#NEXUS [Written by this wonderful piece of code - just because nexus files conventionally contain at least one line of comment :-)] BEGIN DATA; DIMENSIONS NTAX=72 NCHAR=75224; FORMAT DATATYPE = PROTEIN INTERLEAVE = YES GAP = - MISSING = -; MATRIX [Cluster1001.fasta_al_trimmed; alignment length = 152] Allma1 MPPKVDPNEVKIITLRVTGGEVAGGSALAPKIGPLGLSPKKIGDDIAKATTAYKGLRVTVQLTVQNRQAAISVVPSASSLVIGALKEPPRDRKKEKNI--KHSGNLTLDTIIDIARQMRKSLARTLQGTVKEILGTAFSVGCTVDGQSPKDI Ashgo11 MPPKFDPNEVKFLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKDFKGIKVTVQLRIQNRQATASVVPSASSLVITALKEPPRDRKKEKNV--KHTGNLQLDDIIEIARQMRKSFGKNLASVTKEILGTAQSVGARVNYKNPHDI Aspfu1 MATNITPSSIPMSHLRVTGGEVGAQSALAPKIGPLGLSPKKIGEDIAKSTGDWKGLRVTVKLTIQNRQATVSVVPSASSLVIKALKEPPRDRKKEKNI--KHNKSIPFDEIVEIARKMRRSLAKELRGTVLEILGTAFSVGCQVDGRSPKDV Aurde31 MPPKLDPNEIRILHLRVTGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNIPFDEIVDIARTMKKSLARTLANCVKEILGTAQSVGCTVDGKPPHDV Batde5 MPPKADPTEIKYVIIRSTGGEVPGGSVLAPKLGPLGVPPKKAGDDIAKATQAYKGLKVTVRLAVQNRQATVEVLPSASTLLIQALKEPPRDRKKEKNI--KHSGNLTLNQVCEIARKIQKSYAKEFSGNVKEVLGTAFSVGCTVDGQPPQDL Botbo1 MPPKLDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNITLDEIIDIARTMRKSLAKELSGTVKEILGTAQSVGCTIDGQPPHDI Botci1 MPPKLDPNEIKIIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVRLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHSKSITLDEVIEIARTMRKSLAKELKGTVKEILGTAFSVGCQVDGRSPKDV Caeel ---------------------------------------------------------------------------------------------------------------------MRRSMAKKLEGTVKEILGTAQSVGCTIDGQHPHDI Canalb1 MPPKFDPNEVKFLYLRAVGGEVGASSALAPKIGPLGLSPKKVGEDIAKATKEYKGIKVTVQLRIQNRQATASVVPSASSLVITALKEPVRDRKKEKNV--KHSGNIPLDEIFEIARKMQKSFGKNLASVSKEILGTAQSVGCRVDGKNPHDI Cangl MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKDFKGIKVTVQLKIQNRQATASVVPSASSLVITALKEPPRDRKKDKNV--KHSGNVALDEIIEIARQMKKSFGKNLASVTKEILGTAQSVGCRVDFKNPHDI Capow MPPKLDPNEIKIVFLRCTGGEVGAASSLAPKVGPLGLSPKKVGDDIAAATKDWKGLRVTVKLTIQNRKATIDVVPSASTLVIKALNEPPRDKKKEKNI--KHNGNIAFDEVVRIARIMRRSMARTLEGTVKEILGTAQSVGCTIDGKAPHDQ Catan2 MPPKFDPNETKIITLRVTGGEVAGGSALAPKIGPLGLSPKKVGDDIAKATQAYKGLRVTVQLTVQNRQAAISVVPTASSLVIGALKEPPRDRKKEKNI--KHSGNLTLDAIIDVARQMRKSMARTLTGTVKEILGTAFSVGCTVDGMSPKEV Cioin MPPKFDPTAIHYVYLRVTGGEVGATASLAPKIGPLGLSPKKVGDDIAKSTQDWKGLKITVCLKIQNRQATVSVVPSAASLVIKALKEPPRDKKKVKNI--KHNGNITMEDVYGVARIMRRSMSRFFSGTVKEILGTAQSVGCTVDGKPPHDV CocheC53 MPPKFDPSEVKVIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHTKSIPLDEIINIARTMRKSMAKDLKGTTLEILGTAFSTGCKVDGRSPKDV Coere1 MPPKFDPSVIQHITLRTTGGEVAASSALAPKIGPLGLSPKKVGDDIAKATKDWKGLRVTVQLTVQNRQATVSVLPSASSLVIRALKEPVRDKKKDKNI--LHTGNMSIDDVISIAKTMRKSFARELKGTVKEILGTCNSVGCTVDGKTPVAI Conco1 MPPKSDPQEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPTASALVIKALKEPYRDRKKEKNI--KHSGNLNLDQVVEVARVMRKSLARTLQGVVKEVLGTCFSVGCTVEGESPKDI Conpu1 MAPKLDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNIPFDEIVDIARTMKKSLAKELSGTVKEILGTAQSVGCTIDGRPAHDV Copci MAPKFDPNEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKIGEDIAKATSQWKGLRVTVQLTIQNRQATVSVVPSASSLVIKALKEPPRDRKKEKNI--KHSGNIPLEEIIDIARQMRKSLAKELSGTVKEILGTAQSVGCTVNGQPAHDV Croqu1 MPPKIDPNEVKILCLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQATVSVVPSASSLVIKALKEPPRDRKKEKNI--KHTGNITLDEVIEIARKMRKSLAKNLSGTVKEILGTAQSVGCTVDGQPAHDV CryneH991 MPPKFDPSEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHSGNIPLDQIYDIARKMAKSFAKNLSGGVREILGTAHSVGCTVDGKSPHDI Crypa2 MPPKFDPNEVKVIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHNKSVALDEIIEIARTMKKSFSKTLEGTVKEVLGTAFSVGCQVDGKSPKAI Debha1 MPPKFDPSEVKFIYLRAVGGEVGASSALAPKIGPLGLSPKKVGEDIAKATKDFKGIKVTVQLRIQNRQAAASVVPSASSLVITALKEAPRDRKKEKNV--KHSGNIPLEEIYEIARQMRKSFGKTLASVTKEILGTAQSVGCRVEGKNPHDI Dekbr2 MPPKFDPNEIKYLYMRAVGGEVGASASLAPKIGPLGLSPKRIGDQIAKATKDFKGIKVTVQSKIQNRQAEVSVVPSASSLIISALKEPPRDRKKDKNI--QHSGNLTLDQIFEIAKTMSKSFGKTLASVSKEILGTCQSIGCTVDGKPPHDV Dicdi MPPKVDPSEKVEVFLRVCGGEAGAMSTLAPKLGPLGVSPKKVGDDIAKATQPWKGMKVSVKLTIQNRIAVPEVLPSASALVIKALKEPPRDRKKEKNI--KHNGNIPLEEICKIAKTMRKSLAVDFKGSVLEILGTAHSVGCKVNGKSPRDI Dmel MPPKFDPTEVKLVYLRCVGGEVGATSSLAPKIGPLGLSPKKIGDDIAKATSDWKGLKITVCLTIQNRQAAISVVPSAASLIIKALKEPPRDRKKQKNI--KHSGNIGFEDILAIARVMRRSMARELKGTCKEVLGTAQSVGCTVDGKHPHDV Enthi MPPKPNPNEKKELVVKVVAGDAAAGASLGPKVGPLGLNPKKTGDDLAKSTLAWKGLRVTVRITVVNRVATYEVIPSAAALILKALKEPPKDRKKNKGIPTVHSGSISMDDVYEIARTMRRSLAKTFAGTVKEILGTCNSCGCQVDKKSPKQV Falba MPPKFDPTAITIVNLRVTGGEVPGGATLAPKIGPLGLAPKKVGDDIAKGTADWKGLRITVQLTVQNRMAKIAIVPSASSLVIQALKEPVVDRKKVKNI--VHNGNVTMKQIIDIARIMRRSMAKTLTGTVKEILGTAYSVGCTIDGMSAATA Fomme1 MAPKLDPTEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNIPFDEIVEIARTMRKSLAKELKGTVKEILGTAQSVGCTVDSQPPHDI Fusgr1 MPPKFDPNEVKVIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASSLIIKALKEPPRDRKKEKNI--KHNKSVALDEIIEIARTMRKSFAKDLSGTVKEILGTAYSVGCQVDGKPPQSV Galma1 MAPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATSAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNVTLDEIFDIARTMKKSLAKELSGCVKEILGTAQSIGCTVDGQPPHDV Ganpr1 MPPKFDPSEVKIVILRTTGGEVGGASALAPKLGPLGLAPKKVGEDIAKATQSWKGLKVTVKLTVQNRQATIEVVPSASSLVIQALKEPPRDKKKEKNI--KHSGNINLDTIIEIARKMHKSLSKELKGTVKQILGTANSVGCTIDGKAPTEI Gloin1 MAPKIDPNEVKIIYLRATGGEVGASSSLAPKIGPLGLAPKKVGEDIAKATADWKGLRVTVKLTIQNRQAAVSVVPSASSLIIRALKEPPRDRKKEKNI--KHSGNISLDEVIEIARQMHKSFAKSLKGTVKEILGTCNSVGCTVDGQSPKDL Hisca1 ---------------------------------------------------------------------------------------------------------------------MRRSLAKELKGTVLEILGTAFSVGCQVDGRSPKDI Klula1 MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKDFKGIKVTVQLKIQNRQATASVVPSASSLVITALKEPPRDRKKDKNV--KHSGNLQLEDIIEVAKQMRKSFGKNLASVTKEILGTAQSVGCRVNYKNPHDI Lacbi2 MAPKLDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATSAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHSGNVTLDEIFEIARTMKKSLAKELSGCVKEILGTAQSIGCTVNGQPPHDV Lenti61 MAPKFDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATSAWKGLRVTVQLTIQNRQAKVDVVPSASSLVIKALKEPPRDRKKEKNI--KHSGNVTFDEILDIARTMRKSLAKTLANGAKEILGTAQSVGCTVDGQPPHDI Malgl1 MAPKIDPNEVRIIYLRTTGGEVGNPAALAPKLGPLGLAPKKIGEDIAKASGEWKGLRVTVQLTVQNRQAAIAIVPSASSLVIKALKEPLRDRKKTKNI--THSGNIPIDEIIEIARTMRKSFGRTLASTVKEILGTCQSVGCKVDKKHPHDI Mellp23 MPPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQATVAVVPSASSLVIKALKEPPRDRKKEKNI--KHTGNLTLDEVIEIARKMRKSLARNLAGTVKEILGTAQSVGCTVDGQPAHDV Mnele MPPKFDPTATTYVYLKVVGGEVGATSSLAPKIGPLGLSPKKVGDDIAKNTQAWKGLRITVELKIQNRQATVSVVPSAPALIIKALKEPPRDRKKVKNI--AHSGNITIDDIIDIARQMRRSGARYLSGTCKEILGTAQSIGCTVDGQPPHDI Monbr MAPKFDPNAIDYVYLRAVGGEVGATSALAPKIGPLGLSPKKVGDDIAKGTKDWKGLRVTVKLTIQNRKATVSVVPSASSLVIAALKEPVRDRKKEKNV--AHNGNISYNDVYGIAKTMRRSMARAMSGTVKEILGTCQSVGCTVDGKHPHTL Morel2 MPPKLDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATQDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIKALKEAPRDRKKEKNI--KHNGNISLDDVIEIARIMRKSLARELSGTVKEILGTAFSVGCTVDGQNPKDL Mucci2 MPPKFDPSEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKGTKDWKGLRVTVQLTIQNRQAQVSVVPSASSLVIKALKEPLRDRKKEKNI--KHSGNVALEDIIEIARTMRKSLARELSGTVKEILGTAFSVGCTVDGQNPKDL Mydma MGPKFDPTAITIVYLRVIGGEVGATSSLAPKIGPLGLSPKKVGDDIAKATGEWKGLKVTVKLVIQNRNATISVVPSAASLIIKYLKEPPRDRKKVKHV--KHNGDITLDNIFDIARQMRRSLARKFSGTVKEILGTAQSVGCTIDGKSPHDI Neucr2 MPPKFDPNEVKVITLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASALVIRALKEPPRDRKKEKNI--KHNKSVSFDEIVEIARTMRKSFSKELKGTVLEVLGTAFSVGCQVDGKSPKAV Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MPPKFDPNEVKIIHLRVTGGEVGAQSALAPKIGPLGLSPKKIGEDIAKNTGDWKGLRVTVRLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHSKSIPMDEIIEIARIMRRSMAKELRGVVLEILGTAFSVGCQVDGRSPKDV Phybl2 MPPKFDPSEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKGTKEWKGLRVTVQLTIQNRQAQVSVVPSASSLVIKALNEPPRDRKKEKNI--KHSGNVSLEAIIDVARTMRKSLARELKGTVKEILGTANSVGCTVDGQSPKDL Picst3 MPPKFDPSEVKYLYLRAVGGEVGASSALAPKIGPLGLSPKKVGEDIAKATKDFKGIKVTVKLTIQNRQATASVVPSASSLVITALKEPPRDRKKEKNV--KHSGNIPLEEIFDIARQMKKSFGKTLASVSKEILGTAQSVGCRVEGKNPHDI Plicr1 MAPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATTAWKGLRVTVQLTIQNRQAQVAVVPSASSLVIKALKEPPRDRKKEKNI--KHAGNISFDEIIDIARTMKKSLAKELSGTVKEILGTAQSVGCTIDGQPPHDI Polpo MPPKIDPSEKVEVFLRVAGGETGAMSTLAPKMGPLGVSPKKVGDDIAKGTQAWKGLKVQVKLTIQNRVATVEVLPSASALIIKALKEPPRDRKKEKNI--KHHGSVPFEEIIKIAKTMRKSMAIDFQSTVLEILGTANSIGCKVNGKSPRDI Pucgr2 MPPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVAVVPSASSLVIKALKEPPRDRKKEKGI--KHSGNVTLDEIIEIARKMRKSLAKNLAGTVKEILGTAQSVGCTVDGRPAHDV Punst1 MAPKLDPNEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATSAWKGLRVTVQLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHGGNIPLDEIISIARTMRKSLARTLANGCKEILGTAQSVGCTVDGQPPHDI Rhior3 MPPKFDPSEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKGTKDWKGLRVTVQLTIQNRQAQVSVVPSASSLVIKALKEPLRDRKKEKNI--KHSGNISLDDVIEIARTMRKSLARELKGTVKEILGTAFSVGCTVEGQNPKDL Rhoto1 MAPKVDPTEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPPRDRKKEKNI--KHTGNVELDTIIEIARTMRKTLSANLANGVKEILGTAQSVGCTVDGRPPHDV Rozal11 MAPKLDPNEVKILVLRTVGGEVGNTSALAPKLGPLGLSPKKVGEDIAKVSQEWKGLRITAKLTIQNRQATVEIVPNAASLIIKALKEPVRDRKKEKNI--KHSGNLSFEEILNIARQMRKSLARELKGVVREILGTAFSVGCTVEGASPQTI Sacce1 MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNV--KHSGNIQLDEIIEIARQMRKSFGRTLASVTKEILGTAQSVGCRVDFKNPHDI Salro MPPKFDPNEVAYLYMRAVGGEVGATSSLAPKLGPLGLSPKKVGDDIAKATKDWKGLRVTVKLTIQNRKATVAMVPTASALVIKALKEPVRDRKKEKNI--AHDGNITYDDVYEVAKIMRRSMARKMSGTVKEILGTAQSVGCTVDGRHPHDL Schco3 -------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 MPPKFDPNEVKTIFMRAVGGEVAGGSTLAPKIGPLGLSPKKVGEDIAKATKDWKGLRVTVKLTIQNRQAAVSVVPSASALVIKALKEPARDRKKDKNV--AHSGNVSLDEIIEVARTMRKSLAKELSGTVKEILGTAFSVGCTVDGKNPHDV Sorma MPPKFDPNEVKVITLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASALVIRALKEPPQGSQEGE-----------------------EHQAQQV---------------CFA-------- Sphar MPPKPDPSEIKYVVLRAVGGEVAAAATLAPKIGPLGLSPKKIGDDICKATKDWKGLKVTVELAIQNRQATVRIIPAASSLIMRALKEPVRDRKKEKNI--IHDGDIPFDEILEIARAMRRSMARELSGTVKEILGTCQSIGCTIDGEDPHDV Spipu1 MPPKFDPSAVSYVVLRTTGGEVAGGSALAPKIGPLGLSPKKVGEDIAKATKEYKGLRITVRLVIQNRQAAVEVLPSASSLVIQALKEPPRDRKKEKNI--KHTGNLTLDQIIDVARKMRKSYAKELKGTVREILGTAFSVGCTVEGQSPQDI Sporo1 MAPKMDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIRALKEPVRDRKKEKNI--KHTGNIELDQIIEIARTMRKTLSKDLANGVKEILGTAQSVGCTIDGQPPHDI Stehi1 MAPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATTAWKGLRVTVQLTIQNRQAQVSVVPSASSLVIKALKEPPRDRKKEKNI--KHTGNVSLDEIFEIARTMKKSLAKDLAGGVKEILGTAQSVGCTVDGQPPHDV Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr -MASADPIEI---CLRVTGGEVGAAAALAPKVGPLGLSPKRVGEDIAKATGDWKGLRVTVKLTVINRKATVSVVPSAAALIIRALDEPIRDRKKEE-I--KHDGDLSLDAIMDIARQMRRSLARQFSGTVKEILGTAVSVGCTVDGEDPRDI Treme1 MAPKIDPNEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHTGNVSLDEIYNVARKMAKSFAKNLAGGVKEILGTAQSVGCTVDGRPPHDI Trire2 MPPKFDPNEVKIIHLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASSLIIKALKEPPRDRKKEKNI--KHNKSVSLDEMIDIARTMRKSFAKELKGTVREMLGTAQSIGCQVDGKPPQAI Umbra1 MPPKVDPTEIKIITLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKGTADWKGLRVTVQLTIQNRQAQVSVVPSASSLVIRALKEPPRDRKKEKNV--KHSGNISLD------------------------------------------- Ustma22 MAPKIDPNEIKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVQLTVQNRQAAVSVVPSASSLVIKALKEPPRDRKKEKNI--KHGGNIPLDEIVEIARKMRKSFAKSLSGTVKEILGTAQSVGCTVNGQNPHAI Walse1 MAPKIDPNEVKIIYLRAVGGEVGASSALAPKIGPLGLSPKKIGEDIAKASGDWKGLRVTVQLTVQNRQAAVSIVPSASSLVIRALKEPPRDRKKDKNV--KHSGSIPLDEIINIARTMNKSLSKNLSGTVLQILGTCQSVGCTVDRKQPHDL Zygro1 MPPKFDPNEVKFIYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTVQLRVQNRQAQASVVPSASALVITALKEPPRDRKKEKNV--KHSGNIPLDEIIEISRKMRKSFGKNLASVAKEILGTAQSVGCRVDFKNPHDV [Cluster1046.fasta_al_trimmed; alignment length = 178] Allma1 MKDIFKHHDITIPEGVTVSFKSRFVTVTGPRGELKKSFKHVDCELIRVLVWHGDRKHVACIRTVASHIQNMIKGVTKGFLYKMRFVYAHFPINVNIIEVEIRNFLGEKVVRRVPMLEGVKVEHSTGQKDELILSGNDIENVSQSAADIQQSTLVKRKDIRKFLDGIYV--SEKTTIAQ Ashgo11 MKYIQTDQVLDIPEGVTVNIKSRVIKVTGPRGTLEKNLKHIDVTFITITVHNGDRKHVAALRTVKSLISNMITGVTKGYKYKMRYVYAHFPINVNVVEIEIRNYLGDKRVRAVPVREGVSVEFSTNQKDEIVLSGTSIENVSQNAADIQQICRARNKDIRKFLDGIYV--SEKGVIAE Aspfu1 MRYIYSEERLPIPENVKVHIRSRVVTVEGPRGKLVKDLSHIAVTFISIEMHHGARKGVATLRTVRTLINNLIIGVTRGFKYKMRYVYAHFPINVNIEKVEIRNFLGEKIVRRVTAQPGVEVAISSNVKDELQLTGNSLEAVSQSAADIQQICRVRNKDIRKFLDGLYV--SERGNIVE Aurde31 MRDVLQTEELTVPEGVTVEVKSRIITVTGPRGTLKKNVRHTNMDIVTLSVWQGGRKHVACLRTIKSLIQNLIKGVTLGFRYKMRAVYAHFPINCIIQDIEIRNFLGEKTVRHIDMLGGVTISESKAQKDELILEGTDIENVSQSAASIQGACRVRNKDIRKFLDGVYV--SEKGTIST Batde5 MKSISQEQEITIPSEVTLNVAARVFTVKGPRGELTKAFKHVQMDILRVRVWHGGRKHVACIRTICSHVENMIKGVTKGFEYKMRFVYAHFPINANIADIEIRNFLGDKNTRRIPMLDGVTVD-VTSTKDEIVLIGNDIQNVSQSAASIQQSVLVKNKDIRKFLDGIYV--SEKGLFVK Botbo1 MRDVLTTEEITIPEGVTVAIKSRLVTVEGPRGSISKNFRHVNMDIVTLAVWQAGRKHVACLGTIKSLINNMIIGVTKGFLYKMRLVYAHFPINAIIQDVEIRNFLGEKIVRHVAMAEGVKISESKAQKDELILEGIDIQSVSQSAASIQGVCRVRNKDIRKFLDGIYV--SERTTIET Botci1 MKYIHSEETLTIPEGVKVAIKSRQVTVEGPRGKLHKDLSHLAVNFIKIELHHGARKNVATLRTVRTLINNLIIGVTKGFKYKMRYVYAHFPINVNVEKVEIRNFIGEKIVRKVQMREGVAVEPSKNVKDELQLSGNSLEDVSQCAADIQQICRVRNKDIRKFLDGLYV--SEKGNIDE Caeel MKLIESNDTVVFPEGVTFTVKNRIVHVTGPRGTIRKDFRHLHMEMLRVRKWFGVRKELAAIRTVCSHIKNMIKGVTVGFRYKMRSVYAHFPINVTLQDVEIRNFLGEKIVRRVPLPEGVIATISTAQKDEIVVEGNDVQFVSQAAARIQQSTAVKEKDIRKFLDGIYV--SEKTTIVP Canalb1 MKYIQTDQILDIPEGVTVDIKARVVKVTGPRGELTKDLKHIDVTFIKITVHNGDRKHVAALRTVKSLIANLITGVTKGYKYKMRFVYAHFPINVNIIKVEIRNFLGEKRVREVKIHEGVTMEISSTQKDELIVSGNSLEAVSQNAADIQQICRVRNKDIRKFLDGIYV--SERGTIVE Cangl MKYIQTEQSIAVPEGVTVSIKSRVVKVTGPRGTLVKSLKHIDVTFIKVTVHNGDRKHVAALRTVKSLVDNLITGVTKGYKYKLRYVYAHFPINVNTIDIEIRNFLGDKKVRLVPVREGVDVEFSTTQKDELVLSGNSVEDVSQNAADVQQICRVRNKDIRKFLDGIYV--SHKGFIEE Capow MRQILQTSYVDIPENVKVAVKARNVKVTGPRGALEREFKHLNVEMVRVDMWFGNRKELACVRTLTSHINNMIKGVTEGFEYKMKFVYAHFPINVNVIEMEIRNFIGEKVVRTVAMIPGVTVEQQENVKDEIVLRGNSVEDVSLSAAVIQQSVKVHNKDIRKFLDGIYV--SSTGSISV Catan2 MKDILKFHDVTIPEGVTVSFKSRNVVVTGPRGTLKKSFQHVDCELIRVQVYHGNRKHVACIRTVASHIQNLIKGVTKGFLYKLRLVYAHFPINANVVDIEIRNFLGEKVVRRVPMLEGVTIANSQAQKDELIIQGNDIECVSQSAADIQQSVLVKGKDIRKFLDGIYV--SEKTTISE Cioin MKIIHSSQVVTLPDEVKVSVKGRVVTVRGPRGVLKKNFNHLKVELVKVDKWFGNRKDLACVRTICSHINNMATGVTKGYRYKMRSVYAHFPINCNITEIEIRNFLGEKFVRRVDMRAGVKVVSSAKQKDELILDGNDIELVSLSAALIQQSTTVKNKDIRKFLDGIYV--SQKTTIVE CocheC53 MKYIHSEEELPIPEGVKVSIKNRNVVVEGPRGKLSKSLGHLAVSFIKIELHHGIRKSVATLRTVRTLINNLIIGVTKGYKYKMRYVYAHFPINVNLEKVEIRNFIGEKLVRRVVLRPGVEVEASKNVKDQLELSGNSLEDVSQGAADIQQICKVRNKDIRKFLDGLYV--SERGNIVE Coere1 MKHISKEDIVNIPKDVTVVAKSRVIRVTGPRGTLTRDLRHIQMDIIRVVVWQGGRKHIACIRTVCSHINNLIKGVTVGFEYKLRYVYAHFPISVNINKVEIRNFLGERVARKVQINDGVEVTQSTSQKDELVLSGNDVDKVSQSAAAIQQSTRVRNKDIRKFLDGIYV--SEKTTIVK Conco1 MKELTKSETLVIPEGVEITIKARFITVTGPRGTLTKNLRHINCEVISVVVYHGARKHVACIRTAVAHIRNMITGVTKGFLYKMRYVYAHFPINVIVSDVEVRNFLGEKIIRRVSMLEGVTCEISTDAKDEIIIKGNNIEAVSQSAASIQQSTTVKKKDIRKFLDGIYV--SEKTTIVQ Conpu1 MRDVLKTEELDIPEGVTVEIKSRIIKVAGPRGTLTKNVRHIDMDIVTLAVWQGGRKHVACLRTIRSLINNMVIGVTKGFLYKMRAVYAHFPINAIIQELEIRNFLGEKTVRHVKMLDGVTISESKAQKDELILEGNDIENVSQSAASIQGSCRVRNKDIRKFLDGIYV--SDRTTIGQ Copci MLDVQKVEDLEIPEGVDVSVKSRLITVTGPRGTLTKNVRHIDMDIVLLTVWSGSRKHVACLRTIRTMINNMVIGVTKGFQYKMRAVYAHFPINCIIQDVEIRNFLGEKIVRHVDMLEGVVISESKAQKDELILEGNDIDTVSQSAASIQGICRVRNKDIRKFLDGVYV--SHRGTIVE Croqu1 MKDIYKDEELVVPEGVKVTIKARQITVEGPKGKLVKHVKHINMDLIKFIVWHGGRKHVACLRTVKSLVENMITGVTKGFLYKMRTVYAHFPINVIIADVEIRNFLGEKRVRQVPMLEGVSVSESKNTKDEIILEGLDIENVSQSAASIHTSCLVKNKDIRKFLDGIYV--SERTTIEK CryneH991 MKDISSVESLVVPEGVTVAIKARTVTVEGPRGKLTKNVGHIQMDIVVFTVWHGARKHVACLRTVKSLVENMITGVTKGFLYKMRLVYAHFPINALPSDLQIRNFLGEKFVRDCPMLEGVKVSLS-DVKDEIIIQGNDIEKVSQSAASITDKCRVKDKDIRKFLDGVYV--SERTVVVK Crypa2 MKYIHSEETLEIPAGVKMHIKARQITVEGPRGKLVKDLSHIAVSFIAIHIHHGVRKNVAALRTVRTILNNLIIGVTKGFKYKMRYVYAHFPINVNLDKVEIRNFIGEKLVRRVVMQQGVDVEVSKAQKDELVLTGNSLEAVSQSAADIQQICRVRNKDIRKFLDGMYV--SEKGNIVE Debha1 MKYIQTDQILDIPEGVTVQINARSITVTGPRGTLKKDLKHIDVTFIKITVHNGERKHVAALRTVKALIANLITGVTKGYKYKMRYVYAHFPINVNVVEVEIRNFLGEKRVRQIKIFDGVSVEFSANQKDEVVLSGNSLEAVSQNAADIQQVCRVRNKDIRKFLDGIYV--SERGVIDE Dekbr2 MKYVSSVQDIEVPEDVSVIIKSRFVKVTGPKGVLTKDLKHVNVTFIQAHIHNGDRRHVATLRTVKSLITNMITGVTVGFLYKMRFVYAHFPINVSVIEVEIRNFLGDKKLRRVDVPKDVKAEISKAQKDELIVSGISVEEVSQTCANIHQICLVRHKDIRKFLDGIYV--SEKGHIIE Dicdi MKVINSSRKVQIPENVTVDVKGRSVKVTGPRGTLSKSFDHASVDILTVDLWFGNRKQIACIKTITSIIENMITGVTKGYEYKMRFVYAHFPINVAVTDVEIRNFFGEKIVRRIELLDGITCYRNEKAKDEIVLTGNSLELLSQSCATIQLRSAIKYKDVRKFLDGIYV--SERNVLES Dmel MRTINSNQCVKIPKDIKASVKARVVTITGTRGTLKRSFKHLALDMLKVEKWFGTKKELAAVRTVCSHIENMIKGVTFGFQYKMRAVYAHFPINCVTSEIEIRNFLGEKYIRRVEMAPGVTVVNSTAQKDELIVEGNDIESVSGSAALIQQSTTVKNKDIRKFLDGLYV--SEKTTVVK Enthi PRLLKKTEHVVIPEGVTIEINKKNIKVTGPRGTLTREFQHPKVDIVVIDMWYGNRRDSAVVRTIASHIKNMITGVTKGYQYKMRVVYAHFPVTLVIADIQVQNFLGEKRTRHIEMYDGVVVK--KLGKDEICLEGNDVEKVSQSAANIHAANLVRNKDIRQFLDGVYV--SEKCLIEN Falba MRPVQTLQKIVYPEDVSCKFNGRTVTVTGPRGTLTRTFDYVSIELISVCVWFGHRKHVACVNTIVTHIKNMITGVTKGFEYKMRYVYNHFPINV-IVEVEIRNFLGERRVRVIEML-GETVAAPSSMKDELILTGNDIDHVSQSAASIQQACLVKNKDIRKFLDGIYV--SERGTVVK Fomme1 MRDVVQTEELDVPEGVTVDIKSRLITVTGPRGTLKKDVRHVQMDIITLAVWQGGRKHNACLRTIRSLINNLIIGVTKGFQYKMRAVYAHFPINCIIQDLEIRNFLGEKTVRNVKMLAGVTVAESKAQKDELILEGTDIQNVSQSAASIQGICRVRNKDIRKFLDGIYV--SERGTIET Fusgr1 MKYIHSQELLEIPEGVKVAIKSRIVTVEGPRGKLVKDLSHLAVNFISIEIHHGVRKNVATLRTVRTLINNLIIGVTKGFKYKMRYVYAHFPINVNVSQVEIRNFIGEKLVRRIVMHPGVDVEASTTQKDELVLSGNSLENVSQSAADIQQICRVRNKDIRKFLDGLYV--SEKGNVVQ Galma1 MRDVLKTEELEIPSGVEVAVKSRLITVTGPRGTLTKNVRHVDMDIVTLAVWQGGRKHVACLRTIRSLINNMVTGVTKGFRYKMRAVYAHFPINCIIQEVEIRNFLGEKTVRHVNMLSGVDVSESKAQKDELILEGNDIDMVSQSAASIQGICRVRNKDIRKFLDGIYV--SDKGTIVG Ganpr1 MKHIHTEQDVLIPEGVKIDFKARKVTVEGPRGKLSKDFSHVNIEIIKVVVWHGARKHIACIRTICTHIQNLIKGVTKGYEYKMRFVYAHFPINVNIADIEIRNYIGEKIVRRVEMLEGVTVAHSTGQKDEIIVSGNDVEKVSMSAATIQQSTTVRNKDIRKFLDGIYV--SEKGHIAK Gloin1 MKDICKIEEFTIPKNVKVKVKSRIVTVEGERGSLTKNLRHIDLEIIKLIVWHGTRKHVACLRTVKAHIENMITGVTKGFEYKMRYVYAHFPINVHISDVEIRNFLGEKVIRRVKMLEGVDIEISKNLKDELILTGNDLENVSQSAANIQQSTTVKNKDIRKFLDGVYV--SERGRVVK Hisca1 --------------------------MTG-FGAVSRRLDN-----------------------------------------------AQF--------IVDQNFLGEKRVRRVVCQPGVDIIVSPNVKDELQLSGNSLEGVSQSAADIQQICRVRNKDIRKFLDGVYV--SEKGNITE Klula1 MKYIQTDQVLDVPEGVTVQIRSRIIKVTGPRGVLTKNLKHIDVTFIKITVHNGDRKHVAALRTVKSLISNLITGVTKGYKYKLRYVYAHFPINVNVIEIEIRNFLGDKKVREVPVREGVSVDFSTNQKDEIVLSGNSVENVSQNAADIQQICRVRNKDIRKFLDGIYV--SEKGLIEE Lacbi2 MRDVLKTEELEIPSNVEITIKSRLITVTGPRGTLTKNVRHVDMDIVTLAVWQGGRKHVACLRTIRSLINNMITGVTKGFQYKMRAVYAHFPINCIIQEVEIRNFLGEKTVRHVNMLSGVVVAESKAQKDELILEGNDIDMVSQSAASIQGVCRVRNKDIRKFLDGIYV--SDRGTIAT Lenti61 MRDVLKTEELDVPEGVTVEIKSRLITVTGPRGKLTKNVRHIDMDIVTLAVWQGGRKHVACLRTIKSLIVNMITGVTKGYQYKMRAVYAHFPINCIIQDLEIRNFLGEKIVRHVAMLEGVTVSESKAQKDELILEGIDVQNVSQSAASIQGVCRVRNKDIRKFLDGIYV--SEKGTIDQ Malgl1 MLTIYKDLDLEIPENVTVELQSRIVKVKGPRGELVKNFRHMAMDFLKFIVWHAGRKHLACLRTAKAAVVNMFKGVTVGFQYKMRAVYAHFPINLIIAGVEIRNFLGEKRVRKVQMAEGVTIKDDKAQKDQVLVEGNDINAVSQSAAMLHGVTLVRDKDIRKFLDGIYC--TAKTSIEQ Mellp23 MKDIYKDEELIVPEGVKVAIKARQITVEGPRGKLVKHVKHINMDLVKFVVWHGGRKHVACLRTVKSLVENMITGVTKGFLYKMRSVYAHFPINIIIADVEIRNFLGEKRVRQVPMLDGVTVAESKNQKDEITLEGLDLDKVSQSAASIHTSCLVKNKDIRKFLDGIYV--SERTTINT Mnele MRFIHAGDSVKIPDNCTVKIDRRIITVDGPRGQLKKSFKHLQCELIDIKVHFPNRKAVACVRTICSHIKNMFTGVQQGYKYKMKSVYAHFPININIINVEVHNFLGEKFVRRVNLLPGVTCKPTGN-KDEIMVEGNDVENVSRSAALIQQSTTVKNKDIRKFLDGVYV--SEKTFIQE Monbr MKVICSSEFVTIPDGVTVEVNQRHIKVTGKRGTLERVFRHIQTEILKVSCWLANKKALSCVRTVASHIKNMIKGVSYGFAYTMKTVYAHFPINLAFDGINIRNFLGEKVVRTRHMLEGVTVK-STSNKDEIVVEGNDIEKVSLSAALIHQSTLVTKKDIRKFLDGIYV--SDVGTVDP Morel2 MKDIYKEEILAIPEGVKVEVKARQVTVTGPRGTLNKNFRHVEMDILRLVVWHGKRKHVACLRTIRSLINNMIIGVTKGYEYKMRFVYAHFPINVIIADVEIRNFLGQKIVMKVPMLEGVTIFHSKDQKDEITLIGNDLGNVSQSAANIQQATTVKNKDIRKFLDGIYV--SQKG-QIK Mucci2 MKDIYKSDELAIPEGVTVSIKSRQVTVEGPRGSLTKNLRHLNIEIIKFVVHHGVRKHVACIRTVRSLINNMIVGVTKGFEYKLRYVYAHFPINVIINDVEIRNFLGQKVVFHVKMREGVTVAASKNQKDELTLTGNSLENVSQSAADIQQSCLVKNKDIRKFLDGIYV--SERN-VME Mydma MKTVLASETIVIPDGVTLEMNGRSITVKGRRGTLHRNFNHLNLELIRVDVWFALRKQLACLRTICSHINNMIKGVQYGFRYKMRSVYAHFPINLNIMEVEIRNYLGEKYNRIVKMKPGVICMLSGT-KDEIIIDGNDIELVSNSAALINQAVRAKNKDIRKFLDGIYV--SEKSTVDP Neucr2 MRYIHSEETLEVPENVKVSIKSRIVTVEGPRGKLVKDLSHIAVNFIGLEIHHGNRKNVAALRTVRTIINNLIIGVTKGFKYKMRYVYAHFPINVNVEKVEIRNFIGEKIVRRVVMQPGVDVEISKAQKDELVLSGNSLEGVSQSAADIQQICRVRNKDIRKFLDGIYV--SEKGNIVE Orpsp11 MKQICQTRDITIPEGVTIEIKARKVRVKGPRGVLYKDFKHVNFQSLRVIMYHGNRKQVACIRTVCTHIENLMKGVTKGFEYKMRLVAAHFPINVNIADVEIRNFLGEKLIRRVPMLDGVTAAYSATQKDEIVISGNDLENVSQSAANIHQACLVKNKDIRKFLDGIYV--SEKGTVVK Pench1 MRYIHSEERLPILDNVKVHIKSRIVTVEGPRGKLVKDLSHIAVTFISIELHHGARKGVATLRTVRTIINNLMIGVTRGFKYKMRYVYAHFPINVNIEPVEIRNFLGEKYVRRITAQPDVDIAPSANVKDELVLTGNSLEGVSQSAADIQQVCRVRNKDIRKFLDGLYV--SEKGNIIE Phybl2 MKDICKQDELIIPNNVKVIVKSRLVTVEGPRGTLTKNFNHLNIEIIKFTVHHGLRKHVACIRTVRSLINNMITGVTKGFEYKMRYVYAHFPINCIINNVEIRNFLGQKVVFRVQMREGVTVEASKNQKDELTLTGNDLEAVSQSAADIQQSCLVKNKDIRKFLDGIYV--SERN-VLE Picst3 MKYIQTDQILEIPEGVHVNINARSIKVTGPRGELTKDLKHIDVTFIKITVHNGDRKHVAALRTVKSLIANLITGVTKGYKYKLRYVYAHFPINVNIVEVEIRNFLGEKRVRNVKIFEGVTIEQSANQKDELVVSGNSLEAVSQNAADIQQICRVRNKDIRKFLDGIYV--SERGTIVE Plicr1 MRDVLKTEELDIPEGVEVSIKSRLIKVTGPRGTLTKNVRHIDMDIVTLAVWQGARKHVACLRTIKSLIQNMVTGVTKGFSYKMRTVYAHFPINCIIQEVEIRNFLGEKTVRNVSMLNGVTIAESSAQKDELILEGNDIDNVSQSAASIQGICRVRNKDIRKFLDGIYV--SEKGTIVT Polpo MKVIKSSKTVDIPAGVTVAVKGRSVKVTGPRGTLKRDFNHMSVDIVLIDLWFGTRDQIAAISTVASHIENMITGVTKGFEYKMRFVYAHFPINVAITDVEIRNFFGEKIVRRIPLLEGVTCTRTEKVKDEIVLVGNDLEKLSQSCANIQLRSVIKYKDVRKFLDGIYSVHSYRHSLQH Pucgr2 MKDIYKDEELAVPEGVKVTIRARTVTVEGPKGTLCKHIKHINMDLVKFVVWHGGRKHVACLRTVKSLVENMIIGVTKGFLYKMRSVYAHFPINIIISDLEIRNFLGEKRVRHVPMLEGVTVTESKSQKDEITIQGLDIEKVSQSAASIHTSCLVKNKDIRKFLDGVYV--SERTTIDK Punst1 MKDVLKTEEYEIPEGVTVEIKSRLITVTGPRGTLTKNVRHVNMDIVTFAVWQGGRKHVAQLRTMRSLVENMVLGVTKGFRYKMRAVYAHFPINCIIQELEIRNFLGEKTVRNVAMLEGVEVAESKAQKDELILIGNDIQNVSQSAASIQGICRVRNKDIRKFLDGIYV--SDRGTLDE Rhior3 MKDIYKQDELEIPEGVKVNIKSRQITVEGPRGVLTKNLRHLAIEIIRFVVHHGLRKHVACIRTVRSLVNNMIVGVTKGFQYKMRYVYAHFPINVIINDVEIRNFLGQKVVFNVTMREGVKVEASKAQKDELLLTGNSLEAVSQSAADIQQSCLVKNKDIRKFLDGIYV--SERN-VLE Rhoto1 MKQVYKEEELEVPEGVTVTVKSRVITVTGPRGTLQKNAQHVDMSIVKLVVWHGGRKHVACLRTIRSQIENMIQGVRYGFAYKMRLVYAHFPINVIIAGVEIRNFLGEKRVRHVKMLEGVTISESKAQKDEIILEGNDVDAVSQSAASIHGQTLVRNKDIRK-TTAVPV--EDAA---- Rozal11 MK-------------VTVSVKSRVVTVKGPRGELFRDFHHTNVEIIKVTVWFGSRKQLACLRTVCASVKNMIKGVTKGFEYKMRLVYAHFPINTNIIQ---------KITRTIEMAPGVSIKVSADVKDELILTGNDIENVSVSAAKIQQSCEVKNKDIRKFLDGIYV--SERGLLIK Sacce1 MKYIQTEQQIEIPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFIKVAVHNGDRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYV--SHKGFIVE Salro MKTLQATRFITIPEGVTVTIKNRVATVTGKRGTLKRAFKHLQLEVIRVDAWLADRKALACVRTFCTHVMNMMKGVTYGYRYVLKAVYAHFPINMQVIDINIRNFLGEKVTRHVCMHDGVIVKASGN-KDELYVEGNDIEKVSLSAALIHQSCLVTRKDIRKFLDGIYC--SETTTIDP Schco3 MRDVLKTEELEIPEGVDVQIKSRQIKVSGPRGTLTKNVRHVDMDIVTLAVWQGGRKHVACLRTIKSLIQNMVTGVTKGFQYKMRAVYAHFPINCIIQELEIRNFLGEKTVRHVDMLDGVVVAESKAQKDELILEGNDIDNVSQSAASIQGICRVRNKDIRKFLDGIYV--SDKSTIVK Schpo1 GRDIYKDETLTIPKGVTVDIKARNVTVTGPRGTLKQNLRHVDIEMIKFIVWHGSRKHNACIRSVYSIINNMIIGVTQGFRYKMRLVYAHFPININLTEVEIRNFLGERITRVIKCLPGVTVSISSAVKDEIILEGNSLENVSQSAANIKQICNVRNKDIRKFLDGIYV--SERGNIEE Sorma MRYIHSEETLEVPENVKVSIKSRIVTVEGPRGKLVKDLSHIAVNFIGLEIHHGNRKNVAALRTVRTLINNLIIGVTKGFKYKMRYVYAHFPINVNVEKVEIRNFIGEKIVRRVVMQPGVDVEISKSQKDELVLSGNSLEGVSQSAADIQQICRVRNKDIRKFLDGIYV--SEKGNIVE Sphar MKTILGTQVITIPEGVTCNVKSRVATVNGPRGKLVKNFNHLNLDIIRVDVWFAGRKDLACVRTVCSHIENMITGVTKGFKYHMRYVYAHFPINVNIENVEIRNFLGEKVVRKITCGEGVTANFEG--KDEISVQGNDIEMVSQAAAQIQQSTTVKRKDIRKFLDGIYV--SKKVHIEG Spipu1 MRSIIQENDIPIPEGVTVDVKARLVRVKGPRGQLVKDFKHVNMEILKIKVWHGGRKHNACIRTISSHIENMITGVTKGFEYKMRFVYAHFPINVNIISVEIRNFLGEKQIRRIKMLNGVKIDHSTAQKDEIILTGNDIDNVSQSAASIQQSTTVRNKDIRKFLDGIYV--SEKGLLVK Sporo1 MKQIYKEEELEIPAGVTVAIKARVITVTGPRGTLQK-VRSTDYECVKLVVWHGGRKHVACLRTIRSQIENMIKGVRFGFAYKMRLVYAHFPINVIISDVEIRNFLGEKRVRHVKMLEGVTIAESKTQKDEIIISGNDVDLVSQSAADIHGQTLVRNKDIRKFLDGIYV--SEKGQCDE Stehi1 MRDVLKTEELEIPEGVTVEVKSRLIKVAGPRATLTKNVRHVNMDIVTLAVWQGGRKHVACLRTIKSLILNMITGVTKGFLYKMRAVYAHFPINCIIQAVEIRNFLGEKTVRHVDMLSGVTISESKTQKDELILEGADIDMVSQSAASIQGICRVRNKDIRKFLDGIYV--SDKTTVLQ Tapde11 MRSIQNEETLEIPDGVTVDIKSRIVKVTGPRGELTKNLQHISMIMISFRVYHGDRKANACLRTVRSLINNMITGVTKGFRYKMRYVYAHFPINVNFLDVEIRNFLGEKVVRKVPMLEGVSVDHSKNQKDELVLEGNSLENVSQSAASIQQSCAVKNKDIRKFLDGIYV--SSRETIAE Thetr MKIIQSAQFVDIPEGVTVTIKSRNVTVTGPRGTLTRRFNHQMLEMVMVQSWHSNRKKLACIRTTASHVQNMIVGVTQGYRYKMRLVYAHFPINTSIVKIEIRNFLGEKRTRVVPMREGVIIKRGEDVKDELILEGNDVEKVSLTCSDIYGSTLVKNKDIRKFLDGVYK--SESGPIPV Treme1 MKDISSIESLNLPEDVTFTIKARTITVEGPRGKLTKKVSHIAMDIIIFTIWHGSRKHVACLRTIKSLVENMIIGVTKGFLYKMRLVYAHFPINAIPGDLQIRNFLGEKYVRDCKMIEGVKVSMS-DVKDEVIIQGNDIESVSQSAASITDKCRVKDKDIRKFLDGIYI--SERTTVVQ Trire2 MRYIHSQETLEIPEGVKVNIKTRIVTVEGPRGKLSKNLGHLAVNFISIEIHHGNRKNVATLRTVRSIIENLIIGVTKGFKYKMRYVYAHFPINVNLDKVEIRNFIGEKIVRRVTMHEGVDVEISKSQKDELILTGNSLENVSQSAADIQQICRVRNKDIRKFLDGLYV--SEKGNVVE Umbra1 MKDIYKDDELIIPENVDITIKSRIVTVKGPRGELTKNLRHLNMEILKFVVYHGNRKHVACIRTVRSIVNNMVTGVTKGFQYKMRYVYAHFPINVIINDVEIRNFLGQKVTFRVKMLEGCSVESSAAQKDELIITGNDLDAVSQSAASIQQATAVKNKDIRKFLDGIYV--SERN-VLE Ustma22 MLQIFKELDLAVPADVSVSVSSRVFTVKGPRGSLTKSLKHMNLDAIKFVVWHAGRKHAACLRTAQACVANMIKGVTVGFQYKMRAVYAHFPINIIIAGAEIRNFLGEKRVRNIAMLEGVTIQEDKAQKDQVLVEGNDIDLVSQSAALLHGATLVRNKDIRKFLDGIYC--TGKDTVVK Walse1 MRSIYNDELLEVPKGVNVDIKSRVITAEGPRGKLTKVVRHINMDLVKIVVWHGGRKHIACLRTVKSLILNMIKGVTKGFLYRMRAVYAHFPINIIIQDVEIRNFLGEKAVRNVKMSEGVTIEESQTQKDEIILTGNDIQNVSQSAAAIQGICRVRNKDIRKFLDGVYV--SSKEQVVQ Zygro1 MKFIQTEQFVQIPEGVSVYIKARSIKVVGPRGTLFKDLKHIDVSFVKITVHNGDRKHVAALRTVKSLVDNLITGVTKGYRYKMRYVYAHFPINVNVVEVEIRNYLGDKQVRHVPVREGVKIEFSKNQKDELILEGNSIENVSQNAADIQQICRARNKDIRKFLDGIYV--SEKGVIED [Cluster1049.fasta_al_trimmed; alignment length = 226] Allma1 MGRVIRAQRKGGIFKSHSAAQLRPLDYTERHGYIKGLIKEIIHDPGRGAPLARVVFRDPYKYKAMFIATEGMYTGQFVYCGKKASLAIGNVLPLPEGTVVCNVEEKAGDRGALARTSGGYATVIGHNHDTRIKLPSGAKKVVKSSCRATVGIVAGGGRIDKPMLKAGRAYHLNKAKRNRWPKTRGVAMNPVDHPHGGGNHQHIGHASTVARNSPAGKKVGLIAARR Ashgo11 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGVVKQIVHDAGRGAPLAKVVFRDPYKYKETFIANEGVHTGQFIYAGKNASLNVGNILPLPEGTIVSNVEERPGDRGALARTSGNYVIVIGHNPDTRIRLPSGAKKIVSSDARGVIGVIAGGGRVDKPLLKAGRAFHKYKVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR Aspfu1 MGRVIRNQRKGSIFTAHTPAQFRTLDYAERHGYVRGVVKEIIHDPGRGAPLAKVQFRHPYKFKETFIANEGMYTGQFIYAGKNAALTVGNILPLPEGTVVTNVEEKSGDRGALGRTSGNYVTVIGHNPETRIKLPSGAKKVVKSTARGMVGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAAHGQKAGLIAARR Aurde31 MGRVIRAQRRHAIFKSHTPARLRPLDFAERNGYIRGIVKEIIHDAGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKATLAVGNVLPVPEGTIICNIEEKVGDRGALARTSGNYATVIGHSEATRIRLPSGAKKAVSARARATIGIVAGGGRIDKPLLKAGRAFHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVPGQKVGLIAARR Batde5 MGRVIRAQRKGGIFKSHTAAKHRPLDYSERHGYIRGLVKEIVHDPGRGAPLAKVVFRNPYKYGQTFIAAEGLFTGQFLYCGKKAGLTIGNVLPLPEGTIVCNIEESIGDRGAIARVSGNYATVIGQNPDTRLKLPSGAKKVLSNKCRATVGIVAGGGRIDKPLLKAGRAFHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGHASTVSRFAPPGQKVGLIAARR Botbo1 MGRVIRTQRRHAIFKAHTPARLRPLDFAERNGYVRGVVKDIIHDSGRGAPLARIVFRDPYRYKETFIATEGLHTGAFVYCGKKAALTVGNVLPLPEGTIVCNVEEKVGDRGALARTSGNYATIIGHSPDTRIRLPSGAKKTVSSSARATVGIVAGGGRIDKPLLKAGRAFHKYRAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Botci1 MGRVIRNQRKGSIFTANTPAQFRTLDYAERHGYVRGVVKDIIHDPGRGAPLAKVVFRDPYRFKETFIANEGMYTGQFIYAGKNANLTVGNVLPLPEGTVISNVEEKAGDRGALGRTSGNYVTVIGHNPDTRVKLPSGAKKVIKSSARGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAAQGQKAGLIAARR Caeel MGRRIRIQRKGGIFKSHNASKLRPLDYAERHGYIKGLVKDIIHDPGRGAPLAIIAFRDPYKYKTTVVAAEGMHTGQFIHCGAKAQIQIGNIVPVPEGTTICNVENKSGDRGVIARASGNYATVIAHNPDTRIRLPSGAKKVVQSVNRAMIGLVAGGGRTDKPLLKAGRSYHKYKAKRNSWPRVRGVAMNPVEHPHGGGNHQHIGHPSTVRRDASAGKKVGLIAARR Canalb1 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGVVKQIIHDPGRGAPLAKVAFRDPYKYKETFIANEGVYTGQFIYAGKKASLNVGNILPLPEGTIVSNVEEKVGDRGALGRTSGNYVIIIGHNPDTRVKLPSGAKKIISSDARGVIGVVAGGGRIDKPLLKAGRAFHKYKVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR Cangl MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGVVKQIVHDAGRGAPLAKVVFRDPYKYKEIFIANEGVHTGQFIYAGKKASLNVGNVLPLPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDTRVRLPSGAKKIISSDARGVIGVIAGGGRTDKPLLKAGRAFHKYKLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR Capow MGRPILAQRKGGVFTAHTAAQFRTLDFAERHGYIRGLVKEIIHDPGRGAPLARVHFRDPYCFAETFIAPEGLYTGQFINCGRKAALAIGNVLPIPEGTVICNVEEKTGDRGGLARTSGNYATIMTHNPDTRIKLPSGSKKVLSSDCRAMVGLVAGGQRIDKPLLKAGAAYHKFKAKRNNWPNVRGVAMNPVEHPHGGGNHQHIGKPGTVRRDCPPGRKVGLIAARR Catan2 YGRVIRAQRKGSVFRAHVAAKLRPVDFAERNGYIKGIVKEIIHDPGRGAPLARVVFRDPYKYRNLFIATEGMHTGQL------STLAVGNVLPLPEGTIVCNIEEKAGDRGAIARASGNYATVIGHNHDTRIKLPSGAKKAVKSACRATVGIVAGGGRIDKPMLKAGRAYHLNKAKRNRWPKTRGVAMNPVDHPHGGGNHQHIGHASTVSRQSPAGKKVGLIAARR Cioin MGRVIRSQRKGSIFKAHTAAKLRSVDFAERHGYIKGIIKDIVHDPGRGAPLVKVQFQDPYKYRETFVAVEGNFTGQSIYCGKKAQLTIGNVLPVPEGTVVCGLEEKTGDRGKLAKTSGNYATIIAHNPDTRVKLPSGAKKLIPSTNRAIIGVVAGGGRIDKPLLKAGAAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGSPSTVRRDASPGRKVGLIAARR CocheC53 MGRVIRNQRKGSIFTANTPAQFRTLDYAERNGYIRGVVKEIVHDSGRGAPLARVSFRNPYKFKETFIANEGMYTGQFIYAGKNAALTIGNVLPLPEGTVLTNVEDKNGDRGALGRTSGNYVTVIGHNPDTRVKLPSGAKKVLPSSCRGMVGIVAGGGRTDKPLMKASRAKHKFAAKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYATQGQKAGLIAARR Coere1 MGRVIRSQRKGSIFTSRTAAKLRSLDYAEREGYIRGLIKEIIHDPGRGAPLAKVQFRDPYRFKELFIATEGMYTGQFVYCGKKAKLAIGNTIPIPEGSIISNIEEKPGDRGAIARASGNYATVIGQNADTRIRLPSGSKKTLQAACRATVGVVAGGGRIEKPLLKAGRAFFKHRAKRNSWPRTRGVAMNPVDHVHGGGNHQHIGKASTVARSSVPGQKVGLIAARR Conco1 MGRVIRGQRKGGIFKSHTAAKHRTLDYAERQGYIRGVVREIVHDPGRGAPLAKVVFRDPYRYKETFLATEGTYTGQFVYSGKKATLSVGNTLPLPEGTIVCNVEEKPGDRGALARTSGSYATVIGHNEDTRIKLPSGAKKVVLSSARATIGIIAGGGRIDKPLLKAGRAYHKYRVKRNSWPRTRGVAMNPVDHPHGGGNHQHIGHASTTPRDASAGQKVGLIAARR Conpu1 MGRVIRAQRKSTIFRAHTPAKLRTLDYAERNGYIRGIVKEIIHDSGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYAGKKAALTVGNVLPVPEGTIVCNVEEKVGDRGALARTSGNYATIIGHSPETRIRLPSGAKKTVSGSARASIGIVAGGGRIDKPLLKAGRAFYRAKSKRNNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKAGLIAARR Copci MGRVIRAQRRHAIFKSHTPARLRNLDFAERNGYIRGVVKEIIHDAGRGAPLAVVVFRDPYRYKETFIATEGLHTGAFVYCGKKATLNVGNVLPIPEGTIVCNIEEKVGDRGALARTSGNYATVIGHNPETRIRLPSGAKKTVSGHARATIGIVAGGGRIDKPLLKAGRAYHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTMARSSVPGQKVGLIAARR Croqu1 MGRVIRNQRKGGIFRAHQPAAFRPLDFAERNGYIRGLVKDIVHEPGRGAPLARVVFRDPYRYKETFIATEGLSTGSFIYCGKKASLTVGNVLPVPEGTIICNVEEKPGDRGSLARTSGNYATVIGHDADTRIRLPSGTKKTVVSTSRATVGIVAGGGRIDKPMLKAGRAYHKFRVKRNCWPKTRGVAMNPVDHPHGGGNHQHIGHASTISRDAVSGQKAGLIAARR CryneH991 MGRVIRAQRKGGIFKSHTPARLRNLDFAEKNGYIRGVVKDIIHDAGRGAPLATVVFRDPYRYKETFLAAEGLSTGSFVYCGKKATLNVGNVLPIPEGTIVCNVEEKIGDRGALARTSGNYATIIGHS-ETRIRLPSGSKKTISSRCRATVGIIAGGGRIDKPFLKAGRKYHAMRAKRNSWPRTRGVAMNPVDHPHGGGNHQHIGHASTMARDAPAGQKAGLIAARR Crypa2 MGRVIRNQRKSSIFHAITPAKFRSLDYAERHGYVRGVVKQIVHDAGRGAPLAKVVFRDPYRFKETFIANEGMYTGQFIYAGKNAALTVGNVLPLPEGTVVSNVEEKVGDRGTLGRTSGNYITIIGHNPDTRIKLPSGAKKVVHSGSRGMIGIVAGGGRTDKPMLKASRAKHKFAVKRNCWPKTRGVAMNPVDHPHGGGNHQHIGKASTINRYAVSGQKAGLIAARR Debha1 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGIVKQIIHDPGRGAPLAKVSFRDPYKYKETFIANEGVYTGQFIYAGKKASLNVGNVLPLPEGTIVSNVEEKSGDRGALGRTSGNYVIIIGHNQDTRVKLPSGAKKILSSEARGVIGVVAGGGRIDKPLLKAGRAFHKYKVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVPGQKAGLIAARR Dekbr2 --------------------------------------------------------------------------------------------------------------------------IVGHNPDTRVKLPSGAKKVISSDARGVIGIVAGGGRIDKPMLKAGRAFYKYRVKRNSWPKNRGVAMNPVDHPHGGGNHQHIGAPSTIGRRAVAGQKVGLIAARR Dicdi MGRIIRAQRKGSVFGAHTTPRFRALDYAERQGYVKGVVKEIIHDPGRGAPLARVVFKGLTQFKQLFIAPEGMHTGQFVFAGKKATLTIGNILPIPEGTIICNVEEKLGDCGAVARCSGNYATIVSHNPDTRIKLPSGSKKNVSSLARAMIGIVAGGGRIDKPMLKAGRAFHKYRVKKNNWPKVRGVAMNPVEHPHGGGNHQHVGHATTTKRDDPAGKKVGLIAARR Dmel MGRVIRAQRKGSVFKAHVAAKLRSLDFAERSGYIRGVVKDIIHDPGRGAPLAVVHFRDPYRYKELFIAPEGMHTGQFVYCGRKATLQIGNVMPLPEGTIICNLEEKTGDRGRLARTSGNYATVIAHNQDTRVKLPSGAKKVVPSANRAMVGIVAGGGRIDKPILKAGRAYHKYKVKRNSWPKVRGVAMNPVEHPHGGGNHQHIGKASTVKRGTSAGRKVGLIAARR Enthi MGRRTLSQRKGSIFKSRSVAQHRAIDFFERHSTVRGLVKSIEHDPGRGAPLARVVFRNPRQYGELFICAEGLYSGQYIYCGSKASLHIGNVLPIPEGTVVCNVESKPGDRGIIARASGNYATVISHNADTRIRLPSGAKKTLKSNCRAMVGIIAGGGRTEKPILKAGVAYRMYKAKRTTWPRVRGVAMNPVDHPHGGGNHQHVGHPTTLKRSSPPGQKAGKVAARR Falba MGRRIRGQRKGSVFGAVTAAKIRSLDFAERNGYIRGLVKEIIHDPGRGAPLARVAFRNPLEHGSTFVAAEGIHTGQFIYCGKKAQMAVGNVVPIPEGSVVCNIEEKVGDRGSLARTSGNYATILSQNPDTRIRLPSGSKKLIPSDCRATIGIVAGGGRTDKPLLKAGRAYHKFRVKRNCWPHVRGIAMNPVDHPHGGGNHQHVGKATTIRRDAPPGRKVGLIAARR Fomme1 MGRVIRAQRRHAIFKAHTPAKLRNLDYAERNGYIRGIVKEIIHDPGRGAPLARVVFRDPYRYKETFIATEGMHTGAFVYCGKKAALTVGNVLPVPEGTIVCNVEEKVGDRGALARTSGNYATVIGHSGETRIRLPSGAKKTISGSARATVGIVAGGGRIDKPLLKAGRAYHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Fusgr1 MGRVIRNQRKGSIFTANTPAKFRNLDYAERHGYLRGVVREIVHDAGRGAPLAKVVFRHPYRFKETFIANEGMYTGQFIYAGKKAALTVGNVLPLPEGTVVSNVEEKIGDRGTLGRTSGNYITIVGHNPDTRIKLPSGAKKVVHSGSRGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAAQGQKAGLIAARR Galma1 MGRVIRAQRRHTIFKAHIPARLRNLDFAERNGYIRGIVKEIIHDAGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKATLAVGNVLPIPEGTIVCNVEEKVGDRGALARTSGNYATVIGHSPDTRIRLPSGSKKTVSGDARATIGIVAGGGRIDKPLLKAGRAYHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Ganpr1 MGRVIRVQRKGGIFKAHTAAQLRPLDFAERHGYIRGIVREIVHDSGRGAPLAVVHYRDPYKYKQITVATEGMYTGQFVYSGKKATLSVGNTLPLPEGAIVCNIEEKVGDRGALARASGNYATVIGHNHDTRVKLPSGAKKVLLSSCRGQIGIVAGGGRIDKPLLKAGRAYHKYRVKRNKWPRTRGVAMNPVDHPHGGGNHQHVGHATTVSRSAPPGQKVGLIAARR Gloin1 MGRVIRSQRKGGIFKSHTAAKLRPLDYAERHGYIRGIVKEIIHDPGRGAPLAKVQFRDPYRYKQTFIATEGLHTGQFIYCGRKATLTVGNVLPVPEGTIICNVEEKIGDRGAIARASGNYATIIGHNHDTRIKLPSGAKKVINSSARATVGIVAGGGRIDKPLLKAGRAYHKYRVKRNCWPKTRGVAMNPVDHPHGGGNHQHIGHASTVSRESAPGQKVGLIAARR Hisca1 MGRVIRNQRKGSIFTAHTPAQFRTLDYAERHGYTRGVVKEIIHDAGRGAPLAKVSFRHPYKYKETFIANEGMYTGQFIYAGKNATLTVGNILPLPEGTVMTNVEEKVGDRGALGRTSGNYVTVIGHNPETRVKLPSGAKKVVKSRSRGMVGIVAGGGRTDKPLLKASRAKHKFSVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYASAGQKAGLIAARR Klula1 MGRVIRNQRKGSIFTSHTAAKLRNLDYAERHGYIRGVVKQIVHDAGRGAPLAKVVFRDPYKYKETFIANEGLHTGQFIYAGKKASLNVGNVLPLPEGTIISNVEERPGDRGALARASGNYVIVIGHNPETRVRLPSGAKKIISSDARGVIGVVAGGGRIDKPLLKAGRAFHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR Lacbi2 MGRVIRAQRRHAIFKSHTPARLRNLDFAERNGYIRGIVKEIIHDAGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKATLTVGNVLPVPEGTIICNVEEKIGDRGALARTSGNYATVIGHSPDTRIRLPSGAKKTISSGARATIGIVAGGGRIDKPLLKAGRAYHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Lenti61 MGRVIRAQRRHAIFKSHTPAQLRPLDFAERNGYVKGIVKEIIHDAGRGAPLARVVFRDPYRYKETFVATEGLHTGAFVYCGKKAQLAVGNVLPVPEGTIVCNVEEKAGDRGALARTSGNYATVIGHSPDTRIRLPSGAKKTVSGSCRATVGIVAGGGRIDKPLLKAGRAFHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Malgl1 MGRVIRSQRKGGIFTAHTPAKFRPFDFAERNGYIRGLVKEIIHDAGRGAPLARITFRDPYHYKETFIAAEGMHTGQFVYCGKKALLSVGNVLPLPEGTIVCNVEEKVGDRGALARTSGNYATVVGHDADSRIRLPSGVKKTVPSSARATVGIVAGGGRIDKPLLKAGRAYHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHIGHSSTVKRGAVPGQKVGLIAARR Mellp23 MGRVIRNQRKGGIFRAHQPAAFRPLDYAERNGYIRGLVKEIVHEPGRGAPLARVVFRDPYRYKETFIATEGLSTGSFIYCGKKASLAVGNVLPVPEGTIICNVEEKPGDRGSLARTSGNYATVIGHDPETRVRLPSGTKKTVASGSRATIGIIAGGSRVDKPMLKAGRAYHKYRVKRNCWPKTRGVAMNPVDHPHGGGNHQHIGHASTISRNAVSGQKAGLIAARR Mnele MGRVIRGQRKGSIFRAHVAVKLRDIDYAERHGYIKGVVKDIIHDPGRGAPLAKIHFRDPYKYKELICAVEGMYTGQFVYCGKKATLGIGNCLPIPEGTIICNVEAKPGDRGKIARASGNYGTVISHNPDSRIKLPSGSKKVLDSKSRAVVGIIAGGGRIDKPLLKAGRAYHKYKVKRNCWPKVRGVAMNPVEHPHGGGNHQHIGHPSTVRRDTSSGAKVGLIAARR Monbr MGRVIRGQRKGSIFTSHTAARLRPVDYAERHGFIKGMVREIIHDPGRGAPLARVVFRDPYRYRETFVCAEGMHTGQFIYCGKKAELSVGNVKPVPEGTIVCNLEEKPGDRGVIARASGNYVTVIAHNSDSRVRLPSGSKKTIPSTCRAMVGLIAGGGRIDKPLLKAGRAYYKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTCKRDTPAGRKVGLIAARR Morel2 MGRVIRAQRKGGIFKSHTAAKLRSLDFAERTGYIRGIVKEVIHDPGRGAPLAKVQFRDPYRYKETFIATEGTYTGQFIYCGKKAALSVGNVLPLPEGTVVCNVEETVGDRGALARTSGGYATVIGHNTDTRIKLPSGAKKVVFSTARATVGIVAGGGRIDKPLLKAGRAYHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGHASTIARDAVPGQKAGLIAARR Mucci2 MGRVIRAQRKGSIFRSHTAAKLRVFDFAERHGYVRGIVKDIVHDPGRGAPLAKVVFRDPYKYKETFIATEGMYTGQFIYAGKKATLNIGNVMPLPEGTVICNVEEKVGDRGSIARTSGNYATVIGHGDDTRIRLPSGSKKVIPSTSRAVIGVVAGGGRIDKPLLKAGRAFHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTMARDSPAGQKVGLIAARR Mydma MGRVIRGQRKGSVFRAHTAAKLRALDFAERNGYIKGVVRDIVHDSGRGAPLAVVVFRDPYKFKELFIATEGMHTGQFVYCGKKAALTIGNVLPVPEGTIVCNLEEKSGDRGKLARASGDYATVVSHNKETRVKLPSGVKKAIPSFNRASIGIVAGGGRIDKPILKAGRAYHKYKAKRNCWPIVRGVCMNPVEHPHGGGNHQHIGFPSTVARDTPAGRKVGLIAARR Neucr2 MGRVIRNQRKGSIFTANTPAKFRSLDYAERHGYIRGVVKEIIHDPGRGAPLARVVFNSPYKFKETFIANEGMYTGQFIYAGKNAALTVGNVLPLPEGTVVSNVEEKVGDRGAIGRTSGNYVTVVGHNPETRIKLPSGAKKVVSSSARGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAAQGQKAGLIAARR Orpsp11 MGRVIRGQRKGSIFTSHTAAQMRPLDYAERNGYVRGLVKEIIHDAGRGAPLARIVFRDPYKYRTLMVATEGMYTGQFIYAGKKANLTVGNVLPVPEGTIICNIEEKTGDRGSIARTSGTYATIIGHSLETRIKLPSGAKKVIESTCRAQIGIVAGGGRIDKPLLKAGRAFYKFKAKRNSWPKTRGVAMNPVDHPHGGGNHQHIGHASTLGRSAPAGQKVGLIAARR Pench1 MGRVIRNQRKGSIFTANTPAQFRTLDFAEAHGYTRGVVKEIIHDAGRGAPLAKVQFRHPYRYKETFIANEGMYTGQFIYAGKNAALTVGNVLPLPEGTVITNVEEKSGDRGALGRTSGNYVTVIGHNPETRVKLPSGAKKVIKNTARGMVGIVAGGGRTDKPLLKAGRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYATQGQKAGLIAARR Phybl2 MGRVIRAQRKGSIFKAHTAAKLRVFDFAERHGYIRGIIKEIVHDPGRGAPLAKVAFRDPYKYKETFIATEGMYTGQFIYCGKKATLNVGNVLPLPEGTIVCNVEEKVGDRGALARTSGNYVTVIGHGDDTRIRLPSGSKKIVPSTSRAAIGIVAGGGRIDKPLLKAGRAYHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGHASTVARDSSAGQKVGLIAARR Picst3 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGVVKQILHDPGRGAPLAKVVFRDPYKYKETFIANEGVYTGQFIYAGKKASLNVGNILPLPEGTIVSNVEEKVGDRGALGRTSGNYVIIIGHNPDTRVKLPSGAKKIISSDARGVIGVVAGGGRIDKPLLKAGRAFHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVAGQKAGLIAARR Plicr1 MGRVIRAQRRHAIFSAHTPARLRALDYAERNGYIRGIVKEIIHDSGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKAALAVGNVLPVPEGTIVCNIEEKVGDRGALARTSGNYATVIGHSGDTRIRLPSGAKKTIAGGARATIGIVAGGGRIDKPLLKAGRAFHKFKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARNAVPGQKVGLIAARR Polpo MGRIIRAQRKGSVFGAHTAPSFRALDYAERNGYIKGVVSEIIHDPGRGAPLARVVFRDTSSFKQLFIAPEGMYTGQFVFAGKKATLTIGNILPVPEGTIVCNLEERVGDCGAIARCSGNYATIVSHNTDTRIKLPSGAKKNIASTCRAMIGIVSGGGRIDKPILKAGRAFHKYRVKKNNWPKVRGVAMNPVEHPHGGGNHQHIGHASTTKRDDPAGKKVGLIAARR Pucgr2 MGRVIRNQRKGGIFKAHQPAAFRPLDFAERNGYIRGLVKEILHEPGRGAPLARVVFRDPYRYKETFIATEGLSTGSFIYCGKKASLTVGNVLPLPEGTIVCNVEEKPGDRGSLARTSGNYATVIGHDPESRIRLPSGTKKTVISSARATVGIVAGGGRIDKPMLKAGRAYHKFKVKRNCWPKTRGVAMNPVDHPHGGGNHQHIGHASTVRRDCVSGQKCGLLAARR Punst1 MGRVIRAQRRHAIFSAHTPARLRTLDYAERNGYIRGVVKDIIHDSGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKAALAPGNVLPLPEGTVVCNIEEKVGDRGALARTSGNYATVIGHSPETRVRLPSGAKKTVSGSARASIGIVAGGGRIDKPLLKAGRAYYKFKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTISRQAVPGQKVGLIAARR Rhior3 MGRVIRAQRKGSIFKSHTAAKLRVFDFAERHGYVRGIVKEIVHDPGRGAPLAKVVFRDPYKYKETFIATEGMYTGQFIYAGKKASLNIGNVMPLPEGTVICNVEEKVGDRGAIARTSGNYATIIGHGDDTRIRLPSGSKKVIPSTSRAVVGIVAGGGRIDKPLLKAGRAYHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTMARDSPAGQKVGLIAARR Rhoto1 MGRVIRNQRKGGIFRAHTPAKLRALDFAERNGYIRGLVKEIVHDPGRGAPLARVVFRDPYRYKETFIATEGLATGSFVYCGRKATLAVGNVLPLPEGTIVCNVEEKAGDRGALARTSGNYATVIGHDADTRIRLPSGAKKSVASSARATIGIVAGGGRIDKPMLKAGRAFHAAKAKRNNWPRTRGVAMNPVDHPHGGGNHQHIGKASTISRHAVSGQKAGLIAARR Rozal11 MGRVIRSQRKGGIFKSHNAAKLRAVDFAERRGYIRGLVKEIIHDPGRGAPLARVIFRDPYRYKALFIASEGMYTGQFVYCGKKASLTVGNVLPLPEGTVICNVEEKAGDRGALARASGNYATIIGHNPDTRVKLPSGAKKVLESACRAMVGVIAGGGRIDKPMLKAGRAYHKYKAKRNCWPKTRGVAMNPVDHPHGGGNHQHIGHASTVSRYAPAGQKVGLIAARR Sacce1 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYREIFIANEGVHTGQFIYAGKKASLNVGNVLPLPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR Salro MGRVIRVQRKGSVFRAHTAAKLRTLDFSERQGYIKGLVKDIIHDPGRGAPLATVVFRDPYRFKELFICAEGMHTGQFIYCGRKAKLTVGNVLPIPEGTIICNLEQKPGSRGNLARASGNYATIIAHNTDTRVKLPSGTKKTMPSTCRAMIGLVAGGGRIDKPLLKAGNAKYKYSAKRNCWPRVRGVAMNPVEHPHGGGNHQHIGHPSTVARATPPGRKVGLVAARR Schco3 MGRVIRAQRRHAIFKAHTPAQLRPLDYSERNGYVRGVVKEIIHDSGRGAPLARVVFRDPYRYKETFIATEGLHTGAFVYCGKKAQLAVGNVIPVPEGTIICNVEEKVGDRGALARTSGNYATVIGHSPDTRIRLPSGSKKTVSGSARATVGIVAGGGRIDKPLLKAGRAYYKFKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Schpo1 MGRVIRAQRKGGIFQAHTAAQLRTLDFAERHGYIRGVVQKIIHDPGRGAPLAKVAFRNPYHYRETFVATEGMYTGQFVYCGKNAALTVGNVLPVPEGTIISNVEEKAGDRGALGRSSGNYVIIVGHDVDTRVKLPSGAKKVVPSSARGVVGIVAGGGRIDKPLLKAGRAFHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHVGHSTTVPRQSAPGQKVGLIAARR Sorma MGRVIRNQRKGSIFTANTPAKFRSLDYAERHGYIRGVVKEIIHDPGRGAPLARVVFNSPYKFKETFIANEGMYTGQFIYAGKNAALTVGNVLPLPEGTVVSNVEEKVGDRGAIGRTSGNYVTVVGHNPETRIKLPSGAKKVVSSSARGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAAQGQKAGLIAARR Sphar MGRVIRGQRKGSVFKSHTSAGIRHIDYAERHGYVKGIIKEIIHDPGRGAPLAKVHFRDPYRYRELFIAPEGVHTGQFIFCGKKASLAIGNVLPVPEGTIICNVEEKAGDRGSMARASGNYCTVVSHNKDTRLRLPSGSKKIVPSKCRATVGIVAGGGRIDKPMLRAGASYHKYKVKRNSWPRVRGVAMNPVEHPHGGGNHQHIGFPSTVRRDAPAGAKVGLIAARR Spipu1 MGRVIRAQRKGGIFKSHTAAKHRTQDFAERHGYIRGLVKEIIHDPGRGAPLAKVIFRDPYRYKETFIATEGMFTGQFIYCGKKAALTVGNVLPLPEGTVICNLEEKAGDRGAIARCAGNYATVIGHNPDTRVKLPSGAKKVLDSGCRAAVGIIAAGGIVDKPLLKAGRAHFKYRAKRNAWPRTRGVAMNPVDHPHGGGNHQHIGHASTVSRHAPPGQKVGLIAARR Sporo1 ---VIRNQRKGGIFRAHTPAKLRALDFAERNGYIRGLVKEIVHDPGRGAPLARVVFRDPYRYKETFVATEGLSTGAFVFCGKKASLAVGNVLPLPEGTIICNVEEQAGDRGALARTSGNYATVIGHDVDTRIRLPSGAKKSVKNDARATIGIVAGGGRIDKPMLKAGRAFHAAKAKKNNFPKTRGVAMNPVDHPHGGGNHQHIGKASTISRQAVSGQKAGLIAARR Stehi1 MGRVIRAQRRHAIFSAHTPAQFRALDFAERNGYVRGIVKEIIHDAGRGAPLARVVFRDPYRYKETFIATEGLHTGAYVYCGKKAALSVGNVLPVPEGTIICNVEEKVGDRGALARTSGNYATVIGHTPETRIRLPSGAKKTVSGGARATVGIVAGGGRIDKPLLKAGRAFHKYKAKRYNWPRTRGVAMNPVDHPHGGGNHQHIGKASTIARSAVPGQKVGLIAARR Tapde11 MGRVIRAQRKGGIFKSHTAAQHRTLDYAERHGYVRGVIKDIIHDPGRGAPLAKVVFRDPYKYKETFIANEGMYTGQFIYAGKKATLNVGNILPLPEGSIASNVEEKMGDRGALGRTSGNYVIVVGHDLDTRLKLPSGAKKIVPSTARGMIGVVAGGGRIDKPMLKAGRAHHKFKVKRNCWPRTRGVAMNPVDHPHGGGNHQHIGKASTMARSSVPGQKVGLIAARR Thetr MGRVIRQQRKGSVFRSHVAAKFRTLDYAEKNGYLKGIVKEIIHDPGRGAPLARVQFRDPYKYRETFIAAEGMYTGQFVYCGKSAQLSVGNVIPLPEGTIVCNVEAKKGDRGTFARTSGNYATIISHNRDTRIRLPSGSKKVIPSTARAMVGIVAGGGRTDKPLLKAGRAYHKYKVKRNCWPRTRGVAMNPVDHPFGGGNHQHIGKPSTKARDAPPGQKTGLMAARR Treme1 MGRVIRNQRKGGIFKSHTPARLRNIDFAEKNGYIRGVVKEIIHDAGRGAPLATVVFRDPYRYKETFIATEGISTGSFIYCGKKATLNIGNVLPIPEGTIVCNVEEKIGDRGALARTSGNYATVIGHG-ETRIRLPSGSKAVISSRCRATVGIVAGGGRIDKPFLKAGRKYHLMRRKRNSWPKTRGVAMNPVDHPHGGGNHQHIGHASTMARDASAGQKAGLIAARR Trire2 MGRVIRNQRKGSIFTANTPAKFRTLDYAERHGYVRGIVKDIIHDPGRGAPLAKVQFRHPYKYKETFIANEGMYTGQFIYAGKRAALTVGNVLPVPEGTVVSNVEEKIGDRGTLGRNSGGYITIVGHNPDTRIKLPSGAKKVVHSRSRGMIGIVAGGGRTDKPLLKASRAKHKFAVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRYAVQGQKAGLIAARR Umbra1 MGRVIRAQRKGGIFKSHTAAKLRSLDYAERNGYVRGIVKEIIHDPGRGAPLAKVVFRDQYKYRQIFIATEGMYTGQFIYCGKKASLSVGNVLPVPEGTIICNVEERDGDRGALARTSGNYATVIGHGDDTRIKLPSGSKKVVSSGARAAIGIVAGGGRIDKPLLKAGRAFHKYKAKRNSWPRTRGVAMNPVDHPHGGGNHQHIGKASTIPRDASAGQKVGLIAARR Ustma22 MGRVIRAQRKGGIFTAHTPAKLRVYDYAERNGYIRGVVKEIIHDAGRGAPLAKVAFRDPYKYRETFVATEGLSTGQFVYCGKKAALNVANVLPLPEGTIVCNVEEKSGDRGSLARTSGNYATIIGHDPNSRIRLPSGAKKTVPSTSRATIGIVAGGGRIDKPLLKAGRAHHKFKVKRNSWPRTRGVAMNPVDHPHGGGNHQHIGKPSTRSRFAPAGQKVGLIAARR Walse1 PGRVIRSQRKGGIFRSHTPAQLRTYDYAERNGYVRGIVKEIIHDAGRGAPLARVVFRDQYRYKETFIATEGLYTGAFVYCGKKAALAVGNVLPVPEGTVICNIEEKSGDRGALARSSGNYATIIGHSEVTRIRLPSGAKKAVVGSSRATVGIVAGGGRIDKPLLKAGRAYHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHIGHASTIARDAPSGQKAGLIAARR Zygro1 MGRVIRNQRKGSIFTSHTAAKLRTLDYAERHGYIRGIVKQIVHDAGRGAPLAKVVFRDPYRYKEIFIANEGVHTGQFIYAGKKASLNVGNILPLPEGTIVSNVEEKPGDRGSLARASGGYVIIIGHNHDTRVRLPSGAKKIISSGARGVVGVVAGGGRTDKPLLKAGRAYHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARR [Cluster1066.fasta_al_trimmed; alignment length = 79] Allma1 KWSKGKVKDKANNAVTLDKATYDKIYKEVPTYRLITPSVVVDRMRISGSLARVALRELESKGLIKLVTAHASQLIYTRA Ashgo11 KWSKKSHKDKAQHAVILDQDKLDRILKEVPTYRYVSVSVLVDRLKIGGSMARVALRHLETEGIIKPISKHSKQAIYTRA Aspfu1 KWSKGKVKDKAQHAVVLEKQTAERLQKEVQSYRLITVATLVDRLKINGSLARKALADLEEKGQIKKVVGHSKMTIYTRA Aurde31 KWSKGKVKDKAQHAVVLDKATYDRINKEVPTFRFISQSILIERLKIGGSLARVAIRHLEAEGQIKRIVHHSGQLIYTRA Batde5 KWSKGRVKDKFNNAVVFDKPTYEKLYKEVPTFKLVTTSILVDRLRINGSLARAAIRELESKGLIRVVSCHGSQGIYTRA Botbo1 KWSKGKVKDKAQHAVTLDKPTYDRIIREVPGFRFVSQSILIERLKINGSLARIAIRHLEKEGQIKRIVHHHGQLIYTRS Botci1 KWSKGKVKDKAQHAVILDKSTSDRLAKDVQSYRLVTVAVLVDRLKINGSLARRCLKELEEKGQIKIVVKHHAGDIYTRA Caeel KWSKGKVRDKLNNMVLFDQATYDKLYKEVITYKLITPSVVSERLKVRASLAKAGLKELQAKGLVKCVVHHHGQVVYTRA Canalb1 KWNKGKVKDKAQHIVILDQEKYDRILKDVPTYKYVSVSVLVDRLKIGGSLARVALRQLEEDGIITPVLKHSKQAIYTRA Cangl KWSKKSHKDKAQHAVILDQEKFDRILKEVPTYRYVSVSVLVDRLKIGGSMARVALRHLEREGIIKPISKHSKQAIYTRA Capow KWSKGKVRDKLNNAVLFDKDGYQRLLKEVPSYKLITPSVLSERLKIRGSLARAALKELADKGLVKLVESHSAQYIYTRS Catan2 KWSKGKVKDKANNAVTLDKATYDKIYKEVPTWRLITPSVLVDRLRLNGSLARVALKELADKGEIKLVSAHGSQLIYTRS Cioin KWSKGKVRDKLNNLILFDKATYDKLYKEVPNYKLITPAVVSERLKIRGSLARRGLIELLNKGLIKQVIQHSSQVIYTRT CocheC53 KWSKGKVKDKAQHAVVLDKTTNDKLQKDVQSYRLITVATLVDRLKINGSLARKALADLEANGQIKKVVGHSKLSIYTRA Coere1 KWSKGKVQDKANNNVYFSEETLGKLEKEVPTYKLITPSVLVDRMRINGSLARRALRELEARGTIRLVSAHNSQLIYTRA Conco1 KWSKGKVKDKANNSVTFDQATLDKLLKEVPTYKLVTPSVLVDRLRISGSLARQAIKDLETQGLIKLVSAHSSQLIYTRA Conpu1 KWSKGKVKDKAQHAVVLDKPTFDRIFKEAPTWRLISQSILIERLKINGSLARVAIRHLERENLIKRIVHHSGQLVYTRV Copci KWSKGKVKDKAVHSVVLDKATYDRILKEVPTFKFISQSILIERLKINGSLARIAIKHLENEGSIKRIVHHGAQLIYTRS Croqu1 KWSKGKVKDKANNAVVLDKPTFDKIFKEVPTFKMISQSVLIDRMKINGSLARVAIQHLEREGLIKRIVHHRGQLVYSAA CryneH991 KWSKGKVKDKANNAVVVDKAVYDRILKEVPTYKLISQSVLIDRMKINGSLARRAIAFLEKEGLIKRVVHHHAQLIYTRA Crypa2 KWSKGKVKDKAQHAVILDKATSEKLYKDVQSYRLVTVATLVDRLKINGSLARHCLKDLEEKGQIRPIVTHSKMKIYTRA Debha1 KWNKGKVKDKAQHVVLLDQDKYDRIMKDVPTYKYVSVSVLVDRLKIGGSVARVALRQLERDGIITPVVKHSKQAIYTRA Dekbr2 KWNKGKVKDRADHMVILDQDKYDRILKDVPTYKFISVSVLVDRLKIGGSVARVALRQMEKDGLIKCVDKHSKQLIYTRA Dicdi KWSKGRSREKLNNAILFDKETYAKLLKEMPTAKVITTAVVSERMKCNGSLARRAIKELLSKGLIKQIIKGHGNGVYTKA Dmel KWSKGKVRDKLNNQVLFDKATYEKLYKEVPAYKLITPSVVSERLKIRGSLAKRALIELREKGLIKQVVQHHSQVIYTRA Enthi SWSKTKVKEKLNNAVLFDKATLDKCTKEVPSMKVITPAVVADRMKITCSLAKILLKDLEKKELIVPVKVDNHIWIYTRS Falba KWSKGKVKDKADNVVILSPETIDRINKEMTTAKVITPSILVERYKINCSVARSVLKGMHTEGKIRLVVSHNAQTIYTRA Fomme1 KWSKGKVKDKAQHAVIPDKATYDRIFKEVPTFRFISQSILIERLKINGSLARVAIRHLAREGLIKKIVHHHSQLIYTRA Fusgr1 KWSKGKVKDKAQHAVVLDKTTSEKLYKDVQSYRLVTIATLVDRMKINGSLARQCLADLEEKGIIKPVVTHSKMKIYTRA Galma1 KWSKGKVKDKALHAVSLDKVTYDRILKEVPTFKFISQSILIERLKINGSLARVAIRHLEKEKQIKRIVHHSAQLIYSEY Ganpr1 KWSKGKVKDKANNAVTIDKALYDKLVKEVPTYKLITPSVLVDRMRVNGSIARKVIKDLELKGLIKVVSTHNSQLIYTRA Gloin1 KWSKGKVKDKANNAVVLDKATYDKLFKEVPTYKLITPSVLVDRLRVNGSLARVAIRELEEKGLIRKISTHGSQLIYTRA Hisca1 KWSKGKVKDKANHAVVLDKATSEKLYKDVQSYRLITVATLVDRLKINGSLARQALADLEEKGQIKKVVGHSKMNIYTRA Klula1 KWSKKSHKDKAKHAVVLDQDKFDRIMKEAPTYRYVSVSVLVDRFKLGGSLARVALRHLENEGIIKPVSKHSKQAIYTRA Lacbi2 KWSKGKVKDKAQHTVALDKVTYDRIMKEVPTFKFVSQSILIERLKINGSLARVAIRHMEKEGHIKRIVHHSAQLVYTRS Lenti61 KWSKGKVKDKAQHAVVLDKPTYDRILKEVPTFRFISQSILIERLKINGSLARVAIRHLEKEGQIKRIVHHSGQLIYSA- Malgl1 KWSKGKVKDKAQNAVYLDKVLYERVIKEVPTFKMITPSVLIDRLKINGSLARLAIRHFEREGQIKPLIHHHGQLVYTRA Mellp23 KWSKGKVKDKANNAVVVDKPTFDKIFKEVPTYKMISQSVLIDRMKINGSLARVAIQHLEREGLIKRIVHHRGQLVYSKE Mnele KWSKGKSRDKLNNAPLFDKSTYAKLVDEVPKYKLITPSIVSERLKVRGSLARFGLKELHEKGLIKLVDQHGSQVIYTRN Monbr -WSKGKSRDKLNNAPLLNKEQQDRLLKEIPVSRLITPSTVSDRLKIKASLARRAIADLIKKDLIKPVVMHHGQIICTRN Morel2 KWSKGKVKDKANNAVILDKTTYDKLMKEVPTYKLVSPSVLVDRLRINGSLARAAIRELANQGLIVPVSTHGAQWIYTRA Mucci2 KWSAKKVKDKANNLVILDKPTYDRLFKEVPTYKLISQSVLVDRLKLNGSLARIAIRELEAQGLIKAISRHHAQVIYTRA Mydma KWSKGKVRDKLNNMVLFDKATYEKLYKEVPQYKLITPSVVSERLKIRLSLARAALVEMKNNGKIREVSVHHAQKIYTRA Neucr2 KWSKGKVKDKAQHAVILDKSTSDKLYKDVQSYRLVTVATLVDRLKINGSLARRCLKDLEEKGQIKQVVGHSKMKIYTRA Orpsp11 KWSKGKVKDKANNAVTFNQETYDRLFKEVPTYKLITPSQLVDRLKINASLARAALKELEQKGLIRLISSHKSQLIYTRA Pench1 KWSKGKVKDKAQHAVVLDKATNDKLQKDVQSYRLITVATLVDRLKINGSLARQALNDLEANGQIKKVVGHSSLSIYSAL Phybl2 KWSAKKVKDKSNNLVVLDKPTHERLFKEVPTYKLISQSVLVDRLRLNGSLARIAIRELEAQGLIKPLSRHHAQVIYTRA Picst3 KWNKGKVKDKAQHVVILDQDKYDRILKDVPTYKFVSVSVLVDRLKIGGSVARVALRQLEDDGIIAPVLKHSKQAIYTKV Plicr1 KWSKGKVKDKAQHAVTIDKPTFDRVMKEVPTFRFISQSILIERLKVNGSLARVAIRHLEKEGLIKPIVHHSSQLVYTRV Polpo -------------MILFDKETFNKINKELPGAKVITIASVSDKYKCNGSLARRVIRDFAAKGQIKKVIYGHGSGIFTKT Pucgr2 KWSKGKVKDKANNHVVCDKPTYDKIFKEVPTYKMISQSVLIDRMKINGSLARVAIQHLEREGLIKRIVHHRGQLVYTRA Punst1 KWSKGKVKDKAQHAVAVDKPLFDRIMKEVPGFKFISQSILIERLKVNGSLARVAIRHLEKEGHIKRIVHHSAQLIYTRA Rhior3 KWSAKKVKDKANNLVILDKPTYERLFKEVPTYKLISQSVLVDRLKLNGSLARIAIRELEAQGLIKPISRHHAQIIYTRA Rhoto1 KWSKGKVKDKAQNAVICDKPTFDRIMKEVPTFKMISQSVLIERMKINGSLARVAIAHLEKEGLIKPVIRHRAQLVYTRT Rozal11 KWSKGKVKEKSNNAVTFDKNTYDRLFKEVPTYKLITPAVLMDRLKITGSLARRALREFEEKGLIRPVVSHSTLKAYTRA Sacce1 KWSKKSMKDRAQHAVILDQEKYDRILKEVPTYRYVSVSVLVDRLKIGGSLARIALRHLEKEGIIKPISKHSKQAIYTRA Salro KWSKGKTRDKLNNACLFKKDVYQKLLKEVPSYKLITPSIVSDRMKIKASLANKALKELLAKGQIREVVQHNGQRIYTRV Schco3 KWSKGKVKDKAQHAVAVDKPLFDRIIKEVPTFRFISQSILIERLKINGSLARVAIRHLEKEGQIKRIVHHSQQLIYTRA Schpo1 KWSKGKVKDKAQHATVFDKSIIDRINKEVPAFKFISVSVLVDRMKINGSLARIAIRDLAERGVIQKVDQHSKQAIYTRA Sorma KWSKGKVKDKAQHAVILDKSTSDKLYKDVQSYRLVTVATLVDRLKINGSLARRCLKDLEEKGQIKQVVGHSKMKIYTRA Sphar KWSKGKVRDKLNNAVFFDKNTLEKFMKEVKTYKFITPSVVSERLRIGGSLARAALRDLAKEGLIKPVVLHQSQMIYTRA Spipu1 KWSKGKVKDKANNAVVFDKTTYDKLFKEVPTYKLVTPSVLVDRLRINGSLARIAIRELEAKGLIRLVDHHNSQLIYTRA Sporo1 KWSKGKVKDKANNAVVCDKPTYDRIMKEVPTFKMISQSVLIERMKINGSLARVAIQHLEKEGLIKPLIHHRAQLVYTRA Stehi1 KWSKGKVKDKAQHAVMIDKPTYDRIMKEVPTFRFISQSILIERLKIGGSLARVAIRHLEKEGQIKAIVHHHGQLIYTRS Tapde11 KWSKGKVKDKANNAIMLDKNQYDKLFKEVGSYRFVSVSVLVDRLKINGSLARRALVELAEKGIIKEVELSHSQKIYTRA Thetr KWSKTRSRDKIENAVFANEEKYAEIMAEVPKYRLITPSIIAERMRVNGSVARAAIKDMLAEGLIIEVSTHRSQSIYTKA Treme1 KWSKGKVKDKANNAVVLDKPLFDRIVKEVPTYRVITVSTLIDRMKVNGSLARRAIAYLEEEGLIKPVVVHRAQVVYTRA Trire2 KWSKGKVKDKAQHAVLLDKNISDKLYKDVQSYRLVTVAVLVDRMKINGSLARQCIRDLEEKGMIKPVITHSKMKIYTRA Umbra1 -------------MVVLDKQTYERVFKEVPTYKFISQSVLVDRLRLNGSLARVAIRELEDQGVIRRITRHASQVIYTRA Ustma22 KWSKGKVKDKAQNMVVLDRPTYDRILKEVPTFKMISQSTLIDRMKINGSLARVAIRHLEREGQIKRLIHHHGQLVYTRA Walse1 KWSKGKVKDKAQNAVVLDRPTYDRILKEVPTFKLISQSTLIDRLKINGSLARIAIRHLHREGAIRQIVHHNGQLIYTRS Zygro1 KWSKKSHKDKAQHAVIFDQDKYDRMMKDVPSYRYVSVSVLVDRLKVGGSLARVALRHLESEGVIKPVSKHSKQAIYTRA [Cluster1098.fasta_al_trimmed; alignment length = 129] Allma1 VQTFGRK--KTATAVAHCKRGGMIRVNGSPLELVQPEILRYKVYEPILVVGGVDIRVRVNGGGHTSQVYAIRQAIAKAIVAYYAKASKNELRKMLVQYDRSLLVADPRRCEPKKFGGKGARARYQKSYR Ashgo11 VQTFGKK--KSATAVAHVKAGGLIKVNGSPITLVQPEILRFKVYEPLLLVGNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGRGARARFQKSYR Aspfu1 VQCFGKK--KTATAVAHCKQGGLIKVNGQPLSLVQPEILRFKVYEPLLIVGGVDIRVRVSGGGHTSQIYAIRQAIAKSIVAYYQKHSKNQLKQAFVQYDRTLLVADNRRTEPKKFGGRGARARYQKSYR Aurde31 VQTFGKK--KTATAVAHATAGGLIRINGQPIGLVQPEILRYKVYEPVLVVGTIDIRVRVKGGGHTSQVYAIRQAIARALVAYFAKYNALEIKKQLVAYDRTLLIADPRRMEPKKFGGGGARARRQKSYR Batde5 VQCFGRK--KTATAVAHCKRGGLIKINGSPLELVEPEILRAKVYEPIYLLGMVDIRVRVNGGGQVSQIYAIRQAIAKAIVAFYQKSSKKEIKEILIRYDRTLLVADPRRCEPKKFGGAGARARYQKSYR Botbo1 VQTFGKK--KTATAVAHAREGGLVRVNGSPINLVQPEILRYKVYEPILVVGSIDIRVRVKGGGHTSQVYAIRQAIAKAVVAYYAKASALELKKTLVAYDRSLLIADPRRMEPKKFGGQGARARRQKSYR Botci1 VQCFGKK--KTATAVAHCKAGGLVKVNGKPLNLVQPEVLRFKVYEPLLIVGGVDIRVRVTGGGQTSQIYAIRQAISKAIVAYYQKHSKNQLKQALVTYDRTLLVADNRRCEPKKFGGPGARARYQKSYR Caeel VQTFGRK--KTATAVAHCKKGGLIKVNGRPLEFLEPQILRIKLQEPLLLVGDVDIRIRVSGGGHVAQIYAVRQALAKALVAYYHKQSKRELKNIFAAYDKSLLVADPRRRESKKFGGPGARARYQKSYR Canalb1 VQTFGKK--KTATAVAHVKAGGLIKINGSPITLVQPEILRFKVYEPLTLVGGIDIRVKVTGGGHVSQVYAIRQAIAKGLVAYHQKASKNELKKIFASYDKTLLVADSRRMEPKKFGGRGARARFQKSYR Cangl VQTFGKK--KSATAVAHVKAGGLIKVNGSPITLVEPEILRFKVYEPLLLVGNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKQSKNELKKAFTSYDRTLLIADARRPEPKKFGGKGARARFQKSYR Capow VQTFGKK--KTSIAVAHCKRGGLIKVNGVPLDLIQPAALRVKVSEPLLLLGGLDIRVRVAGGGNVAQIYAVRQAIAKAIVAFYQKASKKEIKDLLVAYDRSLLVADPRRAEPKKPGGKGARGKMQKSYR Catan2 VQTFGRK--KTATAVAHCKRGGMLRINGSPIDLVQPEILRYKVYEPILVVGDVDIRVRVSGGGQVSQIYAIRQAIAKAIVAFYAKASKNELRKMLVDYDRTLLVADPRRCEPKKFGGKGARARFQKSYR Cioin VQVYGRK--KTATAVAHCKRGGLIKVNGRPIELVEPETLRYKMEEPILLLGGVDIRIRVKGGGRVAQVYAIRQALAKSLVAYYQKASKKEIKDTLIQYDRTLLVSDPRRKESKKFGGAGARARYQKSYR CocheC53 VQCFGKK--KTATAVAHCKAGGLVKVNGKPLSLIQPEVLRFKVYEPILILGDVDIRVRVSGGGHTSQVYAIRQAIAKSIIAYYQKHSKNQLKQALIQYDRTLLVADNRRCEPKKFGGPGARARYQKSYR Coere1 AQTYGRK--KNATAVAYVKRGGMIRINGHPLQLLEPEILRFKVYEAILIVGGLDIRVRVKGGGQTSQVYAIRQAIAKGIVAFYQKASKKEIKDIIVAYDRSLLVADPRRCEPKKFGGPGARARFQKSYR Conco1 VQVYGRK--KTATAVAHCKRGGQIRVNGSPIDLIQPEVLRFKIYEPILLIGDVDIRIRVSGGGQVSQIYAIRQALAKAIVTFYQKASKKEIKDILVKYDRTLLVADPRRCEPKKFGGQGARARYQKSYR Conpu1 VQTFGKK--KTATAVAHAKEGGLIRINGSPINLVRPEILRYKIYEPILVAGPVDIRVRVKGGGHTSQVYAMRQAIARAIVAYYAKYSAMELKKKLVAYDRSLLIADPRRMEPKKFGGAGARARRQKSYR Copci VQTFGKK--KTATAVAHAKEGGIIRINGSPIHLLQPEILRLKVYEPVLVAGILDIRVRVKGGGHTSQVYAIRQAIAKALVAYYAKFSAIELKKKLVSYDRTLLIADPRRMEPKKFGGPGARARRQKSYR Croqu1 VQTFGKK--KTATAVAFCKDGGLIRVNGVPISLVQPEILRYKVYEPILIAGKLDIRVRVTGGGHTSQVYAIRQALAKAVVAFYAKASALELRKVLIQYDRTLLVADPRRMEPKKFGGKGARSRFQKSYR CryneH991 VQTFGKK--KTATAVAHVTPGGLIRLNGSPISLVEPVVLRYKVYEPVLVVGNMDIRLRVKGGGHVSQLYALRQAIAKGVVAFYAKASAIELKKALVAYDRTLLVADPRRMEPKKFGGRGARARRQKSYR Crypa2 VQCFGKK--RNATAVAQCKAGGLIRVNGRPLQLVEPAILRTKVYEPLLVVGQLDIRVRVSGGGHTSQIYAVRQAISKALIAYNQKHTKNTLKTALTGFDRTLLVADNRRCEPKKFGGPGARARFQKSYR Debha1 VQTFGKK--KTATAVAHVKAGGLIKVNGAPITLVQPEILRFKVYEPLTLVGNIDIRVKVSGGGHVSQVYAIRQAIAKGLVAYHQKASKNELKKVFASYDKTLLVADSRRMEPKKFGGRGARARFQKSYR Dekbr2 VQTFGKK--KNATAVAHVKAGGLIKVNGAPITLVQPEILRHKVYEPILLVGNLDIRIRVTGGGHVSQVYAIRQALAKGLIAYTAKASKNELKKIYTAYDRSLLIADSRRMEPKKFGGRGARARYQKSYR Dicdi VQTHGKK--RTAVAVAYATNGGLIKVNGVPLEFIQPKNLKLKVYEPVLIVGQVDIRVRVRGGGSVAQIYAIRQAIAKSIVAYHQKESKNEIKKKILDYDRSLLVADPRRCEPKKFGGRGARARFQKSYR Dmel VQVFGRK--KTATAVAYCKRGGLLKVNGRPLEQIEPKVLQYKLQEPLLLLGGVDIRVRVSGGGHVAQIYAIRQAISKALVAFYQKASKKEIKDILVQYDRTLLVGDPRRCEPKKFGGPGARARYQKSYR Enthi VQVFGKK--KTAIAVCLCKEGGMIRVNGVPLDLINPPVLRIKVFEPLFIVGKLDLKIRVTGGGQVAQAYAIRQAIAKALIAYNQKTTKNELKAKFLEYDRTLLVADPRRCEAKKFGGPGARAKYQKSYR Falba VQVFGRK--KTATAVAHTKAGGLIKVNGVPLHLIQPEALRLKVQEPILLLGNVDIRVRVSGGGQTSQIYAIRQAIAKSLVAFHQKVSKREIKDILIQFDRTLLVADPRRCEPKKFGGPGARARYQKSYR Fomme1 VQTFGKK--KTATAVAHAREGGLIKINGSPISLLQPEILRFKVYEAVLVLGPIDIRVRVKGGGHVSQIYAIRQAIAKAVIAYYAKASAFELKKKLVAYDRTLLIADPRRMEPKKFGGQGARARRQKSYR Fusgr1 VQCFGKK--KTATAVAHCKAGGLIKVNGRPLQLVQPEILRFKVYEPLLVVGNVDVRVRVSGGGQVSQVYAIRQAIAKSLIAYYQKHSKNLLKQALVQFDRTLLVADNRRCEPKKFGGPGARARFQKSYR Galma1 VQTFGKK--KTATAVAHAREGGLIRVNGSPINLVQPEILRLKVYEPVLVAGPLDIRVRVKGGGHTSQVYAIRQAIAKALVAYYAKYSAMELKKKLVAYDRTLLIADPRRMEPKKFGGHGARARRQKSYR Ganpr1 ------Q--KTATAVAHVKKGGLLHLNGTPLQLLQPEILRFKVYEPVLLLGGVDIRIRVKGGGHTSQVYAIRQALAKGIVAYYQKASKKEIRDILLSHDRTLLVADPRRAEPKKFGGPGARSRYQKSYR Gloin1 VQTYGRK--KTATAVAHCKRGGLIKINGSPIHLVEPEILRFKVYEPILILGGVDIRVRVKGGGHTSQVYAIRQAIAKAIVAFYQKAQKKEIKDTLIHYDRSLLVADPRRCEPKKFGGPGARARY----- Hisca1 VQCFGKK--KTATAVAHCKAGGLIKVNGQPLALTQPEILRFKVYEPLLIVGAVDIRVRVTGGGHTSQIYAIRQAIAKSIVAYYQKHAKNQLKQAFVQFDRTLLVADNRRAEPKKFGGPGARARYQKSYR Klula1 VQTFGKK--KSATAVAHVKAGGLIKVNGSPITLVQPEILRFKVYEPLLLVGNIDIRVKVTGGGHVSQVYAIRQAIAKGLVAYHQKQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGRGARSRFQKSYR Lacbi2 VQTFGKK--KTATAVAHAKEGGLIRINGSPINLVQPEILRLKVYEPVLVAGPLDIRVRVKGGGHTSQVYAIRQAIAKALIAYYAKSSAMELKKKLVAYDRTLLIADPRRMEPKKFGGHGARARRQKSYR Lenti61 VQTFGKK--KTATAVAHAKEGGLIHINGTPLSLLRPEILRFKVYEPILVAGAIDIRLRVKGGGHTSQVYAIRQAIAKAVVAYYAKASALELKKKLVAYDRTLLIADPRRAEPKKFGGHGARARRQKSYR Malgl1 VSCFGKK--KTATAVAHAKEGGQIRLNGQPISLIQPDVLRWKVYEPILMVGPIDIRIRVSGGGHTSQVYAIRQAIAKALVAYYAKASALELRQHFISYDRTLLIADPRRCEPKKFGGHGARARRQKSYR Mellp23 VQTFGKK--KTATAVAFCKDGGLIRINGVPISLVQPEILRYKVYEPILIAGKLDIRVRVSGGGHTSQVYAIRQALAKAVVAFYAKASALELRKVLIQYDRTLLVADPRRMEPKKFGGKGARSRFQKSYR Mnele VQVFGRK--KTATAVAYTKEGGMIKVNGVPIDLLEPSALRYKVLEPILLLGGVDIRIRVRGGGATARVYAIRQAISKSLVAYYQKTSKKEIKDILLNYDKSMLVADPRRCEPKKFGGPGARAKYQKSYR Monbr VQVFGRK--KTATAVAYCKKGGLLKVNGSPLNLYQPATLREKIEEPVNLLGEVDIRVRVKGGGHVAQVYAIRQAIAKALVAYYQKASKKEIKDILLRYDRTLLVADPRRMEPKKFGGPGARARYQKSYR Morel2 VQCYGRK--KTATAVAHCKAGGLIRLNGSPIELVEPDVLKFKVYEPILRVGNVDIRIRVKGGGHTSQIYAIRQALAKAIVAYYQKASKNELKQIFLQYDRTLLVADPRRCEPKKFGGAGARARYQKSYR Mucci2 VQTFGRK--KTATAVAHCKRGGLIRINGSPIELLEPEILKFKVYEVILLLGNTDIRIRVNGGGHTSQVYAIRQALAKAIVAFYQKAAKKEIKEILVQYDRTLLVADPRRCEPKKFGGPGARARFQKSYR Mydma VQVYGRK--KTATAVAFCKAGGMIKVNGRPLDLVEPVSLRMKVQEPVLLLGGVNIQVRVKGGGQVAQLYAVRQAISKAIVAYYQKASKKEIKDVLIQYDRSLLVADPRRCEAKKFGGPGARARYQKSYR Neucr2 VQVFGKK--KNATAVARCVQGGLIKVNGVPLKLYAPEILRAKLYEPILLLGEVDIRLKVSGGGHVSQVYAVRQAIAKAIVAYYAKHSKNTLKTALIQFDRTLLVADPRRCEPKKFGGKGARSRFQKSYR Orpsp11 ---------KTATAVAYCKTGGLLKINGSPIDLVEPDILKFKVYEPILILGNVDIRVTVRGGGHTSQIYGK---------------------------------------------------------- Pench1 VQCFGKK--KTATAVAHCKQGGLVKVNGQPLSLVQPEILRFKVYEPLLIVGGVDIRVRVTGGGHTSQVYAIRQAIAKSIVAYYQKHSKNQLKQALAQYDRTLLVADNRRAEPKKFGGRGARSRYQKSYR Phybl2 VQTFGRK--KTATAVAHCKRGGLVRVNGSPLALLEPEILKFKVYEVILLLGNVDIRIRVNGGGHTSQIYAIRQALAKAIVAFYQKASKKEIKDILVQYDRTLLVADPRRCEPKKFGGPGARARFQKSYR Picst3 VQTFGKK--KTATAVAHVKAGGLIKINGAPITLVQPEILRFKVYEPLTLVGNIDIRVKVTGGGHVSQVYAIRQAIAKGLIAYHQKASKNELKKIFASYDKTLLVADSRRMEPKKFGGRGARARFQKSYR Plicr1 VQTFGKK--KTATAVAHAKEGGLIRLNGSPISLVQPEILRFKVYEPILVAGDVDIRVRVKGGGHTSQVYAIRQAIAKALVAYYSKFSALELKKKLVAYDRTLLIADPRRMEPKKFGGHGARARRQKSYR Polpo VQTHGKK--RNAVAVAYTTEGGSIRVNGVPLSLVQPPTLRLKVYEPLAVAPTLDIRVRVRGGGPVAQVYAIRQALAKAVVAYNQKATKNEIKKAILAYDRSLLVADPRRCEPKKFGGRGARARFQKSYR Pucgr2 VQTFGKK--KTATAVAFCKDGGLIRINGTPIALVQPEILRYKVYEPILIAGKLDIRVRVTGGGHTSQVYAIRQALAKAVVAFYAKASALALRKVLIQYDRTLLVADPRRMEPKKFGGKGARARFQKSYR Punst1 VQTFGKK--KTATAVAHAKEGGLIRINGSPIDLVRPEILRLKVYEPVLVAGVLDIRVRVKGGGHTSQIYAIRQAIAKAVVAYYAKYSAIELKKKLVTYDRTLLIADPRRAEPKKFGGRGARARRQKSYR Rhior3 VQTFGRK--KTATAVAHCKRGGLIRINGSPLELLEPEILKFKVYEVILLLGNVDIRIRTHGGGHVSQVYAIRQALAKAIVAFYQKAAKKEIKEILVQYDRTLLVADPRRCEPKKFAGPGARARYQKSYR Rhoto1 VQTFGKK--KTATAVALAKEGGLIKINGVPLSLYGTPVLRGKVYEPVLILQRMDIRLRVSGGGHTSQLYALRQAIAKAVVAYVAKASALEIRKALVAYDRSLLVADPRRCEPKKFGGRGARARFQKSYR Rozal11 ---------KTATAVAHCKAGGLIKVNGTPIELLEPEILRLKAVEPVMILGKLDIRVRVNGGGHTSQVYAIRQALAKAVVAYYQKASKRQIKETLVSFDRSLLVADPRRCEPKKFGGPGARARYQKSYR Sacce1 VQTFGKK--KSATAVAHVKAGGLIKVNGSPITLVEPEILRFKVYEPLLLVGNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR Salro VQVFGRK--KNATAVALCRQGGLLKVNGSPLSLVQPQLLREKIMEPIQLLGEVDIRVRVKGGGHVAQVYAIRQAISKALVAYYQKSSKKVIKDILVQYDRTLLVADPRRMEPKKFGGPGARARFQKSYR Schco3 VQTFGKK--KTATAVAHAKEGGLIRINGQPINLVQPEILRLKVYEPVLVASIVDIRVRVKGGGHTSQVYAIRQAIAKALVAYYAKYSAMELKKKLVAYDRTLLIADPRRAEPKKFGGHGARARRQKSYR Schpo1 VQCFGKK--GNATAVAHCKVGGLIKVNGAPLSLVQPEILRMKVYEPILVAGGVDIRVRVSGGGHVSQIYAIRQAISKAIVAYYQKHSKAELKKALITYDRTLLVADPRRMEPKKFGGHGARARQQKSYR Sorma VQVFGKK--KNATAVARCVQGGLIKVNGVPLKLYAPEILRAKLYEPILLLGEVDIRLKVSGGGHVSQVYAVRQAIAKAIVAYYAKHSKNTLKTALIQFDRTLLVADPRRCEPKKFGGKGARSRFQKSYR Sphar VQCFGRK--KTATAVAFCKRGGLIRVNGAPIDLVTPQILKLKVMEPLLILGDVDIRVRVKGGGHTSQIYAIRQAIAKSIVAFYQKASKKEIKDLLLRYDRSLLVADPRRCEPKKFGGPGARARFQKSYR Spipu1 VQTYGRK--KTATAVAHCKRGGLIKINGQPLDLVEPAILRTKVYEPIYILGNVDIRVRVEGGGHVSQIYAIRQAIAKAIVAFYQKASKKEIKDLLVHYDRTLLVADPRRCEPKKFGGAGARARYQKSYR Sporo1 VQTFGKK--KTATAVALAREGGLIKVNGIPLSLFGTPVLRAKLYEPIVLLSRMDIRLRVSGGGHTSQIYALRQAIGKAIVAYVSKASALEVRKALVSYDRTLLVADPRRCEPKKFGGNGARSRFQKSY- Stehi1 VQTFGKK--KTATAVAHAREGGLIRINGSPIQLVQPEILRFKVYESILVAGPIDIRVRVKGGGHTSQVYAIRQAISKAVVAYYAKYSAIELKKKLVAYDRTLLIADPRRMEPKKFGGHGARARRQKSYR Tapde11 VQTFGKK--KTSTAVALCKTGGLIKINGSPISLLQPEILRLKVYEPILILGGVDIRCRVTGGGHVSQVYALRQAIAKAIVAYYQKQSKNELKKALIAYDRTLLVADPRRSEPKKPNGKGARSKSQKSYR Thetr VQVFGRK--KNATAVAYCKAGGLIKVNGAPLDLVAPEILRYKLYEPVLLLGGVDIRVRTKGGGSVAQIFAIRQAISRAIVAYYAKASKSEIKNILVNYDRSLIVSDPRRCEPKKFGGPSARARAQKSYR Treme1 VQTFGKK--KTATAVAHVTPGGLVRLNGSPISLVEPALLRYKVYEPILVVGNIDIRLRVKGGGHVSQIYAIRQAIAKGVVAFYAKASALELKKTLIAYDRSLLVADPRRMEPKKFGGRGARARRQKSYR Trire2 VQCFGKK--KTATAVAHCKAGGLIKVNGRPLSLVQPEILRFKVYEPLLVVGNVDIRVRVTGGGHTSQIYAIRQAIAKSLIAYYQKHSKNLLKQALVQFDRTLLVADNRRCEPKKFGGPGARARYQKSYR Umbra1 VQCFGRK--KTATAVAHCKRGGLIRVNGSPVELLEPEIMKFKVYEVVLLLGNIDIRIRVNGGGHVSQIYAIRQALAKAVVAFNQKASKKEIKEILVQFDRTLLVADPRRCEPKKFGGPGARARYQKSYR Ustma22 VSCFGKK--KTATAVAHCKEGGLIRLNGQPISLVQPEILRWKVFEPVLVVGTVDIRLRVSGGGATSQIYAIRQAIAKSLVAYYAKASALELRQLFVAYDRTLLIADTRRSEPKKFGGHGARARRQKSYR Walse1 VQTFGKK--KTATAVATCVSGGLIRVNGSPIQLVQPEILRYKVYEPVLVVGPVDIRVRVSGGGVTSQIYAIRQAISKALVAFYAKASALDLKKTLVSYDRTLLIADPRRCEPKKFGGPGARARVQKSYR Zygro1 VQTFGKK--KSATAVAHVKAGGLIKVNGSPITLVEPEILRFKVYEPLLLVGNVDIRVRISGGGHVSQVYAIRQAIAKGLVAYHQKQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR [Cluster1109.fasta_al_trimmed; alignment length = 126] Allma1 SVKDVDFIPALAAHLKKSGKLQVPAWTELAKTASFKEHGPQDPD-WFYTHAAALARHIYLRRGVGVGALRKVYGGKVRRGCAPNASGSVQRKALQALEKVKILEGKGRQITPTGRRELDRI-ANQV Ashgo11 SVRDVEFINAYASFLQRQGKLEVPGYVDIVKTSAGNEMPPQDSEGWFYKRAASVARHIYLRKQVGVGKLNKLYGGAKNRGVRPHASGSINRRVLQALEKIGVVEG-GRRISENGQRDLDRI-AAQT Aspfu1 TVRDVKFIAAYSAFLKRQGKLPIPGWVDTVKTSCSNELPPQDSD-WYYVRAAAVARHIYMRKTVGVGRLRKVHGSTKNRGSRPNASGSVDRKIIQSLEKIGVLEG-GRRITQAGQRDLDRI-AKTT Aurde31 GVRDVAFIDAYASHLKRSGKLEVPVWADIVKTGAYKELAPYDPD-WFYTRAAAVARHIYLRKHVGIGALAKLHGGRNRRGNRPSASTNVQRKVCQALEKIGVLEG-GRRITQDGQRDLDRI-ATAV Batde5 TVKDVEFIKAYSAYLKRTGKLELPKWVDLVKTGADKELAPYDPD-WYYVRAASVARHIYLRGGVGVGGLRKNYGGTKNRGSKPHGSGSIARAIFHSLEKIKVLQG-GRKISVDGQKDLDRI-AQQI Botbo1 GVRDIEFIVAYSSHLKRSGKLEVPNWADIVKTGAYKELAPYDPD-WFYVRAAAIARHIYLRKHVGIGALAKLHGGRNRRGNRPSCSTSVQRKVCQALEKIGVLEG-GRRISQDGQRDLDRI-ATAV Botci1 TVRDVKFIDAYAAFLKRQGKLPIPGWVDTVKTSASNELPPQSID-WYYVRAAANARHIYLRKTVGVGRLTKVHGSTKNRGSKPSASGSVDRHVLQSLEKIGVLEG-GRRITQSGQRDLDRI-AQTT Caeel SIKDVEATKSIAHFLKKSGKVKVPEWSDLVKLGVNKELAPVDPD-WFYTRAASLARHLYFR-PAGIGAFKKVYGGNKRRGVAPNSAGNCLRKAVQQLEKIKWVEGKGRILSKQGRKDLDRI-ATSL Canalb1 SVRDVDFINAYAQFLQRQGKLEVPGYVDIVKTSAGNDLPPQEAETWFYKRAASIARHIYLRKQVGVGALNKLYGGAKNRGFRPHASGSINRKCVQALQKIGVLEG-GRRISENGQRDLDRI-AAQT Cangl SVRDVDFINAYASFLQRQGKLEVPGYVDIVKTSAGNEMPPQDSEGWFYKRAASVARHIYLRKEVGVGKLNKLYGNAKSRGARPSASGSINRRVLQALEKIGVVEG-GRRISENGQRDLDRI-AAQT Capow TLKDVAFVKAYAAHLKKSGKVELPKYLDLVKTAVGRELPPYDPD-WYYVRLAAIARRLYLHQGLGVGALRVQFGGKKRRGAKPPASGSVIRSAVQQLEKLKVVEG-GRRISQTGQRDIDRI-ASQV Catan2 TVKDVDFIAALSAHLKKGGKIQVPEWMQFAKTATFKELGPSDAD-FYYVHIAAVARHIYLRKGVGVGDLRKRFGGKERRGVRPNASGSLQRKALQTLEKLKYVEG-GRQITATGRRELDRI-ANQV Cioin TVKDVDFVMALAAHLKKSGKMKVPEWVDLIKTGKHKELSPYNPD-WYYVRCASTIRHLYIRGGVGVKSFIKIYGGRKRRGTKPSGSSSVARKVLQSLESIKLVTG-GRRITPSGQRDLDRI-AGQV CocheC53 TVKDITFVKAYAAFLKRQGKLPIPGWVDTVKTSHSNELPPQDID-WFYVRAAAIARHIYMRKTVGVGRLRKVHGSTKNRGSRPSASGSVDRKVMQALEKIGVLEG-GRRITQSGQRDLDRI-AQTT Coere1 TVKDVEFIKAYAAHLKRSGKLEVPAWTEYAKTGSFKELGPYDPD-WFYVRAAAIARHIYIRGGVGIGALAKRMGDSKRRGTRPNASTNVIRKVIQGLEKLGLLEG-GRKITSAGQRDLDRI-SVQV Conco1 TVRDIEFIAAYAAHLKRSAKIEVPAWVDLVKTATHKELAPYDPN-WWYVRAAAVARHIYLRPGVGVGHLRRRAGTSKNRGTRPSATGSVPRKVLQALEKIGILEG-GRRITRAGQRELDQI-AVQV Conpu1 GVRDIAFIVAYSSHLKRSGKLEVPTWVDMVKTGSYKELAPYDPD-WYYVRAAAIARHIYLRKDVGIGALTKLHGGRNRRGNRPSCSSSVQRRICQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Copci GVRDIAFIKAYASHLKRSGKLEVPTWVDLVKTGAYKELAPYDPD-WYYVRAAAVARHIYLRKDVGVGALAKLHGGRNRRGNRPSASTNVQRKICQSLEKIGVLEG-GRRITQDGQRDLDRI-ATAV Croqu1 SVRDIAFIREYAGHLKRSGKIEVPTWVDIVKTGHGNELAPYDPD-WYYVRAAAVARHIYLRKHVGVGALAKLHGGAKNRGNRPSASRSVERKILQGLEKIGVLEG-GRRVSQDGQRDLDRI-ASNI CryneH991 GVRDIAFIKAYSSHLKRSGKLEIPTWVDIVKTGPQKELAPYDPD-WFYVRAAAVARHIYLRKHVGVGALAKLHGTKNRRGTRPSSSTGVQRTVVQSLEKIGVLEG-GRKISQDGMRDLDRI-ATAV Crypa2 SVRDVKFINAYAAFLKRQGKLPIPGWVDTVKTGPAKEMPPQDQD-WFYIRAASVARHVYMRKTVGVGRLRKVHGTAKNRGSRPSASGSVDRKVMQSLEKIGILEG-GRRITQAGQRDLDRIAAQAA Debha1 SVRDVEFINAYAQFLQRQGKLEVPGYVDIVKTSAGNELPPQESETWYYKRAASVARHIYLRKQVGVGKLNKLYGGALNRGFRPHASGSVNRRVLQSLEKIGVLEG-GRKISENGQRDLDRI-AAQT Dekbr2 ------------------------------------------------------------------------------------------------------------------------------ Dicdi TLKDVEFIATYARFLKKTGRVQIPKWNDIAKTATYRELPPTNPD-WIYYRIATLARKVYIRGGDGVATYRRVFGGNRRNGVRPNVNGGNIRYCLKQLQNLKVIEG-GRTITATGRRDLDRI-AKQI Dmel TVKEIVLTKNMAAFLKKSGKIFVPEQAVYMKTGKFKETAPTDDD-WFYTRCASIMRHLYLRSPAGVGAFTKVYSGRKRNGVRPSSSDGCIRKALQALEAANMVEG-GRKLTPQGQRNLDRI-ANKI Enthi NIKDVDFIKAYAEHLKKSGKLEIPEWVDTVKTGMCKELAPLNPD-WIYIRAAAIARKVYLNNGIGVMALRRAYGDQYNKHYNPSGSGKVNRYILQQLEKMGIVA--GRSLTKEGRKDMDKI-AFQV Falba TVRDVEFIHALAAHLKKTGQVAVPEWVDIVKTGNNKELAPTNPD-WFFIRTAAIARQLYLNHTIGVGSLKSIYGGKKRRGARRDASGAVIRASLKALVALNIVEG-TRVVSAKGTSQLDNV-ANAV Fomme1 GVRDVSFIAAYAAHLKRSGKLEVPTWVDIVKTGHYKELAPYDQD-WFYVRAAAVARHIYLRKHVGIGQLAKLHGGRNRRGNRPSASTNVQRKICQSLEKIGVLEG-GRSISQDGQRDLDRI-ATAV Fusgr1 TVRDVKFITAYSAFLKRQGKLPIPGWVDTVKTGPAKELPPQDID-WFYVRAASIARHVYLRKTVGVGRLRKVHGTAKNRGSRPSASGSVDRKVMQSLEKIGVLEG-GRRITQAGQRDLDRI-AQTT Galma1 GVRDVEFITAYASHLKRSGKLEVPAWVDLVKTGSFKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGALTKLHGGRNRRGNRPSSSASVQRKVCQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Ganpr1 TVKDVAFVTAYAAYLKRTGKLDVPKWTDTVKTGTFKELGPYDAD-WYYVRAAAVARHIYLRQGVGVGALRKVYGGRKRRGNRPNSSGSVARKVLQSLEKIKVLEG-GRRITQDGQKDLDRI-ATQL Gloin1 TVKDVDFVKAYAAYLKRAGKLEVPKWVDIVKTGPYKELAPYDPD-WFYIRAAAVARHIYLRNGVGIGALKKLHGGRKRRGTRPSSSGSVARKVLQALEKINVLEG-GRRITQNGQQDLDRI-AQAC Hisca1 TVRDVKFIAAYSAFLKRQGKLPIPGWVDTVKTSKGKELPPQSID-WYYVRAASVARHIYLRKTVGVGRLRKVHGGQKNRGSRPSASGSVDRKVIQSLEKIGVLEG-GRRITQSGQRDLDRI-AKTT Klula1 SVRDVDFINNYASFLQRQGKLEVPGYVDIVKTSAGNELPPQDSEGWFYKRAASVARHIYLRKQVGVGKLNKLYGGAKNRGVRPHASGSINRKVLQSLEKLGVVEG-GRRISDNGLRDLDRI-AAAT Lacbi2 GVRDIAFITAYASHLKRSGKLEVPTWVDLVKTGSFKELAPYDPD-WYYVRAAAVARHIYLRKEVGIGALTKLHGGRNRRGNRPSSSASVQRKICQSLEKIGVLEG-GRKISQDGQRDLDRI-ATAV Lenti61 GVRDIAFISAYASHLKRSGKLEVPTWVDLVKTGSFKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGALTKLHGGAKRRGNRPSSSASVQRKICQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Malgl1 ----------------------MPTWVDIVKTGAYKEQAPYDPD-WWYIRAAALARHVYLHKSVGVGSLCKLHGGPKNRGFRPSASGAVQRKVLQSLEAIGVLEG-GRIISQDGMRDLDRI-AVAV Mellp23 SVRDIAFIREYAGHLKRSGKIEVPTWVDIVKTGHGKELAPYDPD-WYYVRAAAVARHIYLRKHVGVGALAKLHGGAKNRGNRPSASRSVERKILQGLEKIGVLEG-GRRVSQDGQRDLDRI-ASNI Mnele TLKDVMWVKEFAAFLQKSGKLTVPKWTDIVKTATFKELPPKDNN-WFYIRTAALLRRVYLKQGVGCGALRKIYGGRINRGAAPSASASVIRHALKGLEEMKLIAG-GRMITSAGRRDADRI-AFQV Monbr TVKDVQLIAAYAALLKRQGKIPVPSWVDLVKTSTAKELAPYNDD-WFYVRCAALARHLYVRGGVGIGALRRVYGGSKPRGNRPSASGSIIRKALQGLEAIKVVEG-GRKLTRTGQRDLDRI-AQDV Morel2 TVQDIDFNRAYAAYLKRSGKLEIPKWVDLVKTGTNKELAPYDPD-WFYVRAASVARHIYLRRGVGVGALKKLHGGTVNRGSRPSSSGSIARKVLQALEKINVLEG-GRKITVDGQRDLDRI-AASV Mucci2 TVKDVAFIKAYAAYLKRTGKLEVPKWVDLVKTGTFKELAPYDPD-WYFVRAASVARHIYIRKSVGVGALNKVHGGTVNRGSRPSASGSVNRKVLQSLEKIGVLEG-GRKITQDGQRDLDRI-AMTL Mydma TVKDAEFVKAFAGHLKKGNKFKVPEFVEIVKTSKACELGPSDPD-WFYIRAAAVARHIYLRPNLGVGAIRKIYGRAQRNGTRPSGSASIARKVLQSLEAMKLVTG-GRSLTPAGRRDMDRI-AGQV Neucr2 TVRDVKFVNAYAAFLKRQGKLPVPGWVDTVKTGPAKEMPPQDID-WFYVRAASVARHVYLRKTVGVGRLRRVHGTAKNRGSRPSASGSVDRKVLQALEKIGVLEG-GRRITQQGQRDLDRI-AQTV Orpsp11 ----------------------------------------------------SIARHFYLRSNVGIGGLYKSNSSLSRHSIHSSSSGNTIRKIIESFEEMGILEG-GRRLSQKGRKSLDSV-AIQI Pench1 TVRDVKFISAYSAFLKRQGKLPIPGWVDTVKTSASNELPPQDAD-WFYVRAAACARHIYMRKTVGVGRLRKVHGSTKNRGSRPAASGSVDRKALQALEKIGVLEG-GRRITQSGQRDLDRI-AKTT Phybl2 TVKDVEFIKAYSAYLKRTGKLEVPKFVDIVKTGSYKELAPYDPD-WYYVRAASVARHIYIRKSVGVGALNKVHGGRINRGFRPSASGSVNRKVLQSLEKIGVLEG-GRRITQDGQRDLDRI-AMTL Picst3 SVRDVEFINAYAQFLQRQGKLEVPGYVDIVKTSAGNELPPQEAETWFYKRAASVARHIYLRKQVGVGALNKLYGGAINRGFRPHASGSINRKVVQALQKIGVLEG-GRRISENGQRDLDRI-AAQT Plicr1 GVRDIAFITAYASHLKRSGKLEVPTWVDIVKTGSFKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGALTKLHGGRNRRGNRPSSSASVQRKVCQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Polpo TVKDVEFIAHYAKFLKKTGRVHIPRWVDIVKTATHKELPPSNPD-WLYVRIAALARKVYLRGGDGVGCYRKAFGGNRRDGVRPNANGGVIRYCLRQLNVLKVIEG-GRRITATGRRDLDRI-AKPI Pucgr2 SVRDIAFIREYAGHLKRSGKIEVPTWVDIVKTGPCKELAPYDPD-WYYVRAAGVARHIYLRKHVGVGALAKLHGTAKNRGNRPSASRSIERKILQGLEKIGVLEG-GRRVSQDGQRDLDRI-ASNI Punst1 GVRDIAFISAYASHLKRSGKLEVPTWVDIVKTGSYKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGKLTKLHGGRNRRGNRPSASASVQRKVCQSLEKIGVLEG-GRRISQDGMRDLDRI-ATAV Rhior3 TVKDVAFIKAYAAYLKRTGKLEVPKWVDLVKTGTFKELAPYDPD-WYYVRAASVARHIYIRKNVGVGALNKVHGGTVNRGSRPSASGSVNRKVLQSLEKIGVLEG-GRKITQDGQRDLDRI-AMTL Rhoto1 TVRDVAFIAAYSSHLKRSGKLEVPVWVDVVKTGTGKELAPYDQD-WYYVRAAAVARHIYLRKHVGVGALQKLHGGSVNRGNRPSGSGSVERKILQSLEKIGVLEG-GRRISVDGQRDLDRI-ATAV Rozal11 TVKDVSFIAAYAAHLKKSGKFDVPKWVDIVKTGAYKELAPYDPD-WYFIRAASVARHIYLRQGVGVGALKKLHGGRVNRGNRPSGSGSVARKVMQSLEKIKVLEG-GRKITVEGQRDLDRI-ALQV Sacce1 SVRDVDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYASGSINRKVLQALEKIGIVEG-GRRISENGQRDLDRI-AAQT Salro TVKDVKLIHAYAALLKRQGKIKPPAWADYVKTAPFKELAPYDED-WFYVRCASIARHIYIRGGVGIGALRKVYGGSARRGTRPNGSGSVARKCVQALESVRVLAG-GRVITPVGQKDLDRL-ATQI Schco3 GVRDIAFIAAYASHLKRSGKLEVPTWVDIVKTGSFKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGALSKFHGGRNRRGNRPSASASVQRKICQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Schpo1 SVKDVQFINAYAAFLKRSGKMTTPQWIDIVKTGTHKELAPYDPD-WYYVRAAAIARHIYLRKQVGVGRLCKVYGGSVNRGMRPSGSGSVQRKVVQSLEKIGVLEG-GRRISQQGQRDLDRI-AYSL Sorma TVRDVKFVNAYAAFLKRQGKLPVPGWVDTVKTGPAKEMPPQDID-WFYVRAASVARHVYLRKTVGVGRLRRVHGTAKNRGSRPSASGSVDRKVLQALEKIGVLEG-GRRITQQGQRDLDRI-AQTV Sphar TVKDVKFVVALADYLKQSGKIEQPKWVDTVKTATFKELSPYDQD-WFYVRCAAAARHIYVRAPVGVGSMRKIFGGKKRRGCAPNGSASVARAVLKQLDSIGITEG-GRVISSEGRRDLDRI-AGQV Spipu1 TVKDVDFVKAYAAYLKRTGKLEVPKWVDLVKTGTYKELAPYDQD-WYYIRAASVARHVYLRNGVGVGGLKKNYGGRQNRGNRPHSSGSIARKVMQSLEKIKVLEG-GRRISQDGQKDLDRI-AAQI Sporo1 GVRDVAFIAAYSSHLKRSGKLDVPVWVDIVKTGTGKELAPYDPD-WYYIRSAAVARHIYLRKHVGVGALQKLHGSAANRGNRPSASGSIERKILQSLEKIGVLEG-GRRITVDGQRDLDRI-ASAI Stehi1 GVRDIAFITAYASHLKRSGKLEVPTWVDIVKTGAYKELAPYDPD-WYYVRAAAVARHIYLRKDVGIGALIKLHGGRNRRGNRPSASASVQRKVCQSLEKIGVLEG-GRRISQDGQRDLDRI-ATAV Tapde11 ------------------------------------------------------------------------------------------------------------------------------ Thetr NVKDVKFIMALSQFLKENGGMKVPDWAEYVKTAHFKEASPTDND-WYFVRAAAIARQVYLRGATGVGMFKRIYGGKKRNGTAPNGSGAVARSCLNNLETIKFVTN-MRILTSEGRRHMDRI-ATAL Treme1 GVRDIAFIKAYSSHLKRSGKLEIPTWVDIVKTGHHKELAPYDPD-WFYVRAAAIARHIYLRKSVGVGALAKLHGSAYRRGTRPSAATGVQRNVVQALEKIGVLEG-GRKISQDGMRDLDRI-ATAV Trire2 TVRDVKFITAYAAFLKRQGKLPIPGWVDTVKTGPAKELPPQDID-WFYVRAASVARHVYLRKTVGVGRLRKVHGTAKNRGNRPSASGSVDRKAMQALEKIGVLEG-GRRITQSGQRDLDRI-AQTT Umbra1 TVKDVEFVKAYAAYLKRTGKLEVPKWVDIVKTGTYKELAPYDPD-WFYIHAASVARHVYLRPSVGVGALRKVHGGRVNRGSRPSASGSVQRKVLQALEKVNVLEG-GRRISQDGRRDLDRI-AMTL Ustma22 NVRDVTFIDAYAQHLKRSGKIEVPTWVDIVKTGHFKEQAPYNPD-WFYVRAAALARHIYLRKAVGIGHLRKFHGGASNRGFRPSASGSVQRKVVQGLEGIGVLEG-GRRISQDGMRDLDRI-AVAC Walse1 NVRDVSFIEAYSQHLKRSGKIEIPNWVDIVKTGSHKELAPYNPD-WYYVRAAAVARHVYLRKSVGVGALVKFHGGAVNRGHQPYASRGVDRRVVQSLEKIGVLEG-GRKISQDGMRDLDRI-AASI Zygro1 SVRDVEFINAYASFLQRQGKLEVPGYVDVVKTSSGNELPPQDSEGWFYKRAASVARHIYMRKQVGVGKLNKLYGNAKNRGCRPQASGSINRKALQALEKIGVVEG-GRRISENGQRDLDRI-AAQT [Cluster1170.fasta_al_trimmed; alignment length = 148] Allma1 HSFGYRARTRHMFSKNFRQHG-PEHLSTYMKTYHVGDIVDIKANAAIHKG-MPHKFYHGRTGIVYNVTKS-AVGVIVNKRVGNRFMEKRVNLRIEHIKHSKCRDDFLKRVKRAAKESGQLKRQPAQPRAATLV-KIETISAIPYEALV Ashgo11 KSHGYRSRTRYMFQRDFRKSG-TIPLSTYLKVYKVGDIVDIKANGAIHKG-MPHKFYQGKTGVVYNVTKS-SVGVIIYKMVGNRYIEKRLNLRVEHIKHSKCRQEFLERVKAEAKAQGQLKRQPAQPRESRVV-SPQTLSPVPYETFI Aspfu1 HSHGLRSGTRYAFSRGFKEHG-MIRLSTYLKTYRVGDIVDIKVNGAVQKG-MPYKVYNGKTGVVYNVTKS-SVGVIIYKVVGNRYIEKRINVRIEHVKHSRSREDFIKRVKRQAKEQGHLKRQPAMPREGHVV-EAETITPIPYDTHI Aurde31 HSFGYRARTRDMFKRGFKENG-PIKLSTYLISYNVGDIVDIKANAAMQRG-MPHKYYHGRTGIVYNVTPR-AVGVIVHKIVGNRYLEKRVNVRIEHIKHSKCRQEFLDRVKADAKEKGTLKRHPGLPRDAYVV-SPQTMVPLPYETTI Batde5 HSFGLRARTRHLFSRDFRTKG-PVKISTYLKVYKVGDIVDIKANGAIQKG-MPHKYYHGKTGVVYNVTKS-SVGVICHKIVGNRYLEKRVNLRVEHIKHSNCRLDFLQRVKKEARIEGCLKRLPAQPRGARYV-TPITISPVAYEALV Botbo1 HSFGYRARTRHMFKRGFKEHG-PVKLSTFLTPYRVGDIVDIKANAAQQKG-MPHKYYHGRTGVVYNVTPN-AVCVLVKKVVGNRYIEKRVNLRVEHVRHSKCRQDFLDRVGKAAKEKGSLKRVPILPREAYTV-SPQTIVPLPYETTI Botci1 HPAGLRAGTRYAFSRNFKDHG-MIKLSTYLRQYKVGDIVDIKANGAVQKG-MPHKVYHGKTGVVYNVTKS-AVGVIIYKKVKHRYIEKRVNLRIEHVSLSRSREEFVRRVKKQSKTDGHLKRQPAMPREARTI-SPETIVPIAYETTI Caeel NSKGLRRGTRYMFARDFRKHG-VEHLSTYYTQYKRGDLVDIKTNGAFQKG-MPFKAYHGRTGRIFNVTRG-AVGIIVNKRVRGNILPKRINIRIEHIKPSKCRTDFLNRVRKAAKSAGALKRLPVAPRGAHTV-TPELLAPLRFEIVA Canalb1 KSRGYRSGTRYAFQRDFKKHG-AIPLSTYLKVYKVGDIVDIKANGSIQKG-MPHKYYHGKTGIVYNVTKS-SVGVIINKVVGNRYIEKRVNLRVEHVKHSACRQEFLNRVKREAKANGYLKRQAAKPRGSRII-SPQTLAPVAYETFI Cangl KSHGYRSRTRYMFQRDFRKHG-AIALSTYLKVYKVGDIVDIKANGSIQKG-MPHKFYQGKTGVVYNVTKS-SVGVIVNKMVGNRYLEKRLNLRVEHVKHSKCRQEFLDRVRAEAKAQGQLKRQPAQPREARVV-SPQTLAPVAYETFI Capow --MGYREGTRHLFARKFRQHG-AVHLSTYLKTYRVGDIVDIKGNGAVQRG-MPYKYYHGKTGRVFNVTPH-AVGVVVNKQVGNRIINKRVNLRIEHVKHSTCRHDFLDRVRLAAKKDGSLKRQPQQPRVGHVV-RPETLSPLPFDELA Catan2 HSFGYRARTRHLFSKNFREHG-PEHLSTYLKVYRVGDIVDIKANAAIHKG-MPHKFYHGRTGIIYNVTKS-AVGVIINKRVGNRFVEKRVNIRIEHIKHSKCRDDFLKRVKHAAKEAGVLKRQPAQPLPKALI-KIETISPIAYEALV Cioin NTKGYRRGTRYMFSKKFRTRG-VIGLTKYLTVYKKGDIVDIKGDGAVQKG-MPHKVYHGKTGRVFNVTKH-AVGVIVNKQVKGRILAKRINVRVEHVKHSKSRISFLKRVRAVAKQTGNLKRQPKQPRLGHFV-RPELVEPVPWRFIA CocheC53 HAAGLRAGTRYAFSRDFKKKG-MIPLSTYLKQYKVGDIVDVVANGAVQKG-MPYKVYHGKTGIVYNVTKS-AVGVILQKQVGNRYMEKRINVRIEHVRHSRSREDFLKRVQQKAKETGQMKRQPAMPRGERVV-SPENITPVPYETYI Coere1 HSFGYRARTRHMYARDFRKHG-PIHLSTYLKIYKVGDIVDIKGDGAVQKG-LPHKFYHGRTGVVYNVTKS-AVGVIVHKRVGNRYLEKRVNVRIEHVNHSKCRDDFLRRVAKAARESGQLTRQPLQPRKARRV-SPTTITAIPYDTLI Conco1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 HSFGYRARTRDMFKRGFKQHG-PIKLSTYLITYRVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPH-AVGVIVYKVVGNRYLEKRVNLRVEHVRHSKCRQEFLDRVHVKAKETGSLKRQHVLPREARTV-TPQTMRPVPYETTI Copci HSFGYRARTRHMFKRGFRENG-PAKLTTFLTTYRVGDIVDIKANSAQQKG-MPHKFYHGRTGIVYNVTPS-AVGIIVYKVVGNRYVEKRVNIRIEHVKHSKCRQEFLERVHVAAREKGNLKRSPALPREAHVI-SPQTMTPVPYETTI Croqu1 HSFGYRGRTRDMFKRGFKEAG-QIRISTFLRTYRVGDIVDIKANGAQQKG-MPHKYYHGRTGIVYNVAPR-AVGVIVYKVVGNRYLEKRVNLRIEHVKHSKCRDDFLNRVKKEAKEKGVLKRLPAAPREAHII-SPETLVPIPYDTKI CryneH991 HSFGMRARTRHMFRRGFKEHG-APNVSTFLITYRVGDIVDIKANSSQQKG-MPHKFYHGKTGIVYNVTPR-AVGVIIYKVVNGRYMEKRVNIRVEHIRHSKCRQEFLDRVKKEAKEKGLLKRLPAQPREARVV-SPQTLTARPYETFI Crypa2 HAAGLRAGTRYAFSRDFRKKG-MIALSTYLRHYRVGDIVDIKANGAVQKG-MPHKVYHGKTGVVYNVTKS-AVGVIIYKKVKHRYIEKRINLRTEHIQPSRSREGFLRRVKAKAKAEGQVKRQADLPRDARQI-SPETLAPVAYETTI Debha1 KSRGYRSGTRYLFQRDFKKHG-AIPLSTYLKTYRVGDIVDIKANGSIQKG-MPHKYYQGKTGIVYNVTKS-AVGVIIYKVVGNRYLEKRINLRVEHIKHSACRQEFINRVKREAKANGHLKRQPVKPRDARVV-TPQTLAPVPYETFI Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi HSFGLRARTRYLFSRGFRNHG-LLQTTTFLRTFRLGDYVDIKATGNVHKG-MPHKFYHGRTGRVWNVTPR-AVGVIINKRVGPRIIAKKIHVRTEHVKPSNSMAAHLKRIVVEAKKAGDVRRNPAAPKDGFFV-NFVEVKPVKYELLL Dmel NSKGYRRGTRDMFSRPFRKHG-VIPLSTYMRVFKIGDIVDIKGHGAVQKG-LPYKAYHGKTGRIFNVTQH-AVGVIVNKRVRGKILAKRVNVRIEHIHHSKCREDFLRRVLKEAKEKGSLKRQPEQPKKAHFV--PIALAPIPYEFIA Enthi LSNGRNRRTRKLFKRPFRGHG-LSNTSTILHTYKVGDYVTILCNSSIQHG-LPYKAFHGKTGRVWNVNPH-AIGVMVNKKVNNRIVVKRLHISPEHIKPSGCQKDFLERKKKEGKPLLPAKRLPKQPRPAELI-KFTTVAPLKFEELY Falba GTKGYRSGTRHLFAKKFRKHG-VPSLSTHLKVYKVGDIVDVAADASIHRG-MPHKFYHGKTGVVFNVTKR-ALGLIVNKRHGNRIMPKRINVRVEHVKHSKCRDDFLNRVKAEARAKGQLKRLPAGPTPAHTV-ELVTFGAVPYELLI Fomme1 HSYGYRARTRHMFTRGFKEHG-PIKLSTFLVNYRVGDIVDIKANAAQQKG-MPHKFYHGRTGIVYNVTPH-AVGVIVNKVVGNRYIEKRVNIRVEHVRHSKCRQEFLERVRAEAKAKGFLRRIQPAPRESRIV-SPQTIVPVPYETTI Fusgr1 HSYGKRAGTRYAFSRDFRKKG-MIALNTYLRQYRVGDIVDIKANGAVQKG-MPFKVYHGKTGVIYNVTKS-AVGVIIYKQVKHRYIEKRINVRIEHISQSRSREDFLKRVKREAKATGQVKRQPLGPRGAHTL-SPMTVTPLAYETTI Galma1 HSFGYRARTRHMFKRGFKEHG-PVKLSTFLINYHVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPA-AVGVIVYKVVGNRYLEKRVNLRVEHVRHSKCRQEFLDRVHAVAKEKGNLRRIPALPREARTV-SPQTIVPVRYETTI Ganpr1 HSFGLRARTRYLFSRDFRTKG-PIKLSTYLKTYKVGDVVDIKANGAIHKG-MPHKYYQGRTGIIYNVTKS-AVGVIVNKRVGNRIIAKRINLRVEHIKHSHSRDDFLRRVAGDARAKGNLKRQPVQPREAVFVKVPETVNPVPYEALV Gloin1 HSYGIRARTRYMFSRKFRETG-SIRLSTYLKTYKVGDIVDIKANGAVQKG-MPHKFYHGRTGIIYNVTKS-AVGVIINKVVGNRYIEKRVNVRIEHIKHSKCRDDFLRRVKKEARAKGNLKRQPEGPRKSHFV-SPTTITPIPYETLV Hisca1 HSHGLRSGTRYAFSRDYKKHG-VIPLSTYMRVYRVGDIVDIKVNGAVQQGSYAIKVYHGKTGVCLQRDKSLAFGVIIYKRVGNRYI-------------GEARQRPPSSTDGRPKEEGHLKRQPIGPREARTV-SPETITPIAYETTI Klula1 KSHGYRSRTRYMFQRDFRKHG-AIALSTYMKVYKVGDIVDIKANGSIHKG-MPHKFYQGKTGVVYNVTKS-SVGIIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKAEAKAQGQLKRQPAQPKESRVV-SPQTLAPVPYETFI Lacbi2 HSFGYRARTRHMFKRGFKEHG-PVKLSTFLINYRVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPS-AVGVIVYKVVGNRYIEKRVNLRVEHVRHSKCRQEFLDRVHVAAKEKGNLRRIPALPREARTV-SPQTMVPVPYETTI Lenti61 HSFGYRARTRDMFKRGFKEHG-PIKLSTYLTNYRIGDIVDIKANAAQQKG-MPHKYYHGRTGIIYNVTPS-AVGIIIHKVVGNRYIEKRVNIRVEHIRHSKCRQEFLDRVHVEAKAKGNLKRQPVVPRGARTI-SPQTMTPVPYETTI Malgl1 -----------MFAKQFRKHG-QVQLSRYLRPFHSGDIVDIVADSGEQKG-MPHKYYQGRTGVVYSVFPR-AVGVIVHKTVGNRKIEKRVSVRVEHVRHSKCRDNFVNRVKHAAKEKGFLKRQPAQPRAEHTI-TPVTLAPQPYDTYI Mellp23 HSFGYRGRTRDMFKRGFKEAG-QIRISTYLRTYRVGDIVDIKANGAQQKG-MPHKYYHGRTGVIYNVAPR-AVGVIVYKVVGNRYLEKRVNLRVEHVKHSKCRDDFLNRVKSEAKARGVVKRQPAAPREARTV-SPETLVPIPYDTKI Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------- Monbr NTKGLRRGTRYMFSRDFRKRG-PLNLETYLTVYKVGDIVDIKGNGAQQLG-MPYKAYHGKTGRVYNVTKR-ALGVVVNKRIKNRYVAKKINVRIEHVKHSNSRKEFLRRAKAEASARGDVKRQPAGPKPAEFV-NPVRLRPVPFEFMA Morel2 -----------MFARNFREHGMPIKLTTYLKTYKVGDIVDIKANGAIHKG-MPHKFYHGRTGIIYNVTKS-AVGIIINKKVGNRFLEKRVNIRIEHIKHSKCRDDFLRRVKLQAKTDGNLKRQPAMPREARFV-SPTTLNPIPYDTLV Mucci2 HSFGLRARTRHMFSRKFREHG-SIPLSTYLKTYKVGDIVDIKANAAVQKG-MPHKFYHGRTGVIYNVTKS-SVGVLVHKNVGNRYLEKRVNVRVEHIKHSKCRQEFLDRVKKEAKEAGNLKRIPAQPREARHI-SPQTLAPIPYETLI Mydma NPKGKRRGTRYLFSKKFRKHG-VEHLSTYLKTYKVGDIVDVKGNGAIQKG-MPYKFYHGKTGRVFNVTKS-AVGVVVNKQLGNRIIPKKINVRIEHVKHSKCRDDFLRRVKRAAKATGDCRRQPVLPREAHFV-SPILVEPIPYEFII Neucr2 HAAGLRAGTRYAFSRNFREKG-MIRLSTYLKQYKVGDIVDIKVNGAVQKG-MAHKVYHGKTGVIYNVTKS-AVGIIIYKKVKHRYIEKRINVRIEHIQPSRSRDDFLRRVKKQAKAEGQLKRQALLPREARTI-SPETVAPVAYETTI Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 HSYGLRAGTRYAFSRGFKEHG-MIRLSTYMKTYRVGDIVDLKVNGAVQKG-MPHKVYHGKTGVVYNVTKS-AVGVILYKKVDNRYLEKRISVRIEHVQHSRSREDFIKRVKREAKEKGHLKRQAVGPREAHFV-KPETVVPIAYDTHI Phybl2 HSFGLRARTRHMFSRKFRDHG-AIPLSTYLTIYKTGDIVDIKANAAVQKG-MPHKFYHGRTGVVYNVTKS-AVGVIINKRVGNRYIEKRVNIRVEHIKHSKCRQEFLDRVKQAAKDAGSMKRAPVQPRTARYV-SPQTITAIPYETLL Picst3 KSRGYRSGTRYAFQRDFKKHG-TIALSTYLKVYKVGDIVDIKANGAVQKG-MPHKYYHGKTGIVYNVTKS-SVGVIINKVVGHRYLEKRVNLRVEHIKHSACRQEFLNRVKKEAKANGQLKRQPAKPRGSRII-TPQTLAPVPYETFI Plicr1 HSFGYRARTRDMFKRGFKEHG-SIKLSTYLITYRVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPS-AVGVIVYKVVGNRYLEKRVNLRVEHIRHSKCRQEFLDRVHREAKAKGTLKRVPALPREAHTV-SAQTIVPVRYETTI Polpo HSYGQRSGTRHKFARGFRQHG-LLKTTTFLRTFRLGDIVDIKASGNVHKG-MPHKYYHGRTGRVWNVTPR-AVGVIVNKRVGPRYIAKKIHVRIEHVRPSNSMAANKKAIAIKARKAGVLPVLPAQPKTGFFV-NLQTITPLRYELLF Pucgr2 HSFGYRGRTRDMFKRGFKEAG-QIKLSTFLKVYRVGDIVDIKANGAQQKG-MPHKYYHGRTGIVYNVAPR-AVGVIVYKVVGNRYLEKRVNLRIEHVKHSKCRDDFLRRVKKEAKEKGQLKRLPAGPREARTI-SPVTLAPLPYDTTI Punst1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 HSFGLRARTRHMFSRNFREHG-VIPLSTYLKTYKVGDIVDIKANAAVQKG-MPHKFYHGRTGIIYNVTKS-SVGVIVHKVVGNRYIEKRVNVRVEHIRHSKCRQEFLDRVKKEAKAAGNLKRLPAQPRDARHV-SPQTIAPIPYETLI Rhoto1 HSFGMRARTRDMFKRDFKSKG-MIPLSTYLKEYRVGDIVDIKANAAQQKG-MPHKYYHGRTGVVYNVTPS-AVGVIVYKVVGNRYLEKRVNIRIEHIKHSKCRDDFLNRVKKEAKAKGVLKRLPAAPRESRTV-SPQTLAPIPYDTTI Rozal11 -----------------------------MKVFKVGDIVDIKANGSIHKG-MPHKYYHGKTAVVFNVSKR-AVGVIVNKRVGGRYIEKRVNIRIEHVKHSKCRDDFLARMIKEAKVKGVVKRQPKGPRPAHFI-SPTVISAVPYEILL Sacce1 KSHGYRSRTRYMFQRDFRKHG-AVHLSTYLKVYKVGDIVDIKANGSIQKG-MPHKFYQGKTGVVYNVTKS-SVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVRAEAKAQGQLKRQPAQPRESRIV-SPQTLAPVPYETFI Salro NTTGLRRGTRYMFARPFRGHG-AVGLKTYGAVYKVGQYVDIKGNGAYSVG-LPHKSYHGKTGRVYNVGKR-ALGIVVNKRIKNRYVQKKINVRIEHVKHSKCRDDFLRRRRAEARAAGSLKRKPAGPRPAHFV--AQELRPLKYEFLA Schco3 HSFGYRARTRDMFKRGFKDHG-PVKLSTYLINYRVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPH-AVGVIVYKVVGNRYIEKRVNLRVEHVKHSKCRQEFIDRVRTAAKEKGNLRRQPTLPREAHTI-TPQTMRPVPYETYI Schpo1 HSYGIRARTRYTFQRGFREHG-QIRLSTYLKTYKVGDIVDIKVNGAVQKG-MPHKYYHGKTGVVYNVTQS-SVGVLIYKVVGNRYMEKRVNVRIEHVKHSKCRQDFLDRVRKEAKAQGQLRRQPAPPAKAHFV-SPVTLHPVAYDTTI Sorma HAAGLRAGTRYAFSRNFREKG-MIRLSTYLKQYN-----------------MAHKVYHGKTGVIYNVTKS-AVGIIIYKKVKHRYLEKRINVRIEHIQPSRSREGFLRRVKKQAKAEGHLKRQPLQPREARTI-SPETVAPVAYETTI Sphar RTKGVRAGTRDMFSRGFRQKG-PEKLSTYLFCYKVGDIVDIKVNGAIHKG-MPHKFYHGKTGIVYNVSRT-ALGVIMNKQVGNRIIKKRINVRVEHLKHSKCREEFLVRKKAQGRVDGDTKRYPKQPLPAHTV-KLSRISAMPYAGLE Spipu1 HSFGLRARTRHLFSRDFRAKG-PVKLSTYLKTYKVGDIVDIKANGAIHKG-MPHKFYHGKTGIIYNVTKS-SVGIIINKQVGNRYIEKRVNIRVEHIKHSNCRLDFLRRVKKEAKEKGNLKRQPVGPTKAHHV-SPTTISPVPYEALV Sporo1 HSFGMRARTRDMFKRDFKSKG-MIPLSTYLKVYRVGDIVDIKANAAQQKG-MPHKYYHGRTGIVYNVTPS-SVGVIVYKVVGNRYMEKRVNLRVEHVKHSKCRDDFLNRVKKEAKAKGVLKRLPAAPREARTV-SPQTLAPIPYDTTI Stehi1 HSFGYRARTRHMFKRGFKEHG-PIKLSTYLIPYRIGDIVDIKANAAQQKG-MPHKYYHGRTGIIYNVTPH-AVGIIIHKVVGNRYMEKRVNIRVEHIRHSKCRQEFLDRVHQAAKAKGTLKRFPILPREAHTVKAPQTIVPVRYETTI Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------- Thetr HHRGYRMGTRHMFSRGFRKHG-NIGLKTYLQQYKIGDFVDIKVNAAQHKG-MAHKFYHGRTGRVFNVDKR-GVGVIVNKLVRNRILRKKISVRIEHIKPSKCRDEFVNRVTSAAKARGHPKRQPAGPREGFTV-KVEDIAPLAYENLF Treme1 HSFGSRARTRHMFRKGFKDHG-PPSMTTYLKTYRVGDIVDIKANSSQQKG-MPHKYYHGKTGVVYNVSPR-GVGVICYKIVNGRYLEKRVNVRVEHVRHSKCRQEFLDRVKAEAAEKGVLKRLPAQPREARTV-SPLTLSARAYETTI Trire2 HSYGKRAGTRYAFSRDFRRKG-MIALNTYLKVYHVGDIVDIKANGAVQKG-MPYKVYHGKTGVIYNVTKS-AVGIIIYKKVKHRYIEKRINVRIEHIQPSRSREDFIKRVKKQARADGQVKRQPALPRDASTV-SPETVTPLAYETTI Umbra1 HSYGIRARTRHMFSRKFREHG-SIPLSTYLKTYKVGDIVDIKANAAVQKG-MPHKFYHGRTGIVYNVTKS-AVGVIVYKRVGNRYMEKRVNIRVEHVKHSKCRQEFLDRVRKEATEAGVLKRLPVQPREARHV-SPETITPVAYETLI Ustma22 HSFGYRARTRHLFARKFRQHG-PIKLSTYLRPFHAGDIVDIKANAAEQKG-MPHKYYHGRTGVVFNVAPR-AVGVIIYKVVGNRYIEKRVNVRIEHVKHSKCRDDFLQRVKKEAKAKGQLKRLPAAPRTAHTI-SPETLAPQAYDTYI Walse1 HSFGLRARTRHLFSRNFKEHG-PIRLETYLTPYKVGDIVDIKANPGEQRG-MPHKFYHGRTGIVFNVAPR-AVGVIVYKVVRSRYIEKRVNIRIEHVKHSKCREEFLRRVLTDAKAKGNLKRQPAQPRQGHIL--PETIAPIAYDTYI Zygro1 -----------MFQRDFRRHG-ALPLSAYLKVYKVGDIVDIKANGAIQKG-MPHKVYQGKTGVIFNVTKS-AVGVMINKVVGGRCIQKRVNVRIEHIKHSKCRQEFLQRVRAAAKASGQLKRQPAGPRPAHVI-SPQTLAPVPYETYI [Cluster1201.fasta_al_trimmed; alignment length = 102] Allma1 VKTFTLRSLNKAELNKQLDELRRELLALRVKQQSNQARVLTVINQNTKLRAAYAKKYKPLDLRAKRTRALRRALTPAEKAIVTVKAAKKAKHFPQRKFAVLA Ashgo11 VKAFELRTKSKEQLEQQLISLKQELAALKVQKLSRPSRVLTVINQNQRVRELYKKKYQPKDLRAKKTRALRRALTKFEAAQITEKQRKKQIAFPQRKYAIKA Aspfu1 VKAGQLWGKSKEELSKQLEELKTELSQLRVQKIAAGARVLTVINANQRLRLFYKKKYTPLDLRPRLTRALRRRLTKHEATLKTEKQRKKEIHFPQRKYAVKT Aurde31 VKAGELRGKTKADLVKQLEELKGELLELRVQKIAGGSRVLTVSNAKARLREFYKKKYLPLDLRYKKTRAIRRRLTKHEKALKTEKQHKKDIHFPLRKYAVKA Batde5 VKAYELRTKDKEELTAKLADLKQELLSLRVQKISNGNRVLTVMNQTQLLRLFYKRKYLPLFLRPKQTRAIRRRLTAEELSLKTVRQKKKDAHFPLRKYAVKA Botbo1 VKAYELQSKSKPDLAKQLAELKTELSSLRVQKIAGGSRVLTVTNQKARLREFYKKKYLPLDLRPKKTRAIRRRLTRHEKSLKTLKQRKRDIHFPTRKYAVKA Botci1 VKTGQLWSKNKADLAKQLGELKTELGQLRTQKIAGGSKVLTVINANQRLRLFYKKKYLPLDLRSKQTRAIRRRLSKHEKELQLEKTKKRSMHFPQRKFAVKA Caeel LKCKSLRGEKKDALQKKLDEQKTELATLRVSKVTGGARLLTVINQTQKLRKFYAHKYKPIDLRLKKTRAIRRRLTAHELSLRSAKQQAKSRNQAVRKFAVKA Canalb1 VKTFELRTKSKEQLESQLVELKQELATLKVQKLQRPSRVLTVINLNQRVRAFYAKKYIPKDLRAKKTRALRRKLTKFEASQETEKARKQRIAFPQRKFAIKA Cangl VKAYELRTKSKEQLENQLLSLKKELAELQVQKLSRPSRVLTIINEQQRVRQLYKKKYQPKDMRAKKTRALRRALTKFEATRVTEKQKKKQIAFPQRKYAIKA Capow LRAYELRTKSKAELEDQLKSLKTELASLRVTKVTGSAAVLTVMNQTQRLRKHFAKKYLPTDLRVKKTRAIRRQLNQHERSQVTIREAKKRTHFPLRKYALKA Catan2 VKTFELRTKSKAELSKQLDDLRRELLSLRIKQQSGQSRVLTVINQQTKVLKEYAKKYIPIDLRAKKTRAIRRALTPAERKIKTTRALKKAKHFPQRQFAVLA Cioin IKAKELRGKSKDELLKQLNDFKQELSTLRVAKVTGGARVLTVINQTQKLRKLFKKKHKPKDLRPKKTRALRRRLNKHEESLKSVKALKKARLYPQRQFAIKA CocheC53 VKTAQLWNKSKDELASQLADLKSELIQLRTAKVTGGSKVLTVINANQRLRLFYKKKYTPLDLRPKQTRAIRRRLTKHEASLVTEKQKKKQTHFPQRKYAVKA Coere1 VKASELRDKSQAELTQTLDQYKRELLDLKVQQVAGAARVLTVITQQNRVRAEYAKKHIPKDLRAKKTRALRRVMTQHELSRKTIRQHKKDQHFGPRQYAIKA Conco1 VKAFELRTKSKEQLQAQLDELKQELANLRVQKVTNPGRVLTVLNSVNRLRELYNKKHLPLDLRAKKTRAIRRQLTAEELARKTLKQKKKLSAFPQRKYAIKA Conpu1 VKAYELQSKTKNDLKKQLDELKNELLTLRVQKVAGGSRVLTVMNQKTRLRQLYKKKYLPLDLRPKKTRAIRRRLTKNEAASKTEKQRKKDIHFPLRKYAVRA Copci VKAYELQSKSKPDLAKQLADLKNELLTLRVQKIAGGSRVLTVTNQKARLREYYKKKYLPLDLRPKKTRAIRRRLTKHEASLKTLKQQKKELNFPTRKYAVRA Croqu1 VRAHELVAKSKADLTKQLEELKVELVGLRVQKVVGGNRVLTVIQSKTRLREFYKKKHQPLDLRPKKTRAIRRRLTKYEQHLKTEKQKKRDIHFPKRKYAVKA CryneH991 IRAFELQSKSKQDLLEQLTELKTELASLRVQKIAGGSRVLTVINQKQRLREFYKSKYLPLDLRYKKTRAIRRRLTTKEASAITEKQHKKNVHFPKRKIALKA Crypa2 IKAGQLWSKNREDLTKTLGELKTELGQLRIQKIAS-SRVLTIINAKQRMRLFYKKKYLPLDLRPKQTRAIRRRLSAEDASRKLEKTKKRSQHFPQRKYAIKA Debha1 VKTFELRTKSKEQLEKQLVELKQDLANLKVQKLQKPSRVLTVINLNQRVRAFYAKKYQPKDLRAKKTRAIRRQLTKFEAKQITDKARKQKIAFPQRRFAIKA Dekbr2 VKTYELRTQSKQELEDKLVELKKELAALRVQKLNRPSRVLTIINEQQRVRAFYAKKYIPKDLRAKQTRAIRRRLTKSEKNLKTTKAKKAAIAYPARDFAIKA Dicdi TKAFELRTKNKTQLLEHLKELRTELSSLRVAQVKSPNRVLTVFNQTQKLRAVYSSSKIPTDLRYKKTRAIRRRLTNKQSKVVTLRVSKTATNFPQRVFAVKA Dmel VKCSELRIKDKKELTKQLDELKNELLSLRVAKVTGGARVYIVMHQKQKLRKVFKKKYKPLDLRKKKTRAIRKALSPRDANRKTLKEIRKRSVFPQRKFAVKA Enthi --------MSKNDMNAKLIELKGELANLRTAKVTGGARLLTVMNTQRMLRKYYKAKYVPKELRPKTTRKERRQLTKAQLNLKTVKAAKKAQHFPARKFFVLA Falba NSAKALRSLDKDQLQKELEIAKKELARFRVSKVAGTGRINTVITQNIRTRKAFL-KRMPHDLRAKKTRAIRRALPAHLKEKKTLRAQKKAAHFGQRLYALKA Fomme1 VKAYELQSKSKNDLSKQLKELKDELLSLRVQKIAGGSRVLTVTNAKQRLREFYKKKYIPLDLRKKQTRAIRRRLTPNERKKKTLRQRKKEIHFPIRKYAVKA Fusgr1 VKAGELWNKSKDDLTKQLAELKTELGQLRIQKVAS-SRVLTVINAKQRLRLFYKKKYAPLDLRAKQTRAIRRRLSPDEKSRVLEKTKKRTVHFPQRKFAIKA Galma1 VKAYELQSKSKNDLSKQLNELKNELLTLRVQKIAGGSRVLTVMNQKARLREYYKKKYIPLDLRPKKTRAIRRRLTKHEASLKTLKQTKKDKNFPIRKYAVKA Ganpr1 LKTYELRNKTKADLTKQLDELKQELSSLRVQKVAGGARVLTVISQTQRLRIFYQKKYLPLDLRAKKTRAQRRRLTRFEESRKTERQIKKERHFGQRKYAVKA Gloin1 VKAYELRNKNKAEVNKQLEDLKQELAGLKVQKIAGGARVNTVISQNQRLRKAIKKKYKPLDLRPKKTRAIRRRLTKYEVNKRTKRAHEKAIHFPQRKYAVKA Hisca1 VKTGQLWGKSKDELTKQLDELKTELGQLRVQKIAGGAKVLTVINANQRLRLFYKKKYLPLDLRPKQTRAIRRRLSKHEAALKTEKEKKKLMHFPQRKYAVKA Klula1 IKAYELRTKSKDQLEQQLVELKKELAELKVQKLSRPSRVLTVISQNQRVRELYKKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA Lacbi2 VKAYELQSKSKNDLSKQLLELKNELLALRVQKIAGGSRVLTVMNQKARLREYYKKKYLPLDLRPKKTRAIRRRMTKHESSLKTLKQRKKDLNFPIRKYAVRA Lenti61 VKAYELQSKSKNDLSKQLTELKTELLALRVQKIAGGSRVLTVMNQKQRLREFYKKKYLPLDLRPKKTRAIRRRLTKHEASLKTLKQRKKDIHFPIRKYAVKA Malgl1 VRTQDLQNKSKADLLNQVAELRKELLQLRVQKVAGGARVLTVINLKQRMREFYKKKFQPLDLRPKKTRALRRKMTKYEVSQRTERKHKKDVHFGVRRYVLKA Mellp23 VRAHELVAKSKADLTKQLEELKTELVALRVQKVVGGSRVLTVIQAKTRLREFYKKKYQPLDLRPKKTRAIRRRLTKHEKHLRTEKQKKKDIHFPKRKYALKA Mnele VKAPAMRAKSKDELLKQLEDLKTELSTLQVQKVTGGARCHTVLRANQRLRKFYQKKYIPLDLRPKKTRALRRQLTAHEASIKTKRQQKKDAHFSQRVFAIKA Monbr AKAYKLRALSKDDLLKTLQEYKAELAGLRVEQITNGTVAKTVINLKTRLRKHYKAKYVPLDLRVRKTRAQRRALTKHERAQKTVRQQKRDAHFARKVYAVKA Morel2 VKAYELRTKNKAELTKQLEELKQELASLKVQKVAGGSRVMTVITQTQRLRLFYQKNFLPLDLRVKKTRAIRRRLTKHEASVKTVKQQKKDTHFPLRKYAVKA Mucci2 VKAFELRNKNKAELLKILDEQKQQLANIRVQKVAGGRRVLTVINQTQRLRLFYQKRFTPLDLRVKKTRAMRRALTPFEKSKKTVREQKKLAHFPLRKYAVKA Mydma VKAHELRGKKKEELLHQLNELKTELQQLNVNKVTGGARVLTVISQSQRLKKFYAKKYKPLDLRSKKTRAMRRALTKHEASLKTVRQVKKLRHFGIRKYAVKE Neucr2 VKAGALWSKNKDELTKQLGELKTELGQLRIQKIVS-SRVLTIINAKQRLRLFYKKKYLPLDLRAKQTRAIRRRLSKEDASRVLEKTKKRTTHFPLRKFAVKA Orpsp11 ------------------------------------------------------------------------------------------------------ Pench1 VKAGQLWGKNKDELATQLEELKLELNQLRVQKIASGARVLTVINANQRLRLFYKKKYLPLDLRPKLTREIRRRLTKHERTQTTDKLRKRAIHFPQRKYAVKV Phybl2 VKAHELRNKNKAELLKVLDEQKQELASLRVQKVAGGSRTLTVINQTQRLRLFYQKKLIPIDLRVKKTRALRRALTPYERSLKTVKYQKKQAHFPMRKYAVKA Picst3 VKTFELRTKSKEQLSQQLVELKKELANLKVQKLQKPSRVLTVINLNQRVRAFYAKKYQPKDLRAKKTRAIRRQLTKFERSQETEKARKQRIAFPQRKFAIKA Plicr1 VKAYELQSKSKNDLGKQLVELKGELLALRVQKIAGGSRVLTVINQKTRTREFYKKKYLPLDLRPKKTRAIRRRLTKSESSAKTLKQKKKDVHFPIRKYAVKA Polpo IKAHELRKQKKTELLEQLNTLKTELSSLRVNQVKAAARVLTVFNTQRKLRTYYKRNQLPTDLRQKKTRAIRRRLTTAQQNAVPVKVLKQRQHFSPRVFAVKA Pucgr2 VRAHELVTKSKADLTKQLEELKVELVGLRVHKVVGGSRVLTVIQSKTRLKQLYKKKHLPLDLRAKKTRAIRRRLTKHEKNLKTEKQKKRDIHFPKRKYALKA Punst1 VKAYELQSKSKNDLAKQLTELKQELLTLRVQKIAGGSRVLTVMNAKQRLREFYKKKYLPLDLRAKRTRAIRRRLTPSEKKAKTLKQKKKDTHFPLRKYAVKA Rhior3 VKAFELRNKNKAELLKILDEQKQALANVRVQKVAGGKRVLTVINQTQRLALFYHKKYVPLDLRVKKTRAMRRALTPFEKSKKTLRQQKKEAHFPLRKYAVKA Rhoto1 VRASELQSKKRDELLKQLEELKTELVSLRVQKVTGGNRVLTVINAKTRLRELYKKR-LPLDMRAKKTRAIRRRLTRHERTQTTERQHKKQVHFPKRQFLVKA Rozal11 VKPHELRTKSKEELFKTLDDLKRELSSARVQKVSANNRVLTIINEKQRLRLYYKKKYYPLDLRPKKTRAIRRRLTEFEKSQETERQRKQRIHFGKRVFAVKA Sacce1 VKAYELRTKSKEQLASQLVDLKKELAELKVQKLSRPSCVLTVINEQQRVRQLYKKKYQPKDLRAKKTRALRRALTKFEASQVTEKQRKKQIAFPQRKYAIKA Salro AKAKQLRQKTKAEMLKQLDDYKAELASLRVEQVTGNSVVKTVLHEATRVRKHYAAKYKPLDLRRKLTRAMRRRLTKREANAKTARQIKRERAFPKLVYAVKA Schco3 VKAYELQSKSKNDLSKQLLELKNELLTLRVQKIAGGSRVMTVMNHKARTREFYKKKYLPLDLRPKRTRAIRRRMTKHELSLKTLKQTKREQNFPRRKYALKA Schpo1 LKTFELRKQSQENLAEQLQELRQELASLRVQKIAGGSRILTVINESNRAREAYKKKYIPLDLRQKKTRAIRRALTPYEQSRKTLKQIKKERYFPLRKYALKA Sorma VKAGALWSKNKDELTKQLGELKTELGQLRIQKIVS-SRVLTIINAKQRLRLFYKKKYLPLDLRAKQTRAIRRRLSKEDASRTLEKTKKRATHFPLRKFAVKA Sphar VKAHELRSKKPDELEAQLTQLKTELANLRVAKVTGGATVLTVITQTRRLRAHYKKKYAPLDLRVKKTRAIRQRLSKADASRKTLSAQKKAMHFPMRKYAVKA Spipu1 VKTYELRNKTKADLTKQLDELKQELASLRVQKVAGGARVNTVISQTQRLRIFYKKKYIPLDLRPKKTRAIRRRLTAFEATRKTVRQQKRETHFPLRKYAVKA Sporo1 VRASELQSKKRDELLKQLDELKTELVSLRVQKITGGNRCLTVINQKTRLRELYKKK-LPLDLRAKKTRAIRRRLTKAIRSLTTERAHKKAIHFPKRQYIVKA Stehi1 VKAYELQSKSKNDLTKQLAEQKTELLNLRVQKIAGGSRVLTVINAKQRLREFYKKKYLPLDLRTKKTRAIRRRLTANEKSKITVKQHKKNIHFPLRKFAVKA Tapde11 ------------------------------------------------------------------------------------------------------ Thetr VKAHLLRNENKEELEKQLAQYRNELAQLRVAKVTSGSRVLTVISQKKKLRKFYASKYKPLDLRPKKTRAIRQALTYKQKNLKTNRVAKRAMQYPDRVFAVRA Treme1 IKAFELQSKSKADLLTQLTELKTELARLRVQQISGGGRVLTVINQKQRLREFHKSKYLPLDLRHKKTRAIRRQLSKKEASAVTERQHKRQIHFPQRKYALKA Trire2 VKTAQLWGKNKEELAKQLSELKAELGQLRIQKVAS-SRVLTVTNATQRLRLFYKAKYLPLDLRPKQTRAIRRRLSPEDKARVLEKTKKRNTHFPQRKFAIKA Umbra1 VKAHELRNKNKAELTKQLDDLKQELASLRVQKITGGARVLTVINQTQRLRLFYKKKYTPLDLRTKKTRAIRRRLTKVEANKKTVKQQKKLAHFPQRKFAVKA Ustma22 VKTFELQSKSKTDLTKQLEELKTELLNLRVQKVAGGSRVLTVMNQKQRLREFYKKSQIPLDLRAKKTRAIRRKLNQHERTRITERQHKREIHFANRKYVLKA Walse1 VRAHELQSKNKTDLLNQLHELKGELVQLRVAKVAGGSRVLTVINQKQRVAEAYKKR-IPLDMRHKKTRAIRRRLTPKEQNAKTVRQHKREIHFGRRKFAIKA Zygro1 VKPYELRTKNKEQLQSQLVDLKKELAELKVQKLSRPSRVLTIINEQQRVRQLYKKKFQPKDLRPKKTRALRRALTKHEASQVTLKQRKREINFPQRKFAIKA [Cluster1223.fasta_al_trimmed; alignment length = 168] Allma1 NNQLPNQHFRKNWQIRVKTWFNQPGQKKARRVTRAAKAARIAPRPVLRPAVRCPTVKYNRRLRAGKGFTLDELKAAGVNRKE-AHGLGISVDFRRKSRSEEALSLNVQRLKTYKAKLIVFPKKAGKAKKGDRAITAEEAYVALRKARTLARYNGIRTKRAAEKAAAEA Ashgo11 NLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAAKAAKIAPRPLLRPVVRAPTVRYNRKVRAGRGFTLAEVKAAGLTAAY-ARTIGIAVDHRRQNRNQEIFDLNVQRLKEYQSKIIVFPRKGAAPAA--RAVED--AYRTLRLARSEKKYHGIREKRAREKAEAEA Aspfu1 GN---PDYFHKDWQRRVRVHFDQPGRKHRRREARLAKAAAVAPRPVLRPVVRCPTVKYNRRVRVGRGFTLAELKEAGIPKKL-ARTVGIAVDHRRVNYSKESLVANVARLKDYKARLILFPRKSGQFKKLDTEVKRDEAYRRLREARSEARYKGIREKRAKA-KAEEE Aurde31 NNVLPANHFRKDWQRRVKTWFNQPGRKLRRRTARQAKAALLGVRPLLRPAVRAPTVRYNTKLREGRGFTLAELKEAGISRKA-ARGVGIVVDHRRRNLSAEGKALNVERLKAYKARLVVFPRDAKKPKKADRKITAEEAYRALREARSEARYAGIRKIRKAKKEEEEA Batde5 NNQLPNQHFRKDWKIHVRTWFDQPGKKLSRRVKRVKKAAKIAPRPILRPAVRCPTVRYNTKLRAGRGFSLEELKEAGISRHF-ARTVGISVDHRRRNRSVESLQGNVQRLKEYQSKLIVFPKKANKPKNGDRKITGTPAFDTLIKARSDKRMFGMREKLAKEQAEEE- Botbo1 NNVLHANHFRKDWQRRVRTWFDQPGRKLRRRQARTAKSAALGARPILRPAVRGQTVRYNTKIREGRGFTLAELKEAGVGRKE-AKGLGIVVDHRRRNLSEEGKKLNVERLQEYKSRLIVFPRNAKKPKKGDRKITDEEAYRTLREARAFKRHEGARKVRIQKREEEEA Botci1 NQQIAHNHFRKDWQRRVRVHFDQPGRKLRRRNARLAKTAAVAPRPILRPVVRCPTIKYNRRVRAGRGFTLAELKEAQIPRKL-APTIGISVDARRQNLSVESLKANVDRLKSFRARLILFPRKLGQPKKGDSEINKSDAYRKLRVARSDARLAGKREKRAKD-AADEA Caeel NQMLGNAHFRKHWHKRIKTWFDQPARKLRRRQNRQAKAVEIAPRPVLRSVVRCPQKRYNTKTRLGRGFSLQELKAAGISQAQ-ARTIGIAVDVRRTNKTAEGLKANADRLKEYKAKLILFPKKASAPKKGDRQVTDAEIFRLLRKERADKKYRGKREKRAREAAEENK Canalb1 NLPLLNNHFRKHWQERVRVHFDQAGKKASRRQSRLRKAAKIAPRPILRPVVRAPTVKYNRKVRAGRGFTLAELKAVGIAPKY-ARTIGISVDHRRQNKSQETFDANVARLQEYKSKLVIFDKKTKASEVA-RAVEV--AYRTLRLARNEKKYKGIREKRAKEKAEAEA Cangl NLPILKNHFRKHWQERVKVHFDQAGKKESRRSARVAKAAKIAPRPLLRPVVRAPTVKYNRKVRAGRGFSLAEIKAAGLTAAY-ARTVGIAVDHRRQNRNQETFDLNVQRLKEYQSKLIVFPRKGKAPET--RAVED--AFRTLRLARSDKKFKGIREKRAREKAEAEA Capow NNVIANAHFHKDWQHLVRTWFDQPGQKKSRRQARTAKAVKVAPRPVLRPIVHAQTFRYHTKIRGGRGFTLEELKEAKINPKF-AQTIGICVDHRRVNRSLESLQANVQRLKEYKSKLVLFPRKTKAPKKADRAITAEDVYNILRVARADARMRGIREKKKREAAEEAK Catan2 NNQLPNQHFRKDWKIRVKTWFNQPGQKKARRVARAAKASVIAPRPVLRPAVRCQTAKYNRRIRAGKGFTFEELKAAGINRKE-AATIGISVDFRRKNRSEEGLAANVQRLKTYKSKLVLFPKKGAK-----RAITEEEAYVALRKARTLARYHGIRAKRAAAKAAAEA Cioin NNVISNNHFHKKWQTRVKTWFNQPARKYRRHQKRIIKARTVAPRPTLRPVVRCPTFKYNTKQRFGRGFTLEELKAAGINRYF-AATIGIAVDHRRRNKSTESLQMNVQRLKEYKSKLILFPKKLSNPKKGDRAITDAEVFQSLRMARSNAKLFGIRAKRKKEKEEAAN CocheC53 NQQIQKNHFHKDWQRYVRVHFDQPGKKKSRRNARVAKAAKVAPRPVLRPIVRCPTIKYNRRVRPGRGFSLAELKAAGIPRKF-ARTIGISVDPRRQNLSEEGLKANVERLQEYRKRLILFPRRNGKTKNGD-TVQLEEAYRKLRDSRAEARYVGAREKRAKA-KAEEA Coere1 NKQLPNVHLRKEWDLRVRTWFNQPGRKLRRRRARVAKAARIAPRPTLRPAVRCPTVKYNRKVRVGRGFTLEELKAAGISAKY-AATVGIAVDYRRRNRSEESLSLNVQRLKAYLAKLIVLPRNAKK-----RAVADEEAFVTLRQVRGDYKSHGVAQKRKAELKEKKA Conco1 -----------------------------------------------------------MKVRAGRGFTFDELKAAGINRKE-ARSIGIAVDHRRRNRSEESLQRNVERLQLYKSKLIVFPRRAGKAKKGDRAITSEEAFQTLLNLRSDLRQAGNRAKIAKAKAEEEA Conpu1 NNVLHANHFRKDWQRRVRTWFDQPGRKLRRRTARKEKAASLGVRPLLRPAVRGQTVRYNRKIREGRGFTLGELKEAGINRKQ-ARTVGIVVDHRRRNLSEEGKQLNVERLKAYKEKLVVFPRKTGKPKKGDRKITDEEAYKTLRVARADARYEGIRKVRAAKKEEEEA Copci NNVLHGNHFRKDWQRRVRTWFDQPGRKLRRRNARKAKAAALGVRPLLRPAVRAQTVRYNRKIREGRGFTLAELKEAGIGRKE-AKSVGIVVDHRRRNLSEEGKKINVERLQEYKSRLIIFPRKAGKPKKGDRKITDEEAYRTLRDAQAWQRHEGARKVRAAKREEEEA Croqu1 NNVLHKNHFRKDWQLRVKTWFDQPGAKKRRRNARQAKAAAAGVRPTLRPAVRCQTIRYNRRVRSGRGFTAAELAAAGIRRKE-ALSIGIPYDHRRRNKSEEGVALNAERLLAYKERLILFPKNPKKPAKADRAITAEEAFRALRQARTNQRQAGVWKVRKQKKEEEEA CryneH991 NNQLQKNHFHKDWQRRVKTWFDQPGKKKSRRVARSKKALASGAAPLLRPAVRCPTQRYNIRIREGRGFTTSELKLAGIRRKE-ALSLGISVDPRRRSKSEEGQKLNVERLKEYKSRLVVFPKKAGKPKAGDRAITDEEAFTTLRLARAAQRNEGQRKKRLAEKEAAEK Crypa2 NQTIVKNHFRKDWQRRVRCHFDQPGKKASRRSARKAKAAAVAPRPILRPVVRCPTVKYNRRVRAGRGFTLAELKAAGIPRLY-APTIGISVDARRQNLSEESLAANVERLKAYTARLILFPKKSNKPKKGDKTIKTSEAYRKLR------------------------ Debha1 NLPLLKNHFRKHWQERVKVHLDQAGKKASRRDHRLTKAAKIAPRPILRPVVRCPTIKYNRKVRAGRGFTLAELKAVGLSAKY-ARTIGISVDHRRQNRSEETFEANVARLQEYKSKLVVFDKNTKAAEAA-RAVEQ--AFRTLRLAKSDKKYKGIREKRTREKAEAEA Dekbr2 NYVLQKNHFKKHWQRRVRVHLDQAGQKLSRRNARAAKAAAVAPKPVLRPVVRCPTLKYNRKVRAGKGFTFAELKAAKLDPKY-AQTVGIAVDHRRVNKSTETFDANVERLELYKKSLIVF-KKGEKPTA--RAVEV--AYRTLRLARSKKRYLGIREKRAAERAAAEA Dicdi NKVLSNDHFRKHWQMRVRTWFNQPARKIRRRNNRIEKAAKVFPRPILKPVVRGSTIRYNMKVRAGRGFTLEELKAAGLTAQY-ARTIGIAVDTRRVNKTQQSLTLNTQRLKNYQSKLVLFPRKVNAPKKGERKPTEAEAYATLKAADSKAKTVGIRRKAAEIKAAKAA Dmel NNMIPNQHYHKWWQRHVKTWFNQPARKVRRHANRVKKAKAVFPRPALRPVVRCPTIRYHTKLRAGRGFTLEELKGAGIGANF-AKTIGIAVDRRRKNKSLESRQRNIQRLKEYRSKLILFPINEKKIRAGEREVTKDEAFATLRKARTDARLVGIRAKRAKEAAESED Enthi NQAVSNIHFCKDWRSKVHTWFKQPFRKIRRHQTRVEKAKSVFPATILKPSVHCMNQRFNYKLRLGRGFTLKELRAAKIDKNL-ARTIGIAVDPRRKESSKECLNRNAQRLTEYMNRLVVLPKEAKTKKAAECTLETKTAVAHLRKAKNVAK--AVSGIVKGQKKANNA Falba NHIIPGSHFRKHWFRNVKTWFDQPGQKKARRVARAQKAIAIAPRPVLRPAVHCQTQKYNAKVRLGRGFTLEELKLAGVCKRK-ALSIGIAVDHRRKNRSQESLDANVARLKAYKEKLIVFPKNATK-----PAVAVTTVFLLQGQLRRSVKFGGMRAKSAADKAAKQE Fomme1 NNVLHNNHFHKDWQRRVRTWFDQPGSKLRRRRARQTKATSLGVRPLLRPAVRGQTVRYNTKIREGRGFTLAELKEAGIGKKQ-ARGIGIIVDHRRRNLSEEGKKLNVERLKAYKSKLIIFPRKAGKPKKGDRKITQEEAYRVLRDLRAEARYEGRRKIRQAKKEEEEA Fusgr1 NQKLVNNHFRKDWQRRVRTHFDQPGKKSRRRTARQAKAAALAPRPVLRPVVRCPTIKYNRRVRSGRGFTLAELKEAGIPKAF-APTIGIAVDFRRQNLSEESLAANVARLKAYQERLILLPRRSNAPKKGDKEISKSDAYRTLRVARANARYEGARQKRVRD--AAEA Galma1 NNVLPANHFRKDWQRRVRTWFDQPGRKLRRRTARKTKAATLGVRPLLRPAVRAQTVRYNRKVREGRGFTHAELKEAGIGRKE-ARGVGIVVDHRRRNLSEEGKKINVERLQAYKARLIVFPRKAGKPKKGDRKITAEEAFRTLRVARANQRHEGVRKARAAKASPLFS Ganpr1 NNQLPGNHFRKDWQRRVKTWFDQPARKLRRRQARVAKAAAIAPRPVIRPAVRGQTFKYNTKLRAGRGFTLDELKAAGIRRKE-ALSIGISVDHRRKNRSEEGLALNVERLQAYKTRLVVFPRKAKKPKAGDRAVVQDKAFFRLRKTWSDTRLSGKREK---------- Gloin1 NNRIPNVHYHKDWQLHVKTWFDQPGRKKRRRLNRINKAARIAPRPVLRPAVRCPTLKYNTKLRAGRGFTLDELKEAGIRRKE-ALTIGIPVDHRRKNRSVESLQLNVQRLKTYKSKLIIFPKNAKKPKKADRPITDEEAYAVLRKARSDARLVGVREVRRKAKEEEEA Hisca1 NQTIPKNHFHKDWARRVRVHFDQPGRKHRRREARLAKAAAVAPRPVLRPVVRCPTVKYNRRVRAGRGFTLQELKEAGIPRKL-APTIGIAVDHRRVNASTESLTLNVARLKEYRARLILFPRRAGQHKKLDSEISKRDAYRKLRVARSEARLVGVREKRAKA-KAEEA Klula1 NLPILKNHFRKHWQERVKVHFDQAGKKVSRRHARASKAAKIAPRPLLRPVVRAPTVKYNRKVRAGRGFTLAEIKAAGLTPAY-ARTIGIAVDHRRQNRNQEILDLNIQRLKEYQSKIIVFPRKGKAPEA--RAVED--AYRTLRLARSDKRYKGIREKRAKDKAEAEA Lacbi2 NNVLHANHFRKDWQRRVRTWFDQPGRKLRRRTARKTKAATLGIRPLLRPAVRAQTVRYNRKVREGRGFTLAELKEAGIGRKE-ARGVGIVVDHRRRNLSEEGKKVNVERLTAYKTRLIVFPRKAGKPKKGDRKITDEEAFRTLRVARANQRHEGARKARAAKKEEEEA Lenti61 NNVLHANHFRKDWQSRVRTWFDQPGRKLRRRQARQTKASKLGVRPLLRPAVRAQTVRYNRKVREGRGFTLAELKEAGIGKKE-ARGVGIVVDHRRRNLSEEGKAVNVERLKAYKARLIVFPRNAKKPKKGDRKITEEEAYRTLRNERATARNEGKRKVREAKAVRILN Malgl1 NNLLHNNHFHKDWQRRVRVWFDQAGRKKSRRNARAAKAAALGMRPLLRPAVRGQTLKYNTKMRQGRGFTLEELKAAGIRKVE-ARSIGIPVDHRRKNRSEESLKLNTDRLKAYKERLIVFPRRTKKSK--GRAITAEEAFRTLRMARAIHRHEGARQARQAKRDEEAA Mellp23 NNVLHKNHFRKDWQRRVKTWFDQPGAKKRRRNARQAKAAAAGVRPTLRPAVRCMTVRYNRRLRSGRGFTAAELAAAGIRRKE-ALTIGIPYDHRRRNKSEEGVSVNTERLLAYKERLILFPKNAKKPAKGDRAITAEEAYRALREARTQQRQAGIWKVRKQKKEEEEA Mnele NNMVFDSHFHKDWQRYVKTWFNQAGKKKRRRTKRMEKAKAVAPRPVLRPVVHCQTIRYNARVRAGRGFTLDELKAAGINKKQ-ALSIGIAVDHRRKNRSQESLQANVLRLKEYKSRLILFPRKASKPKKGDRAITDEEAFQTMRMYRANVRLVGVREKRAKEAAEDDG Monbr NNVLPNAHFRKHWHNAVRCHFDQAGAKKRRYLARQAKAKKVAPRPTLRPVVRCPTFKYNTKQRLGRGFTLDELKAAGIATRY-ARSIGIAVDARRRNKDSDALMANVQRLQEYMSKLVVIK--GDKSEP--RAITADEVYREMRQARGIAKSAGKQQKKADEKKADEK Morel2 NNQLPGEHFRKDWQSRVKTWLDQAGRKKSRRIARVQKAARIAPRPVIRPAVRCPTIKYNTKLRAGRGFTLEELKAAGIRRKE-ALSIGVSVDHRRRNKSEESLQLNVQRLKAYKAKLIVFPRKAGKTKAGDRKITEAEAYEQHRKARSVARLHGIREARRKAKEEEEA Mucci2 NNQLPNQHFRKQWDLRVKTWFDQAGRKKSRRIARVQKAGRIAPRPILRPAVRCPTVRYNMKLRSGRGFTLEELKEAGVRRKE-ARSIGIAVDFRRRNKSNESLELNVQRLKAYKAKLIVFPRKAGKAKKGDRAITAEEAYMKLRYARSAARTLGAREKRARDKAEEEA Mydma NNVLPNGHFHKHWQNYVRTWFNQPGRKKRRRTARQKKALAIAPRPVLRPVVRCPTFKYHTKVRSGRGFTLEELKTAQIKLRF-AKTVGIAVDHRRKNKSTESLQANVQRLQEYQSKLIIFPRKQNKPKAGDRMITDEEVFRSMRVARANARLIGIRAKRVKDAEADAA Neucr2 NQQIPNNHFRKDWQRRVRCHFDQAGKKASRRVARQAKAAALAPRPVLRPIVRCPTIKYNRRTRLGRGFSLAELKAAGIPKLV-APTIGISVDPRRANLSEESLAANVERLKAYQARLVVFPRKSNKPKKADKEIPKSEAFRALRKARSDAKLIGVREKRAKDKAAAEA Orpsp11 NNQLPNQHFRKDWQLRVKTWFNQPARKVRRRLNRVEKAAKIAPRPVLRPAVRAQTLKYNSKIRAGKGFTLEELKEAGVNRNE-ARFIGIAVDHRRKNRSEESLQLNAQRLKEYMSKLIVFPKK--------RKSVTQDAYYTLRKAQSDAWLVGIREKRAKELAEKEA Pench1 NNQIQKNHFHKDWQRRVRVHFDQPGRKHRRREARIAKAAAVAPRPVLRPVVRCPTIKYNRRVRAGRGFTLAELKEAGIPKKL-APTVGISVDHRRTNYSKESLVANVARLQDYKARLILFPRKSGQFKKLDTEVKRDSAYRRLRDARAEARYQGMREKRAKT-KAEDE Phybl2 NNQLPNQHFRKQWQRRVKTWFDQAGRKKSRRVARVQKATRIAPRPVLRPAVRCPTLRYNMKLRSGRGFTLEELKEAGVRAKE-ARTIGIAVDHRRRNKSQESLELNVQRLKAFKAKLIVFPRKSGSPKKGDRAITADEAYMKLRYARSAARTLGAREKRAKDKAEE-- Picst3 NLPLLKNHFRKHWQERVKVHFDQAGKKASRRQARLSKAASIAPKPILRPVVRAPTVRYNRKVRAGRGFTLAELKAVGLTAKY-ARTIGISVDHRRQNKAQETFDANVARLQEYKSKLVIFDKKTKAAEAA-RAVEV--AFRTLRLARNDKKYKGIREKRAKDKAEAEA Plicr1 NNVLHSNHFRKDWQRRVRTWFDQPGRKQRRRTARKTKAATLGVRPLLRPAVRAQTVRYNRKVREGRGFTLAELKEAGVNRKE-ARGVGIVVDHRRRNLSEEGKAVNVERLKAYKAKLIVFPRKAGKPKKGDRKITDEEAFRTLRNARAAARHEGARKARVAKEEE--A Polpo NKVLSNTHLRKHWQMRVRTWFNQAGRKERRRNTRAEKAAAIFPRPLLKPIVRPPTQKYNIKTREGRGFTLEELKAAKLSVRY-ARSIGIAVDPRRTNISQQSLSLNAQRLKEYQSKLVLFPRKATAPKKGDRKVTEDEAYTTLRAASAKVKNSGLRKLAKEKKAAEAK Pucgr2 NNVLHKNHFRKDWQRRVKTWFDQPGAKKRRRNARQAKAAAAGVRPTLRPAVRCQTVRYNRRIRAGRGFTSAELAAAGIRRKE-ALSIGVPYDHRRRNKSEEGVSCNVDRLKAYKERLIIFPKNAKKPGKADRAITSEEAFRALRQARAAQRQAGVWKARKQKKEEEDA Punst1 NNVLHANHFRKDWQRRVKTWFDQPGRKLRRRNARKAKAATLGVRPLLRPAVRAPTVRYNRKVREGRGFTLAELKEAGIGRKE-ARGVGIVVDHRRRNLSEEGKALNVERLKAYKAKLIIFPRKASKPKKGDRKITEEEAYVTRRQQRGIARTEGERKAKIAKKEEEEA Rhior3 NNQLPNQHFRKQWDRRVKTWFDQAGRKKSRRIARVQKAGRIAPRPILRPAVRCPTVRYNMKLRSGRGFTLEELKEAGIRRKE-ARTIGIAVDHRRRNRSNESLELNVQRLKAYKAKLIVFPRKAASPKKGDRAITAEEAYMKLRYARSAARTLGAREKRARDKAEEEA Rhoto1 SSVLHRNHFRKDWQSRVKTWFDQPGKKHSRRVARQEKAAKAGLRPTLRPAVRPPTIRYNRKLRAGRGFTKAELKAAGIRAKE-ALSIGIPVDHRRRNRSEEGLKLNVERLEAYKARLVVFPKKAGKVKKGDRSITSEEAYAALRKARSDARLVGVRAEREKKKREEEE Rozal11 NNVLPNQHFRKHWQTRVKTWFDQPGKKKSRRLARMKKAELIAPRPVLRPAVRGQTVRYNMKLRAGRGFSLEELKAAGVRKKE-ARVLGISVDHRRKNRSVESLQLNIERLKAYKSKLIVFPRKAKNIKKSEKNITAAEAYETLRKAWNVARYDGIRKKRAADKAAAEE Sacce1 NLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARAARAAKIAPRPLLRPVVRAPTVKYNRKVRAGRGFTLAEVKAAGLTAAY-ARTIGIAVDHRRQNRNQEIFDANVQRLKEYQSKIIVFPRDGKAPEA--RAVQD--AFRTLRLARSEKKFRGIREKRAREKAEAEA Salro NNMLPNVHLHKHWHNSVKCHFNQAGKKRRRSLKRQSKAKQVAPRPTLRPIARCQTFKYNMRLRAGRGFTPLELKEAGLSTRY-AQTVGISVDKRRKNRSVEAFQANVARLKEYKSKLVVIRKGGKDQHA--RAITEKEVFAEMRHMRADAKLAGIRLKVAAEAAAEAA Schco3 KNVLHDNHFRKDWQRRVKTWFDQPGRKQRRRIARKKKAAALGVRPLLRPAVRGQTVRYNRKLREGRGFTLAELKEAGVGRKE-ALSIGIAVDHRRRNLSEEGKKLNVERLQAYKARLIVFPRKAGKPKKGDRKITDEEAFRSLRIARANARHEGARKARQAKKEEEEA Schpo1 KGQLPNAHFHKDWQRYVKTWFNQPGRKLRRRQARQTKAAKIAPRPVIRPAVKPPTIRYNMKVRAGRGFTLEELKAAGVSRRV-ASTIGIPVDHRRRNRSEESLQRNVERIKVYLAHLIVFPRKAGQPKKGDKPITEEAAFSTLSNERAYARYAGARAAFQKKRAEEAE Sorma DSRRP--YFRKDWQRRVRCHFDQAGKKASRRVARQAKAAALAPRPVLRPIVRCPTVKYNRRTRLGRGFSLAELKAAGIPKLL-APTIGISVDPRRANLSEESLAANVERLKAYKARLVVFPRKSNKPKKADKEINKSEAFRALRKARSDAKLVGVREKRAKDKAAAEA Sphar NNVVPNAHFKKDWQNRVQCWFNQPGRKQRRRVSRQQKAVAIAPRPVVRPAVRCPTAKYNSRMRSGRGFTLDEIKEAGLSAKV-ARTVGIAVDHRRKSRSVEALNRNVQRLKEYNERLIVFPKRAGKAKKGDRAITEEEAFYTLRMARANAKYVGVREKRAIAKAEAAA Spipu1 NNVLPNAHFRKDWQLHVRTWFDQPGKKKSRRVHRIKKAAQIAPRPVLRPAVRGQTVKYNMKLRAGRGFTLEELKAAGIRRKE-ARTIGIAVDHRRKNRSVEGLEANVQRLKEYSARLIVFPKKANKPKKGDRPIGEAPAYATLRKARSDKRLKGVREARAKAAAEEEK Sporo1 NSVLHRNHFRKDWQSRVKTWFDQPGKKHSRRLHRQAKAVKAGLRPTLRPAVRCPTQRYNMKLRAGRGFTKQELKAAGIRRKE-ALSLGVPVDHRRRNASEEGLKLNVERLEAYKTRLVVFPKKAGKVKKGDREITAEEAFRALRVARSDARLVGVRAERKRKAEEEEA Stehi1 NNVLHDNHFRKDWQRRVKTWFDQPGRKLRRRQARKAKAAALGVRPILRPAVRGQTVRYNIKIREGRGFTLAELKEAGIGRKA-ARGVGIVVDHRRRNLSVEGKQLNVERLKAYKERLVVFPRKAGKPKKGDRKITDEEAYKTLRNARAESRYEGARKARAAKKEEEEA Tapde11 NNVLPRNHFRKDWQSRVKTWFDQPGKKLRRRHARVEKASKVAPRPTLRPVVHCPTSKYNMKVRAGRGFSLEELKAAGIPRQF-AKSIGIAVDHRRQNRSQESIDANVARLNAYKSQLILFPRKHGKSKKGDRAITSEERYHDQRMERSNKRLAGKRAAAAKKAAEEAE Thetr NNQVPNAHFHKDWQNRVRTWFNQPGRKKRRRNNRLAKAARIAPRPMLRPAVHCQTIKYGRRLRAGRGFSLLELKTAGINRNY-ARTIGIAVDLRRKNSSQESVDRNVARLKEYMSRVIVFPRPGKGRRLADRAITEEDVYKTLRIERKNQRQHGIRARRAADKAAKAK Treme1 NNQLPKNHFHKDWQRRVKTWFDQPGRKKSRRSARSKKALALGAGPLLRPAVRCPTQRYNIRIREGRGFTLSELKLAGIRKKE-AKGLGIVVDHRRRSKSEEGQTVNVDRLKEYRSRLVVFPRKAGKPKKGDRAITDEEAYSTLRLARADQRHEGARKKRAEAKAADEA Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 NNQLPNQHFRKDWQRRVKTWFDQPGRKKSRRIARIQKAARIAPRPVLRPAVRCPTIKYNTKLRAGRGFTLEELKEAGVSRKQ-ALTIGISVDHRRRNKSQESLELNVQRLKAYQAKLIIFPRKAGKPKNGDRAIKAEEAFQKLRYARSEARTLGAREKRARDKAEEEA Ustma22 NNILHNNHFRKDWQRRVKVWFDQPGAKKRRRTAREAKAAKLGLRPVLRPAVRCPTLRYNTKIRSGRGFTIEEVKAAGLGKKY-ARSVGIPVDHRRRNKSEESLKLNVERIKAYQARLVVIPKLTKKNK--DRAITSEEAYETLRKARGTHRAAGKVKARIAKKEEEAA Walse1 NNVLHRNHFRKDWQSRVKTWFNQPGKKKSRRVTREKKAAALGVRPLLRPAVRCPTIRYNRKLRAGKGFSLAELKAAGIRRKE-ALSIGIPVDHRRRNLSEEGLKINVDRLTAYKARLIVFPRNAKKPAKTDRKITDAEAYRTLRNERATARYDGARKVRAAKKAEEEE Zygro1 NQPILNPHFRKHWQERVKVHFDQAGKKASRRDTRIAKAAQIAPRPLLRPVVRAPTVKYNRKVRAGRGFTFQEVKAAGLTPTY-ARTVGIAVDHRRVNRNQEIFDANVQRLKEYQSKLIVFPRNGKAPEA--RAVED--AFRTLRLARSDKKFKGIREKRAKEKAEAEA [Cluster1266.fasta_al_trimmed; alignment length = 259] Allma1 VKVVKNQVKYRRRREGKTDYYARKRLVTQAKNKYNSPKYRLVVRITNADVICQIVYSKIQGDFVLTAAYAHELPKYGIKVGLTNWAAAYATGLLVARRALKKLSLDDKYEGFVNVEP-L--DDGP-RPFKAFLDTGLARTTTGAKVFAAMKGASDGGIFVPHSEQRFPGYDREAKELDAETLRSYIFGGHVAEYMRYLEEEDEEKFKRQFSRFLAEGLTADSLEDMYTSAHAAIRAN--PEHVKSDKVKKFKRLNLKQR Ashgo11 IKSIKNQTPFRRRREGKTDYYARKRLVTQHKAKYNTPKYRLVVRFTNKDIICQVVSSTITGDIVLAAAYSHELPRYGITHGLTNWSAAYATGLLIARRTLQKLGLDETYKGVEETEA-V--EDGP-RPFKVYLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFESEELDADLLRTYIFGGHVSAYMEELADDDEERYSELFKGYIADGIEADAIEDIYTEAHAAIRAD--PSFKPTEESKKFRKLTKEER Aspfu1 ------QTKYRRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIITQIVYSEITGDKVFASAYSHELKRYGITQGLTNWAAAYATGLLLARRTLKKLGLDEQFTGVEETEA-VETDDGTRRPFKAFLDVGLVRTSTGARVFGAMKGASDGGIFIPHSENRFPGYDIESEELDAETLRNYIFGGHVSEYMETLADDDEERYRSQFAKYIENEIDAGDLEEIYAEAHKAIRED--P-FKKDEESKKYKKLSREEK Aurde31 VKLVKNQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRITNKDIICQIVYARLQGDFVLVAARSAELPRYGINHGLTNWAAAYATGLLVARRALKKLGLDEKYQGVTETEA-LDDDDAP-RPFKCFLDVGLRRTSTGARVFGALKGASDGGIYIPHSDKRFPGYDAENKSLDAEVLKKYIYGGHVAEYMESLEEEDDERFKKQFSSYLEDGIGSEDINEIYEKAHEAIRED--PTFKSSDESLKYKRLTYDQR Batde5 VKVVKNQTKYRRRREGKTDYYARKRLVTQAKNKYNSPKHRLVVRITGKDIVCQIVYSKIQGDVVMAAAYSHELPKYGIKHGLTNWAAAYATGLLIARRVLTKLNLDSKYEGCVEIEP-M--EDGP-RPFRAFLDIGLRRTTTGSRIFGALKGAVDGGLAIPYSENRFPAYSKSDKKCDTELLASYIYGGHVTEYMEYLIEEDDEAYKRQFATYIADGIEPADLEDIYKEAHNKIREN--PVAEKKEKLKSYKPMNLKQR Botbo1 VKVVKTQVKYRRRREGKTDYYARKRLVAQAKNKYNAPKYRLVIRFTNKQVIAQISYARIQGDAVLAAASSKELPRYGINHGLTNWTAAYATGLLVARRALTKLGLADKYEGVSATEA-LDDEDAP-RPFKCYLDVGLKRTSTGSRLFGALKGASDGGLFIPHSEKRFPGYDVETKALNAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFSTYLADGVGSEDIEEIYTNAYAAIRED--PTFKPTEESLKYKRLTHAQR Botci1 TKLVKNQTKYKRRRSGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIVMQIVTSEITGDKVFCAAYSHELKAYGIEHGLTNWAAAYCTGLLIARRVLKKLGMDKDFTGVEETEA-A--GDEERRPFKAFLDVGLHRTSTGARIFGAMKGASDGGILVPHSENRFPGYDMESKELDAETLRKYIFGGHVAEYMETLADDDEERYKSQFQGYIDDEIEADGLEELYQEAHKAIRED--P-FKKAEESLKFKKLTKDEK Caeel VKVIKNQVKLRRRREGKTDYYARKRLTVQDKNKYNTPKYRLIVRITNKDVVAQLAYSKIEGDVVVASAYSHELPRYGLKVGLTNYAAAYATGLLLARRHLKTIGLDSTYKGHEEVE-----EEGDRAPFKAVLDIGLARTTTGSKIFAVMKGVADGGINVPHSESRFFGFDQESKEYNAEAHRDRILGKHVADYMTYLKEEDEDRYKRQFSKFLAAGLNADNLVATYQKVHSAIRADASPAAKKAA--KRHTRLTYDER Canalb1 QKEFRTQTPFRRRQEGKTDYYQRKRLVTQHKAKYNSPKYRLVVRFTNKDIIAQIVSAHITGDVVFTAAYAHELPRYGIKYGLTNWSAAYAVGLLVARRALQKLGLDETYTGVEETEA-V--EDGP-RPFKVFLDIGLQRTTTGARVFGVLKGASDGGLYVPHSPNRFPGWDIEAEELDAELLRKYIFGGHVAEYMEELLDDDEEKYKSIFKNYIEEEIESEDVEEIYANAHEAIRAD--PSFKPTEESKKYRKLTRAER Cangl IQNLKTQTPFRRRREGKTDYYQRKRLVAQHKAKYNSPKYRLVVRFTNKDIICQIVSSTITGDIVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRALQKLGLDETYKGVEETEA-V--EDGP-RPFKVYLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFEAEELDAELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSIEDIYASAHEAIRAD--PSFKPTEESKKYKKLTKEER Capow VKVVKNQVQFRRRRQGKTDYYARKRLITQDKNKYNSPKYRLVVRFSNRDIVAQIASAKIEGDVILAAAYAHELPRYGVKLGLTNYAAAYATGLLLARRLLTKVGLADAYKGVEKVE-----EEGEKRPFQAFLDVGLARTSTGARLFGVLKGAVDGGLNVPHSTRRFPGYSAESSTYKAEAHRDRIFGKHVADYMRTLQKEDPEAYKRQFSKYIAAKIGADQVEGVYKAAHAAIRAD--PTHKSTATRKSYHKITLAQR Catan2 VKAVKNQVKYRRRREGKTDYYARKRLVTQAKNKYNSPKYRLVVRITNADVICQI------------------LPRYGVKVGLTNWAAAYATGLLVARRALKKLSLDDKYEGFVNVEP-L--EDGP-RPFKAFLDVGLARTTTGAKVFAAMKGASDGGIFVPHSEQRFPGYDRESKELDTDVLRSYIFGGHVAEYMRYLQEEDEEKFKKQFSRFIAEGLAADDLEEMYEKAHEAIRAN--PEAVKSTKVKKFKRLNLKQR Cioin VKVVKNQVKYRRRREGVTDYFARKRLVVQDRNKYNTPKYRMIVRFTNKDIITQIAYARIEGDVVICAAYAHELPRYGVKVGLTNYSAAYCTGLLLARRLLTKFGLDKIYEGQTEVED-I--DGQP-GAFRAFLDIGLARTTTGARIFGAMKGAADGGLDIPHSVKRFPGYDAESKEFNAEVHRNHIFGQHVSEYMTSLEESDEDAFKRQFSQYIKNGITADGVEEMYKKAHASIRED--PTPKAKVPKKRWNKLTKSQR CocheC53 SKLQKNQVKYKRRRQGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNKDIICQIVHSEIGGDKVFMAAYAHELKAYGITHGLTNWAAAYATGLLLARRVLKKLKIDEDFVGVEETEA-AEVDGEERRPFKVFLDVGLTRTSTGARVFGAMKGCSDGGVFVPHSENRFPGYDIEAKELDAEVLRKYIFGGHVAEYMETLADDDEERYKSQFSGYIEDDIEADGLEELYQDAHKQIRED--P-WKKVEESKKYKKLTKAEK Coere1 VKLQKNQVKYRRRREGKTDYYARKRLVVQAKNKYNAPKYRLVVRFTNTDVICQVVYAKIQGDVVLAAAYSHELPRYGIKVGLTNWPAAYATGLLVARRVLTKLGLDEQYEGFPEVEA-L--EDGP-RPFKAFLDVGLKRTTTGSKVFAAMKGASDGGIFVPHSETRFPGFDAESGELDSGVLRDYIFGGHIAEYMRLLKEEDEERYNAQFSRFIKAGVSADDLEDIYSSAHEAIRAD--PSPKLTE--KPQRPLNAKQR Conco1 QKQVKNQTKYRRRREGKTDYYARRKLVIQAKNKYNSPKYRLVVRFTNKDIVAQIVYSKIVGDVVVASAYAHELPRYGVKVGLTNYAAAYCTGLLVARRVLTKLGLADKYEGVVETEA-I--EDAP-RPFKAFLDVGLARTSTGAKVFAAMKGASDGGIFVPHSENRFPGYDAESKSLDTETLRSYIYGGHVSEYMKLLEEEDEERYKRQFSKFIEAGVGADDLEDMYKAAHKAIRDD--PSFTKKE--KNYNALNLKQR Conpu1 VKKVKSQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFSNKAVTCQIIYARLQGDFVLCAARSTELPRYGINHGLTNWTAAYATGLLCARRALAKLGLADKYEGVAETEE-LDDEDAP-RPFKCYLDVGLKRTSTGHRVFGAMKGASDGGLFIPHSEKRFPGYDPESKELDAEVLKKYIFGGHIAEYMESLEEEDDERFKKQFASYLADGVGSDDMEEIYTNAYAAIRED--PSFKPTDESLKHKRRTYEER Copci VKKQKTQVKFRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRLTNKDIIVQVVYARIQGDFILTQAHSRELPRYGIKHGLTNWAAAYATGLLAARRALTKLGLADKYEGVTETEA-LDDDDAP-RPFKAFLDVGLRRTSTGARVFGAMKGASDGGIYIPHSEKRFPGYDPESKSLDAEVLQKYIYGGHVAEYMESLEEEDDERFKKQFASYLADDIGSDDIEDIYKNAHAAIRAD--PTFKPTTESLKYKRLTLEQR Croqu1 VKLVKNQVKYRRRREGKTDYYARKRLITQAKNKYNSPKFRLVVRITNRDIICQIVHAKLQGDFVLAAAYSHELPRYGIKHGLTNWAAAYATGLLVARRALTKLGLDEKYAGVEETEA---NEEGP-RPFKAFLDVGLRRTSTGARVFGAMKGASDGGIFVPHSENRFPGYDPEAKELDADVLKSYIYGGHVAEYMEALEEEDDERFKKQFSTYLADDIGSGDIEEIYTEAHKAIRAD--PSPKPTDASKKDKKIGKVQR CryneH991 VKVQKNQVKPRRRRQGKTDYQARRGLVSQAKNKYASPKYRLVVRITNKQVICQIVYAKLQGDVVFAHATSKELPRYGIKHGLTNWTACYATGLLVARRALTKLGLADKYEGVVEIEP-LGD-DEP-RPFKCYLDVGLRRTSTGARVFGAMKGASDGGIFIPHNEKRFPGYDPESKELDAEVLQKYIVGGHVAEYMESLEEEDDERFKKQFSSYLADGVGSDDIEEIYTNAYEAIRED--PTFKPTEESLKYKKLTKEQK Crypa2 HKLVKNQTKYKRRRSGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIIMQIVTSEISGDKVFVSAYSHELRAYGIEHGLTNWAAAYATGLLIARRALKKLGIDEHFKGVEETEA-AETDDGERRPFKAFLDVGLARTSTGARVFGAMKGASDGGIFVPHSENRFPGYDVESEELDAETLRKYIYGGHVAEYMETLADDDEERYKSQFQKYIDDDVEADGLEDLYTEAHAAIRED--P-FKKYEESQKYRKLTYDEK Debha1 DQRPKSQTPFRRRQEGKTDYYQRKRLVTQHKAKYNSPKYRLVVRFTNKDIIAQIVSSQITGDLVFTAAYAHELPRYGISHGLTNWSAAYAVGLLVARRALQKLGLDETYKGVEETEA-V--EDGP-RPFKAFLDIGLQRTTTGARIFGVLKGASDGGLYVPHSPNRFPGWDIEGEELDAELLRKYIMGGHVAEYMEELMDDDEEKFRTLFKSYLADEIEAEDVEELYMNAHEKIRED--PSFKPTEESKKYRKLSKAER Dekbr2 IAH--KQTPFRRRREGKTDYYARKRLVTQNKAKYNTPKYRLVVRFTNKDIICQIISSTLKGDIVFTAAYSHELPRYGIKHGLTNWPAAYATGLLIARRALQKLGLDKTYEGVEETEA-V--EDGP-RPFKVFLDVGLQRTSTGAKVFGCLKGASDGGLYIPHSPSRFPGWDMEVEELDDELSRSYIFGNYISEYMEDLVDDDEERYNLLFKNYISEGIEADSIEDSYTDAHAAIRED--PSFKPADNSKKYRKLSKEER Dicdi VKVVKTQVQFRRRREGKTDYQQRHRLITQDKNKYNSPKYRLVARITNTDVIAQVVYSKIVGDFVLCAAYAHELPRFGVKVGLTNYASCYATGLLLARRLLAKLKLADLYKGAEKVKP-V--DDKP-RPFKANLDVGLARTSTGAKVFAVLKGAVDGGIYVPHGETRFAGYNAESKKLNAETLRGYIFGKHVASYMTLLQTEDEDAYKKIFSQYIKNGVAPKDIETIYANAHKAIRAN--PAPAAKS-TKSYKKRTLKQK Dmel VKVVKNQVKFRRRREGKTDYYARKRLTFQDKNKYNTPKYRLIVRLSNKDITVQIAYARIEGDRVVCAAYSHELPKYGIQVGLTNYAAAYCTGLLVARRVLNKLGLDSLYAGCTEVEP-V--DDGP-GAFRCFLDVGLARTTTGARVFGAMKGAVDGGLNIPHSVKRFPGYSAETKSFNADVHRAHIFGQHVADYMRSLEEEDEESFKRQFSRYIKLGIRADDLEDIYKKAHQAIRND--PTHKVTATKKRWNKLTNEQR Enthi LKVIKNQTQFRRRREGKTDYYARRKMIFQDKDKFKTPKYRVVVRITNKTVIAQIAYSEIIGDKILCAAYSHELPRYGVKLGLTNYAAAYCTGLLLARRLLQKLGMDKQFVGVSDPEE----VDER-RPFKCILDVGLARTTTGSKVFAVLKGMCDGGVYVPHSATRFAG-----AGENEEALRSRILGGHVAAYMKYLSGEDADLYKKQFGRFIAAGIAPEALENIYIEAHKKIREN--PAAEKKEEHKKYPKLTLEQR Falba LKVVKNQTQYRRRRDGKTDYYARQRLVNQDKNKYASPKYRFVVRITNNDIIAQFIYSKIEGDYVVSSAYAHELKNFGITVGLTNYAAAYAVGLLAARRLLTKLNLASIYEGTTEVEE-I--DGQP-RPFRAYLDTGLARTTTGARIFGVMKGAVDGGVAIPHSEKRLPGFDVESGEFDAEVLRKRIFGEHVAEYMELLKDEDEEAYKKQFSRFIKAGLTAESLPEVYKKAHALIRAD--PVHKAKPENKRWTKLTYDER Fomme1 VKQQKSQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNKQVIVQIVYARLQGDFVFAAATSKELPRYGINHGLTNWTAAYATGLLCARRALAKLGLADKYEGVADTEA-LDEEDAP-RPFKCFLDVGLRRTTTGARVFGAMKGASDGGIFIPHSEKRFPGFDVETKELDAEVLKKYIFGGHVAEYMESLEEEDDERFKRQFSSYLADGVGSEDIEEVYRNAYAAIRED--PAFKPTEESLKHKRLTHEQR Fusgr1 -KLVKNQTKYKRRQQGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNKDIICQIVTSEISGDKVFISAYAHELKAYGIEHGLTNWAAAYATGLLVARRALKKLGLDEDFAGVEETEA-AETDDGERRPFKVFLDVGLKRTSTGARVFGAMKGASDGGILVPHSEKRFPGYDMETKELDADTLRNYIFGGHVAEYMETLADDDEERFRSQFQKYVDDDVEAEGLEDLYTEAHAAIRED--P-FKKVEISQKYKKLTKEEK Galma1 VKKIKSQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNKDIIVQIIYARLQGDFVLTAAQSRELPRYGINHGLTNWAAAYATGLLCARRALHKLGLADKYEGVTETEV-LDDEDAP-RPFKCYLDVGLKRTSTGSRVFGAMKGASDGGIFIPHSDKRFPGYDPEGKSLDAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFSTYLADGVGSEDIEEIYTNAHAAIRED--PTFKPTEEGLKYKKLTYDER Ganpr1 VKVVKNQVKYRRRREGKTDYYARQRLVVQAKNKYNSPKYRLVVRFTNRDTIVQVIYAKIEGDYVLCSAYSHELEKYGITFGLTNWSAAYATGLLCARRLLKKLGLDTDYIGQEKVE-----ENGDKRPFQCFLDVGLARTTSGSRVFAAMKGAADGGLLIPHSESRFPGYDREAKKLDAEMLKKYIYGGHVKEYMEYLEEEDEEAYKKQFAKYIENDVGPDDLEELYNDAHAKIRED--PDPVLKDKLKKFKRKNLKER Gloin1 VKTVKNQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNTDVIVQIIYAKLDGDFVLTAAYSHELKKYGIKIGLTNWAATYATGLLAARRVLTKLGLADKYLGITEIEE-L--EDAP-RPFKAFLDVGLKRTSTGSKVFAALKGASDGGIFIPHGENRFPGYDAESKTLDTEVLRKYIYGGHVADFMRILQEEDDDKFKKQFSKFIEAGVGADDLEKVYKDAHANIRAD--PVFKPTE--KKYKRLNLKQR Hisca1 TKLVKNQTKFKRRREGKTDYYARKRLITQAKNKYNAPKYRMVVRFTNRDIITQIVTAEMTGDKVFASAYSHELKRYGIKHGLTNWAAAYATGLLLARRALKKLGLDEDFVGVEETEA-AETDEGTRRPFKVVLDVGLQRTSTGARVFAAMKGASDGGILIPHSESRFPGYDIETKELDAETLRRYIFGGHVAEYMETLADDDEERYKSQFQKYIDDDVDAGDLEEIYAEAHKGIRAD--P-FKKDEESLKYRKLTRAEK Klula1 IKDIKTQTPFRRRREGKTDYYARKRLVAQHKAKYNTPKYRLVVRFTNKDIITQIVSSTITGDIVLAAAYSHELPRYGITHGLTNWSAAYATGLLLARRTLQKLGLDETYPGVEETEA-V--EDGP-RPFKVYLDVGLQRTTTGARIFGALKGASDGGLYVPHSENRFPGWDFEAEELDADLLRTYIFGGHVSQYMEELADDDEERYRELFKGYLADDIDADAVEDIYADAHAAIRED--PAFKPTEESKKYRKLTREER Lacbi2 VKKLKSQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNRDIIVQIVYARLQGDFVLTAAHSRELPRYGINHGLTNWSAAYATGLLCARRALTKLGLADKYEGVTETEV-LDEEDAP-RPFKCYLDVGLKRTSTGSRVFGAMKGASDGGIFIPHSEKRFPGFDPESKELDAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFATYLADGVGSDDIEEIYTNAHSAIRED--PTFKPTDESVKHKKLTHAQR Lenti61 VKKVKSQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNREVIVQIVYARLQGDFVLTSARSKELPRYGINHGLTNWTAAYATGLLCARRALTKLGLADKYEGVADTEV-LDEEDAP-RPFKCYLDVGLKRTSTGSRVFGALKGASDGGLFIPHNDKRFPGYDPESKELDAEVLKKYIFGGHVAEYMESLEEEDDERFKKQFSTYLADGVGSEDIEEIFTNAYAAIRED--PTFQPTEESKKHRKLTLEQR Malgl1 -----------------------------------------------------------------------------------------------------------------------------------------------------MKGASDGGIFVPHNARRFPGYDVESKELDAEVLRNYIYGGHIAEFMESLEEEDDERFKKHFSSYLSDDIGSEDIEEIYEKAYEAIRED--PDFKPTEESKKYKKLTYEQR Mellp23 VKLVKNQVKYRRRREGKTDYYARKRLITQAKNKYNSPKYRLVVRITNRDIICQIVHAKLQGDFVLAAAYSHELPRYGIKHGLTNWAAAYATGLLVARRALTKLGLADKYAGVEETEA---NEDGP-RPFKAFLDVGLRRTSTGARVFGAMKGASDGGIFVPHSENRFPGFDPEAKELDADVLKSYIYSGHVAEYMEALEEEDDERFKKQFASYLADDIGSGDIEEIYTEAHKAIRAD--PSAQPTDASKANKKIGKEQR Mnele VKVVKNQVKYRRRREGKTDYYARKRLIIQNKNKYNTPKYRLVVRFTNKVIIAQVAYATIEGDKIVCDARSSELPRYGIKTGLTNYPASYAVGLLLARRLNQKYGLDETYTGVEEVE-----KEGERGAFYCVLDTGLSRTSSGARIFGVLKGAVDGGLDIPHSSKRFPGYNTETDENNAAAHRARILGEHISSYMQTLLDDDEDAYKRQFATYRKEGIMPDMIEGMYTKAHAAIRAD--PSPAA----KSYRRMSIQQR Monbr ----MDQVKYRRRREGKTDYYARTRLVRQEKNKYNTPKYRLIVRRTTSDVVAQIAYSRLEGDYIMAAAYSHELPQFGFKVGLTNWSACYATGLLVARRLLTKLNLADTYKGVEEVEE-A--EDKP-RPFRCYLDVGLAPTTTGSRVFGVMKGAVDGGLAIPHNHKRFPGYDAEAKEMDAEVVRDYIFGEHVANYMRELQDEDDEAFRKQFAKYIKLGVGADDIEDMITEAHEKIREN--PIIPKK-EHKSYKPLSYAQR Morel2 IKLVKNQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNADIVCQIVYAKLQGDFVLASAYAHELPKYGVKGGLTNWAAAYCTGLLVARRVLTKLGLADKYEGVSETEA-I--EDAP-RPFKCFLDVGLKRTSTGSRVFAAMKGASDGGVFIPHGENRFPGFDAEAKELDAEVLRSYIYGGHVADYMRYLEEDDDDKYKKQFSKFIAAGVEADDLEEMYQDAHNAIRED--PTHVPTEKVKNNHRLTYKQK Mucci2 VKQQKNQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNKDIICQIIYAKLQGDFVLSAAYAHELPRYGVKGGLTNWASAYATGLLLARRTLAKLGLADKYEGFAEIEA-A--EDAP-RPFKAFLDVGLARTSTGARVFGAMKGASDGGIFVPHNGNRFPGFDIETKTNDDELLRNYIYGVHVAEYMEYLEEEDEERYKKQFSTFIKAGITSDKVEDMYTEAHEAIREN--PAAQLAE--KPYRALNKKQR Mydma VKVIKNQVKFKRRREGKTDYYARKRLVTQDKNKYNTPKYRLIVRFTNKDIACQIAYAKIEGDVIVCAAYSHELPRYGVKVGLTNYAAAYCTGLLLARRLLLKFNLHETYAGQKEVES-V--SDGP-HAFRCYLDVGLKRTTTGARVFGALKGAVDGGLDIPHSTRRFPGYDDAGKALNAEVHRNHIFGKNVADYMTSLQEEDEEAFKRQFSQYIKEGVTPGTIEAMYKKCHAAIRAD--PSSKPSEKGKRWGKMSLAQK Neucr2 HKLVKNQTKYKRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIILQIVSSEITGDKVFASAYSHELKAYGIEHGLTNWAAAYATGLLLARRVLKKLGLDETFKGVEETEA-AETDDGERRPFKAFLDVGLARTSTGARVFGAMKGASDGGIFIPHSENRFPGYDMESEELDAETLKKYIFGGHVAEYMETLADDDEERYKSQFNRYIEDDLEADGLEDLYAEAHAAIRED--P-FKKAEESLKYKKLTREQR Orpsp11 IEILKEQKKWEKQKEGKTDYYARKRLVTQAKNKYNSPKYRLVVRFTNTDVIAQFVYSKIEGDYILCAAYSHELPNYGIKVGLTNWAAAYATGLLAARRVLKKLGLDTQYEGVTEVEE-N--EEGP-RPFKAFLDVGLRRTTTGSKVFAVMKGAADGGVLIPHSETRFPGYDSEEKSLDAEVLRDYIFGQHVAEYMRTLEEEDEEKYKKQFSRFIAAGVSADDLEGMYAEAHKKIRAN--PEFVKKEQLKKFKKRNLKQR Pench1 HKLERGQTKYRRRREGKTDYYARKRLITQAKNKYNAPKYRMVVRFTNRDIVTQIVYSEVTGDKVLASAYAHELPRYGIDQGLTNWAAAYATGLLLARRVLKKLNLDEQFKGVEETEA-IETEDGERRPFKAFLDVGLVRTSTGNRVFAAMKGASDGGIFIPHSERRFPGYDIESEELDAETLKGYIHGSHVSEYMETLADEDEERYKSQFIKYIENEIDAGDLEEIYADAHKAIRED--P-FKADEESKKYKPLTREQR Phybl2 IKQQKNQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNKDIICQIVYAKLQGDFVLAAAYSHELPRYGIKGGLTNWAAAYATGLLLARRTLTKLGLADKYEGVTEVEA-I--EDGP-RPFKAFLDVGLARTSTGARVFGAMKGASDGGIFVPHSGNRFPGFDIESKTNDDELLRNYIYGVHVAEYMEYLEEEDEERYKKQFSTFLKQGITSDKVEDMYTEAHEAIRAD--PVYKLTK--KPYPRLNKKQR Picst3 QKALKSQTPFRRRQEGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFSNKDIVAQIVSSQITGDVVLTAAYAHELPKYGINHGLTNWSAAYAVGLLVARRALQKLGLDETYQGVEEVEA-V--EDGP-RPFKVFLDIGLQRTTTGARIFGVLKGASDGGLYVPHSPNRFPGWDIEAEELDAELLRKYIFGGHVAEYIEELMDDDEEKYRTLFKSYIADEIEAEDIEELYTEAHAKIRED--PVFKPTEESKKFRKLTREER Plicr1 VKKVKSQVKYRRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNKEVICQIIYARLQGDFVLTAARSRELPRYGINHGLTNWAAAYATGLLVARRALTKLGLADKYEGVAETEA-LDEEDAP-RPFKAYLDVGLKRTSTGSRVFGALKGASDGGIFIPHSDKRFPGYDPESKELDAEVLKKYIYGGHVAEYMESLEEEDDERFKKQFASYLADGIGSEDMEEIYTNAYAAIRED--PTFKPTEESLKFRKLTHAER Polpo VKVIKNQVQFRRRREGKTDYQQRHRLITQDKNKYNSPKYRLVARFTNTKVIAQVIYSKIVGDFVLASAYSTELPRYGVSVGLSNYAAAYATGLLLARRLLTQLKLNDLYKGQEKVKP-V--DDKP-RPFKAFLDVGLARTTTGNKVFAVLKGACDGGMYIPHKKTRFVGYNAETKKLNAEVLKKYIFGGHVAEHMKLLQTEYEKEYKRHYSQFVKANVAPKDLEAMYTKAHAAIRKD--PSAKKAD-KKNYKKRTLNQR Pucgr2 VKVVKNQVKYRRRREGKTDYYARKRLITQAKNKYNSPKYRLVVRITNRDIICQVVHAKLQGDFVLAAAYSHELPRYGIKHGLTNWAAAYATGLLVARRALVKLGLDEKYQGVEETEA---NDEGP-RPFKAFLDVGLRRTSTGARIFGAMKGASDGGIFVPHSENRFPGYDPEAKELDADTLKSYIYGGHVAEYMEALEEEDDERFKKQFSTYLADDIGSADIEEIYTEAHKAIRAD--PSPKPTDASKQNKKITKEQR Punst1 VKKQKSQVKYRRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNKDIIVQVVYARLQGDFVLTQAHSRELPRYGINHGLTNWTAAYATGLLAARRALTKLGLADKYAGVEETEA-LDDEDAP-RPFKAYLDVGLKRTSTGSRVFGALKGASDGGIYIPHNEKRLPGYDVESKELDAEVLKKYIYGGHVAEYMESLEEEDDERFKKQFSTYLADGVGSEDIEEIYTNAYAAIRED--PTFKPTEESKKYRRSTYAER Rhior3 ----------------------------------------MVVRFTNKDIICQIIYAKLQGDFVLSAAYAHELPRYGIKGGLTNWAAAYATGLLLARRTLTKLGLADKYEGFAEIEA-A--EGAP-RPFKAFLDVGLARTSTGARVFGAMKGASDGGIYIPHSGNRFPGFDIETKTNDDELLRNYIFGIHVAEYMEYLEEEDEERYKKQFATFIKQGITSDAVEDMYAEAHAAIREN--PLPQITE--TLHKRLTKKER Rhoto1 VKEQKNQVKYRRRREGKTDYYARKRLVVQAKNKYASPKYRLVVRITNKDVICQIVSAKLQGDVVLAAAYSHELPRYGIKHGLTNWAACYATGLLCARRALTKLGLADKYEGVTETEP-I--EGEP-RPFKCFLDVGVARTSTGARVFGAMKGASDGGVFIPHSEQRFPGFDPESKELDAETLQRYIYGGHVAEFMETLEEEDDERFKKHFSTYLEDDISSEDIEDMYREAHEKIRED--PTYTKTDASKKTHKLSTAER Rozal11 VKEIKNQTKYRRRREGKTDYYARKRLIIQDKNKYNSPKYRMVVRFTNKDIICQMVYARIQGDVVIASAYAHELPRYGVQVGLTNYAAAYCVGLLLARRVLTKFNLASKYEGQTEVEA-I--EDGP-RPFKAYLDVGLRRTSTGARVFGAMKGAADGGIFIPHSEKRFPGYDSSSKTLDAETLRNYIYGGHVSEYMEYLQEEDEERYKIQFSKYIELGIEADAVEEMYQNAHEAIRAD--PSYQPTEKKDMYRKMNLAQR Sacce1 QKDAKSQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVEETEA-V--EDGP-RPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSAHEAIRAD--PAFKPTEESKKYRKLSKEER Salro LKVVKNQVKYRRRRTGQTDYFARRKLIQQDKNKYNTPKFRLVVRRTNRDVIAQVAYSRLEGDYVVAAAYSHELKQFGIKVGLTNYAACYATGLLLARRLLTKYNLADRYTGVEEVEKGV--QSGP-RPFRAFLDVGLAPTTTGARVFAVMKGAVDGGLAVPHNHKRFPGYDEEAKAFDAEVLRDYIFGEHVANYMRELQEEDADKYNRLFSEYVKQGVSADDLEQMYADAHKAIRED--PNRKKKPERKNYGRMSLAQR Schco3 VKKVKTQVKYRRRREGKTDYYARKRLVTQAKNKYNAPKYRLVVRFTNKQVIVQIVYARLQGDFVLAAATSKELPRYGINHGLTNWTAAYATGLLVARRALTKLGLADKYEGVTETEA-LDEEDAP-RPFKAYLDVGLKRTSTGSRVFGAMKGASDGGIFIPHSDKRFPGYDPESKELDDEVLKKYIYGGHVAEYMESLEEEDDERFKKQFSTYLEDGVGSEDIEEIYTNAYAAIRED--PTFKPTEETLKYKRLTYEQR Schpo1 IKAVKSQTKYRRRREGKTDYYARKRLIAQAKNKYNAPKYRLVVRFSNRFVTCQIVSSRVNGDYVLAHAHSSELPRYGIKWGLANWTAAYATGLLVARRALAKVGLADKYEGVTETEA-I--EDGP-RPFKVFLDVGLKRTSTGSRVFGAMKGASDGGLFIPHSPNRFPGFDIETEELDDETLRKYIYGGHVAEYMEMLIDDDEERYQKQFSGLIADGIESDQLEDIYAEAYAKIRED--PSFQKSGESLKYTKLTAEER Sorma HKLVKNQTKYKRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNRDIILQVVSSEITGDKVFASAYSHELKAYGIENGLTNWAAAYATGLLLARRVLKKLGLDETFKGVEETEA-AETDDGERRPFKCFLDVGLARTSTGARVFGAMKGASDGGICIPHSENRFPGFDMESEELDAETLKKYIFGGHVAEYMETLADDDEERYKSQFNRYIENDVEADGLEDLYAEAHAAIRED--P-FKKAEESLKYRKLTREQR Sphar VKVVKNQVKYRRRREGKTDYYARRKLVRQDKNKYNTPKYRLCVRFTNKDVICQVAYATIEGDRIICAAYSHELPRYGVKVGLTNWAACYATGLLLARRLLTKYNLADKYEGNTNVEE---NVEGP-RPFRCFLDVGLARTSTGAKIFGAMKGAVDGGLDIPHNEKRFPAWSKDTPEEYVEFLKRYVYGGHVADFMEELEEEDEDKYKVQFARYIAEDISFDDLEDMYKECHEAIRAD--PSPKEKSEGQKHKKLTYAQR Spipu1 VKLVKNQTKYRRRREGKTDYYARKRLVTQAKNKYNSPKYRLVVRITNKDIITQIVYAKLQGDVVLAAAYAHELPRYGIKHGLTNWAAAYATGLLLARRVLAKLGLDSKYEGQTEVEP-L--DDGP-RPFTAYLDTGLRRTTTGHRIFGALKGAADGGLRVPHSESRFPGW--DGKEIDAELLRGYIFGRHVADYMEYLQEEDEEAYKRQFASYIEDEVEPDDLEDLYTEAHKAIREN--PLAEKKEKLKRFKRLGLKQR Sporo1 ------QVKYRRRREGKTDYYARKRLVVQAKNKYASPKYRLVVRITNKDVVCQIVSAKLQGDVVLTAAYAHELPRYGIKHGLTNWSACYATGLLCARRALTKLGLADKYEGFTEVEA-I--EGDV-RPFKCFLDVGLARTSTGARIFGAMKGASDGGIFIPHSEGRFPGFDPESKELDAETLQRYIYGGHVAEFMESLEEEDEERFRKHFSRYLADDISSEDIEDMYREAHEKIRED--PTYQKTEASRKTHKLSLQQR Stehi1 VKKVKSQVKYRRRREGKTDYYARKRLVSQAKNKYNAPKYRLVVRFTNREVICQIVYARLQGDFVLAAARSKELPRYGINHGLTNWTAAYATGLLVARRALNQIGLADKYEGVAEIEA-LDDEDAP-RPFKCYLDVGLKRTSTGSRVFGALKGASDGGIFIPHNEKRFPGFDPESKELDAETLKKYIFGGHVAEYMESLEEEDDERFKKQFSTYLADGVGSEDIEEIFQNAYAAIRED--PAFKPTEESLKFKRLTYAQR Tapde11 QKTVKNQTKYRRRREGKTDYYARKRLISQAKNKYNAPKYRLVVRFAKKDITCQIVYSKIEGDVVFAAAYAHELPKYGIKHGLTNWSAAYATGLLVARRALKKLGLDETYTGVEETEA-V--DDAP-RPFKVFLDVGLKRTSTGSRIFGALKGASDGGLFIPHSPNRFPGWDIEGEELDAETLRKYIFGGHIAEYMEMLQDDDEERFSKQFAGLIEDGIESDQLEDIYAEAHKKIRED--PTFVPSEESQKYQKLTLEER Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 VKVQKSQVKPRRRREGKTDYYARRRLVTQAKNRYESHKYRLVVRITNRQVICQVVYAKLQGDFVLCHASSKELPRYGIEHGLTNWTAAYATGLLCARRALTKLGLADKYEGVTETEP-LGD-DEP-RPFKCYLDVGLRRTSTGSRIFGAMKGASDGGIFIPHSDRRFPGFDPETKTLDAEVLQKYIVGGHVAEYMESLEEEDDERFKKQFATYLASDISSADIEEMYTSAYAAIRED--PSFKPTEESRKLRKLNREQR Trire2 QKLAKNQTKYKRRREGKTDYYARKRLITQAKNKYNAPKYRLVVRFTNKDIIMQIVSSEISGDKVLVAAYSHELRAYGINHGLTNWSAAYATGLLIARRVLSKLGLDKDFVGVEETEA-AETENGERRPFKAFLDVGLARTSTGARVFGALKGASDGGILVPHSEKRFPGYDIESKELDAETLRKYIYGGHVAEYMETLADDDEERYTSQFAKYIEDDVEADGLEDLYTEAHKAIRED--P-FKKVEISKKYKRLSKAEK Umbra1 VKEQKNQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNRDIICQVVYAKLQGDHVLTAAYAHELPRYGIKGGLTNWAAAYATGLLVARRTLAKLGLDEKYEGVTETEA-I--EDGP-RPFKAFLDVGLKRTSTGSRLFGAVKGASDGGIYIPHGENRFPGFDIESKSLDAELLRNYIYGIHVAEYMEYLQDEDEERYRKQFATFIAEGITSDEVEDMYTEAHAAIRED--PSAKPTEKVKAYKRLNKKQR Ustma22 VKTVKSQVKYRRRREGRTDYYARKRLVSQAKNKYNAPKYRLVVRFSNRYVTCQIVHAKIVGDFVLTQASSKELPRYGVKTGLSNWTAAYATGLLVARRALTLLGLADKYEGVTEVEP-LGD-DEP-RPFKCFLDVGLKRTSTGSRVFGALKGASDGGIFIPHSEKRFPGFDPEAKELDAELLRSYIYGGHVAEYMESLEEEDDERFKKQFSTALEQDIGSEDLEDMWTEAFEKIRED--PSFTPSDESKKYKKLTYEQR Walse1 VKEAKNQVKYRRRREGKTDFYARKRLVTQAKNKYNAPKYRLVVRFTNKDIICQIVSSKIQGDVVLTHARARELPKYGIKHGLTSWSAAYAVGLLVARRALTKLGLADKYEGDAETEP-LG-DDEP-RPFKVFLDVGLKRTSTGSRVFGALKGASDGGLYVPHSENRFPGYDIESKELDPEILQKYIVGGHIAEYMEELEEEDEERFKKQFSTYLEDGVGSDDIEEIYTSAHEKIREN--PEFQKSTISQGYKKLTKSQR Zygro1 FKNLKNQTPFRRRREGKTDYYQRRKLVTQHKAKYASPKYRLVVRFTNKDIICQIVSSQITGDIVLAAAYSHELPRYGITHGLTNWAAAYATGLLVARRVLQKLGLDKVYPGVEETEA-V--EDGP-RPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSPKRFPGFDFESEELDADLLRSYIFGGHVSQYMEELADDDEERYQELFRGYIADDIDAESVEEIYQQAHEAIRAD--PSFKPTEESKKYKKLSKEQK [Cluster1269.fasta_al_trimmed; alignment length = 101] Allma1 VNVPKTRNTFCCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMALKRCKHFELGGEKKQKGQALTY Ashgo11 VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKQIFRKKAKTTKKVVLRLECLSCKTKAQLPLKRCKHFELGGEKKQKGQALQF Aspfu1 VNVPKTRRTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECTACKTKKQLALKRCKHFELGGDKKTKGAALVF Aurde31 VNIPKTRRTFCCRKHTPHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQLALKRCKHFELGGEKKTKGAALQF Batde5 VNIPKTRNTFCCRKHTPHKVTQYKTGKASLFAQGKRRYDAKQSGYGGQTKPVFHKKAKTTKKVVLRLECSVCKHKQQVSLKRCKHFELGGDKKTKGAALSF Botbo1 VNIPKTRRTYCCKKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECTVCKYKMQLALKRCKHFELGGEKKTKGAALQF Botci1 VNVPKTRRTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTSCKTKAQLALKRCKHFELGGDKKTKGAALVF Caeel VNVPKARRTFCCRKHTNHKVTQYKKGKESKFAQGRRRYDRKQSGFGGQTKPIFRKKAKTTKKIVLRMECTECKHKKQLPIKRCKHFELGGQKKSRGQVIQF Canalb1 VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKQIFHKKAKTTKKVVLRLECVVCKTKAQLPLKRCKHFELGGDKKQKGQALQF Cangl VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVNCKTKAQLTLKRCKHFELGGEKKQKGQALQF Capow VNVPKTRKTFCCKKHTLHKVSQYKTGKASVFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECSVCKYKKQLALKRCKHFELGGDKKRKGQALIF Catan2 VNIPKTRNTFCCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECTSCKYKMQISLKRCKHFELGGEKKQKGQALQY Cioin VNVPKTRKTYCCKKHTLHKVTQYKTGKASLYAQGKRRYDRKQSGYGGQTKVVFRKKAKVTKKIVLRMECSQCKARKQLAIKRCKHFELGGDRKRKGQMIQF CocheC53 VNVPKTRRTYCCKKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKRAKTTKKVVLRLECTACKTKAQLALKRCKHFELGGDKKTKGAALVF Coere1 VNIPKTRNTFCCRKHTPHKVTQYKAGKASVFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECTVCKFKQQLALKRCKHFELGGDKKRKNAALVF Conco1 VNIPKTRNTFCCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGFGGQTKPVFKKKAKTTKKVVLRLECSVCKYKQQLPLKRCKHFELGGDKKTKGAALVF Conpu1 VNIPKTRRTYCCKKHTPHKVTQYKKGKDSIFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQLSLKRCKHFELGGEKKTKGAALQF Copci VNIPKTRRTYCCKKHTPHKVTQYKKGKDSIFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQVSLKRCKHFELGGEKKTKGAALTF Croqu1 VNIPKTRRTFCCKKHTPHKVTQYKTGKASLSAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQVALKRCKHFELGGDKKTKGAALVF CryneH991 VNIPKTRRTYCCRKHTPHKVTQYKKGKDSLSAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKTKHQLALKRCKHFELGGDKKQRGAAISF Crypa2 VNIPKTRKTYCCKKHTLHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECSQCKTKLQLALKRCKHFELGGDKKTKGAALVF Debha1 VNVPKTRRTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQKGYGGQTKPVFHKKAKTTKKVVLRLECVVCKTKAQLSLKRCKHFELGGDKKQKGQALQF Dekbr2 ----------------------------------------------------------------------------------------------------- Dicdi VNIPKARKTHCCNKHTPHKVTQYKAGKPSLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKIVLRMECS-CGYKKQQVLKRCKRFELGGEKKSKNEAIKI Dmel VNVPKQRRTFCCKVHKLHKVTQYKKSKERKGAQGRRRYDRKQQGFGGQTKPIFRKKAKTTKKIVLRMECTECKYRKQTPLKRCKHFELGGDKKRKGQMIQF Enthi VVVPKTRKTYCCDKHTPHKVSQYKKGKDSLHVQGKRRYDRKQQGFGGQTKPVFKKKAKTTKKVVLKIECTKCKYKLQKCLKRCKHFELGNEKKDK------ Falba VNFPKTRRSFCCRKHTQHRVTQYRAGKRRFFAQGERRYRAKQAGFGGQTKPIFHKKAKVTRKITLRLECSDCSHRFQFSLKRCKSFELGGATKSSSD---- Fomme1 VD--------CCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKAQLPLKRCKHFELGGDKKTKGAALTF Fusgr1 VNIPKTRNTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECVKCKTKLQLALKRCKHFELGGDKKTKGAALVF Galma1 VNIPKTRRTYCCKKHTPHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMSLKRCKHFELGGEKKTKGAALTF Ganpr1 VNVPKTRNTYCCRKHTAHKVSQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECNSCKYKHQLAIKRCKHFELGGEKKTKGAALSF Gloin1 VNVPKTRNTYCCKRHRPHKVSQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECQSCKFKHQIALKRCKHFELGGDKKTKGAALVF Hisca1 VNVPKTRRTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFRKKAKTTKKVVLRLECTVCKTKAQLALKRCKHFELGGDKKTKGAALVF Klula1 VNVPKTRKTYCCRKHAQHKVTQYKAGKASLYAQGKRRYDRKQSGFGGQTKQIFHKKAKTTKKVVLRLECMSCKTKTQLALKRCKHFELGGEKKQKGQALQF Lacbi2 VNIPKTRRTYCCKKHTPHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECNVCKYKMQLTLKRCKHFELGGEKKTKGAALTF Lenti61 VNIPKTRRTYCCRKHTPHKVTQYKKGKDSLAAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQLSLKRCKHFELGGEKKTKGAALQF Malgl1 RTSPTDTLT------SPHKVTQYKAGKASEFAQGKRRYVRKQKGYGGQTKPVFQKKAKTTKKVVLRLECTVCKYRSHLALKRCKHFELGGEKKTKGAALVF Mellp23 VNIPKTRRTYCCKKHTPHKVTQYKTGKASLSAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQLALKRCKHFELGGDKKTKGAALVF Mnele ----------------------------------------------------------------------------------------------------- Monbr VNVPKNRKTFCCRKHTLHKITQYKAGKASLYAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRMECIECKYKSQKALKRCKHFELGGDKKRKGAMINF Morel2 VNVPKTRNTYCCKKHTAHKVSQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECQVCKYKHQIALKRCKHFELGGDKKQKGQALTF Mucci2 VNIPKTRNTYCCRKHTPHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECTACKYKMQLAIKRCKHFELGGDKKTKGAALVF Mydma VNIPKTRKTFCCRKHTLHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRMECTDCKYRKQIPLKRCKHFELGGDKKRKGQMIQF Neucr2 VNVPKTRKTYCCGKHTLHKVTQYKAGKASAFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECSVCKQKKQLPLKRCKHFELGGDKKTKGAALVF Orpsp11 VNIPKTRKTFCCRKHTLHKVTQYKTGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKIVLRLECTVCKYKQQLAIKRCKHFELGGEKKV------- Pench1 VNIPKTRRTYCCHKHQQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTACKAKKQLALKRCKHFELGGDKKTKGAALVF Phybl2 VNIPKTRNTFCCKKHTPHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLECTACKYKMQLSIKRCKHFELGGDKKTKGAALVF Picst3 VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKQIFHKKAKTTKKVVLKLECVVCKAKSQLPLKRCKHFELGGDKKQKGQALQF Plicr1 VNVPKTRRTYCCKKHTPHKVTQYKKGKDSLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMSLKRCKHFELGGEKKTKGAALTF Polpo VNIPKARKTLCCNKHTPHKVTQYKAGKPSLFAQGKRRYDRKQRGFGGQTKPVFHKKAKTTKKIVLRMECS-CGAKKQQVIKRCKRFELGGEKKKKGEAMKI Pucgr2 VNIPKTRRTYCCKKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRMECTVCKYKKQVALKRCKHFELGGDKKTKGAALVF Punst1 VNIPKTRRTYCCKKHTPHKVTQYKKGKDSLAAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQLSLKRCKHFELGGEKKTKGAALTF Rhior3 VNIPKTRNTFCCRKHTPHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTACKYKMQIALKRCKHFELGGDKKTKGAALVF Rhoto1 VNVPKTRRTYCCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMALKRTKHFELGGDKKQKGQALVF Rozal11 VNVPKSRNTFCCRKHTLHKVTQYKTGKASLFAQGKRRYDRKQAGYGGQTKPVFHKKAKTTKKVVLRLECTSCKHKHQIALKRCKHFELGGEKKVKFSYLTL Sacce1 VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECVKCKTRAQLTLKRCKHFELGGEKKQKGQALQF Salro VNVPKSRRTFCCSKHRLHKVTQYKAGKASLFAQGKRRYDRKQSGFGGQTKPIFRKKAKTTKKIVLRLECTVCKNRQQQVIKRCKVFILGGDKKRKNAMITF Schco3 VNIPKTRRTYCCKKHTPHKVTQYKKGKDSIFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTSCKYKMQLPLKRCKHFELGGEKKTKGAALQF Schpo1 VNIPKTRKTYCCRKHTVHRVTQYKKGPDSKLAQGKRRYDRKQSGFGGQTKPVFHKKAKVTKKVVLRLECVSCKYKNQLVLKRCKHFELGGEKKTKGAAIQF Sorma VNVPKTRKTYCCGKHTLHKVTQYKAGKASAFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECSVCKQKKQLPLKRCKHFELGGDKKTKGAALVF Sphar VNIPKSRKTFCCKRHRLHKVTQYKAGKASLYAQGKRRYDRKQSGFGGQTKPVFRKKAKTTKKICLRLECTHCRAKKQLVIKRCKHFELGGDKKRKGMAIAF Spipu1 VNIPKTRNTYCCKKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECTVCKYKQQIALKRCKHFELGGDKKTKGAALQF Sporo1 VNVPKTRRTYCCRKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTACKYKMQLSLKRCKHFELGGDKKQKGQALQF Stehi1 VNIPKTRRTYCCKKHTAHKVTQYKKGKDSLAAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECVDCKYKMQMSLKRCKHFELGGEKKTKGAALTF Tapde11 VNIPKTRKTYCCRKHTQHKVTQYKKGRDSLFAQGKRRYDRKQKGYGGQTKPVFHKKAKTTKKVVLRLECVSCKYKMQISLKRCKHFELGGDKKTKGAALTF Thetr VNVPKTRNTYCCKKHQLHKVTQYKTGKASIFAQGKRRYDRKQKGFGGQTKPIFHKNAKTTKKITLRLECTKCKARHMKVLKRCKKFELGGEKKVKGAALQF Treme1 -----TRRTYCCKKHTPHKVTQYKKGKDSLAAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTSCKTKHQLTLKRCKHFELGGDKKQRGAALNF Trire2 VNIPKTRNTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECVKCKTKLQLALKRCKHFELGGDKKTKGAALVF Umbra1 VNIPKTRNTYCCKKHTPHKVTQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMALKRCKHFELGGDKKTKGAALVF Ustma22 VNVPKTRRTYCCKKHTPHKITQYKTGKASLYAQGKRRYDRKQKGYGGQTKPVFHKKAKTTKKVVLRLECTQCKYRSHVALKRCKHFELGGDKKQKNAALVF Walse1 VNIPKTRRTYCCRKHTPHKVTQYKKGKDSIYAQGKRRYDRKQSGFGGQTKPVFHKKAKTTKKVVLRLECSVCKYKMQLSLKRCKNFELGGEKKQKGAALNF Zygro1 VNVPKTRKTYCCRKHTQHKVTQYKAGKASLFAQGKRRYDRKQRGFGGQTKPIFRRKAKTTKKVVLRLECVQCKTRAQLSLKRCKHFELGGEKKQKGQALQF [Cluster1284.fasta_al_trimmed; alignment length = 114] Allma1 KRTFRKFSYRGVELDQLMDLTSDRARRRFQRGL--KRKLIKKLRKAKEKPATVKTHLRNMIIVPEMIGSVVGVYNGKTFNQVEIKPEMVGHYLGEFSITYKPVKHGRPGSSRFV Ashgo11 KRTFKTYSYKGVDLEKMLEMPTERVRRRFARGL--SSKLMKKLRAAKEKPAVVRTHLRNMIIVPEMIGSVVGVYNGKVFNQVEIKPEMVGHYLGEFSITYTPVRHGRAGTSRFI Aspfu1 RRQFRKFTYRGIDLDQLLDLSSERARRRFNRGL--KRKLIKKLRKAKEKPELVKTHLRDMIIVPEMIGSVIGIYSGKEFNQIEVKPEMVGHYLGEFSITYKPVKHGRPGSSRFI Aurde31 KRTFRTFSYRGIELDKLLDLSNERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLAEFSISYKPVKHGRPGSSRFI Batde5 KRSFRKFSYRGVDLEQLLDLSSERARRRFQRGL--KRKLIKKLRKAKEKPAAVKTHLRNMIVVPEMIGSIVGIYNGKTFNQVELKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Botbo1 KRTFRTFSYRGIELDKLLDLSNERARRRFGRGI--KGRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKTFNAVEIKPEMTGHYLAEFSISYKPVKHGRPGSSRFI Botci1 KRAFRKFSYRGIDLDQLLDLSSDRARRRFNRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYRPVKHGRPGSSRFI Caeel KRTFRKFMYRGVDLDQLLDMSRERMRRRLDRGL--KRKLIAKVQKAKEKPATVKTHLRDMIILPELVGGVIGIYNGKVFNQTEIKPEMIGFYLGEFAISYKPVKHGRPGSSRFI Canalb1 KRTFKQFSFKGVDLKDLVEMPTERVRRRFSRGL--DSKLIKKLRAARERPAVVKTHLRNMIVVPEMIGSVVGVYNGKVFNTVEIKPEMVGHYLGEFSITYTPVRHGRAGSSKFM Cangl KRVFKTHSYRGVDLEKLLEMSTERVRRKFSRGV--SGKFMKKLRAAKEKPAVVKTHLRNMIIVPEMIGSVVGIYNGKVFNQVEIRPEMLGHYLGEFSITYTPVRHGRAGTSRFI Capow KRTFRKYSYRGVDLDQLLELSSERARRRFHRGL--KRKLLKRLRKAKEKPATIKTHLRDMIIVPEMIGSVVGIYNGKVYNQVEIKPEMTGHYLAEFSISYKPVRHGRAGSSRFI Catan2 KRTFRKFTYRGVDLEDLMDLTSERARRRFQRGL--KRKLIKKLRKAREKPAVVKTHLRNMIIVPEMIGSIVGVYNGKTFNQVEVRPEMVGHYLGEFSITYKPVKHGRPGSSRFV Cioin KRTFRKYTYRGVDLDRLLDMSRERQRRSFNRGV--KRKLLKRLRKAKEKPEVIKTHLRNMVIEPEMVGSMVGVYNGKVFNQVEIKPEMIGRYLGEFSITYKPVKHGRPGSSRFI CocheC53 KRAFRKFSYRGVDLDQLLDLGSERARRRFNRGL--KRKLIKKLRKSKEKPDLVKTHLRDMIVVPEMIGSVIGVYSGKEFNQVEIKPEMVGHYLAEFSISYRPVKHGRPGSSRFI Coere1 RRTFRKFSYRGVDLEQLLDVSSERVRRKFKRGL--KRKLIKKLRLAKEKPECVKTHLRNMIIVPEMIGSIIGIYNGKTFNQVEIKPDMIGHYLGEFSITYKPVKHGRPGSSRFI Conco1 KRIFKKFFFRGIELDNLLDLSSERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIVVPEMIGSVIGIYNGKTFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Conpu1 RRTFRTFSYRGVELDKLLDLSNERARRRFGRGL--KRRLIKKLRKAKEKPSVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLGEFSCSYKPVKHGRPGSSRFI Copci KRTFRTFSYRGIALDKLLDLSNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMVGHYLAEFSCTYRPVKHGRPGGWRDA Croqu1 RRAFRKFQYRGVELEALLDLSNERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMLIVPEMIGSVIGIYNGKTFNAVEIKGEMVGHYLGEFSISYKPVKHGRPGSSRFI CryneH991 SRSFKKYQYRGVELENLLDLSNERARRRFQRGL--KRRLIKKLRKAKEKPAMVKTHLRDMIIVPEMIGSVVGVYNGKTFTTVEVKPEMTGHYLGEFSITYKPVGHSRGADSRFV Crypa2 KRTFRKFSYRGIDLDQLLDLSSDRARRRINRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Debha1 KRVFKTFSYKGVDLKDLLEMPTERVRRRFSRGL--GSKLITKLRAAKEKPAIVKTHLRNMIVVPEMIGSVVGVYNGKVFNTVEVKPEMVGHYLGEFSITYAPVRHGRAGSTRFI Dekbr2 KRSFKSFSYKGVELEKLLSMSTERIRRKFSRGL--DSKLIKKMRKAKGKPVLVKTHLRNMIIVPEMIGSLVGIYNGKVFNTVEIKPEMVGHYLGEFSITYNPVQHGKAASK--- Dicdi KRTFKKFTYSGVALESLLDLKEERARRKLRRET--PIKFLKKCRASKEKPALVKTHARNILIVPEMIGSVIGIYNGKVFNQVEVKPEMIGHYTGEFSLSYKSVNHGRPGSSRFI Dmel KRTFKKFTYRGVDLDQLLDMPNNRARRRFSRGL--KRKLIKKLRKAKEKPEIVKTHLRNMIIVPEMTGSIIGVYNGKDFGQVEVKPEMIGHYLGEFALTYKPVKHGRPGSSRFI Enthi KRTFKKFEFQGKSLEEITTMPEPRMRRSYNRAP--KLKLVKKLLKIKEKPKLVKTHCRDKIILPNMIGSVIGVYNGKSFTTVEIKPEMIGHYLGEFSITYKPVTHGRPGSSKFV Falba RRTFRKFYFRGHETDTLLNLPQERVRRKFSRGI--GTKLMKRLTAAKERPAYIKTHLRNMIVVPEMIGSNVAIYNGKTFNQVEIKPEMVGHYLGEFSLTYKPVFHGRPGASKFI Fomme1 RRTFRTFSYRGVELDKLLDMKNERARRRFQRGL--KKRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLAEFSCSYKPVKHGRPGCCSFL Fusgr1 KRAFRKFSYRGIDLDQLLDLSSDRARRRINRGL--KRRLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Galma1 KRIFRTFSYRGVELDKLLDMNNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLGEFSCSYRPVKHGRPGSSRFI Ganpr1 KRTFRKFTFRGVDLDQLLDLSSERVRRKFQRGL--KRKLIKKLRKAKEKPAVVKTHLRNMVIVPEMIGSQIGIHNGKTFNQVEIKPEMVGHYLGEFSISYKPVKHGRPGSSRFS Gloin1 KRTFKKYSYRGVDLEQLLDLNSERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSIVGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGSSRFI Hisca1 KRAFRKFSYRGIDLNQLLDLSSERARRRFNRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSIIGIYSGKEFNQVEIKPEMVGHYLGEFSISYKPVKHGRPGSSRFI Klula1 KRSFKTYSYKGVDLEKLLEMPTERVRRKFARGL--SEKLMKKLRAAKEKPAVVRTHLRNMIIVPEMIGSVVGVYNGKVFNQVEIRPEMVGHYLGEFSITYTPVRHGRAGTSRFI Lacbi2 KRTFRTFSYRGVELDKLLDMSNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLAEFSCSYRPVKHGRPGSSRFI Lenti61 KRTFRTFSYRGVELDKLLDLSNERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMVGHYLAEFSCSYKPVKHGRPGSSRFI Malgl1 KRTFRKFSYRGVDLDDLLDMSNERARRRFSRGL--KRRLIKKLRKAKEKPAVVRTHMRDMIVVPEMIGSMIGVYNGKVCSHT----------------------------DLF- Mellp23 KRSFRKFQYRGIELEALLDLSNERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMLIVPEMIGSVIGIYNGKTFNSVEIKGEMVGHYLGEFSISYKPVKHGRPGSSRFI Mnele KRTFKKYTYRGIDLDKLLDMTSARARRRFTRGL--KRKLIKKLRKAKEKPEAVRTHLRNMIVTPEMVGSIVGIYNGKTFNQVEIKAEMIGHYLGEFSITYKPVKHGRPGSSRFI Monbr KRTFRKYSYRGIDLDKLLDLSEERVRRKFKRGL--KRQLLKKLRAAKEKPDVVKTHLRNMVIVPEMIGSMVGVYNGKTFNQVEIKAEMTGHYLGEFSITYKPVKHGRPGSSRFI Morel2 KRTFRKFSYRGIDLDKLLDLSSERPRRRFQRGL--KRKLIKKLRQAKEKPAVVKTHLRNMIVVPEMIGSVVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGSSRFI Mucci2 KRTFRKFTYRGIDLEQLLDLSSERARRRFQRGL--KRKLIKKLRAAKEKPEVVKTHLRNMIIVPEMIGSVIGIYNGKVFNQVEIKPEMTGHYLAEFSISYKPVKHGRPGSSKFV Mydma KRTFKKFTYRGVDLDQLLDLSNERARRRCDRGL--KSKLIKKLTNAKEKPAVVKTHMRDMLVLPSMIGSIIGVHNGKTFNQVEIKPEMIGHYLGEFSMTYKPVRHGRPGSSRFI Neucr2 KRTFRKFSYRGIDLDALLDLGSDRARRRINRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Orpsp11 RRTFRKYSYRGVELSRLLDLNTERKRRKFQRGL--KRKLIKKLRKAKEKPECVKTHLRNMVIVPEMIGSIVGIYNGKTFNQVEIKPDMIGHYLGEFSITYKPVKHGRPGSSRFV Pench1 RRQFRKFSYRGIDLDQLLDLSSERARRRFNRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVVGIYSGKEFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Phybl2 KRTFRKFTYRGIDLEQLLDLSSERARRRFQRGL--KRKLIKKLRNAKEKPATVKTHLRDMIIVPEMIGSVVGVYNGKTFNQVEIKPEMTAHYLAEFSISYKPVKHGRPGSSRFV Picst3 KRNFKTFSFKGVDLKDLVEMPTERVRRRFSRGL--DAKLIKKLRVAREKPAVVKTHLRNMIVVPEMIGSVVGVYNGKVFNTVEIRPEMVGHYLGEFSITYTPVRHGRAGSARFI Plicr1 KRTFRTFSYRGVELEKLLDLKNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIVVPEMIGSVVGIYNGKVFNSVEIRPEMTGHYLAEFSCSYRPVKHGRPGSSRFI Polpo KRTFKKFSYGGVALESLLDLKEDRARRKV---L--SIK--------KDKPKLVKTHARNILIVPEMIGSMVGIYNGKVFNQVEIKPEMIGHYLGEFSLTYKTVNHGRPGSSRFI Pucgr2 ------------------------------------------------------------------------------------------------------------------ Punst1 KRTFRTFSYRGVELDKLLDLGNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMTGHYLAEFSCSYKPVRHGKPGSSRFI Rhior3 KRTFRKFTYRGVELDQLLDMSSERARRRFQRGL--KRKLIKKLRAAKERPDVVKTHLRDMIIVPEMIGSVVGIYNGKTFNQVEIKPEMTGHYLGEFSITYKPVKHGRPGSSKFV Rhoto1 ARTFKKFSYRGVELAQLLDLDSARARRRFQRGL--KRKLMKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMVGFYLGEFSITYKPVRHGRPGSSRFI Rozal11 KRTFRKYTYRGVELENLLDLSSERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIVVPEMIGSVIGIYNGKVFNQVEIKPEMVGHYLGEFSITYKPVKHGRPGSSKFV Sacce1 KRVFKTHSYRGVDLEKLLEMSTERVRRRFARGM--TSKFMKKLRAAKEKPAPVRTHMRNMIIVPEMIGSVVGIYNGKAFNQVEIRPEMLGHYLGEFSITYTPVRHGRAGTSRFI Salro KRAFRKFTFRGIEVEQLLDLSHDRARRKLKRGL--KRKLLKKLRKVKEKPAPVKTHLRNMIILPEMIGSIVGVYNGKTFNQVEIRTDMVGHYLGEFSISYKPVRHGRPGSSRFI Schco3 KRTFRTFSYRGVELDKLLDLSNERARRRFQRGL--KRRLIKKLRKAKEKPAVVKTHLRDMIVVPEMIGSVIGIYNGKVFNSVEIKPEMVGHYLAEFSISYRPVKHGRPGSSRFI Schpo1 KRTFRTFAYRGVELEQLLDLSAERARRRMLRGL--GPNFIRKLRKAKEKPATVKTHLRNMIILPEMVGSVVGIYNGKLFNQVEIRPEMIGHYLGEFSITYKPTKHGRPGSSRFI Sorma KRTFRKFSYRGIDLDALLDLGSDRARRRINRGL--KRKLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFI Sphar KRTFRKFMYRGVDLDQLMDMSTQRIRRRLKRGI--NRKLIKRLRKAKERPHGIKTQLRNMVIVPEMIGSVVGIYNGKSFNGVEIKPEMIGTYLGEFSISYKPVAHGRPGSSRFI Spipu1 KRTFRKFTFRGVDLDQLLDLSSERARRRFQRGL--KRKLIKKLRKAKEKPEVVKTHLRDMIIVPEMIGSVVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGSSRFI Sporo1 ARTFRKFSYRGVELSQLLDLDSARARRRFQRGL--KRKLMKKLRKAKEKPEVVKTHLRDMIIVPEMIGSVVGIYNGKVFNQVEIKPEMVGFYLGEFSITYKPVRHGRPGSSRFI Stehi1 RRTFRTFSYRGIELDKLLDLSNERARRRFQRGL--KRKLIKKLRKAKEKPAVVKTHLRDMIIVPEMIGSVVGIYNGKVFNSVEIKPEMVGHYLGEFSVSYRPVKHGRPGSSRFI Tapde11 ARSFRRFQYRGIDLEPLLDLSSERARRKFQRGL--KRKLIKKLRQAKEKPAPVKTHLRDMIVVPEMIGSIVGIYNGKVFNQVEIRPEMVGHYLAEFSISYKPVKHGRPGSSRFI Thetr RRVFRKFTYRGVDLEQLLEMKQERQRRSINRGLLKKRSLLKKLRKAKEKPEPVKTHLRNMVIIPEMIGSVVGVYNGSQFNQVEIKPEMVGHFLGEFSITYRPVRHGRPGTARFI Treme1 PRTFKVYSYRGVTLDKLLDLDNERARRRFSRGL--KRRLIKKLRKAKEKPATVKTHLRDMIIVPEMIGSVVGVYNGKSFTTVEIKPEMTGHYLGEFSITYKPVGHSYGGDARFV Trire2 RRTFRKFSYRGIDLDNLLDLSSDRARRRINRGL--KRRLIKKLRKAKEKPDLVKTHLRDMIVVPEMIGSVIGIYSGKEFNQVEIKPEMVGHYLGEFSISYKPVKHGRPGSSRFI Umbra1 RRTFRKFSYRGVDLDQLLDLSSERARRRFQRGL--KRKLIKKLRAAKEKPTTVKTHLRDMIIVPEMIGSVVAIYNGKVFNQVEIKPEMVGHYLAEFSISYKPVKHGRPGSSRFV Ustma22 KRTFRKFTYRGVELDALLDMSNGRARRRFQRGL--KRKLIKRLRKAKEKPATVKTHLRDMIVVPEMIGSMIGIYTGRFFVNTEIKPEMVGHYLGEFAMTYIPTRHGAKGVDRFL Walse1 RRTFRKFQYRGIELDQLLDLKNERARRRFQRGL--KRGLIKKLRKAKEKPAVVKTHLRDMLVVPEMIGSQVAIYNGKVFNTVEIKPEMTGHYLGEFSISYKPVRHGRPGSSRFV Zygro1 KRTFRTYSYRGVDLEQLLTMSNERIRRRFARGL--GHKFMKKLRAAKEKPDVVKTHMRNMIVFPEMIGSVVGVYNGKVFNQVEIRPEMVGHYLAEFSISYTPVRHGRAGTSRFM [Cluster1292.fasta_al_trimmed; alignment length = 130] Allma1 MSLVVSEFSFILRVLNTNLEGKDKIMYALTAIKGVGRRYANLVCKKAEVDLNKRAGQLELERIVTIIQNPLQFKIPKWFLNRQKDIRTGEREDLERLKKIRAHRGLRHHWGVRVRGQHTKTTGRRGRTVG Ashgo11 MSLVVAEFQHILRLLNTNVDGNIKIVYALTTIRGVGRRYANLICKKADVDLNKRAGELELERVVQIMQNPTHYKIPAWFLNRQKDVNDGKRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRR-RG-- Aspfu1 -------------------------MYALTQIKGVGRRYSNLVCKKADVDLSKRAGELELERIVTILQNPTQYKIPTWFLNRQRDIVDGKREDLERLKKIRSHRGLRHYWGLRVRGQHTKTTGRRGRTVG Aurde31 MSLVAPDFQHILRLLNTNVDGKRKVMYALTEIKGVGRRYANIVCKKADVDLNKRAGDLELERIVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Batde5 ISLVVPNFQYIIRLLNTNIDGKRKIMYALTSIKGIGRRYANLVLKKADIDLNKRAGEVELERVVTIMQNPRQYKIPDWFLNRQKDIKDGKREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRTVG Botbo1 MSLVVPEFQHILRLLNTNVDGKRKIMFALTEIRGVGRRYANVVCKKADVDLKKRAGELELERIVTIMQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGIRVRGQHTKTTGRRGKTVG Botci1 MSLVTGEFQYILRLLNTNVEGKQKVMFALTKIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQYKIPSWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHSKTTGRRGRTVG Caeel MSLIIPEFQHIHRVMNTNIDGNRKVPYALTAIKGVGRRFAFVCCRKADVDVNKRAGELDFDKIVTIMQNPSQYKIPNWFLNRQKDIKDGKREDLERMKKIRLHRGLRHYWGLRVRGQHTKTTGRKGRTVG Canalb1 MPLVVQEFQHILRLLNTNIDGRIKIMYALTKIRGVGRRYANLVCKKADVELTKRAGELELERIVTIMQNPTNYKIPAWFLNRQKDQVDGKRDDLERLKKIRSHRGIRHFWGLKVRGQHTKTTSRG-R--- Cangl SSLVVAEFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYANLVCKKADVDLNKRAGELELERVVQIMQNPTQYKIPAWFLNRQRDIADGKRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRR-RA-- Capow MSLVLPEFTHILRMLNTNIDGKVKIPFALTKIKGVGRRYSNLVCKKADIDLKKRAGEVEVERLLSILQNPRSYKIPDWFLNRQKDIVDGKREDIERLKKIRAHRGLRHYWGVRVRGQHTKTTGRHGRTVG Catan2 -------------------------MYALTAIKGVGRRYANLVCKKAEVDTNKRAGDIELERIVTIIQNPLQFKIPKFFLNRQKDIRTGEREDLERLKKIRVHRGLRHWWG----SVSAVSTPRRVRPLV Cioin ---------------------------------------------------------------------------------------------------------------------------------- CocheC53 MSLVSGEFQYIIRLLNTNVDGKQKVMYALTKITGVGRRYSNLVCKKADVDLTKRAGDLELERIVTIIQNPLQYKIPSWFLNRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHSKTTGRRGRTVG Coere1 MSLVVTQFQAMRRVLNTNVHGNVKAMYALTAIKGVGRRYSNLVLKKADVDMTKRAGELELERIVDIIQNPLQYKIPKWYLNRQKDRTTGKREDLERMKKIRLHRGLRHFWGIRVRGQHTKTTGRGGRTVG Conco1 LSLVVSDFTHILRLLNTNVEGKQKIMYALTAIKGVGRRYSNLVCKKADVDLNKRAGECELERIVNIIQNPLQFNIPKYFLNRQKDIVDGTREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Conpu1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQYKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Copci MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYANLVCKKADVDLNKRAGELELERIVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Croqu1 QSLVVPEFQHILRLLNTNVDGRIKIMFALTQIRGVGRRLANVACKKADVDLNKRAGELELERIVTIIQNPAQFKIPNWFLNRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG CryneH991 MSFAPLEFQHILRLLNTNVKGGGKIMYALTEIKGVGRRYANLVCKKADVDLNKRAGELELERIVTIMQNPAQFKIPSWFLNRQRDINDGKREDLERLKKIRTHRGLRHHWGLKVRGQHTKTTGRRGRAVA Crypa2 MSLVSGEFQFILRLLNTNVDGKQKVVYALTKIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQYKIPTWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Debha1 -----MKFQTDLSLLNTNIDGRIKIMYALTKIRGVGRRYSNLVCKKADVDLKKRAGELELERIVTIMQNPTNYKIPAWFLNRQKDQVDGKRDDLERLKKIRAHRGIRHFWGLKVRGQHTKTTSRG-R--- Dekbr2 --------------MNTNVDGKIKIVYALTTIRGVGRRYANLICKKADVDLNKRAGELELERVVQIMQDPTKYKVPAWFLNRQKDLDDGKRDDIEKLKKMRAHRGLRHSWNLRVRGQHTKTTGRK-GKVS Dicdi SSLVFQGFQHIIRIYNTNVDGRRKIQYALTCVKGVGRRFANLVCKKADIDTSKRAGELEVERLTTIMNHPRQYNIPTWFLNRQKDIKDGKREDLERLKKIRAHRGVRHHFGLRVRGQKTKTTGRRGRTVG Dmel MSLVIPEFQHILRIMNTNIDGKRKVGIAMTAIKGVGRRYSNIVLKKADVDLTKRAGECEVDKVVTIISNPLQYKVPNWFLNRQKDIIDGKRDDLERLKKIRSHRGLRHYWGLRVRGQHTKTTGRRGRTVG Enthi MATVTSEFQHMLRVCNTNLDGRRKVPYALTGIKGCGRRYAYLVCKRAGIDVNKRAGLMEIEKIVDILNNPLNYKIPVWFLNRQKDNKDGKREDIEALKKMRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Falba MSAVAPEFTHILRLLNTNVEGKRKVVYALCSIQGVGRRFATLVVKKAGVCPEKRAGELEQDRLIDVIQNPVQYKIPNWFLNRRYDVVDGTREDLDRLKRIYSHRGIRHYLGLKVRGQHTKTTSRRGRVMG Fomme1 MSLVLPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNIVCKKADVDLSKRAGDLELERIVTIIQNPTQYKIPVWFLNRQKDINDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Fusgr1 MSLVSGEFQFILRLLNTNVDGKQKVMYALTKIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTILQNPTQYKIPTWFINRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Galma1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNLVCKKADVDLNKRAGDLELERLVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Ganpr1 MSLVITDFQHILRLLNTNIDGRRKIMYALTHIKGVGRRYSNMICKKADVDLTKRAGELELERIVTIIQNPRQYRVPDWFLNRQKDIKDGKREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRKGRTVG Gloin1 MSLVVPDFQHILRLLNTNVEGKTKVMFALTAIKGVGRRYSNLVCKKADIDLRKRAGELELERIVTIIQNPTQFKIPNWFLNRQKDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Hisca1 MSLVTGEFQFILRLLNTNVDGKQKIMYALTKIKGVGRRYSNLVCKKADVDLNKRAGEIELERIVTIIQNPTQYKIPTWFLNRQRDITDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Klula1 MSLVVQEFQHILRLLNTNVDGNINVVYALTTIRGVGRRYANLVCKKADVDLHKRAGELELERIVQIMQNPTHYKIPAWFLNRQKDVNDGKRDDLERLKKIRSHRGIRHFWGLRVRGQHTKTTGRR-RA-- Lacbi2 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Lenti61 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYANLVCKKADVDLNKRAGELELERIVTIIQNPTQFKIPTWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Malgl1 MSLAPPDFAHILRLLNTNVDGKRKIQYALTEIKGVGRRYANIVCKKADIDLTKRAGELELERIVNILQSPQEFKIPTWFLNRQKDFTTGKRDDLERLKKIRAHRGLRHYWELRARGQHTRTTGRRGRTVA Mellp23 MSLVVPEFQHILRLLNTNVDGRIKIMFALTQIRGVGRRLANVACKKADVDLNKRAGELELERIVTIIQNPAQFKIPNWFLNRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Mnele MSILIAAFQHILRVLNTNIDGKEKIMYALTAIKGVGRRYSNIVLKKADIDQTKRAGEIELERIMEIMQNPRDYKIPDYFLNRKKDIKDGKREDLERLKKIRSHRGLRHYWGLRVRGQHTKTTGRKGRTVG Monbr MSMVMPEFQHILRVMNTNIAGDRNIMYAMTAIKGVGRRYSNLCLKKAEISTRRRAGELDVRRVVTIMQNPRQYKIPDWFLNRKKDIKDGTRDDLERMKKIRLHRGIRHYWGVRVRGQHTKTTGRRGRTVG Morel2 ----------------------------MTNIKGVGRRYANLVCKKADIDLKKRAGELELERLVTIMQNPTQYKVPQWFLNRQKNFVDGKREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRVVG Mucci2 -SLVVPEFQHIIRLLNTNVDGRVKIQIALTSVKGVGRRFANIACKKADIDLTKRAGELELERIVTILQNPAQYKIPTWFLNRQKDIVDGKRDDLERLKKIRNHRGLRHYWGVRVRGQHTKTTGRRGRTVG Mydma MSLIVPEFQHILRVMNTNIDGKTKIMYAMTSIKGVGRRFSNICLKKADIDLKKRAGELEVERVITIMQNPRQYKIPDYFLNRQKDIKDGKREDLERLKKIKAHRGLRHYWGLRVRGQHTKTTGRKGRTVG Neucr2 MSLVSGEFNHILRLLNTNVDGKQKVVYSLTKIKGVGRRYSNLVCKKADVDLSKRAGELELERIVTIMQNPTAYKIPAWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Orpsp11 ----------------------QKLQFALTSIRGCGRRYANIVCKKAEIDLTKRAGELELERVVTILQNPTQYKIPNWFLNRQKDVVDGTREDLERLKKIRSHRGLRHYWGIKVRGQHTKTTGRRGRTVG Pench1 MSLVTGEFQFILRLLNTNVDGKQKIMYALTQIKGVGRRYSNLVCKKADVDLTKRAGELELERIVTILQTPTQYKIPSWFLNRQRDITDGKREDLERLKKIRSHRGLRHYWGLRVRGQHTKTTGRRGRTVG Phybl2 MSLVVPEFQHIIRLLNTNVDGKNKIVTALTSVRGVGRRFANIACKKADVDLNKRAGELELERIVTILQNPAQYKIPNWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Picst3 MPLVVQEFQHILRLLNTNIDGRIKIMYALTKIRGVGRRYANLVCKKADVDLTKRAGELELERIVTIMQNPTNYKVPAWFLNRQKDHVDGKRDDLERLKKIRSHRGIRHFWGLKVRGQHTKTTSRG-R--- Plicr1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Polpo MSLILPEFQHIIRIYNTNVDGRRKIMYALTNVKGIGRRFANLVCKKADVDLQKRAGELEVERLTTILNHPRQYNIPAWFLNRQKDIKDGKREDLERLKKIRAHRGIRHHMGLRVRGQKTKTTGRRGRTVG Pucgr2 MSLVVPEFQHILRLLNTNVDGRIKIMFALTQIRGVGRRLANVACKKADVDLNKRAGELELERIVTIIQNPAQFKIPAWFLNRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Punst1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYANIVCKKADVDLNKRAGELELERVVTIIQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGKTVG Rhior3 MSLVVPEFQHILRLLNTNVDGRVKIQIALTSVKGVGRRFANIACKKADIDLTKRAGELELERIVTILQNPAQYKIPNWFLNRQKDIVDGKREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRTVG Rhoto1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYANLVCKKADVDLGKRAGELELERIVTIMQNPLQFKIPQWFVNRQKDIVDGKREDLERLKKIRNHRGLRTYWGLRVRGQHTKTTGRRGKTVG Rozal11 MN-----FQHILRVLNTNIDGKNNVMYALTSIKGIGRRFANLACKKAEVNLKKRAGELELERLVTVVQNPQDYKIPEWFLNRQKDIKDGS--------KIRVHRGLRHFWGLRVRGQHTKTTGRRGRTVG Sacce1 MSLVVQEFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELELERIVQIMQNPTHYKIPAWFLNRQNDITDGKRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRR-RA-- Salro MSIVFPQFQHILRVLNTNLAGEENIMYSLTAIRGVGRRYSNLCLKKAEINQKQRAGQLDVDRIVKVMQNPLQYKIPKWFLNRQKDPKDGARDDFERMKKMRLHRGIRHMWGVRVRGQHTKTTGRRGKTVG Schco3 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNIVCKKADVDLNKRAGELELERIVTIMQNPTQFKIPTWFLNRQKDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Schpo1 MSLVVPDFQHILRLLNTNVDGKVKVMFAMTQIKGVGRRYANIVCKKADIDMSKRAGELELERIVTIIQNPSQFKIPSWFLNRQKDINDGKREDLERLKKIQTHRGLRHALDLRVRGQHTKTTGRRGKTVG Sorma MSLVSGEFNHILRLLNTNVDGKQKVVYSLTKIKGVGRRYSNLVCKKADVDLSKRAGELELERIVTIMQNPTAYKIPAWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Sphar GSLVIPEFHHILRLLNTNVDGKTKIVFALTSIRGLGRRYATLVCKKADVPLTKRAGELEIERIVTIMQNPRQYKIPDYFLNRQKDIKDGKREDIERMRKMRIHRGLRHWWGIRVRGQHTKTTGRRGRTVG Spipu1 ASITVPDFQHILRLLNTNIDGKRKVMYALTHIKGVGRRYANIVCKKADIDLSKRAGELELERIVVILQNPRQYKIPDWFLNRQKDIKDGKREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRTVG Sporo1 MSLVVPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYANIVCKKADVDLGKRAGELELERIVTIMQNPGQFKIPNWFVNRQKDIVDGKREDLERLKKIRNHRGLRTYWGLRVRGQHTKTTGRRGKTV- Stehi1 MSLVLPEFQHILRLLNTNVDGKRKIMYALTEIKGVGRRYSNLVCKKADVDLNKRAGELELERLVTIIQNPTQFKIPTWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHSWGLRVRGQHTKTTGRRGKTVG Tapde11 SSLVVPEFQHILRLLNTNVDGKNKIMFALTEIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIMQNPQQYKIPDWFLNRQRDIVDGKRDDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGKTVG Thetr MSCVEPDFQHILRVLNTNVDGKRKIVYALTAIKGVGRRFSTMVCKKADIDTTKRAGELEVEKVVDIITDPMKFNIPEYFFNRQRDFATGKREDLERLRKIRAHRGIRHLLGIPVRGQHTKTTGRHGRVVA Treme1 MSFAPPEFQHILRLLNTNVQGQGKIMFALTEIKGVGRRYANLVCKKADIDMSKRAGELELERIVTIMQNPAQFKIPSWFLNRQKDLADGKRDDLERLKKIRAHRGLRHHWHTRVRGQHTKTTGRRGKTMA Trire2 MSLVTGEFQFILRLLNTNVDGKQKVMYALTKIKGVGRRYSNLVCKKADVDLNKRAGELELERIVTIIQNPTQYKIPAWFLNRQRDIVDGKREDLERLKKIRAHRGLRHYWGLRVRGQHTKTTGRRGRTVG Umbra1 MSLAVPDFQHILRLLNTNVDGKNKIMVALTSIKGVGRRYANIACKKADVDLNKRAGELELERIVTILQNPSQYKIPNWFLNRQKDIVDGKREDLERLKKIRNHRGLRHYWGLRVRGQHTKTTGRRGRTVG Ustma22 MSLVPPDFAFILRLLNTNVDGKIKVQYALTQIKGVGRRYANIVCKKADIDLSKRAGELELERIVTILQNPAEFKIPSWFLNRQRDIVDGKRDDLERLKKIKAHRGIRHYLGLRVRGQHTKTTGRRGRTVA Walse1 ASLVAPEFQHILRLLNTNVDGKRKIQYAMTEIKGVGPRYANVVIKKADVDLFKRAGELELERIVSILQNPTQFKIPNWFLNRRKDITDGKRDDLERLKKIRAHRGLRHFWGIRVRGQHTKTTGRRGKTVG Zygro1 MSLVIQEFQHILRLLNTNVDGNIKVVYALTTIKGVGRRYANLVCKKADVDLSKRAGELELERIVQIMQNPTQYKIPTWFLSRQKDVNDGKRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRK-RA-- [Cluster1303.fasta_al_trimmed; alignment length = 136] Allma1 MKTEICSFSGYKIYPGHGKLFVRHDSKIFRFATSKAESYFHQRLNPRKIAWTTLYRRMHRKGI--TEEAAKKRTRRTVK-AQRAIVGASLELI-RAKRNQTAEVRAAARSEAAAKSKKAAKR---ADKISKQQAKG Ashgo11 MKVEIDSFSGAKIYPGRGTLFVRGDSKVFRFHSSKSASLFHQRKNPRRIAWTVLYRRHHKKGI--TEEVAKKRSRKTVK-AQRAVVGASLELI-KERRSLKPEIRKAKRDEKAKKEKKKAARKADKAKISKQQAKG Aspfu1 MRTYDDSFSGQKIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHKKGI--SEEVAKKRTRRVVK-HQRAIVGASLDVI-KERRSMRPEARAAARQQAIKKEKKASRKKAEKAKQSKQGAKG Aurde31 QKLEIDTFSGYKIYPSKGKLFVRGDGKIFRFSTSKTESLTHQRKNPRKIAWTVVYRRMHKKGI--TEE--------------------------VA---------------------------------------- Batde5 MRTEICNFSGFKIYPGKGRLYVRSDSRVFRFINRKSESYSLQRLKPSKLDWTVVFRRLHKKGI--SEETSKKRTRRTVK-VQRAVVGASLDAI-KSKRDQNPVARAAERQKAVEKEKKKAKKRAEKAKTSKQQAKG Botbo1 -KVEIDNFSLRKIYPSKGRLYVRGDSRVFRFSGAKSESLFLQRKNPRKIAWTVLYRRHHKKGL--AEETTKKRTRRTVK-HQRGIVGADLAAI-AARRNQSAQARTAARQTAIAKAEKKAK----KSKVSKQQMK- Botci1 MRTYEDSFSGAKIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLFRRQHKKGI--SEEVAKKRSRKTVK-SQRAIVGASLDVI-KERRNQRPEARSAARESAIKKEKRAAAKKATKAKVSKQGSKG Caeel MKVETCVYSGYKIHPGHGKRLVRTDGKVQIFLSGKALKGAKLRRNPRDIRWTVLYRIKNKKGTHGQEQVTRKKTKKSVQVVNRAVAGLSLDAI-LAKRNQTEDFRRQQREQAAKKDANKAAKAAANKE-TAKNVKT Canalb1 MKIEVDSFSGSKIYPGRGTLFVRGDSKIFRFQSSKSASLFQQRKNPRRISWTVLYRRHHKKGI--SEEAAKKRTRKTVK-HQRAIVGASLELI-KERRSQKPSDRKAARDSKLAKEAKKAARKAEKAKVSKQQAKG Cangl MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRVAWTVLYRRHHKKGI--TEEVAKKRSRKTVK-AQRAIVGASLELI-KERRSLKPEVRKAKRDDKAKKEKKKAARKAEKAKVSKQQAKG Capow MKLELCNFSGFKIYPGHGRRYIRSDGRSYIFINSKSESLFLQKKNPRKISWTVLYRRKHRKGA--SEEVAKKRTRRTAK-FQRSVAGASLEAI-LAKRNQKPEVRKAQRDQAVRKDAAKAKKPAAAKAAVKNVKAA Catan2 RRTELCSFSGFKIYPGHGKVFVRGDSKTFRFITSKCESYFHQRLNPRKIAWTTLYRRMHRKGI--TEEAAKKRTRRTVK-VQRAVVGASLEVI-RAKRNQSAEVRAAARAEAVKKEKKAAKN---KPKVSKQQAKG Cioin MRTELCQFSGLKIYPGHGKRYIRIDGKSFNLLSGKCQALLLAKKNPRKICWTVLYRRKHKKGT--QEEVTKKRTRRNVK-FQRAIQGASWGEI--AKRNQKPAVRKAARDQAIKKEKKKQAKKVQKAAATKNVRAS CocheC53 MRTYDDSFSGQKIYPGKGKLYIRGDSKIFRFQNGKSESLFLQRKNPRKIHWTTLYRRAHKKGI--SEEVAKKRTRRTVK-HQRAIVGASLDVI-KERRSQRPEARAAARSAAVKKEKKASAKKAEKAK-SKQGAKG Coere1 CRLEICNLSGYKIYPSRGRTFISADSKTYRFLSSKTESLFHQNKKARLLAWTPIYRRLQRKGV--SEEVAKKRTRRNVK-FNRAVVGASLEAI-NARRNEKSDVRTAARAEAVAKEQRKAKRKAARANFSKQQARG Conco1 MQLK----SKKKIYPGHGIIFVRSDSRSFRFVDSKTKSLFLQRKNPRKIHWTILFRRMHKKGI--TEESIKKRTRKTVK-AERAVVGASLEAL-AALRNQKPEVRAAARDTAIKKAKKQAKKVANKGKVSKQQAKG Conpu1 LKVEIDSFSGYRIYPSKGKLFVRGDSKVFRFASSKNASLFLQRKNPRKIAWTQVYRRMHKKGI--TEEVAKKRSRRTVK-HQRGIVGADLAAI-AAKRNQTAAVRSQQRLAAITKSEKKGTK---TKKVSKQQMKG Copci -KVEIDSFSGYRIYPSKGKLFVRGDSKVFRFSGSKSASLFLQRKNPRKIAWTQVYRRMHKKGL--TEEVTKRKSRKTVK-HQRGIVGADLAAI-AAKRNQTAAVREQQRLAAIAKSEKKSK----KAKVSKQQMKG Croqu1 MKVETCSFSGYKIYPSKGKLYVQKDSKVYRFIRSKEESLHLHRKNPRKLAWTVVFRRVRRKGV--TEEVAKKRSKKSVK-AQRGIVGADLATI-LAKRNQKPEVRTAQREEAVRKEDKKEAAKKLAGKVSKQQAKG CryneH991 MRVDRCDFTGYKVYPSRGKVYVRGDSKTFRFLSAKAESLFLQRKNPRKIAWTQVYRRMHKKGI--TEEVAKKRSRKNVK-VQRGIVGADLASI-LAKRTAKPEVRAAARQAAITKTEKRAR------KVSKQSMKG Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------- Debha1 MKVELDSFSGTKIYPGRGTLFVRGDSKIFRFQSSKSASLFHQRKNPRRISWTVLYRRQHKKGI--SEESAKRRTRKTVK-NQRAIVGASLELI-KERRSQKPSDRKAARDVKLAKEAKKAARKAEKAKVSKQQSKG Dekbr2 MKVEVDSFSGSKVYPGRGTLYVRGDSKIFRFQNSKTASLFQQRKNPRRLAWTVLYRKQHKKGI--SEVVQKKKSRKVVK-HQRAIVGASLELI-KERRALKPEQRKVKKAAAIKKDKKKERRKADKARISKQQARG Dicdi MKTSLCNYSEFKIYPARGMKFVRGDSKVFHFINTKVESLFFRKINPRDIRWSMVYRRIYKNTT--TDVSAKKKARKTKK-VERNIVGASLEVI-QQKRAQKPEVKQAAAEQAKRKEKKK--KKAAPKK-------- Dmel MKIGLCAFSGYKIYPGHGKTMVKIDGKSFTFLDKKCERSYLMKRNPRKVTWTVLYRRKHRKGI--EEEASKKRTRRTQK-FQRAIVGASLAEI-LAKRNMKPEVRKAQRDQAIKKEQKRAAKKAAAPAAAKVTQKA Enthi IKTQVCAFSGFKIPVAKGRKYVRLDLKSFTFINKKSLMQFLRKTNPRKVFWTAIYRQLNKKGQQ-NELVEKKKTRRVIK-VNRGYSGISAEEIAKRKQTQSSEVLAKKRNAAIKKEKKAAKKEAARKEKATNTYKK Falba MKVEICSYSHYRIHPGHGKRYVRLDSRSFVFITRKAEKAFLNKCNPRRTRWTVIYRRMNKKGI--SEETSRKRNRKTKK-FFRGVVGASAEVV-RAKRNQAPELREAQRNAAIKKEKSREALKAQGAAFAKTVR-- Fomme1 MKVEIDSFSGYKIYPSKGRLFVRADSKVFRFSRSKTESLFLQRKNPRKIAWTQVYRRMHKKGL--SEETTKRRTRRTVK-HQGGIVGANIQKL-LS---QSAADREKLRKQAIAKADKKAK----KDKVSKQQMKG Fusgr1 MRTYEDTFSGARIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHRKGI--SEEVAKKRTRRTVK-AQRGIVGASLDVI-KEKRNIRPEARSAARAQAIKKEKKQATKKSEKAKVSKQGAKG Galma1 MKLEIDSFSGYRIYPSKGKLFVRGDSKVFRFASSKNASLFLQRKNPRKIAWTVVYRRMHKKGI--TEEVAKKRSRKTVK-HQRGIVGADLATI-AARRNQTTAIRTQQRLAAITKTEKKTKK--EKAKVSKQQMKG Ganpr1 MKVELCNFSGYKIHPGHGKIYVRTDNRSYRFINGKSESYFLQKLKPSKLDWTVVFRRLHKKGI--TEETTKKRVKRTVK-YQRDIVGASLEAI-RAKRNMKPEVREAERKKAVQKDKKREEKKKTAAPISKMQAKG Gloin1 MKIETDSFSSNKIYPGKGKLYVRTDNRVFRFVGSKSESLFLQRKNPRKISWTQVYRRMHKKGI--TEEVAKKRTRRTVK-HQRAIVGTTWEAI-RAKRNQKPEVREAARQTALRKEKKKAKRKADKAKISKQQARG Hisca1 MRTYDDTFSGEKIYPGKGKLYVRGDGKVFRFQNGKTESLFLQRKNPRRILWTTLYRRQHRKGI--SEEVAKKRTRRTVK-SQRAVVGASLDVI-KERRSMRPEARLAARQQAIKKEKKSSKKRAEKAKQSKQGAKG Klula1 MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQSSKSASLFHQRKNPRRIAWTVLYRRHHKKGI--TEEVARKRTRKSVK-AQRAVVGASLELI-KERRSLKPEVRKAQRDEKKKKEKKKAARKSEKAKVSKQQAKG Lacbi2 IKVEIDSFSGYRIYPSKGKLFVRGDSKVFRFAGSKNASLFLQRKNPRKIAWTQVYRRMHKKGI--TEEVAKKRSRRTVK-HQRGIVGADLAAI-AAKRNQTAAVRSQQRLAAITKTEKKVK----KAKVSKQQMKG Lenti61 ---------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ---------------------------------------------------------MHKKGV--TEEVAKKRTRRTIK-SQRGVVGASVDLI-NTRRNQKPEVREAARKEHIAKEAKKTERKANRQAMSRQQAKP Mellp23 MKVETCSFSGYKIYPSKGKLYVQKDSKVFRFIRSKEESLHLHRKNPRKLAWTVVYRRVRRKGV--TEEVAKKRSKKTVK-AQRGIVGADLATI-LARRNQKPE-------------------------YRFQN--- Mnele LKLDLCNFSGYKIYPSCGIRLARTDGKIYNFVSKKARNAYLMKKNPRKIAWTVLYRRKMKKGT--EQDVAKKRARKTTK-FQRSIQGATLENI-LAKRNQKPEVRKAQREQVIRKEKIKEAKSSNKKKINKANTKS Monbr MKLELCSFSSYKIHAGHGRRLVRVDGKTFYFLGSKVESLFLQRKNPRKIAWTVLYRRKHRKGL--SEETTKRRTRRTQK-FQRAIEGVSEEKL-RELRQQKPEVRAAARQQAARKEKKQKVATKKPKAAVKNVPKK Morel2 MKIEICAFSGAKIYPGKGKIYVRVDNRSFRFVNGKAESLFLQRKNPRKISWTVLFRRMHKKGI--SEEVTKKRTRRTVK-HQRAVVGASWEAI-RAKRNQKPEVRAAARAAALRKEKKKATKKSEKAKFSKQGAKG Mucci2 --------------------------------------------------------------M--TEEVQKKRSRRTVK-HERAVVGASWDAI-RAKRNQKPDARAAARQAAISKDAKKAAKKAANP-VSKQQAKG Mydma MKLELCNFSGYKIYPGHGKRYVRSDGKLFNFLSKKSERSFHMRRNPRKISWTVLYRKKHKKGT--QEELSKKRTRRTVK-FQRAIQGASLEAI-LAKRNMKPELREAQRNQAIKKEKAKSEKKAAKKAVAKTVPKG Neucr2 MRTYDDTFSGQRIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHKKGI--SEEVAKKRSRRTVK-AQRAIVGASLEVI-KERRSMRPEARSAARLAAIKKAKKQAAKKAEKAKTSKQGAKG Orpsp11 MKIELC----FKIYPGRGKIFVRSDSKTFRFINGKCESYFLQHLKPSKLDWTVVFRRLHKKGI--SEEVAKKRTRRTVK-HQRGVVGASWEVI-KAKRMQKPEVRAAQRQQAMRKEKKRAAKKAEKAKISKQQARG Pench1 MRTYDDAFSGQKIYPGKGKLFVRGDSKIFRFQRGKSESLFLQRKNPRRIAWTVLFRRQHRKGI--SEEVAKKRTRRVVK-NQRAIVGASLDVI-KERRSQRPEAREAARKQAIKKEKKASAKKAEKAKQSKQGAKG Phybl2 MKLEICSFSGHKIYPSKGKTYVRIDSRSFRFINGKSESYFLQRLNPRKIKWTVIYRRLNKKGI--TEEIAKKRSRRTVK-HERAVAGVSWDAI-RAKRNQKPDARAAARQAAIAKEAKKATKKTTTGSVSKQGAKG Picst3 MKVEVDSFSGSKIYPGRGTLFVRGDSKVFRFQSSKSASLFHQRKNPRRISWTVLYRRQHKKGI--SEETSKRRSRKTIK-HQRAIVGASLELI-KERRNLKDSDRKAARDNKLAKEAKKAARKAEKAKVSKQQSKG Plicr1 MKVEIDSFSGFRIYPSKGKLFVRGDSKVFRFASSKNASLFLQRKNPRKIAWTQVYRRMHKKGI--TEEVAKKRSRRTVK-HQRGIVGADLAAI-AAKRNQTTAVRSQARLQAISKTEKKTK----KAKVSKQQMKG Polpo MKTGICNFSEFKIYPAKGIKFVRGDSKTFHFINGKVESLFFRKINPRDIPWTSVYRRINKNVS--VETGAKKRTKKTQK-FERSIVGASLEVI-KQKREQKPEFRAAQREAALRKEKKKSTKAAAPKATTKTAAKS Pucgr2 MKVETCSFSGYKIYPSKGKLYVQKDSKVYRFIRSKEESLHLHRKNPRKLSWTVVFRRVRRKGV--TEEVAKKRSKKSIK-AQRGIVGADLATI-LARRNQKPEVRTAQREEAIRKDEKKEAAKKSAVKVSKQQAKG Punst1 MKVEIDSFSGYKIYPSKGKLFVRGDSKIFRFATSKNESLFHQRKNPRKIAWTQVYRRMHKKGL--TEETVKKRSRKTVK-HQRGIVGADLAAI-AAKRNQTSQARLALRQAAIAKTEKKSK----KEKISKQQMKG Rhior3 --------------------------------------------------------------M--TEEVQKKRSRRTVK-HERAVVGASWDAI-RAKRNQKPDARAAARQAAIAKEAKKAAKK-ANP-VSKQQAKG Rhoto1 MKVEICNFSGYKIYPGKGKLYVRLDSKIFRFVSSKEESLFLQRKNPRKIAWTVVYRRVNKKGV--TEEVAKKRSRKTVK-HQRGVVGADAAAI-LAKRNQNPQVRAAQRAAALEKAAKK--SKKVKNPSRAQAGKG Rozal11 MKLEICNFSGYKIYPGRGRTFVR--------------AHFLAKKNPRKFLWTQVYRRLNKKGIN-ADEVAKKKTRKNVK-FQRAIAGVSVEQL-KAKRTQPPEVRAAARAEAIKKAKKAAKKKEEKAKASKAQMKR Sacce1 MKVEIDSFSGAKIYPGRGTLFVRGDSKIFRFQNSKSASLFKQRKNPRRIAWTVLFRKHHKKGI--TEEVAKKRSRKTVK-AQRPITGASLDLI-KERRSLKPEVRKANREEKLKKEKKKAARKAEKAKFSKQQAKG Salro MKLELCSFSGYKIHPGHGRTLVKADGKTFFFLGSKVESLFYQRKNPRKIAWTVLYRRKHKKGI--ATTTTKRRTRRTQK-FTRSIEGLSKERI-LELKNQSKVQRQAARQQTARRAKKQ----------------- Schco3 MKVEIDSFSGYRIYPSKGKLFVRGDSKVFRFNSSKTESLFLQRKNPRKIAWTQVYRRMHKKGI--TEEVAKKRSRRTVK-HQRGIVGADLASI-VAKRNQTAAVRAQARQAAISKTEKRAK----KPKMSKQQMK- Schpo1 MKVEVCSFSGSKVYPGAGRLFVRGDNKVFRFVNKKSESLFLQRKNPRRLSWTVLYRRMHKKGI--SEEHAKKRTRRTVK-HQRGIVGANLDVI-KEKRNQRPEVRAAARAAALKKDKKASEKKAIKAKNAKAAARH Sorma MRTYDDTFSGQRIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHKKGI--SEEVAKKRSRRTVK-AQRAIVGASLDVI-KERRSMRPEARSAARLAAIKKAKKQAAKKAEKAKTSKQGAKG Sphar ----------------------------------------MQRKNPRKISWTVLFRRKAKKGTQ-MDEKSRKKTRKAVK-SDRAIGGLTREAL-MAKRNETSEIRKARRDHISKKDKIQVAKKTNRGIVAKNNKGK Spipu1 MKIELCNFSGFKIYPGHGKVFVKGDSRTYRFINGKCESYFMQRLKPSKLDWTVVFRRLHKKGI--TEEVSKKRTRRTVK-AQRAVVGASLEAI-KAKRAQKPEVRAAQRQQALRKEKKQQKKKVEKAKFSKQQVKG Sporo1 MKVEYCNFSGYKIYPGKGKLYVRSDSKIFRFVTSKEESLFLQRKNPRKIAWTTVYRRVNKKGI--TEEVAKKRSRKTVK-AQRGIVGADLSSI-LAKRNQKPEVRQAQRDAALTKDKKKAATKSTKASQKGGKAAG Stehi1 MKVEIDSFSGFRIYPSKGRLFIRGDSKIFRFAASKNESLFLQRKNPRKIAWTQLYRRMHKKGI--TEEVAKKRSRKTVK-HQRGIVGADLAAI-AAKRNQTAQARTQARLTAITKAEKKSK----KPKVSKQGAKG Tapde11 MKVELDSFSGAKIYPGTGKLYVRVDNRIFRFFNGKSESLFLQRKNPRKIGWTVLFRRMHKKGI--SEETAKKRSRKTVK-VQRAIVGASLDDI-KKR--QRPEARAAARTESIKKDKKVSAKKAAKANVSKLQSKG Thetr MKVETCAFSGHKIYPGKGMTFIRSDARLFKFGSRKARAHYNMRHNPRKMAWTQVFRRMHKKGN--LSSFKAKKSRRVVK-FQRGFVGASLAEI-REKVQAQRDLRAVKKQAVAKKPTKAAAKKAKRAEAGRPNLGG Treme1 ---------------------------------------------------------------------------------------------------------------------------------------- Trire2 MRTYEDSFSGQRIYPGKGKIYVRGDSKVFRFVNGKSESLFLQRKNPRRIAWTVLYRRQHRKGI--SEEVAKKRTRRAVK-SQRAIVGASLEVI-KERRSMRPEARSAARAEAIRKEKKAAAKKAEKAKVSKQGAKG Umbra1 MKTEICAFSGYKIYPAKGKIYVRTDNRSFRFVNGKCESYFKQRLNPRKIDWTVVYRRMHKKGI--TEEVAKKRTRRTVK-HDRAVVGASWDAI-RAKRAQKPEVRAAARQAAVAKEAKKATKT-TN--VSKQQAKG Ustma22 MKVEICAFSQRKIYPGKGRLYVRGDNKVFRFVSSKNESLFLQRKNPRKIAWTVVYRRLHKKGV--TEEVAKKRSRKTVK-HQRGIVGASLEQI-NARRNQKPEVRAAARQAAVAKEDKKEVRKANKVKVSRQQMKG Walse1 MKVELCSFSGQKIYPSKGRLYVRLDNRVFRFANGKCESLFLQRKNPRKIAWTAFCRKLHKKGV--TEEVQKKKGKKSTK-NARGIVGLDLEAI-QAKRSQKPEVRTAARQEAIKKEAKQNATKAK----------- Zygro1 MKLEIDSFSGGKIYPGRGTLFVRGDSKIFRFQNAKSAALFKQRKNPRRIAWTVLYRRHHKKGI--TEEVAKKRSRRAVK-AQRPVVGASMELI-KERRAVKPDVRKAQREEKKKKEKRKSARRANKAKVSKQQAKG [Cluster1317.fasta_al_trimmed; alignment length = 131] Allma1 MGRMHGKGISASALPYRRTPPAWCKKLAKKGMTPSQIGVTLRDSQGVPQVKTITGNKILRILKSNGLAPEIPEDLYHL-IKKAVSVRKHMERHRKDRDSKFRLILIESRIHRLARYYKTWK---------- Ashgo11 MGRMHGKGMSSSAIPYSRNAPAWFKKYARKGLTPSQIGVLLRDAHGVTQSRVVTGNKILRILKSNGLAPEIPEDLYYL-IKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTWKYESATASALV Aspfu1 ---MHGKGISASAIPYSRSAPAWLKKLARKGATPSQIGVVLRDSHGIAQVKVVTGNKILRILKSNGLAPELPEDLYFL-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLSRYYKSWRYESATASTLV Aurde31 MGRMHGKGISSSALPYKRSPPSWLKKHARKGLTPSQIGVQLRDSQGIPQVRFLTGNKILRILKSHGLAPSIPEDLWHL-IKKAVAVRKHLEVNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLV Batde5 MGRMHGKGISSSALPYCRTVPSWLKKLAKKGMTPSQIGVILRDSHGIAQVRFVTGNKILRILKSNGLAPEIPEDLYQL-IKKAVMVRKHLERNRKDNDGKFHLILIESRIHRLSRYYKTWKYESSTASTLV Botbo1 MGRMHGKGISSSALPYRRAPPTWLKRLARKGLTPSQIGVQLRDQHGIPQTRFVTGNKILRILKSQGLGPSIPEDLWFL-IKKAVSVRKHLEVNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLV Botci1 MGRLHGKGISSSALPYSRAPPSWLKKLAKKGAAPSQIGVVLRDSHGIAQVKVVTGNKILRILKSNGLAPEIPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLSRYYKTWRYESATASTMV Caeel MGRMHGKGMAKSAIPYRRSVPSWQKKMAKKGLRPSQIGVILRDSHGVGQVRRLAGNKIFRILKSKGMAPELPEDLYHL-VKKAVAIRKHLERSRKDIDSKYRLILVESRIHRLARYYKTWKYESGTAASLV Canalb1 MGRMHGKGISSSALPYSRNAPSWFKKYARKGLTPSQIGVILRDAHGVSQAKVVTGNKILRILKSNGLAPEIPEDLYYL-IKKAVSVRKHLEKNRKDKDSKFRLILIESRIHRLARYYRTWKYESATASALV Cangl MGRMHGKGISSSAIPYSRNAPAWFKKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYL-IKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTWKYESATASALV Capow MGRMHGKGISSSALPYRRSVPAWFKKLAKKGLTPSQIGVILRDSHGVGQTRFVTGNKVLRILKAKGLAPKIPEDLYHL-IKKAVSVRKHLEKNRKDTDSKYRLILIESRIHRLARYYKRWKYESATASTLV Catan2 MGRMHGKGISSSALPYRRTPPSWCKKLAKKGMTPSQIGVTLRDSHGVPQVKNITGNKILRVLKSNGLAPEIPEDLYHL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESSNAGALV Cioin MGRMHGKGLSSSALPYRRSVPTWLKKLAKKGLRPSQIGVILRDSHGVAQVRFVTGNQILRVLKAKGLAPDLPEDIYHL-IKKAVAMRKHLERNRKDTDSKFRLILVESRIHRLGRYYKTWKYESATASALV CocheC53 MGRLHGKGISASAIPYSRNPPAWLKKLARKGATPSQIGEVLRDSHGVAQVKVVTGNKILRILKSNGLSPDIPEDLYML-IKKAVAVRKHLQTNRKDRDSKFRLILIESRIHRLSRYYKTWRYESATASTLV Coere1 MGRMYGKGISKSAIPYRRTPPSWVKKLARKGTNPSQIGVLLRDSQGIPLVSAITGTKVVRILRANGLAPEIPEDLYFL-IKKAVSVRKHLERNRKDNDAKYRLILIESRIQRLVRYYKTWEYSADTASTIV Conco1 ----------------------------------------------------------------------------------------------------------------------------------- Conpu1 MGRMHGKGISSSALPYKRSPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSQGLAPSIPEDLWHL-VKKAVAVRKHLEVNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLV Copci MGRLHGKGISSSALPYRRTPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSQGLGPSIPEDLWHL-IKKAVAVRKHLEVNRKDMDSKFRLILIESRIHRLARYYKSFKYDSATASTLI Croqu1 MGRMHHKGIAGSALPYKRTPPRWLKKLARKGMTPSQIGVVLRDSHGIAQVKSVTGAKILRILKGNGLAPELPEDLYHL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLVRYYKTFKYESATASTIV CryneH991 MGRMHGKGMSASALPYRRSQPSWSKKLARRGLSPSQIGVILRDSQGIPQVKSVTGNKILRILKTNGLAPSIPEDLYHL-IKKAVSVRKHLERNRGDKDAKFRMILIESRIHRLARYYIKFKYEAATASTLV Crypa2 MGRLHGKGISASALPYSRNPPSWLKKLAKKGATPSQIGVVLRDSHGIAQVKVVTGNKILRILKSSGLAPDIPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWRYEAATASTLV Debha1 MGRMHGKGISSSAAPYSRNAPAWFKKYARKGLTPSQIGVILRDAHGVSQAKVCTGNKILRILKSNGLAPEIPEDLYSL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYRTWKYESATASTLV Dekbr2 DGRLVGKGISSSAIPYSRNVPSWFKKYAKKGMTPSEIGVVLRDAHGVNQVKVITGNKIMRILKSNGLAPELPEDLYFL-IKKAVNVRKHLERNRKDKDAKFRLILVESRIHRLARYYRSWRYESATASALV Dicdi MGRMHGKGISGSSLPYNRKPHAWTKKLAKRGYTPSKIGSSLRDSLGVAQVKNVTGSKILRILKVNGLAPTIPEDLYHL-IKKAVTINKHLQRARKDYDGKFHLRLVESRIHRLTRPYRKWKYESNNASTLV Dmel MGRMHGKGISQSALPYRRTVPSWLKKLGKKGLTPSKIGIILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHM-IKKAVAIRKHLERNRKDKDGKFRLILVESRIHRLARYYKTWKYESSTASALV Enthi ---MYGRGISRRCIPYRRSAPSWLKKLAKKGIAPSQIGAIMRDTHGVGLVKSVTGSKVLRILKLAGLAPKIPEDLYFL-MKRAVSVRKHLEKNKKDKDAKYHLILIESKIHRLTRYYKSFKYDANTASAIV Falba MGRMYGKGKARSSLPYSRAAPSWVPHHARRGMPPSQIGSLLRDAHGVPKIQSITGNKIVRILKANGLAPEIPEDLYQL-VKKAVSIRKHLERFRKDKDAKFRLILVESRIHRLARYYRTWKYESSTASAMV Fomme1 MGRMHGKGISSSALPYRRTPPSWLKKLARKGMTPSQIGVLLRDSHGIPQVRFVTGNKILRILKSNGLAPAIPEDLWHL-VKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLI Fusgr1 MGRLHGKGISASALPYSRSSPAWLKKLARKGATPSQIGVILRDSHGIAQVKHVTGNRILRILKSSGLAPELPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESATASTIV Galma1 MGRMHGKGISSSALPYRRAPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSQGLGPSIPEDLWHL-IKKAVAVRKHLEVNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLV Ganpr1 MGRLHGKGISSSALPYRRTPPSWLKKLAKKGATPSQIGVQLRDAHGIAQVRFVTGNKILRILKANGMAPEIPEDLYHL-IKKAVAIRKHLERNRKDTDGKFRLILVESRIHRLARYYKTWKYESSTASALV Gloin1 MGRMHGKGISDSALPYRRTQPTWLKKFAKKGMTPSQIGVQLRDSHGIAQVKSVTGNKILRILKSNGLAPEIPEDLYHL-IKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKKWK---------- Hisca1 MGRLHGKGISASAIPYSRNPPSWLKKLAKKGATPSQIGVILRDSHGIAQVKVVTGNKILRILKSNGLAPEIPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLSRYYKSWKYESATANTLV Klula1 MGRMHGKGMSSSAIPYSRNAPAWFKKYARKGLTPSQIGVLLRDAHGVTQAKVITGNKILRILKSNGLAPEIPEDLYFL-IKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTWKYESATASALV Lacbi2 MGRMHGKGISSSALPYRRAPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSQGLGPSIPEDLWHL-IKKAVAVRKHLEVNRKDKDSKFRLILIESRIHRLARYYKTFKYDAATASTLI Lenti61 MGRMHGKGISSSALPYRRAPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSSGLAPQIPEDLYYL-VKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTFKYESATASTLV Malgl1 MGRMHGKGISKSALPYSRTPPSWLKKLARKGVTPSQIGSQLRDSQGIAQVRYVTGSKILRILKSEGLAPEIPEDLYHL-IKRAVSVRKHLERNRKDMDSKFRLILIESRIHRLSRYYKTFKYESSTASTLV Mellp23 MGRMHHKGIAGSALPYKRTPPRWLKKLARKGMTPSQIGVVLRDSHGIAQVKSVTGAKILRILKGSGLAPELPEDLYHL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLVRYYKTFKYESATASTIV Mnele MVRMHGKGIAQSALPYKRSVPTWQKKLSKKGLTPSQIGVILRDSHGVNQIKHLTGTKILRILRAKGLASKIPEDLYHL-IKKAVAIRKHLEKNRQDKDSKYRLILIESRVHKLARYYKTWKYESATASALV Monbr MGRMHGKGISRSAAPYVRTAPAWLKNLARKGMTPSKIGVVLRDSRGIASVKSLTGTKILRILKGRGLAPELPEDLYCL-IKKAVSMRKHLDKNRKDKDCKFRLILVESRIHRLARYYKGFKYQSATASALV Morel2 MGRMHGKGISSSALPYKRSPPSWLKKLAKKGMTPSQIGVILRDSQGIAQVKNVTGNKILRILKSNGLAPEIPEDLYHL-IKKAVAVRKHLERNRKDCDGKFRLILIESRIHRLARYYKTWKYESATASALV Mucci2 MGRMYGKGISGSALPYRRTPASWVKKNAKKGLSPAQIGVLLRDSNGIPQVKSITGNKILRILKSNGLAPEVPEDLYHL-IKKAVSIRKHLERNRKDKDSKYRLILIESRIHRLARYYKTWKYESATASAMV Mydma MGRMHGKGISGSALPYRRSVPTWLKKHAKKGLTPSQIGVILRDSHGVAQVRYVTGNKILRILKAKGLAPTLPEDLHCL-IKKAVSVRKHLERNRKDCDAKFHLILIEARIHRLARYYKTWKYESSTASALV Neucr2 MGRMHGKGISASAIPYSRNPPSWLKKLAKKGATPSQIGVILRDSHGIAQVKVVTGNKILRILKSNGLAPDLPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESSTASTIV Orpsp11 ---MHGKGIASSALPYKRTPPSWLKKFAKKGMTPSQIGVVLRDSHGIAQVKSVTGNKILRILKSNGLAPELPEDLYFL-IKKAVAVRKHLERNRKDSEAKFRLILIESRIHRLARYYKTWK---------- Pench1 MVRLHGKGIAASAIPYSRTTPAWLKKLAKKGATPSQIGVVLRDSHGVAQVKIVTGNKILRILKSNGLAPELPEDLYFL-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLSRYYKAWRYESATASTLV Phybl2 MGRLHGKGISSSALPYRRSPPSWLKKSAKKGLCPAQIGVVLRDSHGIPQVNRVTGNKILRILKKNGLAPEIPEDLYFL-IKKAVSVRKHMERNRKDMDSKYRLILIESRIHRLARYYKTWK---------- Picst3 MGRMHGKGISSSAVPYSRNAPAWFKKYARKGLTPSQIGVILRDAHGVSQTKIVTGNKILRILKSNGLAPEIPEDLYFL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYRTWKYESATASALV Plicr1 MGRMHGKGISSSALPYRRAPPTWLKKLARKGLTPSQIGVILRDSHGIPQVRFVTGNKILRILKSQGLAPSIPEDLWHL-VKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLI Polpo MGRMHGKGISSSALPYNRKPHSWTKLLAKRGYTPSQIGVLLRDSHGIAQVKNITGSKILRILKVNGLAPAIPEDLFHL-IKKAVTINKHLQRAHKDYDGKFNLRLVESRIHRLSRPYRKWKYEAATASTLV Pucgr2 MGRMHHKGIAGSALPYKRTPARWLKKLARKGMTPSQIGVVLRDSHGIAQVKSVTGAKILRILKGNGLAPEIPEDLYHL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLTRYYKTFKYESATASTLV Punst1 MGRMHGKGISSSALPYRRAPPTWLKKLARKGLTPSQIGVTLRDSHGVPQVRFLTGQKILRILKSHGLAPGIPEDLWHL-VKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKSFKYDSATASTLI Rhior3 MGRMHGKGISSSALPYRRTPPSWVKKNAKKGLTPSQIGVILRDSYGIPQVRSITGNKVLRILKSSGLAPEVPEDLYHL-IKKAVSIRKHLERNRKDKDSKYRLILIESRIHRLARYYKTWKYESATASAMV Rhoto1 MGRMHHKGIAGSALPYKRSAPRWLKKLARKGLTPSQIGVVLRDSHGVAQVKSVTGNKILRVLKSNGLAPQIPEDLYCL-IKKAVQVRKHLERNRNDKDSKFRLILIESRIHRLARYYRTFKYEAASASTMI Rozal11 MG---RKGISDSALPYRRTPPSWLKKYAKKGLTPSQIGVLLRDQHGIAQTRFVTGNKVLRILKANGLAPEIPEDLYQL-IKKAVAVRKHLERFRKDKDSKFRLILIESRIHRLARYYKTFKYESATASTLV Sacce1 MGRMHGKGISSSAIPYSRNAPAWFKKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYL-IKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTWKYESATASALV Salro MGRMHGKGISRSSRPFVRTAPSWLKKLARKGHTPSKIGVILRDSRGISSTKAITGTKVLRILKAAGLAPEIPEDLYCL-IKKAVAMRKHLQENRNDKDCKFRLILVESRIHRLSRYYRTFKYESATASALV Schco3 MGRMHGKGISGSALPYRRAPPAWLKKLARKGMTPSQIGVTLRDAHGIPQVRFVTGNKILRILKSQGLGPSIPEDLWYL-IKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLV Schpo1 MGRMHGKGIASSALPYVRSPPAWCKKFSKKGMSPSQIGVTLRDSHGIPQVRFITGQKIMRILKANGLAPELPEDLYNL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYRKWKYESATASALV Sorma MGRLHGKGISASAIPYSRQPPS---KLAKKGATPSQIGVILRDSHGVAQVKVVT-----------GLAPDLPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESSTASTIV Sphar MVRMHGKGISRSSLPYRRSVPSWLKKLARKGLTPSQIGVILRDSHGVAKVDRVTGSKILRILRAKGLAPDTPEDLYCL-IKKAVSVRKHLDRNRKDKDSKFRLILIEARIHRLARYYKRWKYDSATASTLV Spipu1 MGRMHGKGIASSALPYRRTPPSWLKKFAKKGLTPSQIGVILRDQHGIAQVKNVTGNKILRILKSNGLAPEIPEDLYHL-IKKAVAVRKHLERNRKDADSKFRLILIESRIHRLARYYKKWKYESSTASALV Sporo1 MGRMHHKGIAGSALPYKRSAPRWLKKLARKGLTPSQIGVILRDSHGVAQVKSVTGNKILRILKTNGLAPQIPEDLYMLXLKKAVQVRKHLERNRHDKDSKFRLILIESRIHRLARYYKTFKYEAATASTLV Stehi1 MGRMHGKGISSSALPYRRTPPSWLKKLARKGLTPSQIGVTLRDSHGIPQVRFVTGNKILRILKSNGLAPSIPEDLWHL-VKKAVAVRKHLETNRKDKDSKFRLILIESRIHRLARYYKTFKYDSATASTLI Tapde11 ----------------------------------------------------------------------------------------------------------------------------------- Thetr MVRMHGRGISRSALPYRTAPPSWLKHAAKKGSTPSQIGVMLRDSHGVARVKNVTGAKVLRILKANGMAPEIPEDLYHL-IKKAVSIRRHLERNRKDRDAKFRLVLVESRIHRLSRYYKKFKYDSATAATLV Treme1 MGRMHGKGISASALPYRRSAPSWSKKLARRGLTPSQIGVTLRDSQGIAQIKSVTGNKILRILKTNGLAPSIPEDLYHL-IKKAVSVRKHLERNRGDKDAKFRMILIESRIHRLARYYIRFKYEAASASTLV Trire2 MGRLHGKGISSSAIPYSRSAPSWLKKLAKKGATPSQIGVVLRDSHGISQVKVVTGNRILRILKSNGLAPDIPEDLYML-IKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESATASTIV Umbra1 MGRMHGKGISSSALPYRRTPPSWVKKLAKKGLSPSQIGVILRDSHGIPQVKGVTGNKVLRILKSNGLAPEIPEDLYQL-IKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTWKYESATASAMV Ustma22 MGRMHGKGISASALPYRRTPPSWLKKLARKGMTPSQIGVQLRDSQGIAQVRFVTGNKILRILKSQGLAPQIPEDLYHL-IKKAVSVRKHLERNRKDMDSKFRLILIESRIHRLARYYKTFKYEAATASTLV Walse1 MGRMHSKGISSSALPYRRNPPSWLKKLARKGLSPSQIGVILRDQHGVPQTRFVTGNKILRILKSSGLAPELPEDLYCL-IKKAVSVRKHLERNRNDKDSKFRLICIESRIHRLTRYYRRFKYESSTASTLV Zygro1 MGRMHGKGISSSAIPYSRNAPSWFKKYARKGLTPSQIGVLLRDAHGVTQARVITGNKIMRILKSNGLAPEIPEDLYYL-IKKAVSVRKHLERNRKDKDAKFRLILIESRIHRLARYYRTWKYESATASALV [Cluster1328.fasta_al_trimmed; alignment length = 330] Allma1 ATVTAPVNIAVIK-YWGKRDESLILPTNSSLSATLSQDILHSKTTAADPSFDTLWLNGTPEMAASKRLANVVTALRAKRAA-LESLPKMSIRVVSENNFPTAAGLASSASGFAALVFALANLYQLPSALARLGSGSACRSLFGGFVAWEMGDGRD--SVAVP--VAPATHWTDLEALVLVVHDGRKGVSSTSGMQTTVKTSALAQE---------------------------------------------------------------------------------------RR----------------------------------- Ashgo11 ASTTAPVNIATLK-YWGKRDSMLNLPTNSSISVTLSQEDLRTLTSATGPELDRLWLNGKPEL-GNARTQQCLADLRALRRA-LEDLPRMSLHIVSENNFPTAAGLASSAAGFAALVVAVAKLYGLPSKIARKGSGSACRSLYGGYVAWEMGDGSD--SRAVQ--IADVEHWPEMRAAILVVSADRKDTPSTSGMQQTVHTSDLFKERVATVVPRRYGEMAAAIRARDFATFARLTMQDSNSFHATCLDSFPPIFYMNDTSRRIVKLCHLINE-NETIVAYTFDAGPNAVLYYLAELCGFLRGVARLIFTKVGPGP--QSSLIDPETGLPR Aspfu1 ATTTAPVNIAVIK-YWGKRDASLNLPTNSSLSVTLSQRSLRTLTTACSAIYDELILNGKPQIQTSKRTLACLSNLRSLRQA-LESLPKLSLRIVSENNFPTAAGLASSAAGFAALVRAVADLYQLPSRIARQGSGSACRSLMGGYVAWRAGDGSD--SLAEE--VAPASHWPEMRAIILVVSAEKKDVPSTEGMQTTVATSSLFATRAASVVPERMAAIETAIQNKDFATFAEITMRDSNSFHATCLDSWPPIFYMNDVSRAAVRLVHDINR-GRTVCAYTFDAGPNAVIYYLEKVAGTINGISRVILTGVGEGP--IDHLVSAT-GDIL Aurde31 ATASAPVNIACIK-YWGKRDTGLILPTNSSLSVTLDQDNLCATTTSADPSFDTLWLNGKEEIKPGGRTAVCIDELRRLRQL-AENEPKISLHIASYNNFPTAAGLASSAAGFAALVSSIARLYSLDSLIARQGSGSACRSLMGGFVAWEMGDGSD--SLAVQ--VAPREHWPEMHALICVVSDAKKGTSSTSGMQRTVETSPLLQHRIAHVVPQRMAEIQKAILARDFPAFASLTMRDSNSFHAVCLDTDPPIFYMNDVSRALVALVVEYNRAGETRAAYTYDAGPNCVIYVLEKVANLVGSVKGLIHTRVGDGPRSYDHLLDAQ-GQPK Batde5 VTCSAPVNIAVVK-YWGKRDTQLLLPTNSSLSVTLSQDHLRSTTTITDASLDRLWLNHSEVIAASSRLRNVLAEARRLRRT-VETLPILSLHIASVNNFPTAAGLASSASGFACMVYALDQLFELNSRLARIGSGSACRSLFGGFVAWDMGDGLD--SVAVQ--VDTELHWPDLEALILVVSDAQKDTGSTVGMQRTVETSALLQHRIHHVVPDRMVEMTNAIHCKDFDTFAKLTMQDSNQFHAVCLDTFPPISYMNDISRAIVRLITAYNDLKGYRVAYTFDAGPNAVLYLPRKVLGLIGSLQRIISTHVGDGPRLLVSLLDQS-G--- Botbo1 ATASAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADASFDRLWLNGTEEIKEGGRMATCIAELKTLRKE-VEHAPKLSVHISSFNNFPTAAGLASSASGFAALVASLAQLYALPSRIARQGSGSACRSLFGGFVAWEMGDGSD--SFAVE--VAPQSHWPEMHALICVVSDDKKGTSSTAGMQRTVQTSELLQHRIKHVVPARMDAIKKAITAKDFDTFATITMQDSNQFHAVALDTDPPIFYMNDVSRSIIALIVELNRAKGIKAAYTYDAGPNAVIYALQHIVNLTGAVKNLIHTRVGDGPRALESLLGSD-GFPK Botci1 ASTTAPVNIAVVK-YWGKRDAKLNLPTNSSISVTLSQDDLRTHTTACSSTFDSLLLNGSSQI-SNARTQACFRDLRSLRSA-LESLPKLSLRIISENNFPTAAGLASSAAGFAALVRAIANLYELQSKIARQGSGSACRSLFGGYVAWEMGDGSD--SVAVE--VAPASHWPTMRALILVVSAEKKGVSSTSGMQITVATSKLFKQRAENVVPEHMKEMERAIKEKDFEGFAKVTMMESNSFHATCLDTFPPIFYLNDVSRAAIRAVEDINN-GKTVAAYTFDAGPNAVIYFEEEVAGALDGVSRVILTGVGGGP--EKHLSA------- Caeel A---------------------------------------------------TVEINGKSVLSSNKRYQTVFDEALRLQRKRKENDPPPIFHVTSTTNFPVAAGLASSAAGFAAIALAIQRILRLDNRLARIGSGSACRSMYGGLVHWRKGDGSD--CLAVR--TEAAANWEDLYCIILVFDDGRKKVGSSEGMRRSRETSQLLKHRIESIVPQRIQQIQEAYTSRNFEQLARVIMADSNQFHAVCMDSTPPIRYLNEASWQLIDTVEEFNI-GGIRAAYTFDAGPNACVIVQKEFLKAVTKCSKLIMSPMGGGPQE------------- Canalb1 ASVTAPVNIATLK-YWGKRDKSLNLPTNSSISVTLSQDDLRTLTTAASESFDQLWLNGKLEL-DTPRTQACLADLRKLRAS-IEDTPKLSLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYELPSKIARKGSGSACRSLFGGFVAWEMGDGQD--SKAVE--IAPLEHWPSLRAVILVVSDDKKDTPSTTGMQSTVATSDLFAHRIAEVVPQRFEAMKKAILDKDFPKFAELTMKDSNSFHAVCLDSYPPIFYLNDTSKKIIKMVETINQ---VVAAYTFDAGPNAVIYYDEAVLSLLAGVSRIIQTSIGPGP--QESLTK------- Cangl ASTTAPVNIATLK-YWGKRDAKLNLPTNSSISVTLAQEDLRTLTSATSSEFDKLWLNGKEEL-SSERTQNCLADLRALRRQ-LESLPPMSLHIVSENNFPTAAGLASSAAGFAALVMAIAKLYELPSKIARKGSGSACRSLFGGYVAWEMGDGSD--SKAVE--VAPLEHWPNMKAAVLVVSADKKDTPSTSGMQLTVNTSDLFKERITNVVPKRFEAMKKAILDKDFPTFAELTMKDSNSFHATCLDSFPPIFYINDTSKKIIKLCHLINE-GETIVAYTYDAGPNSVLYYLEELFAFIENVSRVILTRVGPGP--QECLINEETGLPK Capow VTCTAPVNIAVIK-YWGKRDEELILPINSSLSGTLSQDQLHARTSVARADFDAIWLNGKQEI-ENPRLQNCLREIRKLAAA---QGAPLPVHICSVNNFPTAAGLASSAAGYACLVYALAQLYKVGTKLARVGSGSACRSIYGGWVRWVMGDGSD--SIAEQ--VVDEHHWPEIEVLILVVSDHKKTTSSTAGMQTTVETSSLVKHRADKVVPQRMEDIQNAIRARDFETFGRITMQDSNQFHAVCLDTYPPITYLNDVSRGIIDMLTKYNA-GKIQAAYTFDAGPNAVIYLPREVVNLVDSLKYVMHTRVGSGPQVLDCLLDAS-GNPR Catan2 ATATAPVNIAVIK-YWGKRDQSLILPTNSSLSLTLSQDILHSKTSAAAASVDTLWLNGTPEVSSSTRLRKVIAALRDLRRA-KEALPKISLRIVSENNFPTAAGLASSASGFAALVAVVAHLYDVASSLARLGSGSACRSLYGGFVAWEMGDGSD--SVAVQ--VAPESHWPEIEALVLVVHDGKKGISSTSGMQTTVDTSPLAAHRFAHVVPERMEAMKRAIHTKDFDSFAELTMRDSNQFHAVCLDTFPPIFYLNDVSRAIIQLITDYNATGKFKVAYTYDAGPNTVLYLPRRVLALVGGIKRILHSKVGDGPRFLVSLVSTQ-GEPL Cioin ITCCAPINIAIIK-YWGKLCEVENLPLNSSFSITLNYHDLCTTTTVTAPSYDQVYVNDLWQINENPRLKVCFEEMRRLARKQAIAAKELMIHVQSVNNFPTKAGLASSASGYAALTFALGQLLGVKSGVARRGSGSACRSMCGGFVEWLKSESKN--STAKQ--FVDETHWPELRVFILVVSSKQKSFGSTVGMQRSVETSALLKHRIENIVPHRIKVLKQAVLEKDFCLFAEICMKESNQLHAICMDTFPPLRYLNNVSEKIMNFVYSYNE-GSTRVAYTFDAGPNAFLFTLAPLANQIGLIEYVICTKPGPGPQIV------------ CocheC53 ASTTAPVNIAVIK-YWGKRDPKLNLPTNSSLSVTLAQSDLRTHTTACSSSYDTLLLNGQSQV-SGARTQACFRELRALRRE-LESLPKLALRIVSENNFPTAAGLASSAAGFAALVRAIANLYELPSRIARQGSGSACRSLFGGYVGWEQGDGSD--SVAFQ--VAPASHWPNMRAVVLVVSAAKKGVSSTTGMQTTVATSSLFQSRASETVPRRMKEMQDAIQNKDFEAFGKVTMMDSNSFHATCLDTFPPIFYLNDVSRAAIKVVESINA-GKIIAAYTFDAGPNAVVYYLEEVAGLFEGVSRVILTGVGEGP--VESLIDEK-GEPV Coere1 ATVSAPVNIAVIK-YWGKRDAGLILPTNSSLSVTLSQDHLCTRTTVAAAEFDRLWLNGVEEVTASARLCNVISTARKLRAA-VEAAPRLSLHVCSENNFPTAAGLASSASGYAALVSALGTLFKLPSRVARVGSGSACRSILGGFVAWQAGDGSD--SLAEQ--VAARAHWPQLQALVLVVSDRKKTVSSTAGMQTTVATSPLFAERVRNVVPRRMAVMRAAIAARDFAAFATLTMQDSNQFHAVCQDTFPPIAYMNDTSHAITNLVHAFNT-GRVAAAYTYDAGPNAVIFALHDLVQLLGSVRRIIHTEVGDGPRVLESLLNHA-GMPK Conco1 -TCTAPVNIAVVK-YWGKRDEKLILPTNSSLSGTLSQDQLQTRTTIVSSEFDRLWLNGKEEVANSKRLQNCLNETRKLRKE-FE--EKLSIHACSVNNFPTAAGLASSASGYACFVFTLCKLFDLPSKIARVGSGSACRSLFGGFVAWEMGDGSD--SRAVQ--IAPETHWPEVEALILVVSDAKKATSSTVGMQTTVNTSPLLQHRIKNVVPERMEQMKKAILDRDFESFALLTMQDSNQFHAVCLDTYPPISYMNDVSRAIVRLVTEFNK-G-VRVAYTYDAGPNAVLYASRDIIPIIDSIKNILHTKLGDGPRVAVTLLGQD-GLPL Conpu1 ATVTAPVNIAVVK-YWGKRDTKLHLPTNSSLSVTLDQDYLCSTTTAADAAFDRLWLNGNEEIAGNGRFERCISEMRALRTK-YEDATKLALRIASHNSFPTAAGLASSASGYAALTAALAALYELNSKLARQGSGSACRSLMGGFVAWDMGDGRD--SAARQ--IADEAHWPDMHAIICVASAAKKAVSSTAGMQATVATSPLHAARCGVPAPGTMAQMQDAIRRKDFDTFAEVAMAESNQFHAVALDTRPPIRYMNDTSWNIVSAITAYNTLRKYAAAYTFDAGPNAVVYALQSIIELLGEVKRLIHTKVGPGPRVYRAVLGAD-GYPK Copci ATASAPVNIAVIK-YWGKRDTSLILPTNSSLSVTLSQDHLRSTTTSASSSFDRLWLNGQEDIKPGSRLETCIREMKKLRKELVENAPKLSVHIASYNNFPTAAGLASSASGFAALVSSLAHLYTLTSLIARQGSGSACRSLFGGFVAWEMGTGTD--SLAVQ--IADEAHWPEMHALICVVSDDKKGTSSTAGMQRTVETSTLLQHRIKDVVPRRMDEMIRAIKEKDFDSFARITMADSNSFHAVALDTEPPIFYMNDVSRAIIALIVELNRVEGYKAAYTYDAGPNAVIYTLDKVIQLIGAVKGLIHTKVGDGPRRLESLLGKD-GFPK Croqu1 VTCCAPVNIAVIK-YWGKRNKELILPTNSSLSVTLDQDDLRSTTTALIE--DQLWLNGSQVITPDSRLARCLAELRRLRAQ-VEELPE-SLVIVSENNFPTAAGLASSASGFAALTFTVAQLFELPSCIARQGSGSACRSLLGGFVAWDMGNGED--SGARM--VAPQAHWPDLEAVICVVSDAKKGTSSTGGMERTVQTSPLLQHRISSVVPARMAEMESAILSKDFDKFSELTIADSNQFHAVCLDTNPPIFYLNDVSRAIISVIEELNRSKGTVAAYTFDAGPNAVIYAPRSIVSTLGSVHRLICTSVGDGPRVLKGLITLE-GSPR CryneH991 ATASAPVNIACIK-YWGKRDTRLILPTNSSLSVTLDQDHLRSTTTSADASFDRLWLNGREEIKEGGRLAVCIKELRAWRKE-MENLPKLSLRIASYNNFPTAAGLASSASGLAALVASLASLYSLPSLVARQGSGSACRSLFGGFVAWREGAGSD--SLAEE--VAPREHWPEMHALICVVSDAKKGTSSTSGMQKTVETSTLLQERLR-VVPKRMDAISQAIKARDFAEFAKLTMADSNSFHAVCLDTAPPIFYLNDVSRAIIAVVEELNRAGEIIAAYTFDAGPNAVIYTLEKVLGAIGAVKGLIHTRVGDGPRVLDSLLGEN-GVPK Crypa2 ASTTAPVNIAVVK-YWGKRDAKLNLPTNSSLSVTLSQSDLRTLTTACSASYDSLLLNGSPSV-TGARTQACFRALRSRRAA-IESLPKLSLRLVSENNFPTAAGLASSAAGFAAFVRAVADLYELPSLIARQGSGSACRSLFGGYVAWRMGDGSD--SLADL--VAEASHWPEMRALILVVSAAKKGVSSTSGMQQTVATSGLFKQRVAEVVPKNMDLMEKAIKDKDFALFAEVTMRDSNSFHASCADTYPPIFYMNDVSKAAVRAVEKINE-GRTVAAYTFDAGPNCVVYYLEKVVGSFTGVSRVIMTGVGEGP--QEYLVTEN-GELV Debha1 SSATAPVNIATLK-YWGKRDKSLNLPTNSSISVTLSQNDLRTLTSVASEDFDKLWLNGKLEL-ESERTKACLADLRTLRKE-LESIPKLSVHIVSENNFPTAAGLASSAAGFAALVVSIAKLYELPSKIARKGSGSACRSLFGGYVAWEMGNGED--SKAVE--VAPLSHWPNMKAAILVVSDDKKDTPSTSGMQTTVATSDLFQWRIKEVVPKRFDDMKDSILRKDFATFGDLTMKDSNSFHAVCLDSTPPIFYLNDTSKKIIKLIHELNK-GKIIAAYTFDAGPNAVIYYEQEVLGVIKGVSKIILTEVGQGP--QESLINDK-GLPK Dekbr2 VTVTAPVNIATLK-YWGKRDRFLNLPTNSSISVTLSQDDLKTTTSVYSKNFDALYLNGNEEL-SSPRQQSCLKSLRKCRIE-KESLDKIALHIVSVNNFPTAAGLASSAAGYAAMVYSIAKLYQLDSKIARQGSGSACRSLYGGFVAWEMGNGSD--SKAVQ--IAPRAHWPGIRAAILVVSAAKKEVPSTGGMQSTVKTSDLFDYRVKQVVPARYEEMKKAILAKDFGVFAELTMKDSNSFHAVCLDSYPPIFYMNDTSKRIVKVITTINE-GRNVAAYTFDAGPNAVIYYEEKVLGTLKGVSRVILTSVGEGP--TESILNPDTGLPK Dicdi VTCTAPVNIAVIK-YWGKRDENIILPLNSSLSGTLHQDDLKTTTTIASEDYDELYLNGKKEI-NAVRYQNVLKMIRSRAT-------KLMVHIASINNFPTAAGLASSASGYCCLVFTLAQMYGVDSGIARLGSGSACRSMYGGFVKWEMGDGSD--SIAVQ--VQPESHWPDMNIIVLVVNDKKKETSSTDGMQKSAATSVMMKERCAVTVPNRMRDIEEAINKKDFQTFGDITMKDSDDFHEVCATTTPPIYYLNDTSRYIMNLIHRYNK-GSIKCAYTFDAGPNACIYLPAEVLSLFNSLKYILHTKVGPGPQILSLIDNTT-GLPK Dmel VTCVAPVNIALIK-YWGKRHEELILPVNDSISMTLSTDELCAKTTVASESFNRMWLNGEEVFEESSRLQRCLNEVHRLAVA------VPPLHIASVNNFPTAAGLASSAAGYACLVYSLSRLYDIPTTVARQGSGSACRSLYGGFVQWHRGDGSD--SVARQ--IAPSDHWPNMHVLILVVNDARKKTASTRGMQQAVKTSQLIKHRVDQVVPDRIIRLREAIASHDFQAFAEITMKDSNQFHAIALDTYPPCVYMNDVSHSIVSFVHDYNE-GSYHAAYTFDAGPNACLYVLAELLSAINAFRYIIHTKVGEGPKELSLLIN---GLPL Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba VTCTAPVNIAIIK-YWGKRDVERNLPTNGSISVTLSQKALRTTTSVLSPEHDRLWLNGKEDSRAGTRLAKVFDLIRRLARQ------PRAAHVASHNSFPTAAGLASSASGFACLAFSLAKAYGLQSGIARQGSGSACRSLFGGYVAWEHGEDEDFGSHAVQ--LADEGHWPEMAIFVHIVSAEKKTVSSTSGMQTTVRTSPLHTYRAAHVVPARMEAMRQAIAARDFDAFAKLTMEDSNQFHATCLDTYPPIFYLNDTSRDLIQLVHRFNE-GAIMAAYTYDAGPNAVVYIKREWLDAVGAVDGLLFSLPGGGPEVIASLLDAA-GMPK Fomme1 ATASAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADPSFDRLWLNGKEEIKEGGRLATCIAEMRRLRRE-VET-PKIAVHIASHNNFPTAAGLASSASGFAALVSSLAALYELPSLIARQGSGSACRSLFGGFVAWEMGDGSD--SFAVE--VAPREHWPNLHALICVVSDDKKGTSSTSGMQRTVETSTLLQHRIKEVVPARMRAISEAIKARDFEKFARITMADSNQFHAVALDTEPPIFYMNDVSRSIVALIVEYNRAGPVKAAYTYDAGPNAVIYAPEEIVDIIGAVKGLIHTRVGDGPRVLEALLNAE-GLPK Fusgr1 ASTTAPVNIAVVK-YWGKRDAKLNLPTNSSLSVTLSQDDLRTLTTACSSTFDSLTLNGESSI-SGARTQACFRELRSRRAA-LESLPKLSLKIVSENNFPTAAGLASSAAGFAALVQAIAFLYELPSLIARQGSGSACRSLFGGYVAWRMGDGSD--SKADL--VAPASHWPEMRALILVASAAKKGVSSTSGMQQTVATSGLFKERITNVVPANMALMEEAIKDKDFPKFAEVTMRESNSFHATCADTYPPIFYMNDISRAAIRAVECINE-GRTVAAYTFDAGPNCVIYYEEKIVGAFEGVSRVISTGVGEGP--VEFLA-------- Galma1 ATASAPVNIAVIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADPSFDQLWLNGKVDIKAGGRLATCISEMKRLRKELVENEPKLSVHIASYNNFPTAAGLASSASGFAALVASLAHLYALTSLIARQGSGSACRSLFGGFVAWQMGAGSD--SLAVQ--VAPQEHWPQMHALICVVSDDKKGTSSTSGMQRTVETSALLQHRIKHVVPERMGAISKAILAKDFDTFAKITMADSNQFHAVALDTEPPIFYMNDVSRTIIALVVEYNRLGGYKAAYTYDAGPNAVIYALEEIVQLVGAVKSLIHTRVGDGPRKLEGLLAEN-GLPK Ganpr1 VTVCAPVNIAVIK-YWGKRSVSLNLPTNSSLSVTLHTDDLRSTTTACSPLFDILWLNGKKEVAKAKRFAAAVEEARKMRRE-RESLPKLSIRIASVNNFPTAAGLASSASGYAALVFALKELYDLPSRAARLGSGSACRSVFGGFVAWRAGDGLD--SVAEQ--VADDGHWPDVEALILVASDAKKDVGSTEGMQGTVATSELFPARVANSVPKRMKQMEKAIASRDFDLFAETTMRDSNQFHATCLDTYPPVFYMNDASRAVVRLVHAYNDLRGYRCAYTFDAGPNAVIYTLRSLAAIVGAIRRAIHTKVGPGPTVLVSLLRTD-GNII Gloin1 RTSTGPVNIAVIK-YWGKRDTELILPTNSSISITLSQDQLRSKTTIASPKFTRLWLNGVEELDNNIRLQNCLRATKKLRKE-YENVQPISLHICSENNFPTAAGLASSASGFACLVYTLSQLYELPSKIARQGSGSACRSLFGGFVNWQMGDGSD--SQALQ--IAPHDHWPELAALICIVSDAKKGTSSTEGMQNTVKTSTLLQYRINNVVPERMKSMTNAILHKNFNKFAEITMKDSNQFHACCLDTFPPIFYLNDVSRSIIRVITEYNNTE-FKAAYTFDAGPNAVIYALKQIINIIDSVKQILHTRIGNGPRINDSLLNPN-GYPK Hisca1 --------MCFVRLYWGKRDAVLNLPTNSSLSVTLSQSSLRAYTTACSPTYDSLTLNSQPQIKDSKRTLACLSDLRSLRRE-LESLPKLSLRIVSENNFPTAAGLASSAAGFAALVRAVANLYELPSRIARQGSGSACRSMMGGYVAWRTGDGSD--SFAEE--VAPASHWPEMRALILVVSDAKKDVPSTQGMQATVATSTLFRTRAETVVPARMAAIESAIKNRDFASFAEITMKDSNNFHATNLDTWPPTFYLNDVSRAAIRLVHDINR-GETICAYTFDAGPNAVIYYLDKVIGTFGGVNTVILTGVGGGP--QQHLVSET-GEIL Klula1 ASTTAPVNIATLK-YWGKRDKVLNLPTNSSISVTLSQEDLRTLTTATSPDFDQLWLNGKEEL-ASERTQHCLQDLRQLRRE-LESLPTFSLHIASENNFPTAAGLASSAAGFAALIKAIAKLYELPSKIARKGSGSACRSLFGGYVAWEMGDGSD--SKAVE--IGSLNHWPEMKAAILVVSADKKDTPSTSGMQLTVKTSDLFQERINNVVPKRFEQMKKSILEKDFPTFAELTMKDSNSFHATCLDSYPPIFYLNDTSKKVIKLCHAINE-NETVVAYTFDAGPNAVLYYLEQLFAFLQGVTRVILTRVGPGP--QLSLIDSATGLPS Lacbi2 ATASAPVNIAVIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADPSFDTLWLNGKEDIKPGGRLATCISELKRLRQATVESAPKLSVHIASYNNFPTAAGLASSASGFAALVASLAQLYALPSIIARQGSGSACRSLYGGFVAWQEGDGSD--SLAVQ--VAPQSHWPEIHALICVVSDDKKGTSSTSGMQLTVETSTLLQHRIKAVVPQRMKDISKAILEKDFDTFARITMADSNQFHAVALDTEPPIFYMNDVSRAIIAVIVEYNRLQGYKAAYTYDAGPNAVIYAEEKIIQLIGAVKGLIHTRVGDGPRALEALLGPE-GTPK Lenti61 ATASAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADPSFDRLWLNGVEEIKDGGRLATCIKEMKALRKQ-LESLPKISVHISSRNNFPTAAGLASSASGFAALVASLSALYQLSSLIARQGSGSACRSLFGGFVAWQMGDGAD--SYAVE--IAPREHWPDIHALICVVNDEKKGTSSTSGMQRTVETSPLLQHRIKHVVPERMAAISKAILARDFDTFARITMQDSNQFHAVALDTDPPIFYMNDVSRAIIALIVEYNRVGKLKAAYTYDAGPNAVIYAPKEIVELIGAVKGLIHTRVGDGPRTLEALLGSD-GLPL Malgl1 ATCTAPVNIAVIK-YWGKRDTKLVLPTNDSLSVTLDQDHLRTVTTAADASFDKLWLNGAEEIKPGGRLDACLCEMRKLRAE-LESLPPLSLRLCSENNFPTAAGLASSASGFAALAVSVAELYGLRSIIARRGSGSACRSVLGGFVAWQMGDGSD--SFAIP--IAEREHWPDLHVLICVVNDAKKGTSSTVGMQNTVETSPLLQHRIKHVVPERMQQMNEAIQKRDFAAFTQLTTADSNNFHACCLDTTPPIFYMNDTSRAIVHVVEELNRAEDPIAAYTFDAGPNAVLYVREKVRQVVGSVRRLIHTRVGDGPRVLESLLSAD-GMPV Mellp23 VTCSAPVNIAVVK-YWGKRDNELILPTNSSLSVTLDQDDLRSTTTALID--DQLWLNGAQVITPGSRLARCLDELRQLRAQ-SEQLPE-SLVIASENNFPTAAGLASSASGFAALAFTVAQLFELQSRIARQGSGSACRSLLGGFVAWDMGDGGD--SGARM--VAPQAHWPDLEAMICVVSDSKKGTSSTGGMAATVATSALLQHRIKDVVPARMAAMEEAIASRDFEKFSALTIADSNQFHAVCLDTTPPIFYLNDVSRAIIAVVEELNRSQGTLATYTFDAGPNAVIYAPRAIVSTIGSISRLICTRVGDGPRVLKGLLTAE-GSTR Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQSTVQTSSLMKHRVLH-VQQRIEQITEAIRLRDFPKFGEITMRDSNEMHAVCLDTYPPIAYLNDTSHQIIRSVHEYNS-GEVRAAYTFDAGPNAVLFCEEKIRDRIGRVSELVECKIGCGPMLR------------ Monbr HTATAPVNIAVIK-YWGKRDTKLLLPINDSLSGTLSQDEMHARTTVASESYDTLWLNNEQTI-SNPRVQNVIRAMRAKAKA------TLPLLICSVNNFPTAAGLASSAAGYAALVAALAGLYDLPTDVARIGSGSACRSLSGGFVRWRRGDGTD--SLASQ--VVPESHWPEMEVLILV-------------------------------------------------------------------------------------LLTKFNA-SSPRAAYTYDAGPNCVIYALKKIIALVDQIKYIIHTGIGDGPRVS--LINEA-GERI Morel2 ATCTAPVNIAVVK-YWGKRDTSLILPTNSSLSVTLSQDQLHSKTSIASADFDRLWLNGIEEIEKNKRLVACLRETRALRAT-LETLPKLAIHICSENNFPTAAGLASSASGYACLVYTLSKLFELPSVVARQGSGSACRSLFGGFVAWEMGDGSD--SRAVQ--IAPETHWPDLQAMICVVSDEKKGTSSTEGMQLTVKTSALLQHRIKDVVPKRMDDMIAAIHAKDFPKFAELTMQDSNQFHAVCLDTYPPIFYMNDISRAIIRIITEYNK-G-VKAAYTFDAGPNAVIYAPKEIFSILGAVKQILHTKADDGPRTLHGLLNAA-GLPK Mucci2 -TCTAPVNIAVIK-YWGKRDTELILPTNSSLSVTLSQDILHSKTTIAAKEYDRLWLNGIEEITKNKRMHNCFRETRAIRQA-MEPIEPLSVHVCSENNFPTAAGLASSASGLAALVYTLSQLFELTSRIARQGSGSACRSLFGGFVAWEMGDGSD--SYAVQ--IAPETHWPDLQALICVVSDAKKGTSSTAGMQSTIKTSLLMNERINNIVPARMEGMKKAVLDKDFQSFAELTMRDSNQFHAVCLDTYPPIFYLNDTSRAIIQLIHEYNATGKLKAAYTYDAGPNAVIYAPKEIIQLIGSVSRLLHTKVDDGPRVLESLLKED-GLPK Mydma VAALAPVNIAVIK-YWGKRSEELNLPLNSSISVTLHSDDLCTKTEILGDGEDIICLNGIEEVSKNPRLKRCLKIVREHSKKFCS------CKIVSTNNFPTGAGLASSASGYACLAKCLGTVYDAYSIIARLGSGSACRSMYGGFVKWQKGDGTD--SIAVQ--VASENHWHGLRVLILVVSSQEKSISSTEGMRRSVKSSPFLQYRVEQCVDERLKLMEEAIQSQNFELFAEITMKESNQLHAVCQDTYPPIIYMNSISHEIVQLITAFND--KIKAAYTFDAGPNAVLFTLEELLATLALIK-IISTKPGPGAHLV------------ Neucr2 ASTTAPVNIAVVK-YWGKRDTKLNLPTNSSLSVTLSQADLRTLTTACSASYDSLLLNGEPSV-SGARPQACFRELRARRAA-LESLPKLSLRIVSENNFPTAAGLASSAAGFAAFVRAIANLYELPSLIARQGSGSACRSLFGGYVAWRMGDGSD--SMADQ--VAEASHWPEMRALILVASAAKKGVSSTSGMQQTVATSSLFKERITSVVPKNMEIMEKAIAERDFAAFAEVTMRDSNSFHATCADTYPPIFYMNDVSRAAIRAVEAINA-GRSVAAYTFDAGPNAVIYYLEQVVGNLNGVSRVIMTSVGEGP--VEYLVAED-GTPV Orpsp11 ATCTAPINIAVIK-YWGKRDTKLNLPTNSSLSVTLSQDDLHTKTTCVSPDLDHLWLNGKEEISQNKRLTNVINEMRAQRKK-MESLPKISLHICSANNFPTAAGLASSAAGFACLTFTLATLYQLKSTIARTGSGSACRSLQGGYVAWEMGDGSD--SHSIQ--VAPREHWPDMQAIILVVNDAKKKTSSTLGMQHTVATSPLIQHRIKYVVPKAMEDMKVAIQNKDFDSFAEITMRDSNSFHAVCADTFPPIYYMNDISRAVVNAIHDYNNAQKYTVAYTFDAGPNAVLYVEKKVLGVINAFKRIIATKVGDGPRILISLLNVN-GEPK Pench1 ATTTAPVNIAVIK-YWGKRDTTLNLPTNSSLSVTLSQRSLRTLTTACSAAYDTLNLNGSPQIQSSKRTMACISNLRALRKA-LESLPKLSLRIVSENNFPTAAGLASSAAGFAALVRAVADLYELPSRIARQGSGSACRSLMGGYVAWRTGDGSD--SLAEE--VAPASHWPEMRALVLVVSAEKKDVPSTEGMQTTVATSALFAERAQNVVPERMAAIETAIKNRNFHDFAEITMRDSNTFHATCLDSWPPIFYMNDVSRAAVRLVHDINR-GRTVCAYTFDAGPNAVIYYEDKVAGTVDGVSRVILTGVGEGP--VEHLVSET-GEIL Phybl2 -TCTAPVNIAVIK-YWGKRDTQLILPTNDSLSVTLSQDILHSKTTIAAKEYDRLWLNGKEEITKNKRMHNCFRETRAIRKA-VEPIELLSVHVCSENNFPTAAGLASSASGLAALVFTLAKLFDLPSRIARQGSGSACRSLFGGFVAWEMGDGSD--SKAVQ--VAPETHWPELEALVCVVSDAKKGTSSTEGMQNTIQTSPLMAERL-KVVPGRMEAMKKAILAKDFESFGELTMRDSNQFHAVCLDTFPPIFYLNDTSRGIMRLIHEYNRSGKIKAAYTYDAGPNAVIYAPKQIIQLIGSVSRLLHTKTHDGPRVLDSLLNEQ-GLPK Picst3 ASSTAPVNIATLK-YWGKRDTLLNLPTNSSISVTLSQNDLRTLTTAASEAFDQLWLNGKLEL-DSVRTQACLADLRRLRAE-VESLPKLSLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYKLPSKIARKGSGSACRSLFGGFVAWEMGNGED--SKAVE--VAPLSHWPTMKAAILVVSDDKKDTPSTSGMQQTVATSDLFQHRITEVVPKRFEEMKRAIAANDFETFGELTMKDSNSFHAVCLDSYPPIFYLNDTSKQIIKLVHRLNE-GKIIAAYTFDAGPNAVIYYDEVVLGLLKGISRIILTSIGTGP--QESLINAD-GTPK Plicr1 ATTSAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLRSTTTSADPSFDTLWLNGKEDIKPGGRLATCISEMKRLRRE-LENEPKLSVHIASYNNFPTAAGLASSAAGFAALVSSLAALYALPSLIARQGSGSACRSLFGGYVAWEQGDGSD--SFAVQ--VAPRSHWPDIHALICVVSDDKKGTSSTSGMQRTVETSELLKHRIAHVVPARMKAISDAILARDFESFARLTMQDSNQFHAVALDTDPPIFYMNDVSRAIIALVTEYNR-GKLKAAYTFDAGPNAVIYAPKEIVRLIGAVKGLIHTQVGDGPRVLEALLGAT-GLPL Polpo ITCTAPVNIATIK-YWGKRDEKLILPLNSSLSGTLHQDDLKTTTTAASENFDAIWLNGKKEI-NTTRYQNVLRMIRSRAT-------KLMVHICSINNFPTAAGLASSASGYACLVYVLAQLYGVSSAIARIGSGSACRSVYGGFVKWEMGDGSD--SIAVQ--VAPETHWPEMNIIVLVVNDKKKETSSTDGMQRSAATSPMMKERCATIVPQRMRDIEAAIQARDFQTFGDITMKDSDDFHEVCATTDPAIYYLNDTSRYIMNLVHKYNK-GKIKCAYTFDAGPNACIYLPEEALALFDSLKYILHTKIGPGPQILSLIDKST-GLPK Pucgr2 ITCSAPVNIAVIK-YWGKRDKKLILPTNSSLSVTLDQHDLRSTTTALLEPSDQLWLNGARQIEKDSRLSNCLKELRKLKAH-FESLPE-SLLIASENNFPTAAGLASSASGFAALVYTISKLYELPSKIARQGSGSACRSIFGGFVSWEMGDGSD--SMAVS--VAERSDWPDLEALICVVSDRKKGTSSTSGMDGSVQTSELLQHRIEKVVPERMKRMKSAIKQKDFDSFAALTMADSNQFHAVCLDTQPPIFYLNDVSRSIIAVIEELNRADGCLAAYTFDAGPNAVIYAPKRLLNLIGSISRLIHTQVGDGPQVLQGLLTVD-GLVK Punst1 ATTSAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLKATTTSADASFDRLWLNGTEEIKEGGRLATCIAEMKRLRRE-VEAEPKISVHISSYNNFPTAAGLASSAAGFAALVSSLAAMYKLPSLIARQGSGSACRSLFGGYVAWEQGDGSD--SYAVE--IAPRGHWPDIHALICVVSDDKKGTSSTSGMQRTVETSELLQHRIKHVVPKRMKDISEAILARDFDAFARLTMQDSNQFHAVALDTYPPIFYMNDVSRAIVAVVTEYNRVGHLKAAYTYDAGPNAVIYAPKEIVQLIGAVKGLIHTRVGDGPRVLEALLGAN-GLPK Rhior3 -TCTAPVNIAVIK-YWGKRDTELILPTNSSLSVTLSQDILHSKTTIAAKEYDRLWLNGKEEITKNRRMHNCFRETRAIRKA-MEPIEPLSLHVCSENNFPTAAGLASSASGLAALVFTLSQLFELTSRIARQGSGSACRSLFGGFVAWEMGDGSD--SLAVQ--VAPESHWPDLEALICVVSDAKKGTSSTAGMQSTIKTSTLMNERINQVVPERMEAMKKAILQKDFQSFAELTMRDSNQFHAVCLDTYPPIFYMNDTSRAIIQLIHEYNASGQLKAAYTYDAGPNAVIYAPKKIIQLIGSVSRLLHTKVDDGPRVLESLLNAE-GLPK Rhoto1 ATCTAPVNIAVVK-YWGKRDTSLILPTNSSLSVTLSQDHLRSLTSACITSGDRLWLNGEEEIKQGGRTERCLSEMRKMRKE-LESLPHIAIHIASENNFPTAAGLASSASGLSALIATLTTLYALTSRIARQGSGSACRSMFGGYVAWEMGDGSD--SVAVE--VAPVEHWPDLHALILVVSDKKKGTPSTAGMQRTVATSALLQHRIKEVVPARMQRITTAIQNRDFDAFAEETMADSNQFHAVCLDTFPPIFYMNDVSRAVIQLVTELNRAEGVKAAYTYDAGPNAVLYVQEKVLELVGAVARIIHTKVGDGPRVLESLLNAE-GMPK Rozal11 ITCQSPVNIAVIK-YWGKENVELNLPTNGSISVTLSMEHIKTITCVSNEQIDSLVLNGELVI--PGRMKLVIDKMRNIAIR-CGPLESPAITIKSRNTFPTAAGLASSASGYSCLVYCLSLLYHLDSEFARLGSGSSCRSLFPGLVEWHLGDSSS-TSVADS--ICDS--WEDLDILVCIVKSEKKKVGSTVGMQQTVKSSALFKHRVEG-MPAKLETMKRAIIAKDFETFANLTMADSNQFHAVCLDTFPPIIYLNEDSRWFIEFVHEYNR-GETAVAYTFDAGPNPVLYMRSKVVRLL-----IIHAKCGAGPSLC--------GI-- Sacce1 ASVTAPVNIATLK-YWGKRDTKLNLPTNSSISVTLSQDDLRTLTSATAPEFDTLWLNGEPHI-DNERTQNCLRDLRQLRKE-MESLPTLSLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPSRIARKGSGSACRSLFGGYVAWEMGDGHD--SMAVQ--IADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMNDTSKRIISWCHTINQ-GETIVAYTFDAGPNAVLYYLAELFAFIKDVARVILTQVGSGP--QESLIDAKTGLPK Salro ATTTAPVNIAVIK-YWGKRDTKLLLPINSSLSGTLDQEQLHARTTVASSSFDEIWLNGKQEI-SNQRLQNVLGAVRALAAK------PLKIKIASVNNFPTAAGLASSAAGYACLVAALAELFGVQTAIARVGSGSACRSLMGGFVRWEKGDGAD--SLASQ--VVPESHWPDMQVLILVVNAGKKGVSSTSGMQSTVKTSALINHRAEVVVPQRMKDIEKAIQDRDFQTFGRITMQDSNQFHATCLDTYPPIFYMNDVSRQIVQILTQYND-GEIRAAYTYDAGPNCVIYCLKQILSLVDGVKYILHTGIGPGPKTLAFLIAED-GSVK Schco3 ATASAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDYLKSTTTSADPSFDQLWLNGTEDIKPGSRLETCIKEMKRLRKVEVESAPKLSVRIASYNNFPTAAGLASSASGFAALVSSLAALYKLPSLIARQGSGSACRSLYGGFVAWEQGDGSD--SLAIQ--IAPESHWPTLHAVVCVVNDAKKGTSSTAGMQRTVETSPLLQHRIKHVVPQRMAEISDAIRARDFDAFARITMQDSNQFHAVALDTDPPIFYMNDVSKAIVALIVEYNRVGKRKAAYTYDAGPNAVIYVEQEIVDLIGGVKGIIHTKIGDGPRTLEALLDAS-GLPK Schpo1 CTVSAPVNIAVIK-YWGKRDVALNLPTNSSISVTLSQDDLRTVTTACSEKFDTLWLNGNAEIFANKRLRVCVEELRKARLD-LEDLDKIGLHVVSENNFPTAAGLASSAAGYAAFCEAIARLYDLPSRIARQGSGSACRSLFGGYVAWEMGSGAD--SVAVQ--VEPVENWPEIRVAVLVASAAKKGVSSTAGMQATVASSTLFQHRIQNIVPQRIQEMKTAIRERDFETFAKLTMTDSNQFHACCLDTFPPIFYLNDTSRAVIRVVENINA-GKTIAAYTFDAGPNAVIYFLEEVLNTLSGISRVILTRVGNGPRVLESLIDAS-GNPK Sorma ASTTAPVNIAVVK-YWGKRDTKLNLPTNSSLSVTLSQADLRTLTTACSASYDSLLLNGEPSV-SGARPQACFRELRTRRAA-LESLPKLSLRIVSENNFPTAAGLASSAAGFAAFVRAIANLYELPSLIARQGSGSACRSLFGGYVAWRMGDGTD--SMADQ--VAEASHWPEMRALILVASAAKKGVSSTSGMQQTVATSGLFQERIKSVVPKNMEIMEKAISERDFAAFAEVTMRDSNSFHATCADTYPPIFYMNDVSRAAIRAVEAINA-GRTVAAYTFDAGPNAVIYYLEQVVGNLNGVSRVIMTSVGEGP--VEYLVAED-GTPV Sphar ATCSAPVNIAVIK-YWGKRDEKLILPTNSSLSATLDQADLKTTTSVLSSEFDRLWLNGKEEI-TNPRLQNVLQKIRSLASE---EEKAVLVHIVSVNNFPTAAGLASSASGYACMVYTLAQVYGVTSKIARVGSGSACRSMYGGWVAWNMGDGDD--SFAEQ--THLADHWPGMKILILVVSDRKKGTSSTSGMGTSVRTSELLQHRITEVVPKRMAAIKEAIEARDFAQFGEITMRDSNQFHAVCLDTYPPIFYMNDTSKAVVQMVTQYNT-GEVKAAYTFDAGPNAVIYAMEDIASLTDSLQYGINTQPGPGPQVLECLLDSS-GLPK Spipu1 VTVSAPVNIAVVK-YWGKRDTSLLLPTNSSLSLTLSQDDLRSTTTVADPSFDRLWLNGKEEVTKNKRMVNVVRELRALRQR-MESLEKLSLHVCSQNNFPTAAGLASSASGFAALTFGIAHAIGV-SRLARLGSGSACRSLFGGFVAWEMGDGVD--SVAVQ--VADESHWPDMEALVLVASDARKDTPSTAGMQLTVETSELLQERIRQ-VPQRMQDMKQAIANKDYDAFAELTMMDSNQFHAVCLDTFPPITYLNDVSRAVIHLITAYNALKGYRAAYTFDAGPNAVLYILKEVLALVGSLRRIISTSVGDGPRILVSLLGED-GLPK Sporo1 ATCTAPVNIAVVK-YWGKRDTSLILPTNSSLSVTLSQDDLRSLTTAAIPD-DRLWLNGEEEIKHGGRTQRCLEELRKLRKH-YESLDPLSLHIASENNFPTAAGLASSASGLSALIQTISTLYCL-SRIARQGSGSACRSMFGGYVGWEMGDGSD--SVAYE--VAPVEHWDDLNAIILVVSDKKKGTPSTAGMQRTVATSSLLQHRIKDVVPKRMAKIERAIKEKNFDTFAKETIEDSNQFHAVCLDTTPPIFYLNDVSRSIIQLVEELNRSGRLVAAYTYDAGPNAVLYVQQKVLSTVGAVSRIIHTKVGDGPRVLEGLLNSE-GLPK Stehi1 ATVSAPVNIACIK-YWGKRDTKLILPTNSSLSVTLDQDHLRATTTSADPSFDRLWLNGKEEIEAGGRLATCITEMKALRRQ-VEKEPKLSVHIASRNNFPTAAGLASSAAGFAALVASLAALYQLPSIIARQGSGSACRSLFGGYVAWEMGDGSD--SRAVE--IAPREHWPEMHALICVVSDVKKGTSSTSGMQRTVATSPLLQHRIKHVVPARMAGISKAILEKDFDTFATLTMQDSNQFHAVALDTDPPIFYMNDVSRSIIALITEYNRVGKIKAAYTYDAGPNAVIYAPQEIIELIGAVKGLIHTRVGDGPRKLETLLGAE-GIPT Tapde11 SSTTAPVNIAVVK-YWGKRDPTLNLPTNSSISVTLSQDDLRAWTTACSQDFDRMWLNGEERTTDDKRLLACLKELRSLRTR-VETLPKLSLHIASENNFPTAAGLASSAAGFAALVRAVADLYKLPSRIARQGSGSACRSLFGGYVAWEMGDGSD--SQAVQ--VAEADHWPTMKACILVASAQKKDVSSTSGMQSTTKTSLLFRERIERVVPDRMARMTEAIRARDFSTFAELTMRDSNGFHAVCLDTYPPIFYMNDVSRAVVRLVEHING-GETVCAYTYDAGPNTVIYYLREVLSFVAGVSRVILTKIGGGP--ERSVLGPD-GFPR Thetr ATTTAPVNIAVIK-YWGKRDVGLMLPLNSSLSGTLNQDDMASKTSVASLDLDELWLNGVKEIAGNKRVQTVIQLAREHASDVYDVVIKAALLIVSENNFPTAAGLASSASGYACLTYALAQVLNVESAIARRGSGSASRSMYGGWVKWVEGDGTD--SIAVQ--VAPHTHWPSMRVLVLVANDQKKHVSSSKGMQLTAATSPLIPDRLA-MLPGRMAAMEKAILERDYATFADLTMKDSDNFHATCATTEPPIHYMTDVSRDVVKVVNAYNT-GSLAAAYTFDAGPNAVIYLEDDFLSAVGRLKYLLYTSVGDGPRVLECLIDVEAGRPK Treme1 ATISAPVNIACIN-H-----------------------DLRSTTTACDPIFDKLWLNGKEEVKFGGRTATCIEVLRGWRRD-LELEP-LSLRVASHNNFPTAAGLASSASGLAALVFSLATLYSLPSLVARQGSGSACRSLFGGYVAWREGDGSD--SIAEE--IAPRDHWPEMCALICVVSDAKKGTSSTSGMQRTVETSTLLQHRLT-IVPERMTAISHAIKERNFDSFAQITMTDSNSFHAVCLDTSPPIFYMNDVSRSIIAMVEELNRVYGRIAAYTFDAGPNAVIYALEKVEKSVGAVKSLIKTRVGDGPRVLESLL-KD-GQLK Trire2 ASTTAPVNIAVVK-YWGKRDAKLNLPTNSSLSVTLSQNDLRTLTTACSPSYDSLLLNGEPSI-SGARTQACFRELRARRAA-LESLPKLSLRIVSENNFPTAAGLASSAAGFAALVQAIANLYELPSLIARQGSGSACRSLFGGYVAWRMGDGSD--SMADL--VAPASHWPSMRALILVVSAAKKGVSSTSGMQQTVATSGLFKERIATVVPANMALMEDAIKNRNFPQFAEVTMRDSNSFHATCADTYPPIFYMNDVSKAAIRAVEAINA-GKTVAAYTFDAGPNCVVYYQEEVLGAFEGVSRVIMTGVGEGP--QEFLVAED-GTPV Umbra1 -TCTAPVNIAVIK-YWGKRDTGLILPTNDSLSVTLSQDILHSKTTIAAKEYDRLWLNGKEEITKNKRMHNCFRETRALRQQ-METLEPLSVHVCSENNFPTAAGLASSASGLAALVFTLAKLFDLPSRIARQGSGSACRSLFGGFVAWEMGDGSD--SLAVQ--VAPETHWPELEALICVVSDEKKGTSSTEGMQHTVNTSPLLQHRIKEVVPARMAEMKKAIHNRDFQTFAELTMQDSNQFHAVCLDTYPPIFYLNDTSRAIMKIIHEYNATGKLKAAYTYDAGPNAVIYAPKEIIQLIGSVSRLLHTKTDDGPRVLESLLNEQ-GLPK Ustma22 ATCSAPVNIAVIK-YWGKKDTTLILPTNDSLSVTLDQDHLRSVTTAADASFDRLWLNGEEEIKADGRLRRCIDEMRKLRQA-KENLAKLSVHVCSENNFPTAAGLASSASGFAALIASLAALYELQSRIARQGSGSACRSLFGGYVAWQGGSGQD--SLAVQ--VAPQSHWPDLQALICVVSDAKKGTPSTAGMQRTVQTSPLLQHRIKEVVPQRMIKISEAIQKQDFNTFAEITMADSNNFHACCLDTAPPIFYMNDVSRAIVQLVEELNRAKGKLVAYTYDAGPNAVLYAPKDILQTIGAVRRLIHTQVGDGPRVLESLLNEN-GEPI Walse1 ITVTAPVNIAVIK-YWGKRDVKLNLPTNSSLSVTLSQDEMCSKTTVVDKSYDTLVLNGEENI--NGRLVNVLNVMRESTTE-SE------VRIESTNNFPTAAGLASSASGFAALVYGLGKIF-VPSTIARQGSGSACRSLFGGFVAWNKGDGSD--SSAVE--IAPQSHWDDLDALICVVSANKKAVASTAGMQRTVETSPYLQHRADNVVPKRMDDIIDAIKSKDFDKFADITMMDSNSFHASCLDTHPPIFYLTDVSRAIINVVHALNN-GRHVAAYTFDAGPNAVLYVQRKVLSIINGLSRIIQTSIGDGPRIV------------ Zygro1 ASTTAPVNIATLK-YWGKRDKALNLPTNSSISVTLSQEDLRTLTSATGPELDKLWLNGKEEL-ESERTQQCLKGLRKLRKE-LENLPKFSLHIVSENNFPTAAGLASSAAGFAALVVAIARLYQLPSEIARQGSGSACRSLFGGYVAWEMGDGSD--SKAVE--ISPLEHWPQMKAAILVVNASKKDTPSTSGMQLTVKTSELFQERVKNVVPQRFTHMKEAIEHKNWPKFAELTMKDSNSFHATCLDSYPPIFYMNDTSKKIIKLCHAINE-GKTVVAYTFDAGPNAVLYYLQELFAFINGVSRVILTQVGPGP--LESLIDENTGLPK [Cluster1374.fasta_al_trimmed; alignment length = 78] Allma1 MQNDKGDIV--DLYIPRKCSATGRLITAKDHSSVQINIADVDTFAFSGAVRRAGESDDSLNRLAQQSGYLKNVWSAIH Ashgo11 MENDKGQLV--ELYVPRKCSATNRIIKAKDHGSVQINIAQVDTYALSGYVRARGEADDSMNRLAQKDGLLKNVWSYSR Aspfu1 MENEKGEIV--DLYVPRKCSATNRIIKANDHASVQISIAKVDSYALCGFIRARGESDDSLNRLCQRDGYIRNVWSASR Aurde31 MENDQGVLV--DLYVPRKCAATNRLITSKDHASVQISIADVDSFALCGQVRAMGESDDSLNRLATKAGLLRNVWSYQK Batde5 --------V--DLYIPRKCSATGRLIAAKDHAAVQINIGDVDTYAFSGFVRAAGESDDSLNRLATLDGYLKNVWSYSK Botbo1 MENDQGALV--DLYVPRKCAATGRLITSKDHASVQIMIADVDTFALCGQVRAMGESDDSINRLATRSGLLRNVWSYAK Botci1 MENDKGELV--DLYVPRKCSATNRIIKAKDHGSVQISIAKVDVYALCGFIRAMGESDDSLNRLAQRDGLLKNVWSGQS Caeel MQNDAGQTV--ELYVPRKCSSSNRIIGPKDHASVQIDFVDVDRYAICGAIRRMGESDDAILRLAQKDGLVPRDDVKSN Canalb1 MENDKGQLV--ELYVPRKCSATNRIIKAKDHASVQISIAKVDTYALSGYVRGRGEADDSLNRLAQQDGLLKNVWSYSR Cangl MENDKGQLV--ELYIPRKCSATNRIIKADDHASVQINIAKVDTYALSGNVRARGESDDSLNRLAQNDGLLKNVWSYSR Capow MDG--------NLYTPRMCSATGRIIQAKDHASVQISVGDVDHYALSGFVRAQGEADDSINRLAQKDGALHKVFEGFQ Catan2 ------------------------------------------------------------------------------ Cioin MQNDAGEVV--DLYIPRKCSASGRIIGAKDHASVQLSFIDVD-YTICGDIRRMGESDDCLNRLAKKDGIMS------- CocheC53 MENERGELV--DLYVPRKCSATGRIIRAKDHASVQLSIGKVDVYAISGFVRAMGESDDSLNRLTQKDGFLKSVWSASR Coere1 MENDRGDIV--DLYIPRKCSATGRLIGAKDHAAIQINIAEVNTYAISGLVRGRAESDDSLNRLASNDGYLKNVWDYQR Conco1 MENSEGQIV--DLYIPRKCSATNRLITAKDHSSVQIVIPNVDTYALSGFVRAQGEADDSLNRLATEDGYLKNTYSSRR Conpu1 MENDQGVLV--DLYVPRKCAATNRLITSKDHASVQINVADVDSFALCGQVRSQGESDDSINRLATKAGLLRNVWSYQK Copci ------------------------------------------------------------------------------ Croqu1 MENDQGIVV--DLYVPRKCAATNRLITAKDHSSVQINVAEVDTYALSGFVRREAEADDSINRLATQDGLLRSVWSPAR CryneH991 MENDKGVLV--DLYIPRHCSATNRLITAQDHASIQLQIADVDTIAICGRIRAQGDSDDSINRIATKEGLLKNVWSYTR Crypa2 MENDRGEIV--DLYVPRKCSATNRIIKAKDHASVQISVAKVDTYALCGFVRAMGESDDAFNRLAQRDGLVKNVWSAQR Debha1 MENDKGQLV--ELYVPRKCSATNRIMKAKDHSSVQINIANVDTYALCGYIRGRGEADDSLNRLAQQDGLLKNVWSYSR Dekbr2 MENDKGDLV--ELYIPRKCSATNRIIKSGDHASVQINVANVDTYALCGYVRARGEADDCLNRLAQQDGIINNVWSYSR Dicdi ---MDSKNV--ELYTPRKCSATNRLITAKDHASVQINIGHVNIFAFCGFLRNNGQSDAALNRLAQQKGFLKSF----- Dmel MENDAGENV--DLYVPRKCSASNRIIHAKDHASVQLSIVDVD-YAICGEIRRMGESDDCIVRLAKKDGIITKNF---- Enthi MASNKK----IELYIPRHCSVTHTLIAADDHAAVQILVPHVNVYTVKGSVRKDGISDHSLNRQFQKDGFLKTVVPKNM Falba --------M--D-FIPRKCSVTGRLLTIKDHASVQINVGEVDTYAVSGYVRANAESDDSITRLAKEDGLLQESFTA-- Fomme1 MENDQGVLV--DLYVPRKCAATNRLITSKDHASVQISIVDVDTFALCGKVRASAESDDSINRLATQAGLLRGVWSYQK Fusgr1 MENDRGEIV--DLYVPRKCSATNRIIKAKDHGSVQISIAKVDVYALCGFVRAMGESDDSLNRLAQRDGLLKSVWSGQR Galma1 ------------------------------------------------------------------------------ Ganpr1 MENDKGEIV--DLYIPRKCSATGRLITAKDHASVQINVGEVDTYAMSGFVRAAGESDDSLNRLATKDGFLKR------ Gloin1 MQNDQGIQV--DLYKPRKCSATNRLITAKDHASVQINVGDVDRYELCGFIRSSGESDDSLNRLATSDGYLKSVWSSQR Hisca1 MENEQGKIV--DLYVPRKCSATNRIIKAKDHASVQISIAKVDVYALCGFVRARGESDDSLNRLAQRDGFLKNVWSASS Klula1 MENDKGQLV--ELYVPRKCSATNRIIKAKDHSSVQINIAQVDTYALSGYIRARGEADDSLNRLAQQDGLLKNVWSYSR Lacbi2 MENDSGILV--DLYVPRKCAATNRLITSKDHASVQLSIVDVDTFALCGQVRSQGESDDSINRLATKAGLLRNVWSYQK Lenti61 MENDQGILV--DLYVPRKCAATNRLITSKDHASVQISVADVDTFALCGQVRAMGESDDSLNRLATKAGLLRNVWSYQK Malgl1 MENDHGELV--DLYVPRKCAASGRLIEAKDHSSVQIAVCDVDNIPISGAIRHHGESDDSLNRIAQQMGCM--YFSAL- Mellp23 MENDQGIVV--DLYVPRKCAATNRLITAKDHSSVQINIAEVDTYALSGFVRREGEADDSINRLATRDGLLKNVWSASK Mnele MQNDKGEIV--DLYIPRKCSITNRIISAKDHASVQINIGELDTFASCGFVREMGEADDSFNKLCSDAKILQF------ Monbr MQNDHGEVV--DIYLPRKCSATNNIIGATDHAAVQINVAKVDSYAICGPVRSMGETDDSLNRLTDRDGITKNTPRKLR Morel2 -METPQITL--ETYVPRKCSATNRLIGAKDHASVQINIGGVDTYALSGYVRAQSEADDSINRLATKDGLLSMVWNYQK Mucci2 MENSEGQVI--DLYIPRKCSATNRLITAKDHASVQINVADVDTYAFCGFLRKEAESDDALNRLSQQDGYLKNVFSYQQ Mydma MQNDAGEVV--DIYIPRKCSATNNIISAKDHASVQISIAEVD-FAFCGKVRSAGESDDALINLCMKDGIISKNY---N Neucr2 MENDRGEIV--DLYVPRKCSATGRIIKSKDHGSCQITIAKVDIYALSGFVRAMGESDDSLNRLAQRDGLLKAVWNPQR Orpsp11 ------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------ Phybl2 MENSEGKFV--DLYVPRKCSATNRLITAKDHASIQLNVAEVNTYALCGFVRKNAEADDSLNRLATQDGFLKNVWSYQQ Picst3 MENDKGQLV--ELYVPRKCSATNRIIKAKDHASVQINIANVDTYALSGYVRGRGEADDSLNRLAQQDGLLKNVWSYSR Plicr1 MENDQGVLV--DLYVPRKCAATNRLITSKDHASVQISVVDVDTFALSGKVRADGESDDSINRLATKEGLLRNVWSYQK Polpo MQNEDKKNI--ELYTPRKCSATNRLITAKDHASVQINIGHVNSVAFCGFIRNNAQSDAALNRIAQKKGFLKSF----- Pucgr2 MENDQGIVV--DLYVPRKCAATNRLITAKDHSSVQINVAEVDTYALSGFVRREGEADDSINRLATQDGLLRSVWSGSR Punst1 ------------------------------------------------------------------------------ Rhior3 MENSEGQLI--DLYIPRKCSATNRLITAKDHASVQINVADVNTYAFCGFVRKEAESDDSLNRLAQQDGYLKNVFSYQQ Rhoto1 MQNDQGQVV--DLYVPRKCSATNRLIIAKDHASVQINVAEVDTYAFCGSVRETGDADESLNRLATQDGLLKNVFQYAQ Rozal11 MQNSEERIVIGDLYTPHN-DATNRLITPKDHASIQLNVVDVDTYALSGFVRALGESDDCINRLATRDGYLKNVWSYQK Sacce1 MENDKGQLV--ELYVPRKCSATNRIIKADDHASVQINVAKVDTYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR Salro MQNLEGRLV--DLYIPRKCSATNNLIGASDHASIQVDIAKVDSYVFCGEVRAQGETDDSLNRLATQDGILKNVYEKN- Schco3 MENDQGVLV--DLYVPRKCSATNRLITSKDHASVQINVADVDTFAFSGQVRAMGESDDSLNRLATKAGLLRNVWSYQK Schpo1 MENEAGQLV--DLYVPRKCSATNRIIQAKDHASVQINVCAVDTYAISGFVRSKGESDDCINRLTTQDGLLEGVWSYQR Sorma MENDRGEIV--DLYVPRKCSATGRIIKSKDHGSCQITIAKVDIYALSGFVRAMGESDDSLNRLAQRDGLLKAVWNPQR Sphar MQNDKGVIV--DMYIPRKCSATNRIIGAKDHASVQVNIADVDTYALSGFVRALGESDSSIVRLGEADSLVTTM----- Spipu1 MENEKGQIV--DLYIPRKCSATGRLITAKDHASVQINVGDVDTYALSGFVRSMGESDDSVNRLATADGYLKGVWSYQQ Sporo1 MQNDQGQVV--DLYVPRKCSATNRLIIAKDHASVQINVAEVDTYAFCGTLREKGDSDDSLNRLATSDGLLKNTWSYAQ Stehi1 -----GILV--DLYVPRKCAATNRLITSKDHASVQISVVDVDSFALCGQVRADGESDDSINRLATKAGLLRNVFSYQK Tapde11 MENNEGKLV--DLYVPRKCAATNRLIKAHDHASVQLNICDVDTFALCGFVREKGESDDCINKLATQAGLLKNVWSYSR Thetr ------------------------------------------------------------------------------ Treme1 MENDKGVLV--DLYIPRHCSATNRLVTAKDHAAIQISVADVNTIVICGRIRAQGDSDDSINRIATKDGLLKNVWSYSR Trire2 MENDRGEIV--DLYVPRKCSATNRIIKAKDHGSVQISIAKVDVYALCGFIRAMGESDDSLNRLAQRDGLVKSVWSAQR Umbra1 MENSEGRLV--DLYIPRKCSATNRLITAKDHASVQINVGDVDTYALSGFVRKESEADDSINRLATKDGLLKNVWSYQK Ustma22 MENDRGDLV--DLYVPRKCAATGRIIEAKDHASVQIAVADVDNFPLSGFVRQLGEGDDSLNRLAQKEGLLRNVWSYQK Walse1 MENDKGELV--DLYVPRKCHATGRLITPKDHTSVQLSVAQVDFIALSGDVRAMGEADDSINRLATERGLLRNVFTYAK Zygro1 MENDKGQLV--ELYVPRKCSATNRIIKAKDHGSVQINIAKVDTYALCGYVRARGEGDDSLNRLAQNDGLLKNVWSYSR [Cluster1406.fasta_al_trimmed; alignment length = 153] Allma1 MRPLTEDETKTFFEKLAKYIGKNITQLIDFRLHKDRVYYVLIALGACFGKF-TKSGQFRLAITALDHLAQYAKK-VWVKPNGEMPFLYGNHVLKAHLGRISDDTPEHTGVVVFNMSDIPLGFGVTAKSTSETRKMDPTAIVAYHQADVGEYIR Ashgo11 MRQLTEEETKVVFEKLAGYIGRNISYLVDFRLQKDRVYYMLMSLGICLGKF-TKTGKFRLHITALTVLAQHAKK-VWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHSGVIVFSMHDVPLGFGVSAKSTSEARDLQPMGIVAFRQADIGEYLR Aspfu1 MRQLTEQELQTLLAKLAGYTGRSLNNLIVFRLQGNRVYYVLLSLGTCIGKF-TKTGKFRIHITALDVIAPHARK-VWIKDNGIMPYLYGSNVVKAHVGRWSEDIPEHTGVLVYDSNDTPLGFGVTARSTAEIRKLDPTAIAVFRQADIGEYLR Aurde31 MRPLTEEESTAVFQKLANYIGKNVVHLVDFRLHRDRVFYVLVSLGTCFGKF-SKSGKFKLHITALDYLAQYAKK-VWVKPNGEMPFLYGNHVLKAHLGRITEDTPEHQGVVVYSMSDVPLGFGVTARSTVDTRKLDPTAILVFHQADVGEYLR Batde5 MRPLTEEETKTFFEKLAKYIGRNIAHLIDFRIQKDKVYYVLLALGVCFGKF-TKTGKFRLHVTALDYLAQFAKK-VWVKPNGEMSYMYGNHVLKAHLGRITEDTPEHQGVIVYTMADVPLGFGVTAKSTGDCRKMDPTSICVFHQTDIGEYLR Botbo1 MRPLTEDESKAVFSKLANYIGKNLIHLIDFRLHRDRVFYVLVSLGTCFGKF-SKSGKFKLHITALDYLAQYAKK-VWIKPNGEMPYLYGNHVVKAHLGRITEDTPEHQGVVVYNMSDVPLGFGVTARSTIDTRKLDPTSIIVFHQADVGEYLR Botci1 MRPLTEPETQTLFAKLAGYTGNSLKNLIAFRVQQSRCYYVLLSLGICLGKF-TKSGKFRIHITALPILAEHARK-VWVKANGEMPFLYGGHIVKAHVGRWSEDCPEHQGVVVYSMNDTPLGFGVTARSTQEARRLDPTGIVCFRQADAGEYLR Caeel MRPLTEEETSLVFAKLASFIGDNVSMLIDFRNHKERVYYCLLSFGTCLGKF-TKSKKFHLQITALDYLAPYAKK-VWLKPNAEQQFLYGNNILKSGIARMTDGTPTHAGIVVYSMTDVPLGFGVSAKGTSDSKRADPTALVVLHQCDLGEYLR Canalb1 MRPLTEEETKVVFEKLANYIGRNISFLIDFRLQKDRVYYVLMSLGTCFGKF-TKTGKFRLHITSLPYLAQYAKK-IWIKQNGEMPFLYGNHVLKAHIGRMSDDIPEHAGVIIYSMNDIPLGFGASAKSTAEARNLPPTGIVAFRQGDIGEYLR Cangl MRQLTEEETKVVFEKLAGYIGRNIAYLVDFRLQKDRVYYVLMSVGICLGKF-TKTGKFRLHITALSVLAKHAKK-IWIKPNGEMPFLYGNHVLKAHVGKMTDDIPEHAGLIVFSMNDMPLGFGVSAKSTLESKNLQPTAIVAFRQADIGEYLR Capow MRPLTEDETKIFFEKLANYIGGNIQLLIDFRLHRDRVYYVLMSLGTCFGKF-TKSGKFRLQVTALEFLAPYAKK-VWVKPNAEQSYLYGNHVLKSGLGRITEDTPRYQGVVVYSMNDIPLGFGVAAYSTQDCRKLDPTGYHCFPPSRC----R Catan2 MRPLTEEETKTFFEKLAKYIGKNITLLIEFRLHKDRVYYVMCALGTCFGKF-TKSGLFRLHVTCLDILAKYAKK-VWVKPNGEMPYLYGNHVLKAHLGRISDDTPEHTGVVIYNMNDVPLGFGVTAKSTSETRKMDPTAIVAYHQADVGEYIR Cioin MRPLTDEETKIMFEKLAKYIGEGIKDLIDFRLHKERVYYVLISLGVCFGKF-TKTRKFRLHVTALDYLAPYSKK-VWVKPSAEQTFLYGNHIMKAGLGRITDNTPKYQGVVVYSMADVPLGFGVAAKSTAECRKSDPMTIIAFHQADVGEYLR CocheC53 MRPLTEPETKTLFEKLASYCGKGITNLIAFRVQGSRVYYVLLSLGICLGKF-TKTGKFRLHITALSVIAPHARK-VWVKQNGEMPFLYGGNVLKAHVGRWSEDCPEHQGVVVLSMNDTPLGFGVSARSTADARKLDPTGIVTFRQADIGEYLR Coere1 MRPLTDDETKVLFEKLAKYIARNIIHLIDFRLQKDRVYYVLVSLGICFGKF-TKTGKFRLHITALQYLAQYAKK-VWIKPNGEMPFLYGNHVVKAHIGRVTEDIPEHQGVVIYNMADVPLGFGVSARSTVDMRKVDPTGIAVFHQADNGEYLR Conco1 MRPLTEEETKTFFQKLSTYIGKNLVQLVDFRLHNDRVYYMLLSVGVCFGKF-TKTRKFRLQITCLDYLAKYAVK-LWIKPNGEMPYLYGNHVVKAHLGRITDDTPEHQGVVIFSMSDTPLGFGVLAKSSNDIKKMDPNSIIAFHQSDIGEYLR Conpu1 MRPLTEEESKAVFEKLANYIGKNLIHLIDFRLQKDRVYYVLISLGTCFGKF-SKSGKFKLHITALDYIAQYAKK-VWIKPNGEMPFLYGNHVVKAHVGRLTEDTPEHQGVVVFSMSDIPLGFGVTARSTIDSRKLDPTAIVVFHQADVGEYLR Copci MRPLTEDESKAVFTKLANYIGKNLVHLIDFRLHKDRVYYVLVSLGTCFGKF-SKSGKFKLHITALDYLAQYAKK-VWIKPNGEMPFLYGNHVLKAHLGRITEDTPEHQGVVVFSMNDIPLGFGVTARSTIDTRKLDPTSIIVFHQADVGEYLR Croqu1 MRPLTDTEVKTLFSKLHNYVGKNLVHLIEFRLHRDRVFYVLISLGTCLGKF-SKTGKFKLHVTALDWLAKFAQK-VWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVIFSMSDVPLGFGVTARSTTDTKKLDPTSIIVFHQADVGEYLR CryneH991 MRPLTEEETKAVFEKLANYIGKNLVHLIDFRLHKDRVYYLLVSLGTCFGKF-SKTGKFKLGITCLDYLAKYAKK-VWIKPSGELPFLYGNHVAKAHLGRITEDTPEHQGVVVYNMSDVPLGFGVTARSTLDTRKLDPTGIIVFHQADVGEFLR Crypa2 MRPLTEPETQTLFQKLAHYTGNSLKNLIAFRVHKDRVYYVLTSLGICLGKF-TKTGKFRLHITSLPILAEHARK-IWVKPNGEMPFLYGGNIVKAHVGRWSDDCPEHQGVIVYSMNDTPLGFGITARGTSEARRLDPTGVVAFRQADCGEYLR Debha1 MRSLTEEETKIVFEKLANYIGRNISFLIDFRLQKDRVYYVLMSIGTCFGKF-TKTGKFRLHITALPYLAQYAKK-VWIKTNGEMPFLYGNHVLKAHIGRMSDDIPEHAGVIVYSMNDVPLGFGVSAKSTNEARALQPTGIVAFRQGDIGEYLR Dekbr2 MRQMTEEETKVVFEKLANYIGRNITFMVNFRLQKDRVYYVLISLGICLGKF-TKHGKFKLHITALPYLAKYAKK-VWIKENGEMPFLYGNHVLKAHVGKMSEDIPEHAGVIVFSMKDIPLGFGVSSKSTLEAKNLTPTGIVALRQADIGEYLR Dicdi MRPMTEEESKTFFEKLIKFIGKNVTLLIQFRIQKNKVYYVLCSLGTCFGRF-TKTGKFKLNITCLDYLAQYAKK-VWVKPSSEMSWMYGNNLLKAGLGRITEDTPANQGVVLFSMNDVPIGFGVTSKSTHECRKLDPQALVVYHYGDVGEYLR Dmel MKRLSDERAKILFEHLSKYIGTNVKHLIDFREHKDRVYYVLVCVGTCFGKF-SKTNKLKFHITALYYLAPYAQK-VWVKPSFEQQFLYGNHIPKTGLGRITENAGQYQGVVVYSMNDLPLGFGVLARSTTDCKTADPMTTVCFHQSDIGEYIR Enthi -------------------------------------------------------------------------------------------------------MARNIGCVMFNENDIANGFGTTACSSVEYSRISATGIVCYNQGELGEYLR Falba MRPLTDEETRVFFEKLMNYIGDNISFLVEFRLVKDRVYYMLLALGTCFGKF-TKTGKFRLHVTALDYLAQYAKK-VWIKPNGEMSFLYGNHIAKAHVGRLTDDIPMYAGVVVFNMADVPLGFGVAAQTTEAARKLDPTAIMAFHQADVGEYLR Fomme1 MRPLTEDESKLVFTKLANYIGKNLVHLIDFRLHKDRVFYVLVSLGTCFGKF-SKSGKFKLHITSLDFLAQYAKK-VWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVVYSMNDTPLGFGVTARSTADVRQLDPTAILVFHQADVGEYLR Fusgr1 MRPLTEKETQTLFEKLANYTGGSLKNLIAFRLVRDRVFYVLLSLGTCLGKF-TKTGKFRLHVTALPIIAEHARK-IWVKENGTMPFLYGSNIVKAHVGRWSEDCPEHQGVVVYSMNDTPLGFGVTARSTAEARRLDPTGITCFRQADCGEYLR Galma1 MRPLTEDESKAIFTKLANYVGKNLVHLIDFRLHKDRVFYVLVSLGTCFGKF-SKSGKFKLHITALDYVAQYAKK-IWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVVFSMSDIPLGFGVTARSTVDTRKLDPTAIIVFHQADVGEYLR Ganpr1 MRPLIDDETKVFFEKLAKYIGKNIAMLIDFRLQKDR----LVSLGTCFGKF-TKSGHFRLHVTALDIIAPYAKK-VW-------------------------------------------GFGLASRTITAMRALDPTGICMLHQADVGEYLR Gloin1 ---------------------------------------MLISLGVCFGKF-TKSKKFKLHITALDYLAQYAKK-IWIKPNGENTFLYGNHILKAHLGRITDDTPEHQGVVVYSMSDIPLGFGVTARSTVETRKLQPTDIVAFHQADIGEYLR Hisca1 MRALTETETKTLFSKLANYTGRSLNNLIAFRLHGSRVYYVLLSLGTCIGKF-TKTGKFRLHITALDVIAPHARK-VWIKPNGEMPFLYGGNIVKAHVGRWSEDCPEHSGVVVYSMDDTPLGFGVTARSTAEARRLDSTSIATFRQADIGEYLR Klula1 MRQLTEEETKVIFEKLAGYIGRNIVYLVDFRLQKDRVYYVLMSLGLCMGKF-TKTGKFRLHITSLSVLAQYAKK-VWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFSMHDVPLGFGVSAKSTSESRDLQPTSIVAFRQADIGEYLR Lacbi2 MRPLTEDESKAIFTKLANYIGKNLVHLIDFRLQKDRVYYVLVSLGTCFGKF-SKSGKFKLHITALDYIAQYAKK-VWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVIFSMNDIPLGFGVTARSTTDTRKLDPTSIIVFHQADVGEYLR Lenti61 MRPLTEEESKAVFTKLANYVGKNLVHLIDFRLQKDRVFYVLVSLGTCFGKF-SKSGKFKLHITALDYLAQYAKK-VWIKPNGEMPFLYGNHVLKAHLGRITEDTPEHQGVVVFSMNDIPLGFGVTARSTVDTRKLDPTAIIVFHQADVGEYLR Malgl1 MRPLTDAETTTLFEKLAHYIGKNLVHLIDFRLHRDRVYYVLMSLGTCFGKF-SKTGKFRLHITALDYLVQYARK-VWIKPNGEMPFLYGNHVLKAHVGRITDDTPEHAGVVVLSMSGVGLGFGVTARSTSDTRNMDPTNIIVFHQADVGEYLR Mellp23 -----------------------------------------------------------------------------------MPFLYGNHVVKAHLGRITEDTPEHQGVVVFSMSDVPLGFGVTARSTTDTKKLDPTSIIVFHQADVGEYLR Mnele MRPLTEEEAKSLFEKLAKYIGENMKLLLEFRYHKDKVYYVLISLGTMFGKF-SKGGKFKLHITCLDFLSSYAKK-VWLKPGAEQQFLYGNNVTKAGLGRISAGTEKYDGVVVYNMADLPLGFGVAAKSTVACKTTEPNTIVVFHQADVGEYVR Monbr MRPLTEEETTIFFEKLTKYIGANVKLLIDFRLHRDRVFYVLISLGTCFGKFTKKSNQFKLHVTALTYLAPYAQK-VWVKQSSEQSFLYGNHVLKSGLARMTENTPQHQGVVVYNINNIPLGFGATSKSTQECRTLDPAAIVIYRQADVGEYLR Morel2 MRPLTELETKTFFEKLAKYIGRNITHLIDFRLHRDRVYYVLISLGICFGKF-TKTGKFRMHVTCLDYIAQYAKK-VWIKPNGEMPFLYGNHVVKAHIGRVTEDTPEHQGVIVYSMTDVPLGFGVTARSTSDTRKMEPTAIVVFHQADIGEYLR Mucci2 MRPLTAEETTTLFEKLAKYVGANLKHLIDFRLQKNKVYYLLGSVGVCFGKF-TKTGKFKLHITALDHLAQYAKK-IWIKPNGEMPFLYGNHIVKAHLGRITDDTPEHTGVIIFSMTDSPLGFGVTARSTMDMKKLQPTDIIVFHQADVGEYLR Mydma MRPLTEDETKSVFEKLTKYIGENVKCLIDFRLHKDRIYYVLASMGTCFGKF-TKSGVFKLQITALDFLAPYAKK-VWVKPGSEQSFLYGNHVQKGGLGRITDNTPQYQGVVVYSMSDCPLGFGAVAKSTQQCRHADSSDIVCFHQADIGEYLR Neucr2 MRPLTETEQKTVFEKLANYC-TDLKSLIAFRLNHSRVYYVLLSLGTCLGKM-TKTGKFRLHITALPILSEHARK-IWVKDNGAQPFLYGSNVVKAHVGRWSEDCPEHSGVVVYSMADIPLGFGVTARSTTEARRLDPTGIVCFRQSDCGEYLR Orpsp11 ----------------------------------------LLSLGVCFGKF-TKTGKFRLHITALDYLAQYAKK-IWVKPNGEMPFMYGNHVLKAHLGRITEDTPEHQGAIIYSMNDIPLGFGVTARSTSDCRKLDPTGIVVFHQADIGEYLR Pench1 MRSLTEEETRTLFTKLASYTGRSLNSLITFRLQGCRVYYVLLSAGTMVGKF-TKTGKFRINLTALDLLAQNARK-VWIKANGVMPLLYGGSVLKAHVARFSEDCPENAGVVILDSNDVPLGFGVTARSSAQIAKLDPTSIAVHRQADAGEYLR Phybl2 MRPLTAEETTTLFEKLAKYIGANIKHLIDFRLHNNRVYYLLGSAGVCFGKF-TKTGKFKLHITALDHLAQYAKK-IWIKPNGEMPFLYGNHVVKAHLGRITDDTPEHTGVVVYTMSDSPLGFGVTARSTVDMKKLAPTDIIMFHQADVGEYLR Picst3 MRPLTEEETKVVFEKLANYIGRNISFLIDFRLQKDRVYYVLMSLGTCFGKF-TKTGKFRLHITALPYMAQYAKK-VWIKQNGEMPFLYGNHVLKAHIGRMSEDIPEHAGVVVLSMHDVPLGFGVSAKTTNEARNLQPTGIVAFRQGDIGEYLR Plicr1 MRPLTEDESKAVFTKLANYIGKNLIQLIDFRLQKDRVYYVLVSLGTCFGKF-SKSGKFKLHVTALDYIAQYAKK-VWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVVFSMSDVPLGFGVTARSTVDTRKLDPTAIIVFHQADVGEYLR Polpo MRKLTDEETKVFFEKIIKYVGKNITLMVEFRVQKNKVYYILASLGTCFGKF-TKSGKFKLQITCLEYLAQYAKK-VWVKPQSEMSWMYGNNLLKAGLGRITEDTPQNQGVVLYSMNDIPIGFGVTAKSTGECRKLDPTALVVYHICDVGEYLR Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 MRPLTEDESKAVFAKLANYIGKNLVHLIDFRLHKDRVYYVLISLGTCLGKF-SKSGKFMLHISALDWLAQYAKK-VWIKPNGEMPFLYGNHVVKAHLGRITEDTPEHQGVVVYSMDDKPLGFGVTARSTIDTRKLDPTAIVVFHQADIGEYLR Rhior3 MRPLTSEETTTLFEKLAKYIGANIKHLIDFRLQKNKVYYLLASLGVCFGKF-TKTGKFKLHITALDYLAQYAKK-IWIKPNGEMPFLYGNHIVKAHLGRITDDTPEHTGVVILSMSDSPLGFGVTARSTVDMKRLQPTDIIVFHQADVGEYLR Rhoto1 MRPLTESETKALFSKLANYLGPNLVHLVDFRLHRSRVYYILISLGVCLGKF-SKTEKFRLHVTALDVLGRWAKK-VWIKPNGEMPFLYGNHVVKAHIGKTSEDITEHQGVVIYSMNDIPLGFGVTARSTVDTRKVDPTSIVVFNQADVGEYLR Rozal11 MRELTESETRVLFEKLSKYIGRNITDLIDFRLQKDRVYYVLLSLGVCMGKF-TKSGKFNLHITALDILAQYA---LWLKPSGEMSYLYGNHVLKAHIQKMSEDCPQHQGVIICSANDQPMGFAVSARAAVECKTLEPTAIVGYHQADLGEYLR Sacce1 MRQLTEEETKVVFEKLAGYIGRNISFLVDFRLQKDRVYYVLMSLGICLGKF-TKTGKFRLHITSLTVLAKHAKK-IWIKPNGEMPFLYGNHVLKAHVGKMSDDIPEHAGVIVFAMNDVPLGFGVSAKSTSESRNMQPTGIVAFRQADIGEYLR Salro MRPLTEDETTVFFEKLARYIGPNIRLLLDFRLHKDRVYYVLMGLGTCFGRF-NRSRKFRMHVTALPYLSAYAVK-VWVKPAAEQSFLYGNHVLKNGLARMTENTPQYQGVVVYNMNDLPLGFGATAKSTQECRTMDPTGIVVFRQADVGEYLR Schco3 MRPLTEDESKAVFTKLSNFIGKNLISLIDFRLHKDRVFYVLVSLGTCFGKF-SKGGTFKLHVTALDHLAQYAKK-VWIKPNGEMPFLYGNHVLKAHLGRITEDTPEHQGVVVYSMSDVPLGFGVTARSTVDTRKLDPTAIIVFHQSDVGEYLR Schpo1 MRPLTHEETKTFFEKLAQYIGKNITHLIDFRLQKDRVYYVLMSLGICFGKF-TKTNKFRLHITALDYIAQYARK-IWVKSNGEMPFLYGNHVLKAHVGRITDDTPQHQGVVIYSMNDTPLGFGVTARSTLELRRLEPTAIVAFHQADVGEYLR Sorma MRPLTETEQKTVFEKLANYC-TDLKSLIAFRLNHSRVYYVLLSLGTCLGKM-TKTGKFRLHITALPILSEHARK-IWVKDNGAQPFLYGSNVVKAHVGRWSEDCPEHSGVVVYSMADIPLGFGVTARSTTEARRLDPTGIVCFRQSDCGEYLR Sphar MRPLTEEETTVVFEKLVKYIGTNLKHMIDFRMQKDRVYYVLVSLGVCLGKF-TGSGKFRLQITALPQLAQYAKK-VWLKPQAEQSFLYGNHVMKSGLGRITESTEQYSGVVIFNMQDTPLGFGVAAYSTADCRKVDPTATVAFHQCDIGQYLR Spipu1 MRPLTEEETKIFFEKLAKYIGRNIVHLIDFRLQRDRVFYVLLSLGVCFGKF-TKTLKFKLHITALEYLAQYAKK-IWVKPSGEMPFLYGNHVLKAHLGRITEDTPEHQGVVIYSMGDVPLGFGVTARSTQDCRKLDPSAICVFHQADVGEYLR Sporo1 MRPLTETETKTLFSKLANYLGSNLVHLVDFRLHRSRVYYVLISLGVCLGKF-SKTEKFRLHVTALDLMGRYAKK-VWIKANGEMPFLYGNHVVKAHVGKTTEDIMEHQGVVVYSMNDIPLGFGVTARSTIDTRKTDPTAIIVFNQADVGEYLR Stehi1 MRPLTEEESKAVFTKLANYIGKNLVHLIDFRLQKDRVYYVLVSLGTCFGKF-SKSGKFKLHITALDYLAQYAKK-VWIKPNGEMPFLYGNHVAKAHLGRITEDTPEHQGVVVYSMNDIPLGFGVTARSTVDTRKLDPTAYIVFHQADIGEYLR Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr MRPLTEEEMKNVLEKLSHYIGSNIKLLVEFRLHKKRVYYLLVAMGTALGKF-TASGRFLLEITCLDYLAQYAQK-VWVKPSSELSFLYGNHVLKAGLGRITDGTPKNQGVVVYNMQDVPLGFGTTAYSTSDCRRVDGTAIVCFNQSDVGEYLR Treme1 MRPLSEDETKAVFEKLANYIGKNLVHLIDFRLHKDRVYYLLVSLGTCMGKF-SKTGKFKLGVTSLDWLARYAKKLIWIKPAGELPFLYGNHIVKAHLGRITEDTPEHQGVVVYNMADVPLGFGVTARSTLDTRKLDPSGIIVFHQADVGEFLR Trire2 MRPLTEEETQAVFKKLAEYTGASLKNIIAFRLSQNRVYLVLLSLGTCLGKF-TKSGKFRIHITALPILAEHARK-LWIRPNGVMPFLYGGNIVKAHVGRYSEDCPEHQGLVVYTMDDVPLGFGVSARSTAESRRLDPTGVMCFRQADCGEYLR Umbra1 MRPLTEEETKTLFEKLAKYIGSNIKHLIDFRLHKDRVYYVLGSLGVCFGKM-TKTGKFRLHITALDYLAQYAKK-MWVKPNGEMPFLYGNHVVKAHLGRVTEDTPEHQGVIVLNMSDVPLGFGVTARSTSDSRKLQPTDIVAFHQADIGEYLR Ustma22 MRPLTEEETKTLFEKLANYVGKNLVNLIDFRLHRDRVYYVLMSLGTCFGKF-SKTGKFRLHVTALDYLAQYAKK-VWIKPNGELPFLYGNHVVKAHLGRITDDTPEHAGVVVLSMSNTPLGFGVTARSTVDTRKQDPTSIIVFHQADVGEYLR Walse1 WRPLTEDETRAVFEKLANYVGKNLVHIINLRLQKDKVFLLLISLGQCLGKF-TKSGKFKLGIGSLDVLARWARK-VWVKPNGELPFLYGNHVVKAHLGRITEDTPEHQGVVVLSMSDIPLGFGVSARSTVDTRKLDPTGLVVFHQADVGEYLR Zygro1 MRQLTEEETRVLFEKLAGYIGRSISNLVDFRLQKDRVYYVLISLGTCLGKF-TKTGKFRIHVTALPILAPNAKK-VWIKPNGEMPFLYGNHVLKAHIGKMSEDIPEHAGVIVYSMNDIPLGFGVSSKSTNECRDMQPTGIVAFRQADIGEYLR [Cluster1444.fasta_al_trimmed; alignment length = 150] Allma1 ITDAVGVLEAALRQFTPKLALSFNGGKDCTVLLHLLVAVQTVYVGFNEEHEFVYNLAVMQSALATYTIRAVCVGTRRTDPWASHLDPGWPDLVRVHPVLDWAFADIWLFLLVEYCVLYDGYTSLGPKDRTVPNPDLYWPAWRLRDERCGR Ashgo11 TQNAIRVTQDVFPKWNPLISFSYNGGKDCQALLVIYLALPAVYITYGSLENFVYALALMAEAFKDYLTKAIVIGIRHTDPYAEKLDAGWPEFIRVQPLLHWKLANIWSFLLEEICGLYQGFTSIGGINSTTRNPYLYLPGWFLINERAGR Aspfu1 TRISLNVIATALSRYKLSLSLSYNGGKDCLVLLILFLAIPAIYASFPAVEEFVYHLAILKSCFEHYLIKAIFVGTRRTDPHGANLDSGWPDFMRIHPVIDWHYAEIWAFIRLKYCSLYDGYTSLGGTSDTHPNPKLYRPAYELTEERLGR Aurde31 VKEAIGVIERALDDQGEEVALSFNGGKDCTVLVHILAAIPTIYISFAEMENFIYALELMKTALAAYKMTSIFVGTRRNDPHGGSLDPDWPQFLRVHPIINWSYSSVWQFLRVPYCHLYDGYTSLGSTYNTFRNPALWKPAYELQDERAGR Batde5 -------------------AVSFNGGKDCTITLFLYAVIKLLYVSFPEIEQFVLRADLMKVALKKFLVKAILMGQRATDPHSDQLNNGWPFVMRVHPILDWEYEDVWAAILIPYCSLYSGYTSIGNVKDTLPNPLLYLHAKYLEDERSGR Botbo1 VREALQVIEDVLKTHGLDVAISFNGGKDCTVLLHLFAALKSVYIPFTSVEDFIYNLRIMKEALREYLVKAMLVGTRRNDPHGAKLDNGWPALLRVHPIINWSYRDVWDFLRVPYCDLYDGYTSLGSTYNTFPNPALYRPAYELIDERAGR Botci1 TRIALRVIGECLERYSLEISFSYNGGKDCLVLLILLLALPSVYIPFPEVDTFVYHLRLMKEAFTQYLVKAILVGTRRTDPHGADLDGGWPRFMRVHPVIDWHYREIWGFIRIPYCPLYDGYTSLGGTTDTHPNPVLFRPAYELVEERLGR Caeel LNEAESIVEEIVEKYPLEIALSFNGGKDCTVLLHLLRLIQGFHIQFPEATQFIYNIQVLKTGLAALKIIPVLMGSRATDPNGKYMDSDWPQVLRVCPILNWTYTDVWHMLRVPYCKLYDGYTSLGGRDNTVKHPALYLPAYKLHNERCNR Canalb1 VLLSMEKLESSIDLHGLQIAISYNGGKDCLVMLILLMALDSIYIPFPQLVDFIYHLNPLKDGFEYYLVKSVIVGIRHSDPYGETLDHNWPKFLRIHPILHWNYVDIWDFLIVKYCEMYDGYTSLGGINSTVPNPLLYQPAYMLKEERLGR Cangl TQRAINTTKETFPKWSPLISFSYNGGKDCQVLLLLYLSLPTVFITFKTLENFIYSLSLMAEAFETFLTKAIVIGIRHTDPFGEHLDANWPDFYRLQPLLHWNLANIWSFLLEPICELYRGFTSLGNVEETLPNPHLYYPGWYLVDERAGR Capow VRQATTAIEQALQIYKTDIMLSFNGGKDCMVVLHLLNAIPAIYLQFHEVESFVYSMDLIKAGLTELSVRAIFAGTRRTDPFSASLDPDWPQFMRINPILDWSYADVWLFLRVPYCHLYDGYTSLGGRSTTSPNPALFSPAYLLQDERDGR Catan2 IPPAVHILEHALDKYGPDFGLSFNGGKDCTVLLHLMAAIRTVHVGFVEEDAFVYNLDLMQPGLSVFHIHAVAVGTRRTDPWCQHLDKGWPDLMRVNPILDWQYSDVWLFLHVEYCVLYDGYTSLGSKARTVRNPALYWPAWRLMDERCGR Cioin VKSSLEVLEETLRKYEPHICVGFNGGKDCTALLHLYHAFKALYIPFEEVEQFMYKFHLMKQALEALKIKAVVMGTRCSDPHSMDLDSDWPRFMRVNPLLHWTYHDVWKFMRLPYCVLYDGYTSLGSRDKTERNKKLYLPAYTLQDERNGR CocheC53 TQTSLQVLAEALDRYTLPLSLSYNGGKDCLVLLILYLCVQCVYIPFPEVEEFVYSLSLMKAAFADYLVKAILVGTRRTDPHGEHLDSGWPAFVRIHPVIDWHYAEIWTFIRIPYCSLYDGYTSLGGTTDTHPNPKLFRPAYELIDERLGR Coere1 VSSALRIIEQAIEQYGPSLALSFNGGKDCTALMHMVRALVTLCVQFLEIDDFVYNLELMKQGLQSFKIQAIFVGTRRDDPYSSTLDNDWPRFMRVNPIIDWSFDDIWEYIHVHYCCLYEGYTSLGDVDSTVRNPALYQPAWLLTNERNGR Conco1 LQEAIRIIDEAIDRYG-DLAFSFNGGKDCTVILALYSIIPALYISFSEIDEFVYNIDLMKVGLLQFLIKAILIGTRKTDPYGHLLSEGWPECMRVHPILDWSYNAIWDFLLVPYCSLYDGYTSLGDKNNTHPNPLLYSPAYLLKDSRAKN Conpu1 VKTALGIINDALEKNGEKVSLSFNGGKDCTVLLHLYIATQALYIPFPVLEEFIYNLRLMKRALERYKITAILIGTRKTDPHGATLDSGWPEFDRVNPILNWSYADIWKFLLVPYCSLYDGYTSLGSTYNTFPNPALFRPAYELEDERAGR Copci VKEALDVIDEALDTHGPE--------------------IESVVTEGVKADDYI-----MRQALQAYKIAAILIGTRRTDPHGATLDPGWPRFERVNPIINWSYQDIWTFLRVPYCSLYDGYTSLGSTYNTFPNPALYLPAYELKDERSGR Croqu1 VAQALDVIQKSILEYGADVALSFNGGKDCTVIIHLLAAMRALYIPFGEVEDFMYNVELLKDGLQAFLRRAILIGTRSTDPNGARLDNDWPSVMRIHPILSWSYHDIWDFLRVGWCELYNGYTSLGSTFNTRPNPHLWRPAWELTDERAGR CryneH991 INEALVLIESVIDILGEEVAISFNGGKDCTVLLHLYAAIRSIYIPFAELDEFVYGLDLMKAALEEWLVKGVLVGIRQGDPNDA--DPSWPQFIRVHPILHWAYSDVWNFLLVPYCILYDGYTSLGSTTNTLPNPLLWEPAHRRKSERAGR Crypa2 VREAVSVIDEALDKYSLELSLSYNGGKDCLVLLILILALQSVYIPFAEVDTFVYHLDLMRAALDAYLLRAIFVGTRRTDPHGADLDDGWPAFMRVHPVIDWHYAEIWAFIRIPYLSLYDGYTSLGGTEDTHPNPHLFKPAYELTEERLGR Debha1 IHKSLQVFDKAIEIHGLEIAISYNGGKDCLVMLILLMALDSIYIPFPNLSDFIYHLNPLKEGFEKYLVKSIFVGIRYSDPYGSSLDHDWPGFLRIHPILHWKYEDIWDFLILDYCEMYDGYTSLGGINTTTPNPYLYSPAYMLRKERSGR Dekbr2 VRNTLRIYRNALDDFGLSISISYNGGKDCLVMSVIYLAINSVYITFREQDAFLYGLDFMKEGFQEYLIKAIIVGIRRIDPYGAHMDNGWPDFVRLSPVLEWNTSEIWYFLRTSYCSSYNGYTSLGGVNTTIPNPLLYLPAYMLQHERLGR Dicdi IMESIETIECAFNKFEFQIALSFNGGKDCCVLLHLINYLKTIYFSFNQVNEFTYNLNLIKEGLEKIIIKAVFIGIRFGDPNSLHLDPGWPHFLRVNPILNWNYHEIWEFIKIPYCELYDGYTSIGQQHDTIPNPDLYYHANRLENERKGR Dmel SENSKDVAKETLQIYGVELIFCFNGGKDCTVLLDLLMRM--LYISFPEIDEFVYRVQLLKEALTHMSIKAVFVGSRNTDPYCQHLDNDWPPMMRLNPLLEWSYHDVWHYIHVPYCSLYDGYTSIGNRANTVPNPHLYRPAWELQDERAGR Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------ Falba VRQSLAIIEHAMDLYDGPVAVSFNGGKDCTVLLHLFAATAGFCIPIPRISEFVYHLDWMKAALAGLLLGAILMGTRKTDPHGEYVDRDWPQFMRVNPVLEWSQPDVWSFLRVPYCSLYDGYTSIGSHANTFPNPWLFLPAYCLQDERDGR Fomme1 VREALCVINQALDEHGQDVSLSFNGGKDCTVLLHLFVAIPTLYIPFPELEEFIYNLDLMRRALEVYKIEAILVGTRKDDPHGATLDADWPQFERVHPIINWSYTDVWTFLRVPYCILYDGYTSLGSTYNTYPNPALYRPAYELLDERAGR Fusgr1 VRKSIEAVDEALHRYRPEISLSYNGGKDCLVLLVVILALQCVYIPFPEVDEFVYGLEVMKKGLEIYLIKAVFVGTRRTDPHGENLDAGWPSFMRIHPVIDWHYVQIWAVSSVPF---------------TIKAIRV-------------- Galma1 VKEALGVIDECLDTHGPDVALSFNGGKDCTVLLHLYAGIHAIYIPFKSLEDFIYNLDLMREALATYKITAILIGTRRTDPHGAKLDAGWPAFERVNPIINWSYTEVWSFLRVPYCCLYDGYTSLGSTFNTFPNPALYHPAYELQDERSGR Ganpr1 LAKSLRIVEEAVEKYGPQLALSFNGGKDCTVLLHLFASMKTLYVQFSEVDEFVYGLRAMKPALQTYLVKAVLVGTRRTDPFGEFLDPGWPAVMRVHPVLDWSYDDIWTYLRVPYCTLYDGYTSLGSTDTTFPNPQLYDPAWKLADERDGR Gloin1 --------------------------------------IQALYVPFSEVDEFVYCLNIMKPALIKYLIKAILVGTRRNDPHGGKLDDGWPSIMRVHPILDMHYTQIWEFLRVPYCVLYDGYTSLGSKNNTYRNPDLYDPAWKLTDERCGR Hisca1 TRISLNVIQEALKRFSLNLSLSYNGGKDCLVMLILFLSIPAIYAPFRSVEEFVYHLSLLRTVFASYLIRAIFVGTRRTDPHGEKLDHGWPGFMRIHPVVNWHYAEIWAFIRIEY------------------------------------ Klula1 TQESIQLSRDIFTRWDPFISFSYNGGKDCQVLLIIYLGLPTVYITFLTAQDFLYHLSLMPSAFKSFLTQAIVIGIRHTDPFGETLDPSWPQFYRLQPLLHWNLSQIWSFLLEEVCGLYEGFTSLGSVNNTLRNPYLFHPGWYLTKERAGR Lacbi2 VKEALEVIDHALDTHGQDLSISFNGGKDCTVLLHLYAGIHSIYIPFPSLEAFIYNLDLMLHALAMYKVTAILIGTRRTDPHGATLDPGWPCFERVNPIINWSYADVWKFLRVPYCDLYDGYTSLGSTYNTFPNPALYRPAYELTDERCGR Lenti61 VKEALEVIDEAFETWGQEVSLSFNGGKDCTVLLHLVAALAAVYIPFPQLEEFIYHLDLMRLALEMYKVEAILIGTRRSDPHGAKLDPGWPRFVRVNPIINWSYADVWAYLKVPYCNLYNGYTSLGSTYNTFPNPALYRPAYELADERAGR Malgl1 VASALEACESALHDYGVNCALSFNGGKDCTVLAHILCAIRSLYVPFPEVEAFIYNLQLLSSALGTYI-RAMFIGIRHDDPHGSSLDPSWPPIMRVHPILDWNYTDIWSFLRVPYCILYDGYTSLGNRFNTIPNPELYKPAYRLCDERFGR Mellp23 VKQALDTIEQSILDFGPEVALSFNGGKDCTVIIHLFAAMRALYIPFDAVEDFLYRLELLKDGLQAFLRRAILIGTRSTDPNGANLDSDWPAVMRIHPILDWSYHDVWDFLRVGWCDLYDGYTSLGSTFNTKPNPYLWRPAWELEDERAGR Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 VRHAVEVIEEAVRRYGPAISLSFNGGKDCTVILHLFVAIASIYVPFGQVERFVYNLNLMKKALEEY-VSAIMVGTRRDDPHGGPLDPSWPPFMRIHPILDWTYHDIWTFLRVPYCGLYDGYTSLGGRDNTFPNPELFGPAWKLSGERCGR Mucci2 VKVALQVIEQAYQEYGFDVALSFNGGKDCTVLLHLVAALRTVFVPFPHVDAFVYKLDCMKQALQQYITKAIFVGIRRTDPYAEKLDQGWPDFMRVQPIIDWSYKNIWDFLLIPYCSLYDGYTSLGSMENTYPNPELYRHACRLTDERDGR Mydma IKCAWAVFKQTFDMYSPNVCIGFNGGKDCTVVLHLIMALIGLYFQFPMVQQFIYKFKLIKAGLNKLKLKAIIMGTRRCDPFSSHLDKGWPEFMRVMPLLDWSYGEVWQFLKKPYCKLYDGYTSLGSSKNTEKNPALYLSAYNLENERLGR Neucr2 ARDAMEVIEEALRRYRPELSLSYNGGKDCLVLLILILALQCIYIPFQEVEDFVYHLDLMRQALDSYLVKAVFMGTRRTDPHSEFLDKGWPQFMRINPVLDWHYVEIWTFIRIPFCSLYSGFSSLGGTKDTRPNPALFRPAYELTRERLGR Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 TRISLDVVNTALQRYKLSLSVSYNGGKDCLVLLILFLAIPAIYAPFDAVEDFVYHLAILRSSFEDYLIRAIFVGTRRTDPHGAQLDGGWPDFVRVHPVIDWHYAEIWAFIRLKYCSLYDGYTSLGGTSDTHPNPRLYLPAYELTEERLGR Phybl2 VKEALSVIEQTYKTYGLDTALSFNGGKDCTVLLHLVVALRTVFVPFPHVDAFVYHLDCMRPALQEFLPKAIFVGIRRNDPYAETLDKGWPDFMRVHPIIDWTYKDIWGFLLIPYCSLYDGYTSLGSMENTHPNPQLFKPAYMLQDERCGR Picst3 VLLSMEKLNCAIENHGIEIALSYNGGKDCLVVLIILLALDSIYIPFPELTTFIYHLNLLKLGFEKYLVRSIVVGIRFNDPYGSNLDHDWPKFLRIHPILHWNYVDVWDFLILDYCEMYDGYTSLGGINNTIPNPYLYLPAYTLTEERLGR Plicr1 VKEALDVIDQGLDSHGQEVSISFNGGKDCTVLLHLFAGIPAIYIPFPALETFIYNLDLMRRALEVYKIRAILIGTRRADPHGAALDPDWPQFERINPIINWSYTDVWTFLRVPYCHLYDGYTSMGATYNTFPNPALYRPAYELLDERAGR Polpo INKSIATIELTFNKYKFEIALCFNGGKDCVVLLHLMNYLRTLYFSFKEVTKFTYNLH-LKDGLEQQVIKAIFAGTRSTDPYSSHLDPSWPQFIRVSPILEWNYADVWKFIRIPYCVLYDGYTSIGHVNDTIPNPALYLPAYHLKDERSGR Pucgr2 IKHALEIIELAIVRFGVDLSISFNGGKDSTVLVHLFAAISGLYIPFAEVDEFVYNIDLLKNGLGAFLIKAILIGTRATDPNGGSLDSDWPSIIRVHPILDWGYSHVWEFLQVDWCKLYNGYTSLGSSFNTFKNPFLWKAAWELSDERAGR Punst1 ILEALHVIEEAIDTHGQEVSISFNGGKDCTVLLHLFVGIPSIYIPFPEMEAFIYNLDLMRRALDMYKIDAILVGTRRGDPHGAKLDPGWPQFERVHPIINWSYSDVWAYLLVPYCRLYDGYTSLGSTYNTNPNPALYRPAYELIDERAGR Rhior3 LRKALEIIEIAYKKYGVEISLSFNGGKDCTVLLHLVAAIKTVYVPFPHVDAFVYGLDCMKSALQRYMLQAIFVGVRRTDPYA-------------------------------------GKCS--------------------------- Rhoto1 VREALDIVERALDEYGLEIALSFNGGKDCTVLVHLLAAIPTIYVPFPQVEAFVYALELMREALQVYVIKAVLVGTRRNDPHGEHLDAGWPDFMRVHPILDWSYGDVWAFLRLEWCELYDGYTSLGSTHNTFPNPLLWRPAWELVDERAGR Rozal11 IRHTLSILETAFERY--NLAISFNGGKDCTVLLHLLYSIPALYVSFPQVELFVYPIKVMKQALSSFKCKAIFIGTRRTDPYSKDLDKDWPRFMRVNPILDWSYHDVWEYLRVPYCSLYNGYTSLGGLKDTFPNPALERGAWNLVDERNGR Sacce1 TQEAIRLTREIFVRWSPLISFSYNGGKDCQVLLLLYLSLPTVFITFPTLENFVYCLSLMADAFRDFITEAIVIGIRHTDPFGEALDSNWPDFMRLQPLLHWDLTNIWSFLLEPICGLYGGFTSIGGINNSLPNPHLYYPGWYLVDERAGR Salro VRAAISTIRTTVELFGFSTCLSFNGGKDSTLLLHLVMEITFVYFEFPQVEDFIYGLSLYGTALEGLLIKAIFMGTRRGDPKADTLDPGWPTFMRVHPVLDWTYAQVWEYLRKPYCSLYDGYTSIGNMLNTVPNPRLFLPAYMLEDERCGR Schco3 IKEALTVIEEALDDYGFDMSISFNGGKDCTVLLHLYVAIPALYIPFPALEEFIYNLDLMKQALQIYKISAILIGTRRSDPHGARLDPGWPDFERINPIINWSYKDVWIFLRVPYCCLYDGYTSLGSTFNTFPNPALYRPAYELTDERAGR Schpo1 LSISLRFIEYAFETYQPELAMSFNGGKDCLVLFLLCIYIPFVFVEFPEMDDFVYRLNIMKEAFCKFLIQAILIGIRRLDPHGLHRDKGWPKFMRIQPILDWSYTEIWDLLLTKYCSLYDGYTSLGGVSDTSPNPALYSPAYLLSDERAGR Sorma ARDAMEVIEEALRRYRPEISLSYNGGKDCLVLLILILALQCIYIPFREVEDFVYHLDLMRQALDIYLVKAVFMGTRRTDPHSEFLDKGWPQFMRINPVLDWHYVEIWTFIRIPFCSLYSGFSSLGGTKDTRPNPALFRPAYELTRERLGR Sphar IRHSLEVLQRAIDLYGIHISLSFNGGKDCTLVLYLWVAIHTLYVCFTEIQEFVFNLDLIKEGLGTMLIKGVIIGARHTDPFYGNMDEDWPQVMRIHPILQWSYQNVWECLLEPVCELYKGYTSVGNTHNTHPNPALYDPAWKLTDERAGR Spipu1 VDESFKIIKEALKRYGPDVALSFNGGKDCTVLLHLLYAIKTLYVSFPEVDDFVYNLELMRAGLQVFLTKAMLVGTRRTDPFGEHLDPDWPTLMRVHPILDWNYADIWKGLAIPYCILYDGYTSLGAIDNTIPNPALFDPAHRLADEREGR Sporo1 --------------YRIHLALSFNGGKDCTVLVHLLAAIPTIYVPFPQEEHFTYHLSLMKDSLRTWIIKAVFVGTRRTDPHGHTLDPTWPRFMRCHPILDWDYHQVWQFLRIEWCELYDGYTSIGSTHNTFPNPCL-------------- Stehi1 VHEALTVIDQALDAFGLDVSLSFNGGKDCTVLLHLYAAIPTLYIPFPALETFIYKLDIMRLALEIYKIEGIFIGTRRTDPHGATLDKNWASFTRIHPIINWSYANIWTFLRVPYCSLYDGYTSLGSTYNTFRNPALYRPAYELTDERAGR Tapde11 TREALKVIEDAYARFSDEIAISYNGGKDCLVLLVLLVAIKSVYVPFTEVDEFVYNLEVMKEAFAEYLIRAILVGTRRNDPHGAHLDQGWPKFMRVHPIINWKYAEIWDFLRVPYCDLYDGYTSLGGTGDTLPNPSLYRPAWQLNDERRGR Thetr LRTSLEIIAKAYEEYGPPLSLSFNGGKDCTVLLALIGAWHAAYLPFPVVEQFISGIELMKATLERLLLKAMFMGTRRGDPYSDHLDDGWPALMRVFPLLHWSYKHVWDFLRVPYCELYDGYTSLGDVHNTLRNPHLYLPAYALTDERSGR Treme1 IAYALQLVDRVLTDLGEHVAISFNGGKDCTALLHLYAA---------------YGMDLMKGALCSYLVKGVLMGTRKGDPNGA--DPSWPSILRIHPLLHWSYADIWDFLLVPYCELYDGYTSLGSKHNTLPNPLLWEPAWKRGYSRSKP Trire2 ARVSVRVVEEALERYRPELSISYNGGKDCLVMLIVLLALRAVYIPFAEVDDFVYHLDVMKKGLEVFKVRAIFVGTRRTDPHGEKLDEGWPDFMRIHPVIDWHYTEIWAFTRLPYCPLYDGYTSLGGRKDTLPNPRLFRPAYELVEERLGR Umbra1 VREALNVIEEAVDKYGQGLSLAFNGGKDCTVLLHLVIAIQSVYVPFPEVDDFVYRLESMRLALQQFIPEAILVGIRRSDPYAENLDEGWPSFMRVHPIIDWSYQNVWEFLLIPYCELYDGYTSLGGMDNTFPNPELFNPAYMLTDERCGR Ustma22 VQSAVQLCEQVIHEVGQQCALSFNGGKDCTVLVHILSAIPSLYIPFPTVEKFIYNLQVMKKGIRTYLIRAMFVGTRRDDPHGPQLDKDWPRVERIHPILDWSYQDVWHFLRVPYCLLYDGYTSLGSTHNTLPNPKLWRPAYMLKDERAGR Walse1 EKNGYSIIKKIFQDYASEISLSFNGGKDCTVIAYMIKKTKSLYIPFKEVDNFVFNLDIMKQSLEEFIIKVIIIGTRESDPNGTNLDKDWPCILRVHPILHWNYHQIWEFILIPYCNLYDGYTSLGSTFNTHQNPQLYRRAHELIEERSGR Zygro1 TQNAIKLTQEIFPRWSPFISFSYNGGKDCQVLLIIYLGLKAVFITFQTLEQFVYSLSLMPEAFHKYLTKAIVVGIRYADPFAQDLDDGWPDFLRLQPLLHWKLAYIWSFLLEPICGIYSGFSSLGDINHTLPNPYLYLPGWYLLDERCGR [Cluster1459.fasta_al_trimmed; alignment length = 342] Allma1 GNIVLLTFLYLLQGVPVGLAFGTLPFLLKLSFSDMAVFSL-AGYPYSLKLLWSPIVDSIFSIGRRKSWIIPIQLITGLMFYILSQSIWWTTIWFLVIFLCATQ-DIAVDGWALTLLSNMQFASTCQTVGINCGYFLSFTVFLAFNSAEFCNKYTKPILTLGPYLALWSVAITFWVTFFKRETYKTIHGIIKLPHMIKFILVLLFAKIAFICNEAVTALKLLELG-IQKEDLALAVLVDFPFQILFGYFAAQWSSLRPWLYAFYGRLAFSLFSSFMSTV--QFVSLGAFFSHV--ADPVIGGTYMTLLNTLSNFGGTWPRYFVLVEYLTVATCASFLLGLVLL Ashgo11 PQFYLLVALYFLQGIPVGLAFGTVPFLLKTSFTKLGLFGI-ATYPYSLKILWSPLVDSVFKIGRRRSWIIPVQLASGVMLWCVGHAVSLTVCFLVLVFFCATQ-DIAVDGWALTILSSLSYASTAQTVGLNTGYFLSFSIFLAFNSGDFVNRYDHGIISFSSYLKLSGLILTAYVVFFTQEVYRSFVKVLRLPAVRSLIILHFVSKFPFQCSEGATNLKLLEKG-LKKEDLAITVLVDFPFEIIFGYYVAKWSSLTPWIIGYIGRLIASMLGSFMSTV--QFVGVSAFHTRI--ADPAIGGTYMTLLNTLSNLGGTWSRIVVMIDFFTSKVCLCIGFGLLI- Aspfu1 RNFLLLCVLYFLQGVPMGLATGSVPFLLKLSYGQIGVFSL-ASYPYSLKLLWSPIVDAVWRFGRRKSWITPVQVIAGLAMIYLGGHINFTYWWFLLVFFCATQ-DIAVDGWAITLMSNISYASTAQTVGLTAGHFLSYTVFLAFNSKDFANRWEDGLLSLGGYLTFWGLFVTICLALMKKEVYKSMWNILKLKNIQTIIVIHLIAKIGFQANDAVTSLKLLDKG-FGTDNMALVVLIDFPFEIGLGYYAGKWSTMRLWCWAFIGRLAAAVLSTFMNTV--MFVAVSAFHARI--ADPAIGGTYMTMLATVSNLGGTFPRYFILVDFFTVATCLCVLVGTVTF Aurde31 QGMVLLVVLYLIQGVPLGLSLGSIPFILRLSYSQLGVFAL-SAYPYSLKLLWSPVVDSLFAIGRRKSWIMPMQLIIGVTMLWIALNVRLTIIFFSLVFFSATQ-DIAVDGWALTLLSNVSYASTAQTIGLNTGFFMSFTCFLAFNNVEFTSKWGIPRLTLTAYMGFWSITVTLVLLLFKKEVYGIMWKICRLRNVQLLLLLHFVAKIGFQANDAVTSLKLVEKG-LSEADLALAVLIDFPCQLVGGYYAAKWSNLRPWYYAFWARLFFAGVSSFASTI--QFVGVTAYHTRI--ADPVVGGTYMTLLNTASNLGGTWPRYFVLVDLFSVAKCICIVTGTILF Batde5 GNMVLLVFLYLLQGVPLGLSMGSVPFLLKLGFGDLALFSL-SSYPYSLKLLWSPIVDSTYSIGRRKSWIVPIQAILGISLLVLGGYIMLATVFTFMVFLCATQ-GIRLRVSTLHIYILITYASTAQTIGLNTGYFLSFTVFLALNSPELCNKYDVGLVQLGPYLQFWGLICNAWLVFIKKEVYHTMVKIIMLPHMKTFIAVLLVAKLGFVANDAVTGLKLLEKG-FSKEDLALAVLIDFPFQIVFGYYAAKWSNLKPWLWAFYGRLFAAFLSSFMSVL--QFIGMGSFFTKI--SDPAIGGTYMTLLNTLSNLGGTWPKYFVLVDYYTDAPCGCMVIGVAIL Botbo1 RAMALLIVLYLIQGIPIGLSFGSIPFLLKLSYSQIGLFSL-CTYPYSLKLLWSPIVDSIYRIGRRKSWIVPIQAIIGSLMIWIGRHSKLTILFTALVFFAATQ-DIAVDGWALTLLSNLSYASTSQTIGLNCGFFLSFTVFLAFNSADFANKWDAPFLSLGTYLTFWGFVVTLLLFFFKKEVYKIMWSICKLKHVQALCLMHLVSKIGFQANDSVTDLKLLEKG-LGKEDLALIALIDFPFQLIGGWFAASWAKLRPWLHAFWVRLVFCVIGSFAGTV--QFVGVSAFHTQI--SDPLVGGTYMTLLNTVSNLGGTWPTFPVLVDALTIATCICVTIGAVLF Botci1 RNFLLLVLLYFLQGVPMGLATGSVPFLLKMSYSALGVFSL-ASYPYSLKLLWSPIVDAIWKVGRRKSWIMPIQMLSGLGMIWLGSQIGFTGWWFFLVFTCATQ-DIAVDGWALTLLSNISYASTAQTVGLTAGQFMSFTVFLAFNAPDFANKWDEGVMTLGGYLTFWGIIVTLGLALLKREVYKVMWGVLKLKNIQTIIIIHLIAKIGFQANDGVTNLKLIDKG-FSQEDMALTVLIDFPFEIGLGYYAGKWSTLRLWCWGFVGRLIAAVISTFTNTV--MFVAISAFHARI--ADPVIGGTYMTLLATVSNLGGTFPRFFVLVDYFTTATCICVIFGAVTF Caeel SSILLLLFLYLLQGVPLGLI-GAIPLLLSVSYGSQAIFSF-AYWPFSLKLLWAPIVDSVFRLGRRKSWMVPCQYLIGAFMLYLSYKVFLMLIFLPLNFLAATQ-DIAVDGWALTMLSNVGYASTCNAVGQTAGYFLGNIVFLALESPTFCNDFDTGIIDLAGYVFFWGIVTTTLVLVLKRESYAVLYKILKLKSIHYMVAILLTGKLAFAASDGMTSLKLIEMG-IPKDRLAGIGVFLTPMQIMLPWMIGKWTALNVFLLAFPYRIFIGGVHQLATYS--MFVSMMAFIAQI--SDPRIGGTYMTMLNTLNNLGGNWPVTVVLTDWFTYKDCICSVIGVIWY Canalb1 KAFIILVLLYVLQGVPVGLAFGSIPFILKLTYSQVGIFSL-AAYPYSLKLIWSPFVDSIYKWGRRRSWIIPIQTISGIMLILLGTQILITMVFFILILCCATQ-DIAVDGWALTCLSSLSYASTAQTIGINTGYFSSFTIFLALSSPDFANKYDVGLFSLGGYLKFWGLIVTGIICLVPEDVYKSMYEVLKLPNVQTFVIILLIAKLGFQVNEAGTNLKLLEKG-LSKEDLSITVLIDFPFEMIFGYYAGRWSTLRPWLWGFMGRLVAASLGSFMSTI--QFVSLCAFHTKI--ADPAIGGTYMTTLNTLSNYGGTWPRIFIYIDKITINKCLCISLGIVIF Cangl PQFYLLICLYFLQGIPVGLAFGTVPFLLKTTFTQLGIFSM-ATYPYSLKILWSPLVDSVYKIGRRRSWIIPIQLVSGVMLFFLGTCIFLTWCFGTLVFLCATQ-DIAVDGWALTILSSISYSSTAQTIGLNMGYFLSFTVFIALNSSEFANKYPHGLISLGGYMKTAGVLLTLYVIFFTKEVYRGFLKILKLRSVRTLATIHMVSKFAFQCNEAATNLKLLEKG-FKREDLAVTVLIDFPFEIIFGYYVVKWSSLTPWLWGFLGRLTAAMFGSFMSTV--QFVAISAFHSKI--ADPVLGGTYMTLLNTLSNFGGTWPRLMIMINYFTVYSCFCIIIGTLLY Capow GHMVLLVLLYVLQGVPLGLVGASIPFLLQASYTDLAVFSL-AGYPYSLKLLWSPIVDSVYPLGRRKTWILPTQTLLAVLFVYLGSTIWLSVTFFVVIMCAATQ-DIAVDGLAIEVLSKRAYSSTCQSIGLTAGYFISFTVFLAFNSVDFCNSYDWPIIQLGPFMMFWGATVTGYLVLVYQEVYMQLLSIVRSKQMRVLISVLLVQKIGFLASDVVSMLKLVEKG-FDKTDLGLVALIDFPCQLILGIYVARWTSLKPWLSALYGRLFLSLALSITSTA--MFVAQGAFFARI--SDASIGGTYMTLLNTVSNFGGTWPKFFILVDMLTVSHCICFVLGAVVL Catan2 ----------MLQGVPVGLAFGTLPFLLKLSYTDMAVFSL-AGYPYSLKLLWSPIVDSVFSIGRRKSWIIPIQLFTGLTFYWLSRNVLITAMWFFVIFLCATQ-DIAVDGWALTLLSNMQFASTCQTVGINIGYFMSFTIFLAFNSAEFCNKYDLGLLQLGPYLGFWAIGLTLWVAFFKDETYLTIMDIIKLPHMLKFIAVLLLAKVAFICNESVTALKLLEKG-IQKEDLALAVLIDFPFQILFGYLAAQWSSLRPWLYGFIGRLAISLVGSFTSTV--QFVSMGAFFSTV--ADPLIGGTYMTLLNTVSNLGGTFPKAFVLVDYFTTATCASFVLGLLLL Cioin --VLLLLFLYVLQGIPLGLA-GSIPMLLAVDYKQQALFSF-VFWPFSIKLLWAPIVDGAYSIGRRKTWLVPTQYVIGTIMFILSYKLNLTVCFFILNFCAATQ-DIAVDGWALTMLSNVGLASTCNSVGQTAGYFLGYVVFLALESADFCNKYEEGLVNLSGFMYFWAIITTTLVMIFKKETYKLLFKIICLPNVLQYVVILLTAKIGF-ASESIVALKLIECG-IHKETLALLAIPLTPLQIALPVIIAKYTSLDIFLKAIRYRLIFTLLHQVTLYS--MFVAVMAFNAKI--SDPHIGGTYMTLLNTVANLGGNWPSTLALVDALTTTNCLCLILGILWL CocheC53 SNFLLLVLLYFLQGIPMGLAHGSVPFLLKVSYAAIGVFSL-AAYPYSLKLLWSPIVDAVWTIGRRKSWILPIQTISGFSMIWLGKNINFTWWWFALVFLCATQ-DIAVDGWALTLLSNLAYASTAQTVGLTAGQFLSYTVFLAFNSKDFANRWETGIMELDGYLSFWGLIVTFGLAVMKREVYRTMWGILKLKNIQSFIIIHLIAKIGFQANDAVTSLKLLDKG-LKQEQLSLVILVDFPVEVFLGYYIGKWCQMHIWCWSFVGRLVAAGFSTFMNTV--MFVAVSAFHAKI--SDPLIGGTYMTLLATVSNLGGTFPRYFVLVDMFTSATCLCILIGVLTF Coere1 GNIMLLIALYWLQGIPLGLAHGSIPFLLKLSFAQVGLFSL-AGYPYSLKLFWSPLVDSVYKFGRRKSWIAPIQLITALIFWWMGSHIEITYLFLAIVFLSATQ-DIAVDGWALTLLSNLPLASTCQTVGINCGFFLSFTVFLALNSVEFSNKYDAGFLQLGPYMAFWAVVVTLYLIVFKRETYRTIWRICKLPHMQQFIAVLLVAKLGFIPNDSTTQLKLIERG-LHREEMALAVLIDFPVQLIFGYYAATWSQMKPWRVAFILRLLCSVLSSMASTV--QFVCISAFVAQI--ADPVIGGTYMTLLNTLSNFGGTWPVFFVMIDYFTSATCACVLLSMFLF Conco1 GNFALLVILYLLQGIPTGLTFGSIPFLLKLSYSELAIFSL-TGYPYSLKLFWSPIVDSIYSIGRRKSWIIPIFFILGFLLYYLGIHLPLTTVFCTIIFLAATQ-DIAVDGWALTLLSNIAYASTSQTVGLNAGFFVSFTIFLALNSVEFGNKYTEPLVSLSGYLSFWAFIVAIYLILFKDETYTTIFDICKSKHMMTFIAILLTAKIGFVANDSVTNLKLIEQG-FPKEDLAFTSFLDFPLQLIFGFYIAKVTTLKPWLYAFYAKLASCLLHTLSSTI--MFVGMGAFFSMI--ADPTIGGTYMTVLNTINNLGGTWPQFFILVELFTKAECLTVCIAFVLS Conpu1 RAMALLITLYLIQGVPLGLALGSVPFLLKLSYSELGVFSL-SNYPYSLKLLWSPIVDSLYSIGRRKSWIIPMQLVVGSLMVYISFNVELTFVFTSLVLLSATQGSTILSGWALTLLSNLSYASTCQTIGLTTGYFASFTVFLALNSETFCDKWGIPQLTLSTYLKFCGFAVTFWLIFFQKETYKTIWNICKLPHIRSLIVVHCLGKLAFQANESVTQLKMIEKG-LGREDLAITVLIDFPFQIIGGWLAANWSRLRPWIIAFWPRLALALVQSFASNV--QFVGISAFHTRI--SDPLIGGTYMTLLNTFSNFGGTWPKYFILVDLMSESVCICMTFGVIFV Copci RSMVLLCVLYLIQGVPLGLALGSVPFLLKLTYSQLATFAL-SSYPYSLKLLWSPIVDSIFRIGRRKSWIIPMQLIVGSLMLYISLNVELTTIFTMLVTFSATQ-DIAVDGWALTLLSCLSYASTCQTIGLNTGFFASFTVFLAFNSETFAAKWGIPQLTISAYLRFWAYIVTIWLIFFKKETYQTIWTICQLRHVQLLILIHLFAKIGFVAHE-ATSLKLVEKG-LKREDLSLAVLVDFPFQILGGYFAAKWSRLRPWLYAFWPRFLFGLISSFTSTV--QFVGISAFHTRV--SDPLIGGTYMTLLNTFTNLGGTWPKWFVLVDWFSVGHCICMGFGILFL Croqu1 KAMVLLVVLYMLQGIPVGLAFGSIPFLLRLSYSQIGLFSL-ASYPYSLKLFWSPIVDSCYRIGRRKSWIIPVQALVGMMLWWLGNNVTLTALFFTLVLFAATQ-DIAVDGWALELLSNLSYASTAQTVGLNIGYFLSFTVFLAFNSLEFSNNRDYPIMTLSGYLKFGGLLVTGYLTLIQTEVYHIMFEICQLKHVQSFILLHLIAKLGTSVNDAATSLKLLEKG-LSKEDMALSVLIDFPFQIFLGYFAAKWSSLRPWIVAMWFRLLFAAWSSFASTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKYFVLIDFFTDATCVCIIVGAVIL CryneH991 EA---------LQGVPLGLTFGTLPFLLKLSYSQLAIFAL-STWPYSLKLLWSPIVDAWFKWGRRKSWIVPVQGLVGLGMWVIGGKIFLTAVFGSLILAAATQ-DIAVDGWALTLLSNLSYASTAQTIGIGIGNALSFTVFLAFNSIDFSNKYDYPLVSLGGYMRFWAVGVTVGLAVLKKEVYKVMWSIVRLKNIQTFLFVHLICKIGFQVNDSVTSLKLLEKG-LSKEDLAVAVLLDFPAQMAVGWLAAKWSRLKPWLYAFWARLAMAAISSLTSTV--QFVGICAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKPLILVDMLTVATCVCVTLGAGLL Crypa2 RNFGLLVLLYFLQGVPLGLATGSVPFLLKMSYSEIGVFSL-ASYPYSLKLLWSPVVDAIWKLGRRKSWILPIQLLSGIGMLWLGSMVNFTGWWFFLVLMCATQ-DIAVDGWALTLLTNVSYASTAQTVGLTAGQFLSYTVFLAFNSKDFANRYDVGLISLGGYLNMAGIIVTIGLATMKKEVYKIMWGVLKLKSVQTIMIVHLIAKIGFQANDGVTNLKLLDKG-FGTDNMALTVLIDFPFEIGLGYYAGVWSQMRLWCWGFVGRLVAAVFSTFMNTI--MFVAVSAFHARI--SDPVIGGTYMTLLATVSNLGGTFPRFFVLVDSFTSATCLCVAIGVLTF Debha1 PAFIVLVILYLLQGIPVGLAFGSIPFILKLSYSQVGIFSL-AAYPYSLKLLWSPIVDALYTIGRRRSWIIPIQTISGITLIYLGLKITITMCFFLLVFFCATQ-DIAVDGWALTCLSCLSYASTAQTIGINTGYFSSFTIFLALSSPDFANKYNEGLFSLGVYLNFWGLIVTGALFLIPEDVYNSMYQVLKLPNVQTFVVILLIAKFGFQASESATNLKLLEKG-LSKEDLSITVLIDFPFEMVFGYYAGRWSNLKPWLFGFAGRLFGAFLSSFMSTI--QFVSLCAFHTKI--ADPAIGGTYMTTLNTLSNYGGTWPKLIVLIDKLTIAKCFCIVCGIFIL Dekbr2 PRFVLLVILYMIQGIPIGLAFGSVPFLLKLSYSQVGIFSL-ATYPYAMKLLWSPLVDSIYRIGRRRSWIIPIQVLSGFCLLSMGWKIKLAWWFFILIFFCATQ-DIAVDGWALTILSALSYASTAQTVGINIGYFLSFTIFLAFNSPNFANKYTEGVITLGQYMRSAGLVVTFIIALLVPEVYRRMFSVIKLRNVRTFICLLLVCKIAFQANEGATDLKLLDKG-FSREDLAITVLIDFPFEIIFGYYVARWSSLKPWLYGYLGRIAAALLSSFMSTV--QFVCISAFHTKI--ADPAIGGTYMTTLNTLSNMGGQWPKIIVLIDKFSKATCLCIVLGLVLY Dicdi NNIVWLVLLYLIQGIPIGLSFGTIPFLLHATYTQIGIFTI-STYPYSLKLLWSPIVDSYFSFGRRKSWIVPIQILAGIVFITISFFIYITIVFFLLIFLMATQ-DIAVDAWALTILSYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFEEGIITLPGYLQFWGIILSIYLAFFKDEVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKG-LRKEDIASFSLIQFPSIIIFSIISSKWVKLTIWSNAYLVGVFFILVSSFSYNL--MSVSQGSFFLKI--SDKSIGGTYVTLLNTIANFAGTYPKLFILIDKLTTSECGAIIYGVFIY Dmel RNIAILLFLYVLQGIPIGLI-AAIPMLLQASYKQQAEFSF-AYWPFSLKLLWAPIVDSLYRFGRRKSWLVPVQYLLGAFMLLLSLHVLLTLLFFLLNFLAATQ-DIAVDGWALTMLKNVGYASTCNSVGQTAGYFLGYVVFIALESKDFCNTYEDGMITLPRFLWFWGVVATTLVAIFKKESYKILWDMVCMRPVQILAVILLTVKVTFAASDAVTSLKLIDAG-VPKDKLALLAIPLIPLQLILPLAVGRYTNMDVYLKAIPYRIIMATVYQVFLYS--MFVAAMAFFAKI--SDPAVGGTYMTFLNTLCNLGGNWPNTVVLVDVLTWKQCICVLYGIVWL Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ASFWLLVLLYTIQGVPLGIVLQSIPFLLLTDFAALSIYAA-ASYPYSLKLFWSPIVDSVFAVGRRKSWILPAQACVAIFLFVLSRYIPLTLVAVVIVTAAATQ-DVAVDGWALSLLSTLAYAALAQTIGLQTGSFAGYTIFFALRSASFSDTYTQGITDLEGYLGFWALIMTLVVAIW---TYRQIWNITKSPNMRHLLLFLLLARFAH-APEGTMSARLVSRGDIATTRFATAAVVHFPAQLLASWWAARWCSLDLYMRAYSAKLVLIPIGSVATSV--QFSAQAIYFGRI--ADPAIGGTFLTLLNTFSNLGGTIPNTLFTLQRLTGTRQLAAALGVWLL Fomme1 RGMALLIVLYLIQGVPLGLALGSVPFLLRLSYSQLGKFAL-AGYPYSLKLLWSPIVDSCYTIGRRKSWIIPMQLVIGTLMFWMSNNVKLTFIFTALVLLSATQ-DIAVDGWALTLLSNISYASTCQTIGLNTGYFASFTVFLALNSEAFAARWGVPVLTLSGYLKFWTYAVTLWLVFVKKEVYKLIWSICKLPHVQSLLIMHFICKVGFQANEAATSLKLVEKG-LGREDLALAVLIDFPCQILLGYLTARWSLLRPWFAAGWVRLGFAALQGVSVTI--QFVGISAFHTRI--SDPLIGGTYMTLLNTFTNLGGTWPRYFVLVDFFTIATCVCVTLGILIL Fusgr1 RSFLLLVLLYFLQGIPMGLATGSVPFLLKMSYSEIGVFSL-ASYPYSLKLLWSPFVDAVWKIGRRKTWIVPIQFLSGFGMVWLGSHVSFMLWWFFLVLMCATQ-DIAVDGWALTLLTNVSYASTAQTVGLTAGHFMSYTVFLAFNAADFANKWDEGLLSLGGYLKFWGIIVTIGLGLLKKEVYRIMWGILKLKNVQTIIIVHLIAKIGFQANDGVTNLKLLDKG-FGKDNMALTVLIDFPFEIGLGYYAGMWSQMRLWCWGFVGRLVAALSSTFTNTI--MFVAVSAFHARV--SDPVIGGTYMTLLAT----------YFVLVDSFTVATCLCVLFGAATF Galma1 RGMVLLCVLYLLQGIPLGLALGSVPFLLKLSYSQLATFAL-SSYPYSLKLLWSPIVDSVFSFGRRKSWIVPMQLIVGSLMIYISLNVELTTVFTMLVTFSATQ-DIAVDGWALTLLSCLSYASTCQTIGLNTGFFASFTVFLAFNSEAFALKWGVPHLTLAGYLRFWSFAVTLWLVIFKKEVYKTIWTICQLKHVQLLIVVHLFAKIGFAANDAATGLKLVEKG-FKREDLALVVLIDFPFQIMGGWLAAKWSRLRPWIYAFWPRLAFGLISSFASTV--QFVGISAFHTRV--SDPLIGGTYMTLLNTFTNMGGTWPKWFVLIDLFSIATCICLVFGVLFL Ganpr1 PNIAILSFLYLLQGIPLGVTLGSLPFLLKLSFSQMAIFSL-AGYPYSLKLLWSPLVDSLFSIGRRKSWVLPVQIVTAAVMWWISSWVLLTISFTFLVMLSATQ-DVAVDGWAIEALANIEYASTAQTLGLNSGYFLSFTVFLALNSPEFCSRYGKGVLQLGSYLRFWSMVATACVSQVRERVYATVLRISKMPNMLVLLALLFICKVPFTLNESVTALKLVELG-VDRDILAAAVLIDFPIQVVVGVLAARWAAWRTWLKAYYGRLFFAGVSSFVSTV--QFVSLGSFFATI--ADPTVGGTYMTLLNTFSNLGGTWAKPIVLVDFLTVSTCASVLLGIALL Gloin1 QNVALLVVLYLLQGIPVGLAFGSVPFLLKLSYSEIGLFSL-ATYPYSLKLIWSPIVDAIYRVGRRKSWIIPIQLLTGSLFYWLGKHVTLTLLFFILIFFSATQ-DIAVDGWALTLLSSLSYASTAQTIGLNTGYFLSFTVFLAFNSAEFSNKYDNGFLSMGSYLTFWSLLVTIWLIFIKGEVYRTIWNICKMPHMRRLIVVLLVAKIGFIANESVTGLKLLEKG-FSKEDLALAVLIDFPIQLLVGYYAARWSNLKPWTIAFYGRLFFAAVSSFMSTV--QFVSISAFFTII--ADPVIGGTYMTLLATFSNFGGTWPRFFVLVDYFTEATCATITIGTILL Hisca1 RNFALLCLLYFLQGVPMGLAAGSVPFLLKLSYGQIGIFSL-ASYPYSLKLLWSPIVDAVWRFRGRKSWITPIQMLSLITMLYLG-------------------------------------------------------------------------------------------AVRKREVYKSMWGVLKLTNIHTLIIVHLIAKIGFQANDAVTSLKLIDQG-FGQENMALVVLIDFPFEIGLGYYAGKWSNMRLWCWAFVARLFAALLSTFMMTV--MFVAISAFHARI--ADPVIGGTYMTLLATVSNLGGTFPKFFILVDLFTNATCICVIIGTITF Klula1 KQFYLLVVLYLLQGIPVGLTFGTIPFILKTSFVTIGLFSM-ATYPYSFKILWSPIVDSWYKVGRRRSWIIPVQFVTGITLLTLGYCIALTSVFLFLVILCSTQ-DIAVDGWALNILSSLSYASTAQTIGLNIGYFMSFTIFLSLSSDEFMQKY----FQLSSYLTFTGLAVTFYVSLFTSEIYRLFIKVMKLPSVQTLAIVHLISKFAFQCNDAATNLKLLEKG-LKREDLAITVLINFPFELLFGFYVARLSRLTPWIIGFIGRLSAAILGSFMSTF--QFVSMSAFHTQV--ADPVIGGTYMTLLNTLSNLGGTWPRLLIMIDFFSKYDCFCIVSGLLIF Lacbi2 RSMVLLCVLYLIQGVPLGLALGSVPFLLKLSYSQLATFAL-SSYPYSLKLLWSPIVDSVFSVGRRKSWIIPMQLIVGTLMLYISLNVELTVIFTLLVLFSATQ-DIAVDGWALTLLSCLSYASTCQTIGLNTGFFASFTVFLAFNSEAFAARWGVPQLSLSGYLRFWSYLVTFWLLFFKKEVYKTIWTICKLKHVQLLILMHLFAKVGFAANEAATSLKMVEKG-FRREDLAIAVLIDFPFQITGGWLAAKWSRLRPWMHAFWPRLLFCLISSFASTV--QFVGISAFHTRV--SDPLIGGTYMTLLNTFTNMGGTWPKWFVLVDLFSVAICICMAFGVVFL Lenti61 QAIVLLIILYLIQGFPLGLALGSIPFILRLSYSELAVFSL-SGYPYSLKLFWSPIVDSVFSIGRRKSWIIPMQLIIGTTMLLISLRAMLSFAFTSLVFFSATQ-DIAVDGWALTLLSNLAYASTCQTIGLNTGYLMSYTVFLALNSEDFANKWGIPRLSLSSYLFFCAFAVTLWL-FFIKEVYVTMWEICKLRHVQILLGVHLLAKIGWQASDAATQLKMVEKG-LGREDLAITVLIDFPFEIIGGWLAGKWARLRAWIYAFWPRLILTLVQSFASTI--QFGGMSAFHTRI--SDPVVGGTYMTLLNTFTNLGGTWPRYFVLVDYFSVATCLCIGFGFLTI Malgl1 HGFMLLVLLYMLQGIPVGLAFGTMPFLLKVGYSQLGIFML-STYPYSLKLLWSPIVDSLFSLGRRKSWIVPIQLIVGITFLVISYQILITLVFFGLIVLAATQ-DIAVDGWALTLLSNVGFASTAQTIGINVGYFMSFTVFLALNSVEACNKYSTPILTFPAYLQLCAILITLWLLFFQKEAYATIWKIGKLRHVQLLLIIHMICKIGYQANDAVTGLKLVERG-LGKEDLAFAVLIDFPFQLLFGYLTATWSKLRPWMISLFFRLFFSVVNSFAGTV--QFVGVSAFHTQI--SDPIIGGTYMTLLNTVSNLGGTWPRYFVLVDYFGVSMCICVTVGLCTL Mellp23 KAMVLLVILYMLQGIPVGLAFGSIPFLLRLSYSQIGLFSL-ASYPYSLKLLWSPIVDSIYKIGRRKSWIIPVQALVGMMLWWLGNNVTLTGLFFTLVLFAATQ-DIAVDGWALELLSNLSYASTAQTVGLNIGYFLSFTVFLAFNSLEFSNNRSYPIMTLSGYLKSGGLIVTIYLTFFQTEVYKIMFEICKLKHVQKFILLHLIAKIGTSVNDAATSLKLLEKG-LSKEDLALSVLIDFPFQIGLGYFAAKWSSLRPWICAMWFRLLFAAWSSFASTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVCNLGGTWPKYFVLVDYFTEAYCVCILIGAISL Mnele FSVCVLMFLYVLQGVPLGLS-SSIPIMIQSGYSQQAAFSI-VSYPFSCKLLWAPLVDCVYKLGRRKSWLVPLQYCIGVAMLYIPSVIVLAGWFCFLTFLAATQ-DIAVDGWALTMLSNVGWASTCNSVGQTVGYFFGYLGFLALESPMFCNLFDVGCVTMESYLRFWGILTTTFVAIFVRETYKSMMKIIRLKSVLVYIGCIFVIKASFAPLDSLTGLKLMEAG-LSKDNLVTLSALLIPLQVLLPLIITKYTNLNTYVGGVFPRIFSGILYSVAATM--MFVSQMMFNARV--SDVKMGGTYMTLLNTLINLSGTLPQTISLVDRVTSSTCVSVKLNDVSC Monbr RSVALLLLLYFLQGVPMGLS-ASVPYLLQADYNQQALFSF-VVYPFSLKLLWAPIVDGLFKFGRRKSWTVPCQILIALVLLGSSSHVTLTILFLLLYTLCATQ-DVAVDGWALTMLSRVDLASICNSVGQSAGYFTSFIFFLLLSSPDACNKYDEPMVTLGSFMNFFGVLTTLGVWFFKRETYQRLLQVCKLSSIQQLAFVILTCRIGFAGVESVTALKLQEFG-VPKEDLASLGPLMFPVSLVVPSLMGYLQTMQLWLRAYPFRVLAAI-SVLAIASTIMFTAQMQFFCKL--SDPLLGGTYMTLLTTLANLGAVWPSTLAL------------------- Morel2 WNFALLVILYLLQGVPVGLTFGSIPFLLKMSYSQIGIFSL-AHYPYSMKFLWSPIVDAVYDLGRRKSWIVPIQLLTGLMFLWLGMHITLTVVFFILIFFCATQ-DIAVDGWALTLLSNLSYASTAQTIGLNTGYFLSFTVFLAFNSSEFSNKYDVGLVPLGGYLKFWALAITLWLIFMKKEVYKIILKIIRLPHMKSFMLVLLSAKIGFIANDAVTALKLLEKG-FSKEDLALAVLIDFPFQIIFGYYAVRWSSLKPWLWAFFAHLACCVITSFTSTV--AFVSMGAFMTVI--ADPVIGGTYMTLLNTLSNFGGTWPRFFVLVDYFTVSTCICVLLGFLSL Mucci2 GNFALLVTLYLLQGIPIGLCFGSIPFLLKLSYSQIAIFSL-SSWPYSLKLLWSPIVDAVYKLGRRKSWIVPIQILTGILFYFLGNNIALTYSFLTTIFFCATQ-DIAVDGWALTLLSSLSYASTAQTIGLNCGYFLSFTVFLSFNSSEFSNKYDLGVLQLGSYMRFWSMVVTAYLVFCKKEVYSTIWKICKLPHMRSYVGVLLVSKIGFICHEAVTSLKLLEKG-FSREDLALSVLLDFPLQIFFGYYAAKWSNLKPWLYAFYGRLACSALSSFMSTV--QFVSISAFMTGI--ADPIIGGTYMTLLNTFSNFGGTWPKFFVLVDYFTVNTCLCVVLGLFML Mydma KNVFILFLLYLLQGIPLGMG-GSIPMILQISYKDQAMFSL-VFWPFSLKLLWAPIVDALFKMGRRKSWLIPVQYLIGIFMLILSLNIFLTVIFFLLNFLAATQ-DIVVDGWALTMLQNVGYGSTCNSVGQTAGYFLGNVILLAFSSPDFCNKYNQGIITIGGFLFVWGFIITSLVWIFKSETYLKLFKIVKLPAVQQIVIVLLTVKVGFAATDAVTGLKLIEAG-VSKETLSFLAVPLVPLQIILPLAISHFTALDLFIKAIPFRLVMGLVHQIALYT--MFVAIMGFFARV--SDPTIGGTYMTMLNTISNLGGRWPETLILVDPLTSKQCICTALGFLWL Neucr2 RNFGLLVLLYFLQGVPLGLATGSVPFLLKLSYAEIGVFSL-ASYPYSLKLLWSPIVDAIWKVGRRKSWILPIQLLSGIGMLYLGSRVGFTWWWFFLVLMCATQ-DIAVDGWALTLLTNVSYASTAQTVGLTAGQFLSYTVFLAFHSKEFANRWDHGLMSLGGYLTFWGIAVTIGLGLMKREVYKIMWGVLNLKNVQTIIIIHLIAKIGFQANDAVTNLKLLDKG-FGTENMALTVLIDFPFEIGLGYYAGKWSQMRLWCWGFMGRLVAAILSTFTNTI--MFVAVSAFHARI--SDPVIGGTYMTLLATVCNLGGTFPRFFVLVDYFTTATCLCVAIGVVTF Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSFIVLLFIAKIGFVTNDAVTSLKLLEKG-FKKEDLSVTVLIDFPLQIIFGYYAAKWSSLKPWMIAFYGRIVAAILSSFMSTV--QFVSIGCFFARI--ADPTVGGTYMTLLNTLSNLGGTWPRPLILVDLLT-------------- Pench1 RNFLLLVLLYFLQGIPMGLATGSVPFLLKLSYGQIGIFSL-ASYPYSLKLFWSPIVDAVWRFGRRKSWITPVQVIAGLAMIYMGGHIKFTYWWFMLVLFCATQ-DIAVDGWAITLMSNISYASTAQTVGLTAGHFLSYTVFLAFNSKDFANRWDGGLLSLGTYLNFWGLIVTCGLAFLKKEVYKSMWSVLKLKNIQTIIVIHLIAKIGFQANDGVTSLKLLDKG-FGQDNMALVVLIDFPFEIMLGYYAGQWSTMRLWGWAFVGRLAAAVLSTFMNTV--MFVSISAFHARI--ADPAIGGTYMTLLATVSNLGGTFPRIFVLVDMFTQATCLCVLIGALTF Phybl2 GNFLLLVILYLLQGIPVGLSFGSIPFLLKMSYSQIAVFSLSSSWPYSLKLIWSPIVDAVYKLGRRKSWIIPIQTLTGILFLWLGSRIYLTFLFLTTIFFCATQ-DIAVDGWALTLLSSLSYASTAQTIGLNTGYFLSFTVFLALNSAEFSNKYDTGLVPLGAYMKFWGFVVTAWLAFVTKEVYETIIKICKLSNVRSFIAVLLVSKIGFICHETVTALKLLEKG-FSKEDLALAVLLDFPLQVLFGYYAAKWSNLKPWLYAFFGRLVCSALSSFMSTV--QFVSISAFMTSI--ADPVIGGTYMTLLNTFSNFGGTWPKFFVLVDYFTVSTCMCVIVGLIML Picst3 PAFFVLVLLYLLQGVPVGLAFGSIPFILKLSYSQVGIFSL-AAYPYSLKLIWSPIVDAVYKLGRRRSWIIPIQTISGVTLIYLGLLITITFCFFMLVFFCATQ-DIAVDGWALTCLSSLSYASTAQTIGINTGYFSSFTIFLALSSPDFANRYDVGLFSLGLYLTFWGLAVTALLWFVPEDVYLAMFKVLKLPNVQTFVIILLISKFGFQVNEAATNLKLLEKG-LSKEDLSITVLIDFPFEMVFGYYAGRWSTLKPWIFGFAGRLVAAALGSFMSTI--QFVSLCAFHTKI--ADPAIGGTYMTTLNTLSNYGGTWPRLILLIDKLTIEECICVIIGIFTL Plicr1 KAMVLLSVLYLIQGVPIGLALGSVPFILRLSYSQLAIFAL-SSYPYSLKLLWSPIVDSVFSIGRRKSWIIPIQFVIGMLMLYISLNVELTVIFTSLVLFSATQ-DIAVDGWALTLLSNLSYASTCQTIGLNTGYFASFTVFLAFNSEAFSKKWGVPVLSLSTYLRFWSFAVTLYLIFVQKEVYKTIWNICKLKHVQSMIIMHFFAKVGFQANESVTSLKMVEKG-LGREDLAITVLIDFPFQIFGGWLAARWSRLRPWVWAFWPRLGFSLIQSFSSTI--QFVGISAFHTRI--SDPLIGGTYMTLMNTFSNLGGTWPKFFILVDLFTVATCVCMTFGVLFL Polpo SNIIWLIVLYLFQGIPVGLAFSTIPFLLHATYTQIDSVVS-VRRQYLLAKVWSAVYLAVS--------------------------------------------DRQSDSDVFSEVS--TFAATNKKIEDH-------------HTHDYQQQL----------------------------IYKSLWKIITLPHIQTLSILFLTCKIVFQSNDAL-SLRLLEKG-MKKEDLASFSIIQFPCTLLFSLISSKMIKLSLWTNAYLLGIIVVSLSSFVSTT--MQVAQGSFFLKI--SDKAIGGTYLTLLNT---------------DYFSKNICALIIYGLFMY Pucgr2 RAMVLLVVLYMLQGIPVGLAFGSIPFLLRLSYSQIGLFSL-ASYPYSLKLLWSPIVDSCYSIGRRKSWIIPVQALVGVTLWWLGDHVTLTVLFFTLVMFAATQ-DIAVDGWALELLSNLSYASTAQTVGLNIGYFLSFTVFLAFNSLEFSNNRDYPLMTLSGYLKFGGILVTLYLSFFQTEVYQIMYEICKLKHVQSFILLHCIAKLGVSVNDAATSLKLLEKG-LSKEDMALSVLIDFPFQIFLGYFAAKWSSLQPWIWAMWFRLAFSAWSSFASTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKYFVLVDFFTEANCICITLGAILL Punst1 RGIVLLIVLYLIQGVPLGLALGSVPFLLRLSYSQLAVFAL-SSYPYSLKLLWSPFVDSKYSVGRRKSWIIPMQAIIGTLMLYISYNVMLTAVFTSLVLFSATQ-DIAVDGWALTLLSNISYASTCQTIGLNSGYFASFTVFLALNSQNFSDKWGIPRLELATYLRFWTYCVTIWLLFFKKEVYKNIWGICKLSNIQTMLIVHLLAKIGFQANEAVTRLKMVEKG-LGREDLAIAVLIDFPFQILGGWLAARLCTLRPWIWAYWPRLGFALSQSFCETL--QFAGISAFHTRI--SDPLIGGTYMTLLNTFSNLGGTWPRFFVLVDFFTVATCICLVLGAISI Rhior3 GNFALLVILYLLQGIPVGLSFGSIPFLLKLSYSQIAVFSL-SSWPYSLKLLWSPIVDALYQLGRRKSWIIPIQILTGVLFYILGNNIVLTYSFLTTIFFCATQ-DIAVDGWALTLLSSLSYASTAQTIGLNCGYFLSFTVFLSFNSAEFSNKYEYGVLGLGDYMRFWAMLVTAYLIFYKKEVYSTIWKICKLAHMKSFIAVLLIAKIGFICHEAVTSLKLLEKG-FSREDLALSVLLDFPLQIFFGYYAAKWSNLKPWLYAFYGRLACSALSSFMSTV--QFVSISAFMTSI--ADPIIGGTYMTLLNTFSNFGGTWPKFFVLVDYFTVNTCLCVLMGLMCL Rhoto1 RALALLVALYLLQGIPVGLAFGSIPFLLRLSYSQIGIFTL-CTYPYSLKLLWSPIVDSLFKLGRRKSWIVPIQTIVGILFWWLGNNVLLTGLFFTLVFFAATQ-DIAVDGWALTLLSNLSYASTAQTIGLNTGYFLSFTVFLAFNSVEFSNKYEYPLISLSGYLHFWAIAVTAYLAFFQPEVYSIMVEICKLKHVQSFMIVHLVTKLGTAANDAATSLKLLEKG-LKKEDLALAVLIDFPFQILFGYLAAKWSKLRPWLIAMWTRLGWAAISSFSSTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKFFVLIDAFSVAVCLCILAGVAVL Rozal11 PSIILLIMLCLMQGIPAGLALGTLPYLLKLTYSDLALFSI-AGYPYSFKILWSPIVDAIF------------------------------------VFLAATQ-DIAVDGWALTILSNLRYASTCQTIGLSSGYFISFTLFLAFNSSEFANLFDYGFIDLGGFSYFWGFFVTLIVLFYKEGSYKTMLKIVKLPNMCLFLLVLLLCKIGFIGVESSIGYKMLDKG-FKKEYTAITVLIDFPFQLVSGYYAAKWTQLKPFLWGGLLRLSLALWVSFTSNV--MFVSMGAFFAQI--SDPVIGGTYMTILNTFSNLGGTWPKFFVLIDYLTKAECVTLAIGGVLF Sacce1 PQFYLLIMLYLAQGIPVGLAFGTVPFLLKTSFTSLGIFSM-ATYPYSLKIIWSPIVDSLYRIGRRRSWIIPVQFVSGFVLWALGWCINLTWWFGLLVFLCATQ-DIAVDGWALTILSSLSYASTAQTIGLNIGYFMSFTIFLSLNSSDFANKYDHGFISLGGYMKFSGIVITIYIIFCTKEIYRCFIKVLKLKSVRSLAFIHMISKFAFQCNEAATNLKLLEQG-FKREDLAVTVLIDLPFEIIFGYYVVKWSSLTPWLWGFLGRLAAAVLGSFMNTV--QFIGISAFHTRV--ADPVLGGTYMTLLNTLSNFGGTWPRLIIMINYFTVYQCICIVVGLFLY Salro LKMALLVLLYTLQGIPMGLA-ASIPLLLQTNYGSQALFSF-TSWPFSLKLLWAPIVDGLFKFGRRKTWLVPAQLLIGLLMLVAAQPIAITAIFFVLYFLCATQ-DIAVDGWALTMLDDVDKASICNSLGQSLGYFTSYLLFIALNDTSVCNKYDEPLVTLGDFFVFFGLVTTIIVAIFKRESYVKLTQLLSLRPVQLLGLFLLTCRLGFVCLESTFALKLQEFG-VPKAEIAALGPLAFPVQLLVPPLMGRFAGLALWTKLYPIRIGLGILSALSQA---MFTLQMQFYCQI--SDPSIGGTYMTFLNTLTNLGGIWPATSSMIGQLT----GTLVIGLLWY Schco3 RSMALLCVLYLIQGVPLGLALGSVPFLLKLSYSQLATFSL-SSYPYSLKLLWSPIVDAVFSIGRRKSWIVPMQMIVGTLMLYISLNVELTFVWTSLVFLSATQ-DIAVDGWALTLLSSLSYASTCQTIGLNTGYFASFTVFLAFNSVDFVNKWGLPQLTLDVYLKFWSYLVTLWLLFFKKEVYKTIWDICKLKHVQQLIFLHFFAKLGFAANEAATSLKMVEKG-FKREDLAVAVLIDFPFQMIGGWYAAKWSRLKPWIIAYWPRLLFCLVGSLASTV--QFVGISAFHTRV--SDPLIGGTYMTLLNTFTNLGGTWPKYFVLIDMFSVSTCLCMAFGVIFL Schpo1 RNIYFLILLYLIQGVPMGLVRGSIPYFLKVSYSDLATYSL-AAYPYSLKVLWSPIVDTYYSFGRRKTWVVPCMLLISSTLLLFSYNVSFTTWSFLLVFVCATQ-DIAVDGWSLNMLNQLSYASTAQTVGLNTGFFLSFTILLVFTSPEFANTFNEGLITLSGYIKFWAFIASVLVCFW---MWKTIRAALSLKNMRQLLIVHTLGKVGFVANETLTLLKATEFG-LSNEMLSLIILINFPLGLALGVYTGRISNLDIWLKGYWGRVVSILLASF-STI--QFVALGVFHSKI--SDPHIGGTYMTILNTLSNLGGSWPQYVMLADLLTVSSCVGIFLAISIC Sorma RNFGLLVLLYFLQGVPLGLATGSVPFLLKLSYAEIGVFSL-ASYPYSLKLLWSPIVDAIWKVGRRKSWILPIQLLSGIGMLYLGSRVSFTWWWFFLVLMCATQ-DIAVDGWALTLLTNVSYASTAQTVGLTAGQFLSYTVFLAFHSKEFANRWDHGLMDLGGYLTFWGIAVTIGLGLIKREVYKIMWGVLNLKNVQTIIIIHLIAKIGFQANDAVTNLKLLDKG-FGTENMALTVLIDFPFEIGLGYYAGKWSQMRLWCWGFMGRLVAAVLSTFTNTI--MFVAVSAFHARI--SDPVIGGTYMTLLATVCNLGGTFPRFFVLVDYFTTATCLCVAVGVVTF Sphar QNIALLVCLYLLQGIPIGLAFGSVPFLLKLSFSDIAIFSF-AQYPYSLKILWSPIVDAVYNIGRRKSWIIPAQVLCGLLFLTIGQSIYFTSIFVLLIICAATQ-DIAVDGWALELLPHREYASTCQTIGLNSGYFLSFTVFLSFNSAEFCNRFELGLLQLGSYMQFWGILVSLWLLVVKKESYS---------------------------------------------------LTGLPLSDISGYL--------------------------------------------------------------------------------MAVCL--------- Spipu1 GNITLLIVLYLLQGVPLGLSFGAVPFLLKLSFADIALFSL-SSYPYSLKLLWSPIVDSVFAIGRRKSWIVPIQALTGTCLAVLGSRIMLAIVFTALVFLCATQ-DIAVDGWALTLLRNKHFASTAQTIGLNTGYFLSFTVFLALNSSEFCNKYTEGVLQLGSYLQFWGLLCDAWLVCFKKEVYQTIWKVCMMPHMKKFIGVLMVAKIGFIANEAVTPLKLLDKG-LHKEDMALSVLIDFPFQILFGYYAAKWSSLRPWLYAFYGRLAFAVVNSFTSTV--QFVGMGSFFTKI--SDPLIGGTYMTLLNTLSNLGGTWPRFFVLVDHYTDAHCTSVIIGLLTL Sporo1 KALGLLVALYLLQGIPVGLAFGSIPFLLRLSYSQIGIFTL-CTYPYSLKLLWSPIVDSIFKLGRRKSWIVPIQTIVGLMFWWLGSNVTLTALFFTLVFFAATQ-DIAVDGWALTLLSNLSYASTAQTIGLNTGYFLSFTVFLAFNSVEFSNKYEYPLVTLSGYLHFWAIAVTAYLAWFQPEVYSIMKEICKLKHVQTFIIVHLVTKLGTAANDAATSLKLLEKG-LKKEDLALAVLIDFPFQILFGYLAAKWSALRPWLLAMWTRLGWAFVSSFSSTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKFFVLIDAFSVAVCLCIASGALIL Stehi1 KAMALLSILYLIQGVPIGLALGSVPFLLRLSYSQLAVFAL-SSYPYSLKLLWSPIVDSIFSVGRRKSWIIPMQLIIGSLMLWISYNVTLTFVFTSLVMIAATQ-DIAVDGWALTLLSNLSYASTCQTIGLNTGYFASFTVFLALNSEAFSQKWGIPQLQLGTYLRFWSFCVTVWLTFFQTEVYKTIWNICKLKHVQTVLLVHLSAKIGFAANEAVTSLKFVEKG-LGKEDLAVAVLIDFPFQIAGGWLAARWSRLRPWLWAFWPRLGFAILQSFSSTI--QFVGMSSFHTRI--SDPVIGGTYMTLLNTFTNLGGTWPKFFVLVDFFTIAKCLCITTGVIFF Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr RAFWLLVLLYAAQGAPLGITMGSLSFLLKFSFSSMGLFSI-AMYPYSLKVLWAPLVDAFFVFGRRKTWIVPMQTISGLIMIALSYYTTLVAVFFVLVVVTATQ-DIAVDGWALTRLANRSYASTCQSIGLNIGFFVSFTVFLALHSPEFCNAYHYGLWTLSGYLFFVGLAVTAVLVLFVTEIYRVFLALAKSRNFLRLVAVLLLVKIGFVADDAITPLKLMEAG-FKTEDLALVAVIAFPFSIVFAMLAGRWASFRLFVVAWLVRIGLVFVSSLASSF--MFVVMCGWFARI--ADPRVGGTILTALNTLSNLGGTWPKPIAMVDMLSIPGLGSALAALAIF Treme1 QAFALLVLLCELQGIPLGLTFGTIPFLLKLSYSQLAIFAL-STWPYSLKLLWSPIVDAWFKWGRRKSWIVPVQAIVGVGLWIIGSRVFLTTVFGSLILAAATQ-DIAVDGWALTLLSNLSYASTAQTIGLGIGNALSFTVFLAFNSPDFSNRYDAGLVSLGGYMKFWGALVTVWLARFKREVYKVMWSIVQLPNIQSFLLVHLICKFGFMVNDSVTPLKLLEKG-LSREDLAVAVLLDFPAQMIAGWLAAKWSRLRPWVYAFWARLGMAGISSLTSTV--QFVGITAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPKPLILVDLLSSSICICVSLGAAVF Trire2 RSFLLLVLLYFLQGIPMGLAMGSVPFLLKMSYGEIGTFSL-ASYPYSLKLFWSPFVDAVWKIGRRKTWIVPIQFLSGFGMLWLGSNVSFMLWWFFLVLMCATQ-DIAVDGWALTLLTNVSYASTAQTVGLTAGHFMSYTVFLALNASDFANKWDDGLVSLGGYLTFWGIIVTIGLGLLKREVYRIMWGILKLRNVQTIIIVHLIAKIGFQANDGVTNLKLLDKG-FGKDNMALTVLIDFPFEIGVGYYAGMWSQMRLWCWGFAGRLLAALISTFTNTI--MFVAISAFHAKV--SDPVIGGTYMTLLATVSNLGGTFPRYFVLVDSFTVATCLCVLFGVATF Umbra1 PNFMLLIVLYLLQGIPVGLSFGSIPFLLKMSYSEIAIFSL-SSWPYSLKLLWSPIVDAIYELGRRKSWIIPIQTLTGILFLALGWHIFITTLFLVTIFFCATQ-DIAVDGWALTLLSSLSYASTAQTIGLNTGYFLSFTVFLALNSAEFSNKYEVGVMPLGTYMIFWSLLITAWLLIVKTEVYHTIWKICKLPHMKSFVTILLVAKIGFICNEGVTALKLLEKG-FSKEDLALAALLDFPFQIVFGYYAAKWSSLRPWLYAFYGRLTCAVLSSFMSTV--QFVSISAFMTSV--ADPLIGGTYMTLLNTFSNFGGTWPKFFVLVDKFTVTTCLCVLLGITLL Ustma22 KAMILLVILYLLQGVPVGLAFGTMPFLLKLSYGDIGFFML-CTYPYSLKLFWSPIVDSTFSLGRRKSWIVPIQAVVGVMFWYLSSNVLITLIFFVLILFAATQ-DIAVDGWALTLLSNLSYASTAQTVGLNSGYFLSFTVFLAFNSVEFSNKYDYPLLSLSSYMRFWALLVTVWLVVFKKEVYSIMWRICQLKHVQTFILIHFVAKIGFQANEAVTGLKLVEKG-FGKEDLALAVLIDFPFQLIFGYLAARWSKLQPWVVAFFFRLGFAVLGSFASTV--QFVGISAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPRYFVLVDLFTISSCLCVVIGTLLL Walse1 SAMIILVILYLLQGVPTGLAFGSIPFLLKLSYSQIGVFSL-STYPYSLKLLWSPIVDACFKLGRRKSWIVPIQFLVGAMMYWMSFWILLTFTFFSLIFLAATQ-DIAVDGWALTLLSNLSFASTAQTIGLNTGYFLSFTVFLALNSVEFSNKYDYPLVTLGGYLQFFGVLFTIWLAFFKKEVYNQMLSILKLKHVQSFVIVHLVAKIGFQANEAVTSLKLLEKG-LSREDLALAVLIDFPVQIIGGWLAARWSQLKPWLGAFVGRLAYAIVGGFMSTV--QFVGICAFHTQI--ADPLIGGTYMTLLNTVSNLGGTWPRYFVLVDGLSIATCLCVVIGTVIL Zygro1 PQFYLLVALYFLQGIPVGLAFGTIPFLLKTSFTTLGIFSI-ATYPYSLKILWSPIVDSIYKVGRRRSWIIPIQLLSGSMLFILGWAVTLAWYFGLLVFLCATQ-DIAVDGWALTILSSLSYASTAQTVGINLGFFLSFTIFISLNSSDFANKYEHGFVSLGGYMKFAGILVTIYVIMFTRETYKCFGRILKLKSVQTLVFIHLTSKLAFQCNEAATNLKLLERG-FKKEDLAVTVLIDVPFEVIFGYYVAKWSSLTPWLWGFLGRLAAAALGSFMNTV--QFVGISAFHTRV--ADPVVGGTYMTLLNTLSNFGGTWPRLIIMINYFTVYECMCVLFGLILY [Cluster1480.fasta_al_trimmed; alignment length = 94] Allma1 DNINQHLALVMKSGKYSLGYKSTLKTLRNGKAKLVIISANCPPLRKSEIEYYAMLSKTFVHHYSGNNIELGTACGKLFRVGVLSITDAGDSDII Ashgo11 ENINQKLALVIKSGKYTLGYKSTIKSLRQGKAKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVTVLDAGDSDIL Aspfu1 DTISSRLALVMKSGKVTLGYKSTIKTLRSGKAKLVLIAANAPPLRKSELEYYAMLAKTPVHHFSGNNIELGTACGKLFRCSTMAILDAGDSDIL Aurde31 ESIASRLALVVKSGKYSLGYKTALKQMRNGKAKLVLIAGNCPPLRKSELEYYAMLSKTSVHHFQGSNVALGTAAGKLFHVGVMTITDPGDSDLL Batde5 ETINSKLALVMKSGKTTLGYKSTLESLRNGKSKLIIISGNCPPLRKSEIEYYAMLSKTNVHHYSGNNIELGTACGKYFRVGSLSILDAGDSDII Botbo1 ESISARLALVVKSGKYTLGYKSALKQMRSGKAKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFSGTNVALGTAAGKLFRVGVMTVSDAGDSDLL Botci1 DSINSRLALVMKSGKVTLGYKSTLKQLRSGKAKLVIIAGNTPPLRKSELEYYSMLSKTQVHHFSGNNIELGTACGKLFRCSTMAVLDAGDSDIL Caeel --------MVMKTGQYVLGYKQTLKSLLNGKAKLVIIANNTPPLRKSEIEYYAMLAKTGVHHYNGNNIELGTACGRLFRVCTLAVTDAGDSDII Canalb1 ENINSKLALTIKSGKYTLGYKSVVKSLRTGKAKLVIIAANTPVLRKSELEYYAMLSKTPVYYFQGGNNELGTVCGKLFRVGTLSILDAGDSDIL Cangl ESINQKLALVVKSGKFTLGYKSTIKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSVLDAGDSDIL Capow EGINTRLALVVKSGKFTLGYKSTLKTLRQGKSKLVILSGNTPSIRKSEIEYYAMLSKTSVHHYSGNNIDLGTACGKYFRVGTMSITDPGDSDII Catan2 DNINQHLALVMRSGKVALGYRSTLKTLRNGKSKLVIISSNCPALRKSEIEYYAMLSKTFVHHYAGNNIELGTACGKLFRVGVLSITDAGDSDII Cioin ENINSRLRLVMKSGKYNLGYRQTLRMLRQGKAKLVILASNCPSLRKSEIEYYAMLAKTGVHHYTGNNIELGTACGKYFRVCTLSITDPGDSDII CocheC53 DSINSRLALVMKSGKVTLGYKSTLKSLRTGKAKLVIIAGNTPPLRKSELEYYAMLSKTSVHHFSGNNIELGTACGKLFRCSVMSILDAGDSDIL Coere1 ESINSRLALVMKSGKSSLGYKSTLKTLRSGKAKLIIISGNTPPLRKSEIEYYAMLAKTSVHHYKGNNVDLGTACGKYYRVGTLSVLDAGDSDIL Conco1 ESINSRLALVMKSGKYNLGFRSTLKSIRQGTAKLVIISGNCPPLRKSEIEYYAMLSKTGVHHYTGNNIELGTACGKYYRVGVLSVTDPGDSDII Conpu1 ESISSRLALVVKSGKYSLGYKSALKQMRNGKAKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVGVMTVSDPGDSDLL Copci ESIASRLALVVKSGKYSLGYKSALKQMRSGKAKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVGVMTVIDQGDSDLL Croqu1 ENINSRLALTIKSGKYTLGYKSTLKSMRSGKAKLILVSGNTPPLRRSEIEYYAMLSKTPVHLYQGSNVALGTASGKLFRVGVMTILDAGDSTIL CryneH991 ESINSKLQLVVKSGKFTLGYKQALKQLRSGKAKLILISKNCPPLRKSEIEYYAMLSKTNVHHYDGSNVDLGTAAGKLYRVGVMSIQDAGDSDLL Crypa2 DTLNSRLALVMKSGKVTLGYKSTLKALRSGKAKLVLISGNTPPLRKSELEYYSMLSKAPVHHYGGTNIELGTACGKLFRCSTMAVLDAGDSDIL Debha1 DNINAKLGLVIKSGKYTLGYKSAVKSLRTGKAKLIIIAGNTPVLRKSELEYYAMLSKTQVYYFQGGNNELGTVCGKLFRVGTLAILDAGDSDIL Dekbr2 DTMNAKLALAIKSGKYTLGYKSTVKALRKGKSKLVIIAGNTPVLRKSELEYYAMLSKTPIYYFQGGNNELGTACGKLFRVSTLAVLDAGDSDIL Dicdi ENIGSKLALVMKSGKSQLGYKSTLKTLRAGKSKLILLASNLPSIRRSEIEYYAMLSKTTVHLYSGNNVDLGTALGRHYRVSVMSITDAGDSDIL Dmel ESTNARLALVMKSGKYCLGYKQTLKTLRQGKAKLVLIASNTPALRKSEIEYYAMLAKTEVQHYSGTNIELGTACGKYFRVCTLSITDPGDSDII Enthi EGVNSKLALVTKSGKYVLGTKATLKTIRDGKSKLVIISSNCPPLERAKIEYYAVLGKVQVVHYSGSNVDLGTACGRYFSVSVLSIIDGGDSDIL Falba DSLTSQLNLVMKSGKYSIGHKSTVKTLRTGKAKLLLIASNCPPLRRSELEYIAMLSKTNVHHFPGNNIELGTACGKFFRVSVMSITDAGDSDII Fomme1 ESIASRLALVVKSGKYTLGYKSALKQMCSGKAKLVLISGNCPPLRKSELEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVSVMTISDQGDSDLL Fusgr1 NSINSKLALVMKSGKVTLGYKSTLKSLRSGKAKLIIIAGNTPPLRKSELEYYSMLSKAPIHHFSGNNIELGTACGKLFRCSTMAILDAGDSDIL Galma1 -----MCSLCV--------------------AKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFAGTNVGLGTAAGKLFRVGVMTVSDQGDSDLL Ganpr1 ESINSRLALVMKSGKYTLGYKSTLKTLRQGKSKLVIISGNCPPLRKSELEYYAMLSKTGVHHYSGNNIDLGTACGRYFRVGVLSIMDAGDSDIT Gloin1 ESINTRLALVMKSGKYTLGYKSTLKTLRLGKAKLVIISGNCPPLRKHELEYYAMLSKTPVHHYSGNNIDLGTACGKYFRVGVLSITDPGDSDIL Hisca1 DNINSRLALVMKSGKVTLGYKSTLKSLRSGKAKLVIIAGNTPPLRKSELEYYSMLSKTSVHHFSGNNIELGTACGKLFRCSTMAILDAGDSDIL Klula1 ENINQKLALVVKSGKYSLGYKSTVKSLRQGKAKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVTILDAGDSDIL Lacbi2 ESIAARLALVVKSGKYTLGHKSALKQMRSGKAKLVLIAGNCPPLRKSELEYYAMLSKTSVHHFAGTNVALGTAAGKLFRVGVMTVSDQGDSDLL Lenti61 ESIASRLALVVKSGKYSLGYKSALKQMRSGKAKLVLIAGNCPPLRKSELEYYAMLSKTSVHHFAGTNVALGTAAGKLFRVGVMTVTDPGDSDLL Malgl1 DNINSKLQLVMKSGKVSLGLKSALKNMRSGKAKLIVISANTPPLRKSEIEYYAMLSKTGVHHYQGSNIALGTAAGKLFRVGYV-------SEFV Mellp23 ENINSRLALTIKSGKYTLGYKSTLKTMRSGKAKLVLVSGNTPPLRRSEIEYYAMLSKTPVHLYQGSNVALGTASGKLFRVGVMTILDAGDSTIL Mnele ESINSRLALVMKSGKFTIGYRSTLKSIRQGKSKLIIIANNTPALRKSEIEYYCMLAKVGVHHYSGSNIDLGTACGKYFRVGCLCITDPGDSDII Monbr ESINQKLALVMKSGKYVLGYKSTLKALRSGKAKLVILASNTPPLRKSEIEYYALLSRSLVEHYKGDNIALGTACGKYFRVCTMAITDAGDSDII Morel2 EGINSRLALVMKSGKYQLGYKSTLKTLRQGKSKLVILSGNCPPLRKSEIEYYAMLSKTGVHHYTGTNVELGTACGKYFRVGVLSITDAGDSDII Mucci2 ESINSRLQLVTKSGKYTLGYKTTLKTVRQGKAKLIIIAGNCPPLRKSEIEYYAMLSKTGVHHYNGNNIDLGTACGKLFRTSVLSITDAGDSDIL Mydma ESINSRLALVMKSGKFTLGYRSTLKTLRQGKSKLVIIGSNTPQLRKSEIEYYAMLSKTGVHHYSGNNIELGTACGKYFRVGVLSITDPGDSDII Neucr2 QSIGAKLALVIKSGKVVLGYRSTLKALRSGKAKLILISANTPPLRKSELEYYSMMSKTAVHHYTGTNIELGTACGKLFRCSTMAILDAGDSDIL Orpsp11 ESINSRLALVMKSGKYSLGYKQTLKTLRQGKSKLVIISGNCPPLRKSELEYYAMLSKTGVHHYNGNNIDLGTACGKYFRVGVLSITDAGDSDII Pench1 DTLSSRLALVMKSGKVTMGTKSTMKTLRSGKAKLVLISGNCPPLRKSELEYYAMLAKTPVHHFNGNNIELGTACGKLFRCSAMAILDAGDSDIL Phybl2 DTIGSRLQLVTKSGKYTLGYKSTLKTLRQGKAKLVIIAGNCPPLRKSEIEYYAMLSKTGVHHYNGNNIDLGTACGKLFRASVLSITDAGDSDIL Picst3 ENINAKLGLVIKSGKYTLGYKSVVKSLRTGKAKLVIIAGNTPVLRKSELEYYAMLSKTPVYYFQGGNNELGTVCGKLFRVGTLSVLDAGDSDIL Plicr1 --------------------------MRNGKAKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFSGTNVALGTAAGKLFRVGVMTISDQGDSDLL Polpo ENIGAKLALVMKSGKSQLGYKSTLKTLRSGKSKLILISNNCPPLRRSEIEYYAMLSKTNVHLFNGNNIDLGTGCGKKFRVSVMSITNEGDSDIL Pucgr2 ENINSRLALTIKSGKYLLGYKSTLKSMRSGKAKLVLISGNTPPLRRSEIEYYAMLSKTPVHLYQGSNVALGTASGKLFRVGILTILDAGDSTIL Punst1 ESIAARLALVVKSGKYTLGYKSALKQMRNGKAKLVLIAGNCPPLRKSELEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVGVMTISDQGDSDLL Rhior3 ESINSRLQLVTKSGKYTLGYKSSLKTIRQGKAKLIIIAGNCPPLRKSEIEYYAMLSKTGVHHYNGNNIDLGTACGKLFRTSVLSITDAGDSDIL Rhoto1 DNINARLALVIKSGKYSLGYKSTLKAMRSGKAKLVLISGNTPPLRRSELEYYAMLSKTPVHLYQGSNVALGTAAGKLFRVGVMSVEDAGDSDLL Rozal11 ESINSKLALVVKSGKYTLGVKSTLSSIRNNKAKLIILSSNTPALRKSEIEYYAMLSKTPVHHYSGNNIDLGTACGKFFRVGVMSITDPGDSDII Sacce1 ESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDIL Salro DNLNTKLALAIKSGKYVLGYKQTRKMLRLGKAQLVIIASNAPALRKSELEYYALLSKSLVEHFKGDNIELGTAVGRYHRVGVLTITDPGDSDIV Schco3 ESISAKLALVVKSGKYSLGYKSALKQMRNGKAKLILIAGNAPPLRKSEIEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVGVMTITDQGDSDIL Schpo1 DTINAKLALTMKSGKYVLGYKSTLKTLRSGKAKLILIAGNCPPLRKSELEYYAMLSKANVHHYAGTNIDLGTACGKLFRVGVLAITDAGDSDIL Sorma QSIGAKLALVIKSGKVVLGYRSTLKALRTGKAKLILISANTPPLRKSELEYYSMMSKTAVHHYTGTNIELGTACGKLFRCSTMAILDAGDSDIL Sphar DSLNQRLGLVMKSGKYTLGYKSTLKTLRSGKSKLIIISSNCPAVRKSEIEYYAMLSKTGIHHYHGTNIDLGTACGKYYRCSVLSITDAGDSDII Spipu1 ESINSRLALVMKSGKYTLGYKSTLKTLRQGKSKLIIIAGNCPPLRKSELEYYAMLSKTGVHHYSGNNIDLGTACGKYFRVGVLSIIDAGDSDII Sporo1 DNINSKLALVIKSGKYALGYKSTLKAMRSGKSKLVLISGNTPPLRRSELEYYAMLSKTPVHLYQGSNVALGTAAGKLFRVGVLSIQDAGDSDLL Stehi1 ESIATRLALVVKSGKYSLGYKSALKQMRNGKAKLILIAGNAPPLRKSEIEYYAMLSKTTVHHFAGTNVALGTAAGKLFRVGVMTITDPGDSDLL Tapde11 ---------------------------------------------------------------------------------------------- Thetr ESINSHLALVMKSGKFCLGYKQTLKALRAGKAKLVLLSSNTPPLVKSELEYYSMLAKTGVHHYDGTNNDLGAACGQYFRVSMMAVIDEGDSDII Treme1 DNINARLQLVVKSGRYSLGIKQALKNLRSGKAKLVLISKNCPPLRKSEIEYYAMLAKCNVHHYEGSNIDLGTAAGKLFRVGVMAIQDAGDSDLV Trire2 NSINSKLALVMKSGKVTLGYKSTLKSLRSGKAKLIIIAGNTPPLRKSELEYYSMLSKAPIHHFAGNNIELGTACGKLFRCSTLAILDAGDSDIL Umbra1 ESINSRLQLVTKSGKYTLGYKTTLKTLRHGKSKLVIIAGNCPPLRKSEIEYYAMLSKTPVHHYNGNNIELGTACGKLFRTSVLSITDQGDSEIL Ustma22 DNINTKLQLVIKSGKVALGLKSALKNMRSGKAKLVLISANTPPLRKSEIEYYAMLSKTAVHHYQGTNVALGTAAGKLFRVGVMTILDAGDSDLL Walse1 EGINSKLQLVVKSGKYTLGYKSALKQLRSGKAKLVLIAGNCPPLRKSELEYFAMLSKTAVHHYSGSNVALGTAAGKLFRVGVLTIQDQGDSDIL Zygro1 ESINQKLALVIKSGKYTLGYKSTVKALRQGKSKLVIVAANTPVLRKSELEYYAMLSKTKVYYFQGGNNELGTAVGKLFRVGVVTILDAGDSDIL [Cluster1516.fasta_al_trimmed; alignment length = 237] Allma1 --GDSAPNGTYTHTLYKLDDQG-RKVQVKRILRIGRDMEVSKRAIEERK-KWAKFGAA-K-HHGPGPDTETTRVDTELPLRL-------NP-QQEEASRKLKD---TAIKCRYCG-GPHWSKECPSKDII-----RYVPPSLRMEM-GR------RMDDTYAVRIANLPEDTTDADLI-ELARPFGHVVRSYLAK-YDDGKGFAFVNFATMDMAERAIAKLHGYGYANLILTCEHSK Ashgo11 -------DGSKTIISFKI-DGG-KKLKITQRVKEIKITEKVNKSIAERR-KWAKYGAE-A-GSGPGPNLSTTKLAEELQLRL--APSLKRE-QDEKEKQEE-K---SLYVCRTCGIPGHFTTKCPFRDIL-----KYVPPSRRDVY-KD----QRERDDAMTLKIMQLNENADEMTIKQKLLSPFPNVPRVAVVRNKETGRGIAYVTFASEKDAETALRLLHGRGFMNLILQVDWSK Aspfu1 W-ADDEEDGTKTVVSYRFNDEG-KKVKVTRRIKTTVVREHVNPQVAERR-SWAKFGLE-K-GHAAGPSFDTTSVGENIVFRP--SVNWRQA-AEGSIKDQLKD---KKVKCRICS-GEHFTARCPFKDTM-----SYVPPHLRERM-AGKY----EKDDLATLRVTNVSELAEESELR-DLFERFGRVTRVFLARDRETQKGFAFISFADRTDAARACEKMDGFGYRHLILRVEFAK Aurde31 W-ADDMDNGVRTIVEYYKNDEG-KTVKVTKKIKRVLQKVIVNHTVAERK-QWAKFGAE-K-GNKPGPDRATTTIGEEIPLKI--SAGNKAE-PEAKVQKI------SKISCRICH-GEHYTAKCPYKDSLGGPPAKYVPPSMRESM-YR-PGGN--RDDLPTLRVTNVSEDTTDNDLR-DLFSRFGRVARVYIGRDRETGKGYAFVSFEEKAVAERAMQKVHGMGYDNLILNCQWSQ Batde5 T-EDWLDDGTHVVTTYSFNDDG-KKVKTVKRIRMKLVKAKVNHAVAERK-KWKKFGES-A-GLPAGPDPGSTSLGEKVFLKL--SMTSK-----EQEKKTVKPVGSLTINCRICK-GDHYTTRCPYKDTF-----KYIPPSQRESI-GTGTRMDGRKDDTDTVRMSNLSEDATEQDVR-DLVAKYGTPARVRVVTDYNTHKGFAFISFYDRSTAERVIQKLDGHPYDNLILSVDWSK Botbo1 W-ADDVDNGIRTIVEYTTNEEG-KKVKITRRIKRTLQRSLVEHAVAERK-QWAKFGAE-K-GKKSGPDRATTAIGENVGLKL--SAGNKAE-PETEIKAQL---GGKKILCRLCK-GDHFTSKCPHRDVLAADPTKYVPPSMRESM--R-GTGN--REDLPTLRVTNVSEDTTEDDLR-DLFGKVGRVARVYIGRDRETGKGFAFVSYEDRATGQKAIDKINGLGYDSLILSVQWSQ Botci1 W-ADDEDDGTQTIVTWRFNDDG-KKVKTTRRIRFTKVKEIVNPRVAERK-SWGKFGLS-Q-KDAAGPASDTTSVGENIIFRP--STNWRDA-KEGAMKNKLKD---KQVKCRICS-GEHFTAKCPFKGTM-----SYVPPHLRERMGGGKF----ERDDLATLRVTNVSEMAEEQELR-DMFERFGRVTRVFLAKDRETGKGFAFISFQERSDAAKACEKMDGYGFKHLILRVEFAK Caeel W-AEAVEDGTRTETAFTEVD-G-VRWKVVTQFK--VINKRVPKVVADRK-KWVKFGSC-K-GEPAGPQVATTYVAEEVDMQF--TRNRA---EQQTAKTT------SREHCRHCKGNDHWSTHCPYKVMY-----------MRRQI-------DRNRSDENTCRVTNLPQEMNEDELR-DLFGKIGRVIRIFIARDKVTGKGFAFVTFESRDDAARAIAELNDIRMYHMVLKVEWTR Canalb1 W-ADAGDDGTKTVITFRTNQDG-KKVKITQKIKEVKVQEKVHPLIAQRK-NWKKYGKE-K-NSPPGPDTSTTQLGEKVDLKL--GTSWKEK-KEAHERAQIAV---QTIKCRVCG-GDHYTAKCPFKDTL-----KYVPRHLRE-----------ARDDSTTLKVSQLNSFVDEDMLRNELFAKFGPLQRVTIVRNRETGRGFAYVSFATEEIAQRALDTFNGKGYHSLILHLEWSK Cangl -------DGTKSIITYKT-ENG-EKYKIIQKVRDVKITERVHRSVAERR-SWAKFGAE-K-NSPPGPNNSTTQFGETVELLL--DRNWRIE-ARKAS-AS------KTITCRLCG-NAHYTMNCPFKTIL------YVPPSRRDAY-RD----ARERDDSCTLKILQLNENADENTLRNELLFPFEPIQKVVVVRNKETGRGLAFVTFINEDMAEKALHFLDGRGFMNLILRVDWSK Capow W-GDVLDNGVKLVIEHRRDDNG-AVVKVTRKFQLSKQKTTLSHAEAERR-HWTKFGAE-T-GAKPGPDPATTIVADEVFLVL--TAKSHDA-TSEKIKLAGGAVASKAVSCRICK-GDHWTTHCPHKELA-----KYVPPSMRSSM-------RD-RDDANTIRISNLSDDTRESDVG-DLCSPFGRVQRTFLVRDKVTGKGFAFVSFGSRDEAAKAIEKLHGHGYDHLILSVDWAK Catan2 -----------------------------------------------------------------------------------------HP-DEQTAQRALKD---STIKCRFCG-GPHWSKECPSKDII-----RYVPPSVRRMM-PR------RMDDSFPVRIANLPEEMSDQDLV-DLAQPFGRIARSYLAK-HDDGKGFAFVNFSTYTEAEAAVSRLNGYGYANLILTCEHSK Cioin W-ADQVE-DIKTVVEYKYNEDD-KKVKVVRKYRIET--QKTSKSVAHRK-LLKKFGKS-S-NDLSGPNRATTIISEDVQMQF--VSTREQE-QESKFKHQFK----------------NFKATAP-KDKT-----KYVPPSMRSSM----PSGRGNRDEQATIRVTNLSEETKESDLQ-ELFKPFGPLQRIYLAKDKHTQKGFAFINFYNRDDAAKAIKSVCGFGYDHLILNVEWAK CocheC53 W-AEEDDDGTETVISYRIED-G-KKIKTTRRIKKTVVKQVVNPRVAERK-QWAKFGQE-K-GKPPGPQTDTVSVAENIVFRP--VSNWKST-EDAKKKAELKN---AKIKCRICQ-GDHFTTKCPFKDTM-----GYVPPHLREKM-GGKF----DRDDSATLRVTNVSEFAEEQDLR-DMFSRYGHVTRVFLAKDRETGKGFAFVSYADRSDAAKACEKMDGFGFGHLILRVEFAK Coere1 W-ADEVDDGSRTLIEYRLNEDG-KKVKSTRRIKNKVVQEHVNRAVAERK-KWAKFGAE-R-GAAPGPNISTTTVGEVILLRL-SQYAAQKQ-QEQKEQEKLAA-KSSRILCRNCR-GEHFTARCPYKDTLNAEPGSYVPPHMRDSM-HE------RRDENPTIRITNLSENTQDDDVK-QLCRSFGPIARAYVAIDRMTQKGFAFVSFYDHDSATEAIAKLNGHGFDHLILNVEWAN Conco1 W-ADEIGNGLTVVVEYRENEDG-KKVKITRKIQKILKKERVNHAVAERK-KWAKFGDE-K-GNKPGPDTKTTSVGEVINLKLALNVAGEE----AKLKESLKG---RKILCRICK-GDHFTTKCPYKDTL-----KYIPAHRRDSP-R-----D-RRDDSITLRVTNISEDARESDIH-ALFRKFGQLTRVFVAKDHDTGKGYAFVSFDRRDEAQKALEHLNGFGYDNLILRVEWAK Conpu1 W-ADDVDNGVRITVEYSVNDDG-KKVKITRKTKRVLQKAVVEHAVAERK-KWAKFGQE-R-GNKDGPDPATTTVGENVYLKL--SAGNKNE-PEQSIKGQLQKAGAGKVVCRLCK-GDHFTAKCPYKDSLGAFPAKYVPPSMREAM-GR-PGRG---DDLPTLRVTNISEDTQENDLR-DLFGRFGRVARVYVGRDRETGKGFAFVSFEERAVAQKAMEKVHGMGYDNLILSVQWSQ Copci W-ADDVDNGVITTIEYAINDEG-KKVKITKKIKRTLQKSVVDLTVAERQ-KWAKFGQE-R-GNKPGPDRATTTVGENVTLKI--SAGNKSE-QEDTVKAKLKTAGAGKVTCRLCK-GDHFTAKCPFKDKLGAEPAKYVPPSMRERM-GG-S-----REDLPTLRVTNISEDTAENDLR-ELFGVFGRVARVYVGRDRETGKGFAFVSFEDRAVAQRAMEKVNGRGYDNLILSVQWSQ Croqu1 W-ADELDTGIKTIIEIKFNEAG-KKIKTIRKIKRTLITTQVSHSVAIRK-QWSKFGAE-L-GKKSGPDSSTTTLGEAVKIKL--IAGGI---KEPTKVTNNTG-VSRRITCRLCQ-GDHFTASCPYKETLAVNQSKYVPPSQRDSM-QQ-KSNN--RDDLPTLRVTNLSEDVQESDLW-DLFARFGRISRIYVGKDQETGKGFAFVSFEDRNEAEKAMKKINGLPYDHLILGCMWSL CryneH991 WAADDVDDGITTIVSWKYNADD-QKVKVTRRVRRRLQVSTVTQTMAERK-QWPKFGLD-K-GKPPGPDRKTTIIGENLHFKI-------SK-IQTAAKAP----TGKAVVCRLCS-GQHYTARCPFREQL-----KYVPPSQRESM-FR------ARDELPTLRVTSLSLDAEEDDLR-ALFQPFGKLGRANIVRDRNTRKGLAFVSFESKRDAEAAMAHLNGRGYDSLILEVAWSQ Crypa2 W-ADDDDDGTKTVISYRIDDQG-RTIKTTRRIRMITHREVVNPLVAMRK-KWPKFGLS-A-NDGAGPAPDTTSVGENIIFRP--SANWKEA-QNQSLKQKLAG---SKVKCRICN-GEHFTARCPYKDTM-----SYVPPALREKM-GGKYS---DRDDFATLRVTNVSEMAEEQELR-DMFERFGRVTRVFLAKDRETGKGFAFISFADRDDAVKACNKMDGFGFKHLILKVEFAK Debha1 W-ADAEDDGTKTVVSYRLNANG-QKVKITQKIKEVKVKEKVHPLIAQRK-NWAKYGKE-K-NTPPGPDTRTTQLGEKVELKL--GTSWKEK-QEEEQKAQVST---QRIKCRTCG-GDHFTSKCPFKDTL-----KYVPRHLRDL---------KDRDDSTTLKISQLNSIVDEDMLRNELLGRYGPFQRAIVVRNRETGRGFAYVTFATESKAEEALNDLNGKGYHSLILHLEWSK Dekbr2 W-ADAENDGTKTVISYKFDDKH-RKVKVTQKIKTVKVTETVNPAIAERK-KWTRFGDE-KDNKIVGPDTRTTQFGEEIKFHL--SASSKEE-EEAKESTTV-----QTLKCRTCG-GNHFTSKCPFKDTL-----SYVPPHLRSE---------AQKEVTTTVRVTNLNTMLSEDLLR-EIFSRFGYVQRLTILRNRETGRGIAFVEMDTVEHAKSAIEKLNGRGIMNLIINADFAK Dicdi ----------EKTIEVIVKNDG-EEVKVIKRYQEYQITVKRNRKVDERK-KWKKFGEC---DNKTG--LENTAYGDEQFLVL--TRGAEEE-EK------------DVVKCRICK-KNHFTTKCPYKDAL-----KYIAPNLR-------------GSDVPSIMVSNLSQNATEKDLY-ELFGQFGPVSRVSIPKSME-GKGFAYVTYNHLDSAEKALKQLNGHRYDYLVLSLEFAK Dmel W-ADEVENGQKYVTEYKYNKDD-KKTKVVRTYK--ISKQVVPKTVAKRR-TWTKFGDS-K-NDKPGPNSQTTMVSEEIIMQF------------EKANDPLDP-TKNIAKCRICN-GEHWSVNCPYKGTA-----KYVPPFLK----------MRGRDDTAAIRISNLSESMTEADLE-ELVKKIGPQSKMYLARDKNTGKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSK Enthi -------EGLSVLTEFPKEEEG-DEIIIKRIYA-------ISENVERRK-NIQKFTKL-E----------VPSDSEDIVLVF-PSQIAQAE-QEEVKKSE------EDVICSGCGEKGHFFFNCPHKDSR-----IYVPVHMR------------DYNPDVSIRLSNIPASVDETVIK-ALYHKVKEILRIFFPKDYVTGRDYCFINVSTKEIAQNAISKLDGYLLEYAKLACAISK Falba W-------------------------------------------------KWRKFGRA-A-NHPPGPQFSTTGLGEPITFRMQLSTRVE---EERSMVDSLRT--NDGVSCRICR-GSHFTAVCPHRDNL-----RYVPPIMR------------NEPPAYTIRVSNLSEFMYEDALR-TLFAKCGIITRIFLATDRQGNKGYAFVSYLNKADAERAIQEYNKYGLDNLIMEVDWAR Fomme1 W-ADEVDNGIITVVEYSVNDEG-KKVKITKRIRRTVQKTVVQHAVAERK-NWAKFGQE-K-GNKPGPDRATTTVGENVVLKI--SAGNKSE-PEENIRASLAKAGAGAVRCRICK-RDHFTARCPLKDSF-----KYVPPSMREAM-GR-IGGS--RDDLPTLRVTNVSDDTTDQDLR-ELFSVFGRVVRVFVGKDRETGKGFAFVSFEDRAVAEVAMGKMHGWGYDSLILNVQWAK Fusgr1 W-ADDDDDGTKTIITFRYDDDG-RKVKTVRRVRFITHTETVNPRVADRK-TWPKFGLS-A-KDPPGPAPDTTSVGENIIFRP--SVNWRAE-KDQTMKDQLKD---KQVKCRICN-GQHFTARCPYKDTM-----SYVPPALRERM-GSKFG---ERDDFATLRVTNVSEMAEEAELR-DMFERFGRVTRVFLAKDRETGKGFAFISFADRGDAVKACAKMDGFGFKHLILRVEFAK Galma1 W-ADDVDNGIRTTIEYALNEDG-KKVKITRRIKRTLQKSVVDHAVAERQ-KWAKFGQE-K-GSKPGPDRATTTVGENVSLKL--TAGNKSE-AEETMKSRVKAAGAGKVACRLCK-GDHFTAKCPYKDTLGADTSKYVPPSMRESM-RG-A--G-NRDDLPTLRVTNISEDTQENDLR-ELFGGFGRVARVYVGRDRETGKGFAFVSFEEKANAQKAIDKVHGRGYDNLILSVQWSQ Ganpr1 W-ADEEEDEIIEVVFTRKNEAG-KTVKVTQKMKRTLVKTVTNHVVAERK-KWTKFGDA-K-GDRPGPNQSTTVVGEKMDLKM-------NV-DNGGDKKLLTK---APLKCRICK-GAHFTARCPYKDSM-----KYVPPSLRESMMMR------PRDEYPTLRVSNLTEDATEEDMS-QLFKRFGRLQRCFVAKDRETGKGFAFISFYSHEDAQKAIDKVNGYGYDNLILKVEFAE Gloin1 W-ADEVGNGVKTIIEYKTNDDG-KKVKVTRKIKKTLITERVNKVAAERK-KWAKFGDE-R-GKKAGPDLSTTSIDQQIFLKL-STTGKHSI-E-NKKKAALIG---KKILCRICK-GDHFTTKCPYKDTL-----KYIPPSMRDSY-K-----E-RRDD-ATIRVTNLSGDTTEGDIH-DLFRRFGGISRVYLARDRETNKGFAFVSFVLRDDAAKALQAINGYGYDNLILRVEWAK Hisca1 W-ADDEEDGTKTVISYRFNDDG-KKVKTSRRIRTTVVKEHVNPRVAERR-GWPKFGLE-K-GHPAGPSFDTTSVGENIIFRP--SVNWKQA-KEGSIKDQLKD---KKVKCRICS-GEHFTAKCPFKDTM-----SYVPPHLRERM-GGKY----ERDDLATLRVTNVSELAEEQEIR-DMFERFGRVTRVFLAKDRETNKGFAFISFQDRSDAARACEKMDGFGYRHLILRVEFAK Klula1 -------DGSKTVISFKI-QDG-KKYKVTQKVKEITVTEKVNKNIALRR-NWKKYGAD-K-GAAPGPDISTTQLGEELELDL--SPNWKEE-EKAANSTQ------KVITCRICG-GAHFTMHCPYKDTL-----RYVPPSLRNAY-QD----QRERDDAKTIRLTQVNELADEEVLKRELLFPFGEIPRVFVVKNPETGRGVAYVTFQTEEIAAQALKLLEGRGFMNFMLHAEWSK Lacbi2 W-ADDVDNGVRTTVEWSVNDEG-KKVKITRRIKRTLQKSVVEHAVAERQ-KWAKFGAE-K-GNKPGPDRATTTVGETVSLKL--SVGNKSE-AEDNVKARVKAPGAGKVSCRLCK-GDHFTAKCPYKDTLSVDPSKYVPPSMRESM-RG-APGS-NRDDLPTLRVTNISEDTQENDLR-ELFGMFGRVARVYVGRDRDTGKGFAFVSFEERAVAQKAMEKVNGKGYDNLILSVQWSQ Lenti61 W-ADDVDNGVRTTIEYTINDEG-KKVKITRKIKRVLQKAVVDHTVAERK-TWAKFGQE-K-GNKPGPDRATTTVGENVWLKL--SPECQAA-KEQTVKANLAKAGAGKVVCRLCK-GDHFTAKCPYKDSLTGTPAKYVPPSMRESM-GR-PGGS--RDDLPTLRVTNISEDTQENDLR-ELFGAFGRVARVYVGRDRETGKGFAFVSFEDKAVAQRAMEKMHGRGYDNLILNIQWSQ Malgl1 ------------------------------------------------------------------------------------------------MREKLAN---KRVQCRLCK-GDHYTARCPYRDTLKMNPVKYKPPSLRHGM-GG-PT---QRDESATLRVTNLSEDVEEEDLR-DLFRRYGRVTRIFVGRDRETGKGFAYVNFE---------------------------- Mellp23 W-ADELDTGTKTIVEVKFNDAG-KKVKIVRKIKRTLVTTSVSHEVAARK-QWSKFGAE-A-GKKPGPDLATTTLGETVKIKL--MAGGV---KEPTKAA-VTG-VSRRITCRLCQ-GDHFTASCPYKETLPPSVAKYVPPSQRDSM-QK-P--N--RDDLPTLRVTNLSEDVQENDLW-DLFARFGKISRIYVGKDQETGKGFAFVSFEDRLEAERAMKKINGLPYDHLILGCMWSL Mnele -------------------------------------------------------------------------VGDAVFLTL--ATKKDEK-KEEKMAK-LKASGQGMVVCRICK-GPHWTKQCPYKDTL-----AYVPPSIRQR------------DENPTIRVSNLAEETSEKDLQ-DLFKPFGPVSRIYLAKDKNTGKGFAYITYNRRESAETALQTLHRYRYGHLILQVEWAK Monbr W-SEDVQDNTKRVTEYHRDEEG-QLVKKTTTYRVESRTTKASKAVIARR-KWTKFGAA-K-GAAPGPEAVTTSVGEEVYL---------LK-THEPQDAEEKPTGITSVSCRKCG-GSHFTHSCP----------AYVAPNKR-------------QEQENSVRITNLPPETQHEDLK-DLIREMAGMQRMYLAQDAVTGKGFAFVTFHTRSDAEKAIKHLDGHRYGHAIIHAELSK Morel2 W-ADEVDNGITTTIEYRTNEDG-KKVKVTRRTQKKLIHDVVNKAVAARK-KWPKFGKE-K-GNRPGPDPATTNVGDNIKLKL-SSTGDVDV---EAMKAQLQN---KKILCRICK-GDHFTTKCPYKDSL-----KYIAPHMRDSM-R-----E-KRDEQPTLRVTNLSEDVTEADVS-ELFKRFGHISRVFLARDRETNKGFAFVSFTMREDAQRALEAIDGRGYDNLILRVEWAR Mucci2 W-ADEYEDGNKVIIEFRENEDG-KKVKVTRKLRAKLVTEHVNKAVAQRK-KWAKFGEE-K-GKKAGPDLSTTTIGENIPLKLGSNTGKNAV-AEDKIQSQLKT---KNIACRICK-GEHFTSKCPYKDTM-----KYTPPHLRESM-RG---DQ-KRDDSATLRVTNLSEDVTDNDIY-DLFNRFGSIARVYLARDRDTNKGFAFVSFNDREHAERAQQAINGYGYDNLILRVEFAR Mydma W-GDMME-NIKKLIEYRFNEEG-KRVKVTRVYSLET--LKVSTSIAKRK-TWKKFGLAQR-DNPHGPDHSTTFVGEDVYLSF--TTNKEDE-DKKKL------KGSSLVKCRICK-GDHWTTKCPYKDSL-----KYMPPSLRETM-----NSRKQADEAATLRVTNLSEDACEADIQ-ELFRPFGSIARVYLAKDKITNKGFAFVSYIRREDAARAIKSLQGYGYDHLILNVEWAK Neucr2 W-ADDDEDGSTTIIEYRLNDNG-QKVKTTRRIRYITHREVVNPRVAERK-SWTKFGLS-V-KDGAGPAPDTTSVGENIIFKP--SFNWREA-KDQAMKDKLKD---KKVKCRICN-GEHFTARCPYKDTM-----SYVPPALRERM-GGKYG---ERDDLATLRVTNVSEMAEEQELR-DMFERFGRVTRVFLAKDRDTGKGFAFISFADRSDAVKACAKMDGFGFRHLILRVEFAK Orpsp11 ---------------------------VTRKIKKKLVKEAVLHVVAERK-KLKKFGAS-K-NDPSGPQEDTTNISEEIFLKL--SSNNK-----PKEKAT-----PSNIVCRYCK-GDHWTIKCPYKNTM-----KYVPPNLREK-----P----QYDEENTIRITNISEDTTDRDLQ-ELIRRFGPTQRIFLKRD----KGFAFVTFINREDAERALNTLNGYGYDSLILHVEWSN Pench1 W-ADDEDDGTKTVISYRYNDDN-KKVKVTRRIKTTVVREHVNPQVAERR-KWEKFGLE-K-GHAAGPSFDTTSVGENIIFRP--SVNWKNA-KEGSMKDQLKD---KKVKCRICS-GEHFTARCPFKDTM-----SYVPPHMREKM-GGRF----EKDDLATLRVTNVSELAEENELR-DLFERFGRVTRVFLARDRETQKGFAFISYADRGDAALACEKVDGFGYRHLILRVEFAK Phybl2 W-ADEVENGIKTIIEYRENEDG-KKVKVTRKIRSKLVTEHVNKAVAQRK-KWSKFGDE-E-GNKPGPDMATTTIGENIPLKLGSNTGKNAV-AADKVASQLKA---KNIMCRICK-GEHFTSKCPYKDTL-----KYTPPHLRESM-R----DA-KRDDSATLRVTNLSEDVTDNDIY-DLFNRFGNIARVYLARDRETSKGFAFVSFSDKDDAERAQQAINGYGYDNLILRVEFAR Picst3 W-ADAGDDGTKTVITYRTNQDG-KKVKITQKIKEVKVQERVHPLIAQRK-NWKKYGKE-S-KSPPGPDTSTTQLGEKVELKL--GTSWKEK-EEAENRAQLSV---QTIRCRTCG-GDHYTSKCPFKDTL-----KYVPRHLRE-----------GRDDSTTLKVSQLNSFVDEDMLRNELFARFGPLQRVTLVRNRETGRGFAYVSFITEDMAQRALDALNGKGYHSLILHLEWSK Plicr1 W-ADDVDNGIRTTVEYSVNDEG-KKVKITRRIKRVLQKSVVDHASAERK-KWAKFGQE-K-GNKPGPDRATTTVGENVQLKL--SAGNKTE-PESSVKTELARAGAGKVVCRLCK-GDHFTAKCPYKESLGGSGGKYVPPSMREAM-GR-PGGS--RDDLPTLRVTNISEDTQENDLR-DLFGPFGRVARVYVGRDRETGKGFAFVSFEEKAMAQKAMEKVHGRGYDNLILSVQWSQ Polpo W---------EKVIEIFVKNDG-EDVKIIKTFREYQVPVKRNKRVDERR-KWEKFGDC---AGTNG--MSNTSSGEEVFLTL--SRNTVEE-KK------------DVIVCRNCK-RNHFTSKCPYYEAI-----KYVLPSQR--------------IEVPSLIVSNLSENANEKDLR-ELFGRFGMVQKVNVPKQND-GRGFAYVTYADLKSTEEAIKHLDGHRYDYLVLSVSIAQ Pucgr2 W-ADELDTGIKTIVEYKWDETGEKKIKTVRKIKRTLVTTRVSPTVAARK-GWAKFGLE-K-GKKSGPDLATTTLGEAIKLKI-AVPGLI---KEQTTKATIVP-GGKRITCRLCQ-GDHFTASCPYKDTLGASQAKYVPPSQRESM-QK-S--N--RDDLPTLRVTNLSEDVQESDLW-DLFGRFGRISRIYVGKDQETGKGFAFVSFEDRMEAERAMKKINGLPYDHLILGCMWSL Punst1 W-ADDVDNGVRTTIEYTINDEG-KKVKITRKIKRVLQKAVVDHAVAERK-HWAKFGQE-K-GNKPGPDRATTTVGEDVRLKI--SAGNKSE-AENQVKQNLARAGAGKVVCRLCK-GGHFTAKCPYKDSLAPEPSRYVPPSLRERM-TG-PGSG-NRDDLPTLRVTNISEDTQENDLR-DLFGRFGRVARVFVGRDRETGKGFAFVSFEEKAVAERAMQKMNGFGYDNLILSVQWSQ Rhior3 W-ADEYEDGNKVIIEYRDNEDG-KKIKVTRKIQSKLITEHVNKAVAQRK-KWAKFGEE-K-GRKPGPDLATTTIGENIPLKLKSNTGKNAV-AESKIQSQLKT---KNIACRICK-GEHFTSKCPYKDTM-----KYTPPHLRETM-R-----E-KRDDSATLRVTNLSEDVTDSDIY-DLFNRFGNIARVYLARDRETNKGFAFVSFNSREDADRAQQAINGYGYDNLILRVEFAR Rhoto1 W-ADDVENGVTTIVEYRLNDEG-KKVKVTRKIKRTLVKTTVNHVVAERM-GWAKFGQE-K-GAAPGPSSATTTVGENVRLRI--QAGGIAE-EKEAMRKQLAN---KKVTCRYCS-GDHFTAHCPYKDTL-----KYVPPSLRETM-NGLRGGD--RDAYPTLRVTNLSEDASDADMW-ELFGRFGRINRIYVGKDQETGKGFGFVSFEDRADAEAALKKVHGLPYDHLILQVQWSV Rozal11 -------DGTFTQIEYRFDDNN-NILKVTRVIKKELHKSLASKSVKMRK-EWKKFGDS-A-NDTDGPQNGITSLADEIFLKL----------PSKSMAAIVKT-AAKRITCGNCG-GDHITVRCPLKNKI-----VYVAPSRR------------RKDDNCTLRVSNLPEETTERDVR-ELFKMAGYIARCYLPVDQN-RRGFCYLTFGSKEEAEKGIQIVNGHRYAHRVLNVEFAE Sacce1 -------DGSRSIITYKI-EDG-VKYKITQKVKEVKVLEKVHKSVAERK-NWHKYGSE-K-GSPAGPSAVTARLGEEVELRL--SRNWKEE-ERKASLTK------TGLQCRLCG-NDHMTMNCPFKTIL-----QYVPPSRRDAY-RD----SRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSK Salro -------GDTQKVIEV-VEEDG-KRFKQTTVYNVVREEVKMPSRVLARR-SWAKFGKS-A-RAPPGPEPMTTSISDEVFIEF--TAAREAE-QRQRQKAQMSVPYRLPVALRQ----------------------AYRAPRTR------------FDEEQPSLQITNLPPWTTDDDLR-DL----APVRRVFLAKDKRTGKGFAYVDFNMRQDAATALEKLDGHRYGPSVLSCEWAK Schco3 -------NGIRTVIEYTTNDEG-KR--ITRRTKRTLQKSVVDHQVAERK-KWAKFGQE-R-GNKPGPDPSTTTVAEVVSLK--------SE-PEDAAPKL----VGRKVVCRLCK-GQHFTAKCPYKDQLAGEPSVYVPPSLRESM-RG-AGG---RDDLPTLRVTNISEDTQENDLR-ELFGVFGRVARVYVGRDRETGKGFAFVSFEDRAIAQRAMEKVNGKGYDNLILSVQWSR Schpo1 W-ADDEDDGTKTMIEFRIDDNG-KKVKVTRVIRKTVITERVQHAVAERK-KWKKFGKE-A-GKNSGVDARTTSVGENVQLRL--QLGWTTK-EEAALAAAVKAKGSSVVRCRACK-GNHFTAQCPYKSII-----RYIAPHLRDSMFKR------ERDDSATLRVTNLSDDTREEELR-DLFRRFGGIQRVYLAKDKETGKGFAFVSYYDRDCAIKARDRLDGYGWNNLILRCEFSK Sorma W-ADDDEDGSTTIIEYRLNDNG-QKVKTTRRIRYITHREVVNPRVADRK-SWAKFGLS-A-KDGAGPAPDTTSVGENIIFKP--SFNWRDA-KDQAMKDKLKD---KKVKCRICN-GEHFTARCPYKDTM-----SYVPPALRERM-GGKYG---ERDDLATLRVTNVSEMAEEQELR-DMFERFGRVTRVFLAKDRDTGKGFAFISFADRSDAVKACAKMDGFGFRHLILRVEFAK Sphar W-GDLEGDGIKTVIEYRWNDDP-KKEKVTKTYRVEVQKRKLNKAEQERA-GWARFGDA-K-GAPKGPQSDTTSVSDDVYLTL--TSSSKDKPEEKKM------TSSKIVSCRICQ-GAHFSARCPYKDTI-----AYVPPSMRSRM-----GGRD--DDTTTVRVTNLSEDTRESDLQ-ELFRPFGMITRIFLAKDKITGKGFAFINYVRKDDAQNAIDKLCGYGYDHLILNVEWAR Spipu1 W-AEDVEDGTRVTIEYKLNDDG-KKVKIVRKTKMRLIRAQVNHAVAERKNKWKKFGEV-A-GLSAGPDTNSTSYGEKVFLKL--SSTIKDM-PQDSLKKALAAAAKSKISCRICK-GDHWTSKCPFKDTH-----KYVPPSLRESM-RT-----ERRDDFPTIRITNLSEDTSESDVK-DLVGKFGHTSRVFVARDRETNKGFAFVSFYHKEDAERALEKLNGFGYDNLILRVEWAR Sporo1 -------DGVTTIIEYRLNDEG-KKVKVTRKIKRTLVKTSVNHVVAERM-GWAKFGQE-K-GAAAGPHAATTTVGENVRLRI--QAGGIDE-PEESMRSQLKD---KKVQCRYCG-GDHFTARCPYKDTL-----KYVPPSMRETM-GG-RGGS--RDDYPTLRVTNLSEDARDDDLW-DLFGRFGKINRIYVGKDQETGKGFGFVSFESKADAETAMKKVHGLPYDHLILQVQWSV Stehi1 W-ADDVDNGIRTTIEYAINDEG-KKVKITKRIKRTLQKSLVEHAVAERK-TWAKFGHE-K-GNKPGPDRATTTVGENVTLKL--SAGNKSE-PESTVKQNLAKAGAGKVVCRLCK-GDHFTAKCPYKDTLGDSPAKYVPPSMRESM-GR-PGGAGNRDDLPTLRVTNISEDTQENDLR-DLFGTFGRVARVYVGRDRETGKGFAFVSFEDKSTAQKAMDKMHGRGYDSLILNVQWSQ Tapde11 W-SEETDTGIITEISYKF-EQG-KKFRTTRKLKIVKAVEKVTHAEAQRK-QWKKFGAE-K-GHGAGPQSDTTSIGENIKLNL--TQGYSKQ-AEKQMKNSLSG---ASVKCRICK-GDHYTARCPYKDSL-----KYVPVHMRETM-NGVRG---GRDEFPTLRVTNLSEDAEEDDLK-VLFGRHGKVAR-----------GFAFISFYDRREAEIAQKRMDGFGYDSLILRVEFSK Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 WAADEDADGITTIITWKLDEKG-RKVKHTRRVRRKMVTQVVSHAAAERK-KWPKFGDD-K-GRPSGPDRKTTIIGENIHLKI-------SK-AEQTAKAP----VGKAVVCRLCK-GAHFTAKCPYKDQL-----KYVPPSQRESM-YR------NRDDLPTLRVTSLSLDAEDDDLR-ALFEPFGRVARANVVRDRETRKGFGFVSFDNKANAETALNRMDGFGYDSLIISVSWSQ Trire2 W-ADDDDDGTKTIITYRYNDQG-QKVKTTRRVRYITQTETVNPRVAARK-TWPKFGLS-A-KDPPGPAPDTTSVGENIIFRP--SVSWRDA-KEQAMKDKLKD---KKVKCRICN-GEHFTARCPYKDTM-----SYVPPALRERMGGSKYG---ERDDFATLRVTNVSEMAEEQELR-DMFERFGRVTRVFLAKDRETGKGFAFISFADHSDAVTACQKMDGFGFKHLILRVEFAK Umbra1 W-ADEVENGLKVIVEYRDNDDG-KKVKVTRKIKTKLVTEYVNKAVAERK-KWAKFGEE-K-GNKPGPDLSTTTIGENIPLKLSSSYGKTAE-QQTKMRQALKS---KNIMCRICK-GEHFTSKCPYKDTL-----KYIAPHLRESP-R-----E-KRDDSATLRVTNLSEDVTENDIY-ELFRRFGQISRVYLARDRETGKGFAFVSFGMKEEAERAQQAVNGLGYDSLILRVEFAR Ustma22 W-ADEFDNGVKVVIEYRTNPDG-KKIKITRRVKRTLVKTKVNHEVAERK-TWTKFGQE-K-GKAAGPHSATTTIGENVVLKM--SAGNKAE-PEDKMRQQLAN---KRIVCRLCK-GDHFTTKCPYKDTLGMDPTKYVPPSMREKM-GG-LGGM-SRDDLPTLRVTNLSEDADDDDLR-ELFMRFGRVVRVYVGRDRETGKGYAFVSFENREDADRARQKVDGRGYDNLILSCQWSL Walse1 W-ADDVDSDVITTIEVRTLPDG-KRVQVTRKFKKVLKKSNVNQAVADRK-TWPKFGLE-K-GKPAGPDRATTTVGENVVLKL--SAGNDAV-EEQLMKERLKS---KKIVCRLCK-GDHFTTKCPYKSTL-----KYIPPSQRA----G-PGGP-SRDEYPTLRVTNVSEDTHEDDLR-ELFRRFGRVQRVFIGRDRETRKGFAFVSFELRSDAEKALEKVNGMGYDNLILSVQWSQ Zygro1 -------DGTKSVVTYKV-ENG-QTYKVTQKVREIKVTEKVHKSVADRK-HWSKYGAE-Q-DAPPGPNHSTTQLGEEVQLRL--SRNWREQ-EEKIT-SD------NVISCRLCG-NAHYTMNCPFKGIL-----RYIPPSRRDAY-RD----ARERDDMSTLKITQLNLNADENTLREELLFPFAPIPKVVVVRNRETGRGLSFVTFASEEIAEQALHFLNGRGFMNLILHVEWSK [Cluster1523.fasta_al_trimmed; alignment length = 318] Allma1 LEDYYDRKLWHQLTVELDR-FLIGLYENFVRDFETKLNKLTLVAGIGDAAA--KQMPDNESRITFLLSLAERVSAHLLAQTLAAGQYTTVYAHIAASEKLLDDGVDSRVSSAFYRVAADYYKKLQYAKFYKTSLLFLGCLGDVN-ELPDEAVERAHDLSLAALLSDEIYNFGELLMHQILEKLNSP-HAWLLLLAFNSGDIAAFERAPADILNQNMPFLQQKICLMALIDFVFTRT-LPFAAIAQHTRLPVH--EVEHLLMKAMA-LELIRGAIDQVDGTVTVTWVTPRVLDRTQIQGMAGMLDAWAKVQQLGAELFA Ashgo11 FEELYERKLWHQLTEKLEL-LFLRVYLNFVSKFQDKINQLKVV-HFLLLSI--KNSSNYEENLNYLNSLQDAFEGILYIDIEKAGDLVAARDLLNDISETLEDSIPLIVTGAFYSANAEYYQKHDFNSFYYTSLLYLSTLDSNV-PAQVEQQQLAYNLCIAALLGDHIYNFGELLQHPIMASIDPQ-YQWLFLHALSVGDFEHFGQLHVPILAKNESFLRQKICLITLVESVFAK--LYFDDIARATHLPKD--NVEHLVMKSIS-LGLLKGSIDQVEELVTITWVQPRIINEEQVNKMKGRLVEWEQVTKLGKGIWV Aspfu1 FEDFWERKLWHQLTNALVE-FFLPIFKTFVLSFADKINQLKFV-SLGLMAS--TECADDQERLSFLTSLADKVEAYVYALAEVAQDLDGAQKDLEVCQKVLDDSVETVVHASFYKVNADYYHKQEFAAYYKNALLYLACI-NLD-DLSSERVSRAYSLSVAALVSDTIYNFGELLLHPILDSLETP-HSWLLLFAFNRGDLTAYDVLKNKLLEQHRIFLYQKISLSALTEMVFRRP-LTFASISSETKVKPE--EIEHLVMKALS-LGLLKGAIDQVAQVAQIHWVQPKVLDMKQIEGMRNRLKDWAGVNQLGKDVWA Aurde31 LHHQYSRKLWHQLTGTLFD-IMVEIFDKFVRPIGPKLNQLRFA-ELAVKVS--QQISDPVRHVQFLADTLAQLEAHVRVLSTVAGDLEGTKTDLDVGSALLDDGVEPSVHAAFYSVASDFYKKADYGAYYKHSLLYLACI-NPETDMTDQRVSRAHDLGISALLASNIYNFGELLMHPILESLNTT-HDWLLLFVFNEGNIGKFESLKEPILQENHPFLRQKICLMALMEAVFKRA-MSFQEIAEETKLPLD--EVEHLLMKALS-LKLIRGSMDQVDQRAQITWVQPRVLSLDQIGQLAGRLSSWEKLSKVSPDLVG Batde5 FADFYDRKLWHQLTVSIEK-FALALYDNFIVDFEKKINPISLV-KFLIQVA--HQMKDPKAALSFLSAQSEKLEAYVLAVMETAGDLEGCKIAMEESEKLLDPATETVISAAFYRVSADYYNKMAYQQYYHNALLFLSSV-NID-DLSQEKQERAYNLSMSALLGESLYNFSELLMHPILDSLNTS-MEWLLLFQFNTGDMDGFEKTKLPILVNTLAFLRQKLCLMTLIEAVFKRSKMTFSEISRETRVSLE--EVEHLVMKALS-LGLIRGKIDQVDSVVIVTWVQSRVLDKSQIKTIHDRLDGWNKVLEQVQSLIV Botbo1 LQRLYDRKLWHQLTLALFK-FLVDLFNQFVKHFEDKINPLRLA-EMCVATS--KSIEEPDKLLVFLTTVLARIEANVLLLSSIAGDMDGTKVDLGVAGRLLDSDVESSVRAAYYSVAADYFKKADYVPYYKHSLLYLACV-NVETDLTEEKIARAHDLSISALLGDTLYNFGELLMHPILASLGSA-HEWILLFTFNEGNIGKFEALREPILQENYPFLRQKICLMALIEAAFKRG-MSFQTIAEETKLPHD--EVEHLVMKALS-LHLIRGTLDQVSSTAHISWVQPRVLSRQQIGELAVRLGGWEKLQKTQPELFA Botci1 FEDLWEKKLWHQLTDTLVE-FFLPIYKTFILTFADKINQLKLV-TLALSAA--SQCKDGSERLSFLEAVAKKVDAYVYATVAVAQDQDGARKDLDKSEKILDDSVETIVHAAFYRVNAEYYQKLEFASYYKNALLYLACI-DLN-DLTSERKSRAYDLSIAALVSDTIYNFGELLLHPILDTLKDD--AWLLLFAFNRGDLAAYDVLSNPLLAQHRDGLKQKIYLAALTEAVFRRP-MTFRTISEETKVRPD--EIEHLIMKALS-LGLLRGSIDQVDEIARINWVQPKVLDMGQIEGMRTRLEEWSSVNSLGQDVWA Caeel LKELWEKKLWHQLTVLTRS-LVHEFYRLFVAEWELRVNPLQLV-EICISIAQNIATKDKQKSMEFLSKIGNVIDKIAVARLHTGIDLKSIRTQIDSTQHEVDVGVT-EVHAPFYRVSSLYLRVGDFAGYYREALRYLGVE-DAN-NLTEQKQVHAVLLGFAALLGENVHNFGELLAHPILKSLGTR-ERWIVLLAFNSGDLTRFFSLGWDDLKKQKDFLTAKIRLMAVMELAVSRP-VSFKEIATKCQIPFD--EVEFLVMKALS-KDLIRGDINQVEQVVYVTWVQPRVLDNPQIMQMATRISAWNDVNSMAREILT Canalb1 LEDFYERKLWHQLTQVLDQ-IYNRLYNLFIKQFQLKLNPIKVV-DYLLESFE----NDPKETLSTLLTLKKDFEAVIYVKLQIAHQLNKAEDILIDVAPKFENNLNSKINSAYYLEKTEHAKLNNYNDYYSNGLLYLSSVTN----LTEEKNKLRYELCIAALLGDKIYNFGELILHDIFQEISSQ-YNWLLIINLNAGNVDNFNHWKAPILEQHQIFLKEKLTIMALLELVS----LSFDIISEKTNTPID--QVELIIIKTMS-LHLIEGYINQDQQYVVVSWIQPRILNLDQVKNLIQN------VEHLF----- Cangl FEHDYENKLWHQLTQNLNV-FFLRIYDTFIVKFQENINELSLV-QYLLVAL--QTISDSDEALKYLTHLKQTLNAFLFIDIEIAKELLKARDMLDVLEKTLDDNVPLLLTSSFYSANAEYYKKEDFSSFYYTSLLYLSTLEDDN-ELTEPSFELAYDLCVAALLGEKIYNFGELLQHPIMNLIRKD-YHWILLNALTVGDLEKFDKLKTLILAQNETFLRQKIRLMSLVECIFAK--LSFQDVADATQIEKD--QVEHLVIKAIS-LKLLKGSIDQVNELVTVTWVQPRIINEEQILKMKNRLVDWEQVRALGKPIWV Capow LEDYYNRKLWHQLSIKLFE-LLLDIYNNFLLDFANKLNQLTLV-DICLIIV--NRMTDAHAAVEFLRMLAEKVAAYITTTMVIAAAPATTKELLEEVGALLEDHVDLRIFSSYYRVAASYNKKGSFSEFYKDTLLFLGCT-DLA-TLPAEQQVRAFDLALAALLADDIYNFGELLVHPVLDSLSTE-HAWLLLFAFNSGNIAKFQQLKQSDLAAHEKKLTNKLALLALLELVFQRP-VSFQEIAQHTVLNVS--DVEHLLMKALA-AGLIRGSLDGVSQAVSITWVQPRVLNTAQVADMRDRLAQWRRVSEVASELIV Catan2 FDELYDRKLWHQLSVEMDK-FITNFYFQFVRDFEAKLNKLSLVAGVGQAVA--KHLPDNTSRITYLLALADRVSAHLLATTQAAGQYETVLAHISASEKRLDDGVDTRVSSAFYRVAADYYKKSAFAKFYKTSLLFLACVGDIE-EIPDEAAERAYELGLAALLSDEIYNFGELLMHPILDKLGTP-NEWLLLFTFNKGDIVAFEKGREPLLQQNLAMLQMKICLMALIDFVFTRT-IPFSAIAQHTRLPLG--EVEHLLMKALA-LNLIKGTMDQVDGTVTVTWVTPRVLDKSQVQGMVDMLDGWSKVNALGAELFT Cioin IEELYTKKLWHQLTESLVR-FVLDIYKHFISDFESKINPLALM-EMLCPFNLFYVFTDSAEALAFLEKIKEKSEAKLLCLTAIGNNFEATKKVMEECEAILGTGIS-SVHGRYYELCSNYHQLSHHNEYYKDALRYLGCT-DLD-TISPEQQERAFNLGLAGILGDKVFNFGELLQHPVLDSLDTP-RQWLLLLTFNSGDIEQLNQLAQPDLIANELKLKQKIMLLCLMEMTFARP-LKFTEIATNTGIPVE--EVEILAMKAMS-LGLVQGTIDQVEEEIHMQWVQPRVLDKQQVGKMKGKLSTWNDVLSMAQEILT CocheC53 FEDFWERKLWHELTDKLIE-FFIPFFENFIKTFANKINQLKLV-TLGLNAA--SQYQDDKERLAFVNELAKSVDAYVYATVAAARDEEGAKKKLDECEQIIDDSVETVVHASFYRASAEYYKKHEFAAYYKNALLFLACV-DLN-DLERERQSRAYDLSIAALVSDSIYNFGELLLHPILDSLNTP-HAWLLLFAFNRGDLMAYDVLKVPLLKEHQTFLYQKISLSALTETVFRRP-MTFSEISQETKVQPN--EIEHLIMKALS-LGLLKGQIDQVAEIARINWVQPKVLDMKQIEGMRTRLKEWASVNQLGKDVWA Coere1 FEDLYERKIWHQLTNLVER-FIVGIYHEFVRDWQKYMNKVKLV-LFALAAA--RQLDSISEAAEFMEKIASEVEAFALASLESANDLDATRETLEKSQRMIEAQVDPVIYASFYRVCADYYKKAAFGQYYKNALLLLACI-DVQ-ELSEDRVQRAYDLAIAALLSDTIYNFGDLLSHPILEALNTE-HEWMLLLAFNAGDIGKFEALAQPLLVQQEAFLQQKIRLMALIESMFRRQ-VPFSAVSAETKLPAG--EIEHLVMKALS-LGLIRGGIDQVDQQITVQWVQPRYLGKEQIRNLVERLAQWDRVKDTTPELFA Conco1 FLNLYNQKLWHQLTISYQE-FIIGLFQNFIQTIHNKVNPIRYV-EIGLATA--QQLSSPAEAVEFMNQINEKVEAFILSCMETAQETDSVKEAIDTCRTYLDPNAEPTIYSSFYRITADYHKRAEFTKYYQNCFLYLSCI-NVE-LLTTEATSRAHDLAISALLGEELYNFGELLMHPILQYLDGE-LDWLLIFTFNAGDISKFEASSQPLLQSHASFLRQKICLMALVEHIFQRR-VPFADIAAETRIPGA--EVEHLVMKALS-LGLIRGNIDEVDQVVKVEWIQPRYLDMNQLIKTKGKLLHWTKVQKMTPEILN Conpu1 FRTLYNKRLWHQLTLKLFD-FIVEVFTRFVRDFESRINSLRLV-ELAAKVA--RQIDNPQSHLLLLSSLLTRIEAEAHLLTTIAGDLDGARKDMDSSWEILESGVERGVSGTFYQMAADYYKKADYAPYYKNALLYLACI-DVATDLTEERLLRAHDLGIAALLGETIYNFGELLMHPILDALNTD-YDWILLFTFNEGNIGKFEAIKEPILQDSYPFLRQKICLMALIEVVFRRG-IPFQTVAAETRLPTN--EVEHLLMKALS-LNLIKGSLDQVSGVAHITWVQPRVLSREQIGHLASRLQGWDRLASVAPEVSA Copci FRSLYSRKLWHQLTLKLFQ-FFVDVFERFVRDFETKINQLRLV-EMAVKVA--KDIDNPTTHLAFLTSLAERIQAHVLLLASIAGDLEGTKNDMDSAWKILDEGVESSVNAAYYGVAADYYKKAEYGPYYRHSLLYLACV-DPEKDLTEERLLRAHDLGISAFLAETIYNFGELLMHPILNALGTQ-HEWLLLFTFNEGNIGKFEALQEPILQENYAFLRQKICLMALIEAVFQRQ-MSFQTVATETRLPLD--EVEHLVMKALS-LKLIRGSIDQVDQKVTITWVQPRVLSREQIGGLAQRLEKWNDLNAVAPEVLT Croqu1 FLDLYQRKLWYQLTTSILE-FLISLYNGFIKDFENKINSLKLV-EIAVTVS--QRYTDPSEALDFLSALAEKLEAYVLARMSAAGQTKETEQAMNECRKIIDDLVDTSVRAGFYRVSGDYYKEAAYASYYKTSLLYLACLPNLEEDLSESRVQRAHDLGLAALLGDSIYNFGELLQHPILDSLRTP-YEWILLFAFNEGNLGVFESLQEPILQNSYPFLRQKICLMALIDAVFRRS-MPFAVIASETKLPVN--EVEHLVMKALS-LGLVKGSLDQVSSTVKITWVQPRVLTRAQIEALKVKLDEWDRVLKVGSEILV CryneH991 IKDQYERKLWHNLTVTLTQ-FVIELFEKFITAVESKINALKLV-EIARRVG--REFSEPDLTLKFLQSVHSRLSAFALSLSSIAGDLSACKSSLDECEKILSDTVEPVVNAGYYGVAGDYFKKADYAPYYKNALLYLACV-DVNAELEEDRKSRAHDLCIAALLGETIYNFGELLQHPILQTLGTE-YEWIMISAFNAGEIGKFESLNEPILEASLSFLRQKICLMALIQTVFARP-MTFQSIGEATRLPVH--EVEHLIMKALS-LRLIRGSLDQVDGTADITWVQPRVLEGKQLDTLAEQFKAWESVGKTKTQVLV Crypa2 LQDLWEQKLWHELTETLVT-IFMAIYNKFILQFADKINQLKLV-DLALKAA--TQCQDLQERLAFVELVAGK-NAYVYATVAVAGKLDDARKDLDKAEKKLDDSVETVVHATFYKVNADYYYKQDFASYYRNALLYLACI-DIK-SLDAERRKRAYDLATSALVSTSIYNFGELLLHPILDALDKK-DQWLLLFIFNAGDLTRYDMLSDPLLSQHKDKLREKIYLAALTEAVFRRP-MSFATIEQETKVKPH--EIEHLVMKALS-LGLLRGTVDQVDEVANINWVQPKVLDFKQIDSMRLRLAEWNSVNQLGQDVWA Debha1 LEDYFERKLYHQLTLTLNE-FYIKIYDLFISQFSQKLNSIQVV-DFLLASFE----DDKEECLNKLLQLKETFESIIYIDLQIANNLEKSETILEHLNPKFENEFSSKINSAFYLTKCQLYKNENYNLFYLNGLLYLSSIKNK--SLSEEQQMLCYDLCIAALLGDKIYNFGELLLHDILNCF-SQ-YDWLLIHNLNSGNLKNFNKWKSPFLKTFEVFLKQKVIIMSLLELISMKS-LNFKEISEFTGTPVN--DVEHLIIKCFS-LNLIKGYINQIDEVLVVTWLQPRILNLDQVNVLYNHLCKWGQVEGLGGSIWA Dekbr2 LEDLYERKLWFQLSELLENDVYLRLFENFIMSFGDKLNQLKLV-QFLLLSI--EQCTP-EDSLEHLKMLRQKVQALIFVEVETAGNIDEATAMMDECQKKIDSSVDNRVNASYYGTNAKVMQNGDYSSYYYSSLLFLACIENID-ELG-DKEDIVRKICISGLLGDRIYNFGEIITHEIFKYL-----EWLSVIALNSGDLEVFEQIKIPELSSHIEFLKQKVCIMALIEIVFNKP-VRYSEILKSIPALKDANDVEMMVMKCLS-LGLIKGHINEVSSEVEINWIQPHTMTMEQIGHMQNKMTFWDRVKELGKGLWV Dicdi IKDTYENKLWHQLTKQIEM-IIFNFYTNFIRDFENKLRPLSLV-EICIAVA--RQF-DTDESRKFIETISQKVSAYILTLSYIAEQLQDCKKTLELAKEELQTGLDTIVYSSFYRVSTDYHMKSQASEFYKNALMYLSYC-KLE-TISEEQASLAYNLCIAALVGENVYGFGDLIANPILKALGSQ-HNWLFLKAFNIGDIQQFEGLTQTAITNNMQKLRQKISILSLLELAFRTP-ISFSKIAQATKLPLG--EIEHLLMKSLS-LNLIKGSIDQTVEIIHITWVTPRILDLNQINSMNNRIAEWEKAKTSTVDLVA Dmel IEELYNEKLWNELTIKLVT-FVLQLYQNFLSTFETKINPYGLI-QILEVVV--DNIGDKKEAIEFLEKMKDKVEAVWYLQVMQGNDLNATKKIIEELRDVLEGNVT-PVHGKYYMLASQYYRVGKHSDYYRCGLQFLGC--SMD-EYPDQWAQQAFFLGLAALLGDGVYNIGELLAHPILESLGTE-NEWLLLKAFNTGDINKFNDMKIPDLAAQEVKLRQKISLLCLMEMTFKRS-ISFTDIAQETKLPAK--EVELLIMKALA-LDLVRGEIDQVAGVVNMSWVQPRVLNRSQIVGMASTLDTWGAITNMAAEILT Enthi LQEEKEKKLYFQLTEESEK-FVSDFYELFIRDIQKKINPIKLT-QIVISVC--KGFKDYSKAIELVNSIMGDVGARCLCYSIIGKDNNGARDEIDKLTTLLEEGLEAIVYSQYHYLCTCYYEKNDANEY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 LQTLYHRKLWHQLSLKLFE-VFVDLFENFVRDFEERLNQLRLV-ELGVIVS--REIDNPARNLSFLTSLLSRIEAHVLLLSSLAGDLDGTQTDMDSAWKILDDGVDPVVNAAYYSVAADYYKKADYAPYYKNSLLYLACI-DPAKDLSEERMLRAHNLSIAALLADTIYNFGELLMHPILSSLSTP-HEWILLFTFNAGDIGKFEALQEPILQQNYPFLRQKICLMALIESVFRRN-ISFQTIAEETRLDVG--DVEHLVMKALS-LKLLRGSLDEISQTAHITWVQPRVLDREQISALADRLKAWDKLKTVAPEVLV Fusgr1 FENFWERKLWHQLTDALID-FFLQFYRVFILKFADKINQLKLV-DLALKAA--TECDEEEERLSFLQSVAKKVDAYVFALVAVAEELDGARKDLDTAERILDDSVENVVHAAFYDANAIYYQKMDFSNYYRTALLYLACI-DIN-ELSDERHKRAYHLSIAALVSTSIYNFGELLLHPILDVLKSE-HSWMLLFAFNRGDLAAYDQLSHKLLKSNSTHLRQKIYLSALTEAVFRRA-LTFATIAQETKVRPE--EIEHLIMKALS-LGLLRGTIDQVDGVAQITWVQPKVLDMKQIAAMRQRLLDWSSVNQLGKDVWA Galma1 FKKLYTRKLWHQLTQKLFQ-FFVDVFERFVRDFEGKLNQLRLA-EMGVKVA--RDIDNPQVHLTFLTALLSRIEAHVLLLASIAGDLEGTKADMDAAWKILDESVENGVNAAYYGVGADYYKKAEYAPYYRNSLLYLACV-DVERDMVEERVLRAHDLSISAFLGDTIYNFGELLMHPILDSLGTQ-HEWILLFTFNEGNIGKFEALKEPILQENYAFLRQKICLMALIESVFRRQ-MSFQTIAEETRLPVN--EVEHLVMKALS-LKLIKGSLDQVDQKALITWVQPRVLPREQIGGLAKRLEEWDKLGQVAPEVLA Ganpr1 FGDLYDRKLWHQLTVQLQT-FAVTVYNNFVKDWAKRMNQLKLV-QFAVLAA--STFADPSESAEFLHPLLASTDAHVVATMEWAGDLESTRKAMEECEKEVDEGMDAAINSSFFRVSADYYKKASYHQFYHSALLYLSSVPSVD-DIPAERQQRAADLTLAALLADDLYNFGELLQHPVLETLGTG-QAWLLLLCFNRGDMDAFEKWENPLLAASLPFLRQKLHLTALVERTFARTRMRFSDVAKETRVKED--EVEHLVMRALS-LGLVKGSIDEVERVVQITWVQTRTLDKQQIAGMRDRLGEWTKVGDM-AELLV Gloin1 FEDLYDRKLWHQLTLKIEE-FFVPLFQHFISDWENRMNKLKLV-TLGLSVV--KQFNDNNQALSFLTSLVEKVDAYVHAVMETAGDFEGTKSAIDECEKILDDSVETVIHASFYRVCAEYFKKANFPEFYKNALLYLACI-NLD-ALTDEKTNRAYDLAISALLGETIYNFGELLMHPILDALGTP-HEWLLLFAYNVGDLAKFETLQMPLLQDSFVFLRQKICLMSLIEAVFQRS-ISFSTICSVTLLPPE--EVEYLIMKALS-LKLIRGSIDQVREVVMVTWVQPRVLDLVQIDGMRQRLQEWENVKKTTPELFV Hisca1 FEDFWERKLWHQLTNALIE-FFLAIFKNFILSFADKINQLKFV-TLGLMAS--TQCEDDRERLAFLTSLADRVDAYVYAMADVAKDFEGARKDLDASERVLDDSVETVVHAAFYKVNAEYYHKLEFASYYTNALLYLACV-DVK-DLTEDCAARAYDLSIAALVSDSIYNFGELLLHPVLDSLNTQ-HAWLLLFAFNRGDLAAYDVLKNQLLEQHKTFLYQKISLAALTETVFRRP-MTFSAISEETKVQPN--EIEHLIMKALS-LGLLKGTIDQVAQMAKISWVQPKVLDMGQIEGMRNRLREWSGVNQLGKDVWA Klula1 FEDLYERKLWHQLTEKLAI-FFLRLYTQFVSKFIDKINQLNVV-EFLLQAL--QENDDTEESLQYLKDLQKEFNGNLLLDIEIAGDLVEVRDILDAIGKTLDDSVPLRVTGAYYSCNASYYQKKDFNNFYYTSLLYLSTITSEE-QQQLEQQQLAYNLCIAALLGDNIYNFGELLQHPIISSIDKE-YEWLFLNALTEGDFQKFDQIKVPILAQHESFLRQKICLMTLVESVFAK--LSFRDIADATFLPID--SVEHLVMRSIS-LGLLKGSIDQVQQLVTITWVQPRIINQEQIKKMKDNLIKWDEVSKLGKSIWV Lacbi2 FRNLYTRKLWHQLTQKLFQ-FFVDVFERFVRDFEGKINQLKLV-EMGVKVS--KDIDNPQVHLTFLTSLLSRIEAHVLLLATIAGDVEGTKTDMDEAWKILDEGVENAVNAAYYGVAADYYKKADYAPYYKHSLLYLACV-DPEKDLSEERLGRAHDLGISAFLGDTIYNFGELLMHPILDALGTQ-HEWILLFTFNEGNIGKFEALKEPILQENYAFLQQKICLMALIESVFKRN-MSFQTIAEETRLPVD--EVEHLVMKALS-LKLIRGSLDQVDQKAQITWVQPRVLSREQIGGLAKRLEKWDKLNTVAPEVLV Lenti61 FRTLYSRKLWHQLTNKLFE-FFVDVFNKFVRDFESKLNQLRLV-EMGVKVS--KEIDNPATHLQFLKDLLERVEAHVLLLATLAGDHEGTKNDIDAAWKVLDSGVEPSVNAAYYGVAADYYKKAEYAPYYKNSLLYLACI-DPAKDLTEERVLRAHDLGIAAFLGDTIYNFGELLMHPILDALSTP-HEWILLFTFNEGNIGKFEALKEPILQENYPFLRQKICLMALIESVFKRG-MSFQTIAEETRLPLD--EVEHLVMKALS-LKLIKGSLDQVDQKAQITWVQPRVLSREQIGQLAQRLSVWSKLHKVAPEVLV Malgl1 FGELRDKRLWYQLTLQIEE-FLIDLYEHFIRSFAQHVNPLRLA-SFGVIVS--RQYEDASEAMAFLQKLAGESDAHVLLTMEAANDLNGTKSAMDRCAKLLDESVEPVVHASYYRVCGNYHKKAEYADYYRNYLLFLACI-HVDADMSGEQVQCAHDLSISALLGDTIYNFGELLLHPILTTLGSD-FAWILLYAFNAGDMGRFEALSEPILYAHVPFLRQKICLMALIESIFHRP-LSFKTIASETRIPVD--EVEHLVMKALC-LGLIRGSIDQVDQLVHITWVQPRVLDTAQTEALLRRLSDWDHVEQVSPELFV Mellp23 FLDLYQRKLWYQLTTSILE-FLISLYNGFIKDFENKINSLKLV-EIAVTVS--QQYTDPSEALEFLSSLATKLEAYVLSRMSAAGQTKETELAMNECRKILDDTVDTSVRAGFYRVSGDYYKEAAYASYYKTSLLYLACLPNVNVDLSESRIQRAHDLGLAALLGDTIYNFGELLQHPILDSLNTP-YEWILLFAFNDGHLGVFESLEEPILQNSYPFMRQKICLMALIDAVFRRN-IPFTTIASETKLPVN--EVEHLVMKALS-LGLVKGSLDQVSGTAKITWVQPRVLSRSQIEGLKVKLDEWNRVMKVGTEILV Mnele MEDYYNRKLWHQLTLALLK-YVSEVHKTFVSDFDHRISSLALS-SIGLIVA---EDIPTGERIEFLESLLKKVEAKIKIMAKIGGQVEEVQELIKTLEELVNGEVT-PVHGSFYELSAKYYKKGDYNSFYRDSLRYLGCI-DLD-DLTKQKQEHAFHIGLSALLGDKVYNFGELLAHPLLESL-IA-CPWILLLAFNRGDMNKLEQLQQPDLARNEVALKQKCALLGLMELTFNRA-IPFSEVAAAVKLPVD--EVELLVMKAIS-LNLVRGSIDECDKVVNLTWVQPRVLDLSQIKEMNKRIMEWESVEKTIPELLC Monbr VETLYTRKLWHQLTQKLLE-MVVQLYEQFISDFASKINQVSYV-HLCLVVA--TQIETPEQALEFLGNIKNQVAATVLVQAAIANHESECQAQLREAEKLLDDGVT-EMHGSYYRVAAEYHKKANFAEFYINALRFLGCT-DIN-TLPEDQVQRAFDLSLAALLGEGIYNFGELLSHDILNALDTD-KAWLLLFAFNAGDLQKFEALSSPDLAANTEVLGDKIRLLALMELVFKSP-LKFDTIAQAANVTEE--AVERLVMRAMA-LGLVRGAIDQVEGLAKLNWVQPRVLDLQQVGALADRFATWEAVNEAAPELFV Morel2 FEDLYERKLWHQLTLAVQE-FVVGLYNNFISDWEAKMSQQKLV-SLGVSAA--KQIRDHKEAREFLKTLTEKVEAYVLAKMETTGDLDTTKKDLEECGKYLEDSVDPQINASFLRVSADYYKKADYAKYYKNALLYLACV-NID-DLSAEKASRANDLALSALLGDSIYNFGELLMHPILESLGTE-REWLLLFAFNSGDIGKFEALQENILQSNITALRQKICLMSLTETVFKRS-IPFGTISSETKLPLE--EVEILVMKALS-LGLIKGSIDQVDAVVRVHWVQPRVLDRNQIKGMQERLVAWENVRKTAVDVYA Mucci2 FEDLYERKLWHQLTTKILE-FFISLFQNFVAEWEDKTNKLSLV-SIALQAA--KQFSDLNESVSFLDEIIKKVDVYVLALMESANQTDDVKKAIDESEKILDDSVDTAIYANFYRVSAEYYKKANYAQYYKSALLYLACV-DVE-ELNNDRIERAYDLSLSALLGDMIYNFGELLMHPILDSLGTE-HDWLLLFAFNAGDIGKFEALKQPLLQQNQGALRRKICLMSLIEAVFRRS-IPFSEIAAETRLSID--EVEHLVMKALS-LNLIRGSIDQVDQIVVVTWVQPRVLDRDQIEGMRRKLTEWNQVKKIGGEVFA Mydma LQQFYEKRLWHELTIELLS-FIIEIYENFLSDFEHRINHLSLV-EMIIIIS--QEVTDYDKATELFKKTQDKVEANILCLTSIGNKLEETKSVIKEAQNLLDDGIT-TVHGRFYDLSSTYSKSGQFNEYYRDALRFLGCM-DIS-TLEKDLQQRAFNLSLAALLGNEVYNFGELLAHEVLQHLKTD-FAWLVLFAFNSGDIQKFIDLKQPDLAVNENALLQKITLLSLMELTFKRK-FTFDLISQESHLPKG--EVELLVMKALS-FGLIKGFIDQVDEVVHVTWVQPRVLDTNQIRTLRDLLGNWEKVKNSAPELLV Neucr2 FETLWERKLWHQLTNLLLE-FFLQFYKVFILKFADKINQLKLV-DLALKAA--TQCRDNQERLSFLEAVVKKVDAYVFATIAVASDLDGARKDLDTAERILDDSVESVVHAAFYDTNAKYFQKSDWGSYYKNALLYLACI-DVK-SLSEEQRQRAYNLAIAALVSSSIYNFGELLLHPILDALIDDRHKWLLLFAFNRGDLAAYDLLSDPLLAQHTRQLREKIYLAALTEAVFRRP-MSFSTIANETKVHPD--EIEHLIMKALS-LDLLRGTIDQVDEVAHINWVQPKVLDMQQIKNMRQRLQEWSSVDKLGQDVWA Orpsp11 --------LWHQLTLELHK-LLIPLYNEFIVEWQDKMNQIMLV-QYLARAS--QQCKDPKESLEFLVSNTEFLDAYCLSVMEAANDIEGCKASMDECEKILDPEIEPVINASFYRVSANYYKKADYPQYYRNALLYLASI-NIE-DLSEEKVERAYELSLSALLGEGLYNFGELLMHPILESLGTP-YEWLLLYAYNSGNIDAFNSIKESLLVNNLDFLRRKLCLMSLMEHVFQRTRISFSEIASETKVAED--EVEHLIMKAFS-LGILKGKIDQVDKIVMVTWVQPRVLDLEQINSLKLKLDDWEKVNKQVNKIIV Pench1 FEDYWERKLWHQLTDSLVE-FFLALFKTFVLSFADRVNQLKFV-SLGLMAA--TECTDDQERLAFLTSLASKTDAYVYALADVAKDLDGAQTDLATCQRVLDDSVETVVHASFYKVNADYYHKQEFASFYKNALLYLACI-DLQ-ELTTERASRAYNLSVAALVSDTIYNFGELLLHPILDSLQTP-HNWLLLFAFNRGDLTAYDVLKNKLLETHRVFLYQKISLSALTEMVFHRP-LSFQAIASETKVQPD--EIEHLVMKALS-LGLLRGSIDQVAQVAQIHWVQPKVLDMKQIDGMRNRLKDWAGVNQLGKDVWA Phybl2 FEDLYERKLWHQLTLKVLE-FFIPIYQQFVSQWEKQINALSLV-SIALKAA--THFKDPNDAVEFLEILVTKVDVHVHAVMEAANQLDQVKKAIDSSEKTLEDSVDTAIYASFYRVSAAYYKKGEYAAYYKSALLYLACV-NVD-ELSEEKVERAYDLAIAALLGEMIYNFGELLMHPVLDALNTQ-NDWLLLFAFNSGDIGKFEALKLPLLQENAASLSRKICLMSLIEAVFRRA-IPFSDIAAETRLPVE--EVEHLVMKALS-LNLIRGSIDQVDQIVTVTWVQPRVLDKDQIDGMRRRLEDWNQVKKIGGEVFA Picst3 LEDYYERKLWHQLTLTLDD-FYYKIYHLFITQFASKLNPIKVV-DFLLESFD----NSPQNTLDSLLQLKQQFESVIYVNLQISDDLHNSEEILSTLNAKFDN---PKINAAYYLTQCELYRTEKYNLYYLNALLYLSSVEN---NLPEDKVKLCYELGIAALLGDKIYNFGELILHDILDVISSP-YNWLLIQNLNSGNLKEFNKWKSPFLNKFDLFLKQKIIIMSLLELISLKP-LSFQEISEFTGTPVN--DVEHLIIKCFS-LDLIKGYINQIDEVLVVTWLQPRILNLDQVQVLHNHLLSWGQLDQLGGTIWA Plicr1 FRTLHTRRLWHQLTLKLFE-FFVDVFERFVRDFESKLNQLRLV-EMGVKVS--KEIDNPQTHLTFLTALLSRIEAKVLLLASIAGDLEGTKTDMDSAWKVLDEGVDTGVNAAYYGVAADYYKKAEYAPYYRNSLLYLACV-DIEKDMSEERLGRAHDLGISAFLGDTIYNFGELLMHPILSALGTP-HDWILLFTFNEGNIGKFEALKEPILQENYAFLRQKICLMALIESVFKRN-MSFQTIAEETRLPAE--EVEHLVMKALS-LKLIRGSLDQVDEKAQITWVQPRVLSREQVGQLSQRLSAWEKLNAVAPEVLA Polpo LREYYDNKLWHQLTTQIEE-FIINLYELFIKDFETKLKPLSLV-SICIVIS--SQL-DNEGSMKFIQQISEKVSGYILSLSFIAHQITEAKQTIETAREELKTGLEPIVYATFYQVCTNYCKKKSYGEFYQNALLYLSYT-RLE-TLSSDQQTLAFELGIAAIIGENVYSFGDLIVHPILRSLNTE-AAWLLLKAFNIGDIAQYEQLKVADLNNNQQQSLQKIAILSLLDLAFRTP-LPFQTIAQTTKLPLG--DIEYLLMKALS-LNLIKGNIDQIDQNIMITWVTPRVLDLNQIATMKGKILDWSKTQMSTVDLVV Pucgr2 FSDLYQRKLWYQLTIAVQE-FLISLYNNFITDFENKINSLKLV-EIAVVIS--QRFADANDALEFLSKLADKLEAYVLARMSAAGKTKETESAMDECRAIIDDSVDTSVRAGFYRVSADYFKEAAYASYYKTSLLYLACLPNVNVDLDESRIQRAHDLGLAALLGDTIYNFGELLQHQILESLGTP-FEWILLFAFNEGNLGVFESLEEPILQNSYPFLRQKICLMALIDAVFRRS-MPFGVIASETKLPIN--EVEHLVMKALS-LGLIKGSLDQISGTASITWVQPRVLNKQQIEALKKKLDDWNRVMKVGSEILV Punst1 FRTLHQRKLWHQLTLKLFE-FFVDVFERFVRDFEQRLNQLRLV-EMGVKVS--REIDNPHAHLTFLSSLLARIQAHVLLLSMLAGDIEGTKTDMDAAWTVLDAGVENAVNASYYSVAADYYKKAEYAPYYRNSLLYLACV-DPEKDMTEQRVERAHDLGLSALLGDTIYNFGELLMHPILDDLKTP-HEWILLFAFNEGSIGKFEALKEPILAENYPFLRQKICLMALIESVFKRN-MSFQTIAEETHLPIN--EVEHLLMKALS-LKLIRGSLDQVDQKAQITWVQPRVLSREQIGALAKRLEGWDKLAGVAPQLLV Rhior3 FEDYYERKLWHQLTLQILE-FFVSVFQKFVAEWEDKINKLSLV-TIALQAA--AQFSDLNESIEFLKEIVKRVDVHVLASMEVAKQVELVKKTIDESEKTLDDSVETSIYASFYRVSAEYYKQADYAQYYKNALLYLSCI-DIS-ELTMEKIERAYDLSLSALLGEMIYNFGELLMHPILDSLGTE-HDWLLLFAFNAGDIGKFEALKQPLLEQNKAALRRKICLMSLIEAVFIRS-IPFSEIAAETRLSLD--EVEHLVMKALS-LKLIRGSIDQVDQIVVVTWVQPRVLDKDQIDGMRRKLEEWNQVKRIGGEVFA Rhoto1 FERFWSNRLWFQLTRTIES-FFIDLYESFIKDFALKLDPLKHA-SIAVAVA--RTYNDGTAAVSFLDTLLPTFEPFVLVSMERGGQPEAAKEAMDQCQKVLDDSVDLAVHASFYRVSGDYWKKAEFADYYRNSLLYLACI-DIDRDLTDERAERARDLGIAALLGESLYNFGELLLHPVLDSLGTP-NEYILLFAFNKGDIDKFQSLKEPYLLQNLNTLRQKICVLALIEAVFKRPALPFSIIAKEAQVPVD--EVEHLVMKALM-LNLIRGTLDACSSVASITWVQPRVLDKTQIGGLKDRLGDWDKVQAQAPELFA Rozal11 FITLYDKKLWHQLTVELED-FVQPIYSNFIADFEKEINQLSLV-KIAHAVS--KQLKDANQAFEFMTSVANKVEALVVARLEAAGDVEFTETVIEECNKIIDMFVEPFLQATFYRVVTDFEKKANYTGYYKNALLYLACV-DVD-KMENEKVQRAVDLGLAALLSDKIYNFGELLLHPILEALGP--NEWIALFAFNCGDLQKFEQQNHTLLNQQAGFLKQKISLMALIECAFKRQ-IPFAVISQETKIPEN--EIEFLVMKALS-LNIIKGSIDQVNQVVNINWVQPRVLNREQIGSVKNSISQWERISEITKEILV Sacce1 FEKFYEEKLWFQLSESLTK-FFLRLYDNFVSKFYDKINQLSVV-KYLLASL--KDSKDFDESLKYLDDLKAQFDGILLIDSEIANDLVKARDLLDDLEKTLDDSIPLRITNSFYSTNSQYFKKNDFNSFYYTSLLYLSTL---E-PSTAERQQLAYDLSISALLGDKIYNFGELLHHPIMETIDSN-YDWLLLNALTVGDFDKFDSLKIPILAQHESFLRQKICLMTLIETVFVK--LSFEDISKATHLPKD--NVEHLVMRAIS-LGLLKGSIDQVNELVTISWVQPRIISGDQITKMKDRLVEWDQVEKLGQSIWV Salro VQTLHNRKLWHQLSVKITE-MLVELHDSFIVHFYDRINLQTYA-KMCLTVA--TQYESPHDALAFFEQCLERVLARVCIISAMANQTDVTKAKLKEAEALLEAGVT-EMHANFYRVAAEYYKQGVYHEFYTNALRYLGCI-ELD-TLGEQQVQRAFDLALAAILGKGVYNFGELLAHPILESLSTS-KEWLLLYAFNSGDLAKFEFLSDPDLKANESVMQEKIRLLALMEMVFRAP-LAFDAIGDATKTPVD--QVEMLVMKALS-LGLVRGSLDEVDSVAVLTWVQPRVLSQQQVEAMATRFNAWATVDQTAPELYA Schco3 FQTLYNRKLWHQLTLKLFE-FFVDTFLQFVRDFESRLNQLRLV-EMAVKVS--KEIANPQTHVEFLSELLSRVEAHVLLLATIAGDLEGTRTDMDAAWAVLEEGVDNGVNAAYYGLAAEYYQKGEYAPYYKNSLLYLACV-DIDKDMSEERLQRAYHLALSAFLGDTIYNFGELLMHPILGSLGTP-HEWILLFTFNEGNIGKFEALQEPLLQANYPFLRQKICLMALIESVFKRS-MGFQTIAEETRLPIN--EVEHLVMKALS-LKLIRGSLDQVDQKAQITWVQPRVLSREQVGALAKRLEDWAKLGSVTPEVLV Schpo1 MEDLYERKLWKQLTDALIV-FFLPLYTNFVNSFRPNINQLKAV-YMGLKAF--ESCSN-DEALRNLNQIVNELDAYVYSIVAIAGKLDEARELLVKASKIIDDYVESLIHSSYYSVSADYYKKADYAQYYRHCLLYLSCI-DLD-KCSTELVERAVDLSVAAILGD-IYNFGELLLHPVFELLGTQ-HEWLLVIAMNVGDLPLFERLKMPLLQSSVALLGQKIRLMALIELVFQLP-LTFDTIARATRIPSN--EVELLIMRALS-VGLITGVIDEVTQIVTISSVQSRILNHSQIASMESRLREWQNIKNLGKGVFV Sorma FETLWERKLWHQLTNLLLE-FFLQFYKVFILKFADKINQLKLV-DLALKAA--TQCRDNQERLSFLEAVVKKVDAYVFATIAVASDLDGARKDLDTAERILDDSVESVVHAAFYDTNANYFQKSDSGSYYKNALLYLACI-DVK-SLSEEQRQRAYNLAIAALVSSSIYNFGELLLHPILDALIDDRHKWLLLFAFNRGDLAAYDLLSDPLLAQHTRQLREKIYLAALTEAVFRRP-MSFSTIANETKVHPD--EIEHLIMKALS-LDLLRGTIDQVDEVAHINWVQPKVLDMKQIENMRQRLQEWSSVDKLGQDVWA Sphar FENLYERKLWHQLTVLLLD-VTIPTYNDFINAFELDMNPLSLV-VILQRVA--AHKGSDKEAAEFLVSKKETVDASLSLSLAIGSDLTAVKAILEGARPEVEDMVPLDIRGEFYALSSGYEKRGNFTNYYRDALRQLGCVSDTAAPTTTEQQKEATDLAVAALLSDDIYNFGELLAHPILTRLGTN-DEWVLIRAFNAGDVDAYEKLTHSDLVANLITVRGKMSLTALVNLIFKRP-IAFKDIAAAAKISDN--EVELLIMAAIS-RKLIEATIDGVAETTSVFWVHPRVLDRVQIGTMATKLEQWKSVEGTADAVFR Spipu1 FEDLYDKKLWHQLTNALES-FVFALYENFIVDWEKKMNQLSLV-RFVTRAS--RELRDPKESLAFLTNQADKLDAYVLATMEAAGDLEGCKAAIDECEKILDPVTEPVINASFYRVAADYYKKMAYPQYYHNALLFLSSV-SLE-ELSLEKQERAYELAISALLGEGVYNFGELLQHQILDSLGTG-YDWLMLFCFNGGDMDAFEKIKQPLLVSSIPFLRQKLCLMTLIEAVFKRSRMTFAAISQETRVLIE--EVEHLVMKALS-LGLIKGKIDEVDQIVMVTWVQPRVLDKTQIGTIRDRLGEWDKVKERAAEVFF Sporo1 -------RLWYQLTATIES-FFIDLYESFIKEFANKLDQLKLA-GIVVTVA--RTYSEGTAAVSFLEAFVNKFEPFVLVTMERAGEADETKDAMDKCEKILDDSVDLAVHASFYRVSGDYWKKAEFADYYKNSLLYLACI-NLEKDLTEERTSRAHDLGISALLG-TIYNFGELLMHPILDSLGTQ-FEVVLLFAFNAGDIARFESLKEPFLQQHFPFLREKICLLALIEAVFKRP-LPFSVISKEAQVPID--EVEHLVMKALXKLKLIRGTLDQPSSTCTISWVQPRVLDKQQIDQLKTRLTEWDKV--------- Stehi1 FRDLHSRKLWHQLTGKLAQ-FFVDVFDRFVRDFESRLNALRFV-EMGVKVS--RDIDNPAQHIAFLTDLLSRIEAHVLLLATLAGDIEGTKTDIDAAWKILDSGVENSVNAAYYSVAADYYKKAEYAPYYRNSLLYLACV-DIQADMSEERLLRAHDLGISAFLGDTIYNFGELLMHPILDALGTP-HEWILLFTFNEGNIGKFEALKEPILQENYPFLRQKICLMALIESVFRRD-MSFQTIAEETRLPLD--EVEHLIMKALS-LKLIRGSIDQVDSKATISWVQPRVLSREQIGLLAKRLQVWEKLHGVAPELLV Tapde11 FEDMWERKLWKQLTDQLID-FYVSIYNSFISTFSKHVNQLKLV-SFGIAAA--QEYESQEDALTFMQSLAKQVDAFVFATIEAAGDVEGARESTQKAGATLDDSVDQKIHAAYYRVNADYHKKAEYTAYYRNALLYLACV-KTE-ELPAEAQERAYDLSIAALLGETIYTFGELLLHPILESLNTE-HSWLFLAALNAGDLQQFESLKQPLLEQSISFLRQKICLMALIEAIFKRP-LDFQTIASETRLPVF--EVEHLLMKALS-LTLIKGSIDQVDSKIAITWVQPRILNLQQIASMHSRLLEWQDVKKISSFIEV Thetr IASLREARLYHQLTEALET-LLVAFFDEFIAPLLKYINAKSFV-KFAVLAS--RQKETPEESMAFLLEMCESVYVHVYLLTELASSVSEAKALLEEVGEVLDVEMDPLLHGFYYHIKSEYHRMGPADVFFRYTMLYLAVT-PLD-DISDVQRVLAFDLGLSALISEKIYNFGELLQHEILSSLGTP-HAWMMLAAFNAGDIAAYETLAQPVLVVNKALLSEKLAICALVQILFETP-LSFDEIAAATRLDED--RVERVLMKALS-VGLIKGRIDGIDRTVSVSWVAPRVLDRAALGTMANSLTAWAKVDSAAGELLQ Treme1 IRSAYERKLWHNLTVALTE-FVIELFEKFIVAISSKLNELRLV-EIARRVG--REYSDPALTLQFLQSVHARLEAYALSLSSIAGDLTACKKSLDECETLLDDSVEPVVYAGYYGAAGDYYKKADYGPYYKNALLYLACV-DVERELNEERKARAHDLCIAALLGDTIYNFGELMQHPILQTLGTE-YEWILIGAFNSGAIGKFEVLREPILEASLSFLRQKICLMALIQTAFERP-MTFQSVAAATRLPVH--EVEHLIMKALS-LGLIRGTLDQVDATVDISWVQPRVLESAQLETLAQQIDAWQSVGRVKEAVLV Trire2 FEDYWERKLWHQLTDALVE-FFLAFYNVFILKFADKINKLKLV-MLALKAA--TQCKDDRERLAFLQSVIKKVDALVFASVAVAGELEDAKQDLDAAEKLLDDSVEAVVHAAFYDASASYYQKADFANYYRTALLYLACI-DLS-TLSEERLRRAYYLSVAALVSTSIYNFGELLLHPILDTLRSEDNAWLLLFAYNRGDLAAYELLSNQLLKDNSDSLRQKIYLAALTEAVFRRP-MSFATISQETKVQPQ--EIEHLVMKALS-LGLLRGSIDQVSQIAHITWVQPKVLDMKQIESMRNRLLEWSNVNQLGQDVWA Umbra1 FEDLYDRKLWHQLTQKVLE-YLISLFQKFVVDWESKINKLSLV-YIGLTTA--RKFTELQDSVNFLSEIITKVDAYVYAVMEAAGQTEETKKAIDECEKILDDSVETVIYASFYRVSAEYFKEADYAQYYKGALLYLACI-DINKQLTKEREDRAFDLAIAALLGNTIYNFGELLMHPILDSWGTE-HEWLLLFAFNAGDIGKFESLELPVLQQNLDSLSRKICLMSLIEAVFKRS-IPFSDIAAETRLPND--EVEHLVMKALS-LNLIRGSIDQVDQTVNVTWVQPRVLDRDQIDGMRKRLDIWRDVNKIGGEVFA Ustma22 LQQLHDRKLWYQLTLIIEE-FLIELYDHFVRRFSPKINQLQLA-AIGVKVA--RQYADPAEALQFLEQLATKVDAYVYALMEAAGDSDGTKAAMDKCGKILDDAVETAVHASFYRVCGDFYKKAEYASYYKNSLLYLACV-NVDVDLTEARVQRAHDLSISALLGDTIYNFGELLLHPILASLSAQ-HSWLMLFAFNAGDIGRFEALKEPILAENLPFLRQKMCLMSLIESVFKRA-IGFATIAAETKLPVD--EVEHLVMKALS-LKLIRGTLDQVEQLARITWVQPRVLDHRQIQALQMRLNNWAKVEEVTPELFI Walse1 LEINYSKRLYHQLTKTLQE-IIVDLWNNFISTFKDKLNQLRLV-EIGVRVA--QEMI-PQESLNFLESLLDTLEAYVLAKISIAGNLDKAKEAMDVCERVLDDGVEASVTGAWLRVSGDYFKKAEYAAFYRTTLLYISCA-GMD-QLDAEQIQRSHDLAIAALLGDTIYNFGELLTHPILHALGTE-LEWLIIYIFNEGDITKFEVNNEPILHDSQAFLRQKICLMALIECVFKRS-MSFSTIGAETKLPLD--EVEHLIMKALS-LKLIRGTIDQVSSSASINWVQPRVLDKNQVKSLASRLNEWSKVENVAPELFA Zygro1 FELLYQQKLWHQLTERLKV-FFLTTYLKFVTTFYDRINQLNVV-EFLLQSL--RNYHDHDQSLKYLTELEQSFDGNLLIEIETAGNLVKSRDLLDDLGKTLDDSIPLKVTNAYYSTNAEYYRKNDFNNFYYTSLLYLSTVDHQE-FQQEENRQLANNLSIAALLGDKIYNFGELLNHPIMDTIDPQ-YKWILLNALTLGDFDKFDNLKVPILAEHESFLRQKICLMTLVESVFAK--LSFDDISQASHLPKD--NVEHLVMRAIS-LGLLKGSIDQVNELVNITWVQPRIINSAQISRMRDIIVDWSEVTKLGRSIWV [Cluster1545.fasta_al_trimmed; alignment length = 127] Allma1 DPCPWNVLNDAGGAFAMGAIGGGMWHFVKGARNAPRG--ERFPGAISAMKARAPVLGGNFAVWGTLFSTFDCAFRQ-KEDAWNSIMSGTLTGGVLALRSGWKAALISATVGGVLLGMIEGAGVVMNR Ashgo11 DPCPLVVLSDFGGAFAMGVIGGCVWHGIKGFRNSPLG--ERGSGAMSALKARAPVVGGNFGVWGGLFSTFDCAVRK-REDPWNAIIAGFFTGGALAIRGGWKHTRNSAITCAALLGVFEGVGLMFQR Aspfu1 DPCPWVALSDFGGAFCMGAIGGAVWHGVKGFRNSPYG--ERRIGAITAIKARAPVLGGNFGVWGGLFSTFDCAIRK-KEDPYNAIIAGFFTGGALAVRGGVKAARNSAIMCAVFLAVIEGVGIGFQR Aurde31 DPCPWVILNDFGGAFSMGAVGGAIWHGIKGARNSPRG--ERLVGAMSVVKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPKSAFGSAVACGILLGVFEGIGVLLNR Batde5 DPCPYNIVSDVGIGFSMGAIGGTFWHGFKGYRNSPQG--ERWVGAISSIKARAPIAGGNFAVWSGLFNTFDCILRA-KEDGWNPIIAGAATGAVLAVRSGPRGMALSATVGAVILAVMEGANVMISK Botbo1 DPCPWVILNDFGGAFSMGAVGGGIWHGIKGARNSPRG--ERLVGAISTIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRSAFGSAVACGILLGVFEGVGVVLNR Botci1 DPCPWVALNDFGGAFCMGAIGGAVWHGVKGFRNSPYG--ERRIGALTAIKARAPVLGGNFGVWGGLFSTFDCAVRK-KEDPYNAIIAGFFTGGALAIRGGAKAARNSAIGCAVLLGVIEGVGIGFQR Caeel EPCPYRIGDDIGSAFAMGLVGGSIFQAFGGYKNAAKG--KKLVGMMREVRMRSTLTGVQFAAWGGMFSTIDCCLRK-KEDPINSIVSGGLTGALLAIRSGPKVMAGSAILGSVILAMIEGVGLVTTR Canalb1 DPCPIVILNDFGGAFAMGVIGGCVWHGIKGFRNSPYG--ERSYGALSAIKARAPVVGGNFGVWGGLFSTFDCTVRK-REDAWNAVIAGFFTGGALAIRGGWKHTRNSAITCACLLGVFEGVGMMMQR Cangl DPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLG--ERGLGAMSAVKARAPVLGGNFGVWGGLFSTFDCAVRK-REDPWNAIIAGFFTGGALAVRGGWKHTRNSAITCACLLGVIEGVGLMFQR Capow DPCPYRILDDLGGGFAMGTVGGSLFHALRGYRNSPKG--QRMSGMVSAVKMRGQAYGTGFAMWAGTFSTFDCVFRG-KEDPWNAIGAGAVTGAVLAARSGPAAMATNAVVGAIILGVMEGAALMMNK Catan2 DPCPWVVLNDAGGAFAMGGIGGSVIHFVKGARNAPRG--ERFTGALAAMKARAPVSAGGFAVWGGLFSTFDCAFRG-KKDAWNSIMSGFTTGGVLAARAGWKASLTSATVGGLLLGMIEGAVILMSR Cioin DPCPWRILDDCGGAYTLGFLGGGLVSMVGGARNAPKGISNRLLGAMANARIKTPRTAGSFGVWGLTFSLCDCSLRQ-KEDPWNSILSGAGTGFILAIRQGMAPAIGSAAIGGVLLALIEGVGIALNR CocheC53 DPCPWVILNDFGGAFAMGAVGGAVWHGVKGFRNSPYG--ERRIGAITAIKARAPVLGGNFGVWGGLFNTYDCAVRK-KEDPWNAIIAGFFTGGSLAVRGGYKSMRNGAISCAILLAVIEGVSIGFNR Coere1 DPCPWVILNDAGGAFAMGAIGGGTWHYIKGARNSPYG--ERFRGGMNAMRARGPIIGGNFAVWGGMFSTFECVLRQ-KEDPWNAIGSGAITGGMLAARGGWKAASVSAVFGGVLLALIEGVGIAMNR Conco1 HPCPWVIVSDFGSGFAIGSIGGGVWHFAKGAKNSPSG--YRFNGAISAVKSRAPVLGGNFAVWGGLFSTFDCALRG-KQDPWNSIASGFLTGGALACRAGLTNCLVSATFGGVILGLIEGVSILAGK Conpu1 DPCPWVILNDFGGAFAMGAVGGGIWHGIKGARNSPRG--ERFVGAISTIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRSAFGSAVACGILLGVFEGVGVLLGR Copci DPCPWVILNDFGGAFSMGAVGGGIWYGIKGARNSPRG--ERFVGAISQIKARAPVTGGNFGIWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLALRSGPKSALGSAIACGILLGVFEGVGVLLGR Croqu1 DPCPWVVLNDFGGAFAMGAIGGTVWHGVKGMRNSPRG--DRLAGSLAAIKARAPVVGGNFGVWGGMFSSFDCLVRQ-KEDPWNAIISGFMTGGALAARGGMRSMIGSAIGCGVLLGVFEGVGVLFQR CryneH991 DPCPYVILNDFGGAFSMGAIGGGIWHGIKGARNSPRG--ERLVGSLSAIKARAPVLGGNFGVWGGLFSTFDCAVRQ-KEDPWNAIISGFLTGGSLALRSGPKSAFGSAVGCAILLGVFEG--VVANR Crypa2 DPCPWVILNDFGGAFCMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAVKMRAPVLGGNFGVWGGLFSTFDCAVRK-KEDPYNAIIAGFFTGGSLAIRGGYKAARNGAIGCAVLLAVIEGVGIAFSK Debha1 DPCPIVILNDFGGAFSMGVIGGCVWHGIKGFRNSPYG--ERGYGSISAIKSRAPVVGGNFGVWGGLFSTFDCSVRK-REDAWNAVIAGFFTGGALAIRGGWRHTRNSAITCACLLGVFEGVGMMMQR Dekbr2 DPCPIVILNDFGGAFAMGAIGGCIWHGIKGFRNSPYG--ERYSGAINAVKARAPVVGGNFGVWGGLFSFYDCGLRK-REDAWNAILAGFLVGGSLAIRGGKRHIFNSAVTCACVLGVFEGVGMMFSR Dicdi APCPDKIWQDAGGAFAIGYVLMGVVNIGLGFKRSPPN--KRVLYTFALLRKKSPKFGGNFAIWGSLFSGFDCTLRK-TEDTVNPIAAGALTGGILAARSGWKHSVQAAAFGGIFIGIIEAFQHMMQK Dmel EPCPHRIVDDCGGAFIMGCVGGGLFQGLKGFRNAPQGLGRRVAGSVAAIKTKSPVIGGSFAAWGAVFSIVDCSLRQ-KEDPWNSIVSGAVTGGILASRNGAAAMAGSAIIGGVLLSMIEGLGIFFTR Enthi ------------------------------------------------------------------------------------------------------------------------------- Falba EPCPWRIGEDAGGAFAMGFVGSSMINSFKGFRNAPKS-ANRIAHALRTAQRVAPVTGGSFAVWGATFSTLECTFRG-KSDSYNMIAAGTLTGGILALRSGIRSAAISAVIGGSLMAVFEMISVALNR Fomme1 DPCPWVVLNDFGGAFAMGAIGGGIWHGVKGARNSPRG--ERLVGAVSVIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFLTGGCLAARSGPRSALGSAIACSILLGVFEGVGVLLNR Fusgr1 DPCPYVILNDFGGAFCMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAIKMRAPVLGGNFGVWGGLFSTFDCAVRQ-KEDPYNAIIAGFFTGGSLAIRGGYKAARNGAIGCAVLLAVIEGVGIGFSK Galma1 DPCPWVVLNDFGGAFSMGAVGGGIWYGIKGARNSPRG--ERFVGAISSIKARAPVTGGNFGVWGGMFSTFDCAIRQ-KEDPWNAILSGFMTGGCLALRSGPRSALNSAIACGILLGVFEGVGVLMSR Ganpr1 ----------------MGSVGGAIWHGFKGFRNSPRG--ERLPGMLAAVKARSPVLGGNFAVWGGLFSAFDCGMRG-VEDPWNAIASGAITGGVLAARGGWRTAASSAVVGGVLLALIEGVGIMISR Gloin1 DPCPWVILNDTGGAFAMGAIGGGIWHFVKGAKNSPKG--ERIIGAITAVKARSPVLGGNFAVWGGLFSTFDCALRQ-KEDPWNLIASGFLTGGFLAARGGIGAATRSACFGACVLAIIEGVTFATGR Hisca1 DPCPWVALSDFGGAFSMGAIGGAVWHGVKGFRNSPYG--ERRIGAITAIKARAPVVGGNFGVWGGLFSTFDCAVRK-KEDPYNAIIAGFLTGGALAIRGGMRAARNSAIMCGCFLAVIEGVGIGFQR Klula1 DPCPIVILNDFGGAFAMGVIGGCVWHGIKGFRNSPLG--ERRAGAVSAIKARAPVVGGNFGVWGGLFSTFDCGVRK-REDPWNAIIAGFFTGGALAIRGGWKHTRNSAITCACLLGVIEGVGLMFQR Lacbi2 DPCPWVILNDFGGAFSMGAVGGGIWYGIKGARNSPRG--ERFVGAISSMKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLALRSGPRSALGSAIACGILLGVFEGVGVLVSR Lenti61 ----------------MGAVGGTIWHGIKGARNSPRG--DRLVGALSVIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDMWNGIISGFLTGGCLAARSGPRGALTSAVACGILLSVFEGVGVLMSR Malgl1 DPCPWVILNDFGGAFAMGCIGGTIWHGIKGARNSPRG--ERMLSSVSAIKARAPVLGGNFGVWGGLFTTFDCSVRQ-KEDPWNAIIAGFCTGSTLALRGGPKTAFGAGVMCGILLGVFEGVGVLMQR Mellp23 DPCPWVVLNDFGGAFAMGAIGGTVWHGVKGMRNSPRG--DRLAGSLAAIKARAPVVGGNFGVWGGMFSSFDCMVRQ-KEDPWNAIISGFMTGGALAARGGVRSMIGSAIGCGVLLGVFEGVGVLFQR Mnele EPCPYRITDDCGGAFTMGCLGGAVFSAIKGFRIAPPGIKSRLLGMTTSVKVKAPVLGGNFGTWGLTFAACDCTLRN-KEDHWNSITAGAATGGILSLRSGPQAAVTSAIIGGVLLAMIEGISIGITR Monbr EPCPYRILDDCGAAFAMGAIGGTIWHGVRGYRNAPTG--LKYREMISAVKLRAPTVGGNFAIWGALFSTFDCSFRG-KEDPWNAISSGFFTSGLLSIRYGPKTAFKAALGGAFILSLIEGVAIAINR Morel2 DPCPYVIFSDLGASFAMGAIGGGVWYGIKGAKNSPRG--ERFPGALASLKARAPVLGGNFAVWGGLFSTFDCGMRQ-KEDPWNSIASGFLTSGVLAARSGPKVALTSAALGGVFLAVIEGLGIAISR Mucci2 DPCPWVILNDLGGAFVMGAVGGGIWHSVKGAKNSPKG--ERLTGAVSAMKARAPVLGGNFAVWGGLFSTFDCGLRQ-KEDPWNSILSGGLTGGVLAARGGVKAAAVSAVVGGALLALIEGVGIGISR Mydma ---PYRIVDDCGGAFAMGAIGGGLFSFVKGWRNSPVG--HRFVGSIAAVKTRAPVLGGNFAVWGGVFSTFDCSLRG-KEDPWNSIGSGALTGAVLMARAGPGAMVRSAAVGGILLALIEGVGIMITR Neucr2 DPCPWVILNDFGGAFAMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAIKMRAPALGGNFGVWGGLFSTFDCAIRNHKEDPWNSILAGFFTGGALAVRGGYKAARNGAIGCAVLLAVIEGVGIGFQK Orpsp11 ------------------------------------------------------------------------------------------------------------------------------- Pench1 DPCPWVALSDFGGAFCMGAIGGAVWHGVKGFRNSPYG--ERRIGALTAIKARAPVLGGNFGCWGGLFSIYDCSIRK-KEDPYNAIIAGFFTGGSLAIRGGYKAARNSAIMCAVFLAVIEGVGIGFQR Phybl2 DPCPWVILNDLGGAFVMGAVGGGIWHSVKGAKNSPRG--ERLVGAVTAMKARAPVLGGNFAVWGGLFSTFDCGLRQ-KEDPWNSILSGAFTGGVLAARGGAKAATVSAVVGGSLLAVIEGVGIAITR Picst3 DPCPIVILNDFGGAFAMGVIGGCVWHGIKGFRNSPYG--ERGYGAISAIKARAPVVGGNFGVWGGLFSTFDCSVRK-REDAWNAVIAGFFTGGALAIRGGWRHTRNSAITCACLLGVFEGVGMMMSR Plicr1 DPCPWVILNDFGGAFSMGAVGGGIWHGIKGARNSPRG--ERFVGAISTIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRSALGSAVACGILLGVFEGVGVLLSR Polpo QPCPERIWTDIGVAFSMGCVFSTIGNTFSGVRNAPRG--ERIVNAFTLVRKNAPRLGGNFAVWGTLFSGFDCTLRK-KEDYVNPIAAGALTGGVLAARAGWKASVVSAAFGGAFIGLFEVFQHVIEK Pucgr2 DPCPWVILNDFGGAFAMGAIGGTVWHGVKGMRNSPKG--DRLSGSLAAIKARAPVVGGNFGVWGGMFSSFDCLVRQ-KEDPWNAILSGFMTGGALAARGGVRSMVGSAIGCGVLLGVFEGVGVLFQR Punst1 DPCPWVILSDFGGAFSMGAIGGGIWYGIKGSRNSPRG--ERLTGAITSIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRSALGSAVACGILLGVFEGVGVLLNR Rhior3 DPCPWVILNDLGGAFVMGAVGGGIWHSVKGAKNSPKG--ERLVGAVSAMKARAPVLGGNFAVWGGLFSTFDCGLRQ-KEDPWNSIISGGLTGGVLAARGGVKAAAVSAAVGSALLGLIEGIGIGISR Rhoto1 DPCPWVILNDFGGAFAMGAVGGTVWHGIKGARNSPRG--DRLLGSLSAIKARAPVVGGNFGVWGGLFSSFDCAVRQ-KEDPWNAIISGFLTGGTLAVRSGPKGMLGSAIGCGILLGVFEGVGVLVGR Rozal11 APCPWRILEDFGGAFSMGVVGSGIWNFASGFMNAPKG--KRLAGSLNAMKTHAPIRGGQFAAWGGLYSAFDCTLRG-KEDPWNAIMSGALAGGVIQARKGWSAILVSAFAGGLILGVIEGVGIAINR Sacce1 DPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLG--ERGSGAMSAIKARAPVLGGNFGVWGGLFSTFDCAVRK-REDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACLLGVIEGVGLMFQR Salro EPCPWRILDDCGGAFAMGCIGGSVWHGVKGYRSAPMG--LKYRECINAIKLRAPTVGGNFGIWGAMFSSFDCSFRG-KDDPWNAIASGFVTSGVLAARFGASTALKSAVGGGVILACIEGLTVAINN Schco3 DPCPWVILNDFGGAFAMGAVGGGILYSIKGARNSPRG--ERLAGAISSMKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRGAFGSAVACGILLGVFEGFNVLLNR Schpo1 DPCPYVILNDFGAAFSMGTIGGAIWHSIKGWRNSPPG--EKRISAIAAAKTRAPVLGGNFGVWGGLFSTFDCAVRR-KEDPWNAIIAGFFTGGALAVRGGWRATRNGAIGCACILAVFEGLGIALGR Sorma DPCPWVILNDFGGAFAMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAIKMRAPALGGNFGVWGGLFSTFDCGIRNHKEDPWNSIIAGFFTGGALAIRGGYKAARNGAIGCAVLLAVIEGVGIGFQK Sphar DPCPYRIIDDFGGAFAMGAIGGALWHAGKGFKNAPPG--IRFRSSLSAIKARAPVMGGNFAAWGGMFSTFDCTLRQ-KEDPWNAIASGALTGGVLAARGGLSVASRSAFFGGVMLALIEGLSIAINH Spipu1 DPCPYSIVNDVGVGFCMGAIGGTVWHGFKGYRNSPRG--ERFAGSLASIKARAPVLGGNFAVWSGLFNAGDCMIRG-KEDAWNPIIAGAATGAILAARSGPRVMAISAVFGGAILAVMEGVSAMLNR Sporo1 DPCPWVILNDFGGAFAMGAVGGTVWHGIKGARNSPKG--DRLLGSISAIKARAPVVGGNFGVWGGLFSTFDCAVRQ-KEDPYNAIISGFLTGGTLAVRSGPKGMIAGAVSCGILLGVFEGVGV---- Stehi1 DPCPWVILNDFGGAFAMGAVGGGIWHGIKGARNSPKG--ERFIGAISTIKARAPVTGGNFGVWGGMFSTFDCAVRQ-KEDAWNAIISGFMTGGCLAARSGPRSAFGSAVACGILLGVFEGVGVLLGR Tapde11 ------------------------------------------------------------------------------------------------------------------------------- Thetr DPCPYRILDDIGSAFAMGTIGSGAFHAFKGARAAPKG--MRMAGMVAAVKNRAAVTGGAFAIWMALFSSFDCAIRG-KEDHFNPVAAGALTGALLAIRQGPRKALQHGIAGGAVLGVFEGVGMLIEK Treme1 DPCPYVILNDFGGAFSMGAIGGGIWHGIKGARNSPRG--ERLTGSLSAIKARAPVLGGNFGVWGGLFSTFDCAVRQ-KEDPWNAIISGFLTGGSLAARAGPRSALGSAVGCGVLLGVFEGVGVLMNR Trire2 DPCPYVILNDFGGAFAMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAVKMRAPVLGGNFGVWGGLFSTFDCAVRK-KEDPYNAIIAGFFTGGSLAFRGGVKAARNNAIGCAVLLAVIEGVGIAFGK Umbra1 ------------------------------------------------------------------------------------------------------------------------------- Ustma22 DPCPWVILNDFGGAFAMGAVGGTIWHGIKGARNSPRG--ERLPGSLSAIKARAPVLGGNFGVWGGMFSSFDCAVRQ-KEDPWNAIIAGFMTGGGLAIRSGPKTAIGSGIMCGILLGVFEGVGVLMQR Walse1 DPCPYVILNDFGGAFAMGALGGTVWHGIKGARNSPRG--ERLPGSLAAIKARAPVLGGNFGVWGGMFSSFDCAVRQ-KEDSWNAIISGFFTGGCLAIRGGPKAAFGGAVGCGILLGVFEGVGVLLNK Zygro1 DPCPIVILNDFGGAFAMGAIGGCVWHGIKGFRNSPMG--ERRIGAMSALKARAPVVGGNFGVWGGLFSTFDCAVRK-REDPWNAIIGGFFTGGALAIRGGWKHTRNSAITCACLLGVIEGVGLMFQR [Cluster1587.fasta_al_trimmed; alignment length = 418] Allma1 YRTVSGVNGPLVILDNVKEIVELTLPDGTKRSGQVLEVSGKKAVVQVFEGTSGVDAKVEFTGVSEDMLGRVFNGSGKPIDKGPKVFADDYLDIMGQPINPSSRVYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFGAMGVNMETARFFKQEFEESGSLFMNLGNDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLDKFEKQFIAQGYYESRTIYESLDLAWSLLRVFPKELLNRI Ashgo11 YNTVAGVNGPLVILERVKEIVNLTLPDGSIRQGQVLEVRGDRAIVQVFEGTSGIDVKVEFTGVSDDTLGRIFDGSGRPIDNGPKVFAEDYVDINGSAINPYARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLSNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSMEDRLSLEFLENFEKTFISQGAYENRTIFESLDHAWSLLRIYPKEMLNRI Aspfu1 YNTIGGINGPLVFLDNVKEIVSLTLPDGTERSGQVLEARGNRAIVQVFEGTSGIDVKVEFTGVSEDMLGRVFDGSGRAIDKGPKVLAEDYLDINGQPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVIMTDLSAYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLYNKGVSPPINVLPSLSRLMKSAIGEGRTRKDHSDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLEKFERTFISQGPYESRTIFESLDIAWNLLRIYPKELLNRI Aurde31 YRTVSAVNGPLVVLDNVKEIVQLTLPDGTKRSGQVLEVSGKKAIVQVFEGTTGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDAMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNRETAGFFTRDFEENGSLFINLASDPTIERIITPRLALTTAEYYAYQLEKHVLVIMTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLYNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLALEFLDKFEKEFVGQGPYESRTIFESLDLAWSLLRIFPKEQLNRI Batde5 YRTVSGVNGPLVILDQVKEIVELTLPDGTRRSGQVLEVQGNKAVVQVFEGTSGVDAKVEFTGVSEDMLGRVFNGSGKAIDKGPKVFAEEYLDIQGQPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFGAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVAGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQVYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLALEFLEKFEKTYIAQGTYEGRTIFESLDLAWSLLRIFPKEMLNRI Botbo1 YRTVSAINGPLVVLDNVKEIVQLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGIDVKVEFSGVSEDMLGRIFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRTYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNKQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSPEDKLALEFLDKFETQFVSQGPYESRTIFESLDLAWSLLRIFPKEQLNRI Botci1 YNTIGGINGPLVILENVKEIVNLTLPDGTQRSGQVLEARGDRAVVQVFEGTHGIDVKVEFTGVSEDMLGRIFDGSGRAIDKGPKVLAEDYLDINGSPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHCLVILTDLTAYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLYNRGIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAASMKAVVGEEALSSEDKLSLEFLEKFERTFISQSAYESRTIYESLDQAWSLLRIYPKELLNRI Caeel YQTVCGVNGPLVILNDVKEIVKITLPDGSKRSGQVLEISKNKAVVQVFEGTSGIDAKCEFTGVSEDMLGRIFNGSGKPIDKGPPVLAEDFLDINGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSASGLPHNEIAAQIVRQGGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRIALTSAEFLAYQCKKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRDGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEFLTKFEKNFITQGHYENRSVFESLDIGWQLLRIFPREMLKRI Canalb1 YNTVGGVNGPLVILDNVKEIVNLTLPDGSVRQGQVLEVRGTKAIVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRPIDKGPKIFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETSRFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEFLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSTEDKLSLEFLEKFEKNFISQGAYENRSIFESLDLAWSLLRIYPKELLNRI Cangl YNTVSGVNGPLVILERVKEIVNLTLPDGSIRQGQVLEVRGDRAIVQVFEGTSGIDVKVEFTGVSEDTLGRIFDGSGRPTDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQISVDRQLYNKGVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFISQGAYENRTVFESLDQAWSLLRIYPKEMLNRI Capow YKTVSGVNGPLVILDNVKEIVNLTLADGTQRAGQVLEVAGNRAIVQVFEGTSGIDAKCEFTGVSEDMLGRVFNGSGKAIDKGPAVLAEDYLDIQGQPINPWSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRHDHSDVSNQLYMNYAIGKDAQAMKAVVGEEALTSEDLLYLEFLEKFEKGFIAQGPYDGRTIFDSLEIGWNLLRIFPKELLKRI Catan2 YRTVSGVNGPLVILDNVKEIVELTLPDGTKRSGQVLEVAGKKAVVQVFEGTSGVDAKVEFTGVSEDMLGRVFNGSGKPIDKGPKVFADDFLDINGQPINPSSRVYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFGAMGVNMETARFFKQEFEESGSLFMNLGNDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNNEDKLSLEFLEKFEKQFIAQGYYESRSIYDSLDLAWSLLRVFPKELLNRI Cioin YQTVSGVNGPLVILDKVKEIVTLNLADGTQRSGQVLEVSGEKAIVQVFEGTSGIDAKCEFTGTSEDMLGRIFNGSGKPIDKGPSVLPEDYLDIQGQPINPESRIYPEEMIQTGISAIDVMNSIARGQKIPIFSANGLPHNEIAAQICRQGGLVNFAIVFAAMGVNMEAARFFKSDFEQHGSLFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVSGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALTQDDMLYLEFLTKFEKSFIAQGSYENRTVFDSLDIGWELLRIFPKEMLKRI CocheC53 YNTIGGVNGPLVILDNVKEIVSLTLPDGTERSGQVLEARGNRAVVQVFEGTSGIDVQVEFTGVSEDMLGRIFDGSGKPIDKGPKVLAEDYLDINGSPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSSSGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETSRFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSSYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLDNKGIYPPINVLPSLSRLMKSAIGEGRTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLEKFERSFIAQGAYESRSIHESLDLAWSLLRIYPKELLNRI Coere1 YRTVAGVNGPLVILDNVKEIVTLTLPDGTKRAGQVLEVQGKRAVVQVFEGTSGVDTKVEFTGVSEDMLGRIFDGSGKPIDNGPKVFAEDYLDINGMPINPYSRIYPEEMIQTGVSAIDTMNSIARGQKIPIFSTAGLPHNEIAAQIVRQAGLVNFAVVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVIMTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNEDITHPIPDLTGYITEGQIYVDRQLDNRQIYPPINVLPSLSRLMKSAIGEGLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSQEDKLSLEFLDKFERTFIAQGAYENRTIYDSLDLAWSLLRIFPKEMLNRI Conco1 YRTVAGVNGPLVILDNIKEIVSLTLPDGSKRSGQVLEVQGKKAIVQVFEGTPGIDAKVEFSGVSEDMVGRIFNGSGKAIDKGPKVFAEDYLDIEGAPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSANGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQEFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLYNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLDKFERTFIAQGAYENRTIFESLDLAWSLLRIFPKELLNRI Conpu1 YRTVSAINGPLVVLDNVKEIVSLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLALEFLDKFERQFVGQGPYESRTIFESLDLAWSLLRIFPKEQLNRI Copci YRTVSAINGPLVVLDNVKEIVELTLPDGTKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDVMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLYNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAASMKAVVGEEALSAEDKLALEFLDKFERQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Croqu1 YRTVSAVNGPLVVLDNVHEIVTLTLPDGTQRGGQVLEVNGKKAIVQVFEGTSGIDVRVEFSGVSEDMLGRIFNGSGLPTDNGPKVFAEDYLDINGSPINPYKRIYPEEMIQTGISTIDAMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFRQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLSHKQIYPPINVLPSLSRLMKSAVGEGLTRMDHSDVSNQLYAKYAIGKDAASMKAVVGEEALSSEEKLALEFLDKFENTFVNQGHNENRTIFDSLDLAWSLLRIFPREQLNRI CryneH991 YRTVSAVNGPLVVLDNVSEIVQLTLPDGTTRGGQVLEVSGKKAVVQVFEGTSGVDTKISFSGVSEDMLGRVFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEESGSLFVNLASDPTIERIITPRLALTTAEYFAYQLEKHVLVVMTDMSSYADALREVSAAREEVPGRRGYPGYLYTDLATLYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQIFVDRQLSNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAVGKDAASMKAVVGEEALSADDKLALEFLDRFEKEFVGQGAYEARTIFESLDIAWELLRIFPKESLNRI Crypa2 YNTVGGVNGPLVILDNVKEIVSLTLPDGSIRQGQVLEARGNRAVVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRAIDKGPKVLAEDYLDINGSPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSSYCDALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRGLYNKGISPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLSLEFLEKFERQFISQGAYESRTIYESLDLAWSLLRIYRKDMLNRI Debha1 YNTVGGVNGPLVILDNVKEIVNLTLPDGSVRSGQVLEVKGSKAIVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRPIDKGPKIFAEDYLDINGSPINPYARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETSRFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQISVDRQLDNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSTEDKLSLEFLEKFEKNFVSQGAYENRTVFESLDQAWALLRIYPKEMLNRI Dekbr2 YNTVGGVNGPLVILQNVKEIVNLTLPDGTSRQGQVLEVKGDKAVVQVFEGTSGIDVKVEFTGVSEDMLGRVFNGSGKPIDNGPRVFAEDYLDINGSPINPYARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQASLVNFSIVFAAMGVNLETSRFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTEKHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLYNKGVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEDALSTEDKLSLEFLEKFEKTFISQGAYEDRTVFESLDKAWSLLRIYPKEMLNRI Dicdi YRTVTAVNGPLVILDNIREIVTLTLGDGTQRKGQVLEIQGKRAVVQVFEGTIGIDAKCEFSGVSEDSLGRIFNGSGKPVDKGPNVLAEEYLDIQGQPINPSVRVYPQEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETASFFKRDFEESGSLFLNLADHPTIERIITPRLALTTAEYLAYQCEKHVLVLLTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRIQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQINNRQIYPPINVLPSLSRLMKSAIGDDMTRGDHSEVSNQMYANYAIGKDVQAMKAVVGEEALSSEDKLYLEFLERFESSFVGQNHYENRDIFNSLDLGWSLLRTFPSNLLKRI Dmel YKTVSGVNGPLVILDEVKEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKCEFTGVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRI Enthi YRTVTSVNGPLVILDNIKEIVNIKLGDGSIRKGQVLEVTGNKAVVQVFEGTSGIDARCEFTGVSEDMLGRVFNGSGKPVDKGPNVIAEDYLDINGQPINPANRVYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFRQDFEENGSLFLNLANHPTIERIVTPRLALTTAEYFAYTCDMHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLASIYERAGRVNGRVGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRNMHNRQIYPPINVLPSLSRLMKSAIGEGMTREDHSEVSNQLYANYAIGKDAQSIKAVVGEEALSMEDKLALEFLDKFEQKFISQDYYESRDIFQSLDLAWSLLRTFPRDMLKRI Falba YQTVVGVNNPLVILDNVKEIVTLTLPDGTRRSGQVLEIQGKRAIVQVFEGVTGIDAKVEFSGVSEDMLGRIFNGSGKPIDKGPRVLAEDYLDIQGQPINPSSRIYPEEMIQTGISTIDAMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVSFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEFFAYQLQKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVDGREGSITQIPILTMPNDDITHPIPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRDDHGDVSNQLYATYAQGMDVAGMKA--------AEDKLYLEFLDRYENTFVRQDSYEARSIRESLEIGWSLMRTFPQEMLKRI Fomme1 YRTVSAVNGPLVVLDNVKEIVELTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKIEFTGVAEDMLGRIFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQVYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAASMKAVVGEEALSSEDKLALEFLDKFEKQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Fusgr1 YNTVGGVNGPLVILDNVKEIVTLTLPDGTERSGQVLEARGDRAVVQVFEGTSGIDVKVKFTGVSEDMLGRIFDGSGRAIDKGPKVLAEDYLDINGSPINPYSREYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSAYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVSGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQVFIDRALDNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLSLEFLEKFERQFISQGQYESRSIYESLDLAWSLLRIYPKELLNRI Galma1 YRTVSAINGPLVVLDNVKEIVQLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLALEFLDKFEHQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Ganpr1 YRTVAGVNGPLVILDNVKEIVTLTLPDGSKRSGQVLEVSGKKAVVQVFEGTAGVDVKVEFTGVSEDMLGRIFNGSGKSIDRGPKVFAEEYLDIQGQPINPYSRVYPEEMIQTGXSXIXAMNXIARGQKIPXFSAAGLPHNEXAXXICRQAXLVNFXIVFAAMGVNMETARFFKQDFEENGSLFLNLXNDPT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 YRTVASINGPLVVLDNVKEIVNLTLPDGSRRAGQVLEVQGKRAVVQVFEGTSGVDAKVEFTGVSEDMLGRIFNGSGKAIDKGPKVFAEEFLDINGSPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIVTPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTYISQGAYESRTIYESLDHAWSILRIFPKEMLNRI Hisca1 YNTIGGINGPLVILDNVKEIVSLTLPDGSEKSGQVLEARGDRAVVQVFEGTHGIDVKVEFTGVSEDMLGRIFDGSGRAIDKGPKVFAEEYLDINGSPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQASLVNFSIVFAAMGVNMETSRFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSAYCDALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGRTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSAEDKLSLEFLDKFERTFISQSPYESRTIFESLDLAWNLLRIYPKDLLNRI Klula1 YNTVGGVNGPLVILEKVKEIVNLTLPDGSVRQGQVLEVRGDRAIVQVFEGTSGIDVKVEFTGVSEDALGRIFDGSGRPIDNGPKVFAEDYLDINGSAINPYARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQISVDRQLDNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFIAQGAYEDRTVFESLDQAWSLLRIYPKEMLNRI Lacbi2 YRTVSAINGPLVVLDNVKEIVELTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLALEFLDKFEHQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Lenti61 YRTVSAVNGPLVVLDNVKEIVQLTLPDGTKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGQPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDVMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKQDFEENGSLFFNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSPEDKLALEFLDKFEKQFVGQGAYESRSIFDSLDLAWSLLRIFPKEQLNRI Malgl1 ---------PLVILEDVKEIVSLTLPDGTRRGGQVLEVSGNKAIVQVFEGTSGIDVKIELTKVSEDMLGRVFNGSGKPVDNGPRVFAEDFLDINGSPINPYARAYPEEMIQTGISTIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFTIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVVMTDMTSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDMTHPIPDLTGYITEGQIYVDRHLHNRQVYPPINVLPSLSRLMKSAIGAKHTRVDHGDVSNQMYAAYATGRDAASMKAVVGEDALSNEDKLTLEFMERFEKEFVAQGAYETRTIFDSLDIGWSLLRIMPKEMLNRI Mellp23 YRTVSAVNGPLVVLDNVHEIVMLTLPDGTQRGGQVLEVNGKKAIVQVFEGTSGIDVKVEFSGVSEDMLGRIFNGSGQPIDKGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDAMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFRQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKQIYPPINVLPSLSRLMKSAVGEGLTRKDHSDVSNQLYAKYAIGKDAASMKAVVGEEALSSEEKLALEFLEKFESTFVNQGHNENRTIFDSLDLAWSLLRIFPREQLNRI Mnele YKTVTGVNGPLVILDNVKEIVSLTLADGSVRSGQVLEISGSKAIVQVFEGTPGIDAKCEFTGVSEDMLGRMFNGSGKPIDNGPPIMAEDLLDIMGQPINPYSREYPREMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFAIIFGAMGVNMEAARFFKQDFEESGALFLNLANDPTIERIITPRIALTTAEFLAYQCEKHVLVILTDMTSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVSGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQVYVERQLHNRQIYPPINVLPSLSRLMRSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSADDHKYLEFLYKFEKKFISQGVYENRTVFESLDIGWQLLRIFPRDMLKRI Monbr YRTVSAVTGPLVILDNVKEIVNLRLADGTVRSGQVLEVQGKRAVVQVFEGTSGIDARCEFSGVAEDMLGRIFDGSGKAIDKGPRVMADDYLDIEGQPINPYRRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTNLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQISPPINVLPSLSRLMKSAIGEGMTRRDHGDVSNQLYACYAIGKDVQAMKAVVGEEALSSEDKLYLEFLDKFEGRFINQGLYENRSVFDSLDLGWELLRTFPKEMLKRI Morel2 YRTVAGVNGPLVMLDNVKEIVELTLPDGSKRAGQVLEVQGKRAVVQVFEGTPGIDAKVEFSGVSEDMLGRVYNGSGKSIDKGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEEDGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVDGRNGSITQIPILTMPNDDITHPIPDLTGFITEGQIFIDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTYIAQGNYESRTVFESLDQAWSLLRIFPKEMLNRI Mucci2 YRTVTGVNGPLVILDNVKEIVNLTLPDGSVRAGQVLEVQGKKAVVQVFEGTSGIDAKVTFTGVSEDMLGRVFNGSGKPIDKGPKIFAEDYLDVNGSPINPFSRIYPEEMIQTGVSAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTFIAQGAYESRTIYESLDLAWSLLRIFPKELLNRI Mydma YKTVSGVNGPLVILDQVKEIVTLTLSDGSKRSGQVLEVSGSKAVVQVFEGTSGIDAKCEFTGISADMLGRVFNGSGKPIDKGPPVLAEDFLDIMGQPINPWSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFAIVFAAMGVNMETARFFKRDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRVDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSDDLLYLEFLQKFEKNFISQGSYENRTVFESLDIGWKLLRIFPKEMLKRI Neucr2 YNTVGGVNGPLVILDNVKEIVTLTLPDGTQRSGQVLEARGNRAVVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRAIDKGPKVLAEEYLDINGSPINPYAREYPQEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSSYCDALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVAGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRGLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSNEDKLSLEFLDKFERSFIAQGPYESRTIFESLDLAWSLLRIYRKDMLNRI Orpsp11 ------------------EIVTLTLPDGSKRTGKVLEIQGKKAVVQVYEGTSGIDVKVEFTGVSEDVLGRIFNGSGKSIDKGPKVFAEDFLDINGQPINPYSRIYPEEMIQTGISSIDCMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFTQEFEENGALFLNMANDPTIERIITPRIALTTAEYLAYQTEKHVLVILTDMTSYADALREISAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAASMKAVVGEDALNQEDKLALEFLEKFEKSFIAQSYSENRTIYESLDLAWSLLRIFPKEMLNRI Pench1 YNTIGGINGPLVILDNIKEIVSLTLPDGSERSGQVLEARGNRAVVQVFEGTSGIDVKVEFSGVSEDMLGRTFDGSGRAIDKGPKVLAEDYLDINGQPINPYSRVYPEEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQASLANFSIVFAAMGVNMETARFFKRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLTIMTDLSAYCDALREVSAAREEVPGRRGYPGYMYTDLSTLYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLDNRGIYPPINVLPSLSRLMKSAIGEGRTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLEKFERTFISQSPYESRTIQESLDIAWNLLRIYPKELLNRV Phybl2 YRTVTGVNGPLVILDNVKEIVNLTLPDGSVRAGQVLEVQGKKAVVQVFEGTSGIDAKVTFTGVSEDMLGRVFNGSGKPIDKGPKVFADDYLDVDGSPINPSSRIYPEEMVQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVDGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYIDRQLYNRQVYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTFISQGAYESRTIYDSLDLAWSLLRIFPKELLNRI Picst3 YNTVGGVNGPLVILDNVKEIVNLTLPDGSIRQGQVLEVRGSKAIVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRPIDKGPKIFAEDYLDINGSPINPFARIYPEEMISTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETSRFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQISIDRQLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSNEDKLSLEFLEKFEKNFISQGAYENRSIFESLDLAWSLLRIYPKELLNRI Plicr1 YRTVSAINGPLVVLDNVKEIVQLTLPDGTKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRQIYPPINVLPSLSRLMKSAIGDELTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSPEDKLALEFLDKFERQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Polpo YRTVTGVNGPLVILDNIKEIVTLTLGDGTQRKGQVLEISGKRAVVQVFEGTIGIDAKCEFSGVSEDSLGRIFNGSGKPVDKGPPVLAEDYLDIQGQPINPSVRVYPREMIQTGISAIDTMNSVARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETASFFKRDFEESGSLFLNLADHPTIERIITPRLALTTAEYLAYQCEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRINGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQINNRQIYPPINVLPSLSRLMKSAIGDDMTRNDHSEVSNQMYANYAIGKDVQAMKAVVGEEALSSEDRLYLEFLEKFESKFIGQSHYENRDIFQSLELGWNLLRTFPPTMLKRI Pucgr2 YRTVSAVNGPLVVLDNVHEIVNLTLPDGTQRGGQVLEVNGKKAIVQVFEGTSGIDVRVEFSGVSEDMLGRIFNGSGQPIDKGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDAMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFRQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRLLYNKQIYPPINVLPSLSRLMKSAVGEGLTRKDHSDVSNQLYAKYAIGKDAAAMKAVVGEEALSSEEKLALEFLDKFESTFVTQGNNENRSIFDSLDLAWSLLRIFPREQLNRI Punst1 YRTVSAINGPLVVLDNVKEIVTLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKSDFEQNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQITVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLALEFLEKFEKQFVGQGPYESRTIFESLDLAWSLLRIFPKEQLNRI Rhior3 ------------------------------------------------------------------MLGRVFNGSGKPIDKGPKIFAEDYLDIDGSPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFSIVFGAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLDNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFERTFIAQGAYESRTIYESLDLAWSLLRIFPKELLNRI Rhoto1 YRTVSAVNGPLVVLDNVKEIVAITLPDGTVRGGQVLEVTGRKAIVQVFEGTSGIDVNVEFTGVSEDMLGRIFNGSGQPIDKGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDVMNSIARGQKIPIFSASGLPHNQIAAQICRQAGLVNFSIVFAAMGVNMETARFFRQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLYNKQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYSLYAIGKDAAAMKAVVGEEALSSEEKLAIEFLGRFENEFVKQGVNENRSIFDSLDLAWSLLRLFPREQLNRI Rozal11 YRTVSGVNGPLVILDNVKEIVTLTLPDGTKRSGQVLEVTGNKAVVQVFEGTSGVDSKVEFTGVSEDMLGRVFNGSGKPIDKGPKVFAEDYLDIQGQPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRNDHGDVSNQLYAKYAIGRDAQAMKAVVGEEALNQEDKLSLEFLEKFEKTYISQGYYESRTIYESLDLAWSLLRIFPKEMLNRI Sacce1 YNTVSGVNGPLVILEKVKEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRI Salro YRTVTAVNGPLVVLDNVKEIVNLRLSDGTIRSGQVLEVSGKRAVVQVFEGTSGIDAKCEFSGVSEDMLGRVFDGSGKAIDNGPRVLAEDFLDIEGQPINPYTRLYPKEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNDIAAQICRQAGLVNFAIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQISPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLEKFERHFISQGPYENRTVFQSLEKGWELLRLFPKEMLKRI Schco3 YRTVSAINGPLVVLDNVKEIVQLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDQGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKEDFESNGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRGDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLALEFLDKFERNFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Schpo1 YNTVNSITGPLVILDNIREIVNLNLPDGSVRSGQVLEVAGHKAIVQVFEGTSGVDVRIDFTGVSEDMLGRVFNGSGLPIDKGPNLLAEDYLDINGSPINPYARIYPEEMIQTGISSIDGLNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFQRDFEENGSLFLNLANDPTIERIITPRLALSASEFLAYQTEKHVLTILTDMTSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNNAIYPPINVLPSLSRLMKSAIGEGMTRNDHGDVSNQLYAMYAIGRDAASMKSVVGEEALSQEDRLALEFLGKFEKTFISQGAYENRTIFETLDLAWSLLRIFPREMLTRI Sorma YNTVGGVNGPLVILDNVKEIVTLTLPDGTQRSGQVLEARGNRAVVQVFEGTSGIDVKVEFTGVSEDMLGRIFDGSGRAIDKGPKVLAEEYLDINGSPINPYSREYPQEMISTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSSYCDALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVAGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRGLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSNEDKLSLEFLDKFERSFIAQGPYESRTIFESLDLAWSLLRIYRKDMLNRI Sphar YRTVNAVNGPLVVLENVKEIVSLTLPNGEVRSGQVLEVQGKKAIVQVYEGTSGIDASVDFSGVSEDMLGRIFNGSGNAIDNGPKIMAEDYMDIQGQPINPYVREYPEEMIQTGISTIDVMNSIARGQKIPIFSANGLPHNDVAAQICRQAGLVNFAIVFGAMGVNIETARYFKQDFEENGSLYLNLANDPTIERIITPRIALTAAEYLAYQCEKHVLVILTDMTSYAEALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVGGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYLDRQLHNKQIYPPINVLPSLSRLMKSAIGEGMTRHDHGDVSNQLYANFAIGRDVMAMKAVVGEEALSSEDLLYLEFLEKFEQQFITQGTNDNRSVIESLELGWSLLRIFPREMLKRI Spipu1 YRTVAGVNGPLVILDNVKEIVELTLPDGSKRSGQVLEVQGKRAIVQVFEGTSGVDANVEFTGVSEDMLGRVFNGSGKGIDRGPKVFAEEYLDIQGQPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFAIVFGAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVAGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFIDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKSFIAQGYYEGRTIFESLDLAWSLLRIFPKEMLNRI Sporo1 YRTVSAVNGPLVVLDNVKEIVQLTLPDGTVRGGQVLEVSGRKAIVQVFEGTSGIDVNVEFTGVSEDMLGRIFNGSGNPIDKGPKVFAEEYLDINGSPINPYARIYPEEMIQTGISTIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFRQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQISVDRQLNNKQIYPPINVLPSLSRLMKSAIGEGLTRRDHGDVSNQMYSLYAIGKDAQAMKAVVGEEALSTEEKLALEFLDRFENEFVAQGLNENRTIFESLDLAWSLLRVFPREQLNRI Stehi1 YRTVSAINGPLVVLDNVKEIVQLTLPDGSKRGGQVLEVQGKKAIVQVFEGTSGVDVKVEFTGVAEDMLGRIFNGSGNPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQIVRQAGLVNFSVVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVQGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAASMKAVVGEEALSPEDKLALEFLDKFERQFVGQGAYESRTIFESLDLAWSLLRIFPKEQLNRI Tapde11 YNTISGVNGPLVVLDNVKEIVNLTLNDGSKRQGQILEVQGSKAVVQVFEGTSGITTDVEFTGVSEDMLGRVFNGSGAPIDNGPKVFAEDYLDINGSPINPFSRVYPEEMIQTGISSIDVNNSIARGQKIPLFSSAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQTEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRALQNKQIYPPINILPSLSRLMKSAIGEGMTRVDHGEVSAQLYAKYAVGRDAAAMKAVVGEEALSQDDKLSLEFLDKFERQFITQGAYEARTIEDSLDIAWSLLRIFPREGLNRI Thetr YRTVTEVNGPLVILDNVKEIVNVTLADGTVRRGKVLEVSGGRAVVQVFEGTTGIDARVEFTGVSRDMLGRTFNGSGKPIDGGAPILAEAFLDVEGQAVNPATRTYPEEMIETGISTIDVMNSIARGQKIPLFSAAGLPHNAIAAQVCRQADLVEFAVVFAAMGVNQEVARFFQQDFETSGALFLNLASDPTIERIVTPRLALTTAEFLAFECGMHVLVIMTDLTSYADALREVSSAREEVPGRRGYPGYMYSDLASLLERAGRVDGRPGSITQLPILTMPNDDITHPVPDLTGFITEGQVFVDRALYRRELYPPIGVLPSLSRLMKSAIGEGMTRDDHSEVSNQLYAAVAIGNDVEAMKAVVGDDALTPEDMLYLAFKDQFENKFVSQGPYESRTIEQSLDLAWSLLRQFPAKMLKRI Treme1 YRTVAAVNGPLVVLDNVSEIVQLTLPDGTIRGGQVLEVSGKKAVVQVFEGTSGVDTSIAFSGVSEDMLGRVFNGSGNPIDKGPKVWAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEESGSLFVNLASDPTIERIITPRLALTTAEYFAYQLEKHVLVVMTDMSSYADALREVSAAREEVPGRRGYPGYLYTDLSTLYERAGRVEGRNGSITQVPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAVGKDAASMKAVVGEEALSSDDKLALEFLERFEKEFVGQGAYEARTIFESLDIAWELLRIFPKESLNRI Trire2 YNTVSGVNGPLVIVENVKEIVTLTLPDGTERNGQVLEARGDRAVVQVFEGTPGIDVKVKFTGVSEDMLGRIFDGSGRAIDKGPKVLPEEYLDINGSPINPFSREYPEEMIATGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFGAMGVNLETARFFTRDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDLSAYCDALREVSAAREEVPGRRGFPGYMYTDLSTIYERAGRVTGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRPLYNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALSSEDKLSLEFLDKFERQFISQGAYESRSIYESLDLAWSLLRIYPKDLLNRI Umbra1 YNTVSGVNGPLVILDNVKEIVELTLPDGSKRAGQVLEVQGKKAVVQVFEGTSGIDAKVEFTGVSEDMLGRVFSGSGKPIDKGPKVFADDYLDVNGSPINPFSRIYPEEMIQTGISPIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLYNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALTQEDKLSLEFLEKFERTFISQGPYESRTIYESLDLAWSLLRIFPKELLNRI Ustma22 YRTVSAINGPLVVLENVKEIVSLTLPDGSRRGGQVLEVSGNKAIVQVFEGTSGIDVRIEFTGVSEDMQGRIFNGSGAPIDKGPRVFAEDYLDINGSPINPFSRVYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFGAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVVLTDMTSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVAGRNGSITQIPILTMPNEDMTHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGAKHTRADHSDVSNQMYAAYATGRDAAAMKAVVGEEALSAEDKLAIEFMENFEGKFIKQGAYENRHIFESLDIGWDLLRIFPKEQLNRI Walse1 YRTVSAINGPLVILDNVKEIVQLTLPDGSKRRGQVLEVSGKKAVVQVFEGTSGVDTRIEFTGVSEDMLGRIFNGSGQPIDNGPKVFAEDYLDINGSPINPYSRIYPEEMIQTGISTIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVNFSIVFAAMGVNMETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYFAYQCEKHVLTILTDMSSYADALREVSAAREEVPGRRGYPGFMYTDLASIYERAGRVEGRNGSITQIPILTMPNNDITHPIPDLTGYITEGQVFIDQQLNNKQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEESLSGEDKLALDFLDKFERQFVNQGPYESRTIFESLDLAWDLLRTFPKEQLNRI Zygro1 YNTVRGVNGPLVILEKVKEIVNLTLPDGSVRQGQVLEVRGDRAIVQVFEGTSGIDVKVDFTGVSEDLLGRIFDGSGRPVDNGPRVFAEDYLDINGSPINPYSRIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVNFSIVFAAMGVNLETARFFKQDFEENGSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATLYERAGRVEGRNGSITQIPILSMPNDDITHPIPDLTGYITEGQIFVDRQLNNKGIYPPINVLPSLSRLMKSAIGDGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEDALSIEDKLSLEFLEKFEKTFIAQGAYEDRTVFDSLDQAWSLLRIYPKEMLNRI [Cluster1594.fasta_al_trimmed; alignment length = 232] Allma1 NEYIEKRYGRRFNHEERMRKREARSVHKNSATAQGLKAKKRHTEKIEMKKTIKAHEEKNAKG-AVPAYLLDRSAKVLSNMIKQKRKEKAGKWNVPLPKVRGIAEDEMFKVLKTGKR-QTKQWKRMVTKVTFVGDGFTRKPPKYERFIRPMGLRFKKANVTHPELGATFTLPMIGVKKNPSSPLYTQLGVITKGTIIEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINS Ashgo11 NEYIEKKHGRRLDHEERKRKREAREAHKISEKAQGWKGKKRYAEKVAMRKKIKAHEQSKLKGEALPAYLLDREAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVVKTGKS-KTKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTSGGKVVWGKYAQITNEPDRDGCVNA Aspfu1 SSYIEKQHGKRLDHDERVRKRQARESHKQSQDAQGLRAKKRHAEKIQMRKRIKAQEEKNVKKTPLPQYLLDRSAKALSSAIKDKRAEKAAKFAVPLPKVKGISEEEMFKVVNTGKKTHKKSWKRMITKPTFVGSDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPILGVKKNPQNPLYTQLGVLTKGTIIEVNVSELGLVTTSGKVVWGKYAQITNTPENDGTVNA Aurde31 NEYIEKRHGRRLDYDERKRKREAREAHRASAHAQGHKAKRRHAEKVQLRKTLRAHDERNVKG-ARPAYLLDREAKALSTALKQKRKDKAARFAVPLPKVRGIAEDEMFKVIKTGKS-KSKAWKRMVTKATFVGEGFTRKPVKLERFIRPMALRYKKANVTHPELKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGMVTAGGKVVFGKYAQITNNPENDGCINA Batde5 NFYIEKKHGRRLDHEERKRKREAREVHKTSAKAQGFKAKKRHSEKIQMKKTIKMHEERNNKG-AVPTYLLDREAKVLSNMIKQKRKEKAGKWQVPLPKVKGMDEAEVFKVVRSGKR-KIKQWKRIVTKATFVGEGFTRKPPKYERFIRPMALRYKKAHVTHPELGATFCLPILGVKKNPSSPMYTQLGVMTKGTVIEVNVSELGLVTQTGKVVWGKYAQITNNPENDGCINA Botbo1 NEYIEKRHGRRLDYEERRRKRQAREAHKSSAVAQGLKAKKRHSQKVQLKKTLKAHDERNVKG-ALPTYLLDREAKALSSAVKEKRKERAAKYAVPLPKVRGIAEEEMFKVLRTGKS-KSKAWKRMVTKATFVGEAFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLPIIGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGLVTTGGKAVWGKYAQITNNPENDGCINS Botci1 ---MEKLHGRRLDHEERSRKKAAREGHKASDDAQGLRAKKRRHEKIQMKKQIKAHEERNVKTKPLPQYLLDRSAKALSSAIKNKRAEKAAKFSVPLPKVRGIAEEEMFKVVKTGKKTAKKSWKRMITKPTFVGPDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQNPMYTQLGVLTRGTIVEVNVSDLGLVTAGGKVVWGRWAQITNNPENDGCVNA Caeel NEHIEKRHGRRLDHEERQRKKLARAAHDRSQMAKGHKAKKRYSEKVEMRKLLKQHEEKDQKG-AVPAYLLDRQGTVLSNMIKQKRKQKAGKFNVPIPQVRAVSDAEAFKVVKTGKT-NRKGWKRMVTKVTFVGESFTRKPAKFERFIRPMGLRFKKAHVTHPELQTTFHLPIVGVKKNPSSQMYTSLGVITKGTILEVNVSELGMVTQGGKVVWGKFAQVTNNPENDGCINA Canalb1 NEYIEKKHGRRLDYEERKRKKEAREGHRVAKDAQGWRAKKRYAEKVAMKKKIKAHQESKVKGEALPTYLLDRQAKAISSSIKQKRLEKADKFQVPLPKVKGISEEEMFKVIKTGKS-KSKSWKRMITKHTFVGEGFTRRPVKMERIIRPAALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNA Cangl NDYIEKQHGRRLDYEERKRKREAREVHKVAEKAQGWKGKKRYAEKVAMRKKIKAHEQSKAKGEALPTYLLDREAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVVKTGKS-KSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTSGGKVVWGKYAQITNEPDRDGCVNA Capow NEYIEKRHGYRMDHFERLRKREAREGHNRSEYAQGLKAKKRHTEKIEMKKTIKMHQERSNKG-AVPAYLLDREAKVLSNMVKQKRKEKAGKWDVPLPKVRGIGESEVFRVVKTGKR-KIKGWKRMVTKATFVGEGFTRKPPKYERFIRPMGLRFKKAHVTHPELSATFCLPIVGVKKNPQSPLYTQLGVITKGTIIEVNVSELGLVTQNGKVVWGKYAQVTNNPENDGCINA Catan2 NEYIERRYGRRMDHDERKRKRTARLVHKNSAVAQGLKAKKRHTEKIEMKKTIKAHEEKNAKG-AVPAYLLDRSAKVLSNMIKQKRKEKAGKWNVPLPKVRGIAEDEMFKVLKTGKR-QTKQWKRMVTKVTFVGDGFTRKPPKYERFIRPMALRFKKANVTHPELAATFQLPILGVKKNPNSPLYTQLGVITKGTIVEVNVSELGLVTTSGKVVWGKYAQVTNNPENDGCINA Cioin NEHIEKRHGYRLDFHERKRKKEGRMAHDRAKKAKGLKAKQRHHEKIQMKKTLKMHDKRNTKG-AVPAYLLDREAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSEAEVFRVVTTGKR-KKKAWKRMCTKVCFVPDNFTRKPPKYERFIRPMALRFKKAHVTHPELKATFCLPVIGVKKNPSSPMYTSLGVITKGTVIEINVSELGLVTQGGKVIWGKYAQVTNNPENDGCINA CocheC53 NEYIEKQHGKRFDHDERQRKKEAREGHNASKKAQGLRAKKRRKEKIQMKQKIRAHEERNVKTEALPSYLLDRSAKALSSAIKQKRNEKAARFSVPLPKVKGISEEEMFSVVKTGKKTKKKSWKRMITKPTFVGPGFTRRPVKYERFIRPMGLRYKKANVTHPELNVTVQLPIISVKKNPQQPLYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGRYAQITNNPENDGCLNA Coere1 NEYIERRHGRRLDHAERKRKREARKVHKDAAFAQGLKAKKRHAEKIQMKKTLKMHDEKNAKG-AVPAYLLDREAKVLSNMLKQKRKEKAGKWSVPLPKVRGIAEDEMFKVVKTGKS-KSKSWKRMVTKPTFVGDGFTRKPPKYERFIRPMALRYKKANVTHPELKATFQLPIIGVKKNPQSPMYTQLGVLTKGTVIEVNVADLGLVTTGGKVLWGKYAQVTNNPENDGCINA Conco1 NEYIEKRYGRRLDHDEKKRKKEARSVHKRSQFAQGLKAKKRHAEKIQMKKAIKMHEEKSTKG-AVPAYLLDREAKVLSNMVKEKRKEKAGKWNVPLPKVRGIAEDEMFKVVKTGKK-NNKAWKRMVTKATFVGDGFTRKPPKYERFIRPMALRYKKAHVTHPELGATFHLPIIGVKKNPQSPLYTQLGVMTKGTVIEVNVSELGLVTSGGKVVWGKYAQITNNPENDGCINA Conpu1 NEYIEKRHGRRLDYYERKRKKEARAVHKASSTAQGLKAKKRHAEKVQLKKTLKAHDERNVKG-ALPTYLLDREAKALSSAIKQKRKDKAAKYAVPLPQVRGIAEDEMFKVMRTGKR-KQKSWKRMVTKATFVGEGFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTTGGKVVFGKYAQITNNPENDGCINA Copci NEYIEKRHGRRLDYFERKRKREARAVHKQSAVAQGIKAKKRHAEKVQMKKTLKAHDERNVKD-ALPTYLLDREAKALSSAIKQKRKDKAAKYSVPLPKVRGIAEDEMFKVMRTGKS-KSKSWKRMVTKATFVGEGFTRKPPKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTTGGKVVFGKYAQITNNPENDGCINA Croqu1 GEYIEKRSGKRLDHEERKRKREARSVHKQSSISQGHKAKKRYREKVEMKKLIRQHDKKDVKG-ALPTYLLDREAKALSSALKEKRKEKAGKYSVPLPKVRGIAEDEVFKVMKTGKR-KQKGWKRMVTKATFVPENFTRKPVKMERFIRPMGLRVKKANVTHPELQATFQLPIIGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGLVTTGGKVVWAKYAQVTNNPELDGCVNA CryneH991 NEYMEKRHGRRLDYEEKKRKRTAREAHKASADAQGHKAKRRHAEKVQMKKTLKAHDERNVKG-ALPAYLLDRDAKALSSAVKDRRKDRAAKYSVPLPKVRGIAEEEMFKVIKTGKS-KSKSWKRMVNKATFVGEGFTRKPVKLERFIRPMGLRMTKANVTHPELKTTFQLPILGVKKNPQSPLYTSLGVLTKGTILEVNVSELGMVTTGGKVVWSKYAQITNNPENDGCINS Crypa2 NEYMEKLHGRRLDHEERTRKRAAREGHEASEKAQGLRAKKRHKEKIQMRKQIKAHEERNVKANPVPAYLLDRNAKALSSSIKNKRSEKAARFAVPLPKVRGISEEEMFKVVSTGKKTQKKGWKRMVTKPTFVGPDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQNPLYTQLGVLSKGTVLEVNVSELGLTTTSGKVVWGRYAQVTNNPENDGCVNA Debha1 NEYIEKQHGRRLDYEERKRKKAAREGHRIAKDAQGWRGKKRYSEKVAMKKKIKTHQESKVKGEALPTYLLDRQAKAISSSIKQKRLEKADKFAVPLPRVKGISEEEMFKVIKTGKQ-KSKAWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELAVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNA Dekbr2 NDYIEKEHGRRLDFEERKRKKEARESHRIAKDAHGWRGKKRYSEKVAMKKRIKAHEESKLKGEALPTYLLDREAKAISSSIKQRRMEKADKYSVPLPRVRGISEEEAFKVVRSGKS-KRKSWKRMITKHTFVGEGFTRRPVKMERIIRPAALRQKKANVTHPELGVTVLLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGVVNA Dicdi GDHIEKRFGRRLDHYEKVRKKTARAAHKRSAIAQGLKAKKRYSEKAEMKKTIAMHQERTNKG-AVPAYLLDREAKVLSNMVKQKRKEKAGKWDVPLPKVRAISEDEMFKVVKSGKR-QKKAWKRFVTKVTFVGEGFTRKPPKYERFIRPTGLRFKKAHVTHPELKSTFYLDILSVKKNPQSPTYTQLGVITKGTILEVNVSDLGLVTQTGKVVWGKMAQVTNNPENDGCINA Dmel NEYMEKLYGRRLDYEERKRKKEARLPKDRARKARGIKAKERRNEKIQIKKKIQAHEEKKVKG-ALPHYLLDRGAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSDAEVFKVLKTGKT-KRKAWKRMVTKVTFVGENFTRKPPKFERFIRPMGLRMKKAHVTHPELKATFNLPIIGVKKNPSSPMFTSLGVITKGTVIEVNISELGLVTQTGKVVWGKYAQVTNNPENDGVINA Enthi GDYIEKRFGRRFDHFERLRKKRARDAKLKALKAKGIKAKQQRKEKAAMRKKLSVNKESKVDG-AIPSYLMDRTAKVLSNMLKQKRKEKAGKWDVPLPKVKPIAESEVFKVYKSGKR-QNKAWKRLVTKATFVGENFTRKPPKYERFIRPAAMRFTKAHVTHPELKTTFNMKILGVKKNPQSPLYTQLGIITKGSIIEVDVSELGLVTSSGKIVWGKYAQVTNNPENDGCINA Falba NDYIEKRHGQRFDHAERTRKRKAREVHKQSQFAQGLRAKKRRVEKIQMKKTIKMHEERATTG-AIPAYLMDRESKVLSNMIKQKRKEKAGKWSVPLPKVRGMSEEEVFKVVKSGKR-KSNSYKRMVTKVTFVGEGFTRKPPKFERFIRPMGLRFKKAHVTHPELRTTFNLPIIGVKKNPNSALYTQLGVITKGTIIEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Fomme1 NEYIEKRHGRRLDYYEKKRKREARAAHKSSAVAQGLKAKKRHAEKVQLKKTLKAHDERNVKG-ALPTFLLDREAKAMSSAIKQRRKEKAAKYAVPLPKVRGVAEEEVFKVMRTGKN-KSKSWKRMVTKATFVGEGFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTTGGKVVFGKYAQITNNPENDGCINA Fusgr1 NEYMEKLHGRRLDHEERVRKRTAREGHKASQDAQGLRAKRRHKEKIQMKKQIKAHEERNVKTTPMPSYLLDRTAKALSSAIKNKRAEKAAKFAVPLPKVRGISEEEMFKVVKTGKKIQKKAWKRMVTKPTFVGPDFTRRNPKHERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQNPLYTQLGVLTKGTVIEVNVSELGLVTAGGKVVWGRYAQVTNNPENEGCINS Galma1 NEYIEKRHGRRLDFYERKRKREARTAHKSSAVAQGIKAKKRHAEKIQMKKTLKAHDERNVKG-ALPTYLLDREAKALSSAIKQKRKDKAAKYAVPLPKVRGIAEDEMFKVLKTGKS-KSKAWKRMVTKATFVGEGFTRKPVKMERFIRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGLVTAGGKVVFGKYAQITNNPENDGCINA Ganpr1 NEYIEKKHGRRLDHEERKRKRTAREVHKKAAFAQGLKAKKRHAEKIQMKKTLKMHDERNTKT-ALPPYLLDRQAKVLSNAIKQKRKERAAKWDVPLPKVRAVAEEEVYKVIKTGKK-GTKQWKRLVSKHTFVPATFTRLPPKYERFIRPTALRVKRAHVTHPELKATFMLDILGVKKNPNGRDMTGLGVVTKGTVIEVNVSELGLVTQSGKVVWGKYAQVTNNPENDGVVNA Gloin1 -----------MDED---------WITKSATFAQGIRAKKRHAEKIEMKKKIKQHQEKSTKG-AIPAYLLDREAKILSNMIKQKRKEKAGKWNVPLPKVRGIAEDEMFKVVKTGKN-RTKQWKRMITKATFVGDGFTRKPPKYERFIRPMALRYKKAHVTHPELGATFCLPIIGVKKNPQSPLYTQLGVLTKGTVIEVNVSELGLVTTSGKVVWGKYAQVTNNPENDGCVNA Hisca1 NEYIEKQYGERLDHEERTRKRIAREAHKQSHDAQGLRAKKRHAEKIEMKKRIRAQEEKNVKSTPLPNYLLDRSAKSLSSAIKNKRAEKAAQFSVPLPKVKGISEEEMFKVVKTGKKTAKKSWKRMITKPTFVGADFTRRPVKYERFIRPMGLRYKKANVTHPKLGVTVQLPIISVKKNPQSPMYTQLGVLTKGTIIEVNVSELGQVTASGKVLWGKFAQITNNCENDGCVNA Klula1 NEYIEKQHGRRLDHDERKRKREAREAHKISEKAQGWKGKKRYAEKVAMKKKIRAHEQSKVKGEALPTYLLDREAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVVKTGKS-KSKAWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTSGGKVVWGKYAQITNEPDRDGCVNA Lacbi2 -MATSKRHGRRLDHFERKRKREAREAHRASAYAQGIKGKKRHAQKVQMKKTLKAHDERNVKG-ALPTFLLDREAKAMSSAIKQKRKDKAAKYAVPLPKVRGIAEDEMFKVMKTGKS-KSKAWKRMVTKATFVGEGFTRKPVKMERFIRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGMVTAGGKVVFGKYAQITNNPENDGCINA Lenti61 NEYIEKRHGRRLDYYERKRKREARAVHRASATAQGLKAKKRHAEKVQMKKTLKAHDERNVKG-ALPTYLLDREAKALSTAIKEKRKDKAAKYAVPLPKVRGIAEDEMFKVMRTGKS-KKKAWKRMVTKATFVGEGFTRKPVKMERFIRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTAGGKVVFGKYAQITNNPENDGCINA Malgl1 NDYIEKRHGRRLDHEERMRKREARSAHRAAAQARGLKAKKRRAEKVQMKKTIKQHEERDVKT-ALPAYLLDREAKALSSAVKERRKDKAARYSVPLPQVRGIAEDEAFRVVKTGKR-KQNGWKRMVTKATFVGDNFTRKPPKLERFIRPTGLRFKKAHITHPDLKATFQLPIIGVKKNPQSPMYTQLGVLTKGTIIEVNVSDLGMVTTSGKVVWGKYAQITNNPENDGCVNG Mellp23 GEYIEKRSGRRLDHEERTRKREARMVHKRSAISQGHKAKQRYREKVEMKKLIRQHDKKDVKG-ALPTYLLDREAKALSSALKEKRKEKAGKYSVPLPKVRGIAEDEVFKVMKT---------------ATFVPENFTRKPVKMERFIRPMGLRMKKANVTHPELQATFQLPVIGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGLVTTGGKVVWAKYAQVTNNPELDGCLNA Mnele NEHIEKRHGKRFDHDEKLRKKNARSSHKASMKAKGLKAKKRHAEKIQMKKAIKMHEEKQTKG-AVPAYLLDREAKVLSNMVKQKRKEKAGKWTVPIPKVKAVGEDEVFKVLATGKR-RKKTWKRMVTKVTFVGEEFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLPMIGVKKNPNSPMYTQLGVITKGTVIEVNVSELGLVTTGGKVVWGKYAQVTNHPENDGCINA Monbr NEYMEKLHGRRMDHEERLRKKEARSAHRASEQAQGLKAKKRHAEKIQMKKTIAMHEEKKSKG-AIPAYLMDREAKALSNMIKQKRKEKAGKWSVPLPKVRAMGEDEVMKVVRTGKR-QKKAWKRMITKHTFVGEGFTRKPPKYERFVRPMALRTKKAHVTHPELKATFCLPIIGVKKNPNSPMFTQLGVITKGTIIEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Morel2 NEYIEKRHGRRLDHAERKRKREAREAHKSSQFAQGLRAKKRHSEKIQMKKTIKQHEEKNAKG-AVPGYLLDREAKVLSNMIKQKRKEKAGKWNVPLPKVRGIAEDEMFKVLRSGKT-KAKSWKRMVTKATFVGDGFTRKPPKYERFIRPSALRYKKAHVTHPELKATFCLPIIGVKKNPQSPLYTQLGVLTKGTVIEVNVSELGLVTTGGKVVWGKYAQITNNPELDGCVNA Mucci2 NEHIEKRHGRRLDYEERKRKREARQAHKASQYAQGLKAKKRHAEKIQMKKTIKQHEEKNAKG-AVPTYLLDREAKILSNMVKQKRKEKAGKWSVPLPTVRGMAEDEMFKVVKTGKH-KTKQWKRLVTKATFVGEGFTRKPPKYERFVRPMGLRYKKAHVTHPELKATFCLPIIGVKKNPQSPLYTQLGVITKGTVLEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Mydma NEHIEKRHGRQLDYHEKRRKKEGREPHKLALKAKGLKAKKRHAEKVQLKKTLKMHEEKKTKG-AVPAYLLDREAKVLSNMIKQKRKEKAGKWDVPLPKVKAIGEDEVFRVVRTGKS-KRKCWKRMVTKVTYVGDEFTRKPPKFERFIRPMGLRFKKAHVTHPELKATFCLPIIGVKKNPQSPMYTSLGVITKGTVIEVNVSELGLVTQGGKVVWGKYAQVTNNPENDGCINA Neucr2 NEYIEKLHGKRLDTEERARKKAAREGHKQSENAQGLRAKERHAQKIQMRKAIKQHEERNVKSNPVPAYLLDRSAKALSSQIKSKRAEKAARFSVPIPKVKGISEEELFKVVKTGKKVHKKGWKRVVTKPTFVGPDFTRRPVKYERFIRPMGLRYKKANVTHPTLNVTVQLPILGVKKNPSNPLYTQLGVLSKGTIIEVNVSDLGMVTASGKIAWGRYAQITNNPENDGCLNA Orpsp11 NEYIEKKHGRQFNYEERMRKREAREAHKKSAFAQGFKAKKRHAEKIQMKKTLKMHDERSNKG-AVPTYLLDREAKVLSNMIKQKRKEKAGKWNVPLPKVRGISEDEMFKVIKTGKS-KSKAWKRMVTKATFVGESFTRKPPKMERFIRPMALRYKKAHVTHPELRATFYLPIIGVKKNPQSAMYTQLGVMTKGTIIEVNVSELGLVTSNGKVVWGKYAQVTNNPELDGCINA Pench1 NEYIEKQHGKRLDHEERTRKRQAREGHKASHDAQGLRAKNRHKEKIQMKKRIKAQEEKNVKKTPLPQYLLDRSAKALSSAIKNKRNEKAAKFAVPLPKVKGISEEEMFKVINTGKKTHKKAWKRMITKPTFVGNDFTRRPVKYERFIRPMGLRYKKCNVTHPELAVTVQLPILSVKKNPQNPLYTQLGVLTKGTIIEVNVSELGLVTTSGKVVWGKWAQVTNTPENDGCVNA Phybl2 NEHIEKRHGRRLDYEERKRKREARKVHKDSQYAQGLKAKKRRAEKIQMKKTIKKHEERNAKG-AVPAYLLDREAKILSNMVKQKRKEKAGKWSVPLPAVRGMAEDEMFKVVKSGKS-KTKSWKRMVTKATFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFQLPIIGVKKNPQSPLFTHLGVITKGTVLEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Picst3 NEYIEKQHGRRLDHEERKRKKEAREGHRIAKDAQGWRAKKRYSEKVAMKKKIKAHQESKVNGEALPTYLLDRQAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKS-KHKSWKRMITKHTFVGEGFTRRPVKMERIIRPAALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNA Plicr1 NEYIEKRHGRRLDYYERRRKREAREAHRSSAHAQGLKAKRRHAEKVQLKKTLKAHDERNVKG-ALPTYLLDREAKALSTAIKQKRKDKAAKYAVPLPKVRGIAEDEMFKVMKTGKS-KSKSWKRMVTKATFVGEGFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGMVTTGGKVVFGKYAQITNNPENDGCINA Polpo GDYIEKRFGRRFDHYEKLRKRTSRETHKKSALAQGIKAKKRYSEKAEMKRTIAMHQERTNKG-AVPGYLLDREAKVLSNMVKEKRKEKAGKWAVPLPKVRAISEDEMFKVVKTGKR-QKKAWKRMVTKVTFVGEGFTRKAPKYERFIRPTGLRFKKAHVTHPELKSTFYLDILGVKKNPQSPTYTQLGVITKGTIIEVNVSDLGLVTQTGKVVWGKFAQVTNNPENDGCINA Pucgr2 GEYIEKRSGKRLDHDERKRKREAREVHKRSSISQGHKAKKRYSEKVEMKKRIREHEKKDVKG-ALPTYLLDREAKALSSALKEKRKEKAGKYSVPLPKVRGIAEDEVFKVMKTGKR-KQKAWKRMVTKATFVPENFTRKPVKMERFIRPMGLRVKKANITHPELQATFQLPIIGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGLVTTGGKVVWAKYAQVTNNPELDGCVNG Punst1 NEYIEKRHGRRLDYYERKRKREARESHKASAIAQGIKAKKRHAQKVQMKKTLKAHDERNVKG-ALPAYLLDREAKALSSAIKEKRKEKAAKYAVPLPKVRGIAEDEMFKVMRTGKS-KSKSWKRMVTKATFVGEGFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTAGGKVVFGKYAQITNNPENDGCINA Rhior3 NEHIEKRHGRRLDYEERKRKKEARMAHKSSQIAQGLKAKKRHAEKIQMKKAIKQHEEKNAKG-AVPTYLLDREAKILSNMVKQKRKEKAGKWSVPLPTVRGIAEDEMFKVMKTGKN-KSKQWKRLVTKATFVGEGFTRKPPKYERFVRPMGLRYKKAHVTHPELKATFCLPIIGVKKNPQSPLYTQLGVITKGTVLEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Rhoto1 NEYIERRNGRRLDHEERKRKRAAREAHKASHVAQGHKAKRRYAEKVAMKKTIKAHEERDVKG-ALPTYLLDREAKALSSAVKQKRKEKAGKFAVPLPKVRGIAEDEMFKVIKTGKS-KRKGWKRMVTKATFVGEDFTRKPPKLERFIRPSALRMKKANVTHPELKATFQLPIIGVKKNPQSPMYTQLGVITKGTVIEVNVSELGLVTAGGKVVWGKYAQVTNNPELDGCCNA Rozal11 -----------------MKRKKARLVHERSQMAQGLKAKKRYAEKIQMKKALNQHQQKEKKG-AIPAYLLDREAKVLSNMVKQKRKEKAGKWNVPLPKVKGVGEDEVFKVLKTGKN-KTKAWKRMITKPTFVGDGFTRRPPKYERFIRPMGLRMKKAHVTHPELKATFCLPILGVKKNPNSALYTQLGVLTKGTIIEVNVSELGLVTTGGKVVWGKYAQITNNPDLDGCVNA Sacce1 NDYIEKQHGKRLDHEERKRKREARESHKISERAQGWKGKKRYAEKVSMRKKIKAHEQSKVKGDALPTYLLDREAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVIKTGKS-RSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILAVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTAGGKVVWGKYAQVTNEPDRDGCVNA Salro NEHIEKLHGRRLDHEERMRKKAAREVHRVSKQAQGIKAKKRHAEKIQMKKTLAMHEERKSKG-AIP-------------------------------------------------------------------------------------------RVSYGSLKATFKLPILGVKKNPSSPLFTQLGVITKGTILEVNVSELGLVTTGGKVVWGK---------------- Schco3 NEYIEKRHGRRLDYFEKKRKKEAREAHKFSAHAQGLKAKRRHAEKVQLKKTLKAHDERNVKG-ALPTYLLDREAKALSSAIKQKRKDKAAKYAVPLPKVRGIAEDEMFKVMRTGKS-KSKSWKRMVTKATFVGEGFTRKPVKMERFVRPMALRYKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGMVTTGGKVVFGKYAQITNNPENDGCINA Schpo1 NEYIERKHGRRFDHEERKRKKAAREAHDASLYAQGIKAKKRRKEKIQMKKTIKQHEERNATG-AVPTYLLDREAKMLSSAVKQKRKEKAAKYSVPLPQVRGVAEEEMFKVIRTGKS-KKNSWKRMITKATFVGDGFTRRPVKYERFIRPMALRQKKANVTHKELGVTMQLPIIGVKKNPQSPTYTQLGVLTKGTVIEVNVSELGLVTSGGKVVWGKYAQITNNPELDGCVNA Sorma NEYIEKLHGKRLDTEERARKKAAREGHKQSQDAQGLRAKERHAQKIQMRKQIKQHEERNVKRSRLPARPF---CEGF--EIKSKRAEKAARFSVPIPKVKGISEEELFKVVKTGKKVHKKGWKRVVTKPTFVGPDFTRRPVKYERFIRPMGLRYKKANVTHPTLNVTVQLPILGVKKNPSNPLYTQLGVLSKGTIIEVNVSDLGMVTASGKIAWGRYAQITNNPENDGCLNA Sphar NEYIEKRHGKRLDHDERKRKREARAVHDSSAKAQGLKAKKRHNEKVQMKKTLKMHDERTNKG-AVPAYLIDREAKVLSNMIKQKRKEKAGKWNVPIPKVAAVAENEVFKQISSGKR-QKKGWKRLITKATFVGEGFTRKPAKYERFIRPMAMRYTKAHVTHPELKATFHLPIIGVKKNPSSPMYTQLGVMTKGTVIEVNVSELGLVTTTGKVVWGKYAQISNNPELDGVINA Spipu1 NEYIEKKHGRRLDHEERKRKKEAREVHARAAHAKGLKAKKRHAEKVQMKKTIKMHEERNNKG-AVPTYLLDREAKVLSNMIKQKRKEKAGKWQVPLPKVKGMDEAEVFKVLKTGKR-KTKQWKRVVTKATFVGEGFTRKPPKYERFIRPMALRYKKAHVTHPELGATFCLPILGVKKNPSSPMYTQLGVITKGTVIEVNVSELGLVTQSGKVVWGKYAQVTNNPENDGCINA Sporo1 NEYIERRNGRRLDHEERTRKKTARLAHKASSEAQGHKAKRRYAEKVAMKKTIKAHEERDVKG-ALPTYLLDREAKALSSAIKQKRKEKAGKFAVPLPKVRGIAEDEMFKVLKSGKT-RRKGWKRMVTKATFVGEDFTRKPPKLERFIRPTALRYKKANVTHPELKATFQLPIIGVKKNPQSPMYTQLGVMTKGTVIEVNVSELGLVTTGGKVVWGKYAQITNNPELDGCINS Stehi1 NEYIEKRHGRRLDYYEKKRKREARAVHRQSAVAQGIKAKKRHAEKVQLKKTLKAHDERNVKG-ALPTYLLDREAKALSSAIKQKRKDKAAKFAVPLPKVRGIAEDEMFKVMRTGKS-KSKSWKRMVTKATFVGEGFTRKPVKMERFIRPMALRFKKANVTHPDLKATFQLQILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTAGGKVVFGKYAQVTNNPENDGCINA Tapde11 NEYIEKRYGKRLDHEERKRKKTAREAHAKSAHAQGIKAKKNANEKIQLKKTLRQHEERNTKG-AVPAYLLDREAKMLSNMVKQKRKEKAAKYSVPLPKVRGIAEDEMFKVVKTGKK-NQKAWKRMLTKATFVGDGFTRRPVKYERFIRPMALRQKKANVTHPELRVTMQFPILGVKKNPQSPMYTQLGVLTKGTVIEVNVSELGMVTAGGKVVWGKYAQITNNPEMDGCVNA Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ---MDRRHGRRLDYEEKKRKREAREVHKTSQDTQGHKAKKRHSEKVQMKKTLKAHDERNVKG-ALPTYLLDREAKALSSAIKDRRKDRAAKYAVPLPKVRGIAEEEMFKVIKTGKS-KQKSWKRMVNKATFVGEGFTRKPVKLERFIRPMGLRMTKANVTHPELKTTFQLPIIGVKKNPQSPLYTSLGVLTKGTIIEVNVSELGLVSTGGKVVWAKYAQITNNPENDGCINS Trire2 NEYMEKLHGRRLDHEERTRKRIAREGHKASQDAQGLRAKKRHNEKIQMKKAIKAHEERNVKSQPLPSYLLDRSAKALSSAIKNKRAEKAAKFSVPLPKVRGISEEEMFKVVKTGKKTHKKGWKRVITKPTFVGPDFTRRNPKYERFIRPMGLRYKKANVTHPELGVTVQLPIISVKKNPQNPLYTQLGVLTKGTILEVNVSELGLVTAGGKVVWGRYAQVTNEPENEGCVNS Umbra1 NEYIEKRHGRRLDYAERKRKREAREVHKNSQYAQGLKAKKRHSEKIQMKKTIKQHEEKNAKG-AVPTYLLDREAKILSNMVKQKRKEKAGKWNVPLPKVRGIAEDEMFKVVKTGKN-KTKSWKRLVTKATFVGEGFTRKPPKYERFVRPMGLRYKKAHVTHPELKATFQLPIISVKKNPQNPLYTQLGVITKGTVIEVNVSELGLVTTGGKVVWGKYAQVTNNPENDGCINA Ustma22 NDYIERRHGRRLDHEERQRKRAAREVHKASAVAQGLKAKKRRNEKIQMKKTLKAHEERDVKQ-ALPTYLLDREAKALSSAVKERRKDKAARYSVPLPQVRGIAEDEAFKVIKTGKR-KQKGWKRMVTKPTFVGESFTRKPPKLERFIRPMGLRYNKAHVTHPELKASFNLPIVGVKKNPQSPLYTQLGVLTKGTIIEVNVSELGMTTTTGKVVWGKYAQVTNNPENDGCVNA Walse1 NEYIERRYGKRLDHDEKLRKKEARSVHQNSKLARGLKAKQKHAEKVQMKKTMKNHSERNVKA-ALPTYLMDRNAKSISSAIKQKRKDKAARFSVPLPKVRGIAEEEVFKVIKTGSK-KQKSWKRMITKPTFVGENFTRKPPKLERFIRPSGLRMKKANVTHPELKTTFQLPIIGVKKNPQSPLYSQLGVLTKGTVLEVNVSELGMVTTGGKVVWGKYAQITNNPENDGCVNA Zygro1 NEYIEKQHGRRLDHEERKRKKEAREVHKVAERAQGWRGKKRYAEKVAMKKRIKAHEQSKVKGEALPAYLLDREAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKAVKTGKS-KSKSWKRMITKPTFVGEGFTRRPVKMERIIRPTALRQKKANVTHPELKVTVFLPILSVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTSGGKVVWGKYAQITNEPDRDGCVNA [Cluster1614.fasta_al_trimmed; alignment length = 117] Allma1 ERAFQKQ-HIFKDVGLGFKTPKEAIEGHYIDKKCPFTGN-VSIRGRILTGTIVSAGKMKRTIILRREYLHYVKKYNRYEKRHRNLAAHMSPCFNGDLATVGQCRPLSKTVRFNVLKI Ashgo11 ERAFQKQPHIFKNAGLGFKTPKTAIEGSYIDKKCPFTGL-VSIRGKILTGTVVST-KMHRTIIIRRDYLHYVPKYNRYEKRHKNVPVHVSPAFLGDIVTVGQCRPISKTVRFNVLKV Aspfu1 ERAFQKQPHIFKDVGLGFRTPKTAIEGSYIDKKCPFTGM-VSIRGRILTGRVVST-KMHRTIIIRREYLHYVPKYNRYEKRHKNLAAHVSPAFEGDWVTVGQCRPLSKTVCGN---- Aurde31 EKAYQKQH-LFKDVGLGFKTPGEAITGTYIDKKCPFTGS-VSIRGRILTGKVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFVGDIVTVGQCRPLSKTVRFNVLRV Batde5 EKAFQSQAGMFNDVGLGFKTPTEAIKGHYIDKKCPFTSSSVSIRGRILTGVVMST-KMKRTLIIRREYLHYIKKYNRYEKRHKNLAAHVSPAFAGDTVTVGQCRPLSKTVRFNVLKV Botbo1 EKAYQKQH-LFKDVGLGFKTPSEAIKGTYVDKKCPFTGD-VSIRGRILTGKVIST-KMTRTIIIRRDYLHFIPKYHRYEKRHKNLAAHVSPAFIGDTVTVGQCRPLSKTVRFNVLRV Botci1 ERAFQKQPHIFKDVGLGFRTPKTAIEGSYIDKKCPFTGL-VSIRGRILTGTVVST-KMHRTLIIRREYLHFIPKYARYEKRHKNLAAHVSPAFEGDQVTVGQCRPLSKTVRFNVLRV Caeel ERAFLKQPTVNREVGLGFKAPRDAVEGTYIDKKCPWAGN-VPIRGMILTGVVLKN-KMTRTIVVRRDYLHYIKKYRRYEKRHKNVPAHCSPAFPGDLVTIGECRPLSKTVRFNVLKV Canalb1 ERAFQKQPHIFKDVGLGFKTPKAAIEGSYIDKKCPFAGT-VSIRGKILTGTVVST-KMHRTIIIRRDYLHYVPKYNRYEKRHKNVAAHVSPAFEGDVVTVGQCRPISKTVRFNVLKV Cangl ERAFQKQPHIFKNAGLGFKTPKTAIEGSYIDKKCPFTGL-VSIRGKILSGTVVST-KMHRTIIIRRDYLHYVPKYNRYEKRHKNVPVHVSPAFVGDIVTVGQCRPISKTVRFNVLKV Capow EKAFQKQPTIFRNVGLGIKTPREAIEGNYVDKKCPFTGD-VSIRGRILTGVIANN-KMKRTITVRRDYLHYIKKYNRFEKRHRNLSAHISPAFVGDSVVVGQCRPLSKTVRFNVLKV Catan2 ---------------------------------------------------------MKRTVILRREYLHYVKKYNRYEKRHRNLAAHLSPAFNGDVATVGQCRPLSKTVRFNVLKI Cioin ERAYQKQPTVFRSIGLGFKTPREAFEGNYIDKKCPFTGN-VLIRGRILTAVVTKL-KMQRTCVVRRDYLHYVRKYNRFEKRHQNMSVHISPCFPGDIATIGECRPISKTVRFNVVKI CocheC53 ERAFQKQPHIFKDVGLGFRTPKTAIEGTYIDKKCPFTGM-VSIRGRILTGTVMST-KMHRTLIIRREYLHFIPKYSRYEKRHKNLAAHVSPAFPGDQVVVGQCRPLSKTVRFNVLRV Coere1 ERSFQKQASVFKDIGLGFKTPVTAINGTYVDKKCPFTGD-VSIRGRILSGTVHST-KMTNTIIVRREYLHYIPKYQRYEKRHKNIAAHLSPAFKGDIVTVGQCRPLSKTIRFNVIKH Conco1 ERSFQKQTGVFKDVGLGFKTPKEAIEGTYIDKKCPFTGN-VSIRGRVLTGVVVST-KMKRTLIVRREYLHYIPKYNRYEKRHKNLAAHVSPAFNGDMVTVGQCRPLSKTVRFNVLKV Conpu1 EKAFQKQH-LFKDVGLGFKTPSEAIQGTYIDKKCPFTGA-VSIRGRILTGKVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFVGDVVTVGQCRPLSKTVRFNVVRV Copci EKAFQKQH-LFKDVGLGFKTPSEAINGTYIDKKCPFTGN-VSIRGRILTGKVVST-KMIRTIIVRRDYLHYIPKYNRYEKRHKNLAVHISPAFVGDTVTVGQCRPLSKTVRFNVLRV Croqu1 EKAFQKQP-IFKNVGLGFKTPAEAINGTYIDKKCPFTGE-VSIRGRILTGRVVST-KMTRTIIIRREYLHFVPKYSRYEKRHQNMAVHCSPAFIGDQVTVGQCRPLSKTVRFNVLRV CryneH991 EKAFQKQH-LFKDVGLGFKTPNEAINGTYIDKKCPFTGD-VSIRGRILNGIVHST-KMTNTIIIRREYLHYIPKYRRYEKRHKNLAAHCSPAFIGDQVTVGQCRPLSKTVRFNVVRV Crypa2 ERAFQKQPHVSKDVGLGFRTPKAAIEGQYIDKKCPFTGL-VSIRGRILTGTVVST-KMHRTIIIRREYLHFIPKYSRYEKRHKNLAAHVSPAFEGDQVTVGQCRPLSKTVRFNVLRV Debha1 ERAFQKQPHIFKEVGLGFKTPKAAIEGNYIDKKCPFAGS-VSIRGKILTGTVVST-KMHRTIIIRRDYLHYVPKYNRYEKRHKNLAAHVSPAFEGDVVVVGQCRPISKTVRFNVLKV Dekbr2 ERAYLKQPHIYKDIGLGFKTPKTAIEGTYIDKKCPFTGL-ISIRGRILSGTVVST-KMHRTIVIRRDYLHYIPKYNRYEKRHKNVAAHVSPCFEGDNVTVGQCRPLSKTVRFNVIKV Dicdi EKAFQKQQVSFKNIGLGYRTPKDAIEGTYIDKKCPFTSD-VSIRGAILRGTVIST-KMRRTLVVRRNYLHYIKKYNRFEKRHSNIPAHVSPAFEGDSVTIGQCRPLSKTVRFNVIKH Dmel ERAFQKQFGVNRDVGLGFKTPREAIDGTYIDKKCPWTGD-VRIRGRILTGVVRKA-KMQRTIVIRRDYLHFVRKYSRFEKRHRNMSVHCSPVFHGDIVTIGECRPLSKTVRFNVLKV Enthi ERAYQKQ--VFKQIGMGFVTPAEAIKGTYIDKKCPFTSD-VSIRGRTLSGIVKSC-HMKRTIIVRRDYFHYVSKYQRYEKRHKNIAVHCSPAFEGDHVVIGQCRPLSKTVRFNVLKF Falba EKAFQKQHGISKNVGLGIRTPTEAIKGNYIDNKCPFTSD-VSIRGRILSGVVAST-KMNRTITVRRDYLHYVRKYSRYEKRHRMISAHCSPAFEGDIVTVGQCRPLSKTVRFNVIRI Fomme1 ERAYQKQH-LFKDVGLGFKTPLEAINGTYIDKKCPFTSD-VSIRGRILTGKVVST-KMNRTIVIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFLGDMVTVGQCRPLSKTVRFNVLRV Fusgr1 ERAFQKQPHIFKDVGLGFRTPKTAIEGSYIDKKCPFTGL-VSIRGRILTGTVVST-KMHRTIIIRREYLHFIQKYSRYEKRHKNVAAHVSPAFEGDQVTVGQCRPLSKTVRFNVLRV Galma1 EKAFQKQD-IFKDVGLGFKTPSEAINGTYIDKKCPFTGD-ISIRGRILTGKVMST-KMNRTIIIRRDYLHYIPKYNRYEKRHKNLAAHLSPAFIGDVVTVGQCRPLSKTVRFNVLRV Ganpr1 ERAFLKQDAVFKEVGLGFKTPKEAKEGTYVDKKCPFTGD-VSIRGRILTGVVRST-KMKRTIIIRRDYLHYIAKYNRYEKRHRNLAAHLSPCFVGDVVTVGQCRPLSKTVRFNVLRV Gloin1 ERAFQKQPNIFKDVGLGFKTPKEAIEGHYIDKKCPWAGM-VSIRGRILNGVVVST-KMKRTIIVRREYLHYIKKYNRYEKRHRNVAAHLSPAFPGDTVTMGQCRPLSKTVRFNVLKV Hisca1 ERAFQKQPHIFKDVGLGFRTPKTAIEGSYIDKKCPFTGQ-VSIRGRILTGTVVST-KMHRTIIIRREYLHYIPKYSRYEKRHKNIAAHVSPAFEGDQVTVGQCRPLSKTVRFNVLRV Klula1 ERAFQKQPHIFKNVGLGFKTPKTAIEGSYIDKKCPFTGL-VSIRGKILTGTVVST-RMHRTIVIRRDYLHYVPKYNRYEKRHKNVPAHVSPAFVGDIVTVGQCRPISKTVRFNVLKV Lacbi2 EKAFQKQN-LFKDVGLGFKTPSEAINGTYIDKKCPFTGD-ISIRGRILSGKVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLAAHASPAFVGDVVTVGQCRPLSKTVRFNVLRV Lenti61 EKAFQKQP-IFKDVGLGFKTPAEAINGSYVDKKCPFTGE-VSIRGRILTGRVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFVGDVVTVGQCRPLSKTVRFNVVRV Malgl1 ERAFQKQP-LFKDVGLGFKTPSAAVSGTYIDKKCPWTGL-VSIRGRLLSGKVIST-KMTRTVIIRREYLHYVSKYNRYERRHKNLAVHVSPAFVGDIIVAGQCRPLSKTVRFNTLKV Mellp23 EKAFQKQP-IFKNVGLGFKTPTEAINGTYIDKKCPFTGE-VSIRGRILTGRVVST-KMTRTIIIRREYLHFVPKYSRYEKRHQNMAVHCSPAFIGDQVTVGQCRPLSKTVRFNVLRV Mnele --------------------------------------------------------------------------------------------------------------------- Monbr ERSYLKQKPIFKSVGLGFKTPKEARELKYIDKKCPWTGD-VSIRGRLLTGVVKTL-KMQRTGIIRRDYLHYIKKYNRFEKRHKTLPVHVSPCFVGDQVTVGQCRPLSKTVRFNVLRI Morel2 EKAFQKQQGIFKEVGLGFKTPKEAIEGHYIDKKCPFTGD-VSIRGRILTGEIIST-KMKRTIIIRREYLHFISKYNRYEKRHKNLAAHMSPAFQGDSVTVGQCRPLSKTVRFNVLKV Mucci2 EKAFQKQAGIFKEVGYGFKTPKEAKTGTYIDKKCPFVGE-VNIQGRILTGIVTST-KMKRTLVVRRDYLHYVPKYNRYEKRHKNISAHVSPAFAGDVVTIGQCRPLSKTVRFNVLKV Mydma ERAFQKQPAIFRNVGLGFKTPREAIEGTYIDKKCPFTGN-VSIRGRILTGIVKSL-KMKRTIVIRRDYLHFIKKYQRYEKRHKNLVAHMSPCFLGDLVTVGQCRPLSKTIRFNVLKV Neucr2 ERAFQKQPHIFKDVGLGFRTPAAAIEGQYIDKKCPFTGQ-VSIRGRILSGTVVST-KMHRTIIIRREYLHFIPKYNRYEKRHKNLAAHVSPAFEGDKVTVGQCRPLSKTVRFNVLRV Orpsp11 --------------------------------------------------------------------------------------------------------------------- Pench1 ERAYQKQPHIFKDVGLGFRTPKTAIEGTYIDKKCPFTSQ-VSIRGRVLVGKVVST-KMHRTLVIRREYLHYVPKYNRYERRHKNLSAHVSPAFEGDMVTVGQCRPLSKTVRFNVLKV Phybl2 EKAFQKQAGIFKDVGLGFKTPKEAKSGSYIDKKCPFTGE-VNVQGRILIGVVVST-KMKRTIVVRRDYLHYVPKYNRYEKRHKNISAHLSPAFSGDIVTIGQCRPLSKTVRFNVLKV Picst3 ERAFQKQPHIFKDIGLGFKTPKTAIEGTYIDKKCPFVGT-VSIRGKILTGTVVST-KMHRTIIIRRDYLHYVPKYNRYEKRHKNVAAHVSPAFEGDVVTVGQCRPISKTVRFNVIKV Plicr1 EKAYQKQH-LFKDVGLGYKTPQEAISGTYIDKKCPFTGD-VSIRGRILTGKVVST-KMTRTLIIRRDYLHYIPKYNRYEKRHKNLAAHVSPAFVGDVVTVGQCRPLSKTVRFNVLRV Polpo EKAFQKQLCVFKSIGLGYRVPKDAIDGTYVDKKCPFTSN-VSIRGTILKGVVVST-KMRRTIIMRRDYLHYIKKYNRFEKRHSNISAHASPAFDGDSVTIGQCRPLAKTVKFNVIKH Pucgr2 EKAFQKQP-IFKDVGLGFKTPAEAINGTYIDKKCPFTGE-VSIRGRILTGVVVST-KMTRTIIIRREYLHYIPKYSRYEKRHQNMAVHCSPAFIGDQVTVGQCRPLSKTVRFNVLRV Punst1 EKAYQKQH-LFKDVGLGFKIPSEAITGTYIDKKCPFTGN-VSIRGRILTGRVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLSVHCSPAFLGDIVTVGQCRPLSKTVRFNVLRV Rhior3 EKAFQKQAGIFKEVGNGFKTPKEAKVGTYIDKKCPFVGE-VNIQGRILTGVVVST-KMKRTLVVRRDYLHYIPKYNRYEKRHKNISAHVSPAFVGDMVTIGQCRPLSKTVRFNVIKV Rhoto1 --------------------------------------------------------------------------------------------------------------------- Rozal11 EKAFQKQVGIFKDVGLGFKTPAEAINGHYIDKKCPFTGD-VSIRGRILTGVVVST-KMKRTIILRREYLHYITKYNRYEKRHKNLAAHLSPCFNGDVVTVGQCRPLSKTVRFNVLKV Sacce1 ERAFQKQPHIFKNAGLGFKTPKTAIEGSYIDKKCPFTGL-VSIRGKILTGTVVST-KMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFVGDIVTVGQCRPISKTVRFNVVKV Salro ERAYQKQRLIFKNVGLGFKTPREARELEYIDRKCPFTGD-VSIRGRVLNGVVKTL-KMQRTCVVRRDYLHFIPKYRRFEKRHKNLSVHVSPAFVGDAVTIGQCRPLSKTVRFNVLRV Schco3 EKAFQKQP-LFKDVGLGFKTPTEAINGSYIDKKCPFTGL-VSIRGRILTGKVVST-KMTRTIIIRRDYLHYIPKYNRYEKRHKNLAAHLSPAFVGDVVTVGQCRPLSKTVRFNVLRV Schpo1 ERAFQKQPHIFKDVGLGFKTPAEAIYGEYVDKKCPFVGQ-VSIRGRILTGTVVST-KMHRTIIIRREYLHFIPKYNRYEKRHKNLAAHVSPAFEGDVVTVGQCRPLSKTVRFNVLRV Sorma ERAFQKQPHIFKDVGLGFRTPAAAIEGQYIDKKCPFTGQ-VSIRGRILTGTVVST-KMHRTLIIRREYLHFIPKYNRYEKRHKNLAAHVSPAFEGDQVTVGQCRPLSKTVRFNVLRV Sphar EKAFQKQPTIFRNVGLGIKTPREAYDGHWVDKKCPFTGD-VSIRGRILNGTIVSM-KMQRTVVIRRDYLHYIKKYQRYEKRHSNLSAHMSPAFVGDSAVVGQCRPLSKTVRFNVLRT Spipu1 QKAFQSQIGIFKDVGLGFKTPREAIEGHYIDKKCPFTSDKVSIRGRILTGVVISVGKMERTIIIRREYLHYIPKYNRYEKRHKNLAAHMSPCFVGDVVTVGQCRPLSKTVRFNVLRV Sporo1 EKSFQKQP-LFKEVGLGFKTPREAIEGTYIDKKCPFTGL-VSIRGRILTGKVVST-KMTRTIVIRREYLHFVPKYSRYEKRHKNVAVHCSPAFVGDVVTVGQCRPLSKTVRFNVLRV Stehi1 EKAYQKQH-LFKDVGLGFKTPAEAVSGTYIDKKCPFIGD-VSIRGRILTGRVVST-KMTRTLVIRRDYLHYIPKYNRYEKRHRNLAAHVSPAFVGDIVTVGQCRPLSKTVRFNVVRV Tapde11 QSAFQKQPHIFKEVGLGFKTPREAINGEYIDKKCPFVGD-VSIRGRILTGTVVST-KMARTVVVRREYLQFVPKYRRYEKRHKNLSAHASPAFDGDIVTVGQCRPLSKTVRFNVLRV Thetr ERAFQKQPHITKDIGLGFVTPREAIEGSYIDKKCPFTGN-VSIRGRILDGVVVST-KMRRTCIIRRDYLHYVKKYNRFEKRHTNTACHVSPCFEGDRVVVGQCRPLSKTVRFNVIKV Treme1 EKAFRKQK-IFKDVGLGFKTPQEAINGTYIDKKCPFTGE-VSIRGRILTGVVHST-KMTNTIIIRREYLHFVPKYRRYEKRHKNLAAHCSPAFQGDTVTVGQCRPLSKTVRFNVLRV Trire2 ERAFQKQPHIFKDVGLGFRTPKTAIEGSYIDKKCPFTGL-VSIRGRILTGTVVST-KMHRTVIIRREYLHYIPKYSRYEKRHKNLAAHVSPAFEGDQVTVGQCRPLSKTIRFNVLRV Umbra1 EKAFQKQAGVSKDVGLGFKIPKEAIEGTYIDKKCPFTGD-VSIRGRILTGVVVST-KMKRTVVIRREYLHYIPKYSRYEKRHRNLSAHMSPAFAGDIVTVGQCRPLSKTVRFNVLKV Ustma22 EKAFQKQP-IFKDVGLGFKTPRAAIDGTYIDKKCPWTGL-VSIRGRILTGKVVST-KMTRTIIIRREYLHFVPKYSRYEKRHKNVAAHVSPAFVGDTVTIGQCRPLSKTVRFNVLKV Walse1 LKTFPKQP-IFKDVGLGFKTPQEAVTGTYIDKKCPWTGE-VSIRGRILTGKVVST-KMTRTIVIRREYLHYVPKYNRYEKRHKNLPVHASPAFVGDQVVVGQCRPLSKTVRFNVLRV Zygro1 ERAFQKQPHIFKNAGLGFKTPKTAIEGSYIDKKCPFTGM-VSIRGKILTGVVVST-KMHRTVIMRRDYLHYVPKYNRYEKRHKNVPVHVSPAFVGDIITAGQCRPISKTVRFNVVKV [Cluster1626.fasta_al_trimmed; alignment length = 237] Allma1 LLDSHNTILSLKLQIADFDGAKFYAATESDNK--AVVHVSLRCYAELAAGANEFLASIYGDMLDNGYDVTLRIDLDAVTERVLTDVPLLKRHAMAALFHKAFLHYRD-GEAFYVQAQPDRVTVIFATQFK--EETDRVFA-KVFLQE-FVDARRQNAPAVLYSARDP-PLELRSVGYVTFILFPRHTISRIQLFRDFLHYHIKCSKAYMHSRMRARVDSFLKVLNRAKPEEKKTASG Ashgo11 HLQPHNLLITLDRVVSDFDYATFHISNADQTG--VTLNVSTKAWQSVAAGLLAYLQDKYDRLPETGYDHTLLIQLDALAPESVMQVALLKMTTMAYVFQLAFIQYRD-DENIYIKPSGDRVTVIFETMFQ--GETDKVFG-KVFLQE-FVDARKQSAPQVLVSH-EA-PLEIASKRFVTFVLFPRHSVCHLALFRNYFHYHIKCSKAYMHTRMRRRVDSFIKVLNRAKVD-RRTISG Aspfu1 LLDYQNVLISIDQVVSDFDGVTFHLST-PESK--TKILISVKCFKELVQGAQEVLEREYGPYIEPGYDFSVQIDLENLRDELIMRLALLKRNAMAAPFERAFIHYRE-EEAIYIKASHDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLFRS-DP-PLELQKMSYVTFVLFPRHNISHIQTFRDYFHYHIKASKAYIHTRMRKRTADFLQVLNRARPEERKTASG Aurde31 LLETHNTIISLDEHFVDYDGVRFRLST-PERK--TLLRLSIRCWDELAQGARDILAREYGTYLEPEYSVTLEFDTEKVREALIKSASLLKRIALGAPFETAFIHYRD-EEAIYVQAQADRVTVVFSTVFR--EEADRIFG-KVFLQE-FVDARRQTAPQVLFSAKEP-PLEIRDVGYVTFVIFPRHTISHIQLFRSYLHYHIKCSKAYMRSRMRHRVAEFQKILNRAKTEERKTVSG Batde5 LLEPHSKILRCQITLADFDGVIYRIST-PESK--TVLLISIRCYAELERGAASILKREYGQYFEPGYDVSLTIDLTTLREPLIRAISLLKRNIMAAAFEAAFIHYRD-DEAIYVKALPDRVTVIFSTEFK--DETDKIYG-KVFLQE-FVDARRQNAPQVLYSAREP-PLELRTVGYVTFVLFPRHAISRIQLFRDYFHFHIKASKAYMHSRMRARVDNFLKVLNRAKPEEKKTASG Botbo1 LLESHSVIISIDVQFVDYDGVRFHLST-PQRK--TLLLLSIRCWEELVQGAMDVIKREYGSYFEPEYNVSLEFDLEAIREAIIKSASLLKRNVLGAPFELAFIHYRD-EEAIYIQASQDRVTVVFSTVFK--DETDRIFG-KVFLQE-FVDARRQNAPQVLYSNKEP-PLEIRDVGYVTFVLFPRHTISRIQEFRDYLHYHIKCSKAYMHSRMRHRVTEFLKVLNRAKTEERKTVTG Botci1 LLDYQNVLINIDQTVADFDGVTFHIST-PEAK--TKILVSVKCYDELVRGAQQVLEREYGPFVESGYNFSVQVDLESLRDDLIRRISLLKRNAMAAPFEHAFIHYRD-EEAIYIKASHDRVTVIFSTVFR--EETDRVFG-RVFIQE-FVDARRQNAPQVLFRT-DP-PLELQDIGYVTFVLFPRHVISHIQTFRDYFHYHIKASKAYIHSRMRTRTADFLQVLRRARPEERKTATG Caeel ILEQNNRIISVNVTFADFDGVLYKLSN-PDGD-RTKIILSLKFYTELQQGADDLLRRVYGGHMEQGFNVTLEYNLADLTTDLVQAASALKRNCFASVFEKYFINYRD-DETMYIEAKADRVTVIFSTVFK--DADDVIIG-KVFLQE-FREGRKQTAPAVLYSLGEP-PLELKNVGYITFVLFPRHTIDLIHSFRDYLHYHIKCSKVYLHTRMRAKTTDFLKVLNRARPEEKKTFHG Canalb1 HIEQNNLLISLDRIVSDFDFTTFHLSTLPGEK--HLLLISLRCWPDLVKDVVKYLNDKYQPFNEQGYDYSLVLDTSTAKLQLIKELSNLKRNAMAAPFEQAFIKYRGIDECIYLKPSFDRVTVIFSTVFQ--DETDKIFG-KVFLQE-FVDARKQTAPQVLYSHIEP-PLDIQNYGYVTFVLFPRHCISHIELFRSYFHYHIKCSKAYMHSRMRFRVKEYLKILNRAKPENRKTASG Cangl HLQPANLLITLDRIISDFDYTTFHVSNTPDNK--SILLLSTKAWQSILQDLLTFLQGKYANTQEPGFDYTLQIDIGSLNEEAIKRCSILKTLVLSFPFHQAFIKYRD-DENIFVKAASDRVTVIFETIFQ--DETDKILG-KVFLQE-FVDARKQSAPQVLFSH-EP-PLEIQSRRFITFVLFPRHSVSQLTLFRNYFHYHIKCSKAYMHSRMRYRVDTFVKVLNRAKVD-RRTITG Capow LLEFQNRIISIDLTVADFDGVTFHISS-TGEN-KSVVQVSIRCFAELQAGADEYLKKVYGSNVENGYSFTIALDFDKLKDEVINDFALLKRHCLAAPIGKYFISYRE-DEKIYLNAEKDRVTVVFSVRFR--DADDVVLG-KVFLAE-FVDARKNQAPQVLF-SKEP-PREIANMSYVTFVLFTRHSISLVQTFRDYLHYHIKCSKAYLHSRMRARVTSLLKILNRARPEERKTATG Catan2 LLDNHHQIL-------------------PA----ITLILSAPRTSDLARGARDVLAKTFADLLEQGYDVTL---------------------RMAAPFHAAFIHFRE-GEAIYIQAMPDRVTAIFATQFK--DETDRIFA-KVFLQE-FADARRMNAPAVF---------------------IPQHTISRIHLFRDYLHYHIKCSKA--------------------------TAV- Cioin LLETENRVISIEVTVADFDGAVYHLSN-PDGD-KTKIRVSLKFYKDLQDGADELLRREYGAYYEDGFSVTLVYDLTSVYKPIAKKASLLKRNCFASVFEKYFIHYRD-DETMYVESKKDRVTVIFSTVFK--DESDVTFG-KVFMQE-FKESRRQTAPQVLYNHKEP-PMELSNIGYVTFVLFPRHTIDLIHTFRNYLHYHIKCSKAYMHQRMRAKTSDFLKVLNRARPEEKKTMSG CocheC53 LLDYQNVLINIDQVVSDFDGVTFHIST-PETK--TKILVSIKCFKELVQGAQAVLEREYGPFIESGYDFSVLVDLENLKDDLVRRVALLKRNAMAAPFEQAFIHYRE-EEAIYVKASHDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLFRN-DP-PLELQDIGYITFVLFPRHVISHIQTFRDYFHYHIKASKAFIHSRMRKRTADFLQVLRRARPEERKTASG Coere1 LLEPNSRVLIVEITLVDFDNVVYHVQTSAEQR--TLLNLSY--FNEVLSGADEILKREYGDYLNPQYQITLQFNLEQLKTALARHVSMLKRNMLASSFIRAFTHYRD-SEAIYVQAQQDRVTVIFSTLFK--EEVDRVLG-KVFLQE-FVDARRQNAPQVFYSSREP-PLEIRSVGYVSFVLFPRHTISQIQLFRDYLHYHIKCAKAYMHSRMRTRVKEFLKVINRAKPDEKRTATG Conco1 ----------------------------------------WSCFHQLKSDVDSLLKSKYNDYLEQQFDVTLKFDLNNLTDDLLKEIGQLKRNALAAPFVLAFVNYRE-GEAIYVHSQADRVTVIFTITFK--EEMDRVFG-KVFLQE-FVDARRQNAPQVIYSSRDP-PGELKDIGYVTFVIEPRHTINLIQLFRDYLHYHIKCSKAYMHSRMRSRVSEFLKVLTRAKPEEKKTATG Conpu1 LLEAHNVIISLDVQFVDFDGVRFRMST-ADRK--TVILLSIRCWDELVKGAMDVLQREYGNLIEAEYNVSLSIDLEQARDAFVRSISMFKRNALAAPFESAFIHYRD-EEAIYVQASPDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSSRDP-PLEIRDIGYVTFVLFPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRHRVAEFQKVLNRAKTEERKTVTG Copci LLESHNVIISLDVQFVDYDGVRFHLST-PEKK--TQLLLSIRCWDELVQGALDVLGREYGSLLEPEYNVSMAIDLEQVRDAFIMSIALFKRHALAAPFELAFIHYRD-EEAIYIQAAHDRVTVIFSTVFQ--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSSRDP-PLEIRDVGYVTFVLFPRHSISHIQLFRDYLHYHIKCSKAYMHSRMRHRVTEFQKILNRAKTEERKTVSG Croqu1 LLEDHNKIISLDQAFVDFDGVRYHLST-PNKK--SIILLSVKCWPQLIEGVLEIMKREYSNWIEVDYDISLIFEIDKLRSNLIKSVALLKRNALAAPFERAFLNYRP-EEAIYVIPNIDRVTVVFSTVFR--EDTDMVYG-KVFLQE-FVDARRQTAPQILYSNREP-PREISNMGYVTFVLFPRHTISRIQLFRDYLHYHIKASKAYIHSRMRARTNEFLKILNRAKPEERKTASG CryneH991 LLESHNTIIRADIQFVDYDNVRFHLST-PSSK--TQLLLSIQCWPDLVKGAREHLQNEYQGYFEPEYDVSLLIDLERLRAALISKVAHIKSTAMSSPFLAAFVKYRE-EEAIFIQASHDRVTIIFSTVFK--EETDRVYG-RVFLQE-FVDARRQNAPQVMYSNREP-PLEIRDWGYVTFVLFPRHTINRIQLFRDYLHYHIKCSKAYMHSRMRYRVAEFLKVLNRAKPEEKKTASG Crypa2 LLDYQNVLISIDQTVSDFDGVIFHIST-PEVK--TKILVSIKCYRDLVKGAEQVLNREYGEYVEPGYDFSILIDLENLRDELVKKVSLLKRNAMAAPFEHAYIHYRE-EEAIYVKSSHDRVTVIFSTIFR--EETDRVFG-KVFIQE-FVDARRQNAPQVLFRT-DP-PLELQEVGYVTFVLFPRHVISHIQTFRDYFHYHIKASKAYIHSRMRRRTADFLQVLRRARPDERKTASG Debha1 QIEHNNLLISLDRIVSDFDFTTYHISTLPDNR--ELILISLKCWSDLVNGVEAYLGNKYSKYEESNYNYSMVLDLSQLKNQLIEDLSFLKRHCMAAPFEQAFINYRGSDESIYIKPSFDRVTVIFSTIFK--DETDKIFG-KVFLQE-FVDARKQNAPQVLYSHKVP-PLDIQNKGYVTFVLFPRHCISHIQFFRNYFHYHIKCSKAYMHSRMRFRVKEFLKVLNRAKPENRKTASG Dekbr2 SLQPENLLISLDRIITDYDFTAYHIST-PKEK--TAILLSIKCWDDLVQGTLDLLESIYSKYSEPGYNYSLYVDLSKVKSALISELSLLKRNCFAAPFLETFLHYRD-NESIFIKPSNDRVTVIFSTIFS--DETDKVFS-KVFLQE-FSDSRRQKAPQVINSHHEI-PLEIQKKTYITFVLFPRHTITQIELFRSYFHYHIKIVKCYLHQRMRFRVQSFTKILNRARRDERKTASG Dicdi LLETHNRILRVNNIFADFDGVKFNVQT-SDDK--SSLMVSLHAAADLLKGGSALLKSVYGDMLEGGYDVTLVIQSSFSKEELAKKVSLLKRHLVAAPFLMVFINYRT-DETFYLKPQGDNVIVIFDIAFK--DADDVILS-KIFLQS-FVDVRKSNVPSITFSQKDP-PLELKNHGFVSFVLFPAHSADLIQTFRDYLHYHIKCAKGYMHTSMRNRVESLIQVLNRAKPEVKRTITG Dmel LLEINNRIISIDIRIADFDGVLYHISN-VNGD-KTKVRISLKFYKQLQEGADELLKREYGSLLEEGYNVSVLINLEEICEQIAKRIGLLKRNCFASVFEKYFINYRN-DETLYVEAKPDRVTVVFSTIFR--DEDDVIIG-KVFMQE-LREGRRHTAPQVLFSHREP-PLELANIGYVTFVLFPRHTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPEEKKTITG Enthi LLESYNRIVGLKEKLADFNQSIWYIER-TKEK----MTISTPCWKQLKERSLEFLQKVYGSDLNSEYNLILTI-----PEEFAMNAAKLLTNMLIGPAVVLAIDYRP-GESYWLKPNGDRLTVIFSIKFD--DKDDAVFG-RVFINE-FSKSAAKNAP--------P-PSELKDNCYISFLLEKRHTLEVLMSCRNYINFHIKCSKAFLHIRMRNKVSHLQLVLNRAKPEEKKTASG Falba LLEYGNLVLSLSHNFADFDGVQFNLAT-ENTD-RNVVYLSWRCFSELASNAVSHLEKIYGPLVRPGYDFTLAFNMSQLRDELIENLSLLKRHALAVPFERAFISYRN-EESIWIKTDKDRVTVIFSVTFK--DPADIVFG-KVFLQE-FVDARRQNSPQVIFYPEDA-PAELTSIGYVTFVLFPRHTISLIQTFRDYLHYHIKCSKAYMHSRMRARVTAFLQVLNRAKPEDKRPAAA Fomme1 LLEAHNHIIALDIQFVDYDGVRFHLST-PQVK--TTLLLSIRCWNELAQGALDVLKREYGGLLEPEYNLSLEIDLTQARDSFVKSLALLKRNVLAAPFERAFIHYRD-EEAIYIQAAPDRVTVFFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSNRDP-PLELRDIGYVTFVLFPRHTISHIQLFRDYFHYHIKCSKAYMHSRMRFRVSEFQKILNRAKMEERKTVSG Fusgr1 LLDYQNVLISIDQTVSDFDGVTFHIST-PETK--TQVLLSIRCFPDLVKGAEEVLQREYGDYVEPGYDFSVLVDLENLRNELALKFALLKRNAMAAPFEQAYIHYRE-EEAIYVKASHDRVTVIFSTVFR--EETDRVFG-KVFIQE-FVDARRQNAPQVLFRN-DA-PLELQDIGYVTFVLFPRHVISHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPEERKTASG Galma1 LLEPHNAIISLDVVFVDYDNVRFHLST-PERKTVTVLLLSIRCWDELVQGALDILRREYGSLLEPDYNVSLEIDLEQAREAFVMSLSLLKRNALAAPFERGFIHYRD-EEAMYIQAAPDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSSRDP-PLEIREIGYVTFVLSPRHTISHVQLFRDYLHYHIKCSKAYMHSRMRHRVTEFQKVLNRAKTEERKTASG Ganpr1 LLEYANRIITTSLNIADFDGVGYRLST-PESK--TLLVVSMPCFGELLQGAMDVLRREYGSMLEPGFEVTLKVDIEKVREALIRKIALLKRNALAAPFEQAFIHYRD-TEVFYVKAGTDRVTVIFSTEFK--EEQDRILG-KVFLQE-FVDARRQNAPQVLYTNRDP-PLELRNIGYVTFVLFPRHTISKIQLFRDYLHYHIKCSKSYMHSRMRARVAEFLKVLNRAKPEEKKTIAG Gloin1 LLDYHNVVIVLDMTVVDFDGVAYHLST-PESK--SVIKFSMQCYKELVQGAQDMLQREYGPYCEDGYDVTLEFDLQKLREELVKKLALIKRNLMAQPFERAFIHYRD-QEAIYIQAQLDRVTVIFTTLFK--EETDRIFG-RVFLQE-FVDARRQNAPQVLYSSKEP-PLEIRDIGYVTFVLFPRHTISQIQLFRDYLHYHIKCSKAYMHSRMRARVQEFLKVLNRAKPEEKKTITG Hisca1 LLDYQNVLISIDQIVSDFDGVTFHIST-PEAK--SKILISLKCFRELVQGAQSVLEREYGPFIEPGYDFSIVVDLENLREDLVNRIALMRRNVMAAPFEKAFIHYRE-QEAIYIKASHDRVTVIFSTIFR--DETDRIFG-KVFLQE-FVDARRQNAPQVLFRH-DP-PLELQDVGYITFVLFPRHNISHIQIFRDYFHYHIKASKAYIHSRMRRRTADFLQVLNRARPEERKTASG Klula1 HLKPYNLLVTLDRIISDFDYTTLHITNDGTDK--SNLLVSTKATQSCNEDLQGFLQAKFDEVPEAGYDFTITVDLSQITAQSIVQASLFKILVMSYPFYLAFIKYRD-DENIYIKPSFDRITVIFETIFQ--DETDKVFG-KVFLQE-FVDARKQSAPQVLFSH-EP-PLEIQTRRFITFVLFPRHSVSQLALFRNYFHYHIKCAKAYMHSRMRYRVDTFIKVLNRAKLD-RRTITG Lacbi2 LLEPHNVIISLDVQFVDYDGVRFHLTT-PERK--TSLLLSIRCWDELVRGAMDVLKREYGALLEPEYNVSLEIDLEQVRDDFVMSIALFKRNALAAPFELAFIHYRD-EEAIYVQAAHDRVTVIFSTVFQ--EETDRIFG-RVFLQE-FVDARR-NAPQVLYSNRDP-PLEIRDIGYVTFVVSPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRHRVTEFQKILNRAKTEERKTASG Lenti61 LLEPHNYIISLDVQFVDFDGVRFHLST-PDRK--TALLLSIRCWDELVRGVNDILKREYGSLLEGEYNVSLEIDLEQLRDAFFKSLAMLKRNALAAPFELGFLHYRD-EEVIYVQASSDRVTVIFSTMFR--EETDRVFG-KVFLQE-FVDARRQAAPQVLYTTREA-PLEIRDVGYVTFVLFPRHTITHIQLFRDYLHYHIKCSKAYMHSRMRHRVSEFQKVLNRAKTEDRKTASG Malgl1 LLGAENQIIAVDQMFTDFDGVSYHMES---SK-EGPLTLSIRCWPELAQGAMESLRQIYGTWIEPDYQITLSFDYGSVRETLIHAVSMLKRNAMAAPFERAFLHYRA-DESMYILPAHDRVTVVISTRFE--EEADRIFG-KVFLQE-FVDARRQNAPQVLYSNREP-PLEVRNTGYVTFVLFPRHTISHIQLFRDYLHYH---SMYRLHATV-----------------TRSTDAD Mellp23 LLEDQNIII---------DGVRYHLST-PNKK--TIILLSVRCWNQLVDGVLDIMKREYSQWIESDYDISLIFEIDQLRSSLIKSISLLKRNALAAPFERAFINYRP-EEAIYVIPNIDRVTVVFSTVFR--EDTDMVYG-KVFLQE-FVDARRQMAPQILYSNREP-PREISNMGYVTFVLFPRHTISRIQLFRDYLHYHIKASKAYIHSRMRARTNEFLKVLNRAKPEERKTASG Mnele LLEENNRVISVNIAAVDFDGVQYQISN-PDGD-KGVINLSMRMYEDLVAGVQDLLKREYGDSLEEGFDVTLRFELASLKEAMAKKASLLKRNCFASVFEKYFVHYHE-EEAVYISAQTDRVTVIFSTLFK--DPDDIVIG-KVFLQE-FKDARKQQAPQVLFSYGEP-PAELSNIGYVTFVLFPRHTINLIHQFRTYLHYHIKCSKAYLHSRMRSKTSEFLKVLNRAKPEEKKFGVG Monbr L---QNRIIPVEVTIADFDGALYHLSN-PEGD-RNKVQISVKFYHELQPGVNELMKREYGDMLESGYDVTIVVDLAAMPTVTIMKAASLRRNCFAALFEKFFLQFRD-QETLYINVLKDRVTVIFSTLFS--DADDVVIG-KVFMQA-FKDVRGPQAPQVLFSYLEP-PRELENVGYVTFVLFPRHTIDLLHTFRDYLHYHIKCSKAYLHQRMRARTSELLKVLNRARPDEKRTITG Morel2 ------------MSIVDFDGVSYHLATLDDND--AKLNLSWKCWHELVQGAVDVLKREYSRWIEHGYDFTLQFDLDNIPEDVIRRVSLLKRNAMAAPFERAFIHYRD-GEAIYVQNQQDRVTVIFSTLFK--EETDRVFA-KVFLQE-FVDARKQNAPQVIYSHREP-PLEIRSQGYITFVLFPRNTISRIQIFRDYLHYHIKCSKAYMHSRMRARVSDFLKVLNRAKPEEKKLASG Mucci2 LLDYHNVIIPVDMTVADFDGVTYHIST-PESK--SVLLISWACTHELFAGAQDVLKREYGDLLEQGYDVSLSIDLEQVRDELIKKVSLLKRNLLAAPLERAFVHYRE-EEAIYIKSNFDRITVIFSTTFK--DETDKIFG-KVFLQE-FVDARRQNAPQVLYSIREP-PMELRDISYVTFVLFPNHTISRIQIFRDYLHYHIKCSKAYMHTRMRARVRDFLKVLNRAKPEEKKTASG Mydma LLEINNNIVAIDIKVADFDGCIFHVGN-KDGD-KSKIIVSLKFYKQLQQGADELIKQIYGEFLEPGFDVTLLLDLDKLKEPLIKKIGLLKRNCFASVFERYFIHYRE-DETMYVEAKADRVTIIFSTVFK--DDDDVIIG-KVFMQE-FKEGRRQTAPQVLFSHKEP-PRELENIGYITFVLEKRHTINLIHTFRNYLHYHIKCSKAYLHSRMRAKTTDFIKVLNRARPEEKKTITG Neucr2 LLDYQNVLINIDQTVSDFDGVVFHIST-PESK--TKILVSIRCFQDLVRGAEQVLNREYADLVEAGYDFSIQVDLENLRDALVMKIALLKRNAMAAPFEQAYIHYRE-EEAIYVKASHDRVTVIFSTIFR--EETDRVFG-KVFIQE-FVDARRQNAPQVLFRN-DP-PLELQEIGYVTFVLFPRHVISHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPDEKKTASG Orpsp11 LLEVHNKIINVTEELADLDGVLYHLTS-SKKE--GYVVLSMNGYSQLVKGADEVLRREYGPYIEVGYDFSICLNQQDLRDALYKKFSLLKRNLLAAPFEKAFIPYRN-NESIYVFALQDHVTVIFSTEFK--EDTDKIFG-KVFLQ------------------------------------------------------------------------------------------- Pench1 LLDYQNALISIDQVVSDFDGVTFHLST-PESK--TKILISVKCYKELVQGAQEVLEREYGPYIEPGYDFSVQVDLENLRNDLIMKLALLKRNAMAAPFERAFIHYRE-EEAIYIKANWDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLFRN-DP-PLELAEVSYVTFVLFPRHNISHIQTFRDYFHYHIKASKAYIHTRMRKRTADFLQVLNRARPEERKTASG Phybl2 LLDYHNVIIALDMTIVDFDGVIYHLAT-PDSK--TVLHISWKCFNELVAGAQEVLKREYSEYLENGFDTTLVIDLEKVRTELIQKISLLKRNLLAAPFERAFVHYRE-EEAIYVKSNSDRVTVFFTTKFK--DETDKVFG-KVFLQE-FVDARRQNAPQVLYATREP-PMELRDMSYVTFVLFPRHTISRVQIFRDYLHYHIKCSKAYMHTRMRARVSDFLRVLNRAKPEEKRTASG Picst3 QIEQNNLLILLDRIITDFDFTTYHILTLPDHK--QLVLVSLKCWDDLNKGVVEYLNGKYAEYAEAGYNYSLVLDLAELKQKVIDELSFLKRHAMAAPFEKAFIKYRGSDESIYIKPSFDRVTVIFLTVFQ--DETDKIFG-RVFLQE-FVDARKQTAPQVLYSHKDA-PLDIQNKGYITFVLFPRHCISHIQFFRNYFHYHIKCSKAYMHSRMRFRVKEFLKILNRAKPENRKTASG Plicr1 LLEAHNVIISLDVQFVDYDGVRFHLST-PERK--TLLLLSIRCWDELVQGATDVLAREYGSLVEPEYNVSLEIDLEALRESLIKSVSLFKRNALAAPFERAFIHYRD-EEAIYVQASTDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSNRDP-PLEIRDVGYVTFVLFPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRHRVTEFQKVLNRAKTEDRKTASG Polpo LLETSNRILRIYNIFADFDGVKFHTHT-SEDK--QQLFVSFKGAADLLKGGQTYLKAVYGPLLEPGYDITLIIDVN-AKEELAHKVSQLKRNLMAAPFLMVFIDYRS-DESFYIKTQGDNVTVIFDIIFK--DSDDIVLS-KIFLQA-FVDVRKNNVPSVSFSQKDP-PLELKNHGFVSINLFPGHTADLIQTFRDYLHYHIKCAKGYMHTSMRNRVDGLLQVLNRAKPEVKRTFKG Pucgr2 LLEDHNKIISLDQAFVDFDGVRYHLST-PNKK--TIIMLSVRCWHELVEGVWDIMKREYADWIEPDYDISLVFEVEKLRSALIRSVALLKRNALAAPFERAFLNYRP-EEAIYVIPNVDRVTVVFSTIFR--EDTDMVYG-KVFLQE-FVDARRQTAPQILYSNREP-PREINNMGYVTFVLFPRHTISRIQLFRDYLHYHIKASKAYLHSRMRARTNEFLKILNRAKPEERKTASG Punst1 LLEPHNVIISLDVQFVDFDGVRFRLST-PDKK--SIILLSIRCWDELVQGALDILGREYGALLEPDYNVSLEIDLEQLREALIKSLSLLKRNALAAPFERAFIHYRD-EEAIYIQASHDRVTVIFSTVFR--EETDRIIG-KVFLQE-FVDARRQNAPQVLYSNRDP-PLEIRNVGYVTFVLFPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRYRVSEFQKVLNRAKTEERKTASG Rhior3 TANYHNVIIPIDMTVADFDGVTYHIST-PEVK--TILQISWGCAKELFEGAQDVLKREYGEYLEQGFDVTLAIDLEKVRDELIGKVSLLKRNLLAAPFERAFIHYRE-EEAIYVKSNFDRITVIFSTTFK--DETDKIFG-KVFLQE-FVDARRQNAPQVLYSIREP-PMELRDISYVTFVLFPSHTISRIQIFRDYLHYHIKCSKAYMHTRMRARVRDFLKVLNRAKPEEKKTASG Rhoto1 DLEPTNYYLTLDQSFVDFDSVRYHLST-P--VRKSLLLLSVPCWAELQAGAREVLEREYGQRLEEGYSVSLEIDLEQGRDALIHALTLLKRNALAAPFERAFVHYRP-EEAIYLIPSSDRVTVIFSTIFK--EETDRILG-KVFLQE-FVDARRQTAPQVLYSNREP-PLEIRRAGYVTFVLFPRHTITRIQLFRDYLHYHIACSKAYLHSRLRLRTSQFLKLLNRAKPEHQKTASG Rozal11 LLEYSNKVLSIDLRCADFDGVIYHVST-PNSK--SELVVSMKGFCQLEKGSQEFLQKEYQGFIETGYDLSLCFNLEK---NVSRDVSLLKSNCLAAPFDKAFIEYRD-REAFFIQSFHDRV----------------VHG-CYSWQSVFANARKQNTPQVLYS-KEP-PLELKNIGYVSFVLFPRHTIKLIQTFRDYLHYHIKCSKAYLHSRMRNKVNDFLKVLNRAKPEEKKTASG Sacce1 HLQPQNLLITMDRIVSDFDYTTYHISNTAEDK--SILLLSTKAWVSVSETLLKFLADHYSSLGEPGYDYTLQITLAELVQESILQLSVLKTIILSFPFELAIIKYRD-EENIFIKPSNDRVTIIFETIFQ--DETDKIFG-KVFLQE-FVDARKQSAPQVLYSH-EP-PLELKSRRFITFVLFPRHSICQLTLFRNYFHYHIKCSKAYMHSRMRFRVDSFIKVLNRAKVDARRTFTG Salro LLEVENRILPVDMTVADFDGTMYHVSN-PEGD-ATKVLVSVPFFHQLQQDVDSFMKGIYGDMVESGYDFSLLVDISKLPEVTISNVARLRRNCFAAVFTKFFLNYKE-KETMFINAMKDRVTVIFSTLFT--DKDDIVIG-KVFMKA-FQDVRGPSAPQVLFGHAKDVPRELENVGYVTFVLFPRHTIDLIHTFRDYLHYHIKCSKAYLHQRMRARTSSLLKVLNRARPDEKKTATG Schco3 LLEPHNTIISLDVQFVDFDGVRFHIST-PNTQQKTLLLLSISCWGELVQGALDILKREYGPLLEPEYNVSLLIDLEQVRAAFIESVALLKRNAMAGPFERAFIHYRD-EEAIYIQASPDRVTVIFSTIFK--DETDRVYG-KVFLQE-FVDARRQTAPQVLYTNREP-PLEIRDIGYVTFVLFPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRFRVAEFQKVLNRAKMEEKKTVTG Schpo1 SLDYNNIFISIDQVVTDFDGVTFHIST-PEEK--TKILISMKCYPELVNGTLDLLKQIYGAYVEMGYNFSILIDLQQLKEQLAMSISMLKRNVLAAPFHRAFIHYRD-EETIVLWPEHDRVTVVFSTKFR--EETDRIFG-KVFLQE-FVDARRQTAPQVLFSYRDP-PLEIRDFGFVTFVLFERHCISHIQVFRNTLHFHIKASKAYMHQRMRKRVADFQKVLNRAKPDERKTATG Sorma LLDYQNVLINIDQTVSDFDGVVFHIST-PESK--TKILVSIRCFKDLVRGAEQVLNREYGDLVEAGYDFSIQVDLENLRDALVMKIALLKRNAMAAPFEQAYIHYRE-EEAIYVKASHDRVTVIFSTIFR--EETDRVFG-KVFIQE-FVDARRQNAPQVLFRN-DP-PLELQEIGYVTFVLFPRHVISHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPDEKKTASG Sphar LLDDKNKILPVDVTLADFDSVLYHMSPVEGAK--SSLKISWPAFKEMQAGADDVLKRIYGDMIEKGYDFSIVVDSEALKDEVVSKVALLKRNVFAAPFERAFIQYRE-DSSIWLQARHDRVTVVFSTTFQ--DADDITLANKVFLQE-FVDAKKREAPQVIYSWKDP-PSELDNISYITFVLFPRHCINMLQMFRDYFHYHIKCSKAYLHTRMRARVSTSLKVLNRAKPEDKKTFSG Spipu1 DLQPSNRILKLQLKVADFDGVKYRLST-PESK--TVLNISMRCFGELQRGADAVLRREYGDMLESGFDVTVRVDLQNLKESLVRKLSLLKRNALAAPFEIAFIHYRD-EEAYYIKAQHDRVTVIFSTIFK--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSPREP-PMELRWVGYVTFVLFPRHCISRIELFRDYLHYHIKASKAYMHSRMRTRVDSFLKVLNRAKPEEKKTASG Sporo1 SLEPANRYLSLDQSFVDFDSVRYHLTT-PNTKAKNQLLLSVPCWSELETGARDVLEREYGTLLEDGYSVSLAIDLEQGRQALVTSISLLKRNALAAPFERAFIHYRP-EEAIYLIPSRDRVTCIFSTIFK--EETDRILG-RVFLQE-FVDARRQTAPQVLYSNREP-PLEIRKA-----VLFPRHTITQIQLFRDYLHYHIKCSKAYLHSRLRVRTNEFLKVLNRAKPDERKTASG Stehi1 LLESHNYIISVEVQFVDYDGVRFNLKT-LERK--TALLLSIRCWDELVQGAMDILQREYGSLLEPEYSVSLQIDLEQARENFIKSISLLKRNALAGPFERAFLHYRD-EEAIFVQAAKDRVTVIFSTVFR--EETDRIFG-KVFLQE-FVDARRQNAPQVLYSNRNP-PLEIQDIGYVTFVLFPRHTISHIQLFRDYLHYHIKCSKAYMHSRMRHRVAEFQKVLNRAKTEERKTASG Tapde11 DLGYENVLLPINQVISEFDGVTIHVTT-PDDKNPTQLLISMNCYDTLTKGAAEIMEREYPGMTEAGYDLSLALDLSSIQGTLIKKLSLLKRNALAAPFERAFIQYRE-EEAIFIQASSDRVTVIFSTVFR--EETDRVFA-KVFLQE-FYDARRQNAPQVLFSIRDP-PLEIRNIGYVTFVLFPRHCISHIQMFRNTLHFHIKASKAYMHQRMRARVQEFLKILNRAKPENKKTSTG Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LLESRNTVIRMDIQFVDYDNVRFHLST-ADSK--TVILLSIQCWPDLIKGAREHLQKEYAGLVEPEYDVTLSIDLEKLRSALVQKLALFKSTAMSAPFLAAFIKYRE-EEAMFIQARHDRVTVIFSTVFK--EETDRVYG-RVFLQE-FVDARRQSAPQVTYSNREP-PLEIRDWGYVTFVLFPRHTIHRIQLFRDYLHYHIKCSKAYMHSRMRARVAEFLKVLNRAKPEERKTASG Trire2 LLDYQNALIHIDQTVSDFDGVTFHIST-PEVK--TKILLSIRCFKDLAKGAEQVLQREYGQYVEVGYDFSVLVDLENLRDALAMQFALLKRHAMAAPFEQAYIHYRE-EEAIYVKASHDRVTVIFSTIFR--EETDRVYG-KVFIQE-FVDARRQNAPQVLFRN-DP-PLELQEIGYVTFVLFPRHVISHIQTFRDNFHYHIKASKAYIHSRMRKRTADFLQVLRRARPDERKTASG Umbra1 LLDYHNVILALDMTIVDFDGVLYHLST-PTSK--TNIQISWRCFPELINGANDILQREYGTMLQQGFDVTLNVDLTSLREELIRKVSLLKRNIMAAPFERAFVHYRE-DEAIYVKANQDRVTVIFSTRFK--DETDRVFG-KVFLQE-FVDARKQNAPPVLFSTREP-PLELREMSYITFVLFPRHTISRIQIFRDYLHYHIKCAKAYMHTRMRARVRDFLKVLNRAKPEEKKTATG Ustma22 LLGTENIIISVDQTFTDFDGVAYHLES-TSKA--GPLTLSIRCWSELVQGAMEVLKREYNSWIEPEYSVTLEFDYAKVRDALIASVSLLKRNAMAAPFERAFINYRD-DEAIYVIPSADRVTVVFTTTFK--EETDKVLG-KVFLQE-FVDARRQNAPQVLYSNREP-PLEVRDVGYVTFVLFPRHTISRIQLFRDYLHYHIKCSKAYMHSRMRHRVAEFLKVLNRAKPEERKTASG Walse1 LLEPENVIISLDQTFVDFDGVRYHMWT-PNSKSKNEIILSVACWSELEAGAFQVLQQHYGSDVEPGYDVSISVDLNTIRNQYINNLSLLKRNAMSAPFLQAFLHYRN-QEAIYIQAGIDRVTVIFSTVFQ--EETDKIFG-RVFLQE-FVDARKQTAPQVLYSTREP-PLEIRDVGYVTFVLFPRHTISRIQLFRNYLHYHIKCSKAYMHSRMRTRVADFLKILNRAKLDERKTITG Zygro1 HLQPQNILITLDRIISDFDYTTFHVSNSPEDK--SILLLSTKAWQSVQKGLLDYLQSKYQGCSEMGYDLTLQITLSQLTGESLVQLSLLKTIVLSYPFQLAFVQYRD-EESLFIKPASDRITVIFETSFQ--DETDKIFG-KVFLQE-FVDARKQSAPQVLFSH-EP-PLELQSKRFVTFVLFPRHSVAQLILFRNYFHYHIKCSKAYMHSRMRFRVDSFIKVLNRAKVDTRRTITG [Cluster1638.fasta_al_trimmed; alignment length = 346] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIRDRLSPVNDRSLHALALEDTHRAIMTYLWLRQR Ashgo11 LDISNPEWFPEAR-KLRRTIVVHLGPTNSGKTYHALEKLKKCDRGYYAGPLRLLAREIYDRFQKDNICNLLTGEEVISGTVEQYFDMVVLDEIQMLADEQRGWAWTNALLGVQASELHLCGEPSVLPFIQRLVA-MTGDKLVINEYQRLGKLEVESKPLERFHGLKKGDCLVSFSKRKTLDLKLQIE-RAKKCKVAVIYGSLPPETRVHQATMFNRGEADILVASDAIGMGLNLSIKRVIFTSAMKWNLTDSQTKQIAGRA--GRYKTLEMIQNSMKAPLWPPDRILAQILTKYPKITTLLEHFVMNLIELSLEDMNAPLRDLPFINFCYEELHHVLTLYMWLQIR Aspfu1 ADLRYPEWYPQAR-ALQRTIHLHVGPTNSGKTYHALQRLQASKNGFYAGPLRLLAQEVYHRFQASGICSLVTGDDVKSNTVEQPYDVGVIDEIQMLADPKRGWAWTRAVLGARAKELHLCGETRAVPLVRELAA-LTGDRLEIHRYKRLNPLKVMDQSIGDLKNLQKGDCLVAFSRVGIHALKADIE-KVTGRRAAIVYGSLPAEIRTQQAKLFNDNDYDFLVASDAIGMGLNLSIKRIIFETLVKRVLSVPEIKQIGGRA--GRYRDLPYIREAMETEIFPPDPVFQKFSAYFPPFEYLIKRLNAEIIDLPIEDQAAPMYTRDACAFALEGLHRSVILYSWLSYR Aurde31 ADMRYPELFPEPR-RIRRKIIMHVGPTNSGKTYNALRALAASKRGVYAGPLRLLAHEVYTRLNKGVICNMITGEEKRSCTVETHYDVAVVDEIQMIGDEQRGGAWTSAVLGLMADELHLCGEESAVPVVEALAK-ETGDELIVNHYERLSPLHAASSSLGDFSKLREGDCVVAFSRRLIFDLKHKIE-QSTSFRCAVAYGMLPPELRAEQAALFNDNEYGIMVASDAIGMGLNLKIKRIIFYTTQKWDLSLSTVKQIAGRA--GRFSDLPVIQLAMRIPIAPTPEQVQAILQLLPPPSVVFEILQAKLLEMSISEYHTPAPLKEVSRLVLERMHRVLIMYLWLSYR Batde5 SDLRTPELYPQAR-AMKRKIIMHIGPTNSGKTYAALERYKAVDSAIYCGPLRLLAQEVYQRMNAAGICNLLTGEERRSCTVEREFDVAVVDEIQLIGDQQRGWAWTHALLALQAKEVHLCGEGTTLDIVRKLCK-TTGDTLEINEYERLTSLTVAQKSLGNFNQIKPGDAIIAFSRKNVFNAKQFVE-LNTPYKAAIIYGGLPPESRADQAKLFNESDRQVLVASDAIGMGLNLNIRRIVFYTMQKFNLTVSQTKQIAGRA--GRFGDMALLHASMKMTITPTVEQVEQFSNSL-TYATLLDKFIAKLIQLNIRDRQSPCNPEEIVKFALEVKHRVTILYLWLR-- Botbo1 TDLRFPEWYPLAR-RVKRKIIMHVGPTNSGKTHRALQALAAAKVGVYAGPLRLLAHEVWERLNTGSICNLITGEEQRSCTVEVRFDVAVIDEIQMLADPERGSSWTQAVLGVCADEVHLCGEATSIPLVEKMVK-ETGDELVINRYERLTPLVCAKQSLNDLSRVRKGDCVVSFSRNGIFKLKRQIE-KVTGLRCAVAYGRLPPEVRSEQARLFNDSGYDVMVASDAIGMGLNLKIQRVIFETLDKWDLSLSQIKQIAGRA--GRFGDLSRLEEALASAISPTLALLTRLSQELINAAAVYETISTELVSFGLRDRGAPLPARDMAAFLLEYLHKSIVLYIWLSYR Botci1 ADFRYPEWYPATR-AMQRTFHLHVGPTNSGKTYHALQKLEAANSGIYAGPLRLLAHEVYTRFNAKGKCSLITGEERRSCTVESKVDVAVIDEIQMIGDEERGWAWTQAVLGVQAKEVHLCGEVRTTDLIKKLCA-MMGDKLIIHNYERLGKLQVMAKSLTPVSKLEKGDAVILFSRMRIHAMKNAIEAHHRGKRCAIVYGSLPPETRAQQAALFNDNDYDFLVASNAVGMGLNLSIKRVILESVKRHNLPISEIKQIAGRA--GRYKDHEILSSAMSKEIFPPANVIERFAEYFPPFSYVILRLIADIIQLTIRNRAAPVSLRDVKAFA------------CVSNN Caeel ----------------------------------------------------------------------------------------------MLRDEQRGWAWTRALLGAAADEIHLCGEPAAIDIVKKLLE-PIGETVEVRYYERKSPLAIADKAIESYSNIEPGDCIVCFSKRSIFFNSKKLE--ENGIKPAVIYGDLPPGTKLAQAAKFNDDECNVLVATDAIGMGLNLNIRRVIFNSC----LPTYAALQIAGRA--GRFGDLGTLKAILSEKIAPTYDQIETFSFHLPSFVRLLDLFLAVLIDLPLKVRTSPLNTEDFVKMALEQNYEILDQYMWLSMR Canalb1 VDFSNPEWFPEAR-KMKRKIIMHVGPTNSGKTYNSLIKLSKSKTGYYAGPLRLLAREIYEKFNSQGICNLITGEEVVSGTIEKKMDLCVIDEIQMIADPLRGSVWTNAVLGVLAHEIHLCGEESAVPFIQKMVE-ITGDELEIKKFNRLGKLTVEKSNT--LQQLKKGDCLVVFSKKKILKFKCDIE-RNTRLKVGVIYGALPPEIRSQEASKFNNGEYDVLVASDAIGMGLNLKINRIVFSGVNKFNLSVSQVKQIAGRA--GRFSSLVYIDQCLKTPIWPTSNIWRQYMANDPSLSSVYENFLLNLVAMIIDDQETPINFRTVIKFYLEDMHRLVLLFLWLSQR Cangl VDFSNPEWFPEAR-KIRRHIIMHVGPTNSGKTFRSLQKLKAADRGYYAGPLRLLAREVYEKFKHENVCNLLTGEEVISGTIEQNFDVVVLDEIQMMADLDRGWAWTNALLGAKAKEVHCCGEASTIPLIKKIVE-MTGDKLTINEYERMGKLVVEEEALKGYHSLKKGDCVVAFSKKAILDLKLEIE-KKTELKAAVIYGSLPPETRVKQANLFNSGEFDILIASDAIGMGLNLSIDRVVFTTSKKFDMTSSAIKQIGGRA--GRFKVLKAVREAINAPTWPTDEICTHVMTRFMTCKTLLETIAIEIIDITFSDKNAPLKDFPFKKFCYEALYNIIMLFFWLSNR Capow SDMRQPLTYHQAR-SMQRKFIFHAGPTNSGKTYSALKRFREANRGIYCAPLRLLALEVYDDTNNHGICDLVTGEDRKACTIEKVFDVAVIDEVQLIGDRDRGWAWTRALLGLAAHEIHVCGEPRALSIVESLLK-STGEDVQVHTYERLTPLVVAPHSIRNLANLRRGDAIIAFSRKELFRWKAEIE-RETRFRCAIVYGSLPPQTRAQQARLFNDSGFDILVATDAIGMGLNLNIGRIIFTTLQKFNLSPSEVRQIAGRA--GRFRDMGILIKQFNGPLMANFEQLEALSKQLPDMLDLFTKFAIKLLALSFKDRLAPANLENLLSFAFEQCHKMLDLYMWLSYR Catan2 ADLRHPEWYPGAR-LLRRQIIMHVGPTNSGKTHGALAELAAAPSGVYCGPLRLLAHEIHDRFTTRGICSLVTGEERRACTVEREYDVAVIDEIQVIGDAQRGWAWTQALLGLRAKRIYVCGEESAVPLVKRLLE-GTGDEVIVKRFERLTPLKVSPGVVNKLAGVQPGDCVVAFSRKEVFAYKYLLEKENPGLKCAVVYGALPPETRAEQARLFNESGYGVMVATDAVGMGLNLAINRVIFTTTRKYDLSISALKQIAGRA--GRYGDLRYIHETLPLTLQPTPDMIEAFAQQLPPLTGLLEKFLADRLKMAIRDQLAPVNTRSFVHIALEAVHRGILLYMWLANR Cioin SDISEPLWYENAR-SIKRKIVYHAGPTNSGKTHAALQRFYEAKTGVYCSPLRLLAREVCQKARDHGVCDMITGDDRDACTVERRYEIAIIDEIQMLSDMERGWAWTRAFLGVCAPEIHVCGEARAVDIVRQLAD-ECNDSFEVVTYKRLGKLRVKKHPVESFNNLKPGDCIICFNKSRIYSYQKKLN--SLGINSAIIYGSLPPRTKLEQAKKFNDHPCNVLITTDAIGMGLNLNIRRIIFSDLYKTTLTTSHALQIAGRA--GRFNHMPLLHKLLRQTLHPTFELLAEFANVLNSLSEVIVMFIAEYLEISLRDMSSPISSGNLAAFVLESLHEVLRLYMWLSYR CocheC53 ADLRYPEWYPATR-EIPRTVHMHVGPTNSGKTYHALKRLEEVKSGIYLGPLRLLAHEVYTRLDAKGKCALVTGEEQRSCTVETHFDVAVIDEIQMISHPERGWAWTQAFLGLQAREIHLCGEARTVPLMRELCA-LVGDKIHVHEYNRLTPLKVEPKSLGKLNNLQKGDCIVAFTVLGIHALRREIE-RKTGRKCAIVYGSLPPETRAQQARLFNDNEYDYLVASDAIGMGLNLAIKRVIFESTMKTDLQISDLKQIAGRA--GRYKDHKYLKSGMEKELFPPSQIVERFANYFPPFSYIMLRLIADAIHLSVQDRAAPINMRSLRRLTLEQLHKMIVCYLWLSYR Coere1 SDMRFPEWGVGAR-NMQRRIIMHVGPTNSGKTFHALQRLKAAKQGIYCSPLRLLAYEIYNRMTKMGICGLITGEDRRSCTIESAYDVAVIDEIQMLSDLHRGWAWTTALMGLRAKEIHLCGEPSAVPLVKRICE-SMDEEVEVREYTRLGKLKVSGVSLGDLGNVRKGDCVVVFSRKEIYEIKKAIE-EKTGMRCAVIYGGLPPESRAEQARLFNDSGYDVLVASDAVGMGINLSINRVVFMTLQKFDISVSQTRQIGGRA--GRFDDLQQLKKSMEQQIKPNLGMIEMFSHQFPSFAQLWCMFIARIIELSISDRYAPVSIRDLRQFALENWHRAITLYLWLSYH Conco1 FNFTSPDWFIPAR-RMKRKLIVHVGPTNSGKTYRALERLKTSQSGIYCGPLRLLALEVWKKFSDQGICNLVTGEERKSCTVETPIDVAVIDEIQMISDHQRGFAWTRALLGIPAKEIHLCGEPRAVPLIKWIGE-RLCEEVEVNIYDRLSPLSITQNP-PGVEGIKAGDCIVAFSRKNIFAYKNLIE-SQTKFKCAVVYGNLPPENRAIQASLFNSSGYDVLVASDAVGMGLNLNIQRMIFSKMTKFNISTSMVKQIAGRA--GRFGDFHILEEEMEKTIQPDASLIERATYLFPKLDQVLIMLIAKMLSLPVDVTFAPFKVRDAYRFALEQMHRIASLYIWL--- Conpu1 ADLSYPEWFPVAR-AMRRKVIMHVGPTNSGKTHNALRALAAARCGVYAGPLRLLAHEIWERLNKGQICNLRTGEEIRSCTVEAQPDVAVIDEIQMIADPERGPAWTHAVLGLPAKELHLCGEETAVPVVEAILR-DTGDELIVNRYERLSPLSVEESSLGDWGLVRKGDCVVTFSRTGIFNIKREIE-EATGLRCAVAYGKLPPEIRSEQAALFNNSEYDVMIGSDAIGMGLNLKIKRVVFETLRKFDLSLSQIKQIAGRA--GRYGDLPMLHKALATPLDVGGARLEALSHALPSMEAHLQVPIAEFLDLTLAEKYAPVAWQDLGEFCIETLHKVLVLYLWLGNR Copci TDRRYVEQFVETR-RMQRKVIMHVGPTNSGKTHHALRALAAAPYGVYAGPLRLLAHEIWERLNLGHITNMITGEEQKSCTVERTYDVAVVDEIQMITDPQRGSGWTNAVLGLAAKEVHLCGEETAVPIVEALLK-DTGDELIVKRYERLTPLKVEEESLGDYSKVQKGDCIVVFNRKGIFAVKKKVE-ALTGLRCAVVYGRLPPEIRSEQASLFNDSGYDVLIGSDAIGMGLNLKIRRVIFDSVKKFSLSISQVKQIAGRA--GRFGDLPYLREAVGSPITFDANTFSNLLSVLPSTSTVILAHTFNFIDLTARERNAPVTWRDVRTFLLESFHKSLVLYIWMSFR Croqu1 IDMRRPDRYPDAR-RYKRQIHLHVGPTNSGKTHSALRALHGANTGVYAGPLRLLAHEVFTRLNEGQICNLITGEEQRSCTVEQYYDVVVIDEIQMIGDVYRGDAWTQAVLGTQAKELHLCGEESVVELIRQLAQ-YSGDEFLLHRYQRLTPLKVSDESLGDLSKVQKGDCVVTFSRSNIYAIKKYIQ-QKTGLRVGMAYGGLPPEVREREARMFNEGGYDVLVGSDAIGMGLNLKIKRVIFEALYKFDLSTSQIKQIGGRA--GRYGEMPLLRECMSAPIKAPFETVEGLARLVPRFSTLLGLRIADSLELSLSERSAPANSRNLRAWALESLHKCLVLYLWLGFR CryneH991 TDLTRLTDFLPSR-AIKRHFHLHIGPTNSGKTYNALKALSIATTGAYAGPLRLLAHEVWERMNLGSVCNLLTGEERRSCTVETGFDVVVIDEIQMLGDGQRGGAWTKAVLGVAAKEIHLCGDETTVDLLRGMIA-FLGDDLTVHQYNRLTPLSVANESLNDYTKVEDGDCIVTFSRSNIFEVKKQVE-SQAGKKCAVVYGALPPETRAEQARDFNDGASKVLVASDAVGMGLNLKIRRIIFESLSKFNLSLMQIKQIAGRA--GRFKDLPILKELMTWSLEIPTSGLVQLSTLLPTYAELLSHFLAELVELSLGEMFAPVNTRDFVNLILETLHKTLVLYIWLSFR Crypa2 ADFRFPEWFPATR-TMQRKIHLHVGPTNSGKTYNALKALEESKTGIYAGPLRLLAHETYMRFMAKGKCALVTGEELRSCTVERRVDVAVIDEIQMIGDEQRGWAWTQALLGVQAKEVHLCGEERVVPLIEAICA-KMGDEVVVHRYQRLNPLQPMQEGLGKFENLRKGDAVVSFSRVNLHTLKAGIE-EATGKKCAIVYGALPPESRAQQAALFNDNDYDFLAASDAIGMGLNLEIRRVVFEAVTKHDLTLPELKQIGGRA--GRFRDLDVVHESFDQELFPPSFVIEKFASYFPPFSFILLRLIATLIQLTVHDRTAPVSLKDVRALALESLHKSLTLYLWLSYR Debha1 VDLSNPEWFPEAR-KMKRKFIMHVGPTNSGKTYNSLRKLAKAKSGYYAGPLRLLAREIYERFHDQGICNLITGEEVISGTIEKKMDICIIDEIQMIADPRRGEAWTNAVLGVQAKEIHMCGEESAVPLILKLAK-ITGDEVEINKYNRLGKLTVSDKEV-NFKNLQKGDCVIAFSKRKILELKCEIE-RSTNLKVGVIYGALPPEIRSKEANGFNSGQYDVLVASDAVGMGLNLKIKRIVFFATKKFNLTASETKQIAGRA--GRFSDLIFLKKMMNEPTWPTDKVWTYYMSKFPSFYDILAQFILNLFLTTIEDQLAPVNINMAFKFFLEENHKLVLIFLWLSQR Dekbr2 MDVDNPEWFPNAR-KLKRKFIMHVGPTNSGKTYHALKRLETCTKGYYAGPLRLLAREVYDKFQKKNICNLVTGEEVLSGTIEESYDVVVVDEIQMIGDQYRGSAWTNAVLGVRAKEIHLCGEISAVPIIKRLVA-MTGDDLEIKTYKRLGKLVVDDSIV--MTDLSKGDCIVCFSKTAILDMKIQIE-RQTNFKCAVIYGALPPETRSQEAQRFNDGIYDIVVASDAIGMGLNLKINRVIFTTTQKFNLTSSNIKQIGGRA--GRYGELENVSKGVEGDLWPPDDLWIKYYSMFANLVTIYRRFMSGFFKFLIQDQTNPNQPMKLKEFMLEQFHKMLSSYMWLAYR Dicdi SDLREPKWYTEAR-KFKRNIILHVGPTNSGKTYNALKRLMESESGVYCGPLRLLAHEVYDKMNENGLTSLMTGQLRISCTIEKMVEVAVIDEFQLMSDTIRGQSWTRAILGIPAVELHLCGDNTAIELVKKICE-ITGDTLTINNYERLSTLVIDEEPIASMGDIKKGDCLICFKKKDIIFYKNYLE--KQGLKCAVVYGSLPPTTRVQQAKLFNDESVDVLIATDAIGMGLNLNIGRVIFLTLKKYDLYASEVKQIAGRA--GRFGDLAKIRKDWQSPISPLSQQIEKF-SLLPKFSEVLTEFIAQITDMSVKDKQCPLSNSKYIKYALESYYSVTDIYLWLSNY Dmel SDLRQPNWYSNAR-AITRKIVFHAGPTNSGKTYHAMERYLSAKTGVYCGPLKLLATEVYNKANERGTCDLVTGEERKACTVETPYEVAVIDEIQQIRDPQRGWAWTRAFLGLIADEVHVCGEPGALDLLQKICE-TTGETVEVRLYDRLTELTVENTALGSLDNIVPGDCIVCFSKHDIYTVSREIE--ARGKEVAVIYGGLPPGTKLAQAAKFNANSCKVMVATDAIGMGLNLSIRRIIFYSLIKPSISVSSALQIAGRA--GRFRDLQTLQRILARTLHPTADQIELYAYHLPSLSNLMDIFLAEMIQLPLRARCAPINRKMFLKVALEAVFDVMDLYLWLSYR Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba SDMRMPAFYPQAR-SMKRKIIYHAGPTNSGKTFRAIQALRKSESGIFCGPLRLLALEVFDKLNQAGVTSLLTGQEQKSCTVESPVEVAVIDEIQLLADAQRGWAWTQAVLSAPAKEIHVCGDATAIDILQRITA-LTGDEFEVHEYHRRSQLAVEKSAFTDFTKLERGDCVIAFSRRELHSLKTRIESETSHK-CCIIYGRLPPETRAMQARLFNNSPYTILLASDAVGMGLNLNIRRIIFSTLLKFDLSTSHIKQIAGRA--GRSSDLPVIKKALKTELTPVDEQIINVASIYPPLSSLVSLLLADVIQLTLEERRAPISASSLKRFALEEFYSIADLYLWLNQR Fomme1 VDHTHPEWYPTAR-MLRRKIHMHVGPTNSGKTHNALRALAASRRGVYASPLRLLAYEIFDRLNNGRICNLVTGEEVRSCTVEKRYEVAVVDEIQMLSDPERGGAWTAAVLGLHAEEIHLCGEAGAVPLVQEMLK-DVGDELIVHRYERLTPLTVASKSLGDLTKIQKGDCVVSFSRSMLFSLKEQIE-EATGMRCAIIYGRLPPEVRSEQAERFNDSGYDVLVGSDAIGMGLNLKIKRIVFESSQKWDLSLSQLKQIAGRA--GRFGDLPTVRKAVESRLPTTQNMFHSLEQLVRKFSAVFDILVVPVIDFTLEERLAPVIWRDAKRFILESLYRVVVVYMWFSLR Fusgr1 LDFRFPEWFPATR-AMQRKIHVHVGPTNSGKTYRALKALEASKRGVYAGPLRLLANEVYQRLTAKGLCALLTGEEVRSCTVEEQFDVAVIDEIQMIADEDRGQGWATALLGVQAKEVHLCGEERTVKLIESICA-SIGDECIVHRYERLSPLEPMDNALGDYGKLEKGDAVVAFSRMNLHALKLTIE-KKTGRRCAIIYGSLPPEVRVQQAALFNDNDYDFIVASDAIGMGLNLEIRRVVLETCAKYDLSYPELKQIGGRA--GRYKDLKVVHKAFEADVTPPASVVERFSTYFPPLSFILMRIIADMIQLTIYDRNLPIAARALRALALESLHQAINQYIWLSYR Galma1 TSRLYPDGFPKAR-AMHRKIILHVGPTNSGKTYHALRALAAAKTGVYAGPLRLLAHEIWDRLNTGQICNMITGEERKSCTIETQYEVAVIDEIQMIGNRSRGGGWMNAVLGVCAKEVHLCGEETAVPIVKALLR-HTGDEVVVKRYERLTPLVVEKESLGDFSNVRVGDCIVAFSRNRIFELKRRVE-AKTGMRCAVVYGRLPPEIRSEQATLFNASGYDVMIGSDAIGMGLNLKIKRVIFEALRKFELSSSSIKQIAGRA--GRFGDLADLANGLAKPIGYSSDLLTSTLSILPSMMVALSAPVTSFIDMDNEDKYAPVPWSDVAKMLLEAFHKILVFYKWMSFR Ganpr1 ---------------MQRRIILHVGPTNSGKTYAALSHLKSSTNGAYLGPLRLLAHEVAVRLNRDGKTSLLTGEERQACTVERKYDTVVIDEIQMLADQSRGWAWTNALLGIQAKEIHLCGEPSGIDLVQNLAE-ECGEVVEVVEYKRLSPLEVA-PSLGDYKQIKKGDCVVTFSRLDVFRRKREIE-KATGLQCAVVYGSLPPEIRQLQSRLFNKSSCDVLVATDAVGMGLNLNIQRIIFDRLDKFDLSPSLVKQIAGRA--GRFEDWKYLEECMNSDIQPSLEQITKFAVHLGKLSGLLSSFLANLIDMTLQEKLAPV-------------------------- Gloin1 SDLSFPEWHPSAR-AMQRKIILHVGPTNSGKTYNALQKLEKAESGIYCGPLRLLAHEIFDRMNNKSICNLVTGEERRASTIETPLDVAVIDEIQMISDQQRGWAWTQALLGLQAKEIHLCGEASAVKLVKSICA-SLNEDVEVREYNRLSKLVVANESLGDIKKIQKGDCVVTFSRKAIFGLKHEIE-TATGLRCAVVYGALPPETRAMQAKLFNNSGYDVLVASDAVGMGLNLNIRRIVFETVRKYDVPIPQIKQIAGRA--GRYGDLRYVQKAMVTPLQPTMEMVEQFAHQLPQFEKLLEKFIAKSIELTIPERTSPVNISDIKMFAIELKHRIIMLYLWLSYR Hisca1 ADLRNPEWYPAAR-SLHRTIHLHVGPTNSGKTYRALKRLETAKTGFYAGPLRLLAHEIYTRLNAKGICGLVTGDEVRSNTVEQDVEVGVIDEIQMIADPHRGWAWTRALLGARAHELHLCGEERVVPLIRDLAG-LMGDKLEIHHYERLNPLKAMNRSLGNLSNLQKGDCVVAFSRIGIHGLKQDIE-KATGRRAAIVYGSLPAEIRSQQADLFNNNDYDFLVASDAIGMGLNLSCKRIIFESVVRKLLSVSQVKQIGGRA--GRYR-------------------------------------AAEAIDLSMDDKSAPTHMRDFKEFVLETLHRSLVLYLWLSYR Klula1 LDISNPEWFPEAR-KLKRTIIMHVGPTNSGKTYNALQKLKNCPRGYYAGPLRLLAREVYDRFQNEGICNLLTGEEVISGTVERDFDICVLDEVQMLSEKDRGWAWTNAILGVRAKEIHLCGEESVLPLMDKIVK-LTGDTLVVNRYERLGKLEVEHQPLNGLKGLKSGDCVIAFSKKSILDLKLRIE-KETNLKVAVVYGSLPPETRVKQAKLFNSGEYDILVASDAIGMGLNLSINRVVFTASYKFNLTFSNIKQIGGRA--GRFKILRDVRKGINAPVWPTDELVNDLLSYYPKLTVLLNKFVVSTFELTLKDKNAPVRINPFKKFCYEEFHQLINLYCWLHIR Lacbi2 ----------------------------------------------------------------------------------------------MIADPQRGSGWTSAVLGIIAEELHLCGEETAVPVVQALLK-DTGDEVVIRRYERLTP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ADLSRVWQYTPARMSPPRKFIMHVGPTNSGKTHNALRALAAAERGIYAGPLRLLAHEIYDRLNKGQICNMVTGEEQKSCTVETYWDVAVIDEIQLIADKQRGGAWTGAVLGLNAREIHLCGEESAIPLIEAIVR-DLGDTLEVHHYKRLTPLVVAEKSLGDLGKVQAGDCVVAFSRSGLFGLKHSIE-KATKMRCALAYGRLPPEIRSEQAALFNRSDYRVLVGSDAVGMGLNLKIKRVVFESVAKWDLSASQIKQIAGRA--GRFGDLQVVRKALAASLNMTMETVTPVVHALPKGSTIGEVFAMKTIDLTLEHRNSPCPWRDARSLLLETVHKVLDLYLWFSYR Malgl1 TDLRAPLTYSSAR-SLTRQIHLHVGPTNSGKTHGALVTLSKARTGLYAGPLRLLAHEVWERMNQGTICNLRTGEEVRSCTVERAYEVAVIDEIQMIADIQRGFAWTQAVLGLPAKELHLCGEASAVPLIQRLVE-MCGDELHIHNYNRLSPLHVASSSLGDLTKVEPGDCVVAFSRSTIFWLKEQIE-ARTGLQCAVAYGALPPEIKSEQAKLFNSGKLDVMVASDAIGMGLNLRIRRVIFDTLSKWNLSLSQIKQIAGRA--GRYGEMEYLRAALAAPIQPSTRKLESLALLLPSVSTLLEEFMSTIIELTHAEKNTPVNMRDVGNAILESLHRTLTLYLWLGFR Mellp23 IDMRRPDKYPDAR-RYKRQIHLHVGPTNSGKTHSALRALHGAHTGVYAGPLRLLAHEVFTRMNKGQICNLVTGEEQRSCTVEQYYDVVVIDEIQMIGDIYRGDAWTQAVLGTQAKELHLCGEESVIELIRKLSI-DCGDEFILHEYQRLTPLKVSEQSLGDLSQIQKGDCVVTFSRNNIYAIKKLIE-EQTDLRVGMAYGGLPPEVREREARMFNEGGYDVLVGSDAIGMGLNLKIKRVIFEALYKFDLSTSQIKQIGGRA--GRFGEMPLLRKCMVAPIKAPFETVQGLARMVPRFSTLLNLRIADLLELSLAERSAPASSRNLRSWALESLHKCLVLYLWLGFR Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -----PLTYPEAR-KCRRRIIIHRGPTNSGKTYGAMQAAAAAKTAMFCAPLRLLAWEQYERLRNGHQAELLTGQE--ACTVERHYDVAVIDECQNIGSAERGWAWTNAILGARADVLYLIEDGSATQLLQNIAK-VCGDDVEVIDHQRLAPLHVQREPLINFSHLREGDCLIGFNRRELFNLKAQAE-AATGLKCAVVYGALPPDVRKAQATLFNHSDYKLLAASDAIGMGLNFDIGRVIFSTVWKFDLRPTELRQIAGRA--GRYGDT------------------EVLQRAL---------------------------------------------------- Morel2 SDLRYPEWNPAAR-LMKRKIIMHVGPTNSGKTYNALQRLQAAESGAYLSPLRLLAHEVFERMNDAGTCNLITGEERRSCTVERKIEVAVVDEIQMLADPDRGWAWTHALLSLPAKEIHLCGEPTVVDLVKKICA-LTNEEVEVHRYDRLSKMEVMDESLGQLDKIQKGDCVVTFSRKNIFLLKRHIE-ASTGLRCAVAYGSLPPESRSTQAKLFNNSGYDILVASDAIGMGLNLNIRRIIFEATEKFDLSLTQLKQIGGRA--GRFGDIPTLKRAMAAPIQPTADMLQQFSIQMPPFSYVLKTFAAEILDMPVRERSAPIQVRDAVKMALESSHRIIMLYLWLR-- Mucci2 ---------------MKRKIILHVGPTNSGKTYRALKRLEQAESGIYCGPLRLLAHEIFEKMNEKGVCNLLTGEERRSSTVEKTMDVAVIDEIQMIADPDRGWAWTQALLGLQAKEIHLCGEASAVPLVKKICE-TLDEEVVVNNYERLTPFTVSFETLNDLSKVTKGDCIVAFSRRDIFNLKEKIE-KATGLRCAVAYGALPPETRALQAKAFNESGFDVLVASDAVGMGLNLNIRRIIFSTIYKFDISIPQLKQIAGRA--GRFNDIFYVRQAVSAPLQPTVDILELFALQLPKFSGLLQKFIADKLELPLKDRTAPVNIRTIERLALESSHRNIMLYMWLR-- Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ADLRFPEWFPATR-QLQRTIHLHVGPTNSGKTYNALKALENAKSGIYAGPLRLLAHEIYTRFTAKGKCALITGEEQRSCTVEWKVDVAVIDEIQMIADEHRGWAWTQAVLGCQAKELHLCGEERVVDLIQELCA-RLGDKCIVHRYQRLNPLLPMEQAVTDFKNLQKGDAVISFSRVNLHSLKAGIE-EATGRKCAIVYGSLPPETRAAQAALFNNNEYDFLVASDAIGMGLNLEIKRVVFESAFKFDLTIPEVKQIGGRA--GRYRDLGVIRKHLQNDILPPSHIIERFASLFSPLAFVLSRLISDVLKLSIYDRTAPVSLRELRAFALEGLHKAVTLYLWLSYR Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ADLRWPEWYPRAR-SMQRTIHLHVGPTNSGKTYHALQRLAKSKNGFYAGPLRLLAQEVYHRFKADGVCSLVTGDDVKSNTVEQEYDVGVIDEIQMIANSSRGWAWTRAFLGAQATELHLCGETRAIPLIRELCA-LTGDKLEVHRYERLNALEVMPRSLGNLNSLEKGDCVVVFSRKGIHAMKADIE-KTTGRRAAIVYGGLPAEIRTQQANLFNDNDYDFLVASDAIGMGLNLSCKRVIFDTLVKRVLTVPEIKQIGGRA--GRYRDLPYIQQAMKLEIFPPESVFRKFAAYFPPFEYLIKRVNAEIIDLPFEDQVSPMDRKSTGAMALESLHRAVILYLWLSFR Phybl2 SDLRFPEWFPEAR-QMQRKIILHVGPTNSGKTYNALKRLEGAESGIYCGPLRLLANEIYEKMNDKGVCNLLTGEERRSSTVEKPIEVAVIDEIQMIGDPQRGWAWTQALLGLKAQEIHLCGEASVVPLVKEICA-SLNEEVIVNEYKRLTPVTILDETVPQYTDVKAGDCVIAFSRTSIFNIKERIQ-ESTGLKCAVVYGGLPPETRALQAKAFNESDIDVMVASDAVGMGLNLNIKRVVFSTIAKFNISIPQLKQIAGRA--GRFGDLSYVKECMDTGLQPTVDILEMFALQMPRFSGLLQKFISDTIELPLRDRTAPVNVRNIEDLALETAHKTIMLYMWLSIR Picst3 IDLSNPQWFPEAR-KMKRKIVMHVGPTNSGKTYNSLKKLAEAKTGYYAGPLRLLAREIYEKFLLTNVCNLITGEEIISGTIEKKMDVCVIDEIQMIADPGRGSIWTNALLGVLAKEIHLCGEESAVPLIKKLAK-MTGDEVEVKQYKRLGELKVTDKAI--YNKLEKGDCLVAFSKHKILQLKCEIE-RRTNLSVGVVYGALPPEIRSEQSRKFNSGEFDILVASDAVGMGLNLKIKRIIFQTVRKFDLTVSSVKQIAGRA--GRYSDLMYIKQAMNAPIWPTFDIWKQYMAKFSSLYDSLLQFLMKLFLVPIDDQLCPINLNMTFKYILEDHHKVVLMFLWLSQR Plicr1 ---------------MKRKIIMHVGPTNSGKTHMALRALAAAESGVYAGPLRLLAHEIWERLNFGQICNMLTGEETKSCTVETMFDVAVVDEVQLLADPERGFAWTQAILGLSAKEIHLCGEEAAVPLVQAMME-ETGDEVIVNRYQRLTPLTVQDQSLGQLSQVRKGDCIVTFSRSGIFRLKKKVE-ELTGLRCAVAYGRLPPEIRSEQAALFNDSGYDVMIGSDAIGMGLNLKIKRVVFDSVHKWNISNAQIKQIAGRA--GRYGDLPILRAALAEPVGFDS--LEKLFDFLDRTQLLLDAQRSRFIDLLPRERQAPIPWQDVAKLMLELLHKTIVLYMWLGQR Polpo ADLKYPRWFPEAR-AIKRKFVLHVGPTNSGKTHNALEALKSADSGVYCGPLRLLAQEIYDRLNAVDVCNLLTGQQNLACTIERLVDVAVIDEFQMIADLGRGWAWTRAVLGLPAREIHLCGDNTAVSLIEKLAK-TTGDTIEVRYYERLAPLRVESKSV-----LEKGDCIISFSRRDILETKSLIE--RRGLKCAVVYGALPPETRANQAQLFNDSGYDVLVASDAIGMGLNLNIRRVIFSEIKKFDLVHSEVKQIAGRA--GRFRNIGYIKEQLELPIFPQEAQLEQFARHLGTFSELLERFVARLIDLPVKTKMAPLKLKEEKIYVLEECYAILDLYLWLAQR Pucgr2 IDIRRPDLYPDAR-RYKRQIHLHVGPTNSGKTHSALRALHSAHTGVYAGPLRLLAHEVFTRINAGQICNLLTGEEQRSCTVEQFYDVVVIDEIQMIGDHFRGDAWTQAVLGVQAKELHLCGEESVVGLIESLAN-SCQDEFILHRYQRLTPLKVADSSLGDLSKVQRGDCLVTFSRNNIYALKKAIQ-SATDLRVGMAYGGLPPEVREREAQMFNEGGYDVLVGSDAIGMGLNLKIKRVIFQSLHKFDLSTSQIKQIGGRA--GRFGDMSLLRRSMAAPLKAPFTTVEGLARRAP--------GVPD---------PHPARIRD---------------------- Punst1 TDLSYPERFPNAR-SMRRKIIMHVGPTNSGKTHNALRALAAARTGVYAGPLRLLAHEIWERLNKGQICNLVTGEEQRSCTVEQMYDVGVVDEIQLIKDDDRGGAWTSAVLSLCAKELHLCGDETAVPIIEDIVK-DTGDELIINRYQRLTPLHVAPKSLSNFKNVKKGDCVVTFSRNNIFQVKEQIE-EETGLRCAVAYGRLPPELRSKQAALFNKSGYDVIVGSDAIGLGLNLKINRVVFEAMHKWDLPTPLIKQIAGRA--GRYGDMPILRAAMEAPLHINAAEADPVFQALPTTSAAFEALRTEFVDLTLAERNAPFQLRGAEEVVLEQLHKTLAVHVWYGYR Rhior3 ----------------------------------------------------------------------------------RPLDVAVIDEIQLIADPNRGWAWTQALLGLKAKEIHLCGEEAAVPLIRKICE-DLDEEVVVNKYGRLTPYTVSDMPLSDLSQIEKGDCVVAFSRMNIFDLKKRIE-AQTGLKCAVAYGSLPPETRALQAKSFNDSGIDVLVASDAVGMGLNLNIKRVVFSNIKKFDISIPQLKQIAGRA--GRFGDLRYIKEAVAAP---------------PTFSGLL---IADNLELPLRDRTAPVSTRSIKILALEESHKQIMLYMWLSTR Rhoto1 ADRRFAEQYFSAR-QRRRKLILHVGPTNSGKTYNALVALARARTGAYAGPLRLLAHEVFTRFNEGKICNLVTGEEKRSCTVEKRLEVGVIDEIQMIGDPQRGAAWTAAVIGSTCDELHLCGEESVVELIQTIAA-ELGDECIVKRYQRLSPLVVAEKSLGDLSKIRRGDCLVTFSRSNIFAFKRAVE-QRTGLKVAVAYGGLPPEVREEQARAFNAGEFDVLVASDAVGMGLNLKIRRIVFESVHKFDLPTPQVKQIAGRA--GRYGDLPILREAMKEPITAPPEAYKELYSILPPLSRVVSLSNTDTIALTFEERLAPVNKRDLTDFALESNHRCLTLYLWLSYR Rozal11 ------DW------SQQR---------------------------LYGG---------------------------------FDYDY-LVDTIN--------------------------------------------------------------------------DC------------KNNIS--ETSLKATIA----P----------FD--------------------------------------------------------------------------------SYYSLLNNFILSLIELSISDRAAPLYSADLKLYAYENVYQILRLYCWFSEK Sacce1 VDITNPEWFPEAR-KIRRHIIMHIGPTNSGKTYRALQKLKSVDRGYYAGPLRLLAREVYDRFHAEKICNLLTGEEVISGTVEQKFDVVVLDEIQMMSDGDRGWAWTNALLGVVSKEVHLCGEKSVLPLVKSIVK-MTGDKLTINEYERLGKLSVEEKPIDGIKGLRKGDCVVAFSKKKILDLKLKIE-KDTNLKVAVIYGSLPPETRVQQAALFNNGEYDIMVASDAIGMGLNLSIDRVVFTTNMKYNMTSSQIKQIGGRA--GRFKVLKSVRKAIEAPTWPTDEICAQLMTQFPPTSVLLQTIVIGLFEIPFFDKNAPVKDMPFTKFCYESLYNIITLYFWLSNR Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 TRRPFIEEFPHAR-HLKRKIIMHVGPTNSGKTHNALRALAAAKLGIYAGPLRLLAYEIWERLNLGQICNMVTGEEHKSVTIESSYDVAVVDEIQMIADDQRGCAWTNAVLGLAAKELHLCGEDTAIPLVQELIA-QTGDELVINRYERLTPLEVEKESLGDFSKIRKGDCVVCFSRQKIFQVKEEIE-KATGLRCAVVYGGLPPEVRSEQATLFNDSGYDVLVGSDAIGMGLNLKIGRVVFSTCQKHDLSLSQTKQIAGRA--GRYGDMEHVRQALAAELNARNELYSAVRAALPKFDLWLDALMADVIDMRLVDIAAPIGWRDARRLLLERLHKILSAYVWLGLR Schpo1 TDLKNPEWYPGAR-KLRRHIIMHVGPTNSGKTHRALERLKTCKKGIFAGPLRLLAHEIYNRLQANGICNLYTGEEIRSCTVETTFDVAVIDEIQMMADPSRGYAWTQCLLGLQAKEIHLCGEESVVKLVRSIAK-MTQDDFTVYRYERLNPLHVAEKSLGKLSELKDGDCVVAFSRKNIFTLKSKID-QALGKKSAVIYGSLPPEVRNQQASLFNSSDENILLASDAIGMGLNLGVKRIVFSDLKKFSIPVPQIKQIAGRA--GRHNDFAKLNRAMNLPIGAKDDLFFRYLSLFSPQKLIFDRYIIEYLDLTIKDKGCPVLKHSIREIGLEQLHKLIVAYMWASIR Sorma ADLRFPEWFPATR-QLQRTIHLHVGPTNSGKTYNALKALENAKSGIYAGPLRLLAHEIFTRFIAKGKCALITGEEQRSCTVEWKVDVAVIDEIQMIADEHRGWAWTQAVLGCQAKELHLCGEERVVDLIQELCA-RLGDKCIVHRYQRLNPLLPMEEAVTDFKNLQKGDAVISFSRVNLHALKAGIE-GATGRKCAIVYGSLPPETRAAQAALFNNNEYDFLVASDAIGMGLNLEIKRVVFESAFKFDLTIPEVKQIGGRA--GRYRDLEHIKKHLLKDIMPPSHIIERFASLFPPLAFVLSRLISNVLKLSIYDRTAPVSLRELRAFALEGLHKAVTLYLWLSYR Sphar -----------------------------------------------------------------------------------NVEIAVIDEIQMIADEDRGWWWVRAVLGVPAKEVHCCGDHTALSLLKRLTD-ITGDNLIVHEYTRLSELE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 SDLTSPDWHSGAR-SMKRKIIMHVGPTNSGKTYAALQRLEQCATGIYCGPLRLLAHEVYERLNSKGVCNLLTGEERRAATVEKRFNVAVLDEIQMIGDRTRGWAWTQALLGLQAEEIHVCGEPTAVPLVQAMAK-ETGDHVQINTYQRLTGLTVKGAGLGKLADLKRGDCVVTFSRQNIFALKRQIE-EKTRLRAAVIYGSLPPETRAEQAKLFNNSVYDVLVASDAIGMGLNLNIGRMIFERVEKWDLTVSEIKQIAGRA--GRFGDMHTLRRAMKVKLHPTLEQIESFSKYL-SLASLLDRFIANTIALTLRDRLAPCNIKDMLTFALEAQHRVIILYMWLSQR Sporo1 ADNRFAETYPSAR-QHRRKLILHVGPTNSGKTYSALVALARARTGAYAGPLRLLAHEVFSRFNQGKICNLVTGEEQRSCTVERRLDVGVVDEIQMIGDPQRGSAWTQAVVGSLCDELHLCGEESVVELVKGIAE-EMGDECVVKRYERLSPLVVADYSLGDLKKIRRGDCLVTFSRSNIFMFKRAIE-SKTGLRVAVAYGGLPPEVREEQARAFNAGEYDVLVASDAVGMGLNLKIRRIVFESLHKWDLPTPQIKQIAGRA--GRYGDLPLLRAAMKEPSTPPFESFKHIYELLPPMSRIFSLAVGDKIALTFQERSAPVNLRDXSRFCLESFHRSLTLYLWLSYR Stehi1 VDFTTVDSFPEAR-VMRRKIIMHVGPTNSGKTYRALRALAAAPVGAYAGPLRLLAHEIYERLNTGQICSMITGEDVKACTIEKRYDVVVIDEIQMITDSERGHSWTAAVLGTAASELHLCGEDTAVPIIEALAK-MTGDELIVNRYERLSPLEVAEKSLGDLTKVTKGDCIVTFSRSKIFQLKDAVE-KKTGLKCAVAYGRLPPEMRNEQARQFNDSEIGVLIGSDAIGMGLNLKIRRVIISSMAKFDLSTSQTKQIAGRA--GRFGDLPLLREAINAPVGWLVGVFEGVMAALPTLSTAREALLVEFVDLPISERLCPFPFQDLGSIYLESLHKVLVAYSWLHMH Tapde11 ADMTRPEWYPVAR-SVPRKLHLHVGPTNSGKTYHALQRLQKAQSGCFAGPLRLLAFEIWDRFNKANVCNLLTGEERRSSTIEEEIDVLVIDEIQMIADPERGPAWTQALLGCPAREIHMCGEASVVELVQKIAA-TLGETVEVHEYTRLGALQPLTESLGTFKDIQEGDAVVTFSRQNIFDVKKSIE-QTTGKKCAVVYGGLPPETRASQAKLFNDSGYDVMVASDAIGMGLNLSIKRVIFESVEKWNVPVPQVKQIAGRA--GRFKDIQYLHESLATPLRPPLELVEAFSRPYPRISMVMQQLVFDLLHLSFGDRDAPLKNRDYLEMAIESLHHQLTMYLWLSLR Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 TDISHLGEYISAR-SMSRHFHLHIGPTNSGKTYSALKALSRAGTGAYAGPLRLLAHEVWERLNLGTVCNLVTGEERRSCTVESPYDVVVVDEIQMMGDPQRGSAWTNVVMKLRAHEIHLCGDETTVGLLKRMVASFGGDQLTVHRYDRLTPLTVADKSLSSYKGVRKGDCVVTFSRSGIFYVRREVE-SFAKKKCAMVYGALPPETRAEQARDFNNGRAEVLVASDAVGMGLNLKIKRMIFSSLHKFNLSLTQIKQIAGRA--GRFGDLPILRSLLHQPLDVPFENMSALAALLPKFSELLDHVLAKVVELTLSEMYAPVNGRDYHSLAMETLHKTLVLYIWLSYR Trire2 LDFRFPEWFPATR-MMQRTIHVHVGPTNSGKTYNALKALENSKCGIYAGPLRLLATEVYQRFKAKNICALITGEEVRSCTVESRFDVAVIDEIQMIADHDRGNAWTTAVLGVQAKEVHVCGEERAVNVIKAMCA-SIGDKCVVHRYERLSPLKTMDKALGDYSSLQKGDAIVAFSRLNLHSLKQRIE-EKTGRRCAIIYGSLPPEVRAQQAALFNNNDYDFVVASDAIGMGLNLEIRRVVLESVTKFDLTFPEIKQIGGRA--GRYRDLRSVQRAFQRTIQPPAGIVERFASYFPPLSYILKKIIADIIQLTIHDRYLPVALRALRALALESLHVAVNQYVWLSYR Umbra1 TDLRFPEWFPEAR-RMQRKIHLHVGPTNSGKTYSALKRLTEAKSGIYCGPLRLLAHEIFERMNNNGICNLVTGEEKRSSTVERDLEVAVVDEIQMMGDRTRGWAWTQALLGLRAQEIHLCGEESVVPLVKQLCE-AIDDEVTVHRYNRLTPLSISEKSLGSYGNVKKGDCVVTFARKDIFEVKKAIE-KETGLRCAVVYGALPPESRALQAKAFNASNFDVLVASDAVGMGLNLNIKRIVFESVQKYDIHPPHLKQIAGRA--GRFGDLSYVHEAMDTPIHPTLDIIEMFSAQMPPFSAVLQTFLAQSMDLSVRDRSAPTPLRDIIEMALESCHKIIMIYKWLR-- Ustma22 MDLRFPHQYPRAR-TLIRNIHLHVGPTNSGKTHGALVALSKARTGIFAGPLRLLAHEVWDRFNSGTVCNLVTGEEKRSCTVERAVDVGVIDEIQMIGDAQRGYAWTNAVLGLAAKELHLCGEASVIPLIENIAK-ACGDHLTIHRYDRLTPLSVADESINDLGQIQKGDCVVAFSRSGIFALKSDIE-KRTGLRCAVAYGALPPETKAEQAKLFNEGKLDVMVASDAIGMGLNLRIKRVVFDTLTKWNLSASQIKQIAGRA--GRYGELEILRAALASPIEPSSETLGQLSAMLPTLSQLYADVISPLIELTVAERNAPANTRDLCKAVLESLHRCYTLYLWLSFR Walse1 TDFRQPLKYSKAR-TMRRKLILHVGPTNSGKTHSALLALSRAKTGIYAGPLRLLAHEIFLRLNQGTICNLYTGEEVRSCTVEHEIDVGVIDEIQLIADDSRGPAWTAAVLGMRAKELHICGEETVVELLERIAK-ETGDEIIVNRYKRLTELRIGKP--STLKNVRKGDCVVTFSRSGIWALKRKIE-DATGLRCAVAYGGLPPETRAEQAKLFNDSGYDVMVASDAIGMGLNLKIRRVVFETVHKWNLSISQMKQIAGRA--GRYGDLQILERAISAKIGISTDALKDLNNLMPSLGDLIKTLMAAIANLPIDDAMAPCNTRDLCRFILESLHRSLVLYTWLSFR Zygro1 VDISNPEWFAEAR-KMKRHIIMHIGPTNSGKTYRALQQLKHANRGYYAGPLRLLAREIYDRFQKDGVCNLLTGEEVISGTVEQDFDVVVLDEIQMMADLDRGWAWSNALLGAKAREVHVCGEKSTLPLIKNIIK-MTGDKLTVNEYERLGKLKVEDWVLKGYKSLRKGDCVVAFSKKRILDLKLRIE-KDTNLKVAVIYGSLPPETRIQQAHLFNSGEYDIMVASDAIGMGLNLSIDRVIFTTDVKFNLSSSNIKQIGGRA--GRFKVLSTIRRGMDAPIWPTDEICGNIITKFPPPSVLLKAIVLAIFEIAFFDKNAPVKDLPFAQFCYESLYNIIMLYFWLGNR [Cluster1646.fasta_al_trimmed; alignment length = 246] Allma1 HVSVKFT-TARIPANFKRAALAEVVNPLPLDFLI-DGTLLRSSLAS-YL-DSHG-LSAENELVLEYLVALPPPTPVAAADDWISAVAVVSAGYDGVVRVAGV-VPLKA-AVAVAGMDQKVTIVDLAGHTGAIEALAHVLFTASWDGSIKVFSAKKARRALGSMY-GHVTALSSLFSGGHDHGVRVWDLATLLASGHAD-PVVRLWDVRLLSSAS-LDGTVKVLDVRSKRLCVAWVAAGGEDCELQV Ashgo11 QVKVKFF-TRFAPVSLKRYGLSEIINPVPFDFLI-DGQLLRCSLQD-YL-TRKG-LSSEAVLNVEYTRAVLPPSYLKSNEDWVSALDIVSGSYDGVVRTGHT-GAVRA-VLVSGGNDRTLRLWKLEGHQAPVVS--VDILSASYDNSIGFWSAKKRRKPLSLLE-SHVEQVIFAYSVSQDHTIKTWDLVTLLACGSSA-RHITLHDPRMLCSAS-HDGTVKVWDIRSKVFAVKWIISGGQDKKIQF Aspfu1 QVRVQLT-SKLVPTSLRRYALSTLVNPIPFEFLI-NGTFLRTSIDE-YL-TANG-ISAETTLEIEYVRALIPPLHIASHDDWVSSTDILSGSYDGLLRVGHT-ASIKA-AIASAGLDRTVRLWKLYGHKSGINSLAVHILSASSDNSVGFWSSSKRRKPLALLS-SHVSAAIFGYSASWDHSMRTWDLVTLLAAGTSA-RHITLIDPRGLISGS-HDGTCRIWDIRAKVFSVCWIVSAGEDKRIQI Aurde31 SQPVVFT-TRMLPSSWRRFQLSQLINPVPFDFLV-RGELLRGSLAD-WC-TERG-VGEEETVEIEYIEATIPPQHAATHDDWVASISFVTASYDGSVRVPHS-APVLS-AIASASHDRTARLTRLTLHSAPVASVVASLLTAGWDGLIGIWDSKKRRRPVDVMK-GHVSQAVFAYSCSFDSTIKAWDVRTTVVAASSD-RTLNLLDTRRVASGG-TDGVVRIWDVRSKVLSVSWIGVAGEGG-VEI Batde5 KIQAVFF-SRLVPTSLKRYGLSEIIGPVPFDFII-NGQFIKSSLQH-TI-DSHS-LSTENVLRIEFVEASLPPKNTAIQDDWISCIKILTGSFDNRTRVAHT-APIKS-VILSASQDQTISAFHCKDHRGSVESIVVSFATGSWDQTIRIWNSKKRQKSDTVLE-GHVTCVAFIFSGSLDHSVRVWDIESLIVTGHSD-NLVRLWDPRNLASGS-YDSTVKVWDVRS------------------- Botbo1 TIPIILK-TRMVPTTWRRFHLSQLINPVPFDFIA-NGEMISDSLGE-WC-DKNK-HGEEETLEIEYVQSVMPPQHMSSHPDWVSSISFLTGSYDSVVRLGHT-GPVSS-VIASASYDTTARLTLLHLHTAAVSSVTSNLLTAGWDSLIGLWTPRKRRKPSAVLK-SHVSKAIWAWSCGWDCTWRSWDVEITLAIASAD-RTVLLYS--HIISGA-QDGIVRMWDVRSRVLAVDWVGIAGEKG-VDV Botci1 QVQVHFS-TTLVPTNVRRYGLSQILNPIPFDFLI-NGTFLRTTLDE-YL-TANG-LSSETTLNLQYVRSLIPPLYEASHDDWVSSVDILSGSYDGLLRVGHT-SGVKA-AVASAGLDRTIRIWNLYGHTGSIDSIAVHILSASADGQIGFWTSTKRRKPLSLMD-CHATAVIFAYSASQDHTIKTLDITTIIAAGTTA-RHIALIDPRGLVSAG-HDGTCRVWDLRSKVFDVNWIVSAGEDKMVQV Caeel HVQITFF-SKDVPTGAECDDMNLLLNERRFEFLV-GETFLRTSLAE-FI-EEYE-VETETILKVECVIGIEAPKPLHDAPDWVSSVQIFSTTYGGDIVISAN-RLLKC-IFVVGGENQLLTLYALRGHERAVECVSVNAISGSVDTNLKIWNAKKRRKPMVTIG-GHVSAVEWAFSCSWDHTIVEWDLELLLISSCTD-AIPRLYDPKQFVSVS-TDKTAKMWDVRSRILCATWIATGSADCTIKI Canalb1 QIKIKFF-TNYVPVTLKRFGLSEVVNPIPFDFLI-DGVLLRTSIED-YL-TKNG-LSNEAFLTLEYTRAILPPSFLASNDDWISSIDILSGSYDGIVRTGHS-APVKA-VIVSAGNDRQVRLWKLEGHKAPVVDLAVDILSAGYDQNIGFWSSKKRRKPLSLLQ-GHVEGVIFGYSVSQDHTIKTWDLVTLIASGSSA-RHINLHDPRMFASSS-HDGTVKVWDVRAKIFDVCWIISGGEDKKLQI Cangl QVKVKFF-TRYAPISLKRYGLSEIVNPIPFDFLI-DGELLRTSLQE-YL-TKKG-LSSETTLTVEYTRAVLPPSFLANNDDWVSALDIYSGSYDGVVRTGHT-GAVKA-VIVSAGNDRSLRLWKLEGHKAPVVS--LDILSASYDNTVALWSAKKRRKPLSLLE-SHVEQVIFGYSVSQDHTIKTWDLVTLLACGSSV-RHITLHDPRLLCSAS-HDGTVKVWDVRSKVFAVKWIISGGQDKKIQI Capow EVQARFV-TSAVPTRLKRYGLSEVINPRPFDFLI-DGQFLRTSLDK-YI-AEHA-LSRETILEIEYCEAVPPPAPLHSHEDWVSSISFLTGCYDGALRAKHT-APIKS-TLVSASMDHTLLAWKLAGHTESVDVVDSHVCSGSFDKTIKLWTVSKKARALSTLV-GHVTGVAWIHSASMDCSVRAWDVETLIITGHAD-EAIRVWDPRQFATGS-YDNTVKLWDLRSRVLCVNWIGSGSVDKTLQL Catan2 QVQVKFF-TSLVPTAFKRRALSEIINQVTFDFLI-DGVLLRTSLDS-YL-SQHG-LSAENTVSIEYMVSLPPPKPVAAADDWISAVSFVTAGYDGVVRM-GT-APLKA-LVAVAGMNQKVSIMDYSSH----------LYTASWDGSIKVYSTKKAKKALGSLT-GHVNSVAA-----------------LIASGHAD-PVIRLWDSRHLASAS-LDGSVRVFDIRSKRLCVTWVASGGEDCQLNV Cioin HFQIKLF-TQSVPGSSTCTELNDLVNRSDFDFLV-NDEFIRTSLVD-HV-ETKG-LSSESVIDVEYLQRKQAPELKHSQPDWISSIKIITGSYDCAVTVGHS-EPVKS-IFVSTSQDQHAVIWTCKGHSKSVECAASNFATGSWDSTIKVWSSKKKFKAKVTLS-GHVSALTWICSGSWDHTIRIWDIDTLVVTGNTD-RHVRLWDPRTLVSGS-LDNCVKMWDTRSKVMSVDWVASGGADCKVFT CocheC53 KVQIRLT-TRLVQTSLTRHKLSTLVNRIPFDILI-NGEFLRTTIDQ-FL-TKNG-INAEATLDVEYTRALVPPLNVTSHDDWVSAVDILSASYDGLLRVGRI-TSLKT-AMVAAGLDNTVRVYKLFNHRWGVEDVAVHILSASSDTTVSLFSSNKRQKALATFT-GHVSSVIFAYSASHDHTLKTWDLPTLLATGTSA-RHITLVDPRNLVSAS-HDGTVQIWDLRNKVFTVCWIVSGGEDKRVQI Coere1 QMQIRLV-TKVVPQQLQRYGLSEIVNPVPFDFLA-DGQFLRESIGS-YL-KERG-QSAENILTLEYVESMLPPTEIASHDDWISSVAFVVGSYDGVVRVGHS-SAVKC-VAVSGSQDRTAIAWGARGHTDSIEAVAVNFVTASADSTIRFWSAVKRQRAIGTLS-GHVSSVCFVFSGGWDHSLRTWDVASLVATGNTD-RCVRLWDPRLLASAS-HDSSMKIWDIRSKLLALDWLLAGGESGSLRI Conco1 RIRVKFY-TQFLPINLKRLGLSTVINPVPFEFLI-NGQILKGSIDN-YL-KSNN-LSTENVLELEYLESVLPPTPQAQHDDWISTIDIATGSYDNIIRLCHT-GPIKA-IFLSASLDQTIVAWKAIGHTKSVESVKVSFATSSLDGTIKLWNSAKKTKSIMTLG-DHVSSIQFLYSGGWDHSLRTWDLTTLLASGHTD-RLIRLWDARQLISSS-YDGTIRGWDIRSKVLCVNWIVSGGDDQVLGI Conpu1 THPVIFT-TKMVPLAWRRYHLSQLVNPVPFDFLV-QGEILRGTLQE-WM-VERG-VGPEETLEVEYVESVLPPTKAAESEDWEAGVTFATASYDGHIRVIHP-APITS-LILTSSHDLTARLSTLHLHTAPVSHVTVSVLTSSWDTLIGVWDRKKRRKPTAVLK-SHVSAAAFAASVGFDATVRTWDVENNAFAASTD-RNVSLFDLRQLISGA-YDGVVRLWDVRSKVLSVDWVAVAGEGG-VGV Copci NQAVVFS-TQMIPTTWRRYHLSQLVNPVPFDFLV-KGEILRTTIAE-WC-AENG----EETLEIEYIESVLPPQRLSEHESWVSAVSFLTTAYDGHLRALHS-APITS-FIATSSQDLTAQISELHLHTAPVSSIASNLLTSSWDSLIGVWDTKKRRKPLTVLK-SHVSKVAWGVSCGFDSTLRTWDVERTALAVSTD-RTMMLYDLRQVVTGA-YDGVVRVWDTRSKVLAVDWIGIGGEGG-LDV Croqu1 MIPVRLV-TKMVPSDWKRFQLSELINPIPFDFVI-EDQLLRTSVKA-FI-DSRG-LSSETVLEIEYLESVLPPKYINSHDDWISHLDFLTACYDSNLRLGHD-QPVLS-TLASGGMDRVIRVWKLALHKSPVSTIKASLITGDWDGTIGLWDSKRRKKPLQILT-SHISRAVFAFSASHDHSVKRLDLETLLVTGCMD-RTVCFWDVRQILSGS-YDGTCKIWDTRSKILSVGWLGFGGEDCELSI CryneH991 QLPINLF-TRFIPSAWRRFQLSELINPVPFDFLV-NGEVLRGSLEA-WVKKNRG-GDEESQIDVEYVRSVMPPEEAARVEDWVSGLSVLLSSYLSHLQVGAT-----S-CVAAGGVDRQTHVYSLHGHTSPVSSVIASIVTGSWDGNINLYVTKKRRKPDAVMR-GHVGGLVWIWSAGWDGSVRGWEVETTLATGNMD-RTICLWDTRTLASAT-YSGVVQIWDIRSRLLAVDWLVAGGEDGEVGI Crypa2 QIKVTFT-TTLVPADIKRLGLSRILNPVPFDFLI-NGTFLTSTLEE-YL-EREG-LSFETNITLQYVRSLIPPQYEASHDDWVSAVDILSASYDGLLRIGHS-ASVKA-AIASAGLDRTVRVWKLYGHRSTIDSLEVDILTASADGSIGLWSASKRRKALHLAA-FHATAAVFAYSAGQDHDLHTIDLTTLLAAGTSS-RNVVLVDPRSLVSGS-HDGTCRIWDLRSKVFSVVWIVSGGEDKRVQI Debha1 QIKINFF-TNYVPVSLKRYGLSEIVNPVPFDFLI-DGVLLRTSLED-YL-VKNG-LSSEASLNLEYTRAVLPPSFLASNDDWISSLDILSGSYDGIVRTGHS-GPIRS-VIVSSGNDRQVRLWKLEGHKAPVVSLAVEILSAGYDKAIGFWSSKKRRKPLSFLE-GHVEDVIFGYSVSQDHTIKTWDLVTLLVCGSSA-RHINLFDPRMFASCS-HDGTVKVWDVRSKVFSVIWIISGGQDKKIQI Dekbr2 QVKIKFI-TRFVPVTLKRFGLSEIVNPIPFDFII-NGTILKGSLHD-YL-LQNG-LSSEAFMTVEYTRALLPPRFLASNEDWISSIDILTGSYDGIVRIGHR-QPVKA-VFVSAGMDRDVRLWKLSYHKSSISSLAVNIISGSYDNTLAIWSSRKRLKPLAVLE-SHVEDVIFGYSVSQDHTVKTWDFVTLLATGSSA-RHINLHDPRMILSGS-HDGTVKVWDVRTKVFAVGWIISGGNDKKLQI Dicdi KVKVKFI-TNAVPVRLGRLGLSEVIH-KPFDFLI-NGKFIRTTLDK-HI-KNAN-LSEEQIITIEYLEAITEPKREKEHDDWVSCVDVVSGSYDLGVRVGHL-AGVKS-VFVSASMDKTLRVWNLKEHTGTIESVYVSIVSASMDSTIKLWSNSKKRRSLASVTVPNVTVVNWMLSGSMDSKIRLWDVSTLIVTAHKD-RIVRIWDPRHCCSTS-HDGTVKYWDIRTKVLSSSFIVSGGTDSKLRI Dmel QVQVHLK-TKAIDGTVTTVELNTFVNT-DFDFLV-FDEYLRGRLCD-HL-REKA-ISFEDAIEIEYVERFPAPEPQDCHDDWVSAVKILSGCYDNTLNLGHT-APIKA-VFVSTSQDQTAMLWQCKGHERGVDSVSVSFATGSWDTMLKVWSSSKRMKPKITLQ-GHVSAVQWLLTGSWDHTLKVWDLSLLILTASAD-KNLRLYDPRLFVSGA-YDNQNKLWDCRSKVLDIDWIVSGGVDNTVRV Enthi TILVRFS-TKNVPSDSNRLALSRLINVVPFDFIV-GGEFLRTTLQE-HL-KEKN-IPIESTVDIEYTVALPAPQPEWYQENWVTSLSQSISANNESGI-GTTKRPVKT-IVACGGKSNNIHIFSLTGHNGSIESLCYSLVSGGWDKKVNVWDKRSRSN-------GHTHCI-WILSSSLDGTIAIWDIQNLIATGHND-SIIRLADPRLLASAG-YDNSIKIWDIRSKMTAVCWFYSAGANGFMKA Falba T-------TSAIPASLRRYGLSEILNPRPYDFII-NGHFLRTSIAE-WI-KAND-ESSENVITIEYVESLTPPKTIEQHDDWVSSIVV-SGSYDSQLRLLPK-RSIKAITVASASKDQNAHVWSLVGDGHSVEAITASIATGYWNGAIRIWDSSKKRKHLIELSGGHITALHWLYSGSWDESLLEWNVAMLVATGHADIRSIQLWDPRLLASAS-RDGTIRIWDMRA--LAVNWVVSGGSDGRVKF Fomme1 TLPVLFT-THMIPASWKRYQLSQLVNPIPFDFIL-KGELLRGSLQE-WS-EATG-VGTEETLEIEYVESLLPPTRIAGHDDWVSDVSFVTANYDGLLRVGHN-AAVTS-VVASASHDRTARLT-LHLHTSPISSILSSLLTAGWDNLIGLWDSRKRRRPSAVLK-SHVTAAIFAYSASLDATVRTWDIDTLLAASSTD-RTVRIIDTRHVASGG-YDGVVRVWDVRSKVLGLDWMAVAGEAG-LDI Fusgr1 QVKVVFT-TTLVPADIKRYGLSRILNPVPLDFLA-NGTFLRTSIEE-YL-ATHG-LSSESTLTLQYVRSLLPPVYEASHDDWVSGVDVASSSYDGLVRIGHT-QRANV-VLASAGLDRKVIVWDLWGHEKDINSIDVNILTASSDGKVGLWTSTKRAKPLALIS-VHVTAAIFAYSASKDHTVRTIDLTTLIAAGSSA-RHITLLDPRSLVSGS-HDSTCRVWDLRSKVLGVSWIVSGGEDKKVQI Galma1 SQPVSFR-TEMIPTSWKRYQLSQLINPVPFDFLV-RGELLHTTLSE-WC-AENG-VGEEETLEIEYIESVMPPQKMSDHEDWVSSVSFFTASYDGQIRVAHA-APITS-LIATASQDLTAQLTELHLHTSTVSSISANLLTSSWDGLIGLWDRRKRRKPLLVLK-SHVSKVVWAYSCGFDSTVRMWDTEYSILAVSSD-RTMSLYDQRQVVTGA-YDGVVRVWDLRSKVLSVDWVGVGGEGG-LEV Ganpr1 KVQVRLT-TNLLPSSLGRFGLSEVINPTPFDFLI-NGRLLRTSIKE-FS-EEKG-LSLEAVLEVEYILSSQPPALAASQDDWISDVAILTTSYEGLARVGRR-KPLRA-AGLVGSDDGVVTMWESGEHMAGVTDLAVSFASSSTDGKILLYSRTKRRKSILSLE-KSVSSVCFIYSGGWDHAVRGWDVETMLATGHAD-GVVRIWDPRHVAAGS-HDGHVRIWDLRSKVLAIDWLVSGGEGRNVDM Gloin1 QVQVRFV-TKIVPAKLKRYGLSEIINPLPFDFMI-DNLFLRTSLLE-YL-ENSG-LSTENIITIEYVESMLPPTPLSSHDDWISSVKFLTGSYDNHVRIGHN-APIKS-VFLSASQDRTIRAWRCIGHKGSIESIAVSFASGSWDSSIMLWTSSKRRKPIATMN-GHISSVVFLYSGGWDHSIRIWDVESLIASGHSD-RIIRLWDPRMLVSGS-YDGTVKIWDIRSKIFCVDWILSGGEDNQLHI Hisca1 QVRLKLT-SRLVPTGLRRYALSTLVNPIPFEFLI-NGTYLRTSIDE-YL-TANG-ISAETTLDVEYVRALVPPLHVASHDDWVSAVDILSASYDGLLRMGHT-ASVKC-AIISSGLDRTVRLWKLYGHKGSVDSISMHILSASADHSVGFWSSSKRRKPLALFK-SHVSAAIFGYSTSWDHSLRTWDLVTLLASGTSA-RHITLIDPRGLISGS-HDGTCRIWDVRSKVFDVCWIVSSGEDKMIQI Klula1 QVKLRFF-TRYAPVSLKRYGLSEIVNSMPFDFLI-DGELLRTSLQD-YL-IKKG-LSSETFLNVEYTRAVLPPSYLSSNEDWVSSLDIYSGSYDGIVRTGHS-GPIRA-VLVSAGNDRTLRLWKLEGHKAPVVS--IDILSASCDNTVSLWSAKKRRKPLALFE-SHVEAVIFGYSVSQDHTIKTWDLITLLACGSSA-RHITLHDPRMICSAS-HDGTVKVWDVRSKVFAVKWIISGGQDKKIQI Lacbi2 SQPVVFT-TQMIPTTWRRYQLSQLVNPVPFDFLI-KGEIIRGSLAE-WC-SEHG-VGEEETLEIEYIESVMPPQKMSEHEDWVSSVSFLTASYDGNLRAAHP-APITS-LIASASHDLTARLTQLHLHTAPVSSISANVLTASWDGLIGYWDSKKRRRPLSVFK-SHVSKVLFAYSCGFDSTVRRWDTETSALATSTD-RSMTLYDLRQVVTGA-YDGVVRIWDLRSKVLSVDWVGVGGERG-LEM Lenti61 THPVVFT-TQMIPTTWKRYQLSQLVNPIPFEFLI-RGEILRGTLAE-WC-AEKG-VGEEETLEIEYFESLMPPQRMSTHEDWVSSVSFLTASYDGAIRVTHS-APISS-IIASASQDLTARITHLHLHTAPVSSVSASLLTSSWDGLIGLWDRKKRRKPAAVFK-SHVSRVLFAYSCGFDSTVRTWDVENTALTASTD-RSVSQYDLRQLLTGA-YDGVVRLWDLRSKVLSVDWAGVGGEGG-LEV Malgl1 TVPIRLR-TSMVPVTWRRSQLSTLVNAVPFDFIV-DGSLLRCSLDE-YL-EQRG-QSAETTLELEYIRSTLPPAFKDAQDDWVSSVDILTASYDGIVRIASN-VSLTS-AIVTGSMSGTVAVWRI---DVAVAATNASIVSAGWDGSIALWDGKKRRKPLMVL---HTAARALIWSAAWDGTVKYWDVVAQLVCGHMD-HSLALYDFRLFASGA-YDGRIKVWDVRSKVLGLDWLVSGGEDCRVCL Mellp23 MIPVRLV-TKMVPSDWKRFQLSELINPIPFDFVI-EDQLLRTSVKT-FI-DSRG-LSTESILEIEYLESVLPPKYVNSHDDWISHLDFLTACYDANLRLGHD-QPILS-TLASGGMDRVIRVWRLALHKSPVSTIKASLITGDWDGIIGLWDSKKRKKPIQVIN-VHVARALFAFSASHDHSVKRLDLETLLVTGGMD-RTVCFWDVRQILSGS-FDGTCKIWDTRSKILSVGWLGFGGEDCELSI Mnele QIQIKLK-SASVSSNSSQTELQQLVKI-EFSFRV-GEEILQNTLRK-YC-ESCN-FSGEAVLEIDYQEKRKAPDVSDVLDDWLGGVACFAGLY------VHN-KPIKS-ILVTTSLDQNL---CLRGHTETVTCCSVSIASGSWDTHLKVWSVSKRRKPLLTLG-GHITGICWLITSSSDMSVKIWDTQLLIAAGSSD-KYVRLFDPRELVSGS-YDGRSLLWDIRSKVLCCDW-LSGGSDSKLHI Monbr ELRISLF-TTAVPANLRRRGLSSLINPKPFDFLI-EHEYLRSSLLDHVL-QSQK-DGAEAIIKVEYTLAMPPPQPGPSHEDWVGGLALATASYDHHGRLGHT-RPVLG-VVATGGMDQAVRIWQGLGHRGTVQCVAAQVASGSWDHEIFLWSGNKRRKPL-----GHVHDMAWLYSVGGDHAVRQWDVEATVATADVD-GAARLYDFRQVAVCG-DEAPIKIWDRRSRMLALTWLFAGGAS--KRV Morel2 QVQVKFV-TQQTPARLRRYGLSQIINGAPFDFLI-DGEFLRSSLAE-YL-EEKN-MSTENVLTIEYVESMLPPTPLSSHDDWVSAVQFLTGSYDNHVRLGHN-GAVKA-VLLSGALDRSILAWECRGHTGGVESISLNFASGSADATIKIWTRKKRKTPISSLN-AHVSAVTFLYSGGWDHSVRVWDIENLLASGHAD-PVVRLWDPRMLASGS-YDGLIKVWDIRAKVFSIDWLLSGGEDNQMKI Mucci2 QVQVRFT-TQLLPSNIKKEGLSEIVNPIPFDFLI-DGQLLRTSIVE-YL-NAAQ-LSTENLVTIEYVESMLPPIPLTAHDDWISSVKFATGSYDNMVRLGHS-DAVKS-V-FSGSLDHTVLGWECKGHKGPVESVAVDVASASADGLVKIWSKKRKKNKAVSLE-GHVNAVDFVYTGGWDHSIRSWDVEQLLATGHSD-NTVRLWDPRALCTGS-YDSTVRVWDIRSKVLSVFWILSGGEDKKLRI Mydma HVQAKLY-TKSIPSISGTLELNALIKILEFDFLINGEYFEADSLAS-YI-SEKN-ISTESVIEIEYILKQKEPKLEKSHNDWVSSIDIITGTYDSLVNISHS-MAVKH-VFLSASQDQSVLIWMCRGHAGSVDCLALHFASGSWDKMIKIWDTKKSKKPLITLS-GHVSSLLWLVSAGWDHCIRFWDCETLLASGSTD-KYIRLWDPRHLVSGS-YDNSVKLWDIRSKVMCVRWVLSGGADSQVHI Neucr2 QVRVTFT-TQLVPADIRRYGLSRILNSIPFDFLV-NGSFLRGSLEE-YL-NANG-LSLETNITLQYVRSLIPPTYEASHDDWVSAVDILSASYDGLLRIGHT-ASIKA-AIASAGMDRTVRVWKLYGHTSSIDSLEVDILTASADGSIGFWTTSKRRKPLALMN-IHATAAVFAYSVSQDHTVKTIDLTTLLACGTSA-RHITLVDPRSLVSGS-HDGTCRIWDLRSKVFSVVWIFSGGEDKKVQI Orpsp11 KVQVRFT-TQMIPIQFKKSSLSQIINPIKFEFLI-DGKFLKGSLKK-YL-DDNN-LSSENQLLIEYIEAMQPPKSLPSHDDWIGSVSILTGSYDKIARIGHT-APVKS-VCLTGSNDNTIRIWECKGHEGTIEDIAVSFATASYDSNIKIWGKQKKRKSMATLK-GHVTCLVFLYSGGNDHSLRFWNIEALLATGHSD-KFIRIWDSRMLVSGS-YDSSVKFWDIRSKVLCVDWVATGGSDTILRL Pench1 QVRVQLI-SQLVPTGLRRYALSTLVNPIPFEFLI-NGTFLRTSIDE-YL-VDNG-ISSETTLEIEYVRALIPPLHIASHDDWVSATDILSGSYDGLLRIGHT-ASIRA-AIASAGLDRTVRLWKLYGHKAGIESLAVHLLTGSADNNVGFWSNTKRRKPLALLS-AHVSAAIFGYSASWDHSLRTWDLVTLLAAGTAA-RHITLIDPRGLISGS-HDGTCRIWDIRSKVFSVCWIVSAGEDKRIQI Phybl2 QVQVRFV-TKLVPANFKRYGLSEIVNPTPFDFLI-DGEILRTSIAD-YL-FSKS-LSTENIITIEYVESMLPPTPLTAHDDWISSVKFLTGSYDNNVRLGHS-DSVKS-VAYSGSLDYSLLGWECKGHKAAIESVAVDIASASADSTIKVWLKKRKKTRAMTLE-GHVNSVVFVYSAGWDHSIRSWDVEQLAATGHAD-NIIRLWDPRTLCSGS-YDSTVRIWDIRSKVFSVHWVLSGGEDKKLRL Picst3 QIKIKFF-TNYVPVSLKRYGLSEVVNPIPFDFLI-DGVLLRTSIQD-YL-TKNG-LSSETFLSLEYTRAVLPPSFLASNEDWISSLDILSGSYDGIVRTGHS-GPIRA-VIVSAGNDRQVRLWKLEGHKAPVVALAVEILSAGYDHSIGFWSSKKRRKPLALLD-SHVEDVIFGYSVSQDHTIKTWDLVTLLATGSSA-RHINLHDPRMFASGS-HDGTVKVWDIRTKVFAVSWIISGGQDKKIQI Plicr1 SQPVVFT-TQMIPASWRRYQLSQLINPVPFDFLV-RGEVLRGSLGE-WG-AEHG-AGEEETLEIEYIESVMPPQKMSSHEDWVSSVSFLTASYDGHIRAAHT-GPITS-LVASASHDLTARLTRLHLHTAPLASIASNLLTASWDGLIGLWDRRKRRKPVTVLK-SHVSKAVFAYSCGFDSTVRTWDVDNTALAASTD-RTISLYDLRQVVSGA-YDGVVRVWDLRSKVLAVDWVGVGGEGG-MEI Polpo KVKVRFV-TNGVPERIGRLGLSELVNHKPFDFLI-NGQFIRTTLDK-HI-KKAG-LKEEDTITIEYVEAVTEPKREQEHDDWIASVDALTGGYDFGARIGHQ-AAIKS-VFLTASLDQTIRYWHFKAHQGSVESVASNFASGGYDNKLRLWDNKKSRKSLSTLE-KHITTIDWLISGGMDKSIRLWDLETLIASGHAD-HTIRLWDPRQLLSAS-HDGTVKLWDTRSKVLSCDWIISGGADTKLKI Pucgr2 MITVRLT-TKLVPSDWKRFQLSQLINPVPFDFVV-NDQLLRTSVKN-FI-DSHG-LSTESVLEIEYLESVLPPKFIQSHDDWISDLSFLTASYDSNLRLGHE-QPVLS-VIASGGLDRVVKIWELPLHKSPVSTVQSCLLTGDWEGILALWDLKRRRKPVQIIN-AHISRAIFVFTASHDHTVKRFDLETLLVTGCMD-RTICFWDCRQILSGS-YDGTCKIWDTRSKILAVGWLGSGGEDRKLAI Punst1 SVPVIFH-THFIPASWKRYQLSQLVNPIPFDFLI-DGEILRGSLGE-L-----G-ANTEETLQIEYIESVMPPQKMSSHEDWVSSISFVTASYDGHLRTLHA-APITS-AVATASHDLTAHLTSLHLHTAPLSSVSSNILTTSWDGLIGVWDNRKRRKPTAVMK-SHVSKAVWAYSCGFDSTVRSWDVEMTALTASTD-RFVTIYDLRQVVTGA-YDGVARIWDFRSKVLGVDWIGIGGEGG-MEV Rhior3 QVQVRFV-TQLLPSSIKKEGLSEIVNPIPFDFLI-DGQLLRTSISE-YL-NATN-LSTENLVTIEYVESMLPPVPLTAHDDWISSVTFATGSYDNMVRLGHT-DSVKS-VVFSGSLDHSVLAWECKGHKGPVESVAVDLASASADGLVRVWTSKKKKKRSVALE-GHVNTVAFVYTGGWDHSIRAWDVEQ---------------------------------------------------AKFRN Rhoto1 QIAIRLS-TKLVPASWRRFHLSELINPVPFDFLI-DQTLLRSSLGA-YC-AATG-TSEEVVLEVEFLPSTLPPRLESTSEDWVSDVSVLTASYAGTLSLGHD-LSALS-AVASGGMDRVGRVWELSLHQAPIASVRSRLLTAGWDGLVGLWDKKKRRKPMAVLR-GHVSRAVFAYSAGWDHSVRSWDLTILLATGSTD-RLICLWDLRLFASGS-YDSTVRIWDARSKVLAIDWLVAGGEGSRVIT Rozal11 TVQVKFF-TSVLPTNLKRLGLSEVVHRIPFQFLI-NKEILSTSIQE-YV-EENN-LSTENVLLIEYMPADTPPEEKDCHDDWISALKYITGCYDGQIYVVHK-KPIKC-IIVSGSLDRTISVNRGIGHKNSI------IASGCFDSTIGIWSTVEKKKCVTFME-GHVTQAC------------------WLASGHAD-GIIRIWNPLVLCAGS-YDGSVRTFDLRHKVFVCEFLLFGGEAKKLNI Sacce1 QVKIRFF-TRYAPISLKRYGLSEIVNPVPFDFLI-EGELLRTSLHD-YL-TKKG-LSSEASLNVEYTRAILPPSYLNSNEDWVSSLDIISGSYDGIVRTGHS-GPIRA-VLVSAGNDRTLRLWKLEGHKAPVVS--IDILSASYDNSIGFWSARKRRKPLSLLE-SHVEQVIFGYSVSQDHTIKTWDLVTLLACGSSA-RHITLHDPRILCSGS-HDGTVKVWDVRSKVFAVKWIISAGQDKKIQI Salro ELRISLT-TQTVPGSATRAQLSKLVNPLPFDFIV-NEQFLRSTLAD-VV-QEHN-LQAEEELSVEYVLALLPPQP------------QATAS------------------------------------------------------------------------------------------------------------------------CG-L------------------------------ Schco3 SHPVVFT-TQMLPASWRRYQLSQLVNPVPFDFIV-RGEVLRTTIGE-WC-AEHG-VGEEETLELEYIESVLPPQKMSDHEDWVSSVSFLTASYDGHVRALHG-APITS-VIASSSHDLTAQLSRLHLHTQPLSSIASNLLTSSWDGLIGLWDRKKRRKPLSVLK-SHVSRVVFAYSCGFDSTVRVWDVENTVLAASTD-RTVAVYDTRQAMTGA-YDGVARLWDLRSKILSIDWAAIGGEGG-LEV Schpo1 QVQVRFT-TRFVPTSLKRYGLSQIVNPTPFDFLV-QGQLLKTTLDE-YI-VQNG-LSTESILDIEYIQSTLPPAYLASHDDWISGIQILTSSYDGIARVGCG-SSLKS-AFLTASLDQKIFHWVFVGHK-DIVERVRSFISASADNTVGIWDKKRRRKPLILCE-GHVMDIVFAYSVGQDHTIKTWDLITLVICGSSA-RHIVVHDPRMFASVS-HDNTCRVWDVRAKLFAVDWIVTGGTDKQLQI Sorma QVRVTFT-TQLVPADIRRYGLSRILNSVPFDFLV-NGSFLRGSLEE-YL-NANG-LSLETNLTLQYVRSLIPPTYEASHDDWVSAVDLLSASYDGLLRIGHT-ASIKA-AIASAGMDRTVRVWKLYGHTSSIDSLEVDILTASADGSIGFWTTSKRRKPLALMN-IHATAAVFAYSVSQDHTVKTLDLTTLLACGTSA-RHITLVDPRSLVSGS-HDGTCRIWDLRSKVFSVVWIFSGGEDKKVQV Sphar TVQVRFVPSDAVPETLRRYALSEIVNPIPFDFLV-DGMLLRTSVAK-YL-ESHA-LSRETIVKLEFFMATPAPEASTEHDDWVGALDILTGSYDGVVSLEHT-GGIKR-LFVTASLDHSLRVWG--GHTGSVEGVAVSCVSGSFDKTLRVWSGKKKRKASLVLE-GHVTSVVYVYSASWDHSIRQWDINSLIVSAGAD-KAVRLWDPRQFVSAA-YDGDIKIWDARSKVLCVAWILCGGDDNRVHI Spipu1 QVQVRFR-TRLVPARLRRYGLSEIINPIPFNFLI-DGKFLQTSLKT-YL-DNHG-LSTENIVELEYVEATLPPSPAAAHDEWISSVRVLTGCFDTLGRVGHS-GPIKS-VFVTGGQDAKVFGWECVGHTGSVEGVACSLATVSWDGCVLLWNSRKRRK----LT-GHISCVTFLVTGGWDHTVRAWDVEQLIVTGHSD-GVLRLWDLRTFVSGS-YDSTIKVWDIRSKVFGVDWIFSGGEDALLRS Sporo1 QIAIRLS-TKLVPASWRRYQLSELINPVPFDFLI-DQTLLRSSLGA-YC-QQTN-TSEEIVLDVEFLPSTLPPQLDSQAEDWVSDVDILSASYAGTVSLGHD-LSVLS-TIASGGMDRIARVWELSLHQAPISSVRSRLLTAGWDGLIGVWDKKKRRKPMTVLR-GHVSRALFAYSAGWDHSVRVWDLAHLLLTGSTD-RLLSLFDLRMFVSGS-YDSTIKLWDARSKVLCVDWIVAGGEGAKVAV Stehi1 SIPVVFT-TKMIPSTWRRYQLSQLINVIPFDFLI-GGEVLKGSLEE------RA-AGEEETLEIEYIESVMPPKRMANHEDWVSDISFLTSSYDGSIRVLHT-APITS-IVATASHDLTAQISELHLHTAPLSAIHSNLLTSSWDGLIGLWDRKKRRKPSAVLK-SHVSDVQFAVSCGFDSTLREWDVENSALAAATD-RTVTLYDLRQFVSGA-YDGVVRLWDLRSKVLGVDWVGIAGEGG-VEV Tapde11 SVQVRFT-TKLVPTSLKRYGLSEIVNPIPFSFLI-EGELLGTSVEE-YL-TRRG-LSSETTLEVEYIRSILPPSFLASHDDWISGIAIVTGSYDSVLRVGHS-SAVKA-ILVSASMDRTLRLWSLRGHKTSVESCDFYVVSGSADGILGIWDQNRRKRPRQLHP-IHVSRVAYVYSAGWDHTLVTTDLTTVLSGGQ---RNIQIHDLRLFASAS-FDGEVRVWDLRNKVMAVAWIVSGGEDCLLQI Thetr TLQVQLV-SRSVPISSTRYALSELVNAVPFDFMI-DGTFLRTTLEG-YVLESKGTLSAETVLVIEYTEALARPQPDVLQDDWIADLALASASYDGLVRIGHK-AAVKA-VLVSAGRDHGVALYETGAHDDTVESVAFHFITGAWDGKVQVYNPAKRAKPLITLE-GHVTTALFALSASWDHSLRVWDVPSATLTAHAG-PVVRLWDFRHFATAA-HDGKVRVWDIRSKVFSLAWILTGSADCTVSR Treme1 QLPINLF-TRLIPGSWRRYQLSELINPVPFEFIV-EGEVLRGSLEA-WI-KSRG-RDEETVVNVEYMESVLPPKQEGTQEDWVSGLSILVSSYLSHLRIGAS-----C-CLAAGGIDRSIHVFSLMGHTAPISSLTVSLISASWDGNLHLYS-KRRKKPDGMMR-GHIGGVVYVWSSGWDGSVRGWEVETVIVTGNMD-RTVCLWDTRTLSAIT-YSGQIQIWDIRSRLLAMDWVVAGGEDGEVGV Trire2 QVKVVFT-TDLVPADIKRYGLSRILNPVPLDFLA-NGTFLKTSIEE-YL-KSNG-LSQETTLTLHYVRSLLPPVYEASHDDWVSGVDVASSSYDGLVRIGHT-QRINA-VLASAGLDRKVVVWDLWGHEKNIHSIDVNILTASSDGRVGLWSSTKRAKPLAMIP-LHVTAAIFAYSASLDHTVKTIDLTTLVAAGSSA-RHITLLDPRSLVSGS-HDSTCRVWDLRSKVLSVVWIVSGGEDKKVQI Umbra1 QVQVRFT-TQFVPANFKRYGLSGIVNPIPFDFLI-NGELLRTSLSQ-YL-VANN-VSSENVISIEYVESMLPPTPVSAHDDWISSVKFLTGSYDSMVRLGHA-DAVKS-VVYSTSLDQTVIAWECKGHKGSVEAVAVDFATASADATVKVWGKKRRKTFCQTLN-GHVTSVIFVYTGGWDHSIRSWDVEQMVATGHGD-KIIRIWDPRTLCSGS-YDSTVRVWDIRSKIYSVHWILSGGEDKKLNI Ustma22 TVPIVLT-TSMVPVSWRRTHLSTLVNAIPFDFIV-HSSLLRTTLGE-YL-ESSG-LTSESTLTIEYVRSTLPPTRLAAHDDWVASIDYMTSSYDGSVRLGKN-TSLCS-ALVTGGMDGRVQLWSV---DTAQGPQGSSVLSAGWDGIVAVWDTSKRRKATMIL---YTGAKNVAWSIGYNGVLKGWDLGSTLAVGSMD-RAIHLFDTRLFASASGLECGVKVWDARSGVLALDWVVAGGKDKRITV Walse1 NVPVILH-SIMIPSNWKRYQLSQLINAIPFDFFV-GGGKLSSVLSE-I---SNG----EETLHLSYIPSILPPKHLSTHDDWISSVSFLTGSYDGLASIGHN-GPVLD-L-VTAGQDSTLKLWDYTGHKNAVSSVRSAVLSADWDGLVCLWDTKKRKKPLHQLR-GHVNGVAFGYTGGADHSLKSWDLGVTIVSGHVD-RSIALWDMRHFASAG-MDGNIKLWDIRSKILGLAWLASGGEDCALQL Zygro1 QVKLRFF-TRYAPIALKRFGLSEIVNPVPFDFLV-DGELLRSSLQD-YL-TKKG-LSSETLLNVEYARAVLPPSYLASNEDWISSIDIISGSYDGIVRTGHA-GAIRS-VIVSAGNDRTLRLWKLEGHKGPVVS--VDILSSSYDNSLGLWSARKRRKPLSLLE-SHVEQALFGYSVSQDHTVKTWDLVTLLACGSSA-RHITLHDFRMLVSGS-HDGTAKVWDIRAKVFAVKWIISGGQDRKLQI [Cluster1679.fasta_al_trimmed; alignment length = 215] Allma1 YPWNHSFDHASIRRGYQVYKEVCAACHSLDRIAYRNLVGVSHSVDEAKALAEEMEYVDGPNDQGRPGKLSDYHPRPYPNEEAARAANAGAYPPDLSLMVKARHGAEDYVFALLMGYCD-PPAG-VEIREGLNYNPYFPGGAIGMARNIYDEVVEFED-GTPATASQIAKDVVTFLAWAAEPEHDDRKRMGLKAMILLTAMKRFKWSVLKSRKVVF Ashgo11 YGWSHTFDHASIRRGYQVYREVCAACHSLDRVAWRTLVGVSHTNQEVRDMAEEFEYDAEPDDQGRPGKLADYIPGPYPNEQAARAANSGAVPPDLSLIVKARHGGADYIFSLLTGYPEEPPAG-VQLPPGTSYNPYFPGGAIAMGRVLFDDLVEYED-GTPATTSQMAKDVTTFLHWCAEPEHDERKRLGIKAVVLLSSLKKFKWAAVKNRKFVF Aspfu1 YPWEHTFDHAALRRGFQVYREVCASCHSLTRVPWRSFVGVMHTVDEMKAFAEEHEYDTEPNDQGRPGKLSDYIPPPYKNEEAARAANGGALPPDLSLIVKGRHGGCNYIFSLLTGYPDEPPAG-AQVAEGMNFNPYFPGTGIAMARVLFDGVVEYED-GTPATTSQMAKDVTEFLNWAAEPEMDDRKKMGAKALVILTGLKRYKWAPIKTRKIVY Aurde31 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 WPWETTFDHASLRRGYQVYREICAACHSMDYIYWRNLVGVTHTENEAKEMAAEYEYKDGPDDKGRPGKLTDPMPRPYPNEESARVANAGSYPPDLSCIVRARHGDADYIMSLLLGYCE-PPAG-ISMREGLHYNPYFPGGAIGMARSIYDEVVDYED-GTPNNASQLAKDVTTFLTWSSYPEHDQRKKMGLKTIAIASTIKRFKWSHLKSKKIVF Botbo1 YPWSHTFDHASIRRGYTVYRDVCAACHSLDRIAWRNLVGVSHTADQARALAEEIEYEDGPNDQGRPGKLSDYFPPPYPNEEAARAANGGALPPDLSLIIKARHGGADYVYSLLTGYVD-PPAG-VEIREGLNYNPYFPGGAIAMARLLYDGVVEYED-GTPATTSQMAKDVVTFLSWAAEPEHDERKKMGLQAVIILSSLKRFKWTNIKNRKFQY Botci1 YPWVHTFDHQALRRGFQVYQEVCASCHSLSRIPYRALVGVTHTVDEAKAMAEENEYDSEPNDEGRPGKLSDYLPSPYKNDEAARAANNGALPPDLSLMVKARHGGANYIFSLLTGYPDEPPAG-AKVPEGLNFNPYFPGTGIAMGRVLYNELVEYED-GTPASASQMAKDVVEFLNWSAEPEMDQRKKMGMKVLVIGSMLKRYKWSPIKTRKIVY Caeel LPWAHSFDIASVRRGYEVYKQVCAACHSMKFLHYRHFVDTIMTEEEAKAEAADALIND-VDDKGRPGMLTDKLPNPYPNKKAAAAANNGAAPPDLSLMALARHGGDDYVFSLLTGYLE-APAG-VKVDDGKAYNPYFPGGIISMPQQLFDEGIEYKD-GTPATMSQQAKDVSAFMHWAAEPFHDTRKKWALKIAALIPFVKRHIWSFTKSQKFLF Canalb1 YNWPHTFDHASIRRGFQVYREVCAACHSLDRIAWRNLVGVSHTTSEAKAMAEELEYDDEPDDEGRPGKLADYIPGPYENEQAARAANQGAYPPDLSLIVKARHGGSDYIFSLLTGYPDEPPAG-VVLPEGSNYNPYFPGGAIAMGRVLFDDLVEYED-GTPATTSQMAKDVSTFLNWASEPEHDDRKKWGLKALVVLSSLKRFKWTPIKNRKFRF Cangl YAWSHTFDHASIRRGYQVYREVCAACHSLDRVAWRTMVGVSHTNEEVREMAAEFEYDDEPDEQGRIGKLSDYIPGPYPNEQAARAANQGALPPDLSLIVKARHGAADYIFALLTGYPDDPPAG-VQLPPGTNYNPYFPGGAISMARVLFDDLVEYED-GTPATTSQMAKDVTTFLNWCAEPEHDERKKAGLKALLLLSSLKKFKWAAIKNRKFVF Capow YPWSHSFDHASVRRGFEVYKQVCSACHSLDKIAFRNLVGVTHTLDEAKALAADVDVEDGPDDSGRPGKLSDYMPRPYPNDQAARFANGGALPPDLSLVIKARHGREDYLFALLTGYKE-PPAG-IVLREGLHYNPYFAGGAIGMAQALYDEMIEYED-GTPASQSQMAKDVATFLAWAAEPEMNERKRMGMKAITLLTLAKRQRWSVLKTRKHVY Catan2 YPWNHSFDHASIRRGYQVYKEVCAACHSLDRIAYRNLVGVSHSLDEAKALAEEMEFQDGPNDVGRPGKLSDYHPRPYPNEEAARAANAGAYPPDLSLMVKARHGGEDYIFSLLMGYCD-PPAG-IEIREGLNYNPYFPGGAIGMARNIYDEVVEYED-GTPATAAQIAKDVTTFLAWAAEPEHDDRKRMGLKAMILLTAAKRFKWSLLKSRKIVY Cioin YPWQHTLDAASVRRGYEVYRQVCAACHSMEYLAFRNLVGVSHTEEEAKALAAQAQILDGPNELGRPGRLSDYFPKPYANDDEARAANNGALPPDLSFIVLGRHGEEDYIYSLLTGYYD-PPAG-VTIGEDQHYNAYFPGQAIGMAQALYNEIIEYED-GTPAVQSQLAKDVSTFLRWAAEPHHDTRKLSGFRVACFGLLFKKRIFSLVKSKKIAF CocheC53 YPWEHTFDHAALRRGFQVYREVCASCHSISRVPYRALVGKFMTVDEAKALAEENEYDTEPNDQGRPGKLSDYMPAPYKNDEAARAANNGALPPDLSLMVKARHGGCNYIFSLLTGYPEEPPAG-AVVQDGLNFNPYFPGTGIAMARVLYDDLVEYED-GTKASTSQMAKDVVEFLNWAAEPEMDDRKKMGWKVLAVTSVLKRYKWGPLKNRKILY Coere1 YPFPQTFDHASIRRGFQVFKEVCSACHSMDLVYWRNLVGVAYSEDEVRVMAEEFQYTDGPNDNGRPGKLTDPIPRPYANEEAARAANAGALPPDLSLITKARHGGVDYIYALLTGYCD-PPAG-VEIREGLNYNPYFPGGSIAMAQNIFDGVVEYED-GTPNTASQITKDVVTFLNWAAEPELDDRKKIGAKAILLFSILKRNRWQTLKTRKIAF Conco1 YPWVQTFDHASIRRGYQVYKEVCAACHSMNRIAFRNLIGVSHTEDEAKALAEEFEFTDGPNDVGRPGKLSDYFPNPYANEEQARAGNAGAYPPDLSLIVKARHGGPDYIFALLTGYVD-PPGG-VEVREGLNYNPYFPGGAIAMARVLYDGLVEYED-GTPATTSQMAKDVSNFLHWASEPEHDDRKRMGMKAVFILSLLKRFKWSGLKTRKIVY Conpu1 YPWPHTFDHSSIRRGFQVYREVCAACHSLDRIAWRNLVGVSHTVDEARTLAEDIEYEDGPDDNGRPGKLADYMPKPYPNEEAARAGNAGALPPDLSLIIKARHGGADYVFSLLTGYID-PPAG-VEIREGMNYNPYFPGGAIGMARLLFDGLVEYDD-GTPATTSQMAKDVVTFLNWAAEPEHDERKKLGLKAVILFSSLKKFKWSVIKNRKILY Copci YPWSHSFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTVDEARAMAEEVEYTDGPDSEGRPGKLADYMPAPYPNEEAARASNGGAYPPDLSLIVKARHGGADYLFSLLTGYID-PPAG-VEIREGMNYNPYFPGGAISMARVLFDGLVEYED-GTPATTSQMAKDVTTFLAWAAEPEHDERKKTGIKAVIIFSTLKRFKWNVIKNRKIVY Croqu1 YPWAHTFDHAAIRRGYQVYREVCSACHSLDRIAWRNLVGVSHTVDEVKGMAAEFEYEDGPNDEGRPGKLADYMPKPYPNEEAGRSANGGALPPDLSLIVKARHGGPDYIMALLTGYVD-PPAG-VEIREGLNYNPYFPGGAIAMARVLYDGVVEYPD-GTPATTSQMAKDVVSFLAWTAEPELDQRKKMGFQSVIILTTLKRFKWAGIKSRKLIY CryneH991 WPFEHTFNHSAIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTVDEVKAMAEEVEYEDGPNDEGRPGKLADYMPAPYPNEEAARAGNAGALPPDLSLIIKARHGGADYVYSLLTGYCD-PPAG-VKVAEGMNYNPYFPGGGIAMARVLFDGLVEYDD-GTPATTSQMAKDVVTFLSWAAEPEHDQRKKMGMQALIVLSSMKRFKWAYLKNRKIVY Crypa2 YPWVHTFDHQALRRGFQVYQEVCSSCHSLSRVPYRAMVGTILTVDEAKAMAEENEYDNEPNDEGRPGKLSDYLPAPYKNDEAARFANNGALPPDLSLIVKARHGGCNYIFSLLTGYPEEPPAG-ATVGAGLNFNPYFPGTGIAMARVLYDGLVEYED-GTPATTSQMAKDVVEFLNWAAEPEMDQRKKYGMQVLMVTSVLKKYKWAWIKTRKIVY Debha1 YGWSHTFDHASIRRGYQVYQEVCAACHSLERIAWRNLVGVSHTTTEAKAFAEDLEYDDEPDDEGRPGKLADYIPSPYENEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDDPPAG-VVLPEGSNYNPYFPGGAIAMARVLFDDLVEYED-GTPATTSQMAKDVTTFLNWASEPEHDDRKKWGLKALIIVSSLKKFKWQPIKNRKIRF Dekbr2 YEWSHSFDHASIRRGFQVYREVCSACHSLDRISWRNLVGVSHTASEAKAMAAEFEYDDEPDDQGRPGKLTDPIPGPYANEQAARAANGGALPPDLSLIIKARHGGCDYVFSLLTGYPEEPPAG-VQLAPGANYNPYFPGGSIAMARVLFDDLVEYED-GTPASTSQEAKDVVTFLNWCSEPEHDERKKMGVKALLIVGSLKKFKWTPIKHRKIVF Dicdi YPWEHSYDHAAIRRGHQVYTQVCSTCHSLNLISYRHLANVAYTPEELKAMAADTTVMDGPDSEGRKGQVTDFHPKPYPNSNAARFANNGALPPDLSLVIKARGAHEDYVFSLLTGYCE-PPAG-VRVVGGQYFNPYFPGTKIAMAPPLADGMVEYDD-GTDNSMSQMAKDVSTFLCWASEPEHDDRKKLGMKVLLGVSIIKRLKWSVIKTRKISF Dmel QLWNHALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPDDTGRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHD-APAG-VVLREGQYFNPYFPGGAISMAQVLYNEVIEYED-GTPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGILGFLKRHKWSSLKSRKIVF Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba YPWHFTFDHAALRRGFEVYKQVCASCHGLSRVAFRNLVGVTHTAAEAKMLAEEIEFQDGPDENGRPGKLSDYFPEPYANENAARAANNGAYPPDLSLMTKARHNGSDYLFALLMGYCE-PPGG-VEIRDGLHYNPYFPGGAIGMARQLFDDMIEYDD-GTPATSSQMAKDVTEFLSWAAEPEMTERKLMGLRAMVLMTFAKRHRWTVIKNRKVVY Fomme1 WPFYHTFDHASIRRGYQVYREVCASCHSLERIAWRNLVGVSHTVDEVKAMAEEVEYTDGPNDAGRPGKLSDYMPSPYPNEEAARASNAGALPPDLSLMIKARHGGADYVFSLLTGYVD-PPAG-VKLLDGLNYNPYFPGGAIAMARVLFDGLVEYED-GTPATTSQMAKDVVTFLSWASEPEHDERKKYGLKAVILFSALKRYKWAPIKSRKIIY Fusgr1 YPWVHTFDHQALRRGFQVYQEVCQSCHSLSRVPYRTLVGSILTVDEAKALAEENEYPGEPDEQGRPGKLADYMLPPYKNEEAARFANNGALPPDLSLIIKARHGGCDYIFSLLTGYPEEPPAG-VQVAPGMNFNPYFPGTGIAMARVLYEGLVEYED-GTPATTSQMAKDVVEFLNWAAEPEMDDRKRMGMKVLVVSASLKRYKWAWLKSRKIAY Galma1 YPWSHTFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTADETRAMAEEVEYTDGPDAEGRPGKLADYMPPPYPNEEAARASNAGALPPDLSLIVKARHGGADYIFSLLTGYID-PPAG-VEIREGMNYNPYFPGGAISMARVLFDGLVEFED-GTPATTSQMAKDVVTFLNWAAEPEHDERKKYGIKAVVIFSVLKRFKWGPIKNRKIFY Ganpr1 WGFESTYDHQSIRRGYQVYKEVCAACHSLERIAFRNLIGVSHTEAEAKAIAAEFEYTDGPNDTGRPGKLSDYMPKPYPNEEASRAANGGAYPPDLSLITKARHSGKDYVFSLITGYCE-PPAG-VTIREGLYYNPYFPGGAIAMAPPISDGHVDYED-GTVNHKSQIAKDVVEFLAWAAEPEHDERKRMGWKFLMVAGTMKRFKWSYIKSRKVVY Gloin1 YPWPHTFDHASIRRGYQVYREVCSTCHSLEYISWRNLVGVSHTEDEVRAMAEEFEYKDGPDDNGRPGKLSDRFPRPYPNEEASRAANGGALPPDLSLVVKAREGGANYIFSLLTGYYD-PPAG-VEIREGLNYNPYFPGGAISMARLLFDGLVEYDD-GTPATTSQMAKDVTTFLSWAAEPEHDDRKKMGIKAIIMLSAMKRNRWVSLKSRKIAY Hisca1 YPWEHTFDHQALRRGFQVYREVCMACHSLTRVPWRAFVGTIHTVDEMKAMAEEYEYDTEPNDQGRPGKLSDYIPPPYKNDEAARAANNSALPPDLSLIVKARHGGCDYIFNLLTGYPDEPPAG-ATVQEGLNFNPYFPGTGIAMARVLFDGLVEYED-GTPATTSQMAKDVTEFLNWAAEPEMDERKKMGLKTLAITAMLKRYKWAPIKSRKIVY Klula1 YGWSHTFDHSSIRRGYQVYREVCAACHSLDRVAWRTMVGVSHTNAEVRAMAEEFEYDDEPDDQGRPGKLADYVPGPYPNEQAARAANQGALPPDLSLIVKARHGGPDYIFALLTGYPEEPPAG-VVLPPGANYNPYFPGGSIAMGRVLFDDLVEYED-GTPATTSQMAKDVTTFLHWCSEPEHDERKRLGLKAMIVLSSLKKFKWASIKSRKIVF Lacbi2 YPWSHTFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTADETRAMAEEVEYTDGPNAEGRPGKLADYMPAPYPNEEAARAGNAGALPPDLSLIVKARHGGADYVFSLLTGYID-APAG-VEIREGMNYNPFFPGGAISMARVLFDGLVEYDD-GTPATTSQMAKDVVTFLSWAAEPEHDERKKYGIKAVIILSACKRFKWTVIKNRKIFY Lenti61 YPWSHSFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTVDEVKAMAEEVEYEDGPNDQGRPGKLSDYLPPPYPNEEAARASNQGALPPDLSLIVKARHGGADYIFSLLTGYRD-PPAG-FEIREGMNYNPYFPGNAISMARVLFDGLVEYDD-GTPATTSQMAKDVVTFLNWAAEPEHDERKKAGLKAVILFSALKRHKWTVIKTRKIQY Malgl1 YPWEHTFDHAAIRRGFQVYQEVCSTCHSLERIAWRNLVGVSHTVDEVKAMAQDVEYEDGPNDNGRPGKLADYMPSPYPNEEAARAGNAGALPPDLSLIVKARHGGADYIFSLLTGYCD-PPAG-VTVQEGLNYNPFFPGTQIAMARVLFDDLVEYED-GTPATTSQMAKDVVTFLHFAAEPEHDQRKRAGFKALILLSSLKRFKWAPIMTRKIVY Mellp23 YPWAHTFDHAAIRRGYQVYREVCSACHSLDRIAWRNLVGVSHTVDEVKAMAGEVEYEDGPDDEGRPGKLSDYMPKPYPNEEAARSANAGALPPDLSLMVKARHGGADYVMALLTGYVD-PPAG-VQIREGLNYNPYFPGGAIGMARVLYDGVVEYPD-GTPATTSQLAKDVVSFLAWTAEPELDQRKKMGLQSVIILATLKRFKWAGIKSRKLVY Mnele MHWEHSYDHKALRRGFQVYKEVCQACHSMQYFYWRLHVDVTHTKEEIKEIAAEYMY-PGVDDDGRPGDIQDIMPAPYENEIKARLANNGAEPPDLTLINIAREGNEDYLFSLLTGYEE-VPAGQAEPAEGQAYNPYFHGYYIGMAQQLYNESVDYED-GTIPYQSQIAKDVIQYLSWTSHPWMDESIMYGMKAISSAALLMRTRRNGFRSRQIHF Monbr YPWEHTFDHASIRRGHQVYQQVCSACHSMELIAYRNLVGVCYNEDEAKELAAEQMFEDGPDDAGRPGKLADYFPKPFPNEEAARAANGGAYPPDLSLIVKARHGREDYIFSILTGYCD-APAG-VELRDGLYFNPYFSGQAIGMAPPLYNEQIEFED-GTPASVSQMAKDVVTFLTWAAEPEHDDRKRMGMKSIVLLSFVKRHKWTVLKNRVIQY Morel2 YPWDHTFDHAAIRRGYQVYKEVCAACHSLDRIAWRNLIGVSHTEAEVKAMAEEFEYTDGPNDVGRPGKPSDYMPKPYANEEQARAGNAGAYPPDLSLMIKARHGGADYVFSLLTGYQD-PPAG-VEIREGLNFNPYFPGGAIGMARVLYDGLVEYED-GTPATTSQMAKDVTIFLSWAAEPEMDERKKMGMKALTMLAILKRHKWAGLKTRKILY Mucci2 HPWPHTFDHASIRRGYQVYREVCSACHSLDRIAWRNLIDVSHSEDEVKAMAEEFEYQDGPDDNGRPGKPADYMPKPYPNDEAARAGNAGALPPDLSLITKARHGGEDYVFALLTGYVD-APGG-VEVREGLNYNPYFPGGAIAMAQTLFDGVVEYED-GTPATASQMAKDVCTFLAWAAEPEHDDRKKMGMKATIITAGLKKFKWAPLKTRKIVY Mydma HRWSHSLDHASIRRGYQVYKQVCVACHSMDQIAFRNLVGVSHTEEEVIELASQVQVTDGPNEKGRPGKLFDYFPKPYRNEEEARAANNGAYPPDLSWIVPARHGCEDYIFALLTGYREEPPAG-VKLQEGMSYNVYFPGQAIAMPQQLYPGVMEYDD-GTPATVSQMAKDVSTFLKWASEPEHDTKKRMGMKALVICGAMKRHKWSVLKSRKLVY Neucr2 YPWVHTFDHQALRRGFQVYREVCASCHSLSRVPYRALVGTILTVDEAKALAEENEYDTEPNDQGRPGKLSDYLPDPYKNDEAARFANNGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAG-ASVGAGLNFNPYFPGTGIAMARVLYDGLVDYED-GTPASTSQMAKDVVEFLNWAAEPEMDDRKRMGMKVLVVTSVLKRYKWAWLKSRKIVY Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YPWVHTFDHAALRRGFQVYREVCASCHSLSRVPWRSMVGTMHTVDEMKAFAEEHEYDTEPNNEGRPGKLSDYIPAPYPNEEAARAANGGALPPDLSLITKGRHGGCNYIFSLLTGYPDEPPAG-AAVAEGMNFNPYFPGTGIAMARVLFDGVVEYED-GTPATTSQMAKDVVEFLNWSAEPEMDERKKMGVKAVALLTGLKRYKWAPLKTRKIVY Phybl2 HPWYHTYDHAAIRRGYQVYKEVCSACHSLDRIAWRNLIDVSHTEDEVKAMSEQEEYQDGPDDNGRPGKPSDYMPRPYPNDEAARAANAGALPPDLSLMTKARHGGADYVFALLTGYVD-APGG-VEVREGLNYNPYFPGGAIAMARVLFDGVVEYED-GTPATTSQMARDVSTFLAWAAEPEHDERKKMGMKATVILTGLKRFKWAPIKSRKIVY Picst3 YGWSHAFDHASIRRGYQVYREVCAACHSLDRIAWRNLVAVSHTSSEAKAFAEELEYDDEPDDEGRPGKLADYLPAPYANEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPEEPPAG-VVLPPGANYNPYFPGGSIAMGRVLFDGLVEYED-GTPATTSQMAKDVVTFLNWASEPEHDDRKRWGLKAIVIVSSLKRFKWQPIKNRKIRF Plicr1 YPWPHTFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHSVDEVKAMAEEVEYQDGPNDEGRPGKLADYMPPPYPNEEAARAGNGGALPPDLSLIIKARHGGPDYIFSLLTGYVD-PPAG-VEIREGMNYNPYFPGGAISMARVLFDGLVEYDD-GTPATTSQMAKDVVTFLHWAAEPEHDERKKIGLKAVILFSALKRFKWAVIKNRKIVY Polpo FPWNHSFDHASIRRGHQVYTQVCSTCHSLDMISYRHLIDVAYTADEMKAYTAELTVMDGPDSEGRKGAITDYHPKPYENQNAARFSNNGALPPDMSLVVKARGRHEDYVFSLLTTYVE-PPSG-VKITQGQYFNPYFPGTKIAMAPPLSEGQVEFDD-GTEASVSQMAKDVSTFLAWASEPEHDDRKKLGIKIILGLSLIAFCFLTTITTAKT-- Pucgr2 YAWPHTFDHAAIRRGYQVYREVCSACHSLDRIAWRNLVGVSHTVDEVKAMATEVEYEDGPDDEGRPGKLADYMPRPYPNDEAARSANAGALPPDLSLIVKARHGAADYVMALLTGYVD-PPAG-VEIRDGLNYNPYFPGGAIGMARVLYDGVVDYPD-GTPATTSQMAKDVVTFLNWAAEPELDQRKKMGFQTVIVLTTLKRLKWAGIKSRKIVY Punst1 YPWSHSFDHASIRRGYQVYREVCSSCHSLDRIAWRNLVGVSHTVDEVKAMAEEVEYTDGPDDQGRPGKLSDYMPAPYPNEEAARAANGNALPPDLSLMAKARHGGIDYIFSLLTGYQD-PPAG-VELPENMNYNPYFPNGAIAMARVLFDGLVEYED-GTPATTSQMAKDVCTFLNWAAEPEHDERKKSGLKAVILFSALKRFRWATIKTRKISY Rhior3 YPWPHTFDHAAIRRGYQVYREVCSACHSLDRIAWRNLVGVSHTEAEAKAMAEEFEYQDGPDDKGRPGKLSDYMPQPYANEEAARAANAGALPPDLSLITKARHGGEDYVFSLLTGYVD-APGG-IEVREGLNYNPYFPGGAIAMARVLFDGVVEYED-GTPATTSQMAKDVSTFLAWAAEPEHDDRKKMGMKAVIILTGLKRFKWAPIKSRKIVY Rhoto1 YPWAHTFDHSAIRRGYQVYREVCSTCHSLDRVAWRNLVGVSHTVTEAKTMAEEVEYEDGPDDQGRPGKLSDYFPRPYDNDEAARSGNAGALPPDLSLITKARHGGADYVYALLTGYVD-PPPG-VEIREGLNYNPYFPGGAIGMARVLYDGLVEYED-GTPATTSQMAKDVVTFLAWASEPELDQRKKMGMQATIILSGLKKFKWAGIKSRKLVY Rozal11 YPWDHSFDHAA--RGFQVYQQVCAACHSMRKITWRNLIDVTHTEEELKEMASEAMYLDGPNEKGRPGKV-NKLPSPYPNAEAARYANGGALPPDLSNISIAREGEADYIFSLLTGYSD-PPAG-VAAKPGLHYNKYFQGGAIAMARNIYDDVVEYED----------AKDVTTFLAWASVPDTDDRKLAGMKALIVVGGLLRHKWSVLKSRKLIY Sacce1 YAWSHTFDHASIRRGYQVYREVCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDEQGRPGKLSDYIPGPYPNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAG-VALPPGSNYNPYFPGGSIAMARVLFDDMVEYED-GTPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSSLKKFKWAGIKTRKFVF Salro YPWSHSFDHASIRRGHQVYQQVCAACHSLERIAYRNLVGACYNETEAKELASETMVEDGPDDNGRPGKLADYFPSPFPNEEAARAANNGAYPPDLSLIIKARHGREDYVFSLLTGYCD-APAG-VEIREGLYYNPYFPGQAIAMAPPLYDDQIEYDD-GTPATLSQMAKDVVTFLTWCAEPEHDDRKRFGMKAMILLSLVKRHKWSTLKSRVVAY Schco3 YPWSHSFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTADEARAMAEEIEYQDGPDDNGRPGKLSDYMPAPYPNEEAARASNAGALPPDLSLIVKARHGGADYIFSLLTGYID-PPAG-VEIREGMNYNPFFPGGAIGMARVLFDGLVEYDD-GTPATTSQMAKDVVTFLNWAAEPEHDERKKVGIKAVILFSTLKRFKWTPIKNRKIVY Schpo1 HDWPQGFDHASLRRGFQVYREVCSACHSLNLIAWRHLVGVTHTADEAKQMASEVEYEDGPDDEGRPGKLSDFLPPPYPNVEAARASNNGAAPPDLSCVVRGRHGGQDYIYSLLTGYTE-PPAG-VEVPDGMNFNPFFPGTQIAMARPLFDDAVEFED-GTPATTAQAAKDVVNFLHWASEPELDIRKKMGFQVITVLTILKRFKWTPIKNRKIFY Sorma YPWVHTFDHQALRRGFQVYREVCASCHSLSRVPYRSLVGTILTVDEAKALAEENEYDTEPNDQGRPGKLSDYLPDPYKNDEAARFANNGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAG-ATVGAGLNFNPYFPGTGIAMARVLYDGLVDYED-GTPASTSQMAKDVVEFLNWAAEPEMDDRKRMGMKVLVVTSVLKRYKWAWLKSRKIVY Sphar YPWSHSLDHASMRRGFQVYQEVCSACHSLRRICYRNLVGNTHTVNEAKELAEDIEVVDGPDDEGRPGKLADHMPSPYPNDEAARFANGGALPPDLSLIVKARHGREDYLFALLTGFHE-PPAG-VNIREGLHFNPYFPGLAIGMARPIYDGMVEYED-GTPATTSQMAKDVITFLTWCAEPEHDERKRMGMKCMSILGMAKRNKWIVIKSRKISY Spipu1 YPWDHSYDHASIRRGFQVYKEVCSACHSMDYIYYRNLVGVSHTEAEAKALAAEYEYEDGPDDSGRPGKLTDAMPKPYPNEEAARAANGGAYPPDLSCIVRARHGEEDYIFALLLGYCD-PPAG-VNIREGLHYNPYFPGGAIAMARSIFDEVVDYED-GTPNNASQLAKDVTTFLSWASYPEHDERKKMGLKTLAISAMLKRFKWSYVKSKKIVY Sporo1 YPWAHTFDHASIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTVNEAKTMAEEVEYEDGPDSEGRPGKLSDYMPAPYANEEAARAGNAGALPPDLSLITKARHGGADYVYALITGYVD-PPAG-VEIREGLNYNPYFPGGAIGMARVLYDGLVEYED-GTPATTSQMAKDVVTFLAWSSEPELDDRKKMGMQATIILTSLKKFKWGPLKARKIVY Stehi1 YPWPHSFDHASIRRGYAVYREVCAACHSLDRIAWRNLVGVSHTVDEVKAMAEEVEYTDGPNDQGRPGKLSDYMPPPYPNEEAARASNAGALPPDLSLIVKARHGAADYIFSLLTGYVD-PPAG-VEIREGMNYNPYFPGGAISMPRVIFDGLVEYED-GTPSTTSQMAKDVTTFLNWAAEPEHDDRKKIGIKAVILFSTLKRFKWTVIKNRKLVY Tapde11 YPWPQTYDHQSLRRGYQVYREVCSACHSLDRIAWRNLVGVTHTVDEAKGMCEEVEYEDGPDDNGRPGKLSDYMPRPYPNDEAARAGNAGALPPDLSLITKARHGGSDYIFSLITGYVD-PPAG-LHLAEGMNFNPYFPGTGIAMARVLYDGLVEYED-GTPATTSQMAKDVVSFLQWSAEPELDDRKKMGFQAVCILSILKRFKWAPIKTRKLQY Thetr YPWDHTYDHASIRRGHQVFKEVCATCHSLDRLAYRNLVGVAYTEEEAKALAAEIEVEDGPNDEGRPGKLSDYFPRPYANEEIARKANNGALPPDLSLIVKARHDGANYVFALLTGYPEDPPAG-VELRDGLHYNPYFPGGAIGMAKALEDGLVEFED-GTPGTASQAAKDVTMFLAWVAEPELEERRLAGLTALVFLGLVKRLTWAVVKSAQVVR Treme1 YPFEHTFNHSAIRRGYQVYREVCAACHSLDRIAWRNLVGVSHTVDEVKAMAEEVEYTDGPNDEGRPGKLADYMPPPYPNEEAARAGNGGGLPPDLSLIIKARHGGADYVYSLLTGYVD-PPAG-VNVAEGMNYNPYFPGGGIAMARVLYDGLVEYDD-GTPATSSQMAKDVVTFLSWAAEPEHDERKKMGLQAVIILSTMKRFKWSVVKNRKLYY Trire2 YPWVHSFDHQALRRGFQVYREVCASCHSLSRVPYRALVGTILTVDEAKALAEENEYPDEPDEQGRPGKLADYIPPPYKNDEAARFANNGALPPDLSLIVKARHGGCDYIFSLLTGYPEEPPAG-VKLAPGMNFNPYFPGTGIGMARVLYDGLVEYED-GTPASTSQMAKDVVEFLNWAAEPEMDDRKKMGMKVLVATTALKRYKWAWLKSRKLVY Umbra1 HPWYHTFDHAAIRRGYQVYREVCSACHSLDRIAWRNLIDVSHSEDEVKALAEEVEYEDGPDDEGRPGKPSDYMPKPYPNEEAARAGNAGALPPDLSLIVKARHGGADYVFALLTGYVD-APAG-VEVREGLNYNPYFPGGAIAMARVLFDGLVEYED-GTPATTSQMARDVTTFLAWAAEPEHDDRKKMGMKATIILSTLKRFKWAPLKTRKIVY Ustma22 YPWSHTFDHASIRRGYQVYREVCSSCHSLDRIAWRNLVGQSHTVDEAKAMAEEVEYEDGPDDEGRPGKLADYMPRPYANDEAARAANAGALPPDLSLMVKARHGGADYIFALLTGYTD-PPAG-VKVQDGLNYNSYFPGTQIAMARVLYDGLVDYED-GTPATTSQMAKDVVTFLHFCAEPEHDTRKKMGMQAVIILSSLKRFKWAGVKNRKLVY Walse1 FPWSHSFDHNSIRRGYQVYREVCSSCHSLDRIAWRNLVAVSHTSDEARAMAEEVEYTDGPNDQGRPGKLADYMPAPYPNEEASRAANGGALPPDLSLMVKARHGGADYIMALLTGYQD-PPAG-ISVAEGMNFNPYFPGGQIAMGRVLFDGLVEYDD-GTPATTTQMAKDVSTFLSWASEPEHDDRKKMGMQAVIVLSAMKRLKWSPIKTRKLVY Zygro1 FSWPHTFDHAAIRRGYQVYREVCAACHSLDRIAWRTLIGVSHTNQEVRDMSAEFEYDDEPDEQGRPGKLADYIPGPYPNEQAARSANQGALPPDLSLIVKARHGGADYIFSLLTGYPEEPPAG-VVLPPGSNYNPYFPGGAIAMGRVLFDDLVEYED-GTPATTSQMAKDVTTFLNWCSEPEHDERKRLGLKAILVVSSLKKFKWAAIKNRKFVF [Cluster1693.fasta_al_trimmed; alignment length = 241] Allma1 DYFDKLAHLLESHKSIFVISVDNVGSNQMHQVRRKLRGILMGKNTTVRRALRYEKLLPHVRGNIGFVFTDLKTVRDAIVEDRVRAPAKAGAVAPVDVTVPGGNTGMEPGKTSFFQALGIPTKITKGMVEITTDYPLIKAGSKVGPSEATLLNMMNISPFTYGVNVTQVFNEGNTFVLDIEESELLGHLLAGIRAIAAVSLAIGVPTVASVPHSLINAYKNVLTEISFEEEDDDM-GF-GLF Ashgo11 EYFAKLREYLEEYKSVFVVGVDNVSSQQMHEVRKALRGVLMGKNTMVRRAIRYEKLLPFVKGNVGFVFTPLTDIKEVIVANKVAAPARAGAVAPEDIWVLAVNTGMEPGKTSFFQALGVPTKIARGTIEITSDVKVVEAGNRVGASEASLLNLLNISPFTYGLTVVQVYDNGQVFILDITDEELVSHFVTAVNTIASISLAIGYPTLPSVGHTLINNYKDLLANYVYESEDDDM-GF-GLF Aspfu1 AYFDKLKSLLDEYKTVFIVGVDNVSSQQMHEIRLALRGVLMGKNTMVRRAIKYERLLPHVKGNVGFIFTDLKDVKTKILANRVAAPARAGAIAPADVWVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGAKVGPSEATLLNMLNISPFTYGMTITQVYDNGQCFVLDIEESQLLDAFSSAIKTITTVSLALNYPTLPSVMHSLINGYKKVLTDYSWESDE-DM-GF-GLF Aurde31 AYFVKLKELIAEYPSIFLVNVDNVGSNQMHQIRVSLRGVLMGKNTMVRRALRLERLLPHVKGNIGFVFTDLKEVRELIISNKVAAPARAGAFAPKDVIIPAGNTMMEPGKTSFFQALGIPTKIARGTIEIVSDVKVVSASTRVGQSEATLLNMLNISPFTYGMSVVQIFSDGNIFVLDIDDDELIGRFLSGIKTIAAISLALNYPTLASVAHSLVNAYKNLLTDYSFEESDDDM-GF-GLF Batde5 NYFTKLNELLTDYSTVFIVNVDNVGSNQMHQIRKSLRGVLMGKNTMVRRALRFEKLLALVRGNIGFVFTDLKDIRDDILSNRVQAPAKAGAVAPVNVTVPAGNTGMEPGKTSFFQAIGIATKIARGTIEIISDVEIITAGNRVGASEAQLLNMLNISPFTYGLTITSIYENGTVFILDITDDVLIGHLLTGITTVTALSLGLGFPTVASVPHLLVNGYKNVLEEYTFEESDGDM-GF-GLF Botbo1 AYFVKLKQLVEVYKSIFLVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFERLLPYVRGNIGFVFTDLKEVRETLLANKVAAPARAGAFAPKDVTVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIISDVRVVTAGTRVGTSEATLLNMLNISPFTYGMSVVQIFDSGNVFVLDVDEQELINRFLSGIKTVAAISLALNYPTVVSVVHSLVNAYKNLITEISFEESDDDM-GF-GLF Botci1 GYFDKLKGLLEEYKSIFIVTVDNVSSQQMHEIRGSLRGVLMGKSTMVRRAVKYERLLPFVKGNVGFVFTDLKTIRDKILDNKVAAPARAGAVAPADVYVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITADLKLVEAGSKVGASEATLLNMLNISPFTYGMGISQVYDAGNTFVLDIEEAQLLKAFSSAITTIAAISLAANFPTLPSVMHSVVNSYKKVLTDYSWAEESADE-GFGGMF Caeel NYFTKLVELFEEYPKCLLVGVDNVGSKQMQEIRQAMRGILMGKNTMIRKALRLEKLLPHIVENVGFVFTDLGEIRSKLLENRKGAPAKAGAIAPCDVKLPPQNTGMGPEKTSFFQALQIPTKIARGTIEILNDVHLIKEGDKVGASESALLNMLGVTPFSYGLVVRQVYDDGTLYVLDMTTEELRKRFLSGVRNVASVSLAVNYPTLASVAHSLANGLQNMLTDVSFEESDDDM-GF-GLF Canalb1 QYFSKLRELLEEYKSIFVVGVDNVSSQQMHEIRKALRGVLMGKNTMVRRAIRFEKLLPFIKGNVGFIFTDLKSIRDIVVSNVVAAPARAGAVAPKDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVEQDAKVGPSEATLLNMLNISPFTYGMSVVQVYDNGQVFILDITDDELISHFVSAINTIASISLAAGYPTLPSVGHSIINNYKNVLTDYTYEESDDDM-GF-GLF Cangl EYFAKLREYLEEYKSIFVVGVDNVSSQQMHQVRKALRGVLMGKNTMVRRAIRYEKLLPFIKGNVGFIFTSLKDIKEVIVANKVAAPARSGAVAPEDIWVKAMNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVEAGNRVGPSEASLLNLLNISPFTYGLTVVQVYDQGQVFILDITDEELVSHFVSAVTTVAAISLAAGYPTLPSVGHTLINNYKNLLSSYHYES-DDDM-GF-GLF Capow DYFTKLVQLLQEYPRLFIVGVDNVGSNQMQQIRMSLRGILMGKNTMIRKAIRVEKLLPFIRENVGFVFTDLSQVRTIITANRVAAPAKAGALAPVDVFVPAGNTGLGPEKTSFFQALSIPTKIARGTIEIVSDVHLIKSGDKVDASAAALLNMLAISPFSYGLVIRNVYDNGAVFVLDITQDDLLSKFTLGVRNVAAVSLAIDFPTVASVPHSIVNAYKNVLIDYTFESEEGDM-GF-GLF Catan2 ----------------------------MHNVRRKLRSVLMGKNTMVRRALRYEKILPHIKGNVGFIFTDLKTMRDQIIEDRVRAPAKAGALAPLDVTVPAGNTGMEPGKTSFFQALGIPTKITKGTVEITSDFPLIKAGSKVGPSEAALLNMMNISPFTYGLSVVQVYNDGNAFVLDIDDETLLNHLVEGIRAVAAVSLAIGVPTAASVPHSLINGYKNVLTDLSFEEEDVD---F-DLF Cioin NYFVKLINLLDEYPKCFIVGADNVSSKQMQQIRTSLREVLMGKNTMMRKAIKLERLLPHIRGNVGLVFTDLIETRDLLLANKVAAPARAGAVAPNDVIVPAQNTGLGPEKTSFFQALAIPTKISRGTIEIISDVHLIKPGDKVGASDATLLSMLKIFPFTYGLEIEQVYDSGSVFVLDITDDDIRRKFTNAVRNVASVCLAIGYPTVASAPHSIINGFKNILTEITFEESDDDM-GF-GLF CocheC53 AYFEKLDVLLKEYKSIFIVTVDNVSSQQMHEIRQSLRGVLMGKNTMVRRALKYERLLPHVKGNVGFVFTDLKQIRDKILSNRVAAPARAGAVAPGDVYIPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLIEAGNKVGASEATLLNLLNISPFTYGMGIYQIYDNGQTFVLDISEEQLLKTFSTAITTIATISLALNYPTLPSVMHSVVNSYKKVLTDYEWESEDEDM-GF-GLF Coere1 AYFAKLEHLLSTYQTIFIVNVDNVSSQQMHIVRQSLRGILMGKNTMVRRALRYEALLPFVKGNIGFVFTDMKETREKIISNRVAAPARPNAIAPADVFVPAGNTGMEPGQTSFFQALGIPTKIARGTIEITNDVHLVKIGEKVGASEATLLNKLGISPFTYGLVVTQIYDNGATFVLDITEDDLVDRLMEGITTIASISLAVDYLALPAIPHLTINVFKDILTDYTIEESDDDM-GF-GLF Conco1 DYFNKLRDLLENYKSAFIVTVDNVGSNQLHQIRVSLRGILMGKNTMIRRAFKIEKMLPFIRGNVGFVFTNLKDIRDKITANRVAAPAKAGAIAPLNVTIPAGNTGMEPGKTNFFQALGVPTKITKGSIEIINEVHLIKKDTRVGPSEATLLNMLKISPFTYGMNVLQVYDEGALFVLDVEESTLIERFLSGASSVAAISLALDYPTIASVPHSLINVYKNVLTDYTFDESDDDM-GL-DLF Conpu1 IYFVKLKELITQYPSIFIVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFERLLPHVRGNVGFVFTELKDVRDIITANKVAAPARAGAFAPKDVFVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVQVVVAGTRVGSSEATLLNMLNISPFTYGMTVVQIFDNGNSFVLDIEEDELLGRFLSGIKTIAAISLAINYPTIVSVTHTLVNSYKNLITDYMFEESDDDM-GF-GLF Copci LYFEKLKELLATYPSIFIVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRYERLLPHVKGNVGFVFTDLKEVREIIVANKVAAPARAGALAPVDVSVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVKVVFAGTRVGPSEAALLNMLNISPFTYGMTVIQIYDRGNTFVLDVEESELVERFLTGIKTIAAISLAINYPTIASITHSLVNAYKNLLTDYTFEESDEDM-GF-DLF Croqu1 AYFTKLQDLMAEFPSAFIVNVDNVGSNQMHQIRQALRGVLMGKNTMVRRAIRYERILPLIKGNIGFVFTDLKDVRDTITANKVAAPAKAGAFAPLDVTVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDIKIVTAGNRVGASEATLLNLLKISPFTFGMTVLSIYDKGNIFVLDIDEQTLINQFLSGAKTIAAISLATNYPTIASVTHSLVNGYKNLITDFVFESEDEDL-GL-DLF CryneH991 LYFEKLRALIEKYPSIFVVNIDNVSSQQCHMIRQALRGVLMGKNTMVRRAIRFEKLMPFVKGNIGFVFTDLKDVREIIIANKVAAPARAGAFAPNDVYVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVQVVAAGSKVGPSEATLLNMLNISPFTYGMTVVQVYDNGAVFILDIEEKTLIDQFVSGIKTVAAISLATGIPTIASVMHSLVNSYKNILTDYEFEESDDDM-GF-GLF Crypa2 GYFDKLKGLLEEYQSVFIVGVDNVSSQQMHEIRQALRGVLMGKNTMVRRALKYERLLPYVKGNVGFVFTDLKAIRDKILDNKVAAPARAGAVAPDDVWVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGSKVGPSEATLLNMLNISPFTYGLAVEQVYDQGNCFVLDISEDQLLKSFSSAVTTIATISLALNYPTLPSIMHSLVNGYKKVLTEISWEEDD-DM-GF-GLF Debha1 QYFSKLRELLEEYKSIFIVGVDNVSSQQMHEIRKALRGVLMGKNTMVRRALRYEKLMPFVRGNVGFIFTDLKTIRDTIVSNVVAAPAKAGAVAPKDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVRVVETNSKVGPSEATLLNMLDISPFTYGMSVVQVYDNGQIFILDITDDELVGHFVSAINTIASISLAVGYPTLPSVGHSVVNHYKNVLTDYTFEESDGDM-GM-GLF Dekbr2 EYFLRLKQYVQDFKSVFVVGIDNVSSQQMHEVRKALRGVVMGKNTMIRRALRYEKLMPYIRGNVGFIFTDLKHIKEVVLANQVAAPARPGAIAPCDVYVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITSDVKILDKDQKVGPSEAQLLNMLKISPFTFAMSVIEVYDDGDIFLLDITDDELVADFTEAVSNITKISLASGYPTVSAVSTHVINAYQDIVSDYTF-----------GIF Dicdi VFIEKATKLFTTYDKMIVAEADFVGSSQLQKIRKSIRGVLMGKKTMIRKVIRLDALNTYLKQNTCIIFCNIAEVKRVINTQRVGAPAKAGVFAPNDVIIPAGPTGMEPTQTSFLQDLKIATKINRGQIDIVNEVHIIKTGQKVGASEATLLQKLNIKPFTYGLEPKIIYDAGACY---ISEEDLINKFKQGIFNIAAISLEIGYPTVASIPHSVMNAFKNLLTSYTFEESDDDM-GM-GLF Dmel QYFIKVVELFDEFPKCFIVGADNVGSKQMQNIRTSLRGVLMGKNTMMRKAIRLEKLLPHIKGNVGFVFTDLAEVRDKLLESKVRAPARPGAIAPLHVIIPAQNTGLGPEKTSFFQALSIPTKISKGTIEIINDVPILKPGDKVGASEATLLNMLNISPFSYGLIVNQVYDSGSIFILDIKPEDLRAKFQQGVANLAAVCLSVGYPTIASAPHSIANGFKNLLTEVEFEEEDDDM-GF-GLF Enthi AYLVKMKKLLEEYKQVVVVKCDNVGSSQFQTIRKELRGFVMGKNTLIRKAIKLEELLPHIKGNVGFIFTDLYQLKAKLTELKAPSPAKAGVIAPNDVIVPAGDTGLDPTQTNFVQALNIASKITKGQIEITSETLLIKEGEKVGVSQAVLLQKLKINPFKYGAVIDVVYDNGIVYALDLTESDIVKKFQEGVQAATAISLAANLPTEAACPHLMLNAFQALLSGVVFEEEEEDFGGFGDLF Falba IYFEKLHSLLVNYPKIFIVEADNVGSQQMHLTRQSLRGILMGKNTMVRKIIRLERLLPHINGNIGFVFTDLKDVRAKIMAQRVAAPARAGAIAQQDICLEPHNTGQGPEKTSFFQALRINTKITRGTIEILNKVTLIAEGEKVGPSEAALLNMLGMSPFTYGLTVRTIYDSGAMFILDIDEDVLLGHIRAGIANVAAVSLAVGVPTKASVTHSMVNGFKNLLTDLSFDESDDDM-GF-GLF Fomme1 EYFVKLRELLIKYPSIFIVNVDNVGSNQMHQIRVSLRGVLMGKNTMVRRALRFERLLPYIKGNIGFVFTDLKDIREVIVANKVAAPARAGAFAPMDVVVPAGNTGMEPGKTSFFQALNIPTKIARGTIEIVSDIKVVTAGSRVGPSEATLLNMLNISPFTYGMTVVQIYDQGNVFVLDVDEKELLDRFLSGVKTIAAISLALNYPTIVSVTHTLVNAYKNLITDYTFEESDDDM-GF-GLF Fusgr1 LYFDKLKGLLEKYTSIFIVEIDNVSSQQMHEIRHALRNVLMGKNTMVRRALKYERLLPHVKGNVGFVFTDLKEVRDVILANKVAAPARAGALAPADVWVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGSKVGPSEATLLNMLNISPFTYGMGISQVYDQGQTFVLDVGEEQLLKTLSQAIATIATISLALNFPTLPSVLHSLVNSYKKVLTEVSWEEED-DE-GFGGLF Galma1 IYFEKLKELLAKYPSIFLVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFERLLPYVKGNIGFVFTDLKDVREIIVANKVAAPARAGAFAPKDVTVPACNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVKVVTAGTRVGSSEATLLNMLNISPFTYGMTVVQIFDQGNIFVLDIDEQELVDRFLSGIKTIAAISLALNYPTIVSVTHTLVNAYKNLLTEYTFEESDDDM-GF-GLF Ganpr1 LYFEKLEHLLTDYPTIFIVNVDNVGSNQMHQIRKQLRGILMGKNTMIRKKLRLERLMPVVRGNVGLVFTDLKAIRGKITENRVRAPAKAGAIAPVAVSIPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVNDVPIIKPGQKVGASEATLLNMLNISPFTYGLSIQQVYDQGDVFLLDIDVSKLAEHFFTGAGVVTKLSLGLGYPTMASIPHLLVSGYKNILTGYTFEDEDEEM-GF-GLF Gloin1 EYFNKLKTLLEEYPSIFIVNVDNVGSNQMHQIRHTLRRVLMGKNTMVRRALKYEKLLPHVKGNVGFVFTDLKETRDVILSNRVKAPAKAGAIAPIDVFVPAGNTGMEPGKTSFFQALGVPTKIARGTIEIINQVHLVKKETKVGASEATLLNMLNISPFTYGMTVTQIFDNGTTFVLDIEEDTLISHLLTGIRRIAALSLQLHYPTLASIPHSLINGFKNLLTEYTFEETDEDM-GL-DLF Hisca1 AYFDKLKALLDEYRSVLIVTVDNVSSQQMHEIRLSLRGVLMGKNTMVRRAIKYERLLPHVRGNIGFIFTDLKEVRQKVLSNRIAAPARAGAIAPLDVYVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGSKVGASEATLLNMLNISPFTYGMTVAQIYDDGQTFVLDVGEEQLLSSLQSAIRTITTISLATNFPTLPSVMHSVVNSYKNMITEYGWESED-EG-GFGDLF Klula1 EYFAKLREYLEEYKSVFVVGVDNVSSQQMHEVRKNLRGVLMGKNTMVRRAVRYEKLLPFVKGNVGFIFTSLQDIKEVIIANKVAAPARAGAVAPEDIWVLAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGKRVGASEASLLNLLNISPFTYGLTVVQVYDNGQVFILDITDDELISHFISAVNTIACVSLAAGYPTLPSVGHSLINNYKDLLADYIYES-DDDM-GF-GLF Lacbi2 IYFEKLKELLNKYASIFLVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRYERLLPYVKGNIGFVFTDLKEIREIIVANKVAAPARAGAFAPKDVTVPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVVAGTRVGTSEATLLNMLNISPFTYGMTVVQIFDQGNIFVLDIDEKELIDRFLSGIKTVAAISLALNYPTIVSVTHTLVNAYKNLITEYTFEESDDDM-GF-GLF Lenti61 LYFQKLKELVAKYPSIFIVNVDNVGSNQMHQIRVSLRGVVMGKNTMVRRALRFERLLPHVKGNIGFVFTDLKEIRDIITANKVAAPARAGALAPKDVTIPGGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVQVVTAGTRVGPSEATLLNMLNISPFTYGMTVVQIFDQGNIFVLDISDKELLDRFFSGITTIAAISLAINYPTIVSVMHSLVNSYKNLITDYSFEESDDDM-GF-GLF Malgl1 NWFSRLNELIDTNTSIFVVNVDNVSSQQMHQIRQALRGVLMGKNTMVRRALRFERLMPHVRGNVGFVFTDLKEVRDKVIENRVAAPARAGAYSPVDIFVPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVEAGNRVSPSESALLNLLNISPFTYGMTVVQIFDNGNVFVLDVTEEELVGRFTQAVQQIASISLALNYPTIASVMHSFVNSYKNVLTDYEYEESDGDM-GF-GLF Mellp23 AYFTKLRDLMAEFPSAFIVNVDNVGSNQMHQIRQALRGVLMGKNTMVRRAIRYERLLPLVKGNIGFVFTDLKEVRDIITSNKVAAPAKAGAFAPLDVMVPAGNTGMEPGKTSFFQALGIPTKIQRGTIEIVSDIKIVTAGSRVGASEATLLNLLKISPFTYGMTVQMIYDNGNIFVLDIDEKTLIDNFLSGIKTIAAISLATNYPTLASVTHSLVNSYKNLITDYMFEEEDDDM-GL-DLF Mnele KYFVKMNRLLEEYPRIFIVGADNVRSKQMQQIRVSLRGILMGKNTMMNKAIRLEKLLPHIKGNVGLVFSDPVLVRDKLLENKVAAPARAGAIAPIDVIVEAQNTGMGPEKTSFFQALNISTKIAKGSIEIVSNVHLIHAGDKVGQSEATLLQMLNVQPFHYGLVVENIYDNGAVFVLDITDEQLLGKFQLGLSNVASVSLEIGYCTQASVPHSIINGFKNVLTDISFEESDDDM-GF-SLF Monbr LYFQRFYEYLEKFSRILIVHADNVGSKQMQDIRAALRGLLMGKNTMVRRAL-FHELLPHIKGNVGLLFTDFVAIRDVLLDHKVAAPARVGAIAPEPIIIPAGPTGQDAQKTSFFQALNIPTKIAKGSIEIISEVRLLEEGGRVGPSEAALLNMLGISPFSYGLVVVQIYENGACFILDITNDDLVAKFMEGSRKVAAVSLAIGRPNPASVPHMVINGYKNVLTEITFSEDDEEMDGF-SLF Morel2 EYFEKLKSYLEEFNSIFIVNVDNVGSNQMHEIRKALRGILMGKNTMVRRAIRYEKLMPSVRGNVGFVFTDLKTIRDKVLTNRVKAPAKAGALAPIDVFIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIINDVHLIKKDFRVGASEAALLNMLNISPFTYGLTVVQVYDQGTVFVLDIEEDALIGHFVAGIKNIAAISLQIGYPTVASVPHSIINSYKNLLTEYTFEESDDDM-GF-GLF Mucci2 LYFQKLTNYLDTYQSIFIVNVDNVSSNQMHQIRFSLRGVLMGKNTMVRRALKLEKLLNFVKGNIGFVFTDLKDIREKIVSNRVAAPARAGAVAPADVIVPGGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVKLVQSGSKVGPSEAVLLNMLNISPFTYGMGVVQVYDAGSLFVLDVEESQLVANLLAAIREIASISLAVGYPTLASVPHSVINGYKNLLSDYTFEEEDDDM-GF-GLF Mydma KYFAKIDKMLDEFPRCFLVTVDNVGSKQMQQIRIALRGVLMGKNTMMRKALKLEKILPYLVGNIGFIFTDLTEVRDLVLSNKKNAPAKAGSIAPLDVFIPAGNTGMGPEKTSFFQALSIQTKITKGTIEILSDIHLIKKDVKVGASEAALLAMLNIQPFYYGLVIKQVYDNGSIFILDISDDDIMKKFYSGVANVAAVSLAIGYPTAVSVPHSIVNGFKNVAADISIEPSDDDM-GF-GLF Neucr2 GYFDKLKGLLEDYRSIFIVSVDNVSSQQMHEIRQSLRGVLMGKNTMVRRALKYERLLPFVKGNVGFVFTDLKEVRDKILANKVAAPARAGAIAPADVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGAKVGPSEATLLNMLNISPFTYGMGIAQVYDQGNTFVLDISEEQLLKAFSTAITTIASLSLALNFPTLPSVIHSVVNAYKKVLTEISWSDED-DG-GFGGLF Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 AYFEKLRSLLNEYSTIFIVGVDNVSSQQMHEIRISLRGVLMGKNTMVRRALKWERLLPHVRGNVGFIFTDLKGTKEKILANRVAAPARAGAVAPDDVWIPGGNTGMEPGKTAFFQALGVPTKIARGTIEIVSDLKLVEAGNKVGASEATLLNLLNISPFTYGMTIAQVYENGQCFVLDITDEQLLGAFSKAISTITAVSLATNYPTLPSVMHSLINGYKKVLTDYSWESDE-DM-GF-GLF Phybl2 LYFEKLKTYLDTYQSIFIVNVDNVSSNQMHQIRFSLRGVLMGKNTMVRRALKFERILPHVKGNIGFVFTDLKAIREKITSNRVAAPARAGAVAPVDVIVPGGNTGMEPGKTSFFQALGIPTKISRGTIEIVSDVNLVAAGTKVGPSEAALLNMLNISPFTYGMSVSQVYDQGSAFVLDVEESQLIGNLLAAIREVASISLAVGYPTLASVPHSLINGYKNLLTDYTFDSEDDDM-GF-GLF Picst3 QYFSKLRELLEEYKSIFVVGVDNVSSQQMHEIRKALRGVLMGKNTMVRRAIRFEKLLPYVKGNVGFIFTDLKTIRDEIVSNVVAAPARAGAVAPKDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVEAENKVGPSEATLLNMLNISPFTYGMTVVQVYDNGQVFILDISDDELVGHFVSAINVIASISLAVGYPTLPSVGHSVVNHYKNVLTDYTFESEDDDM-GF-GLF Plicr1 EYFVKLKELLQKYPSIFLVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFEKLLPHVKGNIGFVFTDLKEIREIILANKVAAPARAGAFAPADVTVPAGNTGMEPGKTAFFQALGIPTKIARGTIEIVSDVKVVTGGTRVGTSEATLLNMLNISPFTYGMTVVQIFDAGNAFVLDIDEKDLIDRFLSSIKTVAAISLALNYPTLVSVSHTLVNAYKNLLTDYTFEESDDDM-GF-GLF Polpo TFIEKATKLFTTYDRMIIAQADFVGSNQLQKIRIALRGVLMGKKTMIRKVVRLEALLPHLKSNTAIIFANLTEIKSIVKGQRVGAPAKVGVFAPVDVIVPAGPTGLEPTQTSFLQDLKIATKINKGQIDIEKEVHLIKVGQKVGASEATLLQKLNIKPFTYGLEMKIVYDQGACY---ITEEDLIAKFKTGVANIAAISLEIGYPTVASIPHSLLNAYKNLLTEYSFEASDEDM-GM-GLF Pucgr2 AYFNKLKDLMAQFPSAFIVNVDNVGSNQMHQIRQALRGVLMGKNTMVRRAIRYERILPLVRGNIGFVFTDLKDVRDIITANKVAAPAKAGAFAPLDVYIPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDMKIVTAGSRVGASEATLLNLLKISPFTYGMTVVSIYDNGNVFVLDIDEKTLIDQFLSGIKTIAAISLAINYPTVASVPHSLVNSYKNLITDYMFEEEDEDM-GL-DLF Punst1 AYFVKLKELISSHPSIFLVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFERLLPHVKGNIGFVFTELKEIRDIITANKVAAPARAGALAPKDVFVAAGNTGMEPGKTSFFQALGIPTKIARGTIEIVNDIKVVTAGTRVGTSEATLLNMLNISPFTYGMTVVQIFDAGNSFVLDIDDDELVGRFLSGIKTIAAISLALNYPTIVSVVHSLVNSYKNLITDYTFEESDDDM-GF-GLF Rhior3 AYFQKLNDYLNTYQSIFIVNVDNVSSNQMHQIRVSLRGVLMGKNTMVRRALKLEKLLNFVKGNIGFVFTDLKDIRNKIVSNRVAAPARAGAVAPADVIVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVSLVQAGEKVGASEATLLNMLNISPFTYGMGVVQVFDKGTIFVLDVEESALVAKLMSAIREIASISLAVGYPTLASVPHSVINGYKNLLSDYTFESEDEDM-GF-GLF Rhoto1 AYFAKLKDYIETYPSIFVVNVDNVGSNQMHQIRQAVRGILMGKNTMVRRAIRFERFLPLVKGNVGFVFTDLKEIRDVIVSNKVAAPAKAGAFAPNDIYVPAGNTGMEPGKTSFFQALNIPTKIARGTIEIVSDVHLVVAGARVDASQATLLNMLGISPFTYGMKIIQIFSDGQLFVLDVSDDELLKRFMSGVTAVAAISLALNYPTLASVTHSLVNSYKNLLTEVSFEESDDDM-GF-GLF Rozal11 EYFLKLNNLFQDYSRVLVVSVDNVGSNQMHLIRKSVRGVLMGKNTMVRKAIRLEKLLPFIKGNVGFVFTDLKEVRDKVISYRIKAPAKAGAVAPCNVKIPAGNTGMEPGKTSFFQALGIPTKITKGLIEIISEVNLIQAGTKVGASEATLLNMMNVSPFTYGLEVVQVYDHGAVFILDITDETLLEYLTSAIRNIAALSMQLKVPSVASVPHHIINAYKNILTDYSFEESDEDM-GF-GLF Sacce1 EYFAKLREYLEEYKSLFVVGVDNVSSQQMHEVRKELRGVLMGKNTMVRRAIRFEKLLPFVKGNVGFVFTPLTEIKNVIVSNRVAAPARAGAVAPEDIWVRAVNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNKVGQSEASLLNLLNISPFTFGLTVVQVYDNGQVFILDITDEELVSHFVSAVSTIASISLAIGYPTLPSVGHTLINNYKDLLASYHYES-DDDM-GF-GLF Salro NYFAKLKSFLAEYPKILIVNCDNVGSKQLQNIRLALRGILFGKNTMMRRAI-YAELLPHIKGNVGFIFTDLAGIRDLLLNFKVAAPARVGAIAPDEVVVPKGPTGLDAQKTSFFQALNIQTKIARGAIEIVNDVKLLQKDDRVGPSEAALLNMLGISPFSYGLLPVQVYDNGSTYVMDITEEDIIGKLMLGAANVAAVSLACGLPNAASVPHMVANGYKNVLTEISFEESDDDMDGF-SLF Schco3 AYFEKLKELLQQFPSIFIVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRFEKLLPHVKGNIGFVFTDLKEIRDLIIANKVAAPARAGAYAPKDVSIPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVKVVTAGTRVGPSEATLLNMLNISPFTYGMTVVQIYDSGNTFVLDVDESELIDRFLTGIKTIAAISLALKYPTIVSVLHSLINSYKNVLTEYTFEESDDDM-GF-GLF Schpo1 QYFEKLRSLFEKYNSLFVVNIDNVSSQQMHTVRKQLRGLIMGKNTMIRRAMRLERLLPVVRGNVGFVFTDLKEVRETIIANVIAAPARPNAIAPLDVFVPAGNTGMEPGKTSFFQALGIPTKITRGTIEITSDVHLVSKDAKVGPSEATLLNMLNISPFTYGMDVLTIYDQGNVFILDVSEEDLIGHLLSAASIITAISLGANYPTILSVMHSVVNAYKNLVTEYTFEESDEDM-GF-GLF Sorma GYFDKLKGLLEDYKSIFIVSVDNVSSQQMHEIRQSLRGVLMGKNTMVRRALKYERLLPFVKGNVGFVFTDLKEIRDKILANKVAAPARAGAVAPADVWVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLVEAGVKVGPSEATLLNMLNISPFTYGMGIAQVYDQGNTFVLDISEEQLLKAFSSAITTIASLSLALNFPTLPSVMHSVVNAYKKVLTEISWSDED-DG-GFGGLF Sphar AYFERLLSYFDKYSKCFIVGVDNVGSNQMQQIRKSLRGVLMGKNTLIRKALRFHKLLSVVKNNVGFVFTDLCEVRDLITSFKVAAPAKTGAIAPIDVHIPAGSTGMDPGKISFFQALNITTKIQKGAIEIVNPVHLIKEDTRVDASAAVLLNMLKISPFSYGLKVFHVFEGGSLYVLDIKEDDLLKEFSAAVANVASISLAIGYPTVAAIPHMFINSYKNVLTDITFESEEEDM-GF-GLF Spipu1 VYFQKLSQLLEEYPTIFIVNVDNVSSNQMHQVRHSLRGVLMGKNTMVRRALRYEKLLTVIKGNVGFVFTDLKEIRERIVANRVQAPAKAGAVAPVDVTIPAGNTGMEPGKTSFFQALGIPTKIAKGTIEIVNDVPLIHAGSKVGASEATLLNMMNISPFTYGMTIQAVYDNGTIFILDIDESDLLASLVQGITTIAAVSMAIGYPTIASVPHLLINGYKNLITEYSFEESDDDM-GF-GLF Sporo1 AYFAKLKDLIETYPSIFIVNVDNVGSNQMHQIRQALRGILMGKNTLVRRAVRFERFLPHVRGNVGFVFTDLKEIRDIIVDNKVAAPAKAGAVAPNDVYVPAGNTGMEPGKTSFFQALNIPTKIARGTIEIVSDIHLVPAGQKVDASQATLLNMLNISPFTYGMKIIQIFSDGQLFVLNVSEDELLEKFMSGVKAIASISLAINYPTLASVTHSLVNSYKNLLTDITFEESDDDM-GF-GLF Stehi1 LYFVKLKELIAKFPSIFIVNVDNVGSNQMHQIRVALRGVLMGKNTMVRRALRLERLLPHVKGNIGFVFTDLADIRDIITANKVAAPARAGAFAPLDVTIPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVKVVTAGSRVGSSEATLLNMLNISPFTYGMTVVQIYDQGQVFVLDVDAQELVDRFLTGIKTIAALSLALNYPTIVSVSHSLVNAYKNLITDYTFEESDDDL-GF-GLF Tapde11 EYFEKLKSLVEEYKSCFVVTVDNVGSQQMHLIRKSLRGVLLGKNTMIRRALRLERLVPLVRGNMGFVFTDLKDIREKIVNNTVAAPARAGALAPLDVFIEAGNTGMDPSKTSFFQALGVPTKIARGTIEIVGQVQVVTKGTKVGASEATLLNMLNISPFTYGMKVATVYDNGQVFVLDITEDVLIGQFMSAVRNVACISLAAKYPTIVSVMHSVINAYKNLLTDYTFEASDEDM-GF-GLF Thetr AYYDKVVALFQEYSKVILVDADNVGSSQMQQIRIALRGLLMGKNTMIRRALRIERILPLIVGNVGLVFTEPAEIRALIGANRVGAPAKAGAIAPCDVDVPAGPTGMEPGLTAFFQALNIATKIARGQIEIVADIKLITKGDKVSASEAVLLQKLGIKPFSYGLEAKTIYDDGVVYVLDLTSEDIGAMLANAAKDIGAISLAIDYPTVVSVPHSILNGFKNVMSEYTIDDSSSEMSGMFDMF Treme1 LYFEKLKVLIAEYPSIFLVNIDNVSSQQLHLIRQALRGVLMGKNTMVRRALRFERLLPHIKGNIGFVFTDLKDVREIIISNKVAAPARAGALAPNDVYVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDVQVLTAGGRVGSSEATLLNMLNISPFTYGMSVVQVYDNGAVFVLDVEESTLLERFMTGIKTVAAISLATGFPTIASVTHSLVNSYKNILTEYEFEESDDDM-GF-GLF Trire2 GYFDKLKGLLQDYKSIFIVEIDNVSSQQMHEIRHSLRGVLMGKNTMVRRALRYERILPFVKGNVGFVFTDLKEIRDQLLANRVAAPARAGAVAPVDVWVPAGNTGMEPGKTSFFQALGVPTKIARGTIEITTDLKLIDAGNKVGPSEASLLNLLNISPFTYGMGIAQVYDQGQTFILDIGEEQLLKALSTAITTVATISLAINFPTLPSVMHSLVNSYKKVLTEYSWEDEE----GFGGLL Umbra1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 AWFEKLTELLEKYPSIFIVNIDNVSSQQMHQIRQSLRGVLMGKNTMARRALRYERLLPHLKGNIGFVFTDLKDVRDVILSNRVAAPARAGAYAPADIFVKAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDVKVVDAGNRVGTSEATLLNMLNISPFTYGMTVVQIYDRGQCFVLDVSEDELVDRFVLGIKQVACISLALNYPTIASVMHSLVNGYKNLITDYEFEESDDDM-GF-GLF Walse1 QYFNRLQELVETYPSIFIVNIDNVSSNQMHQIRQALRGVLMGKNTMVRRALKFERLLAHVKGNIGFVFTDLKDIRDIIVANKVKAPARAGLYSPEDVYIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDIRVVEANTRVGASEATLLNMLNISPFTFGMTCVQVYDNGQIFVLDVSEETLVGRLLTAGNQIAAISLAINYPTLPSVMHSFVNSFKNVLTDYTFEDEDEDM-GL-GLF Zygro1 EYFSKLREYLEEYKSIFVVGVDNVSSQQMHQVRRALRGILMGKNTMVRRAVRYEKLLPFVKGNVGFVFTSLKDIKEVIVANKVAAPARAGAIAPGDIWVTAMNTGMEPGKTSFFQALGVPTKIARGTIEISSDVKVVEAGNRVGPSEAALLNLLNISPFTFGLVITQVYDDGQIFILDITDEELVGHFVSAVTTIASVSLAVGYPTLPSVGHSIINSYKDLLSKYIYES-DDDM-GM-GLF [Cluster1735.fasta_al_trimmed; alignment length = 195] Allma1 KQRVLVCSSRGINHRRHLLQDLVTLLPHSKKESKLDQKKNLLNEIAELTSCNKVIYLEARRDTYMWLSHPNGPSIKFQVLNIHTMDELN--MTGNHLKGSRPILSFDAAFDTRVIKELLTQTFNTPRKSKPFFDHVMAFTWADN-KVWVRNYQLTESLTEVGPRFVLDPIKVFQGSFGGITLWESATYLTPAAVR Ashgo11 KQRVLLISSRGVTYRRHLIQDLHSLMPHSRKEPKLDTKKDLLNEIAELYNCNNVAFFEARKDLYMWLSKPNGPTVKFYLQNLHTMDELN--FTGNCLKGSRPVLSFDKRFDYRLFKEMFIHTFGVPRKSKPFIDHVMSFSIVDD-KIWVRNYEISHSLVEIGPRFVMTPILILEGAFGGPKIYENKQYVSPNVVR Aspfu1 KTRVLMLTSRGVTYRRHLLSDLCALLPHTHKESKLDTKKKTLNSLADLHSCNVIFFLEARKDLYLWLARPNGPTIKFHVTNLHTMGELNTGFSGNCLKGGRGIVVFDRSFDRGLIREMLRGVFCVPKGMKPFIDRVIGVFGVDG-KIWIRVYEIRESLVEIGPRFVLTPIVILEGSFGGPVIYENKEYVSPNQVR Aurde31 -----MLSSRGVTARRHLMADLASLMPHAKKDAKLDAKNQLLPELADLHSCNNALYFEARRDLYMWAAKPNGPSIKLHVQNSHTMDELK--MRGNCLKGSRPVLSFAKEFDGRLCKEVFTHIFGVPRRAKPFVDHILSFSILDG-KIWFRNFQIIESLVEIGPRFVLTPIRIFEGAFSGATVYSNPEFVSPAAAR Batde5 KQRVLLIASRGITYRRHLMNEMHTLLPHSKKDAKLDSKSHLLNELAELNNCNNCLYFEVRKDMYLWMSKPNGPSVKFMVRNVHTMDELK--MTGNCLKGSRPVLSFDKTFDLQLLKEMFTQTFAVPRKIKPFIDHIMSFSILDN-KIWLRNFQIIESLVEIGPRCVLDIIRIFDGSFGGSTLYENTLFVSPNELR Botbo1 KQRVLMLSSRGVTHRRHFMNDLEALLPHVKKDSKLDSKNHLLPELADLNNCNNALYFEARRDLYMWAAKPNGPTVKMHVQNIHTMDELK--MTGNCLKGSRGLLCFDQVFDWKLMKEIFTHIFGVPRRSKPFIDHILTFSIVDS-KIWFRNFQILESLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFISPAAVR Botci1 KQRVLILSSRGITYRRHLLNDLASLLPHGKKDAKLDTKSKLLNELAELYNCNNVFFFEARKDLYLWMSKPNGPTVKMHMQNLHTMEELH--FTGNCLKGSRPILSFDASFDLRVLKELFLHIFGVPRKSKPFIDHVMGFTLADG-KIWIRNYQISENLVEIGPRFVLTPIVIQEGSFGGPIIYENKEFVSPNQVR Caeel RERVLVLCSRGADVRRYLMKDIKDLLPHAKGDSKLDQQKSLLNEIAEMKNCTKVMYFESRKDTYLWMSNEKGPSIKFLVHNVHTMKELK--MSGNCLRASRPVLSFDDAFDLKLIKAVLMQTLGTPPRSQPFVDHVFNFSVGEGDKIWFRNFQIVDQLQEVGPRFVLEMVRLFAGSFEGAVLYDNPNYVSPNVIR Canalb1 RQRLLVISSRGITYRRHLIQDLLALLPHARKEPKFDSKKNLLNEVAELYNCNNIFFFECRKDLYLWISKPNGPTLKFHIQNLHTLDELN--FTGNCLKGSRPILSFDKSFLYKLLKEMFLQTFGVPRKSKPFIDHVMTFSIVDG-KIWIRNYQINENLVEIGPRLVLTLITVLEGSFSGPKIYENKQYVSPNFVR Cangl KQRTLLISSRGVNYRRHLIQDLHSLLPHTRKEPKLDTKKDLLNEIAELYNCNNIMFFEARKDLYLWMSKPNGPTIKFYVQNLHTMDELN--FTGNCLKGSRPILSFDNRFDYQLIKEMMIHNFGVPRKRKPFIDHVMSFSIVDD-KIWVRTYEISHSLVEIGPRFVMTVILVLEGAFGGPKIYENKQYVSPNAVR Capow KQRTLVLSSRGVTYRRHLLNDLRTLMPHSKKDVKMDKKDKLVNEVCELKNCNNCIYLETRKDAYLWLAKPSGPSVKFHIDSINTMDELR--MTGNCLKGTRPLLSFDKNFELQLLKEIFTQVFGTPPKSKPFFDHVFTFSIVDN-RVWFRNFQIIDTLNEVGPRFVLNTIRIFDGSFGGATIFENPDYVSPNEIR Catan2 KQRVLVCSSRGVTHRRHLMSDLLCLLPHSKKENKLDQKKHLLNEIAELTSCNKVLYLESRRDLYMWMSHPNGPSIKFEVLNVHTMDELN--MTGNHLKGSRAILSFDSSFDTQLIKELLTQTFNVPRRSKPFFDHVLMFAWVDN-KVWVRNFQITEALNEVGPRFVLNPIKLFQGSFGGIGLWENPDYMTPAAVR Cioin KQKVLVFTSRGITYKRHLVNDLRNLMPHTKTDVKMDRKSDLVNEICEIKSCNKCIFLVGKKDVYMWISNPHGPSALFHVEYLNMMEELK--FTGNCLKASRPILSFDSKFDMKLLKELFIQVFGTPPKSQPFVDHVFTFSLMDG-KIWFRNYQIVE-LVEIGPRYTMTLSRILSGSFGGPILYINPDYQSPNLVR CocheC53 KQRVLILSSRGVTFRRHLLQDLYSLMPHSRKEAKLDTKTKLLNELAELYNCNNVLFFEARKDLYCWMSKPNGPTVKMHLQNLHTMEELN--FIGNCLKGSRPILSFDAAFDLRVIKELFTQIFGVPRKVKPFVDHVMGFTVTDG-KIWVRVFQINESLVEIGPRFVLTPIVIQESSFGGPIIYENKEFVSPNQIR Coere1 KNRVLMVASRGITFRRHLLNDLEALLPHTKKEAKIESKQDMLNELAEIQNCNSVFYFEARKDLFMWISRPSGPSVKFLVQNIHTMDELK--MTGNCLKGSRPVLSFDATFDLQLLKEMLTQTFGVPRKSKPFFDHVFTFSVVDN-RIWFRNYQISETLIEIGPRFVLNPIRIFEGSFGGPTLYENPRYISPNAVR Conco1 KQRVLILCSRGITFRRHLMNDLEALMPHAKKDSKLDSKQNLLNELAEMNNCNNCLYFEARKDLYLWISKPNGPSAKFHIQNIHTMSELK--MTGNCLKGSRPLLSFDALFDYKVLKEMFVQTFGVPRKLKPFIDRIYSFSIVDN-RVWFRHYQIVETLVEIGPRFCMNLIRIFEGSFRGTTLYDNPLYVSPNMVR Conpu1 KQRVLLLSSRGITHRRHLMNDLEALLPHVKKDSKLDSKSQLLPELADLNNCNNTLYFEARRDLYLWAAKPNGPSIKMHVQNVHTMDELK--MTGNCLKGSRGILSFDKAFEGRLTKELFTHIFGVPRRAKPFIDHILSFSILDN-KIWFRNFQIMESLVEIGPRFVLTPIRIFEGAFHGATVYSNPEFITPTAVR Copci KQRVLLLSSRGVTHRRHLMNDIEALLPHVKKDAKLDSKNQLLPELADLNNCNNTLYFEARRDLYLWAAKPNGPSIKMHMQNIHTMDELK--LTGNCLKGSRGLLSFDASFDGRLTKEIFTHIFGVPRKAKPFIDHILTFSILDN-KIWFRNFQIVESLVEIGPRFVLTPIRIFEGAFHGATVYSNPEFISPAAVR Croqu1 KSKVLILCSRGITYRRHLMNDITDLVTHGKKDAKLDSKHALINELADLSSCNHALYFESRRDLYLWAAGPNGPSIRFHVVNSHTMDEMK--MTGNCLKGSRPIVRFGQEFDWRVCKEVLTNIFAVPRRAKPFVDHVISFSVIDG-KIWFRNYQILNSLSEIGPRFVLVPVKIFEGSFGGPCLWENKEFVPPFQVL CryneH991 KDKVLMLSSRGVTQRRHLMRDLEALLPHVKRDSKLDTKSSLLNELADLHSCSNTLYFEARRDLYLWLSRPNGPSVKCHVQNLHTMDELK--MTGNCLKGSRGLVCFDGSWEG-LMKEMFTHVFSVPRKLKPFIDHILLFSLLDN-KIWFRNYQIIESLVEIGPRFVLTPIKIFEGSFGGPTIFSNSEFITPAAMR Crypa2 KQRVLVLSSRGVTYRRHLLNDLAAMMPHGRKDAKFDSKSKLLNELAELYNCNNVLFFEARKDLYMWASKPNGPTVKMHVQNLHTMEELH--FTGNCLKGSRPVLSFDAAFDLMVIKELFFHIFGVPRKSKPFVDHVIGFTVADG-KIWVRNYQINENLVEIGPRFVCTPIIIQEGSFGGPIIYENKQFVSPNQVR Debha1 RQRLLVISSRGVTYRRHLISDLVALLPHARKEPKFDSKKNLLNEVAELYNCNNIFFFESRKDLYLWISKPNGPTLKFHIQNLHTLDELN--FTGNCLKGSRPILSFDKSFEHKLLKELFTHTFGVPRKSKPFVDHVMTFSIVDN-KIWIRNYQINESLVEIGPRFVLTLITILEGSFGGPKIYENKEYVSPNFVR Dekbr2 RQRVSLISSRGVTFRRHLLNDLYALLPHSRKEPKLDTKKSLLNELAELYNCNNIMYFEARKDLYMWLSKPNGPTIKFYIQNLHTMEELN--FTGNCLKGSRPILSFDKAFDYQLMKEMFTQQFGVPRKSKPFIDHVMTFSIVDE-KIWIRNYQINESLVEIGPRLVLTPIIILEGSFGGPKIFENKQYVSPNVVR Dicdi KKRVLFTSTRGIGSKRHLMADLISLIPHSKKEDKIDDRKTLINETCEMKSCNYAILFDVRKDCFLWMAKPLGPTVKFHITNVHTLDELQ--MTGNCLKGSRPFLHFDKSFDLQLIKELITQIYSTPVKSKPFFDHVFSFFYQDG-RIWFRNYQISDLLTEIGPRMIMHIDKIFSDGFGGSVLYSNPNYVSPNNTR Dmel KQRVLVFSARGISHRRHLMKDIKTLMPHHRPESKMERSKTLVNEMCEMKHCNKAMLFEGRRDLYMWISNSTGPSAKFLIENIHTMAELK--MTGNCLRGSRPLLSFDSKFDLKLLKELFVQTYSVPPKSQPFVDHVFTFTYLDK-RIWFRNFQIL-GLSEVGPRYVMNPVKIFDGSFTGKTIWENPDYVSPSKQR Enthi WSRCLILASRGVSAKRYLMQDLISMIPHNKKEPKFDDKRHFIAEICDLRNCDTCIFFENRKDLYLWFCCPHGPSIKFFVENITTMSNLK--LTGNALKGSRPIISFGAEFDNKIIKEILSKIFHVEPKSKPFIDHILQFSIVDD-RIWMRNYQIVDSLVEIGPRYCMRCIKILSGCFSGSVVYLNEKYVSPNVIR Falba KQKTLILSSR-----------------------------------------------------------------------VHTLEEMR--LTGNALKGTRPLLSFDKSFDLSLIRELLIQVIGTPPRSRPFFDRVMTFSHVDG-RIWIRNYQVIRRTEEIGPRAVFTPIRIFDGSFQGRTLYKNPDFVSPNLYR Fomme1 KQRVLLLSSRGVTHRRHLMNDLEALLPHVKKDSKLDSKSQLLPELADLHNCNNTLYFEARRDLYLWAAKPNGPSIKMHVQNIHTMDELK--LTGNCLKGSRGIVCFDKGFDGKLTKEVFTHIFGIPRRAKPFIDHILTFSLLDN-KIWFRNFQILESLVEIGPRFVLTPIRIFEGAFSGATVFANPEFVSPAVVR Fusgr1 KQRVLILSSRGVTYRRHLLNDIASMLPHSRKDAKFDSKTKLLNELAELYNCNNVLFFEARKDLYVWLSKPNGPTIKFHLQNLHTMEELH--FTGNCLKGSRPVLSFDGAFDLRLIKELFLHTFGVPRKSKPFIDHVMGFSFVDG-KIWVRNYQVNENLVEIGPRFVLTPIVIQEGSFGGPIIYENKEFVSPNQVR Galma1 KQRVLLLSSRGITHRRHLMNDLEALLPHVKKDSKLDSKSQLLPELADLNNCNNTLYFEARRDLYLWAAKPNGPSIKMHVQNVHTMDELK--MTGNCLKGSRGLVSFDKAFEGKLTKEVFTQIFGVPRRAKPFIDHILTFSIVDS-KIWFRNFQIVETLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFVSPAAAR Ganpr1 KQRVLLLSSRGITYRRHLLNDLHALLPHSKKESKFEQKTELLNEVAELANCNNAIFLECRRDLYLWMAKPNGPSVKFFVQNVHTMDELR--LTGNCLKGSRPIVSFDKNFDLSLLKEMFTQIFATPRKIKPFVDHVLNFSVVDN-KIWFRNYQVVESLVEIGPRFVLDIVRIFDGSFCGATLYENPTFVTPAQV- Gloin1 KQRVLALSSRGINYRRHLLNDLEALLPHFKKDSKLDTKFKLLNELAELNNCNNC-------DLYMWTSKPNGPSIKFHVQNIHTMDELK--MTGNCLKGSRHILSFDKNFELILIKEVFTHIFGVPRRSKPFIDHVISFTIADN-RIWFRNFQIVESLVEIGPRFVLNVIRIFEGSFCGATVYANPEFITPNQIR Hisca1 KTRVLMLTSRGVTHRRHLLSDLTSLLPHTHKESKLDTKKKTLNSLADLHSCNVIFFLEAKKDLYLWISRPNGPTIKFSVSNLHTMGEMGTGFAGNCLKGGRGVVVFDKTFDRGLIREMLRSVFSVPRGMKPFIDRIIGVFGVDG-KIWIRVFEIRETLVEIGPRFVLTPIVILEGSFGGPVIYENKEFVSPNQVR Klula1 KQRTLLITSRGVTYRRHLVQDLNSLLPHSRKEPKLDTKKDLLNEIAELYNCNNIIFFEARKDLYLWLSKPNGPTIKFYLQNLHTMDELN--FTGNCLKGSRPILSFDGRFDYRLIKELFIHNFGVPRKSKPFIDHIMSFSIVDE-KIWVRTYEISHSLVEIGPRFVMTPILILEGSFGGPKIYENRQYVSPNFVR Lacbi2 KQRVLLLSSRGITHRRHLMNDLETLLPHVKKDSKLDSKSQLLPELADLNNCNNTLYFEARRDLYLWAAKPNGPSIKMHVQNVHTMDELK--LTGNCLKGSRGLLSFDRAFEGRLTKEVFTQIFGVPRKAKPFIDHVLTFSILDS-KIWFRNFQIIETLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFISPAAVR Lenti61 KQRVLMLSSRGINHRRHLMNDLEALLPHVKKDSKLDSKNHLLPELADLHNCNNTLYFEARRDLYMWAAKPNGPSIKMHVQNVHTMDELK--MTGNCLKGSRGILSFDKAFDGKLTKELFTHIFGVPRKAKPFVDHVLTFSILDN-KIWFRNFQIIESLTEIGPRFVLTPIRIFEGAFSGATVYSNPEFVTPAAVR Malgl1 KQRVLMLPSRGITARRHLINDLEALLPHAKKDSKLDSKSDLLNELADLNNCNNCMYFEARRDLYLWLSKPNGPSAKLLVQNVHTMDELK--MTGNCLKGSRHILSFDKGFDWTLMREMLTQIFGVPRRAKPFVDHILSFSILDN-KIWFRNYQIIETLVEIGPRMVMTPIRIFEGSFGGPTLFDNPEFISPNAVR Mellp23 KSKVLILCSRGITYRRHLMNDISDLVTHGKKDAKLDSKHALINELADLSSCNYALYFESRRDLYLWASGPNGPSIRFHVVNSHTIDEMK--MTGNCLKGSRPILQFGQEFDWRVCKEVLTNIFAVPKRAKPFVDHVITFSVIDG-KIWFRNYQILESLSEIGPRFVLVPIKIFEGSFGGPCLWENKEFVPPFKVL Mnele KQRALVFAARGITFHRHLMNDLKVLMPHAKSDSKLERKEGLINEICEMKNCNMTMFFEMRKDLFMWLSMPNGPSARFLVQNVHTMDELR--LTGNHLKSSRPLLTFNKAFDLSLIKEMLKQMFATPPKSKPFYDHVLGFTYLDG-RIWFRNFQITDSLVEVGPRFCLWLIKIFSGSFSGNVIYENPNYKSPNQYR Monbr RQRTLVFSSRGISFQRHLLQDLRVLMPHSKKDVKMDRKDRLVPEICEMKNCNNCIYIEMRKDVYMWMSKPMGPSVKFLVTDIYTMSELK--LTGNCLRGSRPLLQFDQAFDYQLLKEILFQTFATPPKSKAFVDHIFSFSILED-RIWFRNYQVTWVLTEIGPRFCLQVIRIFEGTFGGPTLFENADYVSPNMQR Morel2 KQRVLLLSSRGITSRRHLLTDLGDLLPHTKKDAKLDSKSKLINELAELNNCNNCIFFEVRKDLYMWLSKPNGPSVKFHIQNIHTMEELK--MTGNCLKGSRHILSFDKNFEWLLMKELFTQVFGIPRRIKPFVDHVLSFSIVDN-RVWFRNYQITETLVEIGPRFVMNPIRVFDGSFGGQTAFENPEFVSPNVAR Mucci2 KQRVMMLSSRGVTFRRHLLTDLEALLPHSKKDAKLDTKNNLLNELADLNNCNNAVFFEVRKDLYVWMAKPNGPSVKFHLQNLHTMDELK--MTGNCLKGSRHILSFDKTFDWGLLKELLGQVFNVPRRSKPFIDHVLSFSIVDN-RVWFRNYQIVESLVEIGPRFCLTPIRIFEGSFGGPTVFENPEFVHPNFVR Mydma ------------------MLDLRTLMPHSRADNKLDRKDRLINEICEMKNCNKCIFFEMKKDLYMWISNPNGPSARFLVENVHTMDELK--LTGNSLKGSRPILSFDKKFDHKLLKEMFMQAFATPPKSKPFIDRVMTFTIVEH-RIWIRNFQML-SLTEIGPRFVLNLIRIFNKSFCGSTIYENPHYISPNEHR Neucr2 KQRVLILSSRGVTYRRHLLNDLAAMLPHGRKDVKFDSKSKLLNELAELYNCNNVMFFEARKDLYMWFSKPNGPTVKFHAQNLHTMEELH--FTGNCLKGSRPLLSFDLAFEYRVIKEVFLQMFGVPRKSKPFIDHVMSFSIADG-KIWVRNYEIRESLVEIGPRFVLTPIIIQEGAFGGPIIYENKRFISPNQVR Orpsp11 ----------------------------------------------------------------------------------HTMSELH--LTGNCLKGSRPIVSFDKTFDYKLIKEVLLHNFSTPRRIKPFVDHVITFSIVDG-RIWFRNYQIVESLVEIGPRFVLQVMRIFDGSFCGSTLYKNGEFVSPNMIR Pench1 KTRVLILTSRGASFRRHLMSDICGLLPHAHKETKLDTKKKALNSLADLHSCNVIFFLEAKKDLYLWLSRPNGPTIKFHLNNLHTMGELGAGFAGNCLKGGRGLVVFDRSFDRALVREMLRGVFCVPRGMKPFIDRIIGIFGVDG-KIWIRVYEIRESLVEIGPRFVLTPIVILEGSFGGPVIYENKEYVSPNQVR Phybl2 KQRVMLLSSRGVNFRRHLLTDLEGFLPHSKKDAKLDTKNNLLNELAELNNCNNAIFFEVRKDLYLWMSKPNGPSVKFHVQNLHTMDELK--MTGNCLKGSRHVLSFDKTFDWSLLKELLAQVFNVPRRSKPFIDHVLSFSIVDN-RIWFRNYQIVESLIEIGPRFCLTTIRIFEGSFGGPTVFENPEFVHPNFIR Picst3 RQRLLVISSRGVTYRRHLISDLLALLPHARKEPKFDSKKNLLNEVAELYNCNNIAFFEARKDLYLWLTKPNGPTVKFHVQNLHTLDELN--FTGNCLKGSRPVLSFDKSFLYRLLKELFTHTFGVPRKSKPFVDHVMTFSIVDN-KIWIRNYQINENLVEIGPRFVLTLITILEGSFGGPKIYENKEYVSPNFVR Plicr1 KQRVLLLSSRGITHRRHFMNDLEALLPHVKKDSKLDSKSQLLPELADLNNCNNTLYFEARKDLYMWAAKPNGPSIKMHVQNVHTMDELK--MTGNCLKGSRGLLSFDQAFDGRLTKEVFTHIFGVPRRVKPFIDHILTFSILDS-KIWFRNYQILETLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFISPAAVR Polpo KKRVLVMSTRGISPKRHLMGDLLDLIPHSKKESKLDDRKSLINESCEMKSCNYAILFDSRKDLYLWMAKPLGPTIKFGVSNVHTLEELQ--MTGNCLKGSRPFLHFDATFDLQLAKELLTQIFSTPVKSKPFFDHVFAFFYQDG-RIWFRNYQISDLLTEIGPRMILHISKIFSGGFGGQVLYSNPEFVSPNDNR Pucgr2 KSKVLILCSRGITYRRHLMNDLANLITHGKKDAKLDSKHALINELADLNSCNHALYFESRRDLYLWASRPNGPSIRFHVVNVHTMDEMK--MTGNCLKGSRPIVTFGKEFEWKVCKEVLTNVFAVPRKAKPFVDHIISFSIVDG-KIWFRNYQILQSLTEIGPRFVLTPIKLFEGSFSGPCLWENKEFVPPVQAL Punst1 KQRVLMLSSRGITHRRHLINDLEALLPHVKKDAKLDSKNHLLPELADLHNCNNTMYFEARRDLYLWAAKPNGPSIKMHVQNIHTMDELK--MTGNCLKGSRGLLSFDAAFDGKLTKEVFTHIFGVPRRAKPFIDHILTFSLLDG-KIWFRNFQILETLVEIGPRFVLTPIRIFEGAFGGATVFSNPEFISPAAVR Rhior3 KQRVMMLCSRGVTYRRHLMNDLEGLLPHSKKDAKLDTKNNLLNELADLNNCNNAVFFETRKDLYVWMAKPNGPSVKFHLQNLHTMDELK--MTGNCLKGSRHILSFDKTFDWSLLKELLG--------------------------------QVVESLVEIGPRFCLTPIRIFEGSFGGPTVYENPEFVHPNFVR Rhoto1 KQRVLVTSSRGISQRRHLMTDLLALLPHAKKETKLEDKHNLINELCYLSSCNNALFFEARRDLYLWAAKPNGPSVRFHVLNLHTMDEMK--MTGNCLKGSRPVVVFDKQFDWKLIKEVLTHIFAVPRRAKPFIDHVINFSIADG-KIWFRNYQILDSLSEVGPRFVLNPVKIFEGSFNGACLYENKEFVPSSARF Rozal11 KEKTLVLCSRGSTSRRHLMKDLMMLLPHAKQESKFDSKKETVNELMELNNCTSCLYFEARKDLYLWMAKVTGPSLRFLIQNIHTLDELR--MQGNCLKGSRPVLSFDSSFDFALVKECLKQIFHTPRKSKPFVDRVMSFSIADN-KIWVRNFQIADSLVEIGPRFVMTLQRIMDGCFSGPVLYENPDFVSPNVVR Sacce1 KQRTLLISSRGVNYRRHLIQDLSGLLPHSRKEPKLDTKKDLLNEIAELYNCNNVLFFEARKDLYLWLSKPNGPTIKFYIQNLHTMDELN--FTGNCLKGSRPVLSFDQRFEYQLIKELLVHNFCVPRKSKPFIDHVMSFSIVDD-KIWVRTYEISHSLVEIGPRFVMTVILILEGSFGGPKIYENKQYVSPNVVR Salro RQRTLVFSSRGISFRRHLLSDLRALLPHSKKEVKMERKDRLIPEICEMRNCNNCLYFEMRKDVYLWVSKPHGPSIKFYVTNIHTMDELR--LTGNCLKGSRPLVHFSKEFDFRLMKELLFQSFGVPPKSKPFVDHVVSFYVLDE-RIWFRHYQVVWRLVEIGPRMVLQPIRMFEGSFGGPTLWKNAEYEPP---R Schco3 KQRVLMLSSRGVTHRRHLMNDLETLLPHVKKDSKLDSKQQLLPELADLNNCNNTLYFEARRDLYMWAAKPNGPSIKMHVQNIHTMDELK--MTGNCLKGSRGLLSFDKGFDGRLTKEVFTHIFGVPRKAKPFIDHILTFSLLDN-KIWFRNYQILESLIEIGPRFVLTPIRIFEGAFSGATVFSNPEFVSPASVR Schpo1 KQKVLVLSSRGVTYRRHLLNDLVSMMPHSKKDSKLDSKDRLLNELAELYNCNNIFFFESRRDLYLHIARPNGPTVKFHVENLHTMDELN--MTGNALKGSRPILSFDKTFDLKVVKELLQQTFGIPRRSKPFIDRVCTLTIADG-KIWFRNYEIRETLIEIGPRFVMTIINILEGSFGGPVIYKNDTFVSSTMVR Sorma KQRVLILSSRGVTYRRHLLNDLAAMLPHGRKDVKFDSKSKLLNELAELYNCNNVMFFEARKDLYMWFSKPNGPTVKFHAQNLHTMEELH--FTGNCLKGSRPLLSFDGAFEYRVIKEVFLQMFGVPRKSKPFIDHVMSFSIADG-KIWVRNYEIRESLVEIGPRFVLTPIVIQEGAFGGPIIYENKRFISPNHVR Sphar KQRVLIFSSRGTSFRRHLLTDLRDLTPHSKHDVKLDRKDQLVNEVCELKNCNNCVFLEMKKDLYMWLSKPNGPSAKFLVENVHTMSELK--LTGNCLKGSRPILSFDKNFDWALLKELLLHSFGTPPKSKPFVDRVLSFSIADG-RIWFRNYQIIKSLVEIGPRFCIQPIRVFSGSFGGQTLYENPEYRSPNELR Spipu1 KQRVLLLSSRGITERRHLLKDLGTLMPHSKKESKLDSKHQLLNELAELSNCNNCLYFEIRKDLYMWMSKPNGPSVKFHVQNVHTMDELR--MTGNCLKGSRPILSFDKNFDYQLLKEMFTQTFGSPRKLKPFIDHVLSFSIADD-KIWFRNYQIVESLIEIGPRFVLSVMRVFDGSFGGSTLFENREFVSPNEIR Sporo1 KQRVLTISSRGISQRRHLMADLISLLPHSKKDAKLEDKHSLLNEIAYLSSCNNILFFEARRDLYLWAAKPNGPSCRFHVLNAHTMDEMK--MTGNCLKGSRPIVVFDQQFEMKLIKEVLTHIFAVPRRAKPFVDHVINFSIADG-KIWFRNYQV--SLTEVGPRFVLNPVKIFEGSFNGACIYENKEFVPSSALA Stehi1 KQRVLLLSSRGITHRRHLMNDLEALLPHVKKDSKLDSKNQLLPELADLHNCNNTLYFEARRDLYLWAAKPNGPSVKMHVQNVHTMDELK--MTGNCLKGSRGLLSFCGGFEGRLIKEMFTHIFGVPRKAKPFIDHILTFSLLDN-KIWFRNFQIIESLVEIGPRFVLTPIRIFEGAFSGATVFSNPEFVSPTVVR Tapde11 KQKVLVLSSRGITARRFLLNDLTALLPHSKKDTKLDTKSKLLNEVAELYNCNNIMFFESRKDLYMWLAKPNGPSFKLHIQNLHTMDELN--LTGNCLKGSRPVLSFDASFDFRLLKELMSQVFGVPRRSKPFVDHILTLSIVDN-KIWFRNYQIQEELIEIGPRFCMTMICILEGSFGGPLIYENKEFVSPNQVR Thetr KQRTLVFGTRGLTTRRHLLNDLRLLLPHSKKEVKMDAKDKLINEIAELKACNSCIFFEARKDLYLWISRPHGPSVKFHVLNIHTLDELK--LTGNALRGSRPVLSFDAAFDLKLLKEIFIQVFGTPPKSKPFVDHVLNFAYIDG-KIWFRNYQMFDKLVEIGPRMVLNIVRIFDGSFCGATLYENPNYVSPNLAR Treme1 ---------------RHLMRDLEVLLPHSKKDSKLDSKSSLINELAELNSCSNALYFEARRDLYMWLSRPNGPSVKFHVQNLHTMDELK--MTGNCLKGSRGVVVFDGRWEG-LLKEMLAHVFSVPRRLKPFIDHILLFSVLDG-RIWFRNYQIIYSLVEIGPRFVLTPIRIFEGSFGGPTVYANSEFVSPASVR Trire2 KQRVLILSSRGFAHRRHLLNDLASLLPHGRKDAKFDSKSRLLNELAELYNCNNVLFFEARKDLYVWLSKPNGPTVKFHLQNLHTMEELH--FTGNCLKGSRPILSFDAAFEFRVMKELFLHTFGVPRKSKPFIDHVMGFSIADG-KIWIRNYQISENLVEIGPRFVLTPLVIQEGSFGGPIIYENREFVSPNQIR Umbra1 KQRVLLLSSRGITYRRHLMNDLEAILPQAKKDSKLDSKSHLLNELAELSNCNNCIFFEVRKDLYMWISKPNGPSAKLHIQNIHTMDELK--LTGNSLKGSRHMLSFDKNFDYQLLKEMFTQVYGVPRRSKPFIDHILSFSIVDN-RIWFRNYQIVETLVEIGPRFCMTVIRVFEGSFGGSTVFENPEFVSPNMIR Ustma22 KQRVLMLPSRGVTSRRHLINDLESLMPHAKKDSKLDSKSQLLNELAELNNCNNALYFEARKDLYMWASKPNGPSAKFQVQNIHTMDELK--MTGNCLKGSRPILSFDKEFDWTLVKEMFTQMFGVPRKAKPFVDHVISFSIVDN-KIWFRNYQIVEKLVEIGPRMVLSPIRVFEGSFGGATVFENPEYISPNAIR Walse1 KQRVLVLSSRGVTERRHLMSDLQALLPHTKKDSKISSKTSLLNELADLASCNNIMFFETKHDLYLWLAKPNGPSVKFHLQNLHTMDELK--MTGNCLKGSRGILSFGEEFDLQLLKELFTHTFGVPRRVKPFFDHVLSFSYLDG-KIWFRSHQIVETLVEIGPRFVLTPIRIFEGSFGGPTVFSNPEFLPPTKLR Zygro1 RQRVLLITSRGVNYRRHLIQDLYSLLPHSRKEPKLDTKKDLLNEIAELYNCNNILFFEARKDLYLWMSKPNGPTVKFFVQNLHTMEELN--FTGNCLRGSRPILSFDHKFDYQLIKELLLHNFGVPRKTKPFFDHVMSFSIVDD-KVWVRTFEISHSLVEIGPRFVMTVILVLEGSFGGPKIYENKQYVSPNFVR [Cluster1741.fasta_al_trimmed; alignment length = 156] Allma1 CSVVGSSLFLLHEAIVSNHASTLDDPI-IWG-ALPFSNKLRWTLGAQEICYKNSYFFTAGKTVPIVRGGVYQPAMDFATERLGKGDWVHIFPEG-KV-HQMLPFRWGVGRLILDPLLLPIYHRGLARIHL-PLDISVGDPIHRQWVQVEHAMESLQ Ashgo11 MATIASKAFLLENALIMNHMSVVDDPF-LWA-ALPWRDQMRWCLGAQNVCFQNAAFFSLGRVLSTERFGPFQGSIEASIRLLSPDSWVHVFPEG-FV-LQMRYFKWGITRMVLEPIIVPIFATGFEKIAGAEINVTIGDTVLRSRVILREHVAAIR Aspfu1 FGVAA-RSFLFLELLIAWRTSIMDDPI-MWG-AIPLRSNKRWGFGSHDICYQSALFFTMGQVLPTHRLGLAQPAVTQAIRLLSKGSWVHIFPEG-KI-HQMRYFKWGVARLILEPDIVPIWLEGFDQVMGKDISITFGKKVLRKEVKVRDLVLEVR Aurde31 CAAVGSKAFLLLKALVSNHVSVLDDPL-MWG-VLPAQRRMRWTLGASDILFTRSAFFRSGQVVETFRGGIRQAAIDNAVKQLDRGDWIHLFPEG-KV-NQLLRFKWGIGRMLMDPVVIPMWLTGFDQVMRKDITITFGEPTHRVQVIVQEEVEKLG Batde5 -------MWLYLELSACNHSATLDDPI-LFG-LLPWSKNMRWSLGAKEICFTNSWFFTVGQVLPIIRGGIYQPAMNQAVNLLDNNRWVHIFPEG-RV-NQMLRFKWGIARLVMDPLVLPFYHTGMQHMV-KKIVLAFGKPIQRIRI-------RIQ Botbo1 LPTIGSK--LLLHALVSNHISVVDDPL-SWG-VLPLSDKVRWTLGAHDIMFTNSTFFRAGQVIETFRGGVHQPAIDEAVRKLEAGKWLHIFPEG-KV-NQLIRFKWGIGRILMDPTVIPMWISGFDKIMGKRVSITFGDPLVRIEVCLQEEVERLG Botci1 MGVTGTRFFYFKATLVSNHVSVLDDPL-IWG-----------------------------------------------------------------------------------PEIVPIFIDGNQDIMGKNIRIAFGESILREEVRVRQEVLKVR Caeel MSLVTSKLMFFVKILVSNHRSNIDDPL-MWC-ILKFRDRNRYTLAAHNICFTKTTMFSLGRCVPCVRGGVYQKGMDFCVDMLNDNKWVHIFPEG-KVCTLPLRFKWGIGRLVMDPVILPVWCKEMEKVWGNTVTVHIGEPFMRKIIEVQTRMYQLG Canalb1 LFMITSKIILLDNALVMNHMSVVDDPA-FYA-SLPWRDTIRWGFGAHNICFSNSWFFNLGKILGTKRFGPFQGSLDAAIRILSPDSWFHVFPEG-FV-LQMRYFKWGVSRLILEPIVVPLFSFGFEKVAGAEIHVCIGDPILRSDLYLREKVLEIR Cangl LFTYGSRMILLENAMIMNHMSMVDDPF-VWA-TFPIRDRFRWCLGAENICFQNSYFFSLGKTLSTRRFGPFQDSIDATVRLFSTDPWVHIYPEG-FV-LQMRYFRWGVARTILEPIIVPIFSTGFEKIAGSKIKVTIGEEILRSRLELREHVAKIR Capow VGAVGSILMLLRHALIANHVSCLDEPL-IWG-TLNFAHRMRWSVGASDICFTNSFFFGAGQTLPIVRGGVYQPCMDFAVELLNAGRWIHIFPEG-KV-VQMIPFKWGVGQLIVRPVVVPIYHRGLEDVLFKRVDVLYGEPIMRKAVLLEARMHELK Catan2 ----------------------VDDPV-MWG-LLKNRDDLRWTLGAQELCFQNSWFFTCGKAIPIIRGGVYQVAMDYAVDRLNHGNWVHIFPEG-RV-HQMLPFKWGVGRLIIDPLVVPIYHQGFAKMHASALHVTIGDAIHRQWIQLQERMAEMQ Cioin VASVSSKFWFLHKAVVSNHHCCVDDAL-LCA-ALPWSNSFRWTLGAKDICFTKNYFFGMGKIIPLGRGGVFQRGMDFAIDRLNNNEWIHIFPEG-RV-NMWIRFKWGVGRLINDPTVLPFYHVGSDTVLRKKVTVLIGDPLIRRVLFLQEEIEKLR CocheC53 MGAVGCKGFLFLQLLVSNHISVMDDPI-LWG-ILPLSDNLRWGLGSYDLCFTNSTFFTFGQVLPTHRSGLFQPTITQAIRLLSRGAWVHIFPEG-MI-HQMRYFKWGVSRLILEPDVVPIFVEGFDNIMFQNVRVTFGEKLIRKECRVRQAVVAVR Coere1 IGATSMSMVLLTDVVVANHESLMDDPV-IWG-AMPAREYMRWTLGAQELTYKNNAFFALGQTIPTVRGGIYQLAVEIGLRKLNQNKWVHVFPES-KI-NQLLRFKWGVSRMIMEPIVIPMFFSGMREVMERVFYIRAGDFIVRIHIQLWDAVNKLK Conco1 ----------LLNLVVQNHASTFEDPL-LWG-MLPTRDKMRWSLAAREILFTSSKFFEYGHIIPVNRGGVYQESITKAIEVINRGGWVNIYPEG-KV-NQLLPFKWGVGRIILEPIIIPMYHSGK------------------------------- Conpu1 IAAVGCKAFLLLNALVANHISVLDDPV-TWG-ILPSSKRIRWSLGAADIMFTNSAFFRKGQVFETFRGGIFQPAVDGAIRQLDSGGWVHLFGEG-KV-NQLPRFKWGVGHILMEPIIVPMWLTGFDKLMNVELGVAFGESLARSNIVVQQSVERLG Copci VASVGCKSFLLLDAL--------DRGL-V----------------------TESSFFRLGQTLETFRGGIYQESVNTAIQKLNEGSWVHLFGEG-KV-NQIPRFKWGVGRIVMEPVVIPMWLSGYDKLMGVRLSVTFGEPISR--LLIHNHVESLG Croqu1 MASVMFKPFLLLEAVISNHISTLDDPM-TWG-IMPFNSSVRWTLGASDILFKNAPLFNSGQVIETFRGGIHQLAIDTAIHKLDHAQWVHVFPEG-RV-NQLLQFKWGVSRLALEPIILPIYLQGFERVM-QSIKISIGSPVIRSELALREELVKLG CryneH991 LSTIGSRSFLLLDALICNHNSVVDDPM-MWS-LLPLSRNNRWTLGASDIMFTNSKFFNLGQVIETHRGGIFQEAIDRAVKLLQEGNWIHIFPEG-KV-NQLLRFKWGVGRIVMDPEIIPMWIS------------------VRIKIALQEGMRKLG Crypa2 MGLTTSKGFLFVELLVSNHVSVMDDPL-IWG-VLPLRWTLRWGLGAHDICFKNATFFTLGQVVPIHRSGLFQPSMTQAIRLLSAYAWVHVFPEG-LV-HQMRYFKWGVSRLILEPDVVPMFIDGTCEVMGKDVRVAFGDKLIRIEVRVRDEVVKLR Debha1 LFMILSKLFLLDRALMMNHMSVVDDPT-FYA-ALPFRETIRWGFGAHNVCFSNSWFFNLGKILGTRRFGPFQGSLDAAIRILSPDSWFHVFPEG-FV-LQMRYFKWGISRLILEPVVVPIFTYGFEKVAGAEIHINIGDPILRSDLELREAVLAIR Dekbr2 NTVVGSKIVLLDQAMLMNHMSTCDDPF-IWA-CLPWRDDIRWGMAASNVCFTSSRFFSMGKILSCERFGPFQPASDACVRILSPDSLLHVFPEG-FV-CQMRFFRWGTARMILEPTIVPIFSDGFEKIKGGKVTVNIGKPLLRSKVYLREQVSKLR Dicdi FTLVGCKFWILVNEIIANHSSNLDDPL-LWG-VLPNRSKQRWTLGASNILFTNSKFFSLGKCIKIVRGGIYQDGMNESIDRLSEGQWLHIFPEG-RI-SQLLYFKWGLGRLVGEPLVVPIYHQGMEKSMGINLDIKVGDNIFYKTIHIEDEYQKII Dmel VSAVGSKVVLLIQLIVSNHYSCFDDPG-LWG-CLPLGYKIRWSMAAHDICFTNSLFFMFGKCIPVVRGGVYQDAINLCIEKAALGHWIHVFPEG-KV-NMELRLKWGVGRIIYEPIILPMWHEGMDDLL-KQVTLNVGQPLARKLIKIQEAFRDLR Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba RATLGSVL--IGEYLVSNHRSVFDDPL-TWSSVLPMRSSYRWTLGAQELCFLNGTFFGLGRIIPVLRGGYRQPGLGLAVDIIN-GAWLHLFPEA-YV-NQPLR--WGVGRCIMEPVVIPIWHEGFQLILWNQLDIAVGRPIARKRAIVEEQVRVLA Fomme1 IGTVGCKAFLLLNALVANHISTLDDPL-IWG-ALPARRDMRWALGASDIMFTNSAFFRKGHVLETFRGGVFQPAVDTAIAKLDKGEWIHLFGEG-KV-NQLPRFKWGAGRILMEPVIIPMWISGFENVMRQSLSITFAPPLVQEALVLQRAVEQLG Fusgr1 MGAVGSRGFMLLGVLVCNHVAVLDDPL-IWGAILPLRVNMRWGLGAHDICFKNSTFFSLGQVLPTHRLGLYQPTMAQAIKLLS--AWVHVFPEA-CC-HQLRYFKWGVSRLILEPEFIPMFVHGTQQIMGKTVRIVIGEPTLRISVRVRDEVEKLR Galma1 VTAVCCKAFLLKDALVCNHISTLDDPM-TWG-VLPARRTTRWALGASEVIFTNSAFFSLGQTLETFRGGIYQPAVDTAIQKLNEGRWVHLYSES-KV-NQLPRLKWGVGRILMEPVVIPMWISGFDQLMGARLTVTFGEPVVRKEVVIHRHVEGLG Ganpr1 -----KTPFLFSLLVFSNHVSTLDDPL-MWG-SLPFSRLARWTPAAHELCFNTAFFFGGGQCIPTVRGGIWQPGMDTTLEKMKMGAWVHIFPEG-RV-NQLARFKWGVGRLLLEPIVVPIFTRGTEQVLGQDILVAFGEQIRRSSVVLRHVLRDLG Gloin1 ITSCVCKFFLFLKELVANHLSTVDDPL-IWG-SLPFGYRVRWTLGAQEICFSTSKFFSLGQVVPTVRGGIYQPAMNFALDRLNEGKWVHIFPEG-KI-NQLLRFKWGIGRLLMEPIVVPIWHKGLEEIMGKKIIIVYGNPITRISITVFRAMDELQ Hisca1 HGVFSGSPDIITEMMALMHLSPMDDPL-MWG-TIPLLSNRRWAFGSHDICFSNSAFFTLGQVLPTHRSGLFQPTMTQAIRLLSRGSWIHIFPEG-KV-HQMRYFKWGVSRLILEPDVVPMWIEGTDQVMNKNISVTFGDPVLRIECRIRELVLAVR Klula1 LLAVGSKFMLLQEAVVMNHMSVVDDPF-IWG-VFPWSDQIRWCLGAHNVCFQNATFFSLGKVLSTERFGPFQGSIDASIRLLSPDSWIHVYPEG-FV-LQMRYFRWGITRLILEPIVVPMFSTGFEKIAGAEINVTIGNPILRSRLELRAHVAKIR Lacbi2 VTSVGCKAAILDTALVSNHISTVDDPL-VWA-ALPLRTTTRWTLGASDVMFTNSTFFRLGQTLETFRGGVYQPSVDAAIQKLSDGQWIHLFSEG-KI-NQLPRFKWGVGRILMEPVIIPMWLTGFDRLMGVELTITFGDPIARVAVLIHQRVEELG Lenti61 VSAVGSKALLLLKALMSNHISTLDDPV-VWG-VLPARRRTRWTLGASDIMFTNSTFFRYGQVVETFRGGIFQPAIDTAIEKLNRGEWIHLFGEG-KV-NQLLRFKWGIGRIMMEPVIIPMWLTGFDKLMGAALSITFGKPVVRSAVVIQREVEALG Malgl1 IPSVASRAFLFLHILYANHISVLDEPI-MWG-ALPSSRTVRWSLGASDIIFKNRWFFRQGQTLEVFRDGIYQDAINQAIQHIGRGAWIHIFPEG-KV-NLMRRFKWGISRLILEPYVVPVWLMGFDQIMGADICVVFGDPIIRSHLYLRTNLAHVG Mellp23 MASVMFKPFLLLEVIISNHISTLDDPM-AWG-IMPYRNSVRWTLGASDILFTNAPLFQSGQVIETFRGGIHQPAVDTAIYKLNKAQWVHIFPEG-RV-NQLLRFKWGVSRLVLEPIILPIYLKGFENVM-QSLKVFIGPPIIRIELQLRDSLARVG Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr FTLFGTKLLY--EHMVSNHLSNLDDPG-MW-GFLPI--------------------------------GVYQRGVDYAIELVNRG-WVHIFPEG-KI-FQPRRIKWGVGRILLEPLLMSIHISGFERLRGQDLKINLG-PIARKYLVVQ------- Morel2 MSGVASKIFMFLKILVTNHTSTADDPL-LWG-ALPWRRTIRYALGAQELCYPNGHFFRFGQIVPIIRGGIYQPAIDKSINLLRTGRWVHIFPEG-KI-NQLIRLKWGVGRILMEPIVVPIYHLGMEDILGMPLTIVFGEPIARVRMRVFDALEELK Mucci2 ----------FQSIIVSNHESVLDDPF-LWG-VLPLKHKMRWVLGAADICYTSSYFFVFGQTIPTIRGGIYQPGIDFAIDKVNKRGWIHIYPEA-KV-VQMIRFKWGVGRILMDPLVIPIWHKGMHLAK-KPITLVFGDPVTRVRLRLYKAIEDLQ Mydma ISAVGGKIL-------------------VAT-IMDLKRKMRWSMAAKEICFATSYVSHHGKLIPIERGGVYQDGVNYAIQKLNAGDWVHVFPEG-KI-T-IVRLKWGVGRMINEPIILPFWHVGMQEFLKKKITVLFGDPIARIQLRIQDAFRQLR Neucr2 MGLTGSRTFLFKQLLVSNHISVLDDPV-VWG-VLPLSNNLRWTLAAHDICFANSAFFTAGQVLPCHRLGLFQPSLTQAIRLLSSQSWVHVFPEG-LV-HQLRYFKWGVARLILEPDVVPMFIDGTQHVMGKKIRVAFGEVVIRIECRMREQVLKVR Orpsp11 -----YKNFLFPDRLYCNHLTVLDDPI-IWG------ESFRYTIGAKELCSGKNDFFNAARIITVIRGGVYQKELDKAVDIVHNGEWLHIFPEG-KI-HPINEFKWGVGRFIMEPIVIPIYIYDLDNVFREKYIVTYGNPIIRSQFILREELISLR Pench1 WGVAG-RGFLFTELLVSNHISVMDDPL-VWG-ILPAR-NKRWSFGSYDICYQTSLFFTMGQVLPTHRSGLAQPAITEAIRLLSKGSWVHIFPEG-KI-HQMRYFKWGIARLILEPDVVPMWIEGFDDVMGKRVSVTFGSKVLRKEVKIRNLVLDVR Phybl2 MGGVGGKFFITLDIIVSNHASVWDDPF-LWG-VLPTKDKMRWVLGAADICYTSSLFFSLGQGIPTIRGGVYQPAIDFAIHKMDQHQWIHIFPEA-RV-NQLIRFKWGIGRIVMEPIIIP-----------NPITVVFGEPIARIRIIVYEALKKLK Picst3 LMMLLLKVLLLDKALVMNHMSVVDDPT-FFA-ALPMRDDIRWGFGAHNVCFSTSWFFNLGKVLGTKRFGPYQGSVDAAIRILSPDSWFHVFPEG-FV-LQMRYFKWGISRLILEPVVVPVFSFGFEKIAGAEVHISIGEEFLRSDLELRNSVLNIR Plicr1 ATTIGCKAFLLLDALVANHTSVLDDPV-TWG-VLPAHRMTRWALGASDVMFTNSAFFRNGQVLETFRGGVYQPAVDTAIKKLNNGAWVHLFGEG-KI-HQLPRFKWGVGRIIMEPLVIPMWLTGFDTLMGAKLSVTFGDPLIRSDVILHRAVEALG Polpo INLTKGNVVLQINQLVSNHIANLDDPI-MWG-NLGWDQNMRWTLGASNILYTNSYFFNLGKCVKTIRGGIYQEAIDFAIDRLSEGQWVH----------------WGVGRMVAEPLILPVYHRGLEQSMGKHLEFFVGQPFIRLKLQFDNILALLK Pucgr2 IASVMFKPLILLEILRARHDRKLDDPM-VWG-IMPFSSKVRWTLGAADILFTNAPLFQNGQVIKTVRGGIYQPALDLAIEKLDNSQWVHVFPEG-KV-NQLLRFKWGISRLVM----------------NQSLSIKLSPPIIRIELFLHSQLLAVR Punst1 VTTIGCKAVLFLQILASNHISTLDDPL-AWG-VLPTRRTIRWSLGAHDIMFTNSAFFRKGQVLETFRGGIYQPAVDTAIKKLDQGHWVHLFGEG-GV-NQLRRFKWGVGRIMMEPIVVPIWLTGFDRLMGQDLSVTFGQPIVRAEVIVQDAVEELG Rhior3 MGMTGAKGFLFMAILVSNHKSTLDDPC-LWG-VLPIQKKMRWVLGAADICYTSSYFFAFGQAIPTIRGGIYQPGVDYAIHILNQGAWVHMYPEA-KV-NQMIRFKWGIGRMVMDPIVIPILASRAC----DPTIL-----L--------------- Rhoto1 PLVVGSKLFLFLERLVSNHISVVDEPF-MWG-CLPLRQTLRWTLGASDVMFNGRWFFTKGQVIETFRGGIYQKAIDEATKKLDEGQWVHIFPEG-RI-KQLRRFKWGISRMLMEPLIIPVWIKGFEQVMGKNVTILLGEPLMRSEMVMRQGLMQLG Rozal11 ----------LLDAIFSNHNSTIDDPT-VWA-ALPLTDKLRFALGARELTYMNSWFFSRGQVIPIERGGIFQKGMDDALKILNEGGWVHIYPE---V-FQIHPLRWGISRLILEPILVPIIHHGMEHVYRKTVVCRFGKPLKRIEIAIQKEMQVLY Sacce1 LLTFGSKLLLLETALVMNHMSMVDDPL-VWA-TLPYKDNIRWSLGAHNICFQNANFFSLGQVLSTERFGPFQGSIDASIRLLSPDSWVHVYPEG-FV-LQMRYFKWGITRMILEPIVVPIFATGFEKIAGSEINVTIGDPLLRSRLELRAHVAEIR Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 VAAVGCKAFLLQAALVSNHISTLDDPV-TWG-VLPTPHFMRWTLGASDIMFTNSWFFRNGQVLETFRGGIYQPSIDTAIAKLDQGEWIHLFGEG-KV-NQLPRFRWGVGRILQEPIIIPMWLTGFNKLMGQKLSVTFGAPLNRSEIILQDAVQELG Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma MGLTGSRTFLFKQLLVSNHISVLDDPV-VWG-VLPFSNNLRWTLAAHDICFANSAFFTAGQVLPCHRLGLFQPALTQAIRLLSAQSWVHVFPEG-LV-HQLRYFKWGVARLILEPDVVPMFIDGTQQVMGKKIRVAFGEVVIRIECRMREQVLKVR Sphar VALTGTAYVLFLMALCSNHLATVDEPL-LFSSLQKFTYKMRWGLCAQEICFEQATYFGAGKSLPIVRGGVMAPNFKKACDKVRFGEWVHIFPEG-RV-HQ---LKWGVGRLVANPLVVPVYQYGIQNTIGLKFVVKIGDPIVVDRVRLLEMEDEVK Spipu1 RSSVGAKLFLLLKTIVGNHLSVLDDPM-LWG-ILPWKHRMRWSLGAKEICFGNAWFFGSGRVIPIVRGGIYQPAMDLAIQKLNQNGWVHIFSEG-RV-NQMLPFRWGIARLIMEPIVVPFWHKGLESVM-KELILAFGEPIARIRLYIFQQTVQVQ Sporo1 -------------------------------------------------------FFRKGQVIETFRGGIYQDAVDLASRKLDDGNWVHIFPEG-KI-KQLRRFKWGVSRILMEPLIVPVWIKGFEQVMNKDITILYGEPIARKE----KGVCRCG Stehi1 VATIGCKAFLLLDALVSNHISTLDDPV-TWG-IMPTQRLTRWSLGAHDIMFTNSTFFRNGQVLETFRGGVYQPSVDTAISKLSQGDWVHLFGEG-RV-CQLRRFKWGIGRIIMEPMIIPMWITGFDKLMPVPISITFGTPIIRKRVVVQDAVERLG Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr VGVLGSRLFMLVAAVVSNHVSIYDDPFTVAA-AVPWMHKLRSTLCATNRCFFHGKILSLGRVLPVQRGGMYQPYMDDVVARV-AAEWIHLFPEGTRT-ALMLPLRPGIGRLVADPVVLPLVHVGMH-TLGQAVTIVVGEPVLYNAIRLQRVMHNLL Treme1 ISAVGFKALILLDALVCNHNSVLDDPG-MWA-LMPLSQHTRWTLGASDIMFTNSKFFTLGQVIETYRGGVFQPAVDQAVKLLQSGEWVHIFPEG-RV-NQLFRFKWGVGRIIMDPEIIPMWVSRFDTVMGGKLSVTIGQPIIRIRIILQEQVEKLG Trire2 MGSVGSRAFLLLGVLVCNHVSVLDDPL-IWG-ILPLRENLRWGLGAHDICFKNSAFFSYGQVLPTHRLGLYQPTITQAIKLLS--AWVHIFPEA-CC-HQLRYFKWGVSRLILEPEFVPMFIHGTQNIMGQRIRIMIGQPTLRVDVAVRDEIQKLR Umbra1 VGSVGSKLFLFQELLVANHASVIDDPI-LWG-ILPVREKMRWVLGAAEICFTNSLFFGMGQVIPTVRGGIYQPAVDFAIHKANQNKWLHVFPEA-RV-NQLIRFKWGVGRMVMEPIVVPMWHTGLSEIR-KPITIAFGDPIARIQIRIFKTLGELR Ustma22 IRAVASRTLLFLSHLYCNHISVLDEPT-IWG-SLPASHTVRWTLGASDIMFTNSKFFRNGQCIETHRGGIHQAAIDESISKLDAGKWIHLFPEG-YV-N-LRRFKWGIARMLIEPVVVPIWITGFDRLMGADVTINFGEPIARSQLLLRHHLGLVG Walse1 MLTVSVKLFYLTKALITNHRAVGEDPL--WPAILPLKKYRRWTLGASDVIFTNRKFFQAGQVLETYRGGVDQPAVYQAAQLLDEAKWVSMFPEG-RI-NVLRPFRWGVGRMLTLPTILPIHLTGFNDVFNARITVDIGDPITRKEIILRKHLDDFG Zygro1 LATIGSKLILLERAIVMNHMSCVDDPF-LWA-VFPWRDTIRWCLGARNVCFQNGTFFSLGKVLSTERFSPFQGSIDAAVRLLSPDAWMHVYPEG-FV-LQMRYFKWGVSRMILEPIVVPIFTTGFEKVAGAEINVTIGDPILRSAVELRNHIAKIR [Cluster1753.fasta_al_trimmed; alignment length = 160] Allma1 HAIQVSQRGNPVLIR-SVAWEFA-EADYVVARTAGVLFL-SIKYHRLHPEYIHARIKGLFDLRVMLVLVDVSVRELTRIAVVNNMTMVLAWSKEECARYLEMYKTMEYRPPDYMSRLLTQIKGVNRTDVLTLSANFGTFERIVEATCPGIGAKKAFRQPF Ashgo11 RTILVSQKGNPLLLA-STNWTYVKSYDYQV-QGRKVVFL-SLKYHKLRPEYIDQKLRPFTQGNILLCVVDIILKELNKTTMFNGFTMLLAFNFEQAAKYLVFLNK------------------------------------------------------- Aspfu1 SAILVSQKGNPILIK-LLPWEYA-DADYVVGATTCALFL-SLKYHRLHPEYIYSRIKALYMLRIILVMVDISLKELSKTSIINNYTLMLCWSAPEAAHYLELYKSSENAQPSYKESLVTTPRSINKSDAASLISTFGSLQNAINAQVPGWGEKKAVREDF Aurde31 SSILVNQRGNPVLIR-NVAKEWS-DPDFQMGRTTCALFL-SLKYHRLHPEYIHTRIQRLYTLRILLIHCDISIRELTKVCLINNMTIIVAWSPEECGLYLSTFKVYEHKPPDHMSILLTSIRSVNKTDVTTLKTTFGSFAGIAKATCPGIGQTKAFEHPF Batde5 RAVIVNQEGNPVLIK-NVPWEYG-EADYQVGKTTGVIFL-SLKYHRLYPEYIDTRLRQIFYLRILICVVDVSIKELTRTCIFGKTTMILAWSRQEAGRYIETLKSYENKPPDYFSKLVTAIKSVNKTDAMTLASNIGSFKDIAHATLPGFGEQKAFTTVF Botbo1 ------SHGNTQILI---------T---------------NLKYHRLHPEYIHQRIEKIYNLRILLVMCDVPIRELTKTCLINNLTIMVAWTAEEAAAYLQMYKAYEHKSPDYSSLLLTTIKGVNKTDVMTLRTNFGSMASIAAATCPGLGGVKAFEKPF Botci1 SSIQVSQKGNPILLK-SFPWEYS-DADYVLGTTTCALFL-SLKYHRLHPEYIYNRIKGLYNLRVLLTMVDISLKELSKTSLVNNVTVILCWSALEAARYLELYKSYEHANASYGDKMITVPRSINKRDAVALVDAFGSIRGAINARVDGWGEKKVVDEPF Caeel GALVVNQEGNPVLVR-NVRYEWG-DPDFECGPTFGVVYL-SFKYHKQHPEYVYTRINGNYRNKVLLGYCNMVLRELNMICFREAWTFVVVYTVEEAAEYIELFKTTQKKEIGGDSSMLTAARSITKTDADRLLFHFGTLQAISTASCPGVGPIKAIISPN Canalb1 SDILVSQEGNPLLMQ-ATPWSFDKSSDYYINPKFQIIFL-TLKYHKLHPEHIWNRWKKLDALRVLLVVVDVLLRKLSDFCIKHDLSLVLAWSYEEAANYIALCKQLDKAPLDYNSSVFTGIKSVNKTDVSNLLANCKSVKEIVLQSIPGLGAKKVFSEPF Cangl KTVLVSQKENPLLLK-NTNWRYSKPYDYKV-KNRSILFL-TLSYHKLYVDYIERRMLPLNNDNILIFVVDDILTTITKICLFNGFTLLLAFNFQQAAKYLEGLNSF------------------------------------------------------ Capow TCLQVNQEHNPMLISGTVPYEIV-EPDFVMGRSVCALYL-SLRYHLLHPEYLWQRMRELYELRILLILVDIVLRELTTVTVRFKFTVVLAWSEDEAARYLETYKMYESKPADFLSRVLTSIKSVNKTDVITLLSTFGSLKNIANATCPGIGEHKAFHQPF Catan2 SAILVNQRGNPVLIL-TVPWEYS-DADYV--------------YHRLHPEYIVQRIRGIFELRVLLVLVDVTVREVNGVCIANDLTLILAANNEECAKYLEMYKSMEHRPADYSSRLLTQIKGVNPT-------------------CPGIGEKKAFRKPF Cioin NALIVNQKGNPILIH-GVTWRYA-DVDYIMGPSTCC---------------------------------------------------------------------------------------------------------------------------- CocheC53 SSILVSQKGNPILVR-AVAWEYS-DPDYVVGATTCALFL-SLKYHRLHPEYIYNRIRDLYTLRILLTMVDIPLRELSKTSLVNNVTVMLCWSAQEAGRYLELFKTFENAAPSYAENMITVPRSINKTDAVGLVSNFGSIRTAINAAIAGWGDKKAVREPF Coere1 --VKVNQRGNPLLIR-NVRWTYSRDSDFEVGRNSSLYYL-SIKYHRLHPEYISKRIEKSYK-KILLLFVDTPLREINRFALLNDITLLLAWSLDEAGRYIESLKVLEYRP-NFMAKFLTSIRSVNKTDVLTLANNFKSFKGISKSTCPGVGDLKAFNEPF Conco1 -------RGNPILVR-AVPWEYK-DPDYVVGKTTCVLYL-SLKYHKLYPDYIFQRVQKLYQLRIILCRVDIYLLELTKLTMNANLTLLLSWNDEEAG--------------------------------------------------------------- Conpu1 NNIIINQRLNPLLIR-NVGKQFG-EPDFQVGRTTCVLYL-SLKYHRLHPEYIHARIEKLFNLRILLIMCDVPIRELTKTCLINNITIIVAWSLDEAGHYLSTFKQFEHKPPDYDSVLLTSINKVNKTDVETLRTSVGSFADIARTPLPGFGQVKALERPF Copci NNIIINQRGNPVLIR-NVGKEFG-DADYQVGRTTGVLWL-SLKYHRLHPEYIHTRIEKLYGLRLLLILCDVHIRELTRVCLINNITIIVAFSLDEAGHYLSTFKQFEFKSPDHHSILLTSISKVNKTDVETLRTAFGSFAGISRATLPGFGQVKAFEKPF Croqu1 -----MIKGNPILIQ-SVPWEYG-DCDYQVGLTTGLLFL-SLRYHKLHPDYLHTRINKLYNLRILLVLCDVSIREITKVTVINRLTIFIAWSNAEAARYIQLFKSFERKPPTYLTQLLTTVNGLNKTDVLTLASSFGSFRNLTEASCPGLGEKKSFNSTF CryneH991 SSIIYNQRRNPVLIR-NVGIEVG-DADYQVGAHNGVLFL-SLKYHRLHPEYIHQRIEKLYNFRVILLLCDVSLRELTKIAIINEFTIFVAWSNEEVAQYLVTFKQFEHKSATYHDQLLTSGKKVNKTDADNLAAEFGSFEAISRKSVKGLGATKAFTKPF Crypa2 STILVSQKGNPVLLK-SVAWEYS-DADYGLGLTTCALFL-SLKYHRLHPEYIYTRIRNLYNLRVLLAMVDISLRELSKTSLVNNVTLILCWSAAEAARYLELYKSYEHASFGYAEKLVTVPRAVNKADAVALVSTFGSLRAAVNADISGWGEKKAVEEPF Debha1 SSVQVSQKGNPLLMK-SIPWSYNGSSDYYINPTLQILFL-SLKYHKLHPEYIWQRLKKLRVLRLLLVVVDIILRKLLNFCIKQDLSLVLAWSFEEAGNYIGFCKQYELSSSEYQACVLTGIRSINKTDSVKLLANCGSVKNIVLQSIQGLGSRKVFLEPF Dekbr2 SSIQVNQNGNPLLLT-SVSYKFNGQVDYLVNSRCFAIFL-SVKYHKLHPEYIYHKIQKIGMLRLMLVSVDVSMRELNKSCLLNNSTLIAAWSFEQCADYLTGLKQCEMNTASYYKRVLTTIKAINKTDAINLVSHFGSLKELCQKAIPGMGQRKVINDPF Dicdi DKIYANQRGSLMMSK-NIIIEYS-EPDFILNSNTLVFYLPSLKTHRDNPNLIQDRIKGLFTLRILLVFADLFINELNLIAIKLQFTLIVCWSQIEAAKYLEAYKTFNNRAPGGKSKNLTSIKSVNKTDATTLLKNFQTMQQIFTCQLPGFGPVKTINQPF Dmel HCVLVHQRGNPILIL-NVPLEFRDDPDYVVGRTSCVLYL-SLKYHNLNPDYICQRLKALYELRVLLVQVDTALKSLTRISLLADLTMMLAWNAEEAGKIIETYKQFEKRPPNPHQKLLTNIKPVNKTDAAALLHTFGNLGNIINASVMGLGPRKTLQEPF Enthi YVIKANQKKNYKLIRKRVEYDPG--GDFIVGNMTKIFYL-TYKYHSTNIKYLEECIVPLEYLNIVLFVIDCIIQDVNIKLFKKKCTLIIAQSYSDAAHYIEEFSVVENSQN---TQILSMIKGINSQNAYDLLMKFNTLKRLGVVDSKNIGPKKVFHSPI Falba DSIIADQRGNPALRRTRDPQDLPTDGDFILGRTACAIFL-CTSYHRQFPAYVYEQAKRLFDLRLLLVLCDSILTELTRLAVNYRLTILLAETPDEVARILVTTRRTTLAMAPHAPDILLTVRGINRTDAQRLRRTFPTVQALAAASVPGIGREKAFREPL Fomme1 -------RLNPLLVR-NVSKEFG-DPDFQLGRTTCALYL-SLRYHRLHPEYIHQRIQRLFTLRLLILMCDVPIRELTKICLINNITIIVCWSNEEAGMYLATYKLFEHRPPEYNAMLLTSINKVNKTDVETLRTSFGSFSKIAHTTLPGFGQVKAFDKPF Fusgr1 STILVSQRGNPVLIR-SMPWEYS-DSDYVLGLGTCALFL-SLKYHRLHPEYIYTRIRNLYNLRILLTMVDISLKELSKTSLVNNVTLILCWSAAEAARYIELYKSYENASFSYGEKLVTVPRSLNKSDAVAVVSNFGSLRNAINADLNGWGGVKAVEEPF Galma1 NNIVISQRGNPVLIR-NVGKEFG-DADYQVGRTTGVLFL-SLKYHRLHPEYIHTRIEKLYNLRILLILCDIPVRELTKACLINNITVMVAFSFDEVGQYLTTYKQFEFKPPDYHSILLTTISKVNKTDVETLRTSFGSFANISRATLPGFGQVKTFEKPF Ganpr1 ATLLVSQRGNPLLLR-NTPWAYA--ADYQVGASAGVLYL-SLKYHRLHPEYVTGRVEGIYGTRVLLVLVDVHLPSLTSLCLFNALSLILATTLPEAARYLETFKAYEHKPPEWFERVVTSVKSVNARDAETLVEAFGSLKAIVAATLPGIGQAKAFRQSF Gloin1 NSIIVNQRGNPVLIR-NVPWEFG-DPDYVVGQTTCALFL-SLRYHRLHPEYIYNRMDKLYVLRILLVLVDTSIRELTKICVINNFTMILSWSSEEAGRYLETYKVFEHKPPDYLSKLMTQIRFVNKTDVVTLASTFGSLKNIMEATCPGIGEQKAFEQPF Hisca1 SSILVSQRGNPILVR-HVPWEYA-DADYIVGSTTCVLFL-SLKYYRLHPEYIYSRIKGLYNLRILLTLIDISLRELSKTSLVNNLTLILCWSAAEAGHYLELFKSCEHAQPSYNESLITTPRSINKSDAASLISTFGSLQAAVNAKVPGWGEKKAVRDDF Klula1 KTMFVSQTGNPLLLV-NVNWRYVKSYDYQI-RGRNVIFL-SLKYHKLHPEYIGKKLLPFTEGNVLLCVVDVILRELNKVCMFQGFTILLAFTFEQAGKYLTFMNK------------------------------------------------------- Lacbi2 NNIIISQRGNQVLIR-NVGQEFG-DADYQVGRTTGVLFL-SLRYHRLHPEYIHARIERLYNLRILLILCDISIRELTKVCLINNVTVIVSFSFDEAGHYLSTFKQFEHKPPDYHSTLLTSIGKVNKTDVETLRTSFGSFADISRATLPGFGQVKVFDKPF Lenti61 NNIVVNQRGNPVLIR-NVGKEFG-DADYQVGRTTGVLFL-SLRYHRLHPEYIHQRIERLYNLRILLLMCDVPIRELTKICLINEITVMVAWNAEEAGYYLSTYKQFEHKPPDYHSMLLTSISKVNKTDVETLRTSFGSFAAVSRASLPGFGQVKAFNKPF Malgl1 SSILVNQRGNPVLIK-GVAWEYA-DPDYQVGISNGVLFL-SLRYHRLHPEYIHMRIQRLYTLRILLVVCDVAIRELTKVALVNQIVMIVAWSAEEAAHYLEIYKAFEQKPPDSLSVLLTNVRGINKTDVLTLSTRYHTFRDIVHESLPGMGDTKAFRQPF Mellp23 ------QKGNPILLQ-SVPWEHG-DCDYQVGLTTGLLFL-SLRYHKLHPEYIHTRIGKLYNLRILLILCDVSIREITKVSVTNQLTVFLAWSNAEAARYIQLFKSFERKPPTYLAQLLTTVNGLNKTDVLTLASSFGSFRNITEASCAGLGEKKSFNSPF Mnele AAVIVSQRGNPLLMR-NVIVTYR-DPDYVLGANTCAIFL-SLKYHRLHPDYIYERLRQLYIVRILLLQVDICIEELTKVALLSSLTLMLAWSPAEAARYLEAFKIYENKPPSYQGHLLTSIRGVNKTDVARLKSEFGTVKDIVQADLPGIGEKKLFRQPF Monbr ----VSQKDNPLILR-NVPFQLV-SPDFIMGKTTCALFL-SLRYHNLHPEYIHARIREVYALRVLLVQVDVVISDLAKLCVMHDYTLIVAGSIREAARYLELYKSFENKSADYLAQLLTTFKTINKTDAVTLLSTFSSLARIAKASCPGLGDKKILDRPF Morel2 AALVVKQRGNPLLIR-NVPYEYG-EPDFVVGATSCVLFL-SIRYHRLHPEYIFSRISSLFVLRVLLVLVDVAIRELTRVAMVNDLTLVCAWSNEEAARYIETYKAYENKAPDYLSKLLTQIPSINKTDIVTLSSTFGSLKNIMDASLPGFGERKAFDQPF Mucci2 NTILVNQQKNPILVH-NVPWEPS-EMDYVVGQTTGVIYL-SLRYHRLYPTYIYDRLNSVYVKRILLVYVDVALREINRIAILSDFTLMLAWSPEEAGRYLETYKAFENKAPEYFAKMLTQIRSLNKTDVLTLLSTFGSLKQVAEAKCPGFGEQKTWKQPF Mydma NAIIVNQRGNPILVH-NIPWEYG-DADYEIGQTACAMFL-SLRYHSLNPDYIHDRLQLLYTLRILLVLVDISLKKLAKISLLANCTLILAWSNEEAGRYLETFKTYENKPPDYVSKMLTTVKSISKADVITLLSNFKSLKNVANASCPGFGPKKALHEPF Neucr2 SSILVSQKGNPVLIK-STAWEYS-DADYVLGTTTCALFL-SLKYHRLHPEYIYTRIRLLYNLRILLTLVDIPLRELSKTSLVNNVTVILCWSAQEAARYLELYKSYEHASATYAEQMVTVPRSVNKTDAIALVSTFGSLRNAIN--VQGWGEKKAVEGSF Orpsp11 NRVLVNQKGNPVLIR-NVAWEYS-DPDFQVGETSCILYL---RY---------------------LLFSHL----------LFNFSFFI----------------------------I------------------------------------------ Pench1 SAILVSQKGNPILIK-LLPWEYA-DADYVVGTTTCAMFL-SLKYHRLHPEYIYSRVKQLYNLRLVLVMVDISLRELSKTSIINNLTLILCWSAPEAAHYLELYKSSENAQPSYKESLVTVPRSINKSDAASLISTFGSLQNAINAQVPGWGEKKAVREDF Phybl2 NTILVSQQDNPLLIR-NVAWEFD-SPDYVVGKTTGVLYL-SLRYHRLHPEYIYERMNKLYVLKVLLVSVDIALRELNCAVITHNFTLMLAWSLEEAGRYLETYKYFENKSTDYQIKMLTNVNTVNKTDATTLLSNFESFEGITKASCPGFGDQKALQQPF Picst3 SEILVNQIGNPLLMR-ITPWRQDNDSDYYISPMLQILFL-SLKYHKLKPEYVWTRLKKLKVLRVLLVVNDVLVRDLSGFCIRNDLSLVIASSFEEAGNYVVQAKKSYDAPVDYNSSVMTGIQRINKTDVSNLLANFKSVKEIILQGIGGLGAAKVFLEPF Plicr1 NNILINQRSNPMLIR-NVGKEFG-DPDFQVGRTTGVLYL-SLKYHRLHPEYIHTRIEKLYNLRILLLMCDIPIRELTKMCMINNITVMVAWTHDEAGLYLSTYKQFEHRPPDFTSRFLTSISKVNKTDVETLRTSIGSFAAIAQCPLPGFGQVKAFERPF Polpo KTLVANLKGNPIFLQ-STTFEFQGGPDFVMSSTSCCLYT-TLKDYRLKPTELIDRSKQLFELRVLVVVVNILLEELSFVCTQINLVLIVAWNVPEAARYIEGFKILDTVSPLDKTLVLTTIKGINKTDATTLISTFGTVKRIFDGSCPGMGQKKVLHQPF Pucgr2 NNIIVNQRGNPVLIK-SVPWEFG-ESDYQLNQTTGSLFL-SLKYHRLHPDYLDTRLKKLYDLKILLCLCDSVLKDITKTCMVNEFTLIVAWSNAEIARYIQLFKSFEKRSPDYMSQLLTTIRGLNKTDVMTLATNFRSFRQIVEASCPGLGEKKAFNSDF Punst1 KNIIVNQRLNPVLIR-NVGKEFG-DSDYQVGRTTGVLFL-SLKYHRLHPEYIHQRIERLYSLRILLLMCDVPIRELTKVCLINNITIIVAWSPEEAGMYLSTFKQFEHRPPDYFSVLLTSISKVNKTDVETLRTSFGSFARIACASLPGFGQVKAFEKPF Rhior3 NTILVSQQKNPVLIR-NVPYEPS-EVDYVVGQTTGVIYL-SLRYHRLYPTYIYDRLNNV--------------------------------------------KHLERDQSE------------------------------------------------ Rhoto1 NSILVNQKGNPVIIR-TVPWEYG-DCDYQVGATAGVLYL-SIRYHLLHPEYIHTRIQDLYNLRIILCQCDAAMKELTKVAIVNGYTLITCWSAQEAGRYLETYKSFERKPPSYMAHMLTSVRGVNKTDVTTLISNFGSFANLVLAELPGLGDKKAFTAPF Rozal11 SSILVNQKGNGLLIR-NVPWEYFDDADYILGDTTGAVFL-SLQFHRLYPEYIFDRMKALFKCKILLCLVDVSMKQITKSCLLYGFTLVCAWSNEEAGRYMETFKAYEKKSADFISQLLTTIKSVNKTD---------SLAGIMNADCSGIGQRKRFQQWF Sacce1 KTVLVNQKENPLLLK-STNWRYVSSYDYLV-RGRSVLFL-TLTYHKLYVDYISRRMQPLNENNILIFIVDDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL------------------------------------------------------- Salro NFVRVDQKGNPVLIR-NVPWQYC-EADFVMGKRTCGLFL-SLRYHLLHPEYIHGRIREVYQVRVLLVLVDVVLMDLTKLCMVHNYTLMLGWSNKEVGRYVETYKAYENKSADYLSQVLTSVRSVNKTDAITLLSAFGSVRGIATASCPGFGDKKVLTQPF Schco3 NNIIVRQRGNPVLIK-HVGKEYG-DADFQVGRTTGVLFL-SLKYHRLHPEYVHSRIEKLYTLRILLILCDVPIRELTKTCLINNITVIVAFSVDEAGHYLATFKQFENRPPDYNSVLLTSISKVNKTDVETLRTSFGSFADIARASLPGFGQVKAFEKPI Schpo1 --ILVNQKGNPLLVR-NVPWEYT-DPDFVMGTGICSLFL-SLKYHHLHPEYIYSRISKLYNLRILLILVDVSIQELVKTSIVNQYTLILAWSSEEAARYLETYKAYENMSPDYLSQVLTSIRGINKSDSLSLLSKFGSLERALVASLEGWGPTKAVQQPF Sorma SSILVSQKGNPVLIK-STAWEYS-DSDYVLGSTTCCLFL-SLKYHRLHPEYIYTRIRALYSLRILLTLVDIPLRELSKTSLVNNVTVILCWSAQEAARYLELYKSYEHASATYAEQMVTVPRSVNKTDAIALVSTFGSLRSAINATVQGWGEKKAVEGGF Sphar NAITVNQKGNPILLQ-HTAYEYG-DPDYHISPHTAIMYL-SMRFHLYRSNYIGAAVRSLYTLRVLLLHIDVALVDLTKLATLNGLTLICAWSPEEAARYIETFKRYENKNSSYLARALTEVNSVNSTDVITLLSAFGSIKDVVAADLPGVGDQKAFRAPF Spipu1 HSIVVNQRGNGVLIK-NVPWEYG-DPDYQVGMTSCALFL-SLKYHRLHPEYVYTRIRQLYLLRILLCLVDISIRDLTRICVYNNITLILAWSQEEAGRYLETFKAYEHKPPDYLSKLLTQVKSVNKTDVLTLASAFGSLQNIMSASCPGFGEQKAFHQPF Sporo1 NSILVNQKGNPVIIR-SVPWEWG-DCDYQVGPTTGVLFL-SIRYHLLHPEYVHTRIADLYSLRIVLVQCDAAMRELTKICIVNNYTLLVAWSAQEVGRYLETYKQFERKPPSYMAHVLTSVRGVNKTDVATLVSNFGSFEKIVNASLPGLGDKKAFTGSF Stehi1 KNIIINQRLNPVLIR-NVGKEFG-DVDFQVGKTTGVLFL-SLRYHRLHPEYIHKRIEVLYNLRILLLLCDIHIRELTKICIINNITMIVAWSPDEAGQYLATFKQFEHRPPEPMAMLLTSISKVNKTDVETLRTTFGSFANISRATLPGFGPKKAFDKPF Tapde11 NAILVNQKGNPVLVR-NVPWEYG-DADFVVGATACAMFL-SLKYHRLHPEYIYNRVRDLYGLRVMLVLCDISLRELAKTCVVNNFALVVAWTAAEAGRYLESFKSLETAPAVYSDQLLTSVRSINKTDAWNLVGTFGTLRAALEASLPGWGPQKAINLPF Thetr RCIVVSQRGNPLLIR-RVPWEYG-SPDFRLGAFTCALFL-SLKYHNLHPEYLGTRIIELYRVRVLLCLVDIALTQLASICLASELTLVLAWSMTEAARYLETLKAYENKGPDYFSRLLTAVRGVNKTDAATLATAFGSVANMLTASVPGLGARKVFNTPF Treme1 ------KRRNPVLIK-NVGIEIG-DADYQVGTHNGVLFL-SLKYHRLHPEYIHQRIEKMYSLRIMLILCDVSLREISKIAIVNDFTVFVAWSNEEVAQYLTTFKAFEHKSATYHDQLLTSGKKVNKTDADNLAAQFGSFANIAKQPVKGLGAAKAFNKPF Trire2 STILVSQRGNPVLIR-SIPWEYS-DADYVLGLTTCALFL-SLKYHRLHPEYIYTRIRNLYNLRILLTLVDISLRELSKTSVVNNVTVMLCWSAAEAARYLELYKSYENANFNYADKLVTVPRSLNKSDAVALVANFGSLKNAINAEISGWGGIKAVDEPF Umbra1 NTILVNQRGNPILVR-NVPWEYD-DADYIVGQTTCVLYL-SLRYHRLHPDYIYDRMGKLFVLRILLVFVDISIRELTKSAIIQNFTIMLAWSHEEAGRYLETYKAFEGKPPDYMAKLLTQVRTVNKTDVLTLRSTFGSLNRIINAPCPGFGEQKAFTQPF Ustma22 NTILVNQRGNPVLMR-NIGWEYA-DPDYQVGLSACVLFL-SIRYHRLHPEYVHTRVQKLYTLRILLVLCDVAIKELTKTCVINKLTLMLAWSAEEAARYLETYKSFELKPPDYLSQVLTQVRGINRTDVITLLSTFGSLKNVVNANCPGFALRKVFTLPF Walse1 NAVLVNQRGNPILVR-NVSWEYT-DPDYVAGSSTGILFL-SLRYHRLHPEYIHTRVERLYQLRILLLMCDVSIKEITKTCLINNITVVIAWSPQQAGHYLSLYLQLDNKPPDYHSMVLTTVKGINKTDVYQLLTRFGSIKNIVKASCPGFGDIKAFISLF Zygro1 KSVLVNQKANPLLLK-NTNWRYVSSYDYLI-KNRSVLFL-TLTYHKLYTEYISRRMLPLSDDNILIFVVDDILTEITKLCMFKGFTLLVAFNFEQAAKYIGYLNC------------------------------------------------------- [Cluster1762.fasta_al_trimmed; alignment length = 219] Allma1 GKFEELHRK-AQFVTT-HHMFDGLKVDIGKGMFQVNHAFHLYTFGAVVAEDAMMHGMIET-DGSLTGRMLQAEADYAGRDYAANVKVVNPSPVDVASYLQSVTPKLALGVEAVLQG-MSFAARYVLTATYLHLTYVHPVSSKVELASEAQMREGVGAVAAKYEFRQS--TFRTQIDTNGRVSSVLEQRM--GP-MAFLLAGEIDHVKGAARFGFGLHME Ashgo11 GTMENLNKEVSRDVLT-QYFFTGLRADLNKAFFQTSHTFSMYAFSALFANDDFMQGNVDN-DLSLSGRMCQLEQDFQGSDFSLNLKTLNPSLSAVGSILQSITPQLAVGIEAVYSA-VSYATRYIFSGQLLTASFWRKVASNVEAGVESTLIEGLTTIGAKYEYRQS--VFRGFINSNGRVGCFLERKI--LPTLSVLFCGEIDHFKSDSKLGCGLQFE Aspfu1 GTVDNIAREVQKEVLS-NFMFSGLRADLTKVFFRVSHAFSMYAFSAMYGTPKFMQGNFGS-DGALAAVLLQIDNDYTGDDFSASIKAFNPSCLDVGSYLQSITPSLALGFEAIWQA-LSYCARYIASAQLFTASYWRKLSERVEAGVDMNLRDGTTSIGAKYDFRAS--TFRAQVDSAGKVSCLLEKRI--AMPISLTFAGEIDQAKQSAKLGLAVSLE Aurde31 GTVENLQKE-VKNTLN-NYIFDGARADLSKTLFQVTHSFALYNFGALFINNSYMQGNVDH-EGNVNARMIQMEHDYQGRDYSVNLRAINPSPTDMGNYLQSVTKNLALGVETLYQN-VSYMVKYIATAQFLMASYWQKLSEKLDVAAELQVRNALATLSAKYELRMS--TFRAQLDSSGKVSALLEQRF--APTFAFLFAGEIDHFKNAAKVGVGVMIE Batde5 GNYESLHKE-VRGVPT-VFMIDGARFELHSHHFQTGHTLSWYQFTSAYSTPTALVGQVDH-EGSVSARMIQLEHDHHDLDWSLNAKCSNANLIDTLSYLQSISKSIALGAELTYQS-LAFAFRYVFTATWFSSTYWRRINQRLEVGSELQLREGMASVGFKVDTVFT--TIRAMVSSHGQVSAVLEEKI--APGISLQLCGEIDYARGSARVGFGFTFE Botbo1 GTTENLTKE-VKTTLT-NFIFDGARADITKGLFQVTHSFSLYNFGAVFANQNFMQGGVDN-EGNMNMRMITLEHDYLGSDYSLNVKAMNPSPLDVGSWLQSITKNLAIGTETLYQS-TSYLAKYIATAQLVQATYWQRLSEKVEVAADLQVRDALATVGAKYDLRMA--TFRAQLDSSGKVSALLEQRF--APTFAFLVAGEIDHFKNAAKVGVGIMIE Botci1 GTVENIAREVQRDVLN-NYTFSGLRADLTKPFFQVSHAFSMYTFGALFGTSKFMQGNMDN-EGQLTTRMMQLDNEYTGQDFTASIKSLNPSILDIGQYLQAVTPNLALGLEAVWQA-VSYCAKYIASAQLVNTSFWRRLTDKVEAGVDLNLKEGVTTVGAKYDFRMS--TFRAQVDSTGKLSCLLEKRV--APPVQLTFAAEMDHFKQAAKIGVAVSIE Caeel GSYEELHRK-ARDVPT-CF--EGAKLMVNKGLFQVSHTLSLYRFGATYVGTNILLGDTDV-NGNTTATGAQATIERKGRLSTLGLTLANIDLVNVGQFLRRLTPRLDVGTEMVYQSVLSYAARYIAAATLVHLTYYHKQNENLAFGVEFECGEAVTTLAYQTELPEEGVTMRASFDTNWTVGGVFEKRLSQQLPFTLALSGTLNHVKAAGKFGIGLIIG Canalb1 GTIENLNKEVARDVLG-QYFFTGLRADLNKAFFQTSHTLSIYAFSALYATDDFLQGNIDN-DLSFSGRMIQLEQDYQANDCSINVKTLNPNFLSVGSILQSLSSKLAVGLETMYSA-VSYVARYIASAQLLIASFWRKVTDKVEAGLETQVIEGQTTIGAKYEYRTA--VFRGQLDSKGKISAFLEKRI--MPTVSILFSGEIDQFKNTSRLGLGLQFE Cangl GTVENLNKEVSRDVLS-QYFFTGLRADLNKAFFQTSHTFSIYAFSALFANDNFMQGNIDN-DFSLSGRMCQLEQDYQASDSSLNFKSLNPSISSVGSLLQSISPQLAVGLEVLYSG-VSYLTRYIFSGQLLVASFWRKVAPNVEAGIETTLIEGSTTIGAKYEYRQS--VYRGSVDSNGKIGCFLERKI--LPTLSVLFCGEIDQFKQESKIGCGLQFE Capow GQYDHINKE-TLEIAT-NYLIDGAKFSVSKGIFNISHTVNLYSFNATYVGPNVLLAEMDH-DGNLNGQGLQLEGDYKGEDFHINTKIFNPDVLNLLNYMQSVTPRLALGTEYRWQSGLAFGARYANQQRLIDFSYFHRVNDKVSAGAELAIMETVFSAGYEYNLRRS--VIRGDVNSRGVVSAVLEQKMGAAL--SFYLTASIDHLKGANKFGIGFVLG Catan2 GKYEELHRK-AQMTTN-HFMFDGCKIDFAKGLFQIHHALHLYSFNTVYATENLLQGMVDT-DGSLNGRMMQAEVDRQGKDYDASIKLVNPWPLDVASYLQSVTQRLALGVEAVIQA-FNVAAKYVATATYLHVSYVHPVSAKVDLASELHVREGKATVAAKYEFRQS--TFRTQIDSNGVVASVLEQRM--GP-MAFTLAGQVDHGKGESKFGFGLALE Cioin GTFEEIHKP-CKDILQ-PF--EGLRFIVNKGLFQAQHTVHLYRFGSTYVGTKVMIGEMSN-EGNLQAQSVQVGGDVVFNDSTLSVVCADPDLLNIVHYLQAITPKLSIGSELLYQAIASIAGRYQAAGTIMHASFYRKANENVQVGVELEAKESVTTFAYQMDLPKMNLLFKGMLTSEWTIGSALEKRL-QPLPITLNLTGTYNIKKDKVAVGIGAVLG CocheC53 GTVENIAREVQRDVLN-NSSFSGLRAELTKAFFQVAHSLSMYSYMVLYGSPRFMQGNIDN-ELAFSGRMVSLENDYTGADFSASLKAVNPSILDMASYLQSVTSRLALGIDAFWTN-VSYAARYMACGQILEASYWRKLTDKVETGINCNLKEGNVTIGAKYDFRQS--SFRAQIDNQGKVACLLEKMI--APPIRVTFSGEIDHKQNAAKLGLAVAIE Coere1 GQFEFLNKE-LKTTLT-NFMFDGGRADLAKLLFQVMHTFQLFEFAGVYADEDMMHGKMDT-EFNFQGRMFQLESEYTGSDYTSNVKAINPSLVDMANYLQSITSKLGIGAELLYQS-ISFAMRYVA--QTLSMSYWRKISEKCEAAAELQAREASCSVGVKYEFAAS--TVRAMADSFGKVSMLLEEKI--APGFSFLISGELDHLKGENKFGVGLNLE Conco1 GQYEHLHRE-VKNVVS-NHLVDGARFDITKGLFQVVHSFSLYNFISLYADENFLQGSVDN-EGSLSARMLQLEGEYVASDCTLNAKVINPGVTDLCSILQSVTPNLALGAEAIFQS-ISYVAKYVLTANFVQASYFHKVNDMAEFGVELQARDAACTLGAKFDFVKS--TFRTQIDTTGRVSAVLEERL--APSLTLTLSGDLDHLKGQSKFGIGLQIN Conpu1 GTAENLQKE-VKSTLT-NFIFDGARADLTKSLFQLTHSFALYNLGAVFANNNLLQGSIDH-DGNVNGRMIQVEQDYQGKDFSLNAKAVNPSPADIGSYFQSLTKNLAVGFETLYQT-TSYLAKYIATAQLLQASYWQKFGEKVEVAADLQCRDAIATVGAKYDLRMA--TFRAQLDSTGKVSALLEQRF--APTFSFLVSGELDHFKNAAKVGVGVMIE Copci GTVEGLQKE-VKSTLS-NFIFDGARADLTKTFFQVTHSFALYNFGAIFATQQFLQGGVDH-EGSVNGRMIQIEQEYQGSDFTLNAKAINPSPADIGSYLQSLTKNLALGVEGLWQA-ASYLLKYIATAQVLQSTYWQKLSDKVEVAADLQVRDAIATLGAKYDLRLA--SFKAQIDSTGKVSALLEQRF--TPTFSFLVAGEIDHFKNAAKVGVGVMIE Croqu1 GTYEQVGRE-VKAVLT-NYIFDGARAELSKALFNVTHSFNLYNFGAMYATNNFAQGSIDN-DATLMGRVTQLEHDRRGQDYALSLKIYNPNPTEIAQYLQSLHPRLSLGLESVWQN-LSYLLKWISTFALMQATYWQKLSERVEAGLELVFRKALTTAGLRYDLRQA--TVRAQLDTTGKVSMLLEHRI--APSFTFSIAGELDHFKSQSKFGVGIQLE CryneH991 GTVENLTRD-VQQVLA-NWMFDGARADVAKVIFQLTHSFSLYNFGVIFANAKFLQGGLDG-SGSLTMRMVQFEHDHIGDHYTFSWKSINPNLLDMASLLHSVSPRLSLGFETVIQA-TSYVAKLTATGHLIQATYYQKLSDKVDVALDFQTREALTTLAAKYDFRMA--TFRGQIDSAGKVGMYLEQRF--TPAFAFLVAGEIDHAKNASKFGVGIMIE Crypa2 GTVENLAKEVQRDVLN-NYMFTGLRADLTKAFFQVSHAFALYTFAALYGTNKFLQGNIDN-DGQLSTRMAQLESEYTGNDFTLNVKALNPSYLEVGQYMQAVTPKLALGLEAMWQA-LAYCGKYVATAQMINTTYWRKLSDKVQAGVDMTLKEGVTTFGAKYDFRMS--TFRAQLDSKGKLSCLLEKRV--AGPVMMTVGADVDHATQTAKLGLGISIE Debha1 GTIENLNKEVSRDVLT-QYFFTGLRADLNKAFFQTSHTLSIYAFSALYAAEDFVQGNIDN-DLSFSGRMCQLEQDYQASDFSINLKTLNPSFLNVGSLLQSLTSKFAVGLEAMYSA-VSYVARYIASAQLLIASFWRRVTDKVEAGLETQIVEGQTTMGAKYEYRQS--VFRGQVDSTGKVGVFMEKRV--LPTVSILFSGEIDHSKNASKLGLGLQFE Dekbr2 GTMENLNKEVEKDVLT-QYEFSGLRADLSKTFFQVSHSFSTYAFAGMFASDDFIQGTIDN-ELSLTGRMCQIEQDYQANDFSLNFKTLNPDF-SVGSILQSITPKFALGMETAYSG-ISLVGRYIASAQLLTAAFWRKVSDHVEAGIETTLLDADTTIGAKYEFRQS--IYRGQLTSNGVASFMLEHRI--LPTLGLTFTASIDQLKNTSKMGSGLQIE Dicdi GKAED---M-ISEVVN-DDIYEGAKVDVTFKIFETSHQLNVYSNQNVYSKDSLLYGKIDS-ERRLFGRAGELEFKLPFMNFCLKADTEN-----GFSFLTSISKKLAIGYE------NSYLFNHSLVVGNSSYVYRQK---NLHIGTDLVMFMSEYSFGVRYAFQQS--LVKFRADSHGSIFGSYDQMI--NSFTKLNLSGSLNYFAQDYKFGLGLTFQ Dmel GTVEELHKK-CKDIAI-TF--EGAKIMLNKGLFQVSHTINMYRFGATYVGTKVLLGDIDP-AGNLNANASQLTTDYRGSDYTLSLTVANPSIFTVGQYLQSVTPALALGSELAYQAIMSVVGRYVWSGTLLHVCYYQKASDQLQIGAEVETQESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRL-APLPFTLALSGRMNHVKNNFRLGCGLMIG Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba GSFDTLGRE-VREVAS-SFFFDGFKVEIAKGMLQVMHRLRLYSLGSMLVPNEFLMGDFDTGSKAFNGRAHSLEADYMGKDSSGAVRVYQPNPLDVYNYLQKVTPSLALGMEGTAMS-MTLVARHVGIATLSQFSYFQQVTPLVQAGSELELKAAVCTFGIRVNLQAN--TIRAQLDTAGRLGVHFEERV-IPNVFNIHLAGQLDYVKNTSQFGFGLSLG Fomme1 GNVENLQKE-VKATLT-NYIFDGARADLTKALFQVTHSFSLYNFGAIFANSKFMQGGVDH-EGAVNGRMLQAEHDFTGQDYSLNLKALNPSPIDIGSYLQSVTKNLALGSEVLVQT-PSFLAKYIASAQVLQTSYWQKLNEKVEAAADLQIREAVATLGAKYDLRMS--TFRAQLDSTGKVSAMLEQRF--APTFAFMVAGEIDHFKNNAKIGVGVMIE Fusgr1 GTIESLAKEVQRDVLN-NYMFTGIRADLTKIFFQVSHQFAMYTFAAMYGTGKFCQGNLDN-EGSLSGRMAQFEHEYTGNDFSASLKMLNPSYLEIGSYLQSVTSKLALGLETLWQA-VSYAARYIATAQLLNTSYWRRLSDKVQAGVDLSLKEGVTTIGAKYDFRMS--TFRAQVDSKGKLSCALEKRV--APPVMMTFAADIDHFTHQAKIGLGVSIE Galma1 GSVENLQKE-VKATLS-NYIFDGARADLTKSLFQVTHSFALYNFGAVFANQKFLQGSVDH-EGSISARMIQLEHDYHGQDFSANLKAVNPSPINIASYLQSVSKNLAFGVEGLYQA-LSYLAKLIATAQILQATYWQRLSEKVEVAADLQVRDAIATLGAKYDFRAA--TFRAQVDSTGKVSALLEQRF--VPAFAFLVSGEIDHFKNSAKVGVGVMIE Ganpr1 GIYENLHGE-VRNVPS-VMMFDGAKFEIGSVMFQVSHQLRWYTFNSIFANERLLRGQIDS-DGVLQAIMLNLEHDYVGSDFAASLKLINPNPIDVLQYLQSVSKNLALGGEYVLQV-FTIVAKYTWTTTFMHTSYHHKLNQRLELAAELQAREGIATIGFKAETMFA--QIKGSIDTQGKVQAVLEERL--APQLAFTITGEMDYTKPQGRIGVGFQLE Gloin1 GTFEGLHKE-VKATLT-NHLFDGGRADLTKVLLQVTHSFSMYNFGAAFIGINFLHGTIDT-EGNLTARMLQLEQDYQGTDYSINCKTINPSPVEILSYFQSVTQKIALGVENVYQT-RSLVAKYIATLQWLQASYYQKISEKVDFGTELQIREAVCTVGGKFDFRAA--TFRGQIDTTGRISSVIEQKI--APGFSFIITGDIEHMKSTARFGVGIQLE Hisca1 GTVENVAREVQKDVLT-NFMFTGLRADLTKVFFRVSHAFTMYTFSSMFGSPKLLQGNLGN-DGALAAVLIQIDNDYTGSDFSASLKAFNPSYLEVGSYLQSVTPNLALGLEAIWQA-VSYCAKYIASAQLISASYWKKLSEKVETGVDMTLKEGTATVGAKYEFRAS--TFRAQVDSSGKLSCLLEKRV--AMPISLTFAGEIDQVKQQAKLGLAVSFE Klula1 GTVENLNKEVSRDVLT-QYFFTGLRADLNKTFFQTSHTFSMYAFSALFANDNFMQGNVDN-QMSLSGRMCQLEQDYQASDFSLNFKTLNPSAASVGSILQSITPQLAIGLEAIYSA-VSYMTRFIFSGQLAVASFWRKVSPNMEAGLETSLIEGATTLGCKYEYRQS--VFRGSIDSNGKVGCFLERKI--LPTLSVLFCGEIDHFKNESKLGAGLQFE Lacbi2 GTVENLQKE-AKATLS-NFIFDGARADLTKSLFQVTHAFALYNFGAIFANQRFLQGGVDH-EGNVNARMIQLEHDYQGQDFSLNAKAINPWPADMGSYLQSLTKNLALGVETLYQS-TSYLAKYIATAQMMQATYWHKLSEKVEVAADLQVRDAIATLGAKYDLRLA--TFRAQLDSTGKVSALLEQRF--TPNFAFLVSGEIDHFKNAAKVGVGVMIE Lenti61 GTSENLTKE-AKNTLN-NYLFDGARAELSKGLFSVTHSFNLYSFGAMFANENFMHGSIDH-EGSLSARVLQVEHDYSGTDYTLNAKAINPSPADMGSYLQSITKNVALGIEGILQA-AAYLAKYIATAQLLQATYWQKLSDKVDVAADLQVRDALATLAARYELHTA--SFRAQLDSTGKVAAFLEQKF--APTFSFVVSGEIDHLKNAAKVGVGVMIE Malgl1 GTVEKMQNE-VKMVTT-NFQFEGARADLTKALFQVTHAFTLYNFGAVYGDENFYQAGLDD-AGNVTMRFVQLEHDFQGSDYSINFKALNPSPTNVGNYLQTLTPRFALGAEAVYQS-IGYMAKWIATAQWGQLTYWHQLSEQVDVASDLQMRDAQASLSARYSFRMS--SLRAQIDSLGKLTSVYEARI--SPAFAFTFSGELDHLSGGAKVGLGVSIE Mellp23 GTYEQVGRE-LKGVLT-NYIFDGARAELSKALFNVTHSFSLYNFGAMYATNKFAQGSLDN-DATLMGRVTQLEHDRRGQDYSLSFKIYNPNPIDITQYLQSLHSRLSFGIESVWQS-LSYLLKWISTLNLLQATYWQKLSDKVEAGLDLVCRKALTTFGVRYDLRQA--TIRSQIDSHGKVSMLLEQRI--APTFTFSIAGELDHFKSQSKFGIGIQLE Mnele GSFEELPRK-TKEVAK---PFEGCKFTWNKMIFQATHTINMYKFGTTYVGSKILISEYGG--GMVQFQMYQADVGYKGENFSAQITGVNASIINVGHYLQRISKNLSLGGELMFQAMITYGGMYVKTGEQTHLCYYNKGNDQVECGVEFEYGESVTTFGYSIDLPKGLSKFRGSVDSDWSVTGVLEKRF-EAFPFCFSLSGLLNHKKNQAKFGIGFTIG Monbr GSYDLLHNE-YRGLAA-NFAFEGARFSFSKPVMQLQHQVHLYHFTPTYVGTLIVMADLDH-KGSLTAQGVQVETDYDGADFHVGLKAVNVDPLNVFNYLQKITQRLALGGECMWQAIPSFGGRYTTSVTMLEASYQHDYSDTIALGTNFELASCTANVGFQSRFSSA--MVRGQVSTAGVITSVYEKTL--APGVNFTVSAILDHLKGDSAFGLGLTIG Morel2 GTFEGVNRE-VKHTLT-NHVFDGARCDITKVLFQVTHSFAMYNFGTAFIGQQFLSGNLDT-DGNVQARMLQIEQDYNGKDFNLNLKGVNPSPTEITSYLQSITPNLALGAEAVHQT-YSYVAKYIATATYLQASYYLRYSEKVDFGTEIQLRDAVATVGGKFEFRRS--TFRGQVDTTGKVAAVLEEKI--VPGFSFLISGEMDHGKGQSRFGVGMMWE Mucci2 ---------------------------------------------------------MDN-DTNLNGVMLQVEQEVNGSDYSMTFKTMNPNPLEMASYLQSVSQRLVVGSEIVLQA-MSLVGKYIATAQFIQASYYQRINEKVDFGVELNLREAVATVGGKFDFRQA--TFRGQIDTTGRVSAVLEEKM--APGFSFLISGDLDHMKGQSKFGVGIMLS Mydma GVFEDLHKK-CKELPG-NF--DGFRLMVNKGLFQVSHTLNLYHFGATYVGGSVILGDIDN-SGSLSAQMVQADVDYRGDDFTTTCTLGNIDILNVAHYLQRVTDNIDIGTELLYHAILSLAGRYVAAAQIWHASYYRKGNDNVQVGVDYEYQDSNVSLGYQIDIPKANVTFRGMVDTNWAVGGLFEKKL-YPLPFSFILSGKLDHLKNQSRFGFGLQIG Neucr2 GTIETIAREVQRDTLT-NYMFSGLRADVTKAFFQVSHQFAMYAFAALYGTNQFAQGNLDN-EGALSTRMAQFEHEHLGDDFSASLKAINPSFLDVGDYLQAVTPRLGLGLQAVWQA-ISYFARYVASAQLLNTSFWKKLTDRVQAGVDMTLKEGITTFGAKYDFRMS--TFRAQIDSKGKLSCLLEKRL-GAAPVTLTFAADVDHVTQQAKLGMSVSIE Orpsp11 GSFESLHRE-AKSVASPQYLFEGAKIELQSNLFQVTHLMSFYIFGAVYAGAKLLQGQIDT-DGSLFARVINLEHDHVGKDYAINLKLFNPNIVDIASFLKSINKNLTVGAEYLLQN-ISFVARYVLTTTYFNASYYYKLNHRLEMATELQAKEALCTAGFKLDTHYA--TIRGIVDSKGKIGTVLEERL--APGFAFT--------------------- Pench1 GTVDNLAREVQKDVLT-NFMFSGLRADLTKVFFRVSHAFSMYAFSAMYGSPRFMQGNYGS-DGALAAVLVQIDNDYTGRDFSASLKAFNPSCLEVGSYLQSITPSLALGFEAIWQA-LSYSAKYIGTAQLFNATYWRKLSERVEAGIDMNLRDGTTAIGAKYDFRAS--SFRAQVDSTGKVSCLLEKRI--AMPISLSFAGEIDQSKQTAKLGLAVSLE Phybl2 GSFERLHRE-VKDTTT-NYLFDGAQANIVKELFHVQHQFSLYNFMSGYMTERMVQGTMDN-DTNLNAVMLQVENDYTGSDFSLNLKAMNPNPMEMASYLQSVTSNLAVGSEVVLQA-MSLVAKYIATAQLIQASYYQRINEKVDFGVELNMREAVATVGGKFDFRQA--TFRGQIDTTGRVSAVLEEKM--APGFSFLVSGDLDHMKGQSKFGVGIMLS Picst3 GTIENLNKEVTRDVLN-QYFFTGLRADLNKAFFQTSHTLSIYAFSALFATDDFVQGNIDN-EMSFSGRMIQLEQDYQANDFSINLKTLNPSLLYVGSLLQSLTSKFAVGLEAMYSA-VSYVARYIASAQVFIASFWRKVSDKVEAGIESQIFEGQTTIGAKYEYRSA--VFRGQLDSNGKVSAFLEKRV--LPTVSLLFSGEIDHSKQLSQLGLGLQFE Plicr1 GSVESLQKE-VKMTLT-NYIFDGGRADLTKSMFQVTHAFALYNFGAVFANQNFLQGGVDH-EGNVNARMIQLEHDYQGRDFSLNAKAINPSPTDVGSYFQSLTKNIALGAESMLQA-TSWLGKYIATAQIVQATYWQKLSQKLEVAGDIQIRDAVATLGAKYDLHAA--TFRAQVDSVGKVSALLEQRF--APTFAFLVSGEIDHFKNAAKFGVGVMIE Polpo GKFEDINRI-ASEVSP-QDAFDGFKCEVSGMSFQFSHAFHMYALTTVFSDETTAIGKVDS-DGKVFGRGGEIEHKHPTQNIVVKYDANN-----AAGYIRSITKRWAGGLEI---P-AQRLFMYVFTANNMTYSFKKA---NAELATELQMLASKLSVGLRYGFTQQ--VFKIRADTEGTVVGMYEEKL--TPSFRISFCSTLNYFTNDFKFGIGLSIS Pucgr2 GTYEQVGRE-AKGVLT-NYIFDGARAELAKALFNVTHSFNMYSFGGMYATNNFAQGTIDS-DATLMGRVTQVEHERHGQDYALSMKAYNPNISNITQYLQSLHPRFSLGIESVWQS-MSYLMKWISTLTLLQASYWQKLSDQVEAAVDLHFRKAVSTVGLKYDFRQA--TVRAQADSTGKVSMLLEQRI--APMFTFSVAGELDHAKSQSKFGVGIQLE Punst1 GTAENLQKE-VKNTLT-NFFFDGARADLTKSLFQCTHSFAMYNFGTVFASNDFLQGGVDN-EGNVNARMLQLEQDYQGKDFSANVKALNPSPADVGNYLQSVSKNIAVGFESVLQT-TSYLGKYIATAQVIQATYWQKLSEKLDVAADLQVRDAVATLGAKWDLRAS--TFRAQLDSTGKVSALLEQRF--SPALAILFAGEIDHFKNASKFGVGVMVE Rhior3 ---------------------------------------------------------MDN-DTNLNGVMVQLEQEVNGSDYSLNFKTMNANPLEMASYLQSVTQKLVVGSEIVLQA-MSLVGKYIATVQFIQTSYYQRINEKVDFGVELNLREAVATVGGKFDFRQA--TFRGQIDTTGRVSAVLEEKM--APGFSFLISGDLDHMKGQSKFGIGIMLS Rhoto1 GKHEDLGRE-VKLTLT-NYTFDGARADLAKTLFQVTHSFVAYNFGAVYATPKFMQGMVDN-EGSVTGRMFSLEHDRVGKDYTLSVKAYNPSPADIAAYLQSITPHFAVGVETLYQS-LGYMAKWIATAQVWQATYWKKLADRVDAGVDLVCRKAVATAGVKYDFRTA--TFRGQVDSTGKVSALLEQRL--SPAFALSLAGEMDHVKQTSKWGFGASIE Rozal11 NAFEDFNKE-SRLMPA-LMLFDGAKADMALGLFHVVHSFQLYTFSAMNGNEKLLQANMSA-SGMLMARRIQAEADYCGSDYLVSFKTFDPNILRVANYVQSITKKLSAGVEFVYQS-ISYALRYVGSAVLLNLSYHQRISDRVEIGTDFNFKESHTTIGGKVDFKLS--SLRAQIDTRGKLATFFEHRL--GPGVSVLFSGEIDHLRTTGKFGIGIQVE Sacce1 GTVENLNKEVSRDVLS-QYFFTGLRADLNKAFFQTSHTFSIYAFSALFANDNFAQGNIDN-DLSVSGRMCQLEQDYQASDFSVNVKTLNPSFSEVASFLQSVTPQLALGLETLYSG-VSYLTRYIFSGQLLIASLWRKVAQNVEAGIETTLVEGSTTIGAKYEYRQS--VYRGTLDSNGKVACFLERKV--LPTLSVLFCGEIDHFKNDTKIGCGLQFE Salro GSFDSLHNE-IRGVPA-FMVFQGARFAFQKPVLALTHSIILYKLQPTYIGTMICIGEVDH-AGRLMANGTALETEFAGSDFSAGLKMLNVNPAKILNYLQRVTSRFSLGAELQYQSGLNFGGKYLLAVTAMQASYVHQIAKNTTAGCELEMRQVQASVGVQYSFKNS--TFRGQITSGGVVMGYFEKQL--VPAFTFIVSAILDHVKSETVFGLGLQIG Schco3 GTTENLQKE-VRATLT-NLMFDGGRADLSKTLFQVTHSFSLYNFASVYATDSFLQGSIDH-DGNVNMRMV-LEHDYHGRDFTINLKAMDPWPADTGSYLQSFTKNIAVGFESLWQM-TSYLLKWISTAQVLQATYWQKLSEKVDVAADLQVRDAVATLACKYELRLA--AFRAQLDSTGKVSAFLEQRF--SPAFSFLVAGEIDHFKNAAKFGVGVMIE Schpo1 GTCENLSKEVSKDILS-NYAFTGVRADVTKGFFTVSHAFALYSFSTMFGGEPFLRGSVDN-DGAVQAMMCQIEHDHKGKDFSFSFKAMNPWYEEIISLLQSVTPKLSLGVEALWQATLSYMTRYIATAHLVTATFWRKLSPKVEAGVECQLPEGLTSVGVKYEFAQS--IYRGQVDSKGRVGVYLERRL--APAITLAFSSELDHPNRNAKVGLGLSLE Sorma GTIETVAREVQRDTLT-NYMFSGLRADVTKAFFQVSHQFAMYAFAALYGTNQFAQGNLDN-EGALSTRMAQFEHEHLGDDFTASLKAINPSFLDVGDYLQSVTPRLGLGLQAVWQA-ISYFARYVASAQLLNTSFWKKLTDRVQAGVDMTLKEGITTFGAKYDFRMS--TFRAQIDSTGKLSCLLEKRL-GAAPVTLTFAADVDHVTQQAKLGMSVSIE Sphar GPFEILHQE-VKGIAQ-NYLIDGAKVSVSKPIFQVSHSLNMYHFGVNYFGTPVLIGDIDG-QGNLMAQMTSLELEYRGNDFSAAVKAINPDVVSIANYWQSVTQRIAVGAEALYQGGMSLGIRWTSCVSLFAVSYGHRVSDKVTLGVELEGKDSVVNVGYEYNLRQS--AVRGQIDSHGVVSGVLENKLAPAL--SFLLTGQLDHASGKSMFGLGFVLG Spipu1 GSWEGLHRE-AKMVPT-NFLIEGAKFDLTSVLFQVMHSFSWYHFGTVYAKDKMLHGQVDD-QGGLQARMVQLEHDHVGSDYSFNVKAVNPNPVDQLAYLQSVTQSVALGTEFVYNS-LSYALRYVFTATFLHSTYWRRLNQRLEVCAEVQLREGIASVGFKLDTINA--SIRGMVDTMGRLSAVLEERI--VGGLAFHLSGEIDYAKGGGRVGIGFTLE Sporo1 GKFEDLGRE-VKLTLS-NYTFDGARADLSKTLFQVTHSFALYNFGAVYATSKFLQGMVDN-EGSITGRMLSVEHDRVGKDYTLSFKSYNPSPVDIAAYLQSLTPHFAVGVETLYQS-VGYMAKYIATGQIWQATYWKKLAERVDAGVDLMVRKAVATAGVKYDFRMA--TFRGQVDSTGKVAALLEQRF--SPAFAFLVAGEIDQVKNTSKFGVGIQVD Stehi1 GSVENLQKE-VKNTLT-NFFFDGARADLTKGLFQVTHSFSLYNFGAIFANANLLTGHVDH-EGAVNARMIQLEQDYGGQDFNMNVKAINPSPLDVGSYLQSISKNLALGFETIYQT-TQYVAKLIATATVMLATYWHKLSEKVDAAAELQVRDAIATLGAKYDLRMS--TFRAQVDSTGKVSALLEQRF--APTFTFTVAGEIDHFKNAAKVGVGVSIE Tapde11 GTVEHISREVQMDVLS-RQMFTGIKADITKVGFHMTHSFASYSLAAAFATNRFMNGNVDN-DGSVSGRMLQLEHDWKGNDFSINLKTVNPSFLDIAHYLQSVTPTLALGLEAIWQTTLSYVARYIASAQLLGACFWKKLSAKVEAGVECQLTEGTTTIAAKYDYLHS--TLRGQLDTKGKLQCLFEKRL--SGAVSLTFAATLDHFKNNATVGLGVNLE Thetr GGFEEYSRE-AMRIPM-AELFDGARLELKKPIFVTSHTVVMYMFGASYVSQDALISKMDT-MGILRAHVLNIDLDHKGDDYAAQFKLVNDQAL-FFNYMQKVTPELAFGAQLDYYSIISIAARYVATAKALTVNYMHKVNDSFSMATQLDFRDSSFKVGYEYLLQSG--KFRGQVDSAGKIGMCVQESL--IFGIMLQLCGIVDHKKQVFKFGIGLTIG Treme1 GTAENLTKE-VQQVLA-NWFFDGARADISKVVFQLTHTFSLYNFGAIFANANFLHGSVDG-QGQVTARMVQIEHDHLAPHYTFSLKSMNPGLLDFVSLLHSIGPRLSLGFETIIQS-TSYLAKLIATAQLVQATYYQKMSDKVDVALDLQTRGATATLGAKYDFRPA--TFRAQVDSNMKVGMLLEQRF--TPAFAFLVGGEIDHARNTSRFGVGIQIE Trire2 GTIENLSKEVQRDVLN-NYMFTGIRADLTKIFFQVSHQFAMYTFAAMYGTGKFCQGNVDN-EGSLSGRMAQFEHEYTGDDFSASLKMLNPSFLEIGSYLQSITPKLALGLETLWQA-VSYCARYVATAQLVNASYWRKLSDKVQAGVDLSLKEGVTTIGAKYDFRMS--TFRAQVDSKGKLSCLLEKRV--APPVMMTFAADIDHFTQQAKLGLGVSIE Umbra1 GKFERLHFE-TKDTLT-NYIFDGAQANIIKELFHVQHQFSLYNFMAGYTTERMMQGTMDN-DTNMNGTMIQLEQDYIGTDFSANVKAMNPSPLEMASYLQSLTSNFAVGSEFVLQM-MSLVGKYVATAQFVQATYYQRINEKVDFGVELNLREAVATVGGKFDFRQA--TFRGQIDTTGRTSAVLEEKM--APGFSFLVSGDLDHMKGQSKFGVGIMLS Ustma22 GTVEHLQRE-VKGVTT-NFMFDGARADLTKAIFQVTHAFSMYNFGAVYGDNKFFQAGLDD-GLNVTMRFVQIEHDYQGTDHSANFKALNPSPTDIVNYLQSLTRNFAFGVETVYQS-TGYIAKLIATAQVAQCTYYHKLSEQVDVAADLQMREAAATLGARYNFRMA--TLRAQIDSAGKLSSVYETRL--SPAFGLTFAGEIDHLQGAAKFGFGVSIE Walse1 GTAEAMGRE-AKTTLS-NFIFDGARADLTKGIFQVTHSFSLYSFGAVYADAKFLQGAVDH-TGTLTGRMIQLEHDYQGLDYSINGKAMNPSLVDIGSYLQSITPNIALGLETLVQL-TSYLVRLLATAQILEATYHHKLSDKVDAAATLQVKEASASLGAKYDFRMA--SFRGQLDSTGKVSALLEQRF--TPAFAFLVAGEIDHLKNASKFGVGIMLE Zygro1 GSVENLNREVSRDVLT-QYFFTGLRADLNKAFFQTSHTFSIYALSALFANDNFIQGNVDN-DLSLSGRMCQLEQDYQGSDFSLNFKTLNPSLSSVGSLLQSVTPNLSLGLEVLYSG-VSYLTRFVFSGQMLIASFWRKVTPSVEAGIETTLIEGSTTLGAKYEYRTS--VYRGSVDGNGRVACFLEKKI--LPTLSVLFCGEIDHFKSESKLGCGLQFE [Cluster1768.fasta_al_trimmed; alignment length = 196] Allma1 MPKSKRQRTVHLTRTKGG-RPAKDKLITAIRDAAESFKYIHVLAVENMRNVALKDVRSEWA-NS-RFFFGKTKVMALALGTDAAAEVLPDVHVLANK-LGQVGLLFTSEEVVEFFKSYDFARAGNIARETVTVPEGFPHNMEPQLR-KLGMPTILKKGIVSLYTICTKGKALTSEQAQLLKLFQADFRMH-LLAYY Ashgo11 MPRSKRSKLVTLAQTKKG-RENKERIFDEVRQALDTYRYVWVLRLEDVRTPVLQEIRSAW-AGS-KLIMGRRKVLEKALGGTRETEYKENVSGLVKQ-CGMCGLLFTDETVTAYFREYDYSRAKSRAPLRVEIPAGMVHSLEPTLRNKFKMPTRIQNGKITLYLVCEAGETLDVRQALILKQFAAEFRVK-LAAYY Aspfu1 MPRSKRARIVHESKVKKSHKEQTRRLYANIRECVEKYDHLFVFSVDNMRNTYLKDVRTEF-ADS-RLFFGKTKVMAVALGHNPENEAAPNLHKLSPY-LGAVGLLFTSESVLSYFDAFDFARAGTVSTRSFSIPNGVSHTIEPELR-KLGVPTRLVKGKVMLYPVCKEGEVLDSRQTTLLKMFTAEFKVD-LKAQW Aurde31 MPRSKKAKVVSLTKVRKT-RENKANHITILQECADKWKYCYVFQVANMRNTYLKDIRVRW-KDTGRMFFGRNTVVVKALGATEAEEHKPGLSKLNKH-LGTVGVFFTDAETEAWFAHYDYARAGNRATRAVELPAGFQHTMEPQLR-RLGLATRLERGVPTLHVVCKQGDVLTAEQAQILKLILATFRVR-LLCRW Batde5 MPKSKRSKIYNLTKAKKG-KPAKENLFNEIRESVDKYAYIYVFEVMNMRNVYLKEVRNDW-SGS-RIFLGRNRVMAKALGTTEESEYKLNLRELSLK-LGDVGLLFTNEEVKKYFEGKDYARSGTIAESEIIIPQGFPNNMEPHLR-SLGMPTMLVNGVIQLYTICKKGATLTPEQAHLLKHFLAEFHII-PKYYY Botbo1 MPRSKRSKVVSLTKTKKG-REHKAEMITQIQANADKWQHVWVFSVGNMRNSALKDVRERW-KGTGRMFFGRTAVMAKALGTTDAEEYKPGIHKLAQR-IGPVGIFFTDQEVIDWFASYDFARSGNVARKEVVLPAGFPSSMDPQLR-KLGLTTKLVRGVPSLHIICKKGDKLTSEQAQLLKLIMATFKIR-LIGRW Botci1 MPKSKRARVVHLTKVKKG-KELSLKLFANVRESLDSYQHCFVFSVDNMRNTYLKDVRNEL-SDC-RLFFGKTKVMAKALGSDPSSEYQPNTSLLSPH-LGNVGLLFTNSSIITFFQDLDFARAGTEASRNFTIPAGMAHSLEPELR-RLNVPTTLTKGKITLYCVCNEGDVLDSRQTRLLKLFTADFSVQ-LLAYW Caeel MARSRRDKNVSLTKVKKT-KDTKNNLVNEVRASVDQYKNLFIFTIANMRSTRFIAIRQKYKENS-RFFFGKNNVISIALGKQKSDEYANQLHKASAI-LGQCGLMFTNKEVEAEFSEADYARVGDVATETVVLPEGFAFSMEPQLR-KLGLPTKLDKGVITLFEVCKEGEPLTVEQAKILKHFMSQFRLI-FKAHW Canalb1 MPRSKRSKLVTLAQTKKG-KENKTRLFDEVRSALDTFKYIWVLQFDDIRTPVLQDVRNDW-VGS-KLILGKRKVLQKALGETIEEEYKDNLHQLSKL-CGLPGLLFTDETVEAYFKAYDYSRAKSRAPIDFTIPAGMSHSLEETLRNKLKVPTKIKAGKIILYVVCNKGDVLDTRQALLLKQFASEFKIP-ILGYY Cangl MPRSKRSKLVTLAQTKKG-RENKERIFDEVREALDTYKYVFVLQLDDVRTPVLQEIREAW-VGS-KLLMGKRKVLEKALGTTREQEYKENLSKLTKY-CGVIGLLFTNDTVKEYFEAYDYSRPNSRAPITFEVPEGMAHSLEPTLRNKYEMPTKIKAGKITLYLVCKEGQKLDVRQALILKQFLAQFKVI-ISAYY Capow MPKSKRVKKVALTRTKHG-MESKDALVNEIRSCIQKYSSVYVFAVRNMRNIKLKDVRSEW-KHS-RFFFGKNRVMALALGNSEENEQETNLREVSNM-LGQTGLLFTSEEVIAWFENHEFARSGFVSSETVKIPAGFSHTMHNDLL-RLGLPIVLNKGIITLHTVCSKGDTLTPEQARILKLILADFHIK-LKAAW Catan2 MPKSKRQRVVHLTQTKVG-RPAKSALVDKVRAACDAYSSIYVFSVTNMRNSSLKTLRDEFADDS-RFLMGKVKVLAKALGEDAAEEYLDSLHLLTQR-VGQVGLLFTNKAMVEHFKKYDYARAGNVATETI-----FPHNMEPQLR-KLGLPTKLDKGVVTLYTVCEQGKVLNADQAQLLKLFQAHFRLF-FLAYY Cioin -----------------------------------------------MRNSKLKEVRNAW-KHS-RFFFGKNKVMALAFGRSPETEIMNGLYKFSTK-LNEVGVLFTSEDVVDWFDKYDYARTGNIATSTVELDEGFSHAIEPHLR-KLGLPVALKKGVVTMHTVCKENEKLTAEQAKVLKLLMSQFSIH-LQCMW CocheC53 MPKSKRAKVVHLTKTKKG-KELSLKLFANVQEAADNFEHIFVFAVENMRNSYLKEVRAEF-ADS-RFFFGKTKVMAKALGQTPAEEHLTNLSQLTEH-LGNVGLLFTNSEIIEYFANYDFARAGVVATQTFTVPAGLPHSMETTIR-KWGMPTRLDKGKIILYTIAEEGKPMNSHQTALLKLFMADFKID-LKAYY Coere1 MPKAKRVKVVELTKTSKK-KDGRKQIMASVNDAVAEYDYVWVFSVENMRNQYLKKVRKSM-DTS-RFFFGSNKVMARALGNTPEEELKDNLHKISES-LGDVGLVFTNEEAKKAFDSFDYARAGNVAAYQVVIPAGFPNNMEPQLR-ELGMPTRLKQGKITIYVICNKGDKLTPQQANLLKHFMAIFKVQ-LVAYW Conco1 MPKSKRQKLVSLTKTPKN-RDDKERLIEEIQKFVETHQHIFIFSLLNSRSSYMKDVKTEW-KSS-RFFFGKNKVMAKALGTTPEEEVRPNLSKLANL-LGEVGLLFTNSTVQEYFQNFDYARSGVEARELIVIPAGFPHNMEPQLR-SLGMPTFLDKGVVTIYTVCKPGDVLTPNQAQLLKLFTAEFQVK-LTHHF Conpu1 MPRSKRAKIVSLTKVKKT-REDKSTLIEEVQQNIEKWKYCWLFEVGAMRNAYLKTVRKLW-KDSARIFFGRGAVMAKALGTTVEEEHRPGLHKLAKQ-IGQVGLLFTDSEVTEWFDDFDFARAGNLATRTVTLPAGFPHNEEPQLR-KLGLGTVMKRGVPTLHRVCAEGKPLTAEQAQLLKLIMVEFRVV-MRARW Copci -------------------------MMNELQVNAEKWRYCWLFEVGSMRNAHLKTVRNLW-KDSARIFFGRGAVMAKALGTTPEEEHKEGIHKLAKQ-IGQVGLLFTDQEVIEWFADFDFARAGNIASRTVILPAGFPHNEDPQLR-KLGLTTIMDRGVPTLHKICTQGKPLTAEQTQLLKLIMVHFRVG-LLARW Croqu1 MPRSKRATVVHLTKTKKT-KEAKSKLMDDVKAAAEEFQYAWLFTMDHMRTTYLQEIRAAW-KPA-KIFLGRNAVMRLGLGSTPENEHMPGIGVLGKL-LGDTGLLFTDKVVMEWFADFDYARKGNVATETVELPAGAPGSLDSHLR-SLGLPTSLQRGVPTLYTVCSLGETLNTQQAGLLKTLMAQFRVV-LRHVW CryneH991 MPKSKRSRLTTLSKTRST-KASKQALVNEIRENVDKYDYCWMFSVGDMRNDGLKEVRAQW-RGTGRFFFGKGKVMAKALGDTPETEYQDGLSQIAKR-LGQIGLFFTSDETVEWFDSWEYARMGAKSTMDITLPAGFPHSMEPQLR-ALGLTTSLVRGIPSLHVLCVKGEKLTSEKCRILKLLMADFRIH-LGSRW Crypa2 MPKSKRAKTYHLTQVKKT-REQKEQLFQNIRATVPDYKHCFVLGFDNMRNNHLKDVRREM-VDS-RIFFGKTKLMSRALGTDPSTAVAENIHRLSRH-IGSVALLFTNEEVAAYFASFDFARAGAVATRDFVIPPGLGHTIEPELR-RLGVPTRMVRGKVVLYTVCKEGQTLDSRQTRLLKLFLSEFRVR-VLAYW Debha1 MPRSKRSKLVTLAQTKKG-KENKTRIFDEVRSALDEFRFVWILQLDDVRTPVLQDIRTDW-AGS-KLILGKRRVLEKALGDTPEEEYKDNLHKLSKL-CGVSGLLFTNDTVQAYFTAYDYSRAKSKAPIDFTIPEGMSHSLEETLRNKLKVPTKIKAGKIILYVVCTEGETLDVRKALLLKQFASEFKVN-TIAYF Dekbr2 MPRSKRSKLVTLARTKKG-RANKVRIFDDVRKALDTHRYVWALDLEGLRTPDMQDLRRDW-TGS-KLILGKKKVLRKALGETPEEEYKDNLNELTDYDSGFVGYLFTDETVEAYFRAYGFSRAKSKSPITFVVPEGMQHTMEPMLRNKFEMPTKIVKGKITLYPVVKEGEVLSVKQALILKTFAAEFRVK-MLAYH Dicdi MVKSKRNVVVNMTKVKNP-GEKKKKLVSTIKDIVDQYKFIYLFTFENMRNNKLKSVRTEW-STS-KFLFGKNKVLSVGLGKSEEDELKPNLHKLTEH-LGECGLFFTNDKVFEYFTNYDFPRSGFVSEETITIKEGMTHSMETYLR-GLGLPTTLKNGVIFVYTLCEAGVAVTPEQSQLLKLFISEFKFH-IKGFW Dmel MPRSKRDKKVSLTKTRKG-LAWKQRIVDDIRFCVGKYPNIFVFQVQNMRNSLLKDLRQELKKNS-RFIFGKNRVMQIGLGRTKSEEVEPELHKLSKR-LGQVGLLFTDEEVLEWAENYEYARSGFVATETVTLPAGFAHSMEPHLR-SLGLPTKLEKGIVTLYTVCEEGKVLTPEQARILKLVMAKFRLT-MKCSW Enthi MSREQQGRRVA----K---KEIKNRLITNIQEAAQKYSTVFIFYTPVLRSKFMNIIRKDW-RDS-IFFFGSNKVMQVALGRTEQDEIKPGYHFIAER-LGTCGLCFTNEEILAYFKTQDFARSGSVATMDFVVPEGFEGSLELHLR-KNLLPVELKDGILSCYVVCKKGQKLTPQAARLLEYFMAVFEIR-VLSIV Falba MARSRRAKLVSLTNTKRG-REQKENLITEIQEAIERFNNIYLFSVEHMRNTFLKDIRADL-PDS-RFFFGKNRVMSKAFGVALSDEPHPGLAEIGRR-LGNVGLLLTNDEIVDYFATFDYARAGAIASETIELSAGVAHPMEPTLR-QLGMPTSLVQGVVTLFTICTKGQAITSEQSHLLKLLLSEFRVT-LLVHW Fomme1 MPKSKRAKVVSLTKVKKT-KEQKASLINEIQENADKWRYCWLFEVGTMRNTHLKTVRSLW-KDSARIFFGRCAVVAKALGSTPEEEYKPGLYNIAKQ-LGQVGILFTDEEVTEWFDDFDFARSGNIASQDVILPEGFPHNEEPQLR-KLGLHTSMVRGVPTLHRVCTKGKELTAEQAQLLKLIMVVFRVH-LRARW Fusgr1 MPKSRRAKVVHLTQVKKT-RENKDKLFQNIRDTVPEYQNCFVFSVDNMRNNHLKDVRREL-SDC-RVFFGKTKLMAKALGQTPEEAIAPGIEHLSKY-FGTVGLILTNEEILTYFENLDFARAGAVATRDFSIPTGLAHTIEPELR-RLGVPTRMVKGRVVLYTVCKEGDVLDSRQTRLLKLFMSEFKVK-VLAYW Galma1 MPKSKRSKLVSLTKVKKT-KEHKNAMMTELQANSEKWRYCWLFEVGSMRNSHLKTVRKLW-RDSARMFFGRGAVMAKALGTTAAEEHKLGLSKLATQ-IGQVGLFFTDQEVIEWFADFDFARAGNTATRTVILPVGFPHNEEPQLR-KLGLTTSMAKGVPSLHKLCEKGKALTSEQAQLLKLTMVTFRVA-LLARW Ganpr1 MPKSKRQKIVRLTKTKRVTREAKEQLVEKIQQNLDAHTFLWIYAVDNMRNSYLKDVRADW-KSKGRFFWGRNRVMAKALGESPESEHAENVHEIAKR-LGNVGLLFTNDQVTSYFSSFDYLRSPTTAPRTVVLPAGLPSTLEAHLR-KLGMPTRLVNGQVVLYEVCQEGQPVTPEAAQVLQQMEAEFKIR-PVCYW Gloin1 -----------------------------------------------MRNTYLQQIRADW-KDKGKLFFTKNKIIIKALGRDEQEEQELNLSKFSQE-LGNAGILFTNDDVRSYFSKTDYARAGGLVDQDIVIPAGVIPTQKPILE-SLGMSIRLEQGFLVLHTICKYGDQLTVEQAHMLKQLLAIFRLI-PTHYY Hisca1 MPVSKRARVVHESKVKKSHKEQTRRLFANIQTAVTQYDHLFLFSVDNMRNTYLKDVRSEF-ADS-RLFFGKTKVMAVALGNTPETACAPNLEKLAPY-LGAVGLLFTSQSVLDFFDSFDFARAGAVAPRSFTIPSGLSHTIEPTLR-KLGVPTRLIGGKVVLYQVCKAGETLDSRQTTLLKIFVAEFRVE-MKAQW Klula1 MPRSKRSKLVTLAQTKKG-RENKERIFDEVREALDSFRYAWVLHLEDVRTPVLQEIRSSW-VGS-KLIMGKRKVLVKALGEKPEEEYKENLAKLCKH-CGVTGLLFTNDVVEDYFKAYDFSRPKSKAPLSFTIPAGMIHSLEPTLRNKFKIPTKIKNGKITIYLVCEKGKTLDVTQALILKQFAAEFRVK-VAAYY Lacbi2 MPKSKRSKVVSLTKVKKT-KEHKNAMINELQTNAEKWRYCWLFEVGAMRNSHLKTVRKLW-KDSARMFFGRGAVMAKALGTTLEEEHRVGLHKLAKQ-IGQVGLFFTDQEVIEWFADFDFARAGNIASRTVILPLGFPHNEEPQLR-KLGLTTSMNRGVPTLHKLCTQGKVLTAEQAQLLKLIMVVFRVG-LIARW Lenti61 MPKSKRAKIVSLTKVKKT-KEHKSALIQEVQENADKWQYCWLFEVGNMRNAHLKTVRKLW-KDTARIFFGRGAVMAKALGTTPEEEHRPGLHKLASQ-IGQVGLFFTDQEVIDWFADFDFARTGNRASRTVVIPSGFPHNEEPQLR-RLGLRTRMERGVPTLHTVCQKGKTLSPEQTQLLKLVMVKFRVG-LRARW Malgl1 MARTKRAKVVSLTKTAKT-RENKENFVENVREAANQYAYIWIFAVSNMRNAYLGEVRRLW-TGS-KIFFGKLRVIAKALGETTEEEIRPGLGQVSQR-LGNVGLLMTDAEVLDWCNDYEFARMGNRATETIILPPGLPHNLEPQLR-ALGMPTQLKRGEPTLFTVCRKGEKLSAEKAQILKHLMAHFRLI-PLAYW Mellp23 MPKSKRATIVHLTKTKKT-KEAKGKLIDDLKAATDEFKYAWLFTVDHVRTTYLQEIRSAW-KPA-RIFLGRNAVMRLALGSTPENEHMPGTGVLGRL-LGDTGLLFTDKVVIEWFDDFDYARKGNVATETVELPAGAPGAMEPHLR-ALGLPTTLQRGVPTLYKVCSEGATLSTQQAGLLKTLQAKFKVV-LRNVW Mnele MPKSKRDKVVPLTVTKKS-YDTKKELVSEIQECCDKYAHIFLIEVHNERNNLLKEIRESW-KHS-RLFLGRNKVMAFSLGRTVETEYKKDLHKLAKA-LRKRGLLFTNEDVKDWFKSHCYARSGSIATETVVLPDGFPHSMEPQLR-QLGLPTRLKDGVIVLHTVCTAGKVLNTQQAVILKHLMAEFQIE-LMSHW Monbr MPKSKRAKVVSLTQTKKG-LETKTQLVEQIQQCLDEYKAAYIFSVDNMRNAKLKDVRLAW-RNS-RFFFGKNRVMQRAFGFSAQDEYKPNTHLISEH-LGNVGILFTNEDVVSWFETFDYARSGNPATDTVKLTAGFAHTMEPQLR-ALGLPTSLKRGIVTLYLVCNKGDSLSPEQARILKLFMAEFKIK-LTSAW Morel2 MAKSKRNKIVPLTQTKKG-RAGKDALYEQIRESSDLYKYIWIFSVENMRNTYLKTVRSEW-KTS-RFFFGRTKVMAKALGTSPEDEHKDNLHKLSEQ-LGHVGLLFTNEEVREFFANYDFARSGIKATSTFVVPAGFPHNMEPQLR-SLGMPTVLNNGIVTLYRVCKEGQTLTPEQAQLLKLFMAEFHVT-LKSYY Mucci2 MPKSKRSTVVSLTQTKKG-REGKEKLIEDIHQCVDNYDYLYLYSVKDMRNTYLKEIRHDF-KDS-RFFYGKNRVMAKALGTTAEEEYKEGLSAIAKE-LSEVGLLFTNEEVKTYFAEFDYARSGAIATQTITLPEGMPHNMEPLIR-SLGMPTVLKNGIVTLYTICMEGETLSTNQAHLCKLFLAEFSVD-LISYY Mydma MPKSRRNKVISLSKTKKE-FQTKKSLVDEIRKCCDEYTSLYVFSVENMRNDKLKDVRQKW-KTS-RFFYGKNKVMAFGLGRTKEIEYKENLHKISSE-LGNVGIMFTNQVVKEWFEKFDYARSGNTATQTVTIPEGFQYTMEPVLR-ALGLPVILQKGVIHLYTVCKEGDTLSPEQCKVLKLFLAVFHIT-LKCVW Neucr2 MPKSKRAKVYNLTQVKKN-REQKEKLFENIRECIPNYQHCFVFSIDNMRNNYLKDVRKEL-NDC-RIFFGKTKLTARALGTTPEDAQADGLDKLSKY-LGSVGLIFTNSEIKDYFVNLDFARAGSVATRTITIPSGVSHTLEPELR-RLGMPTRMVKGKVCLYVICKEGETLDSRQTRLLKLFLSEFRVK-LLAYW Orpsp11 -----------------------------IQKCVDKYQYIWVFNIDNMRNYYLKEVRSEL-NTS-RFFLGKNKIMAKALGNTPEEEYKPNLSKIAER-LGNVGLLFTDSEIQNYFENFDYARSGFIATSDFVVPAGFPSNMEPQLR-KLGLPTALKTGVVTCYTVCKKGDTLTPEQAQLL---------------- Pench1 MPRSKRARVVHESKTKKDHKEQTRRLFANIRECIEEYDHLFVFAVDNMRNTYLKDVRTEF-ADS-RVFFGKTKVMGKALGTDVESEAAPNLRKLTPF-LGAVGLLFTSESVIEYFETFDFARAGTEATRSFTIPNGVSHTIEPALR-KLGVPTRLVKGKVMLYPVCKEGETLDSRQTTLMKMFSSEFKVD-LKAYW Phybl2 MPKSKRVSVVALTQTKKG-REGKEKLIEEIQKSVDQYSYIWLFSVKDMRNTFLKEVRNDF-KTS-RFFMGKNRVMAKALGTTPEEEYKPELSKLAEQ-LKEVGLLFTNEEVKNYFEEFDYARSGVVASQTIVVDEGMPHNMEPLLR-SLGMPTLLRNGIVSLYTICKVGDTLSTNQAHLLKLFLAEFRIQ-PICCY Picst3 MPRSKRSKLVTLAQTKKG-KENKTRIFDDVRSALDEFQFVWVLQLDDVRTPVLQDIRSDW-SGS-KLILGKRRVLEKALGDTPEEEYKDNLHKLSKT-CGLPGLLFTNETVQAYFTAYDYSRAKSKAPIDFTIPEGMSHSLEETLRNKLKVPTKIKAGKITMYVVCHKGETLDVRQALILKQFASEFKVN-VVAYY Plicr1 MPKSKRNKIVSLTKVKKT-KEQKNVMITELQENADKWKYCWLFEVGAMRNAHLKTVRKLW-KDSARIFLGRGAVMAHALGTTVETEHRQGLHKLAQQ-IGPVGLFFTDQEVLDWFDDFDFARAGNLASRTVILPAGFPHNEEPQLR-KLGLSTTMTRGVPLLHKLCEKGKVLTSEQAQLLKLIMVVFRVR-QKARW Polpo MVQSKRSKAVSLTKVKNP-NQKKSKLISTVRECVEEYSDIYLISFDNVRNNHLKQARADW-SNS-RFLFGKKKVLSIGLGRADSDEQKPGLSKLSQN-LGECCLFFTNDTVL------DFARAGFEPEETITLKQGMTHTQEPYLR-RLGMPTSLKNGVIILYDLCEKGTVLTPDQARLLQLFISEFKFI-LLGYW Pucgr2 MPKSKRQTIVHLSKTKKT-KEVKAKLIEQIKEASENFQFVWLFTVDHVRTAYLQDIRSSW-KPS-RIFMGRNAVMRLGLGSKEEDEHMPGLGAIGKL-LGDTGLLFTNKVVVEWFDDYDYARKGNLATETVELPAGAAGALEPHLR-ALGLPTTLQSRIPTLHVVCKEGEKLDTNQAGLLKTLMAQFKIV-LSHVW Punst1 MPKSKRNKVVTLSKVKKN-RDHKNALVAEVQGAVDKWKYCWLFDVGNMRNAHLKTVRKLW-KDTGRLFFGRGAVMAIALGTTPESEHKTGLHHLASR-IGQVGLFFTDAEVTEWFGDFDFARSGNVATRTVVLPEGFPHNEEPQLR-KLGLHTVMKRGVPSLHTVCTKGKVLTPEQAQLLKLVMVEFKVG-LRAYW Rhior3 MPKSKRSTVVSLTKTKKG-REGKEKLINDVQECVDNYSYLYLFSVKDMRNTFLKEIRNDF-KDS-RFFYGKNRVMAKGLGTSPETEYKEGLSGIAKD-LNEVGMLFTNKEVQSYFDEFDYARSGAIATQTVTLPEGMPHNMEPLIR-SLGMPTSLKNGIVTLYTICTEGETLTTNQAHLLKLFLAEFKVD-LISYY Rhoto1 MPRSKRDRVVALTQTKKG-KEAKGRLIEEVREQAEAFKYLWVFEVEHMRNNSLQEVRTAW-KGS-RIFLGRNAVMRKGLGATPEDECRLGVHKIANM-LGNRGLLFTDEVVTEWFESFDYARTGNTVEEGFELPAGAPHSLEPQFR-KLGMSTSLLKGVPTLHVVCKPGDTLNPNQVNLLKLFFATFQIVPLLGVH Rozal11 MPKSKRSKSVVLTQTKKG-NDNKINLIEEVRKCIDEYPIIYLIKVKNMRNQYLKEVRTDW-KGS-RFFFGKNRVMAKALGTTEDEAIHENLHILANK-LGDVGLLFSSEEAKNYFEGKDYARTGQIATETVVLPSGFPHSMEPQLK-SLGVTSSLKNGVVINYTICKEGDVLTSSQARLLKMFMSEFRVD-VLGYY Sacce1 MPRSKRSKLVTLAQTKKG-RENKERIFDEVREALDTYRYVWVLHLDDVRTPVLQEIRTSW-AGS-KLIMGKRKVLQKALGEKREEEYKENLYQLSKL-CGVTGLLFTDNTVKEYFKSYDYSRPNTKAPLTFTIPEGMIHSLEPTMRNKFEIPTKIKAGKITIYLVCTEGEKLDVRQALILKQFASEFKVK-VSAYY Salro MPKSKRAKVVSLTQTRKG-LQTKKALVQQIHDACDEFARVFIFSVENMRNAKLKEVRTGW-RDS-RFFFGKNKVMSIAFGLDPESEYRTNMHEISKR-LGNVGVLFTNEDVEKWFKTYDYARAGNPSTQAVRLMAGFSHALEPQLR-KLGLPTSLKRGIVTLYTICEKGVTLSPEQARLLKLFMATFRIN-LLAVY Schco3 MPKSKRAKVVSLTKVKRT-KEEKGELITQIQENVEKWQYCWLFEVGNMRNAHLKTVRKLW-KDSGRLVFARSTVMAKALGTTPESEHRPGVSKLARQ-LGQVGLFFTNSEVTEWFADFDFARAGNTAPRTVVLPAGFPHNEEPQLR-KLGLTTYMNRGVPSLHKICEAGHKLTAEQAQLLKLIMVTFRVG-LLARW Schpo1 MPKSRRSKVLTLAQTKKG-HEGKAALFSGVQQSLDSFDYMWIFDVTNMRNTYLKRIRDDW-KGS-RIFMGKTKVMAKALGHTPEEEHAENVSKLTKL-LGAVGLLFTNDEVIGYFESFDFARAGAVAPFTHVIPAGLTHTLEPQVR-QLGMPTVLKNGVVTLFPLCTEGQQLDSRQTRLLKLFAAEFKVG-LLGYY Sorma MPKSKRAKVFNLTQVKKN-REQKEKLFENIRESIPNYQHCFVFSIDNMRNNYLKDVRKEL-NDC-RIFFGKTKLTARALGTTPEDAQADGLDKLSKY-LGSVGLIFTNQEIKDYFVNLDFARAGSVATRTITIPSGVSHTLEPELR-RLGMPTRMVKGKVCLYVICKEGETLDSRQTRLLKLFLSEFRVK-LLAYW Sphar MPKSKRNRIVTVSATSKG-IELKSDLVKQIKDSVDEYSNLFVFTVQNMRNAKLKDVRNEW-SHS-RFYFGRNKIMAKAIGDTVETEVAENIHKVSKQ-IGDVGLLFTNEEVTEWFDQYDYARAGCVADREFVIKAGFPHNMEPQLR-SLGLKTSMKKGVVTLYVVCKFGQTLSPEQCRLLKLFMVQFQIT-LKCHW Spipu1 MPKSKRAKVVHLAKTKKT-RLHKTALVESIHTALTTHSHIYVFSVANMRNTFLKDVRAER-SND-RFFFGRNKVMAKALGTTAEEEEREGLHLISER-LGDVGLLFSNEDVKKFFDDYDYARSGCVATETVQLPEGFPHNMEPQLR-ALGMPTSLVNGVVTLYTICKAGDVLTPDQAQLLKHFQADFQVK-ITCHW Sporo1 MPRSKRDKVVALTEVKKG-KEVKSALIDSVRESADQFSHVWVFQVEHMRNNLLQEVRSAW-KGS-RIFLGRNAVMRKGLGSTKEDECRLGVSKIANM-LGNRGLLFTDQVVLEWFESFDFARTGNVVQESFSLPEGAPHSLEPQFR-KLGMSTSLMKGVPTLHTVCNKGDTLNPNQVNLLKLFFA----------- Stehi1 MPKSKRQKLVSLTKVKKT-KEQKGAQLTAIQENLEKWKYCWLFEVGNMRNAHLKTVRNLW-KDSARMYFGRGALMAKALGTTPEDEHRPGISQLTPQ-IGQVGLFFTDDEVIEWFKDFDFARAGNRASRTVILPAGFPHNEEPQLR-KLGLTTVMKKGVPTIHKLCEKGKVLTPEQAQLLKLTMIEFRVG-LKARW Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MPKSKRAKVTTLSKTRST-KASKASLVNELRSQVDNFPHVWLFSVGDMRNEGLKDVRGQW-RGTGRFFFGKGKVMAKALGDSPEDEYQPDLHLLARC-IGPVGLFLTNDETREWFETWEYARMGAKATQTITLPAGFPHSMEPQLR-ALGLSTTLVRGVPSLHILCQQGEKLSSEQCRLLKLLMAEFRIL-LGSRW Trire2 MPKSKRAKVFHLTQVKKT-REQKDQLFQNIREQVPEYQHCIVFNVDNMRNNYLKDVRREL-SDS-RLFFGKTKLMAKALGQTAEEAIVPGIEGLAPH-IGTVGLLLTNDSVLDYLSGIDFARAGVAASRSFTIPPGLTHTIEPELR-RLGVPTRMVKGKVVLYVVCKEGEILDSRQTRLLKLFLSEFRIK-PLAYW Umbra1 MPKSKRSKVVSLTKTKKG-RGGKDTLFEEVRECVDKYAFLWVFSVDNMRNTFLKEIRSEF-KDS-RFFLGKNKVMAKALGTTVEDEYKENLRQVSKL-LGDVGVLFTDEEVKEYFNDYDYARSGVVATETVTIPEGMPHNMEQHIR-NLGMPTTLQNGIVTLYEICRLGQTLTTNQAHLLKLFLSEFRVK-LLCYY Ustma22 MPRAKRAKVVSLTRTKKT-KEDKANLIDKVRDAAQEYPYVWILGHHSMRNNYLKEVRDLW-KGS-KIFFGKLKVLALALGMTEEEEVRTGISGISQR-LGDVGLLFTEAEVIDWFKDYDFARGGSKATETIELPEGLPHPVEPQLR-QLGMPTELRRGIPTLYVVCKEGQTLTSNQAQILKHIMAAFRLI-PLAYW Walse1 MPKSRRNKLVSLTETKKT-REHKEALVDLIRQAADENKYCWIIEAGDMRNSSLKDVRAAW-KGTGRLFFGRLKVMAIALGTTPETSHKPELYKLSEH-LGSAGLFFTNNEVKEWFDSFDFARTGNVATQTIELEEGLPHTLEPSLR-KLGLSTSLLKGVPTLHTVCKEGQTLSAEQAQIIKHLMSNFKLQ-VKALW Zygro1 MPRSKRSKLVTLAQTKKG-RENKERIFDEVREALDTYKYVWVLKLDDVRTPVLQEIRTSW-AGS-KLIMGRRKVLEKALGTTKEEEYRDNLHKLTSH-CGVTGLLFTDDTVKGFFETYDYSRPNSAAPLTFVIPAGMVHSLEPTMRNKFNIPTRIQKGKITLYKVCEEGEKLDVRQALILKQFLAEFKVK-VAAYF [Cluster1772.fasta_al_trimmed; alignment length = 87] Allma1 KAWDLAYSGAKS-IPMNLIMMYMTGNSLQIFSIFFTV-MMFWNPIKSLVNKVFLPLKLAFVGLQVLLALYKCQQMGLLPTTESDWLA Ashgo11 KAWQLAFQPSKA-IPMNFFMSYMSGTSLQIIPIMTAL-MLLTGPVKSVVRSTFKGLMCLYVFFQMAIGLQKLNAMGLLPNKHSDWLA Aspfu1 KAWEIALAPLKQ-IPMNAIMMYMSGNSLQIFSIMMVF-MLFKGPIQGLTNTVFAKFKAVYVLMQLGLGIWKVNAMGLLPTTRSDWLA Aurde31 RAWDVAIAPAKQ-LPMQFFMLYMSGSTIQIFSIGILV-MLLFSPFTAVINSTFAPYKLAFVACNVALGLWKCKQVGLLPQGTGDWLP Batde5 KAWDTALAPAKS-IPMNALMLYMSGNSIQIFSILITV-MLLFNSAKSMVSQAFERFMTAFFLIQLALGVWKCGAMGLLPTATSDWLA Botbo1 RAWDLAMAPGKS-LPMNAFMLYMSGGGVQIFSIGILA-MLLINPIKAFINTAFAPLKAVYVLCNLALGLWKCSTLGLLPTGTADWLA Botci1 ---------------------------------MMVV-MAFKNPLMGLTNQAFERFKLAYVACQLALGIWKVNGMGLLPTTRSDWLA Caeel RVWDTAMGPAKS-LPMNMFMMYMAGGGVSIFPIMMVG-MMVFRPLKALVNSTFKPLKLIFCLGNIGLAIYKVHTMGLLPNTPSDWLE Canalb1 KIWELAIGPAKS-IPMNLFMSYMTGNSLQVISVTMTL-MLLWNPIKAITNPTFSKLKIVFIICQMGIGVYKLYKMGLIPHQEADWLA Cangl KAWEIALQPAKS-IPMNFFMSYMSGTSLQIIPIMTAL-MLLSGPVKSIIRETFKPVMILYVAFQMFIGLKKLNDMGLIPNKTSDWMA Capow KAWEMALAPAKS-VPMNGFMMWMAGNSIHIFSIMITV-MMLITPVKAITGTTFAKLKLVFILANIGMAMYKFSVLGLLPTSPSDWLS Catan2 KAWNIAYSGAKS-LPTNLLMMYMSGNSLQIFSILITV-MMFWNPVKSLIDKAFAPIKLTFVAIAMLIALYKCQQMGLLPTSDSDWLA Cioin KSWEIAVGPIKG-LPMNIFIMYMAGNTISIFPIMMVG-MMFFRPTQALIRTTMRMLTFLYFLGNLALAVYKCNSMGLLPTHASDWLA CocheC53 KAWEVAIAPAKQ-LPMNAFGMYMTGNTLQIFSVFMVF-TLFKTPVLAVLQRTFAPYKLVYIACNLALGIWKVNAMGLLPTTRSDWLA Coere1 KAWEVAISPGKS-LPMQAFMAWMSGTSVSIFSILITG-MILMSPLRAIVQQTFAGLKAAFVAINILFGVYRLSIMGLLPTTSSDWLA Conco1 KAWEIALGNAKN-IPMNAIMLYMSGNGIQIFSIVITF-MLLFNPIKDVVNTVFNRLKLVYILINMGMGLWKCSSMGLLPTSPSDWLA Conpu1 RAWDLAIAPAKS-LPMQAFMLYMSGGGVQVFSLGIVF-MLLLSPIKNVMNTAPASAKTVYVICNLAVGLWKCRSMGLLPTGTGDWLA Copci RAWEFATGPAKQ-LPMQAFMLYMSGGGVQIFSMGIVF-MLLMTPFKNVMNDAFAQFKLLYIACNLGVGLWKCKSMGLLPTGTGDWLA Croqu1 KAWEIALAPAKQ-VPMQAFMMWMSGSGVQIFSVMMVY-MLIKGAITASVHNVFKPFKLSFLACQLGLGLYKVNTMGLLPTRLSDWIM CryneH991 RAWDLALSPAKS-LPMQAIMLYFSGSGIQIFSLGMIF-MLLTQPISAVIFQAFEPFMVLYVVCQLALGLYKCSSMGILPTGSGDWLH Crypa2 KAWEVALAPIKS-LPMTAIMMYMTGNSLQIFSIMMVF-MAFKNPIAGLTNQAFERFKLAYVAMQLAVGIWKVNSMGLLPTTRSDWLA Debha1 KAWEIALGPAKT-IPMNLIMSYMTGNSLQIIPIMMTL-MLFWNPLKAITNANFKNLRAVFVICQMAVGIWKLYNMGLIPNSEGDWLA Dekbr2 KIWELAIKPVKS-VPMNALMMYMSPNSIQIISIMMTV-TLFFNSLRDIVNRAFANTKTVYVISCLLLGIWKLNSLGLIPNRTSDWLG Dicdi KGWELAKSPAKN-IFMTGFFLWMIGNGINIFTMPVII-YAVINPVKAITNTMFSRFKLTFVVIQLSVTLYKCSSMGLLPITPSDWIS Dmel KSWDLALGPLKN-IPMNLFIMYMSGNSISIFPIMMVG-MMLIRPIKAITQVTSKMARIVYFLGNVALALYKCQSMGLLPTHASDWLA Enthi QAFSTALGPVTSNIPM-LLMAWLTGSSVSYINLMFTA-TLINNFINSLVNEVFKKYKVVYLIACLGIAVYKFSKMGILPNRDSDFLP Falba RAWGLVRDSAFQ-LPVQFLLVWFTVNSVSLFQIVLLI-GLLRSPILGVAPKLFSDILTAYIFLQLGFCLLKIHKLGLLPTSASDWLQ Fomme1 RAWDLAISPAKQ-LPMQAFMLYMSGGGVQIFSMGIVF-MLLFSPFKNLINSVFAQFKSVYFLCNLALGIWKCRSMGLLPTGTGDWLA Fusgr1 KAWEVALAPVKG-LPMTAIMMYMSGNSLQIFSIMMVF-MAFKNPLMGLTNQAFERFKFVYVVCQLGVGIWKINAMGLLPTTRSDWLM Galma1 RAWDVAIAPAKS-LPMQAFMLYMSGGGVQIFSIGIVF-MLLLSPFKNIMNEAFAQYKIVYILCNLGVGLWKCRSMGLLPTGTGDWLA Ganpr1 KAWEAALGPAKT-VPMNAFMLWMSGSGVQIFSIMMLY-MLFSGGVQGIVTQTFERFKIIYVALQIALGVWKLSSMGLLPTAQSDWLA Gloin1 KAWDAALSPGKN-IPMNAFMLWMSGNGVQIFSVMITG-MLFFQPIKALIDSVFERYKLVYVILQMALGLYKCSSMGLLPTATSDWLA Hisca1 KAWELALAPTKQ-LPMNAIMMYMSGNSLQIFSIMMVF-MLFKGPIQGLTNSAFAKFKVV--------------------TTRSDWLA Klula1 RAWQISSEPLKS-VPMNIIMSYMSGNSLQIIPIMTAV-MLVSNPIKSIVKSKFQHLMIMYVIYQMGIGLHKLNSMGLFPTTSSDWLA Lacbi2 RAWDVALAPIKS-LPMQAFMLYMSGGGVQIFSMGIVF-MLLLTPFKNIINEAFAQFKLVYIACNLAVGLWKCRSMGLLPMGTGDWLA Lenti61 RAWDLAFSPAKS-LPMQAFMLYMSGGGVQIFSMGIVF-MLLSSPFKNLINTAFAPFKIAYVICNLALGLWKCRSMGLLPMGTGDWLA Malgl1 KAWELALSPTKT-LPMNFMMMWMSGSGVQIFSMMVVA-MMITNPLKGITTQVFAPYMLAFIACHVAMGIYKCWSMGLLPTESSDWLA Mellp23 KAWDLALSPAKQ-IPMQAFMMWMSGNGVQIFSVMMVY-MLIKGAITSTVNQVFKSFKLSFITFQLGLGLYKVNTMGLLPTRLSDWIM Mnele RSWDIALVPLKQ-VPMNLFLMYMIGNTLSLFPIIMTV-MMFKSPFSSLYKTTFQKLKMVFILSNIAMALYKCNAMGLLPIHPSDWIA Monbr LAWKVVEKQVYQ-LPMTLFMMYMMGSSITIWTFGFLG-YLMYNPIRSLINNEFKRFKLAYTAVTVALGAWKCSGMGLIPSSQADWLE Morel2 KAWDVALAPGKQ-LPMQAFMLWMSGNSVQIFSVAITA-MLMFSPIRALMSQVFERYKLTFVALQILFGMYKLNAMGLLPTSHSDWLA Mucci2 RAWDVAMGPAKS-IPMNAIMIYMSGTSLQIFTVMVTA-MLFFNPVKAITQQTFSRFKLAFIGLHILLGVYKVNAMGLLPNTASDWLA Mydma RSWNIATGPAKQ-IPMNLFIMYMGGSSISIFPIMILG-MMIFRPIKAMYKTTFKMFKIAWFLGNIVIALWRCHSMGLLPTSPSDWLA Neucr2 KAWEVALAPAKN-LPMTLIMMYMSGNSLQIFSIMMVF-MAFKNPIMGLTNQAFERFKAAYVLMQLAVGVWKINSMGLLPTTRSDWLA Orpsp11 ---------------------------FKEFE------------------------KLTYIALSLLVGLYKCASLGILPTTTSDWLT Pench1 KAWEIAIAPSKQ-IPMNAIMMYMSGNSLQIFSIMMVL-MLFKGPIQGLTNAAFAKYKVVYMLMQLCLGIWKVNAMGLLPTTRSDWLA Phybl2 RAWDVAMSPAKN-IPMNAIMIYMSGNGVQIFSVMITF-MLFFQPAKAILNQTFERFKLTYIGLQILLGVYKINNMGLLPTTTSDWLA Picst3 KAWELATGPAKS-IPMNAIMSYMTGNSLQIIPMTMTL-MLLWNPLKAITNDTFKGLKLGFVFFQMSIGIYKLYTMGLIPNTEADWLA Plicr1 RAWDFAIAPAKS-LPMQAFMLYMSGGGVQIFSMGIVF-MLLLTPFKNLINTAFAPFKLAYVACNLGVGLWKCRSMGLLPTGTGDWLA Polpo KGWEVAKSPAKS-IFMTGFLLWMIGSGISIFTMPVII-YSVINPIKAITNNLFSRFKITYIAIQLAVALYKCSSMGLLPITPSDWIS Pucgr2 KAWDLALAPAKQ-VPMQGFMMWMSGTGVQIFSVMMVY-MLIKGAITACVNTTFQPFKLTFIACQLLLGLWKVNGMGLLPTRLSDWIM Punst1 RAWDLAISPAKS-LPMQAFMLYMSGGGVQIFSMGIVF-MLLLSPFKNLINDAFASFKLAYVACNLALGLWKCRSMGLLPTGTGDWLA Rhior3 RAWDVALAPAKS-IPMSLFMMYMSGNSLQIFSVMITATMLFMQPIKAIAQETFSRFKLSFIGLQILLGVYRVNSMGLLPNTTSDWLS Rhoto1 KAWELAFAPAKN-VPMQAFMMYMTGGGIQIFSIMSVW-FLFKQAFGGMVQQVFAPFKVVYVLCQVAVGLWKCRSMGILPDSAADWAP Rozal11 KAWDAALAPGKS-IFMTLFMLWMSGSSVQIFSLMITG-MSLYNPIKALLNNIFSAFKVTFAFFQLLIGLYKCSNLGLLPTSTSDWLS Sacce1 KAWQIALQPAKS-IPMNIFMSYMSGTSLQIIPIMTAL-MLLSGPIKAITRSAFKPVMFMYIVFQMYIGYRKLNSMGLIPNAKGDWLP Salro LAWQVATRPMQG-LLMNFFMLWMMGSSVNLFTFPMLG-YMVYSPLVALISTEFEKLKIVFALGQIGLAVYKCSGLGLIPTTQGDWLE Schco3 RAWDFAIAPAKS-LPMQAFMLYMSGGGIQIWNLGIVF-MLMLGPLQALINQAFAPFKLAYLACNIGVGLWKCRSMGLLPAGTADWLP Schpo1 KAWELAYSPLKQ-IPMNAILAYMSGNSLQIFSIMTTL-MLLVNPLKAITGSAFTPFMGAYILFQMGIGVYKLQRMGLLPTTTSDWLA Sorma KAWEVALAPAKN-LPMTLIMMYMSGNSLQIFSIMMVF-MAFKNPIMGLTNQAFERFKAAYVLMQLAVGVWKINSMGLLP-------- Sphar KAWDLAKSPVKT-LPMNAFMMWMSGSTVHIFSLMIVG-MTAMGPLKGIAGQ------------------------------------ Spipu1 KAWDAALAPGKS-IPMNAIMLYMSGNSIQIFSVLVTV-MLLWNSIKAIVNTVFDRFKLAYIVLQLALGVWKCGAMGLLPTAHSDWLA Sporo1 KAWEVALAPAKS-VPMQAFMMYMTGGGIQVFSVMSVW-FLLKQAVGGMVENVFAPFKLVYLLCQLAVGLWKLNSMGLLPTHESDWIA Stehi1 RAWDFAISPAKS-LPMQAFMLYMSGGGVQIFSMGIVF-MLLLSPFKNVINTAFAQFKLVYIACNLALGLWKCRSMGLLPTGTADWLA Tapde11 KAWEIAIAPLKS-LPMSAIMTWFSGSSIQIFSVMMTG-SLFWTPLKVLPFAVFTSLKVVFVIGQIALGLVKLQYMGLLPTTTSDWLA Thetr KAWELAMSPVKG-FFMTGFMLWMSGSSVGIFSMMMTY-MALSAPVSAMVSNVFKGLKIAYLLLQLALGLWKLKSLGLLPTKLSDLFG Treme1 RAWELALSPAKS-LPMQAIMLYFSGSGVQIFSLGIVF-MLLTSPIKAVIFSAFEPFMVVYVICQLSLGLYKTSTMGVLPTSSSDWLQ Trire2 KAWEVALAPVKG-LPMTAIMMYMSGNSLQIFSIMMVF-MAFKNPIVGLTNQAFERFKLVYVAMQLAVGVWKINSMGLLPTTRSDWLM Umbra1 RAWDVAMGPAKT-IPMNAIMIYMSGTGVQIFSVMITA-MLFWQPIKAILNQTFERFKATFLALQIGLGIYKVNAMGLLPTTTSDWLA Ustma22 KAWELAYSPAKS-LPMNAIMLYMSGSGVQIFSMMAVG-MLITGPLRGIMNSSFDRLKILFILCQIALGLYKCWSMGLLPTETSDWLA Walse1 KAWETAIAPGKA-MFTTAFMMYMSGSSIQIFSISIVF-MTIWNALKSLINTTFKPFKLAFVACQLALGLYKADTMGLLPSRPSDWIE Zygro1 KAWQIALAPAKS-IPMNFFMSYMSGTSLQIIPIMTAL-MLLSGPIKSIVRANFRPVMLVFIACQMYIGFQKLNSMGLIPNTTSDWLS [Cluster1775.fasta_al_trimmed; alignment length = 68] Allma1 RFEIELEFVQCLANPHYLH-HLAQLDKKESINYLEYL-QYWKSQEYAKLIYP-QCLFFLDLLQFRTAM Ashgo11 RFEVELEFVQSLANIPYVT-FLLTWQDPRFKAYLKYL-EYWCEPPYTQFIYP-NCLFVLKLLNLDKAV Aspfu1 RFTLELEFVSSLANPYYLS-HLAVPEAQAFAAYLAYLYSYWKTPEYAQFLHPGATLRALRLLQFRRDI Aurde31 RFELELEFVQALANPYYLQ-SLAQLAQPEFVNYLSYL-QYWKQKDYARFIYP-HALHHLELLQFREEI Batde5 RFQLELEFVQCLANPAYLQ-YLAQFDNPALINYLAYL-KYWQKPEYAKYIFP-YALHILDLLQFRKAC Botbo1 RFELELEFVQSLANPFYLQ-SLAQLADPAFIRYLEYL-MYWKEREYARFIYP-HALHHLDLLQFRDAL Botci1 RFEIELEFINAISSPHYLM-HLASLSSPPFIAYLKYL-QYFTQPPYLKFLYPGPSLKHLELLQFRRDC Caeel RFEVECEFVQALANPNYLN-FLAQFKEEYFVNYLKYL-LYWKDPQYARCLFP-QCLHMLEALQFRDSM Canalb1 RWEIELEFVQSLSNIPYVN-YLAQFNDENFINYLNYL-QYWTQPEYSKFLYP-NCLHILKLLQFRKNI Cangl RFEVELEFVQSLANIPYVT-YLLTWKDPKFKNYLKYL-EYWCEPPYAQCIYP-NALFILKLLNMEKAT Capow RFQLELEFVQCLANVQYLH-YLGQLTQTTFINYLKYL-LYWKKPEYARFIFP-HCLYFLDLLQFRTEI Catan2 RCEAELEFISCLANVSYLH-FLATFAKPEFLNYLNYL-LYWKRPEYCHLIYP-QALFFLERLQFRASL Cioin RFQVELEFVQCLSNPNYLN-FIAQFKESTFVNYLEYL-LYWKEPEYVKYLYP-QCLHMLELLQFRNEL CocheC53 RFELELEFVQCLANPVYLN-FLAQLDKPDFVAYLAYL-QYFKHPKYAKFLHPGPTLRALELLQFRHDI Coere1 RFEVELEFVQCLANPWYIN-IIAQFDKPEFINYLKYL-KYWKRPEYARFIYP-HALAFLDLLQFREDM Conco1 RFQVELEFVQCLANPWYLN-FLAQFEQKEFVNYLKYL-KYWKRPEYAKFIYP-HCLYFLDLLQFRQSI Conpu1 RFELELEFVQSLANPYYLH-SLAQLDQPAFVNYLSYL-QYWRHKDYARFIYP-HALHHLELLQFRAEI Copci RFELELEFVQALANPYYLH-SLAQLEKPAFVNYLKYL-LYWKDKDYARFIYP-HALHHLELLQFRAAL Croqu1 RFEEDLEFVQSLANPHFVQ-ELTLLASEPMINYLNYL-KYFHEPRYAIFIYP-NCLLILDLLTFRTMM CryneH991 RFQSELEFIQCLAHPQYLH-ELHILEKPPFLNYLKYL-EYWKEPQYVRFIYP-TCLVYLTLLQFRSRL Crypa2 RFEIELDFVQSLANPHYLN-HLAALQQPAFIAYLKYL-QYWRKPPYLRYLYPGPTLRNLELLQFRKDI Debha1 RWEIELEFVQSLANIQYLN-HLAQLSNPEFLNYIEYL-NYWKEPEYSKYLYP-NCLHILTLLQFRKNI Dekbr2 RWEIELEFVQSLANMQYLT-YLAQLEDPRFLNYLKYL-EYWRQPEYAKQLYP-DCLHILTLLQFRKQI Dicdi RFIMELEFIQCLSNPRYLN-YLAQFQDKAFVNYLVYL-QYWKKPEYAKFIYP-QSLYFLDLLQFRQEL Dmel RWQIELEFVQCLSNPNYLN-FLAQFKDQSFINYLKYL-QYWKEPDYAKYLYP-MCLYFLDLLQFRREI Enthi RFEYELDFLQSLANPHYIQ-YLAYLRKTDMIHFLKYL-QYWKQPNYIKFIYP-ACLYYLEQLQFRQAC Falba RFQVELEFVQCLANPQYLI-FLAHLTDPAFVRYLRYL-MYWKQPQYAKYIYP-HALYFLELLQFRYQL Fomme1 RFELELEFVQALANPFYLH-SLAQLTQPAFINFLAYL-LYWKEKDYARFIYP-HALHHLELLQFRSEI Fusgr1 RFEIELEFVQSLANPAYLN-HLASLSQPAFVAYLAYL-RYWSKPPYLKYLYPGPTLRHLELLQFRQQI Galma1 RFELELEFVQALANPFYLH-SLAQLEQPAFIHFLEYL-LYFKEKDYARFIYP-HALHHLELLQFRSQM Ganpr1 -------------------------------------------------------------------- Gloin1 RFQIELEFIQCLANPWYLN-NLAQFEDPVFLNYLEYL-KYWKRPEYAKFIYP-HALHFLDLLQFREHL Hisca1 RFTLELEFVLSLANPHYVS-HLAISDAQSFAAYLAYLYSYWKQPEYVQFLHPGATLRALRLLQFRQAV Klula1 RFEIELEFVQSLANIPYVT-YLLTWQDPKFKRYLKYL-EYWHEPEYAQCIYP-NSLFVLKLLNFEGST Lacbi2 KFELELEFLQALANPFYLH-SLAQLEQHSFINFLEYL-LYFKEKDYARFVYP-HALHHLELLQFRSRM Lenti61 RFELELEFVQSLANPFYLH-SLAQLNQPAFVNFLKYL-QYWKEKDYARFIYP-HALHHLELLQFRTEI Malgl1 RFSRDLEFLSALSNPYYLH-QLSQFEDEAFLHYLEYL-DYFRAPRYVKYLYP-QSLYFLDLLKFRSAV Mellp23 RFEEDLEFVQSLANPHFVQ-ELTLLASEPMVNYLNYL-KYFHDPQYAVFIYP-NCLFILDLLNFRTMI Mnele -------------------------------------------------------------------- Monbr -------------------------------------------------------------------- Morel2 RFQVELEFVQCLSNPWYLH-HLAQFNQDAFVRYLDYL-QYFRKPEYAKFIYP-HCLHFLTLLQFRDQL Mucci2 RFQIELEFIQCLSNPWYLN-NLAQFKDEAFINYLEYL-QYWKQPEYAKFVYP-HALYFLDLLQFRDYV Mydma -------------------------------------------------------------------- Neucr2 RFELELEFVQALGNPLYLN-HLASLSNPAFIAYLDYL-QYWSRPPYLKYIYPGPTLKNLELLQFRQDI Orpsp11 ---------------------LAQFNKPEFINYLEYL-KYWKKEEYSKFIFP-YCLAILDLLQFRDSL Pench1 RFTLELEFVSSLANPYYLS-HLAVPDAQAFAAYLAYLYSYWKTPEYSQFLHPGPTLRALRLLQFRRDI Phybl2 RFQVELEFLQCLSNPWYLN-HLAQFKDPAFLRYLDYL-QYWKQPEYAKFVYP-HALHFLDMLQFREYI Picst3 RWEIELEFVQSLSNIQYLN-HLAQLNDENFINYIKYL-NYWKEPQYARYLYP-NCLHILTLLQFRSNI Plicr1 RFELELEFVQSLANPFYLH-SLAQLDQPAFVGFLQYL-MYWREKDYARFIYP-HALHHLELLQFRSEI Polpo RFMMELEFVQCLSNPRYLN-YLAQFQDKAFVNYLNYL-QYWKQPEYSKFIYP-QSLYFLDLLQFRHEL Pucgr2 RFEEDLEFVQSLANPHFVQ-ELTLLRSETMINTW-IP-QYFHHPDYA---LP-T-LEILDLLT-RAVP Punst1 RFELELEFVQSLANPFYLH-SLAQLNQPAFVKFLEYL-QYWRGKDYARFIYP-HALHHLELLQFRNEI Rhior3 -------------------------------------------------------------------- Rhoto1 RFETELEFVSCLANPFYLQ-SLAQFDSEPFLNYLTYL-LYFRQPTYSRFLYP-QSLHQLTLLTFRKAL Rozal11 RFIVELEFLQCLANPAYLN-YLAQLEKPTFRNYLKYL-TYWKKPEYSRFIYP-HALYFLDKLNMAAYL Sacce1 RFEVELEFIQSLANIQYVT-YLLTWKSPNFKNYLKYL-EYWCNPPYSQCIYP-NCLFILKLLNMESAI Salro RFHAELEFVQALANPRYLS-FLAQLEDTRLINYLKYL-LYWKQPQYAQYLYP-QCLYFLELLQFRKEL Schco3 RFEIELEFVQALANPFYLA-SLAQLDQPAFINYLQYL-LYWKEKEYARFIYP-HALHHLELLQFRANM Schpo1 RFEIELEFVQMLSNPWYLN-FLAQFEDEAFLQYLEYM-EYWREPEYVKFIYP-TCLHMLTLLKFRNDI Sorma RFELELEFVQALGNPLYLN-HLASLSNPAFVAYLDYL-QYWSRPPYLKYLYPGPTLKNLQLLQFRQDI Sphar RFEIELEFVQSLGDPSYLN-WLAQLQQPEFVNYLEYL-TYWRTPEYAKFIFP-HCLHFLDLLQFRDAV Spipu1 RFLLELEFVQCLANPQYLQ-FLAHFNDPAFLNYLAYL-RYWQQPQYAKYIYP-YCLHILDLLQFRSAC Sporo1 RFETEVEFVQCLANPFYLQPPLA-FFSESKLNYLQYL-EYFRKPNYSRFLYP-QCLHHLNLL-FRSAF Stehi1 RFELELEFVQALANPFYLH-TLSQLAQPAFVNYLEYL-TYWKEKDYARFIYP-HALHHLELLQFRSEI Tapde11 -------------------------------------------------------------------- Thetr RFEIELDFVQSLANPKYLE-YLAQFADKRFVAYLKYL-QYWRSPEYAVFLYP-HALFFLEHLLFRFRL Treme1 RFQSELEFIQCLSNPSYLR-GLHTLSKPEFLNYLKYL-EYWRKPEYVRFIYP-TSLVYLTLLQFRSRL Trire2 RFEIELEFVQSLANPYYLN-HLASLSQPAFVAYLDYL-QYWSKPPYLKYLYPGPTLRHLELLQFRQDI Umbra1 RFRIELEFVQCLANPWYLN-YLAQFQDPAFINYLKYL-QYWKSPEYAKYIYP-HALHFLDLLQFREHV Ustma22 AFSRDLEFLSSLANPYYLN-HLALLSSPSFKRYLKYL-DYFRHPKYVKYLYP-QALHFLDLLQFRLAC Walse1 KFEIELEFVQSLAHPFYLH-ALAQFEKPEFINYLKYL-NYWREREYVKFIYP-HCLHNLDLLMFREAI Zygro1 RFEVELEFVQSLANIPYVT-YLLTWKDPKFKNYLKYL-EYWCEPPYALCIYP-NCLFVLKLINMENST [Cluster1779.fasta_al_trimmed; alignment length = 280] Allma1 YWLISVPFVIP-DLKVGTLDSLVLLSDDLAKVDTVAEASVNKLIDTMKMLLLVVHDPDTYVKAFSWNTMKY-RVD-KPLRETVEAIQQEVSHVDTMMKTRLSTYNQCKANLTALDRKMMGNLAVRSLVDVVKKEHFVDSEYLTTLLVAVPRYKLWQDSYERITMVVPRSSQKISEDDEYGLFTVTLFQKDDFAAKCRELKFTPFNEKDLENSRKQRADLQLLRLTKTNFGEIFLHIKAIRIFVESVLRHGLPPDFFGEHR---RDKQLEKEFYAYVNFPL Ashgo11 LLLLSLPFAVP-EFKIGSLDALVLQSEELGRVDAQVHAALGKIEEALAALG-------DPPSAFRWDTRRY-KLD-RPIRDLIAELARECAQLDSDVRAAAAEHAAACSALAAADRHESGDLSVRALHDIVREEHCVDSEYLTTALIAVPQRPEFERAYETLAHVVPGSAAVLASDSEFALYAVHLFRRPAFAAACRERGCVPYSPDAVRALHQERVASALARLARTARADVRLHVLALRVFVESVLRYGLPPHFFGYLGGNAHDAALDTDYEPFVLYSV Aspfu1 YLLVSLPFPIP-EFKIGTLDALVQQADELAKLEASCQGVVAKVGDALKGVLKTVNDVDQYLRTFSWNKVKY-RAD-KPLGELIDLLQKEAASIDNDIRSKYSQYNQVKNTLATLQRKQTGNLSTKSLASVVDPRTLVDSEYIETHLVAVPAVKEFLKTYETVAMVVPRSATLVASDDEFTLYAVTTFKKPEFVHRCREHKWIPYVEGGKEEEQKEVERVETLRLGRTAWSEAVIHVLVLRVFVETVLRYGLPLDFYSYLAGNADDPH-A-EYTAYVYYEF Aurde31 SWLIAVPIDIP-EFKAGTLEVLLSLSEELPKMDAVFTQAVAKIVDTIRNLLVLVNDVDSYLLSWKWNASRY-SPQ-KSARDTVDTLQKEMTSIDNVMKSKLTNYNLAKGSLVQMQRKKTGNLSVRALADVVKKDDFLDSEYMETVLVAVPKIKDWNLKYERLAMVVPRSSKKIAEDDEYTLFSAVIFKRDEFAQKCRENKFTLYSEEAVEKQIAELQKAELLRLSRTNFSEAFVHLKVVNAFVESALRYGLPARYFAYLKPAS---DVEQEYYDFVLVEI Batde5 IWFLSAPYTLP-DFKVGTLDTLVVLSDDLAKTDQMLEASVVKIADGLKGLLLVIGDIETYLKSFQWNSMKY-RSD-KTLREIADTIIQEVSSIDTLMKTKSQVYSQVKGVLQGIQRKSSGNLAVRTLGDVVKKEMFVDSEYMATLLVAVPKTKEWLSDYETLTMVVPRSTVKIVEDDEYVLFSVTLFQREEFSNKARERKYIVWDPERLSADKKQLADLTLLRLSKTNFGELYIHIKALRLFVESILRYGLPPNFYANAD---ADAGMEKDYCPAVIFPI Botbo1 TWLIAVPLLIP-SLKTGTLDLLVTLSEELPKHDTFFTSAVAKIVDTLRNLLILVNECDEYLLDWRWNAGKY-GSQ-RSLRDVVDSLVKEMTSIDNVMKNKLNSYNLAKGSLTQMQRKKTGNLSVRSLVDVVTKENVIESEYLETVFVAVPKVKEWNSSYERLTMVVPRSSTKIAEDSEFTLFAAVLFKKDDFAQKCRENKFILYDEKSLGKQREELEAAELLRLSSINFSEAYVHLKVVRLFVESVLRYGLPANYLAHLTPQS---DIDQEYLDFVFFEV Botci1 YLLVSLPFKIP-EFKIGTLDALVGQADDLAKLESACQGVVAKVGESLRNLLKTVNDADQYLRTFSWNKVKY-RAD-KPLAELIDSLQKELVSIDNDVKGKMNQYNQVKTNLTTLQRKQTGNLSTKSLTPVVDPKLLVDSEYLETHLVVVPTKKDFLKTYETISMVVPRSSVEVTHDDEFTLFAVTTFKKADFQHKCRENKWTPYVEGGKEVERKEAEKVEALRLGRTGWSEAVIHVLTLRVFVETVLRYGLPLDF---------SPS---------FY-- Caeel YWLISVPYLIP-DLKVGTLDQLVGLSDDLSKLDTSAEAVIRKLVQYFTEVLLVIGNMKTYVTKFQWEGAKY-PLK-QSLKVLSEIIGKQISQIDNDLKVKSLTYNNLKNALASMDRKTVGSLLTKDLADLVKADDFVNSEYLQTVIVVVPKVKEWEQKYATLSMVVPGSSKLLTEEGEHALYTVTLFKKDEFKNTARENKFIVYDEETLKAGRTERDKLPLIRWLKINFGEIFIHIKALRVFVESVLRYGLPVNFYIHLDGSATLEDSVNEYYPYVFFKL Canalb1 YLILSLPLKIP-DFQSGTLDSLVQESEELNKIDHQLGSSVNKVVEILNSINRIVQSIFDYIENFQWNSSKY-RLD-KPISQLVKMISQEAITLDNDVRTSYQSYQSAKSNFLAADRKKNGDLSIKSLHEIVKPEQFVDSEHLTTILIAVPNLDDFHKNYETLTFVIPRSAELIAKDQEFHLFTVTLFKKQEFINNAREHRWHPYSEEILNELRKEFDLTDLIRLTKTAYSDIMFHIKIIRTYVEAVLKYGLPPQFFNYLGGNGNSSNLDTEYQPFVLYEL Cangl FFLVSLPFKIP-EFKIGSLDNLLVESEDLSKIDNQVGSSVSKIVEILSGMNIPINNIPEYLEHFEWQTRKF-KLD-KSIKELMSNLSDEASQLDLDVRATYTNYTNAKSNLAAAERKKTGDLSVRSLHDIVKSDDFIDSEYLTTVLIAVPKKADFEKTYETLSNVVPGSAGIIAKDDDYILYNVHLFKRQEFTTAAREKKFIPYSEELIDQLKREHDSAQLVRLAKTAFVDVFFHIKALRVYVESVLRYGLPPHFFGFLGGNADDTSLDADYEPFVFYHI Capow FWLVAAPFNVP-DLKVGTLDALVQLSEELQKHEMFADSVVRKLAQLVSDLLLVIGDPAAYLKNFNWDTARY-LTK-SSIPELTDTLTKHLSQIENGMKGKTSAYNQLRGNLQALERKATGNLLVRSLTDVVKKEHFVDSEYLTTLLVVVPKFREWESSYERITMVVPRSSKMIAEDSEYGLFTVTVFQKSDYKVSARERRFVVFDEASVEQGKKDRTNLAMIRWGKVNFSEAFAHLKAVRLFVESVLRYGLPVNFYGYLDKSAETVEVQEKFHPWVMVQL Catan2 FWLISLPFVIP-DLKVGTLDSLVKLSDELGKMDQVAEAASNKLVDLMKTLLLTVGNADDFLRSFAWNTMKY-RID-KPLREIVDAIQQEVAQIDSTMKSRTTAYNQIKSNLVAMERKQQGNLAVRSLVDVVRKEHFVDSEYLVTLLVAVPRYSAWESSYETLTMVVPRSTQKIAEDDEFGLFSVTLFQKDDFTHKCREMKFTPFNEKDLETMKRQKQELQLLRLTKANFSEVYVHIKAVRIFVESVLRYGLPPDFVGGQKKT-RDKELDKEFYDYVWFPL Cioin YWLISAPFHIP-DLKVGTLDALIGLSDDLGKLDIFAEXVCRKVSSYMGDVLLTTDDLETFMHRFQWNLAKY-PVK-LPLKSLAEISSKVVTQVDTDLRTKSQAYNNLKSNLQNMERKATGSLLLRNLREIVKKEDFIDSEYLQTLLVAVPVTEEWEKNYETLTYVAPRSSRLLYRDEEYGLYGVTIFKKEEFKTKCGRHKFFLYNERDMASDKDQLTKLPLLRWLKVNFSEVFMHVKALRVFVESVLRYGLPVNFYVGLD--SDDF-LTQEYHPYVFYKV CocheC53 -------FAIP-NFKIGTLDALVQQADELSKLSNACEGVVAKVGESLRQILKTINDVDQYLRSFQWNKVKY-RAD-KPIADLIDALQKEIQGIDNDVKSKFSQYNQTKGALAAAERKRTGNLSTKSLVNVVNPKSIVDSEYLDTHLIAVPNVKDFYQAYEELSMVVPRSANKIAQDDEFTLFAVTTFKKNEFVHKCREKRWTPYKEGGKEEEAKEADQLEALRLGRTGYSESAIHVLALRVFVETVLRYGLPLDFYSYLGGNADDQSMQ-EYTAYVYYEF Coere1 YWLISVPFLLP-ALKIGTLDTLVKLSDELSKHDTVCEATVTKFIDTLHSLTLQVDGVDQYVKTFSWNNSKY-RSD-RTLPEIVAQIAESMATIEHQLKTKLTQYNAIKNSLTTVRRKQTGNLSVKSLNGIVSREDCIQSEFLQTVFVAVPRTKDWNNSYERLTMVVPRSSKKIAEDSEYVLYSVVLFKRDEFSNKARDMRFIVYDEEAMAKDRAMAEEVNISEWLKGSFGDVIIHIKALRVFVESVLRYGIPPDFYSYLETSSEDSAF--DYTPYVFFEI Conco1 FWFLSIPVELP-DLKFGNLDTLMLLSDELVKLDQLYEQLVNKIIDTLKSTLLLVDNFDDYIKTFSWNSMKY-RTD-KSLREVTDIIIQEMTTLDTTLKTKSTQYTAIKNSLTSLNRKQNGNLSVRNLNDIVQKEHCIDSEYLTTVFVAVPKYDDWEKSYERLSMVVPRSAKKIAEDNDYGLFSVHLFKRDSYTTACRENRFIVYSETQMEEERKELDRVSLVQWCQTSFSDAVIHIKVIRVINESVLRYGLPSNYYGHLG---EDKGNDNDYVPYVRFSY Conpu1 TWLIAVPLGIP-SFKTGTLDSLIALSEELPKQDTFFTSVVAKTVDTLRNLLILVNEVDDYLFKWKWNEGRY-GVQ-RSLREIVDLLNKEVASIDNVMKAKLNNYNLVKGSLVQMQRKKTGNLSVRSLVDIVSKEHIIESEYLDTMIVAVPNNKEWNSKYERLTMVVPRSSISITSDSEYTLYSVVVFKRDEFTQKCRENKFIVFSEDEIVKQKEELAMAELLRLSRTNFSESFVHLKVVRLFVESVLRYGLPSNYFGYLSPRS---DFEQEYYDFVLFEV Copci ---------------TGTLDSLIGLSEDLTKLDGTFTATVAKAVDTLRNLLVLVDEVDSYIMSWRWNESRY-PVQ-RSLRELVDGLTEEMTSIDNALKNKVTNYNQVKGSLTQMQRKKTGNLSVRSLVDLVTVDDFVDSEYLETVLVAVPKIKEWLNSYERLTMVVPRSAKELLADDEFALYSVVIFKRDDFVQKCRERKFIVFSEEDMERERQELETTDLLQSARINFSESYVHIKVIRLFVESVLRYGLPSHYFAYLGPRS---DFDQEFFDFVMYEV Croqu1 FWIVAFRITTP-EFKTPPLSTLISLSEILAKHEPIANQTLLKILDTLQSLSLMMDDYEDYLLKWEWNRVKYNRVDSRKLEDLVESLTREVNAIDNSHKLKLATYNQAKAQLSAAQRKRTGNLSVRSLNDVVTRDHFVESEYLQTLIVAVSNIKEWMNSYESLTLVVPRSSNKISSDEEYTLFNVVILKKENFIQKCRERKFIVFDESEIEKSRQESKELELLRLSRINFSETFVHLKVIQTHIESLLRFGLPAHFQDSLESSVETDDLEKEVFEFVLFEI CryneH991 YWLISAPWEIP-ELKAGTLSSLLTLSDSLPKIDSAFTTTASKLLDQLRSLMARVNDAEEYLMAFKWDKGRW-GEG-GKVTEVVEALSREMAVIEATQKEKAQSYNLAKGGLTTLQRKQIGNLSQRSLLDIVKKGHLVDSEYLETLVVAVPKAKDWSNKYERLTMVVPRSSQQIASDDEYVLQTVTVFKKDDFIHKCRENKFIVWDDSALEKQRRQLAELGLLRLTRINFSEAYAHLKTVRLFVESVLRYGLPADYYAYLNNSSLGDDVEAEYYDIVLFEI Crypa2 YILLSLPFPIP-AFKIGTLDALVQQADELAKLHTNCEGVVQRVADSLKTILKMVNDTDQYLRTFSWNKVRY-RSD-RPMAELIETLQKELVNIDNDVKGKFNQYNSVKTNLAGLQRKQTGNLTTKSLTPIVDPSLLVDSEYLETHLIVVPARKEFLKSYETLAMVVPRSSIEVAKDEEFVLFAVTTFKKAEFLQKCRESKWTPYVEGGKEEEQKELERMEALRLGRTGWSEAVAHVMTLRVFVETVLRYGLPLEYYSYLGGNADDAALGNDYTAYVFYEF Debha1 YLALSLPFVLP-DFQIGTLDSLVQQSDELNKLDSQLSTSVAKVVDILNSVTKTVNGVLNYVESFQWNTSKY-RLD-KPLTQLVSLISNEAITLDNDVRSSYQTYQNAKSNFLAADRKKNGDLSIKSLHEIVRPEYFVDSEHLITVLIAVPKISDFEKSYETLTFVIPRSAKVIATDQEYSLYTVTLFKKQDFINQAREHKWHPYSEETLNNLRKEFDLSDLIRLATTAYSDIFVHIKAIRIYVESVLRYGLPPQFFGYLGGDGNNANLDTEYEPFVLYEM Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNEYEAADLIRLSKEAYMEMTVHIKLLRTFVESVLRYGLPPEFFEYLGGNAKDNSLDQDYEPFVLYHI Dicdi FWLISAPFNTP-ALRVGTLNSLITLNDELQKIDTIVESTTKKIARQLVDLVLSINGIPQYLQQFAWDDAKY-NLK-LSLQEIVEKISSAVSKIDDDLKIKSSEYSTLSSSVASEERKASGNLQVRTLNDLITADNIVQTDYFTTAFVVIPKEKEFLACYETISFVLGRSAKRVAQDNDYFLYSVILFKKENFKTKIIEKKWVVLEDNKPTQERSKLTE-SLIRWCRLNFPEAFVHLKVVRVFVESVLRFGIPFNFFKYLGSAHNETDDSEKFYPYISVSV Dmel YWIISAPFHIP-DLKVGTLDQLVGLSDDLGKLDTYVEQITRKVANYLGEVLLMANNLPQYLTRFQWDMAKY-PIK-QSLRNIADIISKQIGQIDGDLKTKSQAYNNLKGNLQNLEKKKTGSLLTRNLADLVKKEHFIDSEYLTTLLVIVPKANDWLTNYEKITMIVPRSSQLIQEDADYCLFNVTLFKKEEFKLHARERKFIVYNEEELAAGKNEMTKLPLVRWLKVNFSEAFIHVKALRVFVESVLRYGLPVNFYGHLDGASDNVDIQSEYFPYVFYKV Enthi YLLTTLPSMIPTQLKFESLDSLMTLSDDLVRIDSSVGTVVRRLCNTWVDVNIQFNDNETDLTQFRWDEKKY-PFT-ETAKVLTNRIYKDIQQIEVRLRDLVSKYQTTSRELAIENKKETGTLLTRRLDSCVPDDVIVDTEYLMTVFVVISKHKEFLKIYDTLNFVVCDSAIQVIVDNDFELYRVVIFRHDDFKNECRTYHYSVREVANIESAKSSLEESTLVRYCEANFVHVLFHMKILRLFTDSVLHYGLPTKYRPTIGTEV-REDLADSTFPFVFTSV Falba VRMVPLPYELP-SFKMGTLDMMMQVSDEIQKIDSFAESLVHKISSSLVQLSLTVGNLISYLSKFQWSDAKW-SSR-SNIRELLDLLSKFFTSTDTELKQRMVAYNNARSSLASLQRRTSGNFLVCDLAPYVNESHFPNSEYLATVLTVVPNEREWFKFIQRNDLTEPSLSVKVTSDNDHSVYTAVLPKKDLFKTKARAEKFIVYDPEQQAIERKELEALGLHLWLKTNFSEAFFHLKTLRAHTEAVMLHGPP---RARLCG------------------- Fomme1 TWLISAPFGIP-SFKTGTLDLLVTLSEDLPKQDTYFTSVVAKIVDTLRNLLTLVDEVESYILQWRWNEGRY-SAQ-KSAKEIADTLSKELSSIDNVMKAKLNNYNLAKGQLVQLQRKRTGNLSVRSLVDIVSKDDIIGSEFLETVFVAIPKVKDWKLKYERISMVVPRSANLIDSDDEYSLFGVVIFKRDEFSQKCRENKFIVYTDELAAKHQQELDLAELLRISRTNFSEAFVHLKVLRLFVESVLRYGLPASYFAYLAPRS---EFEQEFLDYVIFDV Fusgr1 YAFLSLPFNIP-DFKIGTLDALVQQADELTKLEASCEAVVSKVADSLKNVLKMVNDTDQYVSTFSWNKIRY-RAD-KSLAELISTLQKELANVDTDVKTKFNQYNSVKTNLAALQRRQTGNLSTKSLTPIVDPALLVDSEYIETHLIVVPGKKDFLKGYETLAMVVPRSAVEVAKDDEFVLYAVATFKKAEFLAKCREQKWTPYVEGGRQEEQRELDRVEALRMGRTGWSESVIHVMTLRVFVEAVLRYGLPLDYYSYLGGNADDAALGHEYTAYVYYEI Galma1 TWLVSVPLAIP-TFKTGTLDSLIALSEDLPKQEGFFTTTVAKTVETLRNLLILVDEVDSYLLNWKWKDGRY-DVQ-KSLRDLVDILNKEMVSIDSALKAKLNNYNLVKGSLTQMQRKKTGNLSVRSLADVVSKDDFIDSEFLETVLVAVPKTKEWNINYERLAMVVPRTSKLIDSDDEFSLYSVVMFRRDNFVQKCREQKFIVYSEEEIAKQKQDMEMAELLRLSRTNFSESFVHLKVIRLFVESVLRYGLPAEYFTYLSPKS---EFDQEFFDFILYEV Ganpr1 YWFISAPFNLP-EFKIKNLDTLVVLSDDLTKIDASCEGIVMKIAESLKQLLLSVNDVDQYLLSFQWNSMKY-RTD-KTLREITDTISQEVSNIDILMKQKLSAYQQIKTQLGVLQRKTTGNLAVRGLGDIVKKEHFVDSEYLSTVVVAVPKYKEWISTYETLAMVVPRSSQLIAEDDEFGLYTVTLFQREEFTQKARESKFTVWNDSQLQQEKKELAEVNLLRLSKTNFGEVFIHVKALRVYVESILRYGLPPDFYAALG---KEKEVDKEFFPYVSFAV Gloin1 YWFISVPFIIP-EFKIGTLDALVVISDELIKYDQSFESTAFKIVDILRTLLLIVNDVEQFLKTFQWDTMKF-RAE-KSLQEIAQILNKEVASIDNIMKNKSGHYNQIKGNLQALERKQTGNLAVRNVAEFAKKEYFIDSEYLETLVVAVPKYKDWNSKYETLAMIVPRSSQKIAEDNDYGLFTVTLFKRDEFANKCREEKFVVYDENDMENQRKEFEEVELLRLATANFGEVFIHLKALRVYVESVLRYGLPPDFYGKLD--------DKDYYPYVYFHL Hisca1 YILLSLPFAIP-EFKIGTLDTLVQQADELARLEALCHNVVGKVGDVLKNVLKTVNDFFWYLRTFQWNKVKY-RAE-RSLAELIDLLQKEAASIDNDVRAKFSQYTQGKTTLAALQRRQTGTLSTKSLASVVDPRVLVDSEYLETHLIAVPSTKEFLRTYETMSMVVPRSSTFVASDDESTLYAVTTFKKAEFIHKCREHRWIPYVEGNEEKERRDLDKAETLRLARTGWSEAVVHVLVLRVFVETVLRYGLPLDFYSYLAGNADDPL-G-EYTAFVYYEI Klula1 FILVSLPFPIP-DFKIGSLDTLVLQSEELAKIDSQIYSSLQKIVEILNALTISINKIPEFLTHFQWDSRKF-KLE-KSVKELIHDLSIESFQLDADVRSTYSNYNNAKSNFAAAERKKTGDLSVRSLHDIVKAEDFINSEYLTTVLVAVPKKQDFEKHYETLAKVVPGSATVLKQDDEFILYNVHLFKKHDFQNACRERKYIPYSEELIDQLKKEHDTAQLIRLAKTAFQDVFLHIKALRVYVESVLRYGLPPFFFSYLAGNANDTSLDTEYEPFVLYSI Lacbi2 TWLLAVPLDIP-SFKTGTLDSLVSLSEDLPKLDTYFTATVAKTVDTLRNLLTLVNETDSYLIDWKWNEGRY-GVQ-KSLRELVDLLNKEMNSIDNAMKSKLNNYNLVKGSLTQMQRKKTGNLSVRSLADFVSADNFIDSEYLETLLIAVPRVKDWNSKYERLAMVVPRTSTEIASDDEFVLFSVVIFRRDEFLQKCREQKFIVYSEDEIAKQRQELEMAELLRLSRTNFSESFVHLKVIRLFVESVLRYGLPSNYFAYLRPRS---EFDQEFFDFVLYEV Lenti61 TWLISVPLSIP-SFKTGTLDSLIALSEELPKHDSFFTATVAKTVDTLRNLLVLVNEVDFYLLRWSWNEGRY-GVQ-RSLREMVDVLSKEMTSIDNVMKTKLTNYNLAKGSLVQMQRKKTGNLSVRSLVDIVKKEHFVDSEYLQTVLVAVPKVKEWNVKYERLTMVVPRSSTLIDADDEYSLFAVVIFRRDDFVQKCRENKFIVFSEEAIEKQREELETAELLQVSRTNFSESFVHLKVLELFVESVLRYGLPAHYLAYLGGRS---DLEQEYFDFVLFEI Malgl1 NWIISVPLRIP-SLKTGTLESLIIMAEDLPKIDNLFAAIVSRIVDALRALLLNIDGVEDYVMSWQWNSGKY-RIE-KSLNELMELLTKEMQSIDHIMKQKLSSYSAAKGQLQQLERKKHGNLTVCSLADIVHKDDMVNSEFLVTLLVVVPKAKDWLSKYERLTMVVPRSSSELAQDDEYILYNVTLFKKDEFIQKVRENKFHLWDEGLLAREREELEEAELLRLSCINFAEAYFHFKVIRTFVESVLRFGLPASYFSYLNEY-QQHETEQEVFPFVLTEQ Mellp23 FWIVAFRITTP-DFKTAPLSTLINLSEILAKNEPIANQTLLKILDTLKSLNLIMEDYEDYLLKWEWNRVKYNRVESRKLEDLVESLTKEILAIDNSHKLKLNTYNQAKAQFSATQRQQAGNLSVRSLSDVVTREHFVDSEYLQTLIVAVPNVKEWMNSYESLTLVVPRSSTKITQDSEYTLFNVVVFKKDDFSHKCREKKFIVMDESEIEKSRSEARQLELLRLSRINFSETFVHLKVIQTHIESLLRYGLPAHFQDSLESNSENEEADKEVFEFVLFEI Mnele FWLISTPFNLP-TLKVGTLDALMSLSDDLAKLDQFTEMVMIKVYNYMANALTKANNLRSYCNSFVWDVAKF-PTK-VSIKDIHDIIAKNITKIEKDFKTKSTTYNNLRSNLAQHEKKETGSLVTRNLGPIVNEEDFVASEYLVTVCVVVPKYKEWEGSYWKLAFVVPESSKRILEEGDQALYTVTMFRKEAFKNNAREKKFVVYSKEKISQQQNEVTNMPLIRWLKGNFSEAFIHVKALRLFTESVLRYGLPATFYGNLDKSADMGDISGDYYPYVYFDV Monbr YVLISVP--------VGTLSELIALSDDLAKHDQFVMSVTVKLANILKDLAMQVDGLPEATEHFSWDMARY-NVK-QLPRELAQQIIQDTQDVEVKLKTKSQGFNKIKGNLQAIERKSNGSLLIKSLANVVKPEHVVDSEFLVTLLVVVPK--------------------LVAEDAEYGLYTVTVFRKEDFKQNAREKKFVVFDAEEIAKDE----HE--------------VKQQALRVFVESVLRFGLPPDFYAALD---DVVDIQGEYYPYVSFDV Morel2 YWFVSVPLPIP-EFKIGTLDTLVLLSEDLAKQDTAFESSANKLVDIIRSLLLSVNEIDNFLKTFQWNTMKY-RTD-KSLVELAELLNNEVASIDTLMKNKMANYSVVKGNLQGIQRREVGNLASRNIVPFVKKEHVVDSEYLETLVVAVPKYKDWSNKYESLTMVVPRSSNKIAEDEEYGLYTVTLFRREDFTNKCREERFIVYSEDAIEEQRRELEEMTILRLAKTNFGEVFTHLKSLRVFVESVLRYGLPPDFYGHLG---EDATGEKDYRPFVFFSL Mucci2 -------MNIP-DFKIGTLDALVLLSDDLVKYDTVFEQSVNKLADMLNTLLLLVNDIDQYISTFTWNAMKY-RTD-KSLQETTATLSQEVTAIDNVMKNKLNLYTQNKNALQTLQRKQTGNLSVRNLNGIVKKQHCVNSEFLTTLIVAVPKFKQWNNRYETLTMVVPRSSVKIAEDEEFGLFTVTVFKRDEFSHKAREERFIPYDEDALQTQQRELEEAELLRLTKTNFGETFLHLKALRVFVESVLRYGLPP--------------------------- Mydma FWLISAPLNLP-ELKVGTLDTLVGLSDDLGKLDVHVESITKKLASYFAEVLLQINGPATYLTKFNWDSAKY-PTK-QALRSISEIISKQITQIDSDLKTKASAYNAIKASLQNLERKSTGSLLVRNLSSVVEKEHFINSEYLQTLLVVVPKTAEWETVYEKITMIVPKSSMLLTSDSDYSLYTVTLFKKDEFKHHARERKFIVWDDAEIAASKEEITKMPLVRWLKVNFAEIFSHVK------------------YAHLDGQQETVDIHGEYYSYVYFQM Neucr2 YSLVSLPFSIP-SFKIGTLDALVQHADDLTKLNAICEAVVSKVADSLAGILKMVNDTDSYICSFQWNKVRY-RAE-KPLGELIENLQKDIQNIDNDVKAKFNQYNAVKTNLSALQRKQTGNLATKSLTPIVQPDVLIDSEYLETHLIVVPLRKDFLRSYETIAMVVPRSALQIAQDDEFILFAVTTFKKADFLHKCREHKWTPYVEGGKEEEQRELERMEALHMGRSGWSESVAHVLTLRVFVETVLRYGLPLEFYSYLGGNADDASLANEYTAYVYYEF Orpsp11 VFVISAPFRLP-DFKIGTLDSLVVLSDDLSKYDQAFEGITNKIADNLKSLVLIVDDVDNYLQSFQWNDMKY-RTD-KSLREICDIIVQDVNSIDSLMKSRMTKYNLVKSQLTSLQRKQNGNLSVKSLVDIVKKEHFVNSEYLITLIVAVPKIKEWYASYETLTMVVPRSSELIAQDDEYGLFNVTLFQKDDFKKACRERKFQVFDENKISQEQKDLAAITALRLCKANFGEIFMHIKALRVYVESILRYGLPPNFYAKLG---KSEPIDKDYYPYVSFNI Pench1 YLLLSLPFPIP-EFKIGTLDALVQQADELSKLEASCESVVAKVGDALKNILKVVNDVDQYLRTFQWNKVKY-RAD-KPLAELIDLLQKEATSIDNDIRFKYSQYNQVKNTLSTLQRKQTGNLSTKSLASVVDPKSIIDSEYIETHLVAVPAVKDFLKTYETVAMVVPRSAQLVASDSEFTLYAVAAFKKAEFVHKCREQKWIPYVEGGKEEERKEVERVETLRLGRTAWSEAVIHILVLRVFVETVLRYGLPLDFYSYLAGNADDPG-A-DYTPYVFYEF Phybl2 YTLVSVPLLIP-EFKIGTLDGLVLLSDDLVKFDAVFEQATNKIADILSILVLLVNDIDQYISSFQWNSMKY-RTD-KSLQETTTLLNQEVASIDNVMKTKMNTYTLNKNALLTLQRKQTGNLSVKSLNGIVKKQHCINSEYITTLIVAVPRYKLWNNSYETLAMVVPRSSVKIAEDDEFGLFTVTVFQREDFAQKAREERFIVYDEDALKQQQGELEESELVRLARTNFGEVFVHLKALRIFVESVLRYGLPPDFYGRLG---SEDILDNNYRPYVQFEL Picst3 YLVLSLPIKLP-DFQSGTLDSLVQESDELSKYDQQLSASVSKVIDILSTVTRVVNSATDFIQSFTWNTTKY-RLD-KPINQLVKILSNEALTLDNDVRTSYQNYQAAKSNFLAADRKKNGDLSIKSLHEIVRPEQFVDSEHLATVLIAVPKKSDFEDSYETLTFVIPRSAAVIATDLEYLLYTVTLFKKQEFTAAAREHKWHPYSEETLNNLRKEFDITDLIRLAKTAYSDIFFHIRAIRVYVESVLRYGLPPQFFGFLGGDGNTSNLDTEYEPFVLYEL Plicr1 TWIISVPIAIP-SFKTGTLDILIGLSEELPKQDLFFTATVAKTVDTLRNLLILINEVDDYLLKWRWNEGRY-GVQ-RGLREMVEALSKEMTSIDNAMKSKLNNYNLVKGSLTQMQRKKTGNLSTRSLADVVSKDDFVDSEYLETLLVAVPKTKEWNSKYERLTMVVPRSSKVITSDSEFTLFGVVIFRKDEFVQKSRENKFIVYAEELLAKQREELETAELLRLSRTNFSESFVHLKVVRLFVESVLRYGLPANYFAYLGPRS---EFEQEFFDFVLFEV Polpo FWLISAPFNTP-ALRVGTLNSLITLNDELAKIDTFVEMTAKRISKQLSDLVLSINGIQQYLSQFKWDDAKY-NPK-STLQEIVDKIYSTASKLDEDLKTKTSEYGALTTAVHAEEKKLMGNLQVKSLSSIVTPEQFIQTEYLTTAFVVVPTEKEFLSTYETFCYVLMRSAKKIQGDSEYTLYGVCVFKKENFKTQCLERKFIVTETETKTQDTSKLSE-SMIRWCRLHFPEAFIHLKALRVFVESVLRFGIPINFFKYLGSQHNEEETSERFFPYVFISI Pucgr2 FWMVSFRLVLP-EFKVPPLSTLINLSENLSKTESLTNQTLQKIVETLKLLALIMEDYETYLFKWEWNRGKYNRVENRTLEDLVEVLVKEVTLIDNSHKLKLASYNQAKAQASASLRKRTGNLSVKSLADVVTKENFVDSEFLETLLVAVPNVKEWNNSYERLTLVVPRSSTKIAQDEDYTLFNVTVFKKEEYSQKCREKKFIVYDESEIEKSRTQQKEYELLRLSRINFSETFVHLKVIQTYIESLLRYGLPAHYYNSLESNTDQDELEKEVFDFVLFEI Punst1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 YTFISVPYTIP-DFKIGTLDALVLLSDDLVKYDAAFEQSVNKLTDILTSLTLLVNDLEQFVSTFQWNTMKY-RTD-KSLQETTANLNQEVTAVDNIMKSKLNAYTQTKNALQTLQRKQTGNLSVRSLNGVVKKQHCVNSEFLTTLIIAVPKYKQWNNKYETLTMVVPRSSIKITEDEEFGLFTVTVFQRDEFCHKAREERFIPYDQDALQTQQRELEESELLRLAKTNFGEIFLHLKALRVFVESVLRYGLPPDFYGRLG----EEILDNNYRPYVQFEL Rhoto1 LWLVSGPVEFP-EFKTGTLSSLLTLSESLAKQDPSVTSALQKTVDTIRSLTLVLDDYISYILPWEWNRAKY-RTEGRSLPEIVDALMKEVTSIENAQKNKTQQYGVVKGQLATALRKKTGNLSMRSLADVVSASDFAKSEYLETILVAVPKIKEWENSYERLTMIVPRSATKLAQDDEFALFSVTLFRRDEFAQKAREKKFIVYDEEAIEKQRRELENLDLLRLSRINFSDLFVHLKVIRAYVESVLRYGLPAAYLVP-----DDSAAEGEYYEFVLFEI Rozal11 YWLVSVPFPIP-DFKVGTLDQLVTVTDELAKMDVQFESMTIKIIQNLKSILVSVNEPDQYIRSFQWNTMKY-RQD-KPIKDICEVMVQEMTQLDNLIRSKMTSYNQVKASFGTFERKQTGNLLVKNLSDIVKKEHFVESEYMDTLVVAVPKQKEWLENYETLTMVVPRSTQLIIEDEEHALYTVTLFKREEFTTKAREKKFIVYNAEDIQKEKNQIAEMNLLRLLKTNFGEAFIHVKALRIFVESVLRFGLPPVFMKNTP-A-EQEGLDKEYYTYAYFPI Sacce1 FILISLPFKIP-EFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNLPINNVPEYLENFQWQTRKF-KLD-KSIKDLITLISNESSQLDADVRATYANYNSAKTNLAAAERKKTGDLSVRSLHDIVKPEDFVNSEHLTTVLVAVPKKSDFEKSYETLSNVVPASASVIAEDAEYVLFNVHLFKKQEFTTAAREKKFIPYSEELIDQLKKEHDSAQLVRLAKTAYVDVFFHIKALRVYVESVLRYGLPPHFFGFLGGNAQDTSLDTEYEPFVMYII Salro FALVSVPLGIP-LSRVGTLDELVALCDELMKHDSYMETVANKIAHALGEMLLLADSIDAFVGQFDWDSRRY-NAK-QPIRDLAQTLTQQVTAVETDLKARMQAYSKVKGALQAVERKNQGSLLIRSLSDIVKPEHVVNSEFLTTLMVVVPKYNDWKSSYSTLTYVCPGSTQLIHEDSEYGLFSVTLFRRDDFRAAAREKKFTVFDEETVAQQEADTTHLRLMDWLQLSFDQCFMHLKALRLFVESVLRYGLPPKFYGHLD---EVADVQGEYFPYVSFSV Schco3 TWLIAVPLGIP-SFKTGTLDSLITLSEELPKQDASFTAVVAKTVDTLRNLLILVNEVDDYL-AWAWNEGRY-GTQ-RSLRETVDALNKEMTSIDNTMKAKLQNYNLVKGSLTQMQRKKTGNLSVRTLADVVHKEDFVDSEYLETVLVAVPKTKSWNQQYERLTMIVPRSSKALASDDEYTLFSVVIFRRDEFVQKCRENKFIVYSDEEIEKARQELDTAELLRLSRTNFSEAFVHLKVLRLFIESVLRYGLPANYLSYLHRKS---EFEQEFFDFVLFEV Schpo1 FWILSVPFDVP-PFKVESLDVLISQSEQLTKQDAQCASAISKISDIIKNTVFMVQDPLEYVSSFAWNSSRF-HMN-KTISEISDRITSEIISFENDIRTRQTSFQQASSAFQNMQKKQSGNLSQKSLANIVHEEDVVGSDYLTNVFIAVPLEKQFLNSYETLTLVIPRSAKKLDQDSEFVLYTVVVFKKDSFITKAREAKYTIFEQGLRETEQSEFDDASLLRYASIAFSESFIHLKCLCVYVESILRYGLPPDFYAYLAQNPSMADLDEEYLPFVLFTV Sorma YSLVSLPFSIP-SFKIGTLDALVQHADDLTKLNAACEAVVSKVADSLAGILKMVNDTDSYLCSFQWNKVRY-RAE-KPLGELIENLQKEIQNIDNDVKAKFNQYNTVKTNLAALQRKQTGNLATKSLTPIVQPDVLIDSEYLETHLIVVPSRKEFLRSYETIAMVVPRSALQIAQDDEFTLFAVTTFKKADFLHKLDS-----HVQGGKEEEQRELERMEALHMGRSGWSESVAHVLTLRVFVETVLRYGLPLEFYSYLGGNADDASLGNEYTAYVYYEF Sphar ---------------------------------------------MLHDLLMTADNVEEYVRRFQWDIRKY-SVK-NSTRDLVDDIVAKVTEVENELKAKQLHYTTVKNALNGIERGNQGTLLARNLVNVVNAEDVIGSEHLQSVIVCVPTSREWQESYEKLTMVVPKSGRKIIEEQDYELWSVTLFRREDFKNAAREKKFIVFDPHAKQNAAKTRKTMGLVRWGKTYFSECFMHIKAIRLFVESVLRYGLPANFYQHLENRSDDAPAVGDYYPYVYIGF Spipu1 YVFISAPFALP-EFKVGTLDSLVVLSDDLSKADTTVEGIATKIADNMRNLLLSVNEIDAFLRGYQWNSMKY-RTD-KSLRELTDMILQEVNQIDTLMKTKMTAYTTVKSALQGIQRKQTGNLAVRSLNDIVKKDQLIDSEYLTTLIVAVPKISDWINKYETITMVVPRSSQKIAEDDEYALFTVSLFQRDEFTNKAREFKFHVWDAQAMAAEKKQLAEMTLLRLCKTNFGEVYIHIKALRVFVESILRYGLPPKFFARLG---DDQQIDKDYSPVVLFYI Sporo1 ---------------TGTLSSLLTLSETLAKQDPTITTAVQKTVDTIRSLT-----------PWSWDKSKF-RTESRSLNDVVDGIMKEVQSIENSQRNKNQEYAVVKGQLTQALRKKTGNLSMRSLTDVVSASDFADSEFLETILVAVPKTKEWENSYERLTMVVPRSSIELAKDEEYVLFSVTVFRRDEFSQKAREKKFIVYDEEAIEKGKRELEDLDLLRLSRINFSELFVHLKVVRAYVESVLRYGLPAAYLVPEHARK-DSEAEGEYHEFVVFEI Stehi1 TWLIAAPLSIP-SFKTGTLDSLVSLSEELPKQDSAFTAVVAKIVDTLRNLLILVNEVDEYLLQWRWNEGRY-GVQ-RGLREMVDVLVKEINSIDNVMKAKLNSYNLAKGSLTQLQRKKTGNLSVRSLADIVRKEDFIDSEYMETLLVAVPKVKEWNAKYERLTMVVPRSAAAIDSDDEYTLYSVVIFRRDEFLQKCRENKFMVFSEDLLSKEREELDTAELLRLSRTNFSEAFVHLKIVRLFIESVLRYGLPSNYFTYLSPRF---DFEQEFFDFVLYEV Tapde11 FLLVSVPFPIP-EFKIGNLGALVQHAEELIKVDTQCEGYVLKIADVLRNILQVVNDITSYLKSYTWNVGKY-RTD-RSIGDLIEILNKEGSSLENDVRTKFNQYNAVKGQLQQYQRRATGNLSTKHLGEVVRKEHVLGSEYMETLFFAVPIIKEWEGKYESLTMVVPRSSTKISEDQDFALYNVVVFKKQEFVAKAREAKFTPYDKEEVQRAKKEYEEAETLRLGRAAFGDAFTHVKALRVFVESVLRYGLPPKFFAHLGGRQGQDGLEDEYSPYVVFAI Thetr PFLLCVPFRIP-SLRVGNLDALFALTDDLGRTDAYVESVARKIAKQGVDLALSVEGMRGYVAEFSWNEQRYTSVG-ESTVALVQKIKDDVGRVEEQMKIKFAEVAELKSELAQLVRKTTGSLLMRSLDSLEGVKEVYSTAFLTTVYVAVRNVSEFEAKYEFLVAVVPRSAQCVAKDSEYTLFSVYVLAKDDFKREAAASKFVVADDDAVGDLPDARNARKQRRLAQANFGETYVHLKAIRVHVEAVLRYGLPVSYLGHLGDGA-----GDSFYPYVSVDL Treme1 YWLISAPWEIP-ELKAGTLSSLLNLSDSLPKVDAQFTQSVSKILDNLRSLLARVNDAEEWLMPWRWDKGRW-GVG-GKVGDVVDALTKEMNTIESTQKQKAQSYALVKGSLNNIQRKRTGNLSQRSLLEVVKKEDLVNSEFLETLVVAVPKEKEWQNKYERLTMVVPRSSQRIATDDEFMLQTVTVFKKEEFTHKCRENKFIVWDDSALEKQKRELKELELLRLSRINFSEAYAHLKTVRLFVESVLRYGLPADYYTYLASASNTEDVEAEFYDFVLFEL Trire2 YALVSLPFNVP-EFKIGTLDLLVQQADDLAKLDSTCQAVVAKVADSLRTVLKMVNDTDHYLRNFSWNKMRY-RAD-KPIAELISTLQKELNTVDNDVKSKFNQYNSVKTNLAALQRRQTGNLATKSLTPIVKPSLLVDSEYLETHLIAVPTKKDFIKSYETLSMVVPRSCVEVDHDDEFTLFAVVTFKKAEFIHKCREQKWTPYVEGGLEEEQRELDRVEALRMGRTGWSESVIHVLTLRVFVEAVLRYGLPLDYYSYLGGNADDAALGHEYTAFVYYEA Umbra1 YHLVSVPFSIP-EFKIGTLDALVLLSDELVKYDITFEQSVNKIVDLMRTLLLKVNDVDAYVKSFQWNTMKY-RTD-KSLQETTELLHQDMVSADNVLKNKMNSYTQTKSALQALQRKETGNLSVKNLNGIVKKEHCVNSDYLTTLVVAVPKVKRWYSTYETLTMIVPRSSVKVAEDDEYALFTVTLFQREEFTHKAREERFIVYDENAMEKQKKEAEETIIIRLAKTNFSEVFVHLKALRIFVESVLRYGLPPDFYGHLG---RDEHLDSSYKPWVQFDL Ustma22 YWIISVPLSLP-PLKTGTLESLISLSEELPKLDAQHTQIVAKIIETLRALLVLVNELDDYMLSWAWNTRKY-RVD-RGLREIVDTLSKELNSIDSVMKHKLANYNAAKGQLQQLQRKKHGNLSQRSLADVVHKDDFVRSEYLETLLVAVPKVKDWQARYERLTMVVPRSSHKISADEEYALFNVTVFKKDEFVQKCRENKFVVWDDELVLRQRQQLQEAELLRLARTNFSEAYAHLKVVRTFVESVLRYGLPADYYAYLESYN---DAEEEQFPFVLTEQ Walse1 -YLISIPIDLP-EFKYGTLANCISLSEQLQKFDDQITSTTQKYLESSTNTL-TINEAKAYLNNFVWNNYKYKRLN---LDEIIQSILKNINKVDQDFKVAQQNYQIAKGTLNQLQRKQMGNLSTKSLAQIVSEENVTNSDFLETIFVAIPIIKEWFNNYERLSMVVPRSSFEITKDSEFVLVNVSVFRKHDFIQACRENKYIVFDSSLAQKSSQELQQANFSHTLSNSFSEAYAHIKFLRLFVESVLRYGLPTDYYAHLSPSLNDISIDQDVYPFPLFTL Zygro1 FILLSLPFQIP-EFKIGSLDSLIVQSEELAKADNQIGSSIGKIVEILTSLNVPINNVPEYLENFQWMTRKF-RLD-KSIEELMKLITDESTQLDSDVRATSTNYNNAKTNLATAERKKTGDLSIRSLHDIVKPEHFINSEYLTTVLIAVPKKSNFEKTYETLANVVPGSAGIISQDSEYILYNVHLFKKQDFNAAAREKKFTPYSEELIDQLKQEHDSAQLVRLAKAAYADSFFHTKALRVFVESVLRYGLPPDFFGYLSGNAEDASLDTEYEPFVIYTI [Cluster1787.fasta_al_trimmed; alignment length = 255] Allma1 FELANVACRVALQFPDELLFVSDAVDFVILADTQYSACCVDEVAAQHIANVLVHFGRSCLS-QASHMPVLFAFGNDVDHVSQSLALVIYDVMYVVVIGVSHYSLHYD-PLSSLLMKRYALMTKARDADIIGIVVGTLGVANYVDMIANLKKLIKHGKKYYTFVLGKLNVA-KLANF-SEIDIFVLVACPESSLIDSKE-FYRPVVTPFELTMALW-TGEYGFTDVPYFSLVTGTFRQ-WRGLVVEGR-FGTAAGY Ashgo11 YAIESLARSITLQFPDDLLFDSALVKIWILADTAYSPCCVDEVAAEHVADVVVHFGDTCLN-PVETLPVVYIFGEDRAKVISLFVCLMANAPYLFHIGLLFLSTAYD-TQKPAMMRRYRFMHVARTASTIGILVNTLSLKSTRSLISSLVELIRCGKKHYMFVVGKPNVA-KLANF-EPVDVWCVLGCGHGGIVLANE-FYKPIVTPYELTLALW-TGAWDFNTVPEFDAVTGKYRQ-WTGLVEEGL-SGVARGY Aspfu1 YDIERTLKRIALQFPDDMLPDAPRVKLYILADTSYGTCCVDEVAAEHVADVVVHYGRSCLS-PTARLPVIYVFTHPIEPVIQAFIILAADVTYLFHISLLTLASPTT-DAPAALGRRYAILTRLSTVPIFGILINTLSVKNYLHIVEHVKQKIAAGKKSYMFVVGKLNAA-KVANF-SEIGGWVVIGCWESSLVDSKD-FWKPVITPFELELALW-TGAWDFQSIPEFDLRTGRYRT-WKGLVVEGR-KGIARGY Aurde31 YELDDVAKTIALQFPDELLHDAVPVQAYVLADTSYGSCCVDEVAAQHVAEVVVHFGHACLS-RTSRLPVLYVFGRDAEHAIATLVKLLYDVAYVFYVGLSTVLMSYD-PMTGRLARRYALVHRARAADVFGIVVGTLGVAAYLPLIGHLRAALAARKKTYTLAVGKLNPA-KLANF-PDIGAFVLVACAQTSLVDSRD-YFAPVVTPFELLLALW-TGDYDFARLPQYDFTSGRLRA-FKGLLEQGR-SGIARGY Batde5 FEVQSTA--VAFQFPDSLLSYSSAVDLVVLADTTFGSCCVDTVAAEHAVDLIVHYGPSCLSRPASTFPVLVVLEKDIPATVAYFVLVMYDLAYMFYIGLTNLMMAYN-PVLKLLMRRYFMVQKAKDADVIGIVVGTLGLASYLPVIENLKRLVLSGKKPYMLALGKPSPA-KLGNF-LEIDVFVLVACPQNALLETRD-FLRPVVTPYELCIALWDVSKYDLVTVPHFSLVTGAYRT-FQGLVQDGR-RGIARGY Botbo1 YGLPQAAKRVALQFPDELLPVSVPIQVFILADTSYGSCCVDEVAAQHVADVVVHFGHACLT-PTSRLPVIYAFSKDILHCVHSLVLVKYDVMYIFYIGLSNLLISYN-PLDKALMRRYATVQKARDADVFGILVGTLGIASYLPLISRLREILAGRKKSYTISVGKLNPA-KLANF-VEIECFVLVACPENSLIDNKE-FMQPIVTPYELELALW-TGRLDFKQIPAFSLMTGKYRT-FQGLLEQGR-SGIARGY Botci1 YEISRTVKKIALQFSDGMLSDAPRVKLYILADTSYGSCCVDEIAAEHVAQVVIHYGRACLS-PTARLPVIYVFTSNLESVIQAFIVIMADITYLFHISLLTLSSSTD-STTRALMRRYALLTSQSSSSVFGILINTLSVTNYLPTVNSLASLIRKGKKSYTFVVGKVNAA-KLANF-SEIDGWVVVGCWESSLVEGEA-LFKPVITPFELALALW-GGDWDFNALPEFDFRTGRYRT-WTGLVEEGR-SGVARGY Caeel FEIDATSQRIALQFPDSLLPYSEKVKTFVLADTSYRSCCVDEVAAAHACTALVHFGEACHSAPTDKIDVKYVLGSFIDQFRMEFIVLLMDSCFNIYLGFPN---HFN-PINRLLRKRLFLVEKLKDADTVGLVVGSVGVDKHREAVKRMREMCKAGKKIYVISVGKINVP-KLSNFSTDIDVFVLLSCPFGVVLDSSD-YFRPVVSYFEAEIALW-AADFEFAAFGDFSLISGKVRT-WKGLMGEGR-SGIAQGY Canalb1 YSLSELIKRITLQFPDNLICDSATIRVWILADTSYSACCVDEVAAEHVSDLVVHFGDACLN-EIDKLQAVFVLGKDVDAIVKQIVVLMSDAPHLFHITLLQLTTTYD-PISPNLMRRYKYVHQARMAGTVGILVNTLSLANTKVLLNTIKEKIKAGKKHYIFVVGKPNVA-KLANF-ESVDIWCILGCDHQGIIIINE-YYKPIVTPYELLLGLW-TGKWDYKSVPVFDPVTGRYRH-WTGLVEDGR-KGIARGY Cangl YSIDKLIVQITLQFPDTLVKDSSFIKFWALADTAYSACCVDEVAAEHVGDLVIHFGDACLN-AIQKLPVVYDFGKDTDVLLACFICLMSNASYLFHITLLYLTTTYD-VADPSLTRRYKNMHKARTAGCIGILVNTLSIRGTRETVNKLIKLIRNGKKHYLFVVGKPNVP-KLANF-EPVDIWCILGCGQSGIIVFGE-FYKPIITPYELTLALW-TGKWDFQKAPEFDAVTGKYRA-WTGLVEEGI-SGIARGY Capow YEIERCVGRIALQFPDTLMVDAPAVHVFVLGDTSYGSCCVDEVAAQHVADLVIHYGRTCLS-PPSHLPVIFVFGKNVADCRDKFVIVAFDVTCIFYVGLTNLMMSYD-PVSRALMRRYFLIQKAKEAQTVGIIAGTLGVADYMTVIERLKRLCKAGKKTYVFVMGKLNVA-KLANF-MEIDVFVLVACPENSLIDSQD-FFKPVVTPFELELACW-TGAYDFRQIPEFSFISQSMRS-FRGLAVEGR-RGIASGY Catan2 ---------------------------------------------MHFANCVVHFGRSCLS-GVSHMPVLYAFGKDVDHAIASLAAVKCD-RYLVVIAVAHYSLHYN-PLDSTLMKRYALMQKARDASVIGIVVGTLGVANYLSTIASIKRLIRHHKKYYTFVLGKLNVP-KLANF-MDIDVFVLVACPESSLIDSRE-FYKPVVTPFELGMALW-TGEYAFGEVPYFSLVTGTYRE-WKGLVVEGR-FGNAAGY Cioin YDVNQCVTKVALQFPDEMLNDAVAVNIYLLADTSYGNYDVDEVAAQHVADLIIHFGKASLT-STSKTKTLFVLGKSIEEVVASFVFIFAESTYLFFIGLKMFLFVFD-PDTRQLAKKYYLVEKLKDAKTIGIVVGTLGMAGYLEIIEHLKHIISTKRKSYTFVVGKINPA-KLANF-SEIDVFVVVACPEQTNLDSSE-YFKPLVTPYEVEVAYW-GEPYNFRDL-----------T-WKGLAEDGR-SGLPVHY CocheC53 YEIERTVKRIALQFPDHMLGDAPRVKLFILGDTSYGACCVDEVAAEHVADVVVHYGRSCLS-PPSRLPVIYVFTEDIDATIATFVVLMADIPYLFHISLLALSSPTT-EPAKTLNRRYALITSLSTTPIFGILINTLSVKNYMHILSHVQQQIAAGKKSYTFVVGKVNAA-KVANF-SEVGGWVVIGCWESSLIESRD-FWRPMITPWELGVALW-TGAWDFQKVPEFDLRTGQYRT-WQGLMEEGR-SGIARGY Coere1 YEIDRTACRIALQFPDELLPDSTLVQVFILADTSYGSCCVDEVAADHYADIIIHYGRTCLS-LSSRTPVYYVFGRDPKDCAQKTILLMCDVPYILYVGLTNIMVSYD-PRRRHLNRRYYMVQKAKDANIVGIVVGTLAALRYLRVVEALKQMLRAGKKYYVFVVGKLNVA-KLANF-AEIETFILVACPENSLVDSKD-FYQPVVTPYEMLLAIW-TGDYDFHTFPHFSLITGTLRS-FRGLAVEGL-SGIARGY Conco1 FEIEKTCEQIALQFPDELLPISNYIPNFILADTSYGSCCVDEVAVSHVSGVIIHYGHSCLT-RVDKYPVIYVYGKNLDDCIEKSIIVTGELDYVIYIGLSQLIIAYN-PST------------AKDSSVFGILVGTLGVGSFLPMIDHLKQLIKKGQKYYTFVMGKLNVA-KLANF-MEIDVFILVACPENSLIDSKD-FYKPVITPYELQLALW-SGKLDFETIPHFSLITGKFRE-YIGLAEEGR-RGVARGY Conpu1 YEIERTASQIALQFPDELLHDSVPIDLYVLADTSYGSCCVDEVAAQHVADLMVHYGHACMS-QTYRLPVIYVFGKDVDQCVNKFVALRYDVAYILYIGLTNLLMSYD-PSSRLLMRRFAAVQKARDADVFGILVGTLGVASYLPLIAHLRAQLAARKKSYTISVGKLNPA-KLANF-MEVECFVLVACPENSVVESKE-FFKPIVTPFELEVALW-TGRYDFEQLPSFSLVTGKYRT-YQGLLEQGR-SGIARGY Copci FEIERTRRRVALQFPDELLGYSVPVEVYILADTSYGNCCVDEVAASHVADFIVHYGYACLS-KTARLPVLYVFGKDVEDCK-----------RIVYVGLTNLLLSYD-PTSRLLMRRYYTLLKARDASTFGILVGTLGVSQYLPLISHLRSLLRNGRKSYTISVGKLNPS-KLANF-LEVECFVLVACPENSVVDAKE-FLRPIITPFELEVALW-DGTYDFASIPHFSLVSGKLRT-YTGLLEQGR-SGIARGY Croqu1 YQIMETAHIIGLQFPDFLLPISVRIELYLMADTTYGSCCVDCLAAQHVAEAIVHYGPACLT-TIAHLAVYYVLPR---ELYSSFLLLMYDVGYIFYIGLTHVILALD-PSSKLLMKRYATIQRARDADVFGILVGTLGVQHDLRLIHRTKNLIEFKKKSYVVSVGKLKPE-KLINF-FEIECWVLIACPEHSLLDSKQ-YNVPVITPWELDFALW-DGQYDFDRLPVFSMITGQYRT-YNGLMEKGR-FGIAQTY CryneH991 FEVSETVKTIGLQFPDELLPSSVSVQAYVLADSTYGNCCPDVLSCLHLADFLVHYGHACLT-PTDALPVHYVFPRDVKQAMGSLIVVVWDVSYLWYIGCMNLQMVYS-PSSRLLSRRLFALHQALSADVFGLIVSNIGLASSKPLLAQLREDLKAKKKSYTLSVGRLNPA-KLANF-AEIECFVLVGCAEGGVVDSKD-FLRPIITPWELELALWAPENWDLGTVLEFSLITGTMRE-FQGLLEQGR-SGVARGY Crypa2 YEVERTAKRIALQFPDHMLGDAPKVRIWILADTSYSACCVDEIAAEHVADVVVHYGRSCLS-PTSRLPVIYVFTRDMDAAVQSFVVLMADVAYVFHVSLLALSSATADSESGLLGRRYAKLLNLTSAGIIGILVNTLSVANYLSSIESIRKQIAAGKKSYTVVVGKLNPA-KLANF-SEIEGWVIVGCWESSLVEEDAGFFQPVLTPFELEVALW-GLSWGIESVPVFDLRTGKLRT-WQGLIEEGR-GGIAKGY Debha1 YNISEICKHVTLQFPDSLICDSASIKLWILADTSYSSCCIDEVAAGHVSDLVIHFGDACLN-VVESLPAAYVFGKKLDSVITQFILIMADAPHLFHIELLQLTTTFE-PKSPKLMRRYRYMHMARSAGTVGLLVNTLSLANTKTLINKIGQKIKAGKKHYVFVVGKPNVA-KLANF-ENIDIWCVLGCDHQGIIINNE-YYKPIVTPYELLLALW-SGKWDFNKVPEFNPVTGQYRH-WTGLVEDGR-AGIARGY Dekbr2 YSVDKTAKEVALQFPDDLVRDSAIVRVWVLADTSYSPCCIDEVAGEHVADLILHFGEACLN-PVEKVNSAYIFGKDTAKVIELFICIMTDTQYLFYIGLILLSTVVD-PVTPSLSRRYRFMMIARNASTIGILVNTLSLENTRKLLNKVVKWIKAGKKHYMFVVGKPNVA-KLANF-DTIDVWCILGCGQSGIVIYGD-YYKPIITPYELQLALW-TGKWDFKEVPEFDPVTGKLHT-WTGLVEEGR-SGIARDY Dicdi FQVSESIKKIALQLPDYLLWASSELKVFILGDTSYGSCCVDEVTSSHLSDFIIHYGHSCLS-PSSKIPVQYVFGKELNKLVES-FVIFYDLLYFIWIGLTNLLMRYY-IDDKSLMRRYHISEKCKDASIIGIVVSTLSVQKYSETIDGLKKLIISGKKPYVFVVGRLNVP-KLANF-SEIDIYVIVACHENTMVDSKD-FYKPIATPFELNLSLW-TGEYDFGRVHHFSLVTGRIKT-YKGLAIEGM-SGIPKNY Dmel -----SVKRVCLQFPDDYLPHSNAIKVFILADTTYGSCCVDEIAAAHVADSVIHFGNACRSRAA-RLPVLYLYPEDVNVLLSKLVCVYLDIGYCIFIGFANLSLSKN-PL-QFIRRRYFHIEKCKDAQTLGLIVATLSAEGYLDVVTRLQTMAKRGIKTQLISVGRINPA-KLANF-LEIDCFVLIGCPFNNMYDSKE-YYKPIVSVFEAEMALW-HMRYDFKQLNDVSLVSGRLRT-WQGLLQQGL-SGIPINY Enthi -------RELSAQIHMTLLP-----NTIAILHTPYQSC------SEHSKTLVVEVGGICEQ-----RNNVYIYPLDNATII---YSFMKSLNKIIYGS------YFN-PMNKYVMNRYSLFDKIRSATTFMLLLLDPD-----ESFKKLRSLLM---EYRVITVFMGNPENKLLNYSGQVDIAIVLGSDLSELKFEGD---IPTVTPYEVLYSLW-NGEY-----P---------RS-----IN----------- Falba YDIASTISRICLQFPDSLLHHSVIVSFFLMADSSFAEVEVDEIAAAHVADAVVHYGRAALG-ATTRIPVQFVFGKPIDEVAPLALAVFYDVGYALFIGLAQLMLTVD-PAQRVLSRRLHLIQRARDALVIVLVLASPSSPYALPICRRLQRLAGQGRKTYTLVMGQIRPE-KLANF-LEAEVFVIIGGAETITEDDRD-YFRPVITPFELEIALW-TGNYDPADVVYYSLITGRMRH-YQGLATEGR-RGIAKGY Fomme1 YEIENTVKR----FPDELLHDSVPIEAYVLADTSYGSCCVDEVAASHVADVLVHYGHACLS-QTSRLPIIYVFGQNVEDCVDKILHLRHDVGFMVWVGLTKILMSYN-PQSKLLMRRYAILQKARDADVFGILVGTLGVASYLPLMKYLRERLKAHKKSYTVSVGKINPA-KLANF-MEIECWVWVACSE-GIVDSKD-YLRPIITPYELELALW-TGKYDFEELPMFSLVSGTYRS-YQGLLEQGR-SGIARGY Fusgr1 YEIVRTAKRIGLQFPDFMLVDAPRVRIYVLADSSYSACCVDEIAAEHVADVVVHYGRTCLS-PTSHLPAIYVYTTDYEVTINEILVIMADLTYIIHISLLALYTSTP-SPAGLLRRRFAKVLALASAGVIGILVNTLSVANYLSSINTLRERIAADKKSYTIVVGKLNPA-KLANF-AEIEGWVVVGCWESGLIEDDAGYWRPVITPFELEVALW-GGEWGIEKLPEFDMRTGKLRT-WQGLVEEGR-SGVARGY Galma1 YEIERTVQRIALQFPDELLHVSVPIELYILADTSYGSCCVDEVAAQHVADLVVHYGHACMT-QTSRLPVVYIFGRNVEKCATGFVLLRHDVAFIFYVGLTNLLMSYD-PSTKLLMRRYVAVQKARDADVFGILVGTLGVASYLPLISYIRRLLRKQKKSYTISVGKLNPA-KLANF-LEIECFVLVACPENSLIEDKE-FLRPIVTPYELEVAMW-TGQYDFEKLPVFSLVTGTYRT-YQGLLEQGR-AGIARGY Ganpr1 FELSRTVSKIALQFPDELLAHAPRLSCFILADSTYGSCCVDEVAAKHVSDLIVHYGHSCLS-LPSATPTLFVFGKDLEKCADAFIALVADVSYVFYIGLTHLIMSYAPPLGRLLARRYRAVQRARDADVFGVVIGAAGLAHSLPLLRSLLRLFRARRKHYVLSLGRPTPT-KLANLHHDVDCFVLAACGENSLAVEKE-VGRAVVTPVEVALAL--GGEYGFEGVPHFSLVTGGLRT-FRGLVQEGR-SGVASGY Gloin1 YEIDRTVEKVALQFPDELLADSTEVKIFVLADTSYGSCCVDEVAAKHVAECIIHYGRSCLS-PCSQLPVLYVFGKDLAHCLESFLLIMYDVVYIFYIGLTNIIMSYN-PEIRALMKRYYMIQKAKDADVIGIVVGTLGIASYLIVISHLKKLIIAGKKPYTFVMGKLNVA-KMANF-MEIECFVLVACPENSLIDSKE-FYRPIVTPFELEIALW-TGEYDFQLLPHFSLVTGKY------I------------- Hisca1 YDIDRTLKRVALQFPDDMLPDAPRVRLYILADTSYGTCCVDEVAAEHIADVVVHYGRACLS-PTTRLPVIYVFTHDTALVIEGFVIIAADVTFLFHISLLTLSSPTD-EESISLRRRYAILTSLSTVPVFGILINTLSVKNYLHVVEHVKAQIAAGKKSYTFVVGKLNAA-KVANF-SEIGGWVVIGCWESALVDSSD-FWKPVITPFELELALW-TGEWNYQTVPEFDLRTGRYRT-WQGLVVEGR-NGIARGY Klula1 YSVPELIKKITLQFPDELVLDSSIVKVWILADTSYSSCCVDEVASEHVGDIVVHFGDACMN-AVQKLPVVYSLGRDLDLVVSQFICLMADAPHLFHVTLLYLTTLYD-PSSPSMMKRYKFMHMARTAGTIGILVNTLSLRNTKETMNKLTKLLKNGKKHYLFVVGKPNVA-KLANF-EPIDIWCILGCGQGGIVLYNE-FYKPIITPYELLMALW-TGQWDFKSIPEFNAVTGKYRH-WTGLVEEGT-AGVARSY Lacbi2 YEITRTAKRIALQFPDELLHDSVPIDLYVLADTSYGSCCVDEVAAQHVADAMVHYGHACLS-QTSRLPVIYIFGRDVDLCVERLVLLRYDVSYVFYIGLTNLLMSYN-PTSRLLMRRYAVVQKARDADIFGILVGTLGVASYLPLIKHLRTLLAHQKKSYTISVGKLNPA-KLANF-MEIGCFVLVACPENSLVEAKD-FLRPIVTPYELEVALW-TGRYDFEKLPVFSLITGSYRS-YQGLLEQGR-SGIARGY Lenti61 YDIARTVTRIALQFPDELLPHSVPIELYILADTSYGSCCVDEVAAQHVADALVHYGHACMS-QTSRLPVIYVLGKDPSHCAECFVLLRYDVGYILYIGLTNLLLSYD-PKTKLLMRRYAVVQRARDADVIGILVGTLGVANYLPLISHLRDIIKAHKKSYTLSVGKINPA-KLGNF-LEIECFVLVACPENSLLDAKE-FLRPIVTPYELELALW-TGRYDFEQLPVFSVVTGKYRT-FRGLLEQGR-SGIARGY Malgl1 YDIESTAQRVALQFPDEALIDSVPVRLYILADTSYGSCCVDQVAASHVADALVHYGHTCLS-ATASLPSLYVFPKAIDDVVDGLVVLTYDVAYALYVGLTHLLLSYD-PKTRLLMRRYAAIQKARDASVVGLVIGTLGIHAYLPLLNELRRILTSRRKVYTISVGKLNPT-KLANF-LEIDVFVLVACPENSLLDTRE-FLRPVVTPWEMMLAVW-SGAYDLERVPHYSFATGTYRT-WHGLLEEGM-AGFAQRY Mellp23 YEINETVHIIGLQFPDHLLPISVRIEIYLMADTTYGSCCVDCLAAQHVAQAIVHYGPACLT-TIANLAVYYVLPR---ELYSGFLVLMYDVGYILYLGLTHIMLALD-PSSKLLMKRYATIQRARDADVFGILIGTLGLKHDLELIHRTKSLIEFKKKSYIISVGKLKPE-KLINF-IEIECWVLIACPEHSLLDSKQ-FNVPVITPWELDLALW-DGHYDFDGLPVYSMITGTYRT-YNGLMEKGR-FGIAQGY Mnele FELESCRHNVALQFPDHLLAYSPTVHFHILADTNYGACCVDEVAAQRLTQAIIHFGHSCNS-KVLSLPTLFIFGKDLDNLVQSFVLVVFDSVYIFYVGLTNCILSYD-PSSKMLIKRFSNIEKIKRCKIIGILIGTLGIKNFREVIDRMKRVIKADKKFYIVSIGKPNPP-KLANF-AEIGAFVMVGCPENSLLDCTE-FYQPIVTPYELEIACW-EIDYDCSSLP---------RT-WTGLLKQGQ-FGIAGFY Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 YEIERTVKRIALQFPDDLLPDSGLVAVFILADTSYGSCCVDEVAAQHIADAIIHYGRSCQS-PTSRLPVIYVFGKDVQDCATVFVILMYDVIYIFYIGLSNIMMSYN-PEKKALMRRYFLVQKAKDADVIGIAVGTLGVASYMTMIQHLKALIEKGKKAYTFVMGKLNVA-KMANF-MEIDCFVYVACPENTLIDSKE-FYRPIVTPYELEIALW-TGDYNFQELPHFSLVTGQFRQ-FKGLATEGR-AGIARGY Mucci2 YEIDRTVKRIALQFPDEYLADAANVDIFVLADTSYGSCCVDEVAAEHVADLIVHYGRSCLS-PTSRSPVLYVFGQDMEHCKQEFVIIMCDVEYIFFVGLTNIMMTYN-PKTKMLMKRYFLVQKAKDADTIGIVVGTLGVASYLNIIDHLKKVIKAGRKSYFFVMGKLNVA-KMANF-MEVDCYVLVSCPENSLIDSKE-FYRPIVTPFELEIALW-TGNYDFSKLPHFSLITGQYRT-YRGLVQEGL-SGIARGY Mydma FEIYESVKRVALQFPDELLKYAKFIKFYVLADTSYGNCCVDEVAASHIADAIIHYGHSCLS-VTEKTPTFYVFGRNLDDFSLCTVLLLYDVKYILFIGLRNLMMVYN-PSLKSLMKRFYLIQKAKDAQIVGIVMGTLGIEKYKEIVQRLKKVLKAGKKYYTFIMGKLNVA-KMANF-MEIDIFVLVACPENSLIDSKE-YFKPIITPFELEIACW-NGEYDFCELPEYSLITGQLRT-WQGLAVDGR-AGIASDY Neucr2 YEITRTARRIGLQFPDHMLCDAPRVRVYVLADTSYSACCVDEIAAEHVADVVVHYGRSCLS-PTSRLPVIYVFTKDRDAALVKFVVLMADVTYIFHISLLALCSQTS-SDS-LLGRRYARLLSLTTAGIIGILVNTLSVSNYLSSIDSIRKQIAAGKKSYTMVVGKLNPA-KLANF-AEIDGWVVVGCWESSLIEDDAGFYKPVITPFELELALW-TGEWGIEAVPEFDWRTGKLRT-WVGLIEEGR-GGVARGY Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YDIERTLKRIALQFPDDMLPDAPRVRLTILADTSYGTCCVDEVAAEHVADVVVHYGRSCLS-PTARLPVIYVFTHPLEPVVRAFVIIAADVTYLFHISMMTLASPTN-DLSAVLRRRYGTLASLTTVPIWGILINTLSVKNYLHIVDHVKERIAAGKKSYMFVVGKLNAA-KVANF-SEIGGWVVIGCWESSLVDSKD-FWKPVITPFELELALW-TGAWDFQAVPEFDFRTGRYRT-WKGLVKEGR-KGIARGY Phybl2 YEIDRTVKRIALQFPDELLADATAVSFFILADTSYGSCCVDEVAAEHCADLIVHYGRSCLS-PTSHLPVLYVFGQDIDHCIKEFVIVMCDVEYIFFVGLTNILMTYD-PKTRMLMKRYVLVQKAKDANTIGIVVGTLGVASYMNIIEHIKKLVSSGRKSYLFVMGKLNVA-KMANF-MEVDCYVLVACPENSLIDSKE-FYRPIVTPFELEIALW-TGDYDFSKLEHFSLITGQYRS-YRGLVQEGR-SGIARGY Picst3 YCLDELVNRITLQFPDLLICDSATIKLWILADTSYSPCCIDEVAAEHVSDLVVHFGDACLN-PIDKLPAVYVFGKDVANLVNQFILLMSDSPHLFHISLLQLVTLYD-AFTPNLMRRYRYMHMARSAGTVGLLVNTLSLANTKKLINTMAKRIKAGKKHYIFVVGKPNVA-KLANF-ENVDMWCVLGCDHQGIIVSNE-YFKPIVTPYELLLALW-TGKWDFKQVPEFDAVTGRYRH-WTGLLEEGR-GGIARGY Plicr1 YEINRTAKRIALQFPDELLHDSVPIELYVLADTSYGSCCVDEVAAQHVADALVHYGHACMS-QTSRLP-------NVDACVSSLVLLRHDVAYILYVGLTNLLMSFD-PCTRLLMRRYAVVQKSRDADVFGILVGTLGVASYLPLITHIRRLLAARKKSYTITVGKLNPA-KLANF-MEIECFVLVACPENSIIDTKD-FLRPIITPYELEIALW-TGRYDFERLPVFSMVTGKYRT-YQGLLEQGR-SGIAKGY Polpo FEIDTSAKRVALQLPDSLLWAARTIKVFILGDTSYGSCCVDEVTASHLADFIIHYGHSCLS-PATKLPVQYVFGKDSDGFINSYTIVFYSLEYILWIGLTNLLMRYN-PENQSLMKRYYISNKCKEANIIGIVVATLTVQKYSETIDSLKKLIINGKKPYVFVVGRLNVP-KLANF-SEIDIFVIVACPENTIVDSKE-YYKPIATPFELNLALW-SGEYDFGKLYHFSLTTGKIRT-YRGLAVVGK-TGIPKSY Pucgr2 YKILETVTIVGLQFPDELLSISVPIELYIMADTTYGSCCVDHVAAQHVAQAVVHYGQACLS-ITPSLPVFYVLPKMVESLYS-MILLMYDVGYVFYVGLTHFLVAVD-PNQKLLMRRYATIQRARDADVFGILVGTLGVRHYLEMINRTKKLIEFKKKAYIISVGKLKPE-KLMNF-AEIEAWVLVDCPESSLLTPKQ-FGAPIITPWELEIALW-DGKLDFEQIPVFSMVTGGYRT-YFGLVSAGR-YGIPQAY Punst1 YDTQRVAKRIALQFPDELLPISVSIDLFVLADTSYGSCCVDEVAAQHVADVVVHYGHACMS-KTSRLPVIYVFGKDVVGCASHLVLLKHDVRYVLYVGLTNLLLSYN-PDSKLLMRRYAVLQRARDADVFGILVGTLGVASYLPLITHLRSVLKAQKKSYTISVGKLNPA-KLGNF-AEIECFVLVACPENSLVDAKE-FQRPIVTPYELEIALW-TGRYDFEALPIFSLVTGKYRT-FKGLLEQGR-SGIARGY Rhior3 YEIDRTVKKIALQFPDEFLADAAAVEIFILADTSYGSCCVDEVAAEHVADLIVHYGRSCLS-PTSRLPVLYVFGQDMNHCIGEFVVIMCDVEYIFFVGLTNIMMTYN-PKTKMLMKRYFLVQKAKDAETIGIVVGTLGVG----------KVIRSGRKSYLFVMGKLNVA-KMANF-MEIDCYVLVSCPENSLIDSKE-FYRPIITPFELEIALW-TGNYDFSKLPHFSLITGQYRT-YRGLVQEGL-SGIARGY Rhoto1 YEVDLTLQRIALQFADEQLHDAVAVELYVLADTTYGSCCVDEVAAQHVADFVVHYGHTCLS-PTARLPVLYVLTKDPDHAASSLAIVLYDVGYLFWIGLSNVLLSYD-PTTRMLMRRYATVEKAKDADVIGILVGTLGVAAYLPLITHLRQLIAHHKKSYTVAVGKLNPA-KLANF-IEVECFVLVACPENSMIDSKD-FLRPIVTPFELELALW-TGDYDFAQLPVFSAVTGTYRT-YKGLLEMGREGGIARGY Rozal11 YFLEPCLRTIALQFPDDKLEDASEIQVYVLADTSYGNCCVDEVAASHVADLIIHFGYSCLSKPAK--------SKNLKECVSALYLIIFDPCFILYVGQLSIMSILE----SMLRKRFHL--------------------------------------------------------------------------------------------------------------------------------------- Sacce1 YNVEPLVQNVTLQFPDDLIKDSSLIKFWVLADTAYSACCVDEVAAEHVAEVVVHFGDACLN-AIQNLPVVYSFGTDLALVVENFICLMANAPFLFHLTLLYLSTIFD-PALPSLMRRYKYMHVARTAGCIGILVNTLSLRNTRETINELVKLIKREKKHYLFVVGKPNVA-KLANF-EDIDIWCILGCSQSGIIVFNE-FYKPIITPYELNLALW-TGKWDFRDAPEFDVVRGRYRS-WKGLIEEGI-SGVARGY Salro FELSRCTNKIALQFPDELLHYGVTVEFYLLADTTFGSCCVDEVAAEHVADVVIHFGNSCLS-RTSRLPALYVFGKDQQALLEYVVHVLFDVRYFLFVGLMNHMLTFD-PATRQLMKRYFLIQKAKDAGTVGLVVGTLGSADYKGVTDRLRTMLRCGKKDYTLLVGKINPA-KLANF-DEIDIYCLVACPEHSLIDSAE-FYRPVITPYELELACW-GGFLDFRQLPHFSLISNAYRT-YQGLAIQGR-TGVPIQY Schco3 FDIPWTAKRTALQFPDELLRYSVPIELYVLADTSYGSCCVDEVAAKHAVDAVVHYGHACMS-QTYRLPVIYVFGKDVDDCVAKFVVLRHDVGYILYVGLTNLLMSYL-PKSRMLMRRYAAVQKARDADVFGILVGTLGVASYLPLIKHLRETLKAQKKSYTISVGKLNPA-KLANF-MEIECFVLVACPENSVIEAKE-FLRPIVTPFELQIALW-TGRYDFEQLPHFSLVTGKYRS-YQGLLEQGR-SGIARGY Schpo1 YEINRTVNSVALQFPDEHLADSGKVNVQILADTNYGSCCVDEVAAEHMADAIVHYGRACLS-PTSRLPVLYVFGRNLHKLEKCLILLVSDTRWLLYIGLSSILMSFD-PLSAKLRRRYALVQRCRDAGVIGIVIGTLGVHRYLHVLNQLRKMILAGKKPYMLAVGKLNPA-KLANF-QEIECFVLIACGENSLIDSKE-FYRPIVTPFELVKALW-NNDFSFDEVPHFSLITGKFKS-WSGLLYEGQ-SGIAKGY Sorma YEISRTARRIGLQFPDHMLCDAPRVRVYVLADTSYSACCVDEIAAEHVADVVVHYGRSCLS-PTSRLPVIYVFTKDRDAALADFVVLMADVTYIFHVSLLALCSQTS-SDS-LLGRRYARLLSLTTAGIIGILVNTLSVSNYLSSIDSIRKQIAAGKKSYTMVVGKLNPA-KLANF-AEIDGWVVVGCWESSLIEDDAGFYKPVITPFELELALW-TGKWGIEAVPEFDWRSGKLRT-WVGLIEEGR-GGVARGY Sphar -------RVVALQFPDDMLADAQCVRVFVLGDTTYGSCCVDTVAAEHVASLIVHYGESCQS-LVTKVPVLYIYGRNMDE----TVVVLYECKWVVWVGLTALMLSYN-PQTKSLMRRYFLVEKCKQAQTVGILVGTLGIAHHNELLAHIKTILKAGKKFYTIVIGKINGP-KVANF-LEVDAYVLVACAENSLVDSKE-FSVPIVTPFEMELACW-PGRLDLEEVPQLS-------------------------- Spipu1 YEIERTSSKIALQFPDELLPDSAEVEIFILADTTFGSCCVDEIAAEHGADLVVHYGRACLS-PTSRLPVLYVFGKDVHDCARAFVLLMYDVMYIFYIGLTNIILSYD-PDTKLLMRRYYMVQSAKDANVIGIVVGTLGVASYLSVINHIKRLIISGKKPYVLAVGKPNPA-KLGNF-LEIDCFVLVACPENSLLDSRD-FLRPIVTPFELELALW-TGDYDLTVLPYFSLVTGGYRT-FRGLAVDGR-RGIARGY Sporo1 YEVDLTLQRIGLQFADEQLHDAVPVELYVLADTTYGSCCVDEVAAQHVADFIVHYGHTCLS-PTARLPVLYILTKDPTHAASSLVVLLYDVGYLYWIGLTNLLMSYD-PATRMLMRRYALVEKAKDADVIGILVGTLGVAAYLPLITHLRQLIAHHKKSYTVAVGKLNPA-KLANF-IEVECFVLVACPENTMVDSKE-FLRPIVTPFELELALW-TGQYDFGELPVYSATTGKY-------------------- Stehi1 YDIDRIVKRVALQFPDELLHDSVPIELYVLADTSYGSCCADEVAAQHVADAIVHFGHACMS-KTYRIPVLYVFGKDVQDCAHKLIILRHDVAYILYVGLTNLLMSYD-PSTKLLMRRYVAVQKARDADVFGILVGTLGVSSYLPLITHLRQLLKARKKSYTISVGKLNPA-KLANF-MEVECFVLVACPENSMIEAKE-FLQPIVTPYELQIALW-TGEYDFDKIPTFSLMTGKYRS-FRGLLEQGR-SGIPKNY Tapde11 YEISHTAKNVALQFPDELLVDASSVALYVLGDTSYGSCCVDEVAAEHVADALIHYGRSCLS-PTNKLPIIYVFGKDLEDIVRKILLVVSDTTYLVYIGLTTTLMSYN-PLTIALRRRYAVVQKARDSGVIGIVVGTLGVSKYLELIRHLRTMISAGKKSYLFAMGKLNPS-KMANF-AEIDAFVLVACGENSLIESRD-FFKPVVTPYELSLALW-TGDWDFEKVPHFSLVTGRYRAHWGGLLTQGR-RGVARGY Thetr DELAPSVGVVALQFPDHLVAHAPSVEIVVLADSAYSGCCVDEVAAEHAAKALVHYGEACLT-ATLRLPVCYVFCAEVATLAEATLVVAYELSLVVFVGFTALQLTVD-VDARALMKRYMLIEKVKSAEVIGLLVGTLAVGPYLEMLDELRALIEAGRSYYTFCVGKVNVP-KLANF-TEVDVFVVVSCPLTALIDSRE-YIKPLVTPFEAFLALW-TGEYDFEQTLVTSLSSGSGRT-WRGIIEAGR-SGRAAKY Treme1 FQISLTVQTVALQFPDELLYASVAVQAYVLGDSTHGSCCPDVLSCLHLADLLVHYGHACLT-PTDALPVFYVFPRDVIQAAERLTIVVWDVSFIFYIGLVNLQMAYS-PTSKLLSRRLYAVHRAMAADVFGLVVSNIGLAASPCVLDQLRRDLKARKKSYTMSVGRLNPA-KLANF-APIDCFVLIGCNEGGVVESKD-YMAPIVTPWELRLALWTPSNWDLSTIPQFSLINGEYRQ-YKGLLEEGL-QGIARGY Trire2 YEIPRTATRVALQFPDHMLVDAPRVRICILADTSYSACCVDEIAAEHAADVVVHYGRTCLS-PTSRLPVIYVYTSDHEAVVAQFVVIMADLTYLFHISLLALQSSVP-SPSGLLRRRFARVLTLASAGVVGILVNTLSVSNYLSSIDLLRKKIAAGKKSYTVVVGKLNPA-KLANF-AEIEGWVVVGCWESGLIEEDAGYWRPVITPFEMEVALW-GGEWGIEKLPVFDLRTGKLRT-WQGLIEEGR-SGIARGY Umbra1 YEIERTCSRIALQFPDELLPDSASVSVFILADTSYGSCCVDEVAAEHVADFIVHYGRSCLS-PTSRLPVLYVFGQSVEKCVSEFIIVMYDVTFILYIGLTNIMMTYN-PEKRLLMKRYFLVQKAKDADVIGIVVGTLGVASYMTIIDHLKKLIAAGKKSYTFVMGKLNVA-KMANF-MEIDCYVLVACPENSLIDSKE-FYRPIVTPFELEIALW-TGDYDFQRLPHFSLITGEYRT-FRGLVEEGR-SGIARGY Ustma22 YDILSTAKRVALQFPDEALVDSVPVQLYILADTSYGGCCVDEVAAKHVADLVVHYGHACLS-ATARLPVIYVFTK-LEDVSAAALVLTYDVSWYLYLGLTNLLLSYN-PLTRLLMKRYACVLKARDASVVGLLVGTLGVHSYLPLLKYLRQLLTSRRKVYTISVGKLNPA-KLANF-QEIDVFVLVACPENTLVDSKE-FFRPIVTPFEMELAVW-SGKYDFERLPHFSLISGTYRG-WKGLLEEGR-QGIAKGY Walse1 FEIPRTVTRIGLQFPDELLHYSVRVKLYILADTTYNACCVDEVAAQHVADVVVHYGHACLE-PTARLPVIYVFGKDVDSCVDALTIISTDVAYIIYIGLTNIVLAFD-PTVRLLQRRYAQVNKAKDCDVFGLAVGTLSTASYLPLVKALRAKLQASKKVYTVAVGKLNPA-KLGNF-AEIQCWCVIACAENSIVNSKE-FHVPVITPFELEMALW-TGEYDFSQLPIFSASTGKFRS-WKGLLESGR-AGVARGY Zygro1 YALDEIARKITLQFPDSLVHDSSLVQFWVVADTAYSACCVDEVASEHVADVVVHFGDACLN-AVQTLPVVYSFGRDLSHVVNRFVCLMANAPYLFYINLLFLTTLYD-PKNPSLMKRYKYMHIARTAGCIGILVNTLSLRNTKETINALIELIRNDKKHYLFVVGKPNVA-KLANF-EPVDIWCVLGCGQGGIILYNE-FYKPIITPYELTLALW-TGNWDFKQVPEFDLVTGKSRA-WSGLVEEGR-SGIASKY [Cluster1791.fasta_al_trimmed; alignment length = 342] Allma1 KVLVIGAGGLGCELLKALALSG-FSDIHVIDMDTIDLSNLNRQFLFRQKDIGRPKAIVAAEFIPH-VKVTP--HFCKIQDKDTDFYSDFNIVITGLDSIEARRWMNATLVNMYTLKPLIDGGTEGFKGQARVILPRISACYECSLDMITKQT--AFPICTIAHTPRLPEHCVAWASLLQWPKRLDGDNPDHITWVYDQALARAQQYGIGVTYSLAQGVVKNIIPAIASTNAVVA--AACVLEAVKLATNNNYMMYTGGVYTYTFELERKPDCPVC--GTVGEVIELLQERVDL-QLKRPSLR-TKTLYMQNPLEQATRPNLAKPLREF-VDDTMTVTDASLP Ashgo11 RVLVLGAGGLGCELLKNLALLG-IPELHVIDMDTVELTNLNRQFLFRETDIGHPKAAVAARYIRG-VRVEP--HVGDLTQQPSAFWEGFTAVISGLDAIEPRRHANALLVRLTKCIPLIDGGSEGFAGHCKTILPGISACYECSLDTLAPPGL-AFPLCTIANKPRLPQHIVMYVLTVEWPTGCSFDDPEAVAWLAQRCATRAAAFGMAFTTAYVLGVAKRIVPSVASTNAIVA--AACCSELLKLVHDNNFLQYNGGCFAYSFTHQRLPSCPVC-------------------------------------GDGC-------------------------- Aspfu1 KIL--GAGGLGCEILKNLALSG-FKDIHVIDMDTIDISNLNRQFLFRQTDIGKPKAEVAASFVKG-VKITP--YVGKIQDKDEDYYMQFKIIVCGLDSIEARRWINSTLIGMVSLKPLIDGGTEGFKGQARVILPTLSSCIECQLDMHAPRP--AVPLCTIATIPRQPQHCIEWAHQIAWQEAFDSDDMEHISWVYNAALERANQFHIGVTFQMTQGVVKNIIPAIASTNAVIA--AATTSEALKIATSENYMMYAGGVYTYTFEAEKKADCPVC--GTLEEFIESLGERAEA-QLKKPSMR-TKTLYQRFPLEEQTRSNLKLKLKEL-VENEIAVSDPAYS Aurde31 KILVIGAGGLGCEILANLALMG-FKDIHVIDMDTIDISNLNRQFLFRPSDVGRPKAIAAAEFVPG-VTVTP--YFGKIQDKGEDYYMQFNLIICGLDSVEARRWINATLVNMVSLKPLIDGGTEGFRGQARVILPTVTSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKLDTDNPDHITWLYNLAAARAKEFKIGVTWTLTQGVVKNIIPAIASTNAIIA--ASCCTEAFKIATSNNYFMVIGGVYSYTFEHERRPNCPVC--GTVEQVIEWLIERQDI-QVKKPSLS-SKQIYFQAPLEIATRPNLEKPLSEL-IKDEVTVTAATLP Batde5 KILVIGAGGLGCELLKNLALSG-FKDIHVIDMDTIDVSNLNRQFLFRQKDVGQPKATTAAKVIPG-VQVTP--YFGKIQDKDEQYYSQFNIIVCGLDSVEARRWMNATIVGMFTLKPIIDGGTEGFKGQSRVILPRISACYECSLDMQTKPV--TFPMCTISNTPRLPEHCIEYASTVAWPKKVDGDDPTHIQWLLNTALERGREFNIGITYTLTQGVVKNIIPAIASTNAIVA--ASCANEAFKIATNNNYMMYVGGVYAYTFELQRKEDCPVC--GTLDDLIEVLLDTQEI-QLKAPSLR-TKSLFMQAPLREATLHNLKKPIKDL-VASAITVTDAHLP Botbo1 KILVIGAGGLGCEILANLALMG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGKPKATVAAEFVPG-VTVTP--YYGKIQDKDDDYYMQFNIVVCGLDSVEARRWINATLVNLVSLKPLIDGGTEGFKGQARVIFPGVTSCYECSLDMLNKPV--AFPICTIANTPRLPEHCIEWASVLEWPRKLDTDDPEHITWLYNIASTRAQEFKIGVTWALTQGVVKNIIPAIASTNAIIA--ASCCNEAFKLATQNNYFMFIGGIYSYTFEHQRRPECPVC--GTLEKLMEWLLEKQDI-QIKKPSLS-TKPLYYQGPLEEATRPNLEKLLSDL-VPNEISVTSTSLP Botci1 KIL--GAGGLGCEILKNLALSG-FKTIHVIDMDTIDVSNLNRQFLFRHSDVGKSKAEVAAKFVKG-VTIVP--HNCKIQDKDEEFYMQFSIVVCGLDSIEARRWINSKLIDMVSLKPLIDGGTEGFKGQSRVILPTMTSCIECQLDMHAPRA--AVPLCTLATIPRQPEHCIEWAHIMAWEQKLDNDDPEHITWLYKKALTRAQEFNIGVTYSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIASSENYMMYSGGIYTYTFKHEKKDDCPVC--GTLQEFIDSLAHRPEA-QLKKPSIRSAKSLYMQSPLRVKTEHNLSRKMGEM-TGDEVAVTDPSLG Caeel KILVIGAGGLGCELLKNLALSG-FRTIEVIDMDTIDVSNLNRQFLFRESDVGKSKAEVAAAFVVG-CQVTA--HNCRIEDKGQEFYRKFSIIICGLDSIPARRWINGMLCDLVTIIPMIDGGTEGFKGNARVIYPKFTACIDCTLDLYPPQV--NFPLCTIAHTPRLPEHCIEYIKVVVWPESLDADDPIHVEWVLERASLRAEKYNIGVDRRLTSGVLKRIIPAVASTNAVIA--ASCALEALKLATNDNYLNFTQGAYTSVVSMMKDDNCLTC--STLESLIIRLSERF---HLKHPTLA-TRKLYCISSFEQESKENLHTSMKDL-VSDEILVSDEALS Canalb1 KILIIGAGGLGCEILKNLAMVG-FKNLYIIDMDTIELSNLNRQFLFRMKDIGKSKAEIAAQFVPS-LNIKS--YFNKIQDKPIEFYQQFNLVISGLDSIEARRWINATLISLVYMIPLIDGGTEGFRGQSRVIIPTVTSCFECSLDLLSTKV--TYPVCTIANTPRLPEHCIEWATQIEWNDKLDGDNPEHIEWVYQTALERANEFNIGVTKHLTLGVVKNIIPAIASTNAIIA--ASCCNEAFKLITDNNYMMYTGSIHTYTFEHSKKLNC-IC--S---------------------------------------------------------------- Cangl KVLVLGAGGLGCELLKNLARYDYVSEIHVVDLDTIELSNLNRQFLFREQDIGKYKAEVAAHAI----VIVP--HVTDLTTLDATFYSQFQFVISGLDAIAPRRYVNQVLVDITICIPFIDGGVEGLKGHIKTIIPGINACWECSIDTLPHESAMNNPMCTVANNPRSLEHIVEYVVLISNPDLAV------CTQLLDQCRQRASQYGIELTLSKMAGIAKRVIPTVSTTNSIVA--AMCCEQLNCIYRDPNFTTINGGMYIFSFQYQRNPECTVC-------------------------------------L----------------------------- Capow RILVIGAGGLGCELLKDLALSG-FRNIDVIDMDTIDISNLNRQFLFRQKDVGQSKALVAAEFVAG-CKVTP--HFCKIQDKPEDFYRQFQLVVCGLDSIPARRWINALLVSLVTMIPMIDGGTEGFKGQARVILPGMSSCFECSIDTFPPQT--TFPLCTIASTPRIPAHCIEYAKIVLWPQALDTDDPEHINWLYLEALKRANEYGIGVTYRLTQGVVKNIIPAVASTNAVIA--AACASEAFKLATGNNYMQFNGSLYTFTFEYEQKPDCLVC--SPLRALVERLSEQPLYDQFKAPGI---KTFYMSAPLELSTRPNLDRTLAELGLQDFLQVADVAVP Catan2 KILVVGAGGLGCELLKDLALSG-FSDVHVIDMDTIDLSNLNRQFLFRNKDIGKAKAEVAAAFIPS-CRVTP--HFCKIQDKDTDFYSQFNLIITGLDSVDARRWMNATVVSMFTLIPIIDGGTEGFKGQARVILPKMNACYECSLDMFTKPT--AFPICTIANTPRLPEHCVSWAFVLQWPKKLDGDNPDHIQWVFDKATERANQFGIGVTYSLAQGVVKNIIPAIASTNAVIS--AACVVEAIKLTTNDNYMMYTGSVYTFTFALERKPDCPVC--GTVLELLEVLAERPDL-QLKKPSLR-TKSIYMQKPLEEATRPNLDKPLAEF-VGDEIAVTDANLP Cioin KVLVVGAGGLGCELLKDLSLMG-LRHIHVIDMDTIDLSNLNRQFLFRQCDIGKPKAEVAASFIKG-SKTFS--HFCRIQDHDSSFYKQFHIVVCGLDSIVARRWINGMLISLLSLIPLVDGGTEGFKGNARVILPGMNACMDCTLDLYPPQV--NFPMCTIAHTPRQPEHCIEYVKIFQWEKAIDGDDPDHIKWICKAASTRADEYGIGVNYRLTQGVIKRIIPAVASTNAVIA--AACANEVFKLATSNNYMVFNDGVYTYTFEAERNEQCLAC--NLLREVVDFLCQDNSL-QMKSPGLT-TKTLYMKNILEAATRPNLSKSLKDLGIVDEVIVADVTTP CocheC53 KVL--GAGGLGCEILKNLALSG-FKDIHVIDMDTIDVSNLNRQFLFRASDVGKYKAETAASFVKG-VKITP--YCGKIQDKDEAYYMQFGLIVCGLDSIEARRWINATLVGMVSMKPLIDGGTEGFKGQARVIFPTMTSCIECQLDMHAPRA--AVPLCTLATIPRQPQHCIEWAHIIAWEETLDTDDPEHITWLFNKATARAKEFNIGVTYSMTQGVVKNIIPAIASTNAIVA--ASCCNEAFKVATNDNYMMYTGSVYTYTFEHQKKDDCPVCGAGTLQEFIDGLAERPEA-QLKKPSIR-TKSLYMQL-LEEQTRPNLEKKMVDL-VEEELLITDKSFP Coere1 AVLVIGAGGLGCEILKNLAMTG-FKNIHVIDMDTIDISNLNRQFLFRTKDVGKPKAEVAAEFIPE-ISITA--HYKRIQDMPEEFYLGLSLIVCGLDSIDARRWINAYIHELAGFKPIVDGGTEGLKGNMRVILPKVNACFECGLDIYPPKV--TYPICTIANTPRLPEHCIEWASVLEWPRKLDGDNVDQINWVVEQASERAASFNIGITFSLAQGVVKNIIPAIASTNAIIA--AACTNEAFKIITGDNSLLYVGGMYFLTYPLFQNDDCIVC--GTLQQLIEALQEHNTF-QLKAPSLT-YTNLYFQGPLEEKTRPNLEKKLCQL-FESALTVTDPTLP Conco1 KILVLGAGGLGCEILKNLSLMG-VKYITVIDLDTIDISNLNRQFLFRVKDVGKYKAEVAAEFVKG-VQIEA--IVGKIQDQPEDFYSQFQLIISGLDNIETRRWINQKLFEQTQYTYLIDGGTEGLKGQARIMVPGITVCFECTLDLFPPKT--KFPLCTLANTPRLPEHCIEWASLIHWPEKVDGDNWDHIQWLYTAAKARADAHNIGVTLTLTQGVVKNIIPAIASTNAIVA--ANCCNEAFKVLTMNNYATYNGGVSSTVIEMEKSETCFVC--STLSQLLLHFKLDPKF-QAKNPSVR-TKTLYMSQPLEQSTRKNLELPLSEL-VGVQLSLTDPVFP Conpu1 KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDVSNLNRQFLFRPADVGKPKAIVAAEFIPG-VIVTP--YYGKIQDKDHEYYMQFNLVICGLDSVEARRWINATLVSMVSLKPLIDGGTEGFKGQARVILPTITSCYECSLDMLNKPT--TFPICTIANTPRLPEHCIEWASVLEWPKKLDTDDPEHISWLYGVAFKRAKEFNIGVTWSLTQGVVKNVIPAIASTNAVIA--AACCNEAFKIATSNNYFMLIGGVYSYTFEHEKREHCPVC--GTVEQLMEMLTEKQDI-QIKKPSLS-TKPIYFQQPLEKNTRPNLEKKVSDL-VAAEVTVTSTTLP Copci KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPADVGKPKAVVAAEFIPG-VTVTP--YFGKIQDKDEDYYMQFNLVICGLDSVEARRWMNATLVNMVSLKPMIDGGTEGFKGQARVILPTFTSCYECSLDMLNKQT--AFPICTIANTPRLPEHCIEWASVLEWPKKMDTDDPEHISWLYSVALKRAQEFNIGVTWSLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYFMLIGGVYSYTFEHEKRQDCPVC--GTVDQLIDLLVERQDI-QIKKPSLS-TKQLYFQAPLEEATRPNLEKKLSDF-VPPEVTVTSTSLP Croqu1 QVLVIGAGGLGCEILQNLALLG-FTNVHVIDMDTIDISNLNRQFLFRQKDVGRPKAEVAAEFVPQ-CKVTP--HYCKIQDKDDGFYMNFNLIICGLDSVPARRWINATLVNLVSLKPLIDGGTEGFKGQSRVILPTITSCYECSLDMLTPQT--AFPICTIANTPRLPEHCIEWASVLEWPRRIDGDNPDHIQWLFEKAAARAEEHKIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKLATTQNYMMYTGSVYTYTFQHEPKPECPVC--GLLERLLEYLIERQDF-QIKLPSLS-TGPLFFQSPLRQATEPNLQKKLHEL-IAD--TVTDSNLP CryneH991 KVLVIGAGGLGCEILQNLALSG-FNDIHVIDMDTIDISNLNRQFLFRESDVGKPKALVAAEFVPG-CTVTP--YHGKIQDHPTSFYSTFDVIVAGLDSISARRWINATLVQMA-IKPLIDGGTEGFKGQARVILPTITSCYECSIDMLTPPT--AFPICTIANTPRLPEHCIEWASVLEWPKKLDTDDPEHIEWLYKQAAARAGQFNIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIATANNYMMYVGSVYTYTFEHEQRPDCPVC--GTLQQLIESLSQRQDL-QVSRPSLS-FKALFWPSPVYEATKANLELPLSDL-VQDAIVLVDPALP Crypa2 KIL--GAGGLGCEILKDLALSG-FKDIHVIDMDTIDISNLNRQFLFRKDDVGKSKAECAARFVKG-VKITP--HNNRIQDFDEDFYMQFAIVVCGLDSIEARRWINATLINMVSLKPLIDGGTEGFKGQSRVIFPTVTSCIECQLDMFAPRA--AVPLCTLATIPRQPEHCIEWAHVIAWDKKLDKDDPEHITWLFQKALIRAQEFNIGVTYSLTQGVVKNIIPAIASTNAIIA--ASCCNEALKIASSENYMMYSGSIYTYTFKHEKKDDCPVC--GTLQDLIDTLAERPEA-QLKRPSIR-AKTLYMQSPLEEQTRPNLVKTLIDLGLESEISVTDPAFV Debha1 AILVIGAGGLGCEILKNLALTG-FRNIHLIDMDTIDISNLNRQFLFRPNDIGKSKAEVAANFVDT-LNIVP--YFGKIQDKPIEYYQQFDVIICGLDNVEARRWINATLVSMVNLIPLIDGGTEGFRGQSRVILPRLTSCYECTLDMINPKV--TYPVCTIANTPRLPEHCIEWASVLQWPKKFDADVPEQVDWMYKTALQRADEFNIGVTRQLTLGVVKNIIPAIASTNAIIA--ASCCNEAFKFVTNNNYMMYSGSIFTYTYPHAQKLNCPVC--GTLSKFMEEISSKQEI-SMTQPSLS-TNYLYLRHPLEEITSPNLNKKLNTL-VKPEMIITDPNLP Dekbr2 KILVIGAGGLGCEILKDLAFSG-FKDIECIDMDTIELTNLNRQFLFREKDVGKPKAVIATNFVPG-IRIAA--HYAKIQDFDADFYRQFTMIVCGLDNIEARRWINKTVVDIAQYIPLVDGGTEGFQGSVKLIIPTITACFECYMKLVPKQT--TYPLCTLASTPRLPEHCIEWAHQLEWPRPFNTDIPDHITKMFELSLKRAHQYGIGVTKAKTLGVVKNIIPAIASTNAIVA--ASCCNEAFKFITSIDTMYYNGGVVLASDKYDRLPDCPVC--GIDAKTFASKYVKAKF-SLSQPDLF--HDIYNFKNSEENTQ-NGSKRLIDI-VPFLISVIDKTLK Dicdi KVLVIGAGGLGCEILKNLALSG-FRNIDVIDMDTIDISNLNRQFLFRRKDVGKSKAEVAAAFITG-CNVTP--HKCRIQDKDEDYYRQFKIVIAGLDSIEARRWINGLLVNLVTIIPLVDGGTEGFKGQARVILPKISSCFECSLDAFPPQV--SYAICTIANTPRVPEHCIQWALLFGLQDQFDNDNPDHMNWLFECAKKRAEKFNIGVTYKLTQGVAKNIIPAIASTNAIIA--AACCNEVFKFCTDNNYMMYNGGVYTFTFEYEIKEGCAVC--GTLSTFLEKITTDSRF-QFKKPSLR-SRNLYMQG-LHQSTVPNLEKTLSELNVQEEITITDPALP Dmel QVLIIGAGGLGCELLKDLALMG-FGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFIPT-CRVTP--HFKKIQDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQV--NYPLCTIANTPRLPEHCIEYVKIIQWEKPLDGDDPQHIGWIYERALERSNEFNIGVTYRLVQGVVKHIIPAVASTNAAIA--AACALEVFKLATSANYLNFNDGIYTYTYEAEKSENCLAC--STLEDVIKLLCDSPRF-QLKSPALT-TRTLYMSGVIEEATRKNLTQSLGELGLHDQLTVTDATSP Enthi KILVVGAGGLGCEVLKALAMVG-FQNLTIIDMDTIEYSNLNRQFLFRKKDVGRPKSEVAAEFVPG-CKITH--VVGRLEDQPLSFYKSFKLVISGLDNLGARRWTSSTLCSLVTIIPLIDGGTEGFQGHVMVIVPKVGPCLDCIISLFPPQK--TFPMCTIASQPRLPEHCIVWASQIAWENKVDADNPAHVQWVYEHALQRAEEKNIGVTYRLTLGVIKNIMPAIASTNSLIA--AQTANEAFKYATGDNYLVYYGGINTSVESLEKKKGCLVC--DTLQQLVDEISDDPEL-QVSNPSIG--QIIFVSR-LKEQTEKNLVLELCQLGVKEELIINSPAIS Falba -------------------------------MDTVEVSNLHRQFLFRERDVGRPKAEVAAQVAPQ-ATVES--VCADLTQLPRSFFHRFQLILSGLDSIEARRWVNITLHRMVTAIPLIDCGSEGLSGQVRIIIPGFTSCIECQAGLYPNDETAEAPLCTLAGRPRTAGHCIAWAVQVDWPAEIQPENEAHISWLAQSAAARAQEFGIGVGRASVVATLRQATPAVVSTNALIA--GIGVGEALKLATGDDYMSFHGGVYSGTFRMMRLPGCAIC-------------------------------------LREAPAS----------------------- Fomme1 KVLVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGKSKAIVAAEFIPG-VRVTP--YHGKIQDKDTSYYMQFHIIICGLDSVEARRWINATLVGMVSLKPLIDGGTEGFRGQARVILPTVTSCYECSLDLLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKLDTDDPEHINWLYTTALARATQFNIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIATNDNYFMYIGGVYSYTFKHEQRDDCPVC--GTVQALIDALAERPDV-QVKRPSLS-TANMYLQGPLEELTRPNLEKKVIDF-VEESILVTAASLP Fusgr1 KVL--GAGGLGCEILKNLAMSG-FKNIHVIDMDTIDISNLNRQFLFRKDDVGKYKAEVAAAFVKG-VSITA--HNNRIQDFDEEFYKQFQLVICGLDSIEARRWINAMLVSIAALKPLIDGGTEGFKGQARVILPTMTSCIECQLDMHAPRA--AVPLCTIASIPRQPEHCVEWAHVIAWDKKLDKDDPEHVTWLFQKALTRAQEFGIGVTYSLTQGTIKNIIPAIASTNAIIA--AACCNEAFKIATSTNYMMYSGSIYTYTFKHEKKDDCPVC--GTLQELIESFAIRPEA-QLKKASVR-AKTLYMQFPLEEQTRPNLNKTLNELGLEDQVVVTDPAFP Galma1 KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGQPKATVAAEFIPG-VKVTP--YFGKIQDKDDDYYMQFNLVICGLDSVEARRWMNATLVNLVSLKPMIDGGTEGFKGQARVILPTVTSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKMDTDDPDHIGWLYKVAAARAAEFKIGVTWSLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYFMLIGGVYSYTFEHEKRDDCPVC--GTVEQLIETLVEKQDI-QIKKPSLS-TKQIYLQAPLEKSTRPNLEKKVSEL-VPPEVTVTATTLP Ganpr1 KVLVIGAGGLGCELLKDLALMG-FKDIHVIDMDTIDISNLNRQFLFRPADVGRPKATVAAEFVPG-VKVTP--FYGRIQDKDESYYSEFSIIICGLDSVEARRWMNATVVGMLTLKPMIDGGTEGFKGQSRVILPTMTACYECSLDMHTQRQ--AFPICTIANTPRLPEHCIEWASVIMWPKKLDGDDPEHIQWLFNMASKRAAEFKIGVTWSLTQGVVKNIIPAIASTNAVVA--ASCALEAFKLATSSNYMMYVGGIYTYTFELQRKPECPVC--GTLEDFIDTLKERKEI-QLKRPSLM-ARSLYMTHPLEERTRDNLVKRMDEL-VEEEITVTDPGLP Gloin1 KVLVIGAGGLGCEILKNLALSG-FKNIEVIDMDTIDLSNLNRQFLFRPSDVGKPKAKVAAEFITD-VKVTY--YHGKIQDKDDDYYLGYQLIICGLDSVDARRWINATLVNLVRIRVLVDGGTEGFKGQARVIIPTITSCYECSLDMLSKQR--TFPICTIANTPRLPEHCIEWASVIQWPKKMDTDEPTHIQWLYETALKRAKEFNIGVTYSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKLITNNNYMMYTGGLYTYTFEHQKKPDCPVC--GTVEDFIEYLQEKQDI-QLKKPSLS-HEKIYWQSPFEQKTRPNLEKKLIEM-VKQEITVTDTTLP Hisca1 KIL--GAGGLGCEILKNLALSG-FKDIHVIDMDTIDISNLNRQFLFRQSDVGKPKAEVAAAFVKG-VKITP--YVGKIQDKDQSYYMQFKMIVCGLDSVEARRWINSMLVGMVSLKPLIDGGSEGFKGQARVILPTLSSCIECQLDMHAPRA--AVPLCTIATIPRQPQHCIEWAHQIAWGEEFDGDDMEHITWIYNTAFERAKKFNIGVTFSMTQGVVKNIIPAIASTNAVIA--AACTSEALKIATSENYMMYAGGVYTYTFAAEQKSDCPVC--GTLEDFILSLGELPEA-QLKSPSLR-SKMLYQRVPLEEHTRPNLKQKLKDL-VADEVAVSDPALH Klula1 KILILGAGGLGCEIVKTLALYG-LPELHIVDMDTIELTNLNRQFLFSTRDIGKPKASVAAEAITGFVHVVP--HNQDLTQFNDDFISQFDIIVSGLDSIEARRWINFKLHDVTTVIPFIDGATEGLMGNCKLIVPGFTSCYECSLSTLPQNTE-TYPLCTLASNPRTLAHCIQYASIILWPRPHDLESPDDLQWLYEKSLHRAEEFNITLTTRYVLGVLKSIIPSVTTTNSIIA--GQCCKQAIDLLTDPTFTMYNGGATMFSYRHERDASCTVC-------------------------------------FA---------------------------- Lacbi2 KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGQPKATVAAEFIPG-VKVTP--YFGKIQDKDDDYYMQFNLVICGLDSVEARRWMNATLVNLVSLKPMIDGGTEGFKGQARVILPTITSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKMDTDDPEHIGWLYKVAAARAQDFKIGVTWSLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYFMLIGGVYSYTFEHERRLDCPVC--GTVEQMIEMLVEKQDI-QIKKPSLS-TKQIYLQAPLEEATRPNLEKKVSEL-VPPEITVTASTLP Lenti61 KILVIGAGGLGCEILANLALSG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGNSKAIVAAEFIPG-VKVTP--YFGKIQDKDEDYYMQFNLIICGLDSVEARRWINATLVNMVSLKPLIDGGTEGFKGQARVILPTVTSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKMDTDNPEHISWLYQIALARAKEFKIGVTYSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIATSNNYFMLIGSVYSYTFEHEKRQDCPVC--GTVDRLIEVLVERQDI-QVKKPSLS-AKQIYFQAPLEEATRPNLEKKVSEL-VPDEITVTATTLP Malgl1 RILVIGAGGLGCEILSNLALSG-FQHVHVIDMDTIDVSNLNRQFLFREKDIGQPKATTAAAFVPG-VKITP--HVCRIQDMDVTFYMQFHMVICGLDSVEARRWINATLVHMVSLKPLIDGGSEGLKGQARVILPTITSCYECSLDMLPKRT--TFPICTIANTPRLPEHCIEWASVLEWPRKLDNDNPEHVQWVLDTALGRAESFHIGVNWSLTQGVIKNIIPAVASTNAIIA--AACTQEAFKIATSNNYMMYTGGVYTFTFDYERRADCPVC--GTLATLVDLLSTLPDM-----------FAIY---------------------------------- Mellp23 QVLVIGAGGLGCEILQNLALLG-FTNVHVIDMDTIDISNLNRQFLFRQKDVGRPKAEVAAEFIPQ-CKVTP--HYCKIQDKDDAFYMTFNLIICGLDSVPARRWINATLVNLVSLKPLIDGGTEGFKGQSRVILPTITSCYECSLDMLTPQT--AFPICTIANTPRLPEHCIEWASVLEWPRKIDGDNPDHIQWLFEKASERADAHKIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKLATTQNYMMYTGSVYTYTFEHEQKPECPVC--GLLERLLEYLIERQDF-QMKQPSLS-TGSLFFQSPLRQATEGNLKKKLHEL-LADMAEVFDQH-- Mnele KILVVGAGGLGCEIIKCLAMTG-FRAVHVIDMDTIDLSNLNRQFLFTPDDIGKPKAEAAVRAVPG-LRYVA--HYNKIQDFDDDFYLQFNIVICGLDSVYARRWMNSTLLNIASIIPFLDGGTEAFKGHCRVVIPTKTACIECNMDLYPPQQ--NFPLCTIANTPRLPEHCVEYAKIVLWPKGVDGDNPDHITWLYKTAVDRAKSYNIGVTYRLTQGVTKRIIPAVASTNATIA--AACVTECLKIATSDNYMMFNNGIYTFAFTSERKENCLVC--SKLQVFLDKIGEETGF-NLKKPTLT-ARTLYMSNLMEEVLRPNLEKTFKELDFVDEVIVTDPGMK Monbr RVLVIGAGGLGCELLKDLALCG-FRRIDVIDMDTIDVSNLNRQFLFRPKDVGRDKATVAAEFIPG-CQVTP--HFNRIEDHDPDFYRQFQLVVCGLDSVAARRWINNMLLSLLTIIPLIDGGTEGFKGNARVIIPGKTACVECMLDLFPPQV--NFPMCTIANTPRLPEHCIEYAKIVQWPKKLDGDDPEHIRWLHDKAAERAGQFGIGVNYSLTQGVVKRIIPNVASTSAVIA--AACANEAFKLASSNNYVVFNDGVYTHTFEYERKPECLAC--STLTMLLDELTTRADF-QFRGPGLT-TKTLYMTRPLEEATRPNLDKTLQELGLVDIVNVTDPTSP Morel2 KILVIGAGGLGCEILKNLALSG-FCDIHVIDMDTIDVSNLNRQFLFRRADVGKPKAVTAAAFIQG-VTVTP--HYCKIQDKDEDFYSEFALVICGLDSIEARRWMNATLVGMRSLKPLIDGGTEGFKGQARVILPGITSCYECSMDMLSKPT--GFPLCTIANTPRLPEHCIEWAHILEWPNKMDTDDPKDIQWLYETALARARQYNIGVTYSLTQGVVKNIIPAIAATNAIIA--ASCCNEALKIATTNNYMMYSGSVYTYTFEHQRKDDCPVC--STLEELMDYLKEKPDV-QLKKPSFA-VKPLYMQAPLEEAMRPNLQKPLSEL-FSSELTITDSTLP Mucci2 KVLVIGAGGLGCEILKNLALTG-FKQLHVIDMDTIDLSNLNRQFLFRKKDIGKSKAIVAANFVPG-VEVVP--YFGKIQDKDDDYYRQFQLVICGLDSVEARRWINAKLVDMVSWKPLIDGGTEGFKGQARVILPTMSSCYECSLDMFNKPT--TFPICTIANTPRLPEHCIEWASVLEWPKKYDTDNPEHITWLYQQASERAKKFNIGVTYSLTQGVVKNIIPAIASTNAVIA--ASCCNEAFKLATGNNYMMYTGGVYTYTFEHQKKPDCTVC--GTVEELIEWLTEKPDI-QLKKPSLR-TKTIYMQAPLEEATRPNLSKFISEF-IEDFVTVTDVALP Mydma KILVIGAGGLGCELLKDLGMMG-FKHIHVIDMDTVELSNLNRQFLFRKKDIGKPKAEVAANFVKG-CCVIP--Y----------------------------------LFTLV--------------------------------------------------------------------------------------------FKI-------------------------------------------------SVYYITLKK---------------------------------------------------------------------------- Neucr2 -------------------------------MDTIDISNLNRQFLFRHADVGKFKAEVAAKFVKG-VKITP--YNCKIQDFDEDFYQQFQIVVCGLDSIEARRWINATLVNMASMKPLIDGGTEGFKGQARVILPTMGSCIECQLDMHAPRA--AVPLCTLASIPRQPEHCIEWAHVIAWDKQLDKDDPEHITWLYQKALERAKEFNIGVTYSLTQGVVKNIIPAIAATNSVIA--AACCNEALKIASSPNYMMYSGSIYTYTFKHEQKEDCPVC--GTLEELIESFATLPEA-QLKKPSVR-AKTLYMQLPLEEQTRPNLEKTLEQLGLTEELAVTDPAFV Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACANEAFKIATNNNYFMYIGGIYTHTFEHEKKDNCPVC--GKLKDFIQMLIERPDI-SIKKPSIC-SKPLYMQAPLEMATRPNLEKTLEEL-VDEEVIVTDPALP Pench1 KIL--GAGGLGCEILKNLALSG-FKDIHVIDMDTIDISNLNRQFLFRQADIGKPKAEVAAAFVKG-VNITP--YVGKIQDKDEDYYMQFNIVVCGLDSIEARRWINSTLISMVSLKPLVDGGTEGFKGQARVILPSISSCIECQLDMHAPRP--AVPLCTIATIPRQPQHCIEWAHQIAWQETFDNDNMEHISWIYNAAYERAQQFHIGVTFQMTQGVVKNIIPAIASTNAVIA--ASTTSEVLKIATSANYMMYAGGVYTYTFEAEKKPDCPVC--GTLGEFIDSLGERAEA-QLKKPSMR-TKTLYQRFPLEEMSRPHLGKKLADL-IEDEVAVSDPAYT Phybl2 RILVIGAGGLGCEILKNLALTG-FKNLDVIDMDTIDVSNLNRQFLFRRKDIGKPKAIVAAEFVPG-VQVTP--YFGKIQDKDDDYYRQFQTVICGLDSIEARRWINAKLVDMVSLKPLIDGGTEGFKGQARVILPTINSCYECSLDMFNKPT--TFPICTIANTPRLPEHCIEWASVLEWPRKYDTDNPEHITWLYQQAQTRAEKFNIGVTYSLTQGVVKNIIPAIASTNAVIA--AACCNEVFKIATSNNYMMYTGGIYTYTFEHQKKPECPVC--GRLDEMIDWLKDKPDA-QMKKPSLR-ILSLYMQAPLEIATRPNLSKTLSEL-LEEIITVTDASLP Picst3 TVLVIGAGGLGCEILKNLALTG-FKKIHVIDMDTIDVSNLNRQFLFRPKDVGHSKAEVAARFIEE-LKITP--YFGKIQDKPLEYYRQFGVIVCGLDSIEARRWINATVVSLVNLIPMVDGGTEGFRGQSRVILPTLTSCYECTLDLLSPKT--TYPVCTIANTPRLPEHCIEFASVIEWPKKFDADDPELVQWMYETALARAKLFNIGVTKQLTLGVVKNIIPAIASTNAIIA--ASCCNEAFKIVTNNNYMMYAGSIFTYTYAHSRRPNCPVC--GTLDRFIEEISGKQEI-QMLLPSLT-TKSLYLRNPLEQATRPNLAKKFNTL-VRAEVVITDPNLP Plicr1 KILVIGAGGLGCEILANLALSG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGKPKATCAAEFIPG-VKVTP--YFGKIQDKGDDYYMQFNLVICGLDSVEARRWMNATLVNLVSLKPLIDGGTEGFKGQARVILPTVTSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKLDTDDPEHIGWLYNIAAARAKEFKIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIATSNNYFMLIGSVYSYTFEHEKRDDCPVC--GTVERLIEMLVEKQDI-QIKKPSLS-TKQIYFQAPLEEATRPNLEKKVSEL-VPDEVTVTASTLP Polpo KILVIGAGGLGCELLKNLALSG-FRNIDVIDMDTIDVSNLNRQFLFRRKDVGKSKAEVAAAFIAG-CKVTP--YKCKIQDKDEDYYRQFKLIIAGLDSIEARRWINGLLVNLVTIIPLIDGGTEGFKGQARVILPRISSCFECSLESFPPQT--TYAICTIANTPRVPEHCIQWALIFGLPDVFDNDNPVHMTWLYETAKKRAEDHNIGVTYKLTQGVAKNIIPAIASTNAIIA--AACCNEAFKICTDDNYMMYNGSVYTYTFNYEVKEGCAVC--GLLSTFLEDISKDSRF-QFKKPSLR-CRNLYMQG-LHQSTVPNLEKSLEDLQVGEEITITDPSLP Pucgr2 KVLVIGAGGLGCEILQNLALLG-FGDIHVIDMDTIDISNLNRQFLFREKDIGQPKADVAAKFIPQ-VKVTP--HYCKIQDKDEAFYMMFNLVICGLDSVPARRWINATIVNLVSYKPLIDGGTEGFKGQSRVILPTITSCYECSLDMLTPQT--VFPICTIANTPRLPEHCIEWASVLEWPRKLDNDNPDHIQWLFEQASTRAEQHHIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKIATSKNYMMYNGSIYTYTFQHEKKPDCPVC--GFLQQLVDHLVERPDF-QIKQPSLS-TGPLFFQGPLRKATELNLDKKLLDL-FPD--TVTDSSLP Punst1 KILVIGAGGLGCEILANLALSG-FKDIHVIDMDTIDISNLNRQFLFRQKDVGKPKAIVAAEYIPG-VKVTP--YFGKIQDKDDDYYMQFNLVICGLDSVEARRWINATLVNLVSLKPLIDGGTEGFKGQARVILPTVTSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPRKMDTDDPDHIGWLYKVASARAKEFNIGVTWSLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYFMLIGGVYSYTFVHEKRDECPVC--GTVDRLIEMLVEKQDI-QIKKPSLS-TKQIYFQAPLEEATRPNLEKKVSEL-VPDEVTVTATTLP Rhior3 KILVIGAGGLGCEILKNLALTG-FKQIHIIDMDTIDLSNLNRQFLFRKRDIGKPKAIVAANFVPG-VQVVP--HFEKIQDKDDEYYKQFQLIICGLDSVEARRWINAKVLEMMTWKPLIDGGTEGFKGQARIILPTVTSCYECSLDMLNKPT--TYPICTIANTPRLPEHCIEWASVLEWPRKYDTDNPEDINWLYQHALERANEFNIGVTYSLTQGVVKNIIPAIASTNAVIA----------------------GGVYTYTFEHQKKPECPVC--GIVNQLIEYLAERSDT------------------------------------------------- Rhoto1 KVLVIGAGGLGCEILANLALMG-FADIHVIDMDTIDVSNLNRQFLFRPEDVGKSKAQCAADFVPG-CKVTP--YHGKIQDKDDDYYMQFNIVICGLDSVDARRWISATLVNLVSLKPLIDGGTEGFKGQARVILPTITSCYECSLDMLTPPT--AFPICTIANTPRQPEHCIEWASILEWPKKLDNDDPEHIQWLFDTARKRAEEFNIGVTWSLTQGVVKRIIPAIASTNAIVS--AACCNEAFKIATSNNYMMYTGSIYTYTFEHQRKPECPVC--GSLQDLIDMLLERQEF-QIRRPSLR-LKSLYLQAPLEEATRPNLEKTLAEL-MQSVVTVTDAGLP Rozal11 KILVIGAGGLGCELLKDLALSG-FTDIHVIDMDTIDVSNLNRQFLFTEKDVGNPKSVVAAQAIPS-ASITP--HYCKIQEKDESFYSQFNVIVCGLDSVSARRWINALLCQMVSIIPLIDGGTEGFKGQARVILPKLSSCFECSLEMFPPQT--TFPMCTIANTPRLPEHCIEYASVVEWPKKMDKDNAEHMKWLYETALTRANQFNIGVTYRLTLGVIKNIIPAIASTNAIIA--AACSLEVFKLVTRNNYMMYNGGVYTYSFEYERKADCVAC--GSFGDFIDHFIQNHPS-KFKTPSFR-TKTLYMQTPLEEATRPNLSKSLREL-LQETMIVTDPNLP Sacce1 KILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYV----EVVA--HVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQD-TVPMCTIANNPRCIEHVVEYVSTIQYPDTAD------MEFLLEKCCERAAQFSIKLSTSFILGIIKSIIPSVSTTNAMVA--ATCCTQMVKIYNDNNFTLINCGCFMYSFKFERLPDCTVC-------------------------------------SNSN-------------------------- Salro RILVIGAGGLGCELLKDLALMG-FRNIDVIDMDTIDLSNLNRQFLFREADIGSPKAEVAAKFIPG-CKVTP--HFSRIESKDRAFYKQFTVVVCGLDSIVARRWVNSMMHSLLSMIPLVDGGTEGFQGNARVIFPGMTACVECMLSLYTPQV--NFPMCTIANTPRLPEHCIEFARLVLWPKQIDGDNPEHITWLFEKARERAAEFGIGVTYRLTQGVTKRIIPNVASTSAVIA--AACANEVFKVVSSDNNLIFNDGVYTYAYKYDRDPDCLTC--SSLTHLRETLCTSDKF-QLRGPGLT-TKTLYMARPLEQATRPNLDKSLAELGLEHMVNVVDPTVA Schco3 KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGKPKATVAAEFIPG-CVVTP--YFGKIQDKDDDYYMQFNLVICGLDSVEARRWINATLVNLVSLKPLIDGGTEGFKGQARVILPTITSCYECSLDMLNRPT--AFPICTIANTPRLPEHCIEWASVLEWPRKLDTDDPEHIGWLYSVAAARAKEFKIGVTWSLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYFMLIGGVYSYTFEHNRRPECPVC--GTVEKLIEMLVERQDV-QIKKPSLS-TTKIYLQAPLEEATRPNLEKKLSDL-VQNQITVTASSLP Schpo1 KILIIGAGGLGCEILKDLALSG-FRDLSVIDMDTIDITNLNRQFLFNESNIDEPKANVAASMIPS-TVVTP--FYGKIQDKTIEFYKEFKLIICGLDSVEARRWINSTLVAIADLIPLVDGGSEGLKGQARVIIPTITSCYECSLDMLTPKI--SYPICTLANTPRLPEHCVEWAYLLEWPRNFEPDNIRHIDWLVKRSIERANKFQISINRFFVQGIVKRIIPAVASTNAIIA--ASCCNEALKILTEDNYMMYVGGAYTYTFNLEKRSDCPVC--GTLKDILNHYSKSY---NLQNPSVS-TTPLYLASPLQVATSKNLSQPILSITSVDNLVITDKNLS Sorma KILVIGAGGLGCEILKNLALSG-FKDISVIDMDTIDISNLNRQFLFRHADVGKFKAEVAAKFVKG-VKIMP--YNCKIQDFDEDFYLQFQIVVCGLDSIEARRWINATLINMVSMKPLIDGGTEGFKGQARVILPTMGSCIECQLDMHAPRA--AVPLCTLASIPRQPEHCIEWAHVIAWDKQLDKDDPEHITWLYQKALERAKEFNIGVTYSLTQGVVKNIIPAIAATNSVIA--AACCNEALKIASSPNYMMYSGSIYTYTFKHEQKEDCPVC--GTLEELIESFAALPEA-QLKKPSVR-AKTLYMQLPLEEQTRPNLSKTLEELGMTAEIAVTDPAFV Sphar --------------------MG----------------------------------------------------------------------------------------------------------------------------------------------------------------DLDTDDAEHTTWLFQQALARAEQFNIGVTYRLTKGVVKNIIPAVASTNSTIA--ACCANETFKLATRNNYAFINLGVYALPFEYEKDEDCIVC--STLQALIERILQ-----QLNIKEISGMNTLYMERPLRIATLPNLDKSLGELKLSSEVSITASELT Spipu1 KILVIGAGGLGCELLKDLALMG-FTDIHVIDMDTIDISNLNRQFLFRASDVGKPKAEVAANFVPG-VKITP--YFGKIQDKDEEYYNQFTIIICGLDSVEARRWINATVITMFTFKPIIDGGTEGFKGQSRIILPRMSACYECSLDMQTKPT--TYPMCTIANTPRLPEHCIEWASVLEWAKKLDGDDPEHIKWLLDKASARAKEFNIGVTYTLTQGVVKNIIPAIASTNAIVA--ASCANEAFKIATNNNYMMYVGGVYTYTFELQKKEDCPVC--GTLEDLMDLLMDRKDI-QLKKPSLR-TKSLYMRAPLEEATRPNLGKQIREL-MEDEVTVTDETLP Sporo1 KVLVIGAGGLGCEILANLALMG-FADIHVIDMDTIDISNLNRQFLFRCKDVGQPKATVAAQFVPG-CKVTP--YHGKIQDKGDDYYMQFNIVICGLDSVDARRWMSATLVNLVSLKPLIDGGTEGFKGQARVILPTITSCYECSLDMLTPPT--AFPICTIANTPRLPEHCIEWASMLEWPKKLDNDDPDHIQWLFDTARTRAEQYKIGVTWSLTQGVVKRIIPAIASTNAIVS--AACCNEAFKIATSNNYMMYTGSIYTYTFEHQQKPECPVC--GLLQDLIDLLLEKGDL-QIKRPSLS-LKNLYLQAPLELATRPNLEKTLSEL-FASVLTVTDSGLP Stehi1 KILVIGAGGLGCEILANLALTG-FKDIHVIDMDTIDISNLNRQFLFRPKDVGHPKATVAAEFIPG-CKVTP--YFGKIQDKDESYYMQFNIIICGLDSIEARRWINATLVNMVSLKPLIDGGTEGFKGQARVILPRITSCYECSLDMLNKPT--AFPICTIANTPRLPEHCIEWASVLEWPKKLDTDDPDHITWLYTVAAARAKEFKIGVTWSLTQGVVKNIIPAIASTNAIIAGMSSCCTEAFKIATTNNYFMLIGGVYSYTFEHEKRKDCPVC--GTVERLIEMLVERQDI-QIKKPSLA-SKPIYFQGPLEQATRPNLEKKVSEV-LNSTINVTSTSLP Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr RVLVIGAGGLGCELLHSLAKSG-FGELEVIDMDTIDVSNLNRQFLFRAADVGKYKADVAAAFVPG-VS-------------DDAFYRSFNLIIAGLDSIKARSWISAKLVSLATVIPLIDGGTEAFKGQARVMLPRISACFQCSISAFPPQR--AFQLCTIANTPRKPEHCIAYAMNVLWEAVLDKDSVEDVTWVMTAAAARGAEYGIGITYQLTQGVMKNIIPAIASTNALIA--GACVLEAIKIATNDNWFMYIGGINTRTFAWERDESCSVC--GTLGELRSSLVDDAAL-QLVSPSLR--KTLYMET-LKKLTQANLDKTLSEV-VSSEISVTDANGA Treme1 KILVIGAGGLGCEILQNLALTG-FNDIFVIDMDTIDISNLNRQFLFRETDVGKSKALVAAEFVPG-VKVTP--YHGKIQDHPPSFYMQFDIIIAGLDSISARRWINATLVQMVSLKPLIDGGTEGFKGQARVILPTISSCYECSIDMLTPPT--VFPICTIANTPRLPEHCIEWASVLEWPKKLDTDDPEHIEWLYQQASTRAAEFNIGVTWSLTQGVVKNIIPAIASTNAIIA--ASCCNEAFKLATTNNYMMYTGSIYTFTFEHERRPECPVC--GTLERLVEWLSARQDL-QISRPSLA-HQPLFFQAPLYEKTRPNLDKLVSAL-LPNQIVVTDPGLP Trire2 -------------------MSK-FKDIHVIDMDTIDISNLNRQFLFRKSDVGKYKAEVAAKFVKG-VKITA--HNKRIQDFDDEFYKQFQLVICGLDSIEARRWINAMLVSIAGVKPLIDGGTEGFKGQARVIFPSFTSCIECQLDMHAPRA--AVPLCTIASIPRQPEHCIEWAHVIAWEQKLDKDDPEHVTWIYQKALKRAEEFNIGITYSLTQGTIKNIIPAIASTNAIIA--AACCNEAFKIATTNNYMMYSGSIYTYTFKHEKKDDCPVC--GALQDLLDSLAVRPEA-QLKKPSIR-AKTLYMQVPLEQQTRPNLSKSLKDLGLENEVVVTDPAFP Umbra1 KILVIGAGGLGCEILKNLALTG-FNDIHVIDMDTIDVSNLNRQFLFRSADVGKSKALVAAEFVPG-VKIIP--YMGRIQDKDEDYYSQFQIVICGLDSIEARRWINAMLVSLVSLIPMVDGGTEGFKGQARVILPTITSCYECSLDMFNKPN--SFPICTIANTPRLPEHCIEWASVLEWPRKYDTDNPEHISWLYETALTRAKKFNIGVSYFLTQGVVKNIIPAIASTNAIIA--AACCNEAFKIATSNNYMMYTGGVYTYTFEHQKKPECPVC--GILEDFLDVLKEKPDT-QLKKPSLR-TKALYMQAPLEKASRPNLVLKMGDL-VEDEITVTDVALP Ustma22 SILVIGAGGLGCEILSNLALTG-FYNIHIIDMDTIDVSNLNRQFLFREKDVGRSKAHVAAEFVPG-VQITP--YHGKIQDKDEQYYKQFNIIVCGLDSVEARRWINATLVNMVSLKPLIDGGTEGFKGQARVILPTVTSCYECSLDMLNKQT--TYPICTIANTPRLPEHCIEWASVLEWPRKLDNDNPDHISWLLEHASTRAASFGIGVTWNLTQGVVKNIIPAIASTNAIIA--AACVLEAFKFATTNNYMMFTGSVYTYTFEHEKRPDCPVC--GTLERLIEQLGELTDL-QIKKPSLS-LKPLYYQAPLEHATRPNLQMKLVEL-CEQEITVTDARLP Walse1 KVLIIGAGGLGCEIVANLALTG-FSDLHIIDMDTIDVSNLNRQFLFRSSDVGKSKAKAAAEFIPN-VKVTA--HHNKIQDFGEDFYMQFNIVVCGLDSVEARRWINATLYNMVSLKPLIDGGTEGFKGQSRVILPTISSCYECSLDMLTPPT--TFPICTIANTPRLPEHCIEWASVLEWPKKLDNDDPEHIEWLLSKSLSRAKEFNIGVNWSLVQGVVKNIIPSVASTNAIIA--ASCCNEAFKIATTNNYMMFIGGVFTYTFEHQKRENCVVC--GIVEDLIDILKQRQDF-QVRKPSLS-NGNIYLQYPLEEYTRQNLTKPLSEY---KTILVTDANLP Zygro1 KVLVLGAGGLGCELVKNLAVLK-VREIHVVDLDTIELTNLNRQFLFKDEDIGRYKANTAVDYLRS-IKLVA--HCQDLFTLQPDFYKYFDFVISGLDAVGPRRFVNRTLVQLTICVPFIDGGTEGLNGHVKTIVPGVTACWECSIDTLPQQQT-QHPLCTIANNPRNLEHVVEYVATVQLAGGV----------LLKLCYERATQFGIKLTESYAWGVAKHIVPSVSSTNAVVA--GLCCNELVKIYNDKNFKTISAGLYINSFQFDRLEDCPVC-------------------------------------L----------------------------- [Cluster1815.fasta_al_trimmed; alignment length = 144] Allma1 MKIVGLTGGIATGKSSVSRHLAAVPVIDCDQLARQVVEPGTSALDRAKLGAIIFADEAKRHILNRITHPAIRRAILAKVIVVVDAPLLIEAG-LCNEVVVVYCQLQRLMKRDMPQADAEARMRAQKPMDEKTRVLDNRQADALL Ashgo11 MLVIGLTGGIACGKSTVSRRLHEIPVIDADAIAREIMRPGERALNRAALGAWIFQHAEERQALNAITHPEIRKRIFFRVVCVLDIPLLFETG-LCGVTVSVVCQIERLLLRNLTREEAEARIRAQMSMEERDYVIPNETVDQAV Aspfu1 MLIIGLTGSIATGKSTVSALLASLPIIDADLLARQVVEPGTPALNRPALGRRVFGTSEERMILNKIVHPAVRWEIYKALIVVLDVPLLFESG-MCGTVVVVGVQMARLRSRDLSAEDAENRVRSQGDVRGKGVIVWNKEVSKAM Aurde31 MLVVGLTGGIATGKSTVSTQFRGFPVVDADVLARRVVEPGTPALDRKALGDIIFRDAAKRRVLNAIVHPAVRRAMLWEIACIVDVPLLIESN-LVGKVLVVYCQLQRLTQRDSTEEQALHRLNSQMPIDEKDEVIDNVQVVRMA Batde5 MRIVGLTGGIATGKSTVSSFL-TIPVVDADLIARQVVLPDTPAINRTDLGALIFSNSELREKLNHITHPYIRLEMLRQVICVLDTPLLFEAK-LVHTVVVVYCQRERLMRRDITVIQAQQRIDSQMPIDRKDYVIDNEQTLNLM Botbo1 MLVIGLTGGIASGKSTVSHLLASIPIIDADVLARRVVLPGTRALDRAKLGAIVFNDESMRRRLNAIVHPAVNRAMLWAVVCVVDVPLLVETG-SVGKVVVVYLQLQRLTKRDSTPTAALARLNSQLPLASKDHVIDNAQVDALV Botci1 MLLIGLTGSIATGKSTVSSILSQLPIIDADLLARKVVEPGTPGLNRPALGRRVFGDSEERAVLNGIVHPAVRKEMYKQLLVVLDVPLLFESG-ICGTVLVVAVQMQRLRDRDLTEEDAENRVKSQGDVREKGLVVWNIELQKVM Caeel -----------------------------------------------------------------------------------------------------------MVTRDISRADAESRIHAQMDIEEKKIVIDNEKVKHVI Canalb1 MLIVGLTGGIACGKSTVSKELKDLTIVDADLVAREVVYPNKPALNRAALGQAVFGNKEKLAILNSIVHPAVKWEIFKQIIVILDVPLLYESG-LCGLTVTVSCQIERLLARNLSESDANKRIESQMSNKERDIVLDNESIKCLV Cangl MLILGLTGGIACGKSTVSRRLKEYPIIDADQIARDVVEPGQSALNRAALGKWVFAHKDDLQVLNNITHPAIRKRIFKDILCVLDVPLLFESH-MCGVSVAVTSQLERLMVRNLTNEDAQNRIKSQMSMAERDYVIENGQLDNLI Capow MLLIGLTGGIATGKSTVSKMLQDIPVIDADLIARQVVEPGKPAINRDALGKLIFNDADKRRQLNGAVHPAVFREMFRQILAVLDVPLLFEGGQLLRRVVVVYCELQRLMARNMSEADARSRMNAQMSIEEKDIVIDNNQVRAVF Catan2 MKIIGLTGGIATGKSSVSLHLRAIPVIDCDLLARQVVEPGTPALDRAKLGELIFNDPAKRRLLNAITHPAIRRAILARVIVVVDAPLLVESG-LMSEVVVVYCQLARLMHRDLDASAARARISAQAPMADKTHVIDNTQVDALV Cioin MFLVGLTGGIASGKSTVSKYLVECSVVDADLVAREVMLPGETAINREALGEIIFRDAEARKKLNKITHPQIIKKMLLKILVVLDVPLLVESKIWVRHLVVVNCQLERLMKRNYTEEEARIRITSQTPLSEKTRIINNCQVREFV CocheC53 MLLLGLTGSIATGKSTVSSLLSKLPIIDADRIARQVVEPGTAGLNRPALGRRVFGAGEERKMLNSIVHPAIRREMYKQMVVVLDVPLLFESG-WCGTILVVGVQIQRLRARDLTEEDARNRVMSQGDVREKGVVVWNKEVQRVM Coere1 MLVIGLTGGIATGKSTASKAFRAVSVIDADAIAHELMEPGQVSIDRAQLGKLIFNDAKQRQALNRFTHPYIRRRILWRVFCVVDVPLLFEAG-LCGRTLVVSCQIARLMERNLSRPEADARVAAQMPMAEKTRVLDNAQVRTVL Conco1 MKIIGLTGGISTGKSTVSKELQILPLIDCDLLARVVVEPGKPALNREKLGDFIFKNPAQRRQLNKITHWYIRLEIAKSLIVVIDAPLLIEAG-IVSELWVVYTQLERLIARNFTEEDAKNRINSQLSLETKTRVIDNLQVETIV Conpu1 MLVVGLTGGIATGKSTVSNLFKELSVIDADIIAREVVQPGTRGLDRKKLGAIIFNDPFKRKQLNAIVHPAVSRAILWSVLCIVDVPLLIEGG-MMGRVVVVYCQLQRLMKRDSSREDASSRLHSQLPISDKDIVIDNTQLSSCL Copci MLVVGLTGGIATGKSTVSTLLKAIPIIDADLLARQVVEPGTPALDRKKLGSVIFNDEAKRKQLNNIVHPAVRKAMLFEVVCILDVPLLIEGP-LVGLVVVVYCQLQRLVSRDCSREDALSRIHSQLPIADKDVVLDNKQVDALV Croqu1 YQVIGLTGGIASGKSTVSTLLKSIPIIDLDLLAREVVKPGSSALNRTKLGDIIFSDPIQRKWIDSLLHPRIKRLMLYQIVCVIDSPLLIETG-MCGKIIVVYCQLKRLMSRNIDEKIAKQKMKSQLPLKSKDYILENSQVERLV CryneH991 MLIVGLTGGIASGKSTVSKLLSELPIIDADLIAREVIEPGTSGLDRGAIGDIIFHDPEERKWLNGVVHPRVKKEMVKRIIVIVDVPLLIEAG-MVGDTVVVYVQLSRLLSRQLTQSQASSRIASQLPLSAKTSVIDNDQVDRTV Crypa2 MLIIGLTGGIATGKSTVSSILSSLPIIDADVLARQVVEPGTPGLNRPALGRRIFGDAPERARLNAIVHPAVRRAAYWALLVVWDVPLLFEVG-TCGAVVVVGVQMARLRARDLTAEDAENRVRSQTDVRVKGLVVWNREVERAM Debha1 MLIVGLTGGIGAGKSTVSRTLHELTIVDADLIAKEVVNPCRKALNRAALGSAVFGNKEKLKRLNSIVHPAVRREIIWQIIVVLDVPLLFEAG-LCGVTVTVTCQVKRIAARNLSEGDIRKRIDSQMSNEERDVVIDNKSVASVV Dekbr2 MLVVGLTGGIASGKSTVSAQLHDFPIIDADKIAREIVEPGKPALNRPALGRYVFSNKSELQILNSITHPEVRKEILRRILCILDVPLLFEAG-MCGKTICVICQLQRLMKRNLTKEDCINRIHNQLSNKERDIVIENIELDKDI Dicdi LIKIGLTGGIASGKSTILGYLKEIKCIDADKFGHMVYQKGRPSIDRSKLGPIVFSDPLKMKQLTNIVWPEMKELILNEFKVVLEAAVLIEAG-FVDLIWVTQVAIERLKTRNLSEVDACKRIDSQLTNEERNLVFKTNEINNLL Dmel MFIVAVTGGIATGKSTISKVFERIPVIDADKIAREIVEPGQPCINRAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCIVLDLPLLFETGVLIHKIVCVTCQLERLIARNLSESEARHRVDSQMPLDKKHFVIDNSSAMSIY Enthi VFVIGITGRICSGKSTLSKTLIKIPVIDCDKLGHELYQKGSIVIDRKKLSELVFSNPQNVKIISDLTWPAIYTLLQERIKVGVEAALLIRAN-WVNVIWETRITIKRLKTRNLSEEQAKKRIQSQPTQEEYQVQINTKEVDKLL Falba MILVGVTGGIATGKSSAIRLLSEWPVVDTDAISHAITAPNAPILDRAALGRLIFQDPAARSLLGRVMQPAIRLRTAAGAACLLDVPLLFEGN-LCHVSVLIDCQLQRLLFRGGDVEQALNRIGSQMPLSQKTYILPNQQVLLFL Fomme1 MLVVGLTGGIATGKSTVSSLLKSVPVIDADVIAREVVQPGRRALDRPKLGAAIFGDEGKRKKLNSIVHPAVRREMAWQVACVIDVPLLIETG-LVGLVVVVSCQLQRLVGRDLSEEAATARFKSQMPIAAKDIVIDNGRVNKLV Fusgr1 --------------------------------------------------------------------------MFKSVVVVLDIPLLFESG-LCGVAAVVAVQMQRLRARDLSAEDAENRVRSQTDVREKGIVLWNVQLDKAI Galma1 MLVVGLTGGIATGKSTVSSMLKAVPIVDADVIARQVVEPGTPGLDRKKLGSIIFNDETKRKQLNKIIHPAVRKAMLWQVICIMDVPLLIEGP-LVGLIVVVYCQLRRLMQRDSSKEDASSRLNSQIPISQKDIVIDNGQVDSLI Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------ Gloin1 MKLIGLTGGIASGKTAVSRMIIRLPLIDGDLLAREVVEPGKPALDRAKLADIIFSDEQKRKILNRCTHPYIRRKIFKLLAVVLDAPLLIESG-LMSAVVVIYVQLHRLIKRDIQEHAALQRISAQMPIREKDHVIDNRQLNVVL Hisca1 MLLIGLTGSIATGKSTVSALLSALPIIDADLLARKVVEPGTPGLNRPVLGRRVFGDTAERAVLNRIVHPAVRWEIYRALLVVLDVPLLFESG-LCGTVVVVGVQVARLRARDLSAEDAEARVKSQGDVRGKGLVVWNAAVREAM Klula1 MLIIGLTGGIACGKSTVSSRLKTIPVIDADAIARRILDPGQNAINRAALGAYIFANPEERKVLNGITHPEVRHAILLKILCILDVPLLFEAN-LCGITVCVVCQLQRLMERNLTEELALARIEAQMSMYDRDYLIDNGNIDGLL Lacbi2 MIVVGLTGGIATGKSTVSNLLRAVPLIDADVIARQVVEPGTPALDRKKLGTIIFNDEEKRRKLNGIVHPAVRWAMLWLVLCVLDVPLLIEGS-LVGKVVVVYCQLLRLMLRDSSREDASSRLNSQLPIAEKDIVIDNAHVDALV Lenti61 MLVIGLTGGIATGKSTVSSLLRALPIVDADILARKVVEPGTPALDRAKLGRIVFADEAKRKQLNAIVHPAVRRAMFWSILCILDVPLLIEGG-LVAKVVVVYCQLRRLMKRDSSREDASARLNAQIPITEKDVVIDNRQVDQFV Malgl1 MIIVGLSGGIASGKSTVSRILREIPLVDLDEIASLVVQKDSPTLNRGELGRLAFSSKERTRALNRITHSAIRRVLIWRLIVVVDTPLLIEVG-LCAEVVIVW------------------------------------------ Mellp23 FLVIGLTGGIASGKSTVSSILKSIPIIDLDLISRQVVEPGTKSLNREKLGSIIFANPTERKWLDKTLHPKIRRLMLFQICCVIDSPLLIETG-MCGKVILVYCQLERLMSRNLDKPTAQQKIQSQLPLKSKDYILNNSKVKDLI Mnele MRLIGLTGGIASGKTSVAAVLKEVAILSCDAAAKQVVEQGCTGIDRVKLGDLVFKNKENRDALNKCIHPEIAKIIRRHIIVVVDIPLLYESCNILHSIVVVYCQKTRLMDRNFSEEEALARINSQLSLEEKDHVVDNRQVAELV Monbr CRPFGLTGGIAAGKSTISQLFRAAVIIDADDIARGVLEPGTWGVDRQALREAIFATPAVRRVVNQATHLPVFVELLRQLIVVLDAPLLLESG-LCHTVVLVTARIERVMRRDVTETQAKATIAVQMVPAEQQVVFENNRVDAWL Morel2 MKVVGLTGGIASGKSTVAKTIQSIPLIDCDLLARLVVEPTHACLDRYKFGTIIFSDAAQRRIANGIIHPAVRDEILKRLFVVVDVPLLLEGE-LVSEVIVVYCQLERIKTRDLSEEDALARINAQRALIEKDHVIYNNATLKVM Mucci2 MKLIGLTGGISTGKSTVSALLREIPIIDADKIARDIVEPGRKALDRPKLGQIIFQDPEKRKILNRCTHPYVRLEMLKQAFVIFDVPLLIESK-LMSTTVVVYCQLQRLRKRDLSEEQALQRMKAQMPMSEKDIVLDNIQVKNMT Mydma ------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 MLLIGLTGSIATGKSTVSSLLSSLPIIDADLLARKVVEPGTAGLNRPALGRRVFGDSPERARLNSIVHPAVRKAMALAVLVVLDIPLLFESQ-LCGTVLVVGVQMERLRARDLSQEDAENRVRSQGDVREKGCVVWNEQVRRVF Orpsp11 --------GIATGKSSVSNHLKEIPIVDADKIAHDVIK-NKNIIVREKLGKIVFNNDEKRKALNEITHPKIKLDMFTEVLVIMDVPLLFESG-TVNKTVVVSCQLNRLMLRNFTKEEALSRINAQMSLEEKNKVIDNKQVDNLL Pench1 MLIIGLTGSIATGKSTVSSILSTLPIIDADLLARKVVEPGTAGLNRPALGRRVFGSTEERQVLNGIVHPAVRWEVYKALIVVLDVPLLFESG-MCGTVIVVGVQTARLRARDLTAEDAENRVRSQGDVRTKGVVIWNVAVKGAM Phybl2 MKFIGLTGGIASGKSTVSKLLLEVPVIDADLIAREIVKPGRRSIDRPKLGDIIFKDPHKRSILNQCTHPYVRLEMAKQALVVFDVPLLFESK-LMGTNIVVYCQLQRLRNRDLTEEQASNRIQSQMPLSEKDIVLDNTQVRNMI Picst3 MLIVGLTGGIATGKSTVSKQLVELTVVDADLIAREVVYPGKSALNRAALGKAVFGNKERLAKLNAIVHPAVKWEIARQILVILDVPLLYESG-LCGLVITVSCQIHRLLARNLTTEDAEKRVNSQLPIEIRDLVIDNRSVDSIV Plicr1 MLVVGLTGGIATGKSSVSSLLKALPVVDADVIAREVVAPGTPALDRKKLGSIIFNDDAQRKKLNSIVHPAVRRAMFTAVLCIMDVPLLIEGP-LVGKVVVVYCQLQRLMKRDSSREDASSRLNSQIPISEKDMIIDNAHVDQVV Polpo MIKIGLTGGIASGKSTVLKYLTEAKCIDADKIGHAVYKKGEPAIDRRSLGPIVFADKQNMNTLCSIVWPEMKVLIEKEFQVVLEAAVLIEAG-FVDRVWVTSIAISRLSARNLSEEEAIKRIDSQLTNQERDVVFDTTEYNKLI Pucgr2 MLVVGLTGGIASGKSTVSGLLKSVPVIDLDHLAREVVEPGSSALNRERLGEIIFNNPSERQWLNNLLHPRIRRLMVLRLICVIDSPLLIETG-MCGKVVIVYCQLQRLQSRNLSRAEAKSRIAAQMGLKSKDHIVDNRQVERLV Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------ Rhior3 MKLVGLTGGISTGKSTVSSMLVEIPIIDADKIARDVVEPGRKAIDRPKLGQIIFQDPEKRKILNKCTHPYVRLEMLKEAFVVFDVPLLIESK-LMSYTVVVYSQLKRLKERDLTDELAMQRIKAQMSMAEKDIVIDNIQVKNMA Rhoto1 MLVVGLTGGIASGKSTVTSLLKSVPVIDLDILARVAVEPESYALNREALGSIVFNNEKERKVLNSIVHPAVRRLLAWELACVVDAPLLIEAG-LCGAIVVVYCQLQRLRSRNLSLADAQARLSSQRPLSEKDYVIDNNQVDSVV Rozal11 MYIVGLTGGISSGKSQASLKFQEIRVIDADLISHKLLQPNSPIIDRKKLGKIVFDSETKRKILNSIMHPAIKKRIIGDVIIVLDIPLLFETG-LVNETIVVFCQIERLIHRDISKEDAMIRLKSQMPLNKKDVVFDNDQVVSYV Sacce1 MLVVGLTGGIACGKSTVSRRLRDLPIVDADKIARQVVEPGQNALNREALGKWVFSHKEDLQALNGITHPAIRYAMFKEIGCVLDVPLLFEGN-LCGVTVSVICQLERLMTRNLSEEDAKNRLNSQMSTEERDYILQNEQIESVV Salro FRVIGLTGGVGCGKSTVCKMLTEAVVIDADAISHNVLLRGRWGVNRSVLRQIAFEDRSVSRKLNKALHLPIGFELLQQLLVVLDAPLLLETG-LCKWVITVSCQVQRVMGRDTTAEDARRIIATQMPLEKKDHIIANQRVDACV Schco3 MLVVGLTGGIATGKSTVSKLLRDIPIVDADVLARQVVEPGTPALNRKALGEIIFNDAEKRKVLNGIVHPAVRWAMVRAIACVTDVPLLIESG-IVGQTVVVSCQLERLMLRDSTEEAARARINAQMSMAEKDVVLDNAQVEELL Schpo1 MLILGLTGSIATGKSTVSREFQEIKIIDADVLARKVVEPNTPCLNRAKLGQAVFQDAGKRSLLNSIIHPAVRLEMLKELLVILDVPLLFEAK-MCWKTICVSCQKQRLLARNLTAEDAENRVQAQMPLELKDIVIENENIHNVL Sorma MLLIGLTGSIATGKSTVSSLLSSLPIIDADLLARKVVEPGTAGLNRPALGRRVFGDSPERARLNSIVHPAVRKEMALAVLVVLDVPLLFESQ-LCGTVLVVGVQMERLRARDLSAEDAENRVRSQGDVREKGVVVWNEQVREVF Sphar MKIIGLTGGIASGKSTVSQQLTQIPVIDADKIAREVVEPGQPALDRPKLGQRVFGDEAARKQLNKITHPAIQNLMIKRMMVVLDVPLLFESRVLCSNTVCVYCELERLMRRDLGREDAEKRIGSQMPLEDKDYIIDNERVEELV Spipu1 MKLIGLTGGIATGKSTVSNYLSSVPIVDADIIARDVVKRNEPGLDRPKLGSIVFGDAEARKKLNKATHPPIRMEMLRQLLCVLDTPLLFEAG-LVHDVVVVYCQKGRLISRDLSAEQAQSRIESQMPIEKKDIVIDNQQVDSAI Sporo1 MLVVGLTGGIASGKSTVSSILKSVPLIDLDVLARVAVEPNSYALNRDKLGSIVFNDPKERKVLNSIVHPAVRRLLAWELLCVVDAPLLIEAG-LCGAIVVVYCQIQRLRARNLSLADAQSRLGAQHALSSKDFVIDNAQVDRVI Stehi1 MLVIGLTGGIATGKSSVSKLFKDIPVVDADIIARQVVLPGTRALDRPKLGAIVFNDEQKRKKLNDIVHPAVRREMLWQVVCVLDVPLLIESG-IVGKVVVVYCQLQRLMKRDSSREAASSRLNSQLPITDKDYVIDNDQVSTFV Tapde11 MLIVGLTGGIATGKSTVSKLISEIPIVDADILARKVVEPGESALNRPALGRRIFNDDAARKTLNGITHPAVRRAMTLAALIVMDVPLLFEGG-LCGKTVVVACQMKRLLARDLTKEDATSRVRSQMPILAKDIVIENARLDQV- Thetr PIVVGLCGGIACGKSSVREELAKAATIDADKVGHELYTPGHPVVDRKALGAAVFGNKDAMKQLTDIVWPAIASNLERRITTIIEAAVLLEAG-WVDEVWVVSVAVARHA-----------RIDSQMSNDERHRSIDTAVWDALQ Treme1 PPVVGLTGGIASGKSTVSSLLSTIPIIDADILAREVVAPNTSGLDRVALGEIVFHDEDERKWLNGVIHPRVRKSIVWKVLVVLDVPLLIEAG-LVGEVVVVFVQISRLLSRPLSITQAQARISSQMPLSQKTCIIDNTQVDRLI Trire2 MLIIGLTGSIATGKSTVASLLASLPIVDADVLAREVVEPGTRGLNRAVLGRLVFGDEPQRAVLSGIVHPAVRLGMVKKVAVVLDVPLLFESR-LCGTTMVVAVQLKRLMDRNLSREDAENRVKSQMDVRLKGVVLWNAALDEEM Umbra1 MKLIGLTGGIGSGKSTVSRIIAEVPIIDADLIARQVVEPGRRAIDRPKLGAIIFGDSDKRKVLNSCVHPYVRLEMFKQVFVFLDVPLLFESK-LVNTTVVVFCQLQRIVKRDMTEEAATQRIRSQMPLSEKNIVLDNIQVKNLV Ustma22 MLVVGLTGGIASGKSTASYLISSIPIIDLDVLAREVVAPGQAALNRAELGRLAFATPEKTKLLNKITHGAIRRRMVKKLLVVVDTPLLVEAG-LCGEMVLVYCQLKRMLKRDLSEEDAEQRLKAQLPLEEKDAVLDNLQVDKLV Walse1 MLVVGLTGGISTGKSTVSQRLQNIKVIDMDLVARQVVEPGTPALDRPALGRILFADKSEKKWIEGVLHPVILKKTAWEVLVVLDVPLLFEAS-LIGISTLVYCQLERLMIRDITHEEAANKVKSQIPIDEKDEIIYNTRIDEVV Zygro1 MLVVGLTGGIASGKSTVSRRLQEIPVIDADKIAREVVEPGQSALNRPALGKWVFSHKEDLQVLNQITHPAVRYSIFKSILCVLDVPLLFEAG-LCGVSVTIVSQLERILVRNMSKEEAINRINSQMQNEQRDYVLTNKEIDAFL [Cluster1817.fasta_al_trimmed; alignment length = 161] Allma1 FGIVGKDFVAVASDMSS-IRSIVVMKLNKHNVLLYTGEPGDSVQFAEYIQKNIQLYGIRLSTAGCASFTRRALADSLRSRGAYSTNLLIAGWDPRLYWIDYISSVPFACQGYGSYFCYSTMDRPDLSKDEAVALIKKCISELKTRFVANIKIIDKDGITQT Ashgo11 LGIRVQDSVILATSKAV-TRGISVLKLSPHSLMSFSGEPGDAVQFSEYIQANMQLYMIRLSPQAQASYVRSELAKSLRSRKPFQVNVLIGGYDPELYQIDYLGTLPYAAHGYSGFYTFSLLDHPDMTTEEGLKLLKLCVEELQRRMPIDVKVVDKDGIRDV Aspfu1 LGITGKDFVILAASKAA-MRGPTILKLSQHTLMAFSGEAGDTVQFAEYIQANVALYTMRLRPNAVANFVRGELARSLRSRNPYTVNLLLGGVDPHLYWIDYLSAVPYAAHGYAQYYCLSILDKPDISLEQGMKLLQMCTDELKRRLPIDVKVVTKDGVKEA Aurde31 FALTGKGYVLIAADMTS-ARSIVKMKLSPHLLMTYSGEPGDTVQFAEYVERNLRLYQIRLRPHSAASWIRRTLADSLRSRSPYSVNLLVGGYDPHLYWIDYLGTVPFAAHGYGSYFALSLLDRPDASLEEGIEVLKRCIDEVQKRLIVGVRVVDKDGVREI Batde5 LAITGKDFVLTAADDTT-ARSIVVMKLTNHTLMVYSGEAGDTVQFAEYIQCNSRLHSIRLSTNAIASFTRMELATSLRSRNPYHVNVLIAGANPELYWIDYISNLKFAAHGYASYFCLSTMDRENITQEEAIALLKKCLAELRVRFIGNVKIVDKNGIKEV Botbo1 FGLVGKGYTLIASDTNS-ARSIVKMKLTPHLCMAYSGEAGDTVQFAEYVERNLRLHQIRLRPPSSAAWIRRVLADSLRSRKPYQVNLLLGGYDPHLYWIDYLGTVPFAAHGYGAYFALSTLDRPTADLEQGLETLKRCIEEVQKRLIVGVKIIDQDGVREL Botci1 LGITGKDFTIIAASKAA-MRGATILKLNQHTLMAFSGEAGDTIQFAEYIQANAQLYSMRL---------------------PYAI-------DLSLYWLDYLASLPYAAHGYAQYYCLSILDKPDIDFEQGMKVLRMCTDELKRRLPIDVKVITKEGIKEL Caeel VGISTENYVILAADKATFAYGAILADLGKKLTMMCIGEEGDVAQFGDWTKRNLQLYSVRVSPSCAHHFVRRSIAEGLRSQDHYTVDVLIGGYDAFLGSVDYLANQPYLFRGFCGRFCYAIMDRKDMTEAEGLALMNKCIGEAKRRFVANVVIIDKKGYRKL Canalb1 LGIKVSDGTLIATSKAA-TRGISILKLNAHNLIAYTGEAGDTVQFAEYVQANIQLYSMRLSPKATASFVRNQLASSLRSRKPYQVNCLIGGYDPSLNWIDYLGTLPYGAHGYAAFYTTSLLDKKDMTVEDGLKLMDMCVKELQTRMPIDIKVVDKDGIRQI Cangl LGIRVQDSVILATSKAV-TRGISVLKLSPHTLMTFTGEAGDTVQFAEYIQANMQLYSIRLSPSAVSSYVRQELAKSIRSRKPYQVNVLIGGYDPELYQIDYLGTLPYAAHGYSGFYTFSLLDHPDMTTTEGLELLKLCIAELQKRMPIDVKIVDKDGVREV Capow IAISGKDFVVAAADAMA-ARSIVVMKMSPHLLQVCNGPSGDVVQFSEFIQKNIKLYQMRLSPHAAAHYTRDQLARALRSSGAYQVNLLLAGYDAELYFMDYLAAVPFGAHGYASHFVLSLLDRPEVTLDEALRLMKMCIAEVQKRLVINVRVVDAQGTRDV Catan2 FGITGKDFVVVASDMSS-IRSIVVLKLNKHNVLLYTGEPGDSVQFAEYIQRNVQLYSIRLNTQGCAAFTRRALADSLRSRGAYSTNLLIAGYDPKLYWIDYISSVPFACQGYAGYFCYSTMDRPDLSKDEAIALIKKCISELKTRFVANIKVIDAKGIETT Cioin IGFKCHDFVLIAADTAA-ARSIVMFKLGKSTIMSVTGDSGDSNQFSEYIQKNLQLYKMRMSTKGMANFTRKTLAEALR-KNPYNVNLLMAGCDCSLYFMDYLASVPFAAHGYGSYFVLSLLDRPDLTRDEAVILLRKCMEELKKRFIVNIRIVDKDGI--- CocheC53 LGITGKDFTLIAASKAA-MRGATILKLNKHTLMAFSGEAGDTVQFAEFIQANVQLYSMRLSPAATANFVRGELASALRSRKPYTVNLLLGGYDPTLYWIDYLASLPYAAHGYAQYYCLSLLDKPDIDYEQGLKIMRMCTEELKRRLPVDVKAITKDGIKDV Coere1 FAIIGKSFAISVTDKSV-AHSIVKMKLTPHTLMSVTGVPGDTSNFSEYIQGNVRLYGIRLSPSETANFIRGELANALRSRRPHQVNLLVMGYDSSLYWIDYLSAVPFAAHGHCSYFVLSVMDRPDITLEQGFDIIKKCIAAVKMRFPINIKVVDSNGIREV Conco1 --------------------------------------------------------------------------------------MLIGGWSPKLYWLDYLGSVPFAAHGYGAYYVLSLMDRPDLTVEEAKVLMGKCLKELQTRFIINFKLVDSTGTHEV Conpu1 FAITGKGYVIIAADTTA-ARSIVKMKLSPHLLMAYSGEPGDTLQFAEYVERNIRLYQIRLRPAAAASWIRRTLADSLRSRSPYQVNLLVGGYDPSLHWIDYLGTVPFGAHGYGSYFALSLLDRPEASLEEGLDTLRRCINEVSKRLVVSVKVVDKDGTREV Copci FAITGKGYTIVAADTTA-ARSIVKMKLGPHLLMAYSGEPGDTVQFAEYAERNIRLYQIRLRPSAAASWIRRALADSLRSRNPYSVNLLLGGYDPHLYWIDYLGTVPFAAHGYGAYFALSLLDRPEASLEEGLETLKRCIDEVAKRLVVSVKVVDKDGVREI Croqu1 FGITGKDFVIFASDSSA-ARSIVKMKVSKHVVMAYSGEPGDTVQFAEYVERNLRLYGIRLLPHEAASWTRNQLASSLRSRKPYSVNMLLGGYDPMLYWIDYLGTVPYAAHGYGAYFCLSTMDRPDMNLEQGLALLKRCIDELSTRFIANIRVADKDGVREV CryneH991 FGITGKDYVILASDMGA-GRSIVRMKLGPHLAMAFSGEPGDTNNFAEYIERNMRLYNIRLLPPAASAWVRRTLAEAIRSRHPYAVNLLLGGFDPHLYWIDYLGTVPYAAHGMGVYVSLSTMDKEDMDKREGVDLLRKCIDETEKRLTIKCILIDKNGIHKV Crypa2 LGITGKDFTLIAASKAA-MRGVTILKLNKHTLMAYVGEAGDTVQFAEYIQANAQLYSMRLSPSALANFVRGELASSLRSRKPYNVNLLLGGVDPSLYWLDYLASVPYAAHGYAQYYCLSILDKPDITLAQGLKILQMCADELKRRLPIDVKAVTKDGIVPI Debha1 LGIRVQDSTIIATSKAA-TRGISVLKLNTHNLVAFTGEAGDTVQFAEYIQANIQLHTMRLSPKATASFVRNQLATSIRSRKPYQVNVLIGGYDPSLNWIDYLGTLPYAAHGYAAFYCTSLLDRKDMKFDEGLKLLKECLKELETRMPIDIKVVDKEGIKVV Dekbr2 IGIRVNDGVIVATSRAC-TRSITILKLNEHNILAYTGTSGDTTQFADYIQGNMQLYSMRLNSKGIASYIRHELATSLRSRSPYQVNILLAGLDPFLSNIDYMGTLPYAAHGYAAFYVMSLFDRPDMTLKDGMKLLKMCKAELDERFPVVVKVVDKEGIHSS Dicdi LAFKVKGGVLCLADSSV-NHSIVKMKIDGHKLLLSAGEAGDRVQFTEYISKNIKLYSLRMSTPAAANFIRNELATSIR-SHPYSINLILAGYDTSLYYMDYLGSLNFGCHGYASYFLLGLLDRCDLSLEDGINLMHLCTTELKTRFLVSLKFVSSEGIKVL Dmel LGIKGPDFVMLASDTMQ-AKSLVFMKLSDFNMMATVGDGGDTIQFTDFISKNLHLYKISLSAKSAAHFTRKTLADYIRTNTRYQVAMLLAGYDPDLHYIDSYGAINHAGHGWGSMFCGSILQRSKLSQEDAYSLMKKCVLEIQRRLIINVYVVDSKGMRKM Enthi IGIVGKDFVLMAVDGNS-GRGVITVRVQGNRLLTIIGEGNDRQVLADFVQRNIALNYYRSTTQSIAHWIRRQVSDSLR-EGGYQCSMLLGGVDPELFMIDQFGTETYASHGIGSNFVYALLDKSGMEFEEALELMKKCIKEIQKRVIVSIEVCYKDKTELI Falba ISLTGKDYVLTASDMTA-ARSILVFKLSPHITMAFCGESGDTVQFAEFIQKNIRLYAIRLSPKAAANYVRTQLAESLRSRSPYAVNVLIAGFDPELYWLDYLGTIPFGAHGFASNFVLSTLDNPDMDLEQGIALLKSAIKVVQQRMLISIKLVNKDGVSVI Fomme1 FALVGKGYVLVAADMKV-ARSIVKMKLGPHLVMTYSGEPGDTVHFAEYIERNLRLHQIRLRPSSAAAWIRRALADSLRSRSPYAVNLLVGGFDPNLYWIDYLGTVPFAAHGYGSYFVLSLLDRPDATLEEGLATLKRCIDEVAKRLIDGVKVVDKDGVREV Fusgr1 LGITGKDFTIIAASKAA-MRGATILKLNKHTLLAFSGEAGDTVQFAEYIQRNAQLYSMRLSPSALAHFVRGELATSLRSRKPYNVNLLMGGVDPSLYWLDYLASVPYAAHGYAQYYCLSILDKPDITLHQGIKILTMCIDELKRRLPLDVKAVKADGIVDI Galma1 FALTGKGYLIMAADTTA-ARSIVKMKLSPHLLMAYSGEPGDTIQFAEYVERNIRLYQIRLRPAAAASWIRRALAESLRSRKPYTVNLLLGGYDPHLYWIDYLGTVPFAAHGYGAYFALSLLDRPSASLEEGLATLKRCIDEVSKRLVVSIKVVDKDGVREV Ganpr1 LGIVGKDYTLLAADAVS-ARSIVVMKLNDHNLMVFTGEPGDAVNFAEFIQANLKLYEIRLSTKAIASYTRRELADSLRSRNSYAVNLLIGGVDPELYWMDYLGAVNHGAHGYAAYFCSSVFDRADMSLDEGIALLQKCLHELRTRLVVNVKVVDSNGIREI Gloin1 ------------------------MKLNKHIVMLYSGEPGDTVHFAEYIQRNVRFYEIKLTPKAAATFTRKELATSLRSRHPYAVNLLIAGYDSQLYWIDYLGSVPFAAHGYGAYYTLSLLDRPDLSLDEAKILIKKCIDELKSRFIINIKVADKDGVREI Hisca1 LGITGKDFTLIAASKAA-MRGATILKLSKHTIMAFSGEAGDTVQFAEYIQANVQLYSMRLSPSAVASFVRGELARSLRSRRPYTVNLLLGGVDPSLYWLDYLAAVPYAAHGYAQYYCLSILDKPDITLEQGLMLLEMCTDELKRRLPIDVKVVRKDGIEEV Klula1 LGIRVKDSVILASSKAV-TRGISILKLLPHTLMSFSGEAGDTVQFAEYIQANMQLYLIRLSPHAASSFVRTELAKSLRSRKPFQVNVLIGGYDAELYQIDYLGTLPYAAHGYAGFYTFSLLDREDLTVDEALGLLKQCVQELELRMPVDVKIVDKDGVRVV Lacbi2 FAITGKGYVIVAADTTS-ARSIVKMKLSPHLLMAYSGEPGDTVQFAEYVERNIRLYQIRLRPSAAASWIRRALAESLRSRKPYSVNLLLGGYDPHLYWIDYLGTVPFAAHGYGSYFALSLLDRPEATIEEGLATLKRCIDEVAKRLVVSVKIVDQDGIREV Lenti61 FALTGKGYVILASDTTA-ARSIVKMKLSPHLLMAYSGEPGDTVQFAEYIERNIRLYQIRLRPPSAASWIRRTLADSLRSRKPYAVNLLIGGYDPHLYWVDYLGTVPFAAHGYGAYFALSLLDRPEAPLEEGLKTLRRCLDEVAKRLVVTVKVVDKDGVREI Malgl1 FGITGKGYTIIASDGNA-ARSIIKMKLSKRLVMAYAGESGDTIQFAEYIERNMRLYSIRLRPKAAASWIRSQLAEAIRSRHPYQVNLLLGGYDPALYWVDYLGTVPFAAHGYASYLTLSTMDRPDMSLDEGLKLLKQCIEEMRKRFVIDVRVITRDGVHEV Mellp23 FGITGKDFVIFASDSCA-NRSIVKMKVSKHVVMAYSGEPGDTVQFAEYVERNLRLYGIRLLPHEAASWTRNQLATSLRSRKPYSVNMLLGGYDPMLYWIDYLGTVPYAAHGYGAYFCLSTMDRPDMNLEEGLALLKRCIDELNTRFIANIRVADKEGVREV Mnele IGICGKDFVVMASDNLA-AHSIIAIKLGDKMIMAVSGDAGDMSNYAEYIQKNLKLYEMVLTPNAAANFARKVMAQSLRSRGPYMVNLLLAGVEPSLYFMDYLASEKFAAHGYGSFFILSTLDREDMTKEEAVDLLKLCIREVQSRFIVNVKIIDKEGITDV Monbr LGLVGADFVLVAADTAQ-IRSVVRMKLTDKTMMLLAGSVGACSNFGDLMAKNIKLNGIRHSPAECANFVRKSLADALRTREAYQVNLLLGGYDPELYYIDYFGAVPFGAHGYGSFFTLATLDREGMNFEEAKDVMRKCIEEVRTRFIVNVRVIDREGTHEV Morel2 FGITGKDFVITAYDSKA-VASITLMKLNPHTLMLFSGEPGDGVHFSEYIERNIKLYGIRLSPRAVASFARRELADSLRSRKPYSVNLLIAGFDPSLYWLDHLASVPFAAHGYGAYYCLSLLDREDITEEEGIKLLQKCVGELRSRMILNAKVVNKDGIRIV Mucci2 FGITGNGFTLLAADTIS-ARSIVVMKLNAHTVLLYTGEPGDTVNFAEYIQRNIKLYGIRLSPKATATFTRRQLADSLRSRHPYSVNLIIGGYDPELYWIDYLGALPFCAQGYGAYFCTSLMDRENMNVEEAKKLMGMCIQELKTRFIVNVQLVDKDGVHQV Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LGITGKDFTIIAASKAA-MRGATILKLNKHTLMAFSGEAGDTVQFAEYTQANAQLYSMRLSPSALANFVRGELATSLRSRKPYNVNLLLGGVDPSLYWLDYLASVPYAAHGYAQYYCLSILDKPDITLHQGIKLLNLCTDELKRRLPIDVKAVTKDGIIDI Orpsp11 LGIQGKDFVLVASDALA-ITSIVAMKLNNNVLLMFSGEGGDTVQFCEFIQRNVQLNGIRLSTKAAANFTRIELAESLRSR--------------------------------------------------------------------------------- Pench1 LGIAGKDFVILAASKAA-MRGPTVLKLNKHTVMAFSGESGDTVQFAEYIQANAALYSMRLSPSAVANFVRGELARSLRSRSPYTVNLLLGGIDPHLYWVDYLASLPYAAHGYAQYYCLSILDKPDCSLEEGLALLTLCTDELKRRLPIDVKVVTKDGVREI Phybl2 FGITGKDFVLVAADTVS-ARSIVVMKLNSKTIMLYTGEPGDTVNFAEYIQRNIKLYSIRLSPKATANFTRRELADSLRSRHPYSVNMLIGGYDPELFWIDYLGALPFAAQGYGAYFCTSLMDRPDMNLEEVKDLLRRCIQELKTRFIVNVQLVNKDGISEL Picst3 LGIRVADGTIIATSKAA-TRGISILKLNKHNLVAYTGESGDTVQFAEYVQANIQLYSMRLSPKATASFVRNQLATSIRSRKPYQVNVLIGGYDPSLNWIDYLGTLPYGAHGYAAFYANSLLDKKNMDVEQGLALLKMCLKELETRMPIDVKVVDKDGIRSI Plicr1 FAITGKGYVIVASDTTA-ARSIVKMKLSPHLLMAYSGEPGDTVQFAEYVSRNIRLYQIRLRPSAAASWIRRALADSLRSRKPYSVNLLVGGYDPLLYWIDYLGTIPFGAHGYGAYFALSLLDRPEASLEEGLATLKRCIDEVSKRLVVSVKVVDKDGIREV Polpo LSFVVADGVLCLADSNI-NHSIVKMKLDEFKLLSSAGEPGDRTQFCEFIAKNLKLYQLRLSTSATAHFIRNELATALR-RNPYNVNLLVAGYDPAVYYMDYLASLDFGCHGYAAYFLLGLLDRKDMSYEEGVELMHKCCEELQTRFLVGLKYISKDGIQVV Pucgr2 FGITGKDYVIFASDSSA-NRSIVRMKVSKHVVMAYSGEPGDTVQFAEYVERNLRLYGIRLLPHEAASWTRNQLASSLRSRNAYSVNLLLGGFDPLLYWIDYLGTVPYAAHGYGAYFCLSTMDRPDMDLQQGLELLKRCIDELSTRFIVNVRVADKDGVREV Punst1 FAITGKGYVIIAADTTA-ARSIVKMKLTPHLCMTYSGEPGDTVQFAEYIERNLRLYQIRLTPPSAAAWIRRSLAESIRSRKPYAVNLLLGGYDPHLYWIDYLGTVPFAAHGYGSYFALSLLDRPEATLDEGLATLKRCIDEVAKRLVVSVKVIDKDGVREV Rhior3 FGITGNGFTLLSADTVS-ARSIVVMKLNAHTVLLYSGEPGDTVNFAEYIQRNIKLYGIRLSPKATATFTRRELADSLRSRHPYSVNLIVGGYDSELYWIDYLGALPFCAQGYGAYFCTSLMDREDMSVDEAKTLMKMCIQELKTRFIVNTTFIDKDGVHSI Rhoto1 FGITGKDYVLFASDTSA-ARSIVRMKLGKHLVMAYSGEPGDTIQFAEYIERNLRLYQIRLRPPSAASWVRTQLASSLRSRKPYSVNLLLGGYDPSLYWIDYLGTVPYAAHGYGAYFSLSTMDRPEGDLEAGLELLRKCIKELEVRFIVNIRVADKDGVRQI Rozal11 FGIVGKDFVLIAADKSQ-VRSIVVMKLNDNIVMACAGEPGDTSSFGEFIQANVQLYSTRMSTKETAHFTRSSIAKSLRSRNPYQVNMIIAGYHPELYWIDYMGTLPFAGHGYSAYFNLSLLDRANMSLEEASSVLGMCFQELKTRFMVNVKVIDKDGIREH Sacce1 LGIRVQDSVILASSKAV-TRGISVLKLSPHTLMSFAGEAGDTVQFAEYIQANIQLYSIRLSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDPELYQIDYLGTLPYGAHGYSGFYTFSLLDHPDMTTEEGLDLLKLCVQELEKRMPMDVKIVDKDGIRQV Salro IALVGKDFVLTAADSAS-ARSIMRMKLSSHALMLLAGPVGDCSNFGDYIQANLKLQALTASTHATANYVRKNIADALRSRGAYQVNSLIAGVDPSLYYLDYLGTVPYGAHGYGSFFTFATLDHEGMSLEEATDVLKKCFLEIKTRFLMNVRVVDADGIREV Schco3 FALTGKDYVIVAADTTA-ARSIVKMKLSPHLLMAYSGEPGDTVQFAEYVERNIRLYQIRLRPSAAASWIRRSLAESLRSRHPYSVNLLVGGFDAHLYWIDYLGTVPFAAHGYGSYFALSTFDRPDATVEEGLATLKRCIDEVALRLVVSVKIVDKNGIREL Schpo1 LAVQGQDFVLTASSSSA-VRGITVLKLNSHNLMLYCGEAGDTTNFAEYIAANISLYTLRLSPEATASFTRKQLATSLRSRKPYQVNILLAGYEPELFWLDYLATVPYACQGYSSFYCLSIFDRPDLTIDEAVRIMKLCFDELKKRMPIDCKVVDKDGIREI Sorma LGITGKDFTIIAASKAA-MRGATILKLNKHTLMAFSGEAGDTVQFAEYIQANAQLYSMRLSPSALAHFVRGELATSLRSRKPYNVNLLLGGVDPSLYWLDYLASVPYAAHGYAQYYCLSILDKPDITLHQGIKLLNMCTDELKRRLPIDVKAVTKDGIIDI Sphar LGIVGDGFTVMVADKTA-ARSIMVLRLNKNTLMSLAGPIGDCTVFGEYIRANVQLFELRMTSHACANFTRNELAKALRSRNAYQCFSLIGGFDASLHWMDYLASLQYGAHGYGAAFTLGLLDKPNMTLDEVIEIVKACMLELKTRFIISFRVVDKDGIREL Spipu1 FGIVGKDFVVTASDRTS-ARSIVIMKLNKHTLMLYTGEAGDTVQFAEYIQRNIQLYGIRLSVHATANFTRRELAESLRSRNPYHVSVLIAGTDPELYWLDYLGAMNFAAHGYASYFCMSTMDREDLSVEEAISLLKKCIAELKTRFIAQVKVVDKNGVREI Sporo1 FGITGKDYVLFASDTSA-ARSIVKMKVGKHLCMAYSGEPGDTVQFAEYVERNLRLYQIRLRPPSAASWVRTQLAQSLRSRKPYSVNLLLGGFDPSLFWIDYLGTVPYAAHGYGAYFALSTMDRPDGTLEEGLELLRKCVNELETRFIVNVRVADKDGVRLV Stehi1 FALTGKGYVLMASDTTA-ARSIVKMKLTPHLLMAYSGEPGDTVHFAEYVERNLRLYQIRLRPQSAASWVRRSLAESLRSRHPYSVNLLLGGYDPHLYWLDYLGTVPFAAHGYGSYFALSLLDRPDGTLEEGLDVLRRAIDEVAKRLVVSVKVVDKDGIREI Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr LGFVGDGFTIIATDAGQ-TRSIMRIKLDEYKIMGCAGDAGDRTHFAEFVAKNLKLYELRLTTAEAAAWTRKALADALR-RKPWQVNTLIGGYDASLYFMDYLAAVPFGAHGYGAYFTYGLMDRPNMSEDEILAILDACIAELQTRFMVSVKKVDASGVTVL Treme1 FAITGKDFVLIASDMSA-GRSIIQMKVGPNLAMACGGEPGDTSRFADYVDRNLRLYHIRLPPPSAASWVRRILAESIRSRSPYAVNVLLGGFDPHLYWLDYLGTIPYAAQGVGMYVTLSTMDKENIERREALDVLNKCVDEVKKRVTIKCVLIDKDGVHSL Trire2 LGITGKDFTLIGASKAA-MRGATILKLNKHTLLAFSGEAGDTVQFAEYIQRNAQLYSMRLSPSGLAHFVRGELATSLRSRNPYNVNLLMGGVDPSLYWLDYLASVPYAAHGYAQYYCLSLLDKPDITLGQGIKLMTMCIDELKRRLPIDVKAIKADGIVDI Umbra1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 FGITGKGYTIIASDSNA-ARSIVKMKLSDHLVMAYSGEPGDTLQFSEWIERNSRLYSIRLRPKSAAAWIRKQLAESLRSRNPYQVNYLLGGFDPALYWIDYLGTVPFAAHGYGAFFAMSTLDRPDMSLEEGLDLLRRCINELKQRFIVDVRVVDREGARIV Walse1 LALTGKDYTLIVSDTNA-AMSIIRMKLGEHLVMAYNGEAGDTIQFAEYVERNLRLHSLRLQPKASASWIRRQLADSLRSRKPYAVNLLLGGWDPELYWIDYLGTVPYACHGYAAFFATSTFDRPDMSLEEGLELMKRATNEVEKRLIVNARIITQDGVREV Zygro1 LGIRVQDSVILASSKAA-TRGISILKLSPHNLMSFGGEAGDSVQFAEYIQANIQLYAIRLSPLAVSSFVRQELAKSIRSRKPYQVNVLIGGYDPELYQIDYLGILPYAAHGYSGFYTFSLLDHPDMTTEEGLKLLKMCIKELDKRMPIDVKIVDKDGIRQV [Cluster1819.fasta_al_trimmed; alignment length = 205] Allma1 RVLVGVKRVIDYNVKIAVVKHSVNPFDEIAIEAAVQAKEVIAVSCGPPK--AQESLRTALAMGADRAIHVEEPLAVAKLFKKIDLVILGKQAIDDDANQTGQMLAGLLNWQGTFASKILVVTREIDGGLETILPAVVTADLRLNTPRFATLPNIMKAKKKPI-KKDL-GV--DRLEILKVEEPPKRQGGGRVANVDELISKLKNE Ashgo11 RILVPIKRVIDPQLRPRIVQFSVNPFDDIAVEEAVRIREIHAVSIGPAK--AQEALLTAMAKGADSSTLVDEPLAVAKILRELDLVIMGKQATDSDNNNTGQMLAGLLNWQATNAARVATVTREVEGGEEVVLPLVVTTDLRLNTPRYVTLPNKMKAKKKPM-AKAFPGV--DRLNLLRFEEPPARAPGTVVASVDELLAKLR-E Aspfu1 RILVPVKRVIDYAIKPRIVKHSLNPFDELSIEEAVRLREILALSAGGAK--CVDTLRTAMAMGADRAFHVEEPLTVAKMLQAVNLVLLGKQAIDGDQGQTGQMLAGLLGWQATQASKVVEVTHEVDGGVETLLPMVITTDLRLNEPRYASLPNIMKAKKKPL-EKDF-GV--ERLKTIKVTEPPARQGGGKVEDVDGLIGKLK-E Aurde31 KVLVAVKRTIDYAVKIRVVKHSMNPFDEIAVEEAVKLREIRVVTLGPPK--ASEILRTAMAMGADTAVHVEEPLGVAKALAELDIVILGKQAIDDDAGQTGQMLAGLLGWQATFASKLAVVVREIDGGGEEILPLVLTTDLRLNLPRYASLPNIMKARKKPI-EKQL-GV--DRLETLKVTEPPKRTGGTKVENVDQLVEKLK-A Batde5 RVLVGVKRVVDYAVKIRVVKHSMNPFDEIAIEEAVRLKEVIALTVGPAK--SQETLRTALAMGADKAIHIEQPLQVAKLFKAIGLVILGKQAIDDDAGQTGQLLAGLLNWQGTFASKIILVTREIDGGLETLLPAIVTADLRLNEPRYATLPNIMKAKKKPL-EKDL-GV--DSIETLSIAEPAKRAGGKKVESVDELISKLKNE Botbo1 RVLVPIKRCVDYAVKIRVVKHSMNPFDEIAVEEALRLREIKVLTIGPPK--SQETLRTALAMGADEAIHVEEPLGIAKAIAAVDIVIMGKQAIDGDEGQTGQMVAGLMGWQATFASSVLNVNTEIDGGAEEVMPAVITTDLRLNTPRYASLPNIMKAKKKPL-TKEL-GV--DILETIKVTEPPKRVGGGKVENVDELVAKLK-E Botci1 RILVPVKRVIDYAVKPRVVKHSMNPFDELSIEESVRIREILAFSAGPTK--SQDILRTAMAMGADRSLLVEEPLGVAKLLQKVNLVFLGKQSIDDDAGQTGQMLAGLLGWQATQASKVVEVTKEVDGGTDVVLPMVITTDLRLNEPRYASLQSIMKAKKKKL-EKDW-GV--DRLKTLKVIEPPPRQGGGKVDDVDGMISKLK-E Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------MKAKKKPL-KNDL-NV--DQTETLEVTEPPVRQAGGFVDDVSALVAKLK-E Canalb1 RILVPVKRVIDFAIKPRIVKFSINPFCDIALEESLRLREIHAVSIGPLK--SQDILRTALAKGADNSTLIEEPLQVAKLIKKINLVILGKQSIDDDFNQTGQILAGLLNWQATNASKIVLVTREIDGGEDILLPMIITTDLRLNEPRYASLQNIMKAKKKPL-TKDL-GI--DKLEILKIEEPPIRQAGVKVDNVDQLIEKLK-E Cangl RILVPVKRVVDFQIKPRVIKFSINPFDDIAVEETVRIKETQAVSIGPAK--AQDILRNCLAKGIDNVSLIDEPLAVAKVLKNINLIIMGKQAIDDDFNHTGQMLAGLLNWQATNAAKVVRITREIDGGEETLLPLIITTDLRLNTPRYVGLPNLMKAKKKPM-EKDFADI--DRLEILSVNEPNAKEPGITVGSVDELVQKLK-D Capow RVIVGVKRVVDFAIKARVVKHSMNPFDEIALEQGIRLKEVIAVSCGPTA--CQETLRTALAMGADRAIHVPQPLAVAKIFKKLNLVLFGKQAIDDDANQTAQLTSALLNWQGAFAAKLVKVVREIDGGLETILPAVVSADLRLAEPRYASLANIMKAKKKPL-DKEL-GV--DRIKTLSVEEPPVRKAGIKVENVDGLLQKLRTE Catan2 RILVGVKRVIDYNVKIAVVKHSLNPFCEIAIEEAVRAKEVIAVSCGPAK--AQEVLRTALAMGADRAVHVEEPLAVAKVLAKVDVVMLGKQAIDDDANQTGQMVAGILGWQATFASKVLTVTREIDGGLQTILPTVVTADLRLNTPRFASLPNIMKAKKKPL-AKDL-GI--DRLEILKVEEPPKRQGGGRVASVDELIDKLKNE Cioin RVLVGVKRVIDYAVKIRVVKHSMNPFDEIAVEEAIRLKEVIAVTCGPTQ--SQETLRTALAMGADRGIHVEGPLQISKIFAKLNLIILGKQAIDGDNNQTAQMTAAVLDWQGTFASELLTVVREVDGGLETIMPAVVSADLRLNEPRYATLPNIMKAKKKKV-AKDL-GV--DSIEILEVADPPQRLAGIKVENTEELVGKLK-E CocheC53 RILVPVKRVIDYAVKPRVVKHSMNPFDELSIEEAVRMREIVAFSAGVAK--SQDILRTAMAMGADRGIHVVEPLGVAKLLRKVNLVILGKQAIDDDAGQTGQMLAGLLNWQATQASKVVEVVQEVDGGVQTILPMVITTDLRLNEPRYASLPNIMKAKKKPL-EKDY-GL--DRLKTVKVTEPEPRKGGVKVEDVDGMISKLK-E Coere1 RILVGVKRVVDSAVKVRVVKHSMNPFDEIAVEEALRLREIIALSCGPTK--SQETLRTALALGADRAIHVKEPLTVAKLFSKIDLVILGKQAIDDDSNQTGQMLAGLLNWQATFASKVLEVVREVDGGLETVLPAIVTTDLRLNEPRYASLPNIMKAKKKPL-QTDL-GV--ERLQTLKVTEPPKRQGGKIVASVDELLEKLR-E Conco1 RILVGCKRVIDYAVKIRVVKHSMNPFDEIAVEEAVRLREIVAVTCGPTK--AQETLRTALAMGADRAIHVEQPLAVSKLLKAVDLVILGKQAIDDDAGQTGQMLAGLLNWQATFASELVTVKREVDGGLDVILPTVLTTDLRLNEPRYASLPNIMKAKKKPL-AKDL-GV--DRLTTLEVKEPPKREGGRKVESVDELLDKLKNE Conpu1 NILVPVKRAVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKVVTIGPAK--SAETLRTALAMGADGGIHVEEPLGVAKTLRAIDIVILGKQAIDDDMGQTGQMLAGLLNWQATYASKVAHVTREIDGGAEEVLPVIITTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GV--DILETLKVTEPPKRVGGGKVENVDELITKLK-E Copci -------------------------------------------------------------MGADSAIHVEEPLAVAKTLKAVDMVILGKQAIDDDYGVTGQMLAGLMGWQATFASKVVKVTREIDGGGEEVLPVVITTDLRLNEPRYASLPNIMKAKKKPL-EKAL-GV--DQLKTLKVEEPPKRVGGGKVGSVEELVGKLK-E Croqu1 RVLVPIKRTIDYAVKIRVVKHSMNPFDEIAVEEAIRLREITLLTITNNKKGGQEVLRTGLAMGADDAILVEEPLAVSKTIAAIDLIICGKQAIDDDCSQVGGMLSGLLDCLAQYISKIAQITREIDGGVEELLPAVVTTDLRLNEPRYASLPNIMKAKKKTI-TTDL-GI--DHLEVLKIEEPPKRKGGLKVDDVDAVISKLK-E CryneH991 NILVPVKRSIDYAVKIRVVKHSMNPFDEIAVEEAIRQRDITALSIGPPK--AADTIRTALAMGADTGIHITEPLSVAHAIKAIDLVFMGKQAIDDDTGATGGMLAGMLGWQGSFASKVIEVTREIDGGLEVVIPMVITTDLRLNEPRYASLPNIMKAKKKKI-ETDL-GL--DRLETVSVTEPPKRQGGGKVETVQELVAKMK-E Crypa2 RILVPVKRVIDYAVKPRVVKHSMNPFDELSIEESVRIREICVISAGPTK--AQDVLRTAMAMGADRAIHVDEPLTVAKLLKKANLVILGKQSIDDDAGQTGQMLAGLLGWQATQASKVVSVTREVDGGVETVLPMVVTTDLRLNEPRYASLPNIMKAKKKPL-EKDF-GV--ERLKVLKVTEPAPRQGGGKVEDVDGLVAKLK-E Debha1 KILVPVKRVIDFAIKPRIVKFSINPFCDIALEESIRIREIHAVSIGPTK--AQDILRTALAKGADSTTLIDEPLTVAKLLQKTNLVILGKQAIDDDSNQTGQMLAGLLNWQATNASKVITVTREIDGGSDTLLPMIVTTDLRLNEPRYASLPNIMKAKKKPL-EKDL-GI--ERLETLKVEEPPQREAGVKVESVDELISKLK-E Dekbr2 RILVPIKKVIDAALKPRIVKFSINPFDDIAIEEAAKIKKIHAVTIGSGK--ARDVLRTALAKGADTSVLVDEPLAVSKILQKINLIIMGKQAIDDDAGQTGQMLAGLLGWQATNASRVVEVDQEIDGGIRTVLPMVITTDLRLNTPKFVPLPKMMKAKRKPL-EVDL-GI--NRLETVSLQEPSVRKAGVKVGSVDELIAKMK-E Dicdi KILVPIKRVVDYAVKIRVVKMSMNPFDEIAVEEAIRIKEIIAVSMGPKT--SQETIRTAIAMGADKGIHVEQPLSVAKLLKELNLIILGKQAIDDDCNQTAQMLAGLLNWQATFASK-VHVTREIDGGLETLLPAIISCDLRLNEPRYAKLQNIMKSKKAEL-KVSL-NV--DNLKIISVEEPPKRSGGVKVESVENVVEALKKH Dmel RVLVGVKRVIDYAVKVRVVKHSMNPFDEIAVEEAVKLKEVIAVSVGPAQ--SQEVIRTALAMGADRGVHVEQPIHVSKILAKLDLVILGKQAIDDDANQTAQMTAAVLDWQGTFCNKILTITREIDGGLETITPAVLSADLRLNTPRYATLPNIMKAKKKPL-KKDL-GV--DRIEVISVEDPPVRQAGATVADVDALVAKLK-E Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba RVLVGCKRVVDHAVRIRVVKHSLNPFDEIGVEEAVRLKE-----------------------------------------------LAGEQA-----------------------------------------------------------------KKKKV-ETEL-DV--DRLETTRVEEPAPRQGGGRVADVAELISKLR-G Fomme1 NILVPVKRCIDYTVKIRVVKHSMNPFDEIAVEEAVRLREIKALTIGPPK--AVDTLRTALAIGADAAIHVEEPLAVAKVIRAVDLVIMGKQAIDDDAGQTGQILAGLLDWQATFASKVANVVREIDGGLQEVLPLVVTTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GV--DRLETIRVSEPPKRVGGGKVSSVEELVAKLK-E Fusgr1 RILVPVKRVIDYAVKPRVVKHSMNPFDELSVEESVRIREICVISAGPPK--AQDVLRTAMAMGADRAIHVEEPLTVAKLLQKANLVVLGKQSIDDDANQTGQMLAGLLGWQATQASKVVTVTKEVDGGVETVLPMIITTDLRLNEPRYASLPNIMKAKKKNL-QKDF-GL--DRLKTLKVVEPPARQGGGKVEDVGGLVSKLK-E Galma1 NILVPVKRSVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKAITIGPPK--SIETLRTALAMGADSAIHVEEPLAVAKTLRAIDLVILGKQAIDDDLGVTGQMLAGLLGWQATFASKLAFVVREIDGGGEELLPLVVTTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GV--DQLETLKVAEPPKRVGGGKVANVDELIAKLK-E Ganpr1 KVLVPIKRVIDYTVKIRVVKHAMNPFDEIAIEAAVQLKEVIAVSVGGAK--SVETLRTALAMGADKAVHVEQPLEVAKLLRAVQVVILGKQAIDDDSAQTGQMLAGLLGWQATFASKILKVTREIDGGLETVVPAVLTTDLRLNTPRFATLPNIMKAKKKPL-AKDL-GV--DRLEILEVAEPPKRSGGRKVESVDDLIDKLKNE Gloin1 ----GCKRVIDFAVKVRVIKHSLNPFDEIAVEEALRLREVIALTCGPPK--AQEQLRTALAMGADRAIHVEQPLAVAKLFKAISLVIFGKQAIDDDASQTGQMLAGLLNWQATFASKVLTVTREVDGGLETILPAVVTTDLRLNEPRFATLPNIMKAKKKPL-VKQL-SV--DRLETISVVEPPARQGGSKVGTVDELISKLK-E Hisca1 RILVPVKRVIDFAIKPRIVKHSLNPFDELSIEEAVRLREILAISAGGPK--CVDTLRTAMAMGADRSIHVDEPLTVAKLLKNVNLVLLGKQAIDGDQGQTGQMLAGLLGWQATQASKVVEVTREVDGGVETLLPMVITTDLRLNEPRYASLPNIMKAKRKPL-EKDY-EV--ERLKTLKVTEPPARQGGGKVEDVDGMISKLK-E Klula1 RILVPVKRVVDHAIRPRVLKFSINPFDDIAVEESVKLKEIHAVSVGPLK--AQDVLRTALAKGCDSSTLVEEPLVISKVLKKINLVVLGKQAIDDDSNNTGQMLAGLLNWQATNACKVVRVTKEIDGGEEIVLPMIITTDLRLNTPRYATLPNLMKAKKKPL-EKDFEGI--NQLKLLKVEEPPVKSAGIKVSSVDELVSKLK-E Lacbi2 NILVPVKRAVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKVITIGPPK--SLDTLRTALAMGADAAVHVQEPLSVAKTFKAWDMVILGKQAIDDDLGVTGQMLAGLLGWQATFASKIALVTREIDGGSEELLPIVITTDLRLNEPRYASLPNIMKAKKKPV-ETDL-GL--DQLELLKVEEPPKRVGGGKVGSVDELLEKLK-E Lenti61 NILVPVKRTVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKVVTIGPPK--ASETLRTALAMGADSAIHIEEPLSVAKALRAVDLVIMGKQAIDDDAGQTGQMLAGLMDWQATFASKLADVTREIDGGLEEILPLVLTTDLRLNEPRYASLPNIMKAKKKPI-QKDL-EV--DRLETLKVTEPPKRVGGGKVESVDELITKLK-E Malgl1 RVLVPVKRTIDYAVKIRVVQHSMNPFDEIAVEEAVRMREITVMSAGPAK--AQDVLRTALAMGADDAIHVEEPLAVSKILRAIGMVILGKQAIDDDASQTGQMLAGLLNWQATFASKIVTVTREVDGGLAVVVPLVVTTDLRLNEPRYASLPNIMKAKKKKV-AKDL-GLEKDRLETLKVAEPPQRQGGAKVENVDELISKLK-E Mellp23 RVLVPIKRTIDYAVKIRVVKHSMNPFDEIAVEEAIRLKEITLLTITSNKKGGQEVLRTGLAMGADSGILIEEPLSVSKTIQKVDLIICGKQSIDDDSSQVGGMLSGLLNCLAQYISSIAKVSREIDGGIEELLPAVVTTDLRLNEPRYASLPNIMKAKKKSI-ITEL-GI--DRFEILKVEEPPKRKGGLKVENVDEVIHKLK-E Mnele RVLVGCKRVIDYAVKIRVVKHSMNPFDENAIEEAVRMKQIVVASCGPSQ--SQETIRTALAMGADRGIHVEQPLAVAKIFSKLDLVILGKQAIDDDANQTTQLLAGMLDWQGTMASVVLTITREIDGGLEDILPAVISADLRLNEPRYATLPNIMKAKKKKI-EKNL-GV--DRLKILNVVDPPVRQAGEKVPDVSTLMEKLK-E Monbr RALVGCKRVIDYAVKIRVVKHSMNPFDELAVEEAVRMKEVVVVSCGPKG--AQDVLKTALAMGADRAIHVSEPLGVAKIFAKLDLVLLGKQAIDDDANQTAQMLSGLLDWQATFAYKILTVVREIDGGLETILPSVVSTDLRLNEPRYATLPNIMKAKKKPM-KTEL-GV--DRLELLSVAEPPARSAGIKVESVDELIDKLKNE Morel2 RILVATKRVVDYAVKIRVVKHSMNPFDEIGTEQAIQIKEVVVVSCGPAK--AQETLRTALAMGADRAIHVDQPLAVAKLLKAVDMVILGKQAIDDDSNQTGQMLAGLLNWQATFASKVMTVTREVDGGVETILPAILTTDLRLNVPRYASLPNIMKAKKKPL-AKDL-GV--DRLQTLKIAEPPKRQGGKLVESVDDLVDKLKNE Mucci2 RIFVPVKRVVDYAVKVRVVKHSMNPFDEIAVEEAVRIKEVVAISCGTAK--AQETLRTALAMGADRAVHVEQPLAVAKLLKAYDLFILGKQAIDDDANQTGQMLAGLLNWQTTFASKVLKVVREIDGGLETVLPAIVTTDLRLNEPRYASLPNIMKAKKKPL-VKDL-GI--DRIETLKVEEPPKRVGGRKVESVDELVDKLRNE Mydma KVLVGCKRVIDYAVKIRVVKHSMNPFDEIAVEEAIRLKEIIAISCGPAK--NEETLRTALAMGMDRGIHVVQPLAVAKLIAKVDLIILGKQAIDDDCNQTGQLLSAIMNVQATCTSKLLKVSREVDGGLENLLPCVVTADLRLNEPRFATLPNIMKAKKKKI-DVDL-AV--DHIETVSVVDPPVRSAGIKVEDVDTLIKKLK-E Neucr2 RILVPVKRVIDYAVKPRVVKHSMNPFDELSVEESVRIREICVISAGPTK--AQDVLRTAMAMGADRAIHVEEPLGVAKLLKAANLVILGKQSIDDDAGQTGQMLAGLLGWQATQASKIVQVTREVDGGVETLLPMVITTDLRLNEPRYASLPNIMKAKKKPL-EKDY-GI--TRLKTIKVTEPPPRQGGGKVEDVDGLVSKLK-E Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RILVPVKRVIDYAIKPRIVKHSLNPFDELSIEEAVRLREILALSAGGPK--CPDVLRTAMAMGADRAFHIDEPLTIAKMLQAVNLVLLGKQAIDGDQGQTGQMLAGLLGWQATQASKVVEITHEVDGGVETLLPMVITTDLRLNEPRYASLPNIMKAKKKPL-EKDL-GV--ERLKTLKVTEPPPRKGGGKVEDVDGLVSKLK-E Phybl2 RIYVPVKRVIDYAVKVRVVKHSMNPFDEIAIEEAVRMKEVVAISCGTTK--SQETLRTALAMGADRAVHVEQPLAVAKLLQAYDLFILGKQAIDDDASQTGQMLAGLLNWQTTFASKVLKVTREIDGGLETVLPAVITTDLRLNEPRYASLPNIMKAKKKPL-VKDL-GI--DRILTLKVEEPAKRVGGRKVDSVDDLIDKLKNE Picst3 RILVPVKRVIDFAIKPRIVKFSINPFCDIALEESVRIKEIHVVSVGPAK--AQDVLRTALAKGADNSTLIDEPLTVAKLLQKVNLVILGKQAIDDDANQTGQMLAGLLNWQATNASKIVTVTREIDGGADTLLPLVITTDLRLNEPRYASLPNIMKAKKKPL-DKDL-NI--DRLETLKVVEPPVREAGIKVETVDELVAKLK-D Plicr1 NILVPVKRAVDYAVKIRVVKHSMNPFDEIAVEEAVRIREIKVVTIGPAK--SAETLRTALAMGADSGIHVEEPLGVAKALRAVDLVILGKQAIDDDAGQTGQMLSGLLGWQATFASKVARVTREIDGGLEELLPLVVTTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GI--DRLETLKVAEPPKRVGGGKVDSVDELVAKLK-E Polpo KVLVPVKRVIDYAVKIRVVKMSVNPFDEIAVEEAIRMKEVVAVSLGPKT--VQETIRNSIAMGADKGIHIEQPLGVAKVLKKLNLIILGKQAIDDDANQTAQMLAGLLNWQATFASKIVKVTREIDGGLETLMPAIISCDLRLNEPRYAKLQNIMKSKKAEL-KVDL-GV--DKIKTISVEEPAKRSGGIKVDSVDQIVQNLKKH Pucgr2 RVLVPIKRTIDYAVKIRVVKHSMNPFDEIAVEEAIRLREITLLTVTSQKKGGQEVLRTGLAMGADEGILVEEPLSVSKTIKAVDLIICGKQAIDDDCSQVGGMLSGLLDCLAQFISQVIKIEREIDGGIEKLLPAVLTTDLRLNEPRYASLPNIMKAKKKPI-TTQL-GI--NMLKVLKVEEPPARKGGQKVDDVDAMVAKLK-E Punst1 NILVPVKRTVDYAVKIRVVKHSMNPFDEIAVEEAVRQREIKVVTIGPPK--AADTLRTALAMGADSAIHIEEPLGVAKALRAVDVVIMGKQAIDDDAGQTGQMLAGLMDWQATFASKLASVTREIDGGLQELLPLVVTTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GV--DRLETIKVTEPPQRKGGTKVESVDALVAKLK-E Rhior3 RIFVPVKRVVDYAVKVRVVKHSMNPFDEIAVEEAVRIKEVVAISCGTAK--SQETLRTALAMGADRAVHVEQPLAVAKLLKAYDLFILGKQAIDDDASQTGQMLAGLLKWQTTFASKILKVVREIDGGLETVLPAIITTDLRLNEPRYASLPNIMKAKKKPL-VKDL-NV--DRLQTLKVVEPPKRSGGRKVESVDELVDKLRNE Rhoto1 KLLVPVKRTVDYAVKIRVVKHSMNPFDEIAVEEAVRLREITVVSIGPAK--ASEVLRTALAMGADDAIHVEEPLAVAKALKELDLVIMGKQAIDDDSSQVGGMLAGMLGWQANFASKVVTVSREIDGGLETLLPAIVTTDLRLNQPRYASLPNIMKAKKKPM-KKDV-KA--DRLETVDVKAPPPRQGGAKVESVDEVVAKLK-E Rozal11 KILVGCKRVIDYAVRIRVVKHSMNPFDELAVEEAVKMKEVIAVSCGSIK--VQEVLRTALAMGADKAVHVDQPLDVAKLFKGIDLVILGKQAIDDDSNQTGQMLSGLMNWQATFAYKILQVKREIDGGLETVLPAVITTDLRLNTPRYATLPNIMKAKKKII-EKDL-NV--TRLQTLKVEEPPKRQSGKKVANVDELIEKLKNE Sacce1 RILVPVKRVVDFQIKPRVIKFSINPFDDIAVEEAIRIKETHAVSIGSAK--AQDILRNCLAKGIDTCSLIDEPLAIAKILKAVNLVLMGKQAIDDDCNNTGQMLAGLLNWQATNAAKVVQVTREIDDGEEVILPMVITTDLRLNTPRYVGLPKLMKAKKKPI-EKDFPEI--NQLKIVSMEEPKTKSPGVKLNSVDELIEKLK-E Salro RALVGCKRVIDYLVKVRVVKHSMNNFDEIAVEEAIRLKEVVVVSCGPKQ--SVDVIRTALAMGADRGIHVTEPLAVAKIFAKLDLVIMGKQAIDDDSNQTAQMLAALVDWQATFASKVLEVTREIDGGLETIVPAVISADLRLNEPRYATLPNIMKAKKKKV-DTDL-GV--DQLEYVSVAEPPKRSGGTKVESVDELLDKLKNE Schco3 NILVPVKRAVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKVITIGPPK--SVETLRTALAMGADSAIHIEEPLGVAKALRAVDLVILGKQAIDDDAGQTGQMLAGLLDWQATFISKLALVTREIDGGGEELLPLVVTTDLRLNEPRYASLPNIMKAKKKPV-EKDL-GV--DALETLKVTEPPKRVGGGKVANVDELVQKLK-D Schpo1 RILVGVKRTLDYMLKPRIQKMSINPFCDIAVEEAIRMKETLVVTAGQTS--SEPILRQCLAKGIGRAALINEPLSVAKLLKATNLVLLGKQAIDDDAHQTGGMLAAMLGWQFTSASKVVIVTREIDGGEETLLPAIITTDLRLNVPRFANLAKVMKARKAPL-GKDL-GV--TRLQTVSVSEPVQKRQNIMVKSVDEMVKTLK-E Sorma RILVPVKRVIDYAVKPRVVKHSMNPFDELSVEESVRIREICVISAGPTK--AQDILRTAMAMGADRAIHVEEPLGVAKLLKAANLVILGKQSIDDDAGQTGQMLAGLLGWQATQASKVVQVTREVDGGVETLLPMVITTDLRLNEPRYASLPNIMKAKKKPL-EKDF-GI--TRLKTIKVTEPPPRQGGGKVEDVDGLVSKLK-E Sphar KVLVGVKRVVDYAVKIRVVKHSMNPFDEIAVEEALRLKQVIAVSCGPKS--SQETIRTALAMGADRGIHIDEPLVIAKIFAGLNLILTGKQAIDGDNNQTAQMTAGILGWQATYASEVTKVVREIDGGLETILPAVISADLRLNEPRYATLPNIMKAKKKKIDSSDL-GV--ERVTVLEVTEPEARKAGIMVADVDELVSKLK-E Spipu1 RVLVPVKRVVDYAVKIRVVKHSMNPFDEIAIEEAVRLKEVIALTVGPSK--SNETLRTALAMGADRGVHIELPLQVAKLIKAVELLLLGKQAIDDDSSQTGQMLAGLLGWQATFASKVLTVTREVDGGLETILPAVVTTDLRLNEPRYATLPNIMKAKKKKV-EKDL-GV--DTIETVKVIEPPKRAGGIKVESVDELLSKLKNE Sporo1 KLLVPVKRTVDYAVKIRVVKHSMNPFDEIAVEEAVRLREITVISIGPAK--ASEVLRTALAMGADDAIHVEEPLAVAQALKHFDIVLMGKQAIDDDSSQVGGMLAGMLNWQANFASKIVTVSREIDGGLETLLPAVITTDLRLNQPRYASLPNIMKAKKKPL-KKDI-EA--DRLETVNVTAPPPRKGGAKVGSVDEVVAKLK-E Stehi1 NILVPVKRCVDYAVKIRVVKHSMNPFDEIAVEEAVRLREIKVVTIGPPK--SSETLRTALAMGADSGLHIEEPLGIARTLKAVDMVIMGKQAIDDDLGQTGQMLAAL--WQATYASKVARVTTEIDGGAEKLLPVVVTTDLRLNEPRYASLPNIMKAKKKPI-EKDL-GV--DMLETLKVSEPPKRVGGGKVANVDELVAKLK-E Tapde11 RILCATKRVLDYALKPRVQKQSMNPFCEIGIEEAIRIREVLAVSAGPPK--SQDTLRTAMAMGADRGTLVEEPLTVAKILKAVNIIFLGKQSIDDDCNQTGQMLAGLLGWQATCASEVVTVTREVDGGTEVLLPIVITTDLRLNQPRFASLPNIMKAKKKPL-EKDF-GI--ERFKTLKVVEPPVRKGGDKVENVDAMVAKLK-E Thetr RVLVGVKRVIDYAVKVRVVKHSLNPFCEIAVEEAVRMKEVVAVCVGPKK--AQENIRSALAMGADRGIHIEAPLNVARILAEVSMFILGKQAIDDDSNQTGQLLGGFLGWQGTMASKIVHVTREIDGGLETLLPAVVTADLRLNKPRFAALPNIMKAKRKKI-DADF-GV--DSLQTLEVNEPPVREAGIMVGSVDELVEKLKGD Treme1 NILVPVKRSIDYAVKIRVVKHSMNPFDEIAVEEAIRLREITALSIGPAK--AADTIRTALAMGADTGIHITEPISVAHAIKKVDLVICGKQAIDDDSGSTGGMLAGMLGWQGGFASKLIQVTREIDGGLEKILPFVVTTDLRLNEPRYASLPNIMKAKKKKI-ETDL-GL--DRLETISVSEPPKRVGGGKVENVDELVGKLK-D Trire2 RILVPVKRVIDYAVKPRVVKHSMNPFDDLSVEESVRIREIVAFSAGPPK--AQEILRTALAMGADRGVHVEEPLTVAKLLKKSNLVILGKQSIDDDAGQTGQMLAGLLGWQATQASKIVTVTKEVDGGVETVLPMVITTDLRLNTPRYATLPNIMKAKKKKL-DKDF-GL--TRLKVLKVTEPPQRQGGGKVEDVDGLIGKLK-E Umbra1 RIIVPVKRVIDYAVKVRVVKHSMNPFDEIAVEEAVRIKEIIAVSCGSAK--SQETLRTALAMGADKAIHVEQPLGVAKLLKAIDLIILGKQAIDDDSNQTGQMLAGLLNWQATFASKVAKVTREVDGGLETILPAIITTDLRLNEPRYASLPNIMKAKKKPL-TKQL-KV--DRLETIKVEEPAKRQGGKKVESVDDLIDKLKNE Ustma22 RVLVPVKRTIDYAVKIRVVKFSMNPFDEIAVEEAVRLREITVVSVGPPK--TADVLRTALAMGADDAIHVEEPLGISKILNEIGLIIMGKQAIDDDASQTGQMLAGLLNWQATYASKLAQVTREIDGGLSIVLPFVVTTDLRLNEPRYASLPNIMKAKKKPF-KKDL-GLEDQRQEILKVAEPPKREGGAKVENVDELISKLK-E Walse1 NVLVPIKRCIDYAVKVRVVKHSMNPFDEIAVEEAIRLREITAITIGPQK--AQDTLRTALAMGADKAIHVQEPLQVAKTLKHFELVLMGKQAIDGDENATGQMLAGLLDCQATFASSLATVTREIDGGLETVLPMIVTTDLRLNEPRYASLPNIMKAKKKPI-ENDL-PV--DRLETIKVTEPAQRTGGQKVDSVDELVEKLK-Q Zygro1 RILVPVKRVIDYQIRPRVVKFSINPFDDIALEEALRIKEIHAISIGPSK--SQDILRNCLAKGADTSTLVDEPLAVAKILKQVNLVILGKQAIDDDNNNTGQMLAGMLNWQATNAANVIKITREVDGGEEIVLPLVITTDLRLNQPRYVGLQNLMKAKKKPM-DKDFADL--DRLKLLQVVEPEPRSPGIKVGSVDELVQNLK-D [Cluster1835.fasta_al_trimmed; alignment length = 155] Allma1 -----------------------ICSYGTGSAVRLPGPSIDKPNVYDFG-TPYATILADLVGKDLYEANGLVAMLERNRRIKTAPERWDVVLTCEERVFDAVCEELWSRTPVHVVNLEIKDNPTEAAVGGRLFVDLADLDAGLDTLLLLHCVCFH Ashgo11 LCTVCASNNNRSMESHRVLGY-DVSSYGTGSAVRLPGLSIDKPNVYPFG-TPYNDIYNDLLAQSRYKSNGLLEMLDRNRRIKKAPEKWDFVFTCEERCFDSVCEDLMNRKIVHVINLDIRDDNENAKIGGRAMLELVPFEDTIMDVVLLYSPAYY Aspfu1 FCTVCASNQNRSMEAHLRLPF-PVISFGTGSLVRLPGPSITQPNVYNFNTTSYSQMYDELLAKDLYRNNGLLNMLDRNRNLKWGPERFDVIITCEERCWDAVVDDLMNKRPVHVFNVDIRDNHEEALVGGKAILELASFDERVPEILALWTLAWL Aurde31 FCVVCASNQNRSMEGHNVLGM-RVISYGTGSAVRLPGASADRPNVYQFG-TPYNDMYEELSAKDLYQANGVLAMLDRNRRIKRAPERWDIVITCEERCFDAVCDDLLSRRPVHVINIEIKDNHEEAHIAGKAILDLADMDEDMGKILLLHVVTYY Batde5 FAVVCASNQNRSMEAHHVLNF-SISSYGTGTAVRLPGPSADKPNIYSFG-TPYDDIYNELASQDLYTQNGLLLMLDRNRRIKRAPERFDVIFTCEERCFDAACEGILNRQPVHVINVEIIDNHEQATVGGKLILQLADLDQEIGALLILYTITYL Botbo1 FGVVCASNQNRSMEAHNVLGY-RVVSYGTGSTVRLPGPSIDKPNVYQFG-HPYEDMYQDLKAQDLYTANGLLQMLDRNRRLKRAPERWDVVITCEERCFDAVCDDLLTRRTLHLINVEIKDNHEEALIAGRAILDLADIDESMQDILLLHTVAYI Botci1 FCTVCASNNNRSMESHLRLHY-PVISFGTGSLVRLPGPSITQPNVYQFNKTSYDSMYKELESKDLYRANGILNMLGRNRSVKWGPERWDIVITCEERCWDAVVDDLLNRRPVHVINVDIKDNHEEALVGGRGILDLAGFDERVPEIIAVWTLAWF Caeel FAVSCSSNMNRSMEAHGILGF-NIESYGSGNQVKMPGPTVDKPNCYEFGPTTYEDIYADLTNKDLYTQNGLLHMVDRNRRIKSRPQRFDIVLCLEERVFDQVVDFLNRSNPVHVINIDIEDNAEEATFGAFFVADLCDFEEDIDQIILLHTICFY Canalb1 ICTVCASNNNRSMESHKQLGY-DVHSFGTGTAVRLPGPSVDKPNVYEFG-TPYQVMYDDLISQKLYESNGLIHMLERNKSVKEAPEKWDLVITCEERCFDSVIDDLMHRRLVHVINIDIKDDNENAIIGGKGILKLVILEDQMMSIITLYSVSYY Cangl FCTVCASNNNRSMESHRILGY-EVSSYGTGSAVRLPGLSFDKPNVYPFG-TPYNDIYNDLLSQSRYKANGLLQMLDRNRRLKKAPEKWDFVFTCEERCFDAVCEDLMNRKIVHVINIDIRDDNENAKIGGRAILELALFEDCILDILCLYAPSYY Capow YAVICSSNQNRSMEAHALLGF-DVCSYGSGNNVKLPGPTPDQPNVYEFN-TPYNDIYAELASKDFYTGNGILSMLDRNRKIKTAPERFDVIITCEERVFDQVLEVLEARRPVHIINIDIKDNHEEATVGAALIFKMCDLEVKIEEVLLLHSIAFY Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin FAVVCSSNMNRSMEAHRCMGY-AVESFGSGNQVKLPGSSADRPNVYSFS-TKYDDILTDLKQKDLYTQNGVLNMLDRNRRIKDRPQRFDVIITLEERVYDQIMEDFNTREAVHVINLDIQDNHEEATIGAFVVCELSDLDNDIDELLIIHSVHFY CocheC53 FCTVCASNQNRSMEAHLQLHL-PTISFGTGSLVRLPGPTITQPNVYHFNSTTYRAIHDELAEQNLYTNNGLLNMLGRNLNIKGYPERFDVVITCEERCFDAVLEDLHNKRPVHVFNVDIKDNHEEALVGGKAILDLAGFDERVPDILALWSLAWF Coere1 FAVICASNMNRSMEAHYQLGY-NIESYGTGSAVRLPGPTATQPKIFHFG-TAYNKIYDELKTQDLYTRNGLLMMLDRNRDVKMAPQRFDVIFTCEERVFDAVCEELLNRKPVHVINVDIEDNHREATLGAKTIVELADIERDMDRIILLYTVAFY Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 FCVVCASNQNRSMEAHSILGY-RVISYGTGSAVRLPGPSIDKPNIYSFG-TPYNTIYEELHGKDLYTANGLLHMLDRNRKIKLAPERWDIVITCEERCFDAVCDDLLARRVVHIINIEIKDNHEEAFIAGKAILDLADVDEDINHILILHAVAFY Copci FCVVCASNQNRSMEGHNVLGY-RVISSGTGSAVRLPGPAIDKPNIYSFG-TPYNTIYEELSSKDLYTANGLLQMLDRNRRIKTAPERWDVVITCEERCFDAVCDDLLNRKPVHIINMEIKDNHEEAAIAGKAMLDLADIDENIDKILLLHAVAYY Croqu1 FCVVCASNQNRSMEGHNVLAF-RVTSAGTGSMVRLPGPAIDKPNVYPFG-TPYDDMYQDLKNKDLYMANGILPMLDRNRRLKRAPERWDIIITCEERCFDAVCDDLFNRKPVHLINVEIKDNHEEALLAGKALLELCDLDGELEGILLIHTVAYY CryneH991 FCV------NRSMEAHYVLSF-RVVSAGTGSAVRLPGPAIDKPNVYRFG-TPYDDIYRDLESQDLYTRNGILPMLDRNRKVKKAPEKWDVVITCEERCYDAVCDDLLTRRPIHIINIEIKDNPEEAHIAGQSILELAD----------------- Crypa2 FCTVCASNQNRSMEGHLRLGF-PVISFGTGSLVRLPGPTITQPNTYHFDKTSYDSMYRELEAKDLYRANGLLNMLDRNRGIKWGPERWDVVITCEERCWDGVVEDLLARRPVHVINVDIKDNHEEAAVGGRGIVDLAGFDEKVPDVLATWTLSWF Debha1 ICTVCAANNNRSMESHKQLGY-NVRSFGTGSAVRLPGPLVDKPNVYEFG-TPYDDIYRDLTSQEMYESNGLIRMINRNRHIKRAPEKWDLVITCEERCFDLVLDDLMVRQAVHIINIDIKDDYENAVIGGKGILKLVILEDQMMKLLTLYSVAYY Dekbr2 ------------MEAHKVLGY-LVRSYGTGSAVRLPGPSIDRPNVFSFG-TPYTKIMEVLNSQDMHKSNGVLDMTKRNIKVKKAPERWQVVITCEERCFDSVVDDYLTRSIVYCFNVDIRDDHESARAGGRAILDLAPFEDRIPDLILLHALCYH Dicdi IAMVCASNQNRSLEAHHLFGFKNIRSFGTSAHCKLPGPSIHQPNIFSFG-TPYQEIYTSLKNQDLYIRNGLLNMLERNISVKLAPEKWEIVYTFDQRVYDAVIEDLLQRQPVHIINLQVKDTHEEAVGGAQHALEITNWEEKLDQILFLHTLMFY Dmel VAVVCSSNMNRSMEAHNFLGF-NVRSYGTGERVKLPGMAFDKPNVYEFG-TKYEDIYRDLESKDFYTQNGLLHMLDRNRRIKKCPERFDIIVTVEERVYDLVVMHMESMRPVHVLNVDVVDNAEDALMGAFVITDMIDLDNDIDELIILHSVLFY Enthi IAVICRSNQNRSISAHCRLGY-NVSSFGTGVYTILPGAT--RNFGFQFG-IPYKDIKNSLPKDEYYRKNKIYQMLDRNANLKSAPEKFNIIITLDYSVFMDVLEYFDSRSLCYVFNLTVMDQLDTAEKGAIEVSEFLDWMNNIDHVIVLHSMQMY Falba VAVICASNQNRSMEAHDVLGI-PVHSYGTGSRVKLPGPSADKPNVYPFG-TPYASIEKELGSKDLYKGNGLLPMLERNSRVKRAPERFDVLITCEARCFEAVRATLTSIVPVHVINVEIKDNRTEARLGAADILNLVDLDAVIPAVLVLHTICYY Fomme1 FCIVCASNNNRSMEGHSVLGF-HVVSSGTGSAVRLPGPSIDKPNIYAFG-TPYNTMYEELNSKDLYTVNGILNMIDRNRKIKLAPERWDVVITCEERCYDAVCDDLLSKRPVHVINIEIKDNHEEALIAGKAMLDLADLDEDIGKILLLHTVAFY Fusgr1 FCTVCASNNNRSMEAHLRLDY-PVISFGTGSLVRLPGPTITQPNVYHFNKTSYDSMFKELESKDLYKNNGILNMLNRNRGVKWGPERWDIVITCEERCWDAVVDDLMNRRPVHVINVEIKDNHEEAAVGGQGILDLATFDERVPDILATWTVAWF Galma1 ------------MEGHHVLGY-RVISYGTGSAVRLPGPSIDKPNIYPFG-TPYNAIFEELSAKDLYTANGLLPMLDRNRNIKLAPERWDVVITCEERCFDAVCDDLLTRKPVHIINIEIKDNHEEALIAGKAMVDLADIDENIDKILLLHAVAFY Ganpr1 YAVICASNQNRSMEAHNVLGR-DVHSYGTGTAVRLPGPAVDKPNVYPFG-TPYDDIYHDLEGKDLYTSNGLLHMLDRNRRIKRAPERFDVIVTCEERCFDAVCEDLTTRRPVHVVNVEIRDNHEDAAVGARQIQRLTDVDADIDSIVVMHAVHYY Gloin1 FAVVCASNQNRSMEAHHVLGF-KVKSYGTGSAVRLPGPSLDRPNIYPFG-TPYDYMFKDLHEKDLYKQNGLLDMLDRNRKIKLAPEQWDVIITCEERCFDAICEDLTDRRPVHIINIDIKDNHEDAMLGGRAILQLADLDEAIPGILILHSIAYF Hisca1 FCTVCAANQNRSMEAHNRLSY-PVISFGTGSLVRLPGPSIAQPNVYNFNTVSYAQMYDELLQKDLYRNNGVLPMLERNKSVKWGPERFDAIITCEERCWDAVVDDLMNRRPVHVFNVDIRDNHEEALVGSKAILDLACFDDQVPEILALWTLSWF Klula1 FCTVCASNNNRSMESHRVLGY-DVSSYGTGSAVRLPGLSIDKPNVYSFG-TPYDDIYNDLISQSRYKQNGVLEMLDRNRKLKKAPEKWDFVFTCEERCFDSVCEDLMNRLIAHIINIDIKDDNENAKIGGRAILRLAQFEDFIMDVFLTYSAAYY Lacbi2 FCVVCASNQNRSMEGHHVLGY-QVISSGTGSAVRLPGPSIDKPNIYPFG-TPYNTIYEELNSKDLYTANGLLPMLDRNRRLKLAPERWDIVVTCEERCFDAVCDDLLTRKPVHVINMEIKDNHEEALIAGKAMLDLA------------------ Lenti61 FCVVCASNQNRSMEGHYVLGF-RVCSSGTGSAVRLPGPAIDKPNIYAFG-TPYNDIYEELQAQDLYTANGLLQMLDRNRRIKLAPERWDIVITCEERCFDAVCDDLLTRKPVHIINIEIKDNHEEAHIAGKAIVDLADIDEEINGILILHAVAYY Malgl1 ------------MSAHAALGY-LVTSCGTGSAVRLPGPSIDKPNIYAFG-TPYETMFQDLMKKDLYEANGLLPMLDRNRHIKSAPERWDVVITCEERCFDSVCEDLLSRRPVHVINVEIKDNHEEAQKAANAILSLADIDEDMDEILLLHTVAYY Mellp23 FCVVCASNQNRSMEGHNVLAF-RVTSAGTGSMVRLPGPAIDKPNVYPFG-TPYDDMYQDLKNKDLYTANGILSMLDRNRRIKRSPERWDIIITCEERCFDSVCDDLFYRKPVHLINLEIKDNHEEAFLAGQALVDLCDLDGQLHLVLLIHTVAYY Mnele IAVVCSSNQNRSMEAHNLLGY-RVQSFGTGSCVKLPGVTVDKPNIYSFD-TPYQDQFVDLKRKDFYTQNGLLNMLDRNRRIKQKPERFDLIVTCQERVFDQVLENLSERKMVHVINVEIRDNHDDATLGAFIIHELVDHEAELEEIIFLYSPSFY Monbr YAVVCSSNQNRSMETHLVFGF-NIESYGTGSAVKLPGPSIDKPNVFGFDDTTYEDMYKQLKEQNLYSGNGVLDMLERNMAIKPRPEKFDIILTCESRIFDEVLRDLEERTPVHIINLDIPDNHSAATVGALNLYKLADLDDDIDDIILLHALAFY Morel2 FAVICASNQNRSMEAHNVLGF-TVSSYGTGTMVRLPGPTIDKPNIYNFG-TPYNEVYQELKGKDLYQSNGLLLMLDRNRKIKNSPERWDVIITCEERCFDAVCEDLIQRNPVHVINVDIKDNYEEAMVGGRMILHLADLDQEIQPILVLHSVSYF Mucci2 YAVICASNQNRSMEAHHVLGF-NVRSYGTGTMVRLPGPAIDKPNIYPFG-TPYEQVYQELKKQDLYTQNGLLSMLDRNRKTKEAPQRWDVIITCEERCFDSVVEDLSNRQSTHVINVEIKDNHEDALLGGRAILQLADIDADMDGIIILHTVAYF Mydma IAVTCSSNQNRSMEAHGVLGF-NVRSYGSGSYVKLPGPTADKPNIYHFN-TPYDQMYQDLARKDLYKQNGILHMLDRNRRIKRSPERFDIIITAEEKVYDQVLEEFNRRRPVHIINIEIADNHEEATLGAFQICELCDLDDDIAEILILHTVAFY Neucr2 FCTVCASNQNRSMEGHLRLNY-PVISFGTGSLVRLPGPSITQPNVYKFNETSYDSIYRELEAKDLYRANGLLNMLGRNRQVKWGPERWDVVITCEERCWDAVIEDLLNRRPVHVINIDIKDNHEEASVGGRAIVDLAGFDERVPDVLATWTLAWF Orpsp11 FAVICASNQNRSMEAHNALGF-NVKSYGTGSAVRLPGPSIDKPNVYPFG-TPYEDIYQDLIKKDLYTQNGLLKMLDRNKKIKKAPERFDIIFTCEERCFDAVCEDLINRLPVHVINIEIKDNHEDAAVGGQLITKLADVGCNVENTLILHSLSYY Pench1 FCTVCASNNNRSMEAHLQLAF-PVISFGTGSLVRLPGPSITQPNVYSFNTTSYNQMYEELSGKDLYRSNGILNMLDRNRQLKWGPERFDIIITCEERCWDAVVDDLMNKYPVHVFNVDIKDNHEEALTGGKAILDLASFDEKVPEILALWTLAWL Phybl2 YAVICASNQNRSMEAHNVLGF-DVASYGTGTMVRLPGPSIDKPNIYPFG-TPYDQVYQELEGKDLYTQNGLLTMLDRNRKVKDAPQRWDVIITCEERCFDAVVEDLSNRKSTHVMNVEIKDNHEDATLGGRAILQLADIDADVDDIIILHTVAYF Picst3 ICTVCASNNNRSMEAHKQLGY-DVKSFGTGSAVRLPGPSIDKPNVYEFG-TPYEDIYNDLISQNMYEANGLIHMLDRNRHVKPAPEKWDLVITCEERCFDSVMDDLMFRQIVHVINVDIKDDNENALLGGKGILKLVILEDQMMSILTLYGISYY Plicr1 FCVVCASNQNRSMEGHFVLGF-RVISYGTGSAVRLPGPSIDKPNIYQFG-TPYNQIFEELSGKDLYSANGLLQMLDRNRRIKLAPERWDIVITCEERCFDAVCDDLLTRRPVHVINLEIKDNHEEALIAGKAMVDLCDIDEDIDKILILHAVAFY Polpo LAMVCASNQNRSVEAHNLFGYRNIRSFGTSGNCKLPGPSQDRPNIFPFG-TPYQSIHESLRQQNLYTQNGILNMLERNQRVKLAPEKWDIVFTFDQRVFDMVVDDLTQRQPVHIVNLQVKDTHEEAAGGASHALQLLNWEDSMDDILLLYTLMFY Pucgr2 FCVVCASNQNRSMEGHNVLAF-RVTSAGTGSMVRLPGPAIDKPNVYSFG-TPYDDMYQDLKEKDLYTANGILSMLDRNRKLKLAPERWDVVITCEERCFDAVCDDLFSRKPVHLINIEIKDNHEEASLAGKALLDLCDLDSDLEEILLIHTVGYY Punst1 ------------MEGHNVLGY-RVISFGTGSAVRLPGPSIDKPNVYPFG-TPYNTIYEELSQKDLYTANGLLQMLDRNRRIKLAPERWDIVITCEERCFDAVCDDLLSRRPVHVINIEIRDNHEEAWIAGKAMLDLADIDEDIDQILLLHAVAYY Rhior3 -------------------------------MVRLPGPSINKPNIYPFG-TPYEQVYQELKRQDLYTQNGLLNMLDRNRKTKSAPQRWDVIITCEERCFDSVVEDLANRQSTHVINVEIKDNHEDALLGGRAILQLA--------VV-------- Rhoto1 FCVVCASNQNRSMEAHNVLNF-KVISAGTGSAVRLPGPSIDRPNIYAFG-TPYEHMYQDLKQKDLYTANGLLTMLDRNRKIKTAPERWDVVITCEERCYDAVIDDLLSKRPVHVINVEIKDNHEEALIAGKAMLELCDLDSEIDDILLLHTVAYY Rozal11 ------------MEAHYVLGF-DVCSFGTGAKVKLPGPSIDRPNIYDF-GTPYTDMYEELKRQDLYVQNGVYYMLERNMKIKKAPERFDFLITCEERCYNAVVEELTKRIPVHVFNFDIPDTNEDAAIGARAIKDFADLD--IDELAILYTLSFY Sacce1 FCTVCASNNNRSMESHKVLGY-NVSSYGTGSAVRLPGLSIDKPNVYSFG-TPYNDIYNDLLSQSRYKSNGLLQMLDRNRRLKKAPEKWDFVFTCEERCFDAVCEDLMNRKIVHVINVDIKDDDENAKIGSKAILELAPFEDCIMDILSLYAPSYY Salro YAVVCSSNQNRSMEAHLFLGF-NVESYGTGSCVKIPGPSIDRPNVFEFDSISYDEMYKQLEAQNLYQQTGMLAMLDRNRKIKRNPEKFDIILTCETRIFDEVVRDLQQRELVHICNLDIKDTHECATQGALNFVHLADLDEEVEAVILMHSVAFY Schco3 LLVIHCSLQNRSMEGHFVLGY-RVCSYGTGSAVRLPGPSIDKPNIYPFG-TPYNAIYEELQAKDLYTANGLLQMLDRNRNVKLAPERWDVVITCEERCFDAVCDDLLTRRPVHVINIEITDNHEEALKAGKIMLELADLDEDMEKIVFIHVVAYY Schpo1 ISVICASNQNRSMEAHNVLGY-QVDSFGTGSAVRLPGPSIDKPNIYQFG-YPYDEIYKELEAQDLYTANGLLKMLDRNRRIKRAPCRWNIVITCEERCYDAICEDLYRRRPVYLINVDIKDNHEEASVGGKAILDLVKLEELFPSIMVLYTIHFF Sorma FCTVCASNQNRSMEGHLRLNY-PVISFGTGSLVRLPGPSITQPNVYKFNETSYDSIYRELEAKDLYRANGLLNMLGRNRQVKWGPERWDVVITCEERCWDAVIDDLLNRRPVHVINIDIKDNHEEASVGGRAIVDLAGFDERVPDVLATWTLAWF Sphar -------------------------------------------------------MYRDLEAQNLYTSNGVLMMLDRNRKCKDHPERFDIIVSCEERVFDQILQDEYEGETVHIVNLDIKDNHEDATIGSFAMNDLCDLDEDMEDII-------- Spipu1 LAVICASNQNRSMEAHNVLGY-VLSSYGTGSAVRLPGPAADKPNIYPFG-VPYNDIFNDLLKKDLYKANGLLPMLDRNRRIKRAPERFDVIISCEERCFDSACEDLDNRRPVHLVNIEIKDNHEEAAVGGQLILQLVDRDAEMDMILVLHTVSFY Sporo1 FCVVCASNQNRSMEGHNVLNF-NVVSAGTGSAVRLPGPSIDRPNIYSFG-TPYEHMYQDLKTKDLYTANGLLGMLDRNRKIKTAPERWDVVITCEERCYDAVIDDLLNRRPVHVINVEIKDNHEEALIAGKALLEL------------------- Stehi1 ------------MEGHFVLGY-NVVSYGTGSAVRLPGPSIDKPNIYSFG-TPYNDIFEELNAKDLYSANGVLQMIDRNRRVKLAPERWDIVITCEERCFDAVCDDLMSRRPVHIINVEIKDNHEEALIAGKAMLDLADIDEDIDKILLLHAIAYY Tapde11 IATVCASNNNRSMQAHKVLGF-AVSSYGTGSAVRLPGPSIDRPNNYSFG-TPYNTIYEELKKQDLYTANGLLTMIDRNRKIKNAPERWDIVITCEERCFDAVCEDLLNRRMVHVINVDIKDNAEEAAKGGQGILKLVTLDDQIIDVIVLHAVQFY Thetr YTMVCASNMNRSMEAHYVLGF-NVSSFGTGSQIKIPGPSRDKPNCYEYGTATYKDVYEDLLSKDLYRRNGMLAMLERNIDTKTMPEKWDVVVCFENRVFEAVLTDLLERDPVQVINIETVDNSEAATLGGQVTLKLIDLEDDLESVLILHTTAFY Treme1 -------------------SF-RVISAGTGSAVRLPGPAIDKPNVYRFG-TPYDVIYRDLDSKDLYTRNGLLPMLDRNRKVKTAPEKWDVVITCEERCFDAVCDDLYARRPIHVINVEIKDNPEEALIAGQSILELADLDEEIDTILLSHTVAFF Trire2 FCTVCASNQNRSMEAHLRLNY-PVISFGTGSLVRLPGPTITQPNVYQFNKTSYDSMYKELEAKDLYRNNGILNMLGRNRGVKWGPERWDVVFTCEERCWDAVIDDLLNRRPVHVINVDIKDNHEEAHIGGQGILDLASFDERVPEIISTWTLAWF Umbra1 YAVICASNQNRSMEAHNVLGF-NVHSYGTGTMVRLPGPAIDKPNIYPFG-TPYDSVYQELKGKDLYTQNGLLSMLDRNRKIKDAPQRWDVIITCEERCFDSVFEDLANRKSTHLINVDIKDNHEDALLGGRAILQLADIDNDIQTIIILHTIAYY Ustma22 FCVVCASNQNRSMAAHALLGF-NVTSAGTGSAVRLPGPKINLPNIYPFG-TAYTDIISDLNSKDLYWANGLMTMLNRNKDVKRAPERWDVVITCEERCFDTVCEDLFSRRPVHVINVEIKDNHEEAVAAGKAILDLADLDEEIEPILILHTVAYY Walse1 FCVVCSSNQNRSMEAHKVLKF-NVTSFGTGTAVRLPGTSIDRPNTYSFG-TPYNHILQDLESKDMYTNNGLLAMLNRNRQIKLAPERWDVVITCEERCWEAVCDDLLNRRSVHIINIEIKDNQEEAAIAGKAILDLADLDQDIESILLLHCVAYY Zygro1 FCTVCASNNNRSMESHKVLGY-SVSSYGTGSAVRLPGLSIDKPNVYQFG-TPYNDIYNDLLFQSRYKSNGLLQMLDRNRKLKKAPEKWDVVFTCEERCFDAVCEDLMGRKIVHVINVDIKDDNENAKIGGLAILKLAPFEDCMMDILVLYSPAYY [Cluster1837.fasta_al_trimmed; alignment length = 196] Allma1 AMKKKKK--GD------------SERAAEAWLGS-D--RDYTYDELLGRVFRILNPALAG--GRKRYTMVPPQIAREGSKKTAFMNIADICNRMRRNYDHVVAFIYSELGTSGSVDGSQRLIIKGRFQPKQIENVLRRYIVEYVTCKTCKSPDTILRK--ENRLHFMQCESCGSTRSVSAITSGFKAQT--G--SR Ashgo11 SLKKKKKLFAG-LKKKKK--KAKKELEK-------DV--GLPYSDLLSRFFKILNPELAGDRSGPKFRIPPPVCQRDG-KKTIFANIQEISEKLQRSPEHLIQYLFAELGTSGSIDGQKRLVIKGKFLSKQMENVLRRYIMEYVTCKTCKSINTELKKEQSNRLFFLVCKSCGSTRSVSSIKTGFQATV-----KR Aspfu1 -------LFKG-LKKKK---TKKAKLAEGIWAHDAT--QAIPYSLLVSRFFSLIHPDLLSS-GTKSYKIPPPQCLREGNRRTIFANIADICKRMKRSDDHVMQFLFAELGTSGSVDGSRRLVIKGRFQQKQIENVLRRYIVEYVTCKTCRSPDTELNK-GENRLYFVTCNSCGSRRSVAAIKTGFRGQV--G--RR Aurde31 SLKKKKKMFGD-LKKKKK---KKKQLKAEPWLGS-D--RDYTYQELLNRFFSALNPALLSSAG-KRYTIAPPSIHRDGNKKTVFANIADICKRMHRQPEHVIQFLFAEMGTTGSVDGAGRLVIRGRFLQKQVENVLRRYIVEYVTCKTCKSPDTILTK--ENRIYFMSCESCGSRRSVSAIKSGFQAQV--G--RR Batde5 -----------------------ALLKDEAWLSS-N--RDYTYNELLTRVFNIINPERAQG-GTVKYNIVAPQILKEGSKKTSFANLVDFCRRMRRTPDHLVQFLFAELGTSGSIDGNQRLIIKGKFQQKQIENVLKRYIVEYVTCKTCKSAETVLTK--ENRLFFLQCESCGSSRSVSAIKTGFVAQT--A--RR Botbo1 SLKKKKRMFGD-LKKKKK---KKKQLGDDAWLGS-D--RDYTYSELLGRIFRTLNPDLSSA-SRKRYTIVPPSVHREGNKKSIFANVADICKRMRRPSEHVIQFLFAELGTTGSVDGEKRLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTLLDK--ENRIYFVSCESCGSRRSVSAIKTGFQAQV--G--KR Botci1 -------------KKKKK--SKKARLAAGIWAHDET--KVISYEQLLSRFFTLLNPDHASS-GSKSYKIPPPQCLREGNKKTIFANIAEICKRMKRTDEHVTQYLFAELGTNGSVDGSRRLVIKGRFQQKQIENVLRKYIMEYVTCKTCRSPDTELNK-GENRLFFITCNSCGSRRSVTAIKTGFSAQV--G--KR Caeel G-KKKKS----------------KT---GAW-------PDYTYEEALTLVYQVMNPDFA-G-DKKKFAIKLPEVARAGSKKTAFSNFLEICRLMKRQDKHVLQFLLAELGTTGSIDGSNCLIVKGRWQQKQFESVLRKYIKEYVMCHTCKSPETQLTK--DTRLFFLQCTNCGSRCSVTAIKSGFKAVV--G--KR Canalb1 SLKKKKKLFSG-LKKKKKSSSKKQQLEE-------AI--GLSYPDLLSRFFDILNPELAGDRSGPKFRIPPPIVQREGSKKTLFANVQEIATVLQRSPEHLIQYLFAELGTTGSIDGEKRLILKGKFQPKQMESVLRRYIIEYVTCKTCKSMNTELKRESANRLHFLSCKACGSTRSVSSIKTGFQAQI--G--KR Cangl ------EPFAG-LKKKKK--KSKKELAK-------NV--GLPYPELLSRFFNILNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIEEISEKLQRSTEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKKEQSNRLFFMVCKSCGSTRSVSSIKTGFQATV--G--KR Capow SLKKKKK---E-IKKKKK--KSKAE---ETWLGS-D--RDYTYPELLQRVFDIMNPTVAVG-EKRRFVMKPPQVLRIGAKKCALVNFVEICSLMRRTQDHVLLFILSELGTTGSMDGNNHLIVKGRFQQKQMETVLRHYIREYVTCHTCKSPETNLTK--ENRLSFLQCETCGSTCSVAAIKAGFQAIT--T--KR Catan2 AMKKKKK---D------------SKRAPETWIGT-D--RDYTYDEILSRVFRILNPALAG--GRKRYTIVPPQVAREGSKKTVFANIDDICNRMRRNYDHVVQFLYAELGTSGSVDGSKRLIIKGRFQPKQIENVLRRYIVEYVTCKTCKSPETILRK--ENRLYFQQCESCGSTRSVSAIQGGFKAQV--G--SR Cioin DLNKKKK-----MKKKKK--KKTEELVLKTWSGS-D--RDYTYDELLTHVFEIMNPEMIAG-EKKRFIMKPPQCARVGTKKTSFLNFAEICQTLRRQPKHILAFILAELGTSGSVDGNNQLIIKGRFQQKQLESVLRRYI-------------------------------------------------------- CocheC53 VPERK-TMFAD-LKKKKK--STKAKLAAGIWQHDQT--TPISYNLLLNRFFTLLHPDLASS-GTKSYKIPPPQCMREGNKKTVFANLAEICKRMKRSDEHVAQFLFAELGTSGSFADQKRLVIKGRFQQKQLENVLRRYIVEYVTCKTCRSPDTDLSK-GENRLNFVTCNSCGSRRSVQAIKTGFSAQI--G--KR Coere1 DISQKLKIFLSALKKKKK---PKAEL--EPWIGT-D--RDYTYPELLGRFYKILNLESTG--EKRRYTIVPPIIAPDGSKRTLFANIEDISRRMHRSPDHVIRYLYAELGTNGSVDQEQRLLIKGRFKQKQIENVLRHYISEYVACKTCKSGETSLSK--ENSLSFIKCESCGSTRTVAAIKTGFQAATK-D--KR Conco1 --MKKKKMFSD----------KKVEEEEEGWLDS-D--RDYTYNELLNRFFRVLNPQLIG--EKRRFAVPPPEMARDGPKKTIFVNFADICNRLKRSPENVIQFLYAELGTTGSVDGNSRLIIKGRFQQKQIQNILRRYIAEYVLCKTCKSPNTKLNK--DNRLIFMQCESCGSTRSVTTIKGGYQATT--N--RR Conpu1 SLKKR-KMFPEGLKKKKK---KKKELNDEPWLSS-D--RDYTYPELLQRFYASLNPALLMSTG-KRYTIAPPQILREGNKRSIFANVADICKRMHRQPEHVIQFMFAEMGTTGSVDGSGRLVIKGRFQPKQIENVLRRYIVEYVTCKTCKSPDTLLTK--ENRIFFMSCESCGSRRSVNAIKSGFQAQV--G--KR Copci SLKKK-KMFGD-IKKKKK---KKKELNEEAWLGT-D--RDYTYQELLTRFYNSLNPALLSSTTRKRYTIAPPQLFREGNKKSIFANVTEICKKMHRQPEHVIQFLFAEMGTTGSVDGAGRLVIRGRFQQKQIENVLRRYLVEYVTCKTCKSPDTLLTK--ENRIFFVACESCGSRRSVNAIKSGFQAQV--G--KR Croqu1 NLKKKKK-FSD-LKRKKK---KKRELAEKAWLKETD--RDYTYDELLGRFYQSLHPSLSIGGTKKRYTLAPPSVHREGNKRSIWANVNEICKKMHRGHEHVIQFLFAELGTSGSVDGNGNLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTLLQK--DNRLYFVACESCGSKRSVSAIKTGFSAQI--G--KR CryneH991 -MKKKKKLFAD-LKKKKK--KKKKELEDEAWVVE-N--REPTYPELLKRFFNLLNPELAG--EKRRYTIVPPQVAREGTKKTLFANITDICRRMRRQPEHVIQFLYSELGTTGSVDGAQRLVMKGRYTQKQIENVLRKYIVEYVTCKICKSPDTILDK--ENRLYFMTCESCGSRRSVSAIKTGFQAQI--G--KR Crypa2 DRSTK-PDGLD-LKKKKK--VKKAKLAAGVWNHDDK--TPITYNLLLSRFFTLLNPEHATG-ISKSYKIPPPQCVREGNKKTIFANLAEICKRMKRSDEHVTAFLFAELGTSGSTDGSRRLVIKGRFQPKQLETVLRKYIIEYVSCKTCRSPDTELSK-GENRLSFVTCNSCGSRRSVAPIKTGFSAQI--G--KR Debha1 SLKKKKKMFAG-LKKKKK--SKKQQLEQ-------AV-GGLQYEDLLSRFFSILNPELAGDKSGPKFRIPPPVCQREGSKKTLFANVQEIATVLQRNPEHLIQFLFAELGTSGSIDGEKRLVLKGKFQPKQMESVLRRYIIEYVTCKTCKSMNTELKRESANRLHFLSCNACGSTRSVSSIKTGFQAQI--G--RR Dekbr2 TLKKKKKLFAG-AKKKKKSKAKKKALAA-------ET--FIPYSSLLDRFYTILNPEMAGGQH-HKLKIPPPEVARDGNKKTVFVNVQVIAHVLQRNPEHLIQYLFAELGTSGSIDGEKRLIIKGRFQSKNIESVLRRYIQEYVICKTCKSMNTELKRESANRLHFIVCKACGSTKSVASIKTGYQAQI--GANRR Dicdi TMKKKKK------KEKRK--KKKTEPTEIPWAGT-D--RDYKYSELTYRIYHLLNPDLISD---QKRTMKPPQVMREGTKKTIWANFAEICGTLNRKVEHVYNYVFAELGTNGSIDGNQRLVIRGRFKTSQIEIVIRHYISEYVACRNCKSPNTVLER--NNRLYFLCCNACNSKRSVAVIKKGLEG---AG--KK Dmel TLLKKKK---D-LKKKKK--KKKK----STWFGS-D--RDYTYDELLKRVFEIINPDMAAG-RKPKFVMRPPQVLRVGTKKTSFANFMDIAKTLHRLPKHLLDFLLAELGTSGSMDGNQQLIIKGRFQPKQIENVLRRYIKEYVTCHTCRSPETILQK--DTRLFFLQCESCGSRCSVASIKSGFQAVT--G--KR Enthi TTEKKVK-----VKKTKK--ALK------------NE-GLYTYDELLDRIFAQCQNS-----SKQEIELPQIKVVREGSKRVIWENFTDICKRLHRSPEDIKVFVLEELMTIGSIDAKGGFTIKAKLQPHQLENILIKYVSQFVQCPECKSLDTELIK--ENRINFIKCNACSSKCSVAV--------------KK Falba IIKKKKKPFDG-LKKKSK--KKKQALMEAVYQGN-D--TPYAYGDLLQRAFRLINPEHGG--DRKRYTMIPPQVNRDGAKKTIFANLIEICRRMRRTNEHVTNFLLAELGTSGSVDGAGRLIIRGRFSPKQIESVLRHYIMEYVTCKICKSRDTQLSK--DNRLQFIQCDACNSRRSVATIKTGFSAQV--G--RR Fomme1 SLKKKKKMFGD-LKKKKK---KKRELGEEPWLGS-D--RDYTYPELLHRFYNLLNPSLLSSAG-KRYTIPPPSVHREGNKKSIFANVNDICKRMHRPLDHVTQFMFAEMGTTGSLDGSSRLVIKGRFQQKQLENVLRRYIVEYVTCKTCRSPDTVLQK--ENRIFFVSCESCGSRRSVQTIKTGYQAQV--G--RR Fusgr1 PTERK-SGGLD-LKKKKK--SKKKQLEKGIWAHDET--KAIGYTMLLSRFFSELNPDHVMT-GTKSYKIPPPQCMREGNRKTVFANIADICKRMKRTEEHVTAYLFAELGTSGSVDGSRRLVIKGRFQQKQIENVVRKYIIEYVTCKTCKSPDTELNK-GENRLYFITCNNCASRRSVTAIKTGFSAQV--G--KR Galma1 SLKKR-KMFGD-MKKKKK---KKKEINDEAWLKS-D--RDYTYQELLTRFYASLNPSLLSSASKKRYTIAPPQLFREGNKKSIFANVTDICKKMHRQPEHVIQYLFAEMGTTGSVDGAGRLVIKGRFQQKQIENVLRRYMVEYVTCKTCKSPDTLLTK--ENRIFFMACESCGSRRSVNAIKSGFQAQV--G--KR Ganpr1 -------MFGE------------QDVEDEGWLGS-E--RDYEYGELLSRMYRILNPELIG--EKRRYTIPPPQVAREGSKKTVFSNVSDIARRMKRTPEHLIQFVFAELGTSGSVDGSGQLIIKGRFQPKQIETVLKRYIGEYVTCKTCKSFETNISR--DNRLWFITCESCGSRRTVAAISAGFKAQT--T--KR Gloin1 -MKKKKK-FGD-LPP--------KQLKEEAWLNS-D--RDYTYQELLGRVFQILNPELAG--EKKRYTIVPPSVHREGNKKTIFANVADICKRMHRQPEHVIQFLFTELGTSGSIDGSQRLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTILTK--ENRIFFQQCESCGSTRSVSAIKSGFKAQTEKR--RR Hisca1 LVEKK-HLFKG-LKKKK---TKKAKLAEGIWAHNAT--QPIPYNLLVTRFFTLIHPDILSS-GSKSYKIPPPQCLREGNRRTIFANITDICKRMKRSEDHVMQFLFAELVTSGSVDGSRRLVIKGRFQQKQIENVLRRYIVEYVTCKTCRSPDTELNK-GENRLYFVTCNSCGSRRSVTAIKTGFRGQV--G--RR Klula1 TMKKKKSLFAG-LKKKKK--KSKKQLEQ-------DV--GLPYQDLLSRFFKILNPELAGDRSGPKFKIPPPICQRDG-KKTIFANIQEISEKLQRSPEHVIQYLFAELGTSGSVDGQKRLVIKGKFLPKQMENLLRRYILEYVTCKTCKSINTVLKKEQSNRLFFLVCKSCGSTRSVSSIKTGFQATV--G--KR Lacbi2 SLKKR-KMFGD-IKKKKK---KKKELNDEAWLKS-D--RDYTYPELLTRFYASLNPALLSTSSRKRYTIAPPQLFREGNKKSIFANVTDICKKMHRQPEHVIQFLFAEMGTTGSVDGAGRLVIKGRFQQKQIENVLRRYMVEYVTCKTCKSPDTLLTK--ENRIFFMACESCGSRRSVNAIKSGFQAQV--G--KR Lenti61 SLKKR-KMFGD-LKKKKK---KKKELNEEPWLKS-D--RDYTYEELLHRFYAQLNPALLTSAG-KRYTIAPPQLAREGNKKTIFANVSDICKRMHRQPEHVIQYMFAEMGTTGSVDGSGRLVIKGRFQQKQIEHVLRRYIVEYVTCKTCKSPDTLLSK--ENRIFFMSCESCGSRRSVNTIKTGFQAQV--G--KR Malgl1 -------LFGG-LKKKSK---KKKELGEETWHDS-D--RDYTYQELLHRIFRTLNPALSG--EKKKYTMVPPVVQRDGSKKTMFANVIEICKRMHRQPDHVIQYLFTELGTTGSVDGSQRLVIRGRFQPKQIENVLRRYIVEYVTCKTCRSPNTLLTK--ENRIYFMTCEACGSQRSVSAIKTGFQAQT--G--KR Mellp23 SLKKKKK-FSD-LKRKKK---KKRELAEKAWLKEPD--RDYTYDELLGRFYQALHPSLSGGGVKKRYTLAPPSVHREGNKRSIWANVAEICKKMHRQPEHVIQFLFAELGTSGSVDGSGNLVIKGRFQQKQIEAVLRRYIVEYVTCKTCKSPDTLLEK--DNRLYFVTCESCGSKRSVSAIKTGFSAQI--G--KR Mnele TLKKKKK---E-FKKKKK--KKKTT----TWVTS-E--RDYTYEELLKRAVDMMNPDMQAG-EKKKYVMKPPQVLRHGSKKTSFANFLEICKMLHRTPKHVQDFFMAELGTSGSVDGYNQLLIKGRFQQKNIEGVLKRYIREYVTCHTCFSAETLLQK--DGRLQFLQCESCGSRCSVQSIKSGFQAVT--G--KR Monbr TLKKKKKISND-ILKKRA--KRSK---------G-DEGTVHPYSVLLDRVFAIINPELISG-EKKKFTMKPPQVVRLGAKKTGFVNITDICKLLHRQQDHMLAFLFAELGTSGSVDASNCLVIKGRFQQKQIESILRKYIREYVTCHTCRSPNTILAK--YNRLYFLTCEACGSRQSVANINSGFQAVT--G--RR Morel2 MFGEKKK-FGD-MKK--------GQDQEEGWIGS-N--RDYTYTELLSRVFKILNPELAG--EKKRYTIVPPSVMRDGNKKTVFANVADICKRMHRQPEHVIQFLFAELGTSGSIDGSQRLVIKGRFQQKQIEAVLRRYIVEYVTCKTCKSPDTILTK--ENRLFFLQCEACGSTRSVSAIKSGFQAQT--G--KR Mucci2 KLKKKKKMFAD-LKKKKK---KKADLADEAWLKS-D--RDYSYDELLDRVFNILNPELAG--EKKKYTIVPPSIHREGNKKTIFANVTEISKRLHRPAEHVIQFLFAELGTTGSIDGGQRLIIKGRFQQKQIENVLRRYIVEYVTCKTCKSPNTIMTK--DNRLYFVTCEHCGSTRSVSAIKTGFKAQTKED--RR Mydma T-MKKKK---D-I-KRKT--EKSGQ---AKQIAE-DELREYTYDELLKRVFDIMNPNMIEG-GKRKFVMKPPQVVRVGTKKTSFVNFTDICKILHRQPKHLLAFLLAELGTSGTVDGTNQLIIKGRFQQKHIENVLRRYIKEYVTCHTCRSPDTILHK--ETRLFFLQCETCGSRCSVQSIKSGFQAVT--T--KR Neucr2 SIKRRPSDGLD-LKKKKK--VKKKKLEAGIWAHDET--KPISYNALLSRFFALLNPDHAST-GTRSYKIPPPQCLREGNKKTIFANLPEICKRMKRADEHVTSYLFAELGTSGSVDGSRRLVIKGRFQQKQIENVLRTYIIEYVTCKTCRSPNTELSK-GENRLYFITCNSCGSRRSVQAIKTGFSAQV--G--KR Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -------MFKG-LKKKKP--SKKAKLAEGIWAHDAT--QTIPYSLLVSRFFSLIHPDLLAT-GAKSYKIPPPQCLREGNRRTIFANIADICKRMKRSEEHCTQFLFAELGTSGSVDGSRRLVIKGRFQQKGIESVLRRYIVEYVTCKTCRSPDTELNK-GENRLYFVTCNSCGSRRSVAAIKTGFRSQI--G--RR Phybl2 -----------------------ADLADDSWLKS-D--RDYTYDELLGRVFKILNPELAG--DKKRYTIVPPSIHREGNKKTIFANVTDIGKRLHRQPEHIIQFLFAELGTNGSVDGAQRLIIKGRFQQKQIENVLRHYIVEYVTCKTCKSPDTLMTK--DNRLYFVQCESCGSTRSVSAIKAGFKAQTKED--RR Picst3 SLKKKKKMFAN-LKKKKK--STKQQLEE-------DI--GFSYEQLLSRFFDILNPELAGDRSGPKFRIPPPVCQREGSKKTLFANVQEIATVLQRNPEHLIQFLFAELGTSGSIDGEKRLVLKGKFQPKQMESVLRRYIIEYVTCKTCKSMNTELKRESANRLHFLSCKACGSTRSVSSIKTGFQAQI--G--RR Plicr1 SLKKR-KMFGD-LKKKKK---KKKELNEEPWLNS-D--RDYTYPELLHRFYGSLNPSLLTSTG-KRYTIAPPSIHREGNKKSIFANVTDICKRMHRQPEHVIQFLFSEMGTTGSVDGAGRLVIKGRFQQKQVENVLRRYIVEYVTCKTCKSPDTLLTK--ENRIFFMSCESCGSRRSVNPIKSGFQAQV--G--KR Polpo SQKKKKK------KEERK--KKKTE----PWVGS-D--RDYKYSELTYRIYHLLNPELISD---QKRQMKTPVVFRDGSRKTVWANFADICQTLNRKPEHLLSYVFTELGSNGSVDGNQRLVIKGRFSSQQIEVVIRHYISEYVACRNCKSANTVLER--TNRLYFLSCNVCNSKRSVVVIKKGLE----VG--KN Pucgr2 TLKKKKK-FSD-LKRKKK---KKRELAEKAWLKEPD--RDYTYDELLGRFYQALHPSLSGGGAKKRYTLAPPSVHREGNKRSIWANVAEICKKMHRQPEHVIQFLFAELGTSGSVDGNGNLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTLLEK--DNRLYFVTCESCGSKRSVSAIKTGFSAQI--G--KR Punst1 SLKKR-KMFGD-LKKKKK---KKKELEEEPWLKS-D--RDYTYPELLHRFYACLNPALLTSSG-KRYTIAPPSLAREGNKKTIFTNISEICKRMHRQPEHVIQFMFAEMGTTGSVDGSSRLVIKGRFQQKQIEHVLRRYIVEYVTCKTCKSPDTLLTK--ENRIFFMSCESCGSRRSVNAIKSGFQAQV--G--KR Rhior3 KLKKKKKMFAD-LKKKKK---KKADLADEAWLKS-D--RDYAYDELLDRVFNILNPELAG--EKKKYTIVPPSIHREGNKKTIFANVAEISKRLHRPAEHVIQFLFAELGTTGSIDGSQRLIIKGRFQQKQIENVLRRYIVEYVTCKTCKSPNTIMTK--DNRLYFNTCEHCGSTRSVSAIKTGFKAQTKED--RR Rhoto1 -EDVKPK-FSD-LKKRK------KELAEKAWLKE-D--RDYTYTELLGRFFSLLHPSLSGGAGKKKYTIPPPQLFREGNKRSIFANIADICKRMHRQPEHVIQFLFAELGTNGSVDGSSRLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTTLTK--DNRLFFLTCSSCGSTRSVAGIKTGFQAATRAA--RR Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ALKKKKKLFAG-LKKKKK--KSKKELAK-------EV--GLPYSELLSRFFNILNPELAGDRSGPKFRIPPPVCLRDG-KKTIFSNIQDIAEKLHRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQSKQMENVLRRYILEYVTCKTCKSINTELKREQSNRLFFMVCKSCGSTRSVSSIKTGFQATV--G--KR Salro SMKKKRKSTGD-IKNKRK-----LTLKE-------D--IKHTYEELLDNVFSIMNPELAGG-EKKQFVIAPPNVVRLGVKRTGFTNFVDICK----------------------------------------------------MC-VCRC---------VFRMFM------------------------------ Schco3 SLKKK-RMFGD-LKKKKK---KKRQLDEEPWLKS-D--RDYTYQELLTRFYSLLNPALLSSSG-KRYTIAPPSIHREGNKKTIFANVTDICKRMHRQPEHVIQFLFAEMGTTGSVDGAGRLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTLLTK--ENRIFFMSCESCGSRRSVNPIKSGFQAQV--G--RR Schpo1 LPEKKKKMFSS-MKKKKK---SKKELEAHAWLKS-D--RDYYYPELLNRFFTLLNPELAG--EKRKYTIVPPSVHREG-KKTIFANISDISKRMHRSLDHVIQFLFAELGTSGSVDGSSRLIIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTILTK--ENRIFFMTCEACGSVRSVQAIKTGYQAQI--G--KR Sorma SVQRRPSDGLD-LKKKKK--VKKKKLEAGIWAHDET--KTITYNPLLSRFFALLNPDHAST-GTRSYKIPPPQCLREGNKKTIFANLPEICKRMKRADEHVTSYLFAELGTSGSVDGSRRLVIKGRFQQKQIENVLRTYIIEYVTCKTCRSPNTELSK-GENRLYFITCNSCGSRRSVQAIKTGFSAQV--G--KR Sphar STTKKKK---D-LKKKRK--KKTKDL--SIW-AQ-DCEREYAYEDLLARVYQTMNPDSAAG-ERKRVTVRPPQIVRIGTKRTGFVNFVEICKQVHRLPDHVMAYALSELGTTGSIDGDSKLVIKGRFQQKQIENVLRSYIREYVSCHTCRSPDTILTK--DNRLFFLQCESCGAQCSVATIHSGFQAIT--T--KR Spipu1 GLKKKKKMFAD-LKKKKK---KKAQLREDTWQGS-N--RDYTYNELLSRVFKILNPELVG--DKKRYTIAPPQVMKEGTKKSVFANVVDICKRMHRQPDHVIQYLFAELGTTGSIDGSQRLVIKGRFQQKQIENVLKHYFMEYVTCKTCKSADTILTK--ENRLFFLQCESCGSTRTVSAIKTGFMAQTRDA--RK Sporo1 MEEKNPK-FSD-LKKKK------KELKEKEWLKD-D--RDYTYTELLGRFFSLLHPSLSGGASKKKYTIPPPQLFREGNKRSIFANIADICKRMHRQPEHVIQFLFAELGTNGSVDGSARLVIKGRFQQKQIENVLRRYIVEYVTCKTCKSPDTTLTK--DNRLFFMTCSSCGSTRSVQAIKTGF----------- Stehi1 SLKKRSKMFGD-LKKKKK---KKKELNQEPWLTS-D--RDYYYTELLSRFYASLNPALLTSSG-KRYTIAPPSIHREGNKKSIFANIGDICKRMHRQPEHVIQYLFAELGTTGSVDGSGRLVIRGRFQQKQIENVLRRYIVEYVTCKTCKSPDTLLTK--ENRIFFMACESCGSRRSVNAIKSGFQAQV--G--KR Tapde11 SAKKKSKLGSS-LKESTL--NEQ-ALAEDSWVGT-D--RDYTYKELLGRLFDQYNPDADSG-EKRKYTIVPPNVQREGSKKTCFANVADISKRMHRTPEHVIQFIYAELGTSGSIDGAGRLILKGRFQQKQIETVLRRYINEYVTCKTCKSPDTVLVK--ENRLFFLDCEQCNSRRSVAAIKTGFSAQI--G--KR Thetr SLPAKKK------KKKRK----------GTFVAATG--EEYEYGTLLSRAFATMNPNIES--GNKQLQLEAPVLMRVGTKKTGFVNMLSICESINRSPQHVLSFMLAELGTTGTFSGNGRLTIKGRFQVKHIENVLRRYITTYVLCFNCKSSNTQLAK--EQRLTMIECGSCQSRRAVSTISSGFQAQV--G--RR Treme1 -MKKKKKLFAD-MKKKKK--KKKKELDDEAWVSE-G--RDPTYAELLDRFFRLLNPELAG--DKKRYTIVPPQVAREGTKKTVFSNIYDICRRMHRQPEHLIQFLYAELGTQGSVDGAQRLIMKGRYTQKQIENVLRKYITEYVTCKICKSPDTLLGK--ENRLYFMTCESCGSRLSVSAIKAGYQAQI--G--KR Trire2 QAERKASGGLD-LKKKKK--KKVAKLKQGVWSHSES--KTIPYTLLLSRFFTVLNPDHSLS-GTKSYKIPPPQCMREGNRKTVFANIADICKRMKRTEEHVTAYLFAELGTNGSVDGNRRLVIKGRFQQKQIENVVRKYIIEYVTCKTCKSPDTELNK-GENRLYFITCNNCGSRRSVTAIKTGFSAQI--G--KR Umbra1 MLQRQLK---------------------KSWLNS-D--RDYTYSELLSRAFKTLNPELAG--EKKRYTIVPPSIHREGNKKTIFANVADIAKRMHRNPEHVIQFLFAELGTSGSVDGAQRLIIKGRFQQKQIENVLRHYIVDYVTCKTCKSPDTILHK--DNRLYFVQCEACGSSRSVTAIKTGFKAQTKED--RR Ustma22 -------LFGG-MKKKKK--DKKKEIGEEAWQGT-D--RDYTYQELLGRVFKTLNPALSG--DKKKFTMVPPQVARDGSKKTVFANVVDICKRMHRQPEHVIQFLFAELGTIGSVDGSQRLVIRGRFQPKQIENVLRRYITEYVICKTCKRPETKLTK--ENRIFFVTCEKCGSQRSVSAIKSGFQAQT--G--KR Walse1 ALKKKKKMFAG-IKKKSK---KKKQLDQEPWLGT-D--RDYTYKELLSRTFKLLNPALVT--GAKRYTIAPPQVVRDGNKKTAFANIADICKKMHRQPEHVIQFLFAELGTSGSVDGSQRLVIRGRFQQKQIENVLRRYIVEYVTCKTCKSPETNLTK--ENRLYFMTCESCGSRRSVAAIKSGFQAQI--G--KR Zygro1 SLKKKKKLFSG-LKKKKK--KSKKQLAS-------DV--GLSYPGLLSRFFDILNPELAGDKSGPKFRIPPPVCLRDG-KKTIFSNIQDISEKLQRSPEHLIQYLFAELGTSGSVDGQKRLVIKGKFQPKQMENVLRRYILEYVTCKTCKSINTELKKEQSNRLFFLVCKSCGSTRSVSSIKTGFQAHI--G--RR [Cluster1841.fasta_al_trimmed; alignment length = 252] Allma1 -LEHTELSLKGWNWGSTELKPLFELPYSEIANVSGKNEVTLECQLVE-CRLHV-PEAIKAKAEVG--VDKGDHLVAFKELPFLTP-RGRYNVDMFLRLRGKSYDYKVNYGTITKLFLLPKPDGQTRYPFLVLQFVREEEMSVD-VNLDDMRAYDG-LTWEVVSNIFHGLTNKKITVPPAAIKCSLKA-NEGHLYLLEKSVLFVPKPPTLVAHADIAHVTFSRRTIDMVVTLRSGLSNIGREEEYLRAKKIRV Ashgo11 -LEHKDHSLRGWNWGTTDLKPTFEIPYSHISNTTSKNEVALEFELVE-MRLYV-PEELRAKAEIGE-VS-GDAIISFQDVFFTTP-RGRYDIDIYIRLRGKTYEYKLQHRQIQRIFSLPKADGQTTYPYLVLQFQKDEETEVQ-LNVEDKKQYDA-KTHVVLSHVLKGLTDTRVVVPGCAVSCSFKA-NEGHLYPLDNAFMFLTKPTLYIPFQDVSSVNISRRTFDLEVVLRSNFANISKEESFLKSKNVRV Aspfu1 -VENREHALRGWNWGKAEFRPAFEIPYSEISNTAGKNEVAVEFELVE-MRFYI-PETLMEKAEIGD-VA-GDTFATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYASIKKFFLLPKNDGQTRYPFLVMQLKLDEEISLE-LNMTEEPRYEE-PIHQVVTKIFRGLSGKKVIMPSSGVKCSIKA-NEGLLYFLDKSLIFVPKPATYVQIENIAVITMSRRTFDITVTLKAGFSNINREEEFFKAKNIRF Aurde31 -LESKDISYKGWNWGATDFKTAFEVPMKYVANSAGKTEVSVEFELVE-MRFYV-PDAIRDRAEIGQGIM-GESIVLFEDVLVITP-RGRYDIDMFMRLRGKTYDYKIMYSAINRLFLLPKADGQTKYPYLVTMFSRDQELEID-LALDEDKHYET-AMYQVVSSVFRGLTNKKITGTSPSIKCNLKA-SQGELFVLEKALFFVTKQPTLIDFADIHQVVFSRRTIDVKVVKQTGFTSMNKEEAFLKGKKVKT Batde5 -LEVVDTSLRGYNWGEPNFKTAFEIPLNQVSNTGNKNEVSIEFALVE-IRFYL-PDTVKQKADMDS-IL-SESIVSFSELLCITP-RSRFVVEMHFRLRGKSHDYKILYSAIKRMFLVPKPDGQTRYPYLVFQFGREEEIEID-LTLEEEKSYDG-PVYEVVSDVFKGLSKKKVIMSSSGLKCSQKA-NEAILYPLDKCFLAIPKPPIFFSHSDITAVTFSRKTFEVKFSLVTGFSSISREEEFCLSKRLPV Botbo1 -LEAKEISHKGWNWGATDVRTAFELPLANIANSAGKTEVSLEFELVE-MRFYV-PDMIKEKAEIGQ-VS-GESIVVFKEVLVLTP-RGRYDIDMFMRFRGKTYDYKILYTSITRLFLLPKPDGQTRYPYLVMLFSRDEEMECE-LKLDEQQRYEQ-PMHEVVAAIFRGLSGNKIIAPSTGVKANLKA-IQGELYLLGQSLIFVAKQPTLVDFSDIHQIVFSRRTFDLKVSTKSGFTSINKEESYLKGKKVRT Botci1 -LEHKEHALRGWNWGKGEFRPAFEIPYTEISNTAGKNEVAVEFQLVE-MRFYI-PDTLMEKAEIGD-VA-GDTVATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYDNIKKFMVLPKPDGQTRYPFLVMQFKKDEEVTID-LNMTESIHYEQ-PLHEVVTQVFRGLAGKKINQPAYGIKCSIKA-SEGFLYCLEKAFMFVPKPATYITYEQITVITFSRRTFDIAVGMKGGFSNINREEDFFKIKGIRV Caeel -IDQSNLFIKGWNYGQAEVKPIFEIPCTNVSNVANKNEAVLEFQLME-MRFHM-PKAVLAYAGLEA-ET-EQPICLLTDILCTTP-RGRYDIKVYIALHGKTYDYKIPIKSINRLFLVPHKDGQTRYSYLIFEFGKDEEQDLE-LALTDRRDMTG-PIYETISILFKSICNLKITVPGPAIQCTHRQ-NPGLLYPMEKGFLFIHKPAMYIRFEEISSCHFARRTFDFEIDLKYGFNAMEKEEDYLNKKNIKI Canalb1 -LEHREHSLRGWNWGKTDLKPAFEIPYSDISNSTGKNEVALEFEIVE-MRFYV-PEQLKDKADIGQ-VA-GEAIVSFSDVLFLTP-RGRYDIDMYLRLRGKTYDYKIQYEQIERIFSLPKPDGQTRYPFLVLQFVKDEETELE-LNVSDKKTYDA-PTNVVMSHCLRGLTERKLITPGAGVPCSVKA-SEGYLFPLDRCFLFVTKPTLYIPYSEISSVVMSRRTFDLEVNVIGSFSNIDREESFCKEKGVKV Cangl -VEHKEHSLRGWNWGQTDLKPVFEIPYARINNTTAKNEVAVEFEMVE-MRFYL-PEELKNKADIGE-IA-GDAIVSFQDVFFTTP-RGRYDIDIYIRLRGKTYEYKLQHNQIQRIVSLPKADGQTTYPFLVLQFQKDEETEVQ-LNLSDKKQYDS-KTHIVISHVLKGLTGRRVVVPGCAVSCSYKA-NEGYLYPLDNAFFFLTKPTLYIPFNDVSSVVISRRTFDLEVILRSNFGNISKEENFLKSKNLRV Capow -VQTSDIATKGWTWGEPRFKVAFELPLSDVSQTMKKNDITLEFQLVN-MRFVVHPQRILGKVDVAH-TA-GDVIVSLLDVNCQTP-RGRYQMDFYLTLHGQTHDFKIPFASISKTFVLPHPDGQTPYPFIVFLQTEGREISVE-LNMTETKEMSG-GEVMILARLLSAMSVRLPIQPAHGYKASYRA-SDGYLFPLENAFIFVHKPLTYIHYSDIKTVTFERKTFAFTIVTHSGFNSIPKEEQFCNAKARSK Catan2 -LDTLDISVKGWNWGSADVKLLFEVPFDEIANVSGKNEVAIELQLVE-CRLHV-PDIIKSKADLA--VEKSDVIVSFKELPFLTP-RGRYDVEMFLRLRGKSYDYKIKYSTIKRLFMLPKPDGQTQYKYLVVQFVRDDELAID-LNMDAAPSYDA-PMFEVVTAVFRGLTGQKILIPGPAIKCSLKA-NEGHLYPMERQLIFVPKPTTYLAHAEISYVTFSRRTIDMVVTMKGALSNIAREESYFSRHGVKV Cioin -LEHQELSGKGWNWGTTDFKLSFEIPLNNVSQCQNKDEVTMEFSLME-MRFFI-PDNVMAKADVLQ-VK-GTAICVFQDLQCLTP-RGRYDIRMYIQLHGKTFDYKITYTSILRLFLLPHKDGMTRYHFLILLFYKEDDLAVE-LSLPDQKDMSG-PMYEVVSRVMKHLVQRKITVPGQSITCTYKA-SSGFLFPLERGFMYVHKPPVHIRFDEIAYVNFARKSFDFEIETRSKFSNIERDQDFVHNKQLKI CocheC53 -LDNREHALRGWNWGKADFRPAFEVPYTEVSNTAGKNEVAVDFQLVE-MRFYI-PETLMEKAEIGE-VA-GDTFATFLDILHLTPSRGRFDIDMYFRLRGKTYDYKIQFDSVKKFMVLPKPDGQTRYPFLVMQFKRDEEVNLD-LNMKGQSHYEA-PIATVVADIFRGLSGKRITRPSSGVKCSIKA-NEGHLFCLDKAFMFIPKPATYISMDNIQSVTMSRRTFDITFTMKNGFSNINREENFFRAKGIKT Coere1 -LETRDISTKGWNWGKTDFRPMFDLPMSQVSNTANKNEVSVELELVE-IRFYV-PETIKDRADLGQ-VT-GDSIVQFPEILCLTP-RGRYSIDMFLRLRGKTYDYKIPYDNVQRMFLVSKPDGQTRYPYLVLQFVRDEEMAID-VNFSAREHYDE-PLYRIVANVFKGVTDKRLTEGGQGIKASLKA-SEGTLYPLEKGFLFAPKPTLFIPHSDIASILFSRRTFDLKLNMHGTFVSINREEEYMTEHGIKM Conco1 -IEVKEMSLKGWNWGKAEFKPMFEIPLNQVANTVGKNEVSIEFELVE-VRFYI-PQSIKSRADLTT-S--GETICMFPDTLLLLP-RGRYDIDMFLRLRGKTYDYKLLYNQVLNLFLLPKPDGQTRYPFLVLQFNKDEELEMD-LTFDDEKHYDA-PKHEVISNVFRAITKRKIALPGFAFKASFKA-NEGLMYPLEKCIIFAPKPVVLIPLSEIASIMFSRRTFDMKINLKSGFSSVNREETYLKSKKIKI Conpu1 -LEVKDVTFKGWNWGVTDIKTSFELPLGQVANSAGRTEVSLEFEMVE-IRFHV-PEAIKEKADIGQ-VM-GDLVLSFDDVLILTP-RGRYDLDMFLRLRGKTYDYKISYSSIARLFLLPK-DGQTRYSYLVMQFAREEETTAE-LNMAEKKHYED-PTFEVVSGVFRALSQKKIIGSGPGIKANLKA-VQGDLFMLEKYIFFVSKQPTLIELADVHQCVFSRRTFDLKIVTKSGFTSINKEEGYLKDKKIKI Copci -LETQEVSFRGWNWGVADFKTAFELPLNQVANSAGRTEVSLEFEMVE-IRFHV-PETIKERANIGQ-IT-GNMILSFEEVLVLTP-RGRYDMDMFLRLRGKTYDYKIVFTSISRLFLLPK-DGQTRYQYLVMQFTREEEITAE-LNISDKKNYED-PTYEVISSVFRALSGKKIIGAGPGIKANLKA-IQGDLFMLEKYIFFVSKAPTLIEISDIHQVVFSRRTFDLKIITKSGFTSINKEEAYLKDKKVRV Croqu1 -LETKDMSLRGWNWGKVDVKPAFEVPLAYVHNAN-KTEVAIEFQMVE-LRLYV-PDLVMEKAEIGR-VQ-GEGIVTFPDVLCTTP-RGRYDVDMYLRLRGKTYDYKVLYSSIQRLFLLPKPDGQTRYPFLVMQFAKDEEMDAE-LNLDEHNKVEG-QAHEVVSIIFKGLAKKKIIFPQTAIKCSIKT-NEGLVYFLDKYILFISKQPVLVALSDLHSVKFARRTFDLVLKKKDDLSSLSREEDYFKDKGKKV CryneH991 -LETRDTSLKGWNWGEAQVKTAFDVPLSQVANSAGKYEVALEFEMVE-MRFYI-PSLIKEKADIGA-VV-GDSIVVFEDCLILTP-RGRFSIEVYIRLVGKSTDHRVPFTSIHRIFLLPKLDGATRYPFLVAQWPKDEVVNAE-LNLTDEKTYEA-TTFQVVSRVLKALTGKKVTPPGNGIRANVKA-VQGELYFLEKGLIFISKQPILIDFSKTDSISFSRRTFDMRVVSKTGFSAINKQESFLQSKNIRL Crypa2 -LENKDHSMRGWNWGKAEFRPSFEVPYSEISNTAGRNEISIEFQLVE-MRLYI-PQTLMDKADIGD-TA-GDTVATFQDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYEAVKKFMVLPKPDGQTRYPFVVMQFKRDDESTID-LNMSEEAHYEE-PMHQVVTKIFRGLSNKKVSVPAQAIKCSIKA-SEGFLYLLEKAFMFVPKPATYISYEQTQSVTFSRSTFDITVQMK-GFSNISRDDIFFKLKGLRV Debha1 -LEHKEHSLRGWNWGKTDLKPDFEIPYSEISNSTGKNEVAVEFEMVE-MRFYI-PEQLKDKADIGQ-VA-GEAIVSFSDVLFLTP-RGRYDIDMYLRLRGKTYDYKIQYNQIERIFSLPKPDGQTKYPFLVMQFAKEEEIELD-LNVSEKKSYDS-QTHLVMSHCFKGLTERRLVVPGPGISCSLKA-SEGYLYPLDRCFLFVTKPTVYIPFSEISSITMSRRTFDMDITLRGSFGSIEREENYCLQKGLRI Dekbr2 -LEQREHSLRGWNWGKTQLKPAFEIPYSQIANTTGKNEVSVEMELVE-LKLFI-PDELKEKADLGQ-VV-GEMIVSFGEVLFLTP-RGRYDIDMYLRLRGKTYDYKVQYKQIQRIFSLPKVDGQTKYSFLTLQFDSQEEIEVE-LNLDDNKTYSN-YTYMVLTSIFKGFTDRRVVVPGVAISCSVKA-NEGHLYPLDKCLIFVTKPTILLPFSDVHEVVFSRKTFDMEVVLKYGFGNIDRKETFLKTRNLRV Dicdi PLEIIELSSKGCNWGEVKVKVGFEFPISEVSQSNNKNELTLEFTMVE-MRFFT-PQTIMNKSDVSN-V--GKSLVVFSAIQFLTP-RGRIDIEMYLKLHGKTHDYKVPYESISRLFQFFRPDGQTKYAHLVIQFQAEENIHLE-LNLTDSPIMNG-NANALICKILKALTGKKITIPGNSIKCSLKA-NEGYLYPLERCFFFVHKPPTYIKFEDISNIEFARRTFDLSINLKNSFVNIQREENFLKEKKLSI Dmel -MVEKEMCVKGWNWGTARFKTIFEVPLSHVSQCTGKNEVTLEFGLLE-MRFHI-PQNVMSKASVIS-AS-GESIAIFREIQILTP-RGRYDIKIFFQLHGKTFDYKIPMDSVLRLFMLPHKDGQTRYHYLVLLFAPDEETTIE-LPFSEEKEISG-PVYEVMGKVMKVLIGRKITGPGAAVGCSFKA-AAGYLYPLERGFIYIHKPPLHIRFEEISSVNFARRSFDFEVTLKNGFSSIEKEEDYITQKKLHV Enthi -MQEKEYCVSGFNWGRIDIYLIFKMNPKDFTKSSNKTEVSIEFALSE-IKFFA-PDKIAEVTP-TN-AA-GKEVCLFENIGFLSP-KGHYDVKIYVRVQNKTYDFKINYKDIARYYKLRK-DGKSVYECLVMELSSNEEVTAE-LHLTKEESMTD-NELDLFVELFRSLCNVPIISSGHFLKCNLST-NEGFLFPMSDSFIFVFKRIRIIMFKDIKSVDILRKTFDFVINLKGRFTGMNRNEGYLKESQLKL Falba -LTPVEHNVRGHNWGDVDFRELFLLPYSDIISTIMKNEVTLEMQLVD-IRFFV-PEHVKERIELAASGA-SSKIATLSELSLLIP-RGRFDVVFYLRLHGKTYTHRIKYEQILTALRLPMGDGQTSYEYVIILPLGEDYRTVE-VSLTDQDLYENRPLGSILHDLLTGLASVAVSLPVGGIKCSYKAFGGGRLYPVRNGLLYVPRPTVMINFRDVLSVKFLRGTFDVQFTMRSDFRQLPAGITFLENNRVLV Fomme1 -LENKEISFKGWNWGATDFKTAFELPLQKVANSAGRTEVSLEFELVE-IRFYV-PDAVKEKAELGE-VT-GNVIVNFEEVLVLTP-RGRYDVDMFLRLRGKTYDYKINYDGISKLFLLPK-DGQTRYHFLVMQFDREEEIRAE-LNIEEQKHYEA-SSFEVISSIFRALSKNKIIGSGPGIKANLKA-VQGDLFILEKYLFFVAKAPLLIELSDIHQVNFSRRTFDLVVVTKSGFSSLNKEEGYLKGKKLRV Fusgr1 -LESKEHALRGWNWGKAEFRPAFELPYSEIGNTAGRNEVAVEMQLVE-MRFYI-PETLIDKAEIGE-TA-GDTIATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYEAIKKFMVLPKPDGQTRYPFVVMQFKKDEEVTID-LNLNEEPHYEE-PLHQVVAKIFRGLGNRKISSPAYGIKCSIKA-SEGFLYCLEKAFMFVPKPATYIAYEQTQSVTFSRSTFDITVLLKNGFSNISREDSFFKLKGLRV Galma1 -LETIEASWKGWNWGVADFKTAFELPLQHVANSAGKTEVSLEFELTE-IRFFV-PDTIKEKAEIGQ-GT-GDLILSFDEVLVLTP-RGRYDMDMFLRLRGKTYDYKVLYQSIAKLFLLPK-DGQTLYQYLVMQFTREEEITAE-LNMSDKKNYED-PTYEVVSSVFRALAGKKIIGSGPGFKANLKA-IQGDLFMLERYIFFVSKQPLLIELADIHQLIFSRRTFDIKIVTKSGFTSINKEEAYLRDKKIRV Ganpr1 -FDVREYSLKGWNWGRHAFRAAFEIPLSQVSNTPTRNEVVLEFELVE-MRFYI-PESVKEHADLGG-AA-GEAVLEFAGVLCLSP-RGRFTLSLHFRLRGRTHDYRVDYTRVQHLFLLPKPDGNTPYRFLVFQFGEAEEVEVEMRDVEGRPSYDG-ETFKIVSEVLSVVTRKKVITDAPGLKCNLKA-NEAYLYPLGRCFFSVFKPSVHIAFADVEQITFQRKMFDVVIELKKGYGQIQREDTFARSRGIRV Gloin1 -LETKDLSVRGWNWGKTEFKTAFEVPLSQVANSANRNEVNIEFELVE-MRFYI-PETVKDKADLGQ-VS-GEGLALFQDILLLTP-RGRYDIEVFFRLRGKTYDYKIQMAAVVNLFLLPKLDGQTLYHFLVLQFKQDDEKELV-LNIEELPRYEC-PIHEAVSAVFQGLTKKKINRPSVAVKASLKA-NEGYLYPLEKCFLFVPKPPTYLPFSEILSVTFSRRTFDMKFNMRSGFSSLNREELYLRSKNIKT Hisca1 -LENREHALRGWNWGKAEFRPAFEIPYSEISNTAGKNEVAVEFELVE-MRFYI-PETLMDKAEIGD-VA-GDTFATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYQSIKKFFLLPKNDGQTRYPFLVMQLKLDDEISID-LNMTDEAHYEE-PIHQVVTKVFRGLSGKKVVMPSSGVKCSIKA-NEGLLFCLDKSFMFVPKPATYVQIENISVITMSRRTFDITMTLKGGFSNINREEEFFKAKNIRF Klula1 -LEHREHSLRGWNWGKLDLKPTFEIPYTHINNTTAKNEIALEFELVE-MRLYV-PEELRSKADIGE-IS-GDAIISFQDLFFTTP-RGRYDIDIYIRLRGKTYEYKLQHRQINRIFSLPKADGQTSYPFLVLQFQKDEETEVQ-LNVEDKKQYDA-KTHIVLSHVLKGLTGRRVIVPGCAVSCSYKV-NEGHLYPLDNAFLFLTKPTLYIPFQDIAAVNISRRTFDLEVVMRANFANISKEETFLRSKNLRV Lacbi2 -LETREVAFKGWNWGVTDFKIAFELPLRQVANSAGRTEVSLEFEMVE-IRFHV-PDMIKEKAEIGQ-VS-GDMILSFEEVLVLTP-RGRYDMDMFLRLRGKTYDYKILFGSISKLFLLPK-DGQTRYQYLVMQFTREEEITAE-LNMSEKKNYED-PTYEVVSSVFRALARKKIIGSGPGIKANLKA-IQGDLFMLEKYIFFVSKQPTLIELSDIHQVVFSRRTFDLKIVTKSGFTSINKEEAYLKDKKIRV Lenti61 -LETKEVSFKGWNWGVTDFRTAFELPLTNVANSAGRTEVSLEFEMVE-IRFYV-PDLVKEKAELGQ-VS-GDIILSFDEVNVLTP-RGRYDVDMYLRLRGRTYDYKILYGSISKLFLLPK-DGQTRYQYLVMQFNREEEITAE-LNMAEKKNYED-PTYEVVSGVFRALSKKKIIGAGPSVKANLKA-VQGDLFLLEKYIFFVSKQPTLIELSDIHQVVFSRRTFDVKIVLKSGFTSLNKEEAFLLEKKVKT Malgl1 -LETIEISTRGWNWGSAEVRLAFSLPLANIANSAGRTEVSMEFQLVE-MRLYI-PNAIKAKADIGQ-VA-GDGILVLKEVLILTP-RGRYDIDLFLRLRGKTYDYKILYSSITQLFLLPKPDGQTRYPFLVLQFPREEEMDAE-LNLDEKKRYEE-PTFRIVTNLFRVFSQQKVHVPTESVRCNVKA-NDGMLYPLNKSLIWVSKQPILISYHDVHQFVFSRKTFDLRVELQHGFQSISREENFFAERKLRV Mellp23 -LETKDMSLRGWNWGKADVKPAFEVPLAFVHNAT-KTEVALEFQLVE-LRLYV-PDMVMDKAEIGR-VQ-GEGIVTFPDVLCTTP-RGRYDIDMYLRLRGKTYDYKVLYSSILRLFLLPKPDGQTRYPFLVMQFAKDEEMDAE-LNLDDHNKVEG-QAHEVVSIIFKGLARKKIIFPQTAVKCSMKT-NEGLIYFLDKYILFISKQPLLVALSDLHSVKFARRTFDLVLKKKDEFSSLSKEEEYFKGKGKKV Mnele -FIEKEPFVKGWNWGSVDFKPLFEVPLPDVSTAVNKNEVTVEFSLVE-MRFYV-PKSVMKYADVIK-AT-GDVIVKFEQVLLQTP-RGRYDVDMYLRLHGKSYDYKIPYTTMIRMFLLPHNDGQTRYPHLVIQFIKDDWSDLT-LELDEQKEMAG-PTYETFSKVMKFVVGQKIFVPGQAIACSHKA-NSGFLYPLEKGFMYVVKPPVHIRFDEVSSVNFSRRSFDLEIETNTGFASIEKKEDFLKSKKIRI Monbr -IQSHKTSVKGWTSGRTEFGVAFEVPLASLTAAQQRHEAILEFQVVESMRFFV-PSEINERTAVNR-IS-GKAICMIENVKLVVP-RGTHDVEFYLRLHGKKFDHKIQYENVQRMHLLTQ-D---------------------------------------------------------------------------------------------------------------------------------- Morel2 -LETKEMSVKGWNWGETDFKEMFEIPLNEVTNTTAKHEVMIELQLVE-MRFYV-PNSIKNEADIGD-AAPGDGIVLFSDTLCLTP-RGRYDIDMFLRLRGKTTDYKISYTSIIKLFLLPKPDGQTRYPFLVFQFVREEEIDVS-LNLDDEKKYES-RTYEVVSTLFKTLTGRRVTIPSSAIKCSMKA-NEGVLYPLDKSFLFIPKPPTFIPHSEIGSVTFSRRTFDLKFNMKSGFSSINREEEFLQNKKIKT Mucci2 -IEVKEVSVKGWNWGKTEFKTMFELPLAQAIATPGKNEVAINFELMD-ITFYV-PETVKSKLELSQ-MT-TENIVQFQEALCLTP-RGRYNIDMYLRLRGKTYDYKILYSNIIKLFLLLKPDGQTKYPFLVFQFVREEEIDVD-LNLEDQKHYDA-PTYEVVSNVFRALTGRKVTVPGNALKCSMKA-NEGFLYPLEKSLLFIPKPPTFIPLNEIGVVTFSRRTFDMKFNMKSGFSSINREEEYLKQKKIKI Mydma -LEDQDLSVSGWNWGEAKFKAAFEIPLQDVSQATGKNEVTIEFQLME-MRFFV-PDQIMSKADIIQ-AT-GDAIVTFDEVACLTP-RGRYSIRVYLQLHGKTYDYKIPRTAIVRLFLLPHQDGNTRYPFLILQFERDEEMSCE-LNLTETRKMSG-AVFEIVSRVLKEICQQKITVPGSAISCSYKA-SNGLLYPLEKGFMFVHKPPVYIRFDEISSVNFARRTFDFEMDLNNGFSSLPKDEDFVNQKKLRI Neucr2 -LENKEHSLRGWNWGKAEFRPAFEIPYSEISNTAGRNEIAVEFQLVE-VRFYI-PDTLIEKAEIGE-TA-GDTIATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYDAIKKFMVLPKPDGQTRYPFVVMQFKADEEVTLD-LNITEQSHYEQ-PLHQVVAYIFKGLANKKVTTPAYGIKCSIKA-SEGFLYCLEKAFMFVPKPATYISYEQTQSITFSRSTFDITVHMKNGFSNINREDEFFKLKGLRV Orpsp11 -LEQKELSLRGWNWGRTEFRQVFEVPLTEVANTT-RNEVALEFTITE-MRFYI-PDTIKQKADLRM-VT-GEGIGSFQDLLCLTP----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -VESREHALRGWNWGKAEFRPAFEVPYSEISNTAGRNEVAVEFELVE-MRFYI-PETLMDKAEIGD-VA-GDTFATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYSAIKKFFLLPKNDGQTRYPFLVMQLKLDEEISLE-MNMTEQPHYEE-PIHQVVTKVFRGLSGKKVIMPSQGVKCSIKA-NEGLLYFLDKSLMFVPKPATYIQLENIAIVTMSRRTFDITVSLKGGFSNINREEDFFKAKSIRI Phybl2 -VESKELSVKGWNWGKTDFKTMFELPLAQAIGAPGKNEVSINFELMD-VIFYV-PETVKSKLEFSQ-MT-TENIVQFQEVLCLTP-RGRYNIDMYLRLRGKTYDYKIQYSSIIKLFLLPKPDGQTKYPFLVFQFVREDEIDVE-LNLDELKHYEA-PTYEVISTIFRSLAGRKVTVPGHALKCSMKA-NEGYLYPLEKCFLFIPKPPTFIPLNEIGVVTFSRRTFDMKFHMKSGFSSINREEDFMKQKKIKI Picst3 -LEHKEHSLRGWNWGKNDFKPAFEIPYDVISNSTGKNEVAIEFEMVE-MRFYV-PEQVKDRASIGQ-VA-GEAIVSFSDVLFLTP-RGRYDIDMYLRLRGKTYDYKIQYKQIERIFSLPKPDGQTRYPFLVLQFAREEETEVE-LNLSEKKSYDA-PTQLVMSHCFKGLTERRLIVPGPGISCSLKA-SEGYLYPLDRCFLFVTKPTIYIPFSEISNITMSRRTFDLEINVRGSFGSIDREENYCAEKGIRV Plicr1 -LEGKEISFKGWNWGVTDFKTSFELPLNHVANSAGRTEVSLEFEMVE-IRFHV-PDAVKEKADIGQ-VS-GDIILSFEEVLVLTP-RGRYDVDMFLRLRGKTYDYKIVYTSISRLFLLPK-DGQTRYQYLVMQFTREEEITAE-LNMDEKKNYED-PTFEVVSGVFRALSKKKIIGAGPGIKANLKA-TQGDLFMLEKYIFFVSKQPTLVELSDVHQVVFSRRTFDLKIVTKSGFTSINKEEAYLKDKKVRI Polpo -LAVKELSTKGSNFGIAKVKTAFEFPISDVSQSNNKNELTIEFSIVE-LRFFA-PDTLLRKSDISN-V--GKSIVVLNDIHFLTP-RGRFDIEMYLRLHGKTHDYKVSYDTISKLFQLPRQDGKTKYNHLVIQLSKENNNVLH-LNLSPSPTMEG-TLYVIVRRILTSLTENKIIVPGNSIKCSLKA-NEGYLYPLDRSFFFIHKPPTLIKYTDIQIVEFSRRTFDLNITLKDSFTNILKEENFIQNKQIKI Pucgr2 -LETKDLSLRGWNWGKMDVKLAFEVPLGLVHNSS-KTEVAVEFQLVE-MRLYV-PDLIMEKAEIGR-VQ-GEGIVTFPDVLCTTP-RGRYDLDMHLRLRGKTYDYKVLYSSIQKLFLLPKPDGQTRYPFLVMQFAKDEEIDAE-MNLDEDNKIEG-QAHEVVSIVFKGLAKKKIIFPQSAIKCNMKA-NEGLLYFLDKYVLCISKQSILINLADLHSVKFARRTFDLVLTKKDEFSSLSREESYFETKGKKI Punst1 -LETKDVSFKGWNWGVTDFKTSFELPLNHVANSAGRTEVSLEFELVE-IRFYV-PDAIKEKAEIGQ-VA-GDIILGFEEVLVLTP-RGRYDVDMFLRLRGKTYDYKIIYTTIQRMFLLPK-DSQTRYQYLVMQFNREEEITAE-LNLSEKKNYED-PTFEVVSGVFRALSGKKIIGVGPGIKCNLKA-IQGDLFMLEKYVFFVSKSPMLIEISDIHQVVFSRRTFDLKIVTKSGFTAINKDEAFLKDKKVRV Rhior3 -LEVKEISVKGWNWGKADFKMMFELPLAQAIATPGKNEVAINFELMD-CTFYV-PETVKSKLEFSQ-MT-TENIVQFQEILSLTP-RGRYNIDMYLRLRGKTYDYKILYSNIVQLFLLLKPDGQTKYPFLVFQFVREEEIDVD-LNLEDQKHYDA-PTYEVVSNVFRALTGRKVISTSYAMKCSMKA-NEGFLYPLEKSLLFIPKPPTFIPINEIGVVTFSRRTFDMKFRMTSGFSSINREEDYLKQRKIKI Rhoto1 -IETKDISVRGWNWGVAEVKPSFTIPLNVVQNTT-KAEVALEFEVSE-MRLYI-PDAVKEKAAIGL-IA-GETICTLPEVLCTTP-RGRFDIDIYMRLRGKTYDYRVTYQQVQRLFLLPKPDGQTRYPYLVMQFNKDEVMELE-LNLDEKQKYDE-RGYEVVSLLFRVMTQKKVVTPGAAVKCNLKA-NEGQLYFLEKQLLFISKQPTLVSFNEISAVVLARRTFDLAIRLKDSFSALSKEEDFLSMKKIKV Rozal11 -FEVQELSVKGYNWGQTEFKTMFEIPVDQVSNAAAKNEISVEMQLTE-IRFYI-PKRLKSLAELST-KS-GEKIVTISDIQCVTP-RGRYEFDMFLRLRGKSYDYKIMYSSIVKLFLLPKPDGQTRYPFFVLQFAKDDEMELEDLNFDERNRYEG-PFYEIVSLLIKTLSQKKITVPGSGIKCSMKA-SEGTLYPLERSFLFIPKPTIFMPHSDISSVEFSRRSFDLKITMRSGFSNISKEESFLIEKKIKV Sacce1 -VEQREHSLRGWNWGKTDLKPTFEIPYARINNTTSKNEVGIEFELVE-MRFYI-PEELKEKADIGE-VA-GDAIVSFQDVFFTTP-RGRYDIDIYIRLRGKTYEYKLQHRQIQRIVSLPKADGQTTYPFLVLQFQKDEETEVQ-LNLEDKKQYDA-KTHIVLSHVLKGLTDRRVIVPGCAVSCSFKA-NEGYLYPLDNAFFFLTKPTLYIPFSDVSMVNISRRTFDLEVVLRSNFANISKEEQFLKSKNLRV Salro -IKIVELSLKGNNSGSARFKPAFEVPLNAVGNVSQKYEASIDFQRVESMRFLVIPENVKARASIAE-YT-SRAICTIGKLSFLVP-RGRFDVELYMQLRGSTYDHRLFYDYISHIYLLPRPDGQTRYPHVLLQFTREHEGADVVVNVTSEVTETG-PLASILSRLLKALTKRKIITPGAAVNCTYKA-NRGTLYPLDRGFLFLHKPLLHISIVRNLRVTFDRKSFDMRLLHPERFRGLGQDEDFLRLKRVAI Schco3 -IETKEITFKGWNWGDTDFRVAFELPLQNVANSAGRTEVSLEFEMVE-IRFHV-PDLIKDKAEIGQ-VS-GDMILSFEEVLILTP-RGRYDLDMFLRLRGKTYDYKIVYTSISRLFLLAK-DGQTRYSYLVMQFTHEEEITAE-LNMTDEKSYEK-PTYEVVSAIFKGLTGKKIIGVGPGIKANLKA-VQGDLFILDKQLFFVSKQPLLIDFSDIHAAIFSRRTFDLRVETRSGFSSIAKEEKFLKASKLKV Schpo1 -IEQKEFSIKGWNWGEANFRPAFEIPISAVTNTSGKNEVALEFELVE-MRLYV-PESLKERADIGQ-AA-GDAIVSFSEILLLTP-RGRYDIDMYMRLRGKTYDYKVEYSSINSLFLLPKPDGQTRYPFLVTQFVRDEDMEVD-LNIEEKASYDQ-PAFEVVSQIFRGLTGRKVTTPAAAVKCSYKA-NEGQLYCLDKSFLFIPKPTLLMNTSDITRVTLSRRTFDLTFTLRSGFSNINRVEAFLESKQIKI Sorma -LENKEHSLRGWNWGKAEFRPAFEIPYSEISNTAGRNEIAVEFQLVE-VRFYI-PDTLIEKAEIGE-TA-GDTIATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYDHIKKFMVLPKPDGQTRYPFVVMQFKADEEVTLD-LNITEQSHYEQ-PLHQVVAYIFKGLANKKVTTPAYGIKCSIKA-SEGFLYCLEKAFMFVPKPATYISYEQTQSITFSRSTFDITVHMKNGFSNINREDEFFKLKGLRV Sphar -------------------KSCFEVPASSIQNVMKKQELVIEF------------KALSKITNQGA-KK-SKAIASFPDMTCKTP-RGRYEMELYVHLHGAKYSYKLHHKAIQRIFLLPKPDGQTSYPFFIMGLEDDDKIDVE-MNMDENKIMSG-PLFEVLSRVLKILSGKKITVPSPCMSCSLKN-ETGLLYILESALMFVLKPPTYVHFKEILMAEFDRRTFRLNIETKTMFSNITAEETFLVEKKVNV Spipu1 -LERKELSVRGWNWGSIEFHPAFEIPLNEVANAASRNEVSVEFALVE-VRFFV-PETIKQKSDFGG-AF-GESIASFENLLCLTP-RGRFEVDMHFRLRGKSHDYKVLYDSVIMLALLPKPDGQTRYPFLVFQFEREDEMEIS-LAMDDKKDYDG-PIYEVVSDILKGLSGKKLTTPGSGIKCAYKA-NEAFLYPLEKLILSIPKPAIYFSHNDIAAVTFARKTFEIKFNLRDGFSSIAREEAYFRAKKIQV Sporo1 -IETKDTSVRGWNWGVAEVKPSFTVPLSLVQNTT-KAEVALEFEISE-MRLYI-PDAVKEKAEIGQ-VV-GDTICTIGEVLCVTP-RGRFDIDIYMRLRGKTYDYRVTYQQVKRLFLLPKPDGQTRYPYLVMQFAKDEMMELD-LNLDEKQRYDD-PAYEVVSLLFRVLTEKRVTTPGAAVKCNLKA-NEGQLYFLEKQLLFVSKQPTLVLFSEISAVILARRTFDLSIKLKDSFSAVNKEEEFLTMKKIKV Stehi1 -LEQQEVLFKGWNWGITDFKTAFELQLQHVANSAGRTEVSLEFEMVE-IRFFV-PDAIKEKAGSEL-AT-GEKILSFEEVLVLTP-RGRYDVDMFLRLRGKTYDYKIVYTSISKLFLLPK-DGQTRYQYLVMQFSREEEITAE-LNMTDKKDYED-PTFEVVSSVFRALSGKKITSTGPGIKANLKA-VQGDLFLLEKSIFFVSKQPVLVELSDVHQAVFSRRTFDLKIVTKSGFTSLNKEEAFLKEKKVRV Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr -LEEDTVSARGINWGELGVSLILSLPLGDVAQARKSDELVFDFEVMQRIAFTI-PKQVVEEGDLEL-AS-GAALCTLEQMQLKTP-RGRFTFEMYMILRGRAQDHKIMYSTVTRLYLLPPPDGQTRYPHLLVSFKTSDSISVS-LNMTQEPEMSG-AIFEVVPLIIKHFVGRTIAAPSKAVRCSVGA-SDGLLFPLARSMFFIHKPALYIRFSEITSVEFARKTCDLVVHTKSGFINIPRADNYLNTAGVKV Treme1 -LETKDPALKGYNWGKVNVKTAFEIPLSAVANSAGKNEVSLEFEMVE-IRFYV-PSAIAEKADIGE-VV-GDSIVSFSDVLILTP-RGRYTLDFYVRLLGKSTDYRVPFTSVRRLFLLPKLDGATRYPFLVLQWPKDEEVDAE-LAMTDKKKYDA-PSFTVISQVIKSFTGKRVTPPGNGIKANVKA-VQGELYFLDKGLIFIAKQPILIDFSKTETISFSRRTFDMRVVSRAEFSSINKEEAFLKEKGVRV Trire2 -LENKEHALRGWNWGKAEFRPAFELPYSEIGNTAGRNEVAVELQLVE-MRFYI-PETLIEKAEIGE-TA-GDTIATFLDVLHLTP-RGRFDIDMYFRLRGKTYDYKIQYEAVKKFMVLPKPDGQTRYPFVVMQFKKDEEVTID-LNIDEEAHYEE-PLHHVVAKIFRGLGNKKISSPAYGIKCSIKA-SEGFLYCLEKAFMFVPKPATYIAYEQTQSVTFSRSTFDITVVMKNGFSNINREDSFFKLKGLRV Umbra1 -LESKELSLRGWNWGKTEFKEMFELPLSQAIGAPGKNEVAVNFELMD-ITFYI-PENVKSKLELGQ-LT-SENIVQFQEVLCLTP-RGRYNIDMFLRLRGKSYDYKIMYSSIIKLFLLLKPDGQTKYPFLVFQFVRDEEIDVD-LNLDEQKTYDA-PTYEIVSTVFRALTGRKVTVPSLGIKSSMKA-NEGYLYPLEKCFLFIPKPPTFIPHSEIGVVTFSRRTFDMKFSMKTGFSSINREEEFIKSKKIKM Ustma22 -LEAKEVSTRGWNWGQAKIKLAFELPLSHLANSA-KTEVSMEFQLVE-MRLYV-PEALKSKADIGQ-VA-GDSIVVFKEVLVLTP-RGRYDIDVFIRLRGKTYDYKILYSSMNKLFLLPKADGQTRYPYLVLQFPREEEMDAE-LNLDEKKRYEE-PTFRIVTNIFKVLSGQKVATPTTSIKCNVKA-ADGNLYPLEKSLLWVSKQPVYVPYSEIHQAILSRKTFDLRVATKSGFQSISREEAWLADRKVRI Walse1 -LETREISFRGWNWGRTEYRTMFEIPVQKIANSASKTEVSLEFELVE-MRFYI-PDQIKDKAEIGK-VS-GDGLVVFNDILVVTP-RGRYEIDMYIRLRGKTYDYKILYSSIKRLFVLPKTDGQTRYPYITMQFPNNEELDAT-INMEEQKHYDA-PAYQVVAQVFRGLSGKDITTPKPAIKCNVKA-NQGDLYVMEKSLFFVTKQPIYIPFSDIQSAQFARRTFDLRIVQKSGFSGINREEEFFTNKKIKT Zygro1 -VEPKEHSLRGWNWGKADLRPSFEVPYARINNTTSKTEVAIEFELVE-MRLYV-PEELKEKADIGE-VS-GDSIVSFQDVFFATP-RGRYDIDIYIRLRGKTYEYKLQHRQIQRIVSLPKADGQTTYPFLVLQFQKDEETEVQ-LNLEDKREYDA-KTHIVVSHVLKGLTGRRVMVPGCAVSCSYKA-NEGYLYPLDNAFFFLTKPTLYIPFMDVSSVNISRRTFDLEVTLRGNFANISKEEQFLKARNLRV [Cluster1842.fasta_al_trimmed; alignment length = 293] Allma1 TGAVKNYISRRQALKKLQISLKDFRRLCILKGIYPREPANKKKVN-KGSTAPTTWYYRKDIQYLLHEPLLAKFREWKIFARKMARLLTKRQEALEENKPVFTFDHLIRERYPTFTDALRDLDDALSMIFLFATMPSCQRKSAEFLHYVIQSRCLRKTFISIKGIYYQVEIKGQITWIVP--HQFSQTVPTDVDFKVMHTFLQLYDTLLGFVMFRLYNLKYPPALFYISREVPRSAVEFVLRAFGRITHHLVDRPFVQPQWVFDCVNSLPPHLSPFMMSNKDKKLFEAIKKQDE Ashgo11 TGNARNFVTRSQAVRKLQISLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPTTFYYYKDIQYLQHEPVLAKFREHKTFAKKLTRALGRGEKKLEENKSHYKLDHIIKERYPSFADALRDLDDALNMLFLFANLPAAQELCNQWLALIARERLVRKVFVSIKGVYYQANVRGEVRWLVP--YKFPENIPSDVDFRIMLTFLEFYSTLLHFVLYKLYGLVYPPKLFYIGREVPVDILEFLIVSCGKVTHQLVDRPYIQPQWVFDSINSLPPHLSPWMMSNKQRKLFKKMQKEQE Aspfu1 SGQAKNYITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKAS-KTSTPNTTFYYTKDIQYLLHEPLLRKFREQKAVAKKIARSLGRGEARLEKN-PKLTLDHVIKERYPTFIDALRDLDDALSLLFLFANLPSCQRLCHEFQHYLITTNSLRKSFLSIKGIYYQATIQGQILWLVP--YRFVQRVNGDVDYRIMATFVDFYTTLLGFVNFRLYGLRYPPKFFYISREAPRAPLEFILRAFGRITHQIVDRPYVQPQWVWDCINTLPPHLSPWMMSRKKRKLLEKMKQSEE Aurde31 AGAAKAYVTRTHAVKKLQISLADFRRLCILKGIFPREPRNKKKAN-KGSSVPTTFYYAKDIAYLAHEPVLKKLREHKAFAKKLARALGRAEKSLEDNKPVYTLDHIIKERYPTFIDAVRDIDDALCLVALFATLPACARLTAEWQLYVMHTRALRKVFLSIKGVYYQAEVMGQITWLVP--YQFSQQIPPDVDARVMLTFLELYQTLLGFVFFKIYGLSYPPQMFFLSRESPRTILEFVIRAFGSITHVIIDRPYVQPQWVVDCINILPPHLSPFMMSNKKRKLYEKMKRAEE Batde5 EGNVLKYISRSQAIKKLQITLTQFRRLCILKGIYPVEPKNKRQLA-KGSTTWQTYYFRKDIQFLLHEPVLRVLREQRSHKLKLNKAIGKREKRLYENRPVYTLDHIIKERYPCFVDALRDLDDALSMIFLFATISACQRLSAEFQHYVIISRSLKKTFVSIKGIYYQAEIRGQITWITP--FQFSQDAPIDVDFRVMDTFLEIYEPLVGFVNYKLYNLVYPPKIFWLPREVSRNSLEFIIKSFGCITHHVCDRPYIQPQWVYDSVNTLPPHLSPFMMSKRDKKLYDGIKKAEH Botbo1 KGAAKAYVTRSAAVKKLQCSLADFRRLCILKGIFPREPRHKKRAN-KGSTAPTTFYYAKDIAYIAHEPVLRKLREHKAFAKKLSRALGRGEKSLEDHKPTYTLDHVIKERYPTFIDALRDIDDALCLITLFASLPSCYRLSSEWQLYVMHTRSLRKVFLSIKGVYYQAEVMGEVTWLVP--YMFTQQIPTDVDTRVMLTFLELYQTLLGFVFFKLYGLVYPPPLIWLTIGTPRPLLEFAIRAFGSITHVIIDRPYVQPQWVVDCINTLPPHLSPFMMSNKQRKLYERMKRTDE Botci1 SGQAKNFITRTQAVRKLQISLPDFRKLCIWKGIYPREPRNKKKAS-KSSTHSTTFYYTKDIQWLLHEKIVDAFREQKALERKISKALGRGDARLERNKTKYNLDHIIRERYPTFIDALRDLDDCLSMLFLFANLPSCEKLCLEFEHYLIVSNSLRKSFLSIKGIYYQATIQGQILWLVP--YRFNQRVTGDVDFRIMGTFVEFYQTLLGFVNFRLYGLVYPPKFFFLSRETPRQPLEFILRAFGSITHQVVDRPYIQPQWIWDCINQLPPHLSPFMMSRKKRKILEKMKKDAE Caeel AGAAVAYMSRKQALKKLQLTLKDFRRLCIIKGIYPHEPAHKKQAN-KGSTANKVFYYRKDINFLAHEPIINKFRDYKVFLRKLNHLKAKKEKKLYENKPVYSLDTIVKERFPTFGSALRDMDDALSLCFTFAMLPHCRKLTAEFMHYVIESQSLRNTFISIKGIYYQAEVHGEITWVVP--HERGLPHVTDVDFTVLVTFVEFYIAMLGFVNFKLYGLFYPPQIFYLNRECPKEALTFIIRNGGNISHHVVDRPYVQPQWVFDCLNALPPHFSPFMISKKHQRVYHSMRNRND Canalb1 TGNAKNFITRTQAIKKLQISLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPVTFYYSKDIQYLLHEPVLDKFRQHKTFAKKLQKALGRGEYKLDQHRPKYTLNHIIKERYPTFADALRDLDDPLNMLFLFANMPAAEKLCNQWLAYVAKERCLKKVFVSIKGVYYQATVKGQIRWLIP--YKFPTNIPTDVDFRIMLTFLEFYSTLVHFVLYKLYGLIYPPIIFYIGREVPLDILEFCILSCGNITHQIIDRPYVQPQWVFDSINTLPPHLSPWMMSNKQKKLFKKMKKENR Cangl RGNAKNFITRSQAVRKLQISLADFRRLCIFKGIYPREPKNKKKAN-KGSTAPTTFYYAKDIQYLMHEPVLAKFREHKTFARKLTRALGRGEKKLEENRSTYKLDHIIKERYPSFPDAVRDIDDALNMLFLFANLPAAQVICNQWLAYVAKERLIRKVFVSIKGIYYQANVKGEVRWVIP--FKFPENIPSDIDFRIMMTFLEFYSTLLHFVLFKLYGLVYPPKIFYVGREVPIEAIEFLILSCGKVTHQIVDRPYIQPQWVFDCINSLPPHLSPWMMSNKQRKLYKKMQKEDK Capow SGAAINFISRNAALKKLQLKLADFRRLCILKGVYPREPRNKKKASGTGSTANKTYYLAKDIAFLAHEPILNKFREFKVFVRKLRKAIGRKEDRVKAAKPVYTLDHIVRERYPSFVDALRDLDDALCMVFLFARMPRCNRLAHEFESYIVRSRSLRKVFLSIKGIYYQAEVMGALTWLVP--HQFSQKIPADVDFRIMLTFLEFHMTLLGFVNFRLYNVSYPPRLFYVSREVPRGVVELIIRSFGGITHQIVDRPYVQPQWIFDCVNALPPHLSPFLMPKKHRRLYNRIKKQEE Catan2 TGAVTNYISRRQALKKLQISLKDFRRLCILKGIYPRDPPNKKKLN-KGSSAPNTWYFRRDVQYLLHEPLLQKFRDWKIFARKMAKAMGKRNEALDENRPEFSLDHIIRERYPTFNEALRDLDDALSMIFLFASMRSVYRKSIEFTQYVMQTRSLRKTFISIKGIYYQAEIKGQITWVTP--HQFSQQPPSDVDFKVMGTFLQLYDTLLGFILYKLYGLKYPPALFYLSREVPRSAVEFLVRSFGRITHHIVDRPFVQPQWVFDCVNSLPPHLSPFLMSKRNKHLFQKLDQKAE Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SGAAKNYITRTRAVKKLQISLPDFRRLCIFKGIYPREPRNKKKVS-RGSTAATTFYYTKDIQYLLHEPLLAKFREHKAVAKKIGRALGRGESRLEKN-PKVKLDHIIKERYPTFVDALRDLDDALSMLFLFANLPSCQRLTREFEHYVITSHSLRKSFLSIKGIYYQATIQGQILWLVP--YRFVQRTGGDIDFRIMGTFVEFYTTLLGFVNYRLYGLVYPPKFFYLSRETPRAPLEFILKAFGNITHQIVDRPYVQPQWVWDCINDLPPHLSPWMLSNKKRKLLKRIKRDNE Coere1 EGASRTYTTRNRALKKLQLSLADFRRLCILKGIYPVEPRSAKRAN-RGSTKPTTFYYTQDVKLLSSEPLIAKFRHHKIFLRRLQHALGKKDKSLNSHRPEYTLNHLVIERYPSFTDALRDLDDALCMVFLFASMPSCKRLAAEFMHYVIFTHSLRKVFLSIKGIYYQAEIQGQVTWIVP--YQFSQRTPDDVDFKVMATFLHFYRTLLGFVNYRLFNLSYPPKLFFLSREVPRYSLEFIIRAFGAISIQIVDRPYVQPQWIYDSINQLPPHLSPFMLSRKKRRVVNRAKQSKD Conco1 AGAATMYISRNKAIRKLQLKLKDFRRLCIIKGIYPREPKNRKKAA-QGSTNSTTFYYAKDIQYLSHEPLIKKLRDAKSLAKRIHRANIVRDKSLREALPDYNLDHVILERYPSFTDALRDMDDCLNMVFLFATIPPCQLLSREFQHYVMHTNSLRKVFLSVKGIYYQAEIKGEITWLVP--YQFSQRVPTHVDYTVMLNFLEFYVELLRFVNFKLYQLPYPPKVFYLSREVPRNSLLFSIQSLSRITFQITDRPYVQPQWVYDSINALPVHLSPFMLNNKRRKAYDGLKQEDK Conpu1 SGAAKAYVTRSSAVKKLQCSLADFRRLCILKGIFPREPKNKKRAN-KGSTAPKTFYYSKDIAYLAHEPVLKKLREHKAFAKKISRALGRGEKSLEENKPTYRLDHIVKERYPTFIDALRDIDDALCMIFLFASLPSCTRLAAEWQLYIMRSQALRKVFLSIKGIYYQAEVMGQITWLVP--YQFTQSIPTEVDVRVMLTFLELYQTLLGFVFFRLYGLSYPPALFFLSRETSRSVFEFLVRSFGAITHVIIDRPYVQPQWVVDCINTLPPHLSPFMMSNRQKKLYERMNRAAQ Copci AGAAKNYITRTAAVRKLQCSLADFRRLCILKGIFPREPNNRKKAN-KGSSAPTSFYYAKDIAYLAHEPVLKRLREHKAFAKKLSRALGRGEKSLEENKPIYRLDHIIKERYPTFVDALRDIDDALCMVFLFATLPSCARLSMQWQLYVMHTNSLRKVFLSIKGVYYQAEVMDQITWLVP--YQFTQNIPTDVDVRVMLTFLELYQTLLGFVFFKLYNLVYPPPLFWLSRETSRSIFEFIIRSHGSITHVIIDRPYVQPQWVVDSINLLPPHLSPFMMSNKQRKLYEKMKKAAE Croqu1 SGAAKNYVTRNQALKKLQCTLSDFRRLCILKGIYPREPRNRKKAN-KGSTAPASFYYAKDIAYLLHEPVLDKLREHKAFAKKLSRALGRGQKNIEENHEGYRIDHIIKERYPVFGDSIRDLDDALSLIILFSNLPACARLAAEWQIYVMRTKSLRKVFLSIKGIYYQAEVEGQVTWLVP--YAFTQRVPTDVDFRIMLTFLELYQTLLGFVFYRLFNLIYPPKLFFLSREVTRSMLEFVVRSFGRITHHIIDRPFVQPQWVVDCVNILPPHLSPFMLTGKQKKLYQKMKRAEE CryneH991 SGAAKNYVTRNQALKKLQISLSDFRRLCILKGIYPREPLNKKRAN-KGSSAPASFYYHKDIQYLLHEPLLIKFREHKAFAKKLARAIGRQEKNLEDAKPVARLDHLVRERYPTFTLALQDLQDPLNLVHLFSTLPTCGRLISEWKLWAIRTHSLRKMFLGIKGVYYECEVPGQVRWLEG--FEFQQHVPHDVDFRILLTFLDLYRTMVGFVLFKLYNLVYPPPLFYLSRETSSRTWEFVVRAMGSITHVIIDRPWVQPQWVADCVNLLPPHLSPWMMSNKKAKLYEKMEKAAE Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 SGNAKNFITRTQAVKKLQVSLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPVTFYYTKDIQYLLHEPVLGKFREHKTFAKKLQRALGRGEQKLEGNRPKYTLEHIIKERYPTFLDALRDIDDPLNMLFLFANMPAAEKLTNQWLAYVAKERLIKKVFVSIKGVYYQANVKGQVRWLVP--FKFPTNIPTDVDFRIMLTFLEFYSTLLHFVLFRLYNLIYPPTIFYVGREVPLDILEFCILSCGNITHQIVDRPYVQPQWVFDCLNTLPPHLSPWMMSNKQRKLYKKMKKEAR Dekbr2 SGNAKNFITRSRAISKLQVSLADFRRLCIFKGIYPRVPRNKKKAN-RGSKASTTFYYTKDIKYLMHEPLINKFREHKTFAKKLSKALGRGEKRLEENRPRYKLDRIIKERYPSFIDALRDLDDALNMLFLFSNMRAATELTNQWMAYIARQGALKKVFVSIKGVYYSANIKGQIIWLVP--FKFPKNIPSDIDFKVMVTFLEFYATLLHFVLYRLYGLVYPPKIFYIGREVPVDILEFVILSAGSVTHQIVDRPYIQPQWVFDSVNTLPPHLSPWMMTKKQRGLYKRMKEEVR Dicdi KGENLKFITRNEAVKKLQISLKIFRKLCILKGIHPRDPKKKFKGK------HKTYYYSKDIKYLQNEKVLEIIRARKVFKDREKKLINKKQKNLKENRPMITLDHIIKERYPTFQDALKDLDDCLSLIHLFANMDACERLAREFQYYIIQSKSLRKVFVSVKGVYYQADVMGEITWITP--LNYLSKKEKEVDYGVMISFLEFYQALMKFVNYRLFGLTYPPTIFYISREVPRHMLEFVILSFGSITHQIVDRSYIQPQWVFDSVNIPPAHLSPFMIRKKDKWIYNKVQRATA Dmel SGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQ-KGSSEIKVLYHTKDIRFLLHESIVWTLRDYKIFAKKSNRDRAIKDRNLKRRFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFNLAYPPQFFFINREVPREPLVILIRSFGTITHQIVDRPYIQPQWVFDCVNTLPPHLSPFMVKPRHRNLFRKLTKEKE Enthi APKISKYITRTQAIKRLNCTMEQFRKICILKGVSPRLPS-------KGLTQKKTYYHIDDIKPLVNDKVTLKIKQIRAFKKHIRKLTARKEEQLLKTKPVIDLASTIQERYPTFQDALNELGDCLSMVFMFASYRV------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba LGTASKYISRSRAIKKLQVSLADFRRLCILKGIYPREPENRNKLT-KNKRDFKTFYWVKDIQFLAHEPLINKFREYKIFARRLSRAMAKSQTNLEENRPVFELDHIIKERYPSFVDALRDIDDALCMVFLFANMPSCARLASEFMHFVIRTNALRKTFLSIKGIYYQAELYGQVTWVVP--YQFTQNPPSQIDFRVMRTFLELHVTMLGFINFKLFGLHYPPVVFFLSREVPREALEFVIRACGSITHHIVDRPYIQPQWVFDSINSLPAHLSPFVMDKRPRNLLRVIRREAE Fomme1 AGAAKAYVTRSAAIKKLQCSLADFRRLCILKGIFPRDPKNKKKAN-RGSSAPTSFYYAKDIAYLAHEPVLEKLREHKAFAKKLSRALGRGEKSLEENKPVYRLDHIIKERYPTFIDAVRDIDDALCLISLFASLPSCARLSAEWQLYVMRTNTLRKIFLSIKGVYFQAEVMDQVTWLVP--YQFTQNIPADVDVRVMLTFLELYQTLLGFVFFKLYGLVYPPPLFFLSRETSRPLFEFIIRSFGSITHVIIDRPYVQPQWVVDCVNTLPPHLSPFMMSRKQRKLYDKMKRNEE Fusgr1 AGASKNYVTRNQAIRKLQISLPDFRKLCIWKGIYPREPRSRKKVS-KSSTSSTTFYYTKDIQYLLHEPLLQKFRDQKVLEKKISRALGRGDARLEGNKPRYTLDHVIRERYPTFIDAIRDLDDCLSMLFLFANLPSCERLCLEFQHYLIVSKSVTKSFLSIKGIYYQANIQGEVLWLVP--YKFNQRVVGDVDFRIMGTFIEFYMTLLGFVNFRLYGLKYPPKFVYLSRETPRQPLEFLLKSFGNITHQIVDRPYIQPQWVWDSVNALPPHLSPFMLSKKKRKLYEQMKKSAE Galma1 AGAAKNYTTRSAAVKKLQCSLADFRRLCILKGIFPREPRSRKKAN-KGSSAPTSFYYTKDIAYLAHEPILKKLREHKAFAKKLSRALGRGEKSLEENKPIYRLDHIIKERYATFVDAIRDIDDALCMVFLFASLPSCARLAAEWQLFVMHSRALRKVFLSIKGVYYQAEIMDQVTWLVP--YLFTQNVPADVDVRVMLTFLELYQTLLSFVFFKLYGLVYPPPMFFLSRETPRSIFEFLVRSFGSITHVIIDRPYVQPQWVVDCINTLPPHLSPFMMSNKQRKLYEKMKKQTE Ganpr1 RGAASNFISRTRAVKKLQVSLADFRKLCILKGVYPRAVPTAALKR-MGSTAPRTYYYTKDIQYLLHEPLVAQFRRNKVYIRKIRQAANKGEASLEREMQEIGIEHIIKERYPTFSQALHDLPDALTLLHTFLRLPSVRRLCAEWQYVTARRGMLKRSFVSVKGVYYGVELGGGVVWVVP--HEFNVGIPATVDIRILLTFLQLYTTLVRFVNHKLFNLTYPPRLVFLSRETPVAPLLYLLRANGPITHHVTDRPYVQPQWVFDSVNVLPPHRSPWMMSKRDKRLYERMKKKEE Gloin1 AGAAVNYINRNKALKKLQISLADFRRLCILKGIYPREPKNKKKAN-KGSTAPTTFYYTKDIQYLAHEPVLQKFREHKIFLRKLNKAIGKREKNLEQNRPIYTLDHILKERYPTFTDALRDIDDALCMLFLFSTFPACQRICVEFQHYIIHTRSLRKVFLSIKGIYYQTEIKGQITWLVP--YQFSQQVPDDVDFRVMLTFLEFYQTHLGFVNFKLYNLVYPPKVFYLSREVPRYSLEFIIRAFGRITHHIVDRPYVQPQWVYDCVNTLPPHLSPFMMTKKQKTLYNKIRQQEK Hisca1 SGQAKNFITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKAS-KAATPSTTFYYTRDIQYLLHEPLLKKFREQKALSKKIARALGRGEARLEKN-PKLSLDHIIKERYPTFIDALRDLDDALSLLFLFANLPSCQRLCHEFQHYLIATNSLRKSFLSIKGIYYQATILGQIMWLVP--YRFVQRVTGDVDYRIMGTFVEFYTTLLGFVNYKLYGLVYPPKFFYISREAPRAPLEFLLRSFGRITHQIVDRPYIQPQWVWDCINTLPPHLSPWMMSRKKRKLLDKMKQDAE Klula1 RGNARNFITRSQAVRKLQISLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPTTFYYYKDIQYLMHEPVLAKFREHKTFAKKLTKALGRGEKRLEENRPNYQLDNIIKERYPSFADALRDVDDALNMLFLFANLPAAQQMCDQWSAYIAKERCVRKVFVSIKGVYYQASVKGEVRWLVP--YKFPENIPSDVDFRIMLTFLEFYSTLLHFVLFKLYGLVYPPKLFYVGREVPLDIVEFLILSCGKVTHQIVDRPYVQPQWIFDSINPLPPHLSPWMMSNKQRKLYKKMKKDEK Lacbi2 AGAAKNYVTRTSAIKKLQCSLADFRRLCILKGIFPREPRSRKRAN-KGSSAPTSFYYAKDIAYLAHEPVLKKLREHKAFAKKLSRALGRGEKNLEENKPIYRLDHIIKERYPTFIDAVRDIDDALCMVFLFASLPTCSRLAAEWQLYIMRSQSLRKVFLSIKGVYYQAEIMDQVTWLVP--YQFTQNIPADVDVRVMLTFLELYQTLLGFILFKLYGLVYPPPLFFLSREVSRPIFEFMVRSFGTITHVIIDRPYVQPQWIVDCINTLPPHLSPFMMSNKQKKLYEKMKKEIE Lenti61 AGAAKAYMTRSAAVKKLQCSLADFRRLCILKGIFPREPRNRKKAN-KGSSAPTNFYYTKDIAYLAHEPVLRKLREHKAFAKKLARALGRGEKSLEENKPVYRLDHIIKERYPTFVDAVRDIDDALCMIFLFATLPSCARLAAEWQLYVMHTHALRKVFLSIKGVYYQAEVFDQVTWLVP--YQFTQTIPADVDVRVMLTFLELYQTLLGFVFFKLYGLVYPPPIFWLSRETSRPIFEFIVRSFGSITHVIIDRPYVQPQWVVDSVNTLPPHLSPFMMSNKQRKLYERMKRAAE Malgl1 SGAAKNYITRNQSLKKLQITLAEFRRLCILKGIFPRQPRHVKRAN-KGSTAPTTFYYTKDIAYLQHEPVLQAFRDHKAFAKKVNRAIARREKNLDENRPKYRLDHIIKERYPTFVDSLRDLDDALSTLFLFANIPSCARLCAEWQLYVMRTHCLSKVFLSIKGIYFQAVVHGQITWLVP--YMFTQTIPTDVDFRVMMTFLELYQTLMGFVLFKLYNLVYPPKLFYISREVPRTVFEFILRSFGRVTHHILDRPYIQPQWVVDCVNTLPPHLSPFLLSNKQRKLYTRMKKKEE Mellp23 SGAAKNYVTRNQALKKLQCTLANFRRLCILKGIYPRQPRNRKKAN-KGSTASVSFYYSKDIAYLLHEPVLEKLRQHKAFAKKLSRALGRKQKNIESTHESYRIDHIIKERYPTFADSIRDLDDALSLIILFSNLPSCTRLAAEWQTYIIRTKSLRKVFLSIKGIYYQAQIEGQVTWLVP--YAFTQRVPSDIDFRIMLTFLELYQTLLGFVFFKLFNLLYPPKLFFISREVTRPMLEFVIRSFGRITHHIIDRPFVQPQWVVDCINILPPHLSPFMLTGKQRKLYTKMRRAEE Mnele KGSATNYITRTQAVKKLQLTLPDFRKICILKGIYPHEPKKKRKLA-KGSSAPKTFYYVKDIQYLAHEPLLQKFAETKIFVKKVKKALGRDEQRVRDQKPHYTLDHIVKERYPNFADAIKDLDDALCLIFLFSTMPRCRILAVEFMHYVIAAKCIKKVFVSIKGIYFQVEIEGNISWIIP--HQFTTPPPSNIDFKVMLSFLELYTTVLGFVNFKLYNLIYPPKAFFLGREVPREVLVLAIRSLGDITHQIVDRPYVQPQWIFDSINLLPPHLSPFAMPKKRKALYNKMKKASV Monbr EGTATEYMSRSRAVRKLQLSLADFRRLCILKGIYPREPPNKKKVT--GSTANRTYYFVKDINWLLHEPLLQRFRELKTYARRLKKAEAKDQKAIRRREPKVKVNHLVKERYPSFVDAIRDLDDCLCMLFLFASFPQCRRLCNEFMLYVVRARALRKVFLSIKGIYYQAEIMGQVTWIAP--YQFATDVPTDVDFRVMGTFLQFYLTLLGFVNFKLYGMHYPPQFFFLSREVPRYSLEFVIRSFGRITHHIVDRPYVQPQWVYDCINVLPPHLSPFMMSKRDRTLYNRIQKQVE Morel2 AGAAINYITRNQALKKLQVTLADFRRLCILKGIYPREPKNKKKAN-KGSTAPSTFYYAKDIQYLMHEPILGKFREYKTFAKKMAKVMSKGQKTLAENKPIYTLDHIIKERYPTFTDALRDLDDALCMIFLFATMPKCQRLAAEFQHYILHTRSLRKTFLSIKGIYYQAEIKGQVTWLVP--YQFSQDVPTDVDFRVMLTFLEFHQTLCGFVNYRLYNLVYPPTLIFLSREVPRYSLEFVLRALGRITHQISDRPYVQPQWAYDCINTLPPHLSPFMMTNKQQKLYTKIKKAAE Mucci2 KGAAANFITRQQALNKLQISLADFRRLCILKGIYPREPKNKKKAN-KGSTAPATFYYVKDIKYLLHEPLLAKFREYKAFAKKLNKVLHKGEKSLEENKPVYSLDHIVKERYPSFIDALRDLDDALSMLYLFSKLPACQKLISEFQAYVMKSKSLRKVFFSIKGIYYQAEIKGQITWIVP--YQFSQEIPTDVDFRVMLTFLEFYQTLVGFVNFKLYNMTYPPKIFYLSRETPRYALEFMIKSCGSITYQITDRPYVQPQWIADCINTLPPHLSPFMMTNKQRKLYTKMQKADQ Mydma QNAHKIYKKRNEAAKSIQSAIKKLKRLCILKGIYPREPRNRKKVG-KGSTAYKTYYYVKDIQFLAHEPVLNKFREFKVFVRKLKRAIGRQEDHLEENKPTYTLDHIVKERYPTFIDALRDLDGALSMIFLFARLPQCKRLSVEFQHYIISSRSLRKVFISIKGIYFQAEIQRQVTWVTP--HSFTQELPDDVDFRIMLTFIEFYTTMLGFVNFQLYNLQYPPQFVYLSREVPRDALVFILRSFGSITHQIIDRPYLQPQWVFDCVNLLPPHLSPFMLPRKKKALYEKIRKASQ Neucr2 AGAAKNYITRTQAVKKLQLSLPDFRKLCIWKGIYPREPRNKKKVS-KSATASTTFYYTKDIQYLLHEPLLQKFRDQKVLEKKISRALGRGDARFERHKPRYTLNHVIRERYPTFNDALRDLDDCLSMLFLFANLPSCERLCLEFQHYLIVSHSLRKSFLSIKGIYYQANIQGEILWLVP--YKFNQRIVGDVDFRIMGTFVEFYMTLLGFVNYRLYGLKYPPKFFYLSRETPRQPLEFILRAFGSITHHIIDRPYVQPQWVWDCVNALPPHLSPFMLSKKKRKLFEQMKKSAQ Orpsp11 RGAAANYITRNRAVKKLQISLADFRRLCILKGIYPREPKNKKKVN-KGSTAPRTFYYVKDIKYLAHEPILEKFREYKTFAKKLKKALGKKEKSLEENKPEYTLDHLVKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SGAAKNYITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKAS-KTSTPNTTFYYTKDIQYLLHEPLLNKFRDQKSLAKKIARSLGRGESRLEKN-PRLTLDHVIKERYPTFIDALRDLDDALSLLFLFATLPSCQRLCHEFQHYLIMTNSLRRSFLSIKGIYYQATIQGQIMWLVP--YRFVQRVNGDVDYRIMATFVEFYTTLLGFVNFRLYGLRYPPKFFYISREAPKAPLEFILRSFGRITHQIVDRPYIQPQWVWDCINTLPPHLSPWMMSRKKRKLLEKMKTADE Phybl2 KGAAANFITRQRALNKLQISLADFRRLCILKGIYPRDPKNKKKAN-KGSTAPATFYYIKDIQYLLHEPLLQKFRDYKAFAKKLNRVLHKGEKSLEENKPVYNLDHIVKERYPSFIDALRDLDDALSMLFLFSKMPACQKLIAEFQAYVMKAKCLRKVFFSIKGIYYQAEIKGQITWIVP--YQFSQAVPTDVDFRVMLTFLEFYTTLTGFVNYRLYNIAYPPNLFFISRETPRYALEFMIRSCGRITHQISDRPYVQPQWIADCINVLPPHLSPFMMTNKQRKLYQKMKKVAE Picst3 SGNAKNFITRTQAVKKLQVSLSDFRRLCIFKGIYPREPRNKKKAN-KGSTAPVTFYYAKDIQYLLHEPVLAKFREHKTFAKKLQRALGRGEQKLEANRPKYTLEHIIKERYPTFLDALRDIDDPLNMLFLFANMPAAEKLTNQWLAYVAKERLIKKVFVSIKGVYYQANVKGQIRWLVP--FKFPTNIPTDVDFRIMLTFLEFYSTLLHFVLYRLYNLIYPPTIFYVGREVPLDILELCILSCGNITHQIIDRPYIQPQWIFDCINTLPPHLSPWMMTNKQRKLYKKMKKETR Plicr1 SGAAKAYVTRSAAVKKLQCSLADFRRLCILKGIFPREPRHRKKAN-KGSSAPTSFYYAKDIAYLAHEPVLKKLREHKAFAKKLSRALGRGEKSLEDNKPVYRLDHIIKERYPTFIDAVRDIDDALCMIFLFASLPSCARLAAEWQLYVMHTQALRKTFLSIKGVYYQAEVMDQVTWLAP--YQFTQNIPSDVDVRVMLTFLELYQTLLGFVFFKLYGLVYPPPLFFISRETSRPIFEFVIRSFGSITHVIIDRPYVQPQWVVDCINPLPPHLSPFMMSNKQRKLYERMKKAAE Polpo KGENIRFITRNAAARKLQISLKLFRKLCIIKGIHPRDPKKKLQGK------HKTYYYMKDIRFLQHEPIIQTLRDRKTFAKKEKKLRERKDEQFIKNRPSSSIDHIVRERYPTFTDALKDLDDCLTLIHLFASMDSCADLCREFQHYVTVSKSLKKVFVSIKGIYYQAEIMGEITWLTP--INYINKKEKKVDYGVMINFLEFYEVMLKFVNYKLYGLKYPPTIFFCSREVPKHALEFVIQSFGSVTHQIIDRNYIQPQWVFDSVNVPPPHLSPFMIRKKDKWLYQRIAADRN Pucgr2 TGAARNYVTRNQALKKLQCTLSDFRRLCILKGIYPREPRSRKKAN-RGSTAAASFYYQKDIAYLLHEPVLQKLREHKAFAKKLSRALGRKEKNLDSAHDGYRIDHIIKERYPVFTDAIRDLDDALSLIILFANLPSCARLAAEWQIYVMKSRSLKHVFLSIKGIYYQAEIEGQVTWLVP--YAFTQTIPADVDFRIMLTFLELYQTLLGFVFYRLFNLIYPPKLFFLSREVTRPMLEFVIKCSGRITHHVIDRPFVQPQWVVDCINILPPHLSPFLLSSKQRKLYSKMQRAEE Punst1 SGAAKAYVTRSAAIKKLQCSLADFRRLCILKGIFPREPRHRKRAN-KGSSAPTSFYYAKDIAYLAHEPVLRKLREHKAFAKRLSRALGRGEKSLEENKPVYRLDHIIKERYPTFVDAVRDIDDALCMAFLFASLPSCARLAAEWQLYVIHTRALRKTFLSIKGIYYQAEVEGQVTWLVP--YQFTQTIPPDVDARVMLTFLELYQTLLGFVFFKLYGLVYPPPLFWLSRETPRSIFEFIVRSFGSITHVIIDRPYVQPQWVVDCVNTLPPHLSPFLMSNKQRKLYERMKRANE Rhior3 KGAAANFITRQQALNKLQISLADFRRLCILKGIYPREPKNKKKAN-KGSTAPATFYYVKDIKYLLHEPLLVKFREHKAFTKRLNKVLHKGEKSLEENKPVYSLDHIVKERYPSFIDALRDLDDALSMLFLFAMLPACQQLIAEFQAYVVKSKSLRRVFFSIKGIYYQAEIKGQITWVVP--YQFSQNIPTDVDFRVMLTFLEFYRTLVGFVNFKLYNMTYPPKVFFLSRETPRYALEFMIRSCGTIGYQITDRPYVQPQWVADCINELPAHLSPFMMTSKQKKLYTKMQKEDE Rhoto1 AGASKNYITRNQAIKKLQCTLGDFRRLCILKGIYPREPKNRKKAN-KGSSAPASFYYAKDIQYLLHEPVLHKLREHKAFAKKLSKAVGRGEKNLEEQKPTYRLDHIIKERYPTFVDAVRDLDDALSLIVLFAALPACARLAAEWQLYVMRTRSLRKVFLSIKGIYFQAEVQGQVTWLVP--YMFTQHIPSDLDYRIMLTFLELYQTLLGFVFYRLYNLVYPPKLFFLSREVTRPTLEFVIRSFGRITHHVLDRPFVQPQWVVDCINVLPPHLSPFMMTNSQRRLLKKLRSNEE Rozal11 SGAVVNYISRNKAIRKLQITLPEFRRLCILKGIYPREPNNKKKLT-KGSTAPTTFYYLKDIQYLLHEPILQKFREHKIFLRKLNRAIGKGQVRIQEMAPKYTLDHVIRERYPTFIDAVRDLDDALCMIYLFSMFPQCQRLCREFEHYIIKSRSLVHSFVSVKGIYYQAMILGQVTWLVP--FEFSVAVPHDVDFRVMMTFCEFYITLLGFINFKLYNLVYPPQLFFISREAPRLSLEFIIRSFGRITHHIVDRPYVQPQWIYDCINKLPAHLSPFMMNKKDKNLYNSMKRALL Sacce1 RGNARNFITRSQAVRKLQVSLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPTTFYYAKDIQYLMHEPVLAKFREHKTFARKLTRALGRGEKRLEENRDSYTLDHIIKERYPSFPDAIRDIDDALNMLFLFSNLPSAQKICNQWLAYVAKERLVRKVFVSIKGVYYQANIKGEVRWLVP--FKFPENIPSDVDFRIMLTFLEFYSTLLHFVLYKLYGLIYPPKLFYVSREVPIDILEFLILSCGKVTHQIVDRPYIQPQWIFDCINALPPHLSPWMMSNKQKKLYKKMKKEEQ Salro AGTAVQYMTRSAALRKLQLNLADFRRLCILKGIYPRDPANKKKLP--GARAHRTYYFTKDIKYLAHEPLIDKFRELKVFSRKLQKALAKGQKSLREQEPEVKIDHIVRERYPSFVDALRDLDDCLCMIFLFANFPQCRRFSQEFMYYVILTRSLRKVFLSIKGIYYQAEIMGQITWIVP--YKFATEITPDIDLRVMSVFLTFYTKLMGFVNFKLFALEYPPQVFFLSREVPKDALEFAIRSFGRITHHIVDRPYVQPQWVFDCINILPAHLSPFVMSNKRRRLYSKIKKQDR Schco3 AGAAKAYITRSSAVKKLQVSLADFRRLCILKGIFPREPRNKKKAN-KGSSVPTSFYYTKDIAFLAHEPVLKRLREHKAFAKKLSRALGRGEKHLEENKPVYRIDHIIKERYPTFIDALRDIDDALCMIFLFASLPSCSRLAAEWQLYVMHSKSLRKAFLSIKGVYYQAEVMDQITWLVP--YQFTQNVPSDVDVRVMLTFLELYQTMLGFVFFKLYGLVYPPPLFYLSREISRPIFEFLIRSFGAITHVIIDRPYVQPQWVVDCINVLPPHLSPFMMSNKQRKLYEKVKREAE Schpo1 AGAARIYITRNQALKKLQLTLADFRRICILKGVYPREPKNKKKAN-KGSTAPVTFYYTKDIQYLLHEPIVQKFREYKVFARKLSKALGKGEKRLEARKPTYSLDHIIKERYPTFHDALKDIDDALSMLFLFSTMPVCERLCAEFQHYVIRSNSLRKAFLSIKGIYYQAEIFGEITWIVP--YKFAQSVPTDVDFRIMHTFLEFYQALMGFVNFKLYGLRYPPKIFFLSREVPRFSLEFVIRAFGVITHHICDRPYIQPQWVYDSINTLPPHLSPFMMSNKQRKLYSKLKNENY Sorma AGAAKNYITRTQAVKKLQLSLPDFRKLCIWKGIYPREPRNKKKVT-KSVTASTTFYYTKDIQYLLHEPLLQKFRDQKVLEKKISRALGRGDARFERHKPRYTLNHIIRERYPTFNDALRDLDDCLSMLFLFANLPSCERLCLEFQHYLIVSHSLRKSFLSIKGIYYQANIQGEILWLVP--YKFNQRIVGDVDFRIMGTFVEFYMTLLGFVNYRLYGLKYPPKFFYLSRETPRQPLEFILRAFGSITHHIIDRPYVQPQWVWDCVNALPPHLSPFMLSKKKRKLFEQMKKSAQ Sphar RGAATNFISRNQALRKLQLSLPDFRRLCILKGIYPREPSNKKSV--KGNTN-STYYYTKDIKYLLHEPLLLKFREFKTFVKRVNKALGKRDERLEDQKPDYTVDHLVKERYPAFVDSLRDLDDALCMLFLFRVMPRCERVSREFLNYVIESGSLRKCFLSIKGIYYQAEIMGQITWIAP--YNFNQKVPDDVDFRVMLTFLEFYVTMMGFVNYKLYNIRYPPALFFLNREVPTESLEFAIRSMGTITHQIVDRPYVQPQWVYDCINVLPPHLSPFMMSKKHKNLYNKIQKKQK Spipu1 KGAVTNFITRTQAVKKLQISLAHFRRLCILKGIYPREPKNKKKVG-KGSTAPKTYYYRKDIQFLLHEPVLHTLREQKIFARKLSKAIAKREKNLEESKPEYTLDHIIRERYPTFVDALRDLDDALSMVFLFATLPACQRLSAEFQHYVMVSRSLRKVFLSIKGIYYQAEIKGQITWIVP--YQFSQHV---------------------------------------------------LKARASIGSH-------------------------------RRRL--------- Sporo1 AGASKNYITRNQAIKKLQCTLGDFRRLCILKGIYPREPRNRKKAN-KGSSAPASFYYAKDIQYLLHEPVLDKLREHKAFAKKLSKAVGRGEKNLEESKPVYRLDHIIKERYPTFVDSLRDLDDALSLIVLFACLPACARLAAEWQLYVMRTKSLRKVFLSIKGIYFQAEVQGQITWLVP--YMFTQNIPSDLDYRIMLTFLELYQTLLGFVFYKLYNLVYPPKLFYISREVTRPTLEFVIRSFGRITHHILDRPYVQPQWVVDCINVLPPHLSPFMLTGKQKKLYNKMRKAEE Stehi1 AGAAKAYVTRSLAVKKLQCSLADFRRLCILKGIFPREPRSRKKAN-KGSSAPTSFYYAKDIAYLQHEPVLKKLREHKAFAKRLSRALGRGEKSLEDNKPVYRLDHIVKERYPTFVDAVRDIDDALCMIFLFASLPSCSRLAAEWQLYIMRTRSLRKTFLSIKGVYYQAEVMDQVTWLVP--YQFTQNIPADVDVRVMLTFLELYQTLLGFVFFKLYGLVYPPPLFFLSRETSRPIFEFIVRSFGSITHVIIDRPYVQPQWVVDCINTLPPHLSPFMMSNKQRKLYERMKRSAE Tapde11 SGAAKNFISRNMAIKKLQVTLADFRRLCILKGIYPREPRNKKKAN-KGSTAPTTFYYTKDISYLVHEPVLNKFRDHKIFARKLSKALGKQEKKLEENKPTYTLDHIIKERYPTFIDALRDLDDALSMLFLFASMPTCDRLCREFEHYVIRSKALRKVFLSIKGIYYQAEIKGQITWLVP--YKFSQQVPTDVDFRIMLTFLEFHQTYVGFVNYRLYGLVYPPKIFYLSREVPRYSLEFVIKAFGSITHHVCDRPYVQPQWIYDCINILPPHLSPFMMSNKQKKLYAKMAKEDE Thetr DTFARKYFTRTKAMRKLGLSVGNFRRLCILKGVFPRAP--------KGGSSSQVYYLAKDIKFLAHDPLLQSFQKEHRHFKQMKSALGVRDKKLNELRPSISVSHIIRERYPTFVDAIRDLDDALSLMFLFASVERIEFSTLHFLNYVVKTSSLKKVFISIKGIYYQAAIMGQVTWIVP--HRAKVDTELIVNHTILHSFVQFYDTLLKFVNFKLYEMPYPPEVIWLNRETPVDSLQFVVKALKRITHHIIDRPYVQPQWVYDSVNALPPHLSPFMLSKNKRRKYNSVSRKRK Treme1 SGAAKNYITRNQAIKKLQVSLADFRRLCILKGIYPREPLNKKRAN-KGSSAPATFYYHKDIQYLLHEPLLVKFREHKAFAKKLARAVGRQEKNLEDAKPVARLDHLVKERYPTFTLALQDLQDPLNLIHLFSNLPTCGRLCSEWKVWAIKTHSLRKVFLGIKGIYYECLVPGQVRWLEG--YEFQQHVPHDVDFRILLTFIDLYRTLISFVLYKLYNLVYPPPLFYLSREVSQRAWEFVIKALGSITHVVCDRPWVQPQWVADSVNLLPPHLSPWMMTNKKAKLYEKMARAEE Trire2 AGAAKNFITRNQAIKKLQLSLPDFRKLCIWKGIYPREPRSKKKVS-KSSTASTTFYYTKDIQYLLHEPLVQKFRDHKVLEKKISRALGRGDARLESNKPTYTLDHVVRERYPTFVDALRDLDDCLSMLFLFANLPSCERLCLEFQHYLIVSKSLTKSFLSIKGIYYQANIQGEVLWLVP--YKFNQRIVGDVDFRIMGTFIEFYMTLLGFVNFRLYGLKYPPKFVYLSRETPRQPLEFILKSFGSITHQIVDRPYVQPQWVWDSINALPPHLSPFMLSKKKRKLFEQMKKSAE Umbra1 KGAAANFVTRNQALKKLQISLADFRRLCILKGIYPREPRNKKKAN-KGSTAPTTFYYHKDIQYLLHEPVLHKFREYKAFAKKLAKVMAKGQKSLEEHKPVYSLDHIVKERYPTFVDAVRDLDDALSMLFLFATMPVCQRLTAEFQIYVMKSRSLRKVFFSIKGIYYQAEIKGQVTWLVP--YQFAQTIPTDVDFRVMLTFLEFYRTLVGFINFRLFNLIYPPKLIFLSRETPRYALEFIIRSFGKITHQVCDRPYIQPQWVADSINMLPPHLSPFMMSNKQKKLYTKIKKSEE Ustma22 SGAAKNYITRNQAIKKLQVTLADFRRLCILKGIFPRQPKSVRKAN-KGSTAPTTFFFAKDIAYLQHEPVLQSLREHKTFAKKLSRAIGRREKNLDESKPTYRLDHIIKERYPTFRDSLKDIDDALSLLTLFANLPACSRLCAEWQLYVMKTKALKKVFLSIKGIYFQAEVHGEITWLVP--YLFTQHIPSDIDFRIMYTFLELYQTLLGFVLFKLYNLVYPPRFFYISRECPRAVIEFVLRSFGRITHHIIDRPFVQPQYIVDCANTLPPHLSPFMMSNRQRKLYEKLKRAEE Walse1 KGAVKNYMTRNQAIKKLQISLADFRRLCILKGIFPREPRNKKKAN-KGSTAPKAFYYTKDIVYLQHEPLLNSLREYKSFAKKISKAVGRGEKSIEENKPEYRLDHIIRERYPTFQSTLNDLPDAISLIMLFSHLPACAKLSAQWQLYVMRTKSLRKVFLSIKGVYFEAEVEGRIRWLVP--YLFTQHIPEDVDFRILMTFLELYQTLTGFVFYKLYNLVYPPPLFYLSREVTRPTLEFVIRSFGRITHMVVDRPYIQPQWIVDSANTLPPHMSPFMMGSKQRKLYNKVRQTDE Zygro1 SGNARNFITRTQAVKKLQVSLADFRRLCIFKGIYPREPRNKKKAN-KGSTAPTTFYYHKDIQYLMHEPVLAKFREHKTFAKKLTKALGRGQQKLEENRDSYKLDHVIKERYPSFPDAIRDIDDALNMIFLFSNLPAAQAISNQWMAYVAKERALRKVFVSIKGVYYQADIKGEVRWVVP--FKFPENIPRDIDFRIMLTFLEFYSTLLHFVLYKLYGLVYPPKIFYVGREVPIDIAEFLILSCGKVTHQLVDRPYVQPQWIFDCVNPLPPHLSPWMMSNKQRKLYKKMKRDER [Cluster1847.fasta_al_trimmed; alignment length = 155] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ----------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 PAVWARL-PPDLIPLNSSCCCRMSIEIQKCPAC-HRYIGPDCREIGIFNWNNRCLFMHDLLEDYTCSYTTSETPIHSWVLTVSRRYFVGEKRFSAVWFAYARILLAND--MKCLKCGPEPRVTIWDGVTLAFTRKNILPSLRPPTHINAPRRSTT Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster1858.fasta_al_trimmed; alignment length = 158] Allma1 MIIVSEIGDKTFLIAAILAMTHPRAVVFAAALSALAVMSVLSALLGNVLPALLSRTYTAGLLFAVFGVRMFFEARAMEEMAEVAAELSPIFVETFVLTFLAEWGDRSQIATIALGAAGHGTIVGHSLCTGLAVVGGRMLASRISVRVTMAGSFVFICF Ashgo11 MVGVSEIGDKTFLIAALMAMRHPRLLVFSAASTSLALMTVLAGIIGGTFTSLVPQRYTAGILFFIFGYKLALESLETGELAEVEEEISPVWIQTFVMVFLGEFGDRSQISTIAMASSSQGATIGHLICTAVAVIGGKLLAKRISMRVNLGGAISFIIF Aspfu1 MIVVSEIGDKTFLVAALMAMRHPRLLVFSAAFSALIGMTVLSAILGHAVPTLIPKSVTAAVLFIVFGLKMLKEGREMEEMKEVEMELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGAISGHGICTAAAVIGGAAIAGKVSMRVTLGGAAALLIF Aurde31 MIIVSELGDKTFLIAAILAMRHPRLVVFAGAFGSLVVMSILSAALGHILPALIPKKWTAAMLFLIFGAKMLLEARDMQEMREVEEELGPVFIQAFLLTFLGEWGDRSQIATMVLAAAHNGTILGHSLCTALAVIAGKWLASKISVKVTYGGAFLFIFF Batde5 VILVSEIGDKTFLIAAVLAMRNPRLLIFSAAMSALFLMTVISALLGQILPSLLSKQYTAAILFIIFGFRLLHEGYYMEELEEVTQELSPIWIQAFALTFVAEWGDRSQLATVALAGAEDGGLLGHAICSCVAVIGGRMLAARISVKVTMIGALLFIAC Botbo1 MIIFSEIGDKTFLIAAILAMRHPRALVFAGAFGSLVVMSILSAAMGHLLPALIPKQWTAGVLFLVFGVKMVQEGRSMEEMKEVEEEIGPVFVQSFILTFLGEWGDRSQIATIALAAAHNGTIVGHACCTAIAVLGGRWLSNKISVKVTFGGSALFLIF Botci1 MILFSEIGDKTFLIAALMAMKHDRLLVFSAAFSALIAMTILSAVLGHAVPTLIPKRFTAAGLFLIFGGRLLKEGLAMEEMKEVEMELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGAVSGHAVCTGVAVIGGRAIAGKVSLRVTLGGAIAFLIF Caeel VIVVSELGDKTWFIAVIMSMRHSRLTVFSGAMGALALMTVLSACLGWIT-QVIPRAVTSTALFALFGLKMLHEGWTMEGYEEAQAEVSRIFIEAFSLTFVAEWGDRSQLTTIILGARENGGILGHALCTGIAVIGGKIVAQRISVRVTLIGGVVFLLF Canalb1 MIIVSEIGDKTFLIAALMAMRNSRIVVFSAAFSSLVVMTVLSGIVGHALPTLISQRLTASALFIIFGVKLLREGLAMEEMAEVEEEITPVWIQVFVMTFLGEWGDRSQIATIAMAAGSEGAIIGHGLCTAAACIGGKYLAKKISMRVTIGGAIAFFIF Cangl MIGLSEIGDKTFLIAALMAMRHARLLVFTAAAISLTIMTVLSGFLGHTFVSLIPESYTAGILFLVFAYKLLIEGLEMEEMTEVEEEISPIWVSIFLMVFLGELGDRSQISIIAMATDNDGGVMGHCICTGIAVLGGKLLATKISMRITLSSAVLFLIF Capow VIIVSEIGDKTFFIAAIMAMTHPRKVIFIGAIAALALMTVLSVAMGFAT-TIIPRYITSTMLFVFFGLKMLRDGWKMEELEEVTLELPPVMMQAFVLTFLAEWGDRSQITTIILGATEDGGTLGHALCTGLAVLGGQLLAKRISVRVTLIGAVLFLLF Catan2 MVIVSEIGDKTFLVAAILAMTHPRLVVFIAAWSALAVMSVLSALLGNVLPTLLNRTYTAGVLFLVFGFRMVQEGRGMEEMAEVAAEISPIFVETFVLTFLAEWGDRSQIATIAMAAAGNGTIAGHSLCTGLAVMGGKMLATRISVRVTLVGGVTFLAF Cioin VIIVSEIGDKTFFIAAIFAMKHARSTVFAGAIAALGLMTFLSVVMGYAT-TIIPRSYTSVILFVIFGAKMLHEGISMEEMEEVQAELSPVLIQAFTLTFLAEWGDRSQITTIVLAASEDGAVIGHALCTGMAVIGGRMIAQKISVRVTIIGGVFFIFN CocheC53 MIIFSEIGDKTFLVAALMAMRHPRLLVFSAAFSALVVMTVLSAVMGHAVPALLSERFTAAALFLVFGVRLIKEGLAMEEMREVEQELSPAWVQTFVMTFLGEWGDRSQIATVAMAAGSDGAVVGHGLCTAGAVIGGRAIAGRISMRVTLGGAIAFLIF Coere1 MIFVSEIGDKTFLIAAILAMSNPRLTVFLAACSALWIMSILSAFLGHALVTFVPMSWVAAVMFLVFGVKLLQEAREMKEMHSVEAELSPIFVETFVLVFLAEWGDRSQLATIALGAAQNGTILGHTCCTGFAVIGGQLLASRISVKVTCAGGVLFIIY Conco1 IILVSEIGDKTFFIAALLAMKHSPVTVFSGSFLSLALMSVLSAALGHTIFNWLPKQYIASGLFLVFGFKMVYDGYKMAELLETEEELSPIFVQSFVLCFLAEWGDRSQISTITLAATGDGTVLGHSICTAGAVLGGKYLAEKISVKLTILGGATFLVF Conpu1 MIIVSEIGDKTFLIAAILAMRHPRLSVFAGAFGSLLVMSLLSAELGQLLPALIPKRWTAGALFLVFGGKMLLEGKDMEEMREAEEEIGPVFVQAFILTFLGEWGDRSQIATIALGAAHSGTVVGHSCCTALAVVGGRYVSTKISVKVTLGGSVLFLLF Copci MIIASEIGDKTFLIAAILAMRHPRMVVFAGAFGSLVVMSVLSAAMGHLLPTLIPKRWTASILFLVFGVKMFLEARAMEEMKEAEEEIGPVFVQAFVLTFLGEWGDRSQIATIALGAAHNGTVVGHAFCTALAVIGGRYVSTKISVKVTLGGSVLFIIF Croqu1 MIVVSEIGDKTFLLAALLAMRHSRLVIFLGAFSALLVMSILSAGLGHILPTLISRRYTASALFLVFGSKMLHEGLIMEELKEVEDEISPVFVQTFIMTFLAEWGDRSQISTIALGAAHSGTVLGHAFCTFLAVMGGRWLATKISVKVTLGGAVLFLVF CryneH991 MIVVSEIGDKTFLIAAIMATRHPRMTVFAGAFASLVVMSILSAALGRVILGLIPKLWTASVLFFVFGAKMLQEAFSMDEMREVEEELNPVFAQAFVLTFLGEWGDRSQITTIAMAGAHSGTIVGHGICTCGAVLGGRYLSTKISVKISLLGAAAFIIF Crypa2 MILFSEIGDKTFLVAALMAMKHDRVVVFTAAFGALITMTVLSAVLGHAVPTLIPKKVTASALFLVFGARMLKEGLAMAEMAEVEMELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGAVLGHACCTGVAVLGGRAIAGRVSLRVTIGGAVAFLVF Debha1 MIIVSEIGDKTFLIAALMAMRNSRFIVFSAAFSSLAVMTVLSGIVGHALPALISQRLTASILFIVFGLKLLKEGLEMEELAEVEEEISPVWIQVFVMTFLGEWGDRSQIATIAMAAGSDGAIIGHGVCTAAACVGGKLLATRISMRVTLGGAIAFFVF Dekbr2 MIAVSEIGDKTFLVATIMAMRYPRALVFSSSFAALGLMTALSGLLGHTLPTLLSTRVTAAFLFLVFGTKLLRECLATNEMNEVEEEISPTWIQIFVMTFLGEWGDRSQIATIALAAGSDGGILGHAACSGIAVVGGKYLASKISVRILMGGTIAFYIF Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel VILLTELGDKTFFIAAIMAMRHPRLIVFGGAIAALALMTVLSCAFGMAA-NFIPKIYTSTALFLIFGLKMLYDGYKMEELEEVQTDLMRILAQAFTMTFLAEWGDRSQLTTIILAASKDGGIIGHCICTGLAVIGGRLVASKISVRVTIVGGIVFIGF Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 MIIASEIGDKTFLIAAILAMRHPRAVVFSGAFGALAVMSVLSAALGHVLPTLIPKSWTASVLFFVFGAKMLQEGREMEEMREAEEEIGPVFVQAFALTFLGEWGDRSQIATIALGAAHNGTTIGHACCTAFAVIGGRYISTKISVKVTLGGAVLFLLF Fusgr1 MILVSEVGDKTFLVAALMAMKHDRMVVFTAAFGALLVMTVLSAVLGHAVPALIPKRVTAAGLFFVFGAKLMREGMQMAEMHEVEQELSPAWVQTFIMTFLGEWGDRSQIATIAMAAGQDGATCGHAICTGVAVIGGRAIAGRVSLKVTVGGATAFLVF Galma1 MIIFSEIGDKTFLIAAILAMRHPRMLVFLGAFGSLVVMSFLSAAMGHILPTLIPRSWTAAVLFLVFGAKMFMEAREMEEMREAEEEIGPVFVQAFILTFLGEWGDRSQIATIALGAAHNGTVVGHSCCTALAVVGGRYVSSKISVKVTYGGSVLFLLF Ganpr1 VILVSEIGDKTFLINCVMAMRNPRLVVFSAAMSALALMSVLSAALGVALPALLSRRVTAALLFLVFGVKMIKEARDMQELQEVTQELSPVFVQTFALTFLAEWGDRSQISTIVLAAAKNGAVMGHSICTGGAVMGGKLIASRISVKVTYVGAALFIAF Gloin1 MIGVSELGDKTFFIAAIMAMKNSRFIVFSAAFCSLILMSVLSAALGYALPNLIPREYMASLLFLCFGIKMGFEGYNMHEMEEISEELSPVFVQTFILTFLAEWGDRSQIATIALAAAQNGVIIGHGFCTCLAVVGGKFLAAKISVKVTIIGSILFIAF Hisca1 MILVSEVGDKTFLVAALMAMRHPRMIVFSAAFTALIAMTVLSAILGHAVPTFISKSFTAATLFLIFGLKMAVEAKKMEEMKEVEMELSPAWVQTFVMTFLGEWGDRSQFATIAMAAGQDGAVTGHGICTTAAVMGGRAIAGRVSMRVTFGGAVAFLIF Klula1 MIGVSEIGDKTFLIAALMAMRHDRLLVFSASTASLVIMTILGGLIGRTFTTLIPYKYTAGILFLVFGYKLVLEGLEMEELAEVEEEISGTWIQIFTMVFLGEFGDRSQISTIAMASGSNGACIGHAICTGVAVIGGKLLASKISMRVTLGGALSFFIF Lacbi2 MILVSEIGDKTFLIAAILAMRHPRMLVFAGAFGSLVVMSILSAAMGHLLPTLIPRKWTASVLFLVFGAKMFMEARGMEEMREAEEEIGPVFVQAFVLTFLGEWGDRSQIATIALGAAHNGTVVGHSCCTALAVIGGRYVSTKISVKVTFGGSILFLIF Lenti61 MIIVSEIGDKTFLIAAILAMRHPRLVVFAGAFGSLVVMSILSAELGHLLPTLIPRKWTAALLFLIFGVKMLQEGREMEEMKEAEEDIGPVFVQAFVLTFLGEWGDRSQISTIALAAADNGTVVGHSCCTALAVMGGRYVSTKISVKVTLAASALFLLF Malgl1 -------------------------------------MSTLSSFMGAILPALLTRRAASAILFIVFGVIALRQGLAMKEWKETQEEISPVFSQAFILSFLGEWGDRSQITTMALASTHRGTSLAHMACIMLAVMAGAIFATRISPRLTIGGAMIFLVF Mellp23 MIVVSEIGDKTFLLAALLAMRHSRSVIFLGAFSALLVMSILSAGLGHILPTLISRRYTASGLFLVFGVKMLHEGLVMEEMKEVEDEISPVFVQTFIMTFLAEWGDRSQISTIALGAAHSGTVLGHAFCTFLAVMGGRWLATKISVKVTLGGAILFLVF Mnele VIIVSEIGDKTFFIAAIMAMKHPRMLIFSAAIGALIVMTILSVVLGFLT-TVIPQIYTATFLFVLFGLRMLYEGYYMEELEEVQMELSPIFVTAFTMTFLAEWGDRSQITTIILSSREDGGCFGHSLCTAGAVIGGRMIAQRISVRVTLIGGVVFLMF Monbr MMVVSELGDKTFFIAAILAMRHSRFTIFCGAIGALGLMTFLSAYVGALA-TVIPRIYTATGLFVIFGLRLLRDGYNMEELEEVQQELSPVLVQSFIMTFLAEWGDRSQIATIILGAREDGGILGHSICTFIAVMGGRFMAQRISVRVTIAGGVVFLIF Morel2 MIVVSEIGDKTFLIAAIMAMKHPRLLVFSAAISALAVMTFLSAAFGHAVPNLIPRTYTAAILFFCFGIRMFYDGYHMHELEEVTQELSPVFVQTFVMTFLAEWGDRSQIATIALAAAHNGGVFGHSLCTGVAVIGGRMLASRISVRVTLAGAVVFEIF Mucci2 MIIVSEIGDKTFLIAAIMAMKHSRLVVFSAAFSSLLIMSVLSAFLGHVVPNLIPKEYTAALLFLCFGLRMMYEAYHMEEMNEVEEELSPVFVQTFVLTFLGEWGDRSQISTIALAAANNGVVIGHGMCTALAVIGGRMLASKISVRVTFAGAILFLIF Mydma VIIVSELGDKTFFIAAIMAMRHSRLIIFTGAIAALSLMTILSVFLGYAT-TVIPRKYTSTALFAFFGLKMLKEGYHMEELEEVSAELSPILIQSFTMTFLAEWGDRSQLTTIILGSRENGGVIGHSLCTGLAVLGGRLIAQRISIRVTLVGGALFLCF Neucr2 MILFSEIGDKTFLVAALMAMKHDRLVVFSGAFAALITMTILSAVLGHAVPTLIPKKITAAALFLVFGARLLREGMAMAEMQEVEQELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGAVVGHGICTSVAVIGGKAIAGKVSLKITVGGAVAFLVF Orpsp11 MIMVSEMGDRTFLSNCVMAMKHDRKLVFFSAMAALALMAILSAILGYTLPALLSKKYTAIILFIIFGVKMLLEAKEMEELEEVNKQLSPTFVQIFTITFLAEWGDRSQIGTIILAASSDGTIIGHGICTALAVICGKLLAQKISVKVTFVGGCLFLLF Pench1 MILVSEIGDKTFLVAALMAMRHPRLVVFSAAFSALILMTVLSAVLGHAVPTLIPKTFTAAILFLIFGVKMLKEGREMEEMREVEAELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGASAGHGICTAAAVIGGRAIAGRVSMRVTLGGAVAFLVF Phybl2 MIIVSEIGDKTFLIAAIMAMKHPRIVVFAAAFCSLALMSVLSALLGHVLPNLIPKQYTAALLFLGFGIRMMYEGYYMDEMSEVEQELSPVFVQTFVLTFLGEWGDRSQISTIALAAANNGVIIGHTLCSAMAVMGGRMLASKISVRVTFAGSVLFIIF Picst3 MIIVSEIGDKTFLIAALMAMRNSRLVVFSAAFASLVVMTVLSGIVGHALPSLISRRLTASILFLVFGAKLLNEGLAMEELQEVEDEISPIWIQVFVMTFLGEWGDRSQIATIAMAAGSDGAIVGHGLCTAAACIGGKLLAKKISMRVTLGGAAAFFVF Plicr1 MIIFSEIGDKTFLIAAILAMRHPRVVVFAGAFGSLVLMSILSAAMGHLLPALIPKHWTAAGLFLVFGTKMLLEGRAMEEMREAEEEIGPVFVQAFILTFLGEWGDRSQIATIALGAAHNGTVIGHSCCTALAVIGGRYVSTKISVKVTLGGAVLFLLF Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 MIIVSEIGDKTFLLAALLAMQHPRLIVFTGAFLALLVMSVLSAGLGHVLPTLISRRYTASALFLVFGLKMIREGMEMEEIEELEHEISPVLIQTFIMTFLAEWGDRSQISTIALAAAHNGTVLGHAICTFFAVMGGRWLATKISVKVTLGGAILFLIF Punst1 MIIFSEIGDKTFLIAAILAMRHPRMAVFAGAFLSLALMSVLSAALGHILPTLVPKAWTAAALFFVFGWKMLKEGREMEEMREAEEEIGPVLVQAFVLTFLGEWGDRSQIATIALGAAHNGTIVGHSCCTALAVLGGRYVSTKISVKVTLGGAVLFLLF Rhior3 MIIVSEIGDKTFLIAAIMAMKHSRLVVFSAAFSSLAIMSILSAFLGHVVPNLIPKQYTASVLFLCFGARMLYEAYHMEEMAEVEEELSPVFVQTFVLTFLGEWGDRSQISTIALAAANNGVVIGHGLCTAGAVIGGRMLATKISVRVTFAGAILFLLF Rhoto1 VILTSEIGDRTFLIAAILSMHHPRITIFAAALSALGVMSFLSALLGNILPNLLPKRYTAAILFFVFGAKMLREGLEMEEMREVQKEVSPIFIQAFILTFLAEWGDRSQITTIALGAAHNGTTLGHSVCTGGAVLGGRWISQHISIKVTLGGAVLFLIF Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 MIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSERYTAGILFLVFGYKLTMEGLEMEEMAEVEEEISPVWVQIFLMVFLGELGDRSQISIIAMATDSDGAVIGHAICSGLAVVGGKLLATRISIRITLASSLLFFIF Salro MMIVSEIGDKTFFIAAIMAMRHPRFIVLAGAAVALIIMTVLSAYIGSLA-TIIPRHYTATLLFVFFGLRLLKEGYSMEELEEVTQELSPVFVQAFVLTFLAEWGDRSQIATIILGARENGASLGHVLCTFIAVVGGRLLAQRISVRVTLIGGVVFLLF Schco3 MIIFSEIGDKTFLIAAILAMRHPRMTVFLGAFGSLFVMSLLSAALGHILPTLLPKHYTAAILFFVFGAKMLMEAKNMEEMREAEEEIGPVFVQAFILTFLGEWGDRSQIATVALGAAHNGTVLGHSCCTALAVIGGRWISTKISVKITLGGAVLFLLF Schpo1 MIFGCEIGDKTFIVAALLAFENSRLTVFAGSYSALFIMTLLGVLLGHAAPLLFPRKLTGGVLFVIFGIKMLMEAKEVDEFQNVRNEISPLFIKAFALTFVSEWGDRSQIATIAMAASDNGANVGHACCTALAVISGKYISTKIKVHVMFIGGILFIAF Sorma MILFSEIGDKTFLVAALMAMKHDRLVVFSGAFAALITMTILSAVLGHAVPTLIPKKITAAGLFLIFGARLLREGMAMAEMQEVEQELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGAVVGHGICTSVAVIGGKAIAGKVSLKVTVGGAVAFLVF Sphar -------------------------------------MTVLSAGMGWVI-TIIPRIYTSTLLFFVFGVKLIRDGSRMEEFDEVTQEL----MQAFTMTFLAEWGDRSQITTVVLAARENGGTIGHAVCTSLAVVGGRMVAQKISVKVTIAGGIVFLIF Spipu1 VILLSEIGDKTFFIAAILAMKNSRFLIFSAAMSALTVMTVLSAFLGHIAPLLISKRYTAAVLFLVFGVRMLRDGWRMEELREVAAELSPIWVEGFVLTFLAEWGDRSQIATVALAGAEDGSLAGHAICSSVAVMGGRMLAARISVKVTLIGGLLFIVF Sporo1 VILVSEIGDRTFIIAAILSMRHSRTVIYAGALSALATMSLLSALLGTIVPSLLPKKWTAAVLFFFFGARMLQEGLEM---------VSPIFVQAFVLTFLAEWGDRSQITTIALAAAHNGTTLGHSVCTLGAVLGGRWISQHISIKVMLSGAVLFLIF Stehi1 MIIFSEIGDKTFLIAAILAMRHPRLTVFAGAFGSLVVMSFLSAIMGHVLPALIPKRWTAAVLFFAFGGKMVLEGRAMEEMREAEEEIGPVFVQAFALTFLGEWGDRSQIATIALAAAHNGTIIGHSCCTALAVIGGRYVSTKISPKVTLGGAFLFLSF Tapde11 MIIISELGDKTFLVAALMAMRHDRLVVFGAAFAALLIMSVLSALLGHTMPQLLPKWLTACGLFFVFGGKMCWEGYNMEEMAEVEQELSPIFVQTFTLTFLGEWGDRSQIATIAMAAGSDGTVVGHGMCTALAVVGGRLLASKISVRVTLGGGCLFILF Thetr MIIVSEIGDKTFFIACILSMRHPRMIIFLAALAALGFMTAISAAMGWVVPLLVPREYTATILFAIFGVRLLKEAHEMDELIEVQDELSPIFAQCFLLTLLAEWGDRSQIATIIMAASRNGGTLGHALCTGVAVVGGQVLSERISVKVSYVGGALFVLF Treme1 MIVVSEIGDKTFLIAAIMATRHPRITVFGGAFASLVVMSILSAALGRVILGFIPKVWTAAILFLVFGIKMLQEGLTMDEMREVEEELNPVFAQAFILTFLGEWGDRSQITTIAMGGAHSGTIVGHGVCTLGAVMGGRYLSTKISVKITLIGAAAFLIF Trire2 MILVSEVGDKTFLVAALMAMKHDRMVVFSAAFGALLVMTVLSAVLGHAVPALIPKRLTAAGLFFVFGARLLREGMQMAELHEVEQELSPAWVQTFVMTFLGEWGDRSQIATIAMAAGQDGALAGHCICTGVAVIGGRAIAGRVSLKVTVGGAVAFLLF Umbra1 MIIVSEVGDKTFLIAAIMAMKHSRLVVFAGAFSSLFVMSVLSAFLGHVVPNLLPAAYTAAVLFFCFGVKMLSEAYKMEEMAEVEEELSPVFVQTFILTFLGEWGDRSQISTIALAAANNGVVVGHSMCTFVAVMGGRYLATKISVKVTYTGAVLFIIF Ustma22 MIIVSEIGDKTFLIAAILAMRQNKVVVFSGAFASLAVMSVLSALLGVMFPSLLPRSVTAAALFLVFGLKMLKDGLGMHEWEEAEREISPVFAQAFVLTFLGEWGDRSQIATIALAAAHNGTILGHACCTSMAVIAGSWLASRISVKVTLGGASLFLLF Walse1 MIVVSELGDKTFLIAAILAMRNPQLVVFSGSFGALSAMSVLSALLGQILPALLPKSYTAAMLFIVFGVKMFNDAKGMEEMQEAIQEISPAFVQAFILTFLGEWGDRSQISTIALAAAHGGTSLGHGMCTALAVLGGRIVASKISIKVTFGGSALFVLF Zygro1 MIGVSEIGDKTFLIAALMAMRHTRWLVFSSAASSLAIMTVLSGLVGHTFVSIISERYTAGMLFLIFGYKLTLEGLEMDELAEVEEEISPIWIQIFSMVFLGEFGDRSQISIIAMASDSNGAVVGHFICTGVAVVGGKFLATKISMRVTLGGAFSFFIF [Cluster1860.fasta_al_trimmed; alignment length = 315] Allma1 LERIAQACQRV--IEDPENIGLVQRVHEYYAKVALVSLLQVYLDVIPGYRIHELTEAQKVSKDVKKLRNFESTLLANYQKYLVALDKKIMAYLAVTAFCKL-LQTHPHFNFRLNILLSKRLTRTIVDTLRDVFRRDVSSEAVRLVAKAIKGGCDPRVNKKQRKSMKRQLEVEKELKESEAVVSLEDRKKHHRVTLEHVFLTYFRVLKLIPAVLEGLSLFAHLISIEFFQSLFAVFKSYLLRIVSTAHRVLSGQLYAVLGDLEVLD-EVPIV--TALFVRLVRVSAVMACLATAATMTAKPYADDPAAAPYDFALL Ashgo11 KELIAELVEKI--IEEPENTSALTRLRKMTSKFSMLALIPVWKSIIPGYRIRPLTEMEKVSKDVARLRNFEEKLVHNYKLYIDHLASLALGNIAATAAVEL-AGSFSHFNFMSEVLVVRRVC-KAIKVLETLMNEDVSAEIVRLLSRTLKVRVDESVSKKQRKVRKEMKEIEEEMRKAEQAVSAEEREKNQAELLKLILALYLNVLKLIGSVLEGLAKFGHMANLELLGDFLTVMKELILLCIVTAFSLVSNHLYSVLPYLKALDHVFQRA--AAFTKRLYICMETVALLKFLDKLMTKMEASTPAATIWENALL Aspfu1 KEELARLATII--NEDPEHISSFKSMADMIQKLALAAQAAVYKDVIPGYRIRPLSEEDKVSKEVRKLRSFEQSLLSGYKHYVQKLLDLTLKSIAINCACNL-LLSVPHFNFRTELLLVNRLAKRCRETVEEVFRKDVSLEAVRLLSKMMKAKVHESVTKRERKLQKERKAVEKDMKEADALVSHEERDKNQAETLKLVFGTYFRILKLMGPVLEGLAKYAHLINQDFFGDLLEALKDLILLCTITAFALLEGQLYRSLYSLRCLQSTLIRL--GSFTKRLMTTSLALATLSLLNQVAKHPFAADVAGTVWEGELL Aurde31 QDQIASLCQEI--VGDPENLALLRRLATFIRKLALLSQMTVFKDIVPGYRIRALTDKEKVSQIVQRTRDFEQGLVIIYQSYLRSLDTELLAPVALQCMCTL-LTDLAHFNFRANLMIVGHLSRKCYKTVVTVFRNDASLELVRLFNRMVKERVHGNISKKERKNLKERKEIEKEMREANAEVDKEERAKTHTETLKLLFALYFRILKLLAPALRGISKFAHLVNIDFFRDLLKVLQEHILQCIVTAFELLSGQLYKLIPTLRALTLALTRT--AAFVKRLLTTSLAQKTLAFVRTLVAQPDLDDPSTSAWECVTL Batde5 REQLAQIASRI--IEDPENIGELKTLQHLSVKFALLTQLAVFKDIIPGYRIRKLTDKESVSQEVKRVRRYEESLIGKYQEYLQLLESLVIPGIALKCLSDL-LKSVPHFNFRLNIMVINSLRKVCCNSIGELLREDASLEAVKLISKLAKQSVRSCVSKKMRKINRAQADVDVELQEAEATIDRSERQKLHSETLKFVFLVYFRILKLVVPALEGLGKFSHLINIDIFNDLVAAIKKICLQCILTVLQLLSSITYAILSKLLVLELMLNRV--ASFLKRLSTTALTIGSLATIHKTLMRPYMDDMATNLWEMSIM Botbo1 KEQLAGLCQEI--IADPESLGLLRRLHTFIRQLAFLSQLAVFKDVIPGYRIRPLTDKEKVSQMVMRTREWEQGLVGVYQSYLKTLESEILTTIAYKCLCSL-LTSVTHFNFRLNIMIVARLSKRCLSSLITVLREDSSLEVVRLLNRMVKERVHPNLSKKAKKALKERKEIEQEMHEAEAEVDKEERAKTHTETLKLLFVLYFKILKLLPPALEGIARFAHLVNIDFFRDLLRVLKELMLLCIVAAFELLSGQLYAIIPELRALSIASWRS--AAFAKRLLTSSLALRAIEFVRTLLVSPDIDDPATTLWELQLL Botci1 KEELARIALML--NEDPENVGAFRAIAEFIKKLALATQLAVYKDVIPGYRIRPLSEDNKVSKEVRKLRAYEQALVGGYQGYVKELGRLALSTVAISCACAL-LEAVPHFNFRSDLLLVGKLSTRCRETIETLFKNDSSLDAVNILTRMMKGRVDESVTKKERKLMKERKAVEKEMVQADATVSHEDRERMQSETLKLVFVTYFRILKLMGAVLEGLARYAHLINQDFFGDLLEALKDLILLCIITAFALLEGQLYRTLHALRSLSSVLLRI--AAFTKQLMTCSLATAMMALLGKVAKIGCSTEVASTIWEGELL Caeel KDTIASHANML--LSNPQNIVRLRDLYNLVQKLAIASTLQVLLDILPGYAIREQTAEEKQKKETRNLVNYEESLLRYHLKYLQLCEKLSMGILSVKALARI-VVSAPHFNYSTNIVLVRL---SVCEAIRTVFKEDITLFTARSISTLVTKRVPPELSKTAKKYKKQLARLEADLLEVEAEESMSKKLKNATEAMKFAFQSYFSILKLLEPVLEGLSKFAHLLSIEFYEDIVSTMENMVLHCINTVFVILSGDAYRVLNHLKTLETMLSRV--AAFVKRLLSIATALCIVSLVRSLFIAPDIDDPSDVRDELSML Canalb1 KEEIAELGSKL--IEDPENIVCLTRLRKMTSQLSILALIPIFKSLAPSYKIRPLTDTEKVSREIAKLRNFEQNLVINYKAYIELLTKYSRGNIALKAATELCLSSLRHFNFREELFIIKRLNKKSLRVLETLLKDDITFDIIKIMTKSIKDKVDESVSKKERKARKERKEIEEEIQKAEQAITVEQREKYQAQVLKMVLTLYLEILKLMGAVLEGLSRFGQMSNLDLLGDFLEVLREIMLLCIATSFSLVLNHLYIILTDLRCLDFIFPRA--TAFIKRLYILTLSLANLKFIGKLMNRLGIERQAATLWENVLL Cangl QEEIADLVDKL--MNEPEYPAALTRLVKMTCIFSMLALVPVFKSVIPGYRIRPLTDLEKVSKEVARLRTFEQGLVHNYKLYLDTLKELAIGRQAVRAANEL-ATTGSHFNYRTELFLVRRIC-KIIKTIEGLFNDDVSAEFMRLLSKVIKTRVEESVSKKQRKARKEMKQIEQEMEKAEQTVSAEERERNQGEILQLMLSLYLNFLKLIGASLEGLTKFGSQVNFDLLGDFLAVMKEIILLCIVSAFSLVSNHLYYVLPYIKALNHIFERA--CAFTKRIYGCILSIALLKFIEKLMTRLFTDAIAAMLWENAVL Capow KQQLAEFASQI--MENPEHVGLFKQIGRFIQKLAMLTAVRVFKDILPAYRIRDTGDEEQVSKEIKKIQAFETALLGQYQQFLL------LAECAITCMGEL-LLQNPYFNFSVNLILVPLMGVRICATIVSLFQNDAVLDVVKVVAKLVKAKLPRTISKKEKKKTKVAAELDRAMRETEAEVSKVDRQRMQTETLKWVFLTYFRVLKLLPGVLEGLAKFAHLINIDFFSDLMSVLKNLLIHCVKAAFQILTGQLYAALP--SCLELMLDRV--AAFVKRLCSIATSLALMTATRGLMKNAELDDPATTLWELPLL Catan2 LERIAIVCQRI--IDSPENISLISRIAELIQAVAIASIGQVFLDVIPGYRIIELTAEQKVSKDVRKLRTFEQTLLATYQKFLTALDGVVPARIAMDIFCKL-LITHPHFNFRLNVIIVKRLTRRILETLRQVFRRDVSSETVRLIARLIKTVVDPEVNKKQRKNSKFTKEVLAELKEAEAVVDLEDRKRQHKITLEHVFLTYFRILKVMPAALEGLGAFAHLVSIEYFDSLFRVFKLLLLSIIATANRVVSGQAYAVIGSLEVVETSVTII--LAMFVRLLSLAAVLAILSLCSTLFAKPWTHDPHAAPYDLALL Cioin KSKISQLASDI--LAEPQSLKMIKDLRLMIKKLVTVSLACLFVDILPGYRIRERTEQEKLSKEVKALTEYEDGLLHQYQQYLQSLEKMIMSEVAVQAMCDL-FKHTSHFNFHNNITLVPIANDDCCDALEAIFLSDSILAAVKAIAKVSKERLRAEFSRREIKQMKKQKKLKNELKEVAAAEDHDEKMALHTETIQQVFLIYFRILKVLPAVLQGLAKFAHMINIDFFSDLFAVLQSLVVHCIFTAFTILSGQLFSLLHEKMCVSIMLNSL--NSFIKRLSTIAVTVKILEEIQKLLNSPYLDDPASCLWEMHLL CocheC53 KEELARIASLI--NEDPEHIGALKTLQALVKKLTLATQASIFKDIIPGYRIRPLSEEKKISKEVKKLRQFEQKLVSGYETYVKHLAKLALATVAVSCACNL-LNAVPHFNFRTELLLVGKLSTRCREAMEKLFENDVSLEGVTMLTKMMKSRFDESVTKRLRKELKEKKAIEKEFKEADAAVSHEERDRMQAETLKMVFVAYFRILKLMGAVLEGLARYAHLINQDFFGDILEALRDIILLCVITAFALLEGQLYRTLHPVRSLSSVLLRV--AAFAKQLMTISMCVAMLGLLNRIAKTPLKPEIAGTVWEGEIL Coere1 QNRLAVIADAI--MQDPDGVKYLKTLHNIVKRLGLLTQLAVFCDILPEYRIRELTEKEKVTKDVRQQRMHEEQLVHSYSNYLKQLFTASTGIVAARALGNL-INVRPLFNFRKDILLVDIYTAR---AVLRLFRDDLSQNAVMLAAKRIKRLVDPSASKKQAKMRKVQQDVDKSLVEAEAEVSREEREKWYGETLKQVFITYFRILKLLPAVLEGLAKYAHLISVEFFVDLFQLLKKIMLLCILSALHILTGQLYALLPPLECLQLMFTRV--AAFCKRIAECALAVRAIEFMHRLLIKRDLDDPATCLFELHWL Conco1 QEEIAKLSLKL--ISNPEKYYLLNDLKKLIKQLSYMANLAIFIDIIPSYRIRQVSEAEKVSKAVKNQREFEQGLLSYYQAYLAALQKEFISSTIIHCFSIL-LEKLGHFNFYEYVICCRRLMSKVFDSCKLVFEEDNSLLITKTLLRLMKNKIPSQTSKKQKKKQKVDKELADELREAEAEYTREEVSKFQSETLKQVFIIYFRILKLIPTVLDGLINFAHLINIDLFPDLFPYLKSLLLKCIHCCFRLLNDELYKILLLMLCLNSAFLRS--QAFLKRLMTISFLLQLLQFLKKLILKAEAEDPSTTVAEFVLL Conpu1 KEQIAGLCSDI--LADPESLGLLRRLHTFIRKLAILSQLAVFKDLVPGYRIRALTDKEKVSQMVARTREWEQGLVTVYQSYLKLLETELLSEVALRCMCTL-AEQVTHFNFRVNLLIISQLSKKCLNTLISIFRDDPSLEIVQLLNRMITERVHPEVSKKAKKALREKKEISRELREAEAEVDREERATTQTETLKLLFVLYFRILKLLPSALRGIAKFAHLINVDFFRDLLQVLRGLILLCIMTAFELLSGQLYAIIPAVRALNVVFWRS--AAFAKRLLTASLSLKTLQFIEQLLGKPDIDDPSATFWELFLL Copci KEQIAGICNDI--LADPESLVLLKRLHSFVRKLAILSQLAVFKDIIPGYRIRALTDKEKVSQMVARTREWEQGLVSVYQNYLRLLDGEILADAAIHCMCIL-LAEVTHFNFRQNLMIVARLSKRCLNTLNSVFRADASLEIVRILNRMVKERIHPNVSKKAKKMLKERKEIEKEMREAEAEVDKEARSVTHTETLKLLFVLYFRILKLLPAALSGIAKFAHLVNIDFFRDLMKVLKELMLLCISTAFELLSGQLYAMLLPLNTLNIVFWRA--AAFAKRLLIASLSLRALSFVRALVARADVDDPESSFYELHLL Croqu1 RVEIADLAREA--IADPESLGLLKRLIALIRFMAILSLLSVFLDIIPGYRIRALGEAEAVSQMVARQREWEDGLVSVYKRFLEICEKEVLAAVGLKCLCKL-LSEKTYFNFSQNIMIVRKLGRKCVSCLRSVLEKDDSLQVVRQVGRIIKSRVHPEVSKKAKKAIKDRMGIEKEIQEAEETVRVEERERNQTETLKLLFALYFRIIKLFPAALDGLAKFAHLVNIDFFRDLMSVLRQHILVCILTAFELLSGQLYAVLIPLRALHLALLRA--QAFTKRLLTISLVLRIFGFLNKLLHRAEVDDVGAVGWE-VWA CryneH991 KEQVAQLGSEI--LGGGEISPVLTRLSSFIRGLVFLSQLAVYKDLIPGYRIRELTALEKVRDEVKRLREGEKMLVKSYKGYLKMLEAEILATISLRCMCEL-LTSVTHFNFSENIMLVGRLGRRVLQTFIRVFREDHSQTLVRLIARMIKERVHPNVTKNQKKREREMKEVQKEMAEAEAEVDKEERAQVQTETLKNLFVLYFSILKLLPAALEGISTYSHFINIDFFRDLLVVLRKIILLAIATAFDLLSGQLFALLRPLRCLNASFNRS--AAFAKRLTECALGKQAIAFARSLVSKPELDDPTTSWWEAGVL Crypa2 KEELAKIGSQL--SEDPEHPGAFKNLAKIVQKLCLVTQLAVYKDVIPGYRIRPSSEDPKLSKEVKKVRTYEHALVTGYQVYLKDLTRYALSKVAITCACTL-VKAVPHFNFRTDLLLVSKLSSRCLRSLEMLFKEDPSMEAVSLLSKMMKAKVHETVTKRERKAMKEEKALAKEMAQADALVSHEERDRMQSETLKLVFATYFRALKLMGAVLEGLAKYAHLINQDFFGDLLEALKDLILLCTVTAFALLAGQLFQSLLPLRCLTAVLLRL--AAFTKQLMTIALCQAMLALINDVSHTPFSESVATTIWEGELL Debha1 KEEIADLASKL--IEDPENVLCLTRLRKMTCQLSMMALIPVFKSLAPTYKIRPLTDTEKVSKDVARLRQFEQSLISNYTLYIDNLSKLAKGQLAAKAACELCISSLRHFNYRNEIIVVRRLNRKCLRVLETLLKDDISFDVIRILCHSIRDKVDESVSKKERKARKERKEIDEEMRKAEQTITIEEREKYQSQVLKMLLALYLEILKLMASVLEGLARFGQMANFDLLGDFLEVLREIMLLCIATSFTLVTNHLHNILCDMRCLDFVFPRA--TTFTKRLYISILSLASLKFIGKLMSRLGIERSAATLWENVLL Dekbr2 KEDIAQMAESL--MENPENVLLFAKLLRMTAKLSLLSVVPVFKSICPSYKVRPLTDAEKVSNDVQKVRFFEQNLVRYYRKYLDVLSLHSLGILSTRAACQL-ASPLRFFNFRSDLMLIRRIMHKCVKTLEALLVEDISLDISRMLSRSIRRRVDESVTKKQRKELKEKKKIEKEIKDAEFKITAEERERFQAEILRTLLTLYLEILRLMAPVLEGISKYGRQVNLDMIGDFLQVLREISLLCVITSFSLLSYLLYGLLPLLKGLNAIFARS--LAFTKRLYTAMLTIAVMKFIGKLISRPYAETIVAVLWENLLL Dicdi KMSLAKASSLI--ISNPENIQAIKELFSIIKKYSILSLCAVFKDIIPGYKIKDLADEIKLSKEIKKIREYEKKLLKFYQNYLVLIENSILLQCILKAVSTL-LITHPHFNFRTNLVITSRFTVYCLEAVKSLFEHDTSLEVVRCLANVAKSAIDPKVTRTEKKKRKEDKSLDKEMKEAEAEFSVKEQKFLQTEILKAIFILYFRIIKALTSVLEGLAKFSHLISVDFLGDLLKVLGDLIFNTNITAFKTIKLHVYSLLTDMDALQLMLERV--ASFIKRLSTIALSLALVSFIKQLFITPEAQDPASTLWELSLL Dmel KYRIGIICSGL--LEKPEKMRNFHALYELVRKLAIISVTEIFKDILPEYRVGQ--VDTTLRKATLDRVTFENALLQQFKKFLQKLEQITLATVAVQCMCDL-LVAHPYFNYVQNIALVYMLNCN--QCFRTVFSNDMTLFIVRRINHLIKTKVHVECSKKERKRRKKLTEVNRELEETRAEENKQAKHQKLTEIIKMVFTIYFRVLKVLSAILEGLAEFAHVINLDFFSDLIDVLNRILLHCVQTIFVILSGQFYR--NMLRTLDEVLQRL--MAFMKRLLTGSLTLATLGTIKQTFQLPELDDPSTALYELALL Enthi -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLVLDTIFRTYFRVLKLVPLVLEGMSIHTHKINYDFMLDIIKLLQQLLIRVCYTIFNTLKLQMYKVLDQIGVLKIMLVRI--ASFVKRILIMMLALDFCAILTWIFKRPSVQQPNSCLWELTLL Falba RECLATLAMRI--TELPEHIGLLAQVKQIVRMLGLATMAALFRDLIPGYRVQDIDPKE-LSKDVRKLHMYESTLLKHYQQFLAQCEAEILSIVAFRCMAEL-LVAKPHFNFRNNLVIVNRLGTAAERSLLEVLKTDVALDVTRAVTKLVRARVPVPASRQQRKLKKLEKEIDRDLRESEATYRREERIRLQTDTLSMVIQIYFRLIKVLPTVLEGLSAYAHLINIDFFQDLLVALRSVALHCVLAAFRLVSNHLFRLLPLLEAIDAMLERI--AAFIKRLFHVASSLLLVASAHSLLRRADADDPSSPLWDLAIM Fomme1 KEQIASICQDI--VADSESIGLLRRLHTFVRRLAILSQLAVFKDIVPGYRIRPLTDKEKVSQIVQRTRDFEQGLVSVYHAYLRVLEAELLAESALQCICQL-LSDLTHFNFRVNLMVVARLSRKCLKTLTFVFRTDASLEIVRLLNRMIKERVHPNVSKKALKKLKETKAIEDEMREANAEVDLEERMSVQTETLKLLFVLYFRILKLLPAALQGISRFAHLVNIDFFKDLLQVLRDHVLHCIVTAFELLSGQLYALILPLRALNLVFWRT--AAFAKRLLIASLAARTVDFVRSLFVKPDVDDPATNLWELQLL Fusgr1 QEELAKIGTQM--NENPEHVGAFKALAKIIQMLALMTQMSVYKDVIPGYRIRPQEENGKLSKEVRTLRQYEQALVSGYQTYIKELARCALASIAITCACTL-VTSVSHFNFRTDLLLVTKLSRRCLEALRELFKEDPTNDAVGLLSKMMKARVDESVTKRYRKDLKEQKALDKDMANADASVSYEERDRMQSETLKLVFATYFRILKLMGAVLEGLAKYAHLINQDFFGDLLEALKDLILLCTVTAFALLEGQLFKTLLTLRSLTGILMRL--AAFSKQLMTAALCQAVLVLLSDVAHTPISDSIAATVWEGELL Galma1 KDQIAGICQEI--LADPESLGLLRRLHTFIRKLSVLSQLAIFKDIIPGYRIRALTDAEKVSQMVARTRDWEQGLVTVYQAYLRLLENELLADTALHCMCTL-LKEVTHFNFRNNLMIVTRLSKKCSQSLSEVFRADSSLEIVRLLNRMIKERVHPNVSKKAKKALKEQKEINKELREAGAEIDKEERKSTQTETLKLLFALYFRILKLLPSALSGISRFAHLVNIDFFKDLMKVLKDLILLCIVTAFELLSGQLYAILLPLRALNLIFWRS--AAFGKRLLTASLALRTLEFVSGLVAKPDVDDPETSFWELHTL Ganpr1 KEYITGVAEKV--IGDPENIPSIKPLLKV---FILTALLAIFADIIPGYRIRARTETEMVSKDVRKLWTFEEALLDGYVMFLEACERVLLAKLANHALRTL-LLQHSHFNYRTNIILVKCITHPTLETLSAMFHADTTIEIVRILGALVKARSPPGVTRRAQKLRKLSKEVDEQLKEAEASVDAEERQNLQKQTLEIVFATYIRLLKVVSEVLSGIGKLARYVSLDFLPDVLVLVRRTAVDAALAAMQLLRGSLFAAITALSALDLMFARP--AAFAKRLLSCSLVQAVISFVQDLLMKPFVDDPSSSLFEVSVL Gloin1 KVQLAEIAQLI--IEDPENIGQLKVLREIVKKLALLTQLVVYKDIIPGYRIRNLSDKEKVSKEVNKIRNFEQSLLANYQSYLQSLENEL----ALQCMCNL-LTSITHFNFRLNLMIVTRMSTRCCDAIIEVFKNDASLDAVKLITKMIKSRVHEEVSRKMKKLDKERKEVERDMKEAEAVVDKEEKEKTHTETLKLIFIAYFRILKLLLSVLEGLAKFAHLINVDFFNDLLELLKEIMLLCIITAFQLLSGQMYTVLLPLKGFDFMFDRS--AAFLKRLSIACMVLICLNKMEKMIQNPELNDPATSLWELDLL Hisca1 KEELARIAELI--NEDPEHTGLFKRLADMVKKLALATQVAIYRDVIPGYRIRPLGEDDNVSKDVRKLRNFEQSLLAGYQNTVKMLASFALKAVSINCACSL-LIAVSHFNFRGELLLVSQLGRRCRETIEKLFANDVSMEAVSLLSKMMKARVHDSVTKKERKLLKERNAVAKDMKEADALVSHEQRDKMQAETLKLVFGTYFRILKLMGAVLEGLAKYAHLINQDFFGDLLEALKELLLLCCITAFALLEGQLYQSLYPLRCLQSTLVRV--AGFTKRLMTASLSLALLSLLTRVAKQPLAETVAGNVWEGELL Klula1 KETIAELVERI--MEEAENTAALTRLRKMTAKFSILALVTVFKSIIPGYRIRPLTELEKVTKEVARLRSFEENLVFNYKAYVDLLARLSLGNIATNAAIEL-TSSSMHFNFRSELLLIRRIS-KAIKTIEGILNEDVSVEVIRLLSKVLKTRVDESVSKKEKKARKERKLIEEEMRAAEQAVSAEERERNQAEILKLTLALYLNILRLVGSVLEGLAKFGHMANFDLLGDFLVVMKELILLCIVTAFSLVSNHLFTVLPYLKALDHVFQRA--AAFTKRIYMALLSIALLKFLDKLTTKIDTDLPAATIWENSLL Lacbi2 KDQIAGICQEI--LADLESLGLLRRLHSFIRKLAVLSQLAIFKDIIPGYRIRALTDKEKVSQMVSQTREWEQGLVGVYQSYLRALEVELLSEIALECMCTL-LTEVTHFNFRINLMVVTRLSRKCLDTLDQIFKADASLEIVRLLNRMVKERIHPRVSKKAKKERKEKKEIDKELREAEAEVDKAERASRQTETLKLLFALYFRILKLLPAALSGISKFAHLVNINFFKDLLKVLKDLILLCIVAAFELLSGQLYALILSLRALNIIFWRS--AAFAKRLLTAAVALRAIEFVAGLVAKPEIDDPGSSFWELHAL Lenti61 KEQIAGLCQEI--LGDPESLGLLRRLHTFIRKLTMLSQLAVFKDIIPGYRIRALTDKEKVSQMVQRTRDWEQGLVGVYQTYLRSLEAELLAETALHCMCAL-LVEATHFNFRVNLMIVAALSRKCLDTLVKVFRADPSLEIVRLLNRMIKERVHPEVSKKAKKALKERKEIEKEMHEAAAEVDKEERATRHTETLKLLFVLYFSILKLLSAALRGIAKFAHLVNIDFFKDLLQVLKTLMLLCIVTAFELLSGQLYTILPQLRALHLAFWRS--AAFAKRLLSAALAARAIELVSVLVERPDVDDPGTSFWELRLL Malgl1 REQIARLSSSI--MADPEGQASLRRLLVFIRQLAMLSLLAVFVDILPGYRIRALSETERVSQDVARRRDWEQGLVRLYRDYLECCEGDVLAPVARKCFCTL-LVRAPHFNYRKNLLVISLLSRKCFEALAQLLRQDLGLELVMLLYRMIRERVHANVSKKQVKRDRELRQIEHEMREADATLDLEERERRQSETLKLMFALFFRILKLLASALEGLVHFAHHVSADFFRDVVGVLRTHVLLCIVAALELQAGQLYQVMWPLHALELALDRT--AAMLRRLLMSALTLHALQ-IAHAILAPYSEQPQP-CWELIML Mellp23 RAEIADLAREA--ISDPESLSLIKRLIALIRFMALLSLLSVFLDIIPGYRIRALGDAEAVSQMVARQREWEDGLVSNYKKFLEICENEVLGSVGLKCLCKL-LAEKTHFNFSQNIMVVRKLGRKCLDAIKAVFRKDDSLQLVRLIGRIIKARVHPEVSKKAKKAIRDRRGIEKEIQEAEETVKVEEKERNQTETLKLIFALYFRILKLFPTALEGLAKFAHLVNIDFFRDLMRVLRQHILVCIRTAFELLSGQLYSILIPLKALNLAFLRA--QAFTKRLLTITLIIKIIKFIIKLMHRGELNDVCAIGWE-VLA Mnele KQEIARLSCAI--TEDPYNISAMKKLRHYVRKLAMISLTAVYNDILPSYSVKPSKELESLSKEVKAQHSYETDLLRNYRVFLDLLFDNLLGLLSLKCMAEL-LSRNYNFNLRSNIVLIPYGASKVTATIVEIFEKDCSVEIVRMIAALVKKKVNGKLSKKQRKHRKEQAKVRKELLEAEAVENKKKKSRLQSESLDHIFVTYFRILKLLPIALAGLSKFAHLINVDFFTDLFECLKRIILNCVSTIFTILSGQLYQNILLFQAL---------TNTVKRKVPLSC------------------------------ Monbr KEEIARLCSSI--IEDPERHKLLADLLELVKNLAILSTAAVFKDIIPGYRVRSLSEKEVVSKDVAKLRAFEQGLLTHYQAFLKLLHNTILGLCAVGCLSDL-LAEAFHFNFRNNIILVPLMTGNSLKAARTVIISDATLDLVRSICTHVKAICDPEATRRKRKELKAEKQLSKELLEIEATTNTKRLSHNQTQILAQMFAVFFRVLKILSVALEGLGRFAHLIDTNFYDDIFRALEDLILSSIKAAFRILSGELFRCLAELDCINSTLERV--AAFAKRLLVVSLEVAALVMVKLLLQKPEMESPTTALWE---- Morel2 KEEMATIAQTI--IADPENVGQLKKLRAMIKKLALLTQLAVYKDILPGYRIRPLSEKETVSKEVAKLRDYEQSLLLNYQHYLQSLEKVLMATVAIHCMCNL-LTSVTHFNFRLNLMLIARMSRRCSKALKEVFTEDVSLDAVKLITKMIKSKVHPNVSKKNRKLLKAKKEVEVEMKEAEAVVDKEEKMRMQTETLKLVFITYFRILKLLPAVLEGLAKFAHLINVDFFTDLLEVLKKIMLLCIVTAFQLLQGQFYTSLLTVKGFELLFIRA--ASFLKRIAVASLMKDFLAIMKKLVQKPALNDPAASLWEFELM Mucci2 KEELALIAGNL--QGDPEYVSQLKTLRTIVKKLALLTQLAVYKDIIPGYRIRPLTALEQVSREVKKMREYEKALLSNYEMYLKDLNVLLLAFVATRCLCEL-LIAKTHFNFRLEIMVVTRMSTICSEALVTVFENDSSLDAVKMIIRMVKSKISENATKKARKTLKETREIEKEFQEAEAVVSKEEKEKNHTETLKLIFTFYFRILKLLPAVLEGLSRFAHLISVDFFDDLLNALKDVMLLCIITAFQLLSGQIYNILFKAKGLELMFNRL--AAFTKRFTLVALVLQCLALVDRLVQKPLLEDPGTSLYELFLY Mydma KIEIAHISQSV--IENPESFGLDLHLDRR------------------SYRIRELSEEEKISWDVKKIREFEECLITSYQSYLQSLEDTLLAALCTKCFCEL-LESASHFNFRTNIIIVPKMELSCFNTIKNIFCNDISLEVVKFINKLVKSKVKSQVSRKEKKNL--------------------------------------------------------------------------LHCISTAFKILSGQLYNLLPFIECLDMMLPQV--LGFFKRLSTMLLMLDFLALVRNILQLPDISDPSSCLWELTLA Neucr2 QEEMAKIATQL--NEDPEHPGAFKALAKIIKKLAIVVQMTVYKDVIPGYRIRPASEDVKLSKDVKRLRVYEQAMVTGYYQYIKTLAALAISSIALTCACTL-LNAVPHFNFRGELLLIKKLSYRCRTALETLFHEDPAMEAISVLTKMMKARVDESITKRERKLLKEQKEAEKVMAHADAAVSYEERERMQSETLKMVFASYFRILKLMGACLEGLARYSHLINQDFFGDLLEALKDLILLCTVTAFALLEGQLFQSLLSLKCLSGILLRL--AAFTKQLMSGSLAQALLGLLADVLHTPLAATVASTVWEGELL Orpsp11 ----------------------------------------------------------------------------------------------------------------------------CCKSIATLFTKDYSLEAMKLISRLIKNKVREQVTRKARKVLKENKEVEKEMKEYEATIDLEKRQKMQTETLNILFALYFRMLKLLPTVLEGLGRFAHLINIDFFDDLIAVLKNIMFHCIIAAFQLLFKQMYAQMIRLIGFEFLFERI--AAFIKRLATITIVLASLYMIKSLFI----------------- Pench1 KEELAKMATLI--NEDPEHISLFKTMAEMVKKLALASQAALYKDVIPGYRIRPLSEEDRVSKEVRKLRDFEQSLVSGYRAYVQKLATLVLRSFAISMACTM-LLAVPHFNFRSELLLVNRLARRCRETMEEVFAKDVSLEAVRLLAKMLKARIHPSVTKRERKIQKERKEVEKDMRQADAVVSHEQRDKNQAETLKLVFGLYFRILKLMGPVLEGLAKYAHLINQDFFGDLLEALKDLILLCTVTAFALLEGQLYRSLYSLRCLQPTLSRL--ASFSKRLMTTSLALATLALMNQVSKYAFAADIAGSVWEGELL Phybl2 KEELAQMASEI--QEDPESAGQLRFLREAVKKLVILTQLAVYKDIIPGYRIRPLSDKEQVSKEVKKLRDYERQLLHNYEEYLKDLESLITAMIATRCLCEL-LTTKTHFNFRLNIMIVTQM---CNQAIITVFINDTSLDAVKMMTRMIKSKVHEKVTKKARKARKETREIEKEFQEAEAVVSKEEKDKNHTETLKLIFAFYFRILKLLPAVLEGLARFAHLINVDFFDDLLNAIKDVMLLCIITAFQLLSGQMYVFLLKAKSLELMFNRM--AAFAKRLAMSALVLQCLGIIHRLLQKPLLGDPGTSLYELFLY Picst3 KEEVADLASKL--IEDPENISCLTRLRKMTSQLAIMALIPVFKSLAPSYMIRPLTDAEKVSREVARLRAYEQSLVSNYTYYIDNLGKMAKGALATKAACELCLSSLRHFNYRNEVFVIRRLNKRSLRVLETLLKEDITHEVIKLMCKSIRDKVDESVSKKERKARKERKEIDEEMRRAEQAITVEQREKYQAEVLKMLLMLYLEILKLMASVLEGLARFGQMANFDLLGDFLEVLREIMLLCIATSFSLMLNHLYLILADLRCLDFIFARA--ASFTKRLYLTALSLATLKFIGKLVSRLGIERDAATLWENVLL Plicr1 KDQIAGICQEI--VAEPESLGLLRRLHTFIRKLALLSQLAVFKDIIPGYRIRALTDKEKVSQMVAQTREFEQGLLVVYQTYLRSLEAELLAEVALQCMCTL-AAEVTHFNFRVNLMIVAHLSKKCLNTIISVFRDDPSLEIVRLLNRMVKERVHPEVSKKAQKTMKEKKEIEKEFREAEAEVDKEERAVAQTEALKLLFVLYFRIIKLLPAALRGISKYAHMVNIDFFKDLMKVLKDLILLCIVTAFELLSGQLYAIILPLRALNIVFWRS--AAFAKRLLTASLTLRTIDFVAGLVAKADIDDPGTSFWELHLL Polpo KIRIAQISMKI--TENPENIGLLNDIFAIVKRLGVLSLCAIFKDIIPGYKISQLHKEDTLSKEIKQTRIYEAKLLKFYQNYLVLVEGTVILAVVVKAASSL-LVSKPHFNFRTNLVLTARFTVYCIKAVHDLFRNDTALEVVRCMSNVAKATLDPTVTQKEKKERRDEKKLAKEMNEAEAEYTMKEQRYLQTEILKSIFITYFRIIKALTAVLEGLVKFAHLISVDFLPDLLAALASLILNTSITAFKTVKQHIYSLLPQLAALQYMLDRV--ASFIKRILTLSTALALITFCKQLFVSGETPDPSTSLWELTLF Pucgr2 KLEIAGLSQEA--ISDPESLGSLKRILAMIRIMAILSLLAIFLDIIPGYRIRAITDAEKISQMVARQREWEEGLVSIYRRYLEICEKEVLSACCLKSLCTL-LQSKTHFNFSHNIMIVRKLGQRCTETITAVFKKDDSLQLVRLIVRTIKSRVHPELSKKARKIMKARAGIEEEIAEAEETVKVEEKERNQTETLKMMFGCYFRIVKLLPVALEGFSRFAHLVNIDFFRDLLEVLRKHILLCIVTAFELLSGQFYGLLMDIKVLDLIFNRA--ILFSKRLLTISLVLKLLKFLTKLTTRDHLEQEDQLGWE-LFL Punst1 KEQIAALCQEI--LADPESLGLLRRLHTFIRKLAILSQTAVFRDVIPGYRIRSLTDKEKVSQMVARTRDWEQGLVGVYQHYLKSLEAEILADLALQCMCKL-LVEVTHFNFRANLLVVARLSRRCLDTLIKVFRVDVSLEAIRLINRMVKERVHPNVSKKARKALKEKKEIEKELHEASAEVDKEERANNQTETLKLLFVLYFRILKLLPAALQGIARFAHLVNVDFFKDLLNVLKELVLRCIIAAFELLSGQLYGILPTLRALDLVFWRA--AAFSKRLLTAALAARAIAFVQTLVARPYVDDPGTAFYELLLL Rhior3 KEELAQIAARL--QEDPENVGQLKKLRTIIKKLALLTQLAVYKDIIPGYRIRPLTQEEKVSKEVKKLREYEKSLLQNYEQYLKDLNVLLLSLVATKCLCDL-LVAKTYFNYRLEIMVVARMSTVCKNAIIEVFENDYSLDAVKMITRMVKSKVSENITKKAKKALKETKEIEKEFREAEAVVSKEEKEKNHSETLKLIFAFYFRILKLLPAVLEGLSKFAHLISIDFFDDLLNALRDVMLLCIITAFELLSGQIYNILFKARGLELMFDRL--AAFVKRFALVALVLQCLHLMQKLVQKPLLSDPGTSLYELFLY Rhoto1 KEEIADLGREAAGTGEGEGLNLLKRLLSLIRIMAMVSLLAVFIDVIPGYRIRELSEAEQVSQIVARQREWEHGLVATYKKFLEICEGEVVAPAALHCMCTL-VREKPDFNFAVNIMIVKRLGRKCLDAVIYLFQNDNSLHLVRLISRLVRARVRPEVSKKARQARKEQEAVEKEMREAEGVINQEERERNQTETLKLLFALYFRIVKLLPAALEGLARFAHLVNIDFFRDLLEVLKG--LLCIVTAFELLQGQLYSLILPLRALSAIFVRT--LAFSKRLLSASLQLRTLSFLRSLLIRGHVDEPSTCWYEASVF Rozal11 EEKMAQAALDI--LSDPQNLGQLKKLKTSHKIYLILTLCSLYKDLIPEYRIRPLTEKEKVSNDVKKLRDFEQTFLSHYQGFLKEVEFILLLLACIECLCQL-MIKAPYFNFFKNIVIVGRFTLNCCNSMKALFQGDVSLQGIQVLYALIKKKVPCRVKNQKKKLKKDEKMLEKEMKEAEAIVAFDEKQAAYKETLKLIFYIY-----LLVSVLKGISKFVHLVDYKLVVDIIKTVKERTLSCVMTAVAAAENELYNLI---TCFKSLFNRV--ASFAHKLSKVAIRLKLFNIIVHLFIKEKAKDPSTKLLEYEKW Sacce1 KEDIADLVTKV--MEEPENTAALGRLCKMTCKFSMLALVPVFKSIIPGYRIRPLTETEKVSKEVSKLRNFEQALVYNYKNYVGRLQSLSLGILATQAAKEL-ISTASHFNFRTDIFLLRRIC-KIIQTFETLLNEDISFEILRIFNKILKTRIEESVSKKQRKARKEMQQIEEEMRNAEQAVSAEERERNQSEILKIVFTIYLNILKLIGSVLEGLTKFGNMANFDLLGDFLEVMKELILLCIVSAFSLISNTLYALLPYIKALDHVFERA--TAFTKRLYMCISSIAILKFIDKLMNRMEADNPAATLWDNALL Salro KEEIASACSAV--LEAPEHITKLGSIIDLVRKLAIASLTAVFRDIIPGYHIRQLTEKERMTKEVKQVREYEGSLLKMYQAFLQHLHTCILALLAAQSLCQL-LETAPHFNFRNNIIITPLMTGKTTSCAIDVFKADVSLSLAKAIAQEIKTSVDPQMTRRERKELKAEKELSKELMATEKEANTKKLEHNQTQILKVVFAVYFRVLKTLPTVLEGIAHFAHLIDVAVFFDLLEVLKEVIMTAISAAMTLVAEELFVHIPATACTNLLLDRV--AGLVKQLLDVCLVVATQALVRDVVRKPRAVLPATALWEG-AL Schco3 KDQIASICQDI--VADPESLGLLKRLHSFIRKLAILSQLAVFKDIIPGYRIRALTDKEKVSQQVARQREYEQGLVGVYQAYLRALEAEILAEVALQSMCAL-LKEVTHFNFRTNLMIVARLSKKCLATINAVFRADPSLEFVRLINRMVKEKVHPNTSKKARKNEKERKEIEKEMKEAEEVVDREERQATHTETLKLIFVLYFRILKLLPAALRGIARFAHLVNIEFFRDLMAVLREIVLLCINTAFELLSGQLYALTIPLTMLS---PRALMPAFAKRLCTACLAVQALDVVRTFTVRAALDDPSSALWEVTML Schpo1 KEALGIQAQQL--LEEPVNLHLIRNIFEKIKKLSLLTLLAVFRDIIPGYKIRPLSEEEKLSKEVAQRWEYEQTLLKHYAKFLQTLETILLYQVAVRCCTKL-IEQASHFNLSEKLFAVRQISHKIINSLKNIFEEDTSLKCVTILSRMFKQRVLPDVTKKARKNYKETKKITQEMKEADAVITAQDKEKYQSEILKIIFITYFKTLQLIGNALEGVARLSHLLNIEFLGDLLQVLRELVLLTVSTAFEIASAQLYKIIFPFKCFQVFFSRL--SSFSKRLAIASMASADLALLKKLLSRPFIEDPTAVLYEPFLL Sorma QEEMAKIATQL--NEDPEHPGAFKALAKFIKKLAIVVQMTVYKDVIPGYRIRPASEDVKLSKDVKRLRVYEQAMVTGYYQYIKTLAALAITSIALTCACTL-LNAVPHFNFRGELLIIKKLSYRCRTALETLLHEDPAMEAISVLTKMMKARVDESITKRERKLLKEQKEAEKVMAHADAAVSHEERERMQSETLKMVFASYFRILKLMGACLEGLARYSHLINQDFFGDLLEALKDLILLCTVTAFALLEGQLFQSLLSLKCLSGILLRL--AAFTKQLMSGSLAQALLGLLADVLHTPLAATVASTVWEGELL Sphar RQQIAKLSQLL--LEDCENMTAFAQLLEIARKLALVSLMAVYKDVLPGYRIRLPTEAEKVSKEVAVLRAFEASLLGSYQKYLQFMQKMLLVEVCVKCMGEM-LLAKPSFNFGNNII-ILPFAQEVCSYVRQLYSGDSVLEVTRGIAQMIKTHARRELSKKQRKKNKLDKELERDLEKASALENQKELKLRYNEILKMVFLTYFRILKLLSATLKGLARFSHLINVDFFTDLLKAFKRTLINCVATSFQICSGQLYVLLLSLECFDYV-ERV--ASFVKRLVTVALAIALLAYAYQLLLKPFATDPSCPLWELIPL Spipu1 QEKLAEIASTI--IEDPEHIAHLKNLRQIIKKLALLTQLAVYKDIIPGYRIRQLTEEEKVSKDVKRLRQYEETLLANYQAYLQILENTVLLVIAIQCMADL-LTSVTHFNFRLNLLVVARMTLKCCNALCTLFDNDVSLEAVKLIAKAIKAKVQEEVSRKKRKIEKHNKEIEKEFKEAEAVYDREEVKKRHTETLKFVFLTYFRILKLLPAVLEGLARFAHLINVEFFADLLNVLKRISFHCVIAAFQLLSGQMYTQLMRLQGFELLFERV--AAFVKRLAIVALVLACLAIIRSLIIRPMLDDPATNLWEMTLF Sporo1 -----------------------------IRVMALVSLLAVFIDVVPGYRIRALTEAEKVSQIVARQREWEDGLVSTYKKFLEVCEHEVLAPAALHSLCTL-VKEKPDFNFGVNVMVVKRVGRKCLDTIVHLFQTDNSLHLVRLISRLVRARVRPEV---------------KEMREAEGEINSEERERNMTETLKLLFALYFRVVKLLPAALEGLARFAHLVNIDFFRDLLEVLK---LLCIVTAFELLQGQLYAIILPLRALSAVFVRT--MAFSKRLLTSSLQLRTLGFLRSLLIKGHVDEPSTCWFEGIML Stehi1 KEQIAGICQEI--IGDPESLGLLRRLHTFIRKLAILSQLSVFKDVLPGYRIRALTDKEKVSQMVARTREWEQGLVGVYQSYLRSLDAELLADVALRCMCTL-LVDVTHFNFRENLAIVARLSKKCLNAIVSVFRNDASLELVRLLNRMVKERIHPNVSKKAKKVLKERKEIEKEMKEAEAEVDKEERSSHQTETLKLLFVLYFRIMKLLPAALQGISRFAHLVSIDFFKDLMKVLKELILQCIVTAFELLSGQLYSIILSSRSLQLAFWRS--AAFAKRLLTASLTLRTLEFVRTLLVRPDLEDPGTSFWELGLL Tapde11 QEHLAKVALEI--IEDPENIGQISQIRDVEQRFAIMTLSTVFRDIIPGYRIRPLTDLEKVSKEVRRLRNFEQVLIEQYKLFVMSLLQLSIKTTAITAACSL-LESVPHFNFRTELFLANQVARKCRETIEALFRNDASFEGMRILCKKIKDRIDQSTTKKLKKFIKDQKDVEKDMEEAQATINSEVRERLQGDTLKLVFTTYFRILKIVGAALEGLARFANLINVDFFGDLLEVLKELMLLCIVTAFTLLSGQLYQILLPLRTLDAVFNKL--APFVKRLLTIALSIAILELNKRLLARGYTDNYTTSIWETSIL Thetr KRDIAEGVQLL--LEAPEHIHGLDEMLQLVQRYAVAGLTTVYKDILPGYRIRTLTDHEKVSKAVSAQRASEQGLVHSYQAFVQLLD---DAKLYVTSVCTL-VIHKPHFNFSTDLIILRGVNSKCYDAMVEVFDVDITLAAIGLIASLMQAKASPKLSGKQRKELKARRKREMALAKESAEVSKYERQLLQTDILSRIMLAYFRVLKLLPAVLAGLEKHAHLVNVEFTGDLFAALAAIVCYAIHTALGLVDGLLYTTLAEVNLERAFAPRV--AAILKRMASLATTISIIWMIRKVMLKDEVDDPAATLFELMAL Treme1 KEQIAQLGAQI--MAGGENGPLLTRLSTYIRGLALLSQLAVFKDLIPGYRIRQLTQQEKVRDEVKRLREGEKVLVKCYRGYLKMLEAEVLASLSLKCLCEL-LSSVPHFNFSENIMLVSRLGRKILQTFITVFRNDHSQTLVRLVARMIKERVHPNVTKNEKKREKEMKETKKQMAEAEAEVDKEERAHVQTETLKNIFVLYFSILKLLSAALEGISQFAHFINVDFFRDLLTVLRLIVLLAIATAFDLLSGQLFSLLRSLRCLESIFWRA--AAFAKRLTECSLAKKAIGFVRKLMARPELDDPSTSLWEVHLL Trire2 QEELAKLALAL--NENPEHIGSLKSLAAFIRMLALMTQMSVYKDIIPGYRIRPQTEDGKVSKEVRTMRQFEQALVSGYQNYVKELARCAVAGIAVTCACTL-IAAVPHFNFRSDLLLVNKLSRKCLQALETLFREDPTLEAVSLLSKMMKARVDESVTKRQRKAIKEQKSLEKDMAAADALVDHEERDRMQSETLKLVFATYFRILKLMGAVLEGLAKYAHLINQDFFGDLLEALKDLILLCTVTAFALLEGQLFTSLLTLRSLIAILLRL--AAFTKQLMTAALCQAALGLLNDIAATPLSDTVAATVWEGELL Umbra1 KEELAQIASTI--MEDPENIGLLRTLKAIVAQLALLTQLAVYKDIVPGYRIRQLTEKEEVSRDVKKVRAFEQTLLASYQAYLTDLEQ-INAMVATQCMCQL-LTNLTHFNFRLNLMVIAKMSTVCCNAIIEVFRHDASLDAVKLISRMVKSKINESVSKKQRKVMKENKEVEKEMKEAEEVVTKEEKDKTHTETLKLVFACYFRVLKLLPAVLEGLAKFAHLISIDFFRDLLEAMKAVMLLCSITAFQLLSGQIYRLLLPMKGLELMFPRA--AAFIKRFSTSALIQHYLTFVKKLLTRPTLDDPATSLYELYLY Ustma22 RNQIASLASQI--VADPENLGLLRRLAVFVRQLAMLSMLAVFVDILPAYRIRSLTDKEKVGQDVARRREFESGLVQVYKQFLQLCEVEVLEKAAIKVFTTL-ATRAVHFNFRTNILVVARMSRRCYQAISCVVLSDVALEVVRLIHRMTKERVNSRVSKKQLKKQKQLKQIEQEMKEAEATVDLQERERNQTETLKLVFVLYFSVLKVLESTLKGLSMYAHRVNVDFFRDLLDVLKKHIVLALKTTFDLFLGQLFYLPFVN---------L--AAFAKRLAIISLAGKVVRLIAQLVTKALGNNLQTILWELCHL Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 KEEIADLVEKI--LEEPENVPALSRLCRMTCKFSMLALVPVFKSIIPGYRIRPLTELERVSKEVGRLRHFEQSLVGIYKNYVDILKELSIGALATQAANEL-ISNASHFNFRTEMFIIRRIC-KSIKTLESLLNDDISLEIVRILCKTAKTRVEESVSKKQRKSRKEMKQIEEEMRKAEQSVTVEERERNQAEILKQVFSLYLNILKLVGAVLEGLVKFGSMANFELLGDFLEVMKELILLCIVSSFSIVSNHLYALLPSIKALDYIFQRA--AAFTKRIYMSMDSIALLKFLDKLMNKMEADTPSATLWENSLL [Cluster1861.fasta_al_trimmed; alignment length = 92] Allma1 VRLLTHNMLQC-HVKNCIEQHEEINKEFLVNML--PRIDWNALRTTVDQLGDEAFLAALHRALMEIQSGSMVCPE--CEHVYPIRDGIPNML Ashgo11 MKFLTTNFLKC-SVPACLQQDSEFNPDFLLRIL--DRVQWDAIVMVAADLGDAAILRDIHVLLLQIIEGEMQCRN--CGHTYYIKNSIPNLL Aspfu1 MKLVTANFLTC-AVKGCLELEEDFQPEFIRNII--PRVDWDGLRVTANELGDEQTLKDLHRLLLEVIEGKLVCGN--CGHEYLIKEGIANFL Aurde31 VRLLTHNLLAC-HAKNCVALREDYSEEFLRGFI--PRLEWTALVQAARQLGSEDQLKALHRVLLEIEEGSMVCPN--CQHVYPISNGIPNML Batde5 MRIITHNMLQC-HVKGCVETIEDFSSGFIRRLI--PKIHWPAFVHTALSIGNEELLHLIHKVALEVKQGKMVCLG--CKHEYVITNGIPNML Botbo1 VRLITHNLLAC-HAKGCLENREEYNPEFLKGFM--PKIEWNALVSTARELGTDEFLHALHHVLMEVEEGSMVCPN--CQHVYRISNGIPNML Botci1 MKLLTLNFLTC-A------------------------------------LSDEKMMKELHTLLLEIDEGSLVCAN--CGHEYRVKEGIGNFL Caeel MKLFVHNFMSSRFLKN-KQFVEEFDRDNTIVML--DRIQYEALIVAAAAVNTDEQLRVFHHLLMNVIDGELICPE--TKTVFPIRDGIPNML Canalb1 MKFLTTNFVKC-AVKSCLVQEEDYNPEFIVHML--DRLDWNAIIQVAKDLGNQAILKDLHTLLVEIIEGKMICKN--CQHIYYIKNSIPNFL Cangl MKFLTTNFLKC-SVKGCLVQDEEFNPEFLINIL--DRVDWPAVVRVAHDLGQVAVLRDLHTLLLQIVEGQMSCRN--CGHIYYIKNSIPNLL Capow MRLLTHNLLQC-HVKGCVVHKEDFNPEFITHML--QKIEWNALRTTASALGQEELLKQIHLVLMEIMDGKLVCPG--CSHEYLVTHGVGNML Catan2 VRLLTHNMLQC-HVKNCIEISEEINTDFLVNML--PRIHWPALRSTATELGNQDFLQLLHRILMEIKSGSMVCPN--CEHVYPIRDGIPNML Cioin MRLITHNMLTS-HV----KEQEDFNPDFISRMI--TRIEWPALTKAMEMIGNNDFLKQAHHALMEVITGSLTCPE--SGREFPIANGIPNML CocheC53 MKLLTLNFLTC-AIKACLEIVEDVNLAFLKNIL--PRILWNELRVICSELGPSQTAKDLHRILLEIKEGKLVCGA--CQHEYAVKEGVANFL Coere1 MRLITHNMLKC-HVKNCLEQIEERNDEFLVRML--PRLDWSALLKTTKELGDDEFLQALHTAILEVKEGSMICNG--CGHEYKITKGIPNML Conco1 MRLITHNMIQC-SVKNCLAYEEELNLDFLVNML--PKLEYTALRNTALELGNELFLNELHKLLMDVQSGLMKCMG--CNHIYPIKDGIPNML Conpu1 VRLITHNLLAC-HAKGCVEIQEDINPEFVRNML--PRLEWKALVDAARQVGDDELVQKLHRVLMEITEGAMICPN--CEHVYPISNGIPNML Copci VRLITHNLLAC-HVKNCLEIREEFNPEFLKGFL--PKIEWKALVDSARQLGDDEFLKNLHHVLLEVEEGAMVCPN--CKHEYPISSGIPNML Croqu1 VRLITHNLLAC-NARTCIEERSELNKEFLLGFL--PKLDFEALLQASRALGDDQTWAALHHALLEVQEGQMVCPS--CSHIFVIKDGIPNM- CryneH991 VRLITHNMLAC-HVKNCLVERPPINPDFIKRFL--PKLDWKALVDTARSLGTDEEIQALHHVLFEVEEGIMTCRG--CGHAYPVSNGIPNML Crypa2 MKVLSINFLTC-AVKACLAQDEEVNPQFLVNLL--PRLDWAALKTTTTELGNETMLKELHSLLVEMMEGKLVCGN--CGHEYHVKEGIANFL Debha1 MKFLTTNFVKC-AIKSCLAQEEDYNPEFISHIL--ERLDWDAIIKVAADLGNQVILKDLHNLLVEILEGKMTCRN--CGHIYYIKNSIPNFL Dekbr2 ----MTSSVWC-AVKSCLQLEEEFKPAFIIAML--QRINWQALVKVAADLGNEALLKELHTLSIEITEGKMVCEN--CGHIYYIKDSIPDFL Dicdi MKILTHNMMAC-----T-IVLEEFNYEFTKNIY--PKLDWLGIAEISIKFNDEEFLKTLHNLLCNVITGSLTCPN--CQRVYPIDKGIPNML Dmel MKLSTYNFLTSVAI----EVVEEFNPTFVERIL--PKLDWSAVYGAA----NELLLQKLHHLLFEVLEGQLECPE--TGRVFPISDGIPNML Enthi MKLFTHNLLIC-TKRQC-----PLDADFLISLVESERLNWNGLVTSAANIGNQQFLQALWDVVMDVIEGELICPV--CGRHYPIHNGIPNML Falba MRLLAHNLMCS-HV---DEVAEEYNDDVMANIW--PKVVYSVLHQAASALGTEQERKTIYRILFYVVEGSLTCPE--SGRVFPIVKSIPNML Fomme1 VRLITHNLLAC-HVKGCVELREEFNADFLRNFA--PRIEWKPLVDAAKQLGDDEFLKALHHVLLEVEEGAMVCRN--CGHVYKIMNGIPNML Fusgr1 MKVLSLNFLTC-AAKACLVQDDELNPDMIINVL--PRLDWEALRTTASELGDDKTLRDLHHLLLEMSEGKLVCGS--CGHEYAVKEGIANFL Galma1 VRLITHNLLAC-HAKDCLEIREDFNPNFLRGFM--PKIEWKALVDTAIQLGDDEFLKNLHHVLLEVEEGSMTCPN--CKHVYPISNGIPNML Ganpr1 MRLITHNMLQC-PVKGCIENADDFNPQFLKRML--DRIAWGALVQTSFSLGDDEFLQTLHHVLLEVKEGRMVCNG--CGHVYPIREGIPNML Gloin1 MRLVTHNMLQC-HVKGCIEIQEDFNPKFLRNML--SKLEWNALVKTALEINDEEFLKMLHRVLLE--------------YLF---------- Hisca1 MKILTANFLTC-AVKACLKQEEEFQADFLRNIL--PRIDWDALVVTAGELGDER-LHELHRFLLEVVEGKLVCGN--CGHEYQIKEGIPNFL Klula1 MKFLTTNFLKC-SVKGCLEQDEEFNPEFLLRII--DRVDWQAVVSVASDLGDMVILRDLHTLLIQIVEGQMQCKN--CEHIYYIKNSIPNLL Lacbi2 VRLITHNLLAC-HVKGCLELREEYNPEFIRGFL--PKIEWKALVDTARQLGDDEFLKNLHHVLLEVEEGSMICPN--CKHDYPISNGIPNML Lenti61 VRLITHNLLAC-HAKGCIELRDEFNADFLRGFL--PRIEWPALVGAARQLGDDEFLQKLHHVLLEVEEGAMVCPN--CKHVYPISNGIPNML Malgl1 -------------------------------------------------------------------------------------------- Mellp23 VRLITHNLLSC-NSRTCLETIPNFNKEFLMGFL--PKLDFNALLEASRSLGPDEIWLALHHALLEVQEGQMVCPS--CSHIFVIKDGIPNML Mnele MSLICSTCLKRIGLTQCVDVKEEFNPDFINRML--SRLEWPALVQIANQLGDEDVLKKIHHVLLEVVEGELECPE--TGRKFPISKGIPDMR Monbr MKLLTHNMLKS-HV----ELKETFNADFVVRML--DRIVWPVLRQTAIEIGNEEFLRAMHHVLLEVLEGELECPE--TGRKFPIKKGIPNML Morel2 MRLITHNMLQC-HVKGCLEQEEEMNEDFLRNML--TKIEYDALVATCLKLDNDEFLQILHRVILEIKSGKMVCPN--CQHNYIIRDGIPNML Mucci2 -------MLQC-HVKNCVELIEDFNPEFLANML--NKIEWDALYNTAVQLGDEDFLKLVHNVLLEVQQGQMVCPN--CAHVYKIRDGIPNML Mydma MKLLTHNLLTC-NI----VVKEDFNPDFIARMI--HKIEWKALVSAAQNLGNEEFLKDTHHVLIEIMEGNLICPE--TGRKFPISKGIPNML Neucr2 MKVMTLNFLTC-AVKNCLAKDDEINPQLLINVL--PRIDWAALRTTSTELGDEALLKELHELLMEMMEGKLVCGH--CGHEYAVKNGVANFL Orpsp11 MRLITHNMLQC-HVKGCIEELEEFNADFIKSML--NRLDWKALAQTTFS------------------------------------------- Pench1 MKVITANFVTC-AVKECLEQQEDFQPEFIRNIL--PRIDWEALRTISNELGNEQTLRDLHRLLLEVTEGKLTCGN--CGHSYMIKEGIANFL Phybl2 MRLITHNLLQC-HVKNCVELIEDYNPEFLVNML--PKIDWPVLVNTAKQLGNEAFLQGLHSVLLEIQQGRMICPG--CGHVFNIKEGIPNML Picst3 MKFLTTNFVKC-AVKGCLVQEEEYNPEFLVHML--ERLDWNAVIQVARDLGDQAVLKDLHTLLVEIVEGRMTCNN--CQHVYHIKNSIPNFL Plicr1 VRLITHNLLAC-HAKGCVVLREEFNEEFLRGFL--PRVEWGALVGAARQVGDEDFLKKVHHVLLEIEEGAMICPK--CAHSYPISNGIPNMV Polpo MKILTHNMMAC-----T-SKLEEFNVEFTKNIF--PKLDWKGITMVAAQFNDEEFLKNLYNLLCNVMTGQLTCPN--CQRVYPIDQGIPNML Pucgr2 VRLITHNLLAC-NAKNCVEIKEELNKEFIKGFL--NKLDFDALLYASRALGPDETYAALHHALLEVQEGNMVCPS--CGHIFVIKDGIPNML Punst1 VRLITHNLLAC-HVKGCVVVREDYNPDFLRGFL--PRVEWQALVGAARQLNDDDFLKKVHHVLLEVEEGAMVCPN--CKHVYPISNGIPNML Rhior3 MRLITHNMLQC-HVKNCVELIEDFNPEFLANML--NKIDWDALRNTAIQLGNEEFLKVLHSVILEIQQGQMVCPN--CSHVYKIKDGIPNML Rhoto1 VRLITQNLLSC-PSRACLEMVEDFNEEFLRGVL--SRLEWQALRKSAAELGPLDLLKSLHHVLLEVADGEMVCPQ--CEHVYRIKDSIPNML Rozal11 MRLLTHNLLQC-HVKKCVEDREEFHPQFIERMI--PRLDFDALKAAMNQL-TEDELKLLHGILMQIIDGEMVCKN--CGHVYPIKDGIPNML Sacce1 MKFLTTNFLKC-SVKACLVQDEEFNPEFLLNIV--DRVDWPAVLTVAAELGDMAILNDLHTLLLQIAEGEMKCRN--CGHIYYIKNGIPNLL Salro MKLLTHNLLRS-RV----ETKEDFNPTFIVRML--DRIQWPVVVQAASQVGDQEFLKAAHHLLLEVIEGELECPD--TGRAFPIKRGIPNML Schco3 VRLITHNLLAC-HVKGCIELRDEFNPDFLRGFL--PKIEWQALVDAAKELGDDEFLQALHHVLLEVEEGVMTCPN--CGHKYPISNGIPNML Schpo1 MKLLTANFLNC-SNKKCLAIQQELKPEFLIGIM--PRIDWNALLKTTRQLG--VLLKSLHNVLLEITEGKMVCGN--CGHVYPIFEGIPNML Sorma MKVMTLNFLTC-AVKNCLAKDDEINPQLLINVL--PRIDWAALRTTSTELGDEALLKELHELLMEMMEGKLVCGH--CGHEYAVKNGVANFL Sphar MKLLTHNMLTC-HVAKCIHMEEDMNPDFIRHMI--PKIDWRALKEAADSLEDENTMNALHHILMEIQNCQLVCPNEECKRSYPVVQGVPNLL Spipu1 MRLITHNMLQC-HAKGCLESLDEYSEDFIRRLI--PKLDWNVLVHTAFALGDEAFLRKVHQVALEVKEAQMVCNG--CGHVYPIKDGVPNML Sporo1 VRLITQNLLSC-PSKVCLELVEEYNEEFLRGVL--SRLEWSGLRKSAAELGSPELLKVLHHVLLEVKEGQ--------------------ML Stehi1 VRLITHNLLAC-HAKGCIALREEFNPDFLRGFM--PKIEWNALVQASRQLGDEEFLKSLHHVLLEVEEGAMVCPN--CSHTYPISNGIPNML Tapde11 MKLLTSNFLTC-AVKSCLSQTNEFNPTFIQNIM--PRIEWPALLAVCAELGGQAVLQSLHNVLLEVREGKMTCGK--CGHVYLVKEGIANML Thetr MRLLTHNLMTC-NVGAC-QQSEEFSPAFVARML--ARLDWSGITAAAEDL-DDEFLRKLHSLLLEVVTGSLVCPH--CERKYPIDKTIVNMV Treme1 VRLITHNLLSC-HVKNCLVVRPPENQEFLKRFL--PKLEWGALVETARSLGTDDQLKALHHVLLEVEQGNMTCKG--CGHVYPISNGIPNML Trire2 MKVLSLNFLTC-AVKACLVQDEEVNPDMLVNVL--PRLDWAALRTTSSELGDDKLVRDLHHLLLEISEGKLVCAN--CGHEYAVKEGIANFL Umbra1 MRLITHNMLQC-HVKNCVELVEDFQPEFLQNII--GKLEWPAFVNTAVQLGNEEFLKVLHTALLEVQQGKMVCPN--CSHVYPIKDGIPNML Ustma22 MRLLTHNLLAC-HAKACLELIEEPNEIFIKGFL--PKLDWPALVKTARSLGDEALIKLLHHVLLEVVEGQMICPN--CSHIYQIRSGIPNML Walse1 VRLITHNILTC-AAKGCIEIREEFNDEFIKSFF--HKLDYNVLKSTLQSLGSEEFLRSLHRVLLEVTQGELVCPN--CQHKYPINEGIPNML Zygro1 MKLLTSNFLKC-SVKACLQQDEDCNPEFLINIL--ERVDWNALVQVASDLGDLAIIRDMHSLLIQIVEGQMSCRN--CGHVYYIKNGIPNLL [Cluster1867.fasta_al_trimmed; alignment length = 397] Allma1 TQDVRYWSKYRKPT-LLKELALHFAELAATVGGKVQIYHPSTHELAKSVSRF--QD-TAYSGHLRSDGKLLVAGDEGGNVNVFEMSRS-VLRAFKEHQSPVQLTRFQVMSGADDTTVKVWDIPSNACVHTFHTDYVRAGAVSRDNLLVTGSYDHTVKVWDVRLSVDHGAPVESVLPGA--NAFVSSGDNYFKVFDLVSHVSNHQKTIMTMRLLTGSLDQSVKIYN--VANYKVVHTLKYAA-PIMSLADDTHMAVGMLDGTLALRSRGSYRYFMRGAKPKLKDWDVYLKRFEYANALDVLFVVVALLEELMDRNGLDRALQGRSDDALAPLLKFLVRNVTHPYTLTTVTHVLLDIYTPVVHRSLQEALHKLAFKVTGERRTVNDLTKLVGVLDMLFA Ashgo11 TPEQRYWRQYSSTQ-LVKEHNIEFNPFAVTSSTRVQLFSSRTRQVIKTFSRF--KD-VVYSSSFRPDGKLLAAGDATGLVSVYDSPRN-LLVSIKASTHPAHVTKFTLVTATDDRVVRVWDIAYE-PTLELASDYVRSVCFVPGAMVVSGCYDGVVRLHDTRTQLNHGMSVEDIVSP---TQLVSCGGSKFKVWDLTGERGNFAKTVTCLCLLASSLDGHVKVFD-PLDGYRVKFGWKFSS-AVLSCAGNKHLVAGLSSGLLAIRTNNNFQRMMRGQQPRLRLFEKKLNQFKWAEALDSAFLTLTVLQELRKRGKIRVALYDRDETSLEPLLNWCLKGLEDTRVVADWIAVVLEMYATIIERSLEEMVVALRNKVRQEIHKCKEAQKIQGMLQILTN Aspfu1 TPEQQYWKTFKNPL-LIPSPAITQPSFTVTTGARVQIYSIRTRKLLRTITRF--DD-TVRGTDVRPDGRVVVTGDDTGTVQVFDVSRA-ILKTWKDHRQPVWVTKFSVLSASDDRTVRLWDLPSQSAARTFHTDYVRSGAYMPGSLVVSGSYDRTVRLWDPRMTFKMAAPIESVLPTG--TTLLASAENKIAVLDIVAMIQSHQKTVTALRLLSGALDGHMKVFE--TTGWNVVSGSKYPS-PILSLREDKHIAVGMQSGLLSIKTRSGWEKRLRGKRKKEQTWEYDLRKARYSAALDQVL-QLTLFTALRHRSALRAALQGRDEETLQPVLQWVHRNITEPRLCVEVAMNVLDIYSGNLGQSIDKMVERLHRRVREEVEMAHQACQTKGMLDMLQA Aurde31 SAESRYWRRFKHPV-FVKEYAVHFSPYAVTAGTRVQVYAPRTQKVVKTISRF--KD-VARGANIRHDGKLIVAGDDTGLVQIFDLSRA-VLRSLDHHKQPVHVTKFHVLSCSDDSTVCLWDIPSQSVVTTFHTDYVRSGLIASHNLILSGSYDGTMRLFDARMLMAPGTPVEQVAPSG--TVALSAAGPILRAWDLVAALSHHQKTVTSLRLLTGGLDHLVKVYD--VSNYKVVHTMRYPA-PVLALADDTHIGAGMSDGTFSVRRRGTYEYFLGGRHKKLREYDKFLKRFKYAAALDAVLTAFSLMQELIHRDGILPAISGRDDVLLEPLLRLLVKHVTDPRICCEVTSLVIDTYGLVFGQSIDRLLLQLRRKIKHELRMQRELLKVRGAMDMFFA Batde5 TDDTAYWSKLKSPV-IIKEFSVQFSPFCISSSTRVQIYSATTQSVKKTISRF--KD-VVHCASIRHDNKLLIAGDASGLVQIFELSRA-ILRTLAGHKAAVHAAEFKVLTCSDDKTCVVWDVPTQMQTSVFHTDYVRSAIAMPDNLFMTGSYDHTVKLWDTRMTMNHGSPIEAILPGG--GLVASAGGNRIKIWDILSSFSNHQKAITSLFLISGALDHHVKIVS--LEDYKIVHSLKYSA-PILSLGTNSQLVVGMSSGLLSIRQRGTYQYYIRGTKARLQSYDKLLKGFQYANALDAVLLIISMLEELIHRDGLRAALAGRDEHTLQRILSFLMRYISNPRLLTDVSNTILDIYSLVLGHSIGELLKKLKFKVHEEIQLDYRLGEVIGLMDTLMS Botbo1 SPESRYWRRFKHPV-FVKEYAVHFAPYAVTAAARVQIYAPRTQKITKTIARF--KD-VARSGNIRQDGKLVVAGDDTGLVQVFDISRA-ILRTLDEHKQPVHVAKFQILTCSDDTTVKLWDMPTQSVLHTFHVDYVRSGLVSSSNLILTGSYDATVRLFDSRMTMGGAAPVEDVLPSG--TTALSAAGPILRAWDLVAAMSNHQKTVTCLRLLTGGLDQMVKVYD--VSTYKVVHTMRYPA-PVLCLADDTHIAAGMSDGTFSIRRRDTYEFFLGARKKRLRQYDKLLKAFKYSAALDSVLTKFSLIAELIHRDALKAALGGRDDVLLEPILHLLVRHVSDPRMACDVAGVVIDMYSSVLGQSIDALFVRLRRKVEQELKFQREVVRLRGALDMILA Botci1 TPEQRYWKGFRSQQ-LIPSPTISFPPFCVTTGTRLQIYSIRTRKLVKTITRF--SD-VAHSGEIRRDGRVMVAGDETGKIQVFDVSRA-ILKTWEEHKQPVWTTKFTLMSASDDRTVKLWDLPSQESTTTFHTDYVRSGAFMPGSMILTGSYDETVRLWDPRMTFKHAAPVETVLPSG--TTVLAAADNQISVLDLVAIIKNHQKTVTSLRLVSGGLDGHVKVFE--TTGWNVVTGLKYSA-PVLSVNEDKHLVVGMQSGVLSIKTRSGVEKRLRGTKRKAPEWERELQLGRYHQALDCVLTVLTLLTALRHRSAMRAAFEKRDETTIQPIFKWVSKHITDPRICTDAAMLLLDIYAEYTSESLERQIKFLHRRVKAEVERSQKAMQVKGMLDLLVA Caeel DEDVIYWKRMQQLT-VFQEPAVRISPVATTSSVRLTLYDTVVCEPLNLFSRF--KK-GVCSIDFRHDGRLLAIGGDEGKVRIFDVSKV-ALRVMQASQSTVKSVHFTVFSMADDGKIKQYRVVNAVPIIEIHEDAIRCGAVSSINIVLTGGYDHKVRLWDIRLELDCEHPVESVLPGE--QLIATAAGPIVKIWDTTTALQAHYKTVTSLCLLSAGIDRRVNAFR--TTNYSLINSWSMPS-PVLDIDDDQTMAIGMGN-LLALYRRAPPVKLVEKDKLKIPKIDGMLSNFKHAAVIKLLFAVVSYLRVIVMRGAIHRALAGQERSVQKNILVFLNHNLYKAQTLKEVVNAFFDVYA--LEKLVVKHVQSLRGSLGRELEVQKMISSLIGSIDLIVS Canalb1 TPEQRYWRSYITPQ-LIKENHIEFNPFAIASATKIQVFSSKTRQVIKTFSRF--KD-VVYSGNYRYDGKLLVASDASGLVSIYDSPRN-LLVSLTPSSHPTHVAKFQLITGSDDRMLRVYDITSNGPIIQFHEDYIRSVNFIPGDLIVTGCYDGNVRILDVRAKFDQENPVEDILSS---NTLVSAGGPYVKIWDLNRQLNNFNKSTTCLGLMVGSLDSTIKVFDYTSTNWQVQFGWKFGS-GVLSCGNQKHFVAGLTSGLISIRTKGGYARMMKGITNK----------------------TNKSVNEL------------------------------------------MSSYKKYLGASIDDIKPNDLKQ---EISQCLKAKEICGMLELLGV Cangl TAEQRYWRQYAATQ-LVKEHNVAFNPFAVTSSTRVQVFSSRTRQAIKTFSRF--KD-VVYSASYRKDGKLLCAGDATGLVSVYDSPRT-LLVSVAASQHPTHVTKFTLVSASDDRVTRVWDIAYE-PQLELAADYVRTLCFVPAALVVTGSYDGALRLYDTRHTLVHDQPVENVVSP---TQLVSCGGPNFKVWDLTSERANFNKTVTCLALLASSLDGHVKVFD-PLDNFQVKFGWKFSS-AVLSCAGSRHLVAGLTSGLLAIRTKNNFQRMMRGQQRRLRTFERYINQFKWAEALDCAFLTLTILQELRKRGKIRVALQNRDESSLEPLLNWCLKGIEDVRVVVDWVTVVLEMYGQVAQESLNEMVVALRNKVREEVHKAEEAQRIEGMLQLLTN Capow TSESRYWKRFKFPV-VVKEYSIHFSPFAVTSSTRIQIYSKKSNTVKKTLSRF--KD-VAYCGTFRRDGKLLVAGDESGLVQLLDPSRS-VLRTFAGHQRAVHVTRFQIMSAGDDAVVRCWDIPAERQVLALHTDYIRAGVVSPVAVWLTGGYDHMVKLWDTRMSMNHGAPVEQILPGG--GLALSAGSNQIKVWDVLATFSNHQKTITSMRLLTASLDQHVKIHD--VTDYSVTHSIKYTA-PILSMSDDTHLVVGMANGLLSIRHRGTYRYFVRGRKRRLKPFEVFLKKFQYQNALDAVLIVISLLEELVHRDGLRIALAGRDEITLEPLIVFLIKNIANPRLLIDLSNMLFDIYTPALGQSIDELFVKLQRVIATEIAFQKQLYQLIGSLDMILS Catan2 TSDMRYWSKYRKPT-LHKESSLHFAELAVTVGSKVQIYHPSTHDVAKTITRF--SD-LAYSGHLRADGKLLVAGDEAGGVSVFEMTRS-ILRSFGGHAGPVHLTRFQVLSGSDDKTVRVWDIPSNSVVTCFHTDYVRAGTISTSNLLLTGSYDHTVRLWDLRMTMSHDSPCESVLPGS--TAVVSSGGPYFKVFDLVAHVSNHQKTITAMRLLTGSLDHSVKIYN--VANFKVVHTLKYQS-PILSLANDTHMAVGMVDGTLSLRSRGSYRYFMRGKKPKLNAYDVYLKKFEYANALDVVFVIVSLIEELLDRNGLDRALQGRTEESLGPLLQFLMRNITHPYTLATVTHTLLDIYTPVLARSLQSQLKKITEKLAEERRVVTDLTRLVGALDMVMA Cioin TQDYNYWRSLQFPI-IVKEYGVEFQPFAVTASSRVELYSKESNEVVKTFSRF--HN-TAYGASFRSDGKLLVAGNEDTQVRLFDVGRV-PLRIFKGHSRPVHVTKFQLFSASDDKTVRVWDISTEQTLNEFHEDYVRCGCISTASTIVTGAYDHTVRMFDTRITINHGCPVESVLPSG--SIILSAGGHSIKVWDALQTVSNHHKTITCMRLLSGSLDRHVKIYD--VTNYKVVHNIDYAG-SILSMANDETLVVGMADKMLSIRHRRKQKSMMRGQKQHLAKYDQYFRKFEHSKALDAALITVAVLQELIRRDTIRASLSGRTGNKLVVLLKFLCRNISNVSTLLKVCELLLDSCLETIENVVSHLFKRLQNIMHSESLLQVEMTKLLGSMDLILS CocheC53 TSEQKYWNSFASELRLDPSQHISTP-FAVTTGSRVQIFSSKTRKVVKTISRFGVDD-IAHSGNIRRDGRILVAGGDSGVIQAFDVSRA-ILKTWKEHKQPVWVTQWGLMSCSDDRTVRLWDLPSEKSTMKFHQDYVRSGTFMPAQLLVSGSYDQTVRLWDSRMVFKHAAPIETVLPSG--TAVLAASDNTISVLDIVAMLRNHQKTVTALRLLSGALDGHVKVFE--TTGWNVVGGLKYPS-PILSLNEDRHIAVGMQSGLLSIKTHKGWEKRIRGKITNGQPWAHALRKGMYAQALDMALASITLLTALRHRSALRIALSNRDSQSLQPILRWCIKNISDYRLTTDVALVVLDLYADQLGRSVDDLVLALMQRVKVTVEASQDAWKVRGMLDMLVS Coere1 -PEAGYWKKFQSPV-LVKEYGLEFSPLLVTASMRLQVYNSRTSQLKKSITRF--NG-VAHSGSYRSDGKLVVAGDDKNMVQVFDGSRA-ILRTFKGHTDPVHLTKFNVLSGSDDKTVQVWDIPSQAAVNVFHTDYVRSGSVFSGNLVATGSYDHTVRIWDLRTTISTDDPVEDVLPGG--GVIAASAGPNVHLFDLLMTMGNHEKTVTSLRLVAGSLDHHIKIYD--VQSFKMMFSMSYPA-PVLSVADDTRLAVGMASGVFSLRRRGSRAYFQRGRKRSLADYDELLRKFEHSRALDAVLTVVSLLQELIHRDGLVGALAGRDELSLDPIVRFLVKFIDHPRVLITVAETLLDIYGDLLYQSISELLMRLRAKVRLELRLQQDMTMLLGSMDMLMA Conco1 VNITEFWKNFKSPT-VLKETGLHFSPLAVTAGCKVSIYNTFTNSLVKSISRF--QD-LAYSGTIRDDGKLMVAGDASGVVQIFDLSRS-ILRTFKGHNGSVPCTKFQILTASYDKTVKIWDVPSQSPIISFHEDYIKTAVVNPSNQIISGSYDHCVKLWDIRSTINHQAPIESIEGNG--GMIAVGGGPSIQVYDLISTLDNFQKTVTSVFLMGGSLDRYVKCYD--TSDWSLCNSVKFPG-MVSAIDDNTHMVVGMTTGIFSIQTN---------RAAKYYQFDHLLRKFKYKEALDAALLGFGLISELIRRGGLISALSGRDDVSLQPIIAYLARNLRNHTLIIDVTQLVMELYGDVVWKSLDAQLRRLMTSIYNEKKLVQNLIQFQGRLGMVLS Conpu1 SPESRHWRQFRHPV-FIKEYAVHFCPYAVTAATRVQIYAPRTNKLTKTISRF--KD-IARSASIRNDGKLLIAADDTGLVQIFDVSRA-ILRTLDSHKQPVHVAAFQALSCSDDTTVKLWDVPSQAALLTFHTDYVRSGQVAPHNLILTGSYDATTRLFDSRMLMGG--PVEQTAPSG--TVALSAAGPIVRVWDLVGAFSNHQKTVTSLRLLTAGLDQMVKVYD--VSSYKVVHTMRYPA-PLLCLADDTLIAAGMSDGTLSVRRRGTFDTFIDGRRKRLRDYDRLLKGFKYSAALDAVLTSFALIQELVHRDGLRSALAGRDDVLLEPILRLLLKHVADPRLVCDVASLVIEMYEPVLGQSIDTLFVRLRKKVQAELRFQKELRKTRGALDMVFA Copci SPESRHWRQFKHPV-FVKEYAIHFSPYAVTAATRVQIYAPRTQKITKTISRF--KD-VARSGNIRADGKLVVAGDDSGLIQIFDISRA-ILRTLDSHKQPVHVTKFRVLSCSDDNTVKFWDLTSQTAISTFHTDYVRTGQVSTSNLILTGSYDGTARLFDSRMVMGEKAPVEQVLPSG--TVAVSSAGPILRVWDLVAAMSNHQKTVTALRLLSGSLDHMLKVYD--VSDYRVVHTMRYPA-PLLCLADDSHIVGGMSDGTLSIRRR---------RQKRLKNYDKYLKNFKYSAALDSVLTVFSLIQELIHRDGLKVALAGRDDVLLEPVLQLLIKHVADPRTVCYVAGIVLDMYRPVIGQSIDSLFLRLRKKLAMELRFQKELLKAKGAISMILT Croqu1 QTEGRYWRDFKNPV-FVKSYAITFSPYCISSGTKIQIYSPKTLRVVKTISRF--QL-PVRFSDIKSDGKLIVSSDDSGLVQVFDLSRA-ILRSIKDHKQPVHVSRFSILTCSDDSTVRLFDLATSKTLRTFHSDYVRAGNFL--GLVLSGGYDGKLNLWDDRWSLDHEDPIENILPSG--TLGVSAGGPVARVWDLLGSLRNHQKTITSLRLLSGGLDGLVKVYDIATGSYKVRHTIRYSS-PILSMGGDGLLVVGCTDGSLSIRKRGSETVWGRQRKQKLPVWDRMLKAFRYGDALDSVLITFSLCRELIHRDGLHQALAGRDEVSLAPILRFLAKYITDPRIGSDVLKCVIELYEPVLGKSIDALFTTLFHRVSEEIKLNFILFEINGQLEMILS CryneH991 NPHSRHFHSFRHPL-FIKHPAIHFCPYAVTSSTRVLIYAPKTGKVVKTITRF--KD-TARSGEFRKDGKLVVAGGDDGVVQVFDVSRA-ILRTMKEHNQPVRVAHFQILSASDDTTVKLWDLSTQACLSTFHTDYVRSAIFSPSDLILSASYDSTIRLHDVRITMRHGAPVEDILPSG--GVAVSVGGPILRVWDLAMALSNHQKTVTSVRVLTGGLDNMVKVYD--VEDWKVVHTMRYPA-PVLSLADDTHIAAGMTDGTLSVRRRGAYEYFAD-RQKRLRDFDKYLKSFKYSAALDAGLTAFALIQELVHRDALRIALSGRDDVTLEPILNFLARNVTDPRMAAQVVGIIIDIYTPILGQSLDEMLGKIQTRVERELSFQRELMKLRGALDMTLS Crypa2 TAEQRYWKTFKNQK-SHTTTAISFPSFAVTAGPRVDVYSIRRREPLKTIGRF--DS-VARSGEIRADSRVLVAGDDSGKMQVFDVARAVVLKTWHVHKQPVWVTRWTLMSASDDRTVRLWDLPGQEATRQFHQDYVRSGAFMPGGMLVTGSYDATVKIWDARLTFKHAAPVEEVLPTG--TTVLAAADNAISVLDLVAVITNHQKTVTSLRVVSGGLDGHVKIFE--TGSWNVVAGAKYPS-PILSLSADRHLAVGMQSGVLSLKTREILTRSL--RPAKERQWQYDLRHGKYAAALDGVLNVLTLLHALRHRSALRAALEHRDEVSVRPVMHWISNHIIDPRACVDVGLHLLDLYAEHAGASLAAAFKTLRKRVTQEVEKAQVAAQTGGMVEALMI Debha1 TPEQRYWRGFSNPQ-LVKENYIDFNPFAVTSSTRIQVFSSKTRQVIKTFSRF--KD-TVYSGQYRYDGKLLVAADASGLVTIFDSPRS-LLVSLNPSSHPTHVAKFQLITGSDDRIVRLYDITTKGPITEFHGDYIRSANFIPGNLITTGCYDGIVRIFDTRAKFNQGNPVEDLLSP---TTLVSAGGPQVKIWDLTRELNNFTKTATTLGLLVGSLDGHVKIFDSSSSNWDVKFGWKFGSGGVLSCGNHKHFVTGLTSGLISIRTRNAYNKMMRGQTKKLKQFEKHLNAFRWSEALDSAFQTVTVLNELKKRGKIRISLYGRDEISLLPILQWFIKNLEDVRLICDFIGVMLEMYGTLIDKSLEESFATLLKRINIEIKKCKEANEIGGMLELLTV Dekbr2 TPEQRYWRGFTNSQ-LVKEHNIAFDPFAVTSSTRIQVFSSKTRKVVKNFTRF--KD-TVYSGEFRHDGKLLVAGDASGLVQIFDAPRS-LLVTLQPSTHPTHVTKFQLLTCSDDRVARLYDITEE-PLMSFHQDYVRSGIFIPG-LVATGCYDNVVRLFDCRLTMNQEAPVEDLLNS---TTLLSCGESGIKCWNLAATMNNFTKTVTCLGILAGSMDGHVKVFDTASENWDVKFGWKFGS-GVLSCGNQKHLVVGLNSGLLTIRTRHAFARMIRGNNRKLKQFERDLNAFKWSDALDHSLLTVTCMEELRKRGKIRVALSGRDASTLEPLLTWCLKTIDDPRLIADYLSCVMDMYTDLIERQLEDLVSSIEEKVDLEIQRCKEARRIMGMLELLSV Dicdi GDS---WKKYSSMI-TRVESNVTFGNIITSNSKKV---------EEREITSF--RD-TPYGASYRDDGKLIVVGGEDPIIKLIDVSKN-TLRKFQGHTGGIQCTRFSLISGSNDNTVRTWAIETGEQLQMVHKDKVHCMTRHPTNIWMTGGYDHCVKLWDIRITLDHGAPVEDLIASG--TMAISVGGNYFKVWDLLNQGTHSMKSLTSIRFITSGLDHTVRVFS--TQSYSLINSYEFSE-PLLSLTNDRKIIAGSAKGTLFYARK---------GIYKSSHLDRLLRKFEHKTAFDTAVFIFKVVCELSRRDALDIVLKNREVSELDSILQMVNKLVNTIKCGILLLEKIVEFYHPSIFQEIISTMNSIKINLIKEQKKQSQLLELSGALDLLYS Dmel TPDTVYWDRLAKPE-LLKEHNLDFSPFVVTCSVRVQIYNLVTMLVVKNLSRF--QK-TAYGATFRQDGRLLAAGDEEGHVKLFDTSRN-ILRLFKGHTAPVHRTFFQLASFGDDKSVRLWDVANEKVVQTYHTDYVRAGAMHPQAMFVSGGYDGKIKLYDTRRTLDHGAPVESMLPNG--SIFVSAGGSQVRVWDLISMMSQHHKTVTCLRLLSGGLDRHVKIYD--VSTYKTVHTLTYPN-AVVSMAGDQAVVAGMVDGLVSIRRMRARKYFVSTKGPGLKSYDVHLRQFNHKKALDDVMLIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRPLMMAASTVLDVFEQRLVAYLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIG Enthi ELEGKYWDDFT----PVSSYTIRFSPFAVCSGMNVFVHSS-TESQPKVITRH--KD-FVYTCEYRNDGALISTGCADGKVRVFDSNKT-LLRTLSGHSAAVRTVCWMLYSSGDDMVVKAWDFTTKSVIGSYHTDSVRSIVQCPTNLIASGSYDHTVVLYDTRNVFKHKNPVEDIVPVG--TLIAVANGQMITVWDSTTDYSYHTNLVTNIRLFSSSLDCSINVYE--TTNYSKLHNIVYPS-PILSFDDSTAFSVGLTNGEVILFAKSSAKYFFQG-----------IRKFDYDDALDKALIIISVIREILYRNGLKIALSRRDENTLEPLMTFLINTLPSPLILVEVMSQLLDLYAQDLGKSFDEMFFKMQKRLEKEIQLNKNMQQLLGQIDLIIG Falba TEESIYWRKYRFPV-LVKETGINFSPFAVTSGMRVQIYSQSNQAVRRSISRF--GD-VAYSGSYRRDGSLLVAGSEDASVQVFHTTRV-ILRTYKAHLGPVRATAFTVISASDDRTVKLWDLPKQEFTTTDHSDYIRTMVPNLDNLFLTGSYDHTVKLWDARMTMEHGAPVECVRPGG--SVALSAGGDHWTAWDMAAQVRAHKKTVTGLRILSCSLDHTVKIHD--VRDYSVTHSVVYPA-PLLSVADNTHLVAGMANGLLSIRHRGSYRFFVRGRRPRLQPFERLLKNYEYQAALDLVLVVISLLEELVQRSALQQTLLNRSDTDLLPLFQFIIRHIDNPRLLIDVASMLLDLYDINAGKSLDDMLVRLSSRVAAELQTQRRLFSLIGSLDMLFA Fomme1 NPESRYWRQFRHPV-FVKEYAVHFSQYAVTAASRVQIYAPRTQKVVKTISRF--KD-VARSGCIRRDGKLVLAGDDSGLIQIFDISRA-ILRTFDEHKQPVHVTKFQFLSCSDDTTVKLWDVPSEASVTTFHTDYVRAGQVAPSNLILTGAYDATVRLFDARMTMGGAAPVEEVLPSG--TVALSAAGPILRAWDLVAALSNHQKTITSLRLLTGGLDHMVKVYD--VSTYKVVHTMRYPA-PILCLGDDTHIAAGMSDGTLSVRRRGAFESFLGTRKRKLRAYDRLLKNFKYSAALDAVLTAFSLIQELVHRDGLRIALAGRDDVLLEPVLKLLVKYIADPRLAGSVASVLLDMYAPVLGQSIDALFVRLRKKVDEELRFQREILKVKGALDMIFA Fusgr1 TAEQRYWKTFKNQI-LIPSPTIS---FAITTGTRIQIFSNRTRKLLKTVTRF--AD-VARSGELRRDGRVLAAGDDTGKIQVFDISRA-ILKTWAHHKQPVWTTKFTLLSASDDKTVRLWDLPSNDPTATFHSDYVRCANFMPGTMIVSGSYDSTVKLWDPRMTFKHAAPIEDVLPTG--TTVLAAAGESISVLDLVGMITNHQKTVTALRLISGGLEGHVKVFE--TTGWNVVSSTKYQS-PVLSVKSDRHLAVGMQSGVLSVRTRVTAAKKL--HKKKERSWQSDLRHARYACALDLVLNVLTLLLALRHRSALRDALESRDEHTVQPILKWVCGHICDPRVCVEVGLHLIELYAEFAGGSLQEGFRTLYRRVKAEVERAQSACQTGGMLESLMA Galma1 TAESRYWRQFKHPV-FVKEYAVQFSPYAVTAATRVQIYAPRTQKLTKTISRF--KD-VARSGCIREDGKLVVAGDDSGLIQVFDISRA-VLRTLDSHKQPVHVTKFHVLSCSDDTSVIFWDVPSQTPITTFHTDYVRSGQVSSSNLILTGSYDGTVRLFDTRMTMATQVPVEQVLPSG--TVALSSSGPILRVWDMVAALSNHQKTVTALQLLTGSLDQMVKVYD--VSTYKVVHTMRYPA-PLLCLADETHILGGMSDGTLSVRRRGVFAIF---TSRKSKEYDKLLKNFRYSAALDSVLTTFSLIQELIHRDGLRIALAGRDDVLLEPILRLLLKYVVDPRLAADITGIVLDMYTPVIGQAVDALFLRLRKKVAGELRFQEEIIKTKGALMMVLS Ganpr1 TQS--WWRGFKSPL-LIKEHAIHFCAFAVTAGARVQIYSSATCGLKKTISRF--TE-TAYGACIRSDGKLLSAGDNSGVVQLFDLSRA-ILRTYREHQGPVRVTKFQILTGSDDTTVRLFDIASESAVSVFHGDYIRSLAICSDNIFVSGSYDHTAKLWDTRMTLTHGHPIESTLRSC--SAVVTAGSAEVKVWDIVAVLANHQKTVTALYVLSGSLDGHVKAYK--VADWSVEHSIKYST-PVLSLADGTRLVAGSSTGVLSIRRRGAV------RQLRLAPYDKLLKSFHYAKALDTVIIVTSVLEELIHRDGIRTALVGRDEVGLEPLMRFLLKHITNPRLLVGVAEMVLDIYSPVVNHSIGDLLAKIRTKVRAELELQERLIALEGTLDLLLM Gloin1 TNESRYWKGFKTKV-KLKEIAICFSPFAVTSSTHVQVYSSKNYQVTKSISRF--ND-IAYSGNIRNDSKLLVAGDATGLIQIFDISRA-ILRTMKGHKLPVQITKFQILSCSDDKTVKIWDISGQEPVSVLHQDYVRAGLISNDNLVLSGSYDQTVKLWDLRMTLTHEMPVEEVLPSG--GTVISAGGPIIKVWDINGSISNHQKTVTSMRLLTGSLDHHVKVYD--TKNFEVVHDLTYSD-PILSLADETHIVAGMTSGSLTVRIRGTYQYFIRGRKERLAKYDKYLKNFQYSNALDAVLLTVSLIQELILRDALAIAIAGRDETSLAPLIKFVNTWITDPKLMIDVSQVILGLYSPVIGQSITKLINILHQKVKNEISLQKEIAKVIGSVEMIFA Hisca1 TPEQQYWRSFKNPL-LLPSPSISQPSFTVTTGARVQLYSIRTRKLLKTITRF--DD-ISRCASVRADGRVLAASDDGGTIQVFDISRA-ILKTWREHKQPVWAVQFALVSASDDRTVRLWDLPSESSVRTFHADYVRCAGFMPAALLYSGGYDGLVKVWDSRMTFKMRAPVESVLTAG--TTVLAAAENKIAVLDVVAVIKSHQKTVTALRLVSGALDGHMKVFE--TTGWNVVGGSKYPS-PILSLGEDKHIAVGMQSGLLSIRTRKGWEKRLRGKRKREQPWELDLRKGRYAAALDAVLNTLTLLTALRHRSALRTALSGRDEVTLQPVLQWVYKSITDPRMCVEVAMNILDIYSGNLGQSFDGMVEKLHARVREEVDRAQQAWMTKGMLGMLSV Klula1 TPEQRYWRSYSSTQ-LVKEHNIAFNPFAVTSSTRVQVFSSRTRQVIKTFSRF--KD-VVHSATFRQDGKLLVAGDATGLVSVYDSPRT-LLLSIQASSHPTHVTKFTLVTANDDRVVRLWDVAYE-PTLQLASDYVRSVCFVPNAMVATGSYDGVVRLYDIRTTLDHGLPVEDITSP---TQLASCGGNGFKVWDLTSERQNFAKTVTCLVLVASSLDGHVKIFS-PLENFQFKFGWKFSN-AVLSCAGNKHFVAGLSSGILAIKTKNNFQRMMRGPQRKLRQFERHINQFKWSDALDSAFLTLTVLQELRKRGKIKVALYGRDESSLEPLLNWCLKGIEDVRIVADWIAVVIELYGSVLEKSLEEMVITLKKRVREEIRKAKEAQKIEGMLQLLTN Lacbi2 NPESRYWRQFKHPV-FVKEYAIHFSPYAVTAATRVQIYAPRTQRITKTISRF--KD-VARSANIRQDGKLVVAGDDSGLVQVFDISRA-ILRTLDAHKQPVHLTRFQVLSCSDDTSVKLWDIPSQTAISTFHTDYVRCGQVSTSNIVLTGSYDATVRLFDSRMTMREKTPVEQVLPSG--TVAISSAGPILRAWDMVAALSNHQKTITALRLLTGSLDHMVKVYD--VSTYQVVHTMRYPA-PILCLADETHLAGGMADGTLSIRRR---------RMKRLKEYDKLLKAFKYSAALDSVLISFSLIHELIHRDGLKAALAGRDDVLLEPVLRLLLKYATDPRIVCTIASIVIEMYRPVLGQAIDSLFLRLRKKVIAEIRFQNELIKTSGTLAMIFS Lenti61 NAESRYWRQYKHPV-FIKEYAVHFSPYAVTAATRVQIYAPRTQKVTKTISRF--KD-VARSGCIRGDGKLVVAGDDTGLIQIFDISRA-ILRTLDSHKQPVHVTKFQVLSCSDDTTVKLWDVPSQAAITTFHTDYVRSGQVSTSNLILTGSYDATVRLFDSRMVMGDTTPVEQVLPSG--TVALSSAGPILRVWDIVAAMSNHQKTVTSLRVLTGSLDQMVKVYD--VSTYRVVHTMRYPA-PILCLADETHIAAGMSDGTLSVRRRGAFESFLGGRKKRLRDYDKLLKNFKYSAALDSVLTTFSLIQELIHRDGLRTALAGRDDVLLEPILRLLLKHVTDPRMVCDVANIVIEMYTPVLGQSIDTLFVRLRKKVTAELRFQKELVKAKGALDMLLA Malgl1 HSESSYWRQFQSPI-FLKEFAIHFVPFAVTTGTRVQIYSMRTSRVVKTITRF--KD-VARSAHFRSDARLLVAGENTGNVQVFDTSRT-ILRSFQGHQMPVHVSKFQVLTASDDRTVRMWDMPEQKETCRFHSDYVRAGVVSPENVIMSGSYDGTVRLWDMRMRMDHGAPVEDVLPTGGSGIAVSAGGPFLRVWDLLSTISNHQKTITKLRLLSGGLDHLVKVYD-PAQDYRVTHTMRYPA-PILSLADESHIAVGMSDGTLCIRKRGAYQHFADTRRQRLKRYDQLLKAFRYRDALDASLVTFALIMELIRRDGLRRAVSGRDDITLEPLLRFLLRHVTNPQLVCDTLNMIIDTYASVLGQSIDDLFGRIWAKLGEEMRLRTQLFQVNGALEMLLA Mellp23 RSESKYWRDFKNPV-FVKSYAITFSSFCISSGTKIQIYSPKTLRVVKTISRF--QL-PVRFSDIKSDGKLIVSSDDSGLIQVFDLSRA-ILRSFQDHKQPVHVVRFSILTCSDDSTVRLFDLATSKIMRTFHSDYVRAGNFM--ALVISGGYDGKMNLWDDRWTLDHEEPIENILPSG--TLGVSAGGPVARVWDLLGSLSNHQKTITSLRLLSGGLDGLVKVYDLSTGSYKVRHTIRYSS-PILSMGDDGTLVVGCTDGSLSIRKRGSETVWDRQ---GLDIWDRMLKSFRYGDALDSVLITFALCRELIHRDGLHQALSGRDEVSLAPILRFLTKYITDPRIGSDVMKCIMELYESVLGKSIDSLFNKLWHRVTDEVKLHSKLFEINGQIEMILA Mnele NPEERFWKKFKFAA-AIKEFALSFSHYTVTSGTKVNVYSVKTNAVQQSISRF--KK-TAFSGCIRRDGKLVVAGSEDNCVQVFEVTRS-ILRQLTGHVRPCHVTKFHILSAADDKTLRCWDLPTGEEVLCMHDDYIRSAATVSMCIWFSGTYDHTVKMWDKRLTLDHGSPVESIVPSG--GIAISCGSNKIKVWDVHRTLSNHQKTITCLRLLSSSLDHQVKMYD--LSTYKVTHSIKYSA-PVLAVGNNSHLIAGCNDGIVHIREHGTGAYFARGKRKKLSQYDLHLKRFQYREAFDHVMIVVSVVLELFRRDAVKRVLSGRDEETLQPVLTFLVNHVTNPRVLCDLAHILADLYSPVLGMSIDKLFEKLNKRLKFELKVQERYMKLQGAMQCFFT Monbr PAQERYWSQLRVPV-VHKENGTAYSPLAVAAGAQVVIYEARTNRVKHTLTRF--KS-DVTSVAYREDGKLLVTATRDGGVALHDAGRS-TLRRFDAHSRASFVAKFRVFSGGDDSLVKLWDVAIEQVVATFHEDHVRAGCAV-PNTFLTGSYDHKARLWDPRMTFDHGGPIESVLPHG--ALAVTAGENRLQVWDLVASVSNHQKTITDIHCFSAGLDRMVKVYD--VSDWRVLNSFKYSN-PILSLDDDSHLAVGMTAGLLSVRHRGTYRYRVRGNRPKLKAFDRHLQKFHYAAALDSVFIVASVLQELSERNALHSALGGRDESSLVPILKFCVRNIDDPRLLVMVSEVLLDLYAPGLGLSVDDYFLRLRDKVSAELQLQKQLIALQGSLELLLG Morel2 TAESRYWRKFKSPI-VVKEFAIHFSEFAVTASTRVQIYSSKTHQVKKTISRF--KD-VAYSGTIRNDGRLVVAGDATGLIQIFDVSRA-ILRTFRDHRHPVHVAKFQILSASDDKTVRIWDMPSETPMTIFHEDYIRAGMVSHDNLILSGSYDQTVKLWDMRMTMNHGAPVECVDPDG--GVVVSAGGPHLKVFDLLASLSNHQKTVTSMRLLTGSLDHHVKVYN--VQDYSVVHSVKYPA-PVMSVADDTHLVAGMAGGLLSIRQRGTYKFFVRGKKRRLREYDRYLKVFQYGNALDACLTTVSLIQELIHRDGLRQALSGRDDISLEPLAQFLVRNINNPRLLVDVTTVMINMYTAVLGQSIDELFMRLRAKVKQEIAFQKQLFSVIGSMEMLFA Mucci2 TAEAKYWKRFKSPI-VIKEFAIFFSPFAVTSSARVQIYSSKTHQPKKTISRF--KD-IAYSGSFRQDGKLIVAGDATGLVQMFDGSRA-ILRSFKAHNLPTQVTQFNILSASDDKTVRIWDIPSGESVNVFHEDYVRAGVVSQDNLIVSGSYDQTVKLWDMRMTMNHGAPVESLLPNG--GAVISSGGPVIKVWDLLSTLGNHQKTVTSMRLVTGSLDQHVKIYD--VQDYKVVHSVKYPA-PILSVGDDTHLAAGMSNGLLSIRQRGTYKYFMRGKRQRLKKYDQFMKVFQYSNALDEVLVVAAVLQELIHRDGLKQAITGRDDVSLEPLMRFLIRNIHHPRLLVDVSEAVIDCYTRVFGQSIDDLLSRLTVKVKQEIQLQKDLIETMATLDMLFT Mydma SKENKQWKLFQFPV-IVKEYSVHFSPCLVTSSAKVQIFAPYTNEIIRTSSRS--KE-NVYGARFRLDGKLMVTGGESGTVQVLDVSRA-ILRNLKGHTKPTHVCHFKVFSASDDKTVRCWDLPTEKETFVVHKDYIRSGCINPTSIFISGSYDHKIKMWDLRMEMNHGAPIECVIQNG--SLCISSGGNYINVWDIIAQFSNHQKTITSLRLLSGSLDRHVKVYD--IEDYSLVANIDYPS-PILAMDDSQHIVVGMSDGAISLRHKGTYLHRIRNFTKKLSKADRHLQKFRYHEALDCVLYVISVLTELSRRNALKVALKNRDANSLLSIMKFLVRNISCPFILVPIADLVLTMYSSIAGTNFDLMLKKLSARIKADLRTYEEMMKLLGAMEQVFT Neucr2 TAEQRYWKSFKNQK-SHTSTAISFPGFAVTSGPRVDIFSIRKRELLKTIGRF--DS-QAHSGEIRADGRVLVAGEDSGKMQVFDVTRAVILKTWHVHKQPVWVTKWTLMSCSDDKTVRLWDLPSNAPSRLFHQDYVRSGAFMPD-LLVSGSYDSTVRVWDARLTFKHADPIEEVLPGG--TTLLAATGSAISVLDLVALITNHQKTVTSLRVVSGSLDGHVKVFE--TTNWNVVSGSKYPS-PILSLSEDRHLAVGMQSGVLSLRTRAASNKSM--RRVKLKPWQRDFREGRYAACLDAVLTALSVLVALRHRSALREALEGRDEVTVLPLLKWVIKYISDPRVCVDVAFQLFDIYSEYVGGSLADQFAVMTGKVSREVEKAQMAIITNGMVESLMI Orpsp11 TNEY-YWKKFKNPI-LVKEHGIYFSPFAVTSSARVQIYSPVSHTVKKTISRF--TD-IAYSGHIRSDGQLLVAGDATGLIQMFDLSRA-ILRTFREHSKPVHVTKFQILSASDDKTVKLLDIPGQSVLNNFHKDYVRTALVSQDNIILSGSYDHTVKLWDARLSLDHGAPVESVLPGG--GLAVSVGGNYMKIWDILATLSNHQKTITSVKILTGSLDHHVKIYD--VQDFNVEHSLKYES-PILSLG----------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 TPEQQYWRTFKNPL-LIPSPAITQPSFTVTTGARVQIYSIRTRKLLRTLTRF--ED-TVRGTDVRADGRVLVTGDDTGAVQVFDSSRA-ILKTWKDHKQPVWVTKFSVLTASDDRTVRLWDLPSQTSARTFHSDYVRSGAFMPGSLVVSGSYDRTVRLWDPRMTFKMGAAIETVLPAG--TTVLAAADNKIAVLDIVAMIQSHQKTVTALRLLSGALDGHMKVFE--TTGWNPVSGSKYPS-PILSLREDKHIAVGMQSGLLSIKTRSGWEKRLRGKRKREQPWENDLRKARYSVALDQVL-QLTLLTALRHRSALRASLKDRDEVTLQPVLQWVHKNIREPRLSVEVAMNLLDIYSGNLGQSVDKMVERLHRRVRDEVEMAQQAWQTKGMLDMLKA Phybl2 SSEAKYWRRFKSPI-LIKEYAIYFSPFAVTASARVQIYSSKTHQPKKTISRF--KD-IAYSACFRPDGKLIVAGDGTGLVQLFDVSRA-ILRTFREHTMPVHVAQFNILSASDDRTVRLWDIPSEKSINVFHEDYVRTGQVSQDNLILTGSYDQTVKLWDTRMTMRHGAPVESVLPGG--GAVVSAGGPTLKVWDLLSEVSNHQKTITSMRLITGSLDQHVKVYN--VQDYKVVHSVKYPA-PVLSVANDTHLVAGMANGLLSIRQRGTYKYFMRGRQNRLSKYDQLLKKFQYGNALDEVLVVVALLQELIHRDGLKRAITGRDDVSLEPLVRFLVKNVHNPRLIVDVADVVIDVYTLVFGQSIDDLMKQLSTKVKQEISFQKDLTQTIAALDMLFT Picst3 TPEQRYWRGYTNPQ-LIKENHIHFNPFAVTSSTRIQIFSSKTRQVIKTFSRF--KD-IVYSGEFRYDGKLLVAADATGLVSIYDSPRN-LLVSLNPSSHPTHVAKFQLITGSDDRIVRLYDITTKGPVTQFHGDYIRSASFIPGNLVATGCYDGFVRLFDTRALFKQDNPVEDVLSA---TSLVSAGGPVVKVWDLSRELNNFTKTATTLGLLVGSLDGHVKIFDYTTSNWDVKFGWKFGSGGVLSCANHKHFVTGLTSGLLSIRTRSAYNRMMRGQTKKLKQFEKHLNAFRWAEALDGAFHTITVLNELKKRGKIRISLYGRDEISLLPILQWFIKNLEDVRLICDYVAVILEMYGSLIDSSLEECFANLLKRINIEIKKCREATEIGGMLELLTV Plicr1 NPESRYWRQFKHPV-FVKEYAIHFSPYAVTAATRVQIYAPRTQKITKTISRF--KD-VARSGCIRGDGKLVLAGDDTGLIQVFDISRA-ILRTLDSHKQPVHVTKFQVLSCSDDTTVKLWDVPSQTAITTFHTDYVRSGQVSTTNLILTGSYDSTVQLLDARMVMGGTTPVEQVLPSG--TVALSTAGPILRVWDIVAALSNHQKTVTSLRLLTGSLDQMVKVYD--VGSYKVVHTMRYPA-PILCLADETHIAAGMSDGTLSVRRR---------RKKRLREYDRLLKNFKYSAALDSVMTTFSLIQELIHRDGLRSALAGRDDVLLEPILRLLVKHVTDPRMVCDVAGVVIEMYSPVLGQSIDALFLRLRKKVAAEIRFQKELVKAKGALDMVFS Polpo GNAANKWDPYG--------YGITFDSMMVTFNKRVMLFNLDPKSAEKNIADY--KEHNALCANFRSDARLAAISDEQSNIKLYNLAKS-NLRTFKGHTGSVHVVKFKLISGSNDHSVRVWDIGDAEESRVIHNDQVRALCGHPTKLWLSGGYDHKVKLWDL-HTLDHGAPVEDIIKSG--AMAVSAGGTHICIWDLL-QSRNHVKTITSLKFLSAGLDHMVKVYS--TSTYRVVSTIKFND-PILSMTNHKKLYVGTTNGNIQVAIK---------SKFKCSNVDKLLKKFEHKAAFDSVLLFFKVVCELSRREALEKVLEGRDPASLKLLLDMIGKMMQSPKCGVMLVDRVLDIYKYALYED-SKQLNKLKVLVREELKRQSEFLKIAGALEILYS Pucgr2 RSEGRYWREFKNPV-FVKSYAITFSSYCVSSGTKIQIYSPKTLRVVKTISRF--QL-PARCSDIKSDGKLVVSSDDSGLIQVFDLSRA-ILRTFKEIKQPVHVVKFHVLTCSDDSTVRLFDLATSKTVRTFHTDYVRAGDFT--ALILSGSYDGQLKLWDDRWSLNHQHPIEKILPTS--TLAISAGGPVANVWDILGSLSNHQKTITSLRLLSGGLDGLVKVYDISTGSYKVRHTIRYSS-PILSMADDSLLVVGCTDGSLSMRKRETEIVWGRQKKQRLQTWDKMLKAFRYGDALDSVLTTFSLIRELMHRDGLHQALSGRDEVSLAPILRLISRHITDPRIASDVLNCIINLYRAVLGKSIDALLSTISFRISDELKLHSTLFAVNGQLEMILS Punst1 SSESRYWRQFRHPV-FVKDYAIHFSPFAVTSATRVQIYAPRTQKVTKTISRF--KD-IARSGCIRVDGKLLVAGDDTGLIQVFDVSRA-ILRTLDSHKQPVHVTKFQVLSCSDDTTVKLWDVPSQAAVNTFHTDYVRSGQVAPSNLILTGSYDATVRLYDARMVLGGKVPVEQVLPSG--TVALASAGPILRVYDLVAALSNHQKTVTSLRLLTAGLDQMVKVYD--VSTYKVVHTMRYPA-PVLCLADETHIAAGMSDGTLSIRRRGTYESFLGGRKKRLRDYDRLLKGFKYSAALDSVLTTFSLIQELIHRDGLRSALSGRDDVLLEPILRLLVKHATDPRMVCDVAKVVIEMYTPVLGQSIDSLFLRLQKKVATELRFQQELVKTRGALDMVFA Rhior3 TAETRYWKRFKSPI-VIKEYAINFSPFAVTSSTRVQVYSSKTHQPKKTISRF--KD-IAYSGSFRQDGKLIVAGDATGLIQMFDGSRA-ILRSFRGHELPTQITQFNILSASDDKTVRIWDIPTGNNVNLFHEDYVRAGVVSQENLVISGSYDQTVKLWDMRMTMNHGAPVESLLPNG--GAVISSGGPTVKVWDLLSTLSNFQKTVTSMRLVTGSLDQHIKIYD--VQDYKVVHSVKYPA-PILSVGDDTHLAAGMSNGLLSIRQRGTYKYFMRGKRQKLRKYDQFIKVFQYANALDEVLVVAAVLQELIHRDGLKAAITGRDDVSLEPLMRFLIRNIHHPRLLVDVSEALIDCYTRVFGQSIDDLLSRLTVKVKQEIQFQKDLIGTMAALDMLFT Rhoto1 QKESVYWRSFKSPV-FLKSYAVHFSPYVVTSGTRLQIYSPKTNRVVKTIARF--KE-TATSGEIRTDGKLCVAGDEGGLVQVFDISRA-ILRTIRAHKQAVHTTKFQILTTSSDTTVRLFDLSTSAPLRTFHSDYVRTASFVPSSLIFSGGYDSTVRLWDARWIGRHGKPVDQVLEQG--TMAVSAGGPILRVWDLLGALSNHQKSIMALRVLSGGLDGLVKVYD-PQENWRVRHTMRYGG-QVMSLANNSHLIAGLSDGSLSIRTR--YDAILAGRRKKLSEWDRMLKNFRYGDALDSVMTAFALMDELIRRDGLAIALANRTDVSLEPVLSFLVKHIIDPRLAADVASVLIDIYTPTLGLSIDTLFTRLRRKLDDELDFHRELTMVQGALDMVFA Rozal11 TPEDPVLKQFKKQT-IIKEFSIAVSPIALVSSSRVQIFSYHDLSVKKSIAKF--KD-VVRSVAYRHDGKLIAAADSTGLIQVIEPKST-ILRTLSSHTEAVNSIMYQLLSASDDCMIKLWDVPSQTVLRTFHTDYVRSLSTTNDSLFVSGGYDHKMILWDKNLLMDHGYPVEAVLPGH--SIAVSAGGPTVKIWDILATLNNHQKTVTCLRLYTGSLDHHVKVFD--LETYKICHSFKYTN-PVLSLALMTRFVVGMTNGLISIRQRNTKRYFARGKHKALKDYERFIKKFQYQNALDAAIVVFHVIEELALRNALVAALTGRDESRLLPVLKYLMKNVINPLVLIVVTNTVIDMYAGVFGFSIDDMLAKLRSKVKEEVELQKRMQELKGMMNLLLN Sacce1 TPEQRYWRQYTSAQ-LVKEHNISFNPFAVTSSTRVQIFSSRTRQVIKTFSRF--KD-VVYSASFRSDGKLLCAGDATGLVSVYDSPRT-ILLSINASTHPTHVTKFILATASDDRVTRLWDIAYE-PQLELATDYVRTLSFIPAALVATGSYDGLIRLYDTRYSLNHDQPVENVISP---TQIVSCGGNNFKVWDLTSERGNFNKAVTCLALIASSLDGHVKVFD-PLDNFQVKFGWKFSG-PVLSCAGNRHLVAGLSSGLLAIRTKNNFQRMMRGSQRRMRAFERNINQFKWSEALDNAFLTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRIVADWVAVVLELYGNTLESSLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS Salro TAEDRHWKKYGEPR-MVKEVGINFCAYVVTAGSHVHVYSGQTHRSKITFSKF--TA--ARSGAFRRDGKLLVAGDKAGPVKIFNITKS-PLRIFEGHRKDVRVTNFQVFSAGEEGVVKLWDIPQEQEALSISNDYITSGNTIEANLVFLGGYDHKARLVDVRLEVDHGASIECVWNNG--TMVITAGQNHISIWDVLAKLSNHRQTITGVRLFSCGLDRMVKVYD--VTNWSVVHSMKFTG-QLLSMGDDSALAVGHSNGYLGVRVRGTRRYFMRGHKRKSHPHNRLLAKFRFSEALDEVFVKVSFMHELMQREALRTALSNRDEAGLEPILSFVVAQITNPRILTHVAHLILDIYSPGKGRAIDSMFVQLSNKLKQELNLQRQLIAVQGMLDALLD Schco3 SPEARQWRAFKHPV-FVKEYAVHFSPYAVTAATRIQIYAPRTQKVVKTISRF--KD-VARSGHIRADGKLVVAGDDSGLVQIFDISRA-ILRTLDAHKLPTHVAQFQVLTGSDDTTVRLWDVPSQTPVSTFHTDYVRTGTVSTTNLIFTGSYDGTARLFDARMSMRPAPPVEQAAPAG--TVALTTAGPVLRVWDLVAALSNHQKTVTALRVLTGGLDRMVKVYD--VASYRVVHTMRYPA-PLLCLADGTHLAAGMADGTLSVRRRASYEAFLGGRRKRLRDYDRMLKAFKYSAALDAVLTTFAVIQELAHRDGLRSALAGRDDVLLEPVLHVLLKHVADPRLVCDVARVVLDMYAPALGQSIDALVLRLRRKVAAELRFQREVASVRGALDMLLA Schpo1 TAENKFWRSFKVPV-VAKEYSIHFSAFAVTSGARVQIYGASSRSVKKTIARF--KD-TAYSGNIRKDGKLLLAGDATGLVQIFDLTRS-ILRALDAHQFPVHVTQFTFLSGSDDKTVKVWDLSTGAVQYDLHEDYVRTA--SWMSRLVSGGYDGTIRLWDTRMSFSHGEAIDVVLQSG--STVISAGGPSIKVWDLVAKLSNHQKSITCLRLLSGGLDGHVKIYN--ISDWKVVHGMKYSG-PILSMGDSCNLVVGMSNGTLSQRTR-----FLGGRRKRLRPFDKALKSFCYSDALDMVLLIITMLIELLHVGGLRIALSNRDDLSLTPLINFLRKYIRDPRTLCIVTSTILDIYGAALGGSVENAISKLREKVEQEVAVTQRANELVGMLQMLSA Sorma TAEQRYWKSFKNQK-SHTSTAISFPGFAVTSGPRVDIFSIRKRELLKTIGRF--DS-EAHSGEIRADGRVLVAGEDSGKMQVFDVTRAVILKTWHIHKQPVWVTKWTLMSCSDDKTVRLWDLPSNAPSRMFHQDYVRSGAFMPD-LLVSGSYDSTVRIWDARLTFKHADPIEEVLPGG--TTLLAATGSAISVLDLVALITNHQKTVTTLRVVSGSLDGHVKVFE--TTNWNVVSGSKYPS-PILSLSEDRHLAVGMQSGVLSLRTRAVSNKSM--RRVKLKPWQRDFREGRYAACLDSVLTALSVLVALRHRSALREALEGRDEVTVLPLLKWVIKYISDPRVCVDVAFQLFDIYSEYVGGSLADQFAVMTGKVSREVEKAQMAIITNGMVESLMI Sphar TAETRYWRKFKFPI-TVKEYGISFCNFAISSSTRVQVFAANTNKVKKTVSRF--KD-VAHSPHIRDDGKLMVAGDDSGLVQIFSMSRE-VFRQFSTHIRPVRWTRFGVVTGSDDMTVRGFDIPSGEETFCLHSDYVRCGAVNPASLVLSGSYDHTVKLWDTRMTMDHGAPVEDVLPGG--GMVVSCGGNTIKVWDMLMSFSNHQKTVTSLRLLSGSLDHHVKIYD--VKNYKVVHSIKYSA-PVMSLAEDTHLVVGMADGTLSIRHKGTQQYFKRGRKKGLAEYDVFMKKFQYGLALDAALIIVSLIEELAHRDGLKIAISGRDEAALTPLLVFLLKHVNNPRLLIEVTNMVLDVYARVLGKSIDELVLKLRNKVHQELEFQKRLMELSGAFELILA Spipu1 TAEATYWRKFKSPV-LLKEYAIHFSPFAVTSSTRIQIYSTSTQSVKKTISRF--QD-TAYSGHIRGDGKLLVAGDASGLVQLFDLSRA-ILRTMRGHDGPVHMTRFQILSGSDDNTVRVWDVATETPLAVFHEDYVRTGLVSTENLVLSGSYDHTVKLWDLRMTMRHGFPVESLLPGS--GLVASAGGNQIRIWDILGTLANHQKTITCMRILTGSLDHHVKVYS--ARDYKVVHNIKYPA-PIQSIGNDTHLVVGMNNGLLSIRQRGSQKYWNRGKGKQLKSYDKLMRRFRYADALDASLIVISVLEELRHRGGLRAALGGRDDKSLEPVLRFIMKHISNPRFLIDIANIILDMYEGVLGQAIDELIARIRKKVAQEIQLQERLNEVMGFMMTLLS Sporo1 ---------FQSPI-FLKSYAVHFSPYVVTSGTRLQIYSPKTNRVVKTISRF--KE-TATSGEIRGDGKLCIAGDEGGLVQVFDISRA-ILRTIRAHKQAVHTTKFQILTTSSDTTVRLFDLSTSQPLRSFHTDYVRTASFVPSALVFSGGYDNTVRLWDSRWVGRHGKPVDQVLDQG--TMAVSAGGPIMRVWDLLGALSNHQKAITSLRVLSGGLDGLVKVYD-PQDNWRVRHTMRYGG-QVMSLANNSHIVAGMSDGSLSIRTR--YDALLAGRRRKLTEWDKMLKNFRYGDALDSVLTTFALMEELIHRDGLPIALANRDDISLEPVLSFLVKHVTNPRLATDVANQLIEIYTSALGLSIDTLFTRLRRKVDEELEFQKELTQVRGALDLIFA Stehi1 SADSRYWRQFKHPV-FVKEYAVHFAPYAVTAATRVQIYAPRTQKITKTISRF--KD-VARSGSIRADGKLLVAGDDSGLIQIFDVSRA-ILRTLEGHKQPVHVTKFQVLSCSDDTTVRLWDVPSQSPITIFHTDYVRSGQVSTTDLILTGSYDGTVRLFDTRMLMGASTPVEQVLPSG--TVALSSAGSILRVWDLVAALSNHQKTVTSLRVLTGGLDHMVKVYD--VSNYNVVHTMRYPA-PVLCLADDTHIAAGMSDGTLSVRRRGTFESFLGGRRKRLKEYDRLLKTFKYSAALDSVLTTFALIQELIHRDGLRSALAGRDDVLLEPILRLLLKHVSDPRMVCDVAGVVIEMYTPVLGQSIDTLFLRLRKKVAAELRFQKELVKAKGALDMVFA Tapde11 SAESRYWRKYKSPI-IVKEYAIHF--FAVSASTRIQIYSSKTRSVAKTISRF--SD-ITFGAEFRKDGKLLVSGDATGLVQIFDASRS-ILRSIDIHKLPTHVSKFTIITASDDKTIRIWDIPTQKPINTFHTDYVRTAEFMTSSLYLSGSYDGTVRLWDARQTLSHEANVERVL-SG--TTVTSAGGSDVRVWDLSSILQNHAKGVSCLRLLSGGLDGHLKIYD--TTEWKVLHSVKYPH-PILS--DDKHLVVGMSNGLLSIRTRATHRPTL--RGPGLRKWDKCIRRYAYADALDAVLTIHAVLSTLKRRSGLIQALSQRDDTSLVPILRFLIRQIKDVRLCIDVTMVVLELYGGALGASTGVLLYRLDEQVRGMVGRAKEAVKVDGMLQMLFV Thetr SSEARWWKRYKAVA-TEKKFGIEFSPFAVTAGSRVHVYSAATKAETRTLTRF--PD-TAYCGTWRGDGKILAAGSEDGLVQLFDASRL-ILRKLKGHTRAVRALGF-LYTASDDFTARIWDVPTETSTMTLHTDVVRSATLMPGSLLLTGSYDHSIMLWDTRLSLDGGGPLEALLPSS--GLVVSAALNSLSVWDILASVSNHRKTITALRLLSASLDQQVKVYD--VTDYSVTHTIKFES-PLLSLADNSLLVAGGVNGELAIREHGSHAHAERGRRKKLRDFERFLKKFEYKNALDAALVVVSLIAELKQRAGLNIALKGRDDTSLEPILEFLIRYAVVPRLLLDVAATVLEMYAPFIGQFLDEQFVQLAQQTRREVAFLRDLHSMQGMLEVFLE Treme1 NPHSRHFHSFRHPL-FIKHPSIHFCPYAVSSSSRVMVYAPKTGKVVKTISRF--KD-TARSAEFRKDGKLVVAGGDDGLVQVFDVSRA-VLRTFNGHNQPVHVTKFQVLSASDDKTLKLWDLSTQSCLTTLHTDYIRSAIFHPTSLLLSGAYDSTFRLHDIRITMRHGMPVEDILPSG--GVGVSVGGPILRVWDLTMALSNHQKTVTCARVLTGGLDMMVKVYD--VEEWKVVHTMRYPA-PLLSLADDTHIAAGMTDGTLAVRRRGSYEFFTD-RKERLRDFDKYLKAFKYSAALDAGVTAFALMQELIHRDALRIALSGRDDVTLEPILGFLLRYVTDPRLVSDVVGVIIDIYTPMLGQSLDETMAKLNQRIGMELKFQHELMRLRGALDMTLA Trire2 TAEQKYWKSFKNQL-LIPSPTVS---FAVTTGTRVQIYSIRSRKLLKTITRF--TD-VARSGEIRKDGRVLVAGDDTGRIQVFDVSRA-ILRTWLDHKQPVWTTKFTVLSTSDDRTVRLWDLPSSEPTSTFHTDYVRAGSFMPGTMVVSGSYDSTVKLWDPRMTFKHAAPVESVLPTG--TTVLAAAGNAVSVLDLVALITNHQKTVTSMRLVTGSLEGHVKMFE--TTGWNVVNSFKYQA-PILSVCDDRHLAVGMQSGVLSIRTRIEASKRL--TRKKERPWQADLRHARYAKALDQVVNVLTLLLALRHRSAMRDALENRDEQSVQPVLKWVCGHICDPRVCVEVGIHLLDLYSEYAGASLLQGFKTLHRRVKVEVERAQLACQSGGMLESLMM Umbra1 TNESRFWKKFKSPV-SIKEYAINFSPFVVTSSTRVQIYSSKTHQPKKTISRF--KD-TAFSGTFRHDGKLVVAGDATGLVQVFDVSRA-ILRQFNGHKLPVHVAKFHVISGSDDKTLKVWDVSTSEALNVFHTDYIRAGLVSVENLVLSGSYDQTVKLWDLRMSMNHGAPVEEVLPGG--GAIVSAGGTTVKVWDLLSLVANHQKTITSMRLLTGSLDQHVKIYN--VMDYKVVHSIKYPA-PVMSVGTDSTLAVGMSNGYLSIRQRGTYKYFVRGRKKRLQPYDQYLKKFQYGNALDEVLVVVSLLQELIHRDGLKLAIAGRDDISLEPIVRFVVKHINYPRLLIDVANAIIDMYSSALGQSIDDLIGRLRDKVKMEIAFQKDLMQTLASMDMLFA Ustma22 SPESNYWRKFRTPV-FVKELAIHFVPFAVTTGARVQIYSMRNSRVSKTISRF--KD-VARSASFRSDGRLMVAGDDSGLIQVFDTSRA-ILRTMRGHSGPVHVTRFEIMSAADDRTVRLWDVPEQKAVHVFHNDYVRSAVFSPDNLMLSGSYDSTVKLWDSRMTMNHGASVEDVLPTGGGGVALSAGGAVMKVWDLMMSISNHQKTITSLRILTAGLDHLVKVYD-PAQDFKVTHTMRYAS-PILSMADESHIAVGMADGTLCVRKRGAYEFFMQGRKRKLQDYDRFLKAFRYSDALDAALVTFGLILELIHRDGLRRAISNRDDVTLEPVLRFLLRHAANPSLVCDTLNVIVDTYASVIGQSIDDLFGRIWAKVSDELRLQRDLMQVRGSLEMILA Walse1 SQDAKYFKSFK-ST-FVKEFAVSFSPFAVTSATRVQIYTPRSQSVVKTISRF--KD-VARSGQIRSDGRLVVAGDDSGLVQVFDISRA-ILRTFEDHKQPVHVTSFKVLSASDDCSVILHDIPSQSALQKFHSDYVRTAAFSPSSLLVSGSYDHTVKLWDTRMTMSTGMPVESTVPGG--ETLATSSGPIVRIWDIMAAFSNHQKAVTSLRLLTGGLDQMVKVYD--LETFRVTHSMRFPA-PVLSVADNINLVAGLSDGTLAMRRRGAYEYMQEARRLRLKEFDKFLKKFQYSEALDSVLTTFALLLELINRDGLKQAISGRDDIGLEPLVSMLVKWIVDPRVAVPVASAIIDIYGGVVGQSIDNLLTRLRKKVDDEIKVQNEFMNAKGALDMIFA Zygro1 TPEQRYWRQYSSAQ-LVKEHNIAFNPFAVTSSTRVQLFSSRTRQVIKTFSRF--KD-VVYSASFRNDGKLLCAGDATGLVSVYDSPRA-LLVSINASTHPTHVTKFSLVTASDDRITRVWDISYE-PQLELASDYVRSVNFVPAALVMTGSYDGHVRLYDTRYSLDHGVPVEDIVSP---TQVASCGGSNFKVWDLTSERGNFNKTVTCLTLLASSLDGHVKVFD-PLDNYRVKFGWKFSG-AVLSCAGTKHLVAGMSSGLLAIRTKNNYQRMMRGQTQRIRAFEKNINQFKWAEALDSAFLTLTVLQELRKRGKIRVALYGRDEASLEPLLNWCLKGIEDVRVVADWIAVVLEMYGSALENSLRELVLSLKDKVRQEVYNAKEAQKIEGMLQLLTN [Cluster1870.fasta_al_trimmed; alignment length = 184] Allma1 QVGIAGRHMGDRLQLQQLQDQMAQFKSSLELFATKHRAEIARNPAFRRQFAQMCAGMGVDP-L-SSKGVWSDLLGVGGFYYELGVRVMELCIALRERWGPLVPLADAVKALNHERVSEDDVTRAVKLLAPLGGGFALG-TVAVIAAVPRELNLDADRVARMDRAQRCLVADGIVWVD-TFWFSA Ashgo11 KFGVAAETLGIN-QNQELKEQLTIFQERLAEFAKDNNKELRANPELRVKVLKMCSKIGIDP-LDKDKHLFH----VDDYYYELCVKVIEICRRTKDLNGGIIAFEDLHRGYFK--VQVDDLEKAISMMKSLDGGFEV--GKKYLRSVPNELTGDQTKILEIVRSKAVLVAKGLLWID-EYWDPA Aspfu1 GVGLGAANHGANLHLESLQTQLSVFQSLLHTFALEHGSTIKSNPTFRAEFARMCNAIGVDP-LGESASFWTQIMGMNDFYFEVAVRVVELCRSTRSDNGGLLGVEECRKKVGKGKVTDDDVLRAVKSLGPLGSGFSIG-SKQYIRSIPKELNTDQATVLEAARAQTVIVADGLVWVD-TYWSPQ Aurde31 -AGIAGSTLSNKLQIDAMHTQVDHFRTALQRFAREHRADILRDPALRGAFVQMCASIGVDP-L---GKWWTELVGLSEWQNELGVQVCDVCIGTRDRNGGLIEMRELVRVLCRMRVSEDDVVRAIRSLKPLGAGYEVG-DTKFVRSVPRELDVDQTQLLALERARAGLVRDGMCWID-EYWVPS Batde5 RVGIHGQKAGEALQLEQMKNLLATFKTNLEEFATKHKKDIKRDPVFRMHFQRMCNNVGVNP-LASNKGFWSDILGFGDFYYELGVQIAEVCLATRERNGGLIDLGELMQLVTKMRISMDDIIRSIKALKPLGNGFDIG-SRSMVQSVPRELDGDSTKVLSLERISKVLLKDGICWID-TYWVSG Botbo1 GAGIAASELSSSLQVASLQSQLATFRASLSRFASSHRSDIRRDPEFRRAFQQMCAAIGVDP-L---GSWWAELLGLGDWQYELGVQVVGICVSTRERNGGIIEMRELLRLLTKLRITEDDVARSIKIMETLGAGYEIG-DKKMVRSVFKELDNDQAVVLEIERVRVALFRDGLCWVD-EYWVPA Botci1 GVGLAAASHGNTLHSTSLATQLSVFRSLLQQFAQTHAKDIRSNPTFRAEFARMCSAIGIDP-L----SFWAQMLGVNDFYFELAVRVVEVCGATREENGGLIGVKEVKDRIMSTRIT--------------------------------------------------------------Y---- Caeel RIGVAAAAKGDQMQLVQFSQQLEQLSAGLEMFAQRHRDEIKKNSQFRRHFQEMCASVGVDP-LASSKGFWAKALGFGDFYYELGIQIVEICLSTTHINGGIMTVEEIRNRLMRTRISTDDILRAVDKLKVLGNGFELGGGRFLVQSVPGELSMDHSRVLQLARASSALVKEGLAWTD-EYWFPS Canalb1 ------LQLGKSLHSNQLSTQLQVFQSALINFANDHGDEISSNLEFKNKFTQIVQSIGIDP-LSNSSSNYKR---ATNFGVALAVKIIEICQQTRDLNGGLISLKELISTLQN--VSEKDIESSLNNLNTLGKGYEIN-GKKWLKFSSTNLSNDQLKIYELVRCKTVIIMNGFLWVD-SYWEPS Cangl NFGLSAKNVSSNIQSLELEQQLEVFQGRLIDFAKKHNKDLKANPEFRSRFLRMCSSIGIDP-LEKDQHLFN----VDDFYYEISVKIIEVCRETKDMNGGVISFDELRNGYFK--VTMEDLEKSIDMIQVLDGGFKV--GKKFLRSVPNEITGDQTKILEVVRGRSVLAANSMLWID-NYWDPS Capow GVGLAGVSKGNELQLAQITQQLEVFKSNLEEFATKYAKQIRKNPTFRQQFQVMCGTIGVDP-LASTKGFWSELLGVGDFYYELSVQVVEVCLATRASNGGFITMQELMTRLTKRRISEDDIERAIKKLKTLGRGFDIG-KQRLVRSVPTELNADQTVVLAAERISAALLREGIVWVD-DYWPLS Catan2 NVGIAGKDMGDRLQLEQLKTQMATFKSSLEEFAAKYRKDIAKNPAFRLKFQQMCA-TSVSI-L-LQR-IWGDVLGLNDYYYDLSIRIMEVCLALRDAMGPLIPLHVLFTHLN--QLCEDDIHRAIGLLGPLGGGYELS-STPVVVTVPRELNPDFIIAAQRDRAHLCLVTEGIAWVD-QFWFSA Cioin GVGASAKEHGNELQLDQLSGQLETFHSHLEKFAANHKQEIRKNPQFRRQFQQMCATIGVDP-LASGKGFWSEMLGVGDFYYELGVQLVEICITTRPQNGGIIAITELHQKLMKTRVSIDDVRTALSKLKLLGTGFTLG-LKQIVKSVPGELNMDHSAILELERVQDVLTKEGMAWVD-TYWFPA CocheC53 TPGLSSTNHGATLNADSLSTQLSVFQSLLHNFAITHSKDIRANPAFRAEFARMCSALNIDF-LASGESIWTQLLGLNDFYFNLGVQIVEECRATRAENGGLISLSDLQARLSKSTVSDDDIKRAVDALAPLGSCFSIG-HRSLIRSVPKELNVDQSTVLEAPRAHAVIMADSLVWVD-TYWSPA Coere1 AVGIGGSKKGTELEIDKLQEQIGLMKTNLEEFVREHQRDIRNNPVFRVQVQRMCQLIGVDP-LASRKGYMAELLGVGDFYCELGIQIIDICVATRFMNGGLIDLEELRQRLIRRRVVEDDIKRAISQLAPLKGGYRIG-GRKIVQSVAREMNADTSMVLGLHRIRACVLRSGIIWVD-HYWVPA Conco1 RVGVAGSQKGNEIQLEELNKQFSQFQTNLEQFSKLYQKDLKKNPEFRDYFHKLCRKIGVDT-LASSNGFWSKLLGEGDYYYELGIQLIEICINSRELNGGLIQLSNLHKQLQVKRVTKEDIVKCLKTLNPLGGSYKLG-KEEFVQSIPRELNRDQTEAISLERTSQLLIAEGLFWLD-DYWLAT Conpu1 GVGLAAAELSSELQVDHLQIQLTQFRSALTHFATTHREHIKKDPAFRHAFQRMCVSIGVDP-L---GGWWAEMLGIGDWQYELGVQIVDVCVSTRERNGGIIEMSELVRMVSKLRITEDDVVRSIKTLEPLGAGYEVN-GRKMVRSVVKELDEDQAIVLAEERARAALLRDGLCWVD-EYWVPS Copci GAGLSAAALSSTLNLQNLQNQVSQFREALSRFAKLHRAKIREDPIFRYEFQKMCVSLGVDM-L--LSGGFGELLGVGDWQYELGVQIVDICVSTRERNGGLIEMEELIRILSKLRITENDVVQSINSLKPLGAGYQVG-GRKMVRSVMKELDEDQAVILAIERARTALLRDGLCWLD-DYWIPS Croqu1 AVGISSDTLSDSLTLTNLQSQLSTFQSALKAFALKHGHRIRSDPEFRTAFSSMCAELGVDP-LGGRKGFW-DWVGIGDWTFELAVQVVDVCLATRDRNGGLVEIGDLLTSVRGLRVSEADIGRAIKALEPLGSGYKIG-QQKFVRSVPAELDSDSVAVFDADRTSDAIMTDAMLWVD-QFYAPA CryneH991 GAGISGSTLSSNIQLSNLTSSLQSFRAALINFASAHRADIRKDPAFRHQFQKMCAAIGVDP-L-GGRGWWSEVLGIGEWEYELAVQVVDICVSTRPENGGMIEMGDLIRRVERLRITSQDILRTLKLLRPLNAGYTL----TYIRTIPRSLDTDQSTLLALVRVRTAMMREGLGWVD-EVWIIA Crypa2 GVGLAAASHGNTLNAQALETQLSVFRSLLQQFAQTHAKDIRSNPSFRAQFARMCAAIGVDP-L----SIWAQLLGVNDFYFELAVRVVEVCGETRSENGGLIEVRKVRERIMRGRVTEDDILRAVGTLKPLGSSFSVG-SKPYIRSVPKELNTDQSAVLEAARAQTALLGEGMLWID-KYWSPG Debha1 ------SQLGQNLHSDQLSTQLSVFQSALINFGSDHGDEIRRNPEFRNKFTQMCQLIGVDP-LSRNEDFY----------IGLSVRIVEVCQETRDVNGGLISMKELLSRLQ---IRESEIQQALSILFALGNGYEIN-GKKWLKFSSANISNDQKKIYEVIRCKTVIIMDGFLWID-SYWEPS Dekbr2 GRGLASQTLGRKLQREQIKTQLQVFQNALITFRKQHAEELRSNPDLWSKFSEICRSFGIDP-L----------LGRQEKYNQLALRIIDICRLTKSLNGGMLLVDDLLDLINCESITEQDVLTSLDNLKALGDELQLG-NKNYIKSTTEEINADQGLILSAYRCKSNLVSNGILWVD-DYWITS Dicdi GIGIQAQNVSEQLNINKIKEQLLVFKENLEIFATKHKKDIIKNPEFRKYFQDMCNMIGVDP-LASNKGFWCQVLGVGDFYYTLGVQIIEICLKYRSSNGGLMEMDTLAEHLRKLRISCDDIECSISKLKVLGNGFNISGGKKLVQSVPCELNKDHTDIIILERINNVILQESMIWID-EYWFPS Dmel RVGLGAKDKGTDLQLEQMTKQMEVFRVKLEEFAMKHKEDIRKNSQFRKQFQEMCAAIGVDP-LATGKGFWS-VLGMGDFYYELGVQVVEVCLAANHKTGGLMELDDLRRRLIAARITKEDILMAAKKLSIFGNGFVVGKGKYIVQSIPGELSMEETNILNAYRAQQSLLGEGLCWID-KYWFPS Enthi ------STKGKEFNQKERERQINLFKLKLEEFLQNNRYEITNDVNIQNMLYILCRKMGVEP-LTTEKSYFNIFFGSNAFYNELTVQIIEECYKSRESNGGIIEINKLCELINKKRIRQNDIFKAINQAKCLGEGLKV--QQSYVISVPFELADDQQVVLTLERVKGTLLNIGMLWVD-DYWTSL Falba --GIGAKKLGESISIKELDEQLQQFKTHLEDFARRHHRALKTDPHFRSRFQEMCSAIGIDP-ISSSRGFWTDLLGMGDFYYNLGVEVVAACNNLQSTTGGLVAIDELVSLLLPRYICADDIERAIKSLKCLGAEYSIG-SKKMVQSVPRELDTDLLVFLGRERVLRAALQMGLVWID--YFLPR Fomme1 GVGLAAATLSDTIQVDSLRSQLAQFRSALQHFASTHRDKIKRDPAFRHAFSQMCANIGVDP-L--GGGWWSEILGLSDWNLELGVQIVDICVSTRERNGGLIEMAELVRLLGKLRITEEDVVRSIKTLKPLGAGYEVG-GTRMVRSVTKELDIDQGVVLSVNRAHAALVRDGLCWLD-EYWIVS Fusgr1 GVGLAAASHGSSLNAQALETQLAVFRSLLQQFANTHARDIRSDPAFRAQFARMCAAIGVDP-L--GSSIWAQLLGVNDFYFELAVRIVEVCGATRGENGGLIGLADLRERVAAGRIADDDVRRAVQTLGPLGGAYAVG-RKEYVRSVPRELNDDQVSVVEAARARTVIVAGGMLWVD-KYWSPG Galma1 GVGLAAAELSSELQVENLHSQLDQFRTALAHFASTHRESIKNDPSFRHAFQQMCSSIGVDP-L---GGWWAELLNLGDWQYELGVQIVDVCVSTRERNGGLIEMFELVRLVSKLRITEEDVVRSIKTLQPLGAGYQVD-GCKMVRSVVKALDEDQTVILAADRARAALLRDGMCWLD-AYWVPS Ganpr1 FAGIGDRELGKKLELEKMKQMLQDLQVNLRKFAEQHRDEILSNSEFRTKFQKMCDEIGIDP-LASRKSAWSS-LGVGDFYFQLAVQCVDVCVATRAQNGGLMDLEELQRRVNRLRVSFDDLERAIKSLAPLGGGFQVG-NRRLVQSVPAELSSDSGAVVGTARAQAATVRSGTVWVD-DFYVVA Gloin1 --------------MEQMKSQLQVFKSNLVEFSRKYRKSIRKDPVFRQHFQTMCSTIGVDP-LASNKGFWSELLGVGDFYYELGIQIIGVCLSTRGRNGGLVELGELKRQLTKMRISDDDIIRSIKTLKPLGNGFEIG-DRKMVRSVPRELNKDQTDILVLERINDAILVDGLCWID-EYWVPS Hisca1 GVGLGAATHGANLHLTSLQNQLSVFQSLLHSFALEHASTIKSNPTFRAEFARMCHAIGVDP-LGEGGSFWTQILGVTDFYFEVAVRVVELCRETRGENGGLIGVEECRARVGRGKVSEDDILRAVKSLEPLGSGFAIG-SKQFIRSIPKELNTDQATVLEVARSQTVILADSLVWVD-TYWSPQ Klula1 KFGVAA-DLASNKQNNELNEQLSIFQVKLVEFARQHNKELRDVPRFRAKFMRMCSAIGIDP-LDKNSHLFH----IDDFYYQICVKIIEICRNTKDVNGGVISLEELHVNYFK--IEMEDIEKAIIMLGPLDGGFEL--QKKFLRSVPNELTDDQTKILEIVRSQSVLVASGLIWVD-SYWDPS Lacbi2 GVGLAAAELSSALQVDHLHLQLNQFRTALVHFATTHRKSIKNDPSFRYAFQQMCSSIGVDP-L---GGWWAELLGLGDWQHELGVQIIDVCVSTRERNGGLIEMSELIRLVSKLRITEDDIVRSVKTLQPLGAGYQIG-GTKMVRSVMKQLDEDQTVVLSIDRARAALLRDGLCWLD-EYWIPS Lenti61 GVGIAAAELSTEIQLDLLHAQLAQFRSALAHYASTHRDRIRQEPSFRHAFQQMCTTIGVDP-L---GGWWAEMLNLGDWQYELGVQIVDVCVSTRERNGGLIEVGELIRLVSKLRITEDDVMRSIKTLKPLSAGYEVG-GKKMVRSVPRELDADQAVVLAVERARTALLRDGLCWLD-DYWVPS Malgl1 ----------------------------------------------------MCASLLVDP-LGQVVNLWSELTGFSDWQYELGVQIVDVCISTRSQNGGIITMDALIRGVLHLRISSSDIERSIKALEPLGCGYEV--GIKMVRTVARELSTDSKHVLNFDRAAKTLMDDGTLWLD--YYAIA Mellp23 AVGISSSTLSESLTLTNLQAQLSTFQAALKAFALKHGHRIRSEPEFRATFSRMCAELGVDP-LGGRKGLW-DWVGIGDWTFELAVQVVDICLATRDRNGGLVGMEDLIHSLRSLRVSESDVARAIKALEPLGSGYKIG-EKKFVRSVPVELDSDSLEVFDSDRTRNAIMTDAMLWVD-EFYAPA Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr HKKFACSRAGAQLELAQMESQMTLFKERLEDFASKHLDKIRTNPEFRAQFQQMCLRIGVDP-LASQKGFWQKTLGLGDFYYKLSVQVIEVCYATRAVNGGLIDMEDLLSRVRKRRVSRDDIVQAVEKLRVLGSGYTLG-SRTIVQSVPLELSQDHSIVLLL-------VQQGFAWVD-EYWFPG Morel2 ----MNQRVGQSIQLEQLQSQLDTFRSNLENFARNHRKDIQKDPVFRMHFQKMCGNIGVDP-LASSKGVWGELLGVGDFYYELGIQIIDVCLSTRALNGGLMELSEVKRRVERMRVTEDDVLRSIKTLAPLGSGFQVG-EKKMVSSVPRELNRDQSIVLGLGRAKTALLNDSLMWID-QYWVPG Mucci2 ---------------------MDVFKTNLQEFAQKHRKDIRKDPTFRAHFQRMCTNIGVDP-LASNKGFWADLLGVGDFYYELGIQIIEACIVSRINDGGLTELSEIMRRVQVMRISEDDIVRAIKTLKPLSGGYEVG-DRKLVRSVPKELDKDQSALLLLERIKTATLQDGIAWLD-KFWIPS Mydma GPGLASAAKGTELEISYMIKQLDAFKHYLEDFAAKHQSDIKKNPEFRQHFQTLCAKIGVDP-LASSRGFWSEILGVGDFYYELSVQITEVCLATKNKNGGLIAINDLLRLVLKGRISEDDLIRAIKKLGVLGSGFKVP-GRTLVQSVPTELSVDHTTVLQTNRVQNILIQEGMAWID-TYWVPG Neucr2 AVGLAAATHGSALQASALETQLSVFRSLLQQFAATHAKDIKSNPTFRAQFARMCAAIGVDPLL-KGDSMWAQLLGVNDFYFELAVRVVEVCGETRGENGGLIEVGMVRERVVKGRVTEDDILRAVGTLKPLGSAYSVG-SKQYIRSVPKELNTDQSAVLEAARAQTALVGEGMLWVD-KYWSPG Orpsp11 ------QKIGDELQLEQMQAQMVQFKEQLEIFAKKYKNDIKKDETFRQNFQSMCTSIGVDP-LASSKGFWGEILGVGDFYYELAVQIIQVCYLSRSKNGGLIEINELKKTLTEIRISV------------------------------------------------------------------ Pench1 GVGLGAATHGANLHTASLQTQLSVFQSLLHTFALEHSSTIKSNPTFRAEFARMCNTIGVDP-LGEGGSFWTQIMGMNDFYFEVAVRVVELCRETRSENGGLIGVEECRKRVGKGKVSDDDILRAVRSLEPLGSGFSIG-SKQYIRSIPKELNTDQATVLEVARAQTVILADGLVWLD-AYWSPQ Phybl2 PVGLANQQVGDSIELEQLQSQIEVFKSNLEEFAWKHRKDIRKDPTFRSHFQRMCATIGVDP-LASNKGFWADLLGVGDFYYELGIQIIEGCMATRTRDGGLTELGDLKRRLDNARITMDDIVRAIKTLKPLSGGFEVG-ERKMVRSMPKELDKDQSALLLLARTQTGLLQDGLAWID-DYWIPS Picst3 ------TKLGRSLHSDQLSTQLAVFQSALINFALDHGDEIKLNSEFRNKFTHICQLVGIDP-LSSQDSNYT---------ISLAVRIVEVCQETRDVNGGLIRLKELVSIIR---VTEANIEKSLATLTTLGKGYEIS-GKKWLKFTSASITNDQKKIYEIVRCKSVIIMNGFLWVD-SYWEPS Plicr1 GAGLAASELSATLQLSNLHSQLTHFRTALAAFAATHRDSIREDPAFRHAFQQMCASIGVDP-L---GGWWAEMLNLGDWQYELGVQIVDVCVSTRERNGGLIEMHELIRLVSKLRITEHDIVRSIKTLQPLGAGYEVD-DRKMVRSVVKELDEDQAVILAVDRARAALMRDGLCWLD-EYWVPS Polpo GVGIQAQNISEQLNLKKISEQLTTFKTNLEEFALKHKKDIIKNPEFRKYFQDMCSTIGVDP-LASNKGFWCQVLGVGDFYYQLAVQIIEICLKYRSTNGGLIELTTLTDHIRKMRISSDDVEVSISKIKVLGNGYNID-SKKIVQSVPCELNKDHTDVLIKQRIKSVLLSEGMAWID-DYWFPS Pucgr2 GVGISSSTLSDSLNLAHLQSQLLLFQTSLKTFALKHGSKIKSDPEFRGAFSAMCNELGVDP-LGGRRGIW-DWVGFGDWTFALAVQVVDVCLSTRDRNGGLHEMQDVLKAVRSLRITEPDIARAIKSLEPLGSGYSIG-SKKFIRSVPAELDNDSLVIFDSERVKDALMRDSMLWVD-AYYAPV Punst1 GVGLAAVELSNELQLQNLHSQLAQFRAALLRFASTHRDSIKRDPAFRHAFQKMCSSIGVDP-L---GGWWAEMLNLGDWQYELGVQIVDICVVTRERNGGLIEMSELVRLLGKLRVTEEDVVRSIKTLQPLGAGYEIG-GRKMVRSVVKELDADQAVVLAVDRARAALLRDGLCWID-EYWVPS Rhior3 ---------------------METFKANLQEFAQKH----------------------------PNKGFWADLLGVGDFYYELGIQIIEACITSRSSDGGLTELAEIMRRIKTMRITEDDMIRAIKTLKPLSGGYQVG-DKKLVRSIPKELDKDQTTLLLLERIVAAT---------------- Rhoto1 AAGLSSTTLGTSLQASTLSSQLSTFQSALSRFSSHHRAKILSNPEFRTHFSALCAELGVDP-LGGSKGLW-DKMGLTDWYYALGVQVVDVCLRARERGGGLVALDEVIREVQKLRITEADVQRAIEALEPLGCGYTIG-SKKVVRCSPGQLDRDSLVAVEAERVERALMDDGMLWVD-EYYAPG Rozal11 GVGIAGREKGDEISLQQVERQLQTFKANLEEFAKKHNHEIKKDPVFRAQFHKMCSALGVDP-LSSSKGFWSELLGFGDFYYEIAIQLIELCIKERGKTGGLLDLEEVLKQFAKIRISEDDIQRALNTLKPLGCAYSIG-KRKMIKCIPKELNQDTLLILIHNRVDLAVLSQGMIWID-DYWIPS Sacce1 QFGLAANDVNKTIQSVELRDQLMVFQERLVEFAKKHNSELQASPEFRSKFMHMCSSIGIDP-LDRDKHLFT----VNDFYYEVCLKVIEICRQTKDMNGGVISFQELEKVHFR--VGLDDLEKSIDMLKSLE-CFEI--GKKFLRSVPNELTSDQTKILEIVRSKSALVANGLLWID-YYWDPS Salro VKGVRGQALGEKSQAQEMHKQLGIFKENLEEFARKYKKEIKRSPDFRGDFQRMCHQIGVDP-LASNKGFWSQLLGVGDFYYELGVQVVEACMATRGLNGGVIDIAELLNAVNTRRVATGDVEEAVARLQVLGSGFRVD-NRRVVVSQPKELNADHMAIFNRDRAQTALVQRGVAWVD-EYWVPG Schco3 GVGIAAAELSSTVQVADLKSQLEQFRTALARFATQHRDTIKNDPNFRHAFQQMCATVGIDP-L---GGWWAELLGLGDWQYELGVQIVDVCVSTRTRNGGMIDMSELVRHVTRLRVTEDDIVSSIKTLEPLGAGYQVG-GRKMVRSVPKELDQDQAIILDLERARAALLRDGLCWLD-DYWIMS Schpo1 RIGIGAEEVGNELQSDEIASQLSTFQEALKTFAREHATEIKQNSQFRNTFVKLALKIGLDP-FGSDESAWAAV-GMNEFYYQVAVRVIEVCYATQMENGGLLSVSQVCRFLNEENLRETDVVRAVDSLAPLGPGFVLA-GKQYIRSLPLELNTDQNVVLEASRCIQVLVSKSLLWID-SYWGAS Sorma AVGLAAATHGSALQASALETQLSVFRSLLQQFAATHAKDIKSNPTFRAQFARMCAAIGVDPLLNKGDSMWAQLLGLNDFYFELAVRVVEVCGETRGENGGLIEVGMVRERVVRGRVTEDDILRAVGTLKPLGSAYSVG-SKQYIRSVPKELNTDQSAVLEAARAQTALVGEGMLWVD-KYWSPG Sphar GPGIAGKQVGAEMEVASMTKQMEVFKSQLEIFATKHKKDIRKNPQFRAQFQQMCVQVGVDP-LNSKKGFWSELLGVGDFYFELGVQIVEVCLASQKRNGGLMEMDDVMKSLKKVRVSQDDCERAVKTLKNLGKGFDFG-NDSLIQSIPAELNKDHQAVFKLLQATKCLLKETLVWQD-DYWFPF Spipu1 RVGIHGQRAGEALQLEQLKTQLSVFKTNLEDFARKYRKDIKRDPKFRMHFQRMCTNIGIDP-LASNKGFWSELLGVGDFYYELGVQIAEICIATRERNGGLIDITDLKRLLERLRISEDDIVRSIKNLKPLGNGFDVG-SRKLVQSVPRELNVDFSTVLNLDRSQRVLLKDGICWID-MYWVAG Sporo1 TAGYSSSTLSDSLQSATLASQLSTFQSALSTFSTHHRAKILSSPEFRTHFSHLCAELGVDP-LGGGKGLW-DKIGVTDWYYALGVQIVDVCLQKRDRGGGLVALDEVMRDVRRLRISESDVQRAIEALDPLGCGYSVG-GKKVVRCSPGGLDKDSLVVIEADRVEHAIMDDGMIWID-EYWSPA Stehi1 TPGLAHQTLSNDLSLSTLHSQLATFRTHLQTFATTHRSKIRQDPNFRHAFQQMCASIGVDP-LMGLGGLW-EGLGLGEWMIELGVQVVDVCVSTRERNGGLITMEELIRIISRLRITEDDISAAIRTLEPLNAGYTIT-SHKLIRSVPSPLDSSILPILSLERARTALLRDGTCWLD-EYWVPA Tapde11 RGGLAAKTFGTDLQYEQLSSQLETFQQALSAFAATHAKDIRANPAFRTQFGQMCAAIGIDP-L----SFWNAMAGLQELYHNLAIQVVEICRRSRSQNGGLMRVSDICEKINTHNVSEDDVVRAVESLKVLESGFKVG-SNQMVRSVPQELNQDQSVVLEAARSQQVFLGNGMLWID-TYWLPS Thetr RGGIGGEDVGASVKVQNVREQLEVFQSSLASFAAQYKSDINRNPAFRMHFQRMCADIGVDT-L-----------------------------QSESRSG----------------FTTSSASRSSTSASPPSSSWTSK-SLRTTSSAPSSLATATPSSTSVGRSRRTGLRSGT--IDATRWMRS Treme1 GAGISASNLSTSLQLNSLQSSLSQFRESLLLFAQKHKSDIRSDPVFRYKFQQMCSAIGIDP-L-SSMGFWSR-LGLGEFAYELAVQIVDVCISTRGLNGGMIEMNDLIKRIEKMRITSQDIKQSLKLLQPLKAGYSLG-EQTWIRSIPKQLDMDLSLLLGIIRVKRALLDSGMGWLD--VWVLA Trire2 GVGIAAASHGSSLNAQALETQLAVFRSLLQQFAATHAKDIRSDPSFRAQFARMCSAIGVDP-LGGGNSVWAQLLGVNDFYFELAVRIVEVCGATRAENGGLIALADLRERVSRGRISDDDVRRAVETLKPL-GSYAVG-RKEYVRSVPRELSTDQAAVVEAARCRTALVAGGMLWVD-GYWNPG Umbra1 AVGIANQEIGDNIEIQQLHDQLDTFKTNLQEFARKYRKDIRRDPTFRMHFQQMCTKIGVDP-LASNKGFWADLLGFGDFYFELSVQITEICIATRPQNGGLIEMGELKRRIKVKRISEDDIVRSIKTLKPLSSGFEIG-NRKMVRSVPKELDTDQSSLLLLGRILQALLQDGLAWLDLSYWIPS Ustma22 GPGIAASSLGADLQLAELRQQLELFSTSLRHFSSQHRHEIRKNAQFRHAFQKMCYSIGVDP-L-GLAGLWSDMLGLGDWQYELGVQIIDVCVSTRDVNGGVISMDDLITRVTRLRITQDDIVRSIKMLAPLGCGYEVG-GQKMVRSVPRELDTDTMVVLGMDRARAVLLREGMLWID-EYYSLA Walse1 NKGIGSQNLSNTIQLQAVKQQLDVFKDYLKEFSIKHRKDIESNVEFRNRFTQMCATIGVDP-LIARGSLFSNLTGISDFYLSLAVQLVDMCISTTTLTGGLVRLSDILKALSIKRITLSDIQKAIKILQPLQHLYEIN-QILYLRSQPKELNNDQMLLLTSDRARNSLMDDGIVWIDNQYYFPA Zygro1 RFGLAAEGISSAVQNNELKEQLAVFQERLVGFAKKHNSEIQANPEFRSKFVRMCLSIGIDP-LDKDKHLFN----VNDFYYEICVKVIEICRKTKDMNGGVLSFDELEKGYFR--VDMGDLEKSIDMLQSLDGGFEI--GKKFLRSVPNELTGDQTKILEIFRSRAVLVANGLLWID-EYWDPS [Cluster1872.fasta_al_trimmed; alignment length = 162] Allma1 QATANLADAKLAQLGHVLARDLLECGCLVSIRAAFERYYAQVAPFYIRGLHLLHLLAQHR--IAEFHAALELVNPYIAHAVQLEQALMDGSLHHVWDALVLTLRKEMANAIEVAYAPSLPVAALARRLFLDQLRALCNEQ-GWQMGVIQHALMYARELERIV Ashgo11 TCVDLLGPIKLIKTRLEVAKKILEIGALSSINAGFENYYAQLRAFYLISLYLLILLSQGD--VTKFHSELEFLNKYLSYPVRLEKLLMEGSYQKAWETLMNAIRDSIARNTEVAY-ARLPLSNVKALLFFKDTEAFAKAR-GWNISIVSKALSYATNLESIV Aspfu1 AANNLLSQAKLLLQNIALAREVLELGALASIRQGFTRYYQQLQPFYITGLYLMLLLSMGD--STSFHTVLEGLDLYIKYPVDLERSLMEGSYDKVWNVLVGTIRSEIADCSEKAY-PSLPISNAKNLLFLGAVIEFAQQR-GWVLTVIENTIGYARELETIV Aurde31 KCGSLLGKLKVIENGLVVARDILEIGAFWSIRPSFDRYFAQLQTFYLRGLNLIRLLTQNR--IADFHTILESLNPFIKHPVNLERWLMEGSYSKVWDSLIGTIRNEIASCEEAAY-DSIPLKDAATLLFFSDLIQFAQKR-GWQIKLILSNLSYARELEQIV Batde5 KAGQSLAKLKLTGMSILLAREVLEIGALWSVRPSFERYFAQLKSYYLIGLNLLRLLAQNR--IAEFHTELETINVYIKHSVQIEQCLMEGSYNKVWNILMGTIRNEIASCSEKTY-NTLPIADATTLLYFEQFFTFAKER-GWNVNIIQQTLGYAHELEQIV Botbo1 LCGTLLSKLKLIEAGLAVTREILEIGAFWSIRPSFDRYFSQLQTFYLQGLNLIRLLTQNR--IADFHTTLEALNAFIKHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCGEAAY-ESLPVHDAAALLFFNDLITFATQR-GWQVEMIAASLGYAKELEQIV Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel AVEKALNELTVLSASALASKDLYEISVLLAILETFDDYINQMHTYYMTGLHLMFLLAANR--LSDFHMLLEQINAYISTPVRIEQSLMEGAYNKVVRIMLDTIRREIATSIEKSF-KVLTAKDATVMLLFEQMKKFGQER-KWHLRVATQTLFYAKQLEQIV Canalb1 GCQQLLAPIKLVKHDLRIAQRILEIGALSSLLSGFENYFAQLRPFYIISLYLLYLLSQGL--ISKFHVELEVIDKYLQFPINLESNLMEGNYIKIWDTLINALRFEIAKSLEKTY-DSIPISNCKNLLYLLSDANFEKTD-NWKF-VIKNLLGYAEQIESIV Cangl TCKKLLPAVKLIKNNILFTRKIFEIGALVSIYEQFYSYFAQLRTFYIISLYLLTLLSEGD--VTKFHSELEYFDQLLSYPIKVDRWLMEGSYQKAWKTLMNAIRDEIARNTELAY-KNLPLTSIKALLFIKETELFAKER-GWKIDIVDKALDYAINIESIV Capow LCGDLLIQLKLTELSLLLAREVLEIGALHSIAAAFDRYAVQLRTYYLLGLHLLRLLSQQQ--IGDFHVALERLDPFVRFPIALEQHIMEGLDHQVFEQLLQTLRSN----AESDK-LKLSVGDARKL---IELHDYSAQ-------VIQNALGYAKELERIV Catan2 NCATLLAKAKLAQSRMILARDILEIGALHAIHPSFERYYAQLSTYYLNGLYLLSLLAQNR--IAEFHASLELINPYIRHAVLLEQALMEGAYNRVWDLLMGTIRNEIAACAERSF-DHLKLSDVGVLLMFQQVREFCASR-GWTVLVMKDVLGYAKELERIV Cioin VCAQHLCKLKLTGLSFVLARDVLEIGAQMSIMPAFERYMSQLKCYYLLGLNLLCLLAQNR--VAEFHTELERLNVYIRHPIAIEQYLMEGNYNKLFDILLGTIRDEIATCIEKSY-PRISYTEARRMLYFNELDQYSKNR-DWELELAQQVIKYAKELEMII CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 AIKSQLSQLKLVGLAQVLKRSVAELGAELSIKAAFERYMAQLEPFYLIGLNLLRMLSDNL--IADFHTVLERINPFIVHPVKLEQALMEGSYKKVWDILMSTIRNEVASCVEKSY-VSLPFDDAKSVLFFDELLRFAQEH-QWSVNIMKQTLSYARELERIV Conco1 VCHKTLGEAKLIKLGLLVARNILELGALLSVRHSFERYITQLEVFYLTGLNLMRLIAQNR--ISDFHMALEKVNIFIKYPVEIEQSLMEGSYTKVLDILIITIRNEIASCCEKAY-ESLPLVDVGAILFLSELMNFCKER-RWQIKIITQTLGYAKELEKIV Conpu1 KCGTLLSQLKLIEAGLAVARDILEIGAFWSIRPSFDRYFSQLWTFYVRGLNLIRLLTQNR--IADFHTTLESLNPYIRHPVNLERWLMEGSYSKVWDSLMGTIRNEIARCEEAAY-ETLPLKDAATLLFFSELLRFAEQR-GWEIKLIVANLLYARELEQIV Copci ACASLLAQLKLIEAGLVVARDILEIGALTSIRPSFDRYFSQLQSFYIRGLNLIRLLTQNR--IADFHTTLESLNPYIKHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-ESLPIKDAATLLFFSDLAKFAAER-NWQIKLIAASLLYARELEQIV Croqu1 QIGQLLLKLKLAESSLRKARDVLEFGAFYSVRPAFERYISQLAPYYIIGLDLLRLLSQNK--IAQFHTVLEGLNPYISHPVNLERWLMEGSYSKVWGLLVDTIRNEIASCEEKAY-ACLPLSDAGTLLFFGEVIEFAQQR-NWQVKVIEATLGYAKELETIV CryneH991 QVSTQLAKLKLAQSGLVAARSILEIGAFQSLRKSYARYNFALQPFYTLGLHLLGLLSENL--LTEFHTLLETLDSFVRLPVDLERWLMEGSYNKVYERLMGTVRGQIASTIESSY-PSLPLQHAATLLFFSSLTDFASAR-GWSLTMVGPALRLAQQLEAIV Crypa2 DAASLLSKAKLLKLSLALARETYEQGALYSIRDAFTRYVTQLAPFYVTGLYLLLLLTQGR--YAEFHSELESLDRFLGYPIRLERWLMEGSYDRVWEILTSQIRSEIASSSERAY-PSLPISSTKSLLFLGAVIDFAKSR-GWILLVIENALGYARELETIV Debha1 QCQKILTPIKLIKHNLKIAERILEIGSLASLLQGFENYFAQLKPFYIISLYLLYLLSQGL--ISKFHVELEYIDSYLQFPINLERNLMEGNYNKIWDTLITALRFEIAKSLERTY-ESLPVSNCKNLLYFQSDSVFQQFE-TWSFAVINNVLNYAEQIESIV Dekbr2 TCVKSLTPIRLVKNGMVITRSILEIGALASINSEFSNYITLLKPFYLLSLYLLLLLTQDG--LASFHVELEKFDEFLQVPIKFEKWIIDGDFNKVYSDLLSSIQLNIAESLQSAY-KNLPLENLKMLLFLEEANSFITEF-GWTLLIIKNALGYAREMESII Dicdi QITPVLVQLKTIHLELVLAREILELISLYSIKDSFERTFNQLKTYYIIGLNLMRLLAKHK--TSEFHSEIELINSFIKFPLLVEKSITEGSYNKIIDILADSIKEDIANCSEKSF-KTLSLKDAEKVLLFNQFQQYIKER-NWKVQLIHQTLHYAKELERIV Dmel KCGQLLDQLKLVKMALILARSVLEVAVEHSVLLAFERYMAQLKCYYLLGLNLLYLLSGNR--VSDFHTELELLNQFIRPILALEQYIMEGRYNKIFDLLLETVRDEIGACIEKSY-DKISAKDAAKRLNLDEIKAFGAKR-QWKLELAEQVLSYARDLEMIV Enthi --------ME--------------------------------QKYY-IALQLLTLLAQNS--LAEFHIQIESLNNNIKQVISMEQFFIEGRYNRVLPLLKQTLVEAVAATIETAY-HILPIDYTKKVLMISEFNEVVANH-QWKIENISDSLSLIKEMDEMM Falba AAVAPLTELR-----LIMARDVWEMAALLAARATFERLFFQVSTLYLLALHLLFLLTENR--MADFHAALARLGPEVGYVAQLERWLSGGAYNKVLTVLSNTVRAEIATGIETAY-APLKIDAAGRLLQLADLDQFASQR-GWRVDLLFATLAYAQELDQIV Fomme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fusgr1 DANALLSKAKLLKLNLPLARETYEQGALFAIREAFTRYVQQLQPFYVTGLSLLLLLTQGR--YAEFHTELESLDRYLGYPIRLERWLMEGSYDRVWEILKNQIRSEIASSSERAY-PSLPISSTKSLLFLGDVISFAHHR-GWIVMVIENALGYARELETIV Galma1 KCQALLPKLKLIEAGLVVARDILEVGAFVSIRPSFDRYFAQLQTFYIRGLNLIRLLTQNR--IADFHTTLESLNPFIRHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-ESLPLKDAATLLFFSELLTFAQKR-GWQVRLIAASLAYARELEQIV Ganpr1 KCGQILGKLKLTELSLLLAREVLEVGAQYSIRPQFERYISQLKTYYLLGLNLLRLLAQNR--LAEFHAELETLNVYIRHSVQVEQCLMEGSYNKVWDILMDTIRNEIASCSEKAY-ISLPLADAATLLHFEEVLSFAKER-GWDVQVLTMMIGYAKELERIV Gloin1 KCGDYLAKLKLSKMQLLIARDILEIGAYWSVRPSFERYIAQLNTYYLTGLNLLRLLSQNR--IAEFHTALENISVYIKHPVHLEQYLMEGSYNKVWDILMGTIRSEIASCSEKAY-SYLPLADAATLLFFNELLNFASER-GWSVSIIKQALHYARELEQIV Hisca1 QAEKLVQKTALHKLGFCLAREALELSTITSLRVLFTTGYKLLKPFYITALYLVYLLSEGN--ITEFDTVLAGL-----------KMIPETPDEKQKPVLLSTIRMWMAASAEKAY-ESLSISSAKDVLKLGDVVEFAQAR-GWVLAIIENGIGYAQQLGTIV Klula1 TCLRLLLPIKLIKAKLNIAKKILEIGALSSIYETFMNYYSQLSAFYLISLYLLILLAQND--YTKLHSEFEFLSSYLSYPVKLERLLMEGSYQKAWKTLKEAIREEIALNSEQAY-SSLPLFNAKTLLFFKEMEAFAKER-DWSVDTVDMAIDYAVHLESIV Lacbi2 KCAAVLTQLKLIQAGLVVARDILEIGAFSSIRPSFDRYFSQLQTFYIRGLNLVRLLTQNR--IADFHTTLENLNPFIRHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-ESLPLKDAATLLFFSDLLKYAQNR-GWEVRLIAASLAYARELEQIV Lenti61 QTGVLLARLKLTEAGLVVARDILEVGAFWSIRPSFDRYFSQLLTFYLRGLNLIRLLTQNR--IADFHTTLESLNPYIAHPINLEQWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-DSLPLKDAATLLFFNDVLAFAKQR-GWQVRLIAANLQYARELEQIV Malgl1 AVGTQLALLKLTERDLLLARDVLEIGALWSIRTSFDRYWSQLVSFYIIGLSLLRDLSTNS--IASFHIALESLSPYIQHPVLLERWLMEGSYSNVWNSLMVTIRHEIASCEEKAY-DTLPLNDVATLLFFPEVLEFAKER-GWHVSTITTNLHFAKELESIV Mellp23 QIHQLLTKLKLAQSSLTKARDILEFGAFYSVRPAFERYIAQLGPYYIIGLDLLRLLSQNK--IAHFHTVLEGLNPYISHPVNLERWLMEGSYSKVWDLLVDTIRNEIASCEEKAY-ASLPLSDAGTLLFFGEVIEFAQKR-NWQIKVIEATLGYAKELETIV Mnele KCGGYLSTLKLTQLSLILARDILELGAQWSILPSFERYMAQLKCYYLLGLNLLCLLSQNR--VAEFHTELELLNIYIKHPIALEQYLMEGSYNKVFDILLDTIREQIASCMSSSY-TTVTVAEATKLLFYSKTKQFAEKH-GWQ-TVTQHLLEYAKELEMIV Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 KCGQFLSQLKLIELSLTLARDVLEIGAQWSVRPSFERYMAQLQTYYLIGLNLLCLLSQNR--ISDFHTALETINPAIQHPIKLEQSLMEGSYNRVWDILMDTIRNEIASCSEKAY-TSLPLSDAGTLLFFEDILNFAKER-NWKVQIIKQTMFYARDMDRIV Mucci2 KVGQLLTQAKLIELGLVTARDILEAGAYYSVRASFERYIAQLNTYYLIGLNLLRLLSQNR--LSDFHTALETINQFIKQAVDLEQFLMEGSYNKVWDILISTIRHEIASCSEKAY-EYLPLNDASTLLFLEELLNFANER-GWKVQIITRTLGYARELERIV Mydma KVGKLLTSMKLTELQLILARDVLEIGVHWSIAPSFERYMSQLKCYYLLGLNLMRFLAQNR--LAEFHTELELLNVYLKCPVQLEQYLMEGNYNKVFNILLDTLRDEVAACIEKSY-SHISTKEACRMLFFVDLTNYAATR-KWE-KLIEQFLGYAKELERIV Neucr2 DSSALLSKAKLLQLNFSLARQVYEQGALASIRDAFLRYVSQLQGFYVTGLYLLLLLTQGQ--YAEFHSELEALDRYLGYPIKLERWLMEGSYDRVWEILTFQIRSEIASSSERAY-PSLPISSTKSLLFLGEVVEFARSR-GWVLLIIENTLGYARELETIV Orpsp11 ----------------------------------------------IIGLNLLRLLAQNR--LSEFHTELETINVYIKHPVEIEQCLMEGSYNRVWDILVDTI----------------------------------------------------------- Pench1 AANDLLSRAKLLMQNVVLARQVLELGALASIRQLFTRYYQQLQPFYITGLYLLLLLSMGD--SANFHTVLEGLDACIKYPVELERNLMEGSYDKVWNVLIGTIRNEIAGCSEKAY-PSLPISNAKNLLFLGAVIEFAKQR-GWILTVIENALGYARELETIV Phybl2 KCNQLLAQSKMAELGLLVARDILETGVYYSVRASFERYIAQLNTYYLIGLNLLRLLSQNR--LSEFHTSLEAISTFIKQAVDLEQFLMEGSYNKVWDILINTIRNEIAGCSEKAY-EFLPLQDAGTLLFLEEILNFANQR-GWKVQIITQTLAYARELERIV Picst3 QCQNILPPIKLIKHNLKIAQRILEIGALLSLLQSFENFVAQLKPFYIKSLYLLYLLSQGL--ISKFHTELEVIDKYLQFPINLERNLMEGNYNKIWDTLIQALRFEIAKSIEKTY-ESIPINNCKNLLYFQSDAVFEKEE-NWKF-VIHNVLNYAEQIDSII Plicr1 KCGTLLAQLKLIEAGLFVARDILEIGAYWSIRPSFDRYFSQLQTFYIRGLNLIRLLTQNR--IADFHTTLESLNPYISHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEETAY-ESLPLKDAATLLFFSELLTFAQQR-GWEVKLIAANLSYARELEQIV Polpo KAKELLNHLKLIHLSCLLARDILEIAALYSVKSAFERFYAQLTTFYIIGLHLMKCLATQN--APKFHSELELINPFIKFPLLVEKSIAEGSYQKVLDLLSNSMREDIANCIERSF-KYLTLKEAQKVLQVDQLSEYIKKR-GWKVQLIHQTIHYAKELERIV Pucgr2 TIAQLLLKLKLAQSSLAKARDILEIGAFYSVRPAFERYISQLGSYYLVGLDLLRLLSQNK--IAQFHTVLEGLNQYISHPVNLERWLMEGSYSKVWDLLVDTIRNEIASCQEKAY-SSLPLNDAGTLLFFGEVIEFAQQR-KWLVKIIETTLGYAKELETIV Punst1 RCGELLTKLKMIENGLVVARTILEIGAFWSIRPSFDRYFSQLQTFYIRGLQLTRLLTQNR--IAAFHAALESLNPYIRHAVDLERWMMEGSYAKVWDSLMGTIRNEIASCEEAAY-DSLPLKDAATLLFFSELQNFARER-GWQIKLIAQSLAYARELEQIV Rhior3 KIGQLLNQAKLIEAGLIAARDILEIGAYYSVRASFERYIAQLNTYYLIGLNLLRLLSQNK--LSEFHTTLEGINPFIKQAVDLEQFLMEGSYNKVWDILMNTTRHEIANCSERAY-EYLPLNDACTLLFLEELLSFANER-GWKLQTITRTLGYAKELELIM Rhoto1 KIRSLLAQLKLSELGLTTAREVLEIGALFSIRPAFERYLSLLSAYYILALSLLRLLSQNR--IAEFHTLVETLSKEVGWVMQLERCLMEGSYSRVWSTLLSTVRSEIAACDERAY-ESLPLRDAKTLLFFAEVKEFAKQR-NWHLKVVEATLRYTKELETIV Rozal11 KCGQYLSVLKLIPQVLVVARDVLELGALWSIRPSFERFYNQLKTFYIFGLYLLCLLSQSR--IADFHSAIELINPFVRHPVQLEQYLMEGAYNKVWDILMETVRAEIATSIENAY-DYLPLQNAANLLYFNALNAFIKQR-NWNVEVYKKTMEYARELEKIV Sacce1 ACEKLLPPIKLIKNNLMITKRILEVGALASIQDSFENYFNQLKPYYLISLYLLNLLSQNN--TTKFHSELQYLDSLLSYPIKLDRWLMEGSYQKAWDILKSAIRDEIAKNTELSY-DFLPLSNIKALLFFKETEKFALER-NWPINIIEKAMDYAISIENIV Salro ECQSLLTQMKLTEISLVLARDSLEIGAFWAIEATFERYMKQLKVYYLLGLDLMHLLSQNR--IADFHTALERLNTYIRHPVELEQYLMEGSYNKVHHKLMGTIRHEIASCCESAY-DSLKLEELKSLLYTAEIDTIIKAHPDWDVTIIDRTLTYAKELETIV Schco3 KCGTLLTQLKLIENGLAVARDILEIGAFWSIRPSFDRYFSQLQTFYIRGLNLIRLLTQNR--IADFHATLESLNPYIAHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-DSLPMKDAATLLFFSELMNFATSR-GWSVKLIHADLMYARELEQIV Schpo1 ACKKELLKLKLAKQNASFARNVFEYGVLVSIQESFARYASQVIPFYVTGLNLLYLLSENR--IAEFHTALESVDPYVEWVISLEQNVMEGAFDKVAKIVMSMVRNEIATCAEKVY-SEIPLSNATSLLYLKETEKLAEER-GWDISSIRQLLSYTSELEQIV Sorma DSSALLSKAKLLQLNFSLARQVYEQGALASIRDAFLRYVSQLQGFYVTGLYLLLLLTQGQ--YAEFHSELEALDRYLGYPIKLERWLMEGSYDRVWEILTFQIRSEIASSSERAY-PSLPISSTKSLLFLGEVVEFARSR-GWVLLVIENALGYARELETIV Sphar KVGKLLTQTKLLSIQMLLARDVLEIGALYSNKNAFERYFLQLKTYYIVGMNLMRLLAYNE--LSLFHTELEVLIRCVAYPVALERYLIEGAYNRIFEKLAVTVR-------------------------------------------------YVYEITRH- Spipu1 KCGQYLANLKLTELSLLLAREVLEIGAQWSIRPSFERYISQLKTYYLLGLNLLRLLAQNR--ISEFHTELELINVYIRHPIQIEQCLMEGSYNKVWDILMGTIRDEIASCSEKAY-DSLPIADAATLLYFDEVTAFASER-GWKVKVISQTLEYARELERIV Sporo1 KLTSLLGQLKLAQLGLSTAREILEIGAIHSLRPAFERYLSLLESHYITALNLLRLLSQNR--IAEFHTVLETLSKPVDWVLQLERSLMEGSYSRVWQPLLETVRSEIAACDEKAY-ETLPLVDAKTLLFFDQVKAFAKSR-NWYLKVVSATLLYAKELESIV Stehi1 KCGQLLAQLKLIENGLVAARDILEIGAFWSIRPSFDRYFSQLQTFYIRGLNLIRLLIQNR--IADFHTTLESLNPYIRHPVNLERWLMEGSYSKVWDSLMGTIRNEIASCEEAAY-ESLPLKDAATLLFFTELMNFAQQR-GWQVKLIANNLAYARELEQIV Tapde11 ------------MVDITALKKLLEKSALASSKEGYKKNYQQLKPLYIIALHLLILLSESN--ISQFHSELESLAE-VQWVRSVEQGIMEGSYQEVRSLMTESIRADIADCSASSY-TSLPLVNLTTLLLLKETEQFAGER-GWLVLLITQTLGYARELESIV Thetr KCTKLLNELKLVEEGGETARAVLEYAVLLAVKEAFERHMTQLAAYYMVSLHLLHVLTRDSEYPAPFHMLLETLNPQVAAVVELEQLLNDGRYANVINKLRDAVKAEMAACVATAY-ADMPVARAKTLLVCAELAELAAD--GWLIRVISDMLGYARDLERIV Treme1 DVTKRLSKLKLAQSGLIATRSILEVGAFHSLRKQYWQYNSSLQPFYTLGLHLLALLSEGR--LTDFHTVLETLDSFVKLPVDLERWLMEGAYNKVYERLMGTVRAQIAATIEASY-PSLPLDSAASLLFYSQLANFCTER-GWSITMVGPALKLAQQLEAIV Trire2 EASALLSKAKLLSLKLALARETYEQGALFSIRDAFTRYVQQLQPFYVTGLSLLLLLTQGR--YAEFHSELESLDRYLGYPVRLERWLMEGSYDRVWEILKNQIRSEIASSSERAY-PSLPISSTKSLLFLGEVIQFAKHR-GWVVMIMENTLGYARELETIV Umbra1 KCAQMLTQLKLTEIGLVLARDILEMGAYYSVRDAFVRYISQLSTFYLTGLNLLRLLSQNR--LSEFHTALEVINSYIKHAVDLEQFLMEGSYNKVWNILIDTIRHEIANCSEKAY-EALPVQDAATLLFMEDVLNFAQER-NWKVQIIKQTLTYARELERIV Ustma22 -VRSLLTKLKLTENNLVLAREVLEIGAFYSVRAAFDRYISLLTPFYLLGLRLLRLLSSNQ--ISAFHTLIETLSKFLQHPVSLERWLMEGSYSKVWDLLMDMIRNEIASCEEKAY-DSLALHDAATLLFFEQVLGFAQSR-GWQVATIANNLVFAKELESIV Walse1 NVKSNLTRAKLAQLGLADLKDILEYGCHYSIRSAFESYLNLLKPIWIISLQLLIQLIQNK--ISDFHTLLETLSHEISIPVKLERFIMEGSYSKLFDQLLFTIRNQIALSQETAY-QSLPINDAATLLYFSELMEFSKQR-GWSVNMISHSLNYAKELESIV Zygro1 SCQKLLPAIKLIKNNLNVAKSFFEIGALVSIYESFQNYFAQLRVFYILSLYMLILLSQGE--ITKFHSELEFLDELLSYPIRVERWLMEGSYQKAWGTLMNAIREEIARNTEMAY-EKLPLSNIKVLLFFKEAEHFAVQR-GWKVHLIEKTLNYAINLESIV [Cluster1875.fasta_al_trimmed; alignment length = 162] Allma1 -MFDTIPELRGKRVVLASKSPRRVELLQQQ-GDVIGSTFAED-LAHHHFHYVVTNAREKALQV-YRSLADLVIGADTVV-V---TMLEKPSSRVATLRRLRDVVTGICLVEDISNYVNTDDPMDKAGSYGYQ-AA-CLIAGIDGCYYNVVGLPLHRLAAVRE Ashgo11 --MSLIKGIEREYVILASTSPHRYSIVTEVLGAVMKPNFAED-LDKGSYGYVEDTCKGKTTNA-IQQLPKLVICADTVV-LGADVINEKPGNSDRMLHSFC-VVTAVRIVALLNAYVASGDGLQVAGGFKIQ-PA-TMIRKINGDYYNVVGLPANRTRATGR Aspfu1 LSLPVLNHLRTKRVILASASPRRRQILSLL-GEVIPSDAVED-FPK-T-EYVLATATKKAQAV-YSAEPALILAADTVV-VDNLSILEKPRSEAAMLKMLRDVYTAMVAMDLIVAYVRTREGADKAGGYGLQ-GS-ILVESIQGSWDNVVGLPLKAAKVMAK Aurde31 LAMPGTTKLHGKRFVLASASPRRKQILETF-GEIVASEFAED-LSHGAFEYPTATATEKAVAV-YVKLPDLVIGADTIV-LAH-EVLEKPNSKTRMLLDLNGVVTGVTVVALLQAYADSGEGADRAGGFAIQ-GG-ALIAKIDGDYNNVVGFPGASFLLVEE Batde5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Botbo1 LPIPVFNKLFGKRVVLASASPRRKEILNTY-GEIVPSTFEEN-LSKDDFEYPVSTATEKAVEV-YERLPDLVIAADTIV-LTR-EVLEKPGTKERMLLDLNGVVTGVSIVHLLEAYVDSGEGIDRAGGFAVQ-GG-LLIAKIDGDFWNVVGFPAASFLLIEE Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel --------MKEAIIVLASQSPNRLKLLQQI-GIVKVSNFEEN-LPKT--QFVIETAKGKLTTI-VEEMYSVIIACDTVI-EFNGEIIGKPTDANETLKRLRNVYTGMALHRVIDEYVKSGEPLKKAGSYGIG-GA-VFVRGIEGCMPNVVGLPLHRL----- Canalb1 FNHPLIAKL-KNYLILGSTSPRRQEILKTNLGGILGSNFAED-LSKDDKEYVQLTSKHKAEAI-VASLATLILTCDTII--SCNKVFEKPITKEQFFNYFK-VISALTLIEIINAYIESEEGLEVAGGFKYQ-GG-LLFESIDGDYLNVVGLPLK-TRSI-- Cangl ----MLSELLESYFILASSSPRRYEIIHDILGDTMKPSFEED-LDKSKYQYVIDTCKGKADGI-CDDLPQVVICADTIV-LDANKIYEKPSSRNKNLHWFCYVVTAVSVISFIEEYSRNDAALNAAGGIMIQ-CG-AMVNRIDGDYYNIMGLPLNKLRLL-- Capow MLLDLLTKLERFEFVLASSSPRRRDILNSI-GLIAPSTFAEN-LDKSVYRYALDTAEQKALDV-QAQRSEIIVSADTIV-ESNGLIMEKPAHAEQMIKQLSGVHTGVVIIDLIRAYVQTGEPMDKAGGYGYQ-AG-SLIAGIDGCYYNVVGFPLHSFQMTPQ Catan2 -MIDI---LKDKKVILASKSPRRVEILTKL-GTAVGSTFPEL-LAHDDFDYAMTNAREKALEV-YRTLPDLVIGADTVV-VYEPIILEKPNDEAQMLITLRNVVTGMCFVAMIDAYVATGDPLDKAGAYGYQ-AM-FLVERIDGCHFNVVGLPVYRMHHIK- Cioin ---PLRELLRNLKVVLASSSPQRRKLLEQI-EDICASPYDEEAIDKTSFDYVKLLAHGKALEV-ANQHKVLIIGADTVI-IFENKIIGKPHTAQETLNKLSGVCTGVSVIEMVQSYVDTGEPLNKAGAYGIQ-GA-MFVQRIEGCYNNVVGLPVYKLKFLDN CocheC53 LSLPALNQLRGSRVVLASKSPRRRQLLAQL-GDVCPSQFAEN-LDH-S-NYVLETASAKALDV-YKAEPAIVISADTII-VSHDRILEKPRSEAGMLKMLRDVMTAVVVMELILAYVRTRDGNDKAGGYGIQ-GS-VLIERIEGSYDNVVGLPLRATNVMQP Coere1 LRIPFVGELAHRFIVLASASPRRKELLNRL-DETIPSNFPED-LDKSQFDYALENAVRKANDV-YLKIPLLIIGADTVV-LNDNAILEKPASQDTTLKGLSGIFTGVCLVALIEAYVATGDPMDKAGSYGYQ-GF-LFVKEIKGEFYNAAGLPCARIDIYNQ Conco1 -LNKLVEPLKDYKIILASGSPRRKEILTNL-GKIIKSNFEED-LPHDSFLYCMETAKQKCLEV-YHRLKGLIISADSIV-VKDNKILEKPLSEQDKLSMLRGVISSLVLIQDLWAYIETKEPMDKAGGYGYQ-AS-LFIPKINGCYFNVVGFPIHKFKVFSQ Conpu1 LKTPATLKLIGKRVVLASASPRRQQILENL-GEVIPSTFEEN-LSLSSFEYPVATATHKAVEV-YQRLPDLVIGADTVV-FTH-ELLEKPSSKQRMLLDLNGVVTGVSLVAFLQAYADSAEGIDRAGGFAVQ-GN-LLIRKIDGDFQNVVGFPAASFILVED Copci LKTASIEKLKDKRIVLASNSPRRKEILRTI-GDIVPSTFQEN-LPISGYEYPVATATHKAIEV-YERLPDLVIAADTVV-LTH-EVLEKPRDKERMLLDLNGVVTGVVVVSLLEAYVENGEGIDRAGGFAIQ-GS-VLIRKIEGDYNNVVGFPVASFMLVEE Croqu1 LKLPIFEKLSGKRIILASSSPRRLQILQSI-GEVIPSQFKED-LDQNSFRYAAATATEKAIEV-YRRLPDLVIGADTIV-QTY-KILEKPENKSSMLEDLVSVITGIVLIEDLIAYVENGEGFDRAGGFAAQ-GC-QFIRRIDGDWNNVVGFPAYAFNLLKD CryneH991 ------------------------------------------------------------MEV-YERLPDLVISADTVV-VF--EILEKPINKDRSLALMSGVITGISIVQTIQAYVDSNEGIDRAGGFAIQ-GG-ILIEGIEGNYDNCVGFPSAPFELDAD Crypa2 FELPIISHLKGKRVILASSSPRRKALLAQV-GEIKASTLPED-LDKTA-EYVSATARRKCMSV-YEAAPELVIAADTVI-VSNERVLEKPHSEARMLRHLRDVLTAVVCLDVIDTYVKTREGADKAGGYAVQ-GGLVLVEKVEGCVDNVVGLPVRKTKVIFQ Debha1 FNHPLYDWL-KQFFVLASTSPRRLEILQKNLQTIMPSNFEEN-LLKEEHEYVSNTSLGKGQAV-MKQLSSVIVSSDTII--TCNEVFEKPQTKEEMFRKYC-VITSVNVIEFLQYYVDSEEGLHVAGGFKYQ-GC-LLFKSIEGDYFNIVGLPARTTD-ILQ Dekbr2 FDHPVYQKLADYKVILCSTSPRRKDILEQL-GEIAESHFEEN-LDKSKYEYVRETATGKAKAV-WNSLKILLIAGDTVV-----KIYEKPQDYQEMLKELRDVRSGVVLLEFIELYCRTGEGLQVAGGFRIQ-GI-MMMKGVKGDFYNGVGLPSTKTCVV-- Dicdi MILDILVKLNKLKIILASTSPRRIEYLGKL-GEIVESKFKED-LDKSQFDYCLENAKLKAIHA-GIQLPNIIIGSDSIV-VYDNKIFEKPKSLESMLTLLSGVCTAVHIEELINYYVDNFKPLDKAGSYGIQPAA-SFIKSINGDFYNVTGLPIHDLKIYVD Dmel MLAPIKHLLGNYRIVLASGSPRRQELVKML-GELCPSTFEEN-LNLEDFDYIEATALGKAEEV-YSRLNLIVIAADTMV-TLGKEIYGKPKDPARMLTNLSGVFTGVVLKEQIQSYVDSGDPLDKAGAYGVQ-AG-ALIHRIDGDFYCVMGLPLHRLKLFLE Enthi MLLEYLNTINSKKIILASQSLRRKEILEQM-EEIHVSNFEEN-LDKKLFDYVKANAEGKVMDV-ASRYADLIIGCDTIV-LFNNEIIEKPKNAERILHKLSGVISVVCLVTFINKYIESGYCYDKAGGYGIQ----TFISRIDGSYWNVVGFPSFKFEVVKK Falba ------MPLKDAAFILGSKSPRRIQLL----GVVQPSAFEED-LAKEASAYVSATCWGKMTDL-LPGLYEIVICADTVV-VLPGQIVEKPADEGAMIRTLCDVLTAVACADTIRAFIAQSHPYDKAGGYDIQ-SRMIIRGSRDGLASTVIGFPIEAFALF-- Fomme1 LKVPGLVKLSGKRVVLASASPRRKEILANF-GEIIPSTFEET-LPQSSFEYPVATATQKAVEV-YERLPDLVIGADTIV-LTH-EILEKPISKARMLLDLNGVVTGVSLVHVLEAYADSGEGLDRAGGFAVQ-GG-VLVRKVDGDYNNVVGFPAASFSLVEE Fusgr1 LELPILKHLNSKRVILASASPRRKALLQQF-GEILPSTKPEN-LDKAA-EYVAATAHQKCMDV-YTTAPDLVIAADTVI-VTKDRILEKPRSEARMLKHLRDVLTAVTVLDVIEAYVKTREGADKAGGYAVQ-GGMLLVEKIEGSVDNVVGLPVRKCKVIFR Galma1 LRIPALEKLKGKRIVLASNSPRRKEILRTF-GDIVPSTFEEN-LDISQFEYPVATATHKAVEV-YEKLPDLVIGADTVV-LTH-ELLEKPTSKQRMLLDLNGVVTGVTVVHIVEAYVESGEGIDRAGGFAIQ-GG-MLIRKIEGDYNNVVGFPAASFLLVEE Ganpr1 LQLPCVQHLNSLSIVLASASPRRKDILDKL-NKIIPSTFPET-LDHSAFAYALTNASEKAKDV-YRTLPLLIISADTVV-VTLDTILEKPRDADAMLKKLSGVVTGVTLLPWIDAYVESGDGSDKAGGYGYQ-GL-FLATSIEGCAYNVAGFPAHDFQIIKD Gloin1 F--AFVQHLKNKRIILASGSPRRREILSRL-GDIVPSKFPET-LDKAKYEYAIANATEKGLEV-YGRLVDIVIAADTIV-SIDDDILEKPKDAERMLKRLSGVYTGVAFIDDLKVYIETGEPMDKAGAYGYQ-GS-FFVEKINGCYYNVVGLPI-KVKLVKK Hisca1 LALPTLIDLRSKRVILASSSPRRHQILSYL-GEIIPSSFAED-LPK-T-EYCLETAVRKAQAV-YRQEPALILAADTIV-VDPTQILEKPRSEAAMLKALRDVYTAMAAMELILAYVRTREGVDKAGGYGVQ-GS-ILVERIEGSYDNVIGLPLRATKVMMI Klula1 -MNPLSQKLTDKYIILASSSPRRFEILTEQMGKVMKPSFEED-LDKSLYDYVQDTCKEKAKSI-LQELSKLVLCADTIV-VDHTEIYEKPVEKERNLLRFT-VITAVTIISIVEMYVESGDGLQVAGGFKVQ-SG-CLIKKVNGDYYNVVGLPLNGTTLI-- Lacbi2 LAVPAIKKLAGKRIVLASNSPRRREILHTF-GDIVPSTFEEN-LPVSSFEYPVATATHKAVEV-YERLPDLVVAADTVV-LTH-ELLEKPQSKARMLLDMNG------VLHIINAYVDSEEGIDRAGGFAIQ-GG-ILIRKIEGDYNNVVGFPAASFLLTEE Lenti61 LKIPALEKLVGKRVVLASNSPRRKEILKTF-GEIVPSTFEET-LPFSAFEYPVATASQKAVEV-YERLPDLVIAADTVV-LTH-DILEKPTDKDRMLLDLNGVVTGVSVVSLLRAYVDSGEGIDRAGGFAVQ-GG-MLISKVDGDYQNVVGFPAASFVLVEE Malgl1 -------------------------------------------------EYPVETASEKAKEV-YVRLPDLVIGADTVI-VY--EILEKPVDKVRMLADLCGVITGVALVPLLQAYVESGEGLDRAGGFAIQ-GA-LLIRGIEGDYNNVVGFPLYSVNLVEN Mellp23 LKLPIYNKLRNKRVILASSSERRINLLKSI-GEVVPSTFKED-LDHETFKYSLTNSTEKAIEV-YTRLPDLVIGSDTII-QSY-IILEKPTSKSKILKDLVTVITSVTLVEDLLAYIENGEGIDKAGGFAIQ-GS-QFIKRIHGDYNNVVGFPIYAFSLINE Mnele --MAADSLFSKHRIILASASPRRRELLQQI-AEIIPSKFEEN-LPKSSFDYAIATATGKASEI-YKEHEAVVIGADTVV-VVDNKILEKPSDVASMLSELSGVVTGVCICDLIDWYVGTGEPLDKAGGYGIQ-GA-ILVERLAGCYFNVVGLPLQKLKILSE Monbr -MFRSAS-LATGGMICDSSRPRRTSSAAMV-SVVESSRFDEKSLDKASYAFVEDNAMHKAREV-ASRLADIIIAADTVIHLPSGQIMEKPVDAAAMMRSHSGVTSGVALGDEIAAYVATGDGMDKAGGYGIQ-AA-VLIESIQGDYYTIVGLPVHQLNVVST Morel2 LNVKWLNSLNTKNVVLASSSPRRKDILSQL-GTVVPSTFPET-LDKSLFDYVKENALQKALEV-YERLPDLIIGADTVV-AHGSKILEKPESVEDMLTSLSGVYTGVTLIELIEAYVATKEPMDKAGAYGYQ-GS-ILVKGINGCSWNVIGLPASKVEFTSE Mucci2 LNLPVLNNLSKKTIVLASASPRRREILTDM-GSVVTTLEPDE-NDPTAYEYVSDTAYMKAKEV-FERCADIVIAADTVV-VKDECVLEKPKDKDEMLQQLNGVLTGVQIMEIIQAYVDSGEPFDKAGGYGIQ-AS-LFVESIHGDYWNVASIV--------- Mydma -MIHVVKHLLKDFIHLASASPRRKTILNHV-GTVTPSTFDETSLDKKKFEFVMECAKQKALNV-EKRLKRIVIAADTIV-VSNGEILEKPHTKELMLTRLNAVYSGVAMI-------------------------------ITG------------------ Neucr2 LQLPILDHLRTKRVILASASPRRKALLNQL-GEIFPSDKPED-VEKGK-EYVAETARRKILHV-YEQAPALVISADTVI-ATRSRILEKPRDEQRMLKHLRDVLTAVCVLDVIEAYVKTREGADKAGGYAIQ-GGMVLIDKIEGSVDNVVGLPVRKTKVIFK Orpsp11 FKLPFLQKFKENELVLGSGSPRRKEILSKL-GIVDPSKFDESILDKSHTDYVRRNAIEKSLEV-YCRRI-IVVGADTVV-SCQNKILGKPNSVEITLKNLRGVYTGVSILEVIDAYVATGEPMDKAGSYGYQ-SA-FFIEKINGCYYNVV------------ Pench1 LNLPVLNSLRSQRVILASQSPRRKQIMSFL-GEIIPSNAAED-LPK-S-EYVLATATKKAQAV-YEQEPALILAADTVV-VDPSSILEKPRSEAAMLRSLRDVYTALVAMDLIMAYVRTREGADKAGGYGLQ-GS-ILVEKIDGSYDNVIGLPLKATTVMQR Phybl2 LELPLWDNIKGKRLVLASASPRRKEIMEDM-GDVVTTLAPDE-NNPANYEYVADTALMKAIEV-FGRCADIVIGADTVV-VIQGKILEKPRSEQDMIGQLSGVLTAVQILVVQEAYVRSGEPFDKAGGYGIQ-AS-LFVESINGDYWNVVGLPKNHLLL--- Picst3 FRHPLYEKL-SQYFILGSTSPRRLDILHNNLNTIIGSSFEEN-LTKEGIEYVRQTSRGKAESI-LTDFATLILTSDTVI--SCNEIFEKPGTKEHMFEKYH-VITAVTIVELVDAYINSEEGLQVAGGFKFQ-GS-LFFKGIEGDYFNVVGLPVATTQAVLK Plicr1 LPVPSTKKLAGKRIILASASPRRQEILKTF-GEVVPSTFEEN-LGIDEFEYPVATATHKAVEV-YERLPDLVIAADTVV-LTH-DLLEKPVDEERMLLDLNGVVTGVSIVHLLRAYAASGEGRDRAGGFAVQ-GG-LLVRKIEGDYHNVVGFPAASFLMVEE Polpo MILDILEKLNKLNIVLASGSPRRVEYLKLL-GKVVPSTFEEN-LDKSKFDYAVTTAKHKTEDV-YQKLPNIIIGADSIV-VLGDTILEKPKSIEEMLAGLSGVYTGVHLIELIAYYVDNYKPLDKAGGYGIQAAT-SFIKSINGCYYNVTGIPIHRLELYHK Pucgr2 LKLPLYTKLTRKRLVLASSSPRRLKILRDI-GEVIPSRFEEN-LDHSSFRYAAATASEKAIDV-YTRLPDLVIAADTVL-QTF-KILEKPDSPASMLEELMNAVTGVAIVESLVAYVSQGEGIDRAGGISIE-GS-QLIRRIDGDWNNVVGFPAFAFKVMAE Punst1 AALPSLKKLAGKRVVLASNSPRRREILRTF-GEIVPSTFEEN-LPVGSFEYPVATATQKAVEV-YQRLPDLVIAADTVV-FTH-DLLEKPTSKERMLLDLNGVVTGVTLVHVLKAYVDSGEGLDRAGGFAIQ-GG-MLIRKVDGDYNNVVGFPAASFLLVDE Rhior3 ---------------------------------------------------------MKAKEI-FERCADIVIGADTIV-VKDEQILEKPRDKEYMLNQLNGVLTSVQIVEIINAYINSGEPFDKAGGYGIQ-AS-LLIESIEGDYWNVVGLPKNRLRIANV Rhoto1 LRLPVFNKLKGKHIVLASASPRRNEILRTF-GRIVPSTFPET-LSHAEFQYAVATGSAKAVEV-YQQLPDLVIGADTVV-ILP-TILEKPRNKANMLESYQGVVTGVTIVELLQAYVECGEGLDRAGGFAVQ-GG-LLVKRVEGDYNNVVGFPGQAFQLTEE Rozal11 IEKLGIRKLSEKPVYLASKSPRRIELLQRLAGVIKPSLFKEN-LKHSDFGYVLATCEAKANEV-LNRIFSLLISADTIV-SLNRTIFEKASDRSTMLQSLSGVYTAVTLMSAIEAYLDTNEWQDKAGSYAIQ-SS-FFIEKINGDFYNIMGFPCCRFYLFNE Sacce1 LPPDVIGFICSKYIILASTSPRRYEILHDIMGKTMVSTFEEN-LDKMNYGYVCDTSWHKAQNI-IEILPKLIICADTII-IDKSRIYEKPKTKEKFLMKFCYVVTAVTLIRILEEYVESGDGLEVGGGFKIQ-GA-ILIEKIEGDYYNVVGLPLNKTAEANS Salro MLFHALEWLNAQRIVLASGSPRRSELLSML-RTVNKSQFDEKSLNKSDFAFVQTNALRKAEEV-AERMFDLIIGSDTVV-VQDDRILEKPESDEEMIRHLAGVATGVALIEEIRAYVATGDGHDKAGAYGIQ-AG-ALIESIQGDYYTVVGLPLHALAWADG Schco3 LPMPSIKKLKGKRVVLASASPRRKEILSRF-GEVVPSTFEEN-LPVSSFEYPVATAQHKGVEV-YERLPDLVIAADTVV-LTH-EILEKPVDKERMLLDLNG------IFALVKAYVDSGDGLGKAGGFGVQ-GG-LLISKVEGDYNNVVGFPASSFILVEE Schpo1 TS--MHRQLKDKRIILASGSPRRKQLFEQM-GETCVSGFPED-LNKSMYEYAADTSVQKAIAV-YEKLPDIVVSADTIL-I---EIMEKPNDPKAMLKKLRNVFTAVSVIEFLEAYVRCGEGSDKAGGYAIQ-GA-LLIESIIGDFSNVVGLPIRATEALEQ Sorma LQLPILEHLKTKRVILASASPRRKALLSQL-GEIFPSDKPED-VQKGK-EYVAETARRKILHV-YEQAPALVISADTVI-ATRSRILEKPRDEQRMLKHLRDVLTAVCVLDVIEAYVKTREGADKAGGYAIQ-GGMVLVEKIEGSVDNVIGLPVRKTKVIFN Sphar MILPHLSVLNSKRIVLASGSPRRKELLDKL-GEIVPSIFEEN-LDKDDYDYVRQTSIHKAKEV-FARLPHIIIAADTIV-EHNSTIFEKPSSKESTLMDLSGVWTAMTILELVHEYVESGEPMDKAGGYGYQ-GF-QLVESINGCNFNVIGLPVHSF----- Spipu1 -MLPAIAQLNTRNVILASGSPRRKEILERL-GNINPSTFPED-LNKTIFNYVTRTALEKGLQV-YQSLNPLVISADTII-VLDDQILEKPVDAARILSSLSGVLTAIVVVAVIDAYVETGEPMDKAGAYGYQ-AS-AFIPRINGCYYNVVGFPCHRF---DD Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 LRIPGLNKLHGKRVVLASGSPRRKELLETF-GETIPSKFEED-LNPHDFEYPVATATHKAVEV-YERLPDLVIGADTVV-LTH-ELLEKPDNKARMLLDLNGVVTGVTVIYLLEAYADCGEGLDRAGGFAIQ-GG-MLIRKVEGDYNNVVGFPTASFLLVEE Tapde11 TAAQLFPTLVGQRIILCSSSPRRLALLTQL-GEVIASGFEEN-LSKSDYEYATATATEKILAV-YRSVPRLLLASDTII-L---QILEKPTSPDAMLKQLRGVFTAVAALDVLVEYVKSGEGSDKAGGYAIQ-GA-VLVDKIEGSYDAVVGLPLNATEVL-- Thetr MILDILPLLRSYKWLLGSSSPRRAEILASL-GDTASPSFAE-DLPKEAFAYVLATAHGKADALEADGAYDVVVVADSVV-VLEGAVLEKPADADRMLTALSGVHTAVVIVELIAAYVASGEPLDKAGAYGIQ-GG-TLVAAMDGDYFTAMGLPKHALTWGPD Treme1 LPLPIFRQLSNRRVVLASSSPRRRDILELA-GEIVPSTFAED-LPKSQFDYPVATAGEKATEV-YERLPDLVISADTVV-IF--EILEKPFSKDRILSSMSGVVTGICIAELIQAYVDSGEGIDRAGGFAIQ-GG-LLIERIEGNYDNAVGFPSAPFELAEE Trire2 LDLPIIKHLNSKRVILASASPRRKQLLQQI-GEITPSTKPED-LDKKT-EYVATTARNKCLEV-YSTTPSLVIAADTII-VTRDRILEKPRSEARMLKHLRDVLTSVCVLDVIESYVKTREGVDKAGGYGIQ-GGMLLVEKIEGSVDNVIGLPVKKTKVTFQ Umbra1 LNVPHLQRLKSKRVVLASASPRRREIIRNL-GDVVPSLFPEN-LDKSTFGYVSETSKGKALEV-YQRLVDLVIGLDTIV-VIDDRILEKPGTPEAMLKSLRGVYTAVTFVQVLQAYVDTGEPLDKAGGYGYQ-AS-FLIKKINGDYWNVVGLPTCRLTLCEA Ustma22 LATPLFNKLAGKRVVLASSSPRRKDILASV-GEIVPSTFEEN-LPKSEFEYPVHTGSKKALEV-YERLPDFVISADTVV-VK--VIMEKPTDQHRMLADLNGVVTGVTVIYMLKAYVDSKEGLDRAGGFAIQ-GS-LLVRSIEGDYNNVVGFPLYAFDLLEH Walse1 FRLPSLDKLKDKHVILASASPRRLDILAQV-GRVIPSTFEET-LSKDDYAYPINTATEKGKEV-YERLPDLVISADTVV-LVPDSICEKPKDADRMLADASGVVTGVCITDVIEKYIETGEGIDRAGGFALQ-GS-LLIQGIEGDYNNVVGFPLSEFTLIEN Zygro1 MINRVIESIVSQFIVLGSSSERRYEILQQVMGTIMKPSFEED-LNKSEFNYVIETSRHKALGI-VNDLPKLIVCADTVV-IDSQNIHEKPQYKEKNLKKFCYVVTAVTVVDLLEDYVASGEGTQVAGGFKIQ-SA-VFIKKIDGDYYNVVGLPLNKTRELQN [Cluster1882.fasta_al_trimmed; alignment length = 351] Allma1 EIRRREKEQFVSGLTGTSMEEVHRV-MLVAVFSY----LALKLLEFAAVLWPDVLAHRATVAVTF---------KPAVTVYRALMMSLTCFAILAVDFH-VFPRRFAKTEVFGTSLMDLGVGCFVFSQGLTVL-------K---VWSSIR-RGWPLWLLGLGRVISVKGLDYQEHVSEYGVHWNFFFTLAALGPIVVFLDRWAMLL---IDYEVLL----GLQHYVLAP-R-TNLISA-NREGLASLFGYVAIFL--AARHVGLCNAPFVLWTVVV-NAGMV-ALLV-----AEVADAVNANGLVVFLGANLATGTVNMVMDTLRV-PAVAVLVAYMGSVVLV-----MRW Ashgo11 A-LKERKEAFVSGLEGGSIAEINLV-TTVALTAYFGQLLNRR-VDFLLNWAGLLL--SITLNLLIAVPCIVQLQKPFITAYRGGMLIITCLAILAVDFP-VFPRRFAKVETWGTSLMDLGVGSFVFSNGLVAA-SALLKQEWSRLVSSVR-SAGILLALGVARLVSVKGLEYQEHVTEYGTSWNFFFTLALVPLAMILVDPIFIALLLSVFSEYLLQK-EGFLQFMISK-R-DNFFNS-NREGILSFLGYCAIFL--LGQNTGFANLPYVLWVAAY-NLGFLSMYCM-----PVTLDAVNSNGLFVFLLANCLTGLINMNMNTLDS-TQIAALFGYATVIASVACRIFIKL Aspfu1 PDYKARKEAFVSGLAGGSILEINAV-TLVASVSVFLSILQS-LVDFLLNVLAILF--ATTLNLLLISPALLILLHPFLTTYRAAMMVITCIAILAVDFR-IFPRRFAKVENWGTSLMDLGVGSFVFSGGVVSA-RSLLKSRAKRLIASTR-HSIPLLVLGLIRLYSVKGLDYAEHVTEYGVHWNFFFTLGLLPPFVEVFDALVLSVGIAVLYQVALES-TDLKSYILSP-RGPSLLSK-NREGVFSFSGYLAIFL--AGRAIGLANMPYVLWVSAF-NTAQLFVFCLESESESRIMSAFNKNSLAIFLLANLLTGAVNLSISTIDA-NAIAVLIGYSSIITGVAANIKVLP Aurde31 HDYKAAKEAFVSGVVGSSITQINLI-SLVSFISLGIGDVVRRALEWVILALPILL--SITLVVLTLAAQWP-LSLAALTAYRSHMMLLTALAILAVDFP-VFPRFLAKCETFGTSIMDIGVGAFVFSQGVVSA-APILK--LRKLTIVIR-KVMPLALLGIIRVLLVKGTDYPEHVTEYGVHWNFFITLAILPPLQVLLHGLFLAVTIAGLHQLALSY-TPLQNYALAA-R-TDWLSM-NKEGIISLPGYLAIHL--LGLTTGLANLPYVLWTAAY-NTSAILIYILIVP--PVLLEAINRNGLLFFLLANLCTGVVNLSIRTMYA-GAMVVLSSYSVAICYVA-GRRLIN Batde5 ------------------------------------------------------M--SITLAAQIAAVLGFIALKTAVSGYRAFLQMLTVTAILAVDFS-VFPRRFAKTEMYGTSLMDIGTGAFIFSSGLV-S-GPRINQKSQIV--------IFPVLFGVLRIAFVKSVNYQEHVSEYGVHWNFFFTLACVSLLATLHGTLFTAVIIIIGYEIALAR--GLEQYIIAP-R-VDIISM-NREGICSMAGYYCIFL--ISAEIGLANASYVFWVTAV-CTSLLAGLFV-----PVLFQSLNRYQLVAFIVANILTGLLNLSINTLQV-SAMGILFVYASIVSSSV---TWK- Botbo1 SSYKSEKEAFVSHMTGSSIAHVNAI-SSVALFSIVLSALQSRLSEAAVLVAPVVL--SITLAILLGLPASA---LPFISVYRAHMMLLTILCILAVDFP-VFPRSLAKCETFGVSLMDMGVGSFVFSQGLVSA-IPLLK--FPKLAESLR-KVWPVLLLGLVRVVLVKGTEYPEHVSEYGVHWNFFITLGLLPPLSVLLHPLLIGLLITLAHQVLLSG-TQLQSWAIPE-R-VGLLGM-NKEGIISMAGYLAIHF--LGLSTGLANLPYVLWVVAF-NTLFLLGYLL-----PVLLEAINLNALPLFLLANVMTGVINMSMQTMYA-SALSVIGAYVGVMCAVA-ERRWVR Botci1 ASYKSLKEEFVSNLTGGGIGEINMV-TAVAPVAVILSALQS-AVDFLLNVGAILL--AISLNLLLLAPVPLLYAKPFLTIYRGAMMVITCIAILAVDFR-IFPRRFAKVENWGTSLMDMGVGSFVFSGGLVGA-RPILKEQSTRLYNSIR-HALPLIALGTIRLYSVKGLDYAEHVTEYGVHWNFFFTLAFIPPFVAIFQSALLAVILGSLYQVTLEY-TSLKAFILAP-R-TDLFSK-NREGIFSFFGYLAIFL--AGQATGLANLPYFLWVSAF-NCSQLTAFCLKTEKESRVLEAFNRNGLAIFLAANLLTGLVNLTIPTLFV-SAMGILLLYASALTGLAYDISIKM Caeel VGATTEHSSFVGTLTGCAQRELFLT-FLITMLGLFIIFLGRRVADVIFLCVPSLL--AMTLSTIMIIISAVLLITQFVTYFRSLTMILVTLAILAVDFP-IFPRKYAKTEKFGHSMMDVGVAAFLFQAALGSSSGRQLSHH-------LS-STFLLFALGAGRAVLLEVIGYPQHVTEYGVHWNFFFTMAAIRILSSSI---VLSVIFGICHQTMLKS-TGLQAWILAN-RRENLITA-NAEGLTSLMGYLTIFY--ASLAIGVVNATYILTLMTF-ATGVCLSIQM-----PCLSDSINRHSLLFFLVSNVLTGLVNLSVDAHRQ-PAFPILLAYVTVCTGLM---KIKF Canalb1 SSLKQLKEQFVSDLTGGTIEEIYAV-TSIALSSYLSRLLKKSIYDYILNVLTILA--SITLHYFIVIPSLVIYLKQFITAYRSQMLIITNLAILAVDFP-IFPRRFAKVETWGTSMMDLGVGSFVFSMGLANS-RQLIKNHLKTIKQNFI-KSVPILVLGAIRFVSVKQLDYQEHETEYGIHWNFFFTLGFLPIVLGILDPVIIGIGISIAYEVALNK-TGLLKFILSENRLESLITM-NKEGIFSFIGYLCIFI--IGQSFGLANFPYVMWVVSY-NATFLLCYDL-----STVLDSINNNGLFIFLVSNLLTGFINMSINTLET-SAVIILIGYSLTWTLLARKIYIKL Cangl S-LKERKEAFVSGLEGGSILEINVV-TSIALTSYLCNLISYN-IDFVLNWVAMLL--SFTLTTLCLIPSIGWFLKPFLTAYRSGMLILTCLAILAVDFQ-IFPRRFAKVETWGTSLMDLGVGSFVFSNGIVSS-RGLFREKIKKIFAATR-SGTTLLILGLSRLFFVKNLEYQEHVTEYGVHWNFFITLSLLPPVLVLIDPIILAMLFSTVYQLFLIKDDSLLTYLVSD-R-NTFINA-NREGLISFVGYCSIFL--WGQTIGFANMPYVLWVVCY-NTAFLLCYSL-----STLLEAMNCNGLAMFLISNVSTGLVNMCIPTIDQ-NSIVILLIYAAFLAMVSHKIFIKL Capow ISDKDRHEAFVSGHVGSNEWHIQLT-VLAAQLGPILSCARATPADFACVVLPMLL--AFTVFAEVCALAILVAISSVIAAYRAMAMVSIVFVILAVDFR-VFPRHHAKTETFGTSMMDAGVGSLAFSAGLAS--KP------NSLAAVVP-RTIPLLILGALRTLAVKATDYHEHVSEYGVHWNFFLTLAGILLLDGLFTRLLAGVFLAFAHEVLLKG--GLLDFVLAD-RSSSWIAA-NKEGVISLMGYLGLFF--LGRAHGVVNASYICWVVLY-NEVVIFIFAV-----TPLERAVNRNQLFVFLLGNLLTGLTNKLIITVDV-PANVVLLFYMLCVLGLARKVTLKA Catan2 --------------------------------------------------------------------------------------------------------------------MDLGVGIAVFAQGLVSG-LR------PSVFASAR-RSLPLWILGFLRLALTKATNYDVHVVEYGVHWNFFFTLAAVGPLIALLKSAPLALLVTVG---------SFLSWFI---------------GILSLFGYAAILL--FANSTGMANAGFVVWMVAF-NVGALGLLLL----------ALNGNGMLVFLLANVLTGLVNLSMDT----------------------GR---- Cioin -AWKAKKESFVSGLNGTSFLEVTIC-SAAYPLCVLV------VLDFLLVVFPIII--MLTVSITL---------LPFLTSFRVSVNAVTCICILAVDFN-IFPRRFAKAENFGMGVLDLGVGSFVVSNALVSAARNWNK--FSFLFFQLF-SSWPLFLFGFLRLASVKLSGYHEHVSEYGVHWNFFFTLAVVKVLATVILFIPLAVAIAASYQYLLSGNNKMTQLIFSN-REGGLLMQ-NKEGIASCLGYLSLYF--AGVQLGLANVSYCIWILSQ-STLMLFLFLM-----KCLISAINRNQLLFFLLSNLMTGAVNGLFDTQAV-SSIVIITIYAVCVTFIT-QITIKM CocheC53 KTYKQMKEAWVSGHTGSSVADVNIV-SLSMPLSILLSVIQS-FIDFLLNCGATLF--ATTLNLLLLLPAIALYVKPFITNYRGAMMVITCVAILAVDFR-VFPRRFAKVENWGTSLMDMGVGSFVFTAGVVSV-RSSLKE-SRRLTASLR-HAIPLLVLGVIRLISVKGLDYAEHVSEYGVHWNFFFTLGFLPPFAALFQSAVLSFVLAAIYEVVLDW-TSLGPYILAP-R-TDLLSK-NREGIFSFFGYLAIFL--AGQSLGLANLPYFLWVSSF-NSYQITICCASEELRSTILYAFNRNGLVVFLVANLLTGLVNMTLPTLNM-SSMAVLTAYIAVVAGVAFNVTIKL Coere1 PTSKEYKEWRVTDLEGSSMTEIHLV-LSTVALSFWCKCKTAAVFEFAVFLAPMFL--VLTICMGV---------KSYLSIYRAEMMLLTCFCILAVDFE-LFPLRFAKVETFGTSIMDLGVGSFVFSAGVVGV-KAFLPRHWHQLKAGFW-TAFPILVLGAARLLLTESVDYQKHTSEYGTHWNFFFTLGLLPIFMPLGISAVTSAALLVIYQSLYSL-TPLGEWLEAD-R-IGLVSA-NREGLFSFVGYLAIFL--LGMSLGFANAPYCFWVAGF-NTAMLWIFML-----PLIVEAVNMNSLTTFLVANILTGLVNMKIETLLC-GAMIVLTAYMILILLPAAHLRLR- Conco1 QELKKLKELHVSNNLGSSKLPILLI-ALNPVLNTLLQVLNK-IIEFLTLILPLLV--GI-IDLSIIALTAIVHLTSSILVKKSNLMLLTCICILAVDFN-IFPKYLQKVETYGTSLMDVGVGAFVFSSGVVNS-KA-----LGLLMKSLK-DSMPLWILGIVRLISVKGLEYQEHVTEYGVHWNFFFTLATLPIF------------------------TQITDLVPSP-----------------------------------ALKPWIIGI------------------------------------------------------------------------------ Conpu1 SDYKSSKEAFVSGMTGSSVVHVNLV-SAVALCSIALSAIRTRVVEWTLLVLPLLL--SMTLSLALLAPTLA-VILPAITTYRAHMMLMTALAILAVDFP-IFPRALAKCETYGVSLMDLGVGSFVFSQGVVSA-IRIVK--IPKLKAASR-KVAPIIALGLVRVALVKSTEYPEHVTEYGVHWNFFITMALLPFLEILLHYPVLGLLLAVGQEYFLSA-MELSDYVLAP-R-TNIIAA-NKEGLASLLGYLAIHI--MGLSLGMANLPYVLWITAF-NTSFILGYYLKDP--PALFEAINKNGMAVFLLANVATGVVNLSLQTMYA-SAMGVLSVYSIGVCGVA-GKKLL- Copci -DYKQAKEAFVSGMTGSSITHINLV-SLAALSSVALAVLYNQLLSWVVLVLPLLL--SMTLNLLLGLAV-A-LYLPALTTYRAHMMLMTILAILAVDFP-VFPRILAKCETYGVSLMDLGVGSFVFSQGMVSA-IPLLK--GPKLVRVVR-KAFPVILLGVARVLAVKGTEYPEHVTEYGVHWNFFITLAVVPILQTLLHPVMVGVLVGLGQQLALSQ-LGLRDYVLAP-R-DNIISQ-NKEGIISVVGYLAIHL--LGLSAGMVNLPYILWVAAY-NVTFLLAYIVRKDPSPTLLEAINRHGLSIFLLANVMTGIINLSMKTMYA-SSMSVLGAYSLVVCAVALGSHRKR Croqu1 MDYKSTKETFISGGQGCSIVDVLAI-ALTALLTYFLSLVESHTFEFFLLTVPLLL--AITLNAALALCSGV-LYQGFVTLYRAQMMLLTVLSILAVDFP-AFPRQFGKTESTGISLMDLGVGSFVFSLGIVSA-LPVLKR-WFDVWASGR-KTAPLVMLGVVRTMLVKGVEYPEHITEYGVHWNFFFTLAVLPILNTSARRLSLGLLLGSLHQLVLGY-GGLERYVLAP-R-KGLLSA-NREGLASLAGYGVIYL--FGLDTGTANAAYCAWVAAM-NVSLLLGYQL-----PRIYEAANANSLAVFLVGNLLTGLVNLSIETVYVTNSLAILEGYLAIVVGVA-RHRLRL CryneH991 GDYKSAKEAFVSDNPGASIWSINAV-SLVALATYALIALSPY-NNYLICVLPLLF--GVTFTSFLSIISLAFITLPFLTVYRAHMMLMTVICILAVDFE-VFPRWQGKCEDFGTSLMDVGVGSFVFSLGLVST-KSLSP--FTSILISLR-KSIPILVLGFIRLIMVKGSDYPEHVTEYGVHWNFFFTLALVPVLAVGIRPLVLGVIISLLHQLWLTY-Y-LQSIVFFG-R-SGIFLA-NKEGFSSLPGYLSIFL--IGLSIGLANAPYVFWVAAY-NTTFLLGYLLSSQTSPPLLDAMNKNGLAIFLAANLLTGLVNVSMKTMYA-PSMGVLMLYTLTISCVG-GRRIKI Crypa2 ASYKQLKEDFVSGLTGGPVNEIVAV-TAVLPVAALVSVLQA-VVDYLLNIGAALL--AITLIILLLAPALLVCAKPFLTFFRGSILVLTSLAILAVDFR-IFPRRFAKVETWGTSLMDVGVGAFVFSAGVVAA-RPVLKERPRRLANACR-HSVPLLVLGIVRLLSVKGLDYAEHVTEYGVHWNFFFTLAFLPPFVALFQSAALALILGVAYQVVLES-TSLKAYILAP-R-VDLLSR-NREGVFSFLGYLAIFL--TGQDTGLANLPYILGVAAL-GSLQLFAYCLKSEKESRVLRAYNRNGLAIFLLANLLTGLVNMTVPTLDV-GSIGILVAYSAVLTAVAYNINIKL Debha1 SSLKEQKELFVSNLLGGSILETYNV-TAVALSAYLSNLISSYPVDFILNCMTILL--SITLHLLILVPGILAAIKPFITAYRSHMLVITNFAILAVDFR-MFPRRFAKVETWGTSLMDLGVGSFVFSMGLASS-RAIIKQRVSLIMKNSI-KTLPVLALGLIRLVSVKTLEYQEHVTEYGVHWNFFITLGLLPIFFGIIDPVVVALVICIGYEVLMVK-TDLLSFILSDNRMESLVTM-NKEGIFSFIGYFSIFI--FGQSFGLANLSYVLWVVSY-NSTLLLGYNL-----SKILNAFNNNGLLSFLLGNLLTGLTNMTINTLGC-NTFAILVTYGLVLSIIAYGIYIKL Dekbr2 DGLKERKEAFVTGLTGGTITDVYVV-TSISAVSYLICIIKK-LLDFLLNWNNLLL--AVTLTFLILIPAVFI--KSYITIYRSQMMILTCICILAVDFP-IFPRRFAKVETWGTSLMDLGVGSFAFSMGVITA-RAYLRQHFRNLFRAIK-GSLPILGSGVFRLLSVKYFNYQEHVTEYGKYWNFFFTLGCLPPLTNLLSPIILSLTIGTTYEYILTN-RGLMRYIISP-R-VDFLSD-NKEGIFSLIGYFCICL--NGLALGMTNMLYVLWVSAY-NSTFLLCYKLKTSAKPSASTAVNNNSLVLFLVANLLTGVINMSYDTLDS-SGILVLMGYTFILSTFTSGIKLR- Dicdi DQYKNDHQNFVSGNDGSTFFETCFI-LTLMPISVLFRVVFATILEFFFIIVPFIS--AITLTPFLIVGMLITCLKGFLEEYRAFVMAATCICILAVDFQ-VFPRRLGKTETYGISLMDIGVGSVVLSGALVSN-KTSSSSSSSLMWHQVK-AQAPLMILGFVRMILTKSINYQEHVSEYGLHWNFFFTLGFVSISLAFLK-FILGVVLICVYQFLLNS-FGLTDYILHP-R-DNLISM-NKEGICSFVGYLAIYL--IGTKIGMANLGYVLAILSI-NLFNFSINIL-----SVIAKSINRNQLFIFLLGNILTGLINFSMKTIYA-PSMIIITSYTFALCLLAKNINIKF Dmel MDSRAAAESAVNQTLEEQVYDWDWWGTLVQSGESLLCILLARATEFLLVILPCIL--LVSIGLLMLVATLWFLRRPMCLSIRALTHLITAVCILAIDFG-SFYRPYRKSRQFGAKLMDTGIGLFVFTMAMVST-RHWSD-----LRRSVIYSALPLILLGLARTVSILTLSYGQDAHEYGQHLNAFFTLGFTKFLGSLVSILPLGFGLLVIHQFGLSV--GISDYVMVE-R-SSFLNA-NREGLVSLPGFVGLFL--LSIYVNTCNLGYVIWMLAIGSTTLCASFGALSGEAFTISQALNKNGLTFFLVANILTGMVNIFLRPEDR-SSVIILLVYMFLATKLV-GIRLA- Enthi EQYKIEQIEFVSDYSGSSYLLLLSMFVINIYLNYFH------LSDLFAILIPMFFS-SIVLVIILLIYLIVCYHYPVISVGRSMINLWTLIAILAVDFH-IFPRMHTKSEFYGLSLMDTGVGAIVVCSGVAAG--------FKNLISNVI-HSLPFFIIGFIRLFATSITGYQHHISEYGMHMNFFFVLGFVQILTSLIHSSIVSVVLIIGYEIILQY--DLYNYSLAD-RMSNLFAA-NREGFLSIIGYTSIQI--ASTAMGLINLTYFI---AL-MSQMMICYAI---------NGLSLNQLPLFLIANVITGVVNLLFYTLYV-PSIVIIFIYIAIVRIMAYFKSLKL Falba HDYRQAQEAWVTGHTGSSTAVALAHSLLVVVLSAVVRLAAASL----ALCWPEW---NATLALLA---------KLALSHLRAGLLLSTCIAILAVDYA-IFPRSFAKTENYGISVMDAGVGCFVF-IGAVSARWARLDQELGDLLRAVW-SAWPLLLLGFGRLLAVRSTGYQEHASEYGRHWNFFFTLGAVPALVTLATAVLAGL--LPVWQWLLTG-SAAELAITAP-EWVPWVVGQNREGLVSLAGYLAMAL--AGARAAVANPAYALWIVAA-MLLAVGALLL-----GPLARALTRNQLALFLAANVSTGLVNLTTRTLDA-SAMLAYTAWLLGLAVLLLDVTLRW Fomme1 ADYKASKEAFVSDGTGSSITHVNLV-SAVALCSIALTALQSHLLEWTVLVLPLLL--SMTLSFILLVPT-VLLFLPALTVYRAHMMLMTILAILAVDFP-VFPRSLAKCETFGVSLMDLGVGSFVFSQGVVSA-IPLLK--VPKILYVSK-KVLPLFVLGIVRVISVKGTEYPEHESEYGTHWNFFFTMALLPVLEVLLHPVLLGFLVALSHQLTLSL-TPLQNFALAS-R-TNLISG-NKEGLVSLTGYLAIHL--LGLSVGLANLPYVIWIAAF-NTSFIMFYLLLHPTSPALLEAINRNGLALFLLANVLTGLINLSMSSMYA-SSMVVLSLYSFGMCSVALALKA-- Fusgr1 ASYKQQKEDFVSNLSGGSVAEINYV-TSVAAVAILLSVLQA-AVDFLLNVGAILL--SVTLNLLLIAPAILVFTKPFLTNFRGCMLIVTCVAILAVDFR-LFPRRFAKVETWGTSLMDLGVGSFVFSAGLVAA-RPVLREKSSRLVQSLR-HSIPLLVLGFIRFLSVKGLDYAEHVTEYGVHWNFFFTLGFLPPFVAIFQSVALSLLVGVTYQVLLET-TSLKAYVLAP-R-TDLISM-NREGIFSFVGYLAIFL--AGQDTGMANLPYVLWVVAF-NTIQLLGFAVKTEKESRVMRAYNRNGLAVFLLANLLTGLVNMTVNTLDA-TTMGILVVYSAALTGVAYNISIKL Galma1 GGYKQAKEGFVSGMTGSTITHINLI-SLVALSAVSLAALRTRFSSWMILIFPMLL--AMTLNLFLLLPT-G-LILPALTTYRAHMMLMTVLAILAVDFP-VFPRELAKCETFGVSLMDLGVGSFVFSQGVVSA-IPLVK--FPKLLRVTW-KSLPIIALGLLRVLLVKGTEYPEHVTEYGVHWNFFITLAVLPVLQVLLHPLMVGSLVGVVQQIALSQ-LELREYVVAP-R-TSLVSA-NKEGIVSLLGYLSIQL--LGLSAGMVNISYILWVAAF-NVSFLLCYLLTDQNSPKLLEVVNRHGLSVFLLANVLTGLINLTMSTMYM-SALVILSLYSIVCCGAPKGAGAKG Ganpr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 IAYKKEKEDWVTGHSGGSTWEINSV-CGVLLSSYIISALSKYILEFIIIVLPSVL--ACTINALFLSLSIFV--KPFLSIYRASMMILTCISILAVDFF-VFPRRFAKVETFGTSLMDLGVGSFVFSSGIVAA-RPFLKKPKGQLFKAVK-QAFPLLLLGFIRLIMVKGVDYQEHVTEYGVHWNFFFTLGFLPIFVTLCRALIVGLFIAVFYQIALWE-FGLEDYIQAP-R-TNLISA-NKEGIFSFWGYLSIFL--FALDIGMANLSYVFWVASF-NITYLSLFQS-SYEKPNLAEAINSNGLLIFLVANLLTGFINLSIRTIYT-SAEIIIIGYMFIIISFSLGLRLKL Hisca1 QTYKERKEAFVSNLSGGTILEINAV-TLVAPAAVLLSALQS-ITDFLLNVVAILF--ATTLNILLISPSIFILLRPFLTSYRGTMMIATCTAILAVDFG-IFPRRFAKVENWGTSLMDLGVGSFVFSGGVVST-RSVLKSQPKRLLGSAR-HTIPLLVLGLVRLYSVKGLDYAEHVTEYGVHWNFFFTLAFLGPFVEIFHSLALSSLIGIGYQVVLES-TDLKKYILSP-RGPSLLSK-NREGVFSLLGYLAIFL--AGRATGLANLPYVFWVVAF-NNWQLFLFCFPSEEESRILHAFNNNGLAIFLIANLLTGTVNMGMNTLDA-DAMAVLVGYAAVLTGIAWNLKLKL Klula1 DELKHRKEAFVTGHSGSSIADLRDV-TLAGIFSNAAIYVVSNWLDFLLNWMGLLC--SVTTGILGLSAVLLFGCSATLTVYRSTMLILTSIAILAVDFP-IFPRKYAKVETWGISLMDLGVGSFVFSNGIISY-KRL----WAKIKQSLR-STVVLVVLGFIRLFSVKAVNYQEHATEYGIHWNFFFTLSLLPLAMIIFDFYVIGLIAAIIYELCLIYHPTFLDYLLAE-R-IDFISA-NREGIFSFVGYCIIYL--AGQQVGFASIGYSSMVISF-NLLILTFDQL-----PKTYRAVNGNGMLVFLISNVTTGMVNFTFNTLDS-PAMAILTVYALFLAVFA-KVPFKL Lacbi2 NDYKAAKEAFVSGMTGSSITQINLV-SLVALSSVSLSALCTRGLSWVLLVLPLLL--SMTLSLFIFIPT-A-LLLPALTTYRAHMMLMTILAILAVDFP-VFPRSLAKCETYGVSLMDLGVGSFVFSQGIISA-IPLIK--PSKLFKVTR-KSLPVIVLGLVRVLLVKGTEYPEHETEYGRHWNFFITLALVPILQVLLHPMLLGVLIAVGQQSALSH-FGLESYILAP-R-TSIISA-NKEGIVSLSGYLAIHL--LGLSAGIVNLPYILWVAAF-NTSFLLLYLVKEPISPQLLEAINKHGLVLFLFANVLTGAINLKVETMYA-SAMCILGVYSLVVCAVAEGGRP-- Lenti61 DSYKASKEAFVSGMTGSSIGHINLV-SFASL--VPLSAARTRMGEAILLVIPLLL--SVTLCLLLTAPT-V-LLLPALTTYRAHMLLLTFICILAVDFP-VFPRALAKCETFGVSLMDIGVGSFVFSQGIVSA-IPLVK--LPKVSLVLR-KCSPVLLLGLLRTISVKGTEYPEHVTEYGVHWNFFITLGLIPILQVLLHPLLLGVVVAISHQLALSM-GGLAQYILGP-R-DSVIAA-NKEGIISLTGYLAIHL--LGLSTGMANLQYVVWIAAY-NSTFLLGYLVYSPMSPPLLEAVNKNGLVLFLLANVATGLINLSMQTMYM-SAMLVLATYSFSVCAVA-HRKVWR Malgl1 SSYKRDKEEWIMGQSGSSIAYINLL-SLTPLASYALLCVNGRVADFVMLVVPLML--ACTLLSCLSLPTVVLMLWSYVTIYRAYLMMLTTFCILAVDFP-VFPRFLAKCETWGTSLMDLGVGSFAFSHGLVS---------RSSFSRLLR-RTLPLVLLGAVRVLTVKRTEYPEHVSEYGVHWNFFFTMGLVLPFIDVSQQILYSLGIALVHESVLAW-TPLGTFAINP---LSWVSL-NKEGLVSLPGYVVIAL--AGLDIALANFPYTLWCAAF-NVSLLLGFKV-----PRLFDLINRHSLILFLISNVLTGLINLLVPTMYT-SSMILLFLYMAIVCAVA------- Mellp23 MEYKSTKENFVSGGQGCSMLDVLAI-AITALFTYFISLVNGRLTEFFMLTTPLLL--AITFNVALALLSWS-VSQEFVTLYRAQMMLLTVLSILAVDFP-VFPRKFGKTEHTGVSLMDLGVGSFVFSLGIVGA-LPVLKG-WVEVWNGVR-KTVPLVLLGLIRTILVKGVDYPEHVTEYGVHWNFFFTLAILPMVGVAAHRLSLGLLLGIFHQLMLSY-AGVENYVLAP-R-HGLISA-NREGISSLAGYGVIYL--LGLDSGTANGAYCAWVAAM-NVFLLLGYEL-----PKTYEAVNRNSLAVFLGANLLTGLVNVSIETVFVTDSLLLLEAYLAVVIMVA-EYKLKI Mnele ERIRLNHPSWLSSEDS--VLNVAIT-TLIAPICLFLTFIRSKLLDCICLVVPIII--SFTLVLLILILCIC---MPYLNTYRALVNLCTIIVILAVDFSLIFPQKFHKRYTNGFSLMDTGVGSFIFSHALVAS--------LKRMQKCLI-SSSMLIVLGCGRLFVTWLTDYSVSEEEYGKHWNFFFTLALVKLLTTMIFC-IVAALVGIGYQGILSL-ADFEDWIIGSYT-GDFVHA-NRPGLFSSLGYCSLYL--FGVQVGIANLTFVIWQICH-NTVLLLSSYA---TPCCLLSAINKNQLFFFLIGNVLTGVVNLVVKTGSV-GAVATLIAYGGVVCGLTFDISTKF Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 AAYKAEKEAWVTGHTGGSMSEATLV-TAAALTTFILASIQKYLLDFSTLVVPMLL--SCTWSFATLAFAAVVKSKIFLSVYRAGMMIMTCIAILAVDFP-IFPRRFGKVEVYGTSLMDLGVGSFVFSSGVVSA-RGYLKKE--QMVIALR-TSIPLLVLGLGRYISTKGVDYQEHVTEYGMHWNFFFTLGFLPIFVTLFRSLILGTGVALVYQYFLSY-RGLEDYIQAP-R-VDVVSM-NKEGIFSFAGYLAIFL--VGVDVGMANLSYFFWVITF-NTGYILCFLLGSSKKPPLLEAVNKNGLAVFLVANVMTGLVNMTVKTLYT-PALGILTAYIAAVTGLAQGWKLKL Mucci2 EDYKLAKEAHVANCTGGSIHEINLV-CASLVSAHMLTSLV--VPEFLIYVLPVLA--CLTVTIGMATIALFILSKSYLTVYRAGTMILTCIAILAVDFQ-FFPRRFAKVETFGTSLMDVGVGSFVFSSGVVAS-RAYIYPQIKSFIASIR-SAFPILVLGFARFFLTKSVNYQEHNSEYGLHWNFFFTLGFLPPFVTTLSFLVLATVIAVGYQVAL-C-QGLQDWILAP-R-VDMISA-NKEGICSFAGYLSIFM--FGLECGMANLPYIFWVIAF-NLTLLSCLVL-SHIRPPMLDAVNINGLFTFLLANILTGTVNLSIRTLYA-NSCFINAVYMLIVTAVPFRMRIKF Mydma ADLKKAKELFILNTHGTTLIDIFST-ATLSVLCCVL------FLDLCLIVIPMVL--FFTLSVVILLISVLILLFHYISIYKANIQIATAVCILAVDFN-VFPRRFAKADVFGIGVMDCAVGSIIFSTAMTSS--------VQILIKTFK-SSIFLLALGIFRVTLIKIANYQENISEYGVHWNFFITLAFVKIFASVILYIMISFGIIIIYQTMLSS--GLASIIQNQ-R-VSFIDA-NREGICSTLGYISIYF--FGIFFGMANLSYFCFQISF-NAFLLLGFLI-----PLLYKVVNQNLLVYFLLANVMTGAINFYVQTLDQ-PSLLIIYAYMFLLNI--------- Neucr2 QSYKQLKEDFVSNLSGGSVSEIAQV-CAVAPVVSLVSVLQA-AIDFLLNVGALLL--SVTLNLLLLTVAAFVYLKPFLTNYRGNMLIVTCICILAVDFR-LFPRRFAKVETWGTSLMDMGVGSFVFSAGVVAS-RPVLKERSTRLKTSLR-HSLPLLVLGFIRLLSVKGLDYAEHVTEYGVHWNFFFTLGFLPPFVALFQSAGLALLLGVVYQVLLET-TSLKAYILGP-R-NDLLSM-NREGVFSFFGYLAIFL--AGQDTGMANLPYMLWVAAS-NAVLLLAFYLKTEKESKVLRAYNRNGLAIFLLANLFTGLVNMTVPTLDV-GTVGILVAYMGALTAVAYNVTIKL Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 PSYKARKEAFVSNLAGSTILEINAV-TLVASTSVLLSALQS-ATDFILNVLAILF--ATTLNILLVSPAVLLFLHPFLTTYRAAMMIVTCVAILAVDFR-AFPRRFAKVENWGTSLMDLGVGSFVFSAGVVSA-RAVLKGRHKRLVGSAR-HSIPLLVLGLIRLWSVKGLDYAEHVTEYGVHWNFFFTLGFLPPFVELFDSLVLALGIAVLYQVALES-TDLKGYILSP-RGPDLLSK-NREGIFSFIGYFAIFL--AGRGVGLANMPYVLWVSAF-NSVQLFLFCLEGEAESRILHAFNRGGLAVFLIANLLTGAVNLSIPTLDL-NAMGILIVYAAVLTGAAYNIKLSL Phybl2 DEYKRAQEAWVSDCTGGSTFEVITI-CFSSVASHILSSLS--WAQVLIYCLPVFA--CQTVSIGLLTASALVYNKSYLTVYRGCTMLMTCIAILAVDFP-IFPRRFAKVETFGTSLMDVGVGSFVFSSGVVAS-RAYLAGNVQSF----R-SALPILVLGGLRLVLTRGVDYQTHTSEYGLHWNFFFTLGFLPAFVTLVSFLVLALTVGALYEAVL-Q-YGLQTWILAP-R-VDLLSA-NKEGIFSFFGYLSIFL--FGLDSGLANGPYVLWVVAF-NLSLLAALVF-SQVKPSLLFAMNQNGLVTFLVANVLTGLVNLSIRTLYC-SSFLVCSIYIVAVTLFPFQIRFKL Picst3 SSLKEQKEQFVSDLLGGSVLEIYAV-TGVALTSYLARIYDVLLYDFILNCLPILV--LITLHLAIIVPILLIFVKSFITAYRAHMLIITNLAILAVDFN-VFPRRFAKVETWGTSLMDLGVGSFVFSMGLVNS-RAIIKNKFSVVKRSIV-KSVPLLVLGGARLVSVKSLEYQEHVSEYGIHWNFFITLGLLPVLLGVLDPVVVALVITIGYEIVLVN-TELLRFILSDNRLQNLITM-NKEGIFSFFGYFAIFV--FGQSFGLANLPYVLWVVSY-NATLLLGYNL-----SYLLESTNSNGLLIFLIANVSTGLVNMTINTLEC-SAFAILTVYAAGLCLLSKGIYVKL Plicr1 ESYKASKEAFVSGMTGSSIMHVNMI-SAVALSSIALGALRTRHAEWIILILPLLL--SVTLSTLLLIPT-G-VLLPALTTYRAHMMLMTVLCILAVDFP-VFPRSLAKCETFGVSLMDLGVGSFVFSQGIISA-IPLIK--LPKLLGTSR-KILPIIVLGVVRVLLVKGTEYPEHESEYGAHWNFFITLALLPLLQVFLHPFLVGALVALMQQVTLSA-LGARSFVLAP-R-ANVFSA-NKEGIVSLMGYMAIHL--LGLSAGMANMPYILWIAAF-NTLYLCGYIWYSSPSPELLAAINKNGLPIFLLANIATGLINLTIPTMYT-NAITVLALYAFGICVAA-ERRLW- Polpo EQYKLEHEEFVKNPTGSTLFETCTV-LNIIPVSLLLKVLFTTFLEFSIIVLPCIA--SVTMTIPLILLMLLTCLKRFIEEYRAFVMIATIICILAVDFK-VFPRRFSKTETFGISLMDIGVGSVVLSGAMVSN-KSRASTTKALAYHAFV-SNAPLMLLGFVRMLLTKSTNYQEHVTEYGIHWNFFFTLGFVSIVLSFLK-M-------------------------------------------------------------MTNLTYVMAILAL-NIFNLSVNLL-----SAITQAINRNQLFIFLLANIMTGLINFSIKTIYA-SSMKIIVGYTSLLVIIALNITLKL Pucgr2 TSYKEEKEGFVSNGGGCSGSDIVAI-LASLLLTHLLSLNNNHMTELTSLVVPLLA--ITTSNLCLALAA---LIQPFLTIYRAQLVLLTSISILAVDFT-IFPRKFAKTESWGISLMDSGVGSFVFSLGIISA-LPILKR-LSELWRSTR-KTVPLFLLGLIRIIFVKGVDYPEHVTEYGVHWNFFFTLSILPLTGVLTKRFLIGLLLAICHQSLLSV-VGIQEYVLRE-R-TSLISA-NREGLASIPGYMVIYV--LGLSAGLANPTYCFWIAAL-NLSLITGHSF-----PLIFQFINQNSLAIFLFANLLTGLINLSVHSIYL-DAFFLLLLYSVLITIFA-SFKLSL Punst1 DRTRAKKN--------------------------------------------------------------V---VPALTTYRAHMMLMTTLAILAVDFP-IFPRALAKCETFGVSLMDIGVGSFVFSQGVVSA-LPVLK--LPKIMASAR-KVLPILALGLIRVVLVKGVDYPEHVSEYGVHWNFFVTLAVLPVVQTALDPLSLGVLVATAHQTTLSY-LGGSHYILAP-R-IGIISA-NKEGILSLPGYLSIHL--LGLSLGMANLPYILWVAAY-NTTFILGYFASRPSRPALLDAINRNGLMIFLLANLATGLVNLTMPTMYM-SAMTVLVGYSLALSAAA-SRRIIK Rhior3 ----------------------------------MTAS-------NYIYYIPMLG-----------------LVKSYLTVYRAGLMIMTCAAILAVDFQ-FFPRRFAKVETFGTSLMDMGVGSFVFSSGVVSS-RSYMNNKLKSF----R-SGFVILLLGFARFFLTKSVDYQEHHSEYGLHWNFFFTLGFLPPVMTLLGFLVLAIIVIVIYQIVL-Y-LGLQDWVMAP-R-TGLISA-NKEGICSFFGYLSVFL--FGLQTG---LP------------------------SPMSSETSIA-----------------------------FSGVVLLLAPICPLLHLI-- Rhoto1 G-YKEDKVAFVSHATGGSVTHINLV-CATALTTYALTVAQRRILEVLILVLPLLL--ALTLNAILILLTLAWH--PFVTSYRAIMMVMTVLCILAVDFP-VFPREFAKAETWGTSLMDLGVGSFVFSLGLVSA-LPLLRSHFSSVFRSIR-KCLPLVALGIVRVVMVKGVDYPEHVTEYGVHWNFFFTLALLPVFGTALEGLVVGLAVGVVHQLALSW-TPLQHWALAS-R-TTLISQ-NKEGIVSFPGYLSIYL--LGLATGAANLPYVLWTVAF-NTSFIFAYLMSSPSSPAIFHAINQNGLVVFLVANLLTGLINVLLPTMYM-RAVVVLVGYAAVVVGVA-GRRVKV Rozal11 -------------------------------------MLTT---------------------------------KPFITAYRAMMMLLTCICILAVDFK-IFPRRLAKTELYGTSLMDLGVGSVVFSGGVVSA-KSIVQDK---IKRGAT-KSIPVLVLGLIRMLSVKGLDYQEHVSEYGVHWNFFFTLGFLQIFVAIVQAFKFSIVLMGVLEVCLRR----RGNVLSDDR-SDIFLM-NKEGITSLFGYLCIYL--TACKLG-GSFDYFL---------------------CSILGAVNRHQLLTFLLANVLTGLINMNMQTLLA-SAIAVVSVYMIIVCWIA-KVDEKL Sacce1 T-LKQRKEDFVTGLNGGSITEINAV-TSIALVTYISNLLKN-IIDFALNWVALLL--SITLNTLILLPCLLAFIKPYITAYRGGMLILTAIAILAVDFP-IFPRRFAKVETWGTSLMDLGVGSFVFSNGIVSS-RALLKN-LKNAFNALK-SGGTLLFLGLLRLFFVKNLEYQEHVTEYGVHWNFFITLSLLPLVLTFIDPVSIAIFISCIYEWLLLKDDRTLNFLIAD-R-NCFFSA-NREGIFSFLGYCSIFL--WGQNTGFANLPYTLWVITY-NLLFLTGYCL-----AECLESINSNGLFLFLLANVSTGLVNMSMVTIDS-SSFLVLLAYCSFIAVISKRIFIKL Salro -------------------MVLGIVASLSTLVALCLTRKARAFRTFAIAIDAALLS-ASTAPALILILSAIVVRPPWLTAFRAAMMFSTCVIILAVDLP-IFPPTSAKSVSYGFSLMDLGVGAMAFAAGFVVA------------------AAAVLALLGAMRLISVKATAYHEEVVEYGVHWNFFFTLAALLVLHRAFRALLAVSAVAYANHHLLYH--GWEEYIFAP-R-TDLLSQ-NREGLFGLLGFACIFE--IAHRAGLVNLPYVALVLAI-CFLILLIFAH-----SPVLRALNQRGLEAFLVANLFTGACNMALPTATL-SSVLLLTAHGLVVIATSPRARLKS Schco3 ----------------------------------------------------------MTLIVGLGAAA-A-GLLPALSTFRAHMLLMTILAILAVDFP-VFPRELAKCETYGVSLMDVGVGSFVFAAGIVSA-LPILK--PPKVLSVAR-KAAPIIALGLVRVALVKGTEYPEHVTEYGVHWNFFITLAVVPVLQVLLHPVWLAVLVGMTQQALLTV-GGLDRYVLAP-R-ATLLSQ-NKEGIVSLLGYLSLHL--LGLATGMVNLPYILWVAAY-NTTALLGYFAYDPTSPALLEAINKNGLALFLLANLLTGAINLTTQTMYA-SAMVILTAYAGVVCWVA-GRRVVK Schpo1 MSYKLEKEAFVSNLTGSSSIETCGL-LLIGIACNVLVNMTARLVEFFIFCLIPLF--VI-FTLCIFLPSFVLHVIAGVTFYRSQMMLVTVTCILAVDFT-LFPRRYAKVETWGTSLMDLGVGSFMFSSGTVAGRKNDIKK--NAFKNVLW-NSFILLILGFARMFLTKSINYQEHVSEYGMHWNFFFTLGFMALGVFFFRRSNLATFITLLHHCLLVL-TPFQKWALAP-R-TNILAQ-NREGIASLPGYIAIYF--YGMYTGLANTPYVANVAFI-NMFFLTIYIL-----PKLLEDANNNGLLVFLIANVLTGVVNLSFDTLHS-SGLTIMTMYLFIICYMAHGIRFRL Sorma QSYKQLKEEFVSNLSGGSVSEIAQV-CAVAPVVSLVSVLQA-AIDFLLNVGALLL--SVTLSLLLLTTAAFVYIKPFLTNYRGNMLIVTCICILAVDFR-LFPRRFAKVETWGTSLMDMGVGSFVFSAGVVAS-RPLLKERSTRLKTSLR-HSLPLLVLGFIRLLSVKGLDYAEHVTEYGVHWNFFFTLGFLPPFVALFQSAGLALLLGVVYQVLLET-TSLKAYILGP-R-TDLLSM-NREGIFSFFGYLAIFL--AGQDTGMANLPYMLWVAAS-NAVLLLAFYLKTEKESKVLRAYNRNGLAVFLLANLLTGLVNMTVPTLDV-GTVGILVGYMGVVTAVAYNITIKL Sphar AEYRELQIAAVSHNNGTTYAE---V-QLQAIATYYVSVFRSRISEVGALLIGLIV--SLTMPLWIAVNIVFVLLKSFVTVYRSTMLVVVLFCILAVDFN-IFERRFTKTETFGVSTMDTGVGAFILNNSIVTA--------KGGLLRILK-SSLPLVVLGLLRLLTVKSLDYQEHVSEYGVHWNFFFTLFFTGIVSNTVRALMFGLAIATAYQWVLDN-YGGEQYILHP-R-SSIIHA-NKEGVCSIVGYTALYL--MGCGIGMMNLPYIIWAFIT-TTSVLLLVFF-----SKLMLAINRNQLFLFLLGNLLTGLVNQTTRTNCA-SAYTILIAYICILMGLALKLTLKL Spipu1 EATRRAKEEHVTGHNGTSVLELQQV-LTVTLLSYALKAVTQTSCEFATLVLPFLL--SVTLAALLLATVFVSCLKSIAQFHRGCLQVVTIICILAVDFR-VFPRRFAKTETFGTSLMDLGVGLFIFSGGVV-A-GPRLKTTIKLC--------TPVMILGVARMILTKGVNYQEHVTEYGVHWNFFMTLALIPLVITILQLLTLAVVISVAYTILLQN-MGLERYIMAP-R-DNIFSM-NREGICSFFGYLAIFL--LAADIGLANISYVLWVSLS-GVYHVSGCAL-----PLLYKAINRNQLAIFLVGNLLTGLVNLSVNTLEV-SAYAILTLYIFIVGGVALNLTLKL Sporo1 G-YKEDKEEFVSGSTGGSVTRINLV-CSTALTTYVLTVVNARSIEFGILIFPLLC--ALTFNVVVSTLAIATS--PFVTSYRAIMMVMTVICILAVDFP-VFPREFAKAETWGTSLMDLGVGSFVFSLGVVSS-LPLLRRTFGSVLSSAR-KALPIIALGFVRVIMVKGVEYPEHVSEYGVHWNFFFTMALIPVFGNF---------------LALQL-TSLQEWALAP-R-TNLISA-NKEGLVSFPGYLAVHL--LGLASGLANLPYVLWIAAF-NTSFLFLYLVFSPRSPVIFEAINRNGLVVFLVANLLTGLINVSIESMYT-SATLILLSYCSIIVGTA-GRTLKL Stehi1 --MKSS---------------------------IALSALRSRLTEFCLLIVPLIL--STTLSSILLIPA-VLVLLPALSTYRAHMMLLTIICILAVDFP-VFPRELAKCETYGVSLMDIGVGSFVFSQGLVSA-APLLK--LPKLVRTTR-KCAPIILLGLVRVLLVKGTEYPEHVTEYGVHWNFFLTLATIPILQILLHPFLLGVIVAVADQVLLSS--GLTNYVLAP-R-QGIISA-NKEGIVSLTGYLAIHL--LGLSTGMANLPYVAWVAAY-NTSFILGYLLYSPTSPTLLEAINRNGLAVFLLANLATGLVNMTMSTMYA-SAMAVLLGYSGLVCSVA-GRRLWV Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --WREAREAHVAGLSGSPLWVVCAVSLVLPVAAA----ASMA--------WP-----------VA---------VAALSTYRAMVMVATAVAILAVDFD-AFPRMYAKTEVHGVSLMDVGVGSFVFSKGMVTP-------E----------NLAPLLVMANIRLVVHKAIGYQEHVSEYGVHLSFYHTLCGI---LVVAWTLALGLAAAAAYQLALTG-YALQAYLLVS-RTTSFAAA-NREGLYSLGGYAGLLLLGMGVGAGLANGPYIAWIVAH-NV----SLLA-----SPAVAFVNGHQLLFFILANLGTGIVNLSIDTLSF-GALIVVSCYILAVPLVVPGSGQKK Treme1 SDYKTVKEAFVSNNPGQNVWTINSI-SLVALSSYALASLVGR-VDYLTTVLPLLL--SITFN--LAILSLVFLILPFLSVYRAHMMIMTVHCILAVDFN-IFPRSQGKCEDFGTSLMDVGVGSFVFSLGLVSS-RSFLPHSLSQVLRAMK-KSAPVLLLGLVRVIMVKGSDYPEHVTEYGVHWNFFFTLGLMPIFGILLRPLILGLLIATVHQLSLHY-AGIQTWVLPL-R-NNLLSQ-NKEGLVSLPGYLSIYL--LGLAAGMANLSYVLWISAY-NTSFLLGYLLFSETRPGLLEAINRNGLIIFLVANLLTGLINLSMETIYV-KALIVLVGYSAGICLIA-GLRLRL Trire2 ASYKQRKEDFVSNLSGGSVSEISYV-TAVAPAAVLLSVLQA-VVDFSLTVGTFLL--ATTLNLLLLAPALLIWLKPFLTTYRGYMMITTCVAILAVDFR-LFPRRFAKVETWGTSLMDMGVGSFVFSAGIVAA-RPVLKERATRLLQSIR-HSIPLLVLGFVRLLSVKGLEYAEHVSEYGVHWNFFFTLGFLPPFVAIFQSIALALLLVGTYQALLEY-TNLKAYILAP-R-VDIISM-NREGIFSFIGYLAIFL--AGQDLGLANLPYVLWVAAF-NCWQILAFCVRSEKESYVLKAYNRNGLAVFLIANLLTGLVNMTIPTLDA-TAMGILLAYTATVTGVAYDISIKL Umbra1 DEYRVEQEKWVSNCTGGSLTEINQV-SASLACSYLFVCLQR-LAQFMVLILPILA--CQTVNLSLLTASSA-LYKNFLSVYRATMMVMTCIAILAVDFP-IFPRRFAKVETFGTSMMDLGVGAFVFSSGVVSG-RTYANTAIPNFIRSLR-ASFPLLALGFIRLAATKGVNYQEHNSEYGLHWNFFFTLGFLPPFTALAASLVLGLSTAIVYQVAL-A-RGLQEWALAP-R-VDLISA-NKEGICSFFGYFSIFL--FGLDAGIANLPYVLWVVTF-NFGFILIFTM-SQSSPKLFESININGLVVFLVANLLTGLVNMSMRTLYA-SSFIVCAMYMFIVTKFAFNIRIKL Ustma22 SSYKQLKEAWIAHQTGSSIHVINLL-GLVMLLTYAISVLRAKQLEFLILVAPAVC--AHTTNCALLVLL-VLLIQPFLTVYRAHMMLVTIISILAVDFS-VFPRFLSKCESWGTSWMDMGVGSFVFSLGIISA-LPFLK--RQQLVSDFR-KALPLVALGSIRIIMVKGVEYPEHVSEYGVHWNFFITLSMLPFAATLSRPFVLGILLSVLHQVLLNC-TSWQTWAIVQ-R-TTLLAQ-NKEGLTSMVGYLAIFY--IGLDLGLANLPYVFWVAAF-NTSFLLCYVMQEQQEALILQDLNRHSLTVFLAANLLTGLVNLTLKTMYI-RAVVILLAYTGICCGLARNIRLKL Walse1 MDYNQVKDQFMSDNAGEAVKTINNL-SFIAINSFILSILIKRITSSLVLFTGIFL--ATTLNVILATTSIITLIKSYITNYRSYLLYLTLLSILAVDFP-IFPRKLAKTESFGTSFMDLGVGSFTFALGVVDAKYHILKSY------NMR-KVLPLIALAIIRLIAVSLSDYPQHSSEYGTHWNFFCTLAMLPLLTKPLTIIWMAVLIGGSFQVLLSC-TSLQEWTLAP-R-DDVLSH-NKEGIVSMIGYLCIYL--FGLDIGMANLPYILWTVAF-NTSFLTLFLL-----PGILQAINNNGLALFLIANVFTGIINLSIETIYS-SSTMILAVYLSTLLYVA-SSRLLR Zygro1 VDLRERKEQFVTGLQGGSIEEINTV-TAVAPLVYFCNLLSSS-VDFALNWVCPLL--CITLYTLISVPCISIWFKPFITAYRSGMLVLTVLAILAVDFP-VFPRRFAKVETWGTSLMDLGVGSFVFSNGLVSA-RALLKERAKKSLIAVR-SMVTLLIIGLIRLCFVKNLEYQEHVTEYGVHWNFFITLSLLPPVLVFLEPIAIATATSIIYEIILARNEKVLNFLVAP-R-TDFFSA-NREGIVSFTGYCSIFL--WGQTTGFANLPYVIWVVGV-NQGGLAVYCL-----PTILEALNCNGLLMFLLSNVTTGLINMSMVTIDA-SSVITLLLYSSFLTAAAKKIFIKI [Cluster1886.fasta_al_trimmed; alignment length = 254] Allma1 ---DYLA-SKPK---------KPKKPKSAAPS---II-DEDMSYRFSTLRT--RGRSTSRS--RHDSDS-----EDD-RGP--EPDDDGG-------RPRGGSDTG------TVYRD-KMGRRVRDA--ETKEREREEKKRRDYEWGLGKVQRDQARERSRAAAEGPFA---RTADDV-DLNRELRDRDRWGDPAAPTFQGAW-PSNRYNIPPGF-RWDGVDRSNGFEAKLLMGANEKAVFEEKAYRWRSE-DM Ashgo11 SLNSYLTE------------PKRAA-KSRNGSNVSIT-DSA-----IKAKA--KRFKNLETNE-----------SE-------MSSGAHASAEQVAEKKQREAQRE------TVFRD-SSGAQIMR---DRERADERFQQNKSREMNMGDIQLHQLRNPDWR-PARCEG----------------EQIRR-DDPAAKLYNKAW-PENRFQIAPGW-RWDGVDRSNGFEQKWFAKQGELAERKAQQMAAQQDY-- Aspfu1 SLAEYLAKDRPKK--------KRKKTKTVDT-GLIIA-DDDGPS-LAEFRR--AKWRTVGG-----DERDAADAGDD-EAPAVMESGARATAEQTAAERRKKAEAARERPA-TIYRD-ASGRIIAEA--RRAEQEKREKEEAAKEALMGDVQRAEREARRQQIQEARAMPLARTIEDD-ALNEELKAQQRWNDPAAPLYKGAF-QPNRYGIRPGH-RWDGVDRGNGFEKEWFAARNKKGRLEALDYQWQMD-E- Aurde31 -MKAYLAESGPKADAILARA-KKKKRKVAAGA---VR-DDD-AV-VRSFKK--RRWTTVSAPA---KEEP-PE---D-EQPLVAHRP-RGTAAQFRAPAA------QATEEETVYRD-ASGKKIAAA--ARAKREQEELEARKMEWGKGIVQREEQERIRQEMERDKHRGHARYADDD-ELNASQKDTMRWNDPAAPEYTGPPPPPNRFGIKPGY-RWDGVDRSNGFEKKFFQRQNERRRVKDEAYSWSVD-DM Batde5 SLKAYLEKDAPSSSKLQAINKKKSKKSSKLLA---VI-DED-PM-VKTPES--SGWVTVQEVKKQRRPSP-PPS-SDNEDKAIMSDGTRATGDAIRQEQEDRKRQASELSEKTIYRD-KLGKKVAKM--LAERRRKEAEEEARMQWGKGLVQQEEQAELAKRMLEEQNAPLAVYVDDK-QLNDQQMARDRWGDPMAKVYKGPTPAPNRYGIAPGY-RWDGVDRSNGFEVKYFQQKHSRSIIGEAAYKWSTE-DM Botbo1 -MKEYLASSGPKADAILSRSKKKKKRKIGAGESSYIR-DED-VV-VRSFKK--RGWTTIRA-----PTPP-PPP-AD-EDPLVQDAAPMTRSSQLRKKLG--KAKKEVVPTETVYRD-TSGRKIAEA--ARKKREWEEKQAEKMEWGKGLVQREEKERQRLEAEKEKSRPMARFVDDA-ELNEDQKAQDRWNDPAAPEYHGPPPPPNRFGIKPGY-RWDGVDRSNGFEKKYFQRINERKRRDLEAYEWRVD-DM Botci1 SLSSYLAKSTSKD--------KKRKRKT----GLIIA-DDDTPM-ISEFRK--SKWKTVGV------DTAEADRHAD-EEPTI-----RGTRDEAAAEKKKRIEAAARESGSTVYRD-ATGRRISEA--KKEMDEKARKELEEKEAQKGDIQLLAKAKRREELDEAKFMTVARGVDDV-EMNEELKEVERWNDPAMPLYKGSA-APNRYGIRPGH-RWDGVDRGNGWEAERFKGENRRVRNKDLDFQWQMD-T- Caeel SKADYL-KSGDIE--------KKKKKKNKDKN-LRLI-EEDAPKVINSPPR-GK---PSRKRNRHDSDNS-PPRDSDNSPPRNTLEGKRSSARDLKEDKLRAKNSKEEMDTSTVYRQ-KQTKKK-DQ--AKKERETEELKEKYKSWNKGVAQIEDRRAQLEEMARVAAEPMARARDDD-AMNAHLKEVLHAADPMAPSYHGHF-VPNRFGIAPGY-RWDGVDRSNGFEGKLAKTENTKTANQSEYYK-SIA-EY Canalb1 KRADYLS-------------KPKKKKHKKKSSNIVV-ETPKAPVKLKGFKR---------------------------------------TTNNTTTPPSSLSSSSSVIKPNTIYRD-SSGRIIEDLQ-QQKLHEEQLKQFTEIKTSKQDQINQEQEIFKVKNGH----------VDN-Q----------FEDPMTFVYNKGINIPNRFNIPAGY-FWDGIDRSNGFEQMYLRKQTEYNYDKIDTYEIDIGDD- Cangl SLHDYLLKSDRKK-------SKKVDSKSTAQK---VN-SNA--------------WLSHGVNN-----------DNL------IEPPSRTPKTH------------------TVFRN-AQGHKILD-------SDRNSQEERIRILNMGEIQLAGL-DGVSTISSKYTA----------------E--IRDNDPATKLYAGTA-TENRFGILPGN-KWDGVDRSNGYEKKWFKRQGELAESKIQEFTNSEDY-- Capow SKLDYL-KSGPAASSSSSSSKHKKSSKHRSSSGDEFSDDDDAPAIVPDRRR--RQERTVQAHARHDSSSPPPPHQRDLSPPRRSPSPIRAPRRRVRHPPRRVQHADSSCSSSTVYRDKATGKRILAQ--REKEAKQAEAIERRLAWGKGAVQKQQAIERREEELAQMSKPLARYAGDA-DLEAHLRAQDREGDPMAPKYRGPPPPPNRFNIPPGY-RWDGVDRSNGFERRIVSVANSKVIREQQAYAWVAN-DD Catan2 SKADYLA-D-PK---------KKK--KKSSKS---VI-DQDPQVTISSFSS--SGVNT-----RHDSDSD----DDD-DGPPR--DDRGG-------PPR--DDPA------TVHRD-ARGRKVQEA--AAAEQAQVDKMNKDKLFMMGRVQLEQMREKRRQLLEGREASGSAAAASV-D---PLKDRMRWGDPGAPQYEGGW-APNRFMIPPGF-RWDGIDRSNGFERKLLMRQNERAADEEAKYKWRSE-DM Cioin SKEEYL-KAGEKP-------KKKRKKKVKTIQGFKIV-DDD----VASVKK--KRRKKVNESDDSDSDIDVPRNDSDLDLPRNKKKGMIGSVTDLRKEERKKQESEDKLATEAVYREKGTGKRIKEK--DEKAEKRRQKEEKYSRWGGGVKQAELKASAVADTIHESNKPLARYNDDE-DLETMRRAEMRAEDPMAPKYRGPAPAPNRFNIMPGY-RWDGLDRSNGFEKKYYENISNKQALKDEFYKWSVG-DM CocheC53 GLADYLAKSEKKS--------KKRKRKNKDA-GLIIE-DDDAPM-I-TLKK--SKWTAVG---QLAADAAAADAAED-EAPEMTASGTKATAAEVEAEEKRQAEKIEMGGAATIYRD-ASGRIIAEA--RKKAEEKREKERAAR----GDVQNAEAERRKQQLQDAKTMTVARYADDA-ELNDELKERDHWNDPAMPLYKGPF-QPNRYNIRPGH-RWDGIDRSNGFEKQWFDSRNRKANIEKLEYQWQMD-E- Coere1 ---------------------------------------------------------------------------------------MRYTAASIKEDRVHERHLRRDASSDTVYRDPKSGKEIQER--EKQERREQLR-EQHSEWNKGLVQQRAKDEELRLLENMR-----RSDTVA-LDTAKLRAKQHWDDPARPEYKGYA-PPNRFGIRPGY-RWDGVDRSNGFEKQLFEAKASSSSRRAQDYAYSVA-DM Conco1 -DKKYLLSSSLKP-------SKKKKSKNNKRA---II-DEDGAITVPKFKS--KKWTKIQGES------------SDEEQAQE-------SGDKFSQRSKEKSIKKSKVSNETVYRD-KFGKKIKKS--EAIELAQKMNIENQKQFNRGVAQREMEQQRYLELMDQKNQSMTVYKDDK-QLNETLRTQSRWEDPSAPQYSGPY-PSNRFNIAPGY-RWDGVDRSNGFEKEIIKAQYARNNLKSEAYAWGAE-DM Conpu1 -MKTYLAESGPKADAILART-KKKKRKVEDPSSAMLV-DDD-AT-IRSFKK--RRWQTVREGEPPKEETP-PPP-ED-EKPQVQEQPFRGTADKLRKPKA--KAPSEGMTQETVYRD-ASGRKIAEA--ARKKREREEKDAEKMEWGKGVVQREEKDKARRQMEKNRTGPFARTVEDK-DMNEEMKAQDRWADPAAPQYTGPPPPPNRFGIKPGY-RWDGVDRSNGFEKKLFQHQNEQRRKTAASYEWSVD-DM Copci -LKAYLAASGPKADVILAKT-KKKKRKKDSSN---IV-DED-AV-VRGFKK--RKWVTVQEGEQHEEEVT-PP---D-EQPMVT--PFTGSAKDLKKPQN--AVSQEEYTAETVYRD-SSGKKIAEA--ARLKREREEQEAKKMEWGRGLVQRDEAEKRREELEKNKSRPFARTIDDK-DLNEEMKQKELWNDPAAPEYTGPTPPPNRFGIKPGY-RWDGVDRSNGFEKKFFQAQNARKRRGAEAHAWGRP-WL Croqu1 GLQAYLASSGPKADAILTSLRRKRKKK-HRQDGFIIK-DAD-PV-VASFKA--KSWTVIKPSGQESEEIE-TIA-ED-EQPQITEQTIKGTADEIKAKTKQAK---QNTQDDTVYRD-SSGRKIAEE--KRRKARELEKSMRKMEWGKGLVQRDDKKATADELSKIAAQPFARTIDDR-EMNEELKDVRRWNDPAAPKYNGPPPPPNRYSIQPGF-RWDGVDRSNGFEKKLFATGNEQKRNKAEAYSYSVD-DM CryneH991 -LKAYLAASGPKADAILARSKKKRKKQHKNEDGLMLR-DEDAPV-IATFRA--SKWATVANKSQAEPSSP-QD-KPDIKEPDIQMTKRRGTAAQLREERELAEQRS--AEGETVHRD-VTGRIIEEE--KRKEEEERRKEAERKEWTKGMVQRRDREEKRRLEKKMAEADVGRSKDDV-RMNKEMKEEERWNDPAAPKYEGPW-APNRFGIAPGF-RWDGVDRSNGFEKKYFQAQNTRARREYEHNQWSVE-DM Crypa2 DLSSYLAT-KPT---------KKRKRKHDKS-GLLIQ-DDDSPV-TKEFRK--TTWKTVG----DDAEAAAADAAED-DDPTVMADGTHASAAAVTAERRQKEEREEAERRATYYRD-ATGRRVAEA--RRAALEAEEKERMKEEMLKGEVQLEEARKRKEVLEDARGMAVARTADDE-EMNRELKEQRRWNDPMAPVYKGPA-PPNRYGIRPGY-RWDGVDRSNGFEAERFKAINRRERNKGLDYAWQMD-E- Debha1 SRADYLS-------------DKKKKKKLKDKKNVVV-----TPVPVKGFKR---------------------------------------VSPETQLQDS--------I---TVYRD-KSGNIVKQMQ-HEKEQEQIRKRQLEQSINQGDLQKIEDAEVAAKLDQNK--SFLVSTRDS-EYNELMKSKQRFDDPLQMYYNKGVSPQNRFNIRAGF-FWDGIDRSNGFEDLIVRKRNEVSYTKRETYDLDMDDDL Dekbr2 -LGDYLAKSIGKE-------KKSKKRKHRGEY------EVDAKVVV---KK--KKWRVVGTEE---------------VEPKI-EDGTFATREEAEKKLKDEKSRKKELENATVYRD-LTGRKSSAE--ERAKKDKIEKRKESEKINRSETEVVRKLEELAKLDKVKHEGLNVYENDE-KVNEVEKRETKSDDPALKLYKNGF-PANRFNIRPGW-RWDGVDRSNGFEKRWFEKQAEIKDGKQMKYAQQ----- Dicdi -MNEYL-KSNDESNR-----NKEKKKKKKKVL---IV-DIDKPL-IDQFNF--KPWITIEPPTNYDDLSP-PRNNNDLSPPRN---------EEEEENKKHKEQKELREQQRTVYRDKITGKKVMDL--EKKRLEEQIELEKDMEWGIGKVKKKKEEEERERIQRDINKPLSRYIDDE-DLNSEQIDKDRWGDPMAPEYKGP-YPSNRFNIKPGY-RWDGIDRSNGFEKEFISKQSRNQNLAEESYYWSVE-DM Dmel DQKEYL-KSGDKE--------KKKKKKEKKHKKVKII-DDDSPVRIESPQR-GRRQSPVRKRRRSNSDQS-PPRDSDQSPPRKTLDGKKADAKSLKKDERRRQEHEEKMSSEVQVR---STRRKAEQ--GRKEEHKKEL---YDRWGKGLKQIEDHKSRLEEMVHEASKPVARYANDE-DLDRHLREQEHADDPMLPKYEGSF-PENRFGIRPGY-RWDGVDRSNGYEQRWFDKQNERRAVQDEAYKYSVE-DM Enthi DISEYYAGSFDAAKALF---DIQKNNRIDLKQHFYVK-NQD----I--FKKC--------------------------------------QIEQVHQ---------------AINNK-LTKERICKE--CHKEQEDKLNYQEYMSCA----------------SKAKQKPFKTREDER-D-----REKQRFGDPMRPKYQGKF-PQNRFGIAPDY-KWDGIDRGNGFEMKYFAQVNKKIIQKRKVVDW------ Falba -----------------------------------------------------RVALSMEDYLETDGRAP-PPA-----PP-------------------------------TVFRDKVTGKRI-EA--EKAKQRRAEELEKRSRWGRGIAQEREQMEREKYAESFKEKPFAVYADDE-ELNVRQKMKSRWGDPLTPRYAGPPAPPNRYDIHPGY-RWDGVDRSNGFEKRLIADRATGAARMARAHASHMD-EL Fomme1 --------SGPKADAILSRVKKKKKRKTATTSVNLIV-DDD-AV-VRSFKK--RRWATVREG-KREDASP-PP---D-EKPQV---PFAGNAADLKKPGQDASAGKIAREQETVYRD-ATGRKIAEA--ARKKREREEKEAQKMEWGKGVVQREDAAKRAEQLEKEKKRDLAVYADDR-ELNEEQKSTMRWNDPAAPEYTGPPPPPNRFGIKPGY-RWDGVDRSNGFEKKFFQKQNERRRRGLESYQWSVD-EM Fusgr1 DLSAYLAS-KPT---------KKRKRKRGAE-GLLIT-DDDAPV-TSEFRK--TKWKSLT----KDDSAAAADAEDE-DMPIVMSDGTHASAATVSAKRRQKEEREEKHRKSTVYRD-ATGRRIAEA--RRVAAEAEEKERLAKEALKGDVQLEEARKRREKLQDAKLMSFARTVDDE-EMNQEMKEQDRWNDPMMPVYAGAA-PPNRYGIKPGY-RWDGVDRGNGFEAERFKAINRRERNKGLDYSWQMD-E- Galma1 -LKTYLAESGPKADAILSKT-KKKKRKAKDVT---IR-DDD-AV-IRGFKK--RKWITVQEG--VKEESP-PPA-VD-EQPMVT--PFTGNAQQLKKPQN--NVGAEKMSEETVYRD-ASGKKIADA--ARLKRLKEEKEAQKMEWGKGLVQKEEAEKRRKELEKHRNTAFARHADDK-ELNDEQKAKDLWNDPAAPEYTGPAPPPNRFGIKPGY-RWDGVDRGNGFEKKLFESKNARKRRGAESYQWSVD-DM Ganpr1 SLQAYLAKSGPPSSK-----SSKRKSKPK------IV-DEDAPV-VEEAKK--TAWKRVGGGDRHDSDSE-GDRDSDSEGEQVMADGTSARAADLARAARRKEEDSRALDSRTVYRD-KSGRKVAEE--LERQRKEEAEMERQMQWGRGVAQLREAEERRERARGGAG-PLARYANDR-DMNEDMKSVDRWGDPMAPLYKGPPPPPNRFGILPGY-RWDGVDRSNGFEGEFFKRKNQNVALKEEAYKWSAE-DM Gloin1 -LNVYLAK---------AKSTKKKKKKIKSTP--IID-EEDAPI-VESQQS--SKWKPIVED-------------GD-EAPQITSSGLDVSSDKVRKERAKRDEKDNKMDPSTIYRD-NKGTKIAEE------RRKIEEEEKLLKWGK--------EEEIRREEELLNKPLAIYKDDK-DLNEELKAKERWNDPAEPRYQGPPAPPNRFNIQPGF-RWDGIDRSNGFERQYFEKQNARATLANEAYKWSVE-DM Hisca1 SLAAYLAKDRPKK--------KRKKNKHSDQDGLIIA-DDDSPYTIAEFRK--SKWKTVGG------EQAAADAESE-EKPVIMESGARATAAETEAQRKRERESLKKSSKATIYRD-ASGRIIAEA--RRA------AEAAAKDALTGDVQRREREARREAVREAKYMPLARTAEDE-EMNAELKARVRWNDPAAKVYTGPA-APNRYGIRPGH-RWDGVDRGNGFERQWFEARNKVKMREGLEYAWAMD-E- Klula1 SLNDFLAKKHGKE-------TKKSKDKSSHRKNIDII-DKA-----NKTGK--S-WKNLETEK-----------DVD------MSSGAFATAEEMEKEKEKLSMQK------TVYRD-EKGKVILK---LREKANKVRKEEELKIRNIGEVQISKL-------DRKTEK----------------SALLSTEDPLNRLYEKNF-PENRFGIVPGY-RWDGVDRSNGFETKWFAKSHDIADQKIKEQTTNREF-- Lacbi2 -LKAYLAESGPKADAILSRT-KKKKRKVD--S---IR-DED-AV-IRGFKK--RKWVTLQQGTAIKEESP-PPA-AD-EQPQVT--PFVGSAAQLKKPQN--QMAKEDLTVDTIYRD-ATGKKIAEA--ARLKREREEKEAQKMEWGKGLVQREEQEKRRLELERQRGKAFARHADDK-DLNEELKAKELWNDPAAPQYSGPPPPPNRFGIKPGY-RWDGVDRGNGFEKKVFQSANAKKRLGAESYQWSAE-DM Lenti61 -LKAYLAESGPKADAILSKV-KKKKRKATAAS--LIK-DDD-AV-IRRFKK--RQWQTVREGE---SQTP-PPA-ED-EQPQVEEEPFKGTSAQLKKPKASKQDPKAEEEAATVYRD-SSGRKVAEA--ARLKREREEKEAKKMEWGKGLVQRQDAEKRRKEEESMRSRAFARTVDDK-ELNEDLKAQERWNDPAAPEYTGPPPPPNRFGIKPGY-RWDGVDRSNGFEKKYFQRQNDRRRRGAESYEWSVD-DM Malgl1 ---------------------------------MVIR-DEE----VESLRV--PQWTAVRPPSRVLDVDPNSSSASD-DRATVSEARPQASREQLRAEARKAAEKAQGGVTETVYRD-ALGRRIAQW--RAEEDSRKRKAAERAQWNRGLVQRRQEAEQRADLAQISTERVARYADDA-RWNASRREQMHWDDPARPEYEGPVPPPNRYGIRPGF-RWDGVDRSNGFERKFLMSINQAQRSKAEGYAQAIC-SL Mellp23 -LKAYLASSGPKAEAILSSVRKKRKKKTHDPSGLILK-DED-PV-IAKFKG--KSWTVIKPS-EETNE-E-NIA-ED-EQPQIT-TGVTGTADQIKSKSQKMKQKIRAAEEDTVYRD-SSGKKIAEE--KRRQAKDLEKAMRKMEWGKGLVQRDGKKADADELSKIAAQPFARTINDQ-EMNQEMKGVQRWNDPAAPKYNGPPPPPNRYGIPPGY-RWDGVDRSNGFEKKLFATGNDKKRTKAEAYSYSVD-DM Mnele ---EEIFRESAQA--------RKKARNARHSTNMTII-DNEAPQFLSKWKKA---FTTVGFSNDSDSDNS-PPRDSDASPPRKESPERKGSANQLLEAKMKEFAEKREMEGEPVRRD-KQGNKIAKE--SAENEEERIKLEKFMMYSKGLVQHKEAAAKKADNQYEMSKPMARYNDDQ-DLNTLLKQKGRQDDPMNGDYSGPPAPPNRFGILPGP-KWDGVDRSNGYEKLLFMKQAEKLAMKQETYKYSTAYDL Monbr SLAAYLAASGKEPDE-----RQRRKKKVKRAKGLRIR-DAD-PVLVLTINE--QQASTADASPRHDSPDASPPRSPDASPPRRRRAANTSNAAALRQELRAAAEQRDALGDSTVHRD-KSGRRLLRK--REMEQKREELEQEQMEWGRGLKQTRDAQDRRAEIEHEMSKPLARSRNDE-DLNKMQRDEIRAEDPMAPRYRGPPAPPNRFGIEPGH-RWDGRDRSNGFEQRWFQTRARGAAVGKDAYKWSVE-DM Morel2 -TQDYL-KSKP---ASLDE-HKKRKLKKKKTSNFAIH-DEDFPV-VKAPEY--KSWATVREGELKRNVVP----NED-ERPSISLSPYAATAEQVKRMRQKEKEQSMRASNSTIYRD-ARGRKVLEA--AEAARKEIEKQERQMEWGKGLVQREAEEEKKRREQEEKLKPLARYKDDK-DLNEELKERDRWNDPAAPLYQGNF-PSNRFNIRPGY-RWDGVDRSTGFEKDYIQRMNTRKNNAAEAHMWSVE-DM Mucci2 -----------------------------------------------------------------------------------MSNGQRATKAQIKAERAKHLEREERLSKQTVYRD-ATGKKVAEE--ARRRKEQIEKEARKMEWGKGLVQRREAEDERRRLEEEKHKPMARYADDE-DLNEELKERERWNDPAAPTYKGAW-KPNRFMIPPGY-RWDGVDRSTGFEDTFLLQQNQAKSFAAQAHAWSTE-DM Mydma EEYEYFAPSKSKADFVLTVS------------KLWTK-NFDTPV-INGAQR--KR-----TND-----------DSDLSPVRLTDTKKRSSREELQKESKRKNEEKNNMSTSTIYRDQKSGKKIIKK--KLQEEEKMKDLKKYAEWGKGVTQGKDYKQKLKDDVKEMQKPLARYKDDK-DLDDLLRNKSRDEDPM-PKYNGPTPPPNRFNIWPGY-RYDGVDRSNGFEKRRFMEISKRKSFETEKYKWSVE-DM Neucr2 DKAAYLAANKSSSST-----SKKRKRKNKSA-GLIIA-DDDGPV-LADFRK--AKWKTVGSSSEDIDAAAAADAAGG-DDEVLMSNGTHASASAITAKARQEAERLERIRAELVLRD-ATGRRIAEA--RRQQAEAERKEAEKKRALKGEVQLEQARRRREELEEAKLMPLARSKDDE-QLNAELKQQDRWNDPMAPTYKGPA-PPNRYGIKPGY-RWDGVDRSNGFEAERFKALNRRERNKGLEYAWQMD-E- Orpsp11 SLQKYVS---------------------------------------NNLRG--DNNKTV------------------------MSDGSLAAGKDLKLKRKQKAQQKAKMTSETIYRD-KYGKKVAKL--IAEERKKEEEAEKDMVWGKGLVQQREREEMVRKLRQEKDRSFAIYKDDE-ELNQEQMEKNRWGDPMAPRYNGPPPPPNRFNIEPGY-RWDGVDRSNGFEEKYFQMKNQKESISEVAYKWSTE-DM Pench1 SLADYLAKERPKK--------KRKKTKATDT-GLIIA-DDDRPY-FTEFRR--AKWKTIGG------EQEAADAPDD-EDAFMMESGARGTAAQTAAEKRRKAEEARDPSAATIYRD-ASGRIIAEA--RRAEEEKREKEEQAREALMGDVQRQQREERRQDLQAIKAMPLARTIEDE-EMNEDMRARDRWNDPAAPLYRGSF-QPNRYGIRPGH-RWDGVDRANGFEKDWFASRNKKSRFEALEYQWQMD-E- Phybl2 -TKEYIANSGTDENK------KKKKRKIGAKK---IV-DEEMAE-AKEAAK--SRWQTIR-GEDDNDNDD-SEL-ED-EKPMIMSSGQKATSHELKAARARELELKQRLKEDTVYRD-ATGRKIAEE--ARAKKEADERESRRMEWGKGLVQREEAQAELKRLKEEKDKPLARYVDDE-DYNQGLKDRDRWNDPAAPSYKGPW-KPNRFMIPPGY-RWDGVDRSNGFEDTFLLHLNQKKSLAAEAHAWSTE-DM Picst3 SRADYLL-------------KRKKKSKKIPSANVVIRADPRAPVKVKGFKR---------------------------------------VQAEREKPGK--------IEP-TVYRD-ALGRIVKQFE-QEKEAERDKRTFTELRTAEDEIERQQKEKYVPKQSQ-------------------------FEDPLLYVYNKGVNPSNRFGIRAGY-FWDGIDRSNGFEELVLRKQTEQKFQKMDSYDLDYE--- Plicr1 -MQAYLAESGPKADAILSRA-KKKRKAKADAP---LV-DED-AV-VRAFKK--RRWATIQEG--IKAESP-PP---D-EQPLVS---FTGTAEQLRKAQG--KRKEAAISAETVYRD-ASGKKIAEA--ARKKREKEEREAAKMEWGKGLVQREEQEKRRLEMERNRTKEFSRYADDK-DLNEDLKAQERWNDPAAPQYNGPPPPPNRFGIKPGY-RWDGVDRGNGFEKKLFQRSNERKRKGAESYSWSVD-DM Polpo -LPDYL-KSNDNNDD-----DTKKKKKSKSTS--VIK-DVDKPV-IDEFDD--EVWTTVDSSTRDDDLTP-PRANDDLTPPRNMSYGAEASGESIREQKKLHEQKERVADQTTVYRDS-RGKRL-----EKAKAEEE-ERRQDVLVKTSKMQRQQKEEQLRRLEEEKNRPFSRYADDE-NINQSMKDKDIWGDPMAPKYSGPAAPPNRYGIKPGH-RWDGVDRGNGFEKEYFRAQARSSAAKDEAYLWSVE-DM Pucgr2 -LQAYLASSGPKAEAIL---KSKKKGKPNESSGMILK-DVD-PV-VPTFKG--KAWETIKPSEEEEEEDE-REA-ED-ERPQISTNVVVGTAAEIRAASSRPT---REVSDDTVYRD-SKGKKIAEE--KRRQARELEKKMKKMEWGKGLVQRQDRKTDAEELSKIASQPFARTIDDK-DLNDELKGKQRWNDPAAPKYNGPPPPPNRYGIPPGF-RWDGVDRSNGFEKKLFQTGNDQKRLRAEAYNYSVD-EM Punst1 -MKAYLAASGPKADAILARTQKKKKKKKHADPPAFIK-DDD-AV-VRGFKK--RRWATIR------APTP-PPA-ED-EKPQVEDQPFVGTKSQIKKPSA--QVAKSKQPDETVYRD-ASGRRIAEA--ARKKREREEREARKMEWGKGLVQRDEEKKRREELEKARTRDVARYADDR-EMNEEMRAQERWNDPAAPEYSGPPPPPNRFGIKPGY-RWDGVDRGNGFEKRLFQKLNERKRAGREAYEWSVD-DM Rhior3 -----------------------------------------------------------------------------------MSNGQRATKDEIKAEKARQAERREQLQKETVYRD-VSGRKVAEE--ARRRKEQIEKEARRMEWGKGLVQRKAAEEEKKRLIEERDKPMARYVDDV-ELNQELKEKERWNDPAAPTYKGAW-KPNRFMIPPGH-RWDGVDRSTGFEDKLLLHQNQAKSRAAEAHAWSTE-DM Rhoto1 -LQAYLAASGPKADAILDRSRRKKKRKVEASSGLVIA-DEDKPV-VGQFKA--KAWATIREAD--RPPSPTPEP-ED-EAPAIVETAPRGTAADLRAERKAAEQERRKAEKETVYRD-ATGRRIAEE--AQKKREELEKQMAKMEWGKGLVQKSEKERRAEEAEKLKNMSFARHADDA-EMNEEMRETERWNDPAAPTYQGPPPPPNRFNIRPGY-RWDGVDRSNGFEKRLMERQNARGVFKAASQAWSME-DM Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ALHQYLSETKPKN-------TKKKK-KESKSDSLIVK-ERL-----SKFDK--QKWKNLETNE--------------------PSASSITSKNDLKEQEPLVT---------TIYRD-AQGHKIDDSSFSRSKYEAAEREQYLKNLNMGDVQKLGI-NVDAHDKKKNQT----------------ASSLTIEDPAIKLYDKPA-PENRFAIMPGS-RWDGVHRSNGFEEKWFAKQNEINEKKVQSYTLQEDY-- Salro SMAEYLAASGSGGGAGGGGARKRKKRRRKKDKKIVVD-DGDRPM-VADVTA--EVWKPALEQDHDSDDDASPPRDSDASPPRRASPPRRA-------PPRRPADRD------TIHRT-ADGRRMLKK--RQAEEELLQKQLKHMEWGRGLAQTDAARKKREEDAYEASRPLARTKDDE-DYNKELQSRIHADDPMAPTYRGPAPDPNRFGIMPGH-RWDGHDRSNGFERKLVASQGKRRARAEEAYKWSTE-NM Schco3 -KQAYLAASGPKADAILSKV-KKKKRKAPAAS---VV-HDD-AV-VRKFKK--RKWTTVAGGEQEDDGTP-PPA-ED-EKPMVA--PFTGSAAQLKKPQS--APAPE--SPETVYRD-ASGRKIAEA--ARLKREREEKEAAKMEWGKGLVQRQEREKQREELEKNRSLPFSRYKDDK-ELNEMQKEKEIWNDPMAPEYTGPPPPPNRFGIKPGY-RWDGVDRGNGFEKKLFQAQNSRKRTGLESYQWGAE-DM Schpo1 SNADYIAK------------GKKKKKKEKD--FVEIQ-DEDAPT-IESLKD--RDWKAVGNDE-----------QQDSHDAES-------TGKQVTFERRKREEKSSNLDEETVYRD-ATGRRIKEA--KRKLKEKEEEARRQKEQQQGVVQVRQQKEYLKELERQKTVPLARYEDDP-EYNKELKERSRWNDPAAATYQGYA-PPNRFNIRPGH-RWDGIIRGNGFENKWFQRQNERKAQEHEAHMWAIE-DM Sorma DKAAYLAANKPSSST------KKRKRKNKSS-GLIIA-DDDGPI-IADFKK--AKWKTVGSGSEDLEAAAAADAAGG-DDEVLMSNGTHASASAITARARQEAERLERIRAELVLRD-ATGRRIAEA--RRAQAEQERKEAEKIRALKGEVQLEQARRRREELEEAKLMPLARGKDDE-ALNAELKEQERWNDPMAPTYKGPA-PPNRYGIKPGY-RWDGVDRSNGFEGERFRAINRRERNKGLEYAWQMD-E- Sphar -LIKALPDDSPDLSP-----PRRTSRKHSPSQ------DSSSPV-----RR--HQ----------DDLSP-PRKSEDLSPPRRMADGTKAEASMVVERRKKEKEDRAKLDEATVRRDKKTGKKILQQ--RDADNKREAAEHAALRWGKGAVQERTQQQKMEDDIKVMAQPFARTADDK-DLNDMLKERHRAEDPMAPVYKGAAPPPNRYNIWPGY-RWDGVDRGNQFEKKLFTMQADASANAADYLAWATE-DM Spipu1 YLKKYMSS-----------NKKKRKKRPQPTS---II-DEEAPV-IPMFRS--DAWQTIRE----PSPSP-PPT---------LSDGRRATGAAIRQQEREMARQKSNLTPSTVYRD-KHGKKVAEL--AAMRRQREAQEEKDMVWGKGVVQQREAEQDAKRLEMEQDRPLAVYVDDV-ERNKELMDRDRWGDPMAPVYRGPPPPPNRFGIPPGY-RWDGVDRSNGFETRYFQAKNQRSAIQLEAYKWSTE-DM Sporo1 -LQAYLASSGAKADAILERSDKKRKKRKLDTTGLLVA-DQDKPV-VGQFKA--KSWSTIRGSDHQRSPSP-PPA-ED-EQPVV--VPSKGSAADLRAARLEAQRERLAAEQETVYRD-SSGRKIAEE--AKRKRQELEREMAKMEWGKGLVQREDKERMKREAEKLAKKGVARYADDE-EMNDELREVERWNDPAAPQYQGPPPPPNRFGIKPGY-RWDGVDRGTGFEAKYLQKKNSASMYRAAAHAYSTE-DM Stehi1 -MKAYLAESGPKADAILARE-KKKKRKAAFESGAKIV-DED-AV-VRGFKK--RRWATIR------EPTP-PLP-VD-EEPMVSKPAYRGSAKELAVAEA------VKMSKETVYRD-MSGRKIAEA--ARKKREREEREAKKMEWGKGLVQRGEEEERKKELEKIKGKEFTRRRDDE-EMNARLKDENRWNDPMAPEYTGPAPPPNRFGIKPGY-RWDGVDRGNGFEKKLFQRTNERKRRGQESYNWSVD-DM Tapde11 ---EYL-SNKSSS-------TKKRKRESK---SIVVD-DLDSPTIVSGFRP--AY-----------EEHPSPVAQSGTSEPGSMQSGARATQVAVAE-----RKERKEYSQSTVYRD-ATGRRIQEK--ARELKRAELRQEDERSMRQGLVQQQAREARAAELSKVRSEGFSRYAGHA-ASEAALKMKRRWDDPASPQYKGGF-APNRFSIRPGY-RWDGVDRGNGYEAKRFRQLADLAQRKTEYEDWAKE-DM Thetr CLADHLAKSALKVDKRVTAMVKEAQREAARAT------DAEPPPDVRELEATAARLAMVRAKAQGAADAPLTPVANDSERENKMAPGSAGSAGRVKAKRKRKRRRRRSMSGSTVYRN-KDGSRMAAA--ARKRRG----------WGTGLAQMASAQAQAAEARLVAATPLAQSSKDA-SVAALMQTKSRWDDPMAPRYTLGRPPANRFDIAPGY-RWDGVDRSNGFEARHLASSGFKSSSTA----------- Treme1 -LKAYLAASGPKADAILARSSKKRKKKKKEEDGLVLR-DEDAPV-VATFQK--SEWNTVASSSEAGPSSP-PPYKPD---PDAQITKRKGTAAQLREEEQAAAARS---EQETVHRD-ASGRIVEEE--KRKAEEEKRKAREREEWTKGLVQRKAREERSKEEREMGERDVARYANDT-RMNREMREVERWNDPAAPTYKGPY-GPNRFGIPPGY-RWDGVDRGNGFEAKYFQYQNTAARRQVAADQMT-E-DV Trire2 DLSNYIAS-KPS---------KKRKRKQGS--GLLITDDDDAPV-TAELRK--LKWKTVSE--NKDDSAAAADAADD-EMPVVMSDGTHASAAAVSARRRQQEEREERHRKNTVYRD-ATGRRIAEA--RRAAAEAEEKERLAKESLKGEVQQENARRRKEELENAKLMTFARTADDE-DMNRELKEQQRWNDPMMPVYAGAA-PPNRYGIKPGY-RWDGVDRGNGHEAERFKAINRRERNKGLDYAWQMD-E- Umbra1 -TKAYIASSGQEGQS------KKKKKKI-PKR---II-DEE-AT-VKSLYT--PKWTIIREGE--------EEA-ED-ERPQIMSSGHRVTTEQIKAIRLKKQRDKRELDPTTVYRD-KSGRKFAEE--ARRKKEELEKQERMMEWGKGLVQREEKAAEQKRLEEEKNKPLARYADDR-EFNDELKERELWNDPAAPTYQGQW-APNRFGIPPGY-RWDGVDRSNGFEKDYFLRQNARSARDAEAHAWSVE-DM Ustma22 KLQSYIAASGPKADAILARAVKRKKKKVKTDDGLVFK-DDS-QV-VKTFRK--IG--------SMSTPTPAPTS----EEP----TEFKATRDEMKALAREERKKRASLSVDTVYRD-SSGRIIAEQ--ERLERLRLEKQAERNTWSQGLVQKQQRQQAAAQLAAVQQQGIARRATDN-EYNEYFKQQQRVDDPAMPKYKGGW-PPNRFNIPPGY-RWDGVDRGNGYEKAFFERKAQLETRELQARAWGQS-DM Walse1 -KDLYLAESGPKADAILERA-KKKKSKSSTKD---TI-NED-QL-VSKFKS--IA--------------P-PTQSTE-DNPTVNDNDFKGSAKQIRQAQLRAKEEERLEEQSTIYRD-QSGRKIIEA--KRLKQERDEAEAKRMEWGKGLVQREDRDKLRKQEEAMKHKSLSKYSDDA-EHNAELMDVERWNDPAAPKYTGPPPPPNRFGISPGY-RWDGVDRSNGFEQKLFQSINSRKRAVYEHGKWSRE-DM Zygro1 SLNNYLND--GSD-------SKKKK-KSSDKKQLNIT-ESS-----DKTSK--PKWKNLDTNE-----------RED------LSSGAHATAEQMDSQKELDQRRQ------TVFRD-EKGNKILN---KEEKEKEVVRQRRIRELNMGEVQLFMVQNGLTRIPKERTK----------------EQSESFDDPARKLYANVY-PENRFGISPGC-RWDGVDRSNGFERKWFAKQNELNEKKQQEYALREDY-- [Cluster1894.fasta_al_trimmed; alignment length = 165] Allma1 TEQQNEVDVLKSIFF--EEFIEL-EPYAVLVRLYLTVEIPEPTFSVAASLAGEVVVYAVVAAMREKMAELARTKHAAEAERIAREEAADQAKFHGTPVTRERFLAWKADFDKEMTA---KAKAAERLTGRQLF-ETDKTLVTSDYMGDD--DSVDP-TLFEE--E Ashgo11 EEQKQELEVLESIYA--DDLTVVCGEFEVDLHLVVDITLPEPQLSIEDMLLGIQMCFALISSIKEDAESWFQKEEKEHERQLRERELEEQKKFRGTKVTHESYMSWRASFRQELGLDERDQERRMRLSGRQIF-E---------LAGEE--D------------E Aspfu1 EEQVEEREVLDSIFP--EEITDIS--YRISIALILQVSYPPPDLEIIEENLGMAMVFTLVSTLKESAELLMAERQAAKEMEAAKAEEEENRKFQGTAVTPETFLEWRERFRKEMEEKEQREREEKKLTGKQLW-E---------LAGKA--D--D-----EDDED Aurde31 E-LAEEIEILESIYP--DELSKVSDSLSFRVILTLALRFPPPEFDLGEQNLGTAMTFTLVSYLRDELLTLTRSRQQAARETERRALEAEEARTRGTPVTAASFAAWRAQFEKEMAARRVREEEERRPTGKQLF-ERDRNLAASDLADED--AAVDA-SQYESDED Batde5 EEQTTELDSLGYIFP--DELETLDESDEYATTFAIEFTYTPPLFKLGSESLGMGMIFAMVSHGKEQIEQLLTSREHDREQRILAEEEADRERYRGTLVTPDSFSAWRTKFLEEARQLKKAGAKLSKLTGRQMF-ERDQTLVSSDFMEEG--DVVDV-ELFDNDSA Botbo1 EILQEELEVLESIYP--DEIEKTSEQLQITVRLLLKVHYPPPDLAFGTESLGMAMVFTLVSHLREALATVVADRKKVERDRAVAEEEAEAARTRGTPVTTASFLEWREKFNKKMRLKAAQEEEERKPTGRQLF-ERDRNLATSDLVDED--ASVDV-SQYDDEED Botci1 -------------------MVYIS--YRVSITMLLQVKYPEPILDLIEENMGMAMIFTLVSTLKENAEQLIAQREKEQEQKLLAVEAEENKKFHGEPVTRESFMKWREGFQKEMEEIKVKEEAEEALTGRQLW-E---------MVGKV--E--D-----EDYDD Caeel EQQEQEIEALEAIYS--EEEIHVASRLSIQLDVELGIEFTEPIITLAEENLGMVMVFAIVSALQDEIGELVDVKEEKVEIEKEKKEAESRKKFEGTVVTPDTFRAWKDRFDEERKA---------RLTGRQLF-LRDATLNLSDLIGAQ--DEIDE-SLFDSEEE Canalb1 EEQAQEIEVLQSIYP--DELTLIN--FIIRISLNLIVKYPPPQLSISELNLGIPMIFNLITILKEESENLFNEKQCEFDEQQKIKELNEQKKFHGTKVTKQSWLNWRNNFRKEMKYELYDKQRFEKLTGKQIF-E---------LANQN--D--DE-E--EGENQ Cangl EEQEQELEVLRSIYP--DELEVVK-EFELQLTLHCTFQLPEPVISITDMLSGMQMCFALISSIKEKAEHYFLEQQKQHDQELQEREKEEQAKFHGTKVTRESFLGWRTKFRQEHGLDKRDEERRLRLTGKQMF-E---------IEGTL--DI----------DD Capow EEQAMEVEALMSIYP--EEYQEIEQSLRINATIVFNCTFTPPNFELALANIGTPMIFTIASAAKEWVESTLEARREAAEKEAQRLHE-EAIRAQGTPVTRENFLLWKLHFDRELDEQRQANNALKKPTGRQLF-EQDKSLGTSDILDEN--DVIDE-SLFEEEDE Catan2 QEQQNEVEILKSIFF--DEFIDLSDPYALALRLYLTVTVPEPELHLAASLAGEILVFTVVSALKEEMAAQATQLRAAEAERIRLEEEADNAKFRGTPVTIERFIEWKRKFDAEMAEKKLKAKAAEK-TGRQLF-ESDKSLVMSDFLGED--DSVDAHAMADEDDE Cioin EEQRDELEALESIYP--DSFTIVSTDFSLKISVTLKFTYAKPLFEVIEENLGCVMVFTIMSAVQEFLNQEDDRFQEEEERKEREMIEEQERKCAGTKVTVASFLAWKADFDLKMQ----------KLSGKEIF-LQSGDIEDESLLAGE--EEVDE-SLFDDEFD CocheC53 EEQKEEREVLESIFA--DEITDVS--FRVAVTIILNVSYPPPRLDIIEENLGMAMIFTLVTVLKDSAELLITERQALADMAAAKAEEEENKKFQGEAVTRESFLAWRERFRAEMAEEKRRKEEEKKLTGKELW-Q---------LIGKG--D--D-----DDDDN Coere1 DEQNDEIEILQSIYP--NEFEHSTDPLNISINLSLGIEYTTPDFTIYEKNLGMVMVFGMATDLKEIAVQLLVEKKRLKDARLQKEIEADRAKFVGTLVTREIFLQWKKRFDTEMSLRNTTLTDSSKLTGRQLF-EQDKSLAASDYFADG--DSVDT-RLFQDRPQ Conco1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 GVLTEEFEVLESIYP--TELTIVSERIELEVKLKLSVQYGDPEFSLGKENLGMAMTFTVVSHLREELSSLSKNRIQVEREKERLVIEAEEARTRGTPVTVESFKAWKAKFDKEVAQKKLREEEERRLSGRQLF-EKNRNMD-DDLLEEG--TSVDF-SQYEREEE Copci -----ESQVLESIYP--TELHRKSDTIEIEAKLLLAVHYPSPELKLGEENLGMAMTFTLVSHLREQLTNLARSNARLEAEME------QEARTRGTPVTVDSFKAWKAKFDKEIAAAKAREEEEKRLTGRQLF-ERNRNLDERDLIEEG--TSVDI-SQYQEDEE Croqu1 --MEEELEVLSVIF---DEGDLQSKTFKIKVEVELDLTLTEPLMEIANESLGDAMVYNIYSVLRQELGQVLSDRKRFEEEELRAAEEKEKSRAKGTPVTKETFLVWRAKFSKEIKLKEIKEQDEKKLTGRQLF-ESNRALVNSDLLEPD--AELDL-SAFSEETP CryneH991 AILDEEFEVLDSIFP--EET-----------TLNLIFEYPEPELIIAGESLGMAMSFTIASAAREALGVVISERKEEDDRRAREYEEAEAARTRGTPLTPDAFNIWRKTFTAELAAKREKAEEDRRPTGKQLF-ENSKVLATSDLYEEG--AEVDF-SKYREEEE Crypa2 EEQIEEREVLDSIFP--DEITDIN--FRISIVMVLTVRYPAPHLDLIEENMGMAMVFTLVTTLKEEAEQLVLRRARAHEEVLLAAEREENKKFHGTPVTRDTFLQWRDGFIREMEEQRVRDE-EERLTGRQLW-E---------LA-KG--E--A-----EAEDD Debha1 EEQQLELEVLESIYP--DELTKYS--FSIKLRLLLDVRYPAPELDIADLQVGMPSVFALATQLKDEAEFLFQNKQKKYDADSLAKEMEEQKKFHGTKVTKDSWNEWRTKFREEMKVAEKDLENFNKLSGKEIF-E---------LAGDD--E------------- Dekbr2 EEQKQEIEILKTIYP--EELEILS--FTINLAVKLHIRYPAPELWVAKMNIGMPSVFTLASVLKDDAEQMFNKKTQKLEQARVSREKQEQKKFIGTKVTRENFEAWQVKFRKEMGIKERKEKRFEKLTGKEIF-E---------LAGEE--G--EP-Q--AADDI Dicdi EEKDMEVEALSAIYM--DHFNSIDSDVQITLAIILDIIFSVPKIDLAENNIGMSMIFILCGLIKE----WVDENDLEESEQSSSSEAEDDERFEGTPVTEEAFLAWRKKFIEETKPFKK------KLTGRQLF-EQDTSLNASDLMEEG--EQVDW-SLFDYEEE Dmel EDQTNEVEALDSIYC--GDMEILATEFQIPIACKLVFTFTAPVVEIIEENLGMEMIFSLVSSAQEWLNERWDEHEELREQKLREIEEEERKKFEGTRVTVESFLKWKLEFE--------------KQTGRELF-MCDNTLNDSDLEAGENIEKIDE-TLFDDDDD Enthi ---QTEVETLSAIYG--DKV------LSCTIEITIKFSIPEPTFVLIEEEF--TCLFELVDHVKDMLIEILKEQNEEIVRKEKEEERAREREFIGT--TKKTFEEWWKDKEKERKITLEKIKKEKRMTGKEFFMNNENKEEEEDLKEQG----VDL-EMF----- Falba EMQQQELEALQCIFT--EEYEELSTEFKLNLSLSLLFTLGLPTIEIAQDNLGMPSTFTIASEVQEWMVSRFKRAEAEESRRAAEEEEAERNRFAGSRVTALTFFEWKRKFDAEMALLEQQANAQNKLTARKGLRDRSRSSSSSRRMRLGACD-----A------- Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 EDQVEEREVLESIFP--EEITDIS--FRVSVTMLLQVRYPEPHLDIIQENLGMAMIFAIVSTLKDNAEQLVQERTRAHEEAAQAAEAEENKKFHGTRVTPETFIKWREGFIKEMEDKRQQEE-DDRLTGRQLW-E---------LAGKG--D--------EEDDD Galma1 DALLEEFEVLESIYP--TELHRLSENIEIEAQVTLCVHYNDPILALGEENLGMAMTFTLVSHLREQLSQLVRSKGKIEAEKERLALEEEEKRTRGTPVTAESFMIWKTKFDKETATKKMQDEEERRLSGRQLF-ERNKDL--DDLVEEG--ASVDI-SQYNNDEE Ganpr1 EEQAQELEALRSIYD--FDLEELADELGLPAHVVLQFELPKPDISFAEENLGMASSFTLVSHLKERVEDILRQKKRAEEEKHRLAEEAERRRIEGTKVTPESFAAWKGRFDREMAEANR------KLTGRQLF-ENDQNLAKSDLMEAG--DAVDV-DLFDEDDE Gloin1 EEQEQELEVLKSIYP--EEFEEISE-FRIRLTLGLYIKFTPPEISIAQDSLGMAMVFTLSSLLKDLLTSFVIERKKVEEDKIRKEIEAEQAKFQGTKVTVASFLEWKENFDKELEEKEKATKSLA-LTGRQLF-EQDESLAKSDYMEEG--DTVDV-SLFSDEEE Hisca1 EDQQEERETLRSIFP--DEITDIS--YRISITLILQVSYPPPDLELIEENMGMAMIFTIVDTLKEGAELLISERQALKEMESAKAEEEENRKFHGTAVTRESFLEWRARFQNEMEELERRKQEEKKLTGKELW-E---------LAGKV--D--D-----EDYVD Klula1 EEQTQELEILESIYP--DEFTVLNSELQIDIILHTIFTLPEPLIKIEDMLLGMQMCFALISNIKDYAEQWFQEKEKEHDRLLLEREKEEQKKFRGTKVTRESYIEWRAKFRKELGLDERDAQRRLRLSGRQIF-E---------LAGDE--D-----------DE Lacbi2 EVLLEELEVLESIYP--TELQRVSERVRIEAKVTLCVSYPDPNLSLGEENLGMAMTFTLVSHLREQLSKLVQSK-------ER----AEEARTRGTPVTPESFKVWKTNFDKELALKKAQEDDDKRLTGRQLF-ERNKGI--EDLLEEG--TSVDI-SQYREEME Lenti61 EVLTEEFEVLESIYP--DELTKLSERIRIDVSVALNVEYPDPKFSLGEENLGMAMTFTLITYLRERLSVFMREKRKEEMEMERRTLEAEEAKTRGTPVTVESFKAWKIKFDKEMAVKRMREEEERRLSGRQLF-ERDRNLGTLDLNEED--ASVDI-SQYEDEDN Malgl1 QVLSEEMEVLESIYI--EELEK-------------------PTLSIASESLGMPMVFTLASHLREALTDYMTRQEKDAQKKREAELRAEEEKFRGTAVTLERFKVWRVEFMKKQAALKAEKEEAHKPTGREIF-SKDARV--EEVTDES--VEVDF-SLYEGEEQ Mellp23 --MEEELEVLTVIF---DEADFQVKHFLMRVEVDLDLTPQDPLIEIANESVGDAMGYTLYTELRQELGRVLIDRKKREEDELRAAEEQEKNRAKGTPVNKETFMIWRTKFNETIKLQQKKIEDEKKFTGRQLF-ESNKALVNSDLLEPD--AEIDL-SSFLDDIP Mnele EEQESELEALESIYV--TELEILSRDYNITIMVGLEFKLPEPQIEFAENELGCVMIFTLVSELQDKVNEYVDNIMEEKEERDKVPV------FHGTPVTLESFTEWNNKF---------------KLTGRQIFLAKDGNIDISD-IGDAEEDEVDE-SLFELEDE Monbr QEQADELTALESIFI--DELEILKRDYNIHIKVTLNITYTAPNWKLIEENLGMGMAFAMQAALKEAVDDYNAENVRERQAQKEAEEQAELERTAGTLLTPETFDEWNTAFIEEQRAKRDQKAAEAKLTGREIF----EQYRRSGY-EEG--DPIDV-AVFDDLDD Morel2 EEQANELEALQSIYP--DEYEEISADFTILIAMKLHVKYTEPEFSFAEEAIGMGMVFSMASIAKDTLSEIIVNNEREEEEKAQRELEEEEKRKEGTRVTVELFTRWKTAFDSEMAEKERIEKGL--PTGRQLF-ERDHSLAKSDFMEEG--DDVDI-ALFDDEDE Mucci2 EEQANEIEALESIYP--DEFQAISE-FKIAVGLSLHVTYTPPEYEIAEDSIGMAMIFTMVMTMKEELDNIMLDVEEIINEKRRKEEEAEQAKFVGTKVTVENFMEWKKKFDAEMLEKDAVLKA---LTGRQLF-EQDKSLALSDYMDEG--DSVDA-SQFFDDDN Mydma DEQDIEIEALESIYS--EELEIISRKFLIRVSIQLQFNFVEPLIQVAEENLGAVMIFTLVSEAQERLLDFIQDIKDIQLEKDRIALEQERLDYKGTPVTMENFLAWKIQFDEEMRIIGKRKTE--KLTGKQLF-ERDSSLIDSDFIND--QGKVDE-SLFDLDD- Neucr2 EEQIEEREVLDSIFP--DEIQDIS--YRITISMVLTVRYPEPFLELIEENLGMAMIFTVVSALKDAAEQLAVERIKAQEEAALAAEREENKKFQGTPVNRETFLKWRESFLQELEDQRIKEE-EEKLTGKQLW-E---------LAGKG--D--D-----EGDDD Orpsp11 EEQQQELEALESIYF--DEFEKINDEFRILISLYLYIEYPEPIMEIAEENLGLGMVFTLSSQLKETIDALVVEREREEEERIRREEEEERKKHEGTKVTVESFLAWKAKFDKEMQELEEENQIKQVLTGRQLF-EQDTTLLDSDFAEEG--DEVDL-ALFDDEDE Pench1 EDQIEEREVLDSIFP--DEITDLS--YRVSIVICLEVSYPEPNLGIIEENLGMPMIFTLVSALKESAELLMTERQAEIEEAAAKREEEENRKFQGTAVTVQSFLEWSAKFKKEQEEEELRAREEKKLTGRQLW-E---------LA-KG--D--D-----EEDDD Phybl2 EEQQNELEALESIYP--EEFEAISE-FRITITVVLHVKYTPPEYNIGEDSLGMAMIFTLASIIKEELNQIVLDADEVEEERKRKEEEIEQAKFRGTKLTVERFMAWKAEFDKEMEAKEDKEKI---LNGRQLF-EQDKSLALSDYMDEG--DSVDV-SQFEDED- Picst3 DEQREEVEVLQSIYP--DELVVIS--YKIRITLALDVRYPAPDLDVANNQIGIPMVFALASQLKDDAEQLFKDNQAEYDRELLERERIEQQKFNGTPVTKESFAAWRDKFRKEMNYEEKQRQKFRKLTGREIF-E---------LAHEE--E--D---------- Plicr1 DVLLEEYEVLESIYP--TELEKISERIRIDVKLSLGVHYPDPDLSLGEDNIGMAMTFTLVSHLRERLASLVQVR--------------EEARTRGTPVTVESFRAWKIKFDKELAAIKAREEEERRPSGRQLF-ERDTTL--EELMEEG--TSVDF-SQYDDEDE Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 EQRKEEIEVLQSIF---EDLSFESDEVILRTTVNLKIKYTEPDIEIGRESLGMAMIFTLSLALQQELARILSDRVRLEKEEIKQAEEAEAARKKGTPINKETFSIWRAKFHEQNQLKKAKEEEERKLTGRQLF-ESNQALITPDLIDAD--AEFDL-SQF-EDEP Punst1 EALLEEYEVLESIYP--TELSKLSERVAIEVKLTLNVHYPDPDLTLGQDNIGMAMTFTLVSHLREKLAVLVRERKKEEMEKERRALEAEEALTRGTPVTVDSFKAWKAKFDKEMAEKKAKEEDEKRLSGRQLF-ERNRDLVSADLADE---GSVDI-RQYEEEE- Rhior3 EEQKNEIEALQSIYP--EEFEG---------ALSLHVTYTPPEYEIAEESIGMAMVFSMVMIIKEELDNILLDVEELANEKKRKEEEAEHAKFVGTKVTRESFMDWKKKFDAELAEKDAVLIA---LPGRALF-EQDKTLALSDYMDEG--DSVDI-SQFLDEEE Rhoto1 EERRSELEVLESIFP--DELTVLSDEISVRVTLNLVVTYTPPELELAEDNLGMAMVYTLALQLKELIAEMLVKRAREDEERYRREEEAVAAKKRGTPVTKESFAAWASKFESEFAEQRRREEEERKLTGRQLF-EQGKVIDSDAFGEEG--DAIDI-SQYDDEDD Rozal11 -EQTEEYEVLLSIFP--DELKKLG------------FVLPPPEVFLAEQNRGMVMLFTLISHI----NSVVEERRLEAERMEQLSLEPELKGKNGTPVTAETFAKWKAAFDKERMESKE------KLTGRQMF-EKDKTLIASDLAEQGILD-----SLFEDENE Sacce1 EEQKQELEVLESIYP--DELRIINDEFEVAITIIAEFKLPECLISLTDMLLGMQMCFALISSIKERCEQWYSEQEKQYELEAQEREKKEQAKFHGTKVTRESYLEWRSKFRQELKLDERDQVRRMKLTGKQMF-E---------VVGTG--DYME-------EDD Salro QEQLDEVESLEAIYP--DLFTKLSDDFKLVISVTLTVTYTPP---VIEDNLGMPMVSVVQMTVKEALDEINEQEVDDRIRAKEEAEMKELERTAGTAVTKESFMAWLTQF-QEEMAKKKGAPAKAKLTGKQLF-LTDTKMQTSDFMEEG--DDVDR-ALF----- Schco3 DTLAEEYEVLESIYP--TELSKTSERIRIEAKLALKVHYTDPDLSFGEENLGLAMVFTLVTTLRERLSELVRERKAEEHEKERLAIEAEEAKTRGTPVTAESFKAWKAKFDAELAIKKAKAEEEKRLSGRQLF-EKNKNL--EDLVEEG--GSVDI-SQYEEEQE Schpo1 -AIEEEREILESIYP--EEFKCINDSFEITQSLIFTCQLSEPDVKIAEECLGMAMIFSLCSVAKEETNAILIEQTQAIEERHRKEAEQENKKFHGTPVTVESFTEWKKGFDAWRNEQLKLEQESKRMTGRELF-EN--NLVKLD-------D--------EGEA- Sorma EEQIEEREVLDSIFP--DEIQ-----YRITISMVLTVRYPEPSLELIEENLGMAMIFTVVSTLKDAAEQLAVERIKAQEEAAQAAEREENKKFQGTPVNRETFLKWRNDFMQELEEQRIREE-DEKLTGKQLW-E---------LAKGG--D--D-----EGDDD Sphar ETQLEELEVLESIFP--EEYKELTREFEITLELTLAFELPPPEITTALENIGDVMVFVIASHAKEWLDTRMDGVQS-------------------------------------------------R-----------------------AQEGVYI--------- Spipu1 EEQANELEALRSIFP--DEFEELDVGFRIHISLYLTITYTEPELSLATEYVGMAMVFTLATSAKETFERLLQERATEEAARIAAEEEAERQRHAGTRVTPATFDIWKAKFLEEIAGILKQPKGEE-LTGRQLF-EKDQSLAKSDFIEEG--DTVDV-ELFDDEDE Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 DVLIEEFEVLESIYP--DEFTKLTERIKIDVKLSLSVQYPDPELTLGEENMGMAMTFAMVSNLREQLSTLIHHRQKAEM-------EKEQARTRGTPVTVDTFMQWKKKFDQEIKIRKTRQEEERRPTGRQLF-ERDRTLAIEDLVEEG--TSVDV-TQYDDEEE Tapde11 AIE-EEEEILLSIFP--DEFEKVN--FRIRITMYLIAQLPPPILHIVQENLGMAMVFTLVSALKEHGTALLDDRERAQRDAKLALEREEQKRFEGTKVTAQSFAAWNANFKLEQLQRQADEEEAAKLTGRQLF-EGDKTLAQSDTRSKG--D--------EEDDE Thetr EEQASELEVLESIYPSSDEFKVLCHEFEVLVEMPLAHRLRPPSWTLVEDSIGDIMVFSMVQAARDALDELAEDAAEIKAAEAAAFAAAEEAR-KGTAVTRELFAQWAPDFNDVIRAQRRERAEAMRLSGRAIF-ESDDSEAPSETAADAAADTVNA-ALFDSDSD Treme1 AILDEEFEVLESIFP--PEEQRKNERMAILVSIYIIVNYPPPLFSLAEESVGMAMTFTLVSAIKESLMELIHERKEEDDRRAREYEEVEAKKTRGTPLTRETFEQWRKGYMSELKIKREKEEEERRPTGKTLF-EVGG--AMEDLYEEE--SEVDL-TQYEEEEE Trire2 EEQVEEREVLESIFP--DEITDIS--FRIKVHFLLSVRYPDPHLDIITENLGMAMVFTLYSSLKEAAEQLIQDREKAREEEQLAAEREENKKFHGTPVTPETFMKWREGFLKEMEEKRLREE-EERLTGRQLW-E---------LAGKG--E--------EEEEE Umbra1 EEQQNELEALQSIYP--DEFEDLGA-FRIICVLALKVKYTPPEFEVAEESIGMAMIFTMASMLQEELYVVISEGIEAELARVRLAEEAENRKFKGTPVTVDLFLTWKTKFDKEMAEKEQEAKG---LTGRQLF-EQDKTLASSDYMDEG--DAVDV-TQFDDEEE Ustma22 ATLAEELEVLESIYI--DELETVSSELRIRIVLSLDIQCTPPNMSIAQDSLGMAMVFTLASHLRESVTTLIQRREAAASAKREAEIEAEAEKFRGTAVTPERFAEWRLRFLQEMAEKEKKEEEAKKPSGKQLF-EKGGTF--EDAAEEG--AEVDW-SLYEREEQ Walse1 EIITEEYEVLESIYP--EELERISDRLKITTKTDLRITYTEPDFEIGQESLGMPLVFSLASALKDGISQLVQDREQAESDRKQAEIEKELERTRGTQITRENFLEWRSQYIAERNAEIARKEEAERKSGRQLF-EKDRTLADSDLMNKG--DGIDL-RKFDQDNQ Zygro1 EEQNQELEVLESIYP--DELQVMKRTFRILLSIEVDFHLPAPIIALDDMLLGMQMCFALLTSIKDHCESWFQEQEKEHERELQEREKEEQRKFLGTAVTPKSFLEWRAKFRKEFKIDERDSSRRSRLTGRQIF-E---------LAGEE--E--E-------EPN [Cluster1909.fasta_al_trimmed; alignment length = 108] Allma1 I-DLTTLQLQAVRQQLDEEITHLTSSFTQLKQAQAKFSACIEALRAILVPLTNSLYVPGKL-NNTERVIVDVGTGYYVDKYKRKVEFLQGNLDTLQQTIIAKQLVEVL Ashgo11 I-DLTTLQLAQVKQQFDQELQHFTKSLQALSMARAKFNECIADVQRLLVPLAGSLYVPGKV-VNNQKFMVDIGTGYYVEKYQKKVNKLNKEAVQIQDIIKEKTIEAQM Aspfu1 V-NITSLQLRALQTRLTSELEHLTTSHQKLRAAQSRFRDCVRSIDDILVPLTSSLYVRGKL-ADREKVLVDVGTGFYVEK---------------------------- Aurde31 I-SVADLQLADVRRQLQEELELFTTSFSQLRALQAKFRACIESSKPILVPLTNSLYVPGKL-ADGEHVLIDVGTGFFVKKYRAKVEGLQENIDKVQETIARKQVQQIM Batde5 I-KLEELQLQAVRQQLEEEIQTLTQSFAQLKQAQAKFNDSIESLKDILVPLTTSITMTSQL-ADIKTVIVDVGTGYMIEKYKRKVEYLKLNLEKLQETVVQRQVVEMI Botbo1 V-DVADLQLLDVKRQLDEELTHLTNSFTQLKQAQGKFKACVENIRTILVPLSNSLYVPGRL-SDPDNVIVDVGTGYYVKKYQSKVDFVQKNLDTLQETITKKQLLSLL Botci1 I-DLTSLQLTQVKKQLDDELEHLTSSFQQLRAAQNKFRECLRSIKPILVPLTTSLYVPGEL-ADTENVIVDIGTGFYVEKYEAKVEEIGTNLKDLEIIVNNKSVEDVL Caeel V-PLSELQLGELQKNCEQELNFFQESFNALKGLLTRNEKSISALHTALIPLSESLYIRAEL-SDPSKHLVEIGTGYFVELFDRKKEHITKQVETVEGILKEKRISDAF Canalb1 I-DLNSLQLIEFRKSIDEEITHFTQSLQALSAAQSKLKDCISSINDLLVPLTSSLYIPGQV-VTRNKYLVDIGTGYYVEKYNNKIKKLDDDAKKLKNILVQKNVNLIL Cangl I-DLSTLQLAVVKQQLDQEIQHFSQSLQALNMAKTKFTECIEDVQPILVPGSSSLYIPGEI-VESKSFMVDIGTGYYVEKYQKKIDKLNTESVQIQNIIKEKSLENQI Capow M-SLLAMQLQTFAKQMDEEVRFLIQSLSQLHQAVKRFEESRDSLSDLLVPLTSSLYVPGTL-ANAGKVMVDIGADYYVERFSRRIAFLMDNIEKLQKTIGTKRLQDII Catan2 VINLDNIQLQAIQEQLSNEIQALTNSFTQLKQAQAKFTDCRASLKSMLIPLTNSLYVQGRL-SNPDRVIVDVGTGYYVEKYQRKTDYIKENLEKLQATIVSKQISQVA Cioin I-NLTTLQLKMLHDQFDSEIEYLTSSMQSLKGAQTQFESSKRCLKSVLVPLTSSLYVPANL-VDTNKVLIDIGTNYYVEKFKRKSDYVKQQMEKFQPILQHKFIVEVM CocheC53 I-EITSLRLQELKTQLDAELTHLSNSFQSLRTAQSKFKDCLTSIKPLLVPLTSSLYVPGKL-TDHEHVLVDVGTGFFVEKYERKVKDLGESLKDLEQVVQGKAVEEVI Coere1 I-SLEELQLQNIKNQLETEISGLTEAFTQMKQAQGAFRECKNCIKTIMVPLSNSLYVPGKI-SNIDSVVVDVGTGYYVEKYDGKIEYVQGNLKKIQETMEQKQLMEVM Conco1 LIDLTSLTLKQVRTQLDEEISVLSNSFSQLKRAQSTFADCGSCLQKMLIPLTSSLYVPGQV-KDIEKVIIDVGTGYYVEKFDEKTEFIGNGLKDLEQNITGKQVLQVI Conpu1 I-NIGDLQLAEVRRQLDSELQHLSSSFQQLKQAQAKFKSCIENVTTLLVPLTNSLYIPGRL-NDAENVIVDVGTGYYVKKYKAKVDYIAKNLDTLGDTLQKKQIINVM Copci VINIADLQLGEIKKQLEEELNHLTSSFAKLKQAQGKFKACVQNVKTILVPLTNSLYVPGKL-TDTKYVIVDVGTGYYVKKYEAKIDYLQTNLVKLEDTINRKRVVNVI Croqu1 --------------------MHLTNSFAQLRSAMTKFTNGIEAISSVLVPLTASLYVPGRL-KDRSRVMVDVGTGYMIEQLNQKVLALGVNLDQLQATIETKQVNELI CryneH991 V-QLTDLQLQEVKKQLDQELDHLTTSYSQLKQAQTKFKSCIANVKEVLIPLTSSLYVPGKL-TDVENVVIDVGTGYYIKKYTSKSEFVQTNLDTLQQSIETKQVQQVL Crypa2 V-SLDSLQLTAVKKQLDEEVDHLTTSFAQLQAAQIKFRDCLRCVKEVLVPLTNSLYAKGNI-SRPDRVLVDIGTGFFVEKYEGKIKDLSSNIADLEGIVQNKTVEEVL Debha1 I-DLTQLQIIEFRKSTEQEINHFTQSLQALQTAQSRLKECINSVSELLVPLTSSLYLPGKI-AKKDEYLVDIGTGYFVNKYESKIEKLNGDSKKLKEILVQKNINLVL Dekbr2 ----------------------------------MKYKECHSDVQDIMVPLTASLYVPGKI-KDSDNFLIDVGTGYYVEKFQGRLDKLKEDSSKLTSLIKEKVVDQVL Dicdi V-NLGSLQLQMVREQVEAEIQQLSESIQQLKHASNKYIEAKEAMKDMLVPLTSSIYLPGKI-NSNEKVLVDIGTGYYVEMSNRKVQLITEQVNKVQTAINMKRIVQVA Dmel I-DLTKLQLIQIKQEFEQEITNVQDSLSTLHGCQAKYAGSKEALRQILVPLTSSMYVPGRV-KDLNRFVIDIGTGYYIEKFKRRVEYVQEQIEKIEKIHLQKTVMSVL Enthi I-PLTSLDLAGLHKTLQNELQNLQASYEQLFSVQQTYLDNKSIIQPMLVPMNSSLYMKGDI-DSYDRVIIDIGANYFVSKYDRKIKLIEGEKEKILKIVSSRKVQEQM Falba F-DLSRLQLQEAQRQMSQEINMLTSSYSVLRESKMRFLSSAAALKNIMLPITTSLYVPGTL-TDVNHVLVDVGTDYFIKMYERKDAMLDAELAQLNASIQQAQLVEFM Fomme1 MVNVADLQLRDVRRQLEEELTHLTASFQQLKLAQAKFRTCLSNVRKILVPLTNSLYVPGKL-SDLEHVIVDVGTGYYVKKYTVKIDFVKGNIETLQEALTKKQVMNLI Fusgr1 I-NLDTLQLAQVKKQLDEELEHLTTSFAQLHAAQNKFKDCLRCVNSVLVPLTNSLYVRGEL-SDADTVLVDIGTGFLIEKYESKVEELGTNLKDLEVIVQRKQIEEVL Galma1 I-NISDLQLSEVRKQLEDELNHLTNSFAQLKQAQAKFKACLENVKTILVPLTNSLYVPGKL-ADPEHVIVDIGTGYYVKKYADKVEYIRTNVDTLEDTIQKKRLTSLL Ganpr1 I-ALASLQLQNLKQSLEEELQQLTQSYAALRQAEVKFSENTTTLKPMLVPLTSSLYVPGEV-TAVENVIVDVGTGYYVEKYSKKAQYVKGQLEKLAETLNSRQIAEAM Gloin1 I-ELSDLQLVEIKKQLEEELAHLTASYEKLKQAQTRFQDCIDSV-ILLVPLTQSLYVPGEL-VDTDKVMVDVGTGYYVEKYSDKVEYVKKNVETLRQTILTKQTIDIM Hisca1 I-DLAALQLRALQARLSSELEHLTSSHAKLRNAQSKFRDCIRSIDEILVPLTNSLYVKGRL-ADRKNVIVDVGTGFFVEKYNGKVGELGTNLRELEKVVQAKSIEDVL Klula1 I-DLTQLQLTVVKQQIDQELQHFTQSLHALNMARSKFKECIDDIQNLLVPLSGSLYVSGKI-QDNKKFMVDVGTGYYVDKYQKKVDKLNKESLQIQEIIKEKNIENQL Lacbi2 ------------------------------------------------------------------------------------------------------------ Lenti61 V-NVTDLQLADVRRQLEEELSHLSNSYTQLRQAQAKFRSCIENVKTILVPLTNSLYVPGKL-SDTEYVIVDVGTGYYVKKYESKVEFIRTNLEALQETITKKQLINVL Malgl1 ------------------------------------------------------------------------------------------------------------ Mellp23 L-NVQDLQLNSVKEQLEQEIVHFTTLFAQLRSATSKYTNGIEAIDQVLVPLTASLYVPGKL-KDRNRVMVDVGTGYMIDQLNQKVLSLGVQLDQLQAVIETKQVKELI Mnele V-DLAQLQLNQLRAQFEEEEQMLTQSLAQLKGVQSRFIESQESVKDVLVPLTSSMYVPGQL-ANTDKVLIDIGTGYHVKMFTRITEYITKKMEVVQKNLIEKDTTEIL Monbr --------MQAFHDQISQDLQVIAQSIGNFKLVQAKYISAKESLKEMMVPITESLYVNSKV-KGDGKVVIELGTGYFVEKFDRKIDFVTKRMSELQNVARGKNVVQIL Morel2 I-ELQDLQLVEVKKQLEEELSHLTSSFGQLKQAQNRFADCIESCKTILVPLTSSLYVPGKL-ANVEKVIVDIGTGYYVEKYNGKVDFVKDNLDKIQATVAQKQLVDMM Mucci2 V-NIADLSLQQVKTQLEEELSHLTQSYSKLKSVQGRFTDCADSV--------SHLYVPGKL-SNVSKVIVDVGTGYYIEKYNDKVGYVKKNLGTLEKTITDKQIVNVM Mydma I-PLSQLQLDQIKRDIEQEISVLSDSLNALKSAQQKFSDSLDNLKALMVPITSSMYIPGIM-DTSEKVLVDIGTGYYAEKFRRKIEFVAKQIDKVHPALSEKSLIEEL Neucr2 V-NIESLQLTAVKQQLDEEVEHLTASYTQLAAAQAKFKECLRIVKDILVPLTNSLYVKGKL-SNPDRVIVDVGTGFYVEKYDAKVKELGANIQNLEAIVQGKTVEEVL Orpsp11 --------------------------------------------------------------------------------FEKKNSFLKDNLSKLQKSIISRQIIEVL Pench1 I-NLASLQLRALQTRLTSELEHLTTSHTKLRAAQAKFRDCVRSIDEILVPLTSSLYVKGRL-TDREKVLVDVGTGFYVEKYDDKVKGLDANLQELEKIVQTKSVEETL Phybl2 V-NLNDLSLQQVKNQLEEELSHLTQSYSKLKGAQSRFTDCADSVKTILVPLTSSLYVPGKL-SNVEKVIVDVGTGYYIEKYTDKVNYVKQNLEKLQEAVTGKQIVSVM Picst3 V-DLNSLQLVEFRKSIDQEINHFTQSLQALQTAQSKLRECISSIDDLLIPLTSSLYLPGKS-IKKNEFLVDIGTGYFVEKYDYKITKLNDDGRKLKDILVQKNVNLVL Plicr1 V-NVGDLQLSDVRRQLEEELTHLTNSFAQLKQAQAKFKSCIDNVKTILVPLTNSLYVPGKL-CDLENVIVDVGTGYYVQKYESKVDYIRTNLEALQETIQKKQLVNIM Polpo V-NLAALQLEMVKEQVENEIQTLSDSMLQLKHAATKYLEAKEAIKEILVPLTSSLYLPGKI-NCKDKVMVDIGTQYFIEMTNRKVQLIQDQVNKVQQAVNVKRIIQVA Pucgr2 L-NVQDLQLASVKEQLDQELIHLTNSFAQLQNAIGKFNSGIEAIEPILVPLTASLYVPGKL-KDPSRIMLDVGTGYLIDQLNRKVLGLGLSLDQLQNTIETKQVRELI Punst1 I-NVTDLQLSDVRRQLEEELTHLTNSFTQLKAALAKFSACIENVKTTLVPLTNSLYVPGKL-CDVENVIVDVGTGYYVKKYQAKVDFVRGNLETLQDTITKKQLLTVI Rhior3 V-NITDLSLQQVKSQLEEELNHLTQSYSKLKAVQGRFTDCAESV--------------GKL-SNVSKVIVDIGTGYFVEKYKDKVEFVKNNLVTLEKTITDKQIVNVM Rhoto1 V-SLQDLQIGQVRSQLEQELKHLTAAFGDLKAAQSKFMACMDSLKKVLIPLTGSLYVPGRI-ADPENVLVDIGTGYFVEKYNAKVLALKSNLATLQQQIEKKQCGEMM Rozal11 VNALLQMQLQQIKAQIDQDLNVLTSSFSQLKIAQAKFYKSHECLKEVFIPLTQSLYVPGKM-SNINKVAVDIGTGYFAEKFKRKTEFIQNQLSKLQESVAEKKVLDVI Sacce1 I-DLTKLQLNAVKQQFDQELQHFTQSLQALTMAKGKFTECIDDIQKLLVPASASLYIPGKI-VDNKKFMVDIGTGYYVEKYQKKVDKLNKESVQIQDIIKEKTIEAQI Salro I-DIMRVQLESVRQSLSQEVQTLTTAIKSLKHAQTKFSNSLESIKKSLVPLTESLYVYAEL-TDPSKILVDIGTGYYVEKFQRKVKFLTEQLQGVQVVASEKQVAEAY Schco3 V-NISDLSLAEVKRQLEEELSHLTNSLVQLKQAQSKFKSCIENVKTILVPLTNSLYVPGKL-CDTERVLVDVGTGYFVQKYTDKVDFIQKNVETLDETIAKKRLIQVM Schpo1 V-DLTSLQLSEVIKQLDSELEYLSTSYGQLGRAQLKFRECLANVKEVLVPLTSSLYVPGKLNLGNSKLLVDIGTGYYVEKYKRKCEYLASSIENLNNAIDAKSVQNIM Sorma V-NIESLQLTAVKKQLDEEVEHLTASYTQLAAAQAKFKECLRIVKDILVPLTNSLYVKGKL-SNPDRVIVDVGTGFYVEKYDAKVKELGANIQNLESIVQGKTVEEVL Sphar V-DLNTLALANLKEQTEEEIQYLAQSKSQLELAAKKFVVAKQAVAQVLVPMTKSLYVPGKL-SNVEKVVVELGTGYYVEKYDRRLEYLQTNIQGIVNHLNSKQV---- Spipu1 I-DPMQIQLKAMHNTIGEEIETFTNSFAQLKQVHAKYNDCMESLKTLLVPLTSSLYVPGEL-ADLENVILDVGTGYYIEKYKRKIEYVKSNLDKLQETINDRRLTDLI Sporo1 V-SLEDLQIASVRQQLEQELKHLTQAFGDLKAAQSKFLACMESLKKVLIPLTSSLYVPGKI-QDTDNVIVDIGTGYFVEKYNTKVLALKSNLATLQQQIEKKQCGEMM Stehi1 I-SIADLQLADVRRQLDEELTHLTNSFAQLKQAQAKFKGCIESVKSILVPLTSSLYVPGKL-CDLENVIVDVGTGYYVQKYESKVQYIESNLDTLQEAIQKKQLVNVM Tapde11 V-DLTTLQLQEIRKQLDQELEYMTNSHMQLRQAKAKFLSCTESVKQILVPLTSSLYVPANIHTDPKRVIVDIGTGYFIEKYTKKVGFLDTNLTDLEKIINAKGVTEVM Thetr V-DLRSLKLQMVGKSLEQDLENLTASYSGLSVAAAKFRTSRASLKDVLLPLTTSMYVPGKL-ADVSKVMVDVGTGYYVEKFDRKLEFLKSQSEAVEKQIATKNLRQIA Treme1 I-DITDLQLQEVKKQLDAELDHLTNSYSQLKQAQAKFKACVNDIKEILVPLTSSLYVPGKI-NDPEYVVVDVGTGYYVRKYTSKSNFVQQNLETLQKAIEKKQVVGVL Trire2 V-NLDTLQLAQVKKQLEEELEHLTSSFAQLHGAQNKFKECLRCVKSVLVPLTNSLYVSGEL-TSTETVLVDVGTGFMIEKYDSKVKEVGGNLKELEVIVQRKQIEE-- Umbra1 I-DLGDLQLQQVKSQLEEELSHLTQSYSQLRGAQARFNDCKDSVKTILVPLTSSLYVPGKL-SNVETVIVDVGTGYFVEKYKEKIDYVKASAAKLQETITSKQLVNVM Ustma22 V-DLMSLQLLEVKKQLETEVQHLTSSFGQLKAAQAKFKSCIESVKTTLIPLTSSLYVPGKL-SDLEKVIVDVGTGYFVEKYQEKVEFLTKNLEQLQETVLRQQTVEMI Walse1 I-DVSQLQLSGVKKQIDEELSHLTQSYAQLRRAMIQFKQSASAVKKVLVPLTTSLYVPGKL-TDVENVLVDIGTGYYVKKYKSKVDYVNKNLETLQQTLEKKQVVQIM Zygro1 I-DLTKLQLAAVKQQIDQEFQHFNQSLQALTLARNRFQDCIEDIQKIMVPASASLYIPGKI-VENDKFMVDVGTGYYVEKYEHKIQKLNKESVQIQNIIKEKTIEAHI [Cluster1912.fasta_al_trimmed; alignment length = 132] Allma1 SSMFFQYNEALGPPYHVIVDTNFINFSIQNKLDPMMDCLYAKCIVCIPDCVVAEIEKLGIKYRLALKTARDPRFERLPCHKGTYADDCIVNRVTQHKCYIVATCDKELKRRIRKIPGIPIMYIKYQIERLPD Ashgo11 SALFFQYNQAIKPPYQVLIDTNFINFSIQKKIDLMMDCLLAKCVPLITDCVMAELEKLGPKYRIALKLARDPRIKRLNCHKGTYADDCLVNRVLQHKCYIVATNDAGLKQRIRKVPGIPLMSVSYVIEKLPD Aspfu1 SNMFFAANTALGPPYTVLVDTNFVSHTIRAKLDMMMDLLYAKCIPTFTDCTIAELEKLGPKFRLALRVAKDPRWNRLHCHAGTYADDCIVDRVMKHRIYTVATNDKDLVRRIRKIPGVPIMKVKYVIERLPD Aurde31 SSLFLQHNEALAPPYRVLIDTNFINFSLQNKIELMMDCLYAKCIPCVTDCVMAELEKLGPRFRIALRVARDPRFERLPCHPGTYADDCLIQRITAHRCYIVATCDRELRRRVRKVPGVPLMYIKYAIERLPD Batde5 SSLFFQHNEALIPPYHVIVDTNFINFSIQNKLEIMMDCLLAKCVPCITDCVMAELEKMGLKYRLALKVARDPRFERLPCHKGTYADDCIVNRIMQHKCYIVATCDKDLKRRIRKVPGVPIMYIKFAIERLPE Botbo1 SSLFLSHNTALAPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGPKYRIALRVARDPRFERLPCHQGTYADDCLVQRVTASKCYIVATCDRELRRRIRKVPGVPLMYIKYAIERLPD Botci1 SALFFQYNEALVPPYSILVDTNFLSHTVQRKLPLLMDCLYAKCIPIITSCVMAELEKLGPRYRIALRIARDERWQRLQCHKGVYADDCIVDRVQKHKIYIVATNDRELKRRIRKVPGVPIMSVKYVIERLPD Caeel SAMFMKYNTQLGPPFHVIVDTNFVNFAVKNRIDMFMDCLFAKTIVYATDCVLAELEKV-RRFKIALKVLKDPRVQRLKCHKGTYADDCLVQRVTQHKCYIVATCDRDLKRRIRKIPGVPIMYIRFSIERMPD Canalb1 SALFFKYNESIKPPYQVLIDTNFINFSIQKKIDILMDCLMAKCIPIITDCVIAELEKLGSKYRIALKLAKDPRIQRLKCHVGTYADDCLVNRVIQHKCYIVATNDADLKRRIRKIPGIPIMSVSYVIERLPD Cangl SALFFQYNEAIKPPYQVLIDTNFINFSIQKKIDIMMDCLLAKCNPLITDCVIAELEKLGPKYRIALKLARDPRIKRLTCHKGTYADDCIVNRVLQHKCYIVATNDAGLKQRVRKIPGIPLMSVAYVIEKLPD Capow SALFFKYNTQLGPPYRILLDTNFINFSIQNKLEVAMDCLFAKCIPCVTDCVMAELEKLGLKYRLALKVAKDPRFERLPCHKGTYADDCLVQRVTQHKCYIVATCDRDLKRRIRKVPGVPIMFIRYSIERMPD Catan2 SSLFFKYNEALGPPYHIIIDTNFINFSIQNKLEVMMDCLFAKCIVCVPECVIAEIEKLGVKYRLALKTARDPRFERLPCHKGTYADDCIVNRVTQHRCYIVATCDKGLKQRLRKIPGVPIMSIKYAIERLPD Cioin SALFFKYNEQLGPPYHILVDTNFINFSIKNKLEMMMDCLYAKCIPCITDCVMAELEKLGPKFRVALRIAKDPRFDRLPCHKGTYADDCLVQRVTQHKCYIVATCDRDLKRRIRKIPGVPIMYLKYTIERMPD CocheC53 SALFFQANTALGPPYSVLVDTNFLSHTVHAKLELLMDLLYAKATPIITTCVMAELEKLGPKYRIALRIARDERWQRLKCHKGTYADDCIVDRVQKHRIYLVATNDRDLKRRIRKIPGVPIVSVKYVIERLPD Coere1 SNMFFKYNTSLGPPYHIIVDTNFINFALQNRLDLMMDCLYAKCVPCITDCVLAELEKLGPKYRMALRVARDPRFERLPCHKGTYADDCIVKRVMQHRCYIVATCDRDLKRRIRKVPGVPIMFIKLSIERLPD Conco1 ------------------------------------------------------------------------------------------------------------------------------------ Conpu1 SSLFLAHNTELVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGHRYRVALRVARDPRFERLNCHTGTYADDCLVQRVTAHKCYIVATCDRELRRRIRKIPGVPLMYIRYAIERLPD Copci SSLFLQHNTALVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGHKYRVALRVARDPRFERLRCHTGTYADDCLVQRVTSHKCYIVATCDRDLRRRIRQIPGVPLMYIRYAIERLPD Croqu1 TSLFLTHNTALAPPYRVLVDTNFLNLSIINRIDLMLDCLYAKAIPCISDCVIAELEKLGTKYRLALNLSKDPRVERLPCHKGTYADDCIVQRVNSHRCYIVATCDRGLRRRLRKIPGVPLMFIQYAIERLPD CryneH991 SSLFLSHNTDLGPPYRILVDTNFINFSIQNKIELMMDCLMAKCIPTITDCVLAELEKLGPKYRLALKIAKDPRFERLHCHNGTYADDCLVQRVTVHKCYIVATCDRDLRRRIRKVPGVPLMYVRYQIERLPE Crypa2 SSMFFQHNTALVPPYQVLVDTNFLSHTVSRKIELMMDALYAKCEVLITSCVMAELEKLGPKYRIALRIARDERWKRLPCHSGTYADDCIVDRCMKHRIYIVATNDRDLKRRLRKIPGVPIMSVKYVIERLPD Debha1 SSLFFQFNKSIKPPYQILIDTNFINFSIQKKIDIMMDTLFAKCIPMITDCVMAELEKLGPKYRIALKLAKDPRIQRLSCHKGTYADDCLVNRVIQHKCYIVATNDADLKRRIRKVPGVPIMSVAYVIERLPD Dekbr2 SALFFQYNEAIKPPYQILLDTNFFNFSIQKKIDIMMDCLYAKCIPMVTDCVVAELEKLGPRYRIALTLAKDPRIKRLTCHKGTYADDCLVHRVMEHKCYIVATNDADLKRRIRKVPGIPIMSVSYVIERLPD Dicdi SHMFFSYNEALVPPYHVIIDTNFINFSISHKLDILMDCLYAKCIPYISDCVAAEIERLGSKFKVALKISKDPRFQRLTCHKGTYADDCIINRITMHRMFIVATCDADLRRRIRKIPGVPIVYLKYTVERMPD Dmel SALFFQYNTQLGPPYHIVLDTNFINFSIKNKLDIMMDCLYAKCIPYISDCVRAELEKLGNKYKLALRIISDPRFERLPCHKGTYADDCLVERVRQHKCYIVATNDKDLKNRIRKIPGVPIMYVKYAIERMPE Enthi SYKYFADNPNLGPPYHLLLDTNFIQFSIGKKVDIAMRCLLAKVIPCITDCVMAELELLGKKFQMALKIARDPRFKRLTCHKGHYGDDCIVQRVTAHRIYIVCTCDKDLKRRLRKIPGVPLMTVKFDIEKLPR Falba TGLFFRYNTALGPPYRVLVDTNFINFSIQNKLELMMDCLYAKSIPCITDCVMAEIEKLGSRFRVALRVAKDPRFERIACHKGTYADDCLVERVTQHPCYIVATCDRDLRRRLRKVPGVPIMYIRYSVERMPE Fomme1 SSLFLQHNTALSPPYRVLIDTNFINFSLQNKLDLMMDCLYAKCIPCVTDCVLAELEKLGPRYRIALRIARDPRFERLACHQGTYADDCLVQRVTASRCYIVATCDRELRRRIRKVPGVPLMYIRYAIERLPD Fusgr1 SNMFFQHNTALVPPYSVLVDTNFLSHSVQRKLSLMMDCLYAKCNPIITSCVMAELEKLGPKYRLALRVARDERWTRLECHKGVYADDCLVDRVQKDRIYIVGTNDKALKQRLRKIPGVPIMSVKYVIERLPG Galma1 SSLFLQHNTALVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCITDCVMAELEKLGHRYRVALRVARDPRFERLRCHTGTYADDCLVQRVTAHKCYIVATCDRELRRRIRQIPGVPLMYIRYAIERLPD Ganpr1 SSMFFKYNTSLTPPYNVLIDTNFINFSISNKLDIMMDCLFAKCVPCVTECVLGELEKLGPKYRLALMTARDPRFEKLPCHKGTYADDCLVERVMQHKCYIVATCDRDLKRRIRKVPGIPIMYIKYAIERLPD Gloin1 SSLFFRYNTALGPPYRVMVDTNFINFSIQNKLELMMDCLYAKCIPCITDCVMAELEKLGPKYRIALRVARDPRFERLPCHKGTYADDCLVQRVSQHKCYIVATCDRDLKRRIRKIPGIPIMYIRYTIERLPE Hisca1 SALFFQYNTALTPPYSILVDTNFLSHTVQHKLDVMMDCLYAKCIPLVTDCVLAELEKLGPKYRIALRIAKDPRFERLKCHKGTYADDCLVDRVIKHRVYIVATNDRDLKRRIRKIPGVPIMSVKYVIERLPD Klula1 SALFFQYNEAIKPPYQVLIDTNFINFSIQKKIDIMMDCLLAKCNILITDCVMAELEKLGPKYRIALKLARDPRIKRLSCHKGTYADDCIVHRVLQHKCYIVATNDAGLKQRVRKVPGIPLMSVSYVIEKLPG Lacbi2 SSLFLAHNTALVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGHRYRVALRVARDTRFERLRCHTGTYADDCLVQRVTAHKCYIVATCDRELRRRIRQIPGVPLMYIRYAIERLPD Lenti61 SSLFLQHNTALVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGHRYRVALRVARDPRFERLACHSGTYADDCLVQRVTSHKCYIVATCDRELRRRIRKIPGVPLMYIRYAIERLPD Malgl1 SSMFFQHNSALGPPYRVLVDTNFINFSLQNKIELMMDCLYAKTIPCITTCVLSELEKLGPKYRIALRVARDPRFERLECHKGTYADDCIIERIKSHKCYIVATCDRELRRRVRQVPGIPLMYIRYRIERLPD Mellp23 TSLFLTHNTALAPPYRVLVDTNFLNLSLTNRIDLMLDCLYAKAIPCVSDCVIAELEKLGTRYRLALNLARDPRVERLPCHKGTYADDCIVQRVTAHRCYIVATCDRGLRRRLRKIPGVPLMFIQYAIERLPD Mnele SALFFKYNTQLGPPYHVLIDTNFINFSIRNKLDIMLDCLYAKCTPYITDCVMAELEKLGAKYRVALRIAKDPRIERLICHKGTYADDCLVQRVQEHKCYIVATNDKDLRRRIRKIPGVPIMFVRYSIERMPD Monbr --MYFSYNTQLGPPYHILIDTNFINFSIQNKLDISMNCLYAKTIPCITDCVMAELEKLGRKYRVALRMAKDERFKRLPCHKGTYADDCLVERVSQHKCYIVATCDRDLKRRIRKVPGVPIMYIKYTIERMPD Morel2 SSMFFNYNSALGPPYRILVDTNFINFSIQNKIELMMDCLYAKSIPCITDCVMAELEKLGPKFKVALRVARDPRFERLPCHKGTYADDCLVERVMQHKCYIVATCDRDLKRRIRKIPGIPIMYLKYTIERLPE Mucci2 SSMFFQYNAALGPPYHILVDTNFINFSIQNKLELMMDCLYAKSVPCITDCVLAELEKLGPKYRIALKIARDPRFERLPCHKGTYADDCLVNRVMQHKCYIVATCDRDLKRRIRKVPGIPIMYIKYVIERLPE Mydma SALFFQYNTQLGPPYRVIVDTNFINFSIQNKLDIMIDCLYAKCIPYITDCVMGELEKLGSHYRVALRVAKDERFERLPCHAGTYADDCIINRITQHKCYIVATCDRDLKRRIRKVPGVPIMYLRFTIERMPD Neucr2 SSMFFQHNEALVPPYNVLVDTNFLSRTVGAKLPLAMDCLFASVNIIITSCVMAELEKLGPKYRVALMIARDERWTRLTCHKGTYADDCIVERIQKHRIYIVATNDRDLKRRIRKVPGVPIMSCKYAIERLPG Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------ Pench1 SSMFFQFNTALAPPYSVLVDTNFISHTIQHKLEVMLDCLYAKCIPIVTDCVLAELEKLGPKYRLALRVAKDPRFERVKCHKGTYADDCLVDRVIKHRVYIIATNDRDLKRRIRKIPGAPIMSVKYVIERLPD Phybl2 SSMFFQYNAALGPPYHVLVDTNFINFSIQNKLELMMDCLYAKSIPCITDCVMAELEKLGPKYRIALKIARDPRFERLPCHKGTYADDCLVQRIMQHRCYIVATCDRDLKRRIRKVPGIPIMYIKYVIERLPE Picst3 SALFFKFNLAIRPPYQVLIDTNFINFSIQKKVDILMDCLMAKAIPIVTDCVMAELEKLGPKYRIALKLAKDHRIQRLSCHGGTYADDCIVNRVMQHKCYIVATNDADLKRRVRKVPGVPLMSVAYVIERLPD Plicr1 SSLFLAHNASLVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVMAELEKLGHRYRVALRIARDPRFERLACHTGTYADDCLVQRVTAHKCYIVATCDRELRRRVRKIPGVPLMYIRYAIERLPD Polpo HHMFFSFNEALVPPYHVIIDTNFINFSISNKIDILMDCLYAKCIPCITDCCAAELERLGPKYRIALKVSKDPRFQRLTCHKGTYADDCIINRITMHRIYMVATCDADLRRRIRKVPGVPILYLRYTIERMPD Pucgr2 TSMFLTHNTALAPPYRVLVDTNFLNLSLTNRIDLMLDCLYAKAIPCVSDCVLAELEKLGTRYRLALNLARDPRVERLPCHRGTYADDCIVQRVTAHRCYIVATCDRGLRRRLRKIPGVPLMFIQYAIERLPD Punst1 SSLFLQHNTSLAPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPCVTDCVLAELEKLGSKYRVALRVARDPRFERLNCHSGTYADDCLVQRVTSHRCYIVATCDRDLRRRLRKIPGVPLMYIRYAIERLPD Rhior3 SSMFFEYNTSLGPPYHVLVDTNFINFSIQNKLELMMDCLYAKSIPCITDCVLAELEKLGPKYRIALKIARDPRFERLPCHKGTYADDCLVDRVMQHKCYMVATCDRDLKRRIRKIPGIPIMYIKYVIERLPE Rhoto1 TSLFFSHNEALVPPYRVIVDTNFINLSLENRVDIMMDVLYAKAIPCISDCVLAELEKLGHQYRLALRVARDPRFERLPCHKGTYADDCIVNRVTQHRCYIVATCDRQLRRRLRKVPGVPLMYIRYAIERLPD Rozal11 SSLFFRYNQSLGPPYHIILDTNFINMAIQNKLEIMMDCLYAKCIPCITDCVLAEIEKLGSKFRVALTIARDPRFKRLKCHEGTYADDCIVQRVTQHKCYIVATHDKALKKRIRQIPGVPIMYVKVMVEQLPE Sacce1 SALFFQYNQAIKPPYQVLIDTNFINFSIQKKVDIMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCHKGTYADDCLVHRVLQHKCYIVATNDAGLKQRIRKIPGIPLMSVAYVIEKLPD Salro SALYFHYNTQLGPPYHILIDTNFINFALQNKLDISMDCLFAKCIPCITDCVMAELEKLGRKYRIALKVAKDPRFKRLPCHKGTYADDCLVNRVSQHKCYIVATCDRDLKRRIRKIPGVPIMFIKFTIERLPD Schco3 SSLFLAHNTALVPPYRVLIDTNFINFSLQNKLELMMDCLYAKCIPVVTDCVMAELEKLGHRYRVALRVARDPRFERLKCHSGTYADDCLVQRVTAHKCYIVATCDRELRRRIRQIPGVPLMYIRYAIERLPD Schpo1 SNLFFQFNESLGPPYHVIIDTNFINFCLQQKIDLLMTCLYAKTIPCISDCVMAELEKLGIRYRIALRIAKDERFERLPCHKGTYADDCIVQRVMQHKCYLVATNDKNLKQRIRKIPGIPILSVKIRVERLVD Sorma SSMFFQHNEALVPPYNVLVDTNFLSRTVGAKLPLAMDCLFASVNIIITSCVMAELEKLGPKYRVALMIARDERWTRLTCHKGTYADDCIVERIQKHRIYIVATNDRDLKRRIRKVPGVPIMSCKYAIERLPG Sphar TALFFHYNQSLGPPFHILLDTNFINFSIQNKMEIAMDCLYAKCVPCITDCVLAELEKLGSKYRVALRIAKDPRFKKLRCHKGTYADDCLVDRVMQHKCFIVATCDKDLKRRLRKVPGVPIMGIKYNVERMPD Spipu1 SSLFFKYNEALGPPYHVLVDTNFINFSIQNKLELMMDCLYAKCIPCITDCVMAELEKLGVKYRIALKIARDPRFERLPCHKGVYADDCIVNRVMQHKCYIVATCDRELKRRIRKIPGIPIMYIKYAIERLPD Sporo1 TSLFFAHNEALVPPYRVIIDTNFINLSLENRIDLMMDVLYAKAIPCISDCVLAELEKLGQKYRLALRVARDPRFERLPCHKGTYADDCIVNRVTQHRCYIVATCDRQLRRRLRKVPGVPLMYIRYAIERLPD Stehi1 SSLFFSHNTALVPPYRVLVDTNFINFSLQNKLELMMDCLYAKCIPCITDCVMAELEKLGPKYRVALRIARDPRFERLACHRGTYADDCLINRITASKAYIVATCDRELRRRVRRVPGVPLMYIRYAIERLPD Tapde11 SSLFFQFNEALRPPYRVLIDTNFINFCIKNKLDLMMDALYAKCIPCITDCVLAELETLGSKFRLALQVAKDPRFERLTCHKGIYADDCLVDRCMQSRCYLVASNDLHLKQRIRKIPGVPILYVVIKVERLPD Thetr SALFFSFNQQLKPPYSILLDTNMLAHSVHTKLDIMMDCLHAKVVPMITDCVMAELEKLGPKYRVALRLAKDPRFKRLVCHKGTYADDCLVRRVMAHKCYLVATQDRDLKRRIRKIPGVPIIYIKYCVERMPD Treme1 SSLFLSHNTDLGPPYRVLVDTNFINFSIQNKVELMMDCLMAKCIPTITDCVLAELEKLGPKYRLALRIAKDPRFDRLHCHSGSYADDCLVQRVSVQKCYIVATCDRDLRRRIRKVPGVPLMYVRYQIERLPD Trire2 SGMYFAHNTNISPPYNVLVDTNFLSHTVQRKLSLMMDCLYAKCNPIITSCVMAELEKLGTKYRLALKIARDERWQRIQCHKGTYADDCIVDRVTKDRIYIVGTNDKALKQRLRKIPGVPIMSVKYVIERLPG Umbra1 SSLFFKYNSALGPPYHVLVDTNFINFSIQNKLELMMDCLLAKSIPCITDCVLAELEKLGPKYRIALKIARDPRFERLPCHKGTYADDCLVQRIMQHKCYIVATCDRDLKRRIRKVPGIPIMYIKYVIERLPE Ustma22 SSMFFEHNTQLGPPYRVLVDTNFINFALQNKIELMMDCLYAKSIPCITSCVISELEKLGPKYRIALRVARDPRFERLECHKGTYADDCIIERITSHKCYIVATCDRELRRRVRKVPGIPLMYIQFRIERLPD Walse1 HSLFFSHNEALAPPYHVLVDTNFINFSLQNKLDLMMDCLFAKCIPCISDCVIAELEKLGTKYRMALRVAKDPRFLRLPCHTGTYADDCIVQRIQAHKCYIVATCDRELRRRVRKVPGIPLMYIRYAIERLPD Zygro1 SALFFQYNQAIRPPYQVLIDTNFINFSIQKKIDIMMDCLLAKCNPLITDCVMAELEKLGPKYRIALKLARDPRIKRLSCHKGTYADDCLVNRVMQHKCYIVATNDAPLKQRVRKIPGIPLMSVSYVIEKLPD [Cluster1915.fasta_al_trimmed; alignment length = 258] Allma1 RMYEAKFPEVDELVMVNVRQIQ--EMGAIVHLLEYNDIEGMILLSELSRRRIRSIQ--KLIRVGRNEIALVLRVDKEKG--YIDLSKRRVAPEDIAKCEEKFNKSKAVHSIMRHVAEKLNELYEQFGWPLYK--KFGHAYEAFKLAIAEPEKVFEGLIKRRMTPQPVKIRADVEVTCFGIDAIKTALQTCEAQSTDIKVRLVAPPLYVITTDKNSGIEKLEAAIQVMIKMKPRAVSATDEELAELMERVERENAEVSG Ashgo11 RFYENKYPEVDDVVMVNVQQIA--EMGAYVKLLEYDNIEGMVLLSELSRRRIRSIQ--KLIRVGKNEVVVVLRVDKEKG--YIDLSKRRVSSEDMIKCEERYQKSKAVHSILRQCAEKLEDLYKTIAWPLSR--KYGHAYDAFKLSIVDET-VWEGIISRRLTPQAIKIRADVEVSCFGIEAIKEALKAAEATSTEVKVKLVAAPLYVITTDKNQGIEALNHAISKIVTMPPKAVTATEDELQALLESKELENRSDSE Aspfu1 RFYEEKYPEVDSYVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRIGRNEVVIVLRVDKEKGKCYIDLSKRRVSPEDVVKCEERYNKSKAVHSIMRHVAEALEELYQKIGWPLNR--KYGHAHDAFKISITNPD-VWQDVISKKLTPSPTKVRADIEVTCFGIDAVKNALRTAEANNTPIKVKLVAPPLYVLTSDKNLGIKLLEEAIERIVKMAPKAVTEHDDALQELMDKRERENMEVSG Aurde31 RYYEQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYTKSKTVASIMRHVASKLETLYEQIAWPLAK--KYGHTYDAFKLALTEPDAVFEGLIARRLTPQPIKMRADVELSCFGIDAIKRALRAGEAVSTDIRAKLVAPPLYVLTTDKYGAVDRLERAIEIIVKMKPKAVSESEEDLANLMQKASKENAEVSG Batde5 -MYEDRYPEVDSLVMVNVRQIA--EMGAYVHLLEYNNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEEVAKCEERYNKSKSVHGIVRHVAEKLEDLYTQVIWPLYK--KFGHAYEVFKLALTEPETIFADFIRRRLTPQAIKIRADIECTCFGIDAIKAALLAGEACSTAIKIKLVAPPLYVMITEKVEGVETMERAITTIVKMKPRAVSETDDELAQLMAKMERENAEISG Botbo1 RYYSQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIAKCEEKYMKSKTVASIMRHVSSKLEQLYEQIAWPLGR--KYEHPYDAFKLALTEPDAVFEGLIARRLTPQPIKLRADIELTCFGIDAIKKALKAGEAVSTLVKAKLVAPPFYVLGTDKHAGVDKLEAAIDAIVRMKPKAVSETEDELAALMARAGQENAEVSG Botci1 RFYEEKYPEIDSFVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVRCEERYNKGKMVHSIMRHVAEKIEELYEKIVWPLNK--KYGHAVDAFKLSITNAE-TWNDVIGKRLTPQPTKVRADVEVTCFGIDAVKTALRTAEARNTAVKVKLVSPPLYVLTSEKSVGISTLEAAIVDIVKMEPKAVTENDDELQALMEKRERENAEVSG Caeel RFYENQFPDVEETVVANVKMIA--DMGAYVRLSEYNDKEGMILLSELSRRRIRSVN--KLIRVGRSESVVVIRVDKDKG--YIDLSKRRVYQKDLKQCDERFANAKMVNSILRHVAEQLEDLYQKTAWHFDR--KEAASYDAFKKAITEPT-ILDECIRKKLTPQAVKIRADIEVSCFGIDAVKAALIAGKNCSNGIKINLIAAPHFVVTTDREGGIEAVNSILDTIIKEEARIVTDIDDDQQVDAEEASRDNRKKAG Canalb1 RFYENKYPEVDEVVMVNVQEIA--EMGAYVKLLEYDNIEGMVLLSELSRRRIRSIQ--KLIRVGKNEVAVVLRVDKEKG--YIDLSKKVVSAEDIVKCDERYNKSKAVHSILRHCAEKLERLYETIGWPLSR--KYGHAYDAFKISITDPS-VFDSVISRRLTPQAINIRADVDVSCFGIDAIKEALKAAESVSTSVKAKLVAAPLYFITVDKNEGVKLLEKAIEKIVSMPPKAVSANEDELERMLQRREAEDKDSSD Cangl RFYENKYPDVDDVVMVNVQQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGKNDVAVVLRVDKEKG--YIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKLEDLYKTIAWPLSR--KFGHAYEAFKLSIIDET-VWEGIISKRLTPQAVKIRADVEVSCFGIDAIKEALKSAEDMSTEIKVKLVAAPLYVLTTDKQIGIDLLGKAIDKIITMPPKAVTATEDELQALLESKEQDNRSDSE Capow RFYEQPFPEVDDVVVVNVRSIA--EMGAYVNLLEYNNIEGMILLSELSRRRIRSVNKLKLIRVGKSECVVVLRVDRDNS--YIDLSKRRVSAEEIRKAEEKFNKAKTVNNLLRYVAEVLEELYKQTAWELDK--RFGSCYEAFKLAISDPDLIFKDLIRRKLAPQQMRIRADIEVACYGIDAVKNALRAGLAVSTEVKINLIAPPLYVMTTDREKGIKALSNAIEAIVQNEPRAVTETDDQLAELMEDYARRQTERPG Catan2 RMYEAKFPELEDLVMVNVRQIA--DMGAYVRLLEYDDIEGMILLSELSRRRIRSVQ--KLIRVGRNEIALVLRVDKEKG--YIDLSKRRVTPEDLVKCEEKFNKSKAVHSIMRHVAEKLQDLYEQFGWPLYR--KYGHAFDAFKLAIQDPEKVFEGLIRRRMTPQPVKIRADVEVTCYGIDAIKTALGQCEGLSTEIKVRLVAPPLYVITTDKQGGIDLLERAIATIIKMKPRAVSATDEELAELMERFERENAEVSG Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 RFYEEKYPEVESFVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKDKG--YIDLSKRRVSPEDIVKCEERYNKSKMVHSIMRHVAEKIEEIYQTIGWPLNK--KYGHSIDAFKLSITNPE-VWNDVIGKRLTPQPTKVRSDIEVTCFGIDAVKEALRCAEAKNTPVKVKLVSPPLYVLTSDKNAGIACLEQAILDIVKMAPKAVTENDDELAALMEKRERENQEVSG Coere1 RFYKAKYPSPGEVVIATIARISDDEIGAYVQLDEYGGIEGMIPLSELSRRRIRSVQ--KLLRVGKREPMAVLRVDQDKG--YIDLSKKTVSVEEAQACEEKFKMSRKVHTIVTHVAKKPEALYEQFGWPLYE--KYGHACDAFKAAVANPDAVFGEFILRHMKPQRAKLHAKIDVRCFGIEAIRRALTAAQNISTELSIRLIAPPEYVISTNADEDIELMNKAIEAAVLVSPRQVTEHEEELRDLMDRAERENKEVSG Conco1 RMYENQFPEVEDVVMVNVKQVQ--DVGVYVQLLEYDNIEGMIQLSELSRRRIRSMQ--KLIRVGRNEVVVVLRVDQDKG--YIDLSKRRVTPEDYVKCEEKFNRSKAVHGIMRHVAEKLEDLYKQFGWPLYK--KYGHAYDAFRLAITDPDTVFEGLIRHKLTPQPAKFRADIDVTCFGIDTIKAALKVGEALSNEIKIKLVAPPSYVMITDKTEGVEILERAIEAMVKMQPKAVSETDEELADLMSRMEKENAEVSG Conpu1 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDREKG--YIDLSKRRVSPEDITKCEERYNKSKAVASIMRHVASKLEKLYEQIAWPLGH--KYGHPYDAFKVALTEQESVFSSLIARRLTPQPIKLRADIELTCYGIDAIKKALRAGEKESNDIKAKLVAPPLYVLSTDKYAAVDRLERAIESIVKMKPKAVSETEEDLAQLMAKAGQENAEVSG Copci RYYEQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNTEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYMKSRAVASILRHVASKLEHLYETIAWPLGK--IYGHPYDAFKLALTEPDVVFSSLIAKRLTPQPIKLRADIELTCYGIGAIKKALRAGEKQSTEIKAKLVAPPLYVLSTDKYAAVDRLEKSIEAILKMKPKAVSETEEDLANLMLKAGQENAEVSG Croqu1 RYYRPKFPEPDELVMVQVKQIQ--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVMRVDKEKG--YIDLSKRRVSAEDVVKCEERYNKSKTVSSIVRHVAEKLEAVNEMIAWPLFE--KYGHAFDAFKLSITEPETVFGELIARRLTPQPVKVRADLEATCFGIDAIRNALKLGESMGTEIKIRLVAPPLYVMVSDKQGAIELLETAIERIVKMKPKAVSETDDELAALMERVARENKEVSG CryneH991 RFYENKYPEVDQLVMVQVQSIE--DMGAYVKLLEYDNIEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVMRVDPDKG--YIDLSKRRVSAEEVVKCEEQYEKGKAVDSIITQVAKKPESLYEKIAWPLHR--QYGHAYEAFKLSISEPDAVFGTLIARRLTPKPVKVRADVEVKCFGIEAIKRALTAGEAVSTPIKVRLVAPPLYVMSTDKNAAIELMEKAVEVIIKMKPKVVSETEDELKALMEQFEAANMDQAG Crypa2 ---------------------------------------------------------------------------------------------------------------MRHVAEKIEELYESIAWPLNR--KYGHAIDAFKLSITNPD-VWTDIISKRLTPQPTKLRADIEVTCFGIDAIKTALSRAEANNTDIKVRLVSPPLYVLTSDKSSGIARLEQAIADVVKMEPKAVTESDDELQALMEKRERENAEVSG Debha1 RFYENKYPEVDEVVMVNVQEIA--EMGAYVKLLEYDNIEGMVLLSELSRRRIRSIQ--KLIRVGKNEVAVVLRVDKEKG--YIDLSKRRVSAEDIVKCDERYNKSKAVHSILRHCAEKLETLYQSIGWPLSR--RYGHAYDALKLSITDPT-IFDDIISRRLTPQAIKIRADVEVSCFGIDAIKKALTAAEEISTEVKAKLVAAPLYVISVDKNQGIALLEKAIEKVVTMSPKAVTATEDELQALLERKEAEDKESSD Dekbr2 RFYENKFPEVEEVVMVNVLQIA--EMGAYVKLLEYDNIEGMVLLSELSRRRIRSIQ--KLIRVGRNEVAVVLRVDKEKG--YIDLSKRRVSAEDIVQCEERYNKSKAVHSILRRCAEKLETLYKTIAWPLAK--EYGHAFDAFRLSISKPS-IFDTIIARRLTPQAVKCRADIDVSCFGIDAIKEALKAGESVPTSITIKLVAAPRYVMTTDKKQGVEELQKSINKIVAMAPKSVSASEDELQALLERNEMESSLDSD Dicdi RMYEKKYPEENELVMVRIESIG--DMGVYVSLLEYNNIEGMILLSEISRRRIRSIN--KLVRVGKTEAVVVVRVDKDKG--YIDLSKRRVTPEEYAQCEERFHKSKAVHGIVRYVATKTKHLYTKFVWPLYT--KYGHAYEAFKLSITEPS-VFNGFIIQKLKPQPHKVRADLEITCYGIDAIKHAITASQNHALSVTIKLVAPPLYVMVGEKEKGLSMVGQCVDVLIKAAPRIVGAVDDELRDLMEQLEVENQDGDG Dmel RFYNERYPEIEDVVMVNVLSIA--EMGAYVHLLEYNNIEGMILLSELSRRRIRSIN--KLIRVGKTEPVVVIRVDKEKG--YIDLSKRRVSPEDVEKCTERFAKAKAINSLLRHVADILEDLYQKTAWHFEK--KYTVAYDIFKQSVTDPT-VFDECIKRKLVSPTVKIRADIECSCYGIDAVKASLTKGLELSTEIRINLIAPPLYVMTTKKTDGLKALEVAIEHIVIMAPKLVTAIDEDLARRLERAEAENAQVAG Enthi RMLEQKFPNEDDLCLVTVVSSS--EMGTYVALKEYDDIQGMIPMSELSRKRYKQT---RLTRVGKEEVATVIRVNSESG--FIDLSLKRTTPEEKSAFLTKYTKNKEAHLIMRLIAKKMEELYTMFGWPLAK--KYGTLHDAFRKSLTEPD-VFEPYISHYMTIQPLKFRADIEVSCFGVESVKRALLKGVESAGDLVIKLVSSPLYVLFLERQKGMEIMYAAVAAIVKRDPCVVSKEEE----------EENEDTTE Falba RMYQNKYPAVDDLVMVNVRQIA--DMGAYVELLEYDNREGMILLSELSRRRIRSVQ--KLVRVGRREVVVVLRVDQDKG--YIDLSKRRVTPEDVVKCEERYNKSKEVHSILRHVAEKLESLYELIGWPLYT--THGHAYDAFKMAILEPSIITEAFVGRRMTPQPVKLRADLDLTCFGIDAIIEAIKIGERESTQIKIKLIAAPMYVMTANKNEGIRLMEEAITKMIRMRPRAINVEDEQLAELMLAAEKEQADT-- Fomme1 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDREKG--YIDLSKRRVSPEDIVKCEERFMKSKTVASILRHVASKLEALYEQVAWPLGK--IYSHPYDAFKLALTEPEKVFGQLIARRLTPQPIKLRADIELTCYGIDAIKRALRAGEKASTEIKAKLVAPPLYVLATDKYAATERLERAIETIVKMKPKAVSETDEELSQLMAKASAENAEVSG Fusgr1 RFYEEKYPEIDSFVMVNVKQIA--EMGAYVKLLEYDDIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYNKSKMVHSVMIHLAKALETLYQAIAWPLNK--KFGHALDAFKLSITNPE-VWNDIIGKRLTPQPTKVRADVEVTCFGIDAIKTALHTAEAKNTEVKVRLVSPPLYVLNSDKSLGITRLQEAIVDIVKMEPKAVTESDDELQALMEKRERENAEVSG Galma1 RYYEQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNTEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYLKSKTVASILRHVASKLEQLYDQVAWPLGK--KYGHPYDAFKLALTEPDTVFSSLIARRLTPQPIKLRADIELTCYGIDAIKKALRKGEKQSSEIKAKLVAPPLYVLSTDKYAAVERLERAIEAIVKMKPKAVSETEEDLAQLMMKAGQENAEVSG Ganpr1 -MYENQYPQIDELVIATVRKIE--SLGVYVTLPEYNNVEGMIPLSELSRKRIRSMA--SLIRVGRSEAVMVLRVDDERG--YIDLSKRRVQPEEIGKAEERFLKSKMVQSMMRQVAEHLEEIHRAVTWPLNK--KYGHALDGFKIAMIDPDRALEGLVRRRLTPQAVKLRADIEVTCFGIDAVKKALFAGEAVSTEIRTRLVAPPLYVMTTDKVAGIKLMEESILAMVKMMPRAVSETDDELERLMERAEQETKEVGG Gloin1 RMYEERFPEKEDLVMVNVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKDKG--YIDLSKRRVSPEDVAKAEEKFNKSKAVHSIMRHVAEKLEDLYQKIGWPLYK--KYGHAYEAFKLAITEPEKVFEGLIKRRLTPQPIKIRADIEVTCFGIDAIKSALKAGEACETGIKVKLVAPPLYVMITDKNMGIELLGKAIETVVKMKPRAVSETDDELAALMARVEKENAEVSG Hisca1 RFYEEKFPEIDSFVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDVIKCEERYNKGKLVHSIMRHVAEKMETLYSQIGWPLNK--KYGHSIDAFKLSITNPS-VWDDVISKKLTPHPTKVRADVEVTCFGIDAVKDALRTAESNNTQVKVKLVSPPLYVLTSDKNHGISVLEEAIKSIVKMAPKAVTEHDDELQALMEKRERENQEVSG Klula1 RFYENKFPEVDDVVMVNVQQIA--EMGAYVRLLEYDNIEGMVLLSELSRRRIRSIQ--KLIRVGKNEVVVVLRVDKEKG--YIDLSKRRVSAEDVIKCEERYQKSKAVHSILRQCAEKLEDLYKAYAWPLSR--KYGHAYDAYKMSIVDPN-VWDGIITRRLTPQAVKIRADVEVSCFGIDAIKEALKSAEELSTEIKVKLVAAPLYVITTDKDQGVQLLETAIAKIVTMAPKAVTATEDELQALLESKELEGRSDSE Lacbi2 RYYEQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNTEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYMKSKTVASILRHVASKLEQLYDLIAWPLGK--KYGHPYDAFKLALTEPDAVFSSLIARRLTPQPIKLRADIELTCYGIDAIKKALRAGEKQSNEIKAKLVAPPLYVLSTDKYAATERLERAIEAILKMKPKAVSETDESLAELMVKAGQENAEVSG Lenti61 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDITKCEERYMKSKTVASIMRHVASKLEQLYEEIAWPLGR--KYGHPYDAFKLALTEPDVVFSSLIARRLTPQPIKLRADIELTCYGIDAIKKALRAGEAQSNEIKAKLVAPPLYVLSTDKYAAVDRLERAIESIVKMKPKAVSETEEDLAQLMAKAGAENAEVSG Malgl1 RFYEKPLPDTDEIVMCQVRQIA--EMGAYVNLLEYDNAEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDVIKCEERYSKSRAVNSIVTHVAHKLEQLYEKVVWPLDR--TYGHSYDAFKLSVTESGKVFEGIIARRLTPQPVKIRADVEVSCFGIDAVKQALRAGEAVSTEIKIKLVAPPLYVLVTDKAGGIALMEHALEKIIKMKPKAVSAVEDELAQLMARVERENTEVQG Mellp23 RYYRPKFPEPDELVMVQVKQIQ--DMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVMRVDKEKG--YIDLSKRRVSAEDVVKCEERYNKSKTVSSIVRHVAEKVEAVNEMVAWPLFE--KYGHAFDAFKLSITEPETVFGELIARRLTPQPVKVRADLEATCFGIDAIRNALKLGESMGTEIKIRLVAPPLYVMVSDKQGAIELLESAIVSIVKMKPKAVSETDDELAALMERVARENKEVSG Mnele RYYEQKYPEVDEVVMVNVVQIA--EMGAYVKLLEYDGQKGMILMSEFSRKRIRSIN--KLVRVGRNECVLVTRVDQDKG--YIDLSKRRVVQEDIKRCEEKYSKAKTVNQILRHVGELLEELYKKTAWYFDK--KYGGSHEMFKEAAQKPE-ILDELIKRRLTPQAVKVRADVEVLCYGIDAVKAALRAGLALATELKINLIAPPIYVISVNEEKGVEAVRAAMDAIVKLEPKVVTEREDKLQEEMEQRERDMQEKDG Monbr RFYKPKFPEVDDVVMVNVKSIQ--EMGAYVQLLEYDGIDGMILLSELSRRRIRSLN--KLIRVGRHECVVVMRVDEEKG--YIDLSKRRVSPEEAKKCEDKFNRAKIVNSILRNVADNLETLYEQTAWKLEATSGPSSSFDLFKLAITEKPEIFDSFIQHRLTPQAEKIRADIDVTCYGINAVKAALKAAIALSTPINVNLIAPPLYVVTTDKTKGVALLGEALEAIIKMAPRAVTETDDELAKLMEKFEKENEEGSG Morel2 RMYANKFPEVDDLVMVNVRQIA--EMGAYVQLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGKNEVVVVLRVDKEKG--YIDLSKRRVSATDIVKCEERYNKSKAVHSIMSTVAKKLEVLYEQLAWPLYA--KYGHAYDAFKAALNEPEKVFEGLIKRRLTPQPIKIRADIEVTCFGIDAIKTAFKEAEAVSLPIRVKLVAPPLYVMITDKQLGIETMEKAIAVLTKMSPKAVTEADDELDQLLARIDKENAEVSG Mucci2 RMYENEFPKVDDVVMVNVRQIA--DMGAYVKLLEYGDREGMILLSELSRRRIRSVQ--KLIRVGRDEVVVVLRVDEEKG--YIDLSKRRVTPEDIIKCEEKYNKSKAVHSILRHVAEKLQDLYESIGWPLYK--KFGHAYDAFKMAIVDSEAVFAGIIKRRMTPHPVKIRAQLDLRCTGVNAIKAALKAGESVGSEIKITYLAAPFYVVTVDKKLGFDIIEKSIEAIVEKEAKLVSDSDDDFAALLAQAEKENELVSG Mydma --------------MVNVRSIA--DMGAYVHLLEYKNIEGMILLSELSRRRIRSIN--KLIRVGRNECVVVIRVDKEKG--YIDLSKRRVSIEEVKKCEEKYTRGKTVASILRHVGELLENLFEKTAWFFDD--KYGGAYEAFKHAVNEPS-ILNECINRRMMPQAVKVRADVEVSCYGIDAVKSALRKGLLFSTDIKINLIAPPLYVISTERELALEVLGKSIAAIVKMEPKVVTDTDEELSKELARLEQMNAEVDG Neucr2 RFYEEKYPEIDSFVMVNVKQIA--DMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVRCEERYNKSKIVHSIMRHVAEKIEQLYETIGWPLNK--KYGHSLDAFKLSITNPD-VWNDIISKRLTPQPTKVRADVEVTCFGIDAIKTALRTAEARNTEVKCRLVSPPLYVLTNDKNAGIARLQEAIQDMVKMEPKAVTESDDELQALMEKRERENAEVSG Orpsp11 RMYENKFPEVDDLVMVNVVQIA--DMGAYVHLLEYNNTEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDTEKG--YIDLSKRRVSAEDIQKCEEKFTKSKTVHSIMRHVAEKLEDLYVQIGWPLYK--KYGHAYDAFKAAIYEPDKVFEGLIKRRMTPQPIKLRGDIELTCFGIDAIKESLKIGEACSVKIKIKLVAPPLYVMTADKALGIETLEKAIAAIVKMSPRAVSENDEELQQLLARAERENAEVSA Pench1 RFYEDKYPEVDSFVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRIGRNEVVIVLRVDKEKG--YIDLSKRRVSPEDVIKCEERYNKSKAVHSIMRHVAEALETLYENIGWPLNQ--KYGHAHDAFKISITNPS-VWDEIINSKLTPHPTKVRADIEVTCFGIDAVKDALRAAEADNTPIKVRLVAPPLYVLASDKTLGVKLLEEAIVKIVKMAPKAVTEHDDILQELMEKRERENTQVSG Phybl2 RMYENEFPKVDDVVMANVRQIA--DMGAYVKLLEYGDREGMILLSELSRRRIRSVQ--KLIKVGRNEVVVVLRVDEEKG--YIDLSKRRVSPEDIAKCEEKFTKSKAVHSILRHVAEKLKDLYEMIGWPLYK--KFGHAFDAFKLAIADPEPVFEGLIKRRMTPQPVKIRAQLDLRCTGVNAIKAALIAGEAQSTEIKVTYLAAPFYVVTADKTAGFEVMELAVNAIVEKEAKLVSETDDDFAELMAQAEKENELVSG Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYMKSKTVASIMRHVASKLEALYEQVAWPLGK--TYGHPYDAFKLALTESEGVLSQLIARRLTPQPIKLRADIEVTCYGIDAIKKALRAGEKESTEIKAKLVAPPLYVLSTDKYAATERLERAIDSIVKMKPKAVSETDEDLAQLMAKAGQENAEVEG Polpo RMYEKKYPEENELVMVTVTSVG--EMGVYVSLLEYNNIEGMILLSEISRRRIRSLT--KLVRVGRQEVVVVVRVDKEKG--YIDLSKRRVTPEEITKCEERYNKSKAVHSIIRHLATRPKQLYKQFGWALYT--KYQHAYDAFRLSISEPA-VFEGFISHKLKPQPMKIRADLEMTCFGIDAIKAAVLASQNHAIQVTVTLIAPPLYVMVGDKEKGLAMLSKCVEILVKIPARAVGASDDELDDLMEQLERENELVDG Pucgr2 RYYRPRFPEPDELVMVQVKQIQ--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVMRVDKEKG--YIDLSKRRVSAEDVVKCEERYNKSKTVSSIVRHVSEKMETINEMVAWPLFE--KYGHAFDAFKLSITEPDTVFGDLIARRLTPQPVKVRADIEATCFGIDAIRTALKLGESIGTEIKIRLVAPPLYVMVSDKQGAIELLETAIERIVKMKPKAVSETDDELAALMERVARENKEVSG Punst1 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLHFN--PG--YIDLSKRRVSPEDIIKCEERYMKSKTVASILRHVATKLEQLYDKIAWPLGK--TYGHPYDAFKLALTEQDTVFSSLIARRLTPQPIKLRADIELTCYGIDAIKKALKAGEKVSSQIKAKLVAPPLYVLSTDKFSAVDRLERAIESIVKMKPKAVSETEDDLAQLMQKAALENQEVSG Rhior3 RMYENEFPKVDDVVMVNVRQIA--DMGAYVKLLEYGDREGMILLSELSRRRIRSVQ--KLIRVGRDEVVVVLRVDEEKG--YIDLSKRRVTPEDIIKCEEKYKKSKQVHSILRHVAEKLKTLYETIGWPLYK--KYGHAYDAFKMAILDTDAIFSGIIKRRMTPQPVKIRAQLDIRCTGVNAIKNALKAGEQVGDEVKITYLAAPFYVVTVDKEQGFQIIEKAIEAIVEKEAKVVSDSDDDFAALLAQAEKENELVSG Rhoto1 RYYENRFPEVDEVVMVQVKQIQ--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVMRVDKEKG--YIDLSKRRVSPEDVIKCEERYNKSKTVHTIVRHVAEKMDEIMELVAWPLYK--KYGHAFEAFKLSISEPETVFADMIARRLTPQPVKVRADIEVTNFGILTIQEALAAGESLSTEIKIRLVAPPLYVMVTDKQGAIERLEQAIEKIVKMKPKAVSETDDELAALMDRVARENKEVSG Rozal11 --------------MVNVRQIA--DMGAYVQLLEYNNIEGMILHSELSRRRIRSIQ--KLIRVGKNEAVVVLRVDKEKG--YIDLSKRRVSPEDIKKCEERYGKSKVVNSIVRMISEKMEDLNAKFIWPLYK--QFGHAYDAFKAALNDAEGVFKNVIQRRLAPQKVKFRADFEVQCAGINAVKEALIAGEKCGTELKIRLVAPPLYIMTTERQSTVELMEHSLKVIVKTKPRAMDDSDDEIAAMMEQAERENAQVSG Sacce1 RFYENKYPEIDDIVMVNVQQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGKNDVAVVLRVDKEKG--YIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKLEELYKTIAWPLSR--KFGHAYEAFKLSIIDET-VWEGIISKRLTPQAVKIRADVEVSCFGIDAIKDALKSAEDMSTEVKVKLVAAPLYVLTTDKQKGIEQLESAIEKIITMPPKAVTATEDELQALLESKELDNRSDSE Salro RFYKNKFPELEDVVMVEVKSIA--EMGAYVELLEYDGVEGMILLSELSRRRIRSIN--KLVRVGKTEAVVVLRVDEGRG--YIDLSKRRVSPDEVAKCENRYSEAKIVNSILRTVADALEELYEKTAWKLEEGDKPGSSYQAFKKAIVETPELFDTFVKHRLMPNTVKIRAEVDAQCYGIEAVKSALKAGLEESTDIQINLIAPPTYKIETDRKLGIDALNTCIERIVRSEPQAVSDEDEKLKERMDEAGQEEEEEEE Schco3 RYYEQKYPEVDELVMVQVRQIA--EMGAYVKLLEYDNTEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDITKCEERFMKSKSVASILRHVASKLEMLYETIAWPLGR--KFGHPYDAFKLALTEQDSVFSQLIARRLTPQPIKIRADIELTCYGIDAIKKALRAGEKESTDIKARLVAPPLYVLSTDKYAAVDRLERALESIVKMKPKAISEAEEDLEARMENAERENAEVSG Schpo1 RMYENRFPEVDELVVVNVRQIQ--EMGAYVKLLEYDNIEGMVLLSELSRRRIRSVQ--KHIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDVVKCEERFNKSKAVHSIMRHIAEKLETMYTTIGWPLYR--KYGHAYDAFKLAISNPDHVFEGLISRRLTPQPIKIRADVEVTCFGINAIKAALKAAEDVHTEIKVKLVAPPLYVLLTDKSLGLKKLEEAIGAIVKMKPKAVSETDEELADLMKKFEKENAEISG Sorma RFYEEKYPEIDSFVMVNVKQIA--DMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVRCEERYNKSKIVHSIMRHVAEKIEQLYETIGWPLNK--KYGHSLDAFKLSITNPD-VWNEIISKRLTPQPTKVRADVEVTCFGIDAIKTALRTAEARNTEVKCRLVSPPLYVLTNDKNAGIARLQEAIQDMVKMEPKAVTESDDELQALMEKRERENAEVSG Sphar RFYEKRFPDKDEVVMVNVRSIA--EMGAYVSLLEYDGIEGMILLSELSRRRIRSIA--RLIRVGRNEAVMVLRVDEDKG--YIDLSKRRVSPEDVKACDDKYQKNKAVNSILRHVAELLEDLYERTAWKLVA--AYGTQYEAFRKALTEPEEVMGKLISRRLASQPSKIRADIDVHCWGVEAVKDALRAGIAVGTEVKVNLIAPPLYAVTTDKDEGIKAVNKAVDAIVIKEARAINELEEKLQEEIENEDEVEEEETG Spipu1 RMYEQKFPEVDQLVMVNVRQIA--EMGAYVHLLEYNNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSAEDVAKCEEKFNKSKAVHSIMRHVAEKLEELYEKFGWPLYR--KYGHAYEAFKLAIAEPETVFEGLIRRRLTPQPVKIRADIEVTCFGIDAIKTALQAGEACSTEIKVKLVAPPMYVVMTEKSGGIEIMEKAIATIVKMKPRVVSATDDELAQLMARVERENAEVSG Sporo1 RYYADRFPEVDELVMVQVKQIQ--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVMRVDKEKG--YIDLSKRRVSAEDVIKCEEKYNKSKTVHTIMRHVAEKMEQINDLVAWPLYK--KYGHAYDAFKLSITEPESVFSDLIARRLTPQPVKIRADLEVTNFGILTIQDALAAGEALSTEIKIRLVAPPLYVMVSDKTGAIERLEQAIEAIVKMRPKAVSETDDELAALMDRVARENKEVSG Stehi1 RYYEQRYPEVDELVMVQVRQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDITKCEERYMKSKTVASILRHVATKLEKLYEQIAWPLNK--KYAHPYDAFKVALTEADTVFSNLIARRLTPQPIKLRADIELTCYGIDAIKKALREGERSSTEIKAKLVAPPLYVLSTDKFGAVERLERAIESIIKMRPKAVSDTEEDLAQLMAKASAENAEVSG Tapde11 RYYENKLPEVDELTVVNVRQIA--EMGAYVRLLEYDNTEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIAKCEERYNKSKAVHSIMRNVADKLESLYESVGWPLYR--KYGHAYDAFKLAITQPDSVFADIIARRLTPQAIKIRADVEVTCFGIDAIKTALRAADKVNTEVQVKLVAAPLFVVLTDKVVGIKLLEDAIAEIVKTSPRAQSEQDDELQKMMEKAEAENLEVSG Thetr RMYEKKFPDIDEPVMVNVRSVA--EMGAYVALLEYNNIEGMILLSELSKRRIRSIP--KLIRVGRNEVVAVLRVDKEKG--YIDLSKRRVEEKDIAQLEEKYAKSKEVHTIMRQTAKVLEDLYVQFGWPLYK--KYGHAYIGFCKAIQNEEEVFGEFIRRRLTPSAVRLRADVEVSCDGIEAIKRALRAGEISAADVSVKLVAPPLYVFLTNTDKGTALLNEAIARTLKIPPRATSERDEDFTALLKDLERANAEVDG Treme1 RFYEKKYPDVDELVMVQVMSIE--DMGAYVKLLEYDNIEGMILLSELSRRRIRSVQ--KLIRVGRNEVVVVMRVDPDKG--YIDLSKRRVSAEEVVRCSEQYEKGKTVDSILTQVARKAESLYEKIAWPLHK--QYGHTYDAFKLSISEPDHVFAPLIARRLTPKPVKVRADIEVKCFGIDAIRRALQAGEAVSTEIKVRLVAPPLYVMTTDKVAAIDLMEQAVERIVKMKPKVVSETEDELKALMDKFEAQNMDVAG Trire2 RFYEEKYPEIDSFVMVNVKQIA--EMGAYVKLLEYDNIDGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDIVKCEERYNKSKMVHSIMRHVAEKIESLYESITWPLNR--KYGHAIDAFKLSITNPE-VWDDIISKRLTPQPTKVRADVEVTCFGIDAVKAALRTAEAKNTEVKVRLVSPPLYVLTSDKAQGITRLEEAIVDIVKMEPKAVTESDDELQALMEKRERENAEVSG Umbra1 RMYEKEFPEVDDLVMVNVRQIA--DMGAYVKLLEYNDREGMILLSELSRRRIRSVQ--KLIRVNRNEVVVVLRVDEEKG--YIDLSKRRVSPEEISKCEEKYNKSKAVHSILRHVAEKLKELYETIGWPLYK--KYGHAFDAFKMAIIQPEEVFEGIIKRRMTPQPVKIRAQLDLRCTGVNAIKAALTAGEAVSTEIKVTYLAAPLYVVTADKQLGFEVMEKAIQVMVEKDAQLVSENDDDFAALMAKAEKENELVSG Ustma22 RFYKKELPDVDEVVMCQVQQIA--EMGAYVKLLEYDGAEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDVIKCEEQFTKSKAVHSIIAHVAGKVEELYDTIVFPLHE--KYGHAFDAFKLAILDMDKTFEGIIARRMTPQPVKIRADVEVTCFGIDAVKKALRAGEAVSTEIKIKLVAPPLYVLITDKVGGIALMEQALEKIIKMKPKTVSEVEDELEQLMAHFEKQNAEVEG Walse1 RFYSQKFPEVDELVMVQVRQIA--EMGAYVKLLEYDGIEGMILLSELSRRRIRSIQ--KLIRVGRNEVVVVLRVDKEKG--YIDLSKRRVSPEDVLKCEERFNKSKAVHSIMSHVSGKMEKLYEDVAWPLHN--KYGHSYDAFKLSISEPEMIFSQLISRRLTPQPVKIRSDLEVTCFGIDAIKGALKAGEALQTEIKIKLVAPPLYVISTDKAGGLALLEKAVALVIKMKPKAVSESEDELQALMERVERENKEVSG Zygro1 RFYENKYPEVDDIVMVNVQQIA--EMGAYVKLLEYDNIEGMILLSELSRRRIRSIQ--KLIRVGKNDVVVVLRVDKEKG--YIDLSKRRVSSEDIIKCEERYQKSKTVHAILRYCAEKLEDLYKTIAWPLSR--KYGHAYEAFKLSIIDQS-VWEGIISKRLTPQAVKIRADVEVSCFGIDAIKNALMEAESLSTEIKVKLVAAPLYVITTDKQQGIEVLQNAIEKIITMPPKAVTATEDELQALLESKELDNRSDSD [Cluster1917.fasta_al_trimmed; alignment length = 130] Allma1 GSGGVAGQSESNVDRRERLRKLAL--ETILAKDPYILKNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQANLARRAAREK-IG-RPGYTVTKVRDGFLFRIEYPHRFMGAYEFQYVVVAAEPYETVAFKI Ashgo11 GGGGIASQSQQNVHRRKQVEDLLRGGEDVLKRNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNLLRRGGSTH-NGVVPKVQFTKVKDGIAVRVDYKLRILSGLEKKYLVVAYEPFENIAIEI Aspfu1 GGGGVASHSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAREK-IG-RPGYKITKIRDGLLFQLQYQVRFMSAFEFQYLVVAAEPYQTCGFKL Aurde31 GGGGVAGASESNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMLVQVHLPKRFMSCWEYQYLIVAAEPYESVAFRI Batde5 GSGGVADSSQFNVDRRERLRKLAS--ETILTKDPYFMKNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQTNLARRAAKDK-IG-RPGYKVTKVRDGLLFQVHYPHRFMSAYEFQYLLIAAEPYETIAFKV Botbo1 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVREGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Botci1 GGGGVASTSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAREK-IG-RPGYKITKTRDGLLFQLQYPVRFMSAFEFQYMLVAAEPYETCGFKL Caeel GSGGVASAADAGVDRRERLRQLAL--ETILQKDPYFMRNHIGTYECKLCLTLHNNEGSYLAHTQGKKHQANLARRAAKEK-IG-RPGYKVTKERDALLFQIDYPHRFMSAYEWQYLLFAAEPYETIGFKI Canalb1 GAGGIASNEDINIQTKQRVQELLS--THVIDNDPYVFRNHLGMLECKLCLTTHINESSYISHLGGRKHHLNLERRRILDK-IG-KPIYKITKVRDGILVNIKLPFRIMSYYEYQYLVVSAEPYDNIAIVI Cangl GGGGIASDSQINQQRRRQVEELLQQGENIVQSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGMNVIRRGELDTIEGLVPTCHSTEVIDGIAVMLEFEARIVSGLEKRFLVVAYEPYQNVAIEI Capow GGGGMASAAESNLARKRRLRELAS--EVIVTKDPYLLRSHLGTYECKLCLTLHSNEGSYLAHSQGKKHQEQLAKRAARDK-IG-RPGYNVTKQRDSLFFQVDLPHRFMSAFEWQYLLVAAEPYETIAFRL Catan2 GSGGVAGSSESNVDRRERLRKLAM--ESIIAKDPYILKNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQANLARRAAREK-IG-RPGYQVIKVRDGFLFTIELPHRFMGAYEWQYLVVAAEPYETIAFKI Cioin GSGGVASLSDANRDRRERLRQLAL--ETILNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQSNLAKRAARDK-IG-RPGYKVTKQRVSLLFQVDYPHRFMSAYEWQYLLFAAEPYETVAFKV CocheC53 GGGGVASQSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAKEK-IG-RPGYHITKVRDGLLFQFQFPVRIMSAYEYQYLIVAGEPYETVAVKL Coere1 GAGALMTHSESNVARRERLRKLAL--ETIIESDPYFMRNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYKVTKIRDGLLFEITYPHRFMSAYEYQYLLFAAEPYETIAFKI Conco1 ---------------------------------------------------------------------------------------------------------------------------------- Conpu1 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEFQYLIVAAEPYETIAFRI Copci GGGGVAGASESNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKIRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Croqu1 GGGGVAGASEANVDRRERLRKLAL--ETILAKDPYILRNHLGGLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAAKDK-IG-SPGYQVTKVRDGLLFQIHYPHRFMSSFEHQYLLIAAEPYQTIAFKL CryneH991 GSGGVAGASETAVDRRERLRKLAL--ETILAKDPYILRTHLGTLECRLCLTLHVNEGSYLAHTQGKKHQTNLARRAAKDK-IG-RPGYKIIKIREGLLFTVSLPRRFMSAFEFQYLVLAAEPYETIAFAI Crypa2 GGGGVASHSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGKKHQTNLARRAAKEK-IG-RPGYKITKVRDGLLFQLQYPWQIMSAFSFQYLCVAAEPYETCGFKI Debha1 GSGGVADVQETKVHTRRRLKELLT--TQVLDSDPYVFRNHLGLLECRLCLTTHVSESSYISHIGGRKHQMNLEKRQILDK-SG-RPAFKVTKIRNGLLINAKYPFRIMSYYEWQYLVITAEPYENICFAI Dekbr2 GSGGIAGDAETNQYRKERLRKLLL--SKVIEADPYVIRNHMGVLECKLCFTTHFSEGSYLTHTHGRKHQFNLMKRVEAEK-IG-KPAYRISKVRDGLTFHLKYPYRLMSSFEFQYVIISGEPYENIGFKI Dicdi GSGGLQSSQYDNIDRRERQKQLVL--EHVVSKDPYIISNHIGSFECRLCLTVHNNVGNYLAHTQGKKHQTHLARRAAKEK-IG-RPGYKIIKQRDSLLFQIDYPHRIMSAFEYQYLLFAAEPYETIAFKI Dmel GSGGVASWSETNRDRKERLRQLAL--ETILNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQDNLARRAAKEK-IG-RPGYRVTKQRESLLFQVDYPHRFMSAYEWQYLLFAAEPYETIGFKV Enthi GSGGLATLAETAAARKERLKQLAL--ERILSKDPYFYKTHVGTYQCKLCLTTHLTEANYLAHTQGKRHQQNLRARELKEK-IG-TPGFSITKQIDSLAITVNLPFKIMGAFEYQYLIIAAEPYQSIAFKI Falba GGGGMASESESNLQRRLRLQKLAS--EFVLKKDPYFMKNHLGSYECRLCLTLHTSEGSYLAHTQGKKHQTNLARRKARDR-IG-RPGFQVTKVRDGLLFEIDYPHRFMSTYEYQFLVFAAEPYTNIAFKL Fomme1 GGGGVAGASEANVDRRERLRKLAM--ETILAKDPYILRNHLGSYECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Fusgr1 GGGGVASQSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGKKHQTNLARRAAREK-IG-RPGYKITKIRDGLLFQLQYPWQVMNAFTFQYLLVAAEPYETVGFKI Galma1 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRV Ganpr1 GSGGVAGYSESNVDRRERLRKLAL--ETILAKDPYFMKNHLGTYECKLCLTLHTNEGSYLAHTQGKKHQTNLARRAAKDK-IG-RPGYNVTKVRDGLLFQVFYPHRFMNAFEIQYLIFAAEPYENVSFRV Gloin1 GSGGVAGYSETNVDRRERLRKLAL--ETILNKDPYFMKNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQTNLARRAAREK-IG-RPGYKVTKVRDGLFFQIQYPHRFMSAYEHQYLLFAAEPYETIAFKV Hisca1 GGGGVASHSATNADRRERLRKLAL--ENILEKDPYFFKNHIGSFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAREK-IG-RPGYKITKTRDGLLFQLQYQVRFMSAFEFQYLLVCGRTARSFGYRL Klula1 GSGGIASDSQQNLQRRKQVQDLLSNGQDILRANPDIYKNHSGRLVCKLCNTLHVSWSSVERHLTGKKHQLNVLKRGGRNK-NGIKPEVKVVKVRHGIAVKVRYGLRIVSDFEVKYLVVAFEPFENVGIQI Lacbi2 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Lenti61 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Malgl1 -GAGIANASDAAIDRRERLRRLAM--ETIISKDPYILRNHLGGLECRLCLTMHANEGSYLAHTQGKKHQTNLQRRAALGK-IG-RPGYRITKIREGLVFEVSLPHRFMSSFEWQYLLVAAEPYETIAFKL Mellp23 GGGGVAGASEANVDRRERLRKLAL--ETILAKDPYILRNHLGGLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAAKDK-IG-SPGYQVTKVRDGLLFQIHYPHRFMSSFEHQYLLIAAEPYQTIAFKL Mnele GGGGVASFSESNRDRRERLRQLAL--ETILNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQQNLARRAAKEK-IG-RPGYKVTKQKDSLLFQIDYPHRFMSAYEWQYLLFAAEPYETIAFKI Monbr TGSGYASWDDANRMRKERLMALAM--ETILAKDPYFMRNHIGKYECKLCLTLHNNEGSYLAHTQGKKHQENLRKRAAKD--------------------EVDYPHRFMSAYEYQFLLFAAEPYETIAFKA Morel2 GGAGVAGASESNVDRRERLRKLAL--ETILAKDPYFMRNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQTNLGRRAAKDK-IG-LPGYKVTKIRDGLLFEIAYPYRFMSAYEHQYLVIAAEPYETISFKV Mucci2 RGGGMASASESNVDRRERLRKLAM--ETIISKDPYFMKNHLGSYECKLCLTLHTSEGSYLAHTQGKKHQTNLARRAAKEK-IG-RPGYRVTKVRDGLLFQIQYPHRFMGAYEYQYVVIAAEPYESIAFKI Mydma GSGGVASWSETNKDRRERLRQLAL--ETILNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQQNLARRAAKDK-IG-RPGYKVTKQSDSLLFQIDYPHRFMSAYEWQYLLVAAEPYETIGFKI Neucr2 GGGGVASHSATNADRRERLRKLAL--ETILDKDPYIFRNHLGSFECRLCLTVHQNDGSYLAHTQGKKHQTNLARRAAREK-IG-RPGYKITKVRDGLLFQLQYPWQVMSAFSYQYLLVAAEPYETCGFKI Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------- Pench1 GGGGVASKSATNADRRERLRKLAM--ETIIEKDPYIFKNHLGTFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAREK-IG-RPGYKITKILDGLLFQLQFQVRFMSAFEYQYLVVAAEPYQTCAFKL Phybl2 RSGGVASWSESNVDRRERLRKLAL--ETIISKDPYFMKNHLGSYECKLCLTLHTSEGSYLAHTQGKKHQTNLARRASKEK-IG-RPGYRVTKVRDGLLFQVQYPHRFMAAYEYQYLLIAAEPYETIAFKV Picst3 GAGGVAGAEETNVHTRQRIKELLA--TQVLDNDPYVFRNHLGLLECRLCLTTHVSELSYISHLGGKKHRMGLEKRRALDK-VG-KPAYKLTKIRDGLLVDIKYPFRFMSYYELQYLVISAEPYENICFII Plicr1 GGGGVAGASETNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Polpo GGGGLQSSQYDNIDRRERLKQIAL--ETIISKDPYIISNHLGSYDCKLCLTVHNNIGNYLAHTQGKKHQTNLARRAARDK-IG-RPGYKIIKQRDSLLFQIDYPHRFMSSFEFQYLLFAAEPYETIAFKI Pucgr2 GGGGLAGASEANVDRRERLRKLAL--ETILAKDPYILRNHLGGLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAAKDK-IG-SPGYQVTKVRDGLLFQIHYPHRFMSSFEHQYLLIAAEPYQTIAFKL Punst1 GGGGVAGASESNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Rhior3 RGGGVASYSESNVDRRERLRKLAM--ETIISKDPYFMKNHLGSYECKLCLTLHTSEGSYLAHTQGKKHQTNLARRAAKEK-IG-RPGYRITKVRDGFLFQIQYPHRFMGAYEYQYVVIAAEPYESIAFKI Rhoto1 GGGGVARADETAIDRRERLRKLAL--ETILAKDPYILRNHLGGIECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-SPGYQVTKVRDGLLFQVHYPHRFMSAFEWQYLLIAAEPYQTISFKI Rozal11 GSGPLASWSEENAARKERFKKIAF--ESVLANDPYLMKNHLGSYECKLCLTIHMNEGSYLVHTQGKKHQTNLARRQAREK-IG-RPGYKVTKIRDGLLFQIKYPYRFMSSFEFQYVLFAAEPYETIAFKV Sacce1 GGGGIASESQFNLQRRKEVESLLSKGENVVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIN-NGTIPVCKIATVKNGLAIQVNYSIRIVSGLEKKFLVIAYEPFENIAIEL Salro GGGGPASFSESNRQRKERLMALAM--ETILAKDPYFMKNHLGKYECKLCLTLHNNEGSYLAHTQGKRHQENLRIRAIKEK-VG-RPGYKVTKQRDSLFFQIDYPHRFMSAYEFQFIVFAAEPYETIAFKI Schco3 GGGGVAGASESNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGLMVQVHLPRRFMSAFEHQYLIVAAEPYETIAFRI Schpo1 GGGGVAGYQETNAARRERLRKLAL--ETILSKDPYLMKNHLGTFECRLCLTTHANENSYLTHTQGKKHQTNLARRQALEK-IG-RPGYKVSKIREGLRFQIKYPYRIMSAYEFQYLVVAAEPYESIAFKI Sorma GGGGVASHSATNADRRERLRKLAL--ETILDKDPPSKRRLLPR------------------PTQGKKHQTNLARRAAREK-IG-RPGYKITKVRDGLLFQLQYPWQVMSAFSYQYLLVAAEPYETCGFKI Sphar ------------------------------------MRNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQYNLAGRAAKEK-IG-RPGYKVTKQKDSLLFQIDYPHRLMSAYEWQYVLVAAEPYETIAFKI Spipu1 GSAGVAGGSESNVDRRERLRKLAL--ETILAKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQTNLARRAAKDK-IG-RPGYKVTKIRDGLLFQIQYPHRFMSAYEFQYLLFAAEPYETISFKV Sporo1 GGGGVAGQAEQAVDRRERLRKLAL--ETILAKDPYILRNHLGGLECRLCLTIHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-MPGYQVTKVRDGLLFQVHYPHRFMSSFEWQYLLIAAEPYQTISFKI Stehi1 GGGGVAGASESNVDRRERLRKLAL--ETILAKDPYILRNHLGSLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYRVTKVRDGMMVQVHLPRRFMSAWEYQYLIVAAEPYETIAFRI Tapde11 GGGGVAGRSETNADRRERLKKLAL--ETILNKDPYFFRNHLGTYECKLCLTAHANDGSYLAHTQGKKHQTNLARRAARDR-IG-RPGYKIQKIRDGLFFQLFFPYRFMSAYEWQYLVISADPYDAVAFKI Thetr GSGAVASASVANRARRERIRALAL--TTILKSDPFFTRTHHGHYECSLCLTHHSNEGSYLAHTQARKHRQNLAKRQARQT-IG-VPHHAVERLLDGLRISIAYPHQFMSAYEYLYLVFAADPYSNVAVKI Treme1 GGGGVAGDSETAVDRRERLRKLAL--ETILAKDPYILRTHLGTLECRLCLTLHINEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYKIIKIRDGLLFTVSLPRRFMSAFEFQYFVLAAEPYETIAFAI Trire2 GGGGVASHSATNADRRERLRKLAL--ETILDKDPYFFKNHVGSFECRLCLTVHQNDGSYLAHTQGKKHQTNLARRAAREK-IG-RPGYKITKIRDGLLFQLQYPWQVMNAFTFQYLVVAAEPYESVGFKI Umbra1 GGGGVASASESNVNRRERLRKLAL--ETIISKDPYFMKNHLGSYECKLCLTLHTNEGSYLAHTQGKKHQTNLARRAARDK-IG-RPGYKVTKVRDGLLFQVQLPHRFMSAYEHQYLLIAAEPYETISFKV Ustma22 -GGGIAGASESNVDRRDRLRKLAL--ETILAKDPYLLKNHLGGLECRLCLTLHTNEGSYLAHTQGKKHQTNLARRAAREK-IG-RPGYKVSKVREGLLFQISLPHRFMGSFEYQYLVVAAEPYETIAFKL Walse1 GGGGMYGEAESNADRRERLRKLAL--ETILAKDPYILRTHLGTIECKLCLTLHPNEGSYLAHTQGKKHQTNLARRAAKEK-IG-RPGYKVTKVKQGLMFQVHYPRRLMSAFEYQYLLIAAEPYETIAFRI Zygro1 GGGGIASDSQANLARRKQVDELLRQGQQVLNRNPYIYKNHSGKLVCKLCNTIHTAWSSVERHLSGNKHGLNVLRRGSANH-NGIVPDCKTALVKDGIAIQVDYNIRIVSGLEKKYVVIAYEPFENVAIEI [Cluster1926.fasta_al_trimmed; alignment length = 118] Allma1 AKDLAAFRKQYEAEPSADTTFNLAWGLVHSPSASDGERLLLEL-HKTAPHL--RRDVRYYLGLAAFKQAKFADARTYLLRDEPQNTQALALLDAVNQQVDGLIGMAI-VGGAVAAVGL Ashgo11 AEQLDILRQQVLSEASIQSRFNYAWGLVKSHDAEDGVKLLTDI-YKESPMR--RRESLYYLAIGCYKLGEYAMAKRYLVAHEPDNAQARTLKAMVEQKIEGLKGAAL-VGAGLAAVAA Aspfu1 PAELQVLRAQYEKEVGIQTKFNYAWGLIKSNARTDGVRLLSEI-FRAAPER--RRECLYYLALGNYKLGNYGEARRYLLEKEPGNLQAASLGSLIDDKVEGLMGIAI-VGGLAIVGGL Aurde31 YDELEVLRLQYEKEVTVQTRFNYAWGLVKSPQHRDGVKLLSDI-FRSEPTR--RRECLYYLALGHYKMKNYREARDFLLEKEPNNLQAQSLAQLIEKADESYIGMAL-LGGVAAVGAV Batde5 QEELQTIRDLYKKEVSPQVKFNYAWALVRSTKRQDGVDLLHAI-YRENPGR--RRECLYYLALGEYKLGNYTKARRYLLNMEPSNPQALALKTLIAEHVEGLVGMAI-VGGMVAVVGI Botbo1 FDELEVLRLQYNKEITTQTKFNYAWGLVKSPLREHGVRLLQDL-YRADSTR--RRECLYYLALGHYKMGNYDEARKFLLEKEPSNMQAQSLASLIDRSTEGYVGMAI-AGGVAAVGAV Botci1 PAELQVLRAQYEKEVGVQTQFNYAWGLIKSNSRHEGVRLLSDI-FRTSPER--RRECLYYLALGNYKLGNYSEARRYLMEKEPENLQASSLKGLIDDKVEGLIGVAI-LSGVAVVGSM Caeel PAVLMNAREQYMRQPSAASTFAFAHAMIGSKNKLDGIVCLEKL-LRDDEDRTSKRNYVYYLAVAHARIKQYDLALGYLLDAEGDNQQAKTLKESIKSAMDGLIGAAI-VGGGALAG-- Canalb1 QEQFRILKDQLNSEPSAQTKFNYAWGLIKSNHHKQGVQILTEL-YKSEKSM--RREVLYYLSLGSLKIGDYTNAKRYLLEIEPENQQARGLLKTIDDKIEGLIGIGI-AGGALAVGLG Cangl AAQIDILREQVVAEASVQSRFNYAWGLIKSESVDDGVKILTDI-YKESYQR--RRECLYYLTVGCYKLKEYSMAKRYLHEAEPNNKQVIALKEMVEDKIETIKGLAM-VTGAIVGIAS Capow DVDVERFEREHNDLSTDNAKFNYAWCLVKSRFRGDGIEMFQDL-LASGDRD---RECLFFIALGYYRLGEYPNARVYLLQIEPRNRQALQLDAAIDKLVDTLIGAAV-VGGLSIVG-- Catan2 QKDLAMLRKQYEAEPSSSTTFNYAWGLVHSNRREEGVELLTQL-VRTAPTM--RDEARYYAALGCFKMGEFSRARDMILKDHPNNPQALSIVDAVDEQVDGMIGMAI-VGGAVAAVGL Cioin PQEIMKFEKKYKKEVSSTTAFEYAWCLIRSRYSDDGFSLLKKL-YEKERDGQAKRDYLYYMAVAKYRLKEYEEALKFILKVEPKNHQVKELKEIINRKMEGLLGMAM-IGGAGVVG-- CocheC53 PEELQVLRAQYEKEVGLQTKFNYAWGLIKSTSRPDGVRLLSEI-FRNSRER--RRECLYYLALGNYKLGNYAEARRYLLELEPANLQAGSLKSLIDEKVEGLVGAAI-VGGIVVVGSL Coere1 ADELLVLQRQYEREARIQTKFNYAWGLIKSPNKREGVSLMHDI-YNEKAER--KRECLYYLGIGYYKMGEYGNARVHLLALEPNNAQARSLRELIDEKVDGMIGLAV-SGGAVALLGI Conco1 AEELEALKTAYETE-SAQAKIDYAWGLIKTKPKKEWARILAEL-KLSHPEH--LEAIHYYEALGHYQLGSYTQAKTLVLAKDDKNIQAKALQSMIDRSVEGACGILVTIAGIALIAGI Conpu1 ---------------------------------------------------------------------------------------------------------------------- Copci YDELEVLRLQYQKEVTTQTKFNYAWGLVKSPIRDHGVRLLQDI-YRTEPTR--RRECLYYLALGHYKMGNYEEAKKFLMEKEPANLQAQSLNQLIDNKIQGYIGMAI-VGGAATLGAI Croqu1 PSELTVLREQYKNEVSTQTKFNLAWGLVKGSTKNGGIAIFMDV-YREEPSR--RRECLYYLSLGHYKIGNYNEAKRFLLEKEPGNMQAQSLSQLIENGVEGYIGLSL-VGGAAVVGSL CryneH991 PDELEVLRRQYYREVTIQSKFNYGWGLIKSPSPELGVKLLQEI-YSASPDH--RRECTYYIAVGYYKLRNYAYARKFLLSVEPGNMQAQSLSTLIENAVDGLVGIGM-ITGAVAVVGL Crypa2 PAELQVLRAQYEKEVGVQTKFNYAWGLVKSTRRDDGVVFLSEI-FRTSPER--RRECLYYLALGNFKLGNYAEARRYLLEKEPANLQASDLRTLIDDKVEGLMGVAI-VSGLAVIGGV Debha1 SEQLRILKDQVESEPAPQSQFNYAWGLIKSSNYKMGISILSEL-YRDVPSM--RRECLYYLALGSYKIGDYSNATRYLLKNEPENKQAQDLKKSIHEKVEGLIGIGI-AGGALAVGVG Dekbr2 DPQLAILRKQVESEPTIQSLFNYAWGLVKSKDKGDGINILTGI-FKKEPSR--RRECLYYLSVGCYKIGEYKESERYLLDHEPDNLQAKELKDEIHNELNSVIGLAI-LSGLTAAGVG Dicdi ---------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------MILEEL-ARTHPDG--RRDYIYYLAFGNARIKEYTSGLKYFLDIE-SNDQVRSLEEYIKKEIEVAKGMVV-AGGAAVLGGI Enthi ---------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------- Fomme1 YDELEVLRLQYEKEVTVQSKFNYAWGLVKSPKYEDGVKLLQEI-YRAEPAR--RRECLYYLALGQYKMGNYEEAKRFLLDKEPHNMQAQSLAELIDQKMEGYIGLAL-AGGAAAIGTL Fusgr1 PSELNVLKAQYDREVGVQTKFNYAWGLVKSNQRNDGVRLLSDI-FRVSPER--RRECLYYLALGNYKLGNYGEARRYLLDKEPANLQASNLRSLIDDKVEGLMGVAI-LSGVGVVGAF Galma1 FDELEVLRLQYQKEVTIQTKFNYAWGLVKSPIHEHGVRLLQEI-FRAEPTR--RRECLYYLALGHYKMGNFEEARKFLLEKEPTNLQAQSLSQLIEKGADGYIGMAL-VGGAAALGTL Ganpr1 ---IQVIREQYQREPSVQTTFNYAWGLVRSGNKQDGMKVLWGL-YKNQPHL--SRECLFYLCIGHLKLGNYSDARKYLLKEEPSNTQFEALKDLIDQRVEGLTGMAI-VGGAAAVS-- Gloin1 IEELSVLRRQYEREATTQTKFNYAWGLIKGRKATDGVRLLTEI-YNDIPER--RRECLYYLALGNYKLGNYKDAKSYLIDKEPKNLQAQSLRDLIEQKVEGMMGMMI-TGGIVAVGAI Hisca1 PAELQVLRAQYEKEVGVQTKFNYAWGLIKSNTRQEGVRLLSEI-FKSARER--RRECLYYLALGNYKLGNYGEARRYLLDHEPGNLQAASLRTLIDEKVEGLVGVAI-LGGVAVVGGL Klula1 SDQIEILRQQVLNESSIQSRFNYAWGLVRSTNKEDGVKLLTDI-YKESPMR--RRECLYYLTIGCYKLGEYSTAKRYLVHHEPENKQALMLQTAVENKIQGLKGIAL-ISAGIAIGAT Lacbi2 YDELDVLRIQYQKEVTIQTKFNYAWGLVKSPVRDHGVRILQDI-YRGEPTR--RRECLYYLALGHYKMGNFDEAKRFLLEKEPSNLQAQSLAQLIDKGVEGYIGMAL-AGGVAAIGTI Lenti61 YDELEVLRLQYQKEVTVQTKFNYAWGLVKSPLREHGVRLLQDI-YRQEPGR--RRECLYYLALGHYKMGNYEEARRFLLDKEPTNLQAQSLATLIDKRVEGYIGMAI-VGGVAAFSTL Malgl1 ---------------------------------------------------------------------------------------------------------------------- Mellp23 TEELKVLRQQYQTEVSIQTKFNLAWGLVKGNVKNGGIAIFMDV-YRQEPTR--RRECLYYLSLGHYKLGNYGEAKRFLLEKEPSNLQAKSLSELITKGVEGYIGMSL-MGGAAIVGSI Mnele EQDIIEHERLYNEEVSSRTQFGYAYVLVKSPYDNDGIRLLEEL-CQSGVDQ---RDFVYYLAVGHYRLHDYTPAMKYVLEMEPGNQQATQLLEIIKKKRDAMIGAAV-LGGGALTGGL Monbr ---------------------------------------------------------------------------------------------------------------------- Morel2 DSQLEVLKKQYIREVTEQTRFNYAWGLIKSKNRREGVLLLTDI-YREVPDR--RRECLFYLALGHFKLGNYNDARKFLLEFEPNNHQAHALRQEIEDRVEGYIGMAI-VGTVAAVGTI Mucci2 PAELEVLRRQYIKEVTIQTKFNYAWGLVKSSKTEHGIKLLTEI-YTDAPER--RRECLYFLAIGNFKISNYSEARRFLLKLEPRNDQALALKQLIDEKVEGVIGLAI-VSGVVAVGAA Mydma EEDFSRFQNSYN-AVSPETQFQYGWCLIKSQYKDDGIKLLEAL-CATNMDS---RDFLYFIALGYYKLSEYDKALRFLLNIEPNNAQAKELEKSIESKMDGVMGIAM-VGGAAAVGGI Neucr2 PAELNVLRAQYEKEVGVQTKFNYAWGLVKSNVRADGVMLLSEI-FRTSPER--RRECLYYLALGNYKLGNYAQARKYLLENEPANLQAANLRALIDDKVEGLMGVAI-ISGVAVIGGV Orpsp11 ---------------------------------------------------------------------------------------------------------------------- Pench1 PAELQVLRAQYEKEVGIQTKFNYAWGLIKSNIRSEGVRLLSEI-FRGAPER--RRECLYYLALGNFKLGNYGEARRYLLEKEPANLQAASLGSLIDDKVEGLVGVAI-VGGLAVVGSL Phybl2 PAELQVLKKQFEREVTTQTKFNYAWGLVKSRQSDQALTLLTEI-YTECPNR--RRECLYYLALGHYKISNFNEARQFLLKLEPRNEQALELQRLIDEKLEGVIGLAI-ISSVVAVGAA Picst3 NQQLQILKNQVEAEVSPQTTFNYAWGLIKSSNHKHGVRLLTGV-FRDVPSM--RRECLYYLSLGSYKIGDYTNARRYLLDAEPENSQARALKVTIDDQVEGLIGLGI-VGGAIAIGLG Plicr1 YDELEVLRLQYQKEVTIQTKFNYAWGLVKSPRREHGVRILQEI-YRAEPNR--RRECLYYLALGHYKMGNFEEAKKFLIEKEPTNMQAQSLSSLIDSGVEGYIGMAL-AGGAAALGTI Polpo ---------------------------------------------------------------------------------------------------------------------- Pucgr2 PEELTVLREQYQNEISTQTKFNLAWGLVKGNARQGGIAILMDV-YRTDATR--RRECLYYLSLGHYKLGNYSEAKRFLLEKEPHNLQAKSLAQLIEKAVEGYLGLSL-AGGAALVGGV Punst1 YDELDVLRLQYEREVTVQTKFNYAWGLVKSPLREHGVRLLQEI-YRAEPGR--RRECLYYLALGHYKMGNYEEARKFLLDKEPQNMQAQSLESLIEKKVEGYIGMAL-AAGAAAVGTL Rhior3 PAELEVLRRQYIKEVTVQTKFNYAWGLIRSAKTDHGIKLLT--------------------AIGNFKISNYAEARRFLLKLEPRNEQAAGLKKLIDEKVKGVIGLAI-VSGVVAVGAA Rhoto1 ASELNVLRQQYLDEVSVQTKFNYAWGSVKSDNRVEGVALLMDI-YRTEPSR--RRECLYFLAVGHYKLGNYPEAKRYLLEKEPNNIQAQSLQQLIEQAVEGYVGMAI-AGGAAAAVGI Rozal11 LSQITEAKQVFQSQFTPYLEFAYCSTLIHSPLKQDSYSRLKILLETYVPES----DVYFQLAKVCIRLQEYKEAKKYLQKTHPE--QSNKLLSIVNDRVDGLMGMML-VAGVGVVSGL Sacce1 PQQLEILRQQVVSEATIQSRFNYAWGLIKSTDVNDGVKILTDI-YKEAESR--RRECLYYLTIGCYKLGEYSMAKRYLFEHERNNKQVGALKSMVEDKIETLKGVVV-AGGVLAGAVA Salro TEDL---RTEILSRTYDDLQFELSLRLVGATQRHLAITLLEDLKHRNGP----IRDYLYFLAQAYYAVGNYRRARQELLRKEPHNQQARALLDTIAEKEDGMKGLAV-LGSAAVLGVA Schco3 FDELEVLRLQYQKEITVQTKFNYAWGLVKSPIREHGVRLLQEI-YREEPLR--RRECLYYLALGHYKMGNFDEARRFLIDKEPGNMQAQSLAQLIDKGVEGYIGMAL-AGGAAAVGTL Schpo1 VDEFLQIKEQYDAEITLQTKFNLAWALVRSDSTQHGLSLFCSI-YKDSPER--RLECLYYIALSHYKLKQYEESRRYLLSKDPNSPEALKLKNRLYDAVEGYIGMVV-VAGAVALVGW Sorma AAELNVLRAQYEKEVGVQTKFNYAWGLVKSNVRADGVMLLSEI-FRTSPER--RRECLYYLALGNYKLGNYAQARKYLLENEPANLQAANLRALIDDKVEGLMGVAI-ISGVAVIGGV Sphar ---------------------------------------------------------------------------------------------------------------------- Spipu1 PQELEILRDQYLTEPRPQTKFNYAWALVRSRVRTDGIKLLHEI-YRDLPSR--RRECLYYLALGEYKLGNYRNARKYLLQLESRNNKALSLRKLIDDKVEGLVGMAI-VGAAVAAVGL Sporo1 ASELSVLRTQFEQECSTQTKFNYAWGSVKSQDKVQGVGLLMEI-YRSEPER--RRECLYFLAVGHYKLGNYPEAKRYLLEKEPNNFQSQSLSALIEKAVEGYVGIAI-AGGVATVAGL Stehi1 YDELEVLRLQYQKEVTTQTKFNYAWGLVKSPIRDHGVRILQEI-YRAEPQR--RRECLYYLALGHYKMGNYEEAKNFLLDREPTNMQAQSLGGLIEKAVEGYIGMGL-AAGAAALGTL Tapde11 PAQLEVLKKQFESEVGAQTKFNYAWGLIKSDKRSEGVKLMTDM-YKDSPER--RRECIYYLALGQFKLGNYTDARKYLLEHEPTNMQAMSLKSLIDDRVDGYIGIAI-VG---ALGSI Thetr EKELGRLEEDYEAQVSLGVATNFAHRLIASTCAEDGVDILQGMEDAMGMESM-DSESLLRLARGLFRLQRHSSARKYVLMREPNYTDAIILKRMIDDSVEGLNGVVL-LGSWAVAAGI Treme1 YDELEVLRRQYYKEVTTQSKFNYGWGLVKSPSAEMGVKLLQEI-YSASPSH--RRECTYYIAVGYYKLRNYTHARKFLLSVEPENMQAQSLRTLIERAVDAYIGVGI-LAGAAAVAGV Trire2 PSELSVLRAQFEKEVGVQTKFNYAWGLVKSNNRNDGVRLLSDI-FRVSPER--RRECLYYLALGNYKLGNYGEARRYLLDKEPANLQATDLRQLIDDKVEGLLGVAI-ISGIGVVGAF Umbra1 AESLEVLRKQYMREATIQTKFNYAWGLIKCKRTIDGVRLLTEI-YQQAPER--RRECLYYLALGHYKMSNYIEAKKFLLVHEPKNSQAIELNKLIDEKVEGVIGLAI-VGSIAAVGAM Ustma22 PSELQVLKSQYETEVTTQTKFNYAWGLVKSKQRAEGVGLLTEI-YRSDPPR--RRECLYYLSLGHYKMGNYDEARRFLIEREPNNLQAQSLNQLIEKGVEGYIGMAL-IGGAAAVASI Walse1 ASELEVLRSQYDKELSVQTSFNLAWGLVKSKKKEEGVSILSDI-YKQEPFR--RRECLYYLALGYYKVSNYQDAKKFLLSKEPNNLQARSLNQLIDRAWEGYIGLAI-GGGAVTLGAL Zygro1 PQQVEILRQQFLSEASIQSRFNYAWGLIKSMGLDDGIKLLTDI-YKESPQR--RRECLYYLTIGCYKVGEYSMAKRYLLEHEPGNHQIKALQGMVEDKIETVRGVAV-ATGVVASAAA [Cluster1931.fasta_al_trimmed; alignment length = 103] Allma1 VPRNFRLLEELEKGEKG--IGDGTISYGLAN-PDDIFMSDWNGTILGPPHSVHENRIYSLTLHCDQNYPDSAPIVKFSKVNLPTMETVLSERKLPQPPEGSTF Ashgo11 VPRSFRLLEELEKGEKG--MGPESCSYGLAD-GDDISMTHWNGTILGPPHSSHENRIYSVVIECGAEYPDRPPKVRFSRINLPNMETLLQDKKLPQPPEGSTF Aspfu1 IPRNFRLLEELEKGEKG--LGAEACSYGLAD-GEDMMMSNWNGTILGPPHSVHENRIYSVQIHCGPDYPDNPPTIQFSRVNIPTMETILLEKKLPQPPEGTNF Aurde31 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDIMMSNWNGTIIGPGHTVHENRIYSLKIYCGETYPDQPPTVSFSRVNLPSIETILVERKLPQPPEGTFF Batde5 VPRNFRLLEELEKGEKG--IGDGTISYGLAN-GEDLLMTKWHGTIIGPGHTAHENRIYSLKITCGEDYPDRPPVVSFSKVNLPTIETVLSEKKLSQPAEGTMF Botbo1 VPRNFRLLEELEKGEKG--IGDGSISYGLED-GDDIMMLKWNGTIIGPGHSVHENRIYNLKIECGHDYPDAPPEVSFSRVNLPTLETVLVDRKLPQPPEGSTY Botci1 VPRNFRLLEELEKGEKG--LGADACSYGLTD-GDDLYMSNWNGTILGPPHSVHENRIYSLTMHCGENYPDVPPTIKFNKINLPTMETALTEKKLPQPQEGSTY Caeel VPRNFRLLEELEEGQKG--KGDGNISWGLED-DSDMTLTRWTASIIGPPRTPYESRIYNLQIQCGGNYPREPPTVRFTKVHMVMIKTVLEDLKLQQPAEGAMF Canalb1 IPRNFKLLEELEKGEKG--LGAESISYGLTN-QDDITMTYWNGTILGPPHSNHENRIYSLNIICDESYPDKPPIVTFSKINLPTMETILLEKKLQQPPEGSTY Cangl VPRSFRLLEELEKGEKG--LGPESCSYGLAD-ADDITMTRWNGTILGPPHSNHENRIYSVSIECGPKYPDEPPTITFSKINLPNMETILLDKKLVQPEEGSTF Capow VPRNFRLLEELDKGEKG--IGDGTISYGLQN-GEDMELSNWMGTILGPPRTVFENRIYSLKLHCGPKYPEEPPTVRFTRINLNTMETVLSEMKSSQPPEGTDF Catan2 VPRNFRLLEELEKGEKG--IGDGTISYGLAN-PEDILMSDWNGTILGPPHTVHENRIYSLKIHCDANYPDSPPTVSFSKVNLPTLETVLSEKKLVQPPEGSTF Cioin -PRNFVLLEELDEGIQG--GGGGKVSWGLEN-QCDSSLTYWRGTIIGPAKTKFENRIYTLRVTCGEDYPKKPPSIRFTRINLTRIKHVLTEAKLSQPPEGSSY CocheC53 VPRNFRLLEELEKGEKG--LGAEACSYGLDN-GDDLLMSDWNGTILGPPHSVHENRIYSVSIHCGPEYPDAPPDIKFSKINLPTMETILIEKKLPQPPEGTTF Coere1 VPRNFRLLEELEQGEKA--TSAGYCSYGLAD-LEDSLMYNWTALILGPLNTPFENRLYQVLLRCDENYPKVAPKVWFTQINMPTIHMVLEAR-LPQPDKNSTY Conco1 VPRNFRLLEELEKGEKG--IGGGVCSYGLAD-GDDITMSNWNGTIIGPLHTVHENRIYSLKIHCDEQYPDRPPLVSFSKINLTTLETVLTEKKTPQPPEGTLF Conpu1 IPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDIMMSHWNGTVIGPGHTVHENRIYSLKITCGDNYPDEPPVIQFSRVNLPTMETVLVERKLPQPPEGSTF Copci LPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDIMMSNWNGTIIGPGHTVHENRIYSLKITCGENYPDSPPDVQFSKINLPSIETVLVERKLPQPPEGSMF Croqu1 VPRNFRLLEELEKGEKG--LGDGTCSYGLAD-GDDITMTQWNGTIIGPSHSVHENRIYDIKITCDNSYPDKPPTIYFTKINMPTLETLLVERKLPQPPEGTKF CryneH991 VPRSFRLLSELEHGEKG--IGDGSCSYGLKD-SDDIAMYEWNGTILGPPHSAFENRIFSLSIYCGDNYPDVPPLVKFSRISLPTLETVLVERKSSQPPEGVDF Crypa2 VPRNFKLLEELEKGEKG--LSNGTCSYGLED-QEDISLTNWRGTIMGPPHGHFENRIYELKIVCGPEYPKQPPVIHFTQINLPSIEAALSAKKLPQPPEGTKY Debha1 IPRNFKLLEELEKGEKG--LGAESISYGLTN-QDDITMTYWNGTILGPPHSTHENRIYSLTIVCDQSYPEKPPKVQFSKINLPSMETVLLEKKLAQPTEGTTY Dekbr2 IPRNFKLSEELEKGEKG--LGAESCSYGLSD-PEDMTSTHWNATILGPPNSVHENRIYSLHIECGQSYPDKPPSVRFSKINLPSMEIILLERKIPQPPEGETY Dicdi IPRNFVLLEELESGEKS--TGDGTISYGLES-PDDILLSSWIGTIIGPQNTPFDNRFYSLKLYCDKDYPNKPPTVRFTKINIGRIQNILSEKKLVQPPEGANF Dmel -----------------------------------MTLTYWIGMIIGPPRTPFENRMYSLKIECGERYPDEPPTLRFTKVNINNIKTMLQELKLAQPPEGSCF Enthi KPRFAVLLEDCENGQHG---NLTFVSYFLQN-EDDTSLSNWNGEFLFKDGSS-----LSFTVKCSEQYPAEVPEITFSKIQFNALFTLIHD------------ Falba -------MDELERGEKA--ASFQSYSYGLSD-AEDITLTNWHATIIGPNGTTFDNRIYSLSIVCGPEYPNSAPVVSFTMINASTIESVLKARSNKQPAESAVY Fomme1 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDILMSNWTGTIIGPGHTIHENRIYSLKITCGEDYPEMPPSVRFSRVNLPSIETVLVERKLPQPPEGSFF Fusgr1 VPRNFRLLEELEKGEKG--LGAEACSYGLED-PEDLLMSSWNGTILGPPHSVHENRIYSVKMHCGPDYPDLPPTIQFSQVNLPTMETVLIEKKIPQPPEGSTY Galma1 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDILMSNWNGTIIGPGHTVHENRIYSLKITCGPSYPDARPDVEFSRVNLPSIENVLVERKLPQPPEGTTF Ganpr1 VPRNFRLLEELEKGEKG--IGDGTISYGLAD-PDDSILTTWNGTIIGPLNTVHENRIHSVKITCGPQYPDKAPSVQFSRINMPTIETVLSERKLPQPPEGSTY Gloin1 VPRNFKLLEELEKGEKG--IGDGTCSYGLSN-GEDIFMSDWNGTIIGPPGTIHENRIYSLKLYCDDNYPNNPPIVHFSRINLPSLEDILVDKKLPQPPEGSTF Hisca1 VPRSFRLLEELENGEKG--RGAEACSYGLAN-GDDVKMTNWNGTILGPPHSVHENRIYSVNIKCGENYPDLPPTIHFSKVNLPTMETILLEKKIPQPPEGSNF Klula1 VPRSFRLLEELEKGEKG--LGPESCSYGLSD-SDDITMTKWNGTILGPPHSNHENRIYSVLIECGPSYPDEPPKVKFSKINLPTMETVLLEKKLLQPQEGTTF Lacbi2 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDIMMSNWNGTIIGPGHTVHENRIYNLKITCGNSYPDVHPDVQFSRVNLPSIENVLVERKLPQPPEGSTF Lenti61 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDIMMSHWNGTIIGPGHTVHENRIYSLRITCGEHYPEQPPTVQFSRVNLPSIETVLVERKLPQPPEGSMF Malgl1 ------------------------------------VMTNWNATILGPANSVHENRIYSLRLVCGDSYPQVPPEIWFTKINLPTMESLLAERKLAQPPEGTTY Mellp23 ----------LEKGEKG--LGDGTCSYGLAD-GDDITMTKWNGTIIGPSHSVHENRIYDIKITCGNFYPDKPPTIHFTKINMPTLETVLVERKLPQPPEGTMF Mnele VPRNFKLLQELEDGEKG--VGDGSLSWGLEK-DDDMTLTHWNATIIGPPRCPFENRIYQLHIEAGPDYPDCPPKIRFTRIIVNTIKDALKSRK---------- Monbr VPRNFHLLEELQEGEKGGRDDDGTVSWGLEQ-DDDIELQHWRGMIIGPPRTPFEMRIYELKIFCGPRYPDLPPEVYFSQIHMDTIKSVLQDLKLKQPAEGSAY Morel2 IPRNFKLMEELEKGEKG--IGDGTCSYGLKD-GDDMLMSNWNGTILGPGHSVHENRIYSLSLYCGDHYPDVPPTVSFSRINLPGLETVLTERKLPQPPEGTFY Mucci2 VPRNFRLLEELEKGEKG--LGDGACSYGLAD--DDLLMHNWHATILGAPHSVHENRIYSLTVFCGDQYPNQPPVLQFSRINLPTLETVLTERKLPQPAEGSTY Mydma VPRNFRLLEELEEGQKG---GDGTVSWGLES-DDDVDLVRWTGMILGPPRTCYENRIYNLNIRCGSKYPHERPTCTFTKINMTTIKTLLTEAKLAQPPEGSKY Neucr2 VPRNFKLLAELEKGEKG--MGAGACSYGLED-PEDILMTHWTGTIWGPPHGNHENRIYELKMECGANYPKEPPVIHFSQINLPSLEAALIAKKLPQPPEGSKY Orpsp11 ------------------------------------------------------------------------------------------------------- Pench1 VPRNFRLLEELEKGEKG--LSADACSYGLAD-GEDMMMSNWNGTILGPPHSVHENRIYSVNIHCGPDYPDNPPTIQFSRVNIPTMETVLIEKKLPQPPEGSTF Phybl2 VPRNFRLLEELEKGEKG--IGDGNCSYGLAD--DDLLMHKWHATILGPPVSVHENRIYSLKIYCGEDYPDQPPSVQFSRINLPTIETILLERKLPQPPEGSSF Picst3 IPRNFKLLEELEKGEKG--LGAESISYGLDN-QDDITMTYWNGTILGPPHSSLENRIFSLKIVCDETYPDKPPKVTFTLINLPSIETVLLEKKLTQPEEGTLF Plicr1 VPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDMLMSQWNGTIIGPGHTVHENRIYSLKIVCGESYPDQPPTVQFSRVNLPSIETVLVERKLPQPPEGTTF Polpo LPRNFRLLAELEKGEKG--LGDGSVSYGLES-PEDTYLSSWIGTIIGPN-----------QIFCDKDYPNKPPSVKFSKINIPTIETILLERRLQQPPEGTYF Pucgr2 VPRNFRLLEELEKGEKG--LGDGTCSYGLAD-GDDITMTKWNGTIIGPSNSFHENRIYDIKITCGDSYPDFPPTIFFTKINLPTLETVLVERKLIQPPEGTMF Punst1 VPRNFRLLEELEKGEKG--IGDGSCSYGLEDNGDDMTMSDWNGTIIGPGHTVHENRIYSLKIYCGPEYPDRPPTIQFSRVNLPSIETVLVERKLPQPPEGSTF Rhior3 VPRNFRLLEELEKGEKG--LGDGACSYGLAD--DDLLMHNWHATILGAPHSAHENRIYSLTVYCGDNYPNQPPSFQFSRINLPTLETVLTERKLPQPPEGTTF Rhoto1 VPRSFRLLEELEKGEKG--IGDGTCSYGLQD-GEEMSMEKWNGTIIGPGHTVHENRIYSLSIRCGPQYPDVPPEITFTRINLPTLETVLVERKLNQPAEGTTF Rozal11 VPRNFRLLEELEKGEKG--IGDGTISYGLAN-SDDMMMRDWNGTIIGPQMTVHEFRIYSLKILCGDNYPDAPPEISFSKINLNTIETVLTERKLVQPAEGTTF Sacce1 VPRNFRLLEELEKGEKG--FGPESCSYGLAD-SDDITMTKWNGTILGPPHSNHENRIYSLSIDCGPNYPDSPPKVTFSKINLPTMETLLLDKKLRQPKEGETF Salro VPRNFHLLAELESGEKG--HGNGMVTWGLDR-DDDPLLHYWRGMIIGLDHTVFQENMYSVKIYCSDAYPDVPPQITFTPIKMDTMYDALQDRKTKQP------ Schco3 IPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDMMMSKWNGTIIGPGHTVHENRIYSLKITCGDEYPNKPPQVQFSRVNLPSIESILVERKLPQPPEGSMF Schpo1 VPRNFKLLEELEKGEKG--LGESSCSYGLTN-ADDITLSDWNATILGPAHSVHENRIYSLKIHCDANYPDAPPIVTFSRINLPSMETVLLDRKLPQPPEGSTF Sorma VPRNFKLLAELEKGEKG--MGAGACSYGLED-PEDILMTHWTGTIWGPPHGHHENRIYELKMECGPNYPKEPPIIHFSQINLPSLEAALIAKKLPQPPEGSKY Sphar VPRNFVLLDELEKGEKG--IGDGSISYGLDG-DDFSTMTSWNGTILGRPSSAFENRIYSLKIHCGPEYPDKPPTVRFTKVNLKRMEDTLKEAKLSQPAEGTMY Spipu1 VPRNFRLLEELEKGEKG--IGDGTISYGLAD-GEDTMMSNWNGTIIGPGHTVHENRIYSLRIFCGPEYPDRPPTVSFSRINLPTIETVLAEKKLSQPPEGSTF Sporo1 VPRSFRLLEELEKGEKG--IGDGTCSYGLQD-GEEMSMERWNGTIIGPGHTVHENRIYSLSIYCGPSYPDSPPEITFTRINLPTLETILVERKLPQPAEGASF Stehi1 IPRNFRLLEELEKGEKG--IGDGSCSYGLED-GDDILMSHWNGTIIGPGHTVHENRIYSLKITCGETYPDRPPTVQFSRVNLPSIETVLVERKLPQPAEGSTF Tapde11 IPRNFRLLEELEKGEKG---GDGACSYGLAD-EADIMMSDWNGTILGPAHSVHENRIYSLRITCGPTYPDHPPVLQFSRINLPTMETILQEKQFQQEASSTPG Thetr ------------------------------------------------------------------------------------------------------- Treme1 VPRSFRLLSELEHGEKG--IGDGSCSYGLKD-GDDLAMYEWNGTILGPPHSSYENRIFSLSIYCGDKYPDLPPLVKFSKVNLPTLETILVERKNPQPLEGAEY Trire2 VPRNFRLLEELEKGEKG--LGAEACSYGLED-GEDLLMSNWNGTILGPPHSAHENRIYSLKMHCGEKYPDEPPTIQFSQINLPTMETILIEKKIPQPPEGSTY Umbra1 VPRNFRLLEELEKGEKG--IGDGTCSYGLAD--DDILMHNWHATILGPGHSVHENRIYSLKVICGERYPNEPPQVQFSKINLPTLETVLTDRPKALPFNTSIM Ustma22 VPRNFRLLEELEKGEKG--IGDGSCSYGLDD-GSDLMMSNWNATIIGPGHSVYQNRIYSLSIHCGPNYPDRPPEVKFTKINLPTIEAILLSRKLPQPAEGAAY Walse1 TPRNFRLLEELEKGEKG--IGDGSISYGLSD-SDDISMTNWNATIIGPGHSTHENRIYTLSVECQKEYPTKPPLLKFSKINLPTIEKVLLDRKLPQPKEGEYF Zygro1 VPRSFRLLEELEKGEKG--LGPESCSYGLAD-SDDISMTTWNGTILGPPHSNHENRIYSLSIECGPNYPDHPPTIKFSKINLPNMETILLEKKLPQPKEGSTF [Cluster1933.fasta_al_trimmed; alignment length = 136] Allma1 GNMALLPVK--SKTR-GYALNLFRANLFRNFEIQ-GPADRVLIYLILFISDCLSKLNDASRTLVTLAVG-S-FAMPGDGFPLNALYAPPSMVEKENLRAYMTQLRQEMVSRLLD-RLYPSKWWMAFSKRKFMNKSL Ashgo11 GNFVLLPLN--TRFR-GPALDLFRANFFKNFEIK-SPADRVLVYGILFTNSCLGQLNEAVKALTNLALD-S-FTLPGTGFPLNNVYSVPDGAQMELLKGYLQQLRQELATRLLD-RVYPSKFWLAFTRRKFMNKAL Aspfu1 GNFPVLPLR--TRTR-GPALSLFRANLFRNFEIN-GPADRMLIYGTLFISECLGKVREAEKALINVSLD-H-FAIPGDAFPLNQAFEPPDRQDAETLRQYLSQVRQEIAIRLHA-RLYPSKWWLSFAKRKFMGKSL Aurde31 GNVSILPIK--TRIR-GPALDLFRANLFRNFEIK-GPADRLLIILILFVSDCLAKILEAGKLLNTLAVD-N-FPVPGENFALNAHYAPPNRNESDYLRQYLVQTRQELAARLVE-RLYPSKWWMSFTKRRFMNRSL Batde5 GNMSMLPFK--TKSR-GPAISLYRANFFRNFEIK-GGADRVLIYIMLYIQECLGKLIEGQKVLATHAVQ-N-FAIPGDNFPLNAMYEKPTRPDADLMKQYLTQLRQEVSLRLVL-RVYPSKWWMCFSKRKFMNLPG Botbo1 GNMSILPIK--TRIR-GPALDLFRANLFRNFEIK-GPADRLLIVLILFISDCLAKVNEATKTLNTLAVD-Q-FPLPGDMFPLNAHYAAPNRVEADYLRQYLVQTRQELAARLVD-RLYPSKWWLSFTKRRFMNRSL Botci1 GNFPLLPLR--TKVR-GPALSLFRANFFRNFEIQ-GPPDRLLIYGILWVSECIGKVREAQKEVQNIALDSN-FAIPGEGFPLNQMFEAPSRQEAETLRQYLGQVRQELASRLLA-RIYPSKWWLSFTKRKFMGKSL Caeel TNMGKLPIR--TNFK-GPALTYFKPNFFREFEIK-GPADRTMIYLIFYITECLRKLIAGQKDLHALALS-HLLPIPGEGFPLNSMYKAPSKPDEDEMRAYLQQIRQEIGARLCD-LAFPSKWWLCFARRRFMDKGL Canalb1 GNLSLLPFH--TNFR-GPILDLFRANFFKNFEIK-GNSDRLLIYGILFINQCLTKLKEATKILINLSVD-N-FHLPGDGFPLNSLYVSPNKSEYELLKNYLTQFRQELSDRLIK-RIYPSKHWLAFTKRKFMNKSL Cangl GNLVLLPLN--TKFR-GPALDLFRANFFKNFEIK-TNSDRLLIYGILYINDCLNHLNEAIKVLTNLALD-D-FSLPGTGFPLNSVYSIPDHNAMELLKSYLQQFRQELASRLIE-RIYPSKFWLAFTRRKFMNKSL Capow GNFAFLPLN--SSVK-GPALKYFKANFFKNFDIK-GNADRVLIYLTLYITDCLQKLNDGLKAMNTMSLE-T-FSLPGDNFPLNGLYQLPARADADTMRQYITQLRQEIGIRLCE-RVYADKWWMCFQKRRFLNKSL Catan2 GNLALLP------------LNYFLVSLFRNFEIQ-GPADRVLIYLILFISECLSKLDEATRALTTLALS-Q-FSIPGEGFPLNALYAAPSRVDADNMRTYMTQLRQEVVSRLLE-KLYPSKWWMAFAKRKFMNKSL Cioin GNLALVPIKCPTKYK-GPAIGFFRANFFRNYDIK-SDADRTLIYITLYIQECLKKLEQGRKELYTLAVS-P-YDIPGDGFPLNAMYSKPSRAEADQMKAYIGQLRLEIGDRLLE-KVIPSKWWMCYSKRKFMEKSL CocheC53 GNFALLPLR--TRTR-GPALALFRANFFRNFEIK-GPADRVLIYGILYVSEVLGKIREAEKAVMNSALDTN-FAIPGDGFPLNQAFEAPDRNSAEVLRQYIMQMRQELATRLLN-RVYPSKWWLSYTKRKFMGKAL Coere1 NGIPLLPLA--SQVK-GASLELFRPNYFKNFEIK-GNGDRLLIYVILFISQSLNKLSEAAKILHTLAVT-N-IVIPADGFPLRSVY--PDKMEGDQLRQYLQQVRLAVVQRLVP-IVYPSKWWLCFQKRHFMGKTM Conco1 GNMSLLPLN--TNVR-GPAIELFRANLFKNYEIK-GGADRVLIYVTLFISEILTTLGEATKILNNLALE-R-FTIPGDNFPLNSMYHPPNRNEADLLRQYVGQLRQETVLRMHK-NLYPSKWWMMFAKRKFMGKSL Conpu1 GNVAVLPIR--TKVR-GPALDLFRANLFRNFEIK-GPADRLLIVLILYVSDCLAKLIEASKSLNTLSVD-N-FPIPGDNFALNAHYSPPSRQDADYLRQYLTQVRQELSARLVE-KLYPSKWWMSFQKRRFMNRSL Copci GNMSILPIR--TRIR-GPALDLFRANLFRNFEIK-GPADRTLIILILFVSDCLAKIIEASKLLNTLSVD-H-FPIPGDNFALNSHYAPPSRQEADYLRQYLTQVRQELSARLVE-KLYPSKWWMAFQKRRFMNRSL Croqu1 ANMVILPVR--TKIR-GPALDLFKSNLFRNFEIK-GLADRVLIYLILFISDCLNKISEASKQLLSYSLD-N-FYLPGEGFPMNGIYAPPDKIEADLLRQYLTQIRQECAVRLVE-KVYPSKWWMCFQKRKFMGKSL CryneH991 GNTAILPIT--TKIR-GPALDLFRANLFRNFEIK-GPADRLLIYLILFISDCLTKLQEATKVLQTLSVD-N-FALPGDGFPLNSLYHPPSRVDADHLRSYLTQTRCELALRLCD-RIYPSKWWMSFQKRRFMGRSL Crypa2 GNFPLLPLR--TKTR-GPALSLFRANFFRNFEIQ-GNADRLLIYGILFVSECLTKIRTAGKDVMNLALDTN-FAVPGDAFPLNQMYEPPDRQDAEQLRQYMSQVRQELATRLLA-RVYPSKWWLSFTKRKFMGKAL Debha1 GNIALLPIH--TKFR-GPSLDLFRANFFKNFEIK-GPADRLLIYGILFVSDCLSKLKEATRILNNLSLD-S-FSLPGDGFPLNSMYQPPNKNEADLLRSYLQQFRQELAERLLK-RIYPSKFWLAFTRRRFMNKSL Dekbr2 GDFAVLPLK--TKFK-GPSLDLFRANFFKNFQIK-GPADRTLIYGILFVSQCLNKLSESVRVLLNLASE-D-FAIPGDGFPLNSLYQAPDRNESIFFRQYLTQFRQELAMRLIE-RLYPNKFWMAFSRKKFMNKSL Dicdi GNVPILPLK--TTHK-GPALDLFKANLFRNFEVQ-GNGDRVLIYLTLYITKCLLKIADAEKALFLIAQE-Q-FSIPGEAFPLGGLVTVPTRDAADTLRQYFTQLRLELGVRLCQ-RVYANKWWICFSKRKFLNKAL Dmel GNMAILPLR--TQVR-GPALYYFKANFFRTYEIK-SDVDRVLIYVTLYITECLKKLAQGQQDMYSLAIS-K-FDIPGDGFPLNAVYAKPTAQDADLMRQYLLQLRHETGNRVLE-KVFPNKWWTCFAKKKFMEKSL Enthi GNFPLMQFK--TKVKVNPKITYYKANFYKNFDMSICEADKLLVYLIFYIQSLLLKFVECDKMAYSLAIE-N-FALPGDKFCLGGIVEPLKASEKEVVRQYMTAIRNETGLRLTQ-AVFCDKWWMCFNKRKFLNKTI Falba GNFPLLPLT--TSSR-GPAISIFRANFYRNFEFQ-GNADRALCWIILYISDCLNIIIDANKRLLTAAADAN-FAIPGDNFVFGALYQKPSPSDANLLRQYMSQLRHEVGTRLVS-IVYPSKWWMCFTRRKFMNKSL Fomme1 GNMSILPIR--TKIR-GPALDLFRANLFRNFEIK-GPADRLLIVLILFVSDCLAKIIEAGKSLNTLAVD-N-FSIPGDGFPLNAHYAPPSRADADYLRGYLVQTRQELAARVVE-RLYPSKWWLSFQKRRFMNRSL Fusgr1 GNFPLLPLR--TKTR-GPALALFRANFFRNFEIQ-GPADRLLVYGIWFVSDCLTKIRDAQKDVMNLALDLN-FAIPGDGWPLNQMYEAPDRQEAEQLKQYMSQVRQELAARLLA-RVYPSKWWLSFTKRKFMGKSL Galma1 GNMSILPIR--TRIR-GPALDLFRANLFRNFEIK-GPADRTLIVLILFISDCLAKLIEASKLLNTLSVD-T-FPIPGDNFPLNSHYAPPSRAEADYLRQYLIQVRQELAARLVE-KLYPSKWWMSFQKRRFMNRSL Ganpr1 GNLAVLPLK--TKSR-GPAFNLYRANLFRNFEVK-GSCDRVLIYLTIFIGECLSKLQDALKLLNTHALQ-S-FSLPGDSFPVNAFIARPNSAEADNMKAYLGQLRQEVAIRLPQ-RIYPSKWWLAFSKRKFMNITK Gloin1 GNMVLLPIK--TKIK-GPALDLFRANFFRNFEIQ-GNADRVLIYLILFISDCLSRLKDALKILNTRALD-H-FALPGDNFPLNALYAAP-RGEADVLRQYLTQVRQELANRLVE-RVYPSKWWMSFQKRKFMNKSL Hisca1 GNFPLLPLR--TRTR-GPALSLYRANFFRNFEIK-GPADRMLIYGILFISECLTKVREAEKVLINTSLD-H-FAIPGDSFPLNQAFEPPDRQDAETLRQYISQVRQELALRLHS-RLYPSKWWLAFAKRKFMGKHL Klula1 GNFALLPLN--TKYR-GPALDLFRANFFKNFEIK-SPADRILIYGILFINDCLANLNEAVKKLMNLGLD-S-FAIPGTGFPLNTVYSIPNPADVELLKSYIQQFRQELAMRLLE-RVYPSKFWLAFTRRRFMNKSL Lacbi2 GNMAILPIR--TRIR-GPALDLFRANLFRNFEIK-GPADRTLIVLILFISDCLAKLIEASKSLNTLSVD-S-FPIPGDQFPLNAHYASPSRADADYLRQYLTQVRQELAARLIE-KLYPSKWWMSFQKRRFMNRSL Lenti61 GNLSILPIK--SKFR-GPALDLFRANLFRNFEIK-GPADRLLIILILFVSDCLAKIIEATKLLNTLAVD-N-FPIPGDNFALNAHYAPPNRADAEYLRSYLTQVRQELAQRLVE-RLYPSKWWMSFQKRRFMNRSL Malgl1 AGAAILPLN--SKIR-GPAIDLFRANLFRNFEIK-GAADRTLIYLILFISDCLSRINEAYKHLSSYAVD-A-FALPGDQFPLSTLYSLPSRADADALRQYLTQARQETVSRLLD-KIYPSRWWLAFSKRKFMGKSL Mellp23 --MVILPVR--TKIR-GPALDLFKSNLFRNFEIK-GLADRVLIYLILFISDCLNKISEASKQLLSYSLD-N-FYLPGEGFPMNGIYAPPDKIDADLLRQYLTQIRQECSLRLVE-KVFPSKWWMCFQKRKFMGKSL Mnele GNIAFLPLR--TTVK-GPALNFFKANFFKNYEIK-GTADRLLIYLTLYATDCIVKLNQALKDMYSLAIS-R-FSLPGEGFPLNAVYAKPG-NDVEKMRSYLTQCRQELGQRMVE-KVFPSKWWTCFSRRKFMDKTL Monbr GGVALLPFHA-HHTR-GPALKFFKANFFQSYEVR-GPADLLLIYLTLYTHQCIMRVDGAQRALFQLAQE-N-FSLPCDGFQLSSYYQPLSKSDGDELRAYLKQCREELGNRLAE-RCCPSKWWVCFAKRKFLGKSL Morel2 GSMALLPIK--TRVR-GPALNLFRANLFRNFEIK-GDADRVLIYLILFITECLGKLREAEKILGTLALG-N-FAIPGDTFPLNALYTAPNKMDADLLRQYVSQLRQEMAVRLPN-RIYPGKWWMCFQKRKFMNKSL Mucci2 GNMFLLPIK--TKFR-GNALDLFRANLFRNFEIK-GNADRVLIYLILFISQCLGSIGEALKTLNTLAVS-N-FAIPSDAFPLNAMYQAPDKFQTEQMKQYMQQLRQELVVRLVD-RIYPSKWWMCFSKRKFMNLSL Mydma CKMALLPLN--TKFK-GPALQFFKANFFKNYEIK-TPADRVLIYLTLYVTECLKKLEEAKKEMATLAIL-N-FDIPGDKFPLNALYGKPDKNEADQVRAYFLQLRQELGQRLIE-KVYPSKWWMCFVKRRFMDKSL Neucr2 GNFPLFPLR--TKIR-GPILALFRANFFRNFEIQ-GPADRLLVYGIWYISDCLGRIREATKEVNNAALDVN-FALPGDGWPLNQMYEPPDRQDAEVLRQYLSQVRQELAQRLLA-RVYPSKWWLSFTKRKFMGKGL Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------- Pench1 GNFPILPLR--TRTR-GPALSLFRANLFRNFEIN-GPADRMLIYGTLFISDCLGKVRDAEKALTNAALD-S-FAIPGDSFPLNQAFEPPDRQDAETLRQYISQVRQEIAIRLHA-RLYPSKFWLSFTKRKFMGKSL Phybl2 GNMFVLPIK--TNSR-NNAIQLFRANLFRNFEIK-GNADRVLIYLILFISECLGKLGDALKQLSTLAVS-S-FSIPGDGFPLNAMYAPPDRYQADQMKQYIQKLRQELAIRLVE-QIYPSKWWMCFQKRKFMNLSL Picst3 GNIVLLPIH--SKFR-GPALDLFRANFFKNFDIN-GPADRLLIYGILFVSDCLSKLKEAVKVLNNLSLD-S-FSLPGDGFPLNSYFQPPNRNEADLLRSYLQQFRQELADRLLS-RIYPSKYWLAFTKRRFMNTSL Plicr1 GNMAILPIK--TRIR-GPAIDLFRANLFRNFEIK-GPADRLLIVLILFISDCLAKIIEATKSLNTLSVD-S-FPIPGDNFPLNAHYAAPSRADAEYLRQYLTQVRQELAARLVE-RLYPSKWWMSFQKRRFMNRSL Polpo ---------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ANMVILPIR--SKIR-GPALDLFKSNLFRNFEIK-GFADRVLIYLILFISDCLHRINEASKQLLSYSLD-N-FFLPGEGFPMNGIYAPPDKIDADLLKQYLTQIRQECSLRLIE-KVYPSKWWMCFQKRKFMGKSL Punst1 GNVAILPIK--TRIR-GPALDLFRANLFRNFEIK-GPADRLLIILILYVSDCIAKLIDAGKMLNTLSVD-S-FPIPGDNFVLNAHYAPPSRVDADYLRQYLTQVRQELAARLVE-RLYPSKWWMSFSKRRFMHRAL Rhior3 ---------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 GNFPLLPFR--SSIR-GPALQLFRANLFRNFEIK-TPADRALIYLILFIGDCLGRIQDALKQLTTHSLS-H-FSLPGEGFPLNQVFTPPTPVEKDALRSWLVQARQETVVRLLERHVYPSKWWMAFSKRAFMNKRL Rozal11 GSMAILPVK--TK-K-GMALALFRANFFRNFEIQ-GDADRVLIYLILFISECLNKINDGQKILGALGLENN-FVVPGDGFPLAALYSTPNRNEADTLRQYIGQLRQELVNRLIP-ILYPSKWWMSFQKRKFMNKSF Sacce1 GNFALLPLN--TKFR-GPALDLFRANFFKNFEIK-SPADRVLIYGILFINDCLAHLNEAVKVLTNVALD-N-FTLPGTGFPLNNVYQVPDHNSMDLLKTYIQQFRQELAMRLLE-RVYPSKFWLAFTRRRFMNKSL Salro GGIPLLPIHA-RNSK-GPAIRFFRANFFASYKID-AAPDRLMVYLTLFCHQCVMRLDDAAREMYQLGIE-N-FTLPTDGFQLKGFFEKLQKSSQDKLRAYLQQCRQELSARMAE-VVLPSKWWTCFAKRKFLGKAL Schco3 GNMACLPIK--TRIR-GPALDLFRANLFRNFEIK-GPADRELIVLILFVSDCLAKLIEAQKLLNTLAVD-Q-FAIPGDGFPLNAHYAPPGRSDAEFLRQYLTQVRQELALRLIE-RLYPSKWWMSFQKRRFMHRAL Schpo1 GNIAMLPLK--TKFR-GPAIGLFRANFFRNFEIK-GPADRTLIYGTLFISECLGRVRDAERQLNSLALE-N-FSIPGSGFPLNALYAPPSPQDAEIMRTYLTQFRQELAYRLLS-HVYPSKWWTCFSKRRFMNKAL Sorma GNFPLLPLR--TKIR-GPTLALFRANFFRNFEIQ-GPADRLLVYGIWFISDCLSRIREATKEVNNAALDVN-FALPGDGWPLNQMYEPPDRQDAEILRQYMSQARQELAQRLLA-RVYPSKWWLSFTKRKFMGKGL Sphar ----ILIINC---------FNYFKPNFFSSFEIE-GTADRVLIYLTLFIRECIVKSKEAEKTLNTFALS-N-FSMPGDHFTLGTMYPAPDKGEADLLKQYITQLRVETAQRFVK-KAFPDKWWFCFAKRKFLNKTI Spipu1 GNMALLPIK--TKIR-GPAIALFRANFFRNFEIK-GTADRVLIYLLLFIQESLGKLLEGQRTLQTHALQ-N-FAIPGEGFPLNAMYEKPNRNDADTLRQYLSQLRQECATRLVV-KVYPSKWWMCFSKRKFMGLPN Sporo1 --LSLLPFS--SSIR-GPALQLFRANLFRNFEIA-GNADRVLIYLILFTGDCLAKIQEAQKHLTTYAID-H-FSLPGEGFPMNNVMTGPDRVSADALRQYLLHARQELVLRLVQ-QVYPSKWWLSFQRRRFMGKSL Stehi1 -------------------LDLFRANLFRNFEIK-GPADRLLIILILFISDCLAKLIEASKLLNTLAVD-S-FPIPGDNFQLNAHYAPPSRADADYLRQYLVQVRQELAARLIE-RLYPSKWWMSFQKRRFMNRSL Tapde11 GNFALLPLK--TRYK-GPSLELFRANFFRNFTID-GPSDRTLIYGILFISDCLARLNEAVKIVNTLALE-S-FAIPGEGFPLNNVYAAPSRPDADLLRQYLTQFRQELAQRVVA-RVYPDKFWLAFTKRKFMGKTL Thetr CSCSILPLR--SEVR-GPALRYWKANFFKNYDIQ-GPADRVLIYLTLYVSQCLKELKDGVKALYTLSLS-N-FNIPGDQFELGGFFSAPSRAEADEIRAYFTQLRQELGIRLVD-LVYASKWWMCFKSRKFLNIAL Treme1 GNTAILPIN--TKIR-GPALDLFRANLFRNFEIK-GPADRLLIYLILFISECLTKLQEAIKQLSTLAVD-N-FALPGDGFPLNSLYHPPSRVDADALRSYLTQTRSELAVRLCD-RLYPSKWWMAFQKRRFMGRSL Trire2 GNFPLLPLR--TKTR-GPALRLFRANFFRNFEIK-GPADRLLVYGIWFVSDCLQRIREASKEVNNLALDLN-FAIPGDGFPLNQMYEPPDRQEAEQLKLYMAQVRQELASRLLA-RVYPSKWWLSFAKRKFMGKSL Umbra1 GNFFILPIK--TKVR-GNALNLFRANLFRNFEIK-GNADRVLIYLILFISECLGKLGDAVKQLSTLAVT-N-FAIPGDTFPLNAMYSHPDRGQADQLRIYIQQLRQEMAVRLVD-RVYPSKWWMCFQKRKFMGLSL Ustma22 GSMSVLPIR--SRTR-GPAIDLFRANLFRNFEIK-GPADRVLIYLILFISDCLTKINEAQKQLATYSVD-S-FALPGDNFPLNSLYAPPSRADADALRSYLTQVRQETAARLVD-KVFPSKWWLAFTKRRFMGKSL Walse1 GNTSILPFK--SQYR-GVAILLFRANLFRNFEIK-GGADRLLIYLILFISDCIAKLNEASKQLHTLAVD-S-FALPGEGFPLNSLYAPASRMDGDYLRSYLTQARVETVNRLIP-IFYPSKWWMAFNKRKFMGKSL Zygro1 GNFVILPLN--TKYR-GPALDLFRANFFKNFEIK-SPADRVLIYGILFVNEVLAHLNEAVKIATNVALD-S-FTIPGTGFPLNTVYSVPDHNAMELLRTYIQQFRQELAMRLLE-RLYPSKFWLAFTKRRFMNKTL [Cluster1943.fasta_al_trimmed; alignment length = 54] Allma1 RPFDLIKLNLDEMVQVKLRGNRELVGKLHAYDQHMNMVLGNVTESVTVIMLFVR Ashgo11 TPLDLLRLNLDERVYVKLRGARKLSGTLQAFDSHCNIVLSDAEETIYQLMVFVR Aspfu1 EPLDLVRLSLDEIVFVKLRGDRELKGRLHAYDSHCNLVLGDVEETIYVV----- Aurde31 EPFDLIRLSLNERVFVKLRGDRELTGVLHAYDGHMNMIMSDVEETIMIVMLFVR Batde5 EPLDLVRLSLDERIYVKMRGDRELRGKLHAYDQHMNMVLGEVEESITVVMLFVR Botbo1 EPFDLIRLSLSERVFVKLRGDRQLTGVLHAYDGHMNLIMSDVEETIMIVMLFVR Botci1 EPLDL------------------------AYDSHCNLVLGDVVETIYVVMLFVR Caeel EPLDLLRLSLDERVYVKMRNDRELRGRLRAFDQHLNMVLSEVEETITTRMLFVR Canalb1 QPLDLIRFQLDEYVLVKLRGARELKGKLQGYDSHCNMVLSDAEETIYTSMVFVR Cangl TPLDLLKLNLDERVYVKLRGARAMEGVLQAFDSHCNIVLSDAVETIYELMIFVR Capow VPLDLIKLSLDERILVKMRGDRELRGRLHAYDQHLNMILSDVEETVTTVMLFVR Catan2 LPIDLIKLALDEPVLVKLRGNRILKGKLHAYDEHLNMILGNVTESITSVMLFVR Cioin ------------------------------------------------------ CocheC53 EPLDLVRLCIDEIVILKLRGDRELKGRLHAYDSHCNLVLGDVEETIYIAMLFIR Coere1 EPLDLVRLRLDEEVYLKLRGDRELCGRLHAYDQHLNMVLGNVQETITIVMLFVR Conco1 QPLDLVRLSLDERIYVKMRGDRELRGVLHAYDQHMNMILGEVEEIATIVMMYVR Conpu1 EPFDLIRLSLSERVFVKLRGDREVVGILHAYDGHMNLILSDVEETIMIVMLFVR Copci EPFDLIRLSLSERVFVKLRGDREMTGILHAYDGHMNLILSDVEETIMIVMLFVR Croqu1 EPFDLIRLSLSERVLIKLRGDREVTGTLHAYDGHMNMVLSDVTETITIVMLFVR CryneH991 EPLDLVKLALGERVLIKLRGDRIVTGVLHAYDAHMNVVISQAEESIHIVMLFVR Crypa2 EPLDLVRLLLDEVVFVKLRGDRELKGRLHAYDSHCNLVMGEVEETVYVVMLFVR Debha1 EPLDLVRYQLDELVLVKLRGAREMKGKLQGYDSHCNMILSDAVEYIYDVMVFVR Dekbr2 EPLDLIRLRLDEKIFVKLRGNREMTGKLHAYDSHCNIVLGDAKETIYYVLIFVR Dicdi EPLDLIRLSLDERIFVKMRQDRELRGKLHAYDQHLNMILSDVEETIKVVMLFVR Dmel EPLDLIRLSLDEKVYVKMRNERELRGRLHAFDQHLNMVLGDAEETVTTVMLFVR Enthi EPIDLIKLSLDDNVFIKLRGGRKLKGKLRAFDQHLNIILTNV-------VLYIR Falba EPLDLLTLALDERVRIRLRGGRELRGRLQAYDFHLNCILSDVEETVTEILIYVR Fomme1 EPFDLIRLSLNERVFVKLRGDRELNGVLHAYDGHMNLILSDVEETIMLVMLFVR Fusgr1 EPLDLVRLLLNEVVFVKLRGDRELKGKLHAYDSHCNLVLGEVEETIYTVMLFVR Galma1 EPFDLIRLSLSERVFVKLRGDRELTGILHAYDGHMNLIMSDVEETIMIVMLFVR Ganpr1 QPLDLVKLSLDEVVRVKLRGDRELKGKLHAFDQHLNMVLGDVEETVVVVMLFVR Gloin1 EPLDLVRLSLDERIYVKLRGDRELRGKLHAYDGHLNMVLSEVEETITIVMLFVR Hisca1 EPLDLVRLSLDEVVFVKLRGDRELRGRLHAYDSHCNLVLGDVEETIYIVMLFVR Klula1 TPLDLLKLNLDERVYVKLRDARELVGTLQAFDSHCNIVLSDSKETIYELMIFVR Lacbi2 EPFDLIRLSLSERVFVKLRGDRELTGILHAYDGHMNLIMSDVEETILIVMLFVR Lenti61 EPFDLIRLSLSERVFVKLRGDRELTGVLHAYDGHMNLILSDVEETIMIVMLFVR Malgl1 EPFDLIRLSLSERVLVKLRGDREMRGILHAYDGHMNLILGDVEETIYDM-LF-- Mellp23 --FDLIRLSLSERVLIKLRGDREVTGTLHAYDGHMNMVLSDVTESITIVMLFVR Mnele EPFDLIRMSLDERVYVKMKNGRELRGKLFAYDQHLNMVLGDVEETITTVMLFVR Monbr EPLDLVRLSLEEKVLVKMRGDRQLEGTLHAYDQHMNMVLSNVVETLATVMLYVR Morel2 EPLDLVRLSLDERIYVKLRGDRELRGKLHAYDGHLNMVLGDVEETITVVMLFVR Mucci2 EPLDLVRLSLDERVYVKLRGDRELRGKLNAYDGHLNMVLGNVEETITIVMLFVR Mydma EPLDLMKFSLDEKVYVKMRNDRELRGKLHAYDQHLNMVLGDVEEIITTVMLFVR Neucr2 EPMDLVRLLLDEVVCVKLRGDRELKGRLHAYDSHCNLVLGEVEETIYVVMLFVR Orpsp11 EPLDLVRLSLDECIYVKMRGDRELKGRLHAYDQHLNMVLGDVEENITVVMLFVR Pench1 EPLDLVRLSLDETVFVKLRGDRELKGRLHAYDSHCNLVLGDVEETIYVVMLFVR Phybl2 EPLDLVRLSLDERIYVKLRGDRELRGVLHAYDGHLNMVLGEVEETITIVMLFVR Picst3 EPLDLIRFQLDEFVLVKLRGAREMKGRLQGYDSHCNMVLSEAEEYIYSAMVFVR Plicr1 EPFDLIRLSLSERVFVKLRGDRELTGVLHAYDGHMNLILSDVEETIMLVMLFVR Polpo EPLDLIRLSLDERIFVKMRQDRELRGKLHAYDQHLNMILSNVEETIKVVMLFVR Pucgr2 EPFDLIRLSLSERVLIKLRGDRVLNGTLHAYDGHMNMVLSDVIETITVVMLFVR Punst1 ------------------------------------------------------ Rhior3 EPLDLVRLSLDERVYVKLRGDRELTGILHAYDGHLNMVLGEVEETITMVMLFVR Rhoto1 EPFDLIRVSLSERVFVKLRGDRELRGVLHAYDGHMNMILSEVEETIYVVMLFVR Rozal11 EPLDLIKLCLDERVYVKLRGDRELFGRLHAYDQHLNLVLGEVQEIVTVVMLYVR Sacce1 TPLDLLKLNLDERVYIKLRGARTLVGTLQAFDSHCNIVLSDAVETIYQLMVFIR Salro EPLDLIRLSLDERVTVKMRGNRVLSGQLHAYDQHLNMVLSDVVETITTSMLYVR Schco3 EPFDLIRLSLSERVFVKLRGDRQLEGVLHAYDGHMNLILSDVEETIMIVMLFVR Schpo1 EPLDLVRLSLDEIVYVKLRGDRELNGRLHAYDEHLNMVLGDAEEIVTIFMLFVR Sorma EPMDLVRLLLDEVVCVKLRGDRELKGRLHAYDSHCNLVLGEVEETIYVVMLFVR Sphar ------------------------------------MILGEVEETITSVLLFIR Spipu1 EPLDLVRLSLDERVYVKMRGDRELSGRLHAYDQHMNMVLGDVEEIITVVMLFVR Sporo1 EPFDLVRVSLSERIFVKLRGDRELRGVLHAYDGHMNMVLSDVEETVYLVMLFVR Stehi1 EPFDLIRLSLSERVFVKLRGDRELTGILHAYDGHMNLILSDVEETIMIVMLFVR Tapde11 EPLDLVRLSLDEQVYVKLRGDRELRGRLHAYDSHCNIVLGDAEETITVVMMFVR Thetr NPLDLLRLALNERVVVKMRGERELAGKLHAFDQHLNLVLSDVEETITVNMLFVR Treme1 EPLDLVKLSLGERVFIKLRGDRTLTGNLHAYDAHMNLVLSQVEENIHIVMLFIR Trire2 EPLDLVRLLLNEVVFVKLRGDRELKGKLHAYDSHCNLVLGEVEETIYAVMLFVR Umbra1 EPIDLVRLSLDERIYVKLRGDRELRGRLHAFDGHLNLVLGEVEETITIVMLFVR Ustma22 EPFDLIRLSISERVYVKLRGDRELRGTLHAYDGHMNLILGDVEETIYVVMLFVR Walse1 EPLDLVRLSLNEQIKVKLRGDRELIGVLHAYDSHMNLILGNVDEFVTVVMLYIR Zygro1 APLDLLKLNLDERVYVKLRGARELTGTLQAFDSHCNIVLSDAVESIYELMVFVR [Cluster1945.fasta_al_trimmed; alignment length = 118] Allma1 LPTETVYGLAGDAIFAAKRRPSDNPLIVHVASLTMLVMAAYWPGPLTLLFPTVAVRFPAHPVARALIPLAAPSANASGRP-SPTLASHGR--IPLVLDAGESTVLSVLRPGGVTVEQL Ashgo11 FPTETVYGLGGSSIYKAKNRPSDNPLISHVSSIAQLLVRQLWPGPLTILLPTFAVRIPADPVARALIPIAAPSANVSTRP-SPTAAEHGK--IPLILDGGESTVIDLLRPGGFTYEEI Aspfu1 FPTETVYGLGADAIYKAKQRPSDNPLIVHIDSIEMLLIERFWPGPLTILLHTFGVRMPASPLARLLIPLAAPSANASTKP-SPTAAEHGR--INLILDGGESTVVDILRPGGVGIEEL Aurde31 FPTETVYGLGADAIFSTKGRPSDNPLIVHVSSRAMLLMDAFWPGPLTLLFPTVGVRMPAHPVGRALIPLAAPSANSSGKP-SPTRAGHDR--VPLILDGGESTVLDILRPGGVTVEQI Batde5 FPTETVYGLAANAIFSAKQRPSDNPLIVHVSSIQMLLINKFWPGPLTILLPTVAVRMPSHPVALGLIPLAAPSANTSGRP-SPTLAEHSR--IPMIVDGGESTVVDILRPGGITFEQI Botbo1 LPTETVYGLGADAIFSTKGRPADNPLIVHVSSIPMLLIDAFWPGPLTLLFPTVAIRMPSHPVARALIPLAAPSANSSGKP-SPTKAAHGK--VGVVLDGGESTVVDVLRPGGVTVEDI Botci1 FPTETVYGLGADAIYKAKGRPSDNPLIIHVCDLTMLLIKRFWPGPLTVLLPTFGARMPSSPLALSLIPLAAPSANASTKP-SCTTAQHGR--IEIILDGGESTVVDVLRPGGVSIDEI Caeel LPTDTLYGISTLLLYALKQRPYEKPLGIFLPSPTAMLANCLLPGPVTLMFENVACRVPDCPIVSTICPLAQTSANVSGSSLNPTSIDHPN--IDLILDAGGSTIVDIVRSGCAEKETM Canalb1 FPTETVYGLAGSAIYKAKNRPADNPLIVHISSIEQLLISHFWPGPLTILLPTFAVRMPNHPVARALIPIAAPSANASTRP-SPTLAEHGK--IPLILDGGESTVIDLLRPGGVSLEDI Cangl FPTETVYGLGGSSIYKAKNRPSDNPLITHVSSIDQLLIEKLWPGPLTILLPTFAVRIPANSIARALIPIAAPSANASTRP-SPTLASHGR--IPLIIDGGESTVVDLLRPGGFTYEDI Capow IPTETVYGLAANAIFRAKNRPADNPLIVHVADESQLLIAAFWPGPLTLILPTVGVRMPSHPVAKAIIPLAAPSANISGRP-SPTCGAHGK--VAGIVDGGESTVIDILRPGGITKEEI Catan2 IPTETVYGLAGNAIFAAKQRPSDNPLIVHVSSLAMLLIERFWPGPLTLLFPTVAVRMPAHPVARALIPLAAPSANSSGKP-SPTLAGHGR--IPIVIDAGESTVVSILRPGGVTLEQL Cioin LPTDTLYGVACLALYEIKARNPLKPVAICVGDLYKVLLEDLLPGPVTIVTELVGIRVPDHKFIKDLTPLALTSANVSGEE-SSLRIEDPK--LDAVVDDGGSTVVQILRPGCAYENTV CocheC53 FPTETVYGLGADAIFARKGRPADNPLIVHVHSLPQLLIERFWPGPLTLILPTFGARMPRSMIALSLLPLAAPSANASTRP-SPTAAEHGK--ITRIIDGGESTVVDILRPGGVTVEQL Coere1 IPTETVYGLAANAIFETKGRPSDNPLIVHVSSMRMLVIRRFWPGALTLIMPTVAIRFPSHPVARAVIPLAAPSANASGKP-SPTLAMHSR--LPLIIDAGESTVLDILRPGGVTFEEL Conco1 MPTETVYGLAGNAIFKAKGRPNDNPLIIHISDLGMLVIKKHWPGPLTILLPTVAVRFPEHPIARAMIPLAAPSANTSGKP-SPTLADHGL--IPLIIESGESTVLDILRPGGVTLEQL Conpu1 LPTETVYGLGANAIFSVKGRPPDNPLIVHVSSSSMLLMKHFWPGPLTLLFPTVAIRMPSNPIARALIPIAAPSANSSGKP-SPTRAEHGK--IRFILDGGESTVVDVLRPGGLPVEEI Copci FPTETVYGLGAVAIFSTKGRPPDNPLIVHVSSVTMLLMRHFWPGALTLLFPTVAIRMPSHPVARALIPLAAPSANTSGKP-SPTKAEHGK--VPLIIDGGESTVVDILRPGGITVEQI Croqu1 FPTETVYGLGACAIYQTKGRPSDNPLIVHVSSLHMLLVDRFWPGPLTILVPTFAVRIPAHPIARALIPIAAPSANLSGRP-SPTQAAHGK--IELILNGGESTVVDILRLGGLSVEDI CryneH991 VPTETVYGLAASSIYKIKNRPSDNPLIIHVSSLNMLLINAFWPGPLSLLFPTNAIRMPSHPLALALIPLSAPSANSSGRP-SPTKAQHSDG-LGCIIDGGESTVVNILRPGGLGVEQI Crypa2 FPTETVYGLGADAIYAAKGRPSDNPLIVHVCDLAMLLVKRFWPGPLTILLRTFGARMPASPLARTLIPLAAPSANASTKP-SPTAASHGR--VELILDGGESTVVDVLRPGGVSLEEL Debha1 FPTETVYGLGGSAIYKAKNRPADNPLIVHVSSIDQLLIEKFWPGPLTILLPTFAVRIPQHPIARALIPLAAPSANASTRP-SPTLASHGK--IPYIIDGGESTVVDLLRPGGVSVEDV Dekbr2 FPTETVYGLGGSSIYAAKHRPADNPLISHISSIEMLLIEKFWPGPLTIVLPTFTVRMPVHPIARALIPIAAPSANASTRP-SPTQAAHGR--IPLIIDGGESTVVDLLRPGGVPMEKI Dicdi FPTETVYGLGANAIFKAKGRPLTDPVIVHIIESEYALSDNFWPGPLTIVAKYVGVRFPNHPLAQQLIPIAAPSANRFGHV-SPTTANHNKD----IDDNNESTVLKILRRGGVSEKSL Dmel LPTDTVYGLACDALYEIKGRDEHKPVAICVHNIDALLLTRLLPGPLTIVIEKIGIRIPDFNFMRDLCPLALTSANRSSAP-SSLQVSEPQ--LGAVFDAGASTVIDIVRAGVALKPTL Enthi FPTETVYGLGADVIFKVKGRPNDNPLICHISDIEMLLIKRFWPGALTIIFPTVGVRMPSHPIAYEFIPIAAPSANLSTKP-SPTIGRHGR--IEMIIDGGESTVLMILRPGGVTLEML Falba -------------------------------------MPSFWPGPLTLILPTVGVRQVAHPITQKLLPVAAPSANVSGRP-SPTCAQHGA--VP-VLEGGESTIVDLLRPGGVPVSAL Fomme1 FPTETVYGLGANAIFSTKGRPQDNPLIVHISSLPMLLVKAFWPGPLTLLFPSVAVRMPSHPVARAVVPLAAPSANVSGKP-SATRAEHGR--LRLVLDGGESTVVDVLRPGGVTVEDL Fusgr1 FPTETVYGLGADAIYSAKGRPSDNPLISHVCDLDMLLIERFWPGPLTILLPTFGVRMPSSPLALSLIPLAAPSANASTKP-SPTAAQHGR--IELILDGGESTVVDVLRPGGLGMDEL Galma1 FPTETVYGLGALAIFSTKGRPPDNPLIVHVSSFNMLLMKHFWPGALTLLFPTVAIRMPSHPVARALIPLAAPSANTSGKP-SPTRAEHGK--VSLILDGGESTVVDVLRPGGITVEDL Ganpr1 IPTETVYGLAANAIFAAKNRPADNPLIVHVSSLDMLLFRKFWPGPLTVLLPTVAFRFPSHPVARAVIPLAAPSANSSGRP-SPTTAQHGK--IPAVLDGGESTVVDVLRAGGVAWEDV Gloin1 IPTETVYGLASNAIYAVKNRPADNPLIVHVSSLKMLIIKKFWPGPLTILLPTVAVRFPSHPISRALIPLAAPSANTSGKP-SPTLASHGK--IPLIIDGGESTVFDILRPGGITFEAL Hisca1 FPTETVYGLGADAIYKAKQRPSDNPLIVHVSSKEQLLISKFWPGPLTIILPTFGVRMPSSPVARLLIPLAAPSANASTKP-SPTTAQHGR--INMILDGGESTVVDVLRPGGVGIEEI Klula1 FPTETVYGLGGSAIYKAKNRPSDNPLITHISSLSQLLVEKLWPGPLTILLSTFACRIPANPIARALIPIAAPSANASTRP-SPTTAEHGR--IPLILDGGESTVVDLLRPGGFTYENI Lacbi2 FPTETVYGLGASAIFSTKGRPPDNPLIVHVSSLTMLLIKHFWPGPLTLLFPSVAIRMPSHPVARALIPLAAPSANSSGKP-SPTRVEHGK--VPIILDGGESTVVDILRPGGITVEEI Lenti61 FPTETVYGLGALAIFSTKGRPPDNPLIVHVSSREMLLLKHFWPGPLTLLFPAVAVRMPSHPVARALIPIAAPSANSSGKP-SPTRAEHGK--LGVILDGGESTVVDVLRPGGVTVEDL Malgl1 FPTETVYGLGACAIYHAKNRPADNPLIVHVSDRRMLLMKAFWPGPLTLLFPTVGLRMPSHPIARALIPVAAPSANASGRP-SPTTAGHHV--LSYIVDGGESTVVDVLRPGGISVEQI Mellp23 FPTETVYGLGACAIYRTKGRPADNPLIVHVSSLHMLLIDEFWPGPLTFLVPTVAVRIPSHPIARALIPIAAPSANLSGRP-SPTEAEHPS--IKLVLDGGESTVIDVLRLGGLSAEDI Mnele LPTDTIYGICCAVIYQTKGRSFSKPLAICVSSVQEIILPKLLPGGVTVVLPTVGVRVPDHEFVLSLCPIALTSANISNGP-NSTSIEEDD--LDLIVDGGGSTVVEIIRRGRDYDKTI Monbr LPTDTIYGIAAVALYDIKERDPAKPIAICVPKVADVVLHQLLPGAVTVVFKLIGIRVTNHSLTQAIVPIALTSANKAGAA-SCVQADEPA--LGCVVDGGGSTVVDLLRDGDAEQHVV Morel2 MPTETVYGLASNAIFKAKNRPQDNPLIVHVSSLKMLLIRTYWPGPLTLLFPTVAVRFPSHPITRALIPLAAPSANSSGKP-SPTLASHGK--IPMVIDGGESTVVDILRPGGITFEQI Mucci2 IPTETVYGLAANAIFAAKNRPQDNPLIVHVSSIDMLVIKQHWPGPLTIILPTVAVRFPAHPVARSLIPLAAPSANSSGKP-SPTLASHSR--IPLILDGGESTVLDILRPGGLTYEAL Mydma VPTDTIYGVAALALYNIKNRQKEKAIAICVGSIEDVVLEDLLPGPVTLVFQSIGVRIPKCAFIQTLAPIALTSANISSAM-SSLDIKEPK--LDLIVDGGGSTVVDIIREGCAYNEVV Neucr2 FPTETVYGLGADAIYAAKGRPSDNPLIVHVCDLSMLLITRFWPGPLTILLPTFGCRMPASALARSLIPLAAPSANASTKP-SPTAAQHGR--IALILDGGESTVVDVLRPGGVSLEEI Orpsp11 ---------------------------------------------------------------------------------------------------------------------- Pench1 FPTETVYGLGADAIYRAKQRPSDNPLIVHVDSLDMLLIDRFWPGPLTIILPTFGVRMPSSPLARLLIPLAAPSANASTKP-SPTTAQHDR--IDMILDGGESTVVDVLRPGGIGIDEI Phybl2 IPTETVYGLAANAIYSAKNRPQDNPLIVHVSSLSMLVIKKCWPGPLTIILPTVAIRFPSHPVARALIPLAAPSANSSGKP-SPTLASHGR--IPMILDGGESTVLDILRPGGVTYETL Picst3 FPTETVYGLAGSAIYRAKNRPADNPLIVHVSSLDQLLIDKFWPGPLTILLPTFAVRMPNHPIARALIPLAAPSANASTRP-SPTLAQHGK--IPYILDGGESTVVDLLRPGGVSVEEI Plicr1 FPTETVYGLGALAIFKTKGRPADNPLIVHVSSLDMLLMERLWPGALTLLFPTVAIRMPSHPVARALIPLAAPSANSSGKP-SPTRAEHGK--LGVILDGGESTVVDVLRPGGVTVEEI Polpo ---------------------------------------------------------------------------------------------------------------------- Pucgr2 FPTETVYGLGASAIFKAKGRPSDNPLIVHVSSLNLLLIERFWPGPLTLLVPTVAVRMPAHSISRALIPIAAPSANLSGRP-SPTTAQHTK--IPMIIDGGESTVVDILRLGGLSVEDI Punst1 FPTETVYGLGALAIYSTKGRPADNPLIVHISSLSMLMIKRFWPGPLTLLFPTVAIRMPSHPVARSLIPLAAPSANSSGKP-SPTRAEHGK--VDIILDGGESTVVDVLRPGGVTVEDI Rhior3 IPTETVYGLAANAIFAAKNRPQDNPLIVHVSSIDMLVIHQYWPGPLTIILPTVAVRFPSHPIARGLIPLAAPSANSSGKP-SPTLASHGR--IPLILDGGESTVLDILRPGGLTFEAL Rhoto1 FPTETVYGLGGSAIFWAKGRPADNPLIVHISSREMLLMDRFWPGPLSLIFPSVCVRMPSHPIALSLIPLAAPSANLSTRP-SPTSAAHGRG-VGAVLDGGESTVVDVLRAGGVTAEQI Rozal11 IPTETVYGLAADAIFQVKNRPQDNPLIVHISSFEMLILEHFWPGPLTVLFERVAVRMPSHPIARSLIPLAAPSANLSGRP-SPTTAAHGR--IEYILDGGESTVLDILRPGGITLEDL Sacce1 FPTETVYGLGGSAIYRAKNRPSDNPLITHVSSIDQLLISSLWPGPLTILLPTFAVRIPANPVARALIPIAAPSANASTRP-SPTLASHDK--IPIILDGGESTVVDLLRPGGFTYEEI Salro VPTDTIYGLACLAIYSIKGRSELKPIAICVHDVAAILLRALLPGPVTVVLPLIGVRVPDFPFVRKLVPLALTSANRSGEQ-SCISSSEGE--LNAVYDAGGSTVVDVIRGGSAEEATL Schco3 FPTETVYGLGALAIFSTKGRPADNPLIVHVSSMSMLLMKHFWPGPLTMLFPTVAIRMPSHPVARALIPLAAPSANSSGKP-SPTRAEHDK--VDVILDGGESTVVDVLRPGGVTVEDL Schpo1 FPTETVYGLGADAIYKAKNRPADNPLIVHVASLDQLLIKKFWPGPLSILLPTFAVRMPQHPVALALIPLAAPSANASTRP-SPTLAKHGK--IPLILDGGESTVVNILRPGGISLEEI Sorma FPTETVYGLGADAIYAAKGRPSDNPLIVHVCDLSMLLITRFWPGPLTILLPTFGCRMPASALARSLIPLAAPSANASTKP-SPTAAQHGR--IELILDGGESTVVDVLRPGGVSLEEI Sphar VPTDTIYGLATRALYDIKGRNFFKPIAICVASVLDVLLEKLLPGPVTVILRVVGIRVPDNDFVLQLMPLALTSANMAGEE-SAVCVTDPK--ISSVVDGGGSTIVDIVRDGSALQETT Spipu1 FPTETVYGLGANAIFRAKGRPSDNPLIVHVSSLKMLAIARTWPGPLTILVPTVAVRFPSHPIARALIPLAAPSANTSGRP-SPTLASHGR--VPLILDGGESTVLDILRPGGITVEEL Sporo1 FPTETVYGLGASAIFSAKGRPSDNPLIVHVSSRQMLLMDKFWPGPLSLVFNSICIRMPRHRLALELIPLAAPSANLSSRP-SPTCARHGRG-VGAVLDGGESTVVDILRAGGVSVEDI Stehi1 FPTETVYGLGALAIFSTKGRPADNPLIVHVSSLSMLLMRRFWPGPLTLLFPTVAIRMPSHPVARALIPIAAPSANSSGKP-SPTRAEHGK--LEVILDGGESTVVDVLRPGGVTVEDM Tapde11 FPTETVYGLGANAIYAAKNRPPDNPLILHISSLKSLLIAAFWPGPLTIILPTFAVRMPSHPLALALLPLAAPSANTSTRP-SPTTAQHGL--IPIILDGGESTVVDVLRPGGLSIEQI Thetr FPTETVYGLGANAIFAAKRRPADNPLIVHVSGREMLLMTAFWPGPLTLLLPTVGVRMPSHSVARALIPLAAPSANLSGRP-SPTTAGHGR--IPWVVDGGESTVVDVLRPGAVTLEQL Treme1 FPTETVYGLGASTIYKIKNRPSDNPLIVHVSSLDMLLISSFWPGPLTLLFPTLATRMPAHPLALALIPLSAPSANSSGRP-SPTTAEHSEG-LGCILDGGESTVVNVLRPGGLGVEEI Trire2 FPTETVYGLGADAIYAAKGRPSDNPLIVHVSDLRMLLIERFWPGPLTILLPTFGARMPSSPLALSLIPLAAPSANASTKP-SPTAAQHGR--IEFILDGGESTVVDVLRPGGISMEEL Umbra1 MPTETVYGLAANAIYSVKNRPQDNPLIVHVSSLSMLLLEKLWPGALTIIVPTVAIRFPSHPVARALIPIAAPSANSSGKP-SPTLASHNR--IPLILDGGESTVLDILRPGGCTYEDI Ustma22 FPSETVYGLGANAIYAAKKRPADNPLIVHVSDLEMLLIKAFWPGALTLLFPSVAVRMPSHPIARALIPMAGPSANASGRP-SPTTAGHGR--LRYILDGGESTVIDVLRPGGVTVEQI Walse1 FPTETVYGLGANAIFKAKGRPNDNPLIVHVSSFKMFLTKHLWPGPLTILVNTVGVRMPSHPVARALIPLAAPSANSSGKP-SPTTADHAREVMDFILDGGESTVIDILRPGGVTVEAI Zygro1 FPTETVYGLGGSSIYRAKNRPSDNPLITHVSSIDQLLISKLWPGPLTILLPTFAVRIPSNPIARALIPIAAPSANASTRP-SPTMASHGR--IPLILDGGESTVVDLLRPGGFTYEQI [Cluster1950.fasta_al_trimmed; alignment length = 104] Allma1 MHSLWSRVNTVFGFATSVLLALAAAIALT-AVFVALQFDATADLRALFQ-WNTKQVYAVVTVAYQAPGNKITVWDTIITNVDDLMVVNITARLEWCVHTYVGAT Ashgo11 MFSLAQRFQVVSNKAMSWSLVTMAFVIVT-KENVRLEFDLDADLAPLFN-WNTKQVFVYLTAEYNEPDNVVTFWDHIIQDKAKVTLRALSFKLHWNIQPWVGPL Aspfu1 MHSSLSRAQGVFGFFTTVALFVAGVAALS-EEYAQIRFDLNADLSSLFN-WNTKQIFVYVYASYSSSDSESIIWDTIISSS--LRLSNVTLSVGWNVQPWVGAL Aurde31 -------------------MVLVALISIV-QDFAFFKFNYDADLAPLFD-WNTKQLFLYLVADYTNAKNEVVIWDRIVRRKEDLRIADVGFTMHYNLMPHMGLL Batde5 MHDLQSRISAIASFFLTVLATQFSLVALL-TNLGVISFDLDADLSSYFQ-WNTKLLFVSAIVEFTNSQNQAVIWDDLISDKEDIVLKNANLTLQLQVVPWVGVM Botbo1 MHSIYHRASNIASLLSTCVCALLVAVALS-QPAAQVKFDLKADLTPLFN-WNTKQVFVYLVAEYTNAQNKVVLWDRIVRRRKDIAARSATFMLEYNIMPYVGVL Botci1 MHSSVVRIQNVFGFFTTVAFVVAALIACT-EEYAHIRFSLNADFSSLFN-WNTKQVFVYVSASWPSNSNEAVIWDTIIMKKL-LKLKNVVLKVHYNVQPWVGAL Caeel MHNLLSRANALLAFTLWVMAAVTAACFLS--DLATLNFNLKVDFSKIFN-WNVKQLFVYLVAEYKSKVNQVVLWDRIVR-ADRMDEIGVTFVLRYNVIPNSGYL Canalb1 MFNLVTRAQAAANSAFTSSIVITSVVIVL-KENAKIQFDLSSDLTPLFN-WNTKQIFIYLTAEYPGKSNKVTFWDKIITNKEDLTLTNATVRLEWNIQPYVGPL Cangl MYSLSQRINQVFNVAVLYGGVIVVLVALV-KENMRIEFDLDADLSPLFN-WNTKQVFVYLTASYNGTENTVTLWDKIIKTPKELHLEHLTFELQWNIQPWVGIL Capow MHSAFQRINTLSAFSVSVLTALAIGCFLT-VDVAALTFDLHADFSSVMN-WSTHVVFIYLTAEYETQNNQVVVWDKILQ-GDNLNYKEVTLSLHWNVIPLIGSL Catan2 MHSITSRASAVASYATSALIALAAVIAAA-RHYGLVHFNLTADLAPLFT-WNVKQVHAMLTLSYGAPGNKMTIWDAILPDREDIVLANATLRLEYCVHTMLGAI Cioin MNTFLSRLNTLFAFSISVVAAVTFACFLT--DLGHIRFSLKANMTPVFN-WNCKELFLYLMAEYETPRNQVVLWDKIIR-GENLDLKKITLSLHWNVIPNAGYL CocheC53 MHSTLVRLQNAFGFFTTVAFTVATVIALS-EEYAHIKFDLDADLTSLFN-WNTKQLFVYLKAVYPSTRSEAIIWDAIIKSKLPLHLQNVVLELGWNVQPWVGAP Coere1 MYNFLQRLSALTSFAMSTLMVLAILISVT-AEYARLTFDVDADLSSMFN-WNTKLLFAYITADYRAPGNRVVVWDRIIRNPRQLRLRKANLTLHINPVPYLGLM Conco1 MHNFNIRASLVFGYLNTAVGVLLALLAAS-ADFVLGNFNLQADLTHLFH-WNTKQLFVYLVAEYENEKNYIVLWDDIIKKKERLKFKNATISLRWDTIPYVGPF Conpu1 MHSIYARINGLTALLSTCVMVLLGTIALS-REFAFVNFNVTADLTPLFN-WNTKQLFLYLEAEYENVKNDVVIWDRIVRRKEDINVQGAHYSLKYNVMPYVGVL Copci MHSIWARINNTSALLSSCMMALLAAIAVS-QDLAFVDFNITADLTPLFN-WNTKQIFLYLQAEYNTRKNEVVIWDRIVRSKDQVNVVGANYTLMYNVMPYVGVL Croqu1 MHTIIQRINGVSAFATTTLMVLMAAIAAV-REWTNLRFDLEADLRSLFT-YNTKQVFVFLVANYSTPTNEVVIWDRIIRKSKDINLSGATYTLHYNLMPKLGAL CryneH991 MYSTLQRANHISSLATTYVLILLGLISIA-EDIASLRFDVRTNLNELLNSYNTKQLFLYLTATYEEETHEVVLWDRIVRKKGRVRVEDANLTLHYSLMPYVGYL Crypa2 MYSSIVRIQNTFGFFTTVAFVIAALIAAT-EEYAVIKFSLDADLSSLFT-WNTKQVFVYVTAEWDDAASQAVIWDTIILKKL-LSLKNVQLRLHYNVQPWVGAL Debha1 MFNIVTRFQYAANQALTSSIIIAGIVIVS-KENSRIQFDLETDLSPLFN-WNTKQLFVYLTAEYPGKSNKITYWDKIITSKEDLLLKNAVVKLEWNLQPHIGPL Dekbr2 ------------------------------KENVKLRFDLEADLTSLFN-WNTKQVIIYLVGNYNNSQSNVVFWDRIIKDRDHIHLKNATMKLEFNVQPWVGPL Dicdi MHSLSQRANTIVCFGGIVLVGVLLLNVLSNFEYSFISIDLDANLEPLFN-WNTKMLFLYVTAEYRTKQSQVVVWDHIL--TEKANIHEIKLTFNYNVVPISGIL Dmel MHTVLTRGNATVAYTLSVLACLTFSCFLS--DLGFVTFDLQTNLTGIFN-WNVKQLFLYLTAEYQTPANQVVLWDKIIR-GDNLDFKNVSLYLSWNIIPNAGLL Enthi MYHTLERMYNISYFAFQWLGVAVFFLYLS-T------IDLDVDFTPSFN-WNTKMIFVWVKASFTNKNNTATVWDTMIRKKEKLHLTNVELTVEWMVVPWSGAT Falba MNFTSKRFFSLTTHLVSSLVFAVFVLFLC-KDVAVVRFDLDIDFTGVFQWWNTHMVFVYLVAEFETDANHVTIWDDRV-SRDALTLTNGRLALHWNVVPVLGSF Fomme1 MHSIYQRFSNISALLSTCMLALFGAISIS-HEFSFVRFNVSADLTPLFN-WNTKQLFLYIGAEFTSADNEVVIWDRIVRRKEDINVSSANYTLKYNVMPYIGLL Fusgr1 MYNSLTRIQNTFGFFTTVAFVVAAFIAAS-EEYAIIRFNLDADLRSLFT-WNTKQVFIYVTAEWPGP-NEAVIWDKIIMKKL-LGLKNVKLKLHYNVQPWVGFL Galma1 MHSIFSRVNNGSAFLSSCMMALLAAIALS-QDLAFVHFNITADLTPLFH-WNTKQLFLYLEAEYINKQNEVVIWDRIVKRKEDIKFAGANYSLKYNIMPYVGAL Ganpr1 MYSISQRANAVLAFLVTVTLGFLVAVALT-SELAIIRFDISADLRDLWN-WNTKQLFVYVVAEYETDSNQVVIWDSIIRNKDDIRLRNAKFTLHWNIIPYVGAL Gloin1 MYNLAQRANAIFAFAMTVHFGLLLAIAIS-TEFAFIEMNIDADLTSLFN-WNTKQLFVAVVAEYETKSNQVVLWDSIIQSKEDIKEDKANYSIYWDLMPYVGYL Hisca1 MHSALNRLQGVFGFCSTLAFLLGALTSLT-EEYAQIKFDLDADLTSLFN-WNTKQVFVYVLASYPTAPTESIIWDMIIKSK--LRLRNAQLVVAWNVQPWIGAL Klula1 MFSLNQRFQHVSSLALSCSFLVIALIAAT-TEVSKIRFNADFDFSRLFN-WNTKQVFAYVTAEYEGDENEITIWDKIIPSRDNFTLSDLTFKLHWNIQPWFGFL Lacbi2 MHSIFSRINNVSALLSSCTMALLAAIALS-QDLAFVNFNITADLTPLFH-WNTKQLFLYLEAEYINAQNDVVIWDRIVRRKEDINVAGANYSLKYNVMPYVGYL Lenti61 -------------MGSTCLMVLLGAIALS-QDFTFVNFNLTADLAPLFN-WNTKQLFLYVSAEYENKQNEVVIWDRIVRRKEDLNIAGAHYSLKYNVMPYVGVL Malgl1 ------------------------------QHFVETRLNLDFDTQPLFN-WNTKQVFLSLTASYDSPRQDVVVWDKIVRNDDEIRISYLDFRIEWNVMPFVGLM Mellp23 MHNIMGRLNSVSAFATTVVMFLMVAISGV-REWTNLRFGVEADLRPLFN-YNTKQIFVYLVATYATPTNEVVLWDRIIRKSQDINLSGATYTLHYNVMPKMGAL Mnele MNNLTSRANVILANSLSVLAICTGMLFIS-LDLALLRYDLKIDMSDSFH-WNVKMIFLYLVAEYTNEKNQVVLWDKIVR-GDNVDLKNTTLSLHWNVVPNAGLL Monbr MHNFVTRANALFAYAFSCLAIATLGCFLT-YDRASFTFDIDADLSPLFN-WNTKQLFLYMTAEYKTRKNQVVVWDQIVRNSGAFNLSNVTLALHWNVIPVAGLL Morel2 MNSLQNRANAVMAFSISAIFCLLGAIAFS-NEFANTVMRIDADLSSLFH-WNTKQLFVYAVAEYSTPTNQIVLWDTIIKRKSAISKRGANVTLHWNIVPYVGFM Mucci2 MYNLQQRANNVFSFAITVIGTVLAVVAVI-SEFARLTFDIDADFTPLFN-WNTKQVFVTVVAQYENEKNQVVLWDKIITSQDKLKLRNASLTLLWDVTPYVGVL Mydma MHTVLSRLNVVFAYCLSVLGAITVGCFLS--DMGFLKFNLKSDLEPLFN-WNVKQLFLYLTAEYKTKSNQVVLWDKIIR-GENLDLQDITLTLSWNLIPNAGIL Neucr2 MYTSVVRLQNVFGFFTTVAFVVAAFIAAS-EEYAVINFSLDADLSSLFT-WNTKQVFVYVTAEWPAADNEAVIWDTIIMKKL-LSLKNVTLRLHYNVQPWVGLL Orpsp11 MFSFYNRGSTFLNFLCTVLPVLLALLACT-GDIALIDFDINADLTSVFN-WNVKELFVYLVYEFQTPKNQVVIWDDIITSKQNIKGKN---------------- Pench1 MHSSLNRIQSVFGFFTTVALVVSALAAVS-EEYAQLRFDLDADLSPLFN-WNTKQLFVYVYATYSSSDSESIIWDTIIVSSDALRLRGVTLHVGWNVQPWVGAL Phybl2 MYDLQQRANAVLSFAVTAFACFLGVVSLL-SEFARLAFDIDADFTPLFN-WNTKQIFVTVVAEYESASNAVVLWDRIISRKDDLLLENANLSLQWDITPHVGIL Picst3 MFNLVTRGQAVANQALTSSVFIIVTIVAI-KENAKIQFDLDADLTSLFN-WNTKQVFVYVTAEYPGKSNRVTFWDKIIVSKEDLHLVNAVVRLEWNIQPHIGPL Plicr1 MHSIYSRFNNTSAYMSSCLMALLGLIALS-QEFAFVNFNVSADLTPLFH-WNTKQLFLYLGAEYTNAQNEVVIWDRIVRRKEDVNVEGAHYSLKYNVMPYVGLL Polpo MHSVSQRANLIVCFGGVVLFGVLLLNVLSPVELAQVHMSLQADLTPLFN-WNTKQLFLYITAEYQTKESQVVLWDYIL--KDKAVLKEVTLTFNYNVIPISGLI Pucgr2 MHTIAQRINAVSAVATTTIIFLVAGIALI-REWTNFRFAVEADLRPIFR-YNTKQIFVYLVADYSTPENEVVLWDRIIRNPRDINLSGATYTLHYNLMPKVGAL Punst1 MHSVYARINNVSTYLSSCLLALLGAIALS-QEFTFVNFNVTADLTPLFH-WNTKQLFIYVQAEYTSAKNEIVIWDRIVRRKEDVNVAGAHYSLKYNLMPYVGAL Rhior3 -------------------------------------------------------------------------------------------------------- Rhoto1 MYSLAQRLSNISALATTVLLTLLTAISAT-REFAFVKFDLKADLSPLFN-WNTKQVFVYLTADYATPENTVVVWDRIVRSSRHIDVQDATFSLQYQVQPYVGVL Rozal11 ------------------------------------------------------MIYAYL--------NEIIFWDKIIRTDEK-----ATVSFRYNTIPWVGLL Sacce1 MFSFVQRFQNVSNQAFSMGIVMVVFIMAS-KENMKIKFDLNTDLTPLFN-WNTKQVFVYLTAEYNSTESEVTFWDKIIKSKDDIDVNDLVFKLHWNVQPWVGLL Salro MHSALTRGNAIFSLGFTCVALATFLCAVT-FDRAYFTFDLNAGTCMPVT-AN-------VVASCTTVRNQIIVWDKIMRDIDDISLRDITLSLHWNVVPVAGLL Schco3 MHNILTRINNLSALLSSCLMGLVAVIALS-QDVTFTKFNITADLSPLFH-WNTKQVFAYLQAEYTNAQNEVVIWDKIIRSKDELNLVDATYTLKYNIMPYVGLL Schpo1 VDTFTNRGSTFFSKLSTVLFFLCAVITFQ-QQYAQVKFNMDADLSELWD-WNTKHVVVYLVASYSTEKNQVVVWDKILSSPEEMFMKDATYTLHWTVSPKMGFL Sorma MYTSVVRLQNVFGFFTTVAFVVAAFIAAS-EEYAVINFSLDADLSSLFT-WNTKQVFVYVTAEWPAADNEAVIWDSIIHWSR-LVLKNVTLRLHYNVQPWVGLL Sphar ---------------------MSAASWAS-SENAIFKIDLEVDVTECFN-WNVKE------------------------------------------------- Spipu1 MHTLSQRANTLFAFFVTVLFSVLGAVAIS-TELGLIQFNLDADLTTLWN-WNTKQLFLYVVAEYETPSNQIVIWDDIITSKEDVTLRNTNLSLHWNIVPHVGLL Sporo1 -------------------------------------------------------------------------------------------------------- Stehi1 MHSVYARFNNISATLSTCMMVLLGAIACT-QEFAFVNFNVTADLTPLFN-WNTKQLFLYLGAEYTNAQNEVVIWDRIVRRKEDVNVEGAHYTLKYNVMPWVGVL Tapde11 MWSSSQRAQTVFGLFTSVLFALAAAIALT-QEFAHVQYDLTADLSSLFH-WNTKQVFAYLVAEYPGTKNEVTLWDVIIRKKQDLSLNKATFSLHWNVMPHVGVL Thetr LHNVAHRMNVVLTTAFMFLLVLVAANWLSRRDVANVSLAISMDLTPLFH-WNTKMVFVYAYAEWPSKNNQIVLWDAIAS-ADDLEFPALNLTVVYNRIPHTGPL Treme1 MHSTFQRLNNITSLATTYLMVLLSLISIA-EELASIRFDLTTDLTTLLTSYNTKQLFLYLTASYETDPHEVVLWDRIIGKKGRIRVEEANLTLHYSLMPYVGLI Trire2 MHSSFTRLQNVFGFFTTVAFVLGAFIAAT-EEYAIIRFSLEADLSSLFT-WNTKQLFVYVTADWTGP-NSAVIWDSIIMKKL-LKLKNVTLRLHYNVQPWVGLL Umbra1 MHNLQQRLSATFSFAVSALFTVLGVVAAI-SEFGMLKFDIDADLTPLFN-WNTKQVFVTVVAEYETKTNQVVVWDKIIRDKDSINLRKANLSVHWDVTPHVGIL Ustma22 MHSTLSRLNAVSALATTIILVLVVLIDVT-QDFVQVDFNIDADFAPLFD-WNTKQVFVSLSASYDSAKSEVVIWDRILRSKQDVALNTTTFTLKYNIMPKVGLL Walse1 MFTTLARLNSLSAIISSSLFVLIGMISLT-NEFAFLRFDGLIDSSHLFDNWNTKQVFVQLTANYNNKNSSTVVWDKIIKPHQQTRIENATLTLTYDIQPYVGLN Zygro1 MFSLSQRFQTLGNQAITYGLFISVFIAIT-KENAKITFDLETDLTPLFT-WNTKQVFAYLTAEYDGKNNEVVFWDKIITSKDELKVNGLEFKLKWNIQPYVGPL [Cluster1956.fasta_al_trimmed; alignment length = 121] Allma1 -----------------------------------------MLHTLLTALVK-ADVYWKSIGEWADVLVAWAKDNGFANTVVTGYEVRL-GDYVFYAMDEAVFAKVVA-HLDHQRRGFKII Ashgo11 SELPSIYNFPPLYTQPNSLIRGRRVWIMGHNVQLQRRVPGPFVDEIWAHALA-KGVLWRSLDSWSALLLQWFETCGRLNQVVTIYELVA-GDESFHGMHDGLCELALG-KLVERGRAVKVI Aspfu1 FQFPPTYSFPPFFTQPNSTTRHHRIYRLSLNATLRKRLSLSEARAVLDWMAK-PEIWWRRPEEWAGIVADWVEATGQKNVVLTVYELLE-GEATWHGMDADVMLKSLN-ILVKRGKGVKFF Aurde31 FTLPSIHSLHPFFTQPNPTTRHTRLFTLRVNPEIGRTLQASYLESILGTMVA-QGLLWRSVDEWAETLFEWASNTGQLNTIMTYYEIQE-PEL-LSGIPTPLLRRAIA-ALIKSGRGVRLF Batde5 FEYPSVYSFPPFFTQPTLDTQHTRTFIIDVNPKIQRSLSRESLVLILDHLVSVMKIYWRTPEEWASQVYTWVFNTGRTGTVCTTYEVFC-GDETFHGIPEEIIKKVLD-VLAKQGKGIKFI Botbo1 YVLPSIHAWPPFFYQPGAATRHHRLFHLHPNPRIKRSLKAPYLSSLLASLVA-QGLYWRLPSEWAEILFDWASSTAQLNTILTFYEITN-PPV-LVDLPLPLLRSAIA-ILAKSGRGVRFF Botci1 FKFPREHSFPPFFTQPTSSTAFHRLFRLTVNERINRRLDEEGLREVLEFMRK-EGVWWRKVDEWARVIEDWVDETGQRGSVLTLYELVE-GEGGFHGLDTEILQKALA-ILVKRGKGVKFF Caeel FKWPWQYDFPPFFTQKSLNTQHNKIYSLDINQKLNRRLSTDGVNTVLQYLEQ-KKIFWRRPDVWANMIYQWAVENAFINTPLTLYEITH-GDDTFHNLEREILMKALT-CLEEQRRGVKFI Canalb1 FEFPKIYSFPPFYTQPNTTVEYYRITSLSINKTINRQVNSDFQKLIVKHLIH-N-IYWRSLVDWGDLLYQYVDDTGQKGTVLTIYELTKSEETTLHNLDETFLVKIIKDYLIKQGKGVKIV Cangl --MPSIYAFPPLYTQPNSLVKSHRVFELGKNEEINRAVPPLFIDEIWSVMAT-RGVLWRTLDSWASLILQWFETVGKLNQVVTLYELTE-SDETFHSMPLPLLHRCLK-PLCNRNRALKVV Capow FAWPALYSFPPFFTLAGATERRHAADSLDVNQTINRHLSPEAVRIVLDELAA-KGVLWRTIEQWAAIIYSWVENNGMTGTVCTLYELQA-GDHAMYGIDENTLKEALA-VLQAQRKGVKFF Catan2 LHLPPIYSFPPFFTQPHLPSAHHKLYRLDLNAGINRSVSREMAAAIFRECVK-SGVLWKSVAEWGNVLCEWAKRNGFTGSVVTGYEMRF-GEYVFAEMDEQLFIRVVK-DLTKQGKGFKFL Cioin FRWPWQYDFPPFFTQKNADTNHHKLFRLRVNKAIDRRLTKPDVIEILSILHK-KGVFWKTPAQWSDIIFKWVNQSGLNNTVCTLHEITN-GPHSFYALDDQILMQAIQ-ILQASGKGVKFF CocheC53 FTFPPHYSFPPFFTQPVASTRHHRIFTLSLNATLGRSLSLRDAKAILTYMAS-AEVYWRRPEEWATAIEEWVERTGQKGTVLTLYEIVE-GDAVFGGMDMDLLQKSLG-VCVKRGKGVKFF Coere1 FEFPEIHNFPPFFTQPNEDTKHNRLSLMPLNRQIHRSLQVDTLREIIEELVR-QGVYWRKPEVWANIIHMWACEHSLCNTVLTLYELAN-GDDTFHGLDLSTLRRSLE-ILQSQGKGIKFF Conco1 FNYPSIYSFPPFFTQTNISTKFNKEFELVLNKSINRSLKPEIVREIIDLLVG-QGILGKSIEEWGIIIYQWVSDTGSLNSVLTQYELTQ-GDLVFYQLHPTILKWSLE-DLATKGKGVKFF Conpu1 FLLPSIHSAPPFFTQPNPRTRHRKLFMLRVNERINRRILPSHLSSLLDTMVA-SEIYWRTPEEWADALHAWAVATGQLNTILTFYEIAD-PPV-LSGIPIPLLRRAVT-FLVKSNRGVRLF Copci ------------------------------------------------------------------------------------------------------------------------- Croqu1 YKFPSIYSFPPFFTQPNPQTRFHRLFKFELNASISRS------------------VYFHPLSYWSSLIYNHVLSHGLTNSVMTLHELSS-DEAGLEGLDGFVLRKALG-VLVKQGKGVKFF CryneH991 FEYPTIWSFPPFFTQPNPQTRHERVFEMNTNRTINRRLLPNSLKILMGEMVK-NGIYWRKPEEWGDIIYHWVMDNGLNSSIMTFYEITD-GDLSFHELPISILRKALE-TLVKRGRGVRFL Crypa2 FTFPREYYFPAFYTQTNLNTRHYRIFKLPLNRRLNRRLALSDIREVIDFMRR-DGIYWRTPEEWAALVEGWVDETGQKGTVLTLYELTQ-GDATFHGLDQDLLQKALN-VLVKRGKGVKFF Debha1 FEFPKIHSFPPLYTQPNLTIQHYKITSLTLNKNINRAVNDDFKAMIFKHLIH-KLIYWKTLIEWANILHDFVERTGQLGSVLTIYELTKLEDSGLKDLDYNLLVRILKGVLIKQGRGVKIV Dekbr2 FSFPKLYNFPPFFTQPNQQTRFYRIWALSLNTKINREVKGDFIMTIYESLIE-KKIYWNSLEDWATMLMNWVVSTGQDGNVLTIYELQN-GEAVFAGMATETLTRVIS-VLAKEGRGVKFG Dicdi FQFPPYYHKEPFFTQPILNTRYYKIYELDINEKINRKLSREALKSIIDDIIE-NGIMWRKPDEWASLIYKWVADCGLLNTVLTVWEIQN-GDDSFHQLNTTILMKSLK-VLEKQSKGVKFF Dmel FQWPWEYTFPPFFTQPHEETRHTNRFTLSINEALKRRLSPELVLAILGELER-SGVYWFTLEEYGNMVYDWVQETGQTNTICTLYEIAS-GENTFYGVDEAVLLSALR-LLEEKGRGVKFF Enthi FGIPEFAKFPPFYTQLVDKTKQSEFNKLP-NEELHRTLSENGIELVKEFMVN-NNLLYKPLREWGKELYEYGNSKGLIGQSDTFFSIENDKESVFYQMDDELLIEGLN-SIKEQGKGIFWL Falba ADFPAIYNFPPFFTQPNQDT----------NSNIGRKISPELGRAILDHMLE-RGILHRSAFEWADLIERYAAEVGLRDTVLTLEEFLL-GRETFHGMDRTFFKTVVAPELGRRNRGLKFV Fomme1 FLLPSIHSFPPFFTQKNVTTRHRNLFFLKVNERINRRVLPDFLAFLLETLVV-KNLYWRTPEEWGEVLHEWATSTGQLNTILTFYEITD-PPV-LSGIPDVMIRRAIA-SLGRTARGVRFF Fusgr1 FKFPREYHFPAFFTQTNLTTRHNRIFRLSLNRKLDRRLQFDDIRDVVSFMHT-DGLYWRKPEEWAELVENYVEESGQKGSVLTVYELVE-GDGTRLNLDMS-------------GR-MSY- Galma1 FLLPSVHSWPPFFTQPNPTTRHRKLFILRVNERLNRIILQNHLSNIIASMVD-KNVYWRLPEEWAEVLYDWVIAMGQLNTILTFYDITD-PPV-LTNIPTPLLRKAIA-ILAKTGRGVRFL Ganpr1 FTFPPMHDFPPFFTQPNPESEDKQNLYIE-NEKIKRSVSPQLLNAIFDELAR-QGIWYRTPDEWAVKMHEWCRATSKVGQVCTLGDFKE-SEAF-----------PLD-SFAALRCAVKFM Gloin1 FSFPSIHNFPPFYTQPTQTTRHHKLYRLNLSQGIRRKLKLDTLQAIIDTMVY-RGIYWRKPEDWANLINNWVLETGMSNSIVTVYEIAH-GDSAFHGLDQTILMKALD-ILVKKGVGVKFF Hisca1 FKFPATYSFPPFFTQPNTTTRHHRLYRLSLNADIHKRLSLADARTVVDWMVR-GEIWWRTPEEWASVLADWVEETAQKNTVLTLYELME-GEATFHGMDPDVLSKSLN-VLVKRGKGVKFF Klula1 LETPQIYKFPPLYTQTNKLIAQLSKWCINKNPEIQRACSLEFQQEIWAYMLQ-NEIFWESLDSWSSTILEWCETSGKLNQVITIYEICE-SDENFYGMPSSFCLLVLH-RLVDRNRGVKIV Lacbi2 FLLPSIHSAPPFFTQPNPATRHRKLFVLRVNEPINRKVLPSHLSSILEAMVA-KNLYWRLPEEWADVLHEWATSTGQLNTILTFYDITD-PPV-LSNIPVPLLRKAIA-ILVKSGRGVRFF Lenti61 FVLPSIHAAKPFFTQPNSATRHRKLFTLRVNPRIQRRLRPSHLAAILSSMVA-ANLFWRSPEEWAQVLYDWANSTGHLNTIMTFYEIVE-PPV-LEGLPLPILRKAIS-VLTKSARGVRFL Malgl1 FAFPGVHEFAPFYTQPNPETAAHHRFQLEVHRGLDRALSPDTVRLIFAYMVE-KGVYWNTPTEWGDQLYEWVKQTGQNRSVLTLYELQQ-STFV---LPPAMLMRALE-TLVARKCGVKFV Mellp23 -----------FFSQPNPQTKFHRLFKIELNASISRK------------------IYFYPITYWSNLIYDYIVSNGLTNSIMTLYELTS-DEVILRGLDEYVLRKALG-LLVKQGKGVKFF Mnele VSSTSLYDLTVFFISKNPETRSSNLFRGEINKKIGRQLSPAAIRVVLQSLCD-EGVLWNSVAQWASLIHNWAVDRGLTNTVLTLFEIHG-GDDTFHTMDIWLLHHVIS-YLEKEGKGVKFF Monbr EEAPWEYSFPPFFTQPNEETKRANINRLVVNRAIARSLNADGIRSVLDYLEQ-RGLIWQSPARWAQLLYDWAVRTGNTDTVCTFYELRE-GESTFHGIDAEMLRKAVA-ALQREHKGIKFF Morel2 FQFPSIHNFPPFYTQPTASTRHHRLYQLDLNQRISRALKPETIQAIVEEMVK-KGIFWRKPEDWAAMISSWVFESGLNNSILTFYEIAH-GENSFYNIHPTVLQKTMD-VLVKRGVGVKFF Mucci2 FQYPPMFDFPPFFTQVTESTRQKHIFRLDLNKKINRRLSFETLQDIIEEMAR-KGIYWHTPEDWANLIWNWINETGQNNQIVTYYEIAH-GELAFFELDKAILSKALN-ILVKRGNGVKFF Mydma FEWPWQYNFPPFFTQPNLDTKYYKLYRLDLNASINRKLSRDGILLVLEALEK-TGLMWRRPEEWSELVYNWVNMNGMTDTVCTLFELHS-GDDTFHNIDINVLRKALQ-ILEKRGKGVKFF Neucr2 FPFPREFFFPPFFTQTNLTTRHHRLFRLSLNPRINRRLAPGDIRRVVDFLRR-DGIYWRTPEEWGSLIEGWVEETGQRGSVLTVYELRE-GEGTIWGMDGDVLVKALG-TVVKRGKGVKFF Orpsp11 FQFPAIYDFPPFYTQPNFTTRKKKITSLSVNKKIHRQLDEEKIRIILDELVK-RGILWRKYDEWANLIYKWVFDNGLTNSVCTYYELLN-GDMSFQGLDEDTLQKALE-ILVKQRKGVKFF Pench1 FPFPPTYNFPPFFTQPNTTTRHHRQYRLSLNTALRKRLDLREARAVVDWMTK-SEIWWRRPEEWADVLVDWVEGTGQKGSVLTVYELIH-GEGAFHGMDTDVMLRSLN-VLVKRGRGVKFF Phybl2 FEFPLMHGFPPFYTQPTEATRHHRIFKLDLNTKIKRRLSFETLQEIIQAMTV-QGIFWRRPEEWATLIWEWVNTNGLNNTVVTLYEITE-GDLSFYGIDSQVLIMAIK-VLVKRGDGVKFF Picst3 FTFPKIHSFPPLYTQPNATIEYFRITSMTLNNAINRSVSADFQSAIFSHLIH-KVVYWRSITEWAQLLYDFVDKTGQLGTVLTLYELTKAEDSGLRNLDEELLVKVLKDVLIKQGRGVKIV Plicr1 FLLPSIHSAPPFFTQPNAGTRHRRLFDLRINERINRRLLPSHLSHLLSEMVN-KNLYWRLPEEWAEVLHDWAASTGQLNTILTFYEIME-PPL-LTGIPISLLRKAIA-ILSRTGRGVRLF Polpo FPFPSYYNREPFFTQPILNTRYHKIYELDINEKIKRKLSQETIVAIFNEIVD-SGVWWRKPDEWASIIYQWVVDSGQTDSILTVWEIQK-GDDTFHEINTNILMKALK-SLEKQGKGVKFF Pucgr2 FKFPSIFSFPPFFTQPNQQTRYHRVFKLDVNPSISRRLNADAIFSVFEIMVQ-SGIHYDSPTTWADRIYDYISSNGLTNSVMTLHELTS-PDHQLVGLDPIILRKALT-ILVKGGKGVKFF Punst1 YILPSIHSAPPFYTQSTAQLRHRRLFTLRINPRINRRVQPQYLAYILSELVK-RKLYWRLPEEWAEVLHEWATNSGQLNTILTYQEITE-PPV-LSNVPLQVLRQAIG-ILSKNGRGVRFF Rhior3 -----------MYVQVTESTRHKHLFRLELNKKINRRLSFEALQDIIEEMVK-KGLYWHTPEEWANLIWNWINETGQNDQIVTYYEIAH-GELAFYDIDHNVLDKALN-VL-----GVKFF Rhoto1 FLFPSIWSFQPFFTQPNPQTRFTRTWRIDLNAAIKRQVPLPFLRLIIESLVS-AGIYWKRPEEWAQVIYEWVKETGQTNTIITFYELTEGGDLVFYRLPIPILRKTLD-ILIKQGKGVKFV Rozal11 ---------------------------------MNRSLS-----------------------ELSLMIFNWVDSNGLRNSVFTVYELCH-GNLTFHGVPTKSMKRALK-ILERQ--GVKFS Sacce1 SALPPVYSFPPLYTQPNSLTKTKKIWYMSVNEDIQRSVSQVFIDEIWSQMTK-EGILWKSLDSWASLILQWFEDSGKLNQVITLYELSE-GDETFHRMPESLLYYCLK-PLCDRNRAIKVV Salro FNASQLKSLLATCTSPMRRRQAKRLNHLVVNKQLNRALSTDAIVTVLDFMQQ-SGVFWQSPKQWGGIIYKWAVDTGNTDTVCTFFELLE-GETGFHNMDRHVFKRALQ-QLQKEGKGVKFF Schco3 FLLPSIHSFPPFYTQPNPSSRHRRLFTLRVNERINRRLPPSHLERILASMVS-RNIYWRTPEEWAEELHQWVASTGQLGTIMTFYEIME-PPV-LSGIPLPLLKKAIS-ILAKSGRGVRFF Schpo1 MRVPSIYNFPPFFTQLNDNTRENRQTSITINSTIHRTLPLSVFREIVEDMVK-QNVYWRSISEWGNMILKWLSDMGREGSICTFYELQE-----VDCLDEVLLHKVLE-LLMKKGNGFKVL Sorma YPFPREFFFPPFFTQTNLTTRHHRLFKVSLNPRINRRLAVGDIKSVVDFLKK-DGVYWRTPEEWGSLIEGWVEETGQRGSVLTVYELRE-GEGTIWGMDGDVLVKALG-TVVKRGKGVKFF Sphar FEWPDMYNFPPFFTQRTEKTKHTIAYELTINAEINRRASDELIQKIISTLEK-SGIYWRSIAAWANTIYSWIEKTSRTDMVLTFYELRE-GDESFHGMDLVTFQKALE-DLEKVGKGVKFY Spipu1 YTFPSIHDFPPFYTQPTAATAATRTFSIDLNERLRRSLNREGIQTIIDALVN-QGVLWRKPEEWASLIYKWAFDTGSTNSICTVYELIH-GEGTFHDLDERTMIKALE-ALSKTGKGVKFF Sporo1 YHFPSLYSFPPFFTQPNPATKHTKTSYFPPNRQIQRSLPLDVVQEVLRHMSTAMNVYWKTPFEWTETIYDWVKATGQLGTVLTLYELTE---------------------------G---- Stehi1 FVLPSIHSAPPFFTQPNETTRYRKLFVLRVNERINRRLLPSHLSFIIASMVT-KNLHWRLPEEWAEVLHEWASASGHLNTILTFYEITD-PPV-LSGLPTPLLRKAIA-ILSKSGRGVRFF Tapde11 FELPPIHSFPPFFTQPNVETRHNKLFQLSLNRSIKRSLKLDTLMEIIEHMVA-QNIYWRRPEDWAQALIKYVEDTGQNGSILTMYELTE-AEEAFYKMDKVMLRKVVD-VLSKRGKGIKFL Thetr YEFPRFYSFPPFFTQPNEETAAHNVSQLEINAAIDRKLSEDALRLFIDDLVA-TRIMPATPDEVAAAIYDWIDTTGQIGDVLTVYELHS-GDTTFHGLDAVLINRALD-VLASQGKGVKFF Treme1 FIFPPIWNFPPFFTQPNLSTRFRKVFMINVNKDIDRRLQTTSLKTLMIHMTE-RNLYWRKPDEWGGIIYDWIIENGMNNTILTWYELTD-GDLAFYQLPLPMLRRALD-TLVRKGKGVRFL Trire2 FAFPREYSFPPFFTQPNIAIRHHRLFRLVVNRAINRRLGPADIREVLDFMRK-DGLYWRKPEEWAALVEAYVDETAQKGSVLTVYELTE-GENTFHGMDNLVLMKALN-ILVKQGKGVKFF Umbra1 YKFPAIHDFPPLYTQPTESTRSQRLYRLNLNTKIKRRLSLETLEEIVNEMVR-KGIYWRKPEEWSSLLWNWINEQGFNNSIMTVYEIAN-GEAAFYEMDTTVLIKALE-VLSANGNGVKFF Ustma22 FRYPPIHAFPPFFTQHNPVSRHHRLFTISPNQSIQRSLSAESIRVVLTHLVD-HKIYWKTPVQWADSIYDWVMQTGQNKSIMTLFELNQ-GDLVFYLLPTPMLRQALK-HLSTQGKGVKFV Walse1 --MTTIIDFPPFYTQPNVETKQRRQFQLSMNEKIQRTRVILLSTVICYYLLISTGVYWRTLAEWAAVLYDHVDGTAQLNTPLTYYELTE-GDYSLNGLPTPILRSAIN-ILVKQNKGVKFI Zygro1 MPLPPIYSFPPLYTQPNSIIKSHNAWCMSANNEIERSVPQVFINEIWSTMCQ-EGILWRTVDSWASLILQWFESAGKLQQVVTIYELSQ-GDESFHGMPEPLTADCLK-PLCHRHRAVKVV [Cluster1960.fasta_al_trimmed; alignment length = 166] Allma1 QFRRVLIPPHRLTPLKKEWLQIYTPLVEHMGLQVRFNVELRS-LQKGHDFVKAFAVGFDVTDALALLRLDDLFLDSFEIKDVK-TLNGDHLSRAIGRIAGKNGKTKFTIENASRTRIVVADTKIHILGSFQNIRVAKDAVVSLILGSPPGKVYSTLRTVSARMKER Ashgo11 ESRKVPVPPHRMTPLRNSWTKIYPPLVDHLKLQVRMNVELRT-LQKGADFIKAFTLGFDLDDSISLLRLDDLYIETFEIKDVK-TLHGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRLKER Aspfu1 ETRKVPVPPHRMTPLKANWPKIYPPLVEHLKLQVRMNVELRT-LQKGEDFVKAFTLGFDVDDAIALLRLDDLYIRSFEIRDVKASLNGEHLSRAIGRIAGKDGKTKFAIENASRTRVVLQGTKVTILGRFRDLGIAQEAIVSLILGSPPGKVYGNLRKVASRMKER Aurde31 ETRRIPIPPHRMTPLKKDWIHIFTPLTEMAGLQVRMNVEIRT-LQRGADFVKAYALGFDVNDAVALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENASRTRIVLADTKIHILGTFQNIKIARDAIVSLILGSPPGKVYANLRTIGARLKQR Batde5 DARKIPIPPHRMTPLRKDWLKIYTPLVEHMKLQVRMNVEIRS-VQKGADFVKAYGLGFEVDDALALLRLEDLYVDTFEIKDVK-TLHGENLSRAIGRIVGKDGKTRFTIENVSRTRIVVADCKIHILGSFQNIKIARDAIVSLILGSSPGKVYSQLRSISSRMKER Botbo1 EIRRIPMPPHRMTPLKNDWVNIFTPLTEILGLQVRMNVEVQT-IQKGADFVKAYALGFDVNDAIALLRMDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKYTIENASRTRIVLADTKIHILGSFQNIKIARDAIVSLILGSPPGKVYASLRTIGSRLRQR Botci1 ETRKVPIPPHRMTPLKAAWPKIYPPLVEHLKLQVRMNVELRT-LQKGEDFVKAFSLGFDVDDAIALLRLDDLYIQTFEIKDVK-TLQGEHLGRAIGRIAGKDGKTKFAIENASRTRVVLADSKIHILGGFKNIHIAREAIVSLILGSPPGKVYGNLRTVASRMKER Caeel ESRVVPVPKHRYTPLKDNWVNIFTPIVKNLGLQVRFNVEIRN-LQKATDFVRAFILGFEVNDAIALIRLDHLFLETFEVADVKHSLKGDHVSRAIGRIAGKDGRTKLVIENTTKTRIVVANTKIHILGAYQNLKLARNAVCSLILGSNPSKVYGSLRNMASRGAER Canalb1 ESRKVAVPPHRMTPLKNVWSKIYPPLVEHLKLQVRMNVELRT-LQKGADFVKAFTLGFDVDDAIALLRLDDLYIETFEIKDVK-TLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRMKER Cangl ESRKVPVPPHRMTPLRNSWNKIYPPLVDHLKLQVRMNVELRT-LQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVK-TLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRLKER Capow GFRKVLVPAHRYTPLRENWLKIYTPLVQHMKLQIRMNVELKT-LQRGADFVRAFMLGFDIADAIALLRLDNLYIDTFEVLD------------------GSGGKTKFTIENVTKTRIVVADSKIHILGSFQNIKVSRDAIVSLILGSPPGKVYGQLRSVAGRMASR Catan2 QLRRVLIPPHRQTPLKKEWLKIYTPLVEQMGLQVRYNVEIR------------------VDDAMALLRLDDLYIDSFEIKDVK-TLNGDHLSRAIGRIAGKSGKTKYTIENASRTRVVVADTKIHILGSFQNIRVAKDAIVALIMGSPPGKVAATLRTVSSRMKEG Cioin SLRKVPVPANRYTPLKENWMKIFTPVVENLRLQIRFNVEIQT-LQRAADFVKAFVLGFSVEDALALVRLDELFLESFQVTDVK-RLKGDHLSRAIGRVAGSGGRTKFTIENVTKTRIVLADTHIHILGSYQNIRLARTAICNLILGSPPSKVYGNMRAVASRSAER CocheC53 EQRKVPIPPHRMTPLKNSWPKIYPPLVEHLKLQVRMNVELRT-LQKGEDFVKAFTLGFDTDDAIALLRLDDLYIETFEIKDVK-SLSGEHLSRAIGRIAGKDGKTKFAIENASRTRIVLADQKIHILGGFKNIHIARESIVSLILGQNPSKMYGNLRTIAGRMKER Coere1 EFRRIRVPPHRLTPLKRDWLKIYSPIVEHLKLQVRVNVEIRT-IQKAADFVRAYCLGFSAEDSLALLRMDDLFLDSFEVKDVK-TLTGDHLARAIGRLAGKDGKTKYTIENATKTRIVLADSKIHVLGTFQNIKIAKNAISSLIMGSPPGKIYANLKIVASRMKGR Conco1 ESRKIPIPPHRLAPLKKGWMSIYSPLVEHLKLEVRMNVEIRT-LQKGADFVKAIALGFDIPDAVALLRLDELYLDSFEIKDVK-TLHGDHLARAIGRIAGKDGKTKFTIENTTKTRIVLADTKIHILGSFQNIRLAKDAVCSLILGSPPGKVYATLRSVAARMKER Conpu1 ETRRIPIPPHRMTPIKKEWVNIFSPLTEMLGLQVRMNVEIRT-LQKGADFVKAFALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLQGDHLARAIGRIAGQDGKTKFTIENASRTRIVLADTKIHIMGSFQNIKIARDAIVSLILGSPPGKVYAGLRTVASRMKQR Copci ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 QTAKVPIPPHRMTPLKASWPQIYTPLVEELGLLVRVNIELKTTMTKAVNFLQCFNLGFAVEDAVALLRLEEIYIESFEIKDVK-SLTGDHLSRAIGRIAGKDGRTRFTIENTSRTRIVLADTKIHILGSFAAIRIARDAICALILGSPPGKVYHGLRTVAARQRER CryneH991 EFRRIPIPPHRMTPLKRDWVNLYTPMVEMLGLQVRMNVELKT-IQKGADFVKAYALGFDVNDALALLRLDDLYLDSFEIKDVK-TLHGDHLARAIGRIAGEGGKVKFSIENASRTRIVLADTHIHILGSVQNIKIARDAVVSLILGSPPGKVYAHLKAVGARMKQR Crypa2 EQRKVPIPPHRMTPLKAAWPKIYPPLVEHLKLQCRMNVELRT-IQKGADFVRAFALGFDVDDAIALLRLDDLYIETFEIKDVK-TLQGDHLARAIGRIAGKDGKTKYAIENASRTRIVLADSKIHILGGFKNTRIARESVVSLILGKPPGKVYNGLRTVSARMKER Debha1 ESRKVPVPPHRMTPLKNTWTKIYPPLVDHLKLQVRMNIEMKT-LQKGADFVKAFTLGFDVDDAIALLRLDDLYIETFEVKDVK-TLNGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRMKER Dekbr2 ESRKVAIPPHRMSPLKNNWIKIYPALVKQLKLQVRMNVELRT-LQKGADFIHAFALGFDLDDAIALLRLDDLYIETFEIQDVK-SLHGDHLSRAIGRIAGKDGRTKFAIENATRTRIVLADSKVHISGGFSHIKMAREAVMSLILGSPPGKVYGNLRTMASRLKER Dicdi QIRKVTIPFNRIAPLKANWQQIYEPIVTHLKLQIRMNVELKT-LQKAADFVHAFSLGFEVNDAVAILRLDDLYIDSFDVEDVK-ILKGDNLSRAIGRVAGKDGKTKFTIENVTKTRIVLADKRIHILGSYSNIRVAKDAICDLIIGSPPGKVYAKLRTVSSRIAER Dmel ELRKVSVPPHRYSSLKEHWMKIFTPVVEHMKLQIRFNVELRV-LQRGADFVRAFLCGFEVDDALALLRLEDLFVESFEIKDVK-TLRGDHQSRAIGRLAGKGGRTKFTIENVTKTRIVLADSKIHILGSYQNIQLARRAVCNLILGSPPSKVYGNLRAVASRLSER Enthi ELREIHVPGQRFNYVKENWIGIYQPIVSQLKLNIRMNIQLKT-LQKASDFINAIGKGFEVKDAIALLRMDDIFVDSFEIEDVK-KLHGDHLNRAIGRIAGKDGKTKFSIENTTHTRIVMQYKKIHIMGSYANIKIARDAIQDLILGAPPGKVYNNLRTIASRMDSA Falba ESRKIPVPGHRFTPLKDNWMKIYTPLVEHMMLQVRMNVEIRT-IQKGADFLRAFMLGFDVEDAMALLRMDDLYIDSFEMKDVK-TLNGDHLGRAVGRVAGHGGRTKFTIENTTRTRIVLAETHIHILGTFQNIAVARDAIVSLILGSPPGKVYNHLRAVSTRLQER Fomme1 EMRRIPIPPHRMTPLKNEWVNIFGPLTEVLGLQVRMNVEIRT-IQKGADFVKAFALGFDVNDSIALLRMDDLYLDSFEIKDVK-TLHGDHLARAIGRIAGHSGKTKFTIENASRTRVILADTKIHILGAFQNIKIARDAIVSLILGSPPGKVYAGLRTVASRMRQR Fusgr1 ETRKIPIPPHRMTPLKQSWTSIYPPLVEHLKLQCRMNVELRS-LQKGEDFVKAFTLGFDVDDAIALLRLDDLYIQSFEIKDVR-TMHGDSQARAIGRIAGKDGKTKFAIENASRTRIVLADSKIHILGGFKNIHLARESVVSLILGKPPGKVYGNLRTVAARMKER Galma1 ETRRIPVPPHRMTPLKKDWLNIFGPLTEILGLQVRMNVEIRT-LQKGADFIKAYALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENTSRTRIVLADTKIHIMGSFQNIKIARDALVSLILGSPPGKVYAGLRTVSSRMKQR Ganpr1 DFRRIPIPPHRLSPLKENWLKIYSPLVEHMKLQVRMNVEIKS-VQKGADFVKAFALGFDVEDALALLRLDDLYLDTFSLLDIR-TLSGDNLSRAIGRVAGKSGRTRYAIENATRTRIVVADTRVSILGSWANIKVARDAICELVLGAAPGKVYSKLRLLSARLKER Gloin1 NLRKISVPSHRFKPLKKDWKKIYEPLVKHLSLQVRMNVELRT-LQKAADFVKAFMMGFDVEDAIAILRVDDLYIDSFDIKDVK-KLEGDHLSRAIGRIAGKNGKVKFAIENASKTRIVLADSSIHILGSFQNIKIARDSVVSLILGSPPGKVHANLKIINARMKQR Hisca1 ETRKVPVPPHRMTPLKATWPKIYPPLVEHLKLQVRMNVELRT-LQKGEDFVKAFTLGFDVDDAIALLRLDDLYIETFEIKDVK-TLGGEHLGRAIGRIAGKDGKTKFAIENASRTRVVLADQKIHILGGFRNIHVAREAIVSLILGSPPGKVYGNLRTVAARMKER Klula1 ESRKVSVPPHRMTPLKNNWSKIYPPLVDHLKLQVRMNVELRT-LQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEIKDVK-TLQGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKER Lacbi2 ETRRIPIPPHRMTPLKKDWVNIFGPLTEILGLQVRMNVEART-LQKGADFVKAYALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENTSRTRIVLADTKIHIMGSFQNIKVARDAIVSLILGSPPGKVYAGLRTVSSRMKQR Lenti61 EIRRIPIPPHRMTPLKKDWVNIFSPLTEMLQLQVRMNVEIRT-IQKGADFVKAYALGFDVNDSIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENASRTRIVLADTKIHILGSFQNIKIARDAIVSLILGSPPGKVYAGLRTVSARMRQR Malgl1 QVRKVPIPPHRMSPLKRDWPKIYTPLVEQAGLMVRMNVEIKS-IQKACDFVKAYALGFDADDALALLRLDDLYVDSFEMKDVK-TLHGDHLSRAIGRIAGKDGRTRFAIENASRTRIVLADTKIHILGAYQNIRMAKDSIVALIMGSPPGKVYAKLRTVSARMRQR Mellp23 QTAKVPIPPHRMTPLKASWPQIYTPLVEELGLLVRVNIELKTTMTKAMNFLQCFNLGFAVEDAVALLRIEEIYIESFEIKDVK-ALTGDHLSRAIGRIAGKDGRTRFTIENTSRTRIVLADTKIHILGSFASIRIARDAICALILGSPPGKVYHGLRTVAARQRER Mnele EMRKVPIPPHRYTPLKENWMKLYTPIVEQLKLQVRFNVELKT-IQKAADFVKAFTLGFDIDDCLALVRLDDLFLETFEIADVK-TLKGDHLARAIGRIAGKGGRTKYTIENVTKTRIVLADSKIHILGSFQNMRIARTAICNLILGSPPAKVYGKMRTVASRMSER Monbr QFRRIPVPPHRYTPLKENWMGLYQPVVEHMKLQIRMNVELKT-LQKAADFLKAFMLGFEVQDAIALLRMDELYIDSFEIKDVK-PLSGEHLSRAIGRIAGKGGKTKYTIENTTKTRIVLADDKVHILGAYQNIRMARDAIANLILGSPPGKVYGKMQVVASRMSER Morel2 QQRKIPIPPHRMTPLKNEWMKIYSPLVDHLKLQVRMNVEIRT-LQKGADFIKAFALGFDLDDATALLRLDDLYLDSFEIKDVK-TLNGDHLSRAIGRIAGKDGKTKFTIENASKTRIVLAETRIHILGSFQNIKTARDAIVSLILGSPPGKVYSTLRTKAARMKER Mucci2 GSRKIPIPPHRMSPLKRHWLEIYSPLVEHMKLQVRMNVELKT-LQKGADFLRAFALGFEVEDAMALLRLDDIFLDTFEIKDVK-TLHGDHLARAIGRIAGRDGKTKFTIENASKTRIVLADTKIHILGSFQNIKIARDAVVSLILGSPPGKVYATLRTISARMKER Mydma EFRKVAVPPHRYTPLKENWMKIFTPVVEHLHLQIRFNVEIRT-LQKAEDFVKAFMLGFDVNDALALLRLDDLFLESFEINDVK-TLKGDHLSRAIGRVAGKGGKTKFTIENVTKTRIVLADSKIHILGSFQNIKIARTAICNLILGSPPSKVYGNMRAVAARSVEK Neucr2 ETRKIGIPPNRMSALKANWTKIYPPLVEHCKLQVRMNVELRS-LQMGADFVSAFAMGFDIDDAIALLRLDSLYIQSFDVKDVRQTLGPDALGRAIGRIAGKDGKTKFAIENATKTRIVLAGSRVHILGAFENIGMARESVVSLILGHQPGKVYNNLRIIASRQKER Orpsp11 -------------------------------------------------------------DAIALLRLDDLYIDTFEIKDVK-TLHGDHLSRAIGRIAGKNGKTKFAIENASRTRIVVADTKIHVLGSFQNIRIAKNAISSLIMGSPPGKVYSHLRNVSSRVRER Pench1 ETRKVPVPPHRMTPLKASWAKICPPIVEHLKLQVRMNVELRT-LQKGADFVKAFTLGFDLDDAIALLRLDDLYIQTFEIKDVK-TLNGEHLGRAIGRIAGKDGKTKFAIENASRTRVVLADQKIHILGGFKNIHIAREAIVSLILGSPPGKVYGNLRTVASRMKER Phybl2 GQRRIPIPHHRLSPLKRQWLEIYSPLVEHMKLQVRMNVELRT-LQKGAEFVKAYALGFEIEDAMALLRLDDIFLDTFEIKDVK-TLHGDHLARAIGRIAGKDGKTKFTIENASKTRIVLADTKIHVLGSFQNIKIARDAVVSLILGSPPGKVYATLRTISARMKER Picst3 ESRKVAVPPHRMTPLKNVWPKIYPPLVDHLKLQVRMNVELKT-LQKGADFIKAFTLGFDVDDAIALLRLDDLYIETFEIKDVK-TLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRMKER Plicr1 ETRRIAMPPHRMTPLKKDWVNIFGPLTEMLGLQVRMNVEVRT-LQKGADFVKAYALGFDVNDAIALLRLDDLYLDSFEIKDVK-SLHGDHLSRAIGRIAGQDGKTKFTIENASRTRIVLADTKIHIMGSFQNIKVARDAIVSLILGSPPGKVYAGLRTVSSRMRQR Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 QTAKVTISPQRLTPLKKSWPQIYTPLVEELGLMVRMNVELKSTITKAVNFLQCFNLGFAVEDALALLRLEEIYIESFEIKDVK-TLTGDHLSRAIGRIAGKDGRTRFTIENASRTRIVLADT-------------------------------------------- Punst1 ETRRIAIPPHRMTPLKREWINIFGPLTEMLGLQVRMNVEVRT-LQKGADFVKAFALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENTTRTRIILADTKIHILGSFQNIKIARDAIVSLILGSPPGKVYAGLRTVSARMRQR Rhior3 GQRKIPIPPHRMSPLKRHWLDLYSPLVEHMKLQVRMNVELRT-LQKGADFVRAFALGFEVEDAMALLRLDDIYLDTFEIKDVK-TLHGDHLSRAIGRIAGRDGKTKFTIENASKTRIVLADTKIHILGSFQNIKIARDAVVSLILGSPPGKVYATLRTISARMKER Rhoto1 QRRKISIPPHRMTPLKRDWIKIYTPLVEECGLQVRMNIEMKT-LTRAADFLSAYCLGFAVEDAIAMLRMEELYIESFEIKDIK-MLHGDHLSRAIGRLAGHEGKARFAIENATRTRIVLADTRIHILGTFSNIAVARSSISALVLGSPPGKVFANLSRYASLQRSR Rozal11 EYRKIPVPHNRITPLRQNWLKIYEPLVDYMKLQVRMNVELRT-LQKGADFVRAFTLGFDVDDAIALLRLDELYIDSFEIRDVK-SLTGDHMSRAIGRVAGKSGKTKFAIENATRTRIVVADSKIHILGSYQNTILAKRAIVSLILGSPPGKVYGNLKNVATRMKQS Sacce1 ESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNVELRT-LQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVK-TLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKER Salro ETRSIDVPPHRYTPLKENWNKIFQPVVEHMKLQIRMNVELRT-LQKAHDFVKAFMLGFDVADAVALLRLDDLYLDTFDVTDVR-RVAGDHLSRAIGRVAGKGGKTKFTIENATKTRIVVADSRVHILGAFDNIREARHIISKLIIGSPPSKIYATLQSVTQRLSGR Schco3 ESRRIPIPPHRMSPLKREWINIFGPMTELLGLQVRMNVEMRT-IQKGADFVKAFALGFDVQDAIALLRMDDLYLDSFEIKDVK-TLQGDHLSRAIGRIAGQDGKTKFTIENASRTRIVLADTKIHILGSFANIKVAKDAIVSLILGSPPGKVYANLRTVSARMKQR Schpo1 QMRRVPIPPHRMTPLRNVWPKLYPPLVEHLLLQVRMNVELRE-LQKGMDFVQAFALGFDIDDAIALLRLDDLYIDTFEIKDVK-TLQGDHLSRAIGRIAGQGGKTKFAIENASRTRIVLADSKIHILGGFTNIRIAKDAVVSLILGSPPGKVYANLRNAAARAKER Sorma ETRKIGIPPNRMSALKANWTKIYPPLVEHCKLQVRMNVELRS-LQMGADFVSAFAMGFDIDDAIALLRLDSLYIQSFDVKDVRQTLGPDALGRAIGRIAGKDGKTKFAIENATKTRIVLAGSRVHILGAFENIGMARESVVSLILGHQPGKVYNNLRIIASRQKER Sphar SERRVQVPTHRMTPLKQQWLKIYTPLVEHMKLQVRMNVELKT-LQRGADFLKAFMLGFDVDDALALLRLDDLFIDTFDVNDVK-MLKGDHLSRAIGRIAGKGGRTKFTIENVTRTRVVIADSKIHILGSFRNIRVARNAICQLILGSPPGKVYGNMRSVASRMSER Spipu1 EFRKIPVPPHRLTPLQKEWIKIYSPLVEHMKLQVRMNVELRT-LQKGADFVKAFCLGFEINDAIALLRLDDLYIDTFEIKDVK-TLAGDNLSRAIGRIVGKDGKTRFAIENTSRTRVVIADTKIHILGSFANIRVARDAIVSLILGSTPGKVYSQLRTISARMKER Sporo1 QRRKVGIPPHRMTPLKRDWIKIYTPLVEECGLQVRMNIEMKT-LTRAVDFLSAYALGFAVDDAIAMLRLEELYIETFEVKDVK-TLHGDHLSRAIGRIAGHEGKTRFVIENASRTRIVLADSKIHILGTFSNIKVARDAISALILGSPPGKVYANLRTYASRQRSR Stehi1 ETRRVPIPPHRMSPLKKDWVNIFGPLTEILGLQVRMNVEIRT-LQKGADFVKAYALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGQDGKTKFTIENASRTRIILADTKIHILGSFQNIKIARDAIVSLILGSPPGKVYAGLRTVSSRMRQR Tapde11 SSQKVPIPPHRMSPLTAAWPKIYPPLVEHLKLQVRMNVELRT-LQKGADFVKAFSLGFDTDDAIALLRLDDLYIDTFEIKDVK-TLQGDHLSRAIGRIAGKDGKTKFAIENATRTRVVLADSKIHILGGFQNIKVARDAVVSLILGSPPGKVYSNLRNVSARMKER Thetr EVRRLPVPPHRYTPLKQNWEHIVDPIVNVLGLAIQMNIEIQN-LQRAADFVKAFLLGFDLDDAMALLRLDDLYVDSFEIDDVK-RLQGNHRSRAIGRICGAQGKTKHTIENALRVRIVVADSKIHILGAFTNIKLARRAVCSLIMGTPPGKVYGQLRSASARLATR Treme1 EFRRVAIPPHRLSPLKRDWVNIYTPLVEMLGLQVRMNVELKT-VQKGADFVKAYALGFDVNDAIALLRLDDLYLDSFEIKDVK-TLHGDHLSRAIGRIAGEGGKVKFTIENASRTRIVLADTNIHILGSVQNIKIARDAVVSLILGSPPGKVYAHLKTVGARMKQR Trire2 ETRKIPIPPHRMTPLKQAWPSIYPPIVEHLKLQCRMNVELRT-LQKGEDFVKAFTLGFDVDDAIALLRLDDLYIETFEIKDVK-TVHGDSQSRAIGRIAGHQGKTKFAIENASRTRIVLADSKIHILGGFKNIHMARESVVSLILGKPPGKVYGNLRTVAARMKER Umbra1 QARKIPIPPHRLSPLKKSWLQIYSPLVEHLKLQVRYNVEIRM-LQKGADFVRAFALGFEVEDAIALLRLDDLYIDTFEIKDVK-TLHGDHLSRAIGRIAGKDGKTKFTIENASKTRIVLADTKIHILGSFQNIRIARDALVSLVLGSPPGKVYATLRTISARMKER Ustma22 QLRKIAIPPHRLTPLKNEWHKIYTPLVEMASLQVRMNVELKS-LQKGADFVKAFALGFEADDAIALLRMDDLFIDTFEIKDVK-TLQGDNLSRAIGRIAGKDGRTRFAIENASRTRLVIADTKIHILGNFANIKIARDAVVALIRGSPPGKVYANLKTIGARQRQR Walse1 QTRRVLIPGHRMSPLKKDWVNIYGPLVEMLKLQVRMNVELRS-LQKGADFVKAYALGFAVEDAIALMRLDDLYIDSFEIKDVK-TLHGDHLSRAIGRIAGQNGKTKFALENATRTRIVLADTHIHILGAFNNCKLCKDSICSLILGSPPGKVYNHLKVVGARLKQR Zygro1 ESRKVGVPPHRMTPLRNNWTKIYPPLVEHLKLQVRMNVELRS-LQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVK-TLNGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADAKIHILGGFTHIRMAREAVVSLILGSPPGKVYGNLRTVASRLKER [Cluster1961.fasta_al_trimmed; alignment length = 133] Allma1 KAKTDRTGLVYMSRVPRFMPPDVVRKLLSIGRIYLALEDNGRKNYVEGWIEFLDKREAKAVAKALNNELIGGRWHDSIWNLKYLPKFKWHHLTEQIRQREQRLRNEIMQAKRYLENVAKGKMV-SAK-K-AKR Ashgo11 KKSNHKTGVVYLSKIPPYMKPAKMRQILSLDRLFLKREDNKKVMFREGWAEFIRKKDAKLCAETLNGNIIGGKYHDDVMNVKYLSGFKWADLTEQIDVRQSKLQLEISQANKFIRNVEKSKML-NAK-K-HK- Aspfu1 PPKKNKTGVIYLSSLPPYLKPFALKSMLEITKVFLTPEVNKRKSYADGWVEFASKKTAKICAETLNATIVGGKYHDDVWNMKYLKGFKWADLMEQVSEREAKRRIEDTRARKFLQGVEQGKVL-QKK-N-EEK Aurde31 QAAQERAGIIYLSRIPPGMRPTKVRHLMSVGRVYLQQEDTKKAHYTEGWVEFADKKVARSVAAMLNAQPIGGKWRDDVWTMKYLPRFKWNMLTEQIAVHRERLRIELSQSKTYLHNVELARVL-KEK-R-KAK Batde5 QDKINRTGVVYLSRIPPFMKATKMRSLLAIGRIFLNPEDNKRQNFKEGWIEFLDKDQAKRTAATLNNTIIGGKFYDDIWNIKYLPRFKWNHLTEQLKVKEQRVQTEMAQAKRYLKNVSKAKMI-QAK-K-S-- Botbo1 RQAQERAGIIYISRIPPGMRPPKVRHLMSVGRVYLKQEDTRKVHFTEGWVEFLSKKVARSVADMLNARPIGGKWRDDVWTMKYLPKFKWNMLTEQVATRTARLRVELSQSKSYLRNVELAKVL-EEK-K-RKR Botci1 AAAIKRSGVVYLSRIPPFMKPTKLRSLLEINRIFMTPEDNKKRSFVDGWVEFVNKADAKKVCELLNANTIGGKYHDDVWNLLYLKGFKWNNLTEQIAERSSRMRAEISKTTKYVQNVERAKIQ-EAK-K-AAK Caeel ------------------------------------------------------------------------------------------------------------------------------------- Canalb1 QKRIKRTGVCYLSRVPPYMKPAKLRSVLSIDRLFLKPEDNKKKNFTEGWIEFVNKSDAKLCAATLNGNKLGGKYYDDIINIKYLPGFKWLDLTQQIEVRQAKLAMEISQQQKFVSNVEKSKMI-AKK-R-KTT Cangl QKLKHKTGVVYLSRIPPYMKPAKMRQILSIDRLFLKREDNKKIMYEEGWAEFIRKRDAKLCAETLNGNIIGGKYHDDILNVKYLPGFKWADLTEQIDVRQAKLELEISQSNKYIRNVEQSKML-QKR-K-DH- Capow NEKVAKSGVLYLSRVPPHMKPDKIRHLLQIGRVFLQPEDNKKKNFSEGWIEFADKGVAKSVAASLNGTMIGGKYHDDLWLLKYLPKFKWHHLTEQIAVRDQRLRTELAQSKRFMENVDKSKKI-RSR-KFAKK Catan2 KAKRDRTGLVYLSRVPPFMPHEVVRKLLSLGRMYLAPEDNGRKMYTEGWVEVLDKREAKAMASNLNNQIVGGKWHDCIWNIKYLPKFKWHHLTEQIRQREQRLRAEIMQAKRYLENVAKSKMI-TDKNK-QKR Cioin LKKGPIPGVIYISFLPPKMTPLHVRQIFEVGRIFLQPEAYNKGTFTEGWIEMGDKTIAKRLAMTLNNTLISDGFSDHTWNVKYLHRFSWRHLTERLELRKQRMRVEQSLARKFISNVEASKKM-EER-K-EKK CocheC53 PLKKDKSGVIYLSRVPPFMKPAVLRSLLQVGRIFLTPESTRRKLFLDGWVEFLHKRDAKFVAENLNAQTMGGKWHDEVWNIRYLSGVKWHNLVEQIAERAARLRFEIAQGKKFLENVERGKVA-SRK-R-GED Coere1 QKRERKSGVVYMSRVPPYMRPIKVRHMLEIGRIYLIEEDNRRRQFVEGWIEFKNKKYAKAVAHMLNNTKMGGKYHEDLWNLKYLPKFKWRHLVEQLAAREQRLQTETSQARRYMKNVDRAKKM-SAK-R-QRR Conco1 NQKVAKSGVVYLSRIPPRLKPSKLRTLLEIGRIYLAPEDGNDRRFTEGWVEFEDKKKAKAYASFLNTTPMNPKHHEDLWNLKYLPKFKWHHLTERMASRNQLLTFEIQQGRKYTDKVELANRI-QKK-K-REQ Conpu1 NAAQNRAGVVYLSRIPPGMQPPKVRHLMSVGRIYLQQEDTKKPHFTEGWVEFKDKRVARSVAEMLNAQPIGGKWRDDVWTMKYLPKFKWNMLTEQIAVHAAKLRVELAQSKAYLKNVELARVL-DER-R-RQA Copci KAAQERAGVIYISRIPPGMRPAKVRHLMSVGRVYLQQEDTKKPHFTEGWVEFKDKKVARSVAEMLNAQPIGGKWRDDIWTMKYLPKFKWNMLTEQVAVHTAKLRVELSQSRAYLRNVETARVL-EEK-K-REK Croqu1 GRKVDKTGLIYLARIPNGMGPGKVKHLLSVNRIYLARHEHQSYQFKEGWIEFEDKKVARRIAELLNTRPIGGKYSSELWSLKYLPKFKWSNLSDQMRMREQLQRNSLEDSKKYLQMVEKNRIG-NEK-E-MIR CryneH991 KKKSPTPGIVFISRVPPGMTPQKIRHLMGIGKVYAQRRDHASANFTEAWVEFLDKSVAKTVASMLNAQVIGGKWRDDVWTMKYLSGFKWEMLGEQIQAHQARLRNEITRAKTYLKNVELARTL-EA-----KK Crypa2 DAAIKKSGVVYLSRIPPFMKPAKLRSLLEINRVFLTPQDNKKKMYTEGWVEFVRKKDAKSVCELLNAQTIGGKYRDDIWTLLYLKGFKWHNLTEQIAERSNRMMAEVNRTTKFVRNVEKAKML-DAK-K-AQK Debha1 QKKIKKTGVCYLSKIPPYMKPAKLRSVLSIDRLFLKPEDNKKKNYTAGWVEFINKKDAKLCAGTLNGNKLGGKYYDDIINIKYLSAFKWFDLTQQIEIRQAKLSMELSQQQKFINNVEKSKMI-NNK-R-KAR Dekbr2 QKRIKRSGVVYLSSMPPYMKPTKLRQIMEVGRIFLKPEDNKKRKFDEGWCEFKSKKAAKLAAETLNGNIIGGKYHDDILNVKYLRGFKWGDLTRALEVRESKMEAELARERRFIENVETSKKF-NRQ-RSKKR Dicdi KEQNENKGIIYLSTIPSRMKPAKLKQLLAVTRMHLVRAN--NDMFKEGWIEFEDKALARKIATILNNIPMGGKHKDCLWNLRYLPKFKWHHLQDKLMERDKKLRLEINQVRKLLEQVELSKHV-NSKGK---- Dmel PAKKRKMGIIYISNIPKHMNVTRLREILGIGRVYLQPEKRYNIHFTEGWVEFKSKRVAKQIVPLLNNKQISGRFYDSLWSMKYLPRFKWVHLTERMAVHKQRLHTEVSQARKFQNNLDKSEFI--RK-Q-AKK Enthi EENEEPHGIIYLSVIHKGLNPGIIKGIFSVSRMHFLEDK-KKGTFKEAWIEFETEKQAKLVALMLNGKVIGGKFADKIWNIRFIKGLTWGRIFEDKISQEQQIEFAMRKVKKYLANSKKVRNSKFRKER-KAK Falba KADLEKTGVVYLSRIPPFMRPHALKSLLSIGRIFLKPEDNRRINYSEGWVEFLDKSRARFAADLLNNNQIGGNFYADIWNIKYLPKFKWHHLTEQLAARERQLQAEMSQAKRYLKNVDRARAK-EQA-A-ASK Fomme1 RAAQGRAGVIYISRIPPGMRPTKVRHLMSVGRVYLQQEDTKKANFTEGWVEFADKRVARSVAEMLNAQPIGGKWRDDVWTMKYLPKFKWNMLTEQIAIRTARLRVELEQSRRYLRQVELARVL-DKR-K-REA Fusgr1 EAAIKKSGVVYLSRIPPFMKPAKLRSLLEINRIFLAPEDNKKRSYTEGWVEFTKKKDAKAVCDLLNARTIGGKYHDDLWNLLYLKGFKWHNLTEQIAERSSRMRAEISKSTKFVRNVEKAKML-DVK-A-KAK Galma1 KAAQDRAGVIYISRIPPGMRPAKVRHLMNVGRVYLQQEDTKKVHYTEGWVEFKDKKVARSVAEMLNAQPIGGKWRDDIWTMKYLPKFKWYMLTEQVAVHTAKLRVELSQSKTYLKNVELARVL-DAK-K-REQ Ganpr1 SKTRDATGVIYLSRVPPFMKPEKLRHLLAIGRVYLAREPSKKKNYTEGWVEFLSKKDAKKVAALLNNVPIGGKYHDDIWNIRYLSGFKWTDLAAQVAAREQRMRQEAAQAARYRKNVDKARMV-EEK-K-RAK Gloin1 KKAQDNTGIIYLSSIPPFMKPSKVKHLLGIGRVYLAPEDNKKKKYTEGWIEFLDKRIAKTVANTLNARPIGGNYHDDLWNIKYLPKFKWTNLTDQIATRIQRLQAEISQARRYLKKVEKAKMI-KEK-K-EKK Hisca1 APKSKKRGVIYFSSLPPYLKPRALKNLLQITRIFLTPLMNKRKTYSDGWVEFASKKTAKICAETLNARTIGGRYRDDLLNVKYLHKFGWDDLMEQVSEREAKRRIEDAQARKYLENVEAGRAV-QRK-R-EEK Klula1 KKTKHKTGVVYLSRVPPYMKPAKLRQILTVDRLFLKREENKKTMFEEGWAEFIRKKDAKLCASTLNGNIIGGKYHDDVMNVKYLPGFKWADLTEQIDIRQAKLQLEISQANKFIHNVEKSKMV-NQS-K-KR- Lacbi2 KAAQDRAGVIYISRIPPGMQPAKVRHLMSTGRVYLQQEDTKKPHYTEGWVEFKDKKIARSVAEMLNAQPIGGKWRDDIWTMKYLPKFKWNMLTEQVAIHSAKLRVELSQSRSYMKNVELARVL-DAK-K-REK Lenti61 KAAQEKAGVIYISRIPPGMRPTKVRHLMGVGRVYLQQEDTKKAHYTEGWIEFKDKRVARSVAEMLNAQPIGGKWRDDVWTMKYLPKFKWNMLTEQIAVHTAQLRVELSQSRKYLKNVELARVL-DER-K-RKT Malgl1 KKKQQKRGVIYLSRLPPGMTPAKVRHIFSVGRIYLQPKDNRPSHFSEGWIEFVSKRVARTTAEMLNAQPIGALWKDDVWTMKYLKGFRWPMLMEQLATHAARLRMELSQSAHYLRKVERSRIQ---R-K-KQA Mellp23 TQKVNKTGLIYLARIPVGMGPGKVKHLLSVNRIYLARHEHQSYQFKEGWIEFEDKRVARRVAELLNTRPIGGKYSSELWSLKYLPKFKWSNLSDQMRLREQLQRNSLEDSKKYLRMVEKNRVG-NEK-E-ISR Mnele KKTGPKPGIIYLSSIPPYMKPNKVRNIMSVGKIYLQPEDSGKKKFTEGWIEFKKKRIAKAVVQSLNGNIIGGKYHDDIWAMKYLPRFKWSNLTEKLAVRKKKLQQEMTQVKKFLEQVDKNKQI-SRK-R-EEK Monbr NAGQKKRGLIYLSRVPPFMKPAKLRHLMQVDRVFLQPEDNKKINYGERWIEFLDKSIAKRVAASLNGTKVGGKHHDDLWCMKYLPGFKWHNLTERIAARERRLAMAMSQVQRYLDQVVKAKSI-EKYGK---- Morel2 QAARDKTGIVYLSKIPPFMKPVKLRHLLGLGRVYLAPEDNKKQNFTEGWVEFKDKAIAKQVAKSLNATIIGGSYHDDMWNIKYLPKFKWDHLTERIASRAQRLQAEINQAKRILTNIEKAKMI-KEK-K-AAK Mucci2 EKARQRTGVCYLSRIPPFMRPKKVRSLLSIGRIYLVPEDNKRANFVEGWVEFKDKKRAKALAEYLNTRPMGGKYHDELWSIKYLHKFKWHNLTEHMQARKQRLRAEIAQSNRYIQNVERAKML-EQK-K-RKR Mydma KEKKVSPGIVYLSKIPPSMNPLKIRSLLLIGRVYLQAEDTSRKQFTEGWVEFLDKKVAKSVAQSLNCTNIGGKYHDDIWNIKYLPKFKWGHISEKLAAREQRMRAEISQAKKYLENVSKGKTI-S----VEKK Neucr2 EEAIKKSGVVYISRVPPFMTPAKLRSLLELNRIFLAPEDNKKKMFTEGWIEFVKKKDAKKACELLNARPIGGKYRDDIWNLLYLKGFKWHNLTEQIAERSSRMRAEISKTTKFVRNVERAKVL-QAK-K-ASK Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------- Pench1 APKKTRPGVIYFSSLPPYLKPFALKGMLEITKIFLAPLLNKRKLYTEGWIEFESKKTAKICAETLNATIVGGLYHDDVWNIKYLSRYSWEDLMQSVSERESKRKIADAREAKFIAGVESGRIA-DKK-N-EEK Phybl2 EKEQKKMGVCYLPRIPPFMKPMRVKALLSIGRIYLQPEDNRRVNYVEGWVEFKDKKRAKTLSTYLNMKQIGGKYYHDVWNIKYLPKFKWTHLTEQI------------------------------------- Picst3 QKRIKRTGVCYLSRIPPYMKPATLRSILSIDRLFLKPEDNKKKNFTEGWVEFVNKKDAKMCASTLNANKLGGRYYDDVINMKYLSGFKWFDLTQQIEVRQAKLSLELSQQQKFVNNVEKSKLV-SRK-R-KER Plicr1 KAAQDRAGVIYISRIPPGMRPTKVRHLMSIGRVYLQQEDTKKAHFTEGWVEFKDKRIARSVADMLNAQPIGGKWRDDVWTMKYLPKFKWNMLTEQVAIHQARLRVELSQSKTYLKNVELARVL-GER-K-KEA Polpo EQENQEKGIIYLSTIPEKMTPSKLKNLLLVTRMKLIKAN--NDMYKEGWIEFSEKKIARKIALLLHNQPMGGKHKDCLWNIIYLPKFKWHHLMDKLLERDKKIQLELNRVRKFMEQVEKSKII-AKKNK---- Pucgr2 GQKVDRTGLVYVSRIPPGMGPSKLKHLLSIGRIYLARDEHQSFLFKEGWVEFIDKKVARRVAEMLNTRPIGGKYYSDLWTLTYLPKFKWTNLSDQIRIKEQLVRNSLEESKIYLGMVEKNSTN-QAK-Q-LKK Punst1 QAEQDRAGVIYISRIPPGMRPPKVRHLMSVGRVYLQQEDTKKPHFTEGWVEFKDKRVARAVAEMLNAQPIGGKWRDDVWTMKYLPRFKWNMLTEQIAVHRAKLRNELAQSRAYLQNVETARVL-EKR-K-REA Rhior3 EKARKKTGVCYLSRIPLFMPPSRVRELLKIGRIYLVPEDNNRRNYIEGWVEFKDKKQAKAVAEHLNMREIGGKYYAEMWNIKYLPKFKWHHLTEQMQARQQRLRNEIAQANRYIQNVEKAKML-EEK-K-RKR Rhoto1 KKGAKTPGLVYLSRLPPGMGPASVRDLMSVGRLYLEPANHQSHRFKEGWVEFEDKRVARSVAEMLNAQPIGGKWKDDVWTMKYLPRFRWDQLSEQFATQTSLLRFHLSSTRTYLTAVERARTN-KEK-A-ASR Rozal11 QKQIKRTGVVYLSRIPPFMKPQKLKNLLSIGRVYLVPEDNKRKNYIEGWVEFLDKRVAKRTVEYLNNTKIGGKYYDDIWTLKYLPKFKWQNLTEQLVKKENLLRMQMMQAKRFMQQVEIAKSI-EEK-R-KLR Sacce1 KKSKHKTGVVYFSSIPPYMKPAKMRQILTVDRLFLKKEDNKKNKYEEGWAEFIRKRDAKLCAETLNGNIIGGKYHDDILNVKYLPGFKWADLTEQIDIRQAKLEMEISQANKFIRNVEQSKMI-QNS-R-KR- Salro DGKKHERGIIYLSTIPPYMKPAKLRHIMSVDRIFLQPEDSKKTNFSEGWVEFIKKKTAKKVAAMLNGSLVGGKHHDFLWNMKYLPKFKWHHLQERMASRRYRLRAEMARMQQYLQQVHAAKRL-SAR-GVAQH Schco3 ------------------MRPAKVRHLMSVGRVYLQQEDTNKAHFTEGWVEFKDKKIARSVAELLNAQPIGGKFYDDVWTMKYLPKFKWNMLTEQVAVHTAKLRAELQQSRSYLKNVELARVL-DQR-K-KEK Schpo1 RKAIKRSGVIYLSRIPPYMAPNKLRQILSIGRVYLTPESNKRVMYEEGWIEFESKRVAKSVAELLNTNQIGGKYHDDIWNMKYLPKFKWHHLTEQIAARESRLKVEIEQGRKYMRNVENAKMI-EKK-R-SER Sorma EEAIKKSGVVYMSRVPPFMTPAKVRSLLEMNRIFLAPEDNKKKSFTEGWIEFVKKKDAKKVCELLNARPIGGKYRDDIWNLLYLKGFKWHNLTEQIAERASRMRAEISKTTKFVRNVERAKVQ-QAK-K-ASK Sphar -------------------------------------------MFVEGWVEYENKAHAKLAAEVLNNQRVGGKHYDDLWNVKYLPKFKWHHLTERKAVREKRLELEMRQATKYMDNVAKARMF-KER-K-AAA Spipu1 QSKVDATGVIYLSRVPPFMRPIKLRQLLAIGRIYLAPEDNKRQNYTEGWVEFLDKKVARQVATHLNGKQIGGKYYDDIWNMKYLPRFKWNHLTEQIKVREQRLKTEMAQAKRYVKNVGKAKMV-EER-N-RQK Sporo1 SKKVKQPGLIYLSRIPPGMGPGKVKHLLSVGRIYLALNDHQSHNFKEGWIEFLDKRVARSVADMLNAQNIGGKWHDDVWTMKYLPRFRWDQLSEQVATQTSLMRFHLNHSKQYLSAVEKARVS-NEK------ Stehi1 QAAQNKAGVIYISRIPPGMRPMKVRHLMSVGRVYLQQEDTKKAHYTEGWVEFKDKKVARSIAEMLNAQPIGGKWRDDVWTMKYLPKFKWNMLTEQVAVHTARLRVEISQSRSYLKNVELARVL-DER-K-RQA Tapde11 ------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------- Treme1 KKVKMTPGIVYISRVPPGMTPQKIRHLMSVGKVYAQPRDHTPANYTEAWVEFLDKSIGKTAAKVLNAQVIGGKWREDVWTMKYLSGFKWEMLGEQVQSHQARLRNEISKSRVYLRNVELARVL-DNI-K-DSK Trire2 DEAIRKSGVVYISRVPPFMKPNKLRSLLSINRIFLAPEDNKKKTFTEGWVEFVKKKDAKAVCELLNARPIGGKYHDDIWNLLYLKGFKWHNLTEQIAERSSRMRAEISKTTRFVRNVEKAKML-NAK-A-KAK Umbra1 QKDINKTGVVYLARIPPFMKPVKIKQLLSIGRVYLAPEDNNKQNFTEGWVEFKDKKKAKAVAAMLNTQQIGGKYYYDLWNIKYLPKFKWHHLTEQMKARQQRLSAEIAQATRFISNVEKSKMI-NEN-K-KRK Ustma22 KKKQRKLGIVYISRIPPGMTPAKVRHILSLGRIYLQ---HGVAHYTEGWIEFTSKKVAKAAAEMLNAQPIGGLFQDDVWTMKYLKGFKWHMLSEQMASHAARLRTELSQSAYYLKKVERARVQKDRR-K-RKA Walse1 DIKKSKPGMIYITRIPPGMTPSKVRAIMALGRIYLAPACPKNPRFVEGWVEFKKRKIARKVAELLNAQPIGGKYREDIWTMKYLGGFKWEMLSEHIASHAAKLRNELSQSKRYLKRVDKAKKQ-QER-R-QAK Zygro1 KKSKHKTGVVYLSTIPPYMKPTKMRQILTVDRLFLRREDNKKVMYVEGWAEFVRKRDAKLCAATLNGNIIGGKYHDDIMNLKYLPGFKWSDLTDQIDIRQSKLEMEISQANKYTKNVEKSKML-QNS-K-KRK [Cluster1963.fasta_al_trimmed; alignment length = 267] Allma1 RAALKRPKVCKACFYLAFETEIHETILFSRGEKVAIGASGGKDSTVLAHVLHLLNQRYDYGLDLVLLSVDEGITGYRDDSLATVQRNQYGLPLKIVSYGDLY-GWTMDEIVKQVGLKNN--CTFCGVFRRQALDRGAVLLGVDHIVTGHNADDIAETVLMNILRGDFARLQRCTAILNIKRSKPFKYTYEKEIVMYAYFKNLDYFSTECIYAPQAYRGYARTFLKDLEAIRPSAILDIIHSGECERCGYMSSQVCKACVLLEGLNRG Ashgo11 KALVKRPKVCKLCFFHVFETEIHNTILFQRGERVAVGASGGKDSTVLAYILKLLNERHDYGLEIVLLSIDEGIVGYRDDSLATVKRNQYGLPLKIVSYKDLY-DWTMDEIVACAGMRNS--CTYCGVFRRQALDRGAAMLDIHHVVTGHNADDMAETVLMNILRGDVARLEKSTAILTVKRSKPFKYAYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELMKNLEAVRPSCIIDIIHSGECERCGYLSSNICKACMLLEGLEKN Aspfu1 RAVIIRPKLCRACFLEVFETEVHETILFYPGERVAIGASGGKDSTVLASVLKTLNERYNYGLELCLLSIDEGIKGYRDDSLETVKRNQYDMPLEIVGYSELY-GWTMDQVVEQVGKKGN--CTYCGVFRRQALDRGAARLGIKHVVTGHNADDVAETVMMNLLRGDLPRLSRGTSIVTIKRSKPLKYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGSARTLIKDLEKIRPSSILDIVKSGECERCGYISSQICKACMLLDGLNKN Aurde31 RAIIKRPKICKECFFYVFETEVHNTILFKPGDRVAIGASGGKDSTVLAYVMKTLNERYAYGLELFLLSIDEGITGYRDDSLETVKRNQYGLPLKILGYDELY-GWTMDAVVAQVGKKNN--CTFCGVFRRQALDRGAASLGVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIKRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYAPDAYRGHARAFLKNLEAARPSAIIDIIHSGECKRCGYISSNLCKACTLLEGLERG Batde5 --MVKIPSSCKECFYFHLEKNVHNTILFKPGDRVAIAASGGKDSTVLAHVLCILNKRYNYGLDLCLLSIDEGITGYRDDSLETVKRNQYGIPLKILSYQDLY-GWTMDAIVKQIGLKNN--CTFCGVFRRQALDRGAALLKVDHVVTGHNADDIAETVLMNFLRGDLARLQRCTSIKTIPRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARAFLKDLESIRSSVILDIIHSGECNRCGYMSSNLCKACVLLEGLNRG Botbo1 RAIIKRPKICKECFFWVFETEVHNTILFKHGDKVAIGASGGKDSTVLAYVMKTLNERYDYGLDLYLLSIDEGITGYRDDSLETVKRNQYNLPLKILGYEELY-GWTMDKVVAKIGKKNN--CTYCGVFRRQALDRGAASLGVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARVFLKDLEAARPSAIIDIIHSGECTRCGYIASNLCKACALLEGLERG Botci1 RALIIRPKLCKACFIGIFEAEIHHTILFSPGDKIAIGASGGKDSTVLASVLKTLNERYNYGLELVLLSIDEGIKGYRDDSLETVKRNQYDMALKIVGYDELY-GWTMDQVVETIGKKGN--CTYCGVFRRQALDRGAKMLGINHVVTGHNADDVAETILMNLLRGDLPRLARSTSIVTVRRSKPLKYAYEKEIVLYAHHKKLDYFTTECLYSPEAFRGSARSLIKNLERVRPSAILDVVRSGECKKCGYMSSQICKACVLLEGLNKN Caeel PAKIRKAKLCGPCFSRNFEDDVHEAILFKRGERVAIGASGGKDSTVLAYVMKTLNDRHDYGLDLQLLSIDEGIKGYRDDSLLAVEKNEYGLPLTILSYRDLY-GWTMDDIVAKIGKKNN--CTFCGVFRRQALDRGAFKIGATKLVTGHNADDMAETLLMNVLRGDIARLERCTNIVTLPRAKPLKYCFERDIVMYARTNQLEYFYTECIYAPNAYRGYARKYVRDLEKVHPRAILDLIRSGECERCGYMTSQLCKACLLIEGLNTG Canalb1 KAVMKRPKLCKECFYNIFETEIHNTILFYRGEKIAIGASGGKDSTVLASILKTLNERYDYGLNLVLLSIDEGIKGYRDDSLATVKRNQYDMPLEIVSYKDLY-NWSMDEIVACAGIRSS--CTYCGVLRRQALDRGAEKLGIKHVVTGHNADDVAETVLMNLLRGDVARLESSTNIMTIKRSKPFKYTYQKEIVLYAHYKKLDYFSTECTYAPEAFRGTARELLKSLESIRPSCIMDIIYSGECEKCGYLSSNICKACMLLNGLEIN Cangl KAVLRRPKICKECFYYVFETEIHNTILFQRGEKVAIGASGGKDSTVLAHILKLLNDRHDYGVKLVLLSIDEGIVGYRDDSLATVKRNQYQLPLEIVSFRDLY-DWTMDEIVAIAGIRNS--CTYCGVFRRQALDRGAAKLDINHVVTGHNADDMAETVLMNILRGDVARLERSTAIITIRRSKPFKYCYQKEIVLYAHYKKLDYFSTECTYAPEAFRGTARELMKNLEAVRPSCIIDIIQSGECERCGYLSSNICKACMLLQGLEKN Capow SALLRRPKYCRECFYDAFETEIHTTILFVPGDRVAIGASGGKDSTVLAYVLKRLNDMYNYGIELFLLSVDEGITGYRDDSLETVKRNAYGIPLKIVSYQELY-GWTMDAIVKEVGLKNN--CTFCGVFRRQALDRGAALLGANKIVTGHNADDMAETVFMNILRGDAPRLQRCTNVVTLPRCKPFKFTYEKEIVLYAYFQKLDYFSTECVYSPQAFRGHARAFLKDLEALRPSSIVDVIRAGECVRCGYLSSQLCKACVLLEGLNRG Catan2 RASLKRPKICKACFYLAFETEIHTTILFHRGERVAIGASGGKDSTVLAYVLRTLNDRYDYGLDLVLLSVDEGITGYRDDSLATVRRNQYGLPLLVVSYKDMY-GWSMDDIVKQVGLKNN--CTFCGVFRRQALDRGAVKLGVDHIVTGHNADDIAETVLMNILRGDFPRLTRCTAITTLKRSKPFKYTYEKEIVMYAYFKQLDYFSTECTYAPQAYRGYARTYLKDLEALRPSAILDIIASGECERCGYMSSQVCKACVLLEGLNRG Cioin KALLKRPKLCKECFYWAFESEIHHTILFKEGEIVAIGASGGKDSTVLAHTLKVLNERYNYGLDLRLLSIDEGITGYRDDSLETVKRNEYDLPLTVLSYETLY-GWTMDAIVKKIGKKNN--CTFCGVFRRQALDRGAMMLGVNKIATGHNADDIAETILMNILRGDIARLKRCTAIITIPRVKPFKYTYEKEIVAYAYFKKLDYFSTECIYSPDAYRGHARAYLKDLESIRPSTIIDIIHSGECVRCGYISSNLCKACILLEGLNKG CocheC53 RALILRPKLCKTCFIAVFETEIHHTILFHRGEKVAIGASGGKDSTVLASVLKTLNERYDYGLDLILLSIDEGIKGYRDDSLETVKRNQYDMPLTILGYAELY-GWTMDQVVEQVGKKGN--CTYCGVFRRQALDRGASRLGVKHVVTGHNADDVAETVLMNLLRGDLPRLSRTTSIVTIKRSKPLKYAYEKEIVLYAHHKNLDYFSTECIYSPEAFRGSARALIKNLERVRPSAILDVVRSGECSKCGYLSSQVCKACVLLEGLNKA Coere1 RAIIRRPKICKECFFHVFETEVHHTILFSPGDRVGIGASGGKDSTVLAYVMKTLNERYSYGLELFLLSVDEGIAGYRDDSLETVKRNQYGLPLMIVSYEQLY-GWSMDSIVEAVGRKNN--CTFCGVFRRQALDRGALMLDLDHIVTGHNADDVAETILMNLLRGDIPRLGRCTEITTMGRSKPFKYAYEKEIVMYAYLKRLDYFSTECTYSPNAYRGYARQFLKDLESVRPSAIIDIIHSGECERCGYISSNVCKACALLEGLERG Conco1 KAIIKRPKICKACFYYVFETEIHNTILFNRGDRVAIGASGGKDSTVLACVMKVLNDRYDYGLQLFLLSIDEGITGYRDDSLETVKRNQYDIPLKIVSYRDLY-QWTMDDIVKEVGLKNN--CTFCGVFRRQALDRGAVMLGVDHIVTGHNADDIAETVLMNILRGDIARLERCTEICTIKRSKPFKYTYEKEIVMYAYFKNLDYFSTECIYSPNAYRGYARTFLKDLESIRPTAILDIIHSGECKRCGYISSNFCKACMLLEGLNRG Conpu1 KAIIKRPKICKTCFFDVFETEVHRTILFNRGDKVAIGASGGKDSTVLAYVMKTLNDRYDYGLDLYLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAVVSKIGKKNN--CTFCGVFRRQALDRGAASLGVEHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIQRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAVRPSSIIDIIHSGECRRCGYMSSNLCKACTLLESLEKD Copci --MVKRPKICRDCFFYVFETEVHQTILFKPGDRVAIGASGGKDSTVLAYVMKTLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAIVSQVGRKNN--CTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAARPSAIIDIIHSGECQRCGYMSSNLCKACTLLEGLERG Croqu1 RAIIKRPKVCRECFYLIFETEIHNTIMFRRGERVAIAASGGKDSTVLAHVMTTLNARYDYGLDLCLLSIDEGIKGYRDDSLETVKRNQYSLPLKVLSYDELYQGWTMDKVVENVGRKGN--CTFCGVFRRQALDKGADILGVDHIVTGHNADDVAETVLMNVLRGDIARLERCTEITTVKRSKPFKYAYEKEIVMYAYFKKLDYFSTECTYSPEAYRGHARALVKELERIRPSSILDIIYSGECSRCGSLSSQLCQACALIDGLNAG CryneH991 RALVKRPKVCKDCFFEVFETEVHNTIIFKRGERVAIGASGGK---VLAHVLSVLNKRYDYGLDLYLLSIDEGITGYRDDSLETVKQNEYGLPLKILSYSELY-GWTMDKIVEQVGKKNN--CTFCGVFRRQALDRGAAQLGVDHIVTGHNADDIAETVLMNIMRGDIARLARCTAVTTIKRSKPFKYAYEKEIVMYAYFKKLTYFSTECIYSPDAYRGHARVFLKDLEAVRPSAIVDIIHSGECLRCGYISSNLC------------ Crypa2 RAVIKRPKLCKTCFIRIFEEEVHHTILFYPGEQVAIGASGGKDSTVLASVLKTLNDRHNYGLDLMLLSIDEGIKGYRDDSLETVKRNQYDMPLKIVGYDELY-GWTMDQVVDTIGKKGN--CTYCGVFRRQALDRGSKMLGIKHVVTGHNADDVAETVLMNLLRGDLPRLSRATSIITVKRSKPLKYSYEKEIVLYAHHKKLDYFSTECIYSPEAFRGSARSLIKNLERVRPSAILDIVRSGECEKCGYMSSQMCQACMLLEGLNKN Debha1 KAVMKRPKLCKECFYNVFETEIHNTILFQPGDKVAIGASGGKDSTVLASVLKTLNERYDYRLELVLLSIDEGIKGYRDDSLATVKRNQYNMALEIISYKDLY-NWSMDEIVSCAGIRSS--CTYCGVLRRQALDRGAAKLGINHVVTGHNADDMAETVLMNLLRGDTARLEKSCTILTIKRSKPFKYSYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELLKSLEAIRPSCIMDIIYSGECENCGYLTSNICKACVLLAGLEMN Dekbr2 KAVMRRPKLCKVCFIAVFEEEIHNTILFHRGESVAIGASGGKDSTVLAAVMKTLNERYDYGLHLVLLSIDEGIVGYRDDSLATVKRNQYGMPLEIVSYKQLY-DWTMDEIVACTGIKSS--CTYCGVFRRQALDRGALKLGIHHIVTGHNADDMAETVLLNLLRGDTARIERSVSISTVKRSKPFKYAYEKEIVLYAHYRKLDYFSTECTYSPQAFRGTARTLLKNLESVRPSSILDIIRSGECERCGYLSTNICKACILLEGLNKS Dicdi RPVLKRPKICKECFYTVFEDEIHHTILFKRGDRVAIGASGGKDSTVLAEIMTLLNKKYDYGLDLFLLSIDEGITGYRDDSLETVKRNQYQIPLKILSYKELY-NWTMDDIVKEIGLKGN--CTFCGVFRRQALDRGAVMLKANKIVTGHNADDIAETVLMNLLRGDIPRLQRCVNIITLPRSKPFKYTYQKEIVMYAYFKKLDYFSTECIYAPNAYRGHARDFLKDLEAVRPSIIIDIIHSAECIQCGYICSNICMACDLLKNLNSG Dmel RAALKRPKLCKECFFAAFEAEIHHTILFRRGEKVAVAASGGKDSTVLAHVLKLLNERHNYGLELVLLSIDEGITGYRDDSLETVKQNDYQMPLKILSYEELY-GWTMDRIVAQIGRSNN--CTFCGVFRRQALDRGAKLLGVDSIATGHNADDIAETVLMNVLRGDTARLRRCTSIRTIPRVKPLKYSYEKEIVMYAHYKKLVYFSTECVFAPNAYRGHARAFLKDLEKVRPSVIMDIIYSGECTRCGFVSSQPCKACVLLEGLNRG Enthi NPVCTKTSICKQCFIDRVEKLVHQCILIYPTDHIVIGVSGGKDSTALATMLARIEKRWPSGAKYTLVAVDEGIVGYRDKSLECVRWLYLQLPLEIISYIETY-GMTMDEIVTR-GGKNA--CSYCGVLRRQCLEKAAIKVGANVIATGHNGDDVAETVLMNFLRGDVARLERCKSLKRIIRIKPFSLLTQKEVVLYAHYMKLQYFSVECTYAGTAFRGNARTFLQKTQILHPTIIHNCVISNECTVCGMQSSSLCQACKMMKELRNG Falba PPALKRPKVCKQCFLDIFEEEVHQTILFRPGMRVAIAASGGKDSTVLAHVLTRLDARHQYGVHFSLLSIDEGIAGYRDDSLAAVRRTPLGLPLEVVSHAELFAGWTMDRVVQTIGQKGN--CTYCGVFRRQALDRGAARLRADLIVTGHNADDIAETVLMNLLRGDIARLTRCTAIVTVPRCKPLKYAYEKEIVMYAFFRRLDYVATDCVYSPHAYRGHARVFLKQLETARPSAILDIIHSGECSVCGHVSSSVCAACQLVDRLNTF Fomme1 KAILKRPKICKECFFYVFETEVHNTILFKPGDRVAIGASGGKDSTVLAYVMKTLNERYNYGLDLFLLSIDEGITGYRDDSLETVKRNQYSMPLKILSYDELY-GWTMDAIVSKVGKKNN--CTFCGVFRRQALDRGATTLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIRRSKPFKYAYEKEIVMYAYFKRLDYFSTECIYSPDAYRGHARVFLKDLEAARPSAIIDIIHSGECERCGYMSSNLCKACTLLEGLERG Fusgr1 RAVVKRPKLCRDCFIQVFEDEVHHTILFFRGERVAIGASGGKDSTVLASVMKTLNERHDYGLDLVLLSVDEGIKGYRDDSLETVKRNQYDMPLEIVGYDELY-GWTMDQVVETIGKKGN--CTYCGVFRRQALDRGAKKLAIQHVITGHNADDVAETVLMNLLRGDMPRLSRSTSIVTVMRSKPLKYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGTARGLIKNLEKVRPSAILDIVRSGECIKCGYMSSQMCQACTLLEGLNKN Galma1 KAMLKRPKICRDCFFYVFETEVHNTILFNPGDRVAIGASGGKDSTVLAYVMKTLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAIVSQVGRKNN--CTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAARPSAIIDIIHSGECQRCGYMSSNLCKACTLLEGLERG Ganpr1 KPSLKRPKVCAECFFAIFETEIHNTILFKRGDKVAVAASGGKDSTVLAHVLKLLNARHDYGLDLYLLSIDEGITGYRDDSLETVKRNQYELPLLIVSYEELY-GWSMDAIVAEVGLKNN--CTYCGVLRRQALDRGATRLKVDHIVTGHNADDIAETVLMNFLRGDFARLQRCTQITTIPRSKPLKFAYEKEIVMYAYLKKLDYFSTECSYSPNAYRGNARTFLKELEAVRPQAILDIIYSGECTRCGYMSSGLCKACLLLEGLEQG Gloin1 RAIIKRPKLCKECFYYVFETEIHNAILFKKGDRIAIAASGGKDSTVLAHVMKLLNERYQYGLELFLLSVDEGITGYRDDSLETVKRNQYELPLKIISYSELY-GWSMDQIVKEVGLKNN--CTFCGVFRRQALDRGAVILNVDHIVTGHNADDIAETVLMN--------------------SK------------YVFF-----------------------------------------------------------VWVRG---- Hisca1 ------------------------------------------------------------------------------------------MPLEIVGY-----------VVRD-RTKGN--CTYCGVFRRQRLTGGAAKLGIGHVVTGHNADDVAETIVMNLLRGDLPRLARSTNIVTIKRSKPLKYAYEKEIVLYAHYQKLCYFSTECIYSPEAFRGSARTLIKDLEKVRPSSILDIVRSGECERCGYMASQICKACMLLEGLNKN Klula1 KAVMKRPKICKECFFSVFETEIHNTILFHRGERIAVGASGGKDSTVLAYVLKLLNDRHDYGVEIVLLSIDEGIVGYRDDSLATVKRNQYDLPLEIVSYKDLY-NWTMDEIVACAGIRNS--CTYCGVFRRQALDRGAAKLGIKHVVTGHNADDMAETVLMNILRGDVARLEKSTSILTIKRSKPFKYSYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELMKNLEAIRPSCIIDIIHSGECERCGYLSSNICKACMLLEGLEQN Lacbi2 KAMVKRPKICRECFFYVFETEVHNTILFKPGDRVAIGASGGKDSTVLAYVMKMLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAIVSQVGRKNN--CTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARVFLKDLEAARPSAIIDIIHSGECQRCGYMSSNLCKACTLLEGLERG Lenti61 RAILKRPKICKECFFYVFETEVHNTILFKPGDRVAIGASGGKDSTVLAHVMKTLNERYKYGLELFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAIVAQIGKKNN--CTFCGVFRRQALDRGAAILNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTIKRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAARPSAIIDIIHSGECRRCGYMSSNLCKACTLLEGLERG Malgl1 RAVLRRPKVCRACFFHVFETEVHQTILFRRGDRVAIGASGGKDSTVLAYVMKTLNERYDYGLNLFLLSIDEGITGYRDDSLETVKRNQYGIPLKVLGYKELY-GWSMDDIVASIGRKNN--CTFCGVFRRQALDRGAASLGVDHIVTGHNADDMAETVLMNVLRGDIARLERCTDIITIRRSKPFKYAYEKEIVMYAYFKQLDYFSTECIYSPNAYRGYARAFLKDLESIRPSSIIDIIHSGECTRCGYISSNLCKACVLLEGLNRG Mellp23 RAIIKRPKVCRECFYLIFETEIHNTIMFRRGERVAIAASGGKDSTVLAHVMTTLNERYDYGLDLCLLSIDEGIKGYRDDSLETVKRNQYSLPLKVLSYDELYQGWTMDKVVENVGRKGN--CTFCGVFRRQALDRGANILGVDHIVTGHNADDIAETVLMNVLRGDIARLERCTEITTVKRSKPFKYAYEKEIVMYAYFKKLDYFSTECTYSPEAYRGHARALVKELERIRPSSILDIIYSGECTRCGSLSSQICQACALVDGLNAG Mnele RAILKRPKLCKDCFYSVFEYEIHETILFKPGETIAIGASGGKDSTVLAHIMKLLNDRYDYGLNLVLLSIDEGISGYRDDSLETVKRNQYSLPLKILSYQELY-GWTMDAIVKEIGMKNN--CTFCGVFRRQALDRGAAMLKCDKIVTGHNADDIAETVIMNILRGDIARLGRCTSISTISRCKPFKYTYEKEIVMYAHFKKLDYFTTECIYSPNAYRGHARTFLKDLEKIRPRAILDIITSGECQNCGYIASSLCKACIMLDGLNRG Monbr SAALKRPKVCRECFYLAFEEEVHETILFERGDVVAIGASGGKDSTVLAYVLKTLNERHDYGLQLVLLSVDEGISGYRDDSLETVKRNQYALPLTIVSYKELY-GWTMDEIVAAVGRKSN--CTFCGVFRRQALDRGAHLLKVNKVVTGHNADDVAETVLMNILRGDIARLQRCTEIVTLPRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYAPNAYRGHARVLLKDLEKIRPSAIIDIIRSGE-----YISSQLCIASL---GLNKG Morel2 RAILKRPKLCKECFFHVFETEIHNTILFNKGDRVAIGASGGKDSTVLAYVMKLLNDRYSYGLDLILLSIDEGITGYRDDSLETVKRNQYQIPLLIVSYKDLY-GWSMDDIVKEIGRKNN--CTFCGVFRRQALDRGAIMLNVDHIVTGHNADDIAETVLMNILRGDLPRLQRCTSIITILRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGHARVFLKDLEAVRRTAIVDIIHSGECTRCGYISSNLCKACLLLEGLNKG Mucci2 RAVLKRPKICQECFYYVFETEIHHTILFQRGERVAIGASGGKDSTVLAHIMKTLNDRYDYGLDLYLLSVDEGITGYRDDSLETVKRNQYELPLKIVSYHELY-GWSMDEIVREVGRKNN--CTYCGVFRRQALDRGAVMLGVNHIVTGHNADDIAETILMNIFRGDIARLGRCTEIVTIKRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGNARTFLKDLEAIRPSAIVDIIKSGECERCGYMSSNLCKACLLLEGLNRG Mydma RAVLKRPKLCRECFYKVFEEEIHEAILFVPGDTVAIGASGGKDSTVLAHIMKTLNERYNYGLNLVLLSIDEGITGYRDDSLETVKRNQYDIPLKILSYKELY-GWTMDDIVKHVGRKNN--CTFCGVFRRQALDRGAMLVKANKIVTGHNADDVAETVLMNILRGDIARLQRCTAIKT----------------------------------------------------------------------------------------- Neucr2 RANIKRPKVCKGCFLTLFEEEVHHTILFYPGERVAIGASGGKDSTVLASVLKTLNERYNYGLELVLLSIDEGIKGYRDDSLETVKRNQYDMPLKIVGYDELY-GWTMDQVVETIGKKGN--CTYCGVFRRQALDRGAKMLDIKHVVTGHNADDVAETILMNLLRGDMGRLARSTNIVTVKRSKPLKYAYEKEIVMYAYHKKLDYFSTECIYSPEAFRGTARALIKQLERIRPSAILDILRSGECKRCGYMSSQVCQACMLLEGLNKN Orpsp11 KPVIKRPKVCKECFYFVFEEEIHQTILFKENEKVAIGASGGKDSTVLAYVMNLLNKRHNYKLDLVLLSIDEGITGYRDDSLETVKRNQYNLPLKIVSYKELY-GWSMDEIVKEAGNKNN--CTFCGVLRRQALDRGAVMLGAKHILTGHNADDIAETVLMNILRGDVPRLQRCTFITTIKRSKPFKYTYEKEIVMYAHFKKLDYFSTECIYAPNAFRGNARVFLKDLEKVRSTAI-------------------------------- Pench1 RAVIIRPKLCRACFIKIFETEVHETILFFPGERVAIGASGGKDSTVLAAVLKTLNERYNYGLDLCLLSIDEGIRGYRDDSLETVKRNQYDMPLDILGYSELY-GWTMDQVVEQVGKKGN--CTYCGVFRRQALDRGAARLGIRHVVTGHNADDVAETVMMNLLRGDLPRLSRGTSIVTIKRSKPLKYAYEKEIVLYAHHRQLDYFTTECIYSPEAFRGSARTLIKDLEKIRPSSILDIVKSGECERCNYISSQICKACTLLDGLNRN Phybl2 RAVLKRPKICQACFYHVFETEIHHTILFRRGERVAIGASGGKDSTVLAHVMKQLNEQYDYGLDLFLLSVDEGITGYRDDSLETVKRNQYELPLKIVSYGDLY-GWTMDDIVREVGLKNN--CTYCGVFRRQALDRGAVMLGVDHIVTGHNADDIAETVLMNIFRGDIARLGRCTEIVTIRRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARTFLKDLESVRPSAIVDIIHSGECERCGYMSSNTCKACVLLEGLNRG Picst3 KAVMKRPKLCKDCFYKVFETEIHNTILFLPGDKVAIGASGGKDSTVLASVLKTLNERYDYGLILVLLSIDEGIKGYRDDSLATVKRNQYEMPLEIISYRDLY-NWTMDEIVLCAGIRSS--CTYCGVLRRQALDRGAAKLGINHVVTGHNADDMAETVLMNLLRGDTARLEKSCAIITIKRSKPFKYTYQKEIVLYAHYKKLDYFSTECTYAPEAFRGTARELLKSLESIRPSCIMDIIYSGECEKCGYLSSNICKACMLLAGLEMN Plicr1 RAMLKRPKICKDCFFYVFETEVHNTILFKPGDRVAIGASGGKDSTVLAHVMKVLNERYNYQLDLFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDAIVAQIGKKNN--CTFCGVFRRQALDRGAAMLGVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTMICTIKRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAARPSAIIDIIHSGECERCGYMSSNLCKACTLLEGLERG Polpo RPVLKRPKICKECFYQVFEDEIHNTILFQRGDKVAIGASGGIDSTVLAEIMTLLNKRHDYGLDLFLLSIDEGITGYRDDSLETVKRNQYQIPLKILSYKELY-DWTMDEIVKEIGLKNN--CTFCGVFRRQALDRGAVLLGANKIVTGHNADDIAETILMNLLRGDVPRLQRCVNIVTLPRSKPFKYTYQKEIVMYAYFKKLDYFTTECIYAPNAYRGHARDFLKDLEAARPSVIIDIIHSAECNRCGYICSNICMACDLLRNLNAG Pucgr2 RAILKRPKICRECFYLIFETEIHHTIMFKKGEKVAIAASGGKDSTVLAHVMTTLNERYNYGLDLYLLSIDEGITGYRDDSLETVKRNQYSLPLKVLSYNELYQGWTMDKVVENVGRKSN--CTFCGVFRRQALDKGADLLKVDHIVTGHNADDVAETVLMNVLRGDIARLERCTEITTVKRSKPFKYAYEKEIVMYAYFKKLDYFSTECTYSPEAYRGHARALVKDLERLRPSAILDIIYSGECLRCGSLASQLCQACALIDGLNAS Punst1 RAMLKRPKICKECFFYVFETEVHHTILFKPGDRVAIGASGGKDSTVLAYVMKTLNHRYQYGLDLYLLSIDEGITGYRDDSLETVKQNDYDIPLQILSYDDLY-GWTMDRIVAQIGKKNN--CTFCGVFRRQALDRGAASLGVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIKRSKPFKYTYEKEIVMYAYFKKLHYFSTECIYSPDAYRGHARAFLKDLEAARPSVIIDIIHSGECARCGYISSNLCKACTLLESLESG Rhior3 RAVLKRPKICQQCFFYVFETEIHHTILFKRGEKVAIGASGGKDSTVLAHVMKTLNDRYDYGLDLYLLSVDEGITGYRDDSLETVKRNQYELPLKIVSYHELY-GWSMDEIVREVGRKNN--CTYCGVFRRQALDRGSAMLGIKHIVTGHNADDIAETILMNIFRGDIARLGRCTEIVTIKRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARTFLKDLESVRPSAII-------CTRCGYMSSNICKACMLLEGLNRG Rhoto1 RALIRRPKVCKECFFRVFETEVHHTILFRRGERVAIGASGGKDSTVLAYIMTLLNKRYDYGLDLCLLSIDEGISGYRDASLDTVKLNQYDLPLKILSYSELYGGWTMDKVVAEVGKKGN--CTYCGVFRRQALDRGADLLEVDHIVTGHNADDVAETVLMNVLRGDLPRLERCTAITTIKRSKPFKYAYEKEIVMYAYFKKLDYHSTECIYAPTAYRGYARALVKDLEAVRPSAIVDLIYSGECERCGSLTSQLCQACMLLEGLNRG Rozal11 RAIIKRPKICKECFFFVFETEIHQTILFKRGDKIAIGASGGKDSTVLAYVLKLLNERYDYGLDLFLLSVDEGITGYRDDSLETVKRNQYDLPLKIVSYEELY-GWTMDEIVKQVGLKNN--CTFCGVFRRQALDRGAALLNVDHIVTGHNADDVAETVLMNILRGDISRLGRCTAISTVPRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPMAYRGFARTYLKELEAIRPSIILDIIYSGECERCGYISSNVCKACVLLEGLNKG Sacce1 KALIRRPKLCKQCFCLVFETEIHNTILFQRGEKVAVGASGGKDSTVLAHMLKLLNDRYDYGIEIVLLSIDEGIIGYRDDSLATVKRNQYGLPLEIFSFKDLY-DWTMDEIVSVAGIRNS--CTYCGVFRRQSLDRGAAKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITIKRSKPFKYSYQKEIVLYAHYMKLDYFSTECTYAPEAFRGTAREYMKNLEAVRPSCIIDIIQSGECARCGYLSSNICKACMLLEGLEKS Salro RAAMRRPKLCRECFYAAFEEEVHETILFTPGDVVAIGASGG-----------------------------------------------------------------------------------------------------KAITTGEGGD--------------------------LPRSKPFKYTYEKEIVMYAYFKKLDYFSTECTYSPNAYRGFARTFLKDLETIKPSSIIDIIHSGECIRCGYMTSSLCKACVLLEGLNKG Schco3 KAILRRPKICKDCFFYVFETEVHNTILFQRGDRVAIGASGGKDSTVLAYVLKTLNERYDYGLDLFLLSIDEGIMGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDRIVSQVGKKNN--CTFCGVFRRQALDRGAAMLHVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTIKRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARVFLKDLEAARPSAIIDIIHSGECKRCGYMSSNLCKACTLLEGLERG Schpo1 RPALVRPKICKECFYYVFETEIHNVILFVRGERVGIGASGGKDSTVLAYVMKLLNERYDYGLELYLISVDEGIRGYRDDSLDTVKRNQYGLPMKIVSYADLYDGWTMDNVVARIGTKNN--CTYCGVFRRQALDRAALSLDIHHLVTGHNADDIAETILMNLLRGDVARLPRSTEITTTKRSKPFKYSYEKEIVLYAHYKKLDYFSTECTYSPEAFRGTARAMIKQLENIRPSSILDIIYSGECERCGFISSNICKACMLLEGLNKG Sorma RANIKRPKVCKGCFLTLFEEEVHHTILFYPGERVAIGASGGKDSTVLASVLKTLNERYNYGLDLVLLSIDEGIKGYRDDSLETVKRNQYDMPLKIVGYDELY-GWTMDQVVQTIGKKGN--CTYCGVFRRQALDRGAKMLDIKHVVTGHNADDVAETILMNLLRGDMGRLARSTNIVTVKRSKPLKYAYEKEIVMYAYHKKLDYFSTECIYSPEAFRGTARGLIKQLERIRPSAILDILRSGECKRCGYMSSQICQACTLLEGLNKN Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 RAVLKRPKICRNCFYAVFETEVHNTILFKRGDKVAIAASGGKDSTVLAHVMTTLNERYGYGLDLFLLSVDEGITGYRDDSLETVKRNQYKIPLKIVSYEELY-GWSMDAIVKEIGMKNN--CTFCGVFRRQALDRGAALLQVDHIVTGHNADDIAETVLMNILRGDFSRLQRCTAIRTIPRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARAFLKDLESIRPSAIMDIIHSGECERCGYMSSNLCKACVLLEGLNKG Sporo1 RAILRRPKVCKECFFEVFETEVHHTILFRRGERVAIGASGGKDSTVLAYIMTLLNERYDYGLDLCLLSIDEGISGYRDASLDTVKRNQYGLPLKILSYSELYGGWTMDKVVAEVGKKGN--CTYCGVFRRQALDRGAHILTVDHIVTGHNADDVAETVLMNVLRGDISRLERCTAITTIKRSKPFKYAYEKEIVMYAYFKKLDYHSTECIYAPTAYRGYARALVKDLEAIRPSAIVDLIYSGECQRCQSLSSQLCQACMLLESLNKG Stehi1 RAIVKRPKICKDCFFYVFETEVHNTILFKRGDKVAIGASGGKDSTVLAYVMKTLNDRYDYGLELFLLSIDEGITGYRDDSLETVKRNQYDMPLKILSYDELY-GWTMDRIVSTIGKKNN--CTFCGVFRRQALDRGASSLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTLICTIKRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARAFLKDLEAARPSAIIDIIHSGECKRCGYMSSNLCKACTLLEGLERG Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --------VCKECFFDAFESEVHATILFTRGMRVAIGASGGKDSTVLAYVLKVLNEKYDYGLDLFLLSIDEGITGYRDDSLETVKQNDYGMDLRILSYADLY-GWSMDDVVAQIGLKNN--CTFCGVFRRQALDRGALLEQADCIVTGHNADDMAETVLMNILRGDISRLGRCVSIVTVPRCKPLKYCYEKEIVLYAYYKDLVYFSTECIYSPNAYRGFARQYLKDLERVRPSAIIDIIRAAECSRCNYITSGLCQACVLLDGLNAG Treme1 RALVKRPKVCKSCFYSVFETEVHNTIIFHRGEKVAIGASGGKDSTVLAHVLTLLNQRYDYGLDLYLLSIDEGITGYRDDSLETVKQNEYGLPLKILSYNELY-GWTMDRIVEQVGRKNN--CTFCGVFRRQALDRGAAQLGIDHIVTGHNADDMAETVLMNLMRGDIARLGRSMALTTIKRSKPFKYAYEKEIVMYAYFKKLTYFSTECIYAPDAYRGHARVFLKDLEAIRPSAIIDIIHSGECLRCGYISSNLCKACALLEGLEAG Trire2 KAVVKRPKLCRECFINVFEDEVHHTILFYPGEKVAIGASGGKDSTVLASVLKTLNERHKYELDLVLLSIDEGIKGYRDDSLETVKRNQYDMPLKIVGYDELY-GWTMDQVVETIGKKGN--CTYCGVFRRQALDRGAKTLGIKHVVTGHNADDVAETVLMNLLRGDLPRLSRSTSIVTVKRSKPLKYAYEKEIVLYAHHKKLDYFSTECIYSPEAFRGTARSLIKNLEKVRPSAILDIVRSGECVKCGYMSSQMCQACTLLESLNKN Umbra1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 RAVLRRPKICKECFFYVFETEVHHTILFKRGDRVAIGASGGKDSTVLAHCMKVLNERYDYGLDLFLLSIDEGITGYRDDSLETVKRNQYQLPLKVLGYGELY-GWTMDDIVKSVGRKNN--CTFCGVFRRQALDRGAAALGVDHIVTGHNADDVAETVLMNVLRGDIARLERCTDIVTIRRSKPFMYAYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARTFLKDLEAIRPSSIVDIIQSGQCLRCGYISSNVCKACILLEGLEKG Walse1 --MIKRPKVCKDCFFFAFEEEIHKTITFKRGERVAIGASGGKDSTVLAHVMKTLNDRHDYGLNLFLLSIDEGITGYRDDSLETVKRNQYQLPLKILSYNELY-GWTMDRIVEAVGKKNN--CTFCGVFRRQALDRGASSLNISHIVTGHNADDVAETVLMNILRGDVSRLGRCVEITTIKRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPEAYRGFARTYIKDLEALRPSTIIDIIHSAECKRCGYISSNLCKACVLLQGLEKG Zygro1 KAIIRRPKICKSCFFHVFETEIHNTILFYRGEKVAIGASGGKDSTVLAYVLKLLNDRYDYGIELVLLSIDEGIVGYRDDSLATVKRNQYGLPLEIISYRELY-DWTMDEIVACAGVRSS--CTYCGVFRRQALDRGSSKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITIKRSKPFKYSYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELMKNLEMVRPSCIIDIIHSGECEKCGYLSSNICKACMLLEGLENN [Cluster1975.fasta_al_trimmed; alignment length = 123] Allma1 VSLQPSQFTHDVEEQLRRRLHAEVEGSFSGGYVISVVIGAGLVLPA-QGAAQYQLTYRAIVFK-PYKGEVLNAIVGFMAEVGPVNVFVSLPKQFKFNPSGVVRLRIQGTQTYPTKIDAIGSIK Ashgo11 ITLHPSYFGPRMREYLKTKLLQEVEGTCTGGYILCVLIERGRILPT-DGSAEFTVKYRAVVWK-PFKGEVVDGIVGFEVDVGPLSVFVSMPEDLTFNSGSNVRLKIVGARSEVNSIYAIGSIK Aspfu1 ISLHPSYFGPNMREYLINRLNEEEEGRCTG-FVICVMIGEGRVLPG-SGQAEYTIKYRAIIWK-PFRGETVDAIVGIFTLAGPLSVFIALLS---------KRGPVYGSKSSVSSLT------ Aurde31 ILLHPSYFGPRMQEFLEKKLYADVEGTCSGGYIIAVIIGRGIVLPG-SGQAEFVTRYRAIVFK-PFKGEVVDGVVGFFADVGPLSVFVSIHPDMRFDPNSNVRLKIVGTRVDATEIFAIGTIK Batde5 INLHPQFFGPQIRAFLTRRLYEEVEGICSGGYIISVVVGKGVLQSN-TGFAQFEILYKAIVFK-PFKNQVVDGLVGFWADVGPLQVFVSIPGYLKFDANANVRLRIVGTRVDATEIFAIGTIK Botbo1 ILLHPSYFGPRMVEYLETKLASDVEGTCSGGYIISVLVGKGMVLSG-TGQAEFIARYRAIVFK-PFKGEVLDGVVGFFAEVGPLNVFVSIGPDFKFDPNSNVRLKIVGTRVDATEIFAIGTIK Botci1 VTLHPSYFGRNMHELVTGKLLKDVEGTCTG-YIITIMISEGRILPG-SGLAEFTVGYRAVVWR-PFKGETVDAIVGFFADAGPLPLFVSIPRDIKFDANATVRVKIIGTRPEVGAMFAIGSIK Caeel VCLHPKYFGPNLNETIKMKLFNEVEGTCTGGFVIAVTIGHGLIQPG-RGFVIYPVRYKAIVFR-PFKGQVVDGVVGIFCDIGPLSCFISIPPDMEFDPNSEIRVKLIGTRVDANDIFAIGTLM Canalb1 LTLHPSFFGPQMDQYLREKLLSDVEGTCTGGYIVCVLVGKGRIIPS-TGMAEFEVKYRAVVWK-PFKGEVVDAVVGFFADVGPLSVFVSIPSDMKFNPSANVRLKIVGTRTDVNEIYAIGSIK Cangl VTLHPSFFGPRMKQYIKTKLLQEVEGSCTGGYILCVLIERGRILPT-DGSAEFNVKYRAVVFK-PFKGEVVDGTVGFEVQVGPMKVFVTMPQDLTFNAGSNIRVKIEGCISQVSSIHAIGSIK Capow IVLHPKYFGPRLRQALMEKLYTEVEGTCDGGFIVAITLGRGRLMAG-KGLVSYHVQYQAVVFR-PVKGEVMDAIVGFFAEAGPISIFVSMPSEYSFDVTSNVRLRIAGMRIDAESITTVGTIK Catan2 VELQPTLFTANIEDQLKRRLHDEVEGKYDSGYIVAVVIGSGLVLPA-MGSAQYSIKYRAILFK-PFKNEVVDVLVGFMCEIGAAEVFVSIPSAFKHDPKGVVRLQILNTTSAADRVHCIGTMK Cioin ILLHPRYFGPNLLETVKQKLFTEVEGTCTGGFVIAVTIGDGLIQPG-RGFVLYPIKYKAIVFR-PFKGEVVDAVVGLFTEIGPMSCFISIPADMKFDPESHIRLKIVGTRVDANDIFAIGSLM CocheC53 IQLHPSYFGPLIRQHIHRELLQKEEGSSTG-TIVCILISDGKVMPG-SGSAEYVVHYKAVVWR-PYKGEVMDGIVGFFVDCGSLQAFVGIPAEIKFDANATIRIKIKGLRSEVDKMYAVGTMK Coere1 ITLHPSFLGPRMREFVTKRLYKDVEGTCTGGYIIAVVIQIGKIIPG-LGSAEFEVKYSAILFK-PFRNEVLDAVVGFLANAGPLRIFVSIPADMKLDMNSNVRVKVNGARVDATNIIAIGTIK Conco1 IQLPPSYFGPGIRKFVEQKLHKDVEGTCSDGYIISVVVSQGKLIPG-AGQAEYTVSYSAVVLK-PFKSEVLDAVVGFFAEMGPLKIFVSIPEELEYNAESSVRLKILGIRTDATELYIIGTIK Conpu1 ILLHPSYFGPRMTQFLESKLYADVEGTCSGGYIIAVVIGRGMVLSG-SGQAEFVTRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDLKFDPNSNVRVKLVGTRVDATEIFAIGTIK Copci ILLHPSYFGPQMLSYLETKLYNDVEGTCSGGYIIAVVIGKGMVLSG-SGQAEFITRYRAIVFK-PFKGEVVDGVVGFFADVGPLSVFVSIHPDMKFDPNSNVRLKIVGTRVDATEIFAIGTIK Croqu1 INLHPSFFGPRTQAYLEDKLNRDVEGTCTGGYIIAVITSAGTIQPG-TGMAEFVLKYTAIVLK-PFKGEVVDGIVGFFVETGPLQAFVSIPSDLKFDPNANIRLKIVGTRIDATEIFAIGTIK CryneH991 ------------------------------RYIISVIIGEGKIIPS-TGQAKFKTRYTAIVMK-PFKGEVVDAKVSLFN----LWAFLR------------LSLVILLTRI------------ Crypa2 VTLHPSYFGRNMHELVTTKLLKDVEGTCAG-FIITIMISEGRILPG-SGLAEFTVGYRAVVWR-PFRGETVDAVVGFFAQAGPLMIFTSIPKNCVYDANATIRLKLIGIRTEVTEMWAVGTMN Debha1 LTLHPSYFGPQMDQYLRDKLLSDVEGTCTGGYIVCVLVGKGRVIPG-SGVAEFEVKYRAVVWK-PFKGEVVDAVVGFFADVGPLSVFVSIPSDMKFNPSANVRLKIVGTRTDVNEIYAIGSIK Dekbr2 LTLHPSYFGPNMKQYLRQKLLTDVEGTCTGGYIICVLVGKGRILTGNSGYAEFKVKYRAVVWK-PFKGEVVDAVVGFFADVGPLSVFISIPNDMKYTPSHTVRIKIIGTRSDVNSISAIGSIK Dicdi LHMHPKHCGPNLFTIATQQLYSEVEGTCTGGFIITITLSKGKVLES-SGYVVFNVKYKAIIFK-PFKGEVLDAIVGFFAEAGPLSIFVSIPSDMIFDAQSAVRLQIKGTRVDATEIFAIGSIR Dmel ILLHPRYFGPQLLETVKQKLYSEVEGTCTGGFVIAVTIGSGVIQPG-QGFVVYPVKYKAIVFR-PFKGEVLDAVVGMFAEIGPLSCFISIPADMQFCPNGNIRLKIVGTRVDATGIFAIGTLM Enthi IQVTPEHLNGGIEDYL-DKYISETTGYNKDCIVICVLIAEG------TGNVVFSVKFEAIVQK-IIRSEVVDGIIGVTVDVGSIHVTAS-VADCEYVEQSGVRVRSDVVDYNINGKKCLGTIE Falba LKLDPQYFGPDLKERVLDIFHQHVSGRCDEGYVVAVLIEPGRTIEG-EGLAVFRVKYRAIVLH-PFPQQVVSAVVGFFSRIGPVTIFTPIPDYFSYNGDISVRIRLISVTFENQHLVCNGTIN Fomme1 ILLHPSYFGPRMLQFLETKLYADVEGTCSGGYIIAVVIGKGMVLPG-SGQAEFVTRYRAIVFK-PFKGEVVDGVVGFFAEVGPLTVFVSIHPDMKFDPNSNVRLKIVGTRVDATEIFAIGTIK Fusgr1 VTLHPSFMGRNMHELVTGKLLKDVEGTCAG-FIISIMISEGRILPG-LGMAEFTVGYRAVVWR-PFKGETVDAVVGFFAHAGPLRLFVSIPNDVKWDPNATVRVKIIGTRTEVGEMWAIGSIK Galma1 ILLHPSYFGPRMLNFLESKLYSDVEGTCSGGYIIAVVIGKGMVLSG-SGQAEFITRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDMRFDPNSNVRLKIVGTRVDATEIFAIGTIK Ganpr1 ILLPPKAFGKSLREQLIQRLRDDKEGTCDGGYIVHILPPKGLVQAG-TGFAEYRLDYRALVFK-PFRNEVMDGVIGFFAECGPLQVFVSMPPEMKLETTNGVRLKIVSVKPDMGGLFAIGSIR Gloin1 YSTSPSFFTQNFETYLTEKLYKDVEGTCTGGYVIAVLISQGKVIPS-VGLAEFEVAYRAIVFK-PFKGEVVDGVVGFFADVGPLQIFVSIPQDLKFDPAKNVRIKIVGTRFDATDIFAIGTIK Hisca1 LTLHPTFFGSHVKEYLTQKLLDDVEGVCTG-YIVCVMISEGRVLPG-SGLAEYTIMYRAIVWK-PFKGETVDAIVGIFAEVGPLTVFVSIPPEIKWDPDATLRIKLIGLRNDVRNMFAIGSIK Klula1 ITLHPSFFGPQMKRYLMTKLLQEVEGTCTGGYILCVLIERGRILPT-DGSAEFTVKYRAVVWK-PFKGEVLDGIVGFEVEVGPLSVFVSMPEDLTFNSGSNVRLKIVGARSEVNSIYAIGSIK Lacbi2 ILLHPSYFGPRMLNFLESKLYSDVEGTCSGGYIIAVVIGKGMVLSG-SGQAEFITRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDMRFDPNSNVRLKIVGTRVDATEIFAIGTIK Lenti61 IHLHPSYFGPRMLQFLESKLYSDVEGTCSGGYIIAVVIGKGLVMPG-SGQAEFVTRYRAIVFK-PFKGQVMDGVVGFFADVGPLNVFVSIHPELKFDPNSNVRLKIVGTRVDATEIFAIGTIK Malgl1 TELHPSFFGPSMIEFLNRKLRDDVEGTCSGGYIIKVVVGQGKVMPG-TGLAEFRSRYQAIVLK-PFNGEVVDAKIGFFAEVGPLSIFVSLPIDYKFHPDSNVRVRIVGTRVDANEIFAIGTMK Mellp23 INLHPSFFGPRTQSFLEDKLNRDVEGTCTGGYIIAVLISAGTIQPG-TGMAEFVIKYSAIVLK-PFKGEVVDGIVGFFVEVGPLQAFVSIPSDLRFDPNANIRLKIVGTRVDATEIFAIGTIK Mnele ILLHPQYFGPRLIDIVKKKLFTEVEGSCTGGFVVAVTIGNGVIDQG-QGSVNFPVKYKAIVFR-PFKGEVVDAIVGIFCEVGPLTCFISIPADMVFNPDMEIRLKIIGTRVDANDIFAVGSLM Monbr VLLHPRFLDQNLEAILKTQLYSEVECKVHRGYVLAVIISEGRILFN-RGEILFNVTYTAVILR-PVPKQVIDTMVGIFVSIGPLTAFVSIP-DMTFDSDANVRVKIIAVRIAAQDIFITASLT Morel2 INLHPSYYGPHMKEFLMRNLHGDVEGTCSGGFIICVLISPGKVLPG-SGLAEFVVHYQAIVFK-PYKGEVVDAIVGFFADVGPLQVFVAMPSDFKFD--SNVRLKIVGLKHQATQINAVGTIK Mucci2 ISLHPSYFGPNMQGQLKDKLYADVEGTCTGGYVITVLIGKGKILPG-SGLAEFKVNYQAIVFK-PYKGEVLDAIVGFFADVGPLQVFVSIPTDMRFDANGNVRLKLVGTRVDATEIFAIGTIK Mydma ILLHPRYFGPNLLQTVKQKLFTEVEGTCTGGFVIAVTIGAGYIQPS-RGFVVYPVKYKAIVFR-PFKGEVLDAVVGLFTEVGPLSCFISIPTDMEFDPNSSIRLKIVGTRVDANDIFAIGTLM Neucr2 VTLHPSYFGRNMHELVTTKLVKDVEGTCAG-YIIAIMVSEGRILPG-NGLAEFTVKYRAVVWR-PFKGEVVDAIVGFFCQAGPLSIFVSMPEEIHFDPNATVRVKIGGLRTELGEMYAIGSIN Orpsp11 ILLHPQYFGPNIQACLYKRLYDEVEGTCSGGFIISVIISRGMLHPT-SGFAEFKIEYKAIVFK-PFKNQVVDGIV------------------------------------------------ Pench1 ISMHPSYFGPNMREYLIGRLNEEEEGRCTG-FVICVMIGEGRVMPG-IGQAEYTIRYRAIIWK-PFRGETVDAIVGIFTLAGPLSVFIAIPSDIKWEPNTVLRLKILGVKPDVAAINAIGTIK Phybl2 ITLHPSYFGPNMHSQLKDKLYADVEGTCSGGYIITVVIGKGKILPG-SGLAEFKVKYQAIVLK-PYKGEVLDAVVGFFADVGPLQVFVSIPNDMRYDPNGNVRIKLVGTRIDATEIFAIGTIK Picst3 LTLHPSYFGPQMDQYLRDKLLSDVEGTCTGGYIVCVLVGKGRIIPG-SGMAEFEVKYRAVVWK-PFKGEVVDAVVGFFADVGPLSVFVSIPSDMKFNPSANVRLKIVGTRTDVNEIYAIGSIK Plicr1 ILLHPSYFGPRMLSFLESKLYSDVEGTCSGGYIIAVVIGKGMVLCG-SGQAEFITRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDMRFDPNSNVRLKIVGTRVDATEIFAIGTIK Polpo --------------------------------------------------------------------------------------------------------------------------- Pucgr2 INLHPSFFGPRTSKFLEDKLNRDVEGTCTGGYIIAVLISAGTIQPG-TGMAEFVMKYSAIVLK-PFKGEVVDGIVGFFVEVGPLQAFVSIPSDLKFDPNANIRLKIVGTRVDATEIFAIGTIK Punst1 ILLHPSYFGPRMLQYLESKLHADVEGTCSGGYIISVVIGRGTILPG-SGQAEFVARYRAIVFK-PFKGEVVDGIVGFFCEVGPVTCFVSIHPDMKFDPSSNVRLKIVGTRVDATEIFAIGTIK Rhior3 -----------MQDKIQDKLYADVEGTCSGGYVVTVVLEKGKVLPG-SGLAEFKVSYQAILFK-PFKGEVLDGLV--------------IPNEFKFDVNGNVRLKLVGTRVDATEIFAIGTIK Rhoto1 LIMHPSYFNQSLRGYLSAELRRQVEGTCSGGYIIAVITHRGRIME--DGQAVFSVKYQAVVYR-PFRGEVVDGVVGIFVDVGPLQCFISVPPDFSFDPNANIRLKIVGTRVDATEIFAIGTIK Rozal11 VSLPPKFFGPGLKQILTRSLYMEVEGKFHGGYIISVVISRGVIEDT-FGAAKFLIKYKAIVFR-PFKNQVLDGKISHVSDCGPLRVFISFPDEFTFEPNSNVRVKIVNLSVQASEMIALGSIK Sacce1 ITLHPSFFGPRMKQYLKTKLLEEVEGSCTGGYILCVLIQRGRILPT-DGSAEFNVKYRAVVFK-PFKGEVVDGTVGFEVQVGPMKVFVTMPQDLTFNAGSNIRVKIEGCISQVSSIHAIGSIK Salro VLLPPRFLGPQLAESIRRKLYEDVESKCIGGYIVSVIIGEGEILVA-RGETLFPVTYRALVFR-PVKNEVVDAIVGIFAEVGPLRVFIHIP-NMVFDDTANIRIRILGVRVQASSIAATGSLA Schco3 ILLHPSFFGPQMTSFLEAKLYADVEGTCSGGYIIAVVIGKGMVMSG-SGQAEFITRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDMKFDPNSNVRLKIVGTRVDATEIFAIGTIK Schpo1 ISLHPSYFGPRMQDYLKAKLLADVEGTCSGGYIICVLIDKGRVVPG-QGFAEFEVKYRAVLWR-PFRGEVVDAIVGFFANIGPLNVFVSVPPDMKFDPTANVRLKIVGTRTDATEIFAIATMK Sorma VTLHPSYFGRNMHELVTTKLVKDVEGTCAG-YIIAIMVSEGRILPG-NGLAEFTVKYRAVVWR-PFKGEVVDAIVGFFCQAGPLSIFVSMPEEIHFDPNATVRVKIGGLRTELGEMYAIGSIN Sphar -----------------------------------------MIQEG-RGLATFNVKYKAIVLR-SFKGEVVDAEVGIFAQVGPLQIFVSMSNSLVYDETEQVRIRIITTRRDFKDTFAIGILL Spipu1 VRLPPQFFGPRLREHVERKLYDEVEGHIEGGHIICVLVGRGVLQPM-TGLAEFNVVYKALVLK-VFKNMVVDGVVGFWAEIGPLQMFVAIPSYYRFDPSANVRARIIGMRTDAREIFCVGTIK Sporo1 LIMHPSYFNPSLSAYLKLSLRRQVEGSCSGGYIIAV-GSEGQIAE--DGQAVFRLRYQAIVYR-PFRGEVVDGVVGVFVDVGPLQCFVSIPPDFSFDPNANIRLKIVGTRVDATEIFAIGTIK Stehi1 ILLHPSYFGPRMLQFLESKLYSDVEGTCSGGYIIAVVIGKGMVLGG-SGQAEFVTRYRAIVFK-PFKGEVVDGVVGFFADVGPLTVFVSIHPDMKFDPTSNVRLKIVGTRVDATEIFAIGTIK Tapde11 MKLHPSYFGPNIRQFLRQKLIADVEGTCDGGYIICVLIPPGKILTG-QGSAEFHVHYRAIVWK-PFKNEVVDAIVGFFADAGPVSVFVSLPSEMKFDPTANVRLKIVGTRTDATEI--VRSLP Thetr ------YFGPKLQERLKEALHAKVEGTCTGGYVITVTMGKGRIEEN-IGDVVFDVRYKAIVFK-PFTGEVLDAEVGFSCTVGPLNVFVPRLGDFSFDADAAVRIKIQAVNEHANDIFCIGTIS Treme1 ILLHPSYFGSQLEEYLRQKLYEDVEGTCSGGYIISVIIGEGKVLPG-TGQARFKTTYTAIVMK-PFKGEVVDGQVGFFAMVGPLQVFVSVHADMKFDPNASVRMQIVGCRIEANDIFAIGTIK Trire2 VTLHPSYFGRNMHELVTSKLLKDVEGTCAG-YIISIMISEGKILPG-NGLAEFTVGYRAVVWR-PFKGETVDAVVGFFAQAGPLRLFVSIPSDIKWDPNATVRVKIIGTRTEVGEMWAIGSIK Umbra1 ISLHPSFFGPNMQTQLVGKLYADVEGTCSGGYIITVVIGKGKILPG-SGLAEFKVKYQAIVFK-PFKGEVVDAVVGFFADVGPLQVFVSIPSDMRFDPNGNVRLKIVGTRIDATEIFAIGTIK Ustma22 TELHPSYFGPSMVEFLNQKLRDDVEGTCTGGYIIKVIVGQGKVIPG-SGLAEFNSTYQAVVLK-PFKGEVMDAKIGFFAEVGPLNIFVSIPIEYKFQPESNVRIKIVGTRVDANEIFAIGTMK Walse1 LHLHPSYFGPQTMDFINNKLYADVEGTCTGGYIIAVLPGSGTVLPG-VGTAEFVVKYTAIVYK-PFKGEVVDGQVGFFADVGPLQVFVSIPQDIKFDPSSNVRLKIVGTRVDATEIFAIGTIK Zygro1 ITLHPSYFGPRMKDFLKTKLLQEVEGSCTGGYILCVLIERGRILPT-DGSAEFTVRYRAIVFK-PFKGEVVDGTVGFEVQVGPMKVFVTMPQDLMFNAGSNIRVKIEGCISQVSSIHAIGSIK [Cluster1976.fasta_al_trimmed; alignment length = 185] Allma1 LLASSSSG-HKRTVRSVAFAP-ATASFDATIGIWYDYAATL--EGHENEAKAVAWSADGGLLATCSRDKSVWIWEDNDFECLSVLQEHTQDVKMVMW--HPTEEV-LASVSYDDTIRFWKDTVWGIDFDFITCSDDLSLRVWPIYSVAWNPWIASAAGDNTVDVNCVAWLLATCGDDGVVRIWQI Ashgo11 LLATGSATAHKKAVRSVAWRP-AAGSFDTTVSIWTELLAVI--EGHENEVKSVAWSHDGAYLATCSRDKSVWIWESEEFECNSVLQEHSQDVKHIVW--HASRLL-LASSSYDDTVRIWAETVWCSDFELCSGSDDTTVRIWAVYSVSWSGLIASVGSDGVLEINVVKWLLVTGGDDGCVNVWEL Aspfu1 IVATCSSG-HKRSVRTCAWKP-ATGSFDATVGIWWRFAVLL--DGHDSEVKSVSWSPSGMLLATCSRDKSIWIWEDNNFETVAVMQEHQGDVKCVAW--HPVEEC-LASASYDDTIRLWRETVWCVDWELVSCSDDRTVRIWSIYTVAWSGLIASVGADGRVEINHVTWVLITTADDGTVRVWTL Aurde31 LLASCGAG-HRRTVRSIAWTP-AAASFDSTISVWWECSATL--EGHETEVKRVAFNRDGTLLATCGRDKSVWVWEDADFECLSVQMEHSQDVKAVAW--HPTHDV-LASASYDDSIRLYLDTVWDIAFSLASVSDDLTIRIWPIYSIAWTGRIASAAGDGRVDVNTVRWLLATAGDDGAVRVWKL Batde5 ALISASGA-HSRTVRSVAYNP-ASGSFDGTVGIWMECVASL--EGHENEVKCVAWSASGVLLATCSRDKSVWIWEDDEYECSCVLQEHTQDIKAVRW--HPFEEI-LASASYDDTVKIWKETVWNIDFNIASVSDDKSLRVWTIYSVSWSGLIATASGDNTIDINSVVWYLASAGDDGIVRIWEY Botbo1 LLASCSSG-HTRTVRAIAWSP-ATASFDSTIGVWWECVSTL--EGHENECKSVAYSAEGNLLATSGRDKSVWIWEDAEFECITVQMEHSQDVKCVAW--HPTEEI-LASGSYDDTINIYADTVWCLSFSLASGSDDRTIRIWTVYSISWGGWLACTGGDGWIDVNVIAWVLATAGDDGVASVWKV Botci1 LIATATSG-HERSVRSAAWKPIATGSFDATMGIWWEFSIVL--EGHDSEIKNVAYSPSGQWLASCSRDKTIWIWEEDEFETVAVLQDHKADVKCVCW--RKDDEV-LASGSYDDTILLSRETVWNLDWELLSSSADMSIRIWPIYSISWSGRVVSTGGDGKIEINHVTWMVITTGDDGLTKAWCI Caeel ILASCGDS-HTRAVRSVAFSN-VSASFDASVVVYFAEVNKL--EGHESEVKCAVFSKSDEFLATCSRDKSVWFWQDEDFSVSSILQPHTQDVKQVAW--HPTEDL-LVSCSYDSSIRFYRFTVWSIAFDLVTVGEDHCIQLFPLYSVAWNDVIATGGGDCKIDVNHVAWLLTSASDDGTIRLWEL Canalb1 IIATASTT-HKRSIRSVAFKP-AAGSFDSTISVWWNLMAII--EGHENEVKAVDWNFQGQYLASCSRDKTVWIWELEEFECVAVLNDHSQDVKNVSW--HPSMNI-LASSSYDDTIRIYQQTVWCSKFELVSASDDLSVRIWPVYSVAWSGKIASAGSDGKIEINCVIWILVSAGDDGYVNLWKI Cangl LLATGSTTVHKKAVRSVAWRP-AAGSFDSTISIWMELLAII--EGHENEVKGISWSQDGCLLATCSRDKSVWIWEGEEYECISVLQEHSQDVKHVVW--HTKHNL-LASSSYDDTVRIWKDTIWCSDFSLCSGSDDSTVRVWQIYGVAWSGRIASVGADGVLEINTVKWMLITAGDDGRVNLWNY Capow LLAT---A-HSRTVRAVAWSP-ASGSFDFTVCIWFDCTATL--EGHESEVKGVAFAPAGNVLASCSRDKSVWIWDDGEFECAGVLHEHTQDVKFVRW--HPTEPI-LASASYDNTIKLYRETVWALAFNMVSVSDDRSLKIWTILSVDWSGLIATGGADNVIDVNSVAWLLASTSDDGSVHLWNI Catan2 LLASSSSG-HKRTVRSVAFSP-ATASFDATIGIWYEYAATL--EGHESEAKAVAWSSDGALLATCARDKSVWIWEDNDFECLSVLQEHTQDVKMVKW--HPSSEL-LISCSYDDTIRVWRDTVWAVDFDIASVSDDLSLRIWAIYCVSWCNWIATAAGDNTVDVNCVAWVLATCGDDGEVRLWKV Cioin LLATCGTG-HQRTIRKVGWSP-ASASFDATICIWFESAATL--EGHENEVKAVAWSQSGEYLATCSRDKSVWIWSEDDFECAGVLTVHTQDVKDIAW--HPFEPI-VASASYDDTIKLFKETVWSVSWSLVSGSDDKTIKVWPIYCVTWCDMIAACSGDNSIDVNAVSWLLASCSDDSCIKLWKI CocheC53 IIATACSG-HKRSVRTVSWKP-ATGSFDSSAGIWYQFSCIL--DGHESEIKCLSWSPSGQYLATCSRDKSVWIWEDDNFETVAVLQEHDGDVKCVAW--HPEEDL-LASASYDDTARLYRETVWWAEFELATCSDDRTVRIWAIYSVSWSGMIVSAGSDGKVEINHVAWVVLSTGDDGEVRVWTL Coere1 RLASCSSA-HKRTVRSVAFEP-ATASFDGTTAIWYDCVATL--EGHENEAKSVAWSASGQLLATCGRDKSVWIWEEGDFDCISVLMEHTQDVKMVLW--HPSEEV-LVSFSYDNTIRIWRDTVWGGAFSLASVSDDRTVRVWAIYSVSWGGYLATGCGDNTLDINCVEWWLATCGDDGAVRIWYL Conco1 CIASCSGA-HDRTVRSVCFNP-ASASFDSKTAIWYACVVTL--EGHENEVKSVAWSKGGNFLATCSRDKSVWIWEDGDFECLGVLQEHSQDVKMVRW--SPTSDV-LASASYDDTVKIWKDTIWGIDFNLVSVSDDLTLKIWTIYSVSWCGLIATGCGDNCIDINCVEWYLASAGDDGNVKIWEL Conpu1 LLASCSAG-HTKTVRSIAWAP-ATGSFDANIGVWWECATLL--EGHETECKGVAYSAGGELLATCSRDKTVWIWEDSDFECMGVLMEHTQDVKCVAW--HPSEQI-LASASYDDTIKLYADTVWALAWSLASASDDLTIKVWSIYSISWGGWLTSTGSDGKIDVNSVAWMFATAGDDGLVKAWVV Copci LLASCSAE-HMKTVRAVAWSP-ATASFDSNVGIWWECVGTL--EGHETECKSVAYSCTGTLLASCSRDKSVWVWEDAEFECMGVLLEHSQDVKCVAW--HPQEEI-LASASYDDTIKLYIDTVWSLAWSLASASDDQTVRIWSVYSVTWTGLLAAAGSDGVIDINAISWLLATAGDDQCIRVWDV Croqu1 ILASSSTG-HTRTVRAINWNP-ASGSFDSTVSIWWECTLSL--EGHESEIKGVAWNRNGKLLATSSRDKSVWIWEEAGYEVLSVLMEHEADVKSVCW--SPVEDL-LCSTSYDNHIQLYAETVWDASFSIASCSDDLSIRIWTIYSIDWTGYIATGGGDGKIDINAVRWLLASAGDDGTTRIWCL CryneH991 LLASCSTD-HKRTVRSIAWSP-ASGSFDSTVGVWWECVTTL--EGHESECKSVGFSSDGALLASCSRDKSVWVWEDADFECIAVMMEHSQDVKSIAW--HPHEEI-LASASYDSYIHLAYDTVWCLAWSLASGGDNGGIRLWSIFSLSWSGMLASAGEDGKIDINSVAWMLSSAGDDGSVKVWRV Crypa2 LLATCHAG-HARSVRTAAWKPLVTASFDSTAALWWEYTLVL--EGHESEVKSAAFSPAGQFLATCSRDKSVWIWEEDEWETVAVLSEHDGDVKCVAW--CPDVDV-LATSSYDDTVRVWRETVWGVQWELMTFSADRTIRVWDVYSASWSGLVASTGSDGVIEVNHITWMLITTGDNGVVKPWKV Debha1 LLATASTA-HKRSVRSVDFKP-ATGSFDSTISIWWNLMAII--EGHENEVKSVAWNYQGNLLASCSRDKTIWIWELEEFECISVLSDHQHDVKHITW--HPSQNL-LASSSYDDTIKLYKQTVWCSSFELVSASDDLSVRIWAVYSVSWSGKISSTGSDGKLEINSVSWVLVTAGDDGAINIWEP Dekbr2 LMATVSAGTHSKSTRCVAFKP-AVGSFDATVSIWWELLAVI--EGHENEVKAVDWSCDGKYLATCSRDKSAWIWENEEFECINVIQEHEQDVKNVKW--HPFENV-LATSSYDETCRVFRQTVWCSDFELVTCCDDAKVR--AVYSVDWNGLIASCGSDGILEVNCVKWELLTAGDDGNVSMWKI Dicdi ILATCANG-HEKTVRRVAWSP-AGASFDASTSIWFTHVSSL--EGHTYEVKSVAWDSTGTLLATCSRDKSIWIWQDNDFECLSINSGHGQDIKCVLW--HPNEEL-LASSSYDDTIKFWKDSIWDLAFNLVSCGEDKLVLFWPIYSIDWS--IVTGSADDSIDVNCTKWILASCGDDGFIKIWEL Dmel VFASCGEG-HKRTIREIRWSP-ASASFDATTAIWFECNATL--EGHENEVKSVSWSRSGGLLATCSRDKSVWIWEDDEFECAAVLNPHTQDVKRVVW--HPTKDI-LASASYDNTIKMFAETVWGIDFDLVSCSDDTTIKIWAIYDVSWCGLIATACGDDGIDVNSVQWQLISCSDDGTIKIWKV Enthi LLTP-----HNRTIRRVKCS--ACCSFDSTVSLW-TIIGTL--EGHESEVKCVDWSFGSNMVATCSRDKSVWLWKGIDYECCSVLTGHSGDVKTVLF--HPSGTI-LFSGSFDGTIKVWKGTVWDLKITIVAGCANGVIILYDIYSIDIN--VLVGSGDNAIDVNCVKWLSISVGDDNMLKIWKI Falba WLATCGGHLHQRTVRAVAWRH-VSVAFDASMVLWWTPVIEIEQEGHGAEIKSVAWSPDGSFLATCSRDKRVIVWAPLELEIASDLYGHGQDVKHVAWVDLPAEQC-LVSSSYDDTIMVWRLTVWATA--IASVSDDLSLRIWPIYSVSHCGLVATGAGDNAVELNSVAFVLATASDDGTIRIWRV Fomme1 LLASCSGG-HAKTVRCVAWAP-ATASFDANIAVWWECAALL--EGHETECKSVAYSSSGTLLASCSRDKTVWVWEDSDFECMGVLMAHTQDVKCVAW--HPTEEI-LASGSYDDTIKLYVDTVWSVAFSLASASDDLTIRIWSVYSVSWTGYLASTGGDGRIEINCISWLLATAGDDCIVRTWRI Fusgr1 LIATAHSG-HTRSVRSVAWKPLVTGSFDSTAGIWWEFTLVL--EGHDSEIKSCAFSPSGSYLATCSRDKSVWIWEDDEWETIAVLNEHEGDVKAVAW--CPDVDV-LASASYDNTVRIWRETVWGLQWELLTFSADNTIRVWDIYSVTWSGMVASTGSDGIVEVNHVTWMLVTTGDDGTVRPWQI Galma1 LIASCSAG-HSKTVRAVAWAP-ATASFDSNIGIWWECISTL--EGHETECKSVAYSPSGTLLASCSRDKTVWIWEEGDFETISVLMEHTQDVKHVSW--HPTEEI-LASASYDDTIKLYIETVWSLAWSLASASDDRTVRVWSVYSVSWGGWLASAGGDGTVDVNSAVWLLATTGDDGHTRVWRV Ganpr1 ELATCSGS-HKRTVRRVAWAP-ASCSFDATVSIWWPCVAVL--EGHENEVKGVTW--GDGLIATCGRDKSVWIWESDDFACLSVLQEHSQDVKSVHF--SPSSHL-LASCSYDDTVRLWFETVWELDWNLVASCDDGGVRVWSVYSVSWSGALATGAGDNAIDVNTVAWLLATGGDDGVVRIWRY Gloin1 VLASCGGA-HKRTIRSVAWSL-ATASFDALTGIWYECVATL--EGHENETKSVAWSSSGSLLATCGRDKSVWIWEDNDFECLSVLQEHTQDVKMVIW--HPTHEL-LASASYDDTIKIWRDTVWAIDFDLVSASDDKTIKFWCIYSVSWSGRVASGSGDNVIDVNCIQWWLATAGDDGIVRIWRF Hisca1 FVATCSAG-HKRSVRSCAWKP-ATASFDATVGLWWRFAVLL--DGHDSEVKSLSWSPAGTLLATCSRDKSIWIWEDNNFETVAVMQEHTGDVKWVSW--HPTEEC-LVSASYDDTIRLWRETVWCVEWELVSCSDDRTIRIWSIYSVAWSGLIASTGADGRIEVNHVCWVLISTGDGGDVKVWRL Klula1 IMATGSTTAHKKTVRSVAWRP-AAGSFDSTVSIWTELLAII--EGHENEIKCVAWSHDGELLATCSRDKSVWIWEGEEFECISVLQEHSQDVKHVIW--HQSLPL-LASSSYDDTVRIWKDTVWSSDFELCSGSDDGTVRIWAVYSVNWSGYIASTGSDGRLETNMVKWLLITAGDDGHVNVWKF Lacbi2 LLASCSAG-HMKTVRAVAWSP-ATASFDSNIGIWWECASTL--EGHETECKSVAYSSTGTLLASCSRDKTVWIWEDADFECMGVLMEHTQDVKCVAW--HPSEEI-LASGSYDDTIKLYIDTVWSIAWSFASASDDKTVRVWAVYSVSWGGWLGSAGGDGFVDANTVVWVLATAGDDGYTRVWRI Lenti61 LLASCSAG-HAKTVRAVAWSP-ATASFDSNIGVWWECMSLL--EGHETECKSVAYSASGNLLASCSRDKTVWVWEDHDFECMGVLMEHTQDVKCVAW--HPTEEI-LASASYDDTIKLYIDTVWSLAFSLASASDDTTIRIWSVYSISWGGWLASTGGDGIIDVNSVVWLFATAGDDGAVKVWKV Malgl1 -LSSGVSG-HKRTVRSVAWSP-ATASFDSTVGLWWECFGTL--EGHDSECKSVAFSYNGNLLASCGRDKSVWVWEDADYECIGVLIEHSQDVKCVIW--HPKEEI-LASASYDNTIKMYVDTVWSLSFSLASSSDDMTIWIWPIFSVNWAGKLVAAGADGKIDVNCVKWMIASAGDDGEIRIWT- Mellp23 ILASSSTG-HTRTVRSIQWNP-ASGSFDSTVSIWWECMMSL--EGHESEIKGVAWNRNGKLMATCSRDKSVWVWEDGGYEVLSVLMEHEADVKSVCW--SPKEDL-LCSTSYDNHLHLYSETVWDASFSISSCSDDLSIRIWTIYSIDWTGYIATGAGDGKIDINSVRWLLASVGDDGMTKVWSL Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr VLASSSGP-QKGTIRSLSWGR-AAASFDSTTCVWFECFATL--EGHENEVKGVAFSASGDYIAT-------WF--EEEFDCAAILAEHSQDVKAVAW--HPTRDL-LASCSYDNTIRFYRATVWKICFNLAAVGDDRTLRVYPIYSVDWDNILATAGGDNIVDLNGLAWLLATCADDG-LHVGNH Morel2 ILATCSGG-HKRTIRSVAWSP-ATGSFDATTGIWYECVATL--EGHENETKSIAWSNSGALLATCSRDKSVWIWEDNDFECLSVLQEHTQDVKMVAW--HPTEEL-LASASYDDTIKIWKDTVWAIDFAIVSASADQTLKIWCIYSVSWSGLIASAGADNTIDINSVAWWLASGGDDGSVRIWRL Mucci2 LLATCSGA-HKRTIRSVAWSP-ATASFDATTGIWWECVATL--EGHENEIKSVSWSATGALLATCSRDKSVWIWEDNDFECLSVLQEHTQDVKMVAW--HPKLEI-LASASYDDTIKIWKETVWSLDFNIVSASDDQTLRIWCIYSVSWSNYIASVSGDNSIDINGVSWWLSTVGDDGLVRIWRL Mydma LLASCSSQ-HNRTVRSVSWSP-AAASFDATVSIWFECIATL--EGHENEVKSVAWSCSGNYLATCSRDKSVWIWQEEEYECASVLSKHTQDVKAVVW--HPNIDI-VASCSYDDTINLYKETVWSISFNIVSSSDDKTLKIWPIYSVDWNDLIASCSADDSIDINCLKWILASCSDDMSIKIWNF Neucr2 LIATCHAG-HTRSVRSAAWQPLVTGSFDTTAGVWWELTLVL--EGHENEVKSVNYSPSGQYLATCSRDKSVWIWEEDEWETVAVLQEHDGDVKAVAW--CPDVDV-LASASYDNTVRLWRETVWGVAWELLSWGADEVIRVWDIYSVAWSGLLSSVGSDGVLEINHITWMLVTTGDDGVVRPWQV Orpsp11 LICSCGAV-HSRTVRSIAFSP-ASSSFDSTTAIWYEYIASL--EGHENEVKCVAWSASGSLVATCSRDKSVWIWEDDDFECLSVLQEHTQDVKMVTW--HPFDEI-LASASYDDTIRIWKDTVWAIDFDLVSVSDDMTIRIW------------------------------------------- Pench1 IVATCSSG-HKRSVRTAAWKP-ATGSFDATVGIWWRFAVLL--DGHDSEVKSVSWSASGMLLATCSRDKSIWIWEDNNFETVAVMQEHGGDVKCVSW--HPSEEC-LASGSYDDTIRLWRETVWFLDWELLSCSDDRTVRVWPVYAVAWSGLVASTGADGRIEINHVAWVLVSTADDGSVKVWTL Phybl2 LLATCSGA-HKRTIRSVAWSP-ATASFDATTGIWWECMATL--EGHENEIKSVAWSSSGALLATCSRDKSVWIWEDNDFECLSVLQEHSQDVKMVAW--HPKEEI-LASASYDDTIKIWKETVWSLDFNIVSASDDKTLKIWCIYSVSWSGLMASASGDNTIDINGVAWWLASVGDDGLVRIWRM Picst3 LLATASTT-HKRSVRAVSFKP-ALGSFDSTISIWWNLMAII--EGHENEIKAVGWNHNGSLLASCSRDKTVWIWELEEFECISVLNDHQHDIKHVVW--HPHQNL-LALSSYDDTIRLYKQTVWCSQFELVSVSDDMTARIWPIYSVAWSGKIATVGSDGKIEINSIIWVLVTAGDDGCVNIWKP Plicr1 LLASCSAG-HAKTVRALAWAP-ATASFDANIGVWWECVSLL--EGHETECKSVSYSASGTLLASCSRDKTVWIWEDADFECMGVLMEHTQDVKCVAW--HPIEEI-LASASYDDTIKLYMDTVWALAWALASASDDKTVRIWSVYSVTWGGWLATSGGDGVIDVNTVAWLLASAGDDGAVRVWRV Polpo LLASCGDA-HEKTVRRIAWSP-AAASFDASTSIWFNHISTL--EGHSFEVKSVAWDASGQLLATCSRDKSIWIWQDQDFECISINNGHSQDVKCVRW--HPSLEI-LASASYDDTIKMWQDTIWDIQFNLVSCSDDRSVCFWPIFSVDWSQLICTGGGDDSIDINSIRWILASSGDDSTIKIWSF Pucgr2 ILASSSTA-HTRTVRSIDWSP-ASGSFDSTASIWWECLMSL--EGHESEVKGVAWNRNGNLLATCSRDKSVWIWEDEGYEVISVLMEHEQDVKSVCW--SPVEDL-LCSTSYDNNIHLYAETVWDSSFSLASCSDDLSIRIWTIYSIDWTGMIVTCGGDGIIDINDVVWLFASSGDDGSVRVWRI Punst1 ILASCSAG-HTKTVRAVAWAP-ATASFDANIGIWWECVSLL--EGHETECKSVAYSSTGTLLASCSRDKTVWVWEDADFECLGVLMEHTQDVKCVAW--HPTEEI-LASASYDDTVKLYIDTVWSVAWALASASDDRTIRIWSIYSLSWSGWLASTGGDGKIDVNSVAWLLATAGDDGSVRVWHV Rhior3 LLATCSGA-HKRTIRSVAWSN-ATASFDATTGIWWECAATL--EGHENEIKSVAWSATGALLATCSRDKSVWIWEDNDFECLSVLQEHTQDVKMVVW--HPKLEI-LASASYDDTIKIWKETVWSIDFDLVSASDDETLRIWCVYSVSWSGYIASVGGDNSVDINGVSWWLATVGDDGMVRIWRL Rhoto1 TLASCSTS-HSRTVRSLSFSP-ATASFDSTVGIWWEAVDPL--EGHENECKSVAWSSDGRLLASCSRDKSVWVWEPADFECLAVLMEHSQDVKCVTW--HPTDEL-LASASYDDTIKLYGATVWTLSFSLASAGDDLVIKLWTVYAVDWAGRIITAGGDGRIDVNHVAWMFASAGDDGLVRVW-I Rozal11 YMLSCSSA-HDRTVRNICFSP-ASCGFDGVCNILFELIATL--EGHENEVKCVTWHSNGQLLATCGRDKSVWIWEDNEFECLSILQEHSQDVKKVLW--HPSDEI-LLSCSYDNTIRVWKAIVWAIDFNFVSVSEDSNIAIF------------------------------------------- Sacce1 ILATGSTTAHKKAIRSVAWRP-AAGSFDSTVSIWMDLLAII--EGHENEVKGVAWSNDGYYLATCSRDKSVWIWEGEEYECISVLQEHSQDVKHVIW--HPSEAL-LASSSYDDTVRIWKDTVWSSDFDLCSGSDDSTVRVWQVYNVAWGGLIASVGADGVLEINVVKWILATGGDDGIVNFWSL Salro -------P-----VR-MRFSP-VTASFDGTVCVWWECYATL--EGHENEVKDACFSASGEYLASCSRDKTVWIWETDEYDCCSILNDHTQDVKCLRW--HPSLDL-LASGSYDNTICLYRPTVWSLAFNLASASDDKTVRIWSVYSVDWCNLLATGCGDNHVDVNAVLWLLASASDDEVITLARF Schco3 LLASCSAG-HLKTVRALAWAP-ATASFDANIGIWWECVSLL--EGHETECKSVAYSSSGTLLASCSRDKTVWVWEDADFECMGVLMEHTQDVKCVAW--HPSEEI-LASASYDDTIKLYVDTVWSLAWALASASDDKTVRIWSVYSVTWGGWLASAGGDGVIDMNAIAWLLASAGDDGVARVWRV Schpo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma LIATCHHG-HTRSVRTAAWQPLVTGSFDTTAGVWWELTLVL--EGHENEVKSVNYSPSGQYLATCSRDKSVWIWEEDEWETVAVLQEHDGDVKAVAW--CPDVDV-LASASYDNTVRLWRETVWGVAWELLSWGADEVIRVWDIYSVAWSGLLASVGSDGVLEINHITWMLVTTGDDGVVRPWQV Sphar VTPTERGA-HTRTVRHVSWSH-ASASFDATTCVWWELAATL--EGHENEVKCAEWSSNSRRLVTCSRDKSVWIWEDCDFDCMSILQEHTQDVKCVKF--HPQEAI-IASVSYDDTVKLYGETIWCIDFDMVTSGDDKTIRIWPIFHCAFSERIATVAGDDSLDVNCVCWMLVTAGDDGCINIWRT Spipu1 LLATCSGA-HKRTIRSCAFSP-ATASFDASTAVWWECLATL--EGHENEVKSVSWSASGALLATCSRDKSVWIWEESDFECLSVLQEHEQDVKMVQW--HPTEEL-LASASYDDSIKIWRETVWGIDFNLASVSDDRTLRFWTIYAVSWSGRIATAGADNCVDVNSVRWLLATAGDDCVVRLWRY Sporo1 LLASCSTS-HTRTVRNLSFSP-GTASFDSTVGVWWEAVDPL--EGHESECKSVAWSGDGRLLASCSRDKSVWVWEPAEFECLAVLMEHTQDVKCVTW--HPHEEL-LASASYDDQIHLYAPTVWSVSFSLASTGDDLSLKIWSVYSLDWKGRIATCGGDGKIDINSIKWWFATAGDDGLIKVWKL Stehi1 LLATCSAD-HKKTVRSVAWSP-ATGSFDSTIGIWWECMASL--EGHETECKSVGFSASGNLLASCSRDKTVWVWEDADFECMGVLMEHTQDVKSIAW--HPREEI-LASASYDDTIKLYLDTVWSLAWSLASASDDCTVRIWTIYGVSWGGWLASAGGDGRIDVNTVVWLLATAGDDGVAKVWKI Tapde11 LIATASAN-HKRSIRSCAWKP-ATASFDGTAGIWWECAGLL--EGHENEVKSVAWSASGTLLATCSRDKSIWIWEYEDPECVSVMQEHSQDVKCVVW--HPSEEL-LASGSYDDEIRIWRDTVWSVDFALVSASGDSTVRVWDIYTVAWSNRIASAGEDGNIEINHLAWLLFSAGDDGVTNVWNV Thetr ALAVTGGV-HERTVRRIGWAP-AAASFDGTVSVWFALAHLL--QGHENEVKAAAWSASGALLATCSRDKSVWIWNGGAPACVAVLQGHSQDVKTVVW--HPSQDV-LVSASYDNELRLWIDTVWDVAFSLVSASSDGTLKIWDIYAVDWNGLIAAAGGDNAIDINAVAWLLASGADDGMIKVWQV Treme1 LFATCSTG-HSRTVRWISWAP-ASASFDSTVKIWWECVTTL--EGHESECKNVGFSHDGGLLASCSRDKSVWVWEDDDFECIAVMMEHNQDVKCLAW--HPKEEVNLASASYDSTIHLMFDTVWCLSWSLASGGDRGGIRIWPCFSLSWGGLLISAGGDGRIDVNCVAWMFGSVGDDGGVKIWRV Trire2 LIATAHGG-HSRSVRSVAWKPLVTGSFDSSAGVWWDFNLVL--EGHDSEIKGCAFSPSGTYLATCSRDKSIWIWEEDDWETIAVLNEHEGDVKAVAW--CPDVDV-LASASYDNTARIWRETVWGIEWELMTFSADGTIRVWDVYSATWSGLVASTGSDGVIEVNHITWMLVTTGDDGVVQSWQV Umbra1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 ILASCSGG-HQRTVRQVAWSP-ATASFDSTVGIWWDCVGTL--EGHESECKSVAFSYTGGVLASCSRDKSVWIWEDAEFECLSVLMEHSQDVKVVAW--HPNDEV-LASASYDDAIKLYIDTVWSISFSLASASDDLTVRIWTVYSVSWGGRIASGGGDGRIDVNCVSWMLASAGDDGSVKVWTL Walse1 ILASSSGE-HKRTVRALAWSP-ATGSFDATVGIWWTCTAVL--EGHESECKSVSFNSSSTLLASCSRDKSVWIWEGNEPECVSVLMEHTQDVKHVAF--HPHSDELLASASYDDTINIYKDTVWACEWSLVSVSDDKSITAWSVYALVWINIIATGGADGHLDINSLAYTLASAGDDGCVTVYNY Zygro1 MLATGSTTVHKKAVRSVAWRP-AAGSFDSTISIWMELLAII--EGHENEVKSVAWSHDGAYLASCSRDKSVWIWEGEEYECISVLQEHSQDVKHVVW--HPYLQL-LASSSYDDTIRIWRETVWSSDFEICSGSDDASVKVWAVYSVSWSGHIASAGSDGKLEVNVAKWMLATGGDDGYINLWNW [Cluster1979.fasta_al_trimmed; alignment length = 139] Allma1 FPAAAFGLGSWQLYRLRWKLGLIQETEAAL-FTKVSVDATLDPSTEFL-VGPRNGFHVVAPYTTTTLLVNRGWIAIVGLAKSSWTPDN-EPSKNQWYWIDVADMS-KRAQ-TQALVVEEVGLPLPKANLRNNHLEYAVT Ashgo11 IPVVSFYLGMWQLRRLKWKTELIAKCEDQLEYRRVVVKGAFRHEEEIF-VGPRKGYLLFTPFIRKDLLIERGWVSVVCLVRGRFQWDKTDEESRVWQVADIPAMA-AATG-TLPVHLQAIGVPVGKVELRNTHTQYMLT Aspfu1 IPVTAFILGTWQVQRLDWKTKLIAKFEDRLDYRRVYATGHFRHDQEML-IGPREGFIVVTPLERGEILVNRGWISVEGLLRNMFTPEN-KPEEGKFYFPDVHQMA-ELTG-SQPIWIEQTGIPIGRVNLRNNHSQYIFT Aurde31 IPIFTFGLGIWQIRRLKWKLGLIEELDDKLAFRKVRVRGTWDSARSIL-YGPKHGFDVITPLQRPNLLVNRGFVAVLGMLHSKYAPDN-DPEKGDWHWLDVQAMK-EHAG-GDAVLIDEIAIPVGIIELRNQHAVYAAT Batde5 IPAVTLGLGIWQVQRLQWKLHLIDQAQSRIQFTRVTVTGTFLHDKEIM-VGPRIGYFIFTPMVIAEVLINRGWIPVDGVIRQSWTISN-KPEKGEWYSIDLEKIS-QWTG-SLPIIVQMVGQPYRPAKLRNNHMEYAIT Botbo1 IPIFTFGLGTWQIQRLRWKVALIDELEEKVAFRKVLLRGTWDHAHTIL-VGPRLGYHVVTPLVRPDVLVDRGFVAVVGMLRGTFTPEN-VPEKGEWYWMDVERIK-EHAG-GEPVFIQEIGMPVGRIDLRNQHATYAVT Botci1 IPLTAFALGTWQVQRLDWKSKLIAKFEDRLDYRRIFATGHFRHDQEML-IGPRDGYLVITPLER-DVLVNRGWIEVEGLLRNYFTPDN-SPQTQEFYFPDVEQMA-KLTG-SQPVWIEETGIPIGRVNLRNNHTQYIFT Caeel IPVFAFSLGIWQTFRLKWKLDLIEHLKGRLEYCRVTVTGEFLHEKEFI-ISPRHGGHLITPFRLKNILINRGWLPLPAIVRPQFVGQN-VPEQGVWYYRDLNQMA-KHYG-TEPVLLDAAGGPIGGINVRNEHLNYLTT Canalb1 MPIISFALGCWQVHRLQWKTDLIAKCENNLEYRRFKCRGRFDYDQEMF-LGPRLGYLVVTPFIRKNILIERGWISIEALFRSFLQLEH-EQGSRLFHVPDVPAMA-KQSG-SLPIYCQMIGVPIAAIKFSNNHLQYLIT Cangl MPVIAFGLGTWQLKRLAWKTQLIAECETKLEYRKVLLKGKFLHEQEMF-VGPRKGYYLITPFIRNDLLIERGWIAVVCLIRGSLQWEQEDKQSRLWQVADIYDMA-AKVG-CTPIHFQALGVPIGKIDLRNNHLQYLVT Capow LPAITFGLGVWQVQRLKWKEGIVAEMEAKQAYSRFNVKGSFDHEREIY-IGPRLGFQVVTAFKMSDVLINRGWVPMTAVLRSKFIKLD-GSGSKRMIVADIPRMA-QILD-TEPVMLDVTTLPIPGVTVRNEHMQYALT Catan2 FPAAAFCLGSWQVYRLQWKLDLIERTNAALQHTKVAIDGRVDPSVEFR-VAPRPGFYAVTPFVLSSILLNRGWIAVVGLVK-AWSHDN-KPELGQWYWTDVTTMS-KLAS-TQPVLVDAVGLPIPRATFKNNHLEYAIT Cioin FPASAFGLGVWQWRRKAWKSNLIKELEQKTEYRPLIVRGTFDHSKELY-IEPRMGVLVITPFHVTDILVNRGFVPIVGLLRPPLSPKN-NPVRNHWFYKDLDQMG-SLTG-AEPILLDAVGGPIGGVSLRDEHLSYMIT CocheC53 IPVTAFILGCWQVQRLGWKTDLIARFEDRLDYRKVYATGVLRHDQEML-IGPREGYTVVTPLERRDILACRGWIKIEGLLRNMFTPKN-EPEKGKWFFPSVEEMA-EYSG-SQPVWVEETGIPIGRVNLRNNHTQYIFT Coere1 IPLIAFGLGTWQLFRLKWKLALLDDVNDRMEYRRVLVHGVFDHSAEML-VGPRPGFIVVTPLVREDVLVNRGWIRIVAFVRNAFTPKS-DPSSNEWYSIDLELMA-QRSN-SQEVLLDAIGIPLGTVDIRNNHLQYLIT Conco1 MPICSLYLGIWQVKRLQWKEDLIQKVEEKREYRPVILRGKYLCDREIL-VGLRSGYVVYTPFLREDILVRRGWVEIKGQVRNRYTPPN-SPKSGQWFYVNIEEMA-EFVG-SEPVLVDAIGVPIGRVSFYNHHAQYAFT Conpu1 LPVFAFGLGTWQVQRLQWKINLIDELEEKLIYRRVLLKGKWDHKHSLL-LGPRHGHHVVTPLVRSDILVDRGFITVVGMLRNRFTPDN-DPQGGHWYWADVDAMA-NYAG-GEPVYVEQIGVPVGRVDVRNAHLSYVIT Copci VPFFTFALGTWQLKRLKWKINLIDELEEKLVFRKVLLKGKWDHEHTML-LSPRHGVHVVTPLVRENILVDRGFVSVLGMIRNRFTPDN-EPDNGKWYWTDVEAMS-EHAG-GEPVFIEQIGLPIGRVDLRNAHLSYVIT Croqu1 VPLLTFGLGTWQVQRLKWKQHLIQDLEDKMEYRKIRVQGVFDHSKEIL-IESRLGYHLITPLVRSEILVNRGFIKVIGMLRSVFQPAN-KKEDNQWYFVDILELA-GFLE-TAPVLVDAIGDPIGRIQLRNMHATYIAT CryneH991 VPILTGFLGVWQLKRLRWKLDLIEEVDRNLSFRRVLIKGQFT-GPPIL-LGPQPGYHLILPFLRPGILVNRGFITVEGLLPTVWMHEN-KPETNEWFWKDVDKMA-EVCG-GEPVLVDALGIPVGRVELRNQHAQYAAI Crypa2 IPITAFALGTWQVYRLQWKTDLIAKCEDRLDYRRVVTRGRFRYDQEML-IGPRQGYMVVTPLEREDVLVNRGWISVEGLLRNMFTPDN-RPDKSEFYFPDVKQMA-ELTG-AQPVWIEATGIPLGRVNLRNNHAQYIFT Debha1 MPVISFFLGCWQVKRLKWKVALISKSENSLEYRRFKTKGHFDYSQEMF-LGPRTGYLVVCPFVRSNILIERGWIHIEALFRSNLQFDH-DMGSRLFYVPDVEVMA-EQSH-SLPVYCQMIGVPIAAVKFSNNHMQYMVT Dekbr2 APILTFCLGVWQVKRLKWKTKLIAQAEDRLLYRKVYITGKFDYTREVY-VGPRKGYTVVCPFVLSNILVERGWIGIECVVKSALQMKH-DKGARLFEYTDAYAMA-DELG-TRHSYLQAVGVPVGQIEYRNNHMQYLIT Dicdi FPVIAFGLGTWQVYRYDWKKRLIQRAKDRMEFRRVYLNGKVIDNQYVL-LGPRLGYYVISPLQLSDILLNRGWSAILGVISSAFTPTN-QPEKGQWYSLDVDAMA-DQLN-TEPLMINTMFKRFDNSSFHNKHMSYIGT Dmel IPATTFGLGCWQVKRKIWKEQLIKDLNKQLEYRLVKIRGRFLHDKEMR-LGPRNGYLIVTPFQLADVLVNRGWVSLTAVVRPQFTPDH-K--GNVYLYRDLARMC-AATG-AAPVFLDAVHAPIGGVTLRNDHLSYLVT Enthi ------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------MVNRGWIPVIGMLRSSFTPDN-VPEKGQWHWIDVGQLA-DTLR-ADPIVIDVTGLPMADANIRNNHLSYAVT Fomme1 MPILTFALGTWQIQRLKWKVNLIDELEEKLAFRKVRVKGRLDHAHTIL-IGPRKGVNVITPLIRSDILVDRGFVSINGMLRNRFTPDN-HPEKGEWYWVDVNALA-DYAG-GEPVFIEAIGVPVGRVEVRNSHAAYVFT Fusgr1 IPVTAFILGTWQVQRLGWKSELIAKFEDRLDYRRVRATGHFRHDQEML-IGPRDGYMVVTPLERENILVNRGWIDVEGLLRNMFTPDN-QPEKGMFYFPDVKQMA-ELTG-AQPVWVEATGIPYGRVNLRNNHAQYIFT Galma1 MPIFTFSLGVWQLKRLKWKIDLIDELEEKLVFRRVLLRGKLDHAHTML-LSPRHGVHVVTPLVRENVLVDRGFVSVLGMLRNLFTPDN-APAQGKWYWTDVEKMS-EYAG-GEPVFVEQIGIPIGRVDLRNSHLSYVIT Ganpr1 FPIATFALGCWQLYRLQWKLDLIDRANTRTEYRRMKLTGSFDYDNELY-IGPRIGYMVLTPFVLGSFLVIRGYIPIECLARMGMMIHN-KTESGEWHWLEREELKIRFLG-GELVILEMIPHPRALLEFRNKHLGYALT Gloin1 IPILTFGLGTWQVARLRWKVKLIEDYDDRLLYRRVKTSGKFLHDQELY-LGPRLGYYVITPLERENILVKRGWIPVEGLLKTWFVPEN-NPEKNQWYWLDVDTMA-QITG-SQPILVEQNGIPVGKVELSNTHLQYAIT Hisca1 IPITAFALGTWQVQRLDWKTKLIAKYEDRLDYRRVYATGRLRHDQEML-IGPRDGYLVITPLERGDVLVNRGWVAVEGLLRNMFTPEN-KPEVGKFYFPDVAQMA-ELTG-SQPIWIEETGIPIGRVNLRNNHAQYIVT Klula1 MPVISFYLGTWQLRRLKWKTNLIASCEDKLEYRKCTMTGRFLHDEEIF-VGPRKGYVLYTPFIRKDILIERGWISITVLVRTSMQWKKEDRESRLWQVLDIKDMT-EMTH-TSPIHYQALGVPIGKIDLKNNHLQYLIT Lacbi2 IPFFTFALGTWQLKRLKWKVNLIDELEEKLVFRKVVLRGTWDHSHTII-LTPRHGVHIVTPLVRQNILVDRGFVSVLGMLRNLFTPDN-KPEDGKWYWTDVDAMA-DYVG-GEPVFVEQIGIPIGRVDLRNAHLSYVIT Lenti61 IPIFTFGLGTWQVQRLKWKVALIDELEEKLAFRKVALRGRWDVSHLML-LGPRNGYHVVVPLVRSDVLVDRGFVAVLGMLRNNFTPEN-HPDKGEWYWADIDAMA-AHAG-GEPVFVEEIGVPIGRVDVRNSHLSYIVT Malgl1 LQCFAMYLGFWQLRRLKWKVSLIDELEDKLEYRLFQVHGHFDMSRVLF-VGPRRGYNVIMPFKRSSILVNRGFVTIVVLLPSRLALPN-EPHNNLWLQIHPSQMA-HWLN-EQPVYMEEIGTPVGRIELRNQHAEYAAT Mellp23 VPLLTFGLGTWQVQRLKWKRRLIEDLEHKMEYRKVRLEGRFDHSKEIL-IESRLGYHLITPFIRTEILVNRGFIKLIGMLRSLFQPEN-KKESNQWYFVDILEIA-NHLN-SAPVLVDAIGNPIGRIQLRNMHVTYIVT Mnele IPVVCFCLGWWQIERRKAKLQLIADIESRYEYTPVKFTGKFDYSKEFY-LGPRGGYHSIVPFTLDNILVDRGYVSLSGYIRASLAPAS--GTTQTYIWRDTEMMA-KKAD-TLPISVELMDVPLPRLLLHPGPALQQLV Monbr VPVVTFGLGTWQIFRKQQKEELIATLEAKLEYERVAVTGTFLHDQEML-VGPRAGVQVITPFRLADILVNRGFVPLEGIVRTAFVPDN-HPEQNTWYWIDVFTMA-SNRS-ALPVLIDATGFPLGGITVRNEHLSYIIT Morel2 CPIITFGLGTWQVQRLRWKVDLIENLEDRMEYRKVKVAGKFRHDQEIL-LGPRPGYFLITPFERTNILVRRGWVPLEGLLRSSFVPEN-NPEKNEWYSLDLEAMA-KQSD-SQPVVVEMIDIPVGRVELRNHHKEYIVT Mucci2 -------------------ASAATSLEGQLAQRGHSA----TQAHQIL-LGPRAGYFVITPFERDNILVKRGWISVVGLIRNTFTPDN-DIKRNQWYWADVDTIA-KMFN-TQPIMIERVGIPVGRVEVRNHHLNYLIT Mydma IPITAFCLGTWQIKRLAWKKELIREMEARTEYRRVIVRGKFDHTKEVF-LGPRSGYHIVTPFVL-NILVNRGWV-LTGLIRP--QFTPVKNDSLTFHYCDLDTFS-TILH-THPVLIDA-GGPLGGVNIRNEHLQYIVT Neucr2 IPITALFLGTWQVYRLKWKTDLIAKCEDRIDYRRVYAEGVYRHDQEML-IGPRQGYMVVTPLERGDVLVNRGWVSVEGMLRNMFTPDN-RPDIGEFYFPDVKQMA-ELTG-SQPVWIEQTGIPIGRVNLRNNHAQYIFT Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------- Pench1 IPVISFILGTWQVQRLDWKTKLIAKFEDRLDYRRVYAIGRLRHDKEML-VGPRDGFIVVTPLER-EVLVNRGWISVEGLLRNMFTPDN-KPEEGKFYFPDINQMA-EKSG-SQPVWIEQTGIPIGRVNLRNNHSQYIFT Phybl2 IPFITFGLGTWQVQRLRWKVGLIQRLEERMEYRRVTVKGHYRHDQEML-LGPRVGYFLVTPLERPNILVKRGWVPVEGLLRNSFTPDN-DIARNQWYWVDVETMS-DLMH-TEPLLVERMGIPVGRVEVRNSHMSYIIT Picst3 MPVISFVLGCWQVKRLQWKTALISKCENALEYRRFKCKGHFDYDQEIF-LGPRLGYLVITPFVRTSILVERGWIHIEALFRSYLQFDH-QDGARLFNVHDVPEMA-KQSG-ALPIYCQMIGVPIAPLKFSNNHLQYLVT Plicr1 VPIFTFGLGTWQLQRLQWKIALIDELGEKLVYRRVLLRGKWDHTHSIL-LGPRVGYHVVTPLVRSDVLVDRGFVSVLGMLRNNFTPDN-HPEQGVWHWADVDAIA-DYAG-GAPVFLEQIGIPIGRVDLRNAHLSYVIT Polpo FPCIAAGLGTWQVYRYQWKKDLIEKAKENVEFRRVQLKGQYANAENNMHLGPRVGYYLITPFILDSILVNRGWV-IEGLVGSAFTPDN-QPAQNQWYYINAEEMA-RESGASAPIIVNALLKRFNTSNFYNKHMSYIFT Pucgr2 VPILTFALGTWQVQRLGWKKELIKDLENKMEYRKVKLTGRFDHSKEIF-IESRLGYHLITPFHPHNILVNRGFIKVIGMLRSFFQPNN-SKDSNQWYFVDIQEIA-EHLE-TAPILVDAI------------------- Punst1 IPISCFALGTWQVKRLKWKVALIDELEEKMAYRRVVLSGRWDHAHTVL-VGPRNGYHVVTPLVRENVLVDRGFVTVYGIIRNRFTPDN-HPENGEWHWLDIGALA-EHAG-GEPVLIEEIAIPVGRVDVPNSHLSYLIT Rhior3 IPFVTFGLGTWQLQRLRWKVNLISTLEDRLEFRKVYARGRYRHDQEIL-LGPRAGYFVITPFERDNILVKRGWISVVGLIRNSFTPDN-DIEHNQWYWADVDTIA-QLTH-SQPVMVERVGIPVGRVEIRNHHLNYLIT Rhoto1 MPVFTFGLGVWQIKRLNWKVDLIHQLDDKLAWRKVFVTGTLDHEHSIE-LGPKLGYHVVTPLVRGEILVNRGFVKLVGMLRNSFTPVN-QPEKDQWVFANIAEMA-RCTG-AEPVLVDQIGIPVGRIELRNMHATYAAT Rozal11 CPLICAGLGVWQMQRLEWKLSYIEDVKEQMIWRYINIKGKFE-EESIL-VGPRVVFYVVTPYVLEN---------IGGLDDKWFKADN-----------------------SKPETLKVI------------HEKVNLF Sacce1 MPIISFYLGTWQVRRLKWKTKLIAACETKLEYRKVILTGHFLHNEEMF-VGPRKGYFLFTPFIRDDVLIERGWISVVCLVRGSLQWAKKDPNSRLWQVPDIYDMA-RSSG-CTPIQFQALGVPIGRIDLKNNHLQYLVT Salro MPAIAFGLGTWQIFRKKQKEELIAVMEGKLEYERVSVEGEFLHDQEII-VSPRPGAQIITPFRRADILVNRGFVTLEGIVRGAFVPEN-EPEKDEWRWIDIKTMS-EARN-TKPILIDVVGMPLGGINIRNEHMQYIIT Schco3 FPVFTFALGSWQLKRLKWKIDLIDELTEKLTWRKVKANGKWDHAHTML-LGPKNGYQVITPLMRQDVLVDRGFVPVVGLIRNTFTPDN-DPKEKFWYWRDLDAMA-EYAG-GKPVFFEEIGIPVGRVNLRNSHLSYVLT Schpo1 VPIVTFALGTWQVKRREWKMGIINTLTERLEWTRVLLRGVFCHDQEML-VGPRPGYHVVTPFILDDILVNRGWIAIEGLLRPRFMMKN-EPEKNSFYFLNVREFA-QLKG-TLPILITELGLPLGHVEIFNSHTEYIIT Sorma IPITALFLGTWQVYRLKWKSELIAKCEDRIDYRRVYAEGVYRHDQEML-IGPRQGYMVVTPLERGDVLVNRGWVSVEGMLRNMFTPEN-RPDIGEFYFPDVKQMA-ELTG-SQPVWIEQTGIPIGRVNLRNNHAQYIFT Sphar ------------------------------NYR--------VHIHAIS------------------VLVNRGWVPLDAIVRNAFV-KN-DPQRNQWFYRDVFAMA-KHTG-AQPYIFDATSPDIGVLNL---------- Spipu1 VPLTTFCLGSWQLYRLDWKLDLIRKWEERMEYTRVTLKGQFT-SPDIH-LGPRVGYFLISGFRNDDVLVNRGWVPVEGVLKSIFMPKN-RPDKNEWYWMDLKGMA-SHVG-AEPILVELLTPPFRRTNFRNNHLQYAIT Sporo1 MPIFTFGLGAWQIKRLKWKVDLIDQLDKKLAWRKVYVTGTFDHENSIV-LGPKIGYHVITPLVRGDVMVNRGFVKIVGMLRNSFTPQN-DPSKDQWVFSNIAEMA-KYTG-SEPVLVDEIGIPVGRIELRNMHATYAAT Stehi1 VPILTFALGTWQLQRLQWKIALIDELTEKLIYRKVILRGKWDHAHAMP-LGPRLGYHLITPLVRTNVLVDRGFVAVCGMLRNAFTPDN-HPEQNLWYWTDVDAMA-EFSG-GAPVLVEEIGIPVGKVDVRNSHASYVVT Tapde11 MPIAAFALGTWQVKRREWKLALIREYSDKLEALPIRLEGQFLHAKEML-VGPRTGFLVITPFVDRDILVNRGWISISGLLRNYFTPNN-DYSKGQYYFIDIVKMS-LQTG-TEPMLL-EMGQPIGKVHLVNNHMQYIVT Thetr LPITFAGLGTWQVYRHQWKQDLLDRVAQRIEYTRVVTHGSFDHSAEIL-MVPKPGAHVLTPLVRDDVLVNRGFVPVAGILRNSFTPDN-KPESGTWYWRDIDALV-ETLD-VLPFVVEAGGVTV--ISVPNNHWHYAAT Treme1 VPLLTGALGVWQLKRLKWKLELIDEVEKNMTYRRVLVKGTFT-GPPIL-LGPQPGGK---SQRRRTILVNRGFITLEGILSS-WSPDN-RKEKNEWYWKDLKGMV-EFCG-GEPVLVDAIGIPVGKVELRNQHASYAAT Trire2 IPVTAFVLGTWQVQRLDWKTKLIAKFEDRLDYRRVLATGRFRHDQEML-VGPRDGFMVITPLERKDILVNRGWISVEGLLRNMFTPEN-RPDKGEFYFPDVHQMA-ELTG-SQPVWIEATGIPFGRVNLRNNHAQYIFT Umbra1 IPFITFGLGTWQVQRLRWKTHLIEDMEDRMEYRRVKVSGVYDHAHEML-LGPRSGYFLITPLVRENVLVKRGWVPVEGLLRNSFTPDN-DIVNNQWYWVDVETMA-EITG-AEPVVIERVGIPVGRVEVRNHHLQYIIT Ustma22 IPIFTFGLGYWQIKRLKWKVSLIEELEDKLDFRLVSVKGSFDHSRTMF-VGPRMGYHVVVPFRRSEILINRGFVSFVALLPNTFTPNN-VPEKGSWFHVNPSQMA-EWAS-SQPVYLEQVGVPVGRIELRNQHAVYAAT Walse1 IPIFTFYLGCWQVKRLDWKLNLIEELDEKLEYRKVSTSGTLS-ADSIQ-VKPRTGIHLIQPLLRK-ILINRGFLSITGMLRNFFTPNN-NPSLGEWFWVDLPAIA-NHFS-QRDVLIDEIGIPVGRIELRNQHAIYALT Zygro1 MPVISFYLGTWQVRRLEWKNNLIARCESRLEYRKVLLKGHFVNEEEMF-VGPRKGYILFTPFVRKDVIVERGWISIMCMVRGSFQWEKEDQNSRLWQVPDVLEMA-SVTG-STPLHLQAVGVPIGKIDLRNNHLQYLVT [Cluster1988.fasta_al_trimmed; alignment length = 181] Allma1 DPEQVR-LMEEMCILVDGDDKVVGFDTKKNTHIMANIE-KGLLHRAFSVFLFN-HENKLLLQQRADEKITFPGYWTNTCCSHPLGAKTAAVRKLDHELGI--TGVAA-SELQFLTRIHYLAPDATWGEHEVDYIFIAKKDSPNEVKATRYVTPDELRALFLTPWFRLICENFLF-DWWKHL Ashgo11 DEEQIK-LMNENCIIVDWDDEPIGAGTKKLCHLMENID-KGLLHRAFSVFVFS-ADGRLLLQQRATEKITFPDLWTNTCCSHPLGAWTAAVRKLEHELGIPPAQTLKRGKFHFLNRIHYMAPNGPWGEHEIDYILFYRVSNPNEVRNSRWVTQHELKEMFFTPWFKLICQSYLF-EWWGQL Aspfu1 DEEQVR-LMDEVCIVLDDDDKPIGSASKKACHLMTNID-RGLLHRAFSVFLFD-SNNRLLLQQRASEKITFPDMWTNTCCSHPLGVKRAAQRKLDQELGIKAEQVPL-EKFEFFTRIHYKAPDGKWGEHEVDYILFIQADNPNEVRDTKYVSAQELKQMFFTPWFKLICNSMLF-EWWSYL Aurde31 DPEQSR-LMDERCIVVDEQDRPIGALDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVKVAARRKLEHELGIPQSQTPL-DKFLYLTRIHYLAPDGMWGEHEVDYILFITADNLNEIRDHKYVDKAELQAMFFTPWFKLIARDFLF-GWWDEL Batde5 DPEQIR-LMSEQCIVVDRNDVPIRGGSKKECHLMENID-NGLLHRAFSVFIFS-EDGRLLLQQRADEKITFPGYFTNTCCSHPLGARRAAQRKLMHEMGIEPHQVPL-DKIHFLTRIHYLAPDGLWGEHEIDYIFIFQGPNPNEVKSFRYVTKDELKTMFITPWFKLIVETFLY-KWWDNL Botbo1 DVEQSR-LMDERCIVVDENDRAIGALDKKTCHLMENIN-KGLLHRAFSAFLFRPSDGKLLLQQRASEKITFPDMWTNTCCSHPLGVRVAASRKLEHELNIPQSLTPI-DKFQYLTRIHYLAPNGLWGEHEVDYILFITADNPNEVRDVKYVNKAELQAMFFTPWFKLIARDFLF-GWWDEL Botci1 DEEQIR-LMDEVCIVLDENDKPIGNFSKKICHLMTNID-KGLLHRAFSVFLFN-SKNELLLQQRATEKITFPDMWTNTCCSHPLGVKRAAQRKLDHELGIKPAQVPI-EDFKFLTRIHYKAPDGKWGEHEIDYILFITADNMNEVRDTRYVSADGLKTMFFTPWFKLICNSLLF-EWWEHK Caeel DAQQVE-YMREQCINVDENDRIIGGVSKREAH-----SYQLVLHRAFSVFSFT-SDNKLLMQKRSAEKITFPNLWTNTCCSHPLGAKRAAIRKLEHELGI--TGVSL-NKFQMAGKYIYRAENAPWGEHELDYALILRG-NENEVAEVREVVLDELKLWMFTPWLKLFSQTETFEKWWTIN Canalb1 DEEQIR-LMEELCIVLDYDDKPVGAGTKKLCHIMDNIN-AGLLHRAFSVFLFN-EDGKLLLQQRADEKITFANMWTNTCCSHPLGAKVAAQRKLEHELGIPFEDAPI-ENFTYLTRIHYKSPSSKWGEHEIDYILILKTKNYNEVRDFKYVSADELKVMFFTPWFKLICQSFLF-KWWDNL Cangl DQEQIR-LMNENCIVLDWEDNAIGAGTKKVCHLMDNIN-RGLLHRAFSVFIFN-TEGKLLLQQRATEKITFPDLWTNTCCSHPLGAKTAASRKLEHELGIPEAETATRGKFHFLNRIHYMAPNEPWGEHEIDYILFYKIDNLNEVRDFRWVSADELKAMFFTPWFKIICDSYLF-QWWEQL Capow DAEQVR-LMEEVCILVDEDDRAVGPESKKNCHLMENIN-KGMLHRAFSVFLFN-SKGELLLQQRADEKITFPGHYTNTCCSHPLGVKRAAQRKLEQELGIKPDEVPL-DAFNYLTRIHYKAPDGKWGEHEVDYILFLQRDNPNEVKSYRYLSQDELKRLLVTPWFKLIVETFLY-KWWDQL Catan2 DPEQVR-LMQEMCILVDGNDKVIGFDTKKNTHLMTNIN-QGMLHRAFSVFLFD-ASYRLLLQQRADEKITFPGYWTNTCCSHPLGAKVAAVRKLDHELGI--TSVTK-DELKYLTRIHYLAPDEVWGEHEVDYIFVARKVSENEVKDVKYVTRDELRAMFLTPWFRLICENFLF-SWWDHL Cioin DTSQVK-LMKEECIEVDSDDNVIGPRSKLDCHLLSN---GPPLHRAFSLFLFN-SKNELLMQKRANAKITFPGYYTNTCCSHPLGVRHAAQRRLKDELGVPINQLPI-CDISFITRIHYKASSDKWGEHEIDHVLFARKDNPNEVSEVRYVSKDGMKDFTLTPWFKLILHSHLF-KWWDNI CocheC53 DEEQIR-LMDEVCIVLDNDDLPIGSATKKLCHLMENID-KGLLHRAFSVFLFD-SKNRLLLQQRATEKITFPDMWTNTCCSHPLGVRRAAVRKLNHELGIKSEQVPI-DDFKFLTRIHYKSPDGMWGEHEIDYILFMKADNPNEVRDSKWVSQEDLKTMFFTPWFKLICESMLF-EWWNHL Coere1 DEEQVR-LMGEMCIQLDQNDIPIGAVSKKQSHLMENIN-KGMLHRAFSVFLFN-SENKLLLQQRADEKITFPECWTNTCCSHPLGVKRAAQRKLEHELGIKPEQVPL-NNFKYLTRIHYLSPDGMWGEHEIDYILFIKADNVNEVKDTKYVSMDELKLFILTPWFKLIDTNFLY-KWWAQL Conco1 DDEQVR-LMEEMCILLDENDNRIGAASKKVCHLMENIN-KGMLHRAFSVFLFN-SKNELLLQQRATEKITFPDMFTNTCCSHPLGAKVAAQRKLEHELGIKPEQIPL-EKFHYLTRIHYLAPDGTWGEHEIDYIFFVKADNENEVRSIKYITPTDLKQLFITPWFKLICETFLF-KWWSVL Conpu1 DPEQSR-LMDERCILVDEQDNAIGAMDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPRSQTPV-DQFQYLTRIHYLAPNGMWGEHEVDYILFITADNENEIRDHKYVSKAELQSMFFTPWFKLIARDFLF-QWWDEL Copci DPTQSK-LMEERCILVDEEDNAIGAMDKKTCHLMENIN-QGLLHRAFSVFLFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVKVAASRKLEHELGIPLSQTPI-DQYQYLTRIHYVAPNGPWGEHEIDYILFLTADNPNEIRDHKWVSKEELRAMFFTPWFKLIARDFLF-GWWDEL Croqu1 DAAQVA-MMKERLILLDLDDNPIGVETKKICHLMSNIP-RSLLHRAFSCFLFRPSDGRLLLQKRASEKITFPDLWTNTCCSHPLGVRRAAQRKLNHELGIPASQVPL-SDFIFLTRIHYLAPDGLWGEHEIDYIFFITADNPNECSDIAWVSKSELEAMIFTPWFELIVQKFLY-PWWKLL CryneH991 DEEQVR-LMEERCILVTPEDKVYGEGSKKVCHLMSNIN-TGLLHRAFSVFLFRPADGRLLLQKRADEKITFPSMWTNTCCSHPLGVKAAAIRKLPQELGIPESQLKP-EDFHFLTRIHYLAPNGVWGEHEIDYILFSTLNNPNEVSDAKYVSKSELEDMFFTPWFKLIARDLLF-PWWDEM Crypa2 DEEQIR-LMDEVCIVLDDNDQAIGTASKKICHLMTNID-KGLLHRAFSVFLFN-DKNELLLQQRASEKITFPDMWTNTCCSHPLGVKNAAQRKLDHELGIKKEQVPL-EDFHFLTRIHYKAPDGKWGEHEIDYILFIKANNENEVQATQYVTADALKKKFFTPWFKLICNSMLF-EWWSHL Debha1 NEEQIK-LMDELCIVLDYEDKPIGAGTKKLCHIMTNID-EGLLHRAFSVFLFN-EDGKLLLQQRADEKITFPQMWTNTCCSHPLGAKVAAQRKLEHELGIPYGDAPL-ADFQYLTRIHYKSPDSKWGEHEIDYILILKTKNYNEVKDYKYVGQDELKQMFFTPWFKLICQTFLF-NWWGNL Dekbr2 DEEQIR-LMAENCIVLDYNDIPIGSGTKKLCHIMKNIE-KGLLHRAFSVFLFD-SQNRLLLQQRADEKITFPQMWTNTCCSHPLGVKSAAVRKLKHELGIEPEYVPA-SNFKFLTRIHYMSPNGGWGEHEIDYILFVKS-NPNEVKAYKYVSAEELKEMFFTPWFKLICESYLF-DWWKHI Dicdi NEIQIE-LMKEECIVVDNDDKPIRPGSKKETHLMVNIN-NGLLHRAFSIFLFN-GEGKLLLQQRALEKITFPGYWTNTVCSHPLGVKIAAKRKLNHELGVPLDQVNI-DDFTFMTKIHYKSEDPQWGEHEIDHILIMQKDEPNEVMDYKYVSQEELDQLFVTPWFRLIALNHLK-PWWNNL Dmel DPLQAH-ALKEQCILVDANDQAIGAASKADCHRVHPEN-DVKLHRAFSVFLFN-SQGEMLVQKRSSHKITFPNTYTNACCSHPLGIRVAAQRRLNYELGIPTEELQP-QDFRYLTRIHYADTDGVWGEHEIDYILFLQKDNSNEVSEVRYLRRDKIDEAVLTPWFSLILQHRLK-LWWDNL Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba DPVQAE-FMLETIVVVDNDDNPIGYDTKVNCHLVENID-KGLLHRAFSVFLFN-EKNELLLQRRASEKITFPDLWTNTCCSHMAGAKRAAQRKLVQELGITPEALPL-EDYRFLTRIHYMAPGGQWAEHEIDYILIAKRANPNEISETKYVSMDELKAILVTPWFRIICNEFLF-GWWETM Fomme1 DAEQSR-LMDERCILVDEEDHPLGAADKKTCHLMENIN-KGLLHRAFSAFVFRPSDGRLLLQQRASEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPRSQTPV-DEFQYLTRIHYLAPTGVWGEHEVDYILFITADNPNEIRDHKYVSKEELQAMFFTPWFKLIARDFLF-GWWDTL Fusgr1 DEEQIR-LMDEVCIVLDEDDKPIGTASKKICHLMTNID-KGLLHRAFSVFLFN-DKNELLLQQRATEKITFPDMWTNTCCSHPLGVKRAAQRKLEHELGIKKEQVPF-EDFHFLTRIHYKAPDGMWGEHEIDYILFIKANNKNEVRDTQYVTPESLKQQFFTPWFKLICNSMLF-EWWQNL Galma1 DPEQSR-LMDERCILVDEQDNAIGAVDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRASEKITFPNMWTNTCCSHPLGVRVAASRKLEHELGIPQSQTPV-DQFQYLTRIHYLAPDGMWGEHEVDYILFFTANNLNEIRNYKYVSKEELQAMFFTPWFKLIARDFLF-GWWDEL Ganpr1 --------MEENVIVVDPEDRPLRSGSKKETHLMSTIQ-NGLLHRAFSVFLFD-SHGRLLLQQRSDEKITFPQMWTNTCCSHPLGVKFAARRKLEHELGIPQSALEL-DQFKYLTRIHYLAPDGLWGEHEIDYVLILPYRNPNEVKAVKYVTQPELKDLFFTPWFRIIAEKFLY-KWWDRL Gloin1 ---------------------------------MENIN-KGLLHRAFSVFLFN-SENKLLLQQRANEKITFPDLWTNTCCSHPLGARRAAQRKLEHELGIKPEKVPL-DDFVFLTRIHYLAPDGLWGEHEVDYILFIRGDNKNEVKAAEFLSLDELRKKFYTPWFKLICENFLF-KWWENL Hisca1 DEEQIR-LMDEVCIVLDENDQPIGSASKKTCHLMTNIE-RGLLHRAFSVFLFD-SQKRLLLQQRASEKITFPDMWTNTCCSHPLGVRRAAQRKLDHELGIKAEQVPL-EKFDFLTRIHYKAPDGKWAEHE---------------------------------------QTNVF-D----- Klula1 DEEQIR-LMNENCIVLDWNDTAIGAGTKKLCHLMENIN-QGLLHRAFSVFLFD-SDGKLLLQQRATEKITFADLWTNTCCSHPLGARTAAVRKLEHELGIPPQEVESKGEFHFLNRIHYMAPDGAWGEHEIDYIFIYQLRSTNEVRDIAWVSQEELKQMFFTPWFKLICDNYLF-QWWNQL Lacbi2 DPEQSR-LMDERCILVDEEDNAIGAMDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPQSETPV-DEFQYLTRIHYLAPNGMWGEHEVDYILFLTANNANEIRDYKYVSKEELQDMFFTPWFKLIARDFLF-GWWDEL Lenti61 DPEQTR-LMEERCILVDEEDNALGAADKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRASEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPQSQTPV-DGFQYLTRIHYLAPNGLWGEHEVDYILFLTADNLNEIRDFKYVSKDELKAMFFTPWFKLIARDFLF-GWWDEL Malgl1 DEEQIR-LMEERCIVTDIEDRFVRDGSKKECHLMTNIR-EGLLHRAFSVFLFDPLSGKLLLQKRAQEKITFPNMWTNTCCSHPLGAKQAAQRKLEHELGIPPTCVPL-ESFQFLTRIHYLAPDGLWGEHEIDYILFITTSNENEVGDVKWVSIEELKALMFTPWFKLIVNAFLF-PWWQEL Mellp23 DAVQVA-MMEECLILVDQEDNPIGVESKKTCHLMANIP-RSLLHRAFSCFLFRPSDGKLLLQKRASEKITFPDLWTNTCCSHPLGIRRAAQRKLEHELGIQASQVPL-SDFVFLTRIHYLAPDGLWGEHEIDYIFFITAENPNECSDVAWVSQSELQDMLFTPWFKLIVDRFLF-PWWKVL Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr DEEQVK-LMAEECIVIDENDKVTGHDSKKNCHLMENIN-KDLLHRAFSVFLFS-SEGKLLLQQRADEKITFPGYWTNTCCSHPLGVRFAARRKLEHELGINPEQISL-DEFTYLTRIHYKAPDGTWGEHEIDYILFLQKDVPNEVQATRWVTQDELRELMITPWFKLIVENFIY-PWWDKL Morel2 DDEQVK-LMEEMCIVIDRDDKRIGADSKKTCHLMTNILGHNLLHRAFSVFLFSADGTKLLLQQRATEKITFPDAWTNTCCSHPLGVRTAAQRKLFHELGIEAKDVPL-DDFHFLTRIHYLAPNETWGEHEIDYILFMRPQSPNEVRDVRWVTKDELKVLLVTPWFKLICDNFMF-AWWDRM Mucci2 DEEQVR-LMEEMCIVVDENDKRVGADSKKTCHLMTNID-TGLLHRAFSVFLFD-SNNKLLLQQRATEKITFPDMWTNTCCSHPLGVRNAAQRKLEHELGIKPEQVPL-DKFKFLTRIHYLAPDGQWGEHEVDYILFIKANNPNEIRDVKYVTPEELKAMFMTPWFKLICNSFLF-KWWDQL Mydma SELQIQ-QMNEKIVLVDKNDKVLGSVSKRDSHELQ--DGNSQLHRAFSVFLFN-SKNELLLQQRSASKVTFPNYLTNTCCSHPRGVKLAAQRRLLYELGIAEEQVPI-EAMHHLTRIHYFAKNHHWAEHELDHVILIKSDNSDEVQHTQYVNQNQLRIMMATPWFRYIYEGFLF-NWWSKL Neucr2 DEEQIR-LMDEVCIVTDQNDLPIGTASKKLCHLMTNID-KGLLHRAFSVFLFN-DKNELLLQQRATEKITFPDMWTNTCCSHPLGVKNAARRKLDHELGIKQEQVPF-EDFRFLTRIHYKAPDGKWGEHEIDYILFIKANNLNEVQATQWVSAEKLKEMFFTPWFKLICESMLF-EWWASL Orpsp11 DEEQAR-LMQEMCILVDENDKVIGAESKKNCHLMENINKTNILHRAFSVFLFDKTGERLLLQQRAMEKITFPEYFTNTCCSHPLGAKNAARRKLEHELGIPPSQ----------------------------------------------------------------------------- Pench1 DEEQVR-LMDEVCIVLDNNDRPIGSASKKICHLMTNID-KGLLHRAFSVFLFD-SNKRLLLQQRATEKITFPDMWTNTCCSHPLGVKRAAQRKLNHELGIKAEQVPL-DKFEFFTRIHYKAPDGKWGEHEVDYILFIQADSPNEVRDTTYVSADELKAMFFTPWFKLICNSMLF-EWWSHL Phybl2 DEEQAR-LMEEMCIIIDKDDKPIGADSKKTCHLMDNIN-NGLLHRAFSVFLFD-SQNRLLLQQRASEKITFPDMWTNTCCSHPLGARTAAQRKLDHELGIPAHQVPL-DSFKYLTRIHYLAPDGLWGEHEIDYIFFVKADSPNEIRDIKYVTPDELRAMFMTPWFKLICNTFLF-DWWKKI Picst3 DEEQIR-LMEELCIVLDNDDKPVGAGTKKLCHIMDNIN-EGLLHRAFSVFLFN-EDGELLLQQRADEKITFPGMWTNTCCSHPLGAKVAAQRKLDHELGIPYSDSPL-ANFQYLTRIHYKSATSKWGEHEIDYILILKAKNYNEVKDYKYVSADELKVMFFTPWFKLICQTFLF-KWWSNL Plicr1 DAEQSR-LMDERCILVDEEDNAIGALDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQRRATEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPQEQTPV-DNFQYLTRIHYLAPDGMWGEHEVDYILFLTADNENEIRDHKYVDKAELQAMFFTPWFKLIARDFLF-GWWDEL Polpo DQIQID-LMKEECIVVDRDDKPLRPGSKKECHLMENIS-KGLLHRAFSIFLFN-EEGKLLLQRRALEKITFPGYWTNTVCSHPLGVRIAAQRKLKHELGVPFEQAPI-DAFTFMTKIIYVSPDAQWGEHEIDHIVVIKRKEPNEVMDYKYVSWEELQEMFLTPWFRLIAENHLE-KWWKDL Pucgr2 DQEQIA-LMEERLILLDRDDNAIGEESKKTCHLMTNIP-RSLLHRAFSCFLFRPSDGKLLLQKRAAEKITFPSLWTNTCCSHPLGVRRAAQRKLNHELGIDAAQIPV-SDFVYLTRIHYLAPDGLWGEHEIDYILFLTADNPNECSDVTWVSPNELKTMIFTPWFKLIVDRFLF-PWWNDL Punst1 DAEQSR-LMDERCILVDEQDRPIGAADKKTCHLMENIN-KGLLHRAFSAFIFRPSDGKLLLQQRASEKITFPDMWTNTCCSHPLGVKIAASRKLEHELGIPREQTPV-GNFQYLTRIHYLAPDGMWGEHEVDYILFLTADNLNEIRDFKYVDKDELKAMFFTPWFKLIARDFLF-GWWDEL Rhior3 DQEQVR-LMEEMCIVIDENDKRIGADSKKTCHLMSNIN-DGLLHRAFSVFLFD-SQNRLLLQQRASEKITFPDMWTNTCCSHPLGVRTAAQRKLEHELGIPPEQVPL-EKFKYLTRIHYVAPDGQWGEHEIDYILFMKADNPNEIRDIKYVTPQELQEMFMTPWFKLICNTFLF-KWWNQI Rhoto1 DQEQIN-LMEERLILLDNDDRAIGEGSKKDCHLIPPAETRSPLHRAFSVFLFHPQTGKLLLQRRADEKITFPKMWTNTCCSHPLGVRRAAARKLTHELGIP-HTYPL-DDFAYLTRIHYYAPDEIWAEHEIDYIFFLTLDNPNEVSDVKWVSKADLEDFFFTPWFRLIAESFLY-KWWDAL Rozal11 DPKQEEYLIREKCILVTEKDEIIGSITKKEAHHLSTPN---RLHRAFSVFLFN-ENDELLLQRRAKEKVTFPLLWTNTCCSHPLGVKAAAVRKLQHELGI--TGIKP-SDLNFLTRILYEAHDGIWGEHEVDYILFGKISNMNEVCETIFVSKDALVMISWTPWFVKIAHSFLF-EWWGDT Sacce1 DEEQIK-LMNENCIVLDWDDNAIGAGTKKVCHLMENIE-KGLLHRAFSVFIFN-EQGELLLQQRATEKITFPDLWTNTCCSHPLGAITAAVRKLDHELGIPEDETKTRGKFHFLNRIHYMAPNEPWGEHEIDYILFYKINNVNEVRDFKWVSPNDLKTMFFTPWFKIICENYLF-NWWEQL Salro DDEQVR-LMAEECILVDEDDKVLGHDSKKNCHLMENIN-KGLLHRAFSVFLFN-SEGKLLLQQRSDEKITFPGCWTNTCCSHPLGVRFAARRKLEHELGIDPSKISL-DEFKFLTRIKYLAPDGMWGEHEVDYILFLQKDVPNEVQATKWVSPNELRDLMITPWFKLIVEK---------- Schco3 DAEQSR-LMDERCILVDEEDNAIGAMDKKTCHLMENIN-KGLLHRAFSAFVFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVRVAASRKLEHELGIPQSQTPV-DEFQYLTRIHYLAPDGTWGEHEVDYILFLTADNANEIRDHKYVSKAELQAMFFTPWFKLIARDFLF-GWWDEL Schpo1 DEEQLR-LMEEVCIVVDENDVPLRYGTKKECHLMENIN-KGLLHRAFSMFIFD-EQNRLLLQQRAEEKITFPSLWTNTCCSHPLGVKNAAQRKLFHELGIQAKYIPK-DKFQFLTRIHYLAPTGAWGEHEIDYILFFKGKNPNEVQAYKYVTMEELKEMFFTPWFKLICEHFMF-KWWQDV Sorma DEEQIR-LMDEVCIVTDENDLPIGTASKKLCHLMTNID-KGLLHRAFSVFLFN-DKNELLLQQRATEKITFPDMWTNTCCSHPLGVKNAARRKLDHELGIKQEQVPF-EDFRFLTRIHYKAPNGKWGEHEIDYILFIKANNLNEVQATQWVSAEKLKEMFFTPWFKLICESMLF-EWWASL Sphar DDEQVR-LMAEMCIEIDTDDNAIGSVSKKEAHLMPNIN-KGLLHRAFSVFLFN-TEGKLLLQQRATEKITFPDCWTNTCCSHPLGAKNAAVRKLDHELGI--TGVTT-DQLEFLTRIQYMAPDGMWGEHEIDYILFAQCDNENEVRAYKYVTQDELKDLFITPWFKLICETLLY-KWWDNL Spipu1 DREQVR-LMGEMCIVVDENDKALKGDSKENCHLMRNIN-EGLLHRAFSVFIFN-KEGKLLLQQRADEKITFPGYFTNTCCSHPLGARRAAQRKLEHELGIPPEQVPL-DKLEFLTRIHYLAPDGLWGEHEIDYIFIFKGENPNEVKSIKYVSKEELQEIFLTPWFRLIVEKFLY-TWWDNL Sporo1 DQEQIN-LMEERLIMLDNDDKAIGEGSKKDCHLIPPE--RSPLHRAFSVFLFDPESGKLLLQRRADEKITFPKMWTNTCCSHPLGVRRAAARKLEHELGIP-KTYSL-EDFSYLTRIHYYAKDDIWAEHEIDYILFLTLSNPNEVSATKWLSKAELVEFFFTPWFKLIAESFLY-KWWDAL Stehi1 DAEQSK-LMEERCILVDPQDNAIGAADKKTCHLMENIN-KGLLHRAFSALVFRPSDGKLLLQQRATEKITFPDMWTNTCCSHPLGVRIAASRKLEHELGIPRSQTPV-DKFQYLTKIHYLAPDGLWGEHEVDYILFLTADNLNEIRDWKYVDKAELQAMFFTPWFKLIARDFLF-GWWDEL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr DEVQKE-LMAEECILLDEADNVVGKESKKTCHLNTVIEEKGLLHRAFSVFLFN-SEGKLLLQQRADEKITFPGYWTNTCCSHPLGVKRAAIRKLEHELGIPAEEVPL-EAFHWLTRLHYKAADGLWGEHEIDYILMCQLDVANEVKDIRYVSKDELVELLITPWFRLVVDNFLLPKWWDQL Treme1 DEEQVR-LMEERCILVDPQDKAYGEGTKKACHLMSNIS-SGLLHRAFSVFLFRPSDGRLLLQRRAAEKITFPDMWTNTCCSHPLGVRAAAIRKLPHELGIPPEQLHP-DDFTFLTRIHYLAPDGLWGEHEIDYILFSALDNYNEVSDATYVSREELEAMFFTPWFRLIARDLLF-PWWDDM Trire2 DEEQIR-LMDEVCIVTDENDAPIGTASKKICHLMTNID-KGLLHRAFSVFLFN-DKNELLLQQRASEKITFPDMWTNTCCSHPLGAKRAAQRKLEHELGIKPEQVPF-EDFHFLTRIHYKAPDGKWGEHEIDYILFIKANNPNEVQATQYVTADGLKKLFFTPWFKLICNSMLF-EWWGSL Umbra1 DEEQVR-LMEEMCIVIDKDDKRIGAESKKTCHLMDNIN-TGLLHRAFSVFLFD-SQNRLLLQQRASEKITFPDMWTNTCCSHPLGARTAAQRKLDHELGIKPEQVPL-DDFEFLTRIHYLAPDGMWGEHEIDYIFFIRADNLNEVRDTKYVTPEELRAMFMTPWFKLICETFLF-KWWANI Ustma22 DEEQIR-LMEERCIVLDNDDKYVRDGSKKECHLMTNIN-KGLLHRAFSVFLFDPTTGKLLLQRRALEKITFPNMWTNTCCSHPLGVRRAAQRKLDHELGIRAEQVPL-DEFQYLTRIHYLAPNNMWGEHEIDYILFITADNLNEVCDTKWVSPEELKALMFTPWFKLIVHKFLF-PWWSEL Walse1 DLEQIR-LMEERCILLDENDNVMGDVSKKDCHLMDNIN-KGMLHRAFSTFLFRPSDGRLLLQKRSKEKITFPDLWTNTCCSHPLGAKNAAIRKLEHELGI--KGLKP-DQFDYLTRIHYLAPDSLWGEHEIDYILFIKADNPNEISESRYVNQQELKDMMLTPWFELIGDELLF-KWWDQL Zygro1 DEEQIK-LMNENCIVLDWNDEAVGAGTKKLCHLMKNIE-KGLLHRAFSIFIFN-EQGELLLQQRASEKITFPDLWTNTCCSHPLGARTAAIRKLDQELGIPQQQTKEHGQFHFLNRIHYMAPNEPWGEHEIDYIFFYKLNNLNEVQDYKWVNKNTLQEMFFTPWFKLICESYLF-EWWGKL [Cluster2008.fasta_al_trimmed; alignment length = 179] Allma1 YVVPGD-RVLRLGPGLIVAVKAGMLWI-VTDQKRYVPAAGDDVVGVITNKLAEAYKVDIGS-AHPAVLSYMAFEGASKRNRPTHNVGDLVYARVAMKDMD-PEIECVNPKSLKAN--GYGLLA-GGFVIK-TSLAFARSM-LD-PNVHKALEKHFFETAVGQNGRIWIMLTIAI-ADAL Ashgo11 ----------------------------------------------------------------------MAFPNASKKNRPTLKVGDLCYARVAEKDLE-AVLECMDSSTGRDA--GFGQLD-GGMVAE-VSLGFAREL-LLNEALLPEMARHAFEVAIGVNGKIWVRTTLCC-IRAI Aspfu1 ILLPGD-HVLRLGPGLIASTQAGLLSVLSFPNRRYIPTPNDLVIAQVHHSSAEYFYCMITPQSPHVLLGQLAFEGATKKTRPMLRQGDLVYARVLGAGAE-VELTCVNPATGKAEPGGLGPLN-GGMVFD-VSTGMAARL-MR-ASVLEELGRKLFEIAVGRNGKVWVKATVAI-GRCL Aurde31 FVLPGD-NVLKLGPGLIIATKAGTLWV-ESNARRYVPAAQEGVIGVVAHKAGEGYRVDIGG-AHYASLDGLAFEGASKRNRPMLKVGTLVYARIAHKDME-PELQCYDAQTRKSE--GFGELK-GGFMQP-CSLGTSRAL-LD-PALLPMLGARFLEVAVGVNGRVWFRQTIAV-SRCI Batde5 FVLPGDIVVLRLGPGLIVAIKSGFVWL-TASQKKYIPALGEPVLAVVSSKHMESYRVDIGG-PHPAALPVLAFEGATKRNKPNLEVGALVYARVANKDME-PEIECINPSSGKAD--GFGELN-DGFMIK-CSLGMCRSL-MA-KNILAQISSLFFETAIGMNGRVWIKQIIMI-ANLI Botbo1 -----------------IATRPGVLWL-ESNAKRYVPAPQESVIGIITNKHAEGYRVDIGG-AHNASLDALAFEGATKRNKPNLKIGSIVYARVAHKDME-PELECFDAQTRKAG--GFGELR-AGFLVN-CSLGTCRAL-LD-PKLIPLFGARFLEIVTGMNGRVWVRHTIAL-ARCI Botci1 -VLPGD-HILKLGPGLITSTVAGQLWV-EFNAGRYIPTVGDLVIASIKKSAGDVFYANLSDFTSDASLPVLSFEGATKKTRPQLEKGALVYARVANKHMD-PELECVSASTGKSE--GLGPLE-GGMLFD-VSLGMARRM-MM-ARILEELG---FEIAVGRNGKVWVKTTLAI-GKAL Caeel VYLPGD-VISIIGYGIRIATQPGAFWL-NVHSKRYIPQEGDRVIAIVTSKTGDFFRLDIGT-AEYAMINFTNFEGATKRNRPNLKTGDIIYATVTTPRTE-AELTCVD-DEKRAR--GMGQLN-GGFMFK-VSLNHCRRL-IN-PSILQTVGKFFFEITVGMNGRIWIDDIIKI-HDII Canalb1 IILPGD-KLTTIGPGILIPSAAGTLYI-ESNSKRYIPHTNDYVIGIITGAIGESYKVSLQSNSTPVLLSFWAFPNASKKNRPNLKNGQAVYARVDIPEIE-TELECIDPTSGKEG--GFGVLDESGYIFD-VHLNFAREL-LFNPKFLETLATRCFEIAIGINGKIWIKSTLAA-ATFL Cangl VVMPGD-ELVVLGPGVVVPVNAGVPYV-EYNSKRYIPSVGDLVIGVITSTFSDSYRVSLSSFSNSVSLSYMAFPNASKKNRPTLKVGDLVYARVAEKELE-AEIECLDSTTGESA--GFGLLE-GGMVID-VTLAFARRL-LFNDNLLLLLSKRTFEVAIGVNGKVWIKYTMAC-FRSI Capow VVLPGD-ALLRLGPGLIAASRAGVLYI-ASSQKRYVPAKDELVVGIITDRMGEAFKVDIGA-AASASLSFLAFEGATKRNRPNLAIGALVYGKLANKDME-PEMVCIDA-ADKAA--GMGELT-GGYLIH-ISSGLTRRL-LS-RDVLIALGKHFLETAIGLNGRTWIQQVVLI-ANAI Catan2 FVFPGD-AVVILGPGVVVATKAGMLWI-DSDQKRYTPSANENVIGVVTHRLAEMFRVDIGT-AHPAVLSAMAFEGASKRNRPNCNVGDLVYARIASKDMD-PELECVNPRTGKSS--GYGVLK-GGFVAK-VSLKTCRGL-MY-TNTAKILGKYFFEQAVGQNGRVWIVMSVRI-ARAL Cioin IVIPGD-VIVKLGPGLVKVCKPGVLWV-DCHQKRYVPSKGDNVVGVVTSRQGDMYKVDIGA-SHLAVLNYMSFEGASKRNRPNVTNGDLIFGKLANKDME-PEVSCVDPNNGKAN--GLGVLS-DGFSFH-VPLNLARKL-LS-PSLIHELGARIFEITVGMNGRIFLKFVILI-MDVI CocheC53 -VLPGD-EILTIGPGLVTATIAGALSI-EFNSGRYLPYTGDLVIATVSSSAAETFNCLLTPSTPPATLPHLAFEGATKKTRPQLPPNSLVYCRVAGKDLP-PELTCVDPSTGKSE--GLGLLK-GGMVFK-VSLGMARRM-LA-ARLLETLG---FEVTVGRNGLVHVRATLAI-GKAI Coere1 VVIPGD-IILRLGPGLISASAAGVLWV-VSNRRRYVAAEGEPVVGVVVGRHGEGYRVDIGS-AQDALLPLLAFEGATRRNKPNLTIGAVVYARVANSVMD-PEIECYNSNTGKSE--GYGELT-GGFMFK-CSLGLARHL-IS-AKVLNALGAQIFETAVGVNGRVWVETTVLV-VNAI Conco1 KSLPGD-ILLKLGPGVLVAINAGELWL-EFDSKRYKPSVHDPVIGKIVGRQTDHYLVDVGC-AFPAMLPHLAFEGATKNNKPNLNVGDLVYGRMCHKDMD-PEMECYNSDTQKSQ--GFGPIV-GGTLVR-GSLGWSRSF-LNNPKILNTIGQQLFEVAIGVNGKIWIQNTLAI-KRIL Conpu1 AILPGE-LVLKLGPGLILATRAGALWV-ESNARRYVPAAQESVIGVVTARGGEAFRVDIGS-AHHANLDGLAFEGATKRNRPNLKVGTLVYARVAHKDME-PELECFDAQTHKSD--GFGELK-GGLAVT-CSLKMCRML-LD-PSLLPFLGARFLDAAVGVNGRVWIQTTIVA-TRLI Copci VVLPGE-QVLKLGPGLVISTKAGVLWV-EGNSRRYVPAPQESVIGVVTQRLGEGYRVDIGS-AHQASLDALAFEGATKRNKPNLKVGSLIYARVAHKDME-PELECFDAQTRKAE--GFGELK-GGFMIK-CSLKLCRDL-LD-PRLFPLLGARFLESAIGMNGRVWIKHTIAI-ARCI Croqu1 VVLPGD-LILTLGPGL--VTRAGLLWV-EGNGKRYVPALGEPVIGIIISRQADGYKVDIGS-SLTARLDAFAFESATKRSKPNLKVGTVVYGRIALPFIE-PELECVDPTTMKAN--GFGEMS-GGYLIRDLDLRHSRSL-LS-PPLLAKLGQQIYEISIGLNGRIWLTHTIYLVNQIT CryneH991 LILPGE-TVVMLGPGIYIATRLGMLWI-EGNSKRYIPAQKDIVLGIIIARHADGYRVDLGS-SQMAQLDALAFEGATKRSKPNLKVGTLVFARVASRDME-PELECFDPNTGKSD--GFGELK-GG-VMVNATLQLCRRL-LD-RNVLPTIASVFFEIAIGLNGRVWMGETLAM-KRLI Crypa2 -VLPGD-ALLQLGPGLILPTVAGQLWV-EYNGGRYVPSQGDLVIGQVHHGAADFYYVQLTPHTSNALLPVLAFEMATKKTRPQLAPGQLVYARVANKHMD-AELECVNPATGKSD--GLGPLN-GGMLFS-VSLGFARRL-LM-PKVLEELG---FEIAVGRNGRVWVRSILIV-GRAL Debha1 IVIPGD-GITTIGPGIIIPASAGILFT-DSNSKRYIPQTNDFVIGIIVGVFGESYKVQLQDFSTSVQLSMMAFPNASKKNRPNLKIGQAVYARVAIPEID-TELECIDPITGKEG--GFGLLDESGYIFN-INLNFAREL-LFNQSFLEKLSTKCFEIAIGINGKVWLRATLAA-CRFL Dekbr2 VVIPGD-HIITLGPHILNPTTVGLLYV-EANSKRYLPESGDNVIGVIIGSFGDFYRVSLNDFSVPVVLNQFSFPNASKKNRPRLEVGDLIYARVVNPNVD-AEISCVDPTTGKAE--GYGKLE-GGMVFK-VKLAYARNL-LFDPNILTELVTKCFEIAIGVNGKIWLLSTIAC-GRCI Dicdi FVVPGD-VIVRIGPGLVLATKAGVLWI-ENEQKRYVPQVEDMVIGTIIEKHAESFKVDIGS-SCSALLSAYSFEGATKSNKPLLNVGNLIYCRVANRDME-PEVVCLSQK-QKAE--GFGQLI-GGYMLN-CSLGLSHYL-LS-EDLLQILGKHIYEIAVGVNGRVWIHNTIVV-SNTI Dmel IVMPGE-RIVILGPGLVVASKAGPLWV-DNYQRRYIPARGDLILGIVRAKAGDLYRVDIGA-TDTASISYLAFEAASKKNRPDLIPGDLIYARVASADIE-PELVCVN-SVGKSG--KLGVLT-DGFFFK-CSLNLGRML-LR-ENVLAALTRELYEIAVGVNGRIWLKETVAL-ANAI Enthi TVFPGD-TFARFGDGIPTVSRAGILHV-FSDLKKYHPSVEDVCVGKIVKRVKDKYLVDIGS-YCYAELDFLAFENATKKSKPNLLDGDYVYCRVVSKENV-PQVVCV--SQRKME-DGFGELQ-GGWAFS-VPQSMCRRI-MG-DGVLTCIGEYTFEIAVGINGMVWVLNDVIV-ESCI Falba VVLPGD-TLLTLGPGVIVSSRAGVAWV-ESHSRRYLPAENESVIGVIVDRAGETYRVDIGA-PTLASLPLMAFEGATKKVHPDLKPGAVIYTRIAYRDLDPPELDC-----RQAD--GLGGHY-GIYCFN-VPIAAARRLRAPCPAVLDIMRTHFFEDCVGDNGVVWIYRAVALLAEAI Fomme1 TTLPGE-LVLKLGPGLIISTRAGALWV-ESNSRRYVPAPQEYVVGTVIAKAGEGWRIDIGG-AHMASLDGYAFEGATKRNKPNFKINSLIYARVAHKDME-PELECFDAQTRKSE--GFGELK-GGFLVR-CSLGMCRSL-LD-PKLLPLLGSMFLETAVGMNGRVWIKHTVAV-ARCI Fusgr1 -VLPGD-SILRLGPGLIIPTLAGQLRV-ENARGRYTPRVGELVIGTIQRSAADFFFVTLSDYTAPAQLPQLSFEGATKKTRPQLAAGALVYARVANRHMD-PEIECVSASTGKSE--GLGPLA-GGMLYN-VSLGMARRL-MM-PKVLEELG---FETATGRNGKFWVKTVIAV-GRAV Galma1 IVFPGD-HVLKLGPGIIIATRAGDLWV-ESNSRRYVPAPQEQVIGSIIQKVGEGYRVDIGS-AHFASLDGLAFEGATKRNKPSLKVGSLVYARVAHKDME-PELECFDAQTRKSE--GFGELK-GGFIVR-CSLKMCRDL-LD-PKLLPLLGARFLEAAVGVNGRVWVKQTIAI-VRCI Ganpr1 PVIPGD-TVVRIGPGLVVVVKAGVLWV-ESNFKRYVPVQGDPVVGQITYKSADFFRVEIGA-AHQAQLSALAFEGATKRNRPPLEVGSLVYARVAHRDME-PELECVDQTTGRAE--GFGELK-GGFMIK-CSLGMARNL-LL-PKLLPTLGTRFFETAVGVNGRVWIPRIAAV-ARCV Gloin1 VVLPGD---LKLGPGLVICIKAGILYV-ENNQRRYIPAERDPVIGIVTYKGGEYYRLDIGS-AHQAILPILAFENVSKKSRPNLNIGSLIYAKVANKDME-PEVWCYNPDTNKAE--GFGELK-NGYVIK-CSLRYCRRI-IS-QELLKKLGEKFFEIAAGMNGRIWIKNTIYC-CNVI Hisca1 LLLPGD-PITKLSSGLITATQAGLLTLHTFPQRRYIPSPNDFLIAQIHHSSVDYFHCNITPHTPYALLGQLAFEGATRKTRPLLKHGDLVYARVVGNAGE-VELTCVNPATGKAEPGGLGPLA-GGMVFD-ISTGLAERLSLR-GGVLEELGSRLFEIAVGRNGKVWVKTIVAV-GRCL Klula1 LLLPGD-VIISAGPGIIKATHAGLEYV-DYNSKRYIPAVGDFVVGVIVASFGDSYRVSLCNFSNPVTLSYMAFPNASKKNKPTLKVGDLCYARVAYKELE-AEIECMDSSKGQDA--GFGLLD-GGMTIE-VSLAYAREL-LFNDSLLNILGNLVFEVAIGVNGIIWLRTTLAC-YRSI Lacbi2 VVLPGE-EVLKLGPGLIISTRAGILWV-ESNSKRYVPAPQESVVGVITQRLGEGYRVDIGA-AHYASLDSLAFEGASKRNKPNLKVGCLVYARVAHKDME-PELECFDAQTRKSE--GFGELK-GGFVVR-CGLKMCLDL-LD-TKLLPLLGGRFLEVAVGLNGRVWVKQVIAI-VRCI Lenti61 SVLPGE-NVLKLGPGLIVSTRAGEVWI-EGNSRRYSPAPQESVVGVVVSRSGENWRVDIGS-AHMATLDGLAFEGATKRNRPNLKVGSLLYARVAHKDME-PELECFDAQTRKSE--GFGELK-GGFLVQ-CSLKMCRLL-LD-PQLFPLLGSRFLESAIGMNGRVWVRQVIAI-ARCI Malgl1 VVLPGD-VIIKLGPGVLTSIHTGALYV-ESAQRRYVPSVGDRVIAQVTNRGMESYTLTLFS-AHPSTLPVLAFEGATRRNRPNLQIGALVYARVAEPWSE-PELSCIDPIHNKAD--GMGELK-AAMVWQ-VSLSLAQSM-LR-PQLLLNVSKHFFEAAIGKNGLVWVEHAIAL-GRVL Mellp23 ----------------------------------YVPALGEPVIGIIVSRQADGYKVDIGS-SLTARLDALAFESATKRSKPNLKIGTVVYARVALPFIE-PELECMDPTTMKAN--GFGEMT-GGYLMRDLDLRNSRLL-LS-PPLLAKLGQQVYEISIGLNGRIWLSQTIYL----- Mnele IVVCGD-SFLTVGPGLVTCTKPGVIWI-DRNNRRYVPVLEERVIGIIIGRVMDEYRVDIGG-AHVAMMSTIAFEGATQRNKPELKPGNVVFARVANKDVE-PELACVN-KKGKAN--GLQVLE-GGHIIQ-CSLGLSRKL-RQ-HKLTQPLFNHFFELCVGMNGRVWVKHTVAI-SIYL Monbr VVVPGD-RFVVLGPGLGVVTHGGILWV-DIATHNPQTAEGDQVLGIIIGNAGEGFLVDIGG-ASNALLPGLAFEGATRRNRPRLNPGDLVLARLANRDMD-PELTCVT-SGGKSA--GMGHLE-GGLLRE-ISLGLCRRL-RG-KNVLTELGSR-FELCVGMNGRMWLMDAVLL-ANAI Morel2 IVLPGD-QLLTLGPGLITAVKAGILWV-ESNQRRYVAAQGESIIGVVTGKSAEHYKVDIGA-SQPALLGVLAFEGATKRNKPNHNIGDLLYCRVANKDME-AELECMNPTTGKAD--GFGELK-GGFVIK-ISLGLARRL-LD-PKVLRLLGQHIFEMAVGTNGKVWVQHTILI-CNAI Mucci2 IVLPGD-VIIVLGPGLIVAMKAGILWI-ESNQKRYIAATGESVVGTVIAKMGEYFRVDIGT-AHSAVLPMMAFEGATKRNKPNLNVQSLVYCRVANPDME-PELECVNPRTGKAD--GFGELV-GGFVIK-CSLGLCRRL-LN-PNILSYLGEHFFETAVGMNGRVWIKNTILI-SNAI Mydma VFLPGD-TILKFGPGLVVAFKAGILWI-DTNQKRYVAVKGDTVIGIITTRGADSYKVDIGS-SQPAYLNNLLFEGATKRNKPNLKINDLVFAKLANKDME-PEISCID-ENNKSN--NLGPLN-DGYMFT-VSLGLSRKL-LQLPMVLSLLGKNFFEIVVGLNGRIWIIDTIAI-ANAI Neucr2 VVLPGE-TILRLGPGLIVPTVAGQLWI-EYNGGRYIPSQGDLIIGQIARSATDFYYVSLSPYTPNATLPHLAFESATKKTRPQLASGELVYARVANRHMD-PELECVNSSTGKAD--GLGPLK-DGMVFD-VSLGFARRL-LM-AKVLEALG---FETAVGRNGKVWVKTAVMV-GRAL Orpsp11 ----------------------------------------------------------IGA---------------------------LVYARVANKDME-PELECISASTGKAN--GFGELK-NGFLIK-CSLGLCRSL-LN-PNILTALGEHFFETAVGMNGRVWISNTILL-SNAI Pench1 VLLPSD-EVLRLGPGLLTATQAGLLSLLSFPNRRYIPTVNDFVIAQIHHSSVDFFHCMVTPHTAHALLGQLSFEGASKKTRPMLKQGELVYARVVGAGAE-VELTCVNPATGKAD-GGLGPLT-GGMVFD-VSTGMAARL-IR-ASVLSELGKKLFEIAVGRNGKVWVKVTVAV-GRCL Phybl2 VVLPGD-IIIILGPGLIVAVKAGILWI-ESNQKRYIAAAGDSVLGTVTARLAEFYRVDIGT-AHSAVLPVLAFEGATKRNRPNLVNRSLVYCRVANPDME-AELECVNPTTGKAD--GFGEMK-GGHVFT-CSLGLCRRL-LN-PEVLKLLGDEMFELAVGMNGRVWVKDTITV-CNAI Picst3 LIIPGD-FLTTIGPGIILPTNAGLIYI-ESNSKRYTPQTNDFVIGIVTGVIGESYKVQLQDFSPAVLLSMMAFPNATKKNRPNLKIGQAVYARVAIPEIE-TELECIDPTTGKEG--GFGLLDESGYIFE-VNLNFAREL-LFNANFLEKLASKCFEIAVGINGKVWIKSTLAA-AGFL Plicr1 IVLPGE-HILKLGPGLIISTRAGTLWI-DSNSRRYVPAAQESVVGQVVGRSGEGYRVDIGS-AHSASLDGLAFEGASKRNKPNLKVGSLVYARVAHKDME-PELECFDAQTRKSE--GFGELK-GGFIVR-CSLKTSRLL-LD-PKLLPMLGARFLEAAVGTNGRVWVRHTIAI-TRCI Polpo FVLPGD-CIVRIGPGLVIASKCGVLWI-ENEQKRFVPQVEDMVIGIIVDKHPESFKVDIGS-SSLALLSAYSFEGATKNNKPLLQVGNLVYCRVANKDME-PELVCMSVR-NKAE--GYGQLV-NGYMFN-CSLGLSHYL-LS-EDILKILGKHIYEIAVGVNGRVWVQQTIIV-ANTI Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 TVLPGE-HVLKLGPGLIMSTRAGALWI-DSNSRRYVPAPQESVVGVVIARSGENWRVDIGS-AHMATLDGLAFEGATKRNRPNLKVGSLVYARVAHKDME-PELECFDAQTRKAE--GFGELK-GGFLVK-CSLKMARLL-LD-PSLLPFLGQRFLEVATGVNGRVWIKQTIAV-SRCI Rhior3 IVLPGD-AIVILGPGLVVATKAGILWI-ESNQKRYVASTGESVIGTVIAKLGEYFRVDIGT-AHAAVLPMLAFEGATKRNRPNLSVRSLVYCRVANRDME-AELECVNPTTGKGD--GFGELV-GGYVFT-GSLGLCRRL-LN-PNILTLLGEHFFETAVGMNGRIWVNITILI-ANAI Rhoto1 VALPGD-PLLHLGPGLPAATRAGLLWI-EGTMKRYTPNPPEPVLGIIVARHAEGYRVDIGS-SQGASLDALAFEGATKRNKPNLKVGTLVYAHLTPPFSE-PEISCVDPSTQKAS--GFGELQ-GGFLIRGVELGRCRAL-LA-PKVLSKLGARFFEVAVGMNGRVWV----------- Rozal11 IALPGD---KKIGPGLIISTKPGILWL-ESSQKRYIPSLNDPVVGIVTAKLTDFYRVDIGS-HQLAILPNLAFESATKRNRPNLNVGSVVYARVANKDLE-PEISCMSI-LNKSD--GFGELS-DGFIVH-CSTGLCKRT-LK-PDILEGVGSNFFECATGLNGRIWIKETIQL-SMVL Sacce1 FIFPGD-SFVKLGPGIIRPVNTGVLYI-DYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQNFSSSVSLSYMAFPNASKKNRPTLQVGDLVYARVAEKELE-AEIECFDSTTGRDA--GFGILE-DGMIID-VNFNFARQL-LFNNDLLKVLAAHTFEVAIGLNGKIWVSNTLAC-YRTI Salro FVAPGD-TVLRIGPGLTQLRAAGVLWV-DGVHKRALPAEGDYVIGIITGTPGENYNVDIGG-SCNAT---------------------------------------------------------------------------------------------------------------- Schco3 AVLPGE-QVLKLGPGLIVATKAGTVWV-DANSRRYVPAAQESVLGVVTLRVGEAFRVDIGA-AHNANLDGLAFEGATKRNRPQLKVGSLVYARVAHRDMD-PELECFDAQTRKAE--GFGELK-GGFLVH-CSLLMCRQL-LS-PDLLPLLGSMFLEAAVGMNGRVWIKQVIAM-KRCI Schpo1 YYFPGE-RIIRLGPGLIVVSKAGRLLI-DSRTKRYIPATNDQVIGQIISRFAEGYRVDIGS-AHIAQLNALAFENVTRKSRPNLNVGSLVYARVADRDME-PELECFDATTGKAA--GYGELK-NGYMITGLSLSHCRKL-IL-PKLLQTLGSYIFEIAVGMNGRVWVSTTVLICTAIR Sorma VVLPGE-AILRLGPGLIVPTVAGQLWI-EYNGGRYIPSQGDLIIGQIARSATDFYYVSLSPYTPNATLPHLAFESATKKTRPQFASGELVYARVANRHMD-PELECVNSSTGKAD--GLGPLK-DGMVFD-VSLGFARRL-LM-AKVLEALG---FETAVGRNGKVWVKTTVAV-GRAL Sphar VVIPGD-VVLTVGPGLIVAEKAGILYI-DSSQRRYLPVKDDRVIGAVLNNGRDAFQVDIRS-AQLASLPYLSFEGVTKKNRPDFKTGDLVYTRVANKDME-PELSCVN-GQEKAD--GMGILT-GGFSFQ-TSLGLCHRL-LR-PKLVTALGEHFYEMTVGLNGIVWVEQTIIA-ANAT Spipu1 LVIPGD-HIVRVGPGLLVAVKAGILWV-EGTQKRYVPALGESVLGIIASKHGEFYRVDIGA-AHPASLPVLAFEGATKRNRPNLEVGSLIYARVANKDME-PELDCIDPATGKAG--GFGELK-DGFMVR-CSLGMARRL-LD-PRILLRLAEAFFETAVGMNGRVWVPHIITV-ARAI Sporo1 --------------------------I-ESHQYRYTPSPPEPVLGIVTARHAEGYRVDIGA-SQPASLDGLAFEGATKRNKPNLKIGTLVYGYLTPPFAE-PELSCVDQTTQKSA--GFGQLD-DGYLIRGVELGRCRAL-LS-PKVLSQLGSKFFEVAVGMNGRIWVSSSLTT-GAAG Stehi1 IVLPGE-TVLKLGPGLVVSTRAGELWV-ESNARRYVPAPQESVVGVVTGRMGEGFRVDIGG-AHNASLDALAFEGASRRNRPALKVGSVVYARVAHKDME-PELECFDAQTRKAE--GFGELK-GGFLTR-CSLKMCRQL-LD-PDLLPMLGSRFLDAAVGVNGRVWVKQTIAV-TRCI Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr VVSPGQ-VVLRLGFGLVKATKAGVLWV-DAAQKRYVPAREDAVVGVVTARRGENYDVDLGS-AFPAALSLLAFEGATKRNRPQLEVGDLVYARVADKDMD-PELECVDAK-GKSA--GYGPLA-DGYVVN-TSLSLVRRL-FN-PKVLAALGARLFEVALGLNGRVWILHTIVI-ANAI Treme1 IVLPGD-RLVTLGPGIFIATKLGVLWV-ETRSKRYIPAQKDLIIGTIIARHAEGYRVDIGS-AQMAQLDALAFESATKRSKPNLKIGTLVYGRVANRDMD-PEIECFDPSTGKSE--GFGELK-EG-LMVECSLQLCRQL-LK-PKLLLALASQVFEIAIGLNGRIWLGETIAL-KRVI Trire2 -VLPGD-RILRLGPGLLVPTLAGQLRV-ETANGRYIPRVGELVIGTVNKSAQEVYFVSLSDYTAPALLPQLSFESATKKTRPILLPGALVYAR------------CVSASTGKAD--GLGPLV-GGMLFT-ISLGMSRLL-MM-PKVLDELA---FETATGRNGRLWVKAIIAV-GRAI Umbra1 VVLPGD-LIVRLGPGLIVSMKAGVLWL-ESNQRRYVAATGESIIGIVVARLAEYYRVDIGA-AQSAILPILAFEGATKKNKPNLIPGTLVYARVANKDME-AELQCFNPSTGKAD--GYGELK-GGFVIK-CSLGLCRRL-LN-PEILSFLGEHFFETAVGMNGRIWVKYTILL-ANAI Ustma22 IVLPGD-VVIKLGPGILSAIRAGALWV-ETNTTRYVASASDSVIGQITNRGAESYTVSLFG-AHSATLPALSFQGATKRHKPNLRIGSLVYARVADRFTE-PELTCVNPVTGKSD--GFGHLK-TAMLVR-CSVGLAKSL-LR-PTLLKQIATHFFEAAVGANGAVWIKHVIAV-SKVL Walse1 ---------------------------------QYLARTGDSVIGQVIFRGSEGYRVDIGT-ATTANLDALAFEGATKRNKPNLKVGSLVYARIAHKDME-TELECLNPTTGKAE--GYGELK-GGILADNLDINKCKSL-LE-KNFMNTLMQGFFELATAMNGKIWISQTISV-YRTI Zygro1 VVFPGD-QLLNIGPGVVLPINAGSAYI-DYDSKRYIPAVGDLVVGIIVGQYTDSYKVSLSSFSTSVTLPYMAFPNASKKNKPTLKIGDLVYARVAEKELE-AELECVDATTGKDA--GYGLLD-GGMTVD-VTLKFARHL-LFDNSLLPILAKHTFEIAIGVNGKIWIKDTLAC-YRSI [Cluster2018.fasta_al_trimmed; alignment length = 103] Allma1 PLFVTWLRGCIGNFSRLHSGLREYALISALQDRRFAPILQCGVSLLLAFELDWDV-GVHGVRISATYLPEVALAQEWDHVAAIDSLVR-KAGYQGVTRYQSSK Ashgo11 SVFITWLRGCIGTFAPLLRGIEKYSLIAALQDSRFPPILKCSCNVLSHFKYDWKV-GRHGVILSATFLPEVMVEQGWSQLETFENLIE-KAGCWQVITYRGDK Aspfu1 PLFVTWLRGCIGTFDELAEGLRAYALTSAFEDSRFTPILSCSLTLLGSFELDWIL-GVHGIRIGATYLPDVAVEQGWTKEETLESLMR-KAGWDGVVKYQGLK Aurde31 PLFVTWLRGCIGSFETLHAGLAEYALISAFRDSRFRRILQCGVSLLVEFELDWSV-GVHGILISATYLPDVMPEQGWTKQEAIDSAIR-KAGWDGLRRYQSSK Batde5 PLFVTWLRGCIGNFSPLHKGLEEYAIVSALQDTRFNPILSCGVSLLINFEQDWEI-GKHGIRISATYLPEVASEQGWDHKQTIDSLLR-KGGFRGLVRYQSSK Botbo1 PLFVTWLRGCIGTFESLREGLAEYALISAFKDRRFTPILECGISLLTDFELDWTV-GKHGIYINATYLPEIAPAQGWSKVEAVDSAIR-KAGWEGLRRYQSRK Botci1 PLFVTWLRGCIGTFSPLLSSLPEYALISALHDSRFDPILEVAVTLLTDFELDWDI-GVHGIRIGACYLPDVAVEQDWGKEETVVSAMR-KAGWGGVVRYQGRK Caeel PLFVTWLRGCIGTFSRLGEGLNEYAKTSAFHDSRFKPILQCGVSLLINFERDWTI-GRHGVRMSAVFLPEVAQEQGWNHVETIDHLIR-KSGYGGIVRFQSSK Canalb1 PLFITWLRGCIGTFSPIESGVSRYALHAALQDPRFFPILEVSVTLLDNFVLDWEI-GVNGLKISGTFLPSVAEEENWDKLTTLHYLLK-KADY-PLTRYDGLK Cangl SLFITWLRGCIGTFAPIEAGIQRYSLIAALEDSRFTPILKCSCNILRHFEDNWEI-GKNGIELSATFLPDVMVEQGWDKKETFLNLIQ-KAGCWNVIKYEGKK Capow PLFVTWLRGCIGTFSPLHDGLAEFSLRSALKDRRFSPILTCGVSLLINFELDWEI-GVHGIWITATYLPEVMPEQGWTKIEAIDSLLR-KGGYRALTRYQSVK Catan2 PLFITWLRGCIGNFSPLPAGLRDYALISATQDHRFAPILHVAVSLLVDFEFDWTI-GTHGIRIGATFLPEVAKDQMWDHKRTLVQLVK-KAGYVGVVRYQSSK Cioin PLFVTWLRGCIGTFSSLHSGLREYAITSSMKDNRFSPVLSCSVSLLTNFEYDWKV-GIHGIRITATYLPEVSKEQGWNEQQTVENLLR-KGGYRSTKRYQSEK CocheC53 PLFVTWLRGCIGTFEPLSTGLSSYALTSAFDDTRFPPILECAVTLLTHFEMDWEV-GVHGLRIGSTYLPDVAREQGWTKEETIVSLMR-KAGWGGVVRYQGKK Coere1 PLFVTWLRGCIGNFAKLGTGLREYALISALNDSRFTPILSCSVSLLTDFELDWKI-GEHGVWITATFLPEIAKEQGWSKIETIDHLLR-KGGYQLLTRYQSKK Conco1 PLFVTWLRGCIGNFGDLVEGLKDYALISALQDTRFSPILSCSVSLLINFQLDWKV-GKHGIRITATYLPEVAKEQGWDQETTIMHLLH-KGGYRSVITYESEK Conpu1 PLFVTWLRGCIGNFEPLRDGIAEYALISAFKDSRFRKILECGVSLLTDFELDWTV-GTHGIYITATYLPDVMPEQGWDKVEAVDSAIH-KAGWKGLRRYQSRK Copci PLFVTWLRGCIGNFEALHEGLAEYALISAFKDSRFRKILECSVSLLTNFELDWTI-GVHGIYISATYLPEVIPDQGWSKIEAIDSAIH-KAGWRGLRRYQSQK Croqu1 PLFVTWLRGCIGNFSPVRDGLKDYALISALKDHRFPPILSCSVSLLHSFELDWSI-GKHGIYLSATYLPDVAAEQGWTKLDTINSAIQ-KAGWSGIERYQSSK CryneH991 ALFVSWLRGCIGNFLPLAEGVKDYALISALKDHRFSPILLCE------------------------------------------------------------- Crypa2 PLFVTWLRGCIGTFSPLSSALSEYAIISALHDSRFAPVLRCAVTLLTNFEDDWTV-GEHGIRIGSTYLPSVAPEQGWDKEQTMLSLMR-KAGWEGVERYRGDK Debha1 PLFITWLRGCIGTFQPIESGTKRFSLTSSLQDPRFPPILSVSVTLLDNFEDDWTV-GDHGLKVLGTFLPSVAVEQEWDKITTLAYLLK-KADYTGLVRYEGVK Dekbr2 PLFVTWLRGCIGNFSKLPDGVKQYAVIAAMEDPRFDPILSCSVTLLKNFEYDWEI-GKHGIRITATFLPDVASEQNWTKQQTLQALVE-KAGFYELTRYQGIK Dicdi PLFVTWLRGCIGTFANLVEGLHKFALTSALKDSRFSAILHCAVSLLVKFEWDWEI-GTHGIWINSTYLPDVIPEQEWTKEEAIRSLIK-KAGYNGLTRYQSSK Dmel PLFVTWLRGCIGTFSELHHGLREYALTSAFKDSRFAPILTVSVSILQNFELDWQL-GVHGIRITATYLPQVATEQGWDQLQTIDSLLR-KGGYRALTRYRSQE Enthi GCFVTYLRGCIGCFSPFYQIVKKYC-KYALHDDRFDPMVDIAVSMLTEPILKAVIPGVHGIIVNGTYLPEVCTEENWDVKTFVTHCARYKAGIYGWQTY-KSI Falba AAFLTWLRGCTGTFQPVGPLIRQLAIGSAVRDTRFPPVLRATVSILHSFENDWQI-GTHGIEIGATFLPSVMVDHGFSHDDTFDYLVD-KAGLRLITRYQTAT Fomme1 PLFVTWLRGCIGTFDPVHEGILDYAIYSAFKDTRFAPILECAISLLTDFELDWTV-GIHGIYITATYLPDVMPEQGWDQLDAIDSAIR-KAGWEGLRRYQSSK Fusgr1 PLFVTWLRGCIGTFEDLSEGIPEYALISALHDSRFSPVLQVAVTLLTDFEFDWEI-GVHGIRLGSTYLPDVASEQGWTKDETLFSLIR-KAGWTGVTRYQGKK Galma1 PLFVTWLRGCIGNFEPIHQGLADYALISAFRDSRFRKILQCCVSLLTEFELDWTI-GVHGIHITATYLPDVIPEQGWDKIEAIDSAIH-KAGWRHLERYQSSI Ganpr1 PLFVTWLRGCIGTFEKIHKGLEEYALISALRDRRFSPILSCGVSLLTNFELDWEV-GQHGIWITATYLPEVAEEQGWTKLEAIDSLLR-KGGHQGLTRYRSEK Gloin1 PLFVTWLRGCIGNFEPLHSGLKEYAITSAIHDRRFSPILTCGVSLLTNFELDWEI-GVHGIWITATYLPEVTEEQGWTKEEAIDSLLR-KGGYNGLTRYQSAK Hisca1 PLFVTWLRGCIGTFEELAAGLKTYALTSAFGDTRFPPILSCSLTLLSSFELDWVL-GTHGLRIGATYLPDVAVEQGWTKEETVESLMR-KAGWEGTVRYQGLK Klula1 PLFVTWLRGCIGTFSKIEEGLKRYALISALQDSRFTPILRCGCNLLSQFKWNWEI-GKHGIEISATFLPEVIPEQGWDQRETFENLIE-KAGCWNVIRYEGTK Lacbi2 PLFVTWLRGCIGNFEALHEGLADYALISAFRDSRFRKILDCAVSLLTDFELDWTI-GVHGIYISATYLPDVIPEQGWDKIEAVDSAIH-KAGWKGLRRYQSSK Lenti61 PLFVTWLRGCIGTFEPLREGLSEYALISAFRDSRFKKILECKVSLLTDFELDWTV-GVHGIHISATYLPEVAEEQGWDKIEAIDSAIR-KAGWNGVRRYQSSI Malgl1 PVFVSWLRGCIGTFEPLSQALQVYTIQSAWNDKRFEPILQCTVSLLTPFEFDWEM-GVHGVYVTATFLPEIAPAQGWSKQETIVHAIL-KAGWSGLWRYKSTT Mellp23 PLFVTWLRGCIGNFSPINEGLKDYALISALKDHRFPPVLSCTVSLLHSFETDWTI-GKHGIYISATYLPDVALEQEWVHLEAIDSAIR-KAGWDGIERYQSSK Mnele PLFVTWLRGCIGTFTNLHKGIKEYALTSAMNDSRFNPVLSVSVSLLVGFELDWTV-GIHGIKITATFLPDVAKEQGWTKEETVEALLK-KAGVRGLIRYRSEK Monbr PLFVTWLRGCIGTFAPLAEGLQTFTCSSAFRDSRFPPILQCGVSLLTNFTLDWEV-GRHGIWITATYLPEVAAEQGWTKEEAIQSLLR-KGGHRGLTRYESQK Morel2 PLFVTWLRGCIGNFSPLHSGLKEYALTSAFKDGRFPPILVCGVSLLVDFELDWEV-GRHGIWITATYLPEVAKEQGWTKEKAIESLLR-KGGYRELTRYQSRK Mucci2 ---------------PLHTGLTKYALVSALQDRRFSPILTCAVSLLTDFELDWEI-GIHGIWITATYLPEVMEEQGWTKQEAIKSLLR-KGGYYGLTRYQSQK Mydma PLFVTWLRGCIGTFSKLHDGLKEYSLSSALRDSRFSPVLHCSVSLLTNFELDWEV-GVHGIRISATYLPEVAQEQNWNQVQTIDSLVK-KAGYWNLTRYRSEK Neucr2 PLFVTWLRGCIGTFEPLSSGLPSYALTSALQDTRFHPILQVAVTLLTDFEMDWEL-GKHGLRIGATYLPDVAPEQGWTKEETVVSLMR-KAGWEGVVRYQGKK Orpsp11 ------------------------------------------------------------------------------------------------------- Pench1 PLFVTWLRGCIGTFEELAAGLKSYALTSAFDDHRFDPILSCSLTLLGSFEMDWSL-GTHGLRIGATYLPDVAVEQGWTKEETVESLMR-KAGWDGTVRYQGLK Phybl2 PLFVTWLRGCIGSFRPLIQGLKQFALNSALEDSRFPPILSCAVSLLINFELDWEI-GKHGIWITATYLPEVMPEQGWTKEETIQSLLR-KGAFRGLTRYQSSK Picst3 PLFITWLRGCIGTFLSIESGISRFSLTAALQDPRFHPILKVSVTLLDNFVDDWKI-GLHGLRILGTFLPSVAEEENWDQTTTLYYLLK-KADYNGLTRYDGLK Plicr1 PLFVTWLRGCIGNFGPIREGIAEYALISAFKDYRFNPILECCISLLTDFELDWTI-GVHGISISACYLPDVIPEQGWDKIEAVDSAIH-KAGWNGLRRYQSKT Polpo PLFVTWLRGCIGTFSPLVKGLNEYALTSAFKDTRFKPILHCAISLLVNFEWDWEV-GKHGILIRGTYLPEVMPEQEWSQREALESLIK-KAGYYGLTRYQSSK Pucgr2 PLFVTWLRGCIGNFAPLNEGLKDYAVISALKDHRFSPILSCTVSLLHTFETDWTI-GQHGIYISATYLPDVAGEQGWTKVEAIDSAIR-KAGWRGIERYQSSK Punst1 PLFVTWLRGCIGTFEPLREGIAEYALISAFTDSRFRKILECGLSFLTDFELDWEV-GTHGIRISATYLPNVAPEQGWDRVETIDSAIR-KAGWNGVRRYQSRK Rhior3 PLFVTWLRGCIGNFSKLHEGLLKYALISALKDTRFKPILSCAVSLLTDFELDWEI-GVHGIWITATYLPEVIKEQGWTKEEAIRSLLR-KGGYYGLTRYQSQK Rhoto1 PLFVTWLRGCIGNFEPLGEGLADYAKISAFQDHRFDPVLECGVSLLTDFELDWEL-GTHGIYVHATFLPDVAPAQGWSKVDAVDAAMR-KAGFKGVSRYQSKK Rozal11 PQF-----------------------TSAFNDSRFSPILSCAVSILDDFEDNWDV-GIHGIKISATYLPEVAHNQGWTKYETIVSLLK-KAGYYGLVRYQSRK Sacce1 SLFITWLRGCIGTFAPIAHGIEKYSLIAALEDRRFSPILKCSCNILGNFKFDWEL-GKHGIELSATFLPDVMPEQHWNKEDTFANLIE-KAGYWGVIRYEGKK Salro PLFVTWLRGCIGTFSPLHEGLREFALTSALRDTRFDPVLQCGISLLTNFELDWEV-GTHGIWITATFLPEVMPEQGWSKVEAIDALLR-KGGYTSLTRYKSHK Schco3 PLFVTWLRGCIGTFEPLHEGIPEYALISAFRDHRFRKILECGISLLTDFELDWTL-GVHGIRISAVYLPDVMPEQGWDKIESVDSAIR-KAGWTGLVRFQSRK Schpo1 PLFVKFLRGCIGTFRPLVTNLTYFSKQAAFCDERFRPILECQIDLLVDFELDWEV-GIHGVSISSTYLPSVAAEQRWDQEETLESLIH-KAGYYGATRYKSLE Sorma PLFVTWLRGCIGTFEPLSSGLPSYALTSALQDTRFHPILQVAVTLLTDFEMDWEL-GKHGLRIGATYLPDVAPEQGWTKEETVVSLMR-KAGWEGVSGEEGEV Sphar PLFVTWLRGCIGTFSKLHLGLKSYALSAALEDSRFDPVLQCTVSLLIDFEMDWEI-GIHGIWITATYLPEVMSEQGWTRMEALESLLR-KGGHVGLTRYKSEK Spipu1 PLFVTWLRGCIGNFDPLHSGLKEYALTSSLRDRRFSPVLSCGVSLLTEFELDWEI-GTHGIWISATYLPEVAAEQGWTKLEAIDSLLR-KGGHTGLTRYQSSK Sporo1 PLFVTWLRGCIGNFEPLREGLTDYAAISAFRDHRFDPILQCGVSLLTDFELDWTL-DVHGIY-HATFLPDVAGEQGWSKVDXVNAAIR-KAGYKGVSRYQSKK Stehi1 PLFVTWLRGCIGNFEPIRDGIAQYALISAFRDHRFRKILECAISLLTDFELDWSI-GTHGISISATYLPEIAPEQGWDKIETVDSAIR-KAGWSGVRRYQSRK Tapde11 ------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------- Treme1 ALFVTWLRGCIGTFSPLSKGLKEYALIAALQDHRFSPILICGVSLLTPFILDWTP-GIHGIHISATYLPEVCLDQGWTREECILSAIQ-KAGWRGVQVYESVK Trire2 PLFVTWLRGCIGTFEPLAEGIPEYALISALQDTRFRPILQAAVTLLTDFEHDWEV-GKHGIRIGATYLPDVALEQGWTKDEALFSLIR-KAGWMGLTRYQGRK Umbra1 PLFVTWLRGCIGNFDPLHSGLKQYALTSALHDRRFNPILSCGVSLLTNFELDWDV-GTHGIWITATYLPDVIPEQGWDKIEAIDSLLR-KGGFQGLKRYQSSK Ustma22 PLFVTWLRGCIGTFEALAQGLAEYASISAFKDSRFSPILECGVSLLTDFELDWQV-GVHGIYITATYLPDVIPEQGWSKLDAIDSAIR-KAGFTGVTRYRSDK Walse1 -MFVTWLRGCIGTFKELIKGLRQYSLISALEDKRFDPILSVSISILHNFKFDFKI-GLEGIKIQSTFLPNVLTEQNWTKEQSIVAAIK-KSGYRQLETFESEY Zygro1 SLFITWLRGCIGTFAALVHGIEKYSLVAALQDNRFPPILKCSCNILQNFTNDWEI-GLHGIELSATFLPEVMSEQNWDKEETFLNLIY-KAGVSSVIRYEGNK [Cluster2026.fasta_al_trimmed; alignment length = 166] Allma1 WRAVSLVLLDGR-AVKTP-KGTPLTVPMAYMVSGEWESQDKL-IKPYSLPLTSLVVRAQDLMKFLDTDATCYHSLVELQQQHWDPLVDWVRTTFQYTPHQMACFEKAVLASKSFVIGLALVSGQQASDAARVEVMSQIARFGEVEDAHDVDREDMQRQMAAIAVGV Ashgo11 WDKVDLVHIDGK-PVRTP-LGSPLRVDLAHMLREEWAGLTSLAVKPYSLPLTSLVSRCIDLLRYLDTDTLLCFSLRKAQDEMYKPIIAGVETLLNLSVWDFAVFEKVVLTTKSFICGILLLSTEEIARAATLETIYQVERWGEVEDTHDVNHRDIRRNINAAAVVA Aspfu1 WKNVDVVLLDTR-PIRTP-TKDILSIPLAHAIALEWDSARQA-LKNHLIPLTSLTARAGDAMRYLDTDTLLCWVLREAQMRVAKDIIAFLGTKVSLQPHDLAALERGIVASKSLLVAVRLVGIEEAAEASSLEVRWQTDMWGEVEDTHDVDKEDLRRQLGSVIVVV Aurde31 WKDADLITLDKR-PLKTP-GGNVLEIPLATMIAYEWDNQEKL-IKPHALPLTSLAARAIDLLKYLDTDSICFHELVQLQAQHWQPLLDWARAEFRLDPWQLTALERAVYSSKSLIIALALVNPEQAAQAAHVEVSSQVQRWGEVEDSHDVDFQDIRRQLGSVACLL Batde5 ------LLLDGR-ILKTP-DGNQVVIPFAALTAAEWEGQDKV-LKSHSLPLTSIIVRAVDMLKYVHTDSICYQQLVELQKCYWNPLVDWLKEAHGYDNIKLAAFEKAVMRSKSFIIGLALMSVEFATTAGRLEVIHQIEKWGEVEDSHDTDREDLARQLGACTCAI Botbo1 WKTVGIVTLDNR-GLKTP-DGNPLAIPLATLIADEWENQEKL-IKPHALPLTSLASRVIDLLKYLDTDTVCFHELVELQHKHWDPLLEWARAEYGLDNWQLAAMERAVYTTKSFIIALALISVEEASEASHVEVNSQIRKWGEVEDSHDVDHRDVRRLLGSVACVL Botci1 WKDVNVIFLDKR-ALRRP-SKDILTVPLASAIALEWDSAQQA-LKTHLIPMTSLVNRALDVMRYLDTDSLLCWALRSIQRKSAEPIIQFLSEKVGLPPFELAGLERGVLAGKSLLGAARLVGVEEAAKAASLEVDWQTGMWGAVEDTHDVEREDIRRQLGSVVLLV Caeel YKEVSVVLLDHR-VLKTQ-GGQVLKLDLALAIAEEWSSQDEF-LQLGQMRLTGLAFTAQDILDYVEGDTVLFFNLHRYQEEKWAPLIKNLNNDLQHNFPALVGLQYATESVKSFVIAYNAIDPDTAIDAATLEQRTQAETWGNVEWAHGIEREELMTRLSAACLFV Canalb1 WKKGEVIQLDGK-TLRTP-LGFPLELPLAYLIAHEWTHLPDIKVKSSTLPLTALATRAIDMLRYLDTDTCLIFALRKRQEEIYRPLINEFNEFFQLPIYDLIALEKTILTTKSFLCGITLLTLEELVELGNLETIYQTEEWGEVEDTHDVDKHDWLRNLASAALVC Cangl WDQVGLVQLDSK-PLRTP-LGNNLAIDLGLMLKKEWSNLQEVASKKFSLPLTSLVSRCIDLLRYMDTDTLLVFSLREEQDKLYLPIIKKIEEFLSLSPWDLAVFEKTVLTTKSFICGILLMSLDEIIRLATLETIFQVERWGEVEDTHDVDKRDIHRKISSAAIVA Capow YRSVTVIKLDDR-QLRTP-ARSLLVLPLAVGVAGEWDSQRPT-IKPHLMPLTALSNTATDLLRFLATDTVCCRTFQEMQSTHWDPLVHWFTKRFNMNEWTFTGLETATLTAKSMVIAAALGDANQATICAHLEEEFQTERWGKVEWGHGMRHADTRMTLAAAGLFM Catan2 WRAVTLVLLDGR-VVKTP-QGTPLSIPIAHLVSAEWESQQKL-LRAFSLPLTSLLVRAKDLMKFLQTDATCFHELVRLQQAHWDPLLDWARTHFQYSPLQLAAFEKAVLTSKSFLIGLALTSAQQAADAARVEVQAQIDRWGEVEDAHDVEREDIQRVLAASALVV Cioin YKEARIINLDNR-KLRTP-NGNIVKLPLAQAVSVEWNNQNKV-LKLDQMPLTTLCFSAVECFNYLHTDTILCRILEKFQSERWDPMVNWLMKRHSYNYWSIIGFERMVSSLKSLIVPLALVSVEEAVSLSRLELEYQISKWGNIAWHHDIELAESRMKTAAAVMFI CocheC53 WKDVSVVFLDHR-PVRMP-NKQILTVPLAAAIALEWDSAQQA-LKNDYIPMTSLAARAIDFMRVLSTDTLLCWALRQIQEEVAMGIIAYLQTHVGLPAYELAGLERAVLASKSLLVSARLVGINEAAEASSLEVKWQTVQWGEVEDTHDVQREDLRRQLGSAVVLV Coere1 WRDVSVVLLDKR-PIKTP-DGKLVRISLAWLLAGEWESQKDT-LNAHSLPLTSLVSRSIDLLNYFQTDSVCLHDLVDLQQKYYSPIVDWARSTYEFSPLKLAALERAVMSAKSFLIGLALVTVEEAAMAAQAEANAQTQFWGELENAHDLDNTAMRQVLGASACTA Conco1 WKNVSVVKLDGR-SVKTP-IGTKLVVPLANLIAGEWESQQKI-IKPHSLPLTSLVARSIDLERYLHTDTLCYRQLNELQDIHWTPVHNWVNEKFGFDPLTLAAFERAVIASKSFILGLQVIKLEEICQASQVELKYQQDFWGEVEDAHDVAEQDLLRQLGAAKMVV Conpu1 WKTVGVVTLDSR-PIKTP-AGNTLLLPAASLIAFEWENQETV-LKPHALPMTSIASRAIDLLDYLHTDTICFQNLVELQTKYWDPLLDWARKTFKMDPWELAVMERATYTTKSFIISLALITAEQAALASQVEVASQIQRWGEVEDSHDVDFHDVRRQLGSAACLL Copci WKEVGIVTLDKR-ALKTP-SGNTLLLPVAALIAAEWDHQETL-LKPHALPMTSIVSRAIDLLNYLETDTVCFFHLHRLQTKYWVPLIDWARSALALDRWELAALERATIATKSLIIGLALVTVEGAALAASVEVDSQIERWGEVEDTHDVDYQDVRRQLGSAALLL Croqu1 WKTVDIVRLDKR-KLVTP-AGNQLVIPLAILVAREWSEQRKV-LKQHSLPLTSLVSRAIDLLSYLDTDTICFFELVDLQEKYWKPLIEWINQSYEFDQLKLAGFERAVHVTKSFVIALALVTVDEASDASRVEVLSQIARWGEVEDTHDVDFQEIRMKLGSVACSL CryneH991 WKTVNIITLDHR-ALKTP-FGAKLEIPLAALIANEWENQDEV-LKQHALPVTSLASRAIDLLKYLETDTILYPHLVRLQKEHWDPLYKWLKEDFTMDGWELAAFERAVYATKSFVIALALCTAHEAAQASHVEVSSQIERWGEVEDTHDVDYQDIRRALGSAACLL Crypa2 WKDVHVIYLDAR-PLRHPETKEIVNIPLAYALALEWDSAQQA-TKQHLIPLTSLTCRALDVLRYLDTDSLLCWALRELQERTAGAIIGYLSTHVGLDAWELAALERAALAGKGLLGAARLLDVEEAARVASLEVDWQTSKWGEVEDTHDVEKVDLRRQLGSVVLLV Debha1 WEKVDAVQLDGK-TLKTP-LGFPLSLPLAHLVAHEWANLPDLKVKINALPLTSLSSRAIDLLRYLDTDTCLIFTLRSKQDELYFPLIKEFEDYFDLSMYELVALERAILTAKSFLCGASLLTVEELVELGNLEIIFQTEEWGEVEDTHDVDKVDWLRHLSSSALLT Dekbr2 WEKVSCIMIDGK-TIKTP-LGFKLEIPLAYLLTNEWKSLPSLHVRPYILTLTSLSCRAIDLSKYLDTDTLLVFSLRKEQQKLYYPLKKEMEEFFSLDTWELVALERTTLTCKSLLCGVAVVSLDDLARAATLETVMQTKRWGEVEDTHDVEKVDVRRVLSASSLLC Dicdi YKTAGMPLIDER-KIRTP-SNHVIITPIAYAVAAEWRAQEKY-IKPSRLPITQTIISCLDFINHLATDPICNRELKKLQSELYEPILQFANEYYSMNNWELVCLQLISQSSKSFLVALSLYRLDNLYQTIALEEEYQSETWGRIPFGHDLAECETHNEIAPPLFML Dmel YKKTSVVVLDHR-KLKTP-KGTPFIVRLAIAVATEFDAQKEN-IERSRMHLSALCFTAIDLLNFIATDTVLFQYLQDLQVNEWDPVIAWFNQRYSYSLETLHGFIFAVDTLKSIVLACAVITVEKAVALARLEEEYQLKFWGRVEWAHDLSQQELQARLAAAVLFV Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba WKAVSTVFLDAR-PLRTH-LKQLFEVPLAELIAAEWSSQREH-LKPLALPLTSLISRALDLVAYLHSDTLCFPELVERQNREWTPIRRWVEAEYELHPWQLVAFEEAVISSKSFILPLALLTLDQAADASRLETLYQVGRWGQVEDTHDVDHYDIRTRLGAALLMH Fomme1 WKTVGIVTLDRR-ALKTP-SGNILILPAAALIANEWENQDKV-LKPHALPMAT--SRAIDLLKYLETDTICFHELVRLQDAHWQPLLSWIRDEYAFDEWQLAAMERATYTTKSFIIALALIDVEQAAQAGHVEVNSQIEKWGEVEDSHDVDYQDIRRQLGTVACLV Fusgr1 WKDVTVVFLDTR-PLRHPSTKAIVRIPLASALALEWDSAQDA-TRHHLIPLTSLTCRAIDLLRYLDTDSILCWNLRDVQKRTADDIVSFLTTHVGLDAFEIAGLERAGLAGKSLIAAARLVGVEDAAVATSLEVNWQTMQWGEVEDTHDVNKEDVRRQLGSVVLLV Galma1 WKDVGIVTLDRR-ALKTP-SGKTLLIPSASLIAAEWDHQEIL-LKPHALPMTSIVSRAVDLVKYIHTDTVCFFHLEKLQSKHWTPLLDWARDTFSLDHWEMAALERATYASKSLIIALALVSVEDAALAATVEVNSQIERWGEVEDTHDVDYQDVRRQLGSAACLI Ganpr1 WKTADVILLDGR-PLKTP-TGKQMILPLATLVAAEWE-SVKL-LKQYSLVLTSLAARAVDLCKYIHTDTICYRQLIRLQQRHWDPLIKWLQEEYGMDPFELAAFERATLHTKSFVTGLALVTAEEAAAAARVEVQHQIDMWGEVEDAHDVDAADMKRHLGAAVTAI Gloin1 WKQVSIILLDKR-PLKTP-GGSKLTVPLALLIAGEWESQNHV-LRQHSLPLTSLISISIDLLRYFDNDTICYHELVELQKKYWLPILDWVQNTYNFDSLKLSGFERATMISKSFLIGLALVSVEEASKASSIEMNSQTIRWGELE-AHDIENEDVKRHLGSVSCTV Hisca1 WKDVHVIFLDSR-AVRTP-AKKILTIPLAHAIALEWDSAQQA-LKQHLIPLTSLTARAQDTMRYLDTDPLLSWAHRQT-----------------------ESLHRM-----------------SSPCANGEKAEQKDQKFRSVHIRSRVNSQRASHMLFYCAIVA Klula1 WEQVSLIKLDSK-PLRTP-LGNPLTLPLSVMVLNEWSNLPSLSVKPYVLPLTSLVSRCIDLLRYLDTDTLLVFSLRKAQDELYLPIISGVEKFLSLSVWDLAIFEKTVLTTKSFICGLLLLSMEDIARAATLETIYQVERWGEVEDTHDVDKRDVRRNIHAAAIVA Lacbi2 WSTVGVITLDGR-ALKTP-SGNTLLLPLASVIAAEWDNQETL-LKPHALPMTSIASRAVDLVAYLDTDTICFFNLEKLQTQHWEPLLSWARETFSLDKWEIAALERATYTTKSLIIALALVSVEKAALAAQVEVNSQIERWGEVEDTHDVDYHDVRRQLASAAILL Lenti61 WKNVDIVTLDKR-PLKTP-SGKRLIVPVAALIASEWENQQTL-LKPHALPMTSLASRALDLLKYFETDTVCYHALVKLQETHWKPILDWARSTFKFSPWEMAAMERATYTSKSFLIALALVDVDQAAHAAHVEVNSQIERWGEVEDSHDVDYHDIRRQLGSASCLL Malgl1 WKDVFLVQLDRR-NLRTP-QGAKLAIPLACLIAQEWDEQTKV-VKPHSLPLTSLMSRAIDLMRYFDTDAVCFHDLVRLQEERWTPLLDWMRRSFGLQPLDLASLERAVMTSKSMIIGLALIEAEQAALAAEVETASQVAAWGAIDDTHDVDHAELRRQLASVACAQ Mellp23 WKTVDIIRLDQR-KLVTP-SGNQLVIPLAVLVAREWAEQRKI-LKQHSLPLTSLVSRSIDLLNYLDTDTVCFFELVDLQDKHWKPLIEWISQTYHFDRLKLAGFERAVHVTKSFVIALALVTVDEASDASRVEVLSQIARWGEVEDTHDVDFQEIRMKLGSVTCAL Mnele YKDVDVVTLDNKFNVKTP-GRNLLVLPIANAVAVEWDSQRKN-IIFALMPLTYLCFKATDTLEFLRTDTVCYRALQSMENNRWNPLTDWFSEHFKQHPWALPAYHHSTTSLKSLVIAMAMLSAEEAIACSYLESDYQIDRWGEVEWQHTLDKARLSADVAAAVLLV Monbr WHKESIVFLDQR-HLKTP-MGKKFSVHLAHIVAMEWATQGEH-LTPATMYVSALSNTALD-------DTVVFRDLSTFEARSWDPLVSKFQERYHLPHWQLSAMELATDTTRSLVIALAMLTAQEAADAARAEVEFQIQRFGRVSWSHGMEQADTEGRLSAAALVM Morel2 WETASVVTLDGR-VLKTP-AGNPLTLPLALLIAGEWHGQKAL-LKSHSLPMTSLVARAIDLIKFLDTDSICYQQIVKAQEKHWDPILKWVKEKYAMSDIELSAFERATLTAKSFLIGLAVVSVEKAWAAAQLEVLDQIERWGEVEDSHDVDREFVKSQLASARLAN Mucci2 WKRAGIVVLDQR-NLRTP-SKHIVQFPLALLTAAEWDAQTKN-LKAHTLPLTSIVARAIDLMLYFDTDAICYHELTQLQDTYWKPIIHWAENTYQMGPLELSAFEKAVMSSKSFLIGFALVSVEHAAQAAHVEMNAQMDRWGEVEDSHDVEREFIRQTLGSVAITL Mydma YKEVTLIQLDKR-TIKTP-LGKPLLVPLGIAVANEWHMQDSD-INTSVMPLTVICNTAIDMLRYFQTDTICALALVELQAREWVPIINWFSKWHNLNRWQIYGLQSAMEITKSFILPMVVSSVEKAVYLSRLEVEHQITKWGNVEFAHELEKQNQTIFLAAGILFY Neucr2 WKSVHVIHLDSR-PLRRPDTKSIIRLPLASALAIEWDSAQQA-TKQHLIPLTSLVCRALDLLRYLDTDSLLCWALREVQEEAYSSVVSFLTTRVGLSAWELAALERATLAGKSLLVAARLVGVEEAAKAVSLEVDWQTTQWGEVEDTHDVEKVDLRRQLGSAVLLC Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 WKDVHVVLLDKR-PVRTP-MKEVLSIPLAHAVALEWDSAQQA-LKSHSIPMTSLAARATDAMRYLDTDTLLCWELRQIQTRIAGNVMSFLSTKVELSAFDLAGLERAILASKSLLIAVRLVGIEEAAEASSLEVTWQTDMWGEVEDTHDVGKEDLKRQLGSVVVLV Phybl2 WKRAGVVILDHR-NLRTP-SNNVMRFPLALLTAAEWDAQTEN-LKAHTLPLTSIIARAIDLMVYFDTDATCYRELVRLQEQHWSPIHAWIKEKYAMDNLELSAFEKGVMSSKSFLIGFALITVEQAAQAAHVEMNAQMERWGEVEDSHDVEREYIRQTLGSVACAV Picst3 WEKVDTVQLDGK-TLKTP-LGFPLALPLAYLIANEWANLPDLKIKTNMMPLTSIAARSIDMLRYLDTDTCLIFTLRKRQDELYLPLIAEFEDFFLLPIYDLIALEKAILTSKSFLCGVTLLTVEEIVELGNMETIFQTREWGEVEDTHDVDKVDWLRNLTSAALLC Plicr1 WTTVGIVTLDAR-PLKTP-AGNPLRLPAAALVASEWERMETV-VKPHALPMTSLVSRAIDLLEYLDTDTICFHQLEALQKTHWDPLLAWARTTFGLDCWELAALERATTTTKSLLIGLALVSAEQAAQAAQVEVASQIERWGEVEDSHDVDYQDVRRQLGSAACLL Polpo YKHVGYPLLDNR-PMKTV-NRKLFIVPIAMAIATEWMVQGKY-IMPHRLPLTTVAATCIDLIGHLATDQVCNRDLKKLQNEAFDDLLHWSSDYYSMNNWQLLCMQTLTTSTKSFLISLNLYRLDKLYKIVALEEEFQSETWGKIPFGHDLAEMETLNEIAPALFVL Pucgr2 WKTVDVIRLDLR-NLKTP-SGKPLVLPLATLIAREWDEQRKI-LKQHSLPMTSLASRAIDLMRYLDTDTICFQELAEMQKTHWAPLLVWLQEAYQFDPLKLAAFERAVHATKSFVIALALVTVDQASDASRVEVLSQIARWGEVEDTHDVDYQEIRMKLGSVSCAI Punst1 WKTVGVVTLDQR-TLRTP-GGNRLLLPVAALVATEWDNQETL-LKPHALPMTSLASRAVDLLKYFETDTICFHELVELQKKHWHPILDWARSTFSLDAWELAALERTTYVTKSFLIALALVTAEEAALASHVEVNSQIQRWGEVEDSHDVDYHDVRRHLGSASVLL Rhior3 WKQAGIVVLDQR-NLRTP-SKHIVQFPLALLTAAEWDAQTKN-LKPHSLPLTSIIARSFDLMSYFDTDSVCYHELVRLQDAYWKPIIEWTEKAYQMDALELAAFEKAVMSSKSFLIGFALVSVENAARAAHVEMTHQMERWGEVEDSHDVEREYIRQTLGSVAVAL Rhoto1 WKTVGVVLLDKR-TLKTP-GGVPLLVPVALCIADEWENQKSV-LKPHTLPMTSIAARAIDLLRYLDTDTVCFHELVKLQEAHWKPLIDWVEKTYDYDAYKLAAFERAVLASKSYLIALGLVSVDEAAKAAHVEVQSQIDRWGEVEDTHDVDHQDVRVRLGSAALLV Rozal11 WKTSVVILLDSK-PIKDQ-KGRPFTLKMANLVSLEWNMQPQM-FNPNDIILS--------LFRYLDTDTLRYFELVKLQESNWLPLVEWASHLLDVNHNTFAAFERAVISSKSMIVGLALVSSKEAIEISLLEINYQKSRWGSIDEFHLLEPATLQRVFSLVNLLK Sacce1 WEKVSLLQLDGR-TIKTP-LGNGIIVDLAYLLKLEWSSLSSLSIKTHSLPLTSLVARCIDLLRYLDTDTLLVFSLRNAQNELYIPIIKGMEEFLSLSPWDLAILEKTVLTTKSFICGVLLLDMDNIVRAATLETIFQVEKWGEVEDTHDVDKRDIRRKIHTAAIAA Salro YEKASVVHLDKR-SLKTP-KRNTFVVPLAHTVAFEWDVQGDV-IEPSSMNVTLLCNTAIDVEPFMRTDTVCFRELIDMQSEIWDPIVEWFAMRYGMTPFELTAYELAADTAKSAVIALALRNAQEATAAARLETDFQTSRFGEVEWAHTIEKHDTQARLAASAIVM Schco3 WKDVDVVTLDRR-ALKTP-SGNTLLLPVASLIAAEWESQSTV-LKPHALPITSLASRAIDLLDYLHTDTICFHQLVTLQKQHWDPLLDWARKTYELDQWELASFERATHVTKSFLIALALVNVEQAANAAHVEVNSQIQRWGEVEDTHDVDYHDVRRQLGSAACLL Schpo1 WKNTATIQLDGR-NLKSP-SGKIVKVPLAHLIALEWDRLPSTSVRQHNLPITSLVSRAIDLIRFLDTDTILIYSLLEEQKENWWPLKETFENKLSLNSWQLAAFERSVSCCKSFIVSFMILNSEKAAALTNLELQYQTNRWGSLEDAHEIDNEDLKNKLASSAILS Sorma WKSVTVIHLDSR-ALRRPDTKSIIRLPLASALAIEWDSAQQA-TKQHMIPLTSLICRALDLLRYLDTDSLLCWALRELQEEAYSTVVSFLTTRVGLSAWELAALERAALAGKSLLMAARLVGIEEAATAVSLEVDWQTNQWGEVEDTHDVEKVDLRRQLGSAVLLC Sphar -------------------------------IAAEWNSQDGI-IRPHAMHLTGMANSALD---------------------------AYFNQRFSLNPFEITAMENAIAMCHSAIVAVAVMSVEKVQTSS-------LQHRG------------------------ Spipu1 WKKVAIVTLDGR-SMKTP-DGNPLVIPLALLVAGEWEGQAKL-LKSYSLPLTSIIVRSIDLLRYVHTDSICYYQFVKLQDEHWRPLMAWMKEEYDFDLITLAAFEKAVLSSKSFIVALALVTVEDAAKAARLEVLHQIDRWGEVEDSHDVDREDLTRQLGAVACSL Sporo1 WKSVALVLLDKR-TLKTP-GGLPLLMPVALLIAEEWENQVAV-LKPHTLPMTSIVSRALDLLKYLDTDTVCFHELVKLQEEHWEPLLDWVRETFDYDQFKLAAFERAVLASKSYLIALGLVTVDQAAQAAHVEVQSQIDRWGEVEDTHDVDHQDVRVRLGSAALLC Stehi1 WKTVDVVTLDKR-PLKTP-SGNQLLVPVATLIASEWENQLTL-LKPHALPMTSLTARAIDLLKYLDTDTICFHAVVRLQNEHWMPILDWVRSEFEFDQWEMAAMEHVAYTAKSFLIALAVVTVEQAALAARVEVSSQIERWGEVEDSHDVDHHDVRRHIGSAACLL Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr YKEVGVVTVDGR-VVKTP-MRAPLVLPLAVAVAQEWDAQRTH-IEPLFMPLTKFASTVLDLVKYLASDSLAFRNLAALQHKKWDPVVEWVGQNHALDDWQLVGFDRIAASTRSVTLSLALTSPEQTLALSRLEEEFQTGVWGVVEGGHDIDETVAMVDLTATDVYL Treme1 WKTVNIIALDHR-HLKTP-AGTKLVIPLAVLIANEWENQDEV-LKQHALPVTSLASRAIDLMKYLETDTVLFPQLVRMQQEHWQPLFDWLRNELEMDTWELAAFERAAYASKSFIIALALCTADQAADASHVEVRSQIERWGEVEDTHDVDYQDIRRALGSAACMV Trire2 WKEVTVVHLDAR-PLRHPNTKAIIRLPLASALALEWDSAQQA-TKQHLIPLTSLVCRALDVLRYLDTDSLLCWALRDVQKKAAEETVSYLTTHVGLDAWEIAGLERAVLAGKSFVAAARIVSVEQAAKATSLEVDWQAEQWGEVEDTHDVNQEDVRRQLGSVVLLV Umbra1 WKKASIVQLDGR-NLRTP-SKNKIMLSLAQLLAAEWDGQLSN-LKPHSLPLTSLLSRAIDLMSYLETDTICFHELVQLQAQHWKPILQWIEKQYDMDPLELAALERAVISSKSFLIGLALVTVEQAAQAAHVEVNSQIDRWGEVEDSHDVEKEYIRQALGSVACVV Ustma22 WKTVSLILLDGR-PIRTP-SGSAIVIPLATCIAQEWCEQGKL-LKPHTLPLTSLAARALELLRYLENETVCFQELVELQSLHWDPLLSYINSTYALHPFDLAAFERSVLLTKSFLISVALVSVQQAAQAAEVEVQSQINRWGSVEDSHDVDHAQMRTTLGSVAIAT Walse1 WKTANVVHLDTR-KLRTP-AGNVIDLPLALLIAHEWQSQDKV-IKAHALPITSLASRALDLIKYFETDATCYFELVELQEKHWRPIVEWANKRYQFDAFTLAAFERIVMHTKSFLIALAVVSIEDASQAARVEVLSQIARWGEVEDSHDVDHHDIRKQIGSAACTL Zygro1 WDQVSVIQLDKK-PVRTP-LGNHLAVDLARLLQKEWSNISHGSVKTHALPLTSLIARCIDLLRYLDTDTILVFSLRAAQDDMYLPIIGSVEKFLSLSAWDLAIFEKTVLTTKSFICGILLLTMEDIARAATLETIHQTERWGEVEDTHDVDKRDIRRNVHAAAIAA [Cluster2029.fasta_al_trimmed; alignment length = 42] Allma1 MAKSKNHTAHNQNKKAHRNGIKKVVDPKFLRNQRFARAGTLA Ashgo11 MAKSKNHTAHNQTKKAHRNGIKKPVDAKFKRNHKYALHGTAK Aspfu1 MAKSKNASQHHRSQKAHRNGIKKPVDPKFRRNHRHALHGTMK Aurde31 -----SHTNHNQNKKAHRNGIKKPVDPKFRRNQRFARAGTVR Batde5 MSKSKNHTNHNQNKKAHRNGIRKPVDAKFRRNQRYAKMGSFT Botbo1 MAKSKNHTAHNQTRKAHRNGIKAPVDSKFRKNQKFARAGTIK Botci1 MAKSKNSSQHNQSKKAHRNGIKKPTDPKFRRNHRHALHGTMK Caeel ------------------------VDAKFIKNLRFSRKNNKR Canalb1 MAKSKNHTAHNQTRKAHRNGIKKPVDAKFKRNHRYALHGTAK Cangl MAKSKNHTAHNQTRKAHRNGIKKPVDPKFRRNHRHALRGTAK Capow MSKSKNHTNHNQSVKAHRNGIKKPVDPKFLRNMRFAKKHNVL Catan2 MAKSKNHTNHNQNKKAHRNGIKKVVDPKFRRNQKFAKKGTLV Cioin MAKSKNHTNHNQNRKYHKNGIKKPVDPKYLKNMKFAKKHNKR CocheC53 MAKSKNSSQHNQSKKNHRNGIKKPTDPKFRRNHRHALHGTMR Coere1 MAKSKNHTNHNQNSKAHRNGIKKPVDPKFLRNQRFAKRGTAL Conco1 MSKSKNHTNHNQNKKAHRNGIRKPVDPKFLRNLRFAKKGSWT Conpu1 MAKSKNHTNHNQNRKAHRNGIKKPVDPKFRRNSLHALVGSRK Copci MAKSKNHTNHNQTRKAHRNGIKRPVDPKFRRNARFARVGSER Croqu1 MAKSKNHTNHNQSKKAHKNGIKKPVDPKFRRNQKFAKHGTQK CryneH991 MAKSKNHTAHNQNKKAHRNKIQRPVDPKFRRNARYAAQGSAK Crypa2 MAKSKNSSQHNQSKKAHRNGIKKPTDPKFRRNHRYALHGTMK Debha1 MSKSKNHTAHNQTKKAHRNGIKKPVDAKFRRNHRYALHGTAK Dekbr2 MSKSKNHTNHNQIKKAHRNGIKKPVDSKFRRNHRYALHGTTK Dicdi MAKSKNHSTHHKNRKDHRNGIKKAVELGFARNQRYARIGTEI Dmel MAKSKNHTNHNQNKKAHRNGIKRPMDVKFLINQRYARKGNLS Enthi MSKDKNRSSHNQSHKAHRNGFYKPMNVQVLKNTKAQRKFALA Falba MAKSKNHTSKNQSRKAHRNGIKKPVCTKFLLNQRYALQGTFR Fomme1 -----SHTNHNQSKKAHRNGIKTP----FRRNARFALVGSHR Fusgr1 MAKSKNSSQHNQSRKAHRNGIKKPTDPKFRRNHRHALHGNMK Galma1 MAKSKNHTNHNQNKKAHRNGIRKPVDAKFRRNARFALAGSNK Ganpr1 ------------------------------------------ Gloin1 MAKSKNHTNHNQNRKAHRNGIKKPVDPKFLRNQRYAKKKTIE Hisca1 MAKSKNSSQHTLNRKAHRNGIKKPTDPKFRRNHRHALHGTMK Klula1 MAKSKNHTAHNQTKKAHRNGIKKPVDAKFRRNHRFALHGTAK Lacbi2 MAKSKNHTNHNQSKKAHRNGIKKPVDAKFRRNARHALAGSNK Lenti61 MAKSKNHTNHNQIRKAHRNGIKKPVDPKFRRNSRFALVGSRK Malgl1 -----------MSRKAHRNGIKKPVDPKFMRNQRYAKHGSER Mellp23 MAKSKNHTNHNQNKKAHKNGIKRPVDSKFRRNQKFAKAGTLK Mnele MAKSKNHTNHNQNRKAHRNGIKKPMDSKFVRNLRFSKKHNTE Monbr MAKSKNHTAHNQNYKAHRNGLKKPMDPKFLRNMRFAKKGNVR Morel2 MAKSKNHTNHNQNKKAHRNGIKKVVCPKFIRNQRFAKKGSAA Mucci2 MAKSKNHTNHNQNKKAHRNGLKKPLDAKFLRNQRFAKKGTQK Mydma ------------------------------------------ Neucr2 MAKSKNSSQHNQSRKAHRNGIKKPTDPKFRRNHRHALHGTAK Orpsp11 ------------------------------------------ Pench1 MAKSKNASQHHNSQKAHRNGIKKPVDPKFRRNHRHALHGTMK Phybl2 MSKSKNHTNHNQNKKAHRNGLKKPVDAKFLRNQRHARKGTEK Picst3 MSKSKNHTAHNQTKKAHKNGIKKPVDAKFKRNHRYALHGTAK Plicr1 MAKSKNHTNHNQSYKAHRNGLRKPVDAKFRRNARHAHAGSYK Polpo MAKSKNHSTHHRNSKEHRNGIKKPLDTKFARNQRYARIGVKP Pucgr2 MAKSKNHTNHNQNKKAHKNGIHRPVDPKFRRNQKFAKHGTQK Punst1 MAKSKNHTNHNQNKKAHRNGIKKPVDPKFRRNAKFALIGSRK Rhior3 MAKSKNHTNHNQNKKAHRNGIKKALDAKFLRNQRFAKKGTQK Rhoto1 MAKSKNHTNHNQNKKAHRNGIKKPVDPKFRRNARYAAQGTQK Rozal11 MAKSKNHTNHNQNRKAHRNGIKKVVDPKFVRNQKFARRGTIR Sacce1 MAKSKNHTAHNQTRKAHRNGIKKPVDPKFRRNHKHALHGTAK Salro MAKSKNHTAHNQNYKAHKNGLKKPRDPKLVRNMRFAKKGSIR Schco3 MAKSKNHTNHNQNKKAHRNGIKRPVDAKFRRNMRYAATGSRK Schpo1 MAKSKNHTNHNQNKKAHRNGIKRPRDAKFRRNQKFANRGTVE Sorma MAKSKNSSQHNQSRKAHRNGIKKPTDPKFRRNHRHALHGTAK Sphar MAKSKNHTAHNQSAKAHRNGIKKPVDPKFKRNMRFAKKHNKK Spipu1 ------------------------------------------ Sporo1 MAKSKNHTNHNQNKKAHRNGIKKPVDPKFRRNQRYAAQGTEK Stehi1 MAKSKNHTNHNQSKKAHKNGIKKPVDAKFRRNARFASAGSYK Tapde11 ------------------------------------------ Thetr ------------------------------------------ Treme1 ------------------------------------------ Trire2 MAKSKNSSQHNQSRKAHRNGIKKPTDPKFRRNHRHALHGTMK Umbra1 MSKSKNHTNHNQNKKAHRNGIHKPVDAKFIKNQRHAKAGSLV Ustma22 MAKSKNSSQHNQVRKAHRNGIKKPVDPKFVRNQRYAKHGTEK Walse1 MAKSKNHTNHNQSAKAHRN-LKFSVDPKFLRNQRYATQGNIK Zygro1 ------------------------------------------ [Cluster2042.fasta_al_trimmed; alignment length = 253] Allma1 FVDSVKRQVQENKEKENVKQLSASKIAESDSLKKAMEIKVGETVKDVAETPIASTAVKPITDSEAYKLAKAIQDGGITSKRYRELLKRDKFKETSPVMQNLIAESDNVVSWGRFFVETETAKALTLFKQ-LDPKFTLDGFLKEAREFILPELLEAWLAGDKDTLSQWCSSVKVLTAGHDKQGLVS-DSKLIELKGVDVTSAKVLDIPVLVLSF-HTQEVILYRDRIEVRLGKPDVIYVLVMTGWTVVDAKHSG Ashgo11 FRETFKEEWKKSQEQDNIKALQGGRLGESDAYKKAREARTGETLEHAWESEILDESFEPVRQTKVYKMSEIIDDGGFMEKERRREKREQDFKEKTVVGRKLWDENENLIGLLRTISETESARVFAQFKL-LDPTFNTEEFTKHLREYIIPEVLEAYVKGDEQVLKQWFSPYNVYSAQQKQQELFA-DGRILDIRGVEIISAKLLPVPAIVVGC-RAQEIHLFRKATEIAAGHESNIYAMVLTGWKILEVRGGS Aspfu1 FRETLQAEFKASKENESTKALAAQEFAENENIKRARAAKTGQAIGKTWETPVLEKATRPVRETEAYKVKEAIDDGGWIEKEERRRQRQREFKESNPMMQKLYNESENLISTARSISENETAQVIKKFRE-MDPNFQMESFLREMREYILPEVLDAYVKGDIETLKLWLSQFHVYAALSKTAGLKS-DGRILDIRGVDVSHARMLEIPVFVVTC-RTQEVHVYRNVKELAAGMEDKVYAIGLTGWRLIEQKAAR Aurde31 FVDTLREEIRKDRELDSVKTLQVEKIQDSEAMRRAKEMKVSDAVGEMEESDIIEKTTEPIRKTEAYKIIDALDDAGYEEKEARRARRQEQVKQSNPLLRKIYDESENLVATVRGITENETAQVTRMFRD-IDPSFTMEGFGRELREYIVPEIVDAYLSADREALKLWCSTHNVLWATLEKQGLIS-DSKVLDIRNVDIVSGKILDLPVLIVQF-ATQEVLLFRKAKEIAVGAEGKVYAAVFTGWKVVEARRSA Batde5 FSESIKRQIDENKEQENVKQLGSTKIAESDAVTRAREAKVMNAVGATLDTPVSQKAAEPIANTTAAKIKEVVE-TEYKPKEVREKEKQRKFLEESTLGRTLVEQSESLMSRVRNFLESEHARTIRAFKQ-VEPTFSVDAFLKETTQYTIPELMEAFLKGDADTLKEWCSALAKLTAGFEQQGLVS-DSKLLDIRGVDIRQLKLLNVPIILIGF-TTQEILLFRNRKEIVVGSEDVIYAIAFTGWLVVDARHSS Botbo1 FVDVLRDELRKNREQDNVKQLQVDKLQDSEAMKKAKDVKVGDAVAEMEESDVISTTTEPIRKTAAYQVLDALDDGGYEEKEARRKRREDRMKETNPVLRTLYDESENFVSSIRSVTENETAQVTRILRY-MDPTFQMDSFQRELREYIVPEVVDAYLSADREALQMWCSTYNVLWATMEKQGLIS-DSKVIDIRHVEISMGKILEIPVFLVTF-HTQEVLCFRNAKEVAAGAEDRVYGAVITGWKILEARRSA Botci1 FTETLQTEFKASKENESTKQLAAHQFTENENVKRARQATTAGAVGKTWETPVLDKATQPIRQTEAYKVKNVIDDGGWVEKEERRKARERDFRDSNRVMQSLYNESENLISTARSISENETAQVIKKFRE-MDPSFQMEPFLREMREYILPEVLDAYVKGDTETLKLWLSQFSVYDALSKTAGLKS-DGRILDIRHVEVLSARMLDIPVFIITC-RTQEVHVYRNAKQLAAGMEDKVYAIGVTGWRLIEQKSGR Caeel LIDNVRDEMQKNKEQEHQQQLKMQELNESDALKDARKKELSDHMKKIQKTEAVEKVAEKVGDTEVYKMKTVKDERMYSRPEALTKRTDKNFSESNTYYHKLYDESDNAVRMMRGVTQNEVSEVLTEIHK-IDANFDKQEWLRFCETKIIPNILEAFIRFDLEVLQSWCHAYTQLSTVVKKMHFSTKDSRIIDINKVEMATGKMMEGPVLIISF-QVYMINVTKNADKVVEGDPDNPHIWVLCAWKLLEHMQET Canalb1 FFDTFKTEVKKSNEKENIKALQSGRMAESEAFKRAKEAKGAETVGDAWESPVADKAFEPVRKTQVYKMSEVIDDGGFLTKEQREALRMENFKLKSPIGRGVWEESENLIALIRTIVETEQAKVVKQLKL-MDPSFRLTDFQRTLTNYIVPEVVDAYIKNDAKVLKEWLSPYNVWEANNKQQGLFS-DSRVLDIRGVEIVTCKSLQVPVIVVSC-RAQEIHLYRKAKEIAAGTEDHIYAMVLTGWKIVEARGGS Cangl FRETFKKEWEKSQEQDNIKTLQSGRLGESEAYKKAREAKTGETVEEAWDSDILDESFEPVRQTKIYKVSEVIDDGGFITKEQRRLKREEDFKEKTPVGRTLWDESENLIVFLRKITETESARVYKQFKM-VDPTFTNIGFTKHLRDYIVPEVLEAYVKGDEKVLKKWFSPFNVYNAQQKKQELFS-DGKILDIRGVEVVSAKLLQIPVLVVGC-RAQEIHLYRKAKEIAAGDESNIYAMVFTGWKILEIRGSS Capow NLSNRLKEGFDDKEKQNVEEFQMRPIMEGKAAQQAKSIAVVDQIPT--DHPIAHNSTRPYRPPAKVKEEEA-----------------KNFKDSNPIMVKLFGESDNIIRVLSNVSPSEIGMVIGEINR-VDPNFNVDEFTIDCEKQIIPILMEAVFKSDLKALEQWCHCFRRLLEPIKALGVQL-EHKVMELNGVELRTAQLMEGPTLVFIF-NMQYTRVLRNSSEIIEGDPDQIYAMALTSWRVIDLVHER Catan2 FASSLKRQVEENKQTQNVKLLAANKLSESDSIKKARELKVAETVTEVAETPVAEAAVRPITESERYKLNTAIQAGGVTSKHYRDLIKRDHFKETSPLAQTMVAESDNVVSWGRWLVETETAKTMTLLKQ-LDPTFNLEEFMREAREFILPEVLEAWLHGDKQELARWCSSMRVLTAQHDKQGLVS-DSRLVELKQVDVAAAKVLEIPVLMLSF-TTQEVILYRDRIEVKIGKEDVIYVVVLTGWKVVDAKHAT Cioin FIETIKQEYNKDPEKESIKKFRAKELEDSDALKQARKKKIKSKVSELGSS--ISDAAKRASESEALKLSDIAQGSLYRPPTVLRMRKQESFKTSK-VGESIFDESDNLIRGSRFITGTDISKVMTEIAR-IDPEFSAQGFLDFCRFEIIPNLLEAISQGNENIVKDWCSPYNQLMFPVKQIGCRY-ELTTVDLDHVDIAGATKVDGPVLVISF-QTQQIMVVRNKKDIVEGDSDQIHVWALCAWKIIDSMSAS CocheC53 -------------------------------------------VGQTWDTMPIEYATRPVRQTKAFQVKETIDDGGWVEKEERRKRREREWKDNSKLAQGFYRESDNLIETARSISENETAMVIKKFRE-MDPNFQMESFLTEMREYILPEVLDAYVKGDVAVLKEWLSQYSVYAALMQAAGLKS-DGKIVDIRGVDVLNAKLLEIPVFILTC-RTQEVHVYRNAKELASGMDDKVYAIGVTGWRLIEQKSAR Coere1 FADSVRRQVKENQEQNNMKLLEGSKFSDSEAMKKTKEAAVGGAVGSVSESPVASTATAPIRNTDAYKVKGYVDEGGYRDKEQRTRSRIDNFKANNSVMQGIYNESENVIEATRAVTETESASALRQIRDTIDPGFNLDEFVRECREFIIPEILDAYLHSDAETLKVWCSSYNVLTAIFTQQGVVS-DCKILDMRHVEFHSARVLEVPVIIITF-QTHENNIFRNKKEIVMGSEDAIYVSIFTGWKMIDAKQAS Conco1 FRDSVKRQIKENQDNQSVKQLQSDGIKDSETLKRAKDLSVGKSVDDMNETVFLYDTTEPIRQSEAYKIETIVDDGGYRSKEARQVAKEKNFKDNSPLVQGLYDESENLVSSVRDVTESEQAKAIKQVRMTLDPNFDLENFLRELREYIVPDILDAFHSSDKITLRQWCSTFNVLNEGFKQQGLIP-DSQILDLRRVDIPAVKILEIPVFVVSF-ETQEIILFRKKTEIAFGREDHVYVMVFVGWKVMESRHSS Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci FVEVLRDELKKNREQDNVKQLQVEKFQDSEAMRKAREAKVGDAVGEMEESEIIDKSTEPIRKTAAYKLIDALDDAGFEEREARRLRRQNKLKETNPILRSFYDESEHVVSSMRSVTENETAQVTRLMKA-MDPTFNRESFERELREYIVPEVVDAYLSADQEALRQWCGTYNVLWATMEKQGFIS-DSKVLDIRQVDVMDAKILEVPVFIVSF-ATQEMLLFRNAKEIVVGAEDRVYVAVITGWKVMEGRRSA Croqu1 FMDVLKSEYAKSQAQENVRELTAQGLKDSEAAQKMREASVSDAVNRIEESRLI---GEPIRQTEVYKV-----DGGYVEKAERRRKRQSRL-ASEPILRAWYEDSDNIIASMRTVTETETAKVVRLIKE-IDPDFEFDGFLRDLREYIVPEIVDAYVDVDLKILKLWTSAYNVITAPLQKRGLRP-ENQVIDLKGIDIMSAKVLQIPVFVIAF-RTHEISCFINPGKTEVGDPDQIYVIVMTGWKVIDARRSS CryneH991 FTQVLKEEIEKNKGQDNVKQLQVDKFADSAAMKRAKDVSVHDAVQH-ADSEVASSATAPIRDTKAYKIEEAFEDGGYEEKEARRRKRELAFIKESPTYQR-YYESDSFVSVIRTIGENETAQVIRAMKA-LDPNFRMDRWTGELREYIVPEVVDAYLSADRESLKAWCGTFNVLWATMGKQGLVS-DSKILDIKHVDIAHGKMLEIPVFVITF-ATQEQLLFRSAKKVVVGSEDDVYAMVVTGWKVVEARRGA Crypa2 FMETMQTEFKASKENDSTKQLAATDFVESESVRRAREANTAGAVGKTWDTSVIDKTTKPIRDTEAFKVKSVIDDGGWVDKEERRKQREKNFKDSNKFVQGVYNESENLILTARSITENETAMVIKKFRS-MDPAFQVEPFLRELREYILPEVLDAYVKGDVETLKLWLSQYSVYEALTKQAGLKS-DGRILDIRHVDILKARMLEIPVFIITA-RTQEVHVYRNAKQLAAGMEDKVYAIGITGWRLIEQKSAR Debha1 FFDTFKAEVKKSNEKENIKALQSGRVADSEAFRKAKEAKTAHVVGGAWESPVADKAFDPVRNTTVYKVSDVIDDGGFLTKEQRQKLREENFKVKSPIGRAIWDDSENLISLVRTIIETEQAKVIKQFKQ-MDPAFRVTDFTKTLTNYIVPELLDSYIKNDEKVLKHWFSPFNVWQANNKQQGLFS-DGKILDIRGVDIVTCKSLQIPVIVVSC-RAQEIHLYRKAKEIAAGTEDHIYAMVFTGWKVIEARGGS Dekbr2 FVDTFRKEWKKSTENDQIKQLKTDEMGDSEAFKKAREAKAAEAVGGAWDSPVADKVIEPVRKTKAYKAKEAYDEGSYETKEQRRKRREKS-APNSPLKKASWEEADNLLVLIRNIGETENAKVVKAFQQ-MDPNFTVTKFNKKLREYIVPEVLDAYESGDQKTLKKWLSPFNIIMTQQKQQGVIN-DGRILDIRNVSVVAYKILETPVLVTGS-RVQEIVSFRNAKAVVAGSDEDIYAMVLTGWRVLEVKGGS Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel FFDNMKAEMDKNKEKDNIRKFRAQKLEESDALKSARQKAIKERVGDASKSHLISDTSGKLGQTSAFQTTTIKKERVYRAPAKLRKRVQENFKNNNTYVNKVYDESENVIRASRLLTKTELSETMTELVK-IDPSFDQKDFLRDCETDIIPNILESIVRGDLEILKDWCFTFNIIANPIKKAGVYL-DSKILDIENIELAMGKVMEGPVLIITF-QAQQIMCVRDQKQVVEGDPEKVYVWVLCAWRLMESANSS Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -ASPNPKAAVEEIPDMSPEEVARFKAAAEARAAKAAAEAEAAEAAKAKAAETAAAAAKPSATPTGAGTESTATRPPHEEEEEDDDEDDQQYREATSVTVSRVKAWSNLFKGVGSFSGNEMSEVLTRLQE-LDPEFSEEKWMRYVQTYVIPEVMEAASENRADDIRMWCSTAGILLSERENRNILM-DRQVHELRSLDIIDAGFVENPVLTISFRTFETIQ-LRDATEAIQDETSGIYQISLLGWIVQDMQGAM Fomme1 FVDTLREELQKNREQANVKQLQVDKLQDSEAMKRARAAKVGDAVSEMEESDIIASTTEPIRNTEAYKVMDALDDAGYEEKEARRQRRANRMKETNPVFRQFYDESENIISSMRSVTETEYAQVIRQMRY-MDPTFDRESFERELREYIVPEIVDAYLSADRESLQKWCGTYNLLWATMERQGLIS-DSKVLDIRQVDIASARLLEVPVFVVSF-ATQEVLLFRNAKEVVVGAENKVYAAVLTGWKVIEARRSS Fusgr1 FMETMNTEFQKSQENESTKQIAANQFAESEGVRRAREAATAGAIGKTWDTSVVDKATQPIRNTEAYKVKDVIDDGGWVEKEERRKRRERDFRDQNKYVQGLYDESENLVSTARSITENETAMVIKKFRS-MDPGFQTEPFLQELREYILPEVLDAYVKGETETLKLWLSQYSVYEALTKQAGMKS-DGKILDIRNVDILRARMLDVPVFIVTC-RTQEVHVYRNAKELAAGMEDKVYAIGITGWRLIEQKSGR Galma1 FVDVLKDELRKNREQENVKQLQVDKLQDSEAMKRARAAKVGDAVSEMEESEVVEKSTEPIRNTAAYKVIDALDDAGFEEKEARRRRRQNKLKETNTVLRTFYDESEHVVSSMRSVTENETAQVMRLMKS-MDPTFSREHFERELREYIVPEVVDAYLSADQESLKEWCGTYNVLWATMEKQGLIS-ESKVLDIRQVDVADAKILEVPIFLITF-ATQEMMVFRNAREVALGAENKVYVAAVTGWKVVEARRSA Ganpr1 FRESIRRQVQENKEQEGVKQLNTNQLAESDAFQRAKQAKVVEA---VLESDAVIKVAEPIVDNPATRAQAIHQSTELKSAQERES---EEWKESNPLAKAWVEESDHLVERLRDFAESETARVVKRFRQ-VDPNFRTDRWLVQAQKWIIPEIMEAYLKGNDAKLKEWCGTYNVLTAGLKEQGLVS-GCRLLDLRNVDLLSAKLIDLPVLVVSF-QTQEVLVFRNRKEIKVGREDHIYAAVFTGWRMIDAKHSA Gloin1 FFETINEEIKKNKEQQNVKLLQAGQLSESDALRKAKEAKVGSAVSDVNETPFVSTTTEPIRQTRVYTLKETVGDGGFVDKETRKKMKENKIKETNPIIQGIYEDSDNFISYTRAFTENETAQVMTQMKM-IDPRFNLEDFMREAREYIIPEIMEAYLKGDTTTLREWCSTYNVLTHGIKKQGLIS-DSRILDIRDVEFVTAKLLEIPVLVISF-NTQEVIVFRDRLEIKYGSEDQIYGCVFTGWKMIDAKNRS Hisca1 FTETLRSEFKASKENESTKALAAHQFTESESVKRARAATTGKVIGQTWDTSVIEMATRPVRETAAYKVKEAIDDGGWMEKEERRKQREKEFKDSSRLMQSYYNESDNLVTTLRGISENETAMVIKKFRE-MDPSFQIEPFLRELREYMLPEVLDAYVKGDVETLKLWLSQYNVYAALAQTAGLKS-DGRILDIRHVDISHARMLEIPVFIITC-RTQEVHVYRNVKELAAGMEDKVYAIGMTGWRMIEQKSGR Klula1 FRETFKQEWEKSKEQDNIKALQSGKLGESEAYKKAREAKTGETVETAWDSEILDESFEPVRKTKVYKVSEVIDDGGFITKEQRRLMKEEDFKEKTPVGRKLWDESENLVVMLRTVSETESARVYGQFKM-MDPTFNTEDFTKHLREYIIPEILEAYVKGDEAVLKQWFSPYNVYAAQQKEQELFA-DGKILDIRGVEIVSAKLLPIPVLVVGC-RAQEIHLYRKAKEIAAGAESSIYAMVFTGWKILEVRGGS Lacbi2 FVDVLRDELRKNQEQDNVKQLQVDKFQDSEAMKRARAAKVGDAVTEMEESEVIEKSTEPIRNTAAYKVVDALDDAGFEEKEARRLRRQNKLKETNPVLRSLYDQSENVVSSMRSVTENETAQVMRMMKV-LDPAFNREGFERELREYIVPEVVDAYLSADQEALKAWCGTYNVLWATMERQGLIS-DSKVLDIRQVDVSDGKILEIPVFVISF-ATQEVLLFRNAKEIMVGADNKVYVAVVTGWKVIEARRSA Lenti61 FVEVLRDELRKNREQDNVKQLQVEKFQDSEAMKRAREAKVGDAVGEMEESEIIEKTTEPIRNTAAYKISDALDDAGFEEKEARRKRRQNQLKETNPLFRQFYDESENLISSMRSVTENESAQVQRLMKA-MDPTFNMESFERELREYIVPEVVDAYLSADREALQAWCGTYNVLWATMEKQGLVS-DSKILDIRQVDVSTGKILEIPVFVITF-ATQEMLLFRNAKEIVVGSEDRVYAAVITGWKIVEGRRSA Malgl1 FVETLRQELTKSREQDNIKQLQSAKFQDTETMRKAREAQVSSAIGTMEESELIEDSTAPVRNTEVYKINEAFDDHGTSAADARRLKRESRFAQESPIMRRLYQDSEHFIERLRGVTENETAQVVRAIKQ-LDPSFTLSGFTIDLREYVVPEVLDAYHTAQRHLLRQWCGTYNVLMATLDQRGYIA-DGRILDLSNIEIVQGKILEMPVLVISF-QTQELMYFTDPKEIIDGSVEQAYAMVLTGWKIIEARRGQ Mellp23 FMDVLKSEYAKSQAQENVRELTAQGLKDSEAAQKMREASVSDAVNKIEDSRLI---GEPIRQTEVYKV-----DGGYIEKAERRRKRQSRL-ASEPILKAWYEDSDNVIASMRTVTETETAKVVRLIKE-IDRDFEFDGFLRDLREYIVPEIVDAYVDADLKVLKLWTSAYNVITAPMQQRGLRP-ENQVIDLKGIDIMSAKVLQLPVFVIAF-RTHEINCFTNPGKVEVGNPDQIYVIVMTGWKVIDARRSS Mnele SYDKMRQWREKSKQQSKIKDLYSG-IADNPLYQKAKAQEMGKKVEEMEKSKILAKETEDLQSSEKFKTQETLKTEIYRSPEQLKKRIKKNFKEQNPLVQKLLEESDNFARAGYKVFPGEISATTAEIHK-IDPNFDLTLFSATLRLEIVPNVLEAYLRSDIEILENWCQALGQFKHMLAFSGTIN----LIDIGECDILSGCMLEGPVFMFNV-ATQQHFVKTEKVEAAEIVEDSIYMIAVCAWTVLEVEHVV Monbr ATGTGAADARPNREDDELDRLL--AEEEERALAHARPA--------------RSQVGGPIGQ--LIKKDQVTEDKAYQAPVDRRRSSINSFKENNPVLNRIYDESDNLVRGARSVTNDESGAVLAEVQR-LDPTFDRLAFTLHCEKKVIPAVLEAFIAGDKEVLKEWCACFNNMAAQIDASGIIY-EARILDIADVEYITAQRMDGPVLVFVF-NAQQTHCIRDRTAVVEGSEDNIYMFAMRAWQVLELVNST Morel2 FVETLKEQIKKNKEQESVKKLQSGKAGDSDALKKAKDAKLGETVSEAAENEFVDSSTKPIRDNEYFKAETLIQDGGYISKAERRRARGSKFKDTNPVMQSVYEDSDNFVAWARVVTETENAKTIRALQM-IDPRFKMDNFMKEAREFIIPEIMDAVLNADSETLNEWCSTYNVLTAGFQAQGLVS-DCKILELRNVELVSAKVLEVPVLIISF-NTQEVTVFRNRLEVVFGKEDAIYACVITGVRIMDAKHGS Mucci2 -------------------------LN-----------KVGSSVNEASETEFINKTADPLKKSETVGFKTVLKDGGFVDKETRRKMRETKFKEDSPIMQGIYEESDNFVSYSRAFTESDQAQAIRAFQA-IDPTFNMDKFMTDARKYIVPELMEAYLKGDVETLKLWCSTYNVLTAVIQQQGLIS-DCKIQDLRDIDLVAAKILEVPVLVLSF-RTQEIIVFRNAKEIVYGKEDLIYACVLTGWRIIDAKHDS Mydma FIENIQEGLKRDKQQENLKKFKAKKFDESDAIKEAKLKTVSKTVEKATKSEIISKHSEEIEKNETFKFSKVKEDRPYQRPEHLKRRTQKNFRDNNPVVTGLYDESDNIIRATRVVTQSEQAATIAEITK-IDPSFNKDKFIKECEFEIIPTVLEAYLRGDIECLQDWCHVFSILSTQIKAQGLVN-ESRILDIRDVDLVMAKIMEGPVLILTF-QAQQVSIMKDSKKIIEGGEDNIYVWAMCAWRVLEGIQQA Neucr2 FMETMQTEFKQSQENESTKALAANQIAESEAIRRARQATTATAVGKTWETPVLDKATKPIRETEAYKVKDVIDDGGWAEKEERRKRRERDFRDSNKFVQNVYEESENLISTARSITENETAQVIKKLRE-LDPGFNMENFLMELREYILPEVLEAYVKGDVETLKLWLSQYSVYEALTKQAGLKS-DGRILDIRGVDVLKARMLEIPVFVITC-RTQEVHVYKNAKKLAAGMEDKVYAIGITGWRLIEQKSGR Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 FRETLQSEFKASKEEESTKALAAHQFTENENVRRARAATTGQVIGKTWNTPVLEKATRPVRETEAYKVKEAIDDGGWVEKEERRKQRQKDFKDSNPMMQKLYNESENLISTARSISENETAMVIKKFRE-IDPNFQMEPFLREMRDYMLPEVLDAYVKGDVETLKLWLSQFHVYAALAKTAGLKS-DGRILDIRGVDISHARILDIPVFVVTC-RTQEIHVYRKIKELAAGTDDKVYAIGLTGWRLIEQKAAR Phybl2 FIQTIKDQMKKNKEQDGVKTLQSGKIGESDTLKKARELKVGESINEAADTDFIDKAADPLRNSAAAGFQTVVKDAGFVDKETRRKLRESKFKEDSPIMQGIYEDSDNFVSYSRAFTESDQAQAIRAFQT-IDPTFNMEKFMTEARSYIVPELMEAYLKGDVETLKLWCSTYNVLTALIQQQGLVS-DCRIQDLRDVDLVTAKILEVPVLVLSF-RTQEIIVFRNAKEVVFGKEDHIYACVLTGWRIIDAKHDS Picst3 FFDTFKNEVKKSNEKENIKALQSGRMAESEAFKKAREALTADVVGGAWDSPVADKAFEPVRQTQVYKVSEVIDDGGFLTKEQRQRLREEEYKLKTPVGRFFWQDSENLISLIRTIIETEQAKVVKQFRM-MDPSFRLTDFQKTLTNYIVPEILDAYIKNDETVLKQWFSPFNVWQANNKQQGLFL-DGRILDIRGVEVVTCKQLQTPVIVVSC-RAQEVHLYRKAKDIAAGTEDHIYAMVLTGWKIIEARGGS Plicr1 FVDVLKEELQKNREQDNVKQLQVDKLQDSEAMKRARAAKVGDAVGEMEESEVIASTTEPIRNTTAYKLVDALDDAGFEEKEERRRRRQNRLKESNPLLRKLFDESENVVASVRGVTENETAQVMRAMKA-LDPGFSAESFERELREYIVPEVVDAYLSADREALRKWCGTYNVLWATMERQGLIS-DSKCLDIRQVDVSAGKLLETPVFIITF-STQEVLLFRNAKAVVVGAEDRVYVAALTGWKVIENVSSC Polpo FFQNYKSLINETPERKNIDDFKKPPVTDADQQQKNNEGQQQQTTTDQQQQ--QQQQQGQQQEQKKYSLRDKYKE--YKDYEKRQKEADDMYKDSAPTEEELYWKIQNLVKVTEYLPSDPTTKFYMDYKDILLPGFELTKFLEISKQIFIPEFLKLFLVGNVEEMDTYCSGLKIVSGFIKEGHKVL-DGQLLSLENFEFQGIRQTEELLFVFRM-HVISTHCIRDYLNIVQG-----------------GPHSE Pucgr2 FMDVLKSEYAKSQEQENVRELTAQGIKDSEAAQKMRKASVSEAVNKIEESRLI---AEPIRQTEVYKV-----DGGYIEKEERIRRRQSRMKGTSGLREIWYAESENVVASIRSVTETETAKVIRLVKE-VDPAFNYDAFLADLREFIIPDFVDSFVDNDLQALKMWTSAFNVTSAPMKQRGLRP-ANQIIDLKGIDILSAKVLELPVFIVAF-KTHEINCYINPATVEVGSREEIYVVVLTGWKIIDARRSS Punst1 FVDVLKDELKKNREQENVKQLQVDKLQDSEAMKRAREMKVGDAVGEMEESELIEKTTEPIRNTAAYKIVDALDDAGFEEKEARRKRRQQRLKETNPLLIKLFDESENFVTSVRGITENETAQVIRMMKA-MDSTWTMDVFEKELREYIIPEVVDAYLSADRESLQKWCSTYNVLWATMERQGLIS-DSKVLDIRQVDVTAGKLLEVPVWVVTF-ATQEVMTFRNAKEIVVGAEDKVYAAVITGWKVIEARRSA Rhior3 FMDTLKDQMKKDKD---IKTLQTGRLNDSEALKKAKEMKVGSQVNEASETEFINKSAEPIKKSAAVGLKTVVKDSGFVDKETRRKMRETKFKEDSPIMQGIYEESDNFISYTRAFTESDQAQAIRAFQG-IDPTFNMDKFMIDARTYIVPELMEAYLKGDVDTLKLWCSTYNVLTAVIQQQGLIS-DCKIQDLRDIELVAAKILEVPVLVLSF-RTQEIIVFRNAKEIVYGKEDLIYACVLTGWRIIDAKHDS Rhoto1 FIDVFRDELRKNREQDSVKQLGVSKVQDSEAMQRAKAMNVNDAVSTMEETALAYTASAPIRDTEAYKITDLLDNGGYIDRDARRRRRESRLPK--PLADALYAESDNFIVMSRSVTETETAKVTKWVKE-MDPSFTQESFLRELREYIVPELVDAYVNADQPILKQWCSTFNVLVATLQGPSLVS-ESRVLDIRNVDIMSAKILEVHVFVVAW-RTQEVLAYRDIKEVTVGDENKIYVAVLTGWKVIDARRAA Rozal11 FIEEVKKEANKDQEQKGVKKLEIIVVKKSKFAERARAIKVTSKIGEITES--TLETLKKVVDNPVVNLSTAKDVGGFYKKEYRDKIRGDDFSNNNSIIRSAFDESNNLVYHARNLVKSETGKVTRVLMD-RDPSFSIDSFLKEATEFILPEIIESYVNCDKDALKPWLF------------GLFI-EGKVLDMREIEINKLLMVDEPVITITA-HVQQVSFYRNKNEIVEGKE---------SLHLFE----- Sacce1 FRDTFKKEWEKSQEQENIKTLQSGKLGESEAYKKAREAKTGETMEHAWESELLDESFEPVRQTKIYKVSEVIDDGGFITKEQRRLKREEDFKEKTVVGRSIWDESENLIVVMRKITETESSRVYSQFKL-MDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSPFNVYAAQQKEQDVYA-DGRILDIRGVEIVSAKLLAIPVLVVGC-RAQEINLYRKKKEIAAGDEANIYAMVFTGWKILEVRGGS Salro AAQHAAKAAKDKKEQEEQQQ-----QQQQQASSLASGA--------------KEELRGPIRK--LVDKSQVTEDKPYQAPVDRRRSSI------------------------------------------------------------------------------------------------------------------------------------------------------------------TQT Schco3 FVDVLKDELRKNREQDNVKQLQVDKFQDSEAMKRARDASVGDAVGEMEESEVIEKSTEPIRNTAAYKLVDALDDAGFEEKEARRLRRKNRLKEENPVLRSFYDESENVVSTMRSVTETEQAQVLRMMKA-IDPTFDREQFERELREYIVPEVVDAYLSADQKALKDWCSTYNVLWATMEKQGLVS-ESKVLDIRQVDISDGKILDIPVYLVQF-ATQEVLLFRNIKEVAVGAEDKVYAAAITGWKIIEARRSA Schpo1 FMDTFRAELKKSQEQDSVKALQSGSLSESDTFKKARDAKAGAKIGSAWESAPVDTATKPVRETAFYKIKQTMSDGFYADKEQRKKLREEQIKNESRLVRKIYQESEHIVSSIRDMAETEASQVMRRFKE-IDPSFNTEHFLQYLREYIVPEVTEAYVKGDKEVLKTWLSPFSVYETTTKKHGVVS-VGKILDIRGVDIMSQRLLQIPVFIVTF-RTQEVHMFKDASELVAGKDDRIYASVFTGWRIVDARARA Sorma FMETMQTEFKQSQENESTKALAANQIAESEAIRRARQATTATAVGKTWETPVLDKATKPIRETEAYKVKEVIDDGGWAEKEERRKRRERDFRDSNKVVQNIYEESENLISTARSITENETAQVIKKLRE-VDPGFNMENFLMELREYILPEVLEAYVKGDVQTLKLWLSQYSVYEALTKTAGLKS-DGRILDIRGVDVLKARMLDIPVFVITC-RTQEVHVYKNAKKLAAGMEDKVYAIGITGWRLIEQKSGR Sphar FLNSIKKGAEETAPSTPTTESVSSKMSSKKGQQNAKKVKVKDNLGQLGATKFTQQIGAEFSNSDAAHRSELLEGKPYQKPSVADRERIKEFKDNNPITNRAYDESDNFVRSMRSITESEMITVLREICK-QDPDFEREEFIEHAHKSLIPVLLESYFNQDLQTLEAWCSTYNVLASNIKDAGHTV-DVKILDIRDVDIFNAMMMEGPVLTVTC-MVQQITVEKDKAKVVDGDPDAIYAFAFCAWRVMDMRRST Spipu1 FYKSVQRQVKENREQQNVQQLSTKELAESDAVQRAKEAKVIEKVGDVLENPVSSKVAKPVLDTQAAKLKVVHKDHEYVPREVRER---RKFKEDSPIAQKLFDESDHVVERVRDFFETETAQVVRALKA-VDPGFRTERFLKEATMYYIPEIVEAYLKGEAAILREWCSAYARLAAGFESQGLVS-DCKLLDLRRVDIRKLTLLEVPVILVTF-QTDEILMFRNVKKLVVGNENAIYVMAFTGWVVIDSR-ST Sporo1 FVEVLREEVRKNREQDSVKQLGVGKVQDSEAMKRAKEASINDAVGTMEETAFAFQASAPVRDTEAYKITDLLENGGYIDREARRKRRASRLPK--PMADAMYAESDNFIVMSRSVTETETAKVTKWVKE-LDPSFTQESFLKELREYIVPELVDAYVNGDQPTLKQWCSTFNVLVATLGGPAMMS-ESRVLDIRNLDIMSAKILELHVFVVSW-RTQEVLAYRDLKEIAVGDENKIYVAVLTGWKVIDPKRAP Stehi1 FVEVLKDELKKNREQDNVKQLQVDKFQDSEAMKKAKAAKVGDAVGEMEESDLIASTTEPIRNTAAYKLVDALDDAGFEEKEARRKRRAQQIKETNPVLRYFYQDSEHVVSSMRSVTENETAQVMRMMKA-LDPTFTMEGFERELREYIVPEVVDAYLSADQESLRAWCGTYNVLWATMERQGLVS-DSKVLDIRQVDVSSGKILDVPVFVITF-ATQEVLMFKNAKEVVVGAENRVYAAVITGWKVIEARRSA Tapde11 FVDTFKSELKKSQEQDSVKALQAEKAGESDAYKKAREAKTGEVLGSAWESPVLDKTTKPLRESEAFKISSTIDDGGFSTPEARKAAREKSYKEQSSIFAGLYSESENIVSSTREITENESARVIRLMKE-IDPSFRVEPWLNQLRDYILPEICEAYIKNDTPVLAQWLSPLSVHTATSKEQKLIS-DGKIVDLRNVDIAQYKVVPIPVFIVSF-RTQEIHLYRNA-DVVAGREDHVYIAIFTGWRVMDARGQP Thetr FVNKVKSGLAEDKEQKNLEALDKKRLAEKKSLKKAAATAAAAKAKGASESSVVSSQAKTAASSETASTRKMAEKPRYEAELSE-----NRYRDN-----SAVRESDNLVSARGAYYETEAAMCYSEIRR-LDPGFDEYALQARLEKYTLPEVMEALGRHDLAELKNLVSTLPPASASRR-----Y-DTHILHISPLEMIAIKPIEEPTLFYSF-TVQQVQVVRDA-NVIEGDPDSIYIWSVQVWQLVGALDPE Treme1 FIETLKQEIKANQGQDNVKQLQVDKLADTQAMRRAKELSASEAISR-EDSGVTARLTQPFRDTPMYKIEEAFDDGGYEEKEERRKRREFSFLTSSPTFQR-YYESDSAVSALRYVTENETARVIRAMRE-IDPDFQLESWTRELREYIVPEVVDAYLSADRESLKAWCGTYNVLWATMGKQGLIS-DSKILDIKHVDVTEGKMLEIPVFIITF-ATQELLLFRNAKDVVVGSENDVYALVITGWKVVEARRGT Trire2 FMETMNTELQKSQENESTKQIAASQLAESESVRRAREATTATAIGKTWETPVVDKATKPIRETEAFKVKNVIDDGGWVEKEERRKRRERDFRDSNKFVQNVYEESENLITTARSITENETAMVIKKFRS-MDPSFRTEPFLQELREYILPEVLDAYVKGDTEVLKQWLSQFSVYEALTKQAGMKS-DGRILDIRNVDILKARMLDIPVFIITC-RTQEVHVYRNAKELAAGMEDRVYAIGITGWRLIEQKSGR Umbra1 FVETIKDQVKKNKDQQGVKSLQSGKVYDSEALKKARELKVGSTVNKASEAEFINKAADPLKKNPVVGFQTVLKDGGFVDKETRRKLRENKFKEDSSFMQGIYEDSDNFVSYTRAFTESDQAQAIKAFQQ-VDRTFNLEKFMKEAREYIVPELMDAYLKGDTETLKMWCSTYNVLTAVAQQQGLIS-DCKIQDLRDVDLVTAKILDIPVLVLSF-RTQEVVLFRNAIEIVFGKEDHIYACVLTGWRVIDAKHDS Ustma22 FVETLKAELRKNQEQENMRQLSVGKMQDSETMKKMRDAQVGDAVGAMEESELLEDSTAPIRNTEAYKLTEAFDDADKDAAEVRRIKRETNFKTSNPVFRKLYNESENLVERVRSVTENDFARVTRQMKM-LDPSFTMESFQRDLREYVVPELIDAYHGAARHLLRQWCGTFNLLMATIDSKGYIP-HGRLLDLKNVEILQAKILDVPVLVVSF-TSQELMFFKDPKEVKAGNDSQPYAIVLTGWKVVEARRGQ Walse1 FVNVLREELRKNAEQENYKQLSAGKVQDSEAMQRAREVKVSEGVGEIENSEAVSSATQPIRDTEAYKISDALDDGGYEDKEARRLRRQQEYKDNSPLFQRMYHESESTVLTLRSVTENETARVTRAFKA-LDPDFTQDNFLVELREYIVPEVVDAYLNADKDALRRWCGTYNVLWASMESKGLIS-DSKVLDIRSVEVSKGQMLDVPVWLVIF-HTQEILLFRDAKKPVVGTEDGVYVGVFTGWKVIEARRGQ Zygro1 FRDTFKKEWEKSQEQENIKTLQSGRLGDSEGVKRAREAKTGETVEGAWESEILDKSFEPVRNTKIYKVSEVMEDGGFLTKEQRKIKREEDFREKTFIGRAIWNENENLIVILRKITETETAKVIGQFKL-LDPSFTSEGFTRQLRDYVIPEVLEAYAKGDEKTLKKWFSPFNVYAAQQKDQKLFA-DSRILDIRGVDIVSAKLLPIPVLIVGC-RAQEIQLYRSIKEVAAGHESNIYAMVFTGWRIIEVRGGS [Cluster2046.fasta_al_trimmed; alignment length = 201] Allma1 MAGSGKTSVMPYIVNLDPAVVPYAPNIDIRDTVKYAEVMKQYQLGPNGAILTSLNLFTTKFDQVLDLLEKRILIDTPGQIEVFTWSASGSIITDSLAATYPTVVAFVVDTPRSPATFMSNMLYACSILYRTRLPFVVLFNKSDVFAIEWMRDFEAFQSALLVQSMSLVLDEFYSILVSFSAVTGLGAPALFEAFYKPELER Ashgo11 MAGSGKTTFMPYVINLDPAVVPYGANIDIRDSIKYKKVMSNYNLGPNGAIVTSLNLFSTKIDQVIGLVEKKCIVDTPGQIECFVWSASGSIITESFASTFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPMVVVFNKTDVFAKEWMTDFEAFQEALLINSMSLVLEEFYSQLVGVSSFTGEGVSDFLRAVYKAEYQR Aspfu1 MAGSGKTTFMPYVLNLDPAVVPFESNIDIRDSINYKEVMKQYNLGPNGGILTSLNLFATKVDQIISLLEKRILVDTPGQIEVFVWSASGSILLETLASSFPTVIAYVIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFDAFQQALLLNSMSLMLEEFYRHLVGVSSMTGDGIDEFFQAVYKPELER Aurde31 MAGSGKTTFVPYIINLDPAVMPFEANIDIRDTVDYAQVMKQYRLGPNGGIMTSLNLFTTKFDQVLSLVENRVVLDTPGQIEIFTWSASGAIITDAVASGFPTVVAYIMDTPRAPATFMSNMLYACSILYKTRLPLLIVFNKTDAFAVEWMRDFEAFQKALLMNSMSLVLDEFYSHLVGVSSLTGDGIPAFFDAVYLPELER Batde5 MAGTGKTTLLRYAINLDPAVVPFGAHIDIRDTVNYKQVMKQYNLGPNGGILTALNLFTTKFDQVLDLVAKRILIDTPGQIEIFTWSASGAIITDTLSSTYPTVILYIIDTPRAPATFMSNMLYACSILYKTRLPFVLVFNKIDVFAKEWMTDFESFQAALLIGSMCMVLEEFYSNLVGVSSVTGEGMEELFEAVFKPELER Botbo1 MAGSGKTTFVPYIVNLDPAVMPFDANIDIRETVNYEEVMKQYNLGPNGGILTALNLFTTKFDQVLSFIEQRVILDTPGQIEIFTWSASGAIITDAVASALPTVVAYIIDTPRAPATFMSNMLYACSILYKTRLPFILVFNKTDVFAIEWMQDFEAFQAALLMNSMSLVLDEFYKHLVGVSAVTGDGIPEFFEAVYRPEIDR Botci1 MAGSGKTTFMPYVLNLDPAVVPFESNIDIRDSVNYQEVMKSYNLGPNGGILTSLNLFATKIDQILTVLEKRILVDTPGQIEVFVWSASGSILLDSLASTFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFESFQAALLLNSMSLMLEEFYSHLVGVSSMTGAGIDEFFEAVYKPELER Caeel MAGSGKTTFVPYVINLDPAVVPYPVNVDIRDTVKYKEVMKEFGMGPNGAIMTCLNLMCTRFDKVIELINKRCLLDTPGQIEAFTWSASGSIITDSLASSHPTVVMYIVDSARNPTTFMSNMLYACSILYRTKLPFIVVFNKADIFALKWMQDFERFDEALLSRSLSLVLDEFYCGLVCVSSATGEGFEDVMTAIYVPMYEK Canalb1 MAGSGKTTFVPYLINLDPAVIPFGANIDIRDSVKYKKVMEQYNLGPNGAIVTSLNLFSTKIDQVIKLIDKKVVIDTPGQIECFIWSASGSIITESFASEFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPMIVVFNKTDVFAKEWMTDFESFQMAILINSMSLMLEEFYSNLVGVSSYTGQGFDKFMEAVYKAEKER Cangl MAGSGKTTFMPYVINLDPAVVPYGANIDIRDSIKYKKVMENYQLGPNGAIVTSLNLFSTKIDQVIKLVEKKCIIDTPGQIECFVWSASGSIITESFASTFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPMIIVFNKTDVFAKEWMTDFEAFQQAVLVNSMSLMLEEFYSTLVGVSSFTGEGFDDFLDAVYKAERER Capow MAGAGKSMVMTYGINLDPAVLSFPANIDIRDTIHYKKLMEEHNLGPNGAIVLSLNLFTTQFDQLSNLLAQRVLIDTPGQIEIFTWSAGGAIICDALASRLPTCVVYVVDTVRNPVTFMSNMLYTCSILYKTQLPFVVVFNKTDIFAVEWMRDFEAFEEAVLARSLSLVLDEFYSNLVGISAARGDGMNDLVEAIYRPKLEQ Catan2 MAGSGKTTVMPYIVNLDPAVLPYTPNIDIRDTVQYPEVMKQYQLGPNGAILTSLNLFTTKFDQVLGLLDKRILIDTPGQIEAFTWSASGSIITEALAASYPTVVLFVVDTPRNPATFMSNMLYACSILYRTRLPFIVLFNKADVFAIDWMKDYDAFQTALFVQSMSLVLDEFYSILVKFSAVTGLGSQELLVALYKPELER Cioin MAGSGKTTLVPYVINLDPAVVPFPVNIDIQDTVNYKEVMKQYGLGPNGGIMTALNLFTTKFDQVLSLLQKRIVIDTPGQIEVFTWSASGAIITESLASSFPTVVVYIVDTARNPVTFMSNMLYACSILYKTKLPFFVVMNKTDIFALQWTSDFEAFEEALLTRSMSLVLDEFYNKLVGFSALTGAGMEDFLKAVYKPAYEK CocheC53 MAGSGKTTFMPYIINLDPAVVPFTPNIDIRDSVNYKEVMKQFNLGPNGGILTSLNLFSTKIDQVIGLLEKRILVDTPGQIEVFVWSASGEILLSSLASTFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDAFAKDWMTDFEAFQTALLLNSMSLVLEEFYKHLVGVSAMTGEGMDEFFKGVYKPELER Coere1 MAGSGKTTLMPYIVNLDPAVVPFQANIDIRDTVDYKQVMTEYNLGPNGGILTSLNLFTTKLDQVMDIVDKRFLYDTPGQIEIFTWSASGAIISNTLAATRPTVVVYVVDTPRSPATFMSNMMYACSILYKTQLPFVLAFNKTDVFALRWMEDFEQFQQALLIHSMSLVLDEFYNNLVGVSAMTGQGMDEFFKKIFKPTLQR Conco1 MAGSGKTTFNPYIINLDPAVVPYKPNLDIRDTVNYKTVMKEYGLGPNGAILTSLNLFTTKFEQVLDIVQKKILIDTPGQIEIFTWSASGAIITESLALSYPTVIAYIIDTPRSPATFMSNMLYACSILYKTRLPFILVFNKTDVFAVDWMQDFQKFQADIFMYSMSLVLDEFYQHLVGVSSVTGSGMDDFMKAVYKQDLLE Conpu1 MAGAGKSTFVPYILNLDPAVLPFEANIDIRDTVNYAEVMKQYNLGPNGGILTALNLFTTKFDQVLELVEKRIILDTPGQIEIFTWSASGAIITDAIASSFPTVIAYIIDTARAPATFMSNMLYACSIMYKTKLPFVLVFNKTDVFALDWMADFEAFQAALLMNSMSLVLDEFYKHLVGVSSMTGAGVKEFFDAVYLPELER Copci MAGAGKSTFVPYILNLDPAVVPYEANIDIRDTVNYQEVMKQYNLGPNGGIMTALNLFTTKFDQVLDLVEKRVILDTPGQIEIFTWSASGSIITDAVASSLPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFVLVFNKTDVFALDWMTDFEAFQLALLMNSMSLVLDEFYKNLVGVSSVTGDGVKEFFEAVYLPELER Croqu1 MAGSGKTTFVPYILNLDPAVLPFQANIDIRDTVDYKEVMKQYRLGPNGGILTALNLFTTKFDQVLHYVEKRILVDTPGQIEIFTWSASGAIITDAIASSLPTVVAYVIDTPRAPATFMSNMLYACSILYKTRLPFLLVFNKTDVFALEWMSDFESFQQALLMNSMSLVLDEFYKNLVGCSAMTGFGMKEFFEAVYRPELLR CryneH991 MAGSGKTTLMPYILNLDPAVMPYSANIDIRDTVDYKEVMKQYKLGPNGGILTALNLFTTKFDQVLGYVEKRILVDTPGQIEIFTWSASGAIITDAIASSLPTVVAYIVDTPRSPVTFMSNMLYACSILYKTKLPFIIVFNKTDVFALDWMTDFEKYQEALLMSSMNLVLEEFYNNLVGVSAMTGEGMKAFFSAVYKPELDR Crypa2 MAGSGKTTFMPYVINLDPAVVPFDSNIDIRDSVNYKEVMKQYNLGPNGGILTSLNLFATKVDQILGLLEKRILVDTPGQIEVFVWSASGTILLESLASSFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFEAFQAALLLNSMSLMLEEFYAHLVGVSSMTGQGVNEFFEAVYQPELDR Debha1 MAGSGKTTFMPYVINLDPAVVPFGANIDIRDSVKYKKVMEEYNLGPNGAIVTSLNLFATKIDQVIKLVEKRVIIDTPGQIECFIWSASGAIITEAFASTFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPMIIVFNKSDVFAKEWMQDFETFQRALLVNSMSLMLEEFYSQLVGVSSYTGEGFDEFLGAVYKAERER Dekbr2 MAGSGKTTFMPYVINLDPAVVPFGCNIDIRDSINYKKVMETYNLGPNGAIVTSLNLFATKIDQVLGSVDKRCIIDTPGQIECFVWSASGTIVTESFASEFPTILAYIIDTPRSPTTFMSNMLYACSILYKTKLPMILVFNKTDVFAKKWMTDFEAFQAALLVNSMSLVLEEFYSTLVSCSAYTGEGFDDFLKAVYVKERER Dicdi MAGSGKTTLLGYIINLDPAVLPYTPNIDIRDTVNYKEVMKQFNLGPNGGIVTSLNLFSTKFDKVLEIVEKRIILDTPGQIEVFTWSASGTIITELMASSFPTVLVYVVDTPRDPTTFMSNMLYACSIMYKSKLPMVVAFNKIDIFAEEWMSDFDSFQDALLTRSLSLVLEEFYSTLVGVSAVDGSGIDEFFEKIYKADLEK Dmel MAGSGKTTFTPYVVNLDPACVPYAAHVDIRDTVNYREVMKQYQLGPNGGIVTALNMFTTKMAQFAELVRRACVIDTPGQIEVFNWSASGSIITEGLATMFPTIVVYVMDVERCPTTFMSNMLYACSILYKTRLPFLVALNKIDLFVMDWMTDFEAFQEAQLTRTMSLTLDTFYENLCGVSAKTGVGFTQLLTKIYKPVYEK Enthi MAGSGKTTLMAYLINLDPACPPYSPDIDIRDTVNYKEVMKDYGLGPNGAIVTSLNLYSTKVDQLVTVLQNKTFIDTPGQIEVFTWSASGQVISEALSIVAPTIYLYVVDTARNPNTFMANMTYACSILYKTKLPLIIVFTKTDVKLNQWMDDYDNYLDALLQRSLCLALDDFYKNICGVSSKTGEGVDKLLECIYYQQVQK Falba MAGSGKTTLVVYTINLDPAVIPYFANIDIRDTITFKDVMTQFKLGPNGAIMTALNLFTTKFDQVMEYLEKSIIVDTPGQIEVFTWSASGTIITEFLAHSYPTSLIYTVDLMRNATTFMSNMLMSCSILYKTQLPYIIAFNKADIFAIEWMTDPDALSDALYVRSMALVLEEFYEHLVGVSALVGSGMDEFFEALYLPMLEE Fomme1 MAGSGKTTFVPYILNLDPAVTPFDTNIDIRDTVNYKEVMKQYNLGPNGGILTALNLFTTKFDQVLGLIEKRVILDTPGQIEIFTWSASGAIITDAIASSFPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDAFALEWMQDFEAFQAALLMNSMSLVLDEFYKHLVGVSSVTGDGMKEYFEAVYLPELER Fusgr1 MAGSGKTTFMPYVINLDPAVVPFESNIDIRDSVNYEEVMKQYNLGPNGGILTSLNLFATKVDQIVNLLEKRILVDTPGQIEVFVWSASGTILLESLASSFPTVIAYVIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFEAFQEALLLNSMSLMLEEFYAHLVGVSSRLGTGVDEFFEAVYQPELER Galma1 MAGAGKSTFVPYILNLDPAVVPYEPNIDIRDTVNYQEVMKQYNLGPNGGILTALNLFTTKFDQVLNLVEQRVILDTPGQIEIFTWSASGAIITDAVASSLPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALEWMSDFEEFQAALLMNSMSLVLDEFYRNLVGVSSLTGDGFKEFLEAVYLPELER Ganpr1 MAGSGKTSFIAYCINLDPAVVPFPANIDIRDTVNYKEVMKQYNLGPNGGILTSLNLFTTKFDQVLGLVEKRIILDTPGQIEIFTWSASGQIVAEALAASYPTVVAYVVDTPRQPSTFMANMLYACSILYKTRLPFLLLFSKTDVYALDWLQDYESYQRALLANSMCLVLEEFYRNLAGVSAVTGQGVDGFLEEVYRPYLAK Gloin1 MAGSGKTTFMPYVINLDPAVLPFTANIDIRDTINYKEVMKQYNLGPNGGILTSLNLFTTKFDQVLDFVSKRIIMDTPGQIEIFTWSASGAIITDALAATYPCAVAYIIDTPRSPSTFMSNMLYACSILYKTKLPFIMVFNKTDVFAVEWMTDFESFQQALLMNSMCLVLEEFYQHLVGVSAVTGAGMDEFFGAVYKPELEK Hisca1 MAGSGKTTFMPYVLNLDPAVVPFESNIDIRDSINYKEVMKQYNLGPNGGILTSLNLFATKIDQIISILEKRILIDTPGQIEVFVWSASGSILLETLASSFPTVIAYVIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDV-VAEWMSD-SKLSGALILNSMSLMLEEFYRHLVGVSAMTGDGIDEFFEAVYKTELER Klula1 MAGAGKTTFMPYVINLDPAVVPYGANIDIRDSIKYKKVMENYELGPNGAIVTSLNLFSTKIDQVLKLVENKCIIDTPGQIECFVWSASGQIITESFASTFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPLIVVFNKSDVFAKEWMTDFEAFQTALLVNSMSLMLEEFYSQLCSVSSFTGDGFDEFLNVVYKAERER Lacbi2 MAGAGKSTFVPYILNLDPAVVAYEANIDIRDTVNYQEVMKQYNLGPNGGILTCLNLFTTKFDQVLDLVEKRVILDTPGQIEIFTWSASGAIITDAVASSLPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALDWMADFEEFQAALLMNSMSLVLDEFYKNLVGVSSMTGDGIKEFFEAVYLPELEK Lenti61 MAGAGKSTFVPYVLNLDPAVTPYEANIDIRDTVDYHKVMKEYNLGPNGGILTALNLFTTKFDQVLDLVEKRVILDTPGQIEIFTWSASGAIITDAIASSLPTVVAYIIDTPRSPATFMSNMLYACSILYKTKLPFILVFNKTDVFAVEWMHDFEAFQAALLMNSMSLVLDEFYKHLVGVSSVTGAGVKEFFEAVYLPELQR Malgl1 MAGSGKSTFVPYLINIDPAVLGYAPNVDIRDTIDYNRVMEEYKLGPNGGILTSLNLFTTKFDQVLQLADKRIVLDTPGQIEIFTWSASGSIITDALATSMPTVLVYVVDTPRAPATFMSNMLYACSILYKARLPFVLVFNKTDVFALEWMHDFEAFQRAILMNSMSLVLDEFYKNIVGVSSATGDGMDAFLDAIVRPELEK Mellp23 MAGSGKTTFVPYIVNLDPAVLPFQANIDIRDTVDYKEVMKQYRLGPNGGILTALNLFTTKFDQVLNYIEKRILVDTPGQIEIFTWSASGAIITDAIASSLPTVVAYVIDTPRAPATFMSNMLYACSILYKTRLPFILVFNKTDVFALEWMQDFEKFQEALLMNSMSLVLDEFYKNLVGCSAMTGFGMKEFFEAVYRPELLK Mnele MAGSGKTCFMPYVINLDPAVLPYPANIDIRDSVKYKEVMKQYQLGPNGGIITSLNLFATKFDQVLDILEKKVLIDTPGQIEVFTWSASGTIISDAIARSYPTVIAFIMDTVRNPVTFMSNMMYACSIMYKTRLPLIVVMNKTDIFAVEWMNDFETFQEALLSRSMSLVLDEFYKDLVGISAVTGQGCANFFREVYIPHLEE Monbr MAGSGKTSFVTYLVNLDPAVVPFDPNIDIRDTVNYKEVMKQYGLGPNGGIVTSLNLFATKFDQVMALLEQRMIMDTPGQIEVFTWSASGQIITETLASTFPTVVAYVVDTARSPVTFMSNMLYACSICYKTRLPFVLVFNKSDLFALDWLKDYESFNEAILARSMGLVLEEFYTQLVAVSAFTGAGMDDFFEAVYKTMLQT Morel2 MAGSGKTTFMPYILNLDPAVLPFSANIDIRDTVNYKEVMKQYNLGPNGGILTALNLFTTKFDQVLGFVEKRILVDTPGQIEIFTWSASGSIITDTLAATYPTMIAYIIDTPRAPATFMSNMLYACSILYKTKVPFILVFNKTDVFAVEWMTDFEAFQEALLMNSMSLVLDEFYAHLVGVSAVTGAGMDDFLKAVYKPELER Mucci2 MAGSGKTTFMPYVLNLDPAVLPFTANIDIRDTVNYKEVMKQYNLGPNGGILTSLNLFTTKFDQVLNLVAKRILVDTPGQIEIFTWSASGAIITDTLAASYPTMIAYIIDTPRSPATFMSNMLYACSILYKTKLPFILVFNKTDVFAVEWMTDFEKFQEALLMSSMSLVLDEFYNHLVGVSAVTGAGVDDFFQAVYKPEIER Mydma MAGSGKTTFVPYVINLDPAVIPYPANIDIRDTVDYKEVMKQYNLGPNGAIMTSLNLFVTKFDQVLNFVENKIIIDTPGQIEVFTWSASGAIITESLASALPTIIVYVMDTARNPVTFMSNMLYACSIMYKTKLPFIVLLNKIDIFITDWMTNFDSFQDALLTRSMSLVLDEFYEHLVGVSSVTGLGMDNFMSAIYKPELEK Neucr2 MAGSGKTTFMPYVINLDPAVSPFESNIDIRDSVNYKEVMKQYNLGPNGGILTSLNLFATKVDQVLGLLEKRILVDTPGQIEVFVWSASGQILLESLASSFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKSDVFAKEWMTDYDAFQAALLLNSMSLMLEEFYAHLVGVSSLYGTGIDEFFAAVYQPELER Orpsp11 -----------------------------------------------------------------------ILLDTPGQIEIFTWSASGAIITDTLAASYPTVIAYIIDTPRSPATFMSNMLYAC---------------------------------------------------------------------------- Pench1 MAGSGKTTFMPYVVNLDPAVVPFESNIDIRDSINYKEVMKQYNLGPNGGILTSLNLFATKVDQIISLLEKRILVDTPGQIEVFVWSASGSILLETMATSFPTVIAYVIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFDAFQQALLLNSMSLMLEEFYRHLVGVSSMTGDGVEEFFEAVYKPELER Phybl2 MAGSGKTTFMPYVVNLDPAVLPFTANIDVRDTVNYKEVMKQYNLGPNGGILTSLNLFTTKFDQVLDLIAKRILVDTPGQIEIFTWSASGSIITDTLASTYPTVIAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFAVEWMTDFEKFQEALLMNSMSLVLDEFYSHLVGVSAVTGNGVEDFFAAVYKPEIER Picst3 MAGSGKTTFMPYVINLDPAVVPFGANIDIRDSVKYKKVMEEYNLGPNGAIVTSLNLFSTKIDQVIKLVEKRVIIDTPGQIECFIWSASGAIITEAFASTFPTVVAYIVDTPRSPTTFISNMLYACSILYKTKLPMIIVFNKTDVFAKEWMLDFEAFQSALLVNSMSLMLEEFYSQLVGVSSYTGEGFDEFLSAVYKAERDR Plicr1 MAGAGKSTFVPYILNLDPAVVPFEANIDIRDTVNYQEVMKQYNLGPNGGILTALNLFTTKFDQVLGLVEKRVILDTPGQIEIFTWSASGAIITDAVASSFPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALEWMQDFEAFQAALLMNSMSLVLDEFYKHLVGVSSMTGDGVKEFFDAVYLPELER Polpo MAGSGKTTLLTYIINLDPAVLPYTPNIDIRDTVNYKEVMKQYGLGPNGGIVTSLNLFSTKFDKVLEIVEKRIIMDTPGQIEVFTWSASGGIITELMASSFPTVLVYIIDTPRDPTTFMSNMLYACSIMYKSKLPMVVAFNKIDVFAQEWMNDFESFQDALLTRSMSLVLEEFYSTLVGVSAVDGTGIDEFFEKIYKADLDK Pucgr2 MAGSGKTTFVPYILNLDPAVLPFQPNIDIRDTVNYKQVMKQYNLGPNGGILTSLNLFTTKFDQVLSYVEKRVLIDTPGQIEIFTWSASGAIITDAIASSLPTVVAYIIDTPRAPATFMSNMLYACSILYKTRLPFLLVFNKTDVFALEWMEDFESFQQALLMNSMSLVLDEFYKNLVGCSAMTGFGMKEFFEAVYRPELVR Punst1 MAGAGKSTFVPYILNLDPAVVPFEPNIDIRDTVNYKEVMKQYNLGPNGGIVTALNLFTTKFDQVLDLVEKRVILDTPGQIEIFTWSASGAIITDAVAASFPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALEWMHDFEAFQEALLMNSMSLVLDEFYKHLVGVSSMTGDGIKEFFDAVYVPELER Rhior3 MAGSGKTTFMPYVLNLDPAVLPFTANIDIRDTVNYKEVMKQYNLGPNGGILTSLNLFTTKFDQVLDLVAKRILVDTPGQIEIFTWSASGAIITDTLAATYPTMVAYIIDTPRSPATFMSNMLYACSILYKTKLPFILVFNKTDVFAVEWMTDFEKFQLALLMSSMSLVLDEFYNHLVGLSAVTGAGVDDFFKAVYKPEIER Rhoto1 MAGSGKTTFMPYVLNLDPAVLPFDANIDIRDTVDYAEVMKQYNLGPNGGIMTALNLFTTKFDQVLGHIENRVLLDTPGQIEIFTWSASGSIITDALASALPTVVVYIIDTPRAPATFMSNMLYACSILYKTRLPFLLVFNKTDVFALEWMRDFEAFQEALLMNSMSLVLDEFYKHLVGVSAMTGKGMDELFDAVYKPELEK Rozal11 MAGSGKSTLMPYVVNLDPAVLPFKPNIDIRDTINYKQVMKDYTLGPNGAILTSLNLFTAKFDKVLDILEQRVIVDTPGQIEVFTWSASGTIITETLASLYPTVILYVIDTPRSPVTFMSNMLYACSILYKTKLPFILAFNKIDVFAVDWMTDFEAFQVALLVQSMSLMLEEFYKHLVGVSSMTGEGMDDLFIAVYLPEIEK Sacce1 MAGSGKTTFMPYVINLDPAVVPYGANIDIRDSIKYKKVMENYQLGPNGAIVTSLNLFSTKIDQVIRLVEQKCIIDTPGQIECFVWSASGAIITESFASSFPTVIAYIVDTPRSPTTFMSNMLYACSILYKTKLPMIVVFNKTDVFAKEWMTDFESFQAAILVNSMSLMLEEFYSQLVGVSSFTGDGFDEFMQCVYKQEREK Salro MAGSGKTSLVCYVLNLDPAVLPYEANIDIRETINYKAVMKDYGLGPNGAIVTCLNLFATKFDQVLSLMEKRFLFDTPGQIEVFTWSASGTIITETLGSSFPTVVVYAIDTPRSPVTFMSNMLYACSIMYKTRLPFIIVFNKVDVFAVEWMRDYETFRDIVMARSMGLVLEEFYHNLVGVSALTGAGMEDLFSAVFKPELDE Schco3 MAGAGKSTFVPYVLNLDPAVVPFEPNIDIRDTINYQEVMKQYNLGPNGGILTALNLFTTKFDQVLGLMEKRFILDTPGQIEIFTWSASGAIITDAVASTFPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALEWMHDFEAFQAALLMNSMSLVLDEFYKHLVGVSSMTGDGVDKFFEAVYLPSILA Schpo1 MAGSGKTTFMPYILNLDPAVLPYEANIDIRDTINYKEVMKQYNLGPNGGIMTSLNLFVTKFDQVLKILEKRILIDTPGQIEIFQWSASGSIICDTLASSWPTCIAYVVDTPRSTSTWMSSMLYACSMLYKAKLPLIIVYNKCDVFAKKWMTDFEEFQQAVLVNSMSLMLEEFYRHLVSCSSVTGEGMDDFLEAVYVPEMER Sorma MAGSGKTTFMPYVINLDPAVSPFESNIDIRDSVNYKEVMKQYNLGPNGGILTSLNLFATKVDQVLGLLEKRILVDTPGQIEVFVWSASGQILLESLASSFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKSDVFAKEWMTDYDAFQAALLLNSMSLMLEEFYAHLVGVSSLYGTGIDEFFAAVYQPELER Sphar -----------YVINLDPAVLGYAPNIDIRDTINYKEVMKQYQLGPNGGILTSLNLFATRFEKVLEIIDKRTFVDTPGQIEIFTWSASGAVITESLASTFPTVVVYVIDTPRSPITFVSNMLYACSIMYKTRLPMVIALNKADVFVEEWMTDFDALQDALLSRSMGMVLEEFYNHMASVSAVTGQGIEEFFTAVYKPELER Spipu1 MAGSGKTTFMGYVVNLDPAVLPFGANIDIRDTVNYKEVMKQYNLGPNGGILTALNLFTTKFDQVLNLIDKRVLLDTPGQIEIFTWSASGAIITDTLAATYPTVVAYIIDTPRSPATFMSNMLYACSILYKTKLPFVLVFNKTDVFAVEWMTDFEAFQAALLVSSMCLVLEEFYKGIAGVSAVTGAGMDELFTAFYRPEIER Sporo1 MAGSGKTTLLPYVVNLDPAVLPFDCNIDIRDTVDYQQVMQQYNLGPNGGIMTALNLFTTKFDQVLSHIENRVVMDTPGQIEIFTWSASGQIITDALASALPTVVVYVVDTPRAPATFMSNMLYACS---QTRLPFILAFNKTDLFALDWMRDFELFQQALLMNSMSLVLDEFYKHLVGVSAMTGEGMEDLFQAVYKPQLEK Stehi1 MAGAGKSTFVPYVLNLDPAVTNFEPNIDIRDTVDYQEVMKQYNLGPNGGILTALNLFTTKFDQVLELVEKRVILDTPGQIEIFTWSASGAIITDAVASSLPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDVFALEWMQDFEAFQAALLMNSMSLVLDEFYKHLVGVSSMTGDGVKEFFDAVYLPELTR Tapde11 MAGAGKTTFMPYVLNLDPAVLPYPANIDIRDTINYKQVMKQYSLGPNGGILTSLNLFTTKFDQVLQLLDSRVLMDTPGQIEIFTWSASGAIITDSLASSFPTVLTYLIDSPRSCSTFISSMLYAVSILYKTKLPMIIVFNKTDVTRVEWMRDFESFQAALLMNSMSLVLEEFYNHLVGVSALTGDGFDDYLACLYRPELEA Thetr MAGSGKTTLLGYMINLDPAVVPYGVNIDIRDTVNYKEVMKQYGLGPNGGILTSLNLFATRFDQVLSFLESKVFIDTPGQIEVFTWSASGSIITTTLAASFPTVLLYVVDTPRAPATFMSNMLYACSILYKSKLPFVMAFNKADIKPISWMTDFEAFQEELLVRSMSLVLEEFYNHFVGVSAVTGEGMPELFEALYKPALDK Treme1 MAGSGKTTLMPYILNLDPAVMPYTANIDIRDTVDYKEVMKQYNLGPNGGILTALNLFTTKFDQVLGFVEKRVLVDTPGQIEIFTWSASGAIITDSLASSFPTVIAYIIDTPRAPATFMSNMLYACSILYKTRLPFVLVFNKTDVFALEWMEDWQAFQRDLLMGSMSLVLEEFYSNLVGVSAMTGEGMRAFFSAIYKPELDR Trire2 PTGSGKTTFMPYVINLDPAVVPFESNIDIRDSVNYEEVMKQYNLGPNGGILTSLNLFATKVDQVVNLLEKRILVDTPGQIEAFVWSASGTILLESLASSFPTVIAYIIDTPRSTSTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFEAFQEALLLNSMSLVLEEFYSHLVAVSSRVGTGIDDFFEAVYLPELER Umbra1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 MAGSGKSTFTPYMVNLDPAVLGYEPNVDIRDTVDYARVMEQYNLGPNGGILTALNLFTTKFDQVLNILEKRIVLDTPGQIEIFTWSASGSIVTDALASSMPTVVAYIIDTPRAPATFMSNMLYACSILYKTKLPFILVFNKTDAFALEWMQDFEKFQQALLMNSMSLVLDEFYKNLVGVSSVTGDGMDDFLAAVYRPELER Walse1 MAGSGKSTVLPYVINLDPAVLNYSANIDIRDTVDYSKVMKQYNLGPNGGIITSLNLFTTKFDQVLGLIEKRILIDTPGQIEIFTWSASGAIITDAIASEVPTVIGFVVDTPRAPATFMSNMLYACSILYKTRLPVLLIFNKTDAFATEWMTDFESFQAALLMNSMSLVLEEFYSNIVGISAMTGAGMQEFFEAVYKPELER Zygro1 MAGSGKTTFMPYVINLDPAVVPYGANIDIRDSIKYKKVMENYGLGPNGAIVTSLNLFSTKIDQVIKLVENKCIVDTPGQIECFVWSASGSIITESFASTFPTVIAYIIDTPRSPTTFMSNMLYACSILYKTKLPMILVFNKTDVFAKEWMTDFEAFQRALLINSMSLMLEEFYSQLVSVSSFTGQGFDDFLNVVYKVERER [Cluster2050.fasta_al_trimmed; alignment length = 212] Allma1 ILCWNSDTAYLFAMILLWYGRDCLGRRSLLLSESVRMRAQALAP-LAVLFSGGLDCTILASPIHLLNVAFPDRRTARQALAELRTWRLLEINVPYAVALMAPLDTVMDMSIAMAFYFAARVLFSGLGADELVGGYGRHRLGEELQLEVDRIASRNLGRDDRIVSHFGKEVRFPYLDKRVVTFLLPVHWKCDKILLRLVAKRAVQFGSRTAKM Ashgo11 ILQFNNDTQYIFAYTILYFGRDNVGKRSLCLQRSTRQSLESIAKHASVLFSGGVDCSVVAAVLELLNVAFPDRKLAIESAAQLMDIRLVEVDVPYNEDLIYPKQTEMDLSIAIAFYFAARVLFSGLGADELYGGYHKFALVVELTRQINNIHDRNLNRDDKVLACHGVEARYPFLDEKVIKASLPISYKNDKMILRKLAKRAIQFGARSAKM Aspfu1 VLCWNNDTESIFSFVFLYFSRDCLGRRSLLLRQSLHLRIQKVVK-VAVLFSGGLDCTLLAESIDLLNVAFPDRITGRAAFAELRNWRFVAIDIPYTERLMRPHNTEMDLSIACALYFASRVLLSGLGADELFAGYARHGLIDEIHLDVSRLGKRNLGRDDRILSNWGREARYPFLDEDFVSYVAPVWEKCGKRALRLLAKRAIQFGSRTAKM Aurde31 ILCWNNDGAKLYAFVFLYFGRDPLGRRSLLLDSSVRLRVQDIAR-VAVLFSGGIDSSMVAEPIDLLNVAFPDRVTGLEELEELRRWNFVEVNVDYQEALMHPSKTIMDLSLALALYFASRVILSGLGSDELLGGYGRHKLLDELQLELSRIPTRNMGRDDRIISSHGKEARYPFLSLSVVNFLLPVHLKVDKMLLRAAAKRAMQFGSQSARM Batde5 YLCFNNDTTMLWAIVFVYFGRDHLGRRSLLLANAVRTRTENIAR-LGILFSGGLDCITLAEPIDLLNVGFPDRLTGRLGATELREWRFVCINVPYTENLMTPLNT----SIAMAFWFASRVLLSGLGADEQLGGYGRHKLITELQLDVSRISTRNLGRDDRIISSHGKEARFPFLDRNVVSLLLPIHLKTDKLVLRLVAKRAVQFGARTAKM Botbo1 ILCWNNDGALLYAFIYLFFGRDPLGRRSLLLERSVILRVRDISR-VAVLFSGGIDCTILAEPIDLLNVAFPDRVTGLEEVEELRTWNFVHIDVTYEEALMYPSRTIMDLSLSLALYFASRVLLSGLGSDELLGGYARHRLIDELQLDLTRLPTRNLGRDDRVISSNAKETRYPFLSLSLVAHLLPVHLKLDKALLRLAAKRAMQFGSRSARM Botci1 ILCWNNDGQVIFAFVFIYCGRDRLGRRSLLLCESLKPRILTIVR-LAILFSGGLDCTVLAQEIDLLNVAFPDRETGRKAHQELRTWRFVAVK-----------NCRLDTST----------------------------------------------------------------------------------------------------- Caeel YLVYSSVNSIVWSIIYLFIGRDVFGRQSLVVIDATKILLKNYSH-VAVCLSGGVDSTFVAMQIDLINVAFPDRKRARKALESFRQFRLILVNVDSQTDAAQPASSVLDDSLSCVLWFAVRTCLLGSGADELLAGYARHRVAEECENELRRLGSRNGGRDARVAAQLGKTILSPLLEDTVVTWLLPVDSKWDKQLLRETVKQAMQFGSRMAKM Canalb1 VLQFNNDTQFIFAIILIYFGRDSIGKRSLCLKKSIWKRQDSISK-LAVLFSGGLDCTIIATPIDLLTVGFPDRKLAIKSWFHLLNLQLIEINVDYKSKLMYPYNTEMDLSIAIAFYFASSVLFSGLGADELFAGYSRHELQESLNYDISIIHQRNLSRDDRVISCWGKELRYPYLDENFIDWVIPPQLKFKKYILRQLAKRAIQFGAKSAKL Cangl VLQFNNDTQFLFAFTIIYFGRDTIGKRSLSLSGATRKRVESISP-ISILFSGGLDCSVITATIELLNVAFPDRQLAVKSYSELINIKLIEVDVSYAEDLMYPKNTEMDLSIAIAFYFASRVLFSGLGADELYGGYYKLSLANELTTQINNIYRRNLNRDDKVIASNGVEVRYPFLAEEVVEFSIPLNYKRDKMILRNIAKRAIQFGAKSAKM Capow VFAWNNDTQIVFAFVFLFFGRDYFGRRSLLLAEAVRRRVCAV-G-IAVLFSGGVDCTVIACPVDLINVAFPDRLSARASLLELARFRLIQADIPRAESLVQPLGTVMDLSIGAALWFAARVLLVGMGADEQLAGYGRHRLVEEVALDVRRISARNLGRDDRCISDHGRESRIPFLDENVVALLLPIFTKANKILLRRVAKRAIQFGSRIARM Catan2 ALCWNNDTALVFAFAFLYFGRDVFGRRSLLLSESVRVRVLAHAP-IAILFSGGLDCSILAVPIDLINVAFPDRITARARLSELRHWRLLECNVPYARRVMKPTNTVMDLSIALALWFAARIVLSGLGADEQCGGYSRHRLARELQVDVARIATRNLGRDDRIISDHGREVRLPFLDARVVGYLLPVHFKCDKVILRVLAKRAIQFGARSAKL Cioin ILLWNSDTTALWSFVYVYFGRDYFGRRSLVLKRSVMKRTS--CN-IGVLFSGGVDCSVLAEAIDLLNVAFPDRITGRSSYQELRKWNFVEINVTLEEMLSCPKSTVLDDSIACAIWFASRVLLCGMGADEQLAGYSRHRVGDEINMEVERISARNLGRDDRIISDHGKEARFPYFDEEVVQFLLPVHVKADKILLRGAAKRAIQFGSRIAKA CocheC53 VLCWNNDSQLVYAFVFVYYGRDCLGRRSLLLLESLQVRTEHVAR-VAVLFSGGLDCTILAAPIDLLNVAFPDRITGRSSHAELRTWRFVAINVPYSETLMYPHNTEMDLSISFALYFASRVLLSGLGADELFGGYQRHDLIEELELDFSRLGKRNLGRDDRVISDSSKEVRFPYLDEDFIALALPVTAKCDKRALRLLAKRAIQFGARTAKM Coere1 IFCWNNDGAVLYAFVYLWFARDYLGRRSLLLTNAIKVRVESISR-VGVLFSGGVDCITIAEPIELFNVAFPDRKTGRQGWEELREWRFVEVDVPYSQQLLIPSDTVMDMSIGMAIWFASRVLLLGMGADEQLGGYSRHRLGQEIELDVSRIATRNLGRDDRIISDNAKEARFPFLAANVVRFLIPLGRKMDKLLLRLLAKRAIQFGARTAKM Conco1 WMAFNNDTKIIYSILYLYFGRDPMGRRSMLLSQSVKSRVENIKR-VGILFSGGLDCAILALAIDLLNVGFPDRLTGRQTYEELRKWNFVEINVPYEQRLIFPSDTVMDLSIALAFWFASRVLLSGLGADEQFGGYSRHLLLSEIQLDVDRLPSRNLGRDDRVISDHSKEVRFPFLDREFINLVIPIQYKMDKLMLRQVAKRAVQFGARTAKM Conpu1 ILCWNNDGVRLYAFVYLYFGRDPLGRRSLLLDMSVMLHVCSISR-VAVLFSGGIDSTVVAEPIDLLNVAFPDRVTGLQEVEELRVWNFVEIDVPYAEQLMWPRETVMDLSLAMALYFAARVLLNGLGSDELMGGYGRHQVIDELQLELDRIPTRNLGRDDRVISSHGKETRHPFLSLSVVNYLLPVHRKLDKTLLRLAVKRAMQFGSHSARM Copci MLCWNNDGVNIKLNKLLYFARDPLGRRSLLLDRSVALRVKDIAR-LAILFSGGIDSTILTEPIDLLNVAFPDRKTGLQELEELRKWNFLEINIPYEENLMLPSRTVMDLSLALALYFASRVVLSGLGSDELLGGYGRHRVIDELQLEIDRIPQRNLGRDDRIISSHGKETRHPFLSLDVVSFLLPVHYKLDKTLLRLLAKRAMQFGSHSARM Croqu1 VFLWNNDGERLYAFIYLWFGRDPLGRRSLMLGDAVRRRVMDIPS-VAILFSGGLDCTTLAQSIDLINVAFPDRKTGESSWAELRIWRFVKVDVSISEQLMKPNFTVMDLSIAAALYFASRVVLSGLGADELLGGYSRHRLIDELQLDLDRISTRNLGRDDRIIAQHAREVRYPFLDSTVVRTLMAVHLKCDKLVLRCLAKRAIQFGARSAKL CryneH991 VLGWNNDTRKIFACIYLYYQLDPLSRRSLLLQASVRRRVENIAK-VAVLFSGGIDCTFLADPIDLINVSFPDRLSGLEAVEELREWRFVEVNVPYEEELMYPSVTEMDLSLAYPLYFASLVYISGLGADEQLGGYSRHRLIDETQMDLTRLPTRNLSRDDRLISSHARDARYPYLSLSFIAHLLPIWLKCDKRLLRLAVKRAMQFGTRSAKV Crypa2 VLCWNNDGEAIFAFVFLYFGRDRLGRRSLLLTESLRLRVLNVTK-VAVLFSGGLDSTMIAQGIDLINVAFPDRGTGRKSFAEVRAWRLIAVSFPL--SLIYPHNTEMDLSIACALYFAARVLLSGLGADELFGGYSRHALVDELRLDVSRLGKRNLGRDDRAMSHWGREIRFPFLDEDLVRWAVPAWQKCDKRVLRLLAKRAIQFGSRTAKM Debha1 ILQFNNDTEFIFAFTILYFGRDYIGRRSLLLNDACYIRQSTIAN-IGILFSGGLDCTILA--IDLITVGFPDRQLSKKSWFHLFSIRLIEINVDYKEKLMYPCNTEMDLSIAIAFYFASKVLFSGLGADELFAGYSRHELSDSLIYDIKIIHERNLGRDDRVISSWGKELRYPYLDEKFINYVVEPNLKLYKWILRELAKRAIQFGAKSAKM Dekbr2 ILQFNNDVQFAFAYSIIYFGKDVLGRKSLLLEESIRKRIFTVAN-YAILFSGGIDCTLLAPKIDLLNVSFPDRKLAVKSWKHLVQFNSIEINITYETSLMYPKDTVMDLSIAAAFYFASSVLLSGLGADELFGGYTRHELRDELQHDLSNLYIRNMARDDRVISCWSKEVRYPYLDMQFVRFSVPLDLKLHKYALRSLAKRAVQFGARSAKM Dicdi TLLWNNDTCLLFAFLYLWFGRDVLGRRSLLISDSINVRLNNLSR-LGILFSGGLDSMVLAEPIHLINVAFPDRKAAISGLKELRQWKLIKVNVGTKEQLSYPAITIMDMTICLALWFAGR------------------------------------------------YPRFPYLDESLISYLIELPYICDKRILREVG--PIQFGSRSSKQ Dmel IFLFNSDTTWIHCLIILYFSRDALGRNSLLLSDSIKNRVRNMAK-LCILFSGGLDCTILAEPIELINVAFPDRKTSLVSVNELRCWNLLKVNVTRLEHLIYPLDTVLDESLGCAFWFASHVALIGSGADELFGGYTRYRVQNELERDWQRISARNLARDDRIIADTGKTARSPFIEENFVKFILEVYQKCCKLLLRLYGKRAIQFGSRIANK Enthi KICYSNKYNFIYAISFIQFCSDRFSSYSLLLSKAVKDCIDNT---IPILFSGGIDSSLIAREVELYNVSCPDRLCAKAVLENLKVIHFIEIDIQKEIPIIYPNDTVMDLSIATATSLALTRVLCGQGSDEQLGGYGRHRLSKELEMDFCRLWSRNTSRDSRVNDYCNATCFYPFLNSDVIRFIIPEDFLVKKWILREVSKTAIQFGTRMAKL Falba -----HDEELL-----GAHPPSCHTRRGVC------------AE--------GVDTGSFI--ICHLNSELPS-----GEFSQLRDWRLVCVNAPRAEAVCLPGRTVLDLSLARVLWFGARTLLVGTGADELFGGYTRHRLEAELRADLIRLPGRNFGRDDRAVGAWGRHLSAPFACERLMREVWPVACRAPDTLMRENAKRAMQFGSRVADP Fomme1 VFCWNNDGIKLYAFSYIFFGRDPLGRRSLLLSRSVRFMVQHIAR-VAVLFSGGIDSTILAEPIDLLNVAFPDRITGLEELAELRQWNFVEVDVTFEENLMYPCRTVMDLSLALALYFASRVLINGLGSDELLGGYGRHRVIEELQLEIDRIPKRNLGRDDRIISSHGKEARHPFLSLSVVNFLLPVHHKVDKMLLRLASKRAMQFGSHSARM Fusgr1 VLCWNNDGEAIFAFIYLYYGRDRLGRRSLLLAESLRLRVLDVAR-VAVLFSGGLDCTVLARCIDLINVAFPDRMTGRNAFAELRTWRFVTVNVPYAERLIYPHNTEMDLSIGCALYFAARVLLSGLGADELFGGYGRHGVVKELKLDVSRLGKRNLGRDDRAMSHWGREVRFPYLDERFVKWATPVWEKCDKRVLRLVAKRAIQFGARTAKM Galma1 ILCWNNDGSKIYAFVLLYYGRDPLGRRSLLLDRSVLLRVRDIAR-VGVLFSGGIDCAVITEPIDLLNVAFPDRVTGIMEVEELRIWNFVEVNVPYEDSLMFPGRTVMDLSLALALYFASRVLLNGLGSDELLGGYSRHRAIAELQQEIDRIPTRNLGRDDRVISAHGKETRHPFLSLSLVSFLLPVHFKMDKMLLRLAAKRAMQFGSHSARM Ganpr1 LFFWNSDTRILWAFALLFIGRDILGRRSLLINNSVRLRVECITR-LAILFSGGLDCSVLAEGIDLINVAFPDRITALASLAELRPWRLVAVNIPFSASLITPLSSVMDRDLGGVFWWAARVFLSGLGADELLGGYSRHRLAESLAADAARLPSRNLGRDDRVVSDWGREVRYPFLDPGVLDWCTPIWEKVAKWVLRMAAKRATQFGSRVAKL Gloin1 VLLWNNDTKYLYAIIYLWFGRDCLGRRSLLLGDSVRRRIIDIAR-VAIMFSGGLDCICLAEAIDLLNVGFPDRLTGRQGVEELRKWNFVEVNVPFEEELMAPSDTIMDLSIAMAFWFAVRVILVGVGADELLGGYSRHRLIEEIQLDVDRISTRNLGRDDRIISSHSKESRFPYLASNVVSFLLPMYIKADKLLLRHVAKRAIQFGAKTAKM Hisca1 VLCWNNDAKCVFSFVFVFYGRDRLGRRALLLRESLKLRLANISK-VAVLFSGGLDCTILAEPIDLLNVAFPDRITGRLSHTELRPWRFVAINIPYTERLMRPHNTEMDLSIACALYFASRVLLSGLGADEIFAGYTRHALVDEIALDVGRLGKRNLGRDDRVICHWGREARYPYLDEDFLAWACPIWEKCGKRSLRLLAKRAIQFGSRTAKM Klula1 LLQYNSDTEYIFAYAIVYFGRDSIGKRSLSLRRSVYQRIVTIGN-ISILFSGGLDCSVITTIIELLNVGFPDRILAIKSAQLLVNIKLIEVDVPYTDDLMYPKNTEMDLSIAIAFYFASRVMFSGLGADELYGGYHKFSLVIELQKQIAQIHDRNLNRDDKVISNHGIEVRYPFLDERVVQFSLPLNYKVNKHILRVMAKRAIQFGARSAKM Lacbi2 ILCWNNDGVKVYAFVFLFFARDPLGRRSLLLDRSVLLRVRNIAS-VAILFSGGIDSTVLAEPIDLLNVAFPDRVTGLDELEELRVWKFVEINVPYQESLMIPGRTVMDLSLALALYFASRVVISGLGSDELLGGYGRHRVIKELQLEMDRIPTRNLGRDDRIISSHGKETRHPFLSLDVVRFLLPIHLKMDKMLLRLLAKRAMQFGSHSARM Lenti61 LLCWNNDGVKLYAFLYLYFGRDPLGRRSLLLDRSVMLRVRDIAR-VAVFFSGGIDSTMVAEPIDLLNVAFPDRLTGLQEVEELRTWNFLEINVPYEEALMYPSRTVMDLSLAIALYFAARVLLNGLGSDELLGGYGRHRVIDELQTEIDRIPTRNLGRDDRVISSWGKETRHPFLSLSLVNFLLPVHLKMDKLLLRLAAKRAMQFGSHSARM Malgl1 WLVWNNDARVLYAFVL--------------LSESVRCRVQGISR-VAILFSGGLDCTVLAEPMDLLNVSFPDRVTARDSCAQLCQFRLVEVNVPYAEALMYPQATVMDLSIAAALFFASRVLLSGLGADELLAGYARHRLTQELQMDLDRIPTRNLGRDDRIFSSHNREARYPYLARSVTTFLLPAQAK--KHLLRCLAKRAIQFGARSAKM Mellp23 IFLWNNDGEILYAFVYLWYGRDPLGRRSLMLGDAVRRRVASIAS-VSVLFSGGLDCTTLAESIDLINVAFPDRKTGESSWIELRLWRFVKVDVTISEQLMKPNFTVMDLSIAAALYFAARVFLSGLGADELLGGYSRHRLIDELQLDLDRISTRNLGRDDRIIGHHGREVRYPFLDSTVVHTLIPVHLKCDKLLLRYLAKRAIQFGARSAKI Mnele HLIYNSDTEYLTAVIILWFWRDYFGRRSLLLSESVRVRDMCCAR-VAVLFSGGIDCTVLAEPIDLLNVSFPDRLSAVASLGDLRTWNLIKVNVSVEEDLVYPHNTVLDDSIGCALWFAARLLFSGIGADELLGGYSRHRVLQQLQLDIGRISERNLGRDNRVIGDHKRDCVAPYLDERFVSFVLPIQYKVDKVILRKVAKKAIQFGSKIAKL Monbr ------------------------------------------------------------------------------------------------------------------------VLLLGMGADEQFGGYSRHRALCQVEQDIRRIPTRNLGRDDRVIADHGREGRYPFLDEAFMSLALPLAVKADKKLLRMMAKRAIQFGSRIAKM Morel2 VLLWNNDGRVLYAFVYVYFGRDCLGRRSLLLGDSVRRRVQDIAR-VGILFSGGLDCLCLAEAIDLLNVGFPDRTTGYESLAELRHWNFVEVNVPFEEERIAPLETVMDLSIAMAFWFASRVLLSGLGADEQLGGYSRHKLIHELQLDLDRISTRNLGRDDRIISDHGKEARYPFLSTNVVQFLLRVDLKVDKILLRHVAKRAVQFGARTAKM Mucci2 TLCWNNDTQVLFAFVYVYFGRDCLGRRSLLLGESVKKRVADIAR-VAILFSGGLDCICLAESIDLLNVAFPDRLTGKAGVEELRTWNFVEINVPYPEDRMFPLDTVMDLSIAMAFWFASRVLISGLGADEQLGGYSRHRLIQETQLDVDRISTRNLGRDDRIMSDHGKEVRFPFLSTYVVDWLQPIQLKMDKILLRHVAKRAIQFGAKTAKM Mydma VLLWNNDTEVLRAYIYLWYGRDCFGRRSLLLLKSVRTRVNNLPC-VGILFSGGIDSVVLAEPIDLINVAFPDRISGRLALKELRVWNFIEVDVTLDEDLVYPLDSVLDDSIGCALWFAARVLLCGMGADEQLGGYSRHRLAAEMHMELDRISSRNLGRDDRCISDHGREVRFPFLDENVVSYLLPTCVKCDKILLRELAKRAIQFGSKIAKI Neucr2 VLCWNNDGEEIFAFVYVFFGRDRLGRRSLMLINSLSLRVLNITR-VAVLFSGGLDCTVLAQGIDLLNVAFPDRITGRKSFAELRAFRFVAVNVPYTKSLIYPHNTEMDLSIGYALYFAARVLLSGLGADELFGGYSRHPLVDELLLDVGRLGKRNLGRDDRAMSHWSKEVRFPYLDERLVKWATPAWEKCDKRVLRLLAKRAIQFGARTAKM Orpsp11 VLCWNSDTLILWAFIYLWFGRDYLGRRSLLLGEAVRKRMTNISK-VGLLFSGGLDCMCLAEPIDLLNVSFPDRITGRRGVEELRKWNFVEINIEYSEDLICPLTTLMDFSIAMSFWFASRILLSGLGADEQLCGYGRHRLIEETQLDISRISTRNLGRDDRIISDHGREVRFPYLDEQVMNYLLPIHLKADKLLLRHLAKRAVQFGARAAKM Pench1 VLCWNNDTERVFAFVFLFYSRDCLGRRSLLLRQSLELRIQNIAK-TAVLFSGGLDCTLLAEPIDLLNVAFPDRITGRAAHIELRTWRFIAIDIPYTERLMRPHNTEMDMSIACALYFASRVLLSGLGADELFAGYGRHSLIAEIDLDVSRLGSRNLGRDDRVLSHWGRETRFPFLDEDFVAWVAPVWEKCGKLALRLVAKRAIQFGARTAKM Phybl2 VLSWNNDTEVLFAFVFLWFGRDCLGRRSLLLSESVRRRVADVAR-VAILFSGGLDCITLAEPIDLLNVAF-------------RIWNFVEINVPYPEELMYPLDTVMDLSIAMAFWFASRVLLSGLGADEQLGGYSRHKVIEETQMDVDRISTRNLGRDDRIMSDHGKEVRFPFLSTDVVNWLCPIYIKMDKLLLRNVAKRAIQFGAKTAKM Picst3 ILQFNNDTLFIFAIVLVYFGRDCVGRRALSLKNSTLVRQEAIAT-LAILFSGGLDCSVIAYNVDLLTVGFPDRELSKKSWFHILNIRLVEINVSYKDNLMYPCNTEMDMSIAIAFYFASAVLFSGLGADELFAGYSRHELSSELVHDIDIIHRRNLGRDDRVISSWGKELRYPYLDEKFISMVIEPNFKFTKYILRQLAKRAIQFGAKSAKL Plicr1 VLCFNNDGVKLYAFVYLYFGRDPLGRRSLLLDRSVMLRVQNISR-VAVLFSGGIDSTIITEPIDLLNVAFPDRVTGLKEVEELRIWNFVEVNVPYKEALMFPSRTVMDLSLAMALYFASRVLLNGLGSDELLGGYGRHRVIEELQLEIDRIPTRNLGRDDRVIASHGKETRHPFLSLSVVSFLLPVHYKMDKMLLRLAAKKAMQFGSHSARM Polpo ILMWNNDTEFLFAFVYLWFGRDVLGRRSLLLSRSIATRVTGLGR-VGVLFSGGLDSMVLAEPIHLINVAFPDRKTAISGLYELREWILIKVNVTDQWQLSYPAITIMDMTISLALWFAGRVLLMGSGADEQLAGYGRHRLQSELNKDFNRIWKRNLGRDDRVISSNRREPRFPYLDENVIEYLVPLSYVCDKRILRELAKKAIQFGSRSSKQ Pucgr2 LLLWNNDGQAVYAFIYIWFGRDPLGRRSLMLNNSLRRRLHNISK-VAILFSGGLDCTTLAESIDLINVAFPDRHTGEESWKELRTWRFVKVDVWMKDELMWPNDTVMDLSIAAALFFAAWVFLSGLGADELLGGYSRHRLIQELQLDIDRIPTRNLGRDDRIIAHHGREVRYPFLDRDVIDTLLPVHLKCDKLLLRVLAKRAIQFGARSAKL Punst1 -----------------------------------MLQVRDIAR-VAVLFSGGIDSTVLAEPVDLLNVAFPDRVTGLTEVEELRTWNFVEINVPFEEALMWPSRTVMDLSLANALYFASRVLLNGFGSDELMGGYGRHRLIAELQLEIDRIPTRNVGRDDRVISAHGKETRHPFLSLSLVSYLLPVHLKTDKMLLRLAAKKAMQFGTHSARM Rhior3 ILCWNNDTQALYAFVFLWFGRDCLGRRSLLLSQSVKSRVADIAR-VAILFSGGIDCTFLAEPIDLLNVAFPDRVTGRASLEELRSWNFVEINVPYVEDLMFPLDTVMDLSIAMAFWFASRVLISGLGADEQLGGYSRHRLIQEM-------------------------------------------------------------------- Rhoto1 VLLWNNDGQKLYAFVYLYFGRDPLGRRSLLLETAVRARVSTVAR-IAVLFSGGLDCTVVAEAVDLINVAFPDRLTARNAWEELRRWNLVEVDVPYQEDLMRPQNTVMDLSISIAFYFAARVLLTGLGADELLAGYARHRLIAELQLDLDRLPTRNLGRDDRIISIHGKEARYPFLAGHVVAFLQPVWFKADKMLLRLLAKRAIHFGAQTAKM Rozal11 VFLWNGDTKAVYAFILLYFGRDFLGRRSLLLTESMKKRILNIAS-VAILFSGGLDCSVIAVTIELLNVAFPDRQSGIESYLTLRNFVFVNVNVPFEDSLMKPCSTVMDMSISLPFWFASRVLFSGLGADELLGGYGRHRLVDEMQRDLSRLNDRNLGRDDRIISDHGREVRYPFLDENLIDYWLPVRLKCDKILLRKIAKRAIQFGSKTAKM Sacce1 FLQFNNDSLYIYAYTILYFGRDPIGRRSLSLRDSVKKRVESISP-IAVLFSGGIDCSVIVPVIELLNVSFPDRKLSINSAKTLVDIKLVEVDVPYDENLMYPKQTEMDLSIAIAFFFASRVLFSGLGADELYGGYHKFALVEELTRQINNIYDRNLNRDDKVIAHNGVEVRYPFLDEYVIKLSIPINFKVNKLILRKVAKRAIQFGAKSAKM Salro VLLFNNDTQALWAIVLLWFGRDYFGRRSLVLRHAVDLRSRAFQS-IGILFSGGIDCMMIATAIDLINVAFPDRVTGISSYEEL--IRFIKVNVTQSESLVSPLETVLDDSIGCAIWFAARVLLLGMGADEQLGGYGRHRALQEVFQDVRRISSRNLGRDDRVVCDHGKEGRYPFLDESVVSFLLPLACKMDKRLLRLAAKRAIQFGSRIAKM Schco3 ILCWNNDGVRLYAFVYIIYGRDPLGRRSLLLEDSVRRRVYDIAR-VGVLFSGGIDCTVLAEPIDLLNVAFPDRVTGLEEVEELRIWNFVEVNVPFEEAIMYPCRTVMDLSLAQALYFAARVLLNGLGSDELLGGYGRHRLIRELQLELDRLPTRNLGRDDRIISAHGKEARHPFLSLDVVRFLLPVHAKTDKLLLRIVAKRAMQFGSHSARM Schpo1 VLCWNNDGAKLFAFVYLWWGRDRLGRRSLLLIKALQDRVLTISR-VCVLYSGGVDCGVLAESIDLINVAFPDRQTGLQGWQELRKWNFVAINVPYTETLIYPNDSVMDLSIGLAFYFASQVLISGLGADEQLGGYMRHLLEEELQLDIDRIPHRNLGRDDRVMSNQGKEVRYPFLDERLMALFMKTTDKMRKLILRELGKRAIQFGSKAAKM Sorma VLCWNNDGEEIFAFVYVIFGRDRLGRRSLMLIDSLSLRVLNITR-VAVLFSGGLDCTVLAQGIDLLNVAFPDRITGRKSFAELRAFRFVAVNVPYTESLIYPHNTEMDLSIGYALYFAAR---------CLFGGYSRHPLVDELLLDVGRLGKRNLGRDDRAMSHWSKEVRFPFLDERLVRWATPAWEKCDKRVLRLLAKRAIQFGARTAKM Sphar LFLWNNDTQFLFSFVYLWIGRDCFGRRSLIMSEAVRRRVVSVPN-IMILFSGGVDSMLMARFIDLVNVAFPDRLTGRQGYQELRNWQFVEVDVPIETGLLHPLQTVIDTSIGSAMWHATKVVLVGVGADEQLGGYSRHRMLLEMRMDVDRIWTRNLGRDDRIISDHGREARFPFLDEQLVSYLLPIWIKTDKILLRMALKRAIQFGTRVARN Spipu1 VLCFNNDTEAFWAMVYLYFGRDVLGRRSLLLAEAVRLRVENIAR-LAILFSGGLDCICLAEPCDLLNLAFPDRRTGRSGVAELRPWRFVEIDVPYAEELMKPLDTVMDLSIAIAFWFGARVLFSGLGADEQLAGYSRHRLVDEVQLDVERIANRNLGRDDRIISDHGKEVRFPYLAEEVLACLMPIHLKADKLLLRQLSKRAVQFGARSAKM Sporo1 VLLWNNDGEKLHALIYIYYTRDCLGRRSLLLLESIRQRVLTIPR-IAILFSGGLDCTSLAEGIDLINTSVPDRLTGLDSWRELRRWNFVQVDVPYREDLMYPQDTVMDLSIAIAFYFAARVLLSGLGADELLGGYSRHRLIEELQMDLDRLSKRNLGRDDRIVSSQSKEVRYPFLSNEVVDFLLSVWDKCDKLLLRMLVKRAIHFGARTAKM Stehi1 VLCWNNDGAKLYAFTYLFFARDPLGRRSLLLEESVRLRVCSVAS-IAVLFSGGIDSTMLAEPIDLLNVAFPDRVTGLQEVEELRTWNFVEVDVPYMEALMWPSKTVMDLSLAMALYFAARVLLNGLGSDELLGGYGRHRVIDELQLEIDRIPTRNLGRDDRTISTHGKETRHPFLSLNLVRFLLPVHYKVDKLLLRLAAKRAMQFGSHSARM Tapde11 VLCWNNDTAALYAFVYVWYGRDILGRRSLLLTDSLRIKTETLSR-IAVMYSGGVDCAVIAEPIDLLNVSFPDRVTGLQGYDELREWRFVAIDVPYREELMHPNDSIMDFSIALAFYFCARVFFSGLGADEQLGGYSRHLLIKELQCDLDRIPSRNLGRDDRILAHFGREVRWPFLDENVISFLLRLDTKMTKVILRDLAKRAIQFGSRSARM Thetr VMAFNCDSAALWALVVLLWARDRFGRRSLLLTEAVARRVVNVAS-VGILFSGGLDSMVVATAIELINVAFPDRMTGTASAAHLRTWIWVPVNVRAADETVAPAATAMDLSIGAALYFASSVLLTGLGADELLGGYTRHRLSAELALDFARLWRRNLGRDDRVVAAHGCELRLPFLDEDVVAFLLPLAWRTDKHLLRALAKRAIQFGSRIAKV Treme1 VLGWNNDTRKIYAFIYLYFAVDPLSRRSLLLTESIRKRTENIAR-IAVLFSGGVDCTLLCEPVELVNVAFPDRLSGIEALQELREWRFVEVNVTYDEDLMYPSKKEMDLSLAYPLFFASRVYFSGLGADEQLGGYSRHRLIEEIQNDVWRLPSRNLARDDRLISSFARDARYPYLDLKFLSYLLPIWLKCQKMLLRLAAKRAMQFGSRSSKM Trire2 VLCWNNDGEAVFAFIFLYYGRDRLGRRSLLLTASLQLRVLNVAR-VAVLFSGGLDCTVLAQAIDLINVAFPDRMTGRKSFAELRRWRFVTVNVPYDEDLIYPHNTEMDLSIACALYFAARVLLSGLGADELFGGYVRHALIDELKLDVGRLGKRNLGRDDRVMAHWSREVRFPYLDESLVKWALPAWEKCDKRVLRLLAKRAIQFGARTAKM Umbra1 VLCWNNDTQMLYSIVFLWFARDCLGRRSLLLGDSVRRRVIDVTK-VAILFSGGLDCLCLAQNIDLLNVAFPDRKTGRASVQELRTWNFVEIDVPYEEDRIVPLDTVMDLSIAMAFWFAARVLLSGLGADEQLGGYSRHRMIKELQVDIDRISSRNMGRDDRIISDHGKEVRFPFLSTDVVRWMTRCDLKMDKLLLRHLCKRAIQFGAKTAKM Ustma22 LLAWNNDAIVLYAFVLLYFGRDPLGRRSLLLSESVRRRVTNIAH-VAILFSGGLDCTTLAQPIDLLNVGFPDRLTGLSSYAELRRWNLVCINVAYSEELMAPSCSVMDLSIASALYFASCVLISGLGADELLGGYSRHRLTAELQLDLDRLPSRNLGRDDRILSAHSKEARYPFLDRRVLDFLTPVHRKVQKRLLRDLAKRAMQFGTRSAKI Walse1 ILCYNNDGVLLCAFVYTFFGRDTLGRRSLLLTQVVDRRVRSICK-VAVLFSGGIDCTMVAEPIELINVAFPDRQTAMEAVEELREFRLQ--------ELMYPKNTVMDLSLAAPLYFASRVLLSGLGADEALGGYGRHRLADELEMDLDRLPSRNLGRDDRVLSHHSREVRFPFLAQPLLRWLIPLHLKADKRLLRTLAKRAMQFGSRSSRM Zygro1 ILQFNNDTSFVFAYTILYFGRDDIGKRSLSLKSAIVKRVESISP-IAVLFSGGLDCSVIARTVELLNVSFPDRKLAVKSANALVDIKLVEIDVPYETDLMYPKNTEMDLSISIAFYFASKVLFSGLGADELYGGYYKFALVEELTRQINNIYNRNLNRDDKVIAANGVEVRYPFLDRHVIEFSIPINWKINKLILRKLAKRAIQFGSKSAKM [Cluster2051.fasta_al_trimmed; alignment length = 149] Allma1 MNRFFGKPTIGDAIDSVEVKIKKLDAELARYKDQMSKMRDGPSKNAIKQRAMRVLKQRKLYEGQRDQLMQQSFNMEQAQFATENLKNTLVTIDAMKVANQELKKQTKMNIDKIEKMQDEMEDLLDLANDFQDVLSRSLPDEIDEADLEA Ashgo11 MNRLFGDQLLQESSSQLDTQIAQLNFQLQGLQKKIAGMGSAVAQRPLRQRALKLLNKRKQLETSRDQLDSQLWSMSQAQMTTENLKNTAVTVNALAQTNKALRQQYQINVERLQTMQDEMADLMEQGEELQQVLAMGI-DDISESELDA Aspfu1 MNRLFGKPTLDDAIASIDVKLASLNAELSTYQAKIAKMRDGPGKNALRQKALKVLQRRKQYEAQRDQLSQQSWNMEQAGMMQDNLKNVMTTVDAMKTTTKELKKQYKVDIDKIERMQDEMADLMDIGNEIQESISRAIPEDVDEAELDA Aurde31 MNRIFGKASLNDAIGAIEVKIKKLDAELGKYKEQLSKLRNGPGKNAVEQRALRVLKQKKMYEAQLSQLTQQTFNMESAAIATENLRNTMATLDAMKVANKELQRQYKIDIDKIETMHMDMEDLLEQANEVQESLGRSVPDEIDEADLQA Batde5 MNRIFGKPTITDAIDSAEVKMRKLDAELMKYKEQMKGMRDGPGKNAVKQKAMRVLKQRKLYEGQRDQIMQQTFNMEQASMATENLKSTMVTLDAMQSANKELKKQYQVNLSKIEVVYYEMEDLLEQANEIQETIGRSLPDDVDEADLEA Botbo1 MNRIFGKASLNDAISAIEVKVRKLDAELGRYKEQMSKMRNGPAKEAVQRRALAALKQKKLYEAQIASLTQQTFNMESAALATENLRNTMATVDAMKVANKEIRKQYKIDVNQIEDMHYDMEELLEQANEIQETLGRSVPDEIDEADLEA Botci1 MNRLFGKPTLSSAISSLDVKLASINAELTSYQTKLSKMRDGPGKTAIKQKALKVLQRRKMYEGQRDQLQQQSYNMESAAMMQDNLQNVMTTVSTLKSTNAALKKQYKIDIDKIERMQDEMADLMEVGNEIQESISRSLPEEVDEAELDA Caeel MNRIFGPPDLNNAIDSIDKKIQKLDQDLMKLRDQMSKMREGPSKNLIKQKALRVLKQKRMYENQKGQLDQQAFNMDQSNFAIQGMKDNQVTVAAMKDGLKTMQKEYKMNIDQIEDLQDQMEDMLDMNNEIQEAMSRQT-PDIDEADLEA Canalb1 MNRLFGKPSLNDAIGSLDVKLSKINSELSTYQQKISRMRDGPGKSALKQKAIKLLRQRKQIEAQKDQLENQSWNMTQASMTTDNLQNTMVTINAMKTANKSLKQTYKINIDELEDLQDEMLDLIDKSNELQEALSTSVPDDISESELDA Cangl MNRIFGDQMLQESGSQLDTQIAQINFQLQALQKKMKGMKSSVGQRPLRAQALKLLNKRKQLEQMRDSIDAQSWSMTQAQMTSDNLKNTMVTVNALKSTNKALKAQYKIDIDKLQDMQDEMMDLIDQGEELQQVLATNI-EDIDEGELDA Capow MKRMFGPPTLTDAIESIEKKIEKLDVELKKYKDQLAKTRDGHGKQLLKQRAMRVLKQKRMYEAQRDQLMQQSFNMEQANFATQTMKDTITTVNAMKVGVKEMKTQYKINIDKIEDIQDEMEDLLDQANEVQESLSRSLGEDVDEADLEA Catan2 MNRFFGTPSLNDAIDSVEVKIRKLDAELARYKDQMAKMRDGPSKNAIKQRAMRVLKQRKLYEGQRDTLMQQSFNMEQAAMATENLKNTAATVDAMRVANAEIKKQYGINIEKIEKIQDEMDDLLYAANELQDVLGRSLPDDIDEADLEA Cioin MNRIFGAPTLNDCIESVEKKISKLDAELLKYRNQMKKMRPGPAKKAVQNRALRVLKQKKMYETQRDNMMSQSFNMEQTNYSIQTIKDTKNVVGAMKVGLKEMKKEHKINLDEIEDLQDDMADMLEMSEEIQETLGRST-PELDEDDLEA CocheC53 MNRLFGKPTLSSAIESIDVKLAKLNAELSTYQQKLAKMRDGPGKTAIKQKALKVLQQRKQYEAQRDQLQAQSWNMEQAGMMQDNLKNNMTTIDAMKTTTKELRKQYKINIDQIDKLQDEMADLMDMGNDIQDAISRSVPEDVDESELDA Coere1 MNRIFGPPTLNAAVTTLDEKIKKLEGEITQYKDQMRRLPEGPSKNRIKAKAVNAIKQRNMYENAREQHTQQSFNMDMVMSMQDSMKNASVTVQAMKQSNAAMKKQFELDVDKVDDIMFEASELMDQGNEVQEIMSQNMPFDVDESELDA Conco1 MNRLFGKATLSTAIDSVEVKIRKLDAELIKYREQMSKMREGPAKNAVKQKALRVLKNKKQYEGQRDNIQQQVFNMEQTNFATENLKNTQVTVEAMREANKEMKKSFNVNIDKIESMQDELEDLLEEANLVQETLGRSLSEDIDEADLDA Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------- Copci MNRLFGGPSLQDAIGSIEVKIRKLDAELARYKEQMSKLRNGPGKSAIQQRALRTLKQKKMYEAQIAQLTQQSFNMESAALTTENLRNTMATVSAMEQANKQIRKQYKIDIDKIENMHYDMEELMEQANEIQETLARSLPDEIDEADLEA Croqu1 MNRIFGKPTLNDAIDSIELKIRKLDAELIRYKDSINKLKNGPGKTAIQQRAIRVLKQKKLYESQLSQLQQQTFNMEQAIMTTDNLRNTMATVDAMKLANKEMTKQYKIKIDQIEAISYDMEDLIEQANEVQESLGRSVPDEIDQDELEA CryneH991 MNRIFGKPSLTDAIASLEVKLKKLDAELSVFKTQMSKMREGPGKAAVQQRALRVLKQKKMYENQLGQLQQQTYNMEQAAMTTENLKNTMATVDAMRVANKEMKKQYGINIDKIESIHYDMEDLIEQANDIQESLGRSVPDEVDEADLQA Crypa2 MNRLFGRPTLNSAISSIDVKLASLNAELQTYQTKLSRMREGPGKTALKQKALKVLQRRKAYEAQRDQLQSQVWNMEQAGMMQDNLKNVMTTVDAMKTTQKELKRQYKVDIDRIERLNDEMADLMDVGNEIQESLARSVPEDVDEAELDA Debha1 MNRLFGKPSLNDAVGSFDVKLSKINAELSTYQQKIARMRDGPGKSALKQKALKLLRQRKQVEAQKDQLENQSWNMTQAAMTTDNLQNTMITVDAMKAANKQLKKTYKIDVDKIEALQDEMLDLIDKSNELQESLLTSVPDEISESELDA Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi MKRFFGAPTLDEATGQMDEKINGLNQELLAYDKQIKATRPGPAQNAIKQKAIRVLQQKKMYERQRDQMASTSFNMEQTKFATESMRDTITTVSAMKQGAKDMKTQLHIKIEDVDDMQDEMQDLLDYNNEIQESLGRATPDTLDESELEA Dmel MNRLFGGPSLNDCITNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKALRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKINIDQIEDIQDDMADMFEQADEVQEALGRTM-PEVDDDDLQA Enthi LNRFIGEPSIDETHTDLDQKIVDLDRQI-RQNIEMSHKTTGAESQRYKQKALMLLKQKKQHEQHRDITERHQMNLENVQFQVDQMKDYKKVYDAMAASNRQMKLISQFDINSIEDVQDSMMNFAEDQQEFGDILSQD--TNMDLNELDD Falba MNRIFGPPSAADTVDVIQVKIDKIDAELKTIQTRLSKMTEGSAKQQLKNKAIMLIRQKRGYEQQKNSMLQTAFSVDQVQMTTENLRLTIDTAQTMKQTAKDMKREYRLDINKIEAIQDDLQDMMDQANEIQEIMGRGVPDYIDEADLES Fomme1 --------------------------------------------SAIEQRALRTLKQKKMYEGQLAQLQQQTFNMESAALATENLRNTMATFDAMKVANKEMKKQYKIDIDKIENMHYDMEDLLEQANEIQETLGRSVPDEIDEADLQA Fusgr1 MNRLFGKPTLNGAISSLDTKLKALNAELGAYQEKLSRMRDGPGKQAMKQKALKVLQRRKAYEAEKDKLESQVWNMEQASNMQDNLKNVMTQVDAMKTTNKELKKQYKIDIDKIERLQDEMADLMDVGNEIQESLARSIPDDVEEDELDA Galma1 MNRLFGKPNLQDAIASIEVKIRKLDGELGRYKEQMAKLRNGPGKNAIQERALRTLKQKRMYEAQIAQLTQQTFNMESAALATDNLRNTMATVDAMQLANKEMRKQYKIDIDKIENIHYDMEDLLEQANEIQETLGRSVPDEIDEADLEA Ganpr1 MKRFFGKVTLQDAIESVDVKIRKLDAELLRYKEQMAKLRDGPGKNAIKQKAMRVLKQRKLYEGQRDQLMQQAFNMEQTAMATENLRNTAITLDAMKTGAKEMKAQYKLNINKITDMQDEMEDLMDQANEIQEELSRSTPEGVDDADLEA Gloin1 MNRLFGKPSLNDAIDAVEVKIKKLDAELAKYKDQMKKMRDGPGKNAIKNKALRVLKQRKMYETQRDQLQQQSFNMEQAAFTTENLRNVISTVDAMQIANKEMQKQYNIDINKIESIQDDMEDLLEQANDIQESLGRTVPEDIDEDDLEA Hisca1 MNRLFGKPTLDSAIASIDVKLAALNAELSSYQSRMAKMRDGPGKNAIRQKALKVLQRRKQYEAQRDQLSQQSWNMEQAGMMQDNLKNVMTTVDAMKTTTKTLKQQYKVDIDQIERMQDEMQDLMEIGNEIQESISRAVPEDVDEAELDA Klula1 MNRIFGEQMMQDSSSQLDTQISQLNFQLSTLQKKISNTKSSMGQKPLRQRALKLLNKRKQLEAMRDQLDSQSWSMSQVQMTTDNLKNTMVTVNALKQTNQALKQQYKINIDKIQDMQDEMMDLIEQGDELQDVLAMQI-DDISESELDA Lacbi2 MNRFFGKPSLQDAIASIEVKVRKLDAELARYKEQMSKLRPGPGKNAIQERALRTLKQKRMYEAQIAQLTQQTFNMESAALATDNLRNTMATVDAMQIANKEMRKQYKIDIDKIENIHYDMEDLLEQANEIQETLGRSVPDEIDEADLEA Lenti61 MNRIFGRPTLQDAIASIEVKIKKLDGELARYKEQMGRLRNGPGKNAIQERALRTLKQKRLYESQLAQLTQQTFNMESAALATENLRNTMATVDAMKQANKELRKQYKIDIDKIESVHYDMEDLLEQANEIQETLGRSVPDEIDEADLQA Malgl1 MQRLFGKPDLQQAIDATQVKISRLDAELGRYRDQMKKMREGPGKSAIQQRAIRVLRQKRMYEAQMEQLVQQSFNMEQSVMVTENLRNTMATVDAMQQANKNLKKTYNINVDKIEQIQDEMEDLMEQSGALQETLARSTPDDIDETELEA Mellp23 QNRIFGKPTLNDAIDSMEVKIRKLDAELIRYKENMKKLRDGPGKTAMQQRAMRVLKQKKLYEGQLEQLQQQTFNMEQAIMTTDNLRNTMATVDAMKQANKEMTKQYKINISQIEAISYDMEDLIEQANEVQESLGRSVPDEIDEDELQA Mnele MNRLFGAPNLTDTIDSIEKKIQKLDVELKRYSDQMKKMRDGPSKNMVKQKALRVLKQKRQYEQQLEGIRNQAFNMEQTNYTTQMLKDTKVSVDAMQTGLKQMKKEYSVNIDKIEDLQDDLADMMEDANEIQEIMGRAM-PEIDDAELEA Monbr MNRLFGAPSLTDMVESIEKKIAKLDIELNKYKKQIQQLKGKPGEKMVRQRAMRVLKQKRTYENQLGQVQQQSFNMEQQNFAIQSLQDTQHTVAAMKEGAKAMKTQFKLNVSQIEDIQDELEDLMEDQNEIQEILARSM-DDIDEGDLDA Morel2 MHRLFGKPTLTDAIDAVEVKIRKLDAELIKYKDQMKKMRDGPAKNSVKTKAMRILKERKLYESQREQLQQQSFNMEQAAFTTENLKNVMTTVDAMKTANQTMKQQYKVNLDKIEQMQDEMEDIMDQANEIQETLGRSVPDDIDEDELEA Mucci2 MNRLFGKPTLNDAIDAVEVKVKKLDAELTRYRDQLKKMRDGPAKKTVQQKALRVLKQKKLYEAQRDNLQQQSFNMEQAQMTTENLRNVMATVDAMQTANKEMKKQYNVNLDKIDQLQDEMEDLMEQANEVQETLGRSLPDDIDEDDLEA Mydma MNRIFGPPNLTDCIESVEKKIQMLDRDLLKYKEQMKKMREGPSKNMVKQKAMRVLKQKKMYENQLENLRNQSFNMEQANFATQTLKDTKTTVDAMKLGVQQMKKEYKINIDQIEDLQDDMEDMLEQANEVQEALGRQM-PEIDDADLDA Neucr2 MNRLFGKPTLTTAISSIDVKLASLTAELSGYQSKLSKMRDGPGKSALKQKALKVLRQRKQYEAQRDQIQSQVWNMEQAQTMQDNLKNTMVTIDALKTTNKQLKKEYKVDIDKIERLQDEMADLLDVGNEIQESLARSVPEDVDEDELDA Orpsp11 MNRLFGAPSLEDAIDSVEVKIRRLDAELSKYKDQMSRMREGPAKNSVKQKAMRVLKQKKMYEQQRDQLMQQSFNMEQTSFATENLKNTVTTVNAMKQANKQLKKQYKVNIDKIEAMQDEMEDLLDQANEIQEALGRSLPEDIDEADLEA Pench1 MNRLFGKPTLEGAISSIDVKLAALNSELSTYQTKMAKMRDGPGKNALRQKALRVLQRRKQYEAQRDQLSQQSWNMEQAGMMQDNLKNVMTTVDAMKTTTKELKKQYKVDVDKIEQMQDEMADLMEVGNEIQESISRAVPEDVDEAELDA Phybl2 MNRLFGKPTLNDAIDAVEVKVKKLDAELTRYRDQMKKMRDGPAKSAVQQKALRVLKQKKLYEAQRDNLQQQSFNMEQAQMTTENLRNVMATVDAMQTANKEMKKQYNVDLDKIDQLQDEMEDLMEAANEVQESLGRSLPDDIDEDDLAA Picst3 MNRLFGKPSLNDAIGSLDVKLSKINAELLTYQQKISRMRDGPGKSALKQRALKLLRQRKQIEAQKDQLELQSWNITQASMTTDNLQNTMITVDAMKLANKQLRKTYKIDIDQIESLQDEMLDLIDKSNELQEALLTTVPDDISESELDA Plicr1 MNRIFGKPNLQDAIASIEVKVKKLDGELGRYKEQMSKLRNGPGKDAIQQRALRTLKQKRMYEAQMAQLTQQTFNMESASLATDNLRNTMATVDAMKLANKEMRKQYKIDVDKIESIHYDMEDMLEQANEIQETLGRSVPDEIDEADLEA Polpo MKRFFGAPTLDEATGGLDDKIRKLDQELAVYRQQIKNTRPGPAQNGIKAKAMRVMKQKKMYEAQRDQLSQQSFNMEQTKFATQSMQDTVTMVSAMKQGAKEMKQQFHINVDDVDSLQDEMQDLLDFNNDLQQSMSRATPDSLDESELEA Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 MNRIFGKPTLQDAIASIEVKVKKLDGELARYKEQMSKLRNGPGKDAIQQRALRTLKQKRMYESQLAQLTQQTFNMESAALATENLRNTMATVDAMKTANKELKRQYKIDIDKIENIHYEMEDLLEQANEIQESLGRSVPDEIDEADLEA Rhior3 MNRLFGKPTLTDAIDAVEGPIKENERRSSKEKRSTKGVTSAETKETASRFTLLIFSLAFRYEAQRDNLQQQSFNMEQAQMTTENLRNVMATVDAMQTANKEMKKQYNVDLDKIDQLQDEMEDLMEQANEVQETLGRSLPDDVDVDDLEA Rhoto1 MNRLFGKPSLADAIDSIEVKIRKLDAELTKYRDQMKKMRDGPGKNAVQQRALRVLKQKKLYESQIAQLQQQSFNMEQASMTTENLRNTMATVDAMKTANKEMKKQYKIDIDKIEAMHDDMADLLDSANDVQEAMSRTVPEEVDEADLEA Rozal11 MNRFFGKPTLNDAIESVEVKVKKLDAELARYKDQMSKMKDGPAKNAIKSKALRVLKQKKLYEGQRDMMMQQSFNMDQTNFALESMKSTVTTVDAMKIAAKEMKTQFAINIDKIDNLQDEIEDLLEQSNEVQEALGRSLPDDVDEDELEA Sacce1 MNRIFGDQLLQESNSQLDTQIAQLNFQLQNIQKNLQ--RSNNKQPSLRKQALKILNKRKQLENMKDSLDSQSWSMTQAQLTNDNLQNTMITINALKQTNNAMKAQYKINIDKLQDMQDEMLDLIEQGDELQEVLAMNL-DDISDAELDA Salro ASRLFGGPSMTEIIASVDKKIAQLDEQLKQCKQKMSKMREGPAKQRVKQQALRILRQRKTYEQQYGKLQQQSFNLEQQNYAVQSLKDTHATVSAMREGKKAMQTEFKININDIEDIQDDMEDLMEDHDEIQEILGRTM-EDVDEGDLEA Schco3 MNRIFGKPSLQDAISSIEVKIRKLDGELARYKEQMSKLRNGPGKNAIQQRALRTLKQKRMYESQLEQLTQQTFNMESAALTTENLRNTMATVDAMKMANKEMRKQYKIDIDKIENVQFEMEDLIEQANEIQESLGRSVPDELDEADLEA Schpo1 MHRLFGTASLTDAIDSVEVKIAKLDAQLSVFQQKIANTRPGPGQTALKQRAMNVLRQKKIYESQLQQLQQQSFNMEQAAMTTESLKNTMATVQTMQETARQLKSQSNVSIEKIEKLQDEIQDYMDAAGELNEVLGQNI--NVDEEELDA Sorma MNRLFGKPTLTTAISSIDVKLASLTAELSGYQTKLSKMRDGPGKTALKQKALKVLRQRKQYEAQRDQIQSQVWNMEQAQTMQDNLKNTMVTIDALKTTNKQLKKEYKVDLDKIERLQDEMADLLDVGNEIQESLARSVPEDVDEDELDA Sphar MDRIFGAPTLSDAIAAIEKKINSLDAELLKYKKQMASMREGAGKNQVKQRAMRVLKQKKL----------------------------------------------------------------------------------------- Spipu1 MNRIFGKPTIGDAIDSVEVKIKKLDAELMKYKDQMKKMREGPAKNSVKQKAMRILKQKKLYEGQRDQLMQQSFNMEQGNMALDNLKNTLVTVDAMKLANKELRGQYKVNLDKIEKIQDEMEDLLEQANDIQETMARSLPEGIDEDDLEA Sporo1 MNRLFGKPSLNDAIDSIEVKIRKLDAELTKYRDQMRKMRDGPGKSAVQQRALRVLKQKKLYEGQIGQLQQQTFNMEQASITTENLRNTMATVDAMKTANKELKKQYKLNVDKIEQMHYDMEDLIEQANEVQESMSRTVPDEVDEADLEA Stehi1 MNRIFGKPSLQDAIGSIEVKIKKLDGELGRYKEQMSKLRNGPGKAAIQQRAMRTLQQKKMYENQLAQLTQQTFNMESAALATENLRNTMATVDAMKTANKELRKQYKIDVDKIENMQFELEDLVEQANEIQETLGRSVPDEIDEADLEA Tapde11 MNRIFGTPSLADAIDAIQVKIHKLDIELQTHQQKISRLR-GAAQESAKKRAIGVLRQKKLYESQLDQLNQQSFNMEQANLTTENMRNTMTTVTAMQAANKTLKKEYKINIDKIERLQDEMSDLIESANELSEVMGRNLGDGIDEEDLEA Thetr MKRLFGPPSLSDTTDGLNEKIRKLDAELLRYKKQMAKMRPGAAKNGVKQRALRVLRQKKMYEQQMDQLMQQSFNIEQTAFAIETAQDTVQTVTAMKEANKQLKKQFALDIDAIEDLQDDMEDLFEQNQDIQEAMARSVAEDFDEEDLDA Treme1 MNRIFGKPNLTDAIGSIEVKIKKLDAELGAFKTQMAKLRDGPGKNAIQQRALRTLKQKRMYESQLMQLQQQTWNMEQAAMTTENLKNTMATVDAMRVANKEMKKQYGLDIDKIETMHYDMEDLIEQANEIQESLGRSVPDEVDEADLQA Trire2 MNRLFGKPTLTGAIASIDTKLKALNGELSAYQEKLSKMRDGPGKQAIKQKALKVLQRRKAYEAEKDKLEAQVWNMEQAQTMQDNLKNVMTQVDAMKTTNKELRKQYKIDIDKIERLQDEMADLLDVGNEIQESLARGIPDEVDEAELDA Umbra1 MNRIFGKATLTDAIDAIEVKIRKLDAELTRYRDQMKKMREGPAKKSVQQKALRVLKQRKLYESQRDNLQQQSFNMEQAQMTNDNLRNVMTTVDAMQSANKEMKKQYNVNLDKLDRLQDEMEDLMEQANEVQESLGRSLPDDVDEADLEA Ustma22 MNRLFGKPSLTDAIDSVEVKIRKLDSELTRYRDQMRKMRDGPGKTAIQQRALRVLKQKRLYENQLAQLQQQSYNMEQATMTTENLRNTMATFDAMQSANKEMKKTYKIDLDKIESMQDEMEDLIEAANEVQETLGRSVPDEVDEEDLQA Walse1 MQRLFGKTSLNDAISSIESKVKKCDQELAQFKQQMNRLRDGPGKRAVQQRAMRVLQQRKVYEGQLEQLQQQTFNMEQAQMTTENLTGTMATVDAMQTANKQMRKQYKIDIDKIDSIQDDMQDLIESATEIQETLGRSVPDEIDEADLEA Zygro1 MNRILGEQMLQESGSNLDTQISQLSFQLQTLQRKISTSRSAAGQRPLRQQALKLLNKRKQLEQMRDQLDSQSWSMSQAQMTSDNLKNTMVTVNALKTTNKALKAQYKINVDKLQDMQDEMADLIEQGDELQQVLASNA-EDVDEDELDA [Cluster2052.fasta_al_trimmed; alignment length = 376] Allma1 KVYRVGTLPEWLTERQDFEFPEASYRIKLTRDGKYAMATGVYKPQIRVYEFAEMAMKFDRHSDVENINFVILSDDWT-KSVHLQADRSLQFHTQFGIHYTTRIPKFGRDLQYSCDLLVGGASDIYRLNLEEGRFLNP-VEFWDPR-IRSRIARIEISALDG-LHLGVGTSSGHVLLYDLRHPAPKDHQYGLEIRNVVISTDRKIIRMWNRESTSIEPDINDVS-GLLFVAGEAVQMHTYLVPDLGPAPHFAAFLENLTEEMA--EL-YDNYKFVTRKELKKLGLE-QVVGAAKAYMHGYFIDQRLYERAKLIANPFA-FEEYKQQLIKEKLEAKRGSRIKVNSNLAAKLDDRFKAVFENPEFAIDESSDAFKLLNP Ashgo11 SVYQVSSLPDWIAKKQDFEFSEASNKIKVSPDGQYAMATGTYKPQIHVYDFANLSMKFERHTDAENVDFVILSDDWT-KSVHLQNDRSIQFQNKGGIHYTTRIPKFGRSLCYNCDLYVGASGELYRLNLEQGRFLNP-VEFWDPR-ARTRVTSLQVTTSDG-LNFACGTSSGYTYLYDLRMSDPKDQGYGFEIKKILLTCDKRIAKIWDRNTTSMEPDINDIT-GLFFTANEGIPMHTYYIPALGPAPKWCSFLDSITEELE--EV-YSNYRFITKEDVRKLNLA-HLIGVLRAYMHGYFINTELYDKVCLIANPNT-YRDEREREIRRRIEKERESRIKVNKGLVDKLDERFKEMFEDEDFLVDEDDYDYKQLNP Aspfu1 PVYTISPLPEWLARRQDFEFEEASQCIRVSEDGEWVMSTGTYKPQIHTHYLPQLSLSWARHTDALNTTFLLLSSDYS-KSIHLQSDRSLEFHTPSGCHYRTRLPRYGRDLVYSTEALVPAVGEVFRLNLEMGRYMRS-VELWDPR-AKGRAGVLEITALSG-LTFATGSSNGLIHLYDLRSPVPKDQGYGFPVHTLILSSDKKIIKIWDPRDTSVELDINSVS-GMLLTANEGRQQHAFFIPQLGPAPRWCSFLDNLVEEMA--EV-YDNYKFLTVPQLKTLNLD-HLIGLLRPYMHGYFVAQRLYEEARLITNPYI-WEEERAKRVKEKIDKERESRIKVNKKLAEKLDSRFAKMFEDEEFAVDETSREFQLLNP Aurde31 KVYTVNSLPDWLTRKQDFEFPEASYRIKVTRDGHHAIATGTYKPQVKCFDLDQLSQKFERHSDAENVDFALLSDDWT-KSIHLQADRTLELHTQSAAHYKTRIPRFGRAIGYSCDALVAAAGEIYRLNLDQGRFMTS-VEFWDPR-SRDRLAVLACTALDG-LTLAIGTHAGFTYVYDLRAARPKDQGYGLPVHRVLVSADKKVIKLWDRDAASITPDLNDVT-GMLMTANEGIPMHAYYIPALGPAPRWCAFLDSLTEELE--DV-YEDFKFLDRAELERLGLD-ALLGALRPYMHGFFIKLALYDAARVIADPFV-YEDARRKKVQEKMDKLADSRIKVNAALADRVDSRFSAVFEDPEFAVDEQSREYQLLNP Batde5 KIYSITAIPDWAVQKQDFEFPEASLRLQMTRD-------GVYQPQMRVFEVSQMAMKLDRHTEAENVQFEILSDDWT-KSVLLQSDRTIELHSQFGLHYKTRVPKFGRDLSYSCDLMIVGSSEVWRLNLEQGRFLNS-VEFWDPR-ERSRIGRLEIESLDG-LSFCVGSKTGQIVMYDLRRPTPKDHQYGFPIKKLILSADSKIIKIWNRMDTSIESDINDVS-GLVMLANEGVQIQSYYIPAMGPAPRWCPFLDNLTEELE--EM-YDDYKFVTRKDLANLSLD-HLVGLLKAYMHGFFVDLRLYEKAKAIANPFE-FEDHKRRLVQQKIETQRKSRIKINRNLAAKLDDRFAALFQDEEFQVDEESHEYRLHYP Botbo1 KIYTVNSLPDWLTRKQHFEFPEASIRIKTTRDGHHALATGVYKPQMRVYDLDQLSLKFERHSDSENVDFLILSDDWT-KTLHLQNDRTIEFHTQGGLHYRTRIPRFGRSIAYSCDTLISAAGEIYRLNLDQGRFLNP-VEFWDPR-SRSRVGLLSVTALDG-LSLAVGTSTGHTLLYDIRSPRPKDQGYGLPVKTVVISADKKVVKIWDRNSASVTPDINDVS-GLVMLANEGIQMTTFYIPQLGPAPKWCSFLDNITEEME--DL-YEDYKFVERSELASLGLD-HLIGTLKPYMHGYFLSLRLYDAARLIANPFA-YAEHREKTIKSKMEKLAENRIKVNKALAERIDPRFKELFENPQFEVDERSREFGMLNP Botci1 PVYTISPLPDWLARKQDFEFEEASSCIRVSEDGEWVMSTGTYKPQIHTHYLPHLSLSFARHTTTLNHSFILLSNDYT-KSLHLQTDRRLEFHTQGGCHYQTRLPRYGRDLVYSTEALIPAVGEVYRLNLEIGRYMKP-VEFWDSR-SKARVGILGITALSG-ISIATGSSEGIVQLYDLRRPVPKDQGYGYAIKTLILSADKRIIKLWDETDTSVEPDINSVS-GMLLTANEGKQQHAFFIPQLGPAPKWCSFLDNMVEEMA--ET-YDNYKFLTVPELKALNLG-HLIGLLRPYMHGYFVASKLYEQARLIANPYV-WEDERIKRVKEKVEKERASRIKVNQNLVDKVDSRFGKLFEDEDFAVDERSREFQALNP Caeel KIYNLSSLPEWMSSRQDFEMPDVSNTVNITPDGKYVWASGNYKPWLRCYDLNNLSLKFERGLDADVIKLIPLSDDYS-KVVILEEERWIEMHAMLGRYFRMRMPCQGRDMALSSDLYLVGSKEVYRFNLEQGCWLTP-VEAWDHR-DKSLCGTLAVTSVDP-LHIGVGTSTGQILIYDLRARRPKDHNNELPINKLVASMDSRMMKLWHEEDAAIENPLNDFS-GMFFFANEAPKMLQYFIPQLGPAPKWCSYLENLTEEME--EV-YDNYRFVTKKQLDDLGLS-GLIGVLRAYMHGYFIDARLYNKAQTQMQPFA-YEKYKDEKIKSMIADEREESAAVNKALAARLDDRFKKLFESEDFEVDETSEQF-LKNA Canalb1 SVYQVSSLPDWIDKKQDFEFSEASNKIKVTNDGQYCMATGTYKPQIHVYEFANLSLKFDRHTNVENIDFLILSNDWT-KSVHLQCDRSIEFQTAGGVHYRTRIPKFGRCLTYNCDLIVGSSSELYRLNLDQGRFLSP-VEFWDPR-SKQRAGKLGITSLDA-LNFACGTSNGQTLLYDLRASEPKDQGYGYDIKKIILTSDKRIVKIWDHTNASMEPDINDIS-GMFFMANEGMPMHTYYIPNLGSAPNWCSFLDNVTEELE--EI-YSNFKFITRDEVVKLNLT-HLIGVLRSYMHGFFINTELYDKVNLISNPNS-IYDQRKREIANKINEERKSRIKVNKDLVNKLDDRFREMFENPDFEIDEESHEYKQLNP Cangl SVYQVSSLPDWIAKKQDFEFSEASNKIRVTKDGNYAMATGTYKPQIHVYDFANLSMKFDRHTDAENVDFVLISDDWT-KSVHLQNDRSIQFQSKGGIHYTTRIPKFGRSLTYNCDLYVGASSELYRLNLEQGRFLNP-VEFWDPR-ARTRAAKLQVTTSDG-LNFACGTSTGYSYLYDLRTSEPKDQGYGFDIKKIILTCDKRIAKIWNKDTASMEPDINDIS-GMFFTANEGIPMHTYYIPTLGPSPRWCSFLDSITEELE--EV-YSNYRFITRDDVKKLNIT-HLVGVLRAYMHGFFINTELYDKVSLIANPNA-YKDEREREIRRRIEKERESRIKFNKDLVEKIDDRFKEMFEDEDFKVDENDYDYKQLNP Capow KVYNVSSMPEWISDRQDFEMPTAATNLRASKDGRFLLATGVYPPRIRCYELSELAMKFERYLQSEPVKFEMLSDDYT-KIACLSSDRFLEIHAQYGTHYKTRIPRFGRDLAYATELIAVGDSDIYRLNLELGRFMTP-IECWDPR-SRTCHGQLEVTSIDG-LSMAVGVSTGQVLLFDVRSDQPKDHQYGFPIKRIMVTADTKIIKIWERNTTSIEPDINDAS-GLILTANEDKKMQAYYVPSLGNAPKWCSFLDNLTEELE--EV-FDDYKFVTRKDLEVLGLT-HLVGLLRAYMHGFFIDLRLYNRAKAIAEPFA-YEEYRKSKIKEKIDAQRANRIKVNKGFAKLLDDRFGAMFKNPEFEIDPESETFRILHP Catan2 KVYRVGTLPKWLASQQDFEFPQASYRIKLTRDGKYAMASGVYKPQLRVYDFSEMSMKFERHSDVENVNFVILSEDWT-KSVHLQADRTIEFHSQFGRLYTTRIPKFGRDIQYSCDVLVGGASDVYRLNLEQGRFLNP-VEFWDPR-VRSRIARLEISALDG-LHLGVGTSSGHVLLYDLRSPTPKDHQYGLEIRHVVISADRKIVRMWNNASTSIEPDINDIS-GLLFIAGEAVQMHTYLVPDLGPSPRFAAFLDNLTEEMA--EL-YDNYKFVTRNELKKLGLE-MVVGAAKAYMHGYFIDARLYERARVIANPFA-FDEFKKQMVKEKLEAKRASRIKVNQALAEKLDDRFKKVFEDDEFYVDETSETFKLLNP Cioin KIYNLSSLPEFITDKQDFGMPTVSTTVKMSPDGQYIFATGTYKPRVRCYDVNHLSVKFERCLDSEAVAFDILSEDYS-KLVFLLSNRTIELHTQQGRHYSVRMPKFGRDLCYNCDLMLVGAGEIYRLNLDQGRFLKS-VECWDPR-SRQAVGVLKVTCLGP-LNLAVGTSTGQVMLYDIRSNRPKDHRYELPINSIVISSDSRAVKLWKENTTAVEMDINNMS-GLFFLANESPKIHSYFIPMLGPAPKWCSFLDNITEEME--EI-YDDYKFLTQKEVQTLGLS-NLVGLLRAYMHGYFIDIRLYHKAMAVANPFA-YKEYRKRKIEERVEEARANRVKVNRHLADRLDPRFKSMFEDPNFQVDEESEEFKLLNP CocheC53 PVYTISPLPEWLIRKQDFEFEEASQCVRVSEDGDWVMSTGTYKPQIHVHYLPHLSLSFARHTNTLNQTFHLLSSDAT-KSVHLQQDRCIEFHTGGGLHYASRIPRYGRDLIYSAECLVPSVGECFRLNLEVGRFMRS-VEYFDSR-TRTRVGILETTALNG-LEMAVGDSNGITHLYDLRSPKPKDQGYGFAIKNIILTADQRVIKIWDAKDTSVQPDLNHVT-GMLLTANEGRQQHSFFIPQLGPAPRWCHFLDNIVEEMA--EV-YDNFKFLTMDQLKQLSLD-HLVGLLRPYMHGFFVAQKLYEEARLISNPDL-WQEQRAKSIAEKINKERESRIKVNRKLAEKMDPRFAKMFEDPEFEIDEQTREFQQLNP Coere1 KVYTVSKLPDWLIRRQDFEFPEASLRIKVTPDQSHCMATGVYKPQIRVFDFSNVSMKFDRHTDAENVNFMLLSDDWT-KSVHLQSDRSLEFHNEGQMHFRTRIPRFGRDLAYSCDVLVGGASEVWRLNIDQGRFMTP-VEFWDPR-ARNCIGTLEISAMDG-LGVAIGTSSGHVMLYDLRQSRPKDQQYGLPIKTLIMSADSRIIKLWSVDSTAIEPDINDVS-GIIFVAGECSEIQSYFIPQLGPAPRWAHFLENLTEEME--QV-YDDYKFVVRKELEALGLS-HLIGVLKPYMHGFFVDLRLYERAKSIANPFA-YEEYRVRRVQQKLDEARESRIKVNRALAMRLDNRFKDMFSNPEFEVDEEEDEFKQLHT Conco1 KVYTLSQLPHHLLKKQEFGFAEASNRLKISRDKKFIMATGTYKPMMKVYDLGEMSLKFERNTNAENIAIEILSDDWT-KSCHLQADRFVEFHTTGECRFKTRIPKFGRDLGYSCDLFVASSGEVYRLNLEQGRFLNP-MEFWDPR-SRSKVTSIDVTSLSG-LQMAVGLAGGKVLLYDLRGNQPKDHQYNLPIKRMLATADSKILKIWDVPNTSLEPDINDFS-GMLMVANEGPEMHTFYIPQLGPAPKWCTFLENITEELE--EI-YDDYKFVTRSELSKLGLE-HLLGVLRGYMHGFLMDIRLYEQARLIANPFE-IEEYKTRRIADKLASERKSRVKVNQHLLDKADDRFARLFEDADFEVDTKSREFKLLNP Conpu1 KVYTVNSIPDWLTQKQGFEFPAAAVRLKTTRAGHHVVATGAYKPQVRVWDLDELGMKFERHCEAENVDFEILSDDWT-KLLLLQNDRTVELHAQGGLHHRTRIPRFGRAVAYSADALFATSGEIYRLNLAQGRFLAP-VSFVDPR-ARAPVGRLGVTALDG-LSYALGTGSGHVLVYDVRMARAKDQGYGLPIRRVVMSADRKVVKVWERGNFSITPDLNDIS-GLLLTAHEGPGMGAFYVPALGPAPRWARFLENITEEME--GV-YEDYKFVERSELKTLGLE-HLVGALKPYMHGYFLALELYDTARLIANPFV-YAEHREKLVRQRMDKLAESRIKVNKALAEKIDPRFKALFENPAFTVDEESREYALLNP Copci RVYTVNSLPDWLTRKQGFEFPEASNRIKVTRDGRNVIATGTYKPQMRVWDLDQLSLKFERHSDAENVDFVILSDDWT-KIMQLQNDRTVELHTQGGLHYKTRIPKMGRSLAYSCDAIVAATGEVYRLNLDQGRFMTP-VQFWDHR-SRTSVGTLSITAIDG-LSYAIGTSSGHTLLYDIRAANPKDQGYGLPIKDVVLSADKKVIKIWDRNSASITPDLNNIS-GLLLTANEGIQMCTYFIPQLGPAPRWASFLENITEEME--DV-YEDYKFITRDELNALGLD-NLIGTLKPYMHGYFVSLKLYETARLIANPFA-YAEHRERTIKEKMEKMAETRIKVNKMLAEKIDPRFAKVFEDPDFAIDVNSREYALLNP Croqu1 KLYTVNQ-PDWLGSTQDFDFPEASNKIKSTSDGRYLIATGTYKPRMKVFELDELAMKFDRVTDSENIDFCILSTDWT-KTIHLQTDRTLDLHTQTASHYRVRIPKHGRALAYSCDAICGGAGELWRLNLEQGRFLAP-VEFWDHR-ARSRAGRLSVTALDG-LTTAVGTSTGHTLLYDLRAATPKDQGYGLPIKKIVATADSNVVKIWSRHTVSVNPPINDMS-GLIFLANEASPMTGYFVPALGPAPRWCRFLENMTEEME--EI-YDDYKFVSDSELKALALD-HLVGALRPYMHGYFVDLRLYAKAKAIANPFA-YIEHRDRLVKQKLEKEQESRIKINKEFAQRIDSRFKDLFTNEDFEIDEYSREYAAVNP CryneH991 KVYTVNSLPSWLAVKQDFTFPGSSIKIKTTEDGQHAIATGTYKPMMKVWDLEALTVKFERVTDAENVDFVILSSDWT-KTLHLQRDRSLQLHTQMGLHHTIRLPIYGRSLAYSADALVGCTGEVFRFNLEEGRYMTP-VEFWDPR-SRSALTRLSITALDG-LSLAVGTSTGHTLLYDLRSPTPKDQGYSEPIRKVVVSADSKVIKIWDKNQLSLHPSLVDLS-GLMLVACDAPQLSSYYIPDIGPAPKWASFLDSVTEELAD-DA-YADYKFVDKAELETLGLT-HLIGALKPYMHGYFLSLKLYTTARLIANPQS-YSEYRDRIVNEKLKAKSESRIKVNKALAERVDPRFKELWENPEYEVDEESREFALLNP Crypa2 PVYTVSPLPDWLARRQDFEFEEASACVRVSGDGQWIMSTGTYKPQIHVHDLNQLSLSWARHTTSLNQSFVILSPDAS-KSLHLQTDRKLEFHTLGGCHHEIRLPRYGRDLIYSTEALVAAAGEVFRLNLEHGRFMKS-VELIDPR-VRSRVAVLEVTSLTG-LSLVTGTSQGVCSVFDLRRPVPKEQGFGFGIKNIILSADKKIIKIWDDTTTSIEPDLNFVT-GTLVTANEGKQQHVFHIPALGSAPKWCGFLDNMVEEMT--ET-YDNYKFLTKPELKSLSLD-HLVGMLRPYMHGYFVDTKLYEQARLVANPYV-YEDERQKRVQEKVEKERASRIKVNQRLADKIDNRFAKLFEDEEFVVDETSREFKIINP Debha1 SVYQVSSLPDWIAKKQDFEFSEASNKIRVSPDGQYAMATGTYKPQIHVYDFANLSLKFDRHTDCENIDFLVLSNDWT-KSIHLQNDRSIEFHTKGGIHYRSRIPKFGRSMAYNCDLLVGASGELYRLNLDKGRFLNP-VEFWDPR-SRQRAAKLEITATDG-LNFACGTSNGKSLIYDLRTSTPKDQGYGYGIKKIILTTDKRIAKIWDRNDASMEPDINDIS-GMFFMANEGIPMHTYYIPNLGPAPRWCSFLDNVTEELE--EV-YSNYRFITRDQVTKLNIA-HLIGVLRSYMHGFFIDTELYDKVNLIANPNS-YQDQREREIRKRIEKERESRIKVNKDLASKLDDRFKEMFENPEFAIDEQSHEYKQLNP Dekbr2 SVYQVSSLPDWIARKQDFEFSEASNKIRVTNDGQYVMATGTYKPQIHVYEFSNLAIKFSRHTDAENVDFTLLSDDWT-KSIHLQNDRSLEFQIKGERYYKTRIPKYGRCLAYSCDLYVGASSEVFRLNLERGRYMRP-VEFWDPR-AKQRVIKAEITCVDA-LSFACGTSNGVSLLYDLRNSKPKDQGYGFGIKDIILTSDKKIAKIWNRNTAAMEPDINDVS-GMFFMATESIPMHTYYIPALGPAPKWCSFLDNITEELE--EV-YSNYRFITRDDVKKLNIE-QLVGLMKAYMHGYFINTELYDKVKLIANPTA-LEDEREREVKKRIEKERESRTKVNKSIVGHLDERFKEMFEDPAFQVDESNLDYQQIN- Dicdi KIYNVSSLPEWLSENQDFSFETSSQRVRISQDGQYIMATGIYPPQFKVFELSQLSQKVSRNLDCNVVTFEMLSDDYS-KPVFLRDDRYIEFHAKFGSYFKTRIPKLGRDMTYSCDLYITASDEVYRLNLEEGRFLAP-IECWDPR-VRTMVSTISITAGDG-LLLGLGTSNGGVLMYDIRSASPKMHQYQLPINSIIMSSDAKIFKSFEKDTMVLEPPITDVS-GLLLMPGNTQKIQTYYVPALGAAPRWCSFLDNLTEELE--EV-YEDYKFITRDEVAKLDIE-NLIGYLKAYMHGYFIHIKLYNKVVMSKNPTN-YEDLRKQQIKDKLAEKNQTRIAVNAKLAERLDPRFKAMFENRDFEQDEGSEAFLRVNP Dmel KIYNLSSVPDWLTDRQDFDMPGVCTSIRMSPDQQYILATGTYKPRVKCFEVSNLSIKFERCFDAEVTTFEVISDDYS-KMVFLQCDRYVEIHAAHGRHYRLRIPRFGRDMKYSCDMFIVGVGDIFRLNLERGQFLQP-VEAWDPR-TKQRCSTLSVTALNG-LHMGVGTASGHVLIYDIRAKQPKNHLNRLPIKRLVYSLDEATLKLWDEQTAYVESSFNDFT-GMFFVAQEDVKMMTYYVPAMGPAPRWCSFLDNLTEEIE--SV-YDDYQFVTAKELAELGME-HLVGLLKGYMHGYFMDARLYNKAKAVVEPFA-FDRFRKDKIRQEIESERKSRLKVNKELALKIDSRFKAMFENADFEVNKSAEEYRLLAP Enthi KVYNLTTLPQWLSQKQDTEFPVNSQNVKFSPDGQFLGATGMYPPRIRMFELDQLSQKFERNLDAEITKFEFLEEDYS-KLMFLLTDKTIEFHNKGGIQCKIKVPKTGRDFKYNCNTYI-ATPNLDIINLYEGKFYES-VSVIDPM-TEEEVSVLSIDVTDGNLQMTVGTSNGNVLTYDLRSSKPSYHQNRIPIVKTLVTADANIVRFSNKSNVPLEAVITDVS-GLCVLAGDFSKLQIYYIPSLGIAPSWCSFLENLTEELE--DV-YDDFHFVTKQELHDLGMD-SFIGYLRPYMHGYFMHIKLYQRAMALK--------------------------------------------------------------- Falba KVYHVTSIPEWIAIQQDFEFPTSAARLKYTPDGSHLFAIGVYKPRLRSYDLGQLSMRFERHMDCEATQFQFLSDDWT-KLAIMQADRTIELHSQGGLYYRTRVPRFARDMTYTCDLLIVGDSDVWRLNLDQGRFLKS-VEFWDSR-QREAVGSLEITALDG-LTYAVGTSSGHALLYDLRMSSPRDHQYGFPVTDIIVSSDKKSIRVWNKDTCSIEPDINDVS-GLILTAQEEPRMHAYYVPELGPAPRWCAFLDNITEELE--EV-YDDYKFVTESTLAQLGLE-HLVGMLRAYMHGYFMDARLYSRAMAVANPFA-YEEYRAKQIQEKIEKDRESRIKVNRALAESLDSRFARMFQDEAFEIDTASEEYKLLHP Fomme1 KVYTVNSLPDWLTRKQEFQFPEASNRIKTTRDGHHAIATGVYKPQMRAYDLDQLTLKFERHTDAENVDFIILSDDWT-KTLHLQADRSIELHTQGGFHYRTRIPRFGRAINYSCDALVGASGEVYRLNLDQGRFMTP-VEFWDPR-SRSRVGLLSVTAIDG-LSYAIGTSTGHTLLYDIRSPRHKDLGYGLPVKNVVLSADRKVIKIWDKNKVSITPDINHVS-GLLLLANEGIQMTSYYIPQLGPAPRWCSFLDNITEEME--DV-YEDYKFVEKDDLSRLGLD-HLVGALKPYMHGYFLSLRLYDAARAIANPFL-YEEHRAKRVQEKLDKLAESRIKVNKVLAQRIDPRFSALFENPEFEVDEESREFNLLNP Fusgr1 PVYTISPLPDWLARRQDFEFEEASNCIRVSEDGGWIMSTGTYKPQIHVHNLSQLSLSFARHTNALNHSFELLSSDYS-KSIHLQTDRRLEFHTPMGCHYEVRLPRYGRALVYSTEALIPSVGEVFRMNLELGRFMKS-VEFWDPR-SKSRVAMLEVTALTG-LSIVTGSSTGMMQIFDLRRPVPKDQGYGFAVQKLILSADKRIIKLWDEQTTSVEPDINDVT-GMIMTANEGKQQHAFFVPQLGPAPKWCAFLDNMVEEMA--ET-YDNYKFLTLPELKQLSLS-HLVGLLRPYMHGYFVASKLYEQARLIANPYV-WEEERTKRIKDKVEKERASRIKVNQKLVDKLDDRFNKMFEDEAFQVDENTGEFRALNP Galma1 RVYTVNSLPDWLTRKQGFEFPEASNRVETTRDGHHVIATGTYKPQMRVWDLDQLSLKFERHSDAENVDFVTLSDDWT-KSIHLQNDRTIELHTQGGFHYRTRIPRFGRSLAYSCDTYITASEEVYRLNLDQGRFMTP-VQLWDPR-SRSRVGVLSVTAIDG-LSYAIGTSTGHTLLYDIRAANPKDQGYGLPVKNVVLSADKKVIKIWDRNTASITPDLNHVS-GLLMTANEGIQMATYYIPQLGPAPKWASFLENITEEME--DV-YEDYKFVERSELKSLGLD-HLVGALKPYMHGYFLSLKLYDTARLIANPFA-YDEYREKMVREKMEKMAETRIKVNKALAEKIDPRFAKVFEDPAFAIDESSREFALLNP Ganpr1 KVYKLTALPDWLAKQQDFGFPEACVRIKPTRDGKHIVGTGVYKPQMRVWELSDLSLKFERHTDCDTIQFELLSDDWT-KSVLLQSDRTLEFHGQGGIHYKTRIPKFGRDLAYSCDLFISSSSSVYRLNLNRGTFLPP-AEFWDPR-ARQRVASLSITALDG-LHMAVGTSTGTILLFDLRNPSPKDHGYSEPITSIVVSSCRRAVKVWNRDSATIEPRVNDATCGMILAATESQYVETFYVPELGPAPRWASFLENLTEEME--EVGYDDYKFVTRKELADLGLD-HLIGVLRAYMHGFFVDLRLYQRAKSIANPFA-FDEYRRKQVEERLAKEKTTRIKVNRKLAERMDARFKALFEDEEFQVDEESAEYILHHP Gloin1 KIYTVSSIPDWLERKQDFEFPEASLRIKSTRDGCFIMATGVYKPQIRVYEYSEMSMKFDRHTDSENVNFVILSDDWT-KSVLLQNDRTIEFHTHGGIYYKTRIPKFGRDLVYSCDLLIGASSEVYRLNLNQGRFLNS-VELWDPR-SRSRIGLLQVTAMDG-LSLAIGTSTGHILLYDLRSSKPKDHQYGYPIKKLVISADSKIMKIWDKDNTSIEPDINDFS-GLIFIANEGIQIGAFYIPSLGPAPKWCSFLDNLTEEME--EI-YENYKFVTRKELETLGMD-QLIGVLKPYMHGFFVDLQLYEKAKLISNPFA-YADYREKIIKEKLEKERESRIKVNKELASRLDDRFAELFTNPEYEIDEQQN---LLHP Hisca1 PVYTISPLPEWLARKQDFEFEEASQCIRVSEDGQWVMSTGTYKPQIHTHYLPHLSLSFARHTVSLNTTFLLLSSDYS-KSLHLQADRSLEFHTPSGCHYTTRLPRYGRDLIYSAEALIPSVGEVYRLNLEQGRYMKA-VELWDPR-ARARAGILEITALSG-LTLATGSSQGLVHLFDLRSPTPKDQGYGYPIHTIILTSDKRIIKIWDARDTSVEPDINSVS-GMLLTANEGRQQHAFFIPQLGPAPKWCAFLDNIVEEMA--EV-YDNFKFLTVPQLRSLNLD-HLIGLLRPYMHGFFVAQRLYEEARLISHPFV-WEEERAKRIKEKIDQERESRINVNKKLAEKLDSRFAKLFEDEDFAVDETSREFRELNS Klula1 SVYQVSSLPDWIAKKQDFEFSEASNKIKVTPDGNYVMATGTYKPQIHVYDFSNLSLKFERHTDAENIDFCILSEDWT-KSVHLQNDRTIQFQNKGGIHYTTRIPKFGRSLAYNCDLYVGASSELYRLNLEQGRFLNP-VEFWDPR-SRSRVAKLQVTCSDG-LNFACGTSNGYSYIYDLRTSEPKDQGYGFAVNKIILTCDKRIAKIWNKNDASMEPDINDIT-GMFFTANEGIPMHTYYIPNLGPAPRWCSFLDSITEELE--EV-YSNYRFITKADVKKLNLT-HLIGVLRAYMHGFFINTELYDKVALIANPNS-YRDEREREIRRRIEKERESRIKVNKMLVDKLDDRFKEMFEDDAFQVDEDDYDYKQLNP Lacbi2 RVYTVNSLPDWLTRKQGFEFPEASNRVKTTRDGHHVIATGTYKPQMRVWDLDQLSLKFERHSDAENVDFVILSDDWT-KSIHLQNDRTIELHTQGGFHYRTRIPRFGRSLAYSCDAYFSASGEIYRLNLEQGCFLNP-VQFWDPR-SRTSVGILSVTAIDG-LSYAVGTSTGHTLLYDIRAAKPKDQGYGLPIKNVVLSADKKVIKIWDRNSASITPDLNDVS-GLLMTANEGIQMVTYFIPQLGPAPRWASFLENITEEME--DI-YEDYKFVERNELKTLGLD-HLVGTLKPYMHGYFISLKLYDTARIIANPFA-YAEHREKVVRDKLDKMAETRIKVNKALAEKIDPRFSKVFEDPEFAIDENTREFALLNP Lenti61 KVYTVNALPDWLTRKQHFDFPEASNKVKTTRDGHHAVATGTYKPQIRVWDLDQLSLKFERHTDAENVDFVMLSDDWT-KSIHLQNDRSVELHTQGGFHYRTRIPRFGRALAYSCDALFAASGEVFRLNLDQGRFLNP-VELWDPR-SRSRVGILSVTAIDG-LSYAIGTSTGHTLLYDIRSARHKDQGYGLPVKKVVLSADKKVIKIWNRNTTSITPDINDVT-GLMLLANEGIKMTTYFVPQLGPAPKWCSFLENLTEEME--DA-YQDFKFIDRAELAKLGLD-HLVGALKPYMHGYFVSLQLYDAARVIANPYA-YAEHRERMVQEKMDKLAETRIKVNKALAEKIDPRFAAVFQDPEFQVDENTREFALLNP Malgl1 RVYSVSSLPDILRRSQDFEFPVASNKIRCTNDGMHIMATGSYKPQIRVWECEQLSLKFERHTDAENVDFL---------SLHLQSDRSLELHNQGGMHTRVRLPRFGRALAYSADALVGAVGEVYRLNLDQGRFLSP-VELWDPR-MRRQAGSLSVTSLDG-LNLAVGTNTGHVLLYDLRMDKPKDQGFGLPIRSLVLSADAKVIKIWDKQSVSVAPNLNQVS-GLLMAAVEATQMAAWYVPALGPSPRWCSFIDNITDEIEMTDA-YEDFKFVDQAELERLELT-HLIGLLRPYMHGYFLALKLYERARLLAHPKA-FDEAKQRAIQAKLEREAESRVQVNRPLAEKLDDRFKELFTNPEFQVDESSREYALLHP Mellp23 KLYTVNQ-PDWLGSTQDFDFPEASNKIKSTSDGRYMIATGTYKPRMKVFDLDELAMKFDRVTDSENIDFCTLSTDWT-KTIHLQTDRTLDLHTQTASLYRVRIPKHGRALAYSCDALCGGAGELWRLNLEQGRFLAP-IEFWDHR-ARARAGRLSVTALDG-LTVAVGTSSGHTLLYDLRAAMPKDQGYGLPIKKIVATADSNVVKIWSRHTVSVNPPINDMS-GLIFLANEASPMTGYFVPALGPAPKWCRFLENMTEEME--EI-YDDYKFVSDSELKALVLD-HLIGALRPYMHGYFVDLRLYAKAKAIANPFA-YIEHRDKLVKEKLEKQQESRIKINKELAERIDSRFKDLFTNEDFEIDEFSREYAAVNP Mnele KIYNLTSIPDWLSDRQEFEMPISSQKIGITPDKTHIYVSGVYPPRLRCFDTKQLSMKFERGMDHEVVAFHILSDDWK-KIVLLQSNRYIEFQTQDGIYYKTRIPTFGRDMCYAAELFIGASGKVYRLNLCKGTFMNP-VECWDPR-SRTRSAILNITCVKI-LELGVGTEEGQVMLYDIRSTKPKDHYYEKPINSIVISACSRSFKVWHKDTTAIESDICDVS-GMFFFANEGQKMKTYFIPSLGPAPKWCWFLDNLTEELE--EV-YDDYKFVTNEELDSLGLT-HLIGYLRAYMHGFFIDMKLYREVKEIVNPFA-FEEYKKGLVDQKLQSQMRDRVRINKSLALKDDDRFGSLFSNPDFEVDEESEQFKLINP Monbr RVFNLTALPSWLSEKQDFEMPTAADCIRVSPDGEYIMAAGTYKPRIRCYDLDQMSLKFERHLNCEVVDMAYLSDNYS-KQVFLMADRYVEVHASYGYHHRTRTPKNGRSIAYTCDLYVGATGEIYRINLEQGRFLKS-VECFDPR-ARERIGVLAISTMDN-LTLGVGTTGGQVLLYDIRAAEPKDHSYGLPIKRIVLAADQKVIKIWKRESTAIEADINDMS-GMFFVGGEQSKMMIYFVPSLGPAPKWCHYLDSITEELD--DV-YDDYKFVTREELDALGLS-SLVGLLKAHMHGYFIDVRLYNEAKDASNPFA-YEEYRQRLIRKKLEEGTESRLKINRALAKRL------------------GWSHRLYSP Morel2 KIYTVSSIPDWLARRQDFEFPEASLKIRTTRDGKYVMATGVYKPQMRVYEYSEMSMKFDRHTDAENVDFQILSDDWT-KTVHLQSDRSIEFQAQGGLHFKTRIPKFGRSLTYSCDLLVTGSSEIYRLNLEQGRFLNS-VEFWDLR-VRGRVGILSISALDG-LSMAVGTSTGHVLMYDLRSNVPKDHQYGFPIKSLIVSADCKIIKIWDRENTSIEPDINDVS-GLMFVANEGIQMQSYYIPSLGPAPKWCSFLDNLTEELE--EI-YDDYKFVTRKELSSLALD-HLVGVLKPYMHGFFIDLRLYEKAKAIANPFA-YTDYREREAKEKLAKESGSRIKVNKQLATKMDNRFADLFTNPDFQVDEGTNEFKLLNP Mucci2 KVYTVSSIPDWLVRQQDFEFPEASNKIKTTRDGKYVVATGTYKPQMRVFEFADMSMKFERHTDAETLNFEILSEDWT-KQALLQNDRSVELHSQGGIHYRTRIPKFGRDLAYSCDLMVTASGEVYRLNLDQGRFLNS-VELWDPR-SKSRVGLLEVSALDG-LTMGVGTTTGHTLLYDLRSSVPKDHQYGFPIKTIVIVADCKIVKIWDRASTSIEPDINDVS-GLIFTANEGIQMGSYFIPQLGPAPRWASFLENLTEEME--EI-YDEYKFVTRKELTALGLE-HLMGVLKAYMHGFFVDLRLYEKARLIANPFA-YDDYRERAVKDKIEKERGSRISVNKALAKQLDSRFADLFEDPDFQVDEKSKEFQLLHP Mydma KVYNLSSLPEWISDRQDFDMPTSSNCVQVSPDGQYIITTGVYKPRLKCFQVDELSLKFDRCFDSECIKFEFLSEDFS-KLVLLQADRYVEMHAQYGRYYRTRMPKFGRDIAYSCDLYLVGDGEVFRLNLEQGRFLQP-VVCFDPR-SRLKIGTLSVTALNG-LEMAVGTSNGSIMIFDIRSNKPKNHLYELPIKNIVLSTDSKILKIWDHETTSVEPTINDMS-GLIFLANESSKNSVYYIPALGQAPKWCSFLDNITEELE--EV-YDDYKFVTDTDLDNLGLS-HLRGLVRAYMHGFFIDMRLYHKAKSIVEPFA-YEEYRKNRIKTKLEEERSSRIKINRHLAEKLDDRFGAMFMNKDFQVDMESEEYKLLHP Neucr2 PVYTVSPLPEWLARRQNFDFEEASNCVRVSEDGNWIMSSGTYKPQFHVHNTQELSLSFARHTKSENTTFIMLSQDYT-KSVHLQSDRSIEFHTPMGCHYEVRLPRFGRDLAYSTEVLIPSVGEVFRLDLERGQFLRP-VEFYDPR-SRNRVAVLEITALDG-LSLALGTGTGIVQVFDLRNPRPKDQGMGLPIKNILLTADKRIIKLWDEQSTSIEPDINHVS-GMLLTANEGKQMHSFFIPNLGLAPRWCHFLDNMVHEME--NT-YDNYKFLTIPELKQLSLA-HLVGLLRPYMHGYFVHSKLYDQARLIANPYV-WEEERAKRVKEKVEKARESRIKVNQKLVDKIDSRFGKLFEDEEFKVDETSREFRALNP Orpsp11 ----------------------------------------------------------------------------T-------------------------------------------------------------IEFWDPR-DKSCLTTLQISTVDG-LTFGVGTSTGQVLLYDLRNSKPKDHQYGYPIKNIIISADTKIVKIWNETTTNVEPDINDCT-GLMFLANEGSQIQSYYIPQLGIAPKWCTFLDNMTEEME--EM-YDDYKFVSKKELTSLGLD-HLIGVLRAYMHGYFVDLRLYQKAKSIANPFE-YEEYRKRKVQEKIEKERASRIKVNKAFASQLDSRFSSIFEDPEFAIDESTDVYHMLHP Pench1 PVYTISPLPEWLARRQDFEFEEASHCIRVSEDGEWVMSTGTYKPQIHTHYLPQLSLSWARHTSSLNTTFILLSSDYT-KSLHLQSDRSLEFHTPSGCHYTTRLPRYGRDIVYSTEALIPAVGEVYRLNLELGRYMRS-VELWDPR-AKGRAGVLEITALSG-MSLGTGSSNGLIHLYDLRSPVPKDQGYGFPIHTLLLSADKRIIKLWDIEDTSVEPDLNSVS-GMLLTANEGRQQHSFFIPQLGPAPKWCSFLDNLVEEMA--EV-WPGFTL--VPSEEVAKWDAKLIKKMVPYSKGYQVSNFVYNS---ITGLFPDTENPRAKKVAEIMNKERESRIKVNRRLAERMGGRFAALFEDQDFAVDETSREFQLLNP Phybl2 KVYTVS---------QDFEFPEASNRIKTTRDGKFAMATGVYKPQMRVFEFAEVSIKFERHMDAETVNFEILSDDWT-KVALLQNDRSVELHTQGGIHYRTRIPKFGRDLAYSCDLMLGASGEVYRLNLDQGRFMNP-VEFWDPR-SRSRVGLLEISALDG-LTMGLGTSTGHTLLYDLRASVPKDHQYGFPIKTIVIVSDCKIIKIWDRTNTSIEPDINDVS-GMIFTAQEGVQMGAYYIPELGPAPRWASFLDNITEEME--EV-YDEYKFVTRKELAALGLE-HLMGVLKAYMHGFFVDLRLYEKARLIANPFA-YDDFKERAVREKLEKERGSRISVNKNLAKKLDNRFSELFADPDFQVDEASKEYQLLHP Picst3 SVYQVSSLPDWIAKKQDFEFSEASNKIKVTPDGQFAMATGTYKPQIHVYDFANLSLKFDRHTDCENVDFLIMSDDWT-KSVHLQNDRSIEFQTKGGIHYRTRIPKFGRSLAYSCDLYVGASGELYRLNLDQGRFLNP-VEFWDPR-SRVRAAKLQVTAADG-LNFACGTSNGKALIYDLRTAVPKDQGYGFDIKKIILTTDKRIAKIWDRNDASMEPDINDIS-GMFFMANEGIPMHTYYIPNLGPAPKWCSFLDNVTEELE--EV-YSNYRFITRDDVVKLNLS-HLIGVLRSYMHGFFIDNELYDKVNLIANPNS-YRDRRDREIRKKIEKERESRIKVNKDLAAKLDDRFKELFENPDFAVDEESHDYKQLNP Plicr1 KVYTVNALPDWLTRKQGFEFPEASNRVKTTRDGHHAVATGTYKPQIRVWDLDQLSLKFERHSDAENVDFILLSDDWT-KSIHLQNDRSVELHTQGGFHYRTRIPRFGRALGYSCDAFIAGSGEIYRLNLEQGRFLNP-VQFWDPR-SRSSVGILSVTAIDG-LSYAVGTSTGHTLLYDIRAARPKDQGYGLPVKNVVLSADKKVIKIWDRNSTSITPDVNHVS-GLLLVANEGIQMTTFFIPQLGPAPRWASFLENITEEME--DV-YEDYKFVERSELRSLGLD-HLVGALKPYMHGYFLSLKLYDAARVIANPFA-YAEHREKLVRNKMEKLAEGRIKVNKALAEKIDPRFQKLFEDPQYAVDEATREFALLNP Polpo KIFNVSSLPEWLSEKQDFSFETSSRRVKITPDGQYLMATGIYPPQMKIFELSQLSSKVTRTMDAHVVQFEILSEDYS-KPVFLRDDRYIEFHAKFGTYFQTRIPKLGRDMTYSCDLYVGGAGEVYRLNLEDGRFVAP-IECWDPR-QREKVAAI-ISAGDG-LSLGLGTSTGSVILYDIRSPTPKHHQYQLPINSILLSADSKILKVFDKDTMVLEPPINDVT-GLLLMPGETQKIQSYYVPSLGPAPKWCSFLDNLTEELE--EV-YEDYKFITRDEVEKLNIS-HLIGFLKAYMHGFFIHIKLYNKFKSLVEVDG-YQEHRQNKIKEELNNKIVSRVMVNSKLANRLDTRFGKLWTDKAFEVDDESTEFRRHNP Pucgr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 KVYTVNSLPDWLTRKQGFEFPEASNRIKTTRDGHHAIATGTYKPRMKVWDLDQLTLKFERHTDAENVDFICLSDDWT-KSLHLQNDRTLELHTQGGFHYRTRIPRFGRALAYSCDAYVAASGEVYRLNLEQGRFMNP-VEFWDPR-SRARVGVLSVTALDG-LSYAIGTSTGHTLLYDIRSALPKDQGYGLPIKRLVLSADTKVIKIWDRNTTSITPDLNDVS-GLLLCANEGIQMNTFFIPQLGPAPRWCSFLENITEEME--DA-YEDYKFVERRELTSLGLD-HLIGALKPYMHGYFLSLKLYDTARVIANPFA-YEEHREKQIKEKMDKLADTRIKVNKALAERVDPRFTALFEDPEFQVDETTREFALMNP Rhior3 KVYTVSSIPDWLARQQDFEFPEASNRIKTTRDGKYVVATGTYKPQMRVFEYADMSMKFERHTDAETINFEILSDDWT-KQALLQNDRSVELHAQGGIHYRTRIPKFGRDLAYSCDLLVSASGDVYRLNLDQGRFLNS-VELWDPR-SKSRVGLLEVSALDG-LTMAVGTTTGHTLLYDLRSSMPKDHQYGFPIKNIVIVSDCKIVKVWDRHSTSIEPDINDVS-GLIFTANEGIQMGAYFVPQLGPAPKWASFLENLTEEME--EI-YDEYKFVTRKELKALGLE-HLMGVLKAYMHGFFVDLRLYEKARLISNPFA-YDDYRERVVKEKIEKERESRISVNKALAKQLDNRFADMFADPDFQVDEQSKEYQLLHP Rhoto1 KIYCVNA-AAWLEAKQDFDFPEASNKIKTTRDGKYLMATGTYKPRMKVFDLEELSMKMERVTDSENVDFCILSSDWT-KTLHLQSDRSLDLHTQSASHYSVRMPRQGRTLAYTCDALVGGTGQVWRLNLEVGRFMKP-VELWDPR-SRSRAGILAVTALDG-LNLAVGTSTGHVLLYDLRASKPKDQGYGLPVKKVVASADEKVVKIWGKETVAINPPVNDLT-GLVFLANETSPMTGYYVPQLGPAPKWARFLDNMTEEME--DV-YDDYKFVDRQELDDLNLT-HLIGTLKPYMHGYFVDLRLYTKARAIANPFQ-YAEHRDKLIRDKLAAEQESRIKVNKQLARRADARFADLFTNPDFEIDEASREFQLLNP Rozal11 RVYHVSSLPEWLVNKQDFKFPEASNRIKMTPNLQHVVATGVYKPQVKVFDTQDLSLKFERHFTSENVEFEVLSDDWT-KMVFLQNDRSIEFHAQGGCHYKTRIPAFGRDMKYTADLYVVGRSEAFRLNLDVGQFMNP-VEFWDPR-VRKSIYSLEVSSLDG-LSLAMGTSKGHALLFDLRQSTPKKHQYELPIINIMITSDKKVCKLWNKNTTSIEPDINDVT-GMIMMASESIEMQTFYVPSLGPAPSWASFLDNLTEELE--EV-YDDYKFVTLKDLKSLNLE-HLIGAIKAYMHGYFIDHRLYEKVKAIVNPFA-YDEY----VKQKKEEKVKSRIKINRTLAQKLDSRFADIFANEDFEIDEESNEYKLLHP Sacce1 SVYQVSSLPDWIAKKQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENVDFTILSDDWT-KSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNCDLYVGASGELYRLNLEKGRFLNP-VEFWDPR-SRSRVSKLQVTTTDG-LTFACGTSNGYSYIYDLRTSEPKDQGYGFDIKKIIVTCDKRIAKIWDRLDASMEPDINDIT-GMFFTANESIPMHTYYIPSLGPSPRWCSFLDSITEELE--EV-YSNYRFITRDDVKKLNLT-HLVGVLRAYMHGFFINTELYDKVSLIANPDA-YKDEREREIRRRIEKERESRIKVNKTLVDKLDDRFKEMFEDEEFQVDEDDYDFKQLNP Salro KVYNLTDVPMWLSERQDFDFPTACDAITISPDQQYVLACGTYKPRVRCFELSQMSMKFERHINCEAHKLLMLSEDYT-KFAMLLADRYIELHAAGGVHYRTRIPNYGRDLAYTADLLVAGLNNVYALNLAEGRFKEP-VKCFDPRTANTAIASLEITTLNG-LGLAVGTASGQVLVYDIRSTKPKDHNYGLPITYIMMTVDRKGVKFWNKETLAFEADINCAS-GLFFLGGEESKVMSYFIPALGPAPKWCGYLDTVADELD--EV-YDDYKFVTREDLGRLGLT-DLIGVLRAHMHGFFVDARLYNEAVEALNPFA-HEEYRQQRIKEQLEKGTASRLKVNRLLAKKMDPRFGAIFTDPEFEVDEAAEEYRAWRP Schco3 KVYTVNSLPDWLTRKQGFEFPEASNRVKTTRDGHHVMGTGTYKPQMRVWDLDQLSMKFERHTDAENVDFVILSDDWT-KSIHLQNDRTVELHTQGGFHYRTRIPRFGRSLAYSCDTYLTATGEVYRLNLELGRFMTP-VQFWDPR-SRSNVGILSVTALDG-LSYAVGTSTGHTLLYDIRSPRAKDQGYGLPVNNVILSADKKVIKVWDRDSASITPDLNDVS-GLLLTANEGIQMGSYFIPQLGPAPRWASFLENITEEME--DA-YEDYKFVERSELRTLGLD-HLVGALRPYMHGYFVSLQLYDAARLIANPYV-HAEQRERAIRDKMEKEAETRIKVNKALAERVDPRFAKVFEDPQFAIDENSTEFAMLNP Schpo1 RVYTVSRLPNWISKRQDFEYPEASNRIKCTRDGKYAMATGVYKPHIKVFDFAEMSLKFERHTDAENVQFEILSDDWT-KSVHLQTDRTVDFHSQGGIHYSTRIPKYGRDLKYNCDLYLAAAGEVYRLNLEQGRFLNP-VEFWDPR-DRSRVGILSVTALDG-LNVAIGLSDGATLLYDLRSSSPKDQGYSMPIKSLVLSADSKIIKIWEKDTSSIEPELNDVT-GLILTANEGSPMHAFYIPSLNPAPRWCSFLDNITEEME--EI-YDDYKFVTKKELLNLGLD-HLVGVIRAYMHGFFIDNNLYEKARLIANPFS-YEEHRQKIVKERLEKQRASKIKVNAGLASRLDERFKNVFTDKEFEVDEDTLEYKQLHP Sorma PVYTVSPLPEWLARRQNFDFEEASNCVRVSEDGNWIMSSGTYKPQFHVHNTQELSLSFARHTKSENTTFLMLSQDYT-KSVHLQSDRSIEFHTPMGCHYEVRLPRFGRDLAYSTEVLIPSVGEVFRLDLERGQFLRP-VEFYDPR-SRNRVAVLEVTALDG-LSIALGTSTGIVQVFDMRNPRPKDQGMGLPIKNILLTADKRIIKLWDEQTTSIEPEINHVS-GMLLTANEGKQMHSFFIPNLGLAPRWCHFLDNMVHEME--NT-YDNYKFLTIPELKQLSLA-HLVGLLRPYMHGYFVHSKLYDQARLIANPYV-WEEERAKRVKEKVEKARESRIKVNQKLVDKIDDRFGKLFEDEEFKVDEMSYEFRALNP Sphar KVYNVNSVPEWLTDRQDFDMPTAATRIKMSRDQQYLMASGVYKPKLKCFETAELGMKFERSLDCEIVQFQILSDDFR-KVVFLEADRYVEFHAHFGRYFKTRIPAHGRDMSYSCDLYLCGSSDLWRLNLESGRFMAP-VEVWDPR-TKELASGLEVTALDG-IKMAVGTSGGMVYMYDIRSDKPKDHQYGYPILDLVLSTDKRVIKIWDETDTAIESDINDTS-GLIMTANEGSDMQAFFIPDLGPAPKWCNFLDTISEELA--QI-YDDYKFVSKMDLETLGLS-DLIGLLQPYMHGFYMDMRLYQKAKAAVDPFS-YKDYRKEAIKKKISDKRANRIKVNTDYAKFLDDRFSSLWSNPEYSVDATSEEFKARHP Spipu1 KIYSVTAIPDWLARKQDFEFPEASLRIKPTRDGNYILATGVYQPQLRVYELAQKSMKLDRHQDCENVQFEILSDDWT-KTVMLQADRTIELHSQFGMHYKTRVPKFGRDLAYTCDLMVGGASEIWRLNLEQGRFLNA-LEFWDPR-ERRRIGALEISALDG-LTLAVGTATGQVLVYDLRSASPKDHQYGFPIKSLVVSADTKIIKIWNKDTTSVEPDINDVS-GLIMVANEGVQIQTFYIPQLGPAPKWCTYLDNLTEEME--EI-YDDYKFVTRKELSNLGLD-HLIGVLKAYMHGFFLDLRLYEKAKAIANPFE-YEEYKRRMVQERIEKQRASRIKINRSMAVKLDSRFADMFKDEDFQIDETSHEYKLHHP Sporo1 KIYCVNA-AAWLEQKQDFDFPEASNKLKTTRDGKHLVATGTYKPRMKVFDLEELSLKTERVTDAENVDFCILSSDWT-KTLHLQTDRSLELHTQSASHYRVRMPKHGRTLAYSCDAIVGGQGQVWRMNMEVGRFMKP-VELWDPR-SRTRAGILAVTALDG-LNLAVGTSTGHILLYDLRANRPKDQGYGLPVKKVVASADEKVVKIWGRETVAINPQINDMT-GLIFLANETSPMTGYYVPQLGPAPKWCRFLDNMTEEME--EL-YDDYKFIDRQELEDLNLT-HLIGTLKPYMHGYFIDLRLYTKAKAIANPFA-YAEHRDKLIRDKLAAEQESRIKVNKSLAK--DDRFGAIFENPDFEIDEESREFQLLNP Stehi1 KIYTVNSLPDWLTRKQHFEFPEASNKVKTTRDGKHVIATGTYKPQMRVWDLGQLSLKFERHSDAENVDFEILSDDWT-KTLHLQSDRTLELHTQGGLHYKTRIPRFGRALAYSCDALLGASGEVYRLNLEQGRFLNP-VEFWDPR-SRSSVGTLSVTALDG-LSYAVGTSSGHTLLYDVRSPRAKDQGYGLPVKKVVISADRKVVKIWDRGSTSLTPDLNDLS-GLLLTANEGIQMTTYYIPQLGPAPRWCSFLENLTEEME--EV-YEDYKFVSRAELSQLGLD-HLIGALKPYMHGHFISLKLYDAARVIANPYV-YEEEREKAIKAKMEKLAEGRIKVNRALAEKIDPRFSAVFQDPEYQVDERSREFALLNP Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr KVYNVSSLPEWLSEAQDLDFPSASNALKQSPDGKFLAVTGVYPPQFHVYELAMLSMKFERHVDAEIVDILHLSDAWH-KYVLLEVDRSLEFHTQGGRYYKTRIPKAGRSLAYNCDLYTGASGDVFRLNLDLGRFMKP-LEMFDTR-SQDKAGLVGVSSVDG-LSVAVGTTSGQVLLYDLRSAKPKDHHYDAPINSIIVSSDARTIRVWDYHDASIEPPINSSDSGLIMCTAEAPKVQVYYMPGLAPAPEWASFLDSLTDELE--EI-YDDYHFVTEKELKDLALS-HLIGFLKPYMHGFFMDTRLYKKVKSAVNPFE-YKTWREGEIQRKIDAGRSSRLKVNKAYARQIDPRFKPLFSDPRFSIDTDSDHYRRLHP Treme1 TVYTVNSLPSWITIKQDFAFPGSAIKIKTTEDGRHAIATGTYKPVIKVWDLDQLTVKFERVTDAENVDFVILSTDWT-KSLHLQRDRSLALHTQMGLHHSIRLPTYGRSLAYSADALIGCTGSVYRFNLEEGRYMTP-VEFWDPR-SRTALTRLSITALDG-LSLAVGTSTGHTLLYDLRNPNPKDQGYGEAIKSVVVSADSKVIKVWNRDDLSLHPSLAHLS-GLLFVACEAPQLCSYYIPEIGPAPRWAQFLDGVTEELEA-DV-YSDFKFVDKGELEILGLT-HLIGALKPYMHGYFLSLKLYATARLIANPQS-YAEHREKVIAERLAAKAESRIKVNKALAERLDARFKAIFEDPEYEVDEESREFALLNP Trire2 PVYTISPLPDWLARRQDFEFEEASQCIRISEDGEWVMSTGTYKPQLHVHNLPQLSLSFARHTTSLNETFVLLSTDYS-KSLHLQNDRKLEFHTPMGCHYEARIPRYGRDLVYSTEALVPAVGEVFRMNLELGRFMKS-VEFWDPR-SRSRVALLGVTALSG-LSLATGSSTGMIQLYDLRRPTPKDHGYGFAVKKLVLSADKRIIKIWDEATTSVEPDINDVT-GMLLTANEGKQQHAFFVPQLGPAPKWCSFLDNMVEEMA--ET-YDNYKFLTLPELKQLSLS-HLIGLLRPYMHGYFVASKLYEQAKLITNPYA-FEDERQKRVKERVEKERASRIKVNQKLVDKLDKRFTQLFEDEEFLVDENSGEFKALNP Umbra1 KIYTVSSIPDWLARQQDFEFPEASNKIKCTADGNYTVATGVYKPQMRVYEFAEMSMKFERHTDAENVNFEILSDDWT-KTVHLQTDRSIEFQAQGGIHYRTRIPKFGRDLAYSCDLLVGAAGEVYRLNLEQGRFLNP-VEFWDPR-SRSRVGLLEVSALDG-LSLAAGTNTGHTLLYDLRSNVPKDHQYGFPIKTLVIVSDCKIVKIWDRLNTSIEPDINDVS-GLLFTANEGIQMGAYYIPQLGPAPKWASFLDNLTEEME--EI-YDDYKFVSRKELNALGLE-HLIGTLKAYMHGFFVDLRLYEKAKLIANPFA-YDDYRERIVRDKIEKERSSRIAVNKELAKKLDDRFKDMFADADFQVDQESNEYKLLHP Ustma22 RVYTVSSLPDLLRRSQDFEFPEASNRLTATRDGQSIVATGTYKPQIRVWDCEQLSLKFERHTDAENVDFLMLSDDWT-KSLHLQTDRTVQLQAQGGAHARVRIPKFGRALGYSADAVVAAAGEVYRLNLDQGRFLAP-VEMWDPR-MRKRAGLLSVTALDG-LNLAVGTNTGHVLLYDLRMDRPKDQGFGLPIKKVVLSADAKVIKIWDKDSVSVTPDINDVT-GLLMAAVEGTQMAAWYVPALGPAPRWCSYIDTLTDEMDGVDV-YEDFKFVDRAELDRLGMS-HLIGLLRPYMHGYFISLALYERARLLNNPTA-YADARERAIKAKLEKQAESRIRVNKELAEKVDSRFSQLFQDPEFQIDTGSREFAMLNP Walse1 KVYCVNSLPQWISKRQEFGFPEASNKVRTTPDGEFALATGTYKPQVRCYDLRELALKWERHTSSENVDFQILSNDWT-KSVHLQNDRTVSVHSQSQLHYSIRVPKFGRSLAYSCDTLIGGTGQVYRLNLEQGRFLNPGVKFWDPR-SRNQIGSLGVTALNG-LSLAVGTSTGHTLLYDLRASKPKDQGYGLPIKNLVASADSKVIKIWDKESVNLTPDINDMT-GLIMLANEAPDMSSYYVPQLGPAPKWCRFLDNITEELEG-DA-WSDYKFVDKNELENLNLG-HLVGALKPYMHGFFMSSELYSTAKMVSNPFA-YAEHREKQIQDKLEKQAESRIKINKNLADKVDDRFKDMFENPDFEIDEESKEYALRNP Zygro1 SVYQVSSLPDWIAKRQDFEFSEASNRIKVTKDGQSAMATGTYKPQIHLYDFANLSLKFERHTDAENVDFLFLSDDWT-KSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLAYNCDLYVGSSSELYRLNLEQGRFLNP-VEFWDPR-SRSRICNLEVTTTDG-LNFACGTSNGYTYLYDLRSSEPKDQGYGFPLKKIIMTSDKRIAKIWDRVTASMEPDINDVT-GMFFTANEGIPMHTYYIPHLGPSPRWCSFLDSITEELE--EV-YSNYRFITRDDMKKLNLS-HLIGVLRAYMHGYFINNELYDKVALLANPNA-YRDEREREIRRRIEKERESRIKVNKELVDKLDDRFKEMFADDDFQLDEDDYDYKQLNP [Cluster2056.fasta_al_trimmed; alignment length = 129] Allma1 KSTTDRVAHQSRPAKA-RLSATERRRMQLTAIPSYATYAPLHALWRAYMDDLVAVAKADWHGAKVVVTRAKNPTLVGVSGIVVQESARTLKVVAKPGAQWTVVLGAYTVHGDQVAYRSADRAARKMKSR Ashgo11 PIDEKRL--KKRKANLRNINKNSKVALRAKKIASYEQYEPMTDLWCKYMQELLKLSMADYNGCLLNVSKSRNTNMVGVGGIVLWDAQKSFVVLPKKGSVFTFEV--YSIIGDRFNYRSADRAGRKFKSR Aspfu1 QLFTERVKMHRVRKKEKPLSAREKRISGLYDLPKYSIFQELHKLWVGYMQEILKLVTADFHGAEVEVVRSRCPGRVGVKGIVARDTKFTFMI--KKQTIFRFTVPLFELHGSQFENRPVDRANKKFKWR Aurde31 AYYENRVKRLARREKDRKLGAKLPEVKGLWELDQWSVFEPIHRLWLGYMAELLKLVKADFHGCIVTVRKAKNPFLVGRSGIVIHETENTFKVLPKRNSIFVFSIPLFELYGNQFCYRSADRANRKFKHK Batde5 --------------------------MGMLSLPKFEVFVPLHTLWMGYICQVIKLIKADFHGAFLTVVKSKCPSNIGISGIVIKDTENMFHLIPKQGNVFTFGVG-ITLYGNQFRTRPADRASKKFKAK Botbo1 QVYASGVKKKVRRAKHGVLGRTAAKRMGLWNLERYDTFLPIHHLWLGYMAELLKLVKADFHGSILTVRRSKNPSLVGCCGIVIHETENTFKLIPKQNSVFAFSIPLFELYGNQFRFRATDRANRKFKAK Botci1 -------------------------------------------MWLGYISEVLKLCSADYHGAELEVVRSRCVSRVGVKGIVIKDSKGVFEVLPKENTIFKFTVPIFELHGEQFMHRAADRANKKFKPH Caeel --------HFKRKSKKGRLTEDDKKAFK------FADIVPMNTDWQKYFRERLTILKSDYHGALLTIWLAENPTQIGISGIVVLETRHTFQMIPKKGSVFRFILG-FSLFGDGMRTRPAWR-GKKPRIK Canalb1 ELLQDRYS----KPRS------TRQVLRIKKIQSFDDFFQMNKLWQKYAQDLIRLTAADFNGCLLTVLQSRNTNVIGTRGIVVWDAQHSFILIPKKHTMFGFDIIDFTIVGSRFEIRSVERSGKKFKNH Cangl EIDEGRL--KKIIEKRKKINKRSKQSLKAKQIAHYEKFRPLSELWISYIQELLKLSMADYNGAALRVTKSKNHNTVGIEGIVVWDAQKNFIMIPKKGTLFDFEI--YSILGDRFKYRSVDRAGRKFKTR Capow KTIAGKLQKARAKL--RLLTSAERRGLNVFNIDRYDLYVPLHTMWVQYLTEYLRLLKADFHGCLLKVDRSKVPSCVGATGIVLQETSNTFKILPKAGSVFTFTVG-FELFGSQLCYRPAERIGRKFKAK Catan2 QVYQEK----------KYLSSRERRSLGLMTLPTFAAMKPLQHLWNQYMDDLKKLIKADFHGAHMTVTQATCPTLIGISGIVVQETAKTFNLICKQGTVFSVVIG-YHLYGHQLQYRSSERAARKFKGK Cioin KKLEKQLVGKVKKKKQ-------KADLKALTQNSYE---PLRKMWSEYIREVLVFLKADLHGAVISVVLSNCKHLEKTKGTIITESKNMFQIIPKKNSVFEI---IVTIFGDQFCIKPSQRLTKKFKNY CocheC53 SHYRERAVALNERKEARPLSAAKKRALGLNEISKYAIYEGLHNLWIGYMREVLILATADMHGALVTVVRSRCVSRVGLEGIVVRDTRFTFDLVPKEHTIFRFQVPLFDINAEQFQTRAADRANKKFRIH Coere1 --------KPGRIGESKRITAKEKRELKLYEIPEYELFMPLNKLWSKYIESLLKLIKADLHGAKMSVVRARCPNFIGISGIMAQETKNAFKFVPKAHCVFAVKLP-CLIYGDQFMFRASERASRKFKPK Conco1 SIVSEKIQKLKRSQKRNPITNRLKREFKCFQLDPYDALLSLNYLWIQYIRELKHLLKADLHGSILTVTKSKNHTLVNQSGIVLQEFKNIFKIISKSDSVFQIDFD-YELFGPQIVGRPADRSVKKFKEK Conpu1 TLYAQRVQRRARKVAQGVMSSREAKGKGLWKLEKFELFVPLHHLWMGYMSELLKLVKADMHGSILKVSQSKNPSLVGLEGVVIHETENAFKVIPKQNTIFVLSVPLFQLYGNQFCFRSAERAGKKFKAK Copci SLYNARVKKGEVRRREGMGGKGRREERGLWK--AFASLVPLHHLWLGYMSELLKLLKADFHGALLKVKNAKNPCLVGLEGIVVHETENAFKVIPKQNSIFTFSVPLFELYGNQFRFRSTDRAGRKFKHK Croqu1 KNLDQKVFNEID-LES-----RRKKYLELEKIIKYENFIPLHSLWIGYMSELLKLLKADYHGSVLSVCRSKNPSLIDLKGIVVQETQETFKLIPKKHTVFKLELKFFEIYGNQFCFKSTDRVGKKFKTK CryneH991 SVYSSRLSNRGNECEKRNVKTRERLGLEMRKVKKYNALIPLNHLHINYLCQLLKISKADFTGIYLTVLAAKNDDLKDQRGIVIEETAETFRLIPKSGSLFRLSFPAMDLLGSAFAYRSADRAGRKFRPA Crypa2 RIYTEKIQRRKERERKKPLSAKQRKKLGLYEVPRYATFVPLHDLWLGYVREILKLSAADFHGAEVEVVRSGCVGRVGIKGIVIRDTRFVFEVVPKEGTMFRVEVPPFEILGDQFAIRAADRANRKFKPH Debha1 ELLSTRYS---NKTKA------TRIELKIKKIQAYEEFIPISNLWQDYMQNLLKLSSADYHGCLLTVLKSTNRLLVGVRGIVVWDTQHSFILIPKKGCLFGFDVILFTVIGSRFEFRSVDRSGKKFKNH Dekbr2 KLLEDRYSKRRKKKKE--YGKRTKNTFKVKGLKKFEDFQEINRLWNNYAKELIKLSTCEFIGAFVEVTHSGCINNIGQKGIIIWESQHNIIIINKEGTRFKFRVNVFEIIGDRLMVRSIDRANKKFKNH Dicdi DIVDENIDERK--ERLKKLGSKKKRELSFFSISSYDQYLPLHQLWTQYIQDVMKILKADLHGAIVIVTKSKCPTFVGQKGIIVQETENTFKIIPKEQCQFYLECC-VTIFGKHFCFRACDRANKKFKPR Dmel MLEGTKIK--------STLSRREYAALGLNTLPTYEEALPLHHLWKGYVREHLKLVKLDLHGAKMKVLQSKCSTLENLAGICVMDTKNVLKLIPKSECVFGMKVG-FTIFGQHLNIRPAERSVKKIKNF Enthi EAKEERID-----------TKVMRRPIGIQQLKQYFLFKTLNQLWIQYIDKIMSLLNAEIQGGEISIIQSKNPSLVGKRGICVYESKNVIVLIPKEVVNMKLHYK-IILYGRNWTIRPCDRIETNFKEN Falba TAFEQRALEVEASGAEAIVSAKRARAEGWFSVSPFARIVALHSLWQDYMRAVLKILKADWQGSIVSVVQSKSPTLVGKSGIVVRETAKTFELVPKRGAVFSMTVPGVTIYGDQVCCRAAERSTRKFKGQ Fomme1 ALYENRVKTKSRRAKEGLISKKEARFKALWRFEKYELFVPLHHLWLGYMSELLKLVKADFHGSILRVKQAKNPCLVGLSGIVVHETENAFKVIPKQGSIFTFRIPLFELYGNQFRFRAAERAGRKFKPK Fusgr1 RIYSEKIQRRKARQDKKPLSSRERRNLGLHDIPRYHIYEPLSQLWLGYARELLKLASAEFHGAPIEIVRSHCPSRVGIQGIVVRDRKFVFEIVPKEGTIFRVEVPLCEVFGDQLMLRAPDRANKKFKAH Galma1 -MYTARVKKRVVRKKEGVIGKREAKERGVWKFDEFDLFLPLHNLWMGYMSELLKLLKADYHGSIMTVSQSKNPCLVGVSGIVIHETENAFKVLPKQNSIFTFAVPLFELYGNQFRFRAAERAGRKFKHK Ganpr1 AAFQSRLERKAIKKSR--MTAKERRTWGAWEVPKFELFVPLWQLWGQYTRELFKLVKADYHGAFLTVVKSRCPGYVGMAGIVVRETENTFILVPKAHSVFAFSVPVFHLYGDHIQVRASERSSKKFRQA Gloin1 --------KKKRTI--KTMSAKEKRQTRIYEIPKYELFVPLHELWLQYIEELYKLLKADFHGAILTVSKSKCASYIGVTGIAIQETENMFKLIPKGHSIFTFRLR-FTLYGDQFRYRSAIRATKKFKNK Hisca1 NIFTERVKLHRLRKKEKPLSAREKRITGIYNLPKYDIFKGLHQMWIEYMHDVLLLASADFHGAELEVVRSRCVSRVGLKGIVVRDSKFAFVVIPKEHTIFRFQVPLFELHGSQFENRPVDRANKKFKWK Klula1 PINENRL---RKKSKAKAVNKNSRVLLKCKKLAKFETFSSMEDIWCPYMKELLKLSMADYNGCKLKVSKSKNKSLTGKNGIVIWDAQKTFIIIPKKGTTFDFEI--YTILGDRFKYRSVDRAGRKFKSR Lacbi2 -MYASRVRKRLRRKKQGIIGKREAKEKGVWKFDEFALFVPMHNLWMGYMSELLKLLKADFHGSIMTVHKAKNPCLVGISGIVIHETENAFKVIPKQNSIFTFAVPLFELYGNQFRFRSADRAGRKFKHK Lenti61 QAYASRVQKRAQRAAEGVVSKKESRKRGLWKLQKFELFLPLHSLWLGYMSELLKLIKADFHGSIVTVRQSKNPCLVGLSGIVIHETENAFKVLPKQNSIFVFAVPLFELYGNHFCYRAAERAGRKFKHK Malgl1 --YDARIHKQYRKALRKPKTKNSKRKNQRIHHDELDQVQPLVHLWTAYIRDALSLLKMDWTGAHISVVRSSQPNLVHTSGIVVKETHETFAIIPKCNTVFQLALPLVDLHGNQVRYTLPVRVTRKHKAR Mellp23 ------------------------------------------------MSELLKLLKSDYHGAILT--------------------------VPKRHTVFQIELEILEIFGNQFAFRAADRVGKKFKTK Mnele NLVNNHIK--------QPLSHKERRQLGLDTLKQFKELALIHKLWCEYVTQIGDLARADLHGCFLTVTKTTCPPLLRKSGIVAMESLNTFTILPKRGSVFSFVVN-VNIFGNNFIFRPGERILKKVLKQ Monbr QLVESKVH--------TKANSNRRKEVGAITIPA-------------------RLARADFHGARITVVRHKSPGLVGVTGIVLQETENTLRILPKSAAIFGFELG-VNVYGNNLRFKPSDRAVRKFKLR Morel2 KVFSQKVKRRKRA---KVLTAKEKRQLNVYDIPLYELFEPLHELWKGYVEELFKLLKADFHGAIITVARSKCPTFIGVSGIVAQETENVFKIVPKVNSVFTIHIR-FTLHGNQFRYRASQRSSKKFKSR Mucci2 KVLNEM--KELAKK--GKLTAKEKRRLKVYDIPKYKLFEPLSQLWQGYMSRLLKLIKADFHGATMTVVQTTNPSYIGVTGIVIQETMSMFKIIPKNSSNFDIYIQEYRLYGPQFVARPAERASKKFKPK Mydma DKLKLRLK--------LKVSRKLNKQFGLHEVPKYIDFLPLHSLWLQYIKSNFKLLRIDFHGAQIKVRNSKCKSYIGLNGIVVKETKNIFVIIPKSMSIFELKLN-VKIAGDAICVLPSIRASKKFKST Neucr2 RILTEKIQRRREREKKKPLSANERRKLGLYDVPRYALFEPLHQLWLGYIREILKLTSADFHGAEVEVVRSGCVSRVGLKGIVIKDSRFTFEVVPKEGTVFRIEVPLFEVHGEQFQFRSADRANKKFRSH Orpsp11 NVYDTKVEQKEEKTKENLMSRRERKKSG---------------MW-----------------------------------------------IPMEAR------------------------------- Pench1 QQFTERIKLHRLRKKERPLSAREKRKSGLYDLPKYDIFKGLHELWVGYMQEILKLVSADYHGAEVEVVRSRCAGRVGAKGIVVRDTKFTFVIIPKEHTVFRFTVPVFELHGNQFENRSVDRANKKFKWR Phybl2 --------KKMRK---RRLNARERRAFKVYDIPAYDIFVQLNKLWQGYMAEVYKLLKADFHGAIFKVIKSKNPSYVGIEGIVVQETLSVFKIIPKISSVFTMEMECFTLYGPQLQFRAADRAVKKFKPK Picst3 QLLDTRYS----KQKS------ARLQLRVHKIQKYEDFNNLSHLWQSYMGDLLKLLSADYTGCLLTVTQSRNTNMVGTRGIVVVDAQFSFILVPKKGTLFSFDVIVFTLIGSRFEFRAVDRAGKKFKSH Plicr1 GLYASRIQKRKRDADARVMTARTAQARGMWKLEKFELFLPLHHLWLGYMSELLKLVKADFHGSIMTVRQSKNPCLVGISGIVVHETENAFRVIPKPHSIFSFAVPLFELHGNQFCFRAGDRAGRKFKHK Polpo QIINSNYMQKKVEEKESQLNSRKKRDTKFFDIAPYDHYLPLNELWRQYINDVLKLIKADLHGAVLQVSRSVCPSLIGQIGIVIQETENTFKI-----ETITIRVC-GCGNGLYHSFDT----------- Pucgr2 KNYQSKVNNQFSGMKS---TNRQVQFLELEKLIEYQDFVPLHQLWLGYMAELLKLLKADYHGAHLSVHKAKNPSLVDLQGIVIQESEQTFKLIPKAHTIFELSLPLFKIFGNQFIFRPSERINKKFKSK Punst1 -QYANRVQRRNERRKAGVMGKREAREKGIWKLDPYALFLPLHHMWMAYMSELLKLVKADFHGSIMTVRQSRNSALIGLSGIVVHETENTFKILPKQHSIFAFAVPLFELHGNQFCYRASERAGRKFKHK Rhior3 KLVEGL--KKAKKE--RKLTAKDKRQLKVYDIPKYKLFEPLSELWQGYMSSLLKLIKADFHGAPFTVIQSTNPSYVGVSGIVIQETLSMFKIIPKNTSIFNIYVRQFTIYGQQFVSRPSDRAAKKFKPK Rhoto1 EVADERIAAVRESEKEGLAGRRKRAAMG--KAAVYESVLPVYHLWLGYMAELLKLIKAEFVGCLLSVKRAKNPSLVGIKGIVLQETQGTFKVLPKQGTVLTLVLPFFDLYGDAFAYRPADRVGKKWKAG Rozal11 SSIQEKLKAKISKKKV--LTAVEKRKLKAFEIPKYECFTKLNELWNGYITEVLALIKSDLHGAKIKVQRSKNKSVINKSGIIVKETANTFQIIPKMNSVFLLTTPI-LLFGNSFCIKSAERITKKFKQK Sacce1 PFNENRF--QRQQRKSQRINKNSKIALRCLKLAYYVDFVPMKELWINYIKELLKLSMADYNGALLRVTKSKNKTLIGLQGIVIWDSQKFFIMIPKKGTVFQFEI--YSILGDRFKYRSVDRAGRKFKSR Salro AVVRSKLEAETTPQHL-------KPKQGFFELEPYANFEPLHALWKQYMQQILALVKADFHGCCITVVKSRRPGLIGQAGIVIQETENTFRILPKCDSIFSFELG-FTIFGNHFRLKPVDRAARKFKAK Schco3 AIYNDRVYREQKHRELNVMSRKETREYGLWELTKFELFLPLHHLWMGYMSELMKLVKADLHGSILTVKQSKNADLVGLGGIVILETENAFRVIPKENTIFSLALPLFELYGNQFRFRSADRATRKFKNK Schpo1 NVINEKIAKQGDRKESKKLSSKEKKKLQLNVVPKYSQFKHLHSMWCSYILEVIKLAKAEYQGAYMQVLRSKSTTRVGLEGICIHESKHMLSLVPKQDSVMKVIVDVFELYTQHLLLRAGDRSNKRFKSK Sorma RILTEKIQRRREREKKKPYPPTERRRLGLYDVPRHALFEPLHQLWLGYIREILKLTSADFHGAEVEVVRSGCVSRVGLKGIVIKDSRFTFEVVPKEGTVFRIEVPLFEVHGEQFQFRSADRANKKFRSH Sphar QNYRTKVEKRIHKHHQ------------FFALPDYEKAMPGHAMWLEYVSHLWLLVSVDMHGCLITVSNARNASLVGVSGIVLQDSVRTFTILPKDGATFTTNAH-IVWHGNGLIAERLTRAKAKIKKK Spipu1 LNYETKVKQQRRSKKDKRMSAKERKETGVWDVPVYALYVPLHNLWQGYINDLFRMMKADYHGALLTVAKSKCPTYIGISGIVIKETENMFYIIPKRNNVFTFQVN-FTLYGNQFRTRAGERAAKKFKEK Sporo1 QVAEERLSAMIEREKDGLMGKRKRAAMG--KVAVYAAVLPVHHLWLGYMAELLKLVKAEFVGCILSVKRAKNPSLVGMTGIVLQETQGTFKLVPKQNTIFTITLPLVDIYGDSFAYRSAERVGRKWKAG Stehi1 KYYEERIKKKRRQDKEGVLGRDDAIERGTWKLSKYDLFIPLHQLWLGYMSELLKLIKADYHGCIITVVRARNPCLVSLSGIVVHETENAFRVVPKQNSVFSFAVPLFELYGNQFQFRASERAGRKFKHK Tapde11 --------------------------------------------------------------------------------------------------------------------------------- Thetr RVSSDATTKEKRRQVAVRASRKAVRKVR---VPRYEALLPLHHMWKKYAATCLHIGKLELAGALLSVVSSKSPSLVGVQGLVMAESAQMFTLVPKASCVFGLIWD-ITLHGPNICFRASERAARKLKAR Treme1 ISYSSRLAEFGDGSKLRKVLDGEKTEMGIRRMKKYEFLLPLHYMHTHYLISLFKLVKADFTGAILLILSSRNPSLVGIKGIVIEETYGTFLLVPKKGSMFRFEFPAIDILGDNFCHRSVDRAGRKFRPT Trire2 RIYSDKIQRHRARQQEKPLSARERRQLGLYDIPKYEIYEGLNKLWMGYAMEILKLASAEFHGAEAEVVRSRCPGRVGLKGIIVRDRKFVVELIPKEGTVFRVEVSAFEVYGDQMMLRSADRANRKFKSH Umbra1 QTINTKIQRPKKKP--KRITSREKRQLGLYTIPKYDLFLPLHELWKGYMEELLKLIKADYQGAILSVVKSKSPSYIGTSGIVVQETESMLNIIPKAASIFNMTVK-FAIYGNQIRFRAAERATRKFKVK Ustma22 QYYRERLQRKLIKRKRKPLSRSQRKRMGLEQVDSYELVKPLHDMWRSYIQQLLSLIKADLCGAEIEVVRAANPSLVSQHGLVVKETEHTIIIIPKKNAVFAIKVPLFELHGNHMMHTLPSRATRKYKAR Walse1 KIYSSKLE--------KPTKSKLRRQTIRHSIKRYDVAKKLNRMWNEYINDLIKMLKADLCGSAIKVIKSNNPTLINMEGICILETEQSFLILPKNGGVFELKSDVLNLYADNFKYRNVDRLNKKFKHK Zygro1 PISDNRL--RRNKSKLRKITKNARVALKAKRIARFDKFKPMEQLWIGYIKEMLKLSMADYNGSFLKIVKSVNKNMIGIEGIVIWDSQKNFIMIPKKGTIFALEI--FSILGDRFKYRSSDRAGRKFKAR [Cluster2057.fasta_al_trimmed; alignment length = 123] Allma1 KAPPEGFDDIEPQLLEFEQKMREEGLRKAEASWPIFRLHHQRSRYVYELYYKRRAISKELYDYLVKQGYGDANLIAKWKKPGFENLCCLRCIQPRDTNFGT-ACICRVPKKNMITCHHC-GCR Ashgo11 SPPPAGFDKVEPTLAAFAEQLRDRGPRASAAAWPVFRVTHERSRYVYTMYHRRRAISRALYDWLLRHRYADRYLIAKWRKQGYEKLCCLRCIQPGESQY-GHTCICRVPRAALEQCTRC-GCR Aspfu1 KPPPAGFDDIEDTLLEFSNKMKDDGKKKHEMLWPIFQISHQRSRYIYDLYYEKEAISRQLYEWLLKNNYADANLIAKWKKQGYEKLCCLRCIQTKETNF-NATCICRVPKAQLIQCVSC-GCR Aurde31 KAPPEGYDEIEAILEDYAKKMRDEGKRRAESLWPIMRISHARSRYVYELYYKREAISKELYDWLLKEGYGDANLIAKWKKAGYEKLCCVRCIQTKDMNNQGSTCICRVPKAQVVECQHC-GCR Batde5 KPPPEGWELIEPTLTELAQKMRQEAKRKVETAWPIMRLHHQRTRYIYDIYYRRKAITRDLYDYCIKQGHADAALIAKWKKTGYEKLCCLRCIQPKDTNF-GTTCICRVPKQQLIECVHC-GCR Botbo1 KQPPEGYEEIEGILEDYAKKMRDEGKRKTESLWPIMRISHTRSRYIYDLYYEQEAISKQLYDWLLKEGYADGNLIAKWKKPGYEKLCCLRCIQARDMNFQGSTCICRVPKGQLVECTHC-GCR Botci1 KAPPNGYSDIEDSLLVYSNKMKDSTGPRHQATWEITQINHQRSRYVWDMYCEEK-ISKALYDWCVKNGQCDATLVAKWKKEGYEKLCCLKCVQTKETNF-NSTCICRVPKADLIQCLVR-GCT Caeel KSPPEGWDLIEPTLEQFEAKMREEGKRKTEINWPIFRIHHQRSRYVYDMYYKKAEISRELYEFCLTAKFADAALIAKWKKQGYENLCCVKCVNTRDSNF-GTACICRVPKSKLIECVHC-GCH Canalb1 GPPPEGYSKIEPTLTKYRNKLKSPTKSKQSSLWIIYQLNYKITRYVYDTYVAKR-ISKELYDWLLLQNDINKDLIAKWKKPGYEKLCCINCI-STNTNG-GGTCVCRVPKAKLIECITC-GCR Cangl ----KGYERVEPVLAEFERRLKEKGQGK-EDLWRIVQIHSERSRYVYTMYYKRRAISRELYEWLLKKKVADRRLIAKWRKRGYEKLCCLQCVQQSETNH-GSTCICRVPRLQLKECVNC-GCH Capow KPPPEGWDDIEPVLNDFAQKMREEGKRRVESLWPIFRIHHQRTRYIYDMYYKRKVISKELYEFLLKDNYADANLIAKWKKQGYENLCCLRCVQTKDTNF-QANCICRVPRASLVECVHC-GCT Catan2 --------------------------------------------------------------------------------------------------------------------------- Cioin KPPPDGWELIEPTLDELDQKMREDGKRKVETLWPIFKIHHQKTRYIYDLFYKRKAISRELYDFCLKESIADKNLIAKWKKQGYENLCCLRCIQARDTNF-GTNCICRVPKSKLVECVHC-GCR CocheC53 KAPPEGFDDIEDTLLEFQTKMKDEGKKKYEMTWPIFQITHQRSRYIYDLYYTKEAISKQLYDYLLKNGYADPMLIAKWKKQGYEKLCCTRCIQTKETNF-RSTCICRVPRDQLIECVNC-GCR Coere1 MQPPEGWSDLEPTLEEFKQKMRDAGKRKVESTWAVMRVHHQRSRYIYDLFFKRKAISREIYDYCLKNGYADGNLIAKWKKQGFEKLCCLQCIQPRDTNY-GTTCICRVPKDKLVECVHC-GCR Conco1 KKPPAGFEEIEPNLNEFAKKLRDEGKRKVEAVWPVFQITHARSRYIYDLYYKRKAISKEVYDYCLKQKYADGNLIAKWKKAGYEKLCCLRCIQPKDTNF-GNACICRVPKKKLIECILC-GCK Conpu1 KQPPEGYEDIESVLDDYAKKMRDEGKRKAESLWPIMRISHTRSRYIYELYYKREAISRELYDWLLKEGYADANLIAKWKKTGYEKLCCLRCIQTKDMNYQGSTCICRVPKAQVVQCVHC-GCR Copci KRPPEGYEDIESILDDYARKMRDEGKRKAESLWPIMRISHARSRYIYELYYKREAISRELYDWLLKEGYADANLIAKWKKTGYEKLCCLRCIQTRDMNYQGSTCICRVPKAQVVECVHC-GCR Croqu1 KPPPEGFEEIEPILDEYARKMRDEGKRKNESVWPIMRINHIRSRYIYDLYYKREAISTELYEWLLEESYADANLIAKWKRTGFEGLCCARCVQSRDMNYAGSVCICRVPKAQLVECVHC-GCR CryneH991 KPPPEGFDDIQDVLEDYEKKMRDEGKRKVEAVWPIMRLSHARSRYIYDLYYKRELISRELYDWLLKQGYADANLIAKWKKNGYEKLCCVRCIQTRDMNFQGSTCICRVPKAQLVECPHC-GCR Crypa2 --------------------MKDDNVPKHQAQWPIFQISHQRSRYIYELYYEKEAISKQLYDWLLKNNYADAMLIAKWKKQGYEKLCCLRCVQTKETNF-SSTCICRVPRAQLIQCVSC-GCR Debha1 KQPPEGYSKIEPTLSKLLVKSREKTENKNQSLWPIIQINHQINRYIYSLYYERELISQELYNWLLQQKYANKNLIAKWKKQGYEKLCCLNCIMTNEKNH-GTTCICRVPKTTL-ECITC-GCR Dekbr2 KEPPEGFSKIEHALNTFSEKMKEVNRPKYESTWKITMLNHQRSRYIFDLYYKRKSISRKLYDWLIANKFADKELIAKWKKNGYEKLCCLQCIQVGNTNQ-QTTCICRVPKASMIRCKNC-GCR Dicdi KKYPRGWDIISPTLDEFDIKMREEGKRKNEVNWPIFRIHHQRSRYVYEKFYKNKEISRELYEFCLTEGYADKNLIAKWKKPGYERLCCLKCIQ--DLSH---ICICRVPKKDLLECSSC-GCK Dmel KPPPDGWELIEPTLEELEQKMREEGKRITESLWPIFKIHHQKTRYIYDLFYRRKAISRELYDYCLKEKIADGNLIAKWKKSGYENLCCLRCIQTRDTNF-GTNCICRVPKCKLVECVHC-GCR Enthi --------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------- Fomme1 KRPPEGFEDIEGVLDDYAKKMRDEGKRKTESLWPIFQLNHARTRHIYELFYKRQAISRELYDWLLKQGYADANLIAKWKKTGYEKLCCVRCIQTRGMNYEGSTCICRVPKAQVVQCTHC-GCR Fusgr1 KPPPDGFEDIENDLLIFANKMKDPSGPRHQAQWEIFQISHQRSRYVYELYYEKEAISKKLYDWLLKNGYADAMLIAKWKKQGYEKLCCLRCIQTKETNF-NSTCICRVPRAEMIECVSC-GCR Galma1 KAPPEGFEEIEEILEDYAKKMRDEGKRKAESLWPIMRISHARSRYIYELYYKREAISRELYDWLLKEGYADANLLAKWKKTGYEKLCCLRCIQTRDMNYQGSTCICRVPKAQVVECVHC-GCR Ganpr1 KPPPDGWEEIEPTLTELNQKLREEGKRKAESLWPIFRVHHQRSRYIYELYYKRHVISKELYDYCVNERYADATLIAKWRKPGFERLCCLQCIQTRDTNF-GTTCVCRVPKDKLVECRHC-GCR Gloin1 KKPPEGFEDIEETLQEFARKMKDEGKRRVESLWPIFRLHHQRSRYIYDLYYKREAISKDVYDYCLKHGYADGNLIAKWKKPGFERLCCLRCIQPKDTNF-GTTCICRVPKSKLVECVLC-GCR Hisca1 KPPPDGFDDIEDTLLEFSNKMKDEGKKRHEVLWPIFQISHARSRYIYDLYYEKEAISKQLYDWLLKNNYGDALLIAKWKKQGYEK------VRT----------------------------- Klula1 KKAPEGFDKISPTLNEFAIQLKELSTKNTESTWQVFQIHHERSRYVYNLFYKRKAISRELYEWLLREKYADKQLIAKWKKKGYEKLCCLQCIQSNETTN-GKTCICRVPRATLKQCIHC-GCS Lacbi2 ----------TKILDDYAKKMRDEGKRKAESLWPIMRISHARSRYIYELYYKREAISKELYDWLLKQEYADPALIAKWKKTGYEKLCCIRCIQSRDMNYQGSTCICRVPKAQVVECVHC-GCR Lenti61 KKPPEGFEDIESILDDYAKKMRDEGKRKTESLWPIMRISHTRSRYIYELYYKREAISKELYDWLLKEGYADANLIAKWKKPGYEKLCCIRCIQTRDMNYQGSTCICRVPKAQLVECVHC-GCR Malgl1 RPPPDGFEDIEPILEEYETKMRDDGKRKAEGVWGIMRITHIRSRYIYDLYYKREAISRELYDWLLEQGYADAALIAKWKRTGYEKLCCVRCIQARV----VVAAVHLIKQFTL-------FCR Mellp23 KPPPEGFEEIEPILDEYARKMRDEGKRKNESIWPIMRINHIRSRYIYDLYYKREAISTELYEWLLEESYADANLIAKWKRSGFEGLCCARCVQSRDMNYAGSVCICRVPKAQLVECIHC-GCR Mnele KPPPEGWELIEPTIEELDAKMREEGKRKVEALWPIFKIHHQKSRYLYDLYYKRKAISKELYDYCIKEKIADANLIAKWKKDGYERLCCLRCIQVRDTNF-GTNCICRVPRSKLVECVHC-GCR Monbr KQPPEGWELIEPTIEELDMKLREDGKRRCESLWPIYRIHHQKSRYIYDLYYKRKAISQELYDYCLKENIADRNLIAKWKKNGYENLCCLACVQTRDTQH-GTTCICRVPRSQLVECVTC-GCR Morel2 KRAPEGFDDIEPTLREFQTKMKDEGKRKIEALWPIFRLHHQRSRYVYELYYKREAISKELYEYLLKQGYADANLIAKWKKAGYEKVCCLRCIQPKDTNF-GTTCVCRVPRDKLIECIHC-GCR Mucci2 KRAPEGFDEIEPTLEEFARKMKEEGKRIVESTWPVFRIHHQRSRYIYDLYYKRKIISRDLYDYLLKNKYADGNLIAKWKKPGFEKLCCLRCIQPKDTNF-GTTCICRVPKEKLVECVHC-GCR Mydma KPPPDGWELIEPTLDELDAKMREEGKRKVEALWPIFRLHHQKSRYLYDLFYKRKAISRELYDYCVKENIADANLIAKWKKQGYENLCCLRCIQPRDTNF-GTNCICRVPKPKLVECIHC-GCR Neucr2 KPPPEGFADIEEDLLIFANKMKDDNIPKHQAKWPIFQISHQRSRYIYELYYEKEAISKQLYEWLLKNGYADAMLIAKWKKNGYEKLCCLRCIQTKETNF-NSTCICRVPKAELVQCVSC-GCR Orpsp11 --------------------------------------------------------------------------------------------------------------------------- Pench1 KPPPAGFDDIEDTLLEFSNKMKDEGKKKYEVLWPIFQISHQRSRYIYDLYYEKEAISKELYDFLLKNKYADANLIAKWKKQGYEKLCCLRCVQTKETNF-NSTCICRVPKAQLIQCVSC-GCN Phybl2 KRPPQGFDEIEPTLDEFAKKMKEEGKRIVESSWPIFRIHHQRTRYIFDLYHKRKAISRELYDYLLKYKYADANLIAKWKKPGFEKLCCLRCVQPRDTNF-GTTCVCRVPKEKLIECVHC-GCR Picst3 DPAPDGYSKIEPTLKKLQARMKEKTKSKTQLLWIIYQLNHQISRYVYDMYYKKKLISRELYDWLLLQSYVNSELIAKWKKQGYEKLCCVHCILVLDKNH-KNPCICRVPKAKLLQCVTC-GCR Plicr1 KNPPEGYEDIEAILDDYAKKMRDEGKRKSESLWPIMRISHTRSRYIYELYYKREAISKELYDWLLKEGYADANLVAKWKKPGYEKLCCLRCIQTRDMNYQGSTCVCRVPKAQVVECVHC-GCR Polpo KKYPEGWEELEPKLDEFQQQMREEGKRKVEVLWPIFRIHHQRSRYIYELFYKKDGISRELYEFCLNEGYADKNLIAKWKKIGYERLCCLRCIQTKDHNH--STCICRVPKDKLVQCVQC-GCK Pucgr2 KPPPEGFEEIEGVLDEYERKMRDEGKRKNESVWPIIRINHTRSRYIYDLYYKREAISRDLYEWLLEQDYADANLIAKWKRTGFEGLCCARCVQSRDMNYAGSVCICRVPKAQLVECVHC-GCR Punst1 KKPPEGFEDIEQILDDYAKKMRDEGKRKAESLWPIMRITHARSRYIYELYYKREAISKELYDWLLKQEYADAGLIAKWKKTGYEKLCCVRCIQSRDMNYQGSTCICRVPKAQLVECVHC-GCR Rhior3 KRPPEGFDEIEPTLEEFARKMRDEGKRVVESTWPVFRIHHQRSRYIYDLYYKRKIISRDLYDYLIKNKYADANLIAKWKKPGFEKLCCLRCIQPKDTNF-GTTCICRVPKEKLPIGILAQGEK Rhoto1 KPPPEGFEEIEDILEEYSRKMRDEGKRKNEALWPIMRITHTRSRYIYDLYYKREAISKKLYEWLLKQEYADANLIAKWKKSGYEKLCCARCIQSRDMNYAGSTCICRVPKAQLVECTHC-GCR Rozal11 RKIPEGFDLIEPTIKEFERKMREDTKRAVESPWGVMRVHHQRSRYIYDL-YKRKAITKEVYDYCLNEGLADRHLIEMWKKPGYENLCCLLCIRTTDTNF-GGTCICRVPKSQRFQCPNC-GCR Sacce1 KPAPDGFEKIKPTLTDFEIQLRDLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNN-GSTCICRVPRAQLHQCVHC-GCR Salro RPPPEGWELIAPTLEQLDQKLREEGKRKCETLWPVFRIHHQKSRYIFNLYYKRKAISKELYDFCVKEGHADPNLIAKWRKPGYESLCCLACIQTRDSNH-GTTCICRVPRSKLFECVRC-GCR Schco3 KKPPEGYEEIEAVLDDYAKKMRDEGKRKAESLWPIMRISHTRSRYIYELYYKREAISRELYDWLLKEGYADANLIAKWKKTGYEKLCCVRCIQTRDMNYQGSTCICRVPKAQIVECVHC-GCR Schpo1 KRPPDGFDEIEPTLIEFQDRMRQKGT-KTEMLAPIFQLHHQRSRYIYDLYYKREAISTELYNWLLKQNYADGNLIAKWKKPGYEKLCCLRCIQTAESKF-GSTCICRVPKSKLVRCTHC-GCN Sorma KPPPEGFADIEEDLLIFANKMKDDNIPKHQAKWPIFQISHQRSRYIYELYYEKEAISKQLYEWLLKNGYADAMLIAKWKKNGYEKLCCLRCIQTKETNF-NSTCICRVPKAELVQCVSC-GCR Sphar KPPPDGWDLIEPTLLEFEQRMREEGKRKSESTWPIFRVHHQRSKYVYDLFYKRKAISKDLYEYCLKEKYADANLIAKWKKSGYENLCCLRCIQTRDTNF-GTQCICRVPKKKLIECVHC-GCR Spipu1 KPPPEGWDLVEPTLTELQQKMREEGKRKSESLWPVFRLHHQRSRYIYDMFYRRKAISRELYDYCLKEGYADGALIAKWKKVGYEKLCCLRCIQPKDTNY-GTMCICRVPKDKLIECLHC-GCR Sporo1 KPPPEGFDEIEDILEEYNRKMRDEGKRKTESLWPIMRITHTRSRYIYDMYYKREAISKELYEWLLKQEYADANLIAKWKKQGYEKLCCARCIQSRDMNYSGSTCICRVPKAQLVECTHC-GCK Stehi1 KKPPEGFEDIEGILDDYAKKMRDEGKRKTESLWPIMRISHTRSRYIYELYYKREAISKELYDWLLKEGYADANLIAKWKKPGYEKLCCVRCIQSRDMNYQGSTCICRVPKAQLVECVHC-GCR Tapde11 --------------------------------------------------------------------------------------------------------------------------- Thetr RRPPQGFDDIVPTLDQFEEEMRRVGKRKVQLTWEVLKLHHARTRYVYNLFYVRKVISRELYQWLVDEGYADALLMAKWKKAGYEKLCCLSCIQTRDHNF-GTTCICRVPRAQLVECAHC-GCR Treme1 KPPPEGFEDIQEVLEDYDKKMRDEGKRKVESVW----INHARSRYIYDLYYKRELISKELYDWLLKNGYADANLIAKWKKNGYEKLCCVRCVATQDMNFKGSTCICRVPKTQVVECPHC-GCR Trire2 KPPPEGFSDIEDDLLVFANKMKDPPGPKHMAQWEIFQIAHQRSRYVYDLYYEKEAISKQLYEWLLKNGYADAMLIAKWKKQGYEKLCCLRCVQTKETNF-NSTCICRVPRAQLMQCVSC-GCR Umbra1 KRPPEGFDELEPTFREFDKKMRDEGKRKVESVWPVFRIHHQRSRYVYDLYYKRKAISKELYDYLLKNSYADANLIAKWKKPGFERVCCLRCIQPKDTNF-GTTCVCRVPKAKLVECVHC-GCR Ustma22 TPPPEGFDEIQDMLDEYDRKMRHQAKRKVETLWPIIQINHTRSRYIYDLYYKREAISRELYDWLLKYQYADANLIAKWKRTGYEKLCCVRCIQSRDMNYQGSTCICRVPSAQLVECVHC-GCR Walse1 KQPPEGFEAIEQILDDYSRKMRDDGKRKNETLWPIMRISHTRSRYIYDLYYKRKQISKELYDWLLKQGYADANLIAKWKKQGYEKLCCTRCIQSRDMNYEGSTCICRVPKAHLFECVHC-GCR Zygro1 TAPPPGFEKIKPALDEFESQLRQIAAKKDENPWEILRISNERSRYIFNLFYKRKAISRDLYEWLLKNRLADRQLIAKWKKKGYEKLCCLKCIQRKETNH-GNVCICRIPRAQLHQCNNC-GCH [Cluster2059.fasta_al_trimmed; alignment length = 356] Allma1 WLQPILVALAVIFVLQRLIAFFHPCHAGGGGERVLWMAVRAVVVYTGDVTAADILDHAENRFDLT-VDVEFEYLSLVEDSTYPRVTLLGQSLGSVVLAWDAIAKPDLFIDTMGYAFTYPLV-KLLCPVIAYTHYPTISTDMIAVVTDRIKLVYYRLFARLYSWCGRHADMVMVNSSWTANHIHALFTVYPPCGTAAFLD-LPLAVSIAQFRPEKNHLLQIDAMAL---LVVMGSARHAE-DTARAVLE-RAREKGIDHVEVVVNAPWKEVLGAASVALHTMRDEHFGIGVVEAMAAGAIPLAHRSGGPKADIVV-PTGFLAESEEYAYTMDEADIQENARLAVAERFSDATFEKAF Ashgo11 LVVCIVSGLILAVLLASAFGFFHPCNAGGGGEKVLWKAVETTVVYTGDTTGARILSNVEHRFGSQ-LDIVFIFLRWVESRTWPRMTLLGQALGSIVLSIEAACPPDVWCDTMGYPFGYPFV-SWLIPIITYTHYPVVSIDMLDKLRMMAKFLYWRIFMRCYTFAGSFVDLAVTNSTWTYNHINAIWIIYPPCSTENLVIENAHAVVIAQFRPEKRHALILRSFSNFVKLLMLGSTRGQE-DRDYKLEQLAYSELAIPKLEFITDCKYEKMLQESSFGINAMWNEHFGIAVVEYAASGLITLAHASAGPLLDIIV-PTGFFFKD--FPTQLTDEEISQRAKRCVLHKFSDLKFSEDW Aspfu1 TLLALLATCVL-LLISRVIGFFHPCNAGGGGERVLWEAVRATAIYTGDVNKMAMLERVENRFNIQ-LHVVLLYLTYVLSSMYPYMTLLGQSLGSLVVAYDAFLVPDVFIDTMGYAFTLAFC-KMLVPTGAYVHYPTISTDMLQSLD--VKRKYWLAFARLYGWVGGHVDVVMCNSSWTSAHIRTIWVIFPPTAVSEIESTITVILYIAQFRPEKNHPLVLRSFARFLSLVLMGSVRHSSPDETHNLRL-LAHELRIRDTTFVCDASWPTILRSASVGVNAMWNEHFGICVVEYQAAGLISVVHDSGGPREDIVI-DTGFRASSDEFAAALPAEEMRQRARKSA-LRFTEEEFSQKW Aurde31 LLLLPVFLAVLVSVLDALVGFFHPCNAGGGGELVLWTAIKHIVVYTGDASKEEILAKVNSRFNIS-LDLHFVFLHWVEDATWPRFTLAGQSLGSMLLAWEAMLVPDLFIDTMGYAFSFHVV-RALIPVAAYVHYPTISSDMLARVAERAKLLYYRVFAFFYANALQNASFLMVNSTWTKNHVDAILIVYPPCNTAVIAR-AELILSVQQFRPEKDHALQIRALAALFELVLVGGARNAD-DVARALKE-LVKELGLDDVIFVVNAEYIQLLANASVGISTMVDEHFGINVVEYMAAGLIPVVNESGGPQQDIVV-PTGFHATDASYARGMPEDAMRARARAHAVKTFSVPEFTKAW Batde5 ---------MTLWLLESNIAFFHPCDGGGGGERVLWTAINAIVVYSCPSTPNELLIHIKKQFDIV-VDIRFVQLEYLEAKRYKRLTLLGQSLGSIITGMEAMLVPDVFVETVGYAFIYPIA-RFFTKVVSYVHYPTISLDMLQKVQNRMKLLYYRAFSVLYGYAGSFSNAVMVNSSWTYGHINHIWIVFPPCFTQSLSN-LTLILSIAQFRPEKNHTLQLEAFSLLLCLVLVGGVRNKD-DSRRELRL-LATKLGIEEVKIIENASYPDILAKSLIGLHTMSNEHFGISIIEYMAAGVIPIAHNSGGPKMDIVK-PTGFLATTQEYSDTLSSESIQKAARESVIGRFSDSIFCLDF Botbo1 AAISALASTTALVVLLQYAGKGGKTNAGGGGERVLWAAIAHLVVYTGDASKEQIIKKVQERFNIN-LSLAFVYLKLVDDKTWSHFTLLGQSGGSVLLGWEALLVPDIFIDTMGYAFTFFLL-RLLIPIGAYVHYPTISTDMLARVRDRAKLLYYRAFAFCYSRSLSLADNIMVNSTWTKNHVDRLLLVYPPCNTDALAK-LPLILSVAQFRPEKNHMMQLQALRALFDLVMLGSARNEE-DTQRALQR-TAHELGLAKVKFVLNAPYSELLARSSIGLSTMVDEHFGINVVEFMAAGLIPLAHASGGPLLDIVM-PTGFHASTAEFGESLRKTEMRKRARQ-SSERFGTKEFEKGW Botci1 GATPLIV--LLGGVLERVVGFFHPCNAGGGGERVLWAAVLATIVYTGDVDKSQIIARVKDRFNIQ-LHITFLYLTWVLASTWPHFTLLGQSIGSLILAWDAFVVPDIFVDTMGYAFALGFC-KILVPTGAYVHYPTISTDMLGSLDPTAKKLYWKIFAKFYTWVGASIDVVLTNSNWTLDHITSLWAVFPPVAVEELEEKISVLLYIAQFRPEKNHTLILTAFAAFKALILIGQRRC----------------------------------------------------------------------------------------------------------------------- Caeel YLVPLIIALIIPF-----VAFFHPCNAGGGGERVLWAAIRTMFVYSGDATKEQILLKARQRFGIE-LDIQFIYLHLVEARHYKHCTMLFQALAGLILALEAWMVPAVFIDSMGYPLSLPAF-RL-SKVVAYVHYPTISCDMLDVVESRGKLTYYRLFACLYWLAGKAAHVGMVNGSWTQRHITSIWIVYPPCDVEAFLNIESVLLSVGQIRPEKNHKLQLEVLHDVKELCIAGGCRNEE-DQERMLKN-EAEKLDISELIWQLNVPYEDLLSKALISIHTMHNEHFGISVVEAMAASTIILSNDSGGPRMDIVK-DVGYLSITEEYVEEEGLKKTRKYARKSL-TRFGEAAFETHW Canalb1 --MYLILL--VVLILASEYGFFHPANNGGGGERVLWQAVKATVIYTTNAQPLDILNKANKKFQIDGLDVVFIYLRLIDGNYWKHFTLIGQLFGGILLSLEAMLSPDVWIDTMGLPSSYLLV-SLSIPILAYTHFPILQEDMFGKLKFQGKFIYWSILYYFYVYLGSKVNIALANGSWTFNHLSKIWVLYPPCGTEFLIKQANLLLYLAQFRPEKRHALLLKEYSNFLSLVFAGSCRTAD-DTATFLQE-QVAKLDL-SVEFRIDISYDEVLSSCKFGLNAMWNEHFGIGVVEYMARGCTPIVHASAGPLLDMI--GGGFFFKSIDYPTTIIEDSMRQIDQNRVAEKFSNKAFNKKW Cangl FVLPVVRVPMLDLT----YGFFHPCNAGGGGEKVLWKAVQETVIYTGDSSPKEIIANVIKRFDYE-MDVQFVFLKWVDGSTWKHLTLVGQAMGSMLLTIEALFVPDIWLDTMGYPFGYPVV-RWLLPVMTYTHYPVISSDMIHKIEIELKLIYWKLFMKWYQYVGKFVDVAITNSTWTGNHIRSIWVMYPPCSTEKLV-KNSSAVLIAQFRPEKRHKLVIQAYSDFISLVLIGSTRSEE-DRAYTLKSWAFDTLKIPKLTFKTDCSYDDILAESTFGINAMWNEHFGIAVVEYAAAGLISLVHASAGPLLDIIV-PTGLFFKDNNYGSSLSIAEISERAKECASNKFSDNTFNHAW Capow ---------------------------------------------------------------------------------------------------------------MGFAFVLPLF-RWLCKVGCYVHYPTISTDMIARVRDRGKLAYYRGFALLYSLVGSCAELVMVNSSWTRGHVAQLWVLYPPCNTTLLRA-FPLIVSVAQFRPEKDHALQVRALAEALRLALVGSCRHAD-DQARSLRK-LAHELGVEHVELLVGVSHEVLLAGAVGGMHTMWNEHFGIGVVEYMAAGAVAIAHHSGGPLMDIVT-PTGYLATTEEYAQAMKDSEMQERARASVSSRFSDEVFACGF Catan2 FALPLLAGLA--FL----LAFFHPCHAGGGGERVLWVAIRACIVYSGDATPADILSQARNRFGIT-IDIQFVFLRLVEAATYPRLTLIGQSLGSVLLACEAV--PTVFIDTMGYAFAYPAV-RFLCPILAYTHYPTISTDMLRVVESNAKLWYYRLFARAYGWCGRHVTLAMANSTWTYNHLAHLWIVYPPCDTSAFEQ-LSAIVSVAQYRPEKNHALQIESFAQLLNLIMIGGCRDAG-DTQRDLER-LARDCNVADVRILRNVALNELLGSGMIGLHSMVDEHFGISVVEAMASGLVTVANNSAGPKEDIVV-PTGYLASTDEYAQDMSQHDIVDAARKSV-KRFSEEAFEREW Cioin IILPCLACLKILV-----IGFFHPCNAGGGGERVLWCAVRAIVVYTGDSTASQILNKASSTFGIT-LSVDFVFLRWVEATRYPILTLLGQSMGSVWLGVEALCPPDVFLDTMGYAFTLPLF-KYICRTGCYVHYPTISTDMLNVVECQCKLIYYRAFAFMYGVAGRCSEAVLTNSSWTLNHINQIWIVFPPCDISGFLE-IP-VLSIAQFRPEKNHSLQVESFHKFLSLLMVGGCRNEG-DESRELKS-LISKLNLQEVEIRTNISFGELLSVAHVGIHTMSNEHFGIGVVEFQAAGVIALANNSGGPKMDIVK-ETGFLAHDTTYSESLTVEKILGSARAAC-KRFSEQEFKQHF CocheC53 LFVPALVAALF-LLLARVVGFFHPCNAGGGGERVLWAAIRAHIVYTGDVDKAEILKRVKDRFNIQ-LYVHFLYLTWVLASRWPRFTLLGQSLGSLILAYDAFLVPDIFIDTMGYAFALGLS-SFLVPTGAYVHYPTISTDMLDSLQ--AKKIYWELFAKLYSKVGSTIDVVMTNSTWTQGHVKSLWVVFPPVAVEEVAEAVQVLLYIAQFRPEKNHQLILEAFASFVQLVLIGSVRNSHDDAKRQLRL-LAHELHIKDVEFICDAPWPLMMRKSSVGVNAMWNEHFGIGVVEYQAAGMISVVNNTGGPKLDIVV-ETGFHATTQEYADTLSPQEMRRRARKSA-ERFTDKTFADKW Coere1 LVLAVPIILALGFVEEATAGFFHPPNAGGGGERVLWTMIKAIVIYSGDVTRETLVRNVQRKFGIQ-IRIYVVELSWV-DYKFPRFTLLMQSLGSAILVCQAFFSPDLFIDTVGFAFTYPTV-ALLVPIVSYTHYPTISSDMQTMVSLRLKSLYYSIFAKMYGFSGSFASTIMTNSSWTHAHIVDLFVVYPPCDTNVLAK-FPLIMSLAQFRPEKNHRLQVTAFAKFLNLVILGGARNIE-DEARLLRQ-EAKTLGIDRVHVIVNAPWSQVLRLSKIGIHTMRDEHFGINIVEMMAAGQLTIAHDSAGPKLDIIT-PVGMLASDSEFAQNAEAPVIRKAARHAATTRFSEAAFCTAF Conco1 YFLPILFIPHAIIFLNSLVGFFHPCAAGGGGERVLWQSVKFCAIYTGDLTKEEMVNRVKDRFNIS-LDIDLVHLKWVEASKYPILTILGQSLGSVLLGYEAILIPDVFIDTMGYSFTYPVV-KLLVPVLAYVHYPTISAEMIASAQSQLKLVYYKVFAWIYAWTGSFCDQAMLNSSWTLGHISAMWVVYPPCDIDSFTS----IVSLAQFRPEKNHALQLHTLATLFQLYVMGSVRNDA-DQKRELME-LREELNLTNVEFVVNASYTEILSTSLIGLHTMKLEHFGISVVELMCSGLITIANDSGGPQMDIIP-PGGYLASTNEYSESLGEDEIRKNAIEWC-SKFSNEEYEKGF Conpu1 FVLAALLPVLLSYVLRALIGFFHPCNAGGGGERVLWTAIARIVVYTGDASKEEIIAKVEARFDIT-LDLHFVFCDYVEDAAWPRFTLLGQSLGSMYLAWEAMLVPDLYIDTMGYAFTFHVV-RRLCPVGAYVHYPTISTDMLARVRERGKLWYYRLTMYYYALSLRSASFLMANSTWTKAHVDAILIAYPPCDTREMER-YALVLSVAQFRPEKDHAAQLRAFAELLELVLLGGSRNAG-DSARGLRE-LAKSLGIDDVSFVLNAPYPTMLARASVGLSTMVDEHFGINVVEMMAAGAIPVAHASAGPLLDIVV-PTGFHATTSTFADTLPPAELRQRARQLAVSKFSEDAFWASW Copci YHLAPEITA-LAKILSEESGSFIP--IGGGGERVLWTAIASIVVYSGDASKEQIMSKIKSRFNIT-LDLHFVFLKMVEDSTWPRFTLLGQSIGSIFVAWEAMLIPDLYIDTMGYAFTFPLV-AALIPVGAYVHYPTISTDMLARVKSRAKLFYYRVFMYYYALCLRTASFLMVNSSWTRNHIDSILVVYPPCDTRAMSS-FDLILSIAQFRPEKDHAAQLHAFHVLLKLVMIGGSRNAE-DANRELRQ-LARKLEIEPVEFIVNASYQVVLSKASVGLSTMVDEHFGINIVEFLAAGVIPVTHASGGPLLDIVV-PTGYHARTDEFAESLSPDEIRQRARTWAVQRFSEEEFEKGW Croqu1 FRLPPIARLIIVLLLENIIGFFHPCNAGGGGERVLWTAVAFHAIYTGDVTKEEMISKVKQRFNID-IELILVPLTLLEASYWPRFTLLGQSLGSIVVGFEAILIPDVYIDTMGYAFTYPIF-SSLIPIGAYVHYPTISTDMVKKVTNRAKLLYYILFAELYSNCLKQADNIMVNSTWTKRHIENLLIIYPPCDIKSFIN-FPLILSISQFRPEKDQIKQILSFSNF-LLILAGSCRDSE-DEKRDLKK-LVDQLGLQSVEFKVNIDYNELLSISSIGLSTMVDEHFGISIVEFMASGLIPLVHASGGPLTDII---TGYFGTTESYSQSTDQIQLRENARKISQEKFSEEVFEFEW CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 AIIPAFV--LFGIILEVIVGFFHPCNAGGGGERVLWAAIRAIVVYTGDVNKDQILTRVKSRFNIH-LQIQFLYLSWVLASTWPRFTLLFQSLGSIVLAWDAFVVPDIFVDTMGYAFALGFC-KWLIPTGAYVHYPTISTDMLDSLDPNVKRYYWKGFAWLYSKMGTTIDVVMTNSTWTQAHVTSLWVVYPPCAVEELEDAVEVLLYIAQFRPEKNHQLIVQAFANFVKLVLVGSVRDDH-DSKRKLRL-FVRELHIEDVEFRLDAPWPNILQKASVGVNGMWNEHFGIGVVEYQASGLIAVVHNSGGPKLDIVT-ETGFHASTEEFAESLP--DVRLRARQSA-KRFGEVEFDRKW Debha1 -MGYLVVIGVIACVLASKYGFFHPANNGGGGERVLWQAVQATAIYTTNSDPTLILDKVEAKFQISRLDIVFVYLRLIDGDYWKRFTLIGQLFGSMVLSWEAMLSPDVWIDTIGLPGSYLLV-SLVIPIMSYVHYPIIQPEMFNKLKFQGKLIYWSGVFYFYKYLGSLVNITLANGSWTFNHISNIWILYPPCGTETLTKNVETLLFIAQFRPEKRHSLILRQYSKFLVLVFLGSCRTPD-DTKTDLKQ-EVDDLEL-NVEFVVDCSYEDILSKVKFGLNAMWNEHFGIGVVEYMSRGVIPLCHASAGPLLDIVT-NTGFFFKDSTYPTDLISETMRENGVKSVLEKFSNGVFTLKW Dekbr2 QFPKIFSTICLGIILASAYGFFHPSYAGGGGERVLWQAVYVTLIYTFTQSVSSILTSVHKTFGLDFFTVVFMQLPIIDGNSFKFLTMAFQALGSVIAFFFAMCAPDIFIDTLGLPFSYPLA-SCFIPVYAYVHYPWVSNDMLNKLAIKLKYAYWYLLMKLYSICGSFLTESSCNSSWTLKNLLKVWIIYPPTGIDESKIQLNAFLYIAQFRPEKRHELLIKEFHKYVTLVLIGSTRSDD-DKKTHLKS-LINDFSFPEIEIKVNAAREEVLNKSEFGLNAMWNEHFGISVVEYMIYGVIPIVHASGGPLADIVV-PSGLFFQDTEFESELTDAQYRKNAISVAEKKFGISVFEQEW Dicdi VLVVPLIICIIAL-----IGFFHPCTAGGGGERVLWCAIKSIVVYTGDESDDEIFNKVKKTFDIE-LGLEFIRLKWVEASTYPRFTLIGQSLGSMILGWEALFVPTIFLDSMGYAFTFPIF-SLISTVACYVHYPTISSDMISSVKSSSKLIYYNIFSKIYQIVGSFSKLVMVNGTWTGNHIRDIWIVYPPVDVKGRKQ-LKLILSIAQFRPEKNHQLQLRTLAHLLELVLVGGVRDQA-DRDRQLRN-LSKELNIEDVEFQIGISSDQLLSEASVGIHTMYNEHFGIGVVELMAAGVIPVANNSAGPKEDIVR--TGFLASTQEYAE-AYREKMQKKARDST-DRFSESNFSNQF Dmel FLLWLLLSLVLVAL----VGIFHPCNAGGGGERVLWCAVRALVIYTGDASPNSILQKAKNVFNIA-VDVKFVFLKWIEAKNYPHFTLLGQSIGSMVVGLEALFPPDIYIDTMGYAFTYPLF-RYLSKVGCYVHYPVISTDMLKRVQQRTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWRVYPPCEVSHLKS-LQHILSVGQFRPEKDHPLQLQAIYELRTLVIVGSCRNED-DYERNMQD-LTKHLSLENVQFSVNVPYEDLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVE--NGFLATDVEYAE-VNNSEIRNAARASV-ERFSEQEFEKNF Enthi VLLTFCILLPIII-----IAFFHPCSAGGGGEMVLWVIIKVLVIFTAD---DKILEKVKSTFGFD-FLIKFYQIKSLVIKKYPFLTLFFQAIGSMICCFDALCNAEYFFDTTGCAFTYPFA-WL-AKIMTYTHYPTISTDMLNVVQKRMKVFYYKIFAYLYYLVGNLASLVFVNGTWTKNHISQLWLLYPPCD----IN-VSNIISIGQFRPEKRHLVQIEAINILVQFVVIGGARDAE-DLKREKDK-LTDIITVPETSYEQKIEY---LKNAEIGLHTMVNEHFGICVVEYMGFGVIPVAHKSAGPELDIVD--CGYLATTKEYADNDPEKT--RQAAIQKAKKFSVSAFEKQC Falba LTAAVLFFVLVPA-----IGFFHPPHGGGGGERVLWSAVAAICVYTGDAAGRHAPEHALDRFNID-L-VHLVPLVLLSPHLWPVATLVFQSLAGAFVGLEAILQPDVMIDTSGHAFAYPIW-SWATWVASYTHYPVVSSDMLEAQRAQLKIPYYRLFSQLYRLAGSYSGFSMVNSTWTSNHMAAIWIVFPPCDTKTLSA-LPLIVYLAQFRPEKDHGLVLRAFAKYLQLVFIGSIRAAPLQRQQTLDA-LLQRQGYWDVRFLVNAPFDLVLGQSQVGVHAMRQEHFGIGVVETMAAGCVMVAHDSGGPQADIVV-PTGFLARTRDYARTLDGATIAGHARAHVGAAFSQQRFDRAF Fomme1 LVLAPLL---LAQVLRELVGFFHPCNAGGGGERVLWTAIALLVVYSGDAGKEEIIAKVKTRFNIT-LDLHFVFFSLVEDSTWPRFTLLGQSLGSIPLVLYAFLIPDLYIDTMGYAFTYPFV-RLLVPVGAYVHYPTISTDMLARAGANPKLLYYRAFMACYATALRCASFLMANSTWTKNHVDSLLIVYPPCETQELVD-FPLIVSVAQFRPEKDHAAQLRALAKLFELIMIGGCRNAD-DEARGLRA-LSKELGVSEVEFVLNAPHPEVLSRASVGLSTMVDEHFGINVVEFMAAGVIPVVHASAGPFIDIVV-PTGYHATTQTFATSLSPAEMRLRARTWAVERFSRAGFERAW Fusgr1 ALVPLAI--LIAILLALMVGFFHPCNAGGGGERVLWAAIRATVVYTGDVTKDAILSRVKTRFNIE-LHMTFLYLSWVLPSTWPHFTLLGQSLGSVVLAWDAFLVPDVFIDTMGYAFALGLC-KFLIPTGAYVHYPTISTDMLESLDVKAKKNYWKLFAVIYSWVGSSVDIVMTNSTWTQGHIKSLWVVYPPTAVREMENEVEVIVYLAQFRPEKNHQLILRSFATFVKLILIGSVRDDS-DAKRQLRL-LANELGIKNVKFHLDAPWSEVLRKASVGVNGMWNEHFGIGVVEYQAAGLISVVHDSAGPKFDIVV-PTGFHATTEEFAQSLP--DVRLRARESA-KRFTEEEFAKKW Galma1 LLLQP-VFI-IWLLLSELVGFFHPCNAGGGGERVLWTAIAGMVVYSGDATKEAILSKVKSRFDIS-LDVHFVFLQLVEDSSWPRFTLLGQSLGSMYLAWEAMLIPDLYIDSMGYAFTFHVV-AHLIPIGAYVHYPTISTDMLARVKSRGKLLYYRFFMYYYTQSLRTSNFIMVNSSWTKNHVDSILIVYPPCDTREMAQ-FPLILSVAQFRPEKDHQAQLMAFHKLLTLVLVGGSRNEG-DARRQLRK-LAQNLDIEPVEFVINASFPIVLSNASIGLSAMVDEHFGINVVEFMAAGVIPVAHASGGPLKDIIV-PTGYHALTEEFAESLSPEEMRWRARAWAVQRFSEEDFERGW Ganpr1 FLLGT-IALALLR-----LAFFHPADAGGGGERVLWVSVKALVIYTRDLSADEILERVKVQFDIT-LSVDFVWLKWILAERYPTITLMGQSLGSLVPAYEALLRPDVFIDTTGFAFTLVLA-KYGCRTIAYVHYPTVSKDMLRKVENRVKLQYYRFFASLYSLAGSSVDHAMVNSTWTKNHIDSLWLVYPPCNVGTLAT-TPLVVSVAQFRPEKAHMLQVEAFA-LARLVLIGGCRHEG-DWKLDLKQ-RAIELAVVDIDFIINAEYSRLLKNGLIGLHTMTEEHFGIGIVEYMAAGLVAIAHDSGGPKTDIVI-ETGMF----------------------------DLTYECD- Gloin1 ----------------------------------------------------------MSRFSIK-LNLFFVFLNWVEDVRYPRFTLLGQSLGSTVLGFEALLTPDFYFDTMGYAFTYPLA-KKMCKVGAYVHYPTISSDMLSKVQEMGKILYYRVFAYLYSLAGSFSDIVMVNSTWTKGHIDQLWIVYPPCDTASLTK-LPLIVSVAQFRPEKDHQLQLQSLRCLLSLVLIGGSRNKD-DEDRKLKE-LCKTLDIEDVTFEINASFERLLSKAKIGLHTMWNEHFGIVVVEYMAAGLIPVAHNSGGPKMDIVI-PTGYLASTEEFATSLSEEEVQINARENVIGKFSESVFQESI Hisca1 TLVTLLALFLT-AIRARIIGFFHPCNAGGGGERVLWAAVRATAIYTGDLNKTTMLERVENRFNIR-LYIVFLYLSYVLSSIYPRFTLLGQSLGSLILGYDAFLIPDILIDTMGYSFVLAFC-HFLIPTGAYVHYPTISTDMLSSLD--AKRQYWHAFAKLYGRVGGTIDVVMCNSSWTAAHIRSLWVVFPPVAVSELES-IEIILYIAQFRPEKNHALILRAFSRFLNLILIGSVRHSSPDETHNLRL-LAHELKIRDTTFLCDASWPTILRHASIGVNAMWNEHFGIGVVEYQAAGLISVVHDSGGPRQDIVV-DTGFRATTPEFAAALPIEEMRLRARRSS-KRFTDEVFAERW Klula1 FVTYVFGSLLAGLILASELGFFHPCNAGGGGEKVLWKAVETSVIYTGDVNGSDILNSVRRRFEYD-LDIVFIFLQLVESKSWPKFTLLGQAYGSIILSIEALLAPDYWIDTMGYPFAYPFV-SLFIPIVTYTHYPVISTDMLQKLKTMGKYVYWKIFMLAYKFSGLFVEIASTNSTWTYNHIKSIWIIYPPCSTESLIEGCDKAVVIAQFRPEKRHELILSSFSSFIDIIFIGSTRNVE-DREYTLKKYAFEALKIPTVDFKTDCKYDDMLYSSWFGINAMWNEHFGIAVVEYMASGLIPLCHASAGPLYDIVV-PTGFFFID-KYSSKLNTVQISNRAKMCSLSKFSDSEFERSW Lacbi2 LILSPLVYISLWLILEHLVGFFHPCNAGGGGERVLWTAIAAMVVYSGDVRKENIIDKVKARFDIA-LDLHFVFLDYVEDSTWPRFTLVGQSIGSMFLAWEAMLIPDLYIDTMGYAFTFHVV-SLLIPVGAYVHYPTISTDMLARIKSRGKLLYYRTFMYFYAFSLRTASFLMVNSSWTKDHVDAILIVYPPCDTREIAA-FPLILSVAQFRPEKDHAAQLHAFQLLLKLVLVGGSRNAG-DESRSLRK-LAVELGIHEVEFVVNAPYPTVLSSASIGLSTMVDEHFGINVVEFMAAGVIPVAHASGGPLKDIII-PTGYHAATEEFAGTLDSEELRMRTRTWAVQRFSEEEFEKGW Lenti61 MILALVTFV-LALLLSGLVGFFHPCNAGGGGERVLWVAIAAIVVYSGDTTKHKIIQKVKARFDIE-LSLDFVFLELVEDSTWPRFTLLGQSIGSMYLVWEAMLIPDLFIDTMGYAFTFPVV-SLLIPVGAYVHYPTISATMLSRVESRGKLLYYRLFMYYYAYSLRQARFIMVNSSWTKNHVDSILIVYPSCDTRQMAV-FPLILSIAQFRPEKDHAGQLRSFHKLLELVLVGGSRNVG-DATRELRL-LAKELDIQDTEFVVNASYPQVLSRASIGLSTMVDEHFGINVVEFMAAGVIPVAHASGGPLLDIIV-PTGYHATSETFAETLSTESMRKRARTWAVQKFSAEEFEKGW Malgl1 -MLLVFVACTVGVILQDLVGFLHPSHGGGGGERVLYEAILHHVVYTGDVSKQEMLDKVRTQFGIE-LNVAFLPLALVGDNFWSMFTLAGQAIGANRMGYSAMLVPDVFIDTAGHAFTYSAV-KNFVRLGAYIHYPTISTDMLQRVRQRAKYVYYRLFAAVYGSALRHADVIVCNGHWTRAHVMDLLVVYPPCQTASFTS-LPLLLSIAQFRPEKEHELQLRIVHGLLQLTLIGSCRHDA-DKKRALER-LAKELMIENIEWCVDAPFTTMMRTASIGLSTMVDEHFGIAVVEYMAAGLLTLSHASAGPLMDIAV-PTGFHASCDEYIDTMPPSTVRRIARERAASSFSDVEFHRRW Mellp23 TRSPPLIKLTIILLINQTIGLFHPCNAGGGGERVLWTAVSFHAIYTGDVTKSEMINKVKQRFDID-LDLILIPLKLVESSRWPRFTLVGQSLGSMVLAYEAILIPDIYIDTMGYAFTFLVW-SALIPIGAYVHYPTISTNMLKRVTDRLKVLYYLLFAEVYSVCLKRADYLMVNSTWTKTHVDKLLIVYPPCDVKTFTS-FPLILSISQYRPEKDQLKQIESFAKFSSMILVGSCRNQE-DLDRSLRN-RCKELGIQSVELRVNVGWDELLGSSLVGISTMVDEHFGISIVEFMAAGLVPLVHKSGGPLMDII---TGFFGTDDSFAARLSETDIRSEARRVSVEKFSVKVFESAW Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAKSKLVFVNSSWTKGHIDELWLLFPPCNTEKFLQ-IS-VVSVAQFRPEKDHKLQVESFAKFVELTLVGGVRNQA-DRDRSLLE-LTRSLGVEEVEFKVSIPYPELLSDSLVGLHTMWNEHFGIGVVEFMAAGIVPIAHNSGGPKLDIVV--AGFLASTEQYSDEMGEEEMRRRGRDHVKGTFSDETFRKVF Monbr -LLLSFVFLAVQAVQRDLVAFFHPCNAGGGGERVLWSAIQAVLLYSGDATADMILTRAAERFGLV-IDVTIAFLHYVEAHHYPHFTMLLQSLGSLVLGLEAIHRPDVFLDTMGYAFVLPLV-RLLSRVGCYVHYPTISTDMLSKVRDRVKLLYYNIFALAYGLAGAFAAVVMTNSSWTHNHIRQLWVVYPPCDTSGLEH-LDIIVSVAQFRPEKDHALQ---IEAFALLVLVGGCRNEG-DARRSLRA-QATALGLQSIDFRVNVDYAELLSRAMIGLHTMRDEHFGIGVVEFLAAGPIALAHNSAGPKQDIVI-PTGFLAETQEFANDMPEGQLRARARAAVSNRFSDEAFKAAF Morel2 TFIG---LSVTVLVFEELAGFFHPCNAGGGGERVLWTAIRDIVVYTGDVNKQDILERVRTRFNID-LDVGFEFLKWIEDAKWPRFTLIGQSIGSMVLGWEALVVPDIWIDTMGYAFTYPAA-RLFCQVVAYVHYPTISSDMIGRVASRLKLVYYRLFALIYALVGKFCHTVMTNSSWTKGHIDSLWVVYPPCDTEAFKD-FPLVVSVAQFRPEKGHALQLDAMAQLLKLVMVGSARNES-DNNRQLNE-KAAQLGITDVTFVVNAPFSELLARSKIGIHAMLDEHFGIGVVEYMAAGLVPVAHNSAGPKMDIVR-PTGYLASTQEFADSAGDSTMQLRARDSVQERFSEKVFGEGF Mucci2 ALL---------VLLQDLLGFFHPCNAGGGGERVLWTALRDVVVYTGDATKEQIINKVKTNFNIS-LNLQFVYLTLTEDARYPRFTLILQSLASLIIGYEAILVPDVFFDTMGYAFTYPLV-HYFAKIATYTHYPTISSDMVNRVYERGKLIYYRIFAKIYGFCGSFANIVMVNSTWTKGHIDQLWIVYPPCDTERLNA-LPLIISVAQFRPEKDHSLQLKSLARLFELVLMGSSRNEG-DAKRGLRK-EAVDLGIHDVRFEINASYDLLLGMSRIGLHTMWNEHFGIGVVEYMAAGLIPVAHKSGGPKLDIVV-ETGFLADTDTFAESLTEAEMAANARASASDRFSEETFSSDL Mydma FALSALICIIILL-----VGFFHPCNAGGGGERVLWCAIRALVVYTGDSKPEDILKRAKERFNIE-INVHFVYLHWVTAELYPVLTLLGQSLGSIVLGFEALFTPNIYLDTMGYAFTIPIF-KYICYVGSYVHYPTISTDMLEKVLQRLKWIYYNIFALCYGLSGCCNDIVMVNSSWTLNHIISLWVIFPPCDTKTLMN-ISIIISVAQFRPEKNHMLQLEIFEKFLKLLLVGSCRGEE-DNNRLLKK-KAELLKINQVEFHLNISHEKLLTVSTIGLHTMKDEHFGIGVVEFMAAGLIVLAHNSAGPKMDIVI-NTGYLASTEEYVENLLPSEICMNARDSVKKRFSEETFEKLF Neucr2 TIGPLLA--LF-IILEVVVGFFHPCNAGGGGERVLWAAIRATVVYTGDVSKEAILSRVEQRFNIH-LHVNFLYLSWVLASTWPYFTLAGQSFGSLIMAWDAFLVPDIFVDTMGYAFALGFS-RFLVPTAAYVHYPTISTDMLESLDPAAKKIYWQLFARLYSLMGASVDVVMTNSTWTQAHIEKLWVVYPPVAVEELEQEVEVLLYIAQFRPEKNHQLIVQAFAEFLKLVLVGSVRDDY-DSKRKLRL-LVNELHIKDVEFHLDASWPDILRRASVGVNGMWNEHFGIGVVEYQAAGLISVVHDSGGPKLDIVV-ETGFHATTKEFAESLP--NVRLRARKSA-KRFTEEEFARRW Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ATLVLTATAVL-LVIARAIAFFHPCNAGGGGERVLWEAIRATAIYTGDVNKATMLEKVENRFNIR-LHVVLLYLTYVVSSSYPYMTLLGQSLGSLIVAYDAFLVPDVFVDTMGYAFTLALC-KWFIPVGAYVHYPTISTDMLASLD--TKRRYWEIFAKLYGWVGRQVDVVMCNSSWTAAHIRTLWVVFPPTAVTELQSNIVVLLYIAQFRPEKNHPLVLRSFARFLQLVLIGSVRHSSPDETHNLRL-LAHELRIRDTTFLCDASWPVMLRTASVGVNAMWNEHFGICVVEYQAAGLICVTHDSGGPREDIVV-DTGFRAETEQFAAALPEAEMRQRARRSA-QRFTEEEFSRKW Phybl2 -------------VLRELLGFFHPCNAGGGGERVLWTAVRDVVIYTGDATKEQILYKVKVNFNID-LDIIFVYLTLVDDSRYPRFTLALQSLASLVLGFEAVVVPDIYFDTMGYAFTYPFI-SFIVKIFAYVHYPTISSDMLQRVYEQGKLIYYHLFAKAYGFCGSYADVVMVNSTWTKGHIDQLWIVYPPCDTDRLNE-LPLIVSVAQFRPEKDHSMQLKAVAQLLELVLIGSSRNQG-DEDRRLRQ-EVVSLGIDDVRFEINASYDVLLGKAKVGLHTMWNEHFGIGVVEYMAAGLIPVAHNSAGPKLDIVT-DTGYLADSDGFASSLSLEEMASNARASASDRFSEVAFSSKF Picst3 ------------MILASIYGFFHPANNGGGGERVLWQAVGATVVYTTNAEPLQILQKAEDKFQVSGLDIVFIYLRLIDGAYWKHFTLIGQLVGSMLLGLEALLTPDIWIDTIGLPGSYLSV-TFILPILAYVHYPIIQSDMFNKLKFKGKFVYWSMVYYFYVYLGSTVDVTLANGTWTFNHISNIWKLYPPCGTETLTKEVNLLLYIAQFRPEKRHSLFVDEYAQFLKLVFLGSCRTAD-DTATLIQS-KVEKAGL-QVEFIVDCSYDEVLSRAKFGLNAMWNEHFGIGVVEYLARGVVPLVHASAGPWLDIVT-GSGFFFKSAQYPSELVSDKMRHNGLRLVKEKFSNGVFSESW Plicr1 LLLPPALVV-LVLLIKSSVGFFHPCNAGGGGERVLWTAVRAMVVYSGDASKDQIIAKVKARFEIT-LDLHFVFLNAVEDATWRHFTLLGQSLGSIYLAYEALLIPDLYIDTMGYAFTLPVF-ALLVPVGAYVHYPTISTDMLARVRSRGKLLYYRAFMYVYAHCLRTSSFLMANGSWTKNHVDSIIIVFPPCDTREMAT-FKLVLSIAQFRPEKDHIMQVRAFAALLELVLIGGSRNAG-DQQRMLQA-MVQEAGLTDVEFIVNASYPVMLARASVGLSTMVDEHFGINVVEFMAAGVIPVAHASAGPLNDIVV-PTGYHAKTDEFAQTLPPVEMRARARHWAVQTFSEAEFERGW Polpo VVLLPLVLIITGV-----VDLINPSAAGGGGERVLWCSIKAIVVYTGDVTDQQIYQKIKSQFDID-LNLEFVRLSYIQ-----------------------------------------------------------------------------------------------------------------------------------------------TLHHLLEFILVGSTRDQA-DRDRALRS-LAAELKVADMQLEVGVSASMLLNEASVGIHTMWAEHFGIGVVELMAAGVITVAHNSGGPKEDIIE--TGFLATTEEYAE-ANKEKMQKAARDST-DRFSEENYYIQF Pucgr2 YQLPPPISLILIILLSLIIGFLHPCNAGGGGERVLWTAVALHAIYTGDVSKQEIIHKVKSRFGII-LDLLLVPLKLVEASTWPRCTLLGQSLGSLVLGYEALLIPDIYIDTMGYAFTFPVF-RLLVPIGAYVHYPTISNDMLQRVSRRAKLIYYIIFAELYSFCLRQAHHLMVNSSWTKNHIDRLLVVYPPCDVESFLD-FPIILSISQFRPEKDQGTQIKAFARFLSLVLAGSCRDHA-DHERQLKE-LAHQLGVSQVLFLVNVSWDQLLKESLVGISTMIDEHFGISIVEFMASGMIPLVHRSAGPLLDIVV-PTGFHADGAEYAASLSPDEIQSDARLLARTKFGVGQFERLW Punst1 LSLAPCAVIILGFLLTSLVGFFHPCNAGGGGERVLWTAIAMLVVYSGDATKEEIIANVKSKFDIE-LSLGFVFLEAVEDTTWPRFTLLGQSLGSMYLAWEAMFIPDLFIDTMGYAFSFHVV-SWLIPVGAYVHYPTISTDMLQRVRTRGKLLYYRMFMHQYAHALRRARFLMVNSSWTKNHVTSVVIVYPPCDTRQMVE-FPLILSIAQFRPEKDHAAQLRSFAELLKLVLIGGSRNTD-DAARGLKA-LAQELGVENTEFLVNAPYPVILSRASIGLSTMMDEHFGINIVEYMAAGVIPVTHASGGPLNDIVV-PTGYHARTTEFAQVMSPTEMRKRARQWAVQRFSAEEFERGW Rhior3 --------------------------------------------------------------------------------------------------------------------------------------------MVNRVYERGKVLYYRVFAKVYGFCGSFAQAVVVNSTWTKGHIDSLWIVYPPCDTERLNK-LPLIVSVAQFRPEKDHALQLRSLAKLFELVLIGSSRNEA-DANRSLRQ-LAVELGIQDVRFEINAPYDLLLASAKIGLHTMWNEHFGIGVVEYMAAGLIAVAHKSGGPMLDIVT-DTGYLANSETFADSLSEEEMASNARASASDRFSEDAFSSDL Rhoto1 LSLAVPLLS-LTLVLAKLVGFFHPCNAGGGGERVLWTALACMVVYTGDASKEQILAKVKSRFDIT-LSLHFIPLELVEDSTYPRLTLLGQSFGSVLLALEGLCVPDVWIDTMGYAFAYPLV-KYLIPVASYTHYPTISTDMLHRVSSRLKLAYYVVFARVYSWSLRKAGVVWVNSSWTRGHVEGLILLYPPCDTVHLSS-LPLIISLAQFRPEKEHSTQLHALAFLLSLVCAGSVRNEA-DAQRALRA-LARELGVEDVEFVVNAGYAEIMGKASVGLHTMVDEHFGITVVEFQAAGLIPLAHASAGPLLDILL-PTGFLAASGSFAASLPEDEIREAARRNAQERFSVRRFEEGW Rozal11 ILLG--------------VVFFHPCMSFGGGERVLYTWMKFLMILTGE------IMKIRERFDID-LLIKVVSLHLLDPLLFPIATLFFQILGSLICCAKLL-SPEVLVDTTGCAFIYPII-KLFCKIVSYVHYPFISSDMLQMVSKRVKLYYYKILSFVYCLCGSFADEILVNSTWTHNHIIELWIVYPPCGIEKLIN-IDIILSIGQFRKEKNHQLQIEAF-----LILVGGCRNEE-DYSRELKS-LANILNVSEVEFKVNVSFDELLTLADIGIHTMQDEHFGICVVEYMAAGLIPIAHNSGGPKLDIVD--CGFLAKNEEYSNSMSIRKYRENARLKIEQTFSESQFANNI Sacce1 FKKYVVSSLVLVYVYSSLFGFFHPCNAGGGGEKVLWKAVDITVIYSGDVTPENILNNVKAKFDYD-LDIFFISLKLVDSSTWKHFTLIGQAIGSMILAFESICPPDIWIDTMGYPFSYPIIARFLIPIVTYTHYPIMSKDMLNKLFKMGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWIIYPPCSTEKLVDWKQKAIVLAQFRPEKRHKLIIESFATFLKLIMAGSTRSKQ-DENYSLQDWSENVLKIPKISFEKNLPFDKILNKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVT-PTGFFFKE-RYPNKLDYDCMGARNQQYSLYKFSDLKFDKDW Salro PLVAAIPVLTVAACQRDILAFFHPCNAGGGGERVLWSAINAVIVYTGDASSEQILAKARLRFGVE-VDVTFVFLRLVEAELYPRFTMLMQSLASMLMGVEALHVPDVFIDTMGYAFVLPLF-AGLCPAAAYVHYPTISTDMLQKVAKRVKLWYYRIFAFIYGMVGGAASAAMCNSTWTYNHIDALWIVYPPCDVSQLTS-LPLVVSVAQFRPEKNHALQLRALKAFID--------------------------GKEEFQIRTNVTYEELLGRALIGLHTMKDEHFGIGVVEFMAAGAIALAHDSAGPQGDIVL-PTGFLASTEEYAENMTPQQIQTRARESVTKRFSEEQFKQGF Schco3 ----------MAFFLEPFIGFFHPCNAGGGGERVLWTAVAAMAIYSGDATKDDIIAKVQSRFAIT-LDLGFVFLQLVEDTTWPRFTLLGQSVGSMLLALEAMLRPDLYIDTMGYAFTYPIF-KIFVTCGAYVHYPTISTDMLARVESRGKLLYYRIFMHFYAVSLRQASFVMANSTWTKNHVDSILRVYPPCDTTEMAK-YPLIISVAQFRPEKDHPAQLRALYELFDLILIGGSRNAE-DAARLLRT-LAAKLGIQDIEFRINAPYPDMLGRSSIGLSTMVDEHFGINVVEYMAAGVIPLAHASAGPLLDIVT-PTGFHATTQEYAETLPPDEMRERARTAALSRFSEAEFVRRW Schpo1 -MITTLAIALF-ILYKQVVGFFHPCNAGGGGERVLWTAVKSVVVYTGDVSKAEILRRVKNTFEID-LDIVFVYLKLVSATTWHRFTLLGQSLGSMILGFEAIFAPDIFIDTMGYAFTFCVV-KS-IPVGAYVHYPTISTDMLKSLK--VKMAYWRWFAQLYSDAGSHADYVMTNSSWTRNHIASLWVVFPPCNTSELEK-IDILLYLAQYRPEKNHENVLRSFALYFELLLVGSVRGEE-DMCFHLKT-LATELNLQSVKFVVDAPWPKVLGTCSIGVNYMWNEHFGIGVVEYMAAGLIPVVNNSGGPKFDIVI-PTGFHASTSEYAETLSPQEMRINARSAC-ARFGEHVFMRDF Sorma TIGPLLA--LF-IILEVVVGFFHPCNAGGGGERVLWAAIRATVVYTGDVSKEAILSRVEHRFNIH-LHVNFLYLSWVLASTWPYFTLAGQSFGSLIMAWDAFLVPDIFVDTMGYAFALGFS-RFLVPTAAYVHYPTISTDMLESLDPTAKKIYWQLFARLYSLMGASVDVVMTNSTWTQGHIEKLWVVYPPVAVEELEQEVEVLLYIAQFRPEKNHQLIVQAFAEFLKLVLVGSVRDDY-DSKRKLRL-LVNELHIKDVEFHLDASWPDILRHASVGVNGMWNEHFGIGVVEYQAAGLISVVHDSGGPKLDIVV-ETGFHATTGEFAASLP--NVRLRARKSA-KRFTEGEFARRW Sphar LLLPALTVIILAV-----VGLFHPCNAGGGGERVLWCAVRAIVVYTGDSNGVDILRKAKKAFGVS-PLVEFVFLEWVEAKRYPVFTLLGQSIGSIILGWEAMCVPDIYIDTMGYAFTYPLF-RLLCKVGAYVHYPTISTDMLTKVQNRGKETYYKAFVYLYRLVGGLANVVMVNSTWTFDNIDTIWIVYPPCDTVGFEA-LPLIISVAQFRPEKDHELQIRALDQYLRLYMIGGCRNED-DENRNLKL-LADSLSISQISFKTNVTYSELLATAQVGMHTMWNEHFGIGVVEYLAAGVIALAHDTAGPKFDIVLEECGYRASTGQYAQDMGDAEVQTVARASVSHRFSEDMFDKKF Spipu1 CLFGLLGAVVLVLL----LGFFHPCDAGGGGERVLWVAIKAIVIYCWDGPVEQVLQKAKVQFNVD-IDVRFQTLKFLEAERYRIFTLLGQSLGSVLVGWEAMLLPDVFIDTVGFAFVYPLA-KYMCKVVAYTHYPTISADMLGKVVSGGKIWYYRLFAWLYGIVGRTADVVMVNSTWTLGHVNSIWVVYPPCNTESLQS-FSLIVSVAQFRPEKAHKLQLSAFQTLLELILIGGSRNAE-DRKRELKQ-YAEDCSIYEVEFIENAKYSTLLQKGSIGLHSMRDEHFGIGIVEYMAAGLIPVAHNSGGPKLDIVT-MTGFLAETNEFADRLPSEEMRIHARQHVVDRFSEESFSSRF Sporo1 -----------------------PSNAGGGGERVLWTALAYMVVYTGDVSKEAMIEKVKSRFGIQ-LDLHFVILSLVEDSTWKRFTLLGQSLGSVVLAAEALIVPDVWMDTMGYAFTYPLV-KFFIPVGSYTHYPTISTDMLRRVSTRLKLFYYRLFALVYRLALSCASLIWVNSTWTRQHLETLLLLYPPCDTTSLSS-LSLILSLSQFRPEKEHSLQLETLSRLFSLILAGSVRNEG-DSSRGLKR-LSKELGIERVEFRVNEGWEELFGQSGVGLHTMFDEHFGITLVEFQAAGLIPLAHASAGPLLDIL------------------------------------------- Stehi1 LLLAVPFYI----LLKSLVGFFHPCNAGGGGERVLWTAIAFMIVYSGDATKEEILDKVKARFAII-LSVHFVFLEFVEDSTWPRFTLLGQSLGSMYLAWEAVLIPDLYIDTMGYAFTFHVV-SLLIPVGAYVHYPTISTDMLARVQSRGKLLYYRLFMYHYAQALRRVSFLMANSSWTKNHVDSILIVYPPCDTRAMSS-FPLILSIAQFRPEKDHPMQLHALSKLLLLVLIGGSRNEE-DSARSLRA-LARELHVEEVEFMINASYPAMLERASVGLHTMVDEHFGISVVEFMAAGVIPVAHASAGPLLDIIV-PTGYHATTETFAETLSKDSLRQRARQWATMTFSEQEFEKGW Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------MFDKISRTVKMLYWRLFAMLYAGTGQFADIVMANSSWTMSHLSRIWIVYPPCDTKALSQ-ITVIVCVAQFRPEKDHATIIKAFAVLV-LILIGTVRNQS-DRVRALRA-LTEELHVNRVDFHEDLPWSKVLGQSWIGTNAMWNEHFGIGVVEYMAAGLLAVAHDSAGPKMDIVV-DTGYRATDLSFAERLDVAEMRRRAQKS-SARFSEDIFASAW Thetr VILGMVVVCKVVA-----IAFFHPANAGGGGERVLWKGVAAALIYTGNIPPEDILARARNRFAVE-LPI-FVFLAAVESHALLRPTMLMQSLGSMVLAGEALARAHVVIDSMGYAFTYPVF-SWIAVVGAYVHYPTISTDMLAAVVAQAKATYYRAFAWLYGFMGRRATMVTVNSSWTHGHIAALWTVFPPCDCATFLE-LPPIVSVGQFRPEKDHLLQVRAFARARALVLIGSVRNAD-DAARALHS-LAAELDVADVDIRTDVAFPDLLGASTVGLHTMWNEHFGIAVVEYMAAGLVTLAHGTGGPLMDIVG-PRGFLATSDEFADHLP--EVAAAGRASV-MRFSDDVFDAAF Treme1 MLLGQLVAMSVATLLESMIGFWHPCNAGGGGERVLWSIIAYLLVYSGDTSKEEMLDKVQERMSIR-LSLAFIPLPLISDSYWKRFTLLGQSIGSVILAWEALMWGDIFFDTMGYGFTYPFV-RLIIAIGAYTHYPTVSVDMVKRV--RVKLVYYAIFTVLYSVSLLYAEVIMTNSSWTQAHITSLLVVFPPCDVTGLLK-LGHIVSLAQFRPEKDHAKQLYALNVLFDLTLMGGCRNTE-DEQRGLKA-LAMKLGIEDVEFVVNAPYPEVLGQASIGLNTMQDEHFGINVVEFMAAGLIPVVHASAGPMMDIVV-STGFHATDESFASSLSADRMRRVARDLARDKFSQEKFESSF Trire2 AVAPLLL--LL-ILVNLMVGFFHPCNAGGGGERVLWAAIRATFVYTGDLAKDAVLKRIKTRFNIQ-LHIQFLDLSWVLASRWPVFTLLGQSFGSIILAWDAFLVPDIFIDTMGFAFALSFS-KLLVPTGAYVHYPTISTDMLESLDPTVKKAYWRLFAQLYSVVGSSIDVVMTNSTWTQGHVKSLWVVYPPVAVSEFEKEVEVLVYIAQFRPEKNHQLVIESFANFVKLVLIGSVRDDS-DSKRKLRL-LANELGVKDVQFHINASWAEITRKASVGVNGMWNEHFGIGVVEYQAAGLIAVVHDSGGPKLDIVT-DTGFHGSTAEFAASLA--DMRLRARKSA-KRFSEEVFAERW Umbra1 LFISA-TFTFTTIILSTILGFFHPCNAGGGGERVLWTAIRDIVVYTGDARKEQILAKIKSNFDIS-INIVFVYLQLVEDNRYPRLTLLGQSIGSLFLGYEALVIPDVYFDTMGYAFTYPLV-YLLIKIAAYVHYPTISSDMLQKVQDQGKQVYYRSFAKIYGYCGNFADIVMVNSTWTKGHIESLWIVYPPCDTERFSE-LAIIASLAQFRPEKDHMLQLQSFAKLLELVLIGSSRNEG-DENRSLRL-AAKELDIEDVIFEINAPFPKLVSRAKVGLHTMWNEHFGIGVVEYMAAGMIPVAHKSGGPLMDIVT-ETGFLADNDEFAADLSPEEIATNARASVCDKFSELVFGDGI Ustma22 TLYGVLVPLLLPLLLASIIGFFHPCNAGGGGERVLYEAVQLHVIYTGDASKTEILEKASSRFGIT-LDIIMVALTMVQDSTWKRFTLLGQSYGSVWLALEALLIPDVYIDTMGYAFSYPVA-RLLMPIGAYVHYPIVSTDMLHRVACRLKLYYYRLLARLYSWALKRADVIVANGSWTRAHLEQLTRVFPPCDTEEMAQ-FGVVVSLAQFRPEKDHAMQLHILKSLLTLILMGSSRNAD-DQQRNLRS-LSTSLGLDAVEFVVNAPFSHILSTASIGLSTMKDEHFGINVVEFMASALITLSHKSAGPWLDIAC-PVGYHAESDEFAALVDPQQMRSAARLRAQSVFSRHAFIHAW Walse1 -MLAITIIISLII-----IAFFHPCNAGGGGERVLWTAIYGIFIYTGD-SKETLLSNVKNKMSIE-LNIEFIRLRLVDDKSWPYFTLLGQAIGSILLILEAM----VFIDTMGYAFTYPIV-RLITRIIAYTHYPTISTDMVSRVEHRGKLFYYKALIRAYTSCLKVCDVNMANSSWTANHLRKLIIVYPPCDTVALRE-FPLILCVAQFRPEKAHATQIEALKELQELILLGSARNQD-DLKRTLKA-LAKSLGVESVQFIVNASFDDLLSTASIGINTMIDEHFGINVVEYMAAGLIPLAHASAGPLLDIIV-DTGYHGRDKDFAQSLDSNKMRQRARNSVVERLSDKKFNEDF Zygro1 IILATTSIILIGLILAAAYGFFHPCNAGGGGEKVLWKAVQSTLIYTGDATPQEILHSVSKRFDYE-LDIVFIYLKFVDSKMWPHFTLLGQALGSALLTAEALCPPDVWCDTMGYPFGYGVV-HYLIPIITYTHYPVISTDMLNKLKLSVKYCYWSLFMMCYRYVGSFVTTAVTNSTWTNNHIKKIWIIYPPCSTEKLVLKHDNVVVIAQFRPEKRHELIIGSFAQFIALILIGSTRSQE-DRDYQLSSWAHDELSIPKLKFHTDCPYEQILSESTYGINAMWNEHFGIAVVEYVASGLIPLVHASAGPLLDIVV-PTGFFFKD-KYPTNLTAKEISKRGRECVLHKFSDFKFHQDW [Cluster2063.fasta_al_trimmed; alignment length = 224] Allma1 TARAVIPGHMAKGLREMRNKMR--QVDVIIEVRDARVPVSSMNPAFEDRYILLNKIDLAKRHVEVMEHDRSFLRKLIMTLMIAGMPNVGKSTLINSLRNLGNKG--K-AATTGGQPGVTRAVGTPIKIIYLLDTPGIMDP-QIRDIQSFNVALTGGIRD-HLAGLAEYLVFALR-ALVDLPMRPVLDHVARRGAL-EKAAAFMVQAFRT--------------- Ashgo11 FTP--RQGHQRKAMLRIEQLAP--QLNLLLEVRDSTAPLSTHNVLFDDRIILYTKRDVCAPTPAALHRAAD-AAALLYRLLVAGMPNVGKSTLVNRLRASGTRRA-K-VAATGAHPGVTRATSECVRIVFMHDTPGVALPARASSRRMLALALAGCVGP-AVVDQADYLLYLLN--YAANDIAALLAAVCTR------AALHWL-----HTRRAGRRARN---S Aspfu1 FIP--RLGHHKAGLKKMQNMLS--SIDYVIECRDYRVPITSINPMFERRLVVYTKRDLG----KIIKKRAD-VSSILCRVMVVGMPNVGKSTLINNLRNQGVRA--K-AVQTGGQPGITRKIGTPVKIVYVLDTPGVFMP-YVPDEKMLKLALCGCVKD-SVISLADYLLYHINPGQYENEISPLLDSFARQGLL-AKAALHLIQKWRSSISQALKRMSRK-QP Aurde31 LLP---PGHMNAFNKLLPALLA--RTDIVLELRDTRMPLTSINPTFEERIVVYGKRDLVKPFHGAMKTPRA-LKGLHLNVTVVGMPNVGKSTLLNGLRSVGIGAQPK-ALRTSALPGMTRALSTRLKLIYAFDTPGLMMP-FLGSERAVRLALIAALKE-GMYDLATYLVHRLNPAYLPMDAEEFLGALCARGML-LKAAQWFVQWWRESITQERKREEARERR Batde5 -ASEFRPSHQTKALQQLKNGIH--HIDLVVEVRDARIPLTSINHQFDERIVVYNKADLAKPLIDALKQGLH-AKKVLISMIVVGIPNVGKSSLINALRRLGVKG--K-VTAVGKIAGVTTAIQTRVKIIYLVDTPGIYDP-HVASMEGLKISLTGGTRD-RLTQIADYLLFRLN-KYPADQIDSVLKHICRTGFLLNKAARYMLDKYREVSNDEDD-------- Botbo1 PLP---PGHMAAFARALPSLLN--NTHIVLEVRDARLPLTSINPVLEERVVVYTKKDLVEPFQRALGKPQT-LKSLHINVLVVGMPNVGKSTLLNSLRWAGTNST-K-AMRTSAQPGFTRALSERLKLIYAIDSPGVMIP-FFGHERGVKLALIAGIKE-SLYDLASYLLYRLNPTYLSSDINVFLDALARRGAI-RKAANWFVRWWRESATRKKKREEKARER Botci1 FIP--RLGHHASGLSRMKTMLS--SIDLIIECRDYRVPLTSRNPLFEERVIVYTKRDLG----AIIKDKSD-IRTILSRILIVGMPNVGKSSLLNALRMAGVRG--K-AAFTGAQPGITRKIASGVKIVYLVDTPGVFVP-FVPDDSMLKLALVGSVKD-TIIALADYLLFHINGSVYKNDIVQFLDAVCRKGRL-GKAALWVIQRWRQSVSQARKKDTQRMRA Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------MKLAMCDLVLE-SHVNLADFLLFWLN-SYLEDDIQQVLALTCAAFRI-QQAAKYFIQLYRN--------------- Canalb1 FVP--RKGHHQKALSKFGHLAP--QLDMILEVRDSRAPISTTNVLFDKKLILYSKKDLS----RLLEKKRD-GKKIILRTMIIGMPNVGKSSLVNTLRYVGLKIR-K-VARTGGQPGVTRSTSEIIRLIMVYDTPGVFLP-TTKNETMLSLALVGCINE-SFIDLADYLLYVLN--YTDNNVYELLESIDQKNVL-QILANHWISKWKQSTSKHRKKDREFDMK Cangl FVP--RKGHQVKAIKKFKKLSP--GLNMLIELRDIRAPLSTRNVIFDERLVVYTKKDMTKQYFKKLSQTSD-AKQLLYRAFIAGMPNVGKSTLVNTLRRV-TKFK-K-VARTGSEAGVTRSTSEVIRLIYLIDSPGVGLPGRLTNNRMLTLSMCGAVKT-SLIEQADYLLYLMN--YPKNDIYEVLRRLAKN------VATNWVNKWRLRERQ----------- Capow AAR-FRPGHMARGMREIARNLQ--HIDYVIEVHDARVPVSGRNP-LLPSTLLLNKMDLGKIAKARLHE--A-TLRLEIHAMIVGMPNVGKSSTINALRRLLTGA--R-A-KVGPIPGITRAVMQPLHIIMLIDTPGIMAP-HIPNEVGLKLAAVGTFID-HQVGIADYILFSLN-DYVKDDINVFLSALAQH-VL-KGAAARFIKDYRELRAEEKRGFKRRR-- Catan2 --------------------------------------------------------------------------------MVIGTPNVGKSTLLNSLRSMASRK--K-AATTGGQPGVTRSLNTPIILVYVLDSPGIIDP-AQRDELIFRLALTGGIRD-HVAGLADYLVFALR-GLLSWSFDSILDFVATRGAL-DKAALFMVTAFRQ--------------- Cioin EFT-MRPRHMGKGLIKMRRVLK--NVDCIIEIHDARIPISGRNPGLQPYLLLLNKIDLVKQHVDAIFEHPS-VHRIIINIMVVGIPNVGKSSLIKALRAGNLKG--G-P-EVGRNPGHTRAVMNRVQVVYLLDTPGIFEP-HITDHVGMKLALCNTVHD-HVMGVADYLLYTLN-TYTKDCSLTLLKHISNERAV-QTAASVFLKAFRE-------NFE----- CocheC53 FIP--RLGHHKSGLQKMKSLLA--TIDLVIECRDYRVPLTSRNPLFEERVIVYTKRDLG----HVIAQRKS-VMKLLHRVMVVGMPNVGKSTLLNALRAQGIKG--K-VAATGAQPGVTRKVSSGVKIVYLLDTPGVFIP-YVPDEAMMKLALCGSVKD-TIIPLADYLLYHLNPTLYSNEIIELLSEIAKKGRL-GKTSLWLIQKWRSSFNQARKRERRRERN Coere1 --RLVRPGHMMAGLREMRDQMR--NVDLVVETRDARIPLSSINKQFEHRVVVYNKADLAATVQKEMAKDKS-VKQILLVVMIVGMPNVGKSTLINALRRIGVKG--K-AASTGAKPGVTRTVSGKIRVVYLVDTPGVMVP-HIPDIAAIKVALTGGIKD-NIADLADYLLFRLN-DYCNDDISYLLQMLGKKGAL-RRTIHFFLRTFRQSKNQQRKRAAQRQRT Conco1 LFREFRPGHMAKGLRLIQQRMN--ETDILIEVRDSRIPLSSMNPKFEERIVVFNKMDLIQKIRHGFKHDKN-VKKIIINIMVVGMPNVGKSSLINSLRRVGTKG--K-AMPTGAQPGITRSVGSTVKVIYLVDTPGVMIP-HIPNEQSLKVAVTGGVRD-HLADMSDYILYQLN-DYVEENIEELLTAVAKRGLL-HKAAAYWLKRYRMSKQQVKKKNKRLEKI Conpu1 FLP---PGHMSRFTKQLPSLLS--RTDVLLEIRDSRLPLTSINNNLEEHIVVLNKRDLVEPFRRAMARTRE-IKSLSMNVLVVGMPNVGKSTLLNSLRHQGIGRTAK-ALQTSSQPGHTRTVSSRLKLIYSYDSPGVMLP-FLGRERGVKLALIAGIKE-GLYDLVAYLLYRLNPAYLRNNADEFIDLLATRNMR-VRAAKWFVEWWRSSTTQERKLAEKKAKA Copci LLP---PGHMMKFTKQLPTFLA--RTDVVLEIRDSRLPLTSINRTLEEHLVILNKRDLVEPFKRAMAKPRD-IRTLNLNVLVIGMPNVGKSTLLNTLRHMGIGATSK-AFQTSANPGMTQALSTRLKLIYAYDSPGVMLP-YLGRERGVKLALIAGIKE-GLYDLAAYLLYRLNPAYLHADLYEFLTQLGQRGMI-KKAAVYFVRWWRESPTQVKKMMKEKMKR Croqu1 ----TRIGHMAKALREMNQRIK--DTDVVIEARDARLPLSSINPAFEHRLIVYNKKDLAQPLREAFARDKD-ISNLLLKIMVCGMPNVGKSSLLNALRRVGCKG--K-AASEAPMPGHTRSLGGMVKIVYIFDTPGIMPV-FLGRARAFKIALTAGSKD-SLFDLSAYLLHLLLLSEIFED---FLELIARRKAL-EQASQWLLKCFRASRTAIKMRRKVKSVQ CryneH991 ---------MARSLRELPPLLE--NINLVIEARDARLPLTSINPIFDERIVVYTKRALAKPLTRAFMQNPD-ISHILYSILVLGMPNVGKSSLLNALRRVGLKG--K-AFQTGALAGVTKKLTGTVRIVYVYDTPGVMMP-YLGKEKGLKLALTAGIKE-DLFEISDYLLWKLNPSYLSDHLPTLLSALSNRAAK-QKVMRWFVRAWRESASQQRKK--SQRLQ Crypa2 FLP--RLGHHNAALSRMRRVLS--NVGLVIECRDMRVPLTSWNPMLEARIIVYTHRDLIKRIIQALEK--D-TRTLLLRALVVGMPNAGKSTLLNRLRSQGRAS--R-VARTGAEPGVTRKLGTPVRIVFLLDTPGVFVP-FVSDEAMLKLALVGCVKD-GLISVADYLLYHLNPTGQANDVHEFLRGVARRGKL-VKAADWVVRRWRNSMNQARKKEQRRERN Debha1 FIP--RKGHHQKALTKFGHLAP--QIDLVLEVRDSRAPVSTKNVLFDEKIILYTKKDLS----DLIRKKGD-AQKIILRLMIIGMPNVGKSTLVNTLRNVGYKNR-K-VAKTGGQPGVTRATSEIIRLILVYDTPGVFLP-TVKDETMLALSLIGCVHT-SFIDQADYLLYLLN--YKENSIDELLYHIALKNKL-GKMATHWTSLWKQASSKHRKKDRKYDIQ Dekbr2 ------KGHQSKASTRMKQLAP--HIDFILELRDARVPVSSKNDLLQGRLVLYTKKDQS----SLMNRVSD-VKNLILRLMVVGMPNVGKSTLVNALRNLGLKRR-HGVAQVGSHAGVTRNTSEIIKIIYLYDTPGVLLP-RVDKWKMFSLSVAGIVSDVNQPDMADYILFVMN--YKQNDVYELL------------MAS------KN--------------- Dicdi ----FRPGHMVKNRRLLVDTLK--FIDIVMEVRDSRAPISTENPMLSTKFIVLNKNDLSSKIKQYFEKPKH-PFQLVLNVLICGLPNVGKSSFINSVRNASKNS--K-SAKVGALPGVTRHI-SGFVAIFIVDTPGIMIP-GNLDETTLTLALLGCITE-KIVPLSDFLLFKLN-NYLKDDINKFLKLVSKRKMLL--AAKYFIAQYREVKKDEKKKDEKKEVK Dmel LNP-FRPGHMTKGMRQIQQKLR--NVDCIVEIHDARIPLAGRNSQFFPHILVLNKVDLLKQQKSVLQQNNG-VLDILHNLMIIGVPNVGKSSVINVLRNVHLKS--A-A-RVGAEAGITRSVGERIKIVYMIDTPGILQP-SIKDEMGMKLALVGCLPD-HIVGIADYLLYWLN-DYVEDDISAVLAEYAHR-KV-KQAARKFIHFFRS-------GFR----- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------M------VYAVDTPGVMVP-RISNDDGLRLIATGAVKS-DRVDVAEFIFEQMGPEFREVDLNDVLQAVARRNIM---AAIRLANDFREGGSQAV--------- Fomme1 VLP---PGHMRQFMRNLPAYLS--RTDVVLELRDARLPLTSINSTFEEHIVVMNKRDLVEPYQRAMVSPRD-VKSLHLNVLVVGMPNVGKSTLLNALRNEGMGPTPK-ALRTSAFPGLTKALSTRLKLVYSFDSPGVMLP-FLGKERGIKLALIAGIRQ-GLYPLAEYLLYRLNPAYLSNDVYYFLDLLAQRRML-KRAAEWFVRWWRESATQLKKKEERTAKR Fusgr1 FIP--RLGHHATAQSDMIKRLN--TIHLILECRDLRLPLTTNNPILEERIVVFTKCDLT------LRKPDT-TKALLMRAMIVGMPNVGKSSLLNTLRRSGLLA--K-AAKTGGQPGITRKIGTSVRIVFVLDTPGVFVP-YVDNETMIKIALVQGIKI-GLVPLVDYLLYRLNPAFYKNSVEELLTSVAVKGKL-KAAASVFLKDWRTSMNQAKKKEARAQER Galma1 -----------------------------------------------------------------MAAERD-TR----------MPNVGKSTLLNALRNMGIGRTPK-AFQTSANPGMTQALSTRLKLVYAYDTPGVMLP-FLGRERGVKLALIAGIKE-GLYDLAAYLLYRLNPAYLHSDLEEFLTLLARRGMI-KRAAVYFVRWWRESQTQVKKMLEEKEKR Ganpr1 DDPSAKPGHMVKSIRLMRSKLK--SIDLVVEVRDARIPFSSVNPRFEDRLIVYNKSDLAEIVCNAFLRKKA-VRQILINALIVGMPNVGKSSLINSLREIGVRG--K-AAKVGPEAGVTRQIQERIRIIFLVDTPGIMDP-YITNHQAMKIALTGGTKD-RLVVVADYLLFFLNRRYLSRNAEELLPLLALRGAF-RQALNFWIRGFREKEAEQRARVKERQGT Gloin1 -----RPGHMAKGLRVMSERLS--NVDLIVEARDARIPLSSINHKFEDRIIVYNKADLAQPIIDAFKQDKN-VKKIIISVMVVGMPNVGKSSLINSMRRIGVKG--K-AAKTGALPGVTRSVVTSIKVVYLVDTPGVMIP-HLPDESSLKVALTGGIRD-HLSDMADYLLWRLN-GYVEDDINFLLPVISKRGAL-QKAAIFFIKQYRNSKNQEKNGIKKERKG Hisca1 FVP--RLGHHKAGLEKMKEMLS--SIDHVIECRDFRIPATSINPVFERRWIVYTKRDLG----ARIQQNNT-IVPIVARIMVVGMPNIGKSSLINALRNYAMKG--K-AAKTGADPGVTRRVGGGIKIVYVHDTPGVFMP-YMPDESMLKLALCGCVKH-TIVPLADYLLYQINPRVYENDIIPFLESYSAKGCF-AKAARKMVHMYRESINQAKKKLAKKERQ Klula1 FVP--RKGHQKKAIQRAQNLLP--QLNLLVELRDSRAPIATRNLIFDDRLVVYTKTDQCPAIIASLNKKKG-AKDLLYRMLIGGMPNVGKSTLVNSLRFTGYKPK-K-VAKTGDQAGVTRNTSECIRILFLYDTPGISLPAKAMSQRMLSLSLCGCVKN-NLVDQADFLLYLLN--YTHNNIDILLSGLKKQ------AAIYWTDSWRQNKREKHL-------- Lacbi2 ILP---PGHMMKFTRMLPALLT--RTDVVLEIRDSRLPLTSINRSLEFTL-------------RVVATERD-PNI--LNVLVIGMPNVGKSTLLNALRHMGIGRTPK-AFKTSVNPGMTQALSTRLKLVYAYDTPGVMLP-FLGRERGVKLALIAGIKE-GMYDLAAYLLYRLNPAYLHFDLEDFLTNLAQRGMI-TRAAVYFVRWWRESQTQVKKVFEEKLKR Lenti61 ALP---PGHMLQFQRMLPTLLN--KTDVVLELRDARLPLTSINRNFEERVVVFSKRDLVKPFQRAMAATRD-IKALSLNVLVVGMPNVGKSTLLNALRNIGIGPTPK-ALRTSAQPGMTRVLSTRLKLVYAYDSPGVMLP-FLGNERGVKLALIAGIKE-GLYDLASYLLYRLNPAYLQLDVQEFLTLLAKRCML-KRAAVWFIKWWRESATQEKKKEKQRVKQ Malgl1 -------------------MLARTPPPLVIEVRDARLPFTSINPKFERRLVVYTKRDQIGPIVRALAKKND-VQRVYVRLLVVGMPNVGKSSLLNALRFVGTKK--S-AASTHPHPGHTRKVTGTVRIVYVYDTPGIMVP-FLGSERALKLAITGCMKQ-TLFSLADYLLFRMNPAYTADDNTEFLSCVAGKGAR-QQAAEFVISQFQR----------SQDLQ Mellp23 ----HQIGHMAKAIKEIQSKLN--QIDLIIETRDARLPLSSINPKFESRLIVYNKKDLAKPLKEAFAKDQD-IKSVLFKIMVCGMPNVGKSSLLNALRRVGCKG--K-TASEAPMPGHTRSIGGMVKIVYMIDTPGIMPI-YLGQAIAFKIAITAGIKD-SLFDLSSYLLHILIPNEISED---FLKSISIRKAL-EKASQYLLKSFRDSQTAIKMRRKNKQIQ Mnele ------------------------NADQL----------------------------------------------------VSGIPNVGKSSFINLFKK---NK--N-KLRVAPEPGVTKKISNRLKIVYIYDTPGVNLP-VFDSETILKLAACGCVPS-SVTGAADYLLFWLNYAFLSNNIVEVLAYYARRNLM-RDAAQHFLIRFNR--------------- Monbr ----VRT--REAGLRRMQQLMR--SCDCILEIHDARLPMTGRNPKFDPRILLLNKADLADAPE--------------LRLLIAGIPNVGKSTLINAMRQTFARG--K-CAITGDQPGVTRAVQTSIRIVYVIDTPGIMLP-NVENDDAMKLAAIVTLAD-R----APRIVTAF-FRYVEDELHVVLPYVAQRGAL-RKHLLEVLTDCLLVNDDPKRREERMLMK Morel2 ------NRH---------ENLL--LCSFLSPVSKQHIPLSSINHKFEDRLIVYNKSDLAAAITKAFKEDVN-VKGIITMVMVVGMPNVGKSSLINSLRRIGVKG--K-AAPTGAIPGITRTVAGTIKVVYLIDTPGVMIP-HIPDVSAIKVALTGAISD-HLSDIADYLLFQLN-SYVKDDIKVFLPQVAKYGAL-KKAAQFLVKQYRLSRRQQKKKIEERKIK Mucci2 -----RPGHMARGLRLISERLN--SVDLVVEVRDARIPLSSVNPNFEPRLIVYNKFDLAAPITAAFAKDNN-IKEILVTLMVVGMPNVGKSSLINSLRRVGVKG--K-AAATGAQPGITRTVIGTVKVVYLVDTPGVMVP-HIADVRSLKVALTGGIRD-HLSDMADYLLFRLN-DYAKNNVDDLLKGVAKRGAV-VKAAKFFLKHYRTSRRQEKKKLEQRKNS Mydma ----MRPYHMVRGLQIMRAKVN--RCDCVIEIRDARVPLSCLNPDFEPRIILINKIDLAKTQRLA-KSEES-ANQLLYQVLVCGIPNVGKSSFINAARRHYMGG--K-ATRVGKLPGVTKSVLNYINIIRILDTPGISVP-HIEDFVGIKLALTGTFPD-HVIGIADFMLYFLN-KYLDDEFDEVIKSLASK----RKCSIMFVKAFRE--------------- Neucr2 FAP--RLGHHASALNKMRQTIS--NVGLIIECRDFRVPICSWNPLLESRIIVYTKHDLGKDMVKTLKKPNN-DKHLLMRAMVVGMPNSGKSTLLNRLRAKGMLP--K-AAQTGATPGVTRKIGTPVRIVFIMDTPGVFIP-YVSDEDMLRLALVGCVKD-GVIPVADYLLYHLNPKLYTNDVHEFLRAVATRGKL-RKAADWVVQAWRRSISQARKKEQRK--- Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 FVP--RLGHHRAGLTKMKSMLS--TIDYVVECRDYRAPVTSINPMFERRLVVYTKRDLG----RKLQSRQD-VSQIICRVLVVGMPNVGKSTLINNLRNSGTKA--K-ALKTGQQPGITRKVATQVKIVYVLDTPGVFMP-YVPDENMLKLALCGCVKD-NVISLADYLLYHINPTVYKNYVVPLIESFARQGLL-AKAALLFIQRWRQSMTQALRRTTRKNKP Phybl2 -----RPGHMAKGLRMISEKLN--SVDLIVEVRDARIPLSSVNPNFEPRLIVYNKHDLADIITKAFARDMN-IRAILVTLMIVGMPNVGKSSLINSLRRVGVKG--K-AAQTGAQPGVTRTLVGTVKVVYLIDTPGVMVP-HIADVRSLKVALTGGIRD-HLSDMADYLLYRLN-GYSTNSVDVLLESVAKRGAV-VKAAKFFLKHYRTSRRQEKKKLAARKEA Picst3 FIP--RKGHHQKALTKFGHLAP--QIDLVLEVRDSRAPLSTTNVLFDEKIVLYSKKDLS----SVLRKRKD-AQKVILRLMIIGMPNVGKSTLVNTLREVGLKRR-K-VARTGGQPGVTKNTSEIIRLILVHDTPGVFLP-TVKDETMLALGMVGCVHT-SFIDQADYLLYLLN--YAENSIDELLYHIAKYDQV-NGIASHWISLWKQARSKHRRKDREYDLK Plicr1 LLP---PGHMTRFARMLPALLS--RTDVVLELRDARLPLTSINRTLEERVVVFNKRDLVEPFTKAMSNRRD-LKALSLNVLVIGMPNVGKSTLLNALRNVGIGRTPK-ALRTSAQPGLTRSLSTRLKLVYAYDSPGVMLP-FLGRERGVKLALIAGIKE-GLYDLASYLLYRLNPAYLKADTYTFLDLLGQRGML-KRAAVWFVKWWRESGTQEKKWEEKAQKR Polpo ----FRPGHMIKATKQLKENIK--NVDVVLEIRDSRAPLSTENPLLQTHIVVFNKADMSSKIKLYYD-PRH-PYQVIINMLVIGVPNVGKSSLINSIRNACR-T--K-SAKTGALPGVTRNI-TGFRVAFLVDTPGIMIP-GVLEERALTLSLVGAISE-KIVDVADYLLFKMN-TYVTDDINRLLEHICQLGMYLTNASRYLINLFREILQQQQQKDQ----- Pucgr2 ----IQLGHMVKAIRDMKQRMN--DVDVVIETRDARLPLTSINPVFEIRLIVYNKKDLAKPLKDAFKKDED-VRQILIRIMFCGMPNVGKSSLLNALRRVGCKG--K-TASEAPMPGHTRSIGGMVRVVYAFDTPGIMVP-YLGQDRAFKMAITAGIKE-TLFDLAAYFFHLLLISRISEQ---LLSAIADRKAV-EVAAQWMLKCFRDSKTAVKMRRAKKDVQ Punst1 LLP---PGHMAKFAQNLPALLT--RTDVVLEVRDARLPLTSINGKLEERIVIFNKRDLVEPFRRAMAARAD-VKALHLNVLVVGMPNVGKSSLLNALRNIGIGPTPK-AFQTSVNPGLTQALSTRVRLIYAYDSPGVMLP-YLGKERGVKFALIAGIKE-GLYDLAAYLLYRLNPAYLTNDVLQFLEQLADRRML-KRAATWFINWWRDSKSQEKRREEKIAKR Rhior3 -------------------------------------------------MIVYNKSDLANPVRKAFARDNN-VKSILVTLMVVGMPNVGKSSLINALRRVGVKG--K-AAITGAQPGVTRTVIGTVKVVYLIDTPGVMVP-HIDDVRSLKVALTGGIRD-HLSDMADYLLYRLN-GYVDNDVNELLEGVARRGAV-VKAAKFFLKQYRTSKRQEKKKLEQRKMA Rhoto1 MAP--VIGHMHRALREITEMVQKRSLDLIIETRDARVPLTSINPAFEKRLIVYNKTDLAEPLKRALAHDEG-VRKLLIVMLVAGMPNVGKSSILNALRRTGVRG--K-AASTSSEPGHTRRLSTVIKIVYIYDTPGIMVP-YLGKEAAMKLALTGGIKE-SLFEVGEYLLWRLREGWSNEDPEEFYSALARRSAM-QRAGRWLIRAFRESANQTRKKAGKKRQS Rozal11 ---------MTKGLQ-----------------------CAAINAKCR------------SNVLDTVKK----NDRVLTKMIIVGAPNVGKSTLINNFRSMALAG--K-AVPVGKIPGITKTTGQMIKVVYMLDSPGILVP-NITNNIACKLLIVGCVKE-GMIEAAKQFIKLMN-KYFKDEEHKFLRQICNHKIF-KSAFEFVLRRFRDLTRRERKKDSRSSNE Sacce1 FTP--RKGHQVKALKTFEKLLP--QMNMIIELRDIRAPLSTRNVVFDMKLVVYTRKDLMKPYIGKLKNKTD-VRNLLYRALITGMPNVGKSTLINSLRTIFHKFK-K-VAKTGAEAGVTRATSEVIRVIYLIDTPGIGVPGRVSDNRMLGLALCGSVKN-NLVDQADYLLYLMN--YPGNDIYDVLRRLQVN------TAIEWTNKWRLSNKLKGN-------- Salro ----MRPGHMAAGLRAMQKNLR--RCDCVLEVHDARVPFIGRNPQFKPRILLLNKADLAEEKEAIMHEQAD-VRQVMLRLLIAGMPNVGKSSLVNTLRSVLAKR--K-CARTGDRPGVTRTVQQDVKIVYILDTPGVMIP-DLDNDHAMTLAML-TLRD-ELVGVADYLLFSLNFSYVDDNIDVVLAAVAKRGAL-LKAACAFLDDFRRTSSKPTKRLQREAIK Schco3 ALP---PGHMTKFTRMLPQYLS--RTHVVLEVRDCRMPLTTVNKHFDEHYVVLNKRDLMEPLRQALKKKEE-LKELRLNILVIGMPNVGKSSLLNSLRSIGIGPTAK-ALQTSNQPGRTRTLSTPLKLVYAYDAPGLMLP-FIGHERGAKFALMGGLKE-GLYDIASYLLYKLNPAYLPGSVDELLELVARKNML-KPAAELFVNWWRDSLRQQRKFADKSMRK Schpo1 FVA--RPGHMNKTLKRLKNLTS--SNDIFVEVRDARIPLTSRNYVMENRIIVYNKCDLAKHRIQNLAQPYF-AKELLVYVYFVGMPNTGKSSILNSLRNVALKS--K-SAIVGNYPGVTKRISEIVRLVYMLDTPGIMTP-SITKEDMLKLSLVGCVKE-GIVHVVDYLLFHLNPSLYSNDVDEFLQNTAYKRKL-TKVSNYVIQQYRIHNEQNKKK------- Sorma FSP--RLGHHASALNKMRQTIS--NVGLIIECRDFRVPICSWNPLLESRIVVYTKHDLGKDIVKTLRKPNN-DKNLLMRAMVVGMPNSGKSTLLNRLRAKGMLP--K-AAQTGSTPGVTRKIGTPVRIVFIMDTPGVFIP-YVSDEDMMRLALVGCVKD-GVIPVADYLLYHLNPKLYTNDVHEFLRAVATRGKL-RKAADWVVQAWRRSISQARKKEQRK--- Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 QEQQFRPTHQSRALRQLQNGIH--QIDVVVEVRDARIPLTSKNPKFDPRLIVYNKADLAKPIVDAFRRGLH-VKRILLSMVVVGLPNVGKSSLINALRRVGVKG--K-VSAVGPQAGVTQTIQTRVKIIYLVDTPGIFDP-HFTHIEGLKIALTGATKD-RLTEVADYLLFRLN-KYPADDIAKVLSHIARR----NKAAKYMIGLFRDESGVEAQGSGSR--- Sporo1 MLPPVVIGHMRRALTEIQYMIQSHSLDLIIETRDARMPLTSINPAFEKRLIVYNKADLAEPIRKALWK---------ITMLVAGMPNVGKSSILNALRRVGVKG--K-AASTSSEPGHTRRLSTVIKIVYIHDTPGIMVP-FLGREAALKLALTGGIKE-SLFELAEYLLWRLRQGWSN--------------------------------------------- Stehi1 ALP---PGHMAQFQNMLPTLLS--STDIVLELRDARLPLTSINRTFEERIVVFTKRDLVDPFCRAMEARTD-LVSLNLNVLVVGMPNVGKSTLLNALRNVGIGPTPK-AMRTSPQPGLTRALSTRLKLLYAFDTPGIMLP-FLGRERGIKLALIAGIKE-GLYDLAAYLLYRLNPAYLSTSIHELLPILAKRGML-KRAGVWFVKWWRDSVTQEKKREEDMKKR Tapde11 -----RPGHMNAALREIQQLLN--TTDLLIEVRDARIPLSSRNPQFTPRIVVYNKLDLAKRIVRAWDQGNA-VSSLLVRILVLGMPNVGKSTILNALRHVSLKS--K-AAKTGAQPGITRSTNSIFKVAYLVDTPGIMVP-FIPNETMLKLGLVHCIKD-SIVDLADYLLYILN-GYVSNDIYSLLDQIGRKGKL-RKAARLFIQDYRDSKSQVRRSVKAANPE Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 FTP--RLGHMVRSLRALPALLE--DIDLVIEARDARLALTSINPTFDEKVVVYTKRDLAVPLIKAFKSDAD-VKSILLKVLVVGMPNVGKSSLLNALRRVGMKG--K-AFRTGAEAGITRRLTGTVKIVYVYDTPGVMIP-YLGHERGLKLALTAGIKE-GLFEMVDYLLWRMNPTYLDEDPQTLLSALAQRGAL-RKSATYLIRAFRE--------------- Trire2 FVP--RLGHHQAAVSKLKTVLS--RISLVIECRDYRLPLSTHNPILEPKLIVYTKHDLG------LHKPAS-TASLLLCALIVGMPNVGKSTLLNALRSSGTTN--K-VAKTGDQAGVTRKIGTSVRVVYVLDSPGVFVP-YVEDETMMKISLVQGIKK-GLIALADYLLYKMNPQIYNNDIEEFLAAVAKRGKL-KASAARVLSEWRKSLNQGKKKEQRKEDS Umbra1 -----RPGHMAKGLRVISERLN--SVDLIVEVRDARIPLSSINPNFEPRMIVYNKFDLAAPLLDAFSRDAG-VRRILLTVMVVGMPNVGKSSLINSLRRLGVKG--K-AAPTGAQPGITRAVVGTIKVIYLIDTPGVMVP-HIPQVESLKVAVTGGIRD-HLADMVDYLLYRLN-DYVTNDCNLLLESIARRGAV-VKAAKYFLKQYRLSRRQEKKKLQARKEQ Ustma22 FTP--RAGHMARAIRSMPYLLARYPPPLVIEARDARLPLTSINPVFERRLIVYLKRDLIAAILSSMKQDSD-IKKVLVRLLILGMPNVGKSSLLNALRRVGVKG--K-AASTAPHPGHTRKLTGTVRIIYVYDTPGVMVP-FLGHERGLKLAITAGIKD-SLFDLADYLLYRLNPVYIRDDPHGRTNSIHELGSL-RKAAHFMLQHWRLSKTQAKK---QQKAS Walse1 FVP--RIGHMTKGMRMMTEQLN--TIDVIIEARDARIPLTGINYEFEERIIVYTKRDLARPLTRSLKSDRD-PRIVQLNVLITGMPNVGKSTFLNALRRVGVKG--K-AAITGSDPGVTRKLTGTVKIVYIYDTPGIMVP-FLGHEMGLKLALTSGIKP-DLIDILDYLLFKLNPPFTGNDIHTLLEDLGRRGAL-RKASQFLMNAMRN-----------QRQQ Zygro1 FIP--RKGHQLKALRRFEKLKP--QFHLVLELRDLRAPLSTRNVLLDERLVIYTKRDCFSPYLDRLAQRNA-SNHILFKVLVTGMPNVGKSTLINSMR--------K-VARTGSEAGVTRSTSESIKIVYLIDTPGVGLPARLSDNRMLALTLCGCVKR-SLVDQADYLLYLMNSTYPGNDLEVVLNRLRRH------VALRWLEEPR-RKAMRK--------- [Cluster2072.fasta_al_trimmed; alignment length = 125] Allma1 AHSAAAR-----FAHPSACSSLTAASPRLPRAPSTRTVHMLVAFTCKV--CS-TRMSKTVTRQSYYTGVVLIKCDGCAKLHLIADNKNWFQENVEEILARDQTPVDRVSLIERIAEAQREPEEPA Ashgo11 RIAGLLR-YVLGVFGGHHIGSIKVDKP-----------MMMIAFTCKK--CD-TRSSHTMSKQAYTKGTVLIQCPGCKNRHLIADHLKIFRDTVQDILAAKGESVSLTT-FEDIPEQLRPPAQDG Aspfu1 STRMLSSAFNCAQPKSRNSSSSSSSSPNLTDQIAAN-EAYQITFTCKP--CG-HRSSHRMSKHGYHRGTVLIRCPSCLNRHVIADHLNIFMDTLEDILQREGKRLTRGYVMEFWEDGTVK----- Aurde31 ---MLR-ALRLARPAAV--------PPGAASTFRRYSSRLSLTFTCTANDCN-HRSSHEFTRRAYEKGIVIVTCPSCKNRHLIADHIGWFKETVEDLVRARGERIDRGRILEYFDEPP------- Batde5 --------------------------------------RMIIGFTCKV--CK-HRSYKSMSKKAYTTGVVMIKCDGCKNTHLIADHLGWFDSTIEDIMREKGETVKR------------------ Botbo1 --ARRTTAL--------SRSYSATPPPSAP---TVTTERLSITFTCTVPDCN-SRSTHEFTKRSYERGIVIVQCPSCKNRHLIADHLGWFPDTIEDFMRAKGEKVKRGSLIEYEE---------- Botci1 ALRALSRSLSHP---------PSSPPPRAPQ--------YDLTFTCQP--CS-ARSTHRISKQGYHSGSILITCPSCKNRHVISDHLGIFGDTIEDLMKEKGMLVKKGTLLEFWSDGTSTDGDGG Caeel ----MLR----------------SATP-----------QLSLSYTCKV--CNSREGPKTFAKSSYEKGVVIVTCSGCHNHHIIADNIGWFEDNIEDHLKTRGEAVKRRDTFEIQK---------- Canalb1 -SSSVVR----------NTTSTSASNP-----------ELLLQFTCNI--CN-NRSSHNISKQAYDHGTVVVQCPSCKSRHLISDNLGFMEYNLADYLKQHHQSIETDPNFNDIPESLKQPEPKD Cangl AVRALRY-AMAGVVSGR-LGSFKVDQP-----------QIMIAFTCKK--CD-TRSSHTMSKQAYTGGTVLITCPGCKNRHLIADHLKIFSDTIEDILNAKGESVSQST-FEDIPESLKEPHPEE Capow SARALAKSLSSSAAAASRLASSTAPPPPPPSSPGATSERFLIAFTCKP--CS-HRNSKTISKHSYQKGVVLIRCDGCKQIHLIADNLNWFQTNIEEILRAKGQTVIRNPEVEINGSA-------- Catan2 ITPAIAR-----RES--STTHTTSPPP-----PASETVRFLLAFTCKV--CN-TRQSKLVTHHAYTKGVVLARCDG-----------YWFMENVEEIVQKQNEKVQKLTFLERLARAKVDPTKSA Cioin ----------------------------------------------------------------------------------------------------------------------------- CocheC53 SSPSLLR-----RPGVS-RFESNTAGPTSTTA-------YELTFTCNV--CK-TRSSHRLSKQGYHHGTVLIQCPGCKNRHLISDHLKVFSDTIEDLMREKGSLIKKGSLVEFWDDGTSTPDPPK Coere1 AHNNHSQPVVTAEETAYASNSSSKDA------------RLLIGFTCKV--CR-ERQHKTMSKNAYQNGVVLIQCDKCKNRHLIADNLGWFRDNIEDLMNGNGEEVRRLK--DSVEASQAQ----- Conco1 -MNRFTPNLRHAMPN----QENPAQG------------KMLIAFTCKV--CN-HRTHKTFSKKAYTEGVVLIQCPSCENRHLIADNLGWFRDNIEDLMNEKGEDVKFVK-DEWVPNVVGEKAEES Conpu1 --SNLCRAFRGTRRSPI------SDQPAAEASSLSVSSRYSMTFTCTAEDCDRHRSTHTFTKRAYQTGIVIIQCPGCQNRHLIADNLGWFK-NIEDILKARGEQVRRGTIVEYAD---------- Copci --SALRKALKCSRATASASSSTPAASPGTPLTQ-----RMAIAFTCTVEGCG-HRQAHMFTKRSYERGIVIVTCSGCKNRHLIADHLGWFK-TIEKLAKLQGQQVTRGSVLEYAGEAE--GAAS- Croqu1 --------------------------------------RIRIQFTCTA-TCQ-HQNTHEFSKHAYERGIVLVQCPSCKNRHLIADHLQWFTNTIVDLMRAKGEKVKRGKVLEFYDDDD------- CryneH991 -------AIRTSRSFRARWNSSAAENPQLEAPE--GSSRLQMTFTCTADDCG-HRSTHEFSKRSYQKGIVLVQCPSCKSRHLIADHLGWFK-TVEDLLAAKGEKIKKGRIIEIEEE--------- Crypa2 -MRSLTRILSTPTPSRL---SSSIPKPNTS---------YELTFTCVP--CG-TRSAHNVSKQGYHHGSVLITCPSCRNRHIISDHLNIFGNTVEELMKERGQLVKRGTLLEFWEDGSTTPAARK Debha1 SKSAVAYVAIPSVNSMR--ASIKVDDP-----------QLMIAFTCKK--CD-TRSSHTFSKQSYQKGTVLIQCPGCKNRHLIADNLKIFKDSLEEVLKAKGESVATGT-FNDIPESLREPSISD Dekbr2 ---------------------IKIDKP-----------SLLLAFTCKK--CG-TRSSHIISKQAYLTGSVLVQCPGCKNRHLIADHLNIFHDNIEDILQAKGQNVSQNV-FEDIPEHLKPPPS-- Dicdi IKNPIIKSFSNIKPISS-EKQQQPNSESVTNAEENEFKKYYIEFTCTYTECG-FVSKKTFSKHSYHKGVVLIRCDGCKKIHTIADNLGWTGYNIEEIMAEKGETVRRYL-IEDEKKSDEPPKK-- Dmel --MSALKALLTSNS-PQ--------KPVDDADKVAT--KMQLIYTCKV--CQ-TRNMKTISKLAYQRGVVIVTCEGCSNHHLIADNLNWFTDNIEEILAEKGEKVVRLTDCEFLPKHD------- Enthi ----------------------------------------------------------------------------------------------------------------------------- Falba AGSSLLRALQASRPLTSYRSSMTHPEPKDFPAPSTVQDTQLLIYTCAARECG-HQNVRFISPEAYTSGLVIARCESCRNLHLVADNLGWFSDRLEEMLSATGQTVLRRMETELAENAA------- Fomme1 --------------------------------------RLQLTFTCTVTGCT-ERSTHGFTKRAYERGIVIVTCPKCKNRHLIADHLGWFKSTIEDIMRAKGEIVSRGRIVEYVE---------- Fusgr1 IAPAVLRSFLQT------------AKPKSGQANGESAKHYQLSFTCVP--CG-HRSHHNVSKQGYHYGSTLITCPSCRNRHVISDHLHIFGDTIEELMKKKGQLVKRGTLIEFWPEDS--PGSKG Galma1 --------------------------------------RLSLTFTCTVPNCG-ERSSHQFTKQAYQKGVVLVQCPGCKNRHLIADHLGWFK-TIEDILREKGEKIQKGVIVEYAE---------- Ganpr1 ----------------------------------------MIGFTCKV--CS-TRSYHMISKQAYAKGVVIINCPGCKKNHLIADHLGWYDSTLEDMMAAAGDEVRRVTVLELLPEDVLE----- Gloin1 -----------------------------------------------------------MSKHAYNHGVVIIQCSSCNNHHLIADHLGWFRDTIEDLMYEQGEKVMKFVVLEWCPDNI--KKSRN Hisca1 SSRRLVQANHVSSSRTRHSS--------LTDSKAA---AFQITFTCKP--CG-HRSSHRISQHGYYKGTVLISCPGCRNRHVISDHLNIFMDTLEDILSEHGQTLLKGKLVEWWEDGTVRPREQE Klula1 IIRPVTKPLFSHVRTTYNLGSMKVDKP-----------MLMIAFTCKK--CN-TRSSHTMSKQAYTKGTVLIKCPGCDNRHLIADHLKIFNDTIEDIMKAEGESVSLTT-FEDIPDSLKNPSTEK Lacbi2 --SRLFKSLVVPRP-AASSSSSPS----SSSSPTTTSSRLSMTFTCTVEGCG-ERSTHQFTKRSYERGIVLVECPGCKNRHLIADHLGWFK-TIEDILRAKGEKVRRGSLVEYYD---------- Lenti61 ---MLRQAV----PQAQSQDSTPSRPQGASGVPASPASKLSLTFTCTVEACH-TRSTHQFTKRSYEKGIVIVECPGCKNRHLIADHLGWFK-TVEDLLRAKGEKVRRGKIVEYAPE--------- Malgl1 ----------------------------------------------------------------------------------------------------------------------------- Mellp23 ---------------------------------------MKIQFTCKA-TCD-TTNNHEFSKLAYEKGIVLVECPACQNRHLIADHLSWFTNNIVDLMKSKGEKVKRGKILEYYDD--------- Mnele ----------------------------------------------------------------------------------------------------------------------------- Monbr -----------------------------------------MLFTC--NQCQ-HRQQKTFSKHSYHKGVVIVRCDGCKALHLVADNLGWFNENVEDFVAAKGGQVERRTTTGSNPSDEAPPKNNA Morel2 CRRTLTTAMLSSTPSAS--PNTDPKA------------RMLIGFTCTV--CN-HRSHKTMSKHAYQHGVVIMQCDHCKNRHLIADHLGWFKNTVEDLVKEKGETVQKLTKLEWIPKEILEKKA-- Mucci2 --------------------------------------QMLIGFTCKV--CN-ERSHHTMSKHSYTKGVVLIQCPGCKNRHLIADNLGWFKDTVEDLVKEKGEAIRKIIV--------------- Mydma FIKPLVSQFKYQ-----LSELKSFGQP-----------KLSLSYTCKV--CN-TRSTKIINKQAYDTGVVLIKCDGCSNLHLIADNLGWFYDNIEDIIKEKGETVMKIEKVQFVSKK-------- Neucr2 TLSCITRKTTTTRPV------SSSPEPQSPPSD-QQQP-YELTFTCIP--CD-HRSKHKVSKQGYHHGSVLISCPNCRNRHVISDHLKLFGDTVEDLLKEKGMMVKRGTLVEFWEDGTSTPGEGK Orpsp11 STRNSFRNLMVSSHTSG---------------------KFLIGFTCKK--CN-NRSYKFISKKSYYEGVVIIRCDKCKNLHLIADHLGWYDSTIEDYFKRQQKTIIKKNLIEFLKEEQKE----- Pench1 -MRSFTSPLNALAQSSRNSH---APRP-LTESPEAEWEAYRITFTCKP--CG-HRSAHRMSKQGYHRGTVLIQCPSCDSRHVMSDHLGVFFETLEDLLKEKGQTLTHGHTLEFWEDGSVK-RNDD Phybl2 ------------------------KD------------KIMIGFTCKV--CD-ERSQHVMSKLSYTKGVVLIQCPKCENRHLIADNLGWFRDNVEDLMKENGEEVSRVV---------------- Picst3 --------------------SFKVKDP-----------QLMIAFTCKK--CD-TRSSHTFSRQAYYKGTVAIQCPGCKNRHLIADNLKIFKDSLEDVLRAKGESVATDV-FEDIPESLKSPNSEE Plicr1 --SRLFRPLRS-TPSPSARSSSTSASPTPESTPSTSSDRLSFTMTCTATGCT-TRSSHTFTKRAYQTGVVLVQCPGCSNRHLIADHLGWFS-TIEDILRAKGEGVRRGRVIEFY----------- Polpo IN--LLKNLNNISSSSSEQQQQQIKSPEAKPAENENTTQYYIEFTCTHEECG-FRSKKTFSKHSYHKGVVIIRCDGCQKYH----HLGWTGYTIEEIMAAKGVQIQRTL-IHSDSNDNN-IGSGS Pucgr2 --TRQLRPIHSRQPSPVTHDDQQSSTPGP---------RMRIQFKCIATTCD-HLNTHEFSSQAFHHGIVLVQCPSCLNRHLIADHLQWFTSTIIDLMRAKGEAVKRGRVLEFYQ---------- Punst1 PQAQLFAALDSPSPTSSGASAECADPPQNALSPDSPGSRLQITFTCTVTDCG-TRSSHEFTKRSYERGIVIVQCPGCQNRHLIADHLGWFK-TVEDLMRAKGEQVRRGHIVEYAPES-------- Rhior3 SKISFSKRLI--SPSAL-----ESKR------------QMLIGFTCKV--CE-ERSHHVMSRLAYTKGVVLIQCPSCKNRHLIADNLGWFKDTVEDLVKEKGEAIRKVVV-EWLPEIAEEGESTQ Rhoto1 --MSLAR-----IPP--VGYNSSSSTP-----------RLRITFTCTASACG-HRSSHEFARRSYEKGVVIIQCPGCGNRHLIADHLHWFSQTIEDLMREKGEQVTWQSNIEVTEEQGVA----- Rozal11 ----------------------------------------------------------------------------------------------------------------------------- Sacce1 -------YFARCAPRVRHLGSFKVDKP-----------KMMIAFTCKK--CN-TRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDTVEQLMKANGEQVSQDV-FEDIPDSLKDPHPSQ Salro ---MLSRSVRHGNSGCATDSNWSWQQQKNKAKQANHNDTYAVVFTCNK--CG-NRGSKTFSKQAYHNGVVIVNCPGCDAKHLIADNLGWFKGNIEEMLKSKGESVRK---VEVTAQDLQLPGHDK Schco3 --SRLFRALR-STPGASSSSSSAAVPPEAPAPPAPTTTRLQITFTCTAPGCTRHRSSHTFTKRAYYSGIVLIQCPQCKNRHLIADHLGWFK-TVEDLLKARGEDVKRGTTIELV----------- Schpo1 TQKFCLRNFSNKSPNVRSDADQLQPKP-----------TYNVSFTCTV--CN-TRSNHNFSKQAYHNGTVLVQCPKCKNRHLMADHLKIFSETIEDILAKKGETFKKGYGVEFKPPQ---PAKSS Sorma TLPCIARKTTTTRPVP-TSAGSSSPEPSS-------EE-YELTFTCIP--CD-HRSKHKVSKQGYHHGSVLISCPNCRNRHVISDHLKIFGDTVEDLLKEKGMMVKKGTLVEFWEDGSVTPGDKK Sphar LFTNVLRA-SKSSPIPELKSNMSMPKANDRSGTVSVGERLQIQFTCGQ--CK-ERVTKDFSKHSYEKGVVIITCPGCSNRHLIADNLGWFADNIEEIMANKGQKVQRLTSTETVSKKEGK----- Spipu1 -------AFRAVRPNSH--SSTPPASP-----------RLHAVYTCKV--CS-TRQHKSMSKHAYEKGVVIIRCEGCASLHLFADHLGWFDSTIEDIMKRKGAEVRRVAILEVVPKS-------- Sporo1 -MHSTSR-----RPR-------STGTP-----------KLRIIFTCTAKPCG-HRSSHEFSKRSYEKGVVIVQCPECNNRHL----------SL------------------------------- Stehi1 --TRLFRPLRT-TPSSSHDHHHSHAYPGDVAS-STHIHTLSLTFTCTADECN-TRSTHQFSKRSYTTGIVLIECPGCKNRHLIADHLGWFQ-TVEDLVRSRGEKVKYGKMIEYSPA--------- Tapde11 -----------------------------------------------------------MTKQAYTKGTVLIQCPSCKNRHLIADNLKIFSDNIEDILREKGESIEKGNVLEF-------PDDAT Thetr ----------------------------------------------------------------------------------------------------------------------------- Treme1 -----------------------------------------MTFTCTANDCG-HRSTHEFSKRSYERGIVLVQCPQCKNRHLIADHLGWFK-TIEDLLKARGEKVVRGRLIEIEGE--------- Trire2 SASTLTR-----SPPPT---EPSTADPPTSE-------FYQLSFTCQP--CG-HRSHHNVSKQAYHHGSTLITCPGCRNRHVISDHLNIFGDTVEDLMREKGQLVKRGSLIEFWPE--EV----- Umbra1 --IRPANRAITKTPS--AEEQVDPKH------------QMLIGFTCKV--CN-ERSHHVMSKLAYTKGVILIECPGCQNRHLIADNLGWFRDTIEDLVKEKGEGIRKVIV-EWLPDIVADE---- Ustma22 IASAVARPLLTRRAYSSTDGSSTTNHKAAASIP----TRLAITFTCTVDACG-HRSSHEFSKRSYTKGIVIVQCPGCKNRHLIADNLSWFTETIEQMIEAKGGTVRRGTVIEILS---------- Walse1 --IRRFA-----RPTPT----------------NIPTDRLRISFTCTVTDCG-ERSTHEFSKNSYTKGIVIVQCPGCKNRHLIADNLGWFNQTVEDLMKAKGEKVRKGVLIEFSD---------- Zygro1 VCRRLIKSLIPSIPRHR-----KVDKP-----------MMMIAFTCKK--CN-DRSSHTMSKQAYTKGTVLIQCPSCQVRHLIADHLKIFSDTIEDILRAKGESASLTA-FEDIPESLKD----- [Cluster2074.fasta_al_trimmed; alignment length = 80] Allma1 ELAQIRAR-RMAEAAEEMRKTMLMSVLARERLARIAIVKPQNARAVEDMVLRMAQTGQLRGKVDEDQLIDLLGNDS-DDD Ashgo11 ELQALREA-RLAEE--ARAGEGVQQYMALERLARVALVRPERARAAEAYVQQLAARGVLRARISEQQIVEILDGDS-DDD Aspfu1 ELEEVGTA-SSPEKEAERRSAILNQILAADRLGRIRLVKESRAIDVENRLIMLAQTGQIRQKVTEEQLKELLNADD-DDD Aurde31 ELQAIRAA-RMAQQHEQMKRDILATVLARERLARIALVSPQRSSQIEAILVRMAQTGQLRGRVSEEGLIGLLEQSDPGS- Batde5 ELAAIRAR-RMAEDQEEMRRNMVYQILARERLARIKMVKGDKARAVEDMLIRMAQTGQIRGKVGESQLIDLLEQHS-DEE Botbo1 -------------SEDQMRRDLLATVLARERLARIALVRPQLSGQIEASLLRMAQTGQLRGRVTEEDLIGLLERDD-DD- Botci1 -------------------------------------------------------------------------------- Caeel ---------QFSQNQETAKNGMISQILAMQRLSNLAVAKPEKAQMVEAALINMARRGQLSGKMTDDGLKALMERDS-DEE Canalb1 ELNAIRQA-RLAEAQENMTITILNRVLARERLSRVKIVRPDRAQAVENYIIKLYSMGQIHQKLGEKDIVQILDGED-DDD Cangl ELQALREA-RLAEAPQERIGSSISRFLALERLSRVSLVRPDRAQAVENYLKQLVSTGQLRNKVSEKDIVQILDGED-DDD Capow ELAAIRAR-RMAE-ETEVRQSLLMQILARARLGRIASVKPEKARAVEDLLIRMAKSGQLPGMVDEPQLIKLLSQDD-DDD Catan2 ELAQIRAR-RMVRKAEEMRKTMLMSILARERLARIAIVKPANARAVEDMVIRMAQTGQLRGKVPRTT------------- Cioin GLAELRAK-RMQERQQEMVNSILSQILARARLNNLALVKPEKSKKVEQMLVQMAQRGQIVEQMNEQQLTELLGKDS-DSD CocheC53 DLEQIRRA-RLQQ--ADQRSSILSQILAADRLGRIRLVKESRATDIENRLIMLARTGQLRSKVTEEQLKEILGADD-DDD Coere1 DLGRITGQ-QFPQEMEEKQNRMLGQILAYNRLQSMKMLKREQINAVEGILLHMSANGQIRKRLSDEELKQLLKG---DED Conco1 ELNAIRAA-RLAQ--QEMTKTMLRQILAEERLNRIALVKPEKARGLEQLLIKLAQSGQLKSKVSESYLIDLLEQDD-DDD Conpu1 QL-----------AEDEMRRDMMATVLARERLSRIALVSPERSRQVETIIARMAQSGQLRGRVSEEQLIELLDQDD-DD- Copci TDAI---------AEQEMRKDVIARILARERLSRISLVSQQRAQQIEAVLIRMAQGGQLRSKVTETQLIDLLDQDD-DF- Croqu1 DLEVIRQK-RLADQQEEIRRTAVSSIMARERLARIALVRPQRAREIEDMLLRMAQGGQLRGQVSEDQLIDVLDQDD-D-- CryneH991 GL--IPSS-----QQDEMKRTMIAAMLARERLSRISLTRPQLAAQVETLLVNMGQQGQIRGQVSDEALKGLLEQDDSDSD Crypa2 ELEQIRKA-RLEQQEAEARQSVLQQILAADRLGRIRMVKEERATDIENRLIMLAQTGQLRQKVTEDQLKDLLNADE-DDD Debha1 ELNAIRSA-RLSEKKDDMKLSMLSQILARERLSRVRIVRPDRADAVEQYIIKLAATGNITRKLSENDIVEILDGDE-DDD Dekbr2 ELKAIRAA-RLQENQNDAAQMMMTQLLAKERLARVKLVKPERADAVMKYLMQLYQSGAIKRKVNEDQIVDILEKVE-DDD Dicdi EIQQ-----QLSQEANERRQGILIQILARERLSRITIVKPEKSRQIEDLIIRAAQTGQLTERVDDAKLISLLEQED-DD- Dmel DLDALRAQ-RMSQAQEEMKHSILSQVLARARLNTLKVSKPEKAQMFENMVIRMAQMGQVRGKLDDAQFVSILESDS-DDD Enthi --QQ-----QI--QQEEQRQQIIDSVLAKERLASIALVKPEKARQVGDMILMMCQRGQMTGKINEGGLISMIDQDD-LDD Falba ----------LSNAQEDARLEMIHQILARERLNRIAVVRPDKARGVEDLLVKMAQSGRLGGRVSEQQLVGMLEQDD-DDD Fomme1 ELAAIRAA-RLQQAEEQMRRDLLATVLARERLARIALVSPTRSSQMETILLRMAQTGQLRGRVGEDQLISLLEQDDEND- Fusgr1 ELDQIRKA-RLEQQQDDARQHVLNQILAADRLGRIRLVKESRAADIENRLITLAQTGQLRQKVTEAQLKELLNADD-DDL Galma1 QA-----------QDEQMRRDLLSTFLARERLSRIALVSAERSKQIEMILLRMAQSGQLRGRVSEDQLIDLLNQED-DF- Ganpr1 -------------QMEEMRRTMLTQILARERLGRLSLTKPDVARSVEDLLLNMARSGRIQAKLTEKELIGLLEQSD-DDE Gloin1 ---------------------MLSQILARERLARISMVKADKARAVEDLLIRMAQTGQLRGKVSESQLIEILEQ------ Hisca1 ELEEIRKA-RLAQQEADASQAILNQILAADRLGRIRLVKEERAADIENRLIMLARTGQLQAKVTEEQLKELLNADD-DGD Klula1 ELRAIREA-RLRESNDGQTQAILNQILAQERLSRVALVRPERVKAVEAYLLQMVRSGAIRNKLTEQDIVGILESDE-DDD Lacbi2 KL-----------QEEQMRRDLLRTVLARERLSRIALVSPDRSKEIETILLKMAQSGQLRGQVTEEQLIDLLDQDD-DF- Lenti61 ELAAIRAA-RMNQAEEQMRRDLLATILARERLARIALVSPDRAHQIEAILLRMAQTGQLRGRVSEEQLIQLLDQDD-DD- Malgl1 -------------QRDELKRQMLSQILARERLSRIALVKPQKADTISDLLLQMARSGQVRQRVTEDQLIMLLDQND-DDD Mellp23 ---------RLADQKEEMRRTAVSQIMARERLARIALVRPQKAREIEDMLLRMAQSGQLRGQVSEDQLIGVLDQ------ Mnele GLEAIRQK-RMAERQQEMKNSMLSAILARARLNTIAQVKPERAQKVEMMLINMYQRRQIVGQVGEAELIKMLEEDS-DSD Monbr ELEALRQR-RLAEEQEQAKNSMLASIMARSRLASLRAVKPENAAMVENYLIQAAQRGQLHGKVGEEDLKHILAQDS-DSD Morel2 ELAQIRAR-RMAEQMEEMRRTMLIQILARERLSRIAIVKADKARAVEDLLIRMAQGGQVRAKITEKQLIELLEQDS-DDD Mucci2 ELQAIRAR-RLAEQMEEMRRNMLYQILARERLGRIQMVKADKARAVEDLLIRMAQSNQLRSKVTEKQLIDLLGQDD-SDD Mydma ELEAIRAQ-RLAQRELEMKNAMLTQLLARARLNSIALVKPEKAKMVENMIIQMARTGQISGKLNEQSLVNILERDS-DND Neucr2 ELEKIRKA-RLEQQEAEARKAMLNQILAADRLGRIRLVKEERATDIENRLMMLAQTGQLRSKVTEEQLKELLNADD-DDD Orpsp11 ELRAIRER-RLAEQIEDMRRNMLAQVLARERISRIAIVKPEKARAVEDYILGMARSGRLVSKINESQLIDLLEQDS-DDD Pench1 ----------------EQRASILTQILAADRLGRIRLVKESRATDIENRLIMLAQSGQLRAKVTEAQLKELLGADD-DDD Phybl2 ELQAIRAR-RMAEQMEEMRRTMLFQILARERLARIQMVKADKARAVEDLLIRMAQSNQLRNKVTEQQLIDLLGQDD-SDE Picst3 ELNAIRAA-RLAEPQDEARASALSRVLARERLSRVRMVRPERAQQVEQYILRLFQTGSINRKLSEKDIVEILDGEE-EDD Plicr1 QL-----------QEEQMRRDLMATVLARERLARIALVSPERSRQIESILLRLAQSGQLRGRVSESQLIDLLEQDD-DDW Polpo ETIE-----SLQQENEEKRKHILAQILARERLSRIAMVKADKARQVEDMIINAAQTGRLQEKVDEPKLISLLEQDD-DD- Pucgr2 ELEAIRQK-RLADENEEIRRTAVSQIIARERLSRIALVRPQRARQIEDMLIRMAQSGQLRGRVTEEQLISVLDQDD-D-- Punst1 -------------AEEEMRRNLLATVLAGARCARVALANPERSRQIESILLRMAQTGQLRGRVSEEQLIELLEQDD-DD- Rhior3 ELQAIRAR-RLAEQMEEMRRNMLYQILARERC-----------------------------------------QDD-SDD Rhoto1 DLEAIRAK-RMAEMEDEMRRTMMSQILARERLSRIALVKPERAKSIEQLLMRMAQSGQIRGKVSEDQLIDVLDQDD-DDD Rozal11 -------------QMEEMRHSFLAQILARER-RKIAIVKPEKARVVEEMLIRMRQTGQIRQKVDEDQLKGLLEQSD-DED Sacce1 ELQAIREA-RLAQENSAPVGAAIANFLALERLSRVALVRRDRAQAVETYLKKLIATNNVTHKITEAEIVSILNGED-DDD Salro GEEEQQQDPRLAQQMEEMKNQMLGSIMARARLNSIAVVKPETAALVENLLIRMAQNGQIHGKVDERELKRLLGQDS-DDD Schco3 QI-----------QEEQMRRDLMATVLARERLSRISLVSPERSRQIETILVRLVQSGQIRGRISEAQLIDLLDQDD-DL- Schpo1 ELQAIRQA-RLAQVQDEMRQNLLSQILARDRLRRIALVRKDRAEAVEELLLRMAKTGQISHKISEPELIELLEKDE-D-- Sorma ELDKIRKA-RLEQQEAEARKAMLNQILAADRLGRIRLVKEERATDIENRLIMLAQTGQLRSKVTEEQLKELLNADD-DDD Sphar ---------GLPEQRQEMKSTMLSHLLARARLGRIASVKQEKGQMIENALLNMFQSGQIKPKVTEEMLMSLIDQDDKDDS Spipu1 ELQAIRAR-RMAEQMEEMRRNMLYQILARERLARIKIVKAEKARAVEDLLIRMAQTGQIRAKVNESTLIGLLEQDS-DDD Sporo1 DLEAIRAK-RMAEAEEEQRRTVMRQILARERLSRIGLVKPERARAIEQLLMRMAQSGQLRGRVSEEQLIDVLDQ------ Stehi1 ELAALRAA-RLNQREEQMRGDLLATVLARERLSRISLVSPERSRQIEGILLRMAQSGQLRGRVSENQLIDLLEQDD-DD- Tapde11 ELSRIRAA-RLAEEVLAQRHAQLSQILARDRLRRIALVKPDRAQGIEELLLRMAKSGQIRQRVTEDELVGLLTEDD-SDD Thetr ------AA-----EAMARREQMLVRIMARERLATVRLVNEARAAAAEDHFLQLAANGQLDAKVNDSRLKDVLEA---DDD Treme1 GMRAVPAP-----QMGEMKRGMIAAMLARERLSRIALTRPELAAQVEDLLIRMGQSGQIRGKVNDENLKGLLQQDESDDE Trire2 -------------------------------------------------------------------------------- Umbra1 ELQAIRAR-RLAEDMEEMRRTMLVQILARERLARINMVKADKARAVEDLLIRMAQSGQLRSKVSEKQLIDLLGQDD-SDD Ustma22 ELQAIRAA-RMAEQQEEMKRQMLSRILARERLSRIGLVKPQKARQITDLLIRMAQSGQIRGRITEDQLIGLLDQQD-DED Walse1 ELEAIRQA-RLQQGVDEGKRMDLARILARERLSRIALVKPEHADRVQDMLLKMAKSGQIRSQVTEQQLVGLLDQDS-DD- Zygro1 ELQALREA-RLSEDSRPAVGTAIAPFLALERLTRVDMVRPDRAQAVEAYLTKLISSGHVTRKISEEEIVQILHGSD-EDD [Cluster2078.fasta_al_trimmed; alignment length = 330] Allma1 GEVTRVTRATALLLRKAFARDLSATSLALLVDVQDALDRADHALDDIARPQEQFKADVPFIPKLKPHAKVHPYTHEIYPETMFSLESTPCTWVDTVAALEKMVEKLAVIAIDLEHHSYRSYFGFLCLMQVSTREDFLVDTLT--LRVDLLNTVFADPKIVKVLHGAESDVIWLQRDLGLYLVNLFDTYHATKILRFPAHSLAYLL--KHYCHVDADKKYQLAD-WRIRPLPQDMVRYARTDTHYLLYIYDKMRTELLATLRQSNETALKVHHGWFGLYTKEAFKALHQWRDEIARDEDESTKYVLPNHMLFTLALVRTYAADIALLIRQV Ashgo11 KRIVSTIRAADIDFYRSVGQELDDTSATVVDNFEDIFEKSDHAFDSIEKPQLLFKTPVPFKPLLKPHALKHPYEYEIYNDSVLPWEATEPIWVDNVESLSQMLDELKELAVDLEHHDYRSYYGIVCLMQISSRKDWLVDTIA--LRDDLLNVIFTDPTVVKVFHGAFMDMIWLQRDLGLYVVSLFDTYHASRALGFPKHSLAYLL--ETFAKFKTSKKYQLAD-WRVRPLPKPLRDYARSDTHFLLSIYDDLRNALVEVLNASRNVAKRRFEPWRKLMYQPLLKKLYEWRDTVARRDDESVRYVMPNQLLVSLVYVRSNARTLANLIKRT Aspfu1 SSLVQMTRTVDLNFHRTFSESLDEQRDRILDSVEDLLERADACLDEIPKPQLLFERPPPFKPLLKPHAIVNPYETEIYPESTYPFESTAATFVDTLEGVKEMLSELKEIAIDLEHHDVHSYHGLVSLMQISTRKDWVVDTLKP-WREELLNEVFADPGILKVLHGSSMDIIWLQRDLGLYVVGMFDTYHAACALNYPKRSLKFLL--HKFVNFEADKRYQMAD-WRIRPLPSGMFDYARSDTHYLLYIYDHLRNELLYVLEQSKNEALQRYEGWYDYLYRAVFKAVHQWRDEVAREEDEGVQCVFPKHILFKIAIAKDRAADLLEVIKKA Aurde31 SAVLQPTKVADLAFHRTFAQDIDQCSARVLEDAVDLLERADTCIDQIHKPQLQFKPPVSWRPALKAHAKRHPYRYEIYADHMFSFEAIPFTLVTTPHEFAQMLSKLREMAVDLEHHSYRTYAGFLCLMQISTREDWVVDLLA--VREEVLAEVFADENIVKVFHGAESDIVWLQQDFSLYIVNLFDTYHASKVLEFPKHSLASLL--EAYTDFTPDKRYQLAD-WRIRPIPAEMLLYARSDTHFLLHIYDKLRELLLEVLRRSEETALRTYVGWEILAKKAVYKAVHEWRDTVARTTDESTRYVMGNSSLFKLAIVRKRGKDLLNVISRA Batde5 SSLARLTKASDVMFLRSIANSIDATSNALLEDVIDLLEKTDVYLDTNHRPQLGFQDKIPFIPRIKPHAKIHPYRSEIYPVVYFSLESTPLTWIDTPDKLETLCSILEEFAVDLEHHDFRSYQGFTCLMQISTREDFLVDTLI--LRNSLLNTSFANPQIVKVFHGAEMDIQWLQRDFGVYVVDLFDTYHASHALELEGHSLAFLL--KYYCDVVTDKRYQLAD-WRIRPLPKEMVHYARMDTHYLLYIFDRMRNELLVTLERSGLTSLNTYQGWRSLLNRAVFKAIHEWRDRIARKEDESLRFVLPNHMLQTLSLVRLYSKELAHLIFQT Botbo1 KSLIGLTKQAELAFQRTFGQGVDRCSERVLEDVVDLLENTDKCLDELPKPQLRFSRPVCARPRLKYHARVHPYRFEIPPSSLFSFESTPFTYVTTPAQLATLLAALKEIAVDLEHHSYRSYYGFVCLVQISTRQDWIVDTLV--LREELLGEVFADPQIVKVFHGAESDIVWLQQDFNLYIVNLFDTYHASKVLDFPKHSLAALL--SLYCDFAADKRYQLAD-WRIRPLPEEMLFYARSDTHYLLKVYDHLRHALLEVLSRSAQTALRVHEGWDVLVRKAVVRAVHAWRDRVAREADESPRYVLPNHYIFQLALVRERGRELLDVIKEA Botci1 AALVSTVKTADLGFHRSVGSALDEQNARLLDDVDNLLEKTDTCLDELVKPQLAFEVKPPWLPLLKPHAKVHPYETEIYPSAMYPVESTSATFVDTYEGVLEMLEELKEIAVDLEHHDTRSYVGLVSLMQVSTRKDWIVDTLKP-WRQQLLNEVFADPNIIKVFHGAYMDIVWLQRDLGLYVVGLFDTHYACRRLGFAGGSLAFLL--KKYIDFDADKKYQLAD-WRIRPLPEEMFFYARADTHFLLYIFDNLRNELLIVLQKSKETSLLRYEGWFSLIYKSVFKAVHAWRDQIARKDDDSINFVMSNSVVVNLASVKSRTGELLEVIKAA Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 PKLMNTIRAADVNFYKTLGQQIDDQSQRLLENVTGIFDKIDSTFVQIEKPQLKFKVPIPFKPKLKPHALVQPYEYEIYPDAILDWSTTKAIWVDTVEELQKMVQELKEIAVDLEHHDYRSYYGIVCLMQISNRQDWIIDTLA--LRDDLLNEVFADPDIVKVFHGAFMDIIWLQRDLGLYVVSLFDTFHASRALGFPRFSLAYLL--EVYAHFKTSKQYQLAD-WRIRPLSPPMLAYARSDTHFLLFIYDQLKNKLIQVLYDSRQVAKRRFEPWGSIVSQPVVEVLYKWRDLMAKKQDESVRYIMPNQLLVSLAAVRINAKELANLIEKT Cangl KKVMETVRASDVEFHKSVANSLEKSMKSMAENLEELFEKADRSLDIISKPQLNFKTPVPFKPLLKPNALKQPYEYEIYNNDILSWVDTNAIWVDNINSLQDMMQELKEIAVDLEHHDFRSYYGLVCLMQISTRQDYIVDTIA--LRDDLLNEVFTNPLITKVFHGAFMDIIWLQRDLGLYIVSLFDTFHASKALGLPKHSLAYLL--EKYANFKTSKKYQLAD-WRRRPLSKAMMAYARADTHFLLNIFDQMRNGLIGVLRESRNVALRRFEPWRTLMYQPLIRELYEWRDMMARRDDESPRYVMPNQLLVSLVHVRRNSKTLANLIKKK Capow QSLVAATRASDFEFYMSFRERMNGLRGRLQDALFDTLERVDNTLDAIARPQLTFADRVPFVPLVAPATLAHPYERELPAETQLTDEETPFTWIDSEEELIDFARRLSEFAIDLEHHSYRSLQGFVCLMQVSTREDVVIDTLA--VRSSMLREVFANPNILKVFHGADMDVVWLQHDFGIYTINMFDTGQAARVLELGSYSLAHLL--RYFCNVTADKKYQLAD-WRIRPIPAEMLQYAREDTHYLLYIYDRLRNELVVAYAKSRDVCLKTYESHMQLFLKQVFKALFAWRDRMGREEDESTGYVLPNHMLFHIALVRLHVTDLVQLIKRA Catan2 TKSTLVSKATTVTLHRSFANALGSASLHLQLDVQDALDKADRALDELVRPQQLFSGDIPFVPKLKPNAQVHPYAHEIYPAAMFPIETTPYDWVDTVPALEEMIAILAVIAIDLEHHSYRSYLGLTCLMQISSPQDWVVDTLA--LRLELLNLVFTNPSIVKVLHGADSDVIWLQRDLGVYLVNLFDTYHATKVLGFPSHGYAYLL--KHYCHVETDKRFQLAD-WRVRPLPADMLKYARMDTRYLIYIYDRLRAELLAVLRASAQVALKVFAGWRNMWEKAVFKALHEWRDTVARDEDESPAYVLPNHMLFSMILVRLYAGDIARMIKDV Cioin ------------------------------------------------------------------------------------------------------MDELKEIAVDLEAHSYRSYQGITCLMQLSTRKDYIVDTIA--LRAELLNQVFANPNIIKVFHGADSDIIWLQRDFGIYVVNLFDTGQAARALGLQRHSLDYLL--THYCNVQADKKYQLAD-WRIRPLPKEMLLYAQGDTHYLLYVYDMMRLDLVKVIDKSRDICCLKYESHLVLLEKEALRLIFAWRDGLARQEDESCGYVLPNHMLLQIALLRQHVLAVHQLVVEA CocheC53 AALKPTTRSADIPFQRSAGTQLDAQNARLLEAIDALLEKADTSLDEIPKPQLQFEHVPGFRPLVKPHAKIHPYQTEIYPPSVYPFESTTATLVDTPEALATMLSELKEIAVDLEHHDNRSYIGMVSLMQISTRKDWIVDTLKP-WRRKLLNEVFADPSILKVLHGAYMDIMWLQRDLGLYIVGLFDTYHAARALGYPGASLAYLL--ERHVKFTAQKQYQLAD-WRIRPLSPELFEYARADTHFLLYIYDNMRNELIDVLEKSKETSLQRYEGWYKLISRAVFRAVHRWRDDLGRKEDESPLFIMPNHAVFSVAIIRSHAEELVGVVVEA Coere1 GSGRTSDEMEDVAVQGS-----------------SLLERIDAGLS-VARPQLGFADGVAFAWKIKPHARVHPYEYEIPAEQLFAWDNTPFDFVDTAAGLQAMLEHLQEIAVDLEHHDYRSYQGFTCLVQISTRRDYVVDALA--LRSELLNDVTADPQRVKVLHGAESDVVWLQRDFGVYLVGLFDTYHATKVLNMSHHSLAHLL--RTYCRVDVDKKYQLAD-WRLRPLPTEMMAYARGDTHYLLNIFDCLRSELLEVLRRSSQTSLRRYVGWSRLLRKAVFRALHRWRDMCAREEDESPRYVLPNHMLFAIALVRMHAADIISLIAHE Conco1 QRVQYINQTLDVSSQRVLDQQLTSISNRIYEDLMELFERVDIGLDHLNRPQVFFTDKIHFVSWVKPHAIAHPYEYEIASESVLSMDEVPLYFIETVEQLEEILPKLLELAIDLEHHDYLTYQGFTCLMQISTREDFIIDTLK--LRKELLNQAFANPQIVKVLHGADFDVIWLQRDFGLYIVGLFDTYQACKLLNTDQKSLAYLLKNKTEVQFEADKKYQLAD-WRIRPLTKEMINYARADTHYLLEIYDNMKTELLTVLDWSAEVALKKHEGWSKILKKEAFKYLHRWRDMIARQQDDSVRYVLPDHLLIKFAIVRSDATEIVNIINES Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Copci ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 AALDRLTTNADLNFHRSFNKDVEKTSERLLDDIIDLLE------DALTKPQLLFHDAPSWKPSLKPHAMVHPYYYETYPTSLFSFNETPFEFVDTPEKLHRMVEKLKEIAVDLEHHDMRSYAGFTCLIQISTRSDWVVDTLA--LRKEIFGDVFTDPTIVKVFHGADSDIIWLQRDFEIFVVNLFDTYSACVVLEMPQRSLSALL--QHYCSFEADKRYQRAD-WRIRPLPDGMLYYARSDTHFLLFIYDNLRNALLEVLERSADTALKMYEGWLAAGKKWVWRHLHDWRDRVAREMDESPFYVMPNNMLRDVSIAAQYIPEITSIIVAA Crypa2 AALVSTTRTVDLSFLRTTGDRLEEHSTHLLEDAEILLEKGDIALDEIVKPQNAFEKKVPWKPLLKPHATVHPYEIEIYPATTYPIETTSPIWVDTYEGVLEMLEELREIAVDLEHHDLRTYHGLLSLMQISTQKDWVIDTLRP-WRHKLLNEVFADPKILKVFHGAFMDIIWLQRDLGLYIVGLFDTYHASVALNYPQRSLAYLL--KTFVDFDADKKYQMAD-WRIRPLTDEMLYYARCDTHYLLYVYDLMRNELISALRRSKETSLDRYTGWANSLQKSVYRAVHKWRDDLARQEDESPMFIMPQQVLMEIAKVQQSLDELFELVTTA Debha1 PNVVQTVRNSDINFYKSLSKKIDESAKSLLDNISSIFEKIDIAFDQMVKPQINFRNKVPFKPKIKPNELKQPYEFEIYPDSILPWLKTSAIWVDSVDVLNEMISLLSEIAIDLEHHDYRSYYGIVCLMQISSRQDWIIDTLK--LRDDLLNKVFTNPDIVKVFHGAFMDIIWLQRDLGLYIVSLFDTYHASKKLGFPKFSLAYLL--ETFANFKTSKKYQLAD-WRIRPLSPPMLAYARSDTHFLLNIYDQLRNKLIEVLYESRQVAKRRFEPFSSILLQPLIEALYNWRDALAKRDDESVRYIMSNQLLVSLSYVRQNAKDLANLIENT Dekbr2 PKLVGLVRLCDIDFYRSIKQESDDVRTKLLENDKQFFENVEIGMDAIEKPQTKFVPKVPFKPKIKPNAVINPYEYEIYPDWIFPWKSSQPGWVDNVEQLKALLSELEVIGVDLEHHDYRTYHGLTSLMQISTDKDYIVDPLSAQLRPHLLNIVFTNPDIIKVFHGAFMDMMWLQRDLGLYVVSLFDTYWAAKELTLGKYSLAFLL--EKYIHFRTSKKWQLAD-WRIRPLGPEMRNYAKADTHFLIELFGKIQAELIRVLYHSRKVSNRRFEPWLSLMRSPVVEALYKWRDNKARKEDESIRYIMSDFVLTSLAYVRKCIKDLTVLIRDV Dicdi GGLVQAAKLSDYSYYETFKLKMNSLGKRLLDDLSDMIDKVDKTID-IVRPQHKFEDPFPFLPKIKPNAMVHPYEYEIYTEQQTGLDETPFTWVETVRQLEELVEKLIEIAIDLEHHSYRTYQGFTCLMQISTREDFLIDTLL--LRSHILNQVFTNPSIVKVLHGSDSDIKWLQRDFGVYIVNMFDTGQASRILEYPSASLAFLL--KFYCAIDANKKYQLAD-WRIRKLPEEMIKYAREDTHYLLYIYDRLRNELIEVLRRSRELSLLRYESHINFAKKNVLKVLYHWREGLARDEDESVRYILPNQMMLTIVSIKQHSHQLIQEILKA Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi KYAVETARSTEMMSYKEVDTALNEIN-QTLNDIDVLLEAVE--IEEINKPQLNFTDKPEYKPKCKYHSKYHPYINEIQMDWQLSFEKTPLIYVNTLELLQEMIVSLNQFAVDVEHHSEHSYYGFVCLLQISTRSDYIIDTIT--LRDSILNDPFTNPNIEKVFHGCDFDMIWLSYNFGLYVVNCIDSGQCARALKLQHFSLKYLL--QKYCNVDADKKYQLAD-WRLRPLTKEMIEYARGDTHYLLYIIDQLRNECIEVLNKSNELCLRLFRSW------DTFKKLYLLRDKIARIEDESPEAVINMTMLSNIVFVEMHASEFILLTKQE Falba RSLRQVERLTDFGFLSAFRQAAQAANDQATDDVRDLLEWGHTVMEAISPPQQTFPDKVTFVPSLKPHSLAHPYAAEI------PMESTPRTWVDTPELLEDMRQKLLEIAVDLEHHSYRSFRGFVCLMQISTREDFLVDTLA--LRGHLLGDIFADPSVVKVLHGADSDIVWLERDFGLYIVNLFDTGQAARVLQLPHFSLAHLL--SSVVGVSADKRYQLAD-WRIRPLPREMAHYAQMDTHYLLFIWDRLRNQLLTAMARSLDVSLKRHAAFMQVAARAVARALCIWREGIARQEDESVPYILPNSHLLRLVAVRANADVLAALIHTA Fomme1 SSVLQATKLADVNFFRTFAQAIDSCSRKALEDVVDLFERADTSLDDLPKPQLKFRRRISWSPNLKYNAQVHPYRYEIYSRQMFSFENTPFTWIDSKEQLDLLLDQLREIAVDLEHHSYRSFSGFLCLMQISTREDFIIDTLA--LREELLNEIFTDPKIVKVLHGADSDVVWLQQDFNIYIVNLFDTYHASKLLDFPKHGLGALL--EMYCDFVPDKRYQLAD-WRIRPLPDEMMKYARSDTHFLLYIYDNLRNALLSALSRSEDTALRIYEGWNTLSLKTVFRAAHAWRDALARKEDESTRYVMPNHYLFQLALVRTQAASLLEVIRTA Fusgr1 KSLVSTIKTVDLSFQRTVGQQLDDRTSRILEDIEMSLEKADTALDEISKPQLQFERKPPWKPILKPHASVHPYEHEIYPKRVSPVDTTEATYVDTYEGVLEMLGELMEIAVDLEHHDFRSYVGLVSLMQISTRKDWIVDTLQP-WRHKLLNQVFTNPKIVKVFHGAYMDIIWLQRDLGLYVNGLFDTFFACGQLNYPAKSLAYLL--SKFVDFDADKKYQLAD-WRLRPLPQEMLYYARSDTHYLLYIYDRVRNELVRALEKSREQSLSRYEGWSSYIFKSVFRALWKWRDDTARKEDESTNFVLGNRDISEIALARSRFNEIWGYIKES Galma1 GSALAATRKSDIAFHRSLSQDLDAFSERVLDDVVDMLERTDTCLDELSKPQLLFEKKVPWYPTLKYNAKVHPYRYEIYPPRMFSLEETRATWVATKEDFEKMLAKLKEIAVDLEHHSYRSYSGFLCLMQISDREDWVVDLLA--IRGEILNEVFTDPEIVKVFHGAESDIVWLQQDFNIYVVNLFDTFHASKLLEFPRHGLANLL--EMYCDFVPDKRYQLAD-WRIRPLPEDMLKYARSDTHFLLYIYDNLRNALLEALARSAETSLRVYAGWDTLAKREVYRSVHGWRERAAREEDESTRFVLQNHVLFLMAVVKKRAKELLSVIKDA Ganpr1 RSLSLAARASDVPLFRAFDAGLTATASQLLDDVVDLLERADSALDELTKPQLLFPDPVHFVGKLKPNAKVHPYTHEIYPQHIFEMTKTLFTWVDTEEGLDAMMEKLREIAVDTEAHSYRSFQGFVCLVQISTREDFVVDTLA--LRGSVLNEVFTDPEVVKVFHGADSDIAWLQRDFGVYIVCLFDTYHATHALRMPHHGLAYLL--ERIIGVETDKRYQMAD-WRMRPIPAEMLKYARMDTHYLLRIYDALRVDLLTVLRRSAQTSLITYTGWRAALRREVFRHLHAWRDRVAREEDESTAFVMPAGHLVGVALVRKRALEVVEAVRMG Gloin1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRNELIVTLERSAETSLKTYKGYMRLQAKAVFKALHAWRDRIAREEDESTGYVLPNEMLIAMSLVRMNILELSRLIKDT Hisca1 TALVKTIRSADLNFLRSVSASIDEESVRLLDGVEELLEKADACLDEIPKPQLLFNSRPPFRPLLKPHAITHPYETEIYPSSVYPFETTTATFVDTLEGIHSMLAELKEIAIDLEHHDAHSYHGLVCLMQLSTRKDWIVDTLKP-WREELLNEVFSDPKILKVLHGSTMDVIWLQRDLGLYIVGLFDTYHAAVALNYPKKSLKFLL--EKFVNFQAEKKYQIAD-WRLRPLLPGMFDYARSDTHYLLYIYDHIRNDLIYVLERSKQEALQRYEGWRDMLVRAVFRAVHQWRDKIARFEDEGVQYVLSKQSLFKIALVRARASELVQVIKKA Klula1 SSLVQTVRSSDIDFYKSINASLEDTSTNILDSFVDLFEKSDHALDNIEKPQLSFKTPVPFKPLLKPHSLQHPYEYEIYNDSILDWDETEAIWVDTVEGLNKMKDELSELAIDLEHHDYRSYYGIVCLMQISDRHDWIVDTIA--LREELLNDIFTDPNVTKVLHGAFMDIIWLQRDLGLYIVGLFDTYHASRMLGFPKHSLAYLL--ERFANFKTSKKYQLAD-WRIRPLTKPMLAYARADTHFLLNIFDKLRNSLLDVLHESRKVAKRRFEPWKNIMFQLLLRRLYEWRDTIARRDDESPRYVMPNQLLVSLVHLRTNSKVIANLIKRT Lacbi2 ASALKATRSADIAFHRSFAKDVDAFSSRVLDDVVDLLERTDICLDELPKPQVKFKRKPPWYPTIKFNAKVHPYRYEIYPPYLFSLEETSAIWISTPDELQAMLAKLKEIAVDLEHHSYRSYTGFLCLMQISDRNDWIVDLLA--LRDEILNEIFTDPKIVKVLHGAESDVVWLQQDFNVYIVNLFDTFHASKLLDFPRHGLANLL--EMYCDYIPDKRYQLAD-WRIRPLPQEMLDYARSDTHFLLFIYDNLRNALLQVLTRSAETSLRVYVGWDTLAKKEVYVRVHGWRERVAREEDESTRYTMPNQYLFQLALVRRRAKELLEVIREG Lenti61 GCALKATRAADIPFHRSFAKEVDQTSARVLDDVVDLLERADIGLDELAKPQISFKRKVAWVPTLKYNAQVHPYHYEIYPARMFSFEETPFTWVSTSEEFATMLDKLREIAVDLEYHNYRSFGGFVCLMQISTREDFVVDTLA--LREELLNEVFTNPNIVKVFHGAESDIVWLQQDFNLYVVNLFDTYHASKVLDFPRHGLATLL--EMYCDFTADKRYQLAD-WRIRPLPEEMLQYARSDTHFLLFIYDNLRNALLEVLSRSEETALRIYEGWDTLARKAVYLAVHAWRDRIAREEDESSRYVLPNHYLFSLAVIRRRAKELLDTIRDA Malgl1 EALVPATRTADLDFYCSVKRALERISTDLQDHLSALLERADIYLDEIPKPQDKFSRQPPWERTFKPNARVGPYYVEIVPESAFPGSSQDFVWVDSAEKVRQLQKHLEEIAVDLEHHNQRSYQGIVCLMQISTRGDWIVDTLVDEVRESALNTAFTHPDKVLVLHGADHDILWLQRDLGLYVTNLFDTFQAARALQFGALSLAFLL--LRYTNFEADKRFQTAD-WRIRPLPREMLFYARSDTHALLYVYDCLRNELLEVFDRSKPTASKVYAGWKSLWIRRIVRRLHHWRDQVARKEDESPAFVMPPRVLIQLAFVRSRLDELVKTVKDE Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mnele PAVVQFLRVTEYDFFLSFMAFSKNQGERVLTGIDELLERVDKILDMILRPQLRWKVKPPFVPLIKPNAKVHPYQHELQRPWQFEVKDTPLTIIDQADQIPGLISKLEEIAVDLEAHSYRSYLGFTCLMQLSTREDFIVDTLT--LRTDLLNKVFTDPTILKVLHGGINDIMWLQRDLGLYIVNMFDTYHASKQLGLPRCSLSYLL--HRYCDVTADKQYQLAD-WRIRPLPDVMIKYAREDTHYLLYVYDCLRYELLSVYRNSNLDCQQTFRSYMDVYKKECLKLIYKWRDQTARSEDESTAFVLPNHMMLKIALVRLHVQELHLIVEKA Monbr SALITGTKASDHDFHMMFKERAIKLQDRLADDIHDVYERVDIACDEVQRPQLRFQVPVPFVPRLKPHASAHPYLTELVPQHQLDLEQTTCTWVGTREALVGLIERLKELAIDLEAHSYRTYQGFTCLMQLSTREDYLIDTLA--LRDDLLNVIFADPAILKVLHGADSDILWLQRDHSLYIVNMFDTGQATRVLNFPRHSLAWLL--QHYCNFKADKKYQLAD-WRVRPLSEEMLHYARCDTHFLLYIYDRLHSELLAVYQRSKELCLQRYETAEDALNRELFMALHAWRDQVARDEDESPRYVLPDHMLLELALVRVNVQLIQDIILTK Morel2 QTLVKATKAADVSFYKTFANNMKEASASTLDDMKDMLEKVDVVMDEIARPQLRFPDPVPFVRKIKPNAKVHPYEYEIYPEHMFPFDTTSAIWVETEEELKEMCKSLEEIAIDLEHHDYRSFQGFVCLMQISTRQDYIIDTLE--LRGSLLNQAFTDPKIVKIFHGADHDIIWLQRDFGIYIVNLFDTYHASKLLEFGAHSLAHLL--KLYADYDADKRYQLAD-WRIRPLPKEMLNYARSDTHFLLYVYDRMRNALLATLQRSAETSLKRHTGWRNLYSKAVFKAVHAWRDQMAREEDESIRYVLPNHMMFTLAPVRMHATDLALLIAQT Mucci2 KSLVAATAAAEWGFYRSFAKDLDQAGASSLDDVVELLEKADHCLDEVVRPQMKFKDPVPFERKIKPHALVHPYEYEIYPKSMFPYDTTSPTWVDTEEALLDMMKRLEELAIDLEHHNYRSFQGFTCLMQLSTREDFVIDTLE--LRDKLLNEYFANPEIVKVLHGADSDIIWLQRDFGLYIVNLFDTYFPTKVLDFPHHSLAYLL--KKYCNFDADKKYQLAD-WRIRPLPQEMLEYARSDTHFLLYIYDCLRNELLICLQRSNEVALQKYEGWKNMLAKAVFKALHSWRDHTAREEDESWRYVLPNHMLMALVLVRMNAQAIAYTIQQA Mydma QKTVQLTQYGNYEYFSSYSEFCLEEGSRLVIDIEEMLETIGSLLDEIQRPQLKFINKIPFVPYIKHNAI-HPYAYELPHDWQLMLDTTNLTYIDTDEGLNDLINKLKEIAVDLEHHSYRSFQGFLCLMQISTREDFIIDTLA--LREEMINEIFSDPNILKVMHGADSDIGWLQRDFGVYVVNMFDTGQAARTLHEDRFSLAYLL--SKYCNVDAQKQYQLAD-WRIRPIPKEMILYAQEDTHYLLYVYDILRNQLLSVYSKSTSICATMYQSYIATYEKECFRLLFEWRDKTAREEDESIVYTLPNHMLFQIALVKQRNTEIHLLVMLA Neucr2 AALVATTRTADLQFQRTVGGQLDNSSGRLLDDVDILLEKADTCLDEILKPQNNFEKKVPWKPLLKPHAKVHPYETEIYPEHVYPIDSTSAIWVDTYEGVLEMLEELKEIALDLEHHDFRSYTGLLSLMQISTRKDWVIDTLQP-WRHKLLNEVFANPNIVKVLHGAFMDVIWLQRDLGLYVVGLFDTYHACAVLGYPGRSLGYLL--SKFAEFEADKKYQLAD-WRIRPLPEEMFYYARSDTHYLLYIFDMIINELVQVLERSKDVALQRYEGWYNVLLKAVYKAVHQWRDNLARREDESPFFFMTQQVLADIAGLKSHLDDLFDVIQKA Orpsp11 KAVVSTTKATEYSFYKSFSKSIKKTNKNLLNDFTDLLEKADVCIDEILRPQLKFEDKIPAPLKIKPNAKVHPYKYEIYPENMFDYDQTPFTFIDTKEEFMKMIEKLNEIAVDLEHHDYRSFQGFTCLVQISTREDWVVDALA--MRSLMLNESFTNPNIVKVFHGAESDIVWLQCDFGVYIVNLFDTYHASHLLNYPKHSLAYLL--EFYVNFIADKKYQLAD-WRIRPLPKEMLKYARDDTHYLLYIYDRMRNELIVTLERSERTSLKVYHGWANIINRAVLKAVHKWRDQTAREEDESPRYVMPNHILRRIALVRMYSMDIARIIEKT Pench1 SALVQVTRTVDLNFHRTFSESLDEQSARIIDSVEDLLEKADACLDEIPKPQLLFHRKPPFKPLLKPHAIVHPYEAEIYPNSVYPFESTTATFVDTLDGVRQMLKELKEIAIDLEHHDVHSYHGLVSLMQISTRKDWVVDTLQP-WREDLLNEVFADPKILKVLHGSTMDIIWLQRDLGLYVVGMFDTFHAASALGFPKRSLKFLL--SKFVNFEADKRYQTAD-WRARPLPPAMFDYARSDTHYLLYIYDRLRNDLIYVNERSKHEALQRYEGWYDLLWRAVFKAVHQWRDEVARAEDEGWQCVFPKHMLFKLAITKERSHDLLEVIKKA Phybl2 KALVSAASASDMGFYRTFSKGIDHVGSRLLDDVVDLLERTDLCLDEVVRPQIKFKDRIPIERKIKPHAKVHPYEYEIYPEHMFPFDKTSATWVDTEEGLRKMMDTFEELAVDLEYHNYRSYLGFTCLMQISTREDFIIDTLE--LRDKMLNEYFADPNIVKILHGADSDIIWLQRDFGLYIVNLFDTYFVTKVLEFPHHSLAYLL--KKYCDFDADKKYQLAD-WRIRPVPEEMFDYARSDTHYLPYIYDCLRNELLQVLQRSAELSLHKDEGWKNALDKSVFKQLHYWRDHIAREEDESVRYVLPNHMLFALVLVRVNAQALALLIQRA Picst3 PKVMQTVRAADVNFYKSLAQKIDTSARGVLDNISSIFENIDSAFDQITKPQLSFRVPVPFKPKLKPNGLKQPYEYEIYPASILDWTSTTATWVDTVEELQKMVEELKEIAVDLEHHDYRSYYGIVCLMQISNRQDWIIDTLA--LRDDLLNTVFTNPHIVKVFHGAFMDIIWLQRDLGLYIVSLFDTYHASKLLGFPKFSLAYLL--ETFAHFKTSKKYQLAD-WRIRPLLPPMMAYARSDTHFLLSIFDQLKNKLIRVLFDSRQVAKRRFEPFSSIMVQSVVEALYNWRDRIAKIEDESVRFVMPNQLLVNLAHVRLNAKEVAELLENT Plicr1 GAALKAIKNSDLAFHRSLAKELDAFSSRVLDDVVDLLERADMSLDEIPKPQAKFKTKAPWYPRLKYNAQVHPYRYEIYPSRMFSFEETPFTWVDTPALFNLMLEKLRDIAVDLEHHSYRSFSGFLCLMQISTREDYIVDCLV--LRDELLNEIFTNPEIVKVFHGAESDIVWLQQNFNLFIVNLFDTFHASKILEFPRHGLANLL--EMYCDFTPDKRYQLAD-WRIRPLPEEMLLYARSDTHFLLYIYDNLRNALLEALSRSEETALRTYEGWDTLARKDVYRCVHGWRDQIAREEDESTRYVLPNHFLFQLAVLRRRARELLDAIKAT Polpo GNLISAIKISDHSYYSTFKNKMNDFGKRLLDEISEIIDKVDNFTDRIQRPQLKFEDPIPFLPKIKPNSMVHPYEYELFLAKQIGLDETAYTWVDRVDQLAALTEKLNEFAVDLEAHNYRSFQGFVCLMQVSTREDFIVDTLV--LRSHMLNVPFTNPKIVKVLHGSESDVKWLQRDFGIYIVNMFDTGQASRILEYPSASLAFLL--RFYCGVDANKKFQLAD-WRIRPVPEEMIKYAREDTHYLLYIYDRLRNELVEVLRRSKEICLIKYESHAEYLKKKIFRLLYNWREKVARDDDESVRYILPNSMMQLIVYIKQYGHELLQDILRS Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 TAALKAIKSSDVGFHRSYADAIDVCSGRVLEDLVDLLERADMNLDELRKPQLSFTRTVPWKPTLKYNAQVHPYHYEIYPAHLFSFAETPFTWVATPAAFALMLEKLRAIAVDLEHHSYRTFAGFVCLMQISTREDWIVDTLV--LRDELLNEVFTDPRIVKVFHGAESDIQWLQQDFNVFVVGLFDTFHASKVLHFPRHGLASLL--EMYCDFIADKRYQLAD-WRIRPLPQEMLDYARSDTHYLLYIYDHLRHALLEVLARSAQTTLRTFEGWDTLARKAVYRAVHAWRDRVAREEDESARYVLPNHYLFQIAVVRRRAKELLDIVRAA Rhior3 KSLVSATAAVDVGYFRSFAKELDQATASALDDVVRLLDKADICLDHVIRPQMKFKDPVPFERKIKPHAQVHPYTYEIYPENMFPFDNTSYIWVDTEAGLEEMMKALEEIAVDLEHHNYRSYQGFTCLMQLSTRQDFIIDTLE--LRDKLLNEYFADPTIVKVLHGADSDVIWLQRDFGLYLVNLFDTYFPTKVLEFPHHGLAYLL--KRYCNYDADKKYQLAD-WRIRPLPQEMLMYARADTHFLLYIYDCLRNELLNCLQRSNEVALQKYDGWKNMLSKAVFKAIHAWRDHTARDEDESVRYVLPNHMLFALVLVRMNAQALGLLIQKA Rhoto1 QALVPPTRAADLQFERTLARSLDTESERVLDLIRELLEQADEGVEKLEKPQKRFTARTLWKPILKVNASAHPYASELPPASFFSFTKTPFEWIGDEKALEKMIAEIRDLAIDLEHHDFRTWSGMTCLIQLSTRKDYIIDAIDPGVRENLLNEFFTDPEWIKVLHGAKSDIVWLQRDFGLYIVGLFDTYHATHVLGYAQHSLASLL--DMYTDFEPDKRYQLAD-WRIRPLPKEMLQYARSDTHYLLAIYDHLRLALHDVFNRSIPVSAITFSGFLVPLAREVLREVTRWREKVAREEDESTRYVLSLQGVLQITVVRRRKEDLAQLVRET Rozal11 KHTISLVKQSDLPFHLAIGERLEKSAQKILEHVVDILERIDATIEVISRPQLRFKDQIPFIPKLKPHALVHPYEYEILPEHAISLEETPLLMVNTEEQLLALIKDLEVIAIDLENHSYRSYQGFVCLMQISSRKDFIVDTLE--LRHFLLNVVFANPNIVKVLHGADSDIIWLQRDFGLYIVNMFDTYFASKELSCPSHSLAYLL--SHYAGIKVDKKYQLAD-WRIRPLPEEMVKYAREDTHYLLYIYDNMKNELIKVLSKSNDLTLKRYESWFNLYKKKVFQALHRWRDQLAREQDESTHYVLPNHMLFRIALVRLHANDLSLLISRV Sacce1 SRVINVVRAADVDFYKNFSKDLKSKADKLAEDISDLLEMSDHSLDKVEKPQLKFKSPIPFIPLLKPNALKHPYEYEIYSPEILSWDDSVPIWVDTSTELESMLEDLKEIAVDLEHHDYRSYYGIVCLMQISTRRDYLVDTLK--LRENLLNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLL--ENFANFKTSKKYQLAD-WRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIGVLYESRNVAKRRFEPWKILMYQVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVHVRQNAKLLANLIRDA Salro QSLVPAVKASDDHLYFSFKTKTRDLQQRLLDDMDECMERVSMFLDDIARPQLLFTDAIPFRPKLKPHAMRHPYEHEL------SIDECPATFVNTVDQLQDVLSALKEVAVDLEAHNVRSYQGFTCLMQVSTRRDFLIDTLA--LRGHLLNECLC------VLHGADSDILWLQRDHGLYIVCLFVCLFAMRVLGYPKYSLAYLL--KHLFHLSLDKRHQLSD-WRIRPLPADMCVYAQADTHYLLDAHDALKAELLSVFTRSTDICLQRYE----AMRLAIFRALHAWRDAVARREDESPRYVMEDHMLFSLALVRMNAHTIIETITNA Schco3 HLALSATRLADLAFHRTLRTDLDDLADRTHAPLTSLLEGADDTLDVAPAPTRVLPNPT------------HPYRRAIVPHHVLSFHTVPVQLIDTPEAFAALIGRLRLLALDLEHHSHHSYRGFVCLLQLTTRADYLIDALA--LRAHMLNEFTTDARIVKILHGAASDIPWLAENFGISLVTLFDTYHAARALGLPSLSLAHLL--KTYCGYEPDKRLARAD-WRVRPLPPTHLSYARSDTHFLPFIYDRLRAELCAVLQASARVCLRT--GREVLLDEAIYLALYRWRDATARAADEGVGTILPNSSLLLIAPVRLRAAEVVGAVLGA Schpo1 KGLMNSTAYCDIPFYKSFNENIKSVSSRFMEDIDNLFEKADYSIDKLTKPQLRFRVQPVWSWKLKPHSLVHPYEPEIYPPWVSSVDETEPIWVSTESQLSDMLKELQEIAVDLEHHDYRSFRGFVCLMQISNRKDWIVDTLE--LREELLNVVFTNPNIIKVFHGATMDIIWLQRDFGLYVVNLFDTYYATKVLGFEGHGLAFLL--QKYCDYDADKRYQMAD-WRIRPLPREMLKYAQSDTHYLLYIWDHLRNELISVFNSSKQISLRKYEGWRNVLTKMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAIARMYVEDIVKVVQEA Sorma AALVATTRTADLQFQRTVGSQLDNSSGRLLDDVDILLEKADTCLDEILKPQNNFERKVPWKPLLKPHAKVHPYETEIYPEHVYPIDSTSAVWIDTYEGVLEMLEELKEIALDLEHHDFRSYTGLLSLMQISTRKDWVIDTLQP-WRHKLLNEVFADPKIVKVLHGAFMDAIWLQRDLGLYLVGLFDTYHACAVLGYPGRSLGYLL--SKFAEFEADKKYQLAD-WRIRPLPEEMFYYARSDTHYLLYIYDMLVNELIQVLERSKDVALQRYEGWYNVLLKAVYKAVHQWRDNLARREDESPFFFMTQQVLADIAGLKSHLDHLFDVIQKA Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 AALTQVTKASELTFYKSFDERLTKTGDNLLEDVIDLLEKADICLDEILRPQLKFEDKIPFVRKIKPNALQHPYEYEIYPAHMFAMDQTPYTWIDTEEKLDELAALLEEIAVDTEHHDYRSFQGFVCLIQISTREDFIIDALA--VRSHLLNSSFTNPKIVKVFHGADMDIQWLQRDFGLYIVNLFDTYHASHVLEMAHHGLAFLL--KYYCSVETNKQYQLAD-WRIRPLPTEMLKYARSDTHYLLYIYDRMRNELLATLDRSQQTALKRYEGWRNGLRKAVFRAIHAWRDHIAREEDESQRYVLPNHMLYTLALVRLYASDIALLIENT Sporo1 AALIPPTRSADLSFERTLARNLDAQSAKVLDLIKDLLEHADEQIEKLPKPQLRFTTRTLWKPILKVN---HPYKLELPPSSLFSFDKTPFEWIGTREALDKMVEEIRELAIDLEHHDFRSWSGFTCLIQLSTRKDYVIDAIDPQVRDSLLNEFFTDPSWVKVLHGASSDVVWLQRDFGLYIVGLFDTYHATHVLGYSQHSLASLL--DMYTDFHADKRYQLAD-WRIRPLPKEMLHYARSDTHYLLAIYDHLRIALSEVFHRSTLVSSTVFSGFLIPLSKEVLRDLMRWRERVAREEDESPRYVMGIQGVLQTVVVRRRKEELIEVIQRT Stehi1 AAALKATKHSDVAFYKSFANNLDACSDRALDDLVDLLERADISLDQLPKPQLKFKRKPVWYPQLKYNAQVHPYRHEIYPSRMFSFAETPFTWVSTSIDFATMLDKLREIAVDLEYHSYRTFGGFVCLMQISSREDWIVDPFE--LRDEMLNEVFTDPKIVKIFHGAESDVAWLQQDFNLYIVNLFDTFHASKVLDFPRHGLASLL--EMYCDFTADKRYQLAD-WRVRPLPQEMLEYARSDTHFLLYIYDNLRNALLEVLSRSAETSLRVYEGWDTMAKKEVYRAVHAWRDRTAREEDESVRYVLANHFVFQLAVIRRRAKELLDCIRVA Tapde11 AAIRETVRAADLSFHRSFSKSLDSCLEKLLTDVNHLLESTDRSLEELSPPQLKFARKPPWKPLLKPHAKLHPYAYEIYPDFLFPVEDNEVSWVDTTTKLQAMLDTLKEIAVDLEHHDFHSFRGFVCLMQISNRQDWIVDTLA--LRNDLLNEVFTNPSILKVFHGANSDIVWLQRDFGLYIVNLFDTYHASKTLGLEGHGLAFLL--SKYVDFDADKRYQLAD-WRIRPLPKEMLYYARSDTHYLLYIYDLMRNELLSVLQASADVALRQYVGWQFLLQREILKALHQWRDQKAREIDESTRFVLPNQAIISIATMQANLKPLLHVIDLA Thetr GALAAASRKTDDYEYYAFISRTRASGRRIL-DVPDLLEKADMALDR--RPQDSFADHVPFACKLKYHALEHPYAAELYTEEMLPLEETPLVWVDTVAGLTDLISALEVVAIDLEAHSYRSFQGFVCLMQVSTRTDYLVDTLA--LRSEMFNKITADPRVVKVLHGANSDIVWLQRDFGVYVVNMFDTGQAARVLAYPSFGLAHLL--KFYCSVNTNKSYQLAD-WRIRPLPEDMAKYARMDTHYLLYIYDRLKNELVAVLARSREICGFVYE-WRRVYERAVFAALYDWRDAQARKLDESTGYVMPNALLARLALVRQHAMDIVQVV--- Treme1 STLDRLTTLADLAFHKTFGKAMDAGSLQVLEDVTDLLEDADEQLDEIPKPQLQFDPPIPWQHSLKLHSIVHPYYHETYPQSLFPMNETPYSFIDTPEQLEEMVTHLKEIAVDLEYHSTHSFAGFTCLIQISTRRDYIVDAIK--LRSELLGGVMVDPSIVKVFHGSQSDIPWLQQDFSIFVVGLFDTFHATLVLNFPAHSLASLL--KLYCNFDADKRYQLAD-WRIRPLPEEMEMYARADTHFLLYIYDKLRNALLETLERSAQTSLIMYQGWREACSRAVFKALHSWRDSLARNEDESPVWVLPNDKLVALSLALRHAADILSVIAST Trire2 KALISTIKSADLAFQRTVAEQLDDQTSRILEDVDMVLEKADRALDEVKKPQLDFEIPPPWKPLLKPHAKVHPYEPEIYPDRVFPVETTSATWVDTYEGVLEMLQELKEIAVDLEHHDFRTYIGLVSLLQISTRKDWIVDTLKP-WRHKLLNEVFADPTIVKVFHGAYMDMVWLQRDLGLYVNGLFDTFFASDALHYSSRSLAFLL--SKFVNFDADKRYQLAD-WRIRPIPEEMLFYARSDTHFLLYIYDKIRNDLVRVLEKSRELSLSRHEGWYNFVLKAVFRALWKWRDVTARTEDENPNFVLGTNNLVDIALARSRVNEIWSQIQEL Umbra1 TALTGATRAADLGYFRSFAKTLDSCSEKVLDDVMDLLEKADVGLDEIIRPQLRFKDTIPFIPKLKPHSKTHPYEYEIYPEQLFPFDDTKATWVDNEETLKEMCSKLEEIAVDLEHHDYRSFQGFVCLMQISTREDFIVDTLE--IRDKLLNSAFTDPNIVKVMHGATSDIIWLQRDFGLYVVDLFDTYHASKMLELPGHGLAYLL--KHYCDVDADKKYQMAD-WRIRPLPTEMLKYARSDTHYLLYIFDRMRRELLKVLADSEETSVRKHEGWRNLLSKAVFKAIHAWRDQTARDEDESVRYVLPNHMIFSLLLVRMHSHDIALAIQRA Ustma22 SALQPLTRNADLAFHRSLAKKLDSESDRVLADVTTLLESADTCLDEISPPQRHFTRKPIWLPHLKPNAKVNPYHHEIPPSHALPWLSTPFQWVSTKQQIEQLRDHLDEIAIDLEHHSYRTYQGIVCLMQLSTRGDWIIDTLSDDVRQHALNSSFTNPDKVKVLHGANHDVLWLQRDLGLYLVNLFDTYHATNVLMFPSHGLNYLM--ARYCNFDADKRYQLAD-WRIRPLPKEMLYYARSDTHTLLFIYDNLRHELMQVFIRSKQVATATYAGWRTVWRKRLVRALHRWRDTVAREEDESPRYILGANNLMMLAGLKKRIDELASLIMAE Walse1 KSAINLTKISDLSFQKSFSSRCEEIEDGVVDDLTGLLEDSSINIDKQRKPQLKWSSSIPWKPLLKPNAKAHPYQTEIYPAQQLDFNQTPFKWIDNEESLNYLLDRLSEIAIDLEHHDFRSYRGFVCLMQISIREDFIIDTLE--LRDQLLNDTFTNPAIVKVFHGADSDIVWLQRDFGVYIVNMFDTYHATKVLGFSQHSLASLL--IKFCGYTPDKRYQRAD-WRKRPLTNKMLEYARSDTHYLLYIYDMLRNTLIDVLQRSEQVSLKTHHGWYNLATKEVFRRLHQWRDQIARKEDESVHVIFSNHQLYDLAFVRIHLKDVAQCINSG Zygro1 PKVVGTVRAADVDFYRSVAKSLDKTSNELVEKLEDLFEKSDRSLDIILKPQVRFQRPIPFKPLLKPHALRQPYEYEIYNESILPWDGSEPVWVDNKESLDSMLQDLKEIAVDLEHHDYRSYYGIVCLMQVSTRTDYLVDTLA--LRDDLLNEVFANPLIVKVFHGAFMDIIWLQRDLGLYIVSLFDTYHASRALGFPRHSLAYLL--ETFASFKTSKKYQLAD-WRVRPLSKAMSAYARADTHFLLNIYDQLRNKLIGVLAESRNVAKRSFQGWKVLMNQILVKNLYEWRDTIARRDDESPRYVMPNQLLAYLVHVRTNAKALANLIVKS [Cluster2080.fasta_al_trimmed; alignment length = 144] Allma1 HYMGYFNVDTTDILIRIRLALYPDLYGPFWIPTTLIFALFVTSSMAYSYDFTRLSVAVSTIYLYLPLAVWGVARYVIDLWSIYGYGQTLWLPVTLLCIIVRWIMVALAFVVTVLLTGAPATKIVLFALAAHAAFALLLKFLFFN Ashgo11 TLAPYYAVTSEQLFHKTRSSLMLEIYSTVWIILSASIALYVSRGLRSHGQYQILVHVLWLFATYVPLVFKLVVQYGLELVQWYGFGCLVWIPLTPISLVAHLILAIAGGAYS-----LSRGRAVMAMAVMHLVFVLLIKLLIL- Aspfu1 YYSQFFDVDTNEVLRRCVSALYPDLYGPFWIATTVVVILFLTGTISFAYDFTLLSGAAGLVYGYIPIALWGALRWLIECWALYGYSNLVWIAVALVSWSLNWALVGVGFGWTVLSATAKTSKILLIVIVLHAGFAIAIKILFFA Aurde31 YYQGYFDVDTSTVLKRCYTTMIPDLYGPFWTLTTVIFSLFVFSGLA--YDFKLLSIAVGLVYSYVPIALWLALRYLVEAIAIFGYGQFIWIPVSLLCVIVRLVLVGVSFGLSILATAAKATRLLVIIAALHAALAICFQVIFFS Batde5 YWMQYFQVDSVDVGNRIITTIMPDFYGPFWVPTTVIFTLFATSTMAYEYDMTMLSFAGAVVYTYLPALLWGIAKYLFDMINVYGYGIAIWVPVSLLCIIIRWIIVLAAFALSLAT--ARAISMIFIVIGSQVALALVFKTQFFQ Botbo1 YYQQYFDVDTKTVLSRCYHTLLPDLYGPFWTLTTVIFALFVFSSLAYDYDFKLLSVAVGVVYAYVPVGLWGILRWLLDSVALWGYGMTVWIPVSLLCIALRWSLVGAASLLSVLASAAKSARLLVIIAALHLAVALTFKVLFFS Botci1 FYSQFFDVDTSSVLARCWAALYPDLYGPFWIATTVIFILFMGGTVSFAYDFGLLSGAAGLIYGYIPILLFLALKYLLECAALYGYSNLVWIPVALVSWSMNWVFVGVGFGLSVLSATKQTSKILLIVVVLHAGLAIAIKVLFFA Caeel ------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 FYRSFFDLDSDVFYVKLQKALNPELYGFVWITGTLIFLMFVSSTGSYSYDFSLLIKSISLFYGYVPFLLWAITTYLVKTVSIYGYTNVLWVPITIINLLLKWVFVGVFGAIT-----ESGKLYYIILAVVHLSFTVVVKISFFS Cangl YYSRYFQLSNEGLKKRIMYPR--DLYGPVWITATAVMAKFVVVTLVWEKQFVNLIHSIWLYYAHSPLLIYRGF--RYELISIYGYSNLIWVSISVILGVLEFIIFGLGLIP-VVP--EIYKVPFVV-LFLLIVFWLIYGILILI Capow ------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 YYARYFDVDTSDVINRIRWSLYPDLYGPFWVPTTLIFTLFVTSSLAYVYDFTRLTAATSTIYTY----------YVIDLVSIYGYGVALWVPIALLCIMVRWILVAVSFVITILVTG-----AVL-----HAVFALLLKFMFFN Cioin YYQELFNVNTDTVLQRIKGSMIPDMYGPFWICATLVLSIGVCGNLTYTPQFERLSIAAIMVYSYIPLLIKGVLWWVVDIICTYGYSLFVFIPVSILLLVFDWIALSIAILLSALQDDKKVAVVFTALLILHTALGVTFRLYFFS CocheC53 FYAQAFDVDTAEVLRRCVATIYPDLYGPVWIATTVVVILFLTGTINFAYDFKLLSGAAGLVYGYVPVGLWGVLKWLLECCCLYGYANLVWIAVALIAWSVNFTVVAVGLAFSVLSTTAKTSKILLVVVVLHAGFAIAIKVLFFA Coere1 YWAQYFNVDSRDVVQRTYMAVVPDLWGTFWIPTSVIFVIFVTASLSREYDFTMLTFAVFTVYTYIGTFVYGVTKYLMECLSVYGYAMAVWIPISVLCVLFRWVMVAVGFASSIVGRSGKLHKAIIPLLVVHALLVVVFKFKFFN Conco1 NYSKYFDVDTQDVTTRMLKSVNPDLYGPFWIPTTLIFLLFIVQSVR-----KELSVAAFSVYFYSPVLLWGVSKYLLEFLTFYGYSLTVWIPAILLCVVVDWLALFIACGSS-----NKMNR---------------------- Conpu1 YYTPYFDVDTSTVLARCYNTLLPDLYGPFWVLTTLILTLFMSSSLAYDYNFTLLSVAVTLVYAYIPVLLWLLLRYIIEAVSVWGYAHFVWIPVAILCVIVRWVLVGVGFALSVITQAQKATRLLIPLIAVHAGVALTFKVLFFG Copci YYQPYFDIDTKTVLQRCYMTMNPDLYGPFWTLTTLILALFLSSSLAYDYDFKLLSIAVSLVYAYLPVLLWLALRYVVEAISVWGYGQFVWIPVSILCVIVRWALVGIAFGLSILASAAKATRLLILLAAIHLGIAITFKVLFFG Croqu1 AYTQYFDVETKTVLERCWKTMYPDLYGPFWLPTTLIFILFFASSLSYDYDFSKLTLAVGLVYVYLPACMWATMRYIPEVINLYGYGLTVFVPVALLSIPLRGLVAIVAFAISVLAAAAKTARILLVVAGLHGIFTLVLWFAYLG CryneH991 FYQTYFDVDTTTVLKRVGMAMIPDMYGSFWTLTTLILTLYTTSTLT--SNLPLLSTATSAIYVYVPSLLWSVTKWIAEALGIYGYAMSIFIPLSLLCLILRWVLIGLGGISSVLAASNKFARLLIIVAVMHAVMALTIKILFFG Crypa2 FYAQFFDVDTSAVLQRCWAALFPDLYGPFWIATTVVFILFLGGTISFVYDFKLLTGAGGLIYGYVPMALYVALRYLLECWALYGYSNLIWVPVALISWSLNWVFVGVGFGMSVLSATKQTSKVLLIVLVLHLALSIAIKMLFFA Debha1 FYRKFFELDSITFFEKIKRALNPELYGFIWITGTLIFLMFVSSTGAYEYSFELLTLSISLFYGYVPLILYVLTTWLTKLISVYGYTNILWFPITAINFLLEWAIVLASGFVT--QESRETRLYMIILAIAHLLFTIIVKISFFG Dekbr2 YYRRYFDISTLDFFKSCYRSLNPDLYGPIWVTATLIFLLFFCNSFAHVNYFKIILSSINLLYGYVPTVLWTVLKFLTRFISIYAYANLSWVPAAVLSIFLKWGCILLGCVLSVFSNEEQKKHILLLLAIPHLGFALAVKVAFFG Dicdi YYRFLFNVDTKEVGLRLIRSMLPDLYGPFWVLTSLVFIVAVTSNLNWEVDIQKIVYSAITIYGYIPLILWGIFKWLLDMLCIYGYTLFIFVPASILCVIVQWIIVAIASIVSPLKEDTKRGLIICAIGALHIGLALVLKLYFFA Dmel YYQQFFNVDTYMVLERIANSMIPDLYGPFWITVTLIFSIAISGNIAWHYNFHLVSYAATSIFLYLPAVLWALFKYLLSLMCIYGYSLAIYIPVSILWVILQWLLVITAALLSVLTPASQFSLFLIVILSAHVVLAAGFLLYFFH Enthi FYARWFNVDTTDVLKRMLWGLI-DLYGPLWIPLTVVFLAFFSGSLS------------------------------------YDYKKLSIISXXXXXXXXXXXXXXXXXXX---------DLPLKL-IH--------------- Falba FYQQYFDVDTADVGSRILHALLPDLYGPFWVSTTVIFVLFAIGNLAFVPDFTTLPWAATTIYLYVPLAVWGIFRYLVRLYSLIGYGLSVFIPISIICVLVKWVCTGVLFLITVAASAARSTILLSVLAAINAGIALLFKFVFFT Fomme1 YYQRYFDVDTKTVLQRCVATLNPDLYGPFWTLTTVIFALFVFSSLAYNYNFQLLSIAVSLVYAYFPALLWGALRYLVEALSVWGYGQFVWIPVAALCLAVRWVLVGVACGLSVLATASKTPRAFVIIVILHLALALTFKVLFFS Fusgr1 FYAQFFDVDTSAVLSRCWAALFPDLYGPFWIATTVVLILFLGGTISFLYDFKLLSGAAGLIYGYIPMGLFLALRYLLECWALYGYSNLIWIPVALISSSLNWVFVGVGFGISVLSATRQVSKVLLVVVLLHAGLSLAIKILFFA Galma1 YYQPYFDIDTQTVLKRCYTTLIPDLYGPFWTLTTLIFALYLSSSLGYDYDFQLLSIAVTIVYTYLPVALWLALRYVVEAISVWGYAQFVWIPVSVLCVILRWVLVALAFGLSVLASAAKATRLLIILAAIHLGIAITFKVLFFS Ganpr1 YYKQYFDVDTDQVMKRVMASFVPELYGPFWVPTTVIFSLFVTTSVAFDYDFSLLSFAITICYCYAPLCIWAVCKYLLELVSVYGYGMSVWIPVSFLSIIFRWLLVLAACGITLAVRTAKAAAPVMGVILSNVALAAVFKFWFFG Gloin1 YYARYFDVDTTQVLERASKSLFPDLYGPFWIPTTVIFLLFVTATIASPYDFIILSFGFAAIYTYMPFIVWGALKYLLDTIGLYGYSLTIWLPISIINIIVRWALVIVGFAISIISRASKTSRLLLIVLAAHAAFALLLKFKFFS Hisca1 ---------------------------------------------------------------------------------------MVWIAVALVSWSLNWVLVGVGYGWSVLSATAKTSRVLLIVILLHVGLAIAIKILFFA Klula1 KLSPYFQVDETTLKQKLITALKLDLYSTVWITATVIMVLFLSYSGK---DFQIMINCLFLFYIYVPILAFLICKFVITAIDTYGVSNVVWVPIGFISVVIEWVLVAIGGAYS-----LQNGKVLLLMIGVHILFTLLVRWIIL- Lacbi2 YYQPYFDVDTKTVLRRCYTTLNPDLYGPFWTLTTLIFALYLSSSLGYDYDFQLLSIAVSLVYAYVPVLLWLGLRYVVEAISVWGYGQFVWIPVSVLCVILRWTLVGIALCLSILASAAKATRLIIILAALQVGIALSFKILFFS Lenti61 YYQPYFDVDTKMVLRRCYTTLLPDLYGPFWTLTTLIFALFVCSSLALEYDFGLLSTAVGLVYSYVPVLLWLALRYVVEAVAVWGYGQFVWIPVALLCVIVRWVLVGLAFLASILATAAKPVRLIIILAALHAAVALCFKVLFFS Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------ Mellp23 AYTIYFDVETKTVLERCWKTMYPDLYGPFWLPTTLIFILFFASSLSYDYDFTKLTLAVGLVYVYLPTCIWAAMRYIPEIINLYGYGLTIFIPVSLLSIPLRGFMSLIAFGVSIIKSSNKSAQILLAVVVLHGIFCLILWFGYLG Mnele FYQQYFNVDDQMVLERLMFACIPDLYGPLWVCITLIFSTAISGNMAWEYDFKKVSIAGTVVFSYVPALLSGFLWWLADILSLYGYSMSLFVPVSLLLCIVRWILVVALVSASVLEEEKQLALILTGLLALHVALILLFKVYFFT Monbr ------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 YYAKFFDVDTAQVMERCFASVIPDLYGPFWIATTVVFVLFVISSIVYKYDFTALTFAFGTIYSYVPTVIWGATKYLLDMLALYGYGLTIWIPVAVLCVLLRWGFVILGAAASVLSRAAQTSKSILIVVALHGLLALMLKYKFFA Mucci2 YYAQFFDVDTTQVIDRCVKSMYPDLYGPFWIATSVVFSVFVCSSLAHVYDFTLLSFAVVVVYMYCPALVWASTKYLLEIINYYGYGLTIWIPVSLLCIIARWAFVGVAFVVTVISRAAKTSRIILLILLAHTIFALVLKMAFYS Mydma YYQAFFDVDTYQVLSRILHSVIPDLYGPFWICSTLVFTIAICGNLSFKSDFQLVSLSACVIFSYVPAISWGYLTWFLEIVCVYGYSLAIFIPISIMWVVLRWIFVAIGVLTSALQDEKKVAFLFVLIIALHTILAVGFKLYFFK Neucr2 FYAQFFDVDTSSVLQRCWAALYPDLYGPFWIATTVVLILFLGGTISFAYDFRLLSGAAGLIYGYLPVALYLALRYLLECWALYGYSNLIWIPVALISWSLNWVFVGVGFGVSVLSATRQTSKVLLFVVALHFGLALAIKVLFFA Orpsp11 YYSKYFNVDTKDVIERIICTVIPDLYGPVWISTTVILTLFVTSCIAYNYDFSLLSFASVTVYTYIPLVIWFLCKYLIDLYCLYGYGLSLWIPAAVFAILLHTIFVLVPGIISYTKHCNKLASLIIFIFTSLIILILIFKVVFFK Pench1 YYERFFDVDTNEVFRRCVATVYPDLYGPIWIATTVVVILFLTGTISFEYDFRLLSGAAGLVYGYLPIALWGALRWLIECWALYGYSNLVWIAVALVSWSLNWALVGVGFAWSVLNATAKASKILLIVVVLHAALAIAIKVLFFA Phybl2 YYAGFFDVDTSQVIERCVKTLYPDMYGPFWLSTTVVFLVFVCSSLAHVYDFRLLSYAVFVVYTYSPVLLWGATKYLMEIINYYGYSLTVWVPVSLLCVLARWAFVSIGFALTVISRAAKTSRILLLILAAHGIFALTLKLAFYS Picst3 FYRSYFNLDTDTFLQKIQRASNPELYGFFWITGTLIFLMFVSATGSYEYSFELLSKSIFLFYGYVPLILYLGTAFLTKVISIYGYTNILWFPITAINFLLEWIIVLISGTITDGDASRQ---YMTILVIAHALFTILVKISFFG Plicr1 YYQPYFDVDTKTVLKRCYSTLLPDLYGPFWTLTTLIFTLFLSSSLAYDYDFQLLSIAVSLVYAYLPILLWLALRYVVEAVAVWGYGQFVWIPVSILCVIVRWVLVGVAFALSILASAAKAMRLIIVVAVLHAALALTFKVLFFS Polpo YYRFLFNVDTTEVAHRLLRSMIPDIYGPFWVTTTLVFIIAATANLNWEANFKTVVYSAIAIYGYIPLVLWGIFKWILDMLCIYGYALFIFIPASIICLIVQWIVVGVCTLVSPLKGDTKRGLIICGIAALHLGLALLLKLYFFA Pucgr2 AYSPYFDVETKTVLERCWRTMYPDLYGPFWLPTTLIFILFFASSLSYDYDFSKLSMAVGLVYVYLPACIWAAMRYIPEIINLYGYGLTVFIPVALLSIPLRSIMALAAFGLSVLAAAAKTGRILLIVFGLHAIFTLILWFGYLS Punst1 YYQQYFDVDTKTVLQRCYTTLLPDLYGPFWTLSTLIFCLFLSSSLAYDYDFHLLSIAVSLVYAYVPVLLWLALRYMVEAVAIWGYGQFIWIPVSILCVILRWVLVGVAFGLSILASAQKAMRLIIIIGALHAGLALTFKVLFFS Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 FYSGWFDVDTMTVLTRCYKTLIPDLYGPFWVPSTLVFSLFLTSSLWYAYDFTRLGAATSVVYTYLPVVMWAAIKYPVEVISLYGYQSTVWILVAWLTLILRLFLAFLGTLLSILSNANVSARLLIVAAVLHLIFAVALWWGFMA Rozal11 YYQKYFNVDTADVRRRIILSIVPDLYGPFWVATTVTFLLFTTGSIAYSYDFTKMSVSATTVYVYIPLFWWGMFKWYLNIVDLYGYAMSVLMPVALICIIIKWITVSVAAGLSELRKLAISATFITLTLAIHTGLLVFFKFYFF- Sacce1 YYSKYFQIDLTQFKKRLSAVL--DLYGAVWITATVVMINFTMSRGL--SQFKKLLHSIWLFYGYVPFITMQVLNRVPELISVYGYANLIWIPVCVILNIIQWAIVALGWA--ISSNNGKFSLSIIV-VALHTLFCLLFRFIIF- Salro YYQSFFDVNTADVTKRVKLGAIPDLYGPFWISTTLIFALALTGNLAWHYDFSKVTLAATAIYGYVPIGLWLGMRFAFDLLCLYGYSLTVYILAACLCGLFQWGIIMTVMGTSLLHDAARLRIVVIAAVLANAALAVGFKMYFFQ Schco3 YYQQYFDVDTKTVLRRCYATMIPDLYGPFWTLTTLIFALYLSSSLGYDYDFTLLSIAMSLVYAYVPACLWLGLRYIVEAIAVWGYSQFIWIPVSILCVIVRWVLVAVAFVLSILASAAKSLRLVVVIFILHAALALTFKVMFFS Schpo1 -----FNVETKDVVQRCIHTLIPDLYGPFWITTTVIQALFFSNSITSGYSIKKLISAASIIYGYIAVLLWGILVWLLDCLCLYGYANIVWLPVS-LATPVKYVLTGIGLLISICQQASNLCKLLLFIIVFHCLLALSLQLIFFS Sorma FYAQFFDVDTSSVLQRCWAALYPDLYGPFWIATTVVLILFLGGTISFAYDFRLLSGAAGLIYGYLPVALYLALRYLLECWALYGYANLIWIPVALISWSLNWVFVGVGFGVSVLSATRQTSKVLLFVVALHFGLALAIKVLFFA Sphar -------VN-------------------FYVKQPCVL---------------------------------------LELICLFGYSVFMFIPVSVVCVVLRWTAVVLGFGVSMIQSLQKTAYVVLGTASAQILLAVIFKMYFFE Spipu1 YYSQYFNVDTTDVGQRIVATVIPDLYGPFWIATTVIFALFATSTVAYTYDMTLLSLAVSTVYVYVPLVLWGVLKYLLELIDMYGYALAAWIPVSLLCIIVRWVLVAVAFASSIITQTKRASTLVLSIVLCHGALVLLFKFVFFR Sporo1 FYSSWFDVDTLTVLTRCYKTLLPDLYGPFWIPTTLIFSLFLTSSLIYTYDFTRLGAATTVVYMYLPVLVWAAIKYPVEIVSLYGYSSTVWILVAWLSLIARLLFVFLGTLVSILANANVSARLLVVVGFLHLVLAVVLYWSFLE Stehi1 YYQSYFDIDTKTVLSRCLTTLYPDLYGPFWTLTTLIFTLFITSSLAVDYDFALLSTAVGLVYAYVPVLLWGVLRYLVEALGVWGYGMFVWIPVSILCVIVRWILTGIAFAFSVLASTNKSTRLLIIIAALHAGIALAFKVLFFS Tapde11 YYSQFFNVSSDSVLDRLLNALFPDLYAPIWLATTVITVLYFASTVAYAYQFSTLTSAATLIYGYTPVLAWGVLRWLLETVSLYGYSNAAWVPVSFISISIRWIAVAVGFSISVVNRAAKTSQLMVVVVLLHIAFSLAIKFLFFS Thetr YYARYFDVSSVEFARRLGLAFLPDLYATMWIPATLIFTIAVTSNFAWSYNFHHMLLALSVISGYAPTVLAGLAYWPSSAYSLYGYASAPLVPAAMACIIIRWSAVGLAFLVSLISRAA--SPWWVVVVLAHAGVMVVVKMLFFE Treme1 FYQGYFDVDTQSVLKRVGMAMIPDLYGPFWTLSTLILTCYTTSTLTLPSDLPLLSTSISVIYTYLPSLLWATTRWVVDCLGLYGYSMGIFIPISLLCLILRWVLVGGGAMGSILESANKMTRLLIIVVVLHAAMALAMKVLFFS Trire2 FYAQFFDVDTSAVLSRCWAALFPDLYGPFWIATTVVLILFLGGTISFAYDFRLLSGAAGLIYGYIPVALFLALRYLLECWALYGYSNLIWIPVALISWSLNWVFVGVGFGLSVLSATRQVSKILLVVILLHAGLSLTIKILFFA Umbra1 YYTRYFDVDTKQVLQRCFHSMYPDLYGPFWVTTTVIFTTFVSSSLAYVYNFGTLSFAVFVLYSYSALLVWAATKYLLNIINMYGYSMTAWVPVSILCVMVRWILVAVAFALTIIARAAKTSRLLLIILFGHAIFAITLKLSFYS Ustma22 ------------------------------------------------------------------------------------------------------------------------------------------------ Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------ Zygro1 YYSRYFQLTTADFRKRVLGSL--DLYGPLWITATVVMSRFLGSGLF--RQSWKLVHSAWLFYAYTPFIAQKLL--IP-LVSTYGYSNVTWIAGCLLLSVIEWVIVSLIAL--LEA--GRKSLPLLVDVA----FCVAAKILLF- [Cluster2082.fasta_al_trimmed; alignment length = 201] Allma1 VVGLGLGDERDITLRGLDAVKRIYLEAYT-SILARLEQLYGKVHLAHRETVESESDTILNVAFLVVGDPFGATTHTDLILRAKVIHNASIMNAIGCAGLQLYSFGITISMVFFTETWRPDSWYDKVKTNGLHTLCLLDIKVREQSFENMARGRL-VYEPPRFMTVNQAVEQLLEIE-ETIAVGLARVGGTLQELHSLIIPA Ashgo11 LVGLGLSSHEDITVRGLNAVKRVYLEHYT-SILEELEGFYGKVVLADREMVESGCEEILDVAFLVVGDPFGATTHTDLVLRAKVVHNASVMNAVGSCGLQLYNFGQTISMVFFTDSWRPDSWYDKVLENGLHTLVLLDIKVKEQSPENLARGRL-IFEPPRYMSISQCCEQLLEVE-ETPCVAISRLGGSIHELHSLVILG Aspfu1 LVGLGLADETDITVKGLEVVKRVYLEAYT-SILEKLEAFYGRVIEADRELVETGSDEILDVAFLVVGDPFGATTHTDLVLRARVIPNASIMSGIGCTGLQLYNFGQTVSMVFFTENWKPTSYYDRVKENGLHTLVLLDIKVKEQSYENMARGRR-IFEPPRYMTVAQCASQMLETE-ESLAVGAARVGGTLKELHSLVLLG Aurde31 IIGLGLSDEHDITVRGLQIVKRVYLEAYT-SILAKLEDYYGKLIVADRDLVETGSDDILDVALLVVGDPLGATTHTDMLLRARIVHNASIMNAAGACGLQLYNFGQTVSLVFFTETWKPDSFYDRVAENGLHTLLLLDIKVKEQSEENLARGRK-IYEPPRYMSIPLAVSQLLETE-ETLAIALSRVGGTLEQLHSLVLVG Batde5 IIGLGLADEKDITVKGLEIVKRIYLEAYT-SILEKLEAFYGKIVIADREMVESEADAIFDIAFLVVGDPFGATTHTDLVVRAKSIHNASIMNAIGCCGLQLYNYGQTISIVFFTENWRPDSFYDKIKQNGLHTLCLLDIKVKEQSSENMARGRK-IYEPPRYMTVNQAVEQLLEIE-ETIAVGLARIGGTMEELHSFVIPG Botbo1 LVGLGLCDEKDITLRGLEVVKRVYLEAYT-SILDRLEEFYGRLILADRDMVETESDAILDVALLVVGDPFGATTHADILLRARIIHNASIMNAVGACGLQLYNFGQTVSIPFWTETWKPDSWLARIVENGMHTLVLLDIKVKEQNEENLARGRK-IYEPPRYMSPQTAISQIISAL-LTLAVTLSRVGGSLEELHSMVIVG Botci1 ------------------MPPRLVLPVSNFTILAKLSQWFSS---------------------LRTG----SLPHSTI--------------------------------------------------------------VKEQTMENMARGRK-IYEPPRYMTI------------ESLCVGAARVGGTLKQLHSLVLLG Caeel LIGLGLGDVEDITVKGLNIVKRVHLEAYT-SILTNLEKFYGRIIEADRTVVEQESDAILDVALLVVGDPFGATTHADLVLRAKVIHNASIMNAVGCCGLQLYNFGETVSIVMWTDEWQPESYYDKIALNGMHTLCLLDIKTKEQTVENMMRGRK-IFEPARYQKCSEAARQLLTIY-ETMVVGLARVGASMKDLHSLIIPG Canalb1 LIGLGLSYESDITVRGLETVKRVYLEAYT-SILESLEKFYGRIILADRELVETGSDDILDVAFLVVGDPFGATTHTDLVIRARTIHNASVMNAVGACGLQLYQFGQTVSLVFFTDSWKPDSFYGKIMENGLHTLLLLDIKVKEQSIENMARGRL-IYEPPRYMDIATAAQQLLEIE-STPCVAISRLGGTLQELHSLVMLG Cangl LIGLGLSYKSDITVRGLEAVKRVYLEHYT-SILEELEEFYGKVILADRELVESGSADILNVAFLVVGDPFGATTHTDLVLRAKVIHNASVMNAVGSCGLQLYNFGQTISMVFFTDSWRPDSWYDKVMENGLHTLVLLDIKVKEQSLENMARGRL-IYEPPRYMSIAQCCQQLLEIE-ETPVVGISRLGGTIKELHSLVILG Capow FIGLGLGDEKDITVRGLEAVRRVFLEMYT-SILERLEELYDKIEVADRETVESNADLILDVAFLVVGDPFGATTHTDMILRAKVIHNASIMNAIGCCGLQLYNYGQSVSICFFTETWRPDSFYDKIAFNGLHSLCLLDIKVKEPNLDAMMRGKV-VYDPPRYMTVNQAVEQLLEVS-DTIAAGLARVGGTLEELHSLVLAG Catan2 VIGLGLGDERDITLRGLDAIKRIHLEAYT-SILDRLEALYGQIQLAHRETVESESDSILNVAFLVVGDPFGATTHTDLILRAKVIHNASIMNAIGCCG-----------MVFFHENWRPDSWYDKILKNGLHTLCLLDIKVREQSWENMARGRL-VYEPPRYMTVNQAVEQMLEIE-ETIAIGVARVGGTMEELHSLIIPA Cioin LIGLGLGNPEDVTVKGLKAIKRVYLEAYT-SILSALEEFYGRIILADRDMVEQNSNELLNVVFLVVGDPFGATTHSDLVLRALVIHNASIMNAVGCCGLQLYNFGETVSIVFWTDTWKPSSFCDKINENGMHTLCLLDIKVKEQSIENLMRGKK-VYEPPRYMTSNLACQQLLEVV-ETMCVSLACVGAPLNQLHSLIITG CocheC53 LVGLGLADEKDITVKGLDIVKRVYLEAYT-AVLDVLEAFYGRVIIADREMVESSSDDILDVAFLVVGDPFGATTHTDLVLRARSIPNASILTSIGTTGLQLYNFGQTVSMVFFLDNWKPASFYDRIKENGLHTLVLLDIKVKEQSLENMARGRK-IYEPPRYMTVAQCAQQMLEIE-ESLAVGVARVGGTLEQLHSLVLLG Coere1 IVGLGLADERDITVKGLEAVRRVYLEGYT-SILQRLEEFYGKVIVAHRETVESSSDEILNVSFLVVGDPFGATTHTDLIIRARTIHNASIMNAVGATGLQLYNFGQTISIVFFTDDWRPDSFYERIKENGLHTLCLLDIKVREQTVENMMRNRQ-IFEPPRYMSVNLAAEQLLEIE-DTLAIGVSRLGGTLAQLHSLVLVG Conco1 VIGLGLSDEEDITVKGLKAVKRIYLEAYT-SILERLEKLYEKIIVADREMVESECDKILNVAFLVVGDPFGATTHSDLCIRAKCIHNASIMNAVGACGLQLYNFGQAVSIVFFTENWRPDSFYPRIQANGMHTLCLLDIKVKEQSIENMARGRK-IYEPPRYMTVNTAVEQLLEIE-ETLAIGVARIGGTLKQLHSLVLIG Conpu1 VVGLGLCDEKDITVRGLEAVKRVYLEAYT-SILERLEAFYGKLIVADRDMVETQSDDILNVSLLVVGDPFGATTHIDMVLRARVIHNASIMNAVGACGLQLYNFGQAVSLVFFTETWKPDSFYDRIKENGLHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSIPQAVSQLIEIE-ETLAIGLSRVGGTLAELHSLIIVG Copci VIGLGLCDEKDITVRGLEAVKRVYLEAYT-SILDRLEEFYGKVILADRDMVETQSDEILDVAFLVVGDPFGATTHTDIILRARVIHNASIMNAVGACGLQLYNFGQTVSLVFFTETWKPDSYYDRVKENGMHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSIPTAVSQMLDTE-STLAIALSRVGGTLKELHSIVIVG Croqu1 LIGLGLSSPKDITLAGLEAIRRVYLEAYT-SILDQLEALYGKLQLADREMVETQSDEILHVSFLVVGDPFGATTHTDLLLRCKAIHNASVLNAIGATGLSLYNYGQTVSIPFFIGNWKPRSWVDRLLDNGLHTLLLLDIKVKEQSEENLARGRK-IYEPPRFMSIPTAINQLLTSL-KTLAISVSRLGGSLSQLHSLIIIG CryneH991 VIGLGLSDEKDITVKGLEAVKRVYLESYT-SILEKLEAFYERVITATREMVELEADDILDISFLVVGDPLGATTHSDLLLRAQIIHNASILTALGSTGLQMYSFGQTLSLPFYTETWRPDSWYPRLEENGVHTLVLLDIKVREQSEENMARGRL-IYEPPRFMNPAQAFNQMLLTE-STLAISLSRVGGTLSELHSVVIVG Crypa2 LVGLGLSDETDITVKGLEIVKRVYLEAYT-SILSVLETYYGRVTIADREMVESNSDEILDVAFLVVGDPFGATTHTDLVLRARTVPNASIMSGIGAAGLQLYNFGQTVSMVFFTDNWRPASFYDRVRENGLHTLLLLDIKVKEQSLENMARGIR-IFEPPRYMTVGQCASQMLEVE-ESLAIGAARVGGTLKELHSLVLLG Debha1 LIGLGLSYESDITVRGLETIKRVYLEAYT-SILESLEAFYGRIILADRELVEGGSDKILDVAFLVVGDPFGATTHTDLIIRARAIHNASVMNAVGACGLQLYQFGQTVSLVFFTETWKPDSFYNKIMENGLHTLLLLDIKVKEQSIENMARGKL-IYEPPRYMNIETAASQLLEIE-ETPCVAISRLGGTLQELHSLVMLG Dekbr2 MIGLGLAYPEDITVRGLEAVKKVFLEGYT-SILESLEKFYGRITIAYRETVESQSDEILNVAFLVVGDVFGATTHTDLVIRARCIHNASVMNAVGACGLQLYKFGQAVSIVFFTDSWRPDSFYEKIMENGLHTLLLLDIKVREPDFKELMKGHL-TYEPPRYMSVAQCCQELLEVE-ETPCVAISRLGATLKQLHSVVMLG Dicdi IIGLGLGDEKDVTIKGFEAIKKIYLEAYT-SLLEALEKFYEKIIIADREMVESGCEEMLDVSFLVVGDPFGATTHTDLVIRAKVIHNASIMNAIGCCGLQLYSYGQTISMVFFTETTKPDSWYDRVKINGMHTLCLLDIKVKEQSIENMCRGRL-IYEPPRFMTVNQCIEQLLEIE-ETLCIGLSRVGGTMKELHSFIICG Dmel LIGLGLGDLKDITVKGLEIVKRVYLEMYT-SILEDMQEFYGRLLLADRDLVEQGADEILDVALLVVGDPFGATTHTDFILRAKVIHNASIMNAVGCCGLQLYKFGETVSIPYWDETWKPDSFYDKIKLNNMHTLCLLDIKVKEPTPESLMRKRK-EYMPPRFMTVAEAAHQLLSIV-ESLCVGLARVGGTLLELHSLIIPA Enthi IIGLGLYDEKDITVRGLEAVKLVFLEHYT-AILAKLEEFYGKVIIGDRDLVETEADQILNVALLVVGDVYGATTHSDIFVRCQVIHNASIMNAIGCSGLQLYRFGQTVSVCFWSEHWRPSSYYPKIKINNMHTLVLLDIKVKERSEENIIKGRD-IFEPPRYMTINQCIEQLLEVEKETMVVGMARVAGKMKDMHCLLIPA Falba IIGLGLSDAKDITVRGLETVRKVFLEAYT-SILEELEEFYGVVLLADRELVEQGSDEILEVAFLVVGDPFGATTHTDMVLRARVIHNASIMNAIACCGLQLYSFGQTISIPFFTKTWQPDSFYPRIKSNGLHTLALLDIKVKEQSEINLARGRK-IYEPPRFMTVRQAAEQLLLIE-ESLAIGMSRVGAPLEKLHSLVLVG Fomme1 VIGLGLYDEKDITVRGLEIVKRVYLEAYT-SILERLEEFYGRVIVADREMVELQSDEILDVSLLVVGDPFGATTHSDMLLRARVIHNASIMNAIGACGLQLYNFGQAVSLVFFTETWKPDSFYDRIKENGMHTLVLLDIKVKEQTEENLIKRRK-IYEPPRYMSIPTAVSQLLEVE-STLAIAMSRVGGTLAELHSLVIVG Fusgr1 LVGLGLSDETDITVKGLEVVKRVYLEAYT-SILSVLESYYGRITVADREMVESNSEEILDVAFLVVGDPFGATTHTDLVLRARTVPNASIMSGIGACGLQLYNFGQTVSMVFFTDTWKPASFYDRIKENGLHTLVLVDIKVKEQSLENMARGRL-VYEPPRYMTVGQCAQQMLEIE-ESLAIGAARVGGTLEELHSLVLLG Galma1 IIGLGLSDENDITLRGLQAIKRVYLEAYT-SILERLEAFYEKLILADREMVETQSDEILDVSLLVVGDPFGATTHTDIILRARVIHNASIMNAMGACGLQLYNFGQTVSLVFFTETWKPHSFYDRIKENGMHTLLLLDIKVKEQSEENLARGRK-IYEPPRYMSIPTAVSQLIETE-ETLAIALSRVGGTLRELHSLVIVG Ganpr1 LVGLGLADEKDITVKGLEAVRRVYLEAYT-SLLEKLEDFYGKITIADREAVESAADAILNVSFLVVGDPYGATTHTDLVIRAKSIHNASILNAVGVCGLQLYNYGMAVSIPFFTETWRPDSFYEKIQTNGLHTLCLLDIKVKEPTLESLARGRK-IYEPPRFMTVNQAINQLLEVE-NTIGVGLARVGGTLGELHSLIVPG Gloin1 IIGLGLSDEKDITIKGLEAIKRIYLEAYT-SILEKLEELYGKLILADREMVESQSDDILNVAFLVVGDPFGATTHADLIIRAKTIHNASIMNAVGACGLQLYNFGQTISIPFFTDNWRPDSFYDRIKENGLHTLCLLDIKVKEQSIENLARGRK-IYEFPRYMTINQAIMQLLEIE-ETLAIGIARLGGTLNQLHSLIIVG Hisca1 LVGLGLADETDITVRGLEIVKRVYLEAYT-SILEKLEAFYGRVIVADRELVETGSDDILDVAFLVVGDPFGATTHTDLVLRARTIPNASIISAIGCTGLQLYNFGQTVSMVFFTETWKPSSFYDRVKENGFHTLMLLDIKVKEQSLENMARGRK-IYEPPRYMTVAQCASQMLEIE-ESLAIGAARVGGTLKELHSLVLLG Klula1 FIGLGLSYETDITVRGLNAIKRVYLEHYT-SILEELEEFYGKVTLADRELVESGAEELLDVAFLVVGDVFGATTHTDLVLRAKVIHNASVMNAVGSCGLQLYNFGQTISMVFFTDSWRPDSWYDKIWENGLHTLVLLDIKVKEQSIENMARGRL-IYEPPRYMSIAQCCEQLLEIE-ETPCVAISRLGGTIKELHSLVILG Lacbi2 IIGLGLSDEKDITLRGLEAIKRVYLEAYT-SILRRLEDFYQKLILADRDMVETQSDEILDVSLLVVGDPFGATTHTDIILRARVVHNASIMNAVGACGLQLYNFGQTVSLVFFTDTWKPDSFYDRIKENGMHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSIHTAVSQLLETE-ATLAIALSRVGGTLQELHSLVIVG Lenti61 IIGLGLCDERDITLRGLEAVKRVYLEAYT-SILERLEAFYGKLIVADRDMVETESDEILDVSLLVVGDPYGATTHTDIVLRARIIHNASIMNAVGACGLQLYNFGQTVSLVFFTETWKPDSFYDRIKENGMHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSITQAVSQLTEVE-ETLAIALSRVGGTLTELHSLVIVG Malgl1 ----------------------------------MQELLYERITLAHRETVELEADDILNVAFLVVGDPLSATTHADLIIRARIIHNASITTALGSSGLAGYNFGQTVSIPFWTEDWQPDSWLFRIGENGLHTLCLSDIKVREQSIEDMSRGIA-RYQPPRYMLIPQLIAQLVAAA-QTLAIALCRMGGTLAELHSLVLVG Mellp23 LIGLGLSSPEDITLAGLNAIKRVYLESYT-SFLSELETFYGKIVVADRDMVETQSDKILNVSFLVVGDPFGATTHTDLLLRCKTFHNASILNAIGATGLSLYNFGQTVSVPFFDGNWKPTSWVDRLLDNGLHTLLLLDIKVKEQSVENLARGRK-IYEPARYMTIPTAIMESIVDS-KTLGISVSRVGGTLTQLHSLIIIG Mnele LIGLGLGDVTDITVKGLETVRKVFLEAYT-SLLDTLEKYYKKITIADREMVESQSELILDVAFLVVGDPLGATTHTDIILRAIVIHNASIMNAVASTGLQLYNFGDTVSICFWKENWKPTSFVDKIIKNGLHVLCLLDIRVKEIDWSKMVRGKK-VYEPPQFMSVNTAVEQILEII-KSLCVGIARLGGTLKRLHSLCIVG Monbr LIGLGLSDEKDITARGLEIVKEVFLEAYT-AILDKLEAFYGRVTVADRELVEQQCEERLDIALLVVGDPFAATTHTDLVTRCKAVHNASIMNAIGCCGLQLYNFGRTVSIVFFTEQWRPDSFYAKMKANGLHTLCLVDIKVKEQSIENLIKGRK-IFEPPRYMTVNQCAKQLLEVE-ESLAVGVARVGGTLSELHSLVVIG Morel2 VIGLGLSDERDITVKGLDAVRRIYLEAYT-SILEKLEAFYNKVTVADREMVESDSDTILNVAFLVVGDPFGATTHTDLVIRAKTIHNASIMNAIGACGLQLYNFGQTISMVWFTETWRPDSWYPRVKENGLHTLCLLDIKVKEQSLENMARGRL-IYEPPRFMTVNTCLEQMLEIE-ETLAIGCVRLGGTMEQLHSLVIIG Mucci2 VVGLGLGDEKDITVAGLEAVKRIYLEAYT-SILEKLEEYYGKVVIADREMVESDSDTILDVSFLVVGDPYGATTHTDLVIRARVIHNASIMNAIGACGLQLYNFGQTISIVFFTETWRPDSFYDRVKENGLHTLCLLDIKVKEQSIENMARGRL-IYEPPRYMTVNQAVEQLLEIE-ESLAIGCARIGGTLEELHSLVLIG Mydma LIGLGLGDAKDITIKGLEIVQKVFLEAYT-SIIEELESFYGRLTLADRNLVEQGADEILDVAFLVVGDPFGATTHTDLIIRAKVIHNASILNAVGCCGLQLYNFGETVSIVMWQDNWRPDSFYDKIIANKLHTLCLLDIKVKEQSIENMMRGKA-IFEPPRYLTANEAINQLLEVTNESFCVALARVGGTMNEIHSLIIPG Neucr2 LVGLGLSDETDITVKGLEVVKRVYLEAYT-SILATLESYYGRIVVADREMVESNSDEILDVAFCVVGDPFGATTHTDLVLRARTVPNASIMSGIGAAGLQLYNFGQTVSMVFFLDNWRPASFYDRIKENGLHTLVLLDIKVKEQSLENMARGRK-IYEPPRYMTVGTCAQQMLEIE-ESLAIGCARVGGTLKELHSLILLG Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 LVGLGLADETDITVRGLEIVKRVYLEAYT-SILEKLEAFYGRVIEADRELVETGSDDILDIVFLVVGDPFGATTHTDLVLRARVVPNASIMSGIGCTGLQLYNFGQTVSMVFFTETWKPSSYYDRVRENGLHTLVLLDIKVKEQSLENMARGRR-IFEPPRYMTVAQCAAQMLETE-ESLAVGAARVGGTLKELHSLVLLG Phybl2 IVGLGLSDETDITVKGLQAVKRIYLEAYT-SILEKLEAYYGKVVIADREMVETESDAILNVSFLVVGDPYGATTHTDLVIRARVIHNASIMNAVGACGLQLYNFGQTISIVFFTDTWRPDSFYDRIIENGLHTLCLLDIKVKEQSIENMARGRK-IYEPPRYMTVNQAVEQLLEIE-ESLAIGCARIGGSLSELHSLVLVG Picst3 LIGLGLSYESDITVRGLEVVKRVYLEAYT-SILLSLEQFYGRVILADRELVETGSDQILDIAFLVVGDPFGATTHTDLIIRARAIHNASVMNAVGACGLQLYQFGQTVSLVFFTDSWRPDSFYNKVMENGLHTLLLLDIKVKEQSIENMARGRL-IYEPPRYMDIATAASQLLEIE-ETPCVAISRLGASLKELHSLVMLG Plicr1 IIGLGLCDEKDITVRGLEAVKRVYLEAYT-SILERLETFYGKLTLADRDMVETQSDEILDVSLLVVGDPFGATTHTDIILRARVVHNASIMNAVGACGLQLYNFGQSVSLVFFTDTWKPDSFYDRVKENGMHTLLLLDIKVKEQSEENLARGRK-IYEPPRYMSIPQAIVQLLEVE-STLAIGLSRVGGTLGELHSLVIVG Polpo VIGLGLGDEKDITIKGLEAIKKVYLEFYT-SLLDRMKEYYGKIILADREMVESGCEEMLSVSFLVVGDPFGATTHTDLVMRAKVIHNASIMNAIGCCGLQLYTYGQTISMVFFTETSKPDSFYDRIKSNGLHTLVLLDIKVKEQSIANLLRGNK-IYEKPRFMTINQCIEQLLEIE-ETLCVGLARVGGTMEELHSFVIAG Pucgr2 LIGIGMSSPEDITLSGLKTIQKVYLEGYT-SILEDLQALYGKIILADRDFIETRSDEILDVSLLVVGDPFGATTHADLLLRCTVIHNVSILNAIGSIGINLYHFGQTVSIPFFNSNWRPKSWFKKINQNGLHTLCLLDIKVKEQSDENLARGRK-IYEKPRYMTITTAIEQIISII-EILCIAACRVTGSMAELHSLIILG Punst1 IIGLGLCDEKDITVRGLEAVRRVYLEAYT-SILERLEALYGKVILADRDMVETNSDAILDVCFLVVGDPFGATTHTDIILRARVIHNASIMNAVGACGLQLYNFGQTVSLVFFTDTWKPNSFYDRIAENGMHTLILLDIKVKEQSEENLARGRK-IYEPPRYMSITTAVSQLLEVE-ETLAIAMSRVGGTLAELHSLVIVG Rhior3 VIGLGLSDETDITVKGLEAVKRIYLEAYT-SILERLESYYGKVVIADREMVESDSDSILDVSFLVVGDPYGATTHTDLVIRARVIHNASIMNAVGACGLQLYNFGQTISIVFFTDTWRPDSFYDRIKENGLHTLCLLDIKVKEQSIENMARGRL-IYEPPRYMTVNQAVEQLLEIE-ESLAIGCARIGGTLQELHSLVLVG Rhoto1 LVGLGLHDEKDVTVRGMEAIKRVYLEAYT-SILERLDAFYGKIVVADRDMVEMDSDEILDVAFLVVGDPFGATTHADLLLRADVIHNASVMNAVGALGLALYNYGQTVSIPFFTDSWRPDSWLERVRENGLHTLCLLDIKVKEQSEENLARGRK-IYEPPRYMSVPTAISQLLSLL-ETLAISASRVGGTLAELHSFVIVG Rozal11 IIGLGLADEKDISVKGLEAIKKVYLESYT-SLLERLETFYGKIIEADRECVESFSDEIINVAFLVVGDPFGATTHTDFVLRAIIIHNASIMNVVGVCGLQLYRFGQTVSIPFFTESWKPDSFYDKIKANGLHTLCLLDIKVKEQSEENLLKGKK-IYEPPRFMTVWQALEQILYVE-KRKVIGISKAGASINELHSLIIPS Sacce1 LIGLGLSYKSDITVRGLEAIKRVYLEHYT-SILEELESYYGKIILADRELVETGSKQILDVAFLVVGDPFGATTHTDLVLRAKIIHNASVMNAVGACGLQLYNFGQTVSMVFFTDNWRPDSWYDKIWENGLHTLVLLDIKVKEQSIENMARGRL-IYEPPRYMSIAQCCEQLLEIE-ETPAVAISRLGGTISELHSLVILG Salro LVGLGLQNEKDITVRGLEIVKRVYLEAYT-AILQKLEAFYERVIVADREMVEQQCEDLFDIALLVVGDPFAATTHTDLVTRCKVVHNASIMNAIGCCGLQLYNFGKTVSIVFFTENWRPDSFYDKIKANGMHTLCLLDIKVKEQSIENLMKGRK-VYEPPRYMSVNQCAEQLMEVE-EALAVGVARVGGTLVELHTQPFVS Schco3 IIGLGLCDEKDITVRGLEAVKRVYLEAYT-SILERLEAFYGKLILADRDMVETESDEILDISLLVVGDPFGATTHTDIILRARVVHNASIMNAVGACGLQLYNFGQTVSLVFFTETWKPDSFYDRIKDNGLHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSIPQAVSQLLEIE-ETLAIAVSRVGGTLAELHSLVIVG Schpo1 LIGLGLFDEKDITLRGLETVKRIYLEAYT-SILEKLEELYGKVILADREMVESSSDEILDVAMLVVGDPMGATTHADLVIRARMIHNASIMNAIGACGLQLYKFGQTVSLVFFENNYRPQSFYDHIKENGLHTLVLLDIKVKEQSWENLARGRK-VYEPPRYMSASLAAQQMLEVE-ESLCVAVGRMGGTLQELHSVVLVG Sorma LVGLGLSDETDITVKGLEVVKRVYLEAYT-SILATLESYYGRIVVADREMVESDSDEILDVAFCVVGDPFGATTHTDLVLRARTVPNASIMSGIGAAGLQLYNFGQTVSMVFFLDNWRPASFYDRIKENGLHTLVLLDIKVKEQSLENMARGRK-IYEPPRYMTVGTCAKQMLEIE-ESLAIGCARVGGTLKELHSLILLG Sphar -------------------------------------------------MVEQGADEMLDIAILVVGDPFGATTHSDLMLRAKVIHNVSIMNAVGCCGLQLYSYGETVSICFFTDEWKPDSFYAKIRENGLHTLCLLDIKVKEMTVEEMMKGKYGKFQPPRYMTVNQCIEQLMEIE-ETVCVGLARVGGTMRELHSFVIAG Spipu1 IIGLGLSDEKDITVKGLEAVKRIYLEAYT-SILERLEAFYERVIIADRDMVETESDAILNVAFLVVGDPFGATTHTDLVLRAQPIHNASVMNAVGCCGLSLYQYGQTVSIVFFTETWRPDSFVEKIGANGLHTLCLLDIKVKEQSIENLARGRK-IYEPPRYMSIPTAITQLLSVT-TTIAVGLARLGGTLEELHSLVICG Sporo1 LVGLGLSDEKDVTVRGLEAIKRVYLEAYT-SILDRLETFYGKIIVADRDMVETESDEILDVAFLVVGDPFGATTHSDLLLRADVIHNASVMNACGAVGLALYNYGQTVSIPFFTDNWRPDSWLARIRENGLHTLCLLDIKVKEQSEENLARGRK-IFEPPRYMSVPTAISQLMSLL-ETLAISLSRVGGTLSELHSFVIVG Stehi1 VIGLGLSDEKDITVRGLEAVKRVYLEAYT-SILERLEAFYGKLILADRDMVETESDEILDISLLVVGDPFGATTHTDIILRARVIHNASIMNAIGACGLQLYNFGQTVSLVFFTDSWKPDSFYDRVKENGMHTLVLLDIKVKEQSEENLARGRK-IYEPPRYMSIPLAVSQLLEVE-STLAIAVSRVGGTLQELHSLVIVG Tapde11 VVGLGLADEKDITVRGLEAVRRVFLEAYT-SILARLSAFYGVVTVADRELVESGSDEILNVAFLVVGDPFGATTHTDLIIRARVIHNASIMNAIGACGLQLYNFGQCVSLVFFTETWKPASFYDRVRENGLHTLMLLDIKVKEQSIENMARGRL-IYEPPRYMTVSTAAQQMLEIA-ATWAIGVGRIGATLGELHSLVLLG Thetr MIGLGLGDAKDITVKGLEAVRRVYLEAYT-SVLEELEAFYGVVIVADRELVESGADDTLNIGFLVVGDPFGATTHTDLVVRARVIHNASIMNAAGACGLQLYNFGLTVSVVFFTETWRPDSFYNKVKINGLHTLCLLDIKMKEISDENLAKGRM-IYDPPRFMTVNQCLSQFLEVE-ETQVVALARVGGSIAELHSLVVVG Treme1 IVGLGLSDERDITVKGLDAVKRVYLESYT-SILETLEAFYERVITATREMVELQADEILDVAFLVVGDPLGATTHSDLILRARVIHNASILTALGSTGLQMYSFGQTISLPFYTSTWAPDSWYDRLEENGLHTLVLLDIKVREQSEENMARGRL-IYEPPRFMSPHTAFQQILQTL-STLALSLSRVGGTLAELHSLVIVG Trire2 LVGLGLSDETDITVKGLEVVKRVYLEAYT-SILSVLENYYGRIIVADREMVESNSDEILDVAFCVVGDPFGATTHTDLVIRARTVPNASIMSGIGACGLQLYNFGQTVSMVFFTETWKPSSFYDRIKENGLHTLVLVDIKVKEQSLENMARGRL-VYEPPRYMTVGQCAQQMLEIE-ESLAIGAARVGGTLEELHSLVLLG Umbra1 VIGLGLSDEKDITVRGLEAVKRVYLEAYT-SILSKLSEYYGKVIVADREMVESESDAILNVAFLVVGDPYGATTHTDLVIRARVIHNASIMNAIGACGLQLYNFGQTISIVFFTDTWRPDSFYDRIKENGLHTLCLLDIKVKEQSIENLARGRK-IYEPPRYMTVNQAIEQLLEIE-DTLAIGCARVGGTLQQLHSLVIVG Ustma22 VIGLGLADENDITLKGFHAVKRIYLESYT-SILERLEALYQKVILAHRETVELEAESILNVSFLVVGDPLSATTHTDLILRAKIIHNASIMTAIGSSGLAGYNFGQTVSVPFWTEDWKPDSWLERIGENGLHTLALSDIKVREQSAQDMSRGIL-RYQDPRYMLIPQLISQLISAA-NTLAIALCRMGGTLSELHSLVIVG Walse1 VIGLGLSDEKDITVNGLEAVRRIYLEAYT-SILPKLEEFYGKVTVADRDMVETESDAILDVSFLVVGDPYGATTHTDLILRARVIHNASIMNAAGASGLQLYNFGQTVSIPFFTETWKPASFVPRIADNGSHTLLLLDIKVKEQSIENLARGKK-IFEPPRYMSVSTAVNQLLTLL-ETLAISLSRVGGTLAELHSMILVG Zygro1 LVGLGLSYKSDITLRGLEAVRRVYLEHYT-SILEELESFYGKIILADRELVESGSDKILDVAFLVVGDPLGATTHTDLVLRAKIVHNASIMNAVGSCGLQLYQFGQTISMVFFTDNWRPDSWYDKIMENGLHTLVLLDIKVKEQSIENMARGRL-IFEPPRYMSISQCCEQLLEIE-ETPVVAVSRLGGTIEELHSLVILG [Cluster2083.fasta_al_trimmed; alignment length = 143] Allma1 EPPLMEELGINPGHIWAKAVAVLNPIMDDTDLAGPLLFCLMLGVFLLLSGKFSYIYGMAALGCAAMYAILNLM-STTASVLGYCLLPLVLLSMVSVGPILTWATIGWCTYSSSSMFVTVLEQHALVAYPVGLLYAMFALITAF Ashgo11 EPPLLEELGINFGHILTKTKFVLTPIFNDTDLSGPLLFCLVFGTMLLTAGKFGYIYGVALFGSLSLYQLLRLM-SKTASILGYSFLPLCFLATVGVGYILGLISVVWCTWSSSGFFIYYLNVRVLIAYPLLIFYSVFALMAIF Aspfu1 EPPLLEELGVNFEHIRTKTLTVLNPLMDDSDLYGALLYIVLYGTFLLLSGKYGYIYGVAVFGTVVLHLILSLM-SRSASVLGYCFLPLVLTSLVGIGYLLTTAAVGWCTYSSSGMFCAVAGMRGLVAYPLALFYVVFGIMGIF Aurde31 EPPLLEELGINFGHIRSKTMTVLNPIMDDADLYGPILFYFLLGVFLFFSGKFGYIYGLALMGSASIYVLLNLM-STVASVLGYCLLPMVCVSAISVGYFLAALSVSWCTYAASGIFVAVLDQRFLVAYPISLLYSCFALLSVF Batde5 EPPLLQELDINFNHIKSKGLTVMNPIMDDTDLAGPILFCFLFGGFLFLSGKFGYIYGVATLGWLSMYSILNLM-SRTASVLGYALLPMVLLSSLTIGVILSAVTVVWCTNSSSGMFVTVLEQRLLVAYPVALLYSAFALLAVF Botbo1 EPPLLEELGINFSHIRAKSLTVLNPIMDDADLAGPVMFCFCFGLFLLFSGKFGYIYGVALLGTMSIYALLNLM-SRVASVLGYCLLPMVGVGAISVGYLLSVISIVWCTYSASGIFVAVLDQRLLVAYPVGLLYGCFALLSVF Botci1 EPPLLEELGVNFGHIRSKTLAVLNPIMDDSDLAGPILFFLLFGTFLLFSGKFGYIYGLALLGSSSLHLILSLM-SRSASVLGYCLLPLVLTSVVGIGYVLTTLAIVWCTYSSSGMFCAVGGMRGLVAYPLALFYVGFGIMGIF Caeel EPPLLEELGINFSHIKEKTIAVLNPVIADQDLAGPLVFCLLFGAALLLHGKFGFIYGVGGLGCVGIYALMNLMATCTASVLGYCLLPMALLSIVTAGYIISSLAVLWCSSASSKLFVIALHQRLLVAYPCVLLYSVFALLAIF Canalb1 EPPLLEELGINFQHIRSKTLVVLNPIMADSDLAGPILFVLLFGTLLLLAGKFGYIYGVGLFGIIGLHYLFKFM-SRSASVLGYCLLPLVLISVLGVGYILSAIAVMWCTYSASGFFVSVLNVRPLIAYPLCMFYTVFALMAIF Cangl EPPLLEEIGINFDHIFKKTMYVLRPILNDSDLAGPVIFFMLFGLFLLMAGKFGYIYGVALFGTISLHTLSKQM-ANTASILGYCFLPLCFLSFIGVGHLTGALFVIWSTWSSSGFLNNLLNARTLIAYPLLIFYSVFALMAIF Capow EPPLLEELGINFGQITDKTRLALNPVMDDTDLAGPLIFCLLFGSFLLMSGKFGSIYGVGVVGCLGVYGILNLM-SRTVSVLGYCLLPMVILSSISIGLVLACLSIAWCSFSASHIFVSVLDQLLLVVYPCLLLYGIFALMTVF Catan2 EPPLLEELGINFGHIWDKAFAALNPIMDDTDLAGPLLFCLMFGVFLLMSGKFSYIYGLGAVGCLSMYAILNLM-STTVSVLGYCLLPMVLLSMITADLILSCLSICWCTYSASTMFVTVLEQRLLVAYPVGLLYAIFALMTIF Cioin EPPLLEELGINFDHIYQKTLAVLNPIIKETDLAGPLCFCLALGATLLLGGKFGYIYGIGGLGVVAIYALLSIM-SSVASVIGYCILPMVFLSGCSLGIILTLLTVTWCSLSASKLFVCGFSQQLLVAYPCALLYGVFALLTVF CocheC53 EPPLLEELGVNFKHIQMKTLAVLNPIMDDSDVAGPILFFLIFGTSLLLSGKFGYIYGLAFVGTILLHQILSLM-SRSASVLGYCLLPLVLVAIFGIGYLLTSLAITWCSYSSSSMFTVVGSMRGLVAYPMVLFYGSFGIMAIF Coere1 EAPLMEELGINFQHIKSKTLAVLNPIYDDTDMAGPLLFILVLGTFLLLSGKFGYIYGVALFGTVGIWTILNLM-SHTASILGYCLLPIVVLGSIGLAAIASILPIAWSTYSSATMFVTVLEQRLLVAYPVGLFYTSFALLTVF Conco1 EPGLLEELEINFSHIKTKTITVLNPMMDDVDLAGPVLFCLLLGGALLFGGKFSYIYGVAVVGCASMYLILNMM-SRNASVLGYCLLPIVFLSMLNTMYVLAPVAIFWATYSSSLIFVTVLEQRLLVAYPIALLYTCFSLLTLF Conpu1 EPPLLEELGINFSHIRAKSMTVLNPIMDDADLAGPLLFFFCFGTLLLLSGKFGYIYGFGLLGSASIYTLLNLM-SRTVSVLGYCLLPMVGVGAISVGYLLSVLSIIWCTFSASGIFVAVLDQRLLVAYPVGLLYGCFALLSVF Copci EPPLLQELGINFSHIRAKSLTVLNPIMDDADLAGPIIFFFCFGISLLFSGKFGYIYGVGLFGSVSMYLLLNLM-SRVASVLGYCLLPMVGVGLISVGYLLTILSILWCTYAASGIFVAVLEQRLLVAYPVGLLYGCFALLTVF Croqu1 EPPLLEELGINFDHIKRKSFAVLNPLMDDADLAGPLIFCFCFGMFLLFSGKFGYIYGLALLGDLSLYLLLNLM-SRVASVLGYCLLPLVLLSLVTVGYLLSAFSILWCAYSASGIFVAVLEQRLLVAYPVGLFYATFALLSVF CryneH991 EPSLMEELGINPSHILQKSLAVLNPIMDDADLAGPFVFCFAFAFFLLLSGKFSYIYGVGLLGTTAIYLLLNLM-SRTASVLGYCLLPMVGLGGIGMGYLLSTISIAWCTHSASAIFVAVLRQRLLVAYPVGLLYGCFALLSIF Crypa2 EPSLLEELDINFGHIQAKTIAVLNPLMDDSDIIGPLIFLVCFGFLLALSGTFGYVYGLSLMGSTSLHVIISLM-TRSASVLGYCIIPLLAMSVVGVGIVMTSAAIMWCTYSASGMFCAVGSMRGLVAYPLALFYVGFGIMTIF Debha1 EPPLLEEVGINFQHIKMKTLAVLNPIMADSDLAGPIIFVLLFGTLLLLAGKFGYIYGVGLFGIISLHYLFKLM-SRSASVIGYCLLPLVIVSVIGVGYIFSAFAVFWCTYSASGFFVAVLNVRPLIAYPLAMFYTVFALMAIF Dekbr2 EPPLLEELGVNFGHIKGKTLAVLGFVIQDSDLAGPILFCLLFGILLLLSGKFGYIYGIALFGTISLHLLFRLM-SRTASVLGYCLLPLVLLSALAVGYVLGIIAIFWCTYSSSAFFVRVLNARLLVAYPLAMFYSVFALMAIF Dicdi ELPLLEELGINFDHIRSKTLSVLNPIMDDTDLGGPILFGLLLGFSLLMSGKFGYIYGLGLIGCVSMYIVLNLM-SRVISVLGYCLLPMIFLSFTSLGYILIGFAIVWSTYSASKMFVKVLDQRILVAYPVGLLYTGFALITAF Dmel EPPLLEELGINPNHIFQKTLAVLNPILQDTDMAGPLVFCLTLGGFLLLSGKFSYIYGIGVMGCIFFYCLLSLMVSAVASVLGYCLLPMVVLSGINIGLIVSGISIFWCAISASKLFATAFHQQLLIAYPCAVLYGGFALITIY Enthi EPPLLEELGIDFSLITKRIISRLNP-AIESDVIGSLFFGLLLGVSILLTGKFGYVFGFTIIGSLAEYFILNLL-SVVLTNLGYSSYPLVLLGIASLLIIIAIFAIVWCTYASSRLFTTLQDKKILVAYPMALYFILFVLLVMC Falba EPPLLEELGINFGRIKSKSLHVLNPVAADADLAGPLLFCLLLGAFLLFSGKFSYIYGVAVVGCLGLCMLFNLM-GKTASILGYGLLPMVGLSFITASLFLALLTVSWCTIAGSSLFVKAYEQLVLVFYPIFLFYASFALLTVL Fomme1 EQPLLEELGINFSHIRAKSLTVLNPIMDDADLYGPLIFCFCFATCLLFSGKFGYIYGVALLGSASIYTLLNLM-SRVTSVLGYCLLPMVGVGALSVGLVLASLSIAWCTYAASGIFVAVLQQRLLVAYPVGLLYGCFALFSVF Fusgr1 EPPLLEELGVNFGHIQAKTLAVLNPIMDDSDLAGPLIFFLLFGFILLFSGQFGYIYGLAALGSISLHLILSLM-SRSASVLGYCLLPLVATSLFGIGIVATTAAILWCTYSASGMFCAVGRMRGLVAYPLALFYVGFGIMGIF Galma1 EPPLLEELGINFQHILDKSLTVLNPIMDDADLAGPIFFCFCFGICLLFSGKFNYIYGVGLFGSASLYTLLNLM-SRVASVLGYCLLPMVGVGAISVGYLLSILSILWCTYAASGIFVAVLDQRLLVAYPVGLLYGCFALLSIF Ganpr1 EPPLLEELGINFSHIRSKTLAVLNPILEDADLAGPLVFCLLFGGALLLSGRFGYIYGVGITGVASLYLLLNLM-SRTASVLGYCLLPMVVLSFVRIAVTASLFSVAWCTYSASTMFVKGLDQRALVAYPVFLLYGIFALLAVF Gloin1 EPPLLEELGINFRHIKSKSLAVLNPIMDDTDLAGPLLFCLIFGVSLLLTGKFGYIYGVALLGWASIYVILNLM-SRIASVLGYCLLPLVLLSCVGVGLIASSLAISWCTYSSSTMFVTVLEQRILVAYPVGLLYVCFALMTIF Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------- Klula1 EPSLLEELGINFNRIIAKTKFVLVPIQEDSDLAGPIIFWLMFGILLLTAGKFGYIYGVALFGSLSLHTLLKYM-SRSASILGYAFLPLCVLASLGVGYILGLLTVLWSTWSSSGLFTVSLNVRILIAYPLLIFYSVFALMAIF Lacbi2 EPPLLEELGINFQHIRAKSLTVLNPIMDDADLAGPIIFFFCFGISLLFSGKFGYIYGVGLFGTASIYTLLNLM-SRTASVLGYCLLPMVGLGAISVGYLLSITSILWCTYAASGIFVAVLDQRLLVAYPVGLLYGCFALLSVF Lenti61 EPPLLEELGINFPHIRAKSLAVLNPIMDDADLAGPLLFVFCFGTFLLFSGKFGYIYGVGVLGSLSIYTLLNLM-SRVVSVLGYCLLPMVAVGALSVGYMLSTLSILWCTYAASTIFVAVLEQRLLLAYPIGLLYGCFALLSVF Malgl1 EPGLMEELDINLPHVLDKSLAVLNPMMDDTDLAGPLLFCFVFGMLLLLSGKFGYVYGVGLLGVISIYFLLNLM-SRVTSVLGYCLLPLCLLSAINVGFIVSPLFILWCCTSASGIFVSILNQRVLVAYPVGLFYACFALLSVF Mellp23 EPPLLEELGINFDHIKRKSFAVLNPLMDDADLAGPLIFCFCFGMFLLFSGKFGYIYGLALLGDLSLYLLLNLM-SRVASVLGYCLLPLVLLSLVTVGYLLSALSILWCAYSASGIFVAVLEQRLLVAYPVGLFYATFALLSVF Mnele EPPLMEELGIDLQQIYQTTMTVLNPLMDDPDLSGPLMFCLGFGSLLLLSGKFGYIYGVALIGAASMYTLLNLM-SITVSVLGYCMLPMCILAAVSAGIIVSIITVSWAAFASSKLFVSVLDQQPLVAYPCAIMYGIFAVLTVF Monbr EPPLLEELGINFDHIRSKTLAVLNVLMDDTDLAGPLMFCLLFGAFMLASGKFGYIYGVAVMGCLGLYMVLRLM-STTASVLGYSLLPMVALSSISIGLSLAATSIAWCTHSAARIFTSLASTQSLVLLPLSVFYVRVSVPQ-- Morel2 EPPLLEELGINFSHIKTKSFTVLNPIMDDTDLAGPLLFCLAFGTFLLLSGKFGYIYGVAVVGCSVLFLILNLM-SKTASVLGYCMLPLVMLSSVSTGYILSALAIAWCTYSSSGFFTAVLDQRFLVAYPVGLFYGCFALMTVF Mucci2 EPPLLEELGLNFGHIKTKSLAVLNPIMDDTDLAGPLLFIFLFGTFLLLSRKFGYIYGVGVMGVVSIYLILNLM-SRTASVLGYCLLPMVMLSGFSVGTALTVISILWCTYSSSGMFSSVLEQRFLVAYPVGLFYACFALMTFF Mydma EPPLLEELGINFDHIGLKTKSVLNPIMDDTDLAGPLVFCLAFGAFLLLSGKFGYIYGVGVLGSISMYAVLNLM-SCVISVLGYCLLPMVILSGVSVGTILTGLVILWCSISASKLFVTVLHQQPLVAYPCALLYGVFALLTVF Neucr2 EPPLLEELGVNFGHIRSKTLAVLNPLMDDSDMAGPVLFFFLMGTFLLLSGRFGYIYGLALFGSISLHVILSLM-ARSASVLGYCLLPLVATSLVGIGIVLTSAAILWSTYSASGIFCAVSSMRALVAYPLALFYVGFGIMSVF Orpsp11 EPPLLEELGISFTDIKKKALVVLYPNMGNPDLVGPILFCLIFGSILLLRGKFGYIYGVASLGSIGIHLIFNLM-SNTGSILGYCLLPIVVLSALCT----------------------------------------------- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 EPPLLEELGINFGHIKTKSLTVLNPIMDDADLAGPLLFLLLFGMCLLLSGKFGYIYGVGVLGVVSIYLILNLM-SRTASVLGYCLLPMVMLSGFSVGVVLSVLSILWCTYSSSGMFTSVLEQRYLVAYPVGLFYASFALMTVF Picst3 EPPLLEELGINFQHIKDKTRAVLNPIMNDSDLAGPILFVLLFGTLLLLSGKFGYIYGVGVCGTVGLHYLFKFM-SRSTSVIGYCLLPLVLISVLGVGYLLSAFAVLWCTYSASGFFVAVLNARPLVAYPLCMFYTVFAFMVIF Plicr1 EPPLLEELGINFSHIRAKSLTVLNPIMDDADLAGPLLFCFCFGTFLLFSGKFGYIYGVGLLGSVSIYTLLNLM-SRVVSVMGYCLLPMVGVGAISVGYLLSILSIVWCTYAASGIFVAVLDQRLLVAYPVGLFYGCFALLSVF Polpo ELPLLEELGINFDHIKKKTLSVLNPIMDDTDLGGPIFFDLVLGFSSLMSGKFGYIYGLGLIGCLSMYVVLNLM-SRVISVLGYCLLPIVFLSFVSLGYILIFVAIFWSTYSASKMFVKTLDQRILVAYPVGLLYTGFALITAF Pucgr2 ------ELGINFDHIKRKSFAVLNPLMDDADLAGPLVFCFCFGMFLLFSGKFGYIYGLALLGDLSFYLLLNLM-SRVASVLGYCLLPLVLLSLVTVGYILSILSILWCSYSASGMFVSVLEQRLLVAYPVSLFYATFALLSVF Punst1 EPPLLEELGINFTHIRAKSMTVLNPIMDDADLAGPLLFILCFGMFLLLSGKFGYIYGVGLLGSMSVYMLLNLM-SRVVSVLGYCLLPMVGVGAVSVGSILSIISIAWCTYAASGIFVAVLDQRLLVAYPVGLLYGCFALLSVF Rhior3 EPPLLEELGLNFGHIKTKSLTVLNPIMDDTDLAGPLLFIFLFGTFLLLSRKFGYIYGVGVFGVASIYLILNLM-SRTASVLGYCLLPMVMLSGLGVGTILTVISTLWCTFSSSGMFTSVLEQRILVAYPVGLFYACFALMTFF Rhoto1 EPPLLEELGINFDHILQKSLTVLNPIMDDADLAGPLVFCFVFASFLLLSGKFSYIYGVALIGSVSMYALLNLM-SRTASVLGYCILPLVLLSMLSVGYIISSLIVIWCSYSASSIFASVLHQRFLVAYPVGLLYTAFSLF-VF Rozal11 EPPLFEELGINFSHVKSKSLQVMNPFIDDEDLAGPLVFILSYGAFLLFSGKFGYIYGLALLGCISVYVILNLM-SRTASVLGYCLLPLVFLALLSLGLVISLMCILWCTYSSSTIFSKVLEQRILIAYPIGLLYTIFALMTIF Sacce1 EPPLLEEIGINFDHIITKTKMVLIPILNDSDLAGPLIFFLLFGLFLLMAGKFGYIYGVALFGTISLHNLSKLM-SNTASILGYCFLPLCFLSLLGIGYVVSVLFVIWSTWTSSGFLNSLLNARLLIAYPLLIFYSVFALMVIF Salro EEPLLQELGINFRHIADKTGAVLNVLMDDTDLAGPLVFCVAYSAFLLMSGKFGSVYGVAVVGCLGMYTVLSLM-TRTASVLGYSLLPMVGLSSIAIGSLLAAISIAWCTHSASRIFTSVMRDS-------------------- Schco3 EPPLLEELGINFSHIRGKSMTVLNPIMDDADLAGPIIYVFCFGMFLLLSGKFGYIYGVGLFGSMSLYILLNLM-SRVTSVLGYCLLPMVGVSAVSVGYLLSFLSVLWCTYSASGIFVSVLQQRVLVAYPVLLLYGCFALLSVF Schpo1 EPSLLEELEINFGHIKQKTTHVLNPIMDDTDMAGPILFCLLFSTFLSLHGRFGYIYGIALLGSLSLHFVLRLM-SRTVSVLGYSLLPLVVIAFFKNGYALAALACIWCTYAASAMFVGILNMRFLVAYPIALFYGVFAVITVF Sorma EPPLLEELG---------TLAVLNPLMDDSDMAGPVLFFFLMGTFLLLSGRFGYIYGLALFGSISLHVILSLM-ARSASVLGYCLLPLVMTSLVGIGIVLTSMAILWSTYSASGIFCTVSSMRALVAYPLALFYVGFGIMSVF Sphar ----------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 EPPLLEELGINFSHIKKKGVTVLNPIMDDTDLAGPILFVLLFGGFLLLSGKFGYVYGVAMLGCVSVYAILNLM-SRTASVLGYCLLPMVVLSSVATGLILSALSVLWCTYSASKMFTTVLEQRLLVAYPVGLLYSAFALLAIF Sporo1 ----LSELGINFDHILAKSLTVLNPIMDDADLAGPLVFCFVFASFLLLSGKFSYIYGVALIGSASMYALLNLM-SRTASVLGYCILPLVLLSMFNVGYLLSSIFVLWSTYSSSSIFATVLHQRFLVAYPVGLLYSAFSLF-VF Stehi1 -------------------MTVLNPIMDDADLAGPLLFCFCFGTFLLFSGKFGYIYGVGLLGSASIYTLLNLM-SRVSSVLGYCLLPMVGVGALSVGYVLALVSVTWCTYAASGIFVAVLDQRLLVAYPVGLLYGCFALLSVF Tapde11 ESTLYEELGVNFNHIKVKTMTVLNPIMDDTDLFGPLIFGVLFGFILLLSGKFGYVYGCALMGCVSLWTILSLM-ARIASVLGYCLLPLVSVSAFGLGYGLTAAAVLWSTNSASAIFVSVLNMRVLVAYPVALFYSIFAILSLF Thetr EPPLLEELGIDFGDIKSKSLAVLHPVMDDYDLAGPIVFAALLGFFLLMAGKFNIIYGVGSAGCAAIFLLLNMM-SLVASVLGYCLLPIVGLSAAALGMALSALVVAWCTHSASSMFVARLQQRWLVFYPILLHFSTFALITMF Treme1 EPSLMEELEINPSHILQKSLTVLNPIMDDADLAGPLVFCLAFAFFLLLSGKFSYIYGVALLGTTAIYLLLNVM-SRTASVLGYCLLPMVGVGGIGMGYLLSVGSIVWCTHSASGIFVAVLRQRLLVAYPVGLLYGCFALLSIF Trire2 EPSLREELGVDFGHMQAKTLAVLNPVMNDSDLAGPLLFVVLFGAFLLCSGSFGYVYGLALMGSTMLYMILSLM-TQNASVLGYCFLPLVLTSLIGVGYIITSLAICWATSRSSAIFCAVGDMRGLVAYPVALFYVGFGIITIF Umbra1 EPPLMEELGVNFQHIRAKSMAVLNPIMDDADMAGPLLFILMFGVFLRITGKFGYIYGVGVLGMVSIFLILNMM-SRTASVLGYCLLPMVMLSGFSVGFILSVVSILWCTFSSSGMFTSVLEQRFLVAYPVGLFYACFALMTVF Ustma22 EPPLMEELGINIGHIVDKTLTVLNPMMDDADLAGPLLFCFLFGMTLLLAGKFGYVYGVALFGAISIYTLLNLM-SRVASVLGYCLLPLCILSTASIGYIVSPLFILWCSTSASGIFVSILEQRLLVAYPVGLFYACFALLSVF Walse1 EDPLLTELGINFSHITTKSLAVLNPLMDDADLAGPLVFWGAFGLALLLSGKFGYIYGVALIGSLSIYSLLNVM-SRTASVLGYCLLPMVILSVISVGYGLSAFTTLWCTFSASGIFVTVQEQRLLVAYPVGLLYACFALLSVF Zygro1 EPPLLEEIGINFAHVITKTRIVCNPILGDSDLAGPLIFFLLFGLFLLLAGKFGYIYGVALFGTVSLHNLSKFM-GNTASVLGYCFLPLCFLSLIGVGYALGAIFVAWSTWSSSAFFNSLLDARALIAYPLLIFYTVFALMAIF [Cluster2088.fasta_al_trimmed; alignment length = 87] Allma1 LMAVVGDEDTVTGLLLAGIGHINFLVV-DIEEFVQDLL-KRRDIAIILINQHIAETIRGIIDAFPTILEIPSKDHPYDPSKDSVLKR Ashgo11 LIAVIADEDSITGLLLAGVGQVNFFIYNEVSEAFEKFTSVRDDIAILLINQHVAEEIRAQIDPFPAILEIPSKDHPYDPEKDTVLRR Aspfu1 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIEKAFQNFTQERKDIAVLLINQHIAERIRHSVDPFPAVLEIPSKDHPYDPEKDSVLKR Aurde31 LIAVIGDEDSITGLLLAGVGHVNFLIV-DIEGAFQEFT-ERKDVAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPSKDSILKR Batde5 LIGVIGDEDTVTGMLLAGIGHINFLVV-DIEEMFEELT-KRKDMAIILINQHIAEDIRAQLEAFPTVLEIPSKDHPYDPSKDSVLKR Botbo1 LLAVIGDEDSITGLLLAGIGHINFLVV-DIESAFEEFT-ERSDIAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPSKDSILKR Botci1 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIEEAFERFTTERKDIGILLINQHIAERIRHRVDAFPALLEIPSKDHPYDPEKDSVLRR Caeel ILAVIGDEDTVVGFLLGGVGELNYLIV-DIEEAFNGFC-ARDDIAIILINQHIAEMIRYAVDSIPAVLEIPSKEAPYDPSKDSILNR Canalb1 LVAAIADEDTVTGLLLAGIGQINFLTVIPIEEAFTTFTSTRDDIAILLINQHLADLIRFKVDAFPAILEIPSKDHPYDPEKDSILKK Cangl LLAVIADEDTTTGLLLAGVGQINFFVFQEVGEMFDKFTEERNDIAILLINQHIAELIRSRVDPFPAILEIPSKDHPYDPEKDSVLKR Capow --------------------------------------------------------------------------------------- Catan2 LIGVIGDEDSVTGLLLAGIGHINFFIV-DIEEAFQAML-KRRDMAIILINQHVAEQIRESMDAFPTILEIPSKDHPYDPSKDSVLKR Cioin LLAVIGDEDTCTGFLLGGIGELNFMVV-EIEEQLRLFL-SRKDIAIVLISQSIADVVRYVIDPIPSVLEIPSKDAPYDPSKDSILRR CocheC53 FLAVIGDEDTCTGMLLAGVGHVNFLVV-DIEAAFDRFTNERKDIAILLINQHIAERIRHRVEAFPSLLEIPSKDHPYDPEKDSVLKR Coere1 LIASIGVEDTMTGLLLAGIGDINFLNV-DIEKAFTSFT-GRKDIAIILINQNIADRIRGILDPFPTVLEIPSKDHPYDPSKDSVLKR Conco1 FLAVIGDEDTVTGLLLAGVGHINFLVV-DIEESFNSFI-ERKDIAIILINQHIAEEIRPLIEAFPAVLEIPSKDHPYDPTKDTILTR Conpu1 --------------------------------------------------------------------------------------- Copci LIAVIGDEDSITGLLLAGIGHINFLIV-DIEAAFQEFT-ERKDIAILLINQHIAEKIRPTVDAFPTLLEIPSKDHPYDPSKDSILKR Croqu1 LIATIGDEDTITGLLLAGTGHINFLVV-DIQATFDEFTTVRDDIAIVLINQHIAEKIRPSVDAFPALLEIPSKDHPYDPDKDSVLKR CryneH991 LIAVIGDEDSVTGLLLAGIGHINFLIV-DIESAFQDFT-ERKDVAILLINQHIAERIRPTVDAFPALLEIPSKEHPYDPAKDSVLKR Crypa2 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIESTFDKFIE-RKDIAIILINQHVADKIRHRIDAFPTILEIPSKDHPYDPEKDSVLRR Debha1 LLAAIADEDSVTGLLLAGVGQINFLTVIPVEEAFERFTTKRDDIAILLINQHIADLIRYRVDAFPAILEIPSKDHPYDPEKDSILKK Dekbr2 LMAAIGDEDTVTGILLAGIGQVNFYVA-SLERKFDEFI-NRDDVAILLINQFLADKIRVLIDPFPAILEIPSKDHPYDPEKDSILRR Dicdi LVAVIGDEDVVTGFLLAGVGQKNFLVV-DIETAFKSFT-TRNDIAIIMITQKVADEIRYLIDVIPTILEIPSKDHPYDPKKDSVMLK Dmel LLAVIGDEDTCVGFLLGGIGEVNFMVV-EIEECFKKFL-RRPDIVIILINQVYADMIRPTVDAVPTVLEIPSKQHPYDSSRDSILKR Enthi QIAIIGDEDSVTGFLLAGIGSINFLIV-DIAQTFNEYV-NRTDIAIVLITQNVADSMRDILDYLPVIMEIPCKDHPYNPDTDSVMVR Falba LIAVIGDHDTVTGMLLAGAGNVNFLVV-SIEKAFNKFT-TRRDISVVLITQPVAEDIRYLVDPIPAVLEIPSKETPYDPSKDSIMRR Fomme1 LLAVIGDEDSITGLLLAGIGDVNFLVV-DIESAFEEFT-ERADIAILLINQHIADKIRPTVDAFPALLEIPSKDHPYDPSKDSVLKR Fusgr1 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIEAAFDRFTEDRKDIGIVLINQHIAERIRHRIDAFPAVLEIPSKDHPYDPEKDSVLRR Galma1 LIAVIGDEDSITGLLLAGIGHINFLVV-DIEGAFQEFT-ERKDIAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPSKDSILKR Ganpr1 LIAVIGDEDTVTGLLLAGVGHINFLVV-DVEETFNEFL-RRRDVAIILINQHVADEIRQAIDAFPTILEIPSKDHPYDPSKDSVLKR Gloin1 FIAVIGDEDSVTGLLLAGIGHVNFLVV-DIEDAFIEFT-KNKEIAIILINQHVANDIRQLLDAFPTVLEIPSKDHPYDPEKDSVLKR Hisca1 --------------------------------------------------------------------------------------- Klula1 LIAVIADEDTTTGLLLAGIGQVNFVVYNELSDAFVKFTETRPDIAILLINQHIADQIRPLVDAFPAILEIPSKDHPYDPEKDSVLRR Lacbi2 LIAVIGDEDSITGLLLAGIGHINFLVV-DIEAAFQEFT-ERKDIAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPSKDSILKR Lenti61 LLAVIGDEDSVTGLLLAGIGNVNFLVV-DIEQAFEEFT-TRKDIAILLINQHIAEKIRPMVDAFPALLEIPSKDHPYDPSKDSILKR Malgl1 LIALIADEDSTTGFILAGIGDVNFFVV-DIEDTFFKFTKDRNDIAIVLINQHIADKIRPLVDAFPAVLEIPSKDHPYDPSKDAVLKR Mellp23 LIATIGDEDSITGLLLAGTGHINFLVV-DIQATFDEFTTGRDDIAIVLINQHIADKIRPSVDAFPALLEIPSKDHPYDPEKDSVLKR Mnele LMGLVGDEDTCTAFLLGGIGELNFLVV-KIESNLKRLM-ARKDIGIILINQHIANDVRHIIEPIPALLEIPSKEHPYDAAKDSILKR Monbr LIAVIGDEDTCTGFLLAGVGDINYLVV-NIEDAFRHFV-ERDDIAIILINQMIAEDIRYLLDAIPAVLEIPSKEQPYDSSKDSILRR Morel2 FMAAIGDEDSITGLLLAGIGHINFLVV-DVEDAFQEFC-KRKDIAIILINQHIAEEIRTLIDAFPTILEIPSKDHPYDPEKDSVLKR Mucci2 FIAVIGDEDSVTGLLLAGIGNVNFLVV-DIEETFIEYT-KRKDIAIILINQHIAEDIRELVDAFPAILEIPSKDHPYDPEKDSVLKR Mydma IIAVIADRDTCTGFLLGGIGEINFLVV-GIQDAFVKFT-TRADVAIILITQKVAEEIRHLIDPIPAVLEIPSKDCPYDSSKDSILKR Neucr2 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIEAAFDRFTTERKDIGIVLINQHIADRIRHRVDAFPTVLEIPSKDHPYDPEKDSVLRR Orpsp11 --------DTVTGLLLAGIGHINFLIV-DIEETFLEFT-HRKDIAIVLINQHVADMIRQLVDAFPSVLEIPSKDHPYDPAKDSVLKS Pench1 FLAVIGDEDSVTGLLLAGVGHVNFLVV-DIERAFQNFTQERKDIAVLLINQHIAERIRHSVDPFPAVLEIPSKDHPYDPEKDSVLKR Phybl2 FLAVIGDEDSVTGLLLAGIGHVNFLVV-DVEETFLEFT-KRKDIAIILINQHVAEEIRELIDAFPTVLEIPSKDHPYDPEKDSVLKR Picst3 LLAAIADEDSVTGLLLAGVGQVNFITVVPVEDAFENFTAERDDIAILLINQHIADLIRYKVDAFPAILEIPSKDHPYDPEKDSILKK Plicr1 LIAVIGDEDSITGLLLAGVGHINFLVV-DIEASFQEFT-ERKDIAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPSKDSVLKR Polpo LVAVIGDEDIVTGFLLAGCGQKNFLVV-DIEQSFKNFT-QRNDIAIILISQKIADEIRPLIDVIPTILEIPSKDHPYDPSKDSVMLK Pucgr2 LIATIGDEDSITGLLLAGTGHVNFMVV-DIQKAFDEFTTERDDIAIVLINQHVADKIRPSVDAFPALLEIPSKDHPYDPEKDSVLKR Punst1 LLAVIGDEDSITGLLLAGIGHINFLIV-DIEAAFEEFT-ERSDIAILLINQHIAEKIRPTVDAFPALLEIPSKDHPYDPNKDSILKR Rhior3 FIAVIGDEDSVTGLLLAGIGNVNFLVV-DIEDTFIEYT-KRKDIAIILINQHVAEDIRELVDAFPAVLEIPSKDHPYDPEKDSILKR Rhoto1 LIATIGDEDTITGLLLAGTGHINFLVV-DIESAFAEFT-ERSDIAILLINQHVAEMIRPTIEAFPALLEIPAKDHPYDPSKDSVLKA Rozal11 LIAIIGDEDTVTGCLLAGVGHVNFLVV-DIEETFKTFL-SRKDIAIILINQHIAEEIRHLLEAFPSVLEIPSKDHPYDPEKDSVLKR Sacce1 LIAVIADEDTTTGLLLAGIGQINFFVYQEITDKFNHFTEERDDIAILLINQHIAENIRARVDAFPAILEIPSKDHPYDPEKDSVLKR Salro LIAVIGDEDTCTGFLLGGIGDINYLVV-TIEDSFRKLV-TRDDIAIILINQSIAEEIRHLLDAIPAVLEIPSKHQPYDSSKDSILNR Schco3 LIAVIGDEDSITGLLLAGVGHINFLIV-DIEAAFQEFT-ERKDIAILLINQHVAEKIRPTVDAFPALLEIPSKDHPYDPSKDSILKR Schpo1 LVSVIGDDDTVTGMLLAGTGQVNFFII-TIAEAFDDYTTKRKDIAIVLINQFAAERIRDRIEAFPAVLEIPSKDDPYDPEKDSILRR Sorma FLAVIGDEDSVTGLLLAGIGHVNFLVV-DIEAAFERFTTERKDIGIILINQHIADRIRHRIDAFPTVLEIPSKDHPYDPEKDSVLRR Sphar LIAVIGNEDTVTGFLLAGVGDVNFLVV-KIEEAFRSFT-QRPDISVILINQNIATEIRYAIDPVPAVLEIPSKDTPYDPSKDSILAR Spipu1 LIAVLGDEDSVTGLLLAGIGHINFLVV-DIEESFEEFT-NRKDVAIILITQQVADEIRHILDAFPTILEIPSKDRPYDPSKDSVLKR Sporo1 LIATIGDEDTITGLLLAGTGHINFVVV-DIESAFAEFT-ERSDVAILLINQHIADQIRPIVEAFPALLEIPSKDHPYDPSKDSVLKR Stehi1 --------------------------------------------------------------------------------------- Tapde11 LIASIADEDTTTGLLLAGTGEKNFLIV-SIEETFDNFTNDRDDIAILLINQHIAEKIRSRLDAFPAVLEIPSKEYPYDPEKDSVMKR Thetr --------------------------------------------------------------------------------------- Treme1 LIAVIGDEDSVTGLLLAGIGHVNFLIV-DIEGAFQDFT-ERKDIAILLINQHIAERIRPAVDAFPALLEIPSKEHPYDPAKDSVLKR Trire2 FLAVIGDEDSVTGLLLAGIGHINFLVV-DIESAFDSFTE-RKDIGIVLINQHIADRIRHRVDAFPTVLEIPSKDHPYDPEKDSVLRR Umbra1 LIAVIGDEDSVTGLLLAGIGHTNFLVV-DIETAFQEFT-SRKDIAIILINQHVAEDIRELIDAFPTVLEIPSKDHPYDPEKDSVLKR Ustma22 LIALIADEDSTTGLLLAGIGNVNFLIV-DIESCFHHFTNERKDIAILLINQHIAEKIRPVVDAFPALLEIPAKDHPYDPAKDSVLKR Walse1 LIAAIGDEDTITGLLLAGIGQVNFYVH-DLEEHFREFTQERDDIAILLINQHIAELIRPLVEAFPALLEIPSKDHPYDPEKDSVLKR Zygro1 LIATIADEDTNTGLLLAGVGQINFFVYQEVRQAFDKFTKDRDDVAILLINQHIAELIRSDLDAFPAVLEIPSKDHPYDPEKDSVLKR [Cluster2093.fasta_al_trimmed; alignment length = 98] Allma1 GGKTRRRGKNKRELMFKEDGQEYAQVVKMLGNGRLEAQCFDNTKRLATIRGKMRKKVWINQGDIILVGLREFEDEKCDVIHKFSADEARALKQHGELP Ashgo11 GGKKGRRGKNKRELIYKDEGQEYAQISKMLGNGRVEATCFDGVKRMAHIRGKLRKRVWMSQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKTQGELP Aspfu1 GGKNRRRGKNKRELVFKEEGQEYAQVVKMLGNGRLEAMCFDGEKRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVIMKYTADEARSLKAYGELP Aurde31 GGKNRRRGKNKRELVFKEDGQEYAQVIKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIILLSLREFQDDKADVIVKYTADEARSLKAYGELP Batde5 ------RGKNKRELVFKEDGQEYASVTKMVGNGWVETSCCDGEKRLAHIRGAFRKKIWIGVGDVLLLGLRDYQDTKADVILKYTPDEARLLKSYGELP Botbo1 GGKNRRRGKNKRELVFREDGQQYAQVIKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIILLSLREFQDDKADVIVKYTADEARNLKAYGELP Botci1 GGKNRRRGKNKRELTFKEEGQEYAQVIKMLGNGRLEALCFDGTRRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVILKYSADEARSLKAYGELP Caeel GGKNRRRGKNKRELDLKEEGQEYGQVSKMLGNGRVQVFCFDGKQRVCHIRGKLRKKVWINVGDIILVGLRDYQDDKGDVILKYTPDEARRLKNEGLIP Canalb1 GGKNRRRGKNKRELIYKEEGQEYAQITKMLGNGRIEVSCFDGIKRMGHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNSDEARTLKNVGELP Cangl GGKKGRRGKNKRELIYKEEGQEYAQITKMLGNGRVEASCFDGIKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKSQGELP Capow GGKNRRRGKNKRELVFKEDGQEYAQVVKMLGNGRLEAVCFDGQRRLCHIRGKMRKKVWIAQGDIILIGLRDYQDDKGDVILKYTADEARNLKLYGELP Catan2 GGKTRRRGKNKRELIFKEDGQEYAQVLKMLGNARIELQCFDGEKRLGTIRGKMRKKVWINVGDIVLVGLRDFQDEKCDVILKYSADEARNLKTYGELP Cioin GGKNRRRGKNKRELIFKDDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQSDIILIGLRDYQDQKADVIMKYNAEEARNLKLYGELP CocheC53 GGKNRRRGKNKRELVFKEEGQEYAQVVKMLGNGRLEAQCFDGARRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVIMKYSADEARSLKAYGELP Coere1 GGKNYRRGKNKRELQLKEEDQEYALVLKMLGNGRLESQDIHGVKRLAHIRGKMRKKVWISQGDYVLLSLREYQDEKCDVIHKYKPEEVELLMKIGQIP Conco1 GGKNRRRGKNKRELVFKEEGQEYAQVLKLLGNGRIDAQCFDGVKRLALIRGKMRKKVWINAGDIVLLSLRDFQDDKADVILKYNPDEARMLKSYGELP Conpu1 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIVKYTADEARNLKAYGELP Copci GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIVKYTADEARNLKAYGELP Croqu1 GGKNRRRGKNKRELVFKEDGQEYAQVTKMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINQGDIILISLRDFQDDKADVIQKYTTDEARNLKAYGELP CryneH991 GGKNNRRGKKKRELIFKEDGQEYAQVVKMLGNGRLEAKCQDGESRLAQIRGQMRKKVWIVVGDIILLSLREFQDDRADVIHRYTPDEARNLKTYGELK Crypa2 GGKNRRRGKNKRELTFKEDGQEYAQVVKMLGNGRLEAQCFDGTRRLGNIRGKLRKKVWINQGDIILLSLRDYQDDKGDVILKYTADEARSLKAYGELP Debha1 GGKNRRRGKNKRELIYKDEGQEYAQITKMLGNGRIEVSCFDGEKRMGHIRGKLRKKVWMSQGDIILVSLRDFQDDQCDVIHKYNSDEARTLKNVGELP Dekbr2 GGKNRRRGKHKRELVLKEEDQEYAQITKMLGNGRVEATCFDGKKRIAHIRGKLRKKVWMQQGDIILVALRDFQDNQCDVVHKYNSDEARTLVSMGELP Dicdi GGKNRRRGKNKRELQFKEEGQEYAQVLRMLGNGRLEASCFDGEKRLCHISGRLRKKEWINNGDIILIQLRDYQNDKADVILRYNVDEARNLKTYGELP Dmel GGKNRRRGKNKRELIFKEDQQEYAQVTKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINQGDIILVGLRDYQDSKADVILKYTPDEARNLKTYGEFP Enthi GGKRSGARKGIHELVFKEEGQEYGQVTRMLGNGRLEAYCFDGKTRQCHIRGQMQRKVWINVNDVILVSLREYEDGKADVIKKYNSDEIIQLKKYKEIP Falba GGKNRRRGKNKRELILRDEMQEYAQVTKMLGNGRIEAFCFSGKTRQCHIRGKMRKKVWINVGDIVLISLRDFQDDKADVILKYSVEEARKLKQNKEIP Fomme1 GGKNRRRGKNKRELVFKEDGQEYAQVTKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIILLSLREFQDNKADVIVKYTADEARSLKAYGELP Fusgr1 GGKNRRRGTKRRELTFKEDGQEYAQVIKMLGNGRLEALCFDGSKRLANIRGKMRKKVWINQGDIILLSLRDFQDNKGDVILKYTADEARTLKSYGELP Galma1 GGKNRRRGKNKRELVFREDGQEYAQVIKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIVLLSLRDFQDDKADVIVKYTADEARNLKAYGELP Ganpr1 GGKNRKRGKNKRELIFKEDGQEYAVVTKMLGNGWVESQCVDGKKRLAHIRGAFRKKVWITVGDVILLGLRDYQDDRSDIIMKYNAEEARTLKAYGELP Gloin1 GGKNRRRGKNKRELIFKEDGQEYAQVVKMLGNGRLEAQCFDGEKRLAHIRGKLRKKVWINQGDIILISLRDYQDAKADVILKYTTEEARNLKTYGELP Hisca1 GGKNRRRGKNKRELTFKEEGQEYAQVVKMLGNGRLEALCFDGEKRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVILKYNADEARSLKAYGELP Klula1 GGKKGRRGKNKRELIYKEEGQEYAQITKMLGNGRVEASCFDDVKRMAHIRGKLRKRVWMSQGDIILVSLRDFQDDQCDVVHKYNTDEARTLKSQGELP Lacbi2 -------------------------------------------------------------------------------------------------- Lenti61 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINQGDIILLSLREFQDDKADVIVKYTADEARSLKAYGELP Malgl1 GGKNRRRGKNKRELVFKDESQEYAQVLRMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINNGDIILLSLREFEDGKADVIQKYTPDEARSLKQHGELP Mellp23 GGKNRRRGKNKRELVFKEDGQEYAQVTKMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIQKYTTDEARNLKAYGELP Mnele GGKNRRRGKNKRELVFKEHGQEYAQVLKLLGNGRLEAQCFDGVKRLCHIRGKLRKKVWINQGDIILIGLRDYQDSKADVIQKYNPDEARNLKAYKELP Monbr GGKNRRRGKNKRQLIFKEEGQEYAQVVRMLGNGRVECFCFDGETRLGHIRGKMRKKVWINTGDIILIGLRDFQDSKCDVIAKYNADEARELKSHGELP Morel2 GGKNRRRGKNKRELVFKEDGQEYAQVLKMLGNGRVEAQCFDGEKRLAHIRGKMRKKVWINQGDIILISLRDFQDDKADVILKYNTEEARNLKAYGELP Mucci2 GGKSRRRGKNKRELVFKEEGQEYAQVLKMLGNGRVEAQCFDGVKRLALIRGKLRKKVWINQGDIVLLSLRDFQDEKADVIQRYNPDEARQLKSYGELP Mydma GGKNRRRGKNKRELVFKEEGQEYAQVIKMLGNGRLDALCFDGTKRLCHIRGKLRKKVWINAGDIILLGLRDYQDTKADVILKYTPDEARNLKSYGELP Neucr2 GGKNRRRGKNKRELTFKEEGQEYAQVIKMLGNGRLEAMCFDGVKRLGLIRGKLRKKIWINNGDIILVSLREYQDEKGDVILKYSADEARSLKAYGELP Orpsp11 GGKNRKKGKNKRELVFKEEGQEYAIVTKMLGNGWVEAQCCDNVKRLAHIRGAFRKKVWIVQGDLVLLSLRDFQDDKADVILKYTADEASSLKKYGELP Pench1 GGKNRRRGKNKRELVFKEEGQEYAQVVKMLGNGRLEALCFDGEKRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVIMKYTADEARSLKAYGELP Phybl2 GGKNRRRGKNKRELIFKEEGQEYAQVTKMLGNGRVEAQCFDGVRRLAHIRGKLRKKVWISQGDIVLISLREYQDEKADVLLKYNPDEARALKSYGELP Picst3 GGKNRRRGKNKRELIYKEDGQEYAQITKMLGNGRIEVSCFDGIKRMGHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNSDEARTLKNVGELP Plicr1 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIVLLSLRDFQDDKADVIVKYTADEARNLKAYGELP Polpo GGKNRRRGKNKRELQFKEDGQEYAQVIKMLGNGRLEAQCFDGAKRLCHISGRLRKKEWINSGDIILLQLRDYQDDKADVVLRYTIDEARSLKTLGELP Pucgr2 GGKNRRRGKNKRELVFKEDGQEYAQVTKMLGNGRLEAMCFDGEKRLAHIRGKMRKKVWINQGDIILISLRDFQDDKADVIQKYTTDEARNLKAYGELP Punst1 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAVCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIVKYTADEARSLKAYGELP Rhior3 GGKSRRRGKNKRELVFKEEGQEYAQVVKMLGNGRVEAQCFDGVKRLALIRGKLRKKVWINQGDIVLLSLREFQDEKADVIQRYNPDEARQLKAYGELP Rhoto1 GGKNRRRGKNKRELVFKEEGQEYAQVLKMLGNGRVEAMCFDGEKRLAHIRGKMRKKVWINQGDIILLSLRDFQDDKADVIQKYSADEARKLKQYGELP Rozal11 GGKNRRKGKSKRELIYKDEEQEYGQVVKMLGNARVELSCFDGKKRQGHIRGKMRKKVWIGTGDIVLCSLRDFQDDKCDIIAKYFPDEARQLVAEGELP Sacce1 GGKKGRRGKNKRELIYKEEGQEYAQITKMLGNGRVEASCFDGNKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLKNQGELP Salro GGKNRRRGKNRRELVFKDEGQEYALVTRMLGNGRCECSCFDGTTRLGHIRGTMRKKVWINKDDIILVSLRDYQDGKCDIILKYTMDEARNLIKNGQLP Schco3 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEAQCFDGEKRLAHIRGKMRKKVWINQGDIILISLREFQDDKADVIVKYTPDEARNLKAYGELP Schpo1 GGKNRRRGKNKRELTYAEEGQMYAQVTKMLGNGRIEAACFDGVKRLGHIRGKLRKKVWINQGDIILLSLREFQDEKGDVILKYTADEARTLKNQGELP Sorma GGKNRRRGKNKRELTFKEEGQEYAQVIKMLGNGRLEAMCFDGVKRLGLIRGKLRKKIWINNGDIILVSLREYQDEKGDVILKYSADEARSLKAYGELP Sphar GGKNRRRGKNKRELIFKEDGQEYAQVVKMLGSGRLEAMCFDGTSRLCHIRGKLRKKVWIAQGDIILIGLRDYQDAKADVIVKYNADEARNLKAYGELP Spipu1 GGKNRKRGKNKRELVFKEDGQEYATVTKMLGNGWVEAQCCDGEKRLAHIRGAFRKKVWITQGDLVLLGLRDYQDSKADVILKYTPDEARMLKSYGELP Sporo1 -------------------------------------------------------------------------------------------------- Stehi1 GGKNRRRGKNKRELVFREDGQEYAQVTKMLGNGRLEATCFDGEKRLAHIRGKMRKKVWINQGDIVLLSLRDFQDDKADVIVKYTADEARNLKAYGELP Tapde11 GGKNRRRGKNKRELVFAEDGQIYAQVTKMLGNGRLEAACFDGEKRLAHIRGKLRKKVWINQGDIILLSLRDYQDEKGDVILKYTADEARNLKAYGELP Thetr -------------------------------------------------------------------------------------------------- Treme1 GGKNRRRGKNKRELIFKEDGQEYAQVVKMLGNGRLEAKCQDGETRLAQIRGQMRKKIWIVAGDIILLSLREFQDGRADVIHRYTPDEARNLKNYGELK Trire2 GGKNRRRGTKRRELTFKEDGQEYAQVVKMLGNGRLEAMCFDGSKRLANIRGKMRKKVWINQGDIILLSLRDFQDGKGDVILKYTADEARNLKNLGELP Umbra1 -------------------------------------------------------------------------------------------------- Ustma22 GGKNRRRGKNKRELVLKDEGQEYAQVLKMLGNGRLEAQCFDGEKRLAHIRGKLRKKVWINQGDIILISLRDFQDGKADVIQKYNADEARALKQQGELP Walse1 ----------------------------MLGNGRLEASCFDGVKRLGHIRGKMRKKVWVGAGDIVLLSLREFEDEKADIIHKYSPDEARALKQYGELP Zygro1 GGKKGRRGKNKRELIYKEDGQEYAQITKMLGNGRVEATCFDGVKRMAHIRGKLRKRVWMGQGDIILVSLRDFQDDQCDVIHKYNLDEARTLKNQGELP [Cluster2098.fasta_al_trimmed; alignment length = 187] Allma1 CFISHITDPFLNLAVEEVLLLWRNTPTVVIGRNQQWKECNIPWVRRKSGGGTVYHDLGNSIYSIIEPRESFTRAELVTRALH-LD-VVNDRHDIVVGSAFKLTSRRAYHHGTMLIDA-NLTSLRKYLTKGVPSVPSP-VTNLVDHTGFCEAVVDEFLEELTSDEWRLGQTPEFTHEIVHCRGGQVTA Ashgo11 ILRSTSTDPYFNLALEDRLLFYTNDKSVVIGKNQPWKELYYEYVRRKSGGGAVVHDLGNVNYSYLTSRERFDRNKQLVRWL--VQ--LNERGDITLGSAFKIGKGKAYHHGTMLVSS-DLAQFSGLLCRSVESVRSQ-VQNLDTIDEFCQVVVSGYAEELKSFQWKFMSSPKFTVHLILVEKGIVIQ Aspfu1 IYQSLSSDPYVNLSIEHILFLYVNRPCVVIGRNQPWLETNVLLVRRRSGGGAVFHDFGNLNYSVISPRTTFTRAEMVVQALN-IG-AVNDRHDIVMGSAFKLTRHRALHHGTCLLDSPNINDLGFFLAKGVDSVRSP-VTNVFSIQAVMEGIMEQFIDELRSLEWKYTQTPQFTFSTLRFKHGAIVE Aurde31 ILVSKSMAPFLNLALEDSLLVYRNEPSVIIGRNQPWKEVNIWLARRRSGGGTVYHDAGNSNYSIHLPRTSFDRGRVVERAVDILG-VMNARNDLVVGSAYKIAGKRAYHHGTMLLES-ALEDLGEVLTKGVESVRAP-VTKLATHDNFVNAMVQSFLAFWQSWDWIYGQTPEFTHSLIHSKHGVVLD Batde5 VFVSKVTDPWINLAFEDQLMLYRNVSSVIVGRNQPWRECSIPIIRRKSGGGT---DMGNTNYSIMMPRDEFDRAHLVSRALQ-MD-VVNARHDIVIGSAFKLVNHRAYHHGTMLIST-DISKLGAYLGRGVESVKSQ-VTSLADHDGFCKCVAQEFYHTLKSWEWTFGETSQFVHTIITVLEGIITD Botbo1 VYVSASDCPYHNLAFEDLLFIYRNAPSVIIGRNQPWKEINIPFVRRKSGGGTVYHDLGNTNYSVSVPRESFDRAELVAAAVA-LG-PVNERHDICVGSAYKIIGRRAYHHGTMLISA-KLDQLGDLLTKGVESVRSP-VRNLIAHEAFVGATVREFIEELQSWEWSHGQTPEFTHVLMHSKHGLILD Botci1 ---------------------------------------------------------------------------MVVRALK-LG-VVNARHDIVLGSAYKLTRERSLHHGTCLLNSPNISNIGKFLARGVESVSSS-VANVIQNKAFEKAVVEEFLEEL-----------------FTARNGAIIE Caeel VLKSTSSCIFENLAYEEILLMWSNRPAVVIGRHQPWIEVNIQIVRRHSGGGTVYHDLGNLNISLLTTHAQHCRLKFISDALQQFS-VPNKRDDMELGTAARIARGQAYHHLTLLVGA-DLQVLSKSLSNATRSVRAPAVGFLANVEQSKLAIVEAYLK---AWKWIYGKSPKFQYSRIEVKDGLVLD Canalb1 IFVSKLTNPYMNLAIEDRLMFYINTPCVVIGKNQPWQEVNVPMLRRRSGGGTVVHDLGNVNYSYMTTKANFDRASYIVEAVK-IE--TNERGDIVSGSAYKLSKGKSYHHGTMLLNS-KLDVLGKLLKMSIPSVKSK-VINLKS-DKFIDVVSQKFADELKQWSWRFGHTPKFTHSFFNVEKGC-LK Cangl VLRSISHNPYFNLALEDRLVFYINNKCAVIGKNQIWEELHYEVLRRLSGGGAVLHDLGNVNYSYICSRDEFDTNGRIVSWLP-VS--LNQRGDILSGSAYKVALGKAYHHGTMLIKS-NLSDFKGLLTNSVVSVRSP-IENLPSPDTFIDLCTSQFMQKLQSNDWKYHSGPKFKVHIIAVEKGFIVD Capow VYISTSTNPWWNLALEEQLFLYRNSPCVVIGRSQPWKECNIAFLRRKSGGGTVFHDEQNLNLSFLTNRTSFNKSLFVARTLSRLG-ILTPRNDVFLGSAYRLVSRSAYHHCTLLVAT-ELSSLRQSLTRAIDSVRSP-VTSLVTVEAVCDVISQQFCEELQSWDWTFGQTPVFTQTLVKCNDARIVD Catan2 AYRSLSTNPYLNLAIEEILLLWRNSPCV----------CNIPWLRRKSGGGTVFHDLGNSIYSIIEPRETFTRAELVAR--------VNERHDLVVGSAFKLTN----------------TPVAQVLHKGRSKCSFA-SHQSVDHGSFCEAVVDQFYEELMSDDWKLGQTPEFVNEIVSSRQGRITA Cioin VYTTSVTDPFYNLAFEECLFIWRSQPSVVIGRHQPWKECRINLCRRSSGGGAVYHDLGNLNFTFFNEKSEYNTLKLITRGLETWPFLVNRRDDI-IGTAARLGRRSCYHHCTLLVST-NKSNLTKYLSIATDSVRST-VRNLINCKNVSNAVTQVYAKELLQWEWVYGKTPKFTY--LEVKEGIVSN CocheC53 SYISTSSDPYLNLSIEDILFLYVNRPCVVIGRNQPWSEVNVDLVRRRSGGGTVFHDEGNLNWSITCPRADFTRAEMVVRALK-LG-VVNERHDIVLGSAYKLTRQRALHHATTLLSSPNLHIIPHYLTRGVESVSSP-VANILDVKTFQLRLQEEFYDELQSEEWMWSQTPAFSLMLIQVHHGAIKS Coere1 CYVSQSTDPYTNLAFEDVLYLWRNRPTVVIGRNQPWKECNVWLARRTSGGGAVYHDLGNTNYTVVMPRDAFTRAQMVAQALH-AD-IVTARHDVAVGSAFKLTGSRAFHHGTMLIDA-DLTRLNGCLARGVDSVRSP-VANLIDHATFCEAVRRQFRTRIGAWDWLYGQTPDFVHRFISARRGRITA Conco1 IFVSNLTSPHWNLSIEEIGYFYRNEPCVVIGRNQPFKECNITLIRRNSGGGAVYHDYGNSNYCIMVPREEFKRSKLVSDTLK-LG-CLTPRNDIAVGSAYKIAGEKAYHHGTMLLGS-DLSKLMKYLSKGIESVRSN-VINLLDHKLFWGSVAKSFYNKLKSWDWTYGQTPEFKQKILICKNSIIKE Conpu1 IYVSLSNDPYFNLSFEDLLLLYRDTPCVIIGRNQPWTEVNIPFIRRRSGGGT---DLGNTNFSIHVPRTTFDRAQIVLRAVA-LG-IVNTRNDITVGSAYKIANNRAYHHGTMLIST-RLDTLGALLTKGVASVRSP-VCNLTTHDAFVQAVVDEFMEELPSWDWAYGQTPEFTHDLISSKHGRIIS Copci IFVSTSTDPYFNLTLEDLLLIYRDTPCVVIGRNQPWKEVNIPFIRRRSGGGTVFHDLGNSNYSIHLPRTSFDRAQVVVRAIQ-LG-V-NDRNDICV-SAYKIVNNRAYHHGTMLIST-RLDTLGDLLTKGVASVRSP-VCNLITHEDFTNVVINEFMEELKSWEWQFGQTPEFTYDLLRSKHGVVLD Croqu1 -----------N---KGKLLIYRNSKSVIIGRNQPWTEAKVPLIRRWSGGGTVYHDEGNTNYSIMIPRGMFDRGELVVRALS-IG-LLNQRHDICLGSAYKLTRERAYHHGTMLINS-DLTSLHELLSKATDSVRSP-VTNLLTHSAFAEALAQAFMKELQSWEWTFGQTPEFSHMLIHVRHGKINA CryneH991 TYISKSHDPWFNLSYEDVLFLYRNFPCVVIGRNQPWKETTIPLVRRRSGGGTVYHDMGNTNFSIILPRLLFTRAQLVSRAIK-LG-IVNDRNDVVI-SAYKIIQHRAYHHGTMLISS-SLAELGKSLTKGIASYRSP-VTTLLHHDDFVRAVTAEFYEELKSWEWQYGQTPEFTNELIAARHAVITS Crypa2 VYTSRTHDPYLNLSAEHVLFLYANDPCVVIGRNQPWLELNVALVRRRSGGGAVFHDRGNVNYSVICPPAQFDRAEMVVRALR-LG-VVNARHDIVIGSAYKLTRLRSLHHGTCLLSSPNLRDIGRLLARGVESVRSR-IRNVIGSEEFVEAVMGEFYEELTSREWIYNQTPLFTFST---------- Debha1 IFVSKLKDPYLNLAIEDRLMFYKNWPCAVIGKNQPWKEVNIPLVRRRSGGGTVVHDLGNVNYSFMTTKPKFDRAEIIRDSVK-LK--VSERGDITTGSAYKLSKGKSYHHGTMLLDL-KLDVLGKLLMASINSVKSK-VINLKD-EKFIELVSDGFADELKEWKWKYGSTPKFSHELFHVKKGAIID Dekbr2 VFISRFRDPRINLSIERRLVSYRNAPCIVIGKNQPYKEINIPILRRYSGGGTVCHDLGNVNFSFMAGKSLFNRTNILIKALSEFPKFTNAKGDMVNGSAYQLSKGRYLHHGTMLLNA-DLHAMSGLLDKSIKSIPSP-IQNIMDPELFEYCCVNSFYKTFKSWNWVFGRTPKFKLHFLHVHEGRIVE Dicdi IYKSTTNNALFNIATEDTLYLWRNSPTVVIGRYQPYKECHVVLARRYSGGGAVYHDLGNTNFTFLSPTADYSKTNIIINSLS-IG-IASGRNDIIVGSAYKQSGPRSFHHGTIMINV-NLDSLQKYLSKGITSVISR-VLNMMNHEMVCDSVIKEFYETLQKWDWRYGNSPEFEHQFMNVTKSIIDK Dmel VFISQSSDVFTNLALEDVLLLWANDPCVVIGRHQPFTEANITLARRNSGGGAVYHDLGNLNCTFFSPRERYDRLNIVTRALREWA-IINERDDIVVGTAAKLGHPNSYHHCTILASA-NKLHLGESLSKATASVPSP-IRNLVNVAQLRSAVGYEYRSNYSSWDWVIGKTPKFTVQKVEVEAGLMKE Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VFYLESTDPFLNLATEEVLMFYQNRPCIVVGRNQLWTELNIALVRRRSGGGSVFHDLGNTNWSLVSHRTIFDKANIIAGALR-LDVVTSARQDVLVGAAYSIIRDRALHHATMLLSA-DLNMLRGTLSRGVKSVSSP-VRNLLQAMDFSKAVVEELYEELRSWDWFHGQNPNFEQAILKSERGLIVG Fomme1 IYISKSTNPYFNLTLEDLLLLYRDEPCVVIGRNQPWKEVNVPFIRRRSGGGTVYHDLGNTNYSVHLPRTSFNRAQLVVRAVS-LG-V-NDRNDVCAGSAYKIASNRAYHHGTMLIST-QLNTLGDLLTKGVASVRSP-VQNLITHEGFVNAAVRSFMEELKSWDWLYGQTPEFTYTVITSKHGLILS Fusgr1 VYTSKSRDPFLNLSVEHILFLYTNDPCIVFGRNQPWMEVNVQLVRRRSGGGAVFHDEGNVNFSVICPPAVFDRAEMVVRALS-LG-KVNERHDIVMGSAYKLTRLRSLHHGTCLLRSPNLKNISGMLTRGVDSVRSP-VRNVIENAAFEGAVLEEFYDELQSRDWIYGQTPRFTFSSFDARHGVVEK Galma1 IYVSASSDPYFNLTFEDLLFIYRDSPCVVIGRNQPWTEVNTPFLRRRSGGGTVYHDLGNTNFSIHLPRTSFDRGRLVLRAVS-LG-I-NERNDICVGSAYKIVNKRAYHHGTMLIST-ELDTLGDVLTKGVGSVRSP-VCNLLTHEQFTAAVVKQFMAELSTWDWAFGQTPEFTHTLIRSKHGVISN Ganpr1 CYLSTLTDPWKNLAIEEVLLLWRNSKCVVLGKNQPWKEINVPLVRRRSGGGTVYHDLGNTNYSLMVPRTEFSRATMVARALN-LD-ITNERFDVVVGSAYKIVSQRAYHHGTMLINS-DLADLRKYLSKGIGSVPSP-VTSIASHQAFCHQVRNEFVKETKEWEWTYGLTPQFLHELLHSTEGVITQ Gloin1 CFISKSMDPWTNIAFEEILFLWRNNSCAVIGRNQPWKECNIPLIRRKSGGGTVFHDIGNTNYTLIMPRIDFTRAELVVRALR-LD-IVTERHDIAVGSAFKLVMRRAYHHGTMLIDT-DLDRIKRYLTKGVESFPSP-VTNLVSHESFCEAVKDYFREEFKTWEWVYGQTPDFTHKFFESKNGIITA Hisca1 -----------------------------MARNQSWAPEH------------------NLNYCVICPKPVFHRAEMVVRALR-VG-AVNERHDIVLGSAYKLTRFRALHHGTCLIDSPNLGNITSFLAKGVDSVRSP-VGNVFLMDQVISNIMEEFVSAIHALALTNTHAPA-----LRVKSGAIIS Klula1 VIRSVSTNPYFNLALEDRILLYTNDKCVVVGKNQPWKETYYNFVRRRSGGGAVVHDLGNVNYSYLTSRESFRRNQQLVQWL--IT--LNDRGDLIYGSAFKIAKGKAYHHGTMLIDS-DLAQFKGLLCNSVESVRSK-VDNISSIDDFCNLITDQFSENLRSKEWKFMSGPRFEVICIKVEKGVIIE Lacbi2 IYISNSTNPYFNLTLEDLLLIYRDEPCVVIGRNQPWKEVNVPFLRRRSGGGTVYHDLGNTNFSIHLPRTSFDRGQIVLRAVS-LG-VLNERNDICVGSAYKIVNKRAYHHGTMLIST-RLDTLGDLLTKGVASVRSP-VCNLVTHEAFTAAVVNEFMAELPTWDWAYGQTPEFTYTIIRAKHGVILD Lenti61 IYISNCTDPYFNLTFEDLLLLYRDEPCVVVGRNQPWKEVNIPFIRRHSGGGTVYHDLGNTNFSIHLPRGSFDRAQVVLRAVS-LG-I-NDRNDICV-SAYKIVKDRAYHHGTMLIST-RLDTLGELLTRGVASVRSP-VCNLVSHEDFVEAVVDAFMSELKTWDWTFGQTPEFTYDVLRSKHGILLQ Malgl1 -----------------ACFLYVNEPCIVVGRNQLWNEVDVPVVRRLSGGGAVYHDSGNMNFSFHTSKTNFVRTDLITRALSRFG-RRTERNDLAVGSAYKLANRRAYHHGTLLLAA-DLQRMSMLKSKAVASVPSP-VANLLTWPNLVDAIHAEFYEEMRGWDWLYGSSPPFTVRVLSCVHGIIEH Mellp23 -------------------MIYRNTKSVIIGRNQPWTEANVPILRRRSGGGTVYHDEGNTNYSIMIPRGMFDRGELVTRSLS-LG-LLNHRHDICLGSAYKLTRDRSYHHGTMLINS-NLSQLKDFLSRATDSVRSP-VTNLLDHTSFTNSLTRTFMKELQSWDWTFGQTPEFSNTILNIRQGKIHN Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 TYISKINDPYTNLAFEEILFLYRNSKSVIVGRNQPFKECNIPFVRRKSGGGTVYHDMGNTNYSIMMPREVFDRVELICRALE-LD-IVNERHDIVV-SAFKLIQHRAYHHGTMLIDT-DLSSLGQYLTKGVASVRSP-VTRLIDHLSFCEATRTEFRDEMKTWGWMYGQTPEFSYQLIKSKEGLITQ Mucci2 CYISTIHDAYTNLAIEEILYLWRNKPCVVVGRNQPFQECNIPLVRRRSGGGAVYHDMGNSIYTIFMPREAFSRAQLVARSLQ-LD-IVNERHDIVVGSAYKITSTRAYHHGTMLIDA-ETETLKGCLSKGVESVPSP-VTNLVDHQQFCESVLAEFRQELKTWDWIYGQTPEFTNTIILSRHGKILK Mydma IWLSLSNCVYENISFEEILFIWRNTPSVVIGRHQPWKEVNIKLCRRNSGGGAVYHDLGNVNFTVFSNRELYNRLNFVVEFFEVYK-IINHKDDI-IGSAAKVGLNNAYHHFTLLCNA-NVNCLSEVLTSATQSVSSP-IKNLFDFADFVKNLTEFYLK---AWDWTYGKSPKFSVD-IVVQKGLISE Neucr2 VYQSTSKDPYLNLSIEHVLFLYINDPCVVIGRNQPWLEVNIKLVRRRSGGGTVFHDHGNVNWSVICPPAVFDRAEMVVRALD-LG-VVNERHDIVIGSAYKLTRLRSLHHGTCLLNSPRLKNIGKFLARGVESVRSP-IRNVVDTEEFTKGVVDEFMDELTSIPWIYGQTPQFTFSSFTLRHGEIQT Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 IYQSLSTDPYVNLSIEHILFLYANRPCVVIGRNQPWLETDAVFVRRRSGGGAVFHDEGNLNYSVICPRTSFTRAEMVVRALQ-VG-AVNERHDIVMGSAFKLTRFRALHHGTCLLDSPNIHDLGRYLAKGVESVRSP-VGNVFSMQSVVESVIEQFIAELRSLEWKYTQTPRFTFSTLRLQHGAIVE Phybl2 CYISTINNCYTNLAIEEVLYLWRNKPCVVIGRNQPFQECNIPLVRRRSGGGAVYHDMGNSIYTIYMPRHAFSRADLVSRALQ-LD-VVNDRHDIVVGSAYKIINQRAYHHGTMLIDA-DTEALKGCLSKGVESVPSP-VTNIVDHQQFCESVLAEFAKELQTWDWMYGQTPEFTNTIIHSKHGMITD Picst3 VFQSKLTSPYLNLAIELRLMFYVNSPCVVIGKNQPWKEVNIPLVRRKSGGGTVVHDLGNINYSFMTTKEKFDRAHLVRDAVQ-LE--VNDRGDITTGSAYKLSRGKSYHHGTMLLNL-RLDVLGKLLSNVINSVKSK-VSNLES-DKFVEVVSSGFAEELKTWAWRFGSTPKFTHELFFVGKNAKVE Plicr1 IYLSDSTNPLFNLSLEDLLLIYRDDPCVVIGRNQPWKEVNIPFVRRRSGGGTVYHDLGNTNFSIHLPRAAFDRAQVALRAVS-LD-I-NDRNDICVGSAYKIVNRRAYHHGTMLIST-QLDTLGDLLTKGVASVRSP-VCNLVNHDAFTKAVIDAFMAELPSWEWAYGQTPEFVYTLIRSKHGIILS Polpo VYKSTTDDALFNIATEDTLFLWRNGPTCIIGRHQPFKECHVTLARRYSGGGAVYQDHGNSIYTLLSPTTQYDKTAIVIDSLQ-FG-ISSGRNDVIV--------------------------------KGISSVVSR-VCNLITHERWCESMIESFYDGLSNWEWRFGATPEFDHQFINSNRGVIND Pucgr2 -----------NETIKRILFIYRNRKSVIIGRNQPWQESNISLVRRRSGGGTVYHDEGNTNYSVMLPRDQFERARLVAKAVD-MG-IVTDRYDVCVGSAFRITNKRAYHHGTMLISS-NLAQLKGALSKAVGSVRSP-VTSLINHLRFVHNLSLAFYDELKSWNWIYGQTPQFTRLF---------- Punst1 IYVSESSNPYFNLTLEDLLLLYRDEPCVVIGRNQPWKEINIPFIRRRSGGGTVYHDMGNTNFSIHLPRSSFDRSQVILNAVS-LG-I-NARNDLCVGSAYKIVNNRAYHHGTMLLTT-RLDTLGDLLTKGVASVRSP-VCNLIDHSMFVNAVIKSFMEELRTWDWAYGQTPEFTYSLIHSKHGIILD Rhior3 --------------------------------------------------------MGNSIYTIFMPREAFSRAELVARSLQ-LD-IVNERHDIVVGSAYKITNARAYHHGTMLIDA-DTETLKNCLSKGVASVPSP-VTNLIDHQQFCESVLSEFRRELKTWDWIYGQTPEFTNSALLVRHGKIIK Rhoto1 IYVSDSHNPWFNLAFEDILYMYRNDPSVIIGRNQPWKEIDIPFVRRKSGGGTVYHDLGNTNYCVFVPRLEFDRAELVTNGLK-LD-LVNDRNDICVGSAFKLVNKRAYHHGTMLIDA-QLGNLRGVLTKGVASVPSP-VRNLIEHEKFVEVVAREFVAELKSWEWQYGQTPEFTHEIISSRHGLITS Rozal11 IIVSKCTNPFINLGYEETFLLYRNRTCLVVGRNQIWQECNVPILRRYSGGGTVYHDLGNSCYSWIRPRQDFDRSKLLADTLDALN-VVNSRFDVVYGSAFRITNNSSYHHGTLLRNS-DLSQLRSCLTKAIHSVPSP-CINIFRHDDFVQHVIKKL--ELHSWKWVWGRTPEFKQIILTVKQCEIID Sacce1 VIQSLSTSPYYNLALENRLLFYINDRCAVIGKNQLWQEVDFELLRRFSGGGTVLHDLGNVNYSYLTSREKFETNKMIIKWLR-LD--LNERGDIIQGSAYKIAGGKAYHHATMLLNA-DLEQFSGLLSSGVHSVKSK-IKNVITPNQFIAVVSERFMNTLQSEQWKYFSGPKFSVKIIKVEKGMIYD Salro CYNISSTDVYSNLAFETAMLFWRNDPCVVIGSHQPWIECNVHLARRRSGGGTVYHDAGNLNVTFMTSRAKHNPSGVIAAVIKAYG-LRPKRSDIFVGSAFRLKTQAAYHHCTLLIDS-DPQAISHYLSRGIESVRSP-VTTLLQHRSRSVDLPSLI--------WR-----QLGHEL---------- Schco3 IYLSESTDPYFNLTIEDLLFLYRNTPCVVLGRNQPWKEINIPFIRRRSGGGTVYHDLGNTNYSIHVPRTWFDRSQIVLRAVG-MG-VVNERNDVCVGSAYKIVSSRAYHHGTMLIST-QLQTLGSLLTKGVASVRSP-VCNLLSHEAFADSMVREFMEELPSWEWAYGQTPEFEYTVIRSKRGLITG Schpo1 VVVCKSVNPYFNLALENLL-LYTNSPSVIIGRNQPWVEANVNIIRRKSGGGTVFHDFGNLNYSVLMNREEFSHASIMIQALN-LG-VLNQRHDIVLGSAYKISRNRCYHHGTMLLNS-DLEGVREYLSKGVSSTRSP-VSNTLLKAEFIKQVISCFVNELQSWEWTFGQTPSFKQHLISVVHGRLEK Sorma VYQSTSNDPYLNLSIEHVLFLYINDPCVVIG---------IKLVRRRSGGGTVFHDHGNVNWSVICPPAVFDRAEMVVRALD-LG-VVNERHDIVIGSAYKLTRLRSLHHGTCLLNSPQLKNIGKFLARGVESVRSP-IRNVVDTQEFNKRVVDEFMDELTSIPWIYGQTPQFTFSSFTLRHGEIQT Sphar VYRSTSIDPYANLALEDVLLFWVDEPSVVIGRNQPWTECDVHFVRRKSGGGTVYHDSGNLNISLVTGRDAYTKTRVIATALK-LG-VVNDRNDLAIGSAYKLGGRCAYHHCTLLTTT-DIKSVGKYLSRGVSSVRSP-VSALLTIDAVIDSITRELRDTLVGWDWQYGQTPQFTQQVLSCKRGVVES Spipu1 CYISKETDPWINLAFEEILYLWRNQTCVVIGRNQPWKECHVPLVRRRSGGGAVYHDIGNSNYTIFMPRDEFDRAQLVCRGLQ-LD-IVNERHDLVIGSAYKLVNARAYHHGTMLIDA-DLTALGRYLGKGVESVRSN-VTRLVDHLSFCEAVAGEFYDEIRTWEWIYGQTPDFAHRLMNVHRGMITE Sporo1 IYVSESNDPHFNLAFEDILYLYRNTPSVIIGRNQPWKEINIPFVRRKSGGGTVYHDLGNTNYCVFVPRLEFNRAELVARALQ-LK-IVNERNDICVGSAFKLVNHRAYHHGTMLIDA-QLSHLRGVLTKGVASVPSP-VRNLLDHERFVELVAKEFMEELRSWEWQYGQSPEFTHELIRSRHGLITA Stehi1 SYISQTTNPYFNLAFEDVLFVYQDDPCVVIGRNQPWKEINILFVRRRSGGGTVYHDLGNVNFSIHVPREVFDRGEIVIRALS-LN-I-NERNDISIGSAYKIVKDRAYHHGTMLISS-KLEDLGGVLTRGVASVPSP-VTNLITPRQFTEAVVDAFILELGSWNWMFGQTPEFTYSLFNSKHGDILS Tapde11 ----------------------------------------------------------------MMKRDKFDRAQKIINGLAGLD-VLNERHDITIGSAYKISKDRAYAHGTMLLAS-DLGNLGPALGNGVESVRSK-VANLLTHEEFCAILAKAFRAQLISDHWKYSQTPVFTQTI---TTGAYTI Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 AYISTSTDPWFNLSYEDMLFLYRNVPCVVIGRNQPWKETTIPLIRRRSGGGTVYHDMGNTNFSIFLPRLLFTRAELIARAIR-IG-VVNSRNDIVIGSAYKIIQHRAYHHGTMLISS-DTSLLGKALTKGIPSYRSP-VTTLITHENFVSAVIEEFIEEMKSWEWEFGQNPEFSNILLSARHARLT- Trire2 IHLSRSTDALLNLSVEHVLTLYVNSPSIVFGRNQPWLQVNIQLVRRRSGGGAVFHDGGNVNFSVICPPEQFDRAEMVVRALA-LS-RVNERHDIVMGSAYKLTRLRSLHHGTCLLRSPNLSSISELLARGVDSVRSP-VRNVVDNDEFKDAVVREFYEELGSKSWTWGQTPRFTFST---------- Umbra1 CFISTHTDPFVNLAIEDILYLWRNKPCVVVGRNQPFKECNIPLVRRRSGGGTVYHDMGNSIYTIFMPRTAFTRAELVARALQ-LD-IINSRHDIAVGSAYKLTNQRAYHHGTMLIDT-DVDKLRGALTKGVASVPSP-VTNLIDHQQFCEAVIEEFRDELTSWDWIYGQTPEFTHDFIRSRHGRVTE Ustma22 AYVSLSTNPWFNLAFEDICFLYRNSPCVVVGRNQPWKELNLPMVRRRSGGGTVYHDLGNTNYSFHIPRDDFDRAELVARALR-SD-VVNGRNDICIGSAYKLVNKRAYHHGTMLLSA-SLRSLGSSLTKGVASVPAP-VANLLSHEMFVQAVVAEFFDELQSWDWVFGQTPEFTHRVIHSKEGVVLD Walse1 AYVSHSKDPWFNLAFEDVLFLYRNTPSVIIGRNQPWNEMDIPFIRRRSGGGTVFHDLGNTNYSVMMPQSVFNRAQLVASALK-LD-VVNERHDIVVGSAFKLTSSRAYHHGTMLLNS-NIKTLSQALTKGVPSVRSP-VKNVITHETFVDAIIKRFKDELQEWSWHYGQTPEFTNTVIKSKHGRITE Zygro1 VLQSLSTDPYYNLALEDRLLFYKNDNCVVIGKNQVWKEVFYEFIRRLSGGGAVVHDLGNVNYSFITSRKEFDRNKLIVKWLA-LH--LNSRGDITLGSAFKIAKGKAYHHGTMLIHS-NLQNFKGLLCNSVDSVRSK-VTNMKSAQEFIDTCVAGFMSKLKSDEWKYLSGPNFRVNIISVQKGIIVD [Cluster2104.fasta_al_trimmed; alignment length = 164] Allma1 ALA-NLNLRLDKLRGPRIMVVGPRDSGKTTILKTLANYAVKLFVDLNPDNPSVSISGTMAAMPVPLIFWYGYDQSVARQIARAVDRKCEAGCLVDTQLAATDQLLVVQAFP-RVPGALKYAHIHRIREYFYGLTPHNIAIPPTTMTVVRHSVLALRNVIGFVYV Ashgo11 LY--NLHFALEKMRGPRILVVGKASSGKTSLCKILCSYALKIYVNLNPQEGAFSPPGFLTATPIPMVKNFGLEMEVLGQLAQTVDGRLKSGVIVDSSLAVE--LSDIVRIP-TSRGIRRALQRSQIREYFYGLSPYTIGVDLLDAVVWRHALVAISGVLGVALI Aspfu1 YA--NVHFALEAMRGPRVLILGPENAGKTSVAKILTAYATKIVVNLDPAEGMLSVPGTLTATAFPLVYFYPLQNPIVSRLALSVTGRMATGIIVDTRLYST--MMKVVKLS-KSGGCMKSVRESQIRTYFFGLSPHAQQLDFDSLAVYNNSLLAVASIMGFLYV Aurde31 CA--NLHILFEKMRPPRLLVLGQENSGKTSVCKILSNYAVRLVVNLDPGEGAWTVPGTLSACPIPLVHWFGHTEHLIRRLAASVDTRLGSGVIIDAKLYVE--MQRVIKIP-KSGGARERVHSYQMRAYMYGLAPHSSSISFDDLKLFRNAVLALRDVAGFLVV Batde5 YL--NVHLALEGMRGPRVIIVGQADSGKTALAKLLINFAAKVFVDLDPSQGTVSLPGTLSAMVVPLVYYHGQATSIVKKLSLVVDKKLESGLIADTRLYSD--LFRVVKLN-KSGGVRRKMQMQRVKEYFYGMMPFSQTVPFSEVVVRRHSILALSNVAGFIYI Botbo1 YI--NLHLAFEQSRPPRVMFLGPENSGKTSAMKILANYAVRMIVNADPNEGGWTVPGTISACPIPLVFWYGHADRLLADLGEAVRVRFKAGLFLDTKLSVE--MQRVLKIP-KSGGVRQRVHAYQQRAYFYGLSPYSSVVGFDDITIYRNALLALLDVVGFVLV Botci1 YI--NTHFALENLRGPRVLIVGPNNTGKTSLAKLLTAYAVRIVVNTDSREGMLSIPGSLTAAAFPLCYYYGLPSPVVTRLALAATSRLQTGMIIDTRLHSE--MLRLVRLD-KSGGCMQQMREATIKEYFFGLSPHTQVVNFDELSIYKHCIFAVASVMGFVYV Caeel -----------------------------------------------------------------------------------------------------------------------------------------------------HHLFAFSPVFGFCLV Canalb1 IL--NLHMYLESKRGPKVLIIGSKYSGKTTVSKILSAYANKVLVNLQPRDGVFALPGSLTATPIPIVKNFGMADLLIEKLGIAVLSRLDSGVIIDTRLAIE--LTKIIKLN-KSSGCIRLQQEQTIKEYFNGLSPFKTDIELSGLKIYKNSIVAITSVLGYIHV Cangl VY--NLHFALEKMRGPRIMVVGEKNTGKTALCRTLCSYAIKMFVNLNPVEPIFSPPGCVTAVPIPIIKNFGFETLVTKKLFETVSERLQSGCIVDSEIYTK--VSKL-RVP-TMAGVIRAQQRAAIREYFYGLSPYNLGCDTSDITVWRYALVAIAPILGFGLI Capow YV--NTHAALEQLRGPRVLIAGAGDVGKSSLCKILLSYAARLYVDLDVGQGSISVPGVMATALVPLLYHFGHLSSIMGRIATAVTRRCQSGVIINTRLHHD--IATVVSLP-KSGGVRRKTRNERVKQYFYGLFPSRTTIKLNDFVFVRYTVLSVTNVLGFVFV Catan2 MVA-NMHVALEQARGPRVMIVGEPDTGKSTVAKTLANYIHKLLVDLNPENPTISIPGTLSLIHLPLILWHGSDQRVCKEAARACDDKVAAGVVVDAYLSAT--LPTLIHLS-PVPGVRKYLHLHSIREYFYGLTPHNIAVPTSIISVVKHSILAVANVMGFVYV Cioin YL--NTHAAVEQLRGPRVLVVGAQDVGKTTVCRLLLNYAVRTLIDIDVGQGGVSIPGSVGALTVPLVYHFGHTATLISRLADVFNAKCDSGCIINTRLYND--LKRVILQP-KSPGVRRDNRENKIKEYFYGYFPHAFNIKFSEVEIYKHHILSLTNVAGFVVV CocheC53 VA--NLHFALENLRGPRVLVVGPENSGKTSLVKTLTSYAVKMVVNLDPRQGMLSVPGSFSAAAFPLVYHYGLRDPLVTRMALAVTSRLEAGFIIDSRLYSD--LSRVIRLD-KSGGCMRALRHAQIKEYFFGLAPSSQTADAADLHIFRNQLLAISSVRGYVYV Coere1 YI--NVHVALQQQRGPRVMIVGPEDCGKTALARILLTYAARLFVDLDPRDASVSVPGTLSVAAVPLVWQFGYEQALVDCAASAVTRRQKSGLIVDTRMHSV--LAAVLKIP-RSGGARQQLGARAVQRYFYGVTSFSTVVPFDDLCILRHSVLAVLQVVGFVNV Conco1 YL--NLHLSLEGLRGPRVLLVGPNDSGKTSLAKILLHYGVRLYIDLDSTEGSAVVTGSLSVTSIPLVYYHGFESLQIDQLAKAVQRRVDSGCVIDTRLYSE--ILKTLKLP-KSGGVRRKVLMNHVKQYFYGLTPFSNVVSFNNVEIYRHSVLAVSNILGFIYV Conpu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci YA--NVHTALEQMRAPRVLVLGPENSGKTTVCKILINYAVRMLANVDPSEGAWVIPGTLSVASVPLVSWYGHTDRLIRNLGENVNDRFDSGLIVDTKLNVE--MQRVVKIP-KSGGVRERVQRYQLQTYMYGLSPSSTVMKFGDLSIYRGAVLALLSVIGFVYV Croqu1 YL--ALHLALERIRGPRVMIIGPISSGKSTLVKTLANWAVRLLVNLCCNDGAFTLPGTFSIAPLALSFYYGHPDVLIRRMGVSLESRVEGGCLIDTKLQLE--ISKVVRVP-KSGGAQRRLQSNQVRSYFYGLSPFKIVVKFEDLTIYRHMVLSIGPVLGFVHL CryneH991 LL--NLHLAMERQRGPRVMIMGPQSSGKTTVMKNLVNLALGGVIGLDPSSPPNLIPGSLSISTPTASWWLGALEVLVEHMAEAWGMRCESGLFLDTKLHID--LSRVIRIP-KSGGARETAHLFQVRTYFYGLSPYSFQIPWSRLVVLRNRVLALREVMGFIVM Crypa2 HM--NLHVLLDRLRGPRVMIVGPNSVGKTTMARTLTAYAVKIVVNMNPREGMLPLPGTLTAATFPLVYYYGREHEVASKLAGAVTSRMSAGLIIDTAGSEA--LRKVVSLDEKPDGVLLACQHAAIKEYFYGLSAPKQMVDFDSVTIYRHWTMPVASVQGFVYI Debha1 YM--NLHFALESYRGPRVLVVGNRHSGKTSLVKTLASYGCKILVNLNPRDGVFSVPGSLTATPIPLVKNYGFTSYQISKLGVAVVSRMESGLLIDTRLLID--LKKFVKVP-KSGGVIRKSQEESIKEYFNGLSPFKTELDAKDFVIYKNSIVAITCVLGYAHV Dekbr2 LL--NLHLALENIRGPRVLVIGPKNSGKTSLCRVIASYAEKLYVNINPQEPVFTTPGNLTATAIPLVKNFGLENYLIGQMSGCIEKRLESGIIVDTRLLVD--LKRLLKVA-KSSGC----------------------------------------------- Dicdi YA--GVYQELDAFRGPRVIIVGPTDSGKSSLSKILLAYSARLFVDLDPGQGSITIPGTISAAHIPLAHFYGHTSALCKNLASFIDKQLDSGFIANTKLYSD--ISSIIKLP-KSGGVRKKTRMNRIKEYFNGLSPHYIVLDFKDVSIYRHSIFAISNVAGFLYV Dmel YV--NCHAALEQFRGPVAMVVGPMDVGKSTLCRILLNYAVRLYADLDVGQGSIAISGSVATILIPLVYHFGHKSAVVSKMAEVTLQSLNSGIIINTRLYNE--LLRVVLLP-KSGGVRHEARDQRIKEYFYGFYPFSFEVKFQDLRLYKHHVLALTNVAGFCCV Enthi YY--SIFNNLNDNRAQIILVTGPARSGKTTFALHQLNYQVQLFVDLSLSTNIITLPGCIGCTVVPLVYCCGTTKHYIELLAANCLTKMNSGMIIRCQLLNE--IESSSFVN-KPAGIIRRLQHRAVNNYFYGLCPRSSVLLSSSAKVVTNDVYALTNVIGFVTV Falba YLSDDVHFALSAMNPPRVVILGPADSGKTALALTLCNYGSRLLVDLDLELNTLTVPGAIAAMPVSLSYYFGHTTRLVDNLAGRVRARTQNMVVINTRLYNR--LQRIVRLP-RSAGARRILQNAVIARYFLGYGMRHAYVPFDNIRVFKQAILGVTPAMGFVHV Fomme1 YM--NLHLAFEQMRPPRVLVVGPENAGKTTACKILANYAVRMFVNVDPGEGGWTVPGTISACPIPLVYWYGHAERLIRNLGENVTSRQDSGIIVDTKLNVE--MQRVIKLP-KSGGVRERVHRYQIHNYMYGLSPLSTTIPFSDLTIYRNSVLALLAVVAFLVV Fusgr1 HM--NLHGQLNDMRGPRALIVGPADVGKTTLARTLTSYATRLVVNANPREGLLSLPGTLSASVLPLVFYYGQTSELTSKLAGSVSARLSSGVIIDGAISSE--LSRVVPID-KSDGVLQHVREAAIKEYFYGLSPLIQQVDFDNVVVYHHWTLAVASVMGFLYV Galma1 YA--NLHIALEQMRPPRILVVGPDHSGKTSLCKILTNYAVRFLVNVDPSEGGWAAPGAISVAPVPLVYWYGYPERLIRNLGENVYDRFESGLIVDTKLNVE--MQRVVKIP-KSGGVRERVHNYALHTYMYGLSPSSTVINFGDLQIYRNAVLALLTVVGFLIV Ganpr1 YL--NAHLALELVRGPRVLIVGPSDSGKTSLTKILLNYAIKLFVDIDPGEGTVTVPGSLSATPLPFVVYHGYPRAQVGRLAEVVEKKVASGFIINSRLYSE--LSRVVKLA-KSGGVRKQLEHRAVREYFYGISAYSTPIVFTEMNVRRNSVLALAAVAGFAVV Gloin1 YL--NMHIALEQCRGPKVMIVGPEDVGKTSLSKLLLSYAIRLFINLDSNEGSITMPGTLTATPIPMVFYYGYPDVLTKKLADNVSRRLVSGIVIDTRLYSD--MARVVKLS-KSGGVRRQAQMRKIREYFYGLSPCSTLINLNDISIYRHSILAISTVIGFIYV Hisca1 YV--NIHGALETMRGPRVLILGAEDAGKTSLAKILTGYATKVVVNLDPSEGMLSVPGSLTATAFPLVYFYGLPSSFV-------------------RLYSS--MVKVVKVT-KSGGCMKSVRDSQIRSYFFGLSPHAQQLDFDSLSIFTNTLLAIASIMGFVYV Klula1 IY--NLNFALERLRGPRVLIVGNASTGKSSLAQMLCSYALKLLVNLNPQDGVFSLPGSITATPIPLVKNYGLENSTITQLASGVQQRLKSGVIIDTDLAIE--LSEIVRIP-PPGSIRRALQRVQIREYFYGLSPYTMGAGFEELTVFRHAIIAIASIIGYGLI Lacbi2 YA--NLHIAFEQMRPPRVLVLGPENSGKTTVCKILTNYAVRLLVNVDPSEGAWSAPGALSIAPVPVVYWYGHPDRLIRNLGENVNDRFESGVIVDTKLNVE--MQRVVKIP-KSGGVRERVHNYQLHTYMYGLSPSSSVIKFEDLSIFRNAVLALLTVSGFLIV Lenti61 YG--NVHMALEAMRAPRVLVLGPETSGKTSVCKILTNYAVRVFVNVDPSEGGWAVPGAISAAPIPLSYWYGHAERLIRNLGENIRDKYESGLVVDTKLNVE--MQRVLKIP-KSGGVRERVHKYQLHTYFYGLSPLSTTVNFGDITIYRNAVLAILHVVGYIVI Malgl1 CT--NLHLNLERARGPRVMIVGPESAGKTSLIKFLANYALRMIVALDPSEGAVPVPGCVSAIPLPISLWMGKENRVIDWLAYYIEKRLVSGLLLDMKLNLE--LTRIVKVP-RSGGAKQKLHDLQIRSYFYGLSPYSTTIPLDLLSIYRHSVLALAAILGFVHV Mellp23 HL--ALHLALERMRGPRVMVVGGLSSGKSTLVKTLANLAIRLL-------GAFTLPGTFSIAPLALSFYYGHADALFRRMGSALDARIEGGLIVDTKLQLE--MSKVVRVP-KSSGAQRRLQSSQIRSYFYGLSPFTIVVKFEDLMIYRHMVLAIGPVLGFVHL Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr YL--NTHMALEQRRGPRVLVTGPSGSGRTSLCRILLNYAVRLFVDLNPREGNLAVPGTLGAAVIPHVLHFGHAGHQVASLARIVSSKMESGMFINCRLVNE--LNAIIGLP-KSGGVSKGQDHAAFYKYFYGLSPFSFDVKLGKVQVFRHRICSVSSVLGCVCI Morel2 YL--NTHIALEQRRGPRVLIVGPNDVGKTSLSKMLLSYALRIYVDLDCSEGSITMPGCLTATPLPLAYYYGFPSLLLARLAQSVNRRLESGIVIDTRLYAD--MTRVIKLA-KSGGVRRQTQNQKIREYFYGLAPYSTMINFHDIEILQHSVLAVTNLAGFIYV Mucci2 YL--NTHLALEQLRGPRVLVVGPHDVGKTSLCKILVSYSLKIYVSLDTTEGSITMPGTVTATCIPLAYYYGFENMVSSCLASAIRSRMASGFIIDTRLYSD--MNRVVKLS-KSGGVKTRLQRAKIHEYFYGLSPYSMLVNYDDIKVWRHSILAISNVAGFVYV Mydma YL--NVHMALEQMRGPKVVICGPVNVGKSTLSRILLNYGVRIFVDLDVGQGSIAVPGSMGALLVPLVYNFGHTTALVSQLADVVFKHFESGFIINTRVYND--FKTCVHLP-KSGGVRSHARDERIREYFYGLYPHVFDVKFDEIKVYMHSLCAVSNVAGFIVI Neucr2 YI--NLHFGLQDHEGPRVLICGPPGVGKTSLAKLLAALATRLVANLNPTDGLLCLPGTLGAAVFPLTFYFGHEKQMTERLAVLARRKFEAGLLVDTQLKTE--LGQVLGLD-KSDGARQKSTETAIKEYFFGLSPFTQSASFDELVVFKHWTLAVSSVLGFIVI Orpsp11 YL--NTHMAIEQLRGPRVMIVGPPDVGKTTLSKILINYAVKMFVDINPNEGTVTIPSTLTATVIPLTYFFGYLQKLLTKLSITIQKKMDSGLIISTRLYSD--ISKVVKLS-KSGGVRRILQSYKIKEYFYGLAPYSVIVPFTDIFIRTNSILALTKLLGFVH- Pench1 YA--NVHFALETMRGPRVLLLGPENTGKTSLAKILTAYATKLVVNLDPTEGMLGVPGTLTATAFPLVYSYPMQSPVVSRLALSVTGRMATGVIVDTRLYST--VAKVVKLS-KSGGCRKATRESQIRSYFFGLSPHAQQLDFASLPVYNNTLLAVASIMGFLYV Phybl2 YF--NAHMAIQQMRGPRVLVIGPHDVGKTSLCKTLVSYALRIYVSLDTSEGSITMPGTVTATCIPLAYYYGYENLIVSRLANAVKSRMSSGYIIDTRLYSD--MTRIAKLT-KSGGVKSQLQRSKIQEYFYGLSPYSMLVNFSDISIWRHSIMAVCNVAGFIYI Picst3 YI--NLHLVVEAMRGPRVLIVGNGNSGKTSLAKLLSAYAIKVLVNLNPRDGVFSLPGSLTATPIPIVKNYGFVDYQVSKLGVTVLSRLEGGVIIDTRLMID--LKKIVKVP-KSEGLIRRTQEESIKEYFNGLSPFKTDIDVNDHTIYKNSILAITSILGYVHV Plicr1 YA--NLHIALEQMRPPRVLVLGPENSGKTSVCKILANYAIRLLVNVDPSEGGWAAPGAISAAPVPLVYWYGHSDRLIRNLGDNVNDKYDSGLIVDTKLNVE--MQRVVKIP-KSGGVRERVQNYQLHTYMYGLSPSSTIISFDDLSIFRNAVLALLNVTGFLVI Polpo YA--NIHSIMDQHRGPRVLIAGPTDVGKSTLAKILMGYSARAFIDLDPGQGSITLPGALCASLIPFVQYYGHTSAQIQSLGISVDKRMESGMIVNTKLYSD--LSRVMKLP-KSGGVRKQTRMQRIREYFYGLCPHITIVDFKDVCIFRHSVLAISNVAGFLYV Pucgr2 YM--ALHLALERARGPHVMVIGSLASGKSTLIKTLANWAVKLLVNLNPNDGGWTVPGTFSVAPLALSFFYGHTQVLIKRVGSALETRIEGGLLIDTKLHLE--ISKVVRVP-KNGGARRRLESNQIRSYFYGLSPFTIVVKFEDLTIYRNLVLSIGPSLGFIHL Punst1 YA--NLHFAFEQMRPPRVLVLGPENSGKTSLCKILANYCLRILVNTNTSEGGWGVPGTVSAVPLPLTYWYGHANRIIRNLGENINDRWDAGIIVDTKLNVE--MQRVVKVP-KSGGVRDRIQAYQLHAYMYGLSPSSTVISFGDLQIYRNSVLALLHVVGFLVV Rhior3 YL--NTHLALEQFRGPRVLVIGPHDVGKTSLCKILASYSLKIYVSLDTSEGSITMPGAVTATSIPLAYYYGFESLVTSKLADAVKSRMAAGIVIDT----------IIKLS-KSGGVKNLLQRTKVHEYFYGLSPYSMLINYDDVKIWRHSILAISNVVGFIYI Rhoto1 YF--NLHLSLSRLRPPRVLVVGERGAGKSTLVKMLANWRNRTLVNLDPSDGLWTVPGTIGIVNTPLVFFAGHLSLLMQSVADAAKRKVDAGWMVDTRSYVE--MSKVVRVP-KSDGALSRLQSLQTRSYFYGLSPFSIIVRLSDIRIVRNRILAVGPVMGFVWV Rozal11 YY--NLHLALEQRRSPRILLIG---SGRNTASKILANYAVRLYIDLD---GSTLFPGTMNAFVLPLSYFYGQTSKIIAKMATVLYKKLEARMIIIARLYSE--IIKVLKVP-KSGGVRRQEMSRQINRYFYKFTPYSLILNYKDVSVKKHMILALSNVFGYMCV Sacce1 IY--NLHFMLEKIRGPRVVIVGGSQTGKTSLSRTLCSYALKLYINLDPQQPIFTVPGCISATPIPMVKNFGLERECISQLGQVVGQRLHSGCIVDTPLWEK--VKKIFFIP-KLDGVKRSLQRTSIREYFYGLSPYAIGVDYEDLTIWKHAIIAISPILGFALI Salro ML--NLHAALENQRGPRIMVVGPDFSGKSSCCRILANYACRILVDVDPNDNFFGMPCCVAAAPVPVFFHFGHTTKAVERLGKTVQAKLSSGVVVNCRLVNE--LKRILKIP-KSGGVKLRRTQERIRQYFYGFMPHSVSIPFSRLRLFKRHVVSVSALCGFVVI Schco3 YA--NLHIALEQMRPPRVLILGPENSGKTSLCKMLVNYASRVVANLDPAEGAFALPGAISAAAIPLVYWYGHPDRLVRNLGMGVSDREDSGFIVDTKLSIE--MQRVVKIP-KSGGVRERIHEYQMHTYFYGLSPSSTVIGFGDLSIYRNALLAVLTVSGFIAV Schpo1 YL--NLHFALEGLRGPCVCLIGPRSCGKTSVLKILESYALKICVNLDPTQPMLALPGSISAFHNPLVYNFGLDSLSLSRLALAVHSRMSSGCLVDTRLYSS--MKRVVKVS-SSGGCIQQFQARCIKQYFYGLSPLSMIVDSTQLVVYRNSILAVSCIIGYVFV Sorma YI--NLHFGLEDYEGPRVLVCGPHCVGKTSLVKYLGALATRLVANLNPTDGLLSLPGTLSAAVFPLAFYFGREKQMTERLAVLCKRKLEAGFLVDTKLKTE--LGQVLGFD-KSDGARQKSTETAIKEYFFGLSPFTQSASFDELVVFKHWTLAVSSVLGFIVI Sphar YI--NTHAALEQRRGPRCMIVGAADVGKSRVSQTLINYAVRLLVDLDCGQGAVTVPGTISAALFPLCYHYGCTTYIVEALAKGLDERCLAGYIINTRLYSE--LSRLVRLS-KSGGVRHDERSAQIRQYFYGLFPHSLVVPFDSVKVFKHSLLSVYSVQGFVYV Spipu1 YL--NVHLALEQLRGPKVMIVGPEDVGKTSLCKILLNYAVKIFVDIDPNEGSVSLPGTLSATAIPLVYYYGYASALVERLAGVVNKKLDSGCIINTRLYSE--LTKIIKLA-KSGGVRKQLQMHKIKEYFYGLSPYSSLVSFTDVAVRMHSILAVTNLAGFVYV Sporo1 YL--NLHLSLSRLRPPRVLVIGERGAGKSSLIKMLTNWRNRTVVNLDPNDGAWTVPGTLGVVSTPLVYYYGHLALLLKSIAGAVKRKVDSGYLIDTRLYVE--MSKVVRVP-KSDGALSRIQASQIRSYFYGLSPFSIIVKFDDVRICRNRLLAVGPVGGFVWV Stehi1 YA--NVHIALESLRPPRVLIMGPENSGKTSVCKILTNYAVRLLVNTDPGEGGWSVPGTISAASVPLVYWYGHEGRLIRNLGENVTARQEAGIIVDTKLNVE--MQRVVKIP-KSGGVRHRIHAYQIYNYMYGLSPSSSIIGFDDLTIYRNAVLALLHVVGFLAV Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr YA--NVHGALQTLRGPVVVVAGPTDVGKSSLCKILVNFAIRLFVDLDVGQGGITVPGMLGALILPLVYFYGHASRMLDKVAGEARELFAAGAVINTRLTQE--LTSVVKLA-KSGGVRRSARSSKMKDYFYGLAPAATTIYFRDVQIYRSCILAVANIAGFLHV Treme1 IL--SLHLALEQRRGPRVMLVGPTSSGKTTVAKNLVNLALSCVVGLDPSSPANLIPGSISLSLPTVGWWYGHTEKLVSAMGERWKERCASGLIMDTKLTID--LLRVLRLP-KSGGVRELVHAFQVRCYFYGLTPYSFQIGWETLIVLRNTVLAIREVLGFVVI Trire2 HI--NLHARLSDMRGPRVLVVGPPNSGKTTLVKTLTSYATRITVNADPREGMLSLAGTLSASVFPMVFHYGRESELVARLAGAVSGRLSSGVIVDSKIHAD--LTTVVALD-KSDGVLQHSREAVIKEYFFGLSPQIQQVDFDALTIYKHWTFAVASVLGFVYV Umbra1 YL--NLHLALEQIRGPRVLVLGPHDVGKTSLCKILLSYALRLHVSLDCSEGSITMPGTMTATSIPLAYYYGYQNLLTSKLAQGVKARSAGGQIIDTRLYSD--MTRVVKVA-KSGGVRTQLQRSKIHEYFYGLSPYSTLTNFADVSIWRHSVLAVSNVAGFIYV Ustma22 YS--NLHLYLERKRGPRVMILGPESAGKTSLVKLLANYALRVVVNLDPSDGAPPLPCCLSALPLPLSLWLGKENRVVDWLAEGVERRFASGLIIDTKLNLE--MTKVIKLP-KSGGVRSRLKALQVKTYFYGLSPYSTTIPFDLLEIYKHSVLALAPILGFVHV Walse1 YL--NLHLAFEQQRGYRVMVIGQEDSGKSTLSKTLLNYTARILVNLDPSDGGPLPPGTISATAYPQALPYAHASSIVEAIARRLDMRLESGVFIDTKLYIE--MQRVLKVP-KSGGARSRVQAGQIKSFFYGLSPQSMTIKIDNLKVFRHSLLYLADLVGFLIV Zygro1 VY--NLHFALEKMRGPRVIVIGSSGSGKTALCRTLCSYAIKMFINVNPQEGIFSPPGCVTAVPIPFVKNFGLERKMVNELALVVDDRLASGCIIDTEIFEK--YSAI-RVP-KLSGCKRLLQRSAIREYFYGLSPYAIGADIGDVNVWKHSLVAIAPILGFALI [Cluster2109.fasta_al_trimmed; alignment length = 236] Allma1 WKIDAFFTEESSFATLFPKYREAYLREVWPHVTRALCELDLIEGSMTVRTTRKAFDPYAILNARDLIKLLSRSVPFQQAVKILDDNVACDIIKIGNIVRNKERFVKRRQRLVGPNGNTLKAIELLTECYILVQGNTVSVMGSHKGLKTVRRIVLDCLANIHPIYHIKELMIRRELAKDPQLAKENWDRFLPKFRKPEAKPLFPPAQTPRQVDLQLESGEYFLQKAADEAEFVAPEE Ashgo11 WAIEEFFAEESSFMTLFPKYRETYLKSIWKEVTRALCELNLVEGSMSVKTTRKTYDPAIILKARDLIKLLARSVPLPQAIKILQDDIACDVIKIGNIVASKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPYKGLKEVRRVVEDCMRNIHPIYHIKELMIKRELAKRPELAEEDWSRFLPMFKKKVYTP-FPPAQLPRKVDLEIETGEYFLARRAQQAEYIAPAE Aspfu1 WKIEEFFAEESSFATLFPKYREQYLKEAWPVVTRALCTLDLVEGSMTVKTTRKTFDPAAILKARDLIKLLSRSVPVQQALKILEDGVACDIIKIRNQVRNKERFVKRRQRLLGPSGSTLKALELLTSTYILVQGNTVAAMGPYKGLKEVRRVVNDCMANIHPIYHIKELMIKRELAKDPTLANESWDRFLPNFKKKVYTP-FPPAPEKSKVDLQIESGEYFLEVMERQRQFIPPEE Aurde31 WKIDPFFVRESSFATLFPRYREKYLREIWGTATRALCTLDLVQGSMSVKTTPKTYDPYVLFKARDMIKLLARGVAINQALRVLEDGVACDIIKIGGMVRNKERFVKRRQRIIGPDGSTLKAIELLTECYVLVQGNTVSVLGPHKKLKEVRRIVEDCMKNIHPIYRIKELMIKRELAKDPKLATESWDRFLPQFRKKVYTP-FPPPQQPRKVDLQLESGEYFLERRKKQEEFVAPEE Batde5 WKVDEFFLAESSFATLFPKYRETYLREVWPMITASLCALDLVEGSITVKTTRKTYDPYIILKARDMIRLLSRSVQFNQAVKILEDGVACDIIKIGGLVRNKERFVKRRQRLLGPKGSTLKAIELLTNCYVLVQGNTVAAMGPFKGLKDVRRLILDCMKNIHPIYHIKELMIKRELAKDEKLKEESWDRFLPKFKKKERTP-FPPPQQPRKIDLQIESGEFFLKKKEKQDAFIAPAE Botbo1 WHVAPFFTEESSFATLFPKYREKYLREAWGAVTRALCSLDLIHGSMSVRTTRKTYDPYIIVKARDMIKLLARGVAAGQAVKILDDAVACDIIKIGNLVRNKERFVKRRQRIIGPDGSTLKAIELLTGCYILVQGNTVSVMGPFKALKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLANESWDRFLPQFRKKVYTP-FPPAQLPSKIDLQIESGEYFLKRKQKQNEFVAPVE Botci1 WKIEAFFTEESSFATLFPKYREVYLKTVWPLIMKSLATLDLREGSMTVKTTRKTYDPAAILNARDLIKLLARSVPAPQAIKILEDGVACDVIKIRNLVRNKERFVKRRQRILGPNGSTLKALELLTECYLLVQGNTVSAMGPYKGLKEIRRIIEDCMANIHPIYHIKELMIKRELAKDPELAGESWDRFLPQFKKKVYTP-FPPAQEKSKVDLQIESGEYFLERIEKQREFEAPAE Caeel WDINTFLLQESSFSSLFPKYREKYIKESWPLIEKALADLDLLEGTMCVRTTRKTWDPYIIMKAREVIKLLSRSVPYEQAIRVLEDEIYCEIIKISSMVRNKERFVKRRARLIGNDGATLKALELLTQCYVCVQGGTVCAVGPLAGLKQINQIVTDCMKNIHPIYNIKTMMIKRELSKNDELKDANWDAYLPNYRKKEFTP-FPPAPVMSKIDKQIESGEYFIAKLEASAVYQAKEE Canalb1 WALEEFFAEESSFMTLFPKYREQYLRSIWSDVTKALCELDLVEGSMTVKTTTKTFDPAMIIKARDLIKLLARSVPFPQAVKILQDDIACDVIKIGNFVANKDRFIKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYYIKELMIKQELSKNPALANEDWSRFLPSFKKKVYTP-FPPAQQPRKIDLQIESGEYFLEKRSKQEEFEAPEE Cangl WKIEEFFAEESSFMTLFPKYREAYLKSIWNDVTRALCTLDLVEGSMTVKTTRKTFDPAIILKARDLIKLLARSVPFPQAVKILQDDIACDVIKIGNTVANKDRFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPYKGLKEIRRVVLDCMKNVHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKKVYTP-FPPAQLPRKVDLQIESGEYFLEQREKQAEYIAPKE Capow WKIETFLLEESSFATLFPKYREKYLKEVWPHVTKALCELDLIEGSMTVRTTKKTFDPFIILKARDLIKLLARSVPLAQALKILEDDVVCDIIKIGNIVRNKERFVKRRQRLLGPNGATLKAIELLTDCYVMVQGNTVAAMGGYKGLKEVRRIVEDCLHNVHPIYNIKTLMIKRELAKDPALATESWDRFLPQFKKK--TP-FPPLPQPSKIDLQLESGEYFLEREERQAEFEAPAE Catan2 WKIESFFLEESSFATLFPKYRETYLREVWPHVTKALCELNLIEGSMTVATTRKTYDPYIILKARDLIKLLARSVPFPQAVKILEDGQAMDIVKIGNIVRNKQRFVKRRQRLIGPNGNTLKAIELLTGCYVLVQGNTVSVMGEHKGLKAVRRIVIDCINNIHPIYHIKELMIKRELARDPKLKEENWDRFLPKFRKEEEKPLFPPAQLPRKIDLQLESGEYFLAKAEAAVEFVAPEE Cioin WKEPEFMLDESSFATLFPKYREKYLQECWTIVKNKLGILDLIEGSMTVKTSRRTWDPYAILNARDLIKMLARSVPIEQAVRIFEDNTFCDIIKIGSMVRNRERFVKRRQRLVGPNGATLKALELLTGCYILVQGNTTTVLGSHAGLKEARKVILDTMKNIHPVYNIKSLMIKRELSKDPNLKNESWDRFLPKFKRKPYTP-FPPPQPESKVDKEIASGEYFLERKEKQGVLIPPQE CocheC53 WKIEPFFTDESRFSTLFPKYREQYLKGSWKFITQALCELNLVEGSMTVWTTQKTYDPAAILNARDLIKLLARSVPAPQAIKILEDDVAMDIIKIRNLVGNKERFVKRRQRILGPNGSTLKALELLTECYLLVQGNTVACMGPYKGLKQVRRIIEDTMHNIHPIYAIKELMIKKELAKDPELANESWDRFLPNFKKKPYTP-FPPPQEKSKVDLQIESGEYFLEREEKMKEYVAPEE Coere1 -KALTFLLEESSFATLFPKYREGYLREVWPLVTKALCKLDLVEGSMTVSTTRKTWDPYYILKARDMIKLLSRSVPFPQAMKILDDDMACDIIKIGNLVQNKERFVKRRQRLLGPNGNTLKAVELLTECYVMIQGSTVSAMGSLKNLSLVHRIVEDCMKNIHPIYHIKELMIRKELAKDPKLANESWDRFLPRFKKKEL---FPPAPTPSKIDLQLKSGEYFLRRKQASMEFVAPKE Conco1 WKIDQFFLEESSFVVLFPKYREAYLRDIWPHLTALLCVLDLIEGCMTVKTTRKTFDPAMILKSRDLLKLLSRSVPFNQASKILQDDMACDILKIGGITRNKERFVKRRQRLIGPNGNTLKALELLTGCYIMVQGNTVSCMGPFAGLKKLRAIILDCMKNVHPIYHIKELMIKRELEKDDKLKSENWDRFLPKFRKKEYNP-FPPEQPKRKIDLEIESGEYFLKKKQNEFEFEAPEE Conpu1 WKVDPFLTEESSFATLFPKYREKYLREVWSAVTRALCTLDLVHGSMSVRTTRKTFDPYVILKARDLVKLLARGVAINQAVKVLQDDVACDIIKIGSLVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGSTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLATESWDRFLPQFRKKTYTP-FPPAQMPRKVDLQLESGEYFLKRKQKQNEFVAPVE Copci WKIEPFFAEESSFATLFPKYREKYLREVWSAVTKALCTLDLVHGSMSVRTTRKTYDPYIILKARDMIKLMARGVALNQAVKILQDDMACDIIKIGNLVRNKERFVKRRQRIIGPDGSTLKAIELLTNCYVLVQGSTVSVMGPFKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLATESWDRFLPQFRKKVYTP-FPPPQLPRKVDLQLESGEYFLKRKQKQMEFVAPAE Croqu1 WKIEPFFTEESSFATLFPKYREVYLREIWSHLTKVLCVLDLVEGSMTVKTTRKTFDPFIILKARDLIKLLARSVPITQAVKILEDDVACDVVKIGNIIRNKERFVKRRQRILGPSGSTLKAIELLTGCYILVQGTTVSVMGPYKGLKTVRKIVIDCMKNIHPVYHIKELMIKRELAKDPKLANENWDRFLPNFSQKKYTP-FPPPQLPSKIDQQLESGEYFLKRKEGQDAFLPPEE CryneH991 WALEEFFLEESSFALLFPKYREPYLRSVWSSITSALCELDLVQGKMTVKTTRKTWDPYIVFKGRDLLKLLARGVNAPQAIKILEDGIACDIIKIGGIVRNKERFVKRRQRIVGPNGSTLKAIELLTECYVLVQGNTVSVMGSYKGLKEVRRIILDCMNNIHPIYRIKELMIRRELAKDPKLANENWDRFLPKFQKKVYTP-FPPPQQPSKLDLQLASGEYFLKKMEKQKEFVAPPE Crypa2 WEIPVFFAEESTFTVLFPKYREVYLKEAWPLVTRSLCTLDLVEGMMTVKTTRKTFDPAAILNARDLIKLLARSVPAPQAVNILEDGVACDIIKIRNLVGNKEKFAKRRQRILGPNGSTLKALELLTETYILVHGNTVSVMGPYKSLKEVRRVVEDCMHNVHPIYLIKELMIKRELAKDPELAGESWDRFLPHFKKKTYTA-FPPAPEKSKVDLQIESGEYFLEREDKARQFVPPEE Debha1 WSIEEFFTEESSFMTLFPKYREQYLRTIWSDVTRNLCQLDLVEGSMTVKTTRKTFDPAIILKARDLIKLLARSVPFPQAVKILQDDIACDVIKIGNFVTNKDRFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMNNVHPIYYIKELMIKQELAKNPELAHEDWSRFLPMFRKKVYTP-FPPAQLPRKVDLQIESGEYFLEKRDKQEEFEAPEE Dekbr2 WKIEPFFLEESSFKTLFPKYREEYLKQIWGDVTKALCTLDLVEGSMTVKTTRKTYDPVQILNARDLIKLLARSVPFPQAVKIMQDDVACEVVKIDGLVSNKERFIKRRQRLIGPSGNTLKALELLTDCYMLVQGSTVSIMGPHQGLKVLRRVIIDCMKNVHPIYHIKELMIKRELAKRPDLANEDWSRFLPQFKKKVYTP-FPPAQTPRKIDLEIESGEYFLEAKEKQSEYVAPEE Dicdi WKPLELLYDDSSFATLFPKYREKYLQEIWKLVENVLCKLDLIEGSMTVTTTKKCWDPVAILKARDLIKLLSRSVPFEHAQKVLNDDYNCDIIKIGGFVRNKERFVKRRQRLVGPDGSTLKAIELLTKCYVLVQGNTVSSIGPWNGLVQVRKIVEDCLKNIHPIYNIKELMIKRELEKDETLKNENWERYLPQFKKRDAAP-FAPPQLPRKEDLAMESGEYFADREAKHAEQIAPAE Dmel MKIPAFMVEESSFATLFPKYRERYLKEVWPLVEQCLAELDLMEGSMVVKTSRKTWDPYIIIKARDMIKLMARSVPFEQAKRVLQDDIGCDIIKIGNLVHKKEKFVKRRQRLIGPNGATLKSIELLTDCYVLVQGNTVSALGPYKGLQQVRDIVLETMNNVHPIYNIKALMIKRELMKDPRLANEDWSRFLPKFKNKEYTP-FPPSQPESKVDKQLASGEYFLERTEKQKEFVPPTE Enthi WKVNDFLLEESSFSILFPKYRESYLKGMWYVINKALGELDLVKGIMTVKTTRKTWDPFIIIKARDMLKLLSRGVPAQEAIKVLQDQYWCDIIKIGNMIKNKERFVKRRQRLVGPNGATQKAIEILTGCFILIQGKTVSVIGSPSGIKMVRKIVEDCMDNIHPIYNIKALMIKKELMKNENMKNEDWSRYIPQYSKKNYSP-FPP-------------------------------- Falba WKPVTIFLEESSFATLFPKYREKYLKEIWPEVTRALCVLDLIEGSMTVKTTRKAFDPFILFKARDLIKLLARSVPFVQAVRILEDDMACDIIKIGNIVRNKERFVKRRQRLIGPDGNTLKAVELLTQCYILVQGNTVSCMGPFKGLKVVRRVILDCMNNIHPIYHIKELMIKRELEKDETLKNENWDRFLPKFKKKEYTP-FPVPQQPSKVDLAIESGEYFMRRLATQAEFEAPAE Fomme1 WKIDPFFLEESSFATLFPKYREKYLREVWSAVTKALCTLDLIHGSMAVRTTRKTFDPYIILKARDMIKLLARGVALGQAVKILNDDMACDIIKIGGLVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGNTVSAMGPYKSLKEVRRIVLDCMRNIHPIYRIKELMIKRELAKDPKLANESWDRFLPKFRKKVYTP-FPPPQQPRKVDLQLESGEYFLKRKEKQAEFVAPTE Fusgr1 WRIEPFFTEESSFATLFPKYRESYLKEVWPLITRALCSLDLIEGSMVVKTSLRTHDPSSILKARDLIKLLARSVPAPQAIKILEDGIACDIIKIRNQVASKERFVKRRQRLLGPNGTTLKALELLTKTYILVHGNTVSVMGPYKGLKEIRRVVEDCMANIHPIYHIKEAMIKQELAKDPELANESWDRFLPNFKRKVYTP-FPPAPEKSKVDKQIESGEYFLERREKQNKFIAPEE Galma1 WKVDPFFREESSFATLFPKYREKYLREVWSAVTRALCTLDLIHGSMSVRTTRKTFDPYVILKARDVIKLMARGVAVNQAVKVLQDDTACDIIKIGGLVRNKERFVKRRQRIIGPDGSTLKAIELLTNCYVLVQGNTVSVMGPFKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLASESWDRFLPQFRKKVYTP-FPPAQLPRKVDLQLESGEYFLKRKQKQEEFVAPVE Ganpr1 WKIDPFFAEESSFAVLFPKYREQYLRQVWPLVTKALCVLDLIEGSMTVKTTRKTFDPYIIFKARDLIKLLSRSVTFQQAQRILEDGLACDIIKIGNIIRNKERFVKRRQRLIGPNGNTLKAIELLTSCYVMVQGNTVSAIGPYKGLKEVRRIVIDCMRNIHPVYYIKELMIKRELAKDPKLANESWDRFLPKXKKSEYTP-FPPPQTPRKIDLQLESGEYFLRKKEKQAVFEKPEE Gloin1 WKIEPFFTEESSFATLFPKYRENYLKEVWSHVTKAL---------YDSKTTRKTYDPYVIMKARDLIKLLARSVPFPQAVKILEDGVACDIIKIGNIIGNKERFVKRRQRLIGPNGSTLKAIELLTQCYVMVQGNTVSAMGSYKGLKEVRRIVIDCIKNIHPIYHIKELMIKKELSKDPKLKNESWDRFLPHFKKNEYTP-FPPAQTPSKVDLQLESGEYFLKKKERQKEFVPPVE Hisca1 MVIEEFFTEESSFVSLFPKYREAYLKETWPMITKALCTLDLVEGSMTVKTTRKTFDPASILNARDLIKLLARSVPAPQALKILQDDVACDIIKIRNLVRNKERFVKRRQRILGPSGSTLKALELLTNTYILVQGNTVSAMGPYKGLKEIRRVVEDCMNNIHPIYHIKEMMIKKELAKDPKLANESWDRFLPHFKKKVYTP-FPPPQEKSKVDLQIESGEYFLEIIERQKEFVPPKE Klula1 WNIEEFFAEESSFMTLFPKYREAYLKSVWKDVTRSLCELNLVEGSMTVKTTRKTYDPAVILKARDLIKLLARSVPFPQAVKILEDDVACDVIKIGNFVSNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSVMGPYKGLKEVRRVVEDCMKNVHPIYHIKELMIKRELAKKPELAEEDWSRFLPMFKKKIYTP-FPPAQLPRKVDLEIESGEYFLERREQQAAFIAPKE Lacbi2 WKVDPFFTEESSFATLFPKYREKYLREVWSAVTRALCTLDLVHGSMSVKTTRKTYDPYIILKARDMIKLLARGVAVSQAVKILDDAVACDIIKIGTLVRNKERFVKRRQRIIGPDGSTLKAIELLTNCYVLVQGSTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLATESWDRFLPQFRKKVYTP-FPPAQQPRKVDLQLESGEYFLKRKQKQAEFIAPVE Lenti61 WKIDPFFTEESSFATLFPKYREKYLREVWSAVTQALCTLDLIHGSMSVRTTRKTYDPYIILKARDMIKLLARGVAIGQAVKILNDDVACDIIKIGNVVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGSTVSVMGPYKGLKEVRRIVLDCMKNIHPIYRIKELMIKRELAKDPALATESWDRFLPKFRKKVYTP-FPPPQQPRKVDLQLESGEYFLKRKEKQEEFVAPEE Malgl1 WKIERFFLEESSFATLFPKYREKYLREVWGHVTTALCTLDLVEGSMSVRTTRKTFDPYIILRARDLIKLLSRSVPFTQAVKILQDDMACDVIKIGNIVRNKERFVKRRQRIIGPNGNTLKAIELLTGCYVLVQGNTVSAMGSYKGLKEVRRIILDCMKNIHPIYHIKELMIKRELAKDPKLANESWDRFLPKFKKKIYTP-FPPPQQPSKLDLQLESGEYFLKKLQAQAEFMAPEE Mellp23 WKIEPFFTEESSFATLFPKYREVYLREIWSHLTKVLCVLDLVEGSMTVKTTRKTCDPFIILKARDLIKLLARSVPITQAVKILEDGVACDVVKIGNIIRNKERFVKRRQRILGPSGSTLKAIELLTGCYILVQGTTVSVMGPYRGLKTVRRIVIDCMKNIHPVYHIKELMIKRELAKDPKLVNENWDRFLPNFSQKKYTP-FPPPQLPSKIDQQLESGEYFLKRKEGQEAFNPPME Mnele WKMEEFLLEESSFATLFPKYREKYLQQVWPNVVSCLALLDLIEGSMTVKTTRKTWDPYMIVKARDMIKLLARSVPFEQAKRVLQDEMTSDIIKIGNVTRNKERFVKRRQRLVGPNGNTLKALELLTECYIKVQGSTVAALGPYKGIKQVRNIVMDTMNNIHPIYNIKILMTKRELMKDPALKNESWDRFLPKFKKKKYTP-FPPPQQPSKVDLQLESGEYFMEKEQAQQQFAAPKE Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 WKVEEFFTEESSFATLFPKYRENYLKEVWGHVTRALCVLDLVEGSMTVKTTRKTYDPYMILKARDLIKLLARSVPLPQALKILEDGIASDIVKIGNIVRNKERFVKRRQRLLGPNGSTLKAMELLTQCYIMVQGNTVSAMGPYKGLKEVRRIIIDCMNNIHPIYHIKELMIKRELAKDPKLAEENWERFLPHFKKKDYTP-FPPAQTPSKIDLQLESGEYFMRKKEEQKEYVPPVE Mucci2 WKIEEFFTEESSFATLFPKYREAYLKETWPLVTAALCVLDLVEGSMTVKTTRKSYDPYSILKARDLIKLLARSVPFPQAVKVMEDGIACDIIKIGNITRNKERFVKRRQRLIGPNGSTLKAIELLTKCYMMVQGNTVSAMGPYKGLKDLRRIVLDCMKNIHPIYHIKELMIKRELAKDPKLATESWDRFLPHFKKKEYTP-FPPVQTKSKIDLQLESGEYFL-------------- Mydma WKVEPFLIEESSFATLFPKYRETYLREVWPLVKEKLCALDVVEGSMTVATTRKTFDPYIILKARDMIKLMSRGVSYEQSCRVLEDDVACDIIKIRNLVRNKERFIKRRQRLIGPNGATLKALELLTECYILVQGGTVSAIGSFKGLKQVRNVVEETMKNIHPIYNIKIMMIKRELAKDPTLKNENWSRFLPKFKNKPYTP-FPPPQQESKIDIQLASGEYFLNKKKKQEEFIPPSE Neucr2 WKVDPFFLEESSFMTLFPKYRERYLRDSWPLITKALAVLDLVEGSMTVKTTRKTYDPAAILNARDLIKLLARSVPAPQAIKILEDGMACDIIKIRSMVRNKERFVKRRQRILGQNGTTLKALELLTQTYILVHGNTVSVMGPFKGLKEVRRVVEDTMNNVHPIYMIKELMIKRELAKDPALAHEDWSRYLPNFKKKNYTP-FPPAPEKSKVDLQIESGEYFLERAEKAKQYVPPEE Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 WKIEEFFAEESSFMTLFPKYREQYLKEAWPVITRALCTLDLVEGSMTVKTTRKTYDPAAIIKARDLIKLLARSVPVTQAMKILEDGVACDVIKIRNQVRNKERFVKRRQRILGPNGSTLKALELLTSTYILVQGNTVAVMGPFKGLKEVRRIIDDCMANIHPIYHIKELMIKRELAKDPTLAEESWDRFLPNFKKKTYTP-FPPAPEKSKVDLQIESGEYFLEVVERQRLFVAPEE Phybl2 WKIDEFFMEESSFATLFPKYRENYLREVWPHVTKSLCVLDLVEGSMTVKTTRKAYDPYIILKARDMIKLLARSVPFPQAVKVMNDNIACDIIKIGNVTRNKERFVKRRQRLIGPNGSTLKAVELLTGCYMMVQGNTVSVMGPYKGLKDIRRIVLDCMKNIHPIYHIKELMIKRELAKDPKLAEESWDRFLPQFKKKEYTP-FPPPQQPSKIDLQLESGEYFL-------------- Picst3 WALEEFFTEESSFMTLFPKYREQYLRSIWADVTKSLCELDLVEGAMTVKTTTKTFDPAIILKARDLIKLLARSVPFPQAVKILQDDIACDVIKIGNFVANKDRFIKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMRNVHPIYYIKELMIKQELSKKPELAEEDWSRFLPSFKKKVYTP-FPPAQTPRKVDLQVESGEYFLEKREKQEEYVAPEE Plicr1 WKVDAFFTEESSFATLFPKYREKYLREVWSAVTSALCTLDLIHGSMTVKTTRKTFDPYIILKARDMVKLLARGVSITQAVKVLDDAVACDIIKIGSLVRNKERFVKRRQRIIGPEGSTLKAIELLTQCYVLVQGNTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPQLATESWDRFLPQFRKKVYTP-FPPAQLPRKVDLQLESGEYFLRRQQKQVEFVAPVE Polpo WKPLPLLYDESSFSTLFPKYREKYIKEIWPLVEKELCKLDLIDGSMSVTTTKKCWDPVAILKARDLIRLLSRSVPFHHAKRIMLDENNCDIIKIGGSVRNKERFVKRRQRLIGPDGATLKSIELLTRCYVLVQGTTVASIGPWDGLLQVNKIVEDCMKNIHPIYNIKEMMIRRELMKDESLKTESWDRFIPKFKKKDTGP-FAPAQLPRKEDLEMASGEYFLEREEKQAELVAPAE Pucgr2 WKIEPFFTEESSFATLFPKYREVYLKEIWSHLTKVLCVLNLVEGSMTVKTTRKTVDPYIILKARDLIKLLARSVPITQAVKILDDNVACDVIKIGNVIRNKERFVKRRQRILGPSGSTLKAIELLTDCYLLVQGTTVSAMGPYKGLKVVRRIVIDCMKNIHPIYHIKELMIKRELAKNPKLAEENWDRFLPNFTKKKYTP-FPPPQMPRKIDLELESGEYFKKKAEGREIDQPPAE Punst1 WKIDPFFTEESSFATLFPKYREKYLQEVWSAVTAALCTLDLIHGSMSVKTTRKTYDPYIILKARDMIKLLARGVAVGQAVKILQDDMACDIIKIGNLVRNKERFVKRRQRIIGPDGSTLKAIELLTRCYVLVQGSTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIKRELAKDPKLATEPWDRFLPQFRRKVYTP-FPPAQLPRKVDLQLESGEYFLRRKEKQAEFVAPAE Rhior3 WKVEEFFTEESSFATLFPKYREAYLKECWPLVTKALCVLDLVEGSMTVKTTRKSWDPYSILKARDLIKLLARSVPFPQAIKIMDDGVACDIIKIGNITRNKERFVKRRQRLIGPNGSTLKAIELLTKCYMMIQGNTVSAMGPYKGLKDLRRIVLDCMKNIHPIYHIKELMIKRELAKDPKLATESWDRFLPKFKKKEYTP-FPPAPVKSKVDLQLESGEYFM-------------- Rhoto1 WKVDPWLLEESSFATLFAKYRETYLREIWGHVTAALATLDLVEGSMTVKTTRKTHDPYIILKARDMIKLLARSVPFPQAVRILEDGMDCDIIKIGNIIRNTERFVKRRQRILGPGGSTLKAIELLTQCYVLVQGNTVAAMGGHKGLKEVRKIVIDCMKNIHPIYHIKELMIKRELAKDPKLASENWDRFLPKFRRKPYTP-FPPAQQPSKIDLQLESGEYFLKRKAKQAEFVAPDE Rozal11 WKIDEFLLEESSFATLFPKYRENYLREIWPTVTAALCVLDLIEGSMTVKTTRKTFDPYIIVKARDLIKLLARSVPFQQAVKILEDGMACDIIKIGTLVRNKERFVKRRQRLIGPNGNTLKAIELLTKCYVLVQGNTVSAMGDFKGLKDVRRIVLDCMKNIHPVYHIKELMIKKELSKDEKLKHENWDRFLPQFKKKEYTP-FPPPQQPRKVDEMIESGEYFLKKKEEQIKFIPPVE Sacce1 WKIEEFFAEESSFMTLFPKYRESYLKTIWNDVTRALCVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKKVYTP-FPPAQLPRKVDLEIESGEYFLEQKEKQMEFIAPEE Salro WANIPYLVEESSFSTLFPKYREQYLREWWPHIERELAELDLVEGSMTVRTTRKTWDPYIIIKARDVIKLLARSVPFQHAKRVLQDEIACEVIKIANIVRNKERFVKRRQRLIGPNGATLKAIELLTDCYMLVQGNTVSCIGPYKGLKQVRKVVLDCMNNIHPVYNIKTLMIKRELMKREDLKGESWDRFLPKFKKKEPSH-LPPEQLPRKVDKEIESGEYFL-------------- Schco3 WKIDPFFFEESSFATLFPKYREKYLKEVWGAVTRALCTLDLVHGSMAVRTTRKTYDPYIILKARDMIKLLARGVAVAQAVKILDDNMACDIIKIGSLVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGSTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIRRELAKDPKLANESWDRFLPAFRKKVYTP-FPPPQQPRKVDLQLESGEYFLKRKEKQADYVAPAE Schpo1 WKIEPFFLEESSFATLFPKYREKYLREVWPHVTRALCVLDLVEGSMTVKTTRKTFDPYSILDARDLIKLLARSVPFPQAVKIMQDGVACDIIKIGNILRNKERFVKRRQRLIGTNGQTLKALELLTQCYILVQGTTVAVMGGYKGLKEVRRIVEDCMHNIHPIYHIKELMIKRELAKDPTLANESWDRFLPQFKKKEYTP-FPPAQPPSKLDLEIESGEYFLEKKEQQKEFIPPEE Sorma WKVDPFFLEESSFMTLFPKYRERYLRDSWPLITKALAVLDLVEGSMTVKTTRKTFDPAAILNARDLIKLLARSVPAPQAIKILEDGMACDIIKIRSMVRNKERFVKRRQRILGQNGTTLKALELLTQTYILVHGNTVSVMGPFKGLKEVRRVVEDTMNNVHPIYMIKELMIKRELAKDPALAHEDWSRYLPNFKKKNYTP-FPPAPEKSKVDLQIESGEYFLERAEKAKAYVPPEE Sphar WKVDPWLLEESMFATLFPKYREKYLKEIWPHVTTLLCVLDLVEGSMTVKTTRKSYDPYAIIKARDLIKLLARSVPLQHASRILEDDSTCDVIKIGNIVRNKERFIKRRQRLVGPDGSTLKAIELLTECYVLVQGNTVSAIGSHKGLKQVRQIVEDCMRNIHPIYNIKTLMIKRELQKDPKLAEENWERFLPQFKKKEYTP-YPPQQQPSKIDMQLESGEYFMKRKAKQSEFVAPEE Spipu1 WKIEEFFLEESSFATLFPKYREAYLREVWPMVTSALCVLDLIEGSMTVKTTRKTWDPYIILKARDLIKLLARSVPYQQAIKVLQDGIACDIIKIGNILRNKERFVKRRQRLIGPNGNTLKAIELLTNCYVMVQGNTVSCMGPHKGLKEVRRIVIDCMKNIHPIYHIKELMIKRELAKDPKLAHESWDRFLPKFRKKSDRPLFPPTQAPRKEDLEIESGEYFLKKKEAQAEFVAPVE Sporo1 WAIEPFFLEESSFATLFPKYREVYLREVWGHVVSSLATLDLVEGSMTVKTTRKTYDPYVILKARDLIKLLARSVPLPQAVKILDDGCHADIIKIGNIIRNNDRFVKRRQRLLGPGGSTLKAIELLTQCYVLVQGNTVAAMGGHKGLKEVRKIVIDCMKNIHPIYHIKELMIKRELAKDPKLAEENWERFLPKFRRKVYTP-FPPAQLPSKIDLQLESGEYFLRRKAKQAAFVAPEE Stehi1 WKVDAFFAEESSFATLFPKYREKYLREAWSAVTRALCTLDLIHGSMSVRTTRKAFDPYMILKARDLIKLLARGVAVTQAVKILDDNVACDIIKIGNLVRNKERFVKRRQRIIGPDGSTLKAIELLTQCYVLVQGSTVSVMGPYKSLKEVRRIVLDCMKNIHPIYRIKELMIKRELAKDPKLATESWDRFLPQFRRKVYTP-FPPAQQPRKVDLQLESGEYFLERKQKQEEFIAPVE Tapde11 WRIDEFFTEESSFATLFPKYRESYLREIWSVVARTMAVLDLVEGSMTVKTTRKTYDPAAILNARDLIKLLARSVPFPQAIKIMEDATASDIIKIGTFTRNKERFVKRRQRLIGPNGSTLKALELLTGCYVLVQGTTVSAMGTYKGLKDVRRVVEDCMQNIHPIYHIKELMIKRELAKDPKLATESWDRFLPQFKKKEYTP-FPPAQLPSKIDLQIESGEYFLQRKEKQDEFVAPDE Thetr WKIDPWLLEESSFATLYPTYREAYLREVWALVTQTLCVLDVIEGSMTVFTTMKTSDPYIIIKARDFIKLLARSVPFEVAKRVLGDDTACDIVKIGNRVRNKERFLKRRKRLIGPQGQTLKALEILTECYILVQGNTVALVGPFKGLKIARRIVEDTFNNVHPIYNIKKLMIKRELAADPALAEESWDRFLPQFKKNAYTP-FPPAQLPRKVDIQLETGEYHLAKAKAAAQFKAPDE Treme1 WKIDPFFAEESSFSLLFPKYREPKLRTWWGEITSKLCELDLVQGKMTVKTTRKTWDPYVVLKGRDMLKLLARGVDPPQVYKILQDDIACDVIPIGGLVRNKERFVKRRARILGPNGSTLKAIELLTECYVLVQGNTVSAMGSYKGLKEVRRIIVDCMNNIHPIYRIKELMIRRELAKDPKLVNENWDRFLPKFQKKIYTP-FPPPQQPSKLDLQMASGEYFLRRLEKQAEFIAPPE Trire2 WKIETFFAEESSFVTLFPKYREVYLKEVWPLITKALCTLDLVEGSMTVKTTRKTFDPAAILNARDLIKLLARSVPAPQAVKILDDGVACDIIKIRNLVRNKERFVKRRQRILGPNGSTLKALELLTETYILVHGNTVSAMGPYKGLKELRRVVEDCMNNIHPIYHIKELMIKRELAKDPELANESWDRFLPNFKKKVYTP-FPPAPEKSKVDKQIESGEYFLDRKEKQKQFVPPEE Umbra1 WKIEEFFTEESSFATLFPKYRENYLKEVWPHVTRALCVLDLVEGSMTVKTTKKTYDPYIILKARDLIKLLARSVPFPQAVKVLDDGISSDIIKIGNVTRNKERFVKRRQRLLGPNGSTLKAIELLTKCYMMVQGNTVSAMGPYQGLKEIRRIVIDCMKNVHPIYHIKELMIKRELAKDPKLATESWDRFLPHFKKKEYTP-FPPAQTLSKIDKQLESGEYFLERKQKQQEFIAPKE Ustma22 WEVPKFFLEESSFATLFPKYRERYLKEVWGHVTSALCTLDLVEGSMTVKTTRKTYDPYIVLKARDMIRLLSRSVPFPQAVKILEDGIECDVIKIGNLLRNKERFVKRRQRIIGPNGSTLKAIELLTNCYVLVQGNTVCAMGQFKNLKEVRRIVIDCLKNIHPIYHIKELMIKRELAKDPKLAQENWERFLPKFKKKTYTP-FPPPQQPSKIDLQLESGEYFLQKLAKQADFVPPTE Walse1 WKVDTFFAEESSFATLFPKYREKYLREVWPHVTRALCVLDMVEGSMTVKTTRKTYDPYIILKARDLIKLLSRSVPFSQAVKVLEDEYAADIIKIGGLVRNKDRFVKRRQRIIGPNGNTLKAIELLTECYILVQGNTVSVMGPFKGLKNVRRIILDCMNNVHPIYHIKELMIKRQLAEDPNLAGESWDRFLPSFKKKVYTP-FPPPQQPKKIDLQIESGEYFLERKHTQEELVAPDE Zygro1 WHQDEFFAEESSFMTLFPKYREAYLKSIWNDVTKALCVLDLVEGSMTVKTTRKTCDPAIILKARDLIKLLARSVPFPQAVKILEDNTACDVIKIGNTVANKERFQKRRQRLVGPNGNTLKALELLTKCYILVQGNTVAAMGNYKGLKEVRRVVEDTMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPNFKKKVYTP-FPPAQTPRKVDLEIESGEYFLERREKQAEFLPPKE [Cluster2113.fasta_al_trimmed; alignment length = 148] Allma1 IELATSLLVQAPPGELADVLNDVRVLPALAKYNKDQVILCDAARFMDPISKKTFAIDHVVSTEDALQTSLNAYLKSHYPNGLVLVDSKYNPDNFWTGRWRSAWILVHYYEDGNVQLATVVKAIMNESAFRVLRRALPLTKAKVDWNKI Ashgo11 SDIITQLLFDAPPREINSVYDSLVIIDALKRCLVAKTIVTEYNKYFDPFKKVLFSVDCLGLDIELYEE-LQKYVAKNFPGDIIIVSSKFSPSNYWSGYWKSEYVVVHYFEDGNVKFSTPISCILNQTQFAKLRRKLPVTRSKVNWGKA Aspfu1 VELASSFIEGAPPGE---------ALPAFERYNEKQVIVSEFNRYFDVESQTSFGVDHVASGAQSLLKSLAKHAAEHYPNCILLVANRYSPNNFWNGRFRSIYVDVHYYEDGNVALNTIISRIMAEGAFKNLRRQLPITRQKVEWEKV Aurde31 IEAASSFLLQSPPGEINDVLNDIRTIPALHKYNVAQVIISEAGRFIDPRSKQSFAFDHLASDTQALERATLAYVEDHFHDGVQIVANKYNPPNFWAGRWRSEYVNVHYYEQGNVQLATILALIMADKSFKSLRRALPLTKQKLDWDKV Batde5 LEIVSGFIKDSPPGEINDVFNDVRSLSTFADHHAKQVILGEYGKYVDPRSGQALIVDLVVKSVEALDVAVQEYTASFYPSSIAIVANKYHPDSFWSGRWRSLWVQVHYYEDGNVQHNSVIKHILALETFKSLRRALPISRTKIEWQGI Botbo1 IAAASKFLLQSPPGEINDVLNDIRAIPALREYNLAQVIISRASRYVDPKAGITFSLDHLTSDPQSLETAASKYVSDHFPDGIQIVANKYNPTNFWSGRWRSEYINAHYYEQGNVQLASIVALIMGDKTFKGLRRMLPMTRQKIDWDRV Botci1 IETVSAFVEGAPPGELADVIADIKALPAFEKYNEEQVIISSYNRYYDIETSSSFLFDHTASAVQSILKSLGPHVAEHFPNAILVVANKYSPNNFWNGRWRSLYVDVHYYEDGNVRLLTIVREILSEGAFKGLRRQLPITRQKIEWDKI Caeel VRIASDFIKHAPPGEFNEVFNSVRMLNAIAQYNVGQTLITPYNRFYDEVSKKSFKYDHVAADLQALQTQLDIYIDDHYAKSICIESHQFQPKNFCNGRWRSEWSQVHYYEDGNVQLFSIIHAIMSDTTFKALRRQLPVTRAKMDWNKA Canalb1 NELVDSLIQSAPPAELKQVSQSLSSLDSIEQYAQENIIISKYNKYIDYVNNKLFNVDWQIIDVELIQK-LSQYGDDYYPSNVIIIGQRANHDNFYTGQWKSNYLDIHYFEDGNVRLKFIVNFILNQKSFKNLRRLLPVTRSKINWGSA Cangl DTIIKNIIKDSPAGELEEVYQDLITIDAIAEYNVENVIISKYNKFVDPVNGIQFSVDHLGLDVEAITD-LGNYLSTNFPGRIIIVSTKYNPSNFWNGHWKSEYIDVHYYEDGNVKFHSPVASILNEKQFKSLRRRLPITRARVNWGKA Capow VKIASSFILAAPAGEFNEVFNDVRVLNAFSQYNKDQTLITKHNTFFDPRSGQTFSFDHLADNAQAIDNAIRKYTENHYPDGICIEDHKFNPNNFWNGRWRSEWVQVHYYEDGNVQLQTIIAVIMSDTTFKALRRVLPVTRSKIEWGKM Catan2 IDIANDFIAQAPPGELENVLADLRVLSGIEKYNLDQPILCEPARFIDPRANKSFAVDHAISDSADLQTHLDSYIQSHYPRGIVIVDSKYKSDNFWNGRWRSHWATVHYFENGNVQLAFVIKAIMSDNAFRNLRRALPLTKAKVDWNKL Cioin QRIAHDFITHAPPGEVETVFSDVRHLASLSKYRVDQVLLTNHGRFLDPRSKKSFHCNIPISDIQEIDNALAKYIKEHFPHGACIEDHKFSPENFWNGRWRSEWTQVHYYEDGNVQLVSVTKLILSTTTFKALRRQLPVTRTKIDWNKI CocheC53 TAALSSFIDSAPPGELADVTKAIKSIPAFQKYNEEQVLVSQYNRYYDIDTQSSFDFDHVASAVQSLNKALSTHAAEHYPKSIITVANKYSPTNYWNGRWRSSYVDVHYYEDGNVRLLTVVRKILSEGAFKSLRRQLPITRQKIEWEKI Coere1 IAKAASLLLQSPPGEVDDVFNDIRGIPVLAESNMQQVLITPYNQYLDPRTRTVFTFDHLGSEAQALQKELDKYILAHYGAGTCIVSNRFSPTNFWNGSWRAVWVRVHYFEDGNVQLDTVVKFILAEKTFKGLRRTLPVTRTKMDWEKI Conco1 VELASEFLLDAPPGELNDVIGDIRGLPSLQKYNLDNVLLSNYNYFVDPRSQQKFKFDHLISDIESLDTEVQKYTSQYYEDGVLIIGTKLNSKNYWNGQWKSIWTKVHYYEEGNVQLDSVIKQILAERAFSGLRRALPLTKTKMDWSKV Conpu1 IQAASSFLLQAPPGEINDVLNDVRAVPALREYNLTQTIVSEIARYLDPRSKTSFRFDHLATDPQALEKATQLYLSAHYHDGIQVVANKYNPNNYWSGRWRSQYVHVHYYEQGNVQLTTILAQIMGEKTFKGLRRALPMTRQKLDWDKV Copci IQAVSNFLLQSPPGEINDVLNDVRNIPALKEYNVTQSIISEAARFWDPRSKTSFVFDHLASDPQALQKAALTYISSHFLDGVQVVANKYNPTNYWSGRWRSQYVNVHYYEQGNVQLAAIIALIMSERTFKGLRRALPLTRQKIDWDKV Croqu1 LAVASAFILQSPPGEVNDVFNDVRPIPALSQYNTEQAMICAAARFLDPNSSQTFVFDHLATEVEQLSEEAEKYVKEHFPGGLYIVGNKYNPGNYWTGRWRSVYVNVHYYEQGNVQLTTIIKAILGDNTFKQLRRALPLTKQKIDWNNI CryneH991 CKLAARLVEQTPPGEINDVINDIRAIPALRSYNLSQSLLSEAVRYVDNIGKKSFAFDHLVSDYQELAKSLEAYSKNHFPSGLEVVGNRYNPSNFWTGRWRTHWVDVHYYEQGNVQLATIVTTILGEKSFRALRRALPVTRQKVDWDKV Crypa2 VEWVSSFVGDAPPGELSDVVADIKALPAFQKYNEEQVIVSSHNRYYDIENSSSFEFDHAASGVQSTQKSLGTYVKEHFPNAIIVVGNKYSPNNFWNGRWRSLYVDVHYYEDGNVRLVTIAKEILSEGAFKGLRRQLPVTRQKIEWDKV Debha1 DTIVSSLVKSSPPGELDGISQDLSAITAIEKYINENYIASKINKYIDFIGKKLFNIDLHAIDFELVKK-LTEYGEDHYPSKIIIIGQKLNYENFYTGLWKSHYLDIHYYEDGNVRLNFIVNFILNQKYFKNLRRLLPVTRSKINWGQA Dekbr2 QGIIRSMIEDAPPGSAAPLQKDIKTIEDLKQYHLNKGIISKYNKYYDPLLKLKFDYDFDVIDIELNEK-ICDYALQHFPTFIIIVDENLNDANFYNGRWQSFYVKVHYYEDGNVALNTIVETILNEHQFKNLRRQLPINRSKVQWGKS Dicdi VQIATNFLLNAPPCEFMEVVSDVRALSTFREYNTSQALITKEGEYLDPKNKQVITYDHIVTGERAFDEEATKYCNEYYPNGVCISTCIYKPNAFYSGRWRSVWVNVHYFEDGNVQLNTAFKAIMGDTTFKALRRALPINRTKINWQKV Dmel VRIVSDFILHAPPGEFNEVFNDVRELHAFAQYNKDQAIISEHNRFYDPRTKQAFKYDHLASDYQALDLETLAYTASHYRHGICIEDHQFQPKNYWNGRWRSQWVQVHYYEDGNVQLVSVIRLIMSDTTFKAMRRQLPITRTKIDWSKI Enthi TKIVTTFLKDSPPGEFNNVLKDCREVICLHDYNTEQVIISKYTEFIDPVNKKVVTFDHLITSSQALQKKLDNYAKEFYPKGIIISAADLKVAQFSNGKWRSEWVQVHYFEDANIQMHTVIKEILSDNCLKALRRQLPISRQKINWANW Falba MEIASDFIQQAPPGGLHEVYNDLRHLQAMSTYNISQSLVTRFNVFYDSTTGATFAFDHFVSAGSELERAAKDYLNEYYPDGICFASDRYSPRNFWNGRWRSEWAHVHYYEDGNVQLQTVVKAILGDTTFKALRRALPITRNRVDWEKI Fomme1 IQAASRFLLQSPPGEINDVLNDVRDIPSLEEYNLEQVIVSEAGRFLDPRSKTTFIFDHLASDPQALETATTTYLANHFVDGIQVVANKYNPSNFWSGRWRSEYVNVHYYEQGNVQLSTIIALIMSEKTFKGLRRALPLTRQKLDWDKV Fusgr1 IETVSSFVEGAPPGELADVIADIKSLPAFEKYNEEQVIISSYNRYFDVESSSSFTFDHTASAVQSTLKSIGPYVDEHFANAIVIVGNKYSPNNFWNGRWRSLYVDVHYYEDGNVRLLTIVREILSEGAFKGLRRQLPVTRQKIEWDRV Galma1 SQKLST---------------------------------SEAARFLDPRSKISFVFDHLASDPQALEAAALNYLKAHFTDGIQVVANKYNPTNFWSGRWRSEYINIHYYEQGNVQLTTILALIMGEKTFKGLRRALPLTRQKLDWDKV Ganpr1 LKIASNFLLQAPPGELNDVFNDVRALGAFSTYDTEQVLLTQYNRYFDPRTSSTFEYDHIAGPLEALDTALQKYVREHFPEGACVNSGRYSASNYWTGLWRSVWAYVHYYEDGNVQLESALKLITSESAFRQLRRALPITRNKIDWAKI Gloin1 LKIVTNFLLSSPPGEADEVFNDVRVLDALREYNTEQVLVSKFGLYLDPKSHQAFRFDHMATEVEAVEAAITNYVEDHFKDGIAIVDNKYNSSNFWNGRWRSTWVNVHYYEDGNVQLDSYVRLILSENTFKSLRRSLPLTRQKLDWDKI Hisca1 LEIASSFIRGAPPGELSDVVADIKALPAFEKYNEEQ------------ETQTSFQFDHVASSPQSLLKSLSAHAREHYPSCILLVANKYSPNNFWNGRYRAIYINVHYYEDGNVSLNTVIKRILSEGAFKGLRRQLPITRQKVEWEKV Klula1 EKIVRDIVFDSPPEEISLVYDNLQVLSIIQEFNEKHYLVSEYNKYFDPVNKVLFAVDHIASDIELYDE-LSKYVSNFFPDTIIVVSNKKSLGDFWTGYWLSEYVDAHYFEDGNVRFKSPIVSIMNETQFKGLRRRLPVTRAKINWGQG Lacbi2 VQIASTFLLQSPPGEINDVLNDVRNIPALREYNIAQSIISEAARFLDPRSKTSFVFDHLASNPQALQTAALLYLSSHFQDGIQVVANKYNPTNFWSGRWRSEYANVHYYEQGNVQLSTIIALIMGEKTFKGLRRALPLTRQKIDWDKV Lenti61 IEAASKFLLQSPPGEINDVLNDVRNIPALREYNTTQSIVSEAARYWDPRSRTSFRFDHLTSDPEALETASLAYLQAHYHDGIQIVANKYNPNNYWSGRWRSEYVNVHYYEQGNVQLSTALALIMSEKTFKGLRRALPMTRSKLDWDRV Malgl1 IQACLELILQSPPGQQSHIVSDLKGMSILLQYTHEQSAIVCDAKYYHPRLSCSFSYDPIVSEVSEVDQQLSKYVLNHYHTGI--VGNKYNLRNFWTGRWRSTYVQTHYFENGNVQLQAVIQAILREHAFKALRRTLPITRQKIDWSKI Mellp23 ISVASNFILQSPPGEVNDVFNDVRPIPALSQYNTEQAMICEAALYMDPNSSQTFIFDHLVKDVKEISNQAEKYVKEHYQGGLYIVGNKYNPGNYWTGRWRSIYVNVHYYEQGNVSLSSVIKSILGDDTFKQLRRALPVTKQKIDWNNI Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------- Monbr VAIASDFVMNAPPGEFNEVFNDVRVLEAFVNYNEESVLITKHGRYIDPKTKQVFKFDHLVSDLEAVETEAETYVKDHYHTGVCVEDHKYQPRNFWNGRWRSEWVHVHYYEDGNVQLRSLFKIVMSETTFKALRRALPITRSKVDWNKI Morel2 IKIASKFLKAAPPGEINDVFNDVRALAALEEYNTEEVIVSKHGRFLDPKTNQTFKLDHLASDLEAIEIDTEAYVADRYAEGIAIVHNKYSPSNYWNGRWRSIWCKVHYYEDGNVQLETLLDFILAESTFNGLRRALPYTRTKLDWNKI Mucci2 VKIASDFLLSSPPGEVNDVFNDVRTLQALEQYNTEQVIVSKYGRYLDPRSKQTFKFDHMASDVEAVEKECLAYVNDHFPNGIAIVDNKYNPNNFWNGRWLASWVNVHYYEDGNVQLNAIVKEILAENTFKGLRRALPMTRNKMDWNKI Mydma VRIASSFIKNAPPGEFNEVFNDVRILYAFAEYNTDQVLITKHGIFYDPKSKQKFQYDHLANGLEAVDDSLRKYVKGHYPNGICIEDHLFQPQNFWNGRWRSEWVQVHYYEDGNVQLVSISKIAMSETTFKALRRQLPITRTKIDWSKI Neucr2 KEIVSSFVEGAPPGELADVVADIKALPAFQKYNEEQVIISSHSRYYDVESSSSFAYDHIASDVQSTVKGLSAYVKEHFPNAVVIVANKYSPNNFWNGRWRSLYVDVHYYEDGNVRLLTIAKEILSEGAFKGLRRQLPVTRQKIEWDKV Orpsp11 LKIAHQFILESPPGELNDVFNDVIVLS-FQEYNNANAIISKFGHYLDPRSGNSFAFDHFVDDVQAVDKEVQKYVSEHFPDGIIITANKYNPDNYWNGRWRSIYSNVHYYEDGNVQLEWIAKGIQANNVLKALRRALPVTKQKMDWNQI Pench1 VELASSFIEGAPPGELADVVADVQALPAFKRYNEAQVIVSGFNRYFDPESQTSFEVDHTASAAQSLLKLFGVHAREHYPNCIVLVANRYSPNNFWNGRFRAIYVDVHYYEDGNVALNTIVSRITSEGVFKGLRRQLPITRQKVEWEKV Phybl2 VKIASGFLLASPPGEVNDVFNDVRTLTTLEEYNTEQVIVSKHGRYLDPRSKKSFQFDHIATELKAVETEAHKYVNDHYPNGIAIVDNKYNPNNYWNGRWLATWVHVHYYEDGNVQLNSIVKEILAENAFKGLRRALPLTRNKLDWNKI Picst3 DSLVNSLVESAAPTELPYVSKDLS-IDSIEEFVNEKYIASKHNKYIDFISKKKFNIDINAIDFELVEK-LGQYGEDHYPSTIIIIGQRLNHENFFTGQWKSIYLDIHYYEDGNVRLNFIINAILNQKYFKNLRRLLPVTRSKINWGSA Plicr1 IQAASSFILQSPPGEINDVLNDVRTIPALKEYNVAQTIVSEAARFLDPRSKQSYHFDHLASDPEALESSALAYLAEHYHDGIQVVANKYNPSNYWAGRWRSEYVNVHYYEQGNVQLSTILALIMGEKTFKGLRRALPLTRQKIDWDKV Polpo VSIATNFLLSAPPGEFNEIVSDVRTLDTFREYNTEQVLLTKRGEYLDPKGKVVITYDHIVTGSRAFEEEAFKYCNEFYPTGVCLSSSKLNPNNFWNGRWRSTWINVHYYEDGNVQLNTVFKAIMGDTTFKALRRALPITKLKINWNKI Pucgr2 ---------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 IEIASKFLLQSPPGEINDVLNHIRNIPALQEYNLAQSIISDAARFLDPRSKQTFVFDHLTSDPQALEKATLDYLSNHFHDGIQIVANKYNPNNFWSGRWRSEYVNVHYYEQGNVQLETVVALIMGSKTFKDLRRALPLTRQKLDWDRV Rhior3 VKIASSFLLSSPPGEVNDVFNDVRTLQTLEQYNTEQVIICKHGRYLDPRSKKTFKFDHVASDLEAVQTEALKYVDDHYPNGIAIVDNKYNPNNFWNGRWLASWVNVHYYEDGNVQLNA-----VC----------------------- Rhoto1 LDAASTFLLQSPPGEVNDVLSDLRAIPALTKHNAEQVLVTPASRHVQLREGKEFVFDHLASSASSLDKLLSSYVANHYASGLYFVGNKYNPSNYWTGRWRSTYINIHYYEQGNVQLSTVVASILSDASFRGLRRALPKTRSKLDWDKA Rozal11 RQIVMKFIESAPPGALGDIVNDLRVI-SCKKYNENNNIVCSYNLYYNPKSGTIFSIDHLGKSVGEVTTEYESYLNDYYSNPLICTAVK-------NAKWSSIWADAHYFEDGNVQMKCVVKKIICETTFKSLRRALPVTRNKIDWEKI Sacce1 EEVINKIINDSPPGELREVYDDLIKIDAIENYNVQNVIISKYNKFFDPVNSVIFSVNHLGLDIEELHDKLHEYLLQSFPGDIIIVSTKYNPNNFWNGHWRSSYTQVHYYEDGNVSFQSVVCTILNEKQFKALRRRLPVTRSKINWGSA Salro VQIAKDFLANAPPGEFNEVFNDVRVLEAFSTYNEDQVLVTTAGRYKHPSKSKVFSFDHLVDEIAEVEAAAHDYAKEEH------------------------------------------------------RRA------------- Schco3 VEAASNFLLQSPPGEINDVLNDVRNISTLREYNLEQTLISRAARFLDPRSKTSFLFDHIASDPQALETATQTYLAAHFVEGIQVVSNKYNPNNFWSGRWRSEYLNVHYYEQGNVQLNTILALIMGEKTFKALRRALPMTRQKLDWDKV Schpo1 KEAIYKLIRESPPGEVNQVVHDIRDILYHEDYNSS-VIISADNRYYDQVLQKSFTINYEAENVEEIVKQIKKVASDHYLSDIVLVSSKYNPKNYWNGSWRCICIRVHYYEDGNVWLDALYEVLLNDKKFKELRRQLPVTRQKINWENV Sorma KEIVSSFVEGAPPGEVHEAEEYIKALPAFQKYNEEQVIISSHSRYYDVESSSSFAYDHIASDVQSTIKGLSAYVKEHFPNAVIIVANKYSPNNFWNGRWRSLYVDVHYYEDGNVRLLTIAKEILSEGAFKGLRRQLPVTRQKIEWDKV Sphar VKICADFIQTGPPGQFTDVYNDVRALPAAAKLHRDSAMVTPHGCYLEPRTQRTFSFNPIVESIEAIQTAVDEYVEQYYVDGVCIESHKFSLANFWCGMWTSEYMRVHYFEDANIQLQAVGKYLMAGDCFKSLRRALPITKSKLDWGKI Spipu1 LSIVSGFLLDSPPGELNDVFNDVRVLSIFEEYNLEQVILSKYGRYLDPRSSQTFYVDHITSDAEALDQAAAKYIAEHYPNGLQIVGNKYNPDNFWNGRWRSIWVNVHYYEDGNVQLTAAIKQILSEGIFKGLRRALPITRNKINWDSI Sporo1 LAAAQSFLVQSPPGEINDVFTDLRVLPALKEYNLSQVIVTP--RHLNWRTSESFSFDHMASSPSSIDKLFEKHVENHYHDGLYLVGNKYNPNNYWTGRWRSNYINIHYYEQGNVQFSTVVSSIMSEETFKGLRRALPKTRSKVDWNKA Stehi1 IEAVSRFLLQSPPGEINDVLNDVRNIPALQEYNLAQSIVSTAARFLDPRSKTTFVFDHVSSEPEALESSTLTYLFGHFHDGIQVVANKYNPNNYWSGRWRSEYLNVHYYEQGNVQLETILALIMGEKTFKGLRRALPLTRQKIDWDKV Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------- Thetr LEIVTGFLLDAPPGEFNEVVTDVRTLATAQAYNTSHVLLTKYGEYLDPRSAQVVTVDHAVTGTAAVDAAMVAYVAEFYPNGICISAAKFSPGNFWNGRWRSVWLLVHYYEDGNVQLNSAAAEIMSERTFKGLRRKLPVTRHLMDWEKT Treme1 MNQVVELIHLAPPGQLKEVFDDLSIIDELQRFNRQQSIISEGSRYVDYETERSFILDDTPVEYAELEKSLKAYVKDSYPTGLEIVAELNNKANFWTGKWQSEWVDVHYFEQTNVRLQSIVTRVLDQDSLKRLRRVLPASGSKIDWDQV Trire2 IETISSFVKGAPPGELADVVADIKALPAFEKYNEEQVLISPHNRYYDVESSSSFEVDHLASAVQSTLKSLGTYVKEHFPNAIVIVANKYSPNNFWNGRWRSVYVDVHYYEDGNVRLLTIVKEILSEGAFKGLRRQLPVTRQKIEWERV Umbra1 VQIAASFLLESPPGEVNDVFNDIRTLTSLEDHNTEQVIISKFGRFADPRSKQSFAFDHMASDLQAIDNQVQAYVSDHYPHGIVIVDNKYNPSNYWNGRWRAVWVQVHYYEDGNVQLNSIVKAILSENTFKELRRALPYTRNKVDWHKI Ustma22 LNEALSLLVQSPPGQTSQVYHDLRGIVALEEYNTQQVIICQAGRYLHAKLKKTFLFDHVVSDVKALEHALESYVKDRYPDGIHHVGNRFNLSNFWSGRWRASYVQVHYFENGNVQLNAVVSVILAESAFKALRRQLPLTRQKVDWDKV Walse1 TEIVKKILKQSPPNELNDVLEDLK-VTCLKEYNEEQTLITPHSKYYDPKSSKLFTLNQLTNSAELLEKSLDSYVEEYFSNGICYAGNKFNQSNYWSGRWRANWITIHYFENGNVQLQALVKAILSEKLFRSLRRALPITREKINWDKV Zygro1 ESIISQIVSDTPSGEVKEVYQDLITIEAIEQYNVKNVILSPYNKFFDPAQAIEFSVDHLGLDVAYLKE-LNKYVEKDFTGQIIIVSTKYNPGNFWNGAWKSEYVQVHYYEDGNVGFKSPIKSILNEKQFKQLRRRLPITRSRVNWGKA [Cluster2115.fasta_al_trimmed; alignment length = 79] Allma1 DLFE--VQRGLNNAFSYDLVPSTDICEAALRACRRVNDYPTAVRVFEGIKQKVPADKHEYLTALKPIREELGIETREEL Ashgo11 DLFE--VQRVLNNCFSYDLVPAPVIIEKALRAARRVNDLPTAIRVFEALKYKVENEEQAYLEELSEVRKELGVPLKEEL Aspfu1 DVFE--LQRNLNNCFAYDLVPSVEVLSAALRAARRVNDFPTAVRIFEGIKAKVETQDQQYLESLEGLRQELGVALREEL Aurde31 DLFE--LQRGLNNCFAHDLVPAPGIIEAALRASRRVDDYATAVRIFEGVREKTENKQQAYLAELKGVKEELGVETKEEM Batde5 DDFE--LERGLNHIFAADWVPSVELVALTLKAARRLDSFPTAVRILEGLKDKAYKPEQAYIRELKPLLEELGIPEKQDL Botbo1 DLFE--LQRGLNNCFAYDLVPSPAVVEEAVRAARRVNDYSTAVRIFEGLREKVENKKQQYLEELKGVRQELGILTKEEM Botci1 ------------------------------------------------------------------------------- Caeel DGWE--VRKALSELHDYDVIPDPKVVEAALRACRRVNDFALAVRFLEAIKIKCGAQKNYIVKQVEPVLKELGIDTPEQL Canalb1 DLFE--VQRILNNCFAYDLVPAPAVIEKALQACRRVNDYPTAVRTFEALKFKVETPEQAYLEELKDIRKELGIDLKEDL Cangl DLFE--VQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAVRVFEALKYKVENEDQAYLDELKEVREELGVPLKEDL Capow DLWE--LRNGLNTLLAHDVIPEPAIVAAALRQARRHNDFALAVRTLEAIRVKSNLDKSWMMKELKPVIDELHISLPEEL Catan2 DLFE--VQRGLNNCFSYDLVPSTQIVEAALVACRRVNDYPTAVRVFEGLKQKCPSEKQEYLEATKELREQLGVETREEL Cioin DYVI--FKIGFMNLYQEDSVPEPAIVQAALYACRRINNLPLAMRVLEMVKNKCDDRQDYIVQELRPSLDDLGLKTVEEY CocheC53 DVFE--LQRNLNNCFAYDLVPSPAVITAALRAARRVNDFPSAVRVFEGIKFKVENKGQEYLQELEPIREELGIPLKETL Coere1 EQFE--LQRGLNNCFAYDLVPDVSICEAALRAARRIDDYATAVRVFEALKIKVDKPTQDYLQALKPVMDELGVQTKEEL Conco1 DVFE--LQRGLNNCFAYDLVPSPAVIESAIKASRRVNDFATAVRIFEGIKDKVENEGQSYLNELKHIKEEYGINTKEEL Conpu1 DLFE--VQRGLNNCFAHDLVPSPGVIEAALHAARRVNDYATAVRVLEGVREKVENKQQAYLEELKSVREELGIQTKEEL Copci DLFE--VQRGLNNCFSHDLVPSPEVITAAVQAARRVNCYATAVRIFEGVKEKVENEAQAYVEELKPLREELGISLKEEL Croqu1 DLFE--LQRGLNNCFAYDLVPAVPTIEAALKAARRVNDLPTAIRIFEGLKQKVENKTQAYLDELKTLREDLGVPTKEEL CryneH991 DLFE--LQRGLNNAFAYDLVPSTEVINAALQAARKVNDYATAVRILEGVKEKVENKGQAYLDELKPTIEELGINTKEEL Crypa2 DVFE--LQRNLNNAFAYDLVPSPSVCIAALRAARRVNDYPTAVRIFEGIKSKVENNEQQYLKELQPLRQELGVLLKEDL Debha1 DLFE--VQRILNNCFSYDLVPAPAVIEKALQACRRVNDYPTAVRTFEALKHKVENNEQAYLEELKDIRQELGIDLKEDL Dekbr2 DLFE--VQRVLNNCFSYDLVPSPAVIEKALRACRRVNDYATAVRVFEGLKHKVENPQQAYSDELKDVREELGIDLKEEM Dicdi ------------------------------------------------------------------------------- Dmel DGWE--IRKGMNDLLGMDLVPSPKIIEAGLRASRRVNDIALAIRWLEGCKDKCGDQKAYLLEKITPTLQELGIPTIEEL Enthi ------------------------------------------------------------------------------- Falba DIEE--VHRGLTNLFSHDVIPGSKILESALYACRRLNDFPTSVRILGALEGKLRKEKPAYLVELGPVMAKLGVPSPAEI Fomme1 ------------------------------------------------------------------------------- Fusgr1 ---------------------------------------------MTGIKTKVENKGQQYLEELKPLREELGVPLKEEL Galma1 DLFE--VQRGLNNCFAHDLVPSTAVVEAAVHAARRVNDYATAVRVFEGVKEKVESKSQAYVDELKPLREELGLTLKEEL Ganpr1 DEYD--FEVGLNEVFVHDWVPALSVVEEALKAARRLNSFPTAVRILEGIEERAENKSQQYLTELKPLLTDLGVTTKEEL Gloin1 DRFE--LSRGLNNCFAHDLVPAPSVIEASLRAARRVNDFSTAVRVFEGLKQKVENDGQQYLEELKPIKEELGILTKEEL Hisca1 DVFE--LQRNLNNAFAYDLVPSVSVMTAALKAARRVNDFPTAVRIFEGIRAKVENKAQMYLQELKGLREELGVTLQEEL Klula1 DLFE--VQRVLNNCFSYDLVPAPAVIEKALRAARKVNDLPTAVRVFEALRYKVENEDQAYLDELKDVREELGIPLKEEL Lacbi2 DLFE--VQRGLNNCFAHDLVPSASVVEAAIRAARRVNDYATAVRVFEGIKEKVENKAQAYVDELRPLREELGLELKEEL Lenti61 DLFE--VQRGLNNCFAHDLVPAPAVVEAAVRAARRVNDYATAVRVFEGIKEKVENKQQSYLDELKPLREELGINIREEL Malgl1 DQFE--AQRGLNNAFAHDLVPSPEVIESALKAARRVNDFSLAVRIFEGLKFKTENDNQQYLEVLKPLREELGVPLKEEI Mellp23 DLFE--LQRGLNNCFAYDLVPAVPTIEAALKAARRVNDLPTAIRIFEGLKEKVENKTQAYLDELKVLKEELGVPTKEEL Mnele DTYE--LRRGCNIVHDLDMIPEPSLVEHMFHACRRLNDYPMTIR--------------F-------------------- Monbr DSGA--IRRGLNDLFAHDLVPEPAILEQALRACRRVNDFSTSVRIFEGVMDKAPDATTYVVSQLKPVIAELEVTLPEEL Morel2 DVFE--LQRGLNNAFGYDLVPSPSVIAAALKASRRVDDYATAVRVFEGLKVKAGSDALQYLDELAPLKNELGVQTKEEL Mucci2 DLFE--LQRGLNNAFAYDLVPAPSVIEAALKASRRVDDFATAVRVFEGLKDKVESDKQEYLDELAPIRSELGILTKEEL Mydma DGWE--LRRGMNNLYGYDLVPEPKIIIAALKACRRLDDFAMSVRILEMVREKAAGDKEFINNQLKGTLDELGISTPEEL Neucr2 DVFE--LQRNLNNAFAYDLVPSPSVLAAALKAARRVNDFPTAVRVFEGIKAKVENKGQQYLAELKPLREELGITLKEDL Orpsp11 ------------------------------------------------------------------------------- Pench1 DVFE--LQRNLNNCFAYDLVPSVEVLTAALKAARRVNDFPTAVRVFEGVKAKVENPDQQYLESLEGLRVELGVALREEL Phybl2 DLFE--LQRGLNNAFAYDLVPAPSVVEAALKASRRVNDYATAVRIFEGLKEKVESEKQEYLKELAPLKQELGVLTKEEL Picst3 DLFE--VQRTLNNCFSYDLVPAPVVIEKALQACRRVNDYPTAVRTFEALKHKVENKEQAYLDELKDIRQELGIDLKEDL Plicr1 DLFE--VQRGLNNCFAHDLVPAPEVVEAAVRAARRVNDYATAVRVFQGVQEKVENKQQAYLDELKGVREELGIQTKEEL Polpo ------------------------------------------------------------------------------- Pucgr2 DLFE--LQRGLNNCFAYDLVPAVPTVEAALRAARRVNDLPTAIRIFEGLKEKVENKGQAYLDELKPLRDELGVPTKEEM Punst1 DLFE--VQRGLNNCFSHDLVPAPTVCEAALRAARRVDDYATAVRVFEGIREKVENKKQAYLDELKGVREELGQ------ Rhior3 DLFE--LQRGLNNAFAYDLVPAPSVIESALKASRRVNDFATAVRVFEGLKDKVENEGQQYLEELAPIRQELGVLTKEEL Rhoto1 DLFE--LQRGLNNCFSYDLVPSQRVVEEALRACRRVNDFSTAVRVYEGLKEKTENATQQYVDETKALRDELGILLKEEL Rozal11 DIIE--LQCVLTNVFGYDVVPTAPIIEAAIKKARLFNDFPTCVRIFVALRSITPKLTHEYLEYFKPLMDELGINSPEEL Sacce1 DLFE--VQRVLNNCFSYDLVPAPAVIEKALRAARRVNDLPTAIRVFEALKYKVENEDQAYLDELKDVRQELGVPLKEEL Salro DEHA--IRRGLNDLFAHDLVPEPVILEQALRACRRVNDFSTCVRVFEGVKDKSPDDETYVVGQLKPVIEELQLTLPEEL Schco3 DLFE--VQRGLNNCFAHDLVPAPEVIEAALRASRRVDSLSTAVRVFEGLKEKVENKQQAYVDELKGVREELGIPLKEEL Schpo1 DQFE--LQRGLNNCFAYDIVPSSDVIEQALRAARRVNDFPTAVRIFEGIKVKLPTKEQAYVKELKPVCNELGIVLKEDL Sorma DVFE--LQRNLNNAFAYDLVPSPSVLAAALKAARRVNDFPTAVRVFEGIKAKVENKGQQYLAELKPLREELGITLKEDL Sphar NIRKKVLHRGLNDVFAHDLVPEVEILVAAIEASRRVNSFGTSVRIMEGLREKVATQADYMIEQLRPTLDKNGVSTPEEL Spipu1 DDFE--LERGLNHIFSTDWVPSVEVISDALQATRKLNSFATAVRLLEALEGKAHSKDQNYLKELKPLLEELGVVEKKDL Sporo1 DLFE--LQRGLNNCFAYDLVPSQQVVEEALRAARRVNDYSTAVRIFEGLKEKTENASQQYVQETKPLREELGILLKEEL Stehi1 DLFE--VQRGLNNCFAHDLVPAPAVCESALRAARRVNDFATAVRIFEGIQEKVENKTQAYLDELKPIREELGIATKEEL Tapde11 DLFE--LQRGLNNCFAYDLVPSVGVIEQALRASRRVNDFATSVRIFEGIAQKVENKGQQYLEELKPIREELGITLKENL Thetr ------------------------------------------------------------------------------- Treme1 DLFE--LQRGLNNCFAYDLVPTTEVIEAALKCSRKVNDYATAVRILEGIKEKVENKGQAYLKELKPVIDELGISSKEEL Trire2 DVFE--LQRNLNNAFAYDLVPSPSVVAAALKAARRVNDFATAVRIFEGIKAKVENKNQQYLDELKPLREELGVPLKEDL Umbra1 DLFE--LQRGLNNCFAYDLVPSVAVIEAALKASRRVNDFPTSVRIFEGIEDKVENKKQEYLDELAPLRKELGIETKNEL Ustma22 DLFE--LQRGLNNCFAYDLVPSPEVIESALRASRRVNDYSTAVRIFEGIKQKVENEGQQYVDALKGVREELGIQLKEEL Walse1 DLFE--LQRGLNNCFAYDLVPAPEICESAIRASRRVNDFSTAVRIFEGIKEKVENQGQQYLDALKPLREELGIPTKEEL Zygro1 DLFE--VQRVLNNCFSYDLVPAPAVVEKALRAARRVNDLPTAIRVFEALKYKVENETQAYLDELNDVRQELGIPLKEEL [Cluster2128.fasta_al_trimmed; alignment length = 131] Allma1 MRA-VLQRVTQASVAV--DGAVISSIGKGLCVLVGITKDDTDMEYIRKILNTRLWWKTSVKDAEVLCVSQFTLYGKGNKPDFHLAMSRDFYHTFLDKLKEAYD-KIKDGQFQAMMQVSLTNDGPVTLTIDS Ashgo11 MRV-VIQRVSQASVVV--ENKLISSIKTGYMLLVGISTEDTDIEKSRKVSGLRLFWKRSIKDIEVLSISQFTLIAKGTRPDFHEAQALEMYDRFLDLLRQELK-QVQDGEFGAMMSCSLTNEGPVTIIYDT Aspfu1 MKVAVIQRVKSASVTV--DEKLVSSIGRGLLVLAGVGKEDTDADTLQRVLKAKLWWKRNVQDIEVLCVSQFTLYGKGSKPDFHDAAARKLYEYFFRRLGEAYD-RVKNGVFQAMMDVELKNDGPVTIEINT Aurde31 MRA-VVQRVARASVTV--DSNVVSEIGRGFMVLVGVGREDTDIELLKKILALRAFWKKTIKDVAILSVSQFTLYARG-RPDFHSAAGRELYAAFLQHLGELYQ-RIKDGQFGAMMDVSLTNEGPVTFTLDT Batde5 MRA-VIQRVSSASVTV--DGTVVSRINNGLCILVG----DTEMDYMKKIMGLKVFWDANIKDIDVLCVSQFTLYAKGNKPDFHLGNVRDMYNRFLEKMRAAYE-KIKDGVFGAMMKVDIVNEGPVTIILDT Botbo1 MRA-IIQRVSSASVTV--DNEVISQIGKGLMVLVGIGKDDTDVENIKKILSVRAFWGASVTELEVLCVSQFTLFAKGSKPDFHSAMSRDMYASFLTRIGELYE-KIKDGKFGAMMSVALTNEGPVTLTLDS Botci1 MKA-ILQRVLSASVTV--DKQLISSIGKGILVFAAVAPGDTDAESLAKVLKMRLWWKHNVQDIEVLCVSQFTLLAKGSKPDFHGALARELYQLFVTKVQQGYE-RVKDGVFQAMMEVALVNDGPVTLEMST Caeel MKV-VLQRVTRAAVTV--GDEVVGSIGRGLCVLVGVHRDDTDMKYIRKILNLRVFWDKSVMDLEVLSVSQFTLYGKGNKLDFHTAMASKFYASFLEAMKKAYD-KIQDGKFAAMMSVDIVNDGPVTVTFDS Canalb1 ------------------------------MVLVGITTTDTDIAKLKKLLSLRVFWAKSIVDIEILSVSQFTLYGKGTKPDFHRAAAAELYNKLLEQLRAGLE-KVKDGEFGAMMDVALVNDGPVTIVWDT Cangl MRI-VIQKVSQAMVKV--DNEIVSQIAKGYMLLVGISTEDTDAQKLNKVLNLRLFWKHSIQDVEILSVSQFTLMAKGNKPDFHKAQAQELYNQFLDLLKTTLD-KVKDGQFGAMMSCSLTNEGPVTIILDS Capow MRA-VIQRVISASVTV--DAEVVGSVGRGLCVLVGIHKNDTDLELLRRILNAKLFWQLNVTEAGVLCVSQFTLYAKGKKPDFHSAMSREFYNDFLAEMRRQYD-RIQDGRFGAMMQVQLINDGPVTIIVDT Catan2 MRA-VIQCVSSASVTV--DSQVISSISRGLMVLVGLAHDDTDVDYIRKLLNSRLFWKKSAKDLEVLCVSQFTLYGKGNKPDFHASMAKETYAGFLEKLRNGYD-RIKDGQFQAMMQVALVNEGPITLTLDS Cioin MKA-IVQRVVKAGVTV--GEEQISSIGRGICVLVGISKDDGDTEYMRKILNLRIFWAKSVKEMEILCVSQFTLQCKGNKPDFHGAMSETFYKDFLEKLRQSYD-KIQDGKFGNHMQVHIQNDGPVTIELNS CocheC53 MRT-VLQRVKSASVTV--DGQLISSIGKGLLVLAAISKDDTDVEAMAKILKARLWWKSNVSDIEVLCVSQFTLLAKGNKPDFHQSAARTLYQAFFSKVKALYE-KVKDGLFAAMMDVALVNDGPVTIQIDT Coere1 MRA-VLQRVAQASVTV--GDRVVGAIGPGICVLVGICQEDTDMEYIKKIIGMRVFWKKSVQDKEILCVSQFTLYGKGMKPDFHQAMSRQVFDDLVVQLGKLYA-KIATGEFGAMMQVALVNDGPVTLQLDS Conco1 MRV-VIQKVKRASVTV--DSNIVGKINRGLCVLVGITHDDTDIDYMKKILNTRVFWTKSVKDLEVLSVSQFTLYVKGNKPDFHAAMSRDFYEKFLNKLKQEYE-KIQDGQFGAMMDVEIINDGPVTFPLDS Conpu1 MRA-VVQRVASASVAV--DGETISKISKGLMVLVGIGTDDTDVESLNKILGLRVFWKASVRDIEVLCVSQFTLMAKGNKPDFHRAMSRALYAVFLEKMRSSYS-KIQDGRFGAMMDVSLTNEGPVTLTLDT Copci MRA-VVQRVTSASVTV--DGEMVSQIGRGLMVLVGIGVDDNDIATLKKILSLRVFWKSSVKDIEILCVSQFTLFAKGNKPDFHRAMSKAMYARFLEQLGKQYG-RIKDGRFGAMMNVSLTNEGPVTFTLDS Croqu1 MKA-VIQRVLSASVQV--NGNRISEIERGLCVLIGIGTDDVDMDYISKILALRLFWSKNVKEIEVLCVSQFTLMAKGNKPDFHNAMSRELYAKLIEKMKLGYD-RIKDGEFGAMMQVQITNDGPVTIIVDS CryneH991 MKA-VLQRVINASVTV--DGKIISSIGKGLLVLVGIDRYDEDATQIKKILTARLWWKKNVKDIEVLCVSQFTLLAKGAKPDFHESMGNAFYSSFLKEIKTAYT-KIQDGQFGAMMQVSLTNDGPVTILLSS Crypa2 MKV-VLQRVLSASVTV--ERELVSSIGKGVLVFAAIAPGDTDAESMAKVLKLRLWWKKNVQDIEVLCVSQFTLLAKGNKPDFHGALAKELYQYFFTKVQEGYD-KVKNGVFQAMMEVALVNDGPVTLELTA Debha1 MRV-VIQKVKQASVVV--DDKIISSINKGLMILVGISTKDTDVTRLKKLLGLRIFWAKSLLDDSVLSVSQFTLYGKGTKPDFHKAAARSLYDELLNQLRIGLEERVKDGEFGAMMDVSLTNDGPVTIIWDT Dekbr2 MKV-VIQKVRNASVTV--DNKVISQIGQGLSLLIGIARTDTDVSKLNKILRLRIFWAKSVSDIEILCVSQFTLYGKGTKPDFHRAMAELLYLRLLEELRRGIS-SVQSGKFGAMMDVSLVNDGPVTIIWDT Dicdi MKA-IIQRVKSSSVTV--EGEVISEIKQGLMCLIGIGRDDTDAEYIRKILNLRLWWDRSVQQMEILFVSQFTLFAKGNKQSYHLAMSKQFYLDFLENAKKSYE-KIKDGRFGAMMDVQLINDGPVTIQLDS Dmel MRA-VIQRVKAAKVTV--LDELVSSIGPGLCVLVGIKASDTDVEYL------------------------------------------------------------------------------------- Enthi MRI-IVQRVLSGSVTKVESGEVVGKIGKGLLLYFGINEEDKDIDGANKVLKMKLWWSKSVMDMEVLVVSQFTLYANGTKPDFHKSMSHPFYDLVVKRFKELYD-KIQIGAFGQYMKISTEVDGPVNIIVDY Falba MKC-ILQRVTAASVTV--DGAIVGAIKEGVMVLIGLHHEDKDLDYISKILTTRVFWARSVTDAGVLSVSQFTLNCKGTRPDFHHAMARETYDLFLEKLRKAYGGHIANGIFGANMSVNIVNDGPVTITFDS Fomme1 ------------------------------MVLVGIGTDDTDMHQINKIISLRVFWKKSVKDIEILCVSQFTLMAKGNKPDFHRAMSRRLYASLLDRLGALYD-KIKDGKFGAMMNVSLTNEGPVTFTIDS Fusgr1 MKV-ILQRVLSASVTV--DKEMISSIGKGVLAFAAVAPGDTEADLMAKVLRMKLWWKKSVGDIEVLCVSQFTLLAKGAKPDFHGAAARRLYHYFVQKVKAGYE-RVKDGQFQAWMEVALVNDGPVTLELKN Galma1 MRA-IIQRVSSASVTV--NNEIVAQISNGLMVLVGIGSDDTDVATLKKILTLRVFWKASVKDIDILCVSQFTLLAKGNKPDFHNAMSRHLYGKFLDSLRKSYN-KIQDGVFGAMMSVGLTNEGPVTFTLDT Ganpr1 MRL-VLQRVSRASVTV--DGETVSSIGRGICVLVGIAQDDQDADVLKKLLDIRMWWAKGVRDIEVLCVSQFTLHAKGTKPDFSRAMAREFYETFLAKLRSLYE-KIKDGVFGAMMSVEIVNDGPVTLVIDS Gloin1 MRA-VLQRVLNASVTV--NTQ-VSSIDRGLCILLGIAFDDTDLEYMKKILKVRVFWSRSVKDAEILCVSQFTLYGK-NKPSFHNAMSKEMYSTFLNRLKQEYE-RIKDGVFGEKMIVNIVNDGPVTLELDS Hisca1 MKA-VLQRVTSASVTV--DKTLISSIGRGLLVFAAVGPDDTDAESLAKVLKLKIWWKRSVQDIEVLCVSQFTLLAKGNKPDFHHAAAKELYDHFYNKVGELYE-RVKNGVFQAMMEVGLVNDGPVTIQIDT Klula1 MRI-VLQKVSEASVTV--GSAVVSQIKHGYMLLVGIGTDDKDIDKLKKILTFRGFWKRNISEVEILCVSQFTLMAKGTKPDFHLAQANELYGQFMDKLKAGLD-KVQNGVFGAMMSCKLTNEGPVTIIFDS Lacbi2 MRA-VIQRVSSASVTV--DNEVVSRISKGLMVFIGIGSDDTDVVTLNKILSLRVFWRASVKDVDILCVSQFTLMAKGNKPDFHRAMSRQLYASFLEKLRKDYE-KVQDGRFGAMMSVSLTNEGPVTFTLDS Lenti61 MRA-IVQRVSSASVTV--DNEVISSIGRGLMVLVGIGRDDTDLENLKQILTLKVFWKKNVKDIEVLCVSQFTLFAKG-KPDFHRAMSRDLYGSFLKRMGELYA-KIQDGRFGAMMDVRLTNEGPVTFTLDS Malgl1 MRA-VLQRVKQASVHV--QGRQVSKIGPGILALIGVCQDDTHMDILKKILQLKLWWRTNVMELEVLCVSQFTLYAKGTRPDFHLSMAKPFYDAFLAKMRNMYD-KIHDGEFGAMMDVSLVNDGPVTISIDT Mellp23 MKA-VIQRVLAASVEV--DGHRISEIKRGLCVLIGIGADDVDMDYINKILNLRLFWAKNVKDIEVLCVSQFTLLAKGNKPDFHNAMSRVMYAELLELMKLSYE-RIKDGEFGAMMQVNIANDGPVTITLDS Mnele MKA-IVQKVTKASVTV--GERCTGSIGQGMCVLLGISTKDTEIEWMNKLVKLRIFWDADLLQCGILVVSQFTLQCKGNKPDFHNAMSEQMYNKFVQVLRSKIDTLVQEGEFGAFMQVHIQNDGPVTIPIDS Monbr ----------------------------------------------------------------------------------------------------------------------------------- Morel2 MRA-VLQRVLQASVEV--NGEQISKIRQGLCVLIGLSIDDTDLDFMKKLLSVRVFWAKSVVDIEILCVSQFTLYGKGSKPDFHLSMSKQMYHEFLNRLKKAYD-RIKDGEFGAMMLVNIANDGPVTLELDS Mucci2 MRA-VIQRVTKASVTV--DEKVVGSIQKGLCVLLGIGTDDTDVDYMNKILNVRVFWKKGVKDAELLCVSQFTLQGKGNKPDFHRAMAKAMYEQFLQKLGKSYS-KIQDGEFGAMMLVDIANDGPVTLELDS Mydma MRA-IVQKVTSASVSV--KNKLISSIGCGLCVFIGISRNDTDIDYMNKILNLKIFWKKSVKDKEILCVSQFTLHSKGNKLDFHLSMSKDFYNTFVKQLGIAFN-NVKDGVFGEYMQVNIQNDGPVTIQLDS Neucr2 MKA-ILQRVLSASVTV--DNQLVSSIGQGILVLAAVAPGDTEAEALSKVIKLKLWWKKNVQDIEVLCVSQFTLLAKGSKPDFHGALAKTLYDLFYKKVQEGYE-KVKNGVFQAMMQVALVNDGPVTLEVSA Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------- Pench1 MKL-VIQRVKSASVTV--DSELISSIGKGLLVFAGVGKEDTDAENLNKVLKAKFWWKKNVKDIEVLCVSQFTLYAKGNKPDFHDAAARKLYDFFYAKMGEGYD-RVKNGVFQAMMDVELKNDGPVTIEINT Phybl2 MRA-VLQRVTRASVTV--DHQVVGSIQKGICVLVGIATDDVDVDYMNKILNVRVFWKAGVKQAEILCVSQFTLQGKGNKPDFHRAMAKSMYELFLGKLGKAYA-KIQDGKFGEMMSVEIINDGPITLELDS Picst3 ------------------------------MLLVGISTKDSDVSKMKKLLSLRVFWSKSIVDVEILAVSQFTLYGKGTKPDFHKAAAHELYHMFLDQLKVGLDSKVKDGEFGAMMDVALVNDGPVTIVWDT Plicr1 MRA-VLQRVSSASVTV--NNDVISQISRGLMVLVGIGIDDTDVDLLNKILSLRVFWKSSVKDIEVLCVSQFTLMAKGNKPDFHRAMSRDLYAQFLVKMGELYD-KIKDGRFGAMMNVGLTNEGPITFTLDS Polpo MRA-VIQRVKQGSVTV--NNEVISSIGQGLVCLIGITHDDTDSDWL-------LWWDKSVKDMEVLFVSQFTLYAKGTKPDFHCAMSKQFYTQFLNDAKQNYE-LIKDGCFGAMMDVGIVNDGPVTIVLDS Pucgr2 MRA-VIQRVTSASVTV--NQTEISRIGKGLCVLIGIGTDDTEMSYISKILSLRLFWTKSVRDIEVLIVSQFTLMAKGNKPDFHNAMSKALYEELLKSLKSTYA-LIKEGQFGAMMNVNISNDGPVTIILDT Punst1 MRA-VIQRVTSASVTV--DNEVVSAISRGLVVLVGIGTDDTDVETLKKILSLRVFWKASVKDLDVLCVSQFTLMAKGNKPDFHRAMSRKLYASFLERMAQLYL-YVLDGRFGAMMNVSLTNEA-------- Rhior3 MKA-VVQRVAKASVTV--DNRVVGSIQKGLCILLGIGTDDTDVDYMNKILNIRVFWKKGVKDSELLCVSQFTLQGKGNKPDFHKAMAKMMYQQFMDKLGKAYS-KIQDGEFGAMMMVDISNDGPVTLQLDS Rhoto1 MRA-VIQRVKQASVTV--EGQCISQIGRGILCLVGIGANDTESQWLAKLLALKVFWKKSVVEAEILCVSQFTLQAKGAKPDFHGAKAKQMYEDFLQDLKTKYE-RIKDGQFQAMMDVQLVNDGPVTLILDS Rozal11 ----------------------------------------------------------------------------------------------------------------------------------- Sacce1 MKI-VLQKVSQASVVV--DSKVISSIKHGYMLLVGISIDDSEIDKLKKVLSLRIFWKKNIKEAEILSVSQFTLMAKGTKPDFHLAQAKELYEEFLKLLRSDLE-KVKDGEFGAMMSCSLTNEGPVTIILDS Salro MRA-VVQRVVRASVAV--GDEVVSQIDRGLCVLVGITHDDTDIDYIKKILTLRLFWKKSAQDLDVLCVSQFTLYAKA-KPDFHMAMSKEFYESFLHKIRSDYD-KVKDGEFGAYMKVDIVNDGPVTIMLDS Schco3 MRA-IIQRVSSASVTV--DNEVVSRISKGLMVLVGIGTDDSDAATINKILNLRVFWKSSVKDIDILCVSQFTLLGKGNKPDFHKAMSRVFYSSFLESLGKAYD-KIKDGKFGAMMSVSLCNEGPVTFTIDS Schpo1 MKA-VIQRVLNASVSV--DDKIVSAIQQGYCILLGVGSDDTDVTKLNKILKLKLFWKSTIADIEILCVSQFTLHAKGAKPDFHRSMAIELYEQVVKTLGESLD-KIKKGVFGAMMNVQLVNNGPVTILYDT Sorma MKA-ILQRVLSASVTV--DNQLVSSIGQGILVLAAVAPGDTEAEALSKVLKLKLWPHG--------VVSQFTLLAKGSKPDFHGALAKTLYDLFYRKVQEGYD-RVKNGVFQAMMQVALVNDGPVTLEVSA Sphar -----------------------------------MGTSET--------------------------------------PNFSSSMAEPLYHSMIEELKQLYA-KIQDGMFGAMMDVALINDGPVTIQIDS Spipu1 MRA-ILQRVSSASVTV--NGEIVGKIGKGICVLIGISGDDEDVNWMKKLTSVRVFWTKSVKDLEILSVSQFTLYAKGSKPDFHLAMSKDMYTTFLEKLKAAYE-RVQDGVFGAMMQVNILNDGPVTLILDS Sporo1 MRA-VLQRCTSASVTV--DGKVISSIGRGVLCLIGIGTNDTEAKWLSKLLGMRLFWKHSVVDAEVLCVSQFTLMAKGSKPDFHAAMSKQMYLDFLDDLRSKYD-KIQDGEFGAMMDVQLVNDGPVTLILDS Stehi1 MRA-VVQRVLSASVTV--DGETISHISRGLMVLVGIGTDDTDAELLKKILSLRIFWKASVKDIEVLCVSQFTLMAKGSKPDFHRAMSSELYSVFLGKMREAYD-KIKDGKFGAMMNVSLTNEGPVTFTLDT Tapde11 ----------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------- Treme1 ---------------V--DGPIISSFGRGFVFLVGLDKWKSDTKTMKKILSIKLFWKRDVRDIDILCVSQFTLFAKGSKPDFHESMGKSAYTSFLEHLRNSYE-KVQDGKFGAMMQVSLVNDGPVTINLDT Trire2 MKA-IIQRVLSASVTV--EKELVSSIGRGVLVFAAVAPGDTEADSLNKVVKMKLWWKRSVTDIEVLCVSQFTLLAKGTKPDFHGAAASRLYRYFVQRVKDMYD-RVKDGKFQAMMEVALVNDGPTIPRITS Umbra1 MRA-VLQRVARASVSV--DEQVVSSIGKGICVLVGISVDDNDIDYMRKLLTLRVFWKKSVQDMELLCVSQFTLFAKGSKPDFHSSMANEMYKKFLDKLGAAYE-KIKDGVFGAMMMVEILNDGPVTIELDS Ustma22 MRA-VLQRVKGATVHV--DGKLVSKIGPGIVALIGISTEDTEIVPLNKILNTKLWWKRSVVELEVLCVSQFTLFAKGTKPDFHRAMARVIYEALLHKLGDSYE-RIKDGAFGEMMDVSLTNDGPVTILLDT Walse1 MKV-VIQKVSKASVSV--NQKIVNSIENGLCLLVGLGVDDNDLKWTNKVLGLRLFWTKSVRDVEILSISQFTLQSKGTKPDFHKAMARKMYNNFLTSLKTSYN-RIKDGIFAEMMDVNINNQGPITILIDS Zygro1 MRI-VLQKVSQAAVTV--ESRVVSSIKNGYFLLVGISTEDTDVEKLNKVLSIRIFWKRNIKDAEILSVSQFTLMAKGTKPDLHMAQAKELYDHFLTLLRNGLD-RVQDGEFGAMMSCSLTNEGPVTITLDT [Cluster2129.fasta_al_trimmed; alignment length = 239] Allma1 KQTELQK-KRKLLKKYLRRGDLERL-REEERRQQQLSADEVNRRLRARGHPIRLFGESDRDRVWRMRRIEAEARNEYAQQLAASLLATDPD-ALRRMLDTWEAILARPD--HVKRSTAGKHEATQAKDNLKPFFKLLKRKAVETDVMAKIADILRYVQ-Q-REYVKAYDAYLQLSIGNAPWPIGVTM-VGIHERSAREKIFASQVAHVLNDETQRKWIQSIKRIMSFFQLHFPPDDPTK Ashgo11 ----------------------------------------------------------------------------IEALIK----------RIHTLIRRWEETE--------------VYLPEELKRHLFPLLVQLRRGSLQKDLLTTLASLLYHLQ-Q-EEFAQAEQCYLDLSLGKVAWPIGVAG-VGIHSAHDTARRIGTTRANVMKDEETRDWILQVKRLITFSIKAEPDEDDED Aspfu1 MAKEISK-AKSS-KKYVRRAELEAA-RIAAQREREIPDEELNQKLRDLKEPICLFGENHVARLRRYRRLVRRSDGPIPTTLE-----------FNMVLLEWERALRRDA--SVKQSLTGRQAYNQSRENLKPLFRKFEKNDIDDNLLEPIMEIVHKAQ-L-RRYVDANDAYLRVSIGKAAWPIGVTM-VGIHERSAREKLHQSDQAHILSDEITRKFLQSIKRCLSFAQTRWPPDDQLQ Aurde31 LKSEIAN-KRKALAKYMRRGDLDRL-REEERKRREISNEDAIRRLRQKGQPIRLFGETDKERRLRLRALELIEQNDFKKALELDLVKTDPN-RLKKKLKEWEEALERPD--NIKQSTQGKLAAAQSAQYLKPMFKILRSRSLPPDMLLRISEIVHYMQ-K-RQYQKANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISTDQVAHVLNDEVSRKYIQTLKRILTFAQTKYPPEDVSQ Batde5 TKA--------------------------------LDEDEIIRRLRARDQPIRLFGESNQQRLGRLRKVESTERNDFKDLLQLELLQADRD-TIKRLLLEWAKELSRPD--EQRRTTQGKLQAAQAGEYLKPFFRGLKKRDLAEDILARVTEICYYTQ-Q-REYQQANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSSQIAHALNDETQRKWIQSIKRLMTFAQTKWPPEDLSK Botbo1 LKAEIAQ-KRKVINKYMRRGELEKL-KEETRKEREISNEDAVRRLRAKGQPIRLFGETDKERRLRLRALELIELNDFRKVMELGLVKSDPD-KLKKVLKEWGESMERPD--HIKRTTQGKRAAAQSAEYLKPLFKSLRQRNLPSDVLARMAEIVHYMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISSDQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPDDLSQ Botci1 MSKEISK-KSESSKKYMKRSEIEAE-RQAKEAEREIPDEELVLKLREMGHPAKLFAETHKQRLRRFRKLGVV-TGPIPTTLV-----------FTMVLQEWEHALKEKR-----DTFASKAAYNQSKDNMTPLFRKFEKGDLDEDILGPVVEIVKAAQ-E-KRYVDANDGYLRLSIGKAAWPIGVTM-VGIHERSAREKLHETDKGHVMGDEITRKFLQSIKRCLSFAQVRWPPEDIRQ Caeel LLAEMAK-KRKAVAKFVKGADLEMK-RNQERKQQETPMSEIQTRLRQRNHPIMLFGETDIDVRKRLHQLELAQENELQTAMKSTLLSVDDDLKCRYILARWAKDLDRPL--DVKKTAQGMHEAAQTMMHLKSLMTSMERYNCNNDIRHHLAKICRLLVID-RNYLEANNAYMEMAIGNAPWPVGVTR-SGIHQRPGSAKSYVSNIAHVLNDETQRKYIQAFKRLMTKMQEYFPPSKSVE Canalb1 LSNEINK-KRK--GRKRSKVSTTA--------KEP-SEEQLDTKLSQFGEL-----DTSLSKSEKARKLQLLLNTKYKAWLD----------KIKQLIKQWQECD--DDQE-------------ETKKSIVKLLYKLRSHKLSLDMLISLSTIVYYIQ-Q-NEFNKANESYMKLSIGNVCWPIGVVN-VGIHARSAASKITGASNSNIMLSESTRRWIISIKRLISFKER---ARD--- Cangl MATE---------------------------KP----------------------------------------DERIQAVIE----------KLHKLLDTWALEQ--------------EGGNDDTKRGIYPLLVSLRKARLPSDQLVSLATVLYHLQ-QYEHMQRSLESYMKLSLGNVAWPIGVTQ-VGIHERKIQR--QDARNANVMTDEQTRLWITNVKRLLTHMEQRK------- Capow LAAELER-KRKLLKKYFRKADLDQR-KLELRAASALPQPEVIRRLRERDHPIRLFGETNEDVLERLRQLEIVERNDFMDAIGRGLD--END-ILKYLLKLWETELERSE--EEKRAMAGKLLSAQTLSYLKPLFRLIKQKAVPDDIAPFLIRIVRFML-E-REYSQAGDSYMKMAIGNAPWPMGVTM-VGIHARGGREKISAGNIAHVLNDETARKYIQALKRLMTVCQRRFPPSKSLE Catan2 KKTEAGR-KRKLLSKYLSRGEIERL-AA--ERQREIPSDEVIRRLRARGQPIRLFGESDAERIVRMRNIEADARNEYARQLASKLLATNPD-KLKRMLEDWEQELTRPD--HIRRSVQGKHEATQTKDNLKPFFKLLKRKAVDNDVMEKIADILKNVQ-R-REYVRANDHYLQLSIGNAPWPIGVTM-VGIHERSAREKISSHQVAHALNDETQRKWIQSVKRIMTFAQHKYPPDDPAK Cioin LKAEVDR-KRKVIKKYFKRGDLERK-EREEEAKH-LSRQEVVKRLRERSEPIRLFAESDYEAFQRLRKLEIMARNDFKVALDKNLGRGNDN-EMKFLLKCWAKELNEIP--EENKKGKWKIQSAQTQTYLSPLFNQLKNKTVATDILEYLSGIIKHIL-T-RDYVKASAIYLQMAIGNAPWPIGVTM-VGIHARTGREKIFSQQIAHVLNDETQRKFIQGLKRIMTACQRIFPPSKSLE CocheC53 MSAHIKK-GKEAAKKYLKRSEIEAQ-RQAAEKARLIEDGELIAKLRALDEPARIFGETHKQRLKRYKKRVGADDGPIPTTLQ-----------FTMVLKEWDVTLRRDT--EVKESYQGKQAYAQARENMRPLFKKLEKFDLPDSIIEPVVEIVHAAQ-E-RRYVDANDGYLRLSIGKAAWPIGVTM-VGIHERSAREKLHESDKAHIMSDEITRKYLQSIKRCLSFAQTRWPPTDQLQ Coere1 -----------------------------------ISSEEVVKRLRARSEPIRLFGESDEQRRRRLRHLELSEQNEFRRMMALELLRTDMD-RFKRLLYEWGDYLSRPE--DERRSAEGKMAAAQSAEYLKPLFRSLKQRKLQADVMARITEIARSTL-D-REYMNANDAYLQLSVGNAPWPIGITQ-VGIHSRAARENISASKVAHVLNDETQRKWIQSIKRLVRFAQTKYPPADLSK Conco1 LKSEISK-KKAELIKYVKRSELERI-REEELKDQELPEEEVIRRLRAKGQPIRLFAETDRSRQIRLRALELIERNDFMQALSTELMSSNID-RFKRTIKEWESDMNRPE--EIKRSTAGINAAAQTAQYLKPFFRNLKNKDLPQDVLIRIIEICNFVQ-E-REYMKANDSYLKLSIGNAAWPIGVTM-VGIHERSAREKISAGSVAHVLNDESQRKWIQSIKRIMTYLQRKYPPSDFSK Conpu1 LKAEIAA-KRKNINKYVRRGDLDRA-QEEQRKEQEISNEETIRRLRARSQPIRLFAESDKDRRLRLRALELIEQNDFKKALELNLIKTDPD-KLKRTLKEWEEAMERPE--HVKRTHQGKLAAAQSAEYLKPLFKTLRQRALPPDMLARIAEIVHHMQ-K-RQYQRANDAYLRLSIGNAPWPIGVTM-VGIHERSAREKISSDQVAHVLNDEVSRKYIQSLKRLLTFAQTKYPPEDVSQ Copci LKAEIAA-KRKVLTKYMRRGDIERI-KEEQRKAEEISNEETIRRLRAKGQPIRLFGESDKDRRLRLRALELIEQNDFKKALELDLIKTDPD-RLKRILKEWEESMERPE--EVKRTRQGKLAAAQSAEYLKPLFKQLRSRSLPSDMLARIAEIVHFTQ-K-RQYQRANDAYLRLSIGNAPWPIGVTM-VGIHERSAREKISADQVAHVLNDEVSRKYIQSLKRLITFSQTRYPPDDISQ Croqu1 LKAQIES-KRRA-KKYMRKGDLEKA-KLEA--ERAISNEEAVRRLRSRGQPIRLFGESDKERRLRLRALQLIERNELMRALELELIKTDPR-KLKRVLKEWEQSMERPD--HIRRSTQGKLVAAQSAEYLKPLFKSLRKRELAPDVLQAVAEIVHHMQ-T-REYIKANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSNNVAHVLNDEVSRKYIQSLKRILTFAQTKRPPDDLAR CryneH991 LLAEISA-KRKALKKYMRRADIERM-REEERRKKEISPEECIRRLRQKGQPIRLFGESDKDRRLRLRALELLERNDFKKALELKLIKTDPN-KLKGVLKEWEEWMNRPE--EIRRSTQGKLAAAQSAQSLKPLFRSLRSRDLAPDVLRLLAEIVHHMQ-S-RSYQKANDAYLRLSIGNAAWPIGVTS-VGIHERSAREKIGQDNIAHVLNDEVTRKYIQAVKRLLTFSQTIRPPEDVSQ Crypa2 --------------------------------------------------PA-----------------------------------------FTMVLREWEAALREQRGEDGADTGAARQAYNQCKQAMTPLFRRLERGDIDQIVLESIVAIVRAAQ-D-RRYLDANDEYLRLSIGKAAWPIGVTM-VGIHERSAREKLHSGEKGHVMGDEATRKYLQSIKRCLTFAQVRWPPEDVRQ Debha1 LSKEIDK-KRKL-KNKKVKAEDEV----------NISDEQLDAKL---EQLGER-CNTGSTKLDKIRKVEVLLNEVYRIQLE----------QVKYMVKEWENDVIRDDEEREGEEESVARQSSDTKKDLVRLLYKLRTQKLTDSMLTSLCTIMYYLQ-V-RDYRRANESYMKLSIGNVAWPIGVKG-VGIHERSAALKITGENKANIMLDDKTRRWITAIKRLISFAERKWP------ Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi LKEQLEK-KRKEAKKYKTRGEID---KELKKKEEELPDIVVIQRLRERSQPITYFGETSIDRAMRLKKLEENDDNEFANILKLERLRIDSS-KLKGLLNDWITNLNRSD--DEKKSRQGKIAEAQCKSHIQPLFTSLREKTLSIDILEHINEIVEFCK-S-REYVRANDEYLQMAIGNAPWPMGVTM-VGIHERSSREKIFSNQVAHVLNDEMQRKYIQAVKRLMTFCQTQYP-TAPSR Dmel LKAEIAR-KRKLLKKYFRRGDLNAK-NTEELQKV-LPRTEVIRRLRERGEPILIFGETEPEAFDRLRQCEISQRNDFQEAMEANMGR-NKD-YLTFLLKLWNDQINYSK--HEKMSTKVKMTRVQTKEYVKPLFRKLKHHTLPEDILDSLRDICKHLL-N-RNYITASDAYLEMAIGNAPWPIGVTM-VGIHARTGREKIFSKNVAHVMNDETQRKYIQGLKRLMTKCQEYFPPSKCVE Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba LDEAIMS-KSTRAMRFRRRGELNKA-----EKKSPLSTREVVRRLRRLGEPIRLFGESDKERETRLRELETTGRNLTRSTMADEVYRRSTN-RLKFLTNMWDQRLSRPD--YEQRSRQGRDDRRDTKLHIQPLLRHLRRRTLEQDMLQHLTRICDFLQ-R-REYRNALDTYYLMSIGNAPWPMGVTM-VGIHERSAREKISSNQVAHVLNDERTRRWIHCLKRLMTLTQDIFPPEDLVQ Fomme1 ----------------MRRGELEKL-KAEQRREKEISNEDAIRRLRAKGQPIRLFGETDRERRLRLRALELIEQNDFKKALEPDLIKTDPD-KLKKTLREWGEAMERPE--HIKRSTQGKLAAAQSAQYLKPLFKSLRSRNLPADVLARIAEIVYYMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKIATDQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPDDLTQ Fusgr1 MNKELSK-SKKGSKKYLKRSEIEAQ-RKEAEAERQIPEEELVEKLRAIGEPVALFGESHAARVRRYRRLTIV-KGPIPTTLE-----------FTMVLTEYERAMAEKR-----DTTAGKTAYNQTRENMKPLFRKFEQGELDDDILKPVIEIVQALQ-E-RRYVDANDGYLRLSIGNAAWPIGVTM-VGIHERSAREKLHDGEKGHVMGDEVTRKYLQSIKRCLTFAQVRWPPTDLRQ Galma1 LKAEIAS-KRKALSKYMRRGDIERL-REERQKAREVSNEETVRRLRAKGQPVRLFGELDKDRRLRLRALELIEQNDFKKALELNLLKTDPD-KLKRTLKEWEEAMERPE--HIKRTTQGKLAAAQSAEYLKPLFKTLRSRSLPPDMLVRMAEIVHHMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISADQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPADISQ Ganpr1 LNAEIAR-KRKAAKKYKRRGDIEAE-REAERKAEEISSAEVVRRLRARGEPIRLFGESDAARTDRLRLVESQERNEFMRALEVDLLMKDPE-RFRRLFMAWEKDLSRSD--EDKRSNEGKKREAQTTDYMRPFFKALSSKNLDADVVARISEIADWLQ-K-REYQRANNAYLTLSIGNAPWPIGVTM-VGIHERSAREKIFAAQVAHVLNDETTRKWIQSLKRLMSWMQDKYPPADLSK Gloin1 LKAEIEN-KRKFLKKYVRRSDVEKK-REQQEKKREISPEEVVRRLRAKGQPIRLFGESDKDRKTRLRALELIE---------IELLEKDPD-KLRRLIREWEQEMNRPD--HVKRSVQGKLSAAQTNEYMQPFFRTLKKKSIEPDVLARVTEITHYMQ-K-REYMNANDAYLRLSIGNAPWPIGI-----IHERSAREKIFSAQVAHVLNDETTRKWIQSIKRLMTFCQSKYPPEDNSQ Hisca1 MAKEISK-AKAPEKPYVKRSDTEAA-RLAARKERELGEDEVIDKLRAAGEPAILFGESHRGRVKRYRRLLQRSERPIATTLV-----------FTMIFKEWEIALKRDD--DVKNSYQGKQAYNQSRENIRPLFRRFENGDLEESILEPVVEIVRSAQ-D-RRYVDANDGYLRLSIGKAAWPIGVTM-VGIHERSAREKLHQSDKAHIMSDEITRKFLQSIKRCLTFAQVRWPPDDQLQ Klula1 ----------------------------------------------------------------------------MSHAVE----------SIHEILKEWETQE--------------EYTVVRVKVALFPLLVALRKQELGQLQLSQLARVLDAIV-D-EDYVRAKQEYLTLSIGKGKFPIGLTN-VGIHERKQQL--QGSKAENMVLDD----WCVNIKRLVNFKQWTSSA----- Lacbi2 ----------------MRRGDIERL-KQEQEAA--ISNEETIRRLRAKSQPIRLFGESDKDRRLRLRALELIEQNDFKKALELALIKTDPD-KLKRTLKEWGEAMERPD--NVKRTTQGKLAAAQSAEYLKPLFKTLRSRSLPQDMLARMAEIVHHMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISADQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPEDISQ Lenti61 LKAEIAN-KRKALTKYMRRGELERL-KEEQRKVREISNEETIRRLRAKGQPIRLFGESDKERRLRLRALELIEQNDFKKALELELVKTDPD-KLKRALKEWEQWMDRPD--HIKRTTQGKLAAAQSAEYLKPLFKLLRTRNLPPDVLARVAEIVHHMQ-K-RQYSKANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISTDQVAHVLNDEVSRKYIQSLKRILTFAQTKYPPEDVTQ Malgl1 ------------------------M----------ISDDDAIQRLRQKGEPIHLFGETSRERRMRLRSLELSEHNDSRRFMRLKLMWTNPA-RIKGLLADWELALKRPE--DVRHSAQGRQLSAQTAEYIKPLLKALRRRSLEPDVLLRIAEIVHYMQ-Q-REYRKANDSYLQLSIGNAPWPIGITM-AG------------------------------------------------- Mellp23 LKAQIES-KRKL-KKYMRKGDIEKA-KLEA--EREISNEEAVRRLRSRGQPIRLFGESDKERRLRLRALQLIERNELMRALELELIKTDPR-KLKRVLKEWEQSMERPD--HIRRSTQGKLVAAQSAEYLKPLFKSLRKRDLAPDVLQAVAEIVHNMQ-T-REYIKANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSNNVAHVLNDEVSRKYIQSLKRILTFAQTKRPPDDLAR Mnele LKAELAR-KKALLKSYVKRSEIDKY-ETERYER--LEEAEVIKRLRERGEPIRLFGETPSETYQRLRSMEMQEQTDFKSAMEKGIS--DPD-AYRWLFDVYEQTGRKYR--ENEGDLAVKLERAQAETYIRPLFRTLKKKTLDETLLRSFGEIAGALL-E-RNYIGANDVYLRTAIGNAAWPIGVTM-VGIHARTGREKLFAHNVAHVLNDEYQRKYLQAIKRLITFAQRHFPPSKCVE Monbr VRAEISR-KREDL----------------------------------------LITEDLIDTRRRLQELELEERNELKEALELQLGKD-DS-KLRHMLTQWGSDLHRDD--ELKQSSEGRLATAQTEGYLKPLFKMLKTKQVSFDVLFALREIVEAML-H-RDYISANDAYLRLAIGNAAWPIGVTN-VGIHSRTGRERIFSQKIAHVLNDETQRKYIHGIKRLMTFAQKRYPPSKCLE Morel2 IEAALAK-KRAAVKKYIRKGDLEKQ-REQERKAKEIAPEEVVRRLRARGHPIRLFAETDQARKIRLRALELVERNDFMRAMEVDLIQKDMD-KFKRLLREWERDLQRPD--ELKRSTPGKLATAQSAEYLRPFFKSLRQKSLEPDVLMRITEIAELMI-K-REHMAANDAYLKLSIGNAPWPIGVTM-VGIHERSGREKIFSAQVAHVLNDETSRKWIQSIKRIMTFAEKKYPRL---- Mucci2 -----------------------------------ISREECVRRLRAMGQPIRLFAETDKQCKVRLRALELMNRNEFMKTLELELISKDID-RFAHTLEEWEEYMARPE--EEKRTGPGKRAAVQAAEYIKPLMRQLKKKTLEPDVLARVAEIAQRMQ-V-RLYRDAQDAYLQLSIGNAPWPIGVTM-VGIHERSAREKISSSQVAHVLNDEASRKWIQSVKRLMTFAQTKYPPYTLSQ Mydma LLAELDR-KRKQLKTYFKRGDLSKV-QAEERKQKNIEKSELCRRLRDLKEPIKLFGESHEDTCQRLRLIEMISRNDFKAALDQNIEKGNMQ-QLKHLSYLWGVDLKREL--HEKISISGKLSSAQTMAYLKPLFRKLRSQSLTADILNALTGIVQNLI-H-REYVKASDLYLQMAIGNAPWPIGVTN-PGIHARTGREKISTALVAHVLNDETQRKYIQALKRLMTFCQKKYTPSKCVE Neucr2 MSKEIAK-AKAAGPKFISRREAEAQ-RQAAEEERALPDDELTSKLRALGEPAFLFGESHLSRLRRYRKAAGLGMGPITTSLL-----------FNMVLREWELALKEDN----ADTFAGQAARNQSKETMRPLFRKFEKGDLEKDILEAIVEIVRAAQ-E-RRYVDANDGYLRLSIGKAAWPIGVTM-VGIHERSAREKLHDGERGHIMGGEVTRKYLQSIKRCLTFAQVRWPPEDIRQ Orpsp11 IDEEISK-KRKLIKKYIRRGDIENL-EKKKKKEKEISQDEVIKRLRSHGEPIRYFGETDQERIVRLRHLEAAEQNEFMHAMELELIQKDID-KFKRLLDEWEDDLKRSE--EVKRSYKGKRETAQTRDYLKPFFKELKHKTLQADVLARVSEIAQFMQ-E-REYMKANESYLQLSIGNAPWPIGVTM-VGIHERS-------------------------------------------- Pench1 MSKEISK-AKGSDKKYMRRGDVEAA-RIEAAREREIEEEELTAKLREMNAPITLFGEDYRARLRRYRRLVQRADGPIPTTLE-----------FNMVLSEWELALKRDI--SVRESFQGKQAFNQSRENMTPLFRLFEKSDLEDGLLEPIVEIVHKAQ-Q-RRYVDANDAYLRVSIGKAAWPIGVTM-VGIHERSAREKLHQSDQAHILSDEITRKYLQSIKRCLSFAQVRWPPEDQLQ Phybl2 -----------------------------------ISRQEVVRRLRAKGQPIRLFAETDKQCRIRLRALELMERNDFMRQLGLGLLQADRD-RLAYTQQEWADFMQRPE--EEKRSTQGKRAAVQTAEYIKPLLKQLKKRSLEPDILARVAEITHHMQ-N-RRYRDAQDSYLQLSIGNAPWPIGVTM-VGIHERSAREKIFSSQVAHVLNDETSRKWIQSVKRLMTFAQSKYPPDTLSQ Picst3 ISSEISK-KRK--KLKRSKNRDELD-----KQLENITDAQLNEKLAEFDKLTQE-ENL--TKLEKIKKLQFLVNEKYKTIIE----------IIKDMIRNWEDSI---------SEYQTAVQKKETKRDIVKLLYKLRSHKLNDDMLTSLTTIVFYLQ-S-HDFRRANESYMKLSIGNVAWPIGVQN-VGIHARSASLKIAGATKANIMVDDKTRRWITAIKRIITATER---S----- Plicr1 LKAEIAN-KRKALTKYMRRGDIEKL-KEEQRKEKEVSNEETVRRLRIKGQPIRLFGESDKDRRLRLRALELIEQNDFKKALELALIKSDPD-KLKRTLKEWEESMERPE--HIKRSTQGKLAAAQSAENLKPLFKALRSRSLPSDVLSRMAEIVHHMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISADQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPADISQ Polpo LKEQLEK-KRKEAKKYKTRGEIE---KENLKKEEELPKEQVVRKLRERGQPITYFGETDYMRAERLRLLEENEDNEFQNLLK---LKEESK-KLWKLLKEWKEHLARPE--EEVRTPQGNKAKAQCNIHIKPLFAQLKSKSLPDDLLQHIYKIVEFCK-E-REYSKANSQYMEMSIGNAPWPMGVTM-VGIHDRSSREKISSSQVAHVLNDETQRKFIQGIKRLMTFCQTKYP-NNPSK Pucgr2 LKAEIEL-KRKS-KKYMRKGDL--A-KLEA--ERQISNEEAVRRLRNKGQPIRLFGESDKERRLRLRALQLIERNELMQALELNLIKTEPR-KLKRVLKEWEQSMERPD--HIRRSAQGKLVAAQSAEYLKPLFKSLRKRELAPDVLQAVAEIVHHMQ-T-REYIRANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSNNVAHVLNDEVSRKYIQSLKRILTFAQTKRPPDDLAR Punst1 LKAEIAA-KRKALTKYLRRGEVERL-REEQRKEKEISAEETVRRLRAKGQPIRLFGESDKERRLRLRALELIEQNDFRKALELGLVKTDPK-KLKRMLKDWEEAMERPE--SVKRTHQGKLAAAQSAEYLKPLFKILRQRELPDDVLARLAEIVHYTQ-K-RQYQKANDAYLRLSIGNAPWPIGVTM-VGIHERSAREKISADQVAHVLNDEVSRKYIQSLKRLITFSQTKYPPEDVSQ Rhior3 -----------------------------------------------------------------------------MKTLEIELISSDID-RFAYTLEEWEEYMARPE--EEKRSVPGKRAAVQAAEYIKPLMRQLKKGTLEPDVLARVAEIAQRMQ-K-RLYRDAQDAYLQLSIGNAPWPIGVTM-VGIHERSAREKISSSQVAHVLNDETSRKWIQSVKRLMTFAQTKYPPYTLSQ Rhoto1 LKQEIAS-KKRQLKKYLKRSEIERL-REEEAREREISNDEAIRRLRQKGQPIRLFGESDKDRRLRLRALELLDRNEFQRALELDLVRTNPH-KLKRVLKEWEQSLDRPE--SVKRSAQGKIAAATSAEYLKPLFKSLRKRQLEADVLRNIAEITHYMQ-T-REYLRANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSNNVAHVLNDETSRKYIQSLKRLLTFAQAVRPPDDVSQ Rozal11 LQAEIEK-KRKLLKKYVKLSELEKL-REKD-----LKEEEIISRLRELDEPIRLFGETDFDRLKRLEERENSS-RELKNLIEAELMTEETT-KCKRLLLEWKYDLRMPE--EEKESKDGKHKFFQAEEYIAPFFERMRDNKLAKDVLSNIAQIFYSLK-E-KDYVKASFAYLLLSLGNAAWPMGVMGPINLNERHARDLIETHQIAHVLNDEAQRKWIQTIKRLITYAENKYPPK---- Sacce1 LKGEISK-KKK--SKGVQPPCTEK------FQPHE-SDNQSDDIRTTISKL----------------------PERIQEAIA----------KIHEILSRWKASL--------------AYHPEDTKKALFPLLLQLRRNQLAPDLLISLATVLYHLQ-QPKEINLAVQSYMKLSIGNVAWPIGVTS-VGIHARSAHSKIQGGRNANIMIDERTRLWITSIKRLITFEEWYTSLA---- Salro LLAEIAR-KKKELQKFVRRRDIEKR-MEERKKAAQIPMTEVRKRLRAMGQPVLMFGEDEIHVRRRLRNCEIQSRNEMQDALHKRLGKESDA-TFKFLLELWGKDLDRPI--EIRQSSQGKRASATTAQNMKPLFKKLKKKDLPDDILFNLREIALSIM-K-REYIQANDAYLRMSIGNAPWPIGVTN-VGIHSRTGREKISAHNIAHVLNDEMQRKYIQGLKRLMTFAQKRYPPSKCLE Schco3 LKAEIAT-KRKAISKYMRRGDLERL-REQEKKAAEISIEETIRRLRQKGQPIRLFGETDRDRRLRLRALELIEQNDFRKALELNLIKTDPD-KLKRTLKEWEEAMDRPE--DVKRTTQGKLAAAQSAEYLKPLFRQLRSRNLPPDVLARIAEIVHFMQ-T-RQYQKANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISSDQVAHVLNDEVSRKYIQSLKRLLTFSQTKYPPDDVSQ Schpo1 LKEEIER-KRRQLKKAFRRGDWEKE-REKKKQQKDLTLTEIIAKLREMKEPIRLFGESEEATIQRYYSLLKYK-------------------KLQHGIRIWDNFLSKSI--NSFESSESQMQLKQAKQDLDVLIQLIVDEALNDDIFKSIAEICYRCQ-K-HEFVKANDMYLRLTIGNAPWPIGVTM-VGIHERSAHQRLQANPSSNILKDEKKRKCLQALKRFITFQERESSPEYTD- Sorma MSKEIAK-AKGTTPKFISRREAEAQ-RQAAEEERAIPDDELTTKLRGLGEPACLFGETHASRLRRYRKAAGLGTGPITTSLL-----------FNMVLREWEIALKEDN----ADTFSGQAARNQSKETMRPLFRKIRK----------------PAT-S-R---------------KISW--------------------------------------------------------RR Sphar MKAELEA-QKQKVKSWMKKSELKAN-EANEKRKKEMAPKEVVRQLRDRNEPIRLFGETDTMRMHRLEYLKTHERNDFMEAIDEDVTKKQID-SVQYLLMKWEDDLNKDI--NDKRTAIGRKESAQTCSYIEPMQAQLKKNSLGEDIMPLLTEVFKSIY-E-REYIYAADMYLRLAIGNAAWPIGVTQ-VGIHSRTGREKIFSQHVAHVLNDEEQRKYIQALKRLMTYAQKRFPPSKCLE Spipu1 IKAELEK-KKAALKKYIKRGELEKR-REEEREEQKIAESDLVRRFRARDQPIRLFGETDKQRIRRLRKLEASERNDFRAAMALELLQSDRD-KFKRLLREWDKSLARPE--DVKRSVQGRLQAAQTAEYMKPFFKQLKKRALEPDVLARVCEIAQLMQ-Q-REYLQANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKIFSSQVAHVLNDEAQRKWIQSIKRLMTFAQTKWPPDDHAK Sporo1 ------------------------------------------------------------------------------------------------VLKEWEQSLDRPE--SVKRSTQGKVAAATSSEYLKPLFKQLRNRDLADDVLLAIAEITFYMQ-T-REYLRANDAYLRLSIGNAPWPIGVTM-VGIHERSGREKIFSNNIAHALNDETSRKYIQSLKRLLTFAQAVRPPADVSQ Stehi1 LKAEIAS-KRKALNKYMRRGDLERLNKEEERKAREISNEETVRRLRAKSQPIRLFGESDKERRLRLRALELIE-NDFRKALELELLKTDPD-RLKRALKEWEESLDRPD--NIKRSTQGKLAAAQSAEYLKPLFKLIRSRSLPPDMLARISEIVHHMQ-K-RQYQRANDSYLRLSIGNAPWPIGVTM-VGIHERSAREKISSDQVAHVLNDEVSRKYIQSLKRLLTFAQTKYPPEDVSQ Tapde11 LSGEINKLKRKAPRKYIKRSEIEAS-RQEERKQQE----AIQADLRALKQPIRYFGEEPADIKKRLDQYKARQ-NSTNALLQLSLLKTEEEEKLKFYIKQWDHDVSSSP--DGGESSQ----VAQAKEHLARLLLRLKTGNLPIDILTNLASVVSSLQ-Q-ADFTGANRAYLQMSIGKATWPVGVTS-VGIHERAQRERQHKKLDAHILADETTRQWLQSLKRLITYREKRAA------ Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LLAEINS-KRKALKKYLRRSELEAA-REEERKAKAISPEECVRRLRAKGQPIRLFGETDKDRRLRLRALELQDQTDFKKAMDLSLVKTDIN-KFKSLLREWGEWLARDD--TTKNTAAGKMAAAQSAQNLKPLFRLLRQRDMPPDVVRALAQMVHYMQ-I-RAYQKANDAYLRMSIGNAAWPIGVTS-VGIHERSALEKIYSDKVGHVLNDELSRKYIQAVKRLMTFNQTVRPPDDNAH Trire2 MNKELSK-TKEKSKKYLKRSEIEAE-RRAAEAERAMPDDELIRKLRELGQPARLFGESHAGRLKRYKKLTTV-QGPIPTTLQ-----------FTMVLTAYEKAMEEKR-----DTSASKMAYSQTRENMKPLFRKFESGDLDDSLLQPIVEIVKALQ-E-RRYVDANDGYLRLSIGKAAWPIGVTM-VGIHERSAREKLHDGEKGHVMGDEATRKYLQSIKRCLTFAQVRWPPQDLRQ Umbra1 LKDEIEK-KRKTLKKYISRAELERL-REKERKKKEVSQEEVQRRLRAKGQPIRLFAETDKQRKARLRTLELMERNDFMRTLDMDWLRTEPE-KLKRMLREWEEALERPE--EVKRSGQGKRAAAQTADYLRPLFKQLKSRAMEPDILARVTEITHHMQ-N-RRYRDAQDSYLQLSIGNSPWPIGVTM-VGIHERSAREKIFAAQVAHVLNDETTRKWIQSLKRLMTFAQTKYPPDSMSQ Ustma22 LKAEIAS-KRKAASKYMRRGDLEKL-REQQRSASPVSNDEAVRRLRAKGEPIRIFGESDKERRLRLRALELIEQNDFRNALQLNLIKTDID-RLKGLLEEWAESLSRPD--QVKHTMQGKLAAAQSADYLKPLFKKLRKRALTPDVLMRIAEIVHYMQ-R-RQYRNANDSYLQLSIGNAPWPIGVTM-VGIHERSGREKIFSSNVAHVLNDEVSRKYIQSLKRLMTFAQTKYPPDDLSM Walse1 LKQELAR-KRKENTKYLKKSQLDSLTPEPITQPQEISNDECIRRLRLKSEPIRLFAESDRERRLRLRALELLAENDLRKALEWKMVKVDND-KMKNMLRLWENTLQRPD--DVRRSKQGQLAAAQTANYLKPLFKALKSKTIQMDVLTLLGEIILYAQ-E-RKYQNANDAYLRLSIGNSPWPIGVTM-VGIHDRSAREKISSGSVAHVLNDEVSRKYIQSVKRVLTFAQSQFPPEDVSQ Zygro1 LKAEIDK-KKN--NRQVEE------------EPRV-AENASNPDESTLERL----------------------PERIERAIE----------QIHDLLKDW--SN--------------EYQPHETAKCFFPLLVRLRKSNLDLDLLTSLATVLYHLQ-R-DEFQQATESYMKLSIGNVAWPIGVTS-VGIHARSAQSRIQGDHNANIMVDDRTRLWITSVKRLITFRESCSV------ [Cluster2130.fasta_al_trimmed; alignment length = 122] Allma1 TKTKSSVQRAIRTKIAEQYPLDDLIPKKSPLD-HIQLLHQYPFMMPALQVDRGAIKFILSSANIMCPGLTSPGAWMSPVAIFAEGKHFPLAIGWLKMSTDDIRKINKGIGVDNLHHLNDLLW Ashgo11 TKVKTSVQRSLKSKLVEQFPIDELLPKKTELD-KIQFVHKYPEAFPTIQIDRGAIKFVLSGANIMCPGLTSSGAALSIVVVNAENKENALAIGKLLMSTEDIKSINKGHGVETIHHLGDCLW Aspfu1 VSPQAAAQKS----------CSAAYAKSSSTD-RATLLHSYPDALPTVQIDRGAIRFVLSGAALMAPGLTSPGGRLQVVAVMAEGKEHACMVGPLKVGTEEMKEKKKGVVMDEGHYLGDGLW Aurde31 TTLKSSAQRAIRAQLLSTFKLEQIWPKKENLE-HMTLLHRYPNILPHVQVDRGAIRYLLAGAHMMCPGFTSAGGSLALVAIHCEGKEHAAGVGVTKLATEEIKKLNKGVGVEVATHLGDDLW Batde5 TQVKSSVQRNFRAKIVEQFPIDDLIPKKDPVD-RVNILHKYPDILPKLQVDRGAIKFVLKAADIMCPGLTSPGGNLTVVAIYAQGKEHAVAVGMTKMATDDMKKINKGIGVSNAHYLNDGLW Botbo1 ALIKSSVGRAVRAQLLAQIPIEQIWPKKEQLE-HISLVHKYPMLLPEVKVDRGAIRFLLAGAHMMCPGFTSAGGSLKAVAIYAEGKEHAAGIGLTKLSTEDIKKINKNVGVETMCFLGDDLW Botci1 SKVKSSVQRAIRTQLVTTYPIDEIIPKKEQLD-RVTLVHRFPTCFPSLRIDRGAIRFVLSGATLMAPGLTSTGGRLEPVVICAEGKEEACAVGLLSMGTKDVKEKGKGPVVEDAHYLGDGLW Caeel TQLKSSVQKGIRKKLIENFPLEEILPKKENFD-HIETLHKYPFILPHQQVDKGAIKFILNGSSIMCPGLTSPGAKLSVVAVMAEGKQHALAIGLMSMSSEEIQSVNKGNGIENLHYLNDGLW Canalb1 SNIKSSVQRGLKSKFVGVYPIDNLIPKKSQVD-KIQTVHKYPECFPRVQVDRGAIKFVLGGANIMCPGLTSPGAKLTIVTVYAEGKENALAIGKLLMSTDEIKSKNKGIGIELLHYLGDGLW Cangl SKVKSSVQRTLKTKLVSQYPIDELIPKKSQID-KIQLVHKYPEAFPTVQVDRGAIKFVLSGANIMCPGLTSAGASLTIVVINAENKENALAIGELMMSTEEIKSINKGHGVELIHHLGDPLW Capow QQVKSSVHRAIRQKAVEQFPLDEVMPKKDPIDSHLQLVHKCPSMITHQTVDIGAFPFVMRGVNVMAPGLTSKGGKLTVVAVMGEGKEHAMAIGIMKMSSDQIKSVNKGIAIESVHFLNDGLW Catan2 TQAKSSVQKSIRAKIVEAYPMDEIIPKKSPLD-RIQLLHKYPFMMPYLQVDRGAIKFILSSAHIMCPGLTSAGAWMTPVAIFAEGKTLPLAIGVLKMSTDEIRKINKNVGVETMHHLNDGLW Cioin NQLKSSVQRQIRNTILEQMPLGDLWHKKENAD-HIELLHKYPFILPKQQVDRGAIKFVLSGANIMCPGLTSPGADLKAVAVHAEGKINSLAIGLMKMSPQKISEVNKGIGIDTIHYLNDGLW CocheC53 SKVKSSAQRGIRSKVLEEYPIEDILPKKEQLD-RVSLVHKYPFAFNRLRIDRGAIRFVLSGATLMAPGLTSPGGRLAVVVIEAEGKETACMVGVLKMGTEEMKKVKKGQACEAGHYLGDGLW Coere1 NPVKASVVRGIRSKLLDQFPIDDILPKKVNFD-RIVLLHRYPDILPAVQVDRGAIKFVLSGANIMCPGLTSPGAKLTIVAVMAEGKENALAIGITKLSTDEIKSVNKGIGVDLLQHLGDPLW Conco1 SQLKSSVQRGLRQKLLDEYPIDELWPKKATVD-HVSVLHKYPGFLPEVQVDRGAIKFVLSGANIMCPGLTSKGAKMKVVAIRAEGKEHAVAIGYTKMSTKDIASINKGIGVDNIHFLNDALW Conpu1 TPPKSSVQRSLRNALLSQWKLEQIWPKKESLD-HLSLLQRYPSILPKVGIDRGAIRFLLGGANMMCPGLNSPGGYLSMVAIFAEGKEHPIAVGITKLESEELRRSKKGVGVEIATYLGDDLW Copci VPVKTSVQRAIRNSILSQWKLEAIWPKKEGLE-HISLLHQYPYILPTVKIDRGAIRFLLAGANMMCPGLTSKGGWLAVVAIHAEGKEHAVGIGVTKLSTEDIKRINKDVGVETIAYLGDDLW Croqu1 TALKSSLQRSIRTKLLSQIPLDVLWPKKETLE-HVSLIHQYPKLLKQVQVDRGATKFVLAGANIMCPGLTSPGAKLTPVAVHVEGKSVACAIGLTQMSGIDMVKINKGIGVDNVHWLGDDLW CryneH991 TSLKSSVQRNIRSSILSQIKLDEFWPKKEALD-RISLLHKYPDMLPHVQIDRGAIKFLLAGANMMAPGLLSAGGKLTIVAIQAEGKQHACGIGKLVASSADIKKAGKGVAVETICWIGDDLW Crypa2 SKLKSSVQRSLRGSLLSTYPIDEVLPKKASLD-RASLVHRFPAAFPTVRIDRGAIRFVLSGATLMAPGLTSKGGRLEPVVITAEGKEHACAVGLLVAGTKEVKEKGKGPVVEEAHFLGDGLW Debha1 SNIKSSAQRGLKTKFVAQFNIDNIIPKKSQAD-KIQVVHKYPQCFPRVQVDRGAIKFVLSGANIMCPGLTSAGAKLTIVTIYAEGKENALAVGKLIMSTDDIKSKNKGIGIELVHYLGDGLW Dekbr2 TNVKSSVQRALRTKLVNQYPIKILMPKKSTVD-KINLIHMYPSCFPRVQVDRGAIKFILSGANIMCPGLTSKGAKLTTVAVYAEGKENALAVGKLLMSTDEIKKVNKGMGIELIHYLADGLW Dicdi NQIKSSLQRNIKNSILAQYPEEDVFPKKVPIN-HINFLHKYPNILPHVQVDKGAIKFVLQGANIMCRGLTSPGAKMAIVAVMAEGKDHASAIGVMKMSTNDIRTINNDIGINNIHYLGDSLY Dmel QQLKSSVQKGIRAKLLEAYPIDLILPKKDSYD-HIELLHKFPYFVTMQQVDKGAIRFVLSGANVMCPGLTSPGACMTVVAIMAEGKEHALAVGLLTLSTQEILAKNKGIGIETYHFLNDGLW Enthi KQVKASQTKHIKQSISTQYPIDELFPKNIPLD-HSTLAMTYPEMMKQVQVDKGAIKHVLSGSNIMAPGLTSAGGKLNYVLIMGEGVQSPLAIGLMKASAVDIKKQNSGVVIDLIQYAGDGIW Falba QLPKSSAVRTIRAAMLKQFPVTEDVPEEAEPH-FYTVLQRFPRLMPGIYVDKGAVRPLMGGSDLMVPGIYKPSLEATVVAVYAIGLQHPFMIGRLTYNVRTILGMQTGNVVENLHTMGDGLW Fomme1 TNVKSSAQRAIRDTLIRDLKLEQIWPKKEVLD-HISLVQKYPSILPRLQVDRGAIRFLLAGANMMCRGFTSPGGELKPVAIFCEGKEHPAAIGFTKLSTEEIKSVNKDVGVELKMYLGDDLW Fusgr1 QKLKSSVQRTLRKDLLDTYPIDEIMPKKATLD-RNTLVHRFPQAFPSIRIDRGAIRFVLSGATLMAPGLTSAGGRLEPVVVIAEGKDEACAVGTLSAGTKEVKAKGKGPVIEDAHYLGDGLW Galma1 TPVKTSVQRQIRAGVLSQWKLEAVWPKKEGLE-HVSFLHKYPYILPKVQVDRGAIRFLLAGAHMMCPGLTSPGGYLRMVAIHAEGKEHAVGVGITKLSSEDMKKINKDVGVETATYLGDDLW Ganpr1 SQVKGSVQRAIRQKIADTYPIDELLPKKAPME-HVNLLHQYPDILPILRADKGAIKFILSGANIMAPGLTSKGATMAPVAVYAEGKEHALAVGLLEMSTDEM-------------------- Gloin1 SLVKSSVQRNIRSKILEQYNIDEVLPKKSSLE-HINLLHKYPHAFPRVQVDKGATKRILSGANIMCPGLTSKGARLTIVGVFAEGKEHALAIGLTKMSTDDIKNINKDIGVENIHYLNDPLW Hisca1 SKVKSSVQRAIKQKLVETYPIDELIPKKASLD-RVTVLHKFPDAVPTIGIDRGAIRFVLSGAALMAPGLTSAGGSLEVVAIKAEGKEEICMVGPLKVGTEEMKKKGKGVVMDEGHYLGDGLW Klula1 SNVKSSIQRNLKAKLLAQYPIDEIIPKKAQIG-KIQFVHKFPEAFPTVQVDRGAIKFVLAGSNIMCPGLTSPGAKLTIVVINAENKETAMAVGKLLMSTEEIKEINKGHGVEMIHHLGDPLW Lacbi2 TPVKTSVQRQIRATVLSQWKLEAIWPKKEGLE-HISILHKYPYVLPVVGIDRGAIRFLLAGAPMMCPGLTSAGGYLTVVAINAEGKEHAVGVGILKLGTEEIKKVNKDVGVETATYLGDDLW Lenti61 VSVKSSVQRSIRAGILSQWKFEQIWPKKESLE-HISLLHKYPFILPMVRVDRGAIRFLLAGAHMMCPGFTSAGGYLVPVAIHAEGKEHAAGIGLTKLGTEEMRKVNKGVGVETVTYLGDDLW Malgl1 SSLKSSVQRSIRTKLMEQYALEKIWPKKESVREHIQLLHQYPVLLPTVQVDRGAIKFLLSGANVMAPGLTSAGGRLTPVAIKAQGKEYEVAIGILQVDTEEIRTQGKGNAIDNIHYLGDDLW Mellp23 TTLKSSSQRTIRLKLSTQMP-NLLCPKKESLD-HVSILHKYPQLLPKVQVDRGAIKFVLAGANIMCPGLTSAGARLVPVAVHAEGKESACAIGFTQMSGEEMKKINKGVGVDNVHWLGDDLW Mnele NQIKNSVQRSIRTKLIDTYPINDILPKKVNLD-HIELLHMYPNMLPKVQVDKGAIKFVLSGAHIMCPGLTSPGADLTPVSVHAEGKINALAIGHMKMSSDDIKSINKGVGIDNVHYLNDGLW Monbr TQLKSSVGRAIQRKLEDQMPLPVLFPKKSPID-RSSLLHQYPNLLPRFQVDRGAIKFVLSGADIMCPGLTSPGAKMTPVAIFAEGKEHALALGETVMSTEDIRKINKDVGVKSISYLDDGLW Morel2 TQVKSSVQRAIRAKILEQYKIDDVMPKKSPLE-HINLLHKYPNMLPRLQVDRGAIKFVMAGANIMCPGLTSKGARMAVVAITAEGKNEILAVGTTKMSTDDIKRINKNIGVETAHYLNDYLW Mucci2 SQLKSSVQRNIRTKLNELYPLEELIPKKTPIE-HITLLHKYPDMLPKLQVDRGAIKFVLSGANIMCPGLTSKGARMAVAAIMAEGKENALAIGLLKMSTQDIKLVNKGIGVDNIHYLTDPLW Mydma TQIKSSVQRGIRAKILEQFPIDAILPKKECME-HIELLHQYPFLLPHEQVDKGAIRFVLSGANIMCPGLTSPGAKMSVVAIMAEGKDHAVSIGLTKMSTQEIAEKNKGIGVDNIHYLNDGLW Neucr2 QKLKSSIQRNLRQSLLTTYPIDDIIPKKASLD-RVSLVHRFPQCFPTIRIDRGAIRFVLSGATLMAPGLTSKGGRLEPVVVLAEGKEEACAVGVLVAGTKEIKEKGKGPVIEEAHFLGDGLW Orpsp11 SQVKSSVQRGIRAKILEQYPIDDVMPKKTPLE-RITLLHKYPDMMPKVQVDRGAIKFILSGANIMCPGLTSPGARMTIVAVFCEGKQHAIAVGVTKLSTDDIRKINKDIGIETIHYLNDGLW Pench1 -------------------------------------------------------------------------------------------------------------------------- Phybl2 SQLKSSVQRSIRTKLSEQYPLDELMPKKTPIE-HITLLHKYPDILPKLQVDRGAIKFVLSGANIMCPGLTSKGARMAVVAVMAEGKEHALAVGLLKMSTEEIRRVNKGIGCDNIHYLTDTLW Picst3 SNIKSSAQRGLKTKFVDQFEIDNIIPKKSQAD-KIQIVHKYPQCFPRVQVDRGAIKFVLSGANIMCPGLTSAGAKLTIVTIYAEGKENALAVGKLVMSTDEIKSKNKGIGIELLHYLGDGLW Plicr1 APLKSSVQRSIRAAVLAQWTLEVIWPKKEGLE-HIAVLHKYPNILPHVQIDRGAIRFLLAGAHMMCPGLTSPGGFLTPVAIHAEGKIHAVGIGITKLGTEEMRKINKGVGVETATYLGDDLW Polpo -------------------------------------------------------------------------------------------------------------------------- Pucgr2 TIIKSSTQRAIRAKLSQQFPLEFLWPKKESLE-HVSLLHQYPMLLPTVQVDRGAIKFVLSGANIMCPGLTSAGARLTPVAVLAQDKSLPCAVGFTQKSAADMRSQNKGVGVDNVHWLGDDLW Punst1 TPVKSSVQRSIRSALLTQWILESIWPKKETLD-HISLLHKYPFLLPKVGIDRGAIRFLLAGAHMMCPGLTSAGGWLTPVAIFAEGKEHPVGIGITKLSTEDIKRVNKDVGVETVTYLGDELW Rhior3 SQLKSSVQRNIRAKLGDEYPLDDLIPKKQPIT-H-------PNILPKLQVDRGAIKFVLSGANIMCPGLTSKGARMAVVAIMAEGKENALAIGQLKMSTEDIKKVNKGIGVDNIHYLTDPLW Rhoto1 APMKSSAQRQIRAKLLEQIPLDLIWPKKETLE-HISILHRFPDMLPRVGVDRGAIKFVLSGANIMCPGMTSATGYLKPVAVHAYGKENALAIGLLAMSTDEIREINKNIGVENITFLGDDLW Rozal11 NQLKASVQRGIRSRLQEDFNLDQILPKKQNLG-QINMLNKDPGMLPKVTVDRGAIKFVLSGANIMCPGLTSKGGSLTVVAVHAEGKEHPLAIGILKLSTDDIKKVNSGIGIDTFCYLNDPLW Sacce1 SKVKSSIQRTLKAKLVKQYPIDELIPKKSQID-KIQLVHKFPEAYPTVQVDRGAIKFVLSGANIMCPGLTSAGADLTIVVINAENKENALAIGELMMGTEEIKSVNKGHSIELIHHLGDPLW Salro -------------------------------------------------------------------------------------------------------------------------- Schco3 TPVKTSVQRQLRSAILSQWKLEAVWPKKEGLE-HISLLHKYPYILPRVQIDRGAIRFLLAGAHMMCPGMTSKGGYLAAVAIYAEGKEHAVGVGITKMSTEEIKKVNKNIGVETTTYLGDDLW Schpo1 TPIKSSIQRGIKAKLVQAYPIDELIPKKSQLD-RLFLVHKCPDAFTQVRVDRGAIKFLLSGANIMIPGLVSKGGNLQYVIVTAEGKEAPAAIGLTKMSAKEMKETNKGIGIENVHYLGDNLW Sorma QKLKSSIQRNLRQSLLTTYPIDDIIPKKASLD-RVSLVHRFPQCFPTIRIDRGAIRFVLSGATLMAPGLTSKGGRLEPVVVVAEGKEEACAVGVLVAGTKEIKEKGKGPVIEEAHFLGDGLW Sphar TQTKSSVARGIRQKVLDSYPIESLFPKKQPLD-RIQLLHKYPDLLPHEQVDKGAIRFVLSGAHIMCPGLTSPGAKMTVVAIMGEGKTHAMAIGRMKMSSEDIQSKNKGIGVDNMHYLQDGLW Spipu1 SKVKSSVQRGIRAAILEQYPIEELMPKKEPLD-RINILHTYPDIMPTVQVDRGAIKFVLSGANIMCPGLTSAGARMSPVAILAEGKEHALAVGKMVMSTSDIKRVNKGVGVDLMHFLNDGLW Sporo1 APMKSSLQRQIRNKILEQYP-------TNALE-HVSVLHKYPGMLPRVGVDRGAIKFVLGGANIMCPGMTSPTGYLTPVAVHAYGKENALAIGLTAMSTDDIRNINKNIGVDMIHFLGDDLW Stehi1 TPPKSSIQRSIRSSILSQWKLEEIWPKKESIE-HVSLFHKYPFILPHVQIDRGAIRFLLAGAHMMCPGMTSAGGGLTPVAFNAEGKEHAVGIGITKMGTEEMKKVNKGVGVESVTYLGDDLW Tapde11 TPVKSSAQRNIKTKVVELYPVDEIIPKKSQLD-RISLVHLYPDAFPSVRVDRGAIKFVLSGANVMAPGMTSAGGMLKVVVIRAEGKEHAVAVGVTKMTAEEMRTKNKGHGVDTAHYLGDWLW Thetr QL-KSSAVRGLKASVVEQYPIDEMVPKKGTPG---TVAMQYPGMMKSVTVDKGTIRAALKGANIMAPGLTSEGGSITPVVIHVEGKSQPIAVGKMELSADTIRAEKTGVAIISVTFLGDGLW Treme1 TSLKSSVQRNIRSQLLVQLPLDEIWPKKESLD-RISLLHRYPALLPHVQIDRGAIKFLLAGANMMAPGFLSPGGLLQLVAIHAEGKEHACGIGKMTSSSEEVRKVGKGIAVEVITWIGDDLW Trire2 QKLKSSVQRSLRNALLATYPIDEILPKKASLD-RNTLVHRFPQAFPSIRIDRGAIRFVLSGATLMAPGLTSKGGRLEPVVIMAEGKEEACAVGTLVMGTKEVKEKGKGPVVEDAHYLGDGLW Umbra1 TQLKSSVQRGIRGKIIEQYPLDDLMPKKTPIE-HLSLLHKYPELLPKIQVDRGAIKFVLSGANIMCPGLTSKGARMAVVSIMAEGKEHALAIGQLKMSTEEIRKINKGIGCDNIHHLNDSLW Ustma22 TALKSSVRRVIRQKLTDQYPLEAAWPNKASVREHVQLLHKFPDMLPSVQVDRGAIKFVLSGANVMSPGLTSAGGKLQCVAIRAQGKDEILAVGVMSMDTEEVRKTGKGIAIENIHYLGDDLW Walse1 TAIKSSVQRAIRQKLLDQFELEQIWPKKESIN-QLQLLHLYPHLLPPVTVDRGAIRFLIAGANVMSPGLTSKGGKLTVVAIFAEGKDHPVAIGICKTSTEEIKKVNKGIGIDTLHFIGDGLY Zygro1 SNVKSSVQRSLKSKLVSQYPIDELIPKKSQVD-KIQLVHKFPDAYPTVQVDRGAIKFVLSGANIMCPGLTSPGASLSVVVINAENKESALAIGKLMMSTEEIKSINKGHGVEMIHHLSDPLW [Cluster2131.fasta_al_trimmed; alignment length = 144] Allma1 MLLVGLD-TRQTQALMRSVNLRARRSYFGKYLK--DMAAMDGMKKNMAMMVPQALIMSFLSFFSGFLLIQLP-FPL--TVRFKSMLQSGIL-TPDLDATWVSSLSMYFISFLG-MNPVFGLILGQGNEKAFMSETEYLIEDRVT Ashgo11 MILVGVT-VTENQYISKAIAMLMRQEYLGKYLALADPNLMGMAKGNLAGYIPQTVIMWWVNFFAGFVLMKLP-FPL--TMRFKEMLQSGVM-TADLDARWVSSISWYFISMFG-LDPVYNLLFGDEA--LMKNYANDLIEDRVL Aspfu1 MILTGIAESKERLSLMRGVNLRMRKNYLGAFLKMTDPAMMGMMKGNMMMMIPQTLIMSWINFFSGFVILKLP-FPL--TIRFKSMLQSGVM-TRDLDVRWVSSLSWYFLNLFG-LQSVFGFILGSDNDKLYQSEAENLIEERVL Aurde31 MVLVGVQ-IREQRAMLRAQILRSISSYLGTFLKMSDPAMMDGMKKQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TNGFKSMLQRGID-TQDMDVRWVSSLSWYILNLFG-LNGVYRLILGGENNKLFQGEKDNLVETRVL Batde5 MVLVGVQ-LRESASLMRARLLRSRKTFLGVYLKMTEPGMMDMMKKNMAMIVPQTLIMSWITFFTGFVLIRLP-FPL--TLRFKTMLQKDIQ-TSDMDVTWVSALSWYFLNLFG-LRSIYTLILGDADAKMFESEKEYLADEILL Botbo1 MILVGIA-IREQRALVRSQALRAISSHLGTYLKLTDPSMMDGMKKQMVMMVPQMVIIGWLNFFSGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDARWVSSLSWYFLNLFG-LNGLFKLILGNDNNKTLLGEKDSLIERRVL Botci1 MILTGIA-IREQRSLLRGINLRPRRDYIGKFLKMTDPAMMGMMKGNMSMMIPQTLIMGWINFFSGFVIIKLP-FPL--TIKFKSMLQAGVA-TRDMDPQWMSSISWYVLCIFG-LQSVFNYLLGSDNDKQFQGEAENLVEQRLL Caeel TFFIGIN-IADGQYLLRARLLRARRQYLTGYLSPMDPSMTEMLKGNMMNMIPMIVVGGWINTFSGFVTTRVP-FPL--TLKFKAMLQRGVD-LVSLDSAWVSSASWYFLCMFG-LRSIYTLVLGSENRAAFKGEWEAL------ Canalb1 MVLVGLN-LRESQFLHRARCFRIRKKYFTEFHAFNDPSLMQMAKGNLMNYIPQTLIMGWVNFFAGFVIMKLP-FPL--TDGFKSMLQNGVM-TPDLNVRYVSAISWYFVNLFG-LKPIYSLLMGSSEEKVFKAEAENIIVDRFL Cangl MVLAGIK-LTENQYVLKAQVLLVRREYMGKYIAFSDPNMMNMAKGNMAQFIPQTVLMWWVNFFAGFVLMKLP-FPL--TIRFKEMLQSGVM-TSDLDVRWVSSISWYFISVLG-LNPVYNLILAEPE--VMKGLANDLIESRIL Capow MFLLGI----DGQGLLRARVLRMRKNFFKGWLMMGDPSMMGMLKNNMSFVIPQMLIMGWINFFSGFIATRVP-FPL--TVRFKMMLQRGIE-LPTLDASWVSSLSWYFLAVFG-VRGLHTLVLGEGNNQVFKAERENLIERALL Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------MLQRGIE-LESLDASWVSSASWYFLNVFG-LRSMYSLILGENNQKAFKAEWEALIEDYVR CocheC53 MVLTGIK-IRQQRSLVRGVNLRARKAYMGKFLAMSDPAMMGMMKGQMTMMIPQTLIMGWINFFSGFVIMKLP-FPL--TPQFKSMLQSGVG-TRDLDVRWVSSLSWYFLTLFG-LQPVYNFILGSNNDKLFLNEAENLIEDRLV Coere1 MVLVGID-IRQGKALMRGQLLAERKRYLGTYLKMTDPKMMDGMKKQMMGIIPQTLIMGWIQFFSGFILIKLP-FPL--GLRFKQMLQSGIM-TPNMDVRWVSSLSWYFINLFG-LRGVFSLLLGGDNNKQFLGMKDTLIEQRVL Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------ Copci M-----A-LREQRALARSQILRTISDSLGTYLKLTDPSMMAGMKTQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLLLGNDNNKLFKAEIDNLVEDRVL Croqu1 MLLVGIA-LREQRILLRANLFRSRREILGSYLNL-DSAMMDGLKKQMVMMVPQTVIMGWINFFFGFVCVKLP-FPL--PNGFKQMLQRGIE-TPDMDISWVSSLSWYFLNLFG-LNSLYRLILGDGNKKLFKAEVENLIEQRVL CryneH991 MLLVGVT-VREQRALGRSALLRALSGSLGEYIKL-EGAAMEGMKKQAVMMVPNMIIMQYINFFSGFILMRLP-FPL--TAGFKSLLSRDIP-MPDLDVRWVSALSWYFLNLFG-LNGVFKLILGAENVKLFKAEVENLVEDRVL Crypa2 MVLTGIA-QREQRSLLRGINVRARRDALGAYLKMTDPNMMGAMKGQMAMIIPNTLIMSWINFFSGYVIMKLP-FPL--TIKFKSMLQAGVA-TKDMDPRWMSSISWYFLCIFG-LQPVFNFILGSDNDKQFLAEAENLVEDRLL Debha1 MVLVGLT-AREKQFLNRAVCFRTRQQYYSDFYAFTDPSMMNMVKGNLMNYIPQTLIMGWVNFFAGFVVMKLP-FPL--TDGFKSMLQSGVA-TPSLNVRYVSSISWYFVNLLG-LKPVYSLLMEDSKDKVFKAEAENIIVDRVL Dekbr2 ------L-LREQQHIRRLANYCAKVRYFTKYLRLTDSSMMQSVKSSLANWVPQSIISWWVNFFKGYVIMRLP-FAV--TSNFKPMLQTSID-TTDLDASYVSSISWYFVNLLG-LKSVYSLIFNDASQQLFQNRIESLTEQRLL Dicdi LFIVSAK-TMQMQTINRVRRLVIRKAYLKGILSFTDPSITDMLKGNIMHLIPQVTMMSWVNFFSGFVACKLPFFPL--TIRFKTFLQRGIE-MGSLDVSYVSSLSWYFLCWFG-SEGINAILLGENMHKIYASEKENIIEDRFL Dmel TFLVGIQ-IQDSQAMIRARLLRMRKNYFTGYFK-NSSALTDMVKGNFINVLPMVVIGGWINMFSGFVTTKVP-FPL--TLRFKPMLQRGVE-LASLDAAWVSSASWYFLNVFG-LRSIYTLVLGENNKAAFKAEWEALIDADML Enthi TVCSNYA-QQEATILQKAQLFCKLRTKFGILMIQMDPTMLGGMKGNMVMMIIQIVLMTWIGMFDGFLVLKMP-FPL--SYRFKLITQQGLG-GMDLDVSYVSSMSWYILIFAG-GRYIIRLFLNDD-VSSFNSAAESIIEDDVM Falba VFLVFLA-VREREALVFTQKFLATRERLGTFLQMTDPAMMSGVQRNMLALVPNSILMLWVNTFRGFVVMRVPLMPP--VFRLKLMLQSGID-VLDLAPAWVSSLSLFFLCLFG-LRGVFDLCLGLAVAKALQKQSEILLESRFL Fomme1 MILVGIA-TREQRALLRSQILRSISSHLGTYLKL-DPNMMGGLKTQAVMMVPQMILMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLILGNDNAKLFKAERDNLVELRVL Fusgr1 MVLTGVT-MREQRSLARGVALRSRRDILGTYLKLSDPGMMGMMKNNMAMIIPNTLIMSWINFFSGYVIMKLP-FPI--TIKFKSMLQAGVQ-TREMDPRWMSSISWYFLCIFG-LQFVYVFLLGSDNHKQFVAEVENLVEERLL Galma1 MILVGIA-VREQRALARSQILRSISQHLGTYLKITDPAMMAGMKTQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLILGDGNNKLFKAEKDNLVENRVL Ganpr1 MVLVGVA-VREMQALQRAARLRLRRTKLGKYLKMTDPQMMDMMKKNMAMFIPQTLIMSWITFFSGFVALKLP-FPL--TLRFKAMLQRGIE-TADMDVSWVSSLSWYFLNLFG-LRGIFTLILGEENSKMFEGEKELLIEERTL Gloin1 MVLVGIA-IRETKALTRGVTLRIRKTFLGDYLKMTDPAMMEGMKKNFAMIIPQTIIMGWINFFSGFVLIKLP-FPL--TLRFKSMLQRGVE-TPDMDVTWVSSLSWYFLNLFG-LRSIFTLLLGEDNHKLFLAESENLIENRLL Hisca1 MVLTGIAESRERLSLLRGVNLRSRKNFLGLFLKMTDPAMMGMMKGNMAMMIPQTLIMGWINFFSGFVLLKLP-FPL--TIRFKSMLQSGVM-TRDLDVRWVSSLSWYFLNLFG-LQPVFGFILGGDNDKLFLAEAENLIEERLL Klula1 MILVGVK-LTEILYIAKARALMMRQEYLGKYLAFTSPGMTSMALGNLVNYIPQTVIMWWVNFFAGFVLMKLP-FPL--TIRFKQMLQSSVR-TDDLDVRWVSSMSWYIISMGG-LTPVYNVLFGGNR--QMKALANDIIEDRVL Lacbi2 MILVGIA-IREQRALARAQILRPISRHLGTYLKLTDPAMMAGMKTQMVMMVPQMIIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLILGNDNNKLFKAEKDNLVEDRVL Lenti61 MILVGIA-IREQRALIRSQILRAISQYLGTYLKLTDPAMMAGMKTQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGVE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLILGGENNKLFKAERDNLVDARIL Malgl1 ----------------------ARKTFLGSYLDFNNEAMMEQAKRSLLMMVPQTMIMGWVNFFTGFVLIRLP-FPL--TQRFKVMLQRDID-TADLDVAWVSSLSWYFLNLYG-LDAIYRLVMGNTRAKLHVAERESLIEARVL Mellp23 MLLVGIA-LREQRILLRANCFRNRRQVLGSYLSL-EAAMMDGMKKQMVMMIPQTVIMGWINFFFGFVCVKLP-FPL--PNGFKQMLQRGIE-TPDMHISWVSSLSWYFLNLFG-LNSLYRLILGDGNKKLFKAEVENLIEDRVL Mnele ------------------------------------------------------------------------------------------------------------------------------------------------ Monbr AYCIGLA-LKEANVLERSARLRARKQYFTGILSMQDPSMTDMMKKQMINMVPMVVIGGLINVFSGFVIIRVP-FPL--TIAFKPMLQRGIE-LTTLSASWVSSMSFYFTCVFG-LSAVYTLALGSNNGQAYKAEWEALVEQDLI Morel2 MVLVGVS-ARETKALQRCGLLRGRKAFLGTYLKMQDPAMMDGMKKNMMNIVPQTVIMGWINFFSGFVLVKLP-FPL--TVRFKGMLQRGVE-THDMDVSWVSSLSWYFLNLFG-LQSVFTLILGSGHHKIFLAEKENLVETRLL Mucci2 MVLVGIA-IRESKALLRGLRLRVRKAYLGKYLKMADPDMMEGMKKQLTNMVPQMVIMGWINFFQGFVVIKLP-FPL--TPRFKQMLQSGVD-TRDMDVTWVSSLSWYFLNLFG-LGSVFSLILGDNNRKMFLAEKENVVEERLL Mydma TFLVGVH-LKQSHILLRSRMLRMRKQFFNGILKMQDPTMMDMMKGNLTNVLPMIVIGGWINTFSGFITTKVP-FPL--TLRFKAMLQRGIE-LTSLDASWVSSVSWYFLNVFG-LRSFYSLILGQDNGKSFEAEWEALVEEDLM Neucr2 MILTGVA-IREQRSLLHGINLRTRRDALGAYLKLSDPSMMGMMKNQMAMIIPNTLIMSWINFFSGYVIMKLP-FPL--TIKFKSMLQAGVM-TKDMDPRWMSSISWYFLCIFG-LQSVFNFLLGSDNDKQFKAEAENLVEERLL Orpsp11 MFLVGID-VKESLAVKYGRLFIMRKNFWGKYLKMLDPATMSGMKKGFANLIPQYVLMSWVSFFAGFVIIKLP-FYL--PLRFKDMLQRGID-TQNLDISWVSSLSWYFLNLFG-LGGIFSLILGRNN----------------- Pench1 MILTGIAESRERLALLRGVNLRMRKNYMGAFLKMTDPAMMGMLKGNMMMMIPQTLIMSWINFFSGFVIVKLP-FPL--TIRFKSMLQSGVM-TRDLDVQWVSSLSWYFLNLMG-LQSVFGFILGSDNDKLYLNEAENLVEERIL Phybl2 MVLVGIA-IRESKALLRGMRLRCRKAYLGKYLKMTDPDMMEGMKKQMMNMVPQMLIMGWINFFQGFVVIKLP-FPL--TPRFKSMLQSGVD-TRDMDVTWVSSLSWYFLNLFG-LGSVFSLILGDNNNKLFLAEKENIVEERLL Picst3 ---------------------------------------MNMAKGNMMNFIPQTIIMAWVNFFAGFVVMKLP-FPL--TDGFKSMLQNGIA-TPDLNVRYVSSISWYFVNLFG-LRPVYSLLMGDSSDKLFKAEAENIIVDRVI Plicr1 MILVGIA-IREQRALLRAQILRSISRDLGKYLKLSDPAMMAGMKTQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFFG-LNGLYRLILGGDNNKLLKAERDNLVENKIL Polpo LFIVSAN-VMEVQTLMRARRLAMRKAYFKE--SFKDQSMTDMLKGNIVNVVPQIGLMTWVNFFSGFVAVKIPFFPL--TIRFKTFLQRGIE-LSSLDVSYVSSLSWYFLCWFG-LEGINSLLLQERPHQLYTSERENIVEQRYL Pucgr2 MLLVGIQ-LREQRALMRSGYFRERRNRLGHYLSL-DPAMMDGMKKQMVMMIPQTVIMGWINFFFGFVCVKLP-FPL--PNGFKQMLQRGIE-TRDMDISWVSSLSWYFLNLFG-LNPLYRLILGDGNKKLYQTEVENLIETRIL Punst1 MILVGIQ-LREQRALTRAQILRAISQSLGQYLKLTDPGMMAGMKTQMVMMGPQMVLMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TQDMDVRFVSSLSWYFLNFFG-LNGLYRLILGGDNNKLFKAEKDNLVEDRVL Rhior3 MVLVGVS-IRESKALLRAMRLRVRKAYLGDYLKMTDPEMMDGLKKQMMNMVPQMIIMGWINFFQGFVVIKLP-FPL--TPRFKSMLQSGVD-TRDMDVTWVSSLSWYFLNLFG-LGSVFSLILGDNNKKLFMAEKENVIEERLL Rhoto1 VILSGVA-VREQRAITRGQLLRALRSSLGSFLKFEDPALQDMMKKQAVGFVPQMATMYLVNFFTGALIARIP-FPL--PLKFGDLLQRGVQLLPSADASWCSTSSWYFLCMFG-IGPVYQLLLGNNSTKIFRAERENLVEERLL Rozal11 VFLIEIESIIQLNALQRCKNLRKIADKMGKYGTLGDPDMTEMMQKNMLTMIPQTLIMGAIHLFSGFVTVKLP-FSL--PLQFKSMLQRGIE-TREMDVKWVSSLSWYFLNIFG-LKS----------PKLLKAELESLL----- Sacce1 MVLTGVK-LTEWQYLQWAQLLIAKKEFLERHLAFNDPSMMNMAKGNMASFIPQTIIMWWVNFFAGFILMQLP-FPL--TAKFKEMLQTGII-CQDLDVRWVSSISWYFISVLG-LNPVYNLILNDQDDKAMHAMANDLVEQRVL Salro TFCVGLV-LMRTQLLQRARLLRARKQYFNGVLTMQDPSMMNMVKGQAINYVPMVVVMSLISAFSGFVIIKVP-FPL--TIAFKPMLQRGIA-LSTLSASWVSSMSFYLTCVFG-LRGLYSLVLGSANGKLYQAEYDALVEKNLL Schco3 MVLVGVN-VRETSAILRGGALRPLARQLGAFLKLSDPAMMSGMKTQMVMMVPQMVIMGWINFFQGFVLINLP-FPLPATSGFKSLLQRGIQ-TPDMDVRWVSSLSWYFLNFFG-LNGLLRLLVGGDDSKAHKAEAENIVETRVL Schpo1 MILIGIE-IREQRLLQRAYALRARKCFLGKYLKLMDDKLMESMKGNMLMVVPQTIIMTWINFFSGFILLKLP-FPL--TLRFKSIFQSGVA-TQDLDVQWVSSISWYFLNLFG-LKSVYALLLGENNSKMMLSEAENVVEKRLL Sorma MILTGVA-IREQRSLLHGINVRTRRDALGTYLKLSDPSMMGMMKNQMAMIIPNTLIMSWINFFSGYVIMKLP-FPL--TIKFKSMLQAGVM-TKDMDPRWMSSISWYFLCIFG-LQSVFNFLLGSDNDKQFKAEAENLVEDRLL Sphar MLAVGID-IIDNGYLQRARMLRMRKSFFKGFFRTQDPNMADMMKGNMSMILPQILLMTWVNFFYGFLTTQVP-FPL--TLKFKEMTQRGVE-LQALDATWISSLSWYFLIVYG-IQGLQILITGSAGNVIFKQEREGLVEGRLL Spipu1 MVLVGVG-MRESAALLRARTLRCRRTYLGSYLKMTDPAMMDMMKKNMAMIVPQTLIMSWITFFSGFVLIKLP-FPL--TLRFKAMLQRGIE-TADMDVTWVSSLSWYFLNLFG-LRSIFTLILGEDNANMFKSEKEFLVEARVL Sporo1 MLASGLA-LREQRALTRGQLLRSIKSHLGTYLKL-DPALIDMVKKQAVGFLPQTILMYYINFFNGFLLTRLP-FPL--TIRFKEMLQRGLIDVPDLDASWCSSISWFFLCSFG-LNPVYRLLLGEENKKLYRDERENLVEDRFL Stehi1 MILVGIA-IREQRALARAQILRSISSSLGSYLKLSDPAMMSGMKTQMVMMVPQMVIMGWINFFQGFVLIKLP-FPL--TLGFKSMLQRGIE-TPDMDVRWVSSLSWYFLNFLG-LNGLYRIILGGDNNKLFKAEKDNLVETRVL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ----------------------RRRQFFGMYNQ-----MSNMMSSQMAMIVPQILTMGIVNFFSGFVILRVP-FPL--TSPFKAMLQQGIQ-LSDLNVAYVSSLSWYFLNLFG-LRGILDIILSDGNPKIFAAEKENLVADRLV Treme1 MVLVGIA-VREQRALARGAILRAFSVSLGGYLKF-DPAMMDGMKNQAVMMVPNMIIMQYISFFSGFILIKLP-FPL--TLGFKSLLSRDIA-MPDLDVRWVSALSWYFLNLFG-LNGVFKLLLGSDNSRLFRAEVENLVENRVL Trire2 MVLTGVA-IREQRALAHGAALRTRRDFLGAYLKMTDPNMMGMMKNNMAMIIPNTLIMSWINFFSGYVIMKLP-FPI--TIKFKSMLQAGVQ-TKDMDPRWMSSISWYFLCIFG-LQFVYVFLLGSDNSKMFKAEAENLIEERLL Umbra1 MLLVGVA-VRESKALMRGSQLRSRKAFLGKYLKMTDPDMMEGMKKQVTNMVPQMLIMGWINFFQGFVVIKLP-FPL--TLRFKSMLQSGVD-TRDMDVTWVSSLSWYFLNLFG-LSSVFTLILGDNN----------------L Ustma22 MILVGVA-LREQRVMARAAALRSRKAFLGKYLQFEPAGMMEPMKKQMVMMIPQTVIMGWINFFSGFVLLKLP-FPL--TVRFKVMLQRDIP-TPDLDVTWVSALSWYFLTLFG-LNAVYRLVLGDDNEKLHHAERDNLIEDRVL Walse1 MILVGLS-IREQRSLMRSAILRKRKQYLGKYLKLSDPDMMDGMKKQMVMFIPQTVIMGWINFFSGFVLIKLP-FPL--TRGFKAMLQRGIM-TPDMPASYVSSISWYFLNLFG-LNSVFKLLLGDGNNKVFKAEIDNLVEIRVL Zygro1 MVLTGIK-LTESQWIYKAQALLLRKEHLGKYLVLSDPNMFSMAKGNLANFIPQTIIMWWVNFFAGFVLMKLP-FPL--TPRFKEMLQSGVM-TADLDVRWVSSISWYFISVLG-LNPVYNLLLSDTE--VMKGLANDLIEQRVL [Cluster2140.fasta_al_trimmed; alignment length = 104] Allma1 SHRKVDVDSLHVANLLARGAALTAALTGDA-PYGTKAVADVLTTARVADAAQYLPPLSPAD-RDLLLKYVYKAMAGALLAWHEKITEVSGVGSIVRVMSDRRVI Ashgo11 DWRRIDIDAFQLRSAGASGDGVQIAVSDP--PYGLLAVLDLLTQVRQADIAGILQQLNRPQ-QDVLLKYLYRGMAGMLLAWFEKLTQQTGINPIVRFLSDRRTV Aspfu1 NYRTINIDVLQVRQLLRGGDALRYVLDTA--PLGMATVVDVLQGIRQGEMTRVLEGVGGSERADCLMKYLYKGMASVLLSWHEKLVELTGTGSIVRVMTDRRTV Aurde31 NFRKIDIDQYAVRSSLSKGDALATVLDGA--PYGLQTLLLILNSTKSTDIPAIVRAMPSES-HDTLMKYIYKGMASVLLSWHEKLTELAGTGCIVRVMTDRRTV Batde5 AHRKTDVD-FDVRNLLSRGNALQTALSNP--PTGTQLVVETLATVRPTDIPAVVKELQPAH-IDVLMKYLYRGMAALLLSWHEKAYEVGGLGSIVRVLSDGRSV Botbo1 NWRRIDIDAYQVRSLISRGDALAAVLTDA--PYGLSAVLLILNSTKSTDIPGIVKGLSQDE-QDTLMKYLYKGMASVLLGWHEKLTEVAGTGCIVRVMTDRRTV Botci1 NWRTINIDALQVRQLLRGGDALRGALENA--PYGLGTVMEVLQSIKASEMTPLLKKIGGGDVLDCLMKYLYKGMESVLLSWHEKVVEVAGLGCVGRCMTDWRKV Caeel SYRKLDVDSFAVQGFLSSNRALHAALLSP--PLKTQLVTKVLQSFKNAEIEATVQKLSIEE-SDILMKYVYKSMEQSLLAWHAQLVAKFGHGAIMRVFSGRQRL Canalb1 DWRSIDIDALQIRSNLSSGQALSLALDNV--PYVSKTVFEVLCSIRNNDLTGFVKSLSSEQ-QDVLVKYLYNNMSGLLLNWFEKTIEVTGVGSIARYLTDRRTV Cangl DWRRIDIDAFQLRSMASSGDAVQLITSDP--PYNLLAVLEALGQVKTMDIANIVGQLNDSQ-VDVLVKYLYKGMSGILLAWLEKITQTNGVKPIVHFISDRRTV Capow AYRKVNVDAYEVKKLLTGGNALKAALADP--PLDVASVLSVLTATKTADIAKIVGNLNPEQ-IDVLMKYVYRGMNGILLAWHAAVFAVGGHGSIIRVITDRRSL Catan2 SHRK------EVSSLLARGDALRRALQGTQ-PYGTKSVVDVLTTARSTDVPTLISQLQPAE-LDLLFKY---------------LTEVAGVGAIVRVMADKRVI Cioin AFRRIDVDQYNVNNLLMGGKALKACLQNP--PVRTLLFVRVISTIKASEISGALQSLSVEE-VDTIMKYIYKGFSGYLLSWHEKVAAKGGMGCIIRVLSDRKRL CocheC53 NWRTINIDALQIRQLLRGGDALQSALENP--PYGLAVVIEILQSIRQSDMSPILSRISGTEALDVLMKYIYKGMASVLLSWHEKLVDIAGPGSIVRVMADRRTV Coere1 AHRKLAIDGLAVRAAITRGNALEKALADP--PYGAQLVSEILMATRAQDIASVVANLVDED-RDVLLKYIYHGLAGVLLSWHERVVENGGLGSIVRVMSDRRIV Conco1 SFRDVNIDIYDVKGLLSKGKALVRSLEDP--AYGAKAVIDSLNSFKISEIPETLKELNYDQ-IDLLMKYIYRGLNGSLLQWHEKIVETNGISSIVRVLTDKRTV Conpu1 SFRKIDIDAYDVRSALARNDALSIALDQA--PYGLQTVVSILNSTRSADIPAVLKDLSVEN-QDTLMKYLYKGMASVLLIWHEKLTEVAGTGCIVRVMTDRRTV Copci NFRKIDIDQFAVRGSLARGDALNTILENA--PYGLQTLLTILNSTKSTEISGVVKALSPDA-QDTLMKYLYKGMGSVLLGWHEKLTEVAGVGCIVRTMTDRRIV Croqu1 AYRKIDIDLYQARSFLTRADVLKLLLTSP--PYGLQTLLDTLASTRTSDIPTVLASLDSDQ-LDWLMKYVYKAMSAVLLNWHEKLTELGGTGSIVRVMTDRRRV CryneH991 AFRKIDIDALEVRGLVSRGDALSTILTDP--PYGTSSLLLILNSTRSADIPTMIKNLDQVQ-QDRLMAYLYKGMASVLLTWHEKLTEAAGVGCIVRVMTDRKTL Crypa2 AWRTIDIDALQVRQLLRGGDALRGCLEMP--VYNLQTVVEVLQSIKASEMTPMLQTIGGSELLDVLMKYLYKGMASVLLSWHEKVVDVAGLGCIGRVMTDWRKV Debha1 NWRRIDIDALQCRSALSLGQALTLALDTP--PYVSETVFEVLCSIKNNDLSNFVKQLDSNQ-QDTLVKYLYKNMSGLLLHWFEKTVEVTGLGPIVRFMADRRTV Dekbr2 DWRSIDVDQYLMRQCTASGDGIKAAVQSP--PYGLQAVLDVLSTSKQSTASSVISKLSQDE-QDVLVKLVFALMDGSLLGWLNKVVEASGEGSLVRYLSDPYKL Dicdi -------MNYEVTKALNAGKALNVALADP--PIYATIVLNLLGSFKDKDVETSVETLNDDQ-LDILMKYVYRGLAPIFFKWHECVLKKGGAGTIIRVISEKKTV Dmel AFRKIDVDQYEITTLLTQGKALLSALQNA--PLRLNITLRVLLSIKSTQMDQAIDTLDQNDLIDVLMKYIYRGFEGHLLQWHEKAFAKGGVGCIVRVLSDTNRA Enthi -------------------------------------------------------------------------------------------------------- Falba KHRNIDVDSLNVRTLLNKGDSVAVAVDNP--PFNLETVMSSLSAVRAADIPAVIKSLTPEQ-VDNLVKYIYAGFAHLLL-WHEKAIEVGGLGSITRVLTSRKTV Fomme1 AFRKIDIDAYTVRSALARGDALNIVLEGA--PYGLQTLLSILGSTKATEIPGILKSLPQDS-QDTLMKYLYKGMASVLLGWHEKLTEIAGAGCIVRVMTDRRTV Fusgr1 AWRTINIDALQIRQLLRGGDALRGSLETP--VYNLHTIIEVLQSIKASDMSPLLKNIGGSELLDVLMKYIYKGMASVLLSWHEKVVEVAGLGCIGRTMTDWRRV Galma1 AFRKIDIDIYMVRGMLSKNDALTVILDNA--PYGLQSLLTILNTTKAAEIPGVLKALSPDT-QDTLMKYLYKGMASVLLGWHEKLTEVAGVGCIVRTMTDRRRV Ganpr1 SYRKLDVDNVDVRGLITRGNAIALAVEEPL-PYGISAVIEPLTATKTADIPNVVKQLNPEL-LDRLMKFVYRGMAAALLNWHAAIVEVGGVGTIARVLTDRKIL Gloin1 SFRSIDVDALEVRNLLTRGDALIKAIENP--PYGTQIVMEVLNSTKA--TVEFVKSLATEQ-QDIL-------------------------------------- Hisca1 NYRTVDVDSIQVRQMLRSGDVMRYVLDTA--PLGLATVVEVLAGIRQGEMTRVLEGVGGAERGDCLMKYLYKGMASVLLSWHEKLVDIVGVGSIVRVMTDRRTV Klula1 DWRRIDIDAYQLRSYTSSGDAVELFTTDP--PYNFSGILEVLTQVRQVDIANIVKRLDRKQ-QDALIKYLYKGMSGILLAWFEKLTQVAGVNPIVHYLSDRRTV Lacbi2 AFRKIDIDAYAVRSSLAKSDALSVILDNA--PYGLQTLLTILNTTKATEITGVIKSLSQDS-QDTLMKYLYKGMASVLLGWHEKLTEVAGVGCIVRTMTDRRTV Lenti61 NFRKIDIDQYAVRSSLSRNDALTLVLENA--PYGLQTLVSILNSTKATDIPGIVKALSTDA-QDTLMKYLYKGMASVLLGWHEKLTEVAGTGCIVRAMTDRRLV Malgl1 DFRHLDVDQYDVRARISSGDALHAALADP--PTGLALVMDILNSTRTTDIMPALKALNMDE-RDTLMKYLYRGMEAVILSWHEKLTQVAGTGCIMRVMTDRRIV Mellp23 AYRKIDIDLYQARSLLARADVLQLLLTSP--PYGLSTIIETLSTTRTSDIPSILSNLNSDQ-LDWLMKYIYKSMSAVLLNWHEKLTELSGTGSIVRVMTDRRRA Mnele EFRTVDVDAYEVKKLLNLTKALKLALQNP--PIGYETVLSVLKAFRTPEIEAAVGDLSDGD-VDVLMKYLYKGFSAALLLWHEKVVKRGGVGCVIRVMVDRKGI Monbr -------------------------------------------------------------------------------------------------------- Morel2 AFRKIDIDALEVRSLLQRGNALSTSLQNP--PYGTQTVMEVLNSIKVADVPQLVKSLSPEE-QDVLMKYLYAGMAGHLLAWHEKLTEVAGQGCIVRVITDRRTV Mucci2 SWRRIDIDQYDVRNLLTKGDALIRALEEP--PYGTKTVTEVLNLFRASDIAQVIKSLSHEQ-QDILMKYLYAGMGSVLLTWHEKLTEVAGNGCIVRVMTDKRTV Mydma NFRAVDIDELEIQNLLNVKKALKLLLEQP--PF-FQLMVRVLSQTKSTEIDSIVQQLSQTQ-VDTLLKYIYKGFNGVLLNWHEKVFAATGLGGIMRVMTSRTSV Neucr2 AWRTINIDALQVRQLLRGGDALRGCLEMP--VYALHTVIEVLQSIKASEMTPMLQRIGGSECLDVLMKYLYKGMGSVLLSWHEKVVEVAGLGCIGRVMTDFRRV Orpsp11 -------------------------------------------------------------------------------------------------------- Pench1 NYRTINVDALQVRQMLRGGDALRTVLDTA--PLGLATVIDVLQGIRQGEMTRILEGVGGAERADCLMKYLYKGMSSVLLSWHERLVEIAGTGSIVRVMTDRRTV Phybl2 SWRKIDIDQFDIRNLLTRGDALTLALSDP--PYGTQAVLDVLTQFRATDITPVINSISQDE-QDVLMKYLFAGMASVLLTWHEKLTEVAGTGSIVRVMTDKRTI Picst3 DWRRIDIDAYQVRSALSSGQALQLALDHA--PYISETIFEILCSIKNNDLSSFVKKLDSSQ-QDTLVKYLYKTMDALLLSWFEKTVEVTGLGPIVRFMSDRRTV Plicr1 AFRKIDIDAYAVRSSLAKGDALTLTLENA--PYGLQTLVTILNSTKSSEISATIKALSQDS-QDTLMKYLYKGMGSVLLGWHEKLTEAAGTGCIVRAMTDRRTV Polpo ------MSNYEVTKFLNQSKALPVVLADP--PIYAAIVINVLSNIKEKEIDGCLESLDADQ-LDILMKYIYRGLAALFFKWYEATLKKAGMGCVVRAISERKTV Pucgr2 AYRKIDVDAYQARSFLTRGDALKLLLTSP--PYGLSSVIETLSSTRTSEIASIVQSFDQSE-QDWLMKYLYKGMSAVLLNWHEKLTEVAGTGCIVRVMTDRRRV Punst1 NFRKIDIDQFTVRGSLSKGDALTTVLENA--PYGLQTLLTILNSTKSAEIANIVKSLDQDK-HDTLMKYLYKGMASVLLGWHEKLTEVAGIGCIVRVMTDRRTV Rhior3 SWRKIDIDQYDVRNLLSKGDALACALQDP--PYGTKMVTEVLNMFRAADIADIVKSLNPEQ-QD--------------------LTEVAGNGCIVRVMTDKRTV Rhoto1 NFRRIDIDQYTVRGLLQRGDALKEVLREGEWPYGLATVLSILNSTRSTDIPTLVQQLDPSE-QVTLMKYLYKAMENVVLGWHEKLTEVAGIGCIVRVMSDRRRV Rozal11 -------------------------------------------------------------------------------------------------------- Sacce1 DWRRIDIDAFQLRSLATSGDAVQLLTTDP--PYSFKSVLEALTQVRQADIGNVIKNLSDSQ-RDVLVKYLYKGMSGVLLAWLERITQVSGVTPIVHYISDRRTV Salro GFRRTDIDKFEAIGLLNGGKALKAALKSP--PLSLKVVLDILGAFKSTEVAAAVKELSQDE-CDLLMKFVYRGMENILLTWHKQATEHGGLGCVVRAMADRKTV Schco3 NFRKIDIDAYAVRSALSKNDALTIALENA--PYGLNTILSILNATRSNEISGVVRALPQDA-QDTLMKYLYKGMSNVLLGWHEKLTEAAGTGCIVRTMTDRRTV Schpo1 TFRTLDVDSIQARSAIQTGNGLKTLLSYV--PYGLNAFVDVLSNIRAADIPAFVKECSTEE-IDNIVNFIYRGLASVLLNWHEKVVEISGIGCIVRVLNSRPDL Sorma AWRTINIDALQVRQLLRGGDALRGCLEMP--VYNLHTVIEVLQSIKASEMTPMLQRIGGSECLDVLMKYLYKGMASVLLSWHEKVVEVAGLGCIGRVMTDFRRV Sphar --------------MVSSGKALKEAAGAP--MYRVIAVGEVFASFKSANIKQAVEDLSEEE-RDVALKYVFRCMEATVLGFHKAIVEAGGEGAIVRVMMDRQRV Spipu1 SHRKINVDQYEVRNYLSRGDAVAKALENP--PAGTATVMEALAAARSTDIINIVKGLSTQQ-MDILMKYIYRGMGAILLTWHEKATEVGGLGGIVRALTDRKTV Sporo1 PFRKINIDQYTVRQLLQSGQALHECLREGEWPYGLSAVVSVLNSSRSTDIPNLVSTLSPSE-QVTLMKYLYKAMENAVLGWHEKLTEVAGIGCIVRVMTDRRRV Stehi1 AFRKIDIDAFAVRSLLSKGDALVTILENA--PYGLQTLVTILNSTKSTDIPNVVKSLPPDT-QDTLMKYLYKGMASVLLGWHEKLTEVAGVGCIVRTMTDRRMV Tapde11 -------------------------------------------------------------------------------------------------------- Thetr DFRNLDVETMEINSMLSRGDALAAAMDQP--PTDGLLVASILGGVRDSEIETAVNSFSPDE-QDLLMKFVYRGMAGKLLKWHAALFKACGHGAIVRALSDRASV Treme1 AFRKIDIDALEARGLVSRGDALKEILADP--PYGTQALLLILNSTRATDIPGILKNLKQDQ-QDRLMAYLYKGMASVLLTWHEKLTEVAGVGCIVRVMTDRRTL Trire2 AWRTVNIDILQVRQLLRGGDALRSCLETP--VYNLQTIIEVLQSIKASDMTPLLRGIGGSELLDVLMKYIYKGMASVLLSWHEKLVEVAGLGCIGRTMTDWRRV Umbra1 AFRRIDIDQYDVRNLLTRGNALTKSLEDP--PYGIKTVVDVLNQFRANDIPTAIKGLNLDQ-QDVLMKYLYAALSGMILNWHEKLTEVAGPGSIVRVMTDKRTV Ustma22 NFRKIDIDQYEVRTLIGRGDALSLVLSDY--PYGLQSLLEIVNSTKSSDISNAVKSISIDQ-RDALMKYLYKGLEAVLLGWHERLTEVAGTGCIVRVLSDRRRV Walse1 NFRKIDIDAIQVRGLVNGGDALGLILDDP--PYGTDTVIQILSSTRTSDISNVINNLQPNQ-QDNLMKYIYKCMSNVFLSWHEKLTQVAGTGSIVRVMTDRKHI Zygro1 DWRRIDIDAFQLKSFATSGDALQLATSDP--PYGFRAVLETLTQVRQADIANVVKQLQPQQ-QDVLIKYLYRGMSGILLAWFEKLTQVAGVQPVMHYLTDRRTV [Cluster2141.fasta_al_trimmed; alignment length = 143] Allma1 RGVLALSGGAAAFLQGLTTNNMYTGFLTAQGRVLYDALI-AFLIDADRHLRRYLLRSKLALVT-DEYRVFMFRL--------------------------------------------------------------------- Ashgo11 KAFISVRGDAVKFLNGLITAKLYSAFLNSKGKVLTDTVVPEYLLQCDALLQRHKLLQRVKIRDD--LSVWRARLRRG-VLEVLPLEVNFDLYEDAVSFDKGCYVGQELTARTHATGVLRKRCAPVIVKKQPI-GKLLVKLIYI Aspfu1 RGLISITGDSTTFLQGLITQNMYTAFLNSQGRVLNDAFIPAWLVEVDKHLKKHKLRSKLKLLEDGERTVWVRRMLHG-IAEALPLECNMDM-MRGVDFRKGCYVGQELTIRTHHTGVVRKRIVPVQLKGRSA-GKFLCRLEIM Aurde31 RRVLSVTGDAARFLNGIISASMYTAFIHAQGRVLYDAFVDGYLVEYD-LLKRFVLRSKVKLMD-DELAVWLHRILNG-VPEAFPMESNLDV-MGAVDFRKGCYVGQELTVRTYHTGVIRKRILPVQLRPRST-GKLLLRLEHL Batde5 RMVLRLEGDAAIFLQGLVTNHILAAFLNAQGRVLMDAFIPSFLVECADHLQRYKLRKQVKIIS-DSVDVWARRICLG-IPESLPLESNLEL-IQGVDFQKGCYLGQELTIRTYHTGFTRKRIVPVQLSKGVV-GKYLVRLESV Botbo1 RTVLALTGETRSFLNGIISTAIYSAFLSPQGRVFYGVFFNGFLVEYD-LLKRFILRAKVRVVG-EEWDVWLHRILSG-VPEAFPMDSNLDM-MGGVDFRKGCYVGQELTVRTYHTGVIRKRIMPVRLRPRGT-GKLLMRLEHV Botci1 RRLISLRGDSMKYLQGVITNDIYSAFLNAKGRVLNDVWIENWLIEVDAHIKRYRMRAKFEVVGEEEMGIY--------VEE-------------GVEMKEG-------------TGYM---------------GKE------- Caeel RVLLKLHGDTNAFLQGLIT---AAFLLNTKGRIVEDVLLDDLFLECSKEILKYRLRKQVEISSDQ-----NLRRSAG-IAELLPFQANGDL-LNMVSLDKGCYVGQELTARTAHTGVIRRRILPFECKKNKV-GKIILQLSSF Canalb1 KSIIKIRGDATKFLNGLVTSRLNSMILNSKGRVVTDCFLPGYLLEVDTILKLHKLSAKVDIDKK--LYSYQRRFQNG-LFELLPFECNLDY-TNGLSLDKGCYVGQELTIRTFNNGVIRKRIFPVQFRKTSL-GKIMLAVSDV Cangl KSYLQVRGDTIGFLNGLVTSKLYSAFLNGKGKLVTDSIIPEYLLEFDKSFESHKLHNKIKFVKNT--KTWQCKLQYG-FLDLMPLELNFDYFPNTVSNNKGCYVGQELTARTYSTGILRKRLIPIEFRKKAA-GTLLFRIEHF Capow RRILRISGEAADVVQNLTANDI-TAMLNHLGRVLADAFVTEFLLDVDQALQPFVRLADVDLAEWQLVQVFDRRYALG-LAESFPLESNFER-LNGVHFNKGCYLGQELTHRSHSRGVTRKRILPFVTSSKSI-GVVLLRLDSV Catan2 RQLLLLSGDSTSFLQGLITNHMYSSMLTPQGRLLFDSFVPEYLVDVHGHLRRYKLRSKVTIVDVGEWRVWLHRLVHG-IAESLPLEMNMDY-LNGVDFRKGCYVGQELTIRTYHTGVVRKRIVPVIIAGKPV-GKWLMRLEHV Cioin RAVVQLGGDTIEHLQGLVTNDVYAMMLNTQGRIDHNLILGEVLIDCDELLKRYKLRKKVEILERNDLNIWIWRYKVG-VPESLPLESNLDF-MHGINFHKGCYLGQELTARTHHTGVVRKRLIPVEINNKSA-GRLLIKLDYE CocheC53 RRLIALSGDTAKFLQGLITNNVYSAFLDARGRILWDVFVWACYVEVDGHLKRHKLRSKIQIISQEAVRVWLQRYRNG-IPEALPMECNIDL-SQGIDFKKGCYVGQELTIRTKHTGIVRKRILPVELKGRAT-GKFMCRLENM Coere1 RGLIEVSGDATEFLQGMQCNHILTGFLTPQGRMMADAFVPVYLIEVDAMLDFYKLRAQVRIAT-SQYAVWLRRILKG-VAEAVALETNLDY-MQGVHFGKGCYVGQELTIRTHHRGVVRKRVVPVLFRRVPP-GKVLMRLEQV Conco1 QAYLKLEGDQISFLQGMTTNHIYTGILSPQGRVLFDTFLDSLILETHKHLLKYRLLSQVDIAT-DNFSTLLERYRLG-IPEALPMESNMEL-MNGVHFSKGCYIGQELTTRTKHRGVIRKRIVPI------------------ Conpu1 RAVLSVSGQASEFLNGILATHVYAALLHAQGRVIHDVFITEYLIEYD-LLKRYVLRAKVRVVS-SEWDVWLHRILHG-VPEAFPMESNMDI-MGGLDFRKGCYIGQELTVRTYHTGVVRKRILPVVLRPRGH-GTLLLRLEHV Copci RALISVSGDANTFLNGILSTHV-SAFLHAQGRVLYDVFIPSYLIEYSPYLKRHVLRSKVKVAS-GNYDIWLHRILHG-VPEAFPMDSNLDM-MGGVDFRKGCYVGQELTVRTYHKGVIRKRIHPVILRPRGT-GKLLLRLEHV Croqu1 RALISISGDSTGFLQGLTTNHIYTAFLSPKGRLLFDCFLPAFLLDHDSWLSRFVLRSHVKLFRKDT-QLWLHQLLNASLPPTLPFEANLDH-HRAIDFRKGCYVGQELTARTYHTGVIRKRLVPISIKKKPV-GKLLLRIDHL CryneH991 KSVLELSGDAQKFLKGLSCKDVYSGFLNASGRVLHTAFV-SYLITHESHFPPFKLRSKVRIVT-NQWDAWLHRMLLG-VPEALPLESCMDI-HGGVDFRKGCYLGQELTVRTYHTGATRKRILPVRLKPRSA-GKILVRLEMA Crypa2 RRLLSISGDAPKFLQGVITQNIYGAFLTATGRVLYDVFIESFLVEVDAHIKRYKLRAKFTVLDRQEATVWVRRYLLG-VPEALPLEGNLDV-MGGIDFRKGCYVGQELTIRTKHRGVVRKRVLPVVVKGRSA-GKWLCRLEIM Debha1 RSLLQIKGDATKFLNGLSTSRFNSMFLSSKGRVVTDCFLPTYLIEIDSLLKLHKLSAKVSIIKS--MHSYRRRFMNG-LFELLPFEMNLDL-TNGLSLEKGCYVGQELTIRTYNNGIIRKRIVPIQFRTASS-GKLLANLSDI Dekbr2 -SMVIISGDATKFLNGLLTIRLYGMLLSSKGRVDSDLFVPSYLVEFNSLLKLHKLRTCISIPPK--LQSWLLRIKQG-LVEPLPFEFNIDY-ANGINYNKGCYIGQELTSRTWTRGVIRKRIMPANF---------------- Dicdi RSLIKVVGDALKHLQGLTTNNLYNGFLQGNGRLLFDSIIDSFIVDIDSHLKQYKLRNKIDIVT-ENFNVYLFRLSQG-IPQIIPLEYNFDL-LNGVDFHKGCYLGQELTSRTHFTGLIRKRIFPVVMVSRST-DKFMLKVENI Dmel RELIRVHGEVVPFLQGLATNDVYAHFLNKAGRLLYDTILETILVECDRHLRTYRVRRRIEVVD-DEYTPWLLRYKQG-VGECFPLEANADY-LHGVSFHKGCYVGQELTARVHHSGVIRKRYMPIRLAGAKL-GRVLLRIEKV Enthi ----------------------------------------------------------------------------------------------------------------------------------------------- Falba AVLRLSADDLLGFLQGVTAQD-YTAFLSNVGRVLSDAFVDVLLLDVPAHLRKMAFRKRITILS-GSVVVAALQKSLG-LPDIFPLEANLDM-AGGINVRKGCYLGQEQTARTVFRGAVAKRLVPLELAGSAA-GTTLVPFDLA Fomme1 RALLYLSGQATEFLNGVVSSTVFSALLHAQGRVLYDIFVDGYFIEYD-TLKRFILRSKVRVVS-SEYDVWLHRILHD-VPEAFPMESNLDV-MGGLDFRKGCYVGQELTVRTYHTGVLRKRILPVHIRVRGT-GKLLLRMEQV Fusgr1 RRLISVTGDSAKFLQGIITANVYGAFLTATGRVLYDVFVPAYLIEVDAHIKRYKLRAKLTVLGEDEASVWIRRYING-IAEALPQETNMDI-MNGIDFHKGCYVGQELTIRTRHRGVVRKRILPCVIRGRSA-GKWLCRLENM Galma1 RSVLSITGQSTEFLNGLLSSSV-SSFLHAQGRVLYDIFLNGHFLEFD-YLKRHVLRSKVKVVT-EEYDVWLHRILHG-VPEAFPMDSNLDV-MGGLDFRKGCYVGQELTVRTYHTGVIRKRIIPVTIRPRGS-GKLLLRLEHI Ganpr1 RSLFLIQGDSLKFLQGLTTNDVYAGILTATVRLLYDVFL--VLLECHSNLRKHILRSRVKIVS-TEFSVWLRRIFLG-VPETLPLEINLDV-MGGVDFNKGCYVGQELTIRTHHKGVVRKRVLPVELVERSV-GKLLVRLEL- Gloin1 ---------------------MYTASLNPVGRVLFDAFIPTFLVECDSHMKKYLLRSKVNIVS-SLYQIWIRRILHG-VPEALPLQSNFDY-MGGIDFRKGCYIGQELTFRTYHTGITRKRILPVQLKGRPV-GSILLKLDII Hisca1 ----------------------------------------------------------------------LRRILHG-VPEALPMECNMDI-MGGIDFHKGCYTGQELTIRTHHRGVVRKRILPVQLKGRSA-GKFLCRLEMM Klula1 KSYIRLLGDSIKFLNGLVTSKLYTGFLNMKGKLLTDSIIPEYLMEFDSTLDNHKLLSKVKFVQNEELRTWKERFKFG-LFDLLALEANFDYFEDSINSDKGCYVGQELTARTFATGVLKKRCVGITIRTRPA-GQLVVRKDYI Lacbi2 RGIISVFGQAFSFLNGLLSSSI-SAVLNAQGRVLYDVFLPGYFLEYD-YLKRHILRSKVQVVS-EDYTLWLHRIIHG-VPEAFPMDSNLDA-MGGLDFRKGCYVGQELTVRTYHTGIIRKRTFPVLLRPRGT-GKLLLRLEHV Lenti61 RAVISVTGQAAEFLNGLTAASVYSAFLQAQGRVLHDIFIQGYLVEYD-MLKRHILRSKVKVVT-EEYDVWLHRILHG-VPEAFPMDSNMDI-MGGLDFRKGCYVGQELTVRTYHTGQLRKRTLPVIIRPRGT-GTLLLRLEQV Malgl1 ---------------------------------MADAFLPSILVEVDKFVKRFKLRSKFQIVS-DAWDVMIHRMLQG-VPESLPLESCIDY-MHGVDFRKGCYIGQELTARTFFTGLVRKRIMPISLRSRSA-GKFLLRLEQV Mellp23 KHLISISGDSKTFLKGLITNHIYTAILNPKGRLLFDCFISSYLIEVCDWLSRFILRNKVKLLSKQF-SIWLHQLLNASLPYTLPFEANLDH-HHAIDFKKGCYVGQELTARTYHTGVIRKRLVPLSISQRPI-GKLLLRIDHS Mnele ----------------------------------------------------------------------------------------------------------------------------------------------- Monbr RAVLAVRGEALTFLQGLTTQDLHTMFLHAKGRILCDALARGFYFEVDAHLRSFKLRTKVSF---------YLRLALG-LSESLPLEANIEH-WNGVSFKKGCYLGQELTARTHYSGMLRKRLLPMRIAGKPA-GTVLVRTAHL Morel2 RGLLQIHGDASKFLQGLITNHMLAAFLSPKGRVMYDVFIPAYLIECDAHIARFVLRSKVKMVT-ESFDVYVRRIVNG-VPESLPLECNLDY-MNGVDFRKGCYIGQELTIRTYHKGITRKRIMPVQYPVRAS-GKTLVKLDHV Mucci2 RSLLELEGETAKFLQGLMTNHMYAAFLTPPGRMLYDTFIPKFIIDCPSHLKRYILRAKVKVCS-EEYKLWIRRMLQG-LPESLPLESNFDY-MNGVDFRKGCYVGQELTIRTFHTGVVRKRIVPIQLSKRGV-GKFLMRLEHI Mydma NGVISVHGDCKKLLQGMITNDVYSMVLNVQGRILYDLFLHGYLMECNSYLNRYKLRSKVFFR--DDLNVYNLRYQLG-ISEGIPLEHNLAL-LNGVSFTKGCYIGQELVARAHHTGVVRKRVVPLLL------GKLLLRLKEI Neucr2 RRLISVSGDASKFLQGVITNNIYTGFLTAQGRVVHDVIIQSFLIEVDAHIKRYKLRSKFNLLDPEERALYLRRFLLG-IPEALPLESNMDV-MNGIDFRKGCYVGQELTIRTKHRGVVRKRILPCILKSRSAPGKWLCRLEVM Orpsp11 ---------------------------------------PEYLIDVDKYLKRYILRSDIHLAS-KNLKVWIHRILNG-IPESFPFEANLDF-LNGVDYHKGCYIGQELTYRTHKRGTTRKRLIPVQF---------------- Pench1 RGLISITGDSTTFLQGLITQNMYTAFLNSQGRVLNDAFI--WLVEIDKHLKKHKLRAKLKLLEEGERTIWVRRILHG-VAEALPLQCNMDM-ARGIDFRKGCYVGQELTIRTHHRGVTRKRLLPVQLRNRSA-GTFLCRLEVM Phybl2 RGLLELRGDTVKFLQGLTTNNTYTSFLTPQGRMLYDAFIEKWIIECDEHLKRYQLRAKVKMVT-QEYSAWIRRLLNG-VAEALPLESNMDY-MHGVDFNKGCYVGQELTIRTHHTGVVRKRMMPVQISKRSV-GKLLMRLEHV Picst3 KGIIQVVGDATKFLNGLITSRMNSMFLNSKGRVTADCFLPNFLIEVDSLLRIHKLSAKVKIVSD--IYLYMRRNVNG-LFELLPFECNLDY-TNGLSLDKGCYVGQELTIRTYNNGVIRKRIMPVQFRKASS-GKILVTLSEI Plicr1 RAVLSVSGQASDFLNGILACT-FSAFLQAQGRVLYDVFLRSYLIEHD-ILKRYVLRKKVKVLS-DEYNVWLHRILHG-VPEAFPMESNLDV-MGGLDFRKGCYVGQELTVRTYHTGVIRKRILPVVLRPRGS-GRLLLRYSAL Polpo RSILKVSGDAVKLVQGLTTNNMYTGFLSSTGRLLFDAVVQQLFIDVDSHLHYYKIRNKATIVT-EEFALFLYRVQNG-IPQVIPLEYNFDL-LNGVDFHKGCYLGQELTSRTHYTGLIRKRLFPVVMPSRTT-EKVIVKVDHI Pucgr2 RGLISLKGKSKTFLQGLITNNLYTAFLTPPGRLQFDGFVQCLLIDHHLWLRRFVLNSRVKI-SKDSRELWLHVLLHASLPPTLPFEANLDY-HHGVDFRKGCYVGQELTARTYHTGVIRKRMVPVSIKQKTI-GKLLLRIDHD Punst1 RAILSLTGQASEFLNGQLASSV-SAFLHAQGRVMYDVFIPSYLIEYD-MLKRYVLRSKVKIVT-EEYDVWLHRVLHG-VPEALPMDSNLDV-MGGLDFRKGCYVGQELTVRTYHTGMVRKRVLPVCIRPRGT-GKLLLRLEHV Rhior3 ---------------------MYTAFLTPQGRMMFDSFIPKFIIDIPSHLRRYMLRSKVKLVS-EEYNLW--------------IGKDFKK-LE-IDFRKGCYIGQELTIRTYHTGVIRKRIVPVQISKRGV-GKMLMRLEHV Rhoto1 RAVLAVSGDSQKFLQGLVSNDVYANILKADGRYMHDLMLPAYLIEHDSYFKRHKLRSKVKLAE-EDLVVALHRLTHA-VPEALPLEANIDL-MNGVDYRKGCYVGQELTARTHHKGVVRKRGMVFRLRARPS-GKLSVRTDQV Rozal11 VDVLSSQG--------------YTTCLNAKGRILTDCFMNHVLLEIPGHFKKYCVKVSVHFVS-DLFKVYKRRIKLG-IMD-------YDY----VDFAKGCYLGQESVTRIEHQGVVRSRTMSTQI------GVLVLKCDHT Sacce1 RTYIRIRGDTVKFLNGLVTSKLYSAFLNGKGKLITDTIIPEYLLELHGVLQTHKLANKIKFIDHSSLKTWEIRFQKG-LIDLLPLELNFDFFPNTISTNKGCYVGQELTARTYATGILRKRLVPVKLKQRPA-GLLLLRTEHF Salro RSVLQVDGDGAEFLQGMLTNDVFSMLLNPKGRVLVDAFVERFYLDLPRYFTRFRLRSQVEFVS-DTVDSVQLRISMG-FGESLPLQCNLDY-LHGVSWTKGCYIGQELTARTHHMGMTRKRLMPITLTGKAV-GDVMIRLEPA Schco3 RALLAVTGQAVEFLNGLVASEVYTAFLHPQGRVLHDAFVKGYVIEYD-LLKRYILRSKVKLVT-NEYDVWLHRILHG-VPEAFPMESNLDI-MGGLNFRKGCYVGQELTVRTYHTGVVRKRILPVALRPRGT-GKLLLRLEQV Schpo1 KSLIRVEGDAVKFLQGLTTNKIYTGFLNTQGRVLFDSFIDELYVEIDKHLKKYNLRSRCSIIPSEELSIKVFRYRNG-IPESFPLESNMDW-MKGIDFHKGCYLGQELTVRTYYTGVTRKRIFPFIISRRSP-GKILVRLQYL Sorma RRLISVSGDASKFLQGVITNNIYTGFLTAQGRVVHDVIIRSFLIEVDAHIKRYKLRSKFNLLDPEERALYLRRFLLG-IPEALPLESNMDV-MNGIDFRKGCYVGQELTIRTKHRGVVRKRILPCILKSRSAPGKWLCRLEVM Sphar RSLIKVHGDSVKLLQNLTTNDVSSAILNNLGRVLFDVIINEFYVECEQHFKKYKLRSKVKFEDGLEVTAFRCRYHVG-VPEAFPLESNFDV-LNGIDFDKGCYIGQELTARAKFVGVTRKRLLPVTIKGKSV-GKFLLRL-SV Spipu1 RGFLQLDGDAAKFLQGLVTNQIFCAFLSAQGRILYDAFIPCYIIEHDAHLKRYKLRAKLSIES-ARYRAYVRRILYG-IPESLPLESNLDL-LSGVDFRKGCYLGQELTIRTYHTGVTRKRIVPVQFAAGGV-GKVLMRLENV Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 RAVISVSGQASEFLNGLLTTSVYSAFLQAQGRVIYDVFVPAYLLEYSPMLKRHVLRSKVRIVT-QEHDLWLHRIIHG-VPEAFPMDSNMDF-MGGVDFRKGCYLGQELTVRTYHTGVIRKRILPVILRPRGT-GKLLLRLEHV Tapde11 RSLISIKGDTFKYLQALTTNNL-TSFLNAQGRVLYDAFI---LVEVDAHLGRYKLRSKFEMLDPSELGIYRHRYRHG-VPEALPMESNIDY-MNGLDFHKGCYLGQELTVRTYHTGVIRKRIVPVTVKARPA-GRVLLRLDKV Thetr RKVVEVFDDAEEFLQGVATVDV-SAILSSKGRMLFDLFVSRFALDVASVLARYKLRAKV--AEADELGVYAHRVALG-LPEALAPEMSLDA-LSALSLTKGCYVGQELIARTHARGAIRKRILPLALSSKAV-GRVLLRLRNV Treme1 ISVLEISGDATKFLKGLSCKDVYSGFLNASGRVLHTTFIPTYLITHQSLLPPFKLRSRVRFVS-SEWDVFLNRTLLG-VPEALPLESCMDI-HGGIDFRKGCYLGQELTVRTYHTGATRKRILPIRLKARSA-GKILVRIEMA Trire2 RQLLSVTGDAAKFLQGIITANVYTAFLNATGRVLHDVFIDGFLVEVDAYIKRYKLRAKVAFIDPAEMSVWIRRYLHG-VPEALPLESNMEH-MNGIDFHKGCYVGQELTIRTKHRGVVRKRILPCAIRGRSA-GKWLCRLEIM Umbra1 RSLIEIEGDTSKFLQGLITNHMYTAFLSPQGRLLYDTFIPKFIIECAGHLKRYILRSKVKLVT-SEYSIFIRRILHG-IPESLPLESNFDY-MNGVDFRKGCYIGQELTIRTYHTGVVRKRIVPVQIKKRAV-GKFLMRLEAA Ustma22 RGVVQVSGDTVKLLQGLVSNDVYAGFMNPQGRMLADVFIPRWLLDIDSFIKKFKLRSKVKLLS-TDYHVVLHRITNG-VAESLPLENNLDY-MHGVDFRKGCYVGQELTARTHHTGVVRKRIVPLSFRGKAA-GKFCLRLEQV Walse1 RSVLNLTGDSIKFLNGICTQTIYAAFLTPQGRMLYDTFINSYYLEVDNLCKKYQLRSKVRL---HKMDNARDRYKLG-IPESLPLECNLDY-MNGVNFRKGCYVGQELTIRTHHTGVVRKRVLPMKLKPKQA-GKLLFRLEML Zygro1 KSFLKIRGEAPKFLNGLVTSKLYTGILNSKGRLLTDTLLPEYLLEFDPMLDLHVLTSKVK-LYEGGFTSWRLRFEQG-YVDLLPLELNFDFLPNAVSADKGCYIGQELTARTFATGILRKRLVPVTLRQRPA-GSLMLRIEHF [Cluster2142.fasta_al_trimmed; alignment length = 251] Allma1 QHGRKKPTLSHALK---VLEQKKIAEYRAKATQCLELR-HRHLTA-DALAATAALLNDNTEYYTIWNYRRELLAAV-AALQQELVWLMLPCNPKSYWIWNHRRWTLETLEMKLVDRFLDLDPRNFHAWDYRRYVVA---VEAEFQFTSTKVAQNFSNFSAWHQRSKLFAE--WAFPDALNELDLLHNAV--YTEPNDQSAWLYHKWLLVRRAELAVIEELGALVFLCTL---VAELKQIDPY-RAQYYATL Ashgo11 MHGVKRRLTQEALKQKRAQDKQRIKAYRDQTARVLRLR-DAGYSM-EALAETTSLLQMNGEFNAVWNYRRDIIAAL-GFWEAELK-LTLRESPKVYWIWNHRQWCLQHHELALVGKMLELDPRNFHGWHYRRVVVRASLDSAELSFTTEKINENISNFSAWYQRAQLIPR--M--SRFAEEASYIINAM--YTDAEDQSVWMYLKWFAMLTKFRENIMALKMLVFLGSIAPTLERLIELDSM-RRNRYIHM Aspfu1 GHGIPRYSSEEALQ----QELRKIQNYQALDRLVRDKI-AGHYTP-ETLQKISELLSSNPEYYTVWNYRRRVLQHEFALIKKDLQ-FLLRKFPKCYWIWNYRMWLLDEAELALVGKMLSLDSRNFHGWGYRRFVVE-SMAQDEFEYAKKMIGTNLSNFSAWHYRTKLIQR--LTRKKMLDELDLIHRAL---CDPYDQSLWFYHQNLMYLRKEIGEIQEYQALIDCTLLARKLSELKKLDPL-RCGRWLDF Aurde31 -HNVKRARSAEVVAARKKKEEAQLAEYLALEKDVLERR-RANYSE-EAFNLTTKLLKLNFEYYTVWNYRRHIL----DILSAELS-FTLRQHPKVYWIWNHRRWCLQRVELFVVEKMLDADARNFHAWNYRRYVLA-----DEIAYTQRKIEANFSNFSAWHQRAKVYAA--IRTSKD--EFELVKNAL--FIDPNDQSGWLYHRWLIVLQRELDVIAELDSLVHYKRLLLRLAKLETIDPI-RRQRYQDL Batde5 -------------------------------------R-AHSLDN-ESLQVTTTLLTQNPEFYTIWNFRRDILVHM-TDCEIELR-LTLQGAPKSYWVWNHRRWTLQHMELKLLDYMLDLDARNFHGWDYRRYVVA-RKPQQEFEYTLNKINQNFSNYSAWHYRSKLFPW--ISCNTAISDLEIVRNAV--FTEPADQSAWLYQRWLL------------------------------------------- Botbo1 MHGVKRTRSPEAIQARKQRERAKIDEHRALAAQVLSLK-AANWGA-DALALTTRLLATNPEFYTVWNYRRYILLRGVTLLNDDLA-MTLRQHPKVYWIWNHRRWCLENIELYVVEKMLDADPRNFLAWDYRRYVLA-----TELDYTTRKIESNFSNFSAWHQRSKVLAS--LAVKDA--EFEFIKQAM--YVDPYDQSAWLYHRWLVVLEREIAVIEELDSLVHYKRLLIKLSELERIDTF-RGQRYRDL Botci1 ------------------------------------------------------------------------------------------------------------------------------------------MVESEFAYTTRMINAELKNFSAWHNRSKLIPR--LERRQFLDEFDLITKAMWNDAYPYDQSVWFYHQFLMYIKQQIINLRDFDALFEYTLAVCELSELRKLDPM-RAGRWDGL Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 QHGIKRVKSEEAKRLKLEKDQIKIKNYRQLTDEIFELR-ANEYSD-EALIKTNELLIINPEFYTIWNYRREILINNYDILNQDLN-FVLKKFPKCYWIWNHRRWLLFELEFGVVSKLLDLDQRNFHGWHYRRFVVELKINLDEFNYTTLKIQKDFSNFSAWHNRTKLIPK--INPILLLKDLEMIKTGV--YMSPEDTSVWLYLYWLLILHEQLQLINELKSMIFINALIQNLKQLAKIDPL-RKNKYLDQ Cangl ---------MELLKQKRVQDQLKIEKYRQLTDTVLGLK-DKRFTI-ESLKLTTNLLELNPEFNAVWNYRRDIIVDL-KFWEDELM-FVLKRFPKVYWIWNHRLWTLQNYELVIVNKLLDADARNYHGWHYRRIVVSNDMNKEELEYATTMIKSNISNFSAWHQRVQLIQK--M--TLFIEEIDFVTNAM--FTDAEDQAVWFYIKWFIMLKTFWENITMLKLLLVIQQIQKSLEKLLTVDPL-RKNRYKHL Capow MHGRSRVKAAEVEEAKQKERSKKLALFQQLNARVFAKY-QAKYDD-EAFALTRELLSRSPEIYTLWNYRRCIMLKR-DECKAELT-FLIATNPKCYWLWNHRRWLLEQAELDLTSQFLNRDSRNFHCWDYRRHVA--VSLKSEFEFTTAKIEQNFSNYSAWHYRSKLLPM--IDSSTILEEFDMVQSAC--FTEPEDQSAWFYYRWLLVLESELGAFREILTSLLLM-----LDRLRAVDPC-RRRYYNDL Catan2 QHGRSKADAATALQAKYLVEQNKIAQYRAKVTECLGLK-AGNFSD-AALSLTASVLADNPEFYTIWNYRRTIFEARIELLMSDIKWLLLPLNPKSYWIWNHRRWCLEVLELALVNKFLDMDARNFHAWGYRQYTTS---TTAEFDYTTAKISSSLGNYSAWHARSTLLPA--YSLESLLDELDLLHNAM--FTEPDGQSHWLYHKWLVKVREEIELLQEIGALAFLY-----VVRLQEMDPD-RSGYYATL Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SHGIARGTSEEARQ----KELEQIAQYKELADSVNTKI-AEKYTL-EALGLVTKLLNENPEYYTIWNHRRRVLM-ALDLLQDDLQ-LTLRKFPKCYWIWNHRNWLLRQGELQLINKMLHADSRNFHAWGYRRIVVSKSLAESEFEYTTKMIKTNLSNFSAWHNRSQLIPK--IARRAFLDELSLICEAI--NTDPFDQSIWFYHQYLLYYENEIEYIREYEALLGLAEAYLELGELKRLDPL-RRGRWDDL Coere1 MHGKRRVAAKEPTQDEKEEARQQLEQYCALNSRVMDLK-AQSFTA-DALDATRQLLELNTELHTVWNYRRTII----KMLEQELE-FLIRNNIKSYWMWNHRMWALSLLELSLVDKLIGMDARNYHAWDYRRFVIA-AVDEQEFAFTTAQINRDCANHSAWHNRSKLLPA--IRREEVLQENELIQNAI--YTDPEDQNAWLYYDWLLLLHNKIAAIRELVELV--------LRTLKGVDSY-HAGRYADM Conco1 LHGKKREKPQEVIDAKLAQDKIKIKNYTELCQEVYQLK-NDQYNE-RGLELTKEIIILNSDFNTIWNFRRQVLLE-LNYLEEELR-LVILIYPKSYWLWNHRRWVLETSELMLVSKMLSLDNRNFHGWNYRRHILD---LNDEIKYTKTKIEQSFSNGSAWFYRTKLIEKKIL-------EYDLVKNAT--YTDPEDQSAWIYYRWLIRISKELEELQEIEKLNNYIALL--YNHLKKIDQY-RKNRYIEL Conpu1 MHGVRRSKTPQAIATRKEQEKAEIKSYLALSDEVLGKK-KLNWSK-DAFELTQRVLRRNPEFYTVWNYRRQIMLNGLFLLSEELK-FTLRTNPKVYWIWNHRRWCLANIELALAEKMLEADARNFHAWSYRRYILA-----TELAYTKKKIQSSMSNFSAWHQRSKTYTA--LKFEPE--EFDLVHSAL--WTDPADQSAWIYHRWLIILEAEISLIEEMESLVHYKRLLLRLQRLQTIDPP-RKQRYRDI Copci MHGIKRVKTPEALEARKQKERAKIQEFTALSEDLLRRK-KESYSE-DAFKLTTRLLHINPEFYTIWNYRRNILLKGLRILTDELG-MTLKSHPKVYWIWNHRRWCLENIELYVVEKLLDADARNFHAWDYRRYVLA-----SELGYTSRKIGANFSNFSAWHQRSKVLPR--LTSRES--EFELVRNAM--YTEPADQSVWVYHRWLVLLLREIEAINEMESTVHYSRLFIKLKELEVLDPY-RAQRYRDL Croqu1 MHGVKRSKTREPGE---AEEKQRLEEYQVLNKSLLERN-AAQFEQTDSLSLSAALLTLNPEHVTAWAFRRRCLMAISEKLKLEMQ-LTFERHPKAYSIWEHRKWVLNQMELSLVHRLLKVDGRNFHVWDYRRYLISTDRLKSELAFTTKQIESNFSNFSAWHYRSKVLEP--LERESRLKELEWVRNAL--WIDPNDQSGWLYHRWLMIRQTEIQSIKELATLLQYC-----LDKLLELDPL-RKQRYVDV CryneH991 MHGIKRSRTPQAAEAKRLKEQSKIEVYLALEKDVLTRK-SAKYSE-EALGKTTQLLDLNPEFYTIWNYRRDILLY-LGHLTTDLR-LTLLVHPKVYWIWNHRKWCLESVELKLVEKMLDADPRNFHAWGYRRYVLS-----EELKYTQSKIESNFSNFSAWHYRTKTLAA--IDIKKVKDEFELVTQAL--WTDPGDQSGWLYHSWLV-----------INALAQYTLLLAKYEVLIEVDAD-RKERYRDM Crypa2 -----------------------------------------------------------------------------------------MEFPKCYWIWKYRSWLLQQAELGLDTKMLTKDRRNFHAWGYRRNVVGKSMVESEFDFTTKMIHVDLSNFSAWHNRSKLIPR--LARRKFFDELALIREAL--NVGPDDQSLWYYHQFLMYITREIEDIKDYERLMDYTLALAALSKVRELDPM-KKGRWDDL Debha1 QHGIKREKTEVAKKAKAERDKTKIENYRNLTIDILQEK-DNKYTK-DTLNKTTTVLLLNPEFYTVWNYRREILLDLF--LEDDLK-IVLKRLPKCYWVWNHRIWCLNQLELAIVSKLLEMDSRNFHGWQYRRFLVELKINIKEFEYTTSKINKNISNFSAWHNRTKLIPK--ISPYSIMVDLELIKTGM--YMDPEDTSVWLYLYWLIILHEQLKLIEELKSIISIKGLIKRINKLIEIDPL-RKGRYLDQ Dekbr2 LHGTKRFKTDEKSRIRRNKEAARIANYRKLQDTVFTGY-EKNYNN-ETFKFTTKLLNWNPELYTVWNYRRDILINSKNFLEQELR-FVLKSFPKCYWIWNHRKWCLKEDEMNLINMFFQVDERNFHAWGYRMFIADMNVYQKEFVFTTRMIKRNISNYSAWHRRSVLVDL--LDKAEFLREYEVFLNAI--YTDPDNSSVWIYGKWLFFLDQAYGAVNEIKFNLYLLKFKFVKKKLIKIDNM-RKQRYLDF Dicdi MHGVLKVRSEEKAKAQRLKELEKIESYNKLVKSFEELREKQNYDE-ISLSVSKLVLIENPEFYTIWNYRRLAILQ--VIYQNEMK-FLIQRFTKSYWIWFHRQWIALRMEMKLCTKLLNFDLRNFHCWGHRRFILK----EDELKYTTEKVEQNFSNYSAWHQRSSILPK--IEPEQLLEEFELVRNAV--YTEPKDSSSWIYHKWLVVLKNELTQIYDIYTTLLLK-----ISQLIKLDPD-HKNYYKSL Dmel MHGRVKVRTEEERERKKKEQALKVRAYRAAMGRIQKKR-EAGLDN-EMLSLTVQILLRNPDVSMLWNIRRECVLEKLSIFTCELD-LTLMVNPKSYNAWHHRCWTLEQNEVKLCNKYLKFDERNFHTWDYRRYVTG---ATQELDFCTEKIRANFSNYSSWHHRSLLLPE--LMSEEKLQELEMVLTAA--FTDPNDSSAWFYQRWLLELQTQLQSCLDLTSALLMRAIDFSLAKLEKVDFL-REGYYKDL Enthi IHGITKAEQIEAAK----ETQNRIKIFNELKEKYRNKTGSLE----EQLKLNSELLTISSQDYQYWNERKEMIEELLKILSYELE-LTLPKNSKSYVIWYHRKWSISKMERELCAKMIGKDSRNFHCWGYYLWVLE---QEEDLKFITDSINNNFSNYSAWHHRSVIFSSY--QLEKVIEEFTLLLNAF--YIEPNDQSAWIYYRWLLILKEQFNKIKELFTMVELYQITKKIKTLQRVDSM-RSGYYKEL Falba MHGVRRERTAAAAKIKREATEKKIANYQEVAVAFFDLR-KAQVEPETSLRVTYDLLDLNPELNTAWNYRRDAFCRLFELIEQELR-GIIRAFPKSYWVWHHRVWVICCLEQHLCKEMLRLDDRNFHCWDYRRFVVSAEVYQAEFDFTRSKLADNFSNYSAFHLRTRLLPA--L-------EFELVNNAN--FTEPNDQSPWFYLRWLLILREQLDNLEQFFALVAQKLVLFSLTELEQMDSL-RAGYYHDL Fomme1 MHGVKRTRSAEALEARRLKEHSKLEAYLKLDDDVLAKK-KAKWTL-DALNLTTRLLTTNPELYTVWNYRRDIFTNGVDILITDLE-LVLRQYPKVYWIWNHRRWCLEHIELRAVEKMLDVDARNFHAWAYRRYVLA-----AELAYTKQKIEANFSNFSAWHQRSKVFTS--MKSKEE--EFELVKQAL--YVDPYDQSSWIYHRWLILLQREIGVIEELEMLVHYKKLRLELSKLEKIDSY-RAKRYQEI Fusgr1 SHGIARTATEEQRK----QDLVKIEKYRNLEDQIREKI-SDNYGP-ETFQFTSKLLRLNPEYYTIWNARRRCLISGLEVIRAELA-FTLMEFPKCYWIWNYRLWILDRAELGLVSKMLAKDRRNFHAWGYRRHVVAQSLVEPEFLYTTKKIHDDLSNFSAWHNRSQLITR--LSRKAFLDELDLVDEGL--NVGPEDESLWYYHQFLVYLEREMTNIKDYEALAEYAMTLAQLSHLRKLDPK-RNGRWHDL Galma1 RHGVKYTRTAEERDARRRRELSKIEEFTKLKQTTLAKK-KAKWSR-DAFELTTRLLQVNPEFYTVWNYRRSILVNGLNLLMDDLA-MTLKAHPKVYWIWNHRRWCLENIELFVVEKMLDADPRNFLAWDYRRYVLA-----TELTYTSRKIEANFSNFSAWHQRSKTLAS--LKSREEGKEFELLRNAM--YTDPNDQSVWMYHRWLVLLEREIAAIQEMECIAHYKRLLLTLDRLREIDPA-RRRRYQDL Ganpr1 KKEQKEV-DPKILEAKKEREQKRIEEYRQLLRDVRHKR-AAQRDD-AALALTRSILTINPEAYDVWNFRRVILIEQ-TRCKAELR-LLLKVFPKSYWLWNHRQWVLQTLDLALVAAMLNLDARNFHGWDYRRYLIA-STPKTEFDYTTKKIDQNFSNYSAWHYRSTVLNK--AGLEEQLEDFELVRSAI--YTEPADQSAWLYQRWLLILLREIESLRELLTLVYLL-----LDRKREI-------FYQDL Gloin1 MHGRKRVKSAEVEKLRKEKEVTKIKEYRNLVESYFQKK-DKKFDN-DALALTTKILSQNPDFYSIWNFRRLILLNGLQTLSTELV-FLFQLNPKSYWIFNHRRWCLETMELQLVGKFLELDARNFHAWDYRRYVTS---TQIEFDFTTTKINQNFSNYSAWHQRSKLLPL--LEKKKLIDEFELVKAAF--YTDPDDQSAWLYHWWLVLLQREINVVRELQTLANLL-----CDRLIKIDKF-RTKRYE-- Hisca1 --------TEAAWQ----KESQKIQTYNELVSIVNSQR-AEHFST-EALNKTSELLTKNPEYYTIWNTRRLILQHQFNIIKADLQ-FLLRGYPKCYWIWNHRLWDLEQTELALVGKLLSLDSRNFHGWGYRRQVVSASMAKAELDYTTKMIGANLSNFSAWHNRTQLILR--LERKKMLDELKLIHRAL---IDPYDQSLWFYHQNLMYLENEVEAITKYQALISCGVVICRLCELKRLDPL-RQGRWLDL Klula1 MHGVTRRETKELLRKKREKERQEILDYRELSDEVLELK-NKRANK-DSLLKTTQLLNINPEFNTIWNYRREIIKLL-TFWDGELA-FTLKVRPKVYWIWNHRVWCLEHYELAIVGKLLEMDARNFHGWHYRRYIVSNCLNSQEFEYTTAKINQNISNFSAWFQRTNIIEH--M--ESFIDEFQYIKNAM--FTDAEDQSVWTYLIWFIMLKELTEIIELLKTLLVIEFIQKDLDKLIIIDPL-RKNRYLYQ Lacbi2 -HGVKRIRTVQDREAKRQREQSKIKDYLSLTNVILSRK-KNKWSE-DAFNLTTRILQLNPEFYTTWNYRRNIFAYINKILSEDLS-MTLKAHPKVYWIWNHRRWCLENIELFVVEKMLDSDPRNFHAWDYRRYILA-----TELAYTSRKIESNFSNFSAWHQRSKVLSS--LNNIWC--EFELIRNAM--YTDPNDQSVWMYHRWLVIAHHLIASVREMESIVCYKRMLIKLQQLQELDPL-RRRRYEDL Lenti61 MHGVKRVRSREALAAQKERELAKLKEFQGLTAEVLDRK-KRKHGR-ESFDLTTRLLHVNPEFYTIWNYRRLILLDGVEILSDDLS-LTLKQHPKVYWIWNHRQWCLRQVELFVVEKMLEVDPRNFHAWNYRRHVLD-----SELAYTKRKIEANFSNFSAWHQRSKVLTS--LKSIEE--ELDLVKNAM--YTDPGDQSVWIYHRWLIVVDREILSIDEMESLVFYKRLLLRLAKLQRVDPD-RKQRYIDL Malgl1 -----------------------------------------------------------------------------------MG-------------WNYRRWVVEELAMSKVDGILDPETRTMH-----------ALAYQELKYTLAKIESDFSNFSAWHSRSKLLPR------------------------------------------------------------------ERLDSCARSKQRISG Mellp23 MHGVQRPKPRHPSE---EEERLRLEEYQLLNKSLLERN-HRKYEEDDSFNLSTALLTLNPEHVTAWSFRRKCLISIIEKLNDEMK-FTFENHPKSYSIWEHRKWILKQMELNLVERLLKKDGRNFHVWGYRRFLISEERFKSELNFTTKQIESNFSNFSAWHYRSRLLES--KEKEIRLKEFEWVRNAL--WIDPNDQSGWLYHRWLMVREAEIGSIKELSTLLQYC-----LKKLVELDPL-RKERYLDV Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr MHGRVKVRTEEQEALKELERQKKCKGYLVLRNALFAKR-NAQHDR-DGLQLSEQILLLNPDFTTVFAYRRETLLALL---------FTLKRNPKSYNCWHHRRWILNQEELELCTLFLKHDERNFHCWDYRRFVVE---VATELAYTEDKISHNYSNYSAWHNRSNLLLQ--FLATEALDELELLTNAF--YIDPQDQSAWYYHRWLL------------------RA----------------------- Morel2 RHGRKKEQSPEVLKAREEKEAVLVREYLALKDTLKEIV-ESNRDN-DALKVTTALLRKSPDYYTIWNVRRTILKEGFKIYTGELE-FVLKLNPKSYWMWNHRRWCLESMELAMVGKFLEMDARNFHGWDYRRYIIRLDRAQSEFDFTTSKIHKNFSNYSAWHNRSTLLGK--LEREAIVDEFDLVKNAI--YTDPEDQSAWLYELWLI-----------------IL--------------------YKA- Mucci2 -HGRKREKTEEVVKARKAKEAVKIKEYNQLVDECREKM-KNKYNQ-DTFKLTSQLVEWNLDYYTIWNYRRILLQEFVKVYNKELM-LFIKKNPKSYWMWNHRIWCLQHMELGLVDKMLTMDARNFHGWDYRRFVVG---VQQEYKFTTQKINQSFSNYSAWHQRSKLLPE--IEKNQVALELDLVKNAI--YTDPEDQSAWLYYWWLL-----------LQTLVHFL-----LDKLCDIDSD-RRLRYK-- Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 NHGIARTSTEEQRQ----KDLERIKDYRALEDQVRHHA-AKNYSS-DVFALTSKLLRLNPEYYTVWNVRRRCLISGLQILQKELH-FTLLESPKCYWIWSYRLWILKQVELGLTSKMLLRDQRNFHAWGYRRHVVEKSLVESEFEFTTKKISQNLSNFSAWHSRSKLIPR--LARKAFFEELNKIGEAI--NVGPDDQSLWYYHQFLMYLRREIESIQEYEALFDYTLYLCQLGNLKKLDPM-RSGRWADL Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLTLVKIL-----LEKLKDIDVF-RKEYYLDF Pench1 ---VPL--ADDC------------------DSMV-----AEHYTI-ETLKKISELLSSNPEYYTAWNYRRQVLQYQFELIMNDLH-FLLRSFPKCYWIWNYRLWLLDEAELALVGKMLTLDSRNFHGWGYRRFVVE-SMTQKEFEYAKKMIGANLSNFSAWHYRTKLIQS--LDRRRMLDELSLIHQAF---IDPYDQSLWFYHQNLMYIRNEIEEIQEYQALIECTLLASKLSELKKLDPL-RRERWLDF Phybl2 VHGVKRVRTEDVIKARREREAGKITEYNALVRQCHEKL-EAKFSP-EALTVTTQILYTNPDYYTIWNIRRLILINGITIYMNELG-LFIRINPKSYWLWNHRRWCLETMELKLVVKMLTMDARNFHGWDYRRYVVR---VRQEYEFTTQKINQSFSNYSAWHQRSKLLPE--IEKNTVARELELVKAAF--YTDPDDQSAWLYYWWLVILKEEIEAVRELQTLAHFL-----FNKLSELDTY-RRCRYEES Picst3 QHGIKRVSSAEAKRLKLEKDKSKIAHYKQLTENIFSLR-NLQYTV-ESLKETTQILQINPEFYTMWNYRREIFEHL--LMDNDLK-MLLKRFPKVYWIWNHRRWCLFELEYAVVSKLLELDSRNYHGWQYRRFVVQLGINIEEFKYTTSKINKNFSNFSAWHNRSTLIPK--ILPRSILTELELIKTGM--YMDSEDTSIWLYMWWLLVLEEQLANVEELKTIILVKGLIQQIQALIEIDPL-RKGKYLDQ Plicr1 MHGGKRVRSKEAIDARRQREASKLKEYLALTDDVLARK-KRRWSR-DAFEQTLQLLHINPEFYTVWNYRRNILLNGITLLSNELS-MTLKAHPKVYWIWNHRRWCLENVELFIVQKMLDADARNFLAWDYRRYVLA-----SELAYTRRKIDANFSNFSAWHQRSKVFSS--MKSREQ--EFELVTNAM--YTDPNDQSVWMYHRWLIILDREIGLIQDMESLVYYKRLLSKLKELETLDPD-RKRRYQEI Polpo MHGVLKVKSEEKARELKAKEKIKIDEYRSLVNAYTEHR-KLNFND-NSLLVTKKVLEINPEYYTVWNFRRDTINH--TLYTSEMK-FIIQRYTKSYWVWYHRKWISQRIELKLCSKLLDLDLRNVHCWGYRRFVGE----KKEFDYTTVKIEQNFSNYSAWHQRSALLPK--MEPTELFDEFELVRNAA--FTEPKDQSTWIYHKWLVVLEGEIVAINEIYTLLTLK-----LNNLKSIDSD-HIKYYESL Pucgr2 -----------------------------------------------------MVLRINPEHVTAWSFRRHCLLTLRSALRDELP-LTFQRNPKAYPIWEHRKWVLGQMELALLEKLFKLDGRNFHAWDYRRYVISD---ADELAFSGQQIEANFSNFSAWHYRSKLLQS--REKEEILAELEWVRGAL--WIDPNDQSAWLFHRWLLIQAAEYASIAEIAALIRAR-----LDRLIALDPL-RRQRYLDL Punst1 SHGVKRARSPEAVAARKQKEQAKLNEYISLTDTIFSKK-KSEWSQ-DAFQLTTRLLQLNPEFYTIWNYRRNIMTKGLDLLSTDLQ-MTLKQHPKVYWIWNHRRWCLENVELFVVEKMLDVDARNFHAWGYRRYVLA-----TELDYTTRKIEASFSNFSAWHQRTKVLQT--LQSREE--EFELVHNAL--YTDPADQSAWLYHRWLIVVEREMSVIQEMETLVHYKRISIRLKRLIELDPA-RRRRYEEI Rhior3 --------------------------------------------------------------------------------------------------------------------MLSMDARNFHGWNYRQYVVG---VESEYQFTTKMICKSFSNYSAWHQRSKLLPE--VEKNEVARELDLVKNAI--YTEPDDQSAWLYYRWILLLIEEINTVRD---------------------TA-RKHRYEDQ Rhoto1 MHGVRRSRSAEVERKKREKEQKRVDEYRSLLQAVQQKA-ASKYTQ-EALDLTTRLLSFNPELQTGWGIRRRILLNGLRILEGDLQ-LTLQQNPKVYCLWEHRKWVLETMEIKMVEMYLEKDARNFHSWDYRRYLVS-----SELAFTTRKISANFSNFSAWHYRTKLLTK--LKERLE--EFELVKQAI--WSDPNDQSAWLYHRWLLLVRREIEGIDELDSLVHYKRLLVRLGKLKEVDPM-RRARYQDL Rozal11 ------------------------------------------MSEDNLLRWTERGLLLNADLYSLWNLRKRNFLK--ILLENDLN-LTIQSFPKSYCVWFHRKWILNN-ELALTEIIIDDEKRNF----------------------------NFSNYSAWHHRSNMILN--MEKREAITDIEFIKNAI--FTEPNDQSAWFYYKWLIQIKAQIYPIFTKEKRISFESMASDLSELHKLEPT-AKCKETKI Sacce1 MHGIKRKQTKELLRQKRVQDEKKIYDYRSLTENVLNMR-DEKYSI-EALKKTSELLEKNPEFNAIWNYRRDIIASL-PFWDKELV-FVLKDYPKVYWIWNHRLWVLKHYELAVVNKLLEQDARNYHGWHYRRIVVGKSLDKEEFEYTTIKINNNISNYSAWHQRVQIISR--M--KEYIREISYIINAM--FTDAEDQSVWFYIKWFIMLKDLRENILLLKILLVLEDILEELVQLIDADPL-RKNRYLHL Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MHGVKRVVTPEALEAKKKREQARLQEYLALSEAVLSKK-RARISK-EAFDLTTKMLEINPEFYSVWNYRRDIMTKGLDLLSADLA-LTLRAHPKVYWIWNHRRWCLANVELYIAERMLEVDARNFHAWNYRRYVSA-----NEIDYTMQKIKSNFSNFSAWHHRSKVLPT--LASRET--EFDLVRNAM--YTDPNDQSVWMYHRWLVVLEREISAIQEMDSLVHYKRLLLRLEDLQQKDPA-RRQRYRDI Schpo1 MHGILRVKSEEQRKLKAEKERAKIEEYRGLVSRFQEAR-KRKYSE-GNLKLTTELLDWNPETYSVWNYRREILLNDVDLLDNELK-YVMKVFPKVYWIFNHRRWCLENAEMMITEKLLSADARNFHGWHYRRYVVS-SLAKKEMEYTTSAIATNFSNFSALHNRTKLIET--ILAKQILEELDMIHQAV--FTDPDDSSVWIYHRWLMYLQKEIELIQECESLVNYEALC--VDKMIKVDPQ-RRGRYRTL Sorma NHGIARTSTEEQRQ----KDLERIKDYCSLEDQVRDHA-AKNYSP-DVFALTSKLLRLNPEYYTVWNVRRRCLISGLQILQKELH-FTLLESPKCYWIWSYRLWILKQVELGLTSKMLLRDQRNFHAWGYRRHVVDKSLVESEFEFTTKKIEQNLSNFSAWHSRSKLIPR--LARKAFFEELGKIGEAI--NVGPDDQSLWYYHQFLMYLRREIEGIQEYEALFDYTLYLCQLGSLKKLDPM-RSGRWADL Sphar --------------------------------------------------------------------------------------------------------------MDIIA----RENR-----------------KHETAFSAKKIEDNFSNYSSWHYRSKLLPQ--LKADILLN----------------------------------------------------------------------- Spipu1 HHHQKKVKSAEAVERQREKNQKKIAEYRALCAQVQQKR-NDKYDD-ETFQLTTKLLSINPEYYTMWNLRRQILLEK-ALCSSELR-FALKVNPKSYWVWNHRRWILENMELRLLEAMLDLDARNFHGWNYRRYVVA-RTPQEEFDFTTTKINQNFSNYSAWHHRSKFLPQ--AELTKVIDEFELVRNAI--YTEPADQSAWLYQRWLLPLLRKIRAIRYFTWVVYFILTP--FLDKRDRGPVILSHLYLLI Sporo1 -HGVKRSRSVEVERKKCDKQREMINEYTTLVQQLQTKM-KAQYTH-ESLGLTTKVLGMNPEFHTGWSMRRTILLKGLALLNQDLE-LTLKLNPKNYSVWEHRKWVLETLEIKMVELYLEKDGRNFHSWDYRRYLIS-----SELSFTTRKISSNFSNFSAWHYRTKLLTK--LTKRKL--EFELVQQAI--WSDPNDQSAWLYHRWLIIVRRELGGIQELDSLVHYKRLLVGLEKLQEVDPM-RRNRYRDI Stehi1 MHGVRRVRSREAQEAKQERDKAKLVAYLALTDDVLARK-KSQWSQ-DAFDLTSRLLSTNPEFYTVWNYRRNILLRGIELLTNDLA-MTLKAHPKVYWIWNHRRWCLESIEMGLVEKMLEADARNFHAWNYRRYVLA-----AELGFTTKKIESNFSNFSAWHQRTKILSS--LATLQQ--EFDLVQNAM--YTDPNDQSVWLYHRWLVLLEREIVVIQEMESLVHYKQLLLRLDQLESIDPQ-RRRRYQQL Tapde11 GHGVKRINDADAYAAQQARNAKKADLYIDLSHQINLLR-QAEYSR-DSFDLTTKLLMINPEYYTIWNYRREIMLNGLELLNTELK-RLLQDYPKVYWIWNHRKWCLSQCELLLVTKMLEQDARNFHVWEYRRYVVS-SKAEREFEYTTAAINSNFSNFSAWHNRTKLVPK--LARRQE--ELELIKGAI--YTDPDDQSVWLYHRWLLHLTNELQMIDETYAKVHYALSLQRMTVLENTDTL-REGRYRDW Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MHGIKRSRSSQAEVIRREKEAGKIAVYGSLQAEILTLK-KNKYTP-DALKKTTELLDLNPEFYTIWNYRRHILLH-LSLLTTDLR-LTLQVHPKVYWIWNHRKWCLENVELAVIEKMLDADARNFHAWDYRRYVLS----LDELRYTKKKIESNFSNFSAWHLRTKILGG--M-VEKQKDEFELVRQAL--WTDPGDQSGWLYHRWLIRLREEINSIREMNALAQYDILLSSLRRLGKVDVF-RKQRYRDI Trire2 -HGVTRTTTEEQRL----QDLEKIEKYRSLENQIRAQV-AAGYDL-HLFDLTTKLLRQNPEYYTIWNVRRRCLLACRDVLQTEIA-FTLMEFPKCYWIWNFRQWLLAQAELGLVSKMLNKDQRNFHAWGYRRLVVAKSMAEDEFAYTTKMIRQSLSNFSAWHNRSQLIPK--VARAEFLTELDLVRDAL--NVGPEDQSLWYYHQFLVYLKHEIEEIKDYEALSDYTVALQRLSKLRALDPM-RTGRWNDV Umbra1 VHGVKKVKNEELAQARKQKEAVKIKEYNDLVSRCKEEV-EAKFEF-STLRLTSDILQLNPDYYTIWNYRREILLQGIQVLQQELE-FFIRINPKSYSMWNHRRWCLSVMEFKLVGKMLDLDARNFHGWSYRRNVVA---DTKEFEYTSTKIKQSFSNYSAWHYRSKVLPS--IERTAVGKELDLIKNAL--YTEPDDQSAWLYYWWLV-------------TMPSPL------------------------ Ustma22 MHGVKRQPTAEARAARKAKEAAKLAAYLEVEQTFFEYK-RSAKDT-TALHHTTKLLTLNPELYTVWNYRRQVLLH-MQLLEDDLA-LTLRAHPKVYWIWNHRMWCLTQYELKLVEKMLDLDARNFHGWNCRRTIIQVSLAENELAYALRKIESNFSNFSAWHQRTQLLPH--VQMHVY--EFERVKHAM--YTDPSDQSVWFYHRWLVVLHSEIGVIEEAISLAHYNTLLATLQQLIELDPD-REHRYRDL Walse1 MHGIKRQNDPD------DKISKSIKDYRSAESKVLDLR-KNDKTP-ESLDSTTHLLDLNPEYYSIWNYRRIVLLH-LEKLSYELV-FTLKRFPKVYWIWNHRTWALETLELKMVDSLLKLDARNFHAWGYRRQLLT-----KEKQFTLTFIESNFSNFSAWHQRTKILKQ--L-------EFDLVRQAM--YTDPSDQSVWLYHKWLIVLNRELESINELESLAHYNKLLY-LDKLISIDPD-RRNRYLDS Zygro1 MHGVKRKQTQELLKQKKEQDRKRITQYRGLVDKLLDSR-DSKYNM-EVFKETTQLLRINPEYNAGWNYRRDIIEHL-EFWEDELA-FSLKDYPKVYWIWNHRKWTLENHELAIVSKLLQMDPRNFHGWHYRRILVAQSRDGEELQYAIDNTNKNISNYSAWHQKATLIPK--M--KKFIQEFTYITNAI--YTDAEDQSVWFYIEWFVKLQELQENILALKVLIVLEDVQRNLAQLIEADPM-RKNRYLHL [Cluster2143.fasta_al_trimmed; alignment length = 153] Allma1 MTAIWRVPVTLLQLDSVYVYYGVQVGAGLA-PLKEFAEFKV-TDAL-LPGHQLTAAHYQVGQFIDVRGVTVGKGFQGVMKRWGFKGQPATHGVSVTHRSLGSTGQCQDPG-RVFKGKKMAGHMGTTLNLQIVKIDNVLYVKGG-VPGITIRDA Ashgo11 MMPYFRMAATVLEMNNVEVYWACQVGYGNK-PKEKVTEFRVKNEGL-LPGTLLKPSFFSPGQYVDLRSVSKGKGFQGVMKRYNFKGQKASHGNSLSHRKGGSYGQNQTPG-RILPGKKMPGHMGTIQNVQVLEVQGVIIVKGS-VAGVKVQDA Aspfu1 MTAVYRIACTVLQLDRVQVYNAVQVGAGWK-PKRHVYEFRVKDSGL-LPGQTINADWFQEGQYVDARSYSKGKGFAGVMKRHGFHGQDRSHGVSLTHRSLGSAGPSQGGGSRVYPGKKMAGNMGTVQNLKVLKVDGIVVVNGS-VSGVRIQDA Aurde31 MTAMWRFPVTVLQLENCQVYHAVQVAATDK-PKQIVKEFAV-SDAH-LPGTKLNAIHFVPGQYVDVQAKSVGKGWAGAMKRWGFHGLAASHGVSVSHRSAGSTGQHQDPG-RVWPGRKLAGRLGTQQHLYVVRVDNLVFVRGS-VPGVFVRDA Batde5 MTSIFMVPVTVLEVSNCQVKHMVEVGAVSQ-PKKKITEFDV-TDAC-IPGVRLFASHFVAGQYVDVQGKTMGKGFQGVMKRWGFGGQPASHGVSISHRSLGSIGQCQDPG-KVWKGKKMPGRMGTTQNLKVIKIDNLIYVKGG-VPGLRVTDS Botbo1 MTAMWRIPLTILQIENCQVYVAVQIAASDR-PKRIVKEFEV-TDAL-LPGTTLSAVHFVPGQFVDVVANSLGKGFAGVMKRWNFKGLRASHGVSVSHRSAGSTGQHQDPG-RVFPGKKMAGRLGTQQNLFVARIDNIIYVKGC-VPGVYISDA Botci1 MTALYRTPCTVVQLDRVQVYYAVQVGAGWK-PKRYMAEFRVKNSGL-LDGRSIGAEWFIEGQFVDARANR----------------------------------------------------------------------------------- Caeel MLPQWRILCTVLEVDENHVMWRVTVGAGND-VKEKLGCFLV-TDA--LPGQPLDARHFGVGQYVTATGKTIDWGFQGGMHRWGMRGQP-TRRTTKSHRRIGSVGSVGDA--RIWPGKRMPGHMGTVSGLEIVRINQVIYVKGS-VPGILLKDC Canalb1 MITWFHIPATVLEVDSCEVYTAVIMGTIDK-PKQKIGEFKIRSSKL-IPGTELTADYFSVGQKVDVKGVTKGKGFAGVMKRWGFSGGRATHGTSKAHRTPGATGGNQNPG-RVFPGKKMPGRMGTGFNLEVLHTDGILIVKGN-VPGIKVSDA Cangl MMPYFRIAATILQFNNVEVYVACQVGYGNR-PKEKVTEFRVKNEGL-LPGTHIKPDFFTEGQYLDVRSVSKGKGFAGVMKRHNFKGLRASHGTSVMHRHGGSYGQNQDPG-RVLPGKKMPGHMGTVQNVKILKVDNVIWVKGA-VPGVKIQDA Capow MMHTWRLPLTVLQISDAAVYTALQIAAGEI-ARKHIHEFRV-TNAL-IPGTRLYAAHFIPGQHVDVLANTKGRGFAGVMKRHGMKGSPASHGHSLVHRAMGSFGGGGGMG-RVYPGKRMAGHMGMHHNLLVYRINNLVYVKGS-VPGVYLRDA Catan2 MTAIWRIPVTLLQLDNVYVYYGVQVGAVPAFPLREYAEFKV-TDAL-LAGTQIAATHYEVGQFIDVTAKTVGKGFSGVMKRWGFGGQGATHGVSLTHRHPGATGACQDPG-KVWKGKKMAGRHGTVLGLQIVKIDNVLYVKGS-VPGIKVRDA Cioin VHPIWYANCTLIQIQDCHVTAAVIIGGKNA-VKAKCFRFLI-SNAALKPGTEITAMHFKPGQFVDCTAQSIGYGFQGVIQRWHFAGGHARKDKKWM-RRPGSIGGSQ-IG-WVMKGKKMAGQLGITRGLKVLRINNVLYVKGR-IAGVKIADS CocheC53 MTSLYRTACTVLQFDRNQVYWAVQIGAGQK-PKRWVAEFRVKGEGLQVGGESVGAGWFREGQWVDVRGVGRGMGFAGGMKRHGFGGQPASHGQSLMHRGMGSAGGSQGSGSRVLPGKRMPGNMGTVKNLRVLQVDGLVVVTGC-VPGIRVQDA Coere1 MCGMWRVPVTVLQLENVQVLARLQIGCGTR-PKAKLFEFPI-TDAA-LPGTELTAEHFVAGQLVDVTAPSLGKGFQGVMKRWGFSGGRASHGNSLAHRTLGSTGNIN-PG-RVYPGKKMPGRMGTVIRLPVMKVDNCIWVKGS-VPGVKVRDS Conco1 ---------------DCQVYTALQLGCADM-PKHKLFEFEV-TDAV-LPGTLLNAAHFVPGQFVDVTAPTIGKGFQGGMKRHGFGGLRASHGVSLTHRSIGSTGARE--G-KVPKGKKMPGRMGTTLNLRVAKIDNLIYVKGA-VPGIKVRDS Conpu1 MTALWRVPVTVLQLENCQVYHAVQVGASDR-CKYAVREFPV-TDAH-VPGTTLSAMHFVPGQYVDIIANSIGKGFQGTMKRWNFKGLRASHGVSVSHRSAGSTGQHQDPG-RVWPGKKMAGRLGTVQNLAVIRVDDLVFVKGA-VPGVMVRDA Copci MAALWKFPVTVLQLDNCQVYHAVQVASTDR-PKRYVKEFPV-TDAH-VPGTTLNAAHFVPGQYVDVVAKSIGKGFQGGMKRWGFHGLAASHGVSVSHRSSGSAGNSQDPG-RIYPGKKMAGRMGTVQNLAVVRVDNLVYVRGA-VPGVYIRDA Croqu1 MTSFWRVPVTVLELEDVQVYHAVQVGCSDR-PKHRVAEFKVSDRAL-VPGTRISSAHFVPGQFVDVKANSKGKGFAGVMKRWGFGGGNASHGSTKHHRKAGSTGQHQDPG-RVWPGKKMAGRMGTVRNLLVARIDNVVYVKGQ-VPGVRISDA CryneH991 MTALWRWPVTVLQVDANQVYHTLQIGASPR-PKYRLKEFQV-SNAV-VPGTELSAGHFVPGQFVDVQGATIGKGFQGVMKRHGFRGLKASHGTSVKHRSPGSIGQNQDPG-RVIPGKKMPGHMGTTQNLLIHRVDNLLYVRGC-VPGLYVKDS Crypa2 MT-GYRFPCTVLQMDQCQVYCAVQVGCGEK-PKEHLVEFQVRGDGL-APGVQLLPDWFHKGQWVDVRAQSRGMGFEGGMKRHGFSGQEASHGNSKNHRTIGSAGASQGAGSRVLPGKKMPGRMGTVQNLAVLRVDGIIVVKGC-VAGVQIQDA Debha1 MITWYQFGATVIEIDNCEVYTSVLLGQCDK-PKKHIGEFRIRDSGL-IPGTELTADYFAVGQLVDVKAITKGKGFAGVMKRHGFKGLKASHGVSKAHRSAGSMGATQTPG-RVLPGKKMAGRMGTVFNNEVLHADGFIVLKGQ-IPGVRISDA Dekbr2 MTCYFRIPATVLEVDQCEVYYAVQMGAGFR-PKAFVAEFEVKSDGL-IPGTEIKADRFKVGQLVDVISHCKGKGFAGGMKRWGFHGGRATHGVSLSHRTIGSTGQNTDPA-RVFPGKKMPGHMGTIFNLEVLDVNGYFLVKGC-VSGIKVRDA Dicdi MLTTYAYPVTVIQLPNNQVVDMIQVGADEI-PKRVLMEFRV-TNAMNLEGTPILPKHFLPGQLITVKGTNTGKGFAGGMKRWHFSGQPATHGVSLTHRAIGSTGCRQTPG-RVFKGRKMPGRLGTVKNLQVLKINNCLLVKGA-VPGLKITDS Dmel QYPLWRIRTTLLQIVDNHVRGCILVGSETT-PKKNLARFIV-SEAQLAPGTPLNVNHFRVGDFVDVRGKTVDHGFQGVVKRHGFKGMPASHGVTKTHRRAGNIGGGGEKG-RVWPGTKMPGHMGIIKGLRVWRINNVMWVQGSSVAGVYIYDT Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MTSLYQHGATVLHMNEVQVYTALKVGAVNK-RKHVTGEFRC-SEAL-LPGHVLEATHFYPGQYIDVTSVSVGKGFQGPMKRWNFGGNPATHGVSKSHRSHGGTGACQDPG-RIFKNKKMAGRMGTAINLQVLKVDNLLYVKGA-VPGVRVRDA Fomme1 MTALWRCPVTVLQLENCQVYHAVQVGASDR-MKYIVKEFPV-TDAH-VPGTALSAFHFVPGQYVDVIANSIGKGFQGGMKRWGFRGLRASHGVSVSHRKIGATGGHQDPG-RVWPGKKMAGRMGTQQNLEVVRIDDLIFVKGA-VPGVLIRDA Fusgr1 MTSMFRVPCTVLQLDQVQVYWAVQIGQGSR-PKAELAEFKVRDDGL-LPGVQILPDWFKKGQYVDVKGRSRGMGFAGGMKRHGFSGQEASHGNSKNHRTIGTTGPSQGSGSRVMPGKKMPGRMGTVQNLKVMMVDGIVLVGGP-IAGVRLQDS Galma1 MTALWRVPVTVLQLENCQVYHAVQVAACDR-PKRIVKEFPV-TDAL-VPGTTLSAIHFVPGQFVDVVANSIGKGFQGGMKRWGFHGLAASHGVSISHRSSGSTGQHQDPG-RIFPGKKMAGRMGTTQNLPVVRVDNLIFVKGT-VPGVLVQDA Ganpr1 MVTLWMIPVTLLHVPTTEVHSMVQLGVGEA-PKQKLVGFTV-TDAV-IPGTKLTVGHFVAGQFVDVKGKSIGKGFQGVMKRWGMHGLRASHGTSLKHRSGGSIGANQDPG-RIWKGRKMAGKMGSVQNLKVIKLDSLIYVKGG-VPGVRVLDA Gloin1 -------------------------------PKKKLLEFHV-TDAV-LPGTEIKAAHFVPGQYVDVTAPSIGKGFAGVMKRWNFRGLPASHGTSLAHRSAGSTGQNQDPG-KVFKGKKMAGRLGTVLNLKVLKIDNLIYVKGG-VPGVRIRDA Hisca1 MTAIFRIPCTILQLDRVQVYYAVQIGCGWK-PKRHIHEFRVKDNGL-LPGEMINANWFQEGQYVDARSNSRGMGFAGVMKRHGFHGQDRSHGVSLTHRSMGSSGPGQGGGSRVYPGKKMAGNMGTLQNLKVLKVDGIVVVNG----------- Klula1 MMPYFRIAATVLQLDNNEVYWACQIGYGNK-PKEKVTEFRVKDSGL-LPGSLIKPSWFKPGQYVDLRSISKGKGFQGVMKRYGFKGLKASHGVSVSHRSGGSYGQNQTPG-RVLPGKKMPGHMGTIQNVQVLDVNGTVLVKGS-VAGVKIQDA Lacbi2 MTALWRYPVTVLQLENCQVYHAIQVAASDK-PKRIVREFPI-TDAH-IPGTTLSAVHFVPGQFVDVVANSIGKGFQGGMKRWGFHGLAASHGVSVSHRSSGSTGQHQDPG-RIFPGKKMAGHMGTTQNLAVVRVDDLIFVRGA-VPGVLIRDA Lenti61 MTVMWRFPVTVLQLENCQVYHAVQVAASDR-PKRIVKEFPV-TDAH-VPGTTLSAIHFVPGQFVDVIAKSIGKGFQGTMKRWNFKGLRASHGVSVSHRSAGAIGAHQDPG-RVWPGKKMAGRLGTTQNLAVVRVDDLIFVRGC-VPGVMIRDA Malgl1 MTTMFRVPATVLYVDSNQVYMALQVAASDA-PKRVIKEFRV-TDAM-LPGTQLSAAHFVPGQDVDVRAITRGKGFAGVMKRHNFAGGNASHGASLAHRTPGSVGNNQDPG-RVWPGKRMPGRMGTVQNVRVLRIDELIFVKGQ-VPGVFVQDA Mellp23 MTSFWRVPVTVLELEDVQVYCAVQVGCSNR-PKHRVAEFQVTDTSL-VPGTEISSAHFVPGQFVDVKANSKGKGFAGVMKRWGFSGGNASHGSTKHHRKAGSTGQHQDPG-RVWPGKKMAGRMGTVRNLLVARIDNVVYVKGQ-VPGVKISDA Mnele ETRSFVVVSTFLEIQDNYVRLSMRLAAFDA-PKQVTHSFIV-TEQA-LPNYKLDVSHFFAGQYLDIRGLTINRGFQGVIRRWGYKGQ-GKFGRTKTHRRPGSIST-QGLA-RVLKGKKMPGIMGTTRNAQILYANRYIVVEGP-VQGLFLSDS Monbr MTQTWLIPMTVLQVEDCQVYEALILGAETI-SKRHMEEARI-SEAM-LPGYELSCEHFEPGQLVDVRGTTIGKGFAGVMKRHNFKGMPATHGVTKTHRRMGGFGGGQDPG-RVWKGKRNAGRMGWQRNLAVIRIDNLIMVAGS-IPGVLVRDA Morel2 MTAMWRIPVTVLQLEQCQVYTALQIGSTDR-PKRKLVEFEV-TDAV-LPGTELVASHFVPGQFVDCSAPTMGKGFQGAMKRHGFGGQPASHGTSLTHRSLGSTGQRKDPG-KVFKGKKMAGRMGTVQSLKVMKIDNLIYVKGA-VPGVKVRDA Mucci2 MTSVWRMPVTVLQLEDVVVYIALQVGCSPK-LREKLYEFRV-TDAV-LPGTELTAEHFVTGQYVDVTAPSIGKGFAGVMKRWNFKGLPASHGVSLTHRSGGSTGQRKWPS-KVFKGKKMAGRLGTVQSLKVIKVDNLVYVKGS-VPGVKIKDA Mydma VSVLWCHMVTLVQIKDCQVITQMLLGCCDI-PKQYWTGFPV-TNALLFPGTKITSLHFQPGQHVVVQGISIDKGFQGVMRRWGMKGQPQSHGQTLTHRKMGGTGGGQDPG-RIFPGKHMAGHVGTVGPLRILRINNVLYIRGG-IPGLKIKDS Neucr2 MT-VFRIPCTVLQLDRVQVYWAVQVGLGER-PKQTLAEFKVRNDGL-LPGVQLFPDWFHVGQVVDVRGITRGMGFAGGMKRHGFAGQEASHGNSLNHRTIGSVGGSQGSGSRVLPGKKMPGRMGTVQNLPILMVDGIVVVKGA-VAGVKVQDA Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MTAIYRIPCTVLQLDRVEVYYAVQVGAGWK-PKRHIFEFRVKDAGL-IPGQSIEAGWFQEGQFVDARSNTKGKGFAGVMKRHGFGGQDRSHGVSLTHRSMGSSGPGQGGGSRVYPGKKMAGNMGTVQNLKILKVDGIVVVSGA-VSGVRIQDA Phybl2 MTSMWRLPVTVLQLEDVIVYSALQIGSTTK-LREKVAEFKV-SDAI-LPGTELSASHFVTGQYVDITAPSIGKGFAGVMKRWNFAGLPASHGVSLTHRSGGSTGQRKWPS-KVFKGKKMAGRLGTVQSLKVLKVDNLVYIKGS-VPGVKIKDA Picst3 MISWFQFAATVIEIDSCEVYWSVLLGQIDK-PKQNIGEFRVRDSGL-IPGTELKADYFSVGQLVDIKAVSKGKGFAGVMKRHGFKGLNASHGVSLSHRSAGGMGGNQDPG-RVLPGKKMAGRMGTVFNNEVLHADGILVVKGQ-IPGVKILDA Plicr1 MTAMWRYPVTVLQIENCQVYHAVQVAASDR-PKRIVKEFPV-SDAH-VPGTTLSAIHFVPGQFVDVVSNSIGKGFQGAMKRWGFKGLKASHGVSVSHRSAGSTGGHQDPG-RVWPGKKMAGRLGTTQNLVVVRVDDLIFVKGA-VPGVLIHDA Polpo MTTVWAIPVTVVHLPNNQVVDALQVGADEI-PKRILMEFPV-TNAF-LPGTQITPRHFVPGQLVTIKGVSTGKGFQGGMKRWNFSGLAATHGVSVSHRSIGSTGCRQTPG-RVFKGKKMPGHLGTVLNLQVIQCNGTIMLKGA-VPGIRIIDS Pucgr2 MTSFWRIPVTVLELEDVQVYDAIQIGCTDK-PKQKVTEFVVSNQCF-SPGTSISAAHFVPGQFVDVKSNSKGKGFAGVMKRWGFSGGNASHGSTKHHRKAGSTGQHQDPG-RVWPGKKMAGRMGTVRNLLVARIDNLIYVKGQ-VPGVRVTDA Punst1 MTAMWRVPVTVLQIENCQVYHAVQVAASDK-NKAIVREFPV-TDAH-VPGTTLSAIHFVPGQYVDVVAKSIGKGFAGTMKRWNFKGLRASHGVSVSHRSAGSTGAHQDPG-RVWPGKKMAGHLGTTQNLRVIRVDNLIFLKGC-VPGVMIKDS Rhior3 MTSVWRMPVTVLQLENNIVYTALQVGCTPK-LRQKLFEFRV-TDAV-LPGTELTASHFVEGQFVDVTAPSIGKGFAGVMKRWNFKGLPASHGVSLTHRSAGSTGQRKWPS-KVFKGKKMAGRLGTVQNLKVVKVDNLLFVKGA-VPGIKIKDA Rhoto1 MTALWRIPVTVLQLDAVQVRHTVIVGCSPR-PKMRLAEFEV-TDAL-VPGTVISAAHFVPGQHVDVQAPSIGKGFQGPMKRHGFRGLRASHGVSISHRSHGSTGQHQDPG-RVWPGKKMAGRMGTTQNLMVERVDNVVYVRGH-VPGVRVTDA Rozal11 MMSIYRIPFSDNQVFDKVVLYFQQVCAELK-VRRYLKTFQV-EDAL-LPGTPLYAAHFTAGQFVDCVSKSIGKGFQGVMKKWGFKGMPKTHGTTKKHRHPGSIGP-MGLG-RVWKGKKLPGRMGATFHVQVMKVCNCIFLRGS-IPGVYLHDS Sacce1 MMPYFRSAATILEVNNVEVYFACQVGYGSR-PKEHVAEFRVKDKGL-IPGTLLKPSFFKEGQYVDVRSVSKGKGFTGVMKRYGFKGLRASHGTSIMHRHGGSYGQNQDPG-RVLPGRKMPGHMGTIQNVKVLKVDNVIWVKGS-VAGVKIQDA Salro MTQTFRVPLTAFQIEDLQVYSAMRLGAVNL-PKQHVAEFRV-TDCI-LPGTHISCSHFIPGQYVDVQGVTIGKGFQGVMKRHNFKGMPASHGVTLTHRKAGGLGGGQDPG-RVWKGKRMEGRMGYQFGLQVYQIDNLLYVVGS-APGVKIRDA Schco3 MTTIFACPVTVLQLENCQVYHAVQVAASDK-PKQVVKEFPV-TDAV-VPGTTLSACHFVPGQYVDVVANSIGKGFQGGMKRWGFGGLAASHGASISHRSLGSTGQNTDPA-RVWPGRKMAGRLGTTQNLLVERIDNIVYVRGA-VPGVQVRDA Schpo1 MTNAWQVPLTILQFDRVQAYYAVQVGSGIR-PKMHVREFRVRDSGL-VSGTIFTTDYFKPKQYVDVKGITKGKGFAGVMKRWGFSGGNASHGASLSHRTPGSTGQNTTPS-RVLPGRKMAGHMGTVKNLLVWAVDECILVKGS-IPGVYVTDT Sorma MT-VFRIPCTVLQLDRVQIYWAV--------PKQTLAEFKVRNDGL-LPGVQLFPDWFHVGQRVDVRGITRGMGFAGGMKKHGFSGQEASHGNSKNHRTIGSVGGSQGSGSRVLPGKKMPGRMGTVQNLPVLMVDGIVVVKGA-VAGVKVQDA Sphar MLTVWILPITILQLEDNQVNAALQIGAREV-LKKKLLDFRI-TDAT-LPGTPITAAHFVPGQFVDVCATSKGKGFQGGIKRHGMNRQPATHGNSKSHRKMGGTGGCQDPG-RVFPGKRMPGHMGTKLNLRVYRVENAIYVIGA-VPGVRITDS Spipu1 MTAIWLTPVTVLQIVDCEVSYVVELGAVNH-PKRMMTGFKV-TDAC-LPGTKIKAAHFVPGQYVDCQAKSTAKGFQGVMKRWGFKGQPASHGVSLSHRSLGSTGNRHDPG-RVWKGKKMAGNMGTVQNLRVLKIDNLLYVKGA-VPGVRIKDA Sporo1 MTALWRVPVTVLQLDATQVRHTVIVGCSPR-SKMKVAEFQV-TDAR-VPGTEISAAHFVPGQHVDVQAPSIGKGFQGVMKRHGFRGLRATHGTSISHRSHGSTGQHQDPG-RVWPGKKMAGRMGTTQNLQVERIDNVLYVRGA-VPGVRVTDA Stehi1 MTAMWRFPVTVLQLENCQVYHAVQVAASDR-PKRIVKEFPV-TDAH-VPGTTLSAVHFVPGQFVDVVSNSIGKGFQGGMKRWGFKGQRASHGASLSHRSIGSTGGHQDPG-RVWPGKKMPGHMGTTQNLTVVRVDDLIFVRGC-VPGVMVRDA Tapde11 MTGIWKIPVTILQLDRTQIYNAVQVGAGLR-PKQRIAEFRT----L-LPGTILTASHFQPGQYVDIRAVSKGKGFAGVMKRYGFKGLRASHGVSISHRSAGSMGQSQDPG-RVLPGKKMAGRMGTVQNVKVIEIDGTLMVKGP-VPGIMIQDA Thetr MLPYWRHPATVVHFPDNVVTSRLVVAAAKA-PRRKMVEFAV-SDAV-LPGTELSAAHLLPGQYVDVRGVTRGKGFAGVMKRYNFKGQSASHGTSVAHRHGGSTGGSQGPG-KVWKNKKMPGRMGTSQSLKVLKVVNVVLIRGS-LPGLVVSDA Treme1 MMSVWRWPVTVLQIDSCQVLHSLQLGASPR-PKYRLQEYQV-TDAV-LPGTELSAGHFVPGQYVDVTGVSIGKGFQGVMKRHGFRGLSASHGVSLKHRSGGSTGQNQDPG-RVIPGKKMAGHMGTVQNLLVHHVDNVIYVRGC-VPGVSVRDA Trire2 MTSIFRVACTVLQLDQVQVYWAVQVGLGAR-PKAELAEFKVRGEGL-LPGAQLLPDWFQLGQHVDVRARSRGMGFAGGMKRHGFAGQEASHGNSKNHRTIGSTGPSQGSGSRVLPGKKMPGRMGTVQNLKVLKVDGVVLVSGP-IPGVRLQDA Umbra1 MSTFWRMPTTILQLEDVQVYTALQVGCTNK-PKQSVAEFRV-TDAL-LPGTILNAAHFVPGQYVDVTAPSIGKGFAGVMKRWNFAGLPASHGVSLAHRSAGSTGQRKWPS-KVFKGKKMAGRMGTVQSLKVLKIDNLVYVKGC-VPGVKIKDA Ustma22 MTSFFRIPATVLQVHSNQVYTALQVAAVDT-GKKIIREFPVSSDAL-VPGTQLSAVHFVPGQSVDVRAITRGRGFQGVMKRHGFHGLRASHGVSISHRSHGSTGANQDPG-RVWPGTKMAGRMGTIHNLLVVRVDDLIYVKGN-VPGVTLQDA Walse1 MSFIYKVPVTLIEIEKNRVHHFVQLQSRNQ-----LKEFPV-TNGI-IPNTELNVSHFIPGQFVDIQGTSNGKGFAGVMKRWNFKGLRASHGTSISHRSQGSTGQNQDPG-RVFPGKKMAGRMGTVQNLKVIRIDNLLLVKGA-IPGVYIKDA Zygro1 MMPFFRVACTVLKMDNVEVYFACQVGYGSK-PKERVSEFRVKNDGL-LPGTLIKPSFFNNGQYVDLKSICKGKGFAGVMKKYHFAGLRASHGTSIMHRHGGSYGQNQDPG-RVLPGKKMPGHMGTIQNAQVLKVDGVILIKGS-VAGVKIQDA [Cluster2147.fasta_al_trimmed; alignment length = 247] Allma1 SPHALFLSAVAG--DAAAAAVTRLTTCA-QRLFSTNEALDDVKTTDLPL-LLVTIQSQFQQFMTQCDTY-D-LI-PRDERSYM----RRNFKIARFKASRQRESLLAFASRRGDD-ADADDEAIARDKAVDELINLERAHLDRM---DSADRLDGPPLLDKGGRLR-PFTITSQRAALQDQVFRPGLPTMSLDEYLEAEMARGGILPR-AEPAPVRNESADRKTYKARNWDAFTDDNPRGWGNRGGN Ashgo11 TVRERYRALVAA-YQAEVRTLEGLAEVT-LGLFSRNEGVEDVATGTLEL-LALEAVQFAMQFLVGLQDY-G-VLDEALSKRLDGAHLRREAKIAQFRRVRELEAQLDLEARRA------ADEELERRECFGELEGWEMELLRN-DSQEYTEKLESLQLLSKYGKLR-NFTLVDQRDRVKERVLGYGGPTMTVEEFLEQEFESGRVLQG-GEEPEE----QDKQTYKEREWDEFKEANPRGSGNT-MN Aspfu1 SLRSLFTAAKAS-YREDVATIAKFEECQ-LSLFSSNEPLEDIATGDIQY-LTVRALELYEKYLSRLDDY-G-LLNDNEKKLHEDAATRREVKLSRFREEKELKQRLEFSNNQS-------DDEDVRKQAFQSMDLLELSMLSAIES-GYSERLD-PPLLSKEGKLQ-PFTLLDRRTQLQQGVFRPGLPTMTIDEYLEEEKRRGGIIE--GGEKSGMKEEADEETMKARAWDEFKEANPRGSGNTL-N Aurde31 -----------T--QELVSALSDLHALS-LGLFSSNETLEDLTARDMLY-LFVNAQRLLEQFIRSVDQY-S-VIPDEDKALWSDPSRRRETKIKQYKHEKAVRGMIDLRASRG--------DDGARKKAQAQLESMELELLRSMEE-DSTWRLD-TTLLDSKGKLR-PFTILSDRQRLQSEVFRPDLPTMTIDEYLEEEQRRGNIISG-GGPASLEQPTSEEKRQKDENWARYTDTHRKGEGNTM-N Batde5 -LKEQYSKAISE-YQKMVQAIGLFSECS-LSLFSSNEILEDINTGDLRF-ILLNANEHLRAFLGRLEEY-E-ILTKSDKQYLLSADLRRNEKIARFKMERDVKIQLKLTEQ--AN--SGEVDDVERQKSIASLRMIEKEMLEFASG-SSADRVESRVLMDAKGKLR-PFIVRSQREAIKENVFKSGLPTMTIDEYLEREIARGNFLSG-GTE----RPEIEAEMYKARAFDEFKDENPRGWGNR-HN Botbo1 SLPELFKSALTA--QESIRSLANLKVLH-LSLYSRNETLEDLSTRNLAF-MFVKAQSHLRQFLATLDDY-E-IVPNDEKSLFRDPASRRELKIKQYRKEKEIRDKLNARARRDDD--DEDRD---REQALSQLESMEFELIASAQR-DNTWRLD-APLLDASGKLR-PFTILSERARFQSEVFRPDLPTMTMDEYLEEEMRRGNIISG-GGPQSEAQLTSEEKRREEERWSVFTEKNPKGAGNTM-N Botci1 SLKTLFSSAERK-YQDDVSALTAYQECR-LALFSPNETLEDINSSDIQYILVIEAKKCYEAFLTQLGYY-E-MLSTAEKKLYADPTARRNVKIANFKMEKELKKKLDLAANPA-------DEDAIRENAFQSLESIELEILAMAPDAGYSDRLD-MRILSTGGKLR-PFTLLESRQALQKGVFRPGLPTMTIDEYLEEERARGGIIEG-GGEASGIIPDMDEETEKARRWDEFTEDNPKGAGNTL-N Caeel SLQALYDPSKK--LQPRITGIDNLQLVQ-MRLFSSNEQIEDVPTNSLPY-LLVKSKIYMRNFLDRLR---D-LWEDEDTE---AVEEIRRLKLERHKKKKMAELRIQ----------KQLDEQNLRERCYEELQAIELPLLKMM--------AERAS---PATKLK-PFIIT--RDAQQKQVFGLGIPAMSVDEWYHQK-----FGHNPQNAPQSSAPADDEARAKAMRWDEYKDDHRRGWGNMH-N Canalb1 TVAERYKLAIQS-YQKRLKLISEFKLIQ-LSLFSDNEQIEEISTKYIPF-LNLLGQRFIFTYLENLMNY-DDILTLEQSKKLKNPMNKRQEKIDNYKLEQELLKKLSLNQ---EE--DINDEEIIRTKSFNLLESIELQVLQHRDDYGFTTKLESIPLINKQGKLQ-PFTITSQRQKLKEKVFGTGLPSMTVEEYLDYELANGKMLKD-EVKDNNPANKSEAEEEK-RRWDDWKDENPKGAGNMKAN Cangl TILEQFRGIQGE-YQKLLGTIQELLDLHKLSLFSSNETVEDIATSSLLY-LSLKAIQLFMQYLSTLQDN-E-ILDESISKKIDGAQLRRQEKIEMHKQNTAVAQQLRLEGKVS----Q-EDDELLRKETFDEIEKIEKELLSNFDPTGYTDKLETLNLLSKHGKLR-NFTLVDKRSELKSKVKGYGGPTMSVEEFLEQEWEQGRVLQG-GEEPTKEEIEQDKETYKAREWDEFKEENPKGSGNT-MN Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 PLTQLFFDALAT--DAAIAARDTLLHCS-ARLFSPNEDWDDVATSNLPL-LLTRVVGHWHAYLTIASRF-G-LASPGDV----NAATRRNEKIARFKAGKERQARMAAAQRKADG-VDDDDEVLSRDKAKDELEMVELPMVERMED-DLASRLDGVRLLDAQGRMR-PFTLVSQRAIEQGKVFRPSLPTMSIEEYIDAEMERGGILPK-QDPNDQKQDSADRRTYKKREWDAFTDDNPRGAGNRTGT Cioin KIVDLFNEVWS--IQGLIDTLATLSVLQ-LSMFSHNEEVDEISTQDIRY-LMLKSREFYVEFLKICRDY-G-IKPASDEEALLSMTRAREAKIEKYKQSKLMEQQLS----------ELQDEQC-RKHVIEEMGNMEISMLKRM----PKSQIEEDR-LRESIKMQ-PFILT--KDKLQAAVYGAGLPTVTLDEYYEREAAAGRMPDQASKPASDKK--SDEKLKKKREFDDWKDTHRRGAGNRK-N CocheC53 SLRGLFSKAERT-FQEKLATIATYEECQ-VSLFSPNESLEDISSTDLQY-LAIRARGYYERFLKLLDSY-D-MLGKADTKLLEDAAARRDAKIARFKEEKELKRKLELRQNPK-------DEQVVRDQTFASLESMELHIISLAKD-GYSERLD-GQILSSDGKMR-PFTLLDSRQSLKKGVFRPDLPTMTIDEYLEEERKRGGIIEG-GGPQSGIQPEADAETMKQRAWDEYVEANPKGSGNTL-N Coere1 PLGLGFARAQQE-YQNMVALVRQLRLCS-LSLFSSNESVDDYSTSELKL-ILAMALDHYQRFISTCQDL-G-ILSSEKQQLSLNPGQNRMQKIERFKQLRAMQQEISLETR--DD--GEVMEEVEREQVTDDMEMLEIEMAKQMKD-SNEWRLDSRSMFNNKGQTR-PFVLTNERQRIKDGVFRPGLPTMTVDEYLQQEQERGNIISG-GGK----DPELDAEVIKQREWDDFRDDNPKGWGNRGGN Conco1 -ISTIFDKCEAE-YKNLVGLLEKFIKLN-LSLFSDNEFFEELSTPSIKL-LVLDSKKLFLAFLNLVDNY-D-LLDKEDKARKEIKLENRDTKIARFKREKSLEQDIKLQSK--EL--EADKDDVLRDKSFNEITSIELDVLSMMNE-DNEWRLDNLSLMDKSGKLR-PFVITGKQQELRDQVFRQSLPTMTIDDYLQKQMEMGNVLQG-GGE----RPTLDKETYKKREEDEFKDNNPRGWGNR-GN Conpu1 SVSAVYSRILLA--QAAVAAISDLRALA-LSLFSSNESLRDISTRHLPY-LAIVAQANLNAYVNNIETL-E-IVSPEDRKLYSDPAQRRELKIRQYKAEKEVKSRVTLRSRLSDD--DDEDDGAMRQHAHTNLTNLELELLRSAPS-DGSWRLD-APLLDPSGKLR-PFTIL-ERSRLQSQVFGPGLPTMSIDEYLEIERQRGNIIEG-GGQASADKLTSEKKRLKDEAWAQYTDLHPKGEGNTM-N Copci PLATLYSSALGG--PDLIKSYSDLKRIN-LAIFSPNETVEDIATRDLVY-VSLQALQYMKSFISLLETY-E-IVPETERELYSDPARLRELKINQFKKEKELKGRIELRKRQSEK--ELDTDEILREQAQTQTEMLEIEMLKMAEE-AALWRLD-APLLDSSGKLR-PFTIL-ERARLQATVFGPDLPTMTVDEYLKIEQERGNIITG-GGPASENKPTAEEKRQKDEKWARFTDANPRGAGNTM-N Croqu1 TLGQLLDRAAQV--QSKIAALSELTLCR-LAVLSPNETLEDITTSDLKC-ISVSAKTHLLDFTRRVESY-E-IVPADERSRYKNPALRREGKIAQFRLEKELKSRLEFRKRSEEI--D-EEEDGAREKAHQELSSIELDLLGTG-E-DLTWRLDRLSLIGPSGKLR-PFTILTDRIRLREEVFRPDLPTMTIDEYLDEQQAMGNFLSG-GGRAQAETETAEGLRRKAIEWDEFTDTHRKGEGNMM-N CryneH991 PLPQFYSHSLIA--QSILIALDNLYLIS-LGVFSENESVSETSNGQLLF-MSIKAEYAFQTFVELLCSY-G-VLSSQEASEYSDPAKKREAKINQYKREKELREKINVISRRKQD--VNEMAEESRELALSSMASMELDILSSAEN-DDTWRLDQLPLISTKGKLR-PFTILEQREKLKAGVFKQSLPTMTIDEYLDIEKQRGNMITG-GGQESYDKPTAEHKREKDERWAQYTDDNPKGYGNTT-N Crypa2 SLKSVFAQAEES-YRDVLQAIEDYTECQ-LRIFSPNESLEDLSTGDLPY-LLVQTRSCYERFLLALDSY-S-ILEPQYAKMLEDPAARRNSKIANYKAEQALKQKLALRKHPGED--D--DEEIVRQMAFQQLESLEAEILAQAQD-GYSDRLD-RPLLSKEGKLQ-PFTIVGNRQDLAKQVFRPGLPTMSIDEYLEEEKRRGGIIEG-GGEASWHRPEADEDTMKARAWDEFVEANPKGSGNTL-N Debha1 TVSERYRNAIGK-YQTNVDLIKEFTLIR-LDLFSDNESLNEINVSYIQF-INLIAKSKLVHFIAQLDNY-GEVLSKSQSSRVNNPALKRADKIENYKLEKELKGKLQLNDYYNDS--MFEDEEIVKASAFNNLELLELQVLSNRNDYGYTSKLESLPLISKQGKLQ-PFTITSNKQDLKLKVFGTGLPSMSVEEYLDYELANGKMMKE-EVKDE-----SDEELEK-RQWDDWKDDNPKGSGNMKAN Dekbr2 SLSKQFQVVVKP-GESTFSILKQLKDIE-LQLFSSNESLDEVTTADIKY-LAIEANQLYLQFLQKLDDY-G-LLDKKQSKIMDDPTLRRASKIANYKHEKEFQKALNLNDKEA------EDDENLRNKSFESLESNELQLLKNYFDKGFTDRLENLNVLSKNGRLR-PFTIVEKRDQLRQKVQGTGLPTMTVEDFVNHELKNGGMVAK-SNKNEANDA-QDKETYRQREFDDFKDYHTKGSGN---- Dicdi TLFESFTWGQKE-YQKQVSSITHFFTAK-QQIFSKNEELEDIRTDSLKY-LLITSKQKVLSFLQECERL-K-LMDKEDLEIVHDPVNRRNELISRNKRNREIKDKLAVKKR--DS-SEIEDEELDRQKAIGLLETIELPMLQQIEQ-----------KVSTKGSIG-NFQILDGRRIALDRVFRPSLPTMTPQEGAEWDMHHGGMVKGKGGKESEAKEK---KLREKRNWDNYKEDNPKGWGNSL-- Dmel KLTDIFLKGWN--FQNKVTAMGLFEQAQ-VSMFSANELIDEVSTESLPF-MLL-GEIYFKDHLQRCQEY-D-LKADSQAE---AFN--RNDKIAQYRRMDEYMARMR----------DAVDDEDKRV--YLDKSIIELETLGVMPN-QNQSSASSTSHHQQAAKLQ-PFIIT--RNATQKAVFGLGLPIMTVDEFYQQRVDEGIFPDEEKVAKMNQAQADPEYIDRMRRMDEYKDVVRRGDGNRH-N Enthi SLLQSFNNV--V------NALKELEQYK-TYAISKNEEYDDIATSSLGY-LMILSQSHYISFLNEMARL-RFI----NKQYITTPEQARNTRIERFKESQQAKNILKIKKKQ-----ERDDEEDERENSIDNFGYQEVTMLKEIFE-KRKEKEDQEATFAAQNQVK-EFTYKPEKLEIMKNVFNPRYGRMMTDEDWEAE-KRDEMLDP------IEEPEDDEKLKEKREWDEFKDAHPRGSGNTL-N Falba TLSSDLESSLSE-FASRLAAIEASDVLA--------EPLESWGTTDLLL-LLTACLRHLNYFVERIETLQG--VQAAGRRLTDAAEEERRRRIALYKRNKALTGRIEFPSAGAGD--DAEDESTLRSRALAHARAVELPMLTSR-------------RVAAAARLRTPVRLMHRRAALQEQVFRPGLPTMTISEYLDREAQRGGHISG-GGPEGDARAAEDAARLKAIESDKFTDYNKRGSGNTY-N Fomme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 SLRSLYEAAEEA-YRSDLAALSLYNSAG-LALFSPNEGIEDVSTTDIPY-LLLKSRAAYERFLAAVDGY-G-LVQAPYDRVLEDAAARRDGKIANYRAEKALKEKLELRRNPR-------DEELVRESALQALDSLEVDILAQAKD-DHSYRLD-QPLLSKQGKLQ-PFTLVGSRDQMSRDVFRSGLPTMSIDEYLEEERRQGNILQG-GVEE------VDRETYKQREWDEFVDHNPKGAGNTL-N Galma1 SLPALFTRILNT--QELVECLKDLRNLE-LSMFSPNETLDDIATRDLVY-LVVQVEKYLKNFIDLLEKY-D-LVPDEERSLFDDFGKRRELKINQYKKEKELKSRIEIRKRTGEE--ELDTDEILREHASSQLQTMELDLLRHAEE-DNEWKLD-IPLMDADGRLR-PFTIL-ERARLQAQVFGPGLPTMSIDEYLEIERQRGNIITG-GGPASQAAPTEETKRQKDENWARYTDENPRGAGNTM-N Ganpr1 -------------------------------LISSNELLEDIGTGDLRF-LGVKAKRHLDSFISTCKVT-G-LTSREDEQYLEDAQKRREEKLARFKREKLAKQKIKLQER--SS--DDSDDDLDRSKALDSLGLTEMGLLAKMRE-RSRGIKDGRTLLSSDGKLR-PFIITSERERLREGVFKPDLPTMSIDEYLEIERQRGNILTG-GGE----QPELDAELLKQRKFDDFKDSVRRGSGNR-HR Gloin1 -LSGEFRVGQEL-YQQDVSAISHFRKCK-LKIFSANETVEDINTSDLRF-LLVEAKLYFEQFLRNVELH-E-ILKEEDRKFIEDTAKRREEKIARYKREKETKMKLELQQTL-----EDNKEDISREKSIEQLISIELELLDQMSR-DT--------LLSKDGKLR-PFVITN-RETIREQVFRPGLPTMTIDEYLEQEAARGNIISG-GGQ----IPEIDEETLKAREWDEFKDSHPYGSGNR-MR Hisca1 TLHALFSRAKST-LSD---VIAEFEECQ-LSLFSTNESLDDITTGDLQY-LTTRSRDEYEKYIERLDQY-G-LLSLEDKKLYEDAVARRNIKISRYRDEKELKQQLELSQSQG-------DEDLTRQHTFQALDMLELSMLASSPP-GFSDRLD-IGLLSKTGVLQ-PFVLTSKRTELRNGVFRPGLPTMSIDEYLEEERKRGGIIEG-GGEQSDQPKEADEETMKARAWDEFTEDNPRGSGNTL-N Klula1 -ASQEYDKFLKE-YQEILKCLAHGLNFTKSHLFSTNETLDDVSTKSLRF-LSLKTVQLLVQFLVSLQDY-C-ILPESLSKRVDDATLKRQEKIELYRTGREMEMQIKLENKLD----D-DAEETLRLESWNQLEQIEIELLNNFDPTGYTEKLESLNLISKSGKLR-NFTLLDKKDQLKSKVFGYGGPTMTVEEFLAKEFEENRVLQG-GAEPVEE---NDLATYKARAWDDFTESNPKGSGNT-MN Lacbi2 SPSALFNRSLDT--QELLQSLNDVESLD-LSLFSPNEVFEDISTRDIIY-LFVQTEGYLRSFISLVENY-E-IIPEDERSLYSDPAKRRDLKISQYKKEKDLRAGIEIRKRGGEQ--PLDTDDVLRKEAQKQLESLELEILRNASD-GDLWKLD-SPLLDSSGKLR-TFTIL-ERSRLQAQVFGPGLPTMSIDEYLEVERQRGNIITG-GGAASRAAPTAEEKRLKDESWARYVDEHPRGAGNTM-N Lenti61 PLSSLFHRALTT--QELISALMDLRQCK-LSLFSTNEQLADIATRDLVY-ILVNVKRHLESFIHYLELY-G-IVTEEDKELYGDPAKRRELKIKQYKREKDIKARIEVRKRTDTA--EHDMEEVLREEARSQLESTELELLHNVPE-DDMWKLD-APLLDPQGKLR-PFMIL-ERARLQAQVFQADLPTMTVDQYLEIERRRGNIISG-GGPQSESKPTAEEKRQKDEAWAQYTDTHPRGAGNTM-N Malgl1 ------MMADDSGDDASV--LRLLREVA-MSIISANDLKDDISTPSLRL-FLIAAIGAARVFFTIARKH-E-ILPTSLTRLLQ-PAEKRMNKIQQYKLEKAVQAQLSYRSRKADD--DDDGTDLDRVRTANTIESAELELLSHAEP-DKTWRLDTGWLLSETGRLR-PFTITTKREQLASEVFRPSLPTMSIDEYLEEEARRGNIIQG-GGHSQSQQPTEEEARQEAIYWDSFKESHRRGEGNTM-N Mellp23 -------------------SISDLKLCR-LGILSSNETIEDMTTKDIKC-LIVLAKHHLLEFIEQIESY-E-VIQVNERSKYQNQAIRREGKIIQYKLEKELQFKLNYKTRKETL--DNEEEEGEREKSYQEINSIELDLLGTSAE-DLSWKLDQLSLIGPTGKLR-PFTILTDRIRLRSEVFRPDLPTMTIDEYLDEQESMGNFLKG-GGPAQAEEETAEGLRKKAIEWDEFTDTHRKGEGNMM-N Mnele --------------------------------------------------MTVAAKEYYKDFHHLCQLY-D-L----------VNNSNRMEKIQKYQDKKNLETKLE----------EMEEEEVQRERVEDEIYNIELPMLEHM----RGGQVKQ----RPIIKMK-PFILV--KSELQKQVFGAGLPTMTLDEFYDQEMK--RIVEEQERQKNQPKP-TEESLAKARAWDDWKDTHRRGEGNRH-N Monbr SIAQLLSEAEA--SHEAVRAVRQLQSLH-ANLFSSNEAYDECSNDTLRC-LSVQTLQYYQKFLADLNQL-Q--FPFASAEMLEGIRRSREVKIEHLKALRQTEGTVQLRAA-----IDRADEDLARQKACEAIDMLELKMLEDIEE-----------------A---PLVLTVDRANFKLLTRGYGAPTMSLEEVADREVRE-------ALERQAQEKLDYVDAMQGRAESDYWDNHKRGEGNRY-N Morel2 SLAQVFQKAEVE-YQSKVQSIRGFELSQ-LSLFSENEFMEDISTKDLRF-LLTSGKEHLDHFLLQCETH-D-ILTPSDKKYLEDAATRRGEKIARFKREKEMRNQIEFHKI--EG--ELSLEDQYRDQTMEQLVSIEIPMLQQMDD-ARDGKVDSSTLMDPQGRLR-PFMITNKRAEMMKGVFRPGLPTMSIEEYLDQEMERGNFLSG-GTE----EPKINAETIKARNWDDFKDDNPKGWGNK-GG Mucci2 -----------A-YQAQVKGFQMLSRAK-LAIFSDNELLDDINTNDLKF-LLIKARDYLQKFLSTCQDH-A-LVQKQDLSLMEAASQQRDQKIARFKRERAVKQHIALRQQ--ED--E-DVDDMEREKALENWHAIEMVMVKEMVD-SREAPQTSRAMLSKEGRLQ-PFVIMNKREQLKSQVFGYGLPTMTIDEYLDQEMERGNIIQG-GGE----EPEHDAETMKKREWDEFVEANPRGAGNR-GN Mydma KLTELFTIGWK--LQSKMECIKCLVRCL-LGIFSSNETIDEVSTENVKF-FLLSSKVYFQDFLKRCQNY-G-VQTDVEEQ---NQKQTREEKIQRYKENKLV-QSLL----------EKSDDQV-RKKAIENIPMIEMLILKHM----KQGKVEPTP--RKERMMK-PILIT--RDMIKNSVLGYGLPEMTIEECIEKEIKEGKILLEYNKSKLNRP--DEEELAHKRAWDEWKDTHRRGEGNKD-R Neucr2 SLKATFAAAEEADYADTVAAIKLYQSCL-LSLFSSNEGLEDLNTNDLPY-LLVQAREAYERYLHLLDSYEG-LLNPTYKKLLEDPNARRNAKIANFKAEKELRQKLALRQRPEEL--DDDDEELVRSLTFQALESLELEVLNMADR-DYSDRLD-MPILSKEGRLR-PFTLTGTRQEIAKGVFRPGLPTMSIDEYLEEERRRGGIIEG-GGEASWKAGELDAETMKARAWDEFVEANPKGSGNTL-N Orpsp11 SLKQEFEIGQKN-LQKQVDAIRHFTRAQ-LSIFSINETVEDINTSDLKF-LLITSKKNFNEYLSNCELY-E-LFSQKDKEYLENAARNREEKIARYKREKETKNKIELTKQ--------EDEEISRNQTIQNLEMIEMEMVKMMDR-NNFAPIPTS-LLSQKGQLR-PFVIVDHKERL-NQVFRPSLPTMTIDEFLENERKRGNILSG-G------------------------------------- Pench1 SLRSLFASAKES-YRDEIATIAKFQECM-LSLFSSNELLEDISTSDIQY-MTLRALEQYEKYLMRLDEY-L-LLSGGDKKLFEDAAARREIKVTRFREEKELKQKLEFARNEA-------DDDDTRSQTFQALDLLELSILSAMGL-NYSEKLD-PSILNSKGKMQ-PFTLLGRRAEMQQGVFRPGLPTMTIEEYLDEEHRRGNVIEG-GGEKSGIKPLADQETMKARYWDEYTEANPKGAGNTL-N Phybl2 -LGQLFSRSQAA-YQQLVEAIEQLQQAR-LAIFSSNEFLDDINANDLRF-LLIDAKEAFHRFLSTCQEH-Q-LIQKQDLADLEPAAQQRNEKIARYRREKAAREKLVLRDR--KD--A-EDDDVEREKSLEHLHAIEMMMVKEMED-DRV-PTGLNSLLSKEGRLQ-PFVITNKRQQLTDQVFRPGLPTMTIDEYLQQEMEQGNIISG-GGK----EPEVDAETIKQRNWDEFKEANPKGWGNR-GN Picst3 -----------K-FQSKLSIIHQFRVIQ-LALFSDNETIEEVNTKHLPF-LLVTAKTSLISFLVQAQQY-G-ALSKLQSDQINNPAERRQIKIDNHRLEKQLNEKLLLNEFYDDNGIEFGDDDTVRANSFSLLESIELKVLQNRNDYGFTTRLESLPLISKQGKLQ-PFTITSSRQQMRDKVFGTGLPSMTVEEYLDYELANGKMMKE-EVKDKN----SDEELEK-RRWDDWKDDNPKGSGNMKAN Plicr1 PLPTLFSRALAT--QELIGALADLRRLS-LSLFSPNETLEDIATRDLVF-LFVEAQTYLRTFLSNLENY-N-IVPEEERQLHEDPAMRRETKIKQYKKEKELRTRIEVRKRRRDD--EDDTDEILREQAHAQLESMETQILLNAEE-EDTWRLD-SPLLDPAGKLR-PFTIL-DRARLQSQVFGPGLPTMSVDEYLEIERQRGNIITG-GGAASAAAPTEEQKRLKDENWARYTDENPRGAGNTM-N Polpo TLFQLFTYGQKD-YQSSVSAILYLMKSK-QSLFSKNEELDDIRTDLLKY-LLVNAKNKAIQFLQRIETL-G-IISQDDQQIVTSQANRRNELVSRGKREKEIKQKLAIKKR--DS-LDEEDEEVEREKSVANLEMLEMTMLEEIAA-----------P-PPKPSIG-NFKILDGRQIMLDKVFRPSLPTISPEEAAAWEMHNGGMVKGKGGKESEKKGSNHDKLREKRDWDDWKDDNPRGWGNIK-- Pucgr2 TLGQLLDRATSV--QSKIAALADLSLSR-LAILSPNETLEDINTNDLKC-LSVQAKDHFKSFSRQIEAY-E-IIPREQIERFKSASMRRESKINQYKLEKQLKQQLDLRERKRSD--DDDNESESRSKAHQELDSIELEILGQA-D-DLSWRVERLSLVSPSGKLR-PFTILTNRIKLRAEVFRPDLPTMTIDDYLDEQRAMGNFLSG-GGPDQASQETAEELRKKAVEWNEFTDSHRKGEGNMM-N Punst1 NLPALFRRALKT--QELVSARRDLQEVA-LSLFSPNESVEDVSTRDLVY-LFTASRGYLQTFVDRLLSY-G-VIPEAEQKLYGDATRRREMKIKQYKAEKELRAQIEIRKRRRPD--EDGTDDVLRQQAQSQLASLELALLRSADD-AKDWRLD-IPLLDPNGKMR-PFTIL-DRAEVQSQVFRPDLPTMSIDEYLEIERQRGNIITG-GGPVSMEQPTEEEKRQKDENWARYTDANPRGAGNSM-N Rhior3 -LGQLFSFGQNE-YQQKVQGIAYLNQAK-LHLFSDNEIIDDINTNDLKF-ILIQAKTFIQNFLTTCQTH-E-LVNKEDITVMQA--QQREQKIARYKREKELKQTIQLRQQ--DD--E-DVDEMERDKALENWNAIEMVMLKEMTL-AAVDQVNSRALLNKEGRLQ-PFVITGKREQLKNQVFGPGLPTMTIDQYLEQEMERGNIIQG-GGE----PPELDAETMKKREWDEFVEANPRGAGNR-GN Rhoto1 SLGQLLSRSLRV--QTLIQTLSDLTLCH-LGILSPNETVDDISTRNLRC-VLVRAKGYLRAFVEDVEKY-E-VVGEERRGVLRDPSRRRAGKIAQFKMEKEIKTTLELRTRRRSS--DDETESVARPRSHAELGSIEIEIVDHG-E-ESRWRLDRLPVLSPDGKLR-PFTILSTRLRLQSEIFRPSLPTMTIDEFLEQEQERGNVLQG-GGP-KTSDEVEEAGLRKKREWDDYTDQHRKGEGNMM-N Rozal11 -LNTLFHNSHNE-YQIQLKLLNILVLIR-EHLISKNEEIEDINTETLKY-LLIDALAHSKRFLEVCVCI-K-LLKDEEYDDLSSPEKQRESKIAKYKQEKHLASLLELKER--------DDEEIQREKIFELIKIIELQLIKSF-------------VRSEPSQSK-PFVLLSKREKMRNQVFQPGLPTMTIDEYLEIERSRGNIITG-GGQ----TPQEDSQIYKIRQMDDFKDANPRGWGNT-YN Sacce1 SVTEQFNDIISE-YQGLLSTIKKLLNLDRLALFSTNETIDDVSTASIKF-LAVKSVESFINFLTLLQDY-K-LLDPLVGEKLGGAQLKRKEKIELFQRNKEISTKLHLELELK----DEDHDELLREDTINNIEQNECEMLSNFDSTGFTDKLENINLIDKKGQLR-NFTLVDKRQQLQQKVRGYGGPTMSVEEFLDKEFEEGRVLQG-GEEPEQ----QDRETYKAREWDEFKESHAKGSGNT-MN Salro NLPALFAKAMS--PQKRLEGLASVKRAH-LNVFSDNEEHTEHSTLSLRY-LAIRARELYQQFIRNLRDM-E--FPFAAPKVVDGNRRERDTKIAHLKAMKAAESTLQIEEV-----VKSKDDEMHREKACDQVENVELSMLEHVE------------QLRDEAK---PLVLTINRANFKLLTRGYGAPTMTMEEVAQIEMQQ-------AMEAQRRQQQSVAETYKLRAQDEWNDDHRRGEGNRY-N Schco3 PLSGVFSKALST--QDLITSLADLQNVD-LSLFSPNETLEDITTPDLVY-LFVQAESKLKTFIFTLEHY-N-IVPEDERKLHEDPARRRETKIKQFQKEKELKGRVELRKRRNDQ--EEDTDEILREKAQAELGSIELDLLKSAEQ-DAMWRID-VPLLDPDGKLR-PFTIL-DRARLQNQVFGPGLPTMTVDEYLQIEKERGKFISG-GGKASESALTAEEKRLKDENWAQYTDTHARGAGNTM-N Schpo1 SLRELWEETE-T------EIVEGYEKCQ-LRIFSSNEEVDEIKTSELRY-LMIYAKTHYETFLSICDDY-G-LKPMQDEK---TEADTRTLKIARYRMRQNLEKELKLSKDSE-------NEEQERKDTLDSLPHIEIDLLKRAKE-GSSWRLD---ILDKNNRLQ-PFTIVSDRNETRKNVFGFGLPTMTVDEYLDEEMKRGNIIS------QKDNPPLDAKTMKDRYWDEFKEANPRGSGNTMVN Sorma SLKATFAAAEESDYADTLAAIKLYQSCI-LSLFSSNEGLEDLNTNDLPY-LLVQAREAYERYLHLLDSYEG-LLNPTYKKRLEDPNARRNAKIANFKAEKELRQKLALRQRPEEL--DDDDEEVVRSLTFQALESLEMEVLNMAPR-DYSDRLD-MPILSKEGRLR-PFTLTGTRQEIAKGVFRPSLPTMSIDEYLEEERRRGGIIEG-GGEASWKAGELDAETMKARAWDEFVEANPKGAGNTL-N Sphar --------------------------------------------------------MYLQAHLETLTQH---I-------------------------------------------TSTDDSQLSRDRACDDLAMLEKNMLVHMED-----------EPPKNNKFK-PFVLT--KEMVNKGIFGNGQPTMTIEEAAEREHNLG--MHG--------------------------------------- Spipu1 PLRKEFQRGQAA-FQEDVEGINSLLRCT-LGVFSSNELLEDINTADLRY-LLVTAQHHYERFLAACEQH-E-ILRADDKKFLEDPERKRMEKIARYKREKATKEKLTLHEQ--PN--EDEDEELDRERTAENLKLIERKLLEMAIE-GTP---PPRMLLASDGKLR-PFVITSKREALRQQVFRPGLPTMTVEEYIDKEIERGNFLSG-GGK----EPELDAETYKARQWDEFKDDTPRGWGNR-YN Sporo1 TLGQLLTRAINI--QQLLATLADLNLAH-LGILSPNETLEDINTNDLRC-LLTRAAEHFRKYSTLVEQY-E-IVPQDQRAAYQDSARRRAGKIAQFKREKEIKATLELRKRRGED--DDEADDVARPRAHAELSSLELELLEHG-D-DLTWRLDKVSLLSPSGKLR-PFTILQTRLRLQSEVFQSSLPTMTIDEYLDQQQEMGNVLQG-GGP-STSEEVEERGLRKVREFDDYRDTHRKGEGNMH-N Stehi1 TLSSLFHRALLT--QELVSALKDLKDVE-LALFSANETLEDISTRNLVY-LLVDAERDYRLFLSDLELY-E-VIPEDERELYADAAKRRETKIKQYKQEKEIRAKIEIRKRRNED--DKDTDDILREQAHSQLESIELELLRNANE-VD-WKLD-RPILDPQGKLR-PFTIL-DRARLQSQVFQADLPTMTIDDYLEEEQRRGNIITG-GGAASAAKPTEEEQRQKDENWARYTDENPRGAGNTM-N Tapde11 DLRKQFS----T-NDQLIRAVKAWLTTK-LAMFSENETLDDLITTEIRY-ISARASQSYKEFLSMCKSY-T-MVSSADVSSVTSSAELRQQKIQRFKRDKELEASIALSGNTR-------DEDEARSKVVEEIKFIELTILASEED-SSTWRLD---VLSPNGKLT-PFVITSQRQTASAAIFGSDLPTMTIDEYLDNERKQGGMLSS-TNPQH--TPDQERERQKAIYWDSFKEENPKGIGNTM-N Thetr SLHGRYRELVA--VRTQIATLGALDQLA-AGVFSRNEELEDVRSQDLPL-LSAAAWIKMNEFLALAEHY-G-IVTADQIDAAASHDDRRTIKIARAREASALKRRAGLETAVA----DADLEEEYRETALDEALMLEIGALKQM--------------------MS-KVTISVERMRVFSNP----KPTMSIEEWAEAQMAAGKLPSPEDVQVMMAEQASDAAVYAAREWDDFKDANPRGSGNMMAN Treme1 PLPAFYAQVLHT--QEILTALDNLHLIS-LGVFSDNESLDEVGDGELVF-MTVRSDTAINAFLHLLNSY-K-VLSPDEEAE-SDPARRREAKIRAYKREKELREFISSVPDQPTS--VNG--PDTRRLALALLASTELELLVSAEI-DNTWKLDRTPLISGGGRLR-PFTILSDRERLRGEVFRESLPSMTIDEYLEEEKRRGNIITG-GGQASYDAPTEEQKRLKEENWAQYTEVNPRGAGNRM-N Trire2 SLRALFEAAEAK-YAEDLAALKLYAQAA-LSLFSANEGVEDIATSSLPY-LLVQARSAYERFLSLADGY-G-LLTAPYDKLLEDMAAKREGKIANFKAEKALKDKMALRRNPR-------DEELVRESAFQALDSLEVPLLRSAPA-DTSFRLD-QPLLSTKGKLQ-PFTLIGSRADLAKGVFRPGLPTMSIEEYLEEEKRRGGIIEG-GGTEP----PVDRETYKARAWDDFTDDNRKGSGNTL-N Umbra1 -LSELFNRGQGQ-FQSQVQGIAYLEKAR-LGIFSENEILEDINVNDLRF-LLVLAKKYLVEFVHTCEVH-Q-VISPVDAKLFKNVATSREQKIDRYKREKETEAKIKLQEI--SG--EGDVEDIERDKSLEHLQSIEYVMVLEMQR-SPQPRIDPRNLLSKTGTLR-PFIITSKRQELKDQVFRPGLPTMTIDEYLQQEEERGNHIKG-GGK---DQPKLDAETMKARDWDVYKEDNPKGWGNR-GN Ustma22 LIAAVFLRASDT--SASVTTLSLLARAS-IGVISANDELRDISTSSLRT-LFLLSQQAAARFLNRTWAL-G-VAPPNTKQLLGTPPHAREVKIAVFKLERALKSNLEYQAKQKDD--EDDEEESERSRTAQCIASAELELLRSMES-EQ-WRLDRS-LMTPQGKLR-PFTIT--REEVASNVFQPSLPTMSIDEYLEEEQRRGNIIQG-GGQASYDAPTEEEQRQIDLHWDQFTEHNKRGAGNTM-N Walse1 --------------------MLEYKELE-EGVFST------------------------------------------------------------------------FNK---NE--EEDDDEVVRDQATKQLQSSELELLKNIPT-DRTWKLD-TPLLDKNGKMR-PFTIMTTRQQMSEGVFQHSLPTMTIDEYLQGEADRGNIIEG-GGPASENQPTQEKQRVDGENWARYTEEVEKGSGNKMSN Zygro1 -LSQEYESLLRE-YQSLVKTIEKLLSLGDLALFSSNETVDDISTKSLKL-LSIKTVQLFMQFLTTLQDY-E-ILDPFLSKKIDGAQKRRQQKIEMFRQSKTINEKLEIESKYK----EISDDEQMRKQAFNEMEQIELELLRNFDSSGYTEKLELLNLLSKQGKLR-NFTLVDKRTQLQNKVRGYGGPTMSVEELLQKEFEENRVLQG-GEEATNENV-QDQETYKARQWDEFKESVARGSGNT-MN [Cluster2158.fasta_al_trimmed; alignment length = 237] Allma1 SLTGDRVLAVLDLLDGLKERG-FNVQVESVTSADHLLLLT---TKVIHF--VNAGGNALIATTKLAGEFGIDF--LTDY-RGIGNPYLLPVLDANPTSVGLVSAMQAANN-ARVALVGSLDVLADENAAFATELLQWTFQEKAVVRAYRIKDEIFNITLQEDTLQFSATMLHPYVRFVHLPDVYGVYTFAATCNEPGLVSIRPYRHNEYPR--YLPVAWPYYVGAYSHMAAFVVFAA Ashgo11 SVHGMKTLLIYDFLGMLRERQ-YQVEEVSVDGYDNLILFPIK-SRLLQF--FEEGGSVLAVTSPYLEQMKIHVYKLVDY-SGSSDGLVIPVLPAPRTSLSLVASVQNLNN-ARTSWVGSDSFFNDGNGAFVEELIKWTFGEKAVIKSYKIKDNIYEIGFSEDDIQFELRMLDPYYRNFALPDHHGVYTFVTQYMNSGVKPIRHLANDEYPRSYEITNSWVFLCSISAVIALFVAFVA Aspfu1 SSSGSRLLVVLELWADLEARG-YNLDFESPKNYDHMLLLPPK-SKIIDF--MNKDGNVLLALSGLLLELDLHLSVTVDP-RAVPNPLIAPILRAPATAYSLVSAMQARNS-ARFTLLGSVESLQDQNQEFAKQLTAWTFKETGVLKVYRIKNETFSIELSEDAVQLEFTMLSPFHRRFTTPDQHGIFSFRVNYKRPFEVTVRHFAHNEYPRSWKISGGWVWIAGLWSVIAGFLVFVV Aurde31 SSTGSSVLVVLEFFDGLKASG-YELTFRAPKDFSHVILFTPT-TKLVQL--LNLRTNLLITTSPLALEFGLTTTPLISY-SGTANPMQVPILRAPPESFAVVVGFQARNG-ARVTWVGGVSLFSDENKEFSQEVVKWTFQENLVYRIYTINDKIYELTVSKTDMQLEFTMLDPHLRSFRAPDRHGVFKFVVDWKRRTTVPVVPPRHDGYPR--FLSAAWPYYIGAISTSVGFVLFCA Batde5 PVGDSKTLVLLDFLDSLTARG-HRLFVHTVAQFSHVVILASK-VSLIDY--VNAGGNVLLAASSFAYEFSVDFTSVFDF-QGVGNILTFPILTASHSAYSLASAFQARNN-ARVVFVGSTSLFSNKNAAFSADISKWVFQEKSVVQIYRIKDEMYSATIKVNDIQFEAVMLDPYIRRFTLPDQYGVFSFKLNYQRHGTVQVRPFRHNQFPR--FLVVAYPYYANIFSLMVAFFLFSA Botbo1 SSAGSSVLVVLEFFNSLEKRG-YELTFRAPLDFSHVIFFTPT-TKLVSLATANQNINILIALSPLASEFSLSLTPLISL-SGVSNPLLVPILNAPAESFAVVTGFQTKNG-ARVMWVGGVSVFSNENAQFAKDITAWTFQETMVLRIYTTNEHLYIIQLSAKDLQLEFTMLDPHIRTFRAPDRHGVYKFVVDYKRKGQVSIVPPRHDGYPR--FLSAAWPYYAGAISTSAGFILFCA Botci1 SAGGNKLLVVLEYFGDLEARG-YELTYESPKNFDHLLVLPSK-SKLLEF--INKGGNILLTLSSLLLELDIHLSLVVDP-RGVGSPLLTPLLRAPRTAYSLITTMQARNS-ARFTVIGSSEILEDTNQEFSKEVTGWTFKEIGVLKVYRIKNDV----------------------------------------------------------------------------------- Caeel QSLADRVLVLGEFLNSVKERG-HELTVRAADDFDHLFILAPG-VQISKF--VDAGGNVLVAAGSIAAEHGFEFTSVIDF-KGIGNNLALSIVRASGTAYSLVGGLQSRNN-ARIVFTGSSELFSNTNADFATAITRWVMKESGVLRVYFITEDVYTIEIEEKDVQLEFVRIDPFVRAFKLPDVLGVFKFLVDYRRVGQVSVRPLWHTQYER--FIRSAYPYYASSFSMMAGLVLFSI Canalb1 RFDVEHALVLYDFIEYLSDK--FDVKISDYNSYEHLVLFPSS-KKLLRF--INENSNIFVVGGSFLNELGVFPYKYIDY-DGNANELIFPIVRSSATGYTLAVGFEALNN-ARLVWVGSNSLLAEP------QLYKWCFQQQGKLKLYRIKDQAYTIGVSEDQLQLSFKMLDPYQRNFTVPDHHGMFTFELDYKRPGVVTVRHFANDEFKRSWDISNSWLYVASAVFVIIAWFVFVV Cangl SINGGRTLVVYDYLDSLKGHQ-LTVDVIEISDYDHLIVFPAT-TKLLNF--YENGGNIMTLYSPFWAQLGVHLYTTVDFGESTTNELVIPVIPAGRKSYVSVVGHQNYKN-ARSLWIGSSDAFLNENAKFLNEITRWVFGEKAVIKTYKVTDEIYEISFSEEDIQFELRQVDPYYRVFKLPDRHGMFTFLTDYKRPGVRAIRHLANDEYPRSWTISNSWVYLSAIYGTMLVWIAFVV Capow PRVPGKTLVLLEFFRQLQEQD-FTLSFALADEYDNLIIFAPS-AEILDF--VDHGGNVIVAGSSFGSECGFEFAAVIDF-RGVGNPLTIRVLSAESTAYTLVGALQARNN-ARVLFSGSLDLFSDENRDFAISAALWTFKRSGILRVYTVFDQIYSLRVEENDMQLEFVMLNPYLRSFQAPDVYGVFQFRVDYKRTGQIPVRPLQNTQYER--FIFSAFPYYASAFSMMGGLFVFSL Catan2 SLTGDRVLAVLELFKSLADRG-FQITFKD-PSHDHALLLAP--TKLVSF--MRAGGNLLVALSAFVYELGIDVSNVRDY-KGIAHNIVFPILSASPTVTGLVSGVQGTNG-ARAVVVGSVDMLTDENKAFATELLKWALHEKSVVRIYRIKDTLVNVTLQESPIYFSAKMLDPYIRSTTLPDTYGVFTLAIDHVRVGLVSIRPFRHNEYPR--WLPVAMPYYVASVSQMFASVVLVG Cioin SKQNKKTLVLYDFFKSLSDRG-FDLTFKSADDYENLIIFSPS-VEITDF--VDGGGNVLVAADSLASECGVEFTKVIDF-NGIGNPLVLPIMKGSATCYSLVAGLQARNN-ARLVFAGSLQMFSDDNADFVITLSKWVFSESGVLRVYTITDMVFSIVIEEDDVQMEFVRIDPFVRDFKLPDVYGVFQFKIDYSRLGQVSVRPLQHTQYER--FISSAYPYYASAFSMMLGVVIFSV CocheC53 SFTGSRLLVVLEFLEDLTSRG-FTTTVGSPKDYDHVLLLPGK-SKFLEF--MKNNGNVLVALSSMLLEVDISVALVVDP-RAVGSPLTSPILRAPSTAYSLVSAMQANNA-ARLVVVGSAEMLQNKNREFAQKVSAWAFKETGVLKVYRIKTDVFQVEISEDNVQLEFSMLSPFHRGFKTPDQHGIFNFRVNYRRPFQVTVRHFAHDEYPRSYEISGAWVWIGGIWVTVLGWLAFVA Coere1 SVTGDRLLVLVPFLDSLKRRG-FEVSIRDAANYDHVALLAPA-AKFIHF--VNTGGNMIVAASALAAQFGVEFTAVIDF-EGIAIPLLAPLLTGSRSTYSLVSIFQSRSN-ARVVFSGSSALFSDANGLFINDISQWAFQEKSVLREYRVSNVIYEIDLSVDDVQFEATMLDPYLRDIKLPDRYGTFTFSVNYKRAGTVAIWPLRHDEYPR--FLSAAYPYYAGSFVMVAGFLALCA Conco1 SLTGNKVLFLQDFFNDLKERG-YEVENKKASDYDHIILFSPK-TKFVEF--VNKGGNLVIAASSLGSQFHVTFTSVIDF-NGIANPMTFPILSAEWTAISLVSGFQALNN-ARVVISGSINLFSDENRVLTQELTKWAFQEKSVLRIYRVKDNIYHINLSQDQVQLEIVMLDPYIRDLQLPDRYGVFTFKVDYRRPGVVPIRPLRHNEYPR--FLSAAYPYYTGAISMSVGFLVFCL Conpu1 SSTGDSVLVVLDFFSRLEQRG-YQLTFRAPKDFSHIILFTPE-TKLVSA--LEQGTNLLIALSDLATEFSLILTPVISY-RGVSSPYLVPLLRAPAESFALVTGFQTNVG-SRAVFTGSVDLFSNENNRWAQDVAGWLFQETLTLRIYTINDDIYEIQISKPDLQLEFTMLDPHVRAFRAPDRHGVFKFLVNWRRTGTVPVVPPRHDGYPR--FLSAAWPYYAGAASTSLGFVLFCA Copci SSTGDSVLVVVDFFDDLKDRG-YDLTYRSPKAFAHVIVLSA--AKVVEL--LNQKTNVLVALSPLASEFSLILSPLISF-SGVPNPFIVPILKAPAESFAVVTGFQTANG-GRITWLGGADMLTDENADFAREVTAWTFQESLVLRIYTINDNIFAAYISKKDIQLEFTMLDPFIRTFRAPDRHGVYKFIVDYKRKGTVPVVPPRHDGYPR--FLSAAWPYYIGAISTSVAFFLFSA Croqu1 LISADKVLIITEFWSSIQSQG-HDLSFRSSKEFQHLIIFAPT-TKLVQF--LEDGGNIILGLSTFGREFDLDFTSVIDF-RGIGNPLIINILRSSPLSYSLITGFQTRHS-SRIIFIGSIEFFSNDNAKVSQDLIAWAFKQTGVLRIYKINDEIYKVDIQTKDLQIEFTMLDPHLRVFRIPDRHGVFTFKLDYRRRNQVMVTPPEHDQHPR--FLVDAYPYYLGTTNVLLAFVIFCV CryneH991 SATGDRVLVVLEFWDSLKQRG-FELTFKEPKSYDHLIMFAPT-AKILDS--QFKGLNALYILSPHLREYDLEFLVLIDP-SGTVNPYLIDVLHAPKKSYILVSALQTRDN-ARAGFVGSGEVFSDKNAAFVTDFTKWVFQETGVVKVYTKKDDIYSLTLAQDDIQMDFTMLDPHIRRFIAPDRHGVFKFVVEYWRPGTASVVPLRHDEYPR--FITGAWPYYIAAISTSVTFLAFVA Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 EQGVSQALVVYDLVSDLKEKHGFELTLQSYSDYDHLILLPSS-KKLVEF--INREGNIFVVGNDFLNEMGIYPFKYVDY-KGTGNENIFPIVRSSKTGFTLAVGFQGLNN-ARLTWVGSESLIND-------DLLKWTFQERNVLKLYRIKDQVYTIGVSEDTLQLAFKMLDPYQRNFTIPDQHGIFTFELDYKRSGVVTVRHLANDEYKRSWDIPNSWLYVASAALVVLGWFLFVV Dekbr2 --------------------------------------MPSK-SRLEEF--SRKGGNMLLLTSGFLNQLGIYPYRLVDYENGSANEFIIPVLRAKETSITLMLAHQARNN-ARVFWAGSDTFLADSD--LAHGIWRWVSRVNGVLKSYKVKDFCFETAFSKTDAQLEFIMLDPYYRTFQIPDHHGMFTFKVDYSRPGVVPVRHLANDEYPRSWQITNSWVYVASFFSVVVAWSVFVF Dicdi DIGGKRTLVVLDFFKNLENKG-YKLQFEQSNTFDNLILFSPT-SEVTRF--IDGGNNVLFAGSNIAAECGMEITLIFDF-KGIGNPLNYAILTGSSTAFSLVSSLQARNN-ARVTFSGSLDLFSDKNKEFVERLVSWTFQERGILRAFTIKDEVYSLKVEEGSLQLEVIMLDPYIRHFKLPDVYGVFTFEASIHKSGRKPILPFRHDSYER--FIPAAFPYYATCFSMLIGTFIFSI Dmel LETDANTLVLLDFFKSLQDRG-FKLTYKLADDYKNVIIFAPS-VELAQF--VDDGGNVLVAGSEFASECGFELAAVIDY-RGTGNPLVLKLLTAESTAYSLIAALQARNN-ARVVFSGSLLFFSDENRDVAESISKWVFGETGRLRVYTITDPVYTIGIEESDIQLEFVRIDPFVRKFKIPDVYGVYQFKVDYNRVGQVSVRPLEHTQYER--FIPSAFPYYTSAFSMMIGVFVFSF Enthi ---ANKTLVILEFIELLKKNG-DEVEI--INKYSNVILLTPHYTFFIQF--IDNGGNMVITVGKLLYSLDMEVSNVVDF-SGIGSPFTSSLLKAQNSASTLVASLQARNN-ARIIVSGSSLLFSNINKKFTENIIDWVLQRRCVIRMLVINDTIVNVELEQDDLQIEFKLLDPVIVIVQTPDKFGVYTMIINYRRPFTIPLRTFRLTQVDR--FLTGAYPFYAACASMAVGFIVFSF Falba RPSGDRTLVLLQFLAMLQDIG-LQTSVAFGDSFGNLIFVGTD---LIKF--MERGGNVLAFFGPFGYQIGFEFFRALDY-SGTASLQVVSFLRGNPTTFVLVAGMQTRKN-TRALLAGSTSMISNHNRAFARNVLRWGVNRAGLLRVYTIWDRIFRAEIQQ----VEVKMLEPFLRTFSLPNAYGVFTFSLSLMSPGVVAIRPLRYSQYER--FLPSGHFSYAAIWVMAAATVLVTL Fomme1 SAAGDSVLVLLEFFAGLEDRG-FKLTFRDPKAFNHVIFFTPT-TKIVSL--ISSGVNVLFTLSPLASEFSLIPTPLISF-DGAPNPLVVPILRAPPESFALVTGFQTRTGNGRAVFAGGISLFSNTNARFVQDIAKWVFQETNVLRIYTVNDQVYTVRVSRNDLQLEFTMLDPHIRIFRAPDRHGVFKFVLDYKRQGTVPVVPPRHDGYPR--FLSAAWPYYAGAISTSTGFVLFTI Fusgr1 STAGNRMLVVTDFFRDLSERG-YQITFESPKTYDHLVFLPTK-IKILEF--VTAGGNLLVTMSSALMELEIMVGKVVDP-HALG-ELITPVLRAPPTAYILVTVFQARNS-ARITVIGSAEMLQDKNREFVTNVAAWTFQELGVLRVYRVKNDVYNMSLSEDEIQLEFTMLSPFWRNFTLPDQHGIFNFKVNYKRAFTVSVRHLAHDEYDRSYSINGAWTGIAGTWATIIGFISFCF Galma1 SSSGNSVLVVVEFFDGLKDEG-YELTFRSPKDFAHVIVLASE-TKLISL--LNLKTNLILALSTLAPEFSLILTPLLSF-SGVPNPFLVPILHAPPESFAVVTGFQTLNG-ARITWLGGVDVLTDENAQFARDIAAWTFQESLVLRIYTTNDQLYNAYVSKRDLQLEFTMLDPHIRTFRAPDRHGVFKFIIDYKRKGTAPVVPPRHDGYPR--FLSAAWPYYAGAISTSVGFFLFSA Ganpr1 SASGSRVLVLLDFFSSLSERG-FDVYFKEASDYDHAILFSQK-SSLVEF--VKLEGNVLAAVGRFAYEFNVGVTAVIDY-DGVANPLLLKLLVGSATTYTLAGAAQTRSN-ARVTFVGSQKLFSDRNAAFAADISKWTFQERGVLKIYRVKDHIYQLDISEPDVQVEAVMIDPYIRKFQLPDQYGVFTFKVDYRRPGTLPVQQFRHNDYER--FLVVASPYYAAALSTATASFLFMI Gloin1 STTGPRVLVLLDFFGSLEGRD-YIITYKTTKDYDHFINFAQK-KVLINF--MNDGGNLLLVISSFARELDIEITSVIDF-RGIGVPLLTRILWANDTAYSLISALQARNN-ARVTLVGSLEFFSDRNEAFVNDLAKWTFQEKGVLRVYRIKDNFYTIDISENDVQLELIMLDPYIRHVQLPDVYGVFTLKVNYKRPGTITIRHFRHNEYPR--FISAAYPYYTGAASMGIGFLLFCF Hisca1 SSAGNRLLAILDFWKDLEGRG-YSISFQSPKDYDHIALFPLK-SKLLDF--INSEGNILLALSGVLLELEISLALVVDP-KAAGSSLLVPILRAPETAYSLVSAMQARNS-ARFTVVGSAESLKDKNREFAKQISAWTFKETGVIKVYRIKNDVFNIELSEDAVQLEFTMLSPFHRSFTLPDQHGIFSFRVNYKRPFEVTVRHFAHDEWPRSWKITGGWVWIAGLWSVIGGFLIFVA Klula1 SVHGLKTLVIYDFLDSLKQRS-YDIQLASVNEYDNLIIFPLK-TRLVQF--HTEGGDIMAITSPFLNELGIYPFLLKNY-EGSAGEYIVEILRAPRESVCLIAGFQTLNS-ARTTWIGSSQFFDDENGPFIEELTKWTFREKSVIKSYKIKDEIYEIGLSVNDVQFELRLVDPYYRNFKLPDHHGMFTFLTDYKRSGTKAIRHLANDEYARSYEITNSWVYLTAIGSVIISFILFVA Lacbi2 SSAGDSILVVVEFFDGLKEQG-YELTFRQPKEFSHVILFASE-TKLVHL--LSLNTNIIVALSTLATEFSLILTPLVSF-SGVPNPLLVSILRAPPQSFALVTGFQTLTG-SRITWVGGVSLFNDENAQFAREVATWTFQESQVLRIYTNNDNIYTAYISKTDLQLEFTMLDPFIRTFRAPDRHGVFKFVIDYKRKGTVAVVPPRHDGYPR--FLSAAWPYYAGAISTSIGFFLFSA Lenti61 SSTGDSVLILLDFFGDLENKG-YQLTFRSPKDFAHVVVFAPN-TKLVSL--LSKNTNLLLALSPLASEFSLILTPLISF-SGVPNPMLVPLLKAPTHAFALVTGFQALTN-ARATWVGGVEMFSDENRQFASDVAAWTFQENHVLRIYTINDRVYTAYISKKDLQLEFTMLDPHIRTFRVPDRHGVFKFVIDYKRKGVVPVVPPRHDEYPR--FLSAAWPYYAGAFSTSAAFVLFVA Malgl1 SATGSRVLAVVGFLGSLKERG-YTT-----TSFDHAVILAPN-MKLIDF--LRDGGNLMVGLSPFAREFGLEFTMLVDY-RGIASPLAFPLLLPPATSYQLASAIQLRDNSARVMFVGSVEIMQNEQRAVVDDLILWTFQEHGVLRVYRIKDTVYVLEVQQLDLQLSAIMLDPYVTILGLPDRHGVFTLRVNWKRHGVIPVRPFNHNEYPR--MLSSSWPYVAGALSTMLGFSTFVA Mellp23 LVSADNILVVIEFWSSIQSQG-HQLSFRAAKEFQHLIIFAPT-TKLVQF--LEDGGNILVGASSFGREFDIDFSAVFDF-RGIGNPLLISVLRASPVAYSLITGFQTHKQ-SRILFVGSVEFFSNTNSKVSAELAAWVFQNSAVLRIYCINDQIYKVDVQATDMQLDFTMLDPHLRVFRAPDRHGVFTFRVDYRRRNQVMVTPPDHDQHPR--FLSDAYPYYVGSLNVLVGFVLFSA Mnele -----RTLVILEFLSDLSTKD-SDIVYKYATDYNNIIILAPS-VAFLTF--LDDGGNIVISASSIAAEVGVEITSVIDF-QGVGNPLVIDILRASSTAYSLVAGMQARNN-ARIVIFGSHLMLSDKNRDFTSNVIDWALRRNGDLRFYRITDEVYSIVIEESDVQLEFVRIDPFIRGFKVPDVYGVYQFKVDYDRIGQVSVRPFHHTEYER--FIPSAYPYYASAFSMLGGLFVFSF Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 -LTGPRALVLLDLWNDLEGRH-YNLTINDVS-YDHLIFLAPK-MKVVGF--MAEGGNVILAGSSLSREFDVEFTSVLDF-RGIGNSLLTPVLWAPQEAYSLVSVMQARNN-ARIAFLGSTEMLSDANRKFIEELTKWTFQEKSALDVYRIKDNMYTISLAEDDVQLELIMLDPYVRTLQLPDQYGVFKFMVNYKRPGTVGIHPFRHDQYPR--FISQAKPYYTSAASMGVGLLIFSF Mucci2 SATGSRVLVLLDFWQQLEDRQ-FQLLFREAQDFNHIIHFAPK-NSLVDF--VKKGGNILAATGVLAAEFDIELDAVFDY-SGTGLPLSTAILAAESDAFVLVGALQSRNS-ARVTFVGSLDVFSDKNEEFVKQLSQWTFQEKSVLKVYRVKDDIYHVDISENDVQLEIIMLDPYIRNVKLPDVYGVFTLKVNYKRPGQVSIRPFRHNEYPR--FLTAAYPYYASTGSMIAGFLVFSA Mydma SLSYGKTLVLLDFFSKLSDLG-HELVFKNADDYKHLVIFSPS-VEITSF--IDNGGNVLVAGSSLGSDCGIEFTSVIDF-KGVGNPLVLEILTASSTAYSLIGGQQSRNN-ARVVFCGSLDFFSDKNMKVALDVAGWTFQSHGVIRVYIINQQVYSIKIEEKDVQMEFFRIDPFIRQFQLPDVYGVFKFKVEYDRIGQVSVRPKQHTQYER--FIVSAYPYYASAFSMMIGICIFSV Neucr2 STSGNRLLVVLDFFADLEERE-FKITYETPKSYDHVLFLPVR-TKLHDF--VNAKGNILLALSALLSELDITLSLVVDP-RGVG-QLLNPILRAPRTAYSLVSTMQARNN-ARVTVVGSAEMLQDKNREFAKRVSGWTFQEIGVLKVYRVKNNVYTISLSEDEIQLEFSMLSPFHRVFTTPDQHGIFNFMVNYKRPFTVPVRHMAHNEWPRSYVISGAWPWIAGLGSTVVGFLGFVA Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SSSGSRLLAILELWADLEARG-YDVSIESSKSYDHLLILPPK-SKILDF--MNKDGNILLALSGLLLELDIHLQVVVDP-RVAP-ALLSPILRAPATAYSIVSAMQARNS-ARFTVLGSVESLEDKNREFAKQLTAWAFKETGVLKVYRIKNETYSIEVSEDALQLEFTMLSPFHRQFVTPDQHGIFSFRVNYKRPFEVTNRHFAHDEYPRSWAITGGWVWIAGLWSVIGGFLAFVI Phybl2 SVTGDQVLVLLDLWETLQDRD-FKLDFKSAVDYQHIIHFAPT-TALVKF--VNGGGNLLVGVSSLASEFDIEFTRVFDY-SGVGLPLVNRVLSAEDTAFVLIGAMQTRNS-ARATFVGSLDIFSDANEEFVSELTKWTFQEKSVLKVYRVKDDMYTLEISENDVQLEIIMLDPYIRHVQLPDVYGVFTFRVNYKRAGVVAIRPFRHNEYPR--FLTAAYPYYASVGSMIVGFLVFSA Picst3 DLDVQHALVVYDLLNNLNDN--YKVTLKTYDDYDHLVLLPSS-KKLLDY--INGNGNILVVGGVFLNEIGIYPFKLTDY-EGSANEHIFPIIKGSPTSFTLAVGFQALNN-ARLAWVGSEALLAEA------GLYKWTFQQQNVLKLYRIKDQSYVIGVSEDQLQLAFKMLDPYQRNFTVPDHHGMFTFELDYKRTGIVTVRHLANDEFKRSWDITNSWLYVASAFLVAVAWFLFVV Plicr1 SSSGDSVLVVLEFFSGLEDQG-YNLTFRAPKDFSHIILFAPE-TKLVAL--LSGDTNLLIALSSLASEFNLILTPLISF-SGIPNPLLVPFLHAPAESFALVTGFQTRDG-ARVTWVGGVELFSDENQQFSRDVAAWTFQETGVLRIYTTNDQIYTAYISQDDLQLEFTMLDPHVRTFRAPDRHGVFKFVINYKRKGTVPVVPPRHDGYPR--FLSAAWPYYAGAISTSVAFVLFSA Polpo DIGGKRTLVVLDFFKSLSDRG-YKLQFVRPEEYDHLILFAPT-SDIISF--VDAGNNVLIAGSSVASEVGMDITNVFDF-KGIGNELNYAVLTGASTAYSLVSSLQARNS-ARVTFSGSLELFSDNNQKFVENLVSWTFQERGILRTFTVKDDI----VEEDQLELEIIMLDPYIRDLKLPDVYGVYTFESTVRRPGRHPIRPFRHDSYER--FIPSAYPYYAASFSMLVATFKLHI Pucgr2 RVSADKILIVIELWSSLNARN-HQLSFRAAKDFDHLILFSPT-AKLVQF--LEDGGNILLAGSTFGREFDVDFSSVIDF-RGIGNPLLMSVLRASPLAYSLVSAFQTKKQ-SRILFVGSLDFFSDQNRKVVDHLTKWVMQESGVLRIYRVNEQIYKVDVQMKDLQLEFTMLDPHLRVFRAPDRHGVFTFKLDYRRRTQVSVTPLEHDQYER--FIFGAYPYYLGTLSVLASFLLFSF Punst1 SSTGDSVLVVLEFFDDLEGQG-YNLTFRAPKDFSHIILFSPE-TKLVSL--LEQGVNILFTLGSLATEFSLILTPLLSF-SGVPNPLLVPLLRAPAESFAVATGFQVRGG-ARAAWVGGVQLFSDENLQFIKDLVSWTFQESLVLRIYTIYNEIYTAHISKTDLQLEFTMLDPHIRTFRAPDRHGVFKFVVDYKRKGVVPVVPPRHDEYPR--FLSAAWPYYAGAISTSAGFVLFSA Rhior3 STTGNRVLILLDFWDQLQERG-FETIFKAADDYSHIIHFATK-SSLVNF--VKKGGNMLIAVTSLASEFNIELERVFDF-SGTGSPLSTAILNAESSAFILVGALQARNS-ARVTFVGSLDMFSNKNEEFVKQLTQWTFQEKGVLKVYRVKDEIYTIDIVEDNVQLEIIMLDPYIRHIKLPDVYGIFTFKVNYKRSGQVSIKPFRHNEYPR--YLTAAYPYYSATGSMIIGFILFSA Rhoto1 GAIAARVLVA--FLESLRDAG-YEVDTGTAQTFDHLIVFASP-HKLARR--LDAGANLLLITSPFAREFGVDFSFAVDY-RGAANPLLTTVLHASSTTFGLVSSFQARNN-ARVSFVGSFDLFSDRNAAFARDLVDWTFQKTG-LLVYQV----YSLEVASNDLQLEFGMLDPHVRQFKVPDRHGVFTLRVDHRRPGVMSVTPPRHDEYDR--FIGGALPFYTGAASVSAAFLIFIV Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 GTQTSRTLVLYDYLKDLEQRN-YKLEYLDINSFDNIIVFPTKGGKLIKF--FENEGNILCMSSPFLNELGIYPHVIRDFGESSAREQIVPILNAPRTSFTLVVGFQNLNN-ARLVWIGSSDFLKNKNQEFAKELLKWTFNEKSVIKSYKIKDKVYSVGFSEDDIQFELRQVDPYYREFILPDRHGVFTFLTDYRKIGVKAIRHLANDEYPRSWEISNSWVYISAICGVIVAWIFFVV Salro SASAQRTLVLLDFFSRLSDAG-LSLKYVQADSFDNVIVFSPS-VEMVDF--VDNGGNVLVAGSEFASEVGFEFNAVIDF-RGVGNPLAVSVLRASSTAYTLAGAMQARNN-ARVVLTGSIDMFSNENEQFVEALALWCFQERGQLRTYTITDEVYFLPIEENDVQLEFVRIDPFVRTFTLPDVYGVFQFRVDYNRLGQVSVRPLRHTQYER--FISTAYPYYANAFSMMAALFLFSF Schco3 SSTGNSVLVVVDFFNGLESQG-YQLTFRAPKDFAHVVYFAPD-TKLVEL--AKQNTNLLIALSPLAAEFSLVLTPLISF-SGVPNPLLVPVLNAPAHSFAVVAGFQVVNG-GRVMWVGGTEMFTDENAQFVQDIARWTFQETMVLRIYTINDNIFTAKISKNDLQLEFTMLDPHIRTFRAPDRHGVFKFVVDYRRKGTVPVVPPRHDEYPR--FLSAAWPYYTGAISTSVAFFLFSA Schpo1 QAARQTVLAVADFLQSLTDRD-FDVKTSYIKDYDNLILLSSQ-SKLLEF--VQSGGNLFVVAGSLGRQLDMFLSVVVDY-KGIGNPQTQPILRGNPTSYILVSVLQSSTG-ERVGLSGSIDMLKDENFLFARDLTNWVFQRKGVLQAYRIKDEMFSIDISLDDVQLELIMLDPYYRVLVAPDHYGDFTFKIEYKRPGTFTLRQFFHNEFPR--FLPHAYPYYASCFSVLGAFLLFCG Sorma STSGNRLLVVLDFFADLAERE-FKITYATPKSYDHVLFLPVH-TKLLDF--VNAQGNILLALSALLSELDITLSLVVDP-RGVG-ELLNPILRAPRTAYSLVSTVQARNN-ARVTVVGSAEMFQDKNREFAKRVSGWTFQEIGVLKVYRVKNNVYTISLAEDEVQLEFSMLSPFHRVFTIPDQHGIFNFKVNYKRPFTVSVRHMAHDEWPRSYVISGAWPWIAGIGATVSGFLGFVA Sphar YAHKPRTVVVASLIELLQSYD-HDVTVKQKADIDNLIILDNT-VDLMSY--VDSGGNLLIAGGVVARHAGFVTLQLVDY-NGPAGKLSFAVLRAPSTSYALVGGMEARNN-ARVLVVGSTDMLSDANEVAQKSMMEWITMRKSVVRTYTVMDEVYAIELEESDLQMTYTRMDPFVTRFSLPDVYGLFTFKVKYTAHGTLVIKPLRNNMHQR--WIPGAFPYYTSALSMMGGVLAVSF Spipu1 PVGGARTLVVLEFLKSLEERG-HNLSFKTASEFDHFLVLAPA-IAVLDF--IDKGGNVLVATSSLTYEFSADFSAVIDF-RGVANPLAEPLLIGAPTAYSLVSSLQARNN-ARVVFAGSVDMFSDKNLPFITALSKWVFQESGVLNVYRIKDDMFEISISETDMQFEAVMLDPYIRHFKLPDHYGVFTFKVDYKRHGTVQIRPFRHDQYPR--FLSPAWPYYVNVFSLMVAFVLFSG Sporo1 SATAHGVTVALGFWGTLRDAG-YEPTVESYEAVEHLIIFGST-TKLSAL--LNSGTNVLLALPPFAREFEIDMTQAVDY-RGALSPLLRSILSVPSTTYSAVSGFQARNN-ARLAVVGSLDVFSDRNAAFLADLARWTFGTTGQRRVYRVRDELYVLDVDSEDLQLEVTMLDPHLRTFQLPDRHGVFTLRVDHRRSGVVSVTPPRHDEYER--FIQGAAPYYGGALSVSLGLLVFVV Stehi1 SSTGDSVLVFLQFFGNLESQG-YELTFRAPKEFSHVLYFAPD-TKLVQA--LESNTNIIFALSPLASEFSLILTPLVSF-SGISNPLLVPVLNAPAESFAVVSGFQTRDS-ARVMWVGGIELFSDENEQFALDIASWTFQENKVLRIYTINDQIFDAYISRADLQLDFTMLDPHVRQFRAPDRHGVFKFLIEYKRKGTVPVIPPRHDGYPR--FLSAAWPYYAGAISTSAAFLVFSA Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr PYLGKRALVLLDYFAALENKG-YELTFARADDFDQLVLFAPA-TEVMEF--VRAGRSVVLAGASLAAECGLVFSYVLDF-RGIGEGLVLEVLSGSAFAYSLVTALQARNN-ARMVVSGSIELFSDANLEFALRLTAWAFQERGMLRLYRVKDDIFHTTIEESDVQIEFQMLDPYVRAFKVPDVYGVFQFKLTYRRHGQVVVRPFRHNEFER--FITQAWPYYTSAFSMMGCFFLFSF Treme1 SATGDRVLVVLEFWASLTDRG-FDLTFKKPNDYDHLIMFAPS-AKIIEA--QYTHLNTLYLLSPTMREYDLEFSVLLDP-SGTVNPFLIDVLHATKTAYVLVSALQTRDN-VRIGFVGSGQMFSDKNAAFAEDFTKWIFQERGVVKVYTKKDDLYSVTLAEEDLQLEFTMLDPHIRKFKAPDRHGVFKFMVEYFRPGMASVVPLRHDEHPR--FIVGAWPFYTAPISISFAFLLFCG Trire2 STSGNRLLVVLDFLGDLTARG-YQVSYETPRSYDHLLFLPSK-VKLVDF--VNANGNILVALSSLLSELDISLGTVVDP-HAVG-PLLTPIVRAPATAYSLVSVMQARNS-ARVTVLGSAEMLQDKNKEFARRVAGWTFQEIGVLRVYRVKNDVYTISLSEDLLQLEFSMLSPFHRSFTLPDQHGIFNFLVNYKRSLTVSVRHFAHDEWPRSFVISGAWPWISGIGATVTGFLGFCA Umbra1 SLTGNRVLVLLDFWSSLEDRE-YKINYSTPQNYDHVVHFAP--HSLIKF--VDMGGNLLIGLTPLLREFDIELHRVFDF-RGVGIPLLNRVLATEGNAFSLVSSLQARNN-ARVSVAGSLDLFSNINKEFTDELSRWTFQEKSVLKVYRIKDNIYTIEIAESDVQLEVIMLDPYIRHLTLPDVYGVFTFKVNYKRPGVVAIRPFRHDEYPR--FLSAAYPYYVSVGSMIVGFLVFSG Ustma22 SATGDRILVVVDLFASLSSRG-YKVDFKAPRDYDHLMLLSPA-SKLVEY--LKAGGNMVVGLDSLAREFSLEFSALVDY-RGIVNPLAFPLIVAPATSYSLVSGFQLASNSARAVFVGSTEMLSDANQLVVADLTAWTFQEKGVLKLYRINDHVYSVDVAELDLQVSFKMLDPYITTFQLPDRHGVFSFILDFKRTGTAPLRPFNHDEYPR--FLSSSWPYITGAFSTVTGFLVFCA Walse1 TLAKSKLLIVHDLVDVLD----YDIDVSHVRDYENILLLSNT-LALVDH--LEDGGNLLVASDSLAKQFSIGIVTTFDL-SSNSNPLSWTLLQSPP----IISALQTTKN-SRIVWSSSLDLFSNDNRQFVKNLIDWTFNKLNNVQVYYYNDEAFEVALSVDDLQLEFTMLDPYIRTFRVPDKHGIFKFVIDYKKKGRTTVAPIQHDRHPR--FLSHAWPYYTGVFSTIAGFLIFSV Zygro1 SVHASKTLVLYDFLDDLKSRE-YEIDYYTANSYDNLIVLPVK-GKLLQF--YNDGGDILSVTSPFLNQLGIFPYELVDLSSSSAREQIFPILAAPRTSYTLAAAFQNLKN-ARVAWLGSVDFLKNENGNFVQEVAKWVFQEKNVIKSYKIKDTVYEVGFSEDDIQFELKMLDPYYREFNLPDHHGVFTFETDYKRDGVKPIRNLAHSEYARSWDISNAVIYLSSIFSVIFAWIIFII [Cluster2169.fasta_al_trimmed; alignment length = 377] Allma1 AKDAGANEVRSL-ERAVLLTANINNMVKIA-KLAAIHAQRRLHFHDKGQWLRKQYQSFVTRLSLQVAAV-KLLLDLTAVSSAVHRIFLLLE-KDDVRFYLFKLTKIIQNAYFVLFP-ASNDALTKFMLVLGAIKHKRAFTDFVLNYL-R-LPVLMLMNARIIPNMAD--PRLLMTFLTESYDQGGSTSLLALHAVFTLIAEHNLDYPDFYKKLYNLFDRNLFHVKYRSRFFRLFNLFMQSTHIPVYLVAAFIKKMCRLALYAPPAAVLITLPFVYNMLKQHPQCMVLIHRDPFDMNEEDKARALESSLWEVVSLQSHYFPNIATVARIFQDRMTK-PGYNLEDFLDYTYQNLFETVSLK-KPP-LNYEISS------ Ashgo11 ------DEIKER-CKLVLSDKNYNVVVKLLQAFYLALSLAHVKLFERGDWCRKLYTSFKNKLSLGLDCI-DAYMRMLEQEALVQALFTYYKRYVDVQFYTQALAGGLAKWLALCYDSEDADE---IFVMENEARFKSNFESNWLHVLSL-ASIFLILHKRITPHFQQ--PTRLMDFLTDSYD--GVIPLLALNGLFDLMRRHNLEYPNFYTKLYQLVTPDMMHTKYRSRFMRLIDLFLSSTHLPANLVASFIKRLARLSLDAPPAAIVSVIPFVYNLIKRHPSCMIMLHDDPFDSTEQNATRAIDSSLWELETLMSHYHPNVSTLAKIFSQPFQK-LSYNMEDFLDWSYDSLLAAEKMK-VPS-LEFDRFD--EW-- Aspfu1 KRKNAKVKIQEL-EDQISESKYYNNIVTLI-SMAVAVSLCRVRLMALGAWLKERCREYQKALAWQVTAL-TLCMRIINERAVFEAVVQFAKVYEDVRYYTFVVSDYADVLISMLVP-GAEHKFENFHTLLSVNSHKKQAQNAWLAIL-Q-NDLLRNMVYTIEPWFNR--PELLMDFLTDSYNVGGATSLLALSGLFYLIREKNLDYPQFYHKLYSLLDADLLHSKHRSRFFRLMNTFLSSTHLPATLIASFIKRLSRLALNAPPTAIVVIVPFIYNLLKNHPTCTFMLHRDPFDVNEGDRTMAIESSLWEIETLQSHYHPNVAAIARIISEQFTK-QAYNLEDFLDYTYQGMLQAEPFK-RPV-VEYHIPKRGLWNF Aurde31 KRKRDSASVAEL-EATLLDPPSLNPLADLLVHMAAIFAAYRVSLVARGTWLYARLDEYTAFLALRDGAM-QILFSLLKHLSIVRGVL----AYDDLRWLFLRMAAVMSRAFGILLP-TSSKDL-TFFLMHVPPAHRAQLVTAWLAVLPR-ISALSILHLRLVPHLKKEEAVRTMDWIAGCVDYGDASGLLALNTLFELMTTMNLDYPDLYVRLYAYLDRNTLHFKHRARFFRMLERMLASTHLPATLIASFIKRLSRLSLSAPPAAVVAIIPLVYNLLKRHPTCMPLIHRDPYDPSETSKSRALESSLWELQSQTAHYHAPTAVLAKVFSEPFTK-PNYAMEDFLDHSYSTMFDAERIK-TPA--------E-IWAF Batde5 ------ESIRQI-SKGCLTDANLNDILSLL-KYAAITSLQFVKLIASGTWLRENRAQYFEVLRLQLVSF-EKHIQLLKNIALVEVLL--LNKHDDLRFFFFRASKVLQNAYTIISP------------FTQPTIYCRAFSNCWLAFM-R-HSCLESLHQKIIPYLSK--PVLLMDFLVDAYNTDGIIRLLALNGIFTLITEHNLDYPDFYAKLYALFDSNLLHYKYRARFFRLADIFLSSSYLPSYLVAAFVKRMGRLCLTAPPAGIIMILPFIFNLMKRHPSSIQLIHTDPFDFTEMDKCNAQESYLWEIQALQMHAVPTVSGLARVFQDSLAK-PLYDLEDFMDYTYKSMVDSEKKR-KPA-VSI----Q-EWLN Botbo1 KRKTSK-EIRQT-EEILTLASSLNPLADLV-TLKAAYALYRVLLISGGKWLAARFEEYVDMLALKTASL-QILFSLLKHLSVVRALLTWFGVYDDLRWFFFRATLILHNVLSFLMP-TEASELNSFWILHSLASHRAQFSICWISLVRK-LSALAVLHRGVLPHFNR--PVRLMDWVGGCVDFGGSVGLVALNALFTLIKDHNLDYPDFYTRLYAFFTRDVLHLKYRARFFRLTDLFLSSTHLSAALLASFIKRLSRLSLSAPPAAIVMIIPFVYNVLKRHPALMVMIHRDPFDANEPSLTNAISSSLWELATHREHYISSVSTLARIFTEAFTK-APYSMEDFLDHTYATLFETEKIR-KPA-LKMELVSE-LWSF Botci1 ---------------------------------------------------------------TASTGL-TLCMRMLKIEGMVQVLIKFVEEYDDVRFYTLEIEKLVDTVYEILVP-ESKDELEDFYILYSLTEHKKRAQGAWLALM-N-MEILSKITDFIAPWFTK--PELLMDFLTDSYNSGGSTSLLSLSGVFYLIQEKNLDYPSFYRKLYSLLDTGILHSKHRSRFFRLLDTFLSSTHLPVVLVASFIKRLSRLTLHSPPSGVVAVVPWIYNLLKKHPTCLFMIHRDPFLMDEEDLTNAIDSSLWEIVTLQSHYHPNVATLAKIISEQFTK-HSYNLEDFLDHSYGSMLESEDVK-KPV-VEYEIPKK-LWNF Caeel ------DDLDQFFHDDAEQN-----------DF---------------KFLQE--CEYPDDIIVSTKSL------------VLRGIAKIFGRYD--------IFHLIFNLFNFLVPHPTDRLFRQFCVKRKLTWISTDYDNVWMAVMNG---TLKLIPQNVISKLKA--PFKSADFFFKMFDKTDYHGILSLGAIFRLISEHNFEYPKFYDKVYSLTNPSLLYMSQKESILTLLDSFLSSTHLPTYITASFLKRLSRCLLLAPIDAQEPILGLIRNLVIRHPNCSELVHRDPFDNDETDKTRALESSLWEMKLLQCHWNQSVRKRAHFVDKSIQKIESYVGEDGEAEKYRKLQDGDKFAPKAVGVNSEAPK--LWKI Canalb1 KKVKTAEELTNL-SKEIDESK-FNNLVPLLEQFKLSLLLYRNKI--NDKWLSEKYTTFKDIISLQLDLL-DIILNFIRLESLTESILK-FQKYWDLQFYFFNLSEVLANFLTVLFNEKT--EEEPLWILYKHTLFKSQFQKSVIAML-S-YPVLMILHKRIIPYMSQ--PQSLMDFLTDCYDL-LIVPILALNSLYELMKNYNLEYPDFYSKLYSLLTPELLYTKYRSRFFRLCDLFLSSTHLSANLVASFIKKLARISLAASASGVVIIIPFIYNLLKRHPTCMIMLH-DPFNSEEKNHTEAIKSSLWELDTLMTHYHPNVATLAKIFGEPFRK-PSYNMEDFLDWSYNSLLQSEKFKDKSA-LEFEEFD---WTL Cangl ------EETKKI-TKKITASKDYNSIVKLVQSLFLVVALFQIKLFSKNKWCRKIYESFKNNLSLTLDCL-DVYMQLLEQESLIKALFKYFKEFVDVQFYFLSFLDLQAKWLAIVLTNGDVEE---IFVIESESKFKSNLEKNWLLLLN--SEILLILHRRVVPYLQN--PTKLMDFLTDSYNL-DAVPILALNGLFELIKSSGLEYPNFYGKLYQLLTPDLMHVKYRSRFFRLMDIFLSSTHLSAHLVASFIKKLARLSISAPPGAIVTVLPFIYNLLKRHPSCMIMIHDDPFDAAAVDQTHAMESSLWELKTLMDHYHPNVATLAKIFSQQFKK-MHYNMEDFLDWSYDTLLEAERLK-VPT-LEFEEFP--AW-- Capow TRAIEAASVSAS-QQQLRHA---GDLLAVL-KAAALLALRRVQFLHAEPWLHERYLEFVRLAVIQATSI-GVLMELLSAEAILAALVGYLEKFDDVRFYTYKLASLIQHIFLLL---ANTADLNGFHCLKNLTEHRAVFTDCWLALL-R-LPVLIILDEQILPHLNK--PKLLIDFLTESYNVGGVVSVLALSSLFTLITKHNLDYPEFYAKLYALLDPQIFHVKYRARFFHLADIFLSSSHLPSYLVASFAKRLGRLGLSAPLPAQKLILQIIFNLILRHPSCMALVHRDPFDADEPNATRAAESSLWELDAIKSHFSHDVTQQAAVFEGKITK-IEYDVNDIVEDSYASLFSNLKFK-EP--LSFDTVGQ-LWEM Catan2 TGGHAAATIRTL-ERSLILSANINNIPKLL-KYAALSSLRRLHFTDQGKWLRKHREAYVTRLALQVTAA-KLLLDLSLDYSVVQPTLVFVE-NADARFYLYKVAKIITNAFHLLLP-CALPNSPTFLIVTQAKEHKRAYSEFVLQYL-R-LPVLMLTPTRLIPNLTD--PRLLMTYLSESYDQGGSVALLALQSVFVLIAKHNLDYPDFYKKLYTLFDRNLYHVKYRSRFFRLFTTFMSSTHLPAYLVAAFIKRMARLALTAPPAGILIMIPMVYNLIKQHPQCFVLIHRDPFDMQAEDNAKALESSLWEVVTLQGHYFPNVASMAKVFTEKMSK-PRFEVEDFLDYTYGNLFETVVMK-KPP-LSYKVPEQ-A--- Cioin HQKHN-KSISSL-VEGVIAKKNANDLVLIIENIEAISGAHEIHLFESDAWTNEQYHSYFDCLSVRKSAL-ETCAKIIQCYGVTKCLLREFFKYGDIRYFVMRLSTILNNCLVLLMPKEDSACLNSYIL--QISQHRKRFGQMWLEFL-K-LPVLVILHASLVPNFSQ--PRLLADFLINTYNRGGGLSLLSLHGLFVLMHNYNLDYPDFYTNLYTLLHPRIFSTKYKARFFHLLDLFLSSTHIPSYMVAAFVKKLSRLSLIAPPHSINTMVNMILNLMRRHPSIRHMIHCDPYIENEKDLCKAAESSLWELHTLKHHYCPKIAKLAS--AKSLGT-KETDIHENLEDNYKDFFDEVEFK-EP--MNYTQPNN-LWTG CocheC53 KRKRDPSEIVQL-EAQILESKYYNNIATLL-QRLAAVALCRVRLLVTGSWLKERYRELCNMLPKQSVAL-TLLMRLVKEEALIEVLLKYLKQFDDIRYQTFQIKKTLANSMSLLVP-KSKAEIQNFYVIPSLQAYKEKAQAAWLATM-R-TGILTTFSYQIAPWFQQ--PEILSDFLTDSYNVGGATSLLALSGIYYLISEKNLDYPSFYYKLYSLLDDGLLHSKHRSRFFRLLDTFMSSSHLPATLVASFIKRLSRLALHGPPAGIVVVIPWVYNMFKRHPACTFMMHRDPFDMAEADLTNAIESSVWELVALQSHYHPNVATLAKIISEQFTK-RSYNLEDFLDHSYTALLDVEDLK-KPE-VEFEIPKH-VIEA Coere1 ------ESVRKL-EANVLSSQNLNDIVKIF-KIMAVNSLGRIGLWAKGEWLRANFNMYTDLLPMQIAAM-RMLFQLLSKEGIIESVLSYLNVYDDLRIYFYRFAKMARNAFAVIIPKTDIADIKSFWIVLSPAVHKKAFSEAWLAFM-R-LSVLLTMHKRIIPHMTD--AKGLMDFLSNSYDAGGSISLLALNGLFTLITEYNLNYPQFYEKLYALLDRNLLHVKYRARFFRLLEVFLGSSHLPAYLIAAFIKRMSRLALSAPPAGAVTVIPMVYNLLKDHPSCMVLIHRDPFDSEESDKCQAMKSSLWELETLQHHYYPNIATLAKVFNEPFHK-PKFMLEDFLDHTYATFFESDKPK-K---------------- Conco1 KRKRTSDEVPKI-KKSILEGKNWNEILKLL-EYLSIKAIQQITWIKSGNWTLEIFQSYQTQLALQVGAI-ECYFNILKQQALVRQLFKFCLGFDDTRYHTYFISKFF---FDVLFP-SSNADIKNYWGSFELKGHKKVFTDAWVNLL-K-QPTLILIQKKILPNINQ--PLLMLDFLTISYDQGGVISLLALNGLFDLINTYHVDYPLFYEKLYKLLDWDLLHVKYRSRFFRLMELFLNSTHLAAYLVAAFIKRLSRLTLQAPPAGIVMVVPVIYNLLMKHPSCLSLIHRDPFDFNESDKTKAMDSSLWEIQTLTNHYHPTVSSLAKVFSEKMNK-PNYPLEEFLDHTYNSMMDSDPIK-KPA-LAIDATKL-STKL Conpu1 KRK---DELKLL-ETQICSASSLNQLADLL-ELRAIYSLYRVVIVTSGRWIWDKLEAYVNILGLRISAL-EILFSLQKHLSVVSAILKWLSVYDDVRWWFLRSTTVLDNMLSIMFP-TEPSELNSWWVLHSLQAHRAVFTRAWLSFLSR-FSVLNIMHRGVLPHLTR--PVLVMDWISACVDFGGTVGLLAFNALFTLMRDYNLDYPSFYTRLYAFLDRDVLHLKHRARFFRLTELFLSSTHLPATLLASFVKRLARLSLTAPPAAIVMVIPFTYNVLKRHPALMVMIHRDHFLPEEINNTNALDSSLWELYSQRQHYDPAVSGLARIFEEAFTK-PGYNIEDFLDHTYGTLIETERIR-KPA-LAIDLKPE-LWAL Copci KRKLDPSQIKAL-EESLAEATSLNALVDLI-QLKGIYALYRTLVISTGAWLWKRLNEYTDYLHLRTSSI-QILFSLQKHLSITNGLLTWLSVYDDVRWFFLRAATILKNLLLILFP-TEQSELNAWWVLHSLASHRAVFTRTWLTLLPR-VAVLNIMHRGVLPHLTR--PILVMDWIAGCVDMGGSLGLLGLNALFTLMKDYNLDYPSFYTRLYAFLDRDLLTSKYRARFFRMADLFLASTHLPATLLASFVKRLARLSLNAPPAAIVMIIPFTYNILKRHPALMVMIHRDPYSPTEPNSTNALSSSLWELYTHRSHYHATVSTLTKIFSEAFTK-PNYSMEDFLDHTYGTLFDTEKIK-KPP-LSMDCDKE-LWGF Croqu1 TKTSTKQQIRQY-ESDIQLSQDLNPISDLN-NVTTIYALHRITLIRQGEWLKERYEEYVTSLQLALDGL-TILMSLVRSESLVKALLRYFNYCDDIRYHFLKAAHICINLLHYLMP-TESDELDQFWTLLSLKSHQKVFSDCWISLL-R-LGVLNILHDQVIPHMID--PKILMDFLTDCVDIGGTIAILALNGLFTLMSKHNLDYPAFYTRLYALLDRSVLHVRHRPRFFRMLNTFLSSTHLPVNIVASFLKRLSRLSLFAPPGAIITIIPFCYNLIKNHPSCMSMLHRDPFDSEEIDKSGAVFSSLWELASLRSHYLASIATLSKVFIEAFDK-PNYNLEDFLDHTYKTLFETEQIR-KPA-LSLFTNSQ-IWRF CryneH991 S-KQTSAQVQKL-EASLGTDFNPNPLLPLI-ALKAVWALHRVKYIADGGWIRERLLEYVEILALRSSSI-PLLFSLLPPLSLLHYFIDFWAVYDDIRWAFFKAAQSTDNLLTLTLP-KVPADINTFYLIYSIPSQTTVYTSLWEFILSS-VPILVGLHQGILAHFKKERRLRIADWLGSLVDGGGPMAMLAMNGLFVLMTEYNFEYPNFYTRLYSLLTPALLHTKYRARFFRLLTIFLSSSLMPSTIIASFIKRLSLLCLTAPPQGIVMVLPFIYNLFKKHPGCMVLLQRDPFDPEEKDKTQALESSLWEIAALQHHYLSSVSTLAKVFGEPFTK-AEYNMEDFLDHSYNTLFETERIK-NPA-LSIGI--Q-LWAF Crypa2 KRKRPAVDILSL-ETAILESKNYNNITVLL-DTLAVIALCRVRLLAAGHWLRDRLAEYHEIL-YAMTIL-TLSMRLLKTEGIVGALCNFVDEFEDVRLYTFKVHDIIDILFELLVP-ESSEELEDFYVLFSIAKHKKQAQEAWLALM-R-LELLDVVSRVVAPWFIK--PELLMDFLTDCYNTGGSMSLLALSGVFYLIQERNLDYPAFYTKLYSLLDADILHSRYRSRFFRLLDTFLASSHLPAALVASFIKRLARLSLNAPPSAIVTIVPWMYNLFKKHPTCTFMMHRDPFLQDEEDETRAIDSCIWEIVQLQSHYHPNVATIAKIISEQFTK-QFYQLEDFLDHSYGSLIEAENVK-KPV-VEFQIPKK-LWEF Debha1 KQKKTSEEIQNL-GDQIRTSKHYNNFVQLLEQYQLSITLYKCYLLKNDKWLLDKYDAFKKIISLQVDLL-EIGLNLVKLESLVEALLK-FKKNWDLQFYFVNLHETLANFYCIFFTPETEVEQEKTWIAYKISQFKMQYQKCIIAIL-S-YPILLILHKRVIPYMAQ--PQSLMDFLTDSYDV-GVVPILALNSLYELMKRYNLEYPDFYTKLYSLLTPNLLYTRYRSRFFRLCDLFLSSTHLSANLIASFIKKLARLSITSSASGVVIVIPFIYNLLKRHPSCMIMLH-DTFNNDETDKTGAMGSSLWELEALMSHYHPNIATLAKIFGEPFKK-LNYNLEDFLDWSYISLLDSERYK-TVA-LEFEEWD---WCL Dekbr2 KRARKAANIQKL-EAETKKSKYFNNIARLLQHLSLVASLTRIWLLSKKGWLQAKYSEYFDSI-FQIYGL-SSVMNIVKAESVVRALIQYFNAFWDVKYYFFRLKMSLANLITLVYPRMDADYTDTTLVVSDLSTFRSNFEKSWIILLQS-KEILFILHKRVIPFMNN--PTKLMDFLTDSYNLGISLSIVALNGLWELIKKFNLDYPDFYTKLYCILTPELLHLNIRSRFLRMLDLFMTSTHLSATIVASFIKRLSQLALRSPAPGIIAIIPFVYNLLKRHPTCMLLIH-DPFNPDEKDKTNALDSSLWELETMMNHYHPQVASLAKILSQPFSK-NNYNIEDFLDWSYQRLLEGEKVR-SID-LEFETWD------ Dicdi TKKVLSEKIKEI-ESQVIESENSNKILEII-KIESIKSLERINLFDSSHWLYKIYVGYLELLSIQLPTL-TTLLNILKRESLISTMMNYLSKYQDLFYYSLVTIALIENLFDFLVP-----DEWEFWVLTKISSYRSIFSKSWISFL-T-LPVLLGLPDRVFPYLTD--AKVLLDFFTNSYDLGGVTSILALNGVFILITKYNLEYPDFFKKLYSLFQPGVLYAKYRARFFKLADLFLSSKSLPNYMVAAFIKRCATLCLISPPYGSLILLPLIYNLLQRNVNCHCLINNDPYDPIEEDKCNAISSSLWEIQILRDHYAPEVSKMAKLFDNGLKN--IIDLNEFSFVTYQVMYENS----KP--LAYQQKSS-DWKF Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba KRQAIAKEIQEI-VSAVRQDRELNRLVRLE-GLAAIEASVGFQFIGTLSWTRDRYQVYVNLL---LCCL-PVLMQLLSIETAMEAVLRYL-AYPDLRYFMLRLRRLIANVLELMVP-------------------RSVYSLAWFATV-R-LPMLGALPRQVYPHLTG--LTPLVDFLTELFTKTGVLALLSLDSIYILMLKHNIEYPDFYNRLYSLCDDRLPRLKYRARFLTLTDLYLQSPLLPGYIVAGFIKRFARLALTAPPSTAIALLVFVYNLLKRHPSCMVLLHRDVYNTEEPAKCRAIDSSLWELHAMRSHYSPTVSNFVKNFMEPLRR-SSLDLAQNLESTYESLFEAERRK-KP--VTFERGVE-LDEV Fomme1 ARKRKSKSIKDL-EDAVSAAASLNPLSDLL-KTKAMFALYRLLISQKGAWIIARLDSFTDLLTLRLSAL-RILFSLLRQMSIVRALLTWLNVYADIRWFFLRAYVVIANALTILIP-SSSDTKNHFWVLHAPAAHRAVFTRAWLALLPL-LSVLVVLHRGVLPYLTR--PVLIMDWVGSCVDHGGYVGLLALNALFVLMREYNLDYPSFYTRLYVFLDRNVLHTRHRARFFRLTELFLSSSHLPATLLASFVKRLARLSLSAPPAGVIIAIPFIYNILKRHPVLMCMIHRDSFNENEPNLTNALGSSLWEVAAHRQHYHAPAATLAHIFEEAFTR-PGFSMEDFLDHTYTTLFETEKIK-KPAVLEYELEHT-LWVF Fusgr1 KRKRSSAKILLM-EQGILESKNYNDITVLL-TTLATVALCRIRLLAQGGWLRKQFGEFKKTL-LAPTAL-TLCMRTLKAEGIVLSLIEYVEQYDDIRYYTLDVKHIVDRCFALLVP-ESAEQLEDFYVLRNVNQHKKQGQEAWLALM-T-LMILDIFTTVIAPWFTK--PELLSDFLTDCYDAGGSTSLLALSGVFYLISERNLDYPSFYAKLYSLLDRDILHSKHRSRFFRLLDTFLGSTHLPAALVASFIKRLARLSLNAPPGAIVFVTPWIYNLLKRHPTCTFMIHRDPFLPNEADHTEAIDSCLWELVQLQSHYHPNVATISKIISEQFTK-QSYNIEDFLDHSYATLLEAEEIK-KPV-TEFHIPKK-LWDF Galma1 KRKTHK-RVKQL-EDQLTNASSLNPLADLL-TLKAIYALYRVIIISNNAWIWERLQSYVDFLFLRTSAL-QVMFSLLKYLSIVTSLLSWFSVHDDIRWFFLRSATLLVNLLSILFP-TEQSELNAWWVLHALSSHRAVFTRAWLTLLPR-LSALNLMHRGVMPHLTR--PILVMDWIGACVDMGGSVGLLALNALFVLMKEYNLDYPSFYMRLYAFLDRDVLHLKHRSRFFRLTELFLSSTHLPATLLASFVKKLSRLSLTAPPAAIVMVIPFTYNILKRHPALMVMIHRDPFIVEETNQTHALESSLWELLSHTQHYHAPVSTMCKIFSEAFTK-PGYSMEDFLDHTYNTLFETEKIK-RPA-LAVE--SE-LWVF Ganpr1 -------------------------------------------------------MDFL----------------------------------------------------------------------------------------------------------------------------GGVLSILALNGVFALMQKHNLDYPNFYPKLYRLLDDRVMRVKYRSRFLRLLDLFLGSTHLPAYLVAAFAKRLSRLLLTAPPAATVAVLPLIHNLLKRHPACLVLIHRDPYDHAEEDKCNALMSSLWEVASLRGHYLPVVKGLARAFEDRLGR-EEFQVEEFLDEDWVSLIEAEPIK-TPA----------GWDR Gloin1 -MQSSEEQIKDL-EQRISVSSNYNNIVTLL-EYSALYALYRTPLLSKGIWLRDNYVQYVNTLGLQIPSL-NILLNLLKIESVVEGLIKYWNTYDDLRFYFLKASKIIENTFSILMP-TDASEIDEFWTLLQLSAHKRVFSDCWLALM-K-LPILLIMHKKIIPHMPQ--PTLLMDYLTESYNAGGVTSILALNGLFTLINEYNLDYPDFYKKLYTLFDRNLMHVKYRSRFFRLADLFLASTYLPAQLIAAFIKRMSRLSLTAPPHGIVMIIPMIYNLIRRHPSCTVLIHNDPYNFDEPDKSNALESSLWEMKTLQDHYFPNVATLAKIFQAKFTK-PSYNLEDFLDHTYLTLIESEKSK-KPA-LSCERPKK-GWEV Hisca1 -------------------------------GL-------------------------------GIAVL-SLFMRLIKEQSLIVALIKFLNEYHDVAIYTLLLSEFTDTVISLLPP-PPDHEFENFYALLSVSAYKQRVQATWLTVL-R-SNLLRLMSHFIAPWFLK--PEMLMDFLTDSYNHGGSTSLLALSGLFYLMQEKNLDYPQFYPKLYSLLDADLLHSKHRSRFFRLLDTFLSSSHLPATLVASFIKRLSRLALNAPPAAIVAIIPWIYNLMKSHPTCTFMLHRDPFDPMEPDRTGALESSLWEIETLQSHYHPNVASLAKIISEQFTK-QAYNLEDFLDHSYQAMMGMEGFR-KPV-VEFQIPKRCLWDF Klula1 ------EEIKQV-WKSISTGKHYNSLVNLIHGYYMTIALSQIKLFERGEWCKKLYLNYKVKLSLSLDCL-DSYMKMLHHESLLVALFAYYKKNFDIQFYTQSLISLLSKWLALC---GSPDE---IFVIENDAKFKSNLETNWLHCLNL-ANVLLVLHKRIIVWFHQ--PTKLMDFLTDSYN--GIVSILSLNGLFELMKKYNLEYPNFYSKLYQLLTPEVMHVKYRSRFFRLVDTFLSSTHLSAQLVASFIKRLARLSVSAPPGAIVSIIPFVYNLIRKHPTCMILLHDDPFNNEETNLTNALSSSVWELETLMNHYHPNVATLAKIFQQPFQK-LSYNIEDFLDWSYDSLLQAEKLK-IPA-LEFERFE--KW-- Lacbi2 KRKLQPQKIKEL-EDELIKAASLNSLVNLL-DLKGIYAVYRTVIITQGRWLWERLNSYVEFLFLRTSAL-QILFSLQKHLSIVSALLTWFSVHDDVRWFFLRSATLLTNLLSILFP-TEPSELNSWWVVHSLSSHRAVFTRTWLTLLPR-LSVLNIMHRSVLPHLTR--PILVMDWVGTCVDYGGSVGLLALNALFVLMTEYNLDYPSFYTRLYAFLDRDVLHLKHRARFFRMIERFLSSTHLPATLLASFVKRLSRLSLAAPPAAIVMAIPLTYNILKKHPALMVMIHRDPFDAKETNATQALESSLWELLSHRNHYHATVSSLCKVFTEAFTK-PGYSMEDFLDHTYGTLFDTEKIK-KPA-LAVEYSKE-LWTF Lenti61 KRKTRERTIQDL-EKQLTVASSLNPLADLL-DIKAIYALYRVVIITNGAWLLERLHSFVDLLSLKTSSL-DILFSLQKHLSIVSALLTWFSVNDDIRWFFLRAAVLIGNLLSILFP-TKGSELNSWWVLHSLAAHRAVFTRAWLALLPQ-LSVLNVLHRGVIPHLTR--PILIMDWVSSSVDLGGTVGLLALNALFTLMKEYNLDYPSFYTRLYGFLDRDVLHLKHRARFFRLTELFLSSTHLPANLVASFVKRLSRLSLNAPPAAIIMLIPFTYNMLRRHPALMAMIHRDGFDASEGNLTNALESSLWELYTHRQHYHASVSTLARIFEEAFTR-PSYAMEDFLDHTYGTLFETEKIR-KPA-TALELSQE-LWTI Malgl1 ------ERVKKL-QLQIASSTDLNPLAHLI-KEKALTLAARVHVDEHGRWLQSQWNGFIMLLAVQHSAL-QIVMTLQTAASLIQTLVEFLEVYDDVRFFFCKISRLLSHARTLLIP-TEPSHLNHFLVLHTLSSQRQAFAAAWLSLL---LPILVRLHAQILPHLPN--PTMLHDFLVDCLDTKGTTALLALNGLFTLIVHHNLDYPAFYTRLYALLDASVLHTRYRSRFMRMLDTFLASMLLPVAIVASFVKRLSRLSLRATPAALIEIIPFIWNLLKRHPSCMQMIHRDPFDPYEPNHTRALESSLWEISTFDTHYLGSVSTFASILAEPFTQ-QRYELEDFLDSTYSTLFETETLK-RPLDIRLAVPPR-LWHF Mellp23 TNTSRKQQIKEL-ESHIKLSQDLNPISDLI-NVTTIYALHRITLIRQGEWLKERYDEYIECVQLSLDGL-TILMSLVRGESLVKTLLRYFNYCDDIRYHFLKAASICQNLLQYLMP-TESEELNQFWTLLHLKSHQKVFSECWISFL-S-LGVLNILHLQVIPHMPD--PKILMDFLVDCIDLGGTLSILALNGLFTLMSKHNLDYPAFYTRLYALLDGSVLHARHRPRFFRMLNTFLSSTHLPVNIVASFIKKLARLSLFAPPGAIITMIPFCYNLIKQHPSCMSMLHRDPFDINELDRSGAIFSSLWELSSLRSHYLSSISTLSKVFSEAFDK-PNYDLEDFLDHTYKTLFDTEQIR-KPA-LSLFATSQ-IWKF Mnele ------EQLSVL-TAKIMSDSYTNEIATILDMLAVLSSLRKIKLQTNRQWMRETYNDVFTAIQVQDSAF-SISLSFLTAETFVEQVL-------DWKFAALKFSKLHDFVYQLL---SELS-------SKTIHHICKAYNSTWVLFL-K-MPILSSLHENVIPHMHN--PKLLIDFLVDSYNLGGTASLLALNSLFILITKYNLDYPSFYPKLYRMLTPDLLHTTYVARFIMMLDIFLKSPLLPAYLVAAFAKRLAHNALQAPPHVVIIVMRFITNLVKLHPSVKRLVHRDPFLYAEEDQCNALQSSLWELEVLAEHYCPAVPAVVKTLRKPTDE-ILVGLG--LDKDYDGLFKEYKMWNKPP-LEFEEPVD-IFSF Monbr ------QSIERA-EQRLIGGEHIEELPKLI-DYTACRACYNVSYVR--SFLLAQVAELQSKLYMQALCL-VLRLNTNKKETALEALFRYMTQY-DVQFAFLRQRGSLTNMYMVLEPLSDGQFLDAFDAQQSIKQLKKAFTDAWVRFL-Q-FKVLSRLADSVMPHMTN--PKLLLDFLTHVYDQGGVPAALSLDALFILMYQYNLDYPRFYHQLYRLLDGPAMYARHRGTLLPLIDKFLSSTHLPLYMAACFAKRLARLALMAPPSAGAALAQLVYNLIKRHPKLRILAHRDPFDMDAELEAHGTESSLWELEMLQEHYLPEIQDAMALLKT-----PAYRVDKMAGKTYTTTIKAAAVP-EVA-TTFVEPE--LWTA Morel2 KRNRSEEQIRLL-ERQVAESTHFNNIVTLI-QFAAMHALFRVPMLSRGLWLRENYVKYLNRMGLQVPAL-KILLDIVKLESIVDALLKYFGFYDDLRFYFLKAAQIIENAFAIMMP-TEAKELDEFWTLLTLFNHKRVFSDCWTALL-K-LPTLLIVHKRIIPHLPQ--PTVLMDFLTDSYNAGGAISLLALKGLFVLITEHNLDYPDFFQKLYMLFDRNLMHVKYRARFFSQVDIFLSSPLLPAQLVAAFIKRMSRLGLSSPPASIVIIIPLIYNLLKRHPTCMQLIH-DSYDALEDDKSNALQSSLWELQTLQNHVAPNVATLAKIFNEQFTK-PSYNLEDFLDHTYATMFQNEKRK-GAA-IAVDPPKP-GWES Mucci2 ------QKIRTL-EAGLS-DSNLNNIVEIT-KYAAIHSLNRVSFLMAGAWLREQYSDYLAHVGLQLPAF-TILMNNIKSESIVKEIIKYLNVYDDLRHYFLKAAK--NNVFAILMP-TEASEIDEFWTLLQLSVHKRGFTDCWLKLM-K-LPILLILHKRILPHLSE--PKLLMDFLTDSYNVGGAVSLLALNGLFTLITEHNLDYPDFYTKLYSLLDRNVMHVKYRSRFFRLLELFLSSAYLPAALIAAFIKRMARLSLTAPPAASVIIIPFIYNLLKRHPTCMTLIH-DPFSMDNLNECRAIESSLWEVQTLSQHYYANVSTLAKIFGEQFLK-PKYNLEDFLDHTYATV------------------------- Mydma ------AQIQRICENK----KNSNTISDLL---VANSILYGVYYINDGLWLKTNYEAFVEILSIQLECL-MSLFNLMKVEYIMEQVVSYLKSF-DIQYYCVKISLMLFNVYKILLKKENKEESENFDLTKLIKKYPVVFSSAWLSFM-Q-FSVLVDLDKKIMPNLSD--PKMLIDFLTDSYNIGGVTSLLALNSLFVLINQYNLDYPDFYKKLYNLVDPGIFYTKYKSRFFHLLDLFLSSTHLPVYLVAAFIKRLARILLYSPITDLKMVLVFIRNMFFRHPSSLILIHRDPYIYEEVDKCNAIDSCLWELNTLKSHYSSEVLKQVALFKKDLPS-DEADVSDYFDFTYEDMFNSKNLN-KPP-LNFHKGNE-MWVL Neucr2 KRKRSESQIQNL-ESQINESKHYNNIATLI-EYAAAEALCRVRLLASGKWLRDRLNDHHKAL-LATQAL-VLAMALLKAEAIISALLKFIDEYDDIRFYTFEIKDFLNTVFNLLIP-ESSEDLEDFYILRSLSQHKKRAQEAWLALM-H-LGVLDVMASSIAPWFIK--PELLMDFLTDCYNTGGSISLLALSGVFYLIQERNLDYPSFYQKLYSLLDTDILHSKYRSRFFRLLDTFLGSSHLPAVLVASFIKRLARLALNAPPSAIVVIVPWFYNLFKKHPLTTFMMHRDPFLPDEEDETHAIDSSLWEIVQLQSHYHPNVATIAKIISEQFTK-QAYNLEDFLDHSYGSLIDAEEVK-KPV-IEFMIPKS-LWDF Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 KRKSGKSTIQEL-ENQIAESKGYNNIATLL-SMAVAVSLCRVRLIAGGAWLKERCLDYQNAL--QIAAL-TLSMRIVKERLIFAAIIKFVKEYEDVRYYTFTMADYAEILIKILVP-GPEHKFENFYALVSANSHRKQAQEAWLAIL-R-NNLLRMMVHNIEPWFNR--PELLMDFLTDSYNVGGATSLLALSGLFYLIQEKNLDYPQFYTKLYSLLDSELLHSKHRSRFFRLLNTFLSSTHLPSTLVASFIKRLARLALNAPPPAIVVIVPFMYNFFKNHPTTTFMMHRDPFDPNESDMTNAIESSLWEIVTLQSHFHPNVAAIARIISEQFTK-QAYSLEDFLDHTYAGMVTADNLK-KPV-VEYQIPKRNLWEF Phybl2 -------QIKKL-EADLS-DTNLNNIVTIL-EFAAIHALHRVKLLMNGLWLREQYIEYLNHVGLQVPAL-NILMSLLRTESLVDAIIKYVNVYDDLRHYFYKAAEIMQNVFSILMP-TEESEIDEFWTLLQLKVHKRSFSLCWIAML-K-LPTLLVLHKRVLPHMAE--PKMLMDFLTDSYNQGGSISLLALNGLFTLITEHNLDYPDFYQKLYNLLDRDILHVKYRSRFFRLLDIFLASAYLPAGLIASFIKRLARLSLTAPPAASVIVIPFIYNLLQRHPICMKLIH-DPFVYEEKSECKALESSLWEMDTLAEHYYANVSTLAKIFKEQFRK-PKYNMEDFLDHTYATV------------------------- Picst3 AKARKNEQIHSL-IDEVHKSK-FNNLVELLNQYQLTFSLFKCNLIKEGKWLVNKYNTFVDTSSLQLDML-EILLNLIKIESIVESLLK-FKKHWDLQFYFFNFGEVLANFLTLTFTQDAEEENQSTWIAYKQSTFKTQYQKAFLQVL-S-YPILLILHKRIIPNMAQ--PQSIMDFLTDCYDI-PAIPILALNSLYELMRKYNLEYPDFYTKLYSLLTPELLYIRYRSRFFRLCDLFLTSTHLSSNLVASFIKKLARLSLGASASGVVIVIPFIYNLLKRHPTCMIMLH-DPYDYNEKDKTNAVRSSLWELETLMSHYHPNIATLAKVFGEPFRK-HSYNMEDFLDWSYLTLLDSEKYK-TAA-LEYEEFD---WSL Plicr1 RKTNHPSQIQAL-EAEITTATSLNPLADLL-GLKAIYALYRVILITDGTWLWGRLDSYTEFLMLRVSAI-QILFSLLKHLSIVYGLLTWFSVHDDIRWFFLRAVPILANLLSILFP-TTTAELNAWWVLHALPSHRAVFTRAWLALLPR-LSALTVMHRGVLPHLTR--PVLVMDWVSASVDHGGTVGLLALNALFELMKGYNLDYPSFYTRLYAFLDRDVLHAKHRARFFRLAEVFLSSTHLPATILASFVKRLARLSLTAPPAAVVMVVPFVYNVLKRHPALMVMIHRDPFRAADANTTCAIDSSLWELHAQETHYHSAVSTLAKIFGEAFTK-PGYAMEDFLDHGYGTLLDTERIK-KPA-LGMDMRTE-LWAF Polpo -QKRESDLIRSL-EKEVLESDNTNKIIEII-AIQTIKSLERIQRLDSSKWILEIYQSYLKLLSIQIPTL-NSLFAMLTVQSLLEPLIRFI-QYHDV-QHSLMMTTMIENIFDLLVP-----AEWKFLVVTTISSYKQIFGKLWLAFL-S-LPVLLGLPDQVMPHLSN--PTLLMDFFSKSYDLGGIHSILALNGLFILIHKYNLEFPDFYKKLYSLFQPGIIYAKYRSKFFNLAELFLSSNYLPNYLVAAFLKRASYLCLITPPFGSLILLPLIFTLLQRHPNCHSLINNDPYLPMEADKCNALKSSLWEIQLLRQHYFPEIRKLATLFDAGLKG--TVSSSDFASSTYQSLFE-S----KP--LEFNNFEA-LWKF Pucgr2 TKTNSTKQIKET-EQQLKQTQDLNPIADLL-ERALIYALHRISLIRQGEWLKTQYSQYIDCLQIELDAL-TILINLVRAESLVKTLLRYLNFCDDLRFRFLKATFLCRNLLMYLMP-TREEELDQFWTLLSLRAHQKAFSDCWIAFLSR-QDILNLLHDQVIPHMID--PKILMDFLVDCLDYGGSISVLSLNALFTLISKHNLDYPDFYTRLYALLDSSIMHTRHRPRFFRMLEVFLSSTHLPVNIVASFVKKIARLSLFAPPAATITVVPFCYNLIKLHPTVMALLHRDPFKLDEPDKTDAIFSSAWELVGLRSHYLASISTLFKVFQESFDK-PKYDLEDFLDHSYSTLIDTEMIK-KPA-LSLFSISQ-MWKI Punst1 RKLTTGQKIKNL-EDELTRAGSLNPLADLF-DLKAMYALYRVLLASSGTWIWERLDGYVDFLALRTSSL-QILLSLQKHLSIVSGLLRWLSVHDDVRWFFLRSSTLLENLLSILFP-TDPAELNAWWVLHALPSHRAVFTRCWLALLPR-LTALNVMHRGVLPHLTR--AVLVMDWVGTCVDYGGTVGLLALNALWILIRDYNLDYPSFYTRLYAFLDRDVLHLKHRARFFRMTELFLSSTHLPATLLASFVKRLTRLSLSAPPAAVIMLVPFTYNILKRHPALMAMIHRDPFVADEPNATRALESSLWELHAHVRHYHPPAATLARVFEAPFTK-PAYATEDFLDHTYGTLFETERIK-KPV-VEAELPKE-TWVF Rhior3 -RKRS-QKIRAL-EASLS-DSNLNNIVEVF-KYAAIHSLNRSSFLMKGIWLRGQYIDFLVHVGLQLPAL-NILMNNIKSESIVKAIIKYLNIYDDLRHYFFKAAEIMSNVLSILMP-TEVSEIDEFWTLLQLGVHRRGFSECWLKLL-K-LPVLLILHKRILPHMSE--PKLLMDFLTDSYNIGGAVSLLALNGLFTLITEHNL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 KQKK--SRISQL-AALLPPAASLNPLADLV-QLTALHSIKAVALIKQGAWLNERWQDYLEATTVRLSAL-NALMSLVRTESVVRALLKWWDRCDDVRFFFLEAAALLPNTITVLMP-TVQSEINEWFCLLSLVAHRRVFQDCWFALL-S-LPVLIMLHRQVLPHLTE--PKRLEDWLVDCADKGGTVGILAMNGLFTLMQKHKLEYFGFYTKLYSLLDRSVLHVRYRPRFFRLLEIFMGSLNLSSNLVASFAKRLSRLALSASPAAIVTVVPFVYNLLKRHPSCMVLIHRDPYNADETDKTGALDSSLWELAALQKHYLASVSSLAKVFGEAMNK-QAYSMEDFLDHSYATLIETEKIT-NPA-LA-----A-LWSF Rozal11 ------KELKSL-ESSIISNKNLNNLTKLMEALFTSESCMRIHYHSQGLWLTDNFKNFVELMSIAFQAL----LSCIKLEWLFKTVIDYVSQFDDFRYYSFKLNGMLNNILTML-------EANLYF-SEVMSHQRQLYSNLWLKFLQK-IPILLRINDRVFPLMSN--PRLLIDYLTDTYNLGSGLSLLALNGLFVLITHYNLDYPDFYIKLYALLDHRIFHVKYRPRLFHLLEIFLSSPLLPSYLIAAFVKRMARLALFAPPGSILWLIPFIYNIMKKHESLLPMIQRDPYDHETLDKANAIKSSLWELTTFQNHFHPQVATMSKIFQEKMNK-PEYPLEDFNGISYIGMLEEEQMK-RPAALSYPAPT------ Sacce1 ------SEIKDI-AKRLTAAKQYNSIIKLINELFLVMSLFQIKLFSRGNWCRKVYEAFKTKLSLGLDSL-DVYLQLAELESLIIALWKYYTKFADIQYYFQSFNQLLGKWLALVCSSVDADE---IFVIENESKFKSNFEKNWLSLLN--GQILLILHKRIIPHFHT--PTKLMDFLTDSYNL-GVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFFRLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKHPNCMIMLHNDPFDVHESDLTHALDSSLWELASLMEHYHPNVATLAKIFAQPFKK-LSYNMEDFLDWNYDSLLNAEKLK-TPT-LEFEAFT--AW-- Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 KRKLQEKEVQRL-EQILTDAASLNPLADLV-DLKAIYALYRVLLINEGTWIREQMNRYVNVLTIRVSAL-QILFSLQKHLSIVSFLLKWFSENDDIRWFFLRAATLLINLLTILFP-TEQAELNSWWVLHSLPSHRAVFTRAWLTLLPR-LTALNVMHRGVLPHLTR--AVLVMDWIAACVDYGGSPGLLALNALFVLMKEYNLDYPFFYKRLYAFLDRDVLHLKHRARFFRMAEVFLSSTHLPATLLASFVKRLARLSLSAPPAAIVMVIPFTYNILKRHPKLMPMIHRDPFLPEESDQTNALASSLWELATHRQHYHAGVSTLAKIFSEAFTK-PSYAMEDFLDHTYGTLFETEKIK-KPA-LALDIGKD-LWVF Schpo1 -------MIKDL-ENEIYKSKNLNNILVLF-DYDAAAALCRVYLSRNGNWVCDNYINYTEKLALQVSFL-TMTMRLCKAESFCLELLSYLVPYDDVRFFFYKSKKVIFNTIRILLPSSSTSS----WA-------KRAFQESWLSAL-S-LPVLNVIHKRVIPFLQK--PNLLMDFLTDAYNSHHAVSLLALNGLFTLMISHNLDYPLFYPKLYALLDRNLLYLKTRSRFFRLLDLFLSSTHLPATLIASFIKRLARLALTAPPGAIAIVIPFIYNCLQRHPTCMQMLH-DSFDFDQPDLTGAIESSLWELSTLQNHYYSNIASLASIMSQKFTK-PRYELEDFLDHGYATMCDAEPLK-NPP-IEFEKRTK-SWI- Sorma KRKRSESQIQNL-ESQINESKHYNNIATLI-EYSAAEALCRVRLLASGKWLRDRLTDHHKAL-HATQAL-VLAMALLKAEAIISALLKFIDEYDDIRFYTFEIKDFLNTVFDFLVP-ESSEDLEDFYILRSLSQHKKRAQEAWLALF-N-LGVLDVMASSIAPWFIK--PELLMDFLTDCYNTGGSISLLALSGVFYLIQERNLDYPSFYQKLYSLLDTDILHSKYRSRFFRLLDTFLGSSHLPAVLVASFIKRLARLALNAPPSAIVVIVPWFYNLFKKHPLTTFMMHRDPFLPDEQDETHAIDSCLWEIVQLQSHYHPNVATIAKIISEQFTK-QSYNLEDFLDHSYGSLIDAEEVK-KPV-IEFMIPKS-LWDF Sphar ------VEAQKLTQTSTHVFNTL--FLRVVDAMFT--------------------KGFL---DVRYYTLKNLALTMKKLEDILSPIV--VEELDCF----LSLAGQQAN--TQS---TAADEAD----LTALAPHRKVFTVCWRALLRRALPVLLKLHTDIMPHMSN--PRLLIDFLTNAYDQGGVVSVLALDGLFVLMTQHNLDYPDFYVKLWRMFDHEIFVVKHRDRFLKLADTCLNSPLLPGYLVAAFLKRLGRLALRCPPSGAAYIMPLMFNMMQRHPNCMALIHRDPYIEDAGDNCQAIESSLWELDALFQHQVPSVAKFAEQFSDVFSK-SAFEVSDFLE-SDAAMIQDEKI--RDVPLEYQKPTSMGWTF Spipu1 KRKKGSAGVREL-AKECLETGKLNNIVTLL-ELASFVSIGHVTLLERGKWLRENRSVYVQLAAMQVAAL-ESLMSVVKDESVVEKCV--INTYDDVRYYFYKFGKILTTGFNIL-P-VEESELGTYLYVASAKEHKRVFSECWLAFL-R-QSVLLAMHKKIIPFLSK--PTLLIDFLVDSYDHGGAVSILALNGLFTLVTEHNLDYPDFYTKLYALFDKNLLHVKYRSRFLRLVDLFLSSSQLPSYLVAAFIKKMLRLALNAPPAAIVTIIPFVYNLLKRHPACLCLIHRDPYLVDEPNLCKALESSLWELQTLKSHYLHTISGLVRVFEEPIAKQPSYDLEDFLDHSYATLFESEKTV-APA-LA-----Q-ISDF Sporo1 KKKKEETRISHL-SSILPPAASLNPIADLI-DLLALHTLKGICLINAGAWLNERWRDYLARTTVRLSAL-NALMSLIRTESVVRAILKWWDRNDDVRYFFLEGAELLTNAITILMP-TASSELNDFFGLLSLVAHRRAFQDYCLAVL-A-LPLLIMLHRQILPHMTE--PRRLMDWLVDCAERGGTIAILALNGLFTLMQKHGLEYPDFYNKLYSLLDRSLLHVRYRPRFFRLLDIFLSSSHLPSALVASFAKRLARLALSASPAAIVTVVPLVYNLLKRHPSCMVMIHRDPFDPLEPSETNAIDSSLWELAALRDHYLASVSGLAQVFGEVMNK-QSYTMEDFLDHSYGTMLETEKIT-NPA-LA-----A-GWCR Stehi1 RRKITASKIAAL-ESTLTEAESLNPLADLL-LLKAIYAVYRILLLGPGAWIVDRVNEYADYLSLRTSAL-QILFSLLKHLSIISFLVTWLDVQDDIRWFFMRAQPLLQNLLSLLFP-TEAKELNSWWVLHSLPSHRAVFTRLWLTLLPQ-LRALNVMHRGVMPHLTR--AVMCMDWVGGCVDYGGVIGLLALNALFVLMKEYNLDYPSFYTRLYSFLDKDLLYLKHRARFFRLTELFLSSTHLPATLLASFVKRLARLSLSAPPSSIVIVIPFVYNVLKQHPALMVMIHRDPFDFAESNLTNALNSSLWEIQAHTRHYHAGVSTLAKIFGEAFTK-PNYPLEDFLDHTYGTLFDAEPIK-KPA-LRDPLVAF-LWTF Tapde11 KRK---DKITKL-ETELASGSSLNNIVHLL-DL-SQLSLYKVKLISLKSWLRERYSEYIKTL-IQLEAI-VLSLRLLKDDPLVSAIIDYLEQFEDLRFHFYKAEKAADNALSLLFP-EKDEDINKYWLVNTVSGHRKAFSGAWVAVL-R-FSILSIMHKRIIPRMPK--PQLLMDFLIDSYDAGGSTSLLALNGLFYLMQHHGLDYPKFFEKLYALFDENTMHVRHRSRFFRLADLFLNSTHVSANLLASFIKRMSRLSLTAPPAAIVIIIPLTYNLLKKHPSLMPLIHRDPFDAAEVDKTGALESSLWEMASLTSHYHPNVATLAKILGEQFTK-PSYNLEDFLDHSYTTMIDAEKLK-NIA-TSFEKPT--IIAY Thetr ------EEVQDDFAAQGVDAVAQMGMVRVF---DAVEDAAEA---ATGEWLGDRFEEYQALLCLKIPAL-DMLFKHLRRALVINAIIFLLGSADDLRAFVLQLAELPGFVIDRLIP-ATNDDMQEFILAVTAKDVRKAYERAWRKAVSA-QAILETFPETILANVLK--PLTWLDFLAHAYEQPGIVAVLALSGMHELITKYNLEYPQFYAKLYSLLTPAVLYAKYRARFFKLVHKFMRSTYLPHYLVAAFIKRLARLALSAPPQGALLAIQLIFNMMTNNPATVALVHRDPFDESENDKTNAQASSLWELQALEHHYSPTVARSARVFRTLEEE-KAYKLDSALNTSYATLIAVERVKVKAVALSHIRPRE----- Treme1 KLKSTAEQVKPL-ESQLLVKYNPNLLLSLL-ALKAIWALHRVVYIAEGVWTRDRLIEYVKLISLRTSAV-KLLFALLPPLSLLDAFFDYWAKYDDLRWIFFRTKRHLGNLLAQLLP-TLPEHINAFYIIYSIPSHQLVYTSLWETVL-T-LSVLVGLHKGILGHMKAERRVRVADWLGALVDKGGVEGMLAMNGLYVLMTKYNLDYPQFYKRLYGMLDNEVLHVKYRARFFRLLDTFLASPLLPATMIASFIKRLAQLSLFSPPAGIIMIVPFIYNLFKRHPGCMIMIQRDPYDPSEQSNSKAIDSSLWELAALQKHYLSSISTLSKVFGEVFTR-PEYDLEDFIDHGYTTLFNTEKLR-HPA-ISFEMENT-LWTF Trire2 KRKRASAKILLM-EQGILESKNYNDIATLQ-TILAAVALCRIRLLVQGGWLKDQFAQYKTLL-LAATAL-TLCMRLLKAEGIVQVLISYVEQYDDIRYYTFRVKAILDSVFALLVP-QSAEELEDFYILRTVTQHKRQGQDAWLAIL-S-IVILNVISTNIAPWFTK--PELLSDFLTSCYNTGGSMSLLALSGVFYLIQQRNLDYPSFYPKLYSLLDKDILHSKHRSRFFRLLDTFLGSTHLPAALVASFIKRLSRLALNAPPSAIATVIPWIYNLLRRHPTCTFMIHRDAFNPTEPNKTGAIDSCLWEVVQLQSHYHPNIATIAKIISEQFTK-QSYNMEDFLDHSYASLLDAEDIK-KPV-VEFQIPKK-LWDF Umbra1 KRKRGEQRIKVL-ESGLG-DSNLNNLVEIF-EIAAIHALHRVTLLLKGNWLRDNYNSYIKFLGLQKPAL-NILITLLKSESVVDAVLKYLNVYDDLRYYFFKTSDIIQNTFSILMP-TAGAEIDEFWTLVRLSVHKKALQTCWLAFM-K-MPTLLIMHKRIIPHMTD--PRLLMDFLTDSYNAGGATALLALNSLFTLIVDYNLDYPEFYHKLYRLLDANVLHLKYRSRFFRLLDLFLSSSHLPASLIAAFIKRMARLSLTAPPAGSVILIAMIYNLLKRHPSCMALIH-DVFDESNPDTCNALNSSLWELQTLAEHYYPNVATLAKIFTEQFTK-PSYNLEDFLDHTYGTFLDKEKRK-KPA-LAFEKPTK--WSL Ustma22 SKKAGSKQVKAL-QSALVSSSDLNPLSELL-TLRALVVLVKSSLSAEDDWLRMRWNETIELLSLRLEAL-QMLMDLQTTASLSLALIIGLHKYDDVRFATLRISHALAHTLALLIP-TTSDDLNQFLVLHSIGAQRSAFSAAWLDVL---LPVLVRLHAQILPHLTK--PTMLHDFLVSCLDSSGATALLALNAIFTLVTKHNLDYPHFYNRLYAMLDASVLHMKYRARFLRLLETFLSSTHLSSTLVASFVKRLSRLSLRAPPAAIASVVPFVYNLLKKHPRCLSMVHKDPFNAHESDLTHALDSSLWELASFEAHFLGSVTSLAHILAEPFTR-ERYSLDDFLDITYATLFETETLK-KPA-LAYSLPGT-LFSF Walse1 -------------------------------------------------------------------------MSLIRTESLVRSLLKWPGKCDDIRYFFFKTISLLANVLSILMP-TDQSEIDEFWV---LSAHRAMYSGVWLTLLKC-PTALVVLHQLVIPFLKPSERASLADWLSDCCDIGGVNALLALNSLWRLMRDHNLDYPDFYRRLYALCDRNVLHVLYRARFFRMLDLFLSSTHLPALLVAAFIKRLSRLSISASPAAIVMLIPFTYNLLKRHPGCMHLIHSDMYKVEETDLSNALDSSLWEMSTHQSHYHSSVNRMSQIFSQVFSK-PNFAMEEFLDHAYITMFDSERIK-NPA--------E-LFEF Zygro1 ------NEIKSS-AKLLTTSRNYNQVVQLVNDLFLVVALLQIKMFSRGEWCRQAYETFKSRLSLGLDSV-DIYMQLIEQESLIKALWKYYKSYGDIQYYFQSFNYLLGKWLATVCTNEGVDE---IFVVENESKFKTLLEKNWLLMVH--GETLLILHKRVIPHIHT--PTKFMDFLTDAYDL-GMVPVLALNGLFELMLRYNLDYPNFYQKLYGLITANLMHAKYRARFFRLMDTFLASTHLSAHLVASFIKRLSRLTLNAPPGAIVSVIPFVYNLLKKHPSCMIMLHNDPFDDKEPNRTRAMESSLWELASLTEHYHPNVATLAKIFSQPFRK-MNYNMEDFLDWSYDSLLAAERLK-VPT-LEYENFD--DW-- [Cluster2175.fasta_al_trimmed; alignment length = 61] Allma1 -VLWAQRATHLLVTIEVVVFSAKALDLLHEIDPKKWWPRLLSTKLKTDFAKWKDE--DESD Ashgo11 -VHWAQRSNYVLLTLVILEFSARSIDFFKEIDPEEYWPRLTKEKIKTDFDKWVDE--DEQE Aspfu1 -VTWAQRSNYLYVNIKTVSFTGETLDLYAEIDPEEYWPRLVKDTLKTDFDKWVDE--DEQD Aurde31 -VLWAQRSNIVYLTINLLNFKAKSIQFFDEIVPEEFWPRLTKDKVKTDFSKWVDE--DEQD Batde5 -VMWAQDRKSVFLTIRLLTFEAVVLDLFSTVKSDRFWPRLQKASLKTDFSKFVDDTFDDPE Botbo1 -ILWAQRSNLVYLTINVISFKATALDFYSEINAEEYWPRLTKTKIKTDFSKWVDE--DEQD Botci1 -VLWAQRSNFIYLTISVLTYSGYSLEFYAEIDESEFWPRLLKDALKTDFDKWVDE--DEQD Caeel -VLWAQRESLVYLTIEVLHFQGSSLEFFDEIDPAAWWPRLLQNKLKVDFGKWKDE--DEDD Canalb1 -VLWAQRSNIIYLTIQILIIDSKSIDFFKEIDPDEYWPRLTKEKIKTDFDKWVDE--DEQD Cangl -VAWAQRSNYLLITVSILDLEAQSIDFYKDIVPEEYWPRLTKEKIKTDFDKWVDE--DEQE Capow -VQWAQRRDKILLRVSIVSIDTVAIELYGEIDPAPYWPRLLKTALKVDFDKWKDE--DEAD Catan2 -SRWPHLSAFCFLTSGTFCFRKDNCPLHRPRSRRPWWPRLLADKLKVDFARWKDE--DEDD Cioin PTMWAQRPQVVYLTFKVVEFSGEDLEFFEEIDPEETWPRLTKEKLKVDFGKWKDE--DDTD CocheC53 -VVWAQRSNVIYLTIVALSFKGTSLEFYAEIDTEEYWPRLLKDSLKTDFDKWVDE--DEQD Coere1 -VLWADRTDRVYLTVALIDFSIDILDFFKPIKPEERWNKLVKGKLKVDFDHYQDE--DESE Conco1 -VLWAQRTNEIYLTIELLKFSGTSIEFFNEIDPEEYWPRLQKEKLKTDFDRWIDE--DEQD Conpu1 -VLWAQRSNVVFLTVNLISFKADALDLFAEVVPEEYWPRLTKEKIKTDFSKWVDE--DEQD Copci -VLWAQRSNIIYLTVNLIHFKAKAIDLFEEVDPEEYWPRLTKEKIKTDFDKWVDE--DEQD Croqu1 -ILWAQRSNIIYLTINVLSFSGTSLELFGELDLSEYWPRCVLYTLLLLFFFFF-------- CryneH991 -ITYAERSNIIYFTINAISFRAKALQLWGEIIPEEYWPRLTKEKVKTDFSKWVDE--DEQE Crypa2 -VLWAQRSNFVYLTITVLTFTGHSLELYAEIDEKAYWPRLLKEALRTDFDKWVDE--DEQT Debha1 -VLWAQRSNVIYMTIEVLKL---SLEFFDEIDTEEFWPRLTKEKIKTDFDKWVDE--DEQD Dekbr2 -VLWAQRSNIIFLKVRLLDITAKSIDFYAEINEEEYWPRLTKEKIRTDFEKWVDE--DEQE Dicdi -IKWAERPDFVYITIEAISFEGKGYDLFKEIDADPYWNFLLKDKVETDWTLWKDE--DEVE Dmel -VSWAQRNDLIYVIIDVFTFKGVNLNFLHEVDPEPYWSSLTTDKLKANFAKWRDES-DDEE Enthi ------------------------------------------------------------- Falba -VLWAQRNNLIYLTVDVIDFRVTGIEFFAQVNPDGFWDRLNKGSVKTDFARWVDE--DESD Fomme1 -VLWAQRSNIIYLTVNLISFDTKALKLFGEIDPEEFWPRLTGDKVKTDFSKWVDE--DEQE Fusgr1 -VLWAQRSNFIYLTISVLNFTGTSLELWGEIDPAEYWPRLLKDSLKTDFDKWVDE--DEQN Galma1 -VLWAQRSNFLYVTVNLISFKAQALEFYDEVVPEEYWPRLTKDKLKTDFSKWVDE--DEQA Ganpr1 -VLWAQNATELYVTVNVLSWEGGNMTLFKEVDPNGWWPRLTKDKIKTDFTRWKSED-DEED Gloin1 -VLWAQRSNELYITINVISFEGKSLEFHKDIKPEDYWPRLQKDKLKTDFSKWKDE--DEDE Hisca1 -VLWAQRSNLLYVHLAVISFSGYSLELYDDIDVDEYWPRFLKETLKTDFDKWVDE--DEQN Klula1 -VLWAQRSNNLFITINILEFSALSIDFYKPIDTEEYWPRLTKEKIKTDFDKWVDE--DEQE Lacbi2 -VLWAQRSNVIYVTVNLISFKAKTLDFYAEVVPEEYWPRLSKEKLKTDFSKWVDE--DEQD Lenti61 -VLWAQRSNILYVTVNLLSFKAKAINLFEEVVPEEYWPRLTKEKIKTDFSKWVDE--DEQD Malgl1 -ILWAQRSNVIMLTINVLHFESTVVEFYENIVPSEYWPRLTKDKVKTDFDKWVDE--DEQD Mellp23 -ILWAQRSNIIYLTINVFSFKGISLEFFDQLDLSEYWPRLTKDKVKTDFARWVDE--DEQE Mnele -VTWAQRKDRIFVTINVITFSGHNLELYGEVNKEEYWPRLLETKLKTDFNRWKDE--DETD Monbr -VKWAQREDAIFLTVSVFSFKSSAFDFHGEIVPEPYWPRLTKEKLKVDFDKWKDE--DDED Morel2 -VLWAQRANLVYVTVNLLEVTATSLEFNKPIVPENWWPRL--NKVKTDFARWKDE--DDED Mucci2 -VLWAQRADVLYLTVEILRFTGVGIEFYGNVDVEAWWPKLQKGNVKVDFQKWRDED-DEDE Mydma -VLWAQRKDRILVSVQILTFSGQSLEFFNNIVPEPFWPRLLKDKIKVDFSRWKDE--DESD Neucr2 -VRWAQRSNFIYLTISVLVFTGHSLEFYAEIDPAHYWPRLLKEPLKTDFDKWVDE--DEQH Orpsp11 -VLWAQRTDEIFITIDLLYFQGRSLKFYSKIDPEEYWPRLLEDKLKTDFGRWKDE--DDDD Pench1 -VTWAQRSNYLYVNIKAVSFKGASLDLFAEIDPEEFWPRLLESKLKTNFDKWVDE--DEQD Phybl2 -VLWAQRNDLLYLTVELFSFKGKGIEFFGEIDVEGFWPRLQKGSVKVDFTRWKDE--DDDE Picst3 ------------------------------------------------------------- Plicr1 -VLWAQRSNVIFLTINLISLKAKALTFFDEVVPEEFWPRLTKEKVKTDFSKWVDE--DEQD Polpo -VAWSERPDSVLIKIDATHFSFSGLDLFKEVVPE-YWNFLLANKVSVDWNTWVDE--DDLG Pucgr2 -ILWAQRSNIIYLTINVISFTGTSLELFGEIDLEEYWPRLTKDKVKTDFALWVDE--DEQN Punst1 -VLWAQRSNIIYLTINLLSFKAKALDFFGEVVPEEYWPRITKEKIKTDFSKWVDE--DEQT Rhior3 -VLWAQRANLLYLTVEILVFKGKGIEFFAPVNVEKYWPKIQKGNVKVDFQKWVDE--DEEE Rhoto1 -LLWAQRSNIIYLTINALKFEGKSLELFDEV--EEYWPRLLKEKIQTDWSKWVDE--DEQD Rozal11 -ILWAQRKNIVYVTVEILSVKAKSIKFYEPIKKEPYWPRLLNDKIKTDFTRWVDE--DEED Sacce1 -VAWAQRSNYVLITVSIIELKAQSIDLYKEIIPEEYWPRLTKEKIKTDFDKWVDE--DEQD Salro -VLWAQREDCVYLTVEVFSLKGKGIDLYGEIDPEPYWPQLTKEKLKVDFDKWKDE--DESD Schco3 -VLWAQRSNVLYVTINLISFKAKALDFFAEIVPEEYWPRLTKEKIKTDFSKWVDE--DEQD Schpo1 -VLWAQRSNVIYLTVLILVIDSKSIDFFKDIDVEEFWPRLTKEKLRTDFDRWVDE--DEQE Sorma -VLWAQRSNFIYLTIGVLVFTGHSLEFYAEIDPSSYWPRLLKESLKTDFDKWVDE--DEQH Sphar -VLWAPRSDRIYVTIELLIFSGKGLDLYGEIDPEEFWPRLINKGVKTDFKKWIDE--DEED Spipu1 -VLWAQRADELFVTINLLKFAGKAIDFYKEVDPEEYWPRLTKEKLKTDFSKWKDE--DEDD Sporo1 ------------------------------------------------------------- Stehi1 -ILWAQRSNVLFITINLINFKARSLAFFAPIKPDEYWPRLSKDKIKTDFSKWVDE--DEQD Tapde11 -VRWAQRSNIVYLTIVTMSVSGS-LDLYAEIEPKDFWPRLSASKVRTDFDKWVDE--DEQD Thetr -IKWAQRKDRVFLTIALLEFEAVAIEFFEAIDAESHWPRLTKNKLNTDWSKYVDS--DEED Treme1 -IIYAERCNIIYFTINAITFEADALELYDEIIPEEYWPRLTKEKIKTDFSKWVDE--DEQD Trire2 -VLWAQRSNFIYLTISVVTFTGTSLELYAEIDPAEYWPRLLKSSLKTDFDKWVDE--DEQN Umbra1 -VLWAQRADLLYVTVEVFSFKGTSLEFYGEIDPEGYWPRLLKSSLKTDFAKWRDE---DDE Ustma22 -ILWAQRSNVVMLTINVFSFNASVLDFFDEIDVEEYWPRLTKDKVKTDFDKWVDE--DEQD Walse1 -LRWAQRSNLLFITINLLEFEAKSIELFDKVQDKEYWPRLQKEKVTVDWSKWVDE--DEQE Zygro1 -VLWAQRSNYLLVTIAILEFSAKNIDFFKEVVPEEYWPRLTKEKIKTDFNKWVDE--DEQE [Cluster2180.fasta_al_trimmed; alignment length = 164] Allma1 KASAHDKAVFELKKQRDVLRKYQKQLATVLDREHAIAKQCLTAGDKR-RALLALRKKKYQEQLLAKTDQQLVTLEEMTSTLEYAVIEKEVMAGLQQGNAVLQALHQEM-SVEKVEAILDETAEAIAYQKEIEELLG--TLSE-EDEAEVERELMPSVPYAPLPA Ashgo11 KVTATDKAILQLKLAKDNLHRHAKRTDTLIENERSELRELAKSLKGSRRARLLLKRIHYQQRLLDQCSDQLINLENMVMTIEFKLVEKQFVEGLARGNEVLKKLNREF-S--GVEQLMDDVAEQVAYQEEIDQLLSN-GAGY-GLQDELDRELLPELPEKPMLA Aspfu1 AVLIKSRAILDLKNQRDKLRQHQKRITVLTDRETAIARECLARDDRR-RALLALRRKKYQETLLSKTDAQLEQLEHLTSQVEFSLVQKDVLFGLQQGTKVLQAINKEMGGIEAVEKLMGETEEARAYQEEISQMLA--GLSN-QDEDEVENELLPNVPRTAVPA Aurde31 KITAQDRAILDLKQQRDKVRQYQKRIQVILDREHEIAKECLRRGQKD-RALVALRRRKHQESLLSKTDGQLENLEQLVSTIEFSLVEVSVLHGLEQGNRVLKEIHKEM-NIESVERLLEETQEAQAYQREIDEMLM--SMTA-EEEEDVQRELLPSAPRTAIPA Batde5 KVTSKDKAILELKVQRDKLKQYEKKLQTVLDRELQVAKEQLRLKNHH-AARLALSKKKYQQSLLEKVSTQLLTLEQLTQSIEFALVEKQVVEGLKQGTQVLSDLNKEM-QLEDVEKLMDDSADAVAYQNQVGEMLS--QFSE-EDEADVMAEL----------- Botbo1 KITAQDRAILDLKLQRDKIRQYQKKITIVLDREHAIAKESLASGNKA-RALTALRRRKYQEGLLSKTDGQLEALENLVSTIEFSLVEKDVLFGLKQGNSVLKELHSEM-SLESVEKLMGETADAIAYQREIDEALM--SMTH-EEEESVQQELLPSVPRIALEA Botci1 -----------MKNQRDKLHQYQRRITVLTDRETAIAKEMLAKGDKK-RALLALRRKKYQESLLAKTDAQLEQLEKLTSSVEFALVQKDV---------------------------------------EVSDMLG--GMSN-QDEDEVEDELLPEVPRVAMLA Caeel PVSDQDNAILALKTQRDKMKQMIKRKENCLEKERQLAKQLIKDGRKD-RALLLLKKKRYQEKIIDQTLNHLSKIEQMVNDLEFAEVQQRVTDGLRQGNEALKKMNQLF-DIDEIDRIMEETKEAAEYQEEISNMLS--GLSN-TDVSDVEKELLPEAPKIALEA Canalb1 KITAQDRAIFQLKQQRDKLKQYQKRLNTIIEKQTELAKKAVLNKQPE-KAKFYLRSKKQQESVISTTFDQLNNLEKLIGTIEFKLIEKDVVYGLQQGNKVLQKLNNEM-QVEKIDALIDQLEDEKLKVDEVSELLGGVDLNR-SEEDEVDKEFLPKVPHEPIAI Cangl HITETDKAILQLKRSKDEIHKYTKKSDRLIAIEKDRLKQLIHDNPKDTKVRFLLKKIHYQEHLLQQASDQLINLENMVSTLEFKMVEKEFVSGLQTGNEILKKLNAEF-K--DVDKLMDDVQDQIEYQAEVDNALAN-SVGTNTFEDELDREL---LPEEALPA Capow RITPHDRAVLDLKKQRDNLKIYIHKIEAVLKREHELARTAVREGNKK-KALLLLKRKRFQETLIERAEGQIQNVEELTASIEFAVVEQQVLAGIKAGTETLTELNNQM-KLEDVERLMDDTQEAIAYQNEISEMLG--TLSE-VDEAAVLAELAPDVPTQAQLA Catan2 QSLSHDKAVFELKRQRDNLKKYQTQLNAVIARETAIARKCLAAGDKR-RALLALRKKKYQEQLLEKSDKQLFTLEEMASSIEYAQLEAKVLEGIQLGNKALADLHKET-SIEKVEKIMEETADAIAYQKEIDEMLG--TLSE-EDEEAVLAELLPAVPNERLKA Cioin RVTPQDRAILELKKQRDTLRTYQRKIENDQEVLKRLAKQCLKDGNKN-KAKLLLRKKKRQETLMTQTEQQIDNLEVMANDIEFAQLESNVFEGLKVGNESLKAMHKLM-SYEDVEKIMEETQEGIEYQRELDELLA--GVTQ-EDEESILAELLPDAPRTLLEA CocheC53 KISAQDKAILDMKNQRDKLRQYQKRITVLTDREKEIAKQCLAKGDTK-SAKLALRRKKYQESLLSKTDSQLAQLEVLTSDIEFALVQKDILYGLQQGTAVLKEIHKEMGGIENVEKLLGENEEARAYQEEISEMLA--NMSN-QDEDEVEDELLPDAPRAAEQA Coere1 KITAQDKAILDMKVQRDKLKQFQKKVEVVLNREDSLARELLQKGDKS-RALLALRRRKYQQQMINKTDMQLFNLQNLVEQIEFSLVQKDVLFGLEQGNKVLSQLNSEM-RIEDVERLADNTAEAIAFQKEVSNILN--AMSA-EDDEAVLEDLIPQAPNEPLLA Conco1 KISSKDKVVLDLKIQRDKLKQYSKKIDLVIENETKIAKKLISEGKKD-KALLALKKKKYQEKLLDDLGQQLFNLEEMTSTIEFTLVEQQVLEGLKKGNEVLNQLQKET-PLDQVEKLMEDTLEAIEYQREIEEILS--TLPI-EDQEALLEELLPNVPRKPVAI Conpu1 KITAQDRAVLDLKLQRDKLRQYQKQIQGILDREYEIARLHLAAGHKE-RATVALRRRKYQQGLLLKTDGQLENLEQLVSTIEFSMIEVSVLHGLKQGNDVLKQIHKEM-SIESVEKLMEETAEAREYQQEIGEILS--NLTL-DEEDAVQAELLRC--RVRIPA Copci KITAQDRAILE---EINYANTRRRQIQAVLDREHEIARKHLAAGQKD-RALIALRQRKYQQSLLLKTDAQLENLEQLVSTIEFSLIEVSVLHGLKQGTEVLKDIHREM-NIESVEKLLEESAEAREYQR-VG---S--SACL---------------------- Croqu1 RITPQDRAILDMKLQRDRLKQYQKKIEVIANQECKIAKDALANGNKS-KALLALRRKKYQETLLSKTDLQLETLQNLVSTVEFTLIEKDVLYGLKQGNEVLKEIHKEM-NLDSVEKLMSDTAEAVAYQREIDGLMM--SMSA-DEEEDVQRELLPDVPQEAMLA CryneH991 KITTQDRAILDLKLQRDKLKQYQKRLQVILDREHEIAREALIAGNKK-RALTALRQRKYQEQLLSKTDSQLVTLQELVSTIEFTQIQNTVLHGLEMGSHVLGELQKEM-SLERVDRLMDQTREGVEYQREIDEALM--SMSP-EEEEAVQEELLPNVPRVAVAA Crypa2 RVTAQDKAILDLKIQRDKLHQYQRRITGLTDRETDIAKQMLAKGDKK-RALLALRRKKYQESLLAKTDAQLEQLEKLTANVEFAQIQKDVVFGLQQGTKVLKEIHAEMGGIEHVEKLMGETADAIAYQNEVSEMLG--GISN-QDEDEVEDELLPKVPRQAVLA Debha1 KITLQDRAIFLLKQQRDKLKQYQRKLNTIIERQNKLAKEAIIKKDNA-RAKVYLRSKKQQQTTITKTYEQLDNLETLIGTIEFKLIEKDVMYGLEQGNEVLKTLNSEM-SVDKIDKVLDGLEDERLKVDEVLDMLGMGSLSN-GEEHEVDEELMPAVPNEPIAA Dekbr2 KITSQDKAILQLKIQRDKLRKTSIKVQTVIKRENEIARQCVRKGDKR-RALLALKKRKYQENLLDTVGKQSDSLETLINTIEFKLIEKDVVYGLQEGNKVLKQLNTEL-SVDKVDKIMDETAEGVSYQEELSERLG--EMPR-ALDAEVDEELLPAAPPQAVPA Dicdi KISKTDRAVLNLKIQRDKLKNYQTQV-----LEIAIAKECSKAGKKN-QALLALKKKKYQEKMLDESFANLQNIEELIANVEQAEIQVRIFESLKQGNESLKEIQKEM-SLEDVENLMEETAEAIQYQNDISEALS--GFSK-EEEDDLLNELYPKVPSIGELS Dmel RITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQGRKD-RAKLLLRKKKYQESLLTNADKQLENLEKLAADIEFAQVEMKVLDGLKAGNAALKKVHEML-DIDEVERIMDETREGIEKQQEIDAILT--DLTT-QDEEDVLAELLPDVPKVLVEA Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba TITEHDRAVLNLKNQRDRLQKYERQLEALTAKEIEAAKTLLQQGDKK-RALMCMKRKKLRERDLANITGLLDNVHHTISTLEFAKVQVDVVSSLKDGSEALKRLNDLM-NIDKVDLIMADTAEAIAYQNGATNAR----------------------P------ Fomme1 KITQQDKAILDF------------SIQTVLDREQEIARQHLRAGHKD-RALVALRQRKYQESLLVKTDNQLESLEQLVSTIEFSLVQVSVLHGLKQGNDVLKEIHREM-NPESVERLLEETAEAQAYQREIDEMLS--NLTL-DEESAVQEELLPEAPRVALEA Fusgr1 KVTAQDK-----------LHQYQRKITVLTDKETDIARQMLAKGDKK-RALLALRRKKYQESLLTKTDAQLAQLEKLTSDVEFALIQKDVVFGLQQGTKVLKEIHTEMGGIENVEKLMGETADAIAYQQEVSDLLG--GMTN-QDEQEVEDELLPDVPQPAMLA Galma1 KITPQDRAILDLKLQRDKLKQYQKKIQAVLDREQAIAKAQIAAGQKD-RALIALRRRKYQQSLLTKTDDQLENLEQLVSTIEFSLVEVSVLHGLKQGNEVLKEIHKEM-NIESVEKLLEETAEAREYQKEIGDMLS--NLTL-DDEEAVQKELFPVVPRVLVAG Ganpr1 KISKVDEAMWELKKQRDKLKDYKKQLENVFEKETQVAKTCLAKGDRR-RAMLALRKKKYQETLIQRTDEQLFMLEKMASTIQYKEVEKKFLDSLAQGNEVLKRLNAET-SVEKVDALMQDTADAIAYQKEVSDAIG--SLTD-RDEADVEAEL----------- Gloin1 RITSQDRAILDLKVQRDKLKQYQKKLQLVADRETQIAKEALLKNNKR-GALLALKKKKYQEQLLSKSDAQLLNLEQLTQTIEFTLVEKDVFEGLKQGNLILNEIHKET-PIEKVEKLMEDTADAIAYQNEISEALS--GLTS-EDEEEILAELLDKLPLEAALE Hisca1 KISAQDKAILDLKNQRDKLHQYQKRITALTDRETQIARECLARNDRS-RALLALRRKKYQQSLLAKTDAQLDQLERLTGSVEFALVQKDVLFGLSQGTKVLQTIHKEMGGLEAVEKLMGDTEEARAYQEEVSRMLG--AMSN-QDEDEVEDELLPDAPRAAVPM Klula1 KVTESDKAMLQLKMAKDELHRYSRRTENLIGVERAELRTLCIKLKGDNRARLLLKRIHYQERLLEQCSDQIINLETMVQSIEFKLIEKKFIDGLQKGNQLLKKLNVEL-NLEKVESIMDTAAEQIEIQREIDDALSN-AVGS-TINDEVDRELLDQLPEEPLLA Lacbi2 KITPQDHAILDLKLQRDKLRQYQKKIQVVLDREHAIAKTHISTGQKD-RAIIALRRRKYQQGLLLKTDGQLENLEQLVSTIEFSLVEVSVLHGLKQGNEVLKEIHREM-NVESVEKLLEETTEAREYQREIGEMLS--NLTL-DEEDAVQLELLTCTLRFAVHS Lenti61 KVTKQDRAILDLKLQRDKVRQYQKKIQVVLDREHEIAKQQLAAGNKD-RALVALRKRKYQEGLLAKTDAQLENLEKLVSTIEFSLVEVSVLHGLQQGNEVLKEIHKEL-NVENVERILEETQEAREYQREVDEMLA--NLTL-EDEEAVQAELLPSVPRVPVAA Malgl1 -----D-------------------LQVVLEREHEVAKIAIREGKKE-RARLALRQRAYQNGLISKTDQQLATLQELVSNIEFAQLEQSIIYGLTQGNQVLKQIHRET-SLERVEHLMEETAESQTYQREIDQMLS--SLSA-DEQQAVEDELLPSVPRQAILE Mellp23 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KITAHDRAILDLKVQRDKLRQYNKRLEGVVEKELRLAKGHLAKGEKQ-RALLALRRKKFQESLLEKTVLQMTNLDELTMSIEQAMVEKQVFAGLAAGNQVLKELHKEM-SLADVEKLMDETADSIAYQNEIDELLS--TLSV-ADEEDIERELLPNTPRET--- Mucci2 KVTSQDRAVLDLKVQRDKLKRYQKNLNVVIDKEVEAAKLALQQGNKQ-KALLALKKKKYQVQLLEKTDQQLMNLEELTHSIEYALVEKQILEGLKHGNDVLNEIHKET-SVEAVEKLMDDTADAIAYQNEIDEMLS--GISA-EDEEEIMKELLPSVPKQAMLA Mydma RITEQDKAILSLKQQRDKLKQYQKKINLNLEKEKEIAKKLLMDGKKE-KAKLMLKKKRYQENLLQKTDSQLENIDKMVHEVEFSLIQIKVAEGLKQGNEALKKLHEMM-SLEDVEKIMDDTKEAVEYQNEINALIG--GLSE-EDENEILAELLPSVPETPVAA Neucr2 RVTAQDKAILDLKTQRDKLHQYQRKITVLTDRETAIARQMLAKGDKQ-RALLALRRKKYQETLLQKTDAQLEQLEKLTSSVEFALIQKDVFFGLQQGTKVLKEIHAEMGGLDHVEKMMGETAEEIAYQQEVSEMLG--GISN-QDEDEVEEELLPNVPRQAMLA Orpsp11 -------------------------IQAVLDREYEIAKINLKNGDKK-KALLALKKKKYQEQLIEKVDAQLLNIEELTNSIEYAVVEKEVLDGLKNGNEILKQLNNEM-NIEKVEELMNETAEAVAYQNEISELLS--GLTV-EDEEAIENELLINLY------ Pench1 KISAQDRAILDLKNQRDRLHQYQRRITVLTDRETEIAKECLARDDRR-RALLALRRKKYQESLLAKTDGQLAQLEQLTGQVEFALVQKDVLFGLQQGTKVLQTINKEMGGIEGVERLMGETEDARAYQEEVSQMLA--GLTN-QDEDEVEDELLPSPPRTALPA Phybl2 KVTAQDKAILDLKIQRDKLKQYQKKVNVVLEREVSEARKALGQGNKK-KALLALKKKKYQEQLLEKTEQQLMNLEELTNTIEFALVEKQVMEGLKGGNAILKEIHKEM-SLEDVERLMDDTEDAIAYQNELDEMLS--GMTA-EDEEDIMRELLPEVPKQAMLA Picst3 KITAQDRAIFQLKQQRDKLKDYQKRLTFVIEKQTNLAREAVKNGQND-KAKFYLRLKKQQETTIVKTCEQLDNLEGLIGTIEFKLIEKDVIYGLEQGNLVLKKLNNEM-KIDKIDKILDDLEEERIKVDEVSDALGMGSLSK-LEEFEVDEEFLPEVPNEPIAS Plicr1 KITAQDRAILDLKLQRDKLKQYQKKLQVILDREHDIARAHLAAGQKD-RAVIALRRRKYQQGLLLKTDGQLENLEQLVSTIEFSLVEVSVLHGLKQGNEVLKEIHKEM-NVETVEKLLDETLEAREYQREIGEMLS--NLSL-DEEDAVQAELLPSPPRVPVAA Polpo QISDKDKAVLELKIQRDKLKQYQIKINLVIQRETEIARECAKNNKKQ-QAILALKKRKYQEKLLEDTDQNLMNIQEMVSTIEQAHIQIKIAEQLKQGNNALKELHKEM-SLEEIENIMSDTQDAVDYQNEISEALS--GFTQ-EEEDELMAELFPEVPRVPEMA Pucgr2 RITNQDRAILDMKLQRDKLKQYQKKIETVLKLEEEVAKQCLLANNKP-KALIALRKKKFQENLLSKTDQQLETLQNLVSSVEFSLIEKDVLFGLNQGNQILKEIHKEL-NIENVEKLMSETADSIAYQNEIGELLM--SMTN-EEEEEVHKELLPDVPREAIPA Punst1 RITAQDKAILDLKLQRDKLKLYQRKIQAILDREQEIARQHLLAGEKD-RALIALRRRKYQQSLLTKTDAQLETLEQLVSNIEFSLVEVSVLHGLKQGNAVLKELHKEM-SVESVEKLLDETQEARAYQQEIGDMLA--NLTL-DEEDAVQAELLIS---LSIAG Rhior3 ----------------------------------------------------------------------------MCVT-------------IKIASELPKVPDQKL-----------------------------------PDSGEVNNE-LPEVPKQAMLA Rhoto1 KITPQDRSILDLKLQRDKLKQYQRRIEVVLAREREIAAESLKTGNKQ-RALTALRQKKYQETLLSQTDAQLETLQKLVQSIEFSLVEKDVLFGLKQGNDVLKQLNKEM-DLATVEKLMDDTREGIAYQEEVSALLS--SMSA-QDEEDVQAELLPEAPRQAIAA Rozal11 MIIACDRAV---------------------------ALECLRVNDRE-RARLALRKKKYDETLLQRTGEQLATLEELYKA-----VEKSVVEGLEKGRMVLEALNREM-SVERVEMIMDDTRDAIEYQKEVSDMLG--NLSS-EDEEEIMKELLVPAPEVLLPA Sacce1 HITKTDRAILEVKRSKDEIHKFTRRTDNLILVEKSQLKDLIRKNPENMKVRFLLKRIHYQEHLLQQASDQLINLENMVSTLEFKMVEKQFINGLKNGNEILKKLNKEF-S--NVDELMDDVQDQIAYQNEINETLSR-SVGTSNYEDDLDKEL--NMPKEPLAL Salro KITEQDRAQLKLKQQRDRVKQYRKKIVIMIDKEKQQAKTFIKAGEKS-KALLILKKKKYQEKLLENTLTQIENLEHMISQIEFAEVEVKVLDGLKQGNQALEALKKEL-SVEDVEEVMADAQELQQWANDISEIAG--TLDD-LDDDELFAEFVPAVPPELVPA Schco3 KITAQDKAILDLKLQRDKLRQYQKKIQTILDREHAIAKTHLANGQKD-RAIIALRRRKYQESLLVKTDGQLENLEQLVSTIEFSLVEVSVLHGLKQGNEVLKEIHKEM-NIESVEKLLDETAEARAYQQEISDMLA--NLTA-EDEDAVQNELLPSAPRVAVPG Schpo1 KINDKDRSILSIKEQRDKLLRYSKRLEKIEQLEIDIARKCLRDSDKR-GALRALKAKKLYSGLITQTYGQLGNIEQLLSTIEFTLIQKDVMFGLQEGTNLIRQLQADM-PLERVGRICNDRDEAMSYVDEVNDMLQ--GMSR-DQEDEIQEELLPSVPKDPVLG Sorma RVTAQDKAILDLKTQRDKLHQYQRKITVLTDRETAIARQMLTKGDKQ-RALLALRRKKYQESLLQKTDAQLEQLEKLTSSVEFALIQKDVFFGLQQGTKVLKEIHTEMGGLEHVEKMMGETAEEIAYQQEVSEMLG--GISN-QDEDEVEEELLPNVPRTAMLA Sphar NLTLTTNVLPTL------------QLSGSVEKEQELAKKALASGDRK-RALLFLKKKKYQQSLLDKAENQHANIEEMIGNVEFASIQKEVFERLKAGKEVLEAINKEI-SLDDVDKLMEENEEAIAYQDQVAQALG--TLSS-QDEEDVLAELFPAVPRVAEAN Spipu1 KITSKDKAILDLKIQRDKLRQYQKKIQVILSREVEVAKHHLRSGDQG-RALLALKKKKYQEHLLAETDQQLLNLEQLTSQIEFALVEQDVVKGLQQGNEILKQIHQEM-SLDAVQKLMDDTADAIAYQAEIDELIS--GISP-EDEEEIMAQLLPDVPLMA--- Sporo1 -LTTSPRLVCSLKLQRDKLKQYQKRIEVVLKREREIAAESLRAGNKQ-RALIALRQKKYQEGLLSQTDSQLETLQKLVQSIEFSLVEKDVLFGLQQGSEVLKQLNKEL-DINKVEKLMDETREGIAYQEEVSALLS--SISA-QDEEEVLAELLPQVPRQAIAA Stehi1 KITAQDKAILDLKLQRDKLRQYQKKLQAVLDREQEIAKQHLAKGQKD-RALVALRRRKYQETLLVKTDGQLENLEQLVSTIEFSLVEVSVLHGLKQGNEVLKEIHKEM-NLDSVEKLMEETAEARAYQQEIGDMLA--NLSL-DEEDAVQEELLPSAPRVPVAA Tapde11 KVSNHDRAILEMKLQRDKLKQYQKRIQLVSDRETEVARQCLARGDKK-RALLALRQKKYQEGLLDKTDDQLATLEQLTSNIEFSLVEKDVLYGLAQGNKVLKDIHKEL-SIDKVERILDEGADAVAYQEEISQLIG--QISN-ADEDEVLEELFPEAPRVAQLA Thetr EITAHDRAVLDLKNQRDKLGRQKKKMAANMDRLQGMAMELVRSKQKT-KALLVLKKKKVIVSNMEKIESMLDNVQELVDSLEFAARQAEVFDSLRTGADALKDINAQM-DIDEVERIMDDTQEAIEYQNELSNALA--GLQP-GEEEDLEAELMPSVPRVAMEA Treme1 KISSHDRAVLDLKLQRDKMKQYQKRLQVILDREQDIAKEALKVGNKKSRALTALRQRKYQEQLLSRTDAQLQTLQELVSTIEFTQIQSTVMHGLSVGNEVLKQLHAEM-SLDKVERLMDQTREGIEYQREIDETLI--SMSP-EEEEAVQAELLPSVPRGD--- Trire2 KITDQDKAILDMKIQRDRLHQYQRRITILTDKETDIAKQMLAKGDKK-RALLALRRKKYQETLLSKTDAQLEQLEKLTASVEFAQIQKDVVFGLQQGTKVLSEIHAEMGGIEHVEKLMGETAEAIAYQNEISEMLG--TITA-QDEEEVEDELLPTVPRQAMLA Umbra1 KITDQDKAILDLKVQRDKLKQYHKKLQIVADKEVEIAKQSLAQGNKK-KALVSLKKKKYQEQLLEKTDAQLMNLEELTNSIEFALVEKQVLDGLQKGNEVLKEIHKEM-SVEAVQKLMDDTADAIEYQN---------------------------VS------ Ustma22 KITPHDRAVLDLKLQRDRIKQYQKKIQVVLDREHEIARQCLLRGDKT-KALTALRKRKYQESLIQKTDSQLETLEGLVSSIEFSQIQQSVMLGLQQGNAVLKEIHKEM-NPESVERLLEETAEAQAYQREIDDMLA--TMTA-EEEDAVQSELLPTAPRQAILA Walse1 KQSKVDEILLDNKLQRDKLNKYKSSLDRLIALNLDLAKNALKMNDVQAKKFIQIKNQNIHKQ--EEIEKQLASLTGLISSIETQVAQQRLVEQLEKGNKLLTGLHKEM-SISQVHNIVDNLSDQIEYQNEISNLII-------THDPDLDQE------------ Zygro1 KITKNDRAILQLKRSKDEIHKFAKRTDNLIASERVRLKTMIQEDPKNPKIRFLLKRIHYQNHLLEQAGDQLINLENLVSTLEFKLVELQFVKGLEHGNEILSKLNKEF-K--GADQLMDNVQSQTSYQNEINDVLAR-SVGVDDFEEELDKEL---MPERALA- [Cluster2181.fasta_al_trimmed; alignment length = 117] Allma1 DTYLFNDLFTIADVDKDGQRFDRVSRLTATSA-NYNADLILDFNNELYPLDKVTLMLTTSLALSDEYDYVCHGKCYKMEDSQVSVYISFGGLLLRLKAEFKDLAAFKGENVYLLMRK Ashgo11 -STLFDDIFTIQEVDQ--GRYNKVSRIEAISTSQDTCKLTLDVNTELFPLQQLTVMLATTLNLADDFDYVTYGTAYKFEEDMLAVYYSFGGLLMRLEGNYRLLSNF--ENVYLLCRR Aspfu1 DPLLFDDTFTITAINS--QKYDRVSRLSCTSS-DSVTTFTLDINSELYPCESVSMALASTLSLANDYDYVCHGKVYRFEEGNMAVFVSFGGLLLYLEGPYKKLAPL--DYVYLLLKK Aurde31 SSIVFDDLFKIQEVDQGGKKFDRVSRLAAHSS-NLDMHLTLDYNSEIFPLQSFTMALATSLGLDNEYEYVMYGKVYKFDEENVTAYASFGGLLMALSGSFRHMQGILGDPIYLLIRR Batde5 ---LFQDIFEITDIDPHGKKFDRVSRIVATSE-NIDMGVTLDINTEIYPLDKFTLALASTLALADDYDYVMYGKVYKYED--VSVYASFGGLLMCLAGDFRQLQNLVGQYIYLLMRK Botbo1 ASVLFDDLFTVDAIDKDGKKFDRVSRLSATSS-NFGMSLTLDYNVELYPLESFTFALASSLRLEEDYEYVMFGKVYKFDEEVVTAYASFGGLLMALTGSYRHMQRIIGENVYLLMRR Botci1 DAQLFDEHFTVNELDH--KKYVRVGRIKATSTVDHSVSMLLDINTELFPLDNIRVVLATSLNLADMFDYVCHGKIYKFEDDLIKAYISFGGLLMGLEGPYKKLTPL--DYVYLLVKK Caeel -GIIFDDMFKVKSVDPDGKKFDRVSRYFCDAE-SFKMELIIDINSQIYPLDKVRLVLATTLRRIKQYEYVMYGKVYRLEDGKLAAYASFGGLLMRLKGEAINLHGFVDMNLYLLMKK Canalb1 -GILFEDMFIVDSTDP--GRYNKVCRITGHSSTSKDITITLDINKELFPVDSLTITLASSL-LADDYDYVMYGTVYKFEEDKMAVYISFGGLLMRLEGGYRSLSNL--ENAYILIRH Cangl -TTLFDDIFTISEVDP--GRYNNVCRIEAGSTTQEQCKLTLDINTNLFPVEQLTVTVASSLDLADDYDYVMHGTAYKFEEDVIAVYYSFGGLLMRLEGNYRNLNNL--ETAYLLIRR Capow SGVLFEDIFEVKDINRDGKKFDRVSRLECQSE-NYDMALVLDINSQIYQLEKFSLMLASTLNRADNFEYVMHGKIYRCDEDKLAVYVSFGGLLMRIKGDARNLDKLLDDNIYLLIRR Catan2 DIILFSDLFTISAVDADGKRFDRVSRLKATSD-NYNADVTLDFNNELYPLEKFTLTLATP--LSDEYEYVCNGRCYKFEENLVTVYISFGGMLLGLKSKPQDLNQFKGEHVVLLMRK Cioin TGLLFEDIFDIKDVDPEGKKFDRVSRLHCDSE-SFKMELILDINTQLYPVDKFRLVLATTLSRADQFEYVMYGKVYRIEGSKLSAYVSFGGLLMRLQGDANNLHGMVDQNLYLLLKK CocheC53 DAQVFEETFNITSINN--EKYDRVSRIYGTST-DSQITMTLDINHELFPVESITLVLATTLALADMYDYVCYGKNYRME-DTIKYFASFGGLLLYMEGPHRKLSGL--DDIYMLVKH Coere1 ENILFSDTFAVKDMDKGGKKFDRISRLDGRSQ-THDMSLILDVNTELYPVDKFKLTLSSSLSLADDYDYVMFGRVYRYDN--VSAFVSFGGLLMCLEGDIRHLQNFVGDTIYLLMRK Conco1 NNFIYKELFQVSTIDKDLKKFQRVTRFYFKHQKVEDYQITIDIASDLYSPSLVDVYMAFSLKVINRFDYIMHGKCYKFQPDTVSTYFSFGGLLMEIKGPFEKLTQFIGEYVYLLIRK Conpu1 SNIVFDDIFTINSIDKEGKKFDRVSRLFAHSK-NYDMDMTLDYNTELYPLQSFAMALASSLSLEEDYDYVMYGKVYKFDGEIVTAYASFGGLLLSLTGSSRHMTNILGDPVYILLRK Copci SNILFDDIFTISDIDKEGKKFDRVSRLYAHSK-NYDMDLTLDYNVELFPLQSFALALASSLTLDDDYEYVMYGKVYKFDGEIVTAYASFGGLLMSLTGSFRHMTSILGDPVFILLRR Croqu1 SSLLFDDLFTLTALDKEGKKFDRVSRLTAVSS-NHGMNLTLDFNLELYPLDCFALALSSSLTLADEYEYVMYGKLYKFDTDTVTCYISFGGLLMALSGDYRYATTLTNVYRFMVILR CryneH991 SNIIFDDRFTVDTVDKDGKKFDRVSRITATSH-SLSMSLTLDIANELYPVETFTLTLARSLVLAEDYDYVMYGKIYKFDDAQTTAYFSFGGLLMALRGSYRHLAGVVGENVYLLMRK Crypa2 DAVLYEEPFVITAKDH--KKYDRAARLTAISH-DNLTKLELDINTELLPIENIEVCVASTLSLADGYDYVCHGKIYKFEDKTLKVYASFGGLLMALEGPDAKLTPL--DSVYLLIKT Debha1 -GILFEDMFNVDSVDS--ARYNKVSRITGQSSTSQDIKITLDINSELFPVDSLTIMLASSL-LADDYDYVMYGTVYKFEEDKMSVYISFGGLLMCLEGGYRSLSNL--ENAYILIRH Dekbr2 -STLFDDIFDVESVDP--GRYTKVCRVIAKSTTSPDTKITIDINTELFPVDTLTITLAKSLSLMDDYDYVMYGTVYKFEEDKISLYCSFGGLLMCLEGNYRTLSSL--ENLYILMRH Dicdi TSILFEDTFEVKEIDPDGKKFDRVSRFVCYSE-NYEMDLQIDIATHIYPLERFKMVLASSLNLADKYDYVMYGKIFKYQKSKVSVFASFGGLLVLLQGDPRYLPGILDARIYLLIKK Dmel -GVLFEDIFNVKDMDPEGKKFDRVSRLHCESE-SFKMDLILDINSWLYPMDKFRLVLATTLRRADSFEYVMYGKIYRIEGSRLSAYVSFGGLLMRLQGDANNLHGFVDQHMYLLMKR Enthi ----VSGTFKVIAKDIGGKIFEGVSRFKLEGE---DLTVFVDINTDLFPLDRIKLDLTKTLNKMDDFDYVMSGMVFKFVEDNLSVIASFGGLLLMLYGKPEKLSAYMKDQVYLLIRK Falba SAHQFEDYFEVFEQDPGGKPFDRVTRIVANGE-NTAGEITLDVHSDLFPLNKFYLVLSKTLSLADNFEYVMHGRVYRSVPRRIILFISFGGLLMCLKVAPRHLNNLLGEDVYLLMRR Fomme1 SNIVFDDLFTINAIDKDGKKFDRVSRLFAHSS-NYDMDLTLDYNTELYPLESFSLVLASSLVLEEDYEYVMYGRVYKFDGEIVTAYLSFGGLLMSLTGSYRHMTGILGEPVYLLMRR Fusgr1 DATLFEESFTVMEYDQ--SKYDRVARIHCTSA-DSQTIMSLDINIELFPCDSLHVVLTTTLAIADLYDYVCHGKIYKFEENTINAYVSFGGLLMSLQGPVKKLTPL--DNVYLLVKK Galma1 SSIVFDDIFTINAIDKEGKKFDRVSRLYAHSK-NYDMDLTLDYNLELFPLQNFALALASSLALEDDYDYVMYGKIYKFDGEIVTAYISFGGLLMSLTGSFRHMTSILGDPVYLLMRK Ganpr1 GAVFLRETLHVDALDKDGKKFDRVSRISGRTK-DSDLDVSIDVNTEIYPVDDYSLALAHSLVLADDYDYVMGGRVFKFEDDRVSLLISYGGLLMSIEGPPRYFSGVKGQTVYLMMRK Gloin1 NYILFTDTFAINDMDKEGKKFDRVSRFTGRGE-NLEMELTIDINTELCSLDKVMLMLTTSLSLSDDFEYVMYGKVYKYDESKVAVYVSFGGLLMSLEGDFRHVQNIVGQNVYMLMKH Hisca1 DPVLFEDTFTITAINA--QKYDRVARINCTSS-DNLTTFTLDVNTELYPVESLSLALASTLALANDYDYVCHGKVYRFEEENMSVFVSFGRSFALLGGPI----------------- Klula1 -SALFDDVFTVQEVDT--GRYNKVSRIEAQSTSQESCKLTLDINSELFPIDQLAVMITTSLQLADDYDYVMYGTAYKFEEDLLAVYYSFGGLLMRLEGNYRLLNNL--ENAYLLCRK Lacbi2 ANIVFDDIFTISDIDKEGKKFDRVSRLYAHSK-NYDMDLTLDYNVELFPLQSFALALASSLALEDDYEYVMYGKVYKFDGEIVTAYASFGGLLMSLTGSFRHMTSILGDPVYLLMRR Lenti61 --------------------------------------------------------------------------------------------------------------------- Malgl1 ---LFDTQFVVKDIDPDGKKFDRVSRVIASSP-TLDMTLSLDIATDIYPVQQLAFLLVSSLRLAKGFDYVMYGKIFKYDEEQVTVYGSFGGLLMALTGSFRHLSKIVGSNVYLLMR- Mellp23 ---LFDDLFTLTDLDKEGKKFDRVSRLKAISS-NHSMNLTLDFNIELYPLDCFALALSSSLTLADEYDYVMYGKLYKFDTDTVTCYISFGGLLMALSGDYRHLDQLVGQMVFLLMRR Mnele -GVLFEDIFDVKDVDPNGKQFDRVSRLFCESE-SFKMDLILDVNTMIYPVDKFRLLLATTLQRADTFEYVMYGRIYRIEGAILSAYISYGGLLMRLKGAANNLHGMVGQTVYLLMKK Monbr STVLFEDVFTVRDKDPHGKRFDRVSRVICEGM-SFNIELILDLNTQLYPVDRFTLCLASTLSRADNFDYVMHGTIYRIED-GQQLYVESSASV------SICMLPP--APCFLALQA Morel2 DNVLFSDIFDIKDVDGAGKKFDKVSRINARSE-NYEMELTLDINNELYPLEKFSLVLATSLSLADDYEYVMYGKVYKYDESSV--YISFGGLLMCLEGDFRHLQSILGENLYLLMRK Mucci2 DNILFQDIFDIKDLDPQGKRFDRVSRLIGRSE-NYEMDLTLDFNSEIYPMEKFSLVLASSLSLSDEYEYVMFGKVYRYEDRSV--YVSYGGLLMCLEGDYRHLQNLVGENIYLLIRK Mydma ------------------------------------MDLILDVNTQIYPVEKFRLVLVTTLRRADQFEYVMYGKVYRIDDNRLSAYVSYGGLLMRLQGDANNLHGMIDQHVYLLMKK Neucr2 DAQLFEDEFKVERISD--PKYDRVDRLYCTSV-DGQTSMQLDVNKELFPVEYLRIALATSLSLADSYEYVCHGKVYKFEDQTIKAYMSYGGLLMALDGPYKKLTPL--DYVYLLANR Orpsp11 DNKLFSDVFEIVEKDKGGKKFDRVSRIQGRSE-NYEMDLTLDVNTEIYPIDKYALMLASSLSLADDYDYVMYGKVFKYDD------------------------------------- Pench1 DPLLFEDTFTITSVNA--QKYDRVSRLTCNSN-DASLTFTLDVNTELYPCESLSLALASTLSLADDYDYVCHGKVYRFEEDTMAVFVSFGGLLLYLEGPYKKLAPL--DHVYLLLKK Phybl2 DNVLFQDLFDIKDINPNGKRFDRVSRLLARSE-NYEMDLTLDYNSEIYPLDKVSLVLASSLSLSDEYEYVMFGKVYRYDDQRVSVYASFGGLLMCLEGDYRHLQNIVGENIYLLLRK Picst3 -GILFEDMFVVESTDS--GRYNKVSRITGHSSTSQDIKISLDINSELFPVDSLTITLASSL-LADDYDYVMYGTVYKFEEDKMSVYVSFGGLLMRLEGGYRSLSNL--ENAYILIRQ Plicr1 SNIVFDDIFTISAIDKEGKKFERVSRLYAHSK-NYDMDLTLDYNIELFPLQSFALALASSLALEEDYDYVMYGKVYKFDGEIVTAYASFGGLLMALTGSFRHMTNILGDPVYILMRK Polpo SAILFEDTFEVKEIDPDGKKFDRVSRFICYGE-SYEMDLHIDIATHIYPMEKFKLVLASSLSLADKFDYVMFGKIFKYQKSKVSIFASFGGLLMLLQGDPRYLPGLLDARIYLLIKK Pucgr2 SSLLFDDLFTITNVDKDGKKFDRVSRLNASST-NHSMTLVLDFNVELYPLDSFALALSSSLTLADEYEYVMYGKLYKFDSDSVTAYISFGGLLMALTGDYRHLDRLVGQMVFLLMRR Punst1 SHIVFDDIFTVNAIDKEGKKFDRVSRLYAHSK-NYDMDLTLDYNTELFPLQSFALALSSSLSLEEDYDYVMYGKVYKFDSEISTAYASFGGLLMALTGSFRHMASILGEPIYILLRK Rhior3 ENILFQDIFDIKDLDPQGKRFDRVSRLIARSE-NYEMDLTLDFNSEIYPLEKFSFVLASSLSLSDEYEYVMFGKVYKFEDQQVSVYVSYGGLLMCLEGDYRHLQNLVGENIYLLIRK Rhoto1 SAIIFTDVFNVSDVDKDGKKFDRVSRIAAKSQ-NHDMRMTLDINTDLIDLSEFSLALASTLHLADDWDYVMYGKVYKYDEEEVTAYVSFGGLLMALTGVYRHMANLVGEYVYLLLRP Rozal11 SNILFDDYFEVRDINPEGKKFDKVSRLIGKTE-NYDMDLILDVNTEIYPMERFHLSLSHSLSLADSYDYVMFGKIYKYEPGKVAVYISYGGLLMRLEGELRHLSFVIAKYKRLLCKT Sacce1 -NTLFDDIFQVSEVDP--GRYNKVCRIEAASTTQDQCKLTLDINVELFPVDSLTVTIASSLNLADDYDYVMYGTAYKFEEDLIAVYYSFGGLLMRLEGNYRNLNNL--ENAYLLIRR Salro -MRLFEDVFTVKAKDPKGRKFERVSRIVCEAF-MTGFELILDLNTQLYPMEQFSLCLAR--SLADSFDYVMHGTIYRVEE-QVAVYASYGGMLMRLKGNRSALMKPLDSSLYLLIRK Schco3 SNIIFDDIFAVEDIDRAGKKFDRVSRLWSKSK-NYEMELELDYNIELFPLDHVAVALASSLSLEEDYDYVMFGKIYKYDEERSTVYASFGGLLMALTGNNRHLQNLLGESVYILLRK Schpo1 ESVLLDEIFTVTSVDK--QKYQRVSRITAVSG-QNDMNLTLDINSQIYPLATFSLQITSNLNLKEAADYIMYGKVYRVEEEKVSVYVSFGGLLMAIEGSHRKLYRL--DHVYLLLRR Sorma DAQLFEDDFKVERISD--PKYDRVDRLYCTST-DGQTSMQLDINKELFPVDYLRIALATSLSLADSYEYVCHGKVYKFEDQTIKAYMSYGGLLMALDGPYKKLTPL--DYVYLLATR Sphar -------------------VFDR---------------------------------------LADNYEYVMYGVVYKVDEDKRSIFASFGGLLMLLQGDRSNLAVLPREKC------ Spipu1 KNQLFQSTFEVKDMDPFGKKFDRVSRIRAEGQ-TLDVEVLLDVNTEIYPLDKFAFLLATTLSLADDYDYVMYGKVYKFDD--VSVYASFGGLLLCITGDQRQMQDFVGMNLYLLMKK Sporo1 SAILFTDVFIVTDVDKDGKKFDRVSRVAGKSN-NLDMKITLDINTDLLDLMTFSLALASSLNLADDWEYIMHGKVYKFDEDEVTAYVSFGGLLMALTGSYRHVSGVVGEYIYLLVRK Stehi1 SNVVFDDIFTVEDIDREGRKFDRVSRLYAHSK-NYDMDLTLDYNIELFPLQTLALALASSLALEEDYDYVMYGKVYRFDSEIVTAYASFGGLLMSLTGSFRHMTSILGDPVYILLRK Tapde11 --------------------------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------- Treme1 NNILFEDRFIVDEVDKGGKKFDRVSRIEATSQ-NSRMSLVLDIANELYPLETFTLALARSLLLADDYEYVMYGKV-----TGITAYISFGGLLMALRGPYRHLTGIVGQNVYLLIRK Trire2 DATLFEESFTVTDYDQ--SKYDRVARISCTSS-DSQTVMTLDINIELFPCDTLHVVLTTTLSLADLYDYVCYGKIYKFEENTINAYVSFGGLLMSLQGPVKKLTPL--DYVYLLVKR Umbra1 DNLLFQDIFDIKDIDPEGKRFDRVSRVRARSE-NYEMDLTLDYNTELYPLEKFSLVLASSLALSDEYEYVMYGKVYRFDEQKVAVYVSFGGLLMCLEGDFRHLQNIVGENIYLLMRK Ustma22 ---LFDTQFVVSQIDPDGKKFDRVSRIIATSP-SLDMTLSIDIATDIWPVQQLTFQLASTLKIADDFDYVMYGKIYRYDEDEVTVYGSFGGLMMALTGNFRHMSNIIGSNVYLLMR- Walse1 TSIVFDHLFTVDSIDKDGKKFDRVARVGAIST-TPNLNCIIDLPIEIFSLEKFTLALSTSLSLAADYEYVCFGKVYKFDEEIATAYISFGGLLLAITGHVRYLTDIVGEDIYLLIRR Zygro1 -NTLFDDVFLVADVDP--GKYNRVARIEATSTTQEHCKLALDVNTDLFPVEQVTATIASSLELADDYDYVMHGTAYRFEEDLIAVYYSFGGLLMRLEGNYRSLNNL--ENAFLLLRR [Cluster2185.fasta_al_trimmed; alignment length = 475] Allma1 VALASLLLFVQLNWT-GPLLTADGEPAYHRTLLAVALTLTANW-WHARAVRLQQHLLDNELEIALEKAQMASGLKFEVSGLLGRRTRFQENSITQLVVLAESVKTLALNDDTVLEKPKLEGTQNLSVLDQCILLSYCVK-NTNPADEITTEQMFPFVRRILPNNWTVHSMALLLRSRLESNKTRTVERAALQIQALVDQIDAPVSVRLQPIFAVSTPTRWALEAELADKMMSLGVVRTALDIFERLEMWEKVVVCDKAEALVLQLLPKFLCMLGDIYQEAWDASRFSRAMRALGGHHYRYAESVECWLKALRINPLAWFICGCAALHVENWDVAIEAFSRCT-ALDYENAEAWNNLATVYLRQRALQQGIKKYDSWKMWTNYMYLAVDLGHDEAMQAMTRVLEIRGKNVDAEVLRMIVDGILIVRLR-WKIAAYFRAYRCELF-EAYRDLGDWLYQSKLIVRALLGR-GDKVQEL Ashgo11 VAVALLQTFIQNNYT-GPLLSVQGQIAYELCYLVLALLFVAHW-WRFRALLVQISLIAEYLENVLQKVQKLTDFQFVLTGARAKRTKFQQKAHAGLIILARSPGALALNSDLLFEKPHFESQPRLSDYDNIQLLLRLIR-QTSPARDPVDEELASIIGRVVK-NWSVFARALWERSVLETTKAKTIERGILQMQSLVEELLTPASDRMKYIHQLPFLPRWALDRELAEKYMSMGILRSAVEIYERLELHCDAALCKQASLILQKRIARAYSILGDIWEKSWEVGKYVNAKNSLGKFYYDFNLSLKHLNDSLRLYPLTWYFYGCIGLECGKVDLAAEAFSRCV-ALDDTHALSWSNLSAAYTEQSCLKRAI-SQRNWRIWENYMTVSVKLHEEDVLLACRHLIELGRDKIDMPVLEKLSELLTCVSLICWRIVARVKAYRSELV-AAYESLGDWKYKARSTIKSLLNKGREKLVQL Aspfu1 IGLAALFSFMQSNIT-GPELSVDGEAAYKLTLFAVAMALLVARTARLRVNFLHQKMLSELVERALEQAAAVRKFEFALTGRLGKRTKFQEHDISQLVVLAKSPKNLDLNDDTLLESISFTKQPLLDPVDSAILLGLAIT-NTSPENGLTREETHPYAIRVLSSNWQVYTQALLVRSRVEGYRARTVERSVLQMQALVDQ-SASAAERLEYIWLLNSPTRWSLEAELAQRWVNLGGLRTALEIYERLQMWAEAALCEKAKHIVRRQLPRLLCILGDIYERAWEVSRYARAQRSLARHYLALEKAEEAYRKSLHINRLAWFALGCVQLELQKWEDAIDSFTRTV-QLEDTDAEAWSNLAAA----AALHRAAQKHTDARIWDNVLTVAASIPPRDVVTAQRRVIELLGSKVDIPVLSMLIDHVVILSLVLWLLVARVKAWRARLVRDGYAKFGDWRFKARSAVRGILGKGKNRLKEL Aurde31 AVAASLHAFLQANWT-GPELSYRGEPAYHLAFLRIAQIITVAW-WQLRVWTVHLYMLDEILEQGFVDAAKATGLQFELTGALGKRTKFQQNELSQLVLLAESPTTLELNDDTLLERTQFTSQPALDPLDQCVLLAMCVR-NTSPVHGLTNEQMAPYVSRVIPRNWSVHTMALLLRSRLEAGRTRTVERSTLQLQALIDQM-SSAAERLLYIHDIPLPSKWQLERELADRMLSLGVVKSALEIYTRLELWEEVVRCEAGVKIVRDLLAKLWCLLGDLYLRAWSISTSGRAARALGTLYFDYEKAVPFLEHGARINPLTWFLLGCAEMRKEHWEGARDAFAMCV-QVDEEDGESWNNLASVYLQLRALREGLKGYENWRMWTNFMLVSLDIGEHEVVRAMTRIIEERADKVDQEVLDKLVDGATVADLFIYKSYARLDAYRAATV-DVLRDLGKWRIQARGLVRTFAARSKARVEAL Batde5 IGIALLNSFVQGAWT-GPLLMSDYEEAYTLTLLLLARWITFRW-WSCRCAFIQQRIIENYLEYGFKAAQEASMLTWEMTGVLGKRTKFQTFETSQLVVLAESPVALDHNDDTLLEKMQITDQHNLSIVDQCILLALCVK-NTNPIHGLTTEQMFPYVRRVLSNNWMVHTMGLLLRSRLEIEKSRTAERSVLQLQALVDQF-SPVAERMQHIFSILIPPKWELERELGERFQGIGAIRSALEIFERLEMWENVVSCEKAKVIVCNLLPKLICLLGDIYMQAWEVSRYARAMRSLGAHYFNMEKCVECYQLALALNPLSWFVLGCAAMHLEKYDIAEQSFNRVT-VIDPENGEAWNNLASVYIKNNCLKESLKNFEASNIWENYLFVSVDIGESEAIRAMERILTIRANKVDLDILDIIVLAIVMAKLLLFLICARFKAYRAQVV-NAFVELGDWAYQAHQATKTAVARTKDQLVQK Botbo1 LGATCLRAFVQINWT-GPELAYGGEPAYHLAFLRIAQILSYPW-WNLRATLIHQHLLDDLLERGFVRAARATELKYELSGALGKRTKFQVSDLTQLVLLAESPETLALNDDTLLEQTEFTSQPALHPLDQCILLSLCVR-NTSPKHGLTSEQMSPYVARVIPKNWSVHTMALLLRSRLEASRTRTVERSTLQLQALIDQM-STVTERLLYFDAIAIPSKWELEHELGMRFLSIGVVRSAMEIFERLEMWEEVVQCDKGIAIVKDLLAKLWCLLGDLYKRAWEVSTSGRATRSLGGYYFAYAESIVYLRQAVEIHPLTWFLLGCACVREERWDEARDAFTRCV-SLDEEDGESWNNLASVYLHMRALKQGLKSYENWRMWSNYMIVTMDVGESEACRALGRVIEMRSEKVDIEVLERLVGAVTVADLFIFRAHAQLNAYRCELV-EVMRNLGSWQFQARSIVRTFMGRTKEKLSVL Botci1 TGLAAFNAFLQTNVT-GPSLDVDG-----------------------------------LLEKAVKKASEVSGFEYALSGALGKRTKFQQTDISQLVVFAKSPQALELNDDTLLESIEFAKQPQLHPLDQIALLTEAKD-TLSPLDKLNSEEILPYAVRVLPTNWQIYTQALLVRSRIEAHRSRTQERSVLQLQVIVDQISAPVTERLRYVNQLNTPTRWEIETELAFAWSNAGSLVSALEIFKRLKMWAEVALCDKARQIVRRQLPRLWCILGDLWQRAWEISRYARAQRTLGDYYTDLTAAREAYLASVVVNRQTWSRLGDIDLKTGNWDGAVIAFQQSI-MIDDTDAKTYSNLGSALLSKMAYKRGAAAHNNWKIWDNVITIATRMSPPEILMGLRNILRIRAPNIDMDILSSLVIEVVVIEMMLYEMVEKLKAWRMRLV-GAYENFGKWKGKARSAVRGVMGKGKETLEGL Caeel CGLNIPNAVSKSLWA---DLSDIPPIGYRVI--------YLVW----------QQLLIDQLEMAIKSASEECQLNMDLSGMMGKRTRFQQRDIAQLVLIHKDPQSLDMNDDTLLEQVAITE----RTLNACQLSCLLRHESATHRHDVVHERCSPVLDTVIRRYWSIQAAALLARAELERGRVRQVDRSCTQSELVVKLQIKDRLLRTSYILASGLTPFWQSSVLLAGILNSLGCTSEALLILEKLEMWDGVIDCDKAETLIRRLISMLHVYLGDIFTKAIELSRNARAHRSLGHLLLKFEEAYKHLRRSLELQPITWFNAGYCAWKLENFKESTQCYHRCV-SLQPDHFEAWNNLSAAYIRHKLLQEALKNYEHPNVWENYMLLSVDVGESQAIQAYHRLLDMNKRGADDEVLELIAQTLLMIKLLTLRVYALLKSLAARLAEDRLE---EASAKVRLSLRGILTRLDQEIVEV Canalb1 LGVACLQSFVQANFT-GPLLSIEGQQAYDLMFLVMSELISLCW-WKVRGLQVHLSVVSELLEVSLIQAKKLSDFQLLLSGAKAKRTKFQNFFTSNLIVLAKSPESCQLDSDLLLEKPQYESQPALNNLDNLQLLLRLLK-QTSPASDPVEEELSALVGRVLKVNWSIFSRALWERSLLETNKSRTIERGILQMTSLIEEMSATTASRLRFIHLLPLLPQWAMDAKLAEKYMSLGVLRSAIEIYERLHMSCEAALCREAENIILQRLARAISILGDIWEKAWEVGHYAKAKASLSHYYYDIDLAIKHMFDCLTVNPLNWYFYGCCGLESGQFELASEAFTRCV-SLDDSNSYAWSNLASALLKLNALKKAIRSRKSWRIYENYVNVAAKLHENDVLQGCRELIEIR-KNIDIPVLEKLVEILVCIDLVCWRIVARVKAYRVDLV-SAFESLGDWKYKARTTVRSLMSKGKERLQNM Cangl LAIASLQLFAQNNYT-GPLLSSAGQMAYEYMALTLALLLIAHW-WRARALLAQLSVLPEYLESVLTKVKKLTDFNFVLTGARAKRTKYQQKAVSGLLILAKSPDVLQLNSEILLEKPTYEDQPTLSDYDNIQLLLRLLR-QTSPAFDPVEEELGALVGRIIK-NWTIFSRALWERSVIETTKAKTIERGILQMQSLVEELYESSMPRLKYIHQIPFIPRWELDAKLAEKYMSLGVLKSAVEIYERLGMSCEAALCKKAEQMLLNRIARAYSILGDIWEKSWSIGKYVNAKNSLARYYFNYGLALKHLNDSLRQYSLTWYFYGCIALECNKMEIAAEAFTRCT-ALDPTHAMSWSNLSAAYVQQSCLKQAI-SQKNWRIWENFLLVSVKLDEEDVLAACKQLIEIKKDKIDLPVVEKLVELLVCMDFICWKLAARVKAYRADLV-AAYESLGDWKYKCRSTIKALMSRGKEKLLEL Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 VTVPALLLFTQLNLT-GPLLTADGEVAYHMALLALAFS-KLAW-WHARSQRIRQLLLDNELEMTLGKAAQASGFEFEVSGLLGKRTKFQQNSLTQLVVLAESNKDLQLNDETLLDKVALEGRRISS-----------IK-QTNPHDAITTEQLQPYIRRLLPNNFSVHSLALLWRSRLESAKSRTVERAMLQLQTLVDQIPTPASTRLHWLFALQSPTHWSLETELAEAMLNLGLLRSALEIYERLELWEKVAVCDQAEKVVLAQLPKYLCLLGDIYWESWEVSRFARAMRSLGQVYFEYVQSVECYQRALAINPLAWFICGCAALQCSNWDAAQVAFARCT-SMDHQNAEAWNNLATVLIKQQALAQGVKKYDSWKMWTNYMYLAMDLGADEAMRAMQRVVEVRSAHVDVEVLNLLVRSVMVARLAVWLAAANFRAFRAVLI-EAYQDLGDWAYQSKLVVRGLMGRIKEVLSGM Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 IAVAALHAFLQSNVT-GPSLNADGVAAYRLTLLCLADTIVSVW-ARLRTNFIHQRLLSELLERALDQAASERKFEFALTGLMGKRTKFQQKDTSQLIVLARSPKKLDLNDDTLLESISFTNQPLLDPLDSVIMLSLAIK-NTNPADGLTREQTEPYATRVLSSNWQVYTQALLVRSRIEGYKPRTMERGLLQLQALVDQ-SASVEERLRYIFPLCSPSRWELESELAARWVALGGLRSALEIYERLELWAEAALCDRARKIIRRQLPRYYCILGDIYEKAWQVSRYARAQRSLGQRYIDYEKAAEAYSLSLKINALAWFALGCARLELHEFKNAVEAFSRCV-QLDDQDAEAWSNLAASLLHLKAFKRAATKHDDYRIWNNVLAVATSTSPQDAITAQRRICELRGQTVDAEILNMLVKHVVANDLILWIILATLKAWRADLV-DAYETLGDWKFKSRSAVRSVMGKGKEKLVER Coere1 VGAACLNAFIQTNWT-GPIMEVDGEEAYALAYLYLARLLSARW-WAARTLSIQQSLLDYLLELGLSLAQAASGLQWKMTGAKGRRTRFQTFDVTQLVLLAKSPESLELNDDTLLENIKFTDQEDLQTIDKCILLALCVQ-NENPAHGLTSEQMMPFVVRVLTGNWSVYTMGLLLRSRLESAKSRTVERATLQMQTLVDQI-AGAAERLRYLSVLSLPSQWEMERELANMFMELGVVRSSLDIYERLQMWDEVISCEVAERIVRREIPKLWCVLGDLWRHAWEVSRYARAMRSLGAYHFEYAASAECYEKAVNLNPLSWYILGCAAMHIGNWQLAIKSFLHVV-RIDENNGESWNNLATVYLRLHALREAIKKHESWQVWSNFLHVSLGLGLSLSIQAMGRMVDLRAAKIDVDSLRSMIGMMSMEALLLWRVMADYKAYRCTLV-EVYENLGDWRRQSKMLLRGLIGKGKTRLTEA Conco1 LSIALLNYFVQVGWT-GPDFSVEGEDAYHLALLWYSETLSSNW-WLSRALFFKQRLLDNWIELGYDKSKEWSGLQYLLTGALGKRTKYQQRDISQLVLWAKSPETLALNDDTIMESIKFAEPSSLAKVDQCILLAYCIK-NTNPDHGITNEQMVPYVTRVLPNNWMIHTMGLVLRSRLESTKSRTVERSVFQLQALVDQW-SQVTERLEHIHSLLLPSKWEMEKELAERFMSLGIIRSALEIYQKLELWEQVINCDHAKAVIEEQLPKLLCLKGDAYHRAWDVSRYARAMRSLGSYYFEFNSSVGCYVKALTINPLSWYLCGCAAMQCEDYEVAAKAFRQVI-SIDDENAEAWNNLASIYLKLLAFKQALKKFENWKIWTNYMYTSLDMGYGEAIRAFEKIVDLRWQDVDQEILGIFIDAVLLESLLIWKLYARLKAYRAELV-DSYQSLGDWNYQSRMLLRNLIAKTKNLLVSA Conpu1 LAVACARAFVQPNWT-GPELASGGEPAYHLAFLRLAQILSAAW-WRLRVTIIHQQLLDELLEQGFVRAARATGLRYELTGALGKRTKFQVADLSQLVLLAESPETLALNDDTLLEKTEFTSQPALHPLDQCIFLAMCVR-NQSPSHGLTSEQMSPYVQRVLPRNWSVHTMALLLRARLESTRTRTVERATLQLQALVEQM-APLGERLGYVHDISLPSRWEMERELAGRFLSLGVVKSALEIFERLEMWEEVVKCDKGIAIVRDLLAQLWCLLGELYEHAWALSTSGRAMRSLGGYYFEYAKAVPCLERAVKINPLSWFTLGCAYIRLEKWEGGRDAFSRCV-TIDDEDAESWNNLASMYLRLQALKRGLKKYDSWRMWTNYMVVAMDVGEAEACRAQGRIVELRAAKVDADVLERLVDAVTVADLLVFRAHARLDAYRGDVV-DVLRNFGKWWVQARSIVRTFMGRSKVRLTAL Copci LAVACLHAYVQANWT-GPELAFGGEPAYHLAFLRLAQLISASW-WRLRTTIVHQRTLDETLETGFVTSARITGMEYELTGALGKRTKFQVNDLSQLVLLAESPETLALNDDTLLEQTEFTSQPALHPLDQCILLSLCVR-NTSPAHGLTNEQMAPYVARVIPRNWSVHTMALLLRSRLESTRTRTVERSTFQLQALIDQM-STLPERLLYFHSIPLPSKWEMERELALRYMSLGVVKSALEIFERLEMWEDAIKCEKGIAILRDLLAKLWCILGDLYQHAWEVSSSGRAMRSLGGYWFEYTEAIECLKRAVAINPLPWFLLGCAAMRLEDWALGRDAFIRCV-TIDEEDGESWSNLASMYLRLRALKQGLRSYNNWRVWYNYMIVAVDVGEQEAARALGRVVEMVADKVDDDVLDRLVDAVTVKNLFIFRAYARLDAYRCDIV-DVLRNFGKWRLQARSIVRTFTARTKGRLKEL Croqu1 VIASLLSIFVQVNFT-GPRLSLAGEPAYHLTFLFLAIELTLVW-WELRAGILQRKLIEETLERGFLRAAEEAGLEYELTGILGKRTKFQEHDLSQLVVLARGPITLALNDDTLLEKTQFTSQPKLHPLDQSILLALSIK-NTSPSHGLTKAQMAPFIERVLVSNWSVHSMALLIRSRLEAHRSRTVERGLLQLQALVDQLQSSARERVRWTWGLGLPSKWELERELGRKLVGLGVIRSAMEIFERLEMWEDVVQCPIGVQLVKDLIGKMWCLLGELWQTAWDVSTSSRAMRSLGAYYFDYFKTKECLSVALKINPLTWFIYGCAAMRLEDWAEAEIGFRRCI-ILDDEDAEAWNNLATVHLKQQALQRAVKSYDSWRMWTNYMIVGISIAETEAIRALGRVVEIRGQELDHSVLDKLVEVAILSEVMVWESMSELNAYRVRTI-NKLEKFGNWKWQSKSILRSFLSKSKTELDER CryneH991 TAIALLHSFVQINWT-GPFLTLHGEPAYHLSFFLLARRLTLPL-WLLRLHLVHLSLLDEHLELGFLTAAKASGLEFELTGALGKKTKYQVAAHSQLVLLAESPESLLLNDDTLLEETEFTKQPALHPLDQSLLISFCQS-NNTPSSGLTAQQMMPFLSRVIPRNWSVHTTALLLRSRLEATRSRTVERSTLQLQALIDQM-SEPKERLRYFHQLPLPSKWEMERELAKRFMSVGVIRSALEIFTRLEMWEDAIMCEEAIDIVKDLLGKLWCLLGDLYEKGWEVSTSSRAMRSLGSLYMEYEKAIACFNSALEINPLVWFTLGVAFLRLEKWKDARDAFRKQV-GVDEDDAEGWNNLAAVYLRLRALRQGLRAYANWRMWQNYMIVAIDVGESEAARAMTRIVEELANRIDADVLDKLVD---VERLFVWRTHARLRAWRFDLV-AVLSVLGDWKFQARGLVRTFMGRTKQRLQDL Crypa2 VGVEAFNAFLQANVT-GPSLEVDGVSPYPFILFCLAKHSSLAW-MRLRLDVWHYKLFIELVEKALSAAADLNGFVYALSGALGKRTRFQEKSTSQLVVLAKSPEALPLNDDTLLEEIEYTNQPQLSALDQIILLTQAKD-SFSPADKLTAEEVLPFAVRVISTNWQIYTQALLVRSRIEQHRSRTVERGVLQMQAVVDQVSAPASVRLEYIHALSSPPRWHLESELAYAWTGVGSLVSALEIFKRLKLWAEVALCDKARAIIRWRLPRLFCILGDIYERAWEISRYARAQKSLGEHYLDWKKAREAYQLAVSVNRLMWSRLGDINLRLGDFAAAAEAFTRSIGSSNDTDARTWSNLGSALYSVNAYKRGASAHDNWRIWDNVITLATRMRPFEIIQALRSIIRIRN--LDDDILRVLLTEGVVNEMMLWELLSRLKAWRAELV-AVLENFGKWRAKARSAIRSVMGKGKNTLKGL Debha1 IAIALLQTFIQLNFT-GPLINIEGEQAYELMFFIISCLLSLQW-WRARALQVHLSLISEFLECALGKARQLSELNFVISGAKAKRTKFQTFHTSALIILAKSPETFGLESDLLLEKPQFESQPALNDLDSVQLLLRLLR-QTTPSNNPVEEELLALASRILSVNWSIFSRALWERSILETTKARTIERGILQMTSLVEEISSAAASRLRFIHQLPLMPQWAMDMRLAEKYMSLGVLRSAVEIYERLQLSCETALCKEAERIILERIARAVSILGDIWIKAWEIGKYSKAKASLSRYFYDLEQAIKHMNDCLTANPLHWFFYGCCGLESHQYEVAAEAFTRCV-ALDDTNSHAWSNLASALLRTNALKKAIRSNKSWRIYENYLIVAAKLNENDVLIAARELINIRGNSIDIPIIEKLVEILVCIDLVCWRIVARVKAYRADLV-AAYESLGDWKYKAKTTVRSLMSKGKYRLQDM Dekbr2 LAVLFLQIFVQLNFT-GPLLSIEGQQPYNLVFLALACNI---------------NIISS-LELALSRAGDISGIELVLTGCKAKRTKYQHKSIAALTVLAKSPQDVKLNDDTFLEKPVFDEQPALAGLDYAQLLSRMIK-KNTPKGNAVDEELIALVQRVLSVNWLLFSRALWYRSLLEASKRATVERGVLQLYSLVEELVLANSIRLRYVYVISAMPKWEMDSQLAHKLTELGLFKSALEIYERLRQWPDAAVCVNARSVIEKAVARAWCILGDVWEKSWELGHYANAKSSLAKYYYDVKKAIDNMYDCLCSNPINWYFYGCMGLEVSNYELASEAFHRAL-NIDDSSPYAWSNLASALIKLQALSKAINTKKSWRIWENFLTIAIKLGKSDVLRASIILLNSDKTSLDIPVMEKLIGVLTCIDFVCWKDIAKVKAYRADLI-KAYQDLGNWKFKAKSSIRSLISKGKERLQKM Dicdi SGITFLNLYVQINWT-GPLLEVDGETVYKKVFLYLSKICSSCW-WSCRSVMYHQRSLKNIIEQSMERACEVSELDCALTGALGKRTRFQTFDTAQLVMEVKNKREVTNDDPTLLVRPSLIENILLRNVDQMLILLQCVK-NQNSNNGLTTEEMLPYIQKTLSNNWIIHSMGLLIKSRLEIVSSKTAERAVLQIQALVDQY-SSATERINAIYSTDYPARWDLEKEVAERFIGIGAAASAFEIFERLEMWDEAIKCSRSEELVLQRLPELYCVLGDLYIKGWELSRYSRAQRSLARFYLQYQLCIDAFQIALAINPLSWFSLGCAAMKIEKWDTALNAFSRVV-SLEPEEGEGWANLASIYMYQSALMEGLKKRENWKMWENFLFCCIAIKDQNAVIAINHIFDLNDKKVNLKLLSIIADHVVVSELFLWRLYSSYKACRSTLC-DLYF-QYSNIYSAKLKVKSILKKCEKNFEQL Dmel DFLLLIFAFVQNSFT-GPKLKASGEELNPNVLLLIAREIVLIW-WRLRLICLHQHVLDDLLELALDELCKHLQVELKVEGLLGVRTKFQQKALPQLCLKVEHPKLLLLEDDTRLERIRFVE--TLPSVLQALVLAKVLK-RSTPKDRLADEQLEPYTQTLLHGPFQVRQSALLLNCLQESNQRRTVERSWKQCEECVKLLELSLRSRLSYGFAAHLSPKWQVQLQLVDLLRSLGMTKTALDICLRIHAWQQVIECHKAAEIIRQELALLYCLLGDAYEQAWLYSTSGKAQAYWGNHFYDYAQAMDHFEISLEINNLILLRCGYCAIQLERWEPAVKYYLAYT-HLEPNGFESWNNLAKALIKLRVLGEALKNYSNWKVWENYMLVSVDTSHDDAMRAYQRMAELKQHYLDQEVLTRIVYGVSLIKLLVWELAALVKSYRAEVCDLSVAAITSQLNSARLAGTSCLNALKEQLEKR Enthi IGVTLLNGFVRMNFV-GPYLSIDGEQANKHIWLHTSAKI-----FIGREAMIHQRVLENKFKMNLNKISQEEKIFVELSGAMGKRTKYQEKETAQLYVRVERKETELEEDNDMLSQTDYSGYTPLSTYDEAYVLMECRY-RKNCKSELILEEVIPYCNRVLRIDFSTFIMSVLLKSRYEATVTHFLWRSVKQADDLVKMMEISSEERLESIYMTMIPNIFSLRKETGMRMLLMGESGAAINYFSGLDMKIEIVAAEKAEEVARELLPELKVLMYEILIESWEESTYVHAERILGQYYFEWKEAKKHFDIALEINPILWFALGICCMQISDIAGAKKAFLKGV-NLDSDDGQSWANLAYIHSIQVALKEAVRIRTSEDLWKNLIIISIDIKDRQAISGIVSLYDVNKSAINPKILSMMCDVILMIPLLVYQVA---------LL-------------------------------- Falba LGAALLQAFVQANWL-GPWVSQDEADAYPLLLLIAAVLLTALL-WSARVTFAHQRMLDDYLEHALVAAQAATGLEWELTGALGRKTKFQLDARTMLVVFARYPKALDLNDDQLLDRMRLDDSEAIFPLDQAILLGFSFK-LKDPSSDLTSTELTAFVEYLIPKNWLVHSSTLLLRSRLEASKTRRLERATLQIQALVDQFEPGVASRGSLFYQLDYPNLWRMQSDLATLFTKLGLLKSALDLFEKLENWEGLITCSRAEAVVREQLPKMYCILGDIYEQALALAHYARAHRALGLIHFEVERALPHLEHASRLNPLNWWTLSGAYAKLENWPKAAGALTRVV-SLAPDDAEAWSNLSIYYTKMRSLKEATRNRDSWRMWENLVLVSLVVNESDVILGMSRLLEIRKDNIDEQNFGRLIHAYMLESLVVLAICAQFRAYRAAAV-EALLARATDLYQARTIIRGFLSRAKQAMEEL Fomme1 IGIACLHSFIQVNWT-GPELAYGGEPAYHLAFFRLAQILSGAW-WRLRAARIHQHILDEALECGFVRAARYTGLEYELTGALGKRTKFQQTEVSQLVLLAESPETLALNDDTLLEQTVFTSQPPLHPLDQCILLSLCVK-NTSPAHGLTQEQMKPYVARVIPRNWSVHTMALLLRSRLEAERTRTVERSVLQLQALVDQM-SPLSERLLYIHSLPMPSKWELEGELAMRFLSLGVVRSALEIFERLEMWEEAVKCATGIEIVRDLLAKLWCLLGDLYSRAWEVSKSGRAMRSLGGYYFEFAKAIECLRKGAAINPLPWFILGCACVREERWEEARDAFSRCV-SIDDEDGESWNNLASVYLRMRALKTGLKSYDNWRMWTNYMIVAMDVGEAEAARAQARVVEERAAKVDEDVLDRLVDAVIVLDLFMYRAYARLDSYRLEIV-DVLRNFGKWKMQARSIIRTFMARTRSKLVEL Fusgr1 VGIAALNAFLQVNVT-GPYLDVDGVSPYAYILFSLARFISLAW-TRLRVNVWHYKLLTQLVEAALKEASQTSGLEYALSGALGKRTKFQENSISQLVVLAKSPDALQLNDDTLHEEIQFSKQPQLSPLDQIILLTEAKD-AFSPIDTLTSAEVLPYAVRVISTNWQIYTHALLVRSRIEVHRSRTVERGVLQLQAVADQVSAPAHVRLEYIHAICSPPRWHLESELAYAWAGIGSLASALEIFKRLRLWAEVALCEKAKGIIRWRLPRLFCILGDIYERAWEISRFARAQKSLGEYYLEWEKAREAYKKATAVNRLMWSRLGDISLRLAQFRDAAEAFNRSIGSASDTDARTWSNLGSALWSLAAYKRGASSHDNWRIWDNVLTLASRVQPADMVVALTHIIRIRK--LDVDVLGALLQDAVVMRLFLWALISRLRAWRAELV-SVYENWGK-----------------HDFQPL Galma1 IAVACLHTFVQANWT-GPELASGGEPAYHLAFLRLAQLLSIPW-WRLRVQALQQQILDEYLEIGFVQAARSTGLQYELTGALGRRTKFQETELSQLVLLAESPETLALNDDTLLEQTEFTSQPPLHPLDQCILLSLCVR-NTSPSHGLTAEQMSPYVSRVIPRNWSIHTMALLLRSRLESSRTRTVERATLQLQALIDQM-SSVSERLLYFHSTPLPSRWEMEKELAQRFLSLGVVKSALEIFERLEMWEDVVKCEKGVSIVRDLLAKLWCLLGDLYNRAWELSTSGRAMRSLGGYYFKYHEAISCLNRAVKINPLSWFILGCACMRVEEWTDAKDAFARCV-SIDEEDGESWNNLASMYLRIRALKQGLRSYENWRMWYNYMIVAMDVGEQEACRALGRIVEQTGEKVDEDVLERLVDAVTLLGLFIFRAYARLDAYRCEIV-DILRNFGKWRLQARSIARTFIGRTRGRLTVL Ganpr1 LANASLCLFVQNAWT-GPWLSADGEDVYHLTLLWIARLITLSW-WNLRSLLFQQRILENYLECGFEDAQRSSGFFWQLTGALGRRTKFQQTDVSQLVISAKSPENLKLNDDTLLDTIELTNNRPLNVADQVILLSFCVK-NTNPKDGLTNEEMGPFVRRVLPANWSVYTMALLLRSRLESEKSRTVERAALQLQALVDQF-GPPAERMMWIWALDLPPKWQLERELADRFMSIGVTASALEIYTRLEMWEQCVDCAKAESLLRQLIPKYWCLLGDLYEKSWALSRYSRAMRSLGSLHFNYSKSVECYEAALAINPLTWFMLGCAAMQISDWESAVRAFAKVT-NMNWENGEAWNNLASVYLQLRALQQALKNFDSWKVWQNYLYVSVDIGDEEAVRSTSRLLELRAHSVDLEVLDIILKAVNVSELLLWTLASAFKAYRAELV-DAYERIGDWKYQAKMVLRTVIGRTAEQLRNR Gloin1 IAIACLNAFVQISWT-GPILSVDGEETYHLTYLLISRIITSLW-WAQRVLFIQQRILDNYIELGFLKAQKSSGFQWKITGALGKRTKFQTFDVSQLLIVANSPDNLILNDDTLLEKIEFSKQKNLKVIDQCLLLAFCIK-NTNPSHGITIEQMVPYVSRVLPNNWMVYTMALLLRSRLEKAKVRTVERSVLQLQALVDQF-SSAQERISYFYQILLPPKWEMEKELAVQYLSLGVVRSSLEIFERLEMWEDVINCEKAKQIIHEQLPKLYCLLGDVWEHAWEISRFARAMRSLGGYWYEYRKSVDCYANALKINPLSWFIQGCAAMHLEEWEIAIQAFSRVI-AIDPENPEAWNNLASVFLRQNAFQQGLKKHDSWKIWTNYMYIAIDIGEAETMRAMQRVVDLRWEKVDVEVLELLINAVTLENLLIWKLCAQFKAYRSDVV-EAYQNFGDWKYQAKSLLKSLIGKTKDKLKET Hisca1 IGIAALSAFLQSNVT-GPSLTVDGEAAYKLTLFCLAKAILAAWSSRMRVNFLHQKMLSELIERALERAAGETGFQYALTGKLGKRTKFQDRDISQLVVLAKSPKTLDLNDDTLLEAISFKKQPKLNALDSIILLSIAIT-NTSPEHGLTREETLPYATRVLSSNWQVYSQALLVRSKIEGYRSRTVERGLLQLQALVDQVSAPASDRLQYIWLLNFSTRWDLEAELASRWVSLGGLRTALDIYERLQMWAEVALCEMARILVRKQLPRLFCILGDIYERAWTVSRYARAQRSLARHYLSLEKAEEAYRKSLAINRFAWFALGCVQLELEKYEDAVESFTRSI-QLDETDAEAWSNLAAALINLAALKRAAKKHTNHRIWENLLTVSASIPPRDVVYAQKRLIELRGPKIDINILTALVNSLTILNLLMWLLVAKVKAWRARVVREGYATFGDWRFKSRSAVRSVQGKGKRRLKEL Klula1 VAIAFLQCFIQNNFT-GQLLNVSGQTAYELCYLILALILLAYW-WRSRAILVQLSLVAEYLENCLTKVKKLTDFEFVLTGAKAKRTKFQQIAHSGLIILAKSPDTFELDSDLLLEKPHFEAQPALSQYDNIQLLLRLIR-QTSPANNPTEEELSALIARVLK-NWTVFSRALWERSIVETKRAKTVERGLLQMQSLVEELVESTKQRLKYIHQLPLIPRWSLDATLAEKYMSLGILRSAVEIYERLHMACEAALCKQAEQILVNCIARAYSILGDIWEKSWEIGKYVNAKNSLGRYYYDYTAALKHLNDSLRISPLTWYFYGCIGLECGKMNLAAEAFSRCV-ALDETHSLSWSNLSAAYVQLSCLKRAI-ARKNWRIWDNYMIVSMKLGEEDVLLAFRNLVDLRKDKIELPILEKLIEILVCLEFVLWKLVAKVKAFRADLV-AAYESLGNWRYKARSSIKTLMSRGKDRLMDL Lacbi2 LAVACLYAFVQANWT-GPELAYGGEPAYHLAFLRISQLLSAPW-WRLRATLVHQQVLDEYLEQGFVKAARATGLEYELTGALGKRTKFQETELSQLVLLAESPETMALNDDTLLEQTEFTSQPPLHPLDQCILLSLCVK-NTSPSHGLTSEQMSPYVARVIPRNWSSHTMALLLRSRLESSRTRTVERSTFQLQALIDQI-STLSERLRYFHSIPLPSKWEMERELALRFLSLGVVKSALEIFERLEMWEEVVKCEKGIAILRDLLSKLWCLLGDLYERAWEISTSGRAMRSLGGYYFKYPRAITCLKRAVAINPLSWFILGCASMREEDWEGARNAFSRCV-ALDEEDGESWNNLASMYLRLRALKEGLRSYDNWRMWYNYMIIAMDVGEQEACRALGRVVEETGDKVDEDVLERLVEAVVVSILFIFRAYGRLDGYRIDIV-DILRNFGKWRLQRRSIVRAFMARTRGRLVEL Lenti61 CAVSCLHAFIQANWT-GPELAYGGEPAYHLAFLQLARLLSAPW-WQLRTWRIHEQLLDELLEQGFVRAARATQLEYELTGALGKRTKFQEHDVTQLILLAESPETLALNDDTLLEQTAFTSQPALHPLDQSILLALCVK-NTSPAHGLTAEQMAPYVARVIPRNWSVHTMALLLRSRLESSRTRTVERSVLQLQALVDQM-SAVAERLLYIHEILLPSKWEMERELALRYLTLGVVKSALEIFERLEMWEEAVKCDKGRALVRDLLAKLWCLLGDLYTQAWEVSSSGRAMRSLGGYYFKYPETISCLRRAVAINPLSWFVLGCACIRVEDWEGAREAFVRCV-SIDDEDGESWNNLASVYMRMRALKQGLKSYDNWRMWNNYMIVALDVGESEACRALARVVEERAAKVDEDVLDKLVDAVTVDDLFIFRARARLDAYRAEIV-DVLRNFGNWKLQARSVVRTFMGRTKARLVAL Malgl1 VAIAALHAFVQLNWT-GPYLTLHGEPAYHLCFLVFSLLLSLPW-WQLRARSVHIRVLDETLECALVEAAKMNGLEYELSGALGKRTKWQKEDKTQLVLLAESPATYSLNDDTLLEQTQFTKQPPLAVTDQCILLALCIH-NTQASHGLTSEQMSAFVERVVPQNWSVHTMSLLLRARLESTRTRTVERSTLQLQALIDQM-SSIRERLRFFHALDLPAKWSMQCELADRFVSIGMLRSALETYERIEMWEHVVQCQEGRDIVRDLLAKLWCLLGDLYLHAWDVSTSARAARSLGGYHFAHEQAAVWLRRTVRINALAWFMLGCSYMRMERWLEAAAAFRKCT-ALEEEDGESWNNLASCYMRMKALGISLKQFDAWRVWSNYMIVSVDVGMSEAARALARIVEIRTREVDMAVLNRLVDAVVVLRLFIWLSYARLQSFQCELC-DALANLGDWQFRARTLVRSFMSRTRSELADL Mellp23 VVATLLSIFVQVNFT-GPELSLAGEPAYHLTFLCLAIKLTLAW-WELRAGILHRKLIES------------------LTGILGKRTKFQEQDLSQLVLLAKGPITLALNDDTLLEKTQFTSQPELHPLDQSILLALSIK-NTSPSHGLTKAQIAPFIERVLPANWSVHSMALLVRSRLEAHRSRTVERGLLQLQALVDQLRCTAKERVRWCWTLELPSKWDLERQLGRKLIGLGVIRSAMEIFERLEMWEDVVQCPIGIQLVKDLIGKLWCLLGELWKTAWEISTSSRAMRSLGAYHFSYTESYECLSTALKINPLTWFICGCAAMRLENWEDAEMAFRRCI-SLDDEDAEAWNNLATVYLKQHALQQAVKSYDSWRMWTNYMIVGMSIGESESIRALGRVIEIRGEDLDLDVLEKLIQVSILKDVMVWELMSNLTAYRVRTL-DRLETIGNWKWQVKSILRGFLSRSKVLLDSR Mnele FAVSALNVFIQNNFT-GPGYSSLNNAMYPLVLFGMCREYTTQL-FKLRCIFVEQMLMEDFVEIGMGLAQKLIGFSFKLTGSLGKRTKFQEKALPQLTIIEENPQIIDLNDDTLLEKISFEDQNSVTNLTAPFLLHMALK-DFALEEML-REEVIAFLEGIITFSYCIATHAFFIRSRLEQKSIRRLSRCMEQLEEVVLGFCKKVCARTGSLLQSGLPPMWKQEKLLAVMYTSIGSHKSALEIYSRLQMREEQINSETAEKLTRTLLPKLYCILGDTYEKAWELSSSARAMKSLGYHYFEYRRALSCMQKSLDCNFLLWFTAGCTALAIPEYGIAIKCFQSSL-QIDDENGQGWSNLGACFERTNCYKEATKSFNDWRVWENFLCAAAQIKDASMIFAYRQIISFGQKYCDRKILNCLVSAVRVLDLFLWKSYAAMKAYHSSIL-QILITKGDDGIETKDLIAEYLNSAKQLFV-- Monbr -------------------LCA------IWL---------------------------QHVQAAL----TTEEM------------------FPYV------------------------------------------------HYVL-------------PQDWSLHTMALLTQARLEKAKVRTLQRACEQLDAVSGLYAAPAVARLRYLSCVNLPPHWKLLRELGRVYNSLGIYRDALEIFQRLELWEGVISCEQAEALVRRRLPDLYCVLGDLYDQAWELSRSSRAMRSKGIFLLKYEKAIEAFEACLKLNHMVWFSLGACGLRLERWPLVCKAFRRKV-EIDDDDFESWNNLANGYVKTYAFHEASRAYDNWKVWENLSAVAVDVGAQDVLHAIERIMDIKKSYDDFEVLSALVHALVVRAACVWISAARFNAYQLDML--------KQLSSSRLLVRGAIKSVEADIRAL Morel2 VGIASLYAFVQAGWT-GPNLSVGGEELYHLSFLHFAKILSAPW-WALRTLFLQQRTLEGWIEKGFQKAQSTSGFRFKVTGALGKRTKFQQYDTSQLVVVAESPKNLEHNDDTVLEKIQFSEIEDLHPIDHALLLAFCIK-NTNPAHGLTVEQMFPFVTRVLPNNWTVYTMALLLRSRLEADKSRTVERGALQLQALVDQT-STTRERMHHFFSVLLPSKWELEKELAEQYMALGVVRSAMDIFERLELWEDVIACDKAKALCYTLLPKLLCILGDLYKEAWEASRFARAQRSLGAYYFQFQEAMTAYQLALKINPLSWYVLGCIGMQVEDFDVAIEAFTRVV-SIDQSNGEAWNNIAAVHMRRHALRQALKKRESWKIWSNYMYCSMDVGDTEAIRAMGMLVELRWKAVDIVILDRIVQGLTIEELLIWRICVKFKAYRSEMV-DWYRNLGDWAYRSKQMIKSLMARTREKLQDT Mucci2 TGIACLNTFVQINWT-GPSLSVDSEEVYHLTFLAIARTLTGSF-WAMRSVFIQQQLLDEELEVAMESAQKESGFTWSLTGSLGRRTKFQSFDVSQLVVLAESPETLDLNDDTILERIQFTEHGNLNVIDQCLLLAFCVK-NTNPDHGITAEQMVPYVTRVLANNWMVHTMGLLLRSRLEANKGRTVERSALQLQALVDQI-SGVEERLAYFYDLLLPSKWEMERELARRFVSLGVVRSAVEIFERLEMWEDVISCQKAKDVLKRLMPKYWCILGDLWRKSWEMSRYARAMRSLGSYEYNYESAIDCYQKALSINPLSWYILGCAAMFVENWEVGSRAFQRVV-ALDDDQPEAWNNLASIYIKMLALKHATKKFDSWKMWQNLLFVSIDVGQADAIFAMQRVVELRWDKVDIGVLRMIVESVIVQRLLIWMICAKFKAYRSETV-DMYENLGDWRYQARLILKSLMGKVREQLQER Mydma --------------------DCDGSSFY-------------------------------FLDVSHLKVQKILQIDLALTASLGKRTKFQENNLPQMINLNESPTDITLNDDTLLPHIKFIDYVNISPIDQAFILSTCLH-KSRPRDKLTVEEVMPYIECVLPKVWSIQYKCLYLRCLLEFASTRKMERSITQLEELHNTYVPEVSERQILMHSIGLQPIWKCEQSQAELLLSCGFTDSALEIFLRLHLWDDVI---------------------DIYEKAWTVSRSARAQRSIGLSYLMFAEAIPYLQKSLDLNCLVAFSLGCSCMATNQLDLATKALQQCC-SLDPDNSQAWNNLASSFIRLRALKEATRSYDNWKIWENFLLVSTDIGSEDSINCVNRLVELKRKTIDSEVLRILVDVVKLQKMFVMNVFPK------DLI-DIP---------------------------- Neucr2 VALSAFNTFLQINVT-GPSLDVDGVSVYQYILFGLARWVPLEW-LKLRVDVWHYKLITQLVEKAIQKAADVNKFQYMLSGALGKRTKFQEKATSQLVVLAKSPKAVELNDDTLLDDLQFTKQPQLSPLDQIILLTEAKD-AFSPSDSLTSEEVLPFAVRVISTNWQIYTQALLVRSRIEMHRSRTIERGVLQMQAVVDQVSAPAHVRLQYIHALSSPPRWHLESELAYSWAGVGSLVSALEIFKRLRLWAEVALCEKGKAIVRWRLPRLFCILGEMYERAWEISRYARAQKSLGEYWLQIFKARDAYRKAVVVNRMLWNRLGDISLRLGDFAEAAESFSRGIAAADNLDARTWSNLGSALYSLAAYKRGASANDNWRIWDNVITLASRVHPSEIILALNHIIKIRA--LDIAVLHLLLRECVVCELLLWKVIAFARAWRADYV-NLLKDHWKWKGKAKLAIRSVQRKARNELEDL Orpsp11 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANSVDAYKKALKINPLSWFILGCASMNIEDWDTAIEAWNRVI-SLESDHGEAWNNLASVYSKKKAFQEAIKRYDSPRIWMNYLYASIDLGENAAIKAMTQIVDQLYQKVDIEILEIIVNSISVENLLIFKICGNYKAYRIELV-EDYQNYGDWIYQSKMILRTLIGRTKDMLRDK Pench1 IGLAALFSFLQSNVT-GPDLTLDGEAAYKLTLFAVAKALLVAKTARVRTNFLHQKMLSELLERAIDQAAKVRRFEFALTGKMGKRTKFQDRDISQLVVLAKSPKNLNLDDDTLLEAISFSDQPILNPVDSALLLALAIT-NTSPENGLTREETNPYATRVLSSNWQIYTQALLVRSRVEGYRSRTVERAVLQMQALVDQVSAPAADRLEHIWILNFSTRWSLEAELAKRWVDLGGLRTALEIYERLHMWAEAALCGKAKNIIRRQLPRLLCILGDIYERAWEVSRYARAQRSLARHYLQLENAEIAYKKSLHINRLAWFALGCVQLELQKWQEATDTFTRTV-QLDDTDGQAWID--------SALQRAAQKGTDARIWDNVLTVAASIPPRDVITAQKRIIELLGAKVDVAILAMLVDFLNIISLVLWQIVARVKAWRAKLVRDGYAKFGDWRFKSRSAVRGIMGKGKERLKEL Phybl2 TGIACLNAFVQINWT-GPSLSADSEEVYHLTWLAAARKITAAF-WAQRAVFIQQQLLDESLEMGMTESQKASGFEWSLTGALGRRTKFQTFDVSQLVVHAESPETLELDDDTILDDVAYAKHGNLNIIDQCLLLAFCVK-NTNPDHGITTEEMNPYVVRVLINNWMVHTMALLLRTRLEAHKTRTVERSALQLQALVDQI-SGPEERLAYFYDLLLPSKWDMERELAGRFVSLGVVRSALEIFERLEMWEDVISCLKAKQVIERLMAKLWCILGDIWKKAWELSTFARAMRSLGSYYYNFPEAIECYKKALDINPLSWYVLGCAGMQAEQWDVAMRAFQRVV-ALDQEQAEAWNNLSSIYVRLLALKQATRKFDSWKMWQNLLYVSVDIGQSDAIWAMQRIVDMRWDKVDVPVLRLIVESVIVQRLLIWSICSKFKAYRADTV-DMYETLGDWKYQARLIVKGLMGKTRERLKER Picst3 VAIAFLQLYVQLNFT-GPLLNSEGQQAYDLMFLVISEVLSLQW-WRNRALQVHISIVSEFLEAALGHAKKLSQFNFLLSGAKAKRTKFQQFHTAALIILAKSPESFQLGDDLLLEKPQFESQPALSALDNLQLLLRLIR-QTTPSHDAVEQELMAIVSRIIGCNWTIFSRALWERSLLETSKARTVERGILQMTSLVEEILSPASSRLRFIHQLPLMPQWQMDAQLAEKYMSLGVVKSALEIYERLQLHCEAALCLQAEKILVERIVRAISILGDIWIKAWELGRYAKAKSSLSHYYYNLELALEHMHDCLTATPLNWFFYGCCGLESAQYELASEAFTRCV-ALDDTNSPAWSNLASSLIKLNALKKAIRENKNWRIYENYLTVSAKLNENDVLVASKELIEIRAKTIDINVYEKLAEILVCVDLICWRIIARVRAYRADLI-GAYESLGDWKYKSRTTVRSLMSKGKNRLQDL Plicr1 LAVACLHAFVQVNWT-GPELAYGGEPAYHLALLRLAQALSTPW-WNLRAAVVHEKILDEILEEGFVKAARATGLQYELTGALGKRTKFQQTDHSQLVLLAESPDTLALNDDTLLEQTEFTSQPALHPLDQCILLSLCVR-NTSPAHGLTSEQMAPYVTRVIPRNWSVHTMALLLRSRLEASRTRTAERSTLQLQALVDQM-STLAERLRYFHSIPLPSKWELEKELAMRFLSLGVVKSALEIFERLEMWEEVVTCDKAVSIVRDLLAKLWCILGDLYSHAWTISTSGRAMRSLGGFYFEFIQAIPYLKRAVAINPLSWFVLGCAYVREENWEGARDAFSRCV-AIDDEDGESWNNLASMYLRMRALKQGLKSYDNWRMWSNYMIVAMDVGESEACRAVGRVVEERSTKVDEDVLERLVDAVTVLDLFIFRAYARLDGYRCDIV-GVLTNFGKWKLQARSIVRTFVGRTKERLTAL Polpo CGITFLNLYVQINWTGGPMLELDGETIYTKVLLYLARLCSSCW-WSVRAMIYHQRSLDNKLEQSIEQAANISQLTATLTGALGRRTRFQTFDTAQLIVDVTKQREVTNDDPTLLSRPKITEVSNLRIVDQAILLVNALK-AKNGANG-ANEEMTPYVHKALPNSWIVHSMGLLMKSRLEANSSKTAERAALQIQALVEQYSASTALRLQYLYITDYPSRWDLEREVGERFVSVGAVATAYDIFERLEMWADAIKCARSEELVRSRLPELWCVLGDIYLKGWELSRYSRAQRSLAHHYLQWQEAIDCYQVALTINPLSWFSLGCAAMRLEKWDIATNAFSRCI-ALEPEEAEAYGNLAAVYMIQVALQEGLKRRENWKMWENFQHVCMVMKDQSAIQCILQIFELNNKKVDLGVLQVLANFVVISEMFVWRIYADYRAVRCVLI-RLYLGQETNIYSAKLKINGIMKKVEKKLQSL Pucgr2 FIATLLSVYVQINYT-GPALSLAGEPAYHLAYLLMAIQLTIVW-WKLRAEILRRQLFDQTLERGFRKAVTQAKLEYELTGIPGKRTKFQEKEISQLVVLAQSPVTLALDDDTLMEKTQFTQQPNLHPLDQALLLALSIK-NTSPAHGLTNAQMAPFVERVLPNNWSIHSMALLIRSRLEAHRTRTVERGLLQLQALVDQLKATALERVRCTWSLALPSRWELEKELGQKFSGLGLTRSAMEIFERLEMWEHVVQCTLGIELVRELIGKLWCLLAELWQTAWNVSTSSRAMRSLGAHHFDYPKAKECLLRALEINPLTWFIYGCAAMRTDDWDEAERAFRRCV-GLDDEDAEAWNNLATVHLKKYALQQAVKSYDSWRMYTNYMLIAMSVGEMEATRALGRVVEIRGEAVDMEVLAKLVKVIMLVDVILWELRSELESYRVRTI-QKLARLGNWKWQAKNLASNFLAKSKEDLADF Punst1 VAVACLHAFVQVNWT-GPELAYSGEPAYHLAFLRIAQILSAPW-WRLRAFNVHEQVLDELLEHGFVEAAQSTGMEYELTGALGKRTKFQQMDVTQLILLAESPETLALNDDTLLEHTQFTAQPALDPLDQCILLSLCVR-NTSPAHGLTQEQMAPYVARVIPRNWSVHTMALLLRSRLESGRTRLVERSVLQLQALVDQM-APLSERLLYFHDIPLPSKWELERELATRFLELGVVRSALEIFERLEMWEEVVKCDKAIKIVRDLLAKLWCILGDLYMKAWTVSTSGRAMRSLGGYHFRFAEAVSCLKRAVKINPLSWFVLGCACVRLEDWEGAREAFTRCV-SIDDEDSESWNNLASVYLRMRALQQGVKSYDNWRMWNNYMIVAVDVGESEACRALGRVIEERSSRVDEDVLDRLVDAVTVLDLFVFRAYARLDAYRCEIV-DVLRNFGNWRSQARSVVRTFMGKTKQQLVDL Rhior3 TGIACLNSFIQINWT-GPSLSADSEEVYHLTLLAIALTLTGSF-WSMRATFIQQQLLDEQLETGMESAQKESRFTWSLTGALGRRTKFQTFDVSQLVVLAESPETLDLNDDTVLEKIAFTEHGNLNVIDQCILLAFCVK-NTNPDHGITTEQMVPYVTRVLANNWMVHTMGLLLRSRLESNKGRTVERSALQLQALVDQI-STVQERLAYFYDLLLPSKWEMERELARRFVSLGVLRSAADIFERLEMWEDVISCQKAKQILQRLMPKYWCILGDLWRKSWEISHYARAMRSLGSYEFNYEAAIECYQKALEINPLSWYILGCAAMVVENWEVSARAFQRVV-LLDDEQAEAWNNLASIYTKMLALKRATRKFDDWRMWQNLLFVSIDVGQADSIYAMQRVVELRWDKVDVGVLRMIIESVVVQRLLIWMICAKFKAYRSETV-DMYESLGDWRYQSRLILKGLMGKVKERLKER Rhoto1 AAVAALHAYAQVNWT-GPELALGGEPVYHLSFAYLALQLSVKI-WRLRAGIMWLRILDETLTLSAKEAAKDAGLEWELTGRMGKRTKWQIDEKTQLVVLARDPEMLALNDDTLLERTSYTDQPSISPFSQSVLLSLSTL--PAPTSLMSTSQISAFVDRVLPQNWSVHSMALLLRCRAEAGRSRTVERGVLQMQALVDQLMASARDRLAQFHALALPPAWEMERELAVRYMSLGIVKSALEIFTRLEMWEEVARCDRGVDIIRELLAKLWCTLGELYEKAWEVSSSSRAQRSLGAVYFEYDKARESLRLALAINPLTWFMLGCCEMRLEDWKGAQEAFSRCV-GLDGEDAESWSNLASCHLRRQCLRQAIKSYDSWRLWYNYMVVAMDVGESEACRALDRMVVMRIEKVDLEVLEKLVDAVTVEHLLVFLAHARLKAYRATVV-SMLENLGDWKFQARSLVRTFLGRTRARLKEL Rozal11 RRIGCLFLFLQNNFT-GPELKCDGEDVLTHILLVEALRIYKKW-WMALILFTQQRVIENYLQRA---AQEMADFKWSFTGVLGKRTRFQTFNVSQLVLQTEKPRNLDLNDDTLLEKMKPENERKLNPLEQSILITNCLK-SKRAKDDILVEEMLAFVRRILSTHWIVYSMALLQRSRLENNKTRTVERSVLQINALVDQYETPSHKRLYSIFNVLYPNKVSLEEELADSFLNLGLIKSALEIYERLELFEGMITCSKAEELLNRRIYKALFYLGELLIKSWEISKYSKAKRLLGQQAFKFQECISHLQEALKVNSLTWFLLGCAAMRVDEMEIAKEAFVKVV-SLSPDNGEGWSNLAAVQQRQVSLRQALKSFDNWKIWENLLYMSINTGESDALLALKRIFELKENFVDVQYLDVFISEALTSQFLIWEISAKFKAYRCSLV-TILMEFKEAIYQSQTLLRSLIKKSESQLQEL Sacce1 LAIALLQTFIQNNYT-GPSLAIMGQPAYEFMYLVLSLLLVAYW-WWARALLTQLSLIPEYLENVLTRAKKITNFEFVMTGARATRTKYQQKAHAGLIILAKSPETFALESDLLLEKPHFESQPTLSDYDNIQLLLRLIK-NTTPAKDPVEEELTALLSRILK-NWSIFARSLWERSIIETTKAKTIERGLLQMQSLVEELI-NVASRLSYIHQLPFIPRWQLDATLAEKYMSLGILKSAVEIYERLGMACETALCKKAEEILLQRIARAYSILGDIWEKSWEIGKYVNAKNSLAKYYFNYSATLKHLNDSLRQYPLTWYFYGCVGLQCGKMQIAAEAFTRCV-SLDPYHALSWSNLSAAYTKMSCLKRAI-AQKNWKIWENYMLVAVKLNEEDVLTACKQLVSIRRDKIDLPIIEKLVELLVCTEFICWRLVARVKAYRADLV-AAYESLGDWKYKCRSTIKALMSKGKDRLVEA Salro FGVAALLAFMQDNWT-GPCLSADGEQMYAWVLLLIARTVAAAA-YELRALRAHQEMMEQFLETALDRAQTTLDMEVALTGALGKRTKFQVKSLPQL------------------------------------LLAIS-K-STNAHH---------------PEPTSPPEQ--LPKTRLDKLKSRKLQRSTEQLAVVSNLFAPDARGRLHNIFSVSLPPYWQLQRELAQRYITIGLHRDALVLYERLELWEGVITATTAEAIVRARLASLWCALGEIFTKAWEMSRLTKAMRLMGLMLLKYKRAMDCFEKCLKLNSLVWFSLGCAAMRIDDHATCTRAFRRKV-EIDDSDFESWNNLANGYVQLFAFHESTKAFDNWKVWENYSAIAVDVCASETIRSIHRLMELKSAYDDWQVLAALTQGVLLAEVMVWLVAARFNAYQLDMV--------KEMNSCKLMIKGVAKTLSEEMQQL Schco3 LGAASLHAFVQANWT-GPELAYGGEPAYHLALLRLAQLSTRAW-WRLRTTLIHAQLLDERVEEGFERAAEATGLVYELSGALGKRTKFQQNEVSQLVLLAESPDNLALNDDTLLEQTEYSSQPALHPVDQCIVLGLCHL-KAAPSHSLTIEEAKPYVARVIPRNWSVHTAALLLRSRLEASRTRTVERATLQLQALIDQM-ASNAVRLRYAYALPLPSRWALEREVGLRYLSLGVVRSALEIFERLELWEEVVQCSVATAIVRDLLAKLYCILGDLYEQALHLVRSSRALRSLGYLAFGFREATAHLRGAVAINPLAWFILGCAYLRIEDWLGAREAFSACV-RIDDTDPESWANLAAVYLRLQALKQALRAHSNWKIWANYMVVSVEVGESEAARALARVADETSGQIDPDVLDRLVGAAVVRSLFVHRAHARF-----EIV-DVLRNVGKWKLQARSLVRAFIGRERERVEAL Schpo1 --IQMLEYFIQNNYT-GPSLTVEGERPYRLAFLLLSQTLLHIW-YKARLDFLHQQMLKETMEMGMKESAKVMDFHFELTGALGRRTKFQTFDTSQLVVLAKSPITFELNDDTLLEKISFKEPSKLDPLDASLLLAFCIK-NNNPDDGLTREEMAPYAERVLPVNWSVYTMALLVRARLEGFKSRTVERSVLQMQALLDQLSASLKERLNYFYNLLMPSRWQLEAELAERFISVGATKSALEIFERLQMWDCVVMCDLAVQVIKREL--LRTLLGDIYVEAWELSRFAPAQRSLGKYYYDLLQAMNCFNESLKINPLTWFTYGCAALELQKYDAAMEAFSRCL-SINPEDGESWNNLASAMLKAHAMQQGIKMYDNWRIWENYMLISVDVNKSEVIRALRRIIEIKGKDVDVQCLDLVVNYVMLNELLLWRIVARYKAYRIELV-EAYANLGDWKFKSRSVLRSLIGKGKQKLESE Sorma VALAAFNAFLQINVT-GPTLDVDGVS------LGLGQGLPLQW-LKLRVDVWHYKLITQLVEKAIQKAAEVNKFQYMLSGALGKRTKFQEKATSQLVVLAKSPKALELNDDTLLEDLQFTKQPQLSPLDQIILLTEAKD-AFSPNDTLTAEEILPFAVRVISTNWQIYTQALLVRSRIEMHRSRTMERGVLQMQAVVDQVSAPAHVRLQYIHALSSPPRWHLESELAYSWAGVGSLVSAVEIFKRLRLWAEVALCEKGKAIVRWRLPRLFCILGEMYERAWEISRYARAQKSLGEYWLEIFKARDAYRKAVVVNRMLWNRLGDISLRLGDFAEAAESFSRGIAAADPIDARTWSNLGSALYSLAAYKRGASANDNWRIWDNVITLASRVRPSEILLALNHIIKIRG--LDIDVLRLLVNEAVVCELLFWELLVRVRAWRAQLV-TLLKDYGRWKGKARLAIRSVRGKAKNTLVDL Sphar VGAAALNTFVQTNWT-GPCLGADGEEAYGLALLLIALAVSAHW-WYSRAVFKQQQILSDLIEMAIIDARELAGVTLELTGALGRRTRWQQTDISQLVLRASGPKKLALNDDTLLEKIAFNEKSSLSVLTQCLLLASCVK-NSNAKDGLTTEEMVPFVERLLKHNWQVYSMGLLLRSRLEGERNRTAERGAMQMQVLVDQF-ASPAVRMAHIYTIYYPSRFELEREIGIYYLRLGVVVSAREIFERLHMWEDVVDCEKAVAMATELVPRRLCLLGDVYQRAWDVSRYSKAMRALGRIHFEFAECVECLQKAADINPLVWFTMGAAAIRIGDWESGIKAYRHCV-TLNDTNGESWNNLGTCYIRVSAFKYAAKSYDNWKVWENYFNVNLQLKLNECIECMNRLLDLKGNKTDVKAMQYTNDAVMWQETLIWNISAKWRAYRSKIY-DVYEAKGKGFHSALLMLRGLVKKTQPKLEAA Spipu1 VGVACLYAFLQSGWT-GPNLVEDGEEVYSLTFLVYAKVISTSW-WRARTLFTQQKLLENNLELGLEAAQAASRFKWTLTGALGKRTKFQEFDVSQLVVMAESPKTLALNDDTLLETIEFTQQGNLKVIDQCILLAFCVK-NTNPAHGLTTEEMLPYVRRVLANNWMVHTMGLLLRSRLESNKSRTVERAALQLQALVDQF-SSVSDRMLHIFSIMLPAKWEMERELAERFVSLGVTRTALEIFERLELWEDVISCKKAEALVQERLPKLHCILGDLYEMAWKLSRYARAMRSLGAYYFEWVKSIECYHRALAINSLSWFVMGCAAMRAEDWDQAVRAFSRVT-SLDHENGEAWTNLASVYVRQRALREAIKHFDNSKIWENYLYTSIDLGEQEAIHAMERVLDTRWDKVDVEVLDILVNAVVLNRLLVFSCVAKFKAYRCELV-DAYVTDGDWAYQARMVLRTLIGRTKDELKGK Sporo1 IGVAALHAYAQVNWV-GPSLAFAGEPLYHLSFLHLALQISIKI-WRLRAGVMWIKVLDETLSLSARAAAQEVGLEWELTGRKGKRTKWQVDEKTQLVVLAKDPENFALNDDTLLERTAFTPQPTISPFSQTVLLSLATL--PAPTSLMSTSQISSFVARVLSQNWSVHSMALLLRCRAEAGRSRTVERGVLQMQALVDQLMADARDRLVQFHGLALPPAWEMEKELAVRYMSLGIVKSALEIFTRLEMWEEVARCDRGVEIIKELLAKLWCTLGELYERAWEVSSSSRAQRSLGAVYYEYDKARTALRLALAINPLTWFMLGCCEMRLEDWAGAQESFGRAV-GLENDDAQSWSNLASCHLRRQCLRQSIKSYDSWRLWYNYMVVAVDVGESEACRSLDRIIGMRINKIDFEVLDRLVDAVTVERLIVFLARARLKAYRSEVV-EMLENLGDWKFQARSLVRTFLGRTKEKLKEL Stehi1 VAVAFLNAFMQVNWT-GPELAYGGEPAYHLAFFRLAQILTIQW-WRLRTWNVHEQLLDEWLERGFLRSARATELQYELTGALGKRTKFQETDHTQLILLAESPETLALNDDTLLEQTEYTSQPSLHPLDQCILLSLCVR-NTSPTHGLTNEQMSPYIARVIPENWSVHTMALLLRSRLEAHRTRTVERSTLQLQALLDQM-SSPRERLLYVHSIPLPSKWEMERELALRFLSIGVVKSALEIFERLEMWEEAVKCDKAINVVRDLLAKLWCLLGDLYTHAWEFSTAGRAMRSLGGWHFEWEETAECLRKAVAINPLSWFILGCACVRLQDWPGARDAFARCV-ALDEEDGESWNNLATVYLRMRALKQGLKSYDNWRMWSNYMIIAMDIGESEACRALGRIVEERAAKVDEDVLDRLVDAVTVEDLFVFRARARLEAYRLEIV-EMLRNFGKWAVQARSILRTFMGRARVRLEEL Tapde11 LGVSLLNAFLQVNYT-GPHLVVDGERPYPLVYLALASRIQALW-H-VRVSFVHQKLLDDHLELAVQEAQRTSGLNMKISGALGRRTKFQTFDVSQLVVLAKSPLELDLDDDTLLENVSFSTQPQLSLIDQCILLTYAIKISAASDDQIIIEQVAAYIARVLENNWTVNSSALLARTRVEGHRSRTVERSVLQLQALVDQLSAPAKERLMPLFCLPLASKWDLQLELARKYTSIGLVRSALEIFERLESWEQVAMCDKAESILRTQIPKLWCLLGDVWEKSWQVSRYARAQRSLGKWHFEHQRAIESYAKSLKINPLAWFYYGCAGLETNQFEVAAEAFTRCI-SIDQTDGESWNNLASALLRLQALKTATDKYDSWRMWENYMLVSMDLQEGETVRAMRRCIDIR-RDVDLDVLQLLVQHVLVYDLLLWRILGKVKAYRCELT-DAYRNLGDWRFKSKSVVRSLKARGGQRLADL Thetr LGVAALTLFVQANWT-GPLLGLDGEDAFDKCYLVVASLISAVV-WRARVARARQSTLLATLEAALLHAQALSGLVIALRGAKGKRTKFQKFTTTHLYVSAQGPFIVPNDSPVLLEELTFETEPAVSLDDAAILLALAIR-ATHPVSELTDEQVRPFARRALQASWAMRAAGLLLKSRVEMRGKRTIERACKQFQRLVELRGPAPAERMAYLFALPLPPWWKLLSELGSLYMDHGLPRAALDCYEPMEAWEDIVTCSRAERLVRARLPRLWALLGDLYERAWRESRFPRAQRAWGKLAFDYAGAIEHFELALAINPIIWFSMGMASMFAQAWEVGSRAFSRVV-QLDPTHGEGWANLSGVYQRAHAMEQALKKREAWRMWENFLYICMQLGEEQAMQALRNKIQYNNAQADPRVLYALVTHLNLTNLFVWDAHAQLKRARAALA-TELDDIETLRPSILLLLNSVVARSEAELVEL Treme1 IAIALLHSFIQINWT-GPFLTLNGEPAYHLVLLVLSLRLSISW-WILRAHMVHQSLLDEELEIGFLKAAKESGLEFELTGALGKRTKYQVEEHSQLVLLAQSPQTLPLNDDTLLEETQFTKQPPLHPLDQSLLLSLCQH-NSSPSHGLTSSQMMPFITRVIPDSWSVHTTALLLRSRLESNRSRTVERSALQLAALIDQM-STPSERLRWFHHLPLPSKWEMERELARRYLSLGVMRSALDIFTRLELWEDAVLCKEAISIVKDLLARLWCLLGDLYWKAWEISTSSRAMRSLASLKVDYEGSIECFKFALEINPLSWFTLGFCYMKLERWEEARDAFQRGV-GVDEDDAEGWNNLAAVYLRLRALRQGLKSPTNWRMWQNYMFLALSVGEVEACRAMMRLVEDFGGKVDFDVLDKLVDASQLSLLFIYKSHSRFRAYKCEIV-ETVRV--NWKLTARNIIRTFMARTKEQLRQL Trire2 IGLAALDAFLQATVT-GPYLEVDGVAPYAYILFSLAKYISLAW-ERLRVNVWHYKIITQLIEAALKEAAKTTGVTYALSGALGKRTKFQEHSLSQLVVFAKSPDALKLNDDTLLEEIQFTKQPQLSPLDEMILLTEAKD-AFSPVDDLTSEQILPFATRVLSVNWQIYTQALLVRSRIEIHRSRTVERGVLQLQAVADQVSAPARVRLRYIHALSTPPRWHLESELAYAWAGVGSMTSALEIFKRLKLWAEVALCDKAKGIIRWRLPRLWCILGDLYERAWEISRYARAQRSLGEYHLDLFKALEAYKKATSVNRLMWGRLGDISLRLGNFEDAAEAYSRSIGCANDTGARTWSNLGSALYSLAAYKKGASAHDNWRIWDNVVTLASRIHPADMVLALSQIIRIRK--LDANVLAALLQDAIVIRFVLWTLVSRLRAWRAELV-SVLENWGKWKGKARSAVRSVMGRGKRTLEGL Umbra1 TGIAALNIFIQVNWT-GPYLSADSEEVYHLAFLAIALAISAAW-WYARALFTQQKLLDEHLELGFQVSQQSSGFNWNVTGAMGRRTKHQQFDVSQLVIVAESPETLALNDDTLLEKIAI--QGNLQVIDQCLLLAYCVK-NTNPDHGMTSEQMVPFVSRVLPNNWMVYTMALLLRSRLESNKSRTVERSVLQLQALVDQI-STVQERLAYFYQILIPSKWEMERELAKRFISLGVMRSALEIFERLQMWEDVISTDKAKKILLTLLPKLWCILGDIWHKAWEISPFARAMRSLGAYHYEYSDSIACYENAMKLNPLSWFVMGCAAIQISEWDVGIKAFSRSV-ALDDENAEAWNNLASIYIRQYALKQATKKFENWKMWQNLLWVCIDIGEAESILAMQRIVDIRWEKVDTEVLSLIIDGVTVQNLLLWRICSKFKAYRSDTV-DMYENFGDWKYQARTVLKGLIGKAKDKLKER Ustma22 IAVCALHAFVQINWT-GPALAFKGEPAYHLCFLVLSKLVTLAW-WRLRVFTVHSHVLDQILERGFVNAAKENGLRYRMSGALGKRTKFQKEDKTQLVLLAKSPSTYALNDDTLLEQTKFTSQPPLAVLDQCTLLALCIH-NTQAAHGLTANQMQMFIARVVARNWTVHTMSLLLRARLESTRTRTVERSVLQLQALIDQM-SSIQERLKFFHALDLPPKWEMQAELARRYASIGVTRSALEIFERIEMWEEVVQCQEAVEVVSELLAKLWCLLGDLYSKAWQVSSSARAARSLGGVYFDFGQASKWLRYALKINPLSWFILGCCYMRLEKWNEGAQCFRRCT-ALDDEDMESWNNLASCYLRMRSLQQSLRAHDNWRVWYNYMVVCVDVGYLEATRAMVRVTEIQTRNVDVGVLARLVDAVTVQRLFIWKLYSRLDAYNSNLV-DALLDLAEPRFQARSLVRSFLAKTRDQAKEL Walse1 VAVALLHSFIQINWT-GPKLSTGGEPAYHLTLLLIAQAISAKW-WNLRAAVAQQHLLDETLEVGFLEAANTNELKFHLTGALGKRTKFQQSDITQLVLLAESVKDLELNDDTLLEQTQFSSQPKLSAIDQCILLGMCIK-NTAPENGLTNSQMGAFVQRVLHQNWSIYTMSLLLRSRLEAHRTRTVQRATLQLQALIDQM-SSNVERLKYFFAMPMPAKWELERELAQRFVNIGVVRSALEIYQKLEMWEDTIICNDALDTVKGLLAKLWCLYGDLYKKALEVSSSSRAYRSLGGLYFDSKSTIEVLRKAVAINPLTWFILGCACIRLEDWDGAIEAFSRCV-AIEDDDAESWNNLASVYLRLRALKQGSRGFDNWRIWQNLMIVSIDVGEADATRAVGRLADIRGELSELDVVDKVVDAVTVDRLFIFKSYARLKAYRADLV-DVLQNFGDWKYQARSLLRTFLGRTRAQLKEL Zygro1 LAIALLQTFIQNNYT-GPLLSSGGQPAYDLMLLILSLILVAHW-WRARALVTHLSLLSEYLENVLTKVKKLTNFEFVLTGARAIRTKFQQKSHSGLIILAESPENFTLQSDLLLEKTHFESQPKLSNYDNIQLLLRLLR-QLSPAKDPVEEELGAVIYRIIK-NYGIFSRALWERSVVETLKARTVERGLLQMQALVEELTENPPSRLKYIHQLPFIPRWELDTLLAEKYMSLGVLKSAVEIYERLHLACEAALCRQAETIILNRIARAISILGDIWEQSWQIGKYVNAKNSLAKYYYNLGAVLRHLNDSLRRYPLTWYFYGCVGLESGKMELAAEAFSRCV-SLDPTHGAAWSNLSAAYVELSCLKQAV-ARKNWRIWENYMLVAMKLNEQDVLMACKNLVTIKRDRIDLPVVEKLVELLICIDFICWRIVARVKAYRADLV-AAYESLGDWKYKSRATIKALMSKGKERLLEM [Cluster2189.fasta_al_trimmed; alignment length = 331] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 QLEELVSFLH-SPQPAVKQIALDNLVGFSTG--PE------------NYRPIQDLKELAK-NKTIVQQSVTILANLCDDPVMIDFLSYLADLGNSSADIMC-ILLSNLAKEGI--TNIFGIN-----FMSK---NVIDCLMDCFVKGKLNQ------YANFDYLSFFFADISRKGRNYFVEEQQPISKLLVFTEKYDNKTRRLGVASTIKNSLF--------------DEK-INLLPYILLPIAEL-DEEDLF-NLPDEL--QFLPEDKQRDPVPEIICVHLESLLLLCTTANGREYLRSKSVYPLIRELHELCHRIVNMLMRG-ESKSAE Aspfu1 ---------------------------------------------------MQHAKTLLA-S-PIRTSSNVISFSQCA-------ISSFWSYGEDN--------------DKL--SRLITLK-----STST---MAIDQLMDCFVKGALNK------KANFDYLSYLFADLSEIGRAYFTTRQDPVTKLTVFTE-HESTVRRKGVASTIKNVAF--------------ADD-ANLLPYVLLPITEF-SEEESM-AMLPDL--QLLPPDKRRDGDNSIIVTHLETLLLLTTTREGRDKMRAINVYPIIRECHEACDRLVQVLMRD-ESSKSD Aurde31 ELRELFQFLH-DRNPNVRQIALQNLLGHTPQGSTDAT-------------AIRDLKILCR-D-AIAHDAFRALVNLSDAPQLREFLAFLCYPPSILADLAA-MILSNLTAPGP-SETLLELNIPVI-SATSIPPKALPLLVAAFADA------EGTRKADLNFLASVFANLSPAGRVFFLTP--PLAKLVAFAE-HKDTIRRGGVISTLKNCCFPDSEQVTVPPSTTPAPG-IDALPYLLLPLAEF-DLEDQE-KMPAAL--QFLPASKTREADGALRLMLVETLLLLCTKRWGRDFLRAHGVYEVVRAMHEHVERLVNLLKRD-E----- Batde5 ----------------------------------N------------DFKPVKDLMKLTT-D-LTAHDAISALVNLSKDPAIDAFLTQMILPKNINADLCC-MLLNNISKEMV-AKKLLVAV-----SESLPSDHRIDNLLEIFVRGTYNP------EASFHFLGGVFANITPHGCQFLLSRSTRMSKLVVFTE-HKDVIRRGSVVSAIKNCCF--------------D-E-LNLLVYILLPLSDY-TTEEME-GMPDEL--QLLEPEKKREPDSKIRLMLVEIILLLTSTRFGRDRMRALQVYQVIKKLHSVIEEIVNMLMRD-EHIEPA Botbo1 QLRELLAFLH-DRNPQVRQLALSNVLGYTPKGSEGLS-AGGLKPGSGETQVIRDLKLLCR-D-AIAHDAFKALVNLSDSPLLRSFLVFLVHPASVLADLAA-MILSNLSAPNV-PKAILSLVIPILACPTSPPPSALSLLVDAF---EPDGT-KLDRKGELHFLSSVFANISPPGRSFFLTPMPPLAKIISFTE-HPNLMRRGGVASTIKNCAFASEEKIIIPPATVAAPA-INALVSILLPLAEF-DLEDTD-LLPPAL--QFLPPTKTREIDPVLRLTHVETLLLLCSTRWGRDHLRANGVYPIIRVMHEHVERLVNFLKRD-EAVPQD Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel SVDDLVKLLSPTMSLIVRRKTMEVVTQLGTPLDGQ------------DFALGKAICQLCE--SSDRTETLAALTNFTSGSIESKCVEIAY-TNALYSSVAS-RLLVNVSRDRV---------------------NYIGQLLNEIKKS------TGD-EDRAKFVGFTVVNLSPPIRQNIVQGGEIVCELLTTAE---TTEIRECAADVLRNLAF--------------TS--DEYLCSILAPLMNL-DEEEIA-KLPVRL--QYY--EKERDSSDIVRQKLIEALFQLCATKHGREVLRAKGVYPAMRELDHTLHALIGILIRY-EDVDPE Canalb1 ELEELVSFLH-SPQPAVSQIALDNLVGYSTG--PN------------NYEAIKDLKNISK-SKTLVNQSVTILANLCDDLVMEEYLKYLANIKNTNADLMC-ILLTNLAKDAI--NKVLDFE-----FSSK---KVIDCLMDCFVKGKLNE------YANYDYLSYFFADLSKQGRTYFITEQSPLSKVLVFTEKYDDKIRREGVASTIKNSLF--------------DPK-INLLPFILLPLAEI-DEDEMF-DLPEEL--QLLPSDKKREPLSGILCIHLESLLLLCTTREAREYLREKQVYAIIKELHDLCDRVVQMLKRD-ES---- Cangl QLEELVSFLH-SPQPAVRQIALDNLVGFSTG--PD------------NYRALDDLKVLMK-ERTLVQQSATVLANLCDDAVMKEFLEYLTDLGNTSSDIMC-ILLSNLSKDSI--TYVFEIV-----FKSK---RVIDCLMDCFVKGELNK------FANYDYLSYFFADVSKIGRTYFIETQEPISKLLVFTEKYDSKTRREGVASTIKNSLF--------------DEE-INLLPYILLPIAEI-DEEDMF-NLPDEL--QLLPEDKTRDPVPSIVCTHLESILLLCTTKAAREFMRSKSVYPLIRELHELCYRIVNMLMRG-DAKSVE Capow ALEELADFLK-DSRSLVRAHAVDTVAGLTASADG-------------YPRLADELLARLS-DPGIARDAFKAVVNMTGDRTLPGLFAHLVEPTSLFADLAA-MVLSNLTRNELGCGKLLGTNTP----------QALYKLVDVFCKG-FNHN-----NASLNFLAPILENVSNLGRRLLV----VLPRLLTHLE-NPDRVRRGGVAGIARNCCF--------------EK--VDILSFLLLPLCEF-DDEDMD-GMPDCC--QYLDSSKQREPEVSIRRHLVEALYQLCATKHGRTVLRAKKVYPIIREMHKACDHLVQVLVGE-EPLPES Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHLLLPLAEF-DDEDND-RLPLDL--QYLPSDKQREDDPDVRVILVEALTLLCATQSGRAYVKAKNTYVIMRELYETCEKLVQILISD-EDIPEE CocheC53 ELEELVEFLH-HGNTQIRQTAAEHLVGYSQS---N------------QLEPIKDLKLLVK-D-PIAKNALTILINVSADAEVDEFLETLLNAKEQNANEIA-MLLANMAKDSL--QRVLELK-----SKSA---WAMDQLMDCFVKGAYNK------NADFDYLSYFFADLAPKGREYLTSPQEPITKIQVFTD-HASHIRRLGVASTIKNVAFPDPNL---PP---PSIG-ANLLPYILLPLMEY-ADEDTE-GMLDEL--QLLEPDKEREKDNQIIKTHLETLLLLSTTKESREVLRRVKVYPIVRECHEACDRVVQVIMRK-ESAGGS Coere1 QLDELVEFLS-SSRPDVRQLAATYIVDFSNPSSDR------------VDKLIKPLLVICH-E-VVASKAMNTLINMSTDLDVEDMLAMIVSSECYIADPAC-MLLSNLTKDDV-CQELNSLQVS---CNSS---MALDQLTDVFVKGKYNK------NATYSFLASVFADITSFGRRYFLERTSPITKIMVFNE-YPEVIRRGGVDSTMKNVCFP-------------KE--TNMLPYILLPLCEF-DMEDME-AMPEEI--QFLGDDKKREPDPKLRATLLEAINLLCTTFYGRNVLRSKNVYYVLREAHDLNERAVQLIKGD-E----- Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 QFEELIPFLR-EKNPQVRQLALSNLLGQTPQGSPGLSGGGGLKKPQ-ETEVIRDLKLLCR-D-AVAHDAFRALVNLSDSPLIPSFLAFLVHPDAICADLAS-MILSNLSAPAV-CAAILTLKVLVIPSGTCAAPLALPLLLDAFVDAELSG--KETRKAELHFLASVFANISPAGRLFFLTPWPPLAKIVAFTE-HKDTIRRGGVASTIKNCAFPESEKVAVSPSTQAAPG-INALPYILLPLAEL-DLEEQD-RLPSEL--QFLPPTKTRERDEVLRLTHVETLLLLCTHRWGREYLRAHGVYEIVRGAHEHIERLVLLVKGD-EEVDE- Copci QLRELVPFLR-DKNPQARHLALENLLPQTAQGAPGLG-GGGLQKAK-ETDIIRDLKLLCR-D-NVAHDAFRALVNLSDSPALPTFLNFIVNPHSICADLAS-MLLSNLTASVP-CNAIINMKISVIPSGSCPTPAAIPLLIDAFVQGGEIS--DLSRKGELNFLASVFANLTPAGRVLFLKAQPPLAKIVPFTE-HKDSIRRKGVASTIKNCCFPETEQVAVKPSKVLAAG-VDALPYILLPLAEF-DLDDQE-KLLPAL--QFLPPEKKRESDALIRLTLVEALLLLCHTRWGRDYQREHGVYEIVRALHEHIERLVVLLKSE-EEEDV- Croqu1 QFEELIEFLH-DRNPEVRRLAVHALLPYTAASNPS---KSLRKAGQLKPTILNDLKNLCE-D-ITAHDALSALINLTDNDTVTDFLTFLLDPSAILADLAC-MLWSNLTKNSV---CLTCLKLPLVGERSIREKPMIDLAVELFARGKFNK------HANFDFLASVWANFSTDGRHYLLGRSPPLAQITPFTE-HPSVIRRGGSISAIKNCCFP-------KPDG------LDILPSILLPLCAF-DADDEE-HMPLEI--QMLGSEKKYESDAAIRTILVETLILLSSTVELREYLRRKRVYRVVQVLHEHVERLVNLLMRD-ESVQCE CryneH991 SLTELFQFLD-SPNPSARHLALQNLIGHTPKNSTKDG-SDE------KIKALKDLTYLCM-D-PIAHDALSALINLSDNPVVKEFLVWLVNTTSPLSPLTS-MLLSNITSPSL-IPNLANLTIPIIPASSTIHPEAVRALVQAFEDGGVKE-----RKGDCNFLASVFANISPVTRQLLLTPRPLLSKIVVYTG-HPDTIRRGGALGCIKNCAMSEEDRVRL------SDG-VDVLPWVLAPLMEY-DIDEMD-KLPPTL--QFLPPEKERERDPVLRMMCVEILLLLATTFTGREALRNRGAYYVVREHHDSIERLVGLLQRD-E----- Crypa2 ELEELVGFIA-SPDPRIRAVAIENLVPYSAS---N------------ELLPIRNLKVLVQ-D-QIAQHALTILVNLAADTQIDRFLAVIFNPSEPNANLFA-MLLANLAKDGL--KNILDRK-----GSDE---LVMNQLVDLFVKGSYNK------DADYDYLAYLFADLAAEVRQYFVTRQGPLTKLKVFTE-HKSEIRRKGVASAIKNVAF--------------EDE-IHILPYILLPIMDY-DPEEML-EMLPEL--QLLPPDKERETDPTIIQTHVETLMIFTTTRKGRDHMREIKVYPVVRETHVACERLVQVLMLD-DEL--- Debha1 ELEELVSFLH-SPQPAVIQIALDNLVGYSQG--AD------------NYEAIKDLKKLAQ-AKTTVSQSVTILANLCDDLTMEEFLKVLVNTKNSNADLMC-ILLTNLAKDSI--TKVFDFD-----FKST---KAMDCLMDCFVKGSLNK------YADYDYLAYFFADISLQGREYFITEQSPISKLLVFTEKYDSKIRREGVASTIKNSLF--------------DEK-INILPYILLPLAEL-DEDDMF-NLPDEL--QLLPSDKKRDPVNALICIHLESLLLLCTTREAREYLREKSVYPLIREMHDLCDRLVQMLMRD-ESSDDE Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi QLPELVPFLL-EPKSEIKLLALQHLLGVSDN-QE-------------STQIINNCIKLIT-DHVVVRHALTILINLCQDTDMKNIVPRLVDTKNKMSEIFA-MLLSNVTHKEG-CLSLMQCG------------FFIMKLVQVLTMD------QEDKSTKNNWIVNIILNVTQEGRKIVLDKE-IFKEILPLVR-HENVIKRRGILGIIRNCCY--------------PE--VDILTKLCLPIRKL-DDDDLV-GLHIDLHNSSLPIGNERDQDRECRKMVVESLIFLTGTKKGRVSMRTAKIYPILRNLFDNVEKVVELIIRD-EQMN-- Dmel -VKELVQFMQPNQRLDLKAVALTHVLGLTGSSEG-------------LDEMLMAIFGLTF-DQTVAKDAVLSLINLTSEEEAEVAAKEITNEQSDLADPWS-MVLSNLTRESL-VHEILDTLERDDH--------TLPRLAKAFAQL-YNKK-----KAKLHYLAPIFCNLTSRGRELCCHRKYLLEKLLPFASFEGSVVRRGGTIGILKNVCF--------------EQ--SSILVAILQPLCEF-SDEDNE-LLPIEL--QYLPESKTREEDPDLRKMLLECLLQLCSTRRSREILRSRGVYEILREYHLACENVVDILIKK-EEVPAE Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba QLWEAIKPLDKTPNMQYLNTLADILLMYSGQTDVH---QGA------AFRLLEKYIILPK-GASAHEKMISVMVNLCALLNTESILSLIQKPYTDYSPFKCSMLLANMSADKL---AVMHRR-----KGTD---RHMQLLLGQLTQLKFKDL-----LTFASHLAWTLVSMLMDMRPYILELLEPYAEVQFAAALSGA---RQSIIAAIKNLLFPAPA----DPRKVTPS--AALLRFVALPSDEW-D------EAPEWM--RALPEPTTRESDPSVRLLILECLLLLAGTRAGRVRMRDGSVYPVIREMHETIEGLVQFLGGDQETTPAE Fomme1 QLVQLLQFLH-DKNPQVRQIALANLVGHTTKGSLGLG-AGGLSKDN-ENDCIRDLKLLCR-D-VT-------------------------------------------------CSTLLSLKIPVIPSGTSPSPQALPLLVQAFSQSSA----PTERKADLHFLSSVFANLSSSGRSFFLTPRPPLLQLIAFTE-HADTIRRGGVASTIKNCAFPETEAVAVPPSNVEAPG-MNILPYILLPLAEF-DFEDQE-KLPAAL--QLLPDTKKREQDAVLRRTHVETLILFCTTRSGRDYLRNNGVYEVVRTLHENIERLVNLLKGD-ENMDS- Fusgr1 ELEELVGFIA-NPNAQIRLLAAENLVPYSLS---D------------KLQPVKHLSFLVR-D-KIAEHALTMLVNLSGDEEVEKFLGIVFNPEEPNANLLA-MLAANLSKDGL--KDFLKRK-----GSDE---IVLNQLLDLFVKGTYNK------NADFDYLAYVFADLSDDIRKHFLQEQAPLTKLKVFTE-HKSDIRRKGVASTIKNVAF--------------EDE-IDILPYILLPIMEY-DVDETM-DMLPDL--QLLPPDKKRDSDHQNIQTHVETLTLLTTSREGRDLMRRVKVYPVIRETHEACERLVQVLARD-EEGKPE Galma1 QLRELVQFLR-DRNPQVRQIALENLLPQTIKGAPGLQ-SGGLQKPK-ESDIIRDLKLLCR-D-SVAHDAFRALVNLSDSPLMPSFISFITNPHSILADLAA-MLLSNLTASTA-CSILLTLNVPIIPCGSCPAPLALPFLIDAFVEGVESG--DLSRKAELHFLANVFANMTPVGRNYFLSPQPPLAKLVAFTE-HADTMRRGGVASALKNCSFPESDAVAVPPSKATAPG-IDALPYILLPLAEF-DLDDQE-KLPEAL--QFLPPTKKREPDSTIRLTHIETLLLLCHTRWGRDYQRQHGVYEIVRAAHEHVERLVQLLHGE-EDLSTN Ganpr1 QLEELFPFLR-DPKQEVRKLAVEHVLSFS-TSQQS------------KKTVVRDLKKLLT-D-LVAHDALKSLINLSLNAPIESYLITLVVPTSVLADLAC-MALSNATKSEI-AAMLVKGR-----GKTT---SHVAALVDVFVKGKYNL------KAEFNFLANVFANVTSEGRALFLAEPPLLADLAPFVE-HPDIIRRGGVISTIKNCLF--------------PSGPYNLIPRLLLPLADL-SEDPQSLDLPPEL--QLLEPTKAREPDPVLRRMLVECLLLLATTREGRDVMRGCATYLVIREAHEEMEKVVDFLMRD-E----- Gloin1 QLESLFEFLH-DNNSDVRQIALKNLLEYTISTSQN------------NMRPIIDLKNLCK-D-VTAHNAYKALVNLTSDDEIENFLKYLMNREAILADIAC-MLLSNITKELI-CVKILSLN-----SNST---RAMDQLVDVFVKGKYNK------EAEFHFLASVFANVSPQGRRDFFLSSAPISKLIIFTE-HSNIIRRGGVISCIKNCCF--------------EEK-INILPYILLPLCEF-DTDDME-GMPDDI--QLLPPEKKREPDSHLRITLLESLVLLTTTKQGRDILRQKKVYPVIRQMHEIIEKLVNLLMRD-DESQL- Hisca1 ELAELVEFLH-HGNSQIRQIACENLLGFSIS---H------------QLLPVRDLKLLVR-D-PISKNALTILINLSGDEEVDAFLETLLNKKEPHVNEIT-MLLANLAKDSF--KRIINLT-----SGSP---KALDQLMDCFIKGGINKA----TDSNYDYLAYVFADLSDEGRAYFLTRQEPITKLTIFTE-HRSHIRRKGVASTLKNIAF--------------ESG-VNILPYLLLPVAEF-TDEESA-AMLPDL--QLLPPDKERDSDKDIIATHLETLLLLTTTREGRELMRAVNVYPIIRECHEGCDRLVQVLMRD-ELAKAK Klula1 ELEELVSFLH-SDQPAVRQIALDNLVGFSTG--AN------------NYKAIEDLKVLAK-DKVIVQQSTTILANLCDDVTMTEFLQYLSDLANASADIMC-ILLSNLAKDNI--TELFSFV-----FKSN---KVMDCLMDCFVKGKLNR------YATYDYLAYFFADISKIGREYFIEQQEPISKLLVFTEKYDAKTRREGVAYTIKNSLF--------------NEE-INLLPYILLPIAEI-DEEDMF-NLPDEL--QLLPADKERDPIPEIICVHLESILLLCTTKAGREYLRSKSVYPLVRELHELSHRIVNMLMRG-EAKSAE Lacbi2 QLRELIAFLR-DRNPQVRQIALSNLLPQTLKGSPGVS-AGGLQKAK-ESDIIRDIKLLCR-D-NVAHDAFRALINLSDSPLLPSFLSFIVEPQSILADLAS-MLLSNLTASGA-CSVLLTLKISVIPCGSCPAPMALPLLLDAFVDGGESE--DLSRKGELHFLASVFANMSPTGRNFFLSPQPALAKLVPFTE-HKNTIRRGGVASTIKNCSFPESALVSVPPSKLQSRG-IDALPYLLLPLAEF-ELDDQE-KLLEPL--QFLPPTKTRESDPTIRLTHVETLLLLCHTRWGRDYLRQHGVYEIVRAAHEHIERLVQLIHGD-EELD-- Lenti61 HFQELFQFLR-DKNPQVRQIALANLLGQTPKGSPGLK-GGGLQQKQ-ENDIIRDIKILCR-D-ATAHDAFRALINLSDNSLLVSFMKFLVNFQSILADLAS-MLLSNVTASSA-CSVLLNLKIPVLPSGTCPAPHALPLLVDAFVKAADDK--DLDFKGDLHFLASVFANISPAGRSFFLTPRSPLSKLLAFTE-HKDTIRRGGVASVIKNCAFEENETVTVPPSSVAAPG-IDILPYVLLPLAEF-DLEDQD-KLPSAL--QFLPPTKTREPDPVIRLTHVETLLLLCTTHWGRQYLRSHGVYEVVRALHEHVERLVNLLKRD-EHLGA- Malgl1 ASHELLVFLA-DANPQVRQLAMSSIVSFSGKNNPPLKDAHGTPKGE-PLDVIEQLKKLCN-D-LTVHDALSALINLCDTASVEEFLAFLVDSVSLLADLAC-MLLSNLTKESI-ASRLLTMEVEDRPANSM---PALVKLLRAFEEGETSRSSDADRKSTCNFLASVFANVTPRGREFFVAPM-PVGRMMVYTE-HADLIRRGGVISALKNIFFP-------TPAAAPVDS-LDVLPYLLMPLIKV-DIEDQE-SLPEAC--QLVDENKPREKDSALRLMLVECLLLLCTSHYGRESLRQRGAYIVVREAHEAIVRLVNLLKRD-EQLPAQ Mellp23 QLEELVGFLH-DRNPEVRRLAVNALLPYTPASNPS---KDSRKAGQLDQNIINDLKNLCE-D-LTAHDALSALINLTDADVVTDFLIFLLDPSAILADLAC-MLWSNLTKNSV---CVSCLKLPLVGEESIQKKPMMDLTIELFARGKINK------HANYDFLASVWANFSPDGRSYLLGISPPLAQISPFTE-HPSIIRRGGSISAIKNCCFE-------KPDG------LEILASILLPLCPF-DADDEE-HMPAEI--QMLGSDKKSETDLALRHILIETLILLSTSAGIRQYLRDKRVYRVVQVLHEQIERLVNILMRD-ETAECE Mnele -MDELPGLLHSRQPNKVRQGAAELILGLTSDAAS-------------NDELVHMIWETLD-DKKLSVAASQILVNMTS----PQILWILHTDAIHMYNSMA-MVLNNISRAKI-IVEMLSLK------------QLFLKLISC--------------NQEQGYLAAVLGNIADEGRKLLLQ---LFSELISLLTMPGNIIVRRNIARLLRNLSF--------------------FLPQIVYPLVEV-EDEDME-KLPLDL--QYLPEDKCRESDLQTRILLSDTLFQIGGSFSVREKFREENYYVLLKNYDERIQNVIYLIQEDGEELPQ- Monbr EVSELLGFMSLDTRLDVRSAAVDLVLGLTVSQDK-------------NREFVPALCTIVKEDVVIVKDAVAALINLAHDEDLEATTKHILDPEETYPDPFC-LLLVNLTRNEA-AERLCHHTVDEKP--------VVHELVRVFCLA-FNEN-----G-NLDHLANVLFNITSEGRRLVMARTNVIQRLLPFTQYVDSRIRRGGVIGALRNCCF--------------PE--VDLLPYLLLPLAEF-DDEDMD-GMPDDL--QYLPPDKKRDMDADIRMMLLEALLQLAATRGMREQMRRNKVYPILREYHDACEQVVQLLINE-ENVDPT Morel2 QIVELLPFLH-DGRMEVRQIAIHNIVSFTTPSSEN------------AKSLTKDLKTLVR-D-TIAHDALRSLINLSGEAVVNDFIKFLISKTNILSDLGC-MLLSNMCKDSI-ATKVLALE-----TNGT---TAVAQLADIFLKGSYNP------NCTYDFLASVFATLAPQGRSLLFTKDEPLSKIVCFTE-HPNLIRRGGCITTIKNASF--------------ESD-INVLPYILLPLCEF-DIDDME-GMPEDI--QLLPPTKTREADAHLRETLLEGLILLTSTREGRDYLREKKTYPVIQKMHEMAERIVNMLMRD-EEVKE- Mucci2 QIKELIPFLH-QPALEIRAIALHHLVPYTPNGNEQ------------KAGVCKDLKALVK-E-VTAHDALRALINLSSDPLVLDFINYIGNAKSVLADLAC-MLLSNMTKEPT-CVKVINSK-----IEST---RLLDQLVEVFHKGEYNP------EAEFHFLASVFSNVSRLGRVFMIEPAPPLTKIQIFTE-DRNVIRRGGVDSVIKNCCF--------------PND-INVLPFILLPLCEY-DIEEFE-QFPEEI--QMLDDDKKRENDRMLREMLLESIILLGSTRYGRDYLRQKQVYRVIQRLHEHCVTIVDLLIRD-EEIK-- Mydma AMKEILQFIDTLSPADYKNNILEYILGMTGTAEG-------------NDLLIKALKKLILYDEKARLNSLKIVVNITSMTKEPLFIKVMLEPESECSDLVA-MLLTNITQKNN-AEVVLDCILNNDN-------FSLNKFIDAFCNE-YNKK-----GCSLHYIGSFLANLTKETRHLFLKKDELLKRLLPFTEYEKSLSRRLSVSRIIKNCLF--------------DD--IDIIIHLLMPLAEF-TPDENE-CLPLDL--QYLPDTKQREKNKDVQILLCESLFQLCATKSCRLQLKNNGTYYVLREFHEPLVNLIQVLIGD-EEIPEH Neucr2 ELEELVGFIA-SPNANIRLLATENLVPFSAS---D------------ELTPIKHLKFLIR-D-KIAEHALTCLINLTAEKDVDRFLGILLEPEEVNANLMA-MLLANLTKDGL--KSLLDRK-----KSDD---RVINQLMDLFVKGTYNK------HADYDYLSYVFADLSEEIRHYFVNRQDPINKIKVFTE-HKSDIRRKGVASIIKNAAF--------------EDD-VNILPYILLPIMVY-PEDEAL-EMLTDL--QLLPPDKQRDPDSSNILTHLETLTLLTTTRAGRDLMRSISVYPIVRETHDACERLVNVLMRD-EEGGAA Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQGRKHFLRNVELLGNIICFTE-HPSLLRRGGVISTIKNCCF--------------PDG-LNLLPRILLPLADF-NDEEME-ALPDEL--QLLEPTKKRESDSYMRELLIESLILLATTKYGREYLRSHSVYPIIRE---------------------- Pench1 ELEELVEFLH-HGNTQIRQIACENLVGFSTA---H------------QLLPVRDLKLLAR-D-PIAKNALTMLVNLSGDEEVDKFIETLLNPKEPNADEVA-MLLANLVKETL--HKLLSLK-----STSE---NAIDQLMDCFVKGALNK------HANYDYLSYVFADLSEKGRAYFTQRQEPITKLTVFTE-HRSDIRRKGVASTIKNVAF--------------EDG-VNLLPYLLLPLAEL-SEEDTA-DMLPDL--QLLPPDKQRDSDTSIITTHLETLLLLTTTRDGRDKMRAVKVYPLIRETHEACDRLVQVLMRD-EQIEAP Phybl2 -----MDFLH-QPSMEVRSIALEHILSFTPKTSQN------------RKTLCTDLKNLCR-Q-MIAHEAMKGLINLSGDPRIEAFLKHITISKSVLADPAC-MLLSNMTKESI-CVKLLEMK-----CESD---KVMDQLVEAFHRGAYNP------QAEYHFLASVFSNVSRLGRVYFLEPSKPLTKLQIFTE-DKNIIRRGGVDSTVKNVCF--------------ADK-LNTLPFILLPLCEY-DMEEFE-QFPEEI--QLLDDDKTRESDKVLRGILCDALLLLTTTRFGRDYLRNKQVYRVIQRLHDKCDAIADMLIRD-EPIDE- Picst3 ELEELVSFLH-SPQPAVVSIALDNLVGYSQG--PD------------NYEAIKDLKKLSQ-EKTHVVQSVTILANLCDDLTMEAYLKYLVNVNNSNADIMC-ILLTNLAKDSI--NKVLDFT-----FKSN---KAMDCLMDCFVKGSLNK------YADYDYLSYFFADISSQGRAYFITEQEPLSKLLVFTEKYDSRIRREGVASTIKNSLF--------------EEK-INILPYILLPIAEI-DEDEMF-DLPDEL--QLLPSDKKRDPLNTIICVHLESLLLLCTTRQLREYLREKSVYTLIRELHDLCDRLVQMLQRD-ES---- Plicr1 QLKELFPFLR-DKNPQVRQIALANLLAQTPKDAPGLQ-AGGLKKPQ-EPEIIRDLKLLCR-D-AVAHDAFRALVNLSDSPLLPSFLAYVVNPQSILADLAA-MLLSNTTATAA-CSALVSLNVSIV-SGTCAAPLALPLLLDAFVQGSLKE--DKARKGELHFLASVFANISPAGRNFFLTPRPPLAKLASFTE-HKDTIRRGGVTSTYKHCAFPETDMVAVPPSTVTAPG-INVLSDILLPLAEF-DLEDQE-NLPPAL--QFLPPDKKREPDVVLRDTHVETLLLFCVTRWGREFLRNNGVYEIIRAAHEHIERLANLLKRD-EHEDQA Polpo QLTELVPFLQ-EQKPEIKILALQHIAGVSGE-QP-------------KTNIINLLIRLIG-DQTINRLTLTTLINFCQDNDMRNIVPRLVDTKNKLREIYS-ILLSNITHKEG-CISLMQYG------------FYILKLSNLLTVS------DEDVSKKGAWVVNILLNITEEGRNIILNQE-IFKSLLPLIQ-HQSVVIRRGIVGIIRNCCF--------------ES--IDVLTKILLLIRIL-TDEEME-GMNQLLHNKPEQASIEREQDKETRKMVIESLIFLTGTKESRAILRDKKTYPIIRNYHENIEKIVEMLIRDEEEMD-- Pucgr2 EMGELIEFLH-DRNPEVRRLAVHGLLPYTAANHPN---SSGLKPGSIKPGIIEDLKRLSE-D-MTAHDAFSALINLSDTAPVPDFLSVIFDHDSLLADLAC-MLLSNLTKDSIVNLCLSSTIPPHTSDESLSARPLMDLLIELFARGQINP------HANFDFLASVWANLSPKGRDYLVGVSHPLFQLSPFTE-HPSLIRRGGVISAIKNCCF---------PTG------FNLLPAILLPLMALDDPEEQD-EFPVEC--QLLGPDKRRETDPNLRLILVESLILLATYPFQREIMRKKKVYRIVQILHESIERLVNLLMRD-ETKQIH Punst1 QLKELLPFLH-DRNPQVRQIALSNLLGQSAKDAPGVS-SGGLKKGQ-DTDVIRDLKLLCR-D-ATAHDAFRALVNLSDSALLHDFLAFIVHPQATLADLAS-MLLSNLTAGPV-CATLLSLKIPIIPCGSCAAPLALPLLIDAFVAAATKSADDSNRKADLHFLASVFANISPAGRTFFLTPIRPLSKLVAFTE-HTDIIRRGGTASLIKNCAFEQTTLVTVPPSTVEAPG-VDALAYILLPLAEL-DLDEQE-LLPEAL--QFLPESKKREPDPAIRLIHVETLLLLCTTRYGRDKLRSTGTYQIVRLLHEHVERLVRLLKGD-E----- Rhior3 QIKELIPFLH-QPALEIRAIALHHLVPYTPNGNQQ------------KQTICKDIKALCR-E-VTAHDALRCLINLSSDPAVQDFIKYICNAKSVLADLAC-MLLSNMTKESA-CVKLIQAK-----SKST---RMLDHLVEAFHKGDYNP------EAEYHFLASVFSNISRLGRVYMIESSEPLTKLQIFTE-DPSIIRRGGVITVLKNCCF--------------VDQ-INALPFILLPLCEY-DMDEFE-QFPEEI--QLLDDNKV------------------------------------------------------------- Rhoto1 QLLELFQFLA-DAQAPVRRIALATLLPYTAPDAP------------LRDSHVEQIATMCA-D-LIAHDAISALINLSSMLEVPGFVTGLVDEKALLSDLAC-MLLSNMSKDSV-SRQILGLRVPVGSGEAAGGTAALDLLLEVFLRGKYNP------NANYDFLASVFANVSPQGRAFLLATPDPLAKIISFTE-HPSTIRRGGVASTIKNAAFP-------SNDGPAEEGCIDLLVQLLLPLCEF-DIDVLD-ELPAEL--QLLPSDKTRESDPQIRTILVETLVLLATNRSNREAMRKRGVYPVIKEAHEAMVRLVNLLMRD-EEAPAE Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 QLNELVEFLH-SPQPAVRQIAIDNLVGFSAG--PD------------SYRPIKDIIKMIM-DRVIIQQGVTILVNLSEDKLVKKFLKFLVDLTNPNADIMC-ILLSNLAKDGI--LAVLNIK-----FKSL---RAMDCLMDCFVKGKLTK------YASFNYLAFFFADISKLGRMYFIEEQEPISKLLVFTEKYDAKVRREGVASTIKNSLF--------------DEK-INLLPYILLPIAEI-DEEDMF-NLPDEL--QLLPEDKERDPIPAIICCHLESILLLCTTHAGREYLRDKSVYPLVRELHELCYRIVNMLMRG-ESKNAE Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 QLNELLGFLR-DRNPSVRQIALSHLLPHTPQGAP-------------TPAAIQNLKLLCR-D-AVAHDAFRALVNLSDDAKAPSFLAFLAARQATLADLSA-MLLSNLTAAAA-CAAMTTLEIPVLPCGSCPAPRALALLLDAFVQGSGTD--DLDRKSALHFLANVFANLSAAGRRFFLTPTPPLAKLTPFTE-HADRIRRAGVASTIKNCAFPETEQVPAPPSTVTAPG-IDVLVPLLLPLAEI-DLEDME-KLPIAL--QMLPETKKREPDATIRHTIAETLLLLCSTRWSREKLRNSGVYEVIRAAHETIERLVNMLKRP-EELDSK Schpo1 ELIELVGFLH-DQNPQVRMLAVQHLLPYTARNHPN------------DFEPVKDLKALLK-D-QIASQAVTALVNVSQNEKVDEFLQLIFNPLHGLADLSC-MLLCNLAKEDF--ARILDMQVP-----SK---NIIDQLMDLFVKGGINE------YANFDFLANVFADMTERGRKYFTTLQEPASKLVVFTE-HKSLLRRTGVAAIIKNISF--------------EEG-INVLPYLLLPLAEL-SEEDMD-GMFDEL--QLLPDDKKREPDHFIMKTLVETLVLLTATREGREHMRRRKVYPIIRELHEVCDQLVQMLVRD-E----- Sorma ELEELVGFIA-SPNAKIRLLATENLVPFSAS---D------------DLTPVKHLKFLIR-D-KIAEHALTCLINLTAEKDVDRFLGILLDPDEVNANLMA-MLLANLTKDGL--KSLLDRK-----GSDD---RVINQLMDLFVKGTYNK------HADYDYLSYVFADLSDEIRHYFVNRQDPINKIKVFTE-HKSDIRRKGVASIIKNAAF--------------EDD-VNILPYVLLPIMVY-PEDEAL-EMLTDL--QLLPPDKQRDPDSSNILTHLETLTLLTTTRAGRDLMRSVSVYPIVRETHEACERLVNVLMRD-ERGRA- Sphar GTQEYMTFFR-------------------------------------SNQTLKGFFAIVNMDEQNRKMALSAIVNLSADAIVKNIVSMLIDPESEFADLSC-NIISNLTRNEA-CHIILSSTVG---QETGTAPPAIYKLLDTF---GYNKK-----NQKLHWLGAVFANISPEGRAIVINKE-AFQRLLTFLN-HTEPVRRGGVVAMIRNVAF--------------DD--VNILPALLLPLAEF-DEEEME-GMPDDL--QYLDDDKTREPDIALRKMLVETLLQLCTTRSGRDTLREKKVYPIIRELHKSIYDLVQILQGD-EAIPED Spipu1 QLDELFSFLR-DPRPDVRQLAAKNIAGLT-TTPED------------GCRVVKDLMALTK-G-LAAHDALSALINLCVDPVFEDFLYDLILPRNVVADLCC-MLLNNLSENSV-ARKLVADI-----SPSAESTHYLDNLLEVFVRGGYNP------DAEYHFLGGVLSNVAPAGAAWFRGRTGRLSKMVPFTE-HPNRIRRSAAIHTIKNTAF--------------DTE-LNLLPYLLLPLSDY-TDEEME-GMPDEL--QLLEPDKEREQDAKLRLALVEILLLLTTTRQGREILRAKKVYPVVQKLHEAIERLVQMLCRD-ESVDAK Sporo1 -----------------------------------------------------------------------------------------------------------MSKDAV-SLQILNLRVPFSVSTSAGTSLALDLLLEVHLKGKYNP------NANYDFLASVFANISPQGRAFLLAAPDPLSKLISFTE-HPSPIRRGGVASTIKNAAFA-------KNDAPAEEGCIDLLVQILLPLCEF-DLDIMD-ELPQEL--QLLPPEKEREPDATIRAILIEALVLLATSRANREAMRTRGVYQVIKVAHEPMIRLVNLLMRD-ESKPIE Stehi1 QLRELLPFLH-DPNPQARQLALENLLAQTPKGSPGMQ-GGGLKKPK-DSEVIRDLKLLCR-D-AVAHDAFRALVNLSDSPLLPTFLNFLVNPQATLADLAA-MLLSNLTTSST-AAALLSMKVKVIPSGSCAAPPALPLLLDAFVRGDPDN--EEGQKSSLHFLASVFANVSPVGRQFLWTPQHPLSKIVAFTE-HKDTIRRGGVASTIKNCSFPETDLVIVPPSTIKAPG-VDALPFILLPLAEF-DLEDQE-LLPAAL--QFLPPTKQREADPTLRLTHVETLLLLCTTRWGRDFLRNHGVYEIVRALHEHIERLVNLLKGD-EEVDQG Tapde11 KIL---------KSGQLR-----QLVPYSTRGNPD------------QFRPITDLRILIL-D-KTAHDSITILINLSQDPLIEIFLNMLLNKENGLADLAC-MLLSNLAKESI--KRLLTMT------ESD---GVMNQLLDVYVRGQLNP------HANYDFLTNLFSDLTPEGRTYFLTTQPPLSKLVVFTE-VTSQIRRTGVASVIKNCCF--------------EQG-LNLLVYLQSPLCGF-SDEERD-GMFEEL--QFLDDAKARESDEFTVTIILDALLLLCSTRSGREHLRQRQTYPIIRQLHECCDKLVNMLMRD-E----- Thetr ALLELVDFLN-DPKAEVRAIAADHLAPYCDVPEA-------------RKVLLERLGAMMG-D-PIAHNAMRALINLSAETGTPRLLEVLLDPDAVISELAA-MLLANCTREAA-VHDLFDVW------------IAIVKLVRAF-----------------------FHNPTTFSPRLFLKK--LLAQLLPFLD-DESVIRRGGILGTVRNLVYP---------------GPINLLPKLLKPLMRVLEEDDVV-GMPLEI--RQLPYTHQRESDPELRRMIVDTLFYLSLEADSRQILLDSKVYVVVRNAHQAMFKLIDVLVKD-DAADPE Treme1 DLVDLFQFLD-SPNPSARHLALQNLVGHTAKSDPSID-SDG------KIKAIKDLTSLCR-D-FIAHDALSALINLSDTLAAQEFLVWLVNTTSTLSPLTS-MLLSNLTSPTL-LPIIASLQIPISRISSTIHPEAVRALAEAFADGDVKK-----RKGECHFLASVFANISPTTRSLLLVPRPLLAKIVVYTE-HSDTIRRGGALGCIKNCAMSENDRVKL------SDG-VDVLPWVLSPLMEY-DMEEME-QLPLSL--QFLPDTKVREKDIVLRMMCVEILLLLATTFTGRQSLRSRGAYFVVREAHEAIERLVSLLQGE-E----- Trire2 ELEELVGFIA-HPNPQIRAVAIENLVPFSET---E------------QLKPVKHLKFLVR-D-KIAEHALTILINLTGDQEIEKFLEMVFHPEEPNADLLA-MLLANLSKSHT--KSILHRT-----SSSD---RVIDHLMDLFVKGAYNK------KADFDYLAYVFADLAADVRQYFLAEQPPLTKLKVFTE-HKSDIRRKGVANTIKNAAF--------------DSG-IDILPYVLLPITEY-DDDDSM-DMLPDL--QLLPPDKKRDSDTSNIQTHVETLTLLTTTREGRDLMRKVKVYPIIRETHEACDRLVQVLMRD-EEA--- Umbra1 QIVELIDFLH-EPKLEVRAIALHHLTGFTHQNSGK------------RQTVIPDLKALCR-E-ITAHDALKSLINLSGDPRTDKFIKHICIPKSILADVAC-MLLSNMTKEPI-CVKLIDAK-----SEST---RLMDQLVEAFHKGNYNP------QAEFHFLASVFANASRHGRVYFVEKASPVTKVQIFSE-DKSVIRRGGAISTMKNCCF--------------VEG-TNMLPFILLPLCEY-DMDEFE-KFPEEI--QLLDDDKTREADPLLRLMLCESILLLTTTRNGRDYLREKQVYRVIQRLHDKCQDIVDMLMRD-EEINEH Ustma22 PELEVLTFLS-DPNAQVRQVALSNIVGFSAKDSPKHKNRDGGRDGK-EVDTVEDLKRLCQ-D-ITAHDAFSALINISDSLVLKGFLEFLVDPVSLLADLAC-MLLSNLTKESI-CAILLDLQVQARPEQAK---PAMARLLDAFEEG-ASQGSDLERKTNCNFLASVFANVTPRGRDWFVTPLSPVARIMAFTE-HPNLIRRGGVISTLKNVLFP-------PPARDGEDS-VDILPYLLLPLCEV-DLEDQE-ELPEEC--QMLPEDKKREKDPALRLMLVESLLLLCTNIYGRQCLRARGAYVVVRSAHEAVLRLVNILKRD-EDVGAE Walse1 EFKELVTFLR-NENPTIRQIAIQNLAGFSTT----------------DNQSIQEVKLSCR-D-AIAHDAFSILVNISDSVLTNDFMVFLTNPTALLADLAC-MLLSNLSKPNV-IHTICSQQIP---SSTV---RAVPCLVEAFVQGPETAVESAERKSNCHFLGSVFANITQPGREYFTSPSPPLAKLTAFTE-HPNNIRRHGVASTIKNSTF--------------EDG-VNMLPYVLLPLCEF-DIDEQE-ALPEVC--QLLPETKKREIDPSVRKTHIETLLLLCTTLHGREYLRSRNTYVVIKAAHDEMIKLVNLIMRQ-EELSAK Zygro1 QLEELVSFLH-SPQPAVKQIALDNLVGFSQG--PD------------NCRAIEDLKDLAK-EKILVQQSVTILANLCDDDLLVNFLEYLSDFGNTSADIMC-ILLSNLAKNTI--NKIFTFT-----FKSN---RVIDCLMDCFVKGKLNK------YSTFDYLSYFFADISKAGRQYFIDTQEPISKLLVFTEKYDSKIRREGVASTIKNSLF--------------DES-INLLPYILLPIAEI-DEEDMF-NLPEEL--QLLPEDKTRDPIPSIICVHLESILLLCTTKTGREFLRSKSVYPLVRELHELCYRIVNVLMRG-EARSAE [Cluster2195.fasta_al_trimmed; alignment length = 106] Allma1 KQETRTAGDKWFNLPATETPELQRDLFLIKNRHVLD-PKRHMPKFFQVGRIVEGKHEFYSSRL-TRKERKN--TLVEELLADTERRTYKNQAKSIVMNKAKKMQKK Ashgo11 RARSAPPAADWFQLPRPETPELRRDLALIKHRAALD-PKRHVPERFSVGTVIEGTGEFYSSRL-QNSQRKA--TMLETLLADDDSARYRRRYAEVQVTKTSRDRRR Aspfu1 NSSTQTAGADWFHLPKTETTELKRDLQLIRMRSVLD-PKRHPPKYSQLGTIIEGPTEFFSGRI-AKKDRKK--TFVEDVLALERETKRASKYREIQISKQSRAKRN Aurde31 KRDKKTAGPGWFDLPAPSLPRLHREVDAMRLRNQLD-PKRFLPKYFAIGKIVSTPSPF--DNL-PRAERKR--MVVDELVDDAEARRYKRKFGEFNAGREAKAARQ Batde5 -----TAGPGWFDMVSAETDEVKRDLHILRSRAALD-PKRHFPKVFQFGTIIEGPTEFYSSRL-TNKERKQ--TIVDELLSDAKTKAYKRRTAEVHEKKNNKQRKN Botbo1 NREKKTAGPSWFDLPAPALPRLYREVEALRLRNQLD-PKRFLPKYFAVGKIVDTPTPF--SNL-TCAERKR--TIVEELVDDAEARSYKRKYEDLQRVRGEMEGRK Botci1 KAKVATAGAKWYNMPKTVTPELKRDLQLLRLRSVLD-PKRFVPEYSQVGTVIEGPTEFFSSRL-TNKERKQ--TFVEQVLAGEKANHKRNKYNDIQAAKASKALRK Caeel ARLKKTKGSAWFNLPATETDEHKRDLEFLQMRSTLD-PLAHLPKYFQVGRVVDAPEDFYSSRM-VRKERKK--TMVDEILHNEESLSKKKKYAEIRQKEQSKQQRE Canalb1 PKKKT-SDERWFNMKQPETPEIKRDLQIIKQRSALD-PKRHIPKFFQMGTIIEGNTEFYSSRL-KRKERGK--TMVEELLHDDTTKKYKRKYHEIQQTKTSKNARK Cangl EERRKKTSEEWFTLPKPDKREIQRDLLLIKHRAALD-PKRHVPDRFSVGTIVEDKTEFYSSRL-TNKQRKS--TMLETLMTDDTTNKYKRKYSQIQEQKMSKAARH Capow TGRKK----KWGDLPVGNTPEVERDLRLLRMRNYLD-PKKHLPKHFQIARVVEGPTEFYSSRL-TRKERKN--TLVDELMADDRLRKYKRKFVEIEQRNAQQQKRK Catan2 -------------MPAGDTPEIKNDLFIIKHRDILD-TKRHLPKFFQVGRVVEGKHEFYSSRM-TKKERKN--TLVEELLKDTERRRYKRKAEEISEKKAKKAKRK Cioin ASRRSTSGKKWFNMKCPETEEIRNDLKVLEMRSVLD-PKRFTPKFFQMGKIMDNSADFYSSRV-T----------------------------------------- CocheC53 KKQKQTAGSQWFNMPKTDTPELRRDLQLLKMRSVLD-PKRHVPAFSQVGTIIEGATEFYSSRL-KNKDRKQ--TMLEEVIAQEQDSGRNRKYQDIQATKSSKAKRN Coere1 AGEALTAGKNWFGIKAPTTPEIKNDLRVLQLRNVLD-PKRFLPKYFEIGTIIEGPTEFYSSRL-TKKQRQN--NLVDELLADKQSRDYKRKVGEIHARNYSTGGNA Conco1 RQEAKSAGPKWFNMPTATTEEAKRDLHIIKLRNVLD-RKRFLPKFFQFGTVIEHSSEFYSSRI-NKKDRKS--TLVEEVLSDDKSKEYKRKFNEIQEVKSSKGKGK Conpu1 KKERKTAGAGWFDLPAPALPRLYREVEALRLRNQLD-PKRFLPKHFAIGTIMPTDSPF--DNL-ARAQRKR--TFVDELLDDAESKHYKKKFQELQTVRGANAKRK Copci KKEKKTAGPDWFDLPAPALPRLYREVEALRLRNQLD-PKRFLPKYFAMGKVITSDSPF--ENL-TRADRKR--TLVDELVDDAEARRYKKKFNDLQGVREAQNARR Croqu1 -------KVGWHELPQQE-PEVKREIQAMRLHGTLD-PKCFIPDRFQFGHII----PS--TGT-EAIPKKR--SFVEALIADEEAKGWKKKYVNEVQISGAQKKRK CryneH991 SSEKTTTSELWASIPTPRLPQMRKDYRALALANSLD-PKRFIPESFAIGTMVETSRQIRDTTL-TKDNRYRPGQVVQNIIRDQDMEGYKRKYGDLQWSKME----- Crypa2 KSKEKNAGAKWNYMPRTKDPKVKREFQLLRLRGVLD-PKKHFPQYSQMGTIIEGPTEYYSARV-NRKDRKQ--TLVEEVLASGEANSKKTRYAKIQEKKTSMARRK Debha1 KPKKADSGSKWFNMKQPETASVKRDLSIIKQRNALD-PKRHIPKFFQMGTVVEGNTEFYSARM-NRRDRGN--TLVEEVLNDNDRKKYRRKYTEIQDKKTSKSMRK Dekbr2 PKKGQKRTAEWFDLPKTETEDMKRELSIIKYRQYLD-PKRFIPERFQMGTIVGGPTDYY-NRL-TKKQRGE--GFIEEILNDPDAKAWHKTYEGIQKEKVSVAKRK Dicdi ---------------------------------------------------------------------------------------------------------- Dmel VGKRQTKGKGWFNLPATETDEMRNELKIVQMRSVLN-PKQFLPKFFQIGTVLPSHLDHYQEKK-SKK--KQ--SLVNELLEDESFQKFKRKFNEVIKRTDKKKLKK Enthi ---------------------------------------------------------------------------------------------------------- Falba -------------MRSPETPEMRRDLQVIRMRAYLD-PKLHLPKHFQMGTVIGGATGYYR-RL-TRRQRAT--SLVDSVLGDTRTASYRSRFTQAQQHKSQQHKRF Fomme1 KKELKNAAPGWSDLPTPDLPRLYREVEALRLRNALD-PKRFLPERFAIGTIVTTKTPF--ENL-ARSERKR--TLVDELVADSEAKRYKRKFGDLQTVRAAAAARR Fusgr1 SGLKVTAGADWFDLPKTNTPEFKREWQVLRMRGILD-PK-HAPEYSQVGEIIEGPTEFFSARL-TRKERKQ--NLLDEVTRGIDTHK-TDKYAGIQKQKSSVATRR Galma1 KKQKKTAGPDWFDLPAPSLPRLYREVEALRLRNQLD-PKRFLPKYFAVGTILPSTTPF--DNL-TRANRKR--TLVDELVDDAEAKRYKKKFEDLQSVRGAQALRK Ganpr1 GDDKKTTGSKWFDMKTPATPELKRDLQLLKLRGVLD-PKQFLPKHFQVATIVDSPHEFFSARL-SARERKQ--TLVEEVMADVDRRKWKKRYNEVQTKATSTEKRK Gloin1 -----TAGPGWFDMKKPETPEIKRDLQIIKLRNVLD-PKRFLPKYFEIGTIKEGPAEFYSSRI-PRKERRQ--TIADELLTNEQSKRYKRKFSEIQEIKQSKAKRR Hisca1 KIKMPTAGSDWFDLPKTNTPEMKRDLQLLRMRPVLD-PHRHAPEYSQVGTIIEGPTEFFSARI-PKKLRKR--TFVEEALAIEHESGRRRKYEEIQAAKTSKAKRS Klula1 ESRKKTETEKWFTLPKTETAEVKRDLMIIKHRAALD-PKRHIPERFSVGTIIEGPTEFYSSRL-KNKERKN--TMLETLMADDTTNKYKRKYTEVQQKKTSKDKRR Lacbi2 KKQKKTAGPDWFDLPAPSLPRLHREVEALRLRNQLD-PKRFLPKYFAIGTILPSSTPF--DNL-TRANRKR--TLVDELVDDAEAKRYKKKFEELQSVRGARAVRR Lenti61 KKELKTAGKAWFDLPAPPLPRMYREVEALRLHKQLD-PKQFLPKHFAIGTIIPSNSPF--DSL-PRSARKR--TLVDELVDDAEARSYKKKFKELQTVRGAKALRK Malgl1 KREIRDAGPKWFGMPGFPEKEMRRQVTAIRLRNALD-PKRFMPAYAQLGKIVGGGLEP-SSML-TRKQRSD--SVVGELIRDSASVSYKRKFGEACGV-------- Mellp23 --------MSWHDLPYQE-PEVKREIQAMRLHGTLD-PKRFIPDRFQFGHII----PS--TAK-ESIPKKR--SFVEALIEDEEAKKWKKKFLNDVQAKGAKQKRQ Mnele KKERKTLGKNYFDFKPSETEELKRDLKIIKSRNLIG-KGAFLPSAVQIGTIVEDKSEFYSSRV-PKKMRQK--TLVDELAADFNFRKKKDKFMKIQSSKPKKKKRK Monbr EAIRRTAGRKWFNMPATETPEVAADLKILGMRDVLD-RKRHPPKFFQVGRIVDGAADFYSDRS-TKKAAKR--TLVDELLEDQSTRRYKQKFVQLSQSKFAKKQLK Morel2 KRQKQTTGKKWFDMPQQVTPELRRDLQILRLRNVLD-PKRFFPKYFQVGTIIEGNTEFYSSRL-SKKERAT--TITGEVMKDVAGRDYKRKFDEIQVAKQSKGKQS Mucci2 -----TTGSAWFDMPKTETDEVKRDLQVLKMRHILD-RKRHDPKYFQIGTIIESPTEFFSARI-NKKDRKQ--TIVDELMASDELKQYKRKHTEVQERTNSKAQRQ Mydma KNSKQTAGKGWYNLPKTETEEIKRDLQIIKMRGVLD-GKHHLPKYFQIGTIVEGAHEFYNSRV-PNKKRKA--TIVDELLNDAEFRRKKKNFLQLQKKKMSINKSK Neucr2 SKDKSDAGADWFNMPRTNTPELKRDLQILRMREVVAMGKQYVPEFSQVGTIIAGATDGRDSRL-TRKERKR--TIVEEVLGAEVVDKYKNKYHGIQEKKQSVNGRR Orpsp11 ---------------------------------------------------------------------------------------------------------- Pench1 K-KVNTAGPEWFNLPKTETTEFKRDLQLIRMRSVLD-PKRHPPEYSQVGTVIEGPTEFFSNRI-TKKDRKK--NFVEETLALERGTKRQSKYRDIQASKTSQAKRT Phybl2 KKERQSTGKGWFDMERPETDEIKRDLQIIKMRHVLD-RKRHNPKFFQVGTIIESPTEFFSSRI-AKKDRKQ--TLVDELLADEQSKQYKRKFDETQERTTNKQKRK Picst3 K-QKVDSGSKWFNMKLPETALVKRDLQVIQQRSALD-PKRHIPKYFQMGTIIEGNTEFYSARL-SRKQRGT--TLVDEILHDDDTKKYKRKYSEIQDKKTSKEMRK Plicr1 KKEKKTAGKDWFDLPAPALPRLYREVEALRLRNQLD-PKRFLPKFFAIGTVVPSSTPF--DNL-TRAARKR--TLVDELVDDAEAKRYKRKFEELQSVRGAMALRK Polpo ---------------------------------------------------------------------------------------------------------- Pucgr2 KLKEHLAKLQWHDLPTQP-RETKLEIQAMRLHRTLD-PKKFIPEKFLFGHLV-----ETPTHH-SSSTKKR--SFVDSLVSDQHGLGWKNQY------EGLNRSKK Punst1 KKERKTAGASWFDLPAPPLPRLYREVEALRLRNHLD-PKRFLPKYFAIGTVVAERSPF--SNL-TRAARKR--TLVDELVDDAEAKSYKKKFKELQTVRGANALRK Rhior3 RKERQTTGKDWFDMPRPETPELKRDLQILKMRHVLD-RKRHDPKYFQVGTIIQGPTEFFSARM-TNKERKQ--TIVDELLASDEQKQYKRKHNEVSTRSNRKAQRK Rhoto1 KKQFKTAGKQWFDLPATP-PELKRELDALRLSNSLD-PKKFVGEFFQIGHVI---APS--LST-PAIPQKR--SFVEDLMADEESRAYKRKTKEVMS-KTMGNGRE Rozal11 KSQISKSTEKWASFTPSATEQLQKDLTFLGMRSAID-TKHF----VQVGKVIPGALDFIRERLYEKKSKGE--TWVEELMKDKEKRKTKERMKKVQTVHAGQMKKN Sacce1 EDKRKKNDNDWFTLPKPDRREVQRDLLLIKHRAALD-PKRHVPERFAIGTIIEDKSEFYSSRM-NRKERKS--TILETLMGDEASNKYKRKYNEIQEKSTSKEMRK Salro ---------------------------------------------------------------------------------------------------------- Schco3 KREKKTAGPAWFDLPAPPLPRLYREVEALRLRNQLD-PKRFLPKHFAIGTIVPSPLPF--ENL-TRAERKR--SLVDELVDDAEATRYKRKFGDLQGKRGAQ--RR Schpo1 GISKKTAGSNWFDMPATETESVKRDIQLLKMRNALD-PKRHMPKYFQVGSIVEGPQDFYSSRI-PTRERKE--TIVDELLHDSERRSYKKKYLELQKSKMSQQRRK Sorma SKERPDAGADWFNMPRTNTPQLKRDLQILRMREVVAMGKQYVPEFSQVGTIIAGATDGRDSRL-TRKERKR--TIVEEVLGAEVVDKYKNKYHGIQEKKQSVNGRR Sphar ------AGPGWFGLPATE--HLKAELQAIKMRGYID-PKRFMPKFFSVGTVV-----SGNDPT-TRPSVKG--GLVDELLADDKSKAYKRKFKEVQAKKLSQKKRA Spipu1 KKKKKTAGPKWFDMPAPDTEEIKRDLHILKSRAVID-PKRHLPKFFQIGTIVQGPTEFFSSRL-TRKERRD--NIVDELLADNQAKSYKRKFLEIQEQKNNKDRK- Sporo1 ----QTAGSKWFDMPATP-PELKREIDAMRLRNSLD-PKKFIGEFFQVGHVI---TPN--SNS-LPTASKR--SFVEELVEDEQARAYKKKTKEVMQ-KGM----- Stehi1 KKQQKTAGKGWFDLPAPRLPRLYREVEALRLRNQLD-PKRFLPKYFAMGKIVETNTPF--DNL-GRAERKR--SLVDELVDDAEAKRYKKKFGELQTVRGAKDKRK Tapde11 ADAQAQVGTDWFEIKTPETEDIKRDLQVLKMRSILD-PKRHLPKTFQMGTIISDSTESAAHKI-RRKDQKE--TIVEELLNDMTRRDYKRKAAEIDVKKRSKDRRG Thetr KEERRYASKDWFNMPAPETAEVKRQLDVVRLRAYTD-PKRFYPKHFQFGTVIESKKDFYSARI-AKKDRGK--DLVDELLKDEKVAAYRDKSAAGMVGRYERQKRQ Treme1 ---------------------------------------------------------------------------------------------------------- Trire2 AASQRTAGAEWFDLPKTDTPEFKREWQLLRMRNVLD-PK-HAPEFSHVGRVVASPFEPRSARL-GSREKKK--TLLESIMSVHNDAK-DSKYSSVQEKKREVAKRR Umbra1 RKDKQTAGKGWFDMPKTETPEIKRDLQVIRLRNVLD-RKRHDPTYFQVGTVIEGPTEFFSSRL-TKRERKQ--TIVDELLADDEARGYKRRFLDVQSRTQNKAKRA Ustma22 DKKKSSTGSSWFDMPEFGAEQLRREVQALRLRNALD-PKRFMPKFAQLGKIIASPLEP-KAVL-SRQERGR--TVVEELIRDAEAASYKRKFAESQASHRSKKKRT Walse1 RKQMKTTGKDWFDLPAPPLPEWKREAEALQLRNSLD-PKRFLPKHFAIGRILPGRNAGGAEDS-KARRQAR--GFVNELLDDKTSQRYKRKYSELQAERGQERKRR Zygro1 GKEKKPTNEEWFTLPTPTAHRVQRDLQLIKHRASLD-PKRHAPERFAVGTIIEDKSEYFSGRL-PRRQRGE--TMLSTLLKDVDSRSYKRKYGEIQTEK-RKGKR- [Cluster2197.fasta_al_trimmed; alignment length = 85] Allma1 DYQPDVCKDYKQTGFCGYGDSCIYLHDRGDYKQGWQLDADQLPFACFICRDPFPIVTKCGHYFCEACAMKRPTCAVCAKPTMGLF Ashgo11 DYQPDVCKDYRQTGFCGYGDSCKFLHSRDDFRAGWRLNEDSIPFRCVLCRGHYPVRTRCGHYFCGGCFARRRQCAVCGADTQGVA Aspfu1 DFAPDVCKDWKQTGFCGFGDSCKFLHAREDYKQGWELDRESIPFACIICKSSYPIVTKCGHYFCESCALQRPSCAACGAGTGGVF Aurde31 DYQPDVCKDYKETGYCGFGDSCKFLHDRGTYLSGWQIDKEDIPFACLICRKPYPVVTRCGHYFCSACAIKRPKCLACSAPTNGIF Batde5 DYQPDICKDYKDTGYCGYGDSCKFMHDRGDYKAGWQIDRSHLPFACLICRGPFPVVTKCSHYFCEACALKHAKCFACNAATGGVF Botbo1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLQGWQLDKEDVPWACYICRKPYPVVTRCSHYFCSACAIKRPKCAACGAPTGGIF Botci1 DFAPDVCKDYKTTGFCGFGDNCKYLHAREDYKAGWQLDKENIPFACILCREKYPIITKCGHYFCESCALKRPSCAACGAGTSGVF Caeel DFAPDICKDYKETGFCTFGDSCKFVHDRSDYKHGWEIDEDTFPEDCFICGNPFPIVTKCKHYFCTGCALKSSKCPICQQNTENIM Canalb1 DFQPDVCKDFQQTGYCGYGDTCKFLHVRDESRQKIPIKKEDIPFKCVLCKSDYPIKTECGHIFCKACFLDRGTCFICHKETNGTM Cangl DFQPDVCKDFKQTGYCGYGDSCKFLHSRDDFKAGWTLATEAVPFKCVLCKESYPVKTNCGHYFCQKCFVNRKSCFICGENTEGIA Capow DYQMDVCKDYKETGFCGFGDTCKFMHDRGDYKTGWQLDKDDLPFACHICRGDFPVVTRCKHYFCEKCALEHSLCAVCQSATNGMF Catan2 ---------YKQTGFCGYGDSCKFLHDRGDYKSGWQLDKDELPFACFICRGEFPVVTKCGHYFCEACVVERGKCAACGEQTGGIV Cioin DYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERDELPFKCFICRKSFPISTRCKHYFCEQCALNHRRCFVCGEQTNGVF CocheC53 DYTPDVCKDYKQTGFCGFGDNCKFLHAREDYAAGWKLDREKIPFACIICKKPYPIITKCGHYFCEACALKRPTCAACSAKTYGVF Coere1 DYQPNVCKDYKDTGYCGYGDSCIFLHDRGVYKTGWQLEKEQLPFACLICRKPFPVMTKCQHYFCEACALAHPKCFACGAATAGVF Conco1 DYQPDVCKDYKETGFCGYGDSCKFLHDRSDYKAGWQIEREELPFACFICREPYPVVTKCKHYFCEKCALNHAKCFVCNAATGGIF Conpu1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLAGWQLDKEDVPFACLVCRKPYPVVTRCGHYYCSACAIKRPKCLACGAPTGGIF Copci DYQPDVCKDYKETGFCGFGDTCKFLHDRGTYLAGWQLDKEDIPFACLICRKPYPIVTRCGHYFCSACAIKRPKCLACGAPTGGIF Croqu1 DYQPDVCKDYKDTGFCGFGDTCKFLHDRSDYMHGWQLDDEEIPFACLICRKPFPIVTKCQHYFCSNCAIKRPKCFACGSSTNGIF CryneH991 DYQPDVCKDYKETGFCGYGDSCKFLHDRGDYLAGWQLDKEEVPFACLICRQPFPVVTKCGHYFCMGCAAKRPKCYACGAPTQGIF Crypa2 DYAPDVCKDYKQTGFCGFGDNCKFLHSREDYKQSWSLDRENIPFVCLICRGPYPVVTRCGHYFCEPCALQRPSCAQCSAGTNGVF Debha1 DFQPDVCKDFLQTGYCGYGDTCKFLHIRDELKQRKPIEKEQVPYRCVLCSKDYPVKTECNHLFCQKCFMNRPNCFICGKDTGGVC Dekbr2 DYERDVCKDFLLNGYCGFGDSCKFLHYREEYTPVKEKKS------------------------------KR-------------- Dicdi DHQPDVCKDYKQTGQCTFGDACKFLHDRSDYKSGWQIDKQQFPFACFICKKQYPVQTKCKHFFCEDCALTHKKCALCGEPTLGTF Dmel DYQPDICKDYKETGYCGFGDSCKFLHDRSDYKAGWQLEMETLPFKCHICRQSFPVVTKCKHYFCEKCALAQQRCIICSQQTNGIF Enthi DYQPEICKDFYETGYCGYGENCKFIHDRSLTKSSLTLERQKKETICPKCQKKYPMIMKCGDWICSDCAI--KKCPVCNNSTGGVF Falba DYQPDVCKDYKETGYCGFGDNCIFLHDRSNYKSGWQLEQEEDPFACFICRQVFPVKTPCGHIFCERCALRRNTCAICQAPTRGAF Fomme1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLAGWQLDKDDIPFACLICRKPYPVVTRCGHYFCSACAIKRPKCIACGTATGGIF Fusgr1 DFKPDICKDYKKTGHCGFGDSCIFLHDRTDVKQGWQLDKEKIPFACIICEGPYPIVTRCGHYFCEPCALKRPTCASCGAGTNGVF Galma1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLAGWQLDKEDVPFACLICRKHYPVVTRCGHYYCSACAIKRPKCLACGTPTGGIF Ganpr1 DYQPDICKDYKETGYCGYGDSCKFLHDRGDYKAGWIIERDDVPFACLICRKEFPVVTKCNHYFCERCALSNPKCFACGASTGGVF Gloin1 DYQPDICKDYKETGYCGYGDSCKFLHDRGDYKSGWQLEREELPFACYICRQEFPVVTKCGHYFCERCALQNPKCYSCGAPTNGIF Hisca1 DYSPDVCKDYKLTGYCGFGDGCKFLHAREDYKAGWELDRENIPFACVICKKPYPIVTKCGHYFCESCALQRPSCAACGAGTGGVF Klula1 DYQPDICKDFQKTGYCGYGDSCKFLHSRDDVAGGWKLNTEEIPFRCFLCKKEYPVVTKCNHYFCSSCFMKQTNCPICGKETEGAA Lacbi2 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLAGWQLDKEDVPFACLICRKHYPVVTRCGHYYCSACAIKRPKCLACGAPTGGIF Lenti61 DYQPDVCKDYKETGYCGYGDTCKFLHDRGTYLQGWQLDKEDIPFACLICRKAYPVVTRCGHYFCSACAIKRPKCAACGAPTGGIF Malgl1 ----------------SFG-----------------VDLDNIPFACLLCREPFPIVTLCGHYFCAKCAIARPKCFACGAKTNGLF Mellp23 DYQPDVCKDYKDTGFCGFGDTCKFLHDR-----------EEVPFACLICRQPFPIVTKCQHYFCSGCAIKRPKCFACGAPTSGIF Mnele DYAPDICKDYKETGFCGFGDSCKFMHDRSDYKSGWQLEREDLPFACYICREKFPVVTKCKHYFCESCALKQKRCFVCDVNTGGVF Monbr DYQPDICKDYKETGYCGFGDTCKFLHDRSDYKAGWEIDRDELPFACFICREPFPVVTPCNHYFCEKCLLAHKKCYVCSEPTNGVF Morel2 DYQPDICKDYKETGFCGYGDSCIYMHDRGDYKAGWQLDQDDVPFACLICREPFPVVTKCNHYFCEKCALKRPKCAACQTPTGGLF Mucci2 DYQPDICKDYKETGFCGYGDTCIFLHDRGDYKTGWQLEKEELPFACLICRQEFPVVTRCGHYFCETCAIKNPKCFACGAPTQGVF Mydma DYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQLERDALPFACFICRNSFPVVTKCKHYFCELCALEHRRCYVCAEQTSGVF Neucr2 DMAPDVCKDYKQTGFCGFGDNCKFLHAREDYAHGWQLDKENIPFACIICRGPYPVVTRCGHYFCEACALKRPSCAACGSGTNGVF Orpsp11 DYQPDICKDYKETGYCGYGDSCKFLHDRGDYKSGWQLDREELPFACLICRKDFPIKTKCGHYFCEKCAMENKKCFACNAYTYGQF Pench1 DFAPDVCKDWKQTGYCGFGDSCKYLHSREAYKAGWELDRESIPFACLICLKPYPIVTKCGHYFCEACALQRPSCAACGEGTGGVF Phybl2 DYQPDICKDYKETGFCGYGDSCIFLHDRGDYKSGWQIEKDELPFACLICREEFPVVTKCGHYFCEECALKNLKCFACGLPTQGVF Picst3 DFQPDVCKDFLQTGYCGYGDTCKFLHIRNELTRTKPIDKETLPFKCVLCKDDYPIKTQCGHLYCKKCFMDRLKCFICDKETNGIV Plicr1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLAGWQLDKEDVPFACLICRKHYPIVTRCGHYFCSACAIKRPKCLACGAPTGGIF Polpo DYQPDVCKDYKQTGQCSFGDTCKFLHDRSDYKAGWQVEREELPFACFICRKPFPVMTK--------------------------- Pucgr2 DYQPDVCKDYKETGYCGFGDTCKFLHDRGDYMHGWQLDDEEVPFACLICRQPFPIVTKCHHYFCSGCAIKRPKCFACGTPTGGIF Punst1 DYQPDVCKDYKETGYCGFGDTCKFLHDRGTYLQGWQLDKEDVPFACLICRKHYPVVTRCGHYFCSACAIKRPKCLACGAPTAGIF Rhior3 DYQPDVCKDYKETGFCGYGDSCIFLHDRGDYKTGWQLEKEELPFACLICREEFPVVTRCNHYFCEACAIKNPKCFACGLATQGVF Rhoto1 DYQPDVCKDYKETGFCGYGDTCKFLHDRGDYLHGWQLDNDELPFACLICRKPFPVVTLCGHYFDSACAIKRGKCFACGASTNGVF Rozal11 DYQPDICKDYKETGYCAFGDSCKFLHDRGDYKFGWQLDKDDLPFACAICRDPFPIVTKCKHYFCEKCALKQKKCYVCSQPTDGQF Sacce1 DFQPDVCKDYKQTGYCGYGDSCKFLHSRDDFKTGWKLNQEKIPFKCTLCKEDYPVVTNCGHYFCGSCFAKDTKCFICHKETHGSA Salro DYQPDICKDYKETGYCGFGDTCKFLHDRSDYKHGWQIDRDELPFACFICRERFPVVTKCKHYFCEKCLLEHMNCPVCNEKTGGFF Schco3 DYQPDVCKDYKETGFCGFGDTCKFLHDRGTYLAGWQLDKEDIPFACLICRKPYPIVTRCGHYFCSACAIKRPKCLACGSPTAGIF Schpo1 DYQPDVCKDYKLTGYCGYGDTCKFLHMREDYKAGWQLDREDIPFVCLICKKDYPIATTCGHHFCEQCAITRPTCIQCGADTKGLF Sorma DMAPDVCKDYKQTGFCGFGDNCKFLHAREDYAHGWQLDKENIPFACIICRGPYPVVTRCGHYFCEGCALKRPSCAACGAGTNGVF Sphar DYQPDVCKDYKETGYCGFGDTCKFMHDRGDYKTGWQLDREEIPFACYICREEFPVVTRCEHYFCMKCALEH-------------- Spipu1 DYQPDICKDYKETGFCGYGDSCKFMHDRGDYKSGWQLDKEDLPFACVICRNDFPVVTKCKHYFCESCALKHPKCFICGSATQGLF Sporo1 ------------------------------------------------------------------------------------- Stehi1 DYQPDVCKDYKETGFCGFGDTCKFLHDRGTYLAGWQLDKEDVPFACLICRKPYPVVTRCGHYFCSACAIKRPKCAACGAPTGGIF Tapde11 DYQPDVCKDYKQTGFCGFGDTCKFLHDRGDFKQGWQLDKTEIPFKCVICKQDYPIITKCGHYFCESCAIQRAACAQCGTGTGGLF Thetr ------------------------------------------------------------------------------------- Treme1 DYQPDVCKPYKETGFCGYGDSCKFMHDRGDYLAGWQLDKEDVPFACLICRKPFPVITKCGHYFCMNCAVARPKCYACGAPTSGIF Trire2 DYAPDTCKE---SLYCGFGDNCKYLHAREDLKAGWQLDQENIPFACIICRESYPIVTRCGHYFCLPCALQRPTCAACGSGTNGVF Umbra1 DYQPDVCKDYKETGFCGYGDSCIFMHDRGDYKSGWQLEKDELPFACLICRQEFPIVTKCGHYFCEKCAIKHPKCFACGASTNGIF Ustma22 DYQPDVCKDYKETGYCGFGDTCKFLHDRSDYLAGWQLDVDDIPFACLICRKAFPVVTRCAHYFCSSCAIKRSKCFACGQQTGGLF Walse1 DFQPDVCKDYKETGWCGYGDTCKFLHDRSDYMAGWQLDQEDLPFACLITREPFPVVTKCGHYFEKKAALKRPKCYACGTPTGGIF Zygro1 DFHPDVCKDFKQTGYCGYGDSCKFLHSRDDFKTGWKMNQEGIPFKCLICKEDYPIVTNCGHYFCSSCFTQRPNCAICGQDTHGVA [Cluster2198.fasta_al_trimmed; alignment length = 303] Allma1 DLVGRGLVSSITLYCGIDPTADAPHIGNLLPMTCGLRFLTHGHSVISLIGGATGAIGDPSGRSTERNALGHNVAGLTHQVHRFYTNYAERRVVNNADWYANMSLVDFLGDVGRSRVSAMLSRESVRARMGISFTEFAYQLLQAHDFHCQLQIGGSDQWGNIVAGLDMIRKAFGLTLPLVTTASGEKFGKS-AGNAVWMDTSVFDFYQFFMRT-QDADVEQYLKYFTLLPLKEIDD-LIMEHDKL-PAQKTLADEVTEMTELMYVLAAFIAELCGACSSKSEAVKLAKRG--GLYLILRTGKAN Ashgo11 ELRARGLVQQISLYCGADPTASSLHLGNLMPLMVLLHCYVRGHDVVALIGGATGMVGDPSGRSTERTALAENVRRISGQFKRFFENYHGSRVVNNVEWWKDMGLLDFLARYGRIRVQNMLGRDSVSARLGMGFNEFSYQILQAYDFGVAIQVGGGDQWGNITAGIDLIGRAFGVTVPLLLTASGAKFGKS-AGNAVFVDTPSYQLYQFFVNT-SDADVARFLRLFTMLPLSAIDE-AVAAHTVA-PAQRLLAREVVDLSDVLFLLRLFLVDLM-TGSSRAEARRKLVQG--AVYLLLRIGKQQ Aspfu1 HLEERGLIHDVVIYVGVDPTAPSLHVGHMLPFMVLAWGYVWGLPVTYLLGGATSRIGDPTGRLKGREAMDANMASMHMQLKKLGASYGRKHLVNNNTWWNSTSLLEVLRDLGATRLGPMLGRETVKNRMGMSFAEFTYPLLQAWDWGVQVQVGGSDQYGNILFGMDAVKSPIGFTTPLLTAANGEKFGKS-AGNAVWLDTSTFELYQFFVRT-PDDVVERYLKLFTFLPLPKIAE-IMEEQNKD-PAQHTLAAEFLELHRQLFYAPQTFHKILGLVSSKSEGHRIVANK--GAYVLLKLGKWK Aurde31 ------------LYLGIDPTARSLHVGHLIPLLCLLHFRQSGHNSIALVGGATGQVGDPSFRTNARDAMSDNIAALDNQLHTFFRRKLSSFVLNNASWHGDLRLMDFLARAGSAPVCSMTSRA------GLNYREFTYQLLQAYDFDCVLQIGGADQWGNIITGLDLIRRVFGLTTVLLTTSSGDKFGKS-AGNAVWLDTSVFDFYQFWLRT-TDEDVEKHLKLFTFLSMDRISD-VMDQHHTRGEAQRVLADEMTDLTQLFFVLRVLVASLAQLVASNSAAKQLVGLG--GLYLVLRAGKDK Batde5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 ELNSRGFIAQLTVYLGADPSARSLHVGNLLALVGLLHFQMRGHQVISLVGGATGAVGDPGGRTTERKLLTENTASITRQVHAIFEHYARKRVLNNLEWLGGMGFLEFLRTVGKAKVNVMLTRDSVKSRLGISFTEFSYQLLQAHDFGCRLQIGGSDQWGNIVAGIDMIKRAFGLTIPLLTTASGEKFGKS-AGNAVWLDTSVFDFYQFFLRV-ADADVSKYLKLLTFRSVDEIDT-LMAEHERH-PAQRMLASEVTELTRALFVIKALLTKLSKQTRSRSEARKLLLAG--GLYLILRAGKDN Botci1 ILEERGYVHQITAYVGVDPTAPSLHVGHLLPFMSLFWMYIHGYHTVSLVGGATAKIGDPTDRLTTREKMKENILKMHYQLKGIWLNYGRKYLVNNHHWMNKLTVMELLQILGPMRIGAMIAKDTVKNKMGMSYSEFSYPLLQSWDWGITMQIGGSDQYGNITAGIDAVKYPIGFTVPLLTTSAGAKFGKS-AGNALWLDMSSFDLYAYFLRT-SDQDVERYLKLFTFMPMEQINK-TMEEHMKE-PAQHALARDFLELHRLLF-TGNIIARIVGLCATASEANRLCGAS--GLYVVLRRGKSN Caeel ----------------------------------------------------------------------HNSRKVTDQICKIFEN-----IVNNNDWLGKISLRDFLRECKNMQVGKMLRMNTIKNRLGLSYTEFSYQTMQAFDWGCRFQLGGYDQLGHLDFGAHYIKKAAGVCFPILTDSTGAKLGKSEGGGALWLDTSPFHFYQFFAQL-HDDKAEELLLLFSLQDIEHIRD-VLKNHRSN-LAQRELAAEITRITKAMFVLQLFMGQLARLGSGKGHL--LMQQG--AFSVLVCWGKRG Canalb1 YLQSRHLIESITLYCGADPTASSLHLGNLLPLMVLLHFKMSGNDVVGLVGGATGLVGDPSGRKTERNKIDDNVTKIQRQISTFLSNYAKSRSVNNASWWENVKMLEFLATYGRIRVSSMLARDSIQSRLGIGFNEFTYQILQAYDFNVNMQVGGNDQWGNITAGIDLISRAYGLTVPLLTTSSGEKFGKS-AGNAVFIDTTPYQMYQYFINV-PDDIVGKLLKVFTLLPLNVIEGELLPKHNSD-PAQRVLAREVVDLTGFLFLIENFLSALL-VGKSKGEMRRLIKAG--GVYMLVRVGKQN Cangl ELRDRGLVSQVSLYCGVDPTAKSIHLGNLVPLMVLLHFYVRGHDIVTLVGGATGCVGDPSGRTTERSLMESNVSSISGQLEKFFINYYNTKKENNYNWWKDVKMLDFLANYGRIRVQSMLARDSVTARLSLGFNEFTYQILQAYDFGVSIQVGGNDQWGNITAGIDLISR-YGVTVPLLQTASGEKFGKS-AGNAVFIDSTPYDIFQFFLNT-LDEDVPRFLKTFSFLTIEEIES-MTKRHNEK-PGQKMLAKEITDMSNIIFLIDMFLVALV-THSSKSEARRKIEQG--SIYLLLRIGKQK Capow ELQWRGLLHAHTLYAGFDPTADSLHAGNLLVLMGMLHFHRAGHQVIALVGGATGQVGDPSGRQTERSMLASNAAG----------------VVNNLDWYAPMNVLEFVRDVGQFRMTTMLGKESVKSRLGMSFTEFTYQLFQAYDYQCRLQLGGSDQWGNITAGCDLIRKAHGVTMPLVTTSTGEKFGKS-MGNAVWMDTTPFEWYQFFLRS-EDSQAERYLRYYTFLSLDEITD-IARRHAEA-PAQTALADQVTLLTKLLYEVAALLIDALGLTPSKSEAKKLIRNG--GVSVLLRVGKRA Catan2 DLQARGLIHAVTLYTGIDPTAPSPHIGNLLPLTASLRFLLHGHNVLALIGGATGSIGDPSGRATERSSLSANEAGITTQVHRFFENYATRRVVNNKHWTSKLSLIDFLDQVGRARVSAMLARDSVASRMGISFTEFTYQLVQANDFGCTLQIGGSDQWGNIVAGLDLIRRVFGLTLPLVTTSTGEKFGKS-AGNAVWLDTSPYDYFQFWMRT-HDADVGTYLKMYTLLPLDHIAH-VMHAHAQR-PAQNVLASEMTELSGMLFVVAAFVAEVFGACRSKSEAIKLAKKG--GLYLLLRTGKSN Cioin KLHERGILQDIYFYCGFDPTADGLHVGNLLSIMVLLHCQRAGHNVIAVIGNATVRAGDPSEHTKDRNMLSDNVNAIQDCIAKIADTYIYDNILFNQTWYKELNAIDFISTACRFRIGPMMEKRYIKDRIGLMLAEFMYQVLQAYDWNCTFQVGGVDQLGNINAGQQLIRKVYALLTPLVTNLRGQKLGKT-AGNSVWLNTPPFEFYQFFFKQ-PDSMVETFLKYFTFIDLKRINE-IMIEHTKH-PAQRILAKHVCKLTRALFIMTTFVYDVAKAIPLGNKGENLIRAG--GVRIVLSVGKTN CocheC53 VLEERGFVKDVAVYVGVDPTAPSLHVGHLLPLMALYWMYLHGYYTVSLLGGGTVQIGDPSGRTTARSRQAMNVESIQRQLEKLWTN-----ILNNRKWLEKLSAVELMRDLGSMRLGAMLSRDSVKLRMGMAISEFSYPLFQAYDWGVQLQIGGSDQYGNIIAGMNAVSHTYGLTTPLLTTASGEKFGKS-AGNAVWLDLNSFDLYQYFMRT-ADADVERYLKLFTFLPLDSIKL-LMSQQSQD-PAQHILAREIVELHKDAFYKQAYFPHILGLATSRSEASRLIAKK--GAYVVLRAGKAK Coere1 ----------------------------MVTLMGLLHFHLAGHQAIPVVGSATGMIGDPSGRSTERAALEQNVSGIEAQLQRFFVRYAAGRVLRNGEWYSGMGVLEFLGNVGRARIGMMMARDSVRTRLGISFTEFSYQLLQAYDFGCRIQVGGSDQWGNITAGTDLIHRAYGLTIPLLTTASGAKFGKS-AGNALWLDTSAFDVYQFFVRT-TDGDVEKHLKQLTLLPLERISQ-TMVEHARA-PAQRLLAAEVTELTEVLFFAQAFIDAIAGACKSKAEAARLARGG--GLYWVIRTGKAN Conco1 ELKGRDLISSTSVYLGVDPTATSLHVGNLVALTTLLRFQQYGHPIVSLIGGATGYIGDPSGRSTERTLLTTNFKGIETQLTNFFDRHIPNSLLNNYDWYKNMNVVEFLTKVGKARVSTMLSRSSVKSRMGISFTEFSYQLIQAYDFGCAIQIGGNDQWGNIVSGIELIHKAYGITLPLLTTSSGEKFGKS-AGNAIWLNTSTYDFYQFFLKA-ADDEEN--------------------------PAQKTLAKSVTELTSILFLISALIVDIAKLISSKGFGKKLIQSK--GLYILLRSGKSN Conpu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci EVTARGFIQDVTLYTGIDPTAPSLHIGHLIPLLCLAHFHLHGHKIIPLIGSATGRIGDPSGRSTERKLQQANIAGLTRSVTNFFERHASRRVVSNHVWHEKFSMLDFLQVVGIARINTMMNRESVRARLGISFTEFTYQLLQAYDFGCTIQIGGSDQWGNIVAGIELIGKAFGITTPLLTTPSGEKFGKS-AGNAVWLDTSVFDFYQYFFKS-PDSVLPLYLNLFTFLPRPKIAE-IVETHNAR-PGQKTLAAEVTEMTSLLFITSAFVVKLAGLVASNSAGRSLVASR--GLYLILRAGKDK Croqu1 DLENRQLIAQVTVYLGIDPTANSLHAGNLLALIGLLHFTLHGHNSIVLLGGGTGAVGDPSGRSSERTTLSENLNALQRQVQRLLTSHAQTRVKNNLEWLSELTLLDFLGSVGKARVSSMLARDSVKHRLGISFTEFTYQLLQAYDFGCTVQLGGSDQYGNIMSGIEIMTK-YGVTMPLLTNSKGEKFGKS-AGNALWLSTPPVDLYQAFLRT-PDSEIHKYLRMLTFLPLEEIDR-VMDEYKEG-DPQKLLAREIISLTAFLFLKLAFIESLANLCKSKGEARSLRQSG--AITILLMRGKTA CryneH991 ----------MPIYAGVDPSASSLHVGNLIPLLGLLHFQARGHQSICLIGGATGSIGDPSGRSTERKSLTLNIAGITSQVHRFFIRYLSKRVMNNYDWMRDVGLLDFLRTTGKARVSTMLSRDSVKNRLGISYTEFTYQLLQAYDFGCNIQLGGSDQWGNIVAGIDLIRRVYGLTIPLLTTSTGEKFGKS-AGNAVWLDTSAAEFYQFFLRT-TDEDVEKYLKLFTFLPISRIQD-VMHAHQTS-KPQKLLAAEVTELAQVLYVLDAFVGKVAGLCGSVGETQRLVQSS--ALQVIVRAGNKR Crypa2 EFEERGFVKDVVAYCGVDPTAPSLHLGHLVAFMPIFWMYLHGFGSFILIGGSTAKIGDPTGRTESRPEIRQNLASIQYQLKAVWEHNGRRFVINNNAWWNKLPMLDVLKRLGSVRLGPMLGRDNVKKRIGMSFAEFSYPLMQAWDWTVQLQIGGSDQYGNILTGAQAVKYPIGFTVPLLTDSAGTKFGKS-AGNAIWLDTSPFDMYGYLVRR-PDDDVERLLKLLTFFPLSDIAK-FMEEHKTN-PAQHLLAYEVTALHRTRY-GHPTLARIVGLATSVSDADRTIKNG--GIYILLRKGKHN Debha1 HLQSRYLVESITLYCGADPTAESLHLGNLLPLMVLLHFNLRGHDVVGLVGGATGAVGDPSGRTTERTQLADNVNRIQNQLSNFLKQYAKSRTENNAKWWESIKILDFLSTYGKIRVSAMLGRDSIQSRLGLGFNEFSYQVLQAYDFKVNLQIGGNDQWGNITAGVDLISRSFGMTVPLLTTPTGEKFGKS-AGNAIFINTTPYQLYQYFINT-PDEIVAKLLKVFTILPMATIEK-IVQKHNED-PAQRILAREVTDLTSFLFLISVFLSTLL-MKKSKTETKNLIAAG--GIYLLVRAGKQN Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ILKKRGFIHQMTLYAGFDPTADSLHIGNLLTLMVMLHFKRHGHNPIALMGGATALIGDPSGKSSDRVMLTGNLKHIRENITAVLGE-----VVNNIEWNKTMDVISFLREVGSFRVGSMIKKDFIQNRLGISFTEFCYSLFQANDFGCSIQIGGSDQWGNITAGCDLIRKAQGITIPLLTNSAGKKLGKS-EGNSIWLSTSPYKFYQYWIQV-SDEDVERLLKLFTLIPLEEISI-LVQKHNEN-PGQKTIAEHVTRLTELLFLLSRVILNLF-SDASKSKVKQLLQSK--SIYLYLKSGKKI Dmel ELTDRGFFHGIFIYAGFDPTADSLHVGNLLVIMGLIHCQRAGHRPIALVGGATGLIGDPSGRKTERNQLGTNLKAIEQQLRRVFENLWDSKIVNNADWYADLQLIDFVANMGRFRMGSMLSRSSVQSRLGMSFTEFTYQIFQAYDWNCCFQMGGSDQTGNLMTGHELISRVFGLTLPLVTTEEGDKFGKS-AGNAVWLDTSPFALYQFFLRM-PDSEVEKLLKLFTFIPLPQVEQ-LMREHTKE-PAQTLLAEDVTLLTNALYIQQTFILELAKCFPTETDAVRIINAG--GFYVLLRVGKRN Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ELTQRSLIAGIT-YSGFDPTASSLHIGNLISIIVLSHFASFGHHAVGLIGGATGEVGDPSFRTTSRTHQASNASSLEQQLATLLLRLALSHLLNNRRFYEGLGLLDFLRDVGSVRVQQMIGRDSIRSRLGLSLAEFTYQILQAYDFSCRVQIGGSDQWGNIVAGVDLIGSAIGMTTPLVTDSQGRKFGKS-LGNAIWLDTSPFHLFQFFRHAVPDADVGRMLQYYTFLGPASIQA-VLNAHADT-LAQNVLAFEVTRLSRLLFAITALVAGLCGLCASRGEAIRLATQG--ALYVVIRAGKRP Fomme1 DLKLRGMISQTTIYLGIDPTAKSLHVGHLLPLMVLLQLFLRGHEVIPLIGGATGLVGDPSGKTEERSPLGDNVESLTRAVDGFFASYGSKRVANNVEWLGSLGLLEFLTKAGRARIPTMISRDSVKIRIGLSFTEFTYQLLQAYDFGCTLQLGGSDQWGNILAGVDLIDRAHGLTTPLLTTVSGAKFGKS-EGNAVWLNTSVLDFYQFFVRT-ADADVGKYLYMFTLLPTHDIAD-ILKKHEAA-PVQRRLADEVVELTQALFIVTALIWKLAKLSSSNSEARRLATSK--GLYLVLRAGKDN Fusgr1 ILQERGYIKDVASYVGIDPTADSMHVGHLLPMMPMFWMWFHGYPAVTLIGGSTARIGDPTDRLESRQILSKNITKIHLQLTRIWSNLKEKYLLNNNMWLGNLTLYDFAKRIARTRIGPMLAKDTVKRKMGMSLGEFMYPLLQGWDFGIQMQIGGSDQYGNITAGIDALKTPVGFTVPLLTDASGAKFGKS-AGNAVWLDTTAFDLYGYFVRR-SDDEVEKLLKMFTFMPMETIST-LMEQHRAN-PAQHALAFDVVSLHEFRF---IIPAKILGLASSSSEGNRLLSQQ--GAYIIMRKGKHN Galma1 ----------MGVYVGVDPTAKSLHIGHLIPLLCLLHFQIRGHAIVPLIGGATGRVGDPSGRLVERQLAEGNVVSLTSSIQRFFKNYAES-VISNLDWHGSFNLLEFLQKVGVARVNTMLNRESVRTRLGLSFTEFTYQLLQAYDFGCTIQIGGSDQWGNIVAGLELIGKCFAITTPLLTTSTGEKFGKS-AGNAVWLDTSVFDFYQYFLKV-TDADVGSYLSLFTLMSQEDITG-LLEMHKSA-PAQHRLADEVTEMTKLLFILASFVAKLAGLVMSNSVARNLVASS--GLYLILRAGKDK Ganpr1 LMKERGLIQGVTVYCGFDPTARSLHVGNLLQIVGLLHFWRCGHSIVALLGGATASIGDPSGRSTERPLLDLNTASIEHQLQSLLATHIVRKIANNHSWHSKMSFLDFLRDIGRARVGTMLSRESVKSRMGLSFTEFSYQLLQGYDFKVKVQMGGSDQWGNIVAGVELIRRTWGVTLPLVTTATGEKFGKS-AGNAVWLDVSHFDFYQFFRRT-PDSEVERYLKYFTFLPLSEIEE-VMAEHAKA-PPQRTLAAEVTEMTRLLFILAAFVVRVAGVAKSKTQALKLLTSG--GLYIVLRTGKSN Gloin1 ELKKRGLINALTIYCGVDPTAPSLHLGNLLTLIGLLHFNVRGHRTIALIGGATGSIGDPSGRNTERQPLSKNANAIDNQIRKIFINYALRRILNNLKWFQKMSALELLNDIGRARVGTMMARDSVKLRMGISFTEFSYQLLQAYDFQCQIQLGGSDQWGNITAGIDLIHKAFGITIPLLLTSTGEKFGKS-AGNAIWLDTSPYEFYQYFMKL-ADADVEKYLRMFTILSMEEIDQ-IVKTHMKS-PGQEKLASEITEFTRVLFLIEAFIDRVAGACKSRNEANKLIKVG--GLYLVIRTGKSN Hisca1 LMEERGLVNAVIVYVGVDPTAPSLHIGHMLPFMVLAWAYVHGIRAVFLLGGSTSQIGDPTDRLGPRAKMAENMANMHLQLKRLGMSYGAKHIVNNNTWWLKEPFFEVMKTMGEVRLGPMLGRDTVKNRLGMALSEFVYPLLQAWDWNVLVQVGGSDQAGNIQFGMDATKPPMGFTTPLLTTPSGQKFGKS-AGNAVWLDTSSFDLYQFFLRV-PDENVEQYLKYFTFLPITAIKE-LMERHVQD-PAQHKLASEFVELHRSIFTLPETFHKVLGMAPSKAEAFRLIVNN--GASV-------- Klula1 VLRERGLVQQVSLYCGADPTAKSLHLGNLLPLMVLLNFYVRGHDVVSLIGGATGKVGDPSGRKTERDVIAGNIERIVEQYKTFFTNYYESRYLNNISWWQDVKMLDFLATYGKIRIQNMLSRDSVSSRLGIGFNEFTYQILQAYDFQVSIQVGGNDQWGNITAGIDLINRAFGLTVPLLTTSTGEKFGKS-AGNAVFIDNTSYDMYQFFVNT-TDADVAKQLKIFTLLPLELIED-IMAQHALS-PAQKRLAKEVVDLSRILFLIRVFLSDIV-IDCSKTESRRRIKQG--SIYLLLRVGKQK Lacbi2 DLVRRGFIHDVTVYAGIDPTASSLHVGHLIPLMCLLHFHLRGHRVIPLIGGATGRVGDPSGRSVERQLADNNVQCLQKSVRSFFSRYAETRVESNLKWHSQLTMLDFLQSVGIARVNTMLNRESVRARLGLSFTEFTYQLLQAYDFNCSIQVGGSDQWGNILAGLELIGRAYGITTPLLTTSSGEKFGKS-AGNAIWLNTSVFDFYQYFLKV-SDADVERYLNLFTLMTSQDIQN-VMGVHVDH-PAQRRLAAEVTEMTGLFFILLALIYKLAGLASSNSAARALVASR--GLYVIMRAGKDK Lenti61 DLRARSLVADITVYLGVDPTARSLHVGHLVPFLCLLHFQLRGHQIVPLIGGATGLIGDPSGRSTERPLSAYNVGQLTQGINQFFTRYAEKRVQNNLNWLKDLNLLEFLRTVGFSRVNTMLSRDSVSARLGISFTEFTYQLLQAYDFGCTIQIGGSDQWGNIIAGVELINRGFGITTPLLTTASGQKFGKS-AGNAVSLNTSVFEFYQFFLRS-SDADVGKYLKMFTLLPLEQVES-VMEAHNKT-PAQRLLAEEVTELTKILYVIAALLTKLARLAASNSAARQLVTAK--GYYLFLRAGSQK Malgl1 VLESRGMVQATTIYSGVDPSAPSLHVGNLLPLVALLHCAIYGHKALVLIGGATGAIGDPSGRSSERSALGSNVTTIRAQIFQFFHNYLSRRLVNNLDWFRDIKMLDFLSSVGRVRVNDMMARDSVKSRLGLSFTEFSYQLMQAYDYGCSVQLGGSDQMGNIMAGIDLIRRAYGLTLPLLMTSSGVKFGKS-AGNAVWISLSDLDFYQYFVRS-ADADVERYLTSLTFMPLEEIKQ-VMILHSQD-RAQICLANEMTELTKVLFILYAFLLRLAGLVSSRSEARRLVQQGSSGLYVVMRAGKSN Mellp23 KLESRQLIAQLTIYLGIDPTASSLHVGNLLALIGLVHFALNGHKTIVLLGGGTGIVGDPSGRSSERTSLSSNVECLHKQVNKILDSHAQTRVKNNMEWLSGLTLLDFLGSVGKARIASMLARDSVKQRMGISFTEFTYQLLQAYDFDCTIQLGGSDQYGNIMSGIEIMTK-YGVTLPLLLNHKGEKFGKS-AGNALWLSTPPVDLYQAFLRT-PDSEIDKYLRMLTFLPLEVINR-VMDDHQKG-DPQKLLAQEIILLTEILHFQDAFIDSIAGLCKSKGEVRSLKQSG--AITVLLMRGKTA Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr NEESRAEAAFQGFYCGFDPTARSLHLGNLLSIMGLLHAALDGHYAVALIGGATGHVGDPSGRNSERDPLSENAISIDLSLQTIFQNMAKETLVNNVAWYERMSVLDFMVKVGKARMHTMLGKDSVKSRLGMSYAEFSYQLFQGWDFLCTIQLGGSDQWGNMLAGIELLRKGHAITLPLMTTAAGVKFGKS-MGNAIWLNTSPYQLYQFLFNT-DDADCAKLLRALTFLPLDHINN-IVADHTAA-PAQRVLAEQVLRLTKVLH---------------------------------------- Morel2 ELQQRGLVSAMTIYCGVDPTASSLHLGNLVTLLGLLHFHIKGHTTIGLVGGATGSIGDPSGKSTERQPMSHNVAGIDAQFQQFFKRYAENRVVNNKTWFGKLSALDFLGDVGRARVGTMIARDSVKSRLGISFTEFSYQLLQAYDFGCRIQLGGSDQWGNITAGIDLIHKAYGLTIPLLTTSTGEKFGKS-AGNAVWLDTSLFDFYQFFVKT-ADADVGRYLHYFTLLTSEQIQD-VMTQHNAE-PAQHALAKETTELTQVLFLIDAFLDRIAGLCSSKSEAKKLVKSG--GLYIVLRSGKSN Mucci2 DMTHRGLVSNVTIYCGVDPTAKSLHLGNLVTLMGLLHFHVRGHQTIALVGGATGSIGDPSGRKSERVPLSINVAGIESQIHRFFKNYAQRHVLNNYNWFSSMTAIDFLSSVGRARVNTMLAKESVKSRMGISFTEFSYQLLQAYDFQCRIQLGGSDQWGNITAGIDMIYRAFGITIPLLLTSTGEKFGKS-AGNAVWLDTSVFDFYQFLMKT-TDSDVGKYLEMFTFLTKEQVSD-IMAQHQQS-PAQTALANETTELTRVLFIIEAFLDKVANAAKSKSDAQKKMKAG--GIYLVLRSGKSS Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LFEERGYVKDTAAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAKIGDPTGRLKSRDHLSMNMTKIHYQLKKLWENQMRARIVNNNHWWNKQPMLEVLRRVGHLRIGPMLSRDTVKNKMGVSFAEFTYPIMQGWDWGVQMQIGGSDQYGNIISGLEVVKACVGFTVPLLTDSSGAKFGKS-AGNAIWLDTSVFDFYGYFVRR-SDQEVENLLKLFTFMPISEITK-TMEEHIKD-PAQHTLAREVVTLHRMMY-DQPVIGRILGLASSTTEGHKLAAAQ--GCYVILRKGKHN Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 HLEERGLIHDVVIYVGIDPTAPSMHVGHMLPFMVLAWAYVWGLPVTFLLGGATSRVGDPTGRLKGRDAVHANMASMHMQLKKLGSSYGRRHLTNNNTWWNSMPFLEVLRDLGAMRLGPMLGRDTVKTRLGMSFAEFSYPILQAWDWGTQIQVGGADQYGNILFGMEAVKSPIGFTTPLLTTPSGEKLGKS-AGNAVWLDTSTFELYQYFVRT-PDDVVERYLKLFTFIPLPEIAT-IMEEQNKD-PAQHKLAVEFVELHRQLFYAAQTFNKILGLVSSKSEGHRVIVNN--GAKVMLKLGKWK Phybl2 DLH--------IIYCGVDPTAKSLHLGNLVTLMGLLHFQIRGHQTIALVGGATGSIGDPSGRSSERIPLSVNVAGIEEQIHRFFSNYANRRVLNNYEWFSSMNALEFLGNVGRARVNTMLAKESVKSRIGISFTEFSYQLLQAYDFGCRIQIGGSDQWGNITAGIDMINRAYGITIPLLLTSSGDKFGKS-AGNAVWLNTSIFDFYQFFMKT-ADADVGKYLSMFTLLNQQEIDD-IIKSHQAN-PAQEKLAMETTELSQVLFILDAFLDVLANATQSKSEAQKKIKAG--GMYIVLRVGKSS Picst3 HLQSRYLVESITLYCGADPTAESLHLGNLLPLMVLLHFNLRGHDVVGLVGGATGAVGDPSGRTTERSQIEDNVSKIQKQLVTFLENYAKSRTANNASWWLSIGMLEFLAKYGRIRVSSMLARDSIQSRLGLGFNEFTYQILQAYDFGVNMQIGGNDQWGNITAGIDLISRAYGMTVPLLTSPTGEKFGKS-AGNAVFIDTTPYQMYQYFINS-PDDMVAKLLKTLTLLPLSIIDGYILPKHESD-PAQRILAREVVDLTSFLFLIQNFMSSLL-TNKSRREVKQLIKSG--GIYMLVRVGKQN Plicr1 DLRTRGLVVDVTVYLGFDPTARSLHVGHLLPLMCLLHFQLRGHRIYPLIGGATGLVGDPSGRTVERHLEESRTQTLENSIANFFHGYASARVVNNHAWHKDMHLLEFLRTVGRVRVNGMLSRDSARSRMGLSFAEFTYQLLQAYDFKCAIQIGGSDQWGNILAGLELINRGFGILTPLLTTSSGDKFGKS-AGNAVWLDTSVFDFYQFFVKT-TDADLEKYLKMFTLLSIGEISG-IMHHHNEEGPANRRLADEVTLLTRVLFVVDAMLVRLCGLVPSISAARTLVEAK--GLSLILRAGKDK Polpo TLRSRGFIYQMTLYAGFDPTADSLHIGNLLTLMVLLHFKRHGHKPVALLGGATALIGDPSGKSTDRPQLDNNSSYINENIVDILGK-----IVNNIDWNKSISIIDFFRDVGRFRVGNMLRKDFVHNRLGISLPEFCYSLFQANDFQCVIQVGGSDQWGNITDGCELIKKAYGITIPLLTNSQGKKLGKS-EGNSIWLSTSAYNFYQYWIQV-SDQDVEKLLKLFTLLPLEEIQS-IVDAHNKE-PGQKKIAECVTQLTNLLFLLSGVISSIF-SGLSKNQSKLLINNQ--SLYLILRSGKKA Pucgr2 ELEKRGLIAQVTIYLGIDPTAQSLHVGNLVVLIALLHFTLKGHQTIVLLGGATGSVGDPSGRNSERVALSDNVQSIEKQLEKLLSNHASNMIKNNLEWMKDLSLLEFLGSVGRARVSAMLARDSVKQRLGISFTEFTYQLLQAYDFRCTIQLGGSDQYGNIMSGIELMSKAFGLTIPLLTTREGEKFGKS-AGNAVWLDTSPVEFYQTFISI-PDSEVLKYLKMLTFVPTEELDQ-CLQSSTKN-PLQKLLAREVTLLTEFLFLDETFLGDLSKLFQSKGEARRAIKAG--GVRFLLMRGKSG Punst1 ALTARGFIADITAYSGVDPTADAFHVGHLVPLMCLLHFQIHGHRIISLIGGATGLVGDPSGRIIERQLARGNVSKLTSGIEKFFEKYASSRILNNLTWHKDMSMLRFLREVGSNRVNTMLARESVQTRMGLTFTEFTYQLLQAYDFGCRIQIGGSDQWGNIVAGIDLINRAYGITTPLLTTANGEKFGKS-AGNAVWLDTSPFDFYQFWLRT-ADADVERYLKLFTLLPLTRIED-VMAEQRAH-PAQQLLAREVSELTDVLYIIASMLMVLSGLTRSGGAAKTLAKTN--GFYVVMRTGKRN Rhior3 -MSQ-------DIYCGVDPTAKSLHLGNLVTLMGLLHFHIRGHQTIALVGGATGSIGDPSGRKSERVPLSINVRGIESQIHRFFQNYANRRVLNNYDWFSSMTALEFLSDIGRARVNTMLAKESVKSRIGISFTEFSYQLLQAYDFACRIQLGGNDQWGNITAGIDLISRAFGITIPLLLTSTGEKFGKS-AGNAVWLDTSIFDFYQVL----------KILDSFVF-----VND-------------------------------------------------------------------- Rhoto1 ELEERGMLAELTVYLGVDPSARSLHVGNLLALIGLLHFRLHGHTAVALIGGATGAIGDPSGRSTERNALSSNVESITKQFTTFLERFAQSRVVNNLDWTGSMTLIDFLSSVGKARVSTMLSRESVKSRLGISFTEFSYQLLQAYDFGCTMQLGGSDQLGNIVSGIDLIRRAFGLTFPLLTTAAGEKFGKS-AGNAIWLDTSPFEVYQFFLRT-TDEEVEKYLKIFTFIRVVEIEG-IMQDHKAN-PAQKVLAAEATELTSVFYIIQALLEKLAGLMASKTQARKAIEAG--TIQLVIKAGKTA Rozal11 SLKNRNLLHQSTIYGGFDPTAKSLHVGNALLLMALFRGQIHGLNSIYLVGGATGLIGDPSFKDKERPELSENTKYIMNQIKQWIHNFSSMRILNNADWLGKISFIDFLKRVGKSKVSIMLQRECVKKRMSISYTEFTYQLLQGYDYNCTLQIGGSDQLGNMIAGIDLIHRVFAATLPLLTNDQGKKYGKS-EGNAIWLDCSPFDFYQFFLNS-TDSLLERLLFSFTFLDAAEIAE-ILNEHEKN-PGQIELASHVTELTQLCFLMDAFVADILGICKSKSKTI-------------------- Sacce1 ELKQRGLVSQVSLYCGVDPTAQSLHLGNLVPLMVLLHFYVKGHDIVTVIGGATGKVGDPSGRKTERDVMESNVASISQQLQRFFKNYYRNRPRNNFNWWKDIKMLDFLADFGRIRVQSMLARDSISSRLGLGFNEFTYQVLQAYDFNVTIQVGGNDQWGNITAGIDLINRPFGITVPLLTTATGEKFGKS-AGNAVFIDNTAYDVYQFFYNT-LDADVPKFLKIFTFLNSSEIKK-IVETHIKS-PGQTLLAKEVTDMSNIIFLVDLCLIKLI-VNCSVSEARRKLSQG--SVYLILRIGKQK Salro TLEERGLLKDSTVYCGFDPTARTLHIGNLLAIMGLVHCVRAGHNVIALVGGATARIGDPSGRSTERTCLPANIAGITEVLHRILDNYEASTVVNNAEWYDEWRVIDFIADIGRFRVNSMLAKDSVKSRMGISFTEFTYQVLQGHDFNCRVQLGGSDQWGNITAGIDLVRRVYGVTMPLLTTSTGEKFGKS-AGNAVWLDTSPYELYQFFINM-ADADVERYLAALTLLPVSTIKQ-VMEQHIQQ-PAQHKLASEVVRLTDALFLKAMFILSAAGLFSSKGEAKRTLKAG--GLYVVLRKGRKH Schco3 DLKKRGFVADATVYAGIDPTAPSLHAGHLLYLMCLFRFHAAGHKIIPLIGGATGLLGDPTGRRTARDPANQNVASLEAALRKFFEGYAEARVKSNLEWHKDFSMLDFFMVVGSARMNTMLNKESVRTRLGMSYTEFSYQLLQAYDFGCTIQVGGSDQWGNIVSGLELIARCFGLTTPLLTTASGEKFGKS-AGNAVWLDTSPFAFYQYWILT-EDKDVEKYLKLFTLVSDAEIES-VMQEHNAA-PAQRRLAAEVTELTRLMFVFSALIFSLAGLVASKSEARRLGKSK--GFYVVLRAGKSN Schpo1 QLQARSLIHNTTVYLGADPTAASLHVGNLVALMPLVHFFLNGFPVFTVIGDATAQLGDPSGRSTSRKQMAANSNSIHNQLKDLSSSYAQDCIVRNSSWYENLKLLKFLSSVGPVRVSQMLARDSVTTRLGLSFAELTYQLLQAYDYSVNLQIGGSDQWGNITAGTDLVRRVYALTTPLLTSSSGQKLGKS-AGNAIWLDTDSYSLYQYFISA-PDDLACKCLDMLTLLPLEQLEQ-IKAEHEKD-PVHKYLASNVVRMTKLLHIRALFFSRLLQIYTSRKEATEHILSG--AVSLVLRAGKRT Sorma LFKERGYVKDTAAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAKIGDPTGRLTSRDKLSMNMTKIHYQLKKLWENQMRARIVNNNHWWNKQPMLEVLRRVGQLRVGPMLSRDTVKNKMGVSFAEFSYPIMQGWDWGVQMQIGGSDQYGNIISGLEVVKACVGFTVPLLTDSSGAKFGKS-AGNAIWLDTSVFDFYGYFVRR-TDEEVEKLLKLFTFMPTSEITK-VMEEHVKD-PAQHALAREVATLHRLMY-GQQVIGRILGLASSTTEGHKLAAAQ--GCYVILRKGKHN Sphar ELRERGLWNQCTVYCGFDPTADSLHVGNLLMIITLLHFSRAGHKTIAIVGGATGSVGDPSGRTTERDPLAVNLAGIEQDLKRVFANYAEGTVVDNAEWYADMTPVTFLTEVGRLRLNHMLARESVKSRLGISFAEFAYQALQAYDFDCTIQLGGSDQWGNITAGCELIRRSFGLTIPLLTTAAGVKFGKS-MGNAVWLNTNPYELYQFFINT-TDDDVEKLLRSLTFTPLDEISQ-IMVAHQNA-PAQKALAKSVTQLTDSFFILERYVIDLAGAVKSKGAARRLITAK--GLYLLLRTGKKS Spipu1 ------------V------------------------------------------------------------------------------VLNNFDWFKDIGVLEFLSDVGRARVSIMLSRESVRSRLGISFTEFSYQLLQAYDFRCRVQIGGSDQWGNIMAGMDIIKRAFGLTIPLVTTATGEKFGKS-AGNAVWLDVSHYDFYQFFRRT-PDSEVQKYLRYFTFLPEEDIEK-LMVQHTVT-PPQRTLAREVTELAEVLFILAAFIVQVAGAVKSKSAGRKLLASG--GLYLLIRTGKSN Sporo1 ------------VYLGVDPSADSLHVGNLLVLIGLLHFRLQGHNAIALIGGATGAIGDPSGRSTERNALSANVAGISRQLTTFLDRFAQSRIENNMSWIGGMSLLEFLSKVGKARVSTMLSRESVKSRLGISFTEFSYQLLQAYDFNCTIQLGGSDQLGNIVSGIDMIRRAFGVTFPLLTTAGGEKFGKS-AGNAIWLDTSPFDLYQFFLRT-SDEEVEKYLKIFTFIRVVELKG-IMEDHKAQ-PAQKILAAEATELTKLFYMINALAEKIAGLFNSKTQARKAIEGG--TLQIVLKAGKSG Stehi1 ELDGRGFISQVTIYSGIDPTGLSLHVGHLVPMMCLLHFHLRGHRIIPLIGGATALIGDPSGRSTERPLLSRNIDKLRASVERFFSRYAETKVMNNIEWFEGLGLLQFLRTAGIARVNSMIARDSVQARLGISFAEFSYQLLQAYDFGCTIQVGGSDQWGNIISGIELINRGFGITTPLLTTSSGEKFGKS-AGNAVWLDTSVFDFYQFFVRT-ADEDVLRYLKLFTLLPLSEIEA-IMEKHNRA-PAQKVLADEVTELTKIFFVISALLHKVTGLAASNGAAKKLISMG--GLYIVLRAGKAN Tapde11 ALQERGLVKTITLYCGVDPTAASLHVGNLLTLIPVLHFFMRGHHAYALVGGATGKVGDPAGKSAEREKMASNVDALSAQLTRFFENYASSRVVNNADWYAQLNFMDFMNDVGRVRLQSMLARDSVKNRLGMSFGEFTYQLLQAYDFGVTLQIGGSDQYGNITAGIDLITRAFGLTVPLLTTPSGEKFGKS-AGNAVWLDTSPFDLYQYFLKT-PDTHIEAYLRLFTLLPTGEIAA-IAAQHQEN-PANRILARELLILNRVLFIITAFISSLLGALSSAKEAQQMIVNG--GIHCVLRIGKNK Thetr ---------------------------------MLRRFAAVGVKPVVLLGGATGLLGDPSGKTAERTLMPRNMASIEASLRMQLL------VRNNAEWMAEMGALELLREYGKFRVSAMLARDAVASRLGISFTEFAYQMVQGIDFAVAVQIGGSDQWGNITAGLDLIRRAVGVTYPLLTTADGAKLGKS-AGNAVWLDTSPFDLYQYFALA-PDADVRTLLCALTELSLDTIED-ELAAHFAQ-PAQKTLAAEVTRMSDALYSVVAL-----GLAPSKSAAKRLANEG--GLYLVIKAGKR- Treme1 ELEQRGFIAALTIYAGIDPSASSLHVGNLLPLFGLLHLYKAGHNIIPLIGGATGPIGDPSGRKSERTSLSDNASKITTQVEHFLEHLASRRVLNNLDWFKDIRFLEFLSDVGKARVNIMLARESVKNRLGISFTEFSYQLLQAYDFGCTVQLGGSDQWGNIVAGIDLIKRVYGLTIPLLTTSNGEKFGKS-AGNAIWLDTSVSEFYQFFYRT-EDADVERYLKLLTFIPLPQIEE-IMREHGVS-SGQLKLARELTELARILYVLQAFMTKLAGLVRSRGQSTRAVQTR--GLYLILRVGTRK Trire2 LLDERGYIKDVAAYVGVDPTADSMHVGHLLPMMPLFWLWFHGHPAVTLLGGATARIGDPSGRLQSREILSKNVTKLHYQLSRLWHNLREKYLLNNSMWLQGLTMYDFTKRLARTRIGPMLSRDTVKRKMGMSLGEFMYPLFQGWDFGIQMQIGGSDQYGNIVAGIDALKIPVGFTVPLLTDSAGVKFGKS-TGNAVWLDTSPFELYGYFMRR-SDDEVEKLLKLFTFMPMSKIQE-VMVEHQAD-PAQHTLAFEVLSLHQFRF---ILPAKLLGLVNSASEGQRLVAQQ--GAYVILRKGKHN Umbra1 NMTGRGLVASLTIYCGVDPTARSLHLGNLVTFMGLLHFHITGHQAIALIGSATGTIGDPSGRQSERVPLSDNSSNITQQIHRFFENYAKRRVLNNIEWFKGMSAMEFIGDVGRARVTQMLARESVKARLGISFTEFAYQLLQAYDFSCRIQLGGSDQWGNITAGIDMIHKAFGVTIPLLLNSKGEKFGKS-AGNAVWIDTTLFDFYQFFVKT-ADEDVERYLPLFTLLSPDEIKS-LMHEHKQN-PAQHKLADEVTELTKVLFIIQAFLDAIAGATRSKSETQKLIKSG--GVYLVLRVGKSS Ustma22 ELESRNLIAHVTVYSGVDPSADSLHVGNLLPLLTLAHFARHRHHPIVLVGGATGSIGDPSGRSTERNALSRNVAAITQQVGKFFNHYAESTMMNNYEWMKDVSLLDFLGGVGRARLTQMLARDSVASRLGMSYTEFSYQLLQAYDFACTIQIGGSDQLGNITAGIDLIRRAYGLTLPLLTTCTGEKFGKS-AGNAVWLSTSDWALYQFFVRS-SDADVERYLLSLTLLEPQFVKS-IMQEHQEN-KAQTVLADHMTRLTELLFI----VTKVVGLVKSRAEAKRLLISG--GLYILLRAGKSA Walse1 ELVDRGFVKDTTIYSGMDPTAVSLHAGHLLPLLACLHLHLAGHRIIPLIGGATGSIGDPSGRSTERTLIENNIFNLTKQIESFYENYADKYVLNNKSWLGKLSLLEFLSTTGKSNIGPMLARDSVKNRLGISFTEFTYQLLQAADFDCTVQIGGSDQWGNITAGVELIRRAFGLTLPLLTTSSGDKFGKS-AGNAVWLNTSVFDFYQFWLKV-TDMDVEKYLKLLTLVPLETISQ-IMEQQRAK-PAQRRLADEVTTMTNVLFVVAAFLTKVVPQVKSGSQAKTLIGSG--GVYLFIRTGKSS Zygro1 DLKLRGLIAQVALYCGADPTAKSLHLGNVVPLMILLNFYVKGHDVFALVGGATGRVGDPSGRTTERQGMSDNVDRIQQQFTRFFENYYESRKVDNYHWWKDIKLLDFLAQYGRIRVQSMFSRSSIASRIGLGFNEFTYQVLQAYDFGVSLQVGGNDQWGNITAGIDFIDRPGGITAPLLSTSTGEKFGKS-AGNAIFLDNTAYDIFQFFYNT-KDADVCRFLKIFTLLPLETIST-VVQDHMEQ-PGQRFLAKEVTDLSEVLFLIKLFLVDII-APCSKSEARRKLSQG--SVLLILRIGKQK [Cluster2199.fasta_al_trimmed; alignment length = 99] Allma1 VCTLPPEYCEFNTTKKCKEWLQKNHVDLYNKLTKVIIKSEKRKGKKVVTVITGLDVFGVDLKKASKLFSQKFATGSSVGKQEVVIQGDVAHEVMDLIVE Ashgo11 VCSLPPEYCEFTGKRRCKVWLHEHDQELFAQLSRVVIRREARTKRKCMVVVAGLEVFEIDMKKLAKTFASKFATGCSVSKEEVVVQGDIADEVEAYIHA Aspfu1 VCTLPPEYCEFGGTKKCEEWLKDNHAELYQRLAKVQIKRVERNKRKHVTVITGLEVHGLENKKVAKELGKKFATGSSVTKEEITVQGDVSEDVKEWLLE Aurde31 VCGFPPEYCEFGAHTKCKIWLQDEHSELYDKYAKVIIKRVERQKRKYDTRISGLEQFGVDLKKAAKALAQRFATSASVSKDEIVVAGDVADDVLDIIEE Batde5 HCSVPPEYCEFGTAAECKAWLKTHDQNLFVKLAKVVLSTIERTKRKRITIVNGLEKFDVDLKKAAKQMASKFACGASVSKEEIIVQGEFMDELIKLITA Botbo1 VCSFPPEFCEFGSHTRCKEWLSEAHPELFEKY-QVTIKRIERNKRKHVTSIHGLEAFGVDLKKAAKMFAQKFATGASVTKEEIVVQGDVADEVEELV-- Botci1 VCSLPPEYCEYGGTKKCQEWLEKKYPSMYERLSKIRIKRVERNKRKYVTEVQGLEAFGLELKKVAKEFGSRFATGSSVTKQEITVQGDVSDDVREFLIK Caeel QCSMPPEYCDYSGQDVCRAWATQNAPELLEGLQKVTLQREPRG-KKSVTVIKGLATFDIDLKVASKLFAQKFACGSSVTGDEIVIQGDVKDDLLDLIPE Canalb1 ICSWPPEFCEFGITKKCQTWLNENHPDLYQSVSKIIIKKISRNKKKSIVSISGLEILEVSIKSLQKKFSSKFATGTSVVKSDILIQGDVFEEVHQFIVN Cangl VCTYPIDYCEFSGKKRCKVWLKENHADLYDKLSKVIVKREARTKRKYIVAISGLEVFEIDMKKLAKTFASKFATGCSVSKEEVVVQGDVLDEVVAYIHS Capow VCTLPYEFCHVGPTEECKAKLKALDEAMYEKYKQVTITLENRNKRKFTTSVEGLAQYGIDLKKAAKLFAGRFACGSAVSGDLIVIQGDCVDDLMDYLPE Catan2 ICSLPPEYCEFHPTKKCKEWLQQNNEELYNQLTQVLIKTEKRKGKKVVTVITGLDVFGVDLKAASKLFAQKFATGSSVGKGEVVIQGEVPDEVQELIEA Cioin ECSLPLEYCEFMPEAKCREWREKNL-DVLEQEEVVRIAKIPRGKRKFMTRVQGLATFDVNLKKASKLFAQKFSCGSSVSADEILIQGDVTDDLIILIVD CocheC53 VCSLPPEYCEFGGTKKCEEWLAEAHPDLHAKLSKILIKRIERNKRKYVTAVQGLEAFGLDIKKVAKDFGKKFATGSSVTKEEITVQGDLSEDILEFLVD Coere1 VCSLPPEYCEFSASKKCEQWLMEAHPREHERLSKVLIKRVERNKRKSVTSVYGLHVFGIDLKSTAKMLANHFACGGSVAKDEIVVQGDFSHEILDLLVA Conco1 --------------------------------------------------------------------------------------------------- Conpu1 VCTFPLEYCEFGSSTKCKEWLKEADSAQYDKHSPVTIKRIERNKRKHVTAVHGLEAFDIELKKAAKFFAQRFATGASVSKDEIVVQGDVAYDIEELIEK Copci VCSWPPEYCEFGSHTKCKEWLKDNHSDLFDKYSHVIIKRVERTKRKHVTVIHGLDKFSIDLKKAAKQFASKFATGASVTKDEIVVQGDVSDEVYDMIQD Croqu1 ICSFPVEYCEFGPRSKCRTWLSEQNPEEYARLSKVTVKTVERTKRKRITTVHGLEAFGVDLKKLAKMFASKFATGASVTKDEIVIQGDVSDEVLDLFEE CryneH991 VCSLPTEYCEFGPSSKCKAWLEEQDKNEYERVTKIVIKRSERTKRKHQTHIQNLELFGVDLKKAAKQFAGKFATGSSVSKEEIVIQGDVGDEIVEMIRQ Crypa2 VCTLPPEYCEYGGTKKCQEWLQKTHPDLYHRISTVVIKRIERNKRKFVTAVSGLEAFDLELKKVAKEFGKKFATGSSVTKEEIVVQGDVSDEIEEFLLE Debha1 VCTFPPEYCEFGLSKRCKEWLQENQPELFEKLSKVTIKRIERNKRKHVISISGLEVFNIDMKKLAKTFASKFATGASVTKDEIIVQGDVSDEAKDYIEK Dekbr2 VCTSPVEYCEFGKTKQCKKWLKENHPKEYNNLEKIIVKRIPRTKHKNVIAVCNLEQFDVDMKKLAKKFASKFATGASVSKDEIIIQGDVGEEVEEYLQD Dicdi ICSLPTEYCEYGPSKQC---LKENGPHPNNNKPQIIIEVNQRNKRKHVTKITGLELYGIKLSDAAKVMAKKFSCGCSVVKEDIDIQGDFGEELVDLIEE Dmel HCTMPIEYCEYYPEEKCKEWLELHMPDDFERLKRICVSRAARGKKKSVTVVTGLSTFDIDLKVAAKFFGTKFACGSSVTGDEIVIQGDVKDDLFDVIPE Enthi LCHLPKDLCPYGPNAKCT--------------KVIKIMNVKRNKKQSVTKIVGVLQFGLKQQDVSKFVSKKFSVGANIDKDCINVQGDFVHEIADILAE Falba --------------------------------------------------------------------------------------------------- Fomme1 --------------------------------------------------------------------------------------------------- Fusgr1 VCTLPPEYCEYGGTKKCQEWLEKNEAELYSRISMITIKRIERNKKKFVTAVIGLEAFDLELKKVAKDLGKKFATGASVTKDEIVVQGDVSIELEEFLLE Galma1 ICFFPLEYCEFGSSTRCKEWLKEEREDLYDKYSQVTIRRIERTKRKHVTAIHGLEAFSIDLKKAAKQLAGRFATGASVTKDEIVVQGDVSDEILEILEK Ganpr1 ICSYPPELCEWGGSEKCKAWLRDSHPDTFEKLQRVVIELSARSKRKHVTSITGLENYDVDLKKAAKMFATKFACGASVTKDEIVVQGEFADEISELIQT Gloin1 VCSLPPEYCEYGPTSKCKEWLQEKHSELFDKLSKVTITRIARNKKKSVTNVGGLQNFDIDLKKAAKNFASKFACGSSVVKDEIVVQGDVSDDLYDYILE Hisca1 VCSLPPEYCEFGGIKKCEEWLKDNHPDLHERLAKIQIRRVERNKRKYVTIVSGLEAHGLDIKKIAKELGKKFATGSSVTKEEITVQGDVSEEILEWLVS Klula1 VCDFPAEYCEFSGKKRCKAWLQENHPELYTKWSKVVIRREARTKRKCMIAISGLEVFEIDMKKLSKTFASKFATGCSISKEEVIVQGDLADEVEAYIHS Lacbi2 VCTFPPEYCEFGSSTRCKEWLKEEHPDLFDKYSQVIIKRIERTKRKHVTSIYGLDAFGIDLKKAAKQFASKFATGASVTKDEVVVQGDVSDEVLEMIEQ Lenti61 VCTFPVEYCEFGSSTRCKEWLQKANVELYNKFSQVTIKRIERNKRKHVTAIHGLEAFDVDLKKAAKFFAQKFATGASVTKDEIVVQGDVSGDIVEMIED Malgl1 VCTFPYEYCEYGSSSKCKANLEARDPTLYAQLSKVILSRVSRTKRKVITCVHGLHQFSPALKVIAKGLSSSFATGASVTQDEIHIQGDVVDDLRTMLIE Mellp23 ICSFPIEYCEFGTRSKCKTWLSETNPIQYKLLSKVTVKTVERTKRKRITTVHGLEAFGVDLKKLAKLFASKFATGASVTKDEIVIQGDVSDEVLDLFEE Mnele VCSLPPEYCEHGPLDKCKEWMEENLPDEYARLKQVVVGRSMRARKKYVTLVRGLKTCDMNLKKCSKAFGQKFACGSSVTGDEITVQGDVVDDMMDFIVE Monbr ICTMPYEYCEFSATKKCLSALTEKNMNLFIKLKKIIVTRSTRNKKKFVTSITGLKAYGLNLKQVSKAMSGRFAASSSVMGDEVLVQGDLTDDIEDFIAD Morel2 FCSLPPEYCEFGPTEKCKHWLSKNDKVLYAILSKVLIKRIERTKRKCVTSVFGLENFDVDLKKAAKLFANKFACGSSVTKDEIVVQGDVSDEIFDLILE Mucci2 -------YCEFSGTEKCKLWLKEKDEDMYEEVSRVLIKRIERTKRKCITTIYGLDIFGVDLKKAAKMFANRFACGSSVAKDEIVVQGDFSDELLKMI-- Mydma ICGLPPEYCEFGSEEKCKDWLKENIPDLFDDLKKVILKRETRSKKKCVTIISGLATFSIDPKKAAKVFANKFSCGSSVTGDEIVIQGDVADDLIDFLQE Neucr2 VCSLPPEYCEYGGTKKCQQWLEKNQPTMYSRISVVTIKRIERNKRKYVTSVSGLEAFGLELKKVAKDFGKKFATGSSVTKEEIVVQGDVSGEIEEFILE Orpsp11 --------------------------------SKITIKRCERTKRKHQIIVTGLDQYEIELKKAAKLFSSRFACGSSVTKEEIVVQGDVQDEIKELILK Pench1 VCTLPPEYCEFGGTKKCEEWLKENESDLWDKLSKILIKRVERNKRKFVTVVIGLEVFGLENKKIAKDLGKKFATGSSVTREEITVQGDVSDDLREWLLE Phybl2 ICTMPPEYCEFSGTEKCKEWLKDNHEDVYVSLSRVTIKRVERTKRKCVTTIYGLDVFGVDMKKAAKMFANKFACGSSVAKDEIVVQGDFSEELNDLILA Picst3 VCSFPPEYCEFGVSKRCKDWLQDNNQELFDKISKVLIKRIERNRRKHIISISGLEVFNIDMKKLAKTFASKFATGASVTKEEILVQGDVSDEAKEYIEK Plicr1 ICTFPPEYCEFGSHTRCKEWLHEEHPDLYDQYIQVTIKRIERNKRKHITAIHGLEAFDIDLKKAAKQFAQKFATGASVTKDEIVVQGDVSDEIVDMLEA Polpo FCGFPTEYCEFGPSAAC---LAENGP------PTITIELTQRTKRKHVTTIAGLEGFGIKLSDAAKLMAKKFSCGCSVVKEEIDIQGDFQEEAVDFIVE Pucgr2 ICSFPPEYCEYGTSSKCKTWLSTHDQKRYEEINKVTVKTVERTKRKRITTIHGLDLFGVDLKKLAKLFASKFATGSSVTKDEIVIQGDVSDEVLDLFDS Punst1 ICTFPPEYCEFGSSTRCKEWLQSTHPELYDKYSQVTIKRIQRNKNKYVTTIHGLEAFEIDLKKAAKLFAQKFATGASVSKDEIVVQGDVSDDIQDLLVS Rhior3 ICTMPLEYCEFSGTEKCKLWLRENDEDKYSEISRVIIKRNERNKRKCVTTIYGLDIFGVDLKKAAKMFANRFACGSSVAKDEIVVQGDFSDELHNLILS Rhoto1 VCHFPPEYCEFQPKAKCKAWLEENHPDLHAKYSKIVVKRIERNKKKWVTTVNGLHHFGVDLKKAAKLLANKFGAGATVSKEEILVQGDVSTEVEEMMLD Rozal11 DCTMPLEYCEFSGSPKCKNILQKENPQKFAELDKVLFKVEQRSFKKNVTVISNLEKFGIDLKKAAKRFANRFACGSTVAKEEIVVQGDVGDNLETFLMK Sacce1 ICSYPPEYCEFSGKKRCKVWLSENHADLYAKLSKVIIKREARTKRKFIVAISGLEVFDIDMKKLAKTFASRFATGCSVSKEEVVIQGDVMDEVETYIHS Salro VCTMPYEYCEFSNTKQCYTRLKEDDPDLFAELSAIVVTRIQRTKKKFASNIAGLKAFGIDLKKASKAISGRFAASSSVVGDEVQVTGDVTVDIVDFLTS Schco3 VCSFPVEYCEFGSSTRCKEWLKEAHPDQFDKYSQIIIKRIERNKRKHITSINGLEAFGVDLKKVAKQLASKFATGASVTKDEIVVQGDVSDEILEMIED Schpo1 VCTLPVEYCEFEGTKKCKEWLKSSHPDVYDKLSKVLIKTIERTKRKRVTTVQGLDAFGIETKKAAKMLANKFATGASVTKDEIVVQGDLNYDIFDFILE Sorma ------EYCEYGGTKKCQQWLEKNQPAMYSRISVVTIKRIERNKRKYVTSVSGLEAFGLELKKVAKDFGKKFATGSSVTKEEIVVQGDVSGEIEEFILE Sphar VCSVPPEYCGFGPTKACKEALQSKNEDLYDELRAITLLRRNRGGRKYITVVVGLKTYDIDLKKAGKVLGSKFACGSSVTGDEITLQGDVAADLEEFLPE Spipu1 VCSMPVEYCEFSGTATCKKWLRKEHPTEFARIQKVIIRRVERTKRKCVIEVSGLENFGVDLKKAAKLFATKFACGSSVTKDEIVVQGDMQDAIYELILK Sporo1 VCSFPPEYCEFSSKSKCKQWLQETHPSLYSKYSKVTIKRMERNKKKHVTSVHGLHLFGVDLKKASKLFANKFGAGATVSKEEILIQGDVSYDVEEMILD Stehi1 VCTFPPEYCEFGSSTRCKEWLESEHPDLYQKYSQVQIKRIERNKRKYVTAVHGLEAFDVDLKKASKLFAQRFATGASVTKDEIVVQGDVSQEIYDMIEE Tapde11 VCSLPPEYCEFQPTAKCKEWLEAHHDDLFQKLSKVLIKRIERTKRKYVTGVFGLEVFGIDLKAAAKKFANKFATGASVSKDEIIVQGDVSDEIFDFITE Thetr --------------------------------------------------------------------------------------------------- Treme1 ICTLPTEYCEFGPSSKCKAWLEKEDPAEYSRLAKITIKRSERTRRKHQTHIHGLEAFGVDLKKAAKLFAGKFATGSSVSKEEIVIQGDVGDDIVEMLQA Trire2 VCTLPPEYCEYGGTKKCQEWLEKNQPAMYERISVVTIKRIERNKKKFVTAVIGLEAFGLDLKKVAKDFGKKFATGSSVTKEEIVVQGDVSDELEEFILE Umbra1 VCSMPPEFCEFSGTGKCKAWLQKNNAKEFARLSHVIIKRVERTKRKCVTTIHGLEVFDVELKKAAKMFANRFACGSSVAKDEIVVQGDFSDELLDLILA Ustma22 VCTFPPEYCEFGPSSKCRNWLHEHQPELYAKLSRIVLKKEARTKRKVTTSIVGLHLFSPALKVVAKALSSRFATGASVSKDEIVVQGDVADDVRDLILS Walse1 ICQFPVEYCEFSNSKRCKQWLEEELPEVYISLSKITIIREERTKRKVTTHIQNLDAFSVELKPAAKLFAQKFATGASVTKDEIVVQGDVTDEVEDMLHA Zygro1 VCSFPPEYCEFSGKKRCKIWLQENHAELFEKLSKIIIKREARTKRKSVVAISGLEVFEIDMKKLAKTFASKFATGCSVSKEEIVIQGDVMGEVENYLHS [Cluster2205.fasta_al_trimmed; alignment length = 167] Allma1 DDDDDNIVD-VEFDFFSLVE-TDYHAVKFLTQ-ALSGLVDLTDHLL--VGSTVK-EASD--PYAVTTLVGLTKPLAAFL-SKGALLEVAWLVHERLINVPWQVAAPLHRLLVDEIKDA--DSKD--YEFEYAVVLCTYLEQEYMEKHARKALVISKLPKIV-EELEE Ashgo11 QDADGEIIN-IDFDFFNGNPGVDFHALKLLRQ-LFMQLSTLADIILQS--TTIKTQESD--PYCFLSFVDYAKYLVNL----ATIDNCALILCERLINMPVEVVPPLYNITLNDVSSNSSDGKH--FDF--YLVVSFHEEDRHMEKYA--YMVLEGLVRSI-GDLEQ Aspfu1 -----DIVN-VDFEWFDPQPAVDFHGLKLLRQ-LFFDLSALTDLILAQLGSTVKVNESD--PYAFLTVLNLIKDLTSYLQRKSQLLSIGLILTERLINMPAEVVPPMYSMLLEEIAWAIEDKEP--YNFSHYLIVSFHPEDEVFERHAGSLILIPKLEAAV-KDVTD Aurde31 DSDDEGIVQ-VDFEFFDPNAN-DYHALKLLNQ-LFLAVEALADLLVAQVGTTVKTKDSD--PYAFLSVVNLVKALRSYISSKAPLLQVGLVVSERLINMPVQVVPPMYRMLLDEIQWAIDDNEP--YTFSHFIFLSFHFEDEVIAKYAGRLMLLAKLPAIV-EEMAR Batde5 -----ETVD-VDFDFNDPKE-IDFHGIKLLQQ-TFVDVSAFSDLIISQVGSTVKA-NVD--PYALLTAINMVQHLREYLLEKERLFSLAIVFNERLINMPPQISLPMFKMLAEELEWAQDEDQP--FKFSHLIFISFQPEDELIEKYARRILVVSKFCNII------ Botbo1 EDSGSEIID-VDFEFFDP-AEIDYHAIKLLRQ-LFLHLSELTDLILSQLGTTIKTKDSD--PYAFLTVLNMIKALASYFLEKQRLLSVGLILSERLVNMPTEVVPPMYKMLGDEITWANDENEP--YQFEHYIVISFHPEDACIKKVAGRLMVFSRFQELV-TDMSA Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel DDEEENIMD-FDFEAYPPSE-DDRDGIVMLTQTFLIDLKAMSEGIIAKHGVVLTQTEEDYMAYGLCTTVPLIKDLFTYVLNRQ--VSSALFVNERLLNFPTIVVPQIFGSIREDLS----------FETKYKTIIYVHMDVEPGSKFHRRLVIMKRFDAFL-KKGSD Canalb1 ESTQQETVD-VDFDFFDLNPQIDFHATKFLRQ-LFFNLSEIADLILREVGTSIKTMESD--PFAILSVINLIKQLIEYILNKKKLLTTGLIISERFINMPVEVIPPMYKMLLQEMEKAEDAHEN--YEFDYFLIISFHLEDQILESNTLSLILIDNLAKSV-IEMEQ Cangl NAGDEEIVN-IDFDFFDGNPDVDFHAVKLIRQ-LLVQLSALSDLILSS--TTIKTKESD--PYCFLSFINYAKYLRKL----QTLDNCALVMSERLINMPPEVVTPLYRITMEDAAAA-NEGKP--FDF--YVIVSFHEEDRFFEKHA--YIIIDSLVKSI-NEFEQ Capow DGADEEEIQ-VEFDAVGPEE-ADFFGIKILEHWFL--TSEIADTVVAQIGSVIKV-YGE--IYGVMSVINMIKQIRHYVLSKLAPILVGLIINERFINIPFQLAPPLHASLHQQIKLALEDGEA--FDFSHYLFVMVNPEDEIFVKHA---KLFVAL--LT-REQAE Catan2 DSDREEIIP-VNFDFFGLVD-TDFHAVKFLTN-ALSGLVDLTDLIL--FGSGVK-ENSD--PYAVNSVVGLVGPLRDFI-LSTALLEAALLLHERLINMPWQIGAPLFRLLMEELQEAADDEKQ--YKFDYLIALCAFLELEYLEQFARRGIVFSKLPELV-ATLEK Cioin SSSDEEKVD-VDFEGFPLSD-SDFDGIRLLTQ-LLINLSKLTESLIGQVGTVLKQEEDE--VFALVTCLPIQKSIVKHFISKTKILQTGFLINERFINVPSQAALPMFEKLFSELESAKNSNHKANYNFTHYVIICMNAEEEIFAEESRRVLLLKNFERSF-EKLKS CocheC53 SGSDEDIVN-VDFEWFDPQPAVDFHGLKLLRQ-LLFNLSELADLILSQLGSTVKVNETD--PYAFLTVLNLISDLTSYLSKK--LLAVGLILTERFINMPHEVVPPMYTMLLEEIQWAVEEKEP--YTFTHYLVLSFHPEDEVLHKHAGHMVLIDKFKGAV-EAVKT Coere1 TGSDSGMVN-IDFEFFDPAT-EDFHAMKMLSS-AFFNVSELVELILEQIGSTVKL--GD--PYGFMSVVDMIKQIRRYLEKKREILDTGLLINERVINMPPQVVAPMLRMLAEETRRATDAGEP--FDFEYFMLLSAHAEDEFVEEFARRCLVIANFAPLI-ERLDK Conco1 QQNDQETID-VNFEFFDPKQ-EDYSTIKFLNA-LFINNGDLSDLIISQIGTTIKTADED--AYSIFTILNMIFQLTNILLNGRSLLALGYLVNERLINMPVQTAPPMYTMLQEEIQWALEDKEP--YNFEYFFLLSFNAEEELLQPLARKLLVFNKYQEIL-RVLDQ Conpu1 DGNESSLID-VDFDFFGPNPDVDYHAINLLNQ-LFIHAHQLTELILSQIGSTIKTEEAD--PYALLTVLNMIKAIADYALSKKGLLAVGLIVCERLINMPVQVIPPMYRMLIDELKTAIDANEP--FAFTHLLFISFHLEDEQIQQAAGRMMLVDRLQALV-DTMSE Copci EDSSSSLVD-VSFDFFSPNSSVDYQAIKLLQQ-LFFNLHELTELILEQIGSTIKTEESD--PYALLTVLNMMKALAQYCLSKQSLFSIGLVICERLINMPVEVVPPLYNMLRDEVRNSIAANLP--FKFSHLLFISFHAEDALLSSLGGRMILVDAWDVIA-EQMMK Croqu1 GSDTEETID-VTFEFCDLNP-IDYHALKLISQ-LLIDVGELTDILLSEIGGTVKCESSD--PYAFASVLDMVSSLTSYLLSSLATLNVGLLLSERLINMPVQVMPQLLSQIGSEIRHAQSKNAP-GFAYDKLLIPSYHPEDHIISQFAGRLMLISKWDQMI-LNLMT CryneH991 SESGSSMIN-VDFDFYNLNPEVDLIAVKLLRQ-TLIDVHPLAELLLAEAGSSIKTEESD--PWGLVAVIDILKPFLDYLGSTQSVFNPALVFSLRMLNLPLPLIPHLYRMLLEEL-ETKEEGR-----FTHFLVWGYHPEEEFMDKVAGRLVLLSKLVNAI-QSMQA Crypa2 SD-DEDIVN-VDFEWFNFDTEIDFHGVKLLRQ-LFLDMSGLTDLMLQQIGSTVKVKAND--AYAFLTALNLVADLVGYLSGKVPKVLVGLVLGERLINMPPEISPPMYSMLVDEIEAAVEDKEP--YDFTHYLVVSFHPEDEILQKHAGYMTLIAKFPAAV-KAVVE Debha1 E--DEDIIN-VDFDYFDLNPDVDFHAIKFLRQ-LFFDVSSLADLILTKVGTTIKTMESD--PFAILSVINMLKTVVDYVLQKRKLLEVGLIISERMINMPVEVVPPMYKMLLEEMTKAEDAHEK--YEFDYFLVISFHYEDMVLEENALSLILINKLAESI-PQMEE Dekbr2 E--DEELID-VDFDFFNINPKIDHEGTKFIRQ-IFISFSQLTDVLLSKVGSTVKTPNGD--VFSIITVTGLLKKLSNYLIQKHQLLVLGLLFSERMINMPVETVPPMYNMLIKEMEKAE-------YKYDYFIIPSYHDEDVILEKYALSLILINSLEKAI-EEMNS Dicdi DDSDDDEIQ-ADFDIVPSVD-KDYHSIKMIVR-LVFNAGELTDLIIEQFGRSINI-SED--PYGFISILNYIQGYIDYINEKSKLLNLGLIFSERFINIPNQLAHPIYQFMQFDVELMQEKNNDKNYDFKNYLVFTQKCEDKYFREYAGLIMIISKYQQFL-NDLKE Dmel EPHPDEEVQ-IDFEGRAPVD-PDAQGISLLQR-LFINCNQMADLIIAQIGSVICQEDGT--IFGITSVLNLIAQLRTYILDRKEILDVGFLINERFINIPAQISVPLLQSLQQEIEAAKAKKMK--YDFGTLLLLVTNAEDELLSDRARKLLVLKKLPQLI-DDIQR Enthi DAMEE--IN-VDIFLENQSE-NDYLEIKFLLHSPLINLRTLTD-ILIKIGSVIKN------TYGLAIPVDFYDDFCKYTINAQKVLSRMLIVNERMVNCPSDLNSLLHNTIYEEIG----------YDTEHHITQPLLMENQIYSKFAISIMIIKQISNIL-KEITD Falba DNNEEEIVQ-VDFEFFNLLD-ADPASIRLLSQ-VL--LFGLAEHICAVTGSCIR--NPE--PYACLALVNLLAQLRDYLAGRRASLQSALVVNERLINMPAQTAVPMFRMLADEVEAARRDTSS--YSVDRLVFVLVNEEEEIVLEAV---AVLDRLRPLV-RKIEE Fomme1 GGSDSSLVN-VDFEFFDPNPNVDYPALKLLSQ-LFFSLNELADLILSQLGTTVKTIESD--PYAYLSVLNMIKALRSYILQKQSLFDVGFIFSERLINMPVQVVPPMYRMLADEIRMANEDAEP--YKFTHYLILTFHPEDGYIQKYSSRMMLVENFQPMV-DEMCS Fusgr1 SD-DEDMVN-VDFEWFNFDPEVDFHGTKLLRQ-LFFNMSALADLVLSQIGSTIKVKAND--AYALLTVLNTMKDIIKYLVEKADVLSVGLVFSERLINMPSELAPPLYSMLVDEVEAAVEDKEP--YNFSHYLILSFHMEDEVLHKHAGHMILISKFPGAV-KSVNE Galma1 ---TSSLVD-VSFEFFDPNPNVDYHAIKLLTQ-LFLYVHELTELVLSQVGTTIKTIESD--PYALFTVLNMIKAIANYLLSVKALFSVGLVLCERLINMPVQVVPPMYNMLADEVKWANADGEP--YQFTHLVFISYHPEDDILLKPAGRVVLV------------- Ganpr1 ----------------------DFHGLKLFRQ-LLTFFSDLADHVLERIGCVVKVEDPD--PYAIVTAVGLLAHLRSYITGKAQLLEVAFLFSSRLVNMPPEIAPPMHKSLLADCAHAVSVGEKE-YDFGYAVYICFHPEDDTLAKNAGRVMLVKGWEAAV-RDMEK Gloin1 GHSEEELVD-VDFDFFDPKE-IDFHTIKLMIQ-LFFNLSELSELIINQLGTTVKVTDSD--PYALLTVLNMIKQIKNYLIEKVELLKIGLILSERLINMPVQIVPPMYKMLQEEIQWAIEDNEP--YEFEWYLIITFHPEDEIIEQIAMKIFLLSKLDKLI-NDLEV Hisca1 SSSDEGIVN-VDFEWFDPQPAVDFHGLRLLRQ-LLFDLSALTDLILSQLGSTVKVNEGD--PFAFLTVLNLIQDLTSYLQRKDNLLSIGLILTERLINIPAEVVSPMYTMLLEEIAWALEENEP--YNFTHYLILSFHAEDELLQKHAGHLILIARFEAAV-TDLKE Klula1 ENGQEEIIN-IDFDFFNGNPDVDFHALKLMRQ-LFIQLSELANLILDS--TTIKTKESD--PYCFLSFIDYAKYLRKV----QTIDQCSLVLSERLINMPPEVVPPLYTITLEDVKLALGDDKN--YDF--YLIVSFHEEDRFLEKLA--YMVLAGLIKSI-EDLDA Lacbi2 SSSSSSLIN-VSFDFFNPNPKIDYHALTLLSQ-LFLKVREIVELVLGQVGTTVKTEEGD--PYALLSVLNLVQAVVEYVLGKKRLLMVGLVICERLVNMPVQVVPPMYRMLVDEIDAALRDGEP--YRFSHLLFISFHPEDDLISQVSGRMMLVGALRRLV-DRMGE Lenti61 DESDSSLVD-VDFEFFDPNADIDFLALKLLTQ-LFFLLHDLADLILAQVGTTVKCRESD--PYAFLTVLNLIKALISYILEKQALLGVGFIFSERLINMPVQIVPHMYRMLADEIQWALDDNEP--YDFKYFIIISFHPEDEYIRKFAGRMMLVTRLRDLA-TALVE Malgl1 -----------------------------------------------------------------MSCVTLAKLVQDYFKSQ---LSILFILHERMINLPPQVMPPLLRMLLAEVEETLAETSA--PAPTHALFFSFHPEDEFIREAA---LAVTKMPAVL-ERL-- Mellp23 DSDTEETID-VTFEFCDLNP-IDYHALKLISQ-LFIDIGELTDILLGDVGGTVKCESSD--PYSFASVLDLVSALTSYLMSSMKTIEVGLLLSERLINMPVQVMPQLLAQIGNEIKHAQSKNAP-GFNYSQLLVPSYHPEDHIISQFAGRLMLISKWDQMI-LSLMT Mnele -----ELTQVVEFEAFPPAD-EDWSGVRLLDS-LFLDVGYFSQTLIDNVGTVIKGEDDP--VFAVASLLPLFEQLSSSLLAKEKILNSAFLINAKFSNLPLQITAQLYKALKMELITERKENPE--YNVKNLIVFG--------------------------N---- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 GSDGEDIIN-VDFEFFDPKE-MDFHAIKLLNQ-YFFALSELSDLIVAQVGTTIKVVESD--PYSLLTVLNMMTQIRDYVFTKKELLAVGLILSERFINMPVETAPPMWRMLLEEVKWAVDEGLP--FNFEYYLLMAFHPEEEMLQQFARRMMLITKIPEVV-QLMTN Mucci2 DDGLQDIVD-VDFDFYNPDD-IDYHALKLLTQ-LFLNLGDFADIMIEEVGTTVKVQKSD--PYAILSIINLVKQLCSYLANKKQILSVGWVVSERFINMPVEIMAPMYTMLTDELKNAVKEKEP--YVFEWYMFISFQSEDEIIAKYARKLLLVSKFNDMV-NEITK Mydma DSNDEEDIN-VEFEAEMPFE-EDFHGIKLLLN-VFVDISELCELIINQVGSTMKIKDSE--VYGIFTVLSFIQQLQKELVSKAEMF-VAYVINERFINLPGQIAVPFHKSLIREVEEAKKEDST--FELDYLLLISTNFEDEVFFKASRTVIVVKNWNKIV-KDIAE Neucr2 SDSDEDIIN-VDFELFNYDKDIDFHGVKLLRQ-LFFDLSGLSDMIIEQIGSTCKVKAND--AYAFLTVLNAVAQLIEYLSDKPELFTVGIVLSERLINMPAEVIPPMWNMMIEEIQDAVDDKEP--YEFTHYLVVSFHPEDEEMRKHAGFMMLIGRFKQAV-KAIGD Orpsp11 ENEDEEIID-VDFEFFDPQP-QDFYGYKLLKQ-IFINLSDLADLVLSQLGSSVKVKKED--PYAMLSVLNMIQQIKKYLNDRNGYLNVGLLLNERLINMPPQVVPPMFRMLLEEIQWAIDDKEP--YEFAYYMIISFQPEDEIIEKYSRRVLIFDKLQNIT-DEISE Pench1 SDSDEDLVN-VDFEWFDPQP-IDFHGLKLLRQ-LFFDMSALADLILSQLGSTVKVHESD--PYAFLTVLNLVQDLINYLKTKSELLSIGLILTERLINMPSEIVPPMYNMLQEEIAWAIEDKEP--YTFSHYLVLSFHPEDEVVERHAGSLILIAQFEPMV-KALTQ Phybl2 -----DIVN-VDFDFFNPEP-VDFHALKLLGQ-LFINLSDIVDIIIEEVGTTVKVQESD--PYAILSVINLVKSLCSYLLAKTDILSVGWIVSERFINMPVEIMPPMYSMLQQELKQAVEKKEP--YDFEWYMIISFQAEDEIIAKYARKLLLVSKFDELV-GDIEA Picst3 -----ELVN-VDFDFFDLNPEVDFHATKFLRQ-LFFDILGLANLVLAEVGTTIKTKESD--PFALLSVINLIKKVTDYILKKKKLFQVGLIVSERMINMPVEVVPPMYKMLVEEMAKADDAHEK--YEFDYFLIISFHYEDMVLEQNSLSLMLLDKLAACV-PLMEE Plicr1 SDSDSSLID-VDFDYFDPSPTTDCAALKMLIQ-LFLGAHPLAELVLQEASTTIKTIESD--PYAFISVLDLIKALVSHLRSKA----PAWIFSERLINMPVQVMPPMYNMLLDELSAAQQSH-------THYLFISFHPEDEVIMKHAGRIMLVDKLRDIV-KEVGE Polpo DDDDDNEIN-VEFDISTVQD-NDYHSIKMMTK-LVFSAGEITDLILEQFGRAIRV-NDD--PYGFASVLNHIQGYTEYLELKGDLLSLGLFFSERFLNIPPQLVQPLHQFLHWDLELLVESKINE-FKFNNYLFLT---KDEYLRQYAGLIMIVSNIQSFL-NTIKE Pucgr2 AGAENEKIE-VTFEFCDLNP-IDYHAIKLISQ-LFLDVGELADLVLSDVGCTVKCEDPD--PYAFISVLDLILTLTNYLTSALKVLKIGLVLSERLINVPVYIMPQLFTQLGNEIKHAQSKNAP-GFKFDRLLIPSYHPEDQIISQFAGRLMLISKWDQMV-AALKE Punst1 DGDDSSLVD-VDFEFFDPNPKVDYIALKLIVQ-QFLQVNDLADLILSQVGTTIKCIESD--PYAVLTVLNMIRAIRDYALAKQGLLGVGLVFSERLINMPVQTVPPMYRMLENEIKWAIDDNEP--YRFTHLMFISFHPEDEIIQKFAGRMMLVDRFQELI-AAINR Rhior3 DDGLQEIVD-VDFDFYNPDE-IDFHALKLLTQ-LFINLGDLADILIEEVGTTVKVQQSD--PYAILSIINL----------KESILKVGWVVSERFINMPVEVMPPMYAMLQEETKKAVQQNEP--YSFEWYMFISFQSEDEIIAKYARKLLLVSKFDGLV-DEISK Rhoto1 GEGGSEMLD-VNFSFFDPQPQ-DYHSIKLLSQ-LLLDLGGVTDIVLEQVGSTVKTHEGD--PYAVLTVLNLLSSLVSYILSKSSLLSVGLVLSERMVNMPPQIVPPMYRMLSEELQWAKDDGEP--YHFSHLLFVSYHVEDEFIQKFAGQLMLVPKFSDIV-DGL-E Rozal11 SVSSESNVI-VDFDFNNPEE-KDYHPVKLLTL-QFPNLSNMADIIVEQIGTCINV-------MAINTIIDL-----------SQCFN---------------------------------------NKFDYYILISVNAEEEFLLPFSRCIMLFDRIRKVLVQKIGP Sacce1 EEQNGEIVN-IDFDFFGGNPEVDFHALKLLRQ-LFIQLSSLADLILGS--TTIKTKESD--PYCFLSFVDFVKYLQKV----KTMIDCALVLSERLINMPPEVVPPLYKITLEDVATALGDDKH--YDF--YIIVTFHEEDRFFEKYA--YMILEGLVKSI-DELET Salro NEDDDQALQ-CDVRACCPGE-EDFWGIKLLHQ-LMFVYGDLADSLIENCSTVIKPDKYD--VFAIAGVIPLQASLTKWLAKKADVVSTAFVICERIINLPPQLATAMYDTLLNDMLALPKADRP-----KQVVMMFYGPEDTFFFKSAYRVVCVKAFRAAA-QQVAS Schco3 RGSDSSLVD-VDFDFCSPNPDIDYHALKLLVQ-LFFHLEALTNLILSQIGTTVKTEEGD--PYAVLTAISVIKALTEYWVQKQRLLDVGLVLCERLINMPVQVIPHMYRMLAEELKAAVEGGQP--FNFTHLLIPSFHPEDEVIREAAGRLMLVERFVEMV-RKMGE Schpo1 SESLKDFIN-VDFEFFDPQP-IDFHAFKLLKQ-LLVNLSALADLILSQLGSTVKVNNSD--PYAMLSVINLIKQLTSYIISRQKLLEVGLIVNERLINMPVQVIPPMYNMLLEEMQWAINENEP--YNFTHYLLLSFHPEDEQFREVAGELLLMEDFKNLV-PKLME Sorma SDSDEDIIN-VDFELFNYDKDIDFHGVKLLRQ-LFFDLSGLSDMIIEQIGSTCKVKAND--AYAFLTVLNAVAQLIEYLSDKPELFTVGIVLSERLINMPAEVIPPMWNMMIEEIADAVDDKEP--YEFTHYLVVSFHPEDEEMRKHAGFMMLIGKFKTAV-KAIAD Sphar SSSSKEVMD-FNFEVNSIKE-QDFHGIKLLKQ-LFVHLSELADIIVSQVGSTITI-------YGIISVINIIQELKKYMLKKQALFTLGLIVHERFINIPAQLASPMYTALFDEVDSAAHDGEP--FKFDNYLFMAINVEDVLFEKEARHVMVLAKVALVM-ERMPI Spipu1 ASGEEDTVD-VDFEFFDPKP-IDFHGLKLLRQ-TFINISSLADIIISQVGSTVKV-EQD--PYALMTVINLVKEIKGWLLDKVQIV-AGLIFNERLINMPPQIVPPMLKMLLEEMEWAVEDGEP--FRFEYYIYISFQPEDEIIQEHARRVFVIEKMKAVL-EQFES Sporo1 ----EQMLD-VSFSFFDPQPQ-DYHSIKLLSQ-LFLDLGGVTDLVLEQVGSTVKTSQGD--PYAVLTVLNLISQLVKYLLSKSTLLAVGIVLNERLVNMPVQVVPPMFKMLQEELQWAIEDAKP--YHFSHYLFLS------------------------------- Stehi1 EGNDSSLID-VDFEFFDPNPSVDYHALNLIIQ-LFFHPHDLAELILSQVGTTVKTKESD--PYAFLTVLNMIKALIAYALLKQNLLGVGFIFSERLINMPVQVVPHMYRMLADEIKWAVADNEP--YAFTHYLIISFHHEDEQIAKYAGRMMLIEKLPELI-NTMSE Tapde11 EDEDESMIN-VDFEFFDLNKKVDFHALNLLKQ-LLFELGAIADLILEKIGSTVKVEESD--PYAVLTAINLLKKLVDYFLSKNKLLATAFLFSERLINMPVEVSPPLYRILSEELTAKSAPEDD--FTFDNYVVLSFHAEDEILIKYAGELLILAQLGSAV-LEMQD Thetr SGSDSDIVD-VDFDFCDPSA-GDFWAVKSLAH---YDAGSVADLVCAQIGSVVKA---Q--VVGYISAVNLLESIKAYLKRK-----AGLILNYRLPNAPDQLATPLHASLFQELAEVSLEEPE--FGFDNYILLTFYVEEELYFKHAGHILIIDAIGALV-AEMDA Treme1 DESDSSMVN-VDFDFYNLNPDVDQITVKFLRQ-TLIDVHPLATLILEEVGSSIKTEESD--PWGLLAAVDILSSLLTYFTSTRIFFDPFLLFSLRMLNLPLPLIPPLYTMLLSELTEAEESGRI--PKITHFLLWGYHPEEEFIDKVAGRLILVDNLARAV-KAMTD Trire2 SD-DEDMVN-VEFEWFNFDPEIDFHGTKLLRQ-LFFNMSALSDLVLSQIGSTVKVKAND--AYAMLTVLNTMKDILKYLVDKAELLGVGLVLSERLINMPSEIAPPLYTMLVEEVEDALEDKEP--YDFSYYLILSFHPEDEVLEKYAGHMILISKFKEAV-KAVGD Umbra1 QDEDEEIVD-VDFDFFDVDP-VDFHAVKLLGQ-LFLNLTDFSDLIISQVGSTVKVKESD--PYALLTVINTVKGVVEYLMSKAQVLQAAIVISERFLNMPVQIMPPMYKMLMEEMAKTNAANGG--FDFEWYVFISFQSEDEIIAEHARRVMMVSKMKAMI-EALEE Ustma22 DGSEEDFIN-VDFDFRAPEE-IDFQALKFYTH-NT--LSSLADHVVKTVGTTIKIEDQD--PYAFVSAITLANSLSKYL-LESAASSVIAVLHERMVNMPPQVAPPLYKMLLEEVQASLVSTSA--TRPSHYLFFSFHPEDIAISKFA---ALVDKMDALL-QQIET Walse1 VEDDEEIVN-VDFDFFNIDE-IDYHAVKLLVQ-LFLELHTLTDLILSQVGTTIKVKESD--PYAFLTAVNLVSNLSNYLLNRNQLLSVGLLLGERLVNMPVVLMPHMLRFLLEELESASKSGQA--YNFTHYLIPAFHPEDDITQDFTGRLILIEKLKNLVLPKMIE Zygro1 EEQVNEVVN-IDFDFFGGNPQVDFHAIKLLRQ-ILVQLSQLSDLILAS--TTIKTPESD--PYCFLSFVDYARYLRR-----RTVESCALLLGERLINMPTEVVPPLYKITLEDVTNALGDGKH--YDF--YVILSFHVEDRIFEKNA--YIVLQDLLKSI-SELEH [Cluster2216.fasta_al_trimmed; alignment length = 465] Allma1 -----------------------------------------------------------------------------MGLVAIAHQ---------------------------------------------------------------------FRFSLELP----------AA-TSAHAP------------------------------------------------------------------------ATMVVL------WFAVMLAQPHKEERFLSPIYPAVALLAAQGVAAMA------------HRARTM--LLVIVALGALRSLALYGAPLQLDWNR-MCLGNDWFLAPGHWVLPRIEFVQ--HGFEGQLPAHFAPSGTATC--FNDANRM--EVS-RF-VDLDQ-CDFILGRD--------AIFAAGSNAVVGMCANMLYRVVYHPVWQQYCLY Ashgo11 ----------------ALAVLRLQPLYSLISDCDETFNYWEPLNLL-KQTWEYSPEYSIRSWAFLMPLFYAGR--AALGLLSLVFEKNLYLELTNTEVAEMWLAFQLLNPGWFHASVELLPSSLAMVLLLGYLKDSLRPFVSALFLFLAGLLGWPFVLVLGLPLVLHYVLSVLVL-SMILGCV-FVVDSIFYRRL-TLVPWNIVKYNVLGTSGPHIFGTEPWYYYVFSLLLNLPLPTLIFAIVALLH-------------LWPVWCWLVVFIAQPHKEERFMYPIYAFVTLASSIGFTKVS--------KLLYRH----FKGAVFAVQSVLRITALYTAPLHVYSTLNVCTGREWYHFPASFFLPRLRFVN--SGFDGLLPGDFPEEVISQV-PMNQFNKF--DPG-KV-VSIDM-CDYYVDIMMQFDP----TDMPLGWEIS-TCAPFIDRAFQIPKHLQYCVF Aspfu1 --------TSQRTKPRVFLISNFAAALAPIQDCDEVFNFWEPAHYL-LQTWEYSPAYSIRSWLYVSAHFYTIR--FVLAAVCAACETRLYSAILNPRVGLLFLIIVAFSPGMFHASAAFLPSSFTMYTSMLGLASFLDKTAQGIMFGLGAIMGWPFAGALIIPLLLEEVAIIIRC-LAILGVE-IAVDYLFFQKF-AIVPWNIVAYNIFGGRGPDIFGTEPWTFYIKNLLLNFNI-WFVLAVSAAPILVLTNVQTLLRTVVTPFYMWLAIFTIQPHKEERFMYPAYPFIALNAAISFHMILSYV--------SNPKEIIMVMAVILMAGLLRTLGMYNAPLKVMEPLFVCFGKEWYRFPSSYFLPRAKFIK--SEFRGLLPGEFPEAGTSQI-PMNDRNEE--DLG-KY-VDISQ-CSYLVDSSFP-EPDY--VLDESEWETI-TCKGFLDRLIWVPSWGQYCLL Aurde31 IQTIRLRGSLQDQVRRLLLLMRVGAMYSNISDCDEVFNFWEPLHFA-FQTWELSPAYAIRSWAYILLHFFSLR--IAFAVASSFAEAKFYRAVINEHVGRYLLLMLLTSAGMWNASTAFLPSTFAMYTTMLATSYFVFRTLFATLFATGAVVGWPFSLLLAVPFVAEELLLLTA--ALVIVPV-FAIDTVAYNRF-VLTPLNIITYNIFGGRGPDLYGTEPASFYILNLLLNFNT-LALLALFSLPALAIVSSAYTMLAVLAPFYLWLGVLSAQAHKEERFMFPAYPLLCFNAAVTLYLLRGLVERTFINITASKTGLFFTSSVIVTISISRILALYHAPLSVAYHFSLCISKEWYRFPGHYLVPSVLFVK--SAFDGQLPRHFDEDVTRRV-PLNDLNKE--ELS-RY-VGALT-CDYLVDLDFPKEPRY--SVQSETWDRV-ACRPFLDRTLWLPQYGDYCLL Batde5 ----------------------------ILLDCDEVFNYWEPTHYL-LQTWEYAPQYAIRSWAYITFHFYLTR--LVFALASAYTEAQLYETIVHPRIARYTLVLLMASPGMFIASTAYLPSTFSMYTVTWAFALYLANTWILMAATTGAFWGWPFAGFMFIPFCLAMLFSVL-I-AVSTAPL-LVLDRFYYQKW-VFASLNIVLYNVFG-RGPDIYGTEPWYFYFLNGLLNFNL-AYVAALVCGPLLRI---------FLVFFYLWLAIFTIQSHKEERFMFVVFPIICFYAATTLYLYRGILEMLLM---GIRIVSIIVLQMCSILSALRIYAGYHAPIDVYTILNVCVGKEWYRFPSHYFLQRLRVLP--SAFKGLLPKYFKSDFAEFV--MNDLNRE--EVD-RY-WSVDQ-CDYIIDTSPQVEPIY--AMDTETWKRL-YCTPFLDRVLGLPVWLDYCLL Botbo1 TEGVRLRKPLQDQLRRIFMAIRVGAMYSIIQDCDEVYNFWEPLHYL-FQTWELSPTHAIRSWAYLLLHFFAVR--LTLAAVSSFCEAKFYRAVMNDRLGRYMLFMLVCSAGMWNAATAFISSSFTMYTTMLAFSYAFKRTRATVLFALGGILGWPFSLLIAVPFVLEEMFVLVA--STIFIPV-IGIDTLAYGKL-VIVPWNIVKYNIFGGRGPDLYGTSPWYYYIHNLILNFNL-VLPLALASLPTLALESSPFTLLTILAPLYLWLGMLSLQPHKEERFMYPVYPLLCFNAATTLYLVRGLMETAFVKATAGRTSIFTTLSVVLLISASRILALYHAPLDVAHHFRLCYGKEWHRFQGHYLVPTVDFIE--AGYDKGLPRHFDPSKTRMV-PLNDRNRE--EPS-HY-VDVNT-CDYLVELDEPYGQRY--AIDTEAWDRV-VCFPFLDRALWVPSFSDYCLL Botci1 ------PQPASHSKKKVFLGANIAALYAPIQDCDETFNYWEPTHYL-LQTWEYSPEYAIRSWLYVMLHFYFIR--YCLAFICALCQTQMFRVILNPRVAMFFMMANIFSPGFFHASASYLPSSFAMYTTMLGMAAFMNKTAQGIFFAVGGILGWPFSMALSAPFLIEEVIFVIDT-VMSKFSE-FVVSGFFYRQL-VIVPLNIVLYNIFSGRGPEIYGTEPWHFYIRNLILNFNI-WFVLAISALPLFILGGTTTALRSVMAPFYIWLAIFTFQPHKEERFMYPAYPCLALNAAMSLHIVLAAF--------SDPKTLVFVSFFIIGIGVARIYGIYSAPLKIYSPLSVCFAKEWYRFPSSYHLPKAKFVK--SEFDGLLPG----------------------------------------------------------------------------------- Caeel GSGPPQKPP---HKANMLLSIRIGAIWGIINDCDEVYNYWEPLHLF-FQTWEYSPVYAIRSYFYIYLHFTLIR--LTIGLFCLLGEYYAFDAIINIATGRFFILFSIFSSGMFLASTAFVPSSFCMAITFYILGAYLNNWTAGIFVAFSTMVGWPFSAVLGLPIVADMLLLLVIG-LCIGGVQ-VITDSHYFGKT-VLAPLNIFLYNVVSGPGPSLYGEEPLSFYIKNLFNNWNI-VIFAAPFGFPLSLA-------VALFAPIILWLLIFGSQAHKEERFLFPIYPFIAFFAALALDATNRLC---------------LSILFILCLSASRTYSIYGSHVEIYRSLRVCVGKEWHRFPSSFFIPEMRFIQ--SEFRGLLPKPFLKSVTRHI-PMNNLNQE--EIS-RY-VDLDS-CDYVVDVDMPREPDF--RKMEDNWKPV-DSLPFIDRAFYVPNVMTTCTL Canalb1 ----------------LNLLYRLSGLYMIIADCDETFNYWEPLNLL-KQTWEYSPEYKIRSYAYLIPYFFIIRTLGIVGFTCYC-EWKLFCSL-SASIANWFLLLNTIAPGMSHAGVALLPSSLAMQTTMLANSFILEEKQTSILYFIGGILGWPFALALGLPVGFYTIYQLSVL-LTVVVPI-MIIDSFFYQKV-SFIPINIVLYNVFG-EGPEIFGVEPFSYYIMNLLLNFNA-IFPLAVIGVFWNPI----------FV--SLWFGIFFAQPHKEERFLYPVYSLITLSAAILLSKL-----TIGLKNFIYR----FQLGFILSVSSLRILNLYGAPLQTFNTVNVCMGKEWYHFPASFFLPRLRFVD--SGFDGLLPGDFFESSTTFI-PMNNKNQF--EKD-KV-IDLEH-CHYYVDNSQLVYPN---LSTTGKWEVI-TCNKMLDKLLYVPGYMEFCLL Cangl ----------------LLVATRLQPFYSLISDCDETFNYWEPLNLL-KQTWEYSPEYSIRSWSFLLPFFYAVR--ILLGLFSLIQEWKLFKEITTLEIANFWLFYQLFNPGWFHASVELLPSAIAMILQLGSINYALKNFIGSLTNMIAGILGWPFVLVLNLPLCIHYVWTSLIF-LLISVIV-IGIDSLFYGKF-APVAWNIFFYNVLNAAGPNIFGTEPFSYYIQNLLLNFPITTLGFAVLGVSH-------------LWPLWTWFTVFALQPHKEERFLYPLYGYISLSASILTYKAL--------KVYFAF----VKLIIVGTQSLLRIFALYRAPMTVYSELNVCTGREWYHFPNSFYLPRLRFVK--SGFDGLLPGDFIEDAVRAV-PMNNRNMF--DES-KI-WPLEE-CDYFVDITLPFTG----SNSANRWNAV-VCQKFIDRAFAVPKYIDYCLY Capow SETTRSRFGSP--QEHQLLALRLAAIFSNISDCDETFNYWEPMHYV-MQTWEYSPEFAIRSYAYLLPHFYYVR--VVLAFLCAFSEAAFIHSALNVTIGRALLAFLLGSYGMFLASTAFLPSSFTMVCVMFAMACWMRSILGLVFIAIGAILGWPFCGAVGLPMAIDLLLLFLAI-LVVLLPT-VAIDSYFYGTP-VFASLNIVLYNVFG-GGPDLYGVEPLSYYLLNGILNTNV-AFLLSFVALPLTML----TLLI--LMPLYLWMAIFFTRPHKEERFLFPAYPLIYLAGAIVLEVVAAWS-SLLP---LARVARVLVRLALIVLSVSRGFMQYHAPLDVYGHLAVCVGKEWYRFPSHFFLPRLEFVA--SEFRAQLPQPY--SGTSGV-PFNDMNRE--EPS-RY-FDINK-CDYLIDVDTAREPRY--ALQTEKWKEV-YSVPFLDRAFYVPTYAKYVVL Catan2 -MDCKLRMPLANATTPLLVAARVGAWYSPITDCDETFNYWEPLHFA-LQTWEYAPQFALRSWAYIAPYFFAIR--IALALVCACFELKLTSAMSQTSAAVFLLLILAFSPGMFHSAPAFLPSSFAMICTLSAMSSWSTRPSLGVIIGTGSLLGWPFAAALGLPYALPYLVPVLVA-TAILAPM-LAIDSYMYARPWLLVPINLVMYNVIR-NQSALYGVESGAFYLKNLALNWTPPVLILALATTAVYLVTRGVAWMLAV------WLGVFTMQAHKEERFMAPAYPCVAVMAARGAAWTAREV--------WHRTLVV---LCAAAFAVLRMGALYAAPVRLDLSANVCTGNDWFLAPGHFHLPRIRFVR--QAFDGHLPADFAPSATSAV--FNDKNQV--TES-RF-VPLSQ-CDYILGRD--------PIVSRPSFTVA--CAPMLHRVLYHPVWQDYCLW Cioin -----------------------SALMNNVTDCDETYNYWEPLHHL-FQTWEYSPVYAIRSWAYICLHFYFIR--MIFGLVCTLCEIQFYKGVFGNNVARILLALMVLGTGMFISSTAFLPSTFCMFGTFLFMGLWLQKLNLAILVAASAIIGWPFSVALGIPLAVDILIRLVAI-ATMLLPS-FLIDSFFYGKP-VIASLNILTYNVFT-HGPDIYGTEPLSYYVINGFLNFNV-AFLLAIVIVPICEV----MLLISFIAPMYIWILIFFTRPHKEERFLFPIYPLICLSSAVTIATLQKLY-GFF------KFHRYIAALVLTIISLSRSFALYHGSMELYPKLRVCMGKEWHRFPSSFLLPTLELIR--SEFKGQLPAKFEAPGTRAE-PFNDENLE--EKS-RY-VDVET-CHFLIDFNHGHEPIY--SQQQDNWKIL-KEVDFLIRAFFVPDFGKYQLL CocheC53 ------TRP--HAARPVFAVANLAAAFSPIQDCDEVFNYWEPSHYL-LQTWEYSPEYAIRSWTYTAIHFYFLR--VILALFCALCQARMYSAIFQERIAIFFMIIMTISPGMYHAAPAYLPSSFAMYFAMLGFASFMDKTARGITFAIGSALGWPFAGALALLFILEDVIVGLSA-LAILAVQ-AGIDSFFYREP-VCVPLNIVLYNVFSGRGPDIYGVEPWHFYIRNLALNFNI-WFFLALVALPLLLIVSQHTLRRSVVSPFYLWLTIFTVQPHKEERFMYPAYPALAWNAALSLHIFLANF--------MDPRHLVIVCIPLLLVGMLRTIGHYSAPLNVYKPLMVCLGKEWYRFPSSFHLPRAKFIK--SEFSGLLPGEFSEGGTWMV-PMNDENRE--DSG-KY-IDIQH-CDFLVDSRFP-EPDY--ISETEQWETL-KCLPFLDRTLWIPKWGEYCLL Coere1 ------------------------ALLSPIQDCDEVYNYLEPLHFL-KQTWEYAPEYALRSYGYLFLHFFALR--IMLGLASAGCEALMIRMVVDKRMANYLAVGLFGMAGMFHSTVAMLPSSFAMCAGMVASAFAMVRMVPAVLFVVATAVGWPYAALVALPFVAEELLICGSG-AVIVGWL-AAVDSYYYGRP-VVATWSQIAYNVLGQGAAALYGTEPWHFYLKNGLLNGNI-VMVLALLALPLWLS---AHWLLLFMLPFHLVLVAFSMLPHKEERFMSIVYPHMCFCAAAALGLVRTLL--------FSRERLPTGFAVLGILGLLRMMALYAAPVRAFMELLVCMGEDWYWFPSSYWLPQLQFVTGLGHIGGHLPGNF--------------------------------------------------------------------------------- Conco1 IENIGLSVF-------ALILVRLSALYAFITDCDETFNYWEPTHFL-LQTWEYSPTYALRSYTYIGLHFYGIR--TVLTLFCAICETKFINSIISPKVANLTLLFLLFNSGMYFASAAFLPSSFAMYTTMLFTAKMIDRIKYCVFIALGALLGWPFSGAVSLPFIVNELYLIRAL-AIIMIPM-IVIEYFFYRKL-AIAALNIVFYNIFNPAGPDLYGTEPWTFYFKNGFLNFNV-ILPLALLAPTITAFKVFSTSNISI-----VWWLIFNIQPHKEERFLYVIYPLLCFNAATSLVLLNTIF-------LKGKSQVIYNLIFISSLSLSRTLSQYYGTMSIYLQSQMCVGSDWYRFPSHFLLPELKFVK--SNFDGLLPGYFLSDGSYHI-PLNNLNLE--ELD-KY-VPQET-CDFFIGTELP-QPNI-------TWSKL-DCTSIVDRAFLIPFHSKECCL Conpu1 TQTLRLRRTLQDQLRRLLLLIRVGAMYNNIQDCDEVFNFWEPLHYL-FQTWEVTPTYSIRSWAYILLHFFGVR--IFLAVISTLCEAQLCRAVINERVGRYLFVMLLFSAGMWNASSAFLPSSFAMYTTTLAFSYAVERTMMATLFATGAIVGWPFALALSLPFVIEELFVLTA--SLIFVPV-IAIDSVVYGKW-SVVPWNIIRYNVFGGRGPDLYGTSPWYFYVQNLLLNFNV-LIVLALGSLPALGVQSSPFTLLGLLAPFYLWIGILTAQAHKEERFMFPAYTLICFNAAVTLYLVRGWMEVAFIKVTASKTFMFMTFSVVATLSLSRVMALYHAPIMVVSQLRLCLGKEWHRFPSHYLVPRVEFIK--SEFDGMLPAHFGFGAARRM-PLNDLNKE--ASS-YY-VSVDD-CDYLVDLDFPHEPRY--AIGE-GWERV-ACMPFLDRTLWMPQFGDYCLL Copci SQALRQRRPLHDQVRRILFLIRVGAMYSNIDDCDEVYNFWEPLHLF-FETWELSPAFALRSWAYVILHLFAVR--IFLAAVSTLAEAAFYRAVVHVMVGRYLFLMLAFSAGMWKASTALLPSSFAMYATTVAYAYAIEKALVATLFATGAIVGWPFALALAFPFVFEELFVSAA--ALIFIPV-VAIDSIAYGKV-AVVPWNIIRYNIFGGRGPELYGTEPWTYYISNLVLNFNL-LTPMALLSLPALGVETSPFTITGLLAPFYLWIGILTLQPHKEERFMFPAYPLLCFNAALCIYLVRGWLETLYIKVTASKTVIFFTFSILVGISGSRICAEYHAPISVAFNFTLCYGKEWHRFPGNFLVPNVEFIK--SEFSGLLPTHFAPSQTHVA-PLNDLNIE--EPS-YY-VDVQQ-CDYLVDLDFPLEPRY--AIQSEVWERV-YCEPFLDRILWFPEFGDYCIL Croqu1 TQTVRFRRPIREQLNRIIVLVRFGAMYTAISDCDETFNYWEPTHYL-FQTWEYSPRFAIRSWAYILLHFFAIR--AAFAFISSYCEARLYRSIVNIRAARYFLAFTMFSAGMWNASTAFLPSSFALHAITLAYSYIIERTFSAILLATAVLVGWPFVGALAIPFVIEEVSMLTAL-ALIGIPV-FLIDTLAYGHS-VFVPLKIILYNVFP-SGPELYGTEPWYYYFLNLALNFNI-VFPLALASLPLLYIQSSAARLLLVLAPVYLWLSILSQQAHKEERFMYPIYTLISVNAAVTLSLMRGWLEDTFIKITAGRTSLFFTRSILAIISASRMLAIYHAPFDLLFHFRLCVGSEWYRFPTSFLVPEVRFIE--GGFRGQLPGRFV--GTRME-GFNSLNKP--END-RL-VKLET-CSYLITVEYPEEQVN--KVDEDEWDRR-ACWPILDRVLWFPKFGELCLR CryneH991 TETIRFRRPLQDQLKRLLLLVRTAAMYSIISDCDEVFNFFEPLHYF-FQTWELSPQFAVRSWAYILLHFFALR--ICLGTICSFCEAKFFRTVVNERVGRYLLFAMILSAGMWSASVAFLPSSFAMYTTMLASSYWFQRTYRATFYALGAIVGWPFSAALGVPFVFEQLFLTMS--ASIVLPV-YLIDSWVYGRL-TFPTLNIITYNLFSGNGPELYGTSPPSFYLANLFLNFNF-FVPLALLSLPALAVETSPYVLLATLAPFYVWFAILTAQAHKEERFFFPAYPLLCFNAAVTIYLIRGWMEKVYVHFTASRSSIFFTLLAVLLLSVGRIAATYHAPFDIVHHFSICYGTEWYRFPGSYLIPQVNFIK--TEFDGMMPRKWEESETRVIRAFNGENKASLEPG-TF-VDPSE-CTYMVSLSLLLEPDW--TRSP-EWEKE-FCTTFLDRLIYLPVYGEYCLM Crypa2 ---------AAHAMRRIFFVTALAALFNPIQDCDETFNFWEPTHYL-LQTWEWSPEYGIRDWLYIAPHFYFVR--YVLAAVCALCQTILYRVIIHPRIGAFFILATVLSAGNFHASTAYVPSSFTMYTGMLGAAAFMTRTAAGIAFAAGGIIGWPFAMFLCAPFLLEEALFCGVA-LLILAAD-SLVNSYFYRKPGIVVAWNIIDYNVLSK-GPNLYGTEPWTFYFKNLTLNFNL-WFLLSLVALPLFALRGFSSGLRTVLSPFYIWFGLFTLQPHKEERFMYPAYPFLALNAAVSAHILLTFL--------ISRRTVIFVVVPFLLVTVLRIIGVYGAPLSLYEPLFVCYGKEWYRFPTSYFLPQAKFIR--SEFRGLLPGEFAHHGTWMI-PMNDRNEE--DMG-KY-TDIGH-CNFLVDTQYPNEPDY--VADTDNWEVV-KCLPFLDRMLYVPKWGQHCLL Debha1 ----------------LNVLLRVAAFFMIISDCDETFNYWEPLNLL-KQTWEYSPDYAIRSYTYLIPYFYWIRLIALCGFTCFT-ELRLFYSILNRKVGNWFLFLSSIAPGMSHAGVALLPSSFAMNCVTMATANSLSYSVQAIIFLVGGIVGWPFALALGLPFGLFILIQIAGL-VSTLIIS-TAIDSWFYQKL-DLVPLNIVLYNVFG-EGPEIFGVEPFHYYILNLLVNFNV-VAILGYVGLVMNVV----------LITVSLWSLIFGSQPHKEERFLYPVYPLLILSSSLLLTLIFPMVKGIAANKIIEK----VQLLFAFSVSILRIINLYSTPLSVHREINVCTGREWYHFPNSFFLPRLKFIR--SGFDGLLPGDFLEGSTSSI-PMNNKNQY--SDD-KV-IDFDE-CSYYIDNSQAVERSGKELKVNKGWSVV-QCQNIINKLLWIPDYMDYCLV Dekbr2 ----------------SLIATRLAVFNSIISDCDEVYNYWEPLNFL-KKTWEYQPEYSIRSWTYLLPYFYLVR-LVLAVAFSFA-ECYLADAL-SGESSNWFLIFEIFSPGVFQASVSLLPSSFALIFGMFSTASIIKRYFASAVSTIGGIIGWPFCLVLTAPFVLYVVISVYMV-TWT---G-LEIDSLFYNKR-TIVPLNIVLYNVLHASGPNIFGIESSSYYFLNLLLNYHV-IFLFA-VANLL-TF----------LAAYRLWLTIFTLQPHKEERFMFPAYHMISISAASFASKIFK-------IVVI----CYARLVFLLVGGILRITSLYGAPLSAFKALNVCIGREWYHYPSSFFLKRLRYVE--NGFRGMLPGDFIEPSTRVD-QFNNLNHY--NPDFAN-AKLDQ-CDYFIDINMPILP---------GWQTI-RCEKMIDKLIHIPSKVYSCLF Dicdi KSQITNTNG-TEYITRLFFISSISAIYNRILDCDEYMNYWEPTHYL-LQTWEYSPTYSLRSYAYLLLHFYLIK--IGIGFFTSIAQTIFYRGVFGREISRYTLIFMLFSPAFFLSGSNFLPTSFSMTTFMAAYGFWMLEAIYSVFSATSVFMGWPFVIVLVIPIALNLMIRLLPV-IAVFIPM-ILIDYQYYGKW-VIAIYNIIAYNFTSNGGSQLYGIEDWPFYFINSFVNYNI-VFLFSLLTIP---L----TMVSIILCPYYIWFGFMTYLPHKEERFLFVIYPFIALAGSISFYIGLNILNAIILKISKKKNDDF----IIICLSVSRIYSTYTAPFNTLTHLNICIGKEWHRYPSNFFLPNLKFIE--SDFKGHLPKPFSTLGTAII-PMNDQNKQ--EFD-RY-IKPNE-CSYIIDFDSPNEEHY--VNDTSNWKVI-YSTKFLDRAFWIPVYNNYYIL Dmel SKKPPKR-PTSGGQEKTFVSARLSAIWAYIADCDETFNYWEPLHYI-LQTWEYSPQFGLRSYTYLLLQFYMVR--CMLGFGCAVMERYMYKSIFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAALAAWWQNYCFAIFTAISALLGWPFAALIGIPLVLEMLLRLISG-ATVAIPM-IAIDTSYFGKL-TFAPLNIVWYNVFT-HGPNIFGTEPLSYYIINGFLNFNI-IWLLA---LPIMLV----TLNFPHLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFSVVFK---KAGVHYLIAILVMVTLGLSRVFALYHAPMDLMLELNVCIGKDWHRYPGSFFFPRLRFLK--SEFRGMLPAYY-DEATKVV-QFNDLNQE--NEH-MY-FDYDR-CDFLVDFDEGLEPNY--SKRSKDWSVM-KSLPFLIRAFYVPQYGDFNLL Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 TETLRFPRPLQDQTRRILLLIRVGAMYSNISDCDEVYNFWEPLHYL-FQTWETSPQYAIRSWAYVALHFFALR--IFFGFVSSLCEAKLYRTVINFRVGRYMLFMLMFSAGMWNASTAFLPSSFAMFSNILAFSYSLHRTLYSTVFGMGAIVGWPFALAIAIPFVFEELFVACA--ALLFIPV-IGIDSLAYGHL-TIVPWNIVKYNVLGGRGPDLYGTEPWHFYIQNLLLNFNV-LTPLALLALPALAIRSSPFTLLAILAPFYVWFGIFTLQAHKEERFFFPAYPFLAFNAAVALYLVRGWLEAAYVKATASRTSWFTTLAVVFFISVARILALFHAPLEVAHHFTLCYGKEWYRFPGHFLVPNVEFVK--SEFDGMLPRHFVQSGTRYV-PLNDLNEE--DPR-HY-VDIKS-CHYLIDLDSPHEPRY--AIDDEHWQRM-YCAPFLDRAIWLPSYGDYCLL Fusgr1 ---------ASHAKKKWFLAAALSAWFAPIQDCDETFNYWEPTHYL-LQTWEYSPDYAIRSWLYIAFHFYFVR--FGLAFVCALTQTILFMVTLNSRIGLFFLMATVASPGNFHASTAFLPSSFAMYLVTLGAAAFMNKTSQGMFFAAAGILGWPFAAALCAPFMLEELILVVSA-ILLLAGD-YFVNLFFYKKQ-VSVTWNIVKYNIFSS-GPELYGTEPWTFYFKNLALNFNL-WFVLALAALPLFILQGFQTGLRTVLSPFYMWLAIFSSQPHKEERFMYPAYPFLALNAAISTHMILTAV--------SDPKTLVLVTITMLLIAVLRVYGIYSAPMKIYTPLTLCFGKEWYRFPSSYFLPHAKFIR--SEFRGLLPGQFSEAGTWLP-TMNDRNEE--DLS-KY-TELSA-CKFLVDTQYPNEPDY--IEDHTNWEVV-KCEFFLDRALWVPRWGRHCLL Galma1 TQELRFRKPLQDQLRRILFLIRVGAMYSNISDCDEVFNFWEPLHFL-FQTWEHSPVYALRSWAYILLHFFAVR--IFLATISVFIEAKLYRTIINDRVGRYYFFFMLFSAGTWISTTAFLPSSFTMYTSSLAFSYAFERTLLATLFATGGIIGWPFALALAIPFILEELLVLTA--ALIFIPV-VFFDSLAYGKP-TIVPWNIVRYNIFGGRGPELYGTEPWYFYLNNLILNFNV-LILLALVSAPALAVQSSPFTILAFLAPLYLWMGILALQPHKEERFMFPAYPLVCFNAAVCVYLIRGWLEVAFIGLTASQTLIFFTFSVVVAISLSRILALYHSPLTVAFEFKLCYGKEWYRFPGHYLVPQVEFVK--SEFDGMLPRHFEEKQTRFV-PLNDLNKE--DLS-HY-VPVHQ-CDYLVDLDFPFEPRY--TTMTDTWERV-SCHPFLDRMFWLPEYGDYCLL Ganpr1 MGDIRQRKPAPAVPTRLILIARLAATSSPIADCDETFNYWEPAHYL-LQTWEYSPDYAIRSWAYVALHFILVR--VLLGVCSAYAETSLCVAVWNARMARYLVAILVFGTGIFISATAFLPSTFAMYTTLMATAASLQRTIETVAYAVGVILGWPFSGLGVVPFVVEDVLTGVVV-IGILLPT-LLIDSAFYRRP-VFASLNLVLYNVFSGKGPDVFGTEPWWFYAVNLALNWNV-AFALAVLAVPFTLL-ATPTTIL--LADFPMWFLVFSAQAHKEERFMYIAYPGLVLCAAAALCCIGDVL------VGRRLAPLFSVPALLVVASLSRSVALYAAPLSVYAQLVVCVGKEWYRFPSHYFVPQLAFLR--SGFRGLLPKYFELDGTWLT-PMNDVNRE--ELD-RY-VDAAT-CDYVVDFASHGDHDY--C-NAAGFRRV-ISARFLNRIAWVPRWGEYCAM Gloin1 ----------------------------------QVFNYWEPTHYL-MQTWEYSPIYAIRSWAYIRLHFYAIR--VIFAVICSICEMLFYLSALGPRVGRYLIFTMLISAGMWNASAAYLPSTFAMYTTMIAFFYALNRIYLTIFVGLGSLLAWPFSAAAGIPAAIEELVLIVST-CMILIPL-VIVDYYYYKKI-TVVPLNIVIYNVFG-RGPDIYGTEPWNFYVINGFLNFNF-LFIMALISIPGLILPIYAYLYLIFLLPFYLWLFIFIIQPHKEERFLFVAYPLICLNSAVAIFLIRGWFDRLMSFRQARRYCMKLTAAIIIFISLARVSALYSAPMTIFKHF-LCIGKEWYRFPSHYFLPRLRFLK--SDFNGQLPKYFMEKGTWLV-QFNDRNLE--EMD-RY-FNVTQ-CDYIID----NEQKY--ITQTDQWSEV-ICKPFLDRALYLPKWGDYCLL Hisca1 --------QASKSSPKAFLLANTAASLAPIQDCDEVFNYWEPTHYL-LQTWEYSPEYSIRSWLYVSLHFYFVR--MALAFICAACETRIFAAILHPRIGVIFVTILVFSPGMFHASTAMLPSSFTMYTSMLGISAFMDNTGRGIMFGIGAIVGWPFAGALVVSFLLEEVLIVIKC-LIVLVLE-VVTDSLFYRKL-VVVPWNIVSYNVFGGKGPNIFGTETWTFYFRNLLLNFNI-WFLLALSAAPLLILTSKQTILRTVLLPFYIWFGIFTIQPHKEERFMYAAYPFLALNAAIAFHNILAYL--------SNRKEFIIALMPVLLISLLRTLGIYSAPLQLFQPLHVCFGKEWYRFPSSFFLPRAKFIK--SEFNGLLPGEFTTEGTWMV-PMNDQNQE--DPG-KYQINISQ-CNFLVDSYFP-QPNY--VLDKSTWEEI-SCRRFLDRIIWIPKWGRYCLL Klula1 ----------------LLLITRIQPYYSLISDCDETFNYWEPLNLL-KQTWEYSPEYSIRSWAFLLPLFYTAR--ALLGFVSFLFEYSLSKEIMSLHVSIMWLLFQLFNPGWFHASVEFLPSAFAMITTLGYMKYTLRPFVKSISVFLGGILGWPFSLILVVTNVIHYTATSFVF-AIISSIV-AAIDSFFYGKL-SVVPFNIVMYNIISASGPNIFGVEPWYYYIQNLLLNFPITTLFFGVIGFTQ-------------IWPLSGWLNVFLAQPHKEERFLYPIYGIISLLAAVGLFNIT-------VSIR-RK----VRGIVFFVQAASRILALYTSPIQVYSHLVVCTGREWYHFPTSLILPRLQFVQ--SGFDGLLPGDFLETKIRSV-PMNNQNIF--DPS-KV-VDIDS-CDYYVDINVSVNP----ADT-TAWVPL-YCLPFVDRAFQVPQFINYCTF Lacbi2 VQTIRFRGPLQDQLRRILFLVRVGAMYSNISDCDEVFNFWEPLHFL-FQTWELSPQFAVRSWAYILLHFFAVR--ILLAAMSVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 VQTISFRRPLQDQLRRILLLVRFGAMYSGIQDCDEVFNFWEPLHYL-FQTWEASPEYAIRSWAYILLHFFAVR--MFLAVISTICEATFYRAVINYRVGRYLFFMLLCNAGMWIASSAFLPSSFAMYANTLAMAYAMERTLFATLFATGALVGWPFALAVAIPFVLEELFLGVA--ALLLVPV-VGLDTLFYGKL-TIVPWNIVEYNVFSDRGSELYGTEPVQFYLSNLLLNFNV-LVPFALAALPALAVQTSPYVLLAVLAPVYIWTAIMTAQKHKEERFMYPIYPLICFNAAVTIYLVRGWLEAAFVAVTASQTSLFFTLSVVVTLSLSRITALYHSPMSVTYALRLCVGKEWYRFPGHFLVPRVDWIK--SEFDGMLPGHFKETGTMVA-DLNDLNRE--APE-FY-AEVET-CDYLLDLDFPHEPRY--IADEKTWERV-ACQPFLDRTLWMPSYGEFCLL Malgl1 ---------LYDVPKLIMLSVRMVACFMMVSDCDEVYNYWEPVHLLAFETWEYVPQYAIRSWAYAAMHFYALR--FALAVLSSVSDALLYEQVVHVRVARYLLVFLTVCAGMLSASTALLPSSFVMYTTSVAMAFAMQRTFYTTAFAFGALAGWPYAIILAAPYVYEELCLMYA--SLLAAPI-ILIDTLAYGRV-TVAPLNTILYNVASRISPELYGVEPPSYYVVALALAFSM-AAPLALAALPMIAIGSQRAVLLALVLPLYLWLGLLMTQPHKEERFLYPAYPLVCMNAAVTLYLVRACMEQAYLSITASRTMLFVTVMPLVVLGTLRIMALYRAPLQIGHAVTLCYAKEWHRFPSHFFVPQVAFVE--SDFRGILPHHFHKAYTRTV-PVNERNQH--EPD-RQ-------------------------------------------------------- Mellp23 TQSLRFRGPIREQLN------RFGAMYTAISDCDETYNYWEPLHYL-FQTWEYSPQFSIRSWAYILIHFFAIR--AAFALISSYCEAKLYRAIINLRAARYFLAISLFSAGMWNASTAFLPSTFALHAITLAYSYILERTFNAVFLATAVILGWPFVGVLALPFVFEELSMIMAL-VLIALPV-FLIDSLAYGQL-VFVPLKIILYNVFP-SGPELYGVEPWYYYFLSLGLNFNI-VSILALVSLPCLWLQSTASDLLLILAPVYIWIAILSQQPHKEERFMYPIYTLISFNAAVTLSLVRGWFEDAFVKATAGRTSLFFTRSILAIISAARIFAIYHTPLDIVFHFNVCLGSEWYRFPNRFLIPDVKFID--GGFKGQLPGRFLN-GTRMN-GFNSLNLP--ESD-RL-VDVEK-CDYVITL---NDEIL--KQESKEWGEICKCEKILDRLIWIPKFSKLCLI Mnele SSKLKYEND--KAAEKILTAARIAALTSHITDCDETYNFWEPSHFL-FQTWEYNPKFALRSYFYVGAHFYLIR--MMLGMFCAISEDQFYSAIFGAFVANCWLLTTLFAPGMFIASTSYLPSSFAMYSMTLAYAAWLDCNQASVLVAAASIIGWPFVAVLGIPIFWDIVIKFIAF-VYTISPL-ILVDLMLYKRM-VIAPLNIVLYNVLN-HGSTLYGTEPLSFYIYNGFLNFNI-AFCFALIALPCFAV----------LMPMYIWFAIMFSAPHKEERFLYPVYPLISFSASVVLYILWKSTSACFAYFYASILNIT----FFIILSCCRISALYRAPMHIFKDVTICIGKEWHRFPSSFFIPTVRFVK--SEFKGQLPQRFYPGGTSGINPQNDKNKE--EPS-VY-ISIKE-CDYLIDVDYGLEPRY--NLKS-GWTSI-KSYPFLNRAFNIPKYGNYHLL Monbr ---------------QLIMCRCAAATLSHITDCDEVYNYWEPTHYL-MQTWEYSPVYALRSWAYIAIHFYCLR--AVLALASAAAELSLYHAIFGTDTALAFAFFLGFSPGMFISSAAFLPSSAAMVLCTLAFAAW--------------ING------------------I---------PL-IGFDSMLYQKL-VVAPWNIVMYNVLSSTSSELYGTEPWHFYIFNSLLNFNV-AFILALLA-PVLTL----PRLLYLQAPLWVWLAIFVPQAHKEERFLFPVYPLICLAGAIGLSKAQYIC--------RILPTSLFQPLVLAVLALSRVGALYHAPLDVYARVTICVGKEWYRYPSSFFLPQLGFLQ--SEFKGQLPQPFAAEGTFAI-PMNDMNRE--EPS-RY-VELSS-CTALVDRA--LEPNY----DALGWKRA-FCSKFLDRALLLPTFSDYCLY Morel2 TATTTATTTLS--RWRTIFLVRAAATYSNISDCDEVFNFWEPMHYL-LETWEYSPLYAIRSWAYILLHFFIIR--IILGAVSAHCEATLYRAVVDPRIGRYLLLTLITSAGTWIASNAFLPSTFAMYTTMLFFSQMLQRTFWAIFVGLGGLLGWPFSAAVGLPFALEELLIIAVL-ACVLIPI-IVIDRYYYKKL-VVVPLNIVLYNVF--VGPDIFGTEPWWFYILNGILNFNV-LFIAALVSLPALLV----LLLFALLSPFYLWFAIFTAQPHKEERFLFVVYPLICFNACMTLFMV----QKLVQRGLRSKTAAILVWVVLIALSISRILALYSAPIDVYRRARVCVGKEWYRFPSHYFLPKLGLIK--SHFDGLLPGEFVESGTSHI-PMNNENKE--VHE-HY-TPLEQ-CQYLVDLDYSIEPRY--LQDKEKWERL-YCTKFLDRAFWIPVWGDYCLA Mucci2 KKQAP----L-----LILFIIRCSALYRIVDDCDEVYNYWEPTHYL-RETWEYSTDYKIRSWAFIFVNFYLIR--LFLAAVCSYVEARFYRTVINPHVGRYVFAILFFGAGMFNASTAYLPSTFAMYCVFMAFSYALRRTYKVVFIGLGALGGWPFAALIGVPFAAEEVLIVICG-GGLSFIL-MLMDQMFYRKY-TIVAWNIIKYNVLSNRGPELYGVEPWYYYILNGILNFNI-VFILALGSAVCVLIQIWPYVQLGLLVPFYLWFTVFSLQAHKEERFMYVAYPLVALNAAISIFLIRSWASRFAG--FNTRVIVLTSLVILLVLSISRITALYRAPFQVYTSLNVCVGKEWYRFPSQFFLPRLQFLK--TNFQGQLPQEFEEDGARQA-PFNDLNKE--NPT-VY-VKPEE-CDYLVDVDFPLEPSY--IRDTEHWEVM-DCFPFLDRAFWVPEWGDYCML Mydma EKLPRLRFP-------LLLSARIASFISTISDCDETFNYWEPTHYL-LQTWEYSPDYALRSYAYLLIHFYYIR--FFLGVICAACETYFFTSLFGNHVARLYFLIAAFSAGMFVSSTAYLPSSFAMYMVLVAYGGWFKNFLLAILIALGALVGWPFVALLGIPIAFDLIFFAFIF-VGIMIPL-VSIDTLFYGKQ-VITPLNIILYNIFT-DGPSLYGEESWTFYFINCFLNFNI-VFPIAVVSLPVCLL----VLLLPFLSPIYLWSLVFFTQPHKEERFMFPIYPLIIASACIALSKIQELYHSIFT---SKRQHYAIVAAVVIILSVSRVVALYRAPLDLYPEFNVCVGREWYRYPSSFFLPNYLFIK--SEFSGQLPQPF-AVGTKVV-PMNSKNIE--EPS-AY-SNIED-CDFLVDVNLQHELNF--SLMKKKWHIL-HSKKFLYRAFYVPTFIDYNLL Neucr2 --------PAKHAKKQIFLGANLAALFAPIQDCDETFNYWEPTHYL-LQTWEYSPDYAIRNWLYVALHFYFVR--CVLAFICALSQTLMWRAILNPRIGLFFIVALVFSPGNFHSSTAYLPSSFAMYMAMLGAAAFMNKTSMAMFFAIGGVLGWPFAAALCAPFLLEEVFFVVAA-GLLVFGD-MLVNTFFYRKV-EIASWNIVKYNIFSK-GPELYGTEPWDFYFKNLTLNFNI-WFVLALFSLPILLLETFQTGFRTVLTPFYMWLAIFSLQPHKEERFMYPAYPFLALNAALAIHTLLAAF--------ADPKSLVVVALGLLFIGLARIYGLYSAPLSIYKPLTVCFGKDWYRFPSSYFLPHAKFIR--SEFRGLLPGEFSEAGTWLP-TLNDRNEE--DPG-KY-VDPKT-CVFLVDTQFPNEPDF--VADTEHWEIV-KCEKFMDRALWLPKWGRHCLL Orpsp11 -----------------------------------------------------------------------------------------------------------------------------MYTTMLAFAISLKRTFFVIFYALGGLMGWPFSAVLVFPFVFEDIFIILSI-CIILGPM-MIIDYIYYKKW-TVVPLNIVLYNVF--KGPNIYGTEPWHYYLFNGFLNFNI-IFILALLSIPIFAF------LLILLLPMYLWIAIFTAQPHKEERFLF--------NNG----------KKLAK----------ILGIIFLILSITRNLSLYSAPMKIYSYL-ICVGKEWYHFPTHYFMPRLGFVK--SKFDGLLPGYFKEGGTWTI-PMNDLNQE--EFD-KY-------------------------------------------------------- Pench1 ---------------RLCLIANTAAIFSPIQDCDEVFNFWEPTHYL-LQTWEYSPVYSIRSWLYVSLHFYTIR--LSLAFMCAACQTRLYSAILSPRIGLLFVMIITLSPGMFHASTAFLPSSFTMYMSMLGLASFLDKTAQGIMFGLGTIIGWPFAGALIVPFLAEDAIVIIRC-LSILALE-VAVDYAFFRKL-VLVPWNIVAYNILGGKGPDIFGTEPWTFYIRNLLLNFNV-WFVLAMLSAPLLLFTSLQTSLRSMVAPFYMWFGIFSVQPHKEERFMYPAYPFLALSAALSFHIILTYL--------TNQKELIAAMSVVLVAGMLRTLGMYNAPLKVFEPLSVCFGKEWYRFPSSYFLPRAKFIR--SEFRGLLPGEFPDAGASQI-PMNDLNIE--DPS-KY-TDISQ-CSFLADSYFP-EPHY--LLDKAQWETL-SCASFLDRLIWIPKWGEYCLL Phybl2 ----------------VLLIIRCSALYRTIADCDEVFNYWEPLHYL-FETWEYSPEFSIRSWAYVALHFYLLR--MALGAFSSFAEAKFYRTVVNPHVGRYILAILFFSAGMFNASTALLPSTFAMYTTFLAYSYILRRTYKAVFLGMGALVGWPFSAVVGIPFAIEEILVILCG-AAISIPV-ILIDRLFYQRW-TFVPFNIVLYNVFG-RGPELYGTEPWYYYIVNGFLNFNI-VFILALGSALCVFVVIWPYVLLGLLIPFYIWFAIFSLQPHKEERFLFVAYPLIALNGAISLYLIRSWASRVAG--YETRAAVLTSLAVLIVLSVSRILAVYSAPLKIFGSINLCVGKEWHRFPSNFFMPRVRFIK--SDFDGALPKTFVEDGA-SA-IFNDLNKA--DPS-VY-VPLSE-CDYLVDSDFPNEPPY--VQDTATWETM-DCYPFLDRAFWIPKWGSYCLL Picst3 ----------------LNISIRISALYMIIADCDETFNYWEPLNLL-KQTWEYSPEFALRDYVYLFIYFYAIRVLALCGFTSYT-EISLFNNIIGSRVASWFLLFTSIAPGMSHAGVALLPSSFAMQCNTLAISYGISDFVIAILFVTGGLIGWPFALALGLTFGLYTLF-ASGT-ALILAVV-GVVNSYLYCKY-LLVPLNIVLYNVFG-EGPEIFGVEPFSYYILNLLLNFNV-VFPLAYAGSLMNPF----------FVVASMWSFIFFGQPHKEERFLYPIYPLICLNAALLTSKLFS--SQIFGKVVIRRV-WSVQGGFALAVSILRIINLYSAPLVVFSSVNVCIGREWYHYPNSFFLPRLRFVK--SGFNGLLPGDFNEEQTAFV-PMNNKNQF--EED-KV-VTLET-CDYYVDNTEPVLKDNGIIKANLGWDIL-KCHKLLRRFIYIPEYMEFCVL Plicr1 AQNLRLRRPLQDQLRRILLLVRIGAMYSVIQDCDEVFNFWEPLHYL-FQTWEVSPAYAIRSWAYILLHFFAVR--IALGLVSTLCEVRFYRTVINERVGRYLFFMLMLSAGMWNASTAFLPSSFAMYASTLAFSYAFERTLISTVFAAGAVVGWPFALALAIPFVLEELLVLAA--ALIFIPV-VGIDSLAYGRL-VVVPWNIVSYNIFGGRGPDLYGTEPWNFYILNLVLNFNL-LVPLALFSLPVLAAESSPFTVLALLAPFYIWIGILSLQAHKEERFMFPAYPVLCFNAAVTLYLLRGLSEVAYVTWTASQSSVFLTSSAILALSASRVLALYHAPKTVIFELRLCIGKEWHRFPGSYLVPRIDFVK--SEFNGALPGHFVEGGTRVV-PLNDLNHE--EPS-HY-VPVES-CDYLIDLDFPLEPRY--AVDEDTWERV-LCTPFLDRILWMPEFGDYCLL Polpo ATQIQNCEPMTELIAKCYVMMEVYGGHMLIIDCDEPMNYWEPTHYL-LQTWEYSPVYALRSYCYLLIHFYLIK--IFIGLNSAFAQTIFIRGVFGNKISLLTTLFMLCNPGLFLSTTTYLPTTFSMITIMFGYGFWMLRPLLSVFCAVSVFLGWPFVIVLCVPIALDLLYRIIPT-VSVLLPM-MAIDKQYYGKT-VLAIWNIIAYNFTSSGGSQLYGIEHWTFYFINCFVNFNI-VFLLSMLTIPLYFL----PRVLTLVSPYYIWFAFMTYLPHKEERFLFVIYPFICLTAAITIYLVINILKQLFL---HKKSDD-LQVMVVVLLSASRIFSTYTGAIDTYTYL-----------PKFAFNK----VN--SNFKGHLPKPFT--GTSNI-PMNDRNQE--ELD-RY-LDVSR-CHYIIDFDYPQEPHY--TVDPS-FTPI-FTTPFLDRAFYIPKINK---- Pucgr2 AQTIRFRKPIAEQINRILVLVRFAAMYSSISDCDETFNFWEPTHYL-FQTWEYSPDYSIRSWFFILIHFFAIR--AMLAFLSSYTEAKLYRAIINPRAARYYLSMSLFSAAMWSASTAYLPSAFAMQAITLAYSYVLERTFLSCLFVIATVAGWPFVGVLALPFALEELSLLACV-VMISAPI-VFVDWLAYGKL-LFVPLNIVMYNVFPGGGPELYGTEPAYFYLLNLLLNFNI-VFILALLSIPLVLFQTPSSHLLIVLVPVYAWIALMSQQPHKEERFMQPIYTLISFNAAVSLSLIRGWMEDIFVKMTAGRTSIFFTRTVILTIAIARILALYHAPLDLMFHFTLCLGDSWFRFPTQFLVPNVEFVK--SPFEGILPSKFQSSGTRTN-GFNAQNKE--EAD-RY-VDPESQCSYAIGLNYPEDATL--------WEPR-RCVKMLDRTVWLPSFGELCLY Punst1 VQTLRLR--LQDQVRRLLLLVRVAAMYSNISDCDEVYNYWEPLHYL-FQTWETSPKYAIRSWAYILLHFFATR--IFLAVLSTLCEAKFYRTVINLRVGRYLFFMLLFSAGMWNASVAFLPSSFAMYAVTLAYSFALARTYSATAFAVGALLGWPFAIALAIPFVFEELFVALA--SVVLVPI-VLVDSYFYGKL-TVTPWNIVSYNIFSDRGPELYGTESPAFYFLNLALNFNL-VLPMALLAIPSLILQSSAYTVMGILLPVYIWLGILTAQAHKEERFVFPAYPLICFNAAVTLYLVRGWMEVAYVKVTASRTSIFTTLSVILYISLTRILALYHAPLSVVFRLTLCIGKEWHRFPGHYLVPDVQFVR--GAFEGLVPGKFAPAGTSRV-PQNDLNKA--EES-HY-VDVDQ-CDYMLDLFLPREPPY--AISE-AWEKA-HCAPFLDRTVWLPAWGEWCLL Rhior3 TKET-----L-----LVLFIIRCSALYRIMDDCDEVFNYWEPTHYL-RETWEYSTDYKIRSWAYVFVHFYIIR--LVLAGACSFAEARFYRTIINPHVGRYVFAILFFGAGMFNASTAYLPSSFAMCCVFMAFSYALKRTYRVVFIGLGALAGWPFAALIGLPFAIEEILVFFSG-IGLVFLL-VLMDQMFYRQY-TIVAWNIVKYNIFS-RGPDLYGTEPWYYYILNGFLNFNI-VFLLALGSAVCVLIQIWPYVVLGLLIPFYIWFITFSLQAHKEERFMYVAYPLMSLNAAISIYLIRTWASRFAG--VHVRVMALTSFAILFVLSFSRILALYRAPLTIYSSINVCVGKEWYRFPSQFFLPRLQFIK--SDFHGQLPKTFEEDGARQA-PFNDINME--DPS-VY-VDENE-CDYLVDVDYPAEPRY--IKDTDHWEIL-ACYPFLDRAFWVPAWGDYCML Rhoto1 AQQLRFRSKLKDPNLRFLLLVRWSAMYTAIGDCDEVFNYWEPLHYL-FQTWEYSPAYAIRSWFYLLIHFFATR--LMLATFSSFVEAVFYRACLSSHVGRYVLWIQMFSAAFYSAATTFLPSTFALYFVMLGTAASLSRISFAVAYGMAGIVGWPFAVLLGVPLILEQLFVTLG--ATIAVPV-VLVDSAAYQKL-TIVPLNIIKYNLFPTAGPELYGTEPWYYYILNGLLNFNI-LFPLAVLSLPFILVQTHPAASLAILVPLHLYLAVLMLQKHKEERFLFPAYGHVVLNAAVAIYLARGWVEAAFLKVTATRTGLFFTRAVIVFLSFARISALYHAPFNVFHHLRLCIGKEWHRFPSSWLVPETRFIK--SEFDGILPKV----ATAVE-PMNMFNRE--EKD-RY-VPVAS-CDYLVDLDFPIEPRY--AADEAHWDKV-YCHPFLDRAIKLPSWGEYCLL Rozal11 DSAQNENAPQNDAGESFFTIVNICAYFATMDDCDEVYNYWEPLHFL-MQTWEYSPNFALRSYLYLGIYFYALR--IITGILCAFGQSFFYETVIHPEIANSLVYCLAFSAGNFISSTALLPNTMSMIIVFFIYGYWFRRFNPILLTVMCICVAWPFALIIILP-------------ALLYIPTCVLIDNNIEKDLTINLDFEWAMFNRIKQAGPELYGTSPFYFYFFNCLLNFNV-FFLLAIISFPLSFL----YQAIRLLYPFYWAFVFFSIQAHKEERFLF------------------------------------TRSIIIVLLSASRILAVYDNSKALYELVNLCLSNEWYRFPSHFYLQSLVFLR--EGFHGLLPKYF---ATNET-SVNYLNRE--ELD-QY-GKRKS-CDFFITETRAEISSFNANDLAENFTVV-NCISEVDRSFYIFTYLQYVYL Sacce1 ----------------LLFLTRVQPTFSLISDCDETFNYWEPLNLL-KQTWEYSPEYSIRSWAFLLPFFFITR--ACLGFFSFIMEFKLHREILALQIANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRNFTKSLANFLASILGWPFVLILSLPLCLHYLFNCLIF-SLTAFAV-IVTDSIFYGKL-APVSWNILFYNVINASGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFH-------------LWPLWAWIAVFTQQPHKEERFLYPIYGLITLSASIAFYKVL--------NLFLKK----IKLSVLLIQAMSRIVALYTAPIAVYEQFNVCTGREWYHFPSSFLLPRLKFVK--SGFDGLLPGDFPESKIRTL-PMNNKNIY--DTG-KE-WPITR-CDYFIDIVAPFNP----LHLMDNWNKL-ACAAFIDRAFYVPRYIDYCLF Salro ----------------LVLGARLSALFSNISDCDETYNYWEPLHYL-FQTWEYSPEYALRSYAYLDLHFYAVR--VALAMLTGASEITLYFTLFGHQVPLLFVLFSSLSCGLFISSAALLPSSFALALSTFALAAWYRQDFWAVLTAISAIAGWPFAAALGLPIAVDIVVMVIALCVCVCAPL-VAADSYLYGRL-VIAPLNILTYNVFSSTSSELYGTEPWEFYFLNGALNFNV-AFPLALMA-PIFML-APSSRLTAFLAGMWIWLAIFVPQAHKEERFLFPIYTLVALSAAIALARIQQFW--------ALAPTKLVQAAVIVVLCASRVASLYHAPLDVYARLRLCVGKEWYRFPSSFFLPEVEFIR--SEFKGLLPKHYEAAGTRVI-PMNALNKE--EPS-RY-VPVET-CDFIVDFE--LEPNY--G-DDASWTRV-ACAPFLDRTLYLPVFRDYCIY Schco3 TETLRFRRPLQDQVRRWLLLIRFAAMYANITDCDEVFNFWEPLHLF-FQTWEVSPEYSIRSWAYIVLHFFAVR--AVLALASTLIESYFYRSVINERVGRYLFFMLSFNAGMWNAAPAFLPSSFAMHACTLAFAYVMERTLAATVFATAAIVGWPFSLALAIPFVYEELFVLLA--GLVAIPV-IAIDTAAYGKL-TIVPWNIISYNIFGGRGPELYGTEPWSFYILNLLLNFNV-LLPFALLSLPALLLQANPTLSLALLAPFYLWLGILSAQPHKEERFMYPVYPMLCFNAAVAVYLVKGWMEVIFIKATAAQTSIFFSSSVVLALSISRIMALYHAPQSAYFQFTLCVGKEWHRFPGHYHVPRVEFVK--SEFSGLLPGHFGEDVTRLV-PQNDLNIE--EPS-HY-GSVEQ-CDYMVDLDFPLEPRY--ALLE-EWERV-ACYPFLDRALWMPEYGDYCLL Schpo1 ------------MPSKILAVLRLSASFRVIDDCDEVYNYWEPLHYL-LQTWEYSPEYAIRSWFYIALHFYFIR--GVLACFSAFCETNLILAVFNRAVALHLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSRTVKVVSITIGAVIGWPFSAALSIPFILLELVDFVA--LLITGIC-ITVDSLFYHRI-QFVAWNIVKYNVLAKRGPDIYGTEPWWYYFANLSLQHNI-VLWFAMACGPLVLL----------ISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLM----IQILTVRSKFPVVLCVYAILSIARILAIYNAPMIIYPAINVCVGKEWYRYPSTFFLPRLKFVK--SEFDGILPGEFVESGYYQI-PMNEFNNE--EPT-RY-TSLES-CDFLIDLEFDNEPIY--S-KSDGWIPV-MVYPFIDRAFAVPKWGRYEIL Sorma --------PAKHAKKQIFLGANLAALFAPIQDCDETFNYWEPTHYL-LQTWEYSPDYAIRSWLYIALHFYFVR--YALALVCALSQTLMWRAVLNPRIGLFFIVALVSSPGNFHSSTAFLPSSFAMYMAMLGAAAFINKTSRAMFFAIGGVIGWPFAAALCAPFLMEEVVFVVAA-GLLVFGD-MLVNTFFYRKV-EIASWNIVKYNIFSK-GPELYGTEPWDFYFKNLALNFNI-WFVLALFSLPILMLETFQTGFRTVLTPFYMWLAIFSLQPHKEERFMYPAYPFLALNAALAIHTLLAAF--------ADTKSLVVVAFGLLLIGLARIYGLYSAPLSIYQPLSVCFGKDWYRFPSSYFLPHAKFIR--SEFRGLLPGEFSEAGTWLP-TLNDRNEE--DPG-KY-VDPKT-CTFLVDTQFPNEPDF--VADSKHWETV-KCEKFMDRALWLPKWGRHCLL Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 QKVKGQETP------TALCVARLAAIYSNISDCDEVFNYWEPTHYL-MQTWEYSPKYSIRSWAYISLHFYETR--GALALASALCEAQLYDAVIGPRVGRYLLFILLLNTGMFISSTAYLPSTFAMYSVTLATAYFLQRTYAVVFIGLGALVGWPFSAAIGIPFVMEEVLLLLAL-VLILGPL-IIVDYYFYNKW-TIVPLNIVVYNVFG-RGPDIYGTEPWWFYLINGALNFNI-IFPAALASLPAILLANYNVWALAAMLPMYLWLAIFTMQPHKEERFLFVVYPLICLNGALMLYFARSWIEKLFA---KSRATAIFTRVVLILLSISRSLSLYHAPMNVYPHL-LCVGKEWYRFPSHYFLPRLRYLK--SDFAGLLPKYFEEEGRRLT-SMNDRNEE--VMD-RY-VDVGT-CDYIVDY---SQPAY--ALDTNTWAKH-HCAPFLDRAFYIPVWGEYCIL Sporo1 GQQLRFKKSLKDHNLRLILLIRFSAMYTSISDCDEVFNYWDPLHYL-FQTWEYSPEFSIRSYFYLLIHFFATR--IMLASFCSLIEAVFYRAALSSHVGRYVLWITMFSAAMYSSSAAFLPSSFALYFVMLGTAASLSRITFAVSFAVAGIVGWPFAVLVGIPLILEQLFVVVG--STVAIPV-ILVDSSAYQKL-AIVPLNLIRYNLFPVAGPELYGTSPWYFYILNGLLNFNI-VFPLAFLSLPMLYLQTSPATSLAILAPAYLYVAVLTLQKHKEERFLFPAYGNIILNAAVTIYLARGLFEQAFIKVTATRSGIFATRAVIVLISFGRISAIYHAPFNVYHHLRLCLGKEWHRFPSSFLVPETRFVQ--SAFDGILPKE----ATAVK-PMNMYNRE--EKD-RY-VDVST-CDYLVDLETPLEPRY--SLDASSWEKV-YSHPFLDRTFNLPKWGEYTLL Stehi1 YETLRLRRPLQDQLRRILLLIRVAAMWGNIQDCDEVFNFWEPLHYL-FQTWETSPAYAIRSWAYIILHFFAVR--TFLAVISSVCEASLYNTVINNRVARYLLFMMATSAGMWNASIAFLPSSFAMYAVTLACSYAFVRTLAATLFATGAIVGWPFALAVAIPFVLEELFLAAA--AQVAVPV-IVIDTFFYGKI-VAVPWNIVKYNVFPDRGPELYGTEPWTFYVLNLLLNFNI-LLPLALLSLPALFVNSSPFTVLAFLMPMYIWMVILNIQPHKEERFMFPVYPLICFNAAVSVYLMRGWLEVAFVKITASKTSIFSTLSVIVFISLARILALYHTPMTIVYHFRLCVGKEWYRFPGHYLVPRVDWIK--SEFDGQLPAHFTVTGTSVV-PLNDLNKE--EHM-HY-VNAST-CDYLIDLDYPYEPRY--AVDEKTWDRV-SCLPFLDRTLWLPKFGDYCLL Tapde11 ---------------------------------------------------------------------------------------------------------------MFSASTAFLPSSF--------------QYLGATVFGIGAVLGWPFSVILFMPVVV-----SQV----------LLISTVFYRIW-TLVPLNIILYNVLAARGPEVFGVEPVSYYFKNLLLNFNI-MFPLALIAVPV-VL----------TACF--WILVFSLQPHKEERFMYPVYPALVLNCAISLRAILETF-GTTNVYIIQKDALQCKICFILTLSVLRISLMYSAPLALFPSLRYCIAGDWYRFPTSFLLPSLSFVE--SDFKGLLPGKF---DTWTL-PMNDQNMW--SAD-KV-IKLSD-CDALVSWKPEKHPGY------YGYESL-KQENSAD-------------- Thetr --------------MGALLVALVAVFMAPIPDCDEVFNYWEPLHYL-LQTWEYASQYALRSYAYLLAHFFALR--LVLVILAIYVFSALYYVLRFSHIPIFVLVFMALAPGLFLAVPAFVPSSTAMVALTAAYAAFLDREALAVAVGVAGLVAWPFAAWAGVPIALHMMFLLLAG-TVLIGLL-LAIDSSFYGSP-VLAPLNIVMYNVLATGGSELYGTEPWHYYIRNGIVNFNL-AFVLGLTVLPGWLS----------LWSIWAWLGLMLAQPHKEERFLYPIYPALCVSAAVTLACGASLLKAAFV----TRASLTLVWMILALLAVSRSVVMYGAPLEVYTHLAVCVGKEWYRFPSHFFFPALHFID--GGFGGLLPQAYAPLGTL---P----------------TTVPT------------------------WSI----------------------- Treme1 TETLRFRRPLQDQVGRLLLLMRTGAMYNVIADCDEVFNFFEPLHYF-FQTWELSPEFAIRSWAYVLLHFFALR--IFLGAISSYCEARFFRAVVNERVGRYLLFMMMLSAGMWGASVSFLPSSFTMYTTMLAAAEWLHHAYRGTFVAVGAIVGWPFSAVLGIPFVFEYLFLIGA--ACVAIPI-YLIDSWAYGRQ-TFPTFNILIYNLFPSGGPDLYGTSPIHFYFLNLLLNFNF-LFPLSLLSLPLLCLETSPYTLLFMLLPFYLWFTILSLTPHKEERFLFPSYPLLCFNASVSLYLLRGLIEGLFIKLTASRSNIFFTLLVVIFISIGRLVGMYHAPLDLAYHFTMCWAGEWFRFPGSHLFPDVKWVK--TEFDGMMPRKWEPSETRVVRPFNGQNKASLEVG-TY-FAVEN-CTYLVDLSLPLEPDY--TSDE-RFIRE-WCTTFLDRLIWLPVYGKYCLL Trire2 ----RAAAPASHAKKKLFFGANLAALFAPIQDCDETFNYWEPTHYL-LQTWEYSPDYAIRSWLYIALHFYFIR--YGLALLCAICQTIMFQSILNARIGVLFVIATIVSPGNFHASASFLPSSFAMYMAMLGAASFMNKTWQGMAFAVAGILGWPFAAALCAPYLLEEFILVIAA-FLVLGFD-FTINLFFYKKS-VVVAWNIVKYNIFSK-GPDLYGTEPWTFYFKNLALNFNI-WFILALLVLPLFILQSLASGLRTIIAPFYMWLGIFTAQPHKEERFIYPAYPFLALNAAISVHIILYAL--------SDAKTFVVVGLTFLLVSLARIYGIYSAPLKIYSPLNVCFGKEWYRFPTSYFLPHAKFLR--SEFRGLLPGEFSEAGTWLP-TLNDRNEE--DLG-KY-VEPRM-CSFLVDTQYPKEPDY--IADQNHWEVV-KCVPFLDRTLWVPKWGRHCLL Umbra1 QNQPPAEPK------LLIFAVRCAALYSILSDCDEVFNYWEPTHWL-LQTWEYSPEFAIRSWSYVSFHFYFMR--IMLGAMSAFAEARFYRTVINAHVGRYLLVALIGSAGMFHASVSYLPSSFSMVTTMLAFSFVLQRTYGATFFGLGGLFGWPFCAILGVPFVIEELLVGLSF-FAIAIPI-LAIDYYFYEKL-EFVPLNIVLYNVFG-RGPNIFGTEPWSFYIVNGFLNFNI-IFLLALGSGVCVLIAVSPYILLALLVPFYIWLAIFTLQPHKEERFLFVAYPLICLNASIALFLVRGWVHRVTG--VSTRLYTVTTAAFLLILSLSRILALYGAPKEVYSALTLCVGKEWYRFPSSYFLPRLGIIK--SDFDGLMPKPFAEDGASVI-QFNDLNKE--DPS-AY-TDIFQ-CDFLVDSDFPYEPRY--IQDTDHWNVL-KCVRFLDRAFWIPQWGEYCLL Ustma22 SQGLRFQQQLQDYAKMFLIIIRVSAMYSVIKDCDETFGYWEPLHLLPFQTWEYSPQFAIRSWAFIAQYFFAVR--LLLAFVSSFVDARFYKAVFSARVGRYCLIALATSAGIYEASTAFLPSTFVMHATTLAFSSCLYRLLLAAFFATGAIIGWPFAIILALPFVIEQLLLVLS--TILGLPA-VAIDTLAYGKL-SFVPLNTVLYNLFSRAGPELYGTEPLTYYFSNLLLNFNV-FFLLALLSLPLMLVPSSLFSLALLIAPFYLWFILLSVQPHKEERFMYPAYTLLCLNAAVSLYLIRSLAEVGFVQVTASKSSVFITSSVLAILGVLRSVGQYHSPFDVLFHFRLCYGKEWHRFPTHFLVPEVEWIQ--SDFDGILPKHFDVDITRRV-QFNDLNQQ--EMD-RY-VDVST-CDYLVDLDLPYEPRY--ASMSDEWDRV-FCGAFLDRAFWLPLYGDYCLL Walse1 -------------------------MNSIITDCDESYNYWESMHYL-FQTWEYSPVYSIRSWFYIIINFFGTR--SYLGLLSSVIEASFYSSVFNPRVGRYLLAFLIGSAGMYISAIALLPSSFTLYTTTLGYAFAIKRCLFATLFAFGAIAGWPFALTLAGPFVIEQLFMVVA--SLLFIPV-VAIDSLYYGKL-TVVPLNIIEYNIFSE-GPTLYGVEPPHFYVLNLLLNFNF-VFLLAVASLPLAAL-----TFVTILLPFYGWFALLSLQPHKEERFMFPSYALLCLNAAVGLYYLRTLISTSYSHLVSSKVVISLTVSIVIILSVMRILAMYHAPIDILFEFTLCYGKDWYRFPSSYLIPDVQFIE--SEFDGILPSH----NIRRI-PMNDQNKQ--ERD-RF-VPVDS-CDYIVDVVLPLEPDF--AN-SNDWTIA-TSLPILDRTLYLPTFGEIRLL Zygro1 ----------------LLSLSRLQPVFSIISDCDETYNYWEPLNLL-KQTWEYSPEYSIRSWSFLLPFFYITR--FLLGLLSLVLEIGLHWEIMSMRVANLWLFFQLFNPGWFHASVELLPSSIAMLLSIGSIKYALRPFILSMATFIAGVLGWPFVFLLGLPLCFHYLITGTVL-TLVVIMV-VGLDSLIYGKF-TPVSWNAFWYNVVDASGPNIFGTEPWFYYILNLVLNFPLPVLVLAPLGLFH-------------IWPLSLWLAIFMVQPHKEERFLYPIYGFVTLSAAVGYEKLV--------SLFLHK----FQLGTIATLATSRIAALYGAPLQVYGELNVCTGREWYHFPNSFLLPRLKFVA--SGFDGLLPGDFPEEQIRQI-PMNKENQF--DEG-KL-WPSDD-CDFYVDIFKPFNP----LWMPSDWDKI-SCHKFIDRSFYVPGQTDYCLY [Cluster2217.fasta_al_trimmed; alignment length = 96] Allma1 RDLRACKLCSLIKTLSQFGCDNCEEILDLRRHPS-RVCTSSTFEGAIAMLKP--ERSWVAKWQRV-DPGLYAIRVGRIPEDILEQR-GIRDGTAGD Ashgo11 SSDRACMLCGIVQTTNEFGCPNCQGIF-----EEASVCTSPSFEGLVGMCKP--TKSWVAKWISV-EQGMYAIKVGRLPVEVLPH----RDGSQVD Aspfu1 RTLRACMVCSLVQLHSKFGCPNCDNVLGLRGNND-AICTSQVFEGLITLRDP--STSWVARWQRL-EGGTYAVKVGSLPDDVLEDS-GVLPGSCVS Aurde31 KGLRACLLCSVIQTVGEFGCPNCENILQMQNSTD-RVCTSKFFTGIIAVMNP--DQSWVARWQRT-AKGMYAIQVGRLPEDVLVQQ-GMRDGSMDD Batde5 RKLRACLLCSLLKTQQRFGCDNCEEVLLFKNNTE-RMCTSANYDGVIAQMKP--EVSWVARWQRV-DKGLYAIRVGQLPYEVLIDK-GIRDGSVKD Botbo1 KHLRACLLCSVIMTPADFGCPNCEEILNMQGSAD-RICTSAQFDGVIAMTQP--SESWVARWQRV-DRGLYAARVGKIPLDVLVNR-GIRD-QIQE Botci1 RNLRACMVCSIVMTQNRFGCPNCEDFLHLQGSME-AICTSQVFEGLITLADP--SKSWVAKWQRL-DGGVYATKVGQLPEEIMEEEARVRDGSATE Caeel RNLRACLLCSLVKSVESFGCENCEDVLHLKGDEE-KVCTSANYDGMIAAMSN--NESWVCKWQKM-QRGMYAISVGVLPNNILKSL-GVRDYSTQF Canalb1 RSERACMLCGIIQPMKSFGCPNCESLLHYQYNDNKQVCTSPSFEGLVALGED-NKGSWVARWLRI-DSGLYAVKVGKLPPSILEEQ-NVRDGSAED Cangl SSERACMLCGIVQTTNEFGCPNCQGIF-----EEAGVCTSPSFEGLVGMCKP--TKSWVAKWLSV-DAGMYAVKVGRLPPEVLPH----RDGSQVE Capow KDLVACMICSLLKNANQFGCENCSQVLEELGIDQ-ENLTTKNFEGMVALMKP--DVSWTGRWQSI-SKGLYAVGVDRPPKEVLANQ-GLRDGRDR- Catan2 RNLRACLLCSLVKNASQFGCDNCEEILQLRGRPE-RLCTTSAFEGTIAMMNP--RRSWVGKWQRI-NPGLYAIKVGRLPDDVLERS-GARPPINVS Cioin RNMRACLLCSLIKTMDQFGCDNCDEYLHMRGNRD-MVCTSSSFDGIISMMAP--DESWVAKWQRI-KKGCYAISVGRLPSSMLKAN-GVRDTSQKA CocheC53 RNMRACMVCSIVRTQQQFGCPNCEEFLELTGNPE-QICTSQVFEGLITVADT--TKSWVARYQRL-EGGVYATQVGILPDDIIESA-GVRDGS--E Coere1 RQLRACLICGIVQNHHVFGCPNCERLVKMAGQSD-VVCTSGTFDGITAVLQP--RMSWVCKFAHV-NNGVYAAHVGRIPEDILAQN-GIRDGSADE Conco1 RQLRACMLCSLIKTAAQFGCDNCESILKLTRSTE-RICTTTQFEGMIALTKP--RESWIARWLRT-ENGLYACQVGVLPDYILSKV-NIRDGSYQD Conpu1 KQLRACLLCSIVQHPMDFGCPNCEELMQMKGSPD-RICTTTYFDGIIAVIDP--ESSWVARWQRT-SKGMYAVRVGRVPEDILENR-GIRDQTDQD Copci KQLRACLLCSIIQLPADFGCPNCEEILQLKGNTD-RICTTTYFEGVIAVIDP--DNSWVARWQRT-SKGMYAVRVGRVPEDVLEAR-DIRDQTETD Croqu1 SKLRACMLCSYVQTAQSFGCPNCDDLLEMKGNSD-KVCTSGTFDGTVAVMKP--DESWVAKWQRI-NRGVYAIRIGSLPEAILEHQ-G-RRDDD-- CryneH991 AELRACLVCSILQSTNDFGCPNCEDILEMRGSAE-RVCTSLLYDGMIAMIEP--SESWVARWQRI-DKGIYAVRVGRAPQDVIEAR-GGRDAVED- Crypa2 RGKRACMVCSIVLPKTEFGCPNCEEYLHLAGNEE-AICTSSVYEGLIALADP--ARSWVAKWQRI-DKGTYATKVGTLPPDVLLEEYNIRDGSAGN Debha1 RSERACMLCGIIQPFRKFGCPNCESVLHFQDNEDNQVCTSPSFEGLVALGDE-TKSPGGER-LRI-DSGLYAVKIGKLPPHILADQ-NIRDGSAED Dekbr2 KLNRACMLCGVVQSMTEFGCPNCESVLHFTDNED-MICTSPTFEGLVAYKGE--KTSWVARWLRI-ENGMYAVRVGKLPEDILYSQ-GIRDGSVRD Dicdi KHARACTECGLVKSAQQFGCENC------SS-----SSTTQNFEGIIAIMNP--KESWIARRLQF-ERGLYALSM----DSD-------------- Dmel RGLRACLVCSLVKSFDQFGCENCEEFLRMKNNKD-NVHTSNNFDGIIALTTP--TDSWVAKWQRL-SRGIYAISVGTLPQSTMKNR-GIRDRSQR- Enthi NTLRCCKICGLIKSQEQFGCDNCKRYFD---NWE---YVSSNFTGMLSLLRP--DRSFIGKVLGMKDTGLYAASCDSVSPEIATVN-DIRK----- Falba RRIRACTGCKFLNSLDNFGCPNCGP----------GV-ITRTYTGTLAITNP--NVSWVAKWKNIPANGLYALEIEYYEDDYEEFEAGGSDDDL-- Fomme1 RQLRACLLCSIIQSPVDFGCPNCEEIMQMKQSQD-RVCTTTHFEGVIAAIDS--EASWVARWQRT-SKGMYAVRVGRIPDDVLQER-GIRDQTDQD Fusgr1 RNLRACMICSIVMTSQRFGCPNCEEFLHLQHSPD-QICTSQVFEGVITLANP--TKSWIAKYQRL-DSGMYAIKVGQLPDDVLEDEYRIRDGTEVE Galma1 KNLRACLLCSIIQTPAEFGCPNCEEILQMKSSPD-RICTTTQFDGVIAVIDA--DQSWVARWQRT-AKGMYAVRVGRIPEDVLERR-NIRDQTDQD Ganpr1 RRLRACLVCSILKSQRQFGCDNCEPILKLKGSSA-RICTSANYEGIIAMMNP--EQSWVARYQRI-NAGLYAMRVGRLPEDMLESR-GVRDGSGGR Gloin1 ------------------------------------------------------------------------------------------------ Hisca1 RSLRACMVCSIVQVHSKFGCPNCDHILGLAGNGE-KICTSQVFEGLITLADQ--QASWVARWQRL-EGGTYAVKVGTLPPGVLEDS-GIRDGSSID Klula1 STDRACMLCGLVQSTAEFGCPNCQSIF-----EEAGVCTSPSFEGLVGMCKP--SRSWVARWMSI-DSGMYAVKIGRLPIEVLPH----RDGSQVD Lacbi2 KQLRACLLCSIIQLPVDFGCPNCEDVVQMKHNPD-RICTTTYFDGVISVIDP--DKSWVARWQRT-SKGMYAVRVGRIPEDVLENR-GLRDQTDQD Lenti61 KQLRACLLCSIVQTPADFGCPNCEEIMGMKGYAD-RICTTTHFEGVIAVINP--EDSWVARWQRT-SKGMYAVRVGRIPEDVLESR-NIRDGTDQD Malgl1 AKLRACLRCHFAQTAAEFGCPNCQDMLDMQGSQE-RVFTTSNFDGLICMLRP--EESWVAKWQRI-EKGLYAVKVGRLPETQ-------------- Mellp23 SKLRACMLCSFVQTAQQFGCPNCDDLLQMKGNSE-KVCTAGTFDGTAAILDP--DQSWVAKWQRI-NRGVYAIRIGSLPEHILEHR-G-RREDD-- Mnele NNIRACMMCSLLKNTEQFGCDNCDQWLSLKNNRE-RVCTSPNYEGMISLTNP--DESWVARWQGI-RGGMYAISVGKMPSHILERQ-GRRDLGIK- Monbr KHLRACLSCGLVKTSDQFGCENC-AYLDLNDNND-AICTTARFYGIVSVIDP--SDSWVAKWQGN-DAGCYALRLGHLPSDKMPPNLRLRELKMSN Morel2 KQLRACLLCSLIKKQEQFGCDNCESLLEMRGHMD-RVCTSQHYDGAIAVMQP--SESWVAKWQRI-DKGIYAVQVGRLPEEILEGK-GIRDGSARD Mucci2 KQLRACLLCSLIKNASQFGCENCEEILQMRGSMD-RVCTSGKFEGAIALMHP--KESWVGRWQRV-DKGVYAIVVGRVPEDVLDRR-GVRDGSVKD Mydma RHLRSCLLCSMVKTLEQFGCDNCERYLHLKGDHE-NTCTSANFNGIISMMTP--EDSWVAKWQRI-DKGCYATSVGKLPSDILKSR-GIRDTSSI- Neucr2 RYLRACMVCSIVMTYARFGCPNCEDFLHLQGSPD-QICTSQVFEGIITIANP--QKSWVAKWQRL-DGGVYATKVGQLPDDVLEDD-GIRDGSATE Orpsp11 ------------------------------------------------------------------------------------------------ Pench1 RTLRACMVCSVVQIHNKFGCPNCESTLQLRGNND-AICTSQVFEGLIAVRDP--AASWVARWQRL-DNGTYATKVGTLPEYILEDS-GIRDGSTGE Phybl2 KQLRACLVCSLVKNASQFGCDNCEDVLRMRKNID-RVCTSSKFEGMITMMNP--KESWVARWQRI-DTGLYAIRVGRIPEDVLERR-GIRDGSVKE Picst3 RSERACMLCGIVQPMKRFGCPNCESLLHFQDNEEGQVCTSPSFEGLVALGQD-NRNSWVARWLRI-DSGLYAVKVGKLPPHILEAQ-DVRDGSAED Plicr1 KGLRACLLCSIIQNPADFGCPNCEEIMQMKGSQD-RMCTTSYFDGIIAVVDP--ETSWVARWQRT-SKGMYAVRVGRVPEDVLEAR-GIRDQTDLD Polpo KSAKACTGCGLVKTQQQFGCENC------GGGRR-RATTTPNFEGVIAVLKP--NESWIARKQGL-DSGCYALNM----TDK-------------- Pucgr2 SKLRACMVCSFVQSAAQFGCPNCEEFLEMKGSVE-RVCTSGTFDGTVAMMNP--KESWVAKWQRI-SSGLYAIRIGSLPEHVLEHK-GLQRDDD-- Punst1 KSLRACLLCSLIQTPVDFGCPNCEELMQMRGSPD-RICTTTYFDGVIAVIDP--ETSWVAKWQRT-SKGMYAVRVGRVPEDVLEAR-GIRDGTEQD Rhior3 ----------------------------MRGSMD-RVCTSSKFEGCIAMMNP--KESWVGRWQRI-DKGIYAIRVGRIPEDVLARR-GIRDGSIND Rhoto1 KKLRACLMCSFLATPAEFGCPNCEDKLEMKGDAD-RVCTTGQFDGVIAAINP--EESWVAKWQRN-DKGVYAVRVGQLPDEILEGR-GIREMDD-- Rozal11 KRLRACLLCSL--TMAQFGCENCESLLMMKGNTD-RICTSQNFDGCTALMAP--GHSWV-------DKGIYALKVGRLPEDLLEDQ-GVEDD---- Sacce1 SSERACMLCGIVQTTNEFGCPNCQGIF-----EEAGVCTSPSFEGLVGMCKP--TKSWVAKWLSV-DHGMYAIKVGRLPAEVLPH----RDGSQVE Salro KKLRACIACGLVKTSQQFGCENCEEFLGLKGNPE-GVCTSGNFHGIIALIEP--GDSWVAR----------AKRLGSLADDALPEPIRQAEQQQAE Schco3 RHLRACMLCSLIQTSADFGCPNCDEVLQLRGSLD-RVYTTNQFEGVIAVIDP--EQSWVARWQRT-AKGMYAVRVGRIGQEMLEAR-GIRDGTDQD Schpo1 ---RACLICGIVLPHSVFGCPN-----DGVDDVE---FTSPVFEGIMAMMSP--TESWVARWQRI-DTGIYATRVGVLNEDVLRRR-GIRNGTSWD Sorma RYLRACMVCSIVMTYARFGCPNCEDFLHLQGSPD-QICTSQVFEGIITIANP--QRSWVAKWQRL-DGGVYATKVGQLPDDVLEDD-GIRDGSATE Sphar ------------------------------------------------------------------------------------------------ Spipu1 RHLRACLLCGLIKSAAQFGCENCDEVLHLKDHPK-RICTSASFDGIIAQMRP--EQSWVSRWQRT-DKGMYAIRIGRLPEEVLNDN-GIRDGSVRD Sporo1 KKLRACLMCSFVASATEFGCPNCEDRLEMKGDSD-RVCTTGQFDGTIALIHP--KESWVAKWQRN-SKGVYAVRVGQLPEEILEAR-GIREMDD-- Stehi1 KQLRACLLCSVIQTPSDFGCPNCEEIMQMKGSPD-RICTTTYFDGIISVIDP--ETSWVARWQRT-SKGMYAVRVGRVPEDVLESR-GIRDQTDQD Tapde11 KNLRACLMCAILLTSDQFGCPNCESILRTSERPE---VTSPNHEGRIAMMSP--SDSWVAKWQRS-SNGLYATRVGRLADEILEAQ-GIRDGSYVE Thetr KELRACRSCLLVKNRGQFGCENCGE----------EVLTTTSFSGLIAVMDNDTSKSWVSRYQRL-GEGMYAIKITRPAEDTGAAR---DDEEDPE Treme1 ADSRACLVCGILQTPNEFGCPNCEEILNLKGNAD-RVCTSALYDGVIAMMQP--EESWVAKWQRI-DKGLYAVRVGRPPQDVIEER-GGRDTVED- Trire2 RYLRACMVCSIVMTYSRFGCPNCEEFLHLIGSQD-QICTSQVFEGLISLANP--AKSWVAKWQRL-DGGLYAIKVGQLPDEILEDEYRIRDGTQTE Umbra1 KQLRACLLCSLVKNASQFGCENCEDIMRMQGSVE-RVCTSANFDGVIAMMRP--DESWVGKWQRI-DKGIYAVRVGRIPDDVLDRR-GIRDGSARD Ustma22 EKLRACLRCQFVQSPRDFGCPNCEPVLEMQGSQD-RVCTTSNFDGMISMLRP--EESWVAKWQRI-EKGLYAVKVGRLPEGI-------------- Walse1 SKFRACLMCSYLQEGKEFGCPNC-PFLEMKGSSE-SVCTSGQYDGIVALTQP--KGSWVGKWQRV-NTGLYAVRVGRLADNILQAH-GIRDEIEE- Zygro1 SSDRACMLCGIVQTTNEFGCPNCQGIF-----EEAGVCTSPSFEGLIGMCKP--NKSWVAKWMSV-DQGMYAVKVGRLPIEVLPY----RDGSQVE [Cluster2219.fasta_al_trimmed; alignment length = 95] Allma1 PKAAAAPEDLRAQEELEGPLSVLRTAVKNNNQILINCRNNRKLLARVKAFDRHCNMVLENVKEVWTEIPKRKPVTKDRFISKMFLRGDSVIL-VV Ashgo11 PRSELTQDELAQLEEFEGPMSLIQEAMTARTPVIISLRNNHKIIARVKSFDRHCNMVLENVKEIWSE---I--SNKERFISKLFLRGDSVIV-VL Aspfu1 PKSELTEYEVALVEEHEGPLSLLQTATRTHTQVLISCRNNRKLLARVKAFDRHCNMVLENVKEMWTEKPKGRGVNKDRFISKMFLRGDSVIL-VL Aurde31 PRSELDEAQLRQLEEHEGPLSVLQQAVRNHTQVLISLRNNKKLLARVKAFDRHTNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVVL-VL Batde5 SKSEMSEIELQALEEAEGPLSILTQAVKNSSQVLVVCRNNRKLLARVKAFDRHCNMVLENVKEMWTETPQAKPVNKDRFISKMFLRGDSVIL-VL Botbo1 PRSELDEAQLRQLEEHEGPLSVLQQSVRNHTQILISLRNNKKLLARVKAFDRHCNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVIL-IL Botci1 PRNELTEFEVAQIEEHEGPLSLLQAAVRSHGQVLISCRNNRKLLARVKAFDRHCNMVLENVKEMWTETPRGRPVNKDRFISKILWRKQM------ Caeel PRSEMTAEELAAKEDEEGPLSILTNSVKNNHQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKAKSVAKDRFISKMFLRGDSVIL-VV Canalb1 PRSELTELELKTLEEYEGPMSILNNAVKNDSPIIISCRNNHKLIGKVRAFDRHCNLVLENVKELWTEDIKIKSISKERFISKMFLRGDSVII-IL Cangl PKSELSKEELEQLEEFEGPMSLINDAMITRNPVIISLRNNHKLIARVKAFDRHCNLVLENVKELWTE---T--INRERFISKLFLRGDSVIV-IL Capow DKSQMSEAELAQHEKEEGPLSVLTKAVRSNAQVFINCRNNRKLLARVKAFDRHFNMILEDVREFWTEGTRSKPVNKDRFISKLFLRGDSVII-IL Catan2 ----MTAEEARAAEELAGPLSVLRAAVKNNNQILISCRNNRKLLARVKAFDRHCNMVLENVREIWTEYPKAAGVQKDRFISKMFLRGDSVII-VV Cioin PKSELTAEELEALEKEEGPLSVLTDSVKNNTQVLINCRNNRKLLARVKAFDRHCNMVLENVKEMWTETPKQQPVNRDRFISKMFLRGDSVII-VL CocheC53 PRSELTEYEVAQVEEHEGPLSILQTAVRSRTQVLISCRNNRKILARVKAFDRHCNMVLENAKEMWTETPRGRKVNKDRFISKLFLRGDSVIL-VL Coere1 SKGDMTHEELTLLEEKEGPLSVLQMAVNNNTQILISLRNNHKLLARIKAFDRHCNMVLENVKEMWTETPKAAPINKDRFISKMFLRGDSVVV-VL Conco1 ----------------------------------------------------------------------------------------------- Conpu1 PKSELDEGQLRQLEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVIL-IL Copci PKSELDEAQLRQLEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTETPKKKPVNKDRFISKMFLR-------YL Croqu1 PKSELDEEKIRALEEHEGPLSVLQSSVKNHTQILIALRNNRKLLARVKAFDRHSNMVLVNVKEMWTELPKKKPVNKDRFISKMFLRGDSVIL-VL CryneH991 PKSELDEAQIRELEEYEGPLSVLQQSVRNSSQVLISLRNNKKLLARVKAFDRHCNMVLENVKEMWTETPKKKPVNKDRFISKMFLRGDSVIL-VL Crypa2 PRNELTEYEISQLEEHEGPLSILQTAVRSHTQVLISIRNNRKLLARVKAFDRHCNMVLENVKEMWTETPKGRPINKDRFISKMLLRGDSVIL-VL Debha1 PRSELTELELQKLEEFEGPMSLLQNAVNNGSPVVISCRNNHKLIAKVKAFDRHCNLILENVKELWTESVKIKSTSKERFVSKMFLRGDSVVI-VL Dekbr2 PKSEMSEKELQELEQYEGPMRLLSKAVKDSSTILISLRNNHKLIAKVKAFDRHCNMILENVREFWNETAPKRKIVRERFVLKMFLRGDSVIV-IL Dicdi -MSRMNDETME--DKPDGPLSILMDSVNNNTQVLINVRNNKKLLGRVRAFDRHCNMVLENVKEIWTEVPKAKPINKDRFISKMFLRGDSVIL-VL Dmel PKSELTPEELARQEEEEGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTELPRVKPVNKDRFISKMFLRGDSVIL-VL Enthi -----MEEETKALVE--GPFQLLTEAVEKHGQVLINCRNNKKLICRVKAFDRHFNMVLENIKEIWTEMKRAKLCQRS--ISKMFLRGDSVIV-IV Falba SKNEMSEIELRRLEEEAGPMSILLEAVKNQSQVFISCRNNRKILARVRAFDRHCNMVLENAREIWSEMPKPKPINRDRFITKMFLRGDSVIL-IL Fomme1 PKSELNEAEIRQLEEQEGPLSVLLQAVRNHHQVLISLRNNKKLLARVKAFDRHTNMVLENVKEMWVEVPKKKPVNKDRFISKMFLRGDSVIL-IL Fusgr1 PRSDLTEYEIAQLEEYEGPLSILQTAVRSHVQVLISIRNNRKLLARVKAFDRHCNMVLENVKEMWTETPRGRPVNKDRFISKMFLRGDSVIL-VL Galma1 PKSELDEAQLRQLEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEIPKKKPVNKDRFISKMFLRGDSVIL-IL Ganpr1 PKSEMTEEELRKIEDEEGPLSLLTNAVRANAQVLVSCRNNRKLLGRIKAFDRHMNMVLENVKEMWTETPKAKPINKDRFISKMFLRGDSVIL-CL Gloin1 SKAEMTEEELRQLEEHEGPLSVLQQSVKNNTQILINCRNNRKLLARVKAFDRHCNMVLENVKEMWTETPKAKPVNKDRFISKMFLRGDSVIL-VL Hisca1 ------EYEVSILEEHEGPLSILQTATRSHAQVLISCRNNRKLLARVKAFDRHCNMVLENVKEMWTEKPKGKGVNKDRFVSKMFLRGDSVIL-VL Klula1 SRSELSRDELTQLEEFEGPMSLIRESMLQRTPVIISLRNNHKLIARVKSFDKHCNMVLENVKEIWTEN--GKKVNRERFVAKLFLRGDSVII-VV Lacbi2 PKSELDEAQLRQLEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVIL-IL Lenti61 PKSELDEAQLRALEEHEGPLSVLQQAVRNHTQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEMPKKKPVNKDRFISKMFLRGDSVIL-VL Malgl1 PKSDLDEGQIRELEQYEGPLSVLQQSVRNHSQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEVPF---VARQR-CNELLPSNDSIGYN-- Mellp23 PKSELDEEKIRALEEHEGPLSVLQSSVKNHTQILIALRNNRKLLARVKAFDRHSNMVLVNVKEMWTELPKKKPVNKDRFISKMFLRGDSVIL-VL Mnele ----------------------------------------------------------------------------------------------- Monbr ARGEMPQEELEKIEQQEGPMSVLTQSVKSNTQVLIFCRNNKKLLARVKAFDRHCNMVLEQVKEMWTETPKKKPINKDRFISKMFLRGDTVIL-VL Morel2 PKSEMNEDELRKLEEEEGPLSVLQLSVKNHTQILISCRNNRKLLARVKAFDRHCNMVLENVKEMWTEVPRAKPVNKERFISKLFLRGDSVIL-VL Mucci2 PRSEMTEEELRQQEELEGPLSVLQQSVKNNNQILISCRNNHKLLARVKAFDRHCNMVLENVKEMWTETPRAKPVNKDRFVSKMFLRGDTVVL-VL Mydma PKSELTFEELKQREEEEGPLSVLMTSVKNNTQVLINCRNNRKLLGRVKAFDRHCNMVLENVKEMWYEIPKAKPINKDRYIAKMFLRGDSVIL-VL Neucr2 PRNELTEYEVSLLEEHEGPLSILQTAVRSHSQVLISVRNGRKILARVKAFDRHMNMVLENVKEMWTETPRGKPVNKDRFISKMFLRGDSVIL-VL Orpsp11 PKSEMTEEELRKIEEEEGPLSVLSQSVKNNTQILISCRNNKKLLARVKAFDRHMNMVLENVKE-------------------------------- Pench1 PKSELTEYEVALVEEHEGPLSLLQTATRTHTQVLISCRNNRKLLARVKAFDRHCNMVLENVKEMWTEKPKGKGVNKDRFISKMFLRGDSVIL-IL Phybl2 LRSEMTEEELRQQEEIEGPLSVLQQSVKNNNQILISCRNNHKLLARVKAFDRHCNMVLENVKEMWSETPRAKPVTKDRFVSKMFLRGDTVVL-VL Picst3 PRSELTELELQKLEEFEGPMSLIQNAVNNNTPIVISCRNNHKLIGKVRAFDRHCNLILENVKELWTETSKTKSISRERFISKLFLRGDSIVI-IL Plicr1 PKSELDEAQLRQLEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTETPKKKPVNKDRFISKMFLRGDSVIL-IL Polpo ----------------------------------------------------------------------------------------------- Pucgr2 PKSELDEEKIRALEEHEGPLSVLQSSVKNHTQILIALRNNRKLLARVKAFDRHSNMVLVNVKEMWTELPKKKPVNKDRFISKMFLRGDSVIL-VL Punst1 PKSELDEAQLRALEEHEGPLSVLQQAVRNHAQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVIL-VL Rhior3 PKSEMTEEELRQQEELEGPLSVLQQSVKNNNQILISCRNNHKLLARVKAFDRHCNMVLENVKEMWTETPRAKPVNKDRFVSKMFLRGDTVVL-VL Rhoto1 NKSEMDEAQIRALEEHEGPLSVLQTAVRSGSQVLVALRNNRKLLGKVKAFDRHSNMVLENVKEMWTEAPKRKPVNKDRFISKMFLRGDSVVL-VL Rozal11 YKSEMTPEELKALEEEEGPLAALTHAVKTHNQVLISCRNNRKLLARVKAFDRHCNMVLEHVKEMWTENPKAKPVNRDRYISKMFLRGDSVIL-VV Sacce1 PKHELSRAELEELEEFEGPMSLINDAMVTRTPVIISLRNNHKIIARVKAFDRHCNMVLENVKELWTE---V--INRERFISKLFLRGDSVIV-VL Salro ----------------------------------------------------------------------------------------------- Schco3 PKSELDEAQLRQLEEHEGPLSVLQQAVRNHTQVLISLRNDKKLLARVKAFDRHSNMVLENVKEMWTEIPKKKPVNKDRFISKMFLRGDSVIL-IL Schpo1 PRSELSEIELARLEEYEGPLSVLQQAVKNHDQVLINCRNNKKLLARVKAFDRHSNMVLENVKEMWTEKKRGKAINKDRFISKMFLRGDGVVL-VV Sorma ------EYEVSLLEEHEGPLSILQTAVRSHSQVLISVRNGRKILARVKAFDRHMNMVLENVKEMWTETPRGKPVNKDRFISKMFLRGDSVIL-VL Sphar ----MSALELKEIEENEGPLSVLTQAV------LINCRHNRKLLGRVKAFDRHCNMVLEDVKEMWTEVPKARPVNKDRFISKLFLRGDSVIL-VL Spipu1 AKSEMTEAELAAQEEAEGPLSVLTQSVKNNSQILIMCRNNRKLLARVKAFDRHCNMVLENVKEMWTETPKAKPINKDRFISKMFLRGDSVVL-VL Sporo1 NRSEMDEAQIRAIEEHQGPLSVLQTAVRSNTQVLIALRNNRKLLGKVKAFDRHANMVLENVKEMWTEAAKRNPVNKDRFVSKMFLRGDSVVL-GT Stehi1 PKSELDEAQLRQLEEHEGPLSVLQQAVRNHTQVLISLRNNKKLLARVKAFDRHSNMVLENVKEMWTEIPKKKPVNKDRFISKMFLRGDSVIL-IL Tapde11 ----------------------------------------------------------------------------------------------- Thetr --MELEQPEVP--KEGEGPLSMLADAVKNSTQVLIALRNNRKLLARVRAFDRHFNMVLENVSVFWTEKGGAEDVEKDMFVSKMFLRGAGVVL-VL Treme1 PKSELDEAQLRELEEYEGPLSVLQQAVRNQSQVLISLRNNKKLLARVKAFDRHANMVLENVKEMWTETPKKKTINKDRFISKLFLRGDSVILGVL Trire2 SRSELTEYEIAQLEEYEGPLSILQTAVRSHTQVLISIRSNRKLLARVKAFDRHCNMVLENVKEMWTETPRGRPVNKDRFISKMFLRGDSVIL-VL Umbra1 PKSEMSEAELREIEEQEGPLSVLQQAVKNNSQVLINCRNNRKLLARVKAFDRHCNMVLENVKEMWTEVPKAKPVNKDRFISKMFLRGDTVIL-VL Ustma22 PKSELDQSQIRELEQYEGPLSVLQQSVRNHTQILIALRNNKKLLARVKAFDRHSNMVLENVKEMWTEVPKKKPVNKDRFISKMFLRGDSVVL-VL Walse1 PKSELNEEQIRQLEEFEGPLSVLQQSVKNNTQILVSLRNNRKLLARVKAFDRHSNMVLENVKEMWTETPKKQPINKDRFISKMFLRGDSVIL-VL Zygro1 PKSELTAEELEQLEEFEGPLSLINDSVTTKNPVIISLRNNHKIIARVKAFDRHCNMILENVKELWTE---V--VNKERFISKLFLRGDSVIV-IL [Cluster2222.fasta_al_trimmed; alignment length = 180] Allma1 DW-NSLRRSARQVELAKFSAMAAIERDIADLLRQLANHVDRLSAPPASFH-LAQRHRDTLQDLTREFRRIKSNLVAAREHAELLESVRSD-IKA--NYLATERMRLDSTHIMVDDLIEQAQETHSDLTAQRELLLGANRRMGGVNGVFPQLMSLMTRIRIRKRRDTIILSGVTACIFLLY Ashgo11 SF-VTVRGKAISLELSRYSSYAQLAEKLESVLKERQGVIEELQSS-KLSQ--LQRHREVLQQHWQTFQSIRSSIQQERSRLNLLFSVKRT-LEQSEQYAAAETRRIEESHNVLDRLISQAFETRDRFAEQRFSLQRANDRVYQTLQRIPGINHVLSQITIRRRKNAMILALTMTCIVLLY Aspfu1 GW-AQLRQQARSLEFHTYAQYASIESQLKDLLEKREALISQLSAS-ALKQSNLARNREVLQDHRRELQRLNAAIAESRDRANLLSNVRSD-IDAYRDYMLEERGRIDESHNMIDGVLSQAYAINESFGLQRETLASINRRIVGAANKVPGMNALIGKIGTKRRRDAIILGAFIGCFLMVF Aurde31 TF-ETLRRQSRTLELNAYSRHATMEEEIDGLLEKLRETTDELASP-TQTH-ALQRHREVLQDYTRDFGRIKANVQQARDRANLLQNVRSD-INAYKDALLTERGHIDSSHRMADDLLGQAYATRDEFASQRSTIAGINTRMAGVMTQFPGLNSLVSMIRSRRRRDSIILGLVIGCTILLL Batde5 TW-DSLRKHARQLELVSFSKVASIEQDLDNLLNQLTTTINSMSSRASMTH-LLHRHRSNQFEYSKEFRKTRTNILAKKEHAELLSSIHND-INPHRDYYLSERERLEQTNTMADDIFQNAMDAHDDLGRQRSSLFGSHGRIAGILNRFPQLNNTLSRINSRKFRDTWIMGVVLGGMCVLL Botbo1 KL-ESLRRQCRTLELTTYSRLASIEHEIEGLLEKLRDTNEEMATQ-SSLH-AIQRHRDILQDYARDFAQTRVNAKSALDRANLLTTVRND-IDAYKDSLLAERGRIDSSHRMTDDILEQAYETRAEFSRQRSTLGTINARMGQVLGTFPGINNLVSMISSRRRRDSLILGCVIGCIIVLL Botci1 GW-AQLRQQARSLEFHTYSQFSATEMKLQEILEKLENLISQLSAS-ATRQNNLTRHREILLDHRRELSRIRSSISEARNRANLLSNVRSD-IDAYHDYMLGERSRIENSHNMTDSF----WATEGN------------------AGQY-------------------------------- Caeel TW-EALRKKARSTELVSLNKLTAVTTEIEGLIEQLTNINDDMNNNPAIQH-TLRRHREILRDYGSEYRRARDNVDQVLQRELLLSSSRNNPILNNRDMYLKENDHINACDRLLDEQLEMAMSTKENMARQGINLRGISTRLHHISKKYPAINNLMQKIKTKKQKNTLILAAVISCLIFTI Canalb1 TF-SQTRSQALSLELSKFSQFQQIRQQIEEIFQKRNAVISKLNTS-KLQQ--LTRHKEKLNDDNLSFTKIINNIEDERNKNNLLFNVHRD-INHHKAYILEESERVNNVNSIADRLLQGAFATRDELLNQRQYLNNAQSQVLSTMQNIPGLNVLISKINTRRKRDTLILASVIACILFLF Cangl SF-VTVRSEAISRELGKYSTYAQLDEQIEKLLGERQDIIDNLTAS-KQSQ--LQRHREILQEHWKNFRGIRSSIQQERNRLNLLFSVKND-IAQQQAYNQNESRRIDQSHNILDRLIVQAWETRENFNAQSSTLNSAGNKALQTLQRIPGVNLLIGKIGTRRRKNAIILASVTTCILFLF Capow NWAEELRREARQLELVSFGKLAAMAIELEQLLVKLSNVNEAMTNP-ALVH-TLQRHRDILTDYTQEFRKTKSTLLANRERDDLLNSVRRD-ISSFKDYFAKENEHLMNSQRVADDAIGIAINAKESMAQQRSTFQNINNRMGNVFNRFPQLNNLMQKINLRKRRDAIILGLVIACLIFLL Catan2 DW-DSLRRMAKQMELASFARHA-TEAHLEDLLRRLALVVEQMASSPSSWHLLLQRQRDTLMEHTREFRRIKANLIAAREHSELLNSVQSD-IHAHKDYFLTERNKLDSTHIMIDDIIDQAHETRTNLDAQRETLLGAHRRITGLHTVFPQLTGLMTRIRLRRRRDTIILSLVTACMFLLF Cioin -----------------------MAMEIEQLLMKLTGMNDSMSSS-AMLH-TIQRHRDILQDYTHEFRKTKNNIHTFREREDLLGSVRRD-IDAYKNVY--------------------------EGARPLKKF---------------------------------------------- CocheC53 GW-AQLRQQARTLEFHTYSQFGSVETRLQEILEQRDALVAQLSSS-AVKQNNLARHREVLSDHRRELARLKSSLNDARNRANLLSNVRSD-IDAYRDYMLDERNRIDNSHNMADSVLSQAYAVQENFAIQRETLANINRRIVGAASQVPGINSLMGRIGSKKRRDGIILASFIACFLMLL Coere1 PW-EQLLRDVRDLEIAQYMQFVRLETEIKTILEDLDAVISEMN---GSTR-VLERHKSMYNDYLREFQRYQANVQAALARTELLGNGAEN------DRLVDERMRIDQTHTDIDMVLDQAFSVRQDLAEQRTIISSATAKMVNVTERIPGVNMLLGRIRSRKRREKVVLAIVLACISILL Conco1 NW-DQLTKDAKKLQLRNVLNLSQISLEANANIEKLQNIVDQLNTA-LMLR-GLQRHRDILFDLLKEQKKVQMNLNSSRNRQQLLKNADSE------QYYLNEQQRLDSSYQMTEDVLNQAYAIHSDLHDQRNTITGVSRRLSKVTNMIPGLNGLLSKISHKQQKDTIILGTVIAGIIFLF Conpu1 TY-DSLHRQCRTLELTAYSRLASLEGEVEDLLEKLKESNDELSSQ-TMSR-AMQRHREVFQDYSKEFRRTKANVQTALDQANLLTGVRND-IDAYKDSLLAERGRIDSSHRMTDDLLDQAYETRAEFSRQRMSLGGINARMGQVMNTMPGINSLLSMIKTRRRRDALIIGVVIACLILLF Copci NY-DQLHRQCRTLELTSYSQLASLEVELDDLSTKLQEINDELGSA-SMLR-TIQRHRELHQDNVRELRRTKANVKAAFDQANLLSGVRND-IDAYKDSLLEERSRIDSSHRMTDDLLDQAYETRSEFARQRMSLQGINSRMLHVINTMPGVNNLIAMIKSRRRRDSIIMGVLIGCTIILL Croqu1 GR-HSVVRSVRTLEITTYAKLCTVEGQIEDGLKQLSLLVDQMLTS-SMQH-ASTRHKEILADYERDFIRTRTSLREAEQRASLLSSVRSE-ISSFKDRHLADRDRINTSHRLADDVLNQAYETRYEFSRQRNSIMGSNTRMGGVIASIPGVNSLVGMINSRRRRDTMILATVAGCTFLLL CryneH991 SW-DNARRHARALELSSYSKLAAVEEEIEELLSKLEQAIEDLTST-SMQH-SAQTHRDNLDDYKRDFVRTRNNVEQTIRRSNLLGSVRKD-ISDYKDALLQDRSRIDSSHRMIDDTLNQAYATREDFAQQRTFLASIDSRMGGVLNQMPGINSLITMIRTRRRRDTVIMGCVIGCVVLLL Crypa2 GW-AQMRQQARTLEFHTYSQFSTTEAKLQEILEKRENVINQLASS-ALKQNNLALLREKLASHKRDLVRLRSNLADARGRANLLSNVRED-IQSFREYMLDERRHIDNSNSVADSVLSQAYAVQESFVLQRETLANINRRITLAASQVPGINTLIGRISARKQRDGIIMGSFVACFLLFW Debha1 TF-TQTRSQALNLELSRYSAFQNLSDSIFENLQKRENVINTLNTS-KLQQ--LQRHKEILSEHKRSYAKIKGVIKEERNRNNLLFSVRSD-IDAHRDYILDESVRADNANSFAERLLQQAYNTRDELYSQRAHLSNAQLRMMGAVLLIPGINVLISRINTRRKRDTLILATVIACILVLF Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi -W-DQLKKERRRLELNHLSTLNDLSSELDSAFKNLQRCNDMLV--------KV--HKDKLDDYLNEYRRLKKNIKSTLESFELLEGSNKD------TSLLREHSTLQSSSYVQDSILGQARQAHEALENQRRILRGTSHKINTMPSLFQTIDGVTSKIKRYKQRNVVVLGLLIGLICFLF Dmel SY-DVLRKQARSLELVAFSKIGALSEEIEQMLEKLSSLNESMS---AAMH-TLQRHREILQGYRQEFNKICANHTMRIEREELLRGSGLA-TSSGSEMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGCVILLL Enthi --------------------------KQQELLWEER-------------------------------------------------------------------DSINRSSQLADILIDQAFEDNASIDRQNQAMAKINNRNSVYNSTLNDSNRLTNRISWHQCKNTIILACVCACIFFLI Falba NW-DSLLQEARRVEINAYNSLARIPVKIQQYLAELRRIVESMETA-STVAVFLRRYRESVAKYEMIYRRNLDRVLAKSKRTGLLAGTAGQ------GLLVTGLNHLDQSNQQALDLLDQAHEAHEALITQREMLNRAHGRVANINSRLPRINALLKKIKRRKKRETLILGAVAGCLFLVV Fomme1 TY-DNLRKQCRTLELTSYSRLAALEEEVDGLLEKLRETNDQLGSQ-SMVW-AIKRHREVLNDYERDSARTKTNVKAALDRANLLSGVRND-IDAYKESLLTERGHIDNSHQMADDILSQAYETRAEISSQGRSLGGISTRMTGVLSTMPGINNLLAMIKSRRRRDSIILGCVIGCVLFIV Fusgr1 SW-TSLIQQARQLEFHTYSQFAATEKKLEELLEKREDVISKLVSS-AMKQNNLALFQKKLASHRKDLIRLRSNLQEARNRANLLTNVRSD-IDQYRDYMLQERNRIDNSNSMADNVLSQAYAVNDNFNLQRETLASINRRITHAASQVPGINTLIGRISAKKRRDGIIMGGFVACFIVFF Galma1 NY-DQLHRQCRTLELTSYSQLVSLELELDDLSSKLEEINEQLSSA-SMLR-AVQRHRELQQDNLRELKRTKTNVKHAMDQANLLSGVRND-IDAYKDSLLAERGRIDSSHQMTDTVIQQAYETRSEFGRQRASLAGINNRMVQVIGTMPGINNLVSMIKSRRRRDSIIMGVLVGCIIILL Ganpr1 SW-DVLRRQARQLELSQFSRLAALERELEEKLEKLTFIVSGMGSPAANLH-ALNRHRDILHEFSKEFSRSRQTARTARERVQLL---RSQ-LAEYGDYLLTERGRIEGVGSAADDVVRWAEEAKDDLGKQRGVLGGVERRAGGIVSRFPALNSLISNISTKRRQDALVLSGLVGLTFLLL Gloin1 SW-EYLRKQARQFELTSYSKIAAMELELEELIKKLTSVVNSMANP-SMMH-MLQRHRDILYDYSKEFKKTKANILAAKNHSDLLNSVRED-ISSFKDYFLGERGRIESSHRMTDMIIEQAYETREEIGRQRNILLNMNNRMNRLTNMFPGINSLIGRINLRKKRDTIILAFIISCI-ILI Hisca1 GW-AQLRQQARSLEFHTYAQYASAESQIHEILERREAIISQLASS-ALKQNNLSRHREILRDHRRELKRLNSAIAETRDRANLLSNVRSD-INAYREYMLEERGHLENSHNMMDSVLSQAYAVNENFGLQRESLARINRRIVGAASQVPGMNSLIHKIGAKRRRDGIILGVFIGCFLMVF Klula1 SF-VTVRSKAISLELTKYSSFAQLQEKLEKILNQRQETVESLQTS-KLSQ--LQRHRETLQDNWQTFRDIRSSIQQERNRLNLLFSVKKD-LQNSAEYIQDEARRVENSHTVVDSLIDQAYETREQFMSQRVFLQRSSDRILQTLQHIPLINNVISKINTRRKKNAVILASLISCILVLF Lacbi2 NY-DELHRQCRTLELTSYAQVASLEAELDDLSLKLQEINDQLASP-SILR-AIQRHRELQQDHLRELRRTKANVQTALDQANLLSGVRND-IDAYKDSLLAERGRIDSSHRMTDDMLQQAYETRSEFSRQRSSLTSIQGRMLHVINTMPGINNLVSMIKSRRRRDSIILGVVIGGFIIIL Lenti61 TY-ESLHRQCRTLELTAYARLASLEIEVDELLEKLQEINDQLSSQ-SMLR-AIQRHKEVYLDYARELRRTKGNVKTALDQANLLSGVRND-IDAYKDSLLAERGRIDSSHRMTDDMIAQAYETRAEFGRQRTTISGINARMQGVLSSIPGINNLLSMIKTRRRRDAVIVGCVIGCTVLLL Malgl1 TW-EVQSRRARQTQLTTYSQYVSMETDIQSLLVQYSEEIDELSNT-TQLH-LVQRHRELLVEFEREFFRSKTHVRQTLDRQQLLGHVKQD-IRYVS----------------------------------------IVRLHTHVATTGPSM---------RQKSSHF------------- Mellp23 -----MWMSVRTLEITTYAKLCTIESQIEDNLKQLSLLVDQIFTN-SMLH-TTNRHKEILETYEKDFKRTQSSLRSSEQRASLLSSVRHE-ISSFKAHHLADRDRIHSSHRLADEILDQAFATRQEFSVQRNSIFGSNHRMNRVMSSIPGMNSIVGMIQSRRRRDTLILALVAGCTFLLL Mnele GW---------------------MSVEIESILGNLTSVNDEMATA-SMRH-ICQRHRDILQDYTQEYCKTKSNIQAFKDREELLGSVHQ--VNSFKDFFLKENENIMGADGITNDAISIAMATKENLYTQRGGLAGITNKMNAISNKFPMIGSLMNKINVRSRRDSIIIAGVITCLIALF Monbr TW-EGLRRQARELELMSYSKYGALEQELQGLLEELTVVNDSLA--ATMLH-TVDRHRDILMDYSKEFHKTQANNRHQRERGELLTSVRNN-IRDYKELYMQESDHIASSTRIADDTVSLAMSAREALLEQRNVLQGAGSKLLSTMQRLPLINNLSQRISMKKKKDTVILATVIACIIFSI Morel2 SW-DTLRKEVRQIELTALSKLAVLEANIEELLEKLSRTVDAMSAPLSMTH-LLQKHRDILHDYTKEYRKTRQNVRAARDHAQLLTSVRDD-ISSFKDYLLNERSRIDGSHSLADSALEQAYATRDDLDRQRSTLLSVNQRINNVATQLPSVGQLIGKIQSRKNRDNVILSCVIGCVVGVL Mucci2 SW-DQLRKEARTLELAVLTKIGQQEAETEDLLKKLQAVIAGMGNP-SMIH-LLSRHKDILYDYTKEFRRVKSNIKQARDKANLMNQVQDE-IRTFNDYYLTERNRIESSHRMTDMVLEQAYATRQDVSRQGRIMHGVNQRVGGIVNRIPGINNIISRINTRRKRDTLIMAGVVSCTILII Mydma NW-EDLRKQARQIELVSFSKLGTMSLEIERLLLRLTEINDDMSNG-AQLH-TMQRHRDILQDYSHEFIKTKANIKASKDREDLLGSVKKD-ISEYKDLYLKENDHIRNSDRLADEAIDIAMSTKENLASQRKMFHSMSNRILSLGNRFPQINSLFQKINMRKKRDTIIIAIVISCLIILL Neucr2 GW-AQLRQQARSLELHTYAQFSNTETRLRELLDKRESVISHLTPS-ALKQNNLSLLRDKLSDHRRDLSRLRSTLESARTRANLLGSVRDD-ISAYRDYMLDERGRLDRSHDVADSVLSQAYAVQDSFASQRERLAHINRRITLAASQVPGINTLITRISARKRRDGIIMGSFIACFLMFW Orpsp11 SW-EELNRKARMLEIITFSKLVSLDRDIDSTLMKLQNVIDNMANN-SMIH-FLQRHRDMFYDYSKDYKKYKNNYVQTNEYNELMNSMKNE-VRTFKEYLLNERGRIDESNRMADMVLEQAYSARNSLLEQRSMLHGTSSRMSNITTRFPIINNLIGKISRKKRRNTLILSSVTA------ Pench1 GW-TQLRQQARSLEFHTYSQFASLESQLKDLLERRESVIAQLSSS-ALKQNNVSRHREVLQDHRRELQRLTAAISESRDRANLLSNVRSD-ISSYREYMLEERGRVENSHSMMDGVLSQAYAINENFGVQSETIANINRRIVGAAGNVPGMNYLIGKIGNKKRRDAIILGCFIGCFLMLL Phybl2 SW-DQLRKEARQLELASLAKAGAQELEIEALLTKLQSVISAMTTP-SMIH-LLDRHRDILYDTTKEFRKVKSQLKAARDKADLMNQVRDE-IRSANDYYLTERNRVESSHRMTDTIIEQAYATRQDISRQGRTIHQVNTRVGGIIGRLPGINNIISRINTRRKRDTLIMAGVISCIILIT Picst3 TF-SQTRSQALSLELARYSNFQNIFTSIQETLEKRDATLAKLNTS-KLQQ--LTRHKEILSDHKASFNKIAANIEEERNRNNLLFSVRSD-INAHRDYVLEERQRVDNANTFADRLLNLAYQTRDELYNQRQYLNNAQLKMFSTLQQIPGINVLISKINTRRKRDTFILATVIACILLLF Plicr1 SY-DDLHRQCRTLELTAYARLASLEIEVEELLEKLEETNERLTSQ-SMLR-AVQRHHDVVADYAREFRRTKAGVQAARDRENLLSGVRND-IDAYKDSLLAERGRIDSSHRMTDDILEQAYETRSEFARQRSSLAGINTRMQGVLNQMPGMNKLVSMIKSRRRRDTVIVAVLIGCTLFIL Polpo TW-DSIRKEIRKYELSALSSLNDLTSELDSIFKNLTRCNELLA--------MIQHHRDKLEDFLKDYKKYKKNITYSLEHSELLSGSNKD------NNLLREQQSLHNSNYVADSILGQARQAHEALENQRKILRGASHKINNMTGIFGAIDGVTTKIKRMKSRNMMVLGGLIGIGCFLL Pucgr2 SW-ETLRRQIRSLEITTYAKLCTVEERIEDNLKQLSLQVDQIYTG-SMTH-ACNRHKEVLQEYERDFKRTRTSLRECEQRASLLSSVRSE-ISSFKDRHLNDRSSINSSHRLADDVLGQAYETRYQFSNQRRTLFNSNSRMGSVIATVPGVNSLISMINSRRRRDTLILATVAGCTFMLL Punst1 GY-DALHRQCRTLELTTYTRLASVESEVEDLLEKLRETNEQLSSQ-SMIR-AIQRHRDVFRDYQAEFKRTQANVRNALDRANLLSGVRND-IDAYKDSLLAERSRIDSSHRMTDDILEQAYTTRAEFSSQSVSISSINARMQNVISTMPGINNLLSMIKSRRRRDAIIMGLVIGCTILLL Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 -M-ETLRRDLHASTLTRYSKLAALEEELTGALDTFSAQIDRLASA-SATH-ALERHRDVLAEYRRDFQRTQASLRDAEQRANLLGSVRQE-ISAFKDSLLAERGRIDNSHRMADETLEQAYATRAEFSAQRSNLSRIQQRMNGVASQVPGLNSVIGMINNRRQKNAMIWGVVLGMAVILL Rozal11 SW-DSIRKETRMVEISKITSLMALAQEIISNLSNLNNQIAKMNNT-ILLK-TLQRHKDGAFNYEKEFRRIQDVLRQKKEEQELLKSYK-------------------------------------------------------------------------------------------- Sacce1 SF-VTIRGKAISLELSKYSTFAQIDKQLEGILGQRQDVIDSLTAS-KLSQ--LHRHKEILQDHWKSFRNIRSSIQQERNRLNLLFSVKND-IANS-EYIQNETRRIDQSNNVVDRLISQAWETRSQFHSQSNVLNTANNKVLQTLQRIPGVNQLIMKINTRRKKNAFVLATITTCILFLF Salro PW-EAKHLRVRQLELRNFNQLKRVYAEIQNCLDEFSVLTSEMVNQLAQKE----------TAYHRQFARIKQSIKAQMEKEDLLDNVKKT-INDHHDLYLKESDHIRTSDRLTDDILGMAAGARNALQDQASRIDNVFSKLSTTMNKFPVINQLSKNIDLRKKRSAIILGSVIACVVFSL Schco3 SY-DALHRQCRTLELTSYAQLASLEMELEELLEKLEDNNAQLASP-SMQR-AVQRHQELCRDYARDLRRTRANVQAARDQANLLSGVRND-IQAYKDSLLEERGRIDSSHRMTDDLIAQAYETRADFSRQRASLVGISSRMQGVISQMPGINQVIGMIKSRRRRDAIILGVVIGCFIGLV Schpo1 ---DS--KKASQFQ---------LLEERRKLLEE---------ADENDSH---------------SMATIKSHFERLKRDEQLLNGVKQEVLSPEEFLEMQEANSLDNSIRGTNELLERAYATREDFDYQNSVLGNVTNRINGAAMSIPFINQILRKTSIRRRRDSIILALLISLMLLFL Sorma GW-AQLRQQARSLELHTYAQFSNTETRLQELLDKRESVISHLTPS-AMKQNNLSLLRDKLLDHRRDLSRLRSTLESARTRANLLGSVRDD-ISAYRDYMLDERGRLDRSHDVADSVLSQAYAVQDSFASQRERLAHINRRITLAASQVPGINTLITRISARKRRDGIIMGSFIACFLMFW Sphar GAAVQSVKEIRVSGRVNY-----SVMSRSSMISELADLNDQMSSP-TVIH-TLQRHRDLLNDYTREFRKTKANLQSARDRTMLLSDVQTE-IRAYKDYYASEQARLNTAHSAVDDAIGIAIATREDLHTQRRTFQSTSQRLQGIAETIPGLNVLMKKIDVRKRRDQLIIAGVIACLFISI Spipu1 TW-ETLRRQARHLELVQYSKLGSAELELDHLLAKLTSVVNSMANP-SMMH-MLQRHRDILYDYSKEFKRTKANITAARDHADLLSSVRED-ISSYRDYLLTERGKIDGSHRMADEVLEQAYTTRAELHDQRSVLYNTRGRMGGVLARFPLVNDLISRIGAKKRRDSLIMAGVISCVCFLV Sporo1 -M-DTVRRDLHATTLTRYSKLAALELELGAALDTFSAHIDRLAST-SATH-ALERHRDVYREYLRDSERTKRSLQDAENRANLLGSVREE-ISAFKDSLLAERGKIDNSHRMADATLEQAYATRAEFAAQRSGLSQIQARMNGVAAQVPGLNSVIGMINSRRRRDSVIMGTIIGCTLALL Stehi1 TY-DSLHRQCRTLELTSYARLASVEQDVQELLEKLGEANDQLSSQ-SMLR-AIQRHRDVYQDYVRELRRTKANVKAALDQINLLSGVRND-IDAYKDSLLAERGRIDSSHQMIDETLDQAYATRSEFASQRTALGSIQTRMVGVLNTMPGINNLLSMIHKRRRRDSMIVGGLIGCLFFLL Tapde11 TW-GTLRAEQRLLEL------------LDSILAQRRTVLEDLAGN-KLQH--LNRHREIQQEHEEAASRVLQKSKEQKDRENLLGDVNED-IKKWKAYMLDERARIESSHTMADSVLAQAYATRDEFNLQKLSLQNIGQRISASSQKIPGMNTLLNKINTRQKRNSVILGTNPWR----- Thetr GYADV---------MGSVPGLGPLAAELDTLLLALKETVANMGPPPARVH-TLHRDREMLRDFEVEFRKTRDHVNNYLARIQLLDSMDEG-IAAYKEHVLREARAINATDRMTDALLGSAAASRAELLRETGQFRSINSRLADMSARFPLIGNIMSKIKSRKRRDMYILASVIACIIVIA Treme1 AW-DNARRHARALELSTYSRLAA-----------LEQAIDDLMSA-SMQH-AAQRHRDNLDDYRRDFLRTRNNVEAAVARSNLLGSVRKD-INDYKDALLADRGRIDSSHRMIDDTLNQAYATREDFAQQRTFLARIDSRLGGVLSQIPGINSLISMIHSRRRRDSIIVACVVACVLLLL Trire2 GW-AQLRQQARSLE----NQFSTVEAKLEDVLNKRENVIAQLGTS-ALKQNNLALLREKLASHRRDFTRLKSTLQQARNRANLLSNVRSD-IDEYRDYMLDERNRIDRSNDVTDSVLSQAYAINESFIVQRETLASINRRITMAASKVPGINSIIGRITSRKRRDGIIMGTFIACFIVFF Umbra1 SW-DSLRKQARQLELASLTKAGSLEFETEELLKRLQNVITSMSNP-SMLH-MLQRHKDIAFDYSKELRKVKASIRAAKDKADLLTQVRDE-IRTFHDYMLTERNKIESSHRMTDMVLDQAYATRDDLGRQRNMLRGVNSRMGGVLGRLPGINTLISRINTRRKRDTVIMALVISCTILIM Ustma22 PW-DVLRRNTRNLELTTYSQLASLETELESLINELSNSVDALTTT-PQLH-AVQRHRELLFDFTRDFRRSQTNVRHAIDRRDLLGNVQGD-IDAYKDALLAERARIDNSHGMIDRTLEQAYATRADFADQRSTLQAISTRMSSSAAQVPGLNSIITLIGRRKTRDSVIMGCLIGLTVLLL Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Zygro1 SF-VTVRSQAISLELSKYSTFAQLDTQLEELLNQRQDVVERLGAS-KLSQ--LQRHREMLKEHWQNLRNIRSSIQQERNRLNLLFSVKSD-IAQQRDYYRGESRRVDQSHNLVDRLISQAWETRDQFSAQSNLLQSGSNRVLQTLHRVPGINQLIARIGTRRRKNVLVMASVIVCILLLF [Cluster2224.fasta_al_trimmed; alignment length = 160] Allma1 IVLSGTTRAEQLVHIVNDEALQ-TAA-TEKKARAALLSAVERLLSPDLVIVDAMNYIKGLRYQLYCVARHCVIQCGVQEPVAREWNFDELVSRYEEPDGKNRWDAPLFFVPPNQSTELDKATNELVLAFFQMTVALATLKGIRRQFLKLNQFIHFLSESV Ashgo11 VLLTGTTYARQLVVYHSDETLK-TSQ-GEKSARSKIMSVVKRDLSRNIVIVDSLNYIKGFRYQLHCEVKYCLVHCLAAYEKLVQWNLEALIQRYEEPNPATRWDSPLFAVTPNSATVLDSETQAVVKTIMQDRVGMAQLQRIRRQFVQMNKFTEFLNKNL Aspfu1 HIHCCSYRAQQLIHIVPTHDPD-NAR-TEKEARGVAYTRAKRALGRDFVILDGMNYIKGYRYQLWCEAKSCVVHVGTPVDQCVANNLKNLIFRYEEPSTYSRWDKPLFTVKPHQATAMEKCTSAIVSAIRSGILALPRLQRLRRQWIGLNRFVRFLNAEF Aurde31 VTVSGSARVSQLIEVISDTSLN-DSR-AEKPARGAIFAAVQRHLSKNILIVDSLNYIKGFRYQMFCAAKVCTIFVVAPPDKCKEWHFDNLLMRYEEPSSMVRWDSPLFTIVANSGTTLEKTTTSLVASIIARNVTLSELQRHKRQFVTAHRFVVHLQQNL Batde5 VIICGTFRAKQIVIIINDESLS-NAT-IEKITRGTLLSATGRHLSKNVVICDGMNNIKGFRYQLYCVARTCTIHCGISLDTAKQSNFDNLCSRFEDPDGRNRWDAPLFTVAPNLSTEMDKTLSDIIEAFVDRTITPAELRRLKRQYTNINKFADYLNTNL Botbo1 ITISGSHRAEQLIHVLSDEEID-ESR-LEKPARSAMLTAITRHFSKDILIIDGMNYIKGYRYQIYCAARVCTLFVVATADMCRERNLDNLIMRFEEPSSMVRWDSPLFTIPPNQAVTLEQTSGTLVQLILSRNITLSELQRVKRQFVAVHKFISYLEETL Botci1 IILTGTYRATQLVHLISDHTLR-SNNASEKDARATIYGAVKRVLSNKVVILDGGNYIKGWRYQLFCEAKCCVLHVGVPADKAKEVNWDNLVFRYEEPNAMVRWDSPLFTVRPNAATELDKTTQTVLNRVLE----------------------------- Caeel IIVTGSTVVDRLYLIIRDEDYEFSNK--EKDLRSWIRSQVQQNLTKNVIICDALNYIKGYRYELFLAAKYCVVECSPPVATCHWLNIDQLMMRYERPDTKLRWEKPLFEVTENQSTELDRSTQDVVTVLLNKLRTLPELNRLRHQFVNMSKFVDFLNCNL Canalb1 IIFTGTKWAKLLVTYHSDETLQ-DSN-KEKLARGSQISAVKRDISRTIVILDALSYIKGFRYQLFCEAKHCIVHVIAPIEKCIQWNIKQLQMRYEEPNSDTRWDSPLFTIPPNAATELDKKTQEVVTKILQGTASTAQLQRIRRSYIGLNRFVEYLNRSL Cangl VLMCGSTVARELVVVHSDETLN-DTH-AERKLRNEIMSAVRRDLSRSIVIVDSLNYIKGFRYQLHCECKFMLVHCMATYADILKRDLDQLIQRFEEPDASNRWDSPMATVSQNNPTLLDAKLTETVRIIVRPQLTLPRLNRLKRQFVQMNKFVAYIGQTL Capow VLLCGTTRALELVHLINDESLA-NPT-NEKMARGALKAALERLCSREVVIVDSLNYIKGFRYELFCISRQCTIYCAAPAAEALAANFHELVQRFETPEERNRWESPLVTVLPNLGTELDTKTQEVVTFLLGATLTQAALRKHKRQFVTLAQFVRHLNASM Catan2 IILSGTTRAQQLVHIVNDESLN-APV-SEKKARGAMLSAVERLLSRDLVIADGMNYIKGFRYQLYCIARHCVIHCGAPLDLSRQWNFEELVTRYEEPDGKNRWDSPLFFIPPNMSTELDKATNELVTAYFQHKLSLPQLRGLRRQFLSLNNFIAYLQENV Cioin VVMCGTTRCGELVVVASD--LA-DSR-KEIETRGALKSAVERDVSDKVVIVDSMNYIKGFRYELHCVSKYCVIHCAASIQQIYQFNLDGLMQRFEAPNSMSRWDSPLFTIKPNLSTEADKMLQSIGASILADKLSVADMRRQRKQFLIYLRFLYFLSNSV CocheC53 ILISGTTRARQLVHLINDQTLR-TAR-AEKDARAEEYSAVKRVLSRDIVIADGLNYIKGFRYQLYCEAKSCVLHVGTPPDRCRENNFENLIFRYEEPNGMTRWDSPLFIVRPNMATELDKTTSDILTQIMVTPMTLPQLQRIRRQFITLNRFVDYLNAEF Coere1 IMMTGSTRARELVQVVGDDTLA-TAS-DEKKARGQLISAIERLVSREILIADAPNYIKGLRYQLYCVARQCVVHCAIPIPEARRINFEELVMRYEEPNPAVRWDSPLFTVLPTFSTELDRVTQEIINAILERNLTLSELRRMRMQFTKLNRFVNYLNINL Conco1 ITISGSKICNELVKIIDDDSF--DSPTSEKRLRGHLLAGVERTLNKQLVICDSCNYIKGFRYQLYCVARHSVVQVMAKPSDVLTWNIENLITRYEEPIGSNRWDSPLFPVPPNQSTELNTSCQNVMDDIISRNFSEPQLNRLKIKFISTVKFVSFLQNN- Conpu1 VTISGSRRADQIVVILSDDTLS-DSR-SEKPARGTLFTAMQRQMGQDILIVDSLNYIKGFRYQMYCAARVCTVWVVAKKEMCEEWNLENLFLRYEEPSSMVRWDSPLVTIPPNTGTTLEHTTAAVISSIISRNVTLSEMQRLKRQFVTVHKFATYLTENI Copci ITVSGSTRSSQLVQIISDDSLN-DSR-SEKPARGAIFTAMQREMSPNILIIDSLNYIKGFRYQMYCAARVATLYVVAPPDTCREWNFDNLIQRYEEPSSMVRWDSPLFTVPPNSGTILEQTTTSMVSSVLARNVTLSELQRLKRQFVTVHKFALYLDEHL Croqu1 IILSGTTRAEEIVVIVNDEQLN-DSK-SEKVSRGELLSNTIRLLSQNIILCDGMNYIKGFRYQLYCAARNCTVHIAAIPSDCISRNIENLISRFEEPNGSARWDSPLVVFPATAAVLLESTTSTIISEVLSKTINMSALQRLRRQYTTLQKFVQYLQGTL CryneH991 VTITGSTRAQQLVVVVDDESSD-SSA-QEKPGRASLFSNVNRSLGTDITIVDSANYIKGFRYQMYCAARVATIHVVAPPDMCRKWHFDNLIMRYEEPSSMVRWDSPLFTIPPTSAVTLTATTSLINSSLLSKKITLSEMSRLKRQYETVQVYVRFLEQTW Crypa2 IIVTGSTRANQLLHLISDQTQR-SANASEKDARAALSSAVKRVLSTKIVILDGSNYIKGWRYQLYCEAKNVLLQVGCSVDRARAINWENLVFRYEEPNPMTRWDSPLFTLKPNQAAVLDRETQDIVKSISERRVGLPQLQRYRRAFMNMNRFVGYLNDAF Debha1 ITFTGTKWAKKLIIYHSDETLK-DSN-MEKHARGSQMSAVKRDLSRTFVILDSLAYIKGFRYQLYCEAKHCVIHVMSSLNTSIQWNIKQLSMRYEEPNNDTRWDSPLFTIPPNAATELDKQTLAVIGKIVQTSVSIAQLQRIRRSYISLNRFVEYVNRSL Dekbr2 ILMVGSRWAQKLIKLYNDKNLR-ESV-SEKAIRGEQMSAVRRDLSKNIVILDASNYIKGFRYQLYCEAKYCVIQVIAPTDKCFQWNIKALIMRFEEPNGLNRWDSPLIPVKPNHATELDRMTSLVIDQIIQRVVTIAELQRMRRTYIASNRFADFMDHAF Dicdi IVLSGTTRAKELVIIINEESLK-DSL-TEKMTRGSLKGATDRNLSKDVVISDSLNYIKGYRYELYCIARLLVLYCNTPRDLAKKWNLDELTNRFEVPNPKNRWDSPLFTLRPNYATELETKTQEITSVISDSKLNLVELRNQRRQFYKFAQFVDFLNSSS Dmel VVITGSTRARQLVHLISENEATGDSQ-KEKVVRSDLKSEASRHLNQELVILDAGNYIKGYRYELYCMSKQCTVFTCIPQEEAWTFNFDALCQRYEEPQSNNRWDSPLVVVPPNQSTELDKIVQAIIKEILGTSMNALQLNRLRQKFITSTCFVQFINANT Enthi VLISGTTFANQLVELINEESLK-TMQ-TEDRMRTALKGQVLRFLNREIVILDSLNYNKSFRYELKCHCKSVTISVTAPKEKCIEWNVVELIERYEVPLPSHKWDQPLFNIRINFSVQIDAVTQDIIGVVMKRKVSVAEINRVRRSFLKLIQFVAFLNSAF Falba ALFDA--------------SI--GAR-TEPSAK--------------VVILDAPNYIKGFRYQLYCAARHCLIECQEPREGATVWNFDELHMRFEPPNGAQRWDSPLFVVRPHASTIRDRATQHVVAVFHRREFALQELHALRRRFLQLRAFASFLVEWL Fomme1 VTISGSCRAQQLVTVISDDNLD-DGR-QEKPARASLFTAMQRAIGKDIVIVDGMNYIKGYRYQMYCAARVCTVFVVAKPEQCREWNLDNLIMRYEEPSSMVRWDSPLFTVPPNAGTTLEATVAAMVSAITSRNITLSELQRLKRQFVTIHKFVTYLEENL Fusgr1 IIVSGSTRAKQLLHLISDESLR-SANASEKDARASIYGAVKRVLSDKIVILDGLNYIKGWRYQLHCESKSCILQIGCSVDKAREVNWDNLVFRYEEPNPMTRWDSPLFTLRPNQATILDRETSDVVKRIVEKKVGLPQLQRLRRAFMGLNRFVTYLNDAF Galma1 ITISGSTRAHHIVAVLSDHSLN-DSK-SEKPARGALFTAVQRQLSPDILIVDSLNYIKGFRYQMYCAARTCTVYVIASPDQSREWNVVSLFI-----------------------------TAPLISPIVS----------------------------- Ganpr1 LMMCGTTRALQIVDIVNDESLK-SPN-AEKPTRATQFSTLERQLTSDILISDSMNYVKGFRYQMHTLAKTAVVWCATDQPTCTQWDLTSLAIRFEEPDGRARWDSPLITIKPNLAVLLDRATTSVISSIPARHVSMSELRRWKNTWIGLVGFVKYLNDNL Gloin1 IVMCGTSRSTQIVHLINDESLK-DTRLEEKKSRGTLISAVERMISKDLLIVDAMNYIKGFRYQLYCIARHCVVYCGIPVEIAKEWNFDELVSRFEEPDDRNRWDSPLFTVPPNLSTELEKTTQDIINEVLDRTITLSEFRRLRRQFTNINKFVEYLNTNI Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 VLLTGTTVAKKLVVYHSDETLI-GSN-EERRARSKIMSVVKRDLSRQVVIVDSLNYIKGFRYQLHCEVKYCLIHTVCPMSNLVEWNLNALIQRYEEPNPQTRWDSPLFTIKPNNATILDSEASSVIKIIMKQNCSMPQLQRIKRQFVAMNRFVEYLNKHL Lacbi2 ITISGTTRANQIVVLLSDESLN-DSK-SEKAARGALFTAIQRLIARDLLIVDSLNYIKGFRYQVYCAARVCTVYVVATPDLCREWNIDNLIMRYEEPSSMVRWDSPMLTVPPNSGTVLEQITASMVSAILARHITLSELQRCKRQFITVHKFATYLEEHL Lenti61 ITISGTRRAQQLVAVVSDDTLN-DGR-AEKPARAALFTAVQRQMAQDILIVDSLNYIKGFRYQMYCAARVCTVFVVATHDQCREWNLDNLLVRYEEPSSMVRWDSPLFTVPPNAGTTLEHTSTTMVAAIMARNVTLSELQRLKRQFVTVHKFALYIEGNL Malgl1 LVVTGTTRVQEIVRVVQDADV--ESQRTEGRARAAYLSAVRRALSTSIVIADGLN-IKGSRYELWCAARCATLYVACTQDLCRAWNLDELMFRFEEPTPEARWHRPLFTTPPKAVT---------------RTVGAH----------------------- Mellp23 VVISGTTRAIEIVVIVNDELLD-DSK-SEKVARGHLLSHTIRHLSKGIVLCDGMNYIKGFRYQLYCAARNCTVHVAAVPSDCISRNIGNLISRFEEPNGSTRWDSPLVVF------ATKTESAVMV---------------------------------- Mnele ---------------------K----------------------------------LSGFRYELFCISKHCVVHTDVSRDTCQKWNIDELVMRFEKPNPSQRWDNPCFVVRPNQSTQLDISTQEILDIISSRNVNIAQLRRLKRQFITYTKFVQYLQSVV Monbr VLMSGTRRAEELVVMVSDDTAQ-SSA-SEKMARGNLKSEMSRLLNANVIIVDSLNYIKGYRYELYCAARSCVIQPLVRDELCLERHVRALMMRYEQPDDRNRWDKPLFAIPNY-STQLDAITRAIVQAVVQESLSMLQLKRIQRQFITYAKFVDFINRGQ Morel2 VILSGTTRAQELIHIVNDESLN-TAA-DEKKARGALMSAVERLLSKDIVIVDSLNYIKGFRYQLYCVARHCVIFCACIPDRARAWNFEELVVRFEEPDSRTRWDSPLFVMPPNMSTEFDQTTQNVIQAILDRVVTLSELRRLRRQFTSINKFVEYLNQNL Mucci2 IIISGTQRVNEIIQVINDESLN-DAR-EEKKARGALLSAVERTLSKDIVIADALNYIKGFRYQLYCIARHCVVQTGVPVDIAKEWNFDELVSRYEEPEERNRWDSPLFTLPPNKSTELDKATLEIINAFVERTVTLSELRRHRKQFVTYNKFVNYLNSNL Mydma VLICGTKIAHEIKVIVVSENDS-DFT-KEKEIRSALKAKVEQLLTRDVIILDGLNYIKE----------------------------------------------------------------------------------------------------- Neucr2 ILITGSTRAAQLLHLISDQSLR-SANASEKDARAALYGAVKRVLSPRIVILDTLNYIKGWRYQLYCEAKFGLVQIGCPVARARGVNWENLVFRYEEPNPMSRWDSPLFIIRANKSTVLEKETQDIVKRILEKKVGLPQLQRYRRAFVALNRFVGYLNDAF Orpsp11 IIICGTKRANEL---------K-DNNENEKGSKK---------------------------------------------------N--------EEP----------------------------------DSFGLDRIKTYS----------------- Pench1 VVLTGTHRANQLVHVVASHDSD-HAR-TEKEARGVAYARAKRVLKRDIVILDGMNYIKGWRYQLWCEAKCCVTS------------LNNLIFRYEEPSTHSRWDKPLFTVVPHQATAMEKRTSAVVTAIRNGVLALPRLQRLRRQWISLNRFVRFLNAEF Phybl2 IILTGTQRAAEIIHWINDESLK-DAR-EEKKARGAMMSAVERLLSKDIVIADGLNYIKGFRYQLYCVARHCVVHTGAPVQLAREWNFDELVTRYEEPEARNRWDSPLFTVPPNLSTELDKATLEIINAVIERTVTLSELRRLRKQFVSLNRFADYLNTNL Picst3 ITFTGTTWAKELIIYHSDETLR-DSN-LEKHARGNQMSAVKRDLSRSFVILDSLAYIKGFRYQLFCEAKHCVIQVINPIEKCIEWNVHQLLMRYEEPNGDSRWDSPLFTIPPNAATELDRQTQEVISKILQTPVSIAQMQRIRRTYISLNRFVEYVNRSL Plicr1 ITISGTRRAHQIVIIVSDDSLD-ESR-SEKPARGALFTAMQREMGQDILIVDALNYIKGFRYQMYCAARVCTVFVVATHDLCREWNLENLLVRYEEPSSMVRWDSPLFTVPPNAGTTLEQTTTSMVAAILSRNLTLSELQRAKRQFVTVHKFVSYLEENL Polpo ILLSNTARANDIVIIINEESQK-DSL-SEKMTRGTLKAAVERSLTKDIVIADSLNYIKGYRYELYCIARLLLVYCQTPREQSKQWNLEELTNRFEVPNPKNRWDSPLFTLRPNYATQLETVTQEIANVVLDSMLNAAELRNQRRQFYKFAQFVDFLNSKT Pucgr2 --MTSTMVSCSVIT---------ESK-TEKVARASLLSSTIRKLSKDIVICDGMNYIKGFRYQLYCAARTCTIHVANLQANCLAYNIQNLFTRYEEPNSSVRWDSPLIVFPVHAAVVLEITTTSVLTSLLSKTVNVGVLQRLKRQYTTMHKFVKYVQGAI Punst1 ITVSGTRRAEQLVVVVSDDTLN-DSR-SEKPARGALFTAAQRAMGRDILILDSLNYIKGFRYQIYCAARMCTLYVVATHEHCRTWNLDNLLLRYEEPSSMVRWDSPLFTVAPNVGTTLEHITASIVSCIMARNASLAELQRLKRQFVAVHKFAEYLEENV Rhior3 IVLTGTQRTNEIIHIINDESLK---------------------------------------------ARHCVVYTGIPVEKAKEWNFDELVSRYEEPEERNRWDSPLFTIPPNKSTELDKATLEIINAFVERTVTLSELRRFRKQFVTYNKPVMYYKT-- Rhoto1 ITVCGTTRALQLVVLINDESLD-DTR-AEKPARAALFSAVQRSLAKDIVVVDAMNYIKGSRYQMYCAARTCTLFVATPPDKCQEWNLDNLISRFEEPNSAARWDAPLVTLPPNIATLLDSASSSVISSLLSRQLTLPMLQRLKRQFVQLHAFGTYLGEQL Rozal11 VIITGTKRAEQLVVLLNEEFLN-NSN-DEKKVRGALVGAVERYLNKKLVICDSMNYIKGIRYQMYCIARQCVVHICTSSENCSKFNLKNLISRYEEPNEFNRWDKPLFNVLPNLSTNIDQTIQKATKTVLENRVTLIEMKRHQHQFMKLYNFVEYLNSQF Sacce1 VLFTGTTLAKHLITYHSDESLI-TSQ-DERKLRSEIISAVKRDLSKNIVIVDSLNYIKGFRYQLHCEVKFCVIQTLCPPETIFEWNLNQLIQRYEEPNSSNRWDSPLFAIKPNSATVLDIETSKIIKTIMNNVVTLAQLQRLKRQFINFNKFADYLNKNL Salro VVLCGTRRAKEVSVIVGDESEE-TPK-VEKTTRGVIKSAVDRALAKDVVIVDSLNYIKGYRYELYCLARHCIVHTLARDAECIARHAK-LIQRFEAPNDHQRWDRPTFAVKAHQATELDRITQAIVAAILKRKFTMSELRRSRQAFITYTKFVNFLNHSS Schco3 ITISGSTVAQKVVVIVSDESLN-DSR-SEKPARGALLTAVQRNMNQDILIVDAPNYIKGFRYQMYCAARVCTLYTVATADVCRSRNLENMIARFEEPSSMVRWDSPLFTIPPNAGTALEQTTTALVSAISTRTVTLPELQRLKRQFVTVHKFAAYVEENV Schpo1 IIVSGTTRSNELVIIINDESLR-ESK-NEKAARGLLYSAVQRELSKSFVICDALNYIKGFRYQLYCESKHCVIHVAVPQDLCRKFNLEQLMFRYEEPNGMTRWDSPLFTVKPNQATELDKTTQDVIMLILDVTVSLPLLQRLRRQFIQINRFVEFLNGQF Sorma ILITGSTRAAQLLHLISDQSLR-SANASEKDARAALYGAVKRVLSPRIVILDTLNYIKGWRYQLYCEAKFGLVQIGCPVARARGVNWENLVFRYEEPNPMTRWDSPLFILRANKSTVLEKETQDIVKKILEKKVGLPQLQRFRRAFVALNRFVGYLNDAF Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 VNLCGTTRAHQLVIIVNDESLA-SPH-EEKKARGALISAIERHLSRELVICDAMNYIKGFRYQLYCIARHCSIHCGVSPSTAEIWNLQDLCTRFEEPDARNRWDAPLFTLPPNLSTEMDRTTQEIVDTILARVITLSELRRLRRQYTNLNKFVEYLNTNI Sporo1 VTFSGTTRARELVLVINDESLDGQSR-SEKPARASLFSAVQRHLGPDIVIVDAMNYIKGSRYQMYCQARNCTVFIATPPDRCRAWNLDNLMSRFEEPSSSARWDSPLITIPPNLATVLESTTSSVVAAVLS---SMPQLQRLKRQFVTMNKFAKYL---- Stehi1 ITISGTRRAEMIVVSISDDTLD-DSR-SEKPARGALFTAMQRQMGQDLLIVDGMNYIKGFRYQMYCAARVCTVHVVAPPESCKRWNLENLIQRYEEPSSMVRWDSPLITVPPNAGTTLEQTTTALLSLIISRTVTLSELQRLKRQFVTVHKFGVYLEENL Tapde11 LIMTGSHWARKICVVINDESLS-EAR-REKAARGLLFSAVERYLGKEIVLCDGLNYIKGFRYQLSCSAKHCLVHVGCPVDQCTKFNFEELIMRYEEPNTSSRWDSPCFNIRPNASTELDRVTQSVIASIMDQAVGVAALQRLKRQFINLNKFVEFLNDQW Thetr ITMCGSRRAAEMVVTVSAESLA-EPS-AEKTLRAEFKAAVEREIGPGVVICDSLNYIKGFRYELYCDAKSCVVWCDTADELAEGWNFDDLWMRFEEPNGRKRWDKPLFVVKPNESTALDGLTRSVVDAVLARKVTPAEIRRARKQYLKL--FADFLASTI Treme1 VTLVGSTLASKLVVIISDESCD-DSK-SEKSGRATLFASLTRALGPNIVICDSLNYIKGFRYQMYCSARVCTVHIATPAEQCVKWHFENLIMRFEEPSSMVRWDSPLYLIPPTAAVVLSGTTSHIISTLLTRRVLLPDNG-----------FVKFLEIQW Trire2 IILTGSTRAKQLLHLISDDSLR-SANASEKDARAAIYGAVKRVLSDKIVILDGLNYIKGWRYQLHCEAKSCILQIGCTKERAQQ--WENLVFRHEEPNPMTRWDSPLFTIKPNQATVLDRETQDIVKRILDRKTGLPELQRHRRAFMALNRFVNYLNNAF Umbra1 IIITGTRRSEEIIHIVNDEVLK-EAR-EEKKARGALMSAVERLVSKDLVIADGMNYIKGFRYQLYCVARHCVVHCGTPINMAREWNFEELITRYEEPDGRNRWDSPLFTVPPNLSTELDKMTLDVINCVLERAITMSELRRHRRQFTTMNKFVDYLNTNL Ustma22 IIVSGSTCSALIVVIVSDHDVA-SQR-TEKPARASYLSAVTRALGKDLVIADGLN-IKGFRYQLWCAARCLSIHVHAPPQVCRYWNLDSLLMRFEEPNAMTRWDSPLIIVKAPEVVILESSTQTVVSCILQKPVTMASLQRIRRQFVRMHSFLAFLEGAL Walse1 VVVTGTRRSKELIRLVSEHDFR-DTR-LEKPARGAVYAAVERYLDKNIVICDAPNYIKGFRYQLYCTARNMTLWTIATPDQARELNFEELAFRYEEPNGASRWDQPLVSAKVNIGVVLEATTTQVSGAITTKQITPAQMNRYRRAFVGLHRYLLFIQTTL Zygro1 VLFTGSTKARELVILHSDESLS-TSQ-GERKLRSEIFSAVRRDLSKSVVVVDSLNYIKGFRYQLHCEVKYCLINTMCPIDSIHDWNLEQLIQRYEEPNANNRWDSPLFPIAPNNATILDSQTGNVVKKIMDQSVTLPHLQRLKRQFVNFNKFAEYLNKNL [Cluster2226.fasta_al_trimmed; alignment length = 206] Allma1 MAHSKYEYVKAFEDKLLP-NTWIVVRVDGKGFHKFTKEHQFTKPNDITALQLMNHAAAAVMDLTLAYGQSDEYSFLFKRNTDYYSRREVKLASVIGSLFTAHYVLAWPAFDA-RAVPYPSIENVRDYFAWRQADHINNLYNTSFWALVKG-GLTENVAMKRLSKTVAKDKNELLFSEFGINYNDEPEMFKKGSTLHCSII-DEAFW Ashgo11 MAKSRFEYVREYEDTLLP-ETYIVVRIDGKHFHEFSQHYSFEKPNDERALKLMNASAKNVVDIILAFGESDEYSFILRKDSTLFRRRRDKLSTLFVSLFTAQYVALWPFFDS-RCVCYPNTTVVKDYLCWRYVDHINNLYNTVFWNLVKC-NLTPREAEQRLSGTLSSDKQEILFSECGVNYNNESEMFKKGSLIHIDVV------ Aspfu1 MANSKYEYVKSFEDVLLP-NTWIVVRIDGRGFHKLSDRYGFIKPNDRRALDLMNAAAVEVMDLCIAYGVSDEYSLRFSP--QLSVVRATQRV---------------PSFDG-RAVLYPTTRILRDYMSWRQVDHINNLYNTTFWTMVKG-GMSNTDAERELHGTVSSDKNEILFKRFGINYNNEDEMFKKGSVVHVDII-KDEFW Aurde31 MAGTRFSYVKTFEDPLLP-ETYMVLRLDGHGFHKFSDTHGFAKPNDERALQLMDAAAAAVMDVVLAFGESDEFSFLLRKKCTLYNRRQSKILSTLVSFFTSVYVLRWPSFDG-RIVLYPAQQHVRDYFAWRQADHINNLYNTTFWALVQG-GQSTTQAHETLKGTVASGKNEMLFSRFGINYATLPARFRKGSVLHEDII-ENQFW Batde5 MAASRFEYVRLFETSLLR-NTWIVVRVDGHGFHRFSKTHTFAKPNDTRSIRLLNHCAAVVMDIVIAYGQSDEFSFVFHPSTTLYGRREAKIITNLCSIFTSSFVMNWPSFDA-RAVCYPTVLNLKDYLSWRQADHINNLYNTAFWALVKE-PKSETEAEAILRVTDAAAKNELLFSRFGINYNTIDPLFRKGSVLHVDII-GEQFW Botbo1 MAVSRFAYVKSYEDPILP-NVYVVFRLDGHGFHRFSDIHWFAKPNDERALELMDRAARDVMDIVLGFGESDEFSFLLRRSCTLYSRRQSKILSTLTSHFTSCYVFHWPSFDG-RLVVYPTQTEVRDYFSWRQSDHVNNLYNTVFWALVQG-GMSTTEAHEKLRGTVSSAKNEILFTEFGINYNKLPTRFRKGSTLHCDII-GKEFW Botci1 MANSK-----------------------------FSDKYAFEKPNDRRALDLMNAAAKAVMDIMIAYGISDEYS-----------------------------------FDG-RAVQYPSVQNLRDYMSWRQVDHINNLYNTTFWTLIKG-GFDAKGAEKELAGSLAADKNEILFSRFGINYNNEPEIYKKGSVV----------- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MANSKYEYVKLFENYLLP-DTYIIIRVDGKGFHKFSQFYEFEKPNDLKALQVMNSAAEKLMDVMLAYGDSDEYSFLLRKNCQLYERREMKLTTLFSSLMSTYYMYFWPNFDA-RAVLYPDFKHIRNYFSWRQVDHINNLYNTTFWNLVKL-KMTPQQAEQRLMGTVASDKNEILFKECGVNYNNESEMYKKGTIIHVDIINDDSWW Cangl MAKSKYEYVKQFEDTLLP-QCYIVVRIDGKKFHEFSKYYDFKKPNDERALKLMNACAKNVVEMILAYGESDEYSFVLKKDTELYKRRRDKLSTLIVSLFTSNYVALWPFFDS-RCVIYPNLETIRDYVTWRYVDHINNLYNTAFWQLIKC-GMNPQEAEKRLSGTVSSEKNEILFKECGINYNNEPEMYKKGSLIHINVI------ Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 MAKSKYEYVKLYEHTLLP-NTWVVVRVDGKGFHKFSKQYNFDKPNDEAALQLMNYAASKVMDLTLAYGQSDEYSFLFRRSTDLYCRREIKLASVIGSMFTAHYIHGWPVFDS-RAVPYPTRENVRDYFSWRQADHINNLNNTVFWALVRGSGMTEHAATMRLQKTNAKEKNEILFSEFGINYNNEPERFRKGTTLTEDII-GDAFW Cioin MTHSQYDYVKSFEDPCLP-NCWPVVRIDGKNFHKFSTTHNFEKPNDDRALKLMTAAATSVMDIVLAYGQSDEYSFVFKKKTKAYNRRSSKLSSVVVSQFSTSYVYHWPAFDS-RLVLYPSDKNLRDYLSWRQVDHINNMYNYCFWKLV---GLTHVESQERLKGTLSGDKNELLFSQFGINYNNLPQLHRKGTVIHLAKI-AR--- CocheC53 LAMPRYEYVRLFEDILLA-NTWIVVRIDGRGFSKFTTKYNFTKPNDKNGIDVMNAAAKAVMDLVMAFGNSDEYSFVFHKDCTLFERRASKLTTTIVSTFTSYYVYSWPSFDG-RAVCYPSNTNLRDYMSWRQVDHINNLYNTTFWALVQG-GMGHREAEERLKGTVSSDKNEILFKEFGINYNNEPNCFRKGTVLHVDII-KDDFW Coere1 MANSRYEYVRQFEDRLLP-STWLVVRIDGQGFTKFTAKHGFEKPNDIRALHLMNRAAMTVVDIVIAYGQSDEYSFVFSKDTQAFDRRASKLTTLLVSQFTSAYVFYWPAFDS-RVVMYPSERIMRDYLCWRQADHINNMYNTCFWTLVRG-GLTEKEAERRLRGTLSRDKNELLFSEYGINYNAIENIFKKGSVVHCDII-KDAFW Conco1 MAKSKYEYVKNFEDSILP-STYIVVRIDGKGFTKFTQTHEFIKPTDKRAIELMNLCALEVVEITVAYGQSDEYSFLFKKDCQLFERRSSKLATTVVSIFTANYVFHWPSFDG-RSVCYPNIEVLRDYFSWRQVDHINHLYNLCFWKLV---GVSRKSAEKQLSGTVSKDKHELLFSKFDTNYNDEPEMYKKGTVIHVDII-KKNFW Conpu1 MAGSKYAYVRNFEDPLLP-GTFLVCRLDGHSFHRFSDEHGFSKPNDERALRVMDAAAQSVMDILLSFGESDEFSFLLRKSTQLYNRRHAKILTTLTSYFTSCYVFHWPSFDG-RIVQYPSAREVRDYFAWRQVDHINNLYNTTFWALVQG-GQSTTQAHATLKGTFSKQKHEILFSRFGINYNALPEQFKKGSVLHCDII-GDAFW Copci ----------------------------------------------------MDRAARELMDIVLAFGESDEYSFLLKKSTTLFNRRQAKILSTLVSAFTGFYMFYWASFDG-RIVVYPSEKEVKDYFRWRQADHINNLYNTVFWALV---GKTTTEAHAVLKGTYSKDKHEILFTQFGINYNNIDARFRKGSILHCDLI-RDEFW Croqu1 MANSRFGYVRGSEDRLLP-QTYVVIRLDGKGFTKFSSAHAFEKPNDKRALRLMNEAAKRVLGILLAYGQSDEYSFAFSRRCDAYNRRASKLLTIVLSTFTAAYIHLWPTFDG-RIIQYTSDEELRDYFKWRQADHINNLYNTTFWALILG-HSTHAEAHAALKGSLSRDKHSILFDRFRINYNAEPEIFKKGSILHEDLI-KDQWW CryneH991 MAKSRFEYVKKFEDPLVP-NTYIIVRIDGKGFHKFSDVHSFDKPNDIRALQLMNTAAKSVLDVVMAFGESDEYSFLLRRTTTLYNRRRS--------------------FDG-RVVLYPNVKEVRDYFSWRQADHINNLYNTTFWALV---GLTTAEANKTLQGTNSKDKNEILFTKFGINYNTLPEMFRKGSVCHMDII-NDMFW Crypa2 MANSKWEYVKQFEDQLLP-NTWIVVRIDGRGFTKFANKYAFEKPNDKRALDLMNEAAKLVMELIIAYGISDEYSFVFHKTCKLFERRESKLVTTIVSTFTSYYIFLWPSFDG-RVVCYPSVSNLRDYMSWRQADHINNLYNTTFWALIQG-GMNNQQAEQALLGTVSSEKNELLFSKFGINYNNEPEIYKKGSVIYLDII-KDEFW Debha1 MAKSRFEYVKQFENFLLP-DTYLIVRVDGKGFHKFSEEYEFSKPNDIRALKVMNNAAKNLMDIMMAYGDSDEYSFLLRRKCSLFERREMKLVSTFASFISVNYLYEWPTFDA-RIVVYPTIKHIRDYFSWRQVDHINNLYNTTFWTLVKG-GMTGREAENKLLGTVSSDKNEMLFKEFGINYNNESEIFKKGTILHLDII-GDTFW Dekbr2 MANSRFEYVRTFENILLP-QTHIIIRIDGRGFHKFSSAYEFQKPNDPNALKVMNLSAQALMDVMMAYGDSDEYSFLLRKNCDLFERREFKLITAFSSGFSAYYQYYWPTFDA-RAVVYPSDSIVKDYFRWRQVDHINNLYNTSFWNLVKG-HLSPQEAENKLMGTVSSDKNELLFKEFGINYNDEPEMYKKGTVFHCDII-KEEFW Dicdi MANSKYEYVKSFEDILLQ-NVWIVVRIDGRSFHKFTTKHDYAKPNDDRGLSLMNRAALEVCDIVIAFGESDEYSFVLKKSCNLFERRSSKISSSIVSYFTSQFVYRWPTFDS-RCVLYPTDENIKDYLSWRQADHINNLYNTCYWALVKA-GKTPIEAENELRGTFSDGKNEMLFSRFNINYNNLPAEYRKGSVIHVDII-SEKFW Dmel MACSRFEYVKSFEDSILP-NVWIVIRIDGKKFHKFSKTHDFEKPNDENALNVMNAAATAVMDIVLAYGQSDEYSFVFRKETAAFKRRSAKLLTYVTSLFSSSYVMQWPCFDG-RVVLYPSEQNLKDYLSWRQADHVNNLYNTAFWKLVEK-GLTNQQAEAKLRGTFSADKNELLFQEFGINYNNLPAMYRKGTILHEDLI-SSQFW Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MANTRFAYVRHFEEYFLPRDTWLVIRVDGRGFSRFTQAHNYVKPNDVRGIQLMNRAAMHVAECCAAYGQSDEYSFVLHKSTQLYSRRLSKIASSVSSAFSSAFVFHWPAFDS-RVVSYPTVQHVRDYFSWRQADHINNLYNTCFWALVQG-GMTPPEAEARLDGTFSNDKNELLYSQFGINYNTLSAVFRKGTFLHIDII-GDNFW Fomme1 MAGTKYAYVRAFEDPLLP-NTFIVCRVDGHAFHRFSDIHGFEKPNDVRGLRLMDTAAYAVMDIVLGFGESDEYSFLLRRSTQLYNRRESKILTTLVSHFTAAYIFNWPTFDG-RIVLYPTSREVRDYFSWRQADHINNLYNTVFWALVQG-GQTTTEAHATLRGTVSSQKHEILFSRFGINYNNIEPQFRKGSIIHEDLI-GDGFW Fusgr1 ----------------------------------MCAKYAFEKPNDRRALDLMNTAAKAVVDITIAYGVSDEYSFVFHKACTLFERRASKLVSTVVSTFTANYVYFWPSFDG-RAVCYPSVQNLRDYMSWRQVDHINNLYNTSFWSLIVK-GLDNKEAEKRLAGTYAADKNEILFSECSINYNNEPEIYKKGSVIHVDII-KDDFW Galma1 MANSKFAYVRDFEDPLLP-GTFMLFRLDGHSFHRFSEQHEFKKPNDGRALELMDHAAKDVMDITLAFGESDEFSFLLRKSASLYNRRQSKIVSTLTSLFTSSYVFHWPSFDG-RIVLYPTEKNIRDYFAWRQADHINNLYNTTFWALVQG-GQTTTEAHATLRGTFSKEKHEILFSRFGINYNQLNERFRKGSVLHCDII-KDDFW Ganpr1 MAKSKYEYVRAFEDAILP-STFILVRVDGRNFSTFTKKHNFSKPLDFRGVAIMERAAQTVMDIVLAFGQSDEFSFLLKKSSNLYNRRASKLVSSVVSLFTSAYVFWWPSFDG-RAVCYPTEKEVKDYFRWRQADHINCLYNTCYHHLT---PLTPSEAEVLLSRTDSSMKNELLFKGFGVNYNALPPAARKGSVLYVDLI-SEAFW Gloin1 MAKSKYEYVKQFEDSLIP-NTWLVIRIDGRGFHKFSERHQFEKPNDRRALDLMNKCAETVMDIILAYGQSDEYSFVLKKECDLYCRREAKILSTIVSLFTSNYVFLWPSFDG-RIVQYPSDNNLRDYLSWRQADHINNLYNTCFWALV-S-GKTETEAENILRVM----------------------------------------- Hisca1 ------------------------MFVEGRELTKL--------------------------------------------------------------------------LEG----------------------HINNLYNTTFWNMIQG-GMSNTEAEKALQGTVSGDKNEILFSRFGINYNNEPEMFKKGSVIHLDII-KDDFW Klula1 MAKSRFEYVRQFEDALLP-DTYIVVRVDGKKFHEFSKYYNFAKPNDERALKLMNAAAKNVFEMICAYGESDEYSFILKRDTKLFNRRRDKISTLFVSLFTANYVSLWPYFDS-RCVCYPNLTVVKDYLSWRFVDHINNLYNTVFWYLIKC-GLTPQESEQKLCGTLSSDKQEILFSECGINYNNEPEMYKKGSLVHIDVV------ Lacbi2 MANSKYAYVRDFEDPLLP-GVFMVLRIDGHSFHRFSEKHNFAKPNDVRALQLMDHAAQDLMDVVLGFGESDEFSFLLRKSTSLYNRRHSKIVSTLTSLFTSSYVFHWPSFDG-RIVLYPGTKEVKDYFAWRQADHINNLYNTTFWALVQG-GQTTTEAHSTLRGTFAKDKHEILFSRFGINYNQLDAQFRKGSVLHCDII-KDEFW Lenti61 MAGSKFAYVRNFEDPLLP-GTFMVLRIDGHAFHRLSEEHNFMKPNDERALQLMDHAARDVMDIVLAFGESDEYSFLFRRSASLYNRREAKILTTVTSLFTSSYVFNWPSFDG-RIVLYPSPSVVRDYFSWRQADHINNLYNTVFWALVQG-GQTTTEAHATLRGTVSSQKHEILFSRFGINYNELPARFRKGSVLHFDII-GDEFW Malgl1 ------------------------------------------------------------MHITLAFGESDEYSFLIDKNSTLYNRRQSKLVTHIVSLFTSAYVFYWPSFDG-RLVVYPGEQEVRDYFSWRQADHINNLYNTVFWALVEG-KKTEREAHNILKGTVSADKHEILFKEFGINYDKLPAFFRKGTTLHVDII-GDDFW Mellp23 MANSKFGYVRLSEDRLLP-QTFAVIRLDGKGFTKFSSAHAFEKPNDQRALSLMNEAAKRVVGIFLAYGQSDEYSFAFSRGCDAYNRRASKLLTTVLSTFTAAYIYLWPTFDG-RIIQYVTDQQLRDYFKWRQVDHINNLYNTTFWALVRG-KQTHTEAHASLKGTLSRDKHSILFDKFQINYNGEPEISKKGSILHEDLI-KDQWW Mnele MAKSKFEYVRLYEDKLLK-NVWMVVRVDGKGFHKFTTDHKFEKPNDLAALNLMNDAAKGVMDVFMAYGQSDEYSFIFKRSSTLYGRRSSKIISTVCSMFTSHYLFNWPSFDA-RVVLYPCLRDVKNYFSWRQADHINNLYNTCFWALVKG-KLSTLDAEKRLNGTVSSDKNEILFSEFGINYNNISEIYRKGSTITCDII-DNSFW Monbr MANSRFQYVRGFEARLLP-NTWIVVRIDGRGFHKFSAKHGFKKPNDARAINLMNAAAVACMDIVMAYGESDEYSFVFDKRTQLFSRRGDKIMSSIVSFFSSTYVMQWPHFDG-RCVLYPTLENLRDYVAWRQVDHINNLYNTTFWTLVKG-GLTEYEAEQRLVGTFSKDKNELLFSEFGINYNEEPLMFRKGSVLHCDLL-QEEFW Morel2 MAKSKYEYVKEFEDRMLR-NVYVLVRIDGKGFHKFSQTHDFAKPNDVRGINLMNHAARCVMDIVLAFGESDEYSFLFRKSTDLYQRREAKIVSTVVSLFTSAYVYYWPVFDG-RAVLYPSEVEVKDYFAWRQADHINNLFNTSFWALVEG-GLTPKAAEARLCGTDSKDKNEMLFTEFNTNYSKLPAMYRKGSVLHIDII-GEKFW Mucci2 MANSKFEYVRHFEDNMLP-STWLVVRIDGRGFHRFSQTHNFAKPNDRRAIELMNRCAIEVMDIILAYGQSDEYSFIIPKSSNLYSRRSSKISSTVVSLFASNYVMHWPCFDS-RTVCYPNDKVLRDYLSWRQADHINNLFNTTFWALV-S-GMTEDAAEKHLRGSFSKDKNEILFVEFNINYNNIEPIYRKGSTIYDDII-GQDFW Mydma MAKSKYEYVKKFEETCLL-NCWIVVRIDGRGFHKFTHDHLYEKPNDIRGLSLMNFCAKEVMDIVISYGQSDEYSFVFSKNTSQFKRRSCKLMSNIVSLFSSSFVFYWPQFDG-RIILYPSLENIRDYLSWRQADHINNLYNTCFWSLVKG-GLSTLDAELKLKGTLAKDKNELLFSEFDVNYNDISPIFRKGNIVHDDII-GENFW Neucr2 MANSKFEYVKQFEDSLLP-NTWIVVRLDGRGFTKFSTKYAFEKPNDKRALDLMNAAARSVMDITIAYGVSDEYSFVFHKSCTLFERRASKLVSTIVSTFTAYYIHHWPSFDG-RAVCYPSVQNLRDYMSWRQVDHINNLYNTTFWALIQG-GMDGTAAELMLKGTFSADKNEILFKKFGINYNNEPEMFKKGSVVHLDII-RDEFW Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MANSRFEYVKSFEDVLLP-NTWIVVRIDGRGFHKLSDHYAFAKPNDRRALDLMNAAAVEVMDLCVAYGVSDEYSFVFHPNCQLFERRNGKLVTTIVSTFTAHYIYKWPSFDG-RAVIYPNNRILRDYMSWRQVDHINNLYNTTFWTMVQG-GMSNTDAEQELKGTVSADKNEILFKRFGINYNNELEIYKKGTVLHVDII-KDEFW Phybl2 MANSKYEYVRHFEDKVLP-NTWLVVRIDGRGFHRFSQTHEFQKPNDRRALELMNQCAIEVMDIILAYGQSDEFSFVLPKSCNLYSRRASKIASTVASLFAANYVMHWPCFDS-RVVCYPSDQNLRDYLSWRQADHINNLYNTTFWAIV-S-GKTEIESEEILRGTFSKDKHEILFTNHNINYNKLEDIYKKGSTIYDDII-GQEFW Picst3 MAKSRFEYVKQFENYLLP-DTYIVIRVDGKGFHKFSQEYEFDKPNDIRALNVMNRAAQAVVDVLMAYGDSDEYSFLLRKNCQLYERREMKLITMFSLMILTNYFYFWPNFDA-RAVLYPNFALIKDYFSWRQVDHINNLYNTTFWALVKG-GMTPQEAENRLIGTVASDKNEILFLQFGINYNNEPEIFKKGTIIHEDLITSETFW Plicr1 MANSKFAYVRKFEDPLLL-GTFMVFRLDGHAFHRFSDEHGFAKPNDERALQLMDRAARDLMDIVFGFGESDEFSFLLKKSTALYHRRNAKIVSMLTSFFTSSYVFHWPSFDG-RVVLYPTEREVRDYFSWRQADHINNLYNTVFWALVQG-GETTTQAHATLRGTVSAQKHELLFSRFGINYNQISARYRKGSIIHCDII-RDEFW Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ----------------------------------------------------MNAAAIQVLGIVLAYGQSDEFSFAFGRNCQAYNRRSSKLLTTVLSTFTAAYIHLWPTFDG-RIIQYATFQEFQDYFKWRQVDHINNLYNTTFWALVQG-KRTTQEAHSDLKGTFSKDKHSILFDRFQINYNNELEIFKKGSILHQDLV-KDQWW Punst1 MAGSRFSYVKNYEDPLLP-GTFILARVDGRAFHRFSTEHEFTKPNDERALNLMNCAARGVMDIILAFGESDEFSFF--ASTSLYNRRMSKILTALTSIFTSMYMFHWPSFDG-RIILYPSEQEVRDYFAWRQVDHINNLYNTAFWALVQG-AHSTADAHAVLRGTLSGQKHELLFSRFGINYNALPARLRKGTLLHCDVV-GEEFW Rhior3 ----------------------------------------------------MNRCAIEVMDIILAYGQSDEYSFVLPKSTNLYSRRASKISSTIVSLFASNFVMHWPCFDS-RTICYPNDQVLKDYLSWRQADHINNLYNTTFWTLV-S-GMTETEAEARLRGTFSKDKNEILFSEFNINYNNIEPIYRKGSTIHEDII-GQQFW Rhoto1 MAGSRYTYVKGFEDPLLP-STFFVIRIDGKGFHGFSKAHNFDKPNDWNALTLMNEAAKRVVECVMAFGESDEYSFVFKRSCKLHGRRSSKLVTLVVSVFTAAYVALWPVFDG-RVVQYTNEAEVRDYLRWRQVDHINNMYNTVFWALVQG-GRTPVEAEQELSGTISSQKQEILFSQFGINYNNLEPMYRKGSLVHEDLI-SDAWW Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 MANSKFGYVRQFEDVILP-QCYIVVRIDGKKFHEFSKFYEFAKPNDENALKLMNACAKNLVDIILAFGESDEYSFILKSSTTLFNRRKDKLATLFGSFFTSNYVALWPYFDS-RCVAYPNLQTIKDYLSWRYVDHINNLYNTTFWQLIKC-GLTPQESEKKLCGTFSNEKQEILFSECGINYNNEPEMFKKGSLVHINVI------ Salro MAKSRFEYVKLFEETALP-NTWMVVRLDGRGFHRFSALHEFEKPNDARALELMNEAARECMDIVLAYGESDEMSFVLDRRSNLFKRRKSKVMSTIVSLFSSTYVMRWPHFDA-RVVCYPTLQNLKDYLSWRQADHINNLYNTAFWLLVKK-GLTEQEAESRLRGTFSADKNEIMFSECGVNYNNEPAMFRKGSVIAQDMI-GPAFW Schco3 MAGSKFAYVRNFEDPLLP-ETFMVFRLDGHSFHRFSDTHNFVKPNDKRALELMDYAALRLMDIVLGFGESDEYSFLLRRSTNMYNRRQSKIVTTLTSFFTSTYVMYWPSFDG-RIVLYPAEQHIRDYFAWRQADHINNLYNTVFWALVQG-GLTTTDAHAALRGTISKEKNEILFSRFGMNYNSIDERYRKGSVLHCDII-KDDFW Schpo1 MAKSRFEYVKQYEDRLLP-ETYIVIRIDGKGFHKFTKKHDFEKPNDLRCLNLMNAAARVVMDIVLAYGDSDEYSFVWSKSTELYERRESKLVSHVCSLFTSAFVFNWPSFDG-RAVLYPNMKVLRDYLHWRQVDHINNLYNTTFWMLIKG-GFTNTQAEEYLKGTVSAEKHEILFSKFGINYNFEPEIYKKGSIWHVSLI-DDDFW Sorma MANSKFE---------------------------FSTKYAFEKPNDMRALDLMNAAARSVMDITIAYGVSDEYSFVFHKSCTLFERRASKLVSTIVSTFTAYYIYFWPSFDG-RAVTYPSVQNLRDYMSWRQVDHINNLYNTTFWALIKG-GMDGTTAELMLKGTFSADKNEILFQKFGINYNNEPEMFKKGSVIHLDII-RDEFW Sphar -----------------------------------------------------------------------------------------KIVSTCTSLFSSAFVYYWPVFDG-RMVCYPTLLNMRDYLNWRQADHINNLYNTVFWALVKG-GMSQKDAEVHLKNTATYD------------------------------------- Spipu1 MACSKYEYVKLFEITLLP-NTWLVVRVDGHSFHRFTSEHDFAKPNDIRSLQLMNYAAQRCMDIVLAYGQSDEFSFVFRRSTNLYKRREAKITSTLCSLFTSNFIFHWPSFDA-RAVCYPTDQNLRDYMSWRQADHINNLYNTAFWSLVSN-PRTEREAQAILKDTDSAAKNELLFTQYGINYNKLPEIFRKGSTLHGDII-GDKFW Sporo1 MAGSRYEYVKRFEDPLLP-STFFIIRLDGKGFHGFSKAHDFAKPNDTNALTLMNEAAKRVMECVMAFGESDEYSFVFKASCQLHGRRKSKLVTLVTSIFSSAYVYLWPVFDGRRIVEYVTENEIRDYMRWRQVDHINNLYNTCFWTLVKG-GRTAQEANKELSGTISSQKQEMLHTEFGINYNNEPSMFRKGSLV----------- Stehi1 MAGSRFAYVRNFEDPLLP-GTYMVFRLDGHSFHRFSDEHKFTKPNDDRALKLMDHAARAVMDIVLGFGESDEYSFLLRKSTQLYNRRHAKIVTTLTSYFTSSYVFHWPSFDG-RIVLYPSEREVKDYFAWRQVDHINNLYNTAFWALVQG-EMSTKEAHATLSKTVSSEKHEIMHSRFGINYNEVNMRFRKGSVLHCDVI-KDEFW Tapde11 MANSKYEYVRDFEDSLLP-NCAIVIRIDGHSFHRFSAVHDFAKPNDRAALDLMNHAARCVMDITLGYGISDEFSFLLRPSCVTFGRRDSKLVSTVVSIFTGAYIFAWPSFDG-RAVLYPTRQTVVDYFSWRQVDHINNLFNTCFWTLQGGPRKSAQEAEEVLRGTVAAQKNELLWRDYGVNYNDEAEMYKKGSILHVDLI-QESFW Thetr MAKSQYEYVRKFEDALLP-LTWVVIRVDGRGFSGFVARHEYAKPVDTRGAAVMDAAAKAVMDLVLAYGHSDEFSFVLPPSSNVYKRRASKLVSTVVSLFTGAFIAAWPVFDG-RTVVLPTRAVLRDYLSWRQVDHINNLFNTGFWALV---GDDPAVANKLLCDANSAQKNEILFSRFGINYNNEPELNRKGSIWNTDLI-GDAFW Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 --RSRFEYVRNFEDSLLP-NTWIVVRIDGRGFTKMCAKYEFEKPNDRRALDLMNAAAKAVVEITIAYGVSDEYSFVFHKSCNLFERRASKLVSTVVSTFTANYVYLWPTFDG-RAVCYPAVQNLRDYMSWRQADHINNLYNTAFWKLILG-GLDNKEAEKTLAGTLAADKNEILFSRFHINYNNEPEIFRKGT--HIDII-KDEFW Umbra1 MAKSRYEYVKQFEDSALP-GTWMVVRIDGRGFHGFTDMHKFEKPNDLRAIHLMNRAALEVVDIIIAYGQSDEYSFVLPASSTLYSRRISKITSTIVSLFASNYTMHWPCFDA-RLVCYPTQRILRDYLSWRQADHINNLYNTTFWAIV-S-GKSEQEAEEKLRGTFSKDKNEILYSDFNINYNTLDAVYRKGSVIHDDII-GNEFW Ustma22 MAGTKFAYVRNFEDSVIP-STYLVVRIDGKGFHKFSAAHTFAKPNDALALELMNEAARYVMHIALAFGESDEYSFLLRRSTTLYNRRNSKITTHIVSLFTSAYVFSWPSFDG-RMVVYPNEKVVRDYFSWRQADHINNLYNTVFWALVQA-GLTEQEATKRLEGTVSADKHEILHSQFGINYDRLEAMFRKGTTLHCDII-SNDFW Walse1 MANSRFGYVRDFEEKLVP-YSFTVVRIDGQSFHRFSDIHQFEKPNDKRALECMNSAAKFVLDVILAFGESDEFSFLLRPQTTLYDRRKAKILTKVVSAFTSAFVYNWPGFDG-RTVTYPHPKHVRDYFAWRQVDHINNLYNTTFWAIVQG-GKTEREAHKILQGTVSAEKHDILFKEYGINYNTLDDLYKKGSILHLDII-KDTFW Zygro1 MAKSRFEYVRDFEDVLIP-ETYIVVRIDGKKFHEFSNYYKFEKPNDMRALKLMNACAKNVLEVILAYGESDEYSFILRSDTTLYNRRIDKISSLFVSLFTSQYVMLWPFFDS-RCVSYPNLKCIKDYLSWRFVDHINNLYNTVFWQLVKC-GLTTREAENKLSGTVSSEKQEILFSECGINYNNEPEMFKKGSLVHIDVI------ [Cluster2230.fasta_al_trimmed; alignment length = 110] Allma1 PDLRHLDY-DHIYEPAEDTFLFLDALEEICLEIGSGSGCVSTFLAMTDINPRACTATRRTLEPVRTDLAIDVLLFNPPYVPTGGQLGRV-VTDRVLAYLVLLQENKPDEI Ashgo11 PEVK-CDP-ERVYEPSEDSFLLLDCLEKVVCEVGCGSGVVTAFMMQTDVSPWALATTAETLCAARTDLQVDVLVFNPPYVPAGGADGME-VTTRMLAYILFCARNRPEEV Aspfu1 PSTDHVSF-DTIYEPSEDSYLFLDTLSSLVVEVGTGSGVVLAFVAATDVNRNACVATRTTVASVLGDLSVDVLLFNPPYVPTGGLDGME-TTNRLLAYVLLCAQNRPEEV Aurde31 PDLSHLDY-EHVYEPAEDTFILLDALEQICVDIGSGSGCVSAFLGSTDINPHAALCTRRTLCPIVANFKVDILVFNPPYVPTGGHDGMQ-VTNILLFYLVALKQNDIPGI Batde5 PDISHIQY-QSVYEPAEDTFLLLDALEKIALEIGSGSGCVTAFLGATDINDFAAKTTLKTIDAVITSFNIDVLIFNPPYVVTGGIDGRE-VIDKFLCYLVLIKENRPEEI Botbo1 PDLSHLDY-EHVYEPAEDTFILLDALEKLCLEVGSGSGCVSAFLGKTDINLHATQSTLKTLNPVLASLAVDILIFNPPYVPTGGNDGMQ-VTNELLFYLVAVKQNNIPKI Botci1 PDTSHVSF-DRIYEPAEDSFLLLDTLSSLIVEVGTGSGVVLSFVHAVDVNRYACEATQETLGNVVGNLMTDVLIFNPPYVPSGGVDGME-ITDRLIAYILLCAQNKPENV Caeel PQY-RLRA-HDVYEPAEDTFLLIDAIEKLVLEIGCGSGVVSTFVNQTDLNPHALDVTLETIDVVRTDLKVDVLLFNPPYVPTGGRTGRS-TLDRLLFYLVALHSNDIPAL Canalb1 PTVKNIDY-DEVYEPSEDSFLLLDCFEKLVTEIGTGSGIVTTFVAKTDINPHACETVLQTLDSTQMDLEVDLLIFNPPYVPSGGEDGMV-ITWKVLAYILFCARNKPETV Cangl PYVK-CDY-EKVYEPSEDSFLLLDILEKVVCEIGVGSGIVTTFMMQIDVNPWALESTLTTLEPVQADLEIDLLIFNPPYVPAGGEDGMD-VTNKVLAYILFCARNKPEEI Capow PDTSHLGF-EHVYEPAEDTFLMLDALQQVCLEIGPGSGIVTTFLAQVDINTRAAEATAQTVDVLVGDLLVDVLVFNPPYVVTGGLRGRR-VTDRLLFYLLTIDENDPAEI Catan2 PDTPHLPFQDSVYEPAEDTYLFLDALELICLEIGSGSGCVTTFLAMTDINPLATLATLKTVQPILTDLSIDILLFNPPYVPTGGERGRR-VIDRVLAYMVLVDENDPDEI Cioin ------------------------------------------------------------------------------------MHGRE-VMDKFFLYLVVIKENKPDEI CocheC53 PSTSHVCF-DRVYEPAEDSYLLLDTISSLVLEVGVGSGVILAFVAAVDINSFACNAAAHTMDVVNGDLSVDVFIFNPPYVP-GGEDGMV-VTNRMLAYLLLCAQNKPESV Coere1 PDTRHIEY-SSVYEPAEDTYLLLDALENICVEIGAGSGCVTAFLGQTDINPAAVDATIETFFQCRTRFNIDILMFNPPYVVTGGKNGRE-VLDKLLFYLVVIEQNKPDDI Conco1 PDTDHLDF-DQIYEPAEDTFALLDALENICLEIGTGSGCVVSFLGKTDINPLANAGSLSTIDSITCDLKIDVLIFNPPYVVTGGVDGRE-VIDRLLFYLVTIRENKPKEI Conpu1 PDLSHLDY-DRVYEPAEDTFLFLDGLEQVCLEIGSGSGCVSTFMGSTDINQHAARCTVATIDAINCSLSIDILLFNPPYVPTGGLSGME-ITNKLLFYLVALKQNDIPAI Copci PNLSHLDY-DLVYEPAEDTFLLLDALEAVCLEVGSGSGCVSAFLTKTDINPHACRASQATLDVLNGPFSIDVIMFNPPYVPTGGLDGMQ-VTNTFLFYLVALKQNNVPEI Croqu1 PDLSHLDY-RDVYEPAEDTFILLDALEAICVEIGSGSGCVSVFAQKTDINPKALQATNSTPNLIRTSLMIDLLLFNPPYVPTGGPIGMT-LTNHLLLYMVAVKENKPEEI CryneH991 PNISHFDY-EHIYEPAEDSFILLDALDLVCVEIGAGSGVVSAFMSNI-------------LDPIQCNLKVDILLFNPPYVPTGGADGMA-ITNILL----CVQTADAKHV Crypa2 PDTSHVSY-SRVYEPAEDSFLLLDTISSLVVEVGPGSGVVIGFVNAVDVNRFACSATEATLGALSGDLLVDVLIFNPPYVPTGGKDGME-ITDRLIAYILLCAGNKPDEV Debha1 PIVKDIDI-DNVYEPAEDSFLLLDCLEELVTEIGTGSGIVTTFIQQTDINPHACKTVLQTLDSCQMNLTIDMLVFNPPYVPAGGEDGMV-VTWRLLAYILFCARNKPKEV Dekbr2 PDIKITDP-EKVYDPAEDSFLLLDSFEELVVEIGTGSGIVSTFINETDINPYSCASALQTLDAVRCDLLIDVLVFNPPYVPTGGPTGMD-ITNKVLAYILFCARNKPKQV Dicdi PKMDHLDY-KDVYEPSEDSYLFIDSLQKIMLEIGSGSGFVITFLAKTDINPKAAIASSKTLDVLNTSFSIDILLFNPPYVPTGGINGRE-VIDKLLFYIVLVQENKPKQV Dmel PYTDHLDF-EHVYEPAEDSFLLLDALEKLCVELGSGSGVIITALAKTDINPKACNATRRTLDSIRCSLSVDVLLFNPPYVVTGGQDGRR-VTDILLLYLLLLRENKPEEI Enthi PDIIPLETWDNVYKPDIDSYLLMDVLEKTSLEIGVGSGIVSKYVKESDINPYALECTKKV---IKSSLSIDLFIYNPPYVPTGGKDGRE-KIDCVIGYIVIIQDNDPKSI Falba PRVNHFDY-GNFYEPAEDSFLLLDALEAVAAEIGPGSGVVTSFLAAFDINPFAVEATKLTQDVVLGDLSADLLVFNPPYVESGGRDGGAGVARRALFYLLLAQPNRPHEL Fomme1 PDLSHLDY-ERVYEPAEDTFILLDALEKLCLEIGSGSGCVSIFVGRSDINEHASQCTLRTLDPVVTSLGVDLLIFNPPYVPTGGAFGMD-ITDRVLFYLVAVKQNDIPSI Fusgr1 PDTSHVPY-ERVYEPAEDSYLLLDTLSSLVVEVGTGSGVVLAFVHAVDMNAFACRATVGTLGSCMGDLAIDVLIFNPPYVPTGGVDGME-TTDRLIAYLLLCAQNKPDQV Galma1 PDLSHLDY-NEVYEPAEDTFLLLDALETICLEVGSGSGCVTAFIAKTDINPHACRCTRLTIQVVNGSLRIDVILFNPPYVPTGGVDGME-ITNVLLFYLVALKQNNVPRI Ganpr1 PDLSHLDF-RNVYEPAEDTFLLMDAIEEVCLEIGSGSGCVSTFVAKTDVNPHAARATRRTLDPVVTDLSVDLLIFNPPYVPTGGVDGRE-VVDRFLFLMVLLEDNAPEEI Gloin1 PNLDHLDY-ELVYEPAEDTFLLLDALEKICLEIGSGTGCVSTFLGKTDINPYASAITNKTLDSITTNLSIDILCFNPPYVVTGGIDGRE-IIDKMLFYLLLINENKPNEV Hisca1 PSTSHVSF-DTIYEPAEDSYLFLDTLSSLVVEVGTGSGVVLAFVAATDVNSNACSATRQTLSSLTADLSVDVLIFNPPYVPTGGELGME-TTNRLLAYVLLCAQNKPDEV Klula1 PYVS-YDY-NKVYEPSEDSFLLLDALEALTIEIGSGSGIVSTFLMQTDLNPWALDATLDTFDVLQTDLEVDLLVFNPPYVPAGGDDGMV-VTQRLLAYILFCARNKPETV Lacbi2 PDLSHLDY-DRVYEPAEDTFLLLDALELICLEIGSGSGCVSTFLAKTDINFHACRCTFLTLDPINTSLGVDIILFNPPYVPTGGFNGME-LTNVFLFYLVAVKQNDIEHI Lenti61 PDLSHLDF-EHVYEPAEDTFILLDALEETCLEIGSGSGCVTAFLGSTDINPYACKCTKTTIEPLLASLSVDILLFNPPYVPTGGRDGMV-LTDILLFYLVAVKQNDIKGI Malgl1 PEVAHLEYTNEVYDPAEDTFALMDALENLCVEIGSGSGCVSAFVSK------ADELTRKTLHPVVASVAVDLLLFNPPYVVTGGTNGTK-ILDTLIFYVVAIRQNDPHAL Mellp23 PDLSHIDY-DDVYEPAEDTFILLDALEAICVEIGSGSGCVSVFAQKTDINSKALTVTDSTPNLVRTSLSVDLLLFNPPYVETGGANGME-LTNQLLLYLVAIKQNKPEEI Mnele -------------------------------------------------------------------------------------------------------------- Monbr PDYGHV---DEV--------------------------------------------ARETIETYRGDLRLDVLLFNPPYVVTGGAHGRE-VLDRLLFYLIALKENTPDDL Morel2 PDLSHLDY-EFVYEPAEDTFLFLDAFEDISLEIGSGSGCVTAFVGKTDINPKAARATQGTVDIIETHLQIDLMYFNPPYVLTGGIDGRE-VIDEFLFYMVVVNENKPDEI Mucci2 PDLSHIDY-ERVYEPAEDTFLLLDALEEVCLEIGSGSGCVTTLLAKTDINAFACETTRQTIEPIRASLRIDILCFNPPYVVTGGIDGRE-VIDQLLFYLLLINENKPDQV Mydma PFYSHIDF-LSIYEPSEDTFLLIDTLEKICLEVGSGSGVVITFLAKTDINLNACICSKKTVETHCDSFNIDILLFNPPYVLTGGKDGRE-VIDKFLFYIVLIKENKPYEI Neucr2 PDTSHVPY-QRVYEPAEDSFLLLDTLSSLILEVGPGSGVVIAFLTAIDVSPFACAATNLTTSATQGDLSVDVLVFNPPYVPTGGRDGME-TTDRLIAYILLCAQNKPEEV Orpsp11 -------------------------------------------------------------------------------------------------------------- Pench1 PDTSHVSF-DTIYEPSEDSYLFLDTLSSLVVEVGTGSGVVLAFTAATDVNRNACIATWKTISSLTADLSVDVLLFNPPYVPTGGADGME-TTDRLLAYVLLCKQNRPDEV Phybl2 PDLSHLDF-DRLYEPAEDTFLLLDALEELCLEIGSGSGCVTAMLAKTDINPYACKATQQTVETLQTSLSVDVLLFNPPYAVTGGIDGRQ-VIDALLFYLLLINENHPLEV Picst3 PEVKHIDY-DTVYEPSEDSFLLLDCFEQIVTEIGTGSGIVTTFLQKTDVNPHACKTALHTVDICQMDL-IDVLLFNPPYVPAGGEDGMV-ITWKVLAYILFCARNKPDFV Plicr1 PDLSHLDY-DHVYEPAEDTFLLLDALEQICLEIGSGSGCVSCFAGSTDINSHASRCTTLTLDAITASLAVDLLLFNPPYVPTGGTAGMQ-VTDLLLFYLVAVTENDIPGI Polpo PNMSHLDY-QNVYEPAQDSFLFIDALKKVAVEIGSGSGFVISYLSMTDINPIAAMTSTRTLDVVNTSFNVDVLLFNPPYVPTGGIDGRE-VIDKLLFYIVLVEENKPAEV Pucgr2 PDLSHLDF-QHVYEPAEDTFILLDALEAICLEIGSGSGCVSVFIQQTDINQLALKATASTPNVIQTSLTIELLLFNPPYVETGGSDGMK-LTNQLLLYIVAIKENKPDEI Punst1 PDLSHLDF-DEVYEPAEDTFLLLDALEEICLEIGSGSGCVSSFLSTTDINPHAARCTVATLDSVNTWLAVDVLLFNPPYVPTGGTDGMQ-VTDLLLFYLVALKQNNIPRI Rhior3 PDLSHIDF-ERVYEPA-------DALEQFCLEIGSGSGCVTSLLAKTDINPFACQITRQTIEPIQTSLSIDIFCFNPPYVVT--------------FFA----------- Rhoto1 PITSHLDF-ENVYEPAEDTFILLDALEQVCLEIGSGSGCVSAFLGATDLNPHACRCTLLTLNPILTDLQVDVLVFNPPYVETGGVGGMR-VTNRVSFYLVAVPENKPLAI Rozal11 LDLSHIDK-TKVYDPDDDSFLMGDTLINVCVEIGCGSGAVITILHETDINLNALNCTKKTVETIRTDLKPDVVVFNPPYVVTGGYKGRV-VIDRFLLYLLLIQPNDVDEV Sacce1 PYVK-CDY-DKVYEPAEDSFLILDCLEKIVCEIGSGSGIVTTFLMQVDINPWALEATLDTLEVIQADLQVDVLIFNPPYVPAGGKDGMA-ITDKLLAYILFCARNKPKEV Salro PEYGKV---DSVYEPAEDTFLLIDGLEALCVEIGSGSGVPITSLACVDINPDAVMCTQDTAECLQGDLKADILIFNPPYVVTGGADGRE-VIDRFLLYMIALQENSLDSM Schco3 PDTSHLDF-ESVYEPAEDTFLLLDALEAVALEIGSGSGCVSAFLGKADINLHACKCTRQTLEPINASFSVDILLFNPPYVPTGGTDGMQ-VTDLFLFYLVAVKQNNIQDI Schpo1 PVTSQLEF-QDVYEPAEDTFALLDALEKLTAEIGCGSGCASSFLKSSDISNSACRASKITFITVQTSFGVDILIFNPPYVPTGGTDGMD-VTSTLLFYMVAVARNKLHSI Sorma PDTSHVPY-NRVYEPAEDSFLLLDTLSS----LGPGSGVVIAFLTAIDVSPFACAATDLTTSPIQGDLSVDVLVFNPPYVPTGGKDGME-TTDRLIAYILLCAQNKPEEV Sphar PDVGHLDF-DFVYEPAEDTFLFLDALEKIGLEVGSGSGTVITFLATTDLNDKAAAATYTTVEVLRTDLQVDVLLFNPPYVPTGGKDGRE-VTDRLLFYLVVLPENKPDEI Spipu1 PTLSHLDY-QHVYEPAEDTFLFLDALEAVSLEIGCGTGIITTFLQTTDINPQACKATAATVDAIRTDLGIDILLFNPPYVVTGGKDGRE-VVDRVLFYLVTIRENKPQEI Sporo1 PSTSHLDF-ESVYEPAEDTFVLLDALEQLCLEIGSGSGCVSAFLGATDLNPHATRCTLETLDPILTNLQVDVLVFNPPYVETGGESGMK-ITNKVLFYLVAIPQNKPLEI Stehi1 -------------------------------------------------------------------------------------------------------------- Tapde11 -------------------------------------------------------------------------------------------------------------- Thetr PEYSHLSFKENVYPPSEDSFLLLDSVLATVLELGAGSGFVLAGVAMVDVNSVALEATRTTLQCVQADALAHVLLFNPPYVPTGGIRGRE-VLDQALAYLLLLAENDPPEV Treme1 PIISHLDY-EHVYEPAEDTFILLDALEALCGEIGSGSGIVSTFLYHTDINLYACSTTIRTSDPILCSLQVDLLIFNPPYVPTGGKAGME-ITDIILFYLVAVEPNDPPAI Trire2 PDTSHVPY-ERVYEPAEDSFLLLDTLSSFVVEVGTGSGVVLAFITAVDMNAFACRATVTTLGSVMGDLSVDVLVFNPPYVPTGGADGME-TTNRLIAYVLLCAQNKPELV Umbra1 PDLSHLDF-RNIYEPAEDTFLLLDALEQICLELGSGSGCVTTFLGSTDINPHAAVATVATIDTVETSLSIDVLCFNPPYAVTGGIDGRE-VIDATLFYLLLVSDNKPDEV Ustma22 PSLSHLDF-RSVYEPAEDSFILLDALEAICVEIGSGSGIVTTFISQIDLNAHANTCTRATIEPVRTSLQVDVLLFNPPYVPTGGETGTK-LVDELIFYLVAIKQNNPVSL Walse1 PDLSHLDY-DKVYEPAEDTFILLDAIEELCYEIGPGSGCVSAFIASSDINPYAASCTRRTLDVIQASLSVDLLLFNPPYVPTGGNIGMD-LTNKVLMYLVAIRQNNPQDI Zygro1 PYIK-CDY-ETVYEPCEDSFLLLDGLEQIVCELGPGSGIVTTFLMQLDISPWALEATQDALSVIQSDLSTDLLVFNPPYVPAGGEDGMV-ITRQVLAYILFCARNKPEQV [Cluster2231.fasta_al_trimmed; alignment length = 77] Allma1 SVFKTLVVVELKNDLAIQGTLVSVDQYLNIKLDHVSAVDSARYPHVATLKNSFIRGSVVRYVHLPIDTALLQDATRN Ashgo11 SFFKTLVTVELKNDIELKGTLKSVDQFLNLKLDNISCNNEAKYPHLSSVRNIFIRGSTVRYVYLKVDTNLLQDAARR Aspfu1 SFFKTLVTIELKNDIRIRGTLKSVDQYLNIKLDDVDVLDLDKYPHLSSVKNMFIRGSVVRYVMLPVDVGLLEDATRR Aurde31 PYSKTLVTVELKNDLCITGVLKSVDQFLNIRLDSIKVLDEARHPHM-ALKNCFIRGSVVRYVQLPVDTQLLEDATRR Batde5 SFFKTLVIIELKNDLAIVGKLVSVDQFLNFKLDNIRVEDEERFPHMMSVKNCFIRGSVVRYVRIPVDTALLQDAARK Botbo1 SVFKTLVTVELKNDLCIKGTLKSVDQFLNIRLDAIQVLDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Botci1 SFFKTLVTVELKNDIQIKGILKSVDQYLNIKLDDIQVVEELKYPHLSSVKNVFIRGSVVRYVHLPIDTALLEDATRR Caeel -----------------------------MKLTDITVSDPERFPHMVSVKNCFIRGSVVRYVQLPVDTQLLADSCRK Canalb1 SFFKTLVTVELKNDIEIKGTLKSVDQFLNLKLDNITCTNGQRYPYLGAVKNLFIRGSNVRYVHMNVDCTLLQDASRR Cangl SFFKTLVVVQLKNDIEIKGTLQSVDQFLNLKLDNISCNDDKKYPHLSSVRNIFIRGSTVRYVYLNVDTNLLQDATRR Capow SFFKTLVVVELKNDLCITGTLHSVDQFLNIKLLDISVAEPEKYPHMVSVKTCFIRGSVVRYVRLNVDTELLQDASRR Catan2 SFFKSLVTVELKNDMSIKGTIQSVDQFLNIKLDKVQVQDTARYPHVMTLKNCFIRGSTVRYVHLNVDVQLMQDATRR Cioin SFFKSLVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFVRGSVVRYVQLPVDTGLLQDAARK CocheC53 SFFKTLITVELKNEVQIRGTLKSVDQYLNIKLDNAEAVDELRWPHLCSTKDMFIRGSVVRYVHLPVDTALLEDATRR Coere1 SFFKTQVTVELKNDLAIQGVLESVDQFLNIKLKEIKVVDSERYPHMMAVKNCFIRGSVVRYVQLSVDTALLQDAARR Conco1 SCFKTLVTVELKNDLAIQGTLATVDQFLNMKLNDIKVIDEVNYPHLISVKSCFIRGSVIRYVQLPVDTALLQDATRK Conpu1 SVFKTLVTVELKNDLSITGVLKSVDQFLNIRLDSITVLDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Copci SVFKTLVTVELKNDLMITGVLKSVDQFLNIRLDNIKVSDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Croqu1 SVFKTLVTVELKNDLAIQGTLASVDQFLNLKLENIKVLDQERHPHMMAVKNCFIRGSVVRYVQIPVDTQLLEDATRK CryneH991 ----------------------------------------------MAVKNCFIRGSVVRYVRMAVDTTLLEDATRR Crypa2 SFFKTLVTVELKNDIKITGTLKSVDQYLNIKLEDIAVQEELKYPHLSAVKNVFIRGSVVRYVHLPVDVTLLEDAARR Debha1 SFFKTLVTVELKNDIEIKGILKSVDQYLNLKLDNISCVNESKYPHLQSVKNLFIRGSTVRYVHMNVDCTLLQDASRR Dekbr2 SFFKTLITVELKNDVKITGTSRSIDQFLNIKLDNIET-DVEKYPHFKAARSIFIRGSAIRYIHLKVDTNLLQDASRR Dicdi SFYKSLITVELKNDLSITGLLQSVDQFLNIKLKDIKVNEEDKYPYMISVKNCFIRGSVVRYVHLPVDVETLQDHSRL Dmel SFFKSLVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPDKYPHMLSVKNCFIRGSVVRYVQLPVDTQLLQDAARK Enthi --------------------------MLNIKLNNLKC-DATLFPQIQTMTDCFIRGNTIRYVSMAIDVQLLHDATLL Falba SFFKTLVAVELKNGVVIRGDLTSVDQFTNLKLENIQVVDDHLYPHMSSVSSCLIRGSVVRYVHLRVDCDLLQDATRR Fomme1 SLFKTLVTVELKNDLSITGVLKSVDQFLNIRLDNIKVLDEANHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Fusgr1 SFFKTLVTVELKNDIQLKGILKSVDQYLNIKLDDIQVVEELKYPHLSSVKNVFIRGSVVRYVHLPVDTQLLEDATRR Galma1 SVFKTLVTVELKNDLSITGVLKSVDQFLNIRLDNIKVADETRHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Ganpr1 SFFKTLVTVELKNDLALSGTLVSVDQYLNIKLDAVSVQDEQKFPHMMAVKNCFIRGSVVRYVSLPVDTALLQDAARR Gloin1 SFFKTLVTVELKNDLAITGILKSVDQFLNIKLDEIRVVDDTKYPHMMAVKNCFIRGSVVRYVQLPVDTALLQDAARR Hisca1 SFFKTIVTIELKNDIRIRGTLKSVDQYLNIKLDDIEVLDLDEYPHLSSVKNIFVRGSVVRYIVLPVDRGLLEDATRR Klula1 SFFKTLVKVELKNGIELTGTLKSVDQFLNLKLDNISSNNNEKYPHLSSVRNMFIRGSTVRYVHLKVDTNLLQDATRR Lacbi2 SVFKTLVTVELKNDLSITGVLKSVDQFLNIRLDNIKVSDESRHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Lenti61 SVFKTLVSVELKNDLSITGTLKSVDQFLNIRLDNIKVQDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Malgl1 SAFKTLVTVELKNDLAIQGTLKSVDQFLNFKLDDIKVLDEARYPHMLAVKSTFIRGSVVRSVHIPVDTQLLEDATRR Mellp23 NVFKTLVTIELKNDLAIQGTLASVDQFLNLKLENIKVLDQERYPHMMAVKNCFIRGSVVRYVQIPVDTQLLEDATRK Mnele SFFKSLVIVELKNDLSICGTLHSVDQFLNIKLTDISVSDSDKYPHMLSVKNCFIRGSVVRYCHIPVDPALLMDATRK Monbr SFFKTLVTVELKNDLQLNGVLKSVDQFLNIKLDSIQVADIERYPHMMAVKNCFIRGSVVRYIHLPVDKQLLQDATRK Morel2 SFFKTLVTVELKNDLAITGVLVSVDQFLNIKLDNIKVVDEERYPHMLAVKNCFIRGSVVRYVQLPVDTALLQDAARR Mucci2 SFFKTLVTVELKNDLAITGVLKSVDQFLNIKLDDIQVVDEERYPHMASVKNCFIRGSVVRYVQLPVDTHLLQDAARR Mydma ----------------------------------------------------------------------------- Neucr2 SFFKTLVTVELKNDIQIRGVLKSVDQFLNIKLDNIQVVEELKYPHLSAVKNVFIRGSVVRYVHLPVDIQLLEDATRR Orpsp11 SFFNTLVTVELKNDLTITGKLVSVDQFLNIKLNDISVLDQQKYPHMDSVKSCFIRGSVVRYVSLSVDTALLQDATRR Pench1 SFFKTLVTIELKNDIRIRGILKSVDQYLNIKLDDIEVLDLAKYPHLSSVKNMFIRGSVVRYVMLPVDVGLLEDATRR Phybl2 SFFKTLVTVELKNDLVITGTLKSVDQFLNIKLDDIQVIDEDRYPHMISVKNCFIRGSVVRYVQLPVDTALLQDAARR Picst3 SFFKTLVTVELKNDIEIKGTLKSVDQYLNLKLDNISCVNGTNYPHLHSVKNLFIRGSTVRYVHMSVDCTLLQDASRR Plicr1 SVFKTLVTVELKNDLSITGVLKSVDQFLNIRLDSIKVLDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Polpo SFYKTLITVELKNDLSITGLLQSVDQFLNIKLKDVRVEEEDKYPYMLSVKNCFIRGSVVRYVHLPVDVETLQDHSRL Pucgr2 SVFKTLVTIELKNDLAIQGTLASVDQFLNLKLENIKVLDQERHPHMMAVKNCFIRGSVVRYVQIPVDTQLLEDATRK Punst1 SVFKTLVTVELKNDLCITGTLKSVDQFLNIRLDGISVLDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Rhior3 ----------------------------------------------------------------------------- Rhoto1 SVLKTLLTVELKNDMAIRGQLKSVDQFLNIKLDNIRVLDEERYPHMIAVRNCFIRGSTVRYVQLPVDTQLLEDATRR Rozal11 SRMKILITIELKNDIAIKGVLNSVDQFLNLKLDDIEVLEKEKYPHLWSVRNIFIRGSVVRYVALPVDTELLQDATRR Sacce1 SFFKTLVVVELKNDIEIKGTLQSVDQFLNLKLDNISCTDEKKYPHLGSVRNIFIRGSTVRYVYLNVDTNLLQDATRR Salro SFFKTLVVVELKNDLSIQGTLTSVDQFLNIKLDDITVGNVDKYAHMVSVKNCFIRGSVIRYIQLPVDTQLLQDATRR Schco3 SVFKTLVTVELKNDLSITGVLKSVDQFLNIRLDDIKVLDEARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Schpo1 SFFKTLVTVELKNDMSIRGILKSVDQFLNVKLENISVVDASKYPHMAAVKDLFIRGSVVRYVHMSVDTILLADACRR Sorma ----------------------------------------------------------------------------- Sphar SFFKTLVVVELKNELKIQGKLHSVDQFLNIKLKDITVENVEAYPHMVCISNTF------------------------ Spipu1 SFFKTLVTVELKNDLEIRGTLVSVDQFLNIKLDDVHVVDEQKYPHMMSVKNCFVRGSVVRYVSLPVDTALLQDAARR Sporo1 SLLKTLLVVELKSDLKIRGTLISVDQFLNIKLDNISVLDEERYPHMAAVRNCFIRGSVIRYVQLPVDTQLLEDATRR Stehi1 SVFKTLVTVELKNDLSITGTLKSVDQFLNIRLDQIEVMDPARHPHMMAVKNCFIRGSVVRYVQLPVDTQLLEDATRR Tapde11 ----------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------- Treme1 -FFKTLITVELKNDLCITGTLKSVDQFLNIRLDGITVEDPERHPHMMAVKNCFIRGSVVRYVRMGVDTTLLEDATRR Trire2 SFFKTLVTVELKNDIQLKGILKSVDQYLNIKLDDIQVVEELKYPHLSSVKNVFIRGSVVRYVHLPVDTQLLEDATRR Umbra1 SFFKTLVTIELKNDLAITGTLVSVDQFLNIKLDNIKVVDEARYPHMITVKNCFIRGSVVRYVQLPVDTALLQDAARR Ustma22 SAFKTLVTIELKNDLAIQGTLKSVDQFLNFKIDNIRVLDEAKHPHMMAVKSAFIRGSVVRYVHIPVDTQLLEDATRR Walse1 SVFKTLVTVELKNDLCLIGTLKSVDQFLNIKLDNVKVLDEQRYPHMMAIKNTFIRGSVVRYVQLPIDTQLLQDATRR Zygro1 SFFKTLVVVELKNDIELKGTLKSVDQFLNLKLDNISCTDQTKYPHLGSVRNIFIRGSTVRYVYLNVDINLLQDAARR [Cluster2247.fasta_al_trimmed; alignment length = 171] Allma1 -----------VSLSAFAFLFSELVQYSQKHV-KGIQDLEKRLNLVGYRVGQRLLELLVFRSKRDVKLLNALLFINTNVWKALFGKPADSLEKS-SEDEYMISDNDLVVNRYISIPKEMSQLNTGAFIAGIVEAMLDGSGFPAR-VTAHTVPPFRTTILIKFDVMDREKRL Ashgo11 LYAESLAPKHQVSLSAFTFLFQEMVVQQRDSS-KTVAEIEAKLNALGYAIGMRLVELLPFRKKRPLKILDILQYVHGPLWRYLFGAASDDLVKS-SENEYMIVDNEPQWTQFIH----GTSIQCESFTGGIIEGVLDHAGFPCH-VTVHTDPDQRTVYLIQFKVVEREYLR Aspfu1 IYDRHLNRSRELSRASFAFLFAEMVTYAQRRV-TGIQDLERRLNEQGYPLGLRLLDLLFYRPNRPLRILPLLHLIHGPLWRLLFQRPADALEHS-VSNEYMITDNDPLVNTYISVPKEMNMLNCAAFVAGIIEGVCDGCGFEAK-VTAH---PGRTIFLLRFGVMEREKVL Aurde31 IYDRNLNKTREVSLSAYAFLFSEIVQYTLKRV-NGIADLERRLNVLGYRIGIRVFELMSWRPKREIRFLPALMSIHTQFWRAVFGKPADGIEKS-VEDEYMIIDNDPPITRFISIPRDMNQLSCSAITAGMVEAVLDGLGFPAR-VTAHSVPPQRTTILIKLDVLEREEAL Batde5 ILDRNLNRTREVSLSAYAFLFSEMLQYAQKRV-NGIQDLEKKLSDFGYRVGVRMLEFILWRAKRETRILGALYFINTAVWKTLFGKQADSLEKG-TDDEYMISDNEPLITKYISVPREMSSLNCGAFTAGVVEAILDGCQFPAR-VSAHSTGPSRTTILIKFDGKYNATKL Botbo1 IYDRNLNKTREVSYSAFAFLFSEAIQYTQKRV-SGIADMERRLSTLGYRVGIRVLELMSWRPKREIRLLPALSYIHTQVWKTLFGKPADAIQKS-VEDEYMIVDNDPPITRHISIPREMSQLNCSALTAGIVEAVLDGLGFPAR-VTAHSMPPSATVILIKLDVVEREEAL Botci1 IYHRPLNRSKELSQASFAYLFGEMVSYAQRRV-TGIQDLEKRLNVQGHPIGLKLLDLLLYR--RPLNIIALLQFITTVLWRHLFSRPADALEKS-SNEEYMISDNEPLVNQYISVPKEMNQLNCAAFVAGIIEGVCDGAGFPAR-VTAHSVGPGKTVFLVKFQVVEREAFL Caeel ILDKSLSRGKEINLSTFAVLFSEMVLYAQNRS-ETVTDIHDKIASYGKQVGLRMFDIITLRYKRETKLLGMLMFIKSTVWKNLFGKEADKLERS-NDCTYLLIEKDPMVNTYISVPRDKGVLNCAAFAAGIVEAILESASFKCK-VTAH---HNGTAYVIQFDVIARENSL Canalb1 IYDRNIITKKEINLSSLSFLFCEIISWAHSNS-KGIQDLENRLNGLGYQIGQRYLELCKIRSKREIRLLEMLQFIHGPFWKLIFGKTANELEKS-QDNEYMIVENVPLLNRFISIPKEYGDLNCSAFVAGIIEGALDNSGFNAD-VTAHTVAPLRTVFLIKFDVLIRESLR Cangl IYNESLIFKKEVSLSAMTFLYQEMISNIHNDC-KDINEFETRLSKMGYNIGLRLIELLNFRRRRDLKILDVLQFIHGSLWSYLFGHVSNDLVKS-SENEYMIVDNKPKLTQFIS----GKNVSCDYFVCGIIHGYLTSAGFPCK-VTPHSMPDNRVVFLIQFDVLEREGLR Capow IVDRPLSRGKEVSISAFAFLFSEIIQYCQGRV-ESNTGLERKLSEIGRRVGIRMFELLNGRAKRETRLINILHFINSVVWKTLFGKPADLLEKAQSEDTYMISDKDLLVNRFISVPKDYG-LNCAAFVAGVVEAILEGAMFPAR-VSAHT--ENGTTILIEFEVIARERQL Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ILDKPTSRGKEVSLSAFALLFSEMIQYSQNRV-RSVAELQTKLSDFGFSVGSRLVDLLIVRNKREIKVLNILLFIKVQLWKALFGKEADKLEQA-SDKIYYIIEKEPVISTYISVPKDKGSLNCAAFAAGIVEAVLNFSNFPCK-VTAH---HKGTTLMIKFDVIARDKLV CocheC53 IYDRNLNRSKELSRAAFAYLFIEMIAYAQKGA-KDVGGLEQRLNSQGYPIGLRLLDLLLSR--RPTRILPLLQFIAQQLYRYLFGRPADALEKS-GTGQYMLFDNEPMVNQYISLPKELSSLNCAAFVAGIIEGVCDGAGFPTEGVTAHSVGPGKTVFLIKFKVLEREEIL Coere1 LLEQSTAKPRKVGLGAFAFLLAEIIRYSQNRV-LGIQDLEAKMNEIGKRVGIRVFELMMWRVHRETRVLQTLVFINTVVWRALFEKQADSLGRS-TEDEYMITDNEPAVLKYISVPKEMSSFSPGAFLAGIVEAIAECCQCPAR-VTSHLVPPLKTVILLKFDVMDREKRL Conco1 ILDRPFNKLREVSLSSFAFLFSQIIQYSQLKV-TGITDLENNLNKIGQRVGIRTLELIMSRIRRELTIINQLYFINTTVWKYLFGKAADSLEKS-TDDEYMISDNDPYLTQFISVPKDLSQLNCNAFLAGIIEGVLRASQFPCR-VTAHSNPPKRTTILIKFSVLHRDNLQ Conpu1 IYDRPINKTREVSLSAFSFLFSEMIQYTQKRV-SGINDLERRLNALGYRVGLRVLELLAWRPKRETRFLPALMFVHTQVWRAVFAKQADAIEKS-VEDEYMIVDNDPPLERHISVPRDMSTLSCSSFAAGIVEAVLDGLNFPAR-VTSHATPPHRVTILIKLEVLAREEVL Copci IYDRPLNKTREVSASAFAFMFSEIVQYTQKRV-NGINDLERRLNTLGYRIGMRVLELMIWRPKREIRLLPVLMMIHSQVWKAVFGKAADAIEKS-VEDEYMIIDNDPIIERHISVPRDLSQLSCSSFTAGIVEAVLDGLGFPAR-VTAHNTPPSRTTILIKLEVLEREELF Croqu1 ---------------AFEFLFAEIVRYTQKRV-DGIGEFEKKLNSLGYHVGTRLLALLSLRPPRLTRLVPVLSWIHTTVWKTVVGKTADVLEHS-NEDEYMISDNDLLLIRAITIPKEMSQLSCGAIMAGVVEGCLDGLGFPAR-VTSHSAPPKRTTLLIKFEPIER---- CryneH991 IIDRPLAKTREVAMGAWAFMFAEIVAYSQSRV-DSVSDLEARLSSLGYDAGQRLLPLLLLRPKREHRLIPILQFIHTQVYRYCFGRAADGLERS-VENEYMITLNQPPLTQFISVPKDMSQLSCEAYTAGIVEGVLDGLDVPAR-VTAHTVPPQRTVILIKLDVMDREEAL Crypa2 IYSRTLNRTRELSQSSFAYLFSEMVSYAQKRV-TGIQDLEKRLNLQGHPIGLKLLDLLLYR--RPRDIITLLHLIKIQMWTHLFGRQADRLEKS-SNDEYMIIDNEPLVNAYISVPREMSQLNCAAYVAGIIEGICDGAGFPAR-VTAHSVGPGKTVFLVKFAVLEREAYL Debha1 IYDRNL-NKKEISLSSLSFLFCEIVNWSHKNS-KGIQDLELRLNGLGYQIGQRFLELVKLQGKREVKIIEILQFIHGSLWKCVFGKTANELEKS-QDNEYMITDNSPLISRFISIPKDYSNLNCSAFTAGIIEGALDSAYFNAT-VTAHSVPPLRTVFLINFDLFIREELR Dekbr2 IYDRNLHRGMEISLSSMSFLFMEVIRMSLNGS-ESSLQMERKLNNLGYRVGLRLLELVSLRAQRHVRVLEILQFVKESIWPCMFGKEADNLEKS-VQNQYMIIDSDPILSRYICVPKEYEGSDCESFVAGIVEGLLDISYFRCE-VTAHSAPPNRTVYLVDFDIISREERL Dicdi IVDRPLSKGKEINISSFAFLFSEMIQYCQDRI-KAGHELEKKLSDMGYSIGPRLLELLCVRSKRETKLLGILSFIHTTVWKSLFGKPADSLEKS-TEDEYMISDNNMVVNKFISLPKHLSSLNCAAFVAGIIEGILCSAEFPAR-VTAHNVAP-KTVILIKFNVIERNA-- Dmel ILDRPLSKGKEVSQSIVALLFSEIVQYSQSRV-FTVPELQTRLHDLGQDVGTRIIDLYFVRSKRETKLTQMLLFVKTTVWKNLFGKEAEKLEHA-NDRTYYIIEKEPLVNTFISVPKDKGSLNCANFTAGIVEAVLTNCGFPCK-VTAH---HKGTTYMVKFEVIARDKQM Enthi ITEKGIPKGTQVSLSGFSFLFAEYVRFRKDNK-QTTTEFHEKLFDLGFNIGMRMLEVINIRNERDINMDNVVGFIAKDMWRVMFGYGVD-VGRV-KGNEFLITDKNLIITEFMSYGNE-KNIYCVAYVAGMAQACIDGADF----NVNYGED-----------IIFQQ--- Falba PAQRSVRKGPRVSLAALAFLFSEIVKMANEAG-GGIEKIEQRLFEVGYSVGIRAVELAYIRLLRSTTIVEILQIIQTVLFPMLYGTRLGPIERD-TSNHYYLIDDDPVVSQFISVPADMKDLNCGAYNAGIIAGFLERAQFPAS-VSAHNHAPSRTVYMVMFEVHDRCKRL Fomme1 VYERNLNKTREVSLSAYAFLFSEIVQYTQKRV-SGISDLERRLNVLGYRIGTRVLELMSWRPKREIRFLPALMSIHTQVWRTVFGKPADAIEKS-VEDEYMIIDNDPPITRYISVPRDMSQLSCSSLTAGIVEAVLDGLCFPAR-VTAHNTPPSRTTILIKLEVMEREEAM Fusgr1 IYHRPLNRTKELSQASFAYLFGEMVTYAQKRV-KGIQELEQRLNLQGHSIGLKLLDLLLFR--RPLGIIQLLHFIKQNIWQHLFGRQADRLEKS-ANDEYHIIDNEPLVNQYISVPKEMSQLNCAAFVAGVVEGVCDGADFPAR-VTAHTVGPGKTVFLVKFRVLEREGFL Galma1 IYDRNLNKTREVSAAAFAFLFSEVVQYTQKRV-SGINDLERQLNTLGYRIGARVLELMLWRPKREIKLLSVLMMIHTQVWKAVFGRPADAIERS-VEDEYMIIDNDPLIERHISVPRDMSQLSCSSFTAGIVEAVLDGLSFPAR-VTAHNTPPSKTTILIKLEVLEREELL Ganpr1 ILDRTLSKGHEVGISAFAFLFSEMLQYSQKRV-NGIQDLERKLADFGYRVGIRALELITWRGKRETRVLNVLYFVHSVMWKSLFGKQADSLEKS-TDDEYMISDNDPVVTRYISVPREYSSLNCGAFIAGIVEAVLDGSQFPAR-VSAHSNPPGRTTLVIKFDVMEREKDA Gloin1 IVERNLNKTKEVGLGAFAFLFSEMLQYAQKRV-HGIQDLERKLNDFGYRVGTRLLELIVWRSKRETRVLGILYFIHTTVWKTLFGKQADTLEKS-TENEYMISDNDPLISKYISVPKELSELNCNSFLAGIVEAILDGAQFPSR-VTAHTLPPLRTTIFIQLDILQREDQL Hisca1 IYDRNLNRTRELSKASFAYLFSEMVVYAQRRV-TGIQDLERRLNEQGYPLGLRLLDLLLYRPIRPLRILPLLHLIHGPLWRLLFSRPADALEHS-VSNEYMITDNDPLVNTYISVPREMNMLNCAAYVAGIIEGVCDGCGFEAK-VSAH---PSRTVFLVRFGVMEREKML Klula1 IYGQSLISKEQVSLSAYAFLFQSIVSYHRDSS-KNVQEIERKLNSSGYTIGMRLTEILNFRKRRNLKILETLQYIHLTVWQYLFSRPSNDLVKS-SENEYMIIDNEPTISQFIQ----HTSVQCESFTCGIIEGFLDMAGFPCH-VTSHFVESNRTVYLIQFDVVERENLR Lacbi2 IYDRNLNKTREVSASAFAFLFSEVVQYTQKRV-NGINDLERRLNTLGYRIGTRVLELMVWRPKRETRFLPALMSIHTQVWKAVFGKAADAIEKS-VEDEYMIIDNDPPIERYISVPRDMSQLSCSSFTAGIVEAVLDGLGFPAR-VTAHNTPPSRTTILIKLEVLDREELM Lenti61 IYDRPLNKTREVSSAAFAFLFSEIVQYTQKRV-SGINDLERRLNTLGYRIGTRVLELMAWRPKRETRFLPALMSIHTHVWRAVFGKPADAIEKS-VEDEYMIIDNDPPITRNISVPRDMSSLSCSSFTAGIVEAVLDGLGFSAR-VTAHNTPPNRTTILIKLEVLEREEAL Malgl1 VLDRPRDKTREVSHSALQFLFAEMVIYAQGRV-SGISEFEQLLGSMGRQVGLRALAMQTQRPQRETRLLKTLLWVHSTLWKAVFGVQADNLERS-TEDEYMITTNVPLFSRGISVPKEMTQLSVEAYAAGIVEGALDGLGFHV---------------------------- Mellp23 ---------------AFEFLFSEIIRYTQSRV-DGIQEFEKKLTILGYHIGIRFLSLLNIRPPRLNRLVPILSWIHTTLWKNVVGKTADILEHS-NEDEYMISDNCLLLTKSITIPKDMSQLSCGAIMAGVVEASLDGLGFPAR-VTSHSAPPNRTTLLIKFESMQR---- Mnele IRDLVLARG-QLILAPRFLNFIEIVQYAMRGS-HKFGSVTNTLLDLAYE-NCKDIDFTKVKPKRENKLINTLLFLKGSVWKSLFGKEADKLERA-DDKTYLIIENEPLVNRYISVPKDKSSLNCAAFMGGIVEALLNHSGFPCK-VTAH---HKGSTLLIKFEVMQRENAI Monbr ILERSLTRPRDINLHAFALLFAEIVRYLYRRFGTSTEEFERRLSALGRQVGDRFGELFVIRNKRELKPINQLIQIQTNLWK------------------------------------------------------------PCS-VVAHGAE----IFVITLDRIAPEALD Morel2 -----------------------MLQYTQKRV-NGIQDLERKLNELGYRVGIRALDLLVWRSKRETRVLGMLYFIHTTVWKTMFGKQADSLEKS-TEDEYMISDNDPMVSKFISIPKDVSQLNCGAFMAGIVEAIMDGCQFPSR-VTAHTVPPLRTTILIKLDVLDREEQL Mucci2 ILEKNLNKSKEVSLSAQTFLFSEMLQYAQKRV-NGIQDLERKLNEFGYRVGSRVLELLAWRAKREIKVINVLYFIHSTVWKALFGKQADSLEKS-TEDEYMISDNEPVLTRYISVPKELSQLNCNAFVAGIVEAVLDGCQFPAR-VTAHTVPPQRTTILIKLDVLEREELL Mydma ILDRPLSKGKEVSISAYGLLFSEIVQYCQSRV-FTVTELQDKLASFGKTIGVRLIDTLSIRFRRETRLLNVLMFIRSSLWKTLFGREADKLEHA-NDGTYYIIEKESLVNRFISVPKDKGSLNCASFTAGILEGIFNGCGFPAT-VTVH---HKGTTFLIKFDVVAREKVF Neucr2 IYHRPLNRTKELSKAAFAYLFAEMVSYAQRRV-TGIQELEKRLNLQGHPIGLKLLDLLLFR--RPLNIIALLHFIKINVWTHLFGRQADRLEKS-SNDEFMIIDNEPLVNAYISVPKEMSQLNCAAFAAGIIEGVCDGAGFPAR-VTAHTVGPGRTVFLVKFQVLEREALI Orpsp11 ------------------------------------------LSDFGYRVGIRVVELLNWRGKREIKILQNLYFIHTNVWKMLFGKQADSLEKH-TEDEYMISDNEPIITKYISVPKDYHSLACGAFLAGIVEAILDGAQLPAK-VEAFANPPTKTTIVINFDVIDREKLF Pench1 IYDRHLNRSRELSRASFAFLFGEMVTYAQRRV-TGIQDLEKRLNEQGYPLGLRLLDLLFYRPNRPLRIITLLHLIHGPLWRLLFGRAADALEHS-VSNEYMITDNDPMVNTYISAPRDMSMLNCAAYVAGIIEGVCDGCGFETK-VSAH---PSRTVFLVRFGVMEREKVL Phybl2 ILERSLNKTREVSLNAQSYMFSEMLQYAQKRV-NGIQDLEKRMNEFGYRVGTRLLELLSWRPKRETRVLGVLYFIHSVVWKALFNKQADSLEKS-TEDEYMISDNEPLLTRYISVPKELSQLNCNAYVAGIVEAVLDGCQFPAR-VTAHTVPPQRTTILIKLEVLQREELL Picst3 IYDKNVSSKKEISLSSLSFLFCEIVNWSHKNS-KGIQDLETRLNGLGYQIGQRFLELTKLRSKREIRIIEVLQFIHGSFWKSIFGRAANDLEKS-QDNEYMIIDNAPLVSRFISIPKDYGNLNCSAFMAGIIEGALDSASFQAD-VTAHSVPPLRTVFLIKFHLMVRESLR Plicr1 IYDRSLAKTREVSASAFAFLFSEVVQYTQKRV-SGINDLERRLNTLGYRIGTRVLELLSHRPKREIKFLPALVSVHGQVWRAVFGKGADAIEKS-VEDEYMIIDNEPVVERYISVPRDMSQLSCSSFTAGIVEAVLDGLGFPAR-VTAHNTPPTRTTILIKLEVLEREEVL Polpo IVDRPLSKGKEINLSSFAFLFSELIQYSQDRI-KAGHELEKKLSDIGFLVGTRVLELLVVRAKRETKLLGILSFIHSTVWKALFGKQADSLEKS-TEDEYMISDANMIVNKFISLPKNLSSLNCAAFVAGIIEGILCSAEFPAR-VTAHNVAP-KTVILIKFNVIPRT--- Pucgr2 VPSRHISTSTDVNLVAFELLFAEIVRYTQQRV-DGIGEFEKKLNILGYQVGSRLLSLLSLRPIRLIRLVPVLSWIHSTLWKTVVGKAADVLEHS-NEDEYMISDNDLLITRAITIPKDMSQLSCGAYMAGIVEGALDGLGFPSR-VTSHSAPPKRTTLLIKFECIDREKTF Punst1 IYDRNLNKTREVSASAFAFLFSEVVQYTQKRV-AGINDLERRLNTLGYRCGMRILELNVWRPKREIRFLPALMFIHTQTWKAVFGKPADALEKS-MEDEYMIIDNDPPITRNISVPRDMSTLSCSSFTAGIVEAVLDGLGFPAR-VTAHNTPPRRTTILIKLEVLDREEVL Rhior3 -----------------------MLQYAQKRV-NGIQDLERKLNEFGYRVGFRMLELLTWRSKRETKVLGILYFIHSTVWKALFGKQADSLEKS-TEDEYMISDNEPILTKYISVPKELSQLNCNAFVAGIVEAVLDGCQFPAR-VTAHTVPPQRTTILIKLDVLEREELL Rhoto1 IYDRPLVKSREVSLGAWAYLFAELVQYTQKRV-SGISEFEKRLSIIGYRVGARLLELLPLRPSRTLRLLPILTYVHSTLYRYLFGRPADSLERS-TDDEYMIGDDDMVITRGVEVPKEMKDLSCGALVAGIVEAVMDGAGFPAR-VTAHSVPPRRTVILIKLDVLAREAAL Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 IYSESLLFKREASLSAMAFLFQEMISQLHRTC-KTAGDFETKLSDYGHNIGIRLLELLNFRRRRDLKILDILQFIHGTLWSYLFNHVSDDLVKS-SENEYMIVDNFPTLTQFIP----GENVSCEYFVCGIIKGFLFNAGFPCG-VTAHRMPSQRTVYLIQFDVLDREGLR Salro PLDRALPRVPDISLSTYALLFSEVVRYTTNRV-NSVPELEQKLAVIGRRVGVRLVEVMAMRSRRRIKIHDVLAFLQTNLWRTLFGKPADLLEQV-TSCSYMLSDHDMLVNKFISISKEYGDLNCAAFVGGIVEAAVDGMGFPAE-VAAHTVE-KGTTLLIKFDKIPQEAL- Schco3 IYDRNLNKTREVSLSAFAFLFSELVQYTQKRV-SGINDLERRLNTLGYRVGTRVLELMSWRPKREIRFLPALMSIHTNVWRTVFGKPADAIEKS-VEDEYMIIDNDPPIERSISVPRDMSQLSCSSFTAGIVEAVLDGLGFPAR-VTSHNTPPNRTTILIKLEVLEREELL Schpo1 VYEQNLNKIRDVNLSSFAFIFSELIQRIQSQV-SGIQEFEEKLNEHGYRVGQKLVELVVWRPKRETRILGILQYIHSSVWKYLFGKHADSLEKS-KEDEYMIVDNNPLLNKFISVPKEMNQLNCCAYLAGIIEGFLDSAQFPCK-ASAHSVPPYRTVILIKLDVIAREEVL Sorma IYHRPLNRTKELSKAAFAYLFAEMVSYAQRRV-TGIQELEKRLNLQGHPIGLKLLDLLLFR--RPLNIIALLHFIKINIWTHLFGRQADRLEKS-SNDEFMIIDNEPLVNAYISVPKEMSQLNCAAFAAGIIEGVCDGAGFPAR-VTAHTVGPGRTVFLVKFQVLEREALI Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ILERNLSKGREVSVAAYAFLFAEMLSYATKKS-SGIQDMEKKLSDFGYRVGIRFLELIVFRGRRDTRLLNVLSFIHSTIWKTLFGKVADALEKG-TEDEYMISDNEPNITKFIAVPREMSQLSCGAFIGGVVEAVLDGCGFPAR-VSAHSTAPLRTTILMKFDVLQRDKTF Sporo1 IYERNLIKSREVSLGAWNFLFGEIVQYTQKQV-SGISEFEKRLSILGYRVGTRLLELLPMRPSRTLRLLPILTYVHSQLYRYLFNRPADSLERS-TEDEYMIGDDDMVVTKGIVVPKEMKELSCAALVAGIIEAVLDGSGFPAR-VTAHSVPPRRTILLIKLDVLEREQAL Stehi1 IYDRPLNKSRQVSASSFAFLFSELVQYTQKRV-NGINDLERRLNTLGYRLGTRVLELMVWRPKREIRFLPALMNIHTNVWKAVFGKPADAIEKS-VEDEYMIIDNDPIITRNISVPRDMSQLSCSSFTAGIVEAVLDGLGFPAR-VTAHNTPPSRTTILIKLEVLEREELF Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------MVGLSSFSYLFSELIRHSQSRV-TAIGPLEAKLDAAGFQVGARMVDLISLRGKREVKLKNVLVLIQTSVFRTLFGKSADALAQYSSDEEYHIVDNEPLVNRYISVPRDMSDLNCGAFVAGIVKGVLAGAGFPAE-VVAHNTPPYCTTYQVRVTVRAREK-- Treme1 ILDRPLNKTREVSNSAWAFLFAEIISYSQSRV-DSVTDLERRLASLGYEAGQRILSLLLLRPKREHRLIPILQFVHTQVYKYVFGKPADGLERS-VEDEYMLTCNSPPLTQHISIPRDMGQLSCEAFTAGLVEGVLDGLDVPAR-VTAHTVPPQRSVILIKLDVMDREEIL Trire2 IYHRPINRTKELSQASFAFLFSEMVAYAQKRV-KGIQELEHKLNVQGHSIGIKLLDLLLYR--RPQNIVALLHFIKQNVWLHLFGRQADRLEKS-TDDEYMIIDNEPLVNQYISVPREMSQLNCAAFVAGVVEGVCDGADFPAR-VTAHTVGPGKTVFLVKFRVVEREAFL Umbra1 LLERNLNRTKEVSLSALSFLFSEMIQYAQKRV-NGIQDLERKLNELGYRVGLRMLELLVWRPKRETRVLSILYFIHTALWKGLFGKQADSLEKS-TEDEFMISDNEPILTKYISVPRELSQLNCNAFIAGVVEAILDSAQFPAR-VTAHTVPPLRTTILIKFDVLEREEML Ustma22 IVERPRDKTREVGMSSLSFLFGEIVSYTQNRV-TGVSELEKRLSLIGYTIGQRVLAITLHRPKRETRLLPVLLWIHTAFWKAAFGKPADSLERS-TEDEYMISTNVPCFSRTICVPNDMSQLSVEAITAGMVEAALDGLGFPAR-VTAHTVPPNRTTILIKLDVMDREDAL Walse1 -MELQVDQLKQVALGSWAFLFSEIINYNLKRV-DGIAELESKLNWLGYRVGQRELELYKFRPRQHTSLIEVLQFIHTHIWRSLFGKTADSLEKS-KENEYMISDNTPILSRSISIPKDLKNLSTESFTSGIVESVLDGLNFKSK-VTAHSVPPQRTTILIKLI-------- Zygro1 IYSDSLMHRKEVSLSAMAFLFQEMIATIHRAS-SSAQDFETRLNGYGYGIGTRLVELLNLRRPRDLKILDILQFVHGTMWTYLFGHASDDLVKS-SENEYMIVDNLPMLTQFIP----AGR-SCDYFTCGIIQGFLDSAEFPCR-VSAHSMPDQRTVYLIQFDVLERDNLR [Cluster2261.fasta_al_trimmed; alignment length = 132] Allma1 FIGLSYTAVPLYRLFCTGVGGTVRKLKITFNADTARALDWTFRPQQRVVEVVPGETALAFYTAKNRSDQDVIGISTYNVMPGPYFNKIQCFCFEEQKLRAGEEVDMPVFFFIDPAFLDDPNTITLSYTFFNA Ashgo11 FLGLAYAAVPLYRLLCTGFGGTPKRIRVSFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNTSDKDIIGMATYSITPAQYFNKIQCFCFEEQKLLAGEEVDMPVFFFIDPDFATDPQMLVLHYTFFRA Aspfu1 TLALAYGSVPLYKMVCIGWNGQPRRLRITFNGSVSDVLPWKFTPQQREVCVLPGETALAFYTATNKGPTDIIGVATYSVTPAPYFSKIQCFCFEEQKLNAGESVDMPVFFFIDPDFVKDPAMITLSYTFFKA Aurde31 IVGVTYAAVPLYRAFCTGFAGTPRRIKVNFNADTSDALPWGFFPQQKYVYVVPGQTALAFYTARNRSANDIIGIATYSVMPAPYFAKVECFCFEEQKLLAGEEVDLPLFFFIDKDFLDDPLMIVLSYTFFRA Batde5 FIGLTYAAVPLYKMLCTGVDGTPQPIRIIFDSSIADTMPWKFVPETRQIRVVPGETALAFFRASNPGTEDMVGISTYSVTPAQYFNKIQCFCFEEQKLVAGEEIDMPVFFYIDPEFAYDPWMITLHYTFFKS Botbo1 AVGVTYAAVPMYRAFCTGYSGTPKRIKVHFNADTSGVLPWSFTPQQKFVLVKPGESALAFYTAKNRSEEDIIGIATYNVTPAPYFAKVECFCFEEQKLRAGEEVDMPLLFFIDKDFAEDPSTVVLSYTFFKA Botci1 TVAFSYGSVPMYKMICTGWGGQPKRIRVTFNGSVSDVLPWKFTPQQREVRVLPGETALAFYTATNKSDEDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYIDPDFVNDPNMVTLSYTFFKA Caeel AIGCTFAAIPAYRIFCTSFGGLTRLIRVQFNSDVPSSMRWEFKPQQHEIYVHPGETALAFYTARNPTDKPIIGISSYNLTPAYYFNKIQCFCFEEQILNPGEQVDLPVFFYIDPDYVNDPALILLSYTFFEA Canalb1 FLALAFSAVPIYRAICTGWGGIPKRIRIQFTCQSSGILPWKFTPLQREVYVVPGETALAFYRAKNMSKEDIIGMATYSISPAGYFNKIQCFCFEEQRLSAGEEVDMPVFFFIDPDFAKDPAMVVLHYSFFKA Cangl FLGLAYAAVPLYRAICTGFGGVPKRIRVSFTSEVSQILPWKFTPQQREVYVLPGETALAFYKAKNNSDKDIIGMATYSITPAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPSMLILHYTFFRA Capow TAGLAYAAVPLYRMFCTGYGGYVRIIKIQFNADTAASMQWKFHPVQREIQVIPGEPALAFYSATNPTDKPIVGISTYNVLPGVYFNKIQCFCFEEQRLGPHEQVDMPVFFFIDPEFDKDPAMITLSYTFFAS Catan2 FVGLSYTAVPLYRLFCTGIGGTVRKLRIRFNSDTARALNWQFRPQQAFVDVVPGETALAFYTAKNKADADIIGISTYNVFPAPYFNKIQCFCFEEQKLRAGEEVDMPIFFFIDPGFLEDPNCITLSYTFFNA Cioin ------------------------------------------------------------------------------------------------------------------------------------ CocheC53 FVALSYGSVPMYKMICTGWGGQPPRIRITFNGSVSDVLPWKFVPQQREVRVLPGETALAFYTATNKSPEDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYIDPEFVTDPNMVTLSYTFFKA Coere1 FLGLSYAAVPLYRLLCTGFMGTPRKLKIRFSGQVSTVLNWSLKPEQRQITVVPGETALAFFKAYNLSDKPIVGIATYNVIPAQYFNKIQCFCFDEQQLDPKEEVDMPVFFFIDPEFALDPLMITLSYTFFKA Conco1 VLGLTYASVPLYRMFCTGYNGTPRKIRVTFNSSISDSLQWSFTPQQKHIRVVPGESALAFYTAKNLADEDIIGISSYNVIPGQYFNKIQCFCFEEQKLAPGEEVDMPIFFFIDPEFAEDPSMVTLSYTFFKA Conpu1 ALGMTYAAVPLYRMFCTGFAGTPRRITVHFNADRSEALPWKFSPQQKFVNVLPGETSLAFYRARNNSRQDIIGIATYNVTPAPYFSKVECFCFEEQKLLAGEEVDMPLLFFIDKDFVDDPACVVLSYTFFRA Copci AVGASYAAVPLYRMFCTGFAGTPRRIKVHFNADKSEQLPWKFTPQQKFVNVLPGESSLAFYTAKNDSEQDIIGIATYNVTPAPYFSKVECFCFEEQKLLAGEEIDMPLLFFIDKDILEDPACVVLSYTFFRA Croqu1 ALGISYAAVPLYRAFCTGYNGTPKVITVRFNADKADTLNWKFWPCQKSVKVKPGETVLAFFKAKNLSDTDILGVATYNVTPAPYFAKVECFCFDEQRLLAGEEVDLPIFFFIDKDFMDDPLMIVLSYTFFKA CryneH991 ALGITYAAVPLYRAFCTGFAGTPKRITVHFQSSSAESLPWKFEPVTKSVRVLPGETALAFYTAKNYGDKDLIGIATYNITPAPYFAKVECFCFEEQKIRAGEEVDLPVFFFIDRDIVDEPQLVVLNYTFFRA Crypa2 TVAFSYGSVPLYKMICTGWGGQPKRIRVTFNASVSDVLPWKFTPQQREVRVLPGETALAFYTATNTSDQDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDYLTD------------- Debha1 FLAAGFAAVPLYRAICTGYGGTPKRIRIQFTCQASGILPWKFTPQQREVYVVPGETALAFYKAKNMSKEDIIGMATYSVTPAPYFNKIQCFCFEEQRLSAGEEVDMPVFFFIDPDFAKDPQMVVLNYSFFRA Dekbr2 FLSISFASVPVYRAICTGWNGTPRRIRIQFTAETSRQLPWKFVPQQREVYVAPGETALAFYKAKNKTDHDITGMATYSVAPAPYFNKIQCFCFEEQRLGAHEEVDMPLFFFIDPEFATDPAMVVLHYTFFKA Dicdi ILGLSYAAVPLYRIFCTGYGGTT---KVTFSASTANKIPWTFKPTQSTIECLPGEPVLCFYRATNNTDTPIIGVATYNITPGTYFTKIQCFCFDEQRINAHETIDMPVLFVIEPELLDDKNMITLSYTFFKS Dmel IVGLSYAAVPLYSIFCYSYGGTTRVLKIRFNADIGSSMRWNFKPQQYEIKVAPGETALAFYTARNPTDKPVIGISTYNVIPGAYFNKIQCFCFEEQQLNPHEEVDMPVFFYIDPEITADPALITLSYTFFEA Enthi ------------------------------------------------------------------------------------------------------------------------------------ Falba VCGLSYAAVPLYRMFCTGFGGTPRVVKIHFTSDASDNLRWRFKPVQGTLHLRVGETALAFYEAENQSGRDAVGIATYNVTPAEYFNKIQCFCFEYQQLRAGERVDMPVFFYIDPEFANDPRMIILSYSFFES Fomme1 VPSMSYAAVPLYRTLCTGFSGTP---------------------KREEFGALPVETSLTFYKARNMSSQDVIGIATYNVSPATCFTKFECFCFEEQKLFAGKEVNVLLPSFIGQDVLNDPACVVLSYTFFRA Fusgr1 FIALTYGSVPLYKMICTGWGGQPKRIKVTFSASVSDVLPWKFVPQQREVRVLPGETALAFYKATNKSDQDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDLLNDMNMVTLSYTFFKA Galma1 AVGASYAAVPLYRMFCTGFAGTPGRIKVHFNADKSEQLPWTFTPQQKFVSVLPGETSLAFYRAKNTSKKDIIGIATYNVTPAPYFSKVECFCFEEQRLLAGEEVDMPLLFFIDKDILDDPACVVLSYTFFRA Ganpr1 MSGLSYAAVPLYKLVCTSIDGTPKKLRIHFNADVSQTLGWKFRPQTREVRVVPGETALAFYTATNNSDEDIIGISTYSVVPAQYFNKIQCFCFEEQKLLAHESVDMPVFFYIDPAFADDPWMITLSYCFFKS Gloin1 GIGFTYASVPLYRMFCTGFSGTPRRIRVHFNADTSLALDWSFIPQQREVYVLPGETALAFYTAKNKSDQDIIGLATYNVTPGQYFNKIQCFCFEEQKLQAGEAVDMPVFFFIDPEFPEDPSMITLSYTFFKA Hisca1 TVALAYGSVPMYKMICTGWNGQPRRLRITFNGSVSDVLPWKFTPQQREVRVLPGETALAFYTATNKGPEDIIGVATYSVTPSPYFSKIQCFCFEEQRLSAGESVDMPVFFFIDPDFVNDPAMITLSYTFFKA Klula1 FLGLAYAAVPLYRAICTGYGGIPKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNNSDKDIIGMATYSITPSPYFNKIQCFCFEEQKLAAGEEVDMPVFFFIDPDFASDPSMIILHYTFFKA Lacbi2 AVGASYAAVPLYRMFCTGFAGTPRRIKVHFNADKSEQLPWTFTPQQKFVSVLPGETSLAFYKAKNTSDRDIIGIATYNVTPAPYFSKVECFCFEEQRLLAGEEVDMPLLFFLDKDMLDDPACVVLSYTFFKA Lenti61 GIGVTYAAVPLYRMFCTGFAGTPKRIKVHFNADTSDALPWTFTPQQKFVSVLPGETSLAFYKAKNNSDKDIIGIATYNVTPAPYFAKVECFCFEEQKLLAGEEVDMPLLFFIDRDVLDDPQCIVLSYTFFRA Malgl1 ALGLTYAAVPLYRAFCTGYSGTPERIRVSFNASTSNQIPWSFVPEQREIFVLPGETALTFFKAHNKSDQDIIGIATYNVIPAPYFNKIECFCFEEQKIRAGEEIDLPVFFFLDKEMLEDKESIILAYTFFSA Mellp23 TLGLSYAAVPLYRVFCTGYNGTPKSITVRFNADKSDTLNWKFWPCQKSVKVKPGETVLAFYKAKNLSDKDILGVATYNVTPAPYFAKVECFCFDEQRLMAGEEVDLPIFFFIDKDFMEDPLMIILSYTFFKA Mnele MFGVSAASVPLYKVFCTGYGGTTRPITVSFTATVNPGLDWEFIPVQNSVSLVPGETCLAFFTAKNNSSRVITGISTYNVTPGAYFNKIQCFCFDEQTLNPGEELDMPVFFYIDPEYVYDPELVQLHYTFFDT Monbr -----------------------REIRIRFNADTSATMQWSFKPQQREVTVVPGETALAFFTAKNPTNQPIIGISTYNVVPGVYFNKIQCFCFEEQRLNPGEEVDMPVFFYIDPEFAEDPSMITLSYTFFQA Morel2 TLGLSYAAVPLYRMFCTGLGGAPRRIKVKFNADTSTSLQWSFLPQQRQVSVLPGETALAFYTAKNKSKDDVIGIATYNVAPAPHFNKIQCFCFEEQKLTAGESVDMPIFFFIDPEFANDPDMVTLSYTFFKA Mucci2 MLGMSYAAVPLYRLFCTGYSGTPRRIRITFESNTSDSLPWTFKPEVREVFVVPGETALTFYKAKSKAKEDVIGIATYNVTPGSYFNKIQCFCFEEQKLTPGEDVDMPVFFFIDPDFLDDPLMITLSYTFFNS Mydma TAGLSYAAVPLYRIYCSGYGGSVRKLIIRFEASTGNQLQWSFKPQQKEVQLTPGETALAFYTAKNLSDRPIIGIATYNVVPGQYFNKIQCFCFEEQQLNPREEVDMPVFFYIDPEIDEDPLMIILSYTFFES Neucr2 TVALSYGSVPMYKMICTGWGGQPKRMRVTFSASVSDVLPWKFVPQQREVRILPGETALAFYTATNMSDKDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDYLNDLNMVTLSYTFFKA Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------ Phybl2 MLGASYAAVPLYRLFCTGFSGTPKRIRITFESNMSDTLAWSFKPELREVYVVPGETALTFYRAKSYAKEDVVGIATYNVTPGSYFNKIQCFCFEEQKLSPGEDVDMPVFFFIDPDFLEDPYMITLGYTFFDA Picst3 FLSLAFAAVPIYRAICTGWGGIPKRIRIQFTCQSSGILPWKFTPLQREVYVVPGETALAFYRAKNMSKEDIIGMATYSVTPAPYFNKIQCFCFEEQRLSAGEEVDMPVFFFIDPEFAKDPAMVVLHYSFFKA Plicr1 ALGVTYAAVPLYRIFCTGFAGTPKRIRVHFNADSADALPWLFTPQQKFVDVLPGETSLAFYRAKNLSKDDIIGIATYNVTPAPHFSKVECFCFEEQKLLAGEEVDMPLLFFIDKDVLDDPACIVLSYTFFRA Polpo VLGASYAAVPLYRVFCTGYGGTV---KVTFTSSVGNKIPWTFKPTQQSIEVLPGEPVLAFYRATNNTDAPIIGVATYNITPGPYFTKIQCFCFDEQRIKSNETIDMPVLFVIEPDLLDDKSLITLSYTFFKS Pucgr2 TLGLSYAAVPLYRAFCTGYNGTPKTITVRFNADKSDTLDWKFWPCQKSLTVKPGETVLAFYKAKNLSDHDLLGVATYNVTPAPYFAKVECFCFDEQRLLAGEEVDLPIFFFIDKDFVEDPLMIVLSYTFFKA Punst1 AVGVTYAAVPLYRAFCTGFAGTPKRIRVRFNADASEQLPWSFKPQQKYVSVLPGETCLAFYTAKNKSDQDIIGIATYNVTPAPYFAKVECFCFEEQKLLAGEEVDMPLLFFIDKDVLDDPACVVLSYTFFRA Rhior3 MIGISYAAVPLYRLFCTGFNGTPRRIRITFESNTSDTLPWSFKPELREIYVVPGETALTFYKAKSKAKTDIIGIATYNVTPGSYFNKIQCFCFEEQKLSPGEDVDMPVFFFIDPDFLDDPLMITLSYTFFNS Rhoto1 VTAGSYLAVPLYRVFCTGYGGTPRRIRVTFNADASDALPWSFEPQQKEVRVLPGETALAFYTATNHSSEDIIGIATYNVTPAPYFAKVECFCFEEQRLLAGEEVDLPVFFFIDRDFVDDPLMVTLSYTFFRA Rozal11 ---MAWSIIPLFEAFCTGLFGLSRPYQVNFTALTDHTLPWTFKSKQKFLTVYPGQTALTFFEAHNPTDKEMSGIAIYTV------------------LKPGERVDMPVFFYLDPELLYDDEAINLSYTFGRT Sacce1 FLGLAYAAVPLYRAICTGFGGIPKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNYSDKDIIGMATYSIAPAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPAMIILHYTFFRA Salro ILGFSYAAVPLYRAFCTGYGGTVRQITVRFNADTSATMPWSFKPQQKAVTVVPGETALAFFTASNPTDEAITGISTYNVVPGQYFNKIQCFCFEEQRLNPNEEVDMPVFFYIDPEFAEDPNLITLSYTFFKS Schco3 AVGVTYAAVPLYRMFCTGFAGTPHRIRVHFNADHSEQLPWKFIPQQKFVNVLPGETSLAFYKAKNVSNEDIIGIATYNVTPAPYFSKVECFCFEEQRLLAGEEVDMPILFFIDKDMLEDPSCVVLSYTFFRA Schpo1 ------------------------------------------------------------------------------------------------------------------------------------ Sorma TVAFSYGSVPMYKMICTGWGGQPKRMRVTFNASVSDVLPWKFVPQQREVRVLPGETALAFYTATNKSDKDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDYLNDLNMVTLSYTFFKA Sphar FLAASYAAVPLYRAFCTGYGGTIRPIRIRFNADTSNNMQWAFKPQQKEVTVIPGESVLAFYTATNPTDKPISGISTYNVIPGQYFNKIQCFCFEEQRLNPDEQVDMPVFFYIDPEFADDPFMITLSYTFFES Spipu1 FIGASYAAVPLYKLICTGLDGTPRKVKIRFASSVSDSMRWSFVPVTQEISVVPGETALAFYTAHNPTDEDIVGISTYSVVPAQYFNKIQCFCFEEQRLEANEEVDMPVFFYIDPEFAYDPWMITLHYTFFKS Sporo1 VTASSYLAVPLYRVFCTGYAGTPKRIKVQFNADSSDSLPWTFTPQQKEVRVLPGETALAFYTAKNLSDEDIIGIATYNVTPAPYFAKVECFCFEEQRILAGEEVDLPVFFFIDRDFVDDPLMVTLSYTFL-- Stehi1 AVGVTYAAVPLYRMFCTGFAGTPKRIKVHFNANRSEQLPWKFTPQQKYVSVLPGETSLAFYKARNESKEDVIGIATYNVTPAPYFAKVECFCFEEQKLLAGEEVDMPLLFFIDKDVLDDPACVVLSYTFFRA Tapde11 TLGLSYAAVPMYKAYCTGFGGTPRPIRITFNSQVSDSLQWKFTPQQRQVTVVPGETALAFYTATNLSNEDIIGIATYNVTPAPYFSKVQCFCFDEQKLNAGETVDMPVFFFIDPTVCDDPRMITLSYTFFRA Thetr TFGLSYAAVPLYRMFCTGYGGTTRKLRIQFAAETAAGMPWKFVPTQREIRIVPGQTVLACFTATNNTDEPMIGIATYNVTPGKYFHKVQCFCFEEQRLNPREEVDMPVFFYVDPSIVDDPRMITLSYTFFKS Treme1 AIGLTYAAVPLYRAFCTGYSGTPKRITVRFEATSSDALPWKFEPQQRSVRVLPGETALAFYKARNDSDRDLIGIATYNMTPAPYFAKVECFCFEEQKIRSGEEVDLPVFFFIDKDIMDDPSLVVLSYTFFKA Trire2 TLALSYGSVPFYKMICTGWGGQPNRIKVTFNAAVSDILPWKFVPQQREVRVLPGETALAFYKATNMGDQDIIGVATYSVTPAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDLLNDINMVTLNYTFFKA Umbra1 MLGVSYAAVPLYRIFCTGYSGTPRRIRITFESNTSDALQWSFKPELREVRVVPGETALTFYRAKNNAKEDIVGIATYNVTPGQYFNKIQCFCFEEQMLRAGEEVDMPVFFFIDPDFNEDPYMITLSYTLFNA Ustma22 TLGFSYAAVPLYRAFCTGFSGTPKRIRVTFNADASDAIPWSFTPVQKEIYVLPGETALAFYTAKNKSDKDIIGIATYNVSPAPYFAKVECFCFEEQKLLAGEEVDLPVFFFIDSDVLDDPSTVVLSYTFFSA Walse1 VLGASYAAVPMYRAFCTGFAGTPKRITVKFAAEASDMLPWKFTPQQKEIKVLPGESALAFYTATNKSDEDIIGIATYNVTPAPYFAKVECFCFEEQRLLAGETVDLPILFFIDKDFLDDPSMVVLNYVFFKA Zygro1 FLGLAYAAVPLYRAICTGFGGIPKRIRIGFTSEVSQILPWKFTPEQREVYVQPGETALAFYRAKNTSDKDIIGMATYSITPAQYFNKIQCFCFEEQRLAAGEEVDMPVFFFIDPDFASDPNMMMLHYTFFKA [Cluster2262.fasta_al_trimmed; alignment length = 233] Allma1 MVESVRAAIIGQGSSGSYFCRV-GVFKPKDEEPYGDLNPKWTKWLHRCLIPNV----------------------------------------------------------FVNQFQR--LTILDYLMRNTDRGLDNWMIKVAAIDHGLAFPFKHPDWRSY------------------------------------------------------------------------ Ashgo11 VVSECVEAIIASGSSGSYFAYL-GVFKPKDEEPYGPLSPKWTKWLHRCLIPNLGYLCEAAASLLDRRLRTNLVPWTDTVVLESMNFY-AQRKIGSFQLFLDGYVGADVFLQLRVQLEK--LIILDYIMRNTDRGLDNWMIKLAAIDNGLSFPWKHPDWRSYPYGWLYLPLDIINQPFTRETREHFLPIL-RSVGWWETSFHGLFMWKKQWAVLKGQAFNVLETLKGPLELVRR Aspfu1 VVESVRTAIISQGSSGSYFARV-GVFKPKDEEPYASRNPKWTKWLHRCLIPNLSYVSEAAAYVLDSRLRTNLVPYTDIVYLSSKSFYYLPPKAGSFQVFLKGYKDANLFLRFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPD------------------PFSQKTRDHFLPLL-TSTAWWSGTLRRVFMFARQIAVMKGQAWNVVETLKGPLELTRR Aurde31 MADAVRAAIIAKGSSGSYFARV-GVFKPKDEEPYGNANPKLTKWIHRCLIPNLSYISEAAASLLDERLGLNIVPRTELVSFASPAFYYLPEKIGSMQCFMHGFQDASGFLRFREELEK--LVILDYLMLNTDRGADNYMLKLAAIDNSLSFPHEHPKWRSFTYGWLYLPVNVIGRPFSEKTRRQILPLL-TSKEWWEETLRKMFMFARQLAVLKGQAWNIVQSLRGPLELTRR Batde5 ILCDVQLAIISQGSSGSYFCRV-GVFKPKNEEPYGNMNPKWTKWLHRCIVPNQGYVSEAAASYLDRRLGLNLVPRTEIVCLASPTFHYLPTKTGSFQLFLTGYKDATTFFRFQLSFER--LVILDYLIRNTDRSSDNWMPSIAAIDNGLAFPTHHPDMRSYPYSWAFLPIAHK--PFSPDTAHLVLPLI-TSSQWWETTLETLFLWRKQRSVIRGQGYNLTGVLGSPYHLVRL Botbo1 IVNSVKTAIIAKGSSGSYYARV-GVFKPKDEEPYGRLNPKTTKWIHRCLIPNLSYISEAAASLLDNRLNLYIVPHTELVSLSSPAFFYLPDKIGSMQCFQHGYQDASVFLRFREELEK--LIILDILMRNTDRGLDNFMIKIAAIDNSLSFPHQHPKWRSYTYGWLFLPVSLIGRPFSENTRKHFLPLL-SDPEWWAETLRKLMMFARQMAVMKGQGWNIVQSLKGPLELTRR Botci1 ---------ISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYTLDCRLRTHLVPYTDIVHLSSKSFHYLPPKVGSFQVFLKGFKDANIFLRFREELEK--LVILDYIMRNTDRGLDNWMIKVSSSDN---------------------------------------------------------MFARQIAVMKGQAWNVVETLKGPLELTRR Caeel KFNEACRAIIAQGSSGSYFVKI-AVFKPKNEEPYGSLNPKWLKWIHRCLPPNQGYLSEVGASLVDEKLKLGIVPPTGVVELAAPTFYYLPEKTGSFQLFVKGYQDAAHWLRFQFLFEK--LVALDYIIRNTDRGSDNWLIKVAAIDNGLAFPFKHPDWRAYPFGWALLPQAQI--PFSDDIVDLLLPKL-DDTNWVRELLRRVFIFEKQMSVMRGQIFNLREALMSPYQLIQM Canalb1 LLFKITKIIISTGSSGSYFIFI-GIFKPKDEEPYGPLSPKWTKWAHRCLIPNLGYISETAACVLDRQLQSYIVPHTEIVELRSPTFFYLPKKKGSFQLFLKGYINADIWLKFQEELEK--LVILDYLMRNTDRGLDNWMIKIGAIDSGLAFPWKHPDWRSFPFGWLFLPLSIIGQPFSRRTRNHYLPLL-TSKKWWEETLKDVFMWLKQLAVLKGQAFNIVEILKGPLELTRR Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow LLSEVEDAFIAQGSSGSYFVRI-GVFKPKNEEPYGKLNPKWTKWFHKCLIPNQGYMSEAGASLIDRKLGLNVVPPTRVVMLASPSFYYLPPKVGSFQLFVNGYKDAIVYLTFQHQFER--LVILDYLIRNTDRGNDNWLIRIAAIDNGLAFPIKHPDWRAYPYHWAWLPYAKV--PFSDESRDAFLPLL-MDETYMDDLLHTLFNFNKQISVFRGQLQNLVAALKTPLDLIQM Catan2 IVDSIRDAIIGQGSSGSYFCRL-GVFKPKDEEPYGELNPKWTKWIHRCLIPNVGYMSEAGASLLDQRLGFGIVPLTKVVSLASPAFYYLPMKSGSLQLFLRGFKDASMFLKFLDQFQR--LTILDYLMRNTDRGLDNWMIKVAAIDHGLAFPFKHPDWRSYPYGWLYMSISKL--PYLPHLRTYMTT-----------------------------------C---------- Cioin LVRNAETAIIAQGSSGSYFVKI-GVFKPKNEEPYGQLNPKWTKWMHKCLIPNQGYLSEAGASIIDSKLGLSIVPKTKVVHLASETFNYLPPKVGSMQTYVEGYKDAEFWLRYQLQFER--LVVLDYIIRNTDRGNDNWLIRIAAIDNGLAFPYKHPDWRAYPYHWTWLPEARI--PFSQETKDLVLDKL-SDMHFVESLLHELFLFDRQMAVMRGQILNLCKGMNTPEEIVNM CocheC53 IVESVRTAIITQGSSGSYFARV-GVFKPKDEEPYASRNPKWTKWIHRCLIPNLSYISEAAAYVLDTQLRTNLVPYTDVVGLSSKSFHYFPEKLGSFQVFLKGFKDANIFLKFREQLEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPDWRSYPFGWLFLPVSLIGQPFSEATRRHFLPLL-TSKHWWSDTLRKCFMYAKQIAVMKGQAWNVVETLKGPLELTRR Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 LVQLVREAIIAQGSSGSYFCTV-GVFKPKNEEPYGHLNPKWMKWLHRCLIPNLGYISEAGASLIDRRLQMGLVPRTEVIRLSSTSFHYLPLKIGSFQLFLHKYQNASTFLEFRLQLEK--LVIFDYLIRNTDRGLDNWMIQIAAIDHGLAFPHKHPDWRSYPYGWLSLPQSLINRPFSPSIRAYFLPLL-SSARWWQQTMRKLFMFQAQMAVLKGQGWNIVESLKGPIELCNR Conpu1 TAQSVRSAIIAKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWLHRCLIPNLSYISEAAASLLDERLALNIVPRTALVTLSSQAFFYLPGKIGSMQYFLHGFTDASDFLRFREELEK--LVVLDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPQWRSYAYGWLYLPVSLIGPPFSEKTRNHFLPLL-TSKTWWEETLQKLFMFRRQMAVIKGQAYNIIESLK-PLELTRR Copci IVKSVKTAIISKGSSGSYFARV-AVFKPKDEEPYGRLNPK--------------------------------------------AFFYLPEKIGSMQYFLHGYQDASEFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPQWRSYTYGWLYLPVSIIGRPFSEKTRNHFLPLL-TSKAWWEETLEKLFMFARQLAVIKGQAWNIVQSLKGPLELTRR Croqu1 TVEAVRLAINLSGSSGSYFCKV-GIFKPKDEEPYGAMNPKWTKWFHRCLIPNLSYLSEAAASVLDRRLEAYIVPHTEVVNISSSTFFYLPQKPGSFQLFCNGFEDASTVLRFRHEMEK--LVILDYLMRNTDRGLDNFMIKVAAIDNSLAFPHHHPNWRDYSYGWLWLPISLIGQPFSSGTRAHYLRLL-TDPSWWAETLRKLFMFERQIALLKGQGWNIVESLRGPLELCRR CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 IVEGVRVAIISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYTLDCQLRTHMVPYTDVVWLSSKSFHYLPEKPGSFQVFLKGFKDANIFLRFREQLEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPDWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLL-TSTAWWSQTLRKIFMFSRQIAVMKGQAWNVVETLKGPLELTRR Debha1 LVVGITDLIISQGSSGSYFIYA-GIFKPKDEEPYGPLSPKWTKWLHRCLIPNLGYVSEAAASILDQQLLSFIVPHTEIVYLKSSSFYYLSPKIGSFQCFLKGYMEAQAWFHFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDSGLAFPWKHPDWRSFPFGWLFLPLSIIGHPFSMNTRNLYLPLL-TSIMWWETTLKDVFMWKKQLSVLKGQAFNVVEVLKGPLELTRR Dekbr2 IVLEAIYAMIDTGSSGSYFIYI-GVFKPRDEEPYGSLSPKMTKWVHRCLIPNIGYIAESATSLLDRLLELNLVPYTDIVEFQSESFFSCPRKIGSFQLFLQGFVGADTFFKIKVQVEK--LIILDFIIRNTDRGLDNWMLKAKAIDNGLSFPWKHPNWRSFPYGWLYLPLQFLGMPFSEETRNHFLQFL-TSVTWWKNALHEIFLFEKQMQVLKGQAWNVVQTLKGPLDLVRK Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VVSEIRYAIIVQGSSGSYFCRI-AVFKPRDEEPYGAQNPKWAKWLQRCLIPNVGYISEAAASAVDRHLGLGIVPRTRVVRLASPTFHYLPRKIGSLQVFMPGFADAQFVLGFQLLFER--LVILDYLIRNTDRGNDNWLIRIAAIDNGLAFPWTHPEWRTYPFGWTSTPHAHV--PFSEPTRLQFVPLL-ADETFMNQLLRAISAFAGQMAVLRGQAANLVKALLTPLELTQM Fomme1 IVMSVQKAIISKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWLHRCLIPNLSYISEAAASLLDDRLNLNIVPKTQLVSFSSPAFFYLPDKIGSMQCFMHGYQDSSDFLRFREELEK--LVILDYIMHNTDRGADNYMIKIAAIDNSLAFPHEHPRWRSYTYGWLYLPVSLIGQPFSQKTRDHFLPML-TSKSWWEETLRKVFMFQRQLAVVKGQAYNVVQSLKGPLELTRR Fusgr1 IVESVRSAIISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYVLDCQLRTHLVPYTDVVWLASKSFHYLPAKPGSFQVFLKGFKDANVFLRLREELEK--LVILDYIMRNTDRGLDNWMIKVGAIDNSLSWPWKHPDWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLL-TSTSWWTQTLKRVFMFAKQVAVMKGQAWNVVETLKGPLELTRR Galma1 VVRSVKDAIITKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWLHRCLIPNLSYISEAAASLLDDRLALHIVPPTQLVSLSSRAFFYLPEKIGSMQYFLHGFQDASDFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPQWRSYTYGWLYLPVSVIGRPFSEKTRSHFLPLL-TSKAWWEETLEKLFMFARQLAVIKGQAWNIVQSLKGPLELTRR Ganpr1 TIQSSVRAIIVKGSSGSYFVKV-GVYKPRDEEPYGAMNPKWTKWLHRCLIPNLGYVSEAAASFVDRKMGLNIVPRTEIVSLSSPAFHYLPLKTGSFQLFVRGFKDSGTFFRFQLQFER--LVVLDYLIRNTDRGMDNWLVRIAAIDNGLAFPHKHPDWRSYPYGWAFLPIARV--PFSQNTRELVLPLL-TNEAWWSDLLEQLFMWRRQKAVMRGQGYNLVEILRSPWALVRR Gloin1 IVDSVNSAIIRQGSSGSYFCRV-GVFKPKNEEPYGQLNPKWTKWIHRCLIPNLGYISESAASLLDKRLLLNIVPVTEVTRISSPSFHYLPNKEGSFQVFLDGFIDANIFLRFREQFEK--LVILDYLMRNTDRGSDNWMIKVAAIDNGLAFPFKHPDWRSYPYGWLYLADSLIKQPFTQNTRNRFLSML-SDPKWWKETLRNLFMFEKQIAVLKGQGFNIVETLKGPYELCAK Hisca1 VVDSVRTAIISQGSSGSYFARV-GVFKPKDEEPYASRNPKWTKWIHRCLIPNLSYVSEAAAYVLDTRLKTNLVPYTDIVYLSSKSFYYLPAKVGSFQVFLKGYKDANIFLRFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPDWRSFPFGWLFLPVSLIGQPFSRKTRDHFLPLL-TSTAWWSGTLRRVFMFARQIAVMKGQAWNVVETLKGPLELTRR Klula1 VVEDCVHAIIEAGSSGSYFVFIKGVFKPKDEEPYGPFSPKWTKWLHRCLIPNLGYVCEAAASLLDRKLQVGLVPHTEIISLSSTSFY-VQTKLGSFQLFVHGFISADSFLNFRLQLER--LIILDYIMRNTDRGLDNWMVKLAAIDNGLAFPWKHPDWRSFPYGWLFLPVSILNMPFSNETREHFLPRL-LNTNWWEESFTHLFLWRKQWSVLKGQAFNVVETLKGPLELVKR Lacbi2 LAQSVRNAIITKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWIHRCLIPNLSYISEAAASLLDRRLDLHIVPPTELVSLSSPAFFYLPEKIGSMQFFLHGYQDASDFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPQWRSYTYGWLYLPVSIIGRPFSEKTRNHFLPLL-TSKSWWEETLENLFMFARQLAVIKGQAWNIVQSLRCPLELTRR Lenti61 YVQAVRDAIITKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWLHRCLIPNLSYISEAAASLLDERLSLDIVPRTQLVSLSSPAFFYLPEKIGSMQFFLHGYTDASDFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPKWRSYTYGWLYLPVTIIGRPFSQKTRDHFLPLL-TSKTWWRDTLRKLFMFRRQLAVIKGQAWNIVQSLRGPLELTRR Malgl1 -------AILCRYGPGPYGSS-------ANEEATGSV----------C---------EATA--------------------------Y-----------------------LRLELEK--LVVLDFLMRNTDRGLDNFMIRIGAIDNSLSFPHQHPQLRDYPYGWLFLPAGLIGQPFSDETRRLFLPKL-CDPVWWAGTLRRIFTFQHQVSLLLGQGWLIVQCLRGPIELCAR Mellp23 IVKDVRKAINLCGSSGSYFCKV-GIFKPKDEEPYGAMNPKWTKWFHRCLIPNLSYLSEAAASLLDRRLEAYIVPRTEVVHISSPTFFYLPQKPGSFQLFCTGFE-------FKHEMEK--LVILDYLMRNTDRGLDNFMIKVAAIDNSLAFPHHHPNLRDYSYGWLFLPVSLIGQPFSASTRAHYLRLL-TDPMWWAETLRQLFMFERQMALLKGQGWNVVESLRGPLELCRR Mnele LVVEAERAIIYQGSSGSYFVRV-GVFKPKNEEPYGHLNPKWTKWMQKCLIANQGYMSEAGASLVDRKLGLNIVPNTRVVALASETFNYLPPKIGSFQVFVNGYKDADYWVRFQHLFEK--LVCLDYIIRNTDRGNDNWLIKVAAIDNGLAFPFKHPDWRAYPYYWAWLPYANH--PFSEKTKELLLSKL-KDLNLVRELLHKLFLFDRQASVMRGQILNLCQALESPLQLVQM Monbr VIASVEQAIITQGSSGSYFCRV-GVFKPKNEEPYGALNPKWGKWFQRCLLQNAGYLSEAGASVVDTCLNLNIVPKTRVVRLTSPTFHYLPPKVGSFQQFVKGYKDATVFLRLQHQFEL--LVVLDYITRNTDRNNDNWLIKLAAIDNGLSFPFKHPDWRTYPFHWAWLPLAKR--PFSEETILRVLPQL-EREEFIEDMLYVLFKFEQQMAVMRGQIINLKTALQSPEQLVQM Morel2 IVDSVKEAIIAQGSSGSYFCRV-GVFKPKNEEPYGQLNPKWAKWIHRCLIPNLGYISESATSLVDRRLKLNIVPSTEVVWLSSSAFHYLPDKVGSFQLFLNGFKDANLFMRFREQFEK--MIILDYLIRNTDRGLDNWMIRVAAIDNGLAFPFKHPDWRSYPYGWLFLPRPLISQPFTKATRDHFLPLL-SSPVWWRETLRRLFMFDKQMAVMKGQGWNIVETLKGPMDLCRR Mucci2 IVQSVRTAIISQGSSGSYFCRV-GVFKPKNEEPYGRLNPKWTKWIHRCLIPNLGYLSEAAASLIDRKLGTMVVPYTDVIHMSSPSFHYLPPKIGSFQCFLTDYKDATVFFRFRREFEQ--LVILDYLIRNTDRGLDNWMIKVAAIDNGLAFPYKHPDWRSYPYGWIAMPDALVNRPFSEATRKQFLPIL-SDPLWWRDTMRALFMFQKQMAVLKGQGYNIIRTLKGPIDLVAM Mydma VIQATEEAIIYQGSSGSYFVRI-GVFKPKNEEPYGHLNPKWTKWMHKCLIPNQGYMSEAGASLVDEKLNLNIVPKTKVVRLASSTFNYLPPKIGSFQLFVEGYKDAEFYLRFQLSFEK--LVCLDYIIRNTDRGNDNWLINIAAIDNGLAFPIKHPDWRLYPYHWAWLPYAKV--PFSDEIKDLLLPRL-TDMCFVQTILYELFNFEKQMAVLRGQILNLNQALRTPAQLVQM Neucr2 IVDSVRTAIISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYVLDAQLRTHMVPYTDVVYLSSKSFHYLPAKPGSFQVFLKGFKDANLFLRFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPDWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLL-TSTAWWSQTLRRVFMFAKQIAVMKGQAWNVVETLKGPLELTRR Orpsp11 IVEEVKAAIIKQGSSGSYFCYV-GIFKPKNEEPYGKNNPKWSKWIQRCLVPNLGYISEAAASYIDRRLHLNIVPRTEIVSLASPSFYYLPKKKGSFQLFMTGYKDANIFFKFQWQFER--LVILDYLIRNTDRGLDNWMIKIAAIDNGLAFPYKHPDWRSYPYGWAFLPISQI--PFSAETRT-ILPLL-TSNSWWIETLEKLFMWKNQKAVMRGQGYNLIEVLNSPSGLVKR Pench1 IIESVRLAIISQGSSGSYFARV-GVFKPKDEEPYASRNPKWTKWIHRCLIPNLSYVSEAAAYVLDARLRTNLVPYTGIVRLSSKSFFYLPPKAGSFQVFLKGFKDANVFLRFREELEK--LVILDYIMRNTDRGLDNWMVKLGAIDNSLSWPWKHPDWRSFPFGWLFLPVSLIGQPFSQRTRDHFLPLL-TSTAWWSGTLRGIFMFARQIAVMKGQAWNVVETLKGPLELTRR Phybl2 LVESVRIAIISQGSSGSYFSRV-GVFKPKNEEPYGQLNPKWTKWIHRCLIPNLGYLSEAASSLMDRRLGTFIVPSTDVVHLASPAFHYRPPKIGSFQCFLHGYKDATLFLKFKREFEQ--LVILDYLIRNTDRGLDNWMIKVAAIDNGLAFPFKHPDWRSYPYGWLALPDYLVSRPFSSATRRQFLPLL-TDPVWWCETLKAMFMFANQMAVLKGQGYNIVRALKSPLDLVAL Picst3 LVNSITDVIIAAGSSGSYFIEA-GVFKPKDEEPYGPLSPKWTKWLHRCLIPNLGYISEAAACVLDRQLLSYIVPYTDVIYLRSPTFYYLPRKIGSFQVFLNGYSEAIAWFRFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDSGLAFPWKQPDWRSFPFGWLFLPLSIIGQPFSLRTRNHYLPLL-TSKQWWELTLRKVFLWLRQVAVLKGQAFNVVEILKGPLELTRR Plicr1 LSQAVRRAIITKGSSGSYFARV-AVFKPKDEEPYGRMNPKTTKWIHRCLIPNLSYISEAAASLLDERLDLHIVPRTELVSLSSQAFFYLPDKIG----------NASEFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPKWRSYTYGWLYLPVSVIGLPFSQKTRDHFLPLL-TSKAWWEETLRKLFMFRRQLAVIKGQAWNIVQSLRGPLELTRR Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 VVNSLKRSINQSGSSGSYFCRV-GIFKPKDEEPYGAMNPKWTKWAHRCLIPNLSYLSEAAASLLDRRLKTFIVPRTEVISISSPTFFYLPAKPGSFQLFCQGFQDASIFLKFRIEMEK--LVILDYLMRNTDRGLDNFMIKVAAIDNSLAFPHHHPNWREYAYGWLFLPASLIGQPFSRTTREYFLPLL-TSQQWWAETLRKLFMFERQMAVMKGQAWNIVESLKGPLELCRR Punst1 -----------------------------------------------------------------------MVPRTELVSLSSPAFFYLPEKIGSMQYFMHGFTDASDFLRFREELEK--LVILDYLMRNTDRGADNYMIKIAAIDNSLSFPHEHPKWRSYTYGWLFLPVSIVGRPFSEKTRNHFLPLL-TSKEWWAETLRKLFMFRRQLAVMKGQAYNIVQSLKGPLELTRR Rhior3 IVQSVHTAIISQGSSGSYFCRV-GVFKPKNEEPYGRLNPKWTKWIHRGLIPNLGYISEAAASLIDRKLGTNIVPYTDVIHLASSSFHYIPPKIGSFQCFLTNYKDATVFFRFRREFEQ--LVILDYLMRNTDRGLDNWMIKVAAIDNGLAFPYKHPDWRSYPYGWTAMPDALVNRPFSEETRHQFLPIL-SDPLWWRETMRGLFMFQRQMAVLKGQGFNIVRALKGPIDLVAM Rhoto1 LVSSVRLAINAKGSSGSYFARV-GVFKPADEEPYGTLNPKMVKWIHRCLVPRQSYLSESAASILDRHLGTNIVPRTEVVALSSPAFYYLREKEGSFQVFLKGFKDVSDFLYFRHELEK--LVILDFLIRNTDRGLDNFMARLAAIDNSLAFPHQHPLWRTFLYGWLNLPLSLIGQPWSASTRKAFLPKL-SDPEWWRDLLRSEFVWQRQWAVVKGQGWNLVESLKGPVELCRR Rozal11 VLNQVKQAIIRQGSSGSYFVRV-GVFKPKNEEPY-----------------------EASASIVDRRLKLNIVPRTEIVELASEAFYYYPNKIGSLQIFLKGFKNSNVQMKFQTNFEK--LVILDYVIRNT--GLDNWMIYITAIDHGLAFPFKHPDWRSYPFGWYFLSAAKV--PFSQQTIDLYLPIL-KDNKTITTMLKEVAIFQRQMALMRGQIHNLIRTFESPVDLVQK Sacce1 LVSDCIEAVIQTGSSGSYFVYV-GVFKPKDEEPYGPFSPKWTKWAHRCLIPNLGYICESAASLLDRRLETHLVPYTDTASIESFNFY-KQKKLGSFQLFLKEYINADEFFHFRLELEK--LIILDYIMRNTDRGLDNWMVKLAAIDNGLSFPWKHPDWRLYPYGWLYLPLQLLAKPFSEQMRSHFLPIL-TSTNWWEESFLALFMWKKQWAVLKGQAFNVVETLKGPLELVRR Salro MIASVEQAIILQGSSGSYFCRV-GVFKPKNEEPYGHLNPKWGKWIQKCLPQNQGYLSEAGASLVDQALGLNIVPKTKVVRLVSSSFHYLPPKIGSFQVFVRGFKDASEVLRLTRQFQH--MVVLDYLTRNTDRGNDNWLLRLAAIDNGLSFPKKHPDWRAYPYYWAWLYLARF--RFRDDIVEKLLPQL-RDETFIEGLLYLLFVFEKKKA------LNLTKALESPAELVRL Schco3 MVQAVKEAIIAKGSSGSYFARV-AVFKPKDEEPY---------------------ISEAAASLLDSRLKLNIVPPTQLVALSSPAFFYLPDKIGSMQIFMN---DATDFLRFRAELEKYLLTFVDYLMQNTDRGSDNYMIKIAAIDNSLSFPHEHPQWRSYTYGWLYLPVSIIGKPFSEETRNHFLPML-TSKTWWEETLEKLFMFSRQLAVIKGQAYNIIQSLKGPLELTRR Schpo1 LLDATKEAIISKGSSGSYFVKI-AVFKPKDEEPYGKLNPKWTKWFHRCLIPNTSYLSEAAACVLDRGLGLYLVPYTSVASISSPTFNYLPEKTGSFQQFLDGFVVASKFFAFRFEFEK--LVLLDYLMRNTDRNLDNWMIKIGAIDNSLAFPYKHPDWRSFPYGWLSLPRSLFTQPFTEFTRQLFLHKL-TSREWWEKLLRNVFMFSRQLSLVKGQAYNIVEVLKNIYDLLEL Sorma IVDSVRTAIISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYVLDAQLRTHMVPYTDVVYLSSKSFHYLPAKPGSFQVFLKGFKDANLFLRFREELEK--LVILDYIMRNTDRGLDNWMIKIGAIDNSLSWPWKHPDWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLL-TSTAWWSQTLRRVFMFAKQIAVMKGQAWNVVETLKGPLELTRR Sphar KLQDIKDAIIVQGSSGSYFCKI-GVFKPKDEEPYGSLNPKWTKWLHRCLIPNQGYLSEAGASIVDDALQLNVVPRTKVVKLASPAFNYLPPKTGSLQMFVAGYKDAIEMVGFQPQFER--MVVLDYITRNTDRGMENWLLKLAAIDNGLNFPFKHPDWRTYPYHWAWLPQARI--PFSEALVAKLMPLL-IDEAFVESMIHLTFLWLKQASVIRGQVMNLMQALKTPWQLLQL Spipu1 IVDEVRAAIISQGSSGSYFCRV-GVFKPKNEEPYGHLNPKWTKWIHKCIIPNLGYISEAAASYVDRRLQLNVVPRTEVVYLASPTFFYLPEKVGSFQVFLKGFKDATRFFRFQWGFER--LVVLDYLIRNTDRGLDNWMVKIAAIDNGLAFPWKHPDWRSYPYGWAYLPAARV--PFSRETRIQVLHLL-TSPTWWRETLERLFMWRRQRAVVRGEGYNLVETLRSPWGLVRR Sporo1 LVAKARLAVNSKGSSGSYFVRI-GIFKPSDEDPYGAMNPKLVKWVHRCLVPGQSYQSESAASVLDRHLESWIVPRTEVVGLTSQSFYYLREKQGSFQVFLKGFTDASDFFAFQCELEK--LVVLDYLIRNTDRGLDNFMIKLAAIDNSLAFPHTHPQWRQYPFGWLYLPLPLLDNPWSESTRARYLAKL-ESPEWWSELLRAEFLWQKQWSVVKGQGWNLVRSL--------- Stehi1 IVHSVKQAIITKGSSGSYFARV-AVFKPKDEEPYGRLNPKTTKWLHRCLIPNLSYISEAAASLLDTRLALNIVPPTQLVSLSSQAFFYLPEKVGSMQYFLHGYQDSSEFLRFREELEK--LVILDYLMLNTDRGADNYMIKIAAIDNSLSFPHEHPQWRSYTYGWLYLPVNLIGRPFSDQTRNHFLPLL-TSKAWWEETLRQLFMFNRQLAVIKGQAWNIVQSLRGPLELTRR Tapde11 VIDSVKEAIVTKGSSGSYFALV-GIFKPKNEEPYGQLNPKWTKWLHRCLIPNLSYISEAAACLLDRRLESNIVPPTDVVWLSSTSFNYLPAKQGSFQVFLEGYQDATEFLRMREELEK--LVILDYIMRNTDRGLDNWMLKLGAIDNSLAFPWKHPDWRSFPFGWLFLPASLIGQPFSAKTRQHFLPLL-SDPEWWCETLKKLFMFAKQMAVLKGQAWNVLETLKGPLELARR Thetr ILGKVKVAMVAQGSSGTYFVRL-GVFKPFDEGPYDKNNPKWLKWFHRCLPPNQGHLSEAGASIVDKHFNLSIVPHTRVVSLASEVFNYVPHKRGSLQVFMEGYEEATQLLPFQLQFER--LVIIDYIIRNTDRGSDNWLVRVAAIDNSLAFPYKHPDVRSYPYGWADMPQTDV--PFSAEIRTKLTPLLTHDSIQL--LLRRLFIFDAQMAVMRGQLYNLKKALKTPAQLIAL Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 VIESVRQAIISQGSSGSYFARV-GVFKPKDEEPYAAGNPKWNKWIHRCLIPNLSYVSEAAAYVLDYQLRTHLVPYTDVVWLSSKSFHYLPAKPGSFQVFLKGFKDANVFLRFREELEK--LVILDYIMRNTDRGLDNWMVKIGAIDNSLSWPWKHPDWRSFPFGWLFLPVDLIGRPFSQKTRDHFLPLL-TSTAWWSETLKRVFMFAKQIAVMKGQAWNVVEALKGPLELTRR Umbra1 VIHSVQEAIISQGSSGSYFCRV-GVFKPKNEEPYGHLNPKWTKWVHRCLIPNLGYMSEAATSLIDRRLQLNIVPFTDVIHMSSPTFHYLPSKIGSFQCFLNDFNDASMFLRFKREFEN--LAILDYLIRNTDRGTDNWMIRVAAIDNGLAFPFKHPDWRSYPYAWLSLPHALLVQPISVETRKRLLPML-SDPEWWEGTLHRLFMFERQLAVLKGQGWNIVQTLRGILDLVTR Ustma22 QVEQVKHAIITTGSSGSYFARV-AVFKPKDEEPYGNLNPK--RQFARCLIPNFSYLSEVGASYLDARLALQMVPRTELVELSSPSFHYLPIKIGSYQTFLKGYVNASDFLRFRLQLER--LVVLDFLMRNTDRGLDNFMIKIGAIDNSLSFPIKHPNIRQYPFGWLFLPSDLIGLPFSDSTRQHLLPIL-NDPVWWQHTLRGIFKFEKQMSVLRGQGWNLVQSLQGPLDLCAR Walse1 ---------ILKGSSGSYFARV-GVFKPKDEEPYGRLNPKWTKWAHRCLIPNLSYISEAAASILDDRLQLGIVPRTGLVDLASPSFFYLPDKIGSLQTFMHGYKDASNFLAFREELEK--LVILDYLMRNTDRGLDNFMIQIAAIDNSLSFPHQHPKWRSYTYGWLFLPVSLIGQPFSASTRRHFLPLL-SDPKWWTETLRQVFMFARQMAIVKGQGWNIVQSLRGPLELCRR Zygro1 VVSECLDAFIKAGSSGSYFVYL-GVFKPKDEEPYGPLSPKWTKWMHRCLIPNLGYICESAASLLDERLGLGMVPPTDTVVLESHRFY-LQKKLGSFQLFLYDYMGAEEFLAFRLELEK--LIILDYIMRNTDRGLDNWMVKLAAIDNGLTFPWKHPDWRSYPYGWLYLPVHMLAQPFSESTRRHFLPLL-TSEQWWSESFTALFMWRKQWAVLKGQAFNVVETLRGPLELVRR [Cluster2264.fasta_al_trimmed; alignment length = 123] Allma1 RHVSDVHFEIADLVKGVYEGGLKTWECSVDLAILELGCGSALPSLAILMTLQDYNAEVLQVVTAPNVLLSFVAGDWGDVILTSETIYDEATVPALLELMLVAAKTFYFGVGGGVRAFREILEL Ashgo11 RELFDVKHQLMDVRKNVYEGGLKSWECSLDLVIAELGCGTALPSQYLFLLLSDYNESVLRLATLPNLIITFISGTWSLLLLTSETIYQPETLPVIAELIYAAAKDIYFGVGGSVAEFRSIIAI Aspfu1 REVFDIRTQLMDIKPNFYEGGFKTWECAVDLAIIELGAGTSVPSLTLFFTFADYNSAVLRLVTLPNLLLTFISGAWSTLILASETIYSPASLEPFSETLLIAAKKVYFGVGGGVDEFRVILKI Aurde31 RDLFDARFQLMDLVRGVYEGGFKTWECASDIVVLEAWCGTAVPSAYLLVHLQDYNQLVLELVALPNLILAFFHGSWSDLVLSSETVYEPSSLPALVALLLIAAKRVYFGVGGGVREFRAILDV Batde5 RSVSDVKFQIADLISGVYEGGLKTWECSIDLVVLELGCGSALPGIYCLVDFQDYNEPVLRMVTIPNILLNFYSGDWKDVILTSETIYEAQCQADLFKLILVASKSVYFGCSGSLNDFREITQL Botbo1 RDLFDARFQLIDLVPGLYEGGLKTWECSLDLIILDVGCGTALPSVYLLIHLQDYNRSVFELVTLPNIILAFFTGSWADLVFTSETIYRLESLPSLIRLLLVAAKLLYFGVGGGVDSFRRIMRI Botci1 RELWDVRAQLMDVKTGVYEGGFKSWESSVDLVVLELGCGTALPSLAVFLGLADYNPTVLQLVTLPNILLSLFSGAWSTIIIGAETIYSPVALKAFAETLLIGAKKVYFGVGGSIEDFRAVIEV Caeel KELENMETS--DITVHKYEGGFKIWECTVDLCVLELGCGAALPSILTAVFAQDFNASVIEFFTLPNFEEN-----WEDFILSSETIYNEDDYQALHDAVWFAAKFFYFGVGGSVPAFRRIVEI Canalb1 --------------------------------------------------------------------------------------------------------------------------- Cangl RELFDVKHQLMDVRKNVYEGGLKSWECSIDIIIFDMGCGTALPSTFVFLILADYNKSVLELVTLPNLIITLISGSWGLLVFSSETIYQPENLPVVAETLLVAAKDIYFGVGGSVIEFRSIVAL Capow AECSRAAIQVCDVVPAVYEGGLKVWEASLDLLVLELGCGTALPGIYAL--FQDYNAEVIQHVTIPNVLLNFSSGDWRDVILSAETIYSPANYNALITAILLASKTYYFGVGGGTREFREILSV Catan2 RHISDIHFAIADLIPGVYEGGAKTWECSIDLAVLELGCGSAVPSLRSC---------------------------WV----------------------L----------------------- Cioin --------------------------------------------------------------------------------------------------------------------------- CocheC53 RELFDVRLQLMDLQQNVYEGGYKTWECSLDLVVIEMGCGSALPSLLLFFTLTDYNADVLRCVTLPNLVLAFLSGSWATFILGSETIYSPASLTAFADAILVAAKRVYFGVGGSVDDFRCLVEV Coere1 --MDDVQFQLADVIRGVYEGGLKTWECSLDLLVLELGCGTGLPSLHVLVCMQDYNRDVIELITIPNVLANFISGDWADLILTSETIYDTTNYKKLHDLLLVAAKSIYFGLSGSVLTFREILRM Conco1 RTLPDIRLQLADVIQGVYEGGFKTWESSVDLSIIELGCGSSLPSLTILLHLSDFNLQVLRLVTVPNLIGNCFYGDWNDMIITSETLYTPTVIHNLYNNLYVAAKTVYFGCGGGTLGFREILLV Conpu1 RDLFDARFQVLDLLPRVYEGGLKTWECALDL-VIEVGCGTAIPSLYVLVHLQDYNASVLELVTFPNIFLAFFAGGWSDLVLTAETVYRADGLRPLVRVLLVAAKVVYFGVGGGVVEFRAILRV Copci RDLFDARFQLIDLLPGVYEGGLKTWECSLDVVVLELGCGTAVPSLYVLIHLQDYNDSVLELMTLPNVFLTFFSGAWEDLLMTSETIYRTESLVPLTRILLVAAKVLYFGVGGGISEFRRVLSI Croqu1 RDLYDAKYQTYDLLPGVYEGGFKTWESSLDLILLEVGCGTALPTVWLLFYLQDFNEEVLYLLTLPNIILAFFHGPWRELIYSSETIYSPITLPSLVSLFLVAAKKVYFGVGGSSFEFRLIMSV CryneH991 RDLFDARFQLIDLIPGLYEGGLKTWEGGVDLVVLEVGCGTSLPTAFLLLHLQDYNQLVLSLVSLPNLILAFTYGHWEGLVLTAETIYSQDSTPALIDVLLVAAKVLYFGVGGGLQAFRKVVQI Crypa2 RELWDVRVQLMDVKTGIYEGGFKSWESSVDLVVIELGCGTALPSLALFLTLADYNPSVLRLVTMPNFLLAFVSGGWSTLVLGAETIYSPFALNSFTETLIVAAKRLYFGVGGSLDDFRGVVRC Debha1 RELFDVKHQIMDLKKNVYEGGFKSWECSYDMVLLEFGCGTALPTCFLFYILSDFNYDVLRLVTVPNLIIHFVSGSWG-LIITSETIYSPESLPIVAESLLIASKNFYFGVGGSVTEFRSLVTL Dekbr2 RELFDVKQQLMDLKHGVYEGGLKSWECSYDLICIELGCGTSLPSLYIFFILSDYNIEVLRLVSLPNILVNFVSGSWCNLILTSETIYSPPILPIVGEMLILTAKDIYFGVGGSVNQFRSIITI Dicdi KKLVKP---FKDLIPGVYEGGFKLWECSIDIIVLEIGCGHGLPGIYCLVTFQDYNEEVIYNLTQPNVLINYISGDWKDIILTSDTLYNVGSFKKLYNLIYLASKTYYFGVGGGIRKFREVVEI Dmel LNAKEMEVG-KDLISGVYEGGAKIWECTEDLLVLDLGCGCGLLGIYAMVDFQDYNKDVLEYITYPNILLNLYSGDWSDLILTSETIYNIANQQKLLDTFLVAAKSHYFGVGGGLEQFRGILQL Enthi -----------TIKTGVYEGGFQIWEGGDDLYVLEVGCGQALPSVLLKVDVADYNSDVLELTKL------FISGDWDDYIIGGDVTYNPEYQPKLAHLLIIAAKVVYIGNGGRIVDFRLIVTF Falba RNAVDFESTFTDLLPGVYEGGFKSWEASTDLTVLELGCGSALPGIFLLVDFQDYNADVIHQVTLANIALNFFTGDWADLLLLSETIYSLANYQKQIQLILVAAKNHYFGVGGNMMDFRSILKV Fomme1 RDLYDARYQLIDLIPGVYEGGLKTWECSLDLVIIELGCGTAVPNLYLLIVLQDFNDLVLRLVTFPNVLLQFIAGSWQDITLTSETIYETSSLPSLIALLLIAAKVLYFGVGGSVMEFRKVMSI Fusgr1 RELWDVRVQLMDVKTGVYEGGFKSWESSVDLVVMELGCGTALPSLAVFLILADYNPSVLQLVTLPNFILSFMSGAWSTLILGAETIYSPFALQAFLETLYIGAKRLYFGVGGSLDDFRGVVEC Galma1 RDLFDARFQLIDLVPGVYEGGLKTWECSLDLVVLEVGCGTGVPSSYIFIHLQDYNVSVLQLVTLPNILLTFFSGSWDDILLTSETIYRTDSLDPLVNLMLVAAKILYFGVGGGVSDFRKIMRV Ganpr1 REISDIKFQLADLIPGVYEGGLKTWECSLDLVVLEIGCGAALPGIYCLVDLQDYNPAVLSLVTAPNVLLNFYSGSWSRVILTSETIYNISHHEDLLNLILVAAKTNYFGLSGSIFTFREIWLL Gloin1 RHLSDVKFQLADIVQGVYEGGLKTWECSHDLVILELGCGSSLPGIYILVDFQDYNKQVLKLVTIPNILLNFFMGDWSDLILSSETIYNTDSLPKLYNVILIAAKSIYFGVGGGVLPFREILML Hisca1 REVFDIRAQLMDLKPTVYEGGLKTWECAIDLAVVE-------------FVFADYNAAVLRLVTVPNILLTFVSGAWSLLILASETIYSPSSLRSFSETLLIAAKEVYFGVGGGVDEFRVVLEV Klula1 RELFDVKHQLMDLRRNVYEGGLKSWECSIDLVIIELGCGTSLPSEFLFFTLCDYNESVIRLVSIPNLIVSFISGSWGTLILTAETIYQPDTLPVISETLLLAAKDIYFGVGGSIVDFRSIVLI Lacbi2 RDLFDARFQLIDLVPGVYEGGLKTWECSLDLVILELGCGTAVPSLYILVHFQDFNLSVLELVTLPNILSTFFSGSWSDIILTSETIYSTSSLPSLVDTMLVAAKVLYFGVGGGASEFRKVMSV Lenti61 RDLFDARFQLIDLVPGVYEGGLKTWECSLDIVVIELGCGTAIPSMYLLVHLQDYNGLVLRLVTLPNVILAFFSGSWADILLTSETIYRTASLQSLVNLMLVAAKLVYFGVGGGVSEFRSVMRV Malgl1 REL-----------------------------VL--GCGTAIPSCYIFLSLCDYNEEVLSLVVFPNLFLAFFSGGWDDVVLSSETVYSLTNLHSLCRVLLVAAKVLYFGVGGGIDAFRVVLQI Mellp23 RDLYDAKYQTYDLIPGVYEGGFKTWESSLDLIVLEIGCGTALPTVWFLFHFQDFNPE------------AFFYGPWHDLSYSSETIYSPDSVLSLVDLFLVACKSVYFGVGGSSYEFRLIMKV Mnele --MKDVDTSSIDLIPGVYEGGFEVWECTVDLLVLDLGCGSGLLGICAKVHFQDFNSEVITNFTIKNYHKNFCAGDWSDLILTAETIYSVDSQKKVM--------------------------- Monbr LELGEATIQLLDVVQDEYEGGLKLWECSLDLA----GC----EGLH---------------------VLE-------DLIVSAETAYSLASIDGLVELILAANKNYYFGVGGGVRALRSIVK- Morel2 RNLEDVKFQIIDLVKGVYEGGLKTWECALDLVVLELGCGSALPGIYVLVDLQDYNDQVLKFVTLPNVLLNFFLGDWSDLILTSETIYAEESHQKLYATILVAAKTFYFGVGGDILSFREILEL Mucci2 RTLADVKFQMADLIKGVYEGGFKTWECSIDMVVLELGCGSSLPSLYLLVDVQDYNDQVIRFITIPNILLNAFVGDWSDMIVTSETIYAEHALPDLISVFYVAAKTVYFGVGGGILPFREILKV Mydma --------------------------------------------------------------------------------------------------------------------------- Neucr2 RELWDVRVQLMDVKTGIYEGGFKSWESSVDLVLMELGCGTALPSLALFLVLADYNPSVLYLVTLPNFILAFLSGGWSTLVIGAETIYSPFALESFAATLIVGAKKMYFGVGGSLDDFRGVVRC Orpsp11 RNVSDIKFEIADIIPGVYEGGLKTWECSIDLVVLELGCGSALPGVYCLVDFQDYNQEILSLVTIPNVLINFWYGDWD---------------------------------------------- Pench1 REIFDIRTQLMDITPNFYEGGFKTWECALDLAIIELGAGTAVPSLTLFFTFADYNSDVLRLVTLPNLLLTFVSGAWSTLVLASETIYSPASLAAFSETLLVAAKKVYFGVGGGVDEFRVVLEV Phybl2 --------------------------------------------------------------------------------------------------------------------------- Picst3 RELFDVKHQVMDLEKRVYEGGFKSWECSYDTVYLDFGCGTSLPSSFLLVILSDFNQEVLRLVSLPNILIHFISGSWG-FIISSETIYSLETLPLVAESILIAAKNIYFGVGGSVIEFRSMIDI Plicr1 RDLFDARFQLIDLVPGVYEGGLKTWECSLDVVVLELGCGTAVPSLYILIHLQDYNRSVLELVTVPNLILALFSGAWDDLVLTSETIYSSHALPALVTLLLVAAKILYFGVGGGVSDFRRVMRV Polpo KKLAKPLVSLSDLIPGVYEGGFKLWECAIDLVVLEIGCGHGLPALYCLVTLQDYNQEVIDTLSIPNLKLNFISGDWKDLILTSDTIYNISSFKKLYNLILLAAKSFYFG--------REIIGL Pucgr2 RELYDAKYQTIDLIPGVYEGGFKTWECSLDLAILEIGCGTAVPTVSLCILLQDFNAD------------ALIYGPWSEVIMSSETLYSTASLPDLINVLLIASKSVYFGVGGGTHSFRVLMDV Punst1 --------------------------------------------------------------------------------------------------------------------------- Rhior3 RTLADVRFQLADLIKGVYEGGFKTWECSIDMVILELGCGSSIPSLYLLVDIQDYNEQVIRYVSIPNILLNAFFGDWSDMIVTSETIYAEHSFSDLTRVFW----------------------- Rhoto1 RDLFDARFQVLDLVKGVYEGGLKTWECSLDLVILEVGCGTAVPICALFIHVQDYNKQVLSLITLPNILLTFFDGDWADLVLTSETVYSLSSLEPLLNLLLVACKRIYFGVGGGELEFRTVLSV Rozal11 RTLSDVEVDIADLIPGVYEGGLKVWEASLDLVCIEIGCGAGLPGIYLSVDFQDFNEQVLKSVTIPNILLNFIPGDWDDLLITSETIYDLNKYDSLLRLFIVAAKRYYFGLGGSTNIFREIILF Sacce1 RELFDVKHQLMDLRKNIYEGGLKSWECSYDLVVVEIGCGTALPSEFLFFVLTDYNASVLRLVTIPNLVITLISGSWGVLSLSSETIYQPDNLPVIAETIYVAAKDIYFGVGGSITEFRSIICI Salro -----------DVKAGVYEGGFKVWECTFDLLVIELGCGAGYPGLLALVDFQDYNRCVIDKWTVPNVLANFFAGDWADVVMMAETVYA----QSSLQPLLLAAKACYYGVGGSVAAFRVIMKY Schco3 RDLFDARYQLIDLVPGLYEGGLKTWECSLDLVVLEIGCGTAIPSLYLLITLQDYNASVLELITLPNLLIALVSGSWEDMVLTSETIYRTESLDALIGIMLVAAKVLYFGVGGGVPDFRKVLRV Schpo1 RELWDVKMQLMDLVPNVYEGGYKTWECSLDLAVLELGCGSAIPILSCFLVFQDFNVDVLRYVTLPNLLLNFLCGCWSSLVLASETIYSLPSLENFLYMLLVAGKDLYFGVGGSILEFRSIVYW Sorma RELWDVRVQLMDVKTGIYEGGFKSWESSVDLVLMELGCGTALPSLALFIVLADYNPSVLYLVTLPNFLLAFLSGGWSTLVIGAETIYSPFALESFAATLIVGAKKMYFGVGGSLDDFRGVVRC Sphar KVLENTTYELADLIPGVYEGGLKTWECSLDLLVLELGCGSGLPGVYMIVDFQDYNEEVLTHVTIPNVVLNFYSGDWSDIVLTSETIYEPSLNKVLLATILVAAKSYYFGVGGSMTAFREILQI Spipu1 RNVADIKFEIADLIPGVYEGGLKTWECAVDLVVIELGCGSSLPGIFCLVDFQDYNEDVLRLVTIPNVLLNFWAGDWGDIVLTSETIYASESHARLLDLIFVAAKTTYFGCSGSLPTFREVVRI Sporo1 --------------------------------------------------------------------------------------------------------------------------- Stehi1 RDLFDARLQLIDLVPGVYEGGLKTWECSMDLVVLEIGCGTAVPSLYLMFHLQDYNRSVIELVTLPNIILAFFIGSWDDIVLTSETIYRSESLQALLRVLLVAAKVLYFGVGGGVQDFRKIMRA Tapde11 RELWDIKHQLMDVIKGVYEGGFKTWECSLDLMIFEVGCGTAVPSTYLLLVVQDYNLPVLQLSTVPNLFLALLTGPWSDLILASETIYSTANLPAFTSLVLVAAKRVYFGVGGGVEEFRTIMQV Thetr TELDGVRIEVEDLAAGLYEGGLKVWEATLELIVLDLGCGHGLAGIYALVTFQDYNAAVLTMVTAENVYLNFVAGDWGDVIVSAETIYARESYPKLLGVLLFAAKSYYFGVGGGVVEFRQVLRI Treme1 RDLFDARFQFADLVPGVYEGGLKTWEGGMDLVVLEVGCGTALPSAYILIHLQDYNHLVLSLVTLPNLILAFSSGDWSDLVLTAETIYSEGSVMPLLDVLLLAAKVLYFGVGGGLQSFRRVIRI Trire2 -DLWDVRVQLMDVKTGIYEGGFKSWESSIDLVVIELGCGTALPSLALFLILADYNPSVLRLVTLPNFLLAFISGAWSTLMIGAETIYSPFALQAFAQTVYVAAKRLYFGVGGSLDDFRGVVHC Umbra1 RTLADVKFQIADLIKGIYEGGFKTWECSIDLVVLELGCGSALPGIYLLVDFQDYNEQVLQYITIPNIILNCYFGEWQDMIVTSETVYSEESIPGLVKVLYVAGKTVYFGVGGGILPFREILKI Ustma22 RDLFDARFQMLDLVPGVYEGGLKTWECALDLVILELGCGTSLPSVFLLLHLADYNAQVLQLVTLPNLILAFYSGAWSDIILTSETIYSLHSLPALVELLLVAAKVIYFGVGGGVESFRTVLSV Walse1 RDLFDARFQLIDLIPGKYEGGLKTWECSVDLVLLEIGCGTSLPSLYAYIHFQDYNLQTIQLVTFPNIFLTFSYGAWKDYIFTSETVYRTASIPTLVELILIASKSVYFGVGGGVREFRHILSF Zygro1 RALFDIKHQLMDLRKNVYEGGLKSWECSIDLVVLELGCGTALPSLYVFLILSDYNKSVIRLVTLPNLIITFISGSWGLLNLTSETIYQPENLPVVAETLLVAAKDIYFGVGGSIVEFRSIVYI [Cluster2265.fasta_al_trimmed; alignment length = 275] Allma1 VRPTAHLIPVARIDPTNQHVHLADRTLSYDYLVVAPGLTLRWDKISGLAEAIGVVSNYHVQALKG-RALFTMPSTPIKCAGAPQKIAYLAEEHWRQNGYLAGGPIFAIDKYA-AALTDVHELVAVDRIATFQYDLLHATPQMAAPAFLAD-SQLTD--AAGFVAVDRETLQHGT--FPSVFALGDASSVPTSKTAAAAAAQAPIAVANILAHMSGARYDGYTSCPLVTGRKSLILAEFSPMETFDQAVERFHLTAVLPEVYWHGLVNR-GWWKGP Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 RQPLNGLLDVHTFSPENNFITLANGKVNYEHLVVVPGIKVDFSSIKGLPEALLVSSIYGIEKLQG-TAIFTQPAGVIKCAGAPQKVMWLALDYWKRAGFATALPMFGVPKYS-AKLEELHDLVSIDDKATFRFDFLHVVPKMGAHAFVKN-SPLAN--EAGFVDVDDNTTRHKK--YGNVWSAGDASSLPTSKTAAAITAQAPVLVSNLLRTMEGSSYDGYTSCPLLTEYGKVLLAEFKPKETFDQATPRYHLKKFFPWVYYNYMV-K-GTWGGP Aurde31 RKKLASILPVQSFDPANNAVTLDSGRVQYEYLVVAAGLKINWNGIAGLEDALGVSSIYSIDSLRG-TAVFTQPAGVIKCAGAPQKIMWCAWDRYRRQKFWTGMPMFSVPKYS-DALNALHNLVAVDRKATFEFTILHVTPPMGPLDVLKS-SPLAD--ATGWIDVHPGTLRHNKPGYGNVFALGDCSSLPTSKTAAAITAQTPVLVDNLFHVATTAIYDGYTSCPLITGYDQLMLAEFKPQETFDQVVPRFHLKKFFPYVYWKLMT-K-GMWFGP Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 RRRLTSLIPVASFSPETSSLTTTSGSLSYDTLIVAAGLKINFEAIENLPKALGVSSIYSISSLRG-KAVFTQPAGIIKCAGAPQKIMWMAWDWYRRNNFISGMPMFSVKKYS-DALNALHNLVSIDRVASFDYTILHVTPPMGPHDFIKS-SPLAD--AAGWVDVDPATLQHKKPEYKNVFSLGDCSSLPTSKTAAAITAQTPVLVENLTKFLETAAYDGYTSCPLLTGYGELMLAEFVPKETFDQVTPRYHLKKFFPWVYYDRMV-N-GRWFGP Botci1 RKPLKDLIDVEGFSPDENFITLKNGIVNYDQLVVAPGITVDVGSVKGLFEALLVSSIYNIQKLQG-KAIFTQPAGVIKCAGAPQKIMWLALDYWKRAGFATGLPMFGVPKYS-ATLEELHDLTAIDNRAIFEFDLLHVVPKNKPHDFVKN-SVLAN--DAGYVNVDEGTTRHIK--YHNVWSAGDASSLPTSKTVAAITAEAPVLVRNLLLAIDGQIYDGYTSCPLLTEYGKVLLAEFKPKETFDQAIPRYYLKKFFPWVYGKYMV-K-GTWGGP Caeel --------------------------------------------------------------------------------------------------YATSLKLFGIESYL-KSLEKVRNLIEVNRIATFEYSLLHIGPPCSTPEALRN-SAFVD--KTGFMDVDGGSLQSKK--YPNVFGVGDCMNTPNAKTAAAVSSHLKTIEKNLTQVMQGMQYDGYASCPLVVSTNRVILAEFGAMETTDQSKPTYLMKRFMPALYWNGLI-K-GYWNGP Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 VAPTSSLLPVTRVDPTAKLVHTSNGALAYDYLVLAPGIESQWDKIKGLSEALPVVSNYHFKALKG-NAVFTMPSTPIKCAGAPQKIMYIAEEYWRESSFYSGIGIFAIDKYA-AALTQIHDLVAIDGTATFPFDFLHAVPPMGPPAWLAA-SGLASPTSNGFISVNQHTLQHSV--YPTVFALGDATSAPTSKTAAAIAAQSPVLVRNLLAHMSGAQYDGYTSCPLVTGRKSLILAEFSPMETFDQAQESYQATAAIPWVYWKGLVTG-GWWKGP Cioin QKSMKDVIPIQQFDPENNQVILGNGKVSYKYLVVALGIKLQFDRIKGLPEAFGVCSNYSLQDFTG-NAIFTFPTPPLKCPGAPQKIMYLADEYLRKHGFNSAGPIFAVKKYA-ESLSKVLNLVEVKKEAIFKYEMLHVSPPMSPHEVVKT-SGLAD--AAGFVEVNKETMQHVR--YPNVFSLGDCSSVPTSKTAAAVASQNAILSKNLLSVMSGPLYDGYTSCPLITGYSKCILAEFDPLETFDQGKQRYHMKAVMPAIYWDMML-K-GRWSGP CocheC53 RTPMNDLVDVASFSPNNNLLTLESGVIHYDHLVVAPGIKIDYGSVKGLSEAMPVASIYSIQKLKG-SAIFTQPAGVIKCAGAPQKIMWLALDHWRRSGFATGLPMFGVPKYS-AKLDALHDLVSISNTATFPFSFLHVAPKNVPHEFVKA-SPLSN--EAGYVDVDPQSLRHLK--YPNIWSLGDAANLPTSKTVAAITSQAVVLTQNVLRSLDGEEYDGYTSCPLLTGDKKVLLAEFKPKETFDQAVPRYHLKKFFPWVYDRFHV-K-GQWGGP Coere1 RRPMADVMPAAAVDPAANAVTLADGRLAYDYLVVAAGIQLDFGAVRGLPEALGVASNYSLQRLRG-NALFTMPATPIKCAGAPQKIAYLAEELLRERGYYSALGIFGVDKYA-AAMSRVQDLVAVDNTATFSYEFLHVTPPMKPFDFLSS-SPLAN--AAGFVDVHPHSLQHVR--FPNVYSLGDCSSLPTSKTAAAAAAQSRVLKHNLLSQIEGAEYDGYTSCPLVTAKHKLVLAEFSPHETFNQANEHYWLTAVLPEVYWKSML-K-GTWCGP Conco1 KRSTASVIPVAELNPDQSKVVLADGSISYDFLVVATGLENKWDKIKGLQESIGVVSNYSLSELKG-NALFTMPSTPIKCAGAPQKIAYLADDYLREKNYFTGIGIFAIEKYG-NQLTKISELIEIDRVAKFKYNFLHVTPPMSTSEFVKK-SPLAN--EGGFVDVDKLTLKHVK--FDNVYSLGDVSSLPTSKTAAAITEQSGVLAANLTNALQNLEYSGYTSCPLITGKGKLILAEFSPLETFDQSLERYILTKIIPEVYWNGLL-K-GRWSGP Conpu1 RRPLQSLIPVQSFSPDKSSVKTTSGTLSYDVLVVAAGLKTNWDSISGLSNALGVSSIYSIDGLRG-RAIFTQPAGVIKCAGAPQKIMWMAWDRYQKTGFRTGMPMFSVKKYS-DALNELHNLVSVDRKATFDYTLLHVSPPMGPLDFIKS-SPIVD--ATGWVEVDPATLRHVKPEYGNIFALGDCSSLPTSKTAAAITSQAPVLTENLFSVVDSAKYDGYTSCPLLTGYGELMLAEFKPKESFDQRQRRYHLKKVFPWAYWNGMI-K-GTWYGP Copci RRPLDSLIPVSTFSPNTSSVTTTAGEVKYDYLVVAAGLGINWEGIKGLPSALGVSSIYSIEGLRG-KAVFTQPAGVIKCAGAPQKIMWMAWDRFRRTGFYTGMPMFSVKKYS-DALNKLHNLVSVDHKATFDYTTLHVTPPMGPLKFIKD-SPIAD--QAGWVSVNQNTLQHTNPDYQNIFAIGDASSLPTSKTAAAITAQAPVMVENLFSFINSARYDGYTSCPLLTAYGELMLAEFKPKETFDQSKSRYHLKKVFPAAYWNYMV-Q-GKWFGN Croqu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 RRPVSSLIGAAGFEPGANQVVLADGKIGYDYLIVGAGLQINWDNVKGLTAALKVSSIYSIRNFKG-EAIFTQPFGVIKCAGAPQKINYMADYWWKSQNFITGMPMFSVPHYS-KALDALTNLVEVRKTAVFEFGLLHAVPPMGPLKAIKE-SPLAD--SVGWVDVDQGTLQHKK--YENVFSLGDSSSLPTSKTAAAITGQSPVLTHNLVALMETAIYDGYTSCPLFTGRGSLLLAEFKRKETFDQSVPNYHLTKVIPRAYFSKML-K-GEWYGP Crypa2 SRPLSSIIPVSKFDPENNELKTTDGEVSYEYLVVAPGLEVNFGGVKGLPEALNVSSIYSIQGFKG-TAIFTQPAGVIKCAGAPQKIMWMALSQWEKDGFATGAPMFAVPKYS-KALEELHNLVGVDKTATFEFGFLHVVPPQKPWNWVAK-SPLAD--SAGWVDVDKTTTQHNK--FTNVFSIGDASSLPNSKTAAAISSQAPVLVDNLLAAIRGAGYTGYASCPLLTGHNELMLCEFKPDETFSQDVPRYHLKKFFPSVYWNSFV-K-GTWYGP Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi EKDEKDFIPVTVFKPEENIVLTKDGEIDYDYLVVSTGLELYWDRVKGLKENLGVTSNYSIKSLKGNVAIFTVPTTGVKCGGAPQKILWLCDDYLRKHGFNSAGAMFPVKKYS-EVLDKMHNLVEIKKEAVFKYDMIHVVPPMGPHSVIKN-SPLADP-ATGFVNVDKGTLQHVK--YDNVFSLGDTSNLPTSKTAAAITSQAPILVGNLINHKLGHKYDGYTSCPITTSYSKIILAEFKVDESLDQSKESMFLKKVFPTAYWEGML-K-GRWFGK Dmel HRQMADVLPALEFDPDNNTVSTSGGTIKYDFLIIATGLQLNYGKIPGLVEALNVCSIYSLRRTNG-NAIFTFPNCPIKCAGAPQKIAYISEHYFRKMGYNTSLPIFGVKHYA-EALMKLRNLVEVRNIAVFTYSMLHVTPPMSTPDVVANCKKLVT--PTGFVDVDQLTLQHNK--YSNVFAIGDSASSPNSKTAAAAAAQSPVVFKNVMAAIEGDIYDGYSSCPIVTGYSSCILAEFDPVETFDQSKERFFMKKLMPVLYWKLMM-N-GYWNGP Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----QRLMPMLMERPEFAAAPLSFSYLSRKHKIASGGEPTTGLGSDGAIKSLTLRNNLNLRSLD--PARFTQ----------------------RRLGF--GLPIAPVPKTG-RQLRKI--------------------------------EAEAR--GRGYL---PRTLRIIR---------------------------------------------------------RALAADFS----------------------------QNGL---- Fomme1 RRPLASLVPVKSFEPRSSSITLASGTLGYDILVVATGLQVNWNGIKGLSQALGVSSIYSIDALRG-KAIFTQPVGVIKCAGAPQKIMNMAWDRYRRTQFWTGTPMFSVKKYS-DALDKLTNLTSIDRIATFDYSLLHAVPPMGPLDFIKN-SPIAD--QAGWVSVDDATLQHKNPEYANVFAIGDCSSLPTSKTAAAITAQAPVLSENVFSLVDTAKYDGYTSCPLLTDYGYLMLAEFKPKETFDQATPSYHLKKFFPWIYFEAMV-K-GDWYGT Fusgr1 KMNMPELIDVNGLTPEDNSITLGTGKVNYEHLVVAPGIKINYDSIKGLPEALSVSSIYGIQRLQG-NAIFTQPAGVIKCAGAPQKTMWLALDHWKQTGFATGLPMFGVPKYS-AALEQMHDLVEINDKAIFQFDFMHVVPKMGPHAFVKN-SAIAN--EAGYVAVNDNTLRHNK--FTNVWSAGDASSLPTSKTAAAVTSEAPVLVSNLLRAIDGPAYDGYTSCPLLTEYGKVMLAEFKPKETFDQAVPRYHLKKFFPWVYKNYMV-K-GTWGGP Galma1 SRPLVSLVPVKTFSPDSSSVTTTAGDIAYDTLVVATGLQVNFDAIQGLPDALGVSTIYSIENVKG-NAIFTQPSGIIKCAGAPQKIMWMAWDRFRKTGFYTGMPMFSVKKYS-DALNELHELVSIDRKAIFDYSLLHVTPPMGPLNLFKG-SPIAD--AAGWVAVDKATLQHVKPEYSNIFAIGDCSSLPTSKTAAAITAQAPVLTENLFSFVDSAKYDGYTSCPLLTGYGELMLAEFKPKESFDQKKSNYHLKKVFPYAYWNYMV-N-GQWFGS Ganpr1 SKPTRELIPVSKVDPVKQTVSTDDGTVKYDFLVVAPGISLDWDKVPGLVSTLGVTSIYSIRGFQG-NAIFTQPATPIKCAGAPQKIAYLAEEIFRSNGFNTGMGIFSSDYYG-EALTKITNLLAIKKEAVFKYSLLHVVPPMSAPKFIGE-SGLGN--ADGWCNVDKHTMQHAK--YPNVFSLGDASSLPTSKTAAAITAQAKYLADNLLAVIGGNKYDGYTACPLVTGKNKLVMAEFSPLETFDQRTESYTLKTVFPALYWDYML-K-GVWDGP Gloin1 AKPTEELIPVAKVQPDNKLIELTDGKIGYDYLVVATGLECHWDKIRGLPETLGVTSNYSIREFKG-NAIFTMPSTPIKCPGAAIKVAYLAEDTFTKNRYNSAMGIFSIDKYA-KSLERVTELKEIRKEAVFNYDLLHVTPPMGPPSFIGE-SGLGN--KQGYVDVDKYTLQHVK--YPNIFSLGDSSSAPTSKTAAAISVQSGVLKKNLLDTMTGAKYDGYASCPLLVGRDKLILAEFSPLETFDQGQERYWLTKVIPEIYWNGLL-K-GTWTGP Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 RRPLDSLIPVQSFSPTTSSVTTTSGQLSYDTLVVAAGLQINWNGIKGLTSALGVSSIYSVEGLRG-NAIFTQPAGIIKCAGAPQKIMWMAWDRYRKTGFYTGMPMFSVKKYS-DALNALHNLVSVDHKATFDYTLLHVTPPMGPLDVFKG-SPIAD--SAGWVTVNQATMQHVNPDFSNIFALGDCSSLPTSKTAAAITAQAPVLTENLLSLVDTAQYDGYTSCPLLTGYGELMLAEFRPKETFDQSKSNYHLKKLFPSAYWNFMV-K-GRWFGT Lenti61 RRKLSDLIPVKTFDPKASSVTTSSGKVGYETLVVATGLQINWSSIPGLETALGVSSIYSIDALHG-KAIFTQPAGVIKCAGAPQKIMWMAWDRYQKTGFYTGMPMFSVKKYS-DALNELHNLVGVNRKATFDYTFLHVSPPMGPLDVIKN-SPIAD--QAGWVSVDQGTLRHTNPEYGNVWALGDCSSLPTSKTAAAITAQTPVLTENLFSVVDTATYNGYTSCPLLTGYGQLMLAEFKPEESFDQSIPRYYLKKFFPWVYWKYMV-K-GEWYGA Malgl1 RRNEDSLVNVTTISPEQSQLTTASGKLDYEHLVIASGYTVTLDGIKGLREALSVCSIYTIDKLKG-QAIFTQPGSPIKCAGAPQKIMWLALDKWTKAGFATGMPMFSVPHYS-KVLDGLHNLVAIEKTAVFPFDFLHVTPTMSPPEFLRK-SPLAN--GAGYAEVDQAKLQHVK--YSNVWSLGDSSSLATSKTAAAITGQSPVLVANLLSALEGATYNGYTSCPLLTEYGKVLLAEFKLNETFDQSKPQYYLKKFFPWVYYRNMV-K-GTWAGP Mellp23 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele RRRQKQCIPIEGFDPEENSVSLHGAKITYDYLIVALGLEIRFDKVNGLTETLGVCSNYGLSAVKG-DLLFTFPNGPIKCAGAPQKIMYLADAHLRKAGYHTALPIFGVPKYA-SVLSSLSNLVEVDKEAVFTFDMLHVGPPCAPLPVYAT-SPLAD--SAGWVDVNKHTLQHNK--YENVFAIGDCNSCPTGKTAAKVAAESGVLYENIQKLMKGGSYNGYTSCPLTVGDNKLVLAEFGILETFNQANPMYFLKKVMPPLYWHGLI-K-GTWRGP Monbr VRRTSDVMPAATFAPEANSLTTAKGTITYDYLVLAAGFQINWDAIKGLKDALGVTSNYHMNEFAG-HAVFTQPNMPIKCAGAPQKVMYIFEDTMRRNGFMQGMPIFAIQKYA-KALTEQHVLTEVKKEAVFKYDFLHVTPQMGAPDCIRN-SPLAA--ENGMANVDKETMQHLT--FPNVFAIGDCANLPTSKTAAAVAAEAPVVKANMEAVMRQAKYDGYASCPLVISRDRLILAEFSPMETLDQSIPRFFLKAVMPDLYWDALL-K-GHWNGP Morel2 KMAMSEVMPVASFNPTKNTVVLANGSISYDYLVVAAGIQTNWGKIKNLPETLGVTSNYSIKAFKG-NALFTMPSTPIKCAGAPQKIMYLAEEQWRKAGYFTGLGIFAIDKYA-NELLKITDLAEIRKEAVFPYDFLHVTPPMGAPDFIRA-SPLSN--ADGWVDVNKETLRHNK--FDNVYALGDCSSLPTSKTAAAITAQSAVLKSNLLGDIFGAKYDGYTSCPLVTGSDKLILAEFSPQETFDQSKERYFLTKIIPDIYWKAMV-K-GNWDGP Mucci2 VKPMGDVMPVTEFDPENNTVKLADGTVGYDYLVVAAGIQINWDGVKGLKEALGVTSNYDIQEFKG-NALFTFPNTPLKCPGAPTKITFLAEEAFRLSGYNTSAGIFGVDHYG-RVLQQLHELIEINHQATFEYDFIHVAPPQGPPKFIKE-SRLAD--ASGFVDVNKDTLRHNK--YKNVFALGDCSNLPTSKTAAAITGESGVLKKNLIADIQGAVYDGYTSCPLIVGRDELILAEFSPLETFDQRKISQYLNKVIPAIYWNFLL-K-GTWTGP Mydma YKPMANFIPVLQILPEENLVVTGSDQLKYEILVVAVGLQLDFHKIQGLPESLGVGCNYSLQNFKG-NAFFTVPATPVKCLGAPQKIMYLADELMRKNGFKTPGPLFAVEKYR-NALLKIRNLVQIDKKATFDYSFIHVTPPMGPVDFIKS-SSIVD--STGFVNVNKNTLQHVK--YNNIFALGDCSNLPTSKTAAAVAAQSEVVRKNIRSLVKGSVYTGYTSCPLVTSSKTCILAEFDPRETFDQSKERYIMKAAMPFLYWNSLI-K-GTWGGP Neucr2 RRDEASLIDVSQLSPETDSVTLANGKIGYEHLVVVPGIEITYDKIKGLPEALPVSTIYGIEKLKG-QAIFTQPAGVIKCAGAPQKAMWLALDHWKRAGFATALPMFGVPKYS-ARLEELHDLVEVNNKAVFEFDLLHVVPKMGPYAFVKN-SAVAD--AAGFVDVNQATTQSNK--FKNVWSAGDASSLPTSKTAAAITAEAPVLVGNLLRSLEGLEYDGYTSCPLVTEYGKVMLAEFKPKETFDQGTPRYHLKKFFPWVYFNAMV-K-GTWGGP Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RKPLNTLIDVGAFAPTENALTLENGKINYEHLVVVPGINLNFGAIKGLSEALTVSTIYSIENFHG-NAIFTQPAGVIKCAGAPQKIMWLALDHWKRAGFATGLPMFGVPKYS-AVLEQMHDLLAIDKAAIFQFDLLHVTPKMGAHAFVKN-SALAN--EAGYVDVDDNTTRHKK--FPNVWSAGDASSLPTSKTAAAVTSEAPVLVRNLLQSMEGASYDGYTSCPLLTEYGKVLLAEFKPKETFDQAEPRYHLKKFFPWVYFNYML-K-GNWAGP Phybl2 VKPMASVMPVTKLDPDHNQVTLSNGTIGYEYLVVAAGIQINWEQIKGLKEALGVTSNYSIKEFKG-NAVFTFPNTPLKCPGAPTKIVFLAEEAFRLSGYNTSLGIFGIDHYG-KVLQKLNELISIDHEAVFHYDFLHVAPPQGPPNFIKE-SKLAD--SVGWVDVNKDTLRHNR--YKNVFSLGDCSSLPTSKTAASITAESGVLKHNLIADIKGAVYDGYTSCPLIVGRKELILAEFSPLETFDQRKITQFLNKVIPAIYWNALL-D-GNWVGP Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 RKPLNSLIPVQSFSPASNSLTTASGTLTYDALVVAAGLQINWTAVPGLASALGVSSIYSIDALRG-KAVFTQPAGVIKCAGAPQKIMWMAWDRYQKTAFYTGLPMFGVKKYS-DALNTLHNLIGVDRRATFDYTLLHATPPMGPLDFIKD-SPIAD--AAGWVAVDQGTLQHVNPEYANVFSLGDCSSLPTSKTAAAVTAEAPVLTENLFSVLDTARYGGYTSCPLLTGYGELLLAEFKPDESFDQATPRYHLKKFFPLVYWNRMV-K-GTWYGR Polpo QRNEKDLIPVATFKPDENLVVTKQGTLNYDYLIVATGITMYWDRIRGLKETLGVTSNYSIKGLKG-TAIFTFPNTPIKCGGAPQKILWLADSYFRDHNFNTAGVMFAVKKYS-DALDQMYNLIEVNKEAVFQFDMLHVVPPMGPIPEVKS-SPLADP-TTGYVTVNKETLQHTK--YPNVFALGDCSNLPTSKTAAAITKQAPCLVANLISHKNGAKYDGYTSCPITTSYKEIMLAEFKVAESFDQSKPSMLLKKVFPTAYWHGVL-N-GRWFGP Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 RRPMASLIPVQSFSPKSNAITTTSGTISYESLVVATGLQSNWDAIPGLSKGLGVSSIYSIDALRG-TAVFTQPAGIIKCAGAPQKIMWMAWDRYRQTEFYTGMPMFSVKKYS-DALDKLHNLTSIDRRATFDYTLLHVVPPMGPLNVMKG-QPIAD--AAGWVDVNKETLQHTNPEFSNVWAIGDCTSLPTSKTAAAITAQAPILTENLFSFVNTAKYDGYTSCPLLTGYGQLMLAEFKPKETFDQTVPQYHLKKFFPWVYFNAML-Q-GRWYGS Rhior3 VKPMAQVMPVTSFDPDNNTVKLSDGTVGYDYLVVAAGIQINWDNIKGLKEALGVTSNYDLQEFKG-NALFTFPTTPLKCPGAPTKITFLAEEIFRLNGYNHGGAIFGVDYYG-LTLQKLHELVEINHQAVFEYDFIHVAPPQGPPKFIKE-SKLAD--AAGWVDVNKDTLRHNK--YKNVFALGDCSSLPTSKTAAAITGESGVVKHNLIADLQGAAYDGYTSCPLIVGRDELILAEFSPLETFDQRTISQFLNKVIPLIYWNGLL-P-GTWVGP Rhoto1 HKPMNEVIPVETFQPDQNQVTTSDDKIKYDFLVVAPGLKIDFDAVKGLREGLPVSSIYSIQGFKG-RAIFTQPAGIIKCAGAPQKILWMAESQWRKDGFATGTPMFGVPKYS-AALEKIHNLVEIDKVATFEFGFLHVVPPQRAPDFVKS-SPLAD--AAGWVSVDPATTQHTK--FSNIFSLGDASSMPNSKTAAAITAQAPVLVDNLRAAHDGAKYDGYASCPLLTGHDELMLAEFKPKETFSQDVPNYHLKKFFPRVYWSALV-K-GVWFGT Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro MRDQASVMPAVAFKPEENKVVTQNGEFTYDFLVVAAGFQLDWDKIKGLKDALGVTSNYSMQAFKG-NAIFTQPDCPIKCAGAPQKIMYLFEDYITRQGFMQGLPIFGIKKYA-DVLTNISVLKEIKKEAVFNYDYIHVTPYMSAPDFIKK-SSLAN--AAGFVDVDQYTMQHVK--YPNIFSLGDCSSVPTSKTAAAVASESGVVKQNLLAALEGAKYDGYASCPLVTGRGKLVLAEFSPLETFDQGKERYSMKKLIPRMYWDQLI-T-GLWNGP Schco3 RKPLASLIPVQSFAPEKSSVTTSSGTLSYDTLVVATGLQINWDGINGLSDALGVSSIYSIEAFRG-KAVFTQPAGVVKCAGAPQKIMWMAWDRFRRTNFYTGMPMFSVPKYS-ERLNELHNLVSVDRRATFDYTTLHATPPMGPPAVIKG-SPLAD--AAGWVSVNQATLQHTNPAYSNVFAIGDCSSLPTSKTAAAIIAQAPVLTENLFSLVDTAAYDGYTSCPLLTGYGELLLAEFKPKETFDQATPRYHFKKLFPYAYWKYMV-R-GKWYGT Schpo1 RRELASLVPVKSLHPRENKIVTQSGEISYDYLVMAAGIYTDFGRIKGLTEALPVVTIYSIEKTKG-NAIFTQPSGVLKCAGAPQKIMWMAEDYWRRHKFYTGMPLFSVKRYS-DAL--LDELVEVKRKAVFPFDLLHAVPSMRSHEFIAK-SDLAD--KSGFVAVDQSTTQSTK--FPNVFAIGDCSGLPTSKTYAAITAQAPVMVHNLWSFVNGASYNGYTSCPLLTGYGKLILAEFLPKESFDQTVPRYHLKKFFPFVYWNFAV-RNGKWYGS Sorma RRDEASLINVSQLSPETDSVTLANGKIGYEHLIVVPGIEITYDKIKGLPEALPVSTIYGIEKLKG-QAIFTQPAGVVKCAGAPQKVMWMALDHWKKAGFATALPMFGVPKYA-ARLEELHDLVEVNTKAIFDFDLLHVVPKMGPYGFVKN-SAVAD--SAGFVDVNQATTQSNK--FKNVWSAGDASSLPTSKTAAAVTAQAPVLVENLLRSLEGAEYDGYTSCPLVTEYGKVMLAEFKPKETFDQGTPRYYLKKFFPWVYYNAMV-K-GTWAGP Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 EKPMSELVPVTKIDP-ENKVVLTDGEIKYDFLVVASGINVDWDKIPGLQETLGVTSNYSIRAFKG-NAIFTQPATPIKCAGAPQKIAYLAEEIFRQNGFHTGMGIFAIDKYA-AELTKVSNLAEIRKEAVFKYDLLHVTPPMSAPKFIKE-SGLAN--ADGWVDVNKETTQHNK--YSNIFALGDSSSLPTSKTAAAAAAQSAVTSHNLLSTIKASTYGGYTSCPLITGRGKLILAEFSPQETFNQGKESYYLTSVIPAIYWHGMV-K-GHWTGP Sporo1 HKPVSEVIPVKTFEPEQNQVTTSEGVISYDFLVVAPGLKIDFDQIKGLNEGLPVSSIYSIQNFKG-NAIFTQPAGIIKCAGAPQKILWMAESQWKKDGFATGTPMFGVPKYS-AALEKIHNLVSIDRIATFEFDFLHVVPPQTAPDFIKN-SPLAD--AAGWVAVDPATTQSTK--FANIFSLGDASSMPNSKTAAAISSQAPVLVDNLRAAMDGAQYDGYASCPLLTGHNELMLAEFKPKETFSQDKPSYYLKKFFPWVYWNSFV-K-GTWFGP Stehi1 RRPVSSLIPVQSFDPTSNSITTSSGTLSYDSLIVAPGLQSNFDQIEGLSKALGVSSIYSIDALRG-RAIFTQPQGIIKCAGAPQKIMWMAWDRYRRTGFRTGMPMFSVKKYS-DALNDLHNLVSVDRKATFDYTFLHAVPPMGPINVLKG-SPIAD--AAGWVDVNAGTLQHNKPEFSNVWSLGDASSLPTSKTAAAIASQAPVLVENLFQFMDTARYDGYTSCPLLTGYGQLMLAEFKPSETFDQKQPQYHMKKFFPWVYYQYFL-K-GQWFGP Tapde11 NIPMSEAIPVSKLNPEESTLTTDDGTHAYKSLILCPGIRLNYAAVEGLKETMGVASIYDVKGLEG-TALFTLPKGDIKCAGAPSKAMWMAEDYWRKSGFCTALPMFGVQRYS-DVLKQMTVLTKVNQIAEFKFDFLHATIPMAPHDFIKD-SAVSN--QAGHVAVDDKTLRSTK--FENVWSLGDASSLPTSKTAAAVMSQTPILAHNFYNANHGALYDGYTSCPLLVGYGKLVLAEFGIKESFDQSKPSYHLKKIFPQAYFSLFT-K-GHWYGR Thetr EQVTRTVAPVQSIDTENKVVRTKAGEISYDDLVVSLGVEY-YDAVPGLNDAA-------GALLRG-TVVVAVGSLPYKCPPLPYEAAFAVDAVLREAGVTTPMA--AVPPFAPHVFQDMAQPSAVDKTVTFEYTLLAATLPQRAPAVVREAMPIDD--PRGFVVVDPKSLRTS---VPHVYVIGDSATVKVNFAKAGLKVQPKAGKFAMVQAKTA----------------QAVLADARAGEST-----------------WDAPV-V-ATW--- Treme1 RRSLSALLPATAFEPTANRVVLADGKVEYDYLVVAAGLAINYDKIKNLTEALKISTIYSIKSFDG-EAVFTQPFGPVKCAGAPQKIAYMADAYWKTTPFITGMPMFAVPHYS-KILDRLTNLVEVRKTAVFEFGMLHVVPPMGPLGWIKK-SPLAD--SVGWVDVDQGSLQHKK--YPNVFSLGDASSLPTSKTAAAITAQAPVLTHNLVTLMKTAIYDGYTSCPLFISRGELLLAEFKRKETFDQSVPNYHLTKIIPHFYFSRMT-K-GEWYGP Trire2 RRPLNSLVDVAGFSPEDNSITLSNGKVSYEQLVVVPGISVNYGSVKGLPEALLVSSIYNIQRLHG-TAIFTQPAGPIKCAGAPQKILWLALDHWKRAGFATGMPMFGVPKYN-AALEQLHDLVAIDDKATFQFDLLHVVPKMGPHAFVKN-SGLAN--EAGYVDVDDGTTRHKK--YPNVWSAGDASSLPTSKTAAAITSQSPVLVRNLLQAMEGATYDGYASCPLLTEYGKVLLAEFKPKETFDQAVPRYYLKKFFPWVYYNHMV-K-GTWGGP Umbra1 ERPMGELISVTKVNAEENTVTLADGRIGYDYLVVAAGIQVNWDNIKGLKNALGVTSNYSIQDFKG-NAIFTFPATPPKCPGAPTKITFLAEEAFRNLGYNHAGAIFGVDHYG-KVLQRLHELIEIKKEAIFNYDMIHVAPPCGPPAFIKE-SNIGD--AAGWVDVNKETTRHNK--YSNIFALGDCSSLPTSKTAAAITAESGVLKHNLIADLEGAKYDGYTSCPLIVGRKQLILAEFSPMETFDQRQISQFLNKVIPEIYWRELL-A-GRWTGP Ustma22 RRPLASLLDVDTFAPEQNQITLANGKIAYDQLVVVPGLSINYDAIKGLPEALLVSTIYGIAKLKG-KAIFTQPAGVIKCAGAPQKAMWLALDHWKKGGFATGMPMFGVPKYS-ERLNELHDLVAIENTAVFQFDLLHVTPKMGPLTVIKN-SALAD--GAGFVDVDQETTRHKR--FDNVWSIGDASSLPTSKTAAAITAEAPVLVRNLGQAIQGAAYDGYTSCPLLTEYGKVMLAEFKPKETFDQGVPRYHLKKFFPWIYYNSYV-K-GTWAGP Walse1 VRPESSIIPVQSFSPASNTVTTATGTLTYDFLIVVAGLKINFAGIKGLEGALGVSSIYNIEAFKG-KAIFTQPAGVIKCAGAPQKVMWMANSQWNRSGFATGTPMFAVPKYS-QALEKLSNLTEIDKIAKFEYNLLHVVPPQGPLDFYKN-SPLAD--ESGFVSVDKSTTQHTK--YNNVFSIGDCSSLPNSKTAAAITAQSPVLVHNLRNEMEGAAYDGYASCPLLTGHGELLLAEFKPKETFSQDKPNYHLKKIFPPVYWNYFV-K-GNWFGT Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2271.fasta_al_trimmed; alignment length = 171] Allma1 ------------------------------------------------------------------------------------------------------------------KVPD-SLRFHTIEVFIDILEATTLLMPFIVMMAE-NVFERIRTILGILNTRDVN--- Ashgo11 PFVRQLASNSRSVREQALESLLQFDQLWKGLYFAMWFSDRPRPQQRLAAQLG-ELSLLFFSKAFWKVMCLEWYN-IDHHRLDKYLLLVRRVLYNQLR-FLWDAALVERYVAKVLKVYN-GIPFHIIDIFVDEWERLRFVAVFQGLAANIALREKIKQ-----DLLADQRLY Aspfu1 PFVKELASSDRRTRDKATESLLDLLKLWKGLFFCFYHSDRPLTQQALARNLSYTLVPTLFLRAFWITIGRDFHS-LDRLRLDKYLYLIRCYVGVAFE-IFWAE--LESYMT-IIHGPD-GLRYHLLDIWIDEIEKVLLLRPIEKLRKE-SV-----------ETLNDDRLV Aurde31 -----MSSAEKKTRDKAVKAVAEMDKLWKALFFCYWMSDKPLVQQALSSELA-ELLLTIFLRSFWETTVREWSG-LDRFRMDKFYMLVRKYVNAAFR-LLWDDAACKEYNS-MLKVPS-SLAYHLSDIWLEELEKAVLLEPFISLAAL-TTHERVVNAIALLETRDSNRRK Batde5 GFGKLLAHSDKRIRDKAVKSLLDMLKLWKGLYCCFWMSDKPLVQQSLAQDLA-QAATKLYICCFWKILIKEWYN-IDRLRL-------------------WDKDIIDKVMI-ILSVPN-SLQYHTSKAFFEELIKARLIAPCFGVLER-SYFKHVIDLLERLNILKNNKKE Botbo1 PLGKHLASSDKKIRDKAVEQLPEMRKLWKALFYCFWMSDKPLVQQALASDLA-NLLLEIFLRGFWEALVREWSG-LDRLRLDKYYMLVRRFTNASFR-LLWEESACREYQD-IIRIPS-SLAYHLSDIYLEELDKASLVSPFLTLAAR-TTYTRIQSVLRSVDARPANRKK Botci1 KLIKELAANDKKTRDAALLSLLDYLKIHSGLFYSMWMCDRPLPQQSLANSLA-SLL---FYTGFWEIMSKEWER-IDVLRMEKFLLLVRRYLAAGFE-VVVISESGEQVLE-VLRTPN-GMRFHVIDIWIDELEKLKLLEPLRKLGKE-SVRNKCK------EALGDERL- Caeel VFAQKLACGEPATRQRALRVLADLMRLCKGLHYVMWMQDKMILQEELADRIG-GLINIFFVACFLKSLSKEWPH-IDRWRMDKFLMEVRRMVRACFT-HLWKKDIRDEYWK-VF-----ALKFHFASILLDELDAAACLKPYIELLGN-KLFTSLYELTRHDNSFKQERKS Canalb1 SFVKKLASNDKPTRDSALESLLDLKKIWKGLYFSMWYCDRSKAQERLAENLG-KLY---FVLAFFDIISIEWPN-IDQWRVDKYYLLIRRILRHNFK-FLWDEELVENWVN-VLNVSM-GLPYHLCDIFIDELELVKLLEPFQKLNKS-ALREKCAE-----EVLNDERLK Cangl KFVKQLASNNRVVREKALETLVQFDKLWKGLYYAMWFCDRPRPQQRLASTLG-ALHVRFFSKAFWRIMCLEWLG-IDRFRLDKYLLLIRRALFNQFK-YLWHAPLVAKYLERVLKVYN-GIPIHVMDIMLDEWERLQVLDILRNLLKNYDLRDKIKK-----EVLTDKRLA Capow ASGKKSAAQESFARNLAVSDAMELLKLWKGLFFLMWHSDKPAVQEQTAERIA-TLVQSFFVDTFFETIMREWGG-IDKLRLDKYYVLVRFVVRQILE-ACWNQDVMEAVAN-VLVMCD-GLTMHLADVFFGELATALLLNPFSRLLAF-SVLSRLQDVAHQLTVKSENRQL Catan2 NLGKRLAAIEKKDRDTAFAALLDLLKLCKALYYSFWLSDKPLVQQELAENTA-AAI---YIHAFWQIIIAEWPS-LDKHRINKYYYLFRQLHKSTFA-VLWSEDVLDVFMS-MMRIPD-SIRYHTIEVYMDMLEQTTLMMPFVFMLGE-SIHERIQEIVSLMETPVGNRKR Cioin KFAQRLASNEKKIRDRAFKKLNEMIKMWKGLFYCMWMSDKPLIQEELANQMA-QLITQLYLETFLATIQREWLG-IDRLRMDKFLLLTRFMLRNAFE-CLWETGDIGWLTS-ILSGPSLGIRYHFIDIYLEELTACDLLLPFCSLVNN-TLKERVAEIIQNFDSDDLPQWK CocheC53 PFIRNLASSDKKVRDQALDALLDLLKLWKGLFYCLWMQDKPALQQRLSRDLA-SLVSTLFIRAFFLTMSREWSH-IEALRLDKYLYLIRQYVNASF--AFWKKSLLEQWNV-IMRIPN-GLRYHIMDVWVDELENVKLLQPIESMAKN-GL-----------ECLADERLR Coere1 ALGRRLAHVDKSVRDRAVAAIMELLRHWKALFYCFWLSDKPLVQQELSLSLA-SLTLACFARAFWETLCREWFD-VDKHRVDKYLLLARRMVFYGFQ-SMWDERVVESFLG-AYRIPN-SIRSHMADVYVDELVRLVLLEPFMRLIGT-TMPAIVQEEKRAGPTSKKNKRK Conco1 ---------EKTVRDSAIIATNQVTILWAGLFYGFWMADKPIVQQDTAKNIG-DVITLIFIEAFWSVLNSKWHE-IDRIRTDKFYLLMREIIHASFQ-LLWDIKNVKKMMD-IYHIPA-GIPSHVISCFHDELSKI--------------------------D-------- Conpu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci PLGKVLASTDKKTRDKAIKNLPDMDKLWKGIFYCFWMSDKPLVQQGLASELA-ELLLTIFLRGFWETIVREWNG-IDRLRIDKYYMLVRRFVNASFR-LLWDKSIIEQYTE-ILKVPT-SLSYHLADIYLEELEKVLILEPFFTLSAQ-TTFKRVESLRRALETRDSSRRQ Croqu1 PLGKFLASNDKVTRDRAVAALLAMAKLFKGLFYCYWMSDKPLVQQQLANELA-DLCLVYLWRGFWEAIRREWHG-LDRHRIDKYLLLLRRYTERGLR-LLWHPSAIAEWAQ-ILQTPM-SLAYHFCDVFLEEVNRTLLLDPFCHALAQ-AILQRIIELLRTLDCLEANRKK CryneH991 PLGKQLAHTDKKVRDKAVASLKEMAKLWKGLFYCFWMSDKPLVQQGLAAELA-ELLLKIFLEGFWDSVVREWAG-IDRLRMDKYYLLMRRYVNATFR-LLWEKEAIEAVNR-ILRVPT-SISTHLSDIYLDELNKVAVLQPHITLLAR-TIHTRIMSVLKAMKSTEPNRRK Crypa2 PFIRNMASSDRKAREQALASLLDILKLWKGLFYALWMCDRPLPQQQLCRDLA-ELV---WLRGFWATMAREWTTGIDVLRMEKFLLLVRRVLGVSLV-WAWDTDKVEQVLR-LLMVPV-GLKLHAVDIWVDEAEKARINDLVETLRKE-TVRIRSK------DSLADDRL- Debha1 GFVKKLAANDRKIRDAAFESLLEMEKLWKGLYYSMWLCDRPRPQERLAESLA-QLY---FTEAFWVIMIREWPN-VDQWRVDKFYLLIRRILRHNFK-RLWSSKAVDSFLS-VYSVSV-ALPYHICDIYLDELELVKLITPFQKLSKE-CLREKCKE-----EVLNDERLK Dekbr2 AFVRKLASNDRRTRERAFKVLLELEKLWKGLFYTMWFSDRPLPQKRLATKMS-QLF---FVSAFWYIMSQEWSK-VDKWRVDKYLLLMRYVVKECFE-MLFEEKLLCRYLS-ALKYAG-VIVFHIVDVWLDEIEEVKLLEPMVNLYNK-ALKKRIIE-----NVFEDERLE Dicdi ELAQKLNTGSSQTKSSALYKLIQLLKIWKGLFLSLYNTDKPIVQEEFSRDIS-KLTTYFFIKCFFIILQKHWDY-IDKYRVDKFYSLVRKMLNSSFQ-ILLNEQIYSGLVK-IF-NTN-GVLLHFADIYLEELFKVKILLPFVNFLTK-SSCKRIKEMFSKLDTLEQNRKT Dmel KIIRALACNDVVERNRQIRILDDFMRIWKGLYYTMWMSDKPLVQEELAEKLA-QMVDSFYFSAFMRTMCQEYFG-IDQWRMDKFLMLTRRMVRYLLR-FLWNADLIAAFNS-SM-----GMTMHYLDVFFEELAKAMFLRPFVTYIAT-QLVAQCRTLLQSIKALPPELQK Enthi SIGKIIAQKEPSIRDAGWKEA--MKEIWIGLYFWYWHSDGRDYQEKVRKEIT-SIMNKEFVKVGMETLERYWDE-IDYVRIKKYEMLLCQMIQKYLY-FIWNIEMIKEWNEYLL-----SFSTKVADYYYDYLNDVRLLIKYLKNGKIQSARERLQTKVEKLRAIKQEKRD Falba ------------IRDKGVADLLQLLKLWKALYYSMWMADMPPVQHLLGDSIA-DLV---FIVAFWQTIAREWHT-LDKYRLDKFLALIRKMVRASLK-SLWPEAEVVAHGT-TL-MPN-SVRFHLLDVWADELEVVRLMDPFLKAICR-VVFTHLRMLLDALTSRVSNRRH Fomme1 PLGKYLASTDKKTRDKAVKSLSEMAKLWKGIFYCYWMSDKPRVQQALSTELA-EIVLSIFLRGFWEAIVREWSG-IDRLRMDKYYMLVRKFVNAGFR-LLWEKEAVTEYKD-ILRIPA-SLSYHLADIYLVELDKVPLLYPFFDLAAR-TTYQRVHDLLRKMDTRESNRKK Fusgr1 PFIRNLASSDRKLRTASLETLIDAQKLWKGLFYALWMTDRPLPQQRLATDLA-NLL---WLRAFWTVLGLQWTG-IDVLRLEKFLLLVRRVFASHVR-F------VEAIVG-ILKNPV-GIRLHALDIWVDELERESLGDVVIALKRC-PVRARAG------DSYEDERL- Galma1 PLGKYLASTEKKTRDKAIKSLPEMDKLWKGIFYCFWMSDKPLVQQALASELA-ELVLTIFLRGFWETTVREWNG-IDRLRIDKYYMLIRRFVNATFR-LLWNKDTCLEYNQ-ILRVPA-SLSYHIADIYIEELDKAILFEPFIVLAAR-TTYKRIQSLLRRIETRDSSRRK Ganpr1 GFGKELASTEKKIRDKAVTKLDELARLWKGLFYCFWMSDKRPVQHQLAETLA-SIALRLYIGQFWRTLVAEWSG-VDRLRIDKFYLLCRRFHRAAFR-VLWSGEAVDAMCA-VLRVPD-SLRYHTAEVFFDEL-------------------------------------- Gloin1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 PFIRELASSG------------------------FYHSDRPLTQQSLARSLSFTLVPSLFLRAFWITMSRDFHS-LDRLRLDKYLYLIRCYVGVAFE-VFWKE--LGIYLD-MLKGPD-GLRYHLLDIWLDEIEKVLLLRPIVRLQEK-SV-----------VVLDDERLV Klula1 -LVKQLAGHRKETREQAFESLSQFDKLWKGLYYSMWHCDKPIPQQSLAYSLG-ELHLLYFSKAFWKVICIEWYR-IDHHRLDKFLLLIRRCLHFQIK-YLWEQALVDDYINKVLKVYN-GIPFHIIDILLDEWVKVDFISIFQELSSDTNLRDKIKE-----DLLKDQRLR Lacbi2 PLAKSLASTDKKTRDKAIKNLPDMDKLWKGIFYCFWMSDKPLVQQALASELA-EIVLTIFLRGFWEATVREWNG-IDRLRIDKYYMLVRRFVNATFR-LLWDQTSCDEYND-ILKVPA-SLAYHLADIYVEELDKVTLIDPFIMFSAR-TTYDRINSLLRRVETRDSNRRK Lenti61 PMGKYLASTDKKTRDKAIKNLSEMTKLWKGVFYCFWMSDKPLVQQALASEIA-DIILAIFLRGFWESTVKEWNT-IDRLRIDKYYMLIRRFVNASFR-LLWDPEACREYNS-ILRVPT-SLAYHLSDIYLEELDKAALLSPFFILAAR-TTYQRIQSLLKQMETRDANRRR Malgl1 PLGKYLASTEKRVRDRAIRSLTELSKLWKGIFYCFWMSDKPLVQQQLAQELS-ELVWMVFYEGFWHTMQSEWHG-VDKFRIDKYYMLMRRFLYSGLH-LLFDKVLLDRYIQ-IMSVPD-SITYHVCDTYLDELQHTDLLAPFMDLAAT-SMYDRVMSSWQRLNTYAPSRRK Mellp23 PLGKFLASNDKSTRDRAVAALLSMSKLYKGLFYCYWMSDKPLIQQQLANELS-DLCLVYFWKAFWVAIRAEWHG-IDRHRIDKYLLLCRRFLGVGLR-LLWNQKAIEEWSE-ILTNPM-SLAYHFCDIFLEELNKTSLLSPFLYALSN-SIFQKIIEVLKSIDCLEVNRKK Mnele SFAKRLAHNNKDTRNAALKKVDEIIKIWKGLHYSMWYSDKPLTQESLALDIS-QIVSLLFFGGFCETIAREWAG-IDRQRLDKFYMFIKTALKCVLE-FCWKEEIVKSVVD-TLQCPD-SISVFISEHLYSLYTEVELLSCYVTVLSK-TLSQVLMSSQYQLKTLSQSKNL Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 PFGKKLAANDKKTRDKAVKALIELMKLWKGLFYCVWMSDKPIIQQQLSETLS-SLILRVFIATFWETICGEWHG-IDRLRLDKFYFLLRRFLSYSFR-MLWDLETIEEFTT-VMQVPD-GIRFHLIEIYLEELEKVHILQPMFHLLGQ-T-------VFKKVEVFEE---- Mucci2 PLGKQLAANEKKTRDKAIRSLIELIKLWKGLFYCYWMSDKPLIQQALANDLG-ALVMEMFLKAFWQIHCQEWHG-LDRIRLDKYYLLLRRVIYFSFQ-FLWDQVYLEAYTD-MLKNPD-AIRYHVIDLYFEELEKVEI-------------------TLRNKEALKAHEME Mydma HFAKKLANNDKKIRDRAFVKLTELLKIWKGLFYCMWYSDKPLVQEELAANLA-NLIHIFFSKVFFVTIGREWIG-IDRLRLDKFYFLIKLFIHETLK-CLWNYQNVLQHSK-FLKFPD-SLKIYLTEKTLPELSVLLLVEPFLTAIAF-TVFKAVREVKQKLDTATKNSLQ Neucr2 PFIKNLASSDSKIRKSALASLIDILKLWKGLFYAMWMCDRAIPQQTLAQELA-DLI---WLRGFWATMSREWTS-IDVLRMEKFLLLVRRVVGASFR-W-WDAKRVDQVLD-ILKIPS-GLKIHVLDIWVDEAEKVRIIEKIEELEQR-TIRVRSK------DSLSDDRL- Orpsp11 ----------KKTRDNAVKKLLELLKLWKGLFYCYWMSDKQLIQQQLANQLG-ALILKIFLKAFWKIIIQEWNG-LDRLRIDKYYYLMRRIHYYTFK-FLWKKRYVTEYVN-LY--------------------------------------------------------- Pench1 PFVRELGSSDRKARDKALDSLVDLLKLWKGLFYCFYHSDRPLTQQALARALSYSLVPSLFLRAFWITIGRDYHS-LDRIRLDKYLMLIRFYVGVAFE-VLFPD--LAAYIS-IIHGPD-GLRYHLVDIWVDELEKVLILRPLEKLRAE-SV-----------EALEDERLV Phybl2 -------SLDKKTRDKAVRSLTDLLKLWKGLFYCFWMSDKPLVQQALANDLG-SLVLEMFLSAFWEVHCKEWYG-LDRLRLDKFYLLFRRVIFFSFK-FLWDEELVADYTN-MLTKPD-SIRYHIMDIYFGELVKV----------------------------------- Picst3 SFVKKLASNDRPTRDAALEALLDMEKLWKGLYFSMWFCDRPKAQERLAENLG-SLY---FVEAFWSIMIKEWPS-IDQWRIDKYYLLIRRVVRHNFQ-FMWDSEILQKWLD-VMSVPV-ALPYHLCDIWVEELERVELISPFTRLNKE-ALREKCKE-----DVLDDERLK Plicr1 PLGKYLASTDKKTRDKAIKNLTEMTKLWKGIFYCFWMSDKPLVQQALASELA-EIVLSIFLRGFWETTVREWNG-IDRLRMDKYYMLVRRFVNAAFR-LLWDSAVCDEYNA-ILRVPA-GLPYHLADIYLEELDKITILAPFLTLAAR-TTYKHIQSLLRKVDTRDANRRR Polpo EIAEGLVSEDPKTRLAHLTQLLELLQIWKALFTYVWGADKPLWQEKLNEKIS-DLIGIFFIRAFFVTMFQKWHL-IDRYRLDKYYSLVRKMLRKSFKFLL---ILLQDFID-VLAETN-GLVLHISDIYLVELYKVKLLMPFINYLAK-SAALRIRDMLSKLKTKAENRKL Pucgr2 PLGKFLASNDKLTRDRAVAALIELAKLYKGLFYCYWMSDKPIVQQHLAQELA-DLCLIIFWKQFWIALGSEWQG-VDKHRLDKYLMLMRRFVEVAFK-ILWHPKAIERWSE-ILKTPQ-SITYHVSDIFLEELNRVPLLAPLIHGLSQ-STFRKILELLSLLLCSDANRKK Punst1 PLAKYLASTDKKTRDRAIKQLAEMAKLWKGIFYCFWMSDKPLVQQALAAELA-EMLLTIFLRGFWDVIVREWSG-IDRLRMDKYYMLVRRFLNASFR-LLWNEPACAEYTQ-IMRIPQ-SLAYHVADIYIEELGKAILFSPFFEFAAR-TLYQRVQELLQLLEVRDANRRR Rhior3 ------------------------------------MSDKPLIQQALANDLG-SLVMELFLKAFWQIHCQEWHG-LDRIRLDKYYLLLRRVIYFSFQ-FLWDAVYLDAYND-MLTKPD-AIRYHIIDIYYEELEKVEI-------------------ILRNKEAIKEHELE Rhoto1 PLGKFLASSEKHVRDKAVQSLPEMDKLWKGIFFCYWMSDKPLVQQALADTLS-NLTLDVYLRGFWHAVTREWSG-IDRLRMDKFLLLMRRFVFVAFR-LLWDARAIQEYNE-MLKIPH-SLAYHLFDIYVDEIERLALLQPMYTTAAR-AMYSRLMEVLKGLETDETNRRR Rozal11 QFGKLLAHTDKKIRDQSFRKFLECMKVWKGLYYCYWMSDKPLVQQELASKFA-KFFLNA-LKCFWDTMMREWPG-IDKWRLNKYYNLFREVLQASIL-LLWDLVQVEKWKM-IM-----SIKLHIISKFLGCLRRSALLTPIMELIEQ-SVFEKIKDEKKYIKTKRKQRKI Sacce1 NFVKQLSSNNRKTRVNALEALIEFNKLWKGLYYAMWFSDRPRPQQRLANELG-ELHGLYFSRGFWKVMCFEWFN-IDRYRLDKYLLLIRRVLFSQLK-YLWDKKLVDEYIKKVLKVYT-GIPIHIVDILLDEWERLDVIAIFQDIVADYNLREKIKE-----DLFSDTRLV Salro ALYPLLTANELRTRNLGIRKAREMMKLCDGLFYTMWMCDKPVPQAQLAQLLA-DIMLDIYASCFYAVFEQKWGG-VDRWRMNKFYDLLSRLTKAVFQFSVEPGDVIQDVTA-MFQTSL-GPVMHLIGTFTPTLVAAEYLDLIVTLVKY-HLRGRLPGLCATLNIHVPRRRA Schco3 PLAKYLASTEKKTRDKAVKNLSEMDKLWKGLFYCFWMSDKPLVQQALASELA-ELVLTIFLRGFWDAMCREWAG-IDRLRLDKYYMLVRRFVNASFR-LLWSEEVCSEYNE-ILKIPS-SLGYHVCDVYLEELEKAILISPFLNLASR-TTYARVESLKKTIETRDPSRKR Schpo1 PFIKKLAANDRKTRDKALESLLDFLKLWKGLFYCMWMADKPLYQQKLSDNLA-ALVPIVFQSTFWETMGREWTG-IDILRTDKFYLLMRRFCAAAFR-DILLDKVVAEYNQ-MWAFPN-GILFHLADIWTEELRKVDWYLPFDSTIKS-S-------LPKRL--------- Sorma PFIKNLASSDSKIRKSALTSLIDILKLWKGLFYAMWMCDRAIPQQTLCQELA-DLI---WLRGFWATMSREWTS-IDVLRMEKFLLLVRRVVGASFR-W-WDAKRVDQILD-MLKIPA-GLKIHVLDIWVDEAEKVRIIEKIEELEKR-TIRVRSK------DSLSDERL- Sphar KFGRRLANSDKRLRDKAVNKLLESRKVWKGLYYCIYMSDKPLVQEELVSVVS-QLVHLIFIDAFFYIMISEWSR-IDRLRLDKFYMLVRECLLQFFV-WCFDMEIVKQFVE-LLTVPK-GLKWFVMEKFLVQLEKVMYLQPFYHLLAF-ETRAKVKEEENRIPSSEPHKRR Spipu1 GFGRQLAHTDKSIRDRAVRGLLDLLKLWKGLFYSFWMSDKPLIQQHLADKLA-SLALHLYIRAFWTIIVADWHG-IDRLRLDKYYMLLRKFHFYGFK-YLWDADVVGEYLQ-ILKTPD-SLRYHTAEVYLEELQRAQLLDPFFDIISK-SVFAKVREKKKKKDGIEQYKVE Sporo1 ----LRDPGEKPIRDKAVASLLEMAKLWKGIYYCFWMSDKPLVQQALAQTLA-DLTLVVFLKGFWSTVCREWVG-LDRLRIDKFYLLIRRFVEVGFK-FLWDPKAIELYNE-ALKTPH-SLVFHLSDIFLDELERVGLVQPYMHTLTV-AIFARLIDVLKSLEVDEHNRRK Stehi1 PLGKYLASTDKKTRDKAIKSLNDMTKLWKGVFYCFWMSDKPLVQQALASELA-EILLSVFLRGFWEMTVREWSG-IDRLRIDKYYMLIRRFVNASFR-LLWSSASCQEYND-ILRVPA-SLSYHISDIYLEELDKVTLFSPLFTLAAR-TTYQRIQSVLKAFETRDSNRRK Tapde11 PFLKQLVASDRKIRDAALASLLELLKLWKGLFYCFWHSDRTLVQQNLANDLS-NLVLTVFLNAFWITICREWNS-IDILRLDKFYTLLRRFIGTAFQ-KLWKESFVNEYIS-LLKVPN-GIRYHLADIYIEELSKAIFLRPFETIITK-SV------VMKSVKTLTEYGYE Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 PAGKFLVHTDKKIRDKAFKGLMEMTKLWKSLFYCFWMSDKPLVQQAFANDLA-ELLLLIFLNGFWEAIVREWHG-LDRLRIDKYLLLIRRYVNATFR-LLWSISSVEAVNS-ILKVPA-GLANHLADVYLEELDKVLILQPHITLLAR-TIHSRLMMILKAMHAVESNRRR Trire2 PFIKNLASSDRKLRVESLSSLLDARKLWTGLYYALWMTDRPRPQQALASDLA-NLV---WLAAFWSVLGTQWPH-IEALRLDKFLLLVRRVFAAQVR-V-----VVEGVKR-VLRVAL-GLRLHVLDVWVDELEREFVGGLVEGLKRC-PVRQRAG------ESHDDERL- Umbra1 PFGKQLAANEKKTRDKAVRSLKDLLKLWKGLFYCFWMSDKPLIQQSLSETLG-SLIMSLFLGAFWQIHCEEWHG-IDRIRLDKYYMLLRRVIFYTFK-YIWDLGIIDDYSE-LLKIPD-SIRFHLSDIYLGELEKVELLDAFINLLAK-TTAKKVTEIKKKKEVVEEEEEE Ustma22 PLGRALASTEKRIRDGAVRSLLELQKLWKGLFYCFWMSDKPLIQQRLANDLA-QLVLVHFLEAFWDTIVAEWSG-LDKHRIDKFYLLVRRFVAAGFR-LLWPSEAVKDFGR-ILRVPD-SLTYHLSDIYLDELEKVELLMPFVDALAT-AMYDRIWSIFQALDATEARRRL Walse1 PLGKYLASNEKRERDKAIRNLLESAKLWRGIFYCFWMSDKPLVQQKLAWDLS-NILLEIFYKGFWDELIREWSG-LDRYRLDKYYMLIRKFLQAAIK-VCFN--SLDTFNS-ILRVPA-SLTYHMSDIFTDELNKAQLLKPWSQLLAH-TAYKRVFEISNILSANPTNRRK Zygro1 AFVKQLGSNSKPIRDNALEKLMQYNKLWKGLYFAMWFSDRPRPQQRLANELA-ELHMLYFSRAFWKIMVMEWLQ-IDRYRLDKYLLLMRRVLYNQLK-YLWSSKLVDTYLEKVMKVSN-GIPIHIMDILLDEWQRLSFLAIFKELLSNVDLRNKIKR-----DFLRDERWG [Cluster2275.fasta_al_trimmed; alignment length = 140] Allma1 DYYDLDGILAEQQCLPATFQVHIPGMGYLDGTNEDILEGTKIPLPVWLIDTLNETDLPKALTEAVLRHLRASASKVNLQALYFMVAEKLQDTIAQAFQDRLKAVMDHTQ-EFVQGLDMVERDIKRGQDASLQVKRWAMRT Ashgo11 GYYDLDDILADSSKFACRFNYELPGLGYLEGNGKPVGKHSKVELPLWLASVLAEFLPPEMFSARVVNAIKADAPTLDVHSIFYALGTRWAGMLAGMVLERALEVQRHAAS-MLQTLDEWERQLRRAHAASRDAKLWAARR Aspfu1 -YYDVDSILTDSQKLPCTFELEVPGLGILEGNGEDIKAGTRIDLPLWLGVMLSTLDLPSALSDRVVNALKADPRTVDLRSLFYSLSERVLDVLINTFKKRAAEIADHAHNDFLRGLDETERQLRVAHDSARETRIWAGEA Aurde31 TYLDIDAIFAEQQKVSCLFEIDVPGLGYLDGGERDIKKGTKMQLPFWLAVPLLKFDIPPPFTPRVRHALNAEARSVRLSSLWYAHGRNITEVLSLTFKQRLMDLMDQAQHEFREGLDQTERELALAQESARRTKAWFDSS Batde5 DYWDLNTILAEQTKVRCHVKLPAYGYSFLAGADDSLLVNSIIDIPFWMGKPLADLEIPTCFSDAVQDELLASPVCVKISLHFFKFFADLLELVTKTFKSRLCLLSDYTMTAFVQTLDATERHLEAGLQSAEALSAWQRRD Botbo1 DYYSIDAILADNQKIQCTFKLDVPNLGYLEGGEKDIKTNSKIQLPHWLAPTLLDFAIPPPFSLRVRKALNAEPRHVRLSSLWYSFGRMIVKVLQQTFHARLVDLMDQAQNDFREGLEGVERELTLAQDSARATKLWYESS Botci1 ---------------------------------------------------------------------------------------------MESWRTRAGEISDHAGSEFLRGLDEAERGLKAAHEGSKAMGKWMGEV Caeel KFFDLDDIIAKSDSTSCTFE-----IGDLNPDFQEMLGVSKVDAPYWLLESVRSIQLPKAYSVNMQNVLNADSKKLNLSGLFYGNGMQLCRCLVSTLTQRLGEIVSTATH---EKFDSLETKVLEGKRCKEDIDTWLRQD Canalb1 DYYDLDDILADSEKLTCKFNITVPGLGYLEGNGKPIHEDTKLELPHWLSGILADLADPDIIKEKVINAIKTDPLAVDLHKLYYSLILKWGANVMNCLKARSLEIYNFSNN-FLYTLDEFERALKSTSDSNKSMRKWLKTK Cangl GYYDIDDILVDSTEVPCKFNYEIPGLGYLENNGKPIRKNTKLSLPLWLARVLAELLTPDMFSNKVINAIKTDPKSLDLHAIFLDMALKWIEIVYELLLERAQQINNYASSRFLLKLDEFERQLKDTHDSYRDTKKWVSK- Capow AYHDIDEILMEQELVPVAFKTEAKWLGHLDPGSPDLPEGARLDIPFWMVVNLHEVFAPKQYSQSRRNALIAEATSVNLNEWYYRLGLRLEQVLQQAFIDRYRNILDLSQHDATRRLDSLEKKLNAGHAAVAEFRMWKRNE Catan2 EYYDLDAILADQQSIPCTFKCKVPGLGYLQGSEEDILEGTKLNLPLWLAEGLLAPNLPKAFSEPILRQLDASAPSVDLHNLFFRFAEKFIVLLSEAFGDRLTSIMDHTQ-HFVQSLDMTERDIKQGQVASEQLKKWQMRE Cioin NYLSIDDIMMSSEKIPSTFLVSVKTLGYLDPSKKDIEVGSKLDLPLWLALSLATVELTKPYKATYREILKADAGVVNLYKLYYALGQQQLRSLILAFSDRFRRIMDLSGNSLIQQFDEVERRLALGQKSLQSFQRWEVGE CocheC53 -YYDVDAILTDAQKVPCTFELTVPGLGYLEGNNGDMKQGSKVELPLWLGEMLATIDPPSALSPRVLNALKADPRTVDLRALFYNLGARILEVLSDTFKARAALIADQAHNDFMRGLDENERQLRAAHDSAKGVRTWMTDL Coere1 GYYDIDDILAVQERVPCVLQVDLDGLGSAGGGTSKVYRNSRWTLPFWMADRLNDMEVSPIFSKRANRMYAASPESVQLRSIYYQFGLQMGHVLRNMYMQRIQKIARIAQQDFVQSLDRTEARLKLCQQAQGAIPEWQQNK Conco1 GYFDIDDFLVEDQLIPVIFTKELEGMGELNGSETKIEAHTKLELPLFTTKFLIDYEFPKCFNSKVQHALKACAQNIDLHSLFFYFALKCSNFINTTFIERLVYIYDHSQSNMVQTLDELELKINSSLEQVKEFEHWIRTT Conpu1 DYFSIDAILAENQKIQCTFKLDIPDMGHLGGGERDIKALSKAPIPIWLAYILLDFSIPQPFGARVRNALNAEPKSVKLSGLWYGFGKMIMELLIKAFKGRLVEVIDQAQHSFREGLDGAERELALAQESVKMTKRWYEGN Copci DYFSVEAILAENQKIQCTFKQEIPGMGHLAGGDRDIAVLSKVQLPMWLAYIVIDFNIPPPFGLKVRNALNAEATSVRLSNLWYGFGKMIMKMMTTAFKARITELVDQAQHLFRQGLDTTERELLLAQESAKRIKTWYEEN Croqu1 -YYSLDQLLAESQKIPCIFNVKIPNMGHLEGTQRDIQPHSPIELPYWLTSLLLSVQMPKAFDPRVRNALSASARSVNLRTLW--------VILFNTLKNRLEDIMDLAAREFVNGLDEWEKEIRVGQETTKKMKRWEASK CryneH991 DYFSITSILADNHKMSCTFALDVEGLGYLEGSENDIREGTKVELPFWLAQTLSTFALPLPYSSRVQSALVASPVSVKLSNLWYRWGKKLANMLLRAFTGRLPTLQDLAAH-FRDGMEGDERQLSIGQDSGRLFKAWYDRK Crypa2 -YYDIDAILTDAEKIPCEFNVSVLNLGHLNNNGEDLKAGTKLSLPLWLGEMLANLSLPDALSSECIQALKADPRAVQLRQRFYGLATRLMSVLRKTFVTRAAEIALHARKEFTRGLDQWERDLTKAHTGLKGGKEWMHNV Debha1 NYFDLDDILSDGEKIPCRFNITVPGLGYLEGNGKSIAKDTKIELPLWLAEILADLSQPDFINYKVINAIKTNAVNIDLHSIYYKLSEKWAEVVMQMLKERSFEINNYASN-FIFSLDEFEKKLKVTSDSNKQMRKWLKD- Dekbr2 -YYDIDDILADSQKLPCKFNFSIPGLGYLNGRGEPIKEDNKVELPLWLAEILARLIEPEFFSKQFLNFIKSDPLRINLSPYYYKIVSKWSDLISKMFVSRASEIN-----EFLNSLENSERDLKISHTSYKDIKNWFIEK Dicdi SYFDINDILAEEQKITCNFFYDAYNLGQLEEGDPDMKKGSKVDLPYWMALALASVIMPPEYQDEYKNKLIADPNVISMRLFYDKIGVQLSLLLFRVFRERFLNIYSQSINKILGNLTYQEREVSNGYKSSNDYDKWMSRK Dmel -------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----MEHLISEETKVTVQAIQDISGLGFLDKSDSSIPEGRKFQIPLWLAITLQNKEYSRQFIKKATDVFEVNPSSINFSKFYFEVGGNIAKSIRNMMLIRLRRIYDEA--KFVRTLTHSEKELQEIIDVNAQSKKVKTME Falba DYYDLDDILAEQERVTCQVRLR------LRSSGEPVDRKTKFEIPFWLAQGLETTNVPRAFGPRAGAALKADPVGADLRTVYFRLGQKIAEMLHEAYTSRLSHVLHTAHRTDLERLDACEREVRLAYWAASMSSHWRKSA Fomme1 DYYSIDAILAENQKVQCTFKVDVPDLGYLDGGDRDIKALSKLQLPFWLTPMLLDCTVPHAFNQRVRNALNADATSVKLSGLWYAFGRMIAEMLSTTFKQRLVNIMDQAHHDFREGLDGTERELALAQESAKLTKQWFESS Fusgr1 -YYDIDAILTDAEKVPCQFEIDVPYLGHLDNS-NGLKANTPLTLPLWLAEMLATLNLPPCLSTAVLSALKADPRAVPLRDHFYGVGVRMLEVLRKTFVVRAGDVGLHARKEFLRGLEEWERGLRRGHEGVKGAKEWTDKV Galma1 DYFSIEAILAENQKIQCTFKHEIPGMGHLGGGERDIALLSKVQIPIWLAYTIIEFNIPAPFGLRVRNALKANACSVRLSNLWYGFGKTIMDMLTKAFQERLVEVIDQAQHVFREGLDTTERELSLAQESAKRIKLWYEDS Ganpr1 EYWDIDAILAEQQKVACYVKSDVPHFGYLAGSSQQLPKGSRVEVPFWLASQLADIEVPRCFGTRARNDLKASPTAVDLNLLFYAFGCSIFKVLATTFTQRMQRVMDYTQSRFLRTLEEEEKELRLGVHSA-----LDTRR Gloin1 ---TVEEFFAGETKVPIKFDRNVLGLGNLIGKTKEILKDQVYEIPFYIAEELVTLQLPKIFGNDVMNALKVTPIDMNLRNYFYTFASDYAEILKRSKIDRAVEILNRAKRDFLERLDDDERKS----------------- Hisca1 --------MADGG-------------GVLAGWTRNYHAPSNSRFQGWVTWMAMTLDLPSALSEKVMNALKADPRTVDLRSLFYRLGVRILDVLMETFKKRAMEIADHAHNEFLRGLDETERQLRAAHSSAKEMRAWSGET Klula1 GYYDIDDILADGTRFPCRFNYDVPGLGYLEGNGRPISKNAKLELPLWMVHLLAELLPPDLFAPRVLNAIKSGATSLDLHSIFYTLAEKWAQVLKDMLLERGQEINNHAIS-FLQTLDEFEKTIRDTNVNCKEMKKWLVLK Lacbi2 DYFSVEAILADNQKVQCTFKHEIKNMGHLGGGERDIPVLSKMQLPIWLAYILIDFNIPAPYTTRVRNALKAEACSVRLSSLWYGFGKIILEMLTKTFKARLVEAIDQAQHSFREGLDTTERELALAQESAKRTKRWYDDS Lenti61 DYYSIESILAENQKIQCTFKTDVPDMGHLDGGTGDIKALSKVQLPLWMVYILIDFTIPPPFAARVRNALNAEAKSVRLSALWYGFGRMIMKVLTDTFHKRLPEVIDQAQHAFREGMDGTERELQLAQESAKRTKLWYEAS Malgl1 DYWGVDDILAESQHIPCVFHVDVPGLGYLEGSDDDIHKHSRLELPYWIAHMLA--------------------------------------------------------------------------------------- Mellp23 -YYSLDQLLAESQKIPCTFNVKIPNMGHLEGTQRDILPHSPLELPFWLTSLLLSVQMPKAFDSRVRNALSASAKSVNLRTLW--------KVLYKTLKDRLEEIIDLAAREFLNGLDEWEKEIKVGQESTKKMKLWEASK Mnele DYFSFDSILAEQQKIACVFKKSMFGLGFLDPSNENLVSGSKMELPLWMASYLAACELPKPYQETSRNILLADSSVVDLFKQFYETGTKLIVSLVKTFVGRFKKIMDSSQNNMCQKLDVEEKRLEINRLSVELLDKWERRE Monbr -------------------------------------------------------------------------------------------------------------------------------------------- Morel2 DYYDIDAILAEDQNVKCAFQSNIPGLAWLEGG--ALKAGSRFDIPFWLARELVDIETPEFFGPKVRNALRADANTVDLTKQFFRFGTVYLGVMEEAFKARLQMTMDHTQSDYLNRLDETERALKAGMESSASIHQWNQHS Mucci2 EYYSIDSILAEQQKIPCITLHDYSKEANLNGD--ELKRGSRVELPYWIAKPLASIELPKTYSTKVRNVLDASPTSVDFKLLFYLFGRKLLSVLEKAFKTRLRDVMDFSQSVYLQKLDETEKELRVGQESALQFIQWRDRS Mydma YYYDLDDIITMQEKVPVQFELPCYRLGFLDPSEEHLQQGTKMEVPCWLAFELCSVELPKIFTENFRQIYKADPNVLDLHKLFYNFGLKMLRTILEIFVKRFRQIMDNCQNKMKEKLDEMEIVLDNGQRALKDFTEWQIGN Neucr2 -YYDIDAILTDAEKIPCTFQIDVPDLGYLDNQGHTLKSGSRVALPIWLAEMLATFDLPPALGNDVVQALKADPRSVPLRDQFYALATHMMAVLRKTFVSRAAEIALHARKDFLRGLDEWERKLRSAHDGTKASKEWMENV Orpsp11 DYFDLDDILAEQQKMQVSFKEDIPGLGFLENNGEPLHKDEKVLLPFWIITELSELSNPKCFKNQFKNQLIAGPTSVQLYQAYFQFGYKLSLILETSYKLRIPLIMDYSQQEFIRGLDECERQ------------------ Pench1 -YYDIDSILTDAQKLPCTFELEVPGLGILEGNGEDIKAGTRIDLPLWLGEMLSTLDMPEALSERVMNALKADPRTLDLRALFYNLSERILDVLGDAFKKRAADIADHAHNDFLRGLDETERQLRVAHDRAKDMRIWTGEA Phybl2 EYYDIDSILAEHIKIPCTLNHDLGAKVNLSGH--EVKKATQLELPFWMAKPMAALEIPSFFGRRVRNNLNASPTNVDLQSAFYVFGTKLVPLMQKTYKARLREIMDHSQTEF----------MKSGLESANLLRQWQNRS Picst3 -------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 DYYSIDAILAENQKIQCTFKIDVPDMGHLGGGERDIKALSKIPIPLWLSYIILDFSVPTPFTNRVRNALKAEAKSVKLSQLWYGFGKTVMKVLTKAFRDRLIEVIDQAQHQFREGLDTTERELAMAQESSKRTKVWYEAT Polpo -------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 AYYSLDQLLAENQKIPCIFNIAVPGMGYLEGTERDIQPYTPIEIPFWLASILSTIQIPKAFNLQIRNALSASTKNVNLKNLWYESGMALLIVLHKTLFDRLPDIMDLASRELSVGSDSWEKEIWTGQLMTKKFTDWEKGR Punst1 DYYSVDAILAENQKIQLTFKVDVPDMGHLDGGERDIKPLSKVSIPLWLAYILIDFSIPPPFSSRVRNALNAEPKSVKLSGLWYGFGKMVMTILTKTFKDRLIEVIDQAQHSFREGLDGTERELALAQQSAKNAKRWYETT Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 SWYSVTDFLDDATKLPSKVLLDIPNAGHLEGGDKDLRAGTSLELPFWLASKLSDLTLPRAYSPMVRNALSASPESVHLRNLFYAGGMRLLTILDHSFKTRLVQIMDQSQHEFAQGLDLWEKELTVGETSAKQMKTWFDTK Rozal11 RYFDIDLFLAEDMKCQCVPEEELLSFMSL---EENVRNTAEVDIPLWLIETLQDFRLPKILGTKVQE---------DLKNL----------------------------------------------------------- Sacce1 GYYDIDDVLADGTEFPCKFQYDIPGLGYLENNGRPITKNTKLSLPLWLARILAELLPPDMFSTKVMNAIKTDPVALDLHSIFFSLAIKWINVVSELLLQRAQELNHHASS-FLLKLEEMEKEIKKSHESYKDTKRWMFKK Salro SYFDIDDILMQEERLPCVASIDVIKMGSLDPSTPYLRKGSKVDLPLWLIKSYREVDPPKFLGPKYLDMLRADATVINLQSWFFSFAITYLTTIQDSFGHRYLVILDISQNEKTRNLDQLERQLHAGLQDDRAQQQWRRRQ Schco3 DYFSIDAILAENQKIQCTFRRDIPDMGHLGGGTKDIKAGAKVAIPIWLAYVLIDFTIPTAFGPKVKNALSAEEKSVRLSGLWYSFGKTVMDMLTRTFHKRLLEIIDQAQHSFREGLDATERDLTIAQESAKRTKKWYEET Schpo1 -YYDIDSILSENQKVPCTSTVSIPGLGH----GRMVPTGSKVELPFWLAEVLASIHMPAPFSSVVRNALKANPNSVSIRDIYYHFAEKMLQISLNTLRSRAMLIADASLNQFIEGLDDFEKHIRVSHNAHRSLINWQNST Sorma -YYDIDAILTDAEKIPCTFQIDVADLGYLDNQGHTLKSGSRVALPIWLAEMLATFDLPPALGNDVVQALKANPRSVPLRDQFYALATHMMAVLRKTFVSRAAEIALHARKDFLRGLDEWERKLRSAHDGTKASKEWMENV Sphar -----------------------------------MKAGSKTELPYWLASMLCRIDVPKVYTPKYTAKLIAGPETVAMSDWYFLLARRYAPVLKETLLTRFRKII-----LLMRKLSDVERRLVKKELAVTDYEDWRKSS Spipu1 EYWDLDAILAEQQKLPSFFRMDVPGYGFLEG-DVDLAANTRIELPYWLAEHLADLELPKCFGHRVRNDLNASPTSVNLGSLYYRFGVKIIDILADAFIARLPLIMDYTQTEFIYSLDETEKELKTGHESVTAMAQWDQRK Sporo1 --------------------------------------------------------MPRPYNQTIRNALAASPEAVHLRNLFYAGGTRLLQTLEGAFKTRLVQIMDQSQHEFSQGLDTWEKEHELSETDEELAR--FERR Stehi1 DYYSIESILSENQKIQCTFKIDIEGMGHLAGGEKDIKQLTKMQLPLWMSCMIVDWHIPTPFSSRVRNALNAEAKSVRLSSLWYGFGRSLMRILTKAFHSRLVEVIDQAQHSFREGLDATEREMALAQESAKRTKRWYETS Tapde11 GYYDIDAILTTQQKLPCTFKFDIPGLGHLESSTKDIKEGSRVELSYWLAELLA-----------------SASDTLSVQEL--------------VAGTR---------------------------------------- Thetr AYYDIDAILLDDQIVPAHFNTAAMDLGVLDPSSPHIDQGTETDIPLWLALSLATLRSPSFFGESFQAHLLADAQVLNIHDKFYELGVKLAAVLKKAFHTRYLRIVDTSINEHIRKLTTAERNLHLGHAAAAEVLRYKTRD Treme1 DYFSLSSILADNHKLSCTFVLDVPGLGYLEGGDPNIHQHGKLELPFWLAQTLSTFPLPPAYSNRVRAALNASAPSVRLSNLWYRFGKRIANMLLKAFINRLPPLQDLAAH-FREGMEGDERELGIGQDSGRMVKIWYDLP Trire2 -YYDVDAILTDGEKVPCRFELDVPYLGHLDNS-SGLKAGTRLNLPLWLAEMFATLSLPPCLSEQVLAALKADPRAVPLRDQFYGVAVRMLAILRNTFVVRAADVGLHARKEFLRGLDEWERRLRRGHEGVKGAKEWTDNV Umbra1 EYYDIDAILAEHEKVPGRFNDSVGAELNLTGE--AVPSGTKVELPYWLAESLVDMETPRIYNNRVRNAIIAGPTSVDTRRIFHRLGIKFVQVLKLSFRKRLYMILDHAQTHFTRKLDETERQLKLAHDSAMAMKSWQSGS Ustma22 NYWNVDDFIADSQRLPCTFNMDVPNMGQIQSTERDIKALTRVELPFWLAELMASINKPKSFSTRVKAALDANPASVQLR--WYALGARLAQVLSKAYTGRIAQIFQQSQHDFLQGMEESERTLRNGQEGARMMKDFLASN Walse1 SYYSIDSIIADNQKVPSEFLTDVPSLGWLQGGDKDIKEGSKVDLPYWMSSTLANLSIPGAFSGRVSNALLASPTYVKLANLWYSFGLRISQSLRLAFSQRLIEIFDLGQYEFKAGMDELEKQLEHCSRSAAKHKRL---- Zygro1 GYYDVDDILADSAEFSCKFQYDMPGLGYLAGNGRAIDKNARLDLPLWLARILAELLPAEIFSPKVINAIKADPTSIDLHSIFLALSLKWISICSSLTLARALEINAHASS-FLLTLDESEKKLRTSHESYKEHKRWMVER [Cluster2280.fasta_al_trimmed; alignment length = 100] Allma1 LAQTIKSSRVLVKPLANWQANAAGYRRLGLRYDDIIMEENVQEALRRLPEVLAERTFRHKRAMQLSLCHAELPKEQ-WTKPSEDYLSPFITMVEKEFAEK Ashgo11 MGDYILKSPTLAVPVAQQFVKLSGYRQLGLKFDDLIAEENVQTALRRLPEESYARVFRIIQAHQLELTHHLLPKHK-WTKPEEDYLLPYLLEAEAAAKEK Aspfu1 L--------------------------IILRFDDLIPEESVQTALKRLPKEAYDRVFRIRRAFQCSVSHTLLPAHE-HTKPEEDYLSPIIREIERENKER Aurde31 LAPWIMKRPGLLKPISGWYVQQAGWRKVGLLYDDLIVEENVQKALSRLPQAIYDRSFRIRRAQQQDVLHSDLPESQ-WTKPEDDYLTPYIEQVVKEENER Batde5 YIRTLRNSPAL-ANLGEWHSNNMGYRKLGLRYDDMVPDNSIKEALRRLPKELMERTFRFRRALSLSLIKQEAPKDE-WTTTAQDYLRPMISLVEAEVATK Botbo1 LAPQIRASRSLFLPIAQSYANIAGYRRMGLKYDDLLVEERVQKALSRLDRESYDRVFRLKTAFQYSILHHDLPKDK-WLKESDDYLTPVIEEVAQEDSER Botci1 LASWISKKPGLMKPLASWYTNAAGYRQLGLRADDLLPEESVLLALKRLPKEAYDRVFRLRRAVQCSVQHQLLPKDQ-HTKPRRRIPLPH------HCRDR Caeel KAVTFAYNGTILRKFA--WSNLWGGREYGLQFHDTYFEPAVTEALRRLNHVFDQRKIRLSRAHTLALHGEKLPKAE-WTQWDQEYLKPYLDEIEAEKKAR Canalb1 AANFILARPTLITPLAQKFTAYAGYREMGLKFNDLLLEETMQTAIKRLPELNYSRNFRILTAHQLALSHQLLPAEK-AVKPEEDYLIPYILEAEKEAFEK Cangl IGDFILKTPLLCVPVSKQYIKYSGYRKLGLRFDDLIAEENMQTALKRLPGESYARNYRIIRAHQSELTKHLLPRNE-WVKAQDDYLLPYILEAEAAAKEK Capow MTSLRHTNVGLFNSISRWAVNASGYQKFGLFRDDLLSEDDVAEALRRLDIEQDRRIFRMKIATQLSLQQQILPREQ-WTNSETEYLQGLIQTVAKEMAER Catan2 LAQTIKSSRILLMPIARWNANAAGYRQLGLKYDDIIMEESVQEALRRLPEVLADRTYRHRRAFQLSLSHSVLPKEQ-WTKAEEDYLTPYIDMVEKEFAEK Cioin ---------------------------------------------------------------------------------------------------- CocheC53 LAPYIMKRPWLMKPLSNWYCNAAGYRQLGLRADDLLPEENVQTALKRLRQEAYDRVFRLRRAFQLSMSHQLLPKEE-WTKPEEDYLSPLITDIEAEMAER Coere1 IARALQNNSAFCKPFANTWVKLSGYRRLGLRYDDLLREETMQEAIGRLNKETDGRVYRQKRAFQLSLSHQELPYTQ-WTKPEDDYLQPLVEEVTAEFAER Conco1 LANVVRNSKFLFNPIVRVYPDLAGYRKVGLKYDDLISEENTVEAIRRLPAEQDARAFRIRRAFQCSLSHSELPKNE-WTTAEQDYLLPIIKQVELEFKER Conpu1 ---------------------------------------------------------------------------------------------------- Copci LAPYVRSSKTLVTPIANWYAQAARYRQFGFKYDDLLMEENVQRALGRLTRQTYDRAYRLKRASQCSVLHAELPKDQ-WTKPEEDYLAPHVKNVVAEETER Croqu1 VYQQIRANKSLLKPIAGWYANLAGYRQHGLKYDDLIIEENVQKALSRLSREQYDRAYRLRVAFQLSILHKELPKAQ-WTKPEDDYLVPLVKEIEAEESER CryneH991 FAPWIRQYPGVWARWSNLYRHAAGYRQKGYLLDDLVMEESVQKALSRLPRVAYDRVWRHRQGIMMSMHHTDLPKSK-WTPPEKDYLTPYINQVLAEEQER Crypa2 LAPFVTKRPWLLKPLASWYANASGYRQLGLRADDLIPEESVQTALARLDKERYDRIFRIRRAVQCSISHKLLPKSE-WTKPADDYLGPLIKVIEAETKER Debha1 TADYILSRPVLVSPVAKAFVAYAGYREMGLKFNDLLIEETMQKAISRLPEEIYARNYRFITAHQCSLSHQLLPANQ-AVKPEEDYLVPYILEAEKEAFER Dekbr2 RADLILRTPILFMPAARLFTKFSGYRNMGLRLDDLLWEENMQSAIRRLPEESYARNYRIMTSHQLSLMHDVLPDSK-AI--------------------- Dicdi ---------------------------------------------------------------------------------------------------- Dmel MSNYIARKGPALSNLGRWAYNLSGFNQYGLHRDDCLYE-NVKEAVRRLPKLYDERNYRIMRALHLSMTKTILPKEQ-WTKYEEDYLEPYLKEVVKEREER Enthi ---------------------------------------------------------------------------------------------------- Falba IARAILKSPFWLLRLSMRYVSAMGHYQYGLKTDDLLIAETMTEALRRLDTTIYERNYRFKNALQLSLEHKVLPEYM-WTNTFEDYLLNKWEAVNNEEAET Fomme1 FAPQIQKSRTLFKPFADWYAQIAGYRQIGLKYDDLLLEERVQKALGRLSREAYDRNHRFRVASQASVLHRNLSKEH-WIKPEEDYLRPHVEEVWKEDMER Fusgr1 LAPFILRRPWLFKPAATWYVNTAGYRQMGLKYDDLLEEENAQAALKRLSRESYERIYRIRRAVQCSYQHKLLPKDQ-WTTSAADYLQPLMEEVAAEKAEK Galma1 LAPYVRSSRTLVTPIANWYANAMGYRKYGFKYDDLLVEENVQRALSRLTGENYDRTYRFKRASQASVLHAPLAKSE-WMPVSEDYLEPHVTDVLKEDQER Ganpr1 FA---------TRPFGEWFSTTS-YRRMGLRADDLIPEENVLAALNRLPQEQYDRVWRIKRATQASIQQSELEPEE-WTKPHEDYLRNIVAQVEKELIER Gloin1 LYNTVKNSRFLLKPVANWYTNISGYRQLGMRYDDIIAEESVQTALERIPNEYDQRILRIRNAYQLSTRNEILPRDK-WTKPEEDYLFPYVERVAFEEAER Hisca1 LIKQINARPWLMLPLANWHANASGYRQMGLRADDLIPEENVQLALRRLPKEAYDRVYRIRRAFQLSIEHQLLAAEQ-QTKPEEDYLSPIIREIERENKER Klula1 IGDYILRTPALVVPIAHQFINLSGYRKMGLRFDDLIEEENAQTALRRLPDESYARIYRIINAHQLSLSHHLLPKDK-WTKPEDDYLTPYLLEAEAFVKEK Lacbi2 LAPQVKSSRTLITPIANWYANASGYRKYGFKYDDLLCEENVQRALSRLTREAYDRAYRLKRASQASILHAPLSKEQ-WMQPSEDYLKPHVVEVMKEEAER Lenti61 FASTIRRNRTLFKPLSDWYANVAGHRKVGLKYDDLLVEERVERAIARLTREQFDRAFRFKRASQCSVLHDNLPKDQ-WIKPEEDYLKPHVVDVVKEDLER Malgl1 LAKFIKSSPTLVQPVANAYAHAAGYRQMGLRYDDLIVEENMQKALSRVPLEQYDRVYRMRRAVQCSILQHDLPKDQ-WTKPEDDYVTPLLEEVQAADDER Mellp23 VYQQIRANKSLLKPIASWYANLAGYRQHGLKYDDLIIEENMQKAISRLTREQYDRAYRLRVAFQLSILHKELPKAQ-WTKPEEDYLSPLVKEIEAEEKER Mnele YTSQVGKTAARMFPIMRLNYRTSHQAEYGLRFDDWWFNQSVGIALSRIDIELQLRNFRGFRAAQLAIERSVAPKEERFSEILEDYCKPWYDQVMREKAEA Monbr ---------------------------------------------------------------------------------------------------- Morel2 LVNQVKASKFLLQPVANAFVNAAGYRKLGLRYDDVLREETIREAVNRLPNEGYERVYRMKVAFQYSLSHTIATKDA-TLKPEDDYLTPIIDEVAAEFAEK Mucci2 LKSLVQNSKLLLKPVSKAYAGAAGYRQIGLKYDDLISEESVQEALRRLERTAYDRAYRIRVAQQCSLSHQLLPKDK-WVTQSQDYLQPYIDEVAAEQAER Mydma MAAARAGNPSVFNAFRGWYLNASGYRALGLRIDDLLKEEDVKNAVQRLSEEYNLRAFRIKRAMDLSLKHQILPKDQ-WTKPEEDYLTPLVEAVTKERKER Neucr2 LVQAVAKRGWLLKPVSNWYINAAGYRQMGLRADDLISEENVLAALQRLSKESYDRIYRIRRATQLSLTHKLLPKNE-WTTQEEDYLRPLIDQIEAEAAEK Orpsp11 ---------------------------------------------------------------------------------------------------- Pench1 LASYIVKRPWLLTPLSHWYTDAAGYRRLGLKFDDLIPEESVQKAIKRLPKEAYDRVFRIRRAFQCSISHTLLPAHE-QTKPSEDYLSPIIREVEKEAKER Phybl2 LKNLVQSSKFLLAPVSKVYAGAAGYQKIGLRYDDLIAEESVQEALRRLEKAAYDRAYRIRVAQQLSLSHALLPKDE-WVTNQQDYLQPFIDEVASEYAER Picst3 AADFILSRPTLVNPVAKAFVAYAGYREMGLKFDDLISEESGQKAISRLPGEIYARNYRFITAHQCALSHQLLPANK-AVKPEEDYLIPYILEAEKEAFEK Plicr1 LAPYVRQSRTLIKPLATWYADLAGYRKMGLKYDDLLVEERVQRALKRLTREAYDRAYRLKLASHASVQHANLPKEQ-WVRAEEDYLKPHVLDVANEDVER Polpo ---------------------------------------------------------------------------------------------------- Pucgr2 FVQQIRANKPLLKPIATWYANLAGYRKFGLRYDDLIMEENMQKAITRLTREQYDRSYRLRVASQCSVLHKELPKEQ-WTKPENDYLTPLVKEIEQENQER Punst1 ---------------------------------------------------------------------------------------------------- Rhior3 LKSFVQNSKLLLKPLSSAYANAAGYRKIGLKYDDLVAEESVKEALRRLERAAYDRAYRIRVAQQCSLTHQLLPKDQ-WVKPEEDYLQPYIDQVSAERAER Rhoto1 FAKQLRASRTLAKKLGQKYAQLAGWRQHGLRYDDILIEESVQKALGRLSREAYDRAYRLRVASMCAIAHQELPKAE-QVKPEEDYLKPLVEEVEAEEAER Rozal11 LDVLFERNPRLFNRFRENYLNRCEYRQYGLNRDDLINEDCVKTALSRLPKVIFDRSFRIRRAVFVSSNHEKLPPEE-WTKPEEDYLFPVVMEVVAEQDHL Sacce1 IGDYILKSPVLCVPVANQFINLAGYKKLGLKFDDLIAEENMQTALRRLPDESYARAYRIIRAHQTELTHHLLPRNE-WIKAQEDYLLPYILEAEAAAKEK Salro MAFRRSLTLFAMAALGRWARNASGYRKYGLFADDLIREEMVREAISRLPEEQDLRYFRLKRALQLSVQHKYLPKEE-WTTDETEYLTPIIKQVEQELKEK Schco3 LAPRIAQSKSLFKPIAAWYTDLMGYRKYGLKYDDLILEENMFRAINRLPRELYDRGFRFKRASQASIMHAPLSKEQ-WTKPEEDYLRPHIDSVVEENKER Schpo1 LAKYIQKSPFLLLPISNAYVHLSGYRKYGLRYDDLMLEENTQKALSRLPMESYDRVYRIRRAMQLSIENKILPKSE-WTKPEEDYLRPVLAEVIAERKER Sorma LAQAVAKRGWLLKPVATWYTNAAGYRQMGLRADDLISEENVLAALKRLTKESYDRIYRIRRATQLSLTHKLLPKNE-WTTQEEDYLRPLIDQIEAEAAEK Sphar ----------MLQAVRRWAVNKSGYRKYGLRYEDICMEEANKAAIARLSEEQYDRKFRMKVALDLSAKHAILPKEL-WTTDESDYLSEGLKRLENEHAER Spipu1 MTSLLQSIRALAKNLAEWHHNLMGYRKMGLRYDDLIPEENVQGALNRLPKEYHDRVFRQRRAINLSAQQSELEPKE-WTKPEEDYLTPLVQQVENEIATK Sporo1 LASAVKNSRGLLKPLADKYAQLAGYRQHGLKYDDILIEENVQKALGRLPREAYDRVFRLRTASQCVIMHQELPKDK-QVKASEDYFKPYVSEVEQENAER Stehi1 LAPIVRKSPTLTKPFANWYVDKMGYRKVGFKYDDLLVEERVQRALGRLTAEAYDRAFRLKRASQASVQHKDLPKDQ-WTKPEEDYLKPHVVDVAQENAER Tapde11 ---------------------------------------------------------------------------------------------------- Thetr IVEQIAASPAVVHRFSESFRVASGYRKFGLRHEDIIME-CVQEAINRLPEELQERNFRFSRAINISAKKATLPAAE-RTSPADDYLTPYIRKVQQEQDDL Treme1 -----QHIPSVLKPIASIYANAAGHRKMGLRYDDLIIEERVQKAINRLPRESYDRVFRMRRGILQSAAHKHLSKEE-WVKPEEDYLAPIVEQVAKEDAER Trire2 LAPFVLKRPWLLTPAANWYANAAGYRQLGLRYDDLLEEENVQIALQRLSKEAYERVYRIRRSVQCSTIHKLLPKDQ-WTKPEEDYLRTILQQVEAELAEK Umbra1 FKSAVQNSKFLLKPVSTAYANVAGYRQIGLRYDDLIAEENAQEALRRLSREAYDRVYRIRVAQQCSLSHSLLPKEQ-WTKPEDDYLRPILEEVTAEFAER Ustma22 LAKYVQSSPALLKPVANAYANATGHRQMGLRYDDLLIEESVQKALSRLPKEAYDRAFRLRQASHLSVIHRELPKEQ-WLPASEDYLTPYVQEVANEESER Walse1 LAPFIKGS--LLEPIGKGYLNLAGFRQVGLRYDDLIQEENMQKALARLSREEYDRAWRLRRAINQSILHKDLPKEQ-WSEDEASYLTDRITEVANEHNER Zygro1 IGDYILNSPSLLVPVARQYINLSGYRKLGLRFDDLIAEENVQTALRRLPDESYARVYRIIRAHQTELTHHLLPKNE-WIQPKEDFLLPHILEAEAAAREK [Cluster2281.fasta_al_trimmed; alignment length = 134] Allma1 MYNGIGLTTPRGS--GTNGYVTRNLSRQPNKE-ILLHEQKRQVEVKCLELRLKLEDE-GEDSIDDQVGTLRKKLLA-ELTSTHQQAARKAKEAQRFASA-LGIRVHKPGEAFNRELQEQKRQEKIAERGRRTKD Ashgo11 SYNGIGLKTAKGS--STSGHIQRSLA-KLDGS-MAAHADRREIEVRVSELRDELEDA-DAEEIERRCEQLRRQLQS-EA-----------AERARVAQA-YTPR---------------RSAGAT--------- Aspfu1 MSSNVGLSTPRGS--GTSGYVQRNYARQPDKQ-ILEHDRRRAVEVKVMEERERLEEE-NEEEIEERCEALRARLLK-EMYQVHELAEAKIEESERFKKA-LGIRDTETG-------------------EPRKRD Aurde31 MYNGIGLTTPRGS--GTNGYVIRNLSREPDAE-ILEHEKKRLVEVKCFELRVQLEDE-EEEEIEEKVDTLRKSLLD-NLSDRHGLAAAKKAELEKMSAA-LGTRSYVEGEAFDREKQEQLKLQRQAER------ Batde5 MYNGIGLSTARGS--GTNGYVQRNMSRKPNQG-ILEHDRKRQIELKCLELQESLEEQ-GEDEILAQVSTLRKSMLA-DLHQVHRIAEAKEKANKRFESA-FGIDDFVEGGSFD--------QERL--------- Botbo1 MYNGIGLVTPRGS--GTNGYVVRNLSREPDQG-ILEHERKRKVELQCLELQLELEEK-EEEEIETQVSALRTRLLE-NLSDSHGIAVAKKTELARMASA-LRTSNYVEGDAFNREKQEQDKFLRNKERERKERE Botci1 MSSNVGLTTPRGS--GTSGYVQRNLARQPDKG-ILEHDRKREVEVKVFELRDKLEEE-GEEEIEIQEEALRKKLLK-EMHQVHELAEAKIKQDKKFRSA-LGISDYKEGGHW--QKQEERQRAAMEKN-----D Caeel MYNGIGLQTARGS--GTNGYVQSNLSRKPNEE-IMDHNRKRQIEVKCTEFEMLLEDK-GDEDIERKVGEYRKNLLK-QLKESHARRRAAANNRDKMRNA-LGLGDYVPGSSMDKEKLLERKSKKKQESRQKERE Canalb1 SYNGIGLQSVRGS--ATSGHIQKNIA-QIKSE-LTKHEQLRRIEVKCMDLQDELEEQ-GPDEIKARVDELRKKLNN-KE----------DENDAKSPTT-TTPQ---------------RKDKQLKEDKRRYAD Cangl G-RGVGLQSAKGS--STSGYVQRSLA-GLKKV-LVEHDKRREIEVQVSELRDSLEDK-QDKRIDEECEKLRSTLLA-DL-----------QEKEKYQKA-YTPR---------------RSSESSK-------- Capow SYNGIGLTSARGT--GTNGYIQRNLSREPNAE-ILAHERKRQVEVRCMALQDELEEK-GEAVIESRVAELREQLLS-ELSETHQLAAAQQAKNERTRSA-LGIEGYVEGSAFDPETQQRKREERIAQRERDARD Catan2 MYNGIGLSTPRGS--GTNGHVQRNLSRKANQD-ILLHERKRAIEVACAELEMQLEDQ-DQHVIEAQVAALRLKLTK-QLSSSHERAVAKHQENQRFASA-LRIDSHVPGLAFDRDAMAKRKEEELAERWEQVKD Cioin -------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MSDNVGLTTPRGS--GTSGYVQKNRSRQPDAE-ILEHEAKREIEVKVLELRDKLEDE-GEDEIDDQCEALRRKLDQ-ERHQVHDLAKAKMEESERLRKA-LGISDYEEGSHW--KKQEERMRESLAKRRYKEDD Coere1 -YNGIGLTTPRGS--GTSGHVVKNVSKPLDQG-ILEHERKRQVEVKCLELQDELEAQ-GDDAVEARVDRFRKQLHQ-NLFETQRITEAKAKENHMLASA-LRVEGYVEGAAFDRELQELRRERRLLEK------ Conco1 MYNGIGLQTARGS--GTNGYIQRNKSKQPDQE-ILLHERKRKIEIKCMELRLQLEDD-GEDEIDEKVDVYREELLKKDMYQTHQLADAKHRENKNL-------------------------------------- Conpu1 MYNGIGLTTPRGS--GTNGYVVRNLSREPDEG-ILEHERKRKVEVKCLELQLELEDE-GEAEIEVKVDELRTKLLA-DMSDTHGMAAAKKAELSKMARA-LGTRDYSEGEAFDREKQEENKIRRLTEREKRERD Copci MYNGIGLTTPRGS--GTSGYVVRNLSREPDQG-ILEHERKRAVEVKCLELQLKLEDE-EEAEIEKQVSALREKLLA-NLSDTHAIAAAKKVELERMAKA-LGTRDYQEGDSFDREKQEELKLKRIAERERRRQD Croqu1 SYNNIGLTTPRGS--GTSGHVQRNLSRKPDAS-ILEHERKRRIENKCVELQLELEDE-GEDVIEQRVQELRSKLMSEESHETHELAAMKAKENDKFRAA-MGVKSYVEGEAFDKELQQQRKQQLIEEREQVQKE CryneH991 MYGNVGLATARGS--GTNGYVTRNTARAPDQG-ILEHERKRRVEVKVMELRDELEEK-GEDDIEEECSRLRQKLMA-QPLDTHSLAAAKEVEMSRLQRA-LGVSSHEEGRAFKRETEEE-KAARLAKREWEEKE Crypa2 MSDNVGLSTPRGS--GTSGYVQRNLARQPDKG-ILEHDRKREIEVKVFELRDELEDQ-EEDEIEERCEALRKKLTA-EQHQVHELADAKIKESERLRRA-LKISDYEEGSHW--RRQEERLQKAVDKD-----D Debha1 SSNGIGLQTARGS--GTTGHIQKNVA-EAKQE-IRSHDLKRDVEVKCMELRDALEDE-SELTIEKKVNELRDKLLN-S------------PMTARKQTS-LDDR---------------DSSHASYENKRRYTD Dekbr2 SYNGIGLPTPRGT--GTNGYIQRNLAEFVDTE-LLEHEEKRRLEVKVMEYRDYLEDQLEMREIDAKVEKYREKLIA---NDELERRKKAEERAEKLKHASYGIKPFSKGSPKDSEK------------------ Dicdi SYNGIGIKTARGT--GTNGYVQRNLSKKANLE-LIEHNRKRRIEVEIAQWAE--END--QEELDALLAKKREELLEKQQTDSHSKQYQKEKEIKRFTDA-LNI-DYIPGASLDKQVQQERKEKRHQEYRDSDRD Dmel -------------------------------------------------------------------------------------------------------------------------------------- Enthi MYNNLGLRTVRGT--GTSGYVQMSKSNFMDQE-IIEHELRRKIEIMVLEW---VEKN--EKAKQEKIKEQRKYYQE-KI---------KKKELERIRRA-CKVK--------DKDFDITEVLKRIIEE------ Falba MYNRIGLSTPRGS--GTNGFVQRNLA--ADPS-ILEHERKRAIEVQCHQLRARLEAA--PDEVDMRVQALRRKL-----HESHLIAAAKVRDNDRFARA-LRL-PHAPAPRADAG-PRDGGPARLPAPDSRRRD Fomme1 MYNGIGLTTPRGS--GTNGYVMRNMAREPDEG-ILEHERKRQVEVKCLELRLQLEDK-EEEKIEEEVDALRQKLLA-NLSDTHGLAAAKKTELDKMARA-LGTRDYSEGDAFDREKQEENRMKRLVERERKERD Fusgr1 MSDNVGLNTPRGS--GTSGYVQRNLARQPDKG-ILEHDRKREVEVKVFDLRDKLEEE-EEDEIDKRCDELRQKLLA-EMHQVHEMADAKIKESERLRKA-LKISDYEEGGHW--KRQEERLRSALEKE-----E Galma1 MYNGIGLTTPRGS--GTSGYVVRNLSREPDEA-ILEHERKRKVEIKCLELQDALEEK-GEEDVEKQVEELRQKLLA-NLSDTHGMAAAKKAELSKMARA-FGTRDYQEGEAFDREKQEENKIRRIAERERKERD Ganpr1 QYNGIGLSTVRGS--GTNGYVQTNKARQPNAD-ILLHERKRQVEVKCVQLQDQLEEE-GAEEVEEKVSQLRRDLLA-HI--THRIAQQMQQRNERILQG-LGIDTHVEGQAFDWEVR----------------- Gloin1 MYGNVGLSTPRGS--GTNGYVVRNLSRKPNQE-ILDHEKKRQVELKCISLQQKLEEA-GEKEIEEEIDAFRQSMLK-SIYQTHHLSQAKLSENEKMMRA-LGINDYVEGAAFDRDLQEQKKRERIAQRNRNKNE Hisca1 MSSNVGLSTPRGS--GTSGYVQRNLSRQPDKQ-ILEHDRRRAIEVKILEERDRLEEA-NEEAIEERLDAMRKRLVA-ELYQVHELAEAKIEESERLRRA-LGIRQGEQGDQWGGRRREERERDRGNEKRDRDRD Klula1 SYNGIGLSSAKGS--STSGYVQQSLA-PAKDESVISHKAKRQIELLVSEYRDKLEDGPDDDTIDSKCEDYRRSILE-G------------NEQSRSQN------------------------------------ Lacbi2 MYNGIGLTTPRGS--GTSGYVVRNLSREPDQG-ILEHERKRNVELKCLELQVKLEDD-EEDDIQVQVAALRTKLLE-NLSDTHGMALAKKAELSKMARA-FGTRDYQEGESFDREKQEENKIKRLAER------ Lenti61 MYNGIGLTTPRGS--GTNGYVVRNLSREPDAE-ILEHERKRTVEVKCLELQLKLEDE-GEDKIEEQINELREKLLA-E-------------------------------------------------------- Malgl1 MYNGIGLQTARGS--GTNGYVQRNLSVKPDAS-ILDHERRRKIEIQCIEFQDELEEK-GEEEIQARVASLRQGLRA-RLSDTHARSAAKERESSKMQRA-LHVRDYEEGQAFDPVLQERRKQERIEERDRVDRD Mellp23 SYNNIGLTTPRGS--GTSGHVQRNLSRKPDDS-ILEHDRKRRIENKCVELQITLEED-GESLIEIQVNELRNKLLSEDQHQTHELAALKAKENDKFRLA-MGVKNYVEGEAFNKEIQLQKKQQAIEER------ Mnele MYNGIGLSTVRGS--GTNGYVQRNTARKPNKA-ILEHEQKRAVEVKCVELQEVLENQ-GEAEIEEQVSALRISLMN-----THHLAEAQHAKNEKMREA-FGIKDKENGAEKEKKLQEKRWEQDRAERERRNRD Monbr -------------------------------------------------------------------------------------------------------------------------------------- Morel2 SYNGIGLSTARGS--GTNGYVVRNLSRKPNAE-LVLHEQKRSIEIKCATLQDELEDE-GEAEIEKQVDALREKLTG---TAAAALAATQAAEREAAMVA-AAKA------------------------SSRDKD Mucci2 MYNGIGLSTPRGS--GTNGYVIRNLSKKANMA-ILDHDRKRKVEVKCMELTIKLEDE-GEAAIEEKVQELRDQLMA-DIYETHQLAAAKEKANEKMKRA-LRIKEYVEGAAFDRDLQAQLKEEKKARR------ Mydma MYNGIGVSTVRGT--GTNGYVTRNLSKKPNKE-ILEHDRKRQVEVKCLELQEDLEDE-GSEEIQVKIEELRHELLEKEGMDSHQIAEANENKNLKMRDA-FGIKDFPEGSSFKEEHQKARREAEKAERNSESSE Neucr2 MSDNVGLSTPRGS--GTSGYVQRNLARQPDKG-LLEHDRKREVEVKVFELRDKLEEE-GEDEIETRCDELRRKLLA-EMHQVHELADAKIKESERLRQA-LKISDYQEGSHW--KKQEERLKGALERERDREVD Orpsp11 -----------GS--GTNGFVQRNLSKKVDKS-IAIHDKKREIEIK---------------------------------------------------------------------------------------- Pench1 MSSNVGLTTPRGS--GTSGYVQRNSARMPDKQ-ILEHDRKRAIEVKVMEERERLEEE-NDEEIDERCDALRQRLLE-ELYQVHELAEAKIEETERLRRA-FGLRNRETG-------------------REKRRD Phybl2 MYNGIGLSTPRGS--GTNGYVVRNLSRQPNQE-ILLHDRKRKVEVQCMELQIELEDE-GEDEIEEKVQELRTRLNK-NIHETHQRTAAKEIENKKMMKA-LNIKD----------------------------- Picst3 SYNGIGLGSARGS--GTSGYVQQSLA-EAKME-IIDHNRNREVELKCIELRDELEE--QEEEIATKVDELKASLKQ-K------------RFNVSSKNN-KKEV---------------SKMGRSVENKPRFKE Plicr1 MYNGIGLTTPRGS--GTNGYVIRNLSREPDEG-ILEHERKRKVEVKCLELQLELEEK-EEDEIEEQVSALRTKLLA-DLSDTHGLAAAKKVELSRMARA-FGTRDYTEGEAFDRDKQEENKMRRQAERDRKERE Polpo MYNGIGLRTPRGS--GTNGYVQRNLSRKANLE-IIQHNELRKIELAVEEWAV--EEN--DDEIERLKQKKREEL-----SETHQAQHVKDAENLRFQNA-LKLPGYVPGTSLDQKIQEEHKLKRKQAYDRRDRN Pucgr2 SYNNIGLTTPRGS--GTSGYVQRNLSRKPDQG-ILEHERKRRVENKCVELQLELEEQ-GEEIVEARVDELRQKLLKEDVHESHEIAAMKLKENEKFRNA-LGVKSYVEGQAFDRELQAQRKAQAMQER------ Punst1 MYNGIGLTTPRGS--GTNGYVQKNLSREPDAE-ILEHERKRKVEVKCLELQLQLEDD-GEAEIDKQVSALREKLLA-SMSDTHGIAAAKKAELSKMARA-LGTRDYAEGEAFDREKQEENKLKRQAEREKREKD Rhior3 MYNGIGLSTPRGS--GTNGHVSRNLSKKANAA-ILEHDRKRQVEVKCMELRIKLEDE-GDEAIEEKIQELRTDLL---------------------------------------------------KQ------ Rhoto1 SYNGVGLSTPRGS--GTSGHIQANRSRPPDQG-ILDHERKRRVEAQCFELQVSLEDD-GADEIERQVSTLREKLLAQSEHERHQLAAAKEQADARMRAA-LGIKDHQEGAAFDRELQEQLKQQRIAER---ERD Rozal11 -------------------------------------------------------------------------------------------------------------------------------------- Sacce1 SYNGIGLKSAKGS--STSGHVQRSLALAVQKQ-IETHMEKREIEVQVSELRDRLEEE-EEEQIDKKCEALRAKLTN-EW-----------QEQQRMSSL-YTPR---------------RLTEEQHRH------ Salro MYNGVGLTTPRGS--GTNGYVQRNMSRAPDQG-ILDHYRRREIELKCAELEDSMTEQ-GEDEIEAKVDEYRAQLLE---MGTHEEAAANQVKNERLKSA-FGIADFQHGESFQKQRREERYEQRKAERSRDERD Schco3 MYNGIGLTTPRGS--GTNGYVQRNLSREPDQG-ILDHERKRQVEVKCLELQLKLEDE-EEDDIEAQVSALRERLLA-DLSDTHAIAAAKKSELDRMARA-LGTRDYVEGAAFDREKQEEEKLKRIQERERKERD Schpo1 SYNGIGLPTPRGS--GTNGYVMRNLSRVQDPS-ISEHECRRQIESKLLLYREQLLEEVSEADVEILVQKYREQLLK-ELFHSKNDDDGRLEERDDLRSS-----DYYDYPRYRKSLNSKRHVDNYNENELPRRD Sorma MSDNVGLSTPRGS--GTSGYVQRNLARQPDQG-LLEHDRKREVEVKVFELRDKLEEE-GEDEIETRCGELRQKLLA-EMHQVHELADAKIKESERLRQA-LKISDYQEGSHW--KKQEERLKGALDREREREVD Sphar MYNGIGLATVRGS--GTNGYVQRNFSKQANEE-ILEHERKRQIESKCLEKQMELEDD-GDAEIEKVVNELRERLYA---LNTHSLAAEQQKRNEKLKGA-FAIRDFVEGSSFDKEAQTVRKEKRHQEWTRDKRD Spipu1 MYNGIGLSTARGS--GTNGYVQRNLSRKPNQE-ILDHEKKREVEVKCLMLQDQLETQ-GEEDVEARVSSLRSELLN-NLYQVHQMAEAKEKANARARSA-FGI-DFVSGAAFDKELQERLKQERLQEKAEEERK Sporo1 --NGVGLSTPRGS--GTSGHIQANRSRQPDQS-ILDHERKRRIEAQCFELQVALEDE-GPDQIETKVSELRASLLAQASSERHELAQAKLAQDEKMRKA-LGITGHVEGLAFDRDAQLELKRQRQEER------ Stehi1 MYNGIGLTTPRGS--GTNGYVVRNLSREPDQG-ILEHEAKRKVEVKCLELQLELEDK-EEDEIERQVAALREK-LS-SMSDTHGLAAAKKAELNKMAMA-LGTRDYVEGDSFNQEKQEQDRMKRMAERERKEKD Tapde11 -------------------------------------------------------------------------------------------------------------------------------------- Thetr -------------------------------------------------------------------------------------------------------------------------------------- Treme1 MYNGIGLATARGS--GTNGYISRNSARQPDEG-ILEHERKRRVEVQCAELRDQMEGR-GEDEIEEAITSLRTRLSA-SVTDSHSIAQAKQIEMSRMQRA-LGVSDHQEGKAFQRETEDE-RAARLAARDREEKE Trire2 MSDNVGLSTPRGS--GTSGYVQRNLARQPDKA-ILEHDRKREIEVKVFELRDQLEEE-EEEEIDRRCDELRKKLLA-EMHQVHEMADAKIKESERLRRA-LKISDYEEGGHW--KKQEERLRESLAKN-----E Umbra1 MYNGIGLSTPRGS--GTNGYVVRNLSRQPNQE-ILLHDRKRQIEVECLKLKMTLEDD-GEDEIEAKVQQLRESLLS-KLHETHQLSEAKQFENKKMMQA-LRIQDYVEGAAFDQELQKKLKQERIAKR---QRE Ustma22 MYNGIGLKTARGT--GTNGYVQRNLSLGPDAA-ILEHERKRAVEVKCMELRVELEDD-DDDEIEERVAQLRETLNA-QLMGTHQQIQTKQHLDRRFAIA-VGVEGYRQADAFNRDLQELKKSERIHQQ------ Walse1 EYNGIGLPSARGS--GTNGYIQRNLARSPDRS-ILEHEQKRKVEIAVLELKDDLEEK-GEGEIEDKADALRQQLLA---HERHAIAAAKALEMQRINHA-FGTRNYKEGDAFDRELQERKRIERIERRELDERE Zygro1 SYNNVGLKTAKGS--STSGHIQRSLARPKDAK-LVDHLQRREIELQVSELRDQLEDG-SDETIDRKCNELREKLTN-A-----------------TRTA-YTSR---------------RENASEPK------- [Cluster2285.fasta_al_trimmed; alignment length = 64] Allma1 ---------------------------------------------------------------- Ashgo11 DARFPNQ-NQTKHCWQSYVDYHKCVNAKGEDFGPCKVFFRTFSSLCPVEWVEKWDEQRSKGIFP Aspfu1 DARFPQQ-NQTKHCWQNYVDYHKCINAKGEDFRPCRQFYHAYRSLCPKAWTDRWDNQREAGNFP Aurde31 DARFPNQ-NQTRHCWQSYVDYHKCVNAKGEDFAPCKQFKRVYRSLCPIEWVSRWDEQREAGTFP Batde5 DARFPNT-NQTRNCWQNYVDFHKCVQAKGEDFQPCQEFKAIYRSLCPTNWTDQWDEQREENVFP Botbo1 DARFPNQ-NQTKHCYQNYIDYYKCTNAKGEEFTPCKQFFRAFHSLCPNEWIARFDEQREAGAFP Botci1 DARFPNQ-NQTKHCWQNYVDYHKCILAKGEDFAPCRQFFLAYKSLCPSAWVERWDDQRDNGTFP Caeel DARFPQV-RKQRQCFAYYVDFHRCNELMGQDYKPCKFFQNVYKDFCPGFWTERWDELLSEGRFP Canalb1 DPRFPNQ-NQSKHCAQAYVDYHKCVNVKGEEFEPCKIFFKTFTSLCPLDWVEKWDDQRAAGKFP Cangl DPRFPNQ-NQTRHCWQAYVDYHKCINLKGEDFAPCKVFWKTYSSLCPVEWVEKWDDQREKGIFA Capow DARFPNQ-NQTKNCWQNFVDYQKCIKAKGEDYAPCKAFKKNYTILCPTAWISAWNDQLEAGTYP Catan2 DARFPNT-NQSKHCWQNYVDYNKCVEAKGEDFAPCKQFAKAYKALCPSIWIEKWEEHREAGTSP Cioin ---------------------------------------------------------------- CocheC53 DARFPNQ-NQTKHCWQNYVDYHKCITAKGEDFAPCNQFKLAYKSLCPSGWTSRWDDQREAGNFP Coere1 DARFPNV-NQTKRCWQNYFDYTKCVAKKGEDFPPCKQFLRTYLTVCPNEWIERWDTQKEEGTLP Conco1 DARFPHT-NQTKHCWQNYVDYNKCITKNGEDFPACQQFFKAYRSLCPAEWTTKWDDAKDNGVLP Conpu1 DARFPNT-NQTRHCFQNYTDYFKCIAAKGEDFAPCKQFKRAYNSLCPNEWISRFDEQRENGTFP Copci DARFPNT-NQTRNCWQNYCDYFKCVAAKGEDYAPCKQFKKAYNSLCPNEWISKWDEQRESGTFP Croqu1 DARFPNC-NQTKYCWQSYVDHYKCVNARGKDFPPCKQFFRAFHSLCPNSWIARWDEQRENGKFP CryneH991 DARFPNQ-NQTKHWYQNFVDYHKCVNAKGEEFAPCQQFKKAFRSLCPNDWVGQWNEQIEAGTFP Crypa2 DARFPNM-NQTKHCWQNYVDYHKCILAKGEDFAPCRQFWLAYRSLCPSGWYQRWDEQREAGNFP Debha1 DPRFPNQ-NQTKHCAQAYVDYHKCINAKGEEFEPCQIFWKTFTSLCPVDWVDKWNDQREAGKFP Dekbr2 DARFPQQ-NQTKHCYQSYLDYHKCVALKGSDFEPCKVFWHTFQSLCPHDWVENWDDEREKGIFP Dicdi NPRFPQQ-NQTKHCWANYVDYYGCVKHYNGDNSKCQTFFNSMNSLCPAAWISEWDEQKAADLFP Dmel DPRFPNQ-NVTRYCYQSYIDFHRCQKKRGEDFAPCNYFQKVYKSMCPNAWVEKWDDQRESGTFP Enthi ---------------------------------------------------------------- Falba DARFPNV-NQTKNCWQNFVDFHRCANARGEDFPVCVQFKKTFTSLCPIEWVDRWTDQVENGVFP Fomme1 DARFPNT-NQTRHCFQNYTDYFKCITAKGEDFAPCKQFKRAYNSLCPNEWISKWDEQRENGAFP Fusgr1 DARFPNM-NQTKHCWQNYVDYHKCIIAKGEDFAPCRQ----------------------SGNFP Galma1 DARFPNT-NQTRNCFQNYTDYFKCIAAKGDDYAPCKQFKKAYNSLCP--MISKFDEQRENGTFP Ganpr1 DARFPNT-NQTRNCWQNYVDYFRCVRVKGEDFAPCEQFQKTYKSLCPTKWVEKWDEQRENGVFP Gloin1 DARFPNT-NQTKHCWQNYVDYFKCIKARGEDFAPCQQFFRAYHSLCPNDFVSV---QKERNSIF Hisca1 DARFPNQ-NQTKHCWQNYVDYHKCIIAKGEDFRPCKQFYLAYRSLCPKGWTDRWDDQREAGNFP Klula1 DARFPNQ-NQTKHCWQSYVDYHKCINAKGEDFAPCKVFWKTYSSLCPVDWVEKWDEQRSQGIFA Lacbi2 DARFPNT-NQTRNCFQNYTDYFKCITAKGEDYAPCKQFKKAYNSLCPNEWISKFDDQRENGTFP Lenti61 DARFPNQ-NQTRHCFQNYTDYFKCIAAKGEDYAPCKQFKRAYNSLCPNEWIAKWDEQRENGTFP Malgl1 DSRFPNQ-NQTRHC---YVDYYRCVNTKGEDFEPCKQFFSTFHSLCPNEWLEKWDEQRENGAFP Mellp23 DARFPNC-NQTKYCWQSYVDYYKCVNARGEDFAPCKQFFRAFHSLCPNNWIARWDEQRENGKFP Mnele DPRYPAF-NQGPKCTQYFIDFQKCIWKKGEGYKPCDWFRHHYEHVCPAPWIEKWQDQLDRGVFP Monbr DARFPNQ-NQTKSCWQNYVDFHKCIALKGESYKPCGQFFKTYMSLCPLEWVEKWDEQREAGTFA Morel2 DARFPNT-NQSKHCWQSYSDYYKCINARGEEFTGCKQFFKTFKSICPNEWVAKWDEQREEGTLP Mucci2 DARFPNT-NQTKHCWQNYVDYFKCINARGEDFAPCKQFYRAYHSLCPNEWIEKWDAQREEGRNP Mydma DARFPNT-NQTKNCYQNFLDYHRCIKAKGEDFEPCQAFSKIYHGLCPNAWIEKWEDQLANNSFP Neucr2 DARFPNV-NQTKHCWQNYVDYHKCILAKGEDFAPCRQFWLAYRSLCPSGWYQRWDEQREAGNFP Orpsp11 ---------------------------------------------------------------- Pench1 DARFPQQ-NQTKHCWQNYVDYYKCTTAKGEDFRPCKQFYHAFRSLCPKAWTDRWDGQREAGNFP Phybl2 DARFPNT-NQTKHCWQNYVDYYKCISARGEEFAPCKQFFKAYHALCPNEWISKWDEQREEGTNP Picst3 DPRFPYQ-NQTKHCAQSYVDYHKCVSVKGEEFEPCKIFFKTFTSLCPVDWVERWDDQRAAGKFP Plicr1 DARFPNT-NQTRHCYQNYTDYFKCLAAKGDDFAPCKQFKRAYNSLCPNEWTSRWDEQRENGTFP Polpo ---------------------------------------------------------------- Pucgr2 DARFPNT-NQTKHCWQAYVDYHKCKNLHGPEHEASRHFYRTYNSLCPNRWIARWDEQREAGKFP Punst1 DARFPNT-NQTRHCFQNYTDYFKCIAAKGEDFAPCKQFKRAYNSLCPNEWITKWDEQRENGTFP Rhior3 ---FPNT-NQSKNCWQNYVDYYKCIGARGEDFAPCKQFFKAYHALCPNEWISKWDSQREEGTNP Rhoto1 DARFPNT-NQSRHCFQAYVDYFRCVNAKGEDFPACKTFWRTYHSLCPNEWIAKWDEQREENKFP Rozal11 DRFFYNS-NHNRACYNYYTDFHRCVRAKGEDFEGCDFFKKRVKVTCPGFWVEMFDEWLEKGLFI Sacce1 DARFPQQ-NQTKHCWQSYVDYHKCVNMKGEDFAPCKVFWKTYNALCPLDWIEKWDDQREKGIFA Salro DARFPNT-DQTKNCWQNYVDFHKCIKLKGEDYKPCGQFFRTFMSLCPTEWVEQWDEQREKNAFP Schco3 DARFPNQ-NQTMNCFQNYCDYFKCIKAKGDDYAPCKQFKRTYRTLCPNEWVAKWDEQREAGTFP Schpo1 DARFPNT-NQTKHCFQSYIDYFRCIKAKGEDFVPCKQFWHAYQSLCPMEWVERWDEQRENGTFP Sorma DARFPNV-NQTKHCWQNYVDYHKCILAKGEDFAPCRQFWLAYRSLCPSGWYQRWDEQREAGNFP Sphar DARFPNQ-NQTRACWQYFVDYQRCVKAKGEDYAPCDQFRKAYKSICPDEWSDKWTEQLEEGKFA Spipu1 ---------------------------------------------------------------- Sporo1 DARFPNT-NQSKHCFQSYVDYYRCVDAKGEDFPACKTFWRTYHSLCPNEWIAKWDEQREENRFP Stehi1 DARFPYT-NQTRHCFQNYTDYFKCIAAKGEDFAPCKQFKRAYNSLCPNEWIAKWDDQRENGTFP Tapde11 ---------------------------------------------------------------- Thetr DYRFPHTSSHTKRCWVNYNLYQRCAMDNGEDHPDCRKYYKTFRSICPDAWWENWDELLEENRYP Treme1 -ARFPNQ-NQTKHWCQNYVDYHKCVNAKGEEFAPCQQFKRAFRSLCPSETNGQWDEQVEAGKFP Trire2 DARFPNV-NQTKHCWQNYVDYHKCILAKGEDFAPCRQFWLAYRSLCPSGWYQRWDEQREAGNFP Umbra1 DARFPNT-NQTKHCWQNYVDYHKCVNARGEEFAPCKQFFRAFHSLCPNEWVSKWDEQRESGNNP Ustma22 DARFPNQ-NQTKHCWQNYVDYHRCINAKGEDFVPCKQFFRAYNSLCPNEWIAKWDEQRESNSFP Walse1 DVRFPNT-NQTKHCWQSFVDYHKCIKAKGDDYAPCKAFHRTYKSICPNTWTDKWNEQIDEGNFP Zygro1 DPRFPNQ-NQTRHCWQSYVDYHKCINMKGEEFAPCKVFWRTYSSLCPVDWVDKWDEQREKGIFA [Cluster2287.fasta_al_trimmed; alignment length = 86] Allma1 AYNQLQKEYVSGRQTLESQLKENELVQTEFELLIYKMIGPVLVKQEQAEAKTNVKKRLDFIRSEINRAEKQIKDLDVKLEKKKIEL Ashgo11 KYTQLQGELVVTRQKLETQLQENKIVNEELQALVYKLTGGVLLPVEQEEAEGNVSKRLEFIEGEIRRCEQNIKQKQEEMEGARAAL Aspfu1 ALPISSPDLIDARQKLESQQQENKGVQAEFDKLIYKIVGPVLLKQDKNEAVMAVNGRLDFIEKEIKRIEGQIKEAQEKAEKKRAEV Aurde31 AFGALQSEYVSARQRLDEQRVENEHVQQEFKTLVYKLVGPVLVQQDHAEARLTVDKRLEIIRGEITRAETQIKELSGKMDAQKAEI Batde5 AFQTLQKDYVQNRTQLESQLKENEEVSKEFKFLIYKLVGPVLVKQDTPEAVGNVSKRIEYISGEIKRVELQIKDLEEKQEKKKLEV Botbo1 AYQVIQDDLVEIRQRLDAQLSENEQVHKEFTGLVYKLIGPILVKQDQSEARANVEKRIEFIKGEIKRVETQLSDLTKKSEDKKSEV Botci1 EYQKLQTDLISSRQKLESQQQENKSVQKEFSALIYKLVGPVLLKQDKTEAVMAVDGRLEFIEKEI--------------------- Caeel KLRTLEKDRFTSRQEMEMRLTESKNVKAELDLMVYKLIGAVLVRQDLEEARSTVEKRLEFIDSETKRVEASISDISKKCTEQRDKV Canalb1 QYSQHQIKSVSFRTQLETQYQESLIVKQEFDELIYKLIGPVLLPQDHDEAYLNVVKRVEFIEREIESIETKIKEQDKIIRGIKQQL Cangl KYQSLQNELVTARQKLETQLQENKIVNEEFATLVYKLTGNVLLPVEHDDAKNNVDKRLEFIGEEIKRCEDNIRSKQQELETIRGQL Capow ELRKLQQSYVDSRTQFETQLNENKLVQEELRLVVYKLVGPALVKQDLPEAKSHVDKRIGFITTELDRLDKAMKEYDEKMNTLRGTV Catan2 AFETMNKEYVSNRQTLESQLKENELVQKEFELLVYKLIGPVLVKQEQPEAKANVKKRLEFIRGEIDRAEKSIKDLSAKMDKTKMEL Cioin EIQKVQKEIAELQKKLDSQLNQNTVVKDELEFLVYKLTGPVLVKQDLGEAKGTVSKRIEYISAEIKRQETLVADLEKQLNKHKESV CocheC53 KYQSLQADLVEARQKLESQQQENSTVKKEFDILIYKQIGPVLLKQDKTEAVMAVNGR---NSKDI---EKQIQDIQENSEKIKGEI Coere1 ALQELRKEQVDNHQKLDSQLQENEIVEKEFKLLIYKLIGPVLVPQEKGEATTNVQKRLEYIREELKRVDTRLKKLAEDQEKTSMSA Conco1 EFQNLQNEFVQNRNQLEAQLKENEAVKKEFSVLIYKLIGPGLIEQDMNEAKTNVDKRIDFIQSEIIRVELKLTELSKVQEEKKVKI Conpu1 EYQKLQTDLVDARTRLDAQLSENEQVKAEFAKLVYKLIGPTLMPQDQTEAKGNVNTRIEFIQSEIKRVEGQLKEFEAKSEQKKNEI Copci EFQKLQLSLIDARERLEAQLSENELVKKEFASLVYKLIGPVLVQQDQAEAKSNVDTRLDFIRSEIKRVEGQIKDIESKQEKAKQEL Croqu1 AYQNAQAELVTSRQKFESQLTENLAVKTEFDQLVYKLIANVLIKQDTAEAKTNVNRRIEFLKAEQSKVDEKISALQKQMETQKMEL CryneH991 SFQKIENELIEARQRLDSQLSENELVLKEFNLLVYKLIGPALVPQDSSEAKVNVEKRLEFIRSEIKRVESQLKEIEDKAGRKKEEI Crypa2 EFQKLQSELIASRQKLEAQKTENLGVSGEFKKLIYKLVGPVLLKQDKVEAEGTVNGRLEFIGKEIDRQEAQIKEVQEKIENIKAEI Debha1 EFSNSQGTLMTARSTLETQYQENKIVLNEFDNLIYKLTGPILMPQEYGEAKLNVTKRIEFIEGEIKRVETKIGDEEKKIEATREKL Dekbr2 QYNQVQSELVASRQKLETQLQENKIVKEEFDKLIYKLIGPVLLPQDQDEAKSNVEKRLDFIKREITRAEESIKKEQSKFTQSRDAL Dicdi AFQVHETELSASRSKLLTQLNENEMVKKEFDLLIYKLNGPVLFKQTKEEAENTITSRLDIINNNLKTIETNFKDIEKKAMEQRNKI Dmel SYQNLQKSCVKQRAVLESQLNENKCVLDELNLLVYKLFGPVLVKQELEESRQNVGKRIEYISKELKSSTDALENMEKDMLKHRESV Enthi AYNDKMNQLMLNRQRLLTQKNENDMVKKELEILIYKLEDGQLKEEDPLEAEMCVDQRLEYLESELKKCDVKEADLQAQVKECQKKL Falba RLSQLTQDLVEQRQVLQRQLNECLTVKKEFDLLVYKMENKRLVSLSLAESRQQLERRLKFLEESSERLEKQILARDTERNNLLLKA Fomme1 -------------------------------------------------------------------------------------- Fusgr1 DFQKLQGEMIESRQKLEGQKQENVGVQQEFERLIYKLSGPVLLKQDKFEAENTVKGRLDYIGSEINRLEDTIKETQGKLERKRTEI Galma1 EFQNLQADLIDARQRLEAQLSENELVKKEFTALVFKLIGPVLVKQDQAEAKNNVDTRLNFIRSEMF-------------------- Ganpr1 ALQEIQRQYILNRQQLDSQLRENEAVKEEFAALVYKLIGPVLVKQDLVEAKSNVDKRLEFINGEIKRAETLLKDLTNKQEKRQEQI Gloin1 EYQKIQKDLIESRQRLDSQLQENEVVQKEFKLLIYKLIGPVLVKQDKVEATTNVDKRLEYIKSEIQRVEKQLTDLNEKSEKKKLEV Hisca1 -------------------------------------------------------------------------------------- Klula1 KYTKLQGELIVARQKLETQLQENKIVSDEFSSLVYKLTGGVLLPVEQFEAKGNVEKRLEFIEIEIKRCETNIKSKQQELEVARSEL Lacbi2 EYQKLQVDLIEARQRLDAQLSENELVKQEFAQLVYKQIGPVLVKQDQAEAKTNVETRLEFIRGEIKRVEGQIKDFEQKQDIKKQEV Lenti61 EFQKIQADLVDARQKLDAQLSENELVKKEFSSLVYKLVGPVLVKQDQTEAKHNVDTRLEFIRSEIKRVENQLKDLGEKAEKKKLEV Malgl1 -------------------------------------------------------------------------------------- Mellp23 AYQDAQTELISSRRKLESQLTENLSVKAEFDQLVYKLVANILIKQDTAEAKTNVNRRIEMLTTEQ--------------------- Mnele KLQVLTKEFVSTRQQFDAQLNENDLVLSEFNRLVFKLVGPVLVKQEVTEAISTVKKRITFIKGELERCDKNISASEEKQGKSREAL Monbr EISSIQSEKVTTIDQLNTQLGENKLVAQELDLVVFKLVGPALLKQDLDEAKANVAKRIDYITKEIERYTKLVKDCQTREEAAEQKE Morel2 AYQTLQKDYVEARQRLDSQLQENKLVQDEFKLLIYKLIGPVLTKQDKAEAVTNVDKRIDFIQAEIDRVEKQLKDLQEKTEKKRMEL Mucci2 TFQLLQKELIESRQRLESQQQENELVNTEFEHLIYKLIGPVLVKQDKSEAATNVKNRLNLISSEIKRVETQLNELTQKSEAKKQEV Mydma IFQKLQKDFLNGRQQLDIQYNENKIVKDELDLLVFKLVGPVLVKQDLSESKLNVQKRIDYIQAELARHDKSIKEIQEKQEEKKEAL Neucr2 EYQNLNKELVLARQKLEAQKQENVSVQNEFEKLIFKLVGPVLLKQDKMDAENTVKGRLEFISKEITRLEGVIKETQGKIEKKRTEI Orpsp11 --------FVTSRQQLESQKQENESIQQEFKELIYKMIGPVLVKQDKADATHNVDKRLEYINGEM--------------------- Pench1 EFQALQTELVDARQKLESQQQENEGVQTEFAQLIYKLVGPVLLKQDKSEATMAVNGRLEFIEKEIKRIEGEISATQGKSEKMRSEL Phybl2 AFQQLQKELIESRQRLDSQQQENELVNKEFGLLIYKLIGPVLVKQDKSEATTNVKNRLDLIGSEIKRVENQLKELTEKSEMKKNTI Picst3 EFNQQQNSLITARSQLETQFQENKIVLTEFESLIYKLTGPILLPQDYSEAKMNVSKRIEFIEGEISRVETKISDEEKAMEATRQKL Plicr1 EYQKLQLDLVEARQRLDAQLSENELVKKEFTQLVYKMIGPVLVKQDQGEAKANVQTRLEFISGEIKRLEEKLKDIEGKSEKKKNEV Polpo EFQTHEKELAQARTTLLTQQNENELVKKEFDLLIYKLIGPVLFKQSKTEAETTIAARLDLITKNLKQVETNYKDTEKKALDQRNKI Pucgr2 EFQESQAQLINSRQTLDSQLSENESVKEQIENLIFKSIANVLVKQDLAESQSNINRRIEFLKHEQSKVDKKIESVQANMDRLRPIL Punst1 -------------------------------------------------------------------------------------- Rhior3 AFQVIQKELIETRQRLESQQQENELVNKEFEHLIYKLIGPVLVKQERGEAVTNVKNRLNLITSEIERVEKQLTELTKKSELKKQEI Rhoto1 AYSKLETDYVEARQRLDAQKTENESVKKELAALVFKLVGPILMKQEPDEAKQNVDKRLEWIGGEIKRVETNLKDLETKLETRKVEI Rozal11 SYQDLQKESISTREKLEAQLRENEAVLAELKLIVFKIVGPVLIDQELDEAKTTISKRLEFINKEIKRAEGVIKTVQKKQQDTAAKK Sacce1 KYQQLQNELIVARQKLETQLQENKIVNEEFDQLVYKLTGNVLLPVEQSEARTNVDKRLEFIETEITRCEKNIRDKQEELEKMRSEL Salro GMQQLQTEKIQTREKLQTQLSENKMVKQELDLVVYKLMGPALIKQDSREAQTNVGKRLEYIEAEIKRYEKLMDDNEAKAAKAQEKV Schco3 EFQKIQLELVEARQRLDAQLNENELVKKEFAQLVFKQIGPALIKQDQAEAKSNVDTRLSFIQAEIKRVEGQLKDIQQRQEKKKAEI Schpo1 KYQNLQTELVESLKKLETQLQENTTVLNELEKVIYKQIGPTLVKQSHEEAKTNVKTRLDFINKEIARLENQTKISQEEFSKVKGAI Sorma EYQNLNKELVLARQKLEAQKQENLGVQQEFEKLIYKLVGPVLLKQDKMDAENTVKGRLEFISKEITRLEEVIKETQGKIEKKRTEI Sphar ELRKIQKEYVNQRGTLEAQLMENEIVKQELDFVVFKLVGPVLVSQELAEAKDTVAKRIDYIKKEVERQTKLGQDLEVQLNEKRDKI Spipu1 AFQNLQKDFVQSRTQLESQLKENEMVAKEFDLMVYKLIGPVLVKQEKVEATSNVKKRIEFITSEIKRLETQIKDLEQKQDAKRAEV Sporo1 -------------------------------------------------------------------------------------- Stehi1 EYQKLQIDYVEARQKLDAQLSENELVKKEFLTLVFKLVGPVLVKQDQNEAKQNVNTRLEFIQGEIKRIEAQLKTLGEKNEAKKMEL Tapde11 KFQAIQQKLVESRQRLESQLQENESVKAEFDILIYKLIGPVLVKQDNIEANQNVARRIELLKQETEKVENEIKKIQQEAEKVKTEI Thetr EEQTAQVELVQSRAGYAARLNENTMVKEEFDLLVFKLIGPALVLQDVDEAKQNVEKRLEYITAEMGRLDGAITAKEGVVQAAQKKV Treme1 TFQKAEQELIEARQRLDSQLSENELVLQEFKLLVYKLVGPSLVPQDQEEARTNVEKRLEYIRNEIKRVEGQLKEAQEKVSNKRTEV Trire2 ------PDLVASRQKLEGQRQENLGVQKEFENIIYKLVGPVLLKQEKFEAESTVKGRLDFIGSEITRLEGQIKETQANIEKKKTEI Umbra1 AFQKLQKDLVESRQQLDSQRQENELVKKEFDLLIYKLVGPVLVKQERTEAFANVKNRLDLINAEIKRVEAQLQDLTQKSEKKRTEI Ustma22 EYQKLQDSFVEARQQLDSQLRENEQVAREFSKLVYKLIGPVLVKQDQVEAKSNVEKRIEFIKAEIDRVEAQIKDFTEKTDKKKIEI Walse1 EYQQVAQKLIEVRQKLQIQYNENNQVKEEFSKLVYKIIGPALVEQSQQESKLNVDKRIEFIQSEIDRTENEISTTQQKMQTLQQTI Zygro1 QYQKLQGELIVARQKLETQLQENKIVDDEFNGLVYKLTGNVLLPVEQDDARTNVSKRLEFIQTEIDRCENNIKGKQEEQERVKAEL [Cluster2294.fasta_al_trimmed; alignment length = 81] Allma1 TRFLQLQRIVHPDAAVMNKAWACL-KDELARAKHCDPDLLMFVMETREQVDELATAVQEEIGAIRDQVIKLRYFYNIMEAI Ashgo11 REYRQLQGQHHPDAQRLNRAYGTL-VRPLARAQFLDPGLLMRVLDVHEQLERLREENRARMAGAAQLAVELRYWDNVESAV Aspfu1 REFLRLQNVIHPDSARINEAYRTL-SDPLQRAQYLDPETLMEVMEVQERIEALKKENDARVAAARQECVRLRFWYSVGEGL Aurde31 AAFLRAQQVCHPDSALVNKAYRTL-ENPRTRAEYIDPELVMKVMEMRERLEEVAAENREEMNSAKLETIKLKYLEGIDAAA Batde5 --------------------------------------------------------------------------------- Botbo1 QYFLNAQRICHPDSSMLNKAYTTL-LSPLKRAEYLDQEFILEILDAREELEDIRARNQERIDAAKSECVRLRYWNGIESAS Botci1 NEFLRLQASAHPDSALINEAYKTL-QSPLLRAQYLDNELLMEVLETREEMEGLKARNEERIVKARRETVRLRYWVNVRDSL Caeel QKFHQLQSKLHPDSRKLNEAYKEL-ADPFKRAKYLNSEILMEMLERNEEIDAEKSRIETEIDEARDVIGRLTYLYSLKNTV Canalb1 REYRSLQSESHPDSSNINRAYTTL-KNPYTRIAHFYKEMLMQVMEAHEQLETLEAENKERIKTLMMDAIRLKYWVNIQNGI Cangl KEYRKLQAEVHPDSSLLNKAYHAL-KDPLTRSQHMDPELLMDVMDVHEQLLEIEKVNKQRIEKAINLTARLKYWKNVASAV Capow RLFRQLQWKLHPDSSTVNKAYDVL-KVPLKRAQYLMPELLMEVMELNERIDEIAADIEDQLQHAKQWTIILKYYYNLQQAA Catan2 RHFLTIQRAIHPDSAKVNKALDVVGKDRVARGEYLSPDLLMFIMETREQIQ----AVQQEVAVAKEAAARVRYFRNVLRAV Cioin NKFKKLQKLLHPDSSKLNKAYFCL-AKPLSRGLYMDPEFLMEIMELNEQIAEIQSTVKSHLEEAKEHLIRFKYYNNIDEKL CocheC53 REFLQLQARAHPDSARINEAYKTL-QNPLLRAQYLDPELLMEVLEARESIEEMRQRNEERIAQAKSEAVKLRYWVNIKESI Coere1 RNFLRLQQAVHPDSSWINHAYSAL-KDPLLRAHYLDPELLMEIMELREEIESLRQANDSRISSAQQLTNKLQYLRRVAQAI Conco1 KEFLQLQRKVHPDSSLLNKAYQTL-KDPLLRAKYMDNSLLFEIMELHEEIQSILDTTRDQISSAKINTIKLKYLVNVYTTA Conpu1 RRYHAAQRLCHPDSNVVNAAYNSL-LSPLQRAEYIDMELIEEIMEMREEIETLREMNNAKIQELHTAAVRLKYLQGIEDAV Copci QRFRAAQSVCHPDSARVNHAYQTL-LEPLSRIEYIDPEFMMEIMEAREAIDAIFEENTGRVAEAKLGAIRLRYLQGIQRAA Croqu1 KQYHRWQQVVHPDSIAVNRARTTL-ESDVKRAAYMDPEFLMTLMETHEQLEEIRVINSGM--------------------- CryneH991 SNWVRRQRELHPDSGRVNEAYAVL-GDDLRRAEYIDPMLLAEILEAREELERIRQANKEHVAGAKLLAVQLRYWMNLEKAA Crypa2 REFLQLQAASHPDSSHINTAYKTL-SSPLLRAQYIDPDLLTEVLYARETIEGVRVENEERIKTAVRETVRLRYWENIRESV Debha1 REYRTLQSEHHPDSSLLNKAYSTI-SNPYSRIAHLYKNMLMMVLEAHESLEALSEENDERIVEIMMEAVRLKYWINIQKGI Dekbr2 KEYRKLQAANHPDSSLINAAYSTL-NDPLKRSQYLDREILMQILDIHESLEKARDENKTRMKGIALETIKLKYWYNIKNAL Dicdi HRFKKLQKQLHPDTTSLNTAHNIL-KSPFLRAEYIDPEVLMEVLEVREAIDKIAHENRQKINDALKQTVYLRYLTRIQEEV Dmel RSFRQLQTIVHPDSSLINKAYKTL-STPIDRGQYLNKEFLMAMMERNEEVENLNIQLIKELEEVKETLVEMKYLLSIQNSI Enthi --------------------------------------------------------------------------------- Falba SLFLEQQMLMHPDSKAVTEAHRVL-RDPVQRAFALDSELLMLAFMAQETIEDLAAENDQRTQEAQKVALRLRYWQTITNGL Fomme1 RRFLQAQRICHPDSSTLNEAYKTL-QSPVLRAQYIDRGLVMEIMEAREQVDRFRSENEGKMKAARDAVVELKYLEGIQLAA Fusgr1 REFLRLQARAHPDSALINEAYKTL-SNPLLRAQYLEPELLMLVLEAREEIEEPRAANDARIAEAKHEAVRLRYWVNIKESL Galma1 NRFRQAQAACHPDSSRLNEAYQSL-LHPLSRAEYIDMEFMVNIMETREAIEELTEANEAEIAQVKAATIRLRYLQGIQRAT Ganpr1 HVFLRLQQDVHPDSSFINKAYQTL-KDPLPRALYLDTELLMEILELREELEDIRSRNDVVTDKLKRLVIELQYRVNVRDAC Gloin1 RNFLLLQQRVHPDSSLINKAYQVL-RDPLSRAKYMDQELLMEILDVREQLEAIKNESEDKINNAKELTVKLQYWYNIRNAT Hisca1 QEFLRLQARAHPDSARINEAYRAL-ADPLSRAQYLDMETLMQVLEVQEIIEKLKDENEERIKGARKECVRLRFWYTIRDGL Klula1 KEYRQLQSEHHPDSSELNRAYKTL-SKPLPRSQYIDPQLLMLVLDVHEQLEQIEQENKQRLNEAAMLTVELRYWSNLDNAI Lacbi2 RKFIQAQAVCHPDSARVNNAYQTL-LHPLARAEYIDIAFMTDIMEAREVIEDIIDKNNQSISEVKASAVRLRYLEGIQRAA Lenti61 NEFRAVQTVVHPDSSRVNEALHRL-SNPLRRVEYIDMELLMDVMEAREGLAEIRTANDAKIQELRTAAIKLKYLQGIESAA Malgl1 --------------------------------------------------------------------------------- Mellp23 LQYHRWQQLVHPDSILVNQARATL-EDDVKRAAYMDPNLLMTLMEAHEQLEEIRRANKEMIQEARALAIKLRYLETIDNNC Mnele RVYKRLQAEFHPDSALINEANKCL-KDPYCRARLLDMEFLSDMMDVNDEVERLKEVNEAAIAEAAERLAKVKFLLQTRDRI Monbr RRQRELLRAHHPDTAAINRAGTVL-LDPIERALALSAEFLMEMMERHEVREQLASQVEEECAAARDGTLRLKYLINFLNSV Morel2 LKFFKIQQLIHPDSSLANKAYSTL-KEPLSRANYIEPELLMEVMEARELLEELKNVNDKRIKDAKTLAIELQYWIRIQNVI Mucci2 RQFLMLQQKAHPDSSVINKAYHTL-KDPLSRAQYLDPELLMEVMEFREELEPLKARNDEKYAEAKDLAIELQYLNSIKTAI Mydma EYYIKLQTRLHPDSAVINEAHKVL-SDPLKRGLYLDNDFISSIFALNFQVEIMLSNIDADIKHAKRELIKMRYRRNLKQLI Neucr2 REFLRLQAASHPDSSLINSAYKTL-SSPLLRAQYLDPTLLMTVLEAREQIDPVREENEARIKEATRECVKLRYWMGIREGC Orpsp11 --------------------------------------------------------------------------------- Pench1 REFLQLQGLVHPDSARINEAYRTL-LDPLQRAQYIDAETLMEVMEVQETIEELKKENEGRVVEARKECIRLRFWYSVGEGL Phybl2 MKFLRLQQKAHPDSSVINKAYNTL-LDPLVRAHYMDPELLMDVMEFREELERLKKVNDEKYREAKEYTVQLQYWARIRRVI Picst3 REYRTLQSENHPDSSVINRAYSTL-RNPYLKIAHFYKDMLMTVLEAHEALEDLAIENDARIKEIIMEAIRLKYWVNIHNGI Plicr1 AQFHVAQRVCHPDSTYVNEAYQTL-LDPFRRAEYLDMDLLMSIMEAREEIEDVARKNQEQIDKVKDATVRLKYLQSIQTAA Polpo HRFKQLQKKLHPDSTLINSAYNIL-KSPFLRAEFIDPEVLSEILEVREEIEEIAHDNRAKMNHALGKTIYLRYLTRIQEEI Pucgr2 KAYHQWQQVVHPDSVLVNRAKSIL-SDDLKRAEYLNSQLLVEIMEVREQLESIKLTNKESIDQLKESIIRLRYLKKIQEII Punst1 HRFRNVQRVVHPDSSHVNDAYKTL-VSSTRRAEYIDPELIMEVMEAREALEKIRRQNRERMIEAKEATIRLRYLRGIDEAA Rhior3 ----------------------------------------MEVMELREELEVVKEKNDEKFKEAKELAIELQYWSSIQNAI Rhoto1 RTFLQMQQKVHPDSGRVNDAYKAL-TNERERGEYLDPELLMTIMETREELEALRERNQESTKSARNLVIELKYLNNIDQVC Rozal11 NRFLALQRQVHPDSSLINKAYQTL-SDPILTIEYVDTEYLASVMEKMEEIEELMKEQLKEMKECQSYLTMYYYKRRAFNAC Sacce1 KEYRQLQAQHHPDSSTLNQAYHTL-KDPLRRSQYMDPQLLLKVLDIHDELSLLEKQNKERIQDAVKLTVELKYWYNLAKAF Salro QTFRSLQTKLHPDSAVVNDAYNAI-RTPLSRALHLDIEFLMEVMELNEQLAAFEESLTARRDEAKEATLALRYFDNLQDQV Schco3 QRFREAQTNCHPDSAQINKAYQTL-LNPLSRAEYIDMEFIGQIMMARESIETAAEEAAEQISEMKDSTVRLKYWEGIQRAA Schpo1 SSYLRKMKTLHPDSAELSKAYNTL-KAPLTRAEYIDPEFLMEIMDVHENISQLSQENQGRKVQALLYVNRLRYWNTIDKIL Sorma REFLRLQAASHPDSSLINSAYKTL-SSPLLRAQYLDPMLLMTVLEAREVIDPVREENEERVKAAREECVKLRYWMGIREGC Sphar SQYRRSQTLLHPDSSLLNKAFRTL-RDPLQRGLYLDPAFLMEIMDINEAIEVVHEENKKQIGDAHTLMGRLQFYENINQLT Spipu1 NKFLRLQQAVHPDSSFINKAYQVL-RDPLQRAQYLDPALLMEVLDARERLEEIRRENEKRMEEAKRLAIQLQYWVNIKKAA Sporo1 RQFLQLQQKVHPDSSRVNQAWKTL-SNDRERAEYLDPELLMSIMETREALEQIRTLNSESIKEARNLVIQLKYLDNVETVC Stehi1 QKFRQVQRFIHPDSSVVNTAYQVL-LNPVSRVQYIDKQFIMEVMEAREEIEEIRDTNKLKIEATREAAVRLKYLQTIEDAA Tapde11 REFLKMQQKVHPDSSLLNKAYTTL-QQPLPRAEYLDSAVLMTVMDAREQIEGVKQEAKELIDNAKTSAVKLRYWLNIQKAA Thetr TAFKKAQRAMHPDSALCNKAVGVL-RDPIERAMYLEPELLMEVLEAQEEVAQLQAQAEARCASAQRKAIEMKYWNNIREAA Treme1 NRALERQKQLHPDSGKINKAYEIL-SDPLKRVEYIDPGLLSEIMEARESLHKIREENHLKVTTAKILAVQLKYWQGLENAA Trire2 REFLRLQARHHPDSALINEAYKTL-SNPLLRAQYLDPSLLALVLEAHEEISELRRTNDERIRQAKKEAVRLRYWVNIKESL Umbra1 MSFLRKQQRVHPDSSYLNKAYNTL-KDPLARAQYMDPELLMEVMEIREQMEKLKQENIDKIEQAKELTIQMQYWDNIRRAI Ustma22 RAWRLKMAVTHPDSALINRAYETL-LHPLSRAFYLDPELLMEVMELRERLEEVRADNAKLLEAAREASVQLRYWTNIEKAA Walse1 KHFLNKQKLYHPDSSLVNKAYETL-LHPLSRAVYIDPDLLMEILDLREQLESLRETNKEAINSAKNLTIKLRYLTNLDTAA Zygro1 KEYRNLQAQHHPDSSLLNKAYHTL-KEPLPRSQYMDPSILMQVLDTHEQLENIDLENRDRIKGAARLTVELKYWVNLAKAI [Cluster2297.fasta_al_trimmed; alignment length = 69] Allma1 HLKLIDIYLFLLYSGIAQFVYVLLA-GSYPFNAFLAGFGSAVASFVFAVSLRMRQAFGEFVICNVLLHF Ashgo11 RLLLIDTLCGLVTIGLVQVLFIAVIRDTFPFNAFLAGFISCVGQFVLLISLRLQRAFGEFVLASLVLHF Aspfu1 RTMMLDAFMFLLFVGAVQFLYCVLA-GNYPFNAFLSGFCAAVGQFVLTASLRMQRAFADYIFGSLILHF Aurde31 RLKLIDAFLFIMLSGAIQFAYCVLV-TNYPFNAFLAGFASCIGQFVLTASLRSQRAFADFALGSIVLHF Batde5 SIVLIDVYLFVMLTGIIQFLYVVLA-GTYPYNSFLAGFICSVGSFVLAVNLRIQRAFADFAFSSVLLFG Botbo1 KLQTIDAFLFIMLSGIFQFLYCVLV-SSFPYNAFLSGFSSTVGQFVLTASLRSQRAFADFVLGSIVLHF Botci1 RTKLIDVFMFLVVVGVLQFVYCILA-GNYPFNAFLSGFSATVGQFVLTASLRIQR-------------- Caeel KLKIIDAYMYILFTGIFQFIYCLLV-GTFPFNSFLSGFISTVTSFVLASCLRMQRAFADFIFANLILHL Canalb1 RLKLIDLFLFLVLLGILQFIYVLII-GNFPFNSFLGGFISCVGQFVLLVSLRLQRSFGDFIFASLILHF Cangl KLKLIDIFCFLVLVGGIQFLFALLVRDSFPFNAFLAGFIMCVGQFVLLISLRLQRAFAEFIIASLTLHF Capow LIKVIDAYLYIMLTGIAQFVYCALV-GTFPFNAFLAGFISTIGSFVLAVGLRLQRSFADFLFCHVVLHF Catan2 LLKLIDTYLFMLMSGIIQFVYVLLA-GNYPFNAFLASFGNAVASFVLGVSLRMQRALAHFVIGQILLQF Cioin KLKIIDSYLYILLTGIIQFLYCALV-GTFPFNSFLSGFISCVASFVLAVNLRLQRAFADFLFAHVVLHL CocheC53 RTKLLDIFLFLVVVGALQFAYVVVV-GNFPFNAFLSGFSATVGQFVLTASLRIQRAFADFVLGSLLLHF Coere1 RLKVIDTYMFCVAVGLIQFVYCVLV-GTFPYNAFLAGFGSAVACFVFAANLRIKSAFAEFVLCHIVLHF Conco1 SLRLIDVYLYIMLSGIIQFVYMLLA-GTFPYNAFLAGFISTVGSFVLAVNLRIQRSFSDFVVCNLILQF Conpu1 RLKLIDAFLFIMLSGIVQFVYCVLV-TNFPFNAFLAGFSSCIGQFVLTASLRSQRAFADFALGSIVLHF Copci RLKFIDSFLFLMLSGIIQFVYCVLV-TSYPYNAFLAGFASTVGQFVLAASLRSQRAFADFALGSIVLHF Croqu1 SLLLIDALLFLMVSAVLQFAYCVLL-TDFPFNAFLGSFMAHVGQFVLAASLRSQRAFADFVFGSLTLHF CryneH991 RVKLIDAFLFILLSGILQFAYRILV-TVYPFHAFAGGFGSTVGQFVLLAGLRAQRAFADFCAASVVLHL Crypa2 QTRLLDIFLFLVLVGGLQMLYFLAG-GRNPYNAFLAGFIATVGQFALTVSLRMQRAFADFIFGSLILHF Debha1 RLKLIDIFLFLVLLGILQFAYVLLV-GNFPFNAFLGGFISCVGQFVLTVSLRLQRAFGDFIFASLILHF Dekbr2 KLRLIDTFLFLVCIGILQFIFCVLV-GTFPFNGFLGGFISAVGQFVLTVSLRLQRAFGDYIFASIILHF Dicdi KLKIIDLFLYTFITGVIVFTYCCLV-GTYPFNSFLAAFISTVGCFVLTVCLRIQRAFTDYLLCNLILHL Dmel KLKLVDIYLYILLTGIIQFVYCCLV-GTFPFNSFLSGFISTVSCFVLAVCLRLQRGFADFIFAHVILHL Enthi RLKMIDCFLYQLITAALVLVYGFFF-CHNPLNAFLAALFSCAGMFVFTMSLRLHKYFVEYVFCVILLQL Falba RFVVLDVYIFLLVVG--QLAYGAIW-GTFPFNALLAGIFGCAGCSVLGAILRSQRAMLDFIVSSLVLFF Fomme1 RLKLIDAFLFIMLTGIAQFLYCILV-TNFPFNAFLAGFASSVGQFVLTASLRSQRAFADFAFGSIILHF Fusgr1 RIMLLDVFLYLVVVGAIQFVNCAIA-GTFPFNAFLSGFCVTVAHWL--------KRGGSY--------- Galma1 RLKFIDSFLFLMLSGVVQFAYCVLV-SNFPYNAFLAGFSSTVGQFVLTASLRSQRAFADFALGSIVLHF Ganpr1 RLKFVDAYLFLVLTGVLQFVYVLLV-GNYPFNSFLAGFGGAVGSFVLAASLRIQRAIAEFIFAQIVLHF Gloin1 NLKLIDAYLFILFSGIFQFTYCVIV-GTFPYNAFLSGFISCVGSFVLAVNLRMQRAFADFVFSNILLHF Hisca1 RTLMLDSFMFLLIVGGVQFLYCILA-GNYPFNAFLSGFSAAVGQFVLTASLRMQRAFADYVFGSLILHF Klula1 QLLLIDSFLFLVVLGVVQFLFVLLIRDNFPFNAFLSGFIICVGQFVLLVSLRLQRAFGEFIVASLVLHF Lacbi2 RLKFIDSFLFLMLSGIIQFAYCILV-SNYPYNAFLSGFSSTVGQFVLVASLRSQRAFADFAIGSIVLHF Lenti61 RLKTIDAFLFLMLSGIIQFLYCILI-TNFPFNAFLAGFASCVGQFVLAASLRSQRAFAEFALSSIVLHF Malgl1 RFKLIDAFLFLFVTGILQFVYCIVL-SNYPFNSFLAGFSATVGQFVLSLALRLQRAFAEFLFASVVLHF Mellp23 SLLLIDSFLFLIISAVLQFTYCIAL-TDFPFNAFLGSFLAHVGQFVLGASLRSQRAFADFVFGSLVLHF Mnele KLKLIDAYLYIMFTGIFQFVYCCLV-GTFPFNSFLSGFISTVASFILGVCLRIQRAFADFIFAHCVLHL Monbr --------------------------------------------------------------------- Morel2 SLKLIDSYMYVLLTGIIQFVYVVIA-GTFPNNAFLAGFISTVASFVLAANLRIQRAFADFLACNVVVHF Mucci2 SLKMIDVYLYILFTGIFQFVYMALV-GTFPYNAFLGGFISTVGSFVLAANLRIQRAFADFVVCSLLLHG Mydma KLKIIDSFLYVMLTGIVQFVYCCLV-GTFPFNSFLSGFIACVGTFVLGVCLRVQRAFADFIFANVVLHL Neucr2 RTKLLDAFMFLVVVGGLQFLYCVLA-GNYPFNAFLSGFSATVGQFVLTASLRIQRAFADYLVCSLILHF Orpsp11 RYKILDAYMFVVMMGVIQFVYCFII-GKEPWATFLAGFISCVGTFVLV--------------------- Pench1 RTLLLDAFMFLVLVGGLQFVYCVLA-GNYPFNAFLSGFSAAVGQFVLTASLRMQRAFADYIFGSLILHF Phybl2 SLKFIDVYLYILISGILQFIYMLLA-GTFPYNAFLAGFISTVGSFVFAVNLRIQRAFADFAVCSLLLHF Picst3 RLKLIDLFLFLVALGILQFVYVLLV-GNFPFNAFLGGFISCVGQFVLTVSLRLQRAFGDFVFASLILHF Plicr1 RLKFIDAFLFIVLSGVLQFLYCVLI-TNFPFNAFLAGFSSSVGQFVLTASLRSQRAFADFALGSIVLHF Polpo --------------------------------------------------------------------- Pucgr2 SLLLIDSVLFLIGSAVIQLAYCVLV-TSFPFNAFLGAFSVHVGQFVLLASLRSQRAFADFVFGSLVLHF Punst1 RLKFVDAFLFLMLSGVAQFVYCVLV-TNFPFNAFLAGFGSTVGQFVLTASLRSQRAFADFALGSIVLHF Rhior3 SLKLIDVYLYIMLTGIFQFIYMLVV-GTFPYNAFLGGFISTVGSFVLAANLRIQRAFADFVVCSILLHG Rhoto1 RLKLIDSFMFLMLTGIAQFAYCFGI-TNYPFNAFIGGFAATVGQFVLCAALRIQRAFGDFLFASMLLHF Rozal11 KLKIIDSYLFCVLTGIIQFVYCALV-GTFPYNAFLSGFGTSVGCFVLATNLRFTRSVADYVLCSILLFA Sacce1 KLKLIDTFCFLVLLGVIQCTFIILIRDNFPFNAFLAGFIICVGQFVLLMSLRLQRAFAEFIVASLILHF Salro TLKIIDAYLYILLTGLIQFVYCALV-GTFPFNSFLSGFISSVGSFVLAACLRSQQAFADFIFGHLILHL Schco3 RLKFVDSFLFLILSGVIQFLYCILV-TNFPFNAFLAGFGSTVGQFVLTASLRAQRAFADFAIGSIVLHF Schpo1 SLKTIDAFLFLVVVGGLQFGYALLV-GTYPFNSFLSGFISCVGQFVITVGFRMARAFLEFCFSSLVLHF Sorma RTKLLDAFMFLVVVGGLQFLYCVLA-GNYPFNAFLSGFSATVGQFVLTASLRIQRAFADYLVCSLILHF Sphar KLKAIDCFLYVMAVGVIQFVYACLV-GTDPFNSFLAGFLSCIGTFVLTVSLRMQRAFADYILCNAILHI Spipu1 SLKLIDTYLFVMLTGIIQFVYVLLA-GTYPYNSFLAGFGASVGSFVLAANLRMQRAFADFAFASLVLFG Sporo1 RLKLIDGFMFLMLTGIAQFVYCVLV-TNFPFNAFLGGFAATVGQFVLCGALRIQRAFGDFLFGSLILHF Stehi1 RLKFIDSFLFLVLSGVLQFTYCVLV-TSFPFNAFLAGFASSVGQFVLTASLRSQRAFADFVFGSVVLHF Tapde11 --------------------------------------------------------------------- Thetr RLKVIDAFLTAVLTAVVQFVYCMLV-GTFPFNSFLAGFFSAVGSAILLVCLRIQRAYADFVLCNVILHL Treme1 RIKLIDTFLFLLLSGVLQMAYRIVV-TSYPYNAFLGGFGAIAGQFVLLAGLRVQRAFADFCAASVVLHV Trire2 RTKLIDVFLFIAVVGALQFLYCILA-GNYPFNAFLSGFGATVGQFVLTISLRIQRAFADYVVCSLILHF Umbra1 SLKFIDIYLFIMGSGILQFVYMLAA-GTFPYNAFLAGFISSVGSFVLAANLRIQRAFADFAVCSILLHL Ustma22 RLKVIDAFLFLMLSGMIQFLYCALI-TNFPFNSFIAGFASTVGQFVLAASLRIQRAFGDFLFGSVILHF Walse1 RYKLLDSFLALCISAVIEFLYALAI-NNSPYNAFLGSFISKVGQFILTVNLRMQRAFADFVFASLVLHF Zygro1 RLKLIDIFCFLVVIAGVQTLFMALIRDTFPFNAFLSGFIICVGQFVLLISLRLQRAFGEFVIASLILHF [Cluster2301.fasta_al_trimmed; alignment length = 62] Allma1 ELIDKCIGSRLWVIMKSEKEFTGTLVGFDDFVNMVLEDVTEFTQILLNGNNIVMMVPGGEGP Ashgo11 EIIDRAINQPIWVLLTSNREFTGTLVGFDDFVNVVIEDVVEY-RMLLSGNNITVLVPGGKPP Aspfu1 ELIDKCVGSRIWVIMKGDKEFSGTLLGFDDYVNMVLEDVTEFDKILLNGNNICMLIPGGEGP Aurde31 ELIDRCIGSRIWVVMKTEREFTGTLLGFDDFVNMVLEDVTEYEQTLLNGNNICILIPGSTGP Batde5 ELVDRCVGSKLWVIMKGDKEFTGTLLGFDDFVNMVLEDVTEYEQLLLNGNNICMVM------ Botbo1 ELIDRCIGSRIWVVMKSEREFTGTLLGFDDFVNMVLEDVTEYEQTLLNGNNICMLIPGSAGP Botci1 ELIDKCVGSKIWVVMKGDKEFTGTLTGFDDYVNMVLEDVIEFDKILLNGNGIAMLVPGGEGP Caeel ELIDKCIGSKIWVIMKNDKEIVGTLTGFDDYVNMVLEDVVEYETILLNGNHITMLVPGGEGP Canalb1 EVIDRSVGKRVRVLMTGDKEFNGKLIGFDDYVNMVLEDVTEVDKMLLNGGHIAMIVPE---- Cangl EVIDKTIDQQVHIILQSNREFSGKLVGFDEFVNVILEDPIEYTRMLLSGNNITMLVPGGKKL Capow ELIDKCIGSRIHIVMKSEKELVGTLLGFDDFVNMVLEDVTEFEQILLNGNNICLLVPGGEGP Catan2 ELIDKTIGSQIRVIMKSQVEFVGTLIGFDEFVNMVLENVTEYTQILLNGGSVAMLVPNGSRP Cioin ELVDKCIGSKIHIIMKSEKEIVGTLLGFDDFVNMVLEDVTEYEQILLNGNNITMLVPGGEGP CocheC53 ELIDKCVGSQIWVIMNGGKEFTGKLVGFDDYVNMVLENVTEIDKILLNGNNICMMVPGGDGQ Coere1 ELIDKCVGSRIWVLMKSDKEFVGTLLGFDDFVNMVLEDVTEFEQILLNGNNICMLVPGGEGP Conco1 EIIDKCIGSKIRIIMRDNKEFIGTLQGFDDFVNMVLEDVTEYNKILLSGNSICMLIPDVN-- Conpu1 ELIDRCIGSKIWVVMKGDREFSGTLLGFDDFVNMVLEDVTEFEQTLLNGNNICMLIPGSSGP Copci ELIDRCIGSKIWVVMKNDREFTGTLLGFDDFVNMVLEDVTEFEQTLLNGNNICMLIPGSDGP Croqu1 ELIDRCIGSRIWVVMKTGREFTGKLLGFDDYVNMVLEDVTEYEQTLLNGNQI--LVPGGSGP CryneH991 ELVDRCIGSPIWVLMKNEREFTGTLMGFDDYVNMVLKDVKE--------------------- Crypa2 ELVDKCVGSRIWVIMKGDREFSGTLLGFDDYVNIVLEDVTEFDKILLNGNNICMLIPGGEGP Debha1 EIIDKSIGHKIQVLMTNDKEFKGTLIGFDDYVNMVLENVEEFDKMLLNGSQVAMLIPSL--- Dekbr2 ELIDKSIGTKIWAIMSDFHEFVGTLEGFDDFVNIVLSDVTEYDKMLLSSRNLAMLVPGGDGP Dicdi ELIEKCIGSRIWIAMKNDKEFVGTLLGFDAYVNIFLKDVTEYENILLNGNHVCLLVPGGEGP Dmel ELVDKCIGSRIHIIMKNDKEMVGTLLGFDDFVNMLLDDVTEYEQILLNGNNITMLVPGGELA Enthi QILLEWINTKVWIILKSQREFVGIMKGIDEYTNIILQDCIEYELILVSGNGIDMISKGEKTD Falba QLIDKCIGSRIWLLLHGESELVGTLCGFDQHVNMVLEDVTEIQSMLLSGNNIAMLIPGGSPS Fomme1 ELIDTCIGSRIWVIMKNDREFTGTLLGFDDFVNMVLDDVTEYQQTLLNGNNICMLIPGSSGP Fusgr1 ELIDKCVGSRIWVIMKGDKEFSGTLVGFDDYVNMVLEDVTEFDKILLNGNNICMLIPGGEGP Galma1 ELIDRCIGSKIWVIMKSEREFTGTLLGFDDYVNIVLEDVTEFEQTLLNGSNIAMLIPGSDGP Ganpr1 ELIDKCLSSRIWVLMKSEREFVGTLLGFDDYVNVVLSDVIEYEQILLNGNNICAV------- Gloin1 ELIDKCIGSKIWVIMKSEREFTGTLLGFDDYVNMVLEDVTEYEKILLNGNNITMLIPGGEGP Hisca1 ELIDKCVGSKIWVVMKGDKEFSGTLLGFDDYVNMVLEDVTEFDKILLNGNNICMLIPGGEGP Klula1 EVIDKTIGQEVTILLKDYREFFGTLVGFDDYVNVVIENAVEYLKMLLTGNNIAMLIPGGKPA Lacbi2 ELIDRCIGSRIWVIMKSDREFTGKLLGFDDFVNMVLEDVTEYEQTLLNGNNICMLIPGSVGP Lenti61 ELIDRCIGSRIWVIMKNDREFTGTLLGFDDFVNMVLEDVTEYEQTLLNGNNICMLIPGSSGP Malgl1 ELVDRCIGSSIWVVMKGQREFVGKLLGFDDYVNMVLEDAVEYEKTLLNGNNICTLIPGGQGP Mellp23 -------------------------------------------------------------- Mnele ELVDKCIGSRMHMTMKNDREIVGVLLGFDDFVNMVLEDVTEYEQILLHGSNITMMVPGGEGP Monbr ELVDKCIGSRIHVIMKNDKELVGTLLGFDDFVNMVLEDVKEYVKILLNGSNIAILVPGSDGP Morel2 ELIDSCIGSKIWVVMKSEKEFTGTLKYFDDYVNMVLEDVTEFEQILLNGNNICMLIPGGDGP Mucci2 ELIDKCIGSKIWVVMKNEKEFTGKLCGFDDYVNMVLEDVTEYEQLLLNGNNICTLIPGGAGP Mydma ELIDKCIGSKIHIIMKTDREIVGTFLGFDDFVNVVLEDVTEFEQILLNGNNITMLVPGGQGP Neucr2 ELIDKCVGSRIWVVMKGDKEFAGTLVGFDDYVNMVLEDVTEFDKILLNGNNICMLIPGGEGP Orpsp11 -------------------------------------------------------------- Pench1 ELIDKCVGSRIWVVMKGDKEFSGTLLGFDDYVNMVMEDVTEFDKLLLNGNNICMLIPGGEGP Phybl2 ELIDKCIGSQIWVVMKNDKEFTGKLLGFDDFVNMVLEDVTEYEQILLNGNNICALIPGGAGP Picst3 EIIDKSIGHEIRVLMTNDKEFTGKLVGFDDFVNMVLEDVREIDKMLLNGGQVAMIIPA---- Plicr1 ELIDRCIGSRIWVIMKSDREFTGTLLGFDDFVNMVLEDVTEFEQTLLNGNNICMLIPGSAGP Polpo ELIEKCIGSRIWICMKNDKEFVGTLLGFDTYVNIFLKDVTEYETILLNGNHVCLLVPGGEGP Pucgr2 ELIDRCIGSRIWVIMKTGREFTGKLLGFDDYVNMVLEDVTEFEQTLLNGNQICMLVPGGNGP Punst1 ELIDRCIGSRIWVIMKNDREFTGTLLGFDDFVNMVLDDVTEFEQTLLNGNNICMLIPGSSGP Rhior3 -------------------------------------------------------------- Rhoto1 ELVDRAIGSKVWVIMKTEREFTGTLVGFDDYVNMVLEDVTEYEQTLLNGNNIAMIVPG-RGP Rozal11 -------------------------------------------------------------- Sacce1 EVIDKTINQKVLIVLQSNREFEGTLVGFDDFVNVILEDAVEWLRMLLSGNNIAILVPGGKKT Salro ELIDKCIGSRIHVVMKSDKELVGWLKGFDEFVNMVLTDVTEFEEILLSGTHIAMLVPGGEGP Schco3 ELIDRCIGSRIWVVMKNDHEFTGTLLGFDDFVNMVLEDVTEYEQTLLNGNNICILIPGSAGP Schpo1 ELIDKCIGSNLWVIMKSEREFAGTLVGFDDYVNIVLKDVTEYDEMLLNGNGMCMLIPGGK-P Sorma -------------------------------------------------------------- Sphar -------------------------------------------------------------- Spipu1 ELVDRCIGSRIWVVMKSEKEFAGTLLGFDDFVNMVLEDVTEYEQILLNGNNICMFIPGGEPP Sporo1 -------------------------------------------------------------- Stehi1 ELIDRCIGSRIWVIMKNEREFTGTLLGFDDFVNMVLEDVTEFEQTLLNGNNICMLVPGSNGP Tapde11 -------------------------------------------------------------- Thetr -------------------------------------------------------------- Treme1 ELVDRCIGSPIHVIMKNEREFTGTLMGFDDYVNMVLRDVKEYQQTLLNGNNIVMLIPGGRGP Trire2 ELIDKCVGSRIWVIMKGDKEFSGTLLGFDDYVNMVLEDVTEFDKILLNGNNICMLIPGGEGP Umbra1 ELIDKCTGSNIWVVMKGEKEFTGRLLGFDDYVNMVLEDVTEYEQILLNGNNICMLVPGGEGP Ustma22 ELIDKCIGSSIWVIMKTDREFSGTLLGFDDYVNMVLEDVTEYEQTLLNGNNICMLIPGSEGP Walse1 ELIDKCIGSRIWVIMKNEREFVGTLQGFDDFVNMVLDDVTEYDQTLLNGNNVCMLLPGGEGP Zygro1 EIIDKTVGQPVWIVLQSNREFTGTLIGFDDFVNVIVEDAKEVTRMLLSGNSIAMLVPGNKRP [Cluster2304.fasta_al_trimmed; alignment length = 368] Allma1 NPATRQEITDLADLRKRLGSRIEFGTAGLRARMEAGFSRMNDLTVIQATQGLVAYLSVVLGHDHRLSSARFTRLTAAVFLHKGIKVYVHTPMVPFGVKALATCGIMMTASHNPKADNGYKLYWNNGCQIIPPVDAGIAAAILDNLICYTAMHGVGLPFPDPDFPTVAFPNPEEGKGALELACRAADLHQVILANDPDADRLAVAEKFWHIFSGNQIGIMLALGCLTTTVSSMMIKQMAHDEGVEFEETLTG--FKWLGNRAIAMQEGRADKVFFAFEQAIG-FMVRDKDGVSAGVCVA-ELTLVEFLQSLYVKYGFFASNDGYVIEPDPKRVDAMFVRDV-TVGYGAHMLTTLRTSGTEP-KVKYYTE Ashgo11 NSETQHEICELDELRKRLLPRITFGTAGLRARMEAGFSRMNTLTVIQASQGLARYIKVVIGHDHRFHSREFAEATIAAFLQLDYDIYVHTPMVPFAINNVTSCGVMITASHNPKMDNGYKVYYANGCQIIPPHDELIGRHIDANLFVYTPMHGVGYEFPDPEFPTVSFPNPEE-RGALDMAMKVADANGVVLANDPDADRFSVAVKEWNQLTGNQIGILFALAMLTSAVSSQLLRKMAEEEGFLAVETLTG--FKWLGNRARELLE--GYYVPFAYEEAIG-YMVHDKDGIAAAAVFL-QMSSQEVLQECYEKYGYFVDYNGYYISSAPAVTKEVFLRDL-TVGYNSQMITTARGSGTEP-KLKVYIE Aspfu1 NPETRAEIEQLAELELRLRQRIQFGTAGLRGRMAAGFSCMNSLTVIQASQGLAKYIGVVIGHDARHNSAKFAALAANAFIAMGIPVWTLTPSVPFGVTHVAAAGVMITASHQMDDADWWTRYFKNGAQINTPMDVEIAQSIDNNLFMYTPLHGVGGLIPNPDFPTVAFPNPEE-NGSLDLAMQSADKEGLIIANDPDADRFAAAEKSWFTFTGNHLGVLLAIAVLNSAVSTGMLEKMARSKGFHFEETLTG--FKWMGNIARRLES--GYHVPFAFEEALG-YMCHDKDGVTAAMVFL-AATPYSKLQQLFKDFGYFETLNNYFRSPSPEITKSLFWRDM-TEGYSSQMLTTIRGSGTEP-KVKVYIE Aurde31 NETTREHIRDLEELEGLMRPRLEFGTAGLRGPMRAGWAGLNDLMVVQTCQGIGQYAGVVIGYDHRHNSQRWAEMAAESFVLQGFKVYSFTPLVPFAVTHLTAIGCMITASHNPGGDNGIKIYWDNGVQIVAPHDEGIAAAIIRSLVVHTSLHGVAEPFPDPDFPTTVYPNPEE-KGALNCAMAYADKLGYIFANDPDADRFCVAEKKWRILTGNELGVILASCMITTVVSSKMLQSIAASEGLGYAECLTG--FKNIGNLALAKAQ--GFACYFGYEEALG-YAIKDKDGISAALIFA-QLTLHSFLESLYTRYGYFASSNSSIRC-NQASINSIFIVDM-TIGYPGQMVQTIRASGTEP-KVKYYLE Batde5 NPVTHAEIKGLDKLQKLLSTRIAFGTAGLRAEMGGGYSRMNELTVIQASQGVCAYYGVVIGHDHRHNSDAFARLTAAVFASKGIKVYVHTPMVPFGVTSLAGCGIMITASHNPKQDNGYKLYAGNGCQIISPHDSLIAEQILLNLFCYTAMHGVGLTPPDPEFPTVAYPNPEEGKGALTLAMQTADKNGVIFANDPDADRLAIAEKEWHIFNGNEIGVILALAMLTTTVSMHMLKQVAKQEGFQFEETLTG--FKWLGNRAIDLKK--GFQVAFAYEEAIG-FMVRDKDGVSALGVVA-EWTLHGYLLSLYEKYGYFTSNNGYFICHEQSVINSLFVRDL-TIGYSAQMLTTLRTSGTEP-KIKYYTE Botbo1 NPTTREEIERLAQLEKRLRNRIEFGTAGLRGRMEAGFARMNDLIVIQASQGLCSYVGVVVGHDHRHNSERFAKLTAAAFINRGVRVYVHTPLVPFSVSKLAACGVMVTASHNPKNDNGYKVYWENAVQIIAPHDEGIAASIKANLFVHTAMHGVGHTFPDPEFPTVTFPNPEE-KG-MDLAIREADTMGYVLAQDPDADRFAAAEKTWRIFSGDQLGALLALAMVASTVSSKMIESMARTEGFRFAESLTG--FKYIGNTALALKE--GYEVPFGYEEAIG-FMLRDKDGISTMVSFA-ELSLVSYLDELYNRYGYFQTSNSYFVCEDPTITDRIFVRDL-TVGYAGHMITTIRTSGTEP-KIKYYLE Botci1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel NDKNRNEIQKLDALKARMDTRLVFGTAGVRSPMQAGFGRLNDLTIIQITHGFARHMGVAIGFDGRYNSRRFAELSANVFVRNNIPVYSPTPVVSWATIKLCDAGLIITASHNPKEDNGYKAYWSNGAQIIGPHDTEIVRIKEAEPFTYSAFHGIGYHYPNPDFPTIPFPNPEEGRKVLTLAMETADKNGVILANDPDADRIQMAEKEWRVFTGNEMGALITVYILNSAVSSQIVKTIADAEGFKNETTLTG--FKWMGNRAEELAD--GNQVILAWEESIG-YM-MDKDGVSAAAVFA-EISLQDQLYALYNRYGFHLVRSTYWMVPAPEVTKKLFVRDL-TIGYSSEMVTTLRASGTEP-KIKYYIE Canalb1 NPESRHEIEQLEQLDRKLSKRIAFGTAGLRSSMESGFSHMNDVTVLQASQGLVKYLSIVIGYDHRFNSQRFAEILASVALTQGVHVYVHTPLVPFAIDYYASGGVMITASHNPANDNGYKVYYSNGCQIIPPVDKEIADSIEENLFVYTPMHGVGYRIPDPTFRTVSFPNPEE-KGALDLAIETARKLGLVLANDPDADRFSVAVEQWNQLTGNEIGFLFAVYLVNSTVSSQILKAMADKDGFHFQDTLTG--FKWIGNKAIDLKE--GFKVPFGYEEAIG-FMVHDKDGISAATIFL-QLDVTDKLEAGYAKYGWFKDYNGYYRLADMSTLDKIFWRDL-TIGYSSQMITTCRGSGTEP-KLKLYIE Cangl NEETRNEVIKLDELHKRFDSRIVFGTAGLRARMEAGTNRLNKLVILQASQGLATYITAVVGHDHRYHSQEFAQVTAATFIRAGFKVYVHTPMVPYSVDHLASVGVMITASHNPKMDNGYKVYYTNGCQIIPPHDHGIAETINNNLFVYTPMHGVGHQIPDPSFRTVSFPNPEE-KGALNLAITLAEANGLVLANDPNADRFSVAVREWKQLTGNEIGLLFALAMLNSTVSAQVIKRMAEKEGFLYKDTLTG--FKWIGNEAAKLEK--GYFVPFGYEEAIG-YMEHDKDGVSAAIVFL-QANPIDIIHECYDKYGVSAEYNGYYIVSDPSKTDKVFFRDL-TIGFNSQMITTIRGSGTEP-KLKVYIE Capow NPKTRKEITDLAELHTRLDARMEFGTAGLRAAMAAGYSRMNDVTIIQTAQGFARYVGVAIGYDARHNSQRWAQLSALALVARGIKVYCPTPFVPFAVCKYTAAGVMVTASHNPKNDNGYKVYWGNGAQIISPHDKGIASHIEENLITYTAMHGVGLEFPDPEFPTVKFPNPEEGKSALDLSIRTANANDVIVANDPDADRLAVAERSWKIFTGNEIATIFAAACVASTVSSKFLKRMAEVEGCYFEETLTG--FKWIGNKVIELAA--GRDIIMSFEEAIG-FSVFDKDGVCASAVMG-LITLMQQLEALYLKYGYFASLNSYYLCYSQPTIQKIFVRDL-TTGYSSQMVTTIRTSGTEP-KIKYYTE Catan2 NPATRKEIEDLAELAKRLSSRIEFGTAGLRAEMCAGFSRMNDLTVIQATQGLVQYVSVVLGFDHRLTSARFARLTAGVFLSKGIKVYVHTPMVPFGITHLASCGIMITASHNPKADNGYKLYWGNGSQIVPPMDAHIAQSIEDNLICYTAMHGVGFPWPDPEFPTVAFPNPEEGQGALSLAMAAADSHGIILANDPDADRLAVAEKQWHIFTGNQIGIMLAFAVLTTTVSSMMIKQFAKVEGLAFEETLTG--FKYLGNCGMAMDRGDADLVMFAFEQAIG-FMVMDKDGVSAGVCLG-ELTLFEWLQHLYVKYGFFASNDHYVVEHDKKKVDAMFVRDC-TAGWAAHMITTLRTSGTEP-KVKYYTE Cioin NEKTRNEIIQLDNLKKYLLKRMEFGTAGLRAEMGAGNSRMNDLTVIQTTQGFCKYLGVIIGYDSRHNSSRFARLAANVFGLQGVKVYVPTPFVPYGVLRYTCAGIMVTASHNPKQDNGYKVYWENGSQIIPPHDSGIAECISASLFTYTPVHGVGLAFPDPEFSTVKYPNPEEGKGVLLLAMRTADETGVILANDPDADRLAIAEKSWKVFSGNELGSLIGIYMLSSTVSSMILQAIAEKEGFKFEDTLTG--FKWMGNRTDQLKE--GKTVLFAFEEAIG-YMVLDKDGISAMSVVA-ECTLTQQLQNIYNTYGDHVSSNSYYICHDPSKIEAMFIRDL-TTGFSSHMITTIRTSGTEP-KIKYYSE CocheC53 DKTTTDEIYKLDELERRLRHRIAFGTAGLRGPMQGGFACMNSLTVIQASQGLAAYLGVVIGRDARHNSEKFAKLTAAAFVAKGIKVWSHTPMVPFGVRELAAAGIMITASHNPAKDNGYKVYWSNGCQIIPPHDSGIAQAILENLFVYTPMHGVGLPAPDPDFPTVKFPNPEE-KGALDLAIETAEKSSLILASDPDADRLAAAEKKWHIFTGNQLGVLLGLAMLASTVSSRMLAALAKKEGFHFTETL----------------------------------------------------------------------------------------------------------------------- Coere1 GPKSRAQIETLQALEELLRNPVEFGTAGLRARMEAGYSRLNQLTVISASQGLAAYVGVVIGHDHRHNSSIFARLTARAFVDRGFRVHGFTPQVPFAVKHLAACGVMITASHNPKDDNGYKVYWENGAQIKPPLDEGIADSIDKHRYVYTAMHGVGAPFPDPNFPTVTFPNPEE-KGALDMAKTLADEHGLVLANDPDADRFAAAEKTWITFTGDQLGIIFALAMVNSTVSSRMLEAMSAKEGFHYLDTLTG--FKWMANELASLNQ--GYYVGLGYEEAIG-YMVLDKDGVSALAVFA-QLRISDYLQSLYAKYGYFVSANSYFLCPDTAKMDRIFIRDL-TEGFSSHMLTTMRTSGTEP-KLKYYLE Conco1 DQESVNYIDKLLELDNLLTNPIKFGTAGLRAKMEPGFSRMNNLTVLQASQGLCAYAGVVIGYDHRYNSETFAKLTAAPFLKKGFKVYVHTPLVPFGITELAVCGVMITASHNPKDDNGYKVYWSNGCQIIEPVDAGIANQIRLNEYLYTPLHGVGGKYHDPDFPTVKFPNPEE-KGALDLAMEEGSKIGIILANDPDADRFSAAEREWVQFNGNQLGTMIGVGMLASAVSSGMLQAIGKVEGYDFEVTLTG--FKWMGNQALKWQRDPTMKAIFAYEEAIG-FMVRDKDGISAMITFV-NLTVYEYLMGLYHKYGCFVNENSYYICRDPELINTIFIRDL-TIGHSSQMITTLRTSGTEP-KIKYYSE Conpu1 NGQTRAEIEILQELESRLRNRIEFGTAGLRGRMEAGWARMNDLIIIQASQGLCAYVGVVMGHDHRHNSARWAQLAAAAFISQGVKVYVHTPLVPFSVKALAACGVMITASHNPKDDNGYKVYWENAVQIIEPHDKGIATSIKENLFVNTSMHGVGYPFPDPDFPTVAFPNPEE-KGALDLAISTANEQGYVLAQDPDADRFSAAEKTWKVFTGDQLGTLFALAMVASTVSSKMIETMANDEGFRFVECLTG--FKFIGNTALDLAQ--GYDVPFGYEEAIG-FMIRDKDGVAATMMFA-ELTLQDYLEEQYDRYGYFETNNSYFICSDPAVIDKVFVVDL-TSGYSGHMIQTIRTSGTEP-KIKYYLE Copci NPETRTEVERLDELNRRMSTRIEFGTAGLRGRMEAGWARMNDLTVIQASQGLAEYVGVVVGYDHRYHSKRWASLTAAIFVQRGFKAYVHTPLVPFGVKYLAACGVMITASHNPKQDNGYKVYWENAVQIISPHDEGIAKSIDQNLPINTSMHGVSDPFPDPEFPTVKFPNPEE-KGALDLAIATADRESYILAQDPDSDRFSAAEKKWHIFTGDQLGTLFAIAMVASTVSSKMLESMAEIEGFKFVECLTG--FKYIGNTALDLRE--GYEVPFGYEEAIG-FMIRDKDGVAATVIFV-DLTVFEYLDTLYAKYGHFKSNNGYFVCQEPAKIDAIFVVDL-TLGYSGHMLQTTRTSGTEP-KIKFYME Croqu1 NLTTRAQIEELQELKERLSKRISFGTAGLRAEMCAGFARMNDLTVIQATQGLAAYLGVVIGHDHRHNSQRFAHLTAVAFIRREIKCYIATPIVPFGTKFLAAAGVMVTASHNPASDNGYKLYYSNAVQIIPPHDTGIAAAIEQNLFIYTPMHGVGLPFPDPDFPSVKFPNPEE-KGALDLAMRLGEEIYVLLANDPDADRFCAGEWKWHVFSGDEIGSILGLAMLASTPSSKLLAAVAAKEGFKFKETLTG--FKYLGNAALELKE--SYTVPFAYEEALG-YMLRDKDGITALSLWA-ELSLVEYLESIYQRYGYFATNNGYFACKDASKVDQAFIRDL-TIGYGSQMVTTLRTSGTETWKLKYYVE CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 NPKSRKEIIELSKLNEKLSKRIAFGTAGLRSTMTSGFAHMNDVTILQASQGLIKYLSIVVGYDHRFHSQRFAEITASVALTQGFKVYVHTPLVPFAIDYFASAGVMVTASHNPAQDNGYKVYYGNGCQIIPPNDSGIANSIERNLFTYTPMHGVGMEIPDPEFLTVKFPNPEE-KGALALSIKNANELGLVIANDPDADRFSVAIKEWVQLTGNEIGFLFATYLINSTVSSQVLASMAQHHGFKFIDTLTG--FKWIGNKAIDLKE--GFNVPFGYEEAIG-FMANDKDGISALVIWL-QLDPVDKLNEGYEKYGWYKEANGYYKLNDLSMTQKIFWRDL-TLGYTSQMITTCRGSGTEP-KLKIYIE Dekbr2 DPVTRAEIQKLEELDKRSSNRIVFGTAGLRSRMEAGFSRINDVTILQASQGLAKYISVVIGHDHRHHSERYADLAAAAFLHYGFKVYIATPVVPFSVDHFASAGVMITSSHNPKDDNGYKVYWKNGCQIIPPHDKGIQKSIIHNLAVYTPMHGVGYE-PDPDFPTVSFPNPEE-KGALDLAISTAEKAGLVVANDPDADRFSVAVKVWKQLTGNEIGFLFAVYMVNSTVSSQMIASVAEKMGFHHEETLTG--FKWIGNKAIDLKE--GFSVPFGFEEAIG-FMSHDKDGISALAVFL-QMSISSVLNQGYKKFGFYSSCNGYYRTTDKSIIPKIFWRDL-TVGFSSQMITTARGSGTEP-KLKVYIE Dicdi NEITRKEIEQLKELLVRLEERIQFGTAGLRGAMRAGFSCMNDLTVTQASQGLCEYVGIVIGYDGRHNSYIFAKITAATFKSKGFKVYVPTPYVSFAVPNLAAIGVMITASHNPKNDNGYKVYWETGCQINTPHDKGISKKIDENLIVYTAMHGVGGVYPDAEFPTVTYPNPEEGKGALKLSIETAEANNLILANDPDADRLAVAEKSWKVFNGNEIGVLLAYFMINTAVSSAMLKTMSEKEGFIHQECLTG--FKWIGNAAYNANNNDGTTFLFGYEEAIG-FQSFDKDGVRAAAIFA-EFSVQDHLESMYKRYGYHISKNRYFFCYEPSKMVSIFIRDL-TTGYSTQMITTLRGSGTEP-KLKYYVE Dmel CASTACQIMDADTLRKRLCTRISFGTAGLRACMRAGFDSMNELVVIQTAQGLCEYIGIVFGYDGRYNSHRFAELSAIVFLNNDFKVWVATPMVPFAILRLCLAGVMVTASHNPKEDNGYKVYWTNGAQIIPPHDEGIQESILNNLFTYTAMHGVGYAFPDPEFPTTPMPNPEEGKTSLDLSIKTAKANSIILANDPDADRLAVAEVSYKLFSGNEVGALLGCVMIASTVSSKILRAMAEREGFQFFETLTG--FKWMGNKAIELQA--GKTVLFAFEEAIG-FMVLDKDGVSAAGHLA-TMTLQEKLRDIYETYGFHTTVSSYVICRCPPVIEQIFVRDL-TTGFSSQMITTLRTSGTEP-KMKYYAE Enthi TPETRKEIEDLEELKKRFCKRIEFGTAGLRGKMCAGFNCMNNLIVQQASQGLALAVGVVIGYDGRYHSKEFAAITAKVFISKGFKTYCPTPWTAFAVGYLTACGVMVTASHNPKADNGYKVYWENGCQIIEPIDANIASKIHSNLYVYTAMHGVGSKYPDPEFPTVPFPNPEEGKGALKCSIEVAEANGVIIANDPDADRLSVAVK-WRQFTGNEMANLIA-FMVRSTVSSSFISKMGEVEGFDTYETLTG--FKWIGNKAKEIDT-QHKKLLMAYEEAIG-FVSYDKDGVRAAVCFA-AMNLEDRLNMLYEKYGYFASNNKYYFCYDPKLMEKIFIRDL-TVGISTQMITTLRGSGTEP-KLKYYIE Falba CPATRDEIADLAKLDQLLTTRVSFGTAGLRASVGAGFSRLNDLVIIQTTQGYLRYLGVVIGHDHRHGSLSFAHLSAGVFLRENIPVHVHTPMVPFAVRHLAAAGIMITASHNPKQDNGYKVYSSIGTQIVAPADEKITEFILSDLIVYTALHGVGQRYPNPDFPTVQYPNPEEGKGTLQMAIDLANSTGVILANDPDADRLGVAVRAWRLLTGNEIGLLLAVAMLTTAVSSGILHKVALHHGFLSETTLTG--FKWLGNRTIELAS--GYHVLFAYEEAIG-YMLPEKDGISAAVVFA-ELTLLSELRRLESLYGVVVNRNSYLFSPSPATTKSIFVRDV-SLGVSAMMITTLRASGTEP-KLKYYSE Fomme1 NENTVAEIKNLKELRSRMSKRIEFGTAGLRGRMEAGWARMNDLIVIQASQGLCAYVGIVIGHDHRHHSKEWAKLVAMVFLNKGFKVYVHTPLVPFTVSELAACGVMITASHNPKEDNGYKVYWENAVQIISPHDTGIAKAIEENLFVNTSMHGVGHVYPDPEFPTVSFPNPEE-KGALDLALKTADGIDYVLAQDPDADRFSAAEKKWITFTGDQLGAILALAMVASTVSSKIVEAMALKEGFKFAETLTGTSFKYIGNKAQDLKE--GYSVLFGYEEAIG-FMIRDKDGISATAVFA-ELSVSTYLQDLYRKYGHFETANSYFICKDPPTIDRIFIRDL-TVGYSGHMIQTIRTSGTEP-KIKFYLE Fusgr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 NPETRNEIQTLDELEKRLRTRIDFGTAGLRGRMEAGWSRMNDLIILQTSQGLSEYIGLVVGYDHRHHSEHWAILTANIFVAKGIKVYNHTPMVPFAVKKLAACGVMITASHNPKQDNGYKVYWENAVQIVPPHDKGISIAIQTNLFVNTSMHGVGDYFPDPEFSTVPFPNPEE-KGALDLAIETAEREGYVLAQDPDADRFTAAQKEWILFTGDQLGSIFALAMVASTVSSKMIETMAEVEGFKFVECLTG--FKFIGNTALRLAD--GFTVPLGYEEAIG-FMIRDKDGVAATMIFA-ELTVNDYLQELYQRYGYFQTKNSYFICNDPKVTDEIFIIDL-TTGYSGHMVQTLRTSGTEP-KIKIYLE Ganpr1 NASNRGYIQKLKSLESLLRNRLQFGTAGLRAAMGPGYSRMNDLTVIQASQGLASYLTVVIGHDHRHGSFRFARLSAACFLFRGFRVLVHTPMVPFVVKKQASAGIMITASHNPAADNGYKLYAANACQIVAPVDSHVSKYILENLITYTPMHGVGSPYPDPDFPTVAYPNPEEGKGALKLAMEVADRSTYIVANDPDADRLAVAEKDWVVYSGNQIGCILAPAFLATAVSSRLLSQLCQVEGVEYHETLTG--FKWIGNRVVELAE--GREVVFAYEEAIG-FMVRDKDGVSALATFA-ELGAGDYLDGLYAKYGDFVSKTSYFVCHDPIKMTKICIRDL-TEPYSTQMITTLRTSGTEP-KLKYYVE Gloin1 NPTTRSEIEKLDELEKRLRNRISFGTAGLRSNMEAGFSRMNDLTVIQASQGLCMYLGVVIGHDHRHNSERFARLTAAIFITKGFTVYVHTPLVPFGVKRLASCGIMITASHNPKQDNGYKVYLENGCQIISPHDKGIAKSILKYLFVYTAMHGVGTQVPDPDFPTVAFPNPEEGKGALALAIKTADENGIIFANDPDADRFSVSEKEWNIFSGNQIGIILALAMLASTVSSKMLEKMAKVEGFYFEETLTG--FKWLGNKAIDLQQ--GYEVLFAYEEAIG-FMVKDKDGVSALVTFA-ELTVSEYLEELYNKYGYFVSDNSYFICYSPQTIDKIFIRDL-TIGYSSHMITTLRTSGTEP-KIKYYLE Hisca1 DPETRAEIIRLVELEKRLRKRIEFGTAGLRGRMQAGFSSMNALTVIQASQGLAKFISVIIGRDARHNSKKFAMLAANAFAAEGIRVLGPTPLVPFGVLKNEAWGVMVTASHNPARDNGYKVYASNGCQINSPMDAEIADLIEQNLFVYTPLHGVGHSLPDPDFPTVAFPNPEE-SGALDLAMKTADAVGLVIANDPDADRLAVAEKNWIKFTGDQLGILLAIAMLTTAVSTSMLSKIARAESIHAQETLTG--FKWLGNVARRLSD--GYTVPFGFEEALG-YMSYDKDGLTAAMVFVAAATPYEKLKQLYGRYGYFENLNTYFVSPDVAVTRKLFWRDV-TFGFNNQMVTTLRGSGTEP-KIKIYIE Klula1 VEETRNEILQLTELHKRLDTMIAFGTAGLRGRMEAGFNRMNALTVKQASQGLAKYITVVVGHDHRHNSRLFGKVTVDTFLQLGFKVFVHTPLVPFTVNATASVGIMITASHNPKMDNGYKVYYTNGCQIIPPHDKLIAESIIHNLFVYTPMHGVGFEIPDADFPTVSFPNPEE-KGALDLAVEYGRKNDLIIANDPDADRFSVAVRAWRQLTGNEIGFLFALAMLNSTVSSQMIKRMAEIEGFHYEDTLTG--FKWLGNRALELQE--GYYTPFAYEEAIG-YMVHDKDGISAAIVFL-QATVLDILATASLKYGHFKEFNGYYIVPDLAITKQVFFRDL-TNGYSSQMITTIRGSGTEP-KLKVYIE Lacbi2 NPETRKEIQTLEELEKRMSPRIEFGTAGLRGKMEAGWSRMNDLIILQASQGLCAYVGLVIGHDHRHNSDRWARLTAAAFIEAGMRVHVPTPLVPFSVKRLAACGVMVTASHNPKQDNGYKVYWENAVQIIAPHDQGISESIKANLFVNTSMHGVSDPFPDPEFTTVRFPNPEE-KGALDLALATADKEGYVLAQDPDSDRFSAAEKEWINFTGDQLGILFALAMVASTVSSKMIEAMAKREDFKFVECLTG--FKYIGNTALDLKE--GYEVPFGYEEAIG-FMIRDKDGIAATLAFA-ELTAYGYLQELYKTYGYFKTSNSYFVCNNPITIDRIFVVDL-TIGYSGHMIQTIRTSGTEP-KIKYYAE Lenti61 NEETRREIEQLAELQKRMSPRIEFGTAGLRGKMEAGWARMNDLIIIQASQGLCAYVGVVVGHDHRYHSERWAKLAAAAFIDQGVPVYVHTPLVPFTVRTKAACGVMITASHNP------KVYWENAVQIIEPHDKGISASIKQQQFVNTSMHGVSDAAPDPEFPTVRFPNPEE-NGALDLAIATATQSGYILAQDPDSDRFAAAEKKWIQFTGDQLGTLLALAMVASTVSSKMIEAMARAEGFKFAECLTG--FKYIGNTALTLQE--GYEVPFGYEEAIG-FMLRDKDGVAASVVFA-ELTASSHLRELYAKYGFFQTSNSYFICTEPSTIDSIFVRDL-TIGYSGHMIQTTRTSGTEP-KIKYYLE Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 NPTTRAQIEDLEELADRLLKRISFGTAGLRAEMSAGFSRMNDLTVIQASQGLAAYLGVVVGHDHRHNSRRFAHLASLAFIRRGIKCYVATPIVPFGTKFLAAAGVMITASHNPAADNGYKLYYSNAVQIIPPHDAGIAAAIEGNLFIYTPMHGVGLPFPDPSFPSVKFPNPEE-KGALDLAMRLGEEIYILLANDPDADRFCAAEWQWHVFSGDEIGSILGLAMLASTPSSKLLATVAIQEGFKFKETLTG--FKYLGNATLELLE--GFKVPFAYEEALG-YMLRDKDGITALAIWA-ELSLTQYLDSIYQRYGYFATNNGYFTCKDPSKVDQAFIRDL-TIGYSSQMITTLRTSGTELWKLKYYVE Mnele NENTCAEILKMSELEAMLTNRMAFGTAGLRARMGPGYACMNDVTVIQTSQGFGKYLGIAIGFDARHNSARFAKLAAVAMIRLGIPVHTPTPLLAYSVRKYTAAGIMITASHNPKDDNGYKVFWSNGAQIIPPHDRNIAQHILENLLTYTPMHGVGQKFPDPDFPTVIFPNPEEGKSALDLAMKAADANGVIIANDPDADRLACAERSWCVFNGNELGSMLGLYMVASTVSSKFLKSMSQREGFLFEECLTG--FKWMANYALRKAE--GYTCLFAYEESIG-YMVMDKDGISAGPVLA-AYTLSQFLHSLYSKYGYHISNDSYYLCYDPPTIQTIFIRDV-TTGYSCQMLTTLRTSGTEP-KIKYYTE Monbr YPDTLEEAKRLEEIERRFGSRMTFGTAGLRAPMQAGWACMNDLTVIQASQGLAKHVRVVIGFDGRHNSSRFAMRAARAFKQLGAEVYVPTPFIPFAVSHLCAAGIMVTASHNPKQDNGYKVYWSNAAQIISPTDKEIAAKIEDNLITYTAMHGVGYRYPDPEFPTVEYPNPEEGKGALQLAMATAERHSLILANDPDADRLAIAVLKWHILTGNEIGSLFAVFMLASTVSSKMLQTMANVEGFQFDETLTG--FKWLGNRAIDLSA--NHEVLFSYEEAIG-FCVVDKDGVTAAAVAA-EMTLVNKLEELYALYGYHATFNSYYICHDKMIIDRIFVRDV-TMGFSGHMITTFRTSGTEP-KIKFYSE Morel2 NPETRKEIETLAELEARLRQRIEFGTAGLRAAMEAGFSRMNDLTVIQASQGLCLYVGVVIGHDHRHHSNDFARLTAGVFLSKGVKVYVHTPMVPFGVKSLAACGIMITASHNPKKDNGYKVYWENACQIIPPHDEGIAQMILDNLFVYTAMHGVGYPFPDPEFPTVAFPNPEEGKGALALAFKAADEAGVVFANDPDADRFTVAEKEWILFTGNQIGTMFAVAVLCSTVSSNMLAKVAKTEGIHWEDTLTG--FKWIGNRAIDLKE--GYNVIFGYEEAIG-FMVRDKDGVSALGTFA-QLKISEYLDSLYKKYGYFSSANSYFICHEQETIDRIFVRDL-TLGYSAQMITTLRTSGTEP-KIKYYLE Mucci2 NEETRNEIIALQELEKRLSTRIEFGTAGLRARMEAGFSRMNDLTVLQASQGLAVYIGVVVGHDHRHHSKEFAQLTAAAFIQRGFKVWVHTPLVPYTIKKLAAGGVMITASHNPKDDNGYKVYWENACQIIPPHDEGIAATILENLFVYTAMHGVGTPFPDPDFPTVAFPNPEEGKGALNLAIQTADKVNIILANDPDADRLAIAEKKWVIFTGNQIGSILGLAMVASTVSSKFLARMAEVEGFRFEESLTG--FKWIGNTAMLLKQ--RLNVIFSYEEAIG-FTVKDKDGVSALAFFS-EWTAYDYLEELYKKYGYFVSENSYFICDDKKKIAKIFIRDL-TVGYSSEMITTIRTSGTEP-KIKYYSE Mydma NESTFNEIKSLDELEKKVLTRLEFGTAGLRAAMGAGFSRMNDLTVIQTTQGLCAYLGVVIGHDARHNSHRFARLAASVFLNAGVKVYVPTPYVPFSVLKYCAAGVMVTASHNPKQDNGYKVYFSNGCQIIPPHDERISESIFANLITYTAMHGVGEKYPDPEFPTVKYPNPEEGKGALKLAIETAEANNFIIANDPDADRLAVAEKSWKIFNGNEVAFLLGIYMIYSTVSSRALRTMGEIEGFQFEETLTG--FKWMGNKTTELEK--GKTVLFAFEEAIGKYVVLDKDGISAGVIMS-ELTVAEQLEKLYEMYGIHISNNSYYICYDQATIKKIFVRDLYGIGFSGEMITTIRTSGTEP-KIKYYSE Neucr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 --------------------------------------------------------------------------------------------------------------------------------IIPPTDKGIANKIKENQFCYTAMHGVGLPFPDPDFSTVEFPNPEEGKGVLDLSIAKANATGVILANDPDADRLAIAEKKWYSFTGNQIGVILGIAMVNSTVSTKMLEKIAKVENFRFEETLTG--FKWIGNKAIDLKE--GYTVPFAFEEAIG-FMVNDKDGVSALALLA-ELNILDYLNSLYNKYGYFMSNNYYFICHEQEVINAFFIRDL-TIDYSSQMITTLRTSGTEP-KIKYYIE Pench1 DPTTRVEIEQLEELEKRLRNRIEFGTAGLRGRMSAGFSCMNSLIVIQASQGLAKFIGVVIGHDARHNSAKFAALAANAFIAQRIPVWGPTPMVAFGVNYFAAAGIMVTASHNPPQDNGYKVYSSNGAQINRPEDGEIAQSIQENLFVYTPLHGVGGLVPDPDFPTVKFPNPEE-AGALDLAIETADREGLIIANDPDADRFAVAEKKWHTLTGNHLGVLLAIAVLTTTVSSGMLGKMAAAKGIHFAETLTG--FKWMANVARDLKE--GKSVPFAYEEALG-YMCYDKDGITAAAVFL-AATAYAKLQQLFSEFGHHETLNNYFRSPNPQLTSTLFWRDL-TEGYTSQMITTFRGSGTEP-KVKFYIE Phybl2 NEETRNEIIALDELAKRLLNRIEFGTAGLRARMEAGFSRMNDLTVLQASQGLAAYIGVVVGHDHRHHSEDFARLTAAAFLTRGFKVWVHTPLVPFTIKKLAAGGVMITASHNPKDDNGYKVYWENACQIIPPHDEGIANTILENLFVYTAMHGVGLPFPDPDFPTVAFPNPEEGKGALSLAIETAEENNIIIANDPDADRLAIAEREWKLFSGNMIGSILGLAMVASTVSSKFLARMGEVEGFRFEESLTG--FKWIGNKALELKE--GYNVVFSYEEAIG-FTVKDKDGVSALAFFA-EWTVFEYLEGLYKKYGYFVSDNSYFICHDKKLIESIFVRDL-TVGYASEMITTIRTSGTEP-KIKYYSE Picst3 NPESRNEIALLAQLHLKLANRIAFGTAGLRSSMESGFAHMNDVTILQASQGLIQYLSIVVGYDHRYNSQRFAEITASVAIAKDIKVYVHTPLVPFAIDLYASGGVMVTASHNPARDNGYKVYYGNGCQIIPPHDEGIASSIEKNLFVYTPLHGVGLEIPDPDFSTVKFPNPEE-KGALDLAIKKAESLGLVLASDPDADRFSAAIKNWKQLTGNEIGFLFATYLVNSTVSSQILKSMADKNGFHFIDTLTG--FKWIGNRAIELNE--GYNVPFGYEEAIG-FMVNDKDGISAAVIWL-QLDPVDKLNEGYAKYGWFKECNGYYKLNDLSKTREIFWRDL-TVGFKSQMITTCRGSGTEP-KLKVYIE Plicr1 NEHTRNEIEGLEELERRLRKRIEFGTAGLRGRMEAGFSRMNDLIIIQASQGLCAYVGVVIGHDHRHNSERWAQLTATAFIARGVKVYVHTPLVPFSVKRLAACGVMITASHNPKQDNGYKVYWENAVQIIGPHDTGIAAAITENLFVNTSMHGVGHPFPDPEFPTVKFPNPEE-HGEYDLALRTAEQVSYVLAQDPDADRFSAAEHEWTTFTGDQLGTLFALAIVASTVSSKMIEAMADAEGFKFVECLTG--FKFIGNTALSLAQ--GYEVPFGYEEAIG-FMIRDKDGVAATVVFS-ELTLKGHLQELYQKYGYFQTSNSYFICSDPPTIDAIFVVDL-TTGYSGHMIQTTRTSGTEP-KIKYYLE Polpo NAETRKEIQSLSELKSRLEQRIAFGTAGLRGPMKAGFSCMNDLTVIQASQGLCIYVGIVVGYDGRHHSKEFARLTAATFASRGFKVYVPTPYVAFAVPELASVGVMITASHNPKDDNGYKVYWDNGCQINTPHDIRIAMQIDLNLIVYTAMHGVGGEYPDPEFPTVAFPNPEEGKGALKLSIETAERNNLILANDPDADRLAVAERQWKVFNGNEIGVLFAFCMINTAVSSSMLKTMANKDGYRHEECLTG--FKWVGNKARELDK--GYNFLFAYEEAIG-FMSLDKDGVRCAPIFA-ELSCQDHLEELYKRYGYHISKNRYFFCYDPKKMVAIFVRDL-TVGYSTQMITTLRGSGTEP-KLKYYVE Pucgr2 NPTTRKEIEQLDELASRLCQRIKFGTAGLRAHMSAGFSRMNDVTVIQASQGLAAYLGIIVGHDHRHNSHRFARLAVTAFLRRGFRCYVATPMVPFGVKYLAAAGVMVTASHNPAADNGYKLYYSNGVQIISPHDKGIAASIEQNLFIYTPMHGVGYPFPNPDFPTVKFPNPEE-KGALDMAMSL--------------------------------------------------------------------------------KE------------------------------------------------------------------------------------------------------ Punst1 NSATRAEVQALVELEKRMRTRIEFGTAGLRGKMEAGWARMNDLTVIQASQGLCAYVGVVVGHDHRHNSERWAELTATAFIAKGIKVYVHTPMVPFSVKSLAACGVMITASHNPKQDNGYKVYWENAVQIIAPHDKGIAAAILENLFVNTSMHGVSHPVPDPEFSTVRFPNPEE-KGALDLALSTADKHKYVLAQDPDADRFSAAERRWVTFTGDQLGVLFALAMVASTVSSKMVEAIAHAEGFKFVECLTG--FKFIGNTALNLAE--GYEVPFGYEEAIG-FMLRDKDGVAATLQFA-EMTASSHLKELYAKYGYFQTNNSYFLCYDPSTIDRIFVRDL-TIGYSGHMIQTTRTSGTEP-KIKYYLE Rhior3 --------------------------------MEAGFSRMNDLTVLQASQGLAVYIGVVIGHDHRHHSDDFARLTAFAFIKRGFKVWVHTPLVPYTIKKLAAGGIMITASHNPKDDNGYKVYWENACQIIPPHDEGIASTILENLFVYTAMHGVGTPFPDPDFPTVAFPNPEEGKGALTLAIETADKVNIILANDPDADRLAIAEREWIIFTGNQIGSILGIAMVASTVSSKFLARMGEVEGFKFEEALTG--FKWIGNSAMRLQE--GYSVVFSYEEAIG-FTVKDKDGVSALGFFS-EWTAYEYLQELYKKYGYFVSENSYFICDDKKKIGEIFVRDL-TVGYSSEMITTIRTSGTEP-KIKYYSE Rhoto1 NPETRAEVENLAELEKRFARRIAFGTAGLRGPMQTGPSAINDLVILQASQGLAKYAGIVVGHDHRHNSVQFARLTAGVFRRRGWRVYVHTPMVPFSVKQLAAVGVMITASHNPARDNGYKVYWSNAIQIIPPHDSGIAAAILESLFTYTAMHGVGLPFPDPDFPTVKFPNPEE-KGALDLAIAHADNVGLVLANDPDADRFCAAEKKWTIFTGDQIGALLGLAMCASTVSSKMLRSMARKEGFRFEETLTG--FKWIGNELQALDQ--GFAPWFAYEEAIG-FAIKDKDGVTALALFA-EMPLTVHLDSLYYEYGFHATLNSYFICRDSAKTNRIFLRDL-TVGYSAHMISTVRTSGTEP-KIKYYLE Rozal11 -----------------------------------------------MSLGLCAHLGVVIGHDHRHHSWDFARLATAVFLKNNVKVYCPTPFVPFSVTFLAACGIMITASHNPKEDNGYKVYWNNGCQIVSPTDKDIAKSIISNFIVYTAMHGVGYEYPDPDFPTVKYPNPEEGKGSLKLAIETAESHNIILANDPDADRLAIAAKNWQTLSGNQIGILLAIAMVTTIVSSKMLKAFCLKNEHRYEETLTG--FKYIGNEVLKLSE--GYRVPFAYEEAIG-FMVRDKDGISALSTAL-QMSVFDKLDKIYEELGYFASSNGYLIVKDRSRKTQIF-----IINY---MIY-FRTSGTEP-KVKYYSE Sacce1 NPKTIEEVTALNELHKRFDSRIQFGTAGLRSQMQAGFSRMNTLVVIQASQGLATYVVAVVGHDHRFHSKEFARATAAAFLLKGFKVHVHTPLVPFAVDKLASVGVMITASHNPKMDNGYKVYYSNGCQIIPPHDHAISDSIDANLFVYTPMHGVGFDIPDPSFPTVGFPNPEE-KGALDIGINLAEKHDLLVANDPDADRFSVAVKEWRQLTGNEIGFLFALAMLNSTVSSQMIKKMAEIEGFHYEDTLTG--FKWIGNRAILLKK--GYYVPFGFEEAIG-YMEHDKDGISASIVFL-QADPLNVLENGFKKYGVFKEYNGYYVVPNPTVTKDIFYRDL-TTGYTSQMITTIRGSGTEP-KLKVYIE Salro WGPTKEEAQELAAIESQFGKRIAFGTAGLRGPMKTGWACMNDLTVIQASQGLAKYLRVVIGHDSRHNSRRFARRAATAFLSLGAEVIVPTPMIPFAVSHHCAAGIMVTASHNPKQDNGYKVYWSNGAQIIPPHDAGIAKSIDAHSFTYTAMHGVGWKYPDPEFPTVEYPNPEEGKGALTLAIETAEANNVILANDPDADRLAVACKQWQILNGNQIGSLLGLYMVASTVSSKMLGTMAAAEGFNFVETLTG--FKWMGNKARDLQE--GKTVLFSFEEAIG-FCVVDKDGVNASAVMA-ELTLVDCLNDLYTKYGYHCTFNSYYICGEQATIDAIFVRDV-TLGTSGHMVTTLRTSGTEP-KIKFYSE Schco3 NEATRKEIEQLAQLESRLGSRIEFGTAGLRGRMEAGWSRMNDVTVIHASQGLCAYVGVVVGHDHRHNSERWAKLTAAAFVEKGVKVYVHTPLVPFTVKNRAACGVMITASHNPKQDNGYKVYWENAVQIIAPHDTGISASIEQHLFVNTSMHGVSHPFPDPEFPTVRYPNPEE-KGALDLAMKTAAEQGIILAQDPDSDRFSAIEAGWTTFTGDQLGTIFALAMVASTVSSKMVAAMAAKEGFRFTETLTG--FKFIGNAALDLKQ--GYEVPFGYEEAIG-YMTKDKDGVAATISFV-DLTVKGYLDELYEKYGYFETRNSYFICGDPKVITTIFVSDL-TVYWSGQMIQTLRTSGTEP-KIKYYLE Schpo1 DETTRNEVSQLATLKQIMHPRIGFGTSGLRAEIGAGFARMNCLTVIQASQGFAEYLGVVIGHDHRHKSNTFARLTAAVFLQKGFKTYVHTPLVPFAVKTLTAAGVMITASHNPAAYNGYKVYWGNGCAIIPPHDKGIAACIEKNLFVYTPIHGVGLPFPNPDFPTVKFPNPEE-EGALDLAYEQADANGYVLATDPDADRFAFAEKAWRRFTGDEVGCILAFYVLSTTVSSAMVKSMAKVEGFHHVETLTG--FKWLGNKALELKQ--GKFIGLAYEEALG-YMVRDKDGVNALITFL-HLSITEVFEQMSKKYGYYTTQNSYFLSRDTPKLRALVVRDL-TTGYSSDNVTTIRTSGTEP-KLKFYIC Sorma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar SEWTRKELNDRAGLESIMLEHMEFGTAGLRARMGAGYACMNDLTVLQAAQGLCRYLGVVVGHDHRHHSSDFAKITAAVFMSQNIPVHACTPMVPFGVIKFAAAGVMVTASHNPKDDNGYKVYWSNGAQIIPPHDSGIAGHILKNQITYTAMHGVGTPFPDPEFPTVAFPNPEEGKSALNLSMAEADRSGLILANDPDADRLAVAEKEWKVFNGNETACLLSYAMVASTVSSKYLAAMAKKEGFTFEDTLTG--FKWIGNRAIRFQE--GKKVLFGYEEAIG-FMPPDKDGVHAAAVFG-EMKLSEQLDALYVKYGYFISKDSYFKCSSQDTINALFIRDC-TTGFDIQMITTMRTSGTEP-KIKYYSE Spipu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 NATTRAEIEKLAELRSRFSHRIAFGTAGLRGPMQAGISSMNDLTILQASTGLEKYAGFVVGHDHRHNSERFAKLTAGVFRRNGWKVYVHTPMVPFATKQLAAVGVMITASHNPAKDNGYKVYWSNAVQIIPPHDHGIASAILESLFTYTAMHGVGLPFPDPNFSTVKFPNPEE-KGALNLAIEHAEKVGIVLANDPDADRFCAAEQKWNVFTGDQIGSLLGLAMCASTVSSKMLRSMAEKEGFVFRETLTG--FKWIGNEMIKLQE--GYNPMFAYEEAIG-YMIRDKDGVTALAIFS-ELTISQRLDSLYEQYGYHATSNSYFICRDPRKTDRIFIRDL-TIGYSSHMISTIRTSGTEP-KVCLSLP Stehi1 NPKTRREIEILDELESRLRTRIEFGTAGLRGRMEAGWARMNDLIIIQASQGLCSYVGIVIGHDHRHHSSRWAKLTAAAFVEQGVKVYVHTPMVPFGVKQLAACGVMITASHNPKDDNGYKVYWENAVQIIGPHDKGIAAAIRDNLFVNTSMHGVGHYFPDPDFPTVKFPNPEE-KGALDLAIATASRNDYVLAQDPDADRFSAAER-WKIFTGDQLGTIFALAMVASTVSSKMIEKMAELEGFRFVECLTG--FKFIGNTALDLKE--GYEVPFGYEEAIG-FMIRDKDGVAASVYFA-QITAMSYLRELYDRYGHFQTKNSYFICRQPPVIDRIFVCDL-TIGYSGHMIQTTRTSGTEP-KIKYYLE Tapde11 TEADKKQIQDLIELRKRMLPRITFGTSGLRSKMEAGYARMNDLTVFQASEGLRDYIGIVVGHDHRFNSQRFAQIVQAVF-APSMKVFVHTPLVPFAVKTLAACGVMITASHNPKQDNGYKVYGENSCAIIPPHDRLISEAIEAAIFCYTPMHGVGLIYPDPEFSTVKFPNPEE-AGALDLAMQTADEEGIIVATDPDADRLGVAEKKWRILTGNQIGTLLARAMLSSTVSSKILQAIGEKEGIHWEETLTG--FKWLGNRALSLEA--GYNVILAYEEALG-FLVYDKDGILSMAVLL-NFTLSDELTRLYRTYGYFQSSNSYFIVPDPPLLARIMVRDL-TRGYSSEMITTIRGSGTEP-KLKYYIE Thetr DTKRADEMAALEAVARAMVPRIAFGTSGLRAKMAAGAAHMNTLVVLQTTQGVLRVMAVFIAYDGRHESYHYAKTAAGVFLAAGISVLMATPFASYSIAHPPLVGIVVTASHNPASDNGYKVYWDNGAAILPPLATTISDAITRDLVVYTAMHGVGTPFADPDFSTVTFPNPEEGKGALKLAIETANRVGLVLANDPDADRLAVAEREFYIFNGNELGLLFAHVFINTVVSSSALMAFAKSVGAEYASTLTG--FKYMGNKAIELEA--GKNVVFTYEEAIG-FLVFDKDGIQSAVLAA-QYLFRTELDRLYATIGYFYIETQYHFCHERKTIDAILVRDQ-TTGFGDPMITTVRASGTEP-KLKRYVE Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 NPETRAEIQQLSDLKQRLGSRIEFGTAGLRARMEAGFSRMNDLTVIQASQGLAKYVGVVIGHDHRHHSQTFANLTAAVFISLGFKVWVHTPLVPYTVKQLGAAGIMITASHNPKDDNGYKVYWENACQIIPPHDSGIAAAIDENLFVYTAMHGVGTPYPDPEFPTVAFPNPEEGKGALALAMKCANENNIILANDPDADRLAIAEKEWIIFSGNQIGTILGIAMLASTVSSKFLAKLAEANGFLFEETLTG--FKWIGNRAQELEQ--GYNAVFAFEEAIG-FTVRDKDGVSALGFFA-EWTANDYLESLYQKYGYFVTDNSYFICREPETIKKIFIRDL-TIGYSSEMITTIRTSGTEP-KIKYYSE Ustma22 DPITKNRLSILEQLQASFNGRLEFGTAGLRGIMGVGPSKMNLLTVLETSAGLAEYLGVAIAFDGRFGSKEFAYSSAQHFAFRGIPSHTPTPMCGYAVKKLLAGGIVVTASHNPKEYNGYKVYGPAGTQINTPVDGLIADEILKIAIAYSPLHGVGAPSPDGAFPTLEFPNPEE-LSTLELVHKLSEQHQLAIVNDPDADRLAVSARKLRALTGDQLGALLGIWTLSTIVSSRLLARLSGHWGGHHVETLTG--FKWLGNVARGIREG-AGSFGFGYEEALG-YMVWDKDGLSSYLLIV-SMTLWDRLEELHRLVGLSVTMQKIIKLSPTMKGTDVMVDDLKTRPAKNDVLRIVRPSGTEP-KVKIYTE Walse1 NPETRSEIEHLDELEARLGQRIEFGTAGLRAKMQAGYSSMNDLIIIPHLS------GVVVGHDHRHNSKKWAGLTTRAFLSRGFKVYVHTPLVPFGIKKLAVGGVMVTASHNPAQDNGWKVYYENAVQIIPPVDSEISQSILDNLITHTSFHGSADLSPDPDFPTLPFPNPEE-KGALTLAIETANNNGYILANDPDSDRFLAAEKKWHIYTGDEIGAILAMAMVASTVSSKMLGAMAKAEGFHFEDTLTG--FKYIGNKAIELKQ--GYSVELLYEEAIG-FGIRDKDGITAAIAFV-RLSIYAQLQNLYKKYGHFGTRNDYFKCSSNSLKDQVFVRDL-TEGHAGNMITTIRTSGTEP-KIKYYLE Zygro1 NEKTCKEIAELSELHERLNSRLQFGTAGLRARMEAGFSRMNTLVVIQATQGLAQYIVAVVGHDHRFNSMDFAKATATVLLKAGFEVHVHTPMVPFTVDRVASVGVMITASHNPKLDNGYKVYYANGCQIIPPHDSAIARSIESNLFVYTPMHGVGYQVPDPEFPTVQFPNPEE-KGALDLAIKLAENHGLVIASDPDADRFSVAFK-WQQLSGNDIGFLFALAMLNSTVSSQMINSMAALEGFHHEDTLTG--FKWIGNRALELAR--GYYVPFGFEEAIG-YMEHDKDGISAAVVFL-QASPLDILDEASAKYGVFREYNGYYLVDEPSLTNKTFFRDL-TTGYSSQMITTLRGSGTEP-KLKVYIE [Cluster2316.fasta_al_trimmed; alignment length = 87] Allma1 SARVRFCSDCNNLLYPREDRNRLLYACRCVYRHEIGETG-RLRDLIKDPTLPKA-SCPQCGSAV--YFQSRANHKDATMTLFYV--C Ashgo11 MTTFRFCRDCNNMLYPREDKQRLLFECRLVYRHELETAG-VVQDIGSDPTLPRS-DCPRCHDNV--FFQSQQRRRDTSMVLFFV--C Aspfu1 QIHFRFCRECSNLLYPKEDRNRLMFTCRCVYQNKLDTAG-VTQDVGSDPTLPRS-NCPSCGEAV--FFQSQQRSAETGMKLYYV--C Aurde31 MASLHFCSECNNLLYPKADQRVLVYACRCVYRNDLEQAG-ETQDLASDPTLAHS-NCPKCGDAV--FYQDQSKRTETRMTLFYV--C Batde5 ------------MLYPKEDRRKLLFACRCVYSHTIEQTL-VVIDLKSDPTFPRSK-CPKCSEAV--FFQSRSKGADATMKLFFA--C Botbo1 MATLSFCQECNNILSPKADPRIMMLWCRCVYKNDLEQAG-VTHDLGTDPTLPHQ-ECPSCNDSV--FYQDQSKRTETRMILFYV--C Botci1 ------------MLYPKEDPHRLQFACRCVFRNVLETAG-VTQDVGSDPTV-----CLLCG--H--LV------------------- Caeel FVGIKFCPECNNMLYPREDKRVLMYSCRCIYVNKLELTQ-IVGDIIHDPTLPKTEECPVCGKAV--FFQAQTKKAEEEMRLYYV--C Canalb1 MASFRFCAECNNMLYPKEDKQRLLYACRKVYRHELATAG-VVEDIGNDPTLPRS-DCPDCGECV--FFQSQQRRKDTSMILFFV--C Cangl MTTFRFCRDCNNMLYPREDKNRLLFECRLVYRHELETAG-VVQDIGSDPTLPRS-DCPKCHENV--FFQSQQRRKDTSMVLFFV--C Capow SGAIKFCSECNNMLYPAEDRSTLMYRCRRVYLHSNDDVSRILSDVAMDPTLPRTHDCAKCGEAV--FFQAQMRRATSGMQNFYV--C Catan2 RARARFCLECSNLMYPKEQYKQLIYACRVVYRHEVAESN-RVDFMMQDPTLPRA-DCAQCQTQAI-YYQSRSQHKDAKMILFYM--C Cioin --------------------------------------------------------------------------------------- CocheC53 PILFRFCSECSNLLFPREDKNKLLFACRCVMRHEIATAG-VTAEVAQDPTLPRV-QCTECGEAV--FFQSQQRTAETGMALYYV--C Coere1 MSSIKFCQDCSNMLYPRVDQRRLMYACRCVFRHGVEKTM-MVTDLGSDPTLPRTTECPKCSLAV--YFQSQSRHSETRMTLYYV--C Conco1 YEDTRFCKYCKNITYPKENKQELYMACRRVFYHQISMVE-SIEEEITDGTLPITDKCPKCKNAA--YFQSRSRRPDSTMALNYV--C Conpu1 MASLHFCSECNNLLYPKADPRNMVYACRCVYRNDLEQKG-VVTDLGTDPTLAHS-NCPRCHDAV--YFQDQSKRKETRMILFFV--C Copci MASLHFCAECNNLLYPKGDNQQLAYACRCVYKDDLEQVG-VTTDLGSDPTLAHS-NCPKCGDAV--FYQDQSKRKETRMILFYV--C Croqu1 MSSLRFCRDCANLLYPRADKKVLTYACRSVYRNDLESAG-VTQDLNTDPTLPRA-TCPFCEEAV--FFQDQSKRHLSTMTLFYV--C CryneH991 MPTLKFCGECNNLLYPKSDNKVLLYQCRCVYKHDLEQPG-ETKDLDTDPTLQRS-DCPACHGAV--FFQDQGRRITTNMTLFYY--C Crypa2 PVSILFCRECSNMLYPKEDKRRLMYQCRCVYRNILDTAG-VTHDVALDPTLPRS-DCPACGEAV--FFQSQQRTRDTGMKLYYV--C Debha1 MASFRFCAECNNMLYPKEDKARLLYSCRKVYRHELETAG-VVQDIGSDPTLPRS-SCPDCGDSV--FFQSQQRRKDTSMILFYV--C Dekbr2 -MSFRFCAECNNMLYPKEDKKRLLYQCRRVYRHELETAG-VVEDIGSDPTLPRT-HCPKCGDCV--FFQSQQRRRDTSMVLFYV--C Dicdi ---MYSHTHSNNMLYPKADKKTLLLACRCVYRNEIEKTQ-ISQDIASDPTLPRTKACPSCGEAA--FFQSM--TAANGMTLFYV--C Dmel FVGIRFCQECNNMLYPKEDKKILLYACRCIYVNKIELTH-IVPDVISDPTLPRTEDCPKCSEAV--FFQAQTRRAEEEMRLYYV--C Enthi AVKPHFCPDCHQIMLPRSCG--LYFVCRCVYIKNFTT---VAADVSKDPTYPKT--CPHCGDAV--YYYSAHWNYNCSLQINYQ--C Falba ---MRFCSSCNNILYPEEDPKVLILKCRVVYTNYIDQQT-EYGDVTTDPTLPRR-SCELCNTTLIFFLASRSPEAD--FSLIYV--C Fomme1 MASLHFCSECNNMLYPKADARVMVFACRCVYRNDLEQVG-VTTDLGSDPTLAHSEDCPSCGDSV--YFQDQSKRRETRMILFFV--C Fusgr1 QITFRFCSECSNMLYPKEDQHKLQFTCRCVFRNNLETAG-VTQDVGSDPTVSDLPPCTSCGDCH--MVASLNK-------------- Galma1 MASLHFCQECNNLLYPKADPRIMVYGCRCVYRNDLEQVG-VTADLGADATLAHS-NCPSCGDAV--FYQDQSKRKETRMILFFV--C Ganpr1 ------------LLYPKEDKRRLLFVCR-VFRHEVEQTM-IIKDLGTDPTLPRAD-CQKCGEAV--YFQSRARRADTSMRLYFA--C Gloin1 MATFKFCKLCSNLLYPREDKHKLFYACRCVYRNELEVTT-IIRDIACDPTLPRTE-CPECGEAV--FFEQQSRRSDTKMVLYYA--C Hisca1 QIHFRFCRECSNLLYPKEDRNTLMFTCR--------------------PCLPRS-NCPSCGEAV--FFQSQQRSAETGMKLYYV--C Klula1 MTTFRFCRDCNNMLYPREDKHKLLFECRLVYRHELETAG-VVQDIGSDPTLPRS-DCPKCHENV--FFQSQQRRKDTSMVLFYV--C Lacbi2 MASLHFCSECNNLLYPKADQRIMVYACRCVYRNDLEQVG-VTTDLGADPTLAHS-NCPRCGDAV--FYQDQSKRKETRMLLFFV--C Lenti61 QASLHFCSECNNLLYPKADPRVMVYACRCVYRNDLEQVG-VTADLASDPTLAHQ-KCPKCGDAV--FFQDQSKRKQTRMILFYV--C Malgl1 --------MCTSRL-----------AC--------EQPG-IIDELMTDPTLRRTQDCPSCGESV--MFQDQSKRTYNKMIFFYV--C Mellp23 MSSLRFCRDCANLLYPRADKKILTYACRSVYRNDLESAG-VTQDLNTDPTLPRA-TCPYCEEAV--FFQDQSKRNLSTMTLFYV--C Mnele FVGIMFCPECNNMLYPKEDKKKLMYHCQCIYVNKIELQN-IVGDVITDPTLPRT-------DEL--KKKTTSKLTERKKALL----- Monbr MGLFLRHANSNNMLAPMEKNFKLVYTCKCTYVSRANLAQ-INADVRDDPTLPHEDDCPKCSDAV--FFQAQSHRDQVGMSLFMILRC Morel2 MPSFLYCSECNNLLYPREDRRSLMFACRCVYRNEIEQTL-LVQDLSTDPTLPRTR-CSKCGEAV--FFQAQGNSAETKMTLYYI--C Mucci2 MATFKYCLECNNLLYPREDKRKLMFACRCVYRHEIEQTM-MLADLSTDPTLPRAN-CAKCGEAV--FFQSSSRRADAKMTLFYV--C Mydma FVGIKFCQECNNMLYPKEDKKILNYSCRCIYVNMIELSQ-IIGDVVTDPTLPKTTDCPKCGEAV--FFQSQSNKA-DHMRLYYV--C Neucr2 QITFRFCSECSNMLYPREAENKLLFTCRCIYRNILETAG-VTQDVASDPTLPRA-ICPACHEAV--FFQSQQRTSETGMKLFYV--C Orpsp11 -----------------------------------EETM-VITDLSADPTYPRDNNCPKCGEAV--YFQSRSRRADTSMRLYFA--C Pench1 --------------------------------------------------------------------------------------- Phybl2 MASFKYCLECNNLLYPREDKRRLMFSCRCVYSHKIEQTM-MLTDLATDPTLPRAN-CPQCNEAV--FFQSSSRRAEAKMTLFYV--C Picst3 MASFRFCAECNNMLYPKEDKQRLLYACRKVYRHELETAG-VVQDIGSDPTLPRS-DCTKCGECV--FFQSQQRRKDTSMILFYV--C Plicr1 MASLHFCSECNNLLYPKADQRIMVYACRCVYRNDLEQVG-VTTDLGSDPTLAHS-NCPRCGDAV--FYQDQSKRKETRMILFFV--C Polpo ---MNFCGECNNLLYPIADKRELLLSCKCVYRNEIERTQ-ISHDIASDPTLPRTKGCPACGEAI--FFQSMG-QKSDKMTLFFI--V Pucgr2 MSSLKFCRDCANLLYPRADKKVLTYACRLVYRNDLESAG-VTQDLHTDPTLPRS-RCPHCEEAV--FFQDQSKRNLTTMTLFYV--C Punst1 MASLHFCSECNNLLYPKADPRVMVSACRCVYRNDLEKIG-VTTDLGTDPTLAHA-QCPDCHDAV--YFQDQSKRKETRMILFYV--C Rhior3 --------------------------------------M-VLHDLGTDPTLPRAN-CPRCGEAV--FFQSSSRRAEAKMTLFYV--C Rhoto1 MADIQFCKECSNLLYPKEDKHVLLYSCRCVYKHDLETAG-VTQDLDTDPTLPRS-NCPRW--SV--FFGDQGRRAQTSMTLFYN--C Rozal11 --------------------------------------------------------------------------------------- Sacce1 MTTFRFCRDCNNMLYPREDKNRLLFECRLVYRHELETAG-VVQDIGSDPTLPRS-DCPKCHENV--FFQSQQRRKDTSMVLFFV--C Salro HVGIDFCSECNNMLHPAESATRLVFKCRCVYVNNISLTR-MNPDVIADPTLPHSRSCPQCADAV--YFQAQVNREKSNMQLFYV--C Schco3 TPALHFCTECNNLLYPKADRNRLYYYCRIVYRNDLEQMG-EVSNLETDPTLAHA-ECPACHDAV--IFQDQSKRHQTRMILFYV--C Schpo1 MSNFQYCIECNNMLYPREDKRVLRLACRKVYRHELENTT-VSHDASTDPTLPRS-DCPRCHEAV--FYQTHSRRGDTMMTLIYV--C Sorma QITFRFCSECSNMLYPREAENKLLFTCRCIYRNILETAG-VTQDVGSDPTLPRH-ACQCCGEKCSNHFAAPHSDSESSAG------- Sphar --------------------------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------------------------- Sporo1 MASIRFCGECNNLLYPKEDKKVLLYSCRCVYRHDLENAG-VTQDLDTDPTLPRS-NCPKCGESV--FFGDQAKRTTTTMILFYN--C Stehi1 MASLHFCGECNNLLYPKADQRTMVYACRCVYRNDLEQVG-VTNDLGVDPSLAHS-NCPKCGDAV--FFQDQSKRKETRMILFFV--C Tapde11 --------------------------------------------------------------------------------------- Thetr ---MEFCVECNNLLHPKCSQFVLNLECMKVFTRKVDTASQITDEVISDPTLPRSFQCASCGEAV--FFQSHIKTGDT-MTLFFV--C Treme1 MAALRFCGDCNNLLYPRSDNHVLLYMCRCVYKNDLEQAG-EIRDLDNDPTLQRS-NCPHCQGAV--FYQDQALRVTTNMTLFYV--C Trire2 QITFRFCSECSNMLYPKEDERKLQFTCRCVFRNVLETAG-VTQDVASDPTLPRS-NCPKCAEAV--FFQSQERSADTGMKLFYV--C Umbra1 MASFKYCSECNNMLYPREDKRKLLFACRCVYRHEIEQTM-VLTDLSADPTLPRTT-CPRCGEAV--FFQSAARRADTKMTLFYV--C Ustma22 MSSLHFCAECNNLLYPEVDRHVLLYACRLVYRNDLEQPG-IVDNLMKDPTLRRTHDCPNCGEAV--LFQDQSKRIMNRMILFYV--C Walse1 -MSLKFCQNCNNLLYPREDRRTLLFACRRVYRNDLEEAG-VTQDLGKDPTLPRT-NCPKCLQSV--FFQDQSKRTETRMTLFYV--C Zygro1 MTTFRFCRDCNNMLYPREDNQRLLFECRLVYRHELETAG-VVQDIGSDPTLPRS-DCPKCHENV--FFQSQQRRKDTSMVLFFV--C [Cluster2321.fasta_al_trimmed; alignment length = 101] Allma1 KAGGLVFQRLSTNDYLVLAGTFHGIHAITSRISPSTGIEVLETDTFTATCHQTPTGIKIVLFTDEALMRRVYDLYADYVMKNPFYTPEMPVR-CELFDVHL Ashgo11 KSGGLVYQRMSSNEYLILAGTLHGVIAIASQLTPRSGLKSVVMDECSLFVYQSLTGVKFILLSTENLLRKIYCIYSDYVMKNPFYSADMLIR-SEPFDKRL Aspfu1 KAGGLIYQRLSTNDYLVLAGTFHGVHAITRSITPVTGLESLETDKFRLTCFQTLTGTKFLLFTDDAVMKKIYELYSDYVMKNPFYQLEMPVR-CEAFDRHL Aurde31 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRISPSSGVQVIEGEVFKITIFLTLTGTKFVLLTSDAMLHKVYEVYADTVAKSPFHNPEMPIR-VEGFDSRI Batde5 KAGGLIYNKLTINEYLVLAGTVHGVHAITSQLSPSSGFELLESEALKMYCHQTQTGIKIVIITDEPVCRRIYELYADYAMKNPFHTPEMPIR-ADLFDLSM Botbo1 KAGGLVYNRLTSNEYLVLAGTLHGIHAITSRLSPSSGAQVIEGESFKMTIFLTATGTKFVLLTSDVILHKTYEIYSDTVMKNPFHTPEMPIR-TEGFDSRI Botci1 ----MCWSAPGKAAYLTVLGRGYRVHAISTRLNPPSGIEVLETTLFRLQCFQTLTGTKFLLFTEDSILRKIYELYADYVMKNPFYQLEMPVR-CERFERGV Caeel RAGSLIYSWVSTNEKIILSSMFHSLFTIAVQLSPSSGVEVLETTQFKLFCLQSRTGVKFVVITSDSLLSKMYELYTDFALKNPFYSIDMPIR-AQKFDEAI Canalb1 KAGGLIYQNLSANDYLVLAGTLHGVHAIGSKLSSRTGLQKIETDMFNLYIFQTVSGLKFIMITADELFRHLYILYSDYVMKDPFYSLDMPIK-SSLFDGRV Cangl KSGGLIYHRMNSNDYLILASTLHGVFAIATQLTPTSGIRHMSTDQFTMFIYQTMTGLKFVAIKNDNLLRKVYCLYSDYVMKDPFYSLEMPIK-STTFDEKL Capow KAGGLIYGQLRANDRLTLASMFHSLYAITSNLSPSSGIEVIETDTFKIQCKQTLTGTKFFVMSDDALLRRLYELYSDYVLKNPFYTPEMPIR-CELFDINL Catan2 KAGGLIFQRVSTNDYLVLAGTFHSVHAIAARISPSSGITSLETDTFTLTCHQTHTGTKFLIFTDDQLVRKVYDLYADYVMKNPFFTPEMPVR-CEQFDVHL Cioin KAGGLVFQYLSSNQKIMMASMFHSLYAISVQLSPSSGIQKLETDTFTLHCHQTVTGVKFIVISDDSLLARLYTIYSDYALKNPFYSLEMPIR-TELFDSQV CocheC53 KSGGLVYNRLTSNDYLMLAGSFHGMHAITAQLSPATGIEVLESSHFRIQCFQTQTGVKFLLFTEDTMIKKIYELYADYVMKNPFYTVEMPIR-CDKFDRGL Coere1 RSGGLIYNKFSSNEALIFAGTFHGIHALASRISPDLGIQTIDTKGFRLHCFQTPTGIKFIAVADVDVLSKAYRLYCDYALKNPFYNLEMPIR-SDMFDTML Conco1 KSGGLIYQSLSSNEYLVLAGTFHGVHALTSQISPSKGITSLETNQFKLTCFQTLTGIKFLLVSDNLITKRVYELYGDYVLKNPFYTPEMPIR-CELFDINL Conpu1 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRISPSSGAQVIEGETFKMTIMLTATGTKFVLLTSDVILQKVYEAYSDAVMKNPFHTPEMPIR-SEGFETRV Copci KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRLSPSSGAQVIEGETFKMTIFLTATGTKFVLLTSEILLQRIYEAYADSVMKNPFHTPEMPIR-SDGFESRV Croqu1 KAGGLIYQKLSSNDYLILAGTFHGIHAISSKLSPGSGIQFMEAETFKISCLQTLTGIKLLIFTSNKLLKKVYEAYGNL-LKDPFYTAENPIR-NESFDARC CryneH991 KAGGLVFSRLPVNTILTLAGILHGIHAITARLTPAGGLESFEAEGWGGKVFLTPTDVKAKTREDSGRM----ERDEDSVMGK------------------- Crypa2 KAGGLIYNRLSSNDYLVIAGTFHGVHAITTRLNPSSGLEVMETENFRLQCFNTMTGTKFLVFTDDVTTRKIYELYSDYVMKNPFYQLEMPIR-CEMFDRKL Debha1 KAGGLIYQNLGANDYLVLAGTLHGVHAIASKLTHKSGLQSIETDFFNLYIFQTLTGLKFIIVTSKDIYNQLYVLYSDYVMKDPFYSLDMPIK-SSLFEMKV Dekbr2 KSGSLLYQKQNSNDYLVIASTLHGVHAIASKLTPRFGLQCITTAKFKIFIHQTTTGLKLILFTSTQLQGQLYKSYADYVLKNPFYRLDMPIR-FRLFDDKV Dicdi KAGTLIYQNLSHNSYIRLGSTFHSLHAIASNLSPSSGIEVIETEAFKLQCFQTHTGIKFYVIADEELLHGVYELYTDYVLKNPFYEIEMQIR-CDLFDYKL Dmel KSGGLIFNLMTTNEKIFLASMFYPLFAIASQLSPSSGIEILEADTFTLHCFQTLTGIKFIIISEDLLLRKVYELYSDYVLKNPFYSLEMPIR-CELFDNKL Enthi KTGTLQWMRRTENDPLYLASSFHGFSVVASQINPSDGIQKIQTSNFSLQCLHTQTGVEFLVIASGEFLSQLYILYTDYVLKNPFIISEMIIK-SKKFETKV Falba KAGGLVYQHPNSNDFLMLAGTFHSIHALVAQFSPSSGLRVLESSHFTLFCFQAPTGTKFLLVTITAAWREIYLAYGAFVARDPFHVPEMPIR-CSRFDAAV Fomme1 KAGGLVYQRLSANEYLVLAGTLHGVHAITSRLSPSSGAQVIEAETFKMTILLSATGTKFVLLTSESLLQKVYEAYADMGMKNPFHTPEMPIR-SDKFDTRI Fusgr1 ---------TSTSS----------VHAITSRLNPPSGLEVLETENFRMQCFTTMTGTKFLLFTDDVTIRKIYDLYSDYVMKNPFYSLEMPIR-CDIFDRKL Galma1 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRLSPSSGVQVIEAETFKMNVLLTVTGTKFVLLTSDTVLQKVYDIYADAVMKNPFHTPEMPIR-SEGFDTRI Ganpr1 KAGGLVFNKLSNNEYLVLAGTLHGIHAITARISPSSGLELLETDTFKLHCFQTLTGTKFILITDDTIMRRIYEIYSDFVMKNPFTNPDMPIR-AELFEANL Gloin1 KAGGLIYQRLTSNEYLVLAGTFHGVHAITSKISPSSGLEVLEADTFKLHCFQTLTGTKFLIIAEDLLLRRTYDIYSDYVMKNPFYTPEMPIK-SELFDINL Hisca1 SAGTAIPSH---------------THAHSSSSS-ITGIEVLETDKFRLTCFQTVTGTKFLLFTDDVVMRKIYELYADYVMKNPFYQLEMPVR-CEAFDRHV Klula1 KSGGLVYNHMNSNDYLILAGTLHSVFAIASQLTPKSGLRHMITDEFSMFLFQSLTGIKFVLISTENILRKIYCIYSDYVMKDPFYSLDMPIR-SELFDSNL Lacbi2 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRLSPSSGAQVIEGETFKMTISLTVTGTKFVLLTSDIILQKVYDIYADAVMKNPFHTPEMPIR-SEGFDARI Lenti61 KAGGLVYERLTSNEYLVLAGTLHGIHAITSRLSPSSGAHVISGETFKMNILLTATGTKFVLLTSDSVLQKVYEIYADAVMKNPFHTPEMPIR-SEGFDTRI Malgl1 KAGGLVFQSLTSNDYLILAGTLHGIHAITSRIIPSQGFEVLEADGLIIYVKMTETGTKLVLLTYAGILQRANELYVDHVMKNPFYIAEMPIR-IESFDREI Mellp23 KAGGLIYQKLSSNDYLILAGTFHGIHAITSKLSPGSGLQFLEAETFKVSCLQTLTGTKFVIFTSNKLLKKVYEAYGEL-LKDPFYVVENPIR-NEAFDLKT Mnele KAGGLIYDEVGANEKLMLASMFHSLYAIASKISPSSGIQQLVTDEFSLHCFQTITGVKFFVIVDEPLLHRIYELYTDFVLKNPFYLIDMPIR-CELFDQNL Monbr KAGSLLYSK-ETNEKLRMASLLHGLSAFALQLSPQHGITDVVTTHYRLCRFESQSGMQFVVIVDGHFLHRLHQLYADYILKNPFYTLDNPFHGSDLFEREL Morel2 KAGGLVYNKLTSNEYLVLAGTFHGVHAITSKISPSSGIEMLETDTFRIHCFQTLTGTKFLLVADDMTMKKIYEIYSDYTVKNPFQNPEMPIR-SEQFDVHL Mucci2 KAGGLVYQKLSSNEYLVLAGTFHGVHAITSKISPSSGIEMLEAENFKLYCNQTLTGTKFLLITADAYMKKIYDTYSDFVMKNPFHTPEMPIR-SDQFDQSL Mydma KAGGLVYQRLSTNERIMLASMFHSLFAISCKLSPSSGIEIMETNSFKLHCFQSITGVKFLVLTNDVFLKKMYEIYSDFALKNPFYSLEMPIR-CDLFDNAL Neucr2 KAGGLIYNRISTNDYLVLAGTFHGVHAITARLNPPSGLEVLESENFRLQCFNTLTGVKFLLFTDDVIIRRIYDLYSDYVMKNPFYQLEMPIR-CDMFDRKL Orpsp11 ----------------------------------------------------------------------------------------------------- Pench1 KAGGLIYQRLSTNDYLVLAGTFHGVHAITRSITPVSGLDYLETDKFRMTCFQTLTGTKFLLFTDDTIIQKIYELYADYVMKNPFYQIEMPVR-CEAFDRHL Phybl2 KAGGLVYQKLSSNEYLVLAGTFHGVHAITSKISPSTGIEMLEADTFRLFCFQTLTGSKFLLFTDEPYMKKIYDLYSDFVMKNPFHTPEMPIR-CDRFDQSL Picst3 KAGGLIYQNLTANDYLVLAGTLHGVHAIASKL--KSGLQSIETDLFNLYVFQTLTGIKFIIITSNEVFKQLYIVYSDYVMKDPFYSLDMPIK-SFLFDTKV Plicr1 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRLSPSSGAQVIEGESFKMTILLTATGTKFVLLTSETVLQKVYETYADAVMKNPFHTPEMPIR-TEGFDARI Polpo ----------------------------------------------------------------------------------------------------- Pucgr2 KAGGLIYQKLTSNDYLVLAGTFHGIHAITSKLSPGGGVETVEAETFKMSCFQTLTGTKFVLFTSSRLLSRIYGVYADL-LKDPFYSVENPIR-NETFDKRC Punst1 KAGGLVYQRLTSNEYLVLAGTLHGIHAITARLSPSSGAQVIEGETFKMTIHLTATGTKFVLLTSETVLQKVYEAYADAVMKNPFHTPEMPIR-TEGFDSRI Rhior3 KAGGLVYQKLSSNEYLVLAGTFHGVHAITSKISPSSGIEMLEAENFKLYCNQTLT-----VILS------------------------------------- Rhoto1 KAGGLIYSRLNSNDYLILASTFHSIHAIASRISPSSGVETIEAETFKMTCLQTPTGIKFVLLTTETVLRRIYETYADH-LKDPFYTVEMPIR-SETFDSKM Rozal11 ----------------------------------------------------------------------------------------------------- Sacce1 KSGGLIYQRLNSNEYLILASTLHGVFAIASQLTPKSGLRQLCTDQFTMFIYQTLTGLKFVAISSDNFLRKVYCLYSDYVMKDPSYSMEMPIR-SNLFDEKV Salro KAGSLLFSGMDANSRLRLAGLLHGLTTFAGKLSPQSGIEEIEGDGFRLERFQPLSGMQFVVLCDKPFLRKCHRLYADFVLKNPFYSIDMPIR-CELFDTHL Schco3 KAGGLVYQRLTSNEYLVLAGTLHGIHAITSRLSPSSGAQVIEGESFKMNIFLTQTGTKFVLLTSDSILQKAYEAYGDTVMKNPFHTPEMPIR-SDGFDQRI Schpo1 RAGSLIFQRLTPNEYLVLAGTIHGVHAISTQISPSSGIQLLEAGTFNMHILQTHTGMKFVLFTERLQLQKFYELYSDYVLKNPFYTLEMPIK-CQLFDEQL Sorma MPGANTYTQLSTNDYLVLAGTFHGVHAITARLNPPSGLEVLESENFRLQCFNTLTGVKFLLFTDDVIIRRIYELYSDYVMKNPFYQLEMPIR-CDMFDRKL Sphar -------------------------------------MEILETSTFKLQCFQTLTGTKFLVVTDDAVLRGLYVLYSDFALKNPFYSMENPIR-CELFDQGL Spipu1 KAGGLIYNRLTSNEYLVMAGTFHGVHAITSRISPSSGMEVLETDTFKIFCFQTLTGVKFLLITDDVPSRRVYELYADFVMKNPFYNPEMPIR-IDLFDANV Sporo1 KAGGLIYSRLNSNDYLILASTFHSIHAIAARISPSSGVEMIEAETFKMTCFQTPTGIKFVLLTTGTVLKRVYETYADQ-LKDPFYTVEMPIR-SETFDLKM Stehi1 KAGGLVYQRLTSNEYLVLAGTLHGIHAITARLSPSSGATVIEAETFKMHILLTATGTKFVLLTSDSILQKVYEAYGDAVMKNPFHTPEMPIR-TEGFDARV Tapde11 ----------------------------------------------------------------------------------------------------- Thetr KAGGLIYQKLMVNEHLRLGGFFHGIHAIAAQVAPSSGVEEIEASTVKLRCFQALTGTKFFVTASDVFLSQVYEYYADFVLKNPFYELEQPIQGCDKFVAHL Treme1 KAGGLVFSRQTLNATLILAGTLHGIHAITSRLNPKGGLESFEGENWGGKIWMSLTGIKFVVLHSDELMRKIYEIYSDAVMKNPFQTLEMPIN-SSLFESRL Trire2 KAGGLIYNKISTNDYLVLAGTFHGVHAITARLNPSSGLEVLETENFRMQCFNTLTGTKFLLFTEDVTIKRIYDLYADYVMKNPFYSLEMPIR-CDIFDRKL Umbra1 KAGGLVYQRLSSNDYLVLAGTFHGVHAITSKISPSSGIEVLEAETFKLICTQTLTGTKFLLVTDEVLQKKVYDLYSNFVMKNPFHTPEMPIR-SDQFDAGL Ustma22 KAGGLIYQSLSSNEYLVLAGTLHGIHAITAKLNPCSGIESLESDHFTIRVMVTSTGTKFVLVTSSGVLHKCYETYADHVMKNPFYTPEMPVR-VETFDKAI Walse1 KAGGLVYLRLNTNEQLVLAGTLHGVHAICSRISPSSGMQLLESDSFDLTVFLTRTGTKFVLITTQALLNRVYEIYADTVMKNPFHIPEMPIR-NEMFDTAL Zygro1 KSGGLIYHRLNSNDYLILASILHGSFAIATQLTPRSGVRQLCTDQFTMYIYQTMTGLKFVVACSDNFLRKIYCLYSDYVMKDPFYSLEMPIK-STLFDKKV [Cluster2324.fasta_al_trimmed; alignment length = 217] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 PFQGRYVAALLLGTKRYLTMNGIGYVWTVVTVSFFDVGREYHFEDYDLCSLTDEGTFFGLLYRVSEIITGIASTLVVATSLGYIRTFNEHGLPPIVALAAHKIFAVYSLFESLPLTIKSLFFSTGDPCIF-GSDNVLLVLSRWVPIVDSNVWPLGLNYDMLNYILIPLPSEMEIRLPLRLFASACSDHNTEKALSLVKELKA--LNAAQKIALVSSI Aspfu1 P-NGALLATLSFTTRRYLCLNLTGCVWTVVTVEFYDRERDFHFTDYDRACLNENGTLFSIFYRPGELIRALALSIVAVTTKDYVRVYTLFGTPPAVTCAADYVMTIYSIENVVALPLRSVFFSDGDPCIY-DSEGVLLILARWVPLLDTKYWPVAVAQEKFHCIILPLLSEFDFRIPIQMLAVECREERGMKALELVRMMNGKMIEAAAKIALEDKI Aurde31 P-NGFYLAVLAWVDKSYLAHNTIGVIEVTVSVEFYDKSRGYNFQDYSLAALGERGAIFAITYKPGEKVVAVAAGAIVATSAGYVRFFSGAGLQTVVSMVAEWVFIVYSLVAPLPLPLKWIGITEGAPAMY-DSAGILSILGRWVPILDTMYWPVGLSNTIFMCLILPLVQELEVHVPLQLIQSACKQTKLQRALDLASLLMS--FDTAIKVALQERL Batde5 P-NGMYLLTLLTIDKRYLAFNLIGVVSSLVNVEFHDKSRPFHFTDYTMSALNESGAVFAIFFRPKESALAVALTIVVATDLGYLRYFSYGGSQPILTMAGKYLFIAFILMDNLPISLEWVGFSDMIPLTY-DTKGILRGMASWVPLLDTDYWALGVVGSQFMCIICPIINELPLQVPFKLIHGACTAERSQRALDLCSMLKS--LEGATKLALASRI Botbo1 Q-NGHYLASLAWTDKRFLAFNMIGVVEVTINVEFHDQSRGYHFQDINMASLGERGALYAINYKPNEQVIAIASGVVVATSKGYVRFFTGGGMQEVVAMVAEWVFVVFTLIARLPLLLKWIGFTEGVPAMY-DSNYIVSILGRWVPVLDTNYWAVGLSEQSFSCIILPLIQELDVQMPLGLIQAACKADQLQRALDITNMLAS--FDTAAKLAVQEKI Botci1 P-NGAMLASLSFTNRKYLCLNLIGFIWTIISAEFYDRERDFRFTDYDKACLNENGSLYSILYRPGEEVSAIALSVTVTTTKNYVRIYTLFGIPPMVTCASDYVLTLYTIQNVVALPVKSVFFSDGDPCIY-DSTGTLLTLASWVPLLDTKYFPVAVSDNKFHCIILPLLSEFDFQIPIRMMMAECIEERGMRALEMVQLMTGKFIEAAGKVALGEKI Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 A-QGN-LAILFVGSRRYLTMNNIGYTWVVITVSFFDRSTEYHFTDFDLASMNQRGVLLGIYYRSSEYITSICITIIVGTNLGYLRFFNQFGVCPVVTLIAAKLFVIYSILDPMPLKIKGIFFNENDPCIVGGEDDTLLILAKWIPILNCHCWPLGFIGDKLNCLILPLPIELEVELPIKLFGESCKESKLGKAFSIARLIKA--LLAASRIALASKI Cangl TKNGNYMAALILGTRRYLTMNEIGYVSTVVTVSFFDVGREYHFEDYDVCFLNENGTLLAINYRPGERITTIAATVYIGTSFGYFRIFNSFGVPPIVALTAYKVFTVYSLFEPLPITIKSLFFSSGDPCIF-GIDDVLLVLSRWIPVLDSNVWPLSLNYDTLNCILVPLPSEMEVQIPVRLFAIACSDQNPERALSIAQELKA--LTAAVKVSLVQKI Capow S-NPRILASIAMIDRRYMAYNEIGYITSRIDVHFHDAARSIKLTDFTLAFLSEHGVVFAICYRMNESARAVAAEVAVATDRNQLRLFSATGVPPVVTMTADCLFVVATPSSSTTSTLVWVGFTAGVPATC-DSLGIVRVLSIWMVLTDLALWPIAISDAQVRVLLCGMADAVQSLVPIPMIAAAISSSRHMRALELCCRLDS--IDRMIQYALVDRM Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin Q-CGRFLAAVAFSDHRFMVWNAVGVIRSYIDVEFHDTQHALHLPNYTMADLSVQAVVLALKCVHGEEIQAVTTGIAVCTDALQVRFFSLGGIQNVVAMAADQLLVVFMLLEPLPISLEWVGFTAGTPATV-DTLGVVRMIQTWTTVVKLKCWVVGLHENQIRYIQCPTMAVAHYKIPLRLFALCCKSDAEYQAFDVCSMMAS--MSLAIKYSLAQRL CocheC53 P-NGALLATLSYTNRRLLCCSLTGYVETVVTVKFYDEHRNFHFTDYDKACLNEKGTLFAIYYRPGESVTAIALSVCVTTSTNYVRIYSLFGLPPAVTCAADYILTIYTIENILALPLTSVFFSAGDPYIY-DSEGVLLTLARWVPMLDTKYWPVGVASSKFHCMIIPHLSEFGFEIPLQLLGLECLEDHGMKALEIVSLMNGKMLDLAGKVALGDKI Coere1 A-NGKYVASLAFTDRRYLAFNLVGSVTVIVEIEFFDKSRDLHFSDFSMAALSDTGCLFALSYRGKEHPRCIAASAAAITSQGMLRLFTCGGVQRAVTCAADLLLVVYLLMSACPVSVVWAGFSEGHPATC-DSKGMLRVLASWMPVLDTRFWPVALSARQFIVVTCPILDELDVEMPLRLIQLACKADKSQRAVDLALMIRS--FDAALKIALAERL Conco1 P-NGKYLATLGFTDQSILHFNTQGYIRLSISVNYFDTTQNVNLTNYNIGYLNEYGFLLVIYFQTKVNIVGCCLTPLIITDDCRLHWFSKSGQENFVS-CAEKIFLLFVVLEAIPVTVEWIGLSDGLPMMF-TSDGSFLVYGFWYPVLDIPHYPIGGSLGQVYLVSVPSIIQETWSIPLKYIYHTAKNQPDVKTLDLCKNLED--IQNVIKLVLVQKL Conpu1 A-NGAFLASLAWIDRRYLAYNMIGVIEVTVNVEFHDRSKSYHFTDHDLASSGERGAVFAVIYKPGQRVLGVAAGVVVATSAGDLTFISGSGVEEFVTMAAEYVIVVATVISPLPIPLKWIGITDGIPAIY-DSAGYLHIMATWARLLDTNYWPVGCSNETFHCLILPLIQELPIRMPFRLIQAACKTDKQPRALELAKRLQS--LAAAHKVALREKF Copci P-NGEYLASIAWTDKRYLAFNMLGVIEATINVSFFNTTPSFHFTDNDMGYLGECGAVFAVLFKPGTSVLGIAAGVVVATSENDLTFLSGTGREDLVTMVAEWVFVVYTVINVLPVPLKWVGLTEGLPAMY-DSTGYLHILAAWVRIMDTNYWPVGVSDENFMCIILPLMQELPIQLPFILIQHACKDGNTARALELVKLLPS--FDAAIAIALKEKM Croqu1 P-NGGYLATLVIGDRRYMAFNDVGFVQVLVTVEYHDRGNPYHFTDFNLCSMSELGVAFAIRYDPGENAICLACGVVVGTSKGYIRFFTGSGIQHIISLACEWLFVVYSMMDIIPLALTWIGFTTRIPACF-TSSGVLSFLGRWVPVLDTDYWPIGASDTQLSCMILPVVQEVDLSIPLKLIQTCCKTPELQRALDYANLLSS--LEAASKIPLDDRI CryneH991 P-NGKYLAVLGFTSKRYLAFNMIGVIDVTVNVEFHDKSRGYHFQDFTLASLGEQGIVYAVYYRPKENVVCVTAGVVVATSKGWVRFLSASGIQEVVSMAADRVLIAYTLLDKIPLPLTWLGFTSGAPAMF-DTSGLLSILARWVPLLDTAYWPVGVSATHLSCVLLPLIQEVELHMPMQLVQGACKADNLQRALDVARLMAT--IEAAAKVALQERI Crypa2 P-NGAMLATLSFTTRKYLCLNLIGFVWTVVTVEFYDHERDFHFTDYDKACLNENGTLFAIFYRPGEAVLAMSLGITVTTSADYVRVYTLFGLPPMVSCASDYVLTVYSIENLVALPIKSVFFSDGDPCIY-DSTGTLLTLASWVPLLDTKYYPVAVADNKFHCIILPLLSEFEFSIPLQLLAGECREERGMRALEMVELMTGRMIEAAGKVALGEKI Debha1 P-NNKHLAVLCIGTRRYLAMNSIGYIWSVITISFFDRSKDYHFIDYDLCSMNEKGVLLAVLYRFDEFITSVSLTIIIGTNLGYVRFFNLHGLCPVVTLMASIIFMIYSIIDLLPLKIKGVFFNENDPCLVPGIDDTVLILAKWIPILNCKCWPLGLYKDQLNCLILPLPIELDIKLPVKLFASACQESRLNKALSIAKLIKA--LMAASKISLASKI Dekbr2 P-DGKLLASVVVGMRRYMTMNPVGYAWSVVTVTFFDRSKEYHFRDSDVASMDADGISSAILYKKGEFITAVSSGAFVCTSRGYVRRYSSFGRSPVLACISKYLFTVYSSGFSLPVCIRGLFFSSGDPCVV-GQDNVVLVLACWMPVLDAKAWPLGSFGDKF-CFVAALPSEMPVRVPVRQVGQSCNRGDILDAFYLVTKLRA--LAAAAKMALVDKI Dicdi S-GGEYLASISFFDRYYLAYNMLGKIIKRIEIDFHDTSKKVVFPDLRIASLNSCGAIFALTFKSKDGISGVAVSIISCSENGIVRIFSLGGIQDLVTMN-DQLAIVVWWINTLPLSLSWIGFSDGLLTSM-DTGGMIRQLLQWIPITDLTYWVIGLGKKDIYSIFCQTHNYVKIELPLRLFDFYAQQGHYKKCMDLCGLLKS--LSIVFALSLSKKI Dmel P-NGERLAAVAFCDHRYMAWNDVGIVTAHIDVEFHDASHALHISNHNLASVSSGALALALVVIACESAEAVVATVAVATSSSFLRIFTVMGTQPMVAIAGHSLMVVAMLVNPVPLTLTWFGYSDGSPSIA-DNMGLLQLYNAWFPICDTMFFVVAVSEKIVQAVLCPMLQELRMQIPLKLFALACSSECETRARELIESIDL--LQLAVKYALSDRL Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba P-DGRFLAALLVASRRILAWNHVGMVLVHPQQHFYETRRRVQIQTYTMAAINEHGVVLALQFSSGEHIEAVALGVAAITSLGFIRLYTTGRLPPVAAAAGDRLVVTVTPGSALPLTLRWVGLTPKRMATF-DSQGILRILAIWTPVLDMVVWPVAVEDGQLVFLPLPLPQSSKFACPIRLLSDAIRQEHDFRAIELARLMSS--LDFCIAAALLNTL Fomme1 S-NGVYLASLAWTDRRYISFNNIGVAEVVINVEFHDQTKNYHFTDFDMASIGERGVVYAVHYKPGERAIAIAAGVVIATDRGVVRFFSGGGAQDIIAMVADYVFVVYTLRTRLPVNLKWLGITDGAPVIY-DSVERIMMLGSWVVLLDATYWPIGVTGSTLMTIILPLAQEIEMQMPYQLIQLACKHDRLQRALDAAKLLAS--IDMAIKVALREKF Fusgr1 P-NGAMLASISFTTRKYLCLNLIGFVWTVVTVEFYDHERDFHFTDYDKACLTEHGTLFSIFYRPGEVVTAMSLSITVTTSANYVRVFTLFGMPPMVTCASDYVITMYTIENTVALPLKSVFFSDGDPCIY-DSTGTLLTLASWVPLLDTKYFPIAVADNKFHCIILPLLSEFDFSIPIQLLAVECREERGMRALEMVQLMTGRMMEAASKVALGDKI Galma1 P-NGVYLASLAWTDKRYLAYNMVGVIEVTVNVEFFDRSKGYHFTDHDLGYLGERGAVFAVLFKPGIKCLGIAAGIVVATTENDLTFLSGTGREDFVTMVAEWVFVIYSIINVLPVPLKWIGVTDGAPAMF-DTTGCVHILASWARVMDTNYWPVGITESNFMCLILPLIQELPMRIPFQLIQGACKAGNAPRAIELTRLLAT--LDAAMKIALKEKM Ganpr1 S-SGTHLASVIFGDPRYLAFNMTGFIYTVVHVEFHDRSRPFSFTDFTLGTLGDRGALFAVVYRPNENVVAICLTAVVGTDQRYLRFFSTSGVQPLVSMTSDHFMVVYCLYNSLPISLTWIGFSENIPVTY-DSEGVLRGLYAWAPLCDTRYWPIGVTDSKLMFVITRLISELDLKAPFQLIQNACKAEKAQRALDLSTHLQS--LDGAVKLALAERI Gloin1 --------------RRYLAVNWLGCIHSVVNVEYNNKTRGYNFRDYTMACLGTHGVLFALYYKPDEEIIAIALSIAIATSNNYLRFFSLNGFQSIVCMAANLLLVAYVLYDFLPISLKWLGFSEGLPTMF-DSKGVLYILARWVPVLDTAYWPVAVMESKLMCFILPAYDEVNWQIPLELIMMAVSEEKYERALDLAKLLRF--LESALKIALAEKI Hisca1 P-NGALLASLSFTTRRYLCLNLVGFVWAVVTVEFYDRERDFHFTDYDKACLNEKGALFSIFYRPGESITAIALSIVVTTSADYVRIYTLFGTPQSVTCAADYVLTVYSIENHVALPLRSVFFSDGDPYIY-DSSGVLLVLARWVPLLDTKYWPVAVAQDAFHCIILPLLSEFEFKIPIQLLAIECREERGMKALELVSMMSGKMLDAASKVALDEKI Klula1 QIHSNTIAALVAGTKRYLTINQLGHVWTTITVSFFDVSREYHFDDYDLCSLTDEGILLGIQYKPKERVTSIACTVIVGTSLGYLRTYNDFGLPPIVALSAYKVFTIYSMFQPLPITIKSLFFSSGDPCMF-GHDNVLLILARWVPIVDTNVWPLGLNFDTFSYLLLTVPTEMEVRIPVRLLAYVCSEQDVNKAVSIVNELKA--LSAARKIALVRKI Lacbi2 P-NGVYLITIAWTDKRYLAYNMLGVIEVTVTVELFDRSKGYHFTDYDLGYIGERGTVFAVLFRPNIRVLGVAVGVVVATSESDLTFLSGTGREDFVTMVAEWVFVVYTIVNILPVPLKWIGITDGAPAMY-DSTGWVHVLASWARVMDTNYWPIGITGSNFMCLILPLIQELPVRMPFMLIQAACKADNIPRAIELTKLLTS--FDAAMKIAFKEKV Lenti61 R-NGAYLTALVWTDKRYLAYNMIGVIEVTVNVEFHDRSKSYHFTDYDLASLGERGALYSVVYKPGTRVLGVAAGVVVATSDGELLFLTGSGIEDYVSMVAEWVFIVGRLIKTLPIPLKWIGITEGAPAIY-DSAGILNTMATWMRVLDTNYWPVGVVGDNFMCLILPLIQELPIHLPFQLIQHACKTDRLARALDLTRMLPS--FNAAIKIALKEKM Malgl1 P-NGRYLAAIAWTDRRYLAVSNFGTLTSIVVFESYDTSRNFRFTDYTMASMASQGILFAIFYRPGETATAVALGSVVSTSRGMLRFFGPSGMQPVVALAAYSVMVVYMVIETLPVGLTWLGFDEGTPAVF-DSAGMLYTLGRWVPSLDCE-WPIGVTGTHLLGLLIPLVQELELTISMQLVHLAGKADRYARALDATRSLST--LDAALKIALADRM Mellp23 P-NGIYLATLVFGERRYMAFNSIGLVHALVTVDFHDQGPRYHFTDFSLCSMSELGVAFAIRYDPGESVTCLACGVIVGTDKGYVRFFKGSGIQQIISLACEWVFVVYTMMDLMPLSLTWIGFTASIPACF-TSAGVLSFLGRWVPVLDTNYWPIGVSESQISCIILPIVQEIDLQMPLKLMQSSCNAPQLQRALDYANLLNS--LEAASKMSLEDRI Mnele E-HENLIAAAIIND-------------------------------LQMAKLPER-----VKEEP-----------------------------DPVTLASDLISVAFSLYDPLPLTLSWTGFTEALPLVY-DSEGVMRGLLMWVPLSDLKYWVVSASDDAIKCVLC--------TVPLKLMALAIKNNKDFKAFELAKMMQS--LEMASRYALAQKI Monbr N-DDVYLASLAYADKRFLVWNNVGIITSRVDVEFHDTNRPVRLVDFTMGTLSEHCLVLALFCRNGEEIEVVATGVAAATSKRYVRIYSSYGVAPVVSMAADKLLIATMLVNSLPLSLSWIGFGDGLPATI-DSEEVMRVLGLWTPVAEFKYWPVGFTRDELLCVVCPAISTVPLQLPLAAISRSVQSKRAARALDLTTFLAS--VELAVKLALAERM Morel2 P-NGRFLLAITITDRRYLAFNLLGLITSVVVVEFHDKVRGFRFSDFSMAYLGINGAIFAVYYKTGEDVIGVALTAIVATSRGFVRTFSQSGVQSIVAVAGDLAIIVYLMYNPLPVSVTWLGFSEGVPAFY-DDTGVVHILGQWVPILDTNYWPVGLSDEAFTCIRCPFVTELPFKMPTKMIGFACKSGFAQKAMDLTAMLSS--VDRAVKIALTERM Mucci2 P-NGYYIASIFLTDRRYMAYNLVGAISTIINVEFHDQSRNFHFTDFTMGAISSAGTVYALYFRPGEDVVSIAINVIATTSLGYVRIFSISGVQNVVSVTADLALLVFMLLNKVQLTLNWIGFSENQAVTF-DSAGILRLLSRWVPAFDSKYWPVGVLRDRLMCVVLPPVKDIPLQLPLKLINIACKTEKVSKALDMTYILDS--IDKAIKIALAEKM Mydma T-CGKYLASILFANHRFMVWNSIGIIRCHIDVEFHNASYPLHIANNTMGTLSNTVIVLAVTCHHNESIQVIAANVILATTQQYLRFFTISGIQSVVTMAVKQLLIVVLCMHPLNLRLVWLGFSTGSPVYV-DSSGDVFLWSLWVPVTNTKFWVIGVEEQKIRCILCPVPTFIPFQVPLQLFALACKSDRDFRAVEICQLMES--IGLAIQYALAQKL Neucr2 P-NGALLASASFTTRKYLCLNLIGFVWTVVTVEFYDHERDFHFTDYDKACLNDKGSLFSVFYRPGEAVLAMSLSITVTTTGNYVRIYTLFGIPPMVTCASDYVLTMYTIENTVALPVKSVFFSDGDPCIY-DSTGTLLTLAVWVPLLDTRYFPIAVADHKFHCIILPLLSEFDFAVPLQLLAIECREDRGMRALEVVKLMTGRMIEAAGKVALGEKI Orpsp11 F-KSLYIAALAFVDKKYLAFNMLGSIYSVVHVEYHDRSRPYSFSNYSMASLCEHGAVFALYFKPDENIKAVALTVIAATDKKYLRFFTFSGFQKIVTMSGNQIFIVYMLYDELPISLEWIGFTEGIPATY-DSEGVGRILYQWVPVIDTTYWTVGMTEKHLLCVILPIVSEINLQVPLTLIMNACKEGNIQRALDLTSTLAS--VEKAVLIALAERI Pench1 P-NGSLLASLSFTTRRYLCLNLTGAVWTVVTVEFYDRERDFHFTDYDKACLNDNGTLFAIFYRPGEQIRALALSIVAVTSKDYVRVYTLFGTPQAVTCAADYIMSIYTVENTVALPLQSVFFSDGDPCIY-DSTGVLLVLARWVPLLDTKYWPVAVAQDKFHCIILPLLSEFDFQIPVQMLAIECREERGMKALELVALMNGKMLEAAAKIALEDKI Phybl2 K-VGDCIATLSLADRRYLAFDMFGVIYTIVNVEFHDLTKNFHFRDHHIAALGRKGAAFGVHYRPGEEIETVAINVIATTTAGFVRIFSLSGTQQVVSSVADMLMLMYRLMNSLPLNLTWAGFSELQPAVC-DSAGVVFILALWVPVFDGPYWPIGLLKEELMCLILPQVNSAELMMPTQLIQLACKAEKHDRVLDLSSALRS--IDAAIKIALAEHI Picst3 P-TSDHLAVLFVGTRRYLSMNSIGYSWVVVSVTFFDRGKDYHFVDYDLCSINEKGALFAIYYRKGEYITSVCVTITVATNFGYVRFYNLHGLCPVVTMISSVLFIIYSLVDLLPLKIKGIFFNENDPCIIPGIDDTLLILARWVPILNCHCWPLGVYDDQLNCLILPIPIVLNIELPIKLFGESCKDQRLNKALSVAKLMKA--LMAASKISLATKI Plicr1 A-NGVYLASLAWTDKRYLAYNMIGVVEVTVNVEFHDRSKSYHFTDYSLASIGERGVAFAVIYKPDQRVLGIAAGVVIATSEGDLTFLSGGGGEDFVGMVSEWAFVVGVVICMLPVPLKWMGITEGAPAIY-DSAGYLHVLATWARVLDTNYWPVGVNGNMFSCLILPLIQELPMQMPFQLIGLACKADKLPRALELTQLLPS--FDMAIRVALEEKM Polpo P-NGKYLASLAFIDRYFLALNMIGMIIKRIEIEFNEVSRKITFIDFDLASLGKSGAVFALYFKPNDKVIGVSIGIVACTKQRTLRIFTLSGLQDLITMSQDRLAVVVLYLNDLAISLTWIGFSDGQLTTV-DSNGIVRGLLQWSPIKDLKYWVVGLNDKSIYCILCPSLSPIPIS-PIRLFKNSLEDGNVQRCYELCQLLKS--LSIAIKLAISSKI Pucgr2 L-NGKYLATIVAANRRYLAFNLLGLVHVLVTVEFHDKGNGYHFTDFNLGSIGNLGLAFAIRYTPGESATCIACGVAVGTTLGYLRLFTGSGIQQIISLACEFIFVVYTLMDIIPLPLSWIGFSHSIPACY-DSNGVLSFLGRWVPMLATAYWPVGVSDSELSCIILPVIQDVHLQMPLKLIESCCKEPSLQKALDYSTYLNT--LDASMKISLQERI Punst1 P-NGVYLAALAWVDKRYLAYNTIGVIEVTVNVEFHDRSKSYHFQDYDRAAIGERGAVFAVIYKPGQRVLGVAAGVVVASSAGDLTFLSGGGVEDFVSLVAGWVLVISTLISRLPIPLKWVGVTEGVPAIY-DSSGMLHIMAVWSRLLDTNYWPVGVTKDTFMCLILPLIQEVALKLPFLLLQGACKNDKLARAIDLVKLLAS--FDTAVRVALQEKI Rhior3 P-NGYYMATLVFANRRYLCYNLVGAMYTIINVEFHDQSRNFHFTDFTMGALSEAGSIFALHFRPGEDVVAVAINVIAATSTGFIRIFSLSGIQNIVTLSADLALLVYLLLNKIQLSLAWAGFSETQAAIY-DSESILRILAAWVPVFNGKYWPVGVLRDRLMCIILPPVNEVPLELPLRLINIACKSERHSRALDLVNSLES--VDKAIRVALANSM Rhoto1 T-NGLYLASLAYIDRRYLAFNMIGYIYAVVTIEFHDRSIASKFDDYNLAALGELGAIFSLFYKPGEQATALAIGILVATSRGFVRFFSGAGLQEVVAMAADWAAIVYSLIDKVPLSLAWLGFTSNIPVMY-DSKGLISILGRWLPALDTNYWLVGVTDQQAHVIILPLLQEFDLQFPLQIIQTFCKADKLEAALDAVLLLAS--LIAAAKIALKERI Rozal11 P-NGRYVVYLVVTTKLFLDYTNIGMIVKRIDVLCHDRSKPQHFFNFDKGRISEHGSLFS-----TESVLAIAMDCYAGLNDRFVYVFSFGGKFDIVSISASFLMVVFTLINISNLYLKWIQVTDGVPCLY-NSNGELLL-CGYSPTILFKSWPIQVDGKSLKYILCPFMEPVDLIETIETIQSSMIKNKTKRVLDLCSFLKS--FNVACRLALIDKI Sacce1 PLRGTYIAALVLGTRRYLTMNEVGYVSTVITVSFFDVGREYHFEDYDLCFLNEKGTLFGIQYRPGERITSVAATVIVGTSLGYFRSFNQFGVPPIVALTAYRVFSVYSLSEPLPMSIKSLFFSSGDPCIF-GSDNTLLLLSKWLPILDSNVWPLALAYDTLNCILVPLPSEMEIRMPVRLFASACSDQNVEKALSLAHELRA--LTAAVKISLVKKI Salro R-DGRYLASIAYADKRFLVWNDTGFILSRIDVEFHNASRPIRLVDFTMGALTSSLVALALFARNGEEIECIAVGIAAATNKNYIRLYSNNGVVPVVTMAANKLMIIAVVLDNVPLTLVWAGFSDGLPAIV-DSEEVVRALFSWIPVAEFKYWVTGLSDNEIVCIICPVVSTVPLQMPIASISRSVQSQRWGRALDLTTRLGS--YDIAIKLALAERM Schco3 P-NGLYLAALAWTDARYLAHSLLGVIEATVTVSSFDRTPSYNFTTLRHAYIGERGVAFAVVYKPGTKVLGVAAGVVVATDEGDLTFLSGSGREDFVTMAAEWVFVVYSLIRTLPLALLWAGITTGAPAIY-DSAGYLHILASWARVLDTNYWAVGVTDSTFMCLILPLIQEIDIRLPFKLIQAACKDANIPRAIELTKLLHS--FDLAAKIGFTEKV Schpo1 S-NGMYIAALSFTTRRYLCLNLVGFIWTVITVEFHDETRKYHFVDFEMACLDHEGALYAIYYKANESPVTISLSVLVCTSAGYVRVFSRQGFPPFVACSSDTIITIYSIEDGVALPLESVFFSDGDPYIY-DSTGVLLVLAKWIPVLDTNYWPVTVADNQFHCILLPMFTEFDFRIPCQLIQKACLEERIERVYELTKTLTS--IAAAQKIAVAEKI Sorma P-NGALLASASFTTRKYLCLNLIGFVWTVVTVEFYDHERDFHFTDYDKACLNDKGSLFSVFYRPGEAVLAMSLSITVTTTGNYVRIYTLFGIPPIVTCASDYVLTMYTIENTVALPVKSVFFSDGDPCIY-DSTGTLLTLAVWVPLLDTRYFPIAVADNKFHCIILPLLSEFDFAVPLQLLAIECRENRGMRALEVVQLMTGRMIEAAGKVALGEKI Sphar ------MASLAVVY-------------------------------------------------------------------------------RCVPLCL----------------LEWMGFTPGLPITY-DSTGVVR------------------------------------------------------------------------------- Spipu1 N-SGSLLATLCMTDRRYLAFNMVGVIYTIVNVEFHDRSRPFHFTDYSMACLGESGACFALFYRPTESVKAIAITPVAATSQRYLRFFSYSGLQPVVTMTGDWLLIIYMLFHGLPISLQWAGISDGIPAVY-DSAGVLRNLFAWVPVLDSRYWPVEVMEDRLMCITCPLMSDIPLQAPFKLILTACKAEKVQRALDLCGSLKA--IDGAIKIALAERM Sporo1 Q-NGRYLVSIAFIDRRYLAFNMVGYIDVVVTVEFHDRSVSIRFDDYSMAALGELGAVFAILYKPGENVTLVAVGVLVATDRGFVRFFSGAGLQEVVTMAGDWAIVVCALIDKIPLALKWIGFTDNIPVMY-DSNGLLSVLARWLPALDTQYWPVGVNSNVAHVIILPLMQELDLQFPLQLISTYCKAERLEAALDAVLLLAS--LGAAMKISLSERI Stehi1 P-NGVYLATLAWTTKRYLTYNMVGVIEVTVNVEFHDRSKAYHFTDYHLGVLGERGALYAVHYKPDVHVLGIAAGVVIATSENELTFLSGSGIEDFLSMVAEWVFVVCTLYDKLPLRLKWIGISDGAPVMY-DSAGVMYIMATWVRLLDTNYWPVGVTKDTFMCLILPLIQELPLRLPFKLIQNACKSDRNPRVLELCRMLSS--FDMAIKVALQEKI Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr P-DGTLLAVVALINRRFLCYNFTGWIVARIQIDFADTTKRIRVTDFRLGTLNELGAFFALSYRPGEDPVAIGIGAAAATSANLLRIFSYAGLPPI-AVAGDALAVVYTVYSDLPLSLTWIGFSDGELVTT-DSAGVIRARA-WLPIGSLVLWMVGILESAAMVVRCPLLERRELKMPVRLFRQELLAGHRLRALDLFTRLTA--ANMALALALADRM Treme1 P-NGRYLASIVFTSKRYLGFNMIGVVDATVNVEFHDKSRGYHFQDYSMASIGEQGVIYAIYYRPGEEAVCVAAGIIVATSRGFVRFMSSSGIQDVVSMVADSVIVIYTLMDRVPLPLTWIGFTSDAPTMF-DSTGLLSVLARWVPLLDTTYWPVGVSATHMSCVILPLIQEIELQMPLQLVQGACKADNLQRALDLSRLMGT--IDAAAKVALQERI Trire2 P-NGVMLASLSFTTRKYLCLNLVGFVWTVVTVEFYDHERDFHFTDYDKACLNERGTLFSIFYRPGEAVTAMSLSVTVVTSANYVRIFTLFGIPPMVTCASDYVLTIYTIENTVALPLKSAFFSDGDPCIY-DSTGTLLTLASWVPLLDTKYFPIAVAENKFHCIILPLLSEFDFSIPLQLLAVECREERGMRALEMVELMTGRMMEAAYKVALGEKI Umbra1 P-NGNYLATLAFTDRRYLAFNMVGVIYTIINVEFHDKSRNFHFQDYSMAALGKKGAVFAIYYRAGEEVIALAVNVIVATSANYIRIFTLSGLQNMVAIAADLALLVCLVYNVMVTSIQWIGFSESLPASC-DSNGILSVLATWVPVFDGSYWPVGLLRDQIMCLVLPVISNIILQMPFRLIQFACKAEKSQRAIDIAKSLRS--LDAAVKIALAERF Ustma22 P-NGRYLASLAWSERRYLAYNLLGSVIAVISFESFDTSRNFRFSDICMADLAKQGILFAVFFKPGENVEAVALGAVVATSKGYLRFLSASGMQPVVTLAVRTALVIYKVIDVLPLAIRWAGYNDHQPAFY-DSNGTLFVLGRWVPSLDTKYWPIALTSSKLMVLLLHMIQELELQLPLQLIQLACKADKHGRALDAARALRT--LEAALKIALAERM Walse1 P-NGRYLASLAFIDRRYLAFNMLGVIHSVVTVEFHDKSRGYSFQDSSLCALGEEGALYAIVYKPGESASILACGVVVSTSKNYLRFFTTSGIQDVVTASAQYFVAVYDVIDTVPLAITWLGFSSDVPVMY-DSNGLLSILARWVPLLDTNYWPVGVTNTQLMCIILPLISELDIKIPLQLINTACKADKLQRALDAAAMLTS--IDAAMKIALQDRI Zygro1 PLHGLYLAAIILGTRRYLTMNNVGYVCVVITVSFFDIGVEYHFEDFDVCSLNENGALFALHYRPGERITSVSHTVFVGTSLGYVRIFNEHGVPPIVALTAYKVFAIYSLFEPLPLTIKNFFFSAGDPCVF-GIDNVLLVLNRWLPVLDANVWPLGLNYDMLNCILVPLPSEMEMSIPIRLFAGACTEQNNEMALSLAQDLRA--LNAAIKIALVKRI [Cluster2333.fasta_al_trimmed; alignment length = 83] Allma1 GIERNKRCLLAYDKVRALTWSPAEARFAEKYAELLTSFKP-PKELYICVRVVKDCGEIFTETGANTQHFVR-RTDVERLITQG Ashgo11 CMERNKRCLLAYEILDAIAWSPYEQEYLREYSQLISDLTP-PSDVFIDVRVLKDAGEIQTEYGKDSQFFVR-QADVERLIQQG Aspfu1 CTRRNKRCLLAYEKLEELCWSPEEEEYFRQYSDMLAAYKP-PRDLFIDVRVLKDAGEIQTEYGSNPTASIE-SGADKCDVLQG Aurde31 GMRRNKRLMLAYDKLRDLYWSPHEVDFLRQYHDMVVVARP-PKELHVLVRVLKDIGDVHTEMGKGQRFHLR-RTDIEHLIVQG Batde5 ALARNKRCVLAYDRLVEMLWSGHEAQFVNGYKTLASEFRP-PNAVFVEIRVIRDCGEIATDDGPGAQLFVR-RCDVEDFILSG Botbo1 AIRRNIRCLLAYDRLKDQYWSPYEVDFLRGYNSLIMEYRP-PKDLHVLVQVVRDCGTIHTENGKGQRFMVT-RSDVEHLLVQG Botci1 CMRRNKRCLLAYDKLEEMVWSPEEEEYVRQYSDLLAAFKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIAQG Caeel AMCHIRRCMMAYNRIRSFRWCDAEIQFFNEYSSTLARFQP-PKSLFVQVRALEDYGEFETSDGKDSLHSLP-RQDCEMLIRQG Canalb1 SMRRNKRCLLAYDKITEFCWNHHEQDFFKQYQDLIMEFKP-PTNIFIDVRVLKDGGEVTTEYGKDSQFFVR-KSDVERLIQQG Cangl CMERNKRCLLAYDILDNIAWSHYEQEYLKEYGELITELKP-PSDVFIDVRVLKDAGEIQTEYGKDSQFFVR-QSDVERLIQQG Capow AMQRNKRCLLAYLQIEQVRWSPFEQQYMSQYNQILQTYMP-PKDLLAEVRCLTNEGEIVTENGKNSTLFLR-RSDVDMLIRQG Catan2 AVDRNKRCLLAYDKITNLVWAPPEAAFADKYVELLTAYKP-PKDLYVTVRVVKDCGTIVTEAGLGSMHFLK-RTEVERLITLG Cioin SLQRNKRCLLAYQKIRALRWSPKEIEWFTKYNRALANYMP-PQNVHIEVRCVEDKGELELDDGKNSLHYLP-RSQCEHLIRQG CocheC53 CMRRNKRCLLAYDKLEEYCWSPEEEEYVRQYSDLLAAYKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIAQG Coere1 TAGRNKRCLLAYEFLRSLLWSPEEQNFSREYARLNSAYRP-PRDMFIEVRVVRDCGEIVTESGVGTQHYLR-RSDIEHLLTIG Conco1 ----------------------------------------------------------------------------------- Conpu1 ----------------------------------------------------------------------------------- Copci SINRNKRCLLAYSMLQNLYWSPHEVDYLRQYNASLMEYRP-PKEIHVRVRVARECGVVQTENGPGERYVVR-RADVENLIVQG Croqu1 TARHNKRVLLAYNAILDAYWTPAELDYLRAHSNLVSDLSP-PKDLFIQVECVKELGEVAIGDGVGSRYFVK-HGEVERLIEGG CryneH991 AARRNKRCMLAYGGIKERWWSPQELDFLRGYNSLMLDYKP-PGELMVDVRVVRDAGEVFLDSGKGQRFRLE-RAQVERLIIQG Crypa2 SMRRNKRCLLAYDKLEELVWSPQEEDYVRQYGDLLAAYKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIAQG Debha1 CMRRNKRCLLAYDKIDEFSWNHAEQEYYKNYQHLITNYKP-PTNIFTDVRVLKNGGEVQTEYGKDSQFYVR-KSDVERLIQQG Dekbr2 CMRRNKRCLLAYQQIDNLVWSQHEQEYLNRYNELVSEFKP-PKGVFIDVRVLKDAGEIQTEYGKDSQFFVR-QADVERLIQQG Dicdi SINRDKRCILAYNRIKEYRWSQNEIQFFSEYDKILTEYNP-PKELYIEVRVIKELGEVVLNSGLNTTHFLK-RSDITNLVKNG Dmel ALQRNKRCLLAYRRIKALRWCEPEVTFFNNYSKSLAAYMP-PKSLYIEVRCMEDYGKFELDDGKNSQHYLP-RAQVESLVRQG Enthi LRQRLKDLYEIYKRIENIRWTNDEIQYFKQYCKIVGEYGP-PINNYINVRANVTKGSIYTTNGSEVQCVLR-NSTVDSLIHLG Falba ----------------------------------------------------------------------------------- Fomme1 TLMRNKRCLLAYNFLKSLYWAPHEVDFIREYNTMVVDFRP-PKDIHVLVRVVRDCGVIETELGKGQRFMVR-RADVEHLLVQG Fusgr1 SMRRNKRCLLAYDKLEEQVWSPQEEEYVRQYSDLLAAYKP-PRDLFIDVRVIKDAGEIQTEYGKNSQFYVR-QGDVERLITQG Galma1 AINRNKRCLLAYDRLRDMYWSPHEVDYLRQYNGSVMEFRP-PKDLNVLVYVVNDCGTIQTELGKGQRFMVR-RADIEHLIVQG Ganpr1 ALRRNKQCLLAYELVKQLAWSQQELEFYESYCDLLRDYSP-PRDLFIHVRALVDLGEIVTESGKGQQDYVL-RTDVEHLIAQG Gloin1 ----------------------------------------------------------------------------------- Hisca1 ----------------------------------------------------------------------------------- Klula1 SMERNKRCLLAYEMLDSMVWSHAEQEYLKEYAQLLTELKP-PSDVFIDVRVLKDAGQIETEYGKDSQFFVR-QSDVERLIQQG Lacbi2 AINRNKRCLLAYDRLRDLYWSPHEVDYLRQYNSSIMEFRP-PKDIHALVRVVRDCGVIQTELGKGQRFMVR-RADIEHLIVQG Lenti61 AILRNKRCLLAYEFLKDLYWSPHEVDFLRSYAASLLTLRP-PKDLQVHVRVVRDCGIVYTELGRGHRFLVR-RSDIEHLIVQG Malgl1 QAYRNKRCLLVYDWLRARVWDPAELEWLRSYAALVALYKP-PDDVMIYVLVTRNVSDVETERGVGERLYVR-RDEVEALLLRG Mellp23 TARHNKRVLLAYNAILDAYWTPSELDYLRSHSNLVNDLSP-PKDLFIQVECIKELGEVSIGDGLGSRYFVK-RGEVERLIEGG Mnele ALEHNRRCVLAYNKITQFRWQEHEKQWFNKYNKSLANYMP-PKSLKIQ-----DYGELETDSGVNSEHYLP-LSECEHLIKQG Monbr KLERSARAMVEYHKLQDLRWSESERNFANQYNRVLGSYTP-PKEATITVRVLDTIGEVDFGDGKGTQHLMR-RADAELLIRQG Morel2 ----------------------------------------------------------------------------------- Mucci2 SVKRNKRVLFAYNKLKEILWGPTEQKFLDEYGDLVNSYKP-PVDLFIEVRVLRDAGEINTEYGKGNQFYVK-RTDVESLIKAG Mydma CLERNKRCLLAYMHLKTLRWCEQEIQWFATYSKMFTNYMP-PKSLFIEVRCLMDHGELVTEDGKNSQHFLP-TSQCEHLIRQG Neucr2 SMRRNKRCLLAYDKLEELVWSPQEEDYFRQFGDLLALYKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIVQG Orpsp11 ----------------------------------------------------------------------------------- Pench1 CMRRNKRCLLAYEKLEELCWSPEEEEYFRQYGDMLAAYKP-PKDLFIDVRVLKDAGEIQTEYGKNSQLYVR-QGDVERLIAQG Phybl2 AIKRNKRVLFAYEKLKELSWGPNEQKFLDEYTDIVNSYKP-PTDLIIEVRVIKDAGELITESGKGNQFYVR-RTDVEGLIKSG Picst3 SMTRNKRCLLAYNKIDEFCWSHAEQEYYKNYQDLLMDYKP-PTNIFIDVRVLRNGGEVQTEYGKDSQFYVR-KSDVERLIQQG Plicr1 AITRNKRCLLAYDRLRDMYWAPHEVDFLRAYAASTIAFRP-PKDLHVHVRVVRDCGTIQTELGKGQRFLIR-RADVEHLVVQG Polpo SILRNKRIILAYERIKEYRWSPNEVNFFTQHDKLLTEYHP-PKELFIEVRVIKEFGEVVLASGLHTTHFLR-RSDVGNLITQG Pucgr2 TARHNKRVLLAYNAILDVYWTPVELEYLRAHSTLVHDLAP-SRGLFIQVECMRELGEVAVGDGVGSRYFVK-RSEVEQLIEGG Punst1 AIERNKRCLLAYDRLRDMYWSPHEVDFLKAYNASVMDFRV-PKDLHVLVRVVKDCGVIQTELGRGQRFMVR-RADIEHLIVQG Rhior3 ----------------------------------------------------------------------------------- Rhoto1 ALNRNKRALYVYDVIKDKFWTTTDETFAKGYADLCLAFKP-PKELMVDVRVVRDVGEVELLSGKGAQYHLS-REDVESMIVAG Rozal11 ---------MAK---------------------------P-PKDLFIQIRVLKDCGNLLTTSGKDSQHFVR-RTDVEHLISQG Sacce1 CMERNKRCLLAYDILDSMAWSHQEQEYLKEYCDLITDLKP-PSDVFIDVRVLKDAGEIQTEYGKDSQFFVR-QSDVERLIQQG Salro ------------------------------YNNLLSKYMP-PKELDVQVRVLEDAGELDTETGRGSEHLLR-RADAEQLIRQG Schco3 AINRNKRCLLAYDRLRDMYWSPHEVDYLKQYNASVMEFRP-PKDLHAVVRVVRDCGTITTELGQGQRFTVR-RADIEHLIVQG Schpo1 SSIYNKRCLMAYQRLRQYCWSTYERDYLTRYSELLAAYKP-PKNLFIDVRVLKDVGDIETEYGKNSQLHVR-ATDVERLIAQG Sorma SMRRNKRCLLAYDKLEELVWSPQEEDYFRQFGDLLALYKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIAQG Sphar CMMRNRRCVIAYKRLRRARYGAPERDFFLAYDEILNDYSP-PGSLFIDVRPLKNVGTIMTENGMNKQENVRWSTEIEDFIRQG Spipu1 ALRRSKRCLLAYDRILDTLWSSSEADFITGYTGLVSEYRP-PRDLFVEVRVLKDCGEVMTENGKNSQHYLR-RTDVEPFITAG Sporo1 ALTRNKRALYVYDTIRDQFWTTFDEAFAKGYSDLCLQFKP-PKDLMVDVRVTKDMGEVELLSGNGKQYFLP-REDVEAMV--- Stehi1 AINRNKRCLLAYDRLRDMYWSPSEVDFLREYNASIMEYRP-PKDLHALVRVVKDCGVIQTELGKGQRFMVR-RSDIEHLIVQG Tapde11 ----------------------------------------------------------------------------------- Thetr ALLRNKRIMLAYQYLQNLRWSALETGFFSAYDRLLGDYMP-PKDLFIEVRVVQDAGTIITEAGRNSTHYLR-RSDVEHLIRQG Treme1 AARRNKRCLLAYTGIKERWWSPQELDFLRGYNNLMLDYKP-PGEIMVDVRVVRDAGEVVLEGGKGERFRLA-RSGVERLIVQG Trire2 SMRRNKRCLLAYDKLEELVWSPQEEDYVRQYGDLLAAYKP-PRDLFIDVRVLKDAGEIQTEYGKNSQFYVR-QGDVERLIAQG Umbra1 TVKRSKRVLMAYNRIKQIIWGP-EIDFAKDYSELMTSYKP-PDDLFIEVRVLKDAGEVQTEYGRGSQFYVR-RTDVESLIRSG Ustma22 IISYNKRSLLIYDLVMSHLSSAIEHDHLRRYSDLIHRTKPLPTDPLVTVKVNRDLNDIWLTSSKDQTLTIN-RADVRPLIARG Walse1 CAQRNKRCLLGYNKLRDLYWSPTEVDFLRGYSSLITQYKP-PKDLHISVRVVRDAGLIETQGGVGQRFMVR-RSDVERLLVQG Zygro1 CMERNKRCLLAYDILNSLAWSHQEQDYLKEYTDLLTELKP-PSDVFIDVRVLKDAGEIQTEYGKDSQFFVR-QSDVERLIQQG [Cluster2336.fasta_al_trimmed; alignment length = 262] Allma1 KQLVRRTMRTFFEPKETIIMDFLTSTPLILDMDLGKVLGVTKE--VGHMVARLVTHRLLRKEQKEDKK-G-ATKPSRNVYFLDYKQFLDVMKWKLYTMQQITKQKINMDARGYECPCGRQYTILQAQSRDADDTTGADELGRLSEQQRPLLDLIRQ-CDTILPRYSVLAVSAEGGVATVTVEISRD----EIERKRLEEA-EKLRKE-NELPKWHRYSMVTGLAHLSDHSGH-DHDDLMSVPLSKVGEAERMSVDEYEAYYD Ashgo11 KSLLQFVVRGFYSNSYVLVLDAIMFHSVLSEEDLAHLLGIKPE--LRSLITTLVDDMLVASHSQQE-A-Y-NSRSLRYYYYIKYPQAIDAIKWKVHQLVSKMKDDLNSAPQGYMCPCHAKYSQLEAISSGKKSKEKQMRLNRLMDQVQPIIDYLKK-IDDSIEENTFLD-NESSRRATLHVNITTADEQ-AQKELQERKA-EEKRKQ-NALPSWHEKSAIGKYAKLAEEEEE-EEEEFEDV--SNTKQTNEEESD---AEFE Aspfu1 NTLIRTVVRAFYETRQILIVDALFIHSVLHAEDLAFLLGMQKD--LRKLCAKLREDRLIAVSTRAERD-G-STRPVREYYYIPLHPVIDAIKFKVSKLTSTIKAQYSEERKEYVCLCGAEWTELDVLSAEGIDRTGHEKNSKLMAQLDNMLKLLKQ-IDSVIPPNDFEAVRGNLQTSALEISLTSTKSA-AEQAEEAARK-AALEKQ-NALPVWHTHSTVSTYAEMEDSDDE-FDEEFEDV---------KEESDEDDEEFE Aurde31 RRLVQNVARCFYDARFIVVLDQLVRHPVLKDDDLAGRLGLQKE--LGKLTATLCNHRLVSKYQQNEKE-G-GFRAVRSYYYIDYKSFCNVVKWRISQMRRDIDKKLELDNKGYICPCSHCYTPLEADQSAAGVVGSHDRMQRFNAQMAAIREGLKQ-SESVIPAFDV---ASADGKEGLDIVLDADDEE-SIRREREAEA-AAKRQQ-NAMPSWHLKSTVSGYASLQASDED-EKPSLSYLPFSQITEEDLMTPDEYTAYFE Batde5 KHLVSLIARAYYETRHVIVLDLLTLNAYLRDDQLASALGVNKD--LQKICGILRVQGMLKVETRWEDA-Q-PHTKAKSYYYIDYRQFVNVVKYKIYKIGKMIEKEVEITQMPYKCPCIKEFSALDMLSETTGSKNSSAAYTRFMNESRPIVELLKQ-TDNIIPDS--PKIKEISGNQ---IVVELENAE----------------------------DTLGAYSNL-SPDDE-DEE-FETV--------------------- Botbo1 RHLVQHVSRAFYESKLVVIMDQLARHDVLKDDDLAGRMGYNKD--LGKAIAPLVNDKLVSSYHQNEKD-ANVNRSYKKYFYIDYRNFCNVVKWRMAEMRRLIDDKLELANKGYLCPCGKNFSILDADRETEDITGKQDRMQRFNAQTQWIREGLRK-TEEMLPAFDILAIAGSSGIQKLSVEIIGDDSE-ARRLAKEEEA-QAKREQ-NALPTWYTHSTINGYAQLADAAAA-DEPPARHLRLSQVTEEDLMTPEEYSAYTT Botci1 QMLVRSCMRSFYDTKHILVIDALVIHSALRDDDLAYLMSINKE--LHKLCGKLKEDRFLAVHSRPEKE-G-QQRPIRTYYFIDYRATIDAIKWRVFQIDKAVQGNTDDERKEYFCPCKSEWTMFEVLD---NNRGGHEQSSKLNAQFKFITDLLPK-IDQVIPANTFTAVRGLDNTTSISVTLTNGPTA-ADIAAEQARK-EKTAAQ-NALPQHFTHSTITGKAAQ-ETDDE-EEEGFEDVAAPVIKDE---EESEEDMEFE Caeel NTILLMVVKNFFSSEHFIIVYHIMRAQCIREENLKARIQFDKM--LRQLLASLKAEKLVKERTITQNE---NNRTVIIFYYINYRAVLNVVRYKIDHMRQKLESREDTNRAHYRCGCQSSYDMLEINRTVVPSRTTRTAVARFNEQMTPLFSHICA-LNGILAPHLLINY-------AVFVDLNAD---------------KGPVEEAKIMPEWLKDNAIG-EEEETKIEEPPAKQIKMEVPLSQITPRNEMSELEKESYCS Canalb1 RSLIRFVSRGFYSTPYVLILDAVLRHSVLSEDDLIHLLGIKKE--LRSLCNRLVDDRLLTNHIQRE-N-G-QQKYVRTYFFIHITEAIDSIKWKVHSIVNVLKQEMFGNPQGYVCPCGNKVSQLDAISSSQQATLKQERLEKLMKQLDPIIKFLKI-IDETIRDNDFSN-AQAMQNATLHVSI-TADEN-YEREQMEKENRRQKLEQ-NALPSWHSNSTVGQYAQLA---------D------------------------- Cangl KNLLKFVVRGFYGGSYVLVLDAIIYHSVLVEEDLKQLLSINTE--LGPLIARLRSDRLVSTHKQRE-P-P-NSKSVRCYYYIKYPHAVDSIKWKVHQLVQRMKEDLNSEPNGYMCPCLTKYTQLEAIQSGKKNKEKQDKLNRLMDQIQPIIDYLKK-IDDSIEENTFLG-NDSSRRATLHVNITTADEI-VQRQLQERQA-EEKRKQ-NAVPEWHQQSTIGKYAALAEEEEE-EEEEMEDV--------KNKDDD-MDIEFE Capow KHVALLAVRAFYPPDCVVMLDTILRYNQVTEEDLMKFFKLDDKASLNKTIAVLRSNRFIKEVKIKQ-----QKYSK---YVVDYESLVNVVKYRLHKINQLLRQQTDMSMAKYKCACGRGSTEVDIVKIKLSHA-IGARESRFNEQIRQLVLKIKE-VDKVLPQAPE--SGRPAGGDNMAVQL---DSS------------KAPLKA-KAPPIWMQKSTIYVLREMQ--ERE-RRHHINR-PLHEITDEAQMSDDEYNQYYI Catan2 KRLVKLTARTFFAPPEILIKDRDIHRMC----------RLVRR--L------------LRREHRQKKS-A-ASRMA--LF-VDVLSFLL-----YELTGRVERT--EVEKRGYECPCLRKYP---------------PELRILNNQIRPLLDLIEQ-CR-----------------EPIREEVVVE----VDDADEEARRVKAAQQKKNQLPDWHRYSTVTGNQTLSDADSD-DEYGFED-PLEQIGDDDRMTPEEYTQYYA Cioin ------------------------------------LLKFDKQ--LRVVLNKLKNDKFLKSRSYVEQE---DGKVTQNYYYINYRTVANVIKYKLHHMHKRIETRESNNRPSFKCPCGNTYSDLEVNQESASNQDARTSQARFNQQMEPLYKMLKE-VENILSQDILLNI-------EVIIDMGG----------------KVEEEK-KEMPRWLTESTV--QER--HDNHD---------SYHEVANQELMTEAEKDEYIR CocheC53 KQLLRTVVRMFYETEHIVIMDALCYHGALPVADMTIILDAGKH--VSKVAGKLREAGLCSSYTQHVRQ-G-ANKASREFFYIDWRHAVDSIKYKIYKIDEGIKRDATTEKPEFKCLCKSTYTTMQALD---------DTPAKFNKLFGPLIETMKE-IESMLPAMEPTAVKGI-DTEKINVQIGSSQNE-KQRMAEKARQ-EKISMQ-NQLPSWHTQSTVIKEAERRDDEDE-DEDEFEDVPTPSAAATNGGDESEED-EFE Coere1 QKLVDVVARTFYKDEFVLALDYLNRHEVDV---LARYLRVKKE--VYRIYNELEKHKLVKLMVRTDRR-G-KQR----YYYLDYKHFVDVVKWRMYKLQVQVRMKMEQQNLGYDCPCERHFTVLEAVPQ------SQKEFSRIMDQFKTIIDLLRK-TDSILPAPTPLGIARDTGADTV-IEFAPD----ELARIRESEL-EKKLRQ-NALPAWHIWSSVSGLAQLAERIEK-ERKEAAAAPIAYVTPESNMSTDEYATYWN Conco1 KKLVFLVARLFYEPRCVIILDIMTHVDSIKDEDLSAMIKIPKE--LHKICGKLLEDKFIQMFTRQEKK-A-DQRPVKTYYVIDYRKIVDVVKWKLYQVKIKVNEKVAKESSGYKCPCEKKYNVFDAIKETEGLN------ALFNEQTRPIIELLKQ-TDDILEDVNLLDISKDTGSTKITVVI---DEQ-KTKEAQEAEN-ERKRLQ-NAMPVWHVKSTVRPYTMLN----------------HEQTENNDNSNREDSAQGS Conpu1 RILVQHVSRGFYEPKFSIVLDQLARHPVLKDDDLAGRMGLQKE--LNKLMAVLNNDQLVQVYRQNEKE-G-AQRSVRQYYFINYKHFCDVVKWRIAEMRRIIDSGLELDNKGYICPCNKSYTSLEVDKNAENVKGSKDRMQRFNRQIRFIIEGLRK-TESMIPSLDVLKIAGSSGNDGVGIMLSMDDEL-TRRQERDAEA-AAKRQQ-NALPAWHLKSTITGYASLADEEEE-QKPNIQYLQFSQVTEEELMTPEEYTTYFE Copci RLLVQHVSRAFYEPKYIIIMDQLARHPVLKDDDLAGRMGLQKE--LNKVIAVLSNDCLVKVYRQNEKE-G-AQRSVKQYYYIDYEHFCNVVKWRIAKMRHKIDHKLEIDNKGYICPCKQSFTPLEADKNSASVQGSKDRMMRFNHQMRFIREGLQK-SEAMLPKFDVLKVAGAGSSDGIGIVMVQEDEE-RRRKEREKEA-EQKRVQ-NALPAWHLKSTITGYASLADEEED-RKPAIEYLPLSQVTEAELMTPEEYTAFYQ Croqu1 RQLLQYVARAFYEVRHILLFDQLVRKEAMKDEELATRLGVGKE--VAKAANLLIRDQLVSVYLRAEKP-G-ASKATRTYYYIDYKHCVDVIKWRMWKISKVLDDKQVIDGQGYVCPCKTTYSTLDISGNDIEVQKNKDRMQRLNAQSTLIKKTLQK-ADKVVPAFDILAVATGGAKATVSVQMAQEDME-AKRLLKEQQA-EAKRQA-NALPIWIAQSTVSGFANLQ-HDPK-RSPSDSTSDLSSVTEEHNMSPEEYSLYYN CryneH991 SDLVYQVAYSFYDVPYIIILKMLVQYNVMTEIDLGQRVGLSNE--VRKYMGTLHLHRLVKRHVNREAPIG-DTRTRVHYWYLDYREFANVTKYRLAMMRKGIDERIEVGQRGYQCPDGRVYDTLDVGHDQENNSSLQDMMQRFNIATAPIRDALKA-VEVVLPGTNVVSVDGQEGGKKFEVVI--G----DDEAK-EKLA-QAQREQ-NALPEWYTHSTVTGYELL-----D-EEDDVEEVKIEDVTEDELMTSEEYEAYAQ Crypa2 KQLVRSCARAFYDVRYVLIVDALVIHGALRDDDLGYLLNITKD--LHKLCYKLQQERFLQIHVRQEKE-G-AVRPSRTYYYIDYRQTIDAIKWRVYKLGKDMQVPTASERKEYVCPCKADYTQLEVLS---RTSAGHEKVTRLNNQLKFITDLLLR-IDNVVPDNNFTSVKGLADTKKIDIKISTSPTE-EEKEAERLRK-EKIAQQ-NALPAWMANSTVSGKREQEEDDDD-PDDE----TA---GED---DDDEEGLEFE Debha1 RSLIRFVARGFYSKPYVLILDAVLLHSVLSEDDLIYLLSIHKE--LRSLCNKLVEDRLLVNHIQKE-N-A-QQRLIRTYFYIHTTEAIDSIKWKVHSIVNIIKEEMYGNPQGYVCPCGKKVSQLDAISSSKQASLRQAKLEKLMNQVDPVISYLKK-IDDAIEDNTFSN-LSSLQNATLHVSI-TADEN-YEREQQEKEERRQKLQQ-NALPSWHSEGTVGKYAQLA--------ED------------------------- Dekbr2 FHLLRLAARSFYPHQCVLILEALMFHSVLYEEDLLKLTCMHKV--FRSFCNRLLDDRSITSYTQKE-A-G-QYRWLRTYYYIHYLEAIDSIKWKVHCLVKFVKDEIFNDPQGYVCPCHAKYSLLDVPSTDLEAQKGQEKLERLMAQLEPIIESLKK-IDTMVDDNNFAG-NDGTSAATIHVSI-TADED-IKRERMQREKRNEKLRQ-NASPSWHRESAVGGYAQLREEEDE-EEEE----EKHDATKDDMDDEDIDDAIFE Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel KQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLRFEKQ--LRARITTLRTDKFIQIRLKMEGP---DGKAQVNYYFINYKTFVNVVKYKLDLMRKRMETEEATSRASFKCSCSKTFTDLEADQAAMPKKDSRLMLAHFNEQLQPLYDLLRE-VEGILAPEVLVTIGGD----AVI-------------------------ER-KSRPIWMTESTVI-HEKQPDDEKDIENSKIPDVPLDQLDDNAQMTPQEKENYIH Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba KRLVRITARMFFQSAHVVILDALLTQRC---QELSAMLHLSNR--IQTEMGALKGLVKIEKDARE-KS-K-AGQMQIDLFRIDCLNFIVLIRWKVEMLNRQLDS--EENKKIFRCNCDNTYTFRGAMF--------QPNSERMLSQLKPLLNLLEE-VQKMLPPT--IGLSGS---FSVRVATMEE----LAK--------QASGKKRIHL----------GMPNLS--------------P----------TPDSYTGFIA Fomme1 RLLVQYVSRAFYEPKFVIIMDQLARHPVLKDDDLAGRIGLQKE--LNKLMAVLLNDRLVQVHRQNEKD-G-AQRSIKQYYFIDYRHFCNVVKWRVAEMRRLIDSTLELDNKGYICPCKATFQPLEVDRDEESVRGSKDRMERFNWQTKFIREGLRK-SEAMLPAFDVLKIAGADGKAGISVMMSIDDEA-TRRREREAEA-EAKRQQ-NIMPSWHLKSTISNYASLE-EEEE-RKPNVAQLPFSLVTQEEKMSPEEYTAWYE Fusgr1 ITLVKSVMRAFYQTREILVIDALILHEALRDDDLAYLMSINKD--LHKICGKLREDRFLVVHTRSERE-G-NPRPSRTWYYIDYRSTIDAIKWRVYTIDKEVQGTTASEKKEYFCSCKAEWTAMEVLD---RTSTGHEQSTRLNDQFKFISELLPK-IDAVINECDFMAVKGLANTQSIAVNISTSLTE-AEKAAEQARK-EQIAKQ-NALPSWMSNSTVTGKAEQ-EDDDD-DEDEFEDVKEEDDG------EDSDEIEFE Galma1 RLLVQHVSRAFYDPKYTIIMDQLARHPVLKDDDLAGRMGLQKE--LNKVIAVLSNDSLVKIYRQNEKE-G-AQRSVKQYYYIDYEHFCNVVKWRIAKMRFIIDSTLELDNKGYICPCKQSYSPLEVDKNAESVLGSKDRMQRFNNQMRFIREGLQR-SEAMLPAFDVLKVAGSDGTEGVGVMMAMDDES-TRRLERDAEA-EVKRQQ-NALPAWHLKSTISGYASLADDEED-RKPNVEYLPYSQVTEEDLMSPDEYTAFFE Ganpr1 VELVRRVTRAFYTHPHILIMDLIAAKGELRDEELVAATKIPKE--LARFCQKLKEDRLLSSESKET---NINQKILRNTYYIDFIEFINAVRLRIALVNRRIQRDIAEERQSFRCPCRRTYDLTDAQRDKALSKMTHETYQKFARQTEKLVELLSK-TDSMIEAHKR---------RKIAVLLRDPNSSLGSDGKIKSEAGPAKVQE---LPIWHQFSTVTGLANYQSDAES-DEEDFSDV--------NTVADEDDDDDFE Gloin1 ISLLMRVARAFFQTHHIVILDQLTKQEAMSDENLAKGVGLNKE--IHKFCGTLKEARLIKTFTKAEKK-A-EQRAIRTYYYVDWQQVVNVIKWKIFKIREMVGDRMEQENKGYLCPCKKVFAPLDVHNNAENVKGSEKLHGRFMEQSKPIIDLLKT-IDKLIPVSSIVQYAQDTMQD---IVVVFQDNE-TSKIERQAEL-EKKRQQ-NALPAWHVRSTVSGYANY-EIDDD-D---FEEVDLESSHRYRLRTDDGYGKYSE Hisca1 SSLIRTVVRAFYETRHILVIDALFIHSVLHPEDLAHLLGMQKD--LRKLCARLREDRLIAVHSRPERD-G-QTRPVREYYYIPLYPVVDAIKYRVSRLTSIIKAQYTAERKEYVCTCGAEWTQLEVLSGTGADRTGHEKNSKLMAQLDKMLKLLKQ-IDSVVPENDFAAVRGISKTSSLEISLTSSKSA-AEQAEETARK-AALEKQ-NALPVWHTHSTVKTYAEMASSDEE--EDEFEDV--------AVSDEDEDDEEFE Klula1 KALLSFVIRQFYPNSYVLVLDAIMFHSVLSEEDLAHLLGIKPE--LRSLITVLLEDRILARHSQQE-A-V-NSRSVRYYYYIKYPQAIDAIKWKVHQIVAKLKDDLNSTPQGYICPCSTRFTQLEAIASGKRSKEKQGRLNRLMDQVQPIIDYLKK-IDDNIEENTFMG-NDNSRKATLHVNITTQDEL-YQQDQQEKQA-EEKRKQ-NALPAWHEKSTIGEYAQLAMDDDE-DEDDFEDV--TEKKQTDDEDDD-GEGEFE Lacbi2 RLLVQHVSRAFYEAKFTIILDQLARHPVLKDDDLAGRMGLQKE--LNKIIAVLHNDCLVKIYRQNEKE-G-AQRSVKQYYYIDYEHFCNVVKWRIATMRHKIDSSLELDNKGYICTCKQSYAPLEVDKNAESVQGSKDRMQRFNHQMRFIREGLQK-SEAMLPAFDVLKVAGSDSKAGIRVMMAMDDEI-TRKHERDAEA-DLKRQQ-NALPAWHLRSTITGYASLADEEED-RKPNLEYLPYSQVTEEDLMTPDEYTAFFE Lenti61 RLLVQHVSRAFYEPKFTVVMDQLIRHPILKDDDLAGRMGLQKE--LNKIMATLETHKLVRSYRQNEKE-G-AQRSVRQYFYIDYQLFCNVVKWRMAEMRRIIDQGLDLESKGYMCPCRKTFQALEADRNAENVLGSQDRMQRFNRQMRFILEGLRR-TEGMLPAFDVLKIAGASGEDAIGVVMSVDDEE-TARAERDKEA-AQKRQQ-NALPKWHLTSTISGYASLAAEEED-VKPDVDYLPFSQITEEEAMTPEEYTAYFE Malgl1 RRLAQVIARLFYEDGHILVMDQLVSIAAIPAEVLARRIGMQRD--LTSLATKLVQDRMISVHRNQERE-GPFQRPIRTYFYMDYKHFLDVTKWRMMAMRRHIDTKLGLDNKGYVCPCRHSYSTLEVAHDAEDVRNSKDTLTRFNEQLSVVQRSLRS-VEGVLPSLDIAALAPGSVSPAVRIEMEHDHEEVEKEKLRTLEE-ERQRVQ-NTLPSWHLASTVSGAS--QTVDVD-DTNDLMS-ETDDVGDD---GEDEMDDMED Mellp23 RLLLQYVSRAFYEVRHILLLDQLIRKEAMKDEELAARLGVGKE--LAKAANMLIRDQLVSVYLRAEKP-G-ASKATRTYYYIDYKHCVDVIKWRLWKISK------VIDGQGYVCPCKTTYSTLDISGNDIEVQKNKDRMQRLNSQSTLIKKTLQK-ADKVVPAFDILAVATGGAKAAVSVQMAQEDLE-NKRLLKEQQA-EAKRQA-NALPVWIAQSTVSGFAKLQ--DPK-RSPSDSTCDISSVTEEHHMTPEEYTIYAT Mnele RQLIKMVSNTFYRTEEALIIDILLKHPCIREDDLIELIKLDKH--VRASLETLRKDKLIRSITKGEEEVGPGGGALFNHYFISYKVFIDVVKYKLDRMRKKIDQDDQQNCQFHLCKCDLRFSDLDVKDAQLKSLQDRSSVSLFNEQTKTFTEYLKI-TDNTLSEDLLYNL------SSIKVNLAGE---------------KAETQK-KELPVWLAESTVI-SEMMTPVPED---------PLTEVEGDSKMTDKEKELYDQ Monbr QELARKAVRAFNEPTCVVLLDLIIAQGGVKDAVLEELTQLEST--IKGPLSKLRQDHMLQEHAMTD---PLDARSRATYWFINYPPLINALKYKLLRLRHMLDEEAARFQSNYVCPCSRSYTDMDYAEDQSKADRVNQLMSRLSEQTVEFQKLLQY-ADTKVSEKLTRHVSQRKRPDKSVVSFVND---------------EAREQR-KAQPLHLQQNTVLLSAMLASDELDGDESDFEGEDIDDVTDEAEFDAEQIEIYNE Morel2 DQLVYRVCRAFYEPRYIVVMDVINKLKQVKDEELAASVRLNRE--IHKICGKLKEDRLIKDLTKLERK-P-DQRPINTYYYLDYKIFVDVVKYKIHRMGKELDSVMEVESAGYRCPCHNAFAMVDVVNAVEDDDQGQEMKTKLREYIRPIVDLLKQ-TDSMI-EQY-LAFAEDGGQE---IQVVFEDNDKAAKKARENEA-MKKRQQ-NAVPSWHAWSTVSGYENL-QQQEG-EET-FDTVPLLEVTEESQMTPEEYEAYYN Mucci2 KALVARVARAFYDPKYIAILDALNNAPPVREEDLVFTLKMTRD--IHRICGKLKEDRLIKMANRMERK-Q-DQRLIKNYYYIDYKEFVDVVKWKMFKMQTLVRDNLESENKGYICNCEKQFTPLDVLSNAENVKGSQQILTKLREQSQPIITLLKQ-TDSIIPSSYILAIAQDTGAD---IIVDLQDNE-AARRAKMEEA-EQKRQQ-NALPVWHQQSTISGYESLS-LEED-RDV-FETVPLNEVQEERNMTTDEYKAYYE Mydma KRLAKTVAYALYEPEQIVTINILTKYPCIDEDTLMEKLQFDRQ--LRQVLGRLKNDKLVKQRVVKEQQ---DTGVLYNFYFINYNLFVNVVKYRLDHMRKKLENEEAKNRPSFQCECSKTFSDLEVDRSYIKNYSSSSSLAKFNEQLETIFKLLRQ-CENILAPEVLIDI-------KIQINVGAE---------------QAEAKVIKELPVWLSQSTVFEYE--SDSEPD------SDIPLSEVNDDSKMSDSERDIYYK Neucr2 KTLIRCVMRAFYSTQEILIIDALVQHSCLRDDDLGHLMKLGKD--LHKACAGLRDARFLVVHTRPEQA-G-KTRPQKTYYYIDYRQTIDAIKWRVYKTDKDMQGIASEENKEYVCPCEAQWSQMEVLD---REAPGHQQLSRMNNQFKFMTDMLQE-VDKVIPECNFSAVKGLANTKTMQVIISTGDAE--QAEAEKKRQ-EELLRQ-NALPEWITSSSVPT-------------------IS--VKDEEGGDEEEDDLEFE Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 KTLIRTVARAFYETRHILVVDALFLHSVLHAEDLAFLMGMQKD--LRKLCAKLREDRLIGVSTRAERD-G-STRPVREYYYIPLHPVVDAIKYKVSKLTAIIKAQYSEERKEYICLCKSEWTELDVLSAEGMDSTGHEKNSKLMAQLDNMLKLLKQ-IDAVIPPNDFDITRPNAKTAALEISLTSSKSA-AEQADEAARK-AALEKQ-NALPVWHTHSTVNTYAEMEDSD----EEDFEDVPDPDAKIEEAEESDEDDEEFE Phybl2 KGLVARVARAFYDPKYIVILDELNNAPPVREEDLVMTLKMTRD--IHRICGKLKEDRLLKMATRMERK-Q-DQRPVKTYYYLDYKEFVDVVKWKMYKMQTTVRDNLESENKGYICSCEKQFSTLEVLSNAENVKGSQQVLTRLQEQSQPIIHLLKQ-TDSLIPSSYILAVAQDTGAD---IIVDLQDNE-SARRQKLQEA-EEKRQQ-NALPVWHQRSTVSDYESLSGHEEE-DDE-FETVPLNEVMEDRNMTTEEYKAYYE Picst3 KSLLRFVTRGFYSVPYVLIMDAVIKHSVLSEDDLIHLLSIKKE--LRSLCNKLVDDRLLVNHIQKEPN-G-QPKFVRTYFFIHVTEAIDSIKWKVHYIVNQLKQEMFGNPQGYACPCGKKVSQLDAISSSQQATLRQEKLEKLMFQVDPIINYLKK-IDESIQDNDFSNMSSSLQNATLHVSI-TADEN-YEREQMEKERRRQKLEQ-NALPSWHSNSTVGKYSQLA--------ED------------------------- Plicr1 RLLVQHVSRGFYEPKFTIVLDQLARHPVLKDDDLAGKVGLQKE--LNKLMATLSNDKLVQIYRQNEKE-G-AQRSVRQYYYIDYQHFCNVVKWRVAEMHRRIDSTLELDSKGYRCPCKKAYSTLDANKDEETAKGSQDRMQRFNWATRFITEGLKK-SEAMLPAFDVLRVAGSGPNSGVGVLMSMDDEA-TRKMERDAEA-AAKRQQ-NALPAWHLASTVTGYASLAQDDED-QKPSIEYLPFSKVTEDELMTPEEYTAYYE Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RLLLQFVARAFYEVRHILLFDQLIRKEAMKDEELSARLGMTKD--LAKAANPLIRDQLVSTYMRAEKP-G-AYKATRTYYFIDYKHCVDVIKWRMWKMNKVLDDKQVIDGQGYVCPCKKTYSTLDISGNDIEVQKNKDRMQRLNSQTMTIKKNLQK-ADQIIPPFDILAVATGGAKAAVTVQLAEEDLE-AKKRLKEQQA-EAKRQA-NALPVWIAQSTVSGFAKLQ-NDSK-RSPADSSAPLLEVTDDQLMSSEEYTQYAQ Punst1 RKLVQHVARAFYEPQCIIILDLLSRYPVMKIDELAGRMGVGKD--LNRLCG---EHKLIRVYRQNEKE-G-ATRATKAYYYVDYENFCNVVKWRIKQMHATIDSSLELDQKGYICNCSKPFTTIDAAKRNGSSDTS-DLMQRFNAAMFHIREGLRK-TESMLPAVDILKIAGANGTEGVGVVLSLDDEE-TKRKQREAQA-AARQQQ-NALPSWHLKSTISGYASLADEDED-VKPNVELLAFSQVTEEEMMTPEEYTAYFE Rhior3 ---------------------------------------------------------------------------------MDYKEFVDVVKWKMYKMQTLVRDKLESENKGYVCSCAKTFTPLDVLSNAENVKESQEVLTKLREQSQPIISLLKQ-TDSIIPSSYILAVAQDTGAD---IIVDLQDNE-AARRAKLEEA-EQKRQQ-NALPVWHQKSTISDYENLSILDEE-QET-FETVPLNEVTEESNMTTDEYKAYYE Rhoto1 KLLLQKVVRGFYGPRQAILVDQLVKKEVFPADELSKRLGMQKD--VTKIAHRLIEDQLVQIHRRSERENG-AMKALRGYYYLDYSRATDVIKWRMYKIQQTVDVELELDAQGYVCPCKATYTPLDAANNEEDVQGKKERMQRLNKQSKSIVDLLKK-LEQALPRFNVAAAAEANGTAIVKIHMAGDDEA-KEKARREREV-EEKRAQ-NALPSWIAQSTISAYANLE--TPA-LSPP---IPFSQVTDEGDMTADEYSAYWE Rozal11 RELVQVVARKLYSPEHCVLLDALIRFQTLKDEDLSDYLKITKD--VNRIAAKLKNDRLIRSDAKPERV---GGKPLRTFYILDYKLFVDVVKYKISMLRKRMNEDIDVTSKTYKCPCEIIYSIMEASKNSVIPEVTQEMNAKFNEQFAEIIRLLKQ-TEDLIEKLHVSNITDVSNRAPVDVRIETD----LALQQRTAEEQERKAQE-NKRPEWMEISTVSGKLSAGRDDED-PNDLVEHFPLEDITEAEKMTPEEYSEYYK Sacce1 KNLLKFVVRGFYGGSFVLVLDAILFHSVLAEDDLKQLLSINTE--LGPLIARLRSDRLISIHKQRE-P-P-NSKSVRVYYYVKYPHAIDAIKWKVHQVVQRLKDDLNSEPNGYMCPCLTKYTQLEAVQSGKKNKEKQDKLNRLMDQIQPIIDSLKK-IDDSIEENTFLG-NDSSRRATLHINITTADEV-AQRELQERQA-EEKRKQ-NAVPEWHKQSTIGKYAALAEEEEE-EEEE-----NAKPNDGDDDDDDEMDIEFE Salro KTLAQKVVRAFYDEVAVVVMDMLVRHACVKEDDIRETLQLQRV--IKTALSALEGDRLVKQMDVDD---SIDERKRAKYWYIDYEAVVFVVKYKLDRIWHQINIDAKLSSTVCECPCEAQFSDMDLSE---TAAELNSVMTKMNTQTRVFTDLLQQ-VDEILSETVLLNVSRSLPQPKLHTKLYQSPFE-ETYSIRIVPP-GAKRKKYKPQPLWTRGTTVLL-----VRGEDLVHDRFWEVGASEDGDDDDDDDDDDDDDAD Schco3 KRLVQYVARTFYEPKHIVLLDLLVRNPVIKDDELAGMMDMKKD--VQKIAADLANASLIKLHRQNEKD-G-AVRASKTYYYIDYIHFCNVVKWRVWRMQKKIDSTTELDNKGYLCTCRQTYTALEVDKGA-GAEGGNTRLQRFNQQIHLITSGLRKVDEAGLPAFDVLRIAGEGGSAAVGVVLAAEDEA-AARAARDAAA-DARRQQ-NALPAWHLRSTVSGYAGVSDDEED-DAPRV--VAYSAVTEEEQMTEDEMTAYVE Schpo1 QRLIKMIMRAFYETRHIIFMDAILRHSALTDEQTALLMGIPKE--CRFIAGKLREDRLLAIQSRTEKE-G-QQRQYTTYFYIDFCSTIDSIKWRMHQLVKTVEDRMDFDSKGYVCPCNKKFSSLDVLSESAEMMSSQKRLGKLMGQVNGIIDALKR-VDEIVPQNNFVRLSTSSPS----ITVDFSDKETDEKRERNCDK-QVKAAQ-NILPEWHATSTISGYATLRD---E-EDDDFLDV-FNEDDED-----DEDEADFE Sorma KTLIRCVMRAFYSTQEILIIDALVQHSCLRDDDLGHLMKLGKD--LHKACAGLRDTRFLVVHTRPEQA-G-KSRPQKTYYYIDYRQTIDAIKWRVYKTDKDMQGIASEENKEYVCPCEAQWSQMEVLD---REAPGHQQLSRMNNQFKFMTDMLQE-VDKVIPECNFSAVKGLANTKTMQVIISTGDAE--QAEAARKRQ-EELLRQ-NALPEWITSSSVPT-------------------IS--VKDEEGGDDEEDDLEFE Sphar TKLVGDLVAGG-----VIVVEEIAREQQ-------------SR-----------------------NK---APRKPANWYYIDYEKMVNMAKWKVDRVGKMLETKARKDNQGYHCPCDMKYSALDVGEAEVKQDADEGAISRFNKQISKLTDCLSE-CDKAIPDKRMMAFAANSSD----------KAE-AMRTAYEAAA-AKKRKE----TQWSGRDYLGDERQMESDDLD-EEADGSDTTLSSITADKRMTDAEYNTFFD Spipu1 RKLVALVARAYYEPKHIIVLDLLSRVNSQRDEELARALRVQKE--LHKVCGKLKSDGLVKVEARGEEN-R-PQRKIRSYYYIDYKHFVDVVKWKIYKIGKMIEKEVQMANMPYKCPCNKEFSALDFAMST----GVSEKYTKFMNESQPIVELLKQ-NG------------------------------------------------------------------------------------------------------- Sporo1 RLLVQKVSRTFYGSKGAILIDQLIQKEAYRDEELGKRLGMPRD--VSKIAHRLISDQLVQVHRRSEKP-G-APKASRTYLYLDFSKTVDVIKWRMYKVQQTIDVKLELDAQGYVCPCKSAYTPLDAANNDEQVKGNKDRMQRLNRQTKSIVDLLKK-LERVLPRFDIAAQAAAAGTPSVQVQIAGDDEA-IERAKREQEL-KEKRAQ-NMLPSWIAQSTIEKYASLESGTPD-MRGEVGGIPYSQVTEDSDMTADEYSAYWD Stehi1 RLLVQHVSRAFYEPKFIVVMDQLARHEVLKDDDLAGRMGLQKE--LNKIMAVLENDGLIQV--QNEKE-G-AQRSVRQYFYLDYQHFCNVVKWRVAHMRRTIEHGLELDNKGYVCPCGKSYSTLEVDKNAESVRGSQDRMQRFNWQMRYIVEGLRK-TEPMLPAFDVLKVAGSSGSDGVGIVLSTDDED-TVRKERDAEA-AAKRQQ-NAMPSWHMQSTITGYASLADFEED-KKPNVDYLPFSAVTEEELMTPEEYTTYFE Tapde11 -----MISR--------------------------------------------------------------------TYYFVENRDAIDAIKYRIHRLVRVIEEQSDFESKGYVCPCQRRYGALDVLSESMESKVSQERLGRLQKQTQQLVSTLKQ-IDNSVPDNDFTRTTTAALD----VRIDYNNQQ--DSAEEKARK-SAQAQM-NALPEWHLQSTVSGYKALRDGEEA-EEDDFEDV--------------ESEDEFE Thetr AELTRKVMRAFYDGPSIVLMDMLLAKAPIKDDDLRELMKFQKQ--LTMYLKPLELERMVTKKRI--KE-G-HEYTINDYYWINFKGVVDAVTYRFVKMKKQMEEAI------FECKCGKKFGDMEAATAKTEHASLLAREKRLNEQLDPIGRLLEQ-TQQFVRQA-K---SREAGGWMVA-------PA------------VPPPSE-TDPQIKVSRFAIANLDEVRDAGRA-RRPSARRWPASTTTSTAARARTTRTRALI Treme1 HNLVYQVAYAFYDAPYIILLRLMVHLGVSTEKRLAEICQLSQE--LRKYMGMLLVHRLVKRHVGKEDPEE-KMRIRVIYWYLDYREFANVTKYRLAVMRRSIDDKVEVGVRGYLCTCGRTYDPLDLGHDDTTGDKV-DRMGQFNLATAPIRDALKS-LEGMLPSVNILPVQATEGRKKVQIVLGSG----RERLEAERAA-EAQRVQ-TSLPVWHTQSTITGYANLALVKQE-EEDEDED-PLGEITEEAHMTPEEYQV-GR Trire2 VTLIKAVMRAFYSTRDILVVDALILHEALRDDDLAYLMAINKD--LHKICGKLREDRFLTVHTRSERP-G-NPRPSRTWYYINYRHTIDAIKWRVYNIDKEVQGTTVNEKKEYFCSCKAEWTAMEVLD---RNAGGHEQSTRLNDQFKFISELLPK-IDAAIPECDFMAVRGLANVQSIAVNISTSPSE-AEKEAERLRK-EKIAQQ-NALPSWMSNSTITGKAEQ-EEEEE-EDDEFEDVAKADSGNE---EEDEDELEFE Umbra1 KTMVARVARAFYDPKYIVVLDALNKIGEVKEEDLSINLKLTRE--LHKLCAKLREDRLVRIVQKQERA-P-DQRAVKTYYYIDYKQFVNVVKWKMYKMQTSVRDTLESENKGYVCPCQRTYPALEAVGNAENVKYSQEVLARLREQCLPIISLLKQ-TDSLIPASYVLAIAQDTGAE---IIVDLQDNE-AARRAKISES-NKKRQQ-NALPVWHQQSTISAYDSL-LMNDD-EDTGLEVVPLHEITEDLKMTTEEYQAYYE Ustma22 RRMAQIVARIFYDDRHIVLMDQLVSITVLPADVLAHRLGIQKE--LAALSSKLLEDKLICTFRRNERD-TITNRSVRTYYYLDFKLFLDVTKWRMMSIRKKIDTRLELDNKGYVCPCKKSYSTLEVAHEAEDVKRSKDSLMRFNEQLSTLLGGLRR-TEGILPPLDVASSAPPSTVPALQVDLASNAAEAARRLAKQKAE-DEQRKQ-NALPAWHLASTVSGASLQT-VDEE-EFDDFEPVVTVETGED----EDGMDDFED Walse1 KSLVQHVGRSFYESKYYIILDQLIRKEAMQDGEIAGRIGLTKD--SSKLIAKLISDKLVFHYRRNEQP-P-NPRPLKTYYYIDYQQFIDNVKWRMWRIRKAIDDKLELDQKGYVCPCQKTFTPLDVLHESDGVKGSQDMMARLLMQCRHIIAGLKL-TEDMLPPFDILAVAGAGSSSQVKVQIVADHDA-EQKKKLEQEA-EERRTK-NALPEWVLRSTISGYSNYN------------------VTQQNNDSEEEDDDDFE Zygro1 KNLLKFVVRGFYGGSYILVLDAILFHSVLAEEDLKQLLGINTD--LGPLVARLRSDGLLSMHKQRE-P-P-NSKSVRVYFYIKYPHAIDAIKWKVHQVVQRLKDDFNSEPNGYMCPCLTKYTQLEAVQSGKKNKEKQDRLNRLMDQVQPIIDYLKK-IDDSIEENTFLG-NDSSRRATLHVNITTADEM-AQKALAERQA-EEKRKQ-NAVPEWHKQSTVGKYATWAEAGEE-DEED----TNAVPKQEDDDDDD-VDIEFE [Cluster2348.fasta_al_trimmed; alignment length = 199] Allma1 ARAY-HVTYFGSDHFSVRVLDNLLRPFDEIAVVTGRQLHL-NALSQYA-RVRSLKRWDLAVVVSCPYFIPPYILDMPSGAMNLHPSLLPKYRGAAPIQHAIWNNDQETGISIIDLDPNRFDAGAILAQQK-VNFLADQGSALLLDVICNTRARKITKEIFWDEVSATEVWNRWRAI-GIGVTRVKPVSRKEQGADFVNG Ashgo11 AAPL-NVLFFGSDQFSAHSLRALAAIVGDIQLVTGRYLQATLPVVAAA-RETRDDLLNLLVAVSYGQLIPAELVRSP-HSLNVHPSLLPRYRGAAPIQHTLLNGDSTTGVSVQTLHPTRFDEGAIVAQTPELDQLGLRGADLLARVVADSRAPKLPPAVDWSTDSAARALAKLAAL--LVCSLLQFQGFKPELPKFMSS Aspfu1 YDPL-RILFCGADEFSIASLKALHERISSIDVVCGR-----VPIKAVA-TEDTFKGWRRLVAVSFGLFVPPRILNAKYGGLNVHPSLLPDFRGPAPLHHTLLAGRTKTGVTLQTLHVKHFDHGVILQQTP-ANIVAPKGAEILLDGIRKIHAAKIKPEIDWVNWTWKDISRRNRVL-GIQIYQMKVEGEQN-----ADG Aurde31 RSRF-RVLFMGRDEFSCEIFKALYDIWDEMHITTAHKTVVCAPLRLIG-EQECWRSYALLVTASFGKIIPNQILDASMQKLNVHGSIVPALRGPAPVQWAIARGLTETGVSVIELSPA-IDRGAILGAQA-ISTLADIGGTLLVRVLRDSHAPAVTARVDWASWDATHIDRMHRAI-SVAATRVQTLNRSATGADWWNG Batde5 SSRY-NILYFGTDNFSVACFKSLLTIIKNIQVVT--KAKIVVPLKRFC-KQKSLAGWDIAVVVSFGYFLPRHIIHEKIAAINVHPSLLPKYRGSSPIQYTILNGDNETGISVIELSPKRFDAGRILKQTH-INMLAIHGGDALIDTIEHTYAPRLEKSINWNKQKAEQIYSLHRAI-SIGIRCLQMPTKRKQHAAFNNG Botbo1 REPF-KVLFFGRDEFSCSVLEVLHKIIQGIWVITGRRGRSLAPLKLLS-QESELASWHLLLTASFGRAIPTSILDLPSQRLNIHPSLIPEFRGAAPMERTIEAGLTETGVSVIQMEDI-FDVGDVWGQRP-VPILAKEGAELLIQVLRDTTARLIRPRVDWSTWDAPKVERLHRAF-SVHVRLLQRGNRGSLVAEWWNG Botci1 SAPL-RILFCGSDEFSCESLRSLVAGIASIDVLVGRGMKEIVPLKKLA-KEDTFTGWNLVVAVSFGLFVPPRILNSEYGGINVHPSLLPQYRGSAPLHHTIMNGDTITGVSLQTLDPHKFDHGAILSQEG-FDLVTPKAASLLAKGIRDKLAHKVKPIIDFEEGLSINVERKFRAL-GISIDKYKIPR-QDR--NCSNG Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 HDPL-KIAFFGSDNFSVASLNKLIQKVDSVHVITGRYMKTVLPVGKFS-SQTSQEIRNLVIAVSYGRLIPSTFIQHKYGGLNVHPSLLPKYCGSSPLQYALLNDDKFTGCTVQTLHPTKFDHGDIIIQSSEIKKFGEIGGDLLVKSIDQSMAPKIPKAVFWNKYSAREIKRLYDAL--VLVERIKMQAQEEESPKFIGT Cangl TKPL-NILFFGSDEFSAYALRSLVKVIDSIQVVSGRKKSVLPEIVQYA-QDSNEEMLDMIIAVSFGKLIPNGLIGRP-YSLNVHPSLLPRYRGSAPLQHTLLNQDQYTGVTVQTLHPTKFDHGSIVAQSDPLDQLGIVGGNLLADVLEKSYAPRIKTEINW-NDSATDLLNRLQTL--ILIKKLQFEACAIETPQFMKK Capow ERGL-RILFFGSDRFSALSLKALVDPIASIEVVIARDAAVTSSVAQVA-KLATDPIWDLGVVISFGAMIPERVLRSRLGAINIHPSLLPKYRGAAPIHRAIMAGDTETGVSILTVTPHKFDVGSILLQK--------LGAQMLTECIQNVMARKLTPDLNF-TNPAAQIANQCR---------VTFEKRSKQSAQFFHG Catan2 -REY-HVAFFGSDTFSVRVLSHLLSPIDSLTLVTGRGLQV-GPLAQFA-TDKSLKGWDLAVVVSFPYFLPRALLDRSSGAVNLHPSLLPKYRGAAPIQYAIINGDQVTGVSVIDLDPKRFDSGAVLAQNR-VDLLADRGAEAIAGVLRDTHARKITSAPTWSSVNARLLWNKWRAF-GVRIKEIKPANKKVMSAAFVNG Cioin QPPY-KILFFGSDCFSLVTLKKLHNLITKLEVMC-------SVVHEFA-TN------DLGVVVSFGKMMPQRIIDSSLGMLNVHGSLLPQLRGSSPVSRAIQGGITSTGVSIFQIKSDGFDHGKILSYSSPVQKLAYIGADLCLEVLWNSYAPKINVQINWESMTPETILKNFRAF-G-----TKLLYGKILSSDFYNG CocheC53 SSPL-RILFCGSDDFSVASLRAVVDLIDSVQVLHGRGLKTLVPIKQVAVEEDTFTGWDLVIAVSFGLFVPPRILALRYGGINVHPSLLPDLRGPAPIEHTILKQRKYTGVSIQTLHPQHFDQGTILAQTP-PKQLADVGAQMLVDVLESDHAPKITKAVDFETDTMAAVLAKHQAL-GGNAKLVRILA---------DG Coere1 VDGL-KVLFFGTDDFAARTLSCMMDPIDHIEVVCRRGKKEVSTAGTRA-VLRVMSNWDIGVVSSFGSFLSARIINSPKGMINVHPSLLPLYRGPSPIQTALLNGDKYSGVTVQEVHPKRYDAGNILAQLP-FALMGHLGGGLVSKVLGQTSTQMYDLNIIWETMTAEQIMRMHRAFYGIHVTRFQVASKQARDAQFNAG Conco1 RNKF-NICFFGTDQFSEYSLEKLLNRINRIDVVTGRGYKVVL--KTYA-EKKKFGNWDLAIAVSFGYFIPTRVLTKPQGGLNVHPSLLPKYRGAAPIFHTLINEESETGVTVQELSTEKFDAGKILNQKI-FEKLGILGADMLVETIDNTHAKKFGKEINWLEDNLGLLMKKHRVL-G--VDQVHVSNKRKIHVEFLNG Conpu1 TRPF-DIVFFGRDEFSCTVLSQLHAVWENISIVTGRRGSIVSPLKLLA-ESPEFRTWHLLITASFGRILPAPLLRAPGRALNVHPSLLPLYRGASPIQYTLMNGDTRGGVSIIDMMER-IDAGGIWAQEE-MDDLAERGGKLLVNVLRGPRAPSITAQVDFSLMSRDQIIRLDRAI-SLAIGTLKEQNRRAVTAVWWNG Copci SEKL-KVLFMGRDEFSCLVLRELYAVWQELVVVTGRRASQVSPLKLLA-QDPEFRKWHVLVTASFGRILTRKHLSRPSRRLNVHPSLLPQYRGPAPIQHSIMNGDPETGVCVIEMLDAVIDAGDIWASMK-MDALAVEGGKLLVGVLRKP-APMIHLQVDPAKMVAEQVCQKWRAI-AFAISSVKPAGKPVLPADYWNG Croqu1 -----KILFLGSDSFSCAVLKELI-LWDEIHVVTGRGLKNV--------H-PTQKSTAMGCTSSFPYFVPKELINQPSHCLNLHPSNLPLYRGPAPIQWQLADRVDRLGVTIQDLSPHGFDLGDVLAQQA-VSLLALIGATLMCKVLKNTKARKISQSQDW---NLAILKTRYLGM-G--------------------- CryneH991 KEPF-RILFCGSDDFAVASLKAVHEVWSSIDVVVGRGGKH-PALRLYA-EQTGLKTWHVLLTASFGHIIPLRLLKLPIQRLNVHPSLLPRWRGAAPVQWTIANGDEETGVSVQTLVRYAVDAGDILGRVEGIPSLAEAGGKLLVDVLRKTVAPKITHEIHWEKHTAEAIDRLHRGF-TIEVQEIKMASKKALGIEWWNG Crypa2 SAPL-RILFCGSDAFSCASLTALHDLIESIDVLVGRGLKRIGPLFHLA-HADTFTGWNLLIAVSFGLFVPPRILFSAYGGLNLHPSLLPDLRGPAPLQWTLLANRPGAGVTLQTLHPTEYDRGHILARTP-TESLAPVGAALLADALQQ-------------------------------------------------- Debha1 KKGL-SIAYFGSDQFSVRSLKKLVEKVSSIDVITGRNLKTFVPIGEYC-ERSSHDIMNLAIAVSYGKLIPEGFLNSKYGGLNVHPSLLPKYSGSSPLQYALMNDDSFTGVTIQTLHPSKFDKGDIILQSDPIKKLGEYGSNLLLNVVDNSLASKIKPVIRWDLLTSRKIKRLNDAL--ISIGKLKFQYCGEEDPTFMNY Dekbr2 --MI-RVGFFGADEFSAGCLKAISPIISHLDVITGRGLQHLFPVAKFA-SAKNVDFGDLCIAVSYGKLIPSSFLRSPYGGLNVHPSLLSRYCGAAPLQRALLNQDDVTGVTVQTLHPTEFDRG-AILARDSYEELSRRGGKLLYDISLNSYAKKVQPSINWSQYDTFKIVRNFNTL--VSAGIIKVESLGSVSGRMSNP Dicdi SPPY-RILFFGTDNVSLPILKSLHELVKELQVIC-------ELVEEYA-IENGMKGFDLAVVVSFGHFIPKSVLSKKYGGINMHPSLLPRHRGAAPIYHQILSDDDNVGISVIELHHERFDCGKILKQI---TNLVELGSECVMSTIQDTLAPKVNRKLEWSTQTINEIWILYKAF-SIGITKLFEEGKKNTVKEFLFG Dmel YHPP-KILFFGTDNFSLPSLQAL--CGDRLGVVT----SFKC-VRTYA-EK--LQKWDLGVVVSFGHLIPGSIINGPYGMINVHASLLPKWRGAAPIIYAIMKGDASTGVSIMKIEPHRFDIGDILAQRE-VASLASLGAELLVDTINNSYAPKITSKIIWSELSAIEIYTRHRALYGLEVLQLRVEGRKPMSADFNNG Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -RVIPSLLFFGSDNFSVSFLRRIIE-IGEIQVVSNR-----NNVTPLK-QFKTLRNWSLGIVASFDYFITPPVLAGEHGAINIHPSLLPQWRGASPLQHAVISGARSSGISIQEVHPRRFDAGNVLAARP-F---MAAGVPLLAEVLADSLAPKFPPGLAW-DRPATHYDRLARGV-GVP-RALAPERRAKMSPVFRSA Fomme1 SGPF-SILFLGRDEFSVLVLDQLHKVWNDIAIATGRNGSKISPLKLRS-LEAAFKDWQLLVTASFGRMIPDRILHLVSRRLNVHPSLIPFYRGPAPIQHTIADGRSETGVCVLEMKEK-ADVGEIWAKKS-LDKLAIEGGKLLVSVLKNSYAPFTTQEVDFHSWDALKVERMYRAI-GLYVPVVKQQDKKLLSADWWKG Fusgr1 SDPL-RILFCGSDEFSCASLKAVHELIESLEVMAGRGFSSLVPCKLLA-EEGTFKGWNLVIAVSFGLFVPPRILGSKYGGLNVHPSLLPDLRGPAPIHHAILRGDSHVGVSLQTLDDKSFDHGTVLYQTP-HNLLAPVGAQMLVQGLRDVHAPKISKAIRWSSWKADDIVRAIRVL-GIRVKKVKVEG---------KP Galma1 ---------MGRDEFSCLVLQELYQVWREIVIATGRRGSILSPLKTLG-EKREFKTWHLLVTASFGRILTSKMLSAPTRRLNIHPSMLPSYRGPAPIQHTILNNEQETGVCIIEMLKK-IDAGSIWARQT-MDELAIAGGKLLVSLLREPRAPFITAKVDFPTMTADDIHRHFRAI-SLGVSTVRPEGKAARAAEYWRG Ganpr1 ---------MGSDEFSLPSLQKLAATVSELEVVV--SLDVTV--RSFA-KSKTLKGWDLAVVVSFGYFLPLELIASQHGAVNVHPSLLPKYRGAAPIQHALLHGDTETGVSIIEMHPTRWDAGRILRQSR-LDQLADLGAVNLVETLRYSKAPKVTKSINWTTMTRNHVFNMYRAF-GLGLRVLRPQYKKDMSADFANG Gloin1 SQAY-QILFFGSDKFSVASLKALINFVKSIEVVVGRGYKEIV--KIFA-QEKSLEGWDIGVVVSFGYFLTPSILESSKGALNVHPSLLPKYRGASPIQYAILNNDKITGLTIQELHHEIFDAGKILRQIT-HSLLATKGAELLINTLRNTKAPKIKKEIKWSQISAQQLEQLYRAI-SITFNSVKVEGKKEVSTDWING Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 GNPL-KVLFFGSDQYSSHLLSALHSDIDSLQVVTGRYLSEVVPIMSVN-DSTRSDLLNVLIAVSFGKLIPKQLIEKDGKAFNIHPSLLPRYRGSSPIQYTLLNRDEFTGVTIQSLHPTKFDHGEIIKQTAPLDQLGLKSGELLQQMIRESLAPKITTEINWKNERKLRLLAKNDAL--IGTNVLQFEGFALEPVTFVNR Lacbi2 E-RF-KILFMGRDDFSCLVLKELYALWQNILVATGRRGSLLSPLKILS-QTPEFRQWHLLVTASFGRILTTTQLDAPTRRLNVHPSLLPAYRGPAPIQHTLLNGEQETGVCVINMLKK-IDAGGIWTRVV-CETLACEGGKLLVSVMRDSHAPKISMALNFETMSAENIVQRYRAI-SLSVPRVKQDGKSLLETEWWNG Lenti61 P--F-KVLFFGRDEFSCLVLKEVLAVWQSIQVVTGRRGSQLSPLKLLA-EESAFRTWHLLVTASFGRILSNSLLSMPSRRLNVHPSLLPAYRGAAPIQHALMDGQDETGVCVIEMTEW-IDSGAIWASER-RDTLARTGGQLLVSVMRDPRAPLITADVNFETMTASRIAMIYRAI-SLSVPEVRQQDRHLLKAEWWNG Malgl1 ----------------------------------------MSPVKQLA-EQEGLEAFPLLITASFGHRIPTSMLSHTSLAINLHPSMLPDLRGAAPLQWAIARQYTQTGITVQQLHPTHFDRGGILKQVI-VEELAPRGAELLVDVVARTRAPKLAPRIRWDAWNAAMIDARMRAF-G-GITRIQTRGKPARLSDWWRG Mellp23 -----QLIFFGSDSFSCVVLKEII-LWDELHVVTGRGLKNV--------Y-KISSSSELGCTSHVTECYERHLIKQASHCLNIHPSHLPLYRGPAPIQWQLANQINPVGVTIQDLSPDGFDLGDILAQQS-ASFLGRIGGSLMCKVLQNTKARKILQTSDW---DLSKVKSRYLGM-GISKKHLEHQHKNTY------- Mnele SSSIKNIIFYGTDTLSTAVLSKIHT---NISAVT-------SPVYQFC-QKEVFRKSHLGVVASFGHMIPGRVIRSSHGFVNIHPSLVPKYQGAAPLPHTLLNGDKKYGVTVLEALPRSFDQGRILRQSH-FSYTAGNMADVTHAFLRESPAPRISKLVCPHLQTADQIFNISRCL--LGVSRMVLPFKPIVSAQFYRD Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 QDKV-KILFFGSDSFSVPHLEALIQIIERIDVVS--KKSKRSPLTLLA-KAGGFDAWDFGVVVSFGWFLPDDVITRKKAGINVHPSLLPKYRGSAPLQRAILNQDQTTGVTVQLLDPNEFDAGKILAQAE-VALLAKKGGELVVDVINNTKANKISREVQWSTWTAARTERLHRAN-GLGVKAVQFEGKKRLSADFHNG Mucci2 SDKL-RVLFFGTDDFAKTHLQALVKCIESIDVVCGRKLEKLT--KGVA-ESKTLQDWDVGIVVSFGYFIPPHIIASKNGAVNVHPSLLPKYRGAAPIQHAIMYGDAETGVTIQELDDREFDAGRILAQEH-VEKLSAIGSRLLVDTMRNTKAPKIKKEMDFVNMSAWQAEQLHRAI-GVACTRLKMQNKGAVSADFVNG Mydma KNRL-KVLFLGTDNFSVGILNALNQGISELDVISVKNKTILPPVLMYA-EK-----WDVAVVASFGDFIPAPIISQ--KSINVHPSLLPRWRGAAPVIHTIFNNDRTTGVSIIEVSKHKFDVGNILYQIE-TVLLMNKAASIMPYVMSHTLAPKVSNLINLQLLTCEVVSRIQRAL--IGVKNLHVECKKEISADFYNG Neucr2 SDPL-RILFCGSDVFSCYSLKALHALIKSIDVMVGRGYKEIVPIQNLA-EEDTFTGWNLIVAVSFGLFVPPRILNQKYGGLNVHPSLLPDLRGPAPLHHALLNRLSHTGVSLQTLSPQTFDAGTVIAQTP-LDLLAPLGADMLVSSLQKTHAPKITKALHHSA-ADAALRARVCGA-GLRVGKIKVEG---------KG Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SDPL-RILFCGSDEFSIAHLKALHARISSIDVVCGRGLKQFVPLKEAA-SADTFTGWNLVIAVSFGLFVPPRILNGKYGGLNVHPSLLPNFRGPAPLHHTLLAGETTTGVTVQTLHLKHFDHGVILSQTP-PDFVAPKGAQMLVETIDKKHAPKIVPEINWANWTLADINRRNRVI-GLRINRMKVEGEQD-----AEG Phybl2 NKKH-DILFFGTDEFASNHLKALILSIGNIELVCGRKMNELT--KALA-TLKTLDNWDLGVVVSFGYFIPPHVIETKKGAVNVHPSLLPKYRGAAPIQHTILGGDEVTGVTVQELDDKAFDAGRILSQEK-VNKLSDVGCKLLVSTLRKTSAPKIKKDIKFDVMTAWQIEQLHRAI-GIGFTHIQAESKKTILADFVNG Picst3 --PL-NIAFFGSDSFSVQSLDRLYRRILSIKVVTGRNLKAYLPIGDYC-KKSTEDILSLAIAVSYGKLIPAKFLESEFGGLNVHPSLLPKYSGSSPIQYTLLNDDRTAGCTVQTLHPTKFDQGNIILQSKEIIRLGAIGSDLLVQVIDESLAPKIRPSIKWSIKSSLQIKRMEDAL--IGVRKLKFQACKEEVPVFLKA Plicr1 QEPF-KILFFGSDVMSCHVFEELFAVWQSVSIGTRRRGDTLSPLRLLG-ESSAFRQWHVIVTASFGRMIFDPLLKLPSRRFNVHPSLLPDFRGAAPIQHAIMRGDAETGVCVIDINER-VDTGDIYSQIP-ATVLAREGGRLLASVLRDPLAPMINDHVDFLTMSAHEIVRRHRAI-SLRVPEVKEEGRNRISAEWWNG Polpo PPPY-KVLFFGTDQVSINTLTLLHEVVDELEVVC-------ELVYQYA-KSNGMKGFDIAIVVSFGYFIPKSVLSSKYGGINMHPSLLPRHRGPAPIHHTLLSGDKETGISIITLDPKKFDVGDILLQTR-QNKLTTNGAAMVIKTLEQTKAPKVNRQIEWSQHDCATIWNMYRAF-SIGVSKIYEDGKKNDVQEFLFG Pucgr2 -----RVLSCGSDSFSPTILNRLIHL--EMFSLIRGGLKKV--------EDRPLKHWDELVPI-FPYRIPREMIEDRSSLTTMVPGC-----GADPM--SVSRQGARAGVSMQEVSPLGFETSKILAQKP-INALANLVADMLHQLIPN-----------------------YLPL-K--------------------- Punst1 K-PF-DILFFGRDEFSCTVFEELHRVWSSVKIATGRRGSQLSPLKTLA-ASRDFRTWHLLVTASFGRILSRAHLSAPGRRLNVHPSLLPAYRGPAPIQRALLDGARTAGACAIEMTER-IDAGDVWGHRR-VDLLAREGGALLVSVLRDPRAPAITAAVDFRTMSASDIVRIHDAI-SLGVSALKPQDRALVSADWWNG Rhior3 ---------------------------------------MLT--KGVA-ELKTLKQWDLAVVVSFGYFIPPHIISRRLGAINVHPSLLPNYRGAAPIQHAILNGDRKTGVTVQELDEREFDAGRILNQKE-V------------------------------------------VM-G--------------------- Rhoto1 KPPY-NVLFFGADFFSCAVLKELWELIGKTVVVVGRKGA--PPLKTLA-QQAELKEWNVIVTASYGHMLPLEVLNKQLNALNVHPSILPRWRGAAPIQYAIMKGDEQLGVTVQELSRGA-DKGRILAQK---SHLAREGGLLLVDVLRNTLAPKITKEIKWNLQSAREIERLNRAI-GVAIDQIKKDS----GIDWYNG Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 VQPL-NVLFFGSDTFSNFSLQALNEIVDNIQVVTGRQKSILPPIFDMA-EKTKQEMLNAIIAVSFGKLIPGDLIRAP-LALNVHPSLLPRHKGSAPIQRALLEGDTYTGVTIQTLHPDRFDHGAIVAQTEPLDQLGALGAQLLGQTLRESYAHRITTEIHWARDSAAELLNKLETL--LCVSRLQFEGFAVERAQFMAR Salro QQWL-RVLFFGTDSFALPTLRTLVEIIDHVQVACDD-----HVVRDFC-E----NDWDVGVVASFGHIIPDVMLDHRLGALNVHPSLLPKYRGAAPLHHTILNGDSTAGVSIIEVSKRTVDVGRVLLQES-F-----LGAQMMLRVLGDSYAGKRFKKVDWGSMTRAAVVNMHRCY-AVPITHVQFPTRRPITIQLYHQ Schco3 TEPF-KILYMGRDEFSCSVFKHLHDVWQELHIATGRRGSQLSPLKTLG-QSPEFKTWHMLLTASFGRIIPQRMLAAPHNRLNVHPSPLPAYRGPAPIQHMLMAGERETAVCVIEMLRK-VDAGAVWGREE-LDLLGDVGGRLLVRVLREPRAPLIQAALDFARMSAEDIVRLQRAI-GLGAREAKMQDKAQVGADWWNG Schpo1 KIPL-NVIFLGTDEFSIPILRKLIGCVQRVRVVSSRR----IPLPPAAMEAKLQDGWQLAITASFGRFVPFKILNQPYGGINIHPSLLPKYRGAGPVYSTILNGDRLAGVTIQTMDSKQFDKGKSLAQAY-LKILSLGAAGMLEHVLLQSWAKKITPEVNFESMNTQQIYNMSRAF-NVIKGGIRLSARKIVDPTFNSG Sorma SDPL-RILFCGSDVFSCYSLKALHALIKSIDVMVGRGYKEIVPIQNLA-EEDTFTGWNLIVAVSFGLFVPPRILGQKYGGLNVHPSLLPD----------------------------------------------------------E---------VD------------------LRVGKIKVEG---------KG Sphar ------------------------------------------------------------------------------------------------------SGDSEAGVSLIELSKESFDSGNVIAQVQ-CNRMVPLSADMLLSTIASTLAPKVDNTIDWSTYTCAAIDRIQRAL-AVGFRTVQSATKKLTSSAFANG Spipu1 NRPY-NILFFGSDEFSIASLRKLREIISHIEVVTNKK----VPLKEFA-VKKTLKDWDLAVVVSFGYFLPRRVIGAPSGAFNIHPSLLPRYRGAAPIQYTILNDDKETGVSIIELDPQRFDVGGILKQTR-IDALAEVGAKDMLETIRETHAPKIPKAVDW-QLPRERIYRLHRAI-GLACSKLKVEGKRALGIDFVNG Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 TRPF-NVLFFGRDEFSCTVLKQLHHIWQSLTLVTGRRRSQLSPLKSLG-DEPDFRTWHVLITASFGRILRKSLLNTPHRRLNVHPSLLPAYRGAAPIQHALLNGEKETGVSVISMLEM-IDTGDIWGSRK-MDSLAVEGGDLLVSVLRDPIAPLIAPSISFTAQTAQSILRHYRAI-SVKVKQLKTQDRNLLGAAWWNG Tapde11 RADI----------------------ISDLRIITGRGLSVLAPLTILA-RK------DLIIAVSFGHKIGPEVLQASHGGLNVHPSILPRYRGPAPLHHALLNNDHETGVSIQTIHPTKFDQGEVLMQSP--GKTAMIGATMLRDLL--SQAPKIDKSVDWSTWPVAKLVRWSSVF-D-----LQVRRQRA-------- Thetr -RGL-SVVFFGTDDFSLPVLNALVE-VASIEVVV-------CTIESVA-R-TTLKYWDVGVVASFGYLIRPHIASARLGIINVHPSDLPRHRGPAPLHHTILAGDTTTAVCLIDVDPTAFDVGALLARSP-L-----TGGKLVRSALRSSHAPKVSKDVPWATAPAAHVLRLHR---------LQVEGKAPCSADFANA Treme1 DKRF-DILFCGSDSFSVSSLQALLGIWKSIHVLVGRGGKSRSELGVYA-EREGIRAFSLLLTVSFGHILPSPLLSLPYHRLNLHPSLLPKFRGAAPIQHTILTGVQTTGVTLQRLVERGIDAGDILG----IPRLAIKGADLLVETLRKTRAPKIRKEVKWEKQGAKEVERLYRGI-GIEIRSVKPPNKPERQVEWWNG Trire2 SDPL-RILFCGSDAFSCESLRALHRLVESLDVMVGRGFKEIVPCKSVA-EHETFRGWNLIVVVSFGLFVPPRILKSKYGGLNVHPSLLPHLRGPAPIHHAMMRGEKYTGVSLQTLDPKAFDHGTVLAQTP-SEDLAKVGAEMLVQGLRDIHAPKVGKGINWLEWKPSDFERFVNIF-GVRVRSVKVDG---------KT Umbra1 KQGY-RVLFFGNDEFAESHLKALLEVISHIELVTGRKLSVLT--KVFA-EKRTLNGWDLGVVVSFGYFVTPNVLKTPLGAVNVHPSLLPAYRGASPLQYTIMNRDKVGGITVQELDEKAFDAGRILAQEE-IDRLSSIGVRLLVETIRDTKAPKIKKEVDFEGMEAVDIEAIFRAI-GIGIKRLKAENKAERSADFCNG Ustma22 ----------------------------------------MSPVKQLA-LQAGLDNYAILLTCSFGHLIPDRLLDSPWQRINIHPSLLPNLRGAAPIQWALARRLHTSGVSIQTLEKGRFDTGTIVNQQA-FRVMAHRAADLLVLTLSNTYAPKLKSKIQWSTWAAPDIVARERAF-ALAVAQLKVAGKRRKTAEWWRA Walse1 QRPF-NILFLGSDSFSVDVFKAIYQLYNNLSVITGRRLKELPPLLALS-NE-QLRSFDVILTASYGHLLPSSLLNLPKQAINVHPSLLPKLRGAAPIQWSIARQLHETGVSIQTMQDDVFDSGDILYQKS-YKDLGQIAAECATNVLENTHAPKVHRKVDFNKMPASVVDSRYRAF-GLQVKSLKPPGKRIMSAEWWNG Zygro1 ---L-NVLYFGSDEFSIHSLRALNEV-DKLQLVTGRSKSIKVPIVNVA-DQSREDMLNMIIAVSFGRLIPAQLLEQP-YSLNVHPSLLPRYKGASPIQYTLLNQDRYTGVTIQTLHPHKFDHGSIVAQTIPLDQLGLQGGSLLKHVINDCYASKITSELHWPQDTAETAITKLETL--LKIKELQFEGFKMEKPQFMKS [Cluster2354.fasta_al_trimmed; alignment length = 110] Allma1 TNVSWEDQQNINKFSKLNSRLEEEYGEKKKRLELLEDVTSELELC-DED--ELVYQVGDAFVNAPYSQVQE-WLENEATADVEKLKDEMDKMDELKAILYKRFGNSINLE Ashgo11 VQVLYEDQQRINEFSKLVMRLEAELRSQRQEKEYVDDAALEIELV-DED--AALYKIGDVFVLMRQEEVAA-QLEAAADARIRQLEEEEERMRALKQVLYAKFGDSINLE Aspfu1 NEVRREDQEKINRFSRLHQRLEEQLKAKQKDKEDLEEISTELELA-DED--ELVYKIGDAFFQLPLADAQS-LLAEQIDLEVSRLEETLGELQQLKVTLYARFGRSINLE Aurde31 TEVTWEDQQRINRFSTLNSKLDATLAQLKA--QALDDLTTELELA-DED--DTVFKIGETFVHLVVTQAQE-RIEERLDSEILALAERTEEMKELKVALYAKFGKQINLD Batde5 VEVTWEDQRNINMFSKLNTRVEEAYEDKKREKEYLDDLTNELELA-DED--EPVYKIGDAYISLSLTDAQS-RIETVLDQELKTLGANVGEMIKLKALLYAKFGKSINLD Botbo1 TEVTWEDQQKINTFSKLNSRIEEQYKEKKADKEALDDLAMELELA-DED--ELVYRVGDVFVHMTLERAQA-RLEEKIDGELSKLREVVEQMKELKVILYGRFGKAINLD Botci1 VEVRREDQDKINRFSRLHQRLEDELKSKHKEKEDLDDVSGELELA-DED--DMIYKIGDSFISLPLPEVQE-LLTENIEEEVILVEEKLSEMTQLKVELYARFGRSINLE Caeel TKVSAEDQALLNKFARSYQTLKADVKEAKTLIDNINEASDEILLLDDEDS-ASICRIGSCFVHFNGDSLNE-HLETTAEKVLSEKTSELDDMEQIKKVLYAKFGDQINLD Canalb1 TEVTYEDQLKINKFSTLISKQTQQLSTLKTEKEYLDDLSIELELI-DDD--EKIYKVGDCFVFLPKDQVLE-KIEDSLEEKINSIEELIDELKDLKAQLYDKFGDNINLE Cangl IEVTFADQQKINEFSKLIMRLEAELKKERQEKEYLEDVSLEIELI-DED--EEVYKMGEVFVFLKQSKVVE-QLEEIIDEKISQLESKQDRIKELKTSLYAKFGDNINLE Capow -QLTWEDQERINLFGRLNNRLDELIKINKKRLDGFSDAEESILLA-DSDE-APVYRLGEVFVEMPADKATE-MLTEKVTAEVNKQQEEVAKMVELKRALYAKLGDTINLE Catan2 VNVSWADQSKINTFSRLNGRLEAKYAQKKKEKEDLDDLASELELC-DDD--EIIYRVGDVYVNAPYERVQE-WIQSALDMQVAKLKDDMDEMDSLKAVLYKRFGNAINLE Cioin VQVTLEDQKKINLFAKKNGNIETELEEIKKALQNIEDAGDDLLLLEDEDS-EAIYQLGEVFIQHNLEETQG-LLEDKYEQRMKQLKEEAGMMKELKVQLYAKFGDNINLE CocheC53 -------------------------------------------------------------------------------------------------------------- Coere1 AEVTWEDQQHINQFSKLNGRLDEEYKQQKEEAEYLSDLVMEIELL-DED--EPVYKIGEAFIEFTLEKAQA-RVEERIDQRVADLNSQMSEMDELKKKLYGKFGKAINLE Conco1 ---------------------------------------MEIELL-DDD--ELVYQLNDIFIELKVEAARE-RSEEASKTKLDELSDKTDKMDALKKVLYGKFGQSINLE Conpu1 VEVTWEDQQRINQFSKVNNRIEEKVEELKQEKEALDDLSTELELT-DED--QIVYKIGEAFLHLRQPKALK-RLEDSLNKEFEKLSSSAEEMKELKVVLYAKFGRSINLD Copci AEVTWEDQQRINTFSKLNARIEQKLEVFKQEKEALDDLSPELELA-DED--EPVYKIGDTFIHMRQSRALK-RLEAKIDEQVQALSTQADKMKELKVLLYAKFGKAINLD Croqu1 VEVTRTDQDKINKFSNLNLCLEVILKTKKDEIDYLSELETELMMI-DED--ELVYKLDTSFIHLNPIKAIE-LTEQKLIKMVEGLQEDLDEMKELKKVLYSKFGKSINLE CryneH991 VEVAWEDQQRINTFSKLNNRIQDLLKARNEEKEYYDDLSTELELA-DEDDPQPVYKIGEAFFYLPLRDARR-QLKKKYEMEIEGLESKAEGMKELKVLLWVMLLLAMNGK Crypa2 VEVRREDQDKINKFSRLHQRYEEALKLKNKEKEELDDITMELELA-DED--DTIYKIGDSFFHVTVAQAQE-MLGAKIEEDISEIEDKLNEMSQLKVELYARFGRSINLE Debha1 TEVSWDDQQKINKFSTLINKNLEVLKKLKEEKEYLDDLSLEIELL-DED--EKIYKVGEVFIFMKVNKVIE-KIEEVLTEKISNIESSVDLLESYKKQLYARFGNNINLE Dekbr2 AEVSWEDQQKINEFSTHISKLTAELEKLQTEKEYIDDLSMEIELI-DED--DNVYKIGDTFVLIKQSEAME-RLEGYLETKITELETQIEKLGALKKQLYAKFGTAINLE Dicdi TEVCAADQKMINLFGRLNNRLMREKKAKQEDLEKATDSQDDLFIA-DDD--SKFYSMGEAFLEVNKEDAES-LIENKLEEDIKKIDSDINKHKELKVILYAKFKNSINLE Dmel VHISFEDQQRINRFAKHNARFKAELETKRNELKSLEEALEEIELF-DED--EDIFLVGEVFLSHKLEKTQD-MLKEQVLKEIAGVEAKAKEMDELKAHLYQRFGSNISLE Enthi -------------------------------------------------------------------------------------------------------------- Falba IHITLDDQKNLSKFNQLHTQVREELREKRDLARDLEEASNEMLLA-DED--KPIYAFGSGFAALPLETATQ-LIEELATKRVDELADKNTTLSTLRSEIYARLGQSVNLD Fomme1 VEVTWEDQQRICTFSKLNTRHEARIEALKEEKEVLDDLASELELA-DED--QPVYRIGESFVHLPLPRALK-RLESGLSDEMSKLSEQTEEMKELKLVLYAKFGSAINLD Fusgr1 VEVRREDQDKINRFSRLHQRLGDELSAKNKEKEELDDLSTELELA-DED--EKIYKIGDAFFHVSVEQAQE-MLEETLEEESTSLEDKLSEMTKLKVDLYARFGKQINLE Galma1 AEVTWEDQQRINTFSKLNNRIEEKLTELKDEKEALDDLSTELELA-DED--EPVYKIGEAFVHMSHPRALK-RLESSVDTRVGVLAAQADQMKELKVMLYSKFGKAINLD Ganpr1 IEVSREDQNNINTFSKLNARIEEQLEEKKKEKEYLDDLTTELELA-DED--EPVFRLADAFLNLSIPHARR-RLESGLDKEIADLERDAGQMTELKAVLYGRFGKSINLE Gloin1 -------------------------------------------------------------------------------------------------------------- Hisca1 TEVRREDQEKINRFSRLHQRLEEQLKTKHKDKEDLEEVSMELELA-DED--EKIYKIGDSFISLPLSEAQS-LLTERIDDEVSKLEENLSELQQLKVALYARFGRSINLE Klula1 VTVAYEDQQRINEFSKLIMRIEQDLTQQRTEKEYLDDVSLEIELI-DED--EKVYKIGDVFVFLKQKEVVE-KLEENIDSNIEKLESDEARIKELKSILYAKFGDNINLE Lacbi2 AEVTWEDQQRINTFSKINTRIQEKLEELKQEKEALDDLATELELS-DED--QPVYKVGEAFLHMPHPQAVK-RLENVIDARVAALAAQADEMKDLKVTLYAKFGKAINLD Lenti61 TEVTWEDQQRINTFSKLNTRIKEKIEVLKVEKEALDDISMELELA-DEE--EPVYKIGDAFIHMPYSRATK-RLESSLNDELGKCNSSAETMKELKVALYAKFGRAINLD Malgl1 -------------------------------------------------------------------------------------------------------------- Mellp23 VEVNQTDQANINRFSNLNVQLEAKLQAKKDELDYLSELETDLMML-DDD--ELVYKLETSLVHMTPAKATE-LNEKKLSDTVDRLQADLEEMSQLKKLLYKKFGNTINLE Mnele IHIKYEDQEKINQFARYNSKIKDDLTAKGKQLQNLTDAAQDVELELSEDS----FQL----------------------------------------------------- Monbr VPILKEDQDRINEFARLHAKLTDNYKASQDRAEGYNDASEELML--QDD--ESIIAVGDCFFMLETDQANE-LLEEAAEAEMEGLREKVGRLVELKGVLKAKFGNSIQLD Morel2 IQVSWQDQENINTFSKYNAKLEEAYESKKTEKEYLDDLAMELELA-DED--EPVYRIGEAFVSLSLEAAQE-RISEELDQEIEGLKTQMDKMDGLKKVLYARFGNAINLE Mucci2 -------------------------------------------------------------------------------------------------------------- Mydma VEITQEDQKMINDFANKNSKIKALILSNKKQLQNYEDAGDEIML---NDD-ESVVYIGETFFKMSKDEAQA-FIDESIEKEIKILAEKAEELKDLKIKLYAKFGTNINLE Neucr2 IEVRREDQDKINRFSRLHQRLEEELKNKNKEKEELDDLETELELVEDED--ELVYKIGDSFFHIPLEQAKE-MLGAKLIKEIEALDDKLEEMTGLKVELYARFGKTINLE Orpsp11 VEVNWEDQQNINLFSTLNIKYEAEYEKVKKEKEYMDDLQQEIELSEDEN--EKVFLIGDAFVEITIPECQE-LIEASFEKQLDDYQSKIDQMARLKAILYGKF------- Pench1 NEVRREDQEKINRFSRLHQRLEEQLKGKQKDKEDLEEVSMELELA-DED--ELVYKIGDSFFQLPLSDAQG-MLSEKIDADVSKLEDSLGEMQQLKVALYARFGRSINLE Phybl2 VEVSWADQQKINEFSKLNAKLEEQYEKMKQEKEYLDDVAMELELA-DED--EPVYKVGDTFAHVPVSEALE-RVEEKIQLELDNIRSDVEKMEELKKLLYAKFGNAINLE Picst3 TEVLWEDQQKINKFSTLIGKQLAVLEKLKTEKEYLDDLALEIELL-DED--EKIYKVGEVFIYMKVSKAVE-KVEEKLTDKISETSNLIDSLDDLKKQLYAKFGNNINLE Plicr1 AEVTWEDQQRINSFSKLNTRIEEKLEELKQEKEALDDLSTELELA-DED--ETVYKVGEAFLHLTHSRALK-RLEQGLAEQVSKLSDSAEKMKELKVTLYAKFGRAINLD Polpo TSVTHEDQKMINTFGRLNNRLLKQKKYLEEDLEKARDAQDDIFLAEDED--IKYYLMGEAYMETPKEETEE-LLENSLESDIEKINAELEAHKELKVLLYGRFKSSINLE Pucgr2 IEVNFKDQKMINQFSNLNLKLKKLIKSKSVELDDLIELENELLLKTTEDN-DLIYKLDSSYIHIKRSTFQETKLPDRSREMISKLNSDLTQMSELKKTLYSKFGNTINLE Punst1 AEVTWEDQQRINEFSKLNTRIEGKLAELKQEKEALDDLSTELELA-DED--EPVYRIGETFVHVPLNRALK-RLEGSIDSQLSELADKAEGMKELKVILYAKFGKAINLD Rhior3 VEVSWVDQERINEFSKYNAKLEEEYERLKKEKEYLEDVGMELELA-DED--EPVYKIGDAFVHMNVTEATE-RIEEKLGLQIEE-------------------------- Rhoto1 VPVTKVDQDRINQFSRLNSRLDGLRKQKED----LEEIETEMELV-DED--EVVYKLDTTFVHIPASEALE-HLQERIKREVEELEEEKTTMDELKKELYAKFGNSINLE Rozal11 LRILQSDQNSINRYSVINSQLKAQRKALKQRLVDLEDAISELELM-DGQ-----LKVGDAFILDDAEKIVE-RLNEQIEAELEEKNHDFEEMAKLKKILYAKFGNQIQLE Sacce1 TQVTFEDQQKINEFSKLIMRIAQELSLQREEKEYLDDVSLEIELI-DED--EPVYKVGDLFIFMKQSKVTA-QLEERLDNKIETLEDKQRRLDALKAILYAKFGDNINLE Salro -------------------------------------------------------------------------------------------------------------- Schco3 EEVTWEDQQRINSFSKLNTRLNEKLKELKVEKEALEDLSTELELA-DED--EPVYKVGETFLHLPLPRAQK-RLAADVEKRLAAAADSVDQMKELKVVLYAKFGKAINLD Schpo1 VPVLAEDQRNLNEFSVLHSRQELDIKNLKTQIEDIVDAKNECELL-DEDDGDDILKVGDAFFQVSLPVLLD-QLEESLEKQVDVLRSSMERIQELKSMLYSKFHDQINLD Sorma IEVRREDQDKINRFSRLHQRIEEELKNKNKEKEELDDLDTELELVEDEE--ELVYKIGDSFFHIPHEQAKE-MLGAKLEKEIEDLEDKLEEMNGLKVDLYARFGRTINLE Sphar VEVTWEDQRMINTFSRLTSNLEKDLEVKTRQKKNLEDAESDLMMIMDDE--ELVFRIGDVYIEVSQSDATE-RLEMQLNEDTEAVEEKMTELTKLKTQLYGKFGNNINLE Spipu1 AEVTWEDQQNINAFSRLNMKLEEAYEEKKKEKEYLDDLSSELELA-DED--ELIYRIGDAFVSLPLSTCQE-RIESNLSDELGQVSSRIGKMNQLKVILYKKFGNSINLE Sporo1 ATVTLSDQNAINKFSRYNSRLELLNKVKED----FEEVETELELL-DDD--EQIYKLDSTFLHLPVSEALE-HLQKSTTDKVEALEREKHEMEGLKKVLYEKFGNSINLE Stehi1 IDVTWEDQQRINTFSKLNARIEERRDELKQEKEALDDLSMELELA-DED--QPVYKVGETFLHMPHSRATK-RLLSVLDKELSGLEEKKEGMKELKVSLYAKFGKAINLD Tapde11 -------------------------------------------------------------------------------------------------------------- Thetr VDVNWEDQQRINKFGRLNQRLEADIGRWQEELDNLEDASTEVLMA-DDD--DALFQIGEVFVMLPADEVEA-RIEEETEAKVTAAEAEIEALAELKVVLYGKFKNSINLE Treme1 IEVAWEDQQRINTFSKLNNRINEQLKKKQDEKEYYDDLSTELELA-DDD--QPVYKLGEAFFCLSLSEAKK-QLRKRYDKEIGDLEKRASGMKELKILLYAKFGRQINLE Trire2 VEVRREDQDKINRFSRLHQRLKEELQLKSKEKEELDDISTELELA-DED--EKIYKIGDAFFHLSLEQAQE-MLGTRIDEETTALEEKLEEMTQLKVELYGRFGKQINLE Umbra1 VEVSWEDQQKINSFSRLNTRLEEQYEKLKQEKEYLDDLSMELELA-DED--EPVYKIGDAFVHMPLDKALE-RITEKVQADIDDLKSQMDQMEELKKALYSKFGKSINLE Ustma22 IEVTWEDQQSINAFSRLNSSILHTLSLVREQRESLDDLSLELELA-DED--ECVYKIADTFVSLPHPIAMD-RLESQADTEISKMQEQIDEMKALKVKLYAKFGDNINLE Walse1 EEVTWEDQSRINAFSKYNKRIEELLTDRKTEREQLDDLSMELELA-DED--APVYKLGDAFVSISLEKAQE-QIEESLDSAIEELKSAADNMSELKVHLKSKFKDSINLD Zygro1 TNVTFEDQQKINQFSKLIMRIEQELNIQRQEKEYSDDVSLELELI-DED--EPVYKVGVIFLHLKQKEAVE-QLEESTQGRIDELESEQDQLKELKSILYAKFGDNINLE [Cluster2361.fasta_al_trimmed; alignment length = 79] Allma1 EYHQRSEAALDTLVDALEALGDDVTYSSGVLTLSLGTYVLNKQPPNQQIWLSSPSGPRRFDWWVDARSDLLRAELEQLV Ashgo11 AYHKQADEFLNDLLDRLEALGDDSEYSQGVLTLSVGTYVINKQPPNKQIWLSSPSGPNRYDLWVSLRDAVLSRELGRAL Aspfu1 QYHEFAEHYLNVIQNEVEKAQEEAEYSAGVMNISVGTYVLNKQPPNKQIWLSSPSGPKRYDWWIYLRDDLLNAELSLNI Aurde31 DYHSLADDTMDTLLDQLEVLVDEVEYSSGVLTLNLGVYVINKQPPNKQIWLSSPSGPKRYDYWFYSRDDLLSQELSKAL Batde5 DYHKFANVYLNSLLEYLEELGDDVVYSSGVLTLKLGIFVINKQPPNKQVWLSSPSGPKRYDYWIYARDEVINEELSNML Botbo1 EYHKLADETMHSLLDSLEEIYEDIEYESGVLTFKMGTYVINKQPPNKQIWLSSPSGPKRFDYWFYSRDGLLEEELSTVI Botci1 QYNDLSDKYMDMMVEKLEELQEDVEYSAGVLTLSFGTYVINKQPPNKQIWLSSPSGPKRYDFWIYLRDELLLNEVGVDL Caeel EYETAADSTLERLSDYFDQIADDVSHAMGVLTVNVGTYVINKQSPNKQIWLSSPSGPKRYDLWTYAHDSLLNREFRKIL Canalb1 EYAKVSNEYLENLSDSLEELNEDSELSQGVLTLTLGTYVINKQPPNKQIWLSSPSGPKRYDLWVTLRDSLLEEEISTAI Cangl QYHQHSESFLEGLFDNLEELSEEVEYSHGVMSLTVGTYVINKQPPNKQIWLSSPSGPNRFDLWISLRNSVLDKELHDAL Capow EYHRLADSTLHDVRASLEETIDDIIEQSGVMTMAFGTYVLNKQAPNQQMWLSSPSGPHRFDWWISTQNELLETEFASRI Catan2 DYHRHADATLERLLEALETLGDDVTYTSGVLNVKLGTYVLNKQPPNKQVWMSSPSGPRRFDWWVDSRQEVLVKELDELL Cioin ------------------------------------------------------------------------------- CocheC53 EFHERADHYLGELQQRLEEAQEEVDYSSGVLEVT-NTFVLNKQPPNKQIWLSSPSGPKRFDWWVYLRDEILRKELGVDV Coere1 EYGKVAEDTLNRLLVFLEDISDDVEYTQGVLTLSVGTYVINKQPPNKQIWLSSPSGPERYDFWFCRHTALLTRELSKAL Conco1 DYYQSSEKTMNNLFEQLEELLEDLEYQSGVLTLKLGTYVINKQPPNQQIWLSSPSGPKRYNFWFYHRDNLLETELKEVF Conpu1 TYHELSDTTMNIMLENLEELLDEIEYESGVLTLGLGTYVINKQPPNKQIWLSSPSGPKRYDYWRYSRDELLNEELSRVF Copci QYHALSDSTMDSLLENLEDLLDEVEYHSGVLTLNLGTYVINKQPPNKQIWLSSPSGPKRYDYWIYLRDDLLNTELSQAL Croqu1 EYHQISDETLHHLTESLETLIEDVDYSSGVLTFSMGTYVLNKQPPNKQIWFSSPSGPKRFDYWFYSRDDLIRDEVSNAL CryneH991 EYEHVSERDMETLNESLEIFCEEIEYSSGVLNLTLGTYVLNKQPPNLQIWMSSPSGPSRFEYWVHHRKELLSGELKEIL Crypa2 DYHDLADEYLEAIQDRLEEVAEDIEYSAGVLNVTFGTYVINKQPPNKQIWLSSPSGPKRYDYWVYLRDDLFVQELDIDL Debha1 QYNNISNEYLETLADELEMLSEDCELTQGVMTLSVGTYVINKQPPNKQIWLSSPSGPKRYDLWITLRDTLLEEEISVAL Dekbr2 QYRHLADETLDTIATDLEDLFEDVDNSAGIVTITTGTYVINKQPPNKQIWSSSPSGPNRFDYWTSLRKDILEKEVSDMF Dicdi LFHDIVDEEFELFVDRLEILSEEVEGNDGVLTIIVGTYVINKQTPNRQIWWSSPSGPKRFDYWVDNRDQLLNSEINTLC Dmel TYERVCSDTLDALCDYFEELTEDVAYSDGVLTVNLGTYVINRQTPNKQIWLSSPSGPKRYDFWIYKHSELLQQEIPGIL Enthi ------------------------------------------------------------------------------- Falba GYNNASETTLENLADQLDGLAEDADYSSGVLTLDIGTFVINKQPPNQQIWLSSPSGPRRYNLWVPCPTSLLSRELTDML Fomme1 RYHELSDVTMDTLLESLETLLDEVEYSSGVLTLNLGTYVINKQPPNKQIWLSSPSGPKRYDYWYYSRDELLDEELSKAF Fusgr1 EYHEIADEYLDNVVNRFEELQDDVEFSAGVLTIDWGTYVINKQPPNKQIWLASPSGPKRYDWWIYSRDQVFLEELGVDI Galma1 EYHALSDKAMDDILATLEEVVEEVDYHSGVLTLHLGTYVINKQPPNKQIWLSSPSGPKRYDYWVYSRDGLLSEELSTIF Ganpr1 TYHRIADNTLDSIVESLEILGDDVNYSMGVLTLALGTYVLNKQPPNKQIWSSSPSGPKRFDYWVYHRDEMLNEELRELI Gloin1 TYHRLSEIALEYLLEYFENLDDDVEYSSGVLTLKCGVYVLNKQPPNKQIWLSSPSGPKRYDFWFYHRDGLLNEELSTVF Hisca1 QYREYVEDYFNVLLTKVEQMQEEAEYSVCIYTKTY-IYVI-------RCILGSN--------SIYHSYLLLFSPWTVPI Klula1 VYHEISDEFMDSLLDQLEILCDDVEMSQGVMSIEVGTYVINKQPPNKQIWLASPSGPNRFDYWVSLRDDILNKELSDRL Lacbi2 KYHLLSDATMDTLLESLENLLDEVEYHSGVLTLSLGTYVINKQPPNKQIWLSSPSGPKRYDYWVYSRDNLMNTELSNAL Lenti61 QYHQYADATMDKMLESLETLLDEVEYGSGVLTLKLGTYVINKQPPNKQIWLSSPSGPKRYDYWVYSRDDLLNQELSDVL Malgl1 ------------------------------------------------------------------------------- Mellp23 EYHQISDETLHQLTESLEALIEDLDFSSGVLTFSMGTYVINKQPPSKQIWFSSPSGPKRFDYWFYARDDLIRDEISNAL Mnele ------------------------------------------------------------------------------- Monbr ------------MSAEFEEIFDDVALANGVLTVDMGTYVINKQTPNQEIWFSSPSGPKRFKYWRSPTEELLRREISELL Morel2 DYHTASDASMDRMVEYFEDLGDDVEYQSGVMTLKLGTYVVNKQPPNKQLWLSSPSGPKRYDFWFYGRDYLLDTEITKAI Mucci2 RYHRLSDEVLDHMVTRLEELADDVEYNQGVMTISVGTYVINKQPPNHQIWLSSPSGPQRYDFWFYHRDEVLNTELSKAI Mydma DYNTVVEKTLEDLHDHFDILADDSTLTDGVLTIKLRIYVINKQTPNRQLWLSSPSGPKRYDFWVYSHDEFLSKELQTLF Neucr2 EYHKLADQYMDRLVTHLEELQDDVEYSAGVLTVSFGTYVINKQPPNKQIWLSSPSGPKRYDYWVYLRDQLFRDELQIDL Orpsp11 EYHELADEFFDNLTECIESILEDTEFSSGVLTIKLGTYVINKQTANRQIWYSSP------------------------- Pench1 EYYEYSEHYFNVLQSELEKAQEEAEYSAGVLNISVGTYVLNKQPPNKQIWLSSPSGPKRYDWWIYLRDELLNSELTLRL Phybl2 DYHKAADKTFDLMVERLEAIGDDVEYSQGVMTLKLGTYVLNKQPPNRQIWFSSPSGPKRFDYWFYSRDELFNEELSDAL Picst3 EYNSISEEYLESLADSLEDLSEDCELSHGVMTLTIGTYVINKQPPNKQIWLSSPSGPKRYDLWITLRDELITEEVSSAL Plicr1 RYHELSDATMDTLLESLEDLLDEVEYSSGVLTLILGTYVINKQPPNKQIWLSSPSGPKRYDYWLYSRDDLLDQELSDAL Polpo -YHTIVDDELELFSDRIEVLIQDVETSDGVLTINLGTYVINKQTPNRQIWWSSPSGPKRFNYWIDNIDNLLQSEIKTLC Pucgr2 EFHQISDQTLDELTEALERLVEDVDYSSGVMNFSMGTYVINKQPPNKQIWLSSPSGPKRFDYWFYSREALLSSEIDSIL Punst1 QYHNLADATMDKMLDSLEGLLDEVEYSSGVLTLILGTYVINKQPPNKQIWLSSPSGPKRYDYWIYARDALLDEELSAAV Rhior3 RYHRLADEILDHMVEKLEEISDDVEYS------------------SRQISDCT-------------------------- Rhoto1 EYHDVSNAAMDHLTEYLEEKLDDVEYSSGVLTVKLGTYVINKQPPNKQIWLSSPSGPKRYDYWFYHRDDLLNRELRELL Rozal11 ----------------MEEIIDDIEYTNGVLTMKLMIFVLNKQPPNRQIWLSSPSGPRRFDFWFYTRDELLSKELSEIL Sacce1 KYHEEADDYLDHLLDSLEELSEDVELSHGVMTLEIGTYVINKQPPNKQIWLASPSGPNRFDLWVSLRNDILTEEVEKAI Salro EYHKLADAWLDAMHDTFEDLIDDVSLSNGVLTLALGTYVINKQTPNKQIWFSSPT------------------------ Schco3 RYHAISDATMDTMLDNLENLLDEVEYSSGVLTLILGTYVINKQPPNKQIWLSSPSGPKRYDYWYYARDDLLNEELSKAL Schpo1 EYHRVADDTLDVLNDTFEDLLEDIQYANGVITLMLGTYVINKQPPAHQIWLSSPSGPKHYEYWCSTRDGILSSEFSKWF Sorma QYHKLADEYMDRLVTHLEELQDDVEYSAGVLTVSFGTYVINKQPPNKQIWLSSPSGPKRYDYWVYLRDQLFRDELQIDL Sphar QFQRLADDTMTQLTDIFDEIVEDVTYGNGVLTVDLGTYVINKQTPNKQIWLSSPCGPKRYDFWSYSHDEVLSKELSDWA Spipu1 LYHRIADDTMDNLVEVLEELGEDVVFASGVLTLSLGTYVINKQPPNKQIWLSSPSGPKRFDWWQCLRTDMLSRELSSLL Sporo1 DYAKISESTMDSLTEYLESHLEDIEYSSGVLTVNLGTYVINKQPPNKQIWF----GPKRYDFWFYARDGLLNQELRTLL Stehi1 QYNELSDATMDAMLDSLEALVDEIEYNSGVLTLKLGTYVINKQPPNKQIWLSSPSGPKRYDYWIYSRDTLLDKELSDVF Tapde11 ------------------------------------------------------------------------------- Thetr TYHAVADETLEMVQEAIETVCDDSALSQGVLNVAFAVFVLNKQTPNQQIWLSSPSGPMRFNYWRHWRTNLLRQEFSQLA Treme1 EYDHIADEDLDTLHEALELLCEEVEYSAGVMTLTLGTWVINKQPPNQQIWMSSPSGPARFGRWVHFRTGLLESELRQIL Trire2 EYNDLANEYLNDLLEKFETLQDDVEYSSGVMTVTVGTYVINKQPPNKQIWLSSPSGPKRYDFWIYTRDELIHKEIELEL Umbra1 MASKVADHTLEGILDVLETIGDDVEYSQGVLTLKLGTYVLNKQPPNKQIWLSSPSGPKRYDYWFYARDEVLNNELSDIL Ustma22 QYHKLSNNVLDSLQETFETLLEDIECASGVMNLRCGTWVINKQPPNKQIWLSSPSGPKRFDFWFCLKEQLLQDELSLVF Walse1 TFHKLSDKVFDSLTEALESELEEVDYSSGVLTLSLGTYVINKQPPTRQIWVSSPSGPRRYEYWLDVRDQMLDEELSPIF Zygro1 TYHEQADTFLESLSDQLEALSQDVELTQGVMQLELGSYVINKQPPNKQIWLASPSGPNRFDFWISLRDDILNEEINQAV [Cluster2365.fasta_al_trimmed; alignment length = 138] Allma1 ETLLYVAGYYARAKVENDAIKRRLVTHAIVCLLPVVLILLLFLRNYAVSPIAEEFVFRACIIFPIILLSPLFFGIAHLHNIYDALKRAILSTVFQLMYTTVFGWIASFFYVRT-GNIIGPALIHMFCNVMGFPYVVGL Ashgo11 AATSYVAALYVRN--DPKAIWYGMKAVGCGVLAALSILGSLYARNYVFGPITEELVYTSMVLQNLLLATPMFFGVAHVHHARQP-AQVALTSSFQILYTTLFGTFTNYIYYHTAGNLWACILLHAVCNYLSFPLLCGL Aspfu1 LTLLYVAPFYIRD--APSVIRARIRAVSWSCSLAWLLTAILFTRNYVAGPVTEEIMFRSAIVPLIVFVAPLYFGIAHVHHFYESIFAALFRSVFQFGYTTIFGWYATFLYLRT-GSLLAVIVAHSFCNWCGLPLVSGA Aurde31 IGSSYVASLYLRN--DPSVIRARLTAVSLSTLSAHLLTPLLYARNIIMGPITEELTFRSCVVAVIIFAAPLSFGVAHAHHAWDALKRAVLTCVIQLAYTTIFGAFCTFLLLRT-GSVLPAIGSHMFCNLYGLP---G- Batde5 LSTLFVGSFYLRN--DPDVIRQRFKAVALTCAISLGICGALFLRNWVVGPIVEEIVFRGYMVPITIWCLPLFFGIAHLHHAWESIIHAATSSIFQLMYTMVFGWLATYLFIRT-GSLYGPIATHIFCNIVGFPYISGI Botbo1 FTFAYISCLYFRN--HPSVIKARLRAAVISTCLPHLIAPLLYTRNFIVAPITEEIVFRSCIVSVIVFLTPLWFGAAHIHHAYEALKRAIIMSGAQLTYTTLFGWYTTYLFLRT-RSIYPPITAHIFCNVMGIPHILGI Botci1 YTLIYVIPFYLRD--APTVIRGRIRSVTLSCIVCVGLTAILFARNIVAGPVTEEVLFRSASVPLIIFLTPVVFGLAHVHHFYEPMVGAVLRSLLQFSYTTLFGGYATFLYLRT-GSLLAVICVHAFCNWMGFPLVVGA Caeel LPISYVLLVHLRN--DPESVKRRFKGALLSNFVPFILMNAFYLRDIIVGPITEEIVFRACSSTLTILLNPIPFAASHFHHIWDSLAHSILQRGFQFCYTYLFGAFATWLQLTT-RHAIVPIIAHAFCNAQGLPYSVGF Canalb1 TACSYVFAIYFRN--DPDVVRHRISRIIILCALTIYFILILYSRDYLLAPVSEELIYRGLIFLIQHVFTPFLFGVAHIHHGIQPTMTIVITTGFQFTYTSMFGKLSEVIYSATDQNLWSCIVLHMICNIFGLPIVLGI Cangl ISLSYVAVLYIRD--DPRVIKRRLKNVLMVSILNLCLVMLLYIRNYIFAPITEELFYTSLLLNTLLWQPSLFFSIAHIHHAYESTTSIIINTLFQMAYTGIFGAFTNFVFLRTGGNLWSCILLHSFCNVMGFPLFMGI Capow LTGVYVGSLYIRD--DPKVVPTRFASATLACVAPLALTATLFARNIVVGPVTEEITFRACMLPMALLVAPVMFGSAHLHSIIQAAWSGI---LLQLAYTTVFGVYASALFLRT-GHIIAPILSHSLCNYIGFPYVFGL Catan2 LSVLYILGYYL----EEAVIRSRLITIVATCFVPTLLIVTLFLRSYFLGPICEEYIFRACIILPIVAWTPLFFGSAHLHNIFDALKRGVVASLFQFTYTTLFGWIVAWVYVRT-GHVISVMLMHMFCNVMGVPYVVGL Cioin FATMYVGSLYVRD--HPQTIKERFLRVTVVSILPSLLIIILFLRNFFVAPLSEELVFRGCMMPL-ILLAPWFFGLAHFHHAYEHTLSAIVISIFQASYTTVFGILSSFIFLRT-GHLTSAFMSHALCNIMGFPFVLGL CocheC53 YVFIYVIPFYLRD--APSSIRARVRAVTFSTLLTMLLVVILFARNFVVGPVSEELVWRSLIVPLMVFLTPLYFGIAHVHHLYEPLALAIARSLFQFTYTSLFGFFAAFVFVRT-GNVYSCVLAHAFCNWMGLPLVAGA Coere1 ---MYVASIYVRD--NPHIMRRRMFGVSVSTLVSLVLMAVLFLRNYVVGPVTEELVFRSSVIPLCVFVSPVIFGVAHVHRAISALLKILVSTTVQLTYTTVFGWIVAALFLRT-RSIAGPIVAHVFCNIQGLPFIVGL Conco1 NSLLFVLTFYLRD--NPKVIKFRLICTLLVGLTPLYLTVIVYLRNYIWGPFIEELVFRSCNMLLKVSLTALYFGLAHVHHGFEPINKILIITAFQFSFTSLFGSYCSFSLLKT-KSVYGPILSHIFCNVMGLPQLISL Conpu1 FASAYVGAIYLRD--DPAVIRARLRAVSIA---PHLLAPLWFLRNYVVAPLTEEIVFRSCILGVMVGVGPIFFGVAHLHHAYEALRRAIFISLFQLAYTSLFGTFTGALLLRT-HSLSPAFTAHAFCNVMGVPYIVGI Copci FGICYVGSLYVRD--DPDVMRARVTAVSIASILPHVVVPVLFLRTYILGPITEEIVFRSCVLTAMVFLTPLTFGV----------------------------------------------------------YLLGM Croqu1 LAVSYVAILYIRQ--HPAVIRARVLAVILITFLALLLTATLFLRNLVIGPISEEIVYRGCIIATIIFLSPLWFGAAHVHSIREALVNGCLIAAFQFVYTTLFGWYASFIHLRT-GSVIAASLCHSFCNMMGVPYISGM CryneH991 FTTSYVGSLYIRD--HPITIKRRMEAVASSTLLPYLLTPGLMIRNYIVGPLTEEVVFRSTILAVLVFGTPMWFGIAHAHHGFEAALQAILTTLFQLTYTTLFGWFASYLYLRT-GSVFPPLSAHIYCNLMGIYYLAGI Crypa2 YTLLYVIPFYLRD--APSVIRARITAVSLTCALALLLTALLFARNYVMGPLTEELLFRSAAVPLTIFLSPLVFGLAHVHHLYEPFSAAVLRSAFQLGYTTLFGAYATFVYLRT-GSLLAVFAVHVLCNCMGLPLVAGA Debha1 VAISYVATIHVRN--NPDVIHHRIVRITTLCSISIKLILILYMRDHIFAPITEELIYRS-VLLTKILLTPLFFGVAHVHHGYDDFSTAALTVVVQVMYTTVFGVLSNYLFLETGNNLWCPIVVHCICNLMGFPLIVGI Dekbr2 ATLGYVAVLHLRD--DHIVVRSRIHRALISTLATIILFAGLFIRDYLVAPGTEEITYTGIAAGIVIIWTPFLFGTAHLHHAFE--KSAIIFTTFQLLYTTLFGVLTNLVFFNS-ESIWCCIAAHSFCNFMGVPLAFGV Dicdi --------------------------------------MVLFLRDIIVGPLVEELVFRSVICPIIIILSPFLFGFAHAHHIFQYFIN--LIKLFQVCFTSLFGMYSAFLFFRT-GNILACFIVHSFCNIMGLPFIIGL Dmel LAVLYVGSLYIRD--HPTTVKRRFASVSMVMLAPYSLTVLLFLRNHVIAPLSEEFVFRACMMPLAVFITPLFFGVAHLHHIAEELSTALLIGLFQFIYTTLFGFYSAFLFART-GHVMAPILVHAFCNHMGLPYLAGF Enthi LTVILLAFLGINDE-NKIAIIRMIIGIGYCVFVHLTQIVILFIRALVVAPIIEETLFRGVFIPYTFIYCSMLFGLAHINHLITIDKAAIINTMIQVGFTTLFGMYSSYVFFST-KSVISCILCHAVANYLGFPYIIGI Falba IGVSFVASFFFRD--DPTVIMARIKAVSASIVIPIPLFMCFFLRNWIFAPFAEELAFRSCIFPLIHLLVSLYFGVAHLNHLRDPTVAALVVVLVQLVYTSIFGTLAAYIYYRT-GHILAAIMSHVVCNVMGFPFALGI Fomme1 ISSSYVLSVYIRN--DPAVIKARSLLASASTALAYFIVPALFLRNYLMAPITEEVTYRACVLSVMIWVAPCWFGLAHIHHGFEALRTALMSTIFQFIYTTVFGWLCSFLFLRT-GSIIVPTIAHIFCNVMGFP----- Fusgr1 YCLIYVIPLYFRD--APEAIRARIFAVSLSTALVLWLTALLFARNMVAGPITEECLFRSAGVPLTIFMSPLIFGLAHLHHFYEPLPVAIARSLLQLSYTSLFGAYATFLFLRT-GSLLAVVLVHTFCNCMGLPLVGGL Galma1 LAVIYVGSLYLRD--DPDVIRARLVAVSVATLVPHLVTPILFIRNYCVAPLTEEIVFRGCVLAIMIFLAPLTFGMAHIHHAWDALKRAIITSCFQLGYTTLFGFHVSYLFLRT-GSIFPPITAHIVCNIMGIPYLIGI Ganpr1 LASAFVGTLYLRN--HPRVILARFKSVALVCVLSLLLSGTLYLRDYIVGPAAEEFVFRACMVPLTIFCVPLVFGVAHAHHMWEALKQSVLVSTFQFCYTTMFGWYSTFLFIRT-GSVLAPVASHMFCNVMGLPFFAGL Gloin1 FTLCFVGGLYFKD--HPKVIMNRGISVIISCSIPLGLTMSLFARNLIFAPFTEEYVFRCCMVPLIIFLSPLVFGIAHVHHAWEAAKVAIVISGFQLTYTTLFGWYATFLFVRT-GHIIPPFFAHMFCNMMGFPLFGGV Hisca1 FTLLYVIPFYFRD--SPSVIKARVRAVTTSCFLSFLLTALLFMRNFVAGPITEEVIFRSIIIPLIVLFAPLYFGIAHMHHFYESFTASIARTVFQFGYTTIFGWYATFLYLRT-GSLPAVILVHAFCNYCGLPLVVGA Klula1 ISLSYVVAVHTRD--DPKVIKARMKAVIALSAFHLSLAIVLYSRDYIFGPITEELFYTSMMLVALTLIVPNLFGIAHVHHAFENLANIIFITLLQMSYTWLFGSFTNYLFLNSSGNLWSCILIHTFCNYMGLPLVISI Lacbi2 FSLTYVGSLYIRD--DPDVIRARLFAVCLATTLPHLITPTLFLRNYVVAPITEEIVFRACILSIMIFLAPLAFGLAHVHHAWDAAKRALFTSLFQLTYTSLFGFHTSFLFLRT-GSILPPISAHIFCNVMGVPYVAGV Lenti61 FTFSYVGSLYLRN--DPDVIRARLLAASASTLLPCLVAPILYLRNYIVGPITEEIVFRACMLSVMIFLSPLWFGIAHLHHAWDALRIAVMQTLFQLAYTSLFGFHCAFLFLRT-GSLLPPTFSHIFCNVMGFPYLLGI Malgl1 LTSQF-----------------------FNPSVSLMLTSCLYIRNYIIGPCTEELVFRSCMLTSLMLTPPLYFGIAHIHHAWEAGRLAFQSSALQFTYTSVFGWYADFLFMRT-GTVWAPLTAHILCNVMGLPHLTGF Mellp23 IAVSYVAILYLRQ--HPAVIRARLFAVTFVTFFPLVLTAILFLRNLIIGPITEEIVFRGCIIATITFLSPLWFGAAHVHSIREALLRGSMISLFQFAYTTVFGWYASFIYLRT-GSVVAASLCHSFCNFMGFPYLLGI Mnele ------------------------------------------------------------------------------------------------------------------------------------------ Monbr -------------------------------------------RNYVVAPVTEEIVYRAMVLALLVLGSPLFFGLAHVHHLW-PWPAVLG----QFGFTTLFGWLNAWTFLRL-ESCYAAIAAHSFCNYMGLP----- Morel2 FTMLFVGSLYVRN--HPLVIKQRFKGIALTCFVPLLLVGCLFMRNFVVGPISEEFIFRACMVAIMIFVLPLVFGIAHINHAYEALINAAAMAAFQLLYTTLFGWFATFLFLRT-SNLIGPCLCHTFCNMMGFPFVLGM Mucci2 FTLIYVAGFYIRN--DPPVILARMKAVTVASLIPLLLTCMLFLRNYIVAPLTEEFVFRACMIAVLIFVSPLYFGIAHLHHAWDALQQALFSSLFQFAYTTLFGWYASYLFIRM-GSLWPPVLCHSFCNMMGFPFPLGI Mydma LSICYVGSLYIRD--HPTTIKQRIKSVLIVCLLTLFLTVILFTRVAVVAPFTEEFIFRACLIPLIIVLAPLFFGVAHLHHILEPVLEAFLVSLFQMVYTTMFGIYSAYLYIKT-GQLIGIVACHSFCNLMGFPYIIGL Neucr2 YALSYFLPFYLRD--NPSVIRARIRSVCISCFCALGLTALLFARNIVAGPLTKKLLFRTSSVPLIIFYSPVIFGLAHVHHFYEPVFAALLRSVFQFSFTTLFGAYATFVFIRT-GSLLAAFAVHAFCNGMGLPLVGGA Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------ Pench1 LTLLYVLPFYLRD--APSVIRARIRAVTASCIVSLFLTAILFLRNFVAGPFTEEVMFRSAMVPLIVFLAPLYFGIAHVHHFYEPALAALLRSLFQFGYTTIFGWYATFVYLRT-GSLLAVVVIHSFCNWCGLPLVAGA Phybl2 FALIYIAGFYLRD--HPKTIASRIKSVILASIVPLLLTMILFLRNYIAAPFTEEFVFRACEIALLIFISPIWFGTAHLHHVWEALKRALLSSSFQFAYTTVFGWYASFVFVRT-GSVWPPFLCHSFCNMMGFPYIVGV Picst3 ------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 FATGYVGSIYLRD--DPSVIKARLLAVSIATAAPHFLAPLLFLRNYVVAPLTEELLFRSCVLAVLIGFSPVWFGFAHIHHAYDALQRAIIGSLFQFAYTTLFGAYAAFLLLRT-RSVWPAVSAHIWCNLWGLPYVAGI Polpo -------MILI------------LTAIGISTLL------VLFVRNYVIGPIVEEVVYRSSICPIILF-SPLLFGLSHLHHIYPNINRIVTS-----------------------------------CKLI-------- Pucgr2 AACSYVGVLYLRL--HPVILKARLWAVSVSCFFPVILTAILYLRALILGPLYEEIVFRGCILAFLIFSTPLWFGFAHVHGVWEALMIATIQSTFQFIYTTIFGWYAAFVFLRT-GSVISATLCHSFCNYMGLPYLGGM Punst1 VTASYVGILYARD--DPAIIRARLVAVSFSTFTAYLVTPMLFARNFVFGPITEELVFRSCILAAMIFVTPLWFGLAHVHHALEALKTALVSSLFQFGYTTLFGFHAGYLFLRT-SSIWPPIVAHVFCNIMGLPYILGV Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 VSSSYVGSIYLRN--HPAVIKARLLAVTLASLSPLGLTASLFLRNYIVAPLTEELTFRSCILAIMIFLSPLWFGLAHVHHAREALLVAIAQSLFQLAYTTLFGWYASFLFLRT-GSIIPPFLAHAFCNAMGVPYTLGI Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ISISYVLPLYARD--NPRTIKSRMQKLTIMLISCVAMLLTLYCRNFIFAPITEEIFYTSMLLTTLFWQPSLFFGLAHAHHAYETTVSILLTTCFQILYTTLFGGLTKFVFVRTGGNLWCCIILHALCNIMGFPLVLGL Salro LAALYLVSLYARN--HPRAVIARCIGASAATIAGLVLFALLFARNVVVAPITEEIVFRGCITALCNLLCPLIFGIAHFHHVLR-----VPVSSVQLVYTSVFGSLSSLLMLRT-HSLAAAVAAHMFCNHMGLPYVFGL Schco3 FALSYVGSLYVRD--DPEVIRTRLRAVTFSSIFPYLLIPILYTRNYVVAPITEEIVFRACIVAVIVWGSPLWFGMAHLHHAWEALQQALAQTAFQFTYTTLFGAYCVDIFLIS-GNILAPVSAHIAANFMGMPYYLGI Schpo1 FTAIYVVSLYTRN--DPKVITARCISVLLASSVSLLHAATIFIRNIIIGPLSEELTFRCCIVPIIIFVAPLLFGMAHIHHTYEAYIAAALQTVVQFSYTTVFGWYTTHLFLST-HSLFPSFLVHAFCNSMGLPLLLGV Sorma YALSYFLPFYFRD--NPSVIRARIRSVCISCFFALGLTALLFARNIVAGPLTEELLFRTSSVPLTIFYSPVIFGLAHVHHFYEPVFAALLRSIFQFSFTTLFGAYATFIFIRT-GSLLAVFAVHAFCNGMGLPLAGGA Sphar ----------------------------------------------------------------------MFFGIAHMHHVYEPWRTALLRAV-QFSYTSAFGLYSAYVFLKT-GHFAAPLFCHAFCNALGFPLVGGL Spipu1 LTLTFVGSFYVRD--DPRVVRRRFMAAAGTCAVPLLLTMTLFLRNYIVGPLTEEFVFRACMVPLTVFMLPLCFGIAHIHHGYEALKQALLSGVFQFFYTTLFGWFSTFLFLRT-GHVM---------------KPVGI Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 FTLAYVVPLYLRD--DPKVIRARMASVTLSTLAPCLITPALYLRNFLVGPLSEELAWRSCVICVLIFFTPLSFGAAHLHHAWEALKNAILSTVFQFTYTTLFGFHCAFLFVRS-GSVIPPLLAHIFCNVMGVPLFRSL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------ Thetr TTLAFVGSLYLRD--EPAIIKRRLVSIVVVSVAPLAASMACFARNVVIAPLGEEYVFRALLMTAASLISPLCFGLAHLH----AL-------LVMLCYTSIFGGYSGLLFAAT-RSFWPPVAVHAFCNYMGLPLFTGV Treme1 FASSYVGCIYLRD--HPDTIKRRMKAISITTLIPYVLTPILFVRNYVVGPMTEELVFRSCILSVLVFGTPLWFSLAHAHHAWEAAIQATMGCLFQIGYTTLFGWFASYSFIRT-GSILPPLASHIFCNIMSIYYLIGI Trire2 YTLVYVLPLYARD--APEAIRARITAVSLSTTASCLLTGLLFARNLVAGPVTEECLFRSAAIPLIILLSPVVFGLAHLHHFYEPLVAAIARSVLQFSYTSVFGAYANFLFLRT-GSLLAVVVVHAFCNSMGLPLVGGS Umbra1 FTIVYLAGFYVRN--EPKVIVARCKAVIISSILPVLLTASLFLRNFVIGPLTEEFVFRACVIALLVFASSLYFGLAHLHHAWEALKTALLQSGFQFLYTTVFGWYVSWIFIRT-DSILAPTLCHTFCNIMGFP----- Ustma22 FTFSYVASLYVRD--HPVVIRARIKTASLATALPLLLTAMLFLRNYLVGPLTEELVFRCTILTPLILLTPAFFAIAHAHHAYNAALTGLLTATLQLCYTGVFGWYANFLFLRS-ASVVAPFGAHVWCNLMGLPHAIGI Walse1 FSISYVYAVYFRD--DPAVMISRMKNVVVSNIAPIILAPILYFRNIIVAPITEEITFRACIISAIILLTPLFFGLAHVHHGRQAFIREMLVIAVQLTYTTLFGSFAAYVFLRT-NSIWPCILTHMQCNYFGLPYTAGI Zygro1 VSVSYVAGVYARD--DPRIIIQRMGRISLILIAALVLMGLLYVRNYVFAPVTEEIFYTSMILNCLVWFTPFFFGLAHIHHAYETLATVILTTLIQVTYTTLFGCLTNCVFLKTGGNLWACIVLHAFCNYMGFPLILGI [Cluster2367.fasta_al_trimmed; alignment length = 78] Allma1 MGRL-RVSTKNRTKDIDQIDLDLPGQGQHYCVECARYFINDTSMQEHLKSKVHRRRVKELRDG-PYTQKDA-EEAVGL Ashgo11 MGRY--YKTKRRTKDLDLIDETKPGLGQHYCIHCAKYFETPAALKTHLKGKVHKRRVKELRGV-PYTQEVA-NAAAGT Aspfu1 MGAVRKIKTKRRTRDYDQVAEDLPGLGKHYCVECSKWFESEYNLVAHTKGKNHKRRLRLLREE-PHSQKIA-EAAVGL Aurde31 MGRL-RARTRARQKDLDQIDYEKPGLAQHYCVECAKYYETDIALQSHWRSKVHKRRVKQLKEP-AYTIEES-ERAAGL Batde5 MTRV-GTRTRARTRDLDQIDTDLPGMGQNYCIECARHFINSSALLDHQTTKLHKKRVKVLATGKAYTQKEA-EEAVGL Botbo1 MGRL-RSRTRVRTKDLDIIDVERPGLAQHYCVECAKYFESDVALKSHWRGKVHKRRCKALKEP-AYTIEEA-ERAGGL Botci1 ------------------------------------------------------------------------------ Caeel MPS--G-KTRKRPKDLDQIDYDLPGNGQFYCIECERHFVDEKTRQLHRKTKLHKNRVKTLKEV-PYTQAEA-NAAGGS Canalb1 MGRY--YKTKRRTRDLDLIDELKPGLGQYYCIQCAKYFENQISLDRHTKSKIHKRRVKSLNER-PYTPLEA-EAAAGV Cangl MGRY--YKTKRRTKDLDLIDETKPGLGQHYCIHCAKYFETGIALKTHLKGKIHRRRVKELKSI-PYTQEVA-DAAAGV Capow --------------------MDLPGLGQFYCVACARYFIDELSLNVHFKSKVHRRRLKELKEP-AYTQEDA-EAAAGM Catan2 MGRL-RVSTKNRTKDLDQVDLDLPGQGQHYCIECARYFINEEARAEHVKSKVHRRRLKEIKEG-AFSQAEA-EAAVGL Cioin ------------------------------------------------------------------------------ CocheC53 RGQDSKKKTRRHTRDLDQIVEDLPGLGQHYCKECAKFFESDANLGAHQKGKVHKRRVKQLREE-PYSQKEA-EAAVGL Coere1 MVRM-RYKTKRRTKDLDQIDEDLPGLGQHYCIECARYYIDEAALACHRRGREHKRRLRDLKDP-AYTQEEA-EAAAGL Conco1 MGRL-AYRLRRRTKDLDQIDPDLPGLAQHYCIQCSKYFTDDKSLVEHRRGKYHKKRLRLLKDA-PYTIKEA-EMAAGL Conpu1 MGRL-RSRTRARTKDLDQIDLEKPGLAQHYCVECAKYYETDHALRSHWRSKVHKRRLKELKVP-AYTIEES-ERAAGL Copci MALL-ERKIWIKSSLLTWIDYEKPGLAQHYCVECAKYFETDNALQSHWRSKVHKRRLKQLKEP-AYTIEES-EMAAGL Croqu1 MGRL-RRKTKRYTRDLDQIDEDTIGLGNWPCVECARFFADQRSLDEHKRGKVHKRRVKALAEG-PYSLEEA-MRAAGL CryneH991 MGRL-RARTRARVKDLDQIDEDKPGLGQHYCVECSKYCETAVALQSHLKSKIHKRRLKELKEG-AYTVGES-ERAAGL Crypa2 MGVPNKTKTRRYKRDIDQIPEDLPGLGRHYCTECAKWFDTETTLVVHRRGKPHKRRVKQLKEE-PYTQKDA-EAAVGL Debha1 MGRY--YKTKRRTRDLDLIDENKAGLGQYYCIECAKYYENQEALDRHTKGKVHKRRARDLKQR-PYSNLES-EAATGV Dekbr2 MGRY--YKTKRRTRDLDLIDEDKAGLAQYYCIHCARYFQDNKALAHHYKSKVHKRRVKQLNVN-PYSTLEA-EAATGL Dicdi MGRYSGRSTKNRAKDIDQIDPDLPGMGQNYCIHCSKHFVTNEDLQSHIKGKPHKIRVKELKTK-PYSLAES-QIP--- Dmel MGMVSKWRVRNRRRDLDQIDLDKPGFAQFYCVHCAKYFIDDTAMQAHFRTKVHKRRLKALEIE-PYSIEEA-ERAAGR Enthi MPQ--RLSMKHKTKDFDQIDEDKPGFGQFYCGVCDKHFISQAVYLKHCTQGPHKSKVKRVQKEKPWTVEDA----KGR Falba MTRV-RIRTRRRPRDLDQIDEDLPGLGQFYCLECARYFEGPDHLSKHKLSKQHKQRVRELKDE-PYTHEEA-EAAAGM Fomme1 ------------------------------------------------------------------------------ Fusgr1 MGVTNKTKTRRKTRDVDQVAEDLPGLGRHYCVECSKWFDTGSTLVSHQKGKPHKRRVKQIAEG-PYTQEEA-EAAVGL Galma1 MGRL-RSRTRVRTRDLDQIDYEKPGLAQHYCVECAKYYETDAALQSHWRSKVHKRRCKQLREP-AYTIEES-ERAAGL Ganpr1 MTRV-ATKTKRRTKDLDQIDPELPGQGQFLCVECSKHFINDTALVAHRKTKLHKKRVKDLKVP-AYTQKEA-ESAVGL Gloin1 MGKVGRYRTRNYAKDLDQVNEDLPGLGQYYCIPCARYFINSEALNEHQRGKNHKKRVKLLKEV-PYTQAEA-EAAVG- Hisca1 MGATKRIKTKRRTRDYDQVSEDLPGLGRHYCVECAKWFESDYNLVAHRRGKNHKRRLRILKEE-PHSQKMA-EAAIGL Klula1 MGRY--YKTKRRTKDLDLIDETKPGLGQYYCIHCAKYFETAYALKTHLKTKIHKRRVKELKGV-PYTQQVA-DAAVGC Lacbi2 MGRL-RSRTRVRTKDLDQIDFDKPGLAQHYCVECAKYYETDTALHSHWRSKVHKRRLKQLKEP-AYTIEES-ERAAGL Lenti61 MGRL-RARTRARTRDLDQIDYEKPGLAQHYCVECAKYFETDHALRTHWRSKVHKRRCKQLKEP-AYTIEES-ERAAGL Malgl1 MGQIHRARTRARKLDYDQRDPEKAGLGMFYCVECDRHFPNMNDRNAHVASKQHKRIAKKVLTEKPYTHEEA-LRGAGI Mellp23 MGRL-RKKTKRYGRDLDQINEETIGLGEYPCQECARFFINLHSLQHHLKSKVHKRRLKDLADG-PYSLDEA-MRVAGL Mnele TGKY-AKRTRRRATDIDQIDVDKVGKGEHFCMPCDRYFMNSGDLDKHERSKPHKKRIKNLSEP-QYSHAEA-DKAGGL Monbr ------IKSKRKTKDVDQIDGDLPGLGQFYCVHCARYFVNQLSLAGHFKSKVHKRRVKQLSET-PYSQAEA-DAAAGL Morel2 MGRL-RYRTKRYMRDIDQIDPELPGQGQFYCIQCAKHYINKESLAEHQKGKIHKKRCKLLREE-PYSQAEA-DAAAGL Mucci2 MGRL-RQRTRAYTRDLDQIDTDLPGLGQHYCVECARHFISEAHLTEHLKSKLHKRRLKKLEDE-PYTQEEA-DRAAGI Mydma MGKPQRHRTRNRTKDVDQIDPDLPGDGQFYCVICARYFMDGKNLSEHKKTKNHKKRLRVIKEK-PYSVAES-QMAAGM Neucr2 MGIFAKCKTRRRLRDVDQVVEDLPGLGRHYCVECAKWFDMESTLVKHTKGKPHKRRLKELKEG-PYTHKEA-DAAVGL Orpsp11 VGKAQRARTRARTKDLDQIDPDLPGMGKNYCIPCARHFTSPEAYEAHIHTKLHKR----------------------- Pench1 MGALRRVKNKRRTRDYDQVVEDLPGLGKFYCTECSKWFESDYNLKAHTKGKNHKRRLRILREE-PHSQLLA-ERAIGL Phybl2 MGRL-RYRTRNYTRDLDQIDPDKPGLGQNYCIECARHFVTSDALTVHLKGKLHKRRVKKVQEE-PYTQAEA-NAAAGM Picst3 MGRY--YKTKRRTRDLDLIDETKPGLGQYYCVECAKYFENQLSLDRHNKGKVHKRRVRELKKK-PYTPLEA-EAAAGV Plicr1 MGRL-RMRTRARTKDLDQIDLEKPGLAQHYCVECAKYFETDTALNSHWRSKVHKRRCKALKEP-AYTIEEA-ERAAGL Polpo MGRYKGRKTARRGKDIDQVDPELPGLGQFYCVHCAKYFVAQSDLDTHLTGKKHKRRVKDLKVK-PYTVEDS-QLP--- Pucgr2 MGRL-RRKTKRYTRDLDQIDEDTTGCGQFPCVQCARFFVDSRSLTEHQRGKVHKRRVKELAAG-PYSLEEA-MRAAGI Punst1 MGRL-RGRTRARTKDLDQIDFDKPGLAQHYCVECAKYFETDNALQSHWKSKVHKRRCKQLKEP-AYTIEEA-ERAAGL Rhior3 -------------------DTDLPGLGQHYCVECARHFISDTHYQEHLKSKLHKRRLKKLEDE-PYTQEEA-DRAAGL Rhoto1 MGRN-RIKTRRYKRDIDQI-EDLPGLAQHVCVACARYFADSAALSTHIRGKPHKRQLKKLEEE-PYTIEES-RRAVGL Rozal11 ------------------------------------------------------------------------------ Sacce1 MGRY--YKTKRRTRDLDLIDETKPGLGQHYCIHCAKYMETAIALKTHLKGKVHKRRVKELRGV-PYTQEVS-DAAAGY Salro MGNPQRMRTRRKTRDVDQIDYDLPGMGQFYCVHCARHFVDEFTLEAHRRSKVHKRRLKQLSET-PYTQKEA-DAAGGL Schco3 MGRL-RARTRVRSKDLDQIDYEKPGLAQHYCVECAKYFETDAALHTHWRSKLHKRRCKRLAEP-AYTIEEA-EAAAGL Schpo1 MGRV-AFRTRVYGRDLDQIDPDLPGLGQHYCIECARYFDSSQALLVHKKGKVHKRRLKNLREE-PYTQEEA-EAAVNI Sorma MGVFAKCKTRRRLRDVDQVVEDLPGLGRHYCVECAKWFDMESTLVKHTKGKPHRRRLKELKEG-PYTHKEA-DAAVGL Sphar MGCVQRFRLRRRTKDLDQVDYDLPGAGQFYCLQCSKYYISDDALEKHSKSKVHKRRLKELKEG-AYTQEEA-ERAGGR Spipu1 MTRY-RKRTRARTKDLDQIDADLPGLGQHYCIQCSRYFTDAGALSDHYKTKLHKKRLKVLKES-PYTQKEA-EAAAGL Sporo1 ------QKTKRYRRDIDQI-EDLPGLGKFGCVSCSRYFADAVSLETHNRGKPHKRQLKKLEEE-PYTIEES-LRAAGV Stehi1 MGRL-RSRTRVRTKDLDQIDYELPGLGQHYCVECAKHYETDAALQSHWRSKVHKRRCKALKEP-AYTIEES-ERAAGL Tapde11 ------------------------------------------------------------------------------ Thetr -------------------DYDLPGKGQFYCVSCAKHFLDLGNLEQHRRGKPHKRQLKRLRKEKPYTQAEA-DAAGGM Treme1 ------SRTRARVKDLDQIDEDKPGLGQHYCVECSRYCETEIALKAHLKSKVHKRRLRELKQP-AYTVEES-QQAAGL Trire2 MGVGNKTKTRRKTRDVDQVPEDLPGLGKNYCVACARWFDTPFTLATHERGKPHKRRLKQLRDE-SKATSKS-EQSNVL Umbra1 MGRL-RFRTRAYTKDLDQIDADKTGLGQHYCVPCARYFPNDDTLQKHEKSKLHKRRVKKTQEE-PYTQKEVCVKSICR Ustma22 MTRTRHMRTRARKLDPDQIDVDKAGLGLFYCVECDRNFPSQKDQLTHIASKLHKRRAKKITEEPAYTIEES-LRAVGI Walse1 PGPS-RSRTRARTKDLDQVDETLPGLGQHYCIECARYFESDVALKGHTKTKVHRRRLKDLKEP-AYTQAEA-DAAVGL Zygro1 MGRY--YKTKRRTKDLDIIDETKPGLGQHYCIHCAKYMESAIALKTHLKSKVHRRRVKDLKSM-PYTQEVA-DAANGV [Cluster2380.fasta_al_trimmed; alignment length = 118] Allma1 MSQAVTALAYARVWHEVNVAQVLGRISPEIAKLLMGKHKPIFDPADCGDYVVVTNAARVRVTGTKQKLYRYHTGHPGGLRTEVIRHAVSGMLPKNRLRDDRLARLLVFPGPYKKNIAK Ashgo11 MSQKISGLAFARLWHHVDVARTLGRLASSIAITLMGKHKPVYHPSDCGDYVVVTNAQDLQVTGKKQKTYWSHSGRPGHLKSELLRKAVSGMLPKNRLRKVRLARLKVFDGPYKQNIVA Aspfu1 MSQTITRLAYSRTWHYIDVGRSLGRLASSIALFLMGKHKPIYDPSDCGDYVVAVGCSDLRTTGKKQKKYYTHTTRPGSLRGEVLRRAVRGMLPKNRLRDKRLARLKTFEGPYKENIVK Aurde31 MSQAVTALAYARVWHHVDASRVLGRLASRIAQVLMGKHKAIFDASDCGDYVVVTNARRVMVTGRKQLVYRKHTMYPGGLKDEIIRHAVSGMLPKNKLRQRRLDRLRIFPDPFKTNILR Batde5 MSL--NGLAHARLWHLVDAKKILGKLAQRISIALRGKYKPNYHPADMGDYVVVINAKDVALTGKKQKEYMWHSGYPGGQTTEPLKKAVWGMMPKGNLRKEQIHRLKLFAGPYASNIVK Botbo1 MSHVVTALAYARTWHSVNAERILGKLAQRIAIVLMGKHKPIFDRGDCGDYVTVTNAKLVRVTGRKQILYRSHSGYPGGLKEEIIRKAVSGMLPKNKLREKRLARLRVYEGPMQGNVMR Botci1 MSQTNTKLAYSRTWHHISASPPLGRLASRIALLLMGKHKPIWDPSDCGDYVVVTNCANLHTTGKKQKKYYRHNTRPGSLKAEVLRKAVSGMLPKNRLRDGRLGRLKAFEGPYKENLVR Caeel MSYRRQWLQFSRQWHVIDANQDAELLGDKVARYLAGKHKPIFHPEDCGDHVVVTNCKDIAMHAFDHTIYKFNMEYPKSKACRIAFLSVYRSLGNNLLRRRHIQRLHLFPDFVRKNIGS Canalb1 MSQRITASALTRVWHHVDVARSLGRLASSIAITLMGKHKPTYTPNDHGDYVVVTNCAHLKVTGNKEKTYWSHTTRPGTLRGEIIKRAVKGMIPKNKHRLVRMDRLKLFDGPYKDNLIA Cangl MSQKVTGLAFARLWHHVDLARTLGRVASSIAVTLIGKHKPVYHPSDCGDYVVVTNCQKVRITGKKQKTYWSHSTKPGNLKGELLKKAVSGMLPKNRLRKVRLARLKVFDGPYGDNFTA Capow LASTAAHLTHTERWFVVDAQQPAGRLANLLVQVLQGKHKPIYHHSLCGDHIVVINTKHVALSGTKEKVYRRHSGRPGGMKTEIIRRAVKNMLPRNNLRKRYLNRLHLYVDPHGANITG Catan2 MSQAITSLAYARVWHHLSASQVLGRLAPQIAHLLMGKHKPIYDPADCGDYVVVTSAANVRVTGAKQKLYRYHTGHHGGLKDQIIRNAVKGMLPKNRLRDDRLARLLVFPGPYQANIKR Cioin MSFGRQWSTFSKAWYLLNADQPPGKLADVAAKYLMGMHKPIYHPTRVGDHVVIINAKEIAYSGNKEKTFHSHTGRKKGRLTWIVKRYVYRRLPKGMYKRNLFQKLHVFADEIKENISF CocheC53 MSQVITRLAYARSWHHLDIGRALGRVASSIALTLMGKHKPIFDPSDCGDYVVATNCAQLHTTGKKQKLYRTHNTRPGSLKGEVLRKAVSGMLPKNRLRKERLARLKTFEGPYGENLIK Coere1 MSTGITALAYARVWHLVDARQILGRLGSQIALTLMGKHKPIYDPSDCGDYVVLVNARHIGISGRKQKLYRHHTQFPGGLKDKIIEKAVSGMLPKNRLRKVRLGRLFIFPEPYVDNIIK Conco1 ---------------------------------------------------------------------------------------------------------------------- Conpu1 MSQSITALAYARAWHHVDASRVLGKLAERIAIVLMGKHKPIYDKSDCGDYVVVTNVKDIQVTGRKEIVYRRHTRFPGGLKSDVLYHAVSGMLPKNRLKDRRLARLKVFGGIYKANIMK Copci MSQAVTTLAYARVWHHVDASRVLGKLAERIALVLMGKHKPIYDPSDCGDYVVVTNARSVKVTGKKQLLYRKHTMFPGGLKDEIIRHAVSGMLPKNKLRDRRLERLKIFPGIVGGNILK Croqu1 ------ALGFARVWRHVDAKQILGRLATQIATTLMGKYKPFFDPRDIGDYVVVTNARLIQVTGKKQKIYYSHSQYPGALKTMILKKAVSGMLPKNKLRDRRLDRLHIFPDPYQANLFK CryneH991 MSATKTALALTRVWHHTSAQRVLGTLASRIAWVLMGKHKPTYDPADAGDYVIVSDALQVRLTGKKDKVYYHHTGFMGGLKEEIIRKAVSGMLPKNTFRDRRLERLKIFPGTYKGNVLT Crypa2 MSQNVTRLAYSRVWHHVSASPPLGRLASRIATLLMGKHKPIWDPSDCGDYVVVTNCAALYTTGLKRKSYYRHNTRPGSLRGEILRKAVSGMLPKNRLRKKRLARLKAFEGPYEENLVR Debha1 MSQRISALALSRVWHHVDVARTLGRIASSIALTLQGKHKPTFSPNDHGDYVVVTNCAHLKVTGNKDRTYWSHSTRPGSLKAEVLRRAVKGMIPKNKLRLIRMDRLKLYDGPYKQNLIA Dekbr2 MSNKIAGLGFARVWHHIDLARTLGRLASQIAITLIGKQKPVGHPTDIGDYVVVSNCRYLKVTGHKDKTYWHHTTRPGTGKGEIIRRAVSRMLPKDSHRRRRLHRLKLYDGPYDQNIIA Dicdi MSRAINPLTSSHLWHVIDASHRVGRLATKISELLRGKHKPIYDRSECGDYVVVLNAHKVEFTGKKQKMYRKHSGYPGGLKEHIIRHAVMGMIPKNNSKFYLGKRLKIYDGPHQGQITA Dmel MSIAKQWATFARTWHIYDCTQNPFESAKLVKTHLLGLQKPIYHPMDCGDHVVLINTREIALPGDEKRVYFHHTGYPGGASTMVMKKAVYNSM--NLQRRHTMQRLHLFADEILQNVTN Enthi ---------------------------------------------------------------------------------------------------------------------- Falba ---MVNSATHLRVWHHIDATQRMGRVATQVAKVLMGKGKPTYHPADSGDYVVITNAARFELTGKKQRVHRYHTGYPGGLKDVVFRRAVSGMLPKNNLRPRMLRRLRIENGPFVANALR Fomme1 MSQAITALAYAKVWHHVDASRTLGKLADRIAIVLMGKHKPMYDPGDCGDYVVVTNARNIRVSGNKQKVYYSHTMYPGGLKEDIIREAVSGMLPKNKLRDRRLERLRIFADAFKNNILK Fusgr1 MSQVLTKLAYSRVWHGVSASPSLGRLASRIAVLLMGKHKPIFDPSDCGDYVVVTNCAALHTTGRKQKPYYRHTTRPGSLKSEVLRKAVSGMLPKNRLRDKRLARLKAFEGPYKQNLIR Galma1 MSQVVTALAYARVWHHVDASRILGKLAERIALVLMGKHKPIYDPSDCGDYVIITNSRKVKVTGRKQLLFRKHSMFPGGLKDEIIRRAVSGMLPKNKLRERRLERLKIFPAIVGANIMR Ganpr1 -----MSTPTFRVWLKVDASKILGRLATSVAVSLMGKNKPGYVPADSGDFVVVTNAKSVALSGDRKKTYWKYTGYPGGRYEEVIRLAVKRMLPKNNLRDVRLNRLKVFPGTVEANILK Gloin1 MSQAITALAYARVWHLVDARRILGRMATRIATTLMGKHKPIYDPADCGDYVVVINAKEVIVTGKKQKLYRHHTGYPGGLKDEIIRKAVSGMLPKNKLRENRLSRLYVFPDPYEQNITK Hisca1 MSQTVTRLAYSRTWHYIDVSRSLGRLASSIAVFLMGKHKPIWDPSDCGDYVVAVGCHDLHTTGKKKKLYYTHNTRPGSLKGEVLRKAVSGMLPKNRLRDKRLARLKVFEGPYKKNILK Klula1 MSQKVTGLAFARMWHHVDISRTLGRVASQVALALMGKHKPVYHPSDCGDYVVVTNCQALRVTGNKQKTYWSHTSRPGSLKSEVLKKAVSGMLPKNKLRKIRLARLKIFDGPYKSNITA Lacbi2 MSQVVTALAYARVWHHVDASRILGKLAERIALVLMGKHKPIYDPSDCGDYVIVTNSRAVRVTGKKQLLFRKHSMFPGGLKDHVIRHAVSGMLPKNKLRERRLDRLKIFPSILGMNIMR Lenti61 MSQAITALAYARVWHHVDASRVLGKLAERIAIVLMGKHKPIYDPGDCGDYVVVTNARNIKVTGKKQLVYRHHTMFPGGLKDEIIRQAVSGMLPKNKLRERRLERLRIFADVFQHNILK Malgl1 LLTPLTSLAFSRLWHHVDARRVLGGLARSIAVTLMGKHKPVYDQSDVGDYVVVTNAEHITVTGQKKKLYRHHTMYPGGLKEQILRRAVSGMLPKNKLRERRLERLKIFPNPYEANIVK Mellp23 ---------------------------------------------------------------------------------------------------------------------- Mnele MTHRFQLLTTSRQWVMVDATQPLEGLARTVCKLLEGRHKPIYSNIDVGDHVVVINTRKMVIPEKK--VLWWYSGYAQGHRTECLRLQVEFKLPQKLALKERLARLHLFPGPYAANISK Monbr MASQSALLTHTKRWVLVDAAQPVGRLAAQLSMQLQGKTKPIYHPTTMGDNIVVINADKVQFSGKKDKLYRWHTGWPGGFRTEVLRKAVNGMLPKNKLRRRMMDQLFLIEGPYGMNVDE Morel2 MSQAITALAYARVWHLVDAKRVLGRMSVGIAETLMGKHKPIYDPADCGDYVVVINAKAVKTTGTKDKLYRSHSGYPGGLKDAIIRKAVSGMLPKNRLREPRLGRLFVFEGPYEQNIIK Mucci2 MSQAITALAYARVWHVVDAKRVMGRLATNIATTLMGKHKPIYDPADCGDYVVVLNAKDILVSGKKQKLYRHHTMHPGGLKTEPLRKAVSGMLPKNKLRQVRMDRLKIFEGPYEANIIK Mydma MSFIVSFLTNARVWYLIDARQMNGKLAGYIAQILLGKHKPIYHPCDLGDHVVVTNCKHIYMKGHRSKIYRHHTGYPGGLKCQILWRAVRGMMPKTRSRNLQMKRLHLFEDPFATNIYA Neucr2 MSQTVTRLAYSRVWHHISAVPSLGRLASRIATILMGKHKPIWDPSDCGDYVVVTNCAGLYTTGHKRKTYYRHNTRPGSLQAEVLRKAVSGMLPKNRLRDKRLARLKAFEGPYKENLVR Orpsp11 ---------------------------------------------------------------------------------------------------------------------- Pench1 MSQVVTRLAYSRTWHYVDAGRSLGRLASSIALVLMGKNKPIYDPSDCGDYVVVVGCHDLKTTGKKQKKYYTHTTRPGSLKGEVLRRAVRGMLPKNRLKDIRLARLKTFEGPYKENIVK Phybl2 -----TALAYARVWHVVDARRVLGRMATNIATTLMGKHKPIYDPADCGDYVVVLNAKDVMVTGKKQKLYRHHTGHPGGLKTESIRKAVSGMLPKNRLREVRMERLLIFEGPYESNIIK Picst3 MSQRISAAALTRVWHHVDAARTLGRLAASIAITLQGKHKPTYSPNDHGDYVVVTNCKHLKVTGNKDRHYWSHTTRPGSLNGEILRRAVKGMIPKDKARLVRMDRLKVYDGPYVDNLIA Plicr1 MSQAITALAYARVWHQVDASRILGKLAERIALVLMGKHKPIYDPSDCGDYVLVTNSRNVKVTGKKQLVYRSHSMFPGGLKDEIIRHAVSGMLPKNKLRERRLARLKIFPGIRGQNIIK Polpo GSRAINPLTSAPLWHVVDATHHVGKLASKIAGLLRGKHKPIFDNSLCGDYVVVLNAHRIEFTGKKQKLYRKHSGYPGGLKEHIIRHAVMGMLPKNNNRYYLGQKLKIYDGPHNGQISQ Pucgr2 MYSPATGAGFVRLWRQVDAKQVLGRLATLIAHNLMGKHKPIFDPRDVGDYVVVTNARHVQVTGKKQKTYYSHSQYPGALKTMILRKAVSGMLPKNKLRDRRLERLHIFPDPYHGNLYK Punst1 MSQAITALAYARVWHHADATRVLGKFAIRIAHVLMGKHKPIYDPGDCGDYVVVTNAKKIKVSGLKQKVYRHHTMHPGGLKDEIIRRAVAGMLPKNKLRDRRLERLRIFSDPFKANIIK Rhior3 MSQAVTALAYARVWHVVDAKRVLGRLATNVATTLMGKHKPIYDPADCGDYVVVINAKDVLVSGKKQKLYRHHTMYPGGLKTEPIRKAISGMLPKNRLRQVRLDRLKIFEGPYEANIIK Rhoto1 PNSVVTALAYARAWRAVDADQVLGRLATRIAIVLMGKHKPIFDPADCGDYVVVTNCDKIRVTGKKQKVYRHHTMFPGGLKEQIIRKAVSGMLPKNRLREPRLERLKIFTGPYDANIIR Rozal11 NSSVIATLAYNRVWHLIDAKQILGKLATQIAVCLMGKTKPIFHRGDTGDYVVVINSNSFRLTGNKYKTYVRHSGYPGGFKAFVIKHAVKGMLPRNDLRSYRLDRLFCFEGPYADRIVR Sacce1 MSQKISGLAFARLWHHVDVARTLGRLASAIAITLIGRHKPVYHPSDCGDYVVVTNCQKIRVTGKKQKTYWSHSGRPGQLKGEILKKAVSGMLPKNKLRKQRLDRLKVFDGPYKQNITA Salro MATKFSLLTHTQRWYLVDARQKVGRLANMVSAVLRGKTKPTFHPGLSPDHVVVINAKDVVFTGRKQKLYRKHTGWPGGFRTEVVRKAVDGMLPKNNLRKQFMRHLHIFEDPYDRNIYA Schco3 MSQAITALAYARVWHHVDASRVLGKLAERIALVLMGKHKPIYDPGDCGDYVIVTNARNVVVTGNKQLVYRSHSMYPGALKDHVIRHAVSGMLPKNRLRDRRLERLYVFPRVLGSNILR Schpo1 MSTLNTALAYAKVWHHVSAK-PLGRLASQIATTLMGKHKPIYHPADCGDVVVVTDCSEIGISGRKNHKYYSHSGQPGHLKKDLLRRAVGGMLPRNKLWDRRMKRLYIYDGPYKANIFR Sorma MSQTFTRLAYSRVWHHISAVPSLGRLASRIATILMGKHKPIWDPSDCGDYVVVTNCAGLYTTGHKRKTYYRHNTRPGSLQAEVLRKAVSGMLPKNRLRDKRLARLKAFEGPYKENLVR Sphar IALRYNILTFTPKWWLVDASVPVGRLATQLTAVLQGKNKPIYHPSDVGDYVVVINAEKIALSGKKQKVYRHHTGYPGGLKTEIIRKATYGMLPKNDLRLQRIRKLHVFPTPFADNVGQ Spipu1 MSL--TGLAYGRVWHLVDAKKVLGKLSQRISIALRGKYKPIFHPSDCGDYVVVVNARHLALTGKKQKKYFWHSGWPGGVTTGPLKKAVYGMLPKNNLRKVQMGRLFIFADPYEKNIFR Sporo1 -----TALAFARTWRGVDATQVLGRMATRIAIVLMGKHKPIYDQSDCGDYVVVKNATKVRVTGKKQLVYRHHTMFPGGLKEEIIRRAVSGMLPKNRLRQKRLDRLMIFPQAYEANLLK Stehi1 MSQAVTALAYARVWHHVDASRILGKLAERIAIVLMGKHKPIYDPSDCGDYVLVTNCKKIKVTGKKQLVFRSHTMFPGGLKDEIIRHAVSGMLPKNKLRDRRLERLRIFEDVLQKNILK Tapde11 ---------------------------------------------------------------------------------------------------------------------- Thetr MALRVLAARAPKRWHVVDASESLGRMAVKVARLLSGKDKPTYHASTPGDYVLVLNARHLALSDKKSKEYVWHTQYAGGLKDDVVRKAVLGMLPKTKDRKRFNRSLFVFPDPFADDIEA Treme1 MSAVRTALALTRTWHHVSARRVLGTMASRIAWVLMGKHKPTYDPSDAGDYVIVSDALSVRLTGKKEKIYRHHSGFMGGLKEEIIRRAVSGMLPKNTFRKTRLERLKVFSEVYMNNIMK Trire2 MSQTITRLAYSRVWHQISASPSLGRLASRIAVLLMGKHKPTFDPSDCGDYVVVTNCAALHTTGNKRKKYYRHNTRPGSLRSEVLRKAVSGMLPKNRLRDKRLARLKAFEGPYKQNLIR Umbra1 ---------------------------------------------------------------------------------------------------------------------- Ustma22 MSQFVSSLAFARTWHAVSAKRVLGPLAVNIAKLLMGKHKPIYDQSDVGDYVVVTDAKQVVVTGRKQRVYRHHTMYPGGLKEEIIRKAVSGMLPKNTLRDRRLERLKIFDGPYEQNVLT Walse1 GSHTITSLAFSRAWHSVDAKRVLGRLAGRIALTLMGKHKPIYDPADCGDYVVVKNATKVLTTGDKQIVYRNHTTYPGGLKDEIIRKAVSGMLPKNSTRKHLLDRLLIFNDSINGNITK Zygro1 MSQKLTGLAFARLWHHVDIARTLGRLASSIAVTLIGKHKPVYHQSDCGDYVVITNCQALRITGKKQKHYWSHSGKPGHLKGETLKKAVSGMLPKNKLRKGRLERLKVFEGPYGNNISA [Cluster2383.fasta_al_trimmed; alignment length = 115] Allma1 FGLLIEMGKMEMLGYNVGQRL--VERLKDHA--RFDTLDVVKFICKEFWMAVFRKQVDNLKTNHRGVYVLQDNNFRWFMNASPFLWFPCGLIRGALAGLGY-ATI-PQCTFQIKI Ashgo11 QMLLGAVVRVGQIGFQVGSKV--TELLSNNPGLHFDLLGVMKFICREVWKHLFGKQIDNLKTNHRGTFYLFDYDYQPIRDFAPYLHLPCGVIRGILASLGFGEEFPRGVNFNVQI Aspfu1 DFLLIELVRLESIGYRVGQGL--AERFRDRP--RFDNLDVIKFLCKDLWTILFKKQVDNLKTNHRGVYVLTDNSFRPFARMSAFLWFPCGIIRGALSNMGI-ATL-PGATFQIKT Aurde31 DYLLIELVRLEAVGAHVGANL--VERLRDRA--RFDTLDIVKFICKDVWTAVWAKQIDNLRTNHRGVYVLQDNNFRPISRISLYVAWSAGVIRGALARMGL-QGL-PQCTFQIKL Batde5 DYFYMEVVKLELLGFRVGHGI--AERSKDRP--RFDTLDIIKFICKEMWISVFKKQVDNLKTNHRGVFVLVDNNFKWLSRMA-HLALPCGIIRGTLAGLGV-SAL-PQCTFQIKL Botbo1 DYFLIELVRLESIGYQVGGHL--AERLRDRP--RFDTLDTVKFICKDFWVVVWNKQVDNLRTNHRGVYVLQDNLFKPLSRISLYLAMPCGLLRGALARLGL-QGL-PQCSFQVKL Botci1 DLLLIELVRLESLGYRVGLGL--VERFKDRP--RFDTLDVIKFLCKDLWMLVFRKQIDNLKTNHRGVYVLTDHSFRPFARMSPFLYFPCGIIRGALASMGI-NAL-PGATFQIKS Caeel DILHLEIIKLESIGFRVGRQL--VEKVKESP--KLTELEIVKFICKDFWSSVFGKQVDNLRTNHQGVYVVQDGRFTTLRSFPYFLAFPCGLLRGALAGLNI-RAV-PSVKFHIQV Canalb1 QFLLQELVRVESYGYSLGLKI--AEVLSGN---KVDILDIMKFVCRDVWKCLYNKQMDNLRTNHRGTFVLVDNNYKLISSLNVYLWFPCGVIRGILMSFGI-EAF-PAVVFNIHT Cangl NMLLNELVRIQNVGFQIGSKL--CELLSNNPTISFDLLAVMKFVCRDVWKQVYGKQIDNLKTNHRGTFYLLDYDYKPIQTFAPFLEIPVGIIKGVLSSLGFPKDFPKGVSFHVQV Capow DFLHMEMVKLERIGFQTGQAT--IERCKDVH--RFDQLDVIKFLCKEFWTLAYGKQIDNLRTNHRGVYVLQDNRFRVFANISPYAAFACGMLRGALANLGI-VSL-PSCLFQVKM Catan2 HFLLLELVKLEMLGYNVGQRL--VERLKDHA--RFDTLDVVKFICKEFWTCVFGKQVDNLKTNHRGVYVLQDNQFAWFRGASPYLWFPCGLIRGALAGLGL-STL-PQCTFQIKI Cioin DLLHSQLVQLESLGFRVGVSL--GEQLKDLP--RFDELEVMKFICRDFWSSLYQKQVDNLRTNHQGVYVLQDNAFKLLTHISRYLALSCGLIRGVLSNLGV-KSM-PSAKFQIMV CocheC53 DLLLIELVRLEALGYRVGLGV--VERFRDAP--RPTPLDCIKFLCKDLWTLLFRKQIDNLKTNHRGIYVLTDNTFKPLGRMSPFLYFPAGLIRGCLAALGI-QAL-PGATFQIRT Coere1 --------KLESVGFRVGKRL--AERFPMSR--RLDTLDIVKFVCKDLWMLLFNRQIDNLKTNHRGVYVLQDNKFKWFLHMSPYIWFPCGIIRGILDGFGI-STL-PQCTFQIRV Conco1 ------------------------------------------------------------------------------------------------------------------- Conpu1 EYLLIEAIRLESIGMHIGANI--TERLRDRQ--PFDTLDVVKFVCKDLWTACWDKQIDNLRTNHRGVYVLQDNAFKPLMRLSTYVALPAGIIRGSLGRLGL-PGL-PQCTFHVKL Copci EYFLIEMVRLLAIGSHTGANL--SERLLHRP--PFDTLDVIKFICKDLWNALFNKQIDNLRTNHRGVYVLQDNSFKPIQRVSVYTLMFAGVVQGALERLGYPPTL-PNCTFQVRM Croqu1 EYFISEIIRMDKIGYRVGYVL--AERLKDKS--RIDPLEVIKFICKDLWSAMYNKQADNLRTNHRGVFVLQDYGFRPFLRLSKMLIFPLAVIRGALMNLGI-QSV-PQCTFQIRT CryneH991 GYLLPPTFRIGRIGLMVGGFI--AEKLLARP--PIAHLDIIKFICKDLFLYVYSKQIDNLRTNHRGVYVLQSNAFPPLVPLSTHLIFSQALIQGALHRLGM-NAL-PQCTFQIRT Crypa2 --------RLEMLGYRVGQGL--VERFRDRP--RFDTLDVIKFVCKDLWTLVFRKQVDNLKTNHRGVYVLTDNLFRPFSRMSPFLWFPCGIVRGALAAMGI-NAL-PQAIFQIKT Debha1 HLLVLELVRVENYGFDIGLRI--SELISNQ---KMDILDIMKFVCRDVWRVLYGKQMSNLRTNHRGTFVLVDNSYKLIETMMNYLWFPCGVIRGILMSFGI-EAF-PSVTFNIQT Dekbr2 DFLLNELVRIEQIGFEVGYKI--TDCISEKMEIKLDTLEIMKFICRDVWKVIYRKQMDNLRTNHIGTFILIDNGFRPLLHFQPFLRFPCGLIRGILKSLGI-DSV-PSISFSVQT Dicdi EFFYIEMIKLDKLGFKVGHRL--VERLLDTA--LFELLDAVKFICKVFWTTVFKKTIDGLKTNHKGVFVLTDSKFQWLQHLSEYVQFTAGLIKGAMSNFGF-KCV-STCVFTIKI Dmel DCLHAEIVTLEYIGFTTGYRL--IERLREVS--RFDELETMKFICTDFWMLIYKKQVDNLRTNNHGMYVVQDKAFRFLTRISKFVAFTCGLVRGALSNLGI-NSI-PACKFHIEV Enthi ------------------------------------------------------------------------------------------------------------------- Falba DLLHMELVEIEAIGSAAGARFFASESI------HLGPTDAVRFVCNGLWPCFFQNNISNLRSNRLDVFVMTDSAYRPFTWCSPYTWFACGAISGALAASGW-KC--PGCDFVVVI Fomme1 DYLVIEMVRLEAIGVHVGGNV--AERLRERP--RFDTLDAIKFICKDVWSTCWDKQVDNLRTNHRGVYVLQDNQFKPISRISIYVALPVGIIRGALARMGY-HAI-PACTFQIKL Fusgr1 DFLLIELVRLEMLGYRVGQGL--VERFRDRP--RFDTLDVIKFLCKDLWTLVFGKNIDNLKTNHR-----------------SALNRSCG------------------------- Galma1 DYFLIEMVRLEAIGMHVGANF--SERLRDRP--MFETLDAIKFICKDIWAACWDKQVDNLRTNHRGVYVLQDNAFKPITRLSLYAAMPAGIIRGALSRLGY-NGM-PQCTFQIKL Ganpr1 --------KLEMMGYRVGQAL--VERLRDRP--RFDTLDVVKYVCKDLWTAAFRKQIDNLKTNHKGVYVLTDNNFRWLLRMSPFLAFPCGLVRGALANLGI-SAI-PQCTFHVKI Gloin1 EFLIMEMVKLEMLGYQVGQSL--VERFRDRP--RFDTLDVVKFICKDLWSIIFKKQIDNLKTNHRGVYVLQDNGFRWFLRMSPYLWFPCGLIRGALANLGV-VSL-PQCSFQIKI Hisca1 --------RLEALGFRVGQGL--AERFRDRP--RFDNLDVIKFLCKDFWTILFRKQIDNLKTNHRGVYVLTDNTFRPLIRMSSYLWFPCGIIRGGLASMGI-NAL-PSATFQIKT Klula1 QWLLNEMVRLYKIGSGIGSKM--TELLSNNPNLSFDTLGMVRFICKEVWKLLYGKQIDNLKTNHRGVFYLFDYEFQPIQNFAPYIQVPLGVISGILTSLGVPEDFPKGLNFNIQV Lacbi2 DYFLIEMVRLEAIGMHVGGNY--TERLRDRP--MFETLDVIKFICKDIWSSCWDKQVDNLRTNHRGVYVLQDNAFKPITRLSLYAAMPSGIIRGALSRLGY-NAM-PQCTFQVKL Lenti61 DYFVIEMVRLEAIGMHVGANM--AERLHDRG--LFDTLDAIKFICKDLWSACWEKQVDNLRTNHRGVYVLQDNAFKPLTRISVYAAMPAGIIRGALSRLGF-QAL-PQCTFQVKL Malgl1 ELLWIEAARMEAIGRHVGGNL--TEQLRDRP--RLDTLERVKFVCKELWTVVWDKQIDNLRTNHRGVFVLQDQALKTLAALGMQLAYAAGLIQGAMERLGVPCSL-PICAFHVRV Mellp23 ESFLSEVMRIDQLGYKVGYIL--SEKLKDKP--RLDSLEVIKFICKDLWLSIFNKQVDNLRTNHRGVYVLQDYGFKPFLKLI-MLVFPSGIIRGSLMNLGI-QSIPPQCSIQIRT Mnele ------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------- Morel2 EFLTTEMVKLEMIGFRVGERL--IEKIKDRL--RFDNLDVVKFVCKEVWMFLFKKQVDNLKTNHRGVYVLQDNGFRWFTRMAPYLWFPCGILRGILSNLGI-ASL-PACTFQIKI Mucci2 DLFLIEMVKLETLGYAVGQRL--VERFKDRP--RFDTLDVVKFICKDLWTIMFKKQIDNLKTNHRGVYVLQDNGFRWFMRMSPYVWFPCGIIRGALASLGV-PTL-PQCTFQIKI Mydma DLLHMETVKLEQMGFRVGHSL--IEKFKDMT--RFDELDIMKYICKDFWVLLYCKQIDNLRTNHQGVYVLVDSNFKLLNKITKYIAFPCGLIRGSLAALGV-TSM-PTVKFQVEI Neucr2 DFLLIELVRLEGLGYRVGQGL--VERFRDRP--RFDTLDVIKFLCKDLWTLVFRKQVDNLKTNHRGVYVLTDNSFRPLSRMSPFLWFPCGVVRGALAAMGI-TAL-PAAVFQIKT Orpsp11 ------------------------------------------------------------------------------------------------------------------- Pench1 DFLLIELVRLESLGYRVGQGL--AERFRDRP--RFDNLDVIKFLCKDLWTVLFKKQVDNLKTNHRGVYVLSDSAFRPFGRMSAYLWFPCGIIRGALANLGI-NTL-PGATFQIKT Phybl2 DFFLIEMVKLETLGYAVGQRL--VERFKDRP--RFDTLDVVKFICKDFWTIMFKKQIDNLKTNHRGVYVLQDNNFRWFMRMSPYVWFPCGIIRGALANLGV-PSL-PQCTFQIKI Picst3 QLLLQELVRIETYGYSLGLKL--AEVLSGT---KLDILDIMKFVCRDVWKCLYNKQMDNLRTNHRGTFVLVDNNYKLIQKLNVYLWLPCGIIRGILLSFGI-ELF-PAVTFNIHT Plicr1 DYLLIEMVRLETIGLHVGANF--TERLRDRP--LFETLDVIKFICKDIWAACWDKQVDNLRTNHRGVYVLQDNAFKPISRLSLYVAMSAGIIRGSLSRLGF-HGL-PQCTFQIKL Polpo EFLYIEMIKLEKLGYKVGHKL--VEKLIEQQ--LLEVLDVVKFICKVFWIAIFKKSIDSLRTNHKGVFVLTDQRFQWLLHLSDYVYFAIGLIKGAMANFGY-KSI-HSVVFTIKL Pucgr2 DYFLNEMIRMDAAGYKVGWSL--AERLRDKP--RIDPLEVIKFICKDIWTAMYNKQVDNLRTNHRGIYVIQDHSYRAFLRVS-MVIFPSAVIRGALMNLGI-QSI-PQCTFQIRT Punst1 DYFLIETVRLESIGAHVGANL--AERLRDRG--LFDTLDSVKFICKDVWIACWDKQVDNLRTNHRGVYVLQDNAFKPISRLSLYVALPAGIIRGALTRMGFANVM-PSCTFQVKL Rhior3 DLFLMEMVKLETLGYLVGQRL--IERFKDKP--RFDTLDVVKFICKDLWLILFKKQIDNLKTNHRGVYVLQDNGFRWFMRMSPYVWFPCGIIRGALASLGV-PSL-PQCTFQIKV Rhoto1 EFFVQETIKLEGLGFKVGWAT--AERLRDRP--RFDPLEAIKFVCKDVWVSVFDKQVDNLRTNHRGVWVVLDTSLRGLRGVSLTLSFPSGLIRGALSALGI-SSL-PQATFQIRT Rozal11 DFLLSEIIKMDSIGYRVGYSL--STQLKDKP--KLEDLDAVKLLCRDLWSLIFGKQIDNLKTNNRGTFVLQDYCLGWLENKY-------GLIYSKL--------I---------- Sacce1 QMLLNEMVRLRNIGFQIGLKL--SELLSNNPNLKFDLLLIMKFICRDVWKQIFGKQIDNLKTNHRGTFYLLDYDYRPIQSFSPFLEIPVGIIRGVLSSLGYSSEFPKGVSFHVQV Salro EFLVAEICHVEAIGYRTGLAL--FESHEAKKNMRFGELDVIKYLCKDMWQVIFQKQIDNLRTNHKGVYVLHDNQHPMLTHLPLLLAYPCGVIKGGLAALGI-TAL-PACKFNLDV Schco3 DYFVFEAVRLEAIGMHVGANF--TERLRDRP--LFETLDAIKFICKDIWAAFWDKQVDNLRTNHRGVYVLQDNHFKPIIRISIYTAMPAGIIRGALSRMGY-NAL-PQCTFQIKL Schpo1 DFLLIELVMLESIGFQVGRKI--TERLLNRN--RIETTDVMRFLCRELWPIVFRKPLDNLKTNRRGIFVLTDTYFYWFTKMTPYFYFPSGFIRGVVYTFGY-SAL-PTCIFHVKF Sorma DFLLIELVRLEGLGYRVGQGL--VERFRDRP--RFDTLDVIKFLCKDLWTLVFRKQVDNLKTNHRGVYVLTDNSFRPLSRMSPFLWFPCGVVRGALAAMGI-NAL-PAAVFQIKT Sphar EFLHMEMVKLEKIGFSCGQSL--AERLQDTP--RMDQLEVIKFICKDFWMNLFQKQVDNLRTNHKGVYVLQDNKFQTFAPIAPFLAMPCGLIRGALAALGH-TAM-PACTFQIRI Spipu1 DLLVLEMVKLESLGYRVGMAM--VERIRDRP--RFDTLDAVKFICKDYWIALFKKQIDNLKTNHRGVYVLTDNNFRWFLRMSAYLAFPCGLIRGALANLGV-ASI-PQCTFQIKI Sporo1 -----------------------------------DTLELIKFICKDVWVSLFDKQVDNLRTNHRGVYVLLDNRLRFLERLS-LLKFPEGVIRGSLANLG--------------- Stehi1 DYFQIELVRLEAIGLHVGANI--TERLHDRP--IFDTLDTIKFICKDLWATCWDKQVDNLRTNHRGVYVLQDNAFKPVARVSLYVAMSAGILRGALMRLGI-QAL-PQCTFQVKL Tapde11 ELLMIEMTKLESIGYRVGHGL--VERLKDRP--MLDHLDIIKFVCKDLWTVLYHKQIDNLKTNHKGVYVLTDNQFRWFNKMSAYLWFPCGVVRGALANLGM-DSP-PGVTFQIKT Thetr ------------------------------------------------------------------------------------------------------------------- Treme1 TYLLPCVYRLERIGLMVGGYI--AEKLLARP--PLSQLDVIKFICKDLFLFVYSKQIDNLRTNHRGVFVLQSHIFPPLASLSMHLVFPQALIQGALARLGL-PCL-PQCTFQIRT Trire2 DFLLIELVRLEAQGYRVGQGL--VERFRDRP--RFDTLDVIKFLCKDLWSLVFGKNIDNLKTNHRGVYVLTDNAFRPFSRMSPFLWFPCGIIRGALAALGI-SAL-PAAIFQIKT Umbra1 DFLMMELVKLEMLGYRVGQSL--VERFVDRP--RFDTLDVVKFICKDLWVIMFKKQVDNLKTNHRGVYVLQDNNFRWFMRMSPYLWFPCGVIRGALANLGV-SSL-PQCTFQIKI Ustma22 HSLATEMVRLEGIGYQVGYHM--TENLRDRV--RFDTLDVLKFVCKEVWTAVWGKQVDNLRTNHRGVYVLHDNQFAPLKHVSVFLSYPVGIVKGALAHLDV-PSA-PQCTFHVKT Walse1 DLLTIELIKLKHVGTSIGHTV--AERIQTRE--PLDNLEVIKLLCKEIWTFIYGKQLDNLRTNHKGTFVLHDNSYRPLVNLSIFLSIQLGIIQGCLSAFNL-SSL-PGCTFQVKL Zygro1 MMLLNECVRLRNIGFEIGNKI--TELLSNNPNLQFDLLSVMKFICRDVWRQMFNKQIDNLKTNHRGTFYLFDYDYQPIQSFAPFLEIAVGVIKGVLASIGHAPEFTKGVSFHVQI [Cluster2387.fasta_al_trimmed; alignment length = 271] Allma1 LKMLMKMGYTPGTALGSKGEGIVEPI--QV-VK-R--P-Q-GMGIAYLTAQDVLDHVIDMRADSVLDPTADLGSHDLRQRALQRDRDRDLRGLRAAQKSQLTDLIARALACSLVTPHLRV-LLADWDPLSRTVVRRIKSAVYDALLWLPRVRAAVTAQWSVHD--PAPLLALSVLTPSIYHYIVQHLVLPRLRMAVDGWSPRPWLESVHFRLVYKLTVYLINP-AH-QD--LIPASLLAKVLFTQWLDV--LHQWLEVGEWAQPYFAAALE Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ARMMAKMGYKEGQGLGASGQGIVAPI--EA-QA-R--P-T-GAGLGFRTAREIEADLIDATGLTSTAGLARRARHDLEAFADEWKGLTERAQIVEQLDDQLTNLITAITAVAAIHPLFRQ-AMEDWDPLQVSNLRRLQPLLYETMIWLPRVRSALINDWDVYD--PSPATSLEILPNFVFANVLDQLVVPKLSSGLKEWKPRTWL--QYLDAKKKFREILVNP-QD-QD--LVLGLLLVAEFFPKWHKI--LYIWLEVGEWVDDEWNKGLQ Aurde31 ARLMAKMGWQAGTGLGSSGEGIVTPI--ET-KL-R--P-N-RVGIAHKTYEQILADIIDATGLTSLAEMVDMCKGELDGLAREARALEERARLRKKMAARLQNIHLIVIVVASVAPAVRR-DLASWHPLETAVFAQWQPALYDSLLWLPKVRSSLNNDWSADN--AAPAIRLTLLPPFIRDNLLDQVVLPKVQKAVADWSPRPWL--PHVGAKRKVKSIFINP-RD-QV--LTFAALLDQEFFPKWLGV--LHTWLEIAEWVKAGLARGLK Batde5 SKMLAKMGYVPGTGLGANRVGIIAPI--DV-KL-R--P-S-GMGLGFKTAQDLLQEIIDMTSLSNISEAKDLAQSDLLYVSRKKHHESTLNALEALLKERLGRI----LIVATLMPWFKA-MLCNWSVLEADVVKRWKRFLFESMLWLPKVRQAINNDWNVYQ--PDSLVAFSILPTWLFQNIACQLVIPKLKRAVDMWEPHPWL--PILGVRRKLEYCWLSP-AN-QD--LLFSHLIATEFFAPWCRM--LWTWIEVSNWVADGWRTALD Botbo1 AKLMAKMGWQAGTGLGASAQGIVTPI--ET-KL-R--P-K-NMGIAHKTYEQIVQEIIDATGVSSMADLVDVTKGDLDGLAKEAKALEERQRLRKSVASRLQKVHLVVIVVAAIVPVFRR-SVSAWDPLKADVLRQWKKILFESLLWLPKVRSAINNDWSPKT--PTPLVQLDVLPQFMIDNILDQLVLPKVQKAVSDWSSRPWL--PHIGARRKVKSLFINP-RN-QN--MIFSHLLEAEFFPKWLDI--LHIWLEVAQWVRNGFTKGLQ Botci1 ARMMAKMGYKEGQGLGKEGQGRSGVI--EV-TL-R--P-Q-GVGLGYRTVEEVQRAILDMTGLTSTSGIARRAQNDLSAFVEEWKNLEERIQQQQELDEQMKLFAESIIAVAAVHPFLRQ-ATEGWQPLEVPNLYKIRHILYESMIVFPKIVSSINKSWDVYN--PAPVLAFGLLPKFVGSQILDQAIVGRLNDAVSSWNPKPWL--QHLSVKRKFRHLIVDP-ND-QSPYMVVGQVIVDTVFPMWHHV--LHQWLEIGQWIQEEFEKGHE Caeel MKMMQAMGYKPGEGLGAQGQGIVEPV--QA-QL-R--K-G-RGAVGYRTIEDVMEEVIDMTGYSGYDSFVDLTEEGIRRSNQQLISLKDQQQVQKSLGQHIKDVYELIVAIPTVLPLIQK-YFVAWKPLECELISTWRDILYDRIIILPSIRRAC-LQWDPSTQ-MHEMIELPLLSAWITENILEQLVVPKIAERVNQWDPMPWL--VLLGIRQKLSKALMNP-EY-PE--WAIANIVTKYFFPRFYNC--LCLWLEVKRWVNENLRRSMI Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow SKLLKKYGYVEGAGLGNAGEGMAVPL--DV-QK-R----Q-GKTLG--TATQIIANIVDLRGAPSLSGQVDTFATELESFASKVPMEQAH--AQEHKSERVREISEILIALSYATPAVSA-ILNDWRLFGVDLVRSWKQLLYDRLMWVPHLRTSLM-RW------SPRTSSLDLIPEWIGENLCDQLLVPRLIADVENWNP-PFL--PLLGIRFKLSNALVDP-AN-QR-TVPLVGVLERELFPRWHQA--LTAWLEIAEWISAQLTVALD Catan2 LKLLMKMGYTPGQGLGAQGQGIVEPV--QA-VM-R--P-K-GMGIS--QEEDVMD-IVDLRGAAATSPYATLTQSKLAARQAQRVADQAKAESKTKHESKIHTLADRIVA-SLAVSKLRSQFTPDWDPIASSQLERIRSG-YDSVMWIPR-----------HA--SQSVVDASLVSPALHAHVVHQICVPRLRRALDTYSPSPRAPPAHPT---------IDP-AA-QD---PVAHCSHTCL---VVRV--THAWAELAAWVKVYLGAGLM Cioin MKLLTKMGYKHGKGLGKGNQGIINPI--EA--L-K--R-TKKAGLGYKTVEELTKSVIDMTGFTGYHAIIEDTEQKILLADRQKRYESDRTKLQETLTNRIETVLRTILASVMVYPLITK-YLANWNPLNINEMKRWKLLLYQHMMWMPHVRSSI-LSWDPHD--ADPVLNLPLLPTWMMENLLTQLVLPQLQKEVDCWNPLPWL--PHMQIRHKLSLALVDP-RK-QD--LSMVGILEKHFFNKWLKA--LSAWLEVTQWVKDRLKQALE CocheC53 AKMLAKMGYKGEGGLGKEGAGISEPI--QV-VN-R--G-T-KGGIG-KTLYELEA-IIDA-----TTGASLQARDALEDMA---AAFAELRRIVSQ---------------AYTHP--------------------SEALVYESMMWLPAVSSAV-TQWDVKH--PRPLLRLPVLPPFVGKRVLEQ-VTRKLSTSIHEWNPREWL--PFLGIKRKIRHALIDPNEQ-QD--VVIGELLRAHFFPRFLAI--LHQWVEVRAWVESGWKEAYT Coere1 --MMAKMGYRHGEGLGKHGEGRVEPV--QV-KL-R----RAGEGISYKTLEEIELRFVDMRSAGSLTELLDLAFGRLEDLVRERDAEVAKASLKRCVAEGLHAIEEAIVVTDSIHTHFAH-LFRAWDPTTASLTTPLLPFVFESLLLVPRLKQYIYTEWDSST--DSLSTTFACLPPVVVAEI-SATLAASLQRSVEAVNPRPWL--PFISVRRKLSTAIFNA-RK-QT--LIWLSLVRRTILQDFLDY--LRRWLEIADWIQDAFKTALV Conco1 LKFLKKFGYKEGQGLGSKGQGLAEPILPNV----R--K-DYKAGIAFKSFRQTLDE-IDQRN---MDEI----EDELIELNDQLTALEIRKIASIELE--VEIIETSIAAVACIIPNFKR-VVTQWNPLQSTFLSNYPNLFFDSLIWLPKVRSTIVNQWSPQN--YDSAIRMRLVSSYIFELVINQSIIPKMQLAVENWDPKPWL--PLIHIRSKLGLTLINP-SN-QN--INIEKILKDAFFPKFNDV--LKDWLEVFDWVDHSFRLALD Conpu1 ARMLANMGWQSGTGLGAEGQGIVIPI--ES-KL-R--P-K-NMGIAHKTYEEIVAEIIDATGVSSLADVADACKTDLDGLAREAKSLDDRARLRKKVSSRLQRVTLVVIVVAAITPLVRR-AVVSWDPLIASTFRTWKAALFESLLWLPRVRTTVNNDWDPYD--ATPAVKLSFLPPFVRDNILDQLILPKVSKAVADWSPKPWL--PHLGAKRKLRSVLINP-RQ-QD--MILTQIFESTFFPQWLDV--LHVWLEVAQWIERGFTRGLQ Copci ARMLAKMGWQAGTGLGAEGEGIVTPI--ES-KL-R--P-Q-KMGIAHKTYEQILEEIIDATGVSSLSEVADACKSDLDGLAREAKALQERARLRKKVDSRLQQIQLVAVVVAAIAPLLRR-LVSTWNPLELTVFKDWRRALFESLLWLPKVRTIVNNEWSAES--PQPAVKLSLLPQFIRDNMLDQLFLPKVQKAVADWNPKPWL--PHIGARRKVKSLLVNP-RA-QN--MIFSQILETEFFPKWLDV--LHIWLEVAQWISRGFTRGLQ Croqu1 LKMLEKMGWKSGTGLGAKGEGIVTPL--ES-KV-R--P-K-GMGLSHRTYEEIINEIIDLTGSTTLLHHCDMAKGNLINLAKEGTAIKRKAKSTEIMKKNMKKIMTISIVVCALAPILRR-AWRDWDVLLVAELKRFKKCFYESLIWVPKIRSTV-NTWSPSD--SEPMIELPLLPQFVRDNLLDQLIVPKLLSSIASWDFRPWL--EHIGVKLKLATWLINP-KQ-QD--LILNQLYS-EFFVKWLET--LWIWLQIGQWIQLGFARGLE CryneH991 ARLLAKQGWEAGKGLGVQENGRAVPV--EV-GK-V--L-R-GQGIQHKTYEQLLAEVLDARGVQSLSSLVEAAKQDVSGLVREGKKVNEREISRAKAESRLKEIQEIVVIVGAIGQILRN-AFTEWRPFDLSSLKTWRRAYWESLI----------NEWDPLS--PNDAVHLPILPLFVKDNILDQLVLPKVKVAIEQWDPKPWL--PLLGAKRRIRHVMINP-RK-QD--MMFSHLLEVEFFPKWLDV--LYIWLEVATWVKQGFESGLN Crypa2 ARMMAKMGYQEGHGLGARGDGRNVII--EQ-NL-R--P-Q-RAGLGYMTMDEVRKAILDLTGLTSSSGLVKRAQNDFMAILEEWQGLQERRQEHQELEESHQLLASIFTAVSALHPILKE-MVENWNPLQAADLKSIGGLLYESMMWLPHVSRSV-RDWNVRD--SDPMIAVSVLPGFVKTYYLEQDIVRKLEDAVAKWEPKPWL--QHLPVKRKFRQLIVQP-SD-QEPYLMVAEVIAAEVFPKWHDI--LYQWLDIAQWVASEFEKGLH Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi AALLSKMGYKGTGGLGRDGGGMVEPI--KV-QV-R--P-K-NAGLAYDFDEHLESTVIDMRGYTGMEEILKLKQIDIQNQDNKIKHENDKEKLKLTIEKKVTEILETILQKELLEPLLKE-KLNQWELESSKEMVKWRQLFYFLIMFLPKFKNYLRSQWDVKK--PSNAATLDTLPDVIQEALLEQSILPKLKVAIEKWDPRPWI--PLLGIRQKIISALINP-SN-QKSPITIICILEKDFFTRWLKI--LLEWLEISNWIKSIFNISLN Dmel AKLLLQMGYEPGKGLGKDLQGISHPV--QA-HV-R--K-G-RGAIGYKSVEEVIAKVIDMTGLSGYHALVSQCEQQIIAIDNQERECSSQRKLEEIVQESLERVERLILAAGVIAPLLKR-ELVQWQPLELPLIKKWRGMLYSSLIVMPSFRSSA-AAWQPKE--HPPMASLPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLPWH--AILGIRSKLGIALINP-MH-QD--LYMAQLLDRHFFPRWMQV--LVVWLEISRWVKEHLRRALE Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MKLLLQMGFQPGRGLGKHGQGLVEPI--KA-VV-RDPQ-A-GLTIDFRTLEEIRAA-VE---AAALAGDVEHDYESLQEATDHLERARAGTQCQAQREQRLADHVARLAALPYFAQRMAA-GAEGWALPL---LATWRPLLFDLIVWLPTVRSAIINEWNPTCTVSTKLMS-DLLPPTLQVHLLTRLVLPRVEEACRSWRPG--------GRFAGLSPGRVPL-TD-WR-TFPAERGPTGEAILRVAPADPACTLVKLAHLVLPQWMTVLD Fomme1 AKMLSKMGWQAGQGLGTEGQGIVAPV--ES-KL-R--P-K-GMGIAHKTYEEIIAEIIDATGVSSLADVTEACKVDLDGLAREAKALEERPRLRKKIERRLQAVHLVVVVVGAIVPTFRR-MMASWRPLDTSTLRRWRQAFYESLLWLPRIRSTVNNDWSPSH--PAALVKLDVLPLFIKDNILDQLILPKVSSAISNWSPRPWL--PHVGARRKVKSMLINP-RN-QD--MITGQLLETEFFPKWLDV--LYIWLEVAQWVEGGFTRGLQ Fusgr1 ARMMAKMGYEEGKGLGKEGQGRNVII--EA-NL-R--P-Q-GIGLGYLTAEELKATILDMTGLTSTSGIVKRAQADLLAFSDEWKSLQERKEKEQEMDERLQVFSELVIAVAAIHPFLRE---AEWDLLQASGIKELLPLLYESMMWLPKALTAV-RSWDVLD--PAPMLSADLLPVFVRAQFI-DNIVRKLETAVSDWNPKPWL--QYLPVRRKFRQLIVEP-SD-QEPTLIVAEVLMQHMFPMWHRI--LVEWLEVAEWVKAEFDKGMK Galma1 ARMLSKMGWQAGTGLGVGGEGIVIPI--ES-KL-R--P-Q-KMGIAHKSYEQILAEIIDATGVSSLADITDACKTDLDGLAREAKTLQERLRMRKRIEARLQQIQIVAIVVGAIAPSMRR-MVANWNPLELPTFRSWRRALFESLLWLPKVRTSINNDWSPDE--PQQAVKLTFLPPFIRDNLLDQLFLPKVQKAVANWTARPWL--PHVGARRKIKNLLINP-RD-QK--MIFSQILETEFFPKWLDI--LHIWLEVAQWINRGFTRGLQ Ganpr1 SKLLRAMGWKPGQGLGKDRAGMVKPI--DV-KL-R--P-Q-RAGLGYITPADLLAAIIDLTGISSLSTVADLARSDLVSAGRALRAEDAQS--AAQTAAEV-AVAELALAVSAAQPVLAR-LWRTWDPLSLAWLSRWGTLMYEALLWLPPLRSA-ASRWDPGA--PESMLKVPVLPAWLHHHVLDQLVLPKLVRFVALWRPSPWLAVPNPPARRRLEGELVNP-AS-PD--LLTSALIAVELRPKWMRA--LWTWLEVARWLEKLWREALD Gloin1 LKLMQKMGYKIGEGLGSDGRGIVNPI--ES-QP-R--P-A-RMGLAYKTADEIINEIIDMTGISSTSQIVDLSKADLEHFTRERHVQTERARVTAQVNKRLGEIMSIIAVIAIITPVIKQ-NMIDWDPLELSLEFQKWKGLYESMMWLPKIRSAINNMWNARD--YDPAIKLPLLPVFIYDNIIDQLIMPKLTREVDSWNPNPWL--PLLRIRQKFRSSLINP-KN-QE--L--------------------------------------- Hisca1 ARMMAKMGYQKGQGLGASGQGMLNPI--ET-VL-R--P-Q-GIGLGFRTAREIEADLVDATGLTSTAGLARRARNDLEAFADQWKALVERDEVVAELDGQLSSLSLAVLAVAAVHPLFRE-SMEEWEPLNVSNLQRLQPILYETMVWLPRIRSAILNDWDVHD--PSRATALDVLPEFICSNVLDQLIAPKLSTAIKEWKPRDWL--RYLDAKRKFRLMLVNP-QD-QN--IIIALLLTAELIP-----------------C--------- Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ARMLAKMGWQAGTGLGTTGEGIVTPI--ES-KL-R--P-Q-KMGIAHKTYEQIIAEIIDATGVSSLADLADTCKGELNGLAREAKALQVRARLRKKIESRLQRVQLIALVVAAITPLVRR-MVTAWDPLKISTFRGWRRALFESLLWLPKVRTTINNEWSAEN--PQPAVKLTFLPPFIRDNFLDQLVLPKVQKAVSDWNPKPWL--PHVGARRKVKSLLVNP-RD-QK--MIFSQLLETEFFPKWLDI--LHIWLEVAIWVSRGFTRGLQ Lenti61 ARMLEKMGWQAGQGLGTTGEGIVTPV--ES-KL-R--P-K-GMGIAHKTYEEIISEIIDATGVSSLADVTESCRTDLDGLAREARALEERARLRKQVDARMQQMNLVVVIVAAIAPVVRR-MLTQWQPLETASFRAWRRALYESLLWLPRVRSSLNNDWSPED--PLPAVRLPFLPPFIRDNFFDQLVLPKVHKAVGDWNPRPWL--PHVGARRKVKSVLVNP-RQ-QD--MILSQILEKEFFPKWLDV--LHIWLEVSRWIAQGFTRGLQ Malgl1 AALMRQMGW-SGGGLGKHGTGIVNPI--EV-KM-R--P-N-RAGVAYRTYDEMVAEILDARGVDSVAAACRQSKEALDRLARHGAGIREREALRVRAEERLTSVMHVIAVAGALVPALRH-TFADWDPLAVQRLASWLCFLWESVLWMPVIRSALTNTWDVHD--AAPAVALDILPPFVLDNVLDQLIIPKLERAVQGWTPNPWL--PI-GARRKWRSVLVDP-GQ-QD--MVLNRLFETEVAPRWLDI--LHAWIEIAAWVTCMFRQALQ Mellp23 LKMLEKMGWKSGTGLGAKGEGIVTPL--ES-KV-R--P-K-GMGLSHRTYEDIISEIIDLTGSTTLLHHCDMGKGNLINLAKEGSAIKQKAKSAEMMKNNMKRIIAISVAVSALAPILRR-VWQNWDVLQVAELKRFKKCFYESLIWVPKIRSTV-NSWDPVQ--CEDMIEVPLLPQFVHDNFLDQLILPRLVSSIDSWRFRPWL--EHLGVKLKLATWMINP-KQ-QD--LILDGLFS-EFFVKWLET--LWIWLQIGAWIRVGFARGIE Mnele SKLMAKMGYEPGKGLGKEGQGLVEPV--KA-HL-R--K-GRRTGMSYKTVDQVLSEVLDMTGYEGYGKIVDMTESDLLSNHKKLQYEKDTEKKEKVIEDSLIDITQVIVAIPLLYPRLKA-LMKPWQPPVIDYFVTWRELLFHHLLWMPYIRQAV-QNWNVRD--SAQLIKLPLLPSWIVNNILYSLLLPKLRNEVDLWNPTPWL--PVMGIRQKLGNALINP-NH-QV--LHLASLFDKQFFPKFTAI--LKTWLEVIMWVRTNFHHCLD Monbr MKLLAKMGWKPGKGLGVAEQGISSPI--EV-NSNR--R-R-NQGLQYTTAEDLLQTIIDMTGIDSTSGVVSMAETELMRLDMRVKQEEQQEEMNTKLTETVAALLTALILKSALEPALIR-RLQTWRPLQVATFAQ-ARLEYEHLLFLPRLRTAIMADWDPRT--NSEAAALPVLPGWLLEHVLRQLVLPRVQRAVEEWDPRPLV--EVLGLRYKLMSCLVDP-SN-QD--LTLIPLLVRHLLPKLLRT--LCQWLEVMKWVKREFMAMLK Morel2 LKMLEKMGWKKGYGLGAGGSGIVEPI--QT-KL-R--P-V-KMGIGYKTAAEIQQEILDMTGLTSASQIADISTTDLEQVARTQKADHIRVRIQQQVDERLAKVMTITVVVAAIQDAFKK-LFKGWDVLKAGLFRKWQKLFYESLLWLPKVRSALNNAWDPRD--SDPVIELPVLPLFMQDNIITQLVLPKLHKEIEKWSPRPWL--PILGVRRKLSSALVNP-RD-QK--ITFSSLLVNEFFPKWHQV--LYLWLQVSQWVATGFRQGLD Mucci2 ------MGWNVGKGLGADGEGIINPV--ET-KL-R--P-A-RMGLSYKTAAEILAEIIDMTGI-NLADIVDLSRADLESLSREKQTNAFRGAIRENLDRKLEQLKVIVMVISVWAPIMKY-KAMRWNVLEVADVKKWRALLFETMMWL--------NKWDIHD--PDPLIQLPVLPRFIHENIIHQLILPKISRAVSDWNPRPWF--PTLKIRHKLSVVLVDP-RN-QN--LVLGLLLKNEFFNKWHAV--LVQWLQISDWVMQEFRRGLE Mydma SKMLEKMGYK-GKGLGKHGEGITEPI--EA--F-K--R-GGRAAIGYKTAEEVKKSVVDMTGLQGYNAIVDLAESEIIQIDRQLRFEKDNERLDKVVQNNLEHVLRIILVVPLGFPLLAR-HFSSWQPFSIEYVKLWKNVLFERIIWMPHIRTAI-GIWQAKN--PDPLISVQLIPDWVVANILDQLILPKLQAAVEFWNPLPWL--PLMGIRHKLSAALINP-HQ-QI--LHMVSILEKHLFPKLLQV--LRKWLEVTKWIKEQFNRALA Neucr2 ARMMAKMGYQEGKGLGKEGQGRNVII--EA-NL-R--P-Q-GAGLGYMTLDEVKKVILDMTGLTTSSGLVRRAQNDFMAILEEWQNLQERKQEQQELDQANRAITGLCLAVAAVYPALRE-YLQIWKPLEVDGLMSIRKLLYETMMWLPSVASAV-RTWDVRE--PDQLIAVGLIPSFIRSQLL-QDIVRKLEEAVQKWHPKPWL--PYLPVKRKFRQLIVDP-RD-QEPYMMVGEVIVVEVFPMWHDA--LYQWLQIGQWITAEFEKGMK Orpsp11 ----------------------------------------------YKTVDEII-QIVDMTKLSDTSQLTDLTQADLLYILKQLKIEETKLQKSDQLKEKVKKIDSIILIVTVINPIFKK-MIADWNPLKIDYFIKWKKLLFESLLWLPKIRQTINNDWDPKN--PDALIKLAVLPQWLKNNIIEQLIIPKLKHEVDQWIPQPWL--VIIDLFESVKNKLINP-AK-QD--ILMTKIIITEFFPKWYKI--LAMWLEIAAWLDDYWKQGLD Pench1 ARMMAKMGYREGQGLGTTGQGIVNPI--EV-QA-R--P-Q-GAGLGFRTAREIEDDLVDATGLTSTAGLTQRARNDLEAFADEWKGLKERAQVVDELDNHLTGLIAAVTAVAALHPLFRQ-AMEEWEPLQVSNLTRLQPLLYETMIWLPRVRSALLNDWDVYD--PSKATALAIVPPFVYANVLDQLVVPKVGLALKNWKPRTWL--QYLDAKRKFRSVLVNP-QD-QD--LVMGLLLVSDFFPKWHEI--LYIWLEVGTWIDDEWNKGLQ Phybl2 QKMLEKMGWAAGKGLGAGGEGIINPV--ET-KL-R--P-K-GMGMGYKTANDILSEVIDMTGV-SLADIVDLARGDLENLSREKQANVFRVDIQKNMEKRVEEIKNIGMVVAVWAPILKY-KCVHWDVLDVDDVQRWRKLLYETMMWLTKVRSAINNRWNVRQ--PEPLIILPLLPRFIFENIINQLLLPKITTAVSDWDPRPWL--PILEIRQKLSVVLVDP-QD-QK--IIIGQLLEHEFFPMWLNM--LYNWLEVGEWVSQCFRKGLD Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ------MGWQAGTGLGAAGEGIVTPV--ES-KL-R--P-Q-KMGIAHKTYEQIVAEIIDATGVASLADVGDACTSDLDGLAREARALEERIRLRKKVESRLQQVHLVVVVVGAIAPIFRR-MVTQWHPLEITLFRSWRRALFESLLWLPKVRSTINNDWSPQD--PHPAVRLSLLPPFIRDNFLDQLILPKVHSAVADWNPKPWL--PHVGARRKVKGLLVNP-RA-QD--MVFAQILETEFFPKWLDV--LHVWLEVADWIANGFTRGLQ Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LKMLQNMGWKSGTGLGTQGEGIVTPL--ET-KA-R--P-K-GMGLSHRTYEQIISEIIDLTGNTTLTHHCDISKGSLIHLAKEGQAIKQKARSEQILKSKIKRIVELTIVVSALAPILRQ-VWSRWDVLRVKELKRFRKCFYESLIWLPKIRSAV-NVWSPYQ--SEEMITISILPPFVHDNFLDQLIVPKLLTWIGNWDFRPWL--ELVGVKLKLSAWLINP-KN-QN--LILDQLLTNEFFSKWIDT--LWIWLQIGEWVSLGFATGQE Punst1 ARMLAKMGWQAGTGLGATGTGIVTPV--ES-KL-R--P-K-GMGIAHKTYEEIVAEIIDATGVASLADVVESAKGDLDGLAREAKALEERARLAKKVQKRLQEISLVAIVVAAIAPAFRR-MLASWNPLEVNTFWPWRGILFESLLWLPKIRSVTNNEWLPEN--PAPLVRLTLLPPFIRDNFFDQLVLPKVQKAVAEWNPKPWL--PHLGARRKVKSLLVNP-RA-QD--MIFSSLLESTFFPKWLEV--LHFWLEIAQWVARGFTQAQQ Rhior3 QKMLEKMGWKVGQGLGASGEGIVNPI--EA-KQ-R--P-S-GIGIGYKTAAEIIAEVLDMTGV-NLADIVDLAKSDLENLSREKQNTSFENTIGKNIERKVERIKEIA----------------------------------------------------------------------------------------------------------------------------------------QWISR--L------------------- Rhoto1 MKLLEKMGWQSGSGLGKEGQGIVTPVGEGQ-KI-R--R-K-GEGIKYKTYEEIVAELVDLTGLSSLPAFCSTLSSSLKSLAREGAGVEQRARVRQLVEERLKEVMQCVVVVAAIAPILRR-LWQSWDPLSVSQLKRFRKLFYETLMWLPKVRSAVNNAWLPSE--PQAAVELPLLPSFLRDNILDQLVLPKLSAAIADWSPSPWL--EHAGAKRKVRSWVINP-RQ-QD--LMLSQLIEAEFFPKWGEA--LWLWLQVAEWVSRGFRKGLD Rozal11 LKLLLKMGYKPGDGLGAKGEGMFQPI--DAGKA-R--E-K-KSGLGKNLLDSF---IIDMTG------IVNLCEGKIIELNQQLNQEEEKLEIENQIK----------LFSSILKPLVLR-LLNN------EEEIQFNRNIFDNLILLPKVRQFINSN-DVRD------LKV-IYKECFSNAMFDKLVIK------DVLLPR-WL--FV--LLKNYSTEVINP-AN-QE--LTMMSLFENIFFPNWLEI--LHTWLEISLW---------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro MKLLQKMGWKKGEGLGRARRGIVEPV--QA-KL-R--K-A-KQGLQYVTAERLLSSIVDMTGVRSTMG-LEMAEADVHTWNNKVRGTRRQRELNERLGDSLEQLLEKTLAYATAIDLFAA-RLKSWQPLQVRYLRQWKRILFESLVVLPHVRTALVSRWQPRD--PAPVVALPFLSTTMLDNIARQLILPRLQNAVQAWDPRPLL--PYM-VRYKLGVCLINP-AE-QD--FDVVSLWAGCVFPKLLRC--LCVWMEIADWIQSRLHRALM Schco3 ARLLQKMGWEMGTGLGTTGEGIVTPI--ET-KM-R--P-K-QMGIAHKTYEQILAEIIDATGVSSLADVAESCKSDLDGLAREAKSLEQRSRLRKKVEAALQRVQIVAVVVAAIAPLFRR-LVTAWDPLEISTFRKWRRVLFESLLWLPKVRSAINNSWSPHG--PQPAVKLSFLPPFIRDNFLDQLILPKVRKAVAEYNHKPWL--PHVGARRKVKNMLINP-RE-QQ--MVFAQLLETEFFPKWLDI--LHIWLEVTQWVQKGFTRGLQ Schpo1 AKMLEKMGYKQGQGLGANAEGIAEPV--QS-KL-R--P-E-RVGLGLKSSEEISKDLIDASLTSNKEELSRLARVECEHHASAWQQLQARKRVTTEFDSRLEKLLGKVVAVSILAFVLSE-PIKNWDVWKLESFLSWKNSLYESFMWKKKIGEEL-KKWIIQD--SLKALQLPVVPEKVKDSLIQDDILPRLKDAVSKWNPKPWL--PYLEVLVQFSLILIDP-SN-QD--LVFGQLFADHFFPKWLET--LYQWLEASEWIQQGFSKGLD Sorma ARMMAKMGYEEGKGLGAEGQGRNVII--EA-NL-R--P-Q-GAGLGYMTLDEVKKVILDMTGLTTSSGLVRRAQNDFMAILEEWQSLQERKQEQQELDQANRAITGLCLAVAAIYPALRE-YLQIWKPLEVDGLVSIKKLLYETMMWLPAVASAV-RIWDK--------------PS--RSGT-----------------PKPWL--PYLPVKRKFRQLVVDP-RD-QEPYMMVGEVIVAEVFPMWHDA--LYQWLQIGQWITAEFEKGMK Sphar AKLLEKMGWSKGMGVGKSKEGIVNPV--EA-AI-R--LAK-KGGVGFSGVSRIGQNVIDMTGHANYQEACDFAEGEVQSTAQEMEGVEDNKKLEKTVAESLESILATMLAVGIVFPLVEA-HLKEWVPLRVDLFRLWKDVLYERLLWMPHIRRGL-MYWDPVEQ-SYTALTLPVLPDWVYYNIIEQLIYPKINKCVAEWNPQSWL--PHLGLRQKIMAALVNP----QH---------------------------QVTRWMQVQFKCALD Spipu1 SKLLEKMGWRMGMGLGKEGTGIAAPI--DV-KL-R--P-K-GAGLGYKSAEELVAEILDMTGLSDISEIADLAQDDLLHVGRQMRIEKTRKVISQQVNVRLQAVVELALVVASLAPIVKR-TLHEWQPLAAEAFRQWKKLLYEAMMWLPKVRQAINNEWSPQL--PDSVITLVLLPSWLYQNILEQLILPKLTHEVDNWNPSPWL--PHLVIRHKLVGSLVNP-RA-QD--LLLVHLFETEFFPKWHKV--LWAWLEITMWIVNQFRAGLD Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ARMLSKMGWQAGQGLGTTGEGIVNPV--ES-KL-R--P-K-NMGIAHKTYEQIVSEIIDATGVSSIAEVVDHSVSEIDRLAREARKGRIRARLKKRVTARLQQVHLVVIVVAAIAPVVRR-ILAYWQPLQLSTFRSWRKALFESLLWLPHVRSALNNEWDARD--PAPAVKLEILPAFVKDNILDQLVLPKVKRAVADWSPRPWL--GHVGAKRKLKSMLVNP-RR-QE--MMMGQLLEREFWPKWLDV--LHLWLEVADWVEEGFRKGLK Tapde11 AQMMARMGYKAGEGLGTSGKGIVNPI--EA-HL-R--PGQ-KAGLGYKTAQEIINDIIDMTGLTSASNISQIARKEVEQYAADWQRLQNRSRSRKELIKVQQDLLSEAVVVSLLAPVLKQ-CIFGWEVLSVP---ELKALFFDSLMWFPRIRSTL-IAEDI-S--SDAVLNLPLTPSFLRDQIINQLVMPRLTERIQKWNPRQWL--PYLAVKRKFNLVLINP-SD-QK--LIMADLLKDELFPKWIQM--LYDWLEVSEWVRDAFSHALR Thetr SSLLRKMGWQPGEGLGKDRQGIAEPI--RV-KL-R--P-K-GKGIA-ATAEELAAK-VD-HAVTSLSGSADFIDADLRGAAAKATKARTQTTADEKAD------AAKLLALPLAWPHLTA-AVEAWRPL-IEIFAKWKPLL-----WLPPVKRALVTQWQAGATDSADDPALDELPLHVRAHLIVESVVP--------------------GLGFALTHVVADA-LD------PLRAVVERALAKRVVPT--LKTWIRLLHPLAAEALAYLD Treme1 ARMLAKAGWVAGKGLGMMEDGRAVPV--AA-GK-I--I-R-GQGISHKTYEQLLAEIIDARGVSSMSALLDVGKDDVTAAAREGKMINERERARRRVERRLERISTLIVVVGAIAQILKR-SLNTWQPFELSSLKPWRHAFWETLLWLPKVRSAINNEWDPSK--PQAAVHLPILPPFIRDNIIDQLVLPKVKAAADHWDPRPWL--PLLGATRRLRSAMINP-RS-QD--MVFSHLIEVEFFPKWLDI--LYIWLEVANWIAHGFDTGIQ Trire2 ARMMAKMGYVEGKGLGKEGEGRNIII--EA-NL-R--P-Q-GIGLGYLTADEIKKKILDMTGLTSTSGIAQRAQSDLLAFSEEWRSLESRKQREQEIEERLKAFANVVIAVAAIHPFLRS---ADWDPMAASDLQKLSGLFYETMMWLPRVLTAV-RSWDPLN--PTPMLNIDLLPPFVRAQLM-DNVARKLETAVSDWNPKPWL--QYLPVRRKFRHLIVDP-AE-QELYLVLAEVLVQDMFPMWSSR--LQEWLEVADWVRAELDRGLQ Umbra1 MKMLQKMGWQVGKGLGAEGEGIINPI--ET-KQ-R--P-T-RMGIAYKTASEIIKEIIDMTGLTSLSQVADLSLSDLDHLTREKRLAEVREQLQKRLDKRVDELQRIGMVVSVWAPIMKY-GCVRWDVLSSDLVSRWRRLLFESMMWLPKVRSAINNTWNPRE--ADPIIHLPILPLFIYESIIDQLILPKLSKAVSDWDPRPWL--PTLKIRQKLSVILVNP-RE-QN--LLTGQLLDNEFFPKWLDV--LYKWVEVGQWIKSSFRKGLE Ustma22 SAYLASMGW-TGGGLGRSGQGIVKPI--EV-QV-R--P-E-RAGIAHRTYEEIIAEIYDASSVEDLASACENNAQSLGALAREGAQLKQRERAIVKKKQKVRGALQVVAVVEAITPALRA-IWCGWKPLESRYLCQWKALLFDALLWMPRVRTCLS-TFSARR--PASAIDLPVLARFMFDNIIDQLIVPRLSRSVAAC--DPWL--AVLGAKQRLRSALISA-GETQD--MVMESVVASDFFAKWLDV--LCAWLGMDEWGEVGFAIGLD Walse1 AKMLASMGWKAGYGLGEGGKGIAVPI-EAS-KA-R--P-Q-GAGVGHMTYEEVLETILDLTGTSSLAS-ADESRGQLEGLAREAKVINDRKVIVKTVDERMKSIEIAIAVVGAIAPSFKL-LIGRWMPLSIGELRKWKKGLYESLIWLPRLRAGLINDWEATT--PSKATRVDLLPQFIYDNMMDQLLLPKVMKVIDNWKPSPWL--PYLGSKRKLSSWLINP-RS-QV--HVFASIFSNIFIPKFVDT--LYIWLQVAQWFSEGFKIALD Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2393.fasta_al_trimmed; alignment length = 134] Allma1 TTGDLVAANLHVGHPYILGTREGIHIIDPNQ-TLAHLRRAATLTRLVAANGGLVLFVANRIAQDAAVSGTLTNPDLVILLDVTHPACKEAIPTVAVIDTDVDPRWVTYPIPANDESTVGLALVAKTLAREAAEG Ashgo11 SISKLAAAGVHLGQPYIYGSYKGIHIIDLNQ-TLFHLKRAAKVVEGVAENGGLILFLGTRALRRAAERGTLTNPDLIIVLNPTENALREAVPTIGIIDTDSEPSMVTYPVPGNDDSLRSVSLLVSILAKAGERG Aspfu1 TLELLLASQTHLGHRYIFGIREGVHIISLDV-TAAYLRRAAKVVEEVAARGGLILFVGTRAVVRAAELGSLTNPDLVVCFNPVENLLHECVPTISIIDTDADPTQVTYPIPANDDSLRSVAVIAGVLGRAGEAG Aurde31 TLSALVAAGAHYGHPFAYGVRAGVVIIDLDS-TLPYLRRAANVVRGVAARGGSVVFVGSRAVRKAANRGTLTNPDLVVFLNPLQNAIRECIPTIGIVDSNVDPRIVMYPIPANDDSVRTGELVVGLLSIAGREG Batde5 SLKSLLAANLHLGHPYIYGTRHGTHIINLEH-TLTHLRRAAAFIRQVAMSNGNIVFLGTKITVDAALLGTITNPDVLVVLDYINNAVREAIPVIAVCDTNTDPTLVQYPIPANDDSIAGIKLIAGVLSAASRDG Botbo1 TLSALVASGAHIGHPYTYGHRAGVTIINLDH-TLPLLRRAANVTRAIAQANGTVLFVGTTAVRKAAERGTLTNPDLVVFLNPAQNAIRECIPTIGIIDSDVDPRIVMYPIPANDESIRTAELVAGVISIAGREG Botci1 TLELLMASQSHLGHRYIYGIRQGVHIISLEE-TAAHLRRCAKVVEGVAYHGGLILFVGTRAVVKAAELGSITNPDLVPSLYSAHN---------------------------------------GFPGRAGKKG Caeel HIDEMFKARLHYGHWALYGERLGVCLFDLDI-TKKYLVRALNFVAHVSLRGGMILFVTSNDVEKAADEGTLTNPDAVCFLSTLTSAIVEAIPTIGVVDSNSDPAYLTYLVPANDDTPQSTEYLLRMFKEAVRKG Canalb1 TIAKLMAAGCHLGHPFIYGIYDKVHIIDLNK-TLEKLTLACKVIEGVVEKGGVVLYVGTHALVKASERGTITNPDLMVLLNPVENCIKECIPTIGLCDTDMEPSLLTYPIPCNDDSVRSVNLMLGIMSKSAESG Cangl SIEKLMAAGVHLGQPFIYGEYNGIHIIDLNQ-TLAYLKRAAQVVEGVAERGGVILFLGTRALEEAAKRGTLTNPDLLVVLNPTENALNEAVPTIGIVDTDSEPSFLTYPIPGNDDSLRSVNLLLGVLAKAGERG Capow TLRQLFDAGVHLGHSYIFGERDGIHIIDLEQ-TIVALRRACRVLKHIAYQNGVILFVGGRLVRETAMSGTLTNPDLIVLTCMPMSVAREAVPTIGIADTDCDPRQVTYSIPANDDSPRSMALLLNVMRMAIEEG Catan2 TTQDLIAATTHIGHAYLLGTRQGLHIIDPNA-TLAHLRRAAAFARLVAANGGIVLFVANDLAVEAAEYGTLTNPDLVVAVDLTSKAIKEAIPTMAVVDSDVDPRWVTYPIPGNDDSVHSLELVVKTVAQAVRQG Cioin TMKKLFFSRVYFGHPYLYGNRLGVDIFDLDQ-TLEHMHRALNFVAHIAYLKGIILFIMRSAVELAAKAGLLLNPDICIFLSLQDVAVAECIATVGIVDSNVNPTMITYPVPGNDDSPESVGLYLQLFQLAIQSG CocheC53 TLELLLASEAHQGHRYIHGIRQGVHIISLEV-TAAHLRRSAKVVQEVARRGGMILFVGTRAVARAAELGSITNPDLVVCLNPLENLLHECIPTIGVIDTNADPTWVTYPIPANDDSLRCIQVIAGVLGRAGEAG Coere1 TLEAMMAAGMHLGHPFIFGERQGIHIINLEH-TMAALRRAAAFVRNVAYNGGIIVFAGKRMAIDAALLGTLTNPDLVIVLSPLESMLMETVPTVGVVDTNCDPRLVTYPIPCNDDSLRGMRIVTGVLARAARAG Conco1 TMAQMLESGLHLGAPYIYGTRAGISVFNLEL-TLAHLKRACGVVKEVSRKGGLILFLSHQSTIEAAKRGTITNPDLLVVMNYSSSAIAEAIPTISIIDSDQDPTGVTYPIPGNDDSLRALKLVLGVLSKAGEEG Conpu1 TLSALIAAGAHLGHPYAYGVRADITIIDLDQ-TLPLLRRAASLTRAIAARDGTIVFVGTRAVVKAAERGTLTNPDLVIFLNPLANAIRECVPTIGIVDSNVDPRIVMYPIPANDESTRTAELITGMLSIAGKEG Copci TISALLAAGAHFGHPYAYGTRAGITIIDLDS-TLPLLRRAANVTRAVARAGGQILFIGTRIVQKAAERGTLTNPDLAIILNPVQNAIREFVPTIGIIDSNVDPRLVMYPIPANDENTRAAELIGGVLSIAAREG Croqu1 TLSTLIAATAHLGHPLIYGTRSDLAVLDLRQ-TLTYLHRACNVIRETVENDGIVLFATGIAIKAASERGTLTNPALIVVLSPRDSLLREAIPTIGVIDSDVDPRVVTYPIPANDDSIRLIELLAGVLARAGQEG CryneH991 TLSTLLASGAALGHPYIYGKRAGLSIIDLDQ-TLPILRRTAALVKDIVKADGIVLIVGTRMIQKAKERGLLTNPDLVIFLNASENAIRECIPTVGIVDTDTDPRLVTYPIPANMESMRTAELIISTLSIAGQEG Crypa2 TLELLMAAQCHMGHRYIYGVRSGIHIISLEE-IAASLRRAARVVEEVAYLGGLMLFVGNRVTARAAELGTITNPELVVVLNPLENLLHECIPTIGLIDTNADPTQVTYAIPGNDDSLRSVSVIAGVLGRAGERG Debha1 TISTLMAAGCHLGHPYIYGEYNGIHLIDLNE-TLSALNRATQVIKGVAAKGGVILYVGTTALEEAAKRGTITNPDLIVLLNPVENCINECIPTIGLCDTDMEPSLLTYPIPCNDDSMRASSLMTGILSKSAEEG Dekbr2 SLEKMLACGVHLGHPFLYGEYDGIHIIDLNQ-TLAHLKRAAAAVRGVAQNGGLVLFLGLKAVREAARRGTITNPDLIVMLNPLESAVKEAIPTVGIVDTNCDPGIVTYPIPANDDSVRSTNLICGVLGRAGEAG Dicdi NINYVYKTEFHLGESFIYKEISQIHIIRIPA-FLLIIGKVLNLIREVMRFRGKVVIVANNVIERLVKTKGLTNPAYIVILDAIQGLINESIPTIGCGDTTINFPKLNYPLIGNFKSREKRGSVLLLIKHAMFEG Dmel TVRDLFNARVHYGHPYLFGSRLGHLIFDLDK-TASHLRDALNFAAHIAFRDGIILFFNRNLVERKAQEGIFTNPDLCIFLNTQNNAVRDAIPTIGIVDSNCNPNLITYPVPGNDDSPAAVELYCNLFKEAILRG Enthi -------------------------------------------------------------------------------------------------------------------------------------- Falba NLNTLFRLKAHRGLPYVLGTRKNRTIFNLDY-TLLNLRRALSFIEEVSRLNGQILVVCNNLITKKCREGTLTNPDAVVVFDPNSQLFNECIPVVAFCNSDVNPQQFAYPVPTNDRSHTLVEFYLDSVIQASRTA Fomme1 TLSSLLAAGAHLGHPYAYGTRAGITIIDLDH-TLPMLRRAANLTRAIASQGGTVVFIGTRAVKKASERGTLTNPDLLVVLNPLANAIREAIPTIGIVDSNADPRIVMYAIPANDESTRTAELIAGVLSIAGREG Fusgr1 TLELLLASQTHIGHRYIYGVRQGVHMISLET-TAAHLRRAARVVEEVAYNAGLILFVGNRIVTQAAEMGGITNPDLVVCLNPLENLLYECIPTIGVIDTNADPSWVTYTIPANDDSLRAMAVVGGVLGRAGQRG Galma1 TVSALLAAGAHFGHPYAYGTRSGITIIDLDH-TLPLLRRTANLVRAVARAGGIVVFIGTRVVTKASERGTLSNPDLAIILNPLQNAINECIPTVGIIDSNVDPRLVMYPIPANDENTRTAELIAGVLSIAGREG Ganpr1 SIPALLAANLHIGHPHIYGTRHGVHVINLER-TLQLLRRAAAVVREVAIAGGCIVFVAGRIAVDAARGGIISNPSLLILLSLPPLAALEAVPTIALVDTDADPRLVTYAVPGNDDGAPGVELFAAVLAQSARDG Gloin1 TMSSLLSANLHLGHPFIFGIRYGINIINLDY-TLIYLRRACKVMKEISYNGGIILFINTRSVIKAAKRGTITNPDLLVLLNPLENALEEAIPTIGIVDTDFDPSKVTWPIPANDDSVRGIELLAGILSLAARDG Hisca1 TLNLLLASQTHLGHEYIFGVRQGIHIISLDV-TAAYLRRAAKVVREVARNGGLILFVGTRIVVNAAERGSLTNPDLVVCLNPLENLLHECIPTIGIIDTDANPTHVTYPIPANDDSLRSVAVIAGVLGRAGEDG Klula1 SIEKLMAAGVHLGQPYIYGEYKGIHIIDLNQ-TLSHLKRAAQVVEGVAENGGLILFLGTRTLIKAAERGTLTNPDLLVVLNPTENALKEAVPTIGIIDTDSEPSLVTYPIPANDDSLRSVSLLTSILAKAGERG Lacbi2 TISALLASGAHFGHPYAYGTRAGITIIDLDH-TLPLLRRAVNLVRAVARAGGQILFIGTRVIQKAAERGTLSNPDLAIILNPLSNAISELVPTIGVIDSNVDPRVVMYPIPANDENTRTAELIAGVLSVAGREG Lenti61 TLSALIASGAHFGHPYAYGVRAGITIIDLDH-TLPLLRRAAQVVRGVAAGGGSVVFVGTRAVRLAAERGTLTNPDLVVFLNPIPNAVRECVPTIGIVDSNVDPRVVMYPIPANDESTRTAELIAGLLSVAGREG Malgl1 TLSHLLAATAQMGHPYLYGYRHGMGVIDVERATLPALRRAIQVVRGITENDGIILIIGTRAIRSAIERGVLTNPDLVIVLNPTENALREAIPTMGIIDTNVDPRSVTYAIPANDDSPRVAELVIGLLSKAGEDG Mellp23 TLSTLISASSHLGHPLIYGTRSNISIIDLRQ-TLSYLHRACNVIRETVEKDGIVLFGTGISIKLASQRGTITNPSLIVIFSPHQSLLREAIPTIGIIDSDLDPRLVTYPIPANDDSIRSIELIAGVLSKAGQEG Mnele TLRDLFESRVHLGHKYLYGIRNNMHVIDIAS-TEQHLWRALDVLSHVAYSGGSVLFVNNRIVQEAAASGTFEQPDLVICSSVNNPLLLHAVPSIGILDSDVDPTNLTYVIPGNDDSSQSILLYHRLFAKAVQRA Monbr TIDELFDARVHLGHPYIYTTLADSHIIDLNV-TKAHLEHALELTRRISADGGVVLFVGGRLIRHEARRGTLTNPDLILFFCVPVSGVKEAIPSVGIIDTDGDPDGVTYVVPGNDDTTQAIEFYVRKFADAVLAG Morel2 TIAQLLAAGLHLGHPFVFGVREGISIINLEH-TLTHLRRACTVTKAVARQGGIILFIGTRVTIDAAKSGTITNPDLVIVLNPLENAIKEAIPTIAITDTDVDPRIVSYPIPANDDSVRGVELVAKVLAEAAKEG Mucci2 TISRLMAAGLHLGHPFIFGTREGISIINLEH-TLVYLRRACNVAREVALRGGSILFVGTRLTIEAARYGTLTNPDLIVLLNPLEHAISEAIPIIAITDTDYDPRLVSYPIPANDDSIRGVELVAKVLSTAARDG Mydma DLKKLFDSRVHLGHPYIYGQRSTQLIIDLNQ-TVECLNCALNVLSHIVYNQGIILFISMNLIQKTARDGLFTNPDLVIAFN-NSRAIIEAIPVIGIVDTDCDPRLITYPIPANDDTYDSVSHLCDIFKQAILNA Neucr2 SLEDLMAAQAHMGHRYIYGVRQGIHIISLET-TATHLRRAARVVEEVAYRGGLILFVGTRIVVRAAELGTITNPDLVVCLNPKENLLYECIPTIGIIDTNTNPSWVTYQIPANDDSLRATALISGVLGRAGERG Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------- Pench1 SLEMLLAAGTHLGHRYIFGIREGVHIISLDV-TAAHLRRAAKVVEEVAARGGLILFAGTRAVVQAASLGSLTNPDLVICLNPLENLLHECVPTIGVIDTDADPTRVTYPIPSNDDSLRATCLIAGILGRAGEAG Phybl2 TIAKLLAAGLHLGHPFIFGTREGLSIINLEQ-TLVYLRRACNVAREIAVRGGTILFVGTRLTIDAARQGTLTNPDLIVLLNPLENAISEAIPIIAITDTDYDPRRVTYPIPANDDSIRGVELIAKVISSAAKDG Picst3 SIATLMAAGCHLGHPFIYGEYDGIHLIDLNE-TAAALKRASNVIKGVSKKGGIILYVGTSALEEAAIRGTITNPDLVVILNPVENCINECVPTIGLCDTDMEPSLLTYPIPCNDDSVRSVTFMTGILSKSAEEG Plicr1 SLSALLASGAHLGHPYAYGVRAGITIIDLDH-TLPLLRRAANLVRAVAARDGSVVFVGTRAVEKAAERGTLTNPDLVVILNPLANAIRECVPTIGIVDSNVDPRIVMYPIPANDESTRTAELIAGVLSIAGREG Polpo -------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 TLATLITATTHLGHPLIYGVRSDIAIIDARQ-TLSYLRRACNVIRETVFNDGIVLFSNGVAIKQASERGTLTNPSLIVLFNPRESLLREAIPTIAIIDSDVDPRVVTYPIPANDDSVRSVQLIAGVLSRAGQEG Punst1 -------------------------------------------------------------------------------------------------------------------------------------- Rhior3 TISRLMAAGLHLGHPFIFGSREGISIINLEH-TLVHLRRACNVAREVSLRGGSILFVGTRLTIDAARRGALTNPDLMVLLNPLEHAIAEAIPIIAITDTDYDPRLVTYPIPANDDSIRGVELVAKVISTAAKEG Rhoto1 TASHLVAAGAHLGHPLIYGTRAGLSYIDIRQ-TLPALRRAAQVLKGVVERDGRVVFVGSLAVFENAKRGTISNPDLLVLLSPTLNAIREAVPTIGITDTNLDPRIVTYAIPANDDSPRAVELIAGILGMAGKDG Rozal11 TVQQLMAASAHIGHKFCLGSREGIMIIDLDK-TLFALRRCINVVRETASKRGLILWIGTRLTYECARNGTITNPDLIILLSPGKDALEEAIPTISICDTDTHPIKITYPIPANDDALASVSLIAKSLMYAAIEG Sacce1 TVESLMSAGVHLGQSYIYGEYKGIHIIDLNQ-TLSYLKRAAKVVEGVSESGGIILFLGTRGLEEAAKKGTLTNPDLLVVLNPTENALLEAVPTIAIIDTDSEPSLVTYPIPGNDDSLRSVNFLLGVLARAGQRG Salro SMEDLVQARVHLGHDFIYEKRHGLTVLDLDK-TVPLLQRALDITREIASRGGVILFVSNRMVRRTATSGCLTNPDLVLFFSLPVNALKEVIPCVGLVDTDCDPSSVDYPVPANDDSETSVNLMLDLFAGAVNEG Schco3 TISALLAAGAHFGHPYAYGTRGGITIIDLDH-TLPLLRRATQFARSVAYRGGQILFLGTRVVQKAAERGTLTNPDLVVLLNPIQNAIRELVPTIGIIDSNADPRLVMYPIPANDESTRVAEIIAGVISIAAREG Schpo1 SLPLLLSSGAHLGHPFIYGKREGIHIISLDQ-TMVYLRRAISVVRSIAKENGIILFIGTRSVVAAAKRGLLTNPDLMVILNPLENACLEAVPTIGIIDTDADPRMVTYPIPANDDSLRCTDLIAGLLSRVAEQE Sorma SLEDLMAAQAHMGHRYIYGVRQGIHIISLET-TSIHLRRAARVVEEVAYRGGLILFVGTRIVVRAAEMGTITNPDLVVCLNPKENLLYECIPTIGIIDTNTNPSWVTYQIPANDDSLRATALISGVLGRAGEHG Sphar -MEDLVAAKVHLGHPYLFGVRDDTHIFDLEQ-TMAHLRRALDVVRRVAHAGGIILFIGNRVIRHTAIQGSLTNPDLMIFITLPVSALRESIPSLGIVDSDQDPTQVTYSIPGNDDNIESVELYCKLLKRAVQEG Spipu1 TIRTLMAANLHLGHPYIYGERQGIHIINLEH-TLVMLRRAINVTREIALRGGNIVFIGTRITVEAAKRGTITNPDLLIVLDYPNNAVREAIPVIAICDTDCNPRNVQYPIPANDDALTGVELIAGALSLASREG Sporo1 TTSHLVAAGAHLGHPHVYGTRAGISYIDLRQ-TLPALRRAAQVVKGVVERDGKVLFVGSLAVWDNSKRGTISNPDLLVLLSPTLNALREAIPTIGIIDTDLDPRVVTYAIPANDDSPRAVELIAGVLGMAGKDG Stehi1 -------------------------------------------------------------------------------------------------------------------------------------- Tapde11 GIPALVASQAHLGHPFIYGIRNGIHILNLDL-TLSHLRRAAEVVKGVAQNDGNILFVGTRSVVEAAKRGTITNPDLVIVLNPLENLLKECVPTIGIIDTDVDPRLVTYSIPANDDSIRCTSLLVGVLSRAA--- Thetr -------------------------------------------------------------------------------------------------------------------------------------- Treme1 TLSTLLASGAALGHPYIYGTRSNLSIIDLDQ-TLPILRRTAAMVRDVVRSDGIVLFVGTKIIRKSVERGVLTNPDLVFFLNPSENGIKECVPTIGIVDTDTDPRIVTYPIPANMESLRTAELIAGTLSLAGQEG Trire2 TLELLMASQTHMGHRYIYGVRQGIHIISLET-TAAHLRRAARVVEEVAYRGGIILFVGTRIVTKASELGAITNPDLVVCLNPLENLLYECIPTIGVIDTNADPSWVTYTIPANDDSLRSMALVAGVLGRAGEAG Umbra1 TISKLLAAGLHLGHPFIFGTRAGISIINLEH-TLVYLRRACNVVREVAQRGGTVLFVGTRLTIDAARTGTLTNPDIMILFNPLENAIAEAIPTIAITDSDYDPRRVTYPIPANDDSIRGVELVAKVLAASAREG Ustma22 TLSHLVASTAQVGHPYIYGQRHGVAIFDLERATLPALRRAASVVKAVAERDGVILFVGTRAVLAATKRGVITNPDLVIVLNPIENAIREAIPTIAITDSDVDPRCVTYPIPANDDSIRSVELIIGVLSKAGEDG Walse1 VVNALAAAGAHLGHPYIYGTRHGQSIIDLEQ-TAIAIRRAAAVVKGVVERDGIVLFVGGKATERAAERGTLTNPDLVIFSSPMVYALRECVPTIGLIDTDGDPRGVTYAIPANDDSERAGELIINLLAEAGREG Zygro1 SVNKLLEAGVHLGQPFIYGEYKGIHLIDLNK-TLSSLKRAAKVVEGISERGGVILYVGTRALEEAAKRGTLTNPDLIVVLNPTENALRESVPTIGIIDTDSEPSMVTYPIPGNDDSLRSVNLILGVLSRAGQRG [Cluster2397.fasta_al_trimmed; alignment length = 125] Allma1 -----GTRLSAHN-GQVLVSTGIASLDDLLGGGQPLGTV-LVLDEDIGTGYATLAMQYSLAQALSHGHEAMKIAWRYYC-GVFDLTKRMFLIRLKAASAIITISDFSLAFAGLVAVSLAFHVRRK Ashgo11 MSFRKGLRPSPAT-SHPTTSTGCADMDRLL-GGLPMGQMLLV-EEQGGTDFASVLGKLFAAQGAAHNRQDLRIAWRYYR-HQFDITSRMLLHGVRSCVLLATISDAAICLHGLVHVEWAFKNGRK Aspfu1 MSFRKGIRPSPDD-GRPTTSTGTRSLDNLLAGGLPIGKILLI-EENGTTDFAGALLRYYAAEGVVQDQERMKIAWRYFC-HAFDLTKRLFLHALRAITAMITVPDGVIELQGMLKTDWAFTLSRR Aurde31 ---------------------------------MPSGSIFVALTPDAHSSYGDLLQKYFIAQGLHSGQEKMTIAWRY---NLFDLSTRIFVHALRGSTATITLPDACISFHGLLRVNLAFKTTRK Batde5 SSFRK-TRVSAHN-GQTLTSTGIPSLDDTFGGGLPLGSLLLI-KEDRFTGYAMLALKYYMAQGIASNHDQLDIAWRYYC-RVFDLTKRIFLHSLKSAVCVVTVPDAVIEIHGLIHPSLAFKVRRK Botbo1 SAFKRGTRQNLSTPSILELSTGIPSFDDILGGGLPLGCVLLVLTPDPHAAWGDLVQKYFIAQGLAGGQTKVKIAWRYYC-HTFDLNKTIFLYSLRVAAALVTLPDGCISLHGSLQVNLAFRCTRK Botci1 MAFRKGIRPSPLD-GRPTTSTGIRSLDSILAGGLALGTSLLL-EESGTTDFGGTLLKYYAAEGVLQGHDKMKIAWRYFC-HDFDLSKRLFLHALRALTLMLTLPDGVLEIQGMLKIDLAFSLSRR Caeel CSTKK----------LLETSSGCDSFDTLIGGALVNSSIVLI-DEYRSRCYGSYLIRSFLAEGLHHGHNSMKIAWRY---NQYDFTKHVFLCCLRSMIVYITANDTHIQLHGYFHLDLIFEASSR Canalb1 MSFRKGVRPSLVT-SQPTTSTGSSDLDKIL-LGLPLGNSLLI-EESGTTDFSSVLLRAFASQGILHNRPNLKIAWRYYN-NQFDLTQKLFIHSLRSLVLVCSISDAIIHLQGLVNIEYAFKNGRK Cangl MSFRKGIRPSPAS-SQPATSTGCFDLDKVL-GGLPLGTSLLI-EERNFTEFNSVLVKLMCSQGIIHNRKDLKIAWKYYN-HQFDITSRLLMHGLRGCVLMGTISDSVLNLQGLLHIELAFKNGRK Capow SAFKRGTRPSIHN-GQLLVSTGVQSLDGLLGGGLAVGTLALV-EEDANTAYAQVLLKYFLAEGVAAGHSSLKIAWRYFG-HEFDMSAKVTLFAIRAAVCVVTLPDTVVGLHGLFRIDLVFKLRRR Catan2 ------------------------------------------------------MLGYFVSQGLLHGHDKMTIAWRYYC-GEFDITKKLFLHKLKAASAMITWSDFAVGL---------IRCCRQ Cioin TTFTKGTHPSLHN-GLLLVSTGIPSLDVVLGGGLPVGSIMMV-EEDLFGRFSKIILKYYLAEGVMCNH-DMKIAFRYYG-HYYDISRTMFLHALRAMTCVVTVPDCSIELHGLIRLDLGFELKKT CocheC53 MAFRKGVRPSPID-GRPTTSTGTPSLDGILAGGLALGHSILI-GESGTTDYAGALLRFYAAEGVVQGHEKMKIAWRYFC-HTFDLAKRLFLHALRGLTAIITLPDGVFELQGMFAVDMAFTLSRR Coere1 SSFRKATRLNPHS-AQLLVSTGVPSLDDVLGGGLPVGGILLI-EEDRQTDYSSTLLSYFASQAIAAGHESMKIAWRYFC-ERFDLSLRIFLHRLRGAVCVVSFPDAVIELHGFLHINLAFRLRRK Conco1 SSFKKGSKLSTQN-GQLLISSGISSLDEVLGGGLPVGSLNLV-LEDQFTNYSSYLLKYFLTQGVSNSQDDLKIAWRYFC-NRFDLTNSIFLTQLKGATLMVTLPDSVISLHGFFRLNFVFKLSRK Conpu1 SSFKRGTRLSPSS-ASVITSTGIASLDDILGGGLPLQCLFTVLAPDNHSAYGELVQKYFIAQGLAAGHDKIRIAWRYYC-ATFDLSCRIFLSRLRSACASLSLADAAITMHGFVQINLAFKCTRK Copci SSFKRGTRVSPASSSTINVSTGISSLDDILGGGLPLSCSLVVAAPDLHSSYGELVQKYFIAEGLATGQGKVKIAWRYYC-HIFDLTSRVFLNQLRRACASTTLSDGFLSMHGMVRLNLAFKCTRK Croqu1 STFKKGFYPSHYN-GLPLTSTGIASLDDVLGGGIPASSSFLV-AEDSDSSYARLVLRYWIAQGLAAGQKRMKIAWRYQC-HSFDLSKTLFLLGLKSAACMVTFPDGCLVLQGVCHFNLGFKVGRR CryneH991 -------------------------MDDLLGGGLPLHSILLVLAPDTQSAWGRLVERYWIAQGLASGQER-KIAWRY---SNLSLMTTIFIHSVREASALITLPDACVELHGLLTLNLGFRLKRK Crypa2 MSFRKGLRPSPLD-GRVTTSTGTASLDSILAGGLPLGSSLLI-EEHGTTDFSGTLLKYYAAEGLVQGHEKMKIAWRYFC-HAFDLTKRLFLHALRSLTALITLPDGVLEMQGILRVDLSFHMSST Debha1 MSFRKSVRPSSIT-SQPTVSTGGSDLDKIL-LGIPLGTSLVI-EESGSTDFASVILRSFSSQGVIHNRKDMKIAWRYYN-NQFDITQKLFVHSLRSLVLICSLPDSVIHLQGLVNIEYAFKNGRK Dekbr2 -----GIRPSIVT-SLPCTSTGSEDIDRIL-EGIPLGNSFLV-EEDGATDFGISLLRLFLAQGVVYSRSQMKIAWRYYC-SQFDITSTLFLYGMKRVVLMATVGDAVIELHGHLNIELCFKNGRK Dicdi TTFTRGCKISIKN-SNLLTSTGLTDLDDIIGGGIPIGSILMI-EEDINSSYYMFLLKYFLAEGVLQQQDELKIAWRYFC-HSYDFTRKMFLHALKGATCVISVPDTVVSILGLFNITFVFKMKRR Dmel ----------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------- Fomme1 SSFKRGTKPSPALSSLLLTSSGIPSFDDILGGGVQLGTNFLVLNPDPHSAHTDLLQKYFISQGLSSDQGKVKIAWRYYC-RPVDLSCRIFLLRLRAISAFITLPDACITLHGLLRINLSFKCTRK Fusgr1 MSFRKGTRPSPLD-GRLTTSTGTQSLDQLLSGGMPMGTSLLV-EETGTTDFGGVLLRYYAAEGLVQGHDKMKIAWRYFC-HTFDLTKRLFLHDLRAVTAVVTIPDGVLELQGLLRANLSFRLSSS Galma1 SSFKRGTRISPASNQSLITSTGISSLDDILGGGIPLSCSLVVAAPDIHSSYGELVEKYFVAQGLASGHQKVKIAWRYYC-APFELSSRVFLHSLRAGCASVSLADGAMRVHGLVSLNLAFKCTRK Ganpr1 SSFRRGVKRSPA--GIGVLSTGT-EIDSLLGGGVPLGSVSLL-LEDRLTSYTDIICGCFIAEGVVGESEEMTIAWRY---VTFDFGKKMFLHSLRVASAIVTMPDGVIELHGLVLPNLAFRLRRK Gloin1 ----------------------------ILGGGIPIGSVLLI-KEDRHTEYAKLLLKYFLVQGIVSENEKMIIAWRYFC-STFDLTKSIFLHTLRGGAAVITIPDAVVEVHGLFHVNLGFKLRRK Hisca1 MSFRKGLRASPVD-GRQTTSTGTPSLDNLLAGGFVLGNSLLI-EESGTTDFAGALLRYFAAEGVVQEHERMKIAWRYFC-HTFDLTKRLFLHSMRAATAMITLPDGVIELQGLLKIDWAFTLSRR Klula1 MSFRKGIRPSPAT-SQQTTSTGCTDLDKLM-GGFPLGCSLLI-EEESTTDFNSILTKVYASQGIVHNRKDLKIAWRYYN-HQFDITSTLLLHGLRSCVMLSTISDGVIVLHGLVHIEWAFKNGRK Lacbi2 SSFKRGTRTSPASSSVTTISTGIPSLDDVLGGGLPLSCCLLVTAPDLHSSYGELIQKYFLAEGLACRHRKVKIAWRYYG-HPFELSIRAFLHSLKSGCASVGLSDAALSLHGLVQINLAFKCTRK Lenti61 SAFKRGTRPSPGSPATTITSSGIPSLDDILGGGLPLSCSLLTLAPDAHSAYGELVVKYFAAQGLSCGQTKIKIAWRYFC-RTFDLTYRIFLHSLRAACAAVCMPDASITLHGLVHVNLAFKCMRK Malgl1 SAFRRGVRSAPYDAPVPLLSTGIPALDDIMCGGGILAGSMLAFVPCASTAYTDLFLGYVTAEGLASHHQRMKIAWRY---HVFDLSRRIFLLRLRSTLVSLSLSDGCIGLMGAVRVNLAFKIKRK Mellp23 SSFKKGFYPSHYN-GLPLTSTGIASLDDVLGGGIPASSSFLV-AEDSDSSYSRLVLRYWITQGLAAGQKQMKIAWRYQC-HSFDLSKTMFLVRLKSSVAMITFPDGCLALQGVCHFNLGFKVGRR Mnele AGFRKGTRLSLHS-ALQQTSTGIQSLDLLLGNGINLASSILF-QELDRGEYSPVFARHFMSEGVTHGHDNLKIAWRYFS-HSYDLSQQRFHYNLRKVVTLCIYPNYVLGVHGILHIDRFFKVQRK Monbr SGFVKATRPSKTH-ADPRVSTGIASFDYLLDGGLPLGSLTMI-EQDNTKAFARSMLKYFTAEAVASGHHDMKIAFRYYC-HTFDLGKPMFLHVLRSLTFILGNPDHVAEIQTFIKLDVVLCLTSR Morel2 SSFKKGCRLSAYN-GQVLISTGVPSLDDILGGGLPLGTILLI-QEDRQTSYGQLLLKYFLRQGIVAGDDRLTIAWRYFC-EQFDLTTRIFLHALRGGAAVITIPDASVRIHGLFHVNLGFKVRRK Mucci2 MSFKKGSRLSAYN-GQLLISTGVPSLDDILGGGQPVGTVMLI-KEDRATTYAQLLLKYFIAQGISSGHDRMKIAWRYYC-SQFDLTKRVFFHALRGGTAVVTVPDAVIEIHGFFHVDLGFKLRRK Mydma TSFVKGTKASLHN-SQLLISTGVPSLDTFIGGGLAVGTLILV------GKF-----------------SDLLIAWRYFG-HYFDLSKKIFLLALRSATCMITIPDTVIQINGLLHVDLAFKLKRK Neucr2 MSFVKGLRPSPTD-GRLTTSTGTASLDQLLAGGLPLGTCLLV-EEQGTTDFSGILLRYYAAEGLVQGHEKMKIAWRYFC-HSFDLSKRLFLHGLRALTAIITFPDGVVELQGMFKVNLSFSLSAS Orpsp11 MIIKI-----------------------LLGGGVPMGSLTMI-KKDRYTTYADLFGKYFVSQGLVSNQNELKIAWRY------------------------------------------------ Pench1 MSFRKGIRPSPDD-GRPTTSTGTRSLDNLLAGGLPMGKILLV-EENGTTDFAGALLRYYAAEGVIQEQDRMKIAWRYFC-HAFDLTKRLFFHALKAVTAMITVPDGVIELQGMLKTDWAFVLSRR Phybl2 MSFRKGSRLSAYN-GQLLISTGVPSLDDILGGGLPVGTVLLI-KEDRATTYAQLLLKYFMAQGIASGHDRMKIAWRYFC-SMFDLTKRIFLHGLRGGAAVVTVPDAVIEIHGFFHVDLAFKLRRK Picst3 MSFRKSVRPSLIS-SQPTVSTGTGDLDKLL-LGLPLGHSLLV-EESGTTDFASVILRAFVSQGIMHNRNDLKIAWRYYI-NQFDITQKLFVHSLRAVVLVASLSDSCIHLQGLVNIEYAFKNGRK Plicr1 SSFKRGTRVSPSSASTLITSTGIPSLDDILGGGLPLTCSLLVLAPDSHSAYGELVQKYFVAQGLVSGQDKIKIAWRYYC-RTFDLTSRIFLHSLRAVCVSTSLADAAITLHGLLTINLAFKCMRK Polpo TTFTRGCKLSIQN-GNLLTSTGLNDLDEIMGGGIPVGSILMI-EEDVNSSYYMFLLKYFLAEGVVQNHSDLKIAWRYYC-HSYDFTRKMFLHALKGAVAVVTVPDNVVAILGLFNINYVFKMKRR Pucgr2 SSFKRGFHPSHYN-GVPTASTGIASLDDLLGGGLPISSSFLI-DEDEDGGYGKLILRYSIAQGIVSKQQRMKIAWRYRC-HVFNLSKTMFLKELEMKIAMISFPSGSLSLQGAVHFNLGFKLGRR Punst1 SSFKRGTKASPASTATLITSTGVPSLDDILGGGLPLSCSLLVLAPDVHSAYGELVCKYFVAQGLVAGQTKIKIAWRYFC-ATFDLTQRVFLHRLRAACAVLGVPDGCISFHGLVHVNLAFKCMRK Rhior3 MSFKKGSRLSAYN-GQLLISTGVPSLDDILGGGQPVGTIMLI-KEDRATTYAQLLLKYFIAQGIASGHDRMKIAWRYYC-SQFDLTRRIFFHALRGGTAMITIPDAVIEIHGFFHVDLGFKLRRK Rhoto1 SSFKRGTRPSPYN-AAPLLSTGLTSIDDLLGGGLPLSTSLLI-ESDSPTSYAELLLKYWVAQGLECRQEQMKIAFRYYC-SVFDLTQTRFVHRLRHASCILTFPDGVLRLAGLISFLVGFRVKRR Rozal11 SAFKRGTKLSTRN-SQLITSSGIESVDYVLGGGYPVGTLTTIFSD--HSDYASLMSRYFISQGSINNHEKMKIAWRY------------FMMKLKISICVIVFPDCVMKLQGYFRLELVFKCRRK Sacce1 MSFRKGVRPSPAT-SQPTTSTGSADLDSIL-GGLPLGNSVLV-EEQSTTEFHSILGKLFAAQGIVHNRKDLKIAWKYYN-HQFDITTRLLMHGVRSVVLFASISDSVINLHGLVHIEWAFKNGRK Salro SSFRRATKPSLAN-GQLLTSTGMDAIDHLLGGGVAVGSVFLI-EAQAKSPYADVVLKYFLSQGICHNHKDMKIAWRYFC-HTFNLSQQVFLHQLRGAVVFVTVPDAVVRMHGFFKVDLVFKLKKK Schco3 SSFKRGTRPYPGSPSTIVTSTGIPSFDDILGGGLPLSCSSLIAAPDVHSSYGELASKYFVSQGLVHGHDKIKIAWRYFCEAAFDLTSTVFLHSLRGACASICLADAALSLHGLVTINLAFKCTRK Schpo1 MSFKRGVRLSSKD-ARWITSSGSSSFDYYLSGGIPMKSLLVI-EED-SMDYASVLLKFFAAEGLKQDHERMKIAWRYYT-HSFDLSKNLFIHTLSSLICMCSVPSAVFSLLGLFRIDLSFTVSKR Sorma MSFVKGLRPSPTD-GRLTTSTGTASLDQLLAGGLPLGTCLLV-EEQGTTDFSGILLRYYAAEGLVQGHEKMKIAWRYFC-HSFDLSKRLFLHGLRALTAIITFPDGVVELQGMFKVNLSFSLSAS Sphar ----------------------------------------------------------------------------------------------------------------------------- Spipu1 SSFKRGVRLSPHT-GTHQTSTGIPSLDSLLAGGLPLGTVTLL-QEDQFTRYARLIASYFVAQGIVAGHDRMRIAWRYYC-AIFDLTKRMFLHTLRPAVCLITLPDGVLSLNGFLDVALGFRVRRK Sporo1 --------------------------------------------------------------------EKMKIAFRYYC-STFDLTTTRFLHRLRSASSLTTFPDSVLSLQGLLTLLLGFRVKRR Stehi1 SSFKRSLRPSPTSSSTLLTSTGLPSLDDILGGGLPLSCSFLVLAPDVHSAYGELVCKYAVSMGLAGGMSKIKIAWRYFC-RTFDLTNRIFLHTLRHACATISLSDGCVCFHGLLRINLAFRCLRK Tapde11 MSFRKGVRPSAAN-GVPVTSSGCMSLDTVLSGGMPVGSGLVI-EENGTTDFSSVLLRYFAVEGLLQGQERMKIAWRYYC-HAYDLTKRMFANNLRALLVMMSMPDGIIELQGLLKIDLSFKVTRK Thetr ----------------------------------------------------------------------------------------------------------------------------- Treme1 PSFTRGTHPSPST-SLPLISTGLPALDDLLGGGLPLSSILLVLSPDPHSSWGKLVSRYFLAQGLSTGQERGKIAWRY---NHLSLMHTIFLHSLRSSSAIITLPDACIELHGTFHLNLSFRLKRK Trire2 MSFRKGTRPSPHD-GRLTTSTGTSSLDQLLAGGLPLGTSLLL-EESGTTDFGGILLRYFAAEGLIQGHSKMKIAWRYFC-HTFDLTARLFLHQIRAIVAMMTLPDGVLELQGLFRIDMSFKLSAS Umbra1 MSFKKGSRISAYN-GQLLISTGVPSLDDILGGGLPVGTVLLI-QEDQHTSYAQLLLSYFLAQGVACGHDKMSIAWRYFC-DTFDLTTKIVLHALRGGAAVITVPDAVVEIHGFFHVNLGFKLRRK Ustma22 SSFKRGVKPSSFSSPVPLISTGVPALDDLLSGGGLSSSSDLLLLPATGTAYVELLLGYSIAQGIAAEHRGMKIAWRYFC-HTFDLSRRIFLHRLKRSMAVISISDSAVSMTGAFKVNLAFKVRRK Walse1 SAFKRGTKVSPSN-ASLHLSSGSAAIDDLLGGGIGTNTINLVVETDPHSTYSDILLNYFYSQGLKSSHGESKIAWRYFL-STFDLTQNVFIYKLRSAAAYISTHDSCIALHGLIHPNLAFKLRRR Zygro1 MSFRRGIRPSPAT-SQQTTSTGCQDLDRLL-GGLPLGNSLLV-EEKTTTEFNTVLCKVFAAQGIVHNRNDLRIAWRYYS-NQFDITTRLLVHGLRGCALLATVSDSVLTLHGLLHVEFAFKNGRK [Cluster2398.fasta_al_trimmed; alignment length = 141] Allma1 DDLD-DLLAGVLGDLDDLMRELAANMAALMGFQDRVRRTVDKLQDSDKQADSLMAEMMKFESVLEGMMESLMSKDILHEPLKDLAAKYPAYLEANKALPADEYAKYEKQITEICVIYDIVALMTEVQD-LGQP-PAELLKE Ashgo11 VDEY-D-LDAYLDDGAEMINDLQTQFQQMLRFKDIISNALGRLKVNSSKIDDLLSQLLEMDGAILNILNQMSSKEVMYQPMKEMQLEFVQWMQGNAEEHREKIATYRQQVNAIVALYEITDLIDKLEQ-LGDS-PVNKGFS Aspfu1 DEDS-EDLDDVLDNFDAFMRQLEQDMAKMM-FNDAIQRTINRMKESGDKAEDMLMQLLKLTQMIAGVMEQFSNKEMLYEPMKELDAKWGPWLKENKKVPAEDMKRYEKQVTEIVAKFEVWEKMQEMQA-LGSP-PEELVAN Aurde31 DDDV-D-LDDVLDEFDAFVRDLAAGMENLMRFQASLRATLDKLKNSEDTLDSF-AQLQDLSGVLQGLMQSLMSKDILYEPMKDLSAKYPEYIEQHKTLKADELNRYQEQVGRIVAIFEVLALMNEMQA-LGSP-PQEIMGD Batde5 DDDW-DLLDGVLDEFQEFMAQLAKNMEMLLQFQDHVAQTMNKLRESSDKADPLMADMLKFEDMFGGFVDQLMKKEFLYEPLKTLSEKYPPWLEANRSLTEHDRVRYESQIYEIKSIYEIMDCLAKIQG-FGNP-PDELMKQ Botbo1 DDNL-D-LDDVLDQFDDFAKELAAGMEALMKFQDTIKEAMRKLKRSDDDAAALLDQMGDLQKLLEGMMGELMSKEVLYEPLKELDDKFPEYLAKNDTLSSDDSKRYKSQVKRIVEIFEILHLMNEMQS-LGTP-PPEIMGP Botci1 DED--DDLDDMLDEFDDFAKQLQAGMAELM-FQETIKKTMERMQASGDQADDLLAEMMKFSKMLLGMMEQLTNKEILYEPMKELDDKYPAWLEKNSSVPADDLKRYKEQVREIVARFEIVERMQKMQA-AGSP-PADLVGD Caeel --------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 DDDL-D-LDDLLDDFDPLGNDFQKSINELISFEYVMKETMERLKKSGDDIEDLLTQLLSMSKLLVDMLEQLSSKEVLYEPIKDLNTKFPEYLQQNKKLDEAKYKNYTQQTNDIVRIFEVNSLLESLQE-LGQP-PSELVGE Cangl FD-Y-D-LDDLLDE-KEMIEDLQQEFQNLMKFKDVISSTLDRLKENANKVDEVLSKLLNMDNAILGILNKMSSKEVLYQPMKDMQIEFSKWLEDNKPSHKDNMDTYKRQVNKLIVIYEVTELLDQLEQ-LGDS-PVSKNFN Capow DDQL-DLLDEALEGFSALAAQFQQQLLAMMQFEQAIHE----MQQNSQQLDALAEQLLAMQAMMEKMMETVLNKDVLYQPMKSLSERYPEYLRENAKISAEDKTRYELQMHKIVATFEILELVQEMQE-HGSP-PPEIFAE Catan2 DDID-DLLDDVLAGMDAFARELSAGMEQLMSFQDRIRQTMSKLEESD---DSLMAEMMRFDSVLEGMMESLMAKDILHEPLRDLTDRYPAYLAENKKLPADEYDRYTKQMKQVITIYEVIQLMTEIQE-LGQP-PAELMRE Cioin --------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 EED--DDLDDVLDEFEEFQKQLQKEMEQLL-FQETIKKTMERMQSSSDTADDILAQMLAFSKVLMGMMEQLTNKDILYEPMKELDDKFPKWMEENKKVEKDDLKRYEEQVREIVGRFEIVERMQKMQA-AGSP-PPDLVGD Coere1 DDEL-DLFDNALEEFEEFIRQLTQGMDDMLKFQDKINATMAKLKDSATQADELMRQ---LDTLADDVVGQLMSKDLLQQPLQQLENAYPKYLENNKTLPKKDLQRYEQQVKQILALFKIVELMQKMQD-CGQP-PSELLKL Conco1 EDDL-DLLDDALDDFNEFNEQLAQGMQELLKFSDAINQTMNKLKNSSDQVGDELSEIIKFEKAIESMMGTIMTKDLLYQPMKDLADKYPEWLEKNKELTDVDYERYIKQISKVIVEFDVMELMQEMHE-LGQP-PATLLKE Conpu1 -------------------------MESLMSYQTRLRDAMNKMNASESTLEALLAQLAGMKGMLEMIMGQLMSKDVLYEPLKELSDKFPDYLAKNAALSEADKTRYDAQIKSLLDVFNVMKLMEELQK-HGSP-PEEIMGP Copci EDDL-D-LDDVLDEFSAFARELAKGMEDLMRFQERIRQAMDKLKESEDKAEDLLKGLSDLAGFLESMMSQLMSKEILYEPLKELRDSFPGYLANPPPLSDEDRSRYEKQVTQIIDLFEVIDLMSEMQS-HGSP-PTELMGD Croqu1 EDDM-D-FDDILEQFDDFARDLAEGMEALLSFQDAIRSTMEKLKESDSSAAALFEQMMSLQTMLQGFMEELMSKEVMYEPLKEMNQQFPGWLDENRKLSKEDLDRYQTQVSKVVKKFEVVILLTKMQD-CGPP-PQEIMGE CryneH991 EEEE-DDLDNVLESFEDFEASLMQGMESLLRYEDTLRKTLESLKSAGQNSASLFASLGGFEGILEGMMAQLMTKEVLEEPMSELAVKYPAYLKSPPDTSPEDIAKYHQQVTQIVETFKIARLVSEMQD-LGGP-PKEVMGD Crypa2 --------------------------------------------------------------------------------MKELNDKFPDWMDKNRKISEADRKRYEEQVKEIVAKFEIVERMQKMQA-AGSP-PPDLVGD Debha1 EDDL-D-LDDLLDDF-PLNDEFKTRIEDLVKFDNVMKETMERLKKSGDTIEDMLTQLLAMSKLLVDMLEQLSSREVLCEPIKDLHSKFPDYLKEKKKISEEEHANYTKQSGEILAIFEVNSLLESLQE-LGQP-PTELVGD Dekbr2 DDDL-D-LDDLLDDFGNGVEKGEKGFEALLNFQEAISETVHRSKRSGSQVDNMLETLMKINSLLAEMLDQLSSKSVLYEPLNDLYLKFGPWLQDPAKLDPE-YSKYQKQVKALVLRFQINDNLESLQE-LGSP-PKELMND Dicdi --------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------- Enthi NQSIGD-------------------------YYDLINQ-INQIDKSSDDK---------VEETLISMLRPFLSKDILYEPIKELKEQYPEWLEKNKIITSEEFEKRIKQVCKIVELFEIVELIQKM----GQP-PHGLV-- Falba -----DCLSFPSSYF------------AALSLEDAIRQSAKEHSQAHDALDDMFASFSDMTNFLEAMMVQIVSREVLYEPILMLENNYPIWLAANRTLSPEEQSVCDQHLRKILLTYNLLQYIQDIQA-VGAI-PVGFLNE Fomme1 EEDV-D-LDDIVDQFDELAKDLADGMEALMRFQASILQAMEKLKDSDSTLEAILNQLG-LQDMLETMMQQLMSKEVLYEPLKELHDKFPGYLSENDKLSTEDKERFRNQVSAIMQIFEIVSLMNEMQS-FGSP-PSEIMGS Fusgr1 DED--DDLDDMLDEFEEFAKQLQAGMADLL-FQDTIKRTMERMQASGDQADDFMSEMLKFSKMLMGMMEQLTNKEILYEPMKELDEKFPEWLIKNRATPKEDLKRYEEQVRQIVAKFEIVDKMQKMQA-AGSP-PSDLVGD Galma1 EDDL-D-LDDVLSEFSEFAKELARGMESLMRFQDKIKQAMHKLKESESKLEALLKSLGDLAGFLENTMGQLMSKEVLYEPLKELADGFPPYLEKPPPISAEDRTRYDSQVRKILAVFEIVDLMSEMQS-YGTP-PAEIMGP Ganpr1 DDDL-DLLDDVLDDFDDLSLQLAKGMEALLAFQDAIAATMERMKEGKEEM---LAGLLS----LERMMEQMLSKEVMYEPMKEMGREYPPYLERHKPPDPAEYALAEQQILEIVRIYEVTELMQKMQE-LGNP-PAEIVRA Gloin1 TDDL-DLLDEALDDYDEYVKLLTADMEDFVKFQDKINQTMNKLQNSSEQLNDQIMEMMKMEKMLESMMEALATKDYLYEPMKEFAQKYPKWLEDNKKVPPEDYARYEKQINKIIEKYDIINLMQELQE-FGQP-PPEILNE Hisca1 DEE--DDLDDLLDDFDAFLRQLEHGMAGLLHFQQTIRKTMERIQASGDKADDVLMRLLKLDKLFMGIMEQLSNKDMLYEPMKELNDKFSPWLRENRKVPKEDLERYELQVAEIVAKFDIWEKMQKMQA-AGSP-PDALVSN Klula1 VDEF-D-LDDYLED-VEMMEDLQKQFQQLMQFKNIISNTLDRLKENSTKVDDILSQLLDMDNAILKMLSQMSSKEVLYQPMKQMQGEFTEWMGLHEPEHSDKIDNYKKQVNQIIGVFEIADLLDELEQ-LGDS-PVAKGTS Lacbi2 DEDV-D-LDDVLSQFSEFAKELSMGMESLMQFQDKIKQAMDKLKESETNLEALLKSLGDLAGFLETMMGQLMSKEVLYEPLKELAEGFPPYLTNPPPLSPEDRSRYEKQVKRILAVFDIVDLMSEMQS-YGSP-PAEIMGP Lenti61 DEDL-D-LDDVLEQF--FARELTKGMESLFRFQENIKRAMDKLKESD---EDIFSRL--LKGILETMMSQLMSKDVLYEPLKELHDKFPSYMKDNDTLSAEDKTRYVSQVAQIVATFEVVELMQEMQE-YGSP-PAEIMGP Malgl1 LDDL-DQLIDVLDDFDEFVEELTKNMESFMAFQDAVKATMDKLKQSNASANADFSKILELSKMLAQMMEDLMNKDVLYEPLKDMHSRFPAYLASPAKLDDDTRQAYVAQMGEIIAVFEVADLVSKLQE-FGTP-PQELLGD Mellp23 EDDM-D-FDDVLDQFDDFARDLAEGMEALLSFQDAIKNTMDKLKESDVSAAALFEQMMSLQTMLQGFMEELMSKQIMYEPLKEMNRQYPGWLNERKTLPKEDVDRYQTQVAAVVNKFEVVNLLTKMQD-CGSP-PQELLGE Mnele --------------------------------------------------------------------------------------------------------------------------------------------- Monbr DDDF-NLLSDVLEDYDALADQLADDFLRDLQEPDSFASLLQDLNAASSADDHLVQSLLS----VAGMFNALVSKDVLYPSIQELCDKYPEWLATRGDLEAKDRGRYEHQLCRARVIFDVFVVLTQMAE-TGPP-PRDLVEE Morel2 ---------------AEFSKQLASGMEELMKFQDRIAKTMDKLKDSSEQVEALMAEMMKFQNVLEGMMEQLMSKDILYEPMLDLQNKYPQWLKDNKKISAEEYARYEKQVKEIVEFFDVIDLMQGMQD-CGQP-PADILDE Mucci2 DSDI-DLLDDVLDDMDDFAKQLAAGMEQLMGFQDTIGKTMNKLKDSSKEIDAFMAELMKFEGVLEGMMSQLMSKELLYEPMKDLAQKYPAWLEEHKTADKADYEKYKQQCQQIVAKYEIMDLMTKMQD-LGQP-PAELLDE Mydma EDDI-DLLDDALKDFDDGMFDVVGSIQEALEFDDNIAKTMEELTKSFHEMEEIFRQVKTFMNMMQGMMQNLLSKELLYPSLKEIKEK------------------------------------------------------ Neucr2 DED--DDLDDMLDEFEEFAKQLQAGMADLL-FQETIRRTMERMQTSGEQADDFLAELLKFSKMLMGMMEQLTHKDILYEPMKELHEKFPGWLEKNRTTSKEDLERYELQVSEIVAKFEIVDRMQKMQD-AGQP-PNDLVGD Orpsp11 DDDL-DFLDGVLDNFAEMAKQLTQGMFQLLQFQDTISETINNLKNSSDKVNDVMEKLLKFCDILSGVIDQLMSKELLYDSMKDLSDRYPSWIEENKKLSKKDIENYQGQCKEIVDIFEVSELMQKMQG-FGNP-PAEILKE Pench1 DEDS-DELDDVLDDFDAFLKQLEQDMANMM-FNDAIKRTMGRMKESGDKAEDMLAQLLKLSKMFMGMMEQLSNKEMLYEPMKELDVKFGPWIEKNKKVSAEDMERFETQVKQIVEKFEVWERMQEMQA-AGSP-PEELVSN Phybl2 DSDF-DMLDDVLDDFDEFSRQLAAGMEELMGFQDTIAQTMNKLKDSSKQVDAFMAELMKFENVLEGMMQQLMSKEMLYEPIRDLAKKYPSWLEENKKLNKTDYEKYSSQCQQIVAKYEIMDLMQKMQD-FGQP-PPALLEE Picst3 DDDL-D-LDDLLDDF-PLNDEFKLNIEGLIKFEYVMKETMERLKKSGETVEDMLSELLAMSKLLSDMLEQLSSKEVLYEPIKDLNTKLPGYLKENKVINEVQYAKYSSQTGEILAVFDVNSLLESLQE-FGQP-PVELVGE Plicr1 DDNE-D-LDDVLEQF--FAQELARGMESLMRFARTVRSTLDKLKSSESA-EALLAQLGDLAGMLESMMGQLMSREVLYEPLKELADKFPGYLKEHATLSTDEKTRYDAQVNAIVGVFDIVTLMNEMQS-FGSP-PSELMGP Polpo --------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 EDDMED-FDDLLDKFDEFARDLAEGMEALLAFQEAIQETMEKLKRSDDSASALFEKMMSLQTILQSFMEELMSKEIMYEPLKDMNRLFPDWIEENRKLSPEDMKRYETQIEQVIERFDVIELLTKMQD-CGPP-PKEILGD Punst1 DDGL-D-----------FARAFAKEMESFMKFQKTIRETMDKMKQSEEALEALLAQL--FQSILESMMTQLMSKDVLYEPLKELHDKFPDYLAENSKLSTADKDRYERQVQQIVEVFEIVTLMNEMQS-HGSP-PPEIMGP Rhior3 DSDI-DLLDDVLDTMDEFAKQLAAGMEDLMGFQEAIGKTMNKLKDSSKEIDAFMAELMKFESVLEGMMSQLMSKELLYEPMKDLAQKYPEWLENNKKVKAEDYDKYRQQCQQIVAVYEVTDLMTKMQD-LGQP-PSELLDE Rhoto1 HDDL-D-LDDVLDEFPQLAKDLEEGMKALLAFQEAIAASMSKLRDSSTSAAG-MAAMLALQDMLDEMMKQLMSRDMLYEPLKELADKYPAYLEQHRTLSAADIERYEKQVRQIVDKFEVVDLVAKMNE-CGAP-PNEIMGE Rozal11 DDDL-DLLDEALEDFQEFLDELSKGMESLLKFQSKIDTMMERLKQSQEEVNNLFENLL-SSGLLDGLLENFLTKDVLYEPMKDLALQYPEWIEKNKKISKEDLSNYEKQVNEIVVAYEVITLLQKMQE-FGTP-PEEMLAD Sacce1 YDNF-D-LDDLLDE-KEMMVDLQNEFANLMKFKNIVSNTLDRLKENGNKVDDILSQLLDMDDAITKILDQMTSKEVLYEPMKEMRSEFGVWFQENGEEHKEKIGTYKRQVDEIVNIYEVTELLDELEQ-LGDS-PIRSANS Salro --------------------------------------------------------------------------------------------------------------------------------------------- Schco3 DEDL-D-LDDVLDQFAEFTKELARGMESLMKFQAKIRQATQKLRESESNMEALLKSL-DLTGFLESMMSSLMSKEVLYEPMKELEEKMPAYLENPSPLQAGDKERYQSQVRKIIATFDIVDLMSEMQD-YGPP-PSAIIGQ Schpo1 FDDL-D-LDDILDDL----------LNSLIQFQN----------------DQLLNVILELEAALNSLMSQVTSKEILYEPLKDLEANYPKFLKNAK---ETEKQGFEEQIQKCIQIFEISKLVEEIQE---KPLPAPLIDN Sorma DED--DDLDDMLDEFEEFAKQLQAGMADLL-FQETIRRTMERMQTSGEQADDFLAELLKFSKMLMGMMEQLTHKDILYEPMKELHEKFPGWLEKNRATSKEDLERYELQVSEIVAKFEIVDRMQKMQD-AGQP-PNDLVGD Sphar --------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 VDDL-DYLDDVLDDFDDFARQLASNMEQLFKFQETIAQTMHKLRDSSDKVEA-MEQMMKFDGMFGGLMDQLMSKELLYEPMKDLATKYPQWLAANEKLSQEEMEKYRRQIVEIVHIYDVADLMQKMQE-CGNP-PDEILQE Sporo1 TEDL-D-LDDVLDQFPAIAKDLEQGMKAFFDFQDAIAASLSKMQSSSSTASGNLASMLALQGMLDEMMKQLMSREMLYEPLKELSGKYPAYLESARTLSPTDLERYEKQVVSIVSKFEVVDLVAKMNE-CGAP-PKEIMGE Stehi1 EEDL-D-LDDVLDQFDAFASEFAKNIESMMKFLKSVRQAQEKLKESEANLEKLIAQLGSFSGILEGMMGSLMSKDILYEPLKELHDKFPPYLSENKKLSTEDNERFVAQITKIVAIFEVMQLMTEMQS-HGSP-PAEIMGA Tapde11 IDDL-D-LDDLLDDFDDFAKQLQNGMEDLMRFQDSIEANLQRMKASESQIDTFMAEMMRFSQVLEGMMSQLMSKEILYEPLLELHQKYPTWIAEHP--KDEKIETYKKQVAKIVAKFEVMDLMSQMQD-LGSP-PAAIMSE Thetr NPDL-DLLENALDDLAAGAAGAGKDMDAVLDLSEEFKGLMEQMPELEKMANELMPDLEKLASMLDALLKPLIHKDLLQEPIREVGNLYPPFLASAEALSAEDRARFEGQFMAIDAAFEVLELLTQLHDKYGAL-PDSIQAS Treme1 DDDD-DGLEDVIASFDDFEAALVEGMESLLRFDETIKRTMENLNAA----GKLLKALQSLGGLLDGMMSQLMTKEVLEEPMAELAGKYPSFLASPPNLSPAEVDKYKRQVTQILAVFRIAKLVGEMQD-LGGP-PSEIMGD Trire2 DED--DDLDELLDGFEEVTKRMQAGIAGLL-FQDTIRRTMERMHASGEQADDFLSEMLKFSKMLMGMMEQLTNKEILYEPMKELHDKFPAWIAKNKSVPADDLKRYMEQVEEIVAKFNIVDRMQKMQA-AGSP-PSDLVGD Umbra1 -------------------------MEELMGFQETIAQTMNKLRDSSDKVDAFMQEMMRFQNMLEGMMSQLMSKELLYEPMKDLAAKYPDWLDKNKTTPKDEYEKYKQQVKQIVAKYEVVDLMQKV--------------G Ustma22 VDNL-D-LDDVLDEFEDFAKELAQGMQALMKFNDAIAATMAKLKESDASAEE-MAKLLALTKMLEGMMDELMSRDILYEPLKELRDKYPAYLAGPESISAEDRKRYEEQITEIVKIFDVQELMNQMQD-CGSP-PKQIVGD Walse1 DDDD-DNLD----------------------------------------------------SILESVMTELLSKDILYEPLKELSTKYPDYLDNNKKLSQEDYDNFKKQVNDVLAIFE----------------------- Zygro1 QD-Y-D-LDDLLDE-KQMIADLEEEFGKLMNFKNVVSKTLERLKENGSKV-DVFTQLLNVDDAILAILNQMSSKQVLYEPMREMHTEFAKWLDANGKTNEEDLQKYHRQVGRVVQVFEVTQLLDQLEQ-LGDT-PVSKAQN [Cluster2402.fasta_al_trimmed; alignment length = 137] Allma1 PLATPPDVIRAAQKDDYLRNSMAEVVAASTLYYALTTGQSTLGEEYCDIPARWRRPAFLQLHLAVFYFGAYYTLAKRIGIRYLSYAPLGRLLLVQILTTGDCVLCMCPRSTAGPCGHLFCWSCVCEWLKEKRDLICV Ashgo11 PFADAPSIVQAHQKDVYLGTKLEDALKSKILYLGLTTERRTLGEEYVDLVKAWRRPYGLSVHLLVFYLGGFYQISKRIGLRYASYRILGGLVLLQLLAKRKCILCLADMPSCLPCGHMFCWACVMQWCNERQSILQL Aspfu1 PFATSPDIIRSNEKDIFLVNQAQAIIRTEILYFSLTTGNRTLGEEYCDLPAIHRRPWALQLSIATFYFGSYYHLSKRFGLRYVGYEVLGVLLVLQIAVQSKCTLCLELYPSVTTCGHVFCWTCIRDWVREKSKVLPL Aurde31 PRATQAQLIRANQRDLMLRDMADSVLRSRLAYLGLTTALQTLGEEYVDIPSTALRQYAASVNLALFYFGTYYTLAKRLGIRHISYALLGVLISVRLIYRRRCVLCLEERSCATECGHLFCWTCIVGWGREKARLQPI Batde5 PFASPPDIIRATQKDLYLQSTLNEIIASQALYYGLTTGTQTLGEEYCDIPSHW-RPYFLHLHLASFYIGTYYHLAKRFGIRYTGYEVLGFLIYIQLIIQQKCTLCLGERTTATPCGHLFCWKCIGDWCRNKNQLYPI Botbo1 SPATQQQIVRANQKDVYLREQTESVLRSRLVYFGTSSGAQTLGEEYVDTPSTRLRAYIRSINLAVFYLGSYYTISNRISIRRLSYSFLGVLISMRLLYKRRCALCLEERSCATECGHLFCWRCAVGWAREKTRLLPI Botci1 ----------------------------------------------------------------------------------------------------------------------------------------- Caeel YVAEIGEIVRSQRRDEEITERLSRVSKASTLYYTSTVGNQTLGEEYVHLPSIPSRNYLIQAHIALFYIGAYYSIARRFGIRFL-YRFLGYITLIQLAVSFQCSICLENKPSALFCGHLFCWTCIQEHAVAARDVTPL Canalb1 PFADAATIVRAHQKDAYYRTQLQELFQAKAVYLSLTTGARTLGEEYVDLPKLLPRPYIISLHVALFYFGEFYSLSKRLGLRYANYSLLGGIIVLQFIVKRSCMLCLSPMPSAANCGHLFCWDCIVDWIREHQHLLPL Cangl PFAGAPSIVQAHQKDEQLSVKVSELLRVKLIYLGLTTSRRTLGEEYVDLVRGIKRPYLVTLHLMVFYIGTYYDVFKRFGMRYASYKILGYIILLQHISKRNCILCLMEMPSCLPCGHVFCWDCITDWTKENQQVLAL Capow MLASQADIVRSSQKDRWLMEELTAAASAELLYLALTTGSKTLGEEYCDISSR-RRPYIVDAHLAFFYFGLYSHITWRTSIRYISYRLLGLLSSVQLLVTSKCSLCLAARPTVTPCGHLFCWKCIAEWCTTKSRLCCI Catan2 PFATPPDMIRAAQKDDAVLAALQSVLAASALYLVFTTGAATLGEEYCDLAKRWQRPAFLAAHLAVFYFGAYYHLARRIGIRSMSYAPLGYMLLGKVAVTGDCVLCMGPRSTVAPCGHIFCWSCVGEWVLEKRDLLCV Cioin MALGSPDVVTSVRKDTQLKGLVNESAHSEFLFYFLTTNLQTLGEEYTGMPSLLRRPYLLNLHFCLFYMGIYYSIPKHLGIKYLNFANLGRLSMLETL--SVCLL-------------------MFNWYKKKLNLIP- CocheC53 PFAASPDIIRSHQKDAYLLEHLSSLLRGELLYLGLTTGNRTLGEEYTDIPALGRRPYVLGVSLATFYFGSYYHLSKRLGLRYIGYEVLGVLLVLQMAVQRKCTLCLEEMPSVTTCGHVFCWTCIGDWAREKQHILPL Coere1 PFAGQPDIVRATQKDLFLRQQMAELIQCSALYHGLTTGSQTLGEEYCGTPSFIRRAFLLSAHLAVFYIGAYYSVAKRLGVRYVGYEILGALLGAQLVVQQKCTLCLSTRSAATPCGHVFCWTCVL------------ Conco1 MI-----------------------------------------------------------HLVIFYFGSYYHLSKRLGIRYIGYEILGILLGIQLLVKGKCALCLSVKPTCTPCGHIFCWECISEWCRTKSQLWTI Conpu1 PAARQAQIIRAHQRDLYLREQAEGVVRVKALYYGMTSAIQTLGEEYTDIPSPLIRSYVLSVNLAIFYLGTYYDLSKRVGVRHLSYSLLGILIAARLIYRRSCTLCLEERSCATECGHLFCWSCIVGWGREKTRLLPI Copci PQAQQAQIIRANQRDIFLKEQVEAVLRIRLIYYGLTTATQTLGEEYTDIPTSLLRPYILAVNLALFYLGSYYDPVKRLGIKNLSYSLLGVMIGARLLYRRSCTLCLEERSSLTECGHLFCWNCIVGWGREK------ Croqu1 PNAAQPEIIRADQKDAYLQDMLESSLRGRLIYYFLTTASQTLGEEYCDIPSIKRRPKILNLHLAIFYLGRYFHWSNRLRIRYLSYEFLGLLMVVQLIVRRRCTLCLGPRQSSLECGHVFCWRCVVGWVREKTDLLPL CryneH991 EPASQAQILRSHQRDTALTELASEITRIKGIYLSLTLGSQTLGEEYTDIPSKTRRPTILVLHMIAFLFGRFFELARRVGMSYISYEPLGLLLLIPFIHRRQCTLCLEPRVAVTECGHVFCWGCLGGL--EKERLTAA Crypa2 PFATAPDIIRAHQKDAYLTNQLLDLHRGDLLYLCLTTGNRTLGEEYCDLPSLRRRPYLLSVVLAAFYFGAYYSLSKRLGLRYVGYEVLGVLLVVQLAVQRKCTLCLEELPAATGCGHVFCWTCIGDWVREKQHILPL Debha1 PFADASTIVRAHQKDTYYRSQVQDVLHAKSLYLMLTTGARTLGEEYVDLPQLLLKPYLFTLHIAIFYFGEFYSLSKRIGLRYADYSLLGGIILLQFFVKRACMLCLSPMPSAASCGHLFCWECIVDWVRDHQNLLPL Dekbr2 PFATAPTIIRANQKDSYLLKQVTDAISVKFIYLGVTTGARTLGEEYVDLPNLIRRPVLLKLHLALFYFGKYYQFSKRFGLRYANYELLGLLIMTQLAIKRNCMLCLSPMPACAPCGHLFCWKCIFDWCKERAQLLPL Dicdi SYADQPDILRSSQKDEYFEDQCFEMLTANTIYYLLTTGSQTLGEEYCNLPSIPDRPYLIKLHLALFYFGSYFEFSKRLDIRYIKYDILGLLIIIQILLSQKCTLCLEVRTTATICGHLFCWHCITEWCNNKRTCVPL Dmel ARARQPEIVRSVQKDARLAEDLSDVLRAELSYHGFASNLQTLGEEYTGIPSRLLQDSLFQLHKSLFYLASKYQLSKRTGINYVGYKILGVITFLQVSVSPQCILCLEPRSSLTPCGHIFCWSCLLEWLEERSQVILL Enthi ----------------------------------------------------------------------------------------------------------------------------------------- Falba AVAGPERVTRYR----PITSSLYHL---SYLAFGSTP-----GEEYADLPGLFRTPHALAFHTALFFLWHYLSLSRRIGYLYTSFRTVGVLKLVEAIVSSPCSLCLSQQPAASTCGHVFCWECIYSWLVENNQLMCV Fomme1 PAAQQAQIIRAHQRDLFLREQAENVLRSKLVYYGLTTAQQTLGEEYTNIPSARKRAYIISINLAVFYFGVYYNLVQRVGVKTISYSLLGILILVRLLHRRSCTLCLEERSCATECGHLFCWSCIIGWGREKTRLIPI Fusgr1 PFATAPDIIRSHQKDAYLAQILSDLHRATLAYFALTTGNRTLGEEYCDLPAIDRRPYIAAVILALFYFGTYYQLSKRLSLRYVGYELLGVLLVVQLAVQRKCTLCLEEMPSATQCGHVFCWECIGDWVREKQHILPL Galma1 PRAQQAQIIRANQRDLYLKDQAENVLRVKLCYYGLTTAIQTLGEEYTDIPSAPARSYILGVNLAVFYLGTYYDLMKRLGTQHLSYSLLGILIMVRLCYRRNCTLCLEERSCATECGHLFCWNCIVGWGREKDKLLPI Ganpr1 PGASQADIIRANQKDEQLQQQITQVVVASLVYYCLTTGSQTLGEEYCDIPPVSKRPYLLSLHLAIFYFGIYYTIAKRLGWRYISYEPMGLVIVLQTIVEKKCTLCLEPRPAATECGHVFCWRCISEWINESAHLYPL Gloin1 ---------------------MTNTFRSDLFYFCLTAGTQTLGEEYCDIPSASKRPYLFTVHLAIFYFGAYYFISKRAGIRYIGYEILGFLLVVQFIIQRKCILCLSPRTTATPCGHLFCWTCIVDCCNNKSHLLPI Hisca1 PWATSPDVIRSHEKDAYLSVQAHTIIRTDLLYFSVTTGNRTLGEEYCDVPSLVRRPWTLQLNLAAFYFGAYYHISKRIGLRYVGYEVLGVLLVLQIAVQRKCTLCLELYPSATTCGHIFCWTCIRDWVREKSKILPL Klula1 PFADAPSIVQAHQKDDTLLQKIQDVLRSKLIYLSITTYRRTLGEEYVDLARLLRRPWILSLHLIIFYLGQYYDISKRIGMRYVNYKILGFILGMQLASKRKCVLCLNYMPSATPCGHLFCWDCIMEWTLERQLTIPV Lacbi2 PHAQQAQIIRANQRDVYLRDQTDTVLRVKLLYYGLTTATQTLGEEYTDIPSPLARTYLLGLNLAFFYLGTYYDPVKRLGIQHISYSLLGVLIGVRLLYRRNCTLCLEERSCVTECGHLFCWSCIVGWGREKSRLLPI Lenti61 PQAQQAQIIRSNQRDLFFREEAENVFRANVLYYGLTVGSQTLGEEYTDIPNPRLRSYLLSINLAIFYLGTYYNLVKRSGIKYISYALLGILLAVRLLHRRNCTLCLEERSCATDCGHLFCWNCIVGWGREKTSLLPV Malgl1 PRSAQAEIVRLHQKDTYFHEQLKEFAISSLVYFGLCTGAQSLGEEYVNAVSAKRRPYIVAAQLAMFYLGRYYTLAHRFGADYMSYEVLGVLLTIQFLVKLRCTLCMDRRSAVTECGHVFCWACIEEWLSEKTQLMPI Mellp23 PNAAQPEIIRADQKDAYLQDMLESSIRVHLFYYILTTASQTLGEEYCGIPSWKRRTKLLSLHLAIFYLGRYFHLSNRLGIRYVSYEFLGLLIVIQLIVKSRCTLCLGPRQSSLECGHVFCWRCILGWVREKTSLALD Mnele ----------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------- Morel2 PSASQPDIIRANQKDSYLKDQVKDAVRSDLCYYTLTTGTQTLGEEYCDIPSFPRRPYLYSAHLAVFYFGAYYSFSKRVGIRYIGYEVLGVLIVIQLAIQRKCTLCLDPRTTATPCGHLFCWTCIREWCQNKSALLPI Mucci2 PYGAQPDIIRANQKDVYLQEQMTRVAQSDICYYGLTTGTQTLGEEYCDIPGLVRRPYIYTVHLAIFYFGAYYNFSKRLGIRYIGYEVLGVLIVLQLLIQLKCALCLEQRTTTTPCGHLFCWNCIVEWCQNKSHLVPL Mydma DYADYKAPIKANLKSTA------------IQYFIMVV-----------------------INMLAFYIGGNFSIAKRIGIKNWTFHWLANLEFIQLVT-TKCILCFQRIASSTFCGHVFCWQCIIEWTTAKSRIIHL Neucr2 PFAAAPDIIRAHQKDAYLTNQLTDLHRADLLYLCLTTGNRTLGEEYCDLPSLQRRPYLFSLTLAVFYFGAYYSFSKRLGLRYVGYEVLGVLLVVQMLVRRMCTLCLEELPAATQCGHVFCWSCIGDWVREKQHILPL Orpsp11 PYASQSAIVRSVQFDEYLIDETKNLFKSRFLYYILTSGSQTLGEEYCELPSKLKKPQFMSVHISLFYIGRYYEIAKRINNRYIKYEALGYIILFEIFMKRKCTLCLEFCISVTNCGHVFCWNCICEWCQKKSQLYRI Pench1 PFATSPDIIRSHEKDAFLVQQSQGIVRTELLYFTLTTGNRTLGEEYCDLPSIGRRPWTLQLSIATFYFGSYYHLSKRLSLRYVGYEVLGVLLVLQIAVQRKCTLCLEMFPSVTTCGHVFCWICVRDWVREKSKVLPL Phybl2 PRGAQPDISKANQKDVYLQEQMKSACQADFSYHGLTTGTQTLGEEYCDLPSVLRRPYLYQLHLALFYFGTYYSFSKRLGIRYIGYEILGILIVLQLVIQQKCALCLEPRTTATPCGHLFCWSCVVEWCENKSHLIRL Picst3 PFADAATIVRAHQKDAYYRSQLLDVIQAKSAYLALTTGARTLGEEYVDLPKLLPRPYLVLLHIAIFYFGEFYSLSKRVGLRYANYSLLGAIILLQFAVKRACMLCLSPMPAAANCGHMFCWDCIVGWIREHQNLLPL Plicr1 PAAQQAQIIRANQRDTYLKDQTESVLRTKVLYYGITTATQTLGEEYTDIPSTRLRSYVHALNLAIFYLGTYYDLSKRVGIRHISYALLGILLGVRLIHRRNCTLCLEERSCATECGHLFCWSCIVGWGREKTRLLPI Polpo QYADQPDIVRASQKDDFFEEQVFEILTSSLTYYILTTGSQTLGEEYCNLPTIA--PYIIKLHLALFYFGAYYEFSKRLNIRYIKYHILGLLIIIQLLVSGKCTLCLEVRSTSTICGHLFCWYCLSEWCNSKQSLMPI Pucgr2 PSAAQPEIIRADQKDAYLFDQIEPLLRSKLIYLSLTTGSQTLGEEYCDIPALYRRPRLLSLHLSIFYLGRYFTWSKRFGITYISYEILGVLMVIQLVVKRRCTLCLGPRQTSLECGHLFCWRCLVSWIREKAELLPL Punst1 PRAQQAQIIRANQRDLFLREQTENVFRTKLVYYGFTTATQSLGEEYTDIPGWRLRSYVLAVNLAVFYLGTYYDVWKRLGIRHLSYSLLGVLLAVRLIHRRQCTLCLEERSCATECGHLFCWNCIVGWGREKARLLPI Rhior3 ----------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 ASAAQPEIVRANQKDLYLSERIEDVARSRLAYFGLTTGSQTLGEEYCDIPTLPRRPYILGVHLAIFYLGRYYSLSKRAGIRFISYEVLGVLMGVQLVVRRRCTLC------------LVCWECVVGWAREKSKLLPL Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------- Sacce1 PFADAPSIVQAHQKDEQLIMKVTELCKAKLLYLLFTTRGRTLGEEYVDLAGRLKMPYFITVHMTLFYFGAFYSISKRIGMRYVKYKVLGYILLAQNVMKRKCILCLMNMPSCAPCGHLFCWSCLMSWCKERQEILVL Salro ----------------------------------------------------------------------------------------------------------------------------------------- Schco3 PPAQQAQIIRANQRDLYLREQTENVTRVKLAYFGLTSATQTLGEEYTDIPPTPIRPYLLAVNLAIFYIGGYYDLWKRLRVTHISYSLLGVVIGMRLIYRRNCTLCLEERSTVTECGHLFCWSCIVGWGREKTKLLPV Schpo1 ---DPLQIILCTEIDEAIKSQIEGIARGKFLYRACCL--ATMGEEAARIATTGERPFGLRIRFLCLTMGHCATVSQLLGLKYIKVLTLLLLLGSRLIASRKCSLCMEFIPAATECGHIFCWSCINGWTSKKSKIILL Sorma PFAAAPDIIRAHQKDAYLTNQLTDLHRADLLYLCLTTGNRTLGEEYCDLPSLQRRPYLFSLTLAVFYFGAYYSFSKRLGLRYVGYEVLGVLLVVQMLVRRMCTLCLEELPAATQCGHVFCWSCIGDWVREKQHILPL Sphar ----------------------------------------------------------------------------------------------------------------------------------------- Spipu1 PYGSQPDVIRANQKDVYLQDQFSSVFRSDLTYYGLTTGSRTLGEEYCDIPSAMSRPYIFTLHLALFYFGAYYHVSKRIGIRYISYEVLGMLIVVQMLVQQKCMLCLSPRTTATPCGHLFCWNCIAEWCRNKSHLYLV Sporo1 AHAAQPEIVRANQKDLYLSEHFEDVARSRLAYFALTTGSQTLGEEYCDIPSRARRPYFLAIHLTVFYLGRYYNLSKRFGIRFISYEVLGVLMAVQILTRRS-----------------FCWECVVGWAREKSTLLPL Stehi1 PAAQKAQIIRAHQRDFILKEQIENVLRVKVLYYGLTTAIQTLGEEYTGIRIHYIRAYLLALNLAVFYLGTYYEGVRRMRIRHVSYSLLGVLIIVRLLYRRNCTLCLEERSAATECGHLFCWSCVYGWGREKTRLLPV Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------- Thetr HVAAPERVLRARQKDGQLRGRLEELVRASLVYYGLTKCQPSVGEEYGYVP-LVRMPLLVALHEAWFF-GSYASIADRLGIVHA---YVG-MAVLHAIPP--CPICFEDMVSATLCGHVACWDCLIQFTASDSDVVRL Treme1 PPASQAQILRAQQRDSSLTELAAELLRTRAVYLFLTLGQQTLGEEYTDIPSRTRRPSILTLHLVAFLLGRFFDLARRLGMTYISYEPLGLLLLIALLNRRQCTLCLEPRVGVTECGHVFCWGCLGGL--DKERLVAA Trire2 PFAAAPDIVRSHQKDAYLANSLTDLHRASLLYFGLTTGNRTLGEEYCDLPALPSRPYLASVVLALFYFGTYYELTKRISLRYVGYELLGVLLAIQMAVQRKCTLCLEEMPAATQCGHVFCWECIGDWVREKQHILPL Umbra1 PAGAPPDIIRANQKDVYLQEQMTDVFQSDFCYYGLTTGTQTLGEEYCDIPGLLRRPYIYTGHLALFYFGSYYSISKRIGIRYIGYEVLGLLIGVQLFIQLKCALCLEPRTTATPCGHLFCWDCVVEWCQNKSHLIPL Ustma22 PAAAQPEIVRAYQKDTYFTSQVSDVVRGALGYYLLSTGGQTLGEEYVNAVSLPKRPYSLTAHLMLFYLGKFYSAAQRLGVTYISYEVLGVLLGIQLSVKLQCTLCMDQRSAVTECGHCFDWSCITAWIAEKHRILPI Walse1 ---DEAYIIRSDQKDLYLRTLAEPVLRLLTVYTAITTGRRTLGEEYTNILSWQMRPHILKLNLIAFYLSKFHTIKNRINIRYIPFEILGYMLSIRLAIQRKCILCLETRTSAMLCGHLYCWYCLENWLREKKDVIPV Zygro1 PFADAPSIVQAHQKDDQLSGKIEEVVKVKLLYLSLTTGNRTLGEEYVDLVQRYKKPYLGSVHMMIFYFGAYYDIFKRVGLRYASYKILGYFLLFQSVFKRNCILCLNEMPSCPPCGHLFCWACIMNWCKERQQILPL [Cluster2405.fasta_al_trimmed; alignment length = 83] Allma1 RLVKNVLQLGEVKAGTLIGTDQGNRYYENREELFARERWVVPSEIPAGWHTWIHRIDARA--PHSGSEA-NYKPYSTT-EPKI Ashgo11 ----------------------------------------------------------------------------------- Aspfu1 RTLRNLRRIGDTKAGTLIATDRGNKYYENMEELPLRTRWVDYSQIEPGWHAWLSYMVDAP--PTTLSRG-AYKPYSTV-KPKY Aurde31 RTLRSIRRIGDAKSGKFMGSDEGNRYFENTNEIPGRHRWVDFTQVPPEWHSWLSHIRQLP--PNTGTRG-AYRPYNTA-GPKM Batde5 GVAKSIQNIGQPKTGTLVGTDKGNKYYENPEDMQGRNRWVFYTQAPPEWHQWLHRISDDI--PTTGTRG-AFKTYNTT-VSKI Botbo1 RTINNMRRIGDAKYGAYVGKDQGNRYFENYDEVPGRHRWVDLSQVPPEWHSWISHIRKDP--PTTGTRG-RYKSYNTA-APKI Botci1 KTLTAMLFTGDTKAGTFIAKDRGNKYFENLEELPLRTRWVDYCQIEPGWHAWISYMVDKP--PTTMSRA-AFKTYSTV-KPKI Caeel QMVKEI--MDATRVGTLVGSDNGNRYYENNAYFVPRNRWVEFTQVPPEWHSWLHHITDDA--PSSIYADKKYVPYSTT-RTKI Canalb1 RTLKNIYSHNDTKRGWLVGIDDGNKYYETDAEIHLRTRWVEYSQVEPGWHYWLGYGTNTP--PNTNTPG-AYVCYNTA-KPKF Cangl ----------------------------------------------------------------------------------- Capow LAMK----ESDIRGGTLVGEDQGNKYYERPDHVFGLNRWVDYSKIPPEWHRWIHNMCQEP--PQTGTAK-AYMPWSTT-KAKI Catan2 RLITNVAKLGEVKSGTLVGTDHGNRYYENLNELWQRERWVVPTDIPAEWHMWIHKVDSRT--PQTGSIA-NYKSYDTTPEPKV Cioin EMMKHFRHMNEIKYGTHVGTDEGNKYYENNRYFVGRNRWVDFSQITPEWHRWLHYMTDDT--PTTGTKD-CYVPYSTT-KPKI CocheC53 RTLRNLRRIGDTKAGTLIGTDRGNKYFENLEELPLRTRWVDYSQIEPGWHAWMSYMVDKS--PATWSRS-GYKPYSTV-KNKY Coere1 RFLKFSLRLDDAKWGRLVGVDEGNRYYENPEERYGRERWCLPSQIPPRWHSWLHKTTDEV--PKTGTKK-ANVTFNTV-RPKV Conco1 ----------------------------------------------------------------------------------- Conpu1 SAAAQYST--------------GNVYYENLNEIPGRHRWVDFTQVPPEWHSWLSHIRQLP--PTVQTMI-SHS---------- Copci RTIRNIQRIGDAKSGRFVGADQGNRYFENRNEVPGRHRWVDFTQVPAEWHAWLSHIRKDP--PTTGTRG-AYKSYNTV-VPKI Croqu1 RSVRNFLAICDPKPGQLRGTDEGNRYYEDPSESFYRNRWVDFSQVTPEWHSWLSHIRKDP--PHTGTRG-AFKTYSTT-SPKI CryneH991 RTFRHFRLIGDAKYGRLVGTDQGNRYFEQLDEIPGRHRWIDYSQVPPEWHSWIHHIRKDA--PTTGTRG-HFKTYSTT-APKI Crypa2 RTLGNLRKIGDTKAGTLIGTDKGNKYYENMTELPLRTRWVDYAQIEPLWHAWMSYAVDQP--PTTQTRG-AYKPYNTV-KPKI Debha1 RTLKNIYSLNDTKRGWLVGQDDGNKYYETNVEIHLRTRWVEYSKVEPGWHYWLGYGTNTP--PNTGTSG-AFVTYNTS-KPKH Dekbr2 RVFKNFYRMNDTKSGHIVGVDDGNKFYETSNEIHMRTRWVEYSQIEPGWHFWLAYGTDTP--PNSCTRG-AYVPYNTA-KPTL Dicdi RYCQGIMQTGELKFGTLVGVDKGNRYYENRQEIYGRHRWVEYTTIPPEYHSWIHHVSDKL--PSTGTDG-AYTPFNIE-KSK- Dmel QMVREA--NDDLKIGTLVGIDKGNKYFENPYYFYGRNRWIEFSMIPAEWYGWMHYKTDLP--PISGTKE-AYYPYSTT-PNKV Enthi ----------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------- Fomme1 RYIRHIRQIGDAKAGTLVGTDQGNRYFENLNEVPGRHRWVDYSQTPPEWHSWLTHIRKDP--PTTGTRG-AYRSYNTA-APKI Fusgr1 RTLTNLRKIGDTKAGVLIGTDRGNKYFEN-NELPLRTRWVEYAHIEPGWHAWMSYSVDKP--PTTQTKG-AFKTYNTA-KPKM Galma1 RTIRNISRIGDAKAGTFVGKDQGNRYFENRNEIPGRHRWVDFTQVPPEWHSWISHIRKDP--PTTGTRG-AYKPYNTV-VPKI Ganpr1 RTISGVLSIHDPKIGTLIGQDHGNQYYENRNEAWGRHRWVEYDRVPAEWHGWLSKSHDDP--AH------ALK------KAK- Gloin1 RTIKNFLKIGDTKAGKLVGTDKGNKYYEDKEEFFGRDRWVDYSQIPSQWHAWMHKIVEHP--PTTGTRK-AFRTYNTT-APKI Hisca1 RTARNLWRIGDTKAGTLIATDRGNKYYENM-ELPLRTRWVDYSQIDVGWHAWLAYMVDKP--PTTLTRG-AYKPYSTV-RPKY Klula1 ----------------------------------------------------------------------------------- Lacbi2 RTIRNLRRIGDAKSGTFIGADQGNRYFENRNEIPGRHRWVDFSQVPPEWHSWIQHIRKEP--PSTGTRG-AYRPYNTT-VPKM Lenti61 RTIRSIRRIGDAKSGRLVGKDQGNRYFENLNEVPGRHRWVDFTQVPPEWHSWLHHIRKDP--PTTGTRG-AFKTYNTT-RPKY Malgl1 ----------------LTGMFDGNTYWENNEEQPGRTRWVDYTQLDPIWHAWLSHTRCEP--PSTGTRG-AYRPYNTT-KPKL Mellp23 RTFRNFLAICDPKAGQLKGTDEGNRYFEDPNESFYRNRWVDFSQVTPEWHSWLSHIRKDP--PQTGTRG-AFKTYSTT-GPKI Mnele GFFKKM--CNEFRYGTLVGTDDGNEYYENNDYFLGRNRWIQYSDIPAEWHAWMHYMTDDT--PISPIFKERYTPSTTT-KPKI Monbr RQIQQV--EGKLMTGVLVGQDKGNKYYEDKEQMFGNHRRVDMSQVPPEWHRWLHAMTDDL--P-TDSAD-RYVAYSTV-KPKI Morel2 RTINGFLKIGDTKVGTLIGTDKGNKYFENLNESYGRTRWVQFSQVPAEWHGWLHRMLDAP--PTTGSPQ-AYKTYNTT-RSKF Mucci2 RTIKNFMKICDTKWGRLVGTDVGNKYFENLDEVSGRERWVEYGDITPDWHMWLSRITQEP--PTSGTPK-AFKTYSTT-ISKL Mydma DCVKVMHY----------GTDKGNKYYKNNSYFMGRNRFVEYTQIPPEWHAWMHYMTDDT--PISGTKN-AYIPYSTT-KPKI Neucr2 RTIRNLRKIGDTKAGTLVGVDKGNKFFEN-QELPLRTRWVDFSHIEPLWHAWISYAIDTV--PTTTLPG-AFKTFNTV-KPKI Orpsp11 ----------------------------------------------------------------------------------- Pench1 RTLRNLRRIGDTKAGTLIGIDRGNKYFENL-ELPLRTRWVDYSHIEPGWHAWISYLVDGP--PHTLSRA-AYKTYSTT-RPKI Phybl2 RTLKNLIKIGDTKWGRLVGTDVGNKYFENLDEVSGRERWVEYEDITPEWHGWLTRAFQEP--PTTGTPK-AYKVYNTT-VSKL Picst3 RTIKNIYKHNDTKSGWLVGEDDGNKYYETDAEIHLRTRWVEYSKVEPGWHYWLGYGTNTI--PTTNSSG-AYVSYNTA-KPKH Plicr1 RTLRNIRRIGDAKSGRHVGTDRGNRYFENLNEIPGRHRWVDFSQVPPEWHSWISHIRKDP--PTTGTRG-AYKPYNTV-KPKI Polpo RYFKGILQTGELKYGNVIGKDVGNSYFENLNEPHGRHRWVEYTTVPPEWHSWLHHISDKHGNSQTGTDG-AYTPYNIE-KAKD Pucgr2 RTIKNFLAICDPKPGAFRGIDEGNKYYEDPSESMFRNRWVDYSQVPPEWHSWLQHIRKDP--PHTGTRG-AFKTYSTT-LPKV Punst1 RTVNNIRRIGDAKYGALKGTDQGNKYYENLNEVPGRHRWVDFTQVPPEWHSWLSHIRKDP--PSTGTRG-AFKTYNTA-APKI Rhior3 RTLKNFIKIGDTKWGRLAGIDAGNKYFENNDEVSGRERWVEYGDIAPDWHMWLSRIVQEP--PTSGTVK-GYKTYNTT-TPKL Rhoto1 RVINNIRQIGDFKAGKFMGQDEGNKFYENRDETQWRHRWVDFSQVTPEWHAWLTHVRHDP--PTTGTRG-AYKCYNTT-KAKV Rozal11 ----------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------- Salro KLIQRV--EGKVMPGTLVGVDKGNRYYEDRTQMFGQHRRVDYSQIPGEWHRWMHYMTDDL--P-TGTTK-QYVPYSTT-KPKI Schco3 RFVRNVYRLNDVKAGRFIGADQGNKYFENMNEVPGRQRWVIFSQIPPEWHSWLQHIRALP--PTSGTRG-AYRSYNTV-KPKI Schpo1 ----------------------------------------------------------------------------------- Sorma RTIRNLRKIGDTKAGTLVGVDKGNKFFEN-QELPLRTRWVDYSQIEPLWHAWISYVIDTV--PSTAQMG-AFKTYNTV-KPKI Sphar NRIKEL--YKELRTGTLIGTDAGNRYFQDKSYIFGRSRFADVTSIAPEWHRWLHYMTDDP--PSTGSKN-EYVPFRTT-AKKV Spipu1 GTLAALRAIDQPRVGRFVGKDDGNEYYENRDEIVLRDRWVEYTQVPAEWHQWLHHITDDV--PTTGSEG-AFKTYNTT-VPKY Sporo1 --------IGDVKAGKFMGQDEGNKFYENQDETLWRHRWVDFSQITPEWHSWLSHMKHLP--PTTGTRG-AYKPYSTT-TKKV Stehi1 RYIRGIRAIGDVKAGRFVGKDQGNRYFENLDEVPGRHRWVDFTQVPPEWHSWLSHIRMDP--PTTGTRG-AYRPYNTV-KPKI Tapde11 RTIRNLRQIGDTKAGRLVGIDKGNKYYEN-NEVPFRNRWIDYSQIEPGWYSWLKHTLNDP--PTTMSRG-AYKPYSTV-KEKI Thetr SIARNMLRSGTVKGGRFVGKDQGNEYYEDLEDLYGKNRYVLYTAVPAEWHSWMCQMKDTP--PSTGTAT-SYTATNSLDGVKN Treme1 RTIKNIRQIGDAKAGRLVGQDAGNKYYENLNEVPGRGRWIEYSQATPEWHSWLHGIRHLP--PTTGTRA-AYKPYSTT-PPKL Trire2 RTLGNLRKAGDTKHGTLVGQDRGNKFYEN-TELPLRTRWVDYAQIEPGWHAWISYAVDKP--PTTMTRG-AFKTYNTT-KPKL Umbra1 RTLKNIMRMGDTKFGALIGTDAGNKFFENNDEIFGRERWVEYAQVAPDWHMWLTKFVQEP--PTTGTRN-AYVPYNTV-RPKY Ustma22 RTINYIRKIGDAKSGRLVGIDRGNKYYENHNEFNLRHRWVDYSQVDPLWHSWLHHIRKDP--PHTGTRG-GFKTYNTV-KPKI Walse1 RHLRNWYRWVDVKAGRLAGTDKGNRYYENLEEVPWRQRWVRYSQVPSEWHAWLHHTRLNA--PHTGTRG-AFTTYNTT-APKL Zygro1 ----------------------------------------------------------------------------------- [Cluster2413.fasta_al_trimmed; alignment length = 84] Allma1 VPQIKRIVFNYCERSGSSRGLIDFFQRLVQFAEAHPHVEMVVISGRQKVLCVKNMSSKEIQEHIKLLTEAADTPAVRGIWSPFK Ashgo11 IFPCKKITLQYCNWGGSSQGLRDFLTSLAKWAEKYPQIQFEVINGLNKAICVRNLNVDHVELKLKLLRESSGNQSVRGVWSPLH Aspfu1 ILQCKRLDFHYCDWAGSSRGMVAFLKHLPSFAKANPQIEIRVINGREKAICVRNMEPEQILKKANLLKEASGNESVRGIWSPYH Aurde31 IPQIRRLVFEFCDRRTTSARTRLFILRIEQLARDNPHVEFVVVNDRDKVIELTQLEPPSIMQKVQLLLDSSGTSSARGIWSGLH Batde5 VPSICRLKIFYIGAGGTSRSMVDFLKHITSLAQSRPYIEFNVNNGSTRNIICSKLNAKQIKEKTAELCDGSGRDLVNPTWNPFH Botbo1 IPQIRKLVFEFCENWPSSANLRTYLLNAYTVARENPHVEIVVLNDRTKVIGLKGFEATGISQKVQLLLDSSGTESARGVWSGLH Botci1 ------MDFHYCDWAGSSKGMNTFIKNLPGFAKANPQIEITVINGREKAICVRNLEIGQILKKAELLRDASGNESVRGIWSPYH Caeel TNQLHRITVRFCKQSESSVGVRNFIENLVEIGRKNPSVVIYAGNGRTLQINAKNMTQDEVSKDVHLLFSRSGVPSIQGQWTPIT Canalb1 VNPCHRITVQYCNWGGSSTHLRELLTNLNNYAKSKPDIFFEINNNVTKEVEIKNIKQNEIIKTLTEYSQRSGNDSVRGIWSPLQ Cangl VQPCKKVVLQYCNWGGSSAGMRAFLRSLDMLAAKEPHIQFEVTNGREKVICVRNQNIDNVENKIKLLKDCSGNQSVRGIWSPMH Capow IPQLRKLTLHYCRNSPSSIGMREYIDRVVKLAQDNPAIVIQVLAGASRTVGARNLTANEVEQSVERLRGLLGNPSVQGTWQPFL Catan2 VPQCKRIVFNYCERSGSSAGLIQFFKTLHKFALQHPHIEFVVISGREKVLCVKNMSPAEIKQHIRLLTEAADTPAVRGIWTPFK Cioin VKQLKRITLNFSEASPSSRHVRKFVENLVEFARKHPSVVVYALNGREEVASLEKLEPDEILQKLDTYSNRSGHPSIQGQWHLF- CocheC53 VLPCKSLTFHYCNWWGSSRGMNAFIKSLPAFAKRNPQIEISVINGAQRSICVKNLQNEGVREKAEMLRNSTGNESVRGIWSPFH Coere1 ---------------------MEYLQKAIDFAKKNPQIEVVVTNGFQKTKCVRKCTVEEIPEVVKSLRDHSGTPSVRGIYSPFH Conco1 ------------------------------------------------------------------------------------ Conpu1 VPQCRKIVLSFCQRFPSSTNTRTFLLNLERIAKKNPHVEFVVVSGRDKVIPLNGFEPNGIEKKINLLLDSSGQESARGIWSGMH Copci VPQIRKLVFEYCNSWPSSQNTRTYLLTLQALARENPHVEVVVANGRDKVIPLQRLEVNGIQKKIELLLDSSGTESPRGIWSGLH Croqu1 ILPLRKLVFEYNEQRANQAGLRAYLTSLFQVANQNPSVEVVVNNNRTKVIPLDRLDPSQIHLKVQLLLNSSGSEPVRGVWSAFH CryneH991 LTPLRKLIFDYDAEAPSQHGIRSYIRKLLDMARENPDVEIVVVNGRDKVICVNKLEANEVANKVDLLLNSSGAESARGIWSALH Crypa2 VLQCKKMDFHYCDWAGSSRGMNKFIEMLPKFAARHPEIEISVINGNTRPVCLKKMDPNQILSKLEMLRDSTGNESVRGVWSPYH Debha1 VLPCHKISVQYCNHGGSSSGIRDLLASLNSMASAKSKIFFNINNDHNNQVSIANLPASEIVNKINEHSQSSGNESVRGIWSPLH Dekbr2 VLPCKKILITYCDFGGSSVGMRDFLRSLKGFASQYPEIEFQVTNEKSKQICCRKWNADVIENKLKLLINSTGNSSVRGIWSPFH Dicdi VWQLKKLAINYCEFSGSSKYVRNILNSVEKFKSVNPQIEFEYESGVTKTVPLRGRTEEKVLKHIQNLKDTSGTESIQGLWNPFI Dmel VCQLQRITLKFCKNNGSSRGMRDFIENLLDFAKENPGIVVYVLNGEREWMSCRNSTQEEISKWIDLLKTQNGVPSIQGPWTPFL Enthi ------------------------------------------------------------------------------------ Falba VQPCHKIMINFCKHSGSSRFVRNYINEIVEFARQNPSIVIAVLNGSQKSIGVKNLPEEKVHEFMMFLRSHNG---------PI- Fomme1 ------------------------------------------------------------------------------------ Fusgr1 ILQCKKLDFYYCDWAGSSKGMNGFIKSLPKFAAANPQVEFAIINGLHKPICVRNLSPYEILKKAELLRDASGRPSVRGVWSPYH Galma1 LPQIRKLVFEYCDKWPTSANTRTYISNIEALAAANPHVEVVVVNNRDKVIPLKSLEVTGIQQKVQLLLDSSGTEATRGIWSGLH Ganpr1 ------XLFLYWGRGGSSTGLVDFITRLPRVARENPTXEFCVANGEHKYGLVRNFSEKDVADEVAKLKDASG-------WTPSQ Gloin1 VFSCRKIEFNYCERSGSSYGMIKYLQNLIPFAKINPQMEIVVLNLKKKQVCVKNKNPDEIAEIVKLIRDNTGTKSIRGIWSPFH Hisca1 ILQCKRLDFHYCDWAGSSKGMNAFLKYLPSFAAANPQIEIRVINGREKAICVRNLEKEQILAKALLLKEASGNESVRGIWSPYH Klula1 VLPCKKITLQYCNWGGSSQGLRDFLTSMIQWAEKYPTIQFEIVNGRNKAICVKNLNIDNVENKLKLIRDASGNDSVRGIWSPLH Lacbi2 LPHIRKLVFEFCNKWPSSENTRTFLLNLQSLARQNPHVEIVVVNNRDKVIPLNSLEVTGIHKKVRLLLDSSGTQAARGIWSGLH Lenti61 IPQIRKLVFEFCDNWASSANLRTYIHNLEDLARANPHVEFVVINNRDKVIGLKDFEVTGIDKKVQLLLDSSGTEATRGIWSGLH Malgl1 AIPCRKVVVEYCEKSVASKGTRDYLLQAVSIARAYPSVEFVV--------------PTQVGPKMQLILDASGNESARGVWSPMH Mellp23 ------------------------------------------------------------------------------------ Mnele TPQCKRVTFRIHPTAPDSFHAREYLQNLSATAEKHSTVSFYVLNGYQEEQRIDNVHEDVLSQFVEKYCNYSGTRSIQGMWSPYM Monbr VPQLRLLRASYCKGGDSSKGMREYIQSLPSVAEEAPWTVFRVLNGRTRKFCVKNMSTVEIDGLMSRLQAEEGRPSIQGTWNAFL Morel2 IPQCRRLVFHYCERSGSSRGMIEYLKKLIQFAKEHPHVEVIVLNGKDKVVCVRNMEPTDIAGKVALLKESAGTESVRGIWSPFH Mucci2 VLQCRKMVFNYCEKWGSNKGMVEYIKKLAEFAKQHPQIEIVVLNGRDKVICTRNLTPGEINTKVELLRDSSGTESVRGIWSPFN Mydma VCQLKRLTFNYCTYSGSSRGLRYFIDFAEKFVKDNPQTSVYFMNGQDRIISVPNHDSIAIWDWLERLKNESGTPSIQGTWNPFL Neucr2 VLQCKKLDIHYSDWAGSSRGMNGFIKSLPKFAAANPQIEFVVINGRTKAICVRNMEPLEILKKAELLRDASGNPSVRGVWSPYH Orpsp11 ------------------------------------------------------------------------------------ Pench1 ILQCKRLDFHYCNWAGSSKGMVAFLEKLPTFARENPQIEIRVINGREKPVCVRNMEPHEILKKANLLKEASGNESVRGIWSPYH Phybl2 VLQCRKMVFNYCEHWGSNKGMVEYIKKLVKFAQENPQVEIVVLNGRDKVICTRNLNTAEIANKVALLRDSSGTESVRGIWSPFH Picst3 VLPCHKISVQYCNWGGSSSGLRQLLKSMDSIASQKSGVVFDVNNSQKQEVDIANLEASQIVEKLNEYSQRSGNDSVRGIWSPMH Plicr1 IPQIRKLVFEYCQSWASSHNTRTFLVRLANVARQNPHVEVVVLNNREKVIPLNGFEVTGIQKKVELLLDSSGTESTRGIWSGLH Polpo VWQLKKMCITYCEHSGSSKYIRNILPTFIKFKEANPQIEFEELSGKEKFLPLRGREEEKIIKHLQNLRDTSGTDTIQGLWHPFL Pucgr2 ILPIRKLLIEFNQQRQSQNGLRNFLSLLYKLVKQFPFVEFVVNNNRIKTIPVDGLDPNQIQKKIQLLLESSGKNPTRGHYSALH Punst1 IPQIRKLVFEYCDKWPSSHNTRTFLETVEDLARANPHVEIVLMNGRDKVIALNKCEVHDVGKKVQLLLDSSGTEAARGIWSGLH Rhior3 VLQCRKMVFNYCEKWGSNKGMVDYIKKLTKFAAENPQIEIVV--------CK-------------------------------- Rhoto1 ILPCKKLVVQYSEIQGSNRGMRDFIGQPVDIARRYPGVEVVVNNGRTKEICVRNLPPNSILAKAQLLLDSSGTESVRGVWSAFH Rozal11 ------------------------------------------------------------------------------------ Sacce1 VFPCRKITLQFCNWGGSSEGMRKFLTSLDKWGQEFPWIQFEVTNGREKVICVRNLNIDNVENKLKLLKDSDGNSSVRGIWSPLH Salro VCQLRKVTLSYCRGGVTSQGMRELVDGLVDFCQQNPHIVFQILSGHSKSVSVKGKSASDILDAVKQLARESGNPSIQGDWHAFL Schco3 LPHIRKMVFEYCEKWPTSANTRTYLVKLEDLARENPHVEIVVVNNRDKVIPLRDLEVNGIEKKVQLLLDSSGTESARGIWSGLH Schpo1 TRPCRRIEFSYCNWGGSSKGMKEFLSTLESLAKESQDVEFHVNTGREKVICTRKMSASSIFQKAILCRDSDGNPSVRGIWSPFS Sorma VLQCKKLDIHYSDWAGSSRGMNGFIKSLPKFAAANPQIEFVVINGRTKAICVRNMEPLEILKKAELLRDSSGNPSVRGVWSPYH Sphar ------------------------------------------------------------------------------------ Spipu1 VPQITKLTIHYIDAGGNSRGMVKFLLDLPTLAAERPYVEICVANGKVKAISCSKFTPEQIEKQVAFLCDSMDAGRVEGVWDPFT Sporo1 VLGCKKLVLSYSEVQGSARGMRHFLASASEWARQYPGVEFVVLNGRSKEICVRSLEPSSISQKIKLLLDSSGNESVRGMWSAFH Stehi1 IPQCRKLVFEYCDKWPSSANARTFLHNLEDYARAHPHVEIVVLNDREKVVGLKGYEVTGIQQKVQLLLDSSGTESARGIWSGVH Tapde11 ILQCKNIEFGYCEWAGSSRGLNRFLQTLPRFAAQNSQINFSVINGREKVICVRNMDESEILQKCELLKNSSGNESVRGIWSPFA Thetr LVQLARLTLRFCGASGSSSQARVYVEKLEELAAKYDAAFVAAANGTTQVVPLRKLSVEQIDAQLDALAQRRGQGSVQGVWGGLG Treme1 LTPLRRLVLDHDPLSPSQHGLRTYLKTLIQLAKENPDVEIVVVNGRDKVICVNGLETNQVAQKVKLLLDTSGGESARGVWSALH Trire2 --KCKKLDLHYCDWAGSSKGMNGFIKSLPKFAAANPQIEFAVINGRTKPICVRNLSPYEILQKVELLRDASGKPSVRGIWSPYH Umbra1 VLQCRKMVFNYCENWGSNKGMINYLKKIVEFAKANPQIEVVVLNGREKVICVRNMAPFEIKQKVQLLKDSSGTESVRGIWSPFH Ustma22 HLPLRKLVLRYSQTNASSAGMRTFLLSFGLLTQKYPSVEFVVTSGRSKQVNLANLDAGQVEAKLKQVVESSGNHAARGVWSQLH Walse1 VPQITRIIFAVDDFAPSHQSLRSFLRYLNDTANNNKHVQFVVINGREKVIATNRLNAHSVKEKVQLLLDSSGNESVRGIWSPYH Zygro1 VFPCKKITLQYCNWGGSSQGMRDFLVSLGKLSQDLPQIQFEITNGREKVVCVRNLNVDNVENKLKLLKDSSGNNSVRGVWSPFH [Cluster2415.fasta_al_trimmed; alignment length = 262] Allma1 VQVDALVALKIAKHAKDLPAA-VTGALLGMDEVTQSYYQVDMLKCLRQVNTVGWYHAAPLSHFL-QYSWVA-NQAEYQTSIPQ-SVVLEYDPLASQ-TGTLALRAFRLTDAFYALLSKHSINSEAVTASGLLESGLIEELPVTIRNAHVVSALLYSQNL------PGVDRSVAKHANALLETLDHRAYTRDKARMDAHRKRQEN----------P--AEAQLAAKLPN-EPSKVDSLLQAGQHCELLDAFLAPAVLSVETAR Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 VKVEALVVMKIMKHCSQTPTT-ATGSIVGMDEITNSFYQAEMIRMLREVNNVGWYTSANMGNFV-NMNVIE-NQFFYQKEMNERTVALVHDVSRSS-QGSLSLRAFRLSPKFMTAFKENKFTSEELQKSGLRYQDIFVELPVEIHNSHLITSFIHQLQTPLAPNFDNLALSLEKNCDLLLDSIEQRSLAREQQRISAQKRKQENATRAALKPLLP--EDEQRLFKLPQ-EPSRLESMLQVDQYARQIDSFVSSTTGKMFAVK Aurde31 VQLDGMVVMKIMKHARDASGT-ATGLLLGLDEVSNSFYQASMLKLLEGVDIVGFYQSSALGAFF-QQSLVD-LQTSHQERLRHGGIVVVHDTSAAA-RANAVFRAFRLTPAFLDASRKDKFGTQSLIKHELIFSRIFEEIPVSVRNSPLLNAFMNTLTTPLSPPFAPLDLDVTRNLEAILETMEHRQITREKAKADAAKRKEESAMRVAQGAPLP--EEDSRLFRIPA-EPSRLEGMLQIDAQAKTLDLAASANLVKMYAAR Batde5 VELNALAALKIIKHCKDGPAT-CSGQLLGIDQITNAFYQTQMLCCLRALNSVGWYQSTYMGTYW-NQAIID-AQYNYQKNSP-HAVMIIYDPSGTS-QGNLSLKALRLSDTFMQVYETRKFSTENILEHKLTPGSVFETIPLKISSSHLLNTALLEVSNQLTPNFDNLELSLEKHLERMVESVEQRSFNKEQIRSQHSQMNADNAAAIAAGPPIH--HEESSFAKVASNEPSRLETLIQLDTYCKQINQFAGPTLTKMFVAK Botbo1 VQLDGLVVMKIVKHGREAPAP-ASGTLVGLDEVSNSFYEERVLRSLKEVGVVGFYQTTTMGAFL-TQSLVE-TQASNFEKLRHGGVVVVHDVTQAS-RGNAALRAFRMTPEFLEAHKKRKFDTQSLIDNRLTFSNILEEVPVVVRSSVLLSAFLSKLTQSLSPTYSHLDLTLSRHMESIIDTLDSRQIARERTKADAAKRRDENAARVAQGPPLP--EEDTRLFKIPP-EPSRLDSMIQLDGYTKSLEASTGSGLVKMYAAQ Botci1 VQVEALVVMKIVKACAATPTT-ATGSIVGMDQITNSFYQSEMIKMLKEVNNVGWYTSANMGNFI-NTSLIE-NQFFYQKEPNERTVALVHDVSRSA-QGALSLRAFRLSPTFMAAYKESKFTTENMQKSKLTYKDILVELPIIVHNSHLLTSFLHQMPVELYPNMESLDLSLERTCDMLLDSIEQRQLTREQAKVTAAKRTAENATRATQKAPLP--EDEERLFKLPT-EPSRLEGMLQVEQYSRQVDGFTASITGKMFAVK Caeel ILLDSLVVMKIVKHVDSESGDACAGVLTGLVEITNCFH--EMLDMLRKFEIVGFYQSHQFGAGF-SHDLVE-SMFDYQ------NVVLIYDPIKTR-QGQLSLRAWRLSTAALDLASKNDWRPELVKAAGLTYQNMFEELPIIIKSSYLNNVLMSELSLA-----RHFDLGLEKSVRAMMANVDTIDKQRHDNMVFSQKRQQENESRVARGPTIP--MDDKRI-KAP--QLQTRNGLLALADFSKTVT---SENITKMFIAE Canalb1 VHISSSVLLSLLRHTSEHPQL-FSGALLGFEDVTHGFYQKDLLENFKKLEFLGWFQSTVSGNFV-TNQLIE-GL--AQQQLINS--FILINNLSSV-GQEVSIKALRLSTGFMNAYVDGKWKSKDLESNKISYLNIFEELNLEISNQKLVDVYLSSLSLK-----DVLNLLTGQLLESLSGQVDQRQYQKEQSKIQQQQRKLENLERAKKGKELD--TEEKTIFKLPN-EPSRYNNMLAIDVLADDILKKCDEELTKSFAIE Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow VQLDGLVVLKIIKHCRESP-DLVNGQLLGLVEVTNSFYQTDMLRLLRAILLVGFYQSTYLGSFL-NTTLIE-TMFDYQREI-EEAVVLIYDPLRTT-QGSISLKAYRLTQAFMDLFKDQGFSADSPKLNGLTHETILEEVPIQIYNTHLANALLLEW---M---FERADMPLEKNLDLLIDAIDQRTLSRYQQSLSMQKRRQENEARIAAGQPVS--EAD---NRAPV-PPSHLDTLLQIGQYCKQVNQFASAAFSKLYVAE Catan2 VQVDALVALKIIKHAKDQPTA-VTGALLGMDEVTQCYYQFEMLKRLRQVNTVGWYHSSPLSNFL-HHTWIA-TQSDFQATITN-SVVLEYDPLASQ-TGALSLRAFRLTEAFIKLYPRSSITSDAVTRAGLLDEGLLEELPVSIRNSHLVSALLYAHNL------PGVDRATAKHAEALLNTLENRVYQREKARIELNRKRQEN----------P--DEAAMSAKLPN-EPPKLDSLLQIDQHAAVVEGFLAPAVLSVELAK Cioin VQIDGLVVLKMVKHCEEDP-ELVQGVLLGLVEVTNCFYQMDMMRSLRHVLHVGWYQSSNHGNFI-NRTFFD-SQFSYQSAI-EESVLLIYDPLKTS-QGSLSLKVFRLTKKMMEMYNSRQFNLDVVKKEGLGFEGMYEEVPVHIKNSPLTSLLTLKL-------------------------------------------------------------------NP---TPERVEYLN------------------------ CocheC53 VQIDALVAIKIATASGKSPSI-ATGSIVGMEEITNSFYSNEMIKFLREVNNVGWYTSTSMGNFV-NLNTIE-NQYFYQSQPNERTVALVYDVSRSS-QGTLNLRAYRLSPSFVAAYKEGKFTTESLQKSGLRYHDILVELPVTIHNSHLLTSLLHQLPSSLFPNYDSLDLSLEKTCDLLLESIEQRSLAREQAKITAQKRKAENAARTASKSLLP--EDEQRLFKLPQ-EPSRLETLLQVEQYSRQVDGFTAGVTSKMFAVK Coere1 VKVDPLAILKIIKHARESPTS-VNGQLLGLEEVTNAFYQVEMMQCLREVSSVGWYQSTRLGDFM-QQPLLD-VQASYQSSASSSSVVLIHDTAKSEQAGNLSLRAFRLSPTYLELAKSGKFTTKELANKGLTYGNILEELPIHVETSSLSKVLLHELQWPLVPSRNALDLSLLRQLETVGELIDKRGEAKEKNRRQQQRRTQSNAARVARGKPEP--ELTDKMFKTLP-EPSRLDALLNLNLLTKGVTQSRGPALTKMYLAQ Conco1 VQLDGLAALKIMKHCRENPNH-ASGQLLGLDEISTAFYTQDMMRNLREVNTVGWYTSTYLGNFL-TQNLVD-TQYSYQKSLGGKCVVIVHDLTRSS-MGNASFRAFRLSQNFMEVYQENKFTTESLQQNNLGFSNILEELPISFHNSHLINAMMHEIQ--LSPNFNILELNIEKSLSQLIESVDQRTVARESARIQQQQKKSENISREAKGAPLP--VETSQMSKLPQ-EPPRLDSLLQTSTYCQQLNQFTCPTIAKMYSAK Conpu1 VQIDGLVMSKIMKHSRDTTSS-AHGLLTGLDEVSNSFYQSSMLRALKEVNVVGFYQTTTLGALF-SQSLID-TQAIYQDRLRHGGVIVVHDVSQTA-RGNPSFRAFKLSASFMDAYRKANFSTTSLINHRLTFSAILEEIPVRVRTNALLSSFLGTLSTSLDRSWRVLDVGTTRHLEQLGDAIDTRQIGREKQKAETAKRREENAARAAQGAPLP--EEDSRLFKIPQ-EPSRLESMLRMDGLAASLEGSASTSLVKMYGAK Copci VQLDGMAVTKIIKHAREASTT-AHGLLLGLDEISNSFHQAAMLRSLKEVSVVGFYQATTLGAFF-NQTLLD-TQAIHQDKLRHGGIVIVHDLSQTA-RGNASFRAFRLTAAFLDAYKRSNFSTPSLISHRLTFSSILEEVPLKIRTNPLLSSFLGTLTETLAPSFSVLDLGTTRNLEQIVEALESRQIARERAKAEAAKRKEENQVRIAQGAPLP--EEDSRMFKIPP-EPSRLESLLQIDGYAKNLESTASMGLVKMYGAK Croqu1 VKVDSLAVMKIIKHARE-PAA---GQLLGLDNVSDAFYTSSILPRLSALNIVGFYCSTINGQHLATPGFIE-TLISIQKTLAGKGLAIVYDLASST-QGTVQLKAYRLSPNFVETYRSGKFDSQTLADHKLTVTNILQEIPLVIQSSALLTAFLATLLTP-LPSYAPLGLPISDTLLAVISAIESRQLARDRTKLESSKRKADNEIRAQQGPPIP--PSA-AALQ----EPSRLETMCGVDGAAKKLSETSGLGIVRAFGAK CryneH991 VSLSSLVFLKMMKHSTDSPPTELSGVLLGLDEVEDCYYSARLLSRLGTVSPVGIYLSTHNGGFA-TRVSIE-------EKAAGRAILVIHDASRSN-GGDLSVKAYRLADGAREAAKLGRWDGQVLTEQGITASTLLTSIPITVSSPSLVNAFISTLNTPLPPSFAPLINPLTTYLQNTLDALTTRQIAREKTKHEQKDREEENARRRKMGSEFPSIPEET---K----EPSRLEMVCTVEGIAKGMAAEAGKGLVRAYL-- Crypa2 VQVEALVVMKITKHSSTSPTT-ATGSLVGMDEVTNTFYQNEMIRHLKEVNNVGWYTSATMGNFI-NLGFIE-NQYHYQRE-NNNVVALVHDVSRSS-QGSLSLRAFRLSSTFMAAYKEGKFTTDSLQKSKLTYRDILLELPVNIHNSHLLTSFLHQLPVPPYPSLDTLDLSLEKTCDLLLDSVEQRQLAREQTKITATKRKAENASRAAAKPLLP--EDEQRLFKLPP-EPSRLEGMLQVEQYSRQLDGFTANISAKMFAVR Debha1 IDVESSVVLSLIRHTSEHPSL-YSGALLGFEDITHAFYQQDILDSLKKLGFQGWFQSTVSGNFV-TTQLVD-AL--VQQQLTNK--FILIHNMASI-GKELDLKAIRLSESFVRTYLDGKWKSKDLENHKLSFLNIFDEIPIRIRNQHLVNLYLASSTND-----DILNLSTAQLLESLYGQVDQRQHQKEQSKIMQQQRKLDNLERAKIGKELD--TEEQSLFKLPT-EPSRYNNMLAIDVLADDILKRCDEDLTKSFAIE Dekbr2 VEINASVALKLAQIGQKHPGT-SSGPLYGFDNISHIIFQADFQTKLNDSKLLGWFMTATKGKQN-RQTVVE-SMLRLQKKMIEEVIFVIYDPSKST-DSLLSLQVLKLSDAFVKTWSEARFAARNLIDNRLTYRNIFEEVPSKIRNSNLTDLKIQELDVN-------LELTTTQTSEQLIDAIDQRSLSRELTKINQLRAKQEHLDHLKTDPELD-----KEHYKLPQ-VPSKYEHVVLLSSLCNNVSTTGSVEHAKTTGIQ Dicdi VQIDGLVVLKIIKQCKEYP-ELVPGQLLGLDEVSNCFYQLEMMRFLREVNTVGWYTPTYLNSFF-NESVIE-TQYNYQATINQKCVVIVYDPIKTS-QGTLSLKCYRLTQSFMELFKDQSFSRERLDQANLSFNDIFEQIPIKIHNSQLINALLYEF---LTNSFDRLNISLEKVVEGMTDCLEQRNIQTQ---KTNQQKFLE--------QKVD--EDESMI-KPLN-PPSKLTSLLQINNYTDQIHSFSGNSLTKLSLLK Dmel VQCDGLAVMKMVKHCHEEM-DLAQGALLGLVEITNCFYQLTVMRRLRRVLHVGWYQSSDVGNSL-SMALLE-SQYHYQTSI-EESVVVVYDTQKSS-RGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYENLFAEIPIVIKNSPLTNIMMSEL---KGHNF--LDLGLENQMRSLIERVDQQVVFKQDTEKHRAKLAAENAVRTSKGPTVP--EEE----RPMT-APNRLTATIQINTHAQHIAQFCSQSLAKLFITE Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VTIDALVLMRIIKHCNES-----TGHILGFQNLSHCYYSSSMLDALVDFNVFGLYRAIQFGEVV-SFEVID----DFL------ATMITYDPIRSQ-HGAAALRAFRISKEFLSLSAAKDIRSEDYAKAGLTFDNIFEEIPLTIRNSALVSAFLFDM--------SQLSLPFERVIDALADRIN---GGRY------NKKAVTEESRL--------------------------NALLQIESYCKQVSQFAGQALPKLFLAK Fomme1 VQLDALVVSKIIKHGSEAGSTPALGLLIGIDEISNSFYQSSMLRSLKEVSIVGFYQSNTLGAFF-KQSLLE-LQAIHQEKLRHGGIVVVHDVMQAS-QGNPAFHAFRLTKTFLHAFRTGRFNTQSLVEHNLTFSSIVEEIPLRIRTNPLADAFLSTLTTPVPPSFSALDLDLTSNLSSVLDALDQRQIAREKLKAEAQKRREENALRVSQGAPLP--EDDSRLFKIPP-DPSRLESTLQIDAYSKSLAQGASVNLVKMYSAN Fusgr1 VQVEALVIMKIAKHCSSAPSV-ATGAIVGMEEVTNTFYQNEMIRHLKEVNNVGWYTSATMGNFV-NMNFVE-NQFHYQSA-NENAVALVYDASKSS-QGNLTFRAFRLSPAFMSAYKEGKFTTEILQKSKLTFKDILAEVSVSVHNSHLLTTFLHQIPSALYPSIDNLDLALEKTCDLLLESIEQRQLGREQTKITQAKRKAENAQRAAAKEPLP--EDEQRLFKLPQ-EPSRLEGMLQVEQYSKQVDGFTANVSAKMFAVR Galma1 VQLDGLVVTKIIKHAREASST-AHGLLLGLDEVSNSFHQAAMLRSLKEVSVIGFYQATTLGAFF-NQTLVD-TQAIHQDKLRHGGIVIVHDLSQTA-RGNASFRAYRLTAAFLDAYKKSNFSTSSLMSHRLTFSSILEEVPLKIRTNALLSAFLGTMTDSIGPSFSVLDLGVTRNLEQIVEAVDSRQIARERAKAENAKRKEENQTRVAQGAPLP--EEDSRLFKIPA-EPSRLESLLQIDAYGKSLAGVASTGLVKMYAAH Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 VQIDGLVVLKIIKHCREFPNP-VTGQLLGLDEVTNCFYQVDMMRCLREVNTVGWYQSTYLGSFV-THKLIE-TQYNYQQTFNNKSVVIVHDVSRST-HGNLSLRAFRFSQAFMEAQKESKFTTESLIKNKLTFSNIFEELPITVKNSHLMTALLHSLD--LSPNFDTLELSIEKI--------------------------------------------------------------------------------------- Hisca1 VQVEALVVMKIIKHSSQAPTI-ATGSLVGMDQVTNCFYQAEMIKMLREVNNVGWYTSANMGNFV-NLNVIE-NQYYYQKELNERTVALVHDISRSS-QGALALRAFRLSPQFMAAFKDNKFTSEQLQKSNLRYQDIFVELPVQIHNSHLLTSYLHQLPTPLTPNFDSLSLSLEKNCDLLLESIEQRSLAREQAKIAQAKRKAENATRTQLKPLLP--EDEQRLFKLPQ-EPSRLETLLQVEQYSRQIDGFVAATTGKMFAVK Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 VQLDGMVVTKIIKHAREASTT-AHGLLLGLDEISNSFHQASMLRSLKEVSVVGFYQATTLGAFF-NQSLVD-TQAIHQEKLRHGGIVIVHDLSQTA-RGNASFRAYRLTAAFLDAYKKSNFSTTSLISHRLTFSSILEEVPLKIRTNPLLSSFLGTLTESLGASFSVLDLGVTRNLEQIVEAVDCRQIARERGKAENAKRKEENQGRVAQGAPLP--EEDTRLFKIPP-EPSRLESLLQIDAYGKSLARTASTGLVKMYATK Lenti61 VQLDAIVVSKIIKHAREAGSS-AHGLLLGLDEVSNSFYQGSMLRSLKEVSVIGFYQGMTLGSFF-NQTLVD-TQAIHQEKLRHGGVVIVHDISQTT-RGNASFRAFRLTKAFLDAYKRNNFSTSSLIDHRLTFSRILEEMPLKIRTNALVSSFLGALTEGIPPSYSRLNLGTPRNLELITEALDQRQIAREKARADTAKRKEENASRVAAGPPLP--EEDSRLFKIPP-EPSRLESMLRIDAYGKSLEETASTGLVKMYASK Malgl1 VQVDGMVLMKIVKHCKDNAVN-GSGALLGMDEVTNAFYMGEMLRLLHQVNPVGLYQGAFLGPFL-NTAVVDGLNTLSLLMEREGAVMLVHDYAQLA-QGNTVLKAFRLSSSFIDAYRKGKFSSQSLIEHRLTFSNVLIEIPVHIRNSALLDAMLTTLTTEVPPNYMDLNLALVSTMESTLDAAEARQIAREKARADAARRKAENATRESAGAPLP--LDEHKLFKIPA-EPNRLESLLQLDSAAQRLSETAAVGAVQLDAAR Mellp23 VKLDSLAVMKIIKHARE-IAS---GQLLGLDNISDAF-------------------------------------------------------------------------------KMGK---------------------------------------------------------------------------------------------------------------------------------------------- Mnele VEITSQVIMKITRHCHHEPHV---GVLLGLIEVTHCFYMLEMERSLRQVQQVGFYQSTYLNTHC-DRNFLD-SVFDYLEEMNE-AIALIYDPLKTK-LGNLSIRAFKLSAPAFKLYEDKEFTAEMLRENSLTYENLFVEIPVVIKNSSLTNVLLCELDS-VQDNTSFFTLPLEKSMQLLLGGLDQRNVYKQQTAIMKQDQKEKNDARVKDGKPLP--EEDSKIFKDFA-PVGRLESLLRIASHCDMIEDHVRSGIGKLYLAD Monbr VTVDALVVMKIIKHARENPHEPVRGPLLGLSEVTNCFYQVQMMRWLREVMNVGWYQAADMGTFF-DEDVAA-VQFQHQRHM-AESVVLIYDPVLTL-QGTLSLSAFRLSNKAMELFSTDSFNPKAVREAGLTYRTVFEKVPVTIRASSMARLLIPEL---QSEIFDRMDLNMSRNIKLLMEGIDHRNATKAKASLDAEARRAENEQLRAKGPEKS--EAE---HKTPT-PPSRLGSLLQINTFCKQVSDFSGQSFGKLYIAK Morel2 VQLDAMVVLKIVKHCRESPAT-VTGQLMGLDEVTHSFYQVQMMRCLREVNSVGWYQSTNMGNFM-NQSLIE-HQFEFQQALS-KSVLIIHDVARSS-MGNINLRALRLTPAFMKLYKEKKFTTEALTKAKLTFSNIFEELPITIRNTALLTALLYELE--LAPSFDVLDLSVAKNLENLMDTIDQRSVERENKKKAALNRKTENARRAQSGAPLA--NEDDAMFKTPA-EPSRLDHLLQIDNYCKQINEFAGPTLGKLFAVG Mucci2 VQLDGLVVLKIIKHCRESPND-VTGQLLGLDEVTNCFYQLDMMRCLRAVNTVGWYRSAHLGNFV-DLSLIE-TQYSYQNSLSAQSVVLIHDVSKSSAQGNLNLRAFRLTETFMKAYEAKKFTTESLAQAKLSFSNIFEELPVEIHNSHYVTMMLHNIEMPLAPNFDVLDLEMQKNLQYLLDCADQRSVAREQAKMQATKRKQENAQRIEKGKPLP--EDENTLFKLPA-EPSRLDSMIQMHNFTKQINQFAGPSLARLYSIQ Mydma VQIEGLVALKIVKHCHEEPGEIAQGDLLGLLEVTNCFYQIDMMRKLREVFHVGWYQSTCLGSFL-NRNFVE-SQFHYQRSI-EESVVLVYDPLQTH-QGMLSFKAYRLSQKMLDLYAEKNFTPEMLIKENVDFTNILEEVPVTIKTSNLVNTLICEI---EKEEF--LSLALEKNVHLLIEGADQRNVARQQ-------------------QQID---------KQRR-VINYLLYLF-------------------CSLF- Neucr2 VQVEALVVMKIVKHCSTSPTV-ATGSIVGMDEVTNSFYQNEMIRHLKEVNNVGWYTSATMGNFI-NMSFIE-NQYHYQKE-NEKTVALVHDVSRSS-QGALSLRAFKLSPEFMTAYKEAKFTTESLRNSKLTYKDIFVELPVNVHNSHLLTSFLHQIPAPAHPGFESLDLSLEKTCDLLLDSIEQRQLTREQFKITQAKRKAENAARLAAKSPLP--EDEQRLFKLPQ-EPSRLEGMLQVDQYARQVDAFTANITAKMFAVR Orpsp11 IELDSLVVLQIVKHCQESPAT-VTGQILGIDKITYSFYQLRMLTNLRNMNTVGWYRTAD-NNLW-DATFIE-NQYNYQAAIQQ-SVVIVYDPVRSS-QGNINLHAYRLTDEFMEVYKEKEFDVKTYMNKKLNSSKIFENIPIKIKNNIYDDCLISQYDE-PSPNFEALDLDLIKKLEILNLEIDYKLVQSELSKIKAQMKIKENRELANQGPPKY--TEEPNLEKLYSNGSFELDIPLRMEMHCKQIKQFAGPSMTKMFMVK Pench1 VQVEALVVMKIIKHCSQTPTT-ATGAIVGMDEITNTFYSAEMIRMLREVNSVGWYTSANMGNFV-NMNVIE-NQFYYQSQLNERTVALVHDVSRSA-QGSLSLRAFRLSSKFMTAFKENKFTSEDLQKSNLRHPDIFEELPVKLHNSHLITSFIHQLQTPLTPNLDNLSLNLEKNCDLLLDSIEQRVLGREQQKINAAKRAQENATRATLNPLLP--EDEQRLFKLPA-EPSRLESMLQVDQYARQVDSFVSSSTGKMFAVK Phybl2 VQIDGLVVLKIIKHCRESPTD-VTGQLLGLDEVTNCFYQLDMMRCLRAVNTVGWYRSAHLGNFV-DANLIE-TQYSYQNSLSANSVVIIHDVSKSAAQSNLSLRAFRLQDAFMKAYEAKKFTTESLAQAKLSFSNIFEELPVKVHNSHLVTLMLHNLEMPLAPNFDVLDLEMQKNLEYLLDCSDQRSMAREQTKMQTTKRKQENVHRAQQGPLLP--EDENTLFKLPA-EPSRLESMIQMHNFTKQLNQFAGPSLARLYSIQ Picst3 INVESSVLLSLIRHTSENPSL-FSGALLGFEDVTHAYYQQEILESLKKLEFQGWFQSTVSGNFV-TTQLIE-GL--AQQQLTNK--FILIHNMASV-GKEVELKAFRLSEGFIGAYIDGKWKSKDLEANKLTYLNIFDELPINIHNQHLVNLYLAGLDNE-----DVLNLSTAQLLESLYSQVDQRQHQKEVSKITQQQRKLENLERAKRGKELD--TEERGIFKLPS-EPSRYNNMLAIDVLADDILKKCDEELTKSFAIE Plicr1 VQLDGLVVTKILKHSREASTT-AHGLLLGLDEISNSFYQASMLRSLKEVSVVGFYQATTLGAFF-NQTLVE-TQAIHQDKLRHGGVVLVHDLSKTT-RGNASFRAFRLTSEFLDAWKRSSFSTQSLVNHRLTYSSILEEIPLKIRTNPLLSSFLGSLTEPLPPSFANLDLGLTRNLEQIVEAVDSRQIARERARADGARRKEENAGRVAQGAPLP--EEDSRLFKIPA-EPNRLESMLQIDAYAKSLGGTASTGLVKMYAAK Polpo VQIDGIVVMKIIKNCKEYP-ELVPGQLLGIDEVSSCFYQLEMMRFLREVNTVGWYTPTYLNSFF-NESVIE-TQYKYQSAINQKCVLLVYDPIKTA-QGTLSLRCYRLTTTFMELFRNHPYSRERMDNAALSFADIFEQIPIRIHNAQLINALLYELR------FDRLNIGLEKVVEGMTDCVDQRQYQQQQFIRNSQKKTLE--------QKVE--EEESMVNKPLH-APSKVTSLLQINNYCDQLSSFCGGSLTKLSLYR Pucgr2 LKVDSLAVMKIIKHARE-PAS---GQLLGIDNVSDAFYTASILPRLSALNVVGFYCSTVNGQHCATPGFIE-TLISMQKIAGGKGVALVYDLASAT-EGTVHLKAYRLSKEFIETYKSGKFDSQNLANHKLTTSNFLQEIPLNIQSSALLTAFLATLIAPFLPSYSPLGTPLSESLAATIASIDIRQLARDRARLESNKRKAENETRAQQGPPLP--PSA-ASLK----EPSRLESMCGVDSAAKKLTESSGLNVVRAFGAK Punst1 AQLDGLVVSKIIKHASEASAT---GLLLGLDEVSNSFYQGSMLRSLKEVSVVGFYQATTMGAFY-TQTLME-TQAIYQEKLRHGGVVIVHDITQST-KGNASFKAFKLSKAFIDAHKRKNFSSASLANHRLTFSSILQEIPLKIRTNALLSSFISRLSQPVPSSYQVLSLDIRQPLSRLIDALDSRQIAREKAKAEGQKRRDENAVRQAQGQPLP--EADQRLVKVPP-EPSRLESMLQVDAYAKTLEGGASAGLVKMYGTK Rhior3 VQLDGLVVLKIIKHCRESPND-VTGQLLGLDEVTNCFYQLDMMRCLRAVNTVGWYRSAHLGNFV-DLSLIE-TQYSYQNSLSAQSVVLIHDVSKSAAQGNLSIRAFRLTDAFMKAYEAKKFTTESLAQAKLSFSNIFEELPVQIHNSYYVTMMLHNIEMPLAPNFDVLDLEMQKNLQYLLDCTEKKAVAREQAKMQSTARKQENAERAEKGEPLP--EDENTLFKLPP-EPSRLDSMIQMHNFTKQLNQFAGPSLTRLYSIQ Rhoto1 VRVDGLALMKIIKHSRESPAV---GQLFGIDEVSNAFYTQQLVSRMSDLSVVGFYTSTNNGQVLATGGFIE-ALVGAQANKSGKGIALVYDIASAT-QGAVGLKAYRLSQAFIDAYRSGKFDTASLIQHKLVPTNILEELPVTVHSSALLTAFLSTLTAP-TPTFSPLSLSLTQPLQHLLSSLEARQLARDRTRLEAAKRRLENEQRAREGPPLP--MTDRAGLK----EPSRLETMCAVEGAAKSLAEATGTAIARAYGAK Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro VVVDALVVAKVAKFARDSPGNKVMGSLLGMQEVTDCFFKDNMLNAMRAVDEVGLFQICDARSLF-DQTLIS-NLLEYQSTMSA-AVILAYDPTLVE-EDTLSVRAFRLSDVMLKFLGDQPLSPDELKVDNLTSSDIFEEIPMTLHTSVLARAAIPELISQ---SFEELDMSLEDNISAMMNCIDKDSAGRNQDIAA-REFKDKNTRPPTMRQNFP--DEH---------TPTGVQPLLQISAYCDHLAKFSSQGISTLYLTE Schco3 VQLDGMVVSKIMKHAAESTPN-ANGLLLGLDEVSNSFYQASMIRSLKEVGVVGFYQATTMGAFF-NQTLIE-TQVANQERLRHGGVVVVHDLTQAA-RGVAAFRAFRLTPAFLDAYKSSNFSSSGLATRRLTFSTILEEIPLKIRTNPLLSAFVNSLSKSLPPSFRALDLGLTRNLEQIIDTVDSRQIAREKAKADSAKRKEENATRVAQGPPLP--EEDSRIFKIPQ-EPSRLDSMLQLDSYGNSLGGTSRTGLVKMYGAK Schpo1 VELESLLVMNIIKHCRDSPNM-GTGQLVGIDQVSSSFHTEAMLNRLQYIGHVGWYLGAYVSSFL-SSPFFVETQYAYQKA----SIAFLYDLSQSS-NGTLYMRAYQLTPEFMAAHEEKTWTASSLNSHNLTPSNVIRELPIVIHNSHLATCLLHSLSEPLTETFSNFEVSYRKNIELLLESTDQRQLAREQAKIQQAKRKAENANRAAENQPLP--LDDKRIFKLPA-EPRLLDSLLQIMK-STQIDEQSSAFLSKLAGVR Sorma VQVEALVVMKIVKHCSTSPTV-ATGSIVGMDEVTNTFYQNEMIRHLKEVNNVGWYTSATMGNFI-NMSFIE-NQYHYQKD-NEKTVALVHDVSRSS-QGALSLRAFKLSPEFMTAYKEAKFSTESLRASKLTYKDIFVELPVNVHNSHLLTSFLHQIPA-AHPGFESLDLSLEKTCDLLLDSIEQRQLTREQFKITQAKRKAENAARLAAKAPLP--EDEQRLFKLPQ-EPSRLEGMLQVDQYARQVDAFTANITAKMFAVR Sphar -------------------------------EVTNCFYQIEMMRNLRDVNTVGWYQSTFMGSFI-SPSMIE-TQFAYQENIH-KSIMIVYDPHRSG-QGVLSLKAFRMSASFFKLYKSREFNTAAIKKHGLKYEQIFEEIPIKVHNSALSQALLYELD--LPDMYDRLDLTLEKELECMLDCAD---ALRKDLQFQSQKRRAENEIRKQQGEVLP--VDDQDAIK-PVPVPPLFESMVQMNTYCGQINELSNQASNKLHFCK Spipu1 VQLDALVVLKILKHCREYPVT-ATGQLLGIDEVTNCFYQLQMLRCLRKLNTVGWYQSTYLGSFW-NQSLIE-TQYNYQKTFA-QSVVIVYDPTRTT-QGNLCLRALRLCDGFMELYQNRKFTMESLIHNKLTPTSIFQSLPIKIRNSHLLTALLHELDEQFSPNLDKLELGLEKHLEYLGETVEQRNLQKEQQRLQQSKRRLENSSRAAQGPPAY--TEEQTLTKILANEPSRLESLIQIDTYCKQVTQFAGPGLTKMFMTK Sporo1 VRVDGLALMKIIKHSREAPAV---GQLLGIDEVSNAFYSTQLLSRMNDLSLVGFYTSTNNGQILATGGFLD-ALVGAQQNKSGKGIALVYDIASAA-QGAVGLKAYRLTSNFVEAYRAGKFDTAGLIENKLVPSNILEEVPVTIHSNALLTAFLSTLTAS-TPSFSALSLPLTQPLQHLLTALDSRQLARDRARLESAKRRQENEQRAREGPPLP--PSDRAGLK----EPSRLETMCAVEGAAKSLSEATGTGVVRAYGAK Stehi1 VQLDGMVVSKIIKHASDSSSI-VHGLLLGLDEISNSFYQTSMLRSLKEVSVVGFYQSTTMGAFF-KQALID-TQAIHQDKLRHGGVVLVHDVSQTA-RGNAAFRAFRLSKAFLDAYKRRNFSSQSLINHQLTFSSILEEIPLTVRTNPLLSAFLGTLSTPLPPTFSTLDLGTSKNLELVIESMDSRQIGREKARAEQAKRREENAQRVAQGVPLP--EDDSRMFKIPP-EPSRLESTLQMDAYAKTLEGTASANLVKMYAAK Tapde11 VKIDALVVLKIAKHCRESPNPGTTGQLLGLDEVTNCFHMNHMLHCLRDVNVVGWYQSAYLGTFL-NQQLTE-TQFAYQKQLNDRSIVLIHDICTSS-AGNLDLKAYRLTPSFLAAQREGKFTMATMKKNRITHRDILEELPIELQNSHLATALLQELKVIGSENYSSLDLSLEKNLDFLLESVDARQVGREHVR-----RKAENANRIANGAP-------NDPITLPN-EPNRLESLLQIDKYCGQIEEHSGTACSKLYFAS Thetr VQMDALAALKIIRHCQESPRL-AGGQLLGLDEVTNCFFVNKTMHFLKLVNAVGWYTTSIIGSNL-TQSII--TQFDYQTA----AVLIVYDPLRTR-KGSVCLRAFQLTEAFMTLFKGKKFSADDLLDSDLSFRDIYTERPIRIYNSPLVNAFLLEMQDS----FDRFDLELEKNMEYLLEAIDKNRVAHRDEQ---KRRRAENEARRADGAPIP--ETDKRFGSLPD-VSSRLEALLNVNNYALQLRSYVHQSFTRVYATE Treme1 VRMGGLVLLKIIKHSTDSPTTALSGVLLGLDEVEDCFYSARLIDYLRASSPVGIYLSTHNGGFV-TRSTIE-------ERVSGRAVLVIHDASRAN-GRDLNLKAWRLSDGAKAAAQKGKWDGQSLVENKLTASTLLEPLPLTISSPQLISAFLTSLSTPLSKNFETLSNPLPAYLSDTLDSLTVRQQARDRAKLEAKDREEENLRRKKAGGELP--PVNSAAGK----DPNRLELLCMVDGLAGSMAGEAARGLVRCYL-- Trire2 VQIDALVILKIARHCSSTPTV-ATGSLVGMDEITNTFYQAEMIRHLKEVNNVGWYTSATMGNFV-TMPFIE-NQFYYQKD-NDKTVALVYDTSRSS-QGTLALKAYRLTNLFMSVYKEGKFTTESLQKSKLSFRDILQEYPLAVHNSHLLTSFLHQLPSPLYPSIDNLDLSLEKTCDLLLESIEQRQLAREQTKITQAKRKAENAQRTLAKPLLP--EDEQRLFKLPT-EPSRLEGMLQVEQYSKQVDGFTANISSKMFAVR Umbra1 VQLDGLVVLKIIKHCRESPVD-VTGQLLGLDEVTNCFYQLDMMRCLREVNTVGWYRSAHLGNFM-DLNLID-TQYNYQNSLSAQSVVIIHDVSKSAAQGNLSLRAFRLTEAFMKAYEKKTFTTESMIKNKLTLSNIFDELPIQVHNSHLVTALLHDLDSPLAPNLEVLDLEMQKNLENLLDCADQRSVAREQTKIQATKRKQENAQRAQNGSLLP--EDENSLFKLPT-EPSRLESMLQIHNFTKQLNQFAGPSLGRLYSVQ Ustma22 VRLDGLALTKIVKHCRDAPAS-ASGALLGMDEISNVFYTSDMVRLLRDVNPVGLYQGCFLGAFL-NSSVIDGLAAITGLVERDGGVLIVHDLAQSA-QGNTSVKAYRLSPSFVDAHKKGKFHTQSLIDHKLTFSNILIEIPVSLRNTALLDAFLSSISTPLAPSYTSLNLALASSLESTLEIMDARQLAREKAKADAARKKAENAAREAQGAPLP--IEDNRLFKIPA-EPSRLEATLQIDSSARRLAETAALGVIQLNAAK Walse1 IEVDALALSKIAKHSSEN----ATGICLGLDQVTNVFYNSKMCRNLSDVQPVGIYIAIEFGATI-NEILLS-----YASALGKNGFVLLYDTSSAS-KGNLNLRAYKIQENFIQALRTNQFSEKGIIENQLTFSDILQEYPIELKSSSLTKAYLESLSTPLSKNSKILQLDLQANIDNLVESLDNRHLLRERAKVEQQKVQQQ---RQSQNAPLS--ESEQRQFKLPA-EPSKLPSLVQLDGISQRLSDNALSSISMTHPDG Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2421.fasta_al_trimmed; alignment length = 297] Allma1 SLAA--ALSFDSTKP-VDLDPESDDLSD---RSHYAAVGKSALRAAYAGRSVSRK--DA-SDDDD-------DDEEESSDTED-MSDYEPGRSD-DSSPAPREENLTRKALDTA--DAEKGAHELWDALLDLRIRLQKVIAIANRFPQT------VAGSVTTAMDETWAVAEF--QRADALEKWHEKVSATAKAINTS-LAHQLESVL-SD-DRLVKRTQIKRSIF-DDTDWYSVLLKEVIDRKKR-AVDTRASKGRKLRFAPH-EKLQHFMAP-MPEEMVEELFSSLFGVGKLRLF Ashgo11 TLAD--QITENKSKV-PDFDIEDS----ALQAAHYVQVGRSKLRN-YSGSKGSREALSS-GEEDGSESDRRGSDSD--SDSDSEQSADESARSDSDSGVRLETQQAMGKLNAAVQNDALKGYARFFEGAIDVRIKLQKAIAAANQLPELLESTCKVAGKCAELIDALAECHDL--DRGAVLHMWSSKVAATSKAINQP-ANVQVDNQL-ADMPRLVKRTQLNRYIF-DDEDFYRVLLNDLVDKKKK-NVDTKASKGRKLNYSVQ-EPIANYEAP---DEQIDEFFAGLLGQD-LRIF Aspfu1 TLAE--RLAEEDPTP-KDFDPEDGN--EA-GREHYQAVGKARLRRQYAGSKISREALAE-SDDDEDEDASE-AKDSKRGSEDDDQEGDED-GDD-DEDMSSDQKTIAATISQAAKADAAKGRAATFDALLNARIKLQKGLTAINRLSEAIKSAESLWSTLEDLTDSLWKMTDL--ERRTVLDKWSLKVRGSTASSQQT-ISAVIDAQVASE-DRAAKRRRHSS-VY-DDTVFYQSLLRDLVEQRKR-DVDTRASKGRKMRFDVH-EKLQNFMAP---ITAREEFFASLLGKVGLRLF Aurde31 SLTQ--QLAEDSAAP-KEFDAEDQDLQP--AREHYVDVGHSSLR-KYDAVKVSRQQLDS-DDDEDEE-----IDRENESASEGDDDDDDE--EE-EDE---ETAAAAAALQKTRQADIAKGKASVWDALIDTRIRLQKTIQATDKLPATLARFFELSNSLFEAVSEATHLSQL--NLLSTLTKWSNKIQAVTANATRN-ILDVIDDTL---------------GVY-DDTDFYQSLLRDVIEARKK-VVDTKASKGRKIRYTVH-EKLQHFMVP-IPDEQIDELFASLLGKDGFRLF Batde5 TLGE--RIAEANPRP-YDFDPENNNESEA-ARNHYASVTRSSLRDQYLGKRVTRKAL----EQEESNEDSND------ELGETQSAESQTDGFE-DESLQKDQGKMMKAMTESAQADVEKGKHGLWDSLLDIRIRIQKAVDLANQMPQQVKETSALLDDLTTLIQHIWDVLAP-FDRDETINKWNNKVQAASKALDQS-VVSQIQQIS-HD-DRLVKRTHLIREIF-DDGDYYQQLLKELIESRGKKAIDTKASKGRKVRYHVH-EKIQNFMAS-EPDEMASELFSSLFGRDGFKIL Botbo1 TLAE--QIAQQDAPP-LDFDPEDDSGDEA-ARSHYVDVGPSAIR-KYEGVKSSRNQIDD-DEEEDDEDEQF-DDASDHSEDSFEDDEDD--------------SELTSTLKRTRDEDRLKGQASLWDTLLDARIRLQKSVTAANRLPKAASRLLELSDNLFDLLKDATHFVAL--EVLTTLHKWSLKINSVAREGAKS-AVELVEEAM-GE-GKVVGRTRVRREIF-DDTDLYQQLLRDVIDSRKK-AVDTKASKGRKLRYEVH-EKLQNFMVP-VPEEQIDELFASLLGKAGLRVF Botci1 NLAK--QIKEEDPVP-KDFDPEDGSESGA-GTEHYVQVGKSKLRKPYAGSRVTREQLNG-DDEGDDMEVDSDS-GEEGENSDEPDQSGDE--SD-EESMGEEQKTVVATISQAAKADADKGNAKAFDSLLNVRIRLQKALVATNSLANPFQAAEELWNTIDGLSSAIWEMQAS--ERQTVLEKWSSKVRATTNAPQQS-ITSLLQDTLSSS--HLISRTKVPRNIY-DDADFYQLLLKELLDQRRK-NVDTKASKGRKMKFTVH-EKLQNFMAP---ESARDRFFATLLGRAGLMLF Caeel GLLD--DISKTPATELPDLEDDN-------SQSALKSLKSTGNRQKYAGSAVSRKELSEISGLQNFDKSESEEDED--DNFDEEEE-NEDD----EED--------MTTLSLK-DEKADKAASLVWDDLLYSNIRLHALLNTANQLPKSMESAMELMKNAMELVKSLAKLQKI--DRATTLTKWYNRTKILNSVFEKGSILGQINKVL-AD-EKLLKKVRTNRETF-DDSDFYQILLKQMLEARKKRDVSQLSSKDRRLKYEPI-ARLINF------HESRNELFKSLFS------- Canalb1 SLSE--QISS-TPKT--DYDIED---SEGLRNEHYVESSKSKLRQQYVGNVTSRSKLDD-EDDKQPTEASSGEELD--SAEEEEES-EDVADDDEDDQMSKERSHIVNRLSQSATNDALKGYSKTFEKIIDVRLKFQKSVTSSNMLPELVTKAKKLLDHLFTLFAKYSETSAA--DRNQILTKWSAKVANSSKTINQS-FEQQVNNNL-SDMDRLIKRTKLNRYIF-DDEDFYRVLLNDLVDKKKN-NVDTKASKGRKLRYHVQ-EPIANFETS---DDQIDEFFASLLGQNGIQLF Cangl LLAD--KLGKNKPVV-GDVDIEDD----ELKKAHYAQVGESKLRKQYVGSVGSREDI-----ENASSGSDSGSDSE--D--DEN---DESESVESESEVEKETRQAMNRISDLTKRDASKGYSKFFENILDTRIKLQKAMNSANVLPKLLEENLSLLNRVINFITDLNETDAL--DRTAVLQKWSAKVSSASKAVNQS-ADAQVENQL-ADTPRLIKRTCLNRYIF-DDGDFYRVLLNDLIDKKKK-NVDTKASKGRKLNYSIQ-EPIANYEAP---DEQIDEFFAGLLGQD-IQIF Capow SLAD--ELARTDPTP-VHEDPE-DQDGEA-SAAHSGGVGSAMLRGLYAGKPVSRRSL-S-DDDDQDEDDQDEQDDDQDEDADEEDEDDDDDDED-DEDMENEEAQSMQALSSTVQSDIVKGQHKLFDSFLETRIRLQSVVTVANRMPQALSSVQTLLDKMLDLTEEYWQMSGT--HFENTIEKWNSKIQLAAKALNQS-VLGQISQVM-TG-DRLIRRSQLKREIF-DDQDLYQQLLRELIERRKR-KVDTKASKGRKLRFQPH-EKLVNFMAP-VDEQARTDLFTSLFGK------ Catan2 GLAA--ALAMDSPAPQADFDPESDDQDD---RSHYVSVGKSALRKQYAGKKVSRKDLEV-DDDDDDDEDESQDESEEESDAESEASDMSEGDSD-SDS--AEADELTRKMLQAAAEDADKGKHDICDSLLDLRIRLQKAVTLANTLPESIAQTRQLSTDLSRAVDQLWATIEF--TRMTALEKWHDKVNATAKAINTS-FSAQVETVL-RD-ERLLKRTHLKRYIY-DDSDFYASLLKDLIDRKKR-KVDTRASKGRKLRFHVH-EKLANYMAP-TPESMMDELFGSLFGVGKLRMF Cioin ---------------------------------------------------------------------------------------------------------------------------DLWEILLESRIKMQKLVSLSNQLP----------DVWLDK---WNSIGQQ--YRNKRLQLWYDKTRVSSNKFERS-TVSQIDHVL-SD-SRLIKRTRLKREIF-DDDDFYHQLLQKLIEQKKK-TVDTKASKGRKVRYHIH-PKLASFMAP-IDHESRNRIIKSLFGK------ CocheC53 --------------T-RDFDPESRSGSDV-GREHYTAVGKSKLRKPYTGRKVDRKTLDS-DSDDQDSEAS----DEEGGGLD-DEEMGSSGDEE-DEEMAAS-KSFTSTIAAGTQSDVAKGEAKTFDTLLNSRIRLQKALISTNSMAAPVEAAEALLNNLTNLSSEIWSIEDT--ERKAILERWSNKTKATTASAQQT-LTEVLDSQLTSS--HLVTRTQVPRAIY-DDADFYGLMLKELLEQRKK-VVDTKASKGRKLRYTVQ-EKLQNFMAP---DRQRDELFSSLFGQAGLMLF Coere1 SLLE--QIADSDPRP-KDFDIENEELSD--KRNHYVNVGKSALRSQYTGSRISRKDLEE-EDMSEDNNTSSESDAPEEAGSDSESDEEGIDMTA-DEALEEGEKALLSSITQTARSDVEKGQHRMWEGSLDARIRVQKLVTAANQLPTQLESTRELLSSIIEL-SAIWKLESL--RRDQSLEKWGNKIQASMKAVNQG-IVHQVNQAM-AS-DRLIERTQLKREIF-DDEDFYKQLLRELIESRKR-KVDTKASKGRKVRYHVL-EKLQNFMPP-VPEDMVNELFSSLLGQQGLRLF Conco1 ------------------FDPEDDSDNSA-GRSHYVNVGKSKLRMNYQGAKTSRKGLES-EEEDEDDEDDED---DEEEGDDDEEEEDEDEDED-DEEFQNQEKELIQNLHKNTVQDSDKGKHKFWENALGIRIQFQKIAQSINQLPSDHQETVDLINQLNTL-DDLWNISSL--YHEGIVDKWHSKVQLGNRSLDQS-ISQQVDQMM-MD-DRLIARTRTNR-IY-DDGDFYQQLLREFIESR---VVDTKASKGRKLRYQVH-EKLENFMVP-VHESKIDELFGSLLGNDGLRIF Conpu1 SLSE--QIAQEEAAP-VDFDPEDEELASA-AREHYLDVGPSALR-KYGGRKASRKELSN-DD-----------DLDR-SSDDDH--------PE-EEERVATSEDLSANLHKTREDDRKKGRAALWDTLLDSRIRLQKSVHAGNRLPASLNKMLVVSEEIMELLRDASNASAL--EFIQTLNKWSSKIQAVASHQLKS-ASQLIDETL-SD-SKVLARTQVYREIF-DDTDFYHQLLRDVIDSRKK-KVDTKASKGRKLRYEVQ-EKVQNFMVP-IPEEQIDELFASVLGKDGFRVF Copci SLAQ--QLAQDDAAP-VDYDPEAGDKEG--AREHYVDVGPSELR-KYEGVRTSRKALEA-EEAEGSEPSDSENDEDDSESSEEDDEEDE---GK-DED--EPSEDLTSALKQAREADKKKGKAALWDTLLDSRIQLQKAVVSANKLPDALLKLSLLADDLTTLLVAACEAAAL--ELVQTLTKWSAKIQAVAKQQLKS-AVQLVDDAL-QD-SGLLSRTRLRREIF-DDTDFYQKMLRDIIDARKK-VVDTKASKGRKIRYHVH-EKIQNFMVP-VPEEQIDELFSSLLGKDGFRVF Croqu1 TFAS--LIKDSSAAP-AELDPEDN-K----NLTEYRPVSPSRLRN-YSGRRVTRKEL--------------TSETE-----DEEDEASEAIPSDGDQV-------LVRQLQASVKADINKGKAATYDRLLGLRIGMQKVLTATNEL-ESKEAALELSSTVGKLLNTCLDAKEL--DLRATVSKWSSKINAAS--VNQN-AMNQLDSLWAMP-DRLVERTRMRRDIF-DDRDFYHSLLKEVVDTNHRAGADPKASKGRKIRYHVH-EKLVSFMVP-IPEEQKDELFASLLGRGSLKLF CryneH991 SLAQ--QLKQNVSVP----DPESDIQRK--GREHYVDVGPSRLRMEYEGVKTGRMKI---DDDD---------EDEEEEDEDEEDDEDEDGESE-DED----ALDPVASLRNSRLKDVEKGQAALFESLITLRITFQKALTASNTVPSKKASILKLNERLFTLGEAYWIKESLGIALVPILNKWSSKIQAASKNGSGG-VVEAIESGINSK---------------------YRALLREVIESRKR-EAERGGSKGRKLRYTVH-EKAQNFVVP-IPEEQVDELFSSLFGGGGLRVF Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 SLAE--KIAE-KPST--EFDIEDN--SDTLKKQHYLAVDKSNIRNEYGGKVTSRGDLSD-EESRSLDEHENSEDSDSGSESEDEDE-SESEDKDEVTKMSNERQHIVNRLSQSASNDAVKGFAKLFDSIIDSRMKVQKSLTNSNVLPKYLNQTLELLDSILALLTDYLETGKQ--DRSSVLSKWSSKIHNAAKAINQS-AEQQVINNL-SDMDRLIKRTKLNRSIF-DDEDFYRVLLNDLVDKKKK-NIDTKASKGRKLRYHIQ-EQIANFEAP---DNQIDEFFASLLGQDSFKLF Dekbr2 TLGE--KITDNKPKN-KDIDIEDSGEEDELETQHYVKVSKSRLH--YSGEHASRSEIS---DDEMQDSNNSTSDDD--SSEDEE---SVNKEEENDEQLNKEKKLTLSRLSISVKQDALKGYMGIFDKVLDARIKFQKALTCSNGLPSKLEDTKTLIRKIELALK---EHTNL--ERKKVLMKWSKRVQNASRTINQN-VYTQLENTL-QDTDRLIRRTRVNRFIF-DDDDFYRVLLNDFVDKKHK-NYERMATKGRKMKYTVQ-EQSRNFEAP---DDQIDQLFASLLGQS-VKLF Dicdi LLSD--EINESENIK-KSIDPESENFGE------------TRLKGDYSGKKSSRKD----NDMEEDDELDQDGDKQDDDNSEDQDKQDDDDKEDDDEDEEEKQPKLVGHTNEA---EMEKAQNALYNEFLTTRILLQKTINCANKLPKKFKETKTLISELYNLLSEIWNIEEQ--NHNQTITKWNNRISVTSKSLNQS-ILSQIQNTL-NDFERLQKRTKLKREIF-DDTDFYQTLLKDLEANNKKK-VNQKASKGRILRYEVF-PKLENFMTP-QS--NIDQLYQNLFGG------ Dmel TVAE--KVSKSDSAEDSDFDVATEEEYD--ARS-------TDFRKRYKGKISSRKEL---DDEDKDDEQEVSSDEDDEEESEEEEEDDDSEEEDHSQE--DDAIKPSDVMSKTNHQEIQKGLARIWERLLELRINTQKFTSKANQLPSVLNEAQELLQQLLSLVKKFGSLQSN--FRNEVLLKWDDRTKLLT-QEDYD-IIKKIGSAL-AN-EALVEKSQTPKHIY-DDSDFYHQQLRELIEYKKK-KVDTRASKGRKLRYVVH-NKLINFMAP---DASKSELYKSLFV------- Enthi SRRE--EIEKGQPKEFGEEEIDK-------EELKMKDSFTVG-KIKWEGKIVNKEDVSK-SNEEEEDNSMSEEDAENSSNEEDEEESNENSNEEGEED--------VETIQKKTNDKED----KLFDTALDIRVKMQGILGDVNSLPEELESLNSLFHRTTEL------LMKV--NRLSIMEKWHSKTTMMNSTNQNG-IVQQVNAIL-KD-ERLFRRSQQLREVF-DDGDFYQQLIK------KK----QIQKKKKRVNTDIVFPKLENFKCP-VE--DRSIFIKNLFK------- Falba LLGE--ALSSSGPAP-TD-DRQDDNIVD--SYAAELSAPTAMTRRSYSGKTSSRKALAE-SDDEEDSSEEEEEEEEEEDEEDDDSSKSSGGSSE-DEDRQLEEEDAASSISIFAEQDAQKGKHTLWNRSLDLRIRLQRCVTLSGRLPSAAAAVRTLLGDIANILRALASVAAI---MEETLEHWSSRAQIATKAIHKS-VPEQVSAVLAAD-DRLVKRLRLDRQLI-DDGDFYASLLQDFLASRRRQGVDQKASKGRRIRHDIH-PKLVNFCVP-TPEARERELFASLHGR------ Fomme1 SLAQ--TLAQDQPAP-VDFDPEDEHANEA-GREHYVDVGLSALRSKYEGVHTSRKQLSD-AGDLSDDVPDSS------SEEEDDEDTDN---------QRTEEHDPSITLKRAREEERTKGKAVIYDRLLDARIRLQKLVSSTNRLPDAANKLLALADELFDFLQESSAFAEL--ELLSTLQKWSNKVLAIASSQMKG-AVQLVDEAL-LE-DKLLERTRNWRDVF-DDTDFYQTLLRDVIDARRS-TVDTRASKGRKLRYEVH-EKLQNFMAP-APEEQIDELFASLLGKGGFRVF Fusgr1 GRAK--EFQDDEPIT-KDYDPEAGSGSEA-GTEHYVSVGKSKLRKSYRGSRVSRDALEE-SASENDSEISSDS-DNEGDGLDAESDENDD--SG-DDE-AQNAKPMMAALS--TQPDVDKGLAKAYDGLLNMRIRLQKALIAANTFEEPYEAAEELLNTISSLTSQIWEMQAE--EREDRLEKWSRKVQSVNEGRNKT-LISALRDQLINP-NRLAKRSRVPRNIY-DDADFYQVLLKELVDQRRK-NVDRKASKGRKMRFTVH-EKMQNFMAP---QGAIDRFFGTLFGRAGLRLF Galma1 SLAE--QIAQEEAAP-VDYDPEDDDAMHG-SREHYVEVGPSSLR-NYEGVRASRKQLEE-SDDAQDDEVEE-DSEEDG-SDEGGDPRSE---NE-EEE--DPIEDVASALKQTRVEDLKKGEAALWDTLLDTRIRMQKSVVSANRLPESISKLLNLSNELFELFSAATEIVTL--ETLQTLSKWSSKIQAVTGQNLKS-VVELIEENL-AD-DKLLARTRVAREIF-DDTDFYQKLLRDIIDARKK-KVDTKASKGRKLRYEVH-EKLQNFMVP-VPEEQIDELFSSLLGKTGFRVF Ganpr1 SRSSKPVNHRNGGVA-LFVDPEVAQGGS--ARKDYVDVAPSTMRKNYKGKKVTRAQLEM-DDSDSDSEVEESSDHT--DESDEDDEDDED-GEDGEDKSDKDNISAPKKKNRSNAMDTTKDPSSLLEALLEYRIVAQRALSLVGRLPQRVVSSIEIRRS---LLDRLRQLASL--DRTSELRKWDQRSTASAKKEQGG-VVERIDAALA---EKLLAKTRVRRNLF-DDAELYSYLLRDLIDRKSRLGVDRKASKGRRLRYKVH-EKLVGFMVP-RG----DWVSRTLFGQDGLKVI Gloin1 SLTA--QLAESNPTP-IDIDPEENEEVEV-GREHYVAVGKSSLRRNYVGKRSSRKDIND-EDDED-AEQSSE---EDEIGNNDGSEESEDQESN-FENIEEEERNLLHKMKQNAQEDVTKGQHGLWDTFLDTRIRLQKAVSIANSFP-AIQETRTLVDSLIDLTEYLWKMKEL--YRTQTIDKWSNKVQIASKAINQG-VNTQIEQIL-HD-ERLTKRTQLKREIF-DDTDFYQQLLRELIESRKQ--VDTKASKGRRLRYHVH-EKLQNFMVP-IPEDMIDELYSSLLGKNRLRIF Hisca1 SLAE--QIADQDPTP-KDFDPEDSSGAEA-GREHYISVGKSKLRKPYAGSRVSREALSDGSEDDESADELD-SSDA--GVTD-DQEFGD--SND-DETMVSDHKTVAASLSQAAKADAAKGSASAFGAILNARIKLQKGITILNGLPASIKSAEALWSTIEDLSADIWNMEEI--ERRAVLDKWALKIRGSRAVDQQT-ITSVLDAHIATE-SHPSKRTMTDKEIY-DDSIFYQALLRDLVEERKR-SVDTKASKGRKMRYTVH-EKLQNFMPP---DRARGEFFASLLGRDGLRLF Klula1 SLAE--QIADNKPQV-EDFDIENS----ELKKQHYVAVGKSKLRN-YVGSKGSRAEL----DEEMDAPEQGESESE--SGSEEE---DVSESEATSESVQTQTKQVINNLAHSAQRDASKGYAKFFDKILDSRIKLQKALSASNQLPKLLTSTFKVLTQCVTVFKELVHTVTL--DRSAVLNKWSAKVSASSKAINQS-ADVQVDNQL-ADMPRLLKRTKLNRYIY-DDEDFYRVLLNDLVEKKKK-NIDTKASKGRKLNYSIQ-EPIANYEAS---DEQIDEFFAGLLGQD-IQIF Lacbi2 SLAQ--QITQEEAAP-VDFDPEDEDQMDA-AREHYVEVGPSALR-NYDGVRTSRKQLED-SDLEGSNGGED-FDEEDERDDEVEDSEES---VE-EEESPEAAEDMTSAMKVKREEDRKKGKAALWDTLLDTRIRLQKAVVASNDLPGALRKVLELADDLFDLVSESSENSAL--ELNQTLSKWSSKIQAVASQNIKS-AVQLIDETL-AD-EKLVEKTQVRREIF-DDTDFYQKLLRDIIDSRKK-KVDTKASKGRKLRYEVH-EKLQNFMVP-VPEEQIDELFGSLLGKSGFRVF Lenti61 SLKD--QLAQDQPAP-IDLDPEDEHRFDA-AREHYVDVAPSALR-KYDGIRTSRRHLED-DEPVSEDGDEIGRDREDGSQEDEETPHSRTQVSE-ASA-----GDIAAHLRITHEADRRKGKAALWDTLLDARIQLQKAVTAANRLPEAIDSLLDLTDELFSLLQELSNASVL--ELVETLSKWSAKVQAVAKSAQVG-VVGLIDELLRSD-TKLLDRTRKQKEVF-DDTDYYQQLLRDVITARKK-TVDTKASKGRKLRYEVH-AKLQNFMVP-VPEEQIDGLFSSLLQS------ Malgl1 NLDA--LLKVQVCLP-LAIDPENNESSDA-ARQHYVDVGPSQMRRKYKGVKASRAEMSD-DDDDDDENYDDDDNGDQEEDEDEDENEDENEDEDRDEGQEKESQTVLDQIREKRAHDARKGQHRNWEKALRLRISFQKLVTGASRLPDDIDKAAAIAAQLLDIVEASQSLEDL--EIHHLLTRWSNKIASAPRAMNQG-IVDQIEQALAGD-DRLVNRTRVWRNVF-DDSDFYSQLLRDLIDNAKR-NVDVRASKGRRLRYDVM-EKVQNFMPP-IPEAQTERLFASVTGADGFRLL Mellp23 SFSD--LIKSSSSTP-AELDPEDKPT----SQTQYHSVPPSKLRNQYSGKKVSRKDI--------------------------EDEP------------------LVKQLQASVKADLVKGKAAVYDSLLGFRIGLQKVLTATNEI-YSTQTVLNLSSSVGNLLESCIETQEL--DLRTTIQKWSTKINSAT--VNQN-VLNQLDTLWKMS-ERLIERTRLKRDQF-DDRDFYLSLLKEVVDTNHHPNVDPKASKGRKIRYHVH-EKIVSFMVP-VPDESKDELFGSLLGR-VFELY Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr SFLQ--ELAENNTRP-ADVDPENWQGVKR-RQPHLG----------YRGRAVSRRDI-E-QEDEDDEEDE----DDNEEDEDVEMDDDEDDDEDGDDDLAQEEAAVAQSLTSDTAAQRKKGEHALWDAALEARIRIQPALAAANRLPEELAGCTELAEAIAQLDEELSAISAV--ERDQLLDKWSRKTRLATKALDRG-LLQQISDVA-ED-PRLIARTRVKRDIF-DDVDFYHEQLRELIERRKR-LVDTKASKGRKVRYDVQ-PKLVNLMAP--NDAARDTLFASLFGK------ Morel2 SLAE--QLAESTTTP-KDYDPEDSDMGSA-GREHYVNVGKSQLRSKYKGKKSSRKAASD-EDEEEDDEEEMEEDQDEEENDDDDDEEEEDDEEN-SQDIQREESELLKSMTKSVTDDVEKGIHTLWETLLDTRIRLQKSVSLINTFP-PMEEAKHFIDTLITVQTKAWKIEGL--DRNNTLEKWSNKVQIASKAMNQG-IMTQISQTM-AD-ERLLKRTQLKREIF-DDGDFYQQLLRELIESRKQ--VDTKGSKGRRLRYHVH-EKLQSFMAP-IPEEMIEELFSSLLGRDGLRIF Mucci2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma TILD--TLKDSSSLP-FN-DPEDDPNFDL-LSSKIGSLRNK-VSNIYFGKKISRKVI-N-DDSIEAENGSSE--DENENGSSNDDFDEEDYNND-DNDIENFN-------TTKVEEDVRKGTAELLDKLLESRIRLQKSLHIVNRLPDHYHTAKNLLDQLLKLVKDYEEISKR--HHESVINKWYERTRLGSSAFDKS-TLQQINQVL-TD-ERLVKRTQLKRQIF-DDNDFYHEMLKELIERKKR-KIDTRASKGRKVRYDVH-PKLVNFMAP-QKDQARNDLFSSLFGQ------ Neucr2 LRAS--MF--DEKPA-KDYDPEAQSGSEA-ETEHYVTVGKSKLRKAYSGTRVSRKALES--DEEEDAEISSDSEDDEEEGEDDDDEDDEEDEDE-DEDMAEDEKKIVSTFSKAAEADAQKGVARIFDSILNLRIRLQKALIAANTFNKPYEAAEELWNTIDSVAQEIWELEAV--ERRQVLDKWSTRVRSTTSAGSQS-LVSVLDDQLLSA--RLIKKARTPRDIY-DDADFYQLLLKELVDQRRK-QVDRKASKGRKLRFTVH-EKLQNFMAP---EHAIDRFFGTLFGQAGLKLF Orpsp11 SLGD--ILKTNNPAP-AEVDPEESLLTGA-EREHYINVGPSKLKNSYQGKKSSRKELSS-EDEEDDEEINSE---DNEEDEDEEEEEENEEESD-NEDLEKEQNEMVNNMSQSIKSDIEKGKQSLCDSLLDLRIRIQKAVNIANQLP-KVNETKKLINDLLQILDDLWEINDY--NQNDILEKWNRKVQTTAKAVNQS-IVSQIEQLL-SD-DRLIKRTQLKREIF-DDTDFYQQLLKELIESRKK--VDTKASKGRKIRYHVH-EKIQNFMVP-IEEEMTNELFKSLFGRDGLRIF Pench1 SLAD--QLADEDPTP-KDFDPEDSE--NT-GREHYETVGKAKLRKDYDGARVSRAALAE-SDEDEDSDISS-SDDA--GGED-DEESEE----D-DEDMATDQKTIAATISSAAKADATKGKATTFDALLNARMKLQGGLTSINGIAEAIKSAESLWSTLEGLSASLWEMAEL--ERRSILDKWSSKVRGTSSGRQQT-ITAVLDAQVATE-ERSSKRSRTSD-LY-DDGAFYQSLLRDLVEQRKR-DVDTRASKGRKMKYNVH-EKLQNFMAP---TRARDEFFASLLGKGGLRLF Phybl2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 TLAE--QIAE-APKT--DFDIEDSGASDSLRNEHYVAVSKSKLREKYNGSVASRSDLGD-GDENDEEDEEDEDDDD--DDDEDEDE-DDDELEENEDEMSQERSHIVNRLSQSATNDSLKGFASTFDKIIDARLKIQKSITNANLLPKYLLKAKELLESIMSLLEEFSNTEKF--DRSGALTKWSAKVQNASKSINQS-FEQQVSNNL-ADMERLVKRTKLNREIF-DDEDFYRVLLNDLVDKKKK-NIDTKASKGRKLKFQVQ-EQIANFETP---DNQIDEFFASLLGQ------ Plicr1 SLAQ--QLAQEDTAP-VDFDPEDEDEGNA-ARDHYVEVGPSAIR-KYDGVSTTRSQLAQ-N------ASDG-SDTD--DGDDID------------SEPA---EDLSSTLRKTRDEDRKKGKAAIWDALLDARIRLQKSSTAANKLTASLDTLLSLSDELFDLLFDATRAAAL--ELVPTLQKWSAKIQAVAAHAPKS-AVQLVDDAL-GD-AKLLKRTRTRREVF-DDTDFYQQLLRDVIDARKK-KVDTKASKGRKLRYEVH-EKLQNFMVP-VPEEQIDELFASLLGKGGFRVF Polpo -LSD--EITQSDNAP-KSFDPESEDFGD------------VRIRGEYAGKKSSRKE----NDLEEDE------DEEEDDNQDDEDR------------EDTEQPKLVS-KNSAISAELEKAKNDLFDEFLTTRIHLQKTIGIANRLPLKFEEAVGLLGDLFSLLGDIWTIEEQ--NAGESIEKWNNRVNLTVKSINQS-IMTQVNNTL-NDIERLHKRTRLKREIF-DDTDFYQVLLKEIEKTSKKRPTNNKASKGRQLRYETF-TKLENFMPP-VP--NLDDLFSNLFGG------ Pucgr2 TLAS--LFKKSQPNP-EEIDPEDKRTGE--ENEKRIGMGASQLRQ-YAGRLVNVHDW-------------DNSDNNSQDDVDEDDEDDENLENDQEEDTHDQPSDLIKHLQSSVKADIEKGKANTYDRLLAIRIGIQKPLIATNKL-EEVRMALNISAQIGTLLKESLEADRL--DLRTTVRKWSTKINSTTTKQEEN-VMDQIEQLWASK-EKLVIRSRTSKQIF-EDRDFYLSLLKDVVQTAHREAVDPKASKGRKIRYDVH-EKLVSLMVP-IQDPQKDELFGSLFGFDGFKLL Punst1 TLAQ--QVAQAEATP-LDFDPEDEDDGPA-ARAHYVDVGPSALR-RYAGARTSRARLDT-ADSPSEDEDEDERYGDDSSDDEIEDQDDDDEALS-PTH-----DALSTALRQKREEDVKKGAAAIFDALLDARIRLQKTVSASNSLPSAIQRTLDLSDELASLVHDASLLFAF--ELLRTLAKWSSKISAATAAAAFS-ASAQIDAALAAP------RARSQRDTFDDDTAFYQQLLRDVIASRKS-VVDTKASKGRKLRFEVH-EKLQNFMVP-VPEAQVDELFASVLGKGGFRLF Rhior3 SLAD--LIADESTAP-VDYDPEDQDEGNT---AHYVSVGKSKLRSEYAGKQTSRKDI-S-EDEEEDEWQGIQTDSEEEDGEEKSDEEVSGEGSE-YEDIQEEEKQIISQLSKSAQSDVEKGQHTLWDNCLENRIRMQKVIDNANKLPEDLEQVKTVIDDLMDIIEKLWKMSEI--NRNSTLEKWSNKVQVAAKAFDQN-IMAQIENVL-HD-ENLVKRTQLQREIF-DDQDFYQQQLRELIESRKA--VNTKASKGRQLRTEIR--------------------------------- Rhoto1 TLAE--QLAQSQPAP-QDYDPEE-NRTSA-ARAEFVDVGVSKLR-KYEGKKGSRAALAD-TDDEDEGEEEDHEDEDEDEDLEAESIDSDG--------KQQDERSMVSQLKQAATADVEKGRDAFCDSLLESRIKLQKAVGAANLLPEEVGDVLDLSEELFQLLDLTLALKTL--ELRSTVTKWSDKVLAASKAVNQN-AMAQIDHAMSGA-ERLIRRTRIRRECF-DDSDFYQQLLRDVVESRKK-VVDTRASKGRKIRYHVH-EKIQNFMIP-I-DEQTDELFAGLLGRGNLRLF Rozal11 -----------------------DEFSD-----------------------------LE-ESDEEIEFEDIQ--------------------------IEDEEEYQIQMISKSNINDADKSTHGLWEDSLGVRIQMQKLLLNANQWP-------------------IWQIQKV--DTKESLDKWHSKVQMSSKNINQP-ILDQVKHVM-TD-ERLIKRTRLLRDIF-DDTDFYQQLLREYINNKQN--VDRKASKGRKIRYEVH-PKLQNFMAPVIDDDKISDLFVSLFGK------ Sacce1 SLAD--QISDIKPVN-KDFDIEDS----ETKKAHYLEVEKSKLR--YTGVKGSRQAL-----EEVSENEDEEEEEE--EEKEEE---D--EEVEIDEEIQQETKQAINKLSQSVQRDASKGYSKLFDNIIDLRIKLQKAVIAANKLPRLLKENEKLFNRLINFLKELYQTNSL--DRTAVLNKWSTKVSSASKAINLP-ADVQVENQL-SDMSRLMKRTKLNRYVF-DDEDFYRVLLNDLIDKKKK-NIDTKASKGRKLNYSVQ-DPIANYEAP---DDQIDEFFAGLLGQD-IQIF Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 SLAQ--QLAQDDTAP-VDFDPEEEDAEMA-GRGHYLDVGPSNLR-KYEGKRASRAQLGD-DDEEEDEEDEG-EDADRPDGSEEDGMEDEEDASE-EEEPAPKTDDLTDSLRKNREADVRKGKAAIWDTLLDARIRLQKSVTAAQKLVAALTGMLDLSDELMSFLRGLTEVVAL--ELVRTLTKWSAKIQAVASAQPKS-AVALIDETL-AD-NKLLARTRVRREIF-DDTDFYQQLLRQVIDARRK-KVDTKASKGRKIRYDVH-EKLQNFMVP-IPEEQVDELFASLLGR--FRVF Schpo1 SLKD--ELAGLNPQP-QERDPEAEDSSETLGREHYVDVSESKLRSKFKGRKTSRQELEE-EDSEEDENDAVS-----------ENFSSSEASSISEENIINGEKKLSDQIRTSALEDMKKGLARFYDNVLDTRIRLQKLLSSSNQL-GDKVEARDFIQHTLQLLEEIALMNNL--DKNDTLTKWHNRVQAVQKALNQS-IVQQIENSM-IN-KDLVERTRIDYEIY-NDTDFYQSLLKDFINSREN--VDTKASKGRKIRYHVH-DKLQNFMAP-IEDEQTEDLFSSLLGQDGFSLF Sorma LKAS--MF--DEKPA-KDYDPEAESGSEA-ETEHYVTVGKSKLRKAYSGTRVSRKALES-DDEEDDAEISSDSEEDEEEGEDDEDEDNEE--DE-DEEMAEDEKKIVSTFSKAAEADAQKGVARIFDSILNLRIRLQKALIAANTFNKPYKAAEELWNTIDSVESEIWDLEAV--ERRQVLDKWSTRVRSTTSAGSQS-LVSVLDDQLLSA--RLIKKARTPREIY-DDADFYQLLLKELVDQRRK-QVDRKASKGRKLRFTVH-EKLQNFMAP---EHAIDRFFGTLFGQAGLKLF Sphar TLAE--RMAS------LTAEPETSEDSD--QVDESMTKQRSSLRKSYAGKKTSRASL---TDQGVDSTSEEDSDSDGVDGSEAEEVSGDDEGSE-DEQDEQEAAKGISHFSKTVTEEVTKGVHTLCESVVETRIRLQQALNLNNQFPKSFEAAKKFIDSLLELSSSYHKTKSV--ERSHTLQGWHTKLLLSSKSVNRD-IPTQVDQMM-AD-DTLVKRTQLKREVF-DDNDFYHQILREFIASK---SGDTHGRQGMRKRMHIA-AR------------------------------ Spipu1 LLES--LLDESSTTP-VDFDPEKSEAEGATATEHYVAVGRGKIRNQYAGRKVSRKKA---EEEEEEEEDESESEGDEEPSEDEEEEDMQYDESD-SHDLEVEEKKLIKSMSVSAKADVEKGQHSLWDSLLDGRIRIQRAVAVANRFPDGIATASQLVDELLDLIQSIWQIEPL--DRDKTIDKWNNKVQLASKAINQS-TLSQIKQIL-GD-DRLIKRTQLRREIF-DDGDYYQQLLKELIETRKK--VDTKASKGRKIRYHVH-EKLQNFMAP-EPEEMVDELFAALLGQDGLKIL Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 SLAQ--QIAQDEPAP-LDVDPEAEAGEGA-AREHYLDVGPSILR-KYDGVRVSRKKLEM-EESQSGSADEGELENDDLSHDEDEEEEDE-DKDE-EEENA---DDLSSTLAQKREEDKRKGRAALWDSLLDARIRLQKFAVAANKLPEAQERLARLGEEICGFLKEASEVVRM--ELTQTLHKWSAKVAAVASGGVKG-VGEQVDEILRAD-EKVRKRTRVRREVF-DDTDFYQQLLRDVIEAKRK-NVDTKASKGRKLRYEVH-EKIQNFMVP-VPESQIDELFASLLGKKGFRVF Tapde11 SLAD--QLASDNPNP-VDIDPEN-DEGD--GRSHYTTVEKSRLRDTYKGQKSSRKAISD-GSEDESDNSASDESGSEGEPGEEGSGSDQSNLSE-DEE--SDQKAIVQDVVKTATADAEKGKAGLYDSLLDSRIKLQKGLQSTNL--AMVADTEAFIESLLTL---LWKIRAQ--DRDQTLTKWSNKIQAASKALSQG-ILAQIEESK-SD-VKLLKRTQIKREIY-DDGDFYQEMLKDLIDSRGQ--VDTRASKGRKLRYHVH-EKIQNFMAP-MPEEQVDELFGSLFGQDDFKLF Thetr SLAD--QLAEADPTP-RDYDPEDDRASDTVAVGYSVEEGVNDARHRYAGEVVSSRKV---DRGE--------SGSDSGSGSSQSESSGSGSESGAESELQSSNASNVAYLKSQREDEMVRARARIHSAVLQSRVTLQQPLELGNRLPKAAAEARATLAVLGELLDELWELAAR--QCEAVIDAWNRKAMLAGKTLHRP-LVEQIHDQL-RD-SALRATSQKLRHVY-DDADFYQRLLQQLITTGKK-LVDTRATKGRKLRFNVQ-PKLTNFMAPKVLDEAAGGMANGLFGY------ Treme1 TLSQ--QLKLTLGQE----DQVDGLVND--RREHYVDVGPSKLRAEYAGKKASRVRI---DDDDDEEEKGDDGEEEEEEGFDEEDSEGEDDEEN-EED-----LDPIASLRESRLKDIEKGRGALFDQLITLRITLQKAFSSAYKLPFKRDEALELSEDLFTIDEEYWFRQSL---VVPILSKWATKIHAAS-SSTAD-VFEVIDAGLAAK---------------------YRALLREVIDSRKR-EADRGGSKGRKLRYTVH-EKAQNFVVP-IPEEQIEELFSSLFGGGGLRVF Trire2 GRAK--DFKDDEELA-KDYDPEADNGSGA-GTEHYVTVGRSKLREKYRGSRVSRQALQE-SDDESDSEISSDSEDEEGDGLDDDEDDDEE--EE-DEE-KQSAKPSLATPS--AQTEVQKGIAKIYDGLLNMRIRLQKALVAANTFPEAYEAAEELLNTISDLNEQIWELQED--HREDRLDKWSRKVQSVTGAKPKT-LIEALQDQLANP-DRLVKRTRVPRDIY-DDADFYQLLLKELVDQRRK-VVDRKASKGRKMRFTVH-EKLQNFMAP---QEAIDRFFGTLFGQEGLRLF Umbra1 SLAE--QLADDTTAP-ADFDPEQGDFSETNARGHYVAVGKSALRKSYGGKRSNRNAINE-EDDQEISEDEVD---DEESSDDD-GEESE--EGD-FEQLREEEKKMLSNMSKSAKSDVEKGQHNLWDGFLDTRIRMQKAMNITNQLPPHIEASKSLIDSVMDLVDKLWEMSQL--NRNATVEKWGSKVQIASKAFDQS-IMTQVNSIL-GD-DRLVKRTQLRREIF-DDNDFYQQLLKELIESRKT--VDTRASKGRRLRYHVH-EKIQNFMVP-IPDGMTDELYASLLGRDGLRIF Ustma22 SLAS--LLGTTNAAP-VDFDPEADEDEDMNPRAHYADVATSDMRKRYHGVKSSRAELHA-SDDDQDD-----DDQEDEQDDED-------DESD-DDS--STSNSIAAQIAQSASQDAEKGRQKTYERTLETRIKAQSVLRDINRLPEQLLELSDLRTRLNTLVEQTWTVVGY--SRRRVLDKWSLKVTSAARAVNQA-PSSQIDSAL-AGLSRLVARTRVLR-VF-DDTDFYSTLLKELIERRKH-NVDTKASKGRKLRYEVN-DKLVNFMPP-IRPEQIERLFSSSMGVAGLRVF Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 LLAD--QISDNKPAV-EDYDVEDA----QLEKAHYAPVEKSKLR--YQGAKGSRESAQD-EDEDEDEDEGGSDEDE--SDEDEEDGEDQ-ESQEEDSPVQAERRKAVNNLSESTKRDASKGLAKLFDNIIEVRMKLHKAVTDVNRLPKLLKHTAKVMGEIVDFFEDLTKTEEL--DRSTVLHKWSSKISAASKAINQP-ANVQVENQL-ADLPRLVKRTRLSRYIF-DDEDFYRILLNDLVDKKKK-DVDTKASKGRKLNYAVQ-DPIAHYEAP---DEQIDEFFAGLLGQD-IQIF [Cluster2426.fasta_al_trimmed; alignment length = 112] Allma1 RRTVKVTKGGKVVSMSAMVVVGD-GNGTVGYGEGKDADAIKNMIAIDRYDEDLAHEATRVE-MRAAPPGFGLRTNPNVHEICRCAGIQDLSAKVMGS-RNPINVVKATFQAL Ashgo11 KRVSNQTAKGKIASFYSLVVVGD-RNGMVGLGEGKSREAIKNLKHIPRYENDIDFRGVKLH-LRSAKPGFGLRVNHVIYEICECAGIKDLSGKVYKS-RNEMNIAKGTLEAL Aspfu1 HAVVNQTRLGKVRRQYCLSIAGN-GNGLLGIGEAKSEEAIRNMQPILRYEDDVEGKAVELK-LMTRPPGFGLRCQHLIFEMCRACGIHDLAARVTRS-RNPMNTVKAAYEAL Aurde31 RRTTQQTGKGKINSMYVCVVVGN-GDGLVGVGEGKDMDAVRNMDVVERFEGEVQSKATRII-MRPRPVGFGLHCNPYIHQILKAAGIKDISAKVWGS-RNPLNVIKTAQRLL Batde5 RRVAHVNSGGKQRSISVLAVVGN-QNGSAGYGMGRALDAEKNMIHFNRLDNDLEHTKTVLQ-LRTASPGYGLMVNRNIHEVCRCIGITDLSGKVRGS-LNPMNVIKATFDAL Botbo1 KRVVQQTGKGKIPSMYALVVVGN-GRGLVGYGQGKGDGALKRMDTVDLFENNIDIKATRIV-MRPRPVGFGLAVNPYLHQVCKAAGIKDLSAKVYGS-RNGMQIIKAAMMVF Botci1 HRVVNQTRLGKIDSMYVLAIAGN-GRGRLGIGEAKGQEAIKNMQPVPRYEEDVEGKAVEVK-LMARPPGFGLRCQKLIFDMAKAVGIHDLSAKVPRS-RNKMNTVKATYQAL Caeel ---------------------------------------------------------------------------------------------------------------- Canalb1 KRVSLKTAKGNIANFFVLSVAGD-KNGMVGLGIGKSRDAVKNLTPVYRYEDSFEYKATKLK-FSPAPVGFGLRCNKNIFEICQAAGIKDLKGKIYKS-RNPLTVANGFFKAL Cangl KRVSNQTGKGKIGSFYALVIVGD-RNGMIGLGEGKSRDAIRNLKEIPRYENDIDYRGVKLH-LRSAKPGFGLRVNHVIFEICECAGIKDLSGKVYKS-RNDMNIAKGTIEAL Capow KRVSTMLRTGRRHMMQALALVGN-GRGVIGFGMSKDAVACHNLYPIPRFNMPMENKRSLVK-MWPAPQGHGLVCHGVIRMIAELAGISDLTATVINSKRNYHNIVRATVFSL Catan2 RRTVKVTKGGKVVSMSALVVVGD-GNGSVGYGEGKDAEAIKNMIAVDRYDEDLDCKSTHIV-MRAAPPGFGIRTNPNVHEVCRCAGISDLSAKVMGS-RNPINVVKATFLAL Cioin ---------------------------------------------------------------------------------------------------------------- CocheC53 HGVTNQTRMGKIRSLYYLTIAGN-QDGLLGVGEGKSVEAIRNMRPVPRYENDLEKKATKVQ-LFSRPPGFGLRVQHLIFELARAAGLQDLSAKTPRS-RNKMNVIKATWEAL Coere1 KRTVQMTRNGKIPTMYALVVVGN-GNGAAGFGEGRGPEAIKDIQMIPRYDDDIDHKATKLL-LWARRPGFGLRVAPIIHEICQCIGIKDLAGKIHKS-RNPMNVIKAVFEAL Conco1 RSTVNMTAKGKIRSRWALVVVGN-GNGAGGYGQAKAEDAIKNMVAFERYDNDIEHKATNLK-LFARPPGFGLRINMYIHEICQCLGFRDLSGKVYGS-ANPMNVVKAFFEAI Conpu1 RRVTQQTGKGKIHRMYTLIVVGD-GNGLVGFGEGKDEEAVRNMDYVERFEDDMEAKGTRIL-LRPRPVGFGLQCNPNVHQVLKAAGIKDVSAKVWGS-RTPLNVIKALFRML Copci RGVVQQTGKGKIRRVAYMVLLGN-ADGLVGLGEGKHANAVRKMDWVERFEKEMRTKSTELI-LRPRPVGFGLRCNPYLHQILRAAGFKDISAKVWGS-RNRLNVIKAAFRLL Croqu1 KRVVNQTGKGKIPSMYTLVVVGN-GKGLVGYGEGKSETAIRNLSPVNLFEGELRSKATEIV-MRPRPAGFGLRVNPYLHQVAKAAGISDLSAKVTRS-NNPMNVVKLCLMML CryneH991 TKVQHMTKKGKMASQQAYVVVGHPEKGLVGLGRGRGHSAVLNMDYVNRYEEDLQGKAAKVH-LRARPPGFGLMVPPMIHRVFTACGIKDASAMIVGS-RNRPDVLKATIQVL Crypa2 RYVSNQTRLGKIRSSYVLAIAGN-ENGRLGMGEAKSVEAIRNMQPIRRYEDNVAGKATVVN-LYARPPGFGLRVSHRFFEMARAAGISDLAAKMPRS-RNPMNSVKACFQAL Debha1 KRVSCQTSKGKIPNFYALTVVGD-KNGMIGLGEGKSRDAVKNLTPIPRYEKDIEYKAVKLF-IKSAPSGFGLRVNPNIFEVCQAAGIKDLRGKIYKS-RNPMNVTKGFVEAL Dekbr2 KTVRNQTSKGKINSFYALVCAGD-RNGMLGIGEGKDPEAVKNLVAVPRFERSCDSKATIVQ-LRSSPAGSGLRCNPMIFELAQCAGIKDLSANVYRS-RNKMNVVKCTMQAL Dicdi SRHVKVTTAGRVQSFSVTIFNGD-GNGTAGMGYGKGDSSERNAFSLDRYNHGLDFKSTKVKFIKSRPMDFMDHRGIKPSLILPTIGLHGVTFRTYGK-KDWNSVLKAQNKTL Dmel ---------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------- Fomme1 RRVTQQTGKGKKHRIYSLHVVGN-GDGLVGYGEGKHAEAVRNMDAVDRFERDMSIKSTRIL-MRPRPVGFGLHCNPNIHQVLKAAGIKDVSAKVWGS-RNPIQVVKATCMLI Fusgr1 RWVSNQTRLGKVRSTSVVAIAGN-GNGRLGLGMAKSTEAIRNMKPVRRYENNVTSKGTVVE-LMARPPGFGLRCPHRIFEMCRAAGIHDISARMPRS-KNPMNSVKAAYQAL Galma1 RAVVQQTGKGKIRRVAFMVLVGD-GNGLVGYGEGKHSNAVKNMDWVERFEKEMSSKATQLI-IRPRPVGFGLRCNPFLHQILRAAGLKDISAKVWGS-RNKLNVIKAAFRML Ganpr1 RRVVRQSRAGKVRRMWAMVVVGN-RNGAAGVGEGKATEAVENMAPVARYENDVEHTSTRVR-LWARAPGHGLVANPHVHTLLTACGVHDCASKVTGS-TNPMNVVKAAFEAL Gloin1 KRVINQTEKGRIPSMYVLVVVGN-GKGVAGFGEGKHDEAIKSLRYFERYDDDIEHKGTTIK-LWVRPPGFGIRCNHYIHEIAKCIGIQDLSAKVFGS-CNGMNVIKCTFEAL Hisca1 RMVSNQTRLGKIRQTSILSVAGN-GKGLLGIGEGKSRDAIRNMRPVLRYEDDVRGKATELQ-LMHRPPGFGLRCQQSIWEMCRAAGIRDLAARVTRS-RNKMNTVKATYEAL Klula1 KMVSNQTAKGKIPSFYSLVVVGD-KNGMVGIGEGKSREAVRNLKEVPRFEKDIDYRGVKLF-LRAAKPGFGLRVNHVIYEICECAGIKDLSAKVYKS-RNIMNIAKGTIDAI Lacbi2 RTVVQQTGKGKIRRMSFMVLVGN-GDGLVGYGEGKHLNAVRNMDWVERFEKEMKTKATQLI-LRPRPVGFGLRCNPFLHQILRAAGFKDISAKVWGS-RNKLNVIKAAFRMI Lenti61 RFVKQQTGKGKIERIAILMVVGN-GKGLVGLGEGKGSDAVRNMDYIERFEDAMESKATRII-LRPRPVGFGLAVNPIIHEVFKVAGIKDASAKVWGS-RNPYQVMKAVVRML Malgl1 KRVVNMTGKGRVPSWYSLVIAGN-GRGLVGYGEGKDTNAVKNMDLVSVHRSPVEGHATRVA-IRPRPAGFGLRVPNVLHPIARAAGFTDLSAAVYGS-SNAMNVIKAALQVL Mellp23 KRVVNQTGKGKIPSMYTLVVVGN-GNGLVGYGEGKSETAIRNLSPVNLFEGELRSKATEIV-MRPRPAGFGLRVNPFVHQVAKAAGISDLSAKVTRS-NNPMNVIKLTLMML Mnele ---------------------------------------------------------------------------------------------------------------- Monbr KRVINMTRGGRQSSMWALVIVGN-KKGVAGFAIAKAEDAIRKAVFIDRFDETIHHKRTKIF-LRPKRPGGGLIAHRSVMGIAELAGIRDLGADIIGS-NNPLNVVRATFGAL Morel2 KRTSNMTTAGKIPSMYALVVVGN-GQGIAGYGEGKDDEAMRNLTAFERYDDDIDHKATNIQ-FRSRPPGFGNRCNHYIHEICSCIGILDISAKVWGS-RNPMNVIKATFEAL Mucci2 KRVVNMNGKGKQPSMYALVVVGN-GNGLAGYGEGKDEEAIKNMRYFERYDDDLTHKATTLE-LRSRPPGFGIRTNHYVHEICRCIGLQDISAKVRGS-TTPMNVIKATFEAL Mydma ---------------------------------------------------------------------------------------------------------------- Neucr2 RRVVNQTRLGKIASDSVMVIAGN-GDGWLGLGMAKSVEAIQNMQPIPRYENEVTTKGTIVR-LNSRPPGFGLRVSHRIFEMCRAAGIRDLSAKFLRS-RNPMNTVKATYQAL Orpsp11 ---------------------------------------------------------------------------------------------------------------- Pench1 HSVTNQTRLGKVRRAYRLSIAGN-GNGLLGIGEAKSDEAIRNMQPIPRYENDVKGKATELQ-LMHRPPGFGLRVQYLIYEMCRAAGIHDLSARVGRS-RNQMNTVKAAYEAL Phybl2 KRVVNMNGKGKQPSMYALVVVGN-GEGLAGYGEGKDEEAIKNLRYFDRYDNDIVHKATTLE-LRSRPPGFGCRANHYIHEICRCIGIQDLSGKVRGS-TTPMNVIKATFEAL Picst3 KRVSLKTSKGNIPNFFVLTVVGD-RNGTIGLGIGKSRDAVKNLTPIPRYEEDFEYKAVKLF-MRSAPAGFGLRVNRNIFEICQAAGIKDLRGKVYKS-RNPLLVCQGFVEAL Plicr1 RRVTQQTGKGKIQRMYYLVVVGN-GDGLVGYGEGKDEEAVRNMDYVDRFEKHMESKGTRII-LRPRPVGFGLACNPNIHQVLKAAGIKDVSAKVWGS-RNPINVIKTLCRMI Polpo GRHVKVTKGGRINSFSTLVFIGN-GAGTGGLGYGKGETAERNAITINRYLDGLDLKSTKIRFFKTGMTD-MSLSGEKQDIILESLGLHGVDFRTYGR-RSWRNIFNEKRETL Pucgr2 KRVVNQTGKGKIPSMYTMVVVGN-GNGLVGCGEGKSERAIKNLAPVNVFEGELKAKATEIV-MRPRPPGFGLRCSPFIHQVAKAAGISDLSAKVTRS-NNPMNVIKMALMML Punst1 RRVVQQTEKGRRPRFSVLAVVGN-GNGLVGYGEGKHEEAYRNMDYVPRFEKPLRTKSTEII-LRPRPVGFGLAVNPNIHKILTAAGIKDCGGKVWGS-RTPLNVIKGTFRML Rhior3 KRVVNMNGKGKQPSMYALVVVGN-GNGLAGYGEGKDEEAIKNLRYFERYDDDLTHKATTLE-LRARPPGFGIRTNHYVHEICKCVGIQDISAKVRGS-TTPMNVIKATFEAL Rhoto1 KRVVNMKAKGKQPSIYALVVTGN-GHGLVGCGEGKDDAAVRSMDYVERYEENMNSNTCKIE-MRSRPPGFGLRVNPHIHQVAKAAGITDLSAKVYGS-RNPVRVIKLACAML Rozal11 KIIKRRSKTSKKGFFWTFSAAGN-GKGAVGVGIGRDEAARKNM----------------------APPKHGVRAHHAIQNICKVAGIRDLGVRTYGS-KHPMNVAYGFMEAL Sacce1 KRVSNQTGKGKIASFYALVVVGD-KNGMVGLGEGKSREAVRNLKEIPRYENDIDFRGVKLH-LRSAKPGFGLRVNHVIFEICECAGIKDLSGKVYKS-RNDMNIAKGTIEAF Salro PAVPPLPAREKI------------TPGVIH--------TVLGMQP------DVQAKKTKVY-MRPAKPGHGVKAHPLIQMMCELAGIEDLTADVVGS-TNPLNVAHAAMEAF Schco3 RFVSHQTGKGKIARYNMMTVIGN-GDGIVGFGQGTHEEAIKNLDYVDRFEKDLETKATRVK-MRPRPLGFGLMCNPNVHQVLKAAGIKDISAKVWGS-RNKIQVIKATLRMI Schpo1 RRVVNQTRKGKIASMYVLTVVGN-RNGVAGFGEGKAESAVKNMVYIPRYDKVIHKKAVRLT-LRSRPAGFGLRCNPILHEICRCAGIKDISGEILGS-KNGMNTVKAMFEAL Sorma RRVVNQTRLGKIASASVMVIAGN-GDGWLGLGMAKSVEAIQSMQPIPRYENEVTAKGTVVR-LNSRPPGFGLRVSHRIFEMCRAAGIRDLSAKFLRS-RNPMNTVKATYQAL Sphar ---------------------------ALGYSTGKSYTAIRKLVHVRRYNDPIYVKKTRLY-LRPSRVGHGTVAHEIVQDLCELAGVHDISSNIVGS-TIPLNIVKAFFIAI Spipu1 RRVARVNSGGKVRSVSALVVVGN-GNGAAGYGEGRATDAEKNMTYFHRFNNNIDYNKVQLQ-LRSAPPGYGVVASNHIHEICRCIGISDLGAKIWGS-RNPMNVIKATFAAL Sporo1 KRVVTMKSKGKMPSMYSLVVVGN-GKGLVGVGEGKDDTAVRSMDYVERYEDTMKSNTCKIE-MRSRPPGFGLRVNPYIHQVAKAAGISDLSAKVYGS-RNGTRVIKLAVSML Stehi1 RRVVQQTGLGKMPRIAILVVVGN-ANGLVGMGEGKHINAIRNMDYVERFEDEMESKSTKII-LRPRPIGFGLHCNPYIHQIAKAAGIKDISAKVWGS-RNPINVIKLMFRML Tapde11 RRVVNQTRKGKQASMYTLAVVGN-GAGMIGYGEGKHAEAVKNMEYVPRYQNEFDYKAVQLK-LRSRPAGFGLRANHFIYEICRCAGITDISAKVWGS-RTGMNVVKATFEAL Thetr NRVVNVTKGGRRQSFNALVVLGN-MRGSAGFGFGKGTDAHKNVIYVDMYNGELFYKASKVL-IRPQRKDGPYRAGRPYLPVLEAFGFKEVSIKTHGS-RNMLNVLKAIWNAL Treme1 KAVKHMNKKGRQPGQYALAIVGCPKRGLVGFGQGRGERATLRMDRVSRYENELTSKATIVK-FRARPAGFGLMVPRTIHPILTACGISDASATIEGS-RNPMHVVKATIQLL Trire2 RWVTNQTRLGKVRSTSIVAIAGN-GNGRLGLGIAKSTEAIRNMKPIRRYENNAKAKGTVVE-LFARPPGFGLRCPHRIFEMCRASGIHDIAARMPRS-KNPMNSVKAAYEAL Umbra1 KRVVNMNGKGKQPSMYALVVVGN-GNGLAGYGEGKDEEAIKNMRYFERYDEDVSHKATTIH-LRSRPPGFGNRSNHYIHEICRCVGIHDLSGKVMGS-RTPMNVIKATFEAL Ustma22 KRVVHMTTKGKDASMYALVIAGN-GKGLVGYGEGKDTNAVKNLDSVAIHKGQLEAKASRVV-LRPRPAGFGLRVPPVIHAICRSVGITDLSASIYGS-TNPVNVVKAALQIL Walse1 KRVMQQTSKGKIMSKYALVVCGN-GKGMVGVGEGKGDSAVREMDFVDRFQDELKSKSSLVE-LRSRPAGFGLRCSPVVHQVAKAAGITDLSAKCRRS-RNPMQVVKATLKAL Zygro1 KRVSNQTAKGKIPSFYALVVVGD-RNGMVGLGEGKSREAIRNLVSIPRYENDIDYRGVKLH-LRSAKPGFGLRVNHVIFEICECAGIKDLSGKIYKS-RNEMNIAKGCLEAF [Cluster2431.fasta_al_trimmed; alignment length = 184] Allma1 QELRNQRWAVLEQSAMALLDLGMI-EEAQKDIDVLDRKFA-GST-RVQKLTAMVHEAKGEFDHAMAYNQLLEQ--RPADTLMKRKIAVLKSQRQDAIAALNLLLDTLPSDAEAWLELADLYAGLQPAAHAVEEALLLLPTNATYADLLYARDLALKAYCRAVELVPAGLYGVVKCAREVAEKAL Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 SSLHLSQYREIEQLLLACLQTGDD-RSALSCLNQLEQRFGASNE-RVLGLRGIYEEAVAEDQSSLEYDTLLLE--NPANMVLKRRVALLRALSTDAIHSLIDLLKAAPTDAEAWCELSDLYKSGLQAIFCLEEALLIAPNAARLGELQHLLRGSIRSFSRSIELCDRGFYGLASVSERYAKTRI Aurde31 QRLATYRWGFLEQLALAALDIGQL-ELAYDCIAQLEERFP-DSP-RTNCLQGLVLEAQGQLDDALDYHKALEI--DEGNPYWKRKIAVRRQMGDKVVDELSAFLDTFYADADAWLELADVYASYTNALQCLSHAMLIAPQNLQAAETAYTVPLATRYYLRVVEM-DRAWFGVKLCTRRLATERI Batde5 QVMAT-RFAIIDQVFHACIDTGHI-EEAKDHLTTIEAAFPFGKSLRTRRLYGLYHEAMSDSTKAMEYNLALDT--DEASMLWRQSVARLISSNPQAIEALSLYVDRFMQDVEGWTMLAKLYADFEQAAFCLEEVLTLRPQHVRYAGIVSSLSLAVKVYSAALVTLPGALYGLRTVTKNIAKERL Botbo1 RALADYRPVFLEQLALAALDLGNL-DVADKCITDLVSQFP-GSP-RVECLQGMRIEATGRLKEALLYKDILKD--DESNAIWKRQISVLRQLSEDAVKELNTYLDTFYADAEGWLELADIYASYPQSLAALSHALLISPQNLQYAETAYTVPLALKMFLRVAEMVGRAWYGVKLCIRR-ATERL Botci1 -----------------------------------------------MAMRGLLCEVNAEDNAALQYEQNLSD--NPNNMILKRRISVLRSLGSEAIAALNELLDLSPTDAESWAELADLYASYPQAIFTLEEVLLITPNA---------------------------------ASSQLATSKL Caeel QALKKWRWAVLEQVCIAALDAARV-DLAQDCIDQLHAQFP-KSN-RVLKLKAMQLESTEHYQKALDYERLVED--EPNNNFRKRKVAVLLAQGLDAIRAINDYLKIFLNDPEAWLQLSELFLLVAKAVHCLEECVLISPLNRRLADLRYTVELARSYYERALKINPRSQYGILLSNNLIAIDNL Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ARLSELRWDVLEQVARAAMDCGEEESLAATLVKQLAARFP-ESN-RVKLLQGELFEAQGDWAGATQYDELLTE--TPNHAATKRKAVIFKSRGPKAISVLAAYVQQAMADYEAWVELSELYLSFQRAAFCFEELILSNPLSIRYAETLYTLQLARKHYANACKIQPRSLLGLYMTCSALAVSRL Catan2 NELRSIRWTIYEQLSIALLDIGDI-SHAKMCVGKLEKEFS-SSSIRVRKLHAMIAEASGDYDRAMAYNQIIEE--RESDMVYKRKIGVLKTQGKEAIAALNSLLDTIPSDPEGWLELANLYLSLQQAAFAVEEAILLLPTSLTYAQVQYAYELSLKSFCRSVELVPAGLYGIVQATSALAAAAK Cioin DTLREWRWLVCEQVYIAALDIGNY-DLANVCIEKLSDRFP-KSF-RVQKLRAMELEAKGQFDEAMEYKELEKE--DPTNAIRKRKIVILKAKGGDAIKSLVLYLQTFMADHDAWLELAELYIKYDKAAFCMEELLLSNPFNQRYAEIKYT---ARQYFAQAVKLSSRALYGLFLA----TAKII CocheC53 TALALSQWTIHENLFLSTLRTGDE-KAALDILHRLEARFGDHNE-RIITLRGIYNEATSKTDADLQYEKILKD--DPTNMIRKRRVAVLKALGQDAITAVAALLHNSPTDAEAWAEASELYASWGQAIFCAEEVLLITPNAAHIATLHYLLA--LKHFCRSVELNDRGYYGLKLLTSKLATNKL Coere1 ELLSEIRWLVYEQVFTAAIDEGQI-ELAKTILTILQKRFN-DSQ-RVRRLYGMINEAVGHPSEAKQYTQMLDA--DETNVASKRLIALLKAEGKEAISQLVTYLDTHANDFEAWLELCSLYLRYPQAAFCIEEVILQQPANLCYAEICYTLGTALKEYLRVVELSTRGFYGVKLVADRIATERL Conco1 DQLLYYIWEALEFIYLSSLDIGDR-ELSKNCLDKLSAKFP-DSL-RVKRLKGIWLESEQKFSEANTYAENLVE--LETHMSLKRQIAIYKSQGPDAIKALTLYLDVNHQDISGWLELSNLYLSYSQAAFCVEELILLDPNHLKYAEILYTFNLSLKEYCRVLELQPRAFYGIKLCCKRLATDQL Conpu1 EQLATYRWSFLEQLALASIDMGRY-DIADQCLKVLEERFT-GSP-RVDCLHGILMEATESPEIALKYNDLLEA--DSANAIWKRQIAVLRHMGEKAVNELSQFLDTFYADVEGWLELADIYATYENSLQALSHVIVLAPQNLQAAETAYTVPLSIRMFLMVVDMSDRAWYGVKLCSRRLATERL Copci QRLASYRWAFLEQLALAAIDLDRL-EVADACIAQLANKFP-DSP-RVDVLTGIRIEATEPLDIVLSYRELLQK--DSTNAAWKRKISVLRQKGDQATEELIQYLDTFYTDPEAWLELADIYVTYTSGLQALSHALALNPQNVQFAETAYSLPLALKMFLVAVDMIERAWWGVKLCSRHLATERV Croqu1 ARLKELRWAFYEQVAIAALDIGKH-DLARKAIERLEQKFP-SSP-RVMPLHGMLLEAKGELKLAKEYEAELCKSVDPKASMRKRLIALH--LHQEAVSLLVDYLDTVYSDPEGWIQLAEIYCKYDQALYALEDLILIQPDNLRYAETAYTYELAYKTYLRVIELSERAAIGLKLCLTKVLNEEL CryneH991 ELLAEWRWAVREQLAIAALDLGQT-LLASEQIEALYEKFP-GSP-RVRILDGLRFEADGDVSRARAYEALLKE--DETNIAHQRIISLALPSL-SAIPLLLSYLDVFYSDPAAWSLLADLYSEYSQSLGALGHLSIINSWDRRCGEVAYTYHLALKHFLRASEMQGRTWWGIKLAIQRLATERL Crypa2 QALELSQWITYENLLLSCLRTGDE-MSAHECLERLVKRFGDDNE-RIMAFTGLVKEAEASNNAELEYDAILAE--NNTNIVTKRRITLLRSLGAEAVSGLNALLDFCPVDAESWAELADIYFSYTQAVYSLEEVLVLAPNAARLGEVEYMLAESLKRFCRSIELCDRGYYGLKLVTTKLATEKL Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi IEINRYEYDTIEQVIVACLDCGDH-TNPKKLFEQLKSKFGKDSV-RVQRIHALCLESNNQLAEALQFESILKK--YPSDASMKRQVAIFKGQGSKAIQVLNAYLQIYMCDLEAWLELSSFHISYSTALYCLEEVLLNAPINIKYAEPLYCYNSAVQYYTHALELNSPAIYGIIMSIYSLAQNNL Dmel DQFRTWRHLILEQVIIAALDTARF-DIATKCTKQLALEFP-GSL-RVMKFKAMRYEALEQYDEADELDAIIAK--DETNAPRKRKIAILKARGLEAIKELNEYLKKFMSDQEAWHELCNMYLAFGKAAFCMEEVLLHNPHSQRLAEIRYTMESARTYYSQALKLNPRALYGIYLCCNHLALEQL Enthi ----------MDKVIIA----GNI-----------NIEIA--------------------------ITEILKK--DPINKAIQRLIALRIQQGDEAISLLQKYNEIYM-ETQAFVQLAELYCTYNDAFDIMQEVVMMEPSNQFAGEIALQVKEARKMFLSACKLSDRALKSTVFV----RLQQL Falba IN-----WSICERVLIAALDRDHFRPIAADCLGRLEKQFGSRSL-RIMRLAGMFEEAKGDFEAAAVYHQILER--DPSNAAMKRLIALAGQLESRMVTLLVDYLEIYMNDAEAWKLLASLYCRYEQAIFCYEQLFVIQETAILCAEALYTLVLARKYYCRALELTSRALQGIFLTSQRLAESLL Fomme1 AKLASFRW--LEQLALAAIDVGNL-DIADECIDTLTECFP-GSP-RVDVLVGIRKEVSLPMEVVLDYDGLLDA--DESNSAWKRKIVVLRRSGAKAVDQLSKFLDTYYTDVEGWLELADIFSSYDAALRSLQHALLLAPQNLQSAEVAYTIPLALKFFLMAIDMTERAWFGLKQCTRHLATERL Fusgr1 EALHLAQWTIYENLIVTCLQTGDD-DSAHLCLERLILRFGGENE-RVMALKGLIKEAEATNNNELSYEDILQQ--DGTNIIAKRRVALLRSMGPEAISSLVSLLEFNPTDAESWAELSDLYLSYSQAIYALEEVIVLAPNAAKLGEVTLMLANSVKRFCRSIELCERGYYGLKKVTDKIATQKL Galma1 QKLASFRWAFLEQLALAAIDVGRL-DIADQCIKQLGDKFP-ASP-RVDVLTGIRIEATEPPSTVLSYDELLKA--NPANAVWKRRISVVRRVGDKAVEELNEYLDTFYTDVEGWLELADMYSSYNSALQALSHALLLTPQNLQFAETAYTIPLALKMFLVVIDMNDRAWWGTKLCSRYLATERV Ganpr1 DLLLLTRFDVLEQIFLASIDNGDT-PTARTALEKVQARFPASESRRSRRLQAMLAEHLGEHERAVEYREMLRAS-DGGDSVRKRLVAALLAQPYEATAELANYCDTFAGDAEAWATLSGVYLEQAQAQYAAEECVLLEPGSLRLADILYTHQGALKYYCRALEVSPRALYGIRQAAGTLATAKL Gloin1 TTLHELRWAVYEQIFIAALDLGND-TLATKCLENLDKRFP-ESP-RVKILKGMKLEAEDNLDAALSYENILQD--DDANVAIKRRIAVYKAKGQQAIEALTKYLDAFYSDAESWLELSALYLSYQQAGFCLEELILLQPQNLKYAEILYTITVALKEFCRVVELCERALLGIKLCTSRLAKERL Hisca1 -----------------------------------------------MALKGVYEEALAKDRDALEYEKVLKE--NPVNVILKRRIGLLRSMSVDAISALVDFLDVFPTDAEAWCELADLYQASMQAIFCLEEALLVAPNAARLGEVEYILADSVRRFCRSIELCDRGYYGLKLSTSRLSTKKL Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 EKLASYRWAFLEQLALAALDVGRI-DVADQCLRQLSDKFP-ESP-RVDVLSGIRMEATEPPSTVLQYDELLKA--DPANAIWKRRISVLRRTGQDAVEELTQFLDTFYTDLEGWLELADIYTSFTLALQSLSHALLLNAQNLQFAETAYTIPLALKMFLIVIDMTERAWWGTKLCTRHLATERV Lenti61 QKLAAYQWDTIEKLTLAALDQGNL-EVADKCLQLLSDKFP-ESP-RVDVLSGIRLEATESTETVLRYDELLEA--DPTNSAWRRKAHVLRQAGERAVEELSAMLDTFYSELDGWLELADIYASHTYALQALSHALLLSPQNLQYAETAYLVPLALKMFLQTVDMTDRAWFGVKLCTRKLSTERL Malgl1 AWLEQQRWAFLEQLGMAAAELGNQ-DLAELCLSRLQSRFM-DST-RVALLKGVIEESHGRLDEAQSYEKLLEK--EPSNLVNKRRLACIKTKPTRATEGLAELVDIYPTDHECWLELASLYLSYSQAAYALEELVLLAPHNLKYAETLYTIAKAYKMFLRILELGDRALWGLKMCTAKLATKLL Mellp23 KELKSIRWDFYEQVAIAALDVKDQ-ELAKSSIDRLEKRFP-GSP-RCLVLHGMLLECNQEFELAKEYEIELKKPIDSKSSIRKRLIALH--LHKEAINLLVQHLDTVYSDPESWIQLAETYCTYDQALSALEDLIILQPDNLRYAETAYTFELAYQTYLRVIELSEK----------------- Mnele DKLRLWRWAVFEQVCVAALDLAKM-KLVNTCIKELAEQFP-SSL-RVSMLEGLKYEYLKKWDDALEYEDMIEY--EPTFPPYKRKVAILKAQNSDAVNDLNRYLNTFSCDHESWLELSDIYISYKQALFCVEELLLQYPHNQRYADILFTLELSCKYYCKAAELNPRALFGIQLASSTLASDMI Monbr AQLREWRWAIYEQVMTACLDLPNRQDLLKSCFEQLEARFP-KSQ-RVERARAMILESEGRYAEALNYESLLEA--HPVDMLLKRRIALNVAQDTKAIKLLNAYIETFSKDEEAWQQLLDLYLAYEKAAFCAEELLLLNPHSTLYAEILYTLLLARKYFAKAVSLQPRALYGLYLACLRTCRRQI Morel2 KVLQDLRWLVYEQVAIAALDMGDD-GLALKCIQALETRFP-GSP-RVRRLQGMQLEAVGKLAEAGQYKAILEE--DETNVASKRQVMLLRTMGSEAIAALVKYLDVNYTDFEGWLQLADLYLDYAQAAFCMEEVLMLQPQNLKYAEILYTIQLALKQFCRVVELCGRGLYGIKMCASRLATERL Mucci2 -----------------------------------------------------------------------------------------------MIEALTNYLDTYYDDHEAWLELCDAYLSYDQAAYCCEEIIILQPSNLKYAEILYTLPLALKHYCKVLELCTRALYGLQLCASKLATERL Mydma QKMKKWRWLLYEQVCIAAFDCNRM-DLALKCLRALDKQFP-KSN-RVLKLKAMRKEVLGQYNDAKQYEVMLED--DPANLIRKRLIALTKIKNEETISALNAYLKDFMADQEAWMELSELYIKFSKAAFCMEEVMLSHPHNQRYAEIQYTMEKARMYFAQALKLDPRALYGLFLTTN--TAERI Neucr2 EALQLAQWATYENLLLACLRTGDD-EAAAKCMDQLEARFGPDNE-RVMALRGLLSEAQAENNGELEYDAILEG--NSTNLITKRRIALLRSMGSDAATALVQLLDFSPTDAEAWSELSDLYFTYSQAIYALEEVLLLSPNAARLGEVQYMLAEALKRFARSIELCDRGYYGLKLVTTRLATAKL Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SALHLAQ-----RLLLACLRTGDD-QSAHTCLNRLSLRFGPSNE-RIMGLRGLYEEATAKDQSALEYDNTLAQ--SPVNVILKRRVALLRSLNSDAISGLIQLLDAIPTDAEAWCELADLYQSGSQAIFSLEEALLIAPNSSRLGEVLYILGRSVQHFSRSIELCDRGFYGLTLVSQQIALVKL Phybl2 EELQSYRWPIYEQIAVAAFDVGDL-ELANHCIAQLRTRFN-EKSLRFKRLTGMKLEAEGKLGQAQAYDSILEQ--DETNMASKRQIALFKERRQEAMEALTKYLDTYYDDHEAWLELCHLYLSYEQAAFCCEELLLLQPGNLKYAEIMFTYPLALKQYCKVLELCKRALYGLDLCASKLAKERL Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 QRLATYRWAFLEQLALASIDIGRI-DIADRCLELLVEKFP-GSP-RVECLTGIRMEASESPEVALQYEGLLEA--DSANAVWKRQISVFRRIGDRAVEELSKFVDTFYTDVEGWLELADIYSAYTHALQSLSHVLLLAPQNLQAGETAYSVPLSLKFFLTAVDMTDRAWYGVKLCSRRLATDQL Polpo LELSDYQYDVVEQVILSLLDCSRK-REAGELIDLLKLKFGKDSV-RVQRLQAMLYECQNVYSRANEYSNILEK--YPADMSMKRQIAILKSNGSQAITLLNTFLQIFMGDFEAWLELASLHIRYRNAAFCYEELILIQPINSKYADIIYSYIVALKYYTHSLELNISSIYGIIMSMYAYAQNEL Pucgr2 DRLKVLRWTVYEQVAVAALDIGNV-ELAKTVIQRLEAKFP-KSA-RVTVLHGMLMEAQGDLLGAKSYEQELEKSFSPKNAVRKRLIALH--LHHTAIQLLVDHLDTVYSDPEGWLQLADIYASYEQSLSALEDLILIQPENLRYAETAYTYELSYKTYLRVIELSDRAALGLKVCIQRLIDEAL Punst1 ERLANHRWAFLEQLALAALDVGRT-DIADTCIGLLNNQFS-DSP-RVDCLKGIKIEATAGPEAAREYESLLEA--DSSNVIWKRLITVYRSQGDKTVEELHQFLDTVYTDLEGWLELADVYDSYTSALQALSHAILLAPQNLKAAETADKVPLALKMHLLVIDMATRAWMGVK------SVRVL Rhior3 EELQQLRWPFYEQVTIAALDTQNM-TLANACDMKH----------KVCWMK---------------HKKYMTV-------CKK-------------------------TKPTCWHQSAKL------------------PY-------------------------------------------- Rhoto1 DELRDTRWDSMEQVVLAGVECGQL-ELAEILSYRLLTHFS-STPHRVAYLRGLLLECKGNLVGAREYEQCLND--DETDVSRKRLIALHLSSPQKGISLLTQYLDTYYADLSGWLTLSTHYASYPQALTALSHAVILAPHDLKFAETAYTVHMAWKEYLRVIEMSTRAAMGAKLNGREVLSRLL Rozal11 -MLATFKLDLFNK--------EKK-EELKRHVEEFDKLFP-NGN-RAKVWYGMINEIEGDSEKAMSYDDILKD--DELYQAIRRKVTLFKNTGDKAIKELNKYLAVYINDEEAWMDLAKF---LPQAAFCLEEVLLLNPKSQLYGEVQFAVQLAITYFKLVLQLKPPALIGLSSCFYSITTTEF Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro EELRELQWGFLEQIFTASLDMPNAEDVRKRCLQALEKRFP-NSQ-RVQRLQAMGFEADGQFQKALDYNEMLEA--DPLNPILKRKIAVHIGKDPLAITALNKYLELYSSDFEAWQQLTDLYIDLQNAAFCLEEVMLSNPHNCTYAEVLFAMTQARRYFAKALELNPRALYGLHLASARTSKEQL Schco3 KTLSDYRWPFLEQFALAALDIGRF-DVADDCIRELSDQFP-DSP-RVNILTGIRMEATESPETCLKYDDIQDT--ESPNPIWKRRISVLRRAGEKAIEELCQLLDTFYNDLEGWVELADMYSSYTPALQSLSHALLLAPQNLQFAETAHSIPLALKMFLIVVDMCDRAWWGVKLCARQLATERV Schpo1 VALFSQQWDVYQKVFIAALTTGET-VLAKKCWNRLNDRF-HKSP-RVEGLYGMFLEATASEKDAMSYNSKLSE--DPTHTIYKRKLALLRSMGKECIQGLINYLDTFYNDLEAWAELADIYVSFESAIFCYEEMVLLQPFEARLGDLYFVWF-SLKHYCRSVEICEHGWFGISKCCQQLSLKK- Sorma DAVGFTCWKTGSQVVLSHVTGGID-----LCLPALKARFGADNE-RVMTLRGLMSEAQAQGNGELEYDAILEG--NSTNIITKRRIALLRSMGSDAASALVQLLDFSPTDAEAWSELSDLYFTYSQAIYALEEVLLLTPNAARLGELQYMLAEALKRFARSIELCDRGYYGLKLVTTRLATAKL Sphar -----------------MLDT--------------------TTP-----------------------------------------------------AELNKYLAVFITDYEAWMELVDLYLELELASFCLEDVILSHPHDTLHGEIMYAYKTARQLFSKACESNPRAHYGLFLSAARHARDKL Spipu1 QKLATLRFAVLEQVFVAALDTGNI-DIAKTHLATIEKRFPFKSSVRVQRLYGLLKEAEGDFDKAIEYQTALEQ--DEINVTHKRLVAVLSSQGTEAIERLVTYVDAFMQDVEAWAELASLYIGYQQAAFCFEELLLLRPQNIRYADLLYTLDLAVKYYCSGLELCKRALYGLRLASSALSGDRL Sporo1 ----------MQLI-------------------------------------------------------------------RKRLIALHLASPVQGIKLLVEYLETTYIDAEAWVLLSKSYSEYEQALSSLNHALILQPQNLNHTEVAFTFEPCLKQYLRVMEMTTRAAFGAKSDGMHKLS--F Stehi1 QRLANYRWSFLEQLALAAIDVGRY-DVADECLKRLAEKFP-ASP-RVDCLQGIFLEGTQSPQLALKYGKLLET--DPANAAWKRRISVLRRLGETAVTELTQFLDTFYNDVEGWLELADIYTSYTLALQALSHVLILSPQNLQAAETAYTIPLAIKWFLLVVDMTTRAWYGIALCSRRLARDVL Tapde11 IELRRMRWDIYEQSLVAALEVADD-ELALTCLTRLSDKFP-QSG-RVHALRGMLLEATQDPQEALTYKEVLEV--EPTNVIRKRQITFEKSLGVEAVAHLVQYLDVYYTDGDAWAELGDLYTSFDRAIFSWSEALILKPHDASYADALYALHTALKSYLRSLELSDRSVCGIKMCCDHISLKWL Thetr AALAHIRWDVLEQVAVAALQTEMV--LASQCIRRLAKKF-RDSD-RVRILIAMKHEAEGDVQVAVEYREIIEA--KPNSPAYKRLVAAHKGAGTAAANTLATYLETYMTDAEAWAELAELALEYGRAAFCYEELILLEPYNLLYAEVMYTLDIALAYFAQAVELSPRALTGLLMAAARLARDKL Treme1 ERLAQWRWAVREQLVIAALDVGRI-ELASEQIDILEKKFP-ASP-RVLLLKGLRLEAEDQPVAAKKYMAVLAT--DETNVAHQRLIAVSLSTTPTTIPVLLTYLDNFYSDPSAWSLLADLYCRYAQALTAMGHLMLLQSWDTKAGEIAYTYSLSLKYFLRAVEMENKAWWGVKQVRKLLATERL Trire2 EALQVAQWTIYENLLLACLRTGDY-TTAHQCLERLVIRFGGNDE-RIQALKGLVKEAEATDNSELEYEAILAN--DNTNVISKRRIALLRAMGAEASEALVQFLDFATTDAEAWIELSDLYLSYAQAIYAQEEALVIAPNAARLGEMLFMLAESLKRFCRSIELCDRGYYGLKRVTDKLATKKL Umbra1 LELQQYRWPFYEQAVTAALDVGDF-RLADECIENLKRRFS-SSS-RVQRLVGMRYEAEGKLADAQKYDAILEE--DESNIVSKRQIALLKLRGSEAISALVTYLDTYYSDAEAWIELCSLYLSYQKAAYCLEELILLQAANLKYAEIMYTYSLALKQYCRVIDLHERAMYGIQLCASKIATERI Ustma22 QWLAEQRWSILEQVAIAAIEVARF-DLAELCISRLSSRFA-NSQ-RVTSLQGMLLEGQAKSRDAIRYESVLET--EQTSLLSRRRIGAIKSTGKQTLHALNSHLDIFYNDPEAWQELAEVYATYAQSAFALEELLLQVPQNLKYAETLYTLTKSYKAYLRVLEMCQRALWGTKMVTTALVTKLL Walse1 EKLEEFRWAFYEQYAISALDVGDH-LLAEELLLRLAEKFP-QSP-RVSVLEGMLLESKGEFRLAERYTSLLEE--DP---IQKRMIVLTKLLH-KALDRLTTYLDTFYSDPEAWMELADIYTQYQRALFAIEECLLMQPINLKYAETQYTIHEAYKSYLRVVELQDRAWLGLKMCCKKLSTKKT Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2440.fasta_al_trimmed; alignment length = 87] Allma1 MVRYKYRYLVFSVSVTASVMIRATASNLGVKYFSGF-TGIGIVRVARDHYRMLWATLTFL-NAIVVLHCSGTIRKAQQAALEDRVML Ashgo11 MVRLKSRYILFEILITQKSILRKVLAILQVKYFSNK-TSTGILRCSREHYQLVVMALMLM-KRINPVKVSGTIKKIERYAIRNQQLM Aspfu1 --------------------------------------------------------------------------------------- Aurde31 MVRFKNRWLLVEFILDAKRILKQSIPSLTVKYFSPT-TRMCIIRVARDHHRIAWAGLTLL-STVHVVHLSGTIKHTQLAAIQNKIVV Batde5 MVRFKNRYLLCEII----QIIKESLISLQVKYFNPF-TGLAIVRVNRDYMRLVWACVSLI-TAIKVVHVGGTIKLVQSQAIKNQTII Botbo1 MVRFKNRWFLVEFIVSSKQILKDSVGSLNVKYFSPV-TNLCIIRVGRDNHQIAWGAITLL-TTLHVVHCSGTIKKVQQAAIRNREVV Botci1 --------------------------------------------------------------------------------------- Caeel --------------------------------------------------------------------------------------- Canalb1 MVRIKHRYILFEILINVKTIIRKSLMLLNVKYFSNR-TSTGILRCGRDQSDYIIGAMSLI-EKMRCLHVSGTIKKCEEYSIETKQLI Cangl MVRLKSRYVLFEIIINSKTIIRRVVSLLHLKYFSNA-TSTGILRCHREDLNILLTTLALV-NKINPVKVSGTIKKLEQYAIRNHNFI Capow MVRFKNRYVLGELTVSIGPLLKDAVGSFNVKHYNTE-TGLTMIRAPRDYVEILLSSLTLL-GTIKTVHVSGTLRKSRVAAVEHRRQL Catan2 MVRFKYRYLTFILTLQAYDLIRAATSNLSVRYFSNF-TGIGVARVARDQIRYLWSTLSLM-TTIVVVNCSGTMRKAQEAAI------ Cioin --------------------------------------------------------------------------------------- CocheC53 MVRVKNRYLVVNFLLKPGFIIRDGVSGLKVNYYSPS-TSTAIIRCPRDHYEMVWAALTYT-TRLQVVRVSGTIKKAEEEVIRSQLII Coere1 MVRFKNRYICFELLTSAKGILRESITGMQVKYFNKR-TQMGIVKVPRDHCNMVLAAMVVI-THARVRHVSGTIKKCQQSAIRARELI Conco1 MVRVKYRYLLIQIELTDVQLIFNTVGSFSVKYLSKE-TGLAIIRVTRDYYKELATCLTLI-NQLTILHCSGTIIKCQRSAIKNKELI Conpu1 --------------------------------------------------------------------------------------- Copci MVRFKNRWLLVEFILDGKQILKQSIAGPPVKYFSPT-TNTAIIRVAREHHKIAWAGLTLL-STINVVHLSA---------------- Croqu1 MVRFKNRYLLIELILNEKILIRSSISSLTA--------------------------------------------------------- CryneH991 MVRFKNRYLLVEFLEGGQGIVRSSVSSFRVIYHSPL-TTLTFLRIARPHYRLLWSALTFM-T--RVIAISGTIKKLQNRGIAHRAMV Crypa2 MVRVKERYLLINILFTARTFIKAEIRTMRIKYLSNA-TSTCILQCSRDHYRLVWAALTMM-DRVQVVRVSGTIKKVEQEAVR----- Debha1 MVRLKQRYILFDILISQKTLIRTVIMQFAIKYFSNK-TSTGIIRCGRLSFQIVVAALALM-NKLRCIHVSGTIKKCEEYSIKNRDLM Dekbr2 MVRLKTRYILFEIIVTGRQIIRSSLG-LSMRYFSPR-TGTGILRVTRNNWKYIVAAITFI-NSIHTINVSGSIKKCEDRSMQSNDLI Dicdi MVRLKNRYLMTEVILSDSWLISNEVKTLKIIYVNPD-TNIFIIRVSFEYYKSLWTALTLI-TSYRMVHVGGSIRLCQKAAIKGKQIS Dmel --------------------------------------------------------------------------------------- Enthi MVRVKSRYLLIHAVIAKGEFIVAGVK-TGIIYTNWLKTGIVIIKCRFERLNMIKTTMKYFGSERNVVHVSGTIRSCKREAIK----- Falba MVRVKHRHLLIRFYVLPHHVVRDAVKGPSLLYWNPG-TGRAIVRVAREAAAPVRAAITLA-APMRVVHIGGTLKSLLQAGRELRRTL Fomme1 --------------------------------------------------------------------------------------- Fusgr1 --------------------------------------------------------------------------------------- Galma1 MVRFKNRWLLVEFILDGKAILKQSVLSLTVKYFSPT-TNICIIRVGRDQHNIAWGALTLL-TSINVVHVSGTIKHAQLSAIANREVI Ganpr1 MVRVKNRWILFNLQIHAGTVLRDTVGGVNVKYYNPL-TGLGILRCLRDNHRLVWAALTFV-SRIVVIRVCGTVKKCQMAALRDRQGL Gloin1 MVRLKNRWLLFEVILSTRDVIKNSVASI-IKYFSPF-TNIGVLRISRDHYHIVWGAMTFI-TQIRVLHLGGTIKQCQLSAINDRDQI Hisca1 MVRLKHRYLLVDILLTPQSLVREHVGGVSVKYLSPA-TSTAIIRCPRASYRLVWCALTYM-SRIRVVRVSGTMKKAEQEAIAARREV Klula1 MVRLKSRYILFEVLISPRNILRKQLALLQIKYFSNR-TSTGIIRCGHDDHQYVIMALALM-NQINPIKVSGTIKKVELFAIRSHRLN Lacbi2 MVRFKNRWLLVEFILDGKIILKHSILSLTVKYFSPT-TNICIIRVGRDHHQVAWAGLTLL-TSINVVHLSGTIRHAQLAAIANREVI Lenti61 ----QNRWLLVEFLITSKHILKQSVSSLTIKYFSPR-TNLCIIRVARDPHKIAWASLTLM-ATIHVVHVSGTIKQAQLAAIRNREVV Malgl1 MVRFKNRWLLLTLAVNAYSIIRASLGPLTCKYYSPK-SGIGILRSSRDGVRQVWAATTLL-NTICVRSCGGTIRKVQRKAISDKTCI Mellp23 MVRFKNRYVLINLMLNSKEIIRHSIASLNIKYYSPI-TSLLILRCSRDSISIVRVALMLI-RQIQSINVSGTMRKTQEAAIRDRELV Mnele MVRLKYRYFLTSLHLTSETLIYNSIGRVKIIYLALL-SGTALIRVPADFEKQSRVSLSSL-VVVNVIHVGGTIRSCQKQLVKNVNSL Monbr MVRFKNRYFLVELCMTPKRLLRTAIHTLNCKYLNMA-TGAAILRCAKDVEEILATTMPLL-RRLRTLSRAGTIASCRKALLSNRTKL Morel2 MVRFKNRYLLFEIVLANKDLLKDSIRPLTLKYFSPH-TNVGILRISREEMHIVWGALTFI-NQLKVIHTSGTIKKCQLTTIKDRDRI Mucci2 MVRFKNRWVLFQIVATDSMIIFQSI-SVAVKWYNAT-TRIGILRIPRDFTDMYLSSMFFI-KQVSILHVSGTVIFIQQAAIDDRRFY Mydma MVRKKQRYFVVEIILSREDIIRLSILNLFVKYVNPY-TKLFFVQAPREYQIIIRACLTFI-KMLNCIYVAATIKSAEVFLLKDKETL Neucr2 MVRLKDRYLLVNIVLRPQTIIRSQVRSLQVKYLSTA-TSTFILRISRAHYRLVWAALTFM-DRLRVVRVSGTIRKVEEEAIRAKLLV Orpsp11 --------------------------------------------------------------------------------------- Pench1 MVRLKNRYLLVDILLTQGFLIRDSVGGITIKYLSPA-TSTAIVRCPRAAFRLVWSALTYM-SGVRVLRVSGTMRKAEEEAIRARREI Phybl2 MVRVKSRWLLFEIVITEEHLIRETIWNTSVKWFNST-TRTGIMRVGREYVDLVMGSLFFV-KQINILHSSGTLISIQKTAIEDRSFY Picst3 MVRLKQRYILFDILINHRTLIRKSILLVSIKYFSNK-TSTGIIRCGRLTFHTVIGALSLI-DSIRCIHVSGTIKKCEEYSIRSRDLM Plicr1 MVRFKNRWLLVEITLNPSQILKLAASSLTVKYYAPL-TRLAIIRVARDAHREAWAALTLL-RAIRVVHVSGTIKHAQLAAIENRIAI Polpo MVRLKTRYLMVEVILSLSWIIEQKSKSLKIIYCNSI-TNTMILRCNFEQYRNLWTVLSMI-TECRVLHVGGSLKSCQKSVLKGKPLL Pucgr2 MVRFKNRYLLIQLIVNEKSLIRQSIADLTVKYYSPT-TSNLILRCKRDQVTKVRASLLFI-NQINVIHVSGTIRKTQSFLIEDRQQI Punst1 MVRFKNRWLLVEFILNGKLILKQSVYSLTVKYYSPT-TRLCIIRVGREHVRTAWGALTLL-NSINVIHVSGTIKHAQIAAIENRVVI Rhior3 MVRFKHRWILFQVILTDQMIIYNQV-SIA-----------------------------------SILRVSGTIIFIQTAAIEDREHY Rhoto1 MVRFKHRYLLLHLLLSESSLLRDSLGTFSIKYLSPS-TSTVIIRISREHFRTLWAALTLL-RKVRVVHVSGTIRKTQHAAIADRTQI Rozal11 --------------------------------------------------------------------------------------- Sacce1 MVRLKSRYILFEIIVSIKSIIRRSLSLLQLKYFSNK-TSTGIIRCHREDCDLVIMALMLM-SKINPVKVSGTIKKIEQFAMRNSKIL Salro --------------------------------------------------------------------------------------- Schco3 MVRIKNRWLLVEFLLSEKTIVKQSVVSLSVKYYSPT-THMCILKVGREYHNTAWGAVTLL-TAIHVVHVSGTIKHAQMAAVTNRAVV Schpo1 MVRFKSRYLLFEVLITTSSLIRTMVSSLTVKYFSPN-TSTGILRVSRQHFRLAWAALVLI-RELRVVRVSGTIKKAELAAIENKSEI Sorma MVRLKDRYLLVNIVLRPQTIIRSQVRSLQVKYLSTA-TSTFILRISRAHYRLVWAALTFM-DRLRVVRVSGTIRKVEEEAIRAKLLV Sphar MVRVKLRYLLVKIHLTWKNLIIAALQWLQVKYVDPE-LGVAIVRCGRPQFLLVSTAMTTI-ISLRVCHVSARTTGVIDALT-QRVRL Spipu1 MVRLKNRYLLFNLHINGGTILKDSLASFTVKYYSPH-TQTGIIRCARESYQMLWAALSFI-TKICVVHLGGTIKSVQQVALKDREAL Sporo1 --------------ITESAILRDSLGTFSIKYLSPT-TMTMIIRVSREHFTTLWASLTLL-RRIRVTHVSGALRS------------ Stehi1 MVRFKNRWILVEFLLTGQRILRQSIASLSVKYFSPT-TNLCIVRVARDPYRTAWAGVSML-SNINVIHVSGTIKHTQLAAIENRTII Tapde11 MVRLKHRYILFEIR--QKDLIRQSLASLYLKYYSPR-TGRGILQADRAHYRLAWAALTFL-DLLCALGVSGTIRKAEERLIGDRRQM Thetr ---------------------------MAVPFYNPL-SNTAIVRAPFDHFRMVWAALTLT-TELRVIHSAATLTNCRELIIKNRALL Treme1 MVRFKNRYLLVEFLDGGQVITRNQISSFKVIYHSPL-TSLTILRIARPHVQTLHTGITLL-SLTRVIGLSGTIRKCQNRAIAHRWVV Trire2 MVRIKERYLLVNIILTPQALIKAEVGNLSVKYLSLA-TSTFILRCNRAHYQLLWSALTFM-DRVRVVRVSGTIRKIEEVAVEARKLI Umbra1 MVRFKNRWVLIEILITAGMLLKDAISSLNVKYFSNH-TNIGILRVSRDYHQMLLVSLFFI-KEITVRHIGGTILKAQRAAIQDLETL Ustma22 MVRFKTRWLLLAIDLTPQLILRASLGVLTCKYYSTH-TGTAIVRCSRDAARLVWASATMI-ARPRVVHCGGTIKKVQNKAIEDRKLI Walse1 MVRFKNRWIIAEIILDGKQIIRRNINSLSLKYHSAI-TRLCIFRIAREYKDMLHAALTLT-TSLRVLHVSGTIRKVQEAAIRNREAI Zygro1 MVRLKTRYILFEVLISAKTIVRRSLSLLQVKYFSNR-TSTGIIRCHREDTDLVLMALCLT-NRINAVKVSGTIKKVEQYAIRSQRFL [Cluster2455.fasta_al_trimmed; alignment length = 96] Allma1 GQWSLSSAAPKHGLQLHAPNTDLFWQSFPHRVEVVALFLDDETWTPHIVQVQAGADVGDPVTLTHP-HGWVLILRIRIVETHQQGRNCQVRGVRVF Ashgo11 AYWKPSSFKAGYPIEALDDNPATFWQSFSKRVDILAMYFSDESYTSETLRIYAGHDATYYKTLENV-NGWVKFLRIEVVTNHENGKDTHLRGIRMF Aspfu1 ------------------------------------------------------------------------------------------------ Aurde31 GTWSVSSFKFGFGTELRDDDPGTFWHSFARRVAIIALYIADDSYTPQALLLRAGTDLQDVRTIAKP-TGWVVFIQVVVMENHMKGRDTHVRGMKVL Batde5 AKWSLSSNKEAFGVDLHDGNLDTYWQSFHKCWAIVSVYLDDESYTPRQIALRVGNDLYQISQLEEP-SGWIDILQLLVLSNHQGGKDTHVRQVKIM Botbo1 ATWSVSSFKYGFDVELRDDDPETFWQSFSKKVKVIAILLDDDSYTPTRLTIRAGTDLQDIKNVNSP-SGWITFIQVMIAANHLNGKDTHVRGLRIL Botci1 ASWTVSSSKPGCGVLLRDDDTNLFWQSFAKFAKIIRIFLDDESYTPTRIQLLGGTDLIPFSELSQP-KGWIDVIQVKVLENHQNGKDTHVRGLKIY Caeel AIWALSSCKSGFGIDLLSDSVEKYWQSFQKKTDVMMFYLDDESYTPSKIQVKMGSDIFFRQTQTEP-QGWTFILQVQVIQNHQNGRDTHIRHVRVL Canalb1 ATWKLSSWKQGFGLKLRDDSPDSYWQSFSKKVALISIFTNDESYTPSRIKIMAGSDLIEVCTVNQP-VGWSHIIKIIILANHQEGKDSHIRAIRCF Cangl AYWKASSCKTGNPITAIDDSFENYWQSFSKRMDIIGIFFTDESYTPRVIHIFAGNDAVFYKTLINM-NGWAALLRFKFPVNHENGKDTHLRGIRVY Capow GMWSVSSAKHGCGMQMLDNTPTTYWQSFEKRMAIVWLYLNDESYTPSKITLAVGTDLEECSILSQP-DGWVCFFRMFITANHDNGRDSHVRQVKLM Catan2 GLWTISSGRTDPNDELDTDNLETFWTTFPKIVHVLELYLDDLTWCPRLISCIV--DEDRFTFSK---VGWQSFVKIMFEQNFSNGQNMRLRGLKLF Cioin AVWSVSSCKQGYGVNLRDNSLETYWQSFKQKTTIVGVYTDDESYTPSRLSVSVGNDLSEVEQVEEP-SGWVWIAQISVLQNHQNGRDTHMRQIKVF CocheC53 ASWTVSSSKPGCSIPLRHANTNLFWQSFFKLVRILRLYLDDESYTPTRIIFLAGSDLQEWGEMRSP-RGWIWATTTNILENHQNGKDTHLRGLQVF Coere1 GIWSASSTKHGFGINLYNNNIETFWQSFPTRQHILSLYLDDESYTPCKVCIFSGTDMQLLQESDEP-RGWIDFLRIELPLNYENGRDVRVRQIRIL Conco1 CKLRVSSYKYGYPPTMIDNSLETYWQSYSRQILLLKIYFDDESYTPNLFTISLGNDYKELTKVKQP--KWIEVIKLTILNNMEDGRDSHLRQIRIF Conpu1 ARWSVSSYKFGFGAELRDGDPETFWHSFPRKVAIISIYLSDDSYTPSTIAVRAGTDLQDVRVATKP-DGWITFLQVIVVANHMSGKDTHIRGLRIL Copci AKWSVSSYKFGFGVELRDGDPDTFWHSFPCKVAIISILLRDDSYTPSTLAIRAGTDLQDVRMVTKP-DGWITFLQIIIAANHMSGKDTHVRGLRVL Croqu1 AVWSVSSAKPGFGVALRDDSIHTLWQSFPKKTAVISIFVDDDSYTPCRLSIAVGSDLQVIKLVENP-RGWQDIFQIAVLANHLNGKDTHIRAVKIF CryneH991 AQWSVSSHKYGFGVDLRDDNDNTFWQSFPRKVMI------------------------QVRYLEKP-DGWHLILRIVIFANHLNGKDTHVRGLKVF Crypa2 AHFRVSSFKPGNGVELVSDDTDRYWQSFVKCVEILRFHVDDESYTPTRIMWYAGTSLMHFATSNNP-EGWTDVVQMQIIENHQNGKDTHIRGVKIY Debha1 ANWKLSSSKQEFSLSLRDDSSDSYWQSFSKKVSLISIFTNDESYTPSKIRILAGTDLSEVCTVNKP-IGWSHIVKLVILANHQDGKDTRIRAVRCF Dekbr2 ATWTASSFKPGFGTKMREDSPLSYWQSFSKKVSIICMYSNDESYTPSKILILSGSDSVEVASREEP-VGWQHVIKICFLSNHQNGKDTHVRCIKVM Dicdi ASWSVSSAKPGSGVELRDNNLDTFWQSFPKKCYILLIHCDDESYTPCKISIKAGTDLQEIILTEEP-SGWINILQISILSNLKNGRDSHIRQIKVY Dmel AVWSLSSCKPGFGVELRDNIMDTYWQSFHKRTNIIYIYTDDESYTPSRISIRSGTDLQELQVMDEP-TGWVQILQIAVISNHQNGRDTHMRQIRIH Enthi ----VSSSRIGFGVSICDNNISTYWQSFDEPQTLVRFYVSDESYTPSKVVLRVGTDLIELAVVTEP-EGWYYLVQLVIQENCSHGRDSHIRQVQIF Falba ARVRVTSWRRGHGAALTDGSPHTFWRSFPRPFRLLAVYVDDESYAPSQIAVRLGGDLVTISIIDDAHQGWVVAVHLMVVKNHFGGHDTHLRQVRVF Fomme1 AKWSVSSYKFGFGPELRDGDPDTFWHSFPRKTAVISLHLSDDSYTPSTICLRAGTDLQDVRVVSKP-NGWITFLQIIILANHMNGKDTHVRGLRIL Fusgr1 ARFTVSSHKPGNGVELKSDDLKQFWQSFTKRVGIIRFFVDDESYTPTKVVFKAGTNLIEFATMTNP-VGWQQVVQMQILENHQNGKDTHLRGIKIY Galma1 AKWSVSSFKFGFGAELLDGDPDTFWHSFPRKVPIISIHLNDDSYTPSTLAIRAGTDLQDVRVVTKP-DGWITFLQIIVAANHMSGKDTHVRGLRVL Ganpr1 ATWVLSTYKPGMGVELRDGNLETFWQSFPTLAFIISLFLDDESYTPSRFAVFAGYDLEEVRAVEEP-CGWVEVLQLAVLANHANGKDAHVRLVRVF Gloin1 AIWSLSSWKHGNGVDLRDDNFLTYWQSFPQKVNVISLWLNDESYTPNKITIRAGTDLQDLRTVEEP-LRWVDIFQIAIKANHQNGKDTHIRQIKVF Hisca1 ------------------------------------------------------------------------------------------------ Klula1 AFWKASSFKVGNPIAAIDDDPTTFWQSFSKRVDVLAMYFCDESYTPELFKVYAGYDASLYRTFENV-NGWVVIIQIQILSNHENGKDSHLRGIKIF Lacbi2 AKWSVSSFKFGFGVELRDGDPDTFWHSFPRKVAIISIYLNDDSYTPSTLAIRAGTDLQDVRVVTKP-EGWITFLQIIVAANHMSGKDTHVRGLRVL Lenti61 AKWSVSSFKFGFGPELTDEDPDTFWHSFPRKVSIISMYLSDDSYTPTTIAIRAGTDLQDIRILTKP-DGWITFLQIIILANHMNGKDTHVRGLKVL Malgl1 VSWMLSSAKARHGIALTSDDLDTLWQSFPRRTPVLSIYLDDDSYTPTKILVKAGTDLVDVRYRQ---------LQVCILGNHLNGKDTHIRCLKVF Mellp23 AVWSVSSAKPGFGVALRDDSIHTLWQSFPKKTAVISIFVDDDSYTPCRLSIAVGSDLQQIKQLDNP-RGWQDIFQIAVLANHLNGKDTHIRALKIF Mnele ------------------------------------------------------------------------------------------------ Monbr GVWSLSSRKLDFGIRLRDGRDETYWQSFSSRRKFMALNTSDESYTPKVVEIRAGPNLTEVVTADMN-EGWFYIIQLAVLVNHQNGKDTHLRGVRIY Morel2 AAWSVSSAKAGHGLELRDNDLDTYWQSFEKRTSIVSFFRDDESYTPLRVSIRGGTDLKELYSLDEA-TGWVNILQLAVLSNHHGGRDTHVRQLKLF Mucci2 AIWSVSSFRPHWGPDLRDNNALTYWQSFHQATFIVSIFIDDESYTPKTIMVRGGTDLQELGRVEEF-VGWVNILQIAILNTHLNGRDTHIRQLKVY Mydma AVWSLSSCKPGFGVSLRDNKLTTYFQSFPWKQAVVSIYTDDESYTPNRISIRVGNDLKQKELLEEP-CGWINVIQIAVLGNHQNGRDTHLRQIKVF Neucr2 ------------------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------ Phybl2 SLWSVSTRRLPWGVELRDNNPLTYWFSFSKPTWIVSLFIDDNSYTPWIVSIRGGTDMQEIMQIEKT-VGWQHALQIAILSTHENGRDTHIRQAKVY Picst3 ANWKLSSYKQGYGLPLRDDSPDTYWQSFSKKVSLISIFTNDESYTPSKIKILAGSDLNEVCTVNKP-IGWSHIVKLIVLANHQDGKDSHIRAIRCF Plicr1 AKWSVSSYKYGFGAELRDGDPETFWHSFPKKVAIVSVFLSDDSYTPSTLAVRAGTDLQDVRVVTKP-DGWITFLQVIIAANHMSGKDTHVRGLRVL Polpo ATWTLSSAKPGFGIELLDENLSTYWQSFNRRYEILLLYTDDESYTPSKISIKIGSDLEEIINTDEP-NGWINILQISIIANHQNGRDTHVRQIKVL Pucgr2 GLWSVSSAKPGFGVELRDDSVHTLWQSFPKKTIVISIFVDDDSYTPCKLSISLGTDLQVVKIIENP-RGWHHIFQVAILANHLNGKDTHIRCLKIL Punst1 AKWSVSSFKYGFGAELIDNDPDTFWHSFPRKMAILSIYLSDDSYTPSTLAIRAGTDLQDVRVLTKP-DGWITFLQIIIVTNHMNGKDTHVRGLRVL Rhior3 AIWSVSSFRPHWGPELRDNNPQTYWQ---------------------------------------------------------------------- Rhoto1 AHWAVSSAKPGYGVEVRDADPATLWQSFPKKQSIVWIFADDDSYTPHKISIRAGTDLHEVRWVENP-RGWQAFVQIAILSNHMNGKDTHVRGVRIF Rozal11 AHWMLSSRKMGFGVELRDDQVETFWQSFSRKTSVLAVYLDDESYTPQKILIRAGYDLQDVCQKEEP-CGWTLFEQ--------------------- Sacce1 ALWKPSSFKLGNPVDALDDNYDTFWQSFSKRMDIMAIFFSDESYAPSLVKVYAGHDARFYKMLENV-NGWVALIRLLFPVNHENGKDTHLRGIRLY Salro GVWTLSSCKAGFGIQLRDPSTTIYWQSFLQRTALFSIYVDDESYTPKTLSVRVGSDLREVKVVNAAVQGWRNILQVAIIANHQNGRDTHLRALRVH Schco3 AKWSVSSFKFGFGAELTDGDPDTFWHSFPKKVAILSLFLSDDSYTPATIEIRAGTDLQSIQIINKP-DGWITFVQIAILANHMSGKDTHVRGLRVL Schpo1 AQWTCSSEKSGFPIRVRDDNIDTYWQSFVKRVSIVSMYLQDESYTPSTLRISAGTDLEIVTTVQEP-TGWVHVIQIKILANHQSGKDSHVRLIKIY Sorma ------------------------------------------------------------------------------------------------ Sphar AVWTLSSCKQGFAMDLRDGNLDTYWQSFPKRQTVVCFYVDDESYTPQKISVKAGSDLREITQMSEP-SGWVSVLEITMLSNHQNGRDTHMRQIKVF Spipu1 ARISVSSFKEEHPPEMMDGSTDTYWQSFPQLMTLLSIYVDDESYTPSVVAIRAGNDLQDLHRYEEA-SGWVDFVQLCILGNLQNGKDTHIRQLKIF Sporo1 GSWAVSSAKPGYGVELRDNDTETFWQSFNKKHSSVWMYVDDDSYTPHKISLRAGTDLHEVKWIEQA-KGWQPMVQIAIISNHMNGKDTHVRGVRVY Stehi1 AKWSVSSFKFGFGPELQDNDPDTFWHSFPRKMAVISLFLSDDSYTPAALSIRAGTDLQEVRSLVKP-DGWITFLQVIIITNHMNGKDTHLRGMRIL Tapde11 GSWTVSSAKPGFDIAVQDASLDTYWQSFPRLVTFLSIYLNDESYTPSSIRVMSGMTLLEVQTLDEP-TGWHHVVQLQVLANHQNGKDTHVRAIKLH Thetr AAWSLSTAKTGFPVDLRDGSTETYWQSFPKKMAILALHVDDESYTPRTLSLRIGTDLVELEVVEQP-AGWVVILQVAVVSNHQNGRDTHIRQMRVF Treme1 ATWSVSSHKYGFGVELQDGNENTFWQSFPKRVFIIALHTSDDSYTPSKLSIRAGTDLQEVMFKEKP-DGWLLILRILVLANHLNGKDTHVRGLKIF Trire2 GKFTVSSHKPGNGVELRSDDLTSYWQSFVKRVGIIRFYVNDESYTPTKIIFKSGTNLIQFAAMNSP-VGWQQVLQMQILENHQNGKDTHLRGIKIY Umbra1 AVWSVSSFRPDWGVELRDNNPLTYWQSFHRATIIVSIFVDDESYTPKQISIRGGTDLQEITLLEDQ-TGWKNALQIAVLSTHQGGRDTHIRQIKLY Ustma22 TQWTLSSYKPGSGVALRSSDLTKLWQSFSRRTCVLSIYLDDDSYTPTKIAVKAGTDLTMVRQRTAP-QGWKHFIQVCILANHLNGKDTHIRRLIVF Walse1 AQWSVSSYKEGNVLDLMDTNPDTVWQSFTRRVSIVSMYLDDDSYTPKTISIRAGTDLQEIRHIDQP-RGWHHFLQLAILTNHLNGKDSHIRGIAVF Zygro1 AHWKPSSFKMGNSIDALDDNPDTYWQSFSKRIDVIAFYFSDESYTPRLIKIYVGHDALFYKTLENV-NGWVALIRIVFPVNHENGKDTHLRGIRIF [Cluster2458.fasta_al_trimmed; alignment length = 346] Allma1 QLNTATIAPFLDRQLLVPVLRHLRDVLEQLFAVV-S-ATANADLASQIADEIVKARSAETLNNVDEDVSNILDVLA-AAAHDRVSNSNYVQDVTVDAIDKVFHYGQLYYQAGQYAKAAEILD-QYRRISAAMWGKLAALIL-ANDD-GASDALHRLRDAVENALQQRAWLLHWTLFVHLRTETGLPVQEFF--YQNVVETACPWLVRYVVAAAALTTRDAARLAAQEDPVASVLENLLVSVDLDAAADALEAVAKADYFLDALVAALRKQVFQVLANVYTQLPVAQAVLHV---DDFDWQSVAT-----------DVKGGVTPARRGVLEKMDKLSHRSDNTMAML Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 NL-LPKLIPYLDRHLVFPLLEFS-EIVRAKYELL--KHTNMTDYVANLWKEIFVKKREEVLQQYEEESAKITQLLQDESVSDKVANLKFLEEVTVEMVNSLYDYGRFQYSCGSYGNAAELLY-QFRVLSSATWGKFASEIL-TTSWEAAMEEVQKVKDSIETRLQNRSWLIHWSLFPFFNHDPARDLTDLFPAYINTIQTNCPWILRYLAAAVITNLKDLIRVVRQEDPITDFIKALYVDFDFEEAQKKLEEVLRSDFFLDAFVEAARHLISESYCKIHQRIDILSTRLGLNQDEGEKW--IVNLIRDTRVDAKIDYKEGTVSVYQQVIEKTKGAFFRTQVLSAAV Aurde31 DL-TQTIIPYLDRHLALPLLAHLEQVRQAQYEVA--KGTNMVDYAVSLFQQLFAEKRDKALERLQQEAQAVLDVIENPEVQDKAQNLQYLKEVTLDQIAALYNFGQFQYTYGNYSGAADYLY-HFRVLSSAHWGKLASDTL-SGKWDIALEELNALRDAIDARLQSRTWLLHWALFVYFNHPQGRTLLETFPVYLNTIQNSAPWILRYLAFAAIVSLREIVKVVQTEDPLTAFLKELYVEFDFEGAQRALEAVVENDFFLDDFLENARYLISEAYCRIHQKIDILSERLNLSRDEGEKW--IVNLIRETRMDAKIDLEKNVIPIYQSVIEKTRGMAFRTSAIGAAI Batde5 DL-TLKITPFLDKHLILPLIEFQKDLLKSKHQLL--STTKMMDFTNTVYKELYDKRREHVLDDLEKQVNPCMNIIQDPTFQDKVANLTLLKDFKPEMLDVLYKYALFQYDAGQYVIASDYLY-HFMALSSALWGKLAADIM-ARNWDGAYGELISLRETIDQSLQQRMWLLHWSLFVFFNHPRGKDLIDLFPAYLNAIQTSCPWLLRYLAAAVIINLKDLVEIIKQEDPITEFLISLYANFDFDGAQQKLEAVFSNDFFLSEFRESARLFIFEMYCRIHQHIDILCDKLNMDSVEGEKW--IVNLIRDARMHAKIDSESNTVSVHQQVMERTKALSFRSSLLAFNI Botbo1 DL-TQKLIPHLDRHLVFPLLNHLEQVQQAQYELA--KGTNMVDYAVGLFNQLYAAKRDNAVDRLQQEAQAVLDVIENPDVQDKMQNLQYLKDLTLDQITALYNFGQFQYTYGNYSGAADYLY-HFRILSSAHWGKFASDIL-TGKWDSALEELNRLRDVIEGSLQSRTWLLHWSLFVYFNHPDGRQLLDTFPAYLNTIQTSCPWILRYLAAACIISLQNIVKIIQTEDPITNFLRELYVEFDFEGAQKWLEKVLDNDFFLTEFMENARFVVSEVYCRIHQKIDILSKRLNMSQDDGEKW--IVNLIRDTRMDAKIDLEKNVIPVYQSVIEKTRGLTFRTQVLGAAM Botci1 DL-LPKLITHLDRHLIFPLLQF-PEITKAKFELL--KKTNMTDYVASLHCEIYANKRQEILEIFGQESEKITDLLGREDVSDKVANLEFLKKVTIEMVNVLYDFGNFQYSCGNYGAAAELLY-QFRVLSAATWGKLACEIL-TGNWESAMEEVQKVKESIETKLHHRTWLIHWALFPFFNHEPARDICDLFPAFINTIQTACPWILRYLTAAVITNLKDIIRIVKQEDPVTDFIKALYLDFDFEEAQKKLEEVLRSDFFLENFVEAARHLISESYCKIHQRIDILSARLGLNQDDGEKW--IVNLIRDTRVDAKIDYKEGTVSVYQQVIERTKGGFFRTQVLSAAV Caeel DL-TQRMAPFLDLHLIIPLLEFIKSLTEMHRQLL--TKTNMIDSVIETYN--IEAKKKQIIDELKSKVDSVVAILEIPEVRERDGNLEHLTQFTVDMVDTLFKYSKFMYECGNYTVASVCLY-YYRNLVNALYGKLASEIL-LQEWEHARDDLLKLRAYIDANVTQRAWLMHWALFVYYNYPKGRDIIEMFQPYLNAIQVLAPHLLRYLAVAVVTSLKDLVKVIDIEDPVTDFLTCLYIKYDFDEAQEMLEEVLSNDFFLGDFRESARLLIFEMFCRIHQCITILARRLNMSQEEAERW--IVDLIRTYRIGAKIDSKLGQVSIHEQVMENTKRLTLRAQQIALQL Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow DL-STVLGQHLDRHLVLPLLDFLEEIARGKLDLI--SSTNMVDFAIDIYKTILVEKRESTVKVLHNSAEPVLNLFQNEEVQDKQHNLQYLQQFQPEMLDTLYEYAKFQFDCGNYTGAADYLY-HFNLLSSALWGKLACEIL-LHNWETALEEMTRLKEIIDSRLQQRTWLIHWSLFIFFHHPRGRDIVDLFTPYLNAIQTTCPHMLRYLATAVITNLKDLVRIIQQEDPITQLLECLYVNYDFDAAQLVLEKVVNNDFFLDDFIESARMLIFETYCRIHEVISILAEKLNMTADDAERW--IVNLIRNAKMDAKIDSQLSHVNIHQDIIEKTNILSFRAQLLSSAL Catan2 DL-TPTIAKYLDPQLVY-------EVLTQAFDLI-NDNSSRADFANELADAIIEARAKAANANPDDDVSRILDVM--ASANDRATNGAYIREVEAESIDKLFVVAKAHFEVGKFEEVVKLVD-QFRRISSAAWAKLASALL-SQDNKGALEAINRVRDSIEHALEQRLWLMHWALFVVFQVEGGLDAMDIFNPNMNAIETAAPWLLRYIVAASILTTRDIARYASQEDPLCQAYEALYWSVDLDAASAALAQVAHIDYFLAALLAGFRKQFLGVVSTVYSQMPKLVDMLHL------KWEQVVELL-----GENGELANGAVATRKNLFEKVDKLSHRSDNAIAEL Cioin DL-TSKVGCYLDRHLVFPLLEFLRDLHKGKLELL--SNTNMVDFAMDVHKTLLRDKRNNVVKSYTVKTEPIVHIFEQDEVRDGKQLFEYLEKFKLEDLDTLYDYAKFQYECGNYSGAAEYLYFHRVLVQDSLWGKLASEIL-MQDWDTAWEDLHRLQESIDSNLQQRTWLIHWSLFVFFNHAKGRDIIDLFPPYLNTIQTMCPWVLRYLTTAVITNLKDLVRVIQQEDPVTEFLECLYVHFDFDKAQEKLELVLSNDFFLDDFIENARLFIFETFCRIHQCISILADKLNMSVDEAERW--IVNLIRNARLDAKIDSKMGHVSSYEQVIEKTKSLGLRTQMLSTNV CocheC53 SL-LPKLMPNLDRHLIYPLLNFSVEQKKLLLELL--KPTNMTDFVGQLHQDVYKKKREEVLDQLEEATSKISGLLDDENVSDKQQNLAYLKEVDMEMVNQLLEFGQFQYSCGVYPHAAELLY-RFRVLTEATWGKLACEIL-SVNWDSAMEEINKLKEIIDTRLQHRTWLIHWSLFPLFNHETSRELTDMFPAYINTIQTNCPWILRYLAAAVITGLKDLIRIVRQEDPVTDFIKALYIDFDFEEAQKKLEEILKNDFFLDQFVDAARHLISESYCKIHQRIDILSTRLGLSQDEGEKW--IVNLIRDTRVDAKIDYQAGTVSVYQQVIERTKGGFFRTQVLSAAV Coere1 DL-TTRMIPSLDRQLVFPLLEFLEDVLKAKVELL--SSTGMVDYTGELYKQLFDKKREEVILESEMKTKHIREVIENPEVQDKLQNMKLLHECTPEMVLELYNYGQLQYSCGNYGGSADMLL-HFSILSSAMWGKLASEIL-LGNWEVAFEDILKLRETIDKTLQQRMWLLHWSMFVFFNHPKGRDIVDTFPQYISTIQNACPWILRYLVAAVVTNMQQLVKIIEQVDPVTEFIEALYIDFDFDRAAEKLEDVLDKDFFLDDFVENARFYFAEVYCRIHKRIDMLTGRLNMRQEEGEKW--IVKLIRDTRMDAKVDFKENTIPVYQQVIERTRALVFRSQVLNGAI Conco1 DL-TQKMIPYLDRHLAYPLLKFLADLQQAIYELF--SKTNMIDFTADLYKQIFAEQRTQVLEELQTEAQKVMSVIEKPEVQDKLQNIQYLKEFDPESINILYQYGKFQFDCGNYGTAADMLY-HFRVLSNAMWGKLASEIL-AGNFTAAYQDIMKLRELIDSTLQQRTWLLHWTLFVFFNYPKGKDLIDMFPQYINTIQTSCPWILRYVTAAVVTNIKDLVKAIQQEDPMTDFLLALYVEFDFDGAQSKLEELMSQDFFLEKFVENARIFILEAFCRIHQRINILSERLNMTQEEGEKW--IVNLMRDNRVDAKINFSDNTVSVTSQLIDKTKEISIHSQFMVNGL Conpu1 DL-SQTIIPYLDRHLAFPLLAHLEQVQAAQYELA--KGTNMVDYAVSLFEQLFSQKRDVAVERLQQEAQAVLDVIENPDVQDKNQNLQYLKDLTLEQITALYNFGKFQYTYGNYSGAADYLY-HFRVLSSAAWGKLAADIL-TGKWDTALEELTALRELVDARLHSRTWLVHWALFVYFNHPSGRTLLDTFPTYLNTIQTACPWVLRYLAAGAVLALKEVVRVIQTEDPVTDFLRELYVNFDFEAAQKALERVVGDDFFLDEFIDNARYLISEAYCRIHQRIDILSERLNLSRDEGEKW--IVNLIRETRMDARIDLEKNVIPVYQTVIEKTRGLAFRTQAMGAAL Copci DL-TKTIIPYLDRHLAFPLLAHLRDVQIAQYELV--KGTNMYDYSAQLFKSIFEEARKNALERLQQEAQAVFDVIENPEVQDKIQNLQYLKDLTLEQITALYHYGKFRYSSGNYSSAADYLY-HFRVLSSAHWGKLASDIL-SGRFDVALEELNTLRETIDTRLHSRTWLVHWSLFVYFNHPEGRTLLETFPTYLNTIQTASPWILRYLAAAAILSIREVVKVIQTEDPITNFLRELYVEFDFERAQQELEEVVSNDFFLEEFLDNARYLISEAYCRIHQKIDILSARLNLSPEDGEKW--IVNLIRETRMDAKIDLGKNVIPVYQTVIEKTRGLALRTQAMGAAL Croqu1 DL-TLRLVPHLDRHLVLPLLEFLDQLLQAKYDAL--RETNMITYLSGLHRELFIQKENEVMDELKASVEKVMDVISAPEVQDKAQNLSYLERVTLSQLAVLYQYGHYQYTIGNYGGSSDYLY-HYRVLSSSLWGKLASDIL-EGSFDSALEELNRLKEQLDQRLQQRTWWLHWSLFVYFNLEKGRDLVDTWQGYLNTIQTSCPYLLRYLVVALIVSVKEVIRAVTQEDPITEFIRLLYSEVDFEGARLALHKVFNDDFFLGPWLENCRTMISEAYCRIHHRIDILVNRLDMEGEEGEKW--IVRLVRDARLDAKIDFKENTVSVHQTVIERTKRLTAMSQEQAYKL CryneH991 DL-TQKLIPHLDRHLAIPLLNHLEQLARAQYDLA--KGTNMVNYVEQFHAQIAR-LRDEATQELQEKAQPVTKVIEDPDAGDKDRNLDLLRSIDIDQINALYHFGQYQYSLGDYGSAGNLLY-HFLILSSAQWGKLASNIL-NGEWDAALVQVRDLRETIDNPLQARTWLLHWSLFVFFNLNQGCQLLDMFPAYLNTIQTSCPHLLRYLVAAAIISVKELTRIVETEDPITSFLKDVFADFDLTQAQQRLESVVRSDFFLDEFVENARWLISEVICRLHRRIDILSKTLNLSNEEGEKW--IVNLIRDSRMEAKIDLKENMLTPTATLIETTRGLAFRSQAIQFAM Crypa2 DL-LPKLVTKLDRHLIFPLLEFSRELLKAKYELL--KKTNMTDYVANLYCDLFADKRQKVIENFEDSTNKLTELLQTEEVSDKVANLEFLKKVTIEMVNALYDFGNFQYSCGNYGAAADLLF-QFRLLSAATWGKLASEIL-STSWEAALDELKKVREGIDERLQHRTWLIHWALFPLFNNDAARDLLEMFPEYINTIQTSCPWILRYLTAAVITGLKDIVRIVRQEDPLTDFVRALFIDFDFEEAQRQLEEVIRGDFFLDVFVDNARHLIFESYCKIHARIDILSASLGLNNEDGEKW--IVNLIRDTRLDAKIDSKEGTVSVYQQVIERTKGGFFRTQVLNSAV Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 DL-TDKFVHFLDRHLVYPLIENLKEVEEWEYELL--KDTYMTKFVEDKWLGLFADKQQKIQVSLNDSTKKTLEILSSQEVQDKSYNREYLSKIDDAKIYELYKFGKFQYNRGDYVMASDLLN-NFRLLSSATWGKLAAEII-SFFWNEAMNEFNKLREIIDSRLNKRTWLIHYSLFIFFNSDSSEDMIDLFSSYLSTIQASCPWILRYLIVALLQTLRDIVRAVDVEDPFTKLIESLFVTFEFDNLSDLISVLIETDFFIQKLVLNMQELIFNTVTKVYTGLTELCKMFNE----------VVQKFLEERKDQVSVAEDGSITVYQQVYEKTKAFNFKTNQILNTA Dicdi DL-TKQICSFLDAHMMLPLINYLNEINKAMADIL--SQTGCCDYAINAYESILQAKKQELVNKLKEQCSFVTQYIESKKQQQKEKDIPFSQLITPEILDSIYRFSKLLFEIGQYGSAREHLE-IFLQLSSALWGILESDIL-SLNWGQAVGDISPLQDQIDSNLGQRAWLIHRALFVYFYNPESRSLVDLLDKYLNAIQTTCPHILRYLAVAIIVNLNALVRVVEQEDPITQFISSLFVKFNFEDAQAQLEKVLKNDFFLDEFMENARVCVFETYCNILESIDILCKNLRIDPESSEKW--IVEAIRNTRFSAKIDSANNQINSYRQVMDKTKALFNRGIEMVVGI Dmel DL-TRINCQFLDRHLTFPLLEFLQELLEYILETV--NKTNMIDYTMDTRKRLLVQRKAEVLKQLQNEVAPIMDILKNGESKDSKTFVNALQKFKVEHLESAYKLAKYLYECGNYQESTSYLYFCLIVMSNVLWGKLAAEIL-TLNWNTALEDLTRLRDYIDNALQQRTWLIHWSVLVFFNHPKGRDIIEMFPLYLNAIQTMCPHIMRYLATAVVINLKDLIKVIQQEDPITEFLECLYVNFDFEGARLKLQTVILNDFFINEFVEDARLMIFETFCRIHQCITILADKLNMKPNEAECW--IVNLIRNARLNAKIDSKLGHVSPYQQLVEKIDSLSMRSEHLAGLI Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba DL-TQVLCQFLDPHLALRLIEFAKDILQAKFDIV--KKTTIPDLISQVFSELLEEKRDLL-EEYQESCGEIMPILQDGELQDGTFTLAFLIS----------------------------------------------------------------KEFLNEYVKQRAWLLHWSLFVFFNADEASDLIDLFEVFRQALQLHAPHLLRYLAVVVVIFLLNLMSMFNQEDPILELISCVYRKFDFDSARGKIKAVFENDYFLDQFFEAARLFIFETYSQIHKRIDNLAEYLHLDMEAAERW--IVNMIRNASLDAKIDSTNNVVNPNAQVIEITRGQEIKNQGLLQRI Fomme1 DL-TKTIIPYLDRHLAFPLLAHLDEVHAAQYELA--KGTNMVDYSIALFEQLFASKRENALERLEQDAQAVLDVIENPDVQDKMQNLQYLKDLTLEQINALYHFGQFQYSYGNYSGAADYLY-HFRVLSSALWGKLASDIL-TGKWDIALEQLNELRELIDSRLQARTWLLHWSLFVYFNHSQGRTLLETFPAYLNTIQTSCPWILRYLATAAVLSLKEIVKIVQTEDPITNFLKELYLEFDFEAAQRELVQVVENDFFLDEFLDNARYLISEAYCRIHHKIDILSERLNLSREEGEKW--IVNLIRETRMDAKIDLEKNVIPVYQSVIEKTRGLAFRTQAIGAAL Fusgr1 SI-MPRLAPNLSRHLLFPLIQFEKELLSGKIKLL--EDTNMTDYVATLYCELYNKKRQEVLENYEQATAKIADLLTQDEVSDKVANLEFLKNVTMEMVNALYDFGQFQFRCGQYGPAADMLY-QFRVLSAATWGKLASEIL-QTNWESAVDELKNVRENIDSKLDHRTMLLHWSLFPLFNWEGAREILEMFAPFINTIQTSCPWILRYLIAAVITGIKDIIRYVRQEDPITQFVNALYIAHDFEAAREALAEVCRSDFFLDAFVDAARHLICESYCKIFSRMNILSAKLGLNPDDGEKW--IVNLIRETRLDAKIDSQDGTVNVYQQVIEKTKGGFFRTQVLNAAV Galma1 DL-SKTIIPYLDRHLSFPLLAHLEQVQLAQYELA--KGTNMFDYAVSLFEQIFDQKRKNAVERLQLEAQAVLDVIENPDVQDKNQNLQYLKDLTLEQITALYNFGQFQYSYGNYSGAADYLY-HFRVLSSAHWGKLASDIL-TGRWDVALEELNTLRDAIDSRLHSRTWLAHWSLFVYFNHEHGRTLLETFPTYLNTIQTSSPWILRYLAAAAILSIKEVVKVIQTEDPVTGFLKELYVEFDFEAAQRELEEVVGNDFFLDEFLDNARYLISEAYCRIHQKIDILSERLNLSPEEGEKW--IVNLIRETRMDAKIDLEKNMIPVYQTVIEKTRQLAVRTQALGVAI Ganpr1 DL-TPRLIPNLDPHMVLPLLEFLDQLLEAKYDLL--QDTKMIDFANDVHKQLFESRRQNVLEDLRDSTREVMEILSNPDVNDKLQNQRFLEEFRVSMLDRLYDYARFQYACGNYSGAAEMLY-HFRILSSALWGKLAAEIL-TQNWETALEDLVRLREMVDGRLQQRTWLLHWSLFVFFNHPKGRDIIDMFPQYINTIQTTSPHILRYLATAVVTNLKDLVRVVKEEDPVTEFVEALYVRYDFQAAQEKLEEVLFNDFFLDDFVETARLFIFETYARIHGRIDLISLLLGLEKESGEKW--MVNLIRNARLDGKVDAETNTVSVYQQIIERTKALSFRSSVLLNAL Gloin1 DL-TPKLIPYLDRHLVFPLLEFLIDLLKAKYELL--AKTNMVDFISMLYKTIFSTKRDEVLENLQSEAQKVLDIIENPEVQDKLQNLNFLKELTDKMLNTLYQFGQFQYNCGNYGGASDMLY-HFRVLSSALWGKLASDIL-DSNWDGALEEVQKLKETIDQKLQQRTWFIHWSIFVFFNHPKGRDIIDVFPSYINTIQTACPWILRYLTTAVVTNLKDLVKIIQQEDPITEFIESLYVKFDFEGAQHKLEKVLSNDFFLPEFVENARYLISETYCRIHLKIDILSQTLNLDQEAGEKW--IVNLIRDTRVDAKIDFKENTVSIYQQVIERTRGLSFRSQILSSTI Hisca1 DL-LPKLMPYLDRHLVFPLLEFADELTKAKYELL--KQTNMTDYVANLWQEIFVKKREEVVQQYVEDSSKITELLQDDNVNDKAANLKFLEEVTMDMVNILYDYGRFQYSCGSYANAAELLY-QFRVLSFATWGKLASEIL-TTNWEAAMEEVQKVKESIDTRLQHRTWLIHWSLFPFFNHDPARDLTDLFPAYINTIQTACPWILRYLAAAVITSLKDLIRVVRQEDPIVDFIKALYIDFDFEGAQQKLEEILRNDFFLDAFVDAARHLISESYCKIHQRIDI----------------------------------------------------------NAAV Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 DL-SKTVIPYLDRHLSFPLLAHLQDVQTAQYELA--KGTNMFDYAVQLFTQIFDVKRKNAVERLQQEAQAVLDVIENPDVQDKNQNLQYLKDLTLEQITALYNFGQFQYSYGNYSGAADYLY-HFRVLSSAHWGKLASDIL-TGKWDIALEELNTLRDVIDSRLHSRTWLVHWSLFVYFNHPQGRTLLETFPTYLNTIQTSSPWILRYLAAAAILSIREVVKVIQTEDPVTSFLKELYIEFDFEAAQRELEEVVANDFFLEEFLDNARYLISEAYCRIHQKIDILSERLNLSRDEGEKW--IVNLIRETRMDAKIDLEKNVIPIYQTVIEKTRGLALRTQALGAAV Lenti61 DL-TKTVIPYCDRHLVFPLLAHLEQVQTAQYELA--KETNMVDYAVSLFEQLFADKREKAVERLQQEAQAVLDVIENPEVQDKNQNLQFLRDVTLEQITALYNFGKFQYSYGNYSGAADYLY-HFRVLSSAHWGKLACDIL-TGKWDVALEELNTLRDAIDARLHSRTWLLHWSLFVYFNHPQGRTLLETFPTYLNTIQTSCPWVLRYLATAAVLSIREIVKVIQMEDPVTQFLKELYVEFDFEAAQKELETVVANDFFLEDFMDNARYLISEAYCRIHQRIDILSERLNLSRDEGEKW--IVNLIRETRMDAKIDLEKNVIPIYQSVIEKTRGLAFRTQALGAAM Malgl1 DL-TQTLLAYMDPHLGLPLLSHLKDLAKAQYELG--KKTNMVDYTMQFFREAVAERANQLENHLAKEAEHVLTVIEDPNVQDKAQNLEWLKQLTTDQINVLYEYGRFLFSCGKYSEASSYLY-HFCILSSVLWGKLACDTL-TGDWDRAMDDVRVLREYID--LQKRVWLLHWSLFVFFNHPNGRFLVEMFPTYLSTIQMSCWWLLRYLVIALVVTLREVSKDIQMEDPFIDFFRQLYVELDFECAQAELESVVRHDFFLDPFIEHARLLVSEVYCRIHQKVDILSKRLNMSKEDGEKW--IVKLICDTKMDAKIDLKEGVV------------------------ Mellp23 -----RLIPQLDRHLVLPLLEFLDQVLKAKYDAL--KETNMITYLSGLHREIFIQKEDEVMDELKASVEKVMDVISAPDVQDKAQNLSYLEKVTLSQIAVLYQYGQYQYTIGNYAGASDYLY-HFRVLSSSLWGKLASDIL-EGAFEAALEELNRLKEQLDQRLQQRTWWLHWSLFVYFNLEKGRDLVDTWQGYLNTIQTSCPYLLRYLVVALIVSVKEVIRAVTQEDPITEFIRLLYSEVDFEGARSALEKVFSDDFFLIPWRENCRTMISEAYCRIHHRIDILVYRLGMDAEEGEKW--IVRLVRDARLDAKIDFKENTVSVHQTVIER------------YVF Mnele DL-TNALSEFMDLHLVFPLLEFLESLMKSKYQLL--QNTNMVDFTIDVFHGLLHEKRSDVVTELQEKSSQVIEMFQRKDVRDSQQLWDYLSEFDRERLDDVFHYGKFMYDVGNYAIASTNLDFYRNLAPSAQWGKLASEIL-QQNWDEAMEELERLKDNISAALVQRAWLIHWGLFVYFNHPQGRDIIDVFKPYLNAVQTMCPHILRYITTAVVISIKELIKVLQQEDPITEFVESLYVNFNFDEAQAKLKTVIENDFFIDEFTENARLIISEIFCRIHQRIEILADNLNMEPAEAEKW--VVNMIRLAHLDAKIDSKNGYVPVYQKLIDKTKDLHLKANSCCQKI Monbr DL-TQAICQNLDPHLILPLLDHCADLKRAKMQVL--SRTRLIEQALELADATLDARMRSISKTWEKQLEPVFEMFENDEVATKNKDLSEL-EFTENTADLLYHGSKFYFDRGQYDLAHGLLY-NYRAVSTALWGKLAAAIL-SGNWQTAQEDMYLLLEYIDGGLQQRNWLLHWSLFVFFNQPDGPDIVDLFETCTNAMQTIAPHLFRYATAVAIMSMWEFVGIARQDDPVVGFLVSLIKDFDFVTAEEKLREVLSKDYFLDEFINTAQLYLFEVYLRVHSRVSIAATRLGKSEDDAEEW--LVKLIRDAKLDAQIDPASGEITVYQHVLDRTKNLQYRTYVIVESL Morel2 DL-TSKMIPFLDLHLVFPLLEFLTTLLEARYELS--LKTSMIDLIDKLHGELLVERRKEVLMNSQTEAQKVMDVIENPEVQDKLQNLQFLKDMTTEMIQTLYKFGQFQYSCGNYGGAADMLY-HYRVLSSALWGKLASEIL-SGNWDVAFEAIQELKEIIDKTLEQRTWFLHWSLFVFFNHSKGRDVVDFFPAYINTIQTSCPWILRYLTAAVVTNLKELVKVIEHEDPITEFVEALYVNFDFDLAKQKLEEVLENDFFLEEFIQNARCFISETYCRIHQKIDVLSQTLNMTKEEGEKW--IVNLIRDTKVDAKIDYKENTVSVYQQIIERTKGLSFRSQVLATSI Mucci2 ------MIPFLDRHLVFPLIEFLEELLQAKYDLF--KGSNMVDFVLDLYKKLFTDKRESVLEDLRTKAQKVMDVLEKPEVQDKAQNLQYLKEFTDDSINILYEFGQFQYNCGDYGGAADYLY-HFRVLSSATWGKMAAEIL-TGNWDAALEEMQKLREAIDSKLQQRTWLLHWSLFVFFNHPKGRDIVDMFPQYINTIQTSCPWILRYLATAVVTNMKELVKIIEQEDPVTEFVEALFVRFDFEGAQKKLEDVLSNDFFLEDFMESARQFISETYCRIHQKIDIMSQRLNLSQEEGEKW--IVNLIRDTRVDAKIDFEENTVSVYQQVIERTKGLSFRSQVLATAI Mydma DL-TSRVGAYLDRHLVFPLLEFLTELLKGRLELL--QGTNMLDFVKDEYQRLLLEKRQEVIKELEAATESITTAFEDPDFRDGTVLFKYLNDITTDNLATLYQYAKFQYECGNYAGASQYLYFYRVLVHSAVWGKLACEIL-TQNWDAALEDINRLKEIIDGDLQQRTWLIHWSLFVFFNHAKGRDLIDMFSSYLNAIQTTCPHILRYLTTAVITNLKDLVKVIQQEDPITEFLECLLVNFDFDGAQKKLETVLLNDFFLDDFIENARLFIFETFCRIHQCISILADKLNMSPEAAERW--IVNLIRNARLDAKIDSKQGHVAVHQQVIERTKGIMYRTQTVAQSI Neucr2 DL-VLKLAPHLDRHMIFPLLEFNREILAAKYALL--KKTNMTDYVANLYCELYAERRQKVFEKYEQETAKITELLQRDDVSDKVANLEFLKKVTIDMVNALYDFGQLQYSCGNYADASELLY-RFRVLSYATWGRLACEIL-TMNWESAMEELQKVRESIDTRLQHRTELVHWALFPLFNYDKARELLDLFAGFINTIQANSPWILRYLTVAVITNMKDVVRIVKQEDPITRFVHALCIDFDFEEAQQQLEEVLRSDFFLDDFVDSARHLIFESYCKIHARISLLSARLGLNNDDAEKW--IVNLIRDTRLDAKIDYKEGTVSVYQQVIERTKGGFFRTQVLTAAV Orpsp11 ----------MDRHMIFPLLEFLEELVQAHYDLL--AETHMVDYANEIYCEIYEERRNQVLEELRDESSEIMNIIQDPNVQDKIQNIQFLKAFKPEMLQNLYDFAKFQYNCGNYSGAAEMLY-HFRILSQALWGKLASEIL-TTNWETALEDLNKLREAIDQKLQQRTWLIHWSLFVFFNHPNGRNIIDMFPQYFNTIQISCPWILRYLTAAVITSIDDLVKVIQQEDPITEFIECLYVKFDFNGAKEKLEDVLFNDFFLEDFIEAGRLIIFETYCKIHQNIDIMSEMLNLEKDSGEKW--IANLIRSARLDAKIDIKS--------------------------- Pench1 DL-LPRLIPYLDRHLVFPLLEFS-EITRAKYELL--KHTNMTDYVANLWQEIFVKKREEVLQHYQDQSEKITELLQDEEVSDKAANLRFLEEVTNEMVNSLHDYGRFQYSCGSYGNAAELLY-QFRVLSAATWGKLASEIL-TTNWEGAMEEVQKVKDSIETRLTNRSWLIHWSLFPFFNHDPARDLTDLFPAYINTIQTSCPWVLRYLAAAVITNLKDLIRVVRQEDPVTDFVKALYVDFDFEEAQKKLEDVLRSDFFLDAFVDAARHLISESYCKIHQRIDILSARLGLNQDEGEKW--IVNLIRDTRVDAKIDYKEGTVSVYQQVIEKTKGAFFRTQVLSSAV Phybl2 DL-TLRMIPFLDRHLVFPLIEFLEDLLKAKYDLF--NNSNMVDFVLDLYKKIFVDKREVVLEELQGEVQEVMTILEKPEVSDKAQNLNYLKELTENRINILYEFGQFQFSCGDYGGAADMLY-HFRVLSSASWGKLAAEIL-TGNWEAALEEMQNMREAIDQKLQQRSWLIHWSLFVFFNHPKGRDIVDMFPQYINTIQTSCPWILRYLATAVVTNMKELVRIIEQEDPVTEFIEALFIHFDFEGAQKKLEDVLSNDFFLEDFMESARQFISETYCRIHQKINIMSQTLNLNQEEGEKW--IVNLIRDTRVDAKIDFEENTVSIYQQVIERTKGLSFRSQVLASAV Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 DL-SKTIIPYLDRHLAFPLLAHLEEVQAAQYELA--KGTNMVDYAVSLFQELFSGKRENAVERLQLEAQAVLDVIENPDVQDKSQNLQYLKDLTLEQITALYNFGQFQYTYGNYSGAADYLY-HFRVLSSAHWGKLASDIL-TGKWDVALEELNTLRDIVDSRLHSRTWLVHWSLFVYFNHPEGRTLLETFPTYLNTIQTACPWILRYLATAAILAIKEIVKVIQTEDPVTSFLKELYVEFDFEAAQRELERVVGADFFLEEFLDNARYLISEAYCRIHQRIDILSERLNLSKDEGEKW--IVNLIRETRMDAKIDLEKNVIPIYQSVIEKTRGLAFRTQALGAAM Polpo DL-TKKICSFLDAHLMLQLVDFLEDINRAKADIL--AQTGCCDYAITVYQSILQEKKQKLVAQLKEACQVVTQYIEAKKEQQTVAALTFGSLVTPEIVESLYRYAKLLFETGQYKNAREYLD-IYVKLSSASWGILEADIL-SSNWAGAVADIPQIKEEIDSNLHQRAWLIHRSLFVYFNQPDSRALVDLLDKYLNAIQTICPHVLRYLAVAIITNLYQLVKVIEQEDPITIFVSSLYVRFNFEESQQYLEQVLKQDFFLDDFMEHARACIFETYCNIHENIDILCKNLGIAPENSEKW--IVEAIRNARFVAKIDSANNQINAYRQVMDKTKGLFNRGIEILVGI Pucgr2 DL-TSRLIPQLDRHLVLPLLEFLQQLLQAKYDAL--KETNMITYLTGLHRELFSQKEEQVMDTLQESVDQIMSVISAPEVQDKAQNLAYLEKVSLSQIAVLYQYGHYNYTIGNYGGSSDYLY-HFRVLSSSLWGKLASDIL-EGSFDAALEELNRLKEQLDQRLQQRTWWLHWSLFVYFNHDKGRSLVDAWQGYLNTIQTSCPYLLRYLVVALVVSIKEVLRAVSQEDPITDFLLNLYVKVDFEGAQKALEKVFNVDFFLNPWVENCRIMISETYCRVHHRIDILASRLGLQQEEGEKW--IVNLVRDARLDAKIDFKENTVSVYQTVIERAKRITAISQDQTYKL Punst1 DL-TKTIVPYLDRHLAFPLLAHLEQVQTAQYELA--KGTNMVDYAVQLFEQLFTEKRENAVERLATEAQAVLDVIENPDVQDKMQNLQYLKDLTLEQIAALYHFGQFQFTYGNYSGAADYLY-HFRILSSAHWGKLASDIL-SGKWDVALEELNNLRDAVDARLHSRTWLLHWSLFVYFNHPQGRTLLETFPTYLNTIQTSCPWILRYLTTAAVLAIRDIVKVIVTEDPITDFLKELYVQFDFEAAQQQLETVVENDFFLEDFLENARYLISEAYCRIHQKIDILSQRLNLAPEEGEKW--IVNLIRETRMDAKIDLEKNVIPVYQTVIEKTRGLAFRAQAMGAAL Rhior3 DL-TMKMIPFLDRHLVYPLLEFLEDLLQAKYNLF--QNSHMVDFVLSLYKKLFSEKREKVLEELRTKAQKVMQVLEKPEVQDKAENLQYLRDFTDDSIDILYEFGQFQYNCGDYGGAADYLY-HYRVLSSATWGKMAAEIL-TGNWDGALEEMQKLREAIDQKLQQRTWLLHWSLFVFFNHPKGRDIVDMFPQYINTIQTSCPWILRYLATAVVTNMKELVKVIEQEDPVTEFVEALFVRFDFEGAQKKLEGVLMNDFFLEDFMESARQYISETYCRIHQKIDIMSQRLNLSQEEGEKW--IVNLIRDTRVDAKIDFEENTVSVYQQVIERTKTLSFRSQVLATTI Rhoto1 QL-LPNVLPHLDRHLVLPLLDFLEETLKAKIDLLGDGKTNMVTFVEGLKRELLRKREQKVLNELRAQAQGVMEVISNPEVQDKQHNLTYLKEVTLDQIALLYKFGQFQYSIGHYGGASDYLY-HFRVLSSAMWGKLASDIL-EGSWDAALEELNGLREHIDQRLQQRTWWLHWSLFVYYNHPNGRELLESWQNYLNTIQTAAPWLLRYLVAAVVISVRDVVRALSQEDPVTEFLRKLYGEVDFEGAREEMADELADDFFLDEFVENARYLVSEAYCKIHHRIDILSDRLGLSREEGERW--IVDLVRDARLDAKIDLKQNIVPVYQTVIEKSRGLLFRSQALASAI Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro DL-TRQLCGFLDNHMTLALIQNAEQLITSKLKVL--ESAHFFDAMKEVYHDVVLEKEEAFNDSLSEELSKVYDVFSKQEVPDPAKLTEKLKEFEPKMLDTMFKAARAYYDLEQYATAGTMLY-NYRPLTSALWGRLAVEIM-SEKFEEATEVLGVLQSNIKETLQQRAWLMHWSLFIFFFGDNGESLLEKFNEFIGAIQTMCPHLLRYFAVVAVITIRDIVRMIRHKDPITQLLECIYIDFDFDKALELLEKVLDLDFFLTDFVESASKLIFEVYCKIHSSISIVAERLSKTASEAEKW--IVDLIQSADLSARIEQAEGYVSTYDQVLDSTRSIPLRTRALLDNF Schco3 DL-SKTIIPYLDRHLAFPLLAHLEQVQLAQYELA--KGTNMFDYAASLFELSFNEKREKAVERLQLEAQAVLDVIEKPEVQDKNQNLQYLKELTLDQISALYNFGNFQFSYGNYSGAADYLY-HFRVLSSAHWGKLASDIL-TGQWETALEELNTLRDTIDSRLHSRTWHLHWSLFVYFNHPQGRTLLETFPAYLNTIQTSCPWILRYLTTAAILSLRELPKIITTEDPITRFLKDLYVDFDFDKARDELEKVVQNDFFLDEFVECARGLISEAYCRIYGRIDILSERLNLSPDEGEKW--IVNLIRETRMDAKIDLEKNQIPVYQTVIEKTRGLGLRMQAMGIGL Schpo1 DL-SQKIMQHLDRHLIFPLLEFLKELLQAKYDLL--KDTNMTDYVANLWTNLFAEKRRSVLSELEEEVQGILGVLENPDLQDKGQNLQHLQEITPERIAVLYKFAQFQYNCGNYGGASDLLY-HFRAFSSATWGKFASEIL-TVDWDGAMEELGKLREMVDSKLRNRTWLLHWSLFPLFNH-NGCDLCDLFTPYLNTIQTSCPWLLRYLTVAVVTNMRDLVRIISQEDPVTSFISALYTEVDFEKAQHCLEEVLKTDFFLDHFLEGARKLLAEAYCRIHSVISVLANKLEMDSAQ------LIQLVENRNNDESIESTSTNVSAFQQIIDRTKSLSFESQNLEQSL Sorma DL-VLKLAPHLDRHMIFPLLEFNREILAAKYALL--KKTNMTDYVANLYCELYAERRQKVFEKYEQETAKITELLQRDDVSDKVANLEFLKKVTLDMVNALYDFGQLQYSCGNYADASELLY-RFRVLSYATWGRLACEIL-SMSWESAMEELQKVREGIDTRLQHRTQLVHWALFPLFNYDKARELLDLFAGFINTIQANSPWILRYLTVAVITNMKDIVRIVKQEDPVTRFVHALCIDFDFEEAQHQLEEVLRSDFFLDDFVDSARHLIFESYCKIHARISLLSARLGLNNDDAEKW--IVNLIRDTRLDAKIDYKEGTVSVYQQVIERTKGGFFRTQVLTAAV Sphar DL-TSTIAEYLDRHMVFPLLKFLEEILTVKLDLL--EKTCMVDYAADIYKGLFSERREQVLAELQQSTAPLTQALEQDWVQDKRFNQEYLTNVDMACLDKLYEFAKFQFDIGNYSVTAEYLT-NFRVLSGALWGKFASEIL-MHNWDTAMEDLNRLKESLDENLQQRTWLLHWSLFVFFNHEKGRDIIEMFPQYINTIQTTCPHILRYLTAAVICNVKELVKAIQRGDPITEFLECLYVNFDFEGAQQKLEAVLENDFFLDEFIENARMFIFETYCRIHQVISILGEKLNMTTDEAEVW--IVNLIRNARLDAKIDSKMGTVSVYHQVIEATKGLSFRSSAMIETI Spipu1 DL-TTKIGHYLDRHMVAPLLEFLKDLMQAKYDLL--SKTKMIDYTNQIYKEIYEERRAGVLEELTEQSSEIMDMIQDPIVQDKLANIQFLSDFKPEMLNALYEFALYNYDIGNYSSAAEMLY-HFRILSSSLWGKLAAEIL-TQNWETAYDDLNRLKEMIEQRLQQRSWLIHWSLFVFFNHPKGRDIADLFPQYLNTIQTACPWILRYLTTAVVVNLKDLIKVVQQEDPITEFIECLYVNFDFDGAQQKLDEVIANDFFLEDFKENGRLFIFETYCRIHQCIDIVSQKLDLSPEAGEKW--IVNLIRNARMDAKIDSKTNTVSIYQQVIERTRALSFRSSLLASNI Sporo1 QL-LPRMVENLDRHLVLPLLDFLDEILKAKIDLL--AKTNMVTFVEGMQRELFRKREQEVVNDLRAQAEGIMDTISKPEVQDKQHNLTYLKEVTLDQIAYLYKFGQFQYSIGHYAGASDYLY-HFRVLSSAMWGKLAADIL-EGSWDAALEELGGLREFIDQRLQQRTWWLHWSLFVYYNHPNGRELLESWQNYLNTLQTSAPWLLRYLVAAVVISVRDVIRALGQEDAVTEFLRKLYGEVDFEGAREEMGGVLEDDFFLDEFVENARFLVSEAYCKIHHRIDILSDRLGMTREEGERW--IVDLVRDARLDAKIDLKQNIVPVYQSVIEKSRGLLFRSQAIASAI Stehi1 DL-TKTIIPYLDRHFAFPLLAHLEEVQAAQYELA--KGTNMVDYAVNLYEQLFATKRENAVERLQQEAQAVLDVIENPDVQDKNQNLQYLKDLTLEQITALYNFGQFQYTYGNYSGAADYLY-HFRVLSSAHWGKLASDIL-TGKWDVALEELNTLRESIDSRLHSRTWLTHWSLFVYFNHPQGRTLLETFPAYLNTIQSAAPWILRYLSVAAVLSIKEVVKIVQMEDPITRFLKELYVEFDFEAAQRELEQVVGNDFFLEEFLDNARYLISEAYCRIHQRIDILSERLNLSKDEGEKW--IVNLIRETRMDAKIDLEKNVIPIYQTVIEKTRGLSIRTQALGAAM Tapde11 NI---ELLQYLDRHLIYPILDFALEMLQAKFDLL--QGTNMPGHCAELYKQIFADKQGVIEAELETQSQKVLEVLENPEVQDKAQNLVFLQDITIDQINVLYKLGQFDYNRGNYAGAIDHLY-HFRVLSGATWGKLASEIL-TANWDDAESELTKLKEQVDADLKNRAWLLHWALFPLLKSTNKAILQELFPAYLNAMQTSAPHLLRYLTVAVLSTLKDLVRVLEVEDPITDFARAILVKYDFVKAATMYHLAISADYFLDEIMQSLRLAVAEAYLRLHRTAEIMAAIIDTTKED------LVQLVTRD--DGTIE-------TLQDLVNKTKALAQRSAHTQSQI Thetr HL-TTVMAPYLDKHLVLVLLDFLQELDEVRLEII--AKTNMVDYAVSVHEALLVASREKVVKALKEAAGPLLEVLGDEEAENGRYSREGMLEVSAETIDALNDYAKCLYECGKYEAAASYLA-HYIKLAAAMWGKLASEILAAADWEAAYDDLLALKDVIDPPLQQRTWLIHWSLFVFFNHPEGRNIIDFLDAYLNTIQTSCPHILRYLTTAVVTNLKTLVTVIQQEDPITEFVCSLYVDFDFDLARAKLEDVLRSDFFLDDFLANARLFIFETYCRIHQNIDLLADKLDMDRDQAEKW--IVNLVRNANIDAKIDSAADQVSIYSQIIEKTKGLSLRSSVLSNNC Treme1 DL-TQKLIPHLDRHLAIPLLNHLEKLAKAQYDLV--KGTNMVDYVSQLYDLVARALRSQATQDLQERVQPVMKVIEDPDALDKEKNLELLSNISLDQINQLYHFGQYQYSVGQYSDAASFLY-HFLIFSSAHWGKLACNIL-GGEFEAAASEVKDLRDIIDNPLQARTWLLHWSLFVFFNLGTGCQLLDMFPAYLNTIQTSCPHLLRYLVAAAIISVRELTKIVQMEDPVTRFLKDLFTDFDFAKAQDRLENVVRADFFLDDFVENARWLVSEVFCRVHQRIDILSRTLNMSNEEGERW--IVNLIRDSRIEAKIDLKSNMLTPTAYLIETTRGLTFRSQAINMAM Trire2 SI-LHKVAPYLSRHLLFPLIQFEKKILSGKIKLL--DDTNMTDYVASLYCELYTKKRQDVLDKYEKATEQIANLLTQDEVSDKVANLEFLKNVTIEMVNALYDFGQFQFRCGQYGPAADMLY-QFRVLSAATWGKLASEIL-STNWESAVDELKNVREGIDTRLDHRTMLIHWSLFPLFNFEGAREILDMFASYINTIQTSCPWILRYLIAAVITGLKDIVRYVRQEDPITQFVNALYIAHDFNAAREALEEVCRSDFFLDAFVNAARHLICESYCKIFSRMNILSAKLGLNPDDGEKW--IVNLIRETRLDAKIDSQDGTVNVYQQVIEKTKGGFFRTQVLNAAV Umbra1 DL-TMRMIPFLDRHLVFPLLDFLEDLLKAKHELL--SNTNMVDFVLKLYQEIFAEKKEKVLEEFQTQTQNIIEVIENPEVQDKLQNLHFLKEFTDSMVLTLYDYGQLQFNCGNYGGAADMLY-HFRVLSSALWGKLAAEIL-TGNWDVALEEMQKLREAIDQKLQQRTWLIHWSLFVFFNHPKGRDIVDMLSQYINTIQTSCPWILRYLTTAVVTNIKELVKIIQQEDPITEFIEALYVHFDFEGAQQKLEEVLSNDFFLEDFMENARQFISETYCRIHQKIDVLSQTLNLTQEEGEKW--IVNLIRDTRVDAKIDFEENTVSVYQQVIERTKGLSFKSQVFASAI Ustma22 DL-TQTLLPYLDRHLGLPLLSHLTDIAKAQYELA--KNTSMVDYALQLYEQAIEKQRENAIDKLGSEVDHVLEVIQDPSVQDKAQNLQWLEELTSEQINALYRYGYFQFSCGNYGDASSYLY-HFRVLSSSHWGKLASDIL-VGEWEQALSELKLLREQLDSSLKKRAWLLHWALFIFFNHPGGRELVEMFPVYLNTIQTTCWWLLRYVVAALLLSIKDIVNIIDSEDPIVDFLSKLFVDFDFEAAQEQLEQVASKDFFLDELVEACRVVISEAYCRIHSKVDILVKRLNLSKEDGEKW--IVNLVRDTRADAKIDFKEGMVPVYQTIIEKTRGFTFRTSAMGTAI Walse1 DL-TTRLIPFLDRHLALPLLNYLNQLQSAQYELV--KGTNMVDYA-------QDDKKKHIVQQYQQKAKEVLEVLTNPDVQDKHKNREILQELQPNSIEVLYDYGHFQFSSGNYVEAAEYLY-HFRILSSSQWGILASNIL-KGSFDQALEDFNGLRETIDRQLQQRTWLLHWGLFIFFNHEQGRDLVDLLTAYLNTLQTACPWLLRYYTIAVIATIRDLIRVVNIEDPLTKFVEALYTDFDFNVVEAQLDTVFTQDFFLDDFFSSARFYVVEAYCRIHSHVTIIAQKVGLSEDAFKSW--ISK-------EEKFVVDSNAVNVLSTILDKSSALALRSQSIKQAI Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2460.fasta_al_trimmed; alignment length = 75] Allma1 KQPGIAIGRLCEKCDGKCVICDSYVRPATLVRLCDECNYGKCCICGAYYCKECEKDRDGCPKIVNIGSSKTDLFY Ashgo11 KLPGTSIGRLCERCDGKCPSCDSNVRPLSKVRICDQCSFGKCILCGAYYCWECEKDRDGCPRILNVGSNKTDRHF Aspfu1 --------------------------------------------------------------------------- Aurde31 RQPGIAIGRLCEKCDGKCPVCDSYVRPDTLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Batde5 KQPGIAIGRLCEKHDGVCIICDSLVRPADLVRICDECNYGRCVVCGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Botbo1 RQTGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Botci1 KQSGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICEECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDLFY Caeel KQPGIAIGRLCEKCDGRCVICDSHVRPCTLVRICEECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSAKTDLFY Canalb1 KQPGKSIGLLCSNCDGKCPICDSFVKPTEQVRICQDCSQGKCILCAAYYCLECEKHREGCPRIINVGGTKTDMIY Cangl NPAGINTGILCEKCDGRCPSCDSYVRPRSRVTVCDQCSFGQCILCGAYYCWECGKNRKGCPRIINIGSNKMDRYF Capow KQPGIAIGRLCDKCDGKCVICDSYVRPCTLVRVCDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGVSKTDMYY Catan2 KQPGIAIGRVCEKCDGKCVVCDSHVRPATIVRICDECNYGKCLVCGAYYCKECEKDRDGCPKIVNIGSAKTDLFY Cioin --------------------------------------------------------------------------- CocheC53 KQSGISIGRLCDKCDGKCPVCDSYVRPTTLARICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDLFY Coere1 QLPGIAIGRLCDKCDGKCVICDSLVRPEKAVHICDECNFGNCIICNAYYCRECEKDRDGCPKIINIGTARTDLFY Conco1 --------------------------------------------------------------------------- Conpu1 --------------------------------------------------------------------------- Copci RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Croqu1 KQAGIAIGRMCEKCDGKCPICDSYVRPQTLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY CryneH991 RQPGIAIGRMCEKCDGKCPVCDSYVRPMTLVRICDECSFGKCIVCSAYYCTECEKDRDGCPRIINMGASRVDAFY Crypa2 KQSGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDLFY Debha1 KQPGTHMGMLCQLCDGKCPICDSFVKPTTKVRICDECSFGKCILCGAYYCLECEKDREGCPRIVNVGSSKADMIQ Dekbr2 KQPGIHIGKVCAKCEGKCPTCESVVHPYRVVHVCDDCAYGRCIICGAYYCYECEKDRDGCPRIINVGSTRTDYYF Dicdi KQTGIAIGRVCDKCDGKCVICDSYVRPTTLVRICDECNYGKCVICGAYYCFACEKDRDGCPKIVNLGGSKIDLFY Dmel KQPGVAIGRLCEKDDGKCVICDSYVRPCTLVRICDECNYGRCVICGAYYCKSCEKDRDGCPKIVNLGSSKTDLFY Enthi KQPGIAVGKLCAKDEGKCPICDSYVRPYKKVRICDDCNFGKCIICGAYYCRNCEKDRDGCPKIINIGSSRADLFY Falba KQPGVAIGRLCDKCDGKCVVCDSLVHPATLVRICDDCNFGRCVICGAYYCKECEKDRDGCPKIVNVGTARMDLFY Fomme1 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Fusgr1 KQAGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDIGR Galma1 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Ganpr1 KQPGIAIGRLCEKDDGKCVICDSYVKPHILVRICDECNYGRCVICGAYYCKECEKDRDGCPKIINLGSSKTDLFY Gloin1 KQPGIAIGRLCEKCDGKCVICDSYVRPDTLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Hisca1 KQTGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCIVCGAFYCFECEKDRDGCPKIINLGSSRTDLFF Klula1 KLPGTSVGKVCDRCDGRCPLCDSDVRLISKVRICDSCSSGRCIICGALYCWDCERSRDGCPRILNVGSNKTDRLY Lacbi2 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Lenti61 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Malgl1 ----------------------------------------------AYYCAECEKDRDGCPKAINLGHTRMDAMF Mellp23 KQSGIAIGRMCEKCDGKCPICDSYVRPQTLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Mnele KQPGVAIGRLCEKCDGRCVICDSYVRPCSLVRICDECNYGRCTICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Monbr KQPGVAIGRLCEKCDGKCVVCDSYVRPSTLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGAARTDLFY Morel2 KQPGIAIGRVCEKCDGKCVICDSYVRPVTLVRICDECNYGRCVVCGAYYCANCEKDRDGCPKIVNLGSSKTDLFY Mucci2 KQPGIAIGRLCQTCDGRCIICDSYVRPATLVRICDECNFGRCVICGAFYCVECEKDREGCPKIINLGSSKTDLFY Mydma KQPGVAIGRLCEKDDGKCVICDSYVRPCTLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Neucr2 KQSGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDLFY Orpsp11 ------IGRVCEKCDGKCVICDSFVRPCTIVHICDECNYGRCVVCGAYYCK------------------------ Pench1 KQPGISIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDLFY Phybl2 KQPGIAIGRLCEKCDGKCVICDSYVRPATLVRICDECNFGRCVICGAYYCVGCEKDREGCPKIINLGSSKTDLFY Picst3 KQPGKSIGLVCLACEGRCPLCDSYVKPTTKVRICHECSMGKCILCAAYYCLECEKDREGCPRIVNVGSLKSDMMI Plicr1 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Polpo KQPGIAIGRVCDKCDGKCVVCDSYVKPTTLVRVCDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Pucgr2 KQPGIAIARMCEKCDGKCPICDSYVRPQTLVRICDECNFGRCIICGAYYCTECEKDRDGCPKIVNLGASRTDLFY Punst1 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Rhior3 KQPGIAIGRLCEKDDGKCVICDSYVRPATLVHICDECNFGRCVICGAYYCVGCEKDREGCPKIINLGSSKTDLFY Rhoto1 KQPGIAIGRTCEKCDGKCPICDSYVRPAEIVRICDECNFGRCIVCGAYYCAECEKSRDGCPKIVNIGTSRTDAFY Rozal11 KQPGIAIGKLCEHCDGRCPVCDTHVRPATLVRVCDECNYGRCVICGAYYCKECEKD------------------- Sacce1 KQPGVQTGLLCEKCDGKCPICDSYVRPKRKVRVCENCSFGNCIICNAFYCWECGKDKDGCPRILNLGSNRLDRHF Salro KQPGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNIGASKTDLFY Schco3 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Schpo1 RQPGITVGKLCERCDEKCPICDSHVRPTTLVRICDECAFGRCIICGCYYCSECEYDRDGCPRVINLGSSRTDWFY Sorma KQSGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCFECEKDRDGCPKIINLGSSRTDVSF Sphar DILGVAIGRLCEKDDGKCVVCDSYVRPATLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Spipu1 KQPGIAIGRLCEKCDGKCVICDSYVRPADLVRICDECNYGRCVICGAYYCKECEKDRDGCPKIVNLGSSKTDLFY Sporo1 KQPGIAIGRTCEKCDGKCPICDSYVRPAELVRICDECNFGRCIVCGAYYCAECEKSRDGCVKIINIGASRTDAFY Stehi1 RQPGIAIGRLCEKCDGKCPVCDSYVRPETLVRICDECNFGRCIICGAYYCAECEKDRDGCPKIVNLGASRTDLFY Tapde11 --------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------- Treme1 RQPGIAIGRLCDKCDGKCPVCDSYVRPMTLVRICDECSFGKCIICGAYYCTECEKDRDGCPRIINMGASRVDAFY Trire2 KQPGIAIGRLCDKCDGKCPVCDSYVRPTTLVRICDECSFGKCVVCGAFYCYECEKDRDGCPKIINLGSSRTDLFY Umbra1 KQPGIAIGRLCEKCDGKCVICDSYVRPATLVRICDECNFGRCVICGAYYCVGCEKDREGCPKIINLGSSKTDLFY Ustma22 KLPGIAIGRLCEKDDGKCPICDSYVRPSTLVRICEECNFGKCIICGAYYCAECEKDRDGCPKVVNLGASRTDLAY Walse1 RQPGISIGRLCDKCDGKCPVCDSYVRPQTIVKICDECAFGKCVICGAYYCAECEKDRDGCVKIVNLGSSKLDLAY Zygro1 RQPGTHVGLLCEKCDGRCPICDSYVRPKSKVRICGQCAFGSCIICGAYYCWECEKNRDGCPRITNVGSNRTDRHF [Cluster2466.fasta_al_trimmed; alignment length = 318] Allma1 IIPS-FTLECGETL-TSVPVAYKTWGTLNDNAIVVCHALSGSADVADWWGPLLRVFDPRRWFIVCCNVLGSPYGSASPVTTGELYGAHFPRVSVRDDVRLH-RLVLDQLGVESVAFAIGGSMGGMQVLEWYVRHLVPMATAARHSAWCIAWGEAQRQAIFADPAYNAGEYAGLAAARIQAMLTYRTRDSFQARFARRQSYLRYQGDKFVHRFDANCYVAITRKLDTHDLARPYALQRLVLAVASDGL--FTVAEHEELVAALPNGELGVIASPDGHDGFLLEFDQ--VGHAVDEF-M--RRVAPEESSTFGEVDLTAW Ashgo11 EVPE-LTLESGITI-SKFPVAYKTWGKLNDNVLVICHALTGSADVADWWGPLLLAFDTSRFLVVCLNALGSPYGSFSPLTTGARYGPEFPLCTVRDDVRAH-KLVLESLGVRQIACVVGGSMGGMVVLEWYVQNVVALATSARNSAWCISWSEAQRQSIYSDPKYLDGYYVGLSAARMSALLTYRSRDSFETKFARKQSYLRYQGNKFVKRFDANCYISITRKLDTHDLGRDRVLNDMVIGINSDGL--FTYSEQEFLATHMPNARLERIDSPDGHDAFLLEFKL--INDLIIGF-F--KENLREKDSVFGEAEITNW Aspfu1 IIPS-FTLESGVTL-YNVPVAYTTRGEMSDNVLVICHALSGSADVADWWGPLLQAFDTSRFFVICLNSLGSPYGSASAVTKGL-YGPEFPLTTVRDDVRIH-KMILDDLGVRQIAAVVGGSMGGMLTLEYYVRAIVPIATSARHSAWCISWGEAQRQSIYSDPKYEDGYYTGLGAARMSALLTYRSRNSFESRFGRNQSYLRYQGEKFVKRFDANCYIAITRKLDTHDVSRYRALSQIVLGIESDGL--FTFEEQKEIAAGIPNSRLKRIESPEGHDAFLLQFEQ--VNRYILEF-F--REVLPDKSSTFGEADITAW Aurde31 TVPS-FELECGQTL-TDVPVAYKTWGTLNDNVMVICHAFTGSADVEDWWGPLIRAFDPRRFFIFCANVLGSPYGTASPVTTGQPYGPDFPPTTIRDDVRLH-KLVLDRLGVESVAVVIGGSMGGMATLEWYVRHIIPLATSARHSAWCISWGEAQRQSIFSDPEYRDGWYSGLAAARMAALLTYRSRDSFESRFGRKQSYLRYQGEKFNSRFDANCYVHITRKLDTHDVARGRVLGQIVISIQTDGL--FTPSEQRELAKHIPSAELVVIDSPDGHDGFLLEFEQ--INRHILAF-L--RKNFPEKTSMFGEADVTMW Batde5 VLDS-FKLESGIVL-EQVPVAYKTWGTLNTNVMVLCHAMSGSADVEDWWGQLLAPFDTSKFFIFCGNVLGSPYGTASPCTTGLKYGPTFPLTTIRDDVRLH-KSILDLLGVQQVKFCIGGSMGGMQALEWYVRHIVPIATSGRHSAWCISWGETQRQAIYSDSNYCDGYYVGLAAARMVALLTYRARNSFQARFGRKQSYMRYQGDKF-----------VSRQLDNHDISTGRVLASIVIGIETDVL--FTVEDQHELAAGIPNSQVVIVPSEEGHDGFLLELDH--MRTLLQDF-I--QKCAPE------NANTNQP Botbo1 VIPE-FELESGVVL-KQVPVAYKTWGRLNDNVMVICHAFTGSSDVVDWWGPLMKVFDPTRYLVFCGNVIGSPYGTVSPVTTNRPYGPEFPPTTIRDDVRLH-KLILDSLSVTSVAVAIGGSMGGMTVLEWYVRNIVPLATSARHSAWCISWGEAQRQSIYSDPAYQDGYYQGLAAARMSAMLTYRSRDSFESRFGRKQSYLRYQGEKFTQRFDANCYIHITRKLDTHDLARGRALSSLVISVETDGL--FTPGEQREITSYVPHGKLVTIASADGHDGFLLEFEQ--INRCVLAH-L--QERLPEKTSTFGEADVTRW Botci1 --------------------------------MVICHALTGSADVSDWWGPLLRAFDISRFFVICMNSLGSPYGSASPVTNER-YGPEFPLTTIRDDVNIH-KLLLDDLGVRQVAAVIGGSMGGMLVLEWYVRAIVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYAGLGAARMSALLTYRSRNSFEARFGRNQSYLRYQGEKFVKRFDGNCYIAITRKLDTHDVSRYRALSQIVLGIESDGL--FTFDEQKEIAASVPNARLRKIESPEGHDAFLLQFEQ--VNQHILEF-L--NEVLPDKSSTFGEADITAW Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 EIPE-YTLECGETL-HNFPVAYKTWGKLNDNALVICHALSGSSDVDDWWGELLRAFDPSRYLIICINFLGSPYGSCSPVTTGKPYGPSFPLVTFKDDVGIQ-RLILDSLNVKRLAAVVGGSMGGMLALEYYVQKVVALATAARTSAWCISWNETQRQCIFSDPFYDDGYYSGLSAARMAALLTYRSRNSFESRFGRKQSYMRYNGSKFINRFDANCYIAISRKLDTNDLSRGRVLKDLVIGIESDHL--FTITEQKLLADNIPNAIFETLDSEEGHDAFLLEFEK--INSFITSF-L--NN----------------- Cangl EVPE-LVLESGVVL-NNFPIAYKTWGHLNDNCMVICHALTGSSDVSDWWGPMLLGFDPSRFFIVCLNSMGSPYGSFSPLTTGRPYGPEFPLCTVRDDVRAH-KIVLESLGVKSVACVIGGSMGGMLALEWYVHNLVALATSARHSAWCISWSEAQRQSIYSDPKYMDGYYTGLSAARMSALLTYRSRNSFENKFSRRQSYLRYQGAKFVNRFDANCYIAITRKLDTHDLARDRVLESIIIGIKSDGL--FTYSEQEFLAEYLPNSRLEKIESPEGHDAFLLEFKL--INQLILEF-L--NKNVKDAGSVFGEAEVTNW Capow VFDE-FTLECGRVL-RNVEVGFRTWGTLNDNAIVVCHALTGHSDVSSWWAPILKPLDTSVYFVICANVLGSPYGTASPLTTQQPYGAAFPHVTIRDTVRLHRRLVQEALGVQRIFAVVGASLGGMQALEWVVAHLVLIACCGRQSAWCIGWSETQRQAIINDPKWRNGNYQGLATARMIAMLTYRSSSSMEERFGRQQSYLRYQGRKLVQRYDANCYMRLMQMMDTHDVARGRALAQLVVGVESDLL--YTIAEQAEMSSHIAHAEFVAIPAYDGHDGFLVEFAR--LNEVLNGF-L--KRHEPR------------- Catan2 LHPSAFPLECGATLPAPVPVAYKTFGTLDSNVIAIFHAVSGSADVSDWWAPLLHSFDTRRFFIVCCNVLGSPYGSASPLTTGKQWGPDFPVASVRDDVRLF-KHVYDHLGIKRIQFAIGGSMGGMHALEMYVRFVVPIASVSRLGAWGISWGEAQRQCIFADPNYQNGHYAGLASARMQAMLTYRSHHSFEARFGRKQSYLRYQGDKFVARFDANCYIALTRKMDTHDVARGRVRAAVVLGVESDGL--FAIGEQRALAECLEDAELQVIDSPDGHDGFLLEFEQ--VGRHIGKF-M--RERAPEFSSTFGEADLVAW Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 IIPE-FTLESGVVL-HNVNVAYKTYGTLADNAMVICHALTGSADVGDWWGPLLKAFDISRFFVVCMNSLGSPYGSASPVTLGP-YGPEFPLTTVRDDVNIF-KLLLDDLGVKQIAAVIGGSMGGMLVLEFYVKTIVAIATSARYSAWGISWGEAQRQSIYSDPKYDDGYYTGLGAARMSALLTYRSRDSFESRFGRNQSYLRYQGEKFIKRFDANCYIAITRKLDTHDVSRYRALSLIVLGIQSDGL--FTFAEQQELAAYIPNASLKTIDSPDGHDAFLLEFEQ--VNNHLLGF-L--NAELPEKTSTFGEADITAW Coere1 IIPS-FTLESGEVL-TSVPVAYKTWGQLNTNCMVICHALTGSTDVVDWWGPLLRAFDTDHFFVVCCNILGSPYGTASPVTTGTFYGPDFPLTTIRDDVRIH-RQVLDALGVKQVAICIGGSLGGMQCLEWYVKVVVPIATCGKHSAWGISWGEAQRQAIYSDPNYCDGRYHGLSAARMTALLTYRSRNSFESRFGRKQSYLRYQGEKFTKRFDANCYIAITRKMDMHDVGNSHALKQMVVGIESDGL--FTINEQYELAEHIPHAQLATIDSADGHDGFLLEFAQ--LNRLIRSF-V--RDTLPEKSSVFGEADVMKW Conco1 IIPS-YTLESGHTL-TQIPISYKTWGTLNDNVMVICHALTGSADVEDWWGPLLKAFDTENFFIFCANVLGSPYGSASPLTSGKPYWNEFPDTSIRDDVRLH-RLVLEDLGAKQVAICIGGSLGGMQVLEWFVKNVVPIATSGKHSAWGISWGEAQRQSIYSDPNYCGGKYSGLAAARMSALLTYRSRNSFESRFGR-QSYLRYQGDKF-------------------------------------------------------------------------------------------------------------- Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Copci TVPS-FQLECGAVL-KEVPVAYKTWGKMNDNVMIICHAFTGSADVEDWWGPLMKAFDPNRFFIFCANVLGSPYGSASPVTTGKPYGPKFPPTSIRDDVRLH-KLVLDHLGVSSVAVVIGGSMGGMAVLEWYIRHVIPLATSARHSAWCISWGEAQRQSIYSDPGYEGGFYSGLAAARMSALLTYRSRDSFESRFGRKQSYLRYQGEKFIKRFDANCYIHITRKLDTHDVARGRVLAQLVISIATDGL--FTPLEQREIAEAIPDAKLVTIESPDGHDGFLLEFEA--INRHVLEF-L--KREFPEKTSLFGEADITRW Croqu1 LVSQ-LELESGLIL-EDVPVAFRTWGKLNTNCMVICHALTGSADVEDWWGPLMLVFDPTRYYIFSANVLGSPYGTASPVTTGNRWGPEFPSTCPRDDVRLQ-KIILDHLGVRSIAVVIGGSMGGMACLEWYVRNIVPIATCPRHSAWGISWGEAQRQSIYSDPKYLDGYYTGLAAARMAALLTYRSRDSFETRFGRRQSYLRYQGEKFVNRFDANCYIHLTRKMDAHDVDYGRGLAGVVVAIDSDGL--FMLGEQREMVQEMPGAKLVVVESRDGHDGFLLEFEQ--INQHVLGH-L--HERLSEKESAFGEIVVTDW CryneH991 IIPS-FTLESGVTL-NNVPVAYKTWGKLNDNCLVICHALTGSADVEDWWGPLLKAFDPTRFFIFCGNVIGSPYGTISSVTTGKPFGPEMPGSSVKDDVRLH-YIILKSLGVRSVAAVVGGSMGGMTVLEYFVRAIIPLATSARHSAWCISWGEAQRQSIYSDPDYKDGYYRGLAAARMAALLTYRSRDSFESRFGRRQSYLRYQGDKFTGRFDANCYIHITRKLDTHDLSAPSALSLEVIGIESDGL--FTTSEQRELAAGIPDAELVVIPSPDGHDGFLLEFEA--INGWVEGW-L--KRKMPEKESVFGEADVTRW Crypa2 VIPS-FTLESGVTL-QNVPVAYTTKGKLSNNAMVICHALTGSADVGDWWGPLLRAFDVSRFFVVCMNSLGSPYGTASPVTNER-YGPEFPLTTIRDDVRLH-RLLLEDLGVKQVAAVVGGSMGGMLVLEWYVRSIVPIATSSRHSAWCISWGEAQRQSIYADPKYNDGYYTGLGAARMSALLTYRSRNSFESRFGRNQSYLRYQGGKFVKRFDSNCYIAITRKLDTHDVSRDRALALIVLGIESDGL--FTFAEQQELAEHIRNARLGKIESPEGHDAFLLQFEQ--VNKYILEF-L--HEVLPDKSSTFGEADITAW Debha1 EIPS-YTLECGEVL-NNFPVAYKTWGRLNDNVFIICHALTGSSDVQDWWGPLLKTFDPSRFFIICINFLGSPYGSCSPVSTGKPYGPLFPLVTVKDDISIQ-KLILDSLGVEGIACVIGGSMGGMIALEYYVKSVISLATSARASAWCISWNETQRQCIFSDPNYDDGYYSGLSAARMAALLTYRSRNSFETRFGRNQSYLRYQGNKFVNRFDANCYISITRKLDTHDITRNRFLSNLVIGIQSDGL--FTYGEQQLLGQCIPNCVLKKINSPEGHDAFLLEFEI--IDKYCKEF-L--HSKLPEGNSVFGEANITNW Dekbr2 EIPR-FELECGEVI-TKVPVAYKTWGKLNSNCMIITHALTGSADVSDWWGPLLKAFDPSKFFIICLNSLGSPYGSASPVTYGGRYGPEFPSCTIRDDVRIH-KSVLDSLGVKKVPICIGGSMGGMLALEWYVENVVALATSAKHSAWCISWGEAQRQCIYSDPKYNDGYYNGLGAARMAALLTYRSRNSFESRFGRQQSYLRYQANKFVGRFDANCYISITRKLDTHDVGRDRALESRVIGISSDAL--FTLSEQIFIAKHLQNSTIHKINSNEGHDAFLLEFKE--INGLISGF-E--NKHLKNKESVFGEADVASW Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 IAPA-FTLESGVTL-RDVPVAYKTWGRLNDNVLVICHAFTGSSDVEDWWGPLMKAFDPKRYFIFCGNVMGSPYGSASPVTTGEPYGPEFPATTIRDDVRLH-KLVLDHLGVASVAVVIGGSMGGMAVLEWFVRHIIPIATSARHSAWCISWGEAQRQSIYSDPAYDDGYYSGLAAARMAALLTYRTRDSFESRFGRKQSYLRYQGDKFTARFDANCYIHITRKMDTHDIARGRILSTLVIGVQSDGL--FMVSEQREIFEHIPDAELVIIQSPDGHDGFLLEFQQ--INTHILRF-L--KREFPSKTSVFGEADITRW Fusgr1 IVPE-FTLESGVTL-YNLPVAYTTRGKLNNNAMVICHALTGSADVSDWWGPLLRAFDTSRFFIVCMNSLGSPYGTASPVTKGR-YGPEFPLTTIRDDVNLH-KLILDDLGVKQLAAVVGGSLGGMFVLEWYIRCVVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYTGLGAARMSALLTYRSRNSFESRFGRNQSYLRYQGRKFVTRFDSNCYIAMTRKLDTHDVSRNRALAMIVLGIESDGL--FTFAEQEEIAQHVPNARLERIESPEGHDAFLLQFEQ--VNNYVLSF-F--KEVLPDKSSTFGEADITAW Galma1 VIPS-VTLECGSTI-KEVPVAYKTWGNLNDNAMVICHAFTGSADVEDWWGPLMKAFDSNRFFIVCCNTLGSPYGSASPVSTGRPYGPEFPPTTIRDDVRIH-KLVLDHLEVRSVAVVIGGSMGGMAVLEWFVRRIIPLATSARHSAWCISWGEAQRQSIYSDPSYQDGYYSGLAAARMSALLTYRSRDSFESRFGRKQSYLRYQGDKFTARFDANCYIHITRKLDTHDIARGRVLSTLVISIATDGL--FTTSEQREIAEHIPQAELVVIPSPDGHDGFLLEFEQ--INTHILKY-L--KREFPEKTSVFGEADITSW Ganpr1 ILPS-VTLESGATI-TDVPVAYNTWGTLNTNCVVVCHALSGSSDVSDWWGPLFQVLDTDRFFVIGFNVFGSPYGSASPLTCWPAYGPDFPSTTVRDDVRAH-ERILRELGVTRVQCVIGGSMGGFAALEWFVRTVIPVATSSRHSAWCVSWSEVQRQAIFADPVYDDGYYAGLTAARMCALMTYRARVSTESRFSRRQTYLRHHGRKFLSRFDPNCYVHITRKMDTHDVARGRVLGTVVIAVSSDFL--YPVEEQEELARGIPNSRLRVVDSLHGHDGFLIELKQ--VNKHIQEF-L--KEFIPENGDISGGLKMTAK Gloin1 IIPE-FTLCSGHTL-YKVPVAYKTWGALNDNVMVICHALSGSSDVQDWWGPLIRAFDPTKFFIFCGNVLGSPYGTASPVTTGKYYGPEFPLTTPQDDVRLH-KLILDSLGINQVAICIGGSMGGMQILEWYVKTLVPIATSARNSAWCISWNEAQRQSIYSDIKYRDGYYSGLSAARMSALLTYRSRDSFESRFGRKQSYLRYQGDKFVNRFDANCYINLTRKMDSHDIGKDRVLNSIVIGIESDGL--FTISEQYKLAEFIPNSEMVTIQSPDGHDGFLLEFDQ--INRHLVRF-I--NKFLPEKESLFGEA--VKW Hisca1 IVPS-FTLESGVTL-LNVPVAFTTRGTLSDNALVVCHALSGSADVSDWWGPLLQAFDVTRFFVICLNSLGSPYGSASAVTRGL-YGPEFPLTTIRDDVRIH-KLVLDDLGVRQIAAVVGGSMGGMLVLEYYVRSIVPIATSSRHSAWGISWGEAQRQSIYSDPKYEDGYYSGLGAARMSALLTYRSRDSFESRFGRNQSYLRYQGEKFVKRFDSNCYIAITRKLDTHDISRHRALSQIVIGIESDGL--FTFAEQQELADGIPDSRLRNIDSPEGHDAFLLQFEQ--VNRHILEF-F--REVLPDKNSTFGEADITAW Klula1 EVPE-LELECGITI-NNFPIAYKTWGYLNDNVLVICHALTGSSDVSDWWGPLLLAFDPSKFFIICLNSMGSPYGSFSPLSTGERYGPEFPLCTVRDDVNAH-RIVLDSLGISSIACVIGGSMGGMVALEWYVKNLIALATSARHSAWCISWSEAQRQSIYSDPKYLDGYYVGLSAARMSALLTYRSRNSFENKFARSQSYLRYQGEKFIKRFDANCYISITRKLDTHDLARDRVLGSFVIGISSDGL--FTYSEQEFLANNIPKARLEKIDSPEGHDAFLLEFKL--INELIKSF-L--ATNCKGTNSVFGEAEVTNW Lacbi2 TIPS-FKLECGTTL-REVPVAYKTWGKLNDNVMIICHAFTGSADVEDWWGPLMKAFDPNRFFIFCANVLGSPYGSASPITTGRLYGPEFPPTTIRDDVRIH-KLVLDHLSVTSVAVVIGGSMGGMAVLEWYIRHVIPLATSARHSAWCISWGEAQRQSIYSDPGYHDGFYSGLAAARMSALLTYRSRDSFESRFGRKQSYLRYQGDKFTARFDANCYIHITRKMDTHDLARGRVLSTIIIGIATDGL--FTTTEQRELADAIPNAELVVIYSPDGHDGFLLEFEA--INTHILRF-L--KREYPGKTSLFGEADITRW Lenti61 YVPS-FTLESGHVL-KDVPVAYKTWGTLNDNVMIICHAFTGSSDVEDWWGPLMKAFDPSRYFIFCANTMGSPYGSASPVTTGKRHGPEFPLTTIRDDVRIH-KLVLDHLGVSSVAVVIGGSMGGMAVLEWYIRRIIPIATSARHSAWCISWGEAQRQSIYSDPSYQDGYYSGLAAARMAALLTYRSRDSFERRFGRKQSYLRYQGDKFTSRFDANCYIHITRKLDTHDVARGRVLGTEVIGIQSDGL--FMPSEQRVIAEGIPDAKLVMIPSPEGHDGFLLEFEL--INKHILEY-L--KAEFPEKTSMFGEADITRW Malgl1 ---------------------------------------------------------------------------------------------------------------------MGGSMGGATSLEWYVRSIVVLAASPRHSAWCIAWCEIQRQAIEADTRFNGGRYGGLAAARMCALMTYRQPHSFERRFSRMQSYLHHHGTKFLTRFDALCYIHLSNKLDSHDVTRDRVLGHLILSVTSDML--YTPAEQASIHEAIPTSELVHIESAEGHDGFLIEYPQ--IDRAIRAF-M--------HASSL-------- Mellp23 VLSE-FQLVSGLIL-KEVPVAYQTWGKLNSNCMIICHALTGSADVEDWWGPLMLAFDPTRYFIFCANVLGSPYGTASPVTSGMRWGPEFPSTSPRDDVRLQ-KLILDHLGVQSIAVVIGGSMGGMQCLEWYVRNIVPIATCARHSAWGISWGEAQRQSIYSDPKYQDGYYTGLAAARMAALLTYRSRDSFETRFGRRQSYLRYQGTKFVNRFDANCYIHLTRKMDSHDVDFGRGLEQIVVAIDSDGL--FMLSEQREMVKAMPNARLVVVESQDGHDGFLLEFEQ--INRHVLSH-L--HERLSEKESLFGEIPITDW Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr IFDS-FKLENGQVL-EQVHVDYSTYGTLNDNVLVVCHALTGNANLHTWWGGLLRAFDTDRYFIVCANILGSCYGTTGPASNHRPYRHRFPNVTVRDTVHLHARLLTEVLHVTAIPCVVGGSLGGMQTLEWLVQSFITIACGPDHSPWQIAFGEVQRQAIYADPCWQEGNYRGLAVARQMAMVSYRTPQAYEHKFARRQCLLAQQ----------------------------------LIAVV--------------------------------------------------------------------------- Morel2 IIPE-FTLDSGHVL-YQVPVAYRTWGTLNDNVMIICHALSGSADVEDWWGPLMRAFDPTKFFIICCNVLGSPYGTASPVTTNVSYGPEFPLATIRDDVRLH-KLILDDLGVKSVAICIGGSMGGMQVLEWYIKAIVPIATSAKHSAWCISWGEAQRQSIYSDPNYLDGYYVGLGAARMAALLTYRSRNSFESRFGRKQNYLRYQGDKFIHRFDANCYIAITRKMDVHDVAAGRVLDNIVIGVESDGL--FTISEQYELAEHLHNSEMVVVQSPDGHDGFLLEFEQ--INNAILSF-MSKHEHIRDKESLFGES-IVNW Mucci2 IIPE-YTLESGVTL-TNIPIAWKTWGKLNDNCMVICHALTGSADVEDWWGPLMRAFDYTKFFIVCCNVLGSPYGSASPLTTGDIYGPEFPLVSVRDDVALH-RLILDHLGVKQIAVCVGGSMGGMQVLEWYVRTIVPIATSGRHSAWGISWGEAQRQSIYSDPNYADGYYVGLSAARMSALLTYRSRNSFESRFGRKQSYLRYQGNKFINRFDANCYIALTRKMDSHDLSRGRILASIVIGIESDGL--FTISEQYELAEGMADTEMIVIDSPDGHDGFLLEFDQ--INRHLLNF-I--KRVVPEKTSLFGEADITQW Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 --------------------------------MVICHALTGSADVSDWWGPLLRAFDVSRFFIVCFNSLGSPYGTASPVTKGR-YGPEFPLTTIRDDVRLH-KLLLDDLGVRQVAAVIGGSLGGMFVLEWYVRCVVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYTGLGAARMSALLTYRSRNSFEARFGRNQSYLRYQGSKFVKRFDSNCYIAMTRKLDTHDVSRGRALALIVLGIESDGL--FTFAEQEELAQHIPDSRLERIDSPEGHDAFLLQFEQ--VNRYILNF-L--REVLPDKSSTFGEADITAW Orpsp11 IIPE-FELECGYVL-KNAPVAYKTLGKLNDNVIVLCHALSGSSDFEDWWGDLVKPFDTNIFFIFCGNVLGSPYGSASPVTTQRIYGPEFPLATIRDDVRIH-RAVLDRLNVKSVEYVIGGSLGGMQALEWYVHNLVAIATCASQSAWGISWDEAQRQAIFNDPNFNYGYYCGLSTARMQAMMTYRTRDSFQARFGRKQSYLRYQGDKFISRFDANCYVSITRKVDTHDISRDRALSLIVVGIASDGL--FTASEQEEIANNIPNAQLEWIESDDGHDAFLLEFKQ--MQDLLLKF-M--KERTPKKASLFGEF----- Pench1 VIPS-FKLESGVTL-YNVPVAYTTRGTLADNVLVICHALSGSADVADWWGPLLQAFDVSRFYVVCLNSLGSPYGSASAVTNGY-YGPEFPLTTVRDDVNIH-KLVLDDLGVKQIAAVVGGSMGGMLTLEYYVRAIVPIATSARHSAWCISWGEAQRQSIYSDPKYDDGYYTGLGAARMSALLTYRSRNSFESRFGRNQSYLRYQGDKFVKRFDANCYIAMTRKLDTHDVSRRRALGRVVLGIESDGL--FTFAEQQEIAAGIPNSRLERIDSPEGHDAFLLQFEQ--VNRHIVEF-F--HEVLPDKSSTFGEADITAW Phybl2 IIPS-FTLESGVTL-DQVPVAWKSWGKLNDNCMVICHALTGSADVEDWWGPLMRAFDPTRFFIVCCNVMGSPYGSASPLTNKENYGPEFPLASVRDDVRLH-RLVLDQLGVKQIAVCIGGSMGGMQVLEWYVKAMVPIATSGRHSAWGISWGEAQRQSIYSDPNYADGYYAGLAAARMSALLTYRSRNSFESRFGRKQSYLRYQGDKFINRFDANCYIALTRKMDSHDVSRGRVLESMVIGIESDGL--FTISEQYELADCIPKAEMIVIQSPDGHDGFLLEFDQ--INQHILKF-I--HSTLPEKTSLFGEADITQW Picst3 EIPS-YTLECGEVL-SRFPVAYKTWGRLNDNVILICHALTGSSDVQDWWGPLLKTFDPSRYFIICINFLGSPYGSASPVSTGKPYGPSFPLVTVKDDIGIQ-KLILDSLSVRSIACVIGGSMGGMLALEYYVRSIIALATSARASAWCISWNETQRQCIFSDPFYDDGYYSGLSAARMAALLTYRSRNSFETRFGRKQSYLRYQGNKFITRFDANCYISITRKLDTHDITRSRFLQSLIIGIQSDGL--FTYGEQQLLGENIPDSSLKKLDSPEGHDAFLLEFEL--INNYCLKF-L--QDKLPEGNSVFGEANITNW Plicr1 IVPS-FTLECGRTL-HQVPVAYKTWGRLNDNVMVICHAFTGSADVEDWWGPLMKAFDPNRFFIFCANVLGSPYGSASPITTGKPYGPEFPRTTIRDDVRIH-KLVLDQLNVSSVAVVIGGSMGGMAALEWYIRHVIPLATSARHSAWCISWGEAQRQSIYADPAYEDGYYSGLAAARMTALLTYRSRDSFESRFGRRQSYLRYQGDKFTARFDANCYIHITRKMDTHDVARGRVLSRLVFGIESDGL--FTTTEQRELASHIPDAELVIISSPDGHDGFLLEFEQ--INGHILRY-L--RREFPDKTSLFGEADITSW Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 IVSQ-FRLTSGVLL-TDVPLAYRTWGKLNTNCMVICHALTGSADVEDWWGPLVLVFDPTRYFIFCANALGSPYGSASPVSTGKKWGPEFPSTTMRDDVNLQ-KILLDHFAVRTVSVVIGGSMGGMTCLEWYVLNIVPIATCPRHSAWGISWGEAQRQSIYSDPKYCDGYYIGLAAARMAALLTYRSRDSFESRFGRKQS-------KHLVKYSPPNHICDIKGTSSSD-----SISPVITDVKEDPL--CSKSRSIRMACSLWSSS----------RNLLILFQT--PGWLLLKV-L----------------DTTGS Punst1 VVPA-FDFECGRTL-YEVPIAYKTWGKLNDNVMIICHAFTGSADVEDWWGPLMKAFDPSKYFIFCANVTGSPYGSASPVTTGKPYGPEFPLTSIRDDVRLH-KLVLDSLGVSSVAVAIGGSMGGMAVLEWYIKHIIPIATSARHSAWCISWGEAQRQSIYSDPGYDDGYYSGLAAARMAALLTYRSRDSFESRFGRKQSYLRYQGDKFVARFDANCYIAITRKMDTHDVARGRVLATLVIGIQTDGL--FTISEQREIAAHIPGAELVVIQSPDGHDGFLLEFEQ--INGHILRF-L--KREFPGKTSVFGEADITRW Rhior3 IIPQ-YTLESGVKL-TNVPIAWKSWGKLNNNCMIICHALTGSADVEDWWGPLMRAFDPTKFFVICCNVLGSPYGSASPLTTGNIYGPEFPLVSIRDDVQLH-RLILDDLGVKQVAICIGGSMGGMQVLEWYVRSIVPIATSGRHSAWGISWGEAQRQSIYSDPSYGEGYYVGLSAARMSALLTYRSRNSFESRFGRKQSYLRYQGTKFVNRFDANCYIALTRKMDSHDISRGKMLAAIVIGIESDGL--FTISEQYELAEGMADTEMVVIDSPDGHDGFLLEFDQ--INRHILNF-I--KRVLPEKNSLFGEADITQW Rhoto1 TVSE-FTLESGVTL-RNVSVGFKTWGKMNDNVMVICHALTGSSDVEDWWGPLLHAFDPTRYFIFCANVMGSPYGTASPVTDGGWWGPEFPSTTTRDDVRLH-KILLDHLGVSTVAVVIGGSMGGMAVLEWYVRNICPIATSARHSAWGISWGETQRQSIYSDPEYESGWYRGLSAARMAALLTYRSRDSFESRFGRKQSYLRYQGDKFVSRFDANCYIHLTRKMDAHDVGRNR-LSLVVIAISTDGL--FTLTEQRELASAMPDAKLVVVDSPDGHDGFLLEFEQ--INEAVLQF-L--HERLPEKASLFGEADITRW Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 QVPE-LVLESGVVI-NNFPIAYKTWGTLNDNVLVICHALTGSADVADWWGPLLLAFDPSRFFIICLNSMGSPYGSFSPLTTGVRYGPEFPLCTVRDDVRAH-RIVLDSLGVKSIACVIGGSMGGMLSLEWYVKNMVALATSARHSAWCISWSEAQRQSIYSDPNYLDGYYAGLSAARMSALLTYRTRNSFENKFSRRQSYLRYQGTKFINRFDANCYIAITRKLDTHDLARDRVLSTIIIGIQSDGL--FTYSEQEFLAEHIPKSQLEKIESPEGHDAFLLEFKL--INKLIVQF-L--KTNCKAKTSVFGEAEVTNW Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 IVPS-FTLECGRTL-REVPVAYKTWGKLNDNVMIICHAFTGSADVEDWWGPLMKAFDPNRFFIFCANTLGSPYGSASPVTTGRPYGPEFPATTIRDDVRIH-KLVLDHLGVRSVAVVVGGSMGGMAVLEWYVRHIIPLATSARHSAWCISWGEAQRQSIYSDPMYQDGFYSGLAAARMSALLTYRSRDSFESRFGRKQSYLRYQGDKFTARFDANCYIHITRKLDTHDIARGRVLSTLVISIATDGL--FTPSEQREIAASIPDAELVVIQSPDGHDGFLLEFEQ--INTHICKF-L--RREFPEKTSVFGEADVANW Schpo1 IVPK-FTLECGDIL-YDVPVAFKTWGTLNNNCLLLCHALSGSADAGDWWGPLLRAFDPSHFFIVCLNSLGSPYGSASPVTTHSVYGPEFPLATIRDDVNIH-KLILQRLGVKQIAMAVGGSMGGMLVLEWFVRSIVPISTSLRHSAWCISWSEAQRQSIYSDPKFNDGYYSGLGAARMSALLTYRSKCSFERRFARTQSYLRYQAKKFVSRFDANCYISITKKLDTHDITRGRVMKDLVLGIESDGL--FTFDEQVEIAKSFPNATLEKIISAEGHDGFLLEFTQ--VNSHIQKF-Q--KEHLIDRESVFGEMDITSC Sorma VIPS-FTLESGVTL-HNVPVAYTTRGTLNDNAMVICHALTGSADVSDWWGPLLRAFDVSRFFIVCFNSLGSPYGTASPVTKGR-YGPEFPLTTIRDDVRLH-KLLLDDLGVKQVAAVIGGSLGGMFVLEWYVRCVVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYTGLGAARMSALLTYRSRNSFEARFGRNQSYLRYQGSKFVKRFDSNCYIAMTRKLDTHDVSRGRALALIVLGIESDGL--FTFAEQEELAQHIPDCRLERIDSPEGHDAFLLQFEQ--VNRYILNF-L--REVLPDKSSTFGEADITAW Sphar HLPS-FELECGRSL-INCPLAYTTYGTLNENCVLVGHSLTSNTNVAEWWSCLIRLLDLDRYYVVCVNYLGSPYGSASPLTRTRAYGKHFPRVTMRDNVNAQKELLTKVLGVTHLAMAAGGSMGSMLALEMFVSELLLVAGCAQHPDWAIGLGDSQRFAIYSDATWQHGDYKGLYAARMAAMLTYRTPQSITARFARQESYLRYQGEKFVKRFDGACYAHLTMTLDSHDVGRQRIMKDLVVGIDSDNL--YPIELQREMALCMPNSLLHTVKSPHGHDSFLIEIEE--LNKVTCEW-R--------DGKYFGERDTRDW Spipu1 HLDS-FELESGITL-RDVPVAYKTWGKLNTNAMIICHALSGSADVEDWWGPLLRAFDTDVFFIFCGNVLGSPYGTASPVTTNQPYGPNFPIATIRDDVRLH-KQILDNLGVKQIQFAIGGSMGGMQVLEWYVRNIVPIATSGRHSAWCISWGEAQRQAIYSDPNYANGHYTGLAAARMQALLTYRSRNSFESRFGRKQSYLRYQGDKFVKRFDANCYISITRKMDTHDISRGRVLTRIVIGIESDGL--FTIGEQRELAEHIPNAELIVIISPEGHDGFLLEFEQ--MNKYISDF-I--RRNGQAKNSVFGEADAMMW Sporo1 VVSE-FQLESGVVL-KDVSVGFRTWGKLNDNVMVICHALTGSSDVEDWWGPLLRSFDPTRYFIFCANVMGSPYGTSSPVTDAKWWGPEFPKTMVRDDVRLH-KLLLDHLGVVTVAAVIGGSMGGMAVLEWYVRNICPIATSARHSAWGISWGEAQRQSIYSDPDYESGWYRGLAAARMAALLTYRSRDSFESRFGRKQSYLRYQGDKFVSRFDANCYIHLTRKMDSHDVGRDR-LSLIVIAISTDGL--FTLTEQRELAASMRDAELVVIDSPDGHDGFLLEFEQ--INNHVLRF-L--HARLPEKASLFGEADVTAW Stehi1 TVPS-FELECGHVL-KQVPVAYKTWGKLNDNAMIICHAFTGSADVEDWWGPLMKAFDPSRYFIFCANVLGSPYGTASPITTGELYGPEFPGTTIRDDVRLH-KHVLDHLGVKSVAVVVGGSMGGMAVLEWYIRHVVPIATSARHSAWCISWGEAQRQSIYSDPIYEDGYYSGLAAARMAALLTYRSRDSFESRFGRNQGYLRYQGDKFTARFDANCYIHITRKMDTHDLARGRVLARLVIGIQTDGL--FTTTEQIEIASGIPDAELIIIPSPDGHDGFLLEFER--INRHLMEF-L--RREFKEKTSMFGEADIAAW Tapde11 RFDR-VVLESGAVL-DNVPVGYKTWGHLNDNCLIICHAFTGSADAEDWWGPLFKAFDYSKYFIFCGNSLGSPYGSASACTTGAIYGPEFPLVTVRDDVQVH-KRIIDALDVKQIACVVGGSMGGMLVLEWFVKTLIPVATSARASAWNISWGETQRQSIYCDPKYEDGYYAGLGAARMSALLTYRSRNSFEMRFGRNQSYLRYQAQKFVKRFDANCYISITRKLDTHDISRGRALAMIVLGIESDGL--FTFSEQEEIASHMPNAKLDRIISPEGHDGFLLEFGQ--MNDKIIGF-Q--KKYLPEKPSTFGEVAITEW Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 IIPS-FTLESGVTL-QNLPVAYKTWGTLNDNCLVLCHALTGSADVEDWWGPLLRAFDPTRFFIFCGNVIGSPYGTISSVTTNRPYGPEMPGSSVKDDVRLH-YIILRRLGVESIAAVVGGSMGGMTTLEYFVKAIIPLATSARHSAWCISWGEAQRQSIYSDPEYKDGYYRGLAAARMAALLTYRSRDSFENRFGRRQSYLRYQGDKFTGRFDANCYIHITRKLDTHDLSHPSALSLLVIGIESDGL--FTTTEQKELAAHIPDAELVVIPSPDGHDGFLLEFEA--INGWIDGW-M--RRKMPTKESVFGEADVTRW Trire2 IVPE-FTLESGVTL-HNVPVAYTTRGKLSDNAMVICHALTGSADVSDWWGPLLRAFDTSRFFIVCMNSLGSPYGTASPVTNGR-YGPEFPLTTIRDDVNLH-KLILDDLGVKQVAAVIGGSLGGMFVLEWYVRCVVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYTGLGAARMSALLTYRSRNSFESRFGRNQSYLRYQGKKFVKRFDSNCYIAMTRKLDTHDVSRDRALALIVLGIESDGL--FTFAEQEEIAKHVKNARLERIDSSEGHDAFLLQFEQ--VNRYVLEF-L--KEILPDKSSTFGEADITAW Umbra1 IIDQ-FTLETGVTI-HNVPIAWKTFGKLNDNVMVICHALTGSADVEDWWGPLILAFDTTKFFIFCANVLGSPYGSASPLTTGEQYGPEFPLVSVRDDVRLH-RVILDSLGIKSVAICIGGSMGGMQVLEWYVKNIVPIATSGRHSAWGISWGEAQRQSIYSDPFYADGYYVGLAAARMSALLTYRSRNSFESRFGRNQSYLRYQGDKFINRFDANCYIALTRKMDTHDLGRGRVLADIVIGIESDGL--FTISEQYELAEFIPNSEMVVIQSPDGHDGFLLEFDQ--INKNILRF-I--QRVLPDKTSLFGEADITQW Ustma22 LFPQ-FTLESGVTL-TNVPIAFKTWGTLADNALVVCHALTGSADVEDWWGPLMKVFDYSRFFIVCCNVLGSPYGSASSCTGHGWWGPEFPATTVRDDVRIQ-KLVLEYLGVESVAAVVGGSMGGMAVLEWYIQALVPLATSARHSAWCISWAEAQRQSIYSDPAFKHGYYNGLSAARMAALLTYRSRESFESRFGRRQSYLRYQGDKFVRRFDANCYIHLTRKMDSHDVARSRVLGFLVVSIQSDGL--FAPPEQMLIHQLIQGSHFVSINSSDGHDGFLLEFDQ--INLQVGHF-L--TRVLSHKHSVFGEIDVTRW Walse1 HFDT-FKLESGIEL-KNVPVAYKTWGKLNDNVMVICHALSGSADVEDWWGPLMKAFDPSRYFIYCGNVIGSPYGTVSPVTTGDLYGPEFPLSTIRDDVRLH-KRVLDGMGVQAISSVIGGSMGGMQTLEWYIRSIIPIATSVRHSAWCISWGEAQRQSIYSDPAYFDGFYSGLGAARMAAMLTYRSRDSFEARFGRKQSYLRYQGDKFTSRFDANCYIHLTRKMDTHDIAAEFALKLLVIGIESDGL--FTPFEQHQIGSA-PSAELVMIPSPDGHDGFLLEFEA--INEYVTKF-L--QNKLPEKTSVFGEADITAW Zygro1 EIPE-LTLESGVSI-RNFPIAYKSWGNLNDNCMVICHALTGSSDVSDWWGPLLMAFDPSRFLVICLNSMGSPYGSFSPLSTGKPYGPEFPLCTVRDDVKAH-RMVLESLGVKSVACVVGGSMGGMTALEWYVKNVIALATSARHSAWCISWSEAQRQSIYSDPKYRGGYYAGLSAARMSALLTYRSRNSFEKKFSRRQSYLRYQGSKFIGRFDANCYIAITRKLDTHDLARDRVLQSIVIGINSDGL--FTYSEQEVLAENMPHAHLEKIESPEGHDAFLLEFKL--INELMTRF-L--KEEAGKTESVFGEAEVTNW [Cluster2478.fasta_al_trimmed; alignment length = 101] Allma1 SYYFAIVGDSPIYELHQFVLHAALDFVDDNMYLRVVDKFFVSAFVSAGNIRFMLLHDSKNEDGIRNFFTDVHELYVKSLMNPFYEVNAFDLKVRTIARRYL Ashgo11 PFYFAIIGDNPIYELNPFILHASLDIIEDSCYLSKVDNFSITGYITYGNMKFVMIHGTQDDGMLKSFYQEVHELYIKTLMNPFYKVDTFDWKVKQLAKKYL Aspfu1 SYYFTILSDVPLFNMNQFIIHSSLDIVEENMYLKHIDTYYISAFLTPSGTRFLLLHQPPTEEAVRQFMNEVYENYVKTAMNPFYRQGVFRARVVAAGKKWL Aurde31 SHHLFIVSDTPLYSVIQMIAHASLDVIEDTMYLKGVDKFTVSAFVTPGNIKFILLHDGKNDEGIRAFFNDVWELYVKTTMSPFHMVNVFDVRVKASAKKNL Batde5 NSYFAIVGDSPLYEMNQFVVHAALDVVDEAMYLKVVDRFLVSAFVTPSGVRFILLHDTSNTDGIRNFFQECYELYIKVLMNPFTEINAFDQRIRAQGRKWL Botbo1 SHHLFLLSDTPLYTVIQMIANASLDAVEEAMYLKAVDKFTVSAFVTAGNMKFILLHESKNDEGIRSFFMDVWELYLKTIMNPFHTAHVFDVRVRMSAKKYL Botci1 SYYFAIVGDNPLFEMNQFIVHSSLDIVEEQMYLKCIDRFYVSCFMTGGNVKFMLLHSPSTEEAIKQFFTEVYENWVKTIMSPFYHVNVFRGRVAAAGKKYL Caeel EFYFAIIGDQPIFELNHYIGHAALDIVDEQMYLKMVDKFYVSAFVTASRIRFIMLHTHRADEGIKQFFQEMYETYIKHAMNPFYEIDAFEQKATLYGRKYL Canalb1 SYYFSIIGDNPLYELLPFIANSSLDLIDDVLNLGKIDQFSINAYVLQSQVKFILCYNSKEESTIKQFFQEVNELYTKCLMNPFYNVDDFDLKIKQLARKYL Cangl PQYFAIIGDRPLYELNPFILHASLDIVEDNCYLGKVDHFVVTAYLTYGGKKFVMLHGSSDDSMVRSFYQEVHELYIKTIMNPFYQEGLFDTRVKALAKKYL Capow TSYFVIVGDNPIYELNQFVLHSALDIVDENMHLKVVDKYFISAFVTVGNVRLMLLHDAKNDDGIKNFFQEVYEVYIKVLLNPFYEPNAFDAKVRAFAKKFL Catan2 SYYLAIVNDTPLYELHQFVLHASLDVVDDNMYLRVVDKFFVSAYVTAGNVRFVLLHSVKNEDGIRNFFVDAHELYVKTFLNPFHEIDTFDIKLRSLAKRHL Cioin NYYFVIVGDNPVFELNQFIAHASLDLVDEAMYLKTVDKFFVSAFVTASRMRFIILHNVRNEEGIKSFFNDVYDVYSKLVMNPFYKINAFEKKVNFYGKRHL CocheC53 SYTFSILSDVPLFTLVPFILHSALDIVEEPMYLKHIDKYYVSCWITGGNTRFLLLTRPRTEEAVKNFMVDVYEAWVKTIMNPFFAVGVFRQRVATAAKKYL Coere1 TYYFAIVGDSPLYELHQFVVHAALDLVEDACYLKTVDKYNVSAYVTPSNVRLMLLHEARSEDSIRSFFTDCHEFYIKTLMNPFYEPNAFDTKINTLAKKYL Conco1 ----------------------------------------------------------------------------------------------------- Conpu1 SHHLFLLSDTPLYSVIQMIANASLDAIEDAMYLKSVDKFTVSAFVTPGNMKFILLHESKNDEGIRLFFHDVWELYVKTALNAFHTAHVFDTRVRASAKKHL Copci SHHLFLLSDTPLYSVIQMIANASLDAIEDAMYLKSVDKFTVSAFITPGNMKFLLLHDGKNDDGIRSFFMEVWELYVKTTLNPFHTAHVFDGRVRACAKKYL Croqu1 SYYFVLSHRQPIYEVVQLVAHASLDALDDSMYLKNVDRFSVSALVPPGGPRLVILHEIKNEDGIKLFLLEAWEFLVRNMLSPFYETDAFDSRIKASARRFP CryneH991 ------MS------LCQMVAHMSLDSIEEALYLRGVDRHTVSAFI-PTGVKFVLLHDVKNDDGIRAFFVDLWEAYVKILLNPFFTVNAFEARVKSIAKRHL Crypa2 SYYFAIIGDNPLFELNQFILHSTLDVVEEQMYLKVVDKFYTSCFITGANVKFLLLHQPTTEEAIKNFFTEVYENWVKAVMSPFYKVNIFRQRVVAAGKKYL Debha1 SYYFTIIGDNPLYEILPFISNSSLDLIEDQFSLGKIDSFLINAFITQGNIKFLLCYDLNEDNSIKQFFTEVNELYVKCLLNPFYSVNDFDMRLKMLARKYL Dekbr2 SYYFAILGDAPVYELEQFILNSSLDILQDGLFSKNLDSFKILSYLTQGNGKFLIMTDLKHDESIRQFFIEIHELYVRNLLNPFYEINDFDTRVRALAKRYL Dicdi TFTFLIIGDNPLYEVLQYIAHGSLDIVEENMYLKIIDKFQISSFVTAGHIKFLLLHEKKDEDAIKNFFVEVHDLYLKILLNPFYEYNAFDAKVRKIGTKYF Dmel TYYFVIVGDNPIYELTQFIAHAALDLVDENMQLKSIDRFFVSAFITASQIRFIIVHDNKNDEGIKNFFNEMYDTYIKNSMNAFYRINMFEKKSEIFGRKYL Enthi NTYFVIIGDRLLYELNQFVILSALDFIEEKMYFKSIDVYHLSAFVTSGNIKFVLMSTSKTDDT-KGFFTAVYEDYVKIILNPFYELQGLNTHIKQLLKQYK Falba ----------------------------------------------------------------------------------------------------- Fomme1 SHHIFLLSDSPIYSVIQMIANASLDVIEDNMYLKSVDKFTVSAFVTPGNMKFIMLHEGKNDDGIRNFFMDVWELYVKTLLNPFHSAYVFDGRVRASAKRHL Fusgr1 SYYFAIVGDNPLFELNQFILHSSLDIAEEQMYLKCIDKFYISCFVTAGNVKFLLLHQPITEEAIKMFFTEVYENWVKAIMSPFYRANIFRTRVAAAGRKYL Galma1 SHHLFLLSDTPLYSVIQMIANAGLDVIEDTMYLKSVDKFTVSAFITPGNMKFVLLHEAKNDEGIRVFFMEVWELYVKTMVNPFHTAHVFDSRVRASARKHL Ganpr1 MSYFVVVGDNPLYELNQFIVHAALDMVDEEMYLKTVDKFFVSAYVTASGIRFMLLHDSPNSDGIRNFFTETHELFIKTLLNPFYELNTFDTKVKALGKKYL Gloin1 SFYFAIVGDNPIYELNQFIIHSALDLVEEAMYLKSVDKFHISAFISAGNIKFMLLHESKNEDSIRNFFNECHESYIKILMNPFYEINGFDTKVRYAAKRYL Hisca1 SYYFAILSDVPLFSMNQFIVHASLDIVEEAMYLKHIDTYYVSAFLTGSGTRFLLLHQPPTEEAIRQFMNEVYENWVKTVMSPFYRQGVFRGRVVAAGRKWL Klula1 MFYFTIIGDNPIYELNPYIVHSTLDIMEYNSYLGKVDSFAVSGFLTYGNIKFIMVHG--DDTVTRSFYYEVYELYLKTLMNPFYKVNAFDSKVRVLSKRLF Lacbi2 SHHLFLLSDTPLYSVIQMIANASLDAIEDTMYLKSVDKFTVSAFVTAGNMKFVLLHEGKNDEGIRGFFAEVWELYVKTMMNPFHTAHVFDSRVRASARKYL Lenti61 SHHLFLLSDTPLYSVIQMIANASLDAIEEVMYLKSVDKFTVSAFVTPGNMKFVLLHESRNDDGIKAFFNDVWELYVKTMLNPFHTAHVFDARVRASAKKYL Malgl1 SYYFCVVGDNLLYEHLQMIAHGSLDTLED------LDSN-ISNVCT--DIKFILLHQHKHEEGIRQFLMDVWELWVKVFMNPFQELDSFDARVRASAKRHL Mellp23 SLNVVIVGDKPIYQVLELIVNASLDDLNHSMYLKNLDQFSISALVPAGGIRLILLHEIKNDDGIRHFFLEVWELIVNIQLSPFYKLNQFDTKLKLSARKHL Mnele NYYFVIIGDNPIYELCQFVAHASLDMIDENMYLKIVDKFNVSAFVTAGKQRFIILHDVKNEDSIRQFFQEVYELYIKVAMNPFYEPNVFHQKLKVLCRRYL Monbr ----------------------------------------------------------------------------------------------------- Morel2 TCYFVMIGDNPIYELNQFIAHSALDMVEDQMYLKAIDKFFISAYLTAGNIKLLLLHDAKSEDAIRNFFNDCYELYIKTLLNPFYEPNAFDTKVRLSAKRYL Mucci2 NYYFAIVGDNPIYELNQFIIHAALDVVEEAMYLKSIDRFYVSCFVTAGSVKFMLLHDQKSEDSIKQFFTEVYELYVKVLMNPFYEKNSFDNRIKLVARRFL Mydma FYYFVIVGDNPVYELNQFIVHGALDLVDENMYLKVVDKFFVSAFITASGAKFMMLHDLRNDEGIKNFFQDSYETYAKLLMNPFYEYDVFERKLQNFGKKYL Neucr2 SYYFAIIGDNPLFELNQFIIHSSLDIVEEQMYLKLVDRFYISCFLTASNIKFLLLHQPPTEEAIRNFFAEVYENYVKAIMSPFYRTNVFRARVAAAGRKYL Orpsp11 ----------------------------------------------------------------------------------------------------- Pench1 SYYFTILSDTPLFNMNQFIIHSSLDILEEGMYLKHIDTYYITAFLTPSGARFLLLHQPPTEEAVRQFMNEVYENYVKTAMSPFYKQGVFRTRVTAAGKKWL Phybl2 VYYFAIVGDNPIYELNQFITHAALDVVEEAMYLKSIDRFFVSSFVTAGNVKLMLLHDQKSEDSIKNFFNEIYELYIKILMNPFYEKNQFDVRVKAVARRFL Picst3 SYYFSIIGDNPLYEILPFVSNSSLDLIEDQFNLGRIDSFLVYAFITQGNIKFILCFESSDENSIKQFFIEINDLYVKCLLNPFYAVNDFDLKVKLLAKKYL Plicr1 SHHLFLLSDTPLYSVIQMIANASLDVVEEAMYLKSVDKFTISAFITPGNMKFILLHESKNDDGIKSFFNDVWELYVKTMLNPFHTAHVFDTRVRASAKKHL Polpo ----------------------------------------------------------------------------------------------------- Pucgr2 SYYFVIVGDNPIYEVVQLVSHAALDTIDASMYLKQIDRFSVSAWIPPGGMRFVLLHEIKNDDGIKMFFLEAWESFVRHQLSPFYEINQLDTRIRTSARKFL Punst1 SHHLFLLSDTPLYSVIQMIANASLDVIEEAMYLKSVDKFTVSAFVTPGNMKFILLHEAKNDDGIKAFFTEVWELYVKTMLNPFQTAHVFDARVRASAHKHL Rhior3 ----------------------------------------------------------------------------------------------------- Rhoto1 SYYLVLVGDNPLYEVMQLVAHASLDVVEDGMYLKSIDKFTVSAWLTPGGVKIILLHELKNDEGIRLFLQDTWETYVKTLLNPFHELNTFDARIKASAKKHL Rozal11 NYYLVIVDDHPVYELIQFIAYSSLDVIDEGFYFKVIDKFFVSAHITPSGMRMVVLHDARNEDAIKNFLFDCHELYSRMLLSPFFDPNHFDSKVKALMKKYF Sacce1 PQYFAIIGDNPVYELNPFILHASLDIVEDNCYLGKVDHFAITAYISYSGMKFVMIHGNSDDNNMRSFYQEVHELYVKTLMNPFYKITAFDSRVRTLARKHL Salro GCYFVIVSDKPLYELHQFIAHSALDAVDQDMYLKVVDRFMVSAYVTPSKTRFLLVHDMKADDVIKGFFQDVHELYTKALANPLLRADRFHSRMDVLLRRFH Schco3 SHHLFLLSDTPLYSVIQMIANASLDVVEDAMYLKSVDKFTVSAFITPGNMKFILLHEGKNDDGIRAFFTEIWELYVKTMLNPFHTAHVFDARVQASAKKWL Schpo1 TAYAAIIGDNPVYELNQFIVHSSLDIVDQAFYMKTIDQFYISAYVTPSNMRFMLLHQNQSADNIKLFFQELHELYIKTLMSPFYQPNAFDLKVRSIARRYL Sorma SYYFAIIGDNPLFELNQFIIHSSLDIVEEQMYLKLVDRFYISCFLTASNIKFLLLHQPPTEEAIRNFFAEVYENYVKAIMSPFYKTNVFRARVAAAGRKYL Sphar --------------LNQFIVHAGLDIVEENLNLRVVDKFFTSAFVTAGGTKFMLLHDTRDDDNIKNFFTDVYELYVK------------------------ Spipu1 NSYFVIIGDNPLYELNQFIVHAALDVVDDSMYLKVVDKFYISAYITASGVRFMLLHDAANTDGIRNFFQDTHELYIKTLLNPFTEINSFDTKVRALARKWL Sporo1 ---------------MQLVAHASLDVVEDAMYLKSIDKFTVSVWLTPGGVKIILLHELKNDDGIRLFLQETWENYVKTLLNPFHELNTFDQRIKASAKKHL Stehi1 SHHLFLLSDTPLYSVIQMIANASLDVIEDAMYLKSVDRFTVSAFVTPGNMKFVLLHESKNDEAIRLFFNDVWELYVKTMLNPFHTAHVFDNRVRASAKKYL Tapde11 SFMLAIVGDNPLYTMNQFILHSSLDIVEEIMYMKSIDKFLISTFLTAGNIKLMLLHELRNDDGIKNFFNDVYELYTKTLMSPFYAVNVFDQRVRALAKKYL Thetr NSFFVMVGDTLLFELTHFVLFSALDVVDENMFLRKVDKFEVSAFVTAGNIRFLILHDARNDDGIRTFFTRVYDLYMKMALNPFYKLNSFAAKVRALADEHL Treme1 SFYLAIVSDSPLFQMQQMIAHASLDSVEENLYLKNIDRHTVSAFL-ATSVKFILLHDTKNDDGIRAFFIELWEVYVKVTLNPFHTVNNFEAKVRAAAKRNL Trire2 SYYFAIVGDNPLFELNQFILHSSLDIAEEQMYLKCIDKFYISCFVTGGNVKFLLLHQPTTEEAIKMFFMEVYDNWVKAIMNPFYKANIFRARVAAAGRKYL Umbra1 TYYFAIVGDSPLYELNQFIIHSALDVVEEALYLKVIDRFYVSAFVTAGNARLLLLHDVKSEDSIKNFFNEVHEMYIKVLMNPFYETNQFDSKVKFIARRFL Ustma22 SYYLVLIGDNPLYEELQMIAHSALDTIEDYLYLKSVDRITTSCFVLPGNVKMVLLHEHKHEDGIKNFFLDVWEAYLKVSMNPFQDPNAFDARVRTAAKKFL Walse1 IYHLYLLNDTPIFKVMDLVAHASLDVIEDNMYHKCVDKFSISAFVTPSSTRFVLLHQVKNDDNIRLFFQECWEAYLKTLLNPFYTSTGFQDKLVKSARKYL Zygro1 PQYFAIIGDNPIYELNAFILHASLDIVEDNCYLGKVDHFAITAYITYGGMKLVMIHGGPDDNMVKSFYQEVHELYVKTLMNPFYKVNAFDSRVRALAKKYL [Cluster2482.fasta_al_trimmed; alignment length = 93] Allma1 LHDGVVLLFWWALRTAVEQGWSEAKAQWFMDIADYLIAAVVEDIMNEEFKV-LLEDNSMAKSLFSLECASGDF-TDVDHAGPIVDEDGFTLVA Ashgo11 FALGVCMYVWDALSIAVENNWSAEKRDWVSSLLDLFIEETLLFAMADEFET-NVEDDSIAAGIINLQCEAGNY-NEMG-DVPELDEDGFEIVK Aspfu1 LDLGITLTIWPALTMAVQSNWSADKRDWLCGISDMILEDVLIQVMNDEFDV-VVDDDSVAAQIMAIQTARGEF-GDVDMDEPEVDEDGFTKVV Aurde31 FARGVIAILWPVLRLAVEQAWSAAKRRWLAGIVDAFVEEMLLQVLQDEFEV-VVDDDSVAKQIVQLDVQQSAV-D--DQDEPEVDDEGFTVVK Batde5 FEEGVIHMYWTALTLAYQNA-AAQPHLDLVATIDYFLAANLMSYFEDMFEV-EVEDGSIAKIIALMEIFVGRNAAEMENQMPIIDEDGFETVV Botbo1 FARGVIAILWPVLRLAVDQNWSAAKRTYLASIVDAFVEDLVLQALAEEFEV-VVEDGSVARDVVRLEVSEGKT-D----DEPVVDEDGFTLVQ Botci1 FQRSIVLSIWPSLSLAVTSLWSSDKREYIAGLIDLLIETILLQFMSDEFEV-----------------------SSIERH--------FQ--- Caeel LRNFTGRTLWSGYQLALDNSCTREKDKWFLELCEQLLEEWLTNILYHDFDL-ILDDDSIAFFLLEGENEAGIQ-Q-----QVVVDDDGWTTIT Canalb1 FELGVCMAIWEELTTAVDNLWSAEKRDWISGIIDLFIEETLLYAMVDEFDT-QIDNDSIGNLIVKLDAAQEKY-GEID-EAPIVDDDGFELVQ Cangl FELGCSMMVWDALDIAVDNQWSAEKRDWITGIVDLFLEETLLYAMVDEFDT-NVEDDSIATGIIQVDCAAQNY-QEND-KEPIVDDDGFELVQ Capow FIDAIDAVFWTALQLALEQGWARKVA-WMKDVIVQFIDQQLQAALEADFNM-QLEDNSVARLIVDAKIATGQS-QAAGDQGPQVDADGWEVVS Catan2 LHAGVTLMLWYALRAAVEHGWTEAKAQWFLDIAEYLLADVLEDIMSEEFQT-LLEDNSMAKMLYALECVKGDY-SDVDQ-GPVVDEDGFMMVS Cioin FYQSIQAILWTGLQLAVAHGFSSEKAQWLVGIETFFLEDFIDEIMATEFNT-LSEDDGISQEICNQYWKEGRYKEK-DTESDLIADDEWTTVT CocheC53 FDLGIWHALWANLTIAVQNQWSSEKRDWLAGISERFVEIMLLQVLEDEFGV-RVEDDTVAREIMTIEIGEGST-A--EMTEPEVDEDGFTTVV Coere1 FVEGVDHILWTALELAVQHEWTQDKREDMVDIVEHFLEELLLDIMDGDFSV-ALDDQSVAKLICTVECKTGNF-T------------------ Conco1 FREGVTLLFWDALKLAVQMEWSKEKRDWMIDVVEYFIEDILNQIMSDEFET-VLEDDSVAKQCIQLEVVTGNH-ESDEMQ------------- Conpu1 --------------------------------------------------------------------------------------------- Copci FARGVIARLWPTLKIAVQESWSAQKRSWMASVVDTFIEELLLQIMSDEFEV-SIEDGSVARDLVQLETREGRD-AEMDEDEPEVDEDGFTLVK Croqu1 FARSVLSLLWPALQLSFENSSQSVLISELATLVGAFLEDFLLGWIFGTLDV-RIEDESISNELIGLMAYQQEG-TKV---SPVVDEDGFTLVT CryneH991 FARGTLALLWPALTIAVSEQWSAEKKTWIASLIDEFIIDLLTQIMEDEFEA-RLEDGSVASDIVRLLTEEKPE-SEVDGGEPVVDDDGFTLVQ Crypa2 FEQAVALSLWPALTLAVQNNWSADKRDWFAGVASQFIEELLLQVMLDEFEV-NVDDDSVAVEIIRLQCAKGSF-EDEDMTAPEVDEDGFTKVT Debha1 FELGVCMCIWDELNTAVINSWSADKRDWISGVIDLFIEETLLYAMVDEFDT-EVDNESIADMIVKIEVYLKKY-DDVD-EAPIVDDDGFELVQ Dekbr2 FELGVSMIIWETLQTAVDNLWSADKRDWMTGIVDSFIHESLFNAMQDEFGV-VVEDESVGQRVVQAECLAGNF-DDVD-EEPEVDDDGFTVVH Dicdi FDQAVLRIFWTALQLAITNEWTSERAEDMRQVLDLFIEKILDECLSQDLNT-VAEDDSVATLIIQCLAINGAYNDMMDDDEP--DEDGWVTVN Dmel FRVIVEKIFWQDLRLAVEHGM----------IMDYTLVEVLEELMDQEFNT-LCDDDSICRNLLRYMAQQNQF--GQGDEEFVEPEDGWTTVR Enthi FEQSVRGLMWSTLRLCVEHQFSQQKKDSMVQIISKYIIDFLYNFFEQKMNT-SCEDESVAELISRLECIVGDT-TNTDSSESSVKEEEV---- Falba LAEAVGLVFWSLLQVAVANEWSREKAEWLEELVEFVVEDFLFDILGEEFSC-VAEDGSVSKTVCKIELKEDTL-TETEGDAPDVDEDGFELVT Fomme1 FARGVIARLWHALRLAIDQSWSTQKQTWMASIVDEFVEEMLLQIMDDEFDV-ILEDGSVARDIVSLEAEPRMK-AESDGDEPEVDDEGFTRVT Fusgr1 FEQAVAYALWPALTLSVQNNWSADKRDWFAGVVELFVETVLLQVMVDEFEV-NVDDDSVASNILRASCTLGTY-DDVEMDQPQVDEDGFTMVT Galma1 FARGVIARLWEILRIAIQENWGTSKRTWLAGIVDSFIEELLLQVMADEFDA-VLEDGSVAQDIVRLVTRLSKQ-DDEEEE-PEIDEDGFTLTD Ganpr1 FAHAVTLVFWTALQLSLQN--VRDPRDTLTHTVDFFLRDNFESYFDQVFNV-DCEDGSVGRDLVALIVRDGKS-DDLDGSEKVVDEDGFELVQ Gloin1 FTQGVSLLFWTALKLAVDMQWSEDKRDWLIDIVDYFLETILNQVMTDEFNT-LLEDDSISQDLIKIECIQGNY-STMESD--IIDDDGFTLVT Hisca1 FDLGITLILWPALNLAVQSSWSSDKRDWLCGISDLFIEDVLIQVMNDEFDV-VVDDESIGRRIMEVETQMGDF-TDVEMEEPIVDDDGFTKVV Klula1 FELGVSMMIWNALDVAVVNQWSAEKRDWVTSIVDLFIEETLVYAMFDEFDT-NVEDESIAAAIIIIECAQENY-SNMD-EEPVLDEDGFELVQ Lacbi2 FARGVIARLWATLRIAVQENWGAEKRTWLASIVDAFIEEMLLQVMADEFEA-VVEDGSVAQDIVKIQTRIGKD-DEMEEDGPEVDEDGFTVVR Lenti61 FARGVIARLWPALRIAVDQSWSASKRTWLASLVDDFVEDRLLQVMADEFDA-VLEDGSVAKDVMRLEVTQGTD-AEGPGEEPEVDADGFTTVK Malgl1 FARSVYIILWPALRQAVLEQWSEEKREFLLSVCDEYLTELIESYVMEEFDC-ELEDDSVAGHICLA---KGDE----HQTQPIIDEDGFETVQ Mellp23 FARSVLSVLWPALELSFEHSSKDELISELASLVGAFLEDFLLAWCFGTLDV-RIEDDSVVKELLGVEAYEAEG-TDV---SPVVDEDGFTLVT Mnele VELVAKSALWTSLQLSIQHGFAAGKLSQLTDII---IEDLLESSAYHDFNF-IDEDGSLAKAIVTCELKHGKVSEDITIKDPVIDEDGFELVQ Monbr --------------------------------------------------------------------------------------------- Morel2 FREGVEYLFWTALKLAVDGEWSAAKRDWFVDIVDYFLEDILLQIMNDEFSI-MLEDKSISKVLEQLDCTHGKY-DDVEMG-PIIDEDGFETVV Mucci2 FEEGVSYIFWTALKLAVEQDWSAEKREWFIDIIDHFVEDILAQIMTDEFNA-TLEDDSVAKHLVLLQCINGNY-EDDEMD--LVDADGWEIV- Mydma FAYAIKKAFWSVLQISREHGFSFEKEEWLYDVLQIFLEDFISEAIFNEFDT-VVEDGTLCKQLCGFMCVNQQYQQEMETD-----DKEWKVV- Neucr2 FEQGVAIALWPALSLAVQNNWSADKRDWFAGVVDLFIETVLLQVMLDEFEV-NVDDDSVAEQILRVGCLKGKF-DDEEMGEPEVDEDGFTKVV Orpsp11 --------------------------------------------------------------------------------------------- Pench1 LDLAITLTLWPALSLAVQSNWSSEKRDWLCGISDMLLEEVLIQVMNDEFDV-AVDDESVADLIMELQTDRGEF-GDVEMGEPEVDDDGFTKVV Phybl2 FVEGVTYIFWTALKLAVEQDWSAEKRDWMIQMVDYFIEDILIQIMSDEFQT-LLEDDSIAKHLVLIQCITGNF-TDQDME--QPDEDGWLTV- Picst3 FELGVCMAIWEELNTAVENSWSGEKRDWLSGVIDLFIEETLLYAMVDEFDT-EIDNDSVAALVMKFDVSLEKY-AEVDEEGPIVDDDGFELVQ Plicr1 FARGVIARLWPALRLAVSNSWSVSKRTWLASLVDAFVAEMLAQVMEDEFDC-TLGDGSVARDIVKLEVARGGT-E--GGGEPVVDEDGFTLVQ Polpo FDQAVKRVFWTALQLAVQNAWSEEKAEDIRQILDLFIMSILEDRLSNELNT-IAEDDSVSEIIIQIFCCKGMFNE-MEDDEP--DEDGWITVG Pucgr2 FARSVVDLLWPALQLSFEQSAQDSARSELATLVGAFIEDFLLGWVFGTLDV-RIEDESITRDLLNLHAVRSSG-QNI---SPTIDEDGFTLVT Punst1 FARGTIARLWPALRVAVEQGWSAEKRTWLASLVDAFVTEMLLQIMEDEFDC-NLEDDSVARDVVKMDAEAGRE-EMEDSDEPEVDEDGFTLVK Rhior3 FEEGVGYILWTALKLAVEQDWSAEKRDWMIDIVDIFIEEILSQIMVDEFQV-ILEDDSVAKHLFGLQCVQGDF-TDQDME--LVDEDGWETV- Rhoto1 FARSALDLFWPALRLAISHGWGGQGKTHLAEVVDLFIEQTLLYVIGNEFDV-DLEDGSVARDLVNLECLQRVRAGAIE--EPVVDEDGFELVQ Rozal11 --------------------------------------------------------------------------------------------- Sacce1 FELGVSMVIWDALDVAVENSWSAEKRDWITGVVDLFIEETLLYAMIDEFET-NVEDDSIAVEVINIDCFNLNY-NEMD-EEPIVDEDGFELVQ Salro FQAGVGHAFWDVVGKAIDNQWTDEKVEWMKEVAEWFVAWYIGEIFTNEFNV--MNDGSIAAVLVDLQANNNTA--DGNANEEQEEDDGWTTVG Schco3 FARGVIARLWEDLRVAVQENWAAAKRTWLAGIVDAFVEEMLLQVMEDEFDT-VIEDGSVAKDIVRVETRRGQA-AEIDE-EPEVDEDGFTTV- Schpo1 FEYAVGVLLWPVMKQAVEEEWTADKRDWMAGLVDYIVEELILQVLQDEFNVGSIEDDSLAQDLVNVAACEDNY-EQNQQEGPIVDDDGFTVVQ Sorma FEQGVAIALWPALSLAVQNNWSADKRDWFAGVVDLFIETVLLQVMLDEFEV-NVDDDSVAEQILRVGCLKGKF-DDEEMGEPEVDEDGFTKVV Sphar --------------------------------------------------------------------------------------------- Spipu1 FTDAVQCVFWTALQLALDHQMAERPQELLEHTCAFFIAENLKDFFDEVFNA-ELDDGSIGKTLVRLVVVEGKT-EEVDSGDPVVDEDGFELVQ Sporo1 FARSTIDLLWPALRLAITHGWGG-------------VEETLKWSISQQFDL-DLEDGSVAKDLIQLECIKRVLNHEVETAEPVVDEDGFEMVQ Stehi1 --------------------------------------------------------------------------------------------- Tapde11 FELAVSLYLWPALSLAVENEWSAEKRDWLAGVADLFVEDVVTQVLSDEFSV-ALEDDSVAVAIVAADCQQARF-EEVD--EPVVDEDGFELVQ Thetr FTHLVAAFVMPAMSYAITNSMAEDVANGLADLVDLFVEDIINAALES-VAM-LVEDDSVARLIVNVQVIAGNR-EPDGDAAAATDDDGWTTVS Treme1 FARGVIALLWPALTIAVREEWSADKKTWLASIIDLFLADLISQVMSDEFEA-NIEDNSVANDIIRLNTSPAPH-IELDDDEPQVDEDGFTLVQ Trire2 FEQAVACALWPALTLAVQNGWSADKRDWFAGVVDLFVETVLLQVMVDEFEV-NIDDDSVARSIVKAECAIGEFNEDVDMDAPEVDDDGFTKVT Umbra1 FTEGLNYVLWSALKLAVEQDWSEEKREWMAELVEYFVEDILVQIMSDEFHT-DLEDGSVAKHLVSMQCIHGDF-SAMDVEGPIIDEDGFELVT Ustma22 FAKSIMLTFWPAMRLAVSEEWSADKRDFLLSLCDEYLADVLEHYMVDEYEA-RLEDGSVAGRIVGLDFARAQA--GLEQDQPIIDEDGFETVV Walse1 FARSTISILWHALKMAVAESWSEAKRIWLIGVVDMYTEEILSQAFFDEFGA-HLEDGSIAGQLRKAEAVVGDM-SHMQDTEKIIDDDGFEVVQ Zygro1 FELAIAMMIWDDLEIAVENGWSADKRDWLSAIVDLFIEETMLYAMVDEFDT-NVEDDSIAVGIINRECAEGNY-SNMD-EEPVVDEDGFELVQ [Cluster2490.fasta_al_trimmed; alignment length = 48] Allma1 MHLMYHLDRVYTLKKMTKSAHPARFSPDDKYSRHRVTIKKRFGLLPGV Ashgo11 MHLMYTLGRVYTLEKITKSAHPARFSPDDKYSRQRVTLKRRFDMLPR- Aspfu1 ------------------------------------------------ Aurde31 MHLMYTLDRLYTLKKLTKSAHPARFSPDDKFSRHRVTIKQRHGVLLTQ Batde5 MHLMYYTARVYTLKKVTKSAHPARFSPDDKYSRHRVTLKKRFGVLLTQ Botbo1 MHLMYTLDRIYTLKKVTKSAHPARFSPDDKFSRHRVTIKKRHNILLPQ Botci1 MHLMYTLDRKYTLKKVTKSAHPARFSPDDKYSRHRVTLKKRYGLLLVQ Caeel MFLRYFLDRVYTLKRQTLTAHPARFSPEDKNSKYRIIIKKRFGLLPTQ Canalb1 MHLMYTLDRIYTLKKITKSAHPARFSPDDKYSRQRVTLKKRFGLLPTQ Cangl MHLMYTLDRVYTLKKITKSAHPARFSPDDKYSRQRVTLKKRYNLLPQ- Capow MYLMYY-ERQYTMKKPTKSAHPARFSPDDKYSRHRVTLKKRFGILMTQ Catan2 MHLMYHLNRVYTLKKMTKSAHPARFSPDDKFSRHRVTIKKRFGLLLNN Cioin ------------------------------------------------ CocheC53 MHLMYIPDRIYTLKKVSKSAHPARFSPDDKYSRHRVTIKKRYGLLLTQ Coere1 MHLMYSVDRVYTLKKITKSAHPARFSPDDKYSRQRVTLKRRFGLLPTQ Conco1 MHLMYYKNRVYTLKKATLSAHPARFSPDDKFSRHRVTFKKRLGILPTQ Conpu1 MHLMYTLDRIYTLKKITKSAHPARFSPDDKFSRHRVTIKKRYGVLLTQ Copci MHLMYTLDRVYTLKKITKSAHPARFSPDDKFSRHRVTVKKRYGVLLTQ Croqu1 MHLQYILDRVYTLKKVTKSAHPARFSPDDKFSRHRVTVKKRFGVLPTQ CryneH991 ---MYTLDRVYTLKKPTKSAHPARFSPDDKFSRHRVTIKKRFGILPTQ Crypa2 MHLMCNVDRVYTLKKVTKSAHPARFSPDDKWSKHRVLLRKRFNRLPSA Debha1 MHLMYTLGRVYTLNKITKSAHPARFSPDDKYSRQRVTLKKRFGLLPTQ Dekbr2 ------------------------------------------------ Dicdi MHLMYYNDRVYTLKKATYSAHPARFSVDDKYSRERIALKKRFGLLLTQ Dmel MYLMYTINRVYTLKKPTLSAHPARFSPEDKYSRQRLTIKKRFGLLLTQ Enthi -MLLYYCDKQYTMKTYVRSAHPAKFSPVDPYSKYRIATKKEFGLLPTS Falba ------------------------------------------------ Fomme1 MHLMYTLDRVYTLKKVTKSAHPARFSPDDKFSRHRVTIKKRFGVLPTQ Fusgr1 ---MYTLDRLYTLKKVTKSAHPARFSPDDKWSRQRVTLKRRFELLLTQ Galma1 MHLMYTLDRVYTLKKITKSAHPARFSPDDKFSRHRVTIKKRYNVLLTQ Ganpr1 MHLMYYTDRVYTLKKPTKSAHPARFSPDDKYSRHRVTLKKRFGVLLTQ Gloin1 MHLMYYTDRIYTLKKITKSAHPARFSPDDKFSRHRVTLKKRFKILLTQ Hisca1 MHLMYTLDRIYTLKKVTKSAHPARFSPDDKYSRHRVTLKKRYRLLLTQ Klula1 MHLMYTLDRIYTLKKITKSAHPARFSPDDKYSRQRVTLKKRYNLLPN- Lacbi2 MHLMYTLDRIYTLKKITKSAHPARFSPDDKFSRHRVTIKKRYNVLLTQ Lenti61 MHLMYTLDRIYTLKKITKSAHPARFSPDDKFSRHRVTIKKRYGILPTQ Malgl1 MHLMYTIGRQYTLKKMTRSAHPARFSPDDKFSRHRITIKKRYGILPTQ Mellp23 MHLQYTLDRVYTLKKVTKSAHPARFSPDDKFSRHRVTVKKRFGVLPTQ Mnele ------------------------------------------------ Monbr MFLMYYLNRVYTLNKPTISAHPARFSPDDKYSRHRVTLKKRFNILMSQ Morel2 MHLMYTMSRIYTLKKVTKSAHPARFSPDDKYSRHRVTLKKRFGLLLTQ Mucci2 MYLMYYLNRVYTLKKPTKSAHPARFSPDDKFSRQRVTIKKRYNILLTQ Mydma ------------------------------------------------ Neucr2 ---MYVPARQYTLKKVTKSAHPARFSPDDKWSRHRITLRRRFAVLLAQ Orpsp11 ------------------------------------------------ Pench1 MHLMYTLDRVYTLKKVTKSAHPARFSPDDKYSRHRVTLKKRYGLLLTQ Phybl2 MYLMYYLNRVYTLKKPTKSAHPARFSPDDKFSRQRITIKKRYNILLTQ Picst3 MHLMYTLGRIYTLKKITKSAHPARFSPDDKYSRQRVTLKKRYGLLPTQ Plicr1 MHLMYTIDRVYTLKKITKSAHPARFSPDDKFSRHRVTIKKRFNVLLTQ Polpo MHLMYYV-RKYTLK-FAYSAHPARFSVDDKYSRERIALKKRFNVLLTQ Pucgr2 MHLQYTFDRIYTLKKVTKSAHPARFSPDDKFSRHRVTIKKRFGVLPTQ Punst1 ------------------------------------------------ Rhior3 MYLMYYLNRVYTLKKPTKSAHPARFSPDDKFSRHRITIKKRYNILLTQ Rhoto1 MHLMYSLGRLYTLKKPTRSAHPARFSPDDKYSRHRVTIKKRFGILLTQ Rozal11 MHLMIYNGRRYTLKKATRSAHPARFSPDDKYSRHRVTLKKRFGLLLTQ Sacce1 MHLMYTLGRIYTLKKITKSAHPARFSPDDKYSRQRVTLKKRFGLVPGQ Salro MFLMFYLDRVYTLKKPTQSAHPARFSPDDNYSRHRVTLKKRFGILPSQ Schco3 MHLMYTLDRVYTLKKITKSAHPARFSPDDKFSRHRVTIKKRFGVLPTQ Schpo1 MHLMYYLNRVYTLKKVTKSSHPARFSPDDKYSRQRYTLKKRFHVLLTQ Sorma MHLMYVPARQYTLKKVTKSAHPARFSPDDKWSRHRITLRRRFAVLLAQ Sphar ------------------------------------------------ Spipu1 MHLMYYLDRVYTLKKVTKSAHPARFSPDDKYSRHRVTLKRRFGLLPTQ Sporo1 MHLMYSLNRVYSLKKPTKSAHPARFSPDDKYSRHRVTIKKRFGILPTQ Stehi1 MHLMYTIDRIYSLKKITKSAHPARFSPDDKFSRHRVTIKKRYGILPTQ Tapde11 MHLMYSADRVYTLKKITKSAHPARFSPDDK---QRVTLKKRFGLLLTQ Thetr MYLRFYLDRVYTLKKNTLSAHPARFSPDDQYSRHRITLKKRFGLLPTQ Treme1 MHLMYTLDRIYTLKKVSKSAHPARFSPDDKFSRHRVTIKRRFGILPTQ Trire2 MHLMYTLDRLYTLKKVTKSAHPARFSPDDKWSRQRVTLKRRFNLLLTQ Umbra1 MHLMYTLDRVYTLKKITKSAHPARFSPDDKFSRHRVTLKKRYNVLLTQ Ustma22 MHLMFTEDRIYTLKKITKSAHPARFSPDDKFSRHRVTIKKRFGILPTQ Walse1 MHLMFSSDRVYSLKKITKSAHPARFSPDDKYSRQRVTIKKRFGILPTQ Zygro1 MHLMYTLGRAYTLQKITKSAHPARFSPDDKYSRQRVTLKRRYGLLPGQ [Cluster2512.fasta_al_trimmed; alignment length = 47] Allma1 IKKIMQLDEDVGKVAQATPVSKALELFMQALIDESHMKQAIDQFDFL Ashgo11 IKKIMQTDEDIGKVSQATPVGRSLEFFIAMLVDKSIMKKTIEKFDFL Aspfu1 IKRIMQADEDVGKVAQVTPISKALELFMISLVTKAHLKQAVEVLDFL Aurde31 IKRIMQKDEEVGKVAQATPVSKALELFLARLVDEAHLKQAIEILDFL Batde5 IKKIMRSDDDVGKVAQVTPLSKALECFLSSMVEATHVKRTIEKFDFL Botbo1 IKKIMQKDEEVGKVAQATPISKALELFMGSLVEEMHLKHAIDTFDFL Botci1 ----------------------------------------------- Caeel ----------------------------------------------- Canalb1 IKKIMQSDEEIGKVAQATPVGRALEIFMANLVEVSHVKSAIEQFDFL Cangl VKKIMQSDEDIGKVSQATPVGRSLEFFMALLVKKSVLRDTIERFDFL Capow IKRMMQKDDEVGKIAQGAAVGKAAELFMQHLLKQLHLKECVQMFDFL Catan2 IKKIMQSDEDVGKLNQATPISKALELFMQSLLTAAHMKAAIDKFDFL Cioin IKKIMQTDEEIGKVSAAVPVSKCLEMFLASILQHTHLRECISMFDFL CocheC53 IKRIMQADDDVGKVAQVTPVSKALELFMISLVTKAHLKQAIDRFDFL Coere1 IKKIMQMDDEVGKMAQATPVSKSLELFMESIIDDVHLKRCIECYDFL Conco1 IKKIMQTDEDVGKMSHATPVSKALELFIKSLCEATHLKQTVEQFDFL Conpu1 IKKIMQKDEEVGKVAQATPVSKALELFLAMIVDESHLKHAVEMLDFL Copci IKKIMQKDEEVGKVAQATPISKALELFLNLIIEESHLKHAVEMLDFL Croqu1 IKKIMQADEDVGKVAQATPLSKAVEMFMQSLVKAAHLKQAVESFDFL CryneH991 IKRIMQLDEEVGKLASATPVSKSLECFIQVLLDESHLKLMIPSFDFL Crypa2 IKRIMQADEEVGKVAQQTPIGKALELFMIQLVSKSMLKHVVDQWDFL Debha1 IKKIMQSDEDIGKVAQATPVGRALEIFMANLVEASHIRSAVEQFDFL Dekbr2 IKKLMQSDEDIGKVAQATPVGRALELFMCTLVEKAVLKKTIEKFDFI Dicdi IKKIMQKDEEVGKIASATPISQCLELFMADLVMKTHLKECISTFDFL Dmel IKKIMQSDEEIGKVAQAVPVSRTLELFVESLLTKTHMRQCIKRFDFL Enthi VKRIMQEDEDVGKMSGNVPMARATELFLVDLIKKTHLHECVPVFDFL Falba IKRIMQQDDEVGKVSLAAPMSKALEVLMRELLRGAHFKRAVTEFDFL Fomme1 IKKIMQKDEEVGKVAQATPVSKALELFLGMLVEEAHLKHAIDMLDFL Fusgr1 IKRIMQADEEVGKVAQQTPIGKALELFMIQLVTKSMLKQVVEQWDFL Galma1 IKKIMQKDEEVGKVAQATPISKALELFLGLIIEESHLKHAVEELDFL Ganpr1 IKKIMRVDDEVGKVAATTPISKAVELFLQSLIDEAHIKDVVDSFDFL Gloin1 IKKIMQMDEDVGKVAQATPVSKALELFMQSLIDHAHLKKTIEQFDFL Hisca1 IKRIMQADEDVGKVAQVTPISKALELFMISLVTKAHLKEAIEVLDFL Klula1 IKKIMQTDEDIGKVSQATPVGRSLEFFIALLVDKSIMKKTIEKFDFL Lacbi2 IKKIMQKDEEVGKVAQATPISKALELFLGMIVEEAHLKHAVEMLDFL Lenti61 IKRIMQKDEEVGKVAQATPVSKALELFLAMIVEEAHLKHAIDMLDFL Malgl1 IKRIMQADEDVGKVAQATPVSKALELFMQDIVESAHLKRAAETFDFL Mellp23 IKKIMQADEDVGKVAQATPLSKAVEMFMESLVRASHLKQAVEAFDFL Mnele IKKIMQSDEEVGKVSAAVPVSKALEMFLESFLENAHLKQIINKYDFL Monbr VKKIMQSDEEVGRVAAPAADSRLVDVFADELVRAGHLKQVIEEYDFL Morel2 IKKIMQMDEDVGKVAQATPISKALELFMQSLIDEAHLKKTIDQFDFL Mucci2 IKKIMQLDEDVGKVAQATPISKALELFMQSLIDQAHLKKTIDQFDFL Mydma ----------------------------------------------- Neucr2 ----------------------------------------------- Orpsp11 ----------------------------------------------- Pench1 IKRIMQADEDVGKVAQVTPISKALELFMISLVTKAHLKQAVEVLDFL Phybl2 IKKIMQLDEDVGKVAQATPISKALELFMQSLIDQAHLKKTIEQFDFL Picst3 IKKIMQSDDEVGKVAQATPIGRALEIFMANLVEVSHIRSAIEQFDFL Plicr1 IKKIMQKDEEVGKVAQATPVSKALELFLAMIVDESHLKHAVEMLDFL Polpo IKKIMQKDEEIGKIALATPISQCLELFMCDLVQKTHLKACISTFDFL Pucgr2 IKKIMQADEDVGKVAQATPLSKAVEMFMQSLVEAAHLKQAIPAFDFL Punst1 IKRIMQKDEDVGKMSQATPIPKALELFLGQLVDEAHLKHAVEMLDFL Rhior3 ----MQLDEDVGKVAQATPI----------LIYQSHLKKTIEQFDFL Rhoto1 IKKIIQADEDVGKVAQATPISKAIELFLASLVESCGLKRAVAMFDFC Rozal11 VKRIMQVDEEVGKVSQLSTI----------LVYKSVLKMAVEQFDFL Sacce1 VKKIMQTDEDIGKVSQATPVGRSLEFFIALLVKKSILKKTIEKFDFL Salro IKKIMQTDEDVGKVSTGTPVSAVLEAFITDLLDQTHLKEAVPKFDFL Schco3 IKKIMQKDDDVGKVAQATPVSKALELFLKTIVDESHLKHAVEVLDFL Schpo1 IKKIMQADQDVGKVAQVTPVSKALELFMQSIIQESHLKHAVEQFDFL Sorma ----------------------------------------------- Sphar VKRIMQTDEDVGKVAMATPVSKTLETFLEDIILKTHLKEVIPPFDFL Spipu1 IKKIMRLDEEVGKVAQATPISKALELFMQSLIDEAHLKRTIEKFDFL Sporo1 IKKMIQADEDVGKVAQATPIAKALELFLASLVQASGLKRAIPTLDFC Stehi1 ----------------------------------------------- Tapde11 IKKIMQADEDVGKVAQVVPVSKAVELFMASLIQEAHLRMAITMFDFL Thetr IKAIIQSDPEVGRVAPEASFSKAIEFFLDDLVQSLHVKAMVPLLDFL Treme1 IKRIMQMDEEVGKLSASVPHPKSLERFMQSLLEEGHLKTAIPNFDFL Trire2 IKRIMQADEEVGKVAQQTPIGKALELFMIQLVTKSMLKQVVEQWDFL Umbra1 IKKIMQMDEDVGKVAQATPISKALELFMQSLIDQAHLKKTVEQFDFL Ustma22 IKKIMQADEDVGKVAQATPVSKALELFMASIVEETHVKRTVETFDFL Walse1 IKKIMQMDDEVGKVAQATPVSKALELFMQALVDETHLKQSIEQFDFL Zygro1 VKKIMQTDEDIGKVSQATPVGRSLEFFIALLVKRSVMKETIEKFDFL [Cluster2513.fasta_al_trimmed; alignment length = 326] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 GTKR--VDVTAPSVAVADATFETKA--ADSYVLHGENQKLEYEGRVQYMLGVYDPSSKSIELYQISKSKKRLAQ-ADARTMRTALGQAFGTKKAKKAIADLER-NRIDIVGSVRAAAKDLPTQQEMAATISE-DRP--IPPPNVDATDVEQIYPVRSII--PQHEWNFIVGPIMKEQQRLQML-PSAYITKKLPTLTQVQMEKLQL--LYYLSLLLGVENLLEADTLVDGILERFTVKDRSFAIDPQREDKLLCYILALIMHLFAHEL-GLKPSKLVNLLRTMGATVKTVAQAQAGIPKSAASTYK-IATLKVPFKLPENKRGKAA Aspfu1 DKKRKRLSASVLVPVISNLRFTKARANSELLLQSSEHPKLDFVGR-KHYVAVVDPEKKTWQLVEVRGAIRRMR--DEESAQRTELTNTFGTKQSRKAAQSMAE-NAQLILSSMPAATDIASKAAAVQAQVQA-NKP--IPQANLDATHPADVYPIDVLVPNGLVTLRQLVKEWADTSAGLPVA--SRYVSRRVEAVV-SGN-TTHLQILRFILLLLEFEELRRPDPVIDALRRKFAP----SHLTKNDLTFLHTTICALSLHILRDDL-RLESATILQYFRELGCRVDRESEFAKNIKGGKAAAARRIARLKIPVEFPKSRGGRR- Aurde31 TKKRKRLKVKSIGPRLADTAFN--SAT----LIAGETPQVEFQGQEQYLVGIYDKTTNTLCVRRLERRVKRLKA-AADAQARAELGSTFGTKKAQAAIRAAAR-NKVDLQARIEVQTKALPTKEEAEDRADA-ERL--VPPYDLSATQVQDAYPLNQLI--PDAEMSVIVRKLQDAAERRMLL-PNGWLGHMLDSLFAERPDRTKLKIVWYVSALLAFAALYDPQAVVDGLAARFME-DAQLQLTPAMETKLATWTLALMLHAVAQTVNNAPVPKVIGWFKALGCKVGPAAERQKGVEESD--TAK-WAMLRAPLEFPKKAK-PTQ Batde5 KLKAER--------YLASLQFDPVSENKKRRLAVAETAIMEYVGEPNYIVGILDKASGVMSLHDMTSIVKSQKL-IGEKAARNKLGQTFGSKKRKKNIQDLEL-NKVDITNKIQETSKVLPSREMITSTMFA-DRN--IPPCHMDAETPDKVYRLEDLA--PTQIMNTIIKLVWKAEEIVKQVQGTSWILKCLITTV-EQKHKSHAKLLVFVSMLMKL-ELSKNQIVADHVTSIFTEGNKRLCISNMLKDKLLAYILAITLHIFSSDL-LISPLKATTIAKEMGCQIKRPVDSVR--------TVK-HAVLVLPLSFHTRR----- Botbo1 SKKRKRISVAEIGPVIAETPFQ--DATKQTTILAGQTDTVAFVSSDQYMIGVYDRSTNSVVLRHMAREVKSLK--SNLQQARNALGETFGTKKAKAAIRAAER-NKVDLQDSIDANTVSLPTQEQAKATVDS-HRP--IPPVNIAAQTPSEVYNINDIA--LENELDAAVSSLIS-RER-NVL-PSKWLNAHLEKILAKKPSKKKLKLVFFISSMLAFAALQKPSIILDGLLARFTEGSAKSTMTEDSRTRLLTHMFALCLKLIAADL-QMPQTQISQLFKALGCTVESKAERERKMSLAEARENR-KARLKIPLVFPKKSG-PAR Botci1 SKKRKK----SWAPVIASISLQKPRKNKEVLLHSSEHPKLDYTAR-KHYVGVYDPKTGKLEVMEVRGSVRAHQ--TEAEELRNDLGETFGTKKAKKAIASVTE-NAISIIASMAEATSGMASRKDLEEQADA-AKP--RPKADLTAKDIKDVYTVDSLI--GSDIFKSVVLEWEQSKAKKNIT--SRYVSARI--VS-ATAGVNKLRVLRYLLLLLDLDEMKTPQSVIEDVRRKYSD-----VMSKFKSDLLITHACALACLVLQLDL-KLETKEMTQYFKEIGARVVARRKALDD----KAAAQRRTAKLKLPLDFPRPFGRRG- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------IKVNSPVATVGEVEFDHKK--RDDYVLHGETDTLDYNGTSEYVVAVFDPNSKSVELYKTAKKNRVYKS-AGIRTQRNALGEAFGTKKAKSAITNLEK-NRIDIVDTVKESTRDLPAQE---DGV---DRP--APLANVDATNVEDIYPLENII--PEKDWQYLVSSILTA---LEKL-PSEFIAKQLPILISKNTEKLQM--LFYASLLLGVQSLMTSEILVDGILDRFAIKDKSFTIDPYHEDKLLTYLFILLLHILSKDL-KLKNTRLVGLFRALGAIIKTVGEAEAGIPKSAVGTYK-IATLKVPFKLPETRRGKRR Cangl GEKR----IDSPSVVVSDTEFQKRK--QDQFVLHGENERLEYDGETQYVVGLYDKQSGKINLYRVSKFSKNLKSKGDTRAMRNALGEAFGTKKAKKAIADLER-NRVDIVDSVKTASKDLPTRAELQENVSASNRP--TPVANLDATDVEQIYPVENII--PKKELQFIVGPILKEEKKLELF-PSKYVAKKLETLTQSQMEKLQL--LYYLSLLLGVDKLLEPELLIDGILDRFTIKNRSYFIDPQNEDKLLCFILTIVMHLLAQEL-GIKPSRIVNLFRILGAIVKTVSQAEAGIPKSAAATYK-IASLKVPFKLPETRRGRR- Capow ------VRYTSPGPLVVSLRLARDRDARPKHVVAAENGRMLYNSSSKYLVGVFDRKKHTLDVYDLKPTVKRMRKKQEAEQKKNDLVEAFGGRKKKNELLTNIK-NKIEIQSTLDTAAKDDLTLNEVMDQADE-HRP--IPAFNADALSPDEVYPLENLI--TPEEYKVLAKVLEKAAEEIQAMRAAPLILNWVRDLPQKEERRRQARILLYINYLLNFNSTEPPEDVLKHLKAKFAEGQPIFAVPTFLKDKLLSYVFVLCLMLLTTML-KMKPDRATEHFRALGCRISREEMGDEDTSASATGSVK-LAVLGVPLQFPRRGR-RSK Catan2 -MKRKF-----IGPVLADQSFSHAHFKSSLRVVTGDSPTIQLYGDSTYAVGIIDKVRGKVRVVALEPKYKLVA--DKSSAARNALGTTFGNKRAKTAIKALER-GRINLHASVEHSLEFVPTSEELALELEL-DNP--LPPHDLQATDVTQVYPLDGLF--PQRAQGALVAKVRSAKDLLEQL-GGIWLEREIVSLLVPKQDQSRAALCLYALYLVRMSALVAPDVLAWDLLNGYTDTKVKHALTPRAKTRLLCHVLACYLHLVAKDL-GANISQVQELLRAMGCNGTSAAEKAEGLSAFDK-STT-RYSLSAPLKLPGRIAKKGG Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 DKKRKRVRVDMLGPLLAKLSFA-----TELLFQSSDHPRLDYIAQ-QDYVGVYDPATSKLQIVPVRSTLRSE---RQEQAKRAALAAEFGSKKSRKALEDRTL-NAIKVLKQMSSSTSVMPTSQDLAAAVDS-SKP--RPIPNLAAEYPGDVYPISTVV--GSELMTMLVKDWVQAAAGQGVE--SKYVARRIVKLA-NKQ-IQKLKVLRFILLCINFGKLEAPAGCVLAIRRKFAP----SEMPRWNVDNLMTHIAAAALIVLREDL-KLENKEIKQYFAELGCKLTTQTDLTNKL--TKASINHFVAKLKLPLTFPKGGRFRSK Coere1 GSKRKSVKVAIIQPVLAASTFSVDKEHSNRCIVVSETEKIEYVGQNKYLVGVYDKAAGTVTFRKVNPVVKSLK--ISSREARNELGEEFGSKKRKSQLRAEER-NKINIEASIELRSSSMPTAQVLKAQEDT-SRP--VPKYNPTATVVSEIYDMEDLL--PKAVSGHIVTAFVKAKEYRKLL-PSMFVEKKIQLLLEEKPDVVQLRRLIYLSYLLRFEGCLEPE-VAQAIFERFAEGTPVYTKTPAAESRLICHICVLMLSVLAADL-SIPNKKAESYLASVGCKLETAGEISATVSKRVRNAGK-KALLKAPIKFPKSKY-RK- Conco1 ------VTVDNSGPYLTNVQYE-KERSNQQRILYGENDKMEYTLSNQYLVGIYDPSTKTVTFQPMNRQVKVLKNDAAAKDQVEALGQEFGTKKKRSEIAMKKK-NEVDISSAIKAEA----NPDSMDPLLGH-KQT--LPPFNLSAKNPEDIYNLKQFF--NNQVLNTLIGKLLNCKELDNLM-TSKFLHLHMSEYLGGPKNKDAIKKLQLIGLLMKLSKLKTCSNVGELLMEQFTESKANVMIPDNLKRKLACHIIIMILTLLANDL-KMDLNQATQLAYLVGCK---------GPQKGQPQVSK-VFKLVAPLHLQTNKK-KRK Conpu1 AKKRKRLTLSSVGPVLATTSFK----TEMPTLIAGETDAVEFFSSDRYYVAVHRKSTGTTTLRPLTQRVKALK--SALQEARAALGETFGTKKAQAAIRAQER-NKVDLQDSIAANTQSLPTQEEAKASADS-ARL--VPKYNADALTPQDIYPLHNII--PEAEWKSIVSSMTAASERTSLL-PSNWINQHLNQAFAPSPNKTVLRTLFYISTLLAFSAIQEPSIIIDGIISRFTEDATKLQSTTRSETLLLAHTFALCLRVIASDL-QKPVTTINQLFKSLGCTINTQSDLKRGLPDSAA-ETK-RAVLSAPLEFPKR-M-KRR Copci SKKRKRFELSSGGPFLVKTAFN---DAQNDILLAGETETVEFMTNEHYFIALHNKKTGKVAVLPLVHTVKALKP-SKTQEAKNALGETFGTKKAKAAIRAQER-NHVDVMDSIDKGAEGLMTTEEAKVASDT-NRL--IPPFSTEATSPDDIYPLYSII--PEAEWKALISALDSTKERLALL-PSEWLRQHLRNSGTPKTRKRNLKILLYISAMLAFDQIYEPSIVADSLLSRFTEGSTSYQSTSTTKTNLLTHIFALCLKVLAQDL-SMKTAEVNQLFRSLGCKMVGDRERTRGLSDESA-EKK-RAVLTAPVEFPKRLR-RKT Croqu1 KRQRARVKLSDVGPALVTTPFVRKADEKAKQILAGETDQMEFESSRTYLMGIHSSAANTLTLFPMRSTVKQLKA-EDSQNSRTALGTTFGTKKVRRAIQAAAR-NTIDLTEAITNSSMALPSAAQQTADADA-VRP--IPPFNRNATSPKEIYKTSDVV--SSVELNSILANITGCQQAIRLL-PSLYINQRIESCWSNKKEEKRLRILIYISYLLKLDHLKRPDAIIDGILQRFTEGSDQRIMTTFTTRKLLCYIAVLCLMHLAEDL-QEDTKVVHEIFRTLGCTIEPANEIAVKYGTDVKEKER-VARLVVPLVFPERRK-RQK CryneH991 -QKRKSVSVSDSGPAFVKIPFTRDAATKQHTLIAGETEDVEFFSTNQYLPAVYDPSTRTVHVHPVAHRAKRLRA-AKAQTQRNDLGETFGTRKAKAQIKSEEK-NRVDLMESIGE-------LEEENDSVAP-SDF--IPTPNIDTADPTEVYTRESLI--TAQEWAAIASRLLAIKERASAL-PSPWLQYKSRAVANKTSRKTQMKYLYYLSCLLTLHKLAPPRQIIDGMLSRFAEGLKH-NVTEKTKTKLLVWICLLYLILVAKEL-KMEPAKVATLYKQLGCNVKSPAEREAGITLAQANAAR-RAVLVAPVRFPKKRRGPAK Crypa2 ------IKVSSSPPVVADAVFNRPAKRDDLLLHSASHRTLDYTAR-KHYIGLLDPTTGQLQLAEVRGAVRAQQ--MQPQDQRTELGQAFGTKKAKKALAAVVE-NAINLMASMKDVAMSVPTHEDLQSAIDA-GKP--VPRGNLEADEIQDVYKPEELI--GRDVLELIVNDWMQAKKNEDVK--SRFVANRLRRIG-GENAVARLRLLRYTYFLLVVDKLQEQPPVIESIRRKFTE-----VMRKPHVDLLTTHLCAFACILLKEDL-KLEQKEMNQFFMEIGARIN-KRKVEE-------GRTDCFGVLKLPLVFPKRRGRR-- Debha1 GEKRKRLRVSSPAVVVGDMEFDHKK--NDEFVIHGENERLDYNGETDYVVALYDPLNKSVDLYKTAKSKRSFKQ-AGVRTQRNALGEAFGTKKAKAAITNLEK-NRIDIVDSVKETTQDLPTRKQMEDTVTH-DRP--TPIANVEATNVEDIYELYNII--PKREWSYLVNSLFTEKQRLELL-PSIYVSKHLAPLISNNTEKLQL--LYYASLLFGVQTLMLSEILVDGILERFTIKDRSFVIDPHHEDKLLCYLLAIIFHILAHEL-NMKPTRLVSLCKALGAIIKTVAQAEAGIPKVSASTYK-VATLKVPFKLPESKRVRKG Dekbr2 AEDKSKIPVSVENTILTSTQFHHKKRKLNDVVLHGENENLIYDGSLKYCIGIYDPESRSLKLVKESKKLLNVKM-TDVSEQRSRLGEEFGTRRAKAALSSYKK-NRVDIASDIQKSTSNIPDKVKLTKTVEAENRL--IPKYNEKAASVDEVYPVEGVI--SEREQGMIVDVFLQQKTLLELM-PSVYLLDKLEKQDASSDSKLRLKIMYYISTLMGVDKLLESTFIVDSCLKRFTD--KHFYMDPMNEDKILTYILTLMLRLLAQEL-SINPSRLVSLLRSLGCHTKTIAQKEANVPKNAV--YK-VAVLTVPLKLPPIRRGRKA Dicdi ------VNVIENKPCVLEPEFI-----KRHRVVLTNTDQLEYESEDKYAIGIFDKNTKQLKIVPMNQSVIGYT--SREEDKIKKLADSFGSKITKKKMQKMEM-ENVEL------------------ADIESNEKPFDLPDFDAETNDVRKIYNIEAIL--PPRIFFGLFLDIISK--------PPEYFKDQLKRFEDEEKVVYNCKLLTFMWYSMILEPLIKTSEVINFLVSIFGSNHKKYNISQDDKLKIYNYLAIFALKLLAQSL-SLTSSSFEKHFTRVGCKVV--------------GSEKRSVRLEAPLKLPKRFSN--- Dmel ------IIIESNIPTILDADFS---------TVDGKKHALVYAGDQDTYIFIRNKLTNKVKVVPYNHVYKKLE------HANKKLLKEFGGRKASRFVDNREQ-MMVNVNSSMLNEDEEDGTLGDVSEYLAS-----IVPEFNKEATKVDEVYAVESLI--PSSLLERLAKVVFST--------PSEYLKSCLAKIQESKRDFLHIKLIIYMDALQSLRQMQKTEKIENDIRHRFADVAKKGTRTNFSSEKALTHFIVMALLLLSRAL-ATTKARIKQYAHIVN-----------ALPKSNS-----ILSLRLPSKVPARRFQRKK Enthi -RKRHLIKVESEKPCVIELSFS---------IRGSMGETLQYKQIEKYGIGIRKKGSTTIEIIPLRHEISDAET-----EQRLDLNNSFGT--SRHAINKVLR-GRME------EREEVVPGEKEEKDVLDPKDFP-DIPPFDPVTTEASEIFALDTLM--TPDEKTYYVRNKLKANEVMNII--TKFGASFVPLLSQ----MEKVRLLTVVSLLELYENIARDETVFVGLCDRFLDESKKYIYSNLNKMLITNTAIVTALHIIGVDF-LMVDIVTKRHLIRIGCIKE-------GVRREE------CYTLKAPIKIVSKRASQKK Falba AQKRRR-----SSPLLVASQLESFNQTKPRRYLASDVGRVQFEASNRYAIGIFDKASGTVQVVEASMKIHALDT-SGKDDRRNDLGETFGARKLVSQIRTQER-NKVNLDARVGAMAADLPDPDAPEAAVSE-DSP--LPPFDRLAATPEDVYRLDVLI--PPAEEAGIIALLRDASEIERVVKECNFVARHLRIQHAVTASQPVLRMLAYMTALVRLNKLTYTADGAARCVSKFANAIKGRVLSSFARDLLVSYILALCLHLIAPDL-LLDRKKIATYLRNMGCTTSRTRTFSDDLTATNSKPTANVYVLRVPLTFPRSRG-RAA Fomme1 SKKRKRISVFDVGPILASAAFANKNAGRRPLLVAGETDAIEFHSTGRYLIGIHNKRTNTLLLRPLGRRVKALKT-SSTEEQRNTLGEMFGTRKAQKAIRTAER-NRVDIQESVESGTRGLPSQEEAKELADS-TRQ--IPKFNLHATKPEDVYKLYDIV--PESELNALIKEIMNAEERMKFV-PSDWVRQHVAAIFETKTSKRSLRIILYIACLLVFEDLEEPSNVIDGIYSRFTEGSSRVQFTSDNAVRLLTHIFALCLHVIAADL-REPVTKINQHFKLLGCKIESTVEMSRGLSASGA-EHK-RAVLRVPLEFPKRMK-RRN Fusgr1 SEKRKR-TVSSCPPVIANIPFHKDAAKKDFLLHSNAHRTMDYTVK-NHFLGIYDPKTGKLEVVEMRAAVRAKQ--AGERQLKTDLGQTFGTKKAKKAIQENVL-NAIAMLSSVGEVTSTMASREELQAVVDE-ARP--VPIPNLEATEIQDVYDPKRII--GADILKLVVREWQEKQHKESIQ--SRFVAARVTRVA-NEDATDRLRVLRYFFFVLLFDKLREPEAVVESIRRKFSE-----EMRKFHIDLLITHCCVFASIILRDDL-KIDQKTMNSYFHEIGGRVKVTNKETK--------TTVSLARLALPLNFPKRHIAPKR Galma1 SNKRKRFELAEVGPLLVSTHFKEKNST-QDLLVVGEAKSVEFVSNERYLLAVRNTRTGTISILPLTHVVKALKP-SKVQEAKTALGETFGTKKQKASIRAQER-NRIDVMDSIEKGAEGLLTAEENKEAADN-ARL--IPPFSVTAEDPAEVYPLHDII--PEAEWKALVSAFDAAREKIALL-ASTWINDHL-KASTGKSKKKNFKILLYISAMMAFEKLYEPGIVTDSLLSRFTEGSSSYQITSATKTRLLTHIFALCLKLIAHDL-SMAVTEVNQLFKSLGCKITGERERARGLSDSSA-DEK-RAVLNAPVEFPKRLR-KK- Ganpr1 -------MIKSTGPHLASSHFSSQRASRRRLQIAGEGGRVAFTGTQRYVVGLYDSHSNSLTLKE---DVRMIAVDSESQIARTQLGETFGSRKRQQALRAYAR-NQVDLNDQVQ--SNPESSSDDMA------SSV--LPSCDQSATTVEQIYALDSIH--PPAEVQQIVLKFLRDEDPQRLC---------------TSRSKDRLKRLIHTHYMLKMGKMRAPLVVFEGLTGRFMQVTNAYSMPPKLQDKLCCYILAALLHLVSTSM-KLPSKKLSELSSAMGLRLKVAWDSDSNVFSNEATLGRVRAVVYLSTV---------- Gloin1 GEKRK-VILENQTPFIGELLYH-----NGHINIVGENEAVSLESTVEYLIAIYDKHSNTVTFRDITPVLKRLR--ESELTAKTALNKEFGSKKARLKIVTRER-GEIDVDEKVK--TRAIEGQEVMKEE----SGI--IPTYDAITTDPSKIYKLEDIV--TPAEYDAIIQDLLKAKDRLTLL-PSNYVKSRLIPSLTRKVNHRRIKMLMYINYMMAFKLMAEPNIILDKLYERFVDGNENFKFTLKNDQKLICYMLVLCLKLISEDL-GITTTKLNVLFKGIGCSIRSKKEMTEGITKEYG--AK-RAVLTAPLKLPEKRGSRKK Hisca1 EKKRKRVKVQFLVPIIA----------SEFLLQSSAHPRIDFIGK-NHYVAVYDSDARTLELMEVRSCVRRVP--DEGSAKRTALTEAFGTKQSRKAIISVAE-NALLLLSSIPTASGGSPQKTA-QAEIQA-AKP--LPQPNLAATHPSQVYAIETLVPNGLSTLRTMVKEWQTSAAGEPVL--SRFVAHRVDHVV-SGD-ATQLQLLRYIMVLIQLEDLRRPDSFLEALRRKFVP----YFLSKTDVTFLHTTICALSLHILRDDL-GLEFHTIQQYFRELGCKVGRESEFAKGVR-SKVAGARRIAKLRVPVEFPKQRGG--- Klula1 GSKR--VGVSAPSVAVSDTTFENKKN-SDKYVLHGENDRLEYEGQTQYVVGVYDAATKSVELYKLSKSRKNLMQ-ANVRLMRNALGEAFGTKKAKKAIADMER-NRIDIVDTVKTASKELPSKEELQETVSS-DRP--TPLADLDATDVEQIYPLYNII--PKKEWSFIVGSIMKEEKRLEYF-PFQYVANKLPTLTQAQMQKLQL--LYYLSLLAGVTKLLEPDALLNGILERFTIKDKSFFIDPQREDKLLCYILVIIMHLLAQQL-NLKPSKLVSLFKILGATVKTVAQAEAGIPKSSASTYK-IATLKVPFKLPEIRRGKGP Lacbi2 SKKRKRFRLSTVGPLLVSTVFK-ENDTSQDLLAVGETDSVEFVTNDHYLVAAHNRRTGSLSILPLTRTVKALKP-SKTQEARAALGETFGTKKAKAAIKAQER-NVVDVMDSIDKGAGGLMSTEEAKDAADQ-NRL--IPPFNATTTDPSDVYPLHDII--SEAEWKALVTAFDDAKERIALL-PSKWLTGHL-SIISGKSKKKHMKILLYISAMLGFDQLYEPSIVLDSLVSRFTEGSTKHQATSTTKTLILTNIFALCLKLLAHDL-SMKASEVNQLFKSLGCKITGERERTRGIPDSSA-STK-RAVLNAPVVFPKRIK-RKT Lenti61 GKKRKRLQLSTVGPVLATTPFQ-----TQPTVLAGEAETVEFFSADSYMIGVHDKRSNTTTLRPLARQVKALK--STEEALRNNLGEAFGTKKAKAAIRARER-NKVDLQDTIMQNTDTLPTTEEAKATADS-SRL--IPPYNADAHRPQDVYALHDII--PEAEFNALIGAIKSAPDRFKLL-PSDWVKLQLRLIFSGKPDKTELKTVYYISTMMAFDALQQPPIVLDGLISRFTEDTNKPKITPQMETMLLTHMFVLCLRIIAHDL-SMPPAKVNGLFKSLGCVVKSFAELKEGLPDSAG-ATK-RAVLKVPLEFPKRVK-RAR Malgl1 -----------------HANFQAPSDADDRLLLAGDTNAIQYTSTNDYLMGIYDKTKKQVTLRALNRSIKALA--ATERRARRDLGEAFGNKKQKQAARNMDR-MKVNVASGIGESASTLPTEKELTASLNT-SRA--LPQAHLDATEPAGVYPLESLV--PMTVLNALTRHLLKCAELGKALRVP-WLLPRLWQIVQ--RAMELIRIGYYVAILLAFSSISQRDIVMEHLVSHFAEGSQRYAMTATGDTRLFASILVVGLHL-------APEAPAQELSVT----------------------TQ-RFVDT-------------- Mellp23 KKSKRSVKLSGLGSALVKTPFNHKVDPKATKILAGETDQLEFESNRNYLIGLHSIQDQTLTLFPLRPTVKQLKK-EDEEASRNMLGTTFGSKKARRAIQAAAR-DTIDLKEAITTSSITLTNSIQEANRIES-EKP--IPPYNINATSPKEVYKLSDVV--TNLELNSIIAHITYCEQAIRNL-PSNFINKRIESCWNNKQEEQRLRILVYISYLIKFDKLKEPDSILDGLLERFTEGTQEFLMTTFSNRKLLSYICTLCLIHLADDL-KEDKKSLTEIFRSLGCKIDSSGELTVKLGKDTKDKQR-LARLSVPLVFPERKK-RQR Mnele -KTKKLVTMRTKEPIICKTEFTNTSDMAAQRMVIMDCDGIQSVGKSQYMVGVLDKETNEMTLRPLKPYVKSFE--MEKEEKYKELAMKFGANRIQKTLRGKDRVKEMEAVASVD--TSNLTEQADLH------NDI--LPPINTEAKSLDDVFLITDLI--TEAEIAALFTTVLRAREQEKY--P--FMLSRLPVVIEDHLAHLYLSELLYISYLVTLKSLGNPSVVIDNMYKKFTSGKLRTSMSDKQRNKLIAHILALTLLVLCRDT-GVKSRVLSDTYRSMGCSINKGQDKGQ------------VAVLKLPVKLPPRKGGKKR Monbr -GYREPLEVNNMGYLPVQALYDHPEAAPRALLADIRGEQTEFVNPARAVVEVMNAETGYASVPKEGSTARTASKDSESEQARADLTETFGGKKKKAQLHALER-NKFVMYEALSMDIDSDPAKQDQ----DR-FRP--VPQYDPAATVPADVYPLKHLI--SHADASAVCKPFTAAQTVAKWK-ASPLVFDGLD--LLGSAKKMLARVLQYLVELLKFEELQSPPAIIDSFMDKFVFA----NLSKRNMHLLIHHLLVLAFHAVAEAL-SMAPATAVTHLKAIGCKCS-------ATPQTAA-----VAELVAPLQFPKKRGPPKA Morel2 --KRKNLEYAKEGPFLADVPFN-KPDSKKRRIVEADTGKVEFVGQNRYVLAIRNKETDKITFKDVNRTIKTLKA-NREQQAKNILGHTFGTKKIKQQINSVAR-NAVNLHDSIAAKTNALPSKESIKARADE-DRP--IPPFDLAATKVEDIYKIDSLI--APSEYQVIFKALLE-QPLAAL--PSSYVNGALTAALSSKKDRHRIRLLMYISILMAFETVSRPSVILENLYERFTEDKKRHTFTPKSKDKLLCWILAIALTLLTRDL-SMKQTRVNELYKSLGCKVNTATEKA-G-ASNEEKTMK-RAILTVPLTFPLKRGPKAK Mucci2 ------------------MSFT-NGDVAHQRIVSGETDKVSFKASNKYIVGVYSKKNNTLNIANMSRTVKALST-IARGIARAALGLAFGTAKAKSQLKSDER-NLVTLHSEIGKATANIPKKSEMKKSMEL-SLP--VPDHNMDAESPDDVYDISSIV--TDEELQTLYKELLKEEGVKNLL-ASKFVNDRLMSILGGKKDRKRVRTLMYINLLMAYRKVEASPLVLDKLADRYTE------RTPMMADKILLYMFTLILSIIGKDL-LLKPSKVASLFRSLGCKVDSAEECREGNK-----QAK-KATLVVPLKFPERTGVSRR Mydma -----------ARPILVDIKFQSKNPKSNKRMLIADTKALGYIGTIKYYVGVVNKKTKTIESVELKPYLSDKR------EKVDSLLATFGSAKQKSLFKSRKKHEAVKIVKDIPSPEKSEPVQDFFV-----------IPPKYDDATRVEELFHIDDII--DYKHYQHLSKPILECQEILEKW-QNDFVLHHISMLPTRLEREERSCYLLYLHFLMVLKDIRKPLEVKRYMLDMFTADGRYRTIPTKYKDKLLCYILVLSLIILLKDL-KLTVPKLTQLLRAIGCTVRTPAEKNEGITTD-------VPKLIAYLTLPKELQSKKT Neucr2 DKKRKSINVGAAPPVVASIQFQTPADKQELLLHSANHRTMDYTAR-KHYIGIFNPKTAEVEIVELRGTVRSQK--MEEKAMRNELGEAFGTKKAKKAIRDVTE-NAITMMDAIKTATKDMSTKEDLQAAVDN-ARP--VPRGNFNADEIADVYVPSQII--GSEVLNAIVMDWQESKNLEDIQ--SRFVAKRVSNVA-SDDAVHRLRVLRYLLFVIIFDKLREPEIVIENIRRKFSD-----VMRKTHVDLLMTHCCAFAAIILREDL-KLEQKQLNQYFIEIGARVK-QQKVAD--------KMENFAVLQLPLQFPKRLPARKR Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 DQKRKRLAASVLAPVIASLRWNKSRANSEMLLQSSDHAKMDFVGR-KHYVAVIDPEHKTWKVVELRGAVR-----SEEEAQRTALTNTFGTKQSRKAVQSMAE-NAQLLISSLPTASGHA-KALAMQAEVQA-AKP--LPTPNLAVSHPSDVYTIETLVPGSHSTLSQLVDEWKSQEAGLGVT--SRYVSNRVGAVV-SDN-QTHLQVLRFIQLLIEFEDLRRPESVIDAVRRRFAP----GYVSKNDFTLLHTTICALSLHILRDDL-RLDPNTIHQYFRELGCRIDRETEFAKNIKGGRAAHARRVARLRVPVEFPKSRGGRK- Phybl2 -----------------------------------------------YIVGVYSKKDNSLTVTPMTRTVKALST-ASNAAARAALGLAFGTSKAQQDLRNEER-NKVEMHNEISKATKNTPTQASLRKEMAK-DLP--IPPHDINAESPEKVYDMEAIV--SEEELNATIKDLLKEEAIQTLL-PSDFVNNRLLSILKGKKDRKKLRTLVYISYLMAYSKLEVPSLLIDKMTERYTI------RTPLMADKILCYMFVLCLAVISKDL-SIKPSKTTTLLRNLGCKIENAEDLKNDTKL---ASAK-KAVLVVPLTFPERKFARK- Picst3 GVKRPRIRIASPSAVVGLTEFDHKK--SDKYVVHGETETLDYNGESDYFVALYDPLNKSVDLYKTARTKRVFKQ-AGVRTQRNALGEAFGTKKAKAAITNLEK-NRIDIVDNVKLSTQDLPTREKMAESVTN-DRP--TPLANVDATNVEDIYPLVNII--PKKDWTFLIGPFLSEKKRIELL-PSNYINKHLTLLVAKNSEKLQV--LIYASLLFGVQSLMTSEVLVDGILEKFAIKDRSFVIDPHHEDMLLCYLLALILHILANEL-NMKPTRLTGLFKALGAVIKTVGQAEAGIPKAAASTYK-IASLKVPFKLPETRRGKRG Plicr1 SKKRKRFQLSNLGPVLVKTPFK----TAQTTFVAGEADTVEFVSSSRYMVAVHNKRTNTTVLRPLSRQVKALK--SALEQARSMLGETFGTKKAKANIRAAER-NKVDIQASIEKNTVALPSKEEAKAIGDN-ARL--IPAHNATADDPADVYPLHNII--PEVEWKALISTFTSAKDRLALL-PSKWVAHHLERIFATPISKQHIKILFYISSMLAFDPIHEPSLVVDGLLARFTEGSTDALTTPQTETNLLTHIFALMLRLVADDL-SMTPTKINQLFKSLGCKIEKMTDLKRGLPESAA-ATK-RAILKAPPEFPKKVL-NRR Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ------VALAMVGPALVTTQFQHRSNEKSPALLLGQTNELEFRSENSYMLGLHVASAGRLTLFPLRPVVKRLRA-TDNYEARRTLGTTFGTKKARRALQAAAR-NKVDISAAIAENSSCLPSATVQAQEVDA-NRP--IPPYNINAANPKDVYLLSDVV--TNLELNSIMGPILNAEDAARCL-PSQFVNSRLNALWKDKKETKRLRILIYISYLIAIDSISNPDSIIDGILNRFTEGSLKHNLTSFSKIKLYSYIAVLCLIHLSDDL-QEPTKSINDIFLNLGCKMSTVPEFEAA-SKDAKNAQRTIAKLVVPLVFPPKIR-KRK Punst1 SKKRKRVKLSSVGPVVAKTSFK--EATRRDMLVAGEADSVEYASIDRYYVAVHDKRTHTVTIRPMQRTVKALK--GAAEAARNALQNTFGTKKAVTRMRAQER-NRVDLQSTVEKNTEALPTKDEAQELADA-SRL--IPPYDATATTPSEIYKLYAIV--PQSELDSIAAPFLSAQERTALL-ASSWVNQHLSALFRKGIDKRILKVIVYISAMIAFQKLQEPGPVLDGFLSRFAEGSTKYQVTSQKRALLLAYMFALCLHVIANDL-AQPTTKINPIFKSLGCSVKGLTELKRGLPDSAA-ATK-RAVLDVPLKFPARLR-RRT Rhior3 MGKRKHIVVAEEPPYLVDLTFT-REDAASQRHVFGETDKVCFTGSNKYIVGVYSKKENTLNITNLSRSVKALQN-AARGAARAALGQAFGTAKAKKQLNSDER-NLVTLHAEIGKATVNVPKKQEMMKSMAN-ALP--IPSHNLDAESPEEAYDLSSIV--TDEELNSLPKELLKEDGVKSHL-ASKFINDRLMAIIAGKKDRKRVRTLMYINILMAYRKVEASSAILDGLAERYTE------RTPVMSDKILLYMFTLILSVLGKDL-LLKPVKMTSLFRTLGCKVDTVEECREKMK-----SAK-KATLVTPLKFPERTGGPRR Rhoto1 ARKRQKVQLAAPQPALAKTPYT--KSGRQQAVLAAETDDVEFESRNQYMLGVRNPRTNILTLHAFTPTVKSLKS-AAQLAQRAALGSTFGTKKAIKQLRAQER-NKLNLTLSIQAAAGNLPSMQTIEDEANE-KRP--IPPYNKDAKSPGEVYDMDAVV--SQAELNAVLGDLISAKARRDML-PSDFISTKMRQLLPSKRDRGRLRLVVHLSHLFQFTKLVESNAVVDALLERYTEGEDARKVTTTMELKLLT---------------------VGELFRSLGCQLISAADREKGRASSAAAKSK-KATLKVPLQFPKRKG-Q-- Rozal11 IKPRKLIKVEDDPPYVVSLEFQ-----GRQRYVEAVTDHVKYKGHNRYAIGVIDKEKNEIVVKSTSHSLKLEKV-QQLSDARNDLGETFGNKKRKKDIKTIQR-SVIDITSAIEESTLVLPETQELEEMMDE-SRP--IPPYHKDAENIEDVYLLDDVI--VDVA----ISPLLNAEEIDEVL-SPEYVKERLRPALSSIKDEETIRALVLLSYFIRLPHILQTYKMAEQMLELFTEGKKKHKLTSALKDKLTCYIAVVSMIALAQEL-ATPGSKLAECFKTAGFYI----ERKRGKRETDR-----IAKFKVPLTFPKRRGAAK- Sacce1 SVKR--IEIESPSVAVGDTTFDKKKSEKDEFVLHGENERLEYEGYTQYVVGLFNPEKKSIQLYKVSKSSKNLRSKSDTRALRNALGEAFGTKKAKKAIADLER-NRIDIVDSVRTASKDLPTRAQLDE-ITSNDRP--TPLANIDATDVEQIYPIESII--PKKELQFIVSSILKEEKKLELF-PSKYVAKKLDSLTQSQMTKLQL--LYYLSLLLGVTKLLEPEILVDGILSRFTVKDRSYFIDPQNEDKILCYILAIIMHLLAHEL-NLKPSKVVSLFRVLGAIVKTVAQAEAGIPKSTAASYK-IATMKVPFKLPETRRGRGP Salro ------VKVDTSTPLLQQLLFTKSSSSNEPLEVRAHADAIDYVSM-NYMVGVRKAGTNELQLIPMTPRLSTEA--TPEKQARAHLVESFGGKKQKRVLHSRTR-YMLSMADAVTSSSSSSSSADGDDVEGGK-GRM--LPPNNLKSKDAAGVYPLDGLV--LSNERAAL-------KPKEEELTAMPFVIDVLERDIMGKQREARILALKYLAELLKFSDLVKPDAVIDGFINKFLISSPKLFLSKQKQHLLLMYILTIALHAFATEL-KTPLKEVENVARALGCIVKTSVDFEDGNPSKRA-KTNTLISLKLPLVF--TRRGRAK Schco3 TKKRKRINISQIGPTLASTPFR---DD---LFIGGETDKVEFTTNMRYLVAIHNPRTSSLTVYPLSHTVKALKP-TARAEARNNLGETFGTKKAKAAIRAQER-NKVDVMEGIDKGAENLLTKEEAKEAADA-NRL--VPPYDAATDDPMDVYPLHGVI--PEPEWKALVSAFEQAAERRALL-PSEWLQHHLRRAFESKARRRVLKIVFYVSAMMAFEELHTPAVVVDGLAARFTEGDPKLQATSAMQTKLLTHMFALCLRVLATDL-QMAQAQVNGLFKTMGCKIGTERDRARGVAD----DKK-RAVLSAPVEFPKKTR-KAG Schpo1 GKKRKYVKILPLPPLVTNTRFQKSNQSNRDASLIGRTERVQFEAKNNYCLAVADKTGRVKKIVPFERNILALQT-VSGTEQRANLGLAFGTRKSQKAIMEESA-NRVKLVSNVQKATEALPTQEDIAAAQAQ-DRP--IPPVNVGAESIEDAYKLEDII--PKEEFSAIIKPLLENRNWAKLL-PSLFINERFQRLLSEEVDQKRARILYYISLLQAFETLRKPEILIDGLIKRFTQGIGSVQVSSREVDKIICYILVLCLIVLANDL-NVKTMKANELFRTVGCRIMTETQRMAGLNKTDAKNHK-RAVLKIPLEFPKRRG-RAR Sorma DKKRKSINVGAAPPVVASIQFQTPADKQELLLHSANHRTMDYTAR-KHYIGIFNPKTAEVEIVELRGTVRSQK--MEEKAMRNELGEAFGTKKAKKAIRDVTE-NAITMMDAIKTATKDMSTKEDLQAAVDN-ARP--VPRGNFDAKDIADVYVPAQII--GSEVLNAIVMDWQESKNLEDIQ--SRFVAKRVSNVA-SDDAVHRLRVLRYLLFVIIFDKLREPEIVIENIRRKFSD-----VMRKTHVDLLMTHCCAFAEIILREDL-KLEQKQLNQYFIEIGARVK-QQKVAD--------KMENFAVLQLPLQFPKRLPARKR Sphar YSMRIP-----------AATFNHKHA-GRREVIVGSSENVEF----KFAVGVVNPDTGIIKI---GQIPKSLKKDAE--AAKTTLVESYGGRKNLRKMQARQR-NQLTAKAAL-FD---QFTKEDTQVLLDA-NLP--LPPVNAEATKQEEIYQYDSLI--TPQEYRALSEELLSSQDMSK----CWYSKFALSQAMRGPWRVKMARTIIYIQYLMNIWHLVDPMTIRDRITDTFT-AKKKYTLSSFQHDRLAAHICALSLHLLAKDL-RLTLPRIKSLLKTIGCGLN-------GT-----------AQLTYPLKLPKN------ Spipu1 -KKRKVPATFDDTPLLVSVKFQ-RGENKKRRIVVGQTSKLEYVGDNRYVIGVFDKNTKQLTLREMATTVKTLKA---EKLARNALGEAFGTKKRRQAIRALEK-NVVDIKGAIDEKAATLPSREEIRQEAQL-DRC--IPPYNLQAQSPADVYNVEDII--TPAELQAIFKQIWRASDVKELLEPTSWVWDKIHVCLQ-KDDSVRMRRLIYLAYLMKFQAVGKPQIVAERLMNEFTEGRRRYRMSPKLQDKLRAYILTLCLILIARDL-GIAVNKMNDIAKELGCKHQ----------KNAEKSTK-RMALTVPLVFPQTR----- Sporo1 -RKRQKVAVASPAPALAKTPYS--RD--SHSVLAAETDDIEFESRNEYLLGVHNPRNNTLTLHSFTPSIKSLKD-HQSLAQRALLGSTFGTKKAIRALNAQQR-NKLNLQASIQISSASLPTAESVEQVANL-ARP--IPPPNFSAQKPSEVYSLDDII--SPSELNSILSPFLSAKERLALL-PPDFVWTKFKQILPSKKDRERLKLVIHIAYLFQFSKLVEAPAIVDALIERYTEGGEQRKVTSFMELKLLSYMLVLVLKVIAADL-GMGSKKVQELFRSIGCQLVSAADREKGQAESVAAKLK-KASLKVPLEFPKRKG-KAK Stehi1 TKKRKRLEPSSVGPVLVETSFK--HEGRQNITLAGETDSVEFEGANRYYIALHRPSSSKVTLQPLGHTVKRLKP-SQSEMARNALGQAFGTKKALAQIRANER-NKVDLQSGIERGTENLPTMEEAKSAADM-ARL--IPRYDAEATSPEEAYPLHGII--PEQEWSALIKTIKAKPEWNKMW-PSTWVKQHVNKAFGPAQQKRVVKLLFYIAAMMSFEVLLDPETIVDGLLERFTEAATTRQATSSTQTNLLSHMLALCLKVIAADL-QMAANTVNSIFRSLGCKIEDAADLTKGIAPSAV-GEK-RAILKTPLVFPKRNN-KRR Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------LSVTYHAPIVATVSFS-----GRNGSLECKMDGYTYAGTTEYYVGVVG-SDESMTLYKVMQMLDAAKK-AQDHAGRDRLVATFADQRNKSGLIKARQ-QVISLESALEAKALETASKSELDEQFLT-QKP--IPPFNMAATEPEDAYPLERIL--PMVDMQAVARPLVDEKSLSQGALPPSVIAESLTSLSAPSDKRRMAATLTMATVLIELELVNEPSVLVERILKEFLTPVTHSRRSQRDQHKAMAYVIVLLLHYLRLDL-GISIQRLLQHAKTLGCTIIKAGSGTKSADSEVAGPAY-SISLTVPLEFRDKKRGPGQ Treme1 KKKRKSVIVSPVGPVFVTIPFTRTPESKQPTLLAGETEDVEFFSVNSYLPAIYDPSTQQLHIHPLAHQVKRLKP---AEARRNDLGETFGTRKAKNQIKAQER-NKVDLMESIGEK------VMDEEGPVPP-SEL--IPIPNLETSDSSLVYPREVLI--PNNEWDSILSSFRSSIQRLQTL-PSTFIKNKIVSIMNSSKKNTMTKYIIYLSSLFAFTELQDSPQIISGLCIRFGEGGKRWKVTEMTKMKLLAWICTICLAVIASDL-KMTPNKVVDIFKSLGCKVEPPP----------GTNSR-KATLKAPVIFPKKRRGPVQ Trire2 NKKRKRATVSSCPPVVVDLVFNKNASSKRLLLHSTSHRSLDYTARENHFIGIYDPKTGKMEVVEVRGTVRSKQ--TSQQDQRTDLGQTFGTKKAKKAIQDKVL-NAITTLSSIGAVTSTMASREELQAVIDE-AKP--VPKANLDADEIYDVYRPEELI--GADILNLVIREWQEKKHGESIQ--SRYVVSRVQAIA-NESAEMRLRVLRYLSIVLLFDKLREPEAVIENIRRKFSD-----QLRKFHIDLLIAHCCALACIVLRDDL-RIDQRMMNQYFHEIGARVKVKDKAED--------RILHVAKLALPLDFPKRQIRARR Umbra1 MTKRKHIQVADSGPALVDTLFD-HRSSKKQRIIAGETQKIEFVGKNRYLVAVYDKKDNTVTLQEMHRTVKALKT-AQNSEAKNALGDTFGTKKARQQIKSMER-NEVKMQNEIDVAAQAVPTVDMIKEDQEN-QRP--VPPYDATATAPADIYNMDDIV--SAEELNAVIKDVLKCQELKEQL-PSEFVNTRVLSIINGKIDRKQVRVLVYISYLMAYDEINTPSAIVDRMLERYTT------RTPLMADKLVCYMMLLCLMALASDL-SLKPTKTVNLLKNVGCKVETASQAAEGIK----GKVR-RASLIAPVTFPVRKIPERK Ustma22 PKKSKKLKVNGSGAAFASTRFSA--DGDERLLLAGETDTMAYVGNNEYMVGIYDPSSSSVTLRAVTRSIKANS--SSTRAARRALGDAFGNRKQKANARNQDR-MKVDFTGGIQDNLASLPSLDEVLASSTS-SRP--MPPANLDAKHPAEAYRISDLI--PSDIFGSLIQKLIDNHEALKELLPPAWIWSRLLDNLQKEDAKDKVRIAYYMSLLWFISSL--KRII-KAILSTFTENSERAVMSAFHQTKVLAYMCALALHLLARNC-NIPPATLRELFRTLGCTSS--------------GGEK-RMVLKTPFTLPQRKG-KAG Walse1 -IKILS-----QGPALANTEFS-TNDS----LIAGSNDSIDYVSNDRYLIGLKRKNSDTITFQEMNRQIRSLAA-DMADRARNALGETFGTKKAKKAIKEAER-NQVDIQQDIAENTDILPTRENIKAEADA-QRP--LPPYDQSGGSLEEVYKISSLI--SDPEFNSCVDKLLTASAIAQLLPSVNYIIERLVALKTNKSSRTKVRLLLYMSYLFAFSKVQEPPVIVDGLFSKFTETKS--SMTPFTQAKLLNYILVLTLHVIAKEL-SMPVQKINESFKSLGCQLVNLAEREKGEESQDAKSAR-RATLKIPLEFPQRRG-KAK Zygro1 S-KR--VSIESPSIAVSETKFDRKAS-KDEFILHGENDRLEYEGRTQYVVAVYNPSKKSAQLYKVPKSTKNLAS-SDVQILRTSLGETFGTKKAKKAIADLER-NRIDIVDSVKTASKDLPTRTDLENSVTM-DRP--TPVANVDATDVEQIYPVENII--PKREWNFIVGSLVKEEKRLEML-PSQYLAKKLPSLTQTQTTKLQL--LYYLSLLLGVDKLLEPETLLDGILERFTVKNRSFFIDPQNEDKLLCYIMILILHLLAKEL-GIKPSKIVNLFRVIGAIVKTVAQAEAGIPKSSASTYK-IATLKVPFKLPQTRRGRAA [Cluster2518.fasta_al_trimmed; alignment length = 246] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 VRDHYKSDHKYNLKRKLVSLEEFDRLSPLIYFFGVHKCLFALFMMGGGHFAAAIVSFLEHKTFHRYTTRRKQGGSQSVMDNA-KGANSAGSTLRRYNEAALRN-DVQDLLKK--W--RPYLERCEHIFIRADRSVFFTDPRIRTFPFTTRRPTTNELRREITYLELLSFVRKTLLHYASNNGMVLILLCDPTLRTAWDLT-KRKDVKQAFQHIGVPLSREAANKERQE-ARERREQRARAAEARMG Aspfu1 QREHVRSDHRFNVKAQSLDEAQFAKASPLYWFLGVYRALFFMCMIGGGHFAAMLVSVIAHKSFHRYTTRRKQGGSQSASDAA-RGAHSAGSSLRRYNEAALEK-EIRELLRD--W--KEMIDSAQLLFIRANRKI-LFDPRIRGFPFSTRRATQDELMRELTRVQIQALIRRTPLHFAANLNVVSALLADPTIRTAFELA-GDRATRDAFRKVPAAVSKERAEREREA-KRRKRERRARAAEERIR Aurde31 QRAHFRSDHRYNVKARLVNEQEFAALSSVTWFIGVYNAVFTLLMTAGGHFAGVVVRVLRHKTFHRYTTRRKQGGSQSVNDNA-KGAKSAGAQLRRYGEQALRD-DIRGLLED--W--KDDIEKSELIWIRANRRI-FFDERLRTFPFPTRRPTQAELTRELTYVRALEMVQKTLLQAAARAAVVRWLLADPTIRTAYDVA-ASKTVRNVFRRVPSALSPERDDKKKDK-MRERRERRARAAEARLK Batde5 MRTHYKSDHKHNLHLKLISESQFLTSSPFVK-VSIYKQSLTLLMLGSGHFAGAVIDSIVQKTFHRYTTRRKQGGAQSSNDGS-KGAHSAGAGIRRYNEAALQT-EVRDLLIQ--W--KPHIKASQALFIRANRST-IYDPRVRSFPFTTMRPTQSEIMRELSTVKLSDFCKRSLLHIASENGVVELLLADPTIVRAYDVA-KDKPTRDAFRHIFEPLTAEQAEREREKEEKEQREKRALAAEARMK Botbo1 QRSHFRSDHRYNMKARLVAEAEFANLSPVVWFLGVYTALFALFMTAGGHFAGMIVQILKHKTFHRYTTRRKQGGSQSVNDNA-KGAKSAGAQLRRYGEQALRD-DIRGLMTE--W--SEEIASCERIFIRANRRI-FLDPRMRTFPFPTRRPTQAELTRELTRVRLLEMIRKTILQVASASGIVRWMLADPTVRTAYDLA-SSRGIRNVFRRVPSILTPDQDKKKGER-MKEKRERRARAAEARLK Botci1 QKSHVRSDHNYNLKQKIVTEIEFEKLAPMIWFLGIYRAIFFMCMIGGGHFAAMVVSVLAHKTFHRYTTRRKQGGAQSANDSA-KGAHSAGSSLRRYNEQALQD-EVRQLLTS--W--KGMIDTSELLFIRANRRT-LFDPRIRGFPFSTKRATQNELMRELTRVQLQSLIRRTPLHLAASLNLVEGLLANPTIKTAFELC-GERSTRDAFRNVPSGLSRVRDAREKKM-EEKRRERRARAAEERMK Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 DTEYYKSDYRYNLKRKLVTEQQFDKLSPFILFIGVYKAVFALFMIGGGHFAGAIISIVQSKTFHRYTTRRKQGGSQSASDNA-RGANSAGSSIRRYNEQALIQ-EVRELLHD--W--KNQLAECTAIYIRANRKV-LVDPRLRGFPFTTRRATTSELKRELTHLDLITLLKKTLLHYAAANGMVQVLLANPIVRTPAEVA--DTSARKVFQKVAPPKSKERTLHEQEL-TKP-REQRARAAEARMK Cangl GREHYQTDHVANIRRNLLNQAQFEELLPQILVYGIYKALFALFLVGGGHFAGAIVCFLEHKTFHRYTTRRKQGGSQSAMDNA-KGANSAGSTLRRYNEAALKT-DIQNLMEK--W--RPYLNKCESIYIRADKKI-FLDKRIKSFPFTTNRPTVTELKRELTYMQIVTLLKKTMLHYASQQGMVSILLCDPTIKTAWDIS-KNDTVRYCFQHVGVPLSKEQDEAETEL-TKERREQRARAAEARMQ Capow QREHFRSDHRLNAKRKILTIAAFEAMGPRVFFFSVY----CVLMCSSGHFAGIVFDIVAHKTFHRYTIRAKRGTAQSTMDSR-SGPKSGGASLRRYNEAALEQ-EIRELMAE--W--SLLLTECAYLIVHANRRI-FFDPRVRKVPFMTRRPTLKEAERQF--FALIDIVKETPLHVASANGTVTKLLADPTR-TPYIVA-SSKPVRDAFRSIPTALTEEQERKRLQR-RKAKRLQRLKAAEARLK Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin QTEHYKGEHRYNLKLRLIGEDEFGGMRPKLYLLSIYKKVLVVILLSAGHFAAAVFEVAAHKTFHRYIVRAKRGTVQSSNDAANRNAKSAGASLRRHNEQVLEE-NIKQLLLS--W--NEEIKNAALIFIRIYRKG-LFDSRIRTIPFVTRRPTFNEVQRELFSVQMFTACKTTLLHVAAKTGIIFTLLADPAIFLPYCLC-PNKEARNIFRQIPSPLSDVMKKKKSRK-LKERREKRLIAIERRMM CocheC53 QRSHVRSDHGYNLKQKIVSEAEFEKLPPLIWFLGIYRAIFFLCMIGGGHFAAMIVAVIAHKTFHRYTTRRKQGGSQSANDNA-KGAHSAGSSIRRYNETALVN-EVRELLNS--W--KSMIDTAELIFVRANRRT-LFDPRNRGFPFSTRRATQKELMRELTRVQIIPMIKRTPLHLAASLNIVIALLADPTLRTPFSLA-GDRATRDAFRGVPAAMTKTRDAQEKEA-DRRKRERRARAAEERLR Coere1 QRVHFKTKHQENMSRKIIVENEYPWNSRYLWFYGIQRRVLTILGSDGGFFAAAIFEIIVHKTIQRYTTRRKQGGLQSRQDNA-AGANSAGAQIRRHNERRLQE-EIYQLLEE--W--RPLIKTSTHVFVRVSRKT-FFDPRIRAVPVAMGRPTLTELQREITTANLATLLDATLLHLASSLGLVGFLLEDPTIMTAYEVS-KDRATRDAFRRVPEPLTRENESRENQK-RSQRRELRFQAAERRRL Conco1 QREHFKTDHRYNLKLKEITEERFEDISPYIWFFGILSRILCVILVGGGHFSAAVFNPIVSKSYHRYTTRRKQGGGQSRNDQA-KGAKSAGAQIRRENEMILKS-DIKKLLIN--W--KQYLDHTSVIWFRGYKST-IMDERVMRIPFTTKRPTYKEVVRELNKVKLSNLIELTLLHVASKNNIIQFLLFNPAIGFPYQLA-TNKNTKNAFRAIPPSVTQERAEKSKEK-VKEKREKRARAAEERIR Conpu1 QRSHFRSDHRYNVKIRLVTEAAFDELTAIVWFIGVYRLLFALFMTAGGHFAGAIVRILLHKTFHRYTTRKKQGGSQGLNDNA-KGAISAGAMLRRYGERALRD-DIRGLIEA--W--ADEIHQCERIWIRANRRI-FLDDRLRTFPFPTNRPTQSELSRELIQVRLFEMVTKSLLQVAAQAEVVQWLLADPTIRTAYDLA-HSKAVRNVFRHVPSALTKERDDKKKDK-IRERRERRARAAEARLR Copci QRLHFKSDHRYNVKMKMVTEANFNQLTALAWFIGVYRALFAVFMVAGGHFAGALVRVLRHKTFHRYTTRRKQGGSQSVNDNA-KGAKSAGAQLRRYGEQALRE-DIRNLLSD--W--AEDIDECERIWIRANRRI-FLDDRLRTFPFPTRRPTQSELTRELTKVRLLEMVSKTLLQLAASAGVVQWLLADPTIRTAYDLS-KTKAVRDVFRHIPSVLSQDQEQKKKDK-VKERRERRARAAEARLK Croqu1 QRAHFRSDHRYNLK---LKEPEFFAISPLVWFFGIYRCILTMLMVSGGHFAGMVVSILEHKTFHRYTTRRKQGGGQAAHDTGGKGAKSAGANLRRYNEQALTE-EIRALLAS--W--SEALRSSELIFIRANSKI-FFDPRLRTLPFPTRRPTLNELKRELTRVRVMDMVQKSVLHVAAMAEVVEWLLCDPTSMTAYEVA-GGRGTRNVFRRVPSGLTEEQSAKGKEK-LRERRERRARAAEARMK CryneH991 QRAHFKSDHRYNVKVKLISLEEWDNMTAVIWFFGVHRALFTFLMVAGGHFAGMVVGVLKHKTFHRYTTRKKQGGSQAINDNN-KSAISAGAMLRRYGEQALQE-EIRALLID--W--ADDIHASERIFIRAGKKS-FWDERIRTFPFPTRRPTLQELLRELTRVRLDEMVRKYLLSAASSSSVLTYFLFNPTLKRPYDLA-SSKVIRDIYRRVPPGLSEEQREKKAEK-LKERRERRARAAEARFG Crypa2 QRGHQKSDHHYNLKQKLVTEADFEKLPPMMWFFGIYRVLFFLCMIGGGHFAAMVVSVLAHKTFHRYTTRRKQGGSQSANDNA-KGAHSAGSSLRRYNEQALVD-DVRQLLSD--W--KGLLDTSDLLFIRANRRT-LFDPRIRGYPFSTRRATQNELMRELTRLQLQALIRRTPLHLAAAQNLVVGLLADPTLKMAFELA-GERGTRDAFRRVPAAMKREREEREREA-ERRKRERRARAAEERLR Debha1 KRDHYRSDHRLNLKRSILSESEFDRLSPFIYFFGVYKSVFALLMIGGGHFAGAIISIIESKTFHRYTTRKKQGGSQSASDNA-RGANSAGSSIRRYNEQALTR-EVRDLLMS--W--KGHIDDCTNIYIRASRRI-LVDDRIRSFPFTTKRATTSELKKNLSYLELIGFLKKTLLHFASSQGMVQVLIADPTIKTPFELA-GNTATRRAFQKVGSPKSKEKEEQKKEL-AKRTREQRARAAEARMK Dekbr2 VESNNLSDDKYNEKRARLTETEFEAKSSFVLFYGVYKTTLALFMIGGGHFAGAIINIAEHKTFHRYTTRRKQGGSQSTSDNA-RGANSAGSTLRRYNEQALRE-EVQDLLKS--W--KPLLDRCDRIFIKAARQS-LLDPRVRIFPFTTKRPTTKELRRELSYLQLISLLKKTMLHYAAHFGMCQVLLADPTIYTAYEMS-ADEKTKYVFEKVPGSKSREESREKLET-ARKQREQRARAIEARMK Dicdi RNVHYRSGHRYNLNLRLVTEEDYNVL-PKLKILSVWKCLLVVLLCSGGRFAGAVY-CIDHKTFHRYTMRKKQGGSQSKKDSE-GGKKSAGAGIRRYNEKRLKE-EVAQLLST--WKDENHFKQCSHIFVFATRDI-LFDERIRVIPFPIIRPTFSEAQRWISSVKVKYLLEKTPLHKAAIDGMIELLLADPTLDVPYDCS-SNQKTRDTFRHIV-PLTKQKEEKIKEK-DKIKREKQALAAERRYG Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 QRSHFRSDHRYNVKVKLVSETEFAALTALTWFIGIYRAVFAMFMVAGGHFAGLVVRILCHKTFHRYTTRRKQGGSQSLNDNA-KGAKSAGAQLRRYGEQALRD-DIRNLISE--W--SEDISACERIWIRANRRI-FMDPRLRTFPFPTRRPTQAELSRELTKVRLLDMIKKTLLQLAASSRVTTWLLADPTIRTAYDIS-STRAVRDAFRHIPSILSAERDNKKKDK-IRERRERRARAAEARMK Fusgr1 QRGHLKSDHHYNLKQKLVSEAEFEKLPPLIWFFGMYRAILFLCMIGGGHFAAMVVSVLAHKTFHRYTTRRKQGGSQSANDNA-KGAHSAGSSLRRYNEQALVE-DVRNLLQE--W--KALIDTSELLFIRANRRT-LFDTRLRGFPFSTRRATQNELMRELTRLQLQAFVRRRPLHLAAAQNLVLGLLADPTIKTPFELA-GERSTRDAFRKVPPAMTKARDEREKEA-ERRKRERRARAAEERLR Galma1 QRAHFRSDHRYNVKTRLVSEAAFGQLTALTWFIGLYRTILAMFMVAGGHFAGAVVRILLHKTFHRYTTRRKQGGSQSTNDNA-KGAKSAGALLRRYGEQALRD-DIRNLLQE--W--AEDIASCERIWIRANRKI-FYDERLRTFPFPTRRPTQSEITRELTRARLLEMVNKTILQLTVQNGLVQWLLADPTIRVAYDLA-RTKPIRDVFRHVPSALSQEQEEKKKDR-VKERRERRARAAEARLK Ganpr1 QRVHFKSDHRFNVKRRLVSEEVFDDLRPVFAF----DGVLTIVLLSSGHFAIATFQPVLSKSFHRYTTRRKQGGSQSTMDSS-KGANSAGAGLRRYNEKALME-EVRGALESAEW--KKLIANSERVFYHANRQV-IF---LRTLPFPTKRPTLTELQREISTVKLLDFASRTLLHTSSKAATVTALLANPTK-TPYELA-PDRPTRDVFRRVAEPLTPERDKKEAEK-EKARREKRALAAEWRVR Gloin1 QREHYKLDHRFNVKMRAITEEEFEELSPMT--LGIYKNILTMLMIRGGHFAALILDVIVHKTFHRYTTRRKQGGSQASNDNT-KGAKSAGAELRRYNESALQK-SIRVLIEQ--W--KSMIEESELIFIHANKNI-IYDRRIRSFPFSTKRPTFTELRKELTRVKMIQLIKKTLLHLASYLGIVEYLLADPTIVTPYDLA-NDKETRNIFRHVPSPLTKEQQNKLK---EKKKRERRARAAEARLK Hisca1 QRDHVKSDHRYNLKSRLLNEVEFNKAHPLLWFLGIYRALFFLCMIGGGHFAAMIVAVLAHKTFHRYTTRRKQGGSQSAADAA-HGAHSAGASIRRYNEAALQA-EIRQLLGS--W--KEMIDQAQLLFVRANRRI-LFDSRLRGFPFTTRRATQGELMRELTRVQIQALIRRTPLHLAASSNTVLALLSDPTLKPPFDLA-GDRPTRDTFRHVPPPLSKTRTEREREA-SRRKRERRARAAEERIR Klula1 PRYHFKTDHKFNIKRRVVDEQEFRQLSPLIFMFGAYKVLFVLFMIGGGHFAGAVVSFLEQKTFHRYTTRRKQGGSQSANDNA-KGANSAGSTLRRYNEAALKA-DIQALLKD--W--EPYIAKCDNIFIRADRKI-FLDVKLKSFPFTTMRPSSNELRRQLTYLKLISFIQKTMLHYASSHGMVLVLLADPTIKTAWDLA-SDTMVKETFQHVSGALSAEEEEKEKQA-AKERREQRARAAEARMK Lacbi2 QRTHFRSDHRYNVKVRLVTEAIFGELTAVTWFLGIYRALFAMFMVAGGHFAGALVQVLRHKTFHRYTTRRKQGGSQSTNDNA-KGAKSAGAQLRRYGEQALRE-DIRNLLNE--W--AEDIEGCERIWIRANRKI-FLDPRLRTFPFPTRRPTQAELTRELTRTRLLEMIHKTLLQVGTQAGVTQWLLADPTIRTAYDLA-RTKPLRDVFRRVPSALSKEQEEKKKER-VRERRERRARAAEARMK Lenti61 QRAHFRSDHRYNVKIRLVAEAHFSQLTPLVWFIGMYKMIFAMFMTAGGHFAGAIVRVLKHKTFHRYTTRRKQGGSQGLNDNS-KSAISAGAMLRRYGEQALRD-DIRNLLQD--W--ADDIHDCERIFIRANRRI-FLDERLRTFPFPTRRPTQAELLRELTRVRLLDMIKRTLLQVATHSDIVKWLLADPTLRTAYDLA-RTKAVRNVFRRVPSVLSSEREEKKKDK-VKERRERRARAAETRLK Malgl1 QRSHFRSLHRYNLVVRQVSREELDQMSPMWWYLGIYRDVLTFIMMGGGHFAVATIAVLAHKTFHRYTTRRKQGGSQAAQDST-GRAKSAGANLRRYGEAQLTH-DIHQLLNRRAW--RDLIARSEHVWVRAAHGV-LWLGALSHIPIATQRPTMSEILRELTRIRLVTMVRRTLLQLAAAADMVHYLLADPTLRTAYDLC-GGKASRTVFRRVPSALTAEQSSKAREK-MRERREKRARAAEARMQ Mellp23 QRAHFKSDHRYNVK---LKESEFQAVSPLIWFFGIYRCILAFFMVSGGHFAGMIVS-----------ARRKQGGGQGTHDTSGKGAKSAGANLRRYNEQALTD-EIRDLLAS--W--SQSIANCELLFIRANSKI-FFDPRIRSFPFPTRRPTLNELKRELTRVRFIEMIRKSVLHLAAMWDVVEWLLCDPTIMTPYEVA-SSRTTRNVFRKVPSGLTEEQILKENEK-LKERRERRARAAEARLN Mnele QVLHYKLDHLYNVKQKLITEEEFDARGPHIIFSEISDEVLAVFLYSAQHFAGAVYELLLHKTYHRYTVRAKQGTVQGIRDG--KGPKSYGASLRRYNQIALFN-DIEKLLMD--W--SDTLNECNVIFHRTNRHV-FNKNKIRTIPFTTYRPTLKEAERLLTKVKILAAVKETLLHCSVFSKFVKVLLANPELKTPYELA-SDREVRDEFRKVPSPLTSEQARKKAAA-KNQRRERCLLAAEGRLA Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 QREHVRLDHRYNLKQQLITEQQFENMSPFIWFLGIYKNALTLILIGGGHFAGVVMDVVAHKTFHRYTVRRKQGGSQ----AA-HGANSAGARIRMYNEEALKL-EVRELLEG--W--SHWIKQSECVFVHSNRKV-LYQGRLRSIPFMTRRPTLTELKRELTSVKLIELVKKTILHLAAHHGCVKLLLADPTTFTAYDIA-KDKETRNAFRHVPSALTPEQERKAKDA-ERERRERRANAAEARMA Mucci2 QRQHFSTDHRYNIKRKVITLSEFEMLSALDWFYGVYRHLLTIIMLGGGHFAGCVIDLIQHKTFHRYTTRRKQGGSQSANDNA-KGANSAGAQIRRYNEQLLQQ-EVRAVLSQ--W--HQHIAQSEMVLVHANRKL-VYN--VKSIPFATRRPTLSELKREMTTVKLLSLVRQTLLHIAASVGLVKILLADPTIKTAYEVS-KDKETRNAFRRVPSPLTEKQLAKEKEQ-EKKRREKRARAAEERLK Mydma QRQHYFSDHRVNAHRKTLTEEEFLDYHPLKTFFSIYKNLIVYLLLCAGHFAGAVFNTVAHKTFHRYVIRAKSGTAQSVCDNQ-GGPKSAGSSLRRYNEAALKK-EIQELLLT--W--SDHINSSNRIFYKCGMGT-LFDQRLCKISLPTQRPTLNEIKRKYSKIAIYKWCSQTLLQRAIVTGIVALLLADPSIQLPYDLA--SKNIRREFR----------------------------------- Neucr2 QRSHLKTDHHYNLKQKLVTEAKFEELQPLLWFYGVYKAMFFMCMIGGGHFAAMVVSVLVHKTFHRYTTRRKQGGSQSANDNA-KGAHSAGANLRRYNEQALVE-DVRGLLAE--W--KGLIDTSDLLFIRANRRT-LFDPRIRGFPFMTRRATQNELMRELTRLQIQALVKRTPLHLAASQNLVTGLLADPTIRTAFELA-GDRATRDAFRGVPVALSRDRTEREKED-QRRKRERRARAAEERIR Orpsp11 -------------KLKY------------------------------------------------------------------KG------------------------LVDM-F--QKQLENSSLVDLNE--------------PFYN-----------------------TLLHIASANGMVDFLLANPTIMTAYDMA-SDKETRNTFRHITSFLSPEATRKKQRRIQSQKREKRAQAAMNRLK Pench1 QRSHVRSDHRYNIKAQLLEEIEFAKAHPIFWLLGVYRAIFFMCMIGGGHFAAMLVSVIAHKTFHRYTTRRKQGGSQSASDAS-RGAHSAGSSLRRYNEAALEK-DIREVLSD--W--KGMIDTAELLFVRANRKT-LFDPRLRGFPFNTRRATQGELMRELTRMQLQALIRRTPLHLAANLNVVTALLSDPTARTPFELT-GDRATRDAFRKVPSAVSKARAEKEREA-ARRKRERRARAAEERFK Phybl2 HRKHYNTDHRYNIKRRLVSLIEFEKLSAMVWFLGIYRTLFTILMLGGGHFAGCVVDLVTHKTFHRYTTRRKQGGAQSSNDNA-KGANSAGAQIRRYNEQLLQK-EVRELLSQ--W--KSYIDRSELVLVHANRKI-VYNPAVKTIPFVTKRPTLSELKREISTFKLAGLVKQTLLHMASHYGLVESLLADPTVKTPYEVA-KDKTIRSVFRRVPSPLTLEQLEKEREA-EKIRREKRARAAEERMR Picst3 DTSYYKSDYRYNLKRSLLSEGQFEELNPYILFFGIYKSLFALFMIGGGHFAGAIISVVVSKTFHRYTTRRKQGGSQSASDNA-RGANSAGSSIRRYNEQALIK-EVRELLVE--W--KSYLDKCSTIYIRANRKI-LVDSRLRSFPFTTKRATTSELKRELTYLELIVLLKKTLLHYASANGMVLVLLADPTIKTAAEIA-SDENTRRAFQKVAEAKSKEELEDERQL-AQKTREQRARAAEARFK Plicr1 QRAHFRSDHRYNVKVRLVSEGDFAQLTALSWFIGVYKVLYAMFMVAGGHFAGAIVQVLYHKTFHRYTTRRKQGGSQSVNDNA-KGAKSAGATLRRYGEQALRD-DIRNLIAE--W--ADEINGCERIFIRANRRI-FFDERLRTYPFPTRRPTQSELSRELTRVRLLEMVSKSLLQVAAHAGTTQWLLADPTIRTAYDIA-RTRAVRDVFRRVPSVLSRERDEKKKER-VKERRERRARAAEARLK Polpo RNQHYRSAHRYNIKLKLVTSEEFSAMTPKLSFFTIWRAILAILLCSGGRFSGAVYQAIEHKTLHRYTVRKGQGGSQAKKDQE-GGAGSAGSFLRRYNEKRLRE-EVIGIMRG--W--NAHLKECKKIYIFATRDI-LLDPRIQVVPFPIIRPTFAENQRWLYSVKVIHLLEETALHRAAADGIVKLLMADPTVETVYEVA-SNQ-ARDLLRRIP-PLTKEREENKKEK-EKAKRERRALAAEARLG Pucgr2 QRQHFRSDHRFNLKLSTIDQAKFTNMSPLIWFLGFYRSIFTILMIGGGHFAAMVISILLHKTFHRYTTRRKQGGGQASHDAGGKGAKSAGASLRRYNEQTLFQ-DIQALLKA--W--NEPISQSDLVFIRSNLKT-FFDPRVRSLPFVTKRPTFNELKRELTRVRAVEMVKKSLLQLASMADMVEWMLSDPTILTAYELA-PSRLTRNAFRKVPSALTEEQSNKNKER-LKERRERRARAAEARLK Punst1 QRAHFRSDHRYNVKMRLVAEEDFGALTALVWFLGIYKRLFAMFMTAGGHFAGSIVRILKHKTFHRYTTRRKQGGSQSLNDQA-KGAKSAGAQLRRYGEQALAD-DIRALLLE--W--AEDIDACERIWIRANRRI-FVDDRLRTFPFPTRRPTQAEISRELTRVRAVEMIRKTLLQVAAHAGVTRWLLADPTVRTAYDLA-RTRGVRNVFRHVQSALTKERGEKKKDK-IRERRERRARAAEARLK Rhior3 QRSHYNTDHRYNIKRKLISFEEFERLSALSWFYGIYHHLLTIFMLGGGHFAACVIDFAEHKTIHRYTTRRKQGGSQSANDNA-RGANSAGAQIRRYNEQMLQQ-EVRQIVSQ--W--REKIQASEFVFVHANRNV-LFN--TKSIPFVTRRPTLNELKRELVTVKLINTVKQTLLHMVAAMGLVSELLADPTIKTAYEVS-KDKETRNAFRRVPSPLTKEQINKEKEQ-EKKRREKRARAAEERMK Rhoto1 LKQHYRTDYRYNVKLKLVSEQAFNQLSPLEWFYGIHRAALTMLMFGGGHFAGWVISVLESKTFHRYTTRRKQGGGQGANDAA-IGAKSAGAQIRRHNEAMLND-EVGALLTS--W--SSHISSSSLIFLRASYKT-FFDPRIRGFGFPTKRPTLSELGRELTRVRLTEMVRKTLLHLAAAAGLVRLFLASPYPKVPYDLS-PSRPTRNEFRRVPGGLDERRERREEAR-ERERREERARAAEARLK Rozal11 FREHIKSDHVQALKEFLAEKDRYQRY-PFVFFLAMYRHVLCIILLQGGYFASAIYSVIAHKSLHKYTTRKKQGGSQASYD---KGPKSAGANLRRQNEKHLEEQDILKLLGD--W--KVMISECYQIYFSANANI-LFDSRITKIPFEIEKPNFQQVQMELKSL---------------------FVL--------------------------------KVEK---------------------- Sacce1 QKAHYQTDHLMNVKRNLLSVEEFDALSPYIYFLAIYKSLFALFMVGGGHFAGAIVSFLEHKTFHRYTTRRKQGGSQSAMDNA-KGANSAGSALRRYNESALKT-DIQGVLKD--W--EPYLSKCDNIFIRADKKI-FTDERIKSFPFTTNRPTVLELKKELSYLEIISLLKKTMLHYASQQGMALILLCDPTIRTAWDLN-RNDDVRHAFQHIGQPLSREIENEKAEA-AKEKREQRARAAEERMK Salro QTAMLQRQERLKVQNRLGSQGAQQAAGPVLYFCSIYRDVLAFFMLAGGHFAGAIVNIQHHKCFHRYVVRAKRGTVQSVRDAK-SGPKSAGSNLRRYNEQQLRQ-DIEGLLRE--W--KPYLASCTVIFHRTNRSF-IFDPRIRTVPFPTQRPTLKEIARLLTCI------------------------GEPAFKTTGDAA--------------------KEEQRKEN-DAEK-QQSAVVASTQTI Schco3 QRAHFRSDHRYNVKARLVSEAEFASMQAITWFIGVYRAIFAMFMVAGGHFAAAIVRVLRHKTFHRYTTRRKQGGSQSLNDNA-KSAVSAGAMLRRYGEQALRD-DIRGLIDE--W--AEDIAACERIWIRANRKI-FLDARLRTFPFPTRRPTQAEIARELVRVRLLDMVTRTLLQLATREGVVRWLLADPTVRTAYDLA-RTREVRDVFRHVPSALTRDREEKKKEK-IKERRERRARAAEARLK Schpo1 RKSHIKSDHRFNTKRKIVSQDEFESISPLTWFIGVYKHMFAMFMVGGGHFAAMIASVLAQKTIHRYTTRRKQGGSQGAADNT-KGIHSAGSGLRRYNEQALIK-DIQQVFKD--W--GKLLETCDLIFVRANRSI-FFDPKLRVFPFTTKRATHSELLRELVTPVIISNLKATPLHYAVTQKLVAKLLADPAMKTPFEISTGNKEVKDEFLKVGAPQSREQRQKAKEE-LRRKREKRAAAA---MK Sorma QRSHLKTDHHYNLKQKLVTEAKFEELQPLLWFYGVYKAMLFMCMIGGGHFAAMIIAVLVHKTFHRYTTRRKQGGSQSANDNA-KGAHSAGANLRRYNEQALVE-DVRGLLAE--W--KGLIDTSELLFIRANRRT-LFDPRIRGFPFMTRRATQNELMRELTRLQIQALVKRTPLHLAASQNLVTGLLADPTIRTAFELA-GDRAIRDAFRKVPVGLSRDRMEREKED-QRRKRERRARAAEERIK Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 MRTHYKSDHRYNIKRKVVSEEQFDDLSPFV--LLVYKQIFTLLMLAAGHFAGTVVNAIVHKTFHRYTTRRKQGGAQSSNDQA-KGANSAGAGLRRYNEQALQK-EIRDLLVE--W--KDYLSTSDLIFIRASRKV-LFHDRIRSFPFTTRRPTFSELMRELTTIKLADFCKRSLLHLAATNGMVNALLADPTMLKPYDVA-QSKDTRDAFRHVPGPLTPEQKEKEK---EKKKREKRALAAEARIR Sporo1 LKEHYRTDYKYNVKLKLVSEHDFNQLTALLWFYGVYRTILTLLMFGGGHFAGMVVKILEKKTFHRYTTRRKQGGSQGMHDSG-NGAKSAGAQIRRHNEAALTD-EVRELLND--W--REEIDDSELIFLRCYYRV-FMDPRIRGFTFPTRRPTIAELVRELTKVRLIEMVQKTLLHVASWADLVRWLLADPTLRTPYELA-RSKATRNEFRRVPSGLDEAKEAKEEEK-QRERREERARAAEARLK Stehi1 QRTHFRSDHRYNVKIRLVSATDFARLTALVWFIGIYRAIYAMFMVAGGHFAGAIARVLKHKTFHRYTTRRKQGGSQSLNDQA-KGAKNAGAQLRRYGETALRD-DIRGLLTE--W--ADELNQCERIWIRANKRI-FYDDRLRGYPFPTRRPTQSEVSRELTRVRLLDMIIRTLLQFAVQAGITRWLLADPTIRTAYDVA-RTKELRDVFRRVPSALSKEKDEKKKDK-VKERRERRARAVEERLK Tapde11 --------------------------SPISWYIGVYKAMLAMFMVGGGHFQGTIISIKASKGFHRYTTRRKQGGAQSTNDNA-KGANSAGAQIRRYNEIALAQ-DVRELLKE--W--NSLLATVDIILVRASKKL-L-DPRVRGFPLNTRRATQSEIIRILSRLKLTTLIKRNLLHFAAFTEAISVLLADPRIKTAFEVA-GSKEARDSFRRVPAGLTSERKARQVED-QRRRRERRARAAEARFK Thetr TRELFPDDEASNFVFDRWKSSQFATIASLAWH--------VVIMCHGGYFAVAHFVLREHKTMRKYVTRRKQGGRQSNRDRS--GMFSAGSHLRRTNEEKLAR-NIKELLAGQAW--ASALAAAQRILLCANREI-FFDPRIRGIPIKTNRPATAECVRLMTAV--------TLRTIVATPG----LL--PTHRSPHPVA-----------TGSAALTASSSASGEDAIYAEERERNP-------- Treme1 QREHFQSDHRYNMKIKQVTAEQFDQMTAIIWFFGIHRALFTLLMVAGGHFAGMVVGVLQHKTFHRYTTRKKQGGSQSINDNA-KSAISAGAMLRRYGEQALQE-EIRALMVE--W--KEDIDLSERIFIRAGRKS-FWDPRIRVFPFPTRRPTQSELLRELIRVRLEEMIIKDVLSIASQAGIVKFLLVDPTLRRSYDVA-STKGVRNVFRHVPSGLSEEQEQKKMEK-MKERREKRARAAEARFK Trire2 QRSHIKSDHNYNLKQKLVSEAEFEKLPALIWFFGIYRAIFFLCMIGGGHFAAMVVSVLAHKTFHRYTTRRKQGGSQSANDNA-KGAHSVGSSLRRYNETALVE-DVRALLQD--W--KGLLDSSELLFIRANRRT-LFDARIRGFPFSTRRATQNELMRELTRLQLQAFVRRRLLHYAAAQNLVLGILANPLLKTPFELA-GDRSTRDAFRKVPPAMTKDRDEREKES-DRRKRERRARAAEERIK Umbra1 QRAHFRSDHRYNVKRSIVSEQQFQDMSPLSWYLGVYNSARTMIMVGGGHFAAAVIDVIAHKTFHRYTTRRKQGGAQSANDNA-NGASSAGSQIRRYNEVALKQ-EIRELLSQ--W--RKYLQESDTIFVHANKKI-IYDKRIQSFPFTTHRPTLNEIKRELTDLKAVLLTKQTLLHVASSHGVANFLLADPTVKVPYDLC-KDKLVRNAFRKVPSPLTAEQLEKEEEQ-EARQRELRLRAAEARRA Ustma22 QRAHFRSDHRYNVQLNVVSEQVFEKLAPLLWFLGFHRNAFTVLLLGGGHFAASVIALLAHKAFHRYTTRRKQGGGQAAQDAT-GRAKSAGAQLRRYNEAALGD-DIRDLLDSPGW--RELVSRSEKIWIRAARGL-LWDGRLGSLPFPTRRPTIGETVRELAKVRLVEMIRKTLLQLAAEAGVLRYLLANPTLRAAYDLC-STKEVRNVFRRVPSALTEEQSAKQKEK-ARERREKRARAAEERMK Walse1 LRMHFHSDYRYCVKLKAVSEDGFEEMTPLVWFLGIYRALFTLIMIGGGHFAACVVSVLKQKTFHRYTTRRKQGGAQSSNDMA-KGANSAGAMIRRYNEQALAD-DVRELLNE--W--KEDVDASERIFVRANRRI-LFDPRVRGFPFPTRRPTHNELIRELTKVKAIEMTSKNLLQVASLNNIINWLLVDPTARTAYELA-KGKESRDAFRRVPSALTPETSAKDKDR-MKEKRERRARAAEARMA Zygro1 RRGHFKTSHTFNVKRSLVSQIEFEEISSQLYFFGLYKSLFALFMMGGGHFAGAIVSFIEHKTFHRYTTRRKQGGSQSAMDNA-KGANSAGSSLRRYNEAALRS-DIHNLLKE--W--KPYLAKCKNIFLRADKRL-FIDQRLKSFPFTTGRPNVAELKRELTHLQLLSLLNKTLLHYASQQGMVTILLANPCLKTPWDVS-KNSQTRYSFQHVKEPLSRERANSEADA-ARIRREQRARAAEARMN [Cluster2533.fasta_al_trimmed; alignment length = 185] Allma1 YGAHQMYLTVCNRYVKGK--RITAVDLLANGARLLCEHKQYGSALDMTNVIL-KTWTDELLFDLLDARDLAKHAIKWTAKC-GEFASGEPALHHQIGVILAGVAQRHFILGTTDSAESLAVLI-------TLQYLRIAHALTFTKHLPVLNFVQLVIMTAQRLCQQYDLLERVGETVFNILQDIM Ashgo11 YEAHQTLRTVANRYVRGK--KWPAIDLITHGIHTLMGVGQSSSVVDLTRYLL-EVYEQGRLVKILVGRDVCTGMNNWSVRH-GRYTYGDPYLHSVIGKRLLEAAERYFVLGNRDSLEEYVNWLGEFLGRLVFGYLNLKNAYDFLARYPDLNFLQLLLIACQALKSQYQSLVQLGKEFFNVLQDLM Aspfu1 YEAHQQLRVIAARYIKQS--NYEAAEILAGGATALLRAGASASGGDLAIMLVDEVYTKARLIELLREKRFIQEMIGWSGRF-GPVERGDAELHHAAGSVYAEDAEKHLVLGTSESAETLAKLEAIYASRAVFPYLNLRNANKFTSRLPLLNFISMLLLTIQRLTAHYDALSQIGEQYFAILLDMM Aurde31 YEAHQKARTFASRYTKSG--QHAAIEVLFQSARELLKTGQQGSGTDLAVMML-DAYDAARVTQLIALKTVVDKAVAWSAKY-GECPAGDPDLHHYIGELLYKEAEPHLLSGKRDSARLLGQLLGLFAARGTLPYLNILAARAFLATANLLNFLQLAVPTLQRLVGTYKAIQDLSATYFNIFGDLL Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 YEAHQKARTFASRYVKAS--QFDAIQVLFQSARELLKAGHLGSGTDLGLFLI-DVYNTKRLTQLIALKTLIDKSVAWSSTL-GWCPSGDPDLQHYIGELLYKEAEPHLLAGERDSARLLATIMGAYASRGVIPYLNILAARTFLSHLPTLNFLQLAIRTCQRLCGRYEAAAALGKEYFGILQEMM Botci1 YEAHQQTRVVASRYIKSQ--NYPATDILYSVSLSLLQASQGGSGGDLALFLL-EVYNTSRLFTLLRAKRFITETIAWSSKT-SAYPAGDPELHHVIGSLLAEEAERHLILGTKDSAEVLAKMEALWECAGC------------------------------------DPFAR-GE---------- Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 YEAHQTLRTITNRYVKAK--QYKARDLLYQGSTILLKNKEFASASDLINYLI-QIYDEEKLIDLISNSDLAKSSLNWSKKSPGCEKFGDCELHHLFGSKFLKFAELHLVLGTFESVPLYINYLGVFLGRAIVNYSNIKFVKEFLKEIPVLNFLQLLVITLQKLYEQYAPVEYLGKIYFNVLANIM Cangl YEAHQTLRTIANRYVRSK--SYDAIELINQGALSFLKAKQGGSASDLIFYLL-EVYDVARLAQLLVLKDIVTGMNNWSIKH-SEFKFGDPTLHNVIGNKLVAGAERYYMLGTHESVGKYVDLLADYFSRLVMNYLNIAYAYEFLKKFSDLNFLQLLLLTCQTLKEHYNELSYLGQEYFGILQDMM Capow YEAHQMYRSVYARYAAQN--DFDAILLVYTGSTLFFKHGQTGSAGDLAVLML-DAYTAQRIAELFSGDKLVRQSLKWSTAV-GRNTRGDPSLHHLFGTAFWREAESHLVLGTEASALSLAEMLELFITRAVLKYLNLRDANVFTAQHPLLNFCHFLLATLERLREKYASLDAIGQCFFNIISEML Catan2 YSAHQMYLTVCNRYVKGK--KIDAVDLLTNGAKLLCEHKQFGSALDMASVVL-KTWTDERLFELMDLNELMKNGIKWTSKC-GEFSTGEPALHHHVGVTFANVAHRHFMLGTTDSAASVAVLL-------VLQYLRIAHALTFVRHLPVLNFVHLVLLAAQRLCGQYELLERVGETVFGMLQDLM Cioin YEAHQLYNTLFYRYSAKN--KHDARNLLYKGALHLFEHEVHEVTTELAEILG-KMHHEL------------NRAITWSAGCTGMPRFGSKDLRFKFAMNYWEESRQHFLY---DDGQKFGEMLDLFLTQAVLQLLCEKAAEDYTKIIPIINFLFFLLRAVKELCDNYKYLEKIGEIYFDV-ENLM CocheC53 YEAHQQLRVIASRYTKAS--DWTATSILFQGAQSLLQAGQGGSGGDLCIFLL-DVYNKGRLLTLLRAKKFVGEMIVWSSRF-GDFPAGDPELHHVAGGLYAEEAERHLLLGTQDSAATLASLHPLYCARGVLPYLNLRAANKFTSAVPLLNFLGLLLLSVERLKSHYEALDQIGEMYFGIMFDML Coere1 YEGHQELRAIAIRLVKQK--KHEAIQLLYLGALELCQYNQWGSVADLTTFMI-NIYVEERIYDIFEKPRVYESAIQWSIGV-MGNSVGDPQLHHFIGCIMRNKAEQHYLVGTPESPAALGNMLGTFVARGVLKYLWYDAACLFVSRLELVNFVQLLLLTVERLRSQYELLDIIAEKYFGVLFDIV Conco1 ---------------------------------------------------L----------------------------------------------------------IDSSNAEAYAKLVGYFLIRSIISLLQVDYAKLYLNQIKLINLSQLTILLLDKLQSEFDSYAKLGELYFGVLQSLM Conpu1 YEAHQKARTFAARYVKSG--QHAAIDVLFQSARELFKIGQQGSGTDLTVFLL-DTYETGRLTQLIALKQVIDRSIAWSAKA-GPCPAGDQDLQHYAGEVLYKDAEPHLLAGKRDSARLLAEMFGAFALRGTIPYLNILAARTFVSAVPLLNFCQLAVLACQRLCGTYVALNEIAQLYFGILGAML Copci YEAHQKARTFASRYVKSG--QHDAIDVLFQSARELLKTGQPGSGVDLGGFML-DVYDTKRVTQLIALKTLIDKAIAWSAKH-GDCPAGDPELNYYVGELLDKEAEPYLLAGTRDSARLLAEMFGPFALRGVIPYLNVLAAKAFVSGLSLINFSQMAVLTCQRLCGTYRALTEIAQLYFAILGDMI Croqu1 YAAHQKYRTSAARLLKSS--EATAISLLFEGSRLLLQRQQLGSGTDLALMLIRDVYVGRKLLNLIALKTIIDASLSWSSDA-GQCPTGDPVLHLTVGELLAKEASVHLLSCNQDAARALSGVMGRYAARGVLGYLSILVARTFLAKVPALNFLQLLILTCQVMIGRYETLDVLAQMYFGILNDLM CryneH991 YSAHQKALTTTARLLHASPPQYDAIEILFAVAKELLKAGEAGSGSELGVRMI-TIMGEANVTQLLALKKLIEASVKWTQAH-GQCPSGDPQLQQYIGEMYYKEAEQHLLAGKRDASIVLADMMGPFALRGILPPLSIVPAFTFLAHLQSLNFAQLALVTIQHLCARYEALSQIATEVFLILQNLM Crypa2 YEAQQQTRVVAARYIKAK--NWDAIDILFGVSQSLLKAGQGGSGGDLCVLLV-DVYKQARLLTCLRLKKFVDQMLAWSSKF-GEFPAGDPDLHHVAGTIYAEEAERHLLLGTRDSAEVLTRMEAAYLARAILPYLNVRAANTFTSLLPLLNFLGMLLLAVQRLQTKYEALEIIAEMYFGILLDMM Debha1 YEAHQTLRTITNRYVKSN--QYNAIDLLYQGSSILSSNKEYASASDLISYLI-TVYEESKLIELISLPDLAKNSISWSQT--DKYKFGDCDLHHAFGIKFLNSAESHLILGTHESLPFYINFLGIFMSRAVINYANVKFVQEFMSKLQFVNFLQLLSITLTKLYEQYGPVEYLGRLYFGLLANLM Dekbr2 YEAQQTIRAITNRYVYAK--NYDATELLYQSSMILTEYKKYDEASDLFLYLL-EVFTMEKIEDFLNAFNLANETFKFARKQ-CQNEVGFPRLNKLVGEKLYYSSQKFLVFDDLSDVKLLAALYGTYLAQIATPYLHASFAKELIKKLKLVNFLQSSVETCEHLFTRYYTINAIGQLYFNVLRSMM Dicdi YDILQSYKALYNRFSTQK--KYKTVTLLESGCNKFLEYKQWNCAADLAKLLI-ECYKNFPIIKIFKNISFMRDAIEWSSKN-GGDSKGSEEFHTLLAITLSEEAQKHFIFGND--YFSFCEMLDLYITRAIFGLLKLKQASDFTTKVPLLNFDRFLLLTLERLRQKYKFLDQIANIFYNVLSGML Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 YEAHQKARTFASRYIKSA--QYDAIDVLFQSSRALLTAGQPGSGTDLALFLI-EVYEAKELTQLIALKTLIDKAVTWTAKA-GPCPAGDPDLNHYVGELLYKDAEPHLLAGKRDSARVLAQMMGPFALRGTIPYLNVLAARTLLS--SLLNFLQLAVRTCQRLCGTYKHLNELATLFFGLFGDML Fusgr1 YEAQQQTRVAASRYIKTS--NWPAIDILSSVSQALLRAGQGGSGGDLCAMLV-DVYKQARLLTCLRLKKFVGEIIGWSAKF-GDYPAGDPELHHVAGSLYAEEAEKHLLLGTKDSPEVLTKMEALFAGRAVLPYLNVRAANTFTSSLPLLNFLGFLLLAIQRLVSKYEALEMVGEMYFGLLMDMM Galma1 YEAHQKARTFASRYVKSN--QYDAIDVLFQSARELLKTGQTGSGCDLTSFML-DVYETKRLTQVIALKTMIDKSIAWSAKH-GTCPAGDPELQHYVGELLYKEAEVHFLAGKRDSARLLAEMFGIFALRGTIPYLNVLAAKTFTAALSLVNFAEMAVLTCQRLCGTYMSLNEIATLYFAIFGDMM Ganpr1 YEAHQMYLSVAQRYIKAK--KYTAQSLLHSGITNFTRYAEHGSAQSLLSSLL-DVWDHATLTELAEGEQVVKDVVRWTAKN-GKDKNGDAEFHHAAGMRFYKAAEHHLVLGTPDSAKIAALMAGYFEARNVLQYIRLNHASLFLSNLPMLNLVQLIYATVQRVRKIYKLLDKIGESYFQILNMLF Gloin1 YEAHQMYRTVCRRYIKQR--KYMAIDLLYSGAETLLKHKQTGSGIDLSLYLI-DAYNEERIIQLLELKRFIDVAISWTVKF-GENPAGDPELHHFVGELFWKDAEPHFLAGNAESSKSYGKMLGAYIARAVLQYLSIREAKTFIAEISLLNFLQLLILTVQRLRNKYELLNKIGEIFFNLIQDLM Hisca1 YEAHQQLRVIAARYLKQQ--NYDAADILAGGAKALLRVPASASGGDLAIMLIIDVYNKARLIELLRERRYMNELISWSARF-GKLERGDPEIHHEIGVLFAQEAERHLAIGTPASAEILADLEGTYASRAVFPFLNLRDANKFTSRLPILNFTSLLLLAIQRLTRQYSALAHIGELYFGILMDMM Klula1 YEAHQTLRTIANRYVRAK--KYDSIDLISHAAGAFLRSKQGGSGSDLIFYLL-EVYDLARLIQLLVLKDVVTGMNNWSVKH-SEYKFGDPYLHSAIATKLLEGAERYLVLGTHDSMKRYVDLLPDFISRMIFNYLNIEYALELLKRFESLNFLQLLIIACQTLKSQYSELQFLGQEYFGILQDMM Lacbi2 YEAHQKARTFASRYVKSG--QYDAIDVLFQSARELLRTGQPGSGVDLTGFML-DVYETKRLTQLIAMKTIIDKSIAWSAKH-GPCPAGDPDLHHYVGELLYKEAEVHLLAGKRDSARLLAEMFGVFALRGIIPYLNILAARILTSALPIVNFSQMAVLTCQRLCGTYQALSELGNLYFAILGEMM Lenti61 YEAHQKARTFAARYNKSS--QYDAIDVIFQSARELLKVGQQGSGTDLASFLV-DVYENKRLTQLIALKTIIDKAIGWSAKA-GPHPAGDPDLHHYVGELLYKEAEQHFLAGKRDSARLLAEMFEPFALRGTIPYLNILAARMLVSQLPAVNFAQLAVRTCQRLCGTYKALIEIAELYFAILADMM Malgl1 YELHQKLRTKTVRLMRKN--KHNAVETLHSGAIQLLDMNEEGSACDLAEYLL-EVYMQARINSILEKRKTVMAANKWAISA-TQNPLGDEKLRLFLAELLARDAETHFIA--DNASK-FAHMLGTFALRGWVPLLAPESARAYVQNAPSLNFSQNAVALICDLLRQFQLLSQISGIYFGLLSSMF Mellp23 YAAHQKYRTSAARLLKSN--EPQAISLLFEGSKLLLQRHQLGSGTDLGLMLIRDVYVSRKLLNLIALKMIIDSSISYSTTS-PDFPSGDPALHFSIGEIYAKEAEIHLLSGDQDSAKSLSNVLGRYAGRGVIGYLSITSAKSFLNKSPSLNFLQLLILTCQIMVGRYESLDLIAEMYFGILNDLM Mnele -----------------------------------------------------------KLIEIIRKQRFIPKVFKWSKMY---TEHGDPRIHRACAEMYLLECCTHCQYLDLDGVEFYSQTLGLIITWAVL----------------------------------------------------- Monbr YEASQLVLSLASRLHALE--RDAAVGELRNVLQQLIDHGQDKEVVSLARTMV-TTPEYRRQAKVLAL------IQNWAGSP-DQQTAAHVALWEAMATALAPRAQASDVLAVLASLVRLCEMLKGYINRAALFSL-LGLVRRCMAPLPLAEFVDRVLATLTRLRVAYPLLDRIAAYYYNHIRTMS Morel2 YEAHQMYRTVANRYVKAH--NYKAIDLLRSGSLLLLKHKQVGSGTDLALYLV-EVYNLDRIFDLADLKTFLQNAISWSANN-SEYKNGDPLLQHYIGLLFWKEAEAHLLVGTQESAEALGLTLGAYLMRGVLQELNLRDANTFVERLSLLNLTQMLLLACETIAAKYALMTTIGELFFNILADLM Mucci2 YEAQQMYRTVARRYNKQQ--KYATIRLLHDGAILLLQHKQNGSGSDLANYML-DTYKLARVVEILSLKTFISNAFRWTKAE-GDYPEGDPELHDFVGTMFYNEAEDHLLVGTDHSAELIGKLAGIYLARIVLQFLDIHYATLFIQAGPWINFTQMLLLTVQRLKTKYDLVQEIGLVFFNIMQDLM Mydma YEASQMTKTLYFRYKSQK--KYEAEYILYDSVIILLEH-QHESAFDLGRLLV-KLYTETKICKILSLNDYISEALSWSSQ-EGY-KYGHPQLHSVIANKYWQEARKHFSY---NDGCQCAMFLDLFVTQAVLQFLNQPTANTYT---PLLNFIAFLLLIIEKLCEHYQYLDKIGQIFFGILDNLM Neucr2 YEAGQETRLVAARYTKAE--NWPAIDILSSVSQALLKAGAGGAGGDLAILLV-DVYKQGRLLTCLRLKKFVKEVFDWSRKF-GDYPAGDPELHHVVGTLAAEKAEKHLVLGTKESAEVLTRMEALFAARAILPYLNVRAANTFVSALPLLNLLGLLLLAVQKLKTKYGALEMIAEMYFGILLDMM Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YEAHQQLRVIAVRYIKQS--NYDAAEILAGGAKELLKAGASASGGDLAIMLVLEVYNKARLIELLREKRFIQEMVGWSAKF-GPLERGDPDLHHAVGSVYAEDAEKHLILGTSESAETLAKLEAIYASRAVFPYLNIRSANKFTSRLPLMNFITMLLLAIQRLTGHYDALAQIGEQYFAILMDMM Phybl2 YESHQMYRTVARRYNKQQ--KHQAIQLLHDGAVSLMTHKQSASGSDLANYML-ETYNTARVVEILGLKSFINNAFSWTQKH-GQYPEGDPELHDYVGTMFFNEAEEHLLVGTDHSAELLGKLAGLYIARGALQYLNIHHATLFLKCSPWLNFLQLMILTVQRLRSTYELLDDIGNVFFDILQDML Picst3 YEAHQTLRTITNRYVKAK--QYQAIDLLYQGSSILSKNKEYASSSDLISYLI-QVFVESKLIELITHNDLAKQALKWSQGKDEKDKFGDVDLHHIFGAKYLNYTELHLILGTYESLPLYVNYLGLFLSRAVINYANIKFANEFLKQLPILSFLQLLLVTLGKLYNHYPPVEYLGKLYFGLLANLM Plicr1 YEAHQKARTFAARYAKSH--QYDAIDVLFQSARELLKAGEQGSGTDLAGFLI-DVYETKRLRQLIVLKTTIDKSIQWSAKH-GPCPAGDQDLHLYVGELLYKDAEPHFLAGKRDSARLLAQMFGAFALRGTLPYLNILAARTFVAQLPVVNFAQLAVLTCQRLCGTYVVLQELGQLYFAIFGDML Polpo YDLLQSYKALYFRNASAK--KYKTISLLLSGATNFLKYQQWNCAAELGQLLI-ETYKSFTVSTLFKGITFMRDAIKWSESA-GAGDKGSDEFHALLAIAMAKNAQKHFIFGND--PISFADMLDLYIARA---------SADFQSFVPLLNYIRFLLLTLQRLKQKYKYLEQIANLYYNVLGSLL Pucgr2 YAAHQKYRTSAARLLKSN--EQAAISLLFEGSRLLLERGQTGSGTDLGLMLIRDVLVAKKLLTLITLKTLIDAAVSWTCDA-GDCPTGDPALHLAVGERLFKEAVIHLLSCNRDAAKVLSNVLGRYAAVGVLGYLSIISARSFLQKTPSLNFLQLLILTCQVMIGRYESFATLAEMYFGILSDLM Punst1 YEAHQKARTFASRYQKSR--QFDAIDVLFQSARELLKAGQPGSGTDLASFLL-EVYENKRLTQLIALKTLIDKAVAWSAKH-GPCPAGDPDLQHYVGELLYKEAEPHLLAGKRDSARVLAQMFGTFALRGVLPYLNILAARTFTRQILVLNWSQLAVRTCQRLCGTYGILMEIAQLYFAIFGDML Rhior3 YEAHQMYRTVARRYNKQQ--KYETIRLLHDGAILLLQHKQNGSGSDLANYML-DTYKLARIVEILNLKPFISNAIRWTKDD-EHYPDGDPELHDFVGTMLYNEAEEHLLLGTEHSAGLLGTLAGIYLARVVLQYVDIHYANLFIKAGSWINFTQLLLLTIQRLKSKYELMDDIGLVYFNILQEMM Rhoto1 YSAHQKARTSATRLLAPP--RRNAAELLWDAARKLLENGQTGSGVDLGVMLVDDVWTARKLIQLIALKTLTDAIFAWSAKT-GSGAAGDMEIHQYLGETFFKEASLHLLVPSQDAAQTLANVMGRYAARGTLSYLFILAARTFLALVASLNFLQLVIRDVQALVGKYEGLTALGEIHFGLLMDMM Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 YEAHQTLRTIANRYVRSK--SYEAIELISQGALSFLKAKQGGSGTDLIFYLL-EVYDLARLVRLIAEKDVITGMNNWSIKF-SEYKFGDPYLHNTIGSKLLEGAERYFMLGTHDSMIKYVDLLAEFFSRLVFNYLNISFAHEFLERFSDLNFLQLLLITCQTLKNHYSELEFLGQEYFNILQDMM Salro YEAQEVLISLTNRLRAQQ--QFAAKAALEDGMDKLLQNHKDNAVAQLVKVHI-DVLSESRFSDDVSL--FLRHTIAATTPEGG--SHGRCQLHFSAAQSFLRAALEQLVLAKGDVVTTTVDALALLACKHVIRVASRDLGQAYVERARPLEFARYVLLTLTRLRKAYKVLNKVAKRYYGVLPGLL Schco3 YEAHQKARTFAARYVKSN--QLDAIDVLFQSARELLKTGQPGSGVDLAGFML-EVYETKRVTQLIALKSLIDKAVAWSAKH-GAYPSGDPDLHHYIGSLLVKEAEHHLLAGLRDSARLLAESFGNYALKGTLPYLNILAARTFVAQLGVVNFCQAAVLACQRLCGTYRILNEIGGLYFSLMADMM Schpo1 YEGHQMLRTLVNRQVKAK--KHDAVALLYSGAKTLFEIEQTGSAADLAIYML-DVYEKARALTLLGLKQYVKRLLEWSKSA-G--PQGDKDVHFAVATMFVKWAEKHFVLGNEKSARAYGETMDTFAGRPVLNYLNLISAWNFTKHFPQMNFLHLLIFTAYRLVQKYAALAKIEEIYFGILANLM Sorma YEAGQETRLVAARYTKAE--NWPAIDILSSVSQALLKAGAGGAGGDLAILLV-DVYKQGRLLTCLRLKKFVKEVFDWSRKF-GDYPAGDPELHHVVGTLAAESAEKHLILGTKESAEVLTRMEALFAARAILPYLNVRAANTFVSALPLLNFLGLLLLAVQKLKTKYGALEMIAEMYFGILLDMM Sphar YEAHQMYRTVYFRYYGQE--KYGALQTLSEGARLLLNKGQYSSGCDLALTIV-EVYSNTRITSIYPLERFVTRALAWTVDE-GTNTRGDPQLHHLFGMQYYKEAISHLIYGTDVSARALGDVLDSVIAQPLLKLIDLQSANTVISKHPLVDLVQCLLVLCQHLKNSYKYVNRIGESYYRIFGDLM Spipu1 YEAHQMYHSVCQRYLKQK--KFDALELLHQGAKNMLEHDQLGSAEDLAQRMM-DIYDSERVVDLFQDDQYVRMCLRWSAKH-SACPAGDPLMHHAFGSRYYKEAEYHFIYGTTDSAKALGHMIGYFIARAVLQSLKIHHANIFIKDLSLINFTQFLLLCVQRLKNQYHMVDKIGEVFFGLLEDMM Sporo1 -------------------------------------------------MLIEDVYKARKIIQLIALKTLTDAVFAWTAKT-GSGPAGDVEIHQYLGETMHKEATLHLLVPTQSAARTLADVLGRYAARGTLSYLFILAARTFLSLAASLNFLQLAVRAAQALVTRYESIAALGEIYFGILMDMM Stehi1 YEAHQKARTFASRYQKSS--QYDAIDVLFQSARELLKAGQQGSGTDLTVFLL-DVYDAKRLTQLIALKTIIDKSVVWSAKH-GIYPAGDPDLHHYIGELLYKETESHLLAGKRDSARVLAHVYGSFGLRGTIPYLNILAARIFLQLLTALNFVQLAVRTCQRLCGTYQALNEIATVYFAIFGDIM Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 YSAHQKALTTTARLVHSD--HVNALDILFATARELLKLGEAASGVELGVRMT-QIMTEGSLTQLLALKKLVDAAIRWTQVK-GTCPTGDPGLHQYVGEMNYKDAEHHLLAGKRDAAITLAEMMSPYALRGTLPFLSILPALTFL-NLPTLNFLQLALLTVQRLVGRYEVMDKIGQEVFLILQNLM Trire2 YEAQQQTRVAASRYIKAQ--NWPAIDVLYSVAQSLLKAAQGGSGGDLCVMMV-DVYKQARLLTCLRLKKFIAESMGWSSKF-GEYPAGDPELHHVAGSLYAEEAERHLILGTKDSPEVLLKMEPHFAARAILPYLNVRAANTFISALPLLNFLGLLLLAIQRLVSKYEPLEMIGEMYFGILMDMM Umbra1 YEAHQMYRTVARRYTKQE--KYRVIELVHSGAVSLMKAKQSGSGSDLAMYMI-ETYKLARVAELLELKPFINNAMNWSQKN-GDNEMGDAELHNFVGTIQYYEAEKHLLFGTEESAQLLGDLEGVFIARAVMQLLNIHYANLFAKRLSLINFSQLLILTAQRLKSKYEALSDFGLVFFNILQDLM Ustma22 YELHQKLRTKTVRQVKKK--QYDAISTLHQGALELLSQSEQGSGCDLAVYMI-DVYGIKRITDILSKKKVIDAAVKWSVKA-SGASTGDPLLRLFIAKLYAHEAEPHFLAAVESAPKAYAQAMGRFALRATIPLLAVKAATTYLSTVADLNFSQIAVALVCELVRQYAAIPQIGTDWFGLLSDMM Walse1 YSAHQRVRTISTRLSKNG-----SIELLFTVSKSLLEKSEWGSAIDCSILML-----NQLVTQLISLKKLIDNAITTSATS-FKIPSGHPDLLDFIGNLYYKEAEYYLILSKKESAVTLAKLYGRYALRGVLAFIQVEAAITFLIQLHTLNFAQFIIASIQRLVSHFQACTEIGSLYFDIMMDIM Zygro1 YEAHQTLRTIANRYVRSK--SYQAIDLITQGALSFLKADQGGSGTDLIFYLL-EVYDLARLVQLLVAKDVITGMNNWSIKY-SEFKFGDPSLHNVIGSKYIEGAERYLMLGTHDSLLKYVDLLGDYFSRLVFNYLNVAWAYEFLQLFADLNFLQLLLLTCQTLKEHYNELEFLGQEYFGILQDMM [Cluster2536.fasta_al_trimmed; alignment length = 244] Allma1 ----------TYGK-QFDRVS-TKN-AVPLNVTTMADPVIHELAVYATDAILAQIMAAPRSVYSWDVIVTRVGDNAVYLDSRPNELQSVNENATNSAANLAVEATAINAHYAQHVVDAFVYRKFILLVVRTELDAA-LRALNQDWRKA-LDAQRGAVVATEVRNNANKVARWTLQALLADADVLKIGYVTRAAARDPSKHVLMGAAPAEFAAQLSLQLENAWGIVETVVQKYLLMKDPNKSALK Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 PDWTMLEEVDYYDR-SYDKAP-VKNAERKLNVTTSQDPVIQELAVFATSDILSMLMCAPRSVYSWDIVIVHQGD-KIYFDKREGDLVTVNENAINTPSALALEATFINHNFALQTVVEYKYRRFDLMIVRTEVDALIVKALNEDWRSK-LWSQRGAVVATEMKNNSIKLARWTTQAILAKADAMKLGFVSRANPRSATSHVILGVKPREFAAQMNLNLGNGWGIVRTIVDKYVLIKDPNRPVIR Aurde31 PNWKMLEEIEPYDK-AYDRVT-TKL-EKPLNPTTSDDPILREFAIYTTDSILSLLMCAPRSVYSWDIVINREGD-KLFLDKRDGDFLTVNENAINSAISLALEATYVNQNFTFQAVKEFRYRLFDLIAVRTDVDAVNIRALNEDWRTK-LDAQRGAVVATEMKNNSCKLARWAVSSVLAGADILKLGYISRVNPRDNARHVVLSTRPSDFAAQLNVSIANGWGIVRGIADKYVLVRDPNRPVVR Batde5 PNWDVVEELDYIDK-AYERIS-SKN-EKPLNVTAFDDPVLQNLAIITTSSVLAALMASTRSINSFDIIVTKKKN-IVYLDKRDGDLPTVNENAINSPLALAHEAGDIVRSYSQQVLREYRYRQWQLLIARTQIDAATIRSLNESWRQK-LDSQRGAVVATELKNNANKLCRWTIESLLASADQIRLGFVSRSNPRDRKRHGILGSKPDDLATHIHLNVGAGWGLVKAFGDKYLLMRDPNKPVLK Botbo1 PSWQMLEEIDAYDK-TFDRIN-TRM-ERPLNPTTTDDPVIQQLAIYTTDNILSLLMCAPRSAQPWDIVIIREGD-HLYLDKRDGDFISVNENAINSQSSLALEATYVDQHFSFQAVKEYRYRLFDLVAVRTQVDAITLKTLNEDWRTK-LDSQRGAVVATEMKNNSCKLAKWAVQSVLAGAEMMKIGYVSRANFRDNTRHVILSTRPIDFAGQLNVSLSNGWGIVRTVADKYLLVKDPNRPVIR Botci1 PDWKMLEEIDYYDR-SFDKQP-VKAAERKLNVTTSSDPVIQELAIFATDSILSMLMCSPRSVYPWDIVIVRQGN-KVFLDKRDNDMVTVNENAINQPSALAEEATYINHNFANQVMKEYKYRKFDLLVVRTELDALTVKALNEDWRTK-LVSQRGAVVATEMKNNSCKLARWTVQSIIAKADVMKLGFVSRANPKLNDRHVVLGVKPRDFASQMNLSLSNGWGIVRTIVDKYVLVKDPNKPILR Caeel PEWVVLEEMNYYDK-TIDRVS-VKN-SIPLNVTTTEDPVIQELAVFGTDIILATLMTAPRSVYSWDIVAYRVGD-KLFFDKRNTETLTVSETSINNAKDLATEAFYINQNFRRQVVKRYKYRKWNLLVCRTELDGLTIKAFNEDWRTK-LDVQKGAVMATEIKNNSAKVAKWTLQALLAGSDTMKLGYVSRNNARSTQNHSILLTKPTEFASNIALNMDNCWGILRCVIDKYLLMKDPQSPVIR Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow PEWKLLEEIDVFDR-AFDTLT-TKS-DKALRVTAIDDPVLREHAVFATDNVIAAIMSCTRSVYSFDIVVEKIGD-KLFLYQRDNDFLTVDETSINAPRKLAVEATLVNQYFTQQVLKKYRYRRWNILVCRCEVDGVMVKALTEDWRQK-LDIQRGALLATALKNNLFKVCRWAAAASLSGASQIRVGFVSRASPRDNTRHTVLGTRPKELAQQINFQLSNGWAVLRTVIDKYLLLKDPSKRSIV Catan2 PEWSVVGELDTYSK-VFDRVS-TKN-EMALSPSTLEDPVLIELVIFATDAILSQIMMAPRAVYSWDLVVTRLGEHVIVLDKRPGDLASVNENAPNNPGNIAIEATYINANYSQQVVDHYMYKKYSFVIVRTEVDAATVRALNQDWRKA-LDSQRGAVMATEMRNNTYKLARWITQALLAETDVLKVGFVARAAPRDVSRHTILGVKPQEFATQMNLSMTQGFGVVYALMEKYVLLKDPNRQFLK Cioin ETWEVLEEMDSYDR-AYDRVS-VKA-EKPLKVTTTDDPIIRKLAVYATDAILATLMCCTRSQYSWDIIAQRVGKNKLFFDKRDDDLLTVSETAMNSPHNLAMEATYINHNFSQQVLKQYRYRKWNLLVSRTEHDAINVKALNEEWRRK-LDSQRGSVLATELKNNSSKLAKWTMCALLAGSEYLKMGYVSRYNIQDSSKHVVIGTIPKEFASQINLSVANAWGILRCIIDKYLILKDPNKPVIR CocheC53 PEWSVMEEIDYYDR-SYDKQPGAKTSERRLNVTTSSDPVLQELAVFATDNILSMLMCATKSVYSWDLVFTKRDN-KVFIDKRDGDMVTVNENAINSPGALMLEATHINNVFPLQVVTEYRYRRFDLLIVRTELDALTIKALNEDWRTK-LASQRGAVLATEMKNNSCKLARWTVQSILAKADTMKLGFVSRANPKNNNDHVILGVKPRDFAAQMALNLNNGWAIVRTIVDKYVLVKDPNKPLLR Coere1 DDWELVQEIEIYDH-LYDRVN-TKL-ERPLNVTASQDPVLNNLAVFATDTVIATLMASMVSTGAWDVVVNRVGD-RLFFDKRDGDFPSVNENAINSAAMLAGEARDVNRSYISQITSKYRYRILDFMAIRTEISGLFLRALTQDWRQK-LDSQRGAVIATEMKNNASKLARWAFQAVLADADQLRIGFVARTTPRDRSRHGVLGFNPSDFVQQLSLSEYKAWGIVKALVDKYVIMRDPNKPLIL Conco1 SDWKVLEEIDYYDR-KFDRP--TKS-TGKLNVTTSEDPVMQQLSVYITDAILSLLFCAPRSVYPWDIVINRVGD-HVFFDKRDGDFISVNENSINSVSALSEEATLINQYFASQVLDRYKYRAYELVVVRGEVDAMKLCALNEDWRQK-LESSRGAVVATEMKNNNCKLARWAIQGVLGGAEQLKLGWVSRTKPKDNTNHELLATKPKDFLTQLNFKFTNGWAILRALSLKYILVKDPNTAIIR Conpu1 PSWQMLEEIEPYDK-SYDRIT-TKT-EKPLNTTTSDDPVIQQLAVYTTDVILSVLMTAPRSVYPWDIVIIREGD-NLFLDKRDGDHVTVNENAINSATDLSLEATYISQNFGFQSVVEYRYRVFDLLCVRTEVDAITIRALNEDWRSK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGAELMKLGYISRVNPRDNSRHVILSTRPTDFAAQLNVSFANGWGIVRTVTDKYVLVKDPNKSVIR Copci PSWQVLEEIEAYDK-TYDRIT-TKT-ERPLNPTTSDDPVVQQLVVYTTDIILSVLMCAPRSVYPWDIVIVREGN-NLFFDKRDGDTVTVNENAINTATSLSLEATYINQNFGFQTVIEYRYRLFDLLCVRTEVDAVTIRALNEDWRTK-LDSQRGAVVATEMKNNSCKLAKWTVQSILAGADLMKIGYVSRANPRDNTRHVVLSTRPTDFAAQLNVSLANGWGIVRTIIDKYVLVKDPNKPVIR Croqu1 PDWQVREEIEEYDR-IYDRIN-TKN-PQPLHPTASDDPVMQELAVFTTDSVLSLLMCATRSVYPWDIVMIKEGD-KLFMDKREGDFVSVNENALNTPSALSLEATFINQNFGLQVVKELRYRKFDLLIVRAEVDAITIRTLNENWRAK-LDSQRGAVVATEMKNNSCKLAKWAVQSILAGADQMKMGYISRANPRDASRHVILGQRPKDFASQINVNLANGWGIVRTFVDKYLLMKDPNKPVVR CryneH991 PEWEVLEEIDAYDK-TFDRIN-TRN-EKPLNPSTSDDPIISQYAIFATDSILAVLMCAGRSVNSWDIILEHRNG-QVFFDKRESDYITVNENAINSAGSLSLEATYISHNFSSQVSANYKYRKFDLVILRTEADAVTVKALNEDWRKN-LDTQKGAILASEMKNNSAKFARWATQSILAGVEQMKMGYISRANPRDAQRHTIVGVKPVDFARQMNVSLANGWGIVRTIADKFVLVKDPNNPLVR Crypa2 PDWKLLEEIDYYDR-SYDKQP-VKTAEKKLNVTTSSDPVIQELAIFATDSVLSMLMCAPRSVYPWDIVIVKQGN-KVFLDKRDNDMVTVNENAINQPAALAEEATYINHNFANQVVLEYKYRKFDLLVVRAEIDALTVHALNEDWRSK-LVSQRGAVVATEMKNNSCKLARWTVQSILAKADAMKIGFVSRANPKANDKHVILGVKPRDFANQMNLSLSNGWGIVRTICDKYVLVKDPNKSILR Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 SDWPLVSEIEVYNK-KFELFR-----PEPMHHPATKDPVLQKLAVFATDSVLAQLMCAVRSAYSWDIIVTKRNG-SIYFDRRPGDRIEVDENSIDSATNLSEEATAVNRSFIASSITTYKYVKYSLVFVRSQADAVSVNALTQDWKTKSVTGSRGVIFASELKKNNNRIARWTAQAMLGDLDALKIGFVSRKIPTNNTKHVVVGAAPAVLSAQIRLSMGNGWGIIKSSIDKFLIFRAPGIPKLS Dicdi SSWESKEEFDYYNK-VYDRIN-AKN-EKKLLIPTSDDKVIRSEYVYATDSILAVLMSAQKSVYSWDIVVQKVGA-RLFFELRPGEHLTVNENLINTTSSLSQEATQVNLNYWQQVLSQYAYKKWDLVLARTEIDGISIKAINEEFRKK-LDSQRAAILATEIKNNSTKFAKWSIQSTLAGCEMLNLGFVSRDSIRDNNNHVILGTPVADLNKQNGVDMKNCWGILKHIAQKYLLHRDPNRNVIN Dmel ADWASIEEMDYYDK-TYDRIN-VKN-EKPLTVTTTDDPVIRRLSVFATDAILATIMCSTRSNYSWDIVIEKVGD-KVFMDKRDHDLLTVNESSCNSPRNLAIEATFINHNFSQQVLKTYRYKKWELLVARCEHDGMTIKALNEEWRQK-LDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTKPHEFATQINLSMDNAWGILRCIIDKYLIMKDPNKPIIR Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba DSFRPVTTFEQYVS-AQDGVT-TKK-AKALNVMASSDAIIKELAVFTTSSVLALLMSTPRSVYSWDLVIRRQGG-KIFIDKRDGDFYTVCESAVNSPASLSMEATRLNASFPQLSVTDLLYRSVPLMVVRSDVDAINIRALNENWRSR-LDAQRGAVMAVELKFNAHKLARWASEAHLAGSDLLKIGFVSRTAPRDPSRHTLLGTSPESLASQVNLKLENSWAIVKAVCDEYLLMREPNKPALG Fomme1 PSWAMLEEIEPYDK-TYDRIT-TKT-ERPLNTTTSDDPVIQQLAIYTTDVILSVLMCAPRSVYPWDIVIVREGN-KLFLDKRDGDTVTVNENAINTANSLSLEATYINQNFGFQSVIEYRYRVFDMICVRTEVDAATIRALNEDWRSK-LDSQRGAVVATEMKNNNCKLAKWTVQSVLAGAEVLKIGYVSRLNPRDNTRHVILSTRPMEFAGQLNISLANGWGIVRTVTDKYVLVKDPNRPVIR Fusgr1 AEWKLLEEIDPYDR-SYDKQP-VKGAEKKLNVTTSSDPVIQELAIFATDSILSMLMCSPRSVYPWDIVISRQGN-KIFLDKRDNDMVTVNENAINQPNALAEEATYINHNFTNQVVVEYKYRRFDLLIVRTEVDAISIHALNEDWRSK-LVTQRGAVVATEMKNNSCKLARWTVQSILASADVMKLGFVSRVTPRSNDKHVVLGVKPRDFANQMNLSLNNGWGIVRTIADKFVLVKDPNKSILR Galma1 PQWSMLEEVEAYDK-SYDRVT-TKT-EKPLNTTTSDDPVIQHLAVYTTDAILSVLMTAPRSVYPWDIVIVREGD-SLFLDKRDGDTVTVNENAINTATSLSLEATYINQNFGFQSVIEYRYRLFDLICVRTEVDAVTIRALNEDWRSK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGADLMKVGYISRANPRDNTRHVILSTRPTDFAAQLNVSLANGWGIVRTVTDKYVLVKDPNKPVIR Ganpr1 PEWKVRDEYDYYDKFTFDRIT-VKN-PKPVRVTASQDTIFQSMAVFTTDTVLSTLMCATRSAFSWDIVVVKDGD-KMWLDKRPGDFVTVNENAENTASALAAEATQVQKDLLALVTKELRYRTFHLLAVRTTLDAVSVKALLEEWKKR-LDAHRGTVVATEIKNNGNRMAKWAVEAVLAGAGQIRIGFVSRTSPRSSKSHVLLSMKPKEFAGQMNLSLNNAWGVVRTIIDKYVLVRDPNKPVIR Gloin1 TTWNTPGDVEYYDK-NYDLIR-TKS-EKPLFDSTSKDPIIDQLAVFATDSVLSLLMCAPRSVYPWDIIINRVEN-KLFFDKR------------------------------VYVVNEYRYRKFDIIVVRTQLDSITIRALNEDWRQK-LDTQRGAVVTTEMKNNSCKLARWAVQSILAGADQMKLGYISRVSPKDNTKHAILGTKPRDFAAQMNLSVSNGWGIVRTVIDKYVLIKDPNKPVIR Hisca1 TEWNMREEIDYYDR-TYDKPP-VRNTERKLNVTTTADPIIQELAVFATADILSMLMCAPRSVYSWDIVIIQQGN-KIYFDKRDNDLVTVNENAINTPGALAIEATVINHNFALQTVIEYKYRRFDLLIVRTEVDALTIKALNEDWRTK-LVSQRGAVVATEMKNNSCKLARWATQAILAKADMMKLGFVSRANPKSASAHIILGVKPREFAAQMNLNLSNGWGIVRTIVDKFVLVKDPNKPVIR Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 PQWSMLEEIEAYDK-TYDRVT-TKT-EKPLNPTTSDDPVIQQLVVYTTDIILSVLMCAPRSVYPWDIVIVREGN-KLFLDKRDGDTVTVNENAINTATSLSLEATYINQNFGFQSVIEYRYRLFDLICVRTEVDAVTIRALNEDWRSK-LDSQRGAVVATEMKNNSCKLAKWAVQSVLAGADLMKIGYISRANPRDNTRHVILSTRPTEFAAQLNVSLANGWGIVRTVTDKYVLVKDPNRPVIR Lenti61 PDWAMLEEVEPYEK-SYDRIT-TRT-EKPLNPTTSDDPVIQEMAIYTTDVILSVLMTAPRSVYPWDIVVVREGN-KLFFDKRDGDTVTVNENAINSATSLSLEATYINQNFSFQAVIEYRYRVFDLICVRTEVDAVTIRALNEDWRTK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGADHLKIGWISRVNPRDNTRHVVLSTRPADFAAQLNVSLANGWGIVRTVADKYVLVKDPNKPVLR Malgl1 PDWEAMGDLDQYDR-SYDRVS-VRF-ERQLNPTTSEDPVIQDMAVYMTDSILALLMCAPRSVYPWDIVITKSDDGTLFFDKRANDFLTVNENAINTPGTLSLEATFVNENFGFQVCDEYRYRRFNLMVVRTELNAITIRTLNEDWRSR-LDQSRGAVVATEMKNNSFKLARFAVQSILAGADNMKLGYISRLNPLDPYRHTILGTKPRELAAQMAYSLPNGWGIVRTIIDRFVLAKDPNKQVVR Mellp23 PEWQVREEIEEYDR-VYDRIN-TKN-PQPLHPTASEDPVIQDLAVFTTDSVLSLLMCATRSVYPWDIVMIKEGD-KLFMDKREGDFLSVNENALNTPSALSLEATFINQNFGLQVVKELRYRKFDLIIIRAEVDAITIRTLNENWRTK-LDSQRGAVVATEMKNNSCKLAKWAVQSILAGADQMKMGYISRANPRDASRHVILGQKPKDFASQINVNLANGWGIVRTFVDKYLLMKDPNKPVVR Mnele KDWELQVEIEHYDK-RYDRIT-TKA-ERPLYVSTTDDPIIRELAVFATDSILATIMTCPRSYYSWDIIIQRVGS-RLFFDKRDDDLLTVNETASNSLQKLSLEATYINQNFSQQCLKRYRYRKIPLLICRTEVDAMNIKALNEEWRQK-LDTQRGDILTTEMKNNKCKLAKWTVSSILAGSDLLKFGYVTRSMPRSSGEHSILGTIPKQFAGQISLDMNNAWGILRVIVDKYVLYKEPGKGILR Monbr PSWELLEDIEFLDQ-AKEKTVPKRPVEVPPSVPASEDPVLQKIDVFATDDVLATFMAATRSHYSWDIVATKKDG-KIYFDKRPGDMLSVDETAPNAPGNLSVEATHVNQMFKDFAVNKYRYRVWDLLAARTQHDACSVNTLLEDWRTV-LASQKTAVLASQLKDNAFKLARWTICSLLGNNSTMRLGYVSRANPASPRKHVLLKVRTEKFAEQIGVNMANGWGIVKSMIVQYVLMKDPGEPMLK Morel2 AEWNMLEEIETYDK-AYDRVN-TKQ-EKVLNVTTSDDPILTNLAVFATDSIIGVLMTAPRSVYPWDIVITRTGD-KVVFDTREGDYVSVNENSINSPAALSLEATYINTNFAAQVVNSYRYRKFDLLIIRTEVDAITLKALNEEWRQK-LDSQRGAVVATEMKNNSCKLARWVVQSMLAGADHLKLGFVSRTNPKDAARHAILGTRPKEFASQMSLQVTNGWGIVKTVVDKYVLVKDPNKPVIR Mucci2 ADWKVLDEIEVYNK-AYDRVN-TKN-EKMLDTTTSEDPIIQQYIVFATDAVLSLLMCATRTVYPWDIVVKKTADGKVILDKRPGDFVTVNENSINSWSALCNEATYINQNFSRQVLEKYRYREFDLMIVRTEVDAVTVRALNEPWKKS-LDSQRGAVVATEMRNNAAKLARWAVQALLADAEQLKLGYVARYNPKENSRHVILGTKPRDFASQMNLSLTNGWGIVKAVVDTYIMMKDPNRPILR Mydma DNWRVIEEMDYYDK-MYDRIS-TKN-ERLLRVTTTDDPIIRKLAVFGTDAIISTLMCCTRSVHPWDIIVHRVGK-KLFFDKRDDDLLPVYETTINSPANLAVEATYINQNFTQQCLKKYRYRKFSLVVIRCEHDALNIKTLNEDWRQK-LDSQTGSCLATELKNNSNKMAKWTCNAILAGSDTLKFGYVSRVALNDASRHVILGTKPKAFAQQIVLDMDNAWGILRCIVDKYLLLKDPNRGVLL Neucr2 GDWKLIEEIDAYDR-SYDKPV-VKNAERRLNVTTSSDPVIQELAIFATDNILSMLMCAPRSVAPWDIVISRQGN-KIFFDKRDNDLVTVNENAINQPHALAEEATFINHNFANQVVVEYKYRRFDLLVVRTEIDAVTVHALNEDWRTK-LASQRGAVVATEMKNNSCKLARWTVQSILAKADVMKLGFVSRVNPKVNDKHVILGVKPKDFANQMNLQLSNGWGIVRTIADKFVLVKDPNKNILR Orpsp11 DQWKVIEDIDYYDQ-AVDRIS-AKS-GVALNPSTADDEVIQSIAVFATDSIISTLMCAPRSVYPWDIVITKCGE-QIFFDKRDDDYYTVNENAINSSSQLSEETTRNCKCFAEQSVDKFRYRKWALLIVRTTLDALNVRTVDESWRKS-LDNQKVGCITSEFRSNFNKLSKWAVESILSGADYIKFGFISRVNNKDNKRHEILGTKPREFANHLQLTIENSWGILKEVVDKFVLVKDAVK-VIK Pench1 PDWKMLEEVDYYDK-SYDKPP-VKNAERRMNVTTSQDPVINELSVFATSDILSMLMCATRSVYSWDIVIVHQGD-KIYFDKRDGDMVSVNENAINTPNALAMEATIINHNFALQTLIEYKYRRFDIMVVRTEVDALIIKALNEDWRSK-LNSQRGAVLATEMKNNSAKLARWTTQAILAKADGMKLGFVSRVNPRSAAAHVVLGVKPREFASQMNLNLGNGWGIVRTIVDKYVLIKDPNKSVLR Phybl2 ADWKVLDEIEYYNK-AYDRVN-TKN-EKMLDTTTSEDPIIQQFIVFASDTVLSLLMCATRTVYPWDIVVKKVGN-KVILDKRPGDFVTVNENTINSWSSLCTEATYINNNFARQVVDQYRYREFDLMIVRTEVDAMTVRALNESWKKS-LDSARGAVVATEMKNNAAKLARWAVQAMLAGSDQLKLGYVARMNPKDNTRHVVLGTKPKDFASQMNLSLNNGWGIVKAVVDVYVLMKDPNRPMLR Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 PQWQMHEEIEAYDK-SYDRIT-TKT-EKPLNTTTSDDPVIQQLAVYTTDVILSVLMCAPRSVYPWDIVIIREGN-SLYFDKRDGDTVTVNENAINAATSLSLEATYINQNFGFQSVVEYRYRVFDLICVRTEVDAVTIRALNEDWRSK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGADLMKIGYISRANPRDNTRHVILSTRPTDFAAQLNVSLANGWGIVRTVTDKYVLVKDPNKPVIR Polpo ADWELKEEIDYYNK-DIERVN-ARD-ERKLLISTSDDKVIRTNFVYATDEIMSTLMTANRSVYSWDIVVIRIGG-KIFFEHRPGNTLTVNETSVNSASALSNEAAEVNINYWQQVLT-YRYMKWNLVLARTEVDGVSIKATNEDFRKN-IDNQRASVLANEMKNNSTKFAKWSIQSTLAGVETMNLGYVSRYYQGDPTNHVVLASSVSSLNSQNRVDMRNTWGIFKRIVQKYLLHRDPNRAVVN Pucgr2 QDWQVLEEIEEYDR-TYDRIN-TKN-PQPLHPTASEDPIIQELAVFTTDSVLSLLMCATRSVYPWDIVIIKEGG-KLFLDKREGDFLSVNENAPNTPSALSLEATFINQNFGLQVVKELRYRSFDLLIIRTEVDAITIRTLNENWRAK-LDTQRGAVVATEMKNNSCKLAKWAVQSILAGADQMKMGYISRANPRDASRHVILGQKPKDFAAQINVNLSNGWGIVRTAIDKYLLMKDPNKPVVR Punst1 PEWAMLEEIEAYDK-SYDRIN-TKN-EKPLNTTTSDDPVIQQLAVYTTDVILSVLMTAPRSVYPWDIVIVREGN-KLYFDKRDGDTVTVNENAMNSATSLSLEATYINQNFAFQAVAEYRYRVYDMICVRTEVDAVTIRALNEDWRSK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGADTMKIGYISRANPRDNTRHVILSTRPADFAAQLNVSLANGWGIVRTVTDKYVLVKDPNKPVIR Rhior3 PDWKVLDEIEVYNR-AYDRVN-TKN-EKPLDTMTSEDPVIQQYIVFATDVVLALLMCATRTVYPWDVIVKKTSDGKVILDKRPGDFITVNENSINSWSALCNEATYINQNFSRQVVDQYRYRSFNMMIVRTEVDAVTVRALNEPWKKS-LDSQRGAVVATEMRNNAAKLARWAVQSILAGAEQLKLGYVARANPKDNSRHVILGTKPRDFAAQMNLSLTNGWGIVKAVVDTYIMMKDPNRPILR Rhoto1 NDWVSLEEIEEYDR-TYDRVN-TKN-EKPLNPTTSDDPVMQELAVFVTDNILSMLMCAQRSVYPWDMVLTREGD-KLFIDKREGDYPSVNENALNSPSALSLEATYINQNFAFQVVREFRYRRFDILVVRTEVDAITIKTLNEDWRTK-LDSQRGAVVATEMKNNSSKLARWAVQSVLAGAEQMKMGYVSRANPRDASRHTILGTKPRDFATQMNINLANGWGIVRTIADKYVLMKDPNKPLIK Rozal11 PKWELLMEFEKFDG-TFDKIS-IKNPKQLL-PSVVEDPTMADFIIYTTDNILSALMSHCRSTIPFDFKIIRKDD-YVIIDAREGNFETLLESTYNSPLSLIDEVTKCHHKFSAQV---INYRLWDFLLCRTSLDAVSTHCLVEDFKQK-ADSQRGAILGSEMLNNPNKLARWLFQSILADAKFLKIGYVSRKLSRDNTKHVILGTAVDDFAVQIHMDVYNGWGTVKALSDEYVMVRTPRKGGLR Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro AHWDIIRELEVYNP-GLNTIR-PKT-AKRLALTTSADPVMKTFMVFITDDILAAIMVAARSFYSWDVIVHKEGE-RLVFDKREKDYLTVNENGPNHQLNLNREATFVNQHFQEQCWSKYRYRLWDLMLVRCTHDAASLCSINE-WRSR-LESQKGAVWAAALKDNSCKISRWVVQAMLAGNRELKMGFVSRASPNSATKHEILTVATAKLAKQLAINMQNGWGIVRSLVDDYLIFKDPLKEILK Schco3 PSWQVLEEIEAYDK-TYDRIT-TKT-ERPLNTTTTDDPVIQQLAVYATDVILAVLMTAPRSVYPWDIVIVREGN-NLFFDKRDGDTVTVNENAINTATSLSLEATYINQNFGFQSVNEYRYRVFDMICVRTEVDAATIRALNEDWRTK-LDSQRGAVVATEMKNNSAKLAKWAVQSILAGADLLKIGYVSRANPRDNSRHVILSTRPTDFAGQLNVSLANGWGIIRTVTDKYVLVKDPNKPMIR Schpo1 DDWQLLDEVEPYDK-SFDKIH-VKS-EKPLNPTTTEDPVIQKLAIFITDSILSLLMCSTRSVYPWDIVITHQSG-KLFFDKREGDYLTVNENAVNSPGALSVEATYINQNFCVQALREYIYRDVDLLMVRTEVDGISIKALNEDWRSK-LESQRGAVFATEMKNNSCKLARWTVEALLAGVDSMKVGFVSRSNARDAQHHGILGVKPADLASQMNLSLSNGWGIVRTIADKYVLVKDPNRPILR Sorma GDWKLIEEIDAYDR-SYDKPV-VKNAERRLNVTASSDPVIQELAIFATDSTLSMLMCSPRSVAPWDIVISRQGN-KVFFDKRDNDLVTVNENAINQPHALAEEATFINHNFANQVVVEYKYRRFDLLVVRTEIDAVTVHALNEDWRTK-LVSQRGAVVATEMKNNSCKLARWTVQSILAKADVMKLGFVSRVNPKVNDKHVILGVKPKDFANQMNLSLSNGWGIVRTIADKFVLVKDPNKNILR Sphar STWEVQDEIERYDK-SYDRVT-TKN-SKPLNVTTTDDPVFRDLAVFATDAIIATIMATPRSVHSWDIVVQRVGD-KLFLDKRDNDFLTVNETAMNTPSQLAIEATYINQNFSQQVLKSYRYRKWDLLVARCEVDALMIKALNEDWRQK-LDSQKGAVLAMELKNNSMKLAKWTACALLAGADTLKLG--------------------------------------------------------- Spipu1 PEWKVIEELDYYDK-TFDRIN-TKQ-EKPLNVTASDDPVLVSHAVYSTDNVLATLMCATRAVYSWDIIVNKQDN-KLFFDKRDGDFVSVNENAINTPQALAMEATYINRNFSQQALRDYRYRQWSLLVARTQIDAVNVKALNEDWRQK-LDSQRGAVMATEIKNNGNKLARWAMESILSGADQLRLGFVSRVNPKDRNRHTILGTKPRDLTSQMNFNVGNGWGILKMFVDKYVLVKDPNKPLLR Sporo1 SDWQQLEEIEEYDR-VFDRVN-TKS-EKPLNPSTSDDPVIQDLAVFVTDSIISMLMVAGRSVYPWDIVLTREGD-KLFMDKREGDYPSVNENALNSPSALSLEATYINQNFAFQVVREFRYRKFDLIVVRTEVDAVTIKTLNEDWRTK-LDSQRGAVVATEMKNNSSKLARWAVQSVLAGADQLKIGWVSRATPRDASRHVILGTKPRDFASQNNVNFANGWGIVRTIADKYVLLKDPNKPLIK Stehi1 PSWQMLEEIEAYNK-TFDRIT-TKT-ERPLNTTTSDDPVIQQLAVYATDVILSVLMCAPRSVIPWDIVIVREGD-KVFLDKRDGDTVTVNENAINSATSLSLEATYINQNFSFQSVTEYRYRLYDLLCVRTEVDATTIRALNEDWRLK-LDSQRGAVVATEMKNNSCKLAKWTVQSVLAGAEQMKIGYVSRANPRDNTRHVILSTRPTDFAAQLNVSLANGWGIVRTVTDKYVLVKDPNKPVIR Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr EEWEQVDSIPPFNA-ALRGVD-TRN-PLKLNVSTTDDPIIQSLAVFMTDDILAALMCASRSVDPWDLVVKRIGD-YVFFDKRDGDFLRVRETAINAPEPLSREATLINQYYSQQALDVYTYRKFEYFVVRTQVDAMTVHALHENWRSS-LDTQGGAVLATEIKNSANRLARVTARAIAAGNDLVHLGFVTRTNPAKHIDHSVLGTRTETLARQLQIVPEALWVSAAAIVDTYVLMKDANESVLR Treme1 SEWRLLEEIDPYDK-SYDRAN-TRN-EKPLNISTSDDPIIADMSIFATDSILAVLMCASRSVNSWDIILDRRGD-QLFFDKRPNDYITVNEHAINSPSSLSLEATYINQNFANQVIAEYRYRKFDLVVVRTEVDAITIKALNEDWRKH-LDTQRGAILATEIKNNNAKLARWSVQGILAGAEQMKMGYIARANTRDATRHVIVGVKPRDFAGQMNISLSNGWGIVRTIADKYVLVKDPNNPILR Trire2 ADWELLEEIDYYDR-SYDKQP-VKGSERKLNVTTSSDPVIQELAIFATDSILSMLMCSTRSVYPWDIVITRQGN-KIFLDKRDNDMVTVNENAINQPSALAEEATYINHNFANQVVLEYKYRRFDLLIVRTEVDALTIKALNEDWRTK-LVTQRGAVVTTEMKNNSCKLARWTTQSILSKSDVMKLGFVSRANPRSNDKHVILGVKPRDFANQMNLSLSNGWGIVRTIADKFVLVKDPNKAILR Umbra1 PEWSVLDEIEMYDK-SYDRIN-TRN-EKLLDTTTSDDPIMQQFMVFATDSILALLMCAPRTVYPWDIVITRVED-KVILDKRDGDFLTVNENTINSPGALSSEATFINSSFAAQVIDQYRYKSFDLLIVRTEVDALTVRALNESWRKA-LDSQRGAVVATEMKNNSAKLARWAVQALLAGAEQMKIGYVSRASPKDSSRHVVLGTKPRDFMAQMNLSMANGWGIVKAVVDKYVLVKDPNKAILR Ustma22 QDWEQVEEIDEYDR-SYDRVT-VKT-AQSLNTTTSEDPVIHDISIYMTDSILALLMCATRSVYSWDVIITKTADGKVFFDKRDGDYLTVNENAINTPSALSLEATYINQNFAFQVVNEYRYRKFNLLVVRTEVDAITIKSLNEDWRLK-LDSQRGAVVATEMKNNSFKLARFAVQSLLAGADSMKLGYISRANPKDTSRHMILGTKPRELAAQMAVNLSNGWGIVRTVADKYVLLKDPNKQTIR Walse1 PEWEKIAEIDPYDR-AFDRIT-TKN-EKPLNPTTSVDPVIQKLAVFATDSVLSVLMTSARSVYPWDLVVVRKGD-QIFLDKREGDFISVNENALNTPASLSFEATYVNHNYTTQVTNEYKYRKFDLLIVRTELDAITIKALNEDWRTK-LDSQRGAVVATEYKNNSVKLARWTVQSILAGAELMKFGFISRANPRDESKHVIVGVKPRDFATQLSINLSNGFGIVRTIVDKYILIKDPNRSIIR Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2537.fasta_al_trimmed; alignment length = 142] Allma1 QKLADKANSTLSTALRAACFDLVKTNMKAYDAT-DGWNDKAKRRELMRYLIV-----VAA--FAMFDFSIEEVLYW----------------------------PRHS---------------------------------- Ashgo11 AHAAAHAAAAARRRLAADLTALVAAGLAPYRAH-AAW-PRCKRAELALHILYRDPAGLAC--FISLLLPGPAVLYI--LELHVAAPFRRRGLAAALL-DAATRTLTRLELTVFTANRPALALY-ARAGF-----RPRI-MVC Aspfu1 VERTNSLPSTIPAEDFDACFKLIEQTSADYRAS-SGWSAARKRKEMMKYLIQRRSQ-ILA--FLSFMVTYEDVIYC--YEVHVAPKVQGQGIGMHLM-MLLRSILEKAMLTCFRSNRRALRFY-KSIGYKVDENSPRI-MSK Aurde31 VTEANKASSSLSPAHRTAVWRIFEENMRSYTAS-SGWDPPQKKRELSRFILAHS---LAA--FTMFRFDTEEVVYC--YELQVSSRTRKLGLGAALM-RDLESLMLKVMLTCFLTNVDAMAFY-KRVGFSVDPISPSI-LSK Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 VQLACKASSELSVPLRQKIWALFEENMHGTSST-TEWNPPSKKKELSRYLCVSSQ--LVA--FTMFRFDWEDVLYL--YELQVSQGYRKLGLGRVLI-RDLEAIMKKIMLTVLKANQGAILFY-DKMGFNLDPISPDI-LSK Botci1 IAIACAKSGTLCSQDLTACLELVEVTSGKYRES-RGWSGRRKRSEMLRYLVVREVG-IKG--FMSFMPTFEDVVYL--YEIHLMDELRGTGLGTHLM-SLLASIVEKTMLTCFTANEAALKFY-KKLGYEKDEYSPEI-LSK Caeel VKKACQ--THLSDEDFEWVFSLFKENMYDYHKS-QGYDENSKRNELSRFIIAKNSKGKIG--YTTYRFVVDHVAYC--WELQIVPAYQNKGIGGMML-DTLEKLMSKVMATVFLYNGPSLGFF-HKHGYNSDVTCPSI-LSK Canalb1 MEEIAEDL--MDENQIDKFIQLIDDNLGDYVES-ENWK-NNKKEEMLVYIWFTETTPLVG--FLSFKLCEDVVLYL--FEIHLTQKYQGQKLGQSLI-DQFHEFLQGTALTVFSNNTRALNWY-KKMNYELTEGSPML-MRR Cangl -------Y-KESKNILSSLLELLDQNLGQYEIS-SPWK-ENKIEEMMIYVSYWT---TVPLLFLSFMLTEEEVIFL--YEIQISKELRKQGLGQYFLSNCLFQ-FAGIELTVFADNLPAINLY-QKLGMTHTPESPKM-YWK Capow LREHQK--SELSKEDMEFCFNLTKTNMETYNAS-SGWSDQRKRTELARFLLARSQSSLVA--FVHFRFDFESVIYC--YEIQLSEPVQRKGLGKFMM-QIIELIMLKSMLTVFQANTSAIKFYRTILNYEIDEISPSI-LSK Catan2 RRTAASATRDIPDGLFDQCFALTKLNVGPYDAE-KGWNDDEKLADMQRFIVFTSDEQLVG--FLMYQFSTEEVGYC--YELQVAPGAQGRGIGSLLT-RMCIACMDKLMLTVFKANGSAIKFY-RNQGFSIDPTSPSI-MSI Cioin ---------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 --------TQLKEEDLQACIELVEQTSGDYRAS-RGWNTRKKREEMMIYLLRRKLD-ILG--FISFMFTWDDVVYI--YEIHLSPPLRHQGLGSRLM-TFVEAVIGKTMLTVFVANEGAKKMY-EKLGYQRDECSPVI-MSK Coere1 ---------------------------------------------------------------------------------------------------------------------------------------------- Conco1 --------------------------MKSYEQS-KGWNPRLKKRELMKYLIMFTKEDPVS--FISFKFDVEEVVYC--YEVQISQKFRSLGLGSFMM-NLIEELMEKLMLTVFTFNNRAISFY-ENIGFEIDPISPNI-MSK Conpu1 VNQANKASTTLSQSTREDIWNIFETNMRDYNSS-SGWDPPEKQAELSRFLVVHKSHSVEA--YAMFRFEREEVVYC--YELQVSPTARQLGLGKALM-QDLSRMMKKVMLTVFKANADACRFY-EHMGFTMDETSPGI-LSK Copci ----------------------------------SGYDPPAKRDEISRFILVYKSPLLVA--YSTFRFDREDVVYC--YELQVDEIMRGVGIGRKLM-GCLESVMDKVMLTNL-ANEKAFRFY-MQCGFKVDESSPSI-LSK Croqu1 --------------------------MKKYENR-SGYSPKEKRAELSRFLLALGP--LKG--FAMWRFDWEEVVYC--YELQVKESERGRGLGKELM-KLLEAIMKKVMLTVHLSNQPAVRFYTQKMKFEIDEISPSI-LSK CryneH991 --------------------------MRNQSNS-SPYTEMSKKEEMSRFLLALGETPLLG--FCEFRFDVEDVVYC--YELQLRPSVQKQGMARKLI-GILEDIMEKIMLTCLKNNASALSFY-RHQGFETDEIDPTI-LSK Crypa2 VKIAASKPCNTSDCDLDACFALVEETSRQYEAS-SGWNPKNKRKEMLRYILVK----LGG--FTSLMPTMEEVVYC--YEIHLRPELRRTGLAALLM-SFLQTVMEKVMLTVFTCNATALAFY-RRYGFEMDDISPRI-MSK Debha1 MKEISESVHKMPKDVLVECLLLVESNLKSYIKR-HGWK-SDKLKEMLIYVWYTD---LIG--FISFML-SYSVLYL--YEIHVAREYHSMKIGSQLI-DKLHEF-DGTSLTVFSDNSMALQWY-YKLGYQLTIDSPTL-LIR Dekbr2 IKSLEREQGSISTNELNACLDLIDHNLGAYARL-HTWK-MDKIKEMLIYILLKDNSTLAG--FLSMRILVDGVLYL--YEIQLDKAYQNNKIGSQAM-KHLSTILDGISLTVFSDNLGALKFY-QAQGYKFSKMSPRI-MIK Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------- Dmel VETAARAKSDADSKLLKWAFKLAETNVGPYKQL-KGWQPKIKAAELARYLVAQNEKKNVA--YAMFRFDMDHVLYC--YEMQVAAEYRRKGLGKFIM-STLEDCLEKVMLTVLNNNEASISFF-KQLGYVKDEISPDI-FSK Enthi LKMANELQKSIKKEQLQMCFELVKENMFSDSVS-SGWNDHDKMEEMGFYILFKE--------FVCIRFELFGGIQCYLWEIQIKKEYRRQGIGKEMM-NVIEIICSEISLLVLKSNVEGKAFY-DKLHF--------I-MRK Falba ---------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 --------------------------MKTYESS-DPWDPKQKQKQMARFLLITPDSQVLA--YAVFRFERDEVVYV--YELQTSGGSRRSGLGKALI-ENLESIMSGIMLTHIKLNAEAETFY-KSLNFKVDITSPDI-LWR Fusgr1 IEIANKVSTCMSGEDLEACYSLVDETSGAYRDS-SGWHPAAKKKEMLRYILVK----IKG--FTSFMPTFENVVYC--YEIHLKPELQGTGLGKQLM-GYYMDVIEKAMLTCFVSNKSALKFY-ERLGFTRDDYSPRI-LSR Galma1 VKLANKASNDLKQNQRDSIWAIFEANMYEYKNS-SGWDPVAKRKELSRFILLYQTDTLEA--FTMFRFEDEEVIYC--YDLQVTAFFQGMGLGKKML-SELGKLMEKIMLTVLKGNMKAALFY-KATGFSMDPSSPDI-LSK Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 --------TTLPTKLKEWAFDLLKSNMENYKGS-NGWNSKQKRQEMCKYLIASNNEK-IG--FAMFQFTWEEVIYC--YEIQLAEEARRKGLGTFLM-RTLENIMNKVMLTTFKKNKLAMDFYINRLGYQIDEISPSI-LSI Hisca1 VECVNALSTSISKTDLESCFLLVKLTSSEYKHS-TGWSPAKKKNEMMRYMLLVRNT-LGG--FLSFMVTYEDVLYC--YEIHLAPELQHRGLGKILL-GYYEEILQKTMLTVFKANGSAIRFY-ERLGYAEDEFSPKI-LSK Klula1 CQELNSTG-----STLPKCLAIIKQNLSTYELHGSKWI-RFKWDEMLVYIVLFKRDTIVG--FTSVALSDPLCLFL--YEIHLMGEYQSRGLGSLIFNGLLIPLCPSIELCVFTANDVACRWY-KRLGF--------IGMSR Lacbi2 VRSAIKAAEDLLESERNAIWMIFESNMRAYTSS-SGWDPRAKWKELSRFYLAYQAAALIG--FAMFRFEYEDVLYC--YDLQVTRIFQGTGLGKTLM-RQLAKIMEKVMLTVFKANTRAFQFY-NSTGFVVDSCSPSI-LSM Lenti61 LKQANKASSSLSESDCQDIWNIFETNMRSTERS-SGWDPKEKKEELSRFILVGHGDQLVA--YTMFRFEVGYSIYC--YELQVCDGFRGLGLGRFLV-DKLAIIMEKILLTVLKENIAAREAY-HKLGFQLDPNSPDI-LSR Malgl1 --------------MHERIFELLEQNMKAYDET-SSWDPWLKRDELSRFLLAFEDHELQG--FVMWRFDTDDVAYW----------------------------MLEMMIQ--------------------------I-VTR Mellp23 --------------------------MKQYESS-EGYSAQEKIKEMGKFLLVLG---VVG--FLIWRFDWEEVAYC--YELQFRKDACGNGLGRALM-NLLEEIMKKVMLTVHIANTRALSFYLNKMNYEFDEISPSI-MSK Mnele KEKKQQRKEQIDKETFEAIYRILEDNMKAYDAC-YGWNERDKRDEMPWFLIARNSEQIVA--FAHFKFDFDEVLYC--YEVQVTEDMRGKGVGKFLM-QILELIMQKIMITVFKHNPRAVHFFQDILKYTDDETSPKI-MSK Monbr -------------------MQLLDKNMSAYRAS-TGWSPTRKREELMCIARVMDSTALAG--FCTYLIDDEDVLYC--YELQVAATARGLGLGRRLL-QHMMSVVRFLMLTTFQAN-PSRGFF-ERCGLAIAPSSPDI-MRC Morel2 --------EDMTPALLTFAIDLVESNMSEYIKS-KGWCREDKEDEMSRYLIAFHNDK-VG--MVHFQFVDEEVAYC--FEIQVVPEYQRRGIGAYLI-SLLETIMEKVMLTVFKANKNAIKFYIDQMQYNYDEISPCI-LSK Mucci2 RPSHTKR-DDLPRELHEWAFQLVKTNLQDYEKS-KGWNEEEKRKEMARYLIARSATDIQG--FLHFQMVQEECAYC--YEIQIAESARGQGLGEYMM-NLLSQIMDKVMLTVFKANEGAFRFYIKKLG-------------- Mydma KEKKLKRQSAMESHEFDFAFEIVKDNMMAYQLS-SGWSEKKKREEMARYLLVKDHEEFLG--MAHFRFDVDNVLYC--YEIQLDDRIRGKGVGKFLM-QILELIMKKIVLTVFKDNLKGKHFFEK-LKYTSDETSPRI-YSK Neucr2 IERANRQTGKLSEEELKACFDLIKETSYDYQNS-KKWQPRKKMEEMLRYVLVK----IRA--FTSLMPTYEEVVYC--YEIHLKPELQGSGLGSLLM-GFHVTVITKVMLTCFLSNKRALGFY-KRHGFGTDDISPGI-MSK Orpsp11 SEEANKL-ENLPSPIFDKLFHILKSNMKKYQAA-NGWNQKKKIKEMARYLVVTTNNKIVG--FLYFQFSTEMVFYI--MEIQLIQKVRNIGIGRRLM-DIGEQWMERLMLTVFL---------------------------- Pench1 VEQTNALSSTISAADLEACLDLVEQTSSEYIAS-SGWSRTKKRKEMMKYLILRDTSNVLG--FLSFMVTYEDVVYC--YEIHLSPMARGRGVGKLLM-GRMEGILEKSMLTVFKSNEPARRFY-ERLGYEVDEYSPRI-LSK Phybl2 REERKKRRSQMTIELKEWAFNLVKSNLYHYRKS-NGWNALEKKAEMARYLIARSASDLYG--FLLFQMVTEEVAYC--YELQLVESARNYGLGEYFM-KLLAEIMDKMMLTVFKSNKGAFRFY-KKLGFELDEISPSI-LSK Picst3 MVHVLSEV--IQPELLLEFVDLVDTNLGKYVKH-SNWK-ENKRKEMLVYLWILD---LMG--FMSFKLCDEGVLYL--YEIHIVPQYKSLKYGGQLM-DVLHSICLATCLTVFTDNTMALQWY-LKLGYQLHPGSPQI-LFR Plicr1 VRAANKVDAALDDADRARVWEILEGNMRGYTNSTTSWDPPAKRAELSRFLLVRANDDIVA--YTMFRFEHEELLYC--YELQVAPSAQRTGLGAALV-AHLHALMEKIMLTVLKANEQAVAFY-ARLGFTMDPACPGI-LSR Polpo ---------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 --------------------------MKQYLKS-TGYKPKAKKRELSRFLLASGAHEIAG--FLMWRFDFEEVVYC--YEIQLKPETRGKGLGKGLM-EILERIMKKLMLTVQIENAKAINFY-RSLNFLPDEISPSI-LSK Punst1 --------------------------------------------------------------------------------------------------------MDKVMLTLIKANEHAAAFY-SALGFVEDPTSPGI-LSK Rhior3 ---------------------------------------------MARYLIARSSADLKG--FLLFQMVQEECAYC--YEIQLTTDARNQGLGEFLM-NLLSCIMDKVMLTVFKANKDAFRFYVEKLGFKLDEISPGL-LSK Rhoto1 VKLAKQATKGLSASLRDWIWALFEQNMRTYEHS-SGYDPAEKRQELSRFLILYSP--PVG--YCIFRFDTEEVAYC--YELQVDPAGQRKGVGRVLM-EALERIMDKTMLTVFKANRDAILFY-EKLGYTEDEVDPGI-MSK Rozal11 --------DNPNEELKSWMINLIEENARGYETS-EGWDRDKKLREIAKYLYVYHSDNPIG--FSHYRIEDEEVLYI--YEIHFMAQYTGKGFGSTLM-ENLEQLVSDLMLTVFKRNNYALSFY-KKRGFIKDELSPEI-LSK Sacce1 IDSVDSLK-SRGDQVLDACVQLIDKHLGAYRRA-SPWK-ANKLAEMLVYVCYW----VLGA-FTSFMLTEETVIYL--YEVHVASAHRGHGIGRRLLEHAL---FFGVALTVFSDNTRARRLY-EALGFYRAPGSPAV-YCL Salro VEQAAREEKVLQSPYLSDIWTMLDR-MRPYDKH--GWDWSEKEDELMHFILLLQQQQLIG--FTIFLLDEEDVVYC--YELHVAEGHKGKGLGKFLV-ECLEHVMVGIALTCFKDN-DALRFY-ERTGFSIADHSPSI-LMK Schco3 --------------------------MKDYMNS-SGWHPEQKLDELARFILVRRLRDVVA--YLSFRFDMEEVAYL--YEVHVCSSCRRQSLGRILT-DQIRRVMSSVMLTVFEANTPALKLY-ESLGFVLHPTSPGI-LYC Schpo1 TQEIKNVTHHLEKGLLQQCFNLVKKNMEAYRQS-SGWDDSEKLKEMLEYICIFEKTSLVG--FLSFEDTVEACLYI--YEIQLDEHIRGRNVGKWLL-KNASILLKYIFLTVFSANLNALNFY-HHFDFVPHESSPQI-LYT Sorma IERTNSKTDKLSKEELQACFDLVKETSYDYQNS-KKWQPRKKMEEMLRYVLVQ----IRA--FTSLMPTYEEVVYC--YEIHLKPELQGSGLGSLLM-GFHVIVITKVMLTCFLSNERALGFY-KRHGFETDDISPGQ-PSE Sphar VSANACVTQDLAKGEIKAIFNLTKANVSHY-----EWSDEEKMEELSRYLLVENNEDYKA--ITSFRFEMDDIMYC--YELQVAQDFRGQGLGKTLL-KALEDIMRQVVLTVQKALTPTLVMR---------WTLPGA-LRG Spipu1 VQSANEADCNLPSHLHQWAFNLVKRNLYDYIAAKDGWSDEDKLAEMAMYLIAQASDGLAG--FLYFQFVMEDVIYC--YELQLESSFQRKGLGAHLM-RILEEVMEKSMLTVFKSNEAAITFY-RKLGYDVDGISPSI-YSK Sporo1 -----------------WIWTLFEDNMKAYEAS-SGWDEKEKRKELSRFFVLRG---LLG--YSIFRFDTEEVVYC--YELQVESKAKGRGVGRTLM-DALNRIMDKTMLTVF----------------------------- Stehi1 TQKAVKATTDLSVSERELIWNIFEMNMKASEGS-SGWNPPKKRRELSRFILVQKPMEIVA--YTMFRFIREQLVYC--YELQVGKDARRTGIGRLLM-QYLGEVMDKIMLTVFRSNEPALAAY-GSMGFAVDPTSPGI-MSR Tapde11 TELANTCSQTISEPDKRACCSLVRTNLKDYEKS-SGWSEDRKYEEMARFILIRSKQALLA--FVSYQVVDEEVMYC--YEVQLDVGLRGQGIGTRLM-GLVEALLHRSMLTAFVANNAAMSFY-KRLGYVTDSTSPKI-LSK Thetr KKLARKAESEMDSDEVGWAFGLLKANMEAYVES-GGWDDDQKLSEMMKYVIATD---RLG--YAEFMYTIEKALYV--YEIQLAPDARRAGLGRRLM-QVMELAVPNVLLTVFTANVDALAFY-TALKYEVEGAAPTI-LQA Treme1 KREGGKASNNLSGRAKDALMDLCWSNITPAEGT-SRYTEADKRQELTRFLILTISQLLIG--FCSWRFDTEEVVYLKRYELHTAPQHRRQGLGRLLL-SRLEEIMDKVMLTVL-----------GLIGL------------- Trire2 IAIANDKTHELSKDDFKACFDIIELTSGVYRNS-SGWHPSMKKKEMLRYILVK----VKG--FTSLMPTFENVLYC--YEVHLVPELQG----------------------------------------------------- Umbra1 --------DDFPEHLREWALTLFKANMLTYKNS-KGWNEDEKRSELARYLVARSRTDLFG--YLLFQIVQEEVAYC--YELQIEDSARGRGLGEYLV-KLLEDIMDKVMLTVFKVNTGAFKFYTKKLAFELDEISPGI-LSK Ustma22 ---------------------------------------------------------------------------------------------------------------------------------------------- Walse1 AKNARKTSNKIPESKRNNIFTLYENNMRSFESI--EYDRNEKYEEISVIVSITKDEELVA--FVSFRFDTEEIIYL--YELQVQQSYQNGKIGAKCL-DSLHSLLDKTMLTVSKYNPRGVKFY-SRNHFELDEIDPSI-MSR Zygro1 ----------SNDKILEKQLQLIEINLGSYNKY-NRWQ-SNKWQEMLFHVSYWN---VC---FCSIMPCEESIIYL--YEIHVAPEWRNQKFGKSIL-NALKEK-SGIELTVFSSNERAINFY-RNNGFTLSYDSPSI-MCY [Cluster2538.fasta_al_trimmed; alignment length = 45] Allma1 DKSRRRVCWAARDAYLACLDRFHVACPGSWIKHFMQKREAEIRDR Ashgo11 DKASRQRCWESRDAYFECLDSFHQNCVTSWIKYFKEKRVSDSKRD Aspfu1 DRSSREKCWEGRDLFFSCLDKFEGSCAKAWVKYFKEKRVMEYNRD Aurde31 RRAQREKCWAAKDAYFGCLDDYEEACQKSWVHYFNTRRVLAEEQK Batde5 SRAERNKCWKARDLYFECLDQFEKECLPSWVQHFSMLRVKDLQSK Botbo1 SREDRKRCWESRDIYFSCLDAYGTDCAKSWVDYFNKRRVLAERQK Botci1 DRSQRSQCWEARDAYFKCLDKFEKNCATSWGQYFQKN-------- Caeel --------------------------------------------- Canalb1 NKGQRVVCWEKRDGFFECLSKFEQNCATSWVKYFQEKRYNDLVRQ Cangl NRANRKKCWESRDKFFSCLDKYETDCVSSWVKYFNEKRIVDFKRE Capow AAADRKKCYAARDAYYECAAKLEGSCLPSWVRYFDRKVLYEDYKR Catan2 DRSKRKICWDARDAYLTCLDRFQKVCPTSWVKHFINKREGDIRDR Cioin --------------------------------------------- CocheC53 SRSNRKQCYAARDAFFECLDKFEKNCAHSWVEYFKKQRVVNYQRE Coere1 SRSQRKHCHALRDKYFSCLDAFNGGCPKSWFTYFEELRAMKIKQE Conco1 KRSERKICWANRDAYFKCLDAYQSTCPSVWVQHFNDVRVSEIKNK Conpu1 SREDRQKCWEDRDAYFECLDTYEGSCARSWVEYFNKRRILAEQQK Copci TRQNRQQCWDARDAYFACLDRYHENCAKSWIEYFNQRRIIADAQK Croqu1 DRSKRAVCWSSRDTYYACLKEFHMDCAQSWVEHFNQRIVNEQRST CryneH991 SREERKACWNSRDIYFGCLDKYENNCAKAWVDYFNKRRTLELRRL Crypa2 DRTERKRCWESRDAYFACLDRFERDCAREWVTYFKKWRVADHNKK Debha1 NKSKRKECWEARDGFFDCLEKFQNKCVASWFKYFQEKRYNDLIRQ Dekbr2 NRKSREQCWESRDIFFKCLDNFQKDCVASWVKYFKQKRPFDKKKA Dicdi LNSSRTKCWEARDKYFKCLDDLNNSCLKSWSEYFIKKRISDKNKE Dmel DKAERKKCWNNRDEYWKCLEEFEQSCPGQWVKHFDRKRTYDQFKE Enthi --------------------------------------------- Falba RREARLACWAARDAFFACGTAFRKLCPAVWIDHFESRRKAAEYQK Fomme1 --------WEARDAYFACLGAYEGACAKSWIEYFNQRRVLGEQQK Fusgr1 NRQERKICWAARDAYFNCLDAFERDCAAAWVKYFKQWRVADIQKK Galma1 NRENRQKCWETRDAYFACLDRYEGNCAKSWIEYFNQRRVIAEAQK Ganpr1 DRSLRKKCWDARDEYWECLDRFERECLPSWVEHFNSKRLADMRMA Gloin1 LRSQRDLCWKLRDEYFECLDNYEKSCITSWVEYFNKRRQLEIKQR Hisca1 DRTSRQQCYIARDAFFECLDQFEGACSKTWVKYFKEKRVMEYKRD Klula1 SRSSRKQCWESRDLFFGCLDKFEQDCATSWISYFKEKRVVDFKRE Lacbi2 SREDRKKCWETRDAYFACLDSYEDSCAKSWIDYFNQRRVIADAQR Lenti61 SRADRQKCWESRDAYFACLDGYEKNCAKSWIDYFNKRRVLAEQQQ Malgl1 TRSNRQQCWDSRDAYYACLTKYEGSCAQSWIEYFNKRRVLEERQK Mellp23 DRSQRSVCWSARDAYFTCLRGYHNDCVHSWVEHFNQRVVNEQRST Mnele VLNKRKVCWAKRDAFFACLDKYYGICPGSWVKHFNKLRIQARYKS Monbr --------------------------------------------- Morel2 SRADRQNCWKVRDAYFECLNNYEKGCMKSWVDYFNKRRVLEVEQK Mucci2 TRQERKRCWFLRDQYFGCLDKYEEGCMASWVEYFNKRRVLDLRQK Mydma --------------------------------------------- Neucr2 TRSERQKCWMARDGYFACLDRFEKDCAAQWVTYFKKWRVQDIQKK Orpsp11 --------------------------------------------- Pench1 DRTSRARCWEGRDRFFACLDKFEAACSQSWVKYFKEKRVMEFNRD Phybl2 TRAERKHCWKLRDEYFTCLDKYEDGCMASWVEYFNKRRVIDVRQK Picst3 NKAKRKECWDARDKFFSCLAAFEGKCVATWVKYFQEKRFNDLTRQ Plicr1 SRQDRQKCWESRDAYFACLDSYEENCARSWIDYFNKRRVIAEQQK Polpo STS-RSQCWSARDKYFACLDAFSSSCLSSWKEYFIKKRLIEKQKS Pucgr2 NRTSRAQCWTARDGYFGCLERYHSLCMKSWVEHFNKRIVNEQRSV Punst1 SRSDRQKCWDSRDAYFKCLDAYEQNCAKSWIDYFNKRRVLAEQQK Rhior3 SREERKRCWFLRDQYFECLDKYEEGCMASWVEYFNKRRVLDLRQK Rhoto1 DRSQRSQCWESRDAYFACLDKYKGKCAGSWVDYFNKRRVLQLRQD Rozal11 --------------------------------------------- Sacce1 TRSQRKLCWESRDAFFQCLDKFEENCAHSWIKYFKEKRVIDFKRE Salro --------------------------------------------- Schco3 SRGDRQKCWDTRDAYFACLDKYEKNCARSWIDYFNQRRVIAEAQK Schpo1 RRSAREKCWEARDAYFGCLDRFETDCVKSWVNYFLKFRVQQHQQQ Sorma TRSERQKCWMARDGYFACLDRFEKDCAAQWVTYFKKWRVQDIQKR Sphar NRRARAECHSNRDAYFECLTNFEATCMPSWVKHFVRQREWNREKA Spipu1 SRSARSKCWTARDAYFACLDSFDRECLPSWVNHFGLLRVKDLQTE Sporo1 SRSERKACWDSRDLYFGCLDKYKDKCAASWVDYFNKRRVLQLRQD Stehi1 SRTDRQKCWDARDTYFACLDGYEGSCAKSWVAYFNQRRILAERQK Tapde11 --------------------------------------------- Thetr --------------------------------------------- Treme1 NKAERQACWDSRDAYFACLTDYSRNCGKSWIDYFNKRRALELRQK Trire2 NRQERTVCWAARDAYFACLDAFERDCAAAWVKYFKQWRVADVQKK Umbra1 SRRERQQCWKVRDEYFACLESYEDTCMASWVEYFNKRRVLEERQR Ustma22 TRNERKACWSHRDSYFACLTRYESNCARSWVDYFNKRRVLEERQK Walse1 TREERQACWDARDQLFSCLGDYEGACAASWIDYFIKRRMLEMRQQ Zygro1 TRSQRKQCWDSRDEFFTCLDKFEENCANSWVKYFKEKRLVDYQKR [Cluster2542.fasta_al_trimmed; alignment length = 85] Allma1 IVPFNMRDELEE-GSFDEAG-TYIWLSGLKTDIEKAALAARALRP-RETVARALARLNLLTEIAGQ-LVADVYEASYEDMMADLR Ashgo11 ------------------------------------------------------------------------------------- Aspfu1 LDAFNMRAEQEE-GKFDDQG-NYIWLEGVKKDIRRAKEAAEKLQR-GETALEALARIGTITGAADI-LMTDIYDIEREMLTRQYR Aurde31 LSQFNMKTEMDE-GKFQADG-SYVWLDDAARAIKKARRAHRAMRP-SESVLEALQRLGQITELASA-LMVDVYSATYEELLRSVR Batde5 IEPFNMDRELDE-GEFDESG-HYVWLQNLKMDIEKARRAKEAMQP-RETLIKTIQRIGRITALGSH-LFQSAYEKSYEQIVRLLR Botbo1 ISSFNMKAEMEE-GKFTEDG-SYVWMEDMERAVKKARKNKKRLQK-GETVLEALRRFGRLTDLASS-LMLDIYEEPYESLVRTVH Botci1 VDAFNMKAEQEE-GKFDANG-NFVWLEGIKKDMKKAAEAHEKLDK-AETVLEALARLGAITGAADQ-LLTDVYEQEREMLIRQYR Caeel ITAFNMKEDEEE-GHFDETG-NFIWLDGIKKKAGDQWEGDEDLKP-NQTVAKALSELKQLSGLADE-LIMDAYEWHREKFNFQLQ Canalb1 FEAFNLKEETNM-GKFDNEG-NYIWLEDYKSEINKAKQAQLLLEP-VESPMEALARLNKITNVCSI-LIDDIYELTREELTRKFQ Cangl LESFDIKEDLKE-GKFDESG-NFIWLQESKNNIPMSKLVSDRMPDQDKNIIETLAQLNILTDSVET-LESNVYQMKRQDLVNAIK Capow FTPFNLDDEMAE-GDYDEQG-NYSWADSVKEQARKSKKGNQRLEP-GETVAAALRRLGELIETAHQ-LVTNVYDDTIDTIQHQLQ Catan2 -----MRDEMRQ-GGFDESG-TFIWLAGVDADMESAAMAQEALLP-RETPSTCLGRLNLVTDLADH-LLTDIYETDREELVADLR Cioin ITPFNLKEEMEE-GDFDTQG-HYHWLDNIKKKPSQPEPTNEDLEK-GETVSKGLRRLGELTELVDQ-MTYDIYSDTFEKLQFRLN CocheC53 LDAFNMRAEQEE-GRFDEAG-NYVWLEGIKKDMKKAKEAQDKLEV-GETPMEALVRYGSITECASR-LSEDIYELPRESIMRQYK Coere1 IEAFNMRDDLEE-GSFDTQG-NFVWLNNVRSSMQLARESKERLLP-HETVFAALARVGKLTELADQ-AMSYVYEDNYEQLVRKMR Conco1 IEAFNMKGDMEL-GNFDEND-NFVWMNGIRQEMEKAKKAQEKMKP-GETILSVLSRLKKITELTEK-LILDIYSARFEDLARTLK Conpu1 LSSFNMREEMEE-GKFSSDG-TYVWMDGVEKEMKMARRRKRQLKK-GETVLEALQRLGHITHLAST-AMADIYSKTYEELVRSVR Copci ISSFNMRDEMEE-GKFTEDG-NYIWMEGLDTEIKLARKRRRELKK-GESVLEALQRLGLITQLASN-LMADPYSKTYEELVRSVR Croqu1 LSKFNMAEELTE-GRMAADG-SYVWLEGVKKAMKQAREAKKKAQN-GRSVSQTLSQLGEITDLAST-LMLDVYDMSHGTITGLLK CryneH991 ITPFNMKNELAE-GRFTAGGETYVWLSDVKEEIKKARRAHREMER-GETVLEALQRLGNLSNIVSG-LTLDVYSLSRESIQRMLP Crypa2 IDAFNMKAEQEE-GAFDEAG-NFIWLDGVKKDMKKAAEAHERLEL-GETPLEALARLGSITEAADK-LLADIYETEREVLIRDWQ Debha1 IEAFDLHEETDE-GNFDENG-NFIWM-DLKGDIERAKKAQLELEP-VETPMEALTRFSRLTDLCDK-LIVDAYELTREELMRRYK Dekbr2 IEAFNLDEEEEE-GSFDSQN-NM--TDEDKDEITKAREA-ERLEP-VQTVSELLQNLHRLTDSAYQ-LSKNAFEQP----RELLL Dicdi YDSFNLKGESEE-GYFDASG-NFIWLQEYKRELKKQNDQQTELQSDKESVLSALRRLSQLTELADS-LLVNIYSETKYSINETFK Dmel VTPFNMKEELEE-GHFDKDG-HYHWLDNIQKNAFDPAKDEENMKP-GETVKMTLQRLGQLTELANEILSMDIYQDTYESIKAKI- Enthi IEPFNLDREREE-GNFDRDG-NYTWIEMVSKSIKNEKRLQEILFP-NENSKKAICRLKQLIDACGN-LVYLIYEKTKEQLQSFVT Falba ------------------------------------------------------------------------------------- Fomme1 LSSFNMREEMEE-GKFTEDG-TFVWLEDADRAIKKARRAKRALKK-GETVLEALARLGHLTTLASN-LMVDIYNKTYEHLLRSVR Fusgr1 VEAFNLKQEMEE-GQFDQDG-NYIWLQGLKKEMKKAAAAHEKLER-AETPLEALARLGAITEAADK-LLEEIYEQERELLVREYR Galma1 LSSFNMRDEMEE-GKFTEDG-SYVWMDGLDREIKLARRRKRELKK-GETVLEALQRLGTITHLASN-LMTDIYSKTYEEIVRTIR Ganpr1 IEPFNMDDEMQN-GAFDESG-MYIWLHGTREDIEKARAAHEKLKP-GENIIRALRRLGAITAIADK-MMLDVYEETFEQIARQLR Gloin1 IEAFNMKAEMEE-GRFDEAG-NYIWLQGVRKDIEKAKRAHEKMKR-GETLLDALQRLGRLTDLSDK-MMFNVYDDTWEQILRNLK Hisca1 LDAFNMRAEQEE-GRFDEAG-NFVWLEGVRKDMRKAREAAEKLER-GETILESLARLGDVTEAADI-LLSEIYDTERELLMRQYK Klula1 ------------------------------------------------------------------------------------- Lacbi2 LSSFNMREEMEE-GKFTEDG-SYVWMEGLDREIKLARRRKRELKK-GETVLDALQRLGRITHLAST-LMTDIYSKSYEELVRGVR Lenti61 LSAFNMREEMEE-GKFSADG-MYVWMEGMEKEIKKARKLHKQLKK-GETVLEALQRVGQITHLAST-LMTDIYSKTYEELVRSVR Malgl1 IEKFNMKSEMES-GQFDEDG-NYIWLEGNRKSMKAASESQRRMKP-GESVLDALQRLGRLTHIAGV-LMMNVYDDVYEGLVRMVR Mellp23 LSKFNMAEELTE-GRMAADG-SYVWLEGVKKTMKMAREAKRKAQN-GRTVSQTLYQLGEITDLAST-LMLDVYDMSHGTITGLLK Mnele ITPFNLEDENEE-GHFDENG-NFIWLDSI--DMQKLPTAVPKLKP-SESVTKALKRLGKLTSLSDW-LLDTIYQDTYEKLNHEIK Monbr MTGFNLKDEMEE-GYFDESG-NFIWLENTRKIQMQGKHVERDLKP-HETVTQALTRYGRATSLCSV-LLYEIYDYSYEKLQIELK Morel2 IEAFNMNEELEEGGEIDENG-NFVWLEGLRKEIESARQAHERLRP-SESVVGALQRLGKLTDLCDK-MMFDIYEETYEQVVRKLR Mucci2 ------------------------------------------------------------------------------------- Mydma VTPFNLKDELEE-GHFDAQG-NYIWLDSVNRNVL-----NEDMNP-GETVLKSLRRLGKLTGLADD-VLFQIYEKSYEQLAFETK Neucr2 IDAFNMQAENEE-GAFDEAG-NYIWLEGLKKEIKKAALAHEKLEK-GETALEALARLGAITEAADK-LLPDIYDKEREWLVREYR Orpsp11 MMPFNMDKDLEE-GDFDENG-HYIWLEDIKSDIMKAKAAKEKMKP-KETLLNAMKRFGAITAIAEK-MMY--------------- Pench1 LDAFNMQTEQEE-GRFDDQG-NYVWLEGVKKDIKKAKEAAEQLER-GETILEALARLGSLTGAADI-LMIDIYDTEREMLTRQYR Phybl2 ------------------------------------------------------------------------------------- Picst3 IEAFNLREEALE-GQFDLDG-NYIWLNDYRSDVLNARKAQEQLEA-AETPMEALARLARITELCDK-LITDTYDMSREEFMRLYK Plicr1 LSSFNMREEMEE-GKFAADG-TYVWMDGVEREIKKARRRKRHLKK-GETVLEALQRLGHITHLASS-IMADVYSKTYEELVRSVR Polpo VVPFNLAEEKSE-GRFKADG-TYEWLKEYRKEMAKLEAAERELQP-GETVLTALRRLGDLTEASNY-LLMNIYSDKRESVQAVLN Pucgr2 LSKFNMAEELQE-GRMAADG-SYVWLEGVKKTIKQARDAKRLVGD-GRTVSQILCHLGEITDLASM-LMLDIYEMSHGSITGILK Punst1 LSSFNMREEMEE-GKFTEDG-MYVWLDGMEREVKQARRRKKALKK-GETVLEALQRLGHITHLAST-LMTDIYSRTYEELVRSIR Rhior3 ITAFNMKAELEE-GSLDEKG-NYIWMEGIRKDINHAKAAQEKLQP-GQSVQEALTSLAIITELADQ-MMFNVYEDTFEIMVRHLR Rhoto1 LTSFNMKEELGE-GRFTSDG-TYVWLDGLKRSIRAAKEAKERVRP-GETVARALTRLGRLTHFAST-LLLEIYDETYEQIIKTLK Rozal11 IDAFNLDEEMEQ-GYFDDAG-MYVWLQGIREDIQKAKLAKEKVEP-GQSIPKAMKEF-LMTDICSQ-FIYSIYEETYESLEEKVN Sacce1 ------------------------------------------------------------------------------------- Salro ITGFNLEEEMEE-GHFDEQG-AFHWLEGVVK---EGEDDDGDMRE-HETVNAAIRRLDRLIELADQ-LMFTIYEDTYEKLVHEIK Schco3 LSSFNMREEMEE-GKFTEDG-SYVWMEGVERQIKLARRRKRELKK-GESVLEALQRLGTITHLASN-IMVDVYSRTYEELVRSVR Schpo1 RMSFNLKEDMEE-GDFDENG-NFIWLNGSKKSIAAAREAEQKMER-DESILEFLQRQSLITAGLTF-LEEDIYSETRESLQRIYQ Sorma IDAFNMRAEQEE-GAFDEAG-NFIWLEGLKKEIKKAAAAHEKLEK-GETALEALARLGAITEAADK-LLPDIYDKEREWLVREYR Sphar ------------------------------------------------------------------------------------- Spipu1 ITPFNMEEEMEE-GGFDEAG-HYIWLQGVKEEIEKAKAAHDRIQP-GESIPRALRRLAHLTTYANQ-LLLDAYDLTYEQVVRKLR Sporo1 LSSFNMKEELEE-GRFSADG-SYVWLSGLKVQIRQAREAKERVRP-GETVAGALNRLGRLTHFAST-LLLEIYDQRHEDIVKTLK Stehi1 LSSFNMREEMEE-GKFSADG-MYVWMDGLEREIKLAKKRKKELKK-GEFVLEALQRLGELTHYASA-LMIDIYSKTYEELVRSVR Tapde11 LDGFNMRAEMEE-GKFDAEG-NYIWLKDVRKDIAAAREAVERLDR-GETLLEALSRLGRMTELANR-LMIDVYDTEKEGLARAYK Thetr ------------------------------------------------------------------------------------- Treme1 ITPFNMKQEMQE-GKFTADGDEYVWLADVEEDIEKVRKAHEEMER-GETVLEALQRLGNLSNVISG-LTLDVYSLSKESIQRMLP Trire2 VEAFNLKEEMEE-GRFDQDG-NYVWLEGLKKDMKKAAAAHEKLEK-TETPLEALARLGAITDAADK-LLEDIYDQERELLVREYR Umbra1 IMAFNMKEDLEE-GEFDEEG-NYIWLQGLKKDIAKAKAAQEKLQP-GENVRDALVRLGRITALADQ-MMFGIYDETYEAILRHLR Ustma22 VTGFNMKEEMRT-GKFDADG-NYHWLTGVKSKILEARRAQQKMHR-YETVQRTLQRLGTVTHLSSV-LMLDIYDQTYEQLLHDVR Walse1 LSAFNMKEEMRE-GQFVDDG-TYVWMDNTKASRKRIREAHKETQR-GETVLEALQRLGKFTELVNI-MVAEVYDWEHEQFVRNVK Zygro1 ------------------------------------------------------------------------------------- [Cluster2545.fasta_al_trimmed; alignment length = 201] Allma1 MRQALTNPVFGARGDFVTSPEISQMFGELVGVWLVELGPGRGTLMADM-LRAVVFVEASLRNEQMATITMLVAHEFFDALPVYKFKHVWREIMVDVLAPQKTNAVVEVSPESTGYMQRIGDLLGGAALVVDYGN-DAIRDHQFTDPGQADLSVDVDFSLLKWALTTQRHFLASLGIYDRMQALAFNRLVSEMGTVYKCLAV Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MRQVLTSPVFGKKGDFVTSPEISQVFGELVGIWLIEVGPGKGTLMDDM-LRTIYLVEASLREVQKQRLPFIFAHEFFDALPIHAFESIWREIMVTTLAKASTPSSIEVSPESRIYASDFARRISGAALIMDYGTMSGIQHHRTVPPGQVDVSADVDFMALAEAAVEQGDFLQVMGIAERMQQLGWKRLIEGMGKIYKFMAI Aurde31 MELCLQHPIIGAKGDFVTSPEISQHFGEIIGIWLVELGPGKGTLIGDV-MRTVDLVESSLEQQQREALTAVIAHELFDALPIHIIEKTWQEVLVDVLS-GPSLLAIEVSPLGYDLARKVGQFIHGAALLVDYGD-EAFYKHKIVDPGETDLTANVDFAFLKEAAISQAEFLKRMGLDALLARSAAGRLVDGMGRQYQFLGL Batde5 MRQALIHPVFGPHGDFITSPEINQMFGELMAIWIIELGPGRGTLMADM-LTTVHLVEASLRKTQAQMLSFIIAHEFFDAMPVYKFQKTWREIMVDICAPSATKASIELAPDVVGVSKAIAERVGGIALFVDYGR-DGIRNHKIVHPGDCDLSADVDFSAIQHAVVPQGLFLEKMGIGARAMALAYERLVDAMGQAYKIMAI Botbo1 MQMCLSHPVFGARGDFVTSPEITQIFGELLGIWLVELGPGRGTLMDDI-LRAVHLVETSLRDVQKDKLSMVVAHEFFDALPIHILKKTFRELFVDAVSPVPNVTSLEVSPASWTIARAIGELVGGAGLIVDYGD-AGFRKHQIVDPGCSDLTANVDFAYLKEALIPQRDFLINLGMGTRLEALAAKRLVDGMGTQYKVMGI Botci1 MRMCLTSD-------------------------------------------TVYMVEASLRDTQKQLLPFIVAHEFFDALPIHAFQSVWREMVVSTLSKASTPHSIEISPESHAIVADFASRISGAALILDYGPSDGIKAHQRVSPGVVDLSADVDFIALAEAAMEQGGWLESMGIKERAEMLAWKRLVDGMGKVYKVMAV Caeel MKTCVSAPVFGAKGDFITSPELTQLFGEMIGVWLVELGPGRAQLMNDV-LNAVHLVETSLIDEQEKSLTVFIGNEFLDALPIHQFHKSWNEVYVNLHTKGLIPSAWECSPESGTVVNQIVDRIGGFSLLVDYGH-DAYKNHKQVDPGLADLTADVDFGYLSTLVNEQREFLAQLGIEHRLRRLSYNMLMGDMGLKFKAWAL Canalb1 MRQCLTHPLNLRTGDFITSPEISSVFGEMIGIWFIEFGPGKGTLIHDI-MKTIALIEASLRKEQWKLLNFIVAHEFFDALPIKSFIREWRELVVETIAPKETPSSIEICPDAELYIMKMAKLLKGAILVIDYGTENGIYQHKFVSPGEVDLSIDVDFQALKQLTLKQGDWLHNIGIGYRIDQVAYRRLTD-MGSIYKFMAL Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow MRTVLTAPVFGAGGDFTTSPEISPLFGEMIGAWLIEFGPGRGTLMHDV-LRIVHFVEKSLLRVQ----SLILAHEFFDALPALSFTRTWREVLVDVTANAHTVASLTLSPDSFILTENLSKRIGGAALIIDYGYATAFRGHKEVHIGMSDLTVDVDFEYLAAAA--QGEFLEALGIGQRLARLGVERLTSDMGQRFKAMAI Catan2 MRRCLTHPVFGAKGDFITSPEISQMFGELIGVWIVELGPGRGTLVADM-IRSVVLVEASLREVQLESITFLVAHEFFDALPVFKFKKTWREIMVDVIAPEKTQSVIEVCPEATGYMHKIADLLNGSGLIMDYGN-DAIRNHQFTHPGLSDLSADVDFSLLKWSLTTQRHFLARMGIEDRARQLAMTRLMAQMGVVYKMMAV Cioin MKETLTNPMLGNDGDFVTSPELNQIFGEIIAIWIVELGPGRGTLAEDI-LRTYSFVEVSLSKIQHERLTIFVAHEFFDALPVHKFVNSWQEVYVDVVLPKPTIASIEVSPQSGIIVQEMAQRIKGAALIVDYGH-YAFKSHQLCEVGEADLTADVDFKYLKQSIIPQHVFLRNMGIDTRLMMLSYEMIMNQMGERFQFFSL CocheC53 MRQCLTHPQFGTKGDFVTSPEISQIFGELIGIWIMEVGPGRGTLMDDV-LRTIYLIEASLQKQQAKLLPFILAHEFFDALPIHVFQNVWHELVVSTVSKTPTPHSIEISPESLAYVSDFAVRISGAALILDYGPLDGIRSHTTVSPGLVDLSADVDFVGLADSAVEQSFFLSTMGIKERADRLGWKRLVDGMGKTYKAMAI Coere1 MQLALTSPVLGRKGDFVTSPEISQMFGEIIAVWFVELGPGHGTLMDDI-LRAVHLVERSLRRMQHKKLPLVIAHEFFDALPIYKFERGWHEILVDDIAASAAANQVEVSPESARIMAQISKWIRGMGLVIDYGQ-DGIKEHKFARPGSMDLTADVDFRYLRAAAIEQGTFLHLMGIQARLQQLCYKRLTDSMGRIYKVLSV Conco1 ISLCNTHPAIGPKGSFVTSPEISQLFGEMVALWFIEFGPGNGTLLNDV-LRTVNLVEMSLSTKQAKSWTFLIAHEFLDALPIRRFKKTFRETLIDIQSKTPTEGNLELSSDLIQFLPKFFNLIGGLGLIVDYGD-NGIKDHKFVNPGEVDLSADVNFKLISQLAQYQKDFLHKMGIQYRLAQIGYKRLCDDMGKLFKFMAI Conpu1 MQLCLSHPVFGASGDFVTSPEISQVFAELIGVWIVELGPGRGTMLEDICLHVIHLVDSSMQKLQEERLTLFIAHEFFDALPVQVIERTWHEIMIAVLSPQPTASSIEVSAASAKAAHTIGELLGGAGLVVDYGK-EAFKEHRQVDPGECDITADVDFALLKESFLSQGNYLRRMGIDLRTRVLASKRLIDGMGEQYRIMGV Copci MQLCLSHPVFGTSGDFITSPEISQVFGELVGVWLVELGPGRGTLMDDI-LRIVHLVETSLRSVQKAKLTMLVAHEFFDALPVHVVQKTWNEVMIAVLNPLPSPASIEVSPTSFRIAHQIGRLLGGCGLVIDYGA-DAFKEHKIVDPGECDITANVDFAYLKEAMITQADFLERMALQTRVEALAANRLVDGMGTQYKVLGI Croqu1 MDLCLNHPPFGTSGDFITSPEVSQIFGELLGVWVVELGPGRGTLMADM-LRTIHLVENSMRKLQRAQLTAIVAHEFFDALPVHIFQKTFREVLVDVLSPAPTLASIELSPMSPHIATQLTQLLGGAGLIVDYGD-SGFHQHQIVDPGLTDITTNVDFASLQKAIITQREFLLRMGIEVRASRLACDRLISGMGNQYKVLGI CryneH991 MQFCLSHPVFGQKGDFITSPEISQIFGELVAIWIIELGPGRGTLMDDV-LRTVHLVENSMREVQSRTLTLFVAHEFFDAMPINVFEKTWREVLIDTLSPSPTTLSIEVSQDSYKIMHRLGQV-GGCGLVVDYGA-DAFRKHEIVDPGNCDLTANVDFAYLRESLISQAQFLISLGLQPRLRKLGAKRLIDGMGSQYQVMGV Crypa2 MRMCLTGDQFGLKGDFVTSPEISQVFGELIGIWLIEVGPGRGTLMDDM-LRTIYMVEASLRIAQKTLLPFIVAHEFFDALPIHAFQVVWREMVVSTLSPTATRHSIEICPDLSLYATDFAARISGAALILDYGPGDGISRHRRVSPGLTDLSADVDFAAIAEAAVDQGLFLESMGIRERAEVLAWKRLVDGMGKVYKALAI Debha1 MRQCLTHPLNASSGDFITSPEISSMFGEMIGIWIIEFGPGRGTLMYDC-LKSITMIEASLRKEQWKLLNYIVAHEFFDALPIKSFQKTWRELVVETLSPKETSSSIEICPDAELYVLKMAQLLMGSVLIIDYGISEGIYKHKFVSPGEVDLSVDVDFTNLKNVTVEQGDWLHELGIGYRTDQLAYQRLTGSMGKIYKFLCL Dekbr2 MKECLINPLDTKTGDFITSPEISSTFGEMCALWFIEYGPGRGTLMYDM-LRIVVFVEKSLINEQYNAINFVIAHEFFDALPINRFVKTWREYLVDVESTHETPSSVEICPDAHSYMYEMADIVIGAGLVIDYGKATGIRNQKFVDPGEVDLSADVDFSDLSHLL-DQGDWLNNMGLGYRIDQLSYKRLTSEMGKVYKVLGF Dicdi IKEVLTNPVFGKGGDFITAPEVSQLFGEMIGIWIVEMGPGRGTLMKDI-LRSVHLVEASNKKTQKQNLTLFLAQEFFDALPIHVFRFSWCEVLVDVQSKGPTLMTVELGLAGLAISQQIANRIGGAALIIDYGY-DAIRDHEFVDPGTADLSVWVDFQTIRKTVVDQGIFLKEMGIEHRLAQIGYKKLVDEMGTNYKVITI Dmel MREVLTNPVFGREGDFITSPEISQIFGELVGIWLVELGPGRGTLARDV-LKVMHMVEVSLSKAQAQRFSLVLAHEFFDALPVHKLQLVWQEVLIDVLSRSQTP--LEHSLETERQVGLLAERIGGIALIMDYGH-FAFKQHKLHDPGSADLTADVDFKLVRHIAVEQGLFLQRMQGEARLEQLGYEMLTDQMGTRFKFLAM Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MKECLTNPALGRAGDFVTSPEVSSLFGDCVGTWLVELDPGKGTLMKDV-LRVVQLVEASLRAVQAAALFVLLAHEFLDALPVFQFVRPWSEVLVSTLSDGPTPNSIEISAAVADVSARIAQMVRGVALIVDYGV-DGIRQHQFVHPGTVDLSADVDFSLVRRAAMTQHEFLRDMGIGVRLQQVGVRRLVDQMGQIYKFIAI Fomme1 MQFCLSHPVFGKAGDFITSPEISQVFGELIAIWIIELGPGRGTLAADA-LRTLHLVETSMRRLQGETLTVVVAHEFFDALPVHILERTWHEIQITVRNPESTTLSLEVSPTNFKLARTLAELVGGSALIIDYGR-DAFKKHKIVDPGECDLTANVDFALLKEAILTQRDFLINMGIDARVLRLAAKRLIDGMGVQYKVLGV Fusgr1 MRMCLTGDQFGTKGDFVTSPEISQIFGELIGIWIIEVGPGRGTLMDDM-LRTVYMVEASLRSAQKELLPFIIAHEFFDALPIHSFQSAWREMMVSTLSSTPTRHSIEICPDASIFATDFATRVSGAALILDYGTSDGIRHHRRVSPGLVDLSADVDFTAIAEVAVTQGDFLGVMGIRERAEQLAWKRLVDGMGKLYKVLAI Galma1 MQLCLSHPVFGTDGDFITSPEISQTFGELIALWLVELGPGKGTLMGDI-LRVIHLVETSMRDLQSTRLTMLVAHEFFDALPTHILQRSWHEVLIAVLSAKPSNVGLEVSPMAFKIARKVGELLGGCGLIIDYGG-DAFKNHEIVDPGHCDITANVDFAFLKEAMIPQGDFLTRMGLALRLRTLAAMRLVDGMGRQYQVLGI Ganpr1 MRFSLTNPVFGKKGDFVTSPEISQMFGECVGVWILELGPGRGTLMNDV-LRTVHLVEAGMRSMQARKLTITIAHEFFDALPIHRFELTWREIMIDVLSPNPTPASIEFCPEGAALIDQIARRVGGSALIMDYGH-DAIKDHKFVDPGTTDLSADVDYSMMKDVIVTQSRFLHSLGIRERLMALQYERLTAQMGDIYKVMAV Gloin1 MKHVSTNPVFGAKGDFITSPEISQMFGELIGIWLIELGPGRGTLMEDM-LRVIHLIEISLSKLQFKRLSLIVAHEFFDALPIHRFKLTWREYMVDILSPDSTKESIEISSDSWNITQKISNQIGGAALIIDYGQ-DAIRDHKFVHPGHSDLSADINFSYLKESTVTQSKFLHSMGITTRLSMLSYKRLVDTMGRIYKVLAI Hisca1 MRQCLTSPLFGAKGDFVTSPEISQIFGELLGVWIIEFGPGKGTLMGDM-LRSVYLVETSLREVQRKLLPFFLAHEFFDALPIHAFQSIWRELVVSSLAKASTPSSIEISPESQACVQDIARRISGAALILDYGTTSGIRKHRLVSPGEVDISADVDFTALAEAAMEQGPFLEALGISERAAQLGWKRLVEGMGKLYKALAI Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MQLCLSHPVFGTRGDFITSPEISQVFGELVGVWLVELGPGRGTLMDDV-LRVVHLVETSMRSLQEAKLTMFFAHEFFDALPIHTLQKTWHEVLIDVLSRSPSATSIEVSPTSFRTARQVGELLGGCGLIIDYGD-DAFSNHKLVDPGDCDLTSNVDFTYLREAVIPQYMFLEKMGLQLRLDSLAAERLVSGMGTEYKVMGL Lenti61 MQMCLSHPVIGSRGDFITSPEISQVFGELLGVWLVELGPGRGTLMHDM-LRVIHLVETSMRSAQKSKLTLVVAHEFFDALPFHLLQKTWQELLVTVLSPTPTASAVEVSPASFKIARQVAELLAGSALIVDYGG-DAFKDHKIVDPGECDLTVNVDFTYLQEATIPQALFLHRMGLQARVNALAAGRLVDGMGSQYKVMAL Malgl1 MQACLTNPILGTRGDFITSPEISQVFGELLAVFIVELGPGRGTLLCDM-LRTIELIESSFIEQQEANLTIVVAHEFFDALPIHIFEKHWREVMVDVLSPGPTAWTVEISPASWTVARKIGEWVGGCGLVIDYGG-MAFRAHKLVDPGQSDLTANVDFTFLMHAILSQQDFLTALGLSLRVKNLAANRLIEGMGTQYQVMGI Mellp23 MNLCLNHTPFGKLGDFITSPEISQIFGELIGVWIIELGPGRGTLISDI-LRTIHLVENSLRKIQEEKLSMIIAHEFFDALPIHVFQKTFREILVDVLASKPTIGSIEISPLSLSVAFHLSKLL-GSGLIVDYGD-DGFYKHRVVDPGLTDLTANVNFSKLKEIMISQREFLLKMGIEVRKQKLSVDRLISGMGTQYKFLGI Mnele MQDVIMDP-IGHKGDFITAPELTPVFGEIIGAWFTELGPGRGTLMRDI-IDTASLIEISFIAEQEKLLTLYVMNEFLDALPVNQFQKTWVEIMVD-YTTYKTGRSIEHSPMSGKVVTALSERIGGAALIIDYGE-DAFKNHQQVNLGLCDLTADVNFRDLKKSIITQSSFLTLMGIGERFRQLAHNFLCSEMGDRFKV--- Monbr MQEVLTSPQFGGQGDFITAPGVSHMFGEVL----------------------INLIESSLSAEQEATIVIVVANEFLDAAPIYQLQYQWHERLVD----------------------------------------D---------PGEL---------------------------------------------------- Morel2 MRQVLVNPVFGTQGDFITSPEISQMFGELLGIWIVELGPGRGTLMMDM-LRAVHLVEASLRKMQRQTLSLIVAHEFFDALPIYKFEKTWRELVVDVLAPGPTQASIEISPDSFRVAHDMAKHMGGSALIVDYGK-DGIHKHKFTHPGKVDLSADVDFNYLKQATVTQAHLLHSLGIGARLDMLSYHRLVDEMGNVYRVMAM Mucci2 MRQVLVNPVFGKQGDFVTSPEISQVFGELCGVWIIEFGPGRGTLMSDM-LRTVHFIEASLRKMQRAALSFIMAHEFFDALPIHSFEKTWRELMVDVKSPNQAAMSVDVSPDCWSVMDKISRYLGGTGLAIDYGQ-DAIKDHKIIHPGSADLSADVDFSFLKQAIITQKDFLQSLGIQARIETLGAERLMDAMGRIYKVLAF Mydma MKEALTNPVFGAKGDFTTSPEISQMFGELIGIWLVELGPGRGTLMADI-LRVVNFVEVSMISLQKQNLTFYLAHEFFDALPVHLFKKVYHELLVGVTAPGPSPVACEVCPEAAVVMSYISENIGGCAMIIDYGE-SGYKNHVLVDPGSCDITANVDFGFLKRCIITQRSFLLQMGIKQRLKVLSLDYLISKMGEKFKCFAL Neucr2 MRMCLTGDQFGAKGDFVTSPEISQVFGELCGLWLIEVGPGRGTLMDDM-LRTVYMVEASLRMAQKNLLPFIMAHEFFDALPIHAFQLVWRELLVSTVSPSPTRHSIEICPDAFLFASDFATRIRGAALILDYGPGDGIRKHHLVSPGLTDLSADVDFTAIAEAAVEQAWWLEGMGGRERVEQLSWDRLVDGMGRIYKALAI Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MRQVLTSPVFGKHGDFVTSPEISQVFGELIGIWLMEVGPGKGTLMDDM-LRTIYLVEASLREVQKRLLPFIFAHEFFDALPIHAFESVWRELMVTTKAKASTPSSIEISPESRIYAADFARRISGAALIMDYGTLSGIKSHEKVAPGRVDVSADVDFTSLAEAAVEQGDFLGAMGIEERMRQLAWKRLVESMGQIYKVMAI Phybl2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 MRQCLTHPLDHRSGDFITSPEISSVFGEMIGIWIIEFGPGKGTLMHDV-LNTINLIEASLRQEQWKLLNYVLAHEFFDALPIKGFERTWRELLVETLSKKETPSSIEICSEAELYIMKMAQLVLGAVLVIDYGLVNGIYQHKFVSPGDVDLSVDVDFDNLVNLTIDQGDWLHNIGVGYRVDQLSYRRLTDSMGKIYKFLCL Plicr1 MSLCLAHPVFGSRGDFTTSPEISQVFGELIAIWLIELGPGRGTLMADM-LRTVHLVETSMRAVQK---TMLVANEFFDALPVHVIEKSWREVLISVLSSSPSPISIEVSPVAYKIARKIGELLGGCALVVDYGG-DAFKDHKIVDPGECDLTVNVDFAYLKEAVILQASFLDRMGMRHRVDALAAQRLTDGMGKQYQVMGI Polpo IKECLTNPVFGSGGDFITAPEISQLFGEMIGIWIVELGPGRGTLMHDI-LRSCHMVEVSLRGMQKTKLTLYIAQEFFDALPINVFKFSWCEVLVDVMSSGPTLMTVELGVAGLGIAQKIALRISGAALIIDYGQ-DAIRNHEFVDPGSADLSSWVDFSSIRKCVVDQGIFLKEMGIEHRIERISYHKLVSEMGSTYKVITI Pucgr2 MKLCLHHPPFGKQGDFITSPEISQVFGELIAIWIIELGPGRGTLMADI-IRTIHFIENSMRALQDQKLTMVIAHEFFDALPVHIFQKTFREVMIDALSPGPTLASLEVSPSANQIAGQISQLLGGTGLIIDYGA-EGFYQHQIVDPGLTDITANVDFASLKRSMITQRQFLLSMGIEVRTKRLSSQRLISGMGDQYKFLGF Punst1 MQLCLSHPVFGKAGDFVTSPEISQVFGELTGIWLVELGPGRGTLMSDI-LRIVHLVETSMRAMQKTVLTMVIAHEFFDSLPFHLLQKTWHEVHIDVLAPTPSPTALEVSPAAFKIAHKLGQLL-GCALVIDYGG-DAFKNHKIVDPGECDLTVNVDFAYLKEALLPQHAFLKRMGINMRVEQLAARRLIDGMGTQYQVLGI Rhior3 MRQVLVNPVFGKSGDFITSPEISQVFGELCGIWIIEFGPGRGTLMSDM-LRSVHLIEASLRKLQREALSFIMAHEFFDALPIHIFEKAWREMLVD-----------------WQLIDKIAKYLGGSGLAIDYGQ-DAIKNHQIIHPGTADLSADVDFSFLKQTIITQSNFLQALGIHTRVEKLGAERLMDEMGRIYKVLAF Rhoto1 MTLCLNHPVFGKEGDFVTSPEISQVFGELLGIWIIELGPGRGTLLADV-LRTIHLVEASLQRVQKQKLTVLIAHEFFDALPIHIFENTWREVLIDVLAPNATPASLEVSPSSWEIARDLARVVGGAGLVVDYGD-AGFRKHQVVDPGHTDLTANVDFAYLSEAMLSQRTFLSALGLEPRLASLAAKRLVDGMGEQYKFLAV Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro MKHVLTHPLDNDRGDFVTSPQLSQMFGEMVGAWFVELGPGTGLLMHDI-IQSVHLVEASMSQQQYETLTFLYAHEFFDTMPTHQFQLTWRERMVDVLSPKETVQSGEVSFEAMEQAELVAHTLGGRALIFDYGD-TAFRDHQQVHPGSADLTTDVNFDHLLVAAVTQRQFLLRCGLQQRADALHTRMLTDEMGERFKVMAM Schco3 MSLCLGHPVFGKAGDFITSPEISQVFGELIGIWLVELGPGRGTLMEDI-LRVVHLVETSMRKLQKSKLTMVLAHEFFDALPIDIYQKMFLEKLVTYSAPKKTGFAAEICWPAWDIAASISKLLGGAGLVIDYGG-EAFKQHKIVSPGQCDLTANVDFKFLRHAFLTQAAFLQGMGVDVRLQKLGVERLIGGMGKEYKVLGI Schpo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma MRMCLTGDQFGAAGDFVTSPEISQVFGELCGLWLIEVGPGRGTLMDDM-LRTVYMVEASLRIAQKNLLPFIMAHEFFDALPIHAFQLVWRELLVSTLSPSPTRHSIEISPDTYLFATDFATRIRGAALILDYGPGDGIRKHHLVSPGLTDLSADVDFSAIAEAAVEQGWLLEGMGGRERVESLSWERLVDGMGRVYKALAI Sphar --------------------------------------------MADI-LKIVHFVEMSLAKTQAQTLPMIVAHEFLDALPVHQFVYTWRERMIGVLAPSATASSYEVSPDSLHTAHQIAQAVDGMALIVDYGNKEGYKAHVMIEPGEIDLTADVSFQAVAKVCMSQGDWLRQMGIHTRTKQMSTKRLIDGMGSLFQFLSL Spipu1 MRSALTHPVFGAAGDFTTSPEISQMFGELVAVWLVELGPGRGTLMSDM-LRAVHLVEASLRRVQAEKLSMIIAHEFFDAMPIYKFELTWKEIQVATLSPGPTNASVEVSPDSYAVANHVAQRIGGSALFIDYGR-DGIRKHNFTNPGDSDLSADVDFSFLRDAAITQSTFLRAMGIGPRMNMLAFDRLVSGMGTVYKFMAL Sporo1 MTLCLNHPVFGKEGDFVTSPEISQVFGELLGIWVVELGPGRGTLLADV-LRTIHLVEQSLQTVQKEALTVAIAHEFFDALPIHIFEHTWREVLVDVLSPTQTPASLEISPSSYEIARGFAKLLGGAGLVVDYGD-AGFRKHAVVDPGHTDLTANVDFSYLAEAMLTQSKFLTSLGLAPRLASLAAKRLIDGMGGQYKVLGV Stehi1 INLCLSHPVFGAQGDFITSPEISQVFGELVGVWLVELGPGRGTLMDDI-LRTVHLVETSLRVIQEQKLTMLVAHEFFDALPVHLLEKTWKEVLLTVLSPEPSPVSIEVCAAGFQVARKLAGL-RGCGLIVDYGD-EAFKDHKIVDPGQCDLTANVDFAYLKEAMITQSTFLTRMGLDIRLNALAAKRLVDGMGKEYRVLGI Tapde11 MRQCLTNPPFGKPGDFVTSPEISQMFGELVGIWIIELGPGKATLLDDL-LRAIHLLEASLRDVQRQKLPFLLAHEFFDAMPTHAFECTWRELMVDTLANKSTPLAIEVSPEAQGIANKIASLLGGSGLVIDYGPIDGIKNHKIVSPGTVDLSVDVDFAGIAEQVVLQGDWLHKLGIGARATVLEYKRLVDGMGKAYKVMAI Thetr MRTCLTHPVFGAAGDFVTAPEVSQLFADSLAVYYVELGPGRGTLASDL-LRAVHLVEASTLRLRLRKVIYVVANEFFDALPVHQLLRVWRERLVGTLSDAPTLACIEISPDSWAAAKELARVLPAPAFIIDYGWASAIKDHAVLTPGDADLTADVDFGTLAKVLLDQGVALQKLGIAARTETLGVERLVAAMGSIYKALFF Treme1 IQFCLSHPIFGRKGDFVTSPEISQVFGELVGIWLLELGPGRGTLMDDI-LRTVHLVENSMQQLQADKLTFVVAHEFFDAIPINLFEKTFREVLVDTLSREPTPLSLEIAGESWRIMRRLGEIIGGAGLIIDYGG-EAFQKHKLVDPGEADLTANVDFEYLKESLISQSDFLLKLGLQPRLEKLSAQRLIDGMGSQYRILGL Trire2 MRMCLTGDQFGTKGDFVTSPEISQIFGELLGIWLIEVGPGRGTLMDDM-LRTVFMVEASLRETQKKLLPFIVAHEFFDALPIHIFQSAWREMMVSVLSSSTTRHSIEICPDASLYAADFAARISGAALILDYGTADGIRHHRLVSPGLVDLSADVDFHAIAEAAVTQADFLMLMGIRERAEALAWKRLVDGM--------- Umbra1 MRQVLVNPVFGTEGDFVTSPEISQMFGELAGIWLVEFGPGRGTLMDDM-LRAVQLVEASLRKVQRAKLSMIMAHEFFDALAIHTFEKTWREMLVDVRCPQETNASIEISPDSWEVMRKMAELVGGVGLAIDYGQ-DAIRQHKIVHPGSADLSADVDFLALKNAAVTQGQFLHSLGIETRLKVLSYERLVNEMGQIYKVLAF Ustma22 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 MSVCTYHPPISKQGDFITSPEISQVFGELIAVWFVELGPGNGTLMSDI-LRTVHLVETSLRETQKSTLTFIVAHEFFDALPIHVFQKTFREVLVDVVSKQQTPMSLELNVEGYYIANAIGSLLGGAALIVDYGQ-DGFRNHKQVDPGECDITSDVDFGVLRESLMTQRDFLIKMGVAPRLDTLSAKRLLDGMGNQYKFMAG Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2549.fasta_al_trimmed; alignment length = 67] Allma1 RILRTH-RA-FPPELRYMGDQYARDEFRRHQHVNAVFISQFYEQWRFYADEMGRPLDLDQMNQLWEL Ashgo11 RILRAH-RT-FPPAQRALGDEYVKSEFKLHKNINPVHIIGFLASWQDYFHMIEGTLSVDQMSQLYEL Aspfu1 RILRVH-RRKLDPEMRILGDSYVKSEFRAHRNVNPLHIIGFLTEWQLYAQKLGEKLDLDKMSQLYEL Aurde31 AILRAH-RR-LPLEMRSLGDTYFKAEFRRHREVNPVHIMGFLAQWKLYLDDLGKPLDLEKMTQLYEL Batde5 ------------------------------------------------------------------- Botbo1 ALLRVH-RR-LPLEMRSLGDEYVKAEFRRHRDANPVHIMGFLSQWKYYLEDLGKKMDFEKMSQMYEL Botci1 RLFRAH-RKHLPREMRLLGDEYIKSEFRQHREVNPVHIIGFLTEWQMYAQKLGERMDIDKMSQLYEL Caeel SILRLH-YG-LPAQARLMGDTYVKDEFKRHKTAKPEFVKPFITEWTNYCVMLGKDLDMEQLSQLVEL Canalb1 AILRAHHRK-LPQELRYLGDQYVKKEFKDHKKINPLHIVGFLTEWQDYLKQIHGKLSLDKMSQLHEL Cangl RILRAH-KL-LPPMQKEMGDKYVKSEFELHRTINPLHIVGFLASWQDYLHQIEGSLSLEKMSQLYEL Capow --------------MRVMGDMYVRDEFKRHKGASQAQV--FMAEWKVSSEHWARALR-----HLYSD Catan2 ------------------------------------------------------------------- Cioin RILRLH-EG-FPLDLKVIGDQYVKSEFKLHKDSPPEFVPEFLQQWNEYADSLGKNLDLDNLSQLFEL CocheC53 RLLRSH-RKRLGPEERLLGDMYVKAEFRAHRDVNPVQIIGFLSEWQTYCQMLDAKMDIDKMSQLYEL Coere1 SILRIH-RR-LPREIRFVGDQYVRGEFRNHRTVDKKYLEPFFKQWTAYL------------------ Conco1 SIFRIH-RT-LPQDLRFLGDKYVLEEFKRHKDLDP-YLGGFNKQWNFYLIELGQSLGLKKLSTLYEL Conpu1 SLLRAH-KR-LPYEMRSLGDDYVKAEFRRHKDVNPVYVMGFLSQWKMYLDQL-KRMDFEKMSQLYEL Copci RILRVH-RN-LPPEMRSLGDVYVKSEFRRHQKVNSGHLLGFLSQWKRYLDEMGKRLDFEKLTQLYEF Croqu1 RLLRIH-RTALPSEMRSLGDVYVKDEFRRCRSINPIQIIGFLGQWKIYLDTLGRQLSLEKLSQLFEL CryneH991 RLLRAH-RL-LPVDMRYMGDSYVKSEFRLTRTTNPLHIIGFLSQWKIYLDEIGKKLDFEKLSQLYEL Crypa2 --------------MRLLGDEYVKAEFRAHREVNPAHLIGFLTEWQLYAQKIGDKLDIEKMNQLYEL Debha1 ALLRAHANK-LPVELRPLGDQYVKAEFKAHKNINPLHIVGFLAQWQDYLKGINGKLSLEKMSQLHEL Dekbr2 EILRAH-RK-LPKAQKELGDEYVRAEFRAHKNINPLQIVGFLSSWQNYLVVVKYRIPLEKMSQFYEL Dicdi NILRCH-KI-LQEPMRSMGDQYVKTEWKLHKKATPKQAIQFYEQWNIYCNILGQDLNMKSLNQLDKL Dmel TILRLH-RG-LPAELRALGDNYVRDEFRRHLKCNPMEAQLFMTEWARYASTIGEEIDVEMLKQLYEL Enthi ------------------------------------------------------------------- Falba QILRAH-RA-LPMNLAAIGNAYVRDEFRRHKEAPK-YVAGFMAAWTDYLISLGTHLDLDKMSQLSEL Fomme1 ------------------------------------------------------------------- Fusgr1 RLLRAH-RKHLPPDMRILGDEYIKAEFRAHRKVNPAHLIGFLTEWQMYAQKIGDKLDLSKMSQLYEL Galma1 RILRSH-RY-LPSDMRSLGDDYVKSEFRRHKEVNPVYIMGFLSQWKVYLDQMGKRLDFEKMSQLYEL Ganpr1 SIFKLH-RQ-MPPALRYIGDSYVRDEFKRHKEADF-FVEQFMNQWSSYLHDMGRNLPLDKMTQLWAL Gloin1 QILRTH-RL-LPLSLRSLGDDYVKAEFRRHKDVNPIQIVGFIDQWQVYLDKLGKKFDLEKFSQLHVL Hisca1 RLLRVH-RKKLPKDMRLLGDEYVKNEFRAHRNVNPIHIVGFLTEWQLYAQKLGEKLDIDKMSQLYEL Klula1 RILREH-RN-LPTMQRELGDQYVKNEFKLHKSTNPLYIVGFLASWQDYLHMIEGTLSLEKMSQLYEL Lacbi2 RVLRAH-RH-LPLSMRSLGDAYVKSEYRRHRETNPVHIIGFLSQWKMYLDGLGKKLDFEKMSQLYEL Lenti61 RILRAH-RN-LPYEMRSLGDDYVKAEFRRHKETNKVHIIGFLSQWKMYLDQLGAPLDLEKMSQLYEV Malgl1 ------------------------------------------------------------------- Mellp23 RLLRAH-RTSLPPEMRSLGDVYVKDEFRRCRSINPIQIIGFLGQWKIYLDTLGRQLSLEKLSQLFEL Mnele ------------------------------------------------------------------- Monbr ------------------------------------------------------------------- Morel2 QILRAH-RTHLPPQFRILGDGYVKAEFHRHKSVNPLYIVGFIEQWTDYLNHIGRKLDLDKMSQLYEL Mucci2 EILRSH-RS-LPPAMRAMGDDYVKAEFQRHKSINPAHIVGFVSQWQ------GKKLDLDKMSQLYEL Mydma QILKLH-RY-LPNDLKKLGDQYVKEEFRRHKGANQLQAYEFMTEWKFYCDTLGVPLDVNSLSQLFHL Neucr2 RLLRAH-RKYLPREMRLLGDEYVKAEFRAHRSVNPAHLIGFLTEWQLYAQKIGEKLDVEKMSQLYEL Orpsp11 ------------------------------------------------------------------- Pench1 RILRVH-RK-LEPEMRVLGDSYVKNEFRAHRGVNPLHIIGFLTEWQLYAQKLGDKLDLDKMSSIYVA Phybl2 QILRVH-RC-LPPAMRSLGDDYVKAEFRRHKDVNPVHLIGFVSQWQ------GKKMDYEKMSQLYEL Picst3 AILRAHASK-LPTELRPLGDQYVKAEFKAHQKINPLHIVGFLTQWQDYLREIDGKMKLEKMSQLYEL Plicr1 SLLRAH-RS-LPREMRSLGDDYVKAEFRRHRTVNPVHIIGFLSQWKVYLDELGKKLDFEKMSQLYEL Polpo NILRCH-RF-LQEPMRSMGDQYVKTEWRLHKNVDQRIATIFYKKWDEYLQYIGRDLSSHKLSQLKKL Pucgr2 RLLRIH-R-DLPVEMRSLGDLYVKDEFRRCRSINPIQIIGFLSQWKLYLDNLGKKLPLEKLSQLFEL Punst1 RLLRAH-RL-LPYEMRSLGDDYVKSEFRRHRTSNPVHIIGFLSQWKMYLDQLGKKMDFEKMSQLYEL Rhior3 EILRAH-RS-LPPAMRALGDDYVKAEFKRHKEINPAHIVGFVSQWQTYLDTIGKKLDLDKMSQLYEL Rhoto1 RLLRVH-RKVLPPELRIMGDDYVKSEFRRTRSTNPLHIVGFLSEWKKYLDHHGQKLDLETLSQLYEL Rozal11 RILRLH-KQ-LPSEMRLLGDLYVKEEVHRHRNSNKKFVDEFVKEWGKYADILGKKIDLTKLSQLFTA Sacce1 RILRQH-KL-LPGPQREMGDQYVRNEFKLHKDINPLHIVGFLASWQDYLHMIDATLSLEKLSQLYEL Salro ------------------------------------------------------------------- Schco3 GILRGH-RY-LPPEMRSLGDDYVKAEFRRHRKVNPLHIIAFLTEWKLYLDQLGRKLDIEKMSQLYEL Schpo1 RVLRAH-RYHLGAEERALGDEYVKAEFRRHRNVNPLHLVGFLSSWERYADALQEKYSLESLNQLYEL Sorma RLLRAH-RKHLPQEMRLLGDEYVKAEFRAHRSVNPAHLIGFLTEWQLYAQKIGEKLDVEKMSQLYEL Sphar RVMTAN-RT-LPVAMREMGDGYARDEFKKHKNAAS-FVAKFTKGWEEYASMLGRKLTLNSLNQLDAL Spipu1 SIRRLH-KK-LPPALRAIGNGYVKDEFRRHSNAPA-FVPGFMQEWTRYRDMLGRKLELNALNQLHAL Sporo1 RLLRVH-RKVLPAELRVMGDDYVKAEFRRTRSTNPLHIVGFLSEWKKYLDLHGQSLDLESLSQLYEL Stehi1 RLLRAH-RF-LPVEMRSLGDDYIKAEFRRHKEVNPVYIIGFLSQWKRYLDELGRRLDFEKLSQLYEL Tapde11 LILRTH-RTTLPPHLRTIGDAYVKSEFKLHKSTNPIHIIGFLSEWQNYAQMLGKEIDIDRMSQLYAL Thetr NIMRMH-RRVLPVELRMVGDDYVRDEFKRHKAVSPTEVRMFLKEWHGYLKTLGAELALDKLSQLELL Treme1 RLLRIH-RH-LTPEMRFMGDSYIKSEFRLTRKTNPLHIIAFLSQWKVYLDQLGRRLNLEKMSQLYEL Trire2 RLLRAH-RKHLPPDMRVLGDEYVKAEFRAHRNVNPAHLIGFLTEWQMYAQQIGEKIDLQKMSQLYEL Umbra1 NILRAH-RQ-MPPALRAVGDDYVKAEFKRHKDVNPAYIVGFLGEWEKYLDTVGKRIDIERMSQLYEL Ustma22 RIIRAH-RR-LDPDMRAVGDNYVKDEFRRHKNINPLQIIGFLSSWKMYLDQLGQRLDLEKMSQIHEL Walse1 RLLRIH-RT-LPKDFRLMGDGYLRDEFRRHQNINPLQIIGFLSSWKIYLDQMKMNLDLTKLSQLYEL Zygro1 RILREH-RN-LPALQRELGDQYVKNEFRLHRSANPLHIVGFLTSWQDYLRMIDEAMSLQKLSQLYEL [Cluster2553.fasta_al_trimmed; alignment length = 245] Allma1 MDLFSTLPSVFELVAQEQLHNLLSPALRSVLASY-AIRYP-RYLLRVLQFHDELFAL--LMLVVQRHYLRTSKASFAESFYGLK-R-AR-DDLTPSDVSLFCLVVVPYLKQQLHELHRLPATPIYPLVHLLYMFYYSPLLHVLGVEVKRVTSADALEALKVGLPVAIFFSKFLDWFATTDYARQPPPPPRVRTCPLCC-RAVTNAAALP-TGVVYCYPCVRAVQDNG-VCPVTRKPVVGDIRRVF Ashgo11 MDFYSNLPTLFEITSSHEIDGLLKPTFQYLSANA-IQRAPTRARIMLHSRFDELYAL--LKLLLEYYHLDKYNATFIEKYYGLQ-RESV--RLSRGQVVLCEKVAAVYVRDKLDQLHG-----WYPHLKLRYLSATSVLDYLAGIQYARLSQ-PLGVLTSELFPTFIFTVRLLQQWSQQP--TKPAPRPEVVRCPVCR-SAVSNPGVLQ-TGYIACYPCA---KH-G-KCPVMQTPL-RGIRKLI Aspfu1 MEYLPSLPSLFELLAEQQLSDLLPPSLRYLLAIA-THRHP-RYLLRILNSYDEVYAL--LSLIVERYYLRTFGGSFTENFYSLK-R-ERSLKLRSSDVNLFVMVGIPYLKRKLDEGYDLPPRPVYPSVNLAYLFYSSPFLWLIGTRIRRLGAADLLASLRYFLPASIFALKFLEWWHASDFSRQLPAPVVNSACPICL-NTLTNPTACQ-TGYVFCYACIKWESGKG-RCPVTGRRVTEGLRRVL Aurde31 MEYFQDLPSIFELVAQEQLRDLLQPALKYVLSVL-AQRNP-RYLLRIVNRHEEFYAL--IMLYVEQHYLRTRGASFAEDFYGLE-R-RR-SKLRPGDISLLFLVGVPYLRAKAQDYYEALDQTIYPFANMAYMFFYRPWLAWMRVDLRRAGPDVVLDSLRVALPLAIFFVRFLEWWYSPASPARIPPPATLGVCPLCQ-RALANATALP-TGYVFCYVCITHVEKSG-TCPVTLLPALWQLRKIM Batde5 MNFLSHLPFLFELISQDKMRELLQPAFKYILTVA-AQSYP-RWLL-LAYRHDKLYAL--IMAIIDYHRLCRWGGSFTETFYGLC-R-SGTTSLSPSQISLAALILVPLVKSKLDEIHELFNSSGYPYTNIAYMYYYSPWLYLCGLKLKRLSVSDLVGVIQYAIPMGILLFKFLEWWYASDHHKSPPPPDPIHICPLCS-KPRTNSAMLS-TGYAFCYPCINYVSEYG-KCPITFIPLIDNLRKIY Botbo1 MEFFNDVPSLFELVAQEQLRDLLQPALKYVLSVF-AQSYP-RYLLRVVNKHEEFYAL--MMFFVERYYLREHNASFAENFYGLK-R-RR-EKLRPRDISLLLLVGVPYLRAKAHDYYELASATLYPYANVAYLFFYRPWLSWIEVDLRRLGPEDLLQSLKYLLPMSIFFVKFLEWWYAPSSPARIPPPKLIGECPICG-SPIANATALP-SGYVFCYRCAAYVDEHG-KCPVTFTRVLWQLRKVL Botci1 ----MSLPSLFELLSSTQLSSLLPPSLHYLLTVA-THRHP-RHLLPILNSFHELHAL--LFLAIEHHYLTTYSSSFVENFYSLK-R-ERATKLTTKDVNLAVLVGIPYLKRRLDESAEMPPNPVYPSVNLRYLFYSDPFLWLIGTRIRRLSQADLGAGLKLLLPTSIFALKFLEWWHASDFARQLPPPIISENCPICL-QEITTPTACQ-TGYVYCYTCIKWESGAG-RCAVSGRRVVGGLRRVL Caeel SQLASSIPSVFDIIAQENLATSIRPALQHLVKYL-AFFKP-KTFLSVHRNFDEYYII--FDLILQNHYLRNYGASFTENFYSMK-R---NPPNDGRERSLITLVGWPYVENKLNQLYD-----IWPYIKLAYILIHSPWLYFSGVILKHLTPED---IVSRLFAYGLFFVQFLDYMYNTDLAKLPSPPHKMNKCPICL-KKRVNDTALFVSGYVFCYTCIQYVNTYN-KCPVTGCPAVQHLIRLF Canalb1 MEYYSSLPTLFELISANQLESLLSPSLRYILVHY-ASKYP-RYLLQLNNNFDELNLL--LRSFIEWYFLTYWQGTFTENFYGLK-RVSQRRKLSKLQKSLFEVTGVSFVSEKLNYCYE-----IYPYLQLLYLSSPTLLTYLFRINFSRLNQYDIKFVLGTFFPVAIFTLKFLEWWNNSDFSSKLPPPSSL-VCPLCK-KELTNPAIIE-TGYVFDYSCIIDINKGG-RCPITGRRL-EGIRRLI Cangl MSFFSNLPTIFEIVSSQEIDELLPASIRYILTNYWISRYPSWTTLQVNNYFEEWFGV-GVQGLVEWYHIDKYNSTFVDKFYGLQ-RFNN--QLTNGQKVFLQKIILPYISHRLSEVY------LYPLWNLAFLTSMTFLEYLFKIEYTRMTL-PAGLTGSQLFPAFIFMLRVYQWWNTEDLTTKPRPPNAH-ICPICK-DSIENPCVLE-TGYVTCYACA---KHEG-RCPVTGKRLVTGIRRLL Capow -EFAAHLPSFFELVAQDSMMSMLKPALKFLLMVV-TQRHP-GPLAWAIKHHEECYSL--ITLLVQKHYLQVYDASFAENFYGLK-R-VQ---LSSSDRSLFFLAVLPYLKTKLDALFLFAQSQIYPFVHMLYLFYYSPELFLAGLRLRRLTAMDAIDYSKFVVPITIFFFKFLEWWYDSEHYTIPPAPPM-SICPLCL-KQRTNPAVVAVSGLVFCYPCIPYLEQHR-CCPVTLLPATSSLIKIF Catan2 MDLLSNLPSVFELIAQEKLNALLSPALRYILATY-AARYP-RYLLRVLQYHDELFVV--LMLIVQRHYLRVNKGSFAETFYGLK-R-AR-SDLTPQNVSLFALVVAPYLKSKLDEAYALDGSPVYPYVHILYMFYYTPYLHWMGVEVKRLTPTDALEFLKVSLPLSIFFYKFVDWFFTTDYAKQPPPPAPVSMCPVCK-RAIVNPTALP-TGYVYCYPCVRVVDETG-ACPVTLRAVLEQLRRIF Cioin NEVSTALPSPFEVLAQDNLNDSVDPAIKYIVKVL-AQNSP-HRFGWCYVWFDELFAA--VKLLIQQHFLSNYNSTFAEYYYELQ-R------------TLAVLVLLPYIMTKFKSLYL-----AYPLVHFMFAIFHSPFYKLLNTKLFVKSPLDCTQLMTGGVHVGVFALQFVDWWYNSEGNEDPKPPENTKICPLCN-KSRRNETVLQTSGYAFCYTCVKFVNKHG-ACPVTGYTTICHLIRIY CocheC53 MEFLPALPSLFELLSEQQLSSLLPPSLRYLLAVA-TPRYP-RYLLPVLNSFDEVYAL--LMLLVERHFLRTYGGSFTENFYGLK-R-ARAVKLGRDDVNLAVLVGLPWLKRKLDEGYDLRAGAIYPSVNMAYLFYHSPFMWLIGSRIR------------------------------------------------------------------------------------------------- Coere1 MEFMSDMPSLFEIVAQHKMSDLLEPALRHVTSVY-AHRYP-RYLVRALNWHEELYAA--VMLMVERHYLRNYGGSFTEHFYGMK-R-VRGDSMTRGDVSLAFLVGLPLVKSRLDQLYEVAEDTYYPHANVAYMFYNSPWLHILGLHVRRMSAADGLDFLKVLLPLSIFFYRFLEWWYRSDFHKRPPPPLPLSLCAICE-KPRTNPAMVP-SGYVFCYPCIRHILDSG-RCPITLARALEDIRKLY Conco1 MEFMTSLPSIFEYVSQKKLNVLFNPALKYILTIY-AQRYP-RTLLKLLNYYEEFYLG--LNFIIQKHYLELWNATFSESFYGLR-R-LRAPDLTNREKSLLVEVGGPYIKCKLDQAYEYEDYSVYPYLHIGYLYYPSPFYHVLNLMVRRMTMDDLVDILKVALPMSIFFFKFVEWWYSSPHSQQ--PPAPLSLCPLCL-RQRTNPTIIP-SGYVFCYPCISYLEEFS-RCPVTWSQTQKQLRRIY Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci MEFFNDLPSLFEVIAQEQLKDLLQPALKYVLAVF-AQRYP-RYLIRIVNRHEEFYAL--IMLVVERHYLTKHNASFSENFYGLK-R-RR-ERLRDREISLLFLIGIPYIRAKAHDYFELTDQVVYPWLNIRYLFAYRPWLSWIGVDLRRLGPEDLLDSLRLLLPTAIFFVKFLEWWYSPGSPARIPPPRMLGICPICR-KEINNATALP-SGYVFCYRCADQVEKQG-RCPITLLPAVWQLRKVL Croqu1 MVSQSEIPSFFELTAQDQLRDLLGPVSRYVLSVF-AQSHP-RYLLKIVNRHDECFAL--LMLLVERYYLKNWGGSFSEHFYSLKRR-RR-DRLTPSQVCLFGLVGIPYLRSKARDLYEIRTSAFYPYANIQYLFYWKFFDAWLEVDIRRLSGEDSLESLKVVLPCSIFIFKFLEWWYSSSNIRRIKPPASLGHCPICR-SILVNSTAFP-SGWVCCYKCASYVIDFG-RCPVTCYPALADLRKII CryneH991 --MIQPVPSLFDLLAQEQLRDLFHPVLRYILSYL-AQRYP-RYFLRLLNHHEETFAL--LLLIVEKHHLERHNASVSEHFYGLR-----ATNLTRKQRILIFIVGLPYVRARAQDYFE-----LYPYLNIAYLFYWRPWYRLLNLRITRTTTSS---SLPPLLPPLLLTLKLSQWWYSPSSPRAILPPRAVGICPLCN-KAWANPAILP-SGWVICWKCGKKMKRKG-RCPITDIYVPGGLRRVL Crypa2 MEFITALPSLFELLSEQQLSSLLPPTLRYLLVHA-THRSP-RYLLPVLNSFDETYAV--LMLLVERHYLLTRGGSFTEHFYGLK-R-EKTLALRTADVNLAVMVGIPYLKRKLDEAYELPPNPIYPSVNLAYLFYHNPFLWLIGTRVRRMTGADVLGSLSVLLPTSIFALKFLEWWYASDFARQLPPPIVSELCPICR-DDITTPTACQ-TGVVYCYACIKWESGES-RCAVTGRRVTEGLRRIM Debha1 MEYYSSLPTLFELISASQLESLLSPSLRYILVHY-ASKYP-YLLLKVANNFEELNLF--FRTFIEWYFMSYWQGSFTENFYGLK-RVSQRRSLSGLQRSIFEITGVSYLSEKFNYWYE-----LYPILQLLYLSSPTLLTILFKINYSRLNQYDINFILGTFFPVAIFMLKFLEWYSNSNFALKLPPPSSL-TCPLCK-DEISNPAIIE-TGYVFCYSCIIDVNKGG-RCPITGKKL-EGIRRLI Dekbr2 MEFYSNLPTIFEIISAEELENLLSPSIRYVLAYY-ATRYP-RHLIKILNHFGSLNLL--IRGLIEYRVLRTWNSTFIERFYGLK-RVNRLRRLKKKQITLLELLLVPYIKEKLDVLYE-----LYPKVEILFISSASLLQQLFGIQYARFSSYDLLFGADTVLPASIFILKFLEWWNSSDAVSNPKSPSLL-TCRICH-EAINNPAIIE-TGYVFCYPCI---STGG-RCPVTGKKL-TGIRRLI Dicdi -MFMFNFPSFFEMLNQHQMMPSFKPALKYIFTVL-SQRNP--KFRYIVNYYDECFYS--LLLLLEYHYLKYYEGSFSENFYNLK-R-IKNTMIQDSDRSLIYLVLIPYFKGKLDEYYKIVNGNVYPFISLLYLYYYTPFFHFQNIQLKRLNHKDILDYSKYILPLSVFIFKSLEWWY-SENRISPTPPTP-RLCPLCL-KERTNPTICG-SGFVFCYPCIGYVNEHS-KCPITFLPTTEQLRKIY Dmel MAEAANVPSIFEISASETLDNLIYPALSKIFDYF-GLRLD-FKLWGSLRIQEELSPL--LTWLLQYLYLRKRASSFGESFYGLQ-R---GDLLNRRQQSATLLTFMPYVERKLRTRIT-----------FFYLVNHSPIFRLLGLTLRY-----------------AFFLQFVQWWYSNDQRRKINPEAM-GECPVCL-LSIQTPTACSVSGYVFCWKCISHMKEHG-TCPVTHYPILDDLVRIY Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 MEFVTALPSLFEVLSEQQLNALLPPTLRYLLTIA-THRHP-RYLLRILNSFDEIYAG--VMLLVERHYLRTRGGSFTEHFYGLK-R-EKTLKLTTRDVNLLVIVGIPYLKRKLDESYEMPDNPIYPSVNVAYLFYHNPLLWLIGTRIRRMSGADVLSSLSILLPTSIFALKFLEWWYQSDFAKQLPPPVISALCPICI-DEIVTPTACQ-TGVVYCYTCIKWESGQG-RCAVTGRRVTEGLRRIM Galma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 ASFLAATPSYFELSTLEDIRDRLQPAMRYFLTVF-APRYP-RLLLPLVNRHEELYAT--VFGFIEAYYLWEHDGSFEENFYGLK-R----EKLSSRERSLATLIAVPYVRSKLQELYERGQSPAYPYVNVLYMYYFSPWLYLLGVEIKRL---DVLEALKVALPLSMFALKFLEWWYQSGFAKKPRPPPRIEQCAICN-TPRTNPAMLP-SGYVFCYPCIKFVEENS-CCPVTRIRTTTEIRRLY Gloin1 MEFMSDIPSLFELLAQEKLRALIQPAVRYILSVY-AQRYP-RYLLRIVNRFDEFYAV--AMLLIERQYLKNYYASFAESFYGLK-R-IR--KLRNSDMSLFFLVGIPYIKTKLDDLYE-----LYPWLNVLYLYCYTPWLSLMGIEVRRMSAQDLLNFLKSLLQMSIFFSRFLEWWYSSEYARRVPPPDIINVCPICT-NLLTNTTALP-SGYVFCYPCISYIEDYE-RCPITLIKVINELRKVY Hisca1 MEYMSALPSLFEILSEQQLSALLPPSLRYILAVA-THRHP-RYLLRALNSFDELYAL--LSLLVERYYLRTFGGSFTENFYSLK-R-ERTLKLRSSDINLAVMVGIPYLKRKLDEGYDLPHNPVYPSLNLAYLFYSSPFLWLIGTRIRRLGPADLLGSLKIFLPTSIFALKFLEWWHASDFSHQLPPPVTSSPCPICL-RPLKNPAVCQ-TGYVFCYSCIKWESGKG-RCAVTGRRVSEGLRRVL Klula1 MDFYSNLPTLFEILSVNEVKKLIKPTLRYIFSIYLQYRGPTRWLLKIFNKFDFIILV--IKSLVEYRHYKTTGATILDKFYGLK-R---GIWLN--DC-------FEYVSDICEQYHE-----YYPKLQLKYLRYQRYQEPEEGIASRKLTLSESTMFLDKLFPSFLVMIRIL---QIINQRPEPKPPVL-DVCPLCG-EEITEPAMIS-SGYVANLECAKWVSTEN-TCFATGVPI---IRKLL Lacbi2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 MDVLANIPSFFELIAQKQLSDLLKPAIRYVLTVL-AQHYP-RYLLRIVNRFDELYAV--LMLAVERHYLRTWNASFTEHFYGLR-R-RRTRQLRDREVSLLFLVGLPYLEAKLSDYWE-----GFPLVQIKYLFYWRPWLAAMRVDVRRAMGNEILDALKYALPASIFFFKFLEWWYSPNN--RLGPPVVSNSCPLCGAMPIQNPCALP-TGFAFCYRCADYVDKWH-VCPVTQIDLIEQIRRVL Mellp23 ---MNILPNFFELIAQDQLRDLLSPVTRYVLSVF-AQSHP-RYLLRIVNRHDECFAL--LMLFIERYYLKNWGGSFAEHFYGLK-R-RR---LRTKHISLFCLVGIPYLRKKARDLYEIDPNALYPYTNLQYLLYWRPFEAWMKLEIRRLSGQDTLESLKVALPCSIFAFKFLEWWYSPSNIRRIKPPVSLGHCPICR-SVLVNSTAFP-SGWVCCYKCASYVSDFG-RCPVTWYPTLADLRKII Mnele M------PSLLTLISADEMNKALYPAFLHLTKCMGVSSLT----------SDVLYLK--LSAALQSYYLYHYNSSLAEHYWGVS-R---SSHSSSGQLVLKVLILGPFLNQKLRNIHN-----VYPYVNLGYFLKFSISNSLLNISYQS-----LRSVIELLFPISMFYVQFIKQWSSIEGVSPPPPPYKKDLCPICG-ERLRIPTAMPTTGVVYCYVCITHVQSSG-SCPVSHLHVTADLIKLN Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MEFMSNLPSLFELIAQDKMREMLEPALRYVIAVY-AQRYP-RYLIRIVNRYEEFYAV--LMFFVERHYLREYGASFAENFYGLK-R-VRSNKLRERDISLLFLIGLPYVKCKMDEYYELTGQPGYPFVNIGYLYYYSPWLRLIGIEVKRMSAADSLDFLKVLLPMSIFFFKFLEWWYQSDYYRKVPPPARVNICPICL-KTITNPTALS-SGYVYCYPCAKQVEDHE-RCPVTLMHCTDDLRKLY Mucci2 MEFMSALPSLFELVAQEKLKELLQPAVQYVLAIY-AQRYP-RLLLRVVNNHEEFYAA--LMLLVERHYLKEWGGSFAENFYGLK-R---SPALTSREISLLVLVGLPYVKCRLDLLYQLANPEVYPIINVAYLFYYTPWLHLLGLEVKRMSMNDVIEFLKVLLPMSIFFFKFLEWWYSSEFSRGVPPPEKINTCPLCLSSPINNPTALP-SGYVFCYTCAHYVEEHG-RCPVTWIKVAEDLTKLY Mydma MAF----ASLFDVTAEDSLRLSLKPAWVYFCNVL-KMRYP-VLLKNLLKYSDEIFAI--LIMVLEEYSFRRNSGTVTECFYQLK-R----NSFRFRHVSLTSVVLLPYISDKLQNYYD-----LYPILLIQYLFHPSPILRMAGIQLKYVKVSDTASIVMKIAPLVFYSLQFVDMFYDKETGVSLPFPSAPKQCPLCQ-LPHTNPTTIVSSGFVFCYACLRYIEKHK-CCPITYRPCFTDMIRIH Neucr2 MEFVTALPSLFELLSEQQLASLLPPTLRYLLTVL-THRYP-RHLLRILNSFDELYAL--AGLLVERHYLKTRGGSFTEHFYGLK-R-EKALKLSDVDINLAVMVGIPYLKRKLDEAYEPPAKGVYPSLNLGYLFYHNPFLWLIGTRVRRMNGADLMGGLSLVLPTSIFALKFLEWWYASDFAKQLPPPTVTDMCPICE-DEIQTPAACQ-TGVVYCFSCIKWESGEG-RCAVTGRKVTEGLRRIM Orpsp11 ----MNVPSFFELINQEKMDELIAPAIDYILSIY-AQRYP-RYLLKIANRSQEIYSI--IMIFIERYYLKKYNASFTESYYSFK-R-VP-TDLTKKQISILFLVGVPYIRKKLSMLYE-----------EQYNF--------------------------------------------------------------------------------------EENEEKD------------------ Pench1 MEYLPSLPSLFELLAEQQLSDLLPPSLRYLLAVA-THRHP-RYLLRILNSYDEVYAL--LSLIVERYYLRTFGGSFTENFYSLK-R-ERALKLHSADINLFVMVGIPYLKRKLDEGYDLPANPVYPSVNLAYLFYSSPFLWLIGTRIRRLGAADLLGSLRYFLPASIFALKFLEWWHASDFSRQLPAPVVANTCPVCM-GALVNPTACQ-TGYVFCYVCIKWESGKG-RCPVTGRRVTEGLRRVL Phybl2 ---MSALPSLFEIVAQEKLRELLQPAVQYLLAIY-AQRYP-RLLIRVVNNHEEFYSV--LMFFIERHYLKEWGASFAENFYGLK-R---TPPLSSKEISLLILVGLPYIKCRLDLFYQLADSTVYPYINIGYMFYYSPWFHLIGLQVKRMSMSDLIEFLKVLLPMSIFFFKFLEWWYSSEFARGIPPPKNTNTCPVCLSQPIPNPTALP-SGYVFCYTCAHYVEEHN-RCPVTWQRTVQDLTKVY Picst3 MEYYSSLPTLFELISASQLESLLSPSLRYILVHY-ASRYP-KYLLRINNRFDELNLV--LRSFVEWYFVQYWHGSFTENFYGLK-RVNQRRALTSLQKSVFEITGTAYVSEKLNYCYE-----IYPYVQLMYLSSPTLLTYLFRMNYARLSQYDVSFILGTFFPVAIFSLKFLEWWNNSDFASKLPPPGLV-TCPICK-KELTNPAIIE-TGYVFDYACIIDINKGG-RCPVTGRKL-EGIRRLI Plicr1 MEFFNDIPSLFELVAQEQLRDLLQPALKYVLAVF-AQRYP-RYLLRIVNRHEEFYAT--IMLFVERHYLRKHNASFSENFYGLK-R-RR-ERLGEREISLTFLVGIPYLRAKAQDYFELTDQVIYPWLNVAYLFFYRPWLKWIGVDLRRLGVEDLLDSLRLLLPTAIFFVKFLEWWYSPGSPARVPPPRMLGQCPLCR-GPINNATALP-SGYVFCYKCAEHVEKQG-RCPVTLLPAIWQLRKVL Polpo LMFLFNFPSFFEMFAQHQMMPSFKPALKYIFTVL-SQRNS--KFEIIVKYHDEFFYS--MLLLLEYHYLKYYEGSFSENFYNLK-RSVKTKPMTAKDQSILYLVILPYIKTKLDEFYK-----IYPTISLLYLYFYTPFLHLQRIVLKRLTHQDILDYTKFILPASVFLFKSLEWWY-SENRASPPPPSQ-TQCPLCL-KERTNPTICG-SGFVFCYPCISYVQQHQ-KCPITFIPATEHLRKIY Pucgr2 MD-----PTFFELVAQDQLRELIGPVIRYITSVF-AQRYP-RYLIKLLNHHDEVAAM--ISWFIQSISQNCSGGSFAENFYGLS-R-RR-GRLAPHDVSLIFLVAIPYLRAKAAGLHETDDSRSYPYFILRYLFYWRASQAYTGIEIRRTSAHDFFESLKVLLPGSIFFFKFLEWWYSSSNTSRIQPPVPLGHCPICR-TKLSNPTAVP-SGWVYCYKCIPYVVEYQ-QCPVTHFPTLTNLRKII Punst1 MEFFNDVPSLFELVAQEQLRDLLQPALKYVLSVF-AQRYP-RYLLRIVNRHEEFYAF--IMFFVERHFLRTHGASFSENFYGLK-R-RR-ERLRNRDISLVFLIGLPYLRAKAQDYYELTEETIYPWANILYLFFHRPWLAWTGIDIRRLGLDDLLDALKVLLPTAIFFIKFLEWWFSPSSPARVPPPKLLGMCPLCE-QPIANATALP-SGYVFCYRCAGHIEQHH-SCPVTLLPAMWQMRKVL Rhior3 MEFMSALPSLFELVAQDKLKELLQPAIQYVLAIY-AQRYP-RLLLRIVNNHEEFYAI--MMLLIERHYLKEWSGSFAENFYGLK-R---TPSLSTKDISLLVLVGLPYIKCKLDLFYQLEDNNVYPIINIAYMFYYTPWLHLIGIEVKRMDMNDVIEYLKVLLPMSIFFFKFLEWWYSSEFSRSVPPPEKINTCPLCLNNPINNPTAMP-SGYVFCYTCVHYLQENG-RCPVTWIRVPKNLTKLY Rhoto1 MEYLGPGPSIFELAAQDQLRDLLSPVVRYVLSVF-AQRNP-RYLLRIVNHHDSLFAL--CMYFVERHYLVTHGGSFAETFYGLK-R-RK-DRLGRKEVSLAFLVLMPYLKTKATDLYELRNASSYPYVNLRYLFYWRPWFRLLGIEVRRMGQEDALDSLRLLLPLSIFGFRLLEWWYSPTGGAGAPPP---GKCVVHG-GPVENPTALP-SGWIGCYKCLEEVEDPA-AGPKTGEWVVGRLRRIM Rozal11 -MFITSK----------------------------SKSYS------------------------------------------------------------------------------------------------------------------------------------------------VPPPV--GKCPVCG-KDYENEVAIP-SGVIGCYKCIGFVREKG-YCPVTQIRTEEEIRRLY Sacce1 MSFYSNLPTIFEIMSSQEIDSLLPASIRYLLANHLVANFPNRYTLRLNKYFFEWFQA--IKGFVEWYHLKTYNSTFIDRFYGLQ-LFSS--QLNQQQKIFLEKIILPYITAKLDE--------IYPFIKLLFLTSVSLLQYLFKIEYT-TVR-PLTFMGSQFFPTFIFVLRVYQWWTTQDMTTKPRPPFS---CPVCE-KTVQNPCVLE-TGYVACYPCA---NNEG-HCPVTNKKLVTGIRKLL Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MEFFSGAPSIFELVAQEQLRDLLQPALKYVLAVF-AQRYP-RYLIRIVNRHEEFYAL--IMLIVERYYLRKHNASFAENFYGMK-R-RR-ERLRNREISLFFLVAIPYIRAKAHDWFEDGSETLYPWANVAYLFYYRPWLKWIGVDLRRLGPEDLLDSLRLLLPTAIFFVKFLEWWYAPGSPARVPPPRMLGTCPVCR-QSINNATALP-SGYVYCYRCAEEVEERG-RCPVTLLPAMWQLRKVL Schpo1 -------PSLLEVLQVQQVEKLISPSLRFILA-YFTHRYP-RFLLRAYNSFDGIYLL--VKLLLEKSQLKKWNATSVERRFQLK-R---ATSLNGIDVKLFLTYCIPYLLEKCESLTT-----FYSKIKLYYLLRQRVIYNVENIHSRK--LIS-TSIADHSMEGFLIIIQLIDWWQSNNYESHLAPPKL-DICKICG-EKIKNPAVLS-TGFVFCYPCIVWLQRHPFKCPVTNLELGESFWRLM Sorma MEFVTALPSLFELLSEQQLASLLPPTLRYLLTVL-THRYP-RYLLRILNSFDELYAF--AGLLVERHYLKTRGGSFTEHFYGLK-R-EKALKLSDADINLAVMIGIPYLKRKLDEAYEPPAKGVYPSLNLGYLFYHNPFLWMIGTRIRRMNGADLMGGLSLVLPTSIFALKFLEWWYASDFAKQLPPPTVTDLCPICE-DEIQTPAACQ-TGVVYCFSCIKWESGEG-RCAVTGRKVTEGLRRIM Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 MEYLSNIPSVFELIAQDKMRDLLKPALRYVLAVY-AQRYP-RHLLRLVNRHDEVFAI--LMLLIEQHYLREWNASFAEHFYGLK-R---LEHLSSSQISLVLLVALPYAKTKLDELYELEEP-TYPYINIGYMYYYSPWLHLCGLQIRRMGAKDGFDFLKYALPMSIFFFKFLEWWYTSEYHKQPPPPKPLSICPLCT-KQRTNPTMLP-SGYVFCYPCIKYVEEHE-RCPITFLPTTEELRKIY Sporo1 MEYLTDLPSLFELAAQDQLRDFLSPVVRYVLSVF-AQRNP-RYLLRIVNSHDELFSL--AMLLVERHYLVHYSASFAEHFYGLK-R-RK-DKLGRKEISLVFLILLPYLKTKAQDWFELRNNQSYPYLTLRYLFHWRPWFKLMGIEVRRMGQEDALDSLSVALPMAIFGFRFLEWWYSPTGGAGAPPPRRRGVCPIHG-GKIENPTALP-SGVVACYKCLEAREESL-AK---GERVVGKLRRIM Stehi1 MEFFNDIPSLFELIAQEQLRDLLQPALKYVLSVF-AQRYP-RYLLRIVNRHEEFYAL--IMLFVERHYLRQHNASFSENFYGLK-R-RR-ENLRRREVSLLLLVGLPYIRAKAQDYFELTEETLYPWLNVAYLFYYRPWLSWIGVDLRRLGIDDLLDSLKLLLPTTIFFIKFLEWWYSPSSPARIPPPALLGKCPICG-EGIKNATALP-SGYVFCYRCAEEVEKSG-RCPVTLLPAVWQLRKVL Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr -------PTVFEVWAQRALSTTLPAGCAWAVDYV-SGKVS-SATGGRVAGVEALYAAWALRALIESHHMVLHHGSFAESFYGMRRR---CSDRSLSLIILAALIALPIVKAAADEWYELPERAIYPALHVLYLNYASPVLHLLGQQLVRSSAAEALDALKYAFPASVLGHRMVSWWSSRD----PAPP---GGCAICG--------ALG---------------------GVSGDPGADG----- Treme1 MSSSEPLPSLFELLAQDQLRDLLHPVVRYVLTYF-TQRYP-RYFLRALNHHEEVFAL--LLLIVERHHLSKHNASISEHFYQLR-----RNILSRKQRLLVFLVGLPYIRARLQDHFE-----LYPYMNVAYMFYYRPWHRWLGVKVRRITPDD---WIPPLLPTLLLALKAAEWWYSPSSPRTILPPRPLGTCPICN-KKWQNPAVLP-SGWVVCWRCGVSRRKRG-RCPITGMMVSSELRRVL Trire2 MEFITALPSLFEVLSEQQLNSLLPPTLRYLLTVA-THRHP-RYLLRILNSFDELYAL--LMLAVERHYLRTRGGSFTENFYGLK-R-EKTLKLTTRDVNLAVLVGVPYLKRKLDESYDMPDNPVYPHVNLAYLFYHNPLMWLIGTRIRRMTGADAMSSLSMLLPLSIFALKFLEWWYQSDFAKQLPPPIVSSLCPICE-GEIVTPTLCQ-TGIVYCYTCIKWESGQG-RCAVTGKRVTEGLRRIM Umbra1 MEFMSALPSLFELIAQEKLREMLQPAVQYVLAVY-AQRYP-RFLIRIVNKHEEFYAG--LMLLIERHYLKEWGASFAENFYGLK-R---SQKLSTKDISLLFLVGLPYIKSKLDLLYSLNDPSVYPVVNIGYLFYYTPWLRILDIEVKRMSMDDMIELLKVLLPMSIFFFKFLEWWYASEFARGIPPPEKVNTCPLCLTRPINNPTALP-SGYVFCYTCARYVEDHG-RCPVTWTKITERLTKVY Ustma22 MDVLTSVPSFFELAAQSQLSELIKPAVRYVVAVL-AQRNP-RYLLRIVNWFDEVYAL--LMTAVESHYLRVWGSSFSENFYGLR-R-RKTESLGKREISLLFLVGLPYLRAKLDDIWEFQDSSAYPYFKVRYLFYWRPWLSLMRVDVRRVGPNDLFEALKYGLPASIFLFKFLEWWYGADNPRRLDAPATLNSCPLCGAMPINNPAVLP-SGYVFCYTCANYVEQHA-TCPVSSISVKDALRKVL Walse1 MDY--QLPSLFELFAQDELTDLLQPAVKYVLSIL-ATRYP-RYLLRLVNKHEEFYAL--IMLIVESHYLRTQNASFTESFYGLK-R-RNFDKLTKGQISLVFLVGVPYLRTKSKELYD---EVVYPYANLRYMFFYRPWLQWMNIDIRRATLADLLSSLKTALPVTLFILKFLQWWYSSQSPRLTPPPAKLGIDPLTG-EPLENATLTP-TGYVYSFKSLDYVEKHN-RCPVTLKPVVTQLRKVL Zygro1 MSFYSNLPTIFEIVSSQEIDALLPASVRYILTNYWIARHPNKITLAINNYFQEWFQV-LLKGIVEWHHIKEYNSTFVDRFYGLQ-RFNC--QFTKGQKVFIQKVIVPYLKDRLDE--------VYPVFKLLFLASVSFLEYLFKIEYTRAVL-PSAYLGSQFFPAFIFMLRVYQWWTTQDLGAKPRTNNK--DCPICH-QRIQNACVLE-TGYAACYPCA---NNEG-KCPVTGKKLVTGVRKLL [Cluster2556.fasta_al_trimmed; alignment length = 101] Allma1 RSRGCHLVTDEIPDLRKFKVGLANIFIQHTSASLTINEN-CDPDDMEMMLNTHTDEGAD--DMPAHVKTTLVGPSLTIPISNGNLALGGIWLCEHRIVVTL Ashgo11 ----------------------------------------------------------------------------------------------------- Aspfu1 RSRGSYLITDEVPEIRNYKVGMLNLFVQHTSCALSLNEN-WDEDDMSDALDRHSAEGED--DMPAHIKSALVGASVNIPITNGRLATGGIWYLEFRVVATI Aurde31 ---------------------------QHTSAALTINEN-YDPGYMNDALDRHVDEGPEYHRRTSHVKTSLVGNSIQIPITDYRLNLGGIYLTEFRIVATI Batde5 ----------------KCQIGLANIFLQHTSASLTINEN-CDPDDMEMSLNIHTDEGSD--DMPGHVKSSLFGCSLTIPVTNSALNLGGIWLCEHRVVITV Botbo1 RSKGCHLVTDEIQGLRGVSIGILHIFIQHTSAALTVNEN-ADSDDMSMALDLHVDEGPD--DWVSHTKATLVGPSIQIPITNGRLNLGGIYLTEFRVVATI Botci1 KSRGSYLVTDHIPEIKNYKVGLLNLFIQHTSCAISLNEN-WDEDDMSDALDRHSAEGLD--DMPAHIKSALVGASVTIPITNGKLNTGGIWYLEFRVVATI Caeel ----------------------------------------------------------------------------------------------------- Canalb1 KSKGCYLITDDVPQIKDYEMGILNLFLQHTSAALSINEN-WDPDDLDKSLDLHDAEGPD--DSVSHIKSSTIGVSLSIPITNGKLSLGGIYLCEFRIVATI Cangl ----------------------------------------------------------------------------------------------------- Capow RRRGCHLITSEVEAVARIEIGLCHLFLQHSSASISINEN-ADPDDMETVLNVHDAEGPD--DMPAHVKSSLFGVSVTVPITNGRLNFGGVHLIPLQVTVTA Catan2 RSRGCHLVTNEIADLRKFKVGLANVFLQHTSASLTINEN-ADPDDMEMMLNVHTDEGPD--DMPGHVKCSLFGAALTIPITNGRLNLGGIWLCEHRVVVTL Cioin ----------------------------------------------------------------------------------------------------- CocheC53 RSRGCYLITDHIPEIKQYKTGLLNLFIQHTSCALSLNEN-FDEDDMGTALDLHDAEGSD--DMPAHVKSALIGASVTIPITNGRLNTGGIWYLEFRVVATI Coere1 RSKGSYLITNEIKEIRQYKIGMCNIFLQHTSASLCLNEN-VCKEDLTMALDRHTDEGPD--DMPGHAKSAIMGVSLDIPISNGQLALGGIYLCEHRVVITM Conco1 ------LITSEI---------LANFFIQHTSASLTINEN-CDPDDMEMMLNIHTDEGPD--DMPGHVKSSLFGASLNIPISNGRLNLGGIWLCEHRIVVTL Conpu1 RSKGCHLVTQEVPGLENVQAGMLFLFIQHTSAALTVNEN-FDPDDMDMALDVHTDEGPD--DSASHTKSTLVGSSISIPITNGRLNLGGIYLTEFRVVATI Copci RSKGCYLVTDEVPGLKDVQVGMLFLFIQHTSAALTINEN-FDKDDMDMALDRHTDEGPD--DSVSHTKASLVGSTISIPITNGALNLGGIYLTEFRVVATI Croqu1 ------VVTDEVDGLKNCDIGVAHFFIQHTSAALSINEN-YDPDDMDMALDRHTDEGPD--DSVSHTKASLIGSSISIPITKGKLNLGGIYLTEFRIVCTI CryneH991 LEKRRH-------------------RYIHSS---LLAHF-CWLDDMDMALDEHTDEGPD--DSVSHLKTSLIGNSITVPISKGKLVLGGIYLAEFRVVATI Crypa2 KSRGSYLITDHVPEIKNYKVGLLNLFIQHTSCALSLNEN-WDDDDMSDALDRHSAEGPD--DMPAHIKSALIGASVTIPIRDGKLATGGIWYLEFRVVATI Debha1 KTKGFHLVTDEIPEIRDYKIGQLNLFIQHTSAGLTINEN-YDPDDLINIFDIHILEGLN--DAKSHGQATLTGLNVTVPISNGKLAFGGIYLAEFRIVATI Dekbr2 RARGCYLVTDEVPQIRSYKVGMVNLFLEHTSAGLSLNEN-WDPSDMTTALNDHVDEGAD--DMSGHAKSSIIGVSLSIPITNGRLALGGIWLLEFRCLATI Dicdi ----------------------------------------------------------------------------------------------------- Dmel QHRGVHLVTEEIPELAHFSVGLCHMQILHTSASLALNES-WDPDDMEMMLNRHSCEGPD--DMPAHVKACFLGSSLTIPITDGKLSLGGVWLCEHRLVITL Enthi KRRGSHLITNEVQQLKTIKVGMCNVFLMHTSASLCINEN-CDPSDMETIFNEHCMEGDD--DMPAHAKCSMFGCSLNIPIREGDLCLGGIYLNEHRIVVTL Falba ----------------------------------------------------------------------------------------------------- Fomme1 RSKGCHLITDEIPGLHDVKIGILYLFIQHTSCGITVNEN-FDPADMDMALDQHLAEGSE----ASHTKTALVGTSVQIPITDGRLNLGGIYLTEFRVVATI Fusgr1 KSRGSYLITDQVPEIRDFKVGLLNLFVQHTSCALSLNEN-WDSDDMSDALDRHDAEGPD--DMPAHIKSALIGASVTIPIKDGKLATGGIWYLEFRVVATI Galma1 RAKGCHLITDEILGLEGVKVG---LFFQHTSAALTVNEN-YDQGDMDMALDRHTDEGPD--DSVSHTKATLVGSSITVPITDGRLNLGGIYLTEFRVVATI Ganpr1 KRRGCHLVTNDIPDLAQFSVGMANVFLQHTSASLTINEN-YDPDDMEMMLNTHTMEGSD--DMPGHVKSSLFGVSLNIPVRDGKLALGGIWLCEHRVMVTV Gloin1 KSRGCHLITREIPEIEEYEIGMANIFLQHTSASLCLNEN-ADPDDMEMALNVHTDEGPD--DMPGHVKCALVGASLNIPITKGKLNLGGVWLCEHRVVVTL Hisca1 ----------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------- Lacbi2 RAKGCHLVTEEVAGLLGVQVGMLFLFIQHTSAALTVNEN-FDKDDMDMALDRHTDEGPD--DSVSHTKASLIGTSISIPITNGQLNLGGIYLTEFRVVATI Lenti61 RNKGCHLVTDEVPGLRGVQVGMLYLFIQHTSAALTINEN-FDRGHMDMALDRHTDEGPE----VSHTKTSLIGTSICVPITDGRLNLGGIYLTEFRIVATV Malgl1 RGKGCHLVQSEVDMLRGVQVGILTLFIQHTSAALSLNEN-FDRDDMDMALDRHTDEGPD--DSASHTKASLIGPSLTIPITQGHMNLGGIYLCEFRLVATV Mellp23 CEGRCHL---EIAHTIFHQIGVAHFFIQHTSAALSINENQCDSEDMDMALDKHTDE----HFYTNHQRE----------IEPGNLA---------R----- Mnele KGRGCHLITEHIKELEEFKVGLCHIILLHTSASLTLNEN-WDPNDMEMMLNSHTCEGPD--DMPAHVKSTLIGSEITIPIHHGKLTLGGLWLCEHRIVITL Monbr HA-GCRLMTREVPAVDH---GLLHVAVLTAGVGITLNEN-ADPTDVDDAVPEHTYEGPD--DMPGHVKSTLIGTDV--------LRLS-LHLIEPRVAGAI Morel2 KKRGCHLVTREIPELKQFSVGMANIFLQHTSASLTLNEN-ADPDDMEMALNIHTDEGPD--DMPGHLKSSLMGVSLNIPITKGRLNLGGIWLCEHRIVVTM Mucci2 RRRGCHLVHKEIPELKNYKIGMANVFLQHTSASLMINEN-FDSDDMEMGLNIHTAEGPD--DMPGHLKSGIVGVSLNIPITSGKLNLGGIYLCEHRVVVTL Mydma KSRGIHKITN-IPFLNKIKIGTCCLLLKHTSASLSLNEC-WDDDDMEMILNTHTQEGPD--DMPAHVKTSLIGASITIPITDGKLNLGGIWLCEHRLVVTV Neucr2 QSRGAYLITDIVPEIKQYKVGLLNLFIQHTSCALSLNEN-WDPDDMSDTLDRHNDEGPD--DFPAHVKSSLIGTSVTIPITNGKLATGGIWYLEFRIVATI Orpsp11 ----------------------------------------------------------------------------------------------------- Pench1 RSRGSYLITDHVPEIRDYKVGMLNLFVQHTSCALSLNEN-WDDDDMSDALDRHSAEGED--DMPAHIKSALIGASVNIPITNGRLATGGIWYLEFRVVATI Phybl2 YPKGCHLVHQEIPEIKQYKVGMANIFLQHTSASLMLNEN-CDPDDMDMALDIHTDEGPD--DMPGHLKTGMIGVSLNIPITNGKLNTGGIYLCEHRIVVTL Picst3 RSKGTYLITDEVPQIKSYEVGILHLFLQHTSAAISLNEN-CDPDDMNHALDIHADEGPD--DMPGHVKSTVVGVSLSIPISNGRLATGGIYLLEFRIVATI Plicr1 RSKGCHLVTEEVPGLKDVQVGMLFLFIQHTSAALTINEN-FDKDDMDMALDIHTDEGPD--DSVSHTKTSLVGTSISVPITGGRLNLGGIYLTEFRVVATI Polpo ----------------------------------------------------------------------------------------------------- Pucgr2 RPKGCHLVTEEVEGLKNCDIGVAHFFIQHTSAALSINEN-YDSDDMDMALDRHTDEGPD--DSVSHTKASLIGSSISVPVTKGQLNLGGIYLTEFRVVCTI Punst1 RGKGCHLITEEVPGLRDVKIGMLYLFIQHTSAALTINEN-FDPDDMTMALDIHTDEGPD--DSVSHTKTSLIGPTITIPITDGRLNLGGIYLTEFRIVATI Rhior3 RKRGCHLVHREIPELKTMKVGMANVFLQHTSASLMINEN-ADPDDMEMGLNIHTDEGPD--DMPGHLKSGLVGVSLNIPISDGRLNLGGIYLCEHRVVVTL Rhoto1 RPKGCHLITDEIDKLKNTKIGILHLFIQHTSAALTINEN-CDPDDMDRVLDDHVDEGPD--DSVSHTKASIIGPSIQIPIGNGRLMTGGIYLTEFRVVATI Rozal11 ----------------------------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------- Schco3 RSKGCHLVTSEVDGLKDVKVGMLYLFIKHTSCGLTLNEN-YDPDDMDMALDVHTDEGPD--DSVSHTKSALIGTTVTVPITDGRLNLGGIYLCEFRVVATI Schpo1 RSKGFYIITNDLPELKSFSSGTVNFFIQHTSAALTINEN-WDADDMNDILDRHTAEGLD--DMPAHVKSSLIGPSLTVPITNGKLSLGDIQLAEFRIVCTI Sorma QSRGSYLITDIVPEIKQYKVGLLNLFIQHTSCALSLNEN-WDPDDMSDALDRHSDEGPD--DLPAHVKSSLIGTSVTIPIKNGKLATGGIWYLEFRIVATI Sphar RGAGTYEFTKDV-AKSGVKVGLLTLFVQHTSCSLLISEN-ADPEDMKNFMSTHTYEGPD--DMPGHIKNALLPVSISIPVTNGRPCLGGIFLFEHRIVAHL Spipu1 KPRGCHLVTQDVPELKSFKVGMANFFLQHTSAALTINEN-YDSDDMEMMLNCHTMEGSD--DMPGHVKSSLLGVSLNIPVSKGSLALG------------- Sporo1 RAKGCHLITNEIDHLKN--VGMLFLFLQHTSAGLSLNEN-CDPDDMDMALDEHVDEGPD--DSVSHTKSSIIGVNVQIPIGNGKLQLGGIYLTEFRVVATI Stehi1 RGKGCHLVTDEISGLRGVQVGMLFLFIQHTSAALTINEN-YDRDDMDMALDKHTDEGPD--DSVSHTKTSLIGTSISVPITDGRLNLGGIYLTEFRIVATI Tapde11 RSKGFYIITNEIP-ISQYKIGLCNIFLLHTSAAITINEN-WDADDLSDAMDRHNAEGPD--DMPSHIKSSLLGASLTVPIKDGKLALGDIQLAEFRLIVTI Thetr LPRGVHIITSVIPSLPEVEVGTVSIFLPHTSASLLLNEA-CDPSDLEMVLNTHDDEGPD--DMPAHAKSMLLGASVTLPVRSSRLLLA------------- Treme1 ----MHLITDVIQGLKDVSVGIFTLNCLHTSAGLTVNEN-CDPSGMDMGLDQHTDEGPD--DSVSHLKTSLIGNSITLPISAGKLHLGGIYLAEFRVVATI Trire2 KSRGSYLITDQIPEIQEYKVGLLNLFVQHTSCALSLNEN-WDEDDMSDALDRHDAEGPD--DMPAHIKSALIGASVTIPIKDGKLATGGIWYLEFRIIATI Umbra1 RPRGCHLVHDEIPEIRKYKVGMANVFLQHTSASLMLNEN-YDPTDYEMALNVHTDEGPD--DMPGHLKSGLVGVSLNIPITQGRLNTGGIWLCEHRVVVTL Ustma22 RSKGCHLITNEVEGLKGVKVGILTLFIQHTSAALTLNEN-FDRDDMDMALDKHTDEGPD--DSVSHTKTSLIGPSVTIPITDGRLNLGGITLCEFRIVATI Walse1 RSKGCHLVTEEVDGISNTQVGLLNLFIKHTSAALTINEN-FDYTDMDMALDEHVDEGPD--DSVSHTKTSLIGPSLTIPITNGNLALGGIYLTEFRICCTI Zygro1 ----------------------------------------------------------------------------------------------------- [Cluster2560.fasta_al_trimmed; alignment length = 80] Allma1 -------------------------------------------------------------------------------- Ashgo11 TNTMGLQLHEFVYLVERGT-VLLSVQDVYALFLDEFLVYAHLKRLGFIVVSQLYEELSQHV-WKPFKKKTPPDFQVVVYN Aspfu1 FKTMGLLPEEALYMLERGS-LPMSLQAAYACFIDRFTVYTGLKRLGYTLTRDIYRKL-SIV-YKPFRKSAPPDLRIAVID Aurde31 FTTIGLLPEEALYLIERGS-MPMSVQQAYAEMLDHYQVYAYLKRLGYNVLRRLFERL-RIV-YKPFRKSERPDYQVAVVN Batde5 FKSIGLLPEETLFLIDQGA-LRVTVQHAYSLLLVAYQVYAYLKRLGFYTFRSIKQLIFRLV-YKPFKKSDRPDFAVVGVQ Botbo1 FANIGLLPEEALYMIERGS-MPMSVQQGFAEMLERYQVYSYLKRLGYLCTRDIFKSL-RIV-WKPWKKTALPDFEVVVIN Botci1 FRTIGLLPEEALYLVERGN-LPMSLQAAYAMLLERYNVYANLKRNGYVVMRSIYRQM-AVI-WKPFAKTNPPDFRIAIVD Caeel LESMGVYPEEAVYLMETGS-ADLSLLEAFSILMSKYEAYKHVKRTGLVVLRTVLRRLKKLV-FSPFSHRLPPLFSLICYS Canalb1 FKDLGLNSLETIYLAERGS-LALDLEYLYSLLLANYQVYAYLKRLGYIIQEDVFKNL-KLV-WKPFSKKTPPDFQLCVVD Cangl LQTMGLDFHELVYLSERGT-VPLSIEDLYLLFYDNFLVYSQLKRLGFIVLLQLYNSIGSLL-WKPFKKKSPPDYQIVVYN Capow MISQGLMPEEAIYLLDRGR-IRLSVQEAIAVLMETLQLFIHLKRLGYVVRRDALKQA-ALV-YKPFRKSAPPDFRVVVCK Catan2 -------------------------------------------------------------------------------- Cioin MQTKSLFPEECLFLLDVGD-IELSMQDAYTLLLDEYQVYAYLCRVGYRVQRTEMKNLHKLV-FQTFRRTKPPFLRVIISA CocheC53 FQTIGLLPEEALFLLERGT-LPMSLQSAYAAFLEMYNVYAGLKRSGYVIFRDIYRLL-KLV-YRTFRKSARPDFRICVVD Coere1 -RTFGLQPEEWLLFFERGS-LRLDGLNVWTHAMDLYRGYAYLRRLGYVVCQNVFRGL---V-YKPYKKKSPPEYHMAVKH Conco1 -------------------------------------------------------------------------------- Conpu1 FSVMGLLPEETLYLIERGT-MPMSVQQAYSELLEKYQVFAYLRRLGYVVTRSILRSL-RIV-YKPFRKSAPPDFCMAVVN Copci FSSMGLLPEEAIYLIERGS-LPMSVQQAYAEMLEKFQVFAYLRRLGYVVTRHIFRSL-RFI-YKPFKKSNPPDFQMVVVN Croqu1 FSSIGLMPEELLYLIERGT-VPMSVEWAWGEILERYQVYGYLKRLGYIVLRSIFEAL-RVV-YKPFPKTAPPDFEVCVVN CryneH991 LDTMGLLPEEALYLLERGS-LEMSVMEGFGAFWERYQAYSYLKRLGYNVQRSLFSYL-RVI-WKPWSKRNWPDYFAAVIQ Crypa2 MLGTGLLPEEALFLIERGT-LPLSLQAAYALLLRNLQVFSNLNRAGFNVIRPIYKQL-ALI-WRPWSKTKPPDYHLAIVD Debha1 FKDMGLEPLEVVYLVERGS-MSLSLSHIYTLAMDSYIVYAYLKRHGYLIQTSIFQAL-KLV-WKPFSKKNPPDFHICVVN Dekbr2 LESMGFNYEEALYLVERGT-CPLTLEAVYSLLLDRYLVYSILKRNGYIVRRSYFNFFTYLV-WKPFKKKSPPDFQIVVVK Dicdi FDSVGLHIEEAIYFQDLGI-VPLSVQESFKLFIYKYTAYCYLKKLGYILIRSINRKL-QIV-YKPFKRTNPPDFFLSISK Dmel FENFGLEYYEAMFLLEVGR-LVVSIEQAYVLLYTNYLVYSALSRSGYIVVKEIFEKF-DLL-HLHFKKSAPPNFNVIILP Enthi -------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------- Fomme1 LNTLGLLPEEALYLIERGS-MPMSLQQAYAEMLERYQVYAYLKRLGYTVIRSVFSSL-RFV-YKPYRKTAPPDYSVIVVN Fusgr1 QKDIGLLPEEAIFLVERGT-MPLSLEAAYSLFLPQYQVYSNLKRAGFIVLRPIYDQL-ALV-WKSFSKKNPPNFRIAVVD Galma1 FSNMGLLPEEAIYLIERGS-LPMTVQQAFSEMLEKFQVYAYLKRLGYVVTRSLFRSL-RFL-YKPFRKSAPPNFQIVVVN Ganpr1 FNTVGLLPEECLFLLETGR-LTVSMQQAYGLMFSQYQVYSHLKRLGFAVFRLLSTSL-AIV-YRAFRKSAPPDFVVHVRT Gloin1 FHNMGLYPEECLFMMDRCS-LDMSLQQAYC--LEKYQVYAHLKRIGFTVLRQVYKKL-QIV-YKEFKKKNPPLFHVVVAS Hisca1 FRTVGLLPEEALYLLERGS-LPMSLQAAYACFLQRYIVYANLRRGGYAVIRDIYRAL-SIV-YKPFRKSTPPDFRLAVID Klula1 TNTVGLQFHEFVYLVERGS-VLLSLQDVYSFFLDEFFVYAYLKRMGYIVFPAIFESINKTV-WKPFKKSNRPDFQIVIHN Lacbi2 FSSMGLLPEEAIYLIERGS-MPMSVQQGYSEMLDRFQVFSYLKRLGYVVTRSLFRSL-RFL-YKPFKKTAPPDFQIVVIN Lenti61 LSTMGLLPEEALYLVERGA-MPMSVQQAYAEMFERYQVYAYLRRLGYVVTRSLFKSL-RFL-YKPFKKTASPDFSVVIVN Malgl1 CVHVGLFPEEAVYLIERGA-LPISVSQAYSHLLARYQA----------------RSL-K--------------------N Mellp23 FSSIGLMPEELLYLIERGT-VPMSVQWAWSEILERYQVYGYLKRLGYIVLRSIFRAL-RIV-YKPFPKTAPPDFEVCVVN Mnele -------------------------------------------------------------------------------- Monbr -----LYPEEALFLAERGA-FPLSLQEATALLYAEYLTYTHFRRNGYHVRRRVLEQV-RIV-FRPFRKTDPPAAAVVVCS Morel2 FVSMGLYPEEALYLVDRSS-LDLDVQQTWSLCMDRHLAYAYLKRLGYVVTRQVLQRI-RIV-YKPFKKRQPPDYRVVVVS Mucci2 LHSMGLFPEEAAFLVARNA-LPVGFEDYCQLMFDKYQVYAYLKRLGYIVVRHMYSTL-QIV-YKPWKKKDPPDFRVVVRS Mydma FRKQGFNAEETLFLVDQGV-LPLSFHAVFMLILEYYQTYAYLCRLGYIVRRKVIESL-KLV-FNS-KKKSEPLFRIIVCK Neucr2 SQSLGLLPEEALYLVERGS-LPLSLQAAYALLLQKFQVFSHLKRAGYNVIRTIYNYL-SLV-YKAFTRTRPPDFYISVIS Orpsp11 FETMGLFPEETLFLIEKGSLLPISIQQAYSIIFEKY-------RVG-----EVYSKI-SIV-YKPFSKKKKPDFYLIVQ- Pench1 FKTMGLLPEEALYLIERGS-LPMSLQAAYACFLERYSVYTGLKRLGYALVRDVYRKL-AII-YKPFKKSAPPDFRIAVVS Phybl2 VHTMGLYLEEAAWLISRNA-LPKLFEDFCLQMYEKYQVYVYLKRLGYIVQRDVYSTL-QIV-YRPWKKRDAPDFRV---- Picst3 FRDMGLNSLEAVYLVERGS-VAMDLEFLYSVALDQYQIYSYLKRLGYLVQDDIYKSL-RLV-WKPFSKKNPPDFQVAVAN Plicr1 FTAMGILPEEAIYLVERGA-MPMSVEQAFAEMLEKYQVFSYLKRLGYAVTRSLFTSL-RFL-YKPFRKTAPPDFSVVVVN Polpo YESMGLHIEEAMYLASIGA-MPLVLQECYKLFFSNYQVYSFLKKQGYHLLRSINRRL-RIV-YKPFKKTSPPDFRIIIKT Pucgr2 FSSIGLSPEELLYLVERGT-VPMSVQRAWAEILERYQVYAYLKRLGYIVLRSVFNAL-SLV-YKPFPKSSPPDFQICVID Punst1 FVSMGLLPEETIYLVERGA-LPMSVQQTFAEMLEKYQVYAYLKRLGYVVTRSLLKSL-RLL-YKPFRKTAPPDFSVVVID Rhior3 LHTVGLNPEEAAFLVSRNA-LVLTFEDLCEFIFDKYLVYAYLKRLGYIVMRTVYSTL-QIV-YKPWKKKDPPDYRIVVKN Rhoto1 FGNIGLLPEEALYMVERGA-VPMSVQQAWDEVPERYQVYAFLRRLGYVVVRQIFSRL-AII-YKPYKKSDPPDFKMVVIN Rozal11 -------------------------------------------------------------------------------- Sacce1 MQTMGLDFHEFVYLAERGT-ILLSMEDLYSLFMDQYFVFAHLKRLGFILKPQLYQGLNRLV-WKPFKKRDPPDFQVFVYN Salro PQTMGLYPEEALFLVDRGV-LPLSFQEAMALCLRAYIVYAHLKRLGYIVLRRVIKQE-RLV-YTAFKRGNVPKFVVVPIS Schco3 FANMGLLPEEAIYLVERGS-LPMTVQQAYTEMLEKFQVYAYLKRLGYVVTRHIYRSL-RFI-YKPFKKSSPPDYQVVVVN Schpo1 FKTMGLLPEETLYLVERGS-MPMSLQAVYSASLENYLVYAHLRRCGFSVIREVYHDL-QIA-YKPFKKSALPDFRICVVS Sorma -----LLPEEALYLVERGS-LPLSLQAAYALLLQKFQVFSNLKRAGYNVIRTIYNHL-SLI-YKAFVRTRPPDFYLSVID Sphar IGPMALTPEEAMYLAEKRE-LPLSLEQARILLSQIYKTYGYLKRLGFVVRQDASEVSSDILPLRPFKRSRAPDFVVRCIL Spipu1 FQVIGLLPEEALFMLERNA-LIVSVQHGYNLLMNVYQIYAYLKRLGYIVLRDIYKQL-QVV-YKPFRKSNPPNFRVVAQR Sporo1 FGSIGLLPEEALYMNERGA-IPMSVQQAWSELPERYQVYAFLKRLGYTLVRQLFSRL-QIM-YKPYKKSSPPDFRIVVVN Stehi1 FTSMGLLPEETLFLVEKGA-LPMSVQQAFAELLEKYQVFSYLKRLGYVVTRSIFKSL-RFL-YKPFKKSSPPDFSIVVVN Tapde11 FKSIGLLPEELLYMVERGN-VPMSLQAAYAELLDQFQVYAYLKRAGYMVLRDIYSRM-SFV-WKPFRKSAPPHFRVAVLD Thetr -------------------------------------------------------------------------------- Treme1 YDSLGLLPEESLYLLERGS-LEMSVMEGYGNFWERYQAYAYLKRLGYTVQRSLFSHL-RIV-WKPFSKVRWPDFFVAAVE Trire2 MKDIGLLPEEAIYLVERGT-VPLSLEAAYSLFLPKYQVYAHLKRAGFNILRPIYQQL-ALV-WKPFSKKNPPDFRIAVAD Umbra1 FQSIGLYLEEACFLMNVGQ-LSISFRDLYVAVFERYQTYAYLKRLGYHVIRSIFSAL-RIV-HKPWKKTNPPTYRVSVCR Ustma22 FETVGLLPEEALFLTERGS-LPMSVQQAFAALREAYLIYAHLKRLGYVVQRAVFSSL-QIA-WRPYRKSHPAEFRIVILN Walse1 FSSIGLLPEEALYMVERGS-LPFSAQRAFDCCLEKYTIYAQLKRLGYIVKRSIFKSL-RLV-WRPFKKSSPPDFRIVVVD Zygro1 LHTLGLEFHEFVYLAERGS-IPLTIEDLYMLFLDTFFVFEHLKRLGFIVMPQIYQSLNQLV-WKPFKKKSPPDFQVVIYN [Cluster2576.fasta_al_trimmed; alignment length = 97] Allma1 RASLFGGAIETT-LPLIDVSTLRQVPDNQEVYVDSVSVVIELLELAS-HLEQYAIVGAMT-AQKFVVQWVIRISTDLVITWNLPQVARQLTVDWGLF Ashgo11 QQPLYGGKISTV-IPFLDASALREVPDTQEVFVTNESVIVDLLERAD-HLEDVATCVALAPVLKWLCFGLLRLATDVAISVNCPSMVSEFKLDEGLF Aspfu1 Q-PFYGGAIQGI-IPWVDGSSLREVPDHQELFLTLSSFIVEVNQRVT-HLRDLCRAHAYKGVVQMVHYLLVRLESDLLIFFNVPRLVQTLEIDWALF Aurde31 R-ELFGGTITLN-LPLVDASTLREVPDTQEVYLCTASWIIEILQRVD-HFNALAVCVGWQEVAKYIVLAVYRLNIDLVLSLNLPDVAQSLNIDYGLF Batde5 ---MY------------NSSQFRDVPDHQEVFVAESNIMFDLLEPDE-HFEQLS-------------------HTRIVLERTIP------------- Botbo1 Y-PLFGGAISVN-LPLLDASDIRQVPDTEEVLLSDISYIFEILQRVE-HFDALAILYGEQMVSKFIMLALFRVGTDIVFSINSPDAVQSFRIDFGLF Botci1 STPLFGGALIVD-LPFADVSTIRQVPDHQEVYLGFTSIIFDITERVG-HLEDIVTLIATQTPPHDIVLNLIRLSTDILVTINVPKIWETFKIDWGLF Caeel ------------------------------------------------------------------------------------------------- Canalb1 --ELYGGAITISKLPFIDISQIRQVPDTQEVFIFDHSFIIDLLERVD-HLQDIV-----------TLICLIRLDTDVLLQYIIPKIALSFTVDWNLF Cangl -TQLYGGAITTV-LPFMDVSMLREVPDTQEVFVENESIIIDLLQMVE-HIEDVTTCILTESVHKWICLALKRMETDALISINVPNIVKEFKVDKSLF Capow R-QLYGGAMTIS-LPFADVSGMRQIPDHQEVFVNDQSFMVDLLQYQ--HFNEIALLCGQQAVAKYIYLLLVRLTTDIVVTFNDPLALRSLAIDYGLF Catan2 PTPLFGGAITAL-LPLIDVSNLRQVPDNQEVWVQSASLIIELLHLDP-HLSQVLVVAQVGHLHKFLMVWVLRVETDIVVTWNLPVVARSLKVDWGLF Cioin ------------------------------------------------------------------------------------------------- CocheC53 ATPLYGGAITVD-LPYSDASLIRQIPSHQEVYLGYTSIVLEILEYVD-HFADLVTLTFIQTPPSPIQLILVRLATDIMITINSPKVLDSFAIDWGLF Coere1 R-ELYGGAMSMN-VPMTDVSKFREVPDNQEVFATDASVIIEILERVD-HFQQVAVLVSQQAVAKFLLMALLRITADVLITMNVP------------- Conco1 LTKLFGGAIEAP-TPFLDISTVRQVPDNQEVFATNQSIIFELLEAND-HFNQIAYVQGTQIIQ--IYLLIFRLTTDLIITWQVPQLAKSLVIDWSLF Conpu1 R-ELFGGAIQCT-LPLVDVSKLRQVPDSQEVFVSDASFIIEVLEHAP-HFTDIAVLRGKQSAVKFIFMGLFRVNVDLLVTANVPIMIRSLRIDYGLF Copci R-PLFGGAIVAK-TELIDASDLRQIPDTQEVFLSSVSVIVEILQRVE-HFKSLALLEGEQIVRKFIFMGLFRVNTDIVVTFNVPVFVRSFEIDFGLF Croqu1 NYDLFGGTIKIN-LPLLDVSQIRQVPDSQEVFITELSIIIEVLQKIS-HFDSLALLEGIQTVSKFIWMALWTLGTDLVLTINLPQAATSLKIDWNLF CryneH991 Q-PLFGGAISLD-LPSIDASDLRQIPNNQEVFLSDTALVLEILEMVE-HFNSIAILSGTQRIHKFIGLALWRVKADVVLSVNVNKAVGSLKVDYGLF Crypa2 HTPLFGGAIESD-LPFADVSKLRQVPDNQEVFIGFTSIIFDITERVG-HLEELVTLIATQTPKPDIILTLVRLSTDILITINVPEIWKTFKVDWGLF Debha1 ---LYGGAVTTV-LPIVDVSDMREVPDNQEVFIKDVSIIFDLLEQVD-HIDDMLVLNTKIHTCYVL----IRLETDIVISMHV-VAGENFNINWELF Dekbr2 RTDLYGGAITAQ-IPLIDASKFRQIPDTQEVYVENDALIIDLMERAD-HLKEICIVTSGENVKKWLILAIVRIKTDLLISYNVPKVLDSLKINWALF Dicdi R-QLYGGAIEID-IPFIDVTSYRHIPDHQELFSSDQSVIIELNEFQD-HYEVLVLL-AQQKIAKFIYMALVRLKTDLLITFNEATMLKSFKIDYSLF Dmel ------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------- Fomme1 R-QLFDGAITAE-LPLVDASTVRQVPDTQEVFFSDVSYIIEILQRVE-HFDSLALLDGSQKVTKFILLAVYRVGVDIVLSANLPNAARSLKIDFGLF Fusgr1 STPLYGGAITCD-LPFADVSKLRQVPDNQEVWIGFTSIIFDITERVG-HLEDMVTLISTQTPHVSIILTLLRLKTDILITINVPKIWETFKIDWGLF Galma1 R-ELFGGAITAG-TILIDAANLRQVPDTQEVFMSNISIIVEILQRVE-HFDSLAVLKGIQFVPKFILMALFRVHIDLAVTFNIPTFVRTFRIDFGLF Ganpr1 H-ELFGGAITAI-IPFVDASQLRQIPDTQEVFVTDASIIVEILEVAE-HFWNIAVVRGQSLIAKYVLVAVIRLSADIIITYNDPELLESFSIDLSLF Gloin1 K-ELFGGSISMY-IPFEDISNVRNVPDNQEVFATDQSIIVEILEFVK-------------------------------------------------- Hisca1 ---------------------MREVPDNQEAFVTRTSILIEINERLN-HLHEICQVPAYLAKALICRLLLIRLSTDIIAYIVVPNVVESFEIDYGLF Klula1 RQELYGGAISTV-IPFLDASMLRQVPDTQEVFVFDESVIVDLMQRVE-HLAEISTCIVVETAYKWMCVALLRLDTDVIISVHVPDMISSFKVDPSLF Lacbi2 R-PLFGGAIVAE-TPLIDASDVRQVPDAQEVLLSSVSIIVEILQRVE-HFDSVATLKGAQRVPKFIFMALFRLEIDLVVTFNVPKFVTSFRIDYGLF Lenti61 K-ELFGGSITTT-LPLIDASNFRQVPDTQEVFISGVSIIVEVLQSVD-HFDALAVLYGTQTVQKFILLALYRVNIDLVMTMNVPIAAKSLRIDYGLF Malgl1 HYQLFGGAISIH-LDYMDASDLRQVPDNQEVLLSDVSVIVEVLQCVG-HFDSLALAQGLQIVRKFISIAMWRLNVDLVLSIND-QAASSLHIDWGLF Mellp23 QTDLFGGAIKVE-LPLIDISQVRQVPDSQEVFI-DLSIIIEVLQKLS-HFDSLALLEGIQSVSKFIWMALWTLGTDLVLTMNLPLAAKTLQIDWNLF Mnele ------------------------------------------------------------------------------------------------- Monbr R-ALLEGAMRIG-LPFEDVSAFRQVPDTQEVFVTDQSVIVEILEMVP-HFNSLAVSIGVQRVAKFVHVACFRFSTDIVVSWNQPPMIESFAVDWSIF Morel2 Q-ELYGGAITIN-LPFGTISHVRAVPDHQEVFVEDQSVIVEILELAA-HFQQLALLLGQQRVAKFIMMVVFRLQTDIVLTYNVPEVVGSFTVDWGLF Mucci2 Q-ELFGGAIVVP-VLFVDASQFRQIPDNQEVFVTQQSLIFELLEQVE-HFQQLAVLQGSQKIAKFIILVVVRLETDFVISVNAPTILKGLHVDWSLF Mydma K-LLFGGALSCF-IPSQDASMIRDIPDNQEVFLNEQSIMIDIVEYQA-YFEDLAALSGQQYATKFINLLLYRLSTDILVIMNSPQMACSLNIDSTIF Neucr2 TTPLFGGAIVCD-LPFADVSRLRQVPDHQEVYIGFTSIIVEITERVG-HLEELVTLIATQTPKPSLILTLVRLKTDILITINVPKIWETFEVDWGLF Orpsp11 R-ELFGGAMTAI-MPFKDASIIREVPDNQEVYVTDQSIIIELLEQAQ-HFKQLAIVLGKQIISKFIYLAVIRVETDILISYNCPELIKSFNVDWELF Pench1 Q-EFFGGAIRGV-VPWIDSSTLREVPDHQELWLTLSNLIIEINQRVP-HLHDLCTIKAYRGVVSFCHFLLVRLETDLLVFFNVPALIGRLQVDWGLF Phybl2 Q-LLFGGAIVAP-IKFVDASLFREVPSNQEVFVTQQSLIIELLEQAD-HFAQLAVLHGSQQVAKFIVMAVIRLKTDIVISINAPGLLNNFEVDWTLF Picst3 QLQLYSGAICTA-IPLVDVSHIRQIPDNQEVFLFDKSLIFDLLESVP-HIEELV-----QQEVNFTFIAFIRLETDVLITLNVPDIGYNYFVDWGLF Plicr1 R-GLFGGAIVAQ-MPLIDASEIRQVPDTQEVFLSSISIIAEILQRVE-HFDSLALLSGTQQVRKFILLGLYRVSIDLVITMNVPALVRSLRIDYGLF Polpo R-QLYGGAIEIS-IPFIDITAFRVIPDHQECFVTDQSIIIELLERQD-HFNVVALL-GKQMMSKFVYMAIVRLKTDLLITLNAPELLKTLHIDYSLF Pucgr2 EVPLFGGAITIE-LPIIDVSTFRQVPDTQEVFIKDLSMIVEVLELVN-HFDSLARCYGLQSVAKFIWLGLWRLGTDLVLSFNLPHAARSLKIDWSLF Punst1 R-DLFGGAITAV-IPLIDASDLRQVPDTQEVFLSDVSIIFEILERVQ-HFDSVATLIGNQLVAKFILLALYRVNIDFVVTCNVPQVVQSLLIDYGLF Rhior3 Q-SLFGGAIVIP-LGFLDASQFRQVPDNQEVFVTQQSLIVELLEQVDLSFENF-------------------------------------------- Rhoto1 R-QLYGGAITTT-IPFVDASDLRQVPDTQEVFLSDLSLITEVLELVK-HFSSLAVLSGLQTISKFILLALWRIDADVTLCVNWPEAIRAFEIDFGLF Rozal11 R-SLYGGAISLA-IPFIDVSTLREIPDHQEVFTTDMSVIIELNTMAE--FGSSALVEGEQRISKFIYLAVIRIETDILISMNNPQILKSFKIDWNLF Sacce1 EVELYGGAITTV-VPFIDASTLREVPDTQEVYVTNESIIVDLLETVD-HVEDLTTGLVMEVANKWIGVALIRLDTDVVISINVPEMVRKFHVDTSLF Salro R-PLFGGAMSMT-VPFMDISMVRQVPNNQEVFATDQSFIIEILELPP-HFDVIAVMWGLQQVGKHVHVACFRASADIVVSFNSPQAIDTLQIDWSLF Schco3 R-DLFGGAITAR-TPLIDASDLRQIPDTQEVFLSSASIIVEILQRVE-HFDSLAILSGVQSVAKFVLMALYRVGIDLVVTFNIPSLVTSLQIDFGLF Schpo1 MVQLFGGALCAD-FPFLDASVLRQIPDNQEVFLENLTVIIELLEKI--HFNSIASVQGCQRVLEKIFVNVITLQTDIVISVNAPRVTRSLVLDKTVF Sorma STPLFGGAIVCD-LPFADVSRLRQVPDNQEVYIGFTSIIVDITERVG-HLEELVTLIATQTPKSSLILTLVRLKTDILVTINVPKIWESFEVDWGLF Sphar ------------------------------------------------------------------------------------------------- Spipu1 R-ELYGGAIVTD-IPFLDASDFREVPSNQEVFVTDQSIIIELLELAS-HFQQLAVIVGEQVVSKFIYMAVLRITTDLVISYNHPNMLRRLRIDWGLF Sporo1 R-PLYGGAISCS-LPFLDASDLRQVPDTQEVFLSDLSLIVEILELVK-HFSSLAVLTGTQTVSKFLQFALWRINADVTLCVNYPNAVKSFEIDFGLF Stehi1 R-ELFGGAIAAL-LPLVDASQLRQVPDTQEVFLSDVSIIVEILERVE-HFDSLAVLYGTQLVQKFILLALYRVGVDVVMTMNIPTAVRSLQIDFGLF Tapde11 ------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------- Treme1 R-PLFGGAISIM-LPYIDASDLRQVPDNQEVFLSDTSIVIEVLSMVE-HFESIAILTGLQKVHKYIGVALWRCKADLVYSVNVNRSVGSLRIDWNLF Trire2 NIPLYGGAVTCD-LPFADVSKLRQVPDHQEVWIGFTSIIFDITERVG-HLEDMVTLIATQTPHAAITMTLLRLDTDILITINVPRIWETFEIDWGLF Umbra1 R-PLFGGALSAP-LRYLDASQIRQIPDNQEVFVTEQSLIIELLDLVP-HFQQLAVLKGLQKISKFIVMAIIRLHTDVAISVNVPQLVKGFKVDWSLF Ustma22 R-ELFGGAILVE-LPFIDASDFRQVPDNQEVFVSDISLIVEVLQLAN-HFSSLARLTGTQMIRKFIRVALWRLQIDLVLSVNESLAASSLQIDWNLF Walse1 KYECFDGAINFE-SDLIDASKFRQVPDNQEVFIE-VSVIVEVLEHVK-HFDSLA----CE-------------------SIDQPKIKIALAVDLKVL Zygro1 PVSLYGGALRTV-LPFIDASLLRPVPDTQEVYVLNESITVDLLERIE-HVTEIFACIAHDV----LCVGLIRLGTDVVITINVPTILNQFEVDGSLF [Cluster2589.fasta_al_trimmed; alignment length = 247] Allma1 HLLPPS--WKTSVAAWLAEDIPSFDYGGFVVGDKDDSATLWCKAGVLAGVPFVDEICRVEWIAKEGEFIVAKVYGQARNLLLGERTALNL-MARCSGIATRARRMAELKAGFKGVIAGTRKTTPGFRHVEKYGMLVGGVDQHRMDLSSMIMLKDNHVWSGSITKAVQKARQVGGFALKIEVECRSIAEAEEAITAGADIVMLDNFKPDSLKTAAVDLKARVLIEGSGGITEETVDVLSMGSLIDFSL Ashgo11 NLLPANGAWKHDITNWLQEDVPAFDYGGYVVGSATKTATLLCKQGVLAGVPFADEVLECQWLFVEGDELVAKVTGEARNILLAERTALNI-LSRCSGIASASRNIIASARGYRGTVAGTRKTTPGLRRLEKYAMLVGGCDTHRYDLSSMVMLKDNHIWAGSITRAVQDARAACGFTIKIEVECQSEAEADEAIAAGADVIMLDNFTGTSLRATAQRLKERFLLECSGGLRIDNLDIYSTSSIVDFSL Aspfu1 HLLPNN--YKRLITAWLEEDCPSFDYGGFVVGESEGEARLLGKSGVVAGVPFFDEVCTVEWHVKEGESICATVRGPIRQILLGERVALNI-LARCSGIATKSTTLVAALRGWQGTLAGTRKTTPGFRVVEKYGLLVGGADPHRHDLSSMTMLKDNHVWAAAIPRAVQAAKAAGGFSTKVEVECRSLEEANAAIDAGADVIMLDNFTPEGVRDAARQLKQDFLVEVSGGLTEANADILSTSSIVDFSL Aurde31 HLLPPS--WKTQVTAWLQEDAPSFDYGGFVVGEDEREAWLLGKGAVVAGVPFFTEVCSVEWHVEEGEVFVATVRGKARMILLGERVALNL-LARCSGIATKSKKFKDIATGFTGILAGTRKTTPGFRLVEKYGMLVGGIDTHRHDLSSMIMLKDNHVWSGSITQAVKKARSVGGFSLLVEVEVQSEAEADEAIEAGADIIMLDNFGPSQLADAAASLRKRFLLESSGGIDENNIDILSTSAVVDFSL Batde5 HLLPTN--WKLQVSSWLDEDTPTFDYGGFVVGETDQTAALYCKAGVLAGVPFFNQVCRVEWHVDEGTLIVARVYGKARHLLLGERPALNM-LARASGIATKASHLRKIKDNWHGVIAATRKTTPGFRIVEKYASLVGGVDTHRMDLSSMIMLKDNHIWAGSITDAVKKARSVGGFALKIEVECGSEAEATEAILAGADIIMLDNFNGDGIHVAAKNLKQMFLIEGSGGLTQDNVDILSFGAIIDFSL Botbo1 HLLPPS--WTSQVQAWLDEDTPSFDWGGYVVGEVQREAFLFGKGAVLAGVPFFDEVCEVEWHLKEGETFVATVRGKARHLLLGERVALNA-IARCSGIATISKRFKDIAEGYKGIIAGTRKTTPGFRLVEKYGMLVGGIDPHRHSLSSMIMLKDNHITSGSITAAIERARAVGGFTLTIDVEVDTEAAADEAIAAGADVVMLDNMDATQVSSVANKLRQKWLFEVSGGVEEGNLDIISTSAVIDFSL Botci1 DLLPVH--WKSQITAWFAEDTPSFDYGGFVVGDSERTATLYGKSGILAGVPFFDEVCSVKWHTKEGTLVVATVTGPVRKLLLGERVALNT-LSRCSGIATKSRDMEVLVRGYKGILAGTRKTTPGFRLVEKYGMIVGGVDGHRHDLSSMTMLKDNHIWAGSITDAVKAAKAAGGFALKIEVEVDSEEGADEAIEAGADIIMLDNFSGDGLKVAAKSLRQRFLLECSGGLTSENVDIISTSAIVDFSL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 NLLPVSGNWKQKITDYLTEDVPSFDFGGFVVGNTPETGSLYMKQGVICGIPFVNEVLQHKWIFSEGQFVVCTVKGSASNILLAERTALNL-LSRASGVATQSYKTKKLADGYTGIIAGTRKTTPGLRQLEKYAMLIGGVDTHRYDLSSMVMLKDNHITSGSITKAVKKAKSVCGFAVKVEVEVSNEKDAEEAIEAGADVIMLDNFKGEELRQVAQSLKKKFLLECSGGLTLQNLDIYSTSSIIDFSL Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow HLLPPS--WKTTVTQWLDEDIPSFDYGGFVVGEKEETAELLGKSGVLAGVPFFEEVCKVHWLVKEGDFVVATVTGKARNILLGERAALNM-LARASGIASRARELRKLKDGFKGVVAGTRKTTPGFRLVEKYAMLVGGVDTHRMDLSSMIMLKDNHVWSGSITNAVRRAKTVGGFALKIEVECRSIDEAREAITAGADIVMLDNFDPEALKVAARILKQEVLIEGSGGITSETLDVLSMGSLVDFSL Catan2 HLLPPS--WRQSITAWLQEDIPSFDYGGYVVGAKQDEATLWCKSGVLAGCPFVDEICKVHWLVTEGTHVVATVTGTARDLLMGERTALNL-MARCAGIATRARKLADLKAGFKGVIAGTRKTTPGFRLVEKYGMLVGGVDQHRMDLSSMIMLKDNHVWSGSITKAVHQAKRVGGFALKIEVECRSEVEAEEAIAAGADIVMLDNFEPKALGVAATSLKTRVLIEGSGGITEETVDVLSMGSLVDYSL Cioin YILPQA-KVASLIKSWLEEDCPSFDYAALAVGEKYNRAELLIKSGIVSGVPFFDAVCEVDWLVSEGMKIIALIRGEARSILIGERVALNC-MARCSGISTLAQSFIEKTREWNGRIAGTRKTTPGFRLAEKYALVVAGADTHRYNLSSMVMLKDNHISSGNVSSAVERVKFAAGFSVKVEVECQSLEEAIEAVESGAEIIMFDNFTSEELHIAAAALKEMVIIEASGGITEDNLDVISSSKLVDYSL CocheC53 HLLPQT--YKRLVSEWLEEDTPSFDYGGFVVGEEMSEAKLLGKSGIVAGVPFFDEVCTVEWHVKEGTSFCATVRGPVRHLLLGERVALNT-LARCSGIATKSHRLLTLLRGYPNILAGTRKTTPGFRLVEKYGMLVGGVDAHRVDLSAMTMLKDNHIVAGSITNAVKAAKAAGGFAIKVEVECQSFEEADEAIAAGADIVMLDNFTPEGVQVAAKDLKDKFLVEVSGGLTEHNVDIVSTSSIVDFSL Coere1 ALLPTT--FARTIEDWLAEDIPSFDYGGYVVGDDEKVATLYCKSGVLAGVPFFNEVCIVVWSFEEGAEIVAKVSGPARRILMGERLALNI-IARCSGIASRARRLQNLANNFTGVIAGTRKTTPGFRLIEKYGMEVGGADTHRMDLSTMVMLKDNHIWAGSITNAVAKAKEVSGFSVKIEVECQSEAEAMEAIGAGADIVMLDNFSAEELCAAAHSIKSQVLIEASGGITEDSADIISFGSMVDFSL Conco1 YLLPPQ--WNKQIELWLQEDIPSLDYGGFVVGIKEETSVLYCKSIVLAGVPFFNEVCSVEWLFEEGTVIVAYVRGKCKDILIGERLALNI-FGRCSSIATQSKRFSNLKEGFNGVIAGSRKTTPGFRLVEKYGMLVGGCDMHRMDLSSMIMLKDNHIWSGNITEAVKAARSVGGFSMKIDVEVGSFEEACEAIEAGGDIIMLDNIEPPTLHEVAKNLKEKFLLEASGGVTLDSIDIISMSGLVDFSL Conpu1 HLLPTS--WKSQVTAWLAEDTPSFDYGGYVVGEVEREAHLLGKGAVLAGRPFVTEICSVEWLLEEGAIFVATVRGPVRQLLLGERVALNL-LARCSGIATKSMRIKDIATGYRGIIAGTRKTTPGFRLVEKYGMIVGGIDPHRHDLSSMIMLKDNHIWSGSITAAINAARAVGGFSLLLDVEVRSEEEADEAIEAGADVVMLDNMEGDALAGAARRLKKKFLFESSGNITEANLDILSTSAVIDYSL Copci HLLPPS--WKTQISQWLEEDTPSFDYGGFVVGEVPRTAFLFGKGAVLAGSPFVTEVCTIEWHVEEGDVFVATVNGKARHLLIGERVALNL-LARCSGIATKSKRIKDLARGYKGIIAGTRKTTPGFRLVEKYGMLVGGIDPHRHDLSSMIMLKDNHIWSNSIKKAIELARSVGGFSLLLDVEVRTEAEADEAIEAGADVVMLDNMEGDELLQVARRLKERFLLESSGGITEENLDIFSTSAVVDYSL Croqu1 HLLPPS--WKAVVTSWLAEDTPSFDYGGFVVGETESEAILLGKAGIVAGVPFVDEVCTVSWKVKEGDEIVAMVHGKARCLLLGERVALNV-LARCSGIATRSRNLVKLARSFRGLVAGTRKTTPGFRLVEKYGMLIGGIDPHRYDLSSMVMLKDNHVWSGSIPKAVSAARSVCGFSLRIDVEVRNEAEAIEAIEAGADVVMLDNFEPAEVKSSARRLKDKFLIEVSGGLTEQNLDIYSTSSVIDFSL CryneH991 HLLPSS--WSTEVQRWFAEDTPSFDWAGFVVGEEEQEAILWGKSGVLAGVPFFDEVCTVEWLMPEGSAVVAIVRGKARQLLLGERVALNT-LARCSGIATVSRRFRDLARGWNGVVAGTRKTTPGFRLVEKYGMMVGGVDPHRHDLSSMVMLKDNHIWAGSITSAIQAVRRVAGFSLLVNVECQNFKEADEAVTAGANIVMLDNMVGEDLHSAARRLKEKFLIETSGGIVEGSLDILSTSAVVDFSL Crypa2 ALLPSH--WKTQITTWLAEDTPSFDYGGFVVGDVPRTATLYAKSGILAGIPFFNEVCTVE---------LATVTGPARGILLGERVALNI-LARCSGVASMSRGFLVNLRGFRGRLAGTRKTTPGFRLVEKYGMLVGGADGHRMDLSSMVMLKDNHVWSGSIADAVAAAKAVAGFSLKVEVEVQSEAEADEAIGAGADVVMLDNFTGDGVKVAARSLKERFLVEVSGGVTLDNADIISTSAIVDFSL Debha1 NLLPANGKWKQLITDYLQEDVPSFDFGAFVVGNKQETASLYMKQGLISGVPFTAEVLEVEWLHKEGEFIVAVVKGPANKILLAERTALNL-LARSSGIATQSRLTKNLADGYTGLIAGTRKTTPGLRQLEKYSMLIGGVDTHRYDLSSMVMLKDNHITSGSITKAVKSARSVCGFAVKVEVEVSTEEDAREAIDAGADVIMLDNFEGPELQKAAQSLKKFFLLECSGGLTLSNLDIYSTSSIVDFSL Dekbr2 DLLPESSGWKSQVTSWLQEDIPSFDYGGYVVGSGIQKADLLCKAGMLCGVPFVQEVVEAIWFYEEGSFIVAEVTGPVKNILQAERLALNI-LARSSGIATQSYKTIQAARGYRGIIGGTRKTTPGLRLLEKYSMMVGGVDPHRYDLSSMIMLKDNHIWAGSITKAIKRAKRVGGFALKIEVEVRDEVEAREAIEAGADIVMLDNFNPSALRKAARQLKADFLLECSGGLKPENIDIYSTSSVIDFSL Dicdi QLLPKF-KIEKIIKEWLEEDIPSFDYGGCVVGSDEKVAHLLGKQGVFSGSIFFQEICKVIWFIKDGESFLAHVIGPVRNILIGERLSLNI-LSRSCGITTQGYNVKKLVDPWKGKIAGTRKTTPGFRLVEKLALLTAGLDTHRMDLSSMIMLKDNHIW-GNITNTVKNARSVGGFSLKIEVECRNQNEAIEAIEAGADIVMLDNFNPQDLQTVSTYLKQHITLEASGGITSATIDIISMGNLIDISL Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 HLLPPS--WKSQVTAWLAEDAPSFDYGGFVVGDAEREAFLFGKGAVLAGVPFFTEICTVEWHMQEGEEFVATVRGRARLLLLGERVALNL-LARCSGIATKSKRILDIARGYTGIIAGTRKTTPGFRLVEKYGMRVGGVDTHRHDLSSMIMLKDNHIWSGSITAAIAQARSVGGFSLLLDVEVRDEKEADEAIDAGADVIMLDNIEGQEMVNVARRLKEKFLFETSGNITESNLDILSTSAVIDFSL Fusgr1 NLLPPS--WKTSVTAWLAEDTPSFDYAGFVVGDGPRVATLWGKSGVIAGRPFFDEVCTVEWHAEEGNDVVATVKGPVRGILLGERVALNT-LARCSGVATKSSRLVSIARGYTGVIAGTRKTTPGFRLVEKYGMLVGGADAHRMDLSAMIMLKDNHVWSGSITDAVKAAKSVGGFSMKVEVEVQSEAEADEAIEAGADVVMLDNFTGDGVKVASRSLKERFLLEVSGGLQEDNFDILSTSSIIDFSL Galma1 YLLPPS--WKQQVAGWLAEDTPSFDYGGYVVGEVLREAFLLGKGAVLAGSPFVTEICEVEWHVTEGNTFVATVRGKARFLLLGERIALNL-LARCSGIATKSKRIKDLARGFTGTIAGTRKTTPGFRLVEKYGMIVGGIDPHRHDLSSMIMLKDNHIWSGSITAAIQQAREVGGFSLLLDVEVGSEAEADEAIEAGADIIMLDNIEGAELVSVARALKEKFLFETSGNITEANLDILSTSVVIDFSL Ganpr1 HLLPPS--WKKQVSEWFHEDIPVFDYGGFVVGETEQVAILYGKTGVIAGMPFFEEVCTVEWLIEEGEYFCARVRGKARFLLMGERVALNM-IARASGIATRGYRLIQIKAGYKGLIAGTRKTTPGFRMVEKYAMLVGGVDTHRMDLSSMIMLKDNHIWSGSITSAVQMARQVGGFALKIEVECRTEDEADEAIAAGADIIMLDNFKPEEMKETAKRLKERFLIEGSGGINEETVDVLSLGSLIDFSL Gloin1 HLLSPS--YKQEISNWLKEDVPSFDYGGFVVGEAQEVAILYGKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 HLLPLT--YKHTIATWLEEDCPSFDYGGFVVGEALGEARLLGKSGVVAGVPFFDEVCTVEWNVKEGETICAIVRGPMRKILLGERVALNI-LARCSGIATKTSTLVKILRGWKGIIAGTRKNTPGFRLVEKYGVLVGGADPHRHDLSSMTMLKDNHVWAQAIPTAVAAARAAGGFSMKIEVECRNIEEANAAIDAGANIIMLDNFSAAEVGKAAKLLKDSFLIEVSGGLNESNADILSTSSIVDFSL Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 HLLPPS--WKVQVTAWLTEDTPSFDYGGYVVGEVEREAFLLGKGAVLAGSPFVTEICTVEWHVQEGDIFIATVNGKARFLLLGERIALNL-LARCSGIATQSKKIRDLAKGYKGIIAGTRKTTPGFRLVEKYGMLVGGIDPHRHDLSSMIMLKDNHIWSGSITAAIQQARSVGGFSLLLDVEVGSEAEADEAIEAGADIIMLDNMEGSELVNVASSLKAKFLFETSGNITEANLDILSTSAVIDFSL Lenti61 HLLPPS--WKTQITTWLQEDTPSFDYGGFVVGEVQREAFLLGKGAVLAGAPFFEEVCEVEWHLKEGATFVATVRGKARHLLLGERVALNL-LARCSGIATQSKKIKDLARGYKGIVAGTRKTTPGFRLVEKYGMLVGGIDPHRHDLSSMIMLKDNHIWSGSITKAVQQARKVGGFSLLLEVEVGSEEEADEAIDAGADIVMLDNMEGAELVGVASRLKEKFLFESSGNVTEANIDIISTSAVIDFSL Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 HLLPPS--WKSIITEWLREDTPSFDYGGFVVGETDSDAILLGKSGILAGVPFVDEVCSVIWNLKEGEEVVAKVHGKARLLLLGERVALNI-LARCSGIATRSRNLVKLARSYKGIIAGTRKTTPGFRLIEKYGMLIGGIDPHRYDLSSMVMLKDNHIWSGSIPNAIKSARSVCGFSLRIDVEVRNEEEAIEAIESGADVVMLDNFKPQEVKTSSRKLKEKFLIEVSGGITEENIDIYSTSSVIDFSL Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 HLLPPN--WKTKITEWLQEDIPSFDYGGYVVGEKETTAILYGKSGIVAGVPFFTEICRVEWHVKEGEVLCAHVYGPVRQILIGERTALNM-MARCSGIASQAHRLRILKEGFKGVIAGTRKTTPGFRLVEKYGMLVGGADTHRMDLSSMIMLKDNHVWSGSITAAVQKAKAVGGFSLKIEVECRSEEEADEAIAAGADIVMLDNYEGDALKIAAGNIKQRVLVECSGGVTEQNIDIISLGSMVDFSL Mucci2 HLLATN--YKQLIADYLAEDVPSFDYGGFVVGEDDQVAILYCKAGVVAGVPFFDEVCRVEWTCKEGDWLIARVYGCARNILLGERTALNI-ISRCSGIALRARMVSDLQKGFKGVIAATRKTTPGFRLVEKYGVLVGGLDTHRMDLSSMVMLKDNHIWSGSITKAVQNARSVCGFALKIEVECQSEQEADEAIAAGADIVMLDNFTGEGLKAAAKSIKERFLIESSGGITYETCDVLSMSTIVDFSL Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 HILPVS--WKSQITAWLAEDTPSFDVGGFVVGDAPRTATLWGKSGILAGVPFFNEVCTVEWHATEGCHVLATVTGPARGLLEGERVALNI-LARCSGVATQSRHLLVNLRGYKGIVAGTRKTTPGFRLVEKYGMLVGGADTHRMDLSTMTMLKDNHVWSGSITEAVKAAKAAGGFSLKIEVEVQSEEEADEAIAAGADIIMLDNFTGEGVRVAARSLKERFLLEVSGGLTADNADILSTSSIVDFSL Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 HLLPGN--YKRVITSWLEEDCPSLDYGGFVVGESEGEARLLGKSGIVAGVPFFDEVCTIEWHIKEGEAICATVRGPIRKILLGERVALNI-LARCSGIASKSASMVGALRGWQGTLAGTRKTTPGFRLVEKYGMLAGGADPHRHDLSSMTMLKDNHVWAAAIPRAVQAAKATGGFSTKVEVECRSVEEANAAIGAGADIIMLDNFTPEGVREAAAQLKREFLIEVSGGLTEENADILSTSSIVDFSL Phybl2 HLLSIN--YRALVTQYLEEDVPSFDYGGFVVGEDEQEALLYCKAGVLAGVPFFDEVCKVEWHNQEGEWIIARVTGKARNILLGERTALNI-ICRCSGIALRARKVHELQKGFTGVIAATRKTTPGFRLVEKYGVLVGGLDTHRMDLSSMVMLKDNHIWSGSITKAVKQARSVCGFALKIEVECQSEEEADEAIAAGADIVMLDNFSGAGLQSAAKSIKQRFLIESSGGITYETCDVLSMSTIVDFSL Picst3 NLLPVNGRWKQQITDYLTEDVPSFDFGAFVVGDKVETASLYMKQGLICGVPFAAEVLEVIWHYKEGQYIVATVKGPANKILLAERTALNL-LARASGIATQSYITKKLADGYTGLIAGTRKTTPGLRHLEKYSMLVGGVDTHRYDLSSMVMLKDNHITSGSITKAVKSARSVCGFAVKVEVEVSTEDDAREAIDAGADVIMLDNFSGAELQKVAHNLKSYYLLECSGGLTLHNLDIYSTSSIVDFSL Plicr1 HLLPPS--WKPQVTAWLAEDTPSFDYGGYVVGEAHREAFLFGKGAVLAGSPFFAEVCEVEWHLKEGEVFVATVRGKARHLLLGERVALNM-LARCSGIATKSKRIKDLARGYKGIIAGTRKTTPGFRLVEKYGMLVGGIDPHRHDLSSMIMLKDNHIWSGSITAAIQQARAVGGFSLLLDVEVGSEAEADEAIDAGADIIMLDNIEGEHLVSVAQTLRQKFLFETSGNITEANLDILSTSVVIDFSL Polpo HLFTKS-KLQQQIKDWLDEDIPSFDYGGAVVGDVEEVAFLLGKQGVFSGTPFFNEICRVKWNIKDGEEFLAEVRGAVRNILMGERLSLNI-LSRSCGITTRAFDLRAIVDKWHGKVAGTRKTTPGFRLVEKYAMLVGGCDCHRMDLSSMIMLKDNHVWSGNITAAVKKARSIGGFSLEVEVECRTEDEAVEAVEAGADVVMLDNMLPPMLAVVSKSLKTKIVIEASGGVIPETLDIISMGSLIDISL Pucgr2 HLLPPS--WKSVVTEWLREDTPSFDYGGFVVGESQQEAQLLGKSGILAGVPFFDEICRVEWKFKEGDLVVAIVTGKARCLLIGERVGLNL-LARCSGIATQSHQMLKLARSYKGLIAGTRKTTPGFRLVEKYGMLVGGIDPHRYDLSSMVMLKDNHIWSGSITAAIQAARSVCGFSLRIDVEVRDEKEAKEAIEAGADVIMLDNFTPENVKTSARSLKQSFLIEVSGGLTEQNIDIYSTSSVIDFSL Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 DLLATN--YKALVSQYLAEDVPSFDYGGYVVGEEEQEAVLYMKAGVLAGVPFFDEVCRVEWCHKEGEYIMARVYGSARKILLGERTALNI-ICRCSGIAFRARQVYELKKGFKGIIAATRKTTPGFRLVEKYGVLVGGLDTHRMDLSAMVMLKDNHIWSGSITKAVENARSVCGFALKIEVECQSEEEADEAIEAGADIIMLDNFTGEGLKVAAKNIKERFLIESSGGITYETCDLLSLDTLHEKNL Rhoto1 HLLPPS--WKTVITSWLAEDTPYFDYGGFVVGEGEEEATLWGKSGVLAGVPFVDEICTVEWHLTEGADVVATVRGPARCLLLGERVALNT-MARCSGIAWKSRKVLLKARGWNGIIAGTRKTTPGFRLVEKYGMLVGGVDPHRYDLSSMVMLKDNHVWSGSITEAVHAAKSTAGFALRIHVECQSLAEAREAIAAGADIIMLDNFTPQGIREAAAALKEDCLVEVSGGLTEENMDILSTSAIIDFSL Rozal11 HLLPIS--WKYQIHEWLKEDIPSFDIAGYVVGEKFERASLICKSGILAGKPFVNEICSVSWCVDEGTEIVASVDGPARNILLGERLALNI-LARCSGIASECFKLNQKKRAWNGVISGTRKTTPGFRLVEKYGMIVGGCDPHRMDLSSLVMLKDNHIWSGSIANSVKAVKEICKFALKIEVECRNFEEALEACESGADIVMLDHVKPGSIADV-KSLKEKVIVEVSGGINENNIDVVSTGAIVDFSL Sacce1 HLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQGMLCGVPFAQEVLQVEWLFKEGSFLVAKITGPAKNILLAERTALNI-LSRSSGIATASHKIISLARGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWAGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKFLLECSGGLNLDNLDIYSTSSIIDFSL Salro GLIPEG-RLDELVRAWLAEDVPSFDIGGAVVGTKQETATLLCKSGVLAGRPFFDAVCKVTWEREEGEMLVATVQGEARKILLGERVALNT-LARASGIATRSRKMISLKEGWKGVVAGTRKTTPGFRLVEKHAMLVGGADCHRMDLSSMVMLKDNHIWSGSIPAAVSKARDMAGFSVKIEVECGTEEEAREAIAAGADVVMLDNFSPDDLGCAAARIKDDIIVEGSGGITVESIDVLSTSWIVDFSL Schco3 HLLPPS--WKPQVTAWLAEDTPSFDYAGFVVGDVEREAFLFGKGAVLAGSPFFTEVCQVEWHVKEGDTFVATVRGRARHLLLGERVALNM-LARCSGIATKSKRVKDLATGFKGIIAGTRKTTPGFRLVEKYGMLVGGIDPHRHDLSSMIMLKDNHIWSGSITAAIKQARLVGGFSLLLDVEVRSEEEANEAIDAGADIVMLDNIEGDELVAVAQRLKEKFLIETSGGITEGNLDILSTSMVIDFSL Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma HILPVS--WKSQITAWLAEDTPSFDVGGFVVGDAPRTATLWGKSGILAGVPFFD---------------LATVSGPARGLLEGERVALNI-LARCSGVATQSRHLLVNLRGYKGIVAGTRKTTPGFRLVEKYGMLVGGADTHRMDLSTMTMLKDNHVWSGSITEAVKAAKAAGGFSLKIEVEVQSEEEADEAIAAGADIIMLDNFTGEGVKVAARSLKERFLLEVSGGLTADNADILSTSSIVDFSL Sphar SLLPKG--WQSKVTDWLKEDAPTFDFGGFVVGTKPEEASLYCKSGVLAGVPFFDEVCLVKWEYTEGDFLVAKVRGAARDLLMGERVALNM-LARASGIATAARKLSEIKREWKGQVAGTRKTTPGFRLVEKYAMLIGGCDTHRMDLSSMIMLKDNHIWSGSISQAVKKAKSVGGFAMKIEVECQSVDEAREALNAGADIAMLDNFQPPALTTAAATLKAERLIEASGGITEQSIDIISLGSMVDFSL Spipu1 HLLPTN--WKKTVSSWLDEDTPSFDYGGFVVGETDQVAILYGKAGVLAGVPFFDEVCRVEWFLKEGEFFVAKVHGHARNLLLGERPALNM-LARASGIATRARRLRELKDNWKGVIAGTRKTTPGFRIVEKYAMLVGGVDTHRVDLSSMIMLKDNHVWAGSITNAVRAARSTGGFALKIEVECRTEAEADEAIEAGADIIMLDNFDGNGLISTAKKLKDRFLIEGSGGLTEENVDVLSFGSLIDFSL Sporo1 HLLPPS--WKSVISSWLAEDTPSFDYGGFVVGEGLEEAFLWGKSGILAGVPFVNEICTVEWHLKEGEDVVATVKGPARCLLLGERVALNT-MARCSGIALKSRKVLVLARGWKGIIAGTRKTTPGFRIVEKYGMLVGGVDQHRYDLSSMVMLKDNHIWSGSITQAVHAARSVAGFSMKIHVECQSLAEAREAISAGADIIMLDNFTPQGIREAASVLKEDCLVEVSGGLTEENIDIYSTSSIVDYSL Stehi1 HLLPPS--WKAQVTAWLAEDTPSFDYGGFVVGEAHREAFLLGKGAVLAGSPFVTEICEVEWHVTEGSTFVATVRGKARHLLLGERVALNL-LARCSGIATKSKRISDIARGYKGIIAGTRKTTPGFRLVEKYGMIVGGIDPHRHDLSSMIMLKDNHIWSGSITAAIQQARSVGGFSLLLDVEVRSEAEADEAIGAGADVIMLDNIDGPELQDVARRLKKRFLLESSGNITESNLDILSTSAVIDFSL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr CFLPPR--LDALVDAWLDEDIPSTDYGGFVVGSRPAVAHLLVKSGVLAGVPFADAVCSAEWAYADGAMFVAVVTGPTHRVLQAERTVLNV-LARCSGIATAARAFADKAAGFGGTVAGTRKTTPGFRDVEKYGMLVGGVDTHRTDLSSMVMLKDNHIWAGSITAAVETCRSVAGFSVKIEVETSSYDDAAEAINAGADVIMLDNFEPTELKAVAARLKADFLLEASGGVRLDTVDIISTSSLVDFSL Treme1 HLLPPS--WKSDVERWFAEDTPSFDWAGFVVGEEEQEAILWGKSGVLAGVPFFNQICTVEWLLPEGSVIVALVRGKARHLLLGERVALNT-LSRCSGIATVSRRFRDLARGWKGVVAGTRKTTPGFRLVEKYGMMVGGVDPHRHDLSSMVMLKDNHIWAGSITNAITAVRRVAGFSLLVNVECQDEAEADEAISAGANIVMLDNITGDGLHTAAKNLKQKFLIETSGGIVEGSLDILSTSAVVDFSL Trire2 HLLPPS--WQSQVTSWLAEDTPSFDYAGFVVGDNPRTATLWAKSGIIAGRPFFDQVCAVEWHADECSPIVATVTGPARGILLGERVALNA-LARCSGVATQSHNLVTKLRGYRGVLAGTRKTTPGFRLVEKYGMLAGGADAHRMDLSAMVMLKDNHVWSGSITEAVAAAKSVAGFSVKIEVEVQSEAEADEAIAAGADVVMLDNFTGDGVKVAARSLKERFLLEVSGGLREDNVDIISTSSIVDFSL Umbra1 HLLPNG--YKAQIAQWLQEDTPSFDYGGYVVGESDQKAVLYCKAGVLAGVPFFDEVCKVEWTAQEGEYLIAHVYGKARHLLLGERIALNI-ISRCSGIALKAHKVAQLQKGFKGVIAATRKTTPGFRLVEKYGVLVGGLDTHRMDLSSMVMLKDNHIWAGSITKAVQAARSVAGFSLKIEVECQSEEEADEAIAAGADVIMLDNFTGDGLKAAAKSVKQRFLVESSGGITYETCDILSMSTIVDFSL Ustma22 NLLPPS--WKVKVSEWLAEDCPSFDWGGFVVGEDKKRATLFCKSGILAGVPFFDEVCRVSWNFREGEWLVATVEGPSRKILLGERVALNT-LARCSGIATASGLFLKKARGYNGIVAGTRKTTPGFRDVEKYGMLVGGVDMHRYDLSSMVMLKDNHIWSGSVTNAVHSARSVCGFSLRIDVEVQSYQEAVQAIEAGADVIMLDNMEGETLISNAKRLKHEFLLESSGGIDIDNVDIISTSSIVDFSL Walse1 HLLPPS--WRSQVQQWLSEDTPSFDWAGFVVGEEYRDAKLLGKRGVLAGKPFVDEICTIEWHVKEGESFIATVRGAVRYLLLGERVALNV-LSRCSGIASMSRWFLDTSRGFKGIIAGTRKTTPGFRLVEKYGMIVGGIDAHRNDLSSMVMLKDNHIWSGSITNAIQAVRSVAGFSLRLDVEVRDEKEANEAIDAGADVIMLDNLDGEELHLVSKRLKEKFLLETSGGIEAHNLDILSTSAVIDYSM Zygro1 NLLPSNGQWKQDITNWLQEDVPSFDYGGFVVGSDQKAATLFCKQGYLSGVPFANEVLQVEWYFQEGDQLVAKVTGKAKDVLLAERTALNI-LSRSSGIATSSRRLMEAAKGYRGTIAGTRKTTPGLRRLEKYSMLVGGCDPHRYDLSSMVMLKDNHIWSGSITNAVYAARRVCGFAVKIEVECQSEQEADEAIEAGADVIMLDNFEPEGLKICASSLKTKFLLECSGGLKLDNLDIYSTSSIVDFSL [Cluster2591.fasta_al_trimmed; alignment length = 75] Allma1 MGTFLHACEGDMVCKSIPYFNAPIFQQNKTQIGKVDEILGPMNEVYFTVKGMNATSFKVDDKVYIGEDKLLPLER Ashgo11 MGAFMHDCEGDIVCRSIPYFNAMIYLENKTEVGKVDEILGPLNEVFFTIKGVKASSFKDGDKFYISPEKLLPIER Aspfu1 MGTFMHACEGEMTYPSV---TDPLH---QTPIGKVDEVLGPINQVYFTIKGIVATSFKPGDKVYIGGDKLLPLEK Aurde31 MGTFMHAVEDEMLCASVPFFNAPIYLQNKSAIGKVDEILGPITEVFFSVKGMVASSFKKGDKVYIAGDKLLPLDR Batde5 MGSFMHPCEGEMVCARIPYFNAPIYLENKTQIGKVDEILGPMNEVFFTVKGVVATSFKPKDKVYIAADKLLPLDR Botbo1 MGTFIHAVEDEMLCSSVPYFNAPIYLQNKSPIGKVDEILGPINEVYFSIKGMVASSFKKGDKVYIGGDKLLPIER Botci1 MGSFLHASEGEIVCESIPYFNAPIYLENKTSIGKVDEILGPINQVYFTIKGIQATSFKTGDKFYIGGDKLLPLEK Caeel --------------------------------------------------------------------------- Canalb1 MGSFMQACEGDIVCRSIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKGVKAESFKEGDKFYIGPDKLLPLER Cangl MGEFMHPCEGDVVCRSVPYFNAPIYLENKTQVGKVDEILGPLNEVYFTIKGVQATSFKEGDKFYIAPDKLLPIER Capow --------------------------------------------------------------------------- Catan2 MGAFMHACEGDMVCKSIPYFNAPIYLENKTQIGKVDEILGPMNEVYFTVKGMQAASFKQNDKVFIGDDKLLPLER Cioin IGKVMHPCQEDLVCKCIPYFNAPIYLENKSKIGKVDEIFGQIRDFCFSIKNMLASSFSSDTKFFIDPAKLLPLQR CocheC53 MGKFVHDCENEMFCESIPYFNAPIYLENKTPIGKVDEIMGPLNQVYFTIKGIQAKSFKAGDKFYIGGDKLLPLDR Coere1 MGSYMHACEEQMVCKSVPYFNAPIFLENKTQIGKVDEILGPINEVYFTVKGVVATSFKSADRVFIAPDKLLPLER Conco1 LGTFMHPCEGDMVCKSIPYFNAPVYLENKSQIGKVDEILGPMNEVYFTVKGVVASSFKVDDKVFIGGDKLLPLEK Conpu1 MGAFMHAVEDEMLCSSVPYFNAPIYLQNKSVIGKVDEILGPINEVYFSVKGMVANSFKKGDKVYIAGDKLLPIDR Copci MGSFIHAVEGEMLCSSVPYFNAPIYLQNKSLIGKVDEILGPINEVYFSIKGVIASSFKKGDKVYIGGDKLLPIER Croqu1 MGTCIHAVEGELLCSSVPYFNAPIYLANKSSIGKVDEILGPINDFYFTIKGMIASSFNPGDKVFIGGDKILPIER CryneH991 IGSFQHDVESEMLCSLIPYFNAPIYLQNKTQIGKVDEILGPINEVYFTVKGMLASSFKKEDKVYISGEKLLPIER Crypa2 --------------------------------------------------------------------------- Debha1 MGAFMQSCEGDIVCRSIPYFNAPIYLENKTQVGKVDEILGPVNEVFFTIKGVQADSFKDGDKFYIGPDKLLPLER Dekbr2 MGVFFHECEGNIVCRSIPYFNAPIYLENKQEVGKVDEILGPINEVYFTVHGVQASSFKDGDKFYIAGDKLLPLER Dicdi IGVFSHVCEEQIVCKLVPKFNCKVLSSSKNTIGSVDEIFGPINKVFFSVKGVQATSFKENDKIFVDSNSVLPIKI Dmel LGNYVYSCQNDLVCKVVPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKNVYANSFKPNQKLFIDPGKLLPIAR Enthi YGKFLHAAETVMVFKAYPAFNAIVYNEKKAEVGKVGEVFGPLNDYYFSVVGVKPDSYNVDDQIYLYTDKLFSVDR Falba SGVFRHQCEGELVLKLIPYFNAPIFLNKDTQVGKVEEIFGPINDVFFTVKGFVASSFKVDDKLFIGSDKLLPLAR Fomme1 MGSFVHAVEDEMLCASVPYFNAPIYLQNKSEIGKVDEILGPINEVYFSIKGMVASSFKKGDKVYIGGDKLLPIER Fusgr1 MGKFMHACEGEMVCESVPHFNAQIFLENKTAVGKVDEVLGPINQVFFTIKGIQATSFKEGDKFYIGSEKLLPLDK Galma1 MGTFVHAVEDEMFCSSVPYFNAPIYLQNKSQIGKVDEILGPINEVYFSIKGMVASSFKAGDKVFIGGDKLLPIER Ganpr1 MGTFMHPCENQMVCKSIPYFNAPIYLENKTQIGKVDEILGPLNEVYFTVSGFPATSFKVNDKVYIGSDKLLPLER Gloin1 MGLFLHACEGDMVCKSIPYFNAPIYLENKNQIGKVDEILGPMNEVYFTVKGIVATSFKPNDKVYIGEDRLLPLER Hisca1 ---------SKWVLSCARWFASPSTPKFRTSMHKVDEVLGPINQVYFTIKGIVATSFKSGDKFYIGGDKLLPLEK Klula1 MGAFLHPCEGDIVCRSIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTVKGVKAESFSEGDKFYIAPDKLLPIER Lacbi2 IGTFIHAVEDEMLCSSVPYFNAPIYLQNKSVIGKVDEILGPVNEVYFSIKGMVASSFKKGDKVYIGGDKLLPIER Lenti61 MGSFIHAVEDEMFCSSVPYFNAPIYLQNKSVIGRVDEIMGPINEVYFTVKGMVASSFKKGDKVYIGGDKLLPLER Malgl1 FGKFVHAVEGEMFCSSVPYFNAPIFLENKSQIGKVDEILGPINEVYFTVKGVVATSFKADDIVYISDDRKLPIER Mellp23 --------------------------------------------------------------------------- Mnele IGKLMNSCEGDLVLRAVPYFNAPIYLENKQQIGKIDEIFGPINEYMMSVKNMTADSFKRKQPFYINPMKLLPMSR Monbr VGSYIQPCEGDLVCKLIPYFNAMIYLENKSEVGKVEDVFGTITDVHFTIKGIKADGFNSDSKFYIDPFKLLPMDK Morel2 IGQFMHACEGEMVCKSIPYFNAPIYLENKSQIGKVDEILGPMNELYFTIKGMVATSFKVNDKVFIAPDKLLPLER Mucci2 --------------------------------------------------------------------------- Mydma IGEFLHPCESDLVLKCVPYFNAPIYLENKQQIGKVDEIFGPITEFFFSVKGMNASSFKKLQKLFIDPNKLLPLSR Neucr2 LGTFEHAVEGEMFYKSIPHFNAQVFLENKTPIGKIDEVLGPLNQVYFTVKGIVATSFKPGDKVFVGSEKLLPLER Orpsp11 --------------------------------------------------------------------------- Pench1 LGSVMHSCEGEMVCESIPYFNAPIYLENKTQIGKVDEILGPINQVYFTVKGIVATSFKAGDKVYIGGDKLLPLEK Phybl2 --------------------------------------------------------------------------- Picst3 MGAFMQACEGDIVCRSIPYFNAPIYLENKTQIGKVDEILGPLNEVFFTIKGVKADSFKEGDKFFIGPDKLLPLER Plicr1 MGAFVHAVEDEMLCSSVPYFNAPIYLQNKSVIGKVDEILGPINEVFFSVKGMVASSFKKGDKVFIGGDKILPIER Polpo LGAFTHTCEETIVCKLVPKFNCRVFTSNKQKLGQVSEIFGPINQVFFNVKGVQASTFKTDDKVFCDPFSVLPLKN Pucgr2 MGSFVHAVEGEMLCTSVPYFNAPIYLANKTTIGKVDEILGPINEVYFTIKGMVATSFNSGDKVYIAGDKLLPIER Punst1 MGTFLHAVEDEMLCASVPYFNAPIYLQNKSQIGKVDEILGPINEVFFSVKGMVANSFKKGDKVYIGDDKLLPIER Rhior3 MGSFLHACEGEMVCKSIPYFNAPIFLENKSQIGKVDEILGPLNEVYFTVKGMIAKSFKPDDKVYIGTDKLLPLER Rhoto1 VGTFMHAVEGEMLCSSVPYFNAPIYLPSKAAIGKVDEILGPINEVYFTIKGIVATSFTAGDKVCISTDKLLPIER Rozal11 LGTFMHASENEMVCKSIPHFNAGIYLENKTKIGHINEILGPINEVYFTIKGIVATSFQQDAPVYIGTEKLLPLER Sacce1 MGAFLHPCEGDIVCRSIPYFNAPIYLENKTQVGKVDEILGPLNEVFFTIKGVQATSFKEGDKFYIAADKLLPIER Salro LGSVVQSCEDDLVCKLVPYFNAMVYLENKQEVGKVDDIFGPVADAFFTVKGMKAGSFKSEDKFFIDPYKLLPIER Schco3 MGSFLHAVEDEMLCSSVPYFNAPIYLQNKSVIGKVDEILGPINEVYFSVKGMVASSFKKGDKVYIGGDKLLPIDR Schpo1 LGLFMHDCEGEMVCQSIPYFNAPIYLENKSQIGKIDEVFGPMNQVYFTVKGIVSSSFKVGDKVYLSGDKLIPLDR Sorma LGTFEHAVEGEMFYKSIPHFNAQVFLENKTPIGKIDEVLGPLNQVYFTVKGIVATSFKPGDKVFVGSEKLLPLE- Sphar LGEMLRCCEGDLVCKSIPYFNAPVYLENKSQIGKVDEIFGAIKDVHFTVKGMVATSFKNGSKFFVGTDKLLPLQR Spipu1 --------------------------------------------------------------------------- Sporo1 --------------------------------------------------------------------------- Stehi1 MGTFMHAVEDEMLCSSVPYFNAPIYLQNKSVIGKVDEILGPINEVYFSVKGMVANSFKKGDKVYIGGDKLLPIDR Tapde11 LGSFMHACENEMVCESIPYFNAPIFLQNKTPVGKVDEILGPMNQVYFTIKGIVSTSFKAGDKFYIGGDKLLPIER Thetr LGEFVHPCEGDLVFKSIPYFNAMVYSDNNALVGKIDDVLGAINSVMFTVKGVQADSFKSGFKVYVDTQKLLPLSR Treme1 IGAFLHPVESEMLCTLIPYFNAPIYLANKTQIGKVDEILGPINEVYFTVKGMQAASFKKDDKVFIGGDKLLPIER Trire2 MGKFIHACEGEMVCESVPHFNAQIFLENKTAVGKVDEVLGPINQVFFTIKGIQAASFKEGDKFYIAPEKLLPLDK Umbra1 MGSFMHACEGEIVCKSIPYFNAPIFIENKTQIGKVDEILGPLNEVYFTVKGIQAGSYSAGDKFYIGTDKLLPIER Ustma22 MGSFMHAVEGEMLCQSVPYFNAPIYLENKSQIGKVDEILGPINEVFFTVKGMVATSFKADDKVYISGDKLLPIER Walse1 MGEFQHAVESDMLCSAVPYFNAPIYLQNKNQIGKVDEILGPINDVYFTIKGIVATSFSKGDKVYIGSDKLLPIER Zygro1 MGQFMHPCEGDIVCKSIPYFNAPMYLENKTQVGKVDEILGPLNEVYFTIKGVHATSFKDGDKFYIGSDKLLPIER [Cluster2594.fasta_al_trimmed; alignment length = 87] Allma1 ASTASVVAMQSAKYWYQH--KKGPRFEQTSAQPVPMPAIDLIAEQPVKKVHQRVVACNG--GGGPLGHPKVYINLDQPGCGLRFEQE Ashgo11 --------------------------------------------------------------------------------------- Aspfu1 STTMPRQAPNRATTWASQQPRTGPRFEQTELQPQPMAAIELIHKQPVRWTNKRIVSCDG--GGGPLGHPRIFINTDKPECGLPFAHE Aurde31 SSSSVSQAPNYTKPWSSQRARAGPRFEQTDLQPKPLSAMQLVAEDPIRLVHGRKAVCDG--GVGPLGHPKVYISLDKPQSGIRFQQA Batde5 QSRAYVQSSNRDTTWSSQKAKNAARFEQTDLQPNPPSAQAFIQAVPITWVEARRTSCDG--GGGALGHPKVFINLDKDQ-------- Botbo1 TTAAS-QSPNYATTWSSQNPRSGPRFEQTSLQPNPLSAMELINNVPVKMVEGRRAVCDG--GGGPLGHPKIWINLDRPG-GLRFEQA Botci1 AFSA--QAPNREGKWSSQNPRSGPRFEQTEMQPAPQSAISLIHQQPVRWTHDRIVACDG--GGGALGHPRIFINTDKPECGLPFANE Caeel STITTK----------NQITKTGQAWDQSKKSVNPNVAMHLIDQRPPEDCGDKVVFCDG--GHPALGHPKVYINLDKPGCGNRFYNS Canalb1 SSVTSRQAPNRNVTWSSQEERYPYRFVQKEEQPRPYAAIDLIAKEPIKYLSHEIAVCDGNRGSTLQGHPKVFINLDQPKCGLRYAKE Cangl --------------------------------------------------------------------------------------- Capow SSSAST---------------RDARF---EQQTNKQIANDLIAQAKIIEIPSRSVWCDG--GGGALGHPKVYINLDPPGCGLRFVKS Catan2 STAAVRSSADSDFNYYHK---TGPRFEQTAQQPNPTPAIDLIAQEPVRKVNTH---C------GPLGHPKVYINLDQEGCGVRFEQE Cioin ------QAPSKFSVVGSKDKQTGQFFEQDKKLVNPNWGINLVAEIPPIEVEGRIAVCDG---------------------------- CocheC53 VSTATTQAPNYKGIWSSQNPRSGPRFEQTADQPRPYAAIELIHQQPVRWTHDRVVSCDG--GGGPLGHPRIFINTDKPQCGLPFAHE Coere1 STNV--QAPNRSVTWSSQRPRKDPRFVQADGQPRPMAAIELISEEPIREVEGRLACCDG--GGGALGHPRVWINLDDGKCGLRFKMS Conco1 EVKI--QASNRVATWSSQQDRQNPRFEQVSTQPQPQAAIELIHEEPIRMVEGRIASCNG--GGGALGHPKVYINLDKKGCGLRFQQK Conpu1 SSSSSSQAPNYPTTWSNQKPRSGPRFEQTALQPNPLSAMELVANEPIRVVQGRKAVCDG--GGGPLGHPKIFINLDQPGCGLRFEQA Copci STKPESQAPNFPSTWSSQKPRSSPRFEQTDLQPQPLSAMELIAQEPIRLVQGRSAVCDG--GGGPLGHPKIYINL----VRRNLPQQ Croqu1 ------QAPNRVTTWSNQIARRGPRFEQTELQPFPLAAIDLVHQEPIRMVESRVASCDG--GGGALGHPKIFINLDKPG-------- CryneH991 ATPPTPQSPNVPTTWSSQNPKDNGRFEQTEYQPNRPSAMGMVAEYPVRLVQGRKAACDG--GGGALGHPKIFINLGPRFASSKHTTR Crypa2 TTTARQQAPNRKEIWSSQRPRTGPRFEQTDLQPQSYSAMELVHKQPVRWTHDRVVACDG--GGGPAGHPRIFINTDKPECGLPYANE Debha1 ST----QAPNRKTTWSSQEARHPARFVQRDVQPRPYAAIDLIAKEPVRYLSHEIAVCDGNKGDNLQGHPKIFINLDQPKCGLRYAKE Dekbr2 ------QAPNRDSTWSSQISRNNVRFVGRSKQPFAEAAIELTKMQPIHYVSSDIAVCQGT--TSLLGHPKVYINLDKDMCGAKYARE Dicdi SQSLKSPPSNA------------------NVRPVE-PAEEMINKVRPVEIEGSSVGCDG--GNGPLGHPMVYINLDGKECGLRFVQK Dmel ----------------HSSCRTGQVFDKEKRYVNENWGIKLIEEVPPKECTERVVFCDG--GDGPLGHPKVYINLDKPGCGLRFVKK Enthi --------------------------------------------------------------------------------------- Falba ATNAVA-----TDTWSNQASRTGPRFLDVSLQPMPKPAIDLIAEQPVIEVAGRVASCDG--GHPALGHPTVYINLDDPSCGLRFRQA Fomme1 --------------------------------------------------------------------------------------- Fusgr1 TTSARQQAPNRVGVWSSQKPRTGPRFEQTDLQPQPKAAIEMIHKQPVTWTHDRIVACNG--GGGPEGHPRVFINTDKPECGLPFAHE Galma1 S----TQAPNHLTTWSSQRPRSSPIFEQTELQPNPLSAMALIAEEPIRLVHGRKATCDG--GGGPLGHPKIYINLDQPGCGLRFEQD Ganpr1 STTPVSQSPNNDGTWSSQRPRRGARFEQTALQPTPLSAQAMIAEEPVRTVQGHKAVCDG--GGGALGHPKVYIPLDKPGCGLRFIAE Gloin1 NTSV--DVPNYRNTWSSQRSRKGPRFEQTEAQPRPLAAIDLIAEEPIRYVEGRVAVCHG--GKGALGHPQIYINLDHPGCGIRFEQK Hisca1 TTTAPRQAPNRTTIWASQQPRTGPRFEQTEYQPRPYAAIELIHKQPVRWTKEKVVSCDG--GGGPLGHPRIFINTDKPQCGLPFANE Klula1 --------------------------------------------------------------------------------------- Lacbi2 SGTAQSQAPNYPSTWTSQRPREGPRFEQTELQPNPLSAMALIAEEPVRLVHGRKAVCDG--GGGPLGHPKIYINLDQPGAGIRFEQD Lenti61 STSTPVQAPNFPNTWSSQRPRSGPRFEQTELQPTPLSAMEMISKEPIRVVHGRKAVCDG--GGGPLGHPKIFINLDKPGCGLRYEQA Malgl1 PTATMSQAPNRYETWSSQRPKRGPRFEQMSSQPQSLSAMELINNYPLQFTQERVTSCDG--GDGPLGHPRVFINLDKPECGIRYQKI Mellp23 TSTVLSQSPNRVTTWSNQGVRKGPRFEQTDLQPFPLAAIDLIHQQPISMVSGRVASCDG--GGGALGHPRIFINLDKPGCGLRFEQE Mnele --------------------------------------------------------------------------------------- Monbr -STLLR----------CGQVRYEQRFIND----NPNWAIDLIHEEPITIVDGKTAVS----GGGPTGHPVEFLNLDQDKSGEFFVRR Morel2 ANNI--QSANRATTWSNQIEKKGPRFENTEAQPQPKAAIELIAEEPIRMVEGRRARCDG--GGGALGHPAVWINLDRPGCGIRFEQK Mucci2 TTSI--QAENRATTWSSQRAKVGPRFEQMSTQPNPMAAIDLIAEEPIRFVKERITHCDG--GGGALGHPKVYINLDKPGCGIRFQKP Mydma ------------------------KYDEDNDN----IAAKLIDEIPPKEVSQRVISCDG--GGGALGHPKVFINLDKPGCGLRFKKK Neucr2 TTSGHQQAPNRAEVWSSQKPRTGPRFEQTDLQPQPWAAIELIHKQPVKWVHERIVACDG--GGGPAGHPKIYINTDKPECGLPFANE Orpsp11 --------------------------------------------------------------------------------------- Pench1 SSTVPRQAPNRATTWASQQPRVGPRFEQTETQPRPYAAIELIHRQPVRWTKSKVVSCDG--GGGPLGHPKVFINTDKPECGLPFAHE Phybl2 TTSL--QAPNFVGTWSSQRPKSGPRFEQIATQPNAMAAIELIAEEPIQFVSERVTSCNG--GGGPLGHPKVYINLDKPGCGIRFEMN Picst3 ------QAPNRNVTWSTQESRYPHRFVQREAQPRPYAAIDLIAKEPVRYLTHDVAVCDGNRGSTLQGHPKVFINLDQPKCGLRYAKD Plicr1 SSTPTTQSPNYATTWSHQRSRENPRFEQTELQPNPLSAMEMINNEPIRLVAGRKAVCDG--GGGALGHPKIFINVDQPGCGIRFEKD Polpo AVVLRSIVPDK------------------DVMPRQ-TAEHLIHQVKPVEISADKIGCDG--GNGPLGHPMVYINLDNAECGIRFVKK Pucgr2 QPNVSSVPPAKAVTWSNQRPKTGPRFEQTDAQPNPLPAIELIKKEPIRMVSSRVAACDG--GGGALGHPKIFINLDKPGCGLRFERS Punst1 --------------------------------------------------------------------------------------- Rhior3 TTSL--QASNRQTTWSNQRAKKGPRFEQTNTQPNPMAAIELIAEEPIRFVNKRIANCDG--GGGPLGHPKVYINLDKPGCGIRFQKV Rhoto1 HNQV--QAPNREATWSSQATRVGPRFEQTAYQPRPLAAIELIQEEPIRMVHARRAVCDG--GGGALGHPRIFINLDKPGCGIRYEQI Rozal11 --------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------- Salro VTTVAR--------------RQALRFAVA----TPPAAKDLILEQPITVVDGRVVAS----GGGSTGHPINFLNLDQNKSGDFFIRK Schco3 STTAPPQAPNYVATWSSQAPRSSPRFEQIETQPAPLSAMQLIAEEPIRLVQGRKAVCDG--GSGPLGHPKIFINLDQPGCGIRFQQD Schpo1 --------------------------------------------------------------------------------------- Sorma TTSGRQQAPNRAEIWSSQKPRTGPRFEQTDLQPQPWSAMELIHKQPVKWVHERIVACDG--GGGPAGHPKIYINTDKPECGLPFANE Sphar -----------------------------NAN----PAQDLVNQIPPVEVMGRIVSCDG--GGGALGHPKIFINLDNPECGIRYVQK Spipu1 TASSVSQAANRADVWSHQQKKTGPRFEQTSLQPNPLSAQELIDKVPVTFVEARRVACNG--GGGALGHPQVWLNLDKDECGLRFQQK Sporo1 ------QAPNRTTVWSSQAERRGPRFEQTMFQPRPLAAVELIKEEPIRLIHGRVAACDG--GGGPLGHPRVFINLDKEGCGIRYEQE Stehi1 SSSSSSQAPNYPSTWSHQRQRSGPRFEQTELQPAPLSALEMIANEPVRVVQGRKAVCDG--GVGPLGHPKIFINLDKPGCGIRFEQD Tapde11 --------------------------------------------------------------------------------------- Thetr ---------------------NGHKVDPA--QPKPSNAAELISKVPPVEIDGPATVCDG--GRGPLGHPRVFINLEPHRCGVRYVQS Treme1 ------QSPNVPTTWSNQNPKNNARFEQTDLQPNPPSAMGMVAQDPVRLVEGRRAVCDG--GVGPLGHPKIYINLDKPGCGIRFEQA Trire2 TTSARRQAPNRAAIWSSQKPRTGPRFEQTSLQPQPYAAIELVHQVPVKWTHDKIVSCDG--GGGPAGHPRIFINTDKPECGNPFANE Umbra1 TTAVT-QASNRAATWASQQPKVGPKFEQRSKQPNPMAAIELIGEEPIHYVTERIAVCNG--GGGALGHPKIYINLDKAGCGIRFERE Ustma22 SSNASSQAPNFPTTWSSQNPRKGPRFEQLRFQPQPLAAIEMIQREPIRLSSKRIAACDG--GGGPLGHPKVFINLDKPGCGIRFELD Walse1 STSVVPQAEDRATKWSRQRSKVGARFEQKGLQPNPKAAIELIAQEPVRLVEGRVASCDG--GGGPLGHPKIYIKLDKPGCGIRFEQA Zygro1 --------------------------------------------------------------------------------------- [Cluster2597.fasta_al_trimmed; alignment length = 113] Allma1 MTWREYFAARQRRRLRNHLFTFVGAPTGMYFATGL-EAPMAYGMVAFALGATAAMIT-PATLEGLWRVMDVLDK-EFYKRILKYRADAMYDYYGEKVTSFEAYRVWLRKQRKI Ashgo11 LSWPDFFALRKTERRINTGSSVLTAFLTAYISTGF-DPMVVLVGALFASSGLGYLCG-PLMGSAFFRVYNHKNR-VFLEHIKKNRVDALPDYYGEKIGSLQEYRQWLRDCQSH Aspfu1 LDWNSFFKLRASRRRYTLASSIIASMASQILSEGL-DPFVVLGLATATCGAVGWLAG-PFLGNAIWRLFLMREK-EFFDRIKRFRVDPVPDYYGEKIGSVQGYRQWLKDQRAY Aurde31 LSWPEFMSIRKARRRWELATTIPTTVACMYFFSGI-DPLFVYAIGGVGCTGLGYLIG-PSIGSAGWRLIDAKER-ELHRRIVKYRVPPLPDFYGEKIGSMRDYRHWLRDQSKY Batde5 ISWTEFFAMRKNKKLVERTVGGLGGVFGYYFLFGL-DPSMPYMLGAFSTGIVSAVAG-SLGANQLWRLFDLKEK-EFHQRILRHRPKEPPDYYGEHIYSFSGYRKWIRRQRKF Botbo1 --WPEYLAIRRGKRRWDLAAAIPMTALGQYFGHGV-DPIYVYGLATMGCGGLGYLLG-PVVGGSLWRMIEARDR-EFHQHIVKNRVDPVPDYYGEKIGSLHQYRQWLRDQAKY Botci1 LDWNTFFKLRRTRRWFQLGSSIGTGFGGQILTHPL-DPFITLGLVTFACGGAGWLTG-PILGTAAFNVMDIKEK-EFYARVKKYRVDPVPDYYGEKISSVAGYRQWLKDQRAF Caeel ----------------------------------------------------------------------------------------------------------------- Canalb1 LTWVDYFQLKKQNNRINTIAGVFTGLGGSYLGNGF-DPLMVMGGAVILGGLVGFLVG-PFIGSSIFRLFELKNT-EFLSRLRIKRPDPIPDYYGEKIYSLKDYKQWLRDCNAF Cangl LTWTDFFQLRKQERRINVGSSVFTALVGAYLSTGF-DPLVVVTAGLMASGALGYLMG-PAVGSQVFKLYNLKNK-EFLKHVIQNRVDAVPDYYGEKIGSVKEYRQWLRDCHAY Capow MPFNEYCKAKTVHNMASNIAGVPVAIGSWVFVMGL-DLMVIAGMTGMASAVLGFAGG-KWLYSQAYALMDARHA-DFVDRITTRR---SDDYYGDKIKSLSDYRKWLRVQHKR Catan2 VTWTEYLSLRKDMRLRNQIFSFVMSPMAFYVAAGI-ESPWIVGIGAMTVGAIAATMT-PVSLEALWRVLDALDR-EFYRRIQKHRAHALFDYYGATVVSRETYRKWLRKQRKT Cioin ----------------------------------------------------------------------------------------------------------------- CocheC53 LTWDAFFALRRTRRRIGQACSGIGAVGVTTMINGF-DPFMLMGLSTLGMMGVGWLIG-PIFGNQVFNLFTRKDS-AFFNRIKRHRVDPPPDYYGEKIGSVAGYRRWLKDQRAF Coere1 LNWDEFFRLRKQRRLWERLASLPCAMLGAVFASGL-DPLLLFGGSTLFCGLLGFVIG-PSVGRAWYRILDRKEI-EFFKHVKANRSDPLPDFYGEKINSLQAYRKWLRKQRNH Conco1 MSWQDYFKLKKKRRIIERVLSVPTTVAATYLLNGL-DPQIFLILAVAGSGMIGYFMG-PLLENVVFRAIKQKDS-DFFKRIAKYRSNVAPDFYGEKIFSVKDYRTWLRRQYEH Conpu1 LTWPEYLDIRKNKRRWETAATIPCTILGAYFGTGV-DPLFFYGGCTVACMGLGYLVG-PALGAAGWRMIEQKDR-DFHKRIVKNRVDPVPDFYGEKIGSLNGYRQWLRDQARF Copci LTWPEYLAIRRGRRRWETAATIPAGLLGAYFGSGI-DPFMAYGILTVACLGAGVLVG-PSIGGALWRFIDAKER-EFLRRIAKNRVDAVPDYYGERVGSLHQYRQWLRDQNKY Croqu1 MSWSQYLALRKQQRQYSLFTTIPSTTIGSHFATGL-EANYVYAIATFGCAVLGYLVG-PVIGHGLFRLMQERNS-QFYQHVQRNRVDPIPDFYCEKVGSLRDYRNWLRDQATY CryneH991 LSWPSYLSLRRQRRLWSTLTSVPTTFLGGYFASGV-EPMFVYGGATLGCMALGYLIG-PSVGATLFSLLEVMDR-EFYHRIKKNRADPVPDFYGEKIVSLSTYRRWLRDQAVY Crypa2 LDWNTFFQLRKTRRRWQVAFSVVMSLASILLSTPL-DPILTLGLMTIGFVALGWLAG-PSLGSTVFYLMTVKES-QFFARIKRNRVDPVPDFYGEKISSVAGYRQWLKDQRAY Debha1 LNWVEYLNLKKQNNRLNVASSAFTSLAGTYLGNGL-DPFMVMGGAVILGGGVGYLFG-PFIGTALFSLFKIKDQ-IFLQKIKHHRVDPVPDYYGERIYSLNNYKQWLRDCNAF Dekbr2 --WEEFLTLRKKQRRISIVSSVIGTLIAVWVASGL-DAFTVYIGGIMCVGVIGYLLGPPLIGDTVFNLYRIKQK-MFLKHVRKMRVDAVPDYYGEKIGSSNDYRQWLRDCNEY Dicdi ----------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------- Fomme1 LSWQEYLEIRGRKRRWEIAATLPSIFLGAYFGGGF-DPLYVYGFATLSCGGIGYLFG-PIIGSTVWRLIEARDR-QFHQHIVKNRVDPVPDFYGEKIGSLRQYRQWLRDQARY Fusgr1 LDWNSFFKLRVKRRRYQMLFSITNGIFAIFLSTPL-DPFMTLGLMTLAFSGLGWLSG-PSVGNQVFYIMTQKEA-IFFERIKRNRVDPVPDFYGEKISSVAGYRSWLKDQKAF Galma1 LTWPEYLAIRRNKRTWQTVATIPCALLGTYFGNGI-DPFFFYGFCTLGCVGVGALVG-PTIGTSIWRYIDNKDV-EFFSRVAKNRVDAVPDYYGEKIGSLHQYRQWLRDQAKY Ganpr1 FNWTTYFQMRRQRHRAEQVAGVVGGVAAYYVVVGILGPEVVGSLGIIFAAVVGRWAG-VLAGGEVWAAFVRRDK-SFGRRINEQRAPQHPDYYAEQVDSVQTYHRWLRQQRDY Gloin1 LTWNEYFVLRRKRRITERLVTIPTALGGAYFASGH-DPLVIYGFGTILCGFTGLMIG-PVIGSSIWKLMEQSDR-DFYAHIKKNRADPAPDYYGEKIKSVTDYRRWLRKQRDI Hisca1 LDWNSFFRLRASRRKYSLVSSIIASVFSQVFVAGL-DPFIVLGLATASCAALGWLLG-PVLGNSLWGLVALKEK-EFYSRIKRFRVDPVPDYYGEKIGSIQGYRQWLKDQRAF Klula1 MTWPEFFKLRKKERVFNTASSVATAIVFFYFSTGF-DPLMAITAGMITCAAVGWLLG-PIVGTALFKAFQEKQL-SFLAKIQKNRVNPVPDYYGEKINSIPQYRQWLRDCHSY Lacbi2 LTWPEYLAIKRNKRKWQMAVTFPSAMLGAYFGTGI-DPFFFYGICTLGCVGVGAILG-PTVGTALWRFIDSKDH-QFFQRIAKNRVDAVPDYYGEKIGSLHQYRQWLRDQGKY Lenti61 LPWQEYLAIRKRKRRWETAVTIPTTIGGSYFGNNI-DPMFVYGAATLGCAGLGYLVG-PIIGSSIWRTIEKRDK-EFHQHIVKNRVDPVPDYYGEKIGSLHDYRQWLRDQAKF Malgl1 ------------------------MILASYFMTGI-DPMFVYLGATLTCTGLGWLIG-PSFGSTAWSLMAQRDK-QFFDHIRKMRADPLPDYYGEKIGSLREYRHWLRKQCSM Mellp23 MSWSQYLALRKKQRQYALFATIPSTTIGLRFATGI-EANYVYAISTLGCAIFGYLIG-PTIGHSIFRLMQERNA-QFYAHIKANRVDPLPDWHGERVGSLSDYRRWLRDQAAY Mnele LQFNDFIKLKGRLKRMRYGAII----GGFTFASGV-DPMFVGTVMTFISGVTCALV--CVLGYRDITLYYEREQ-DFQRRLNFYR---SDDYYGDKIKDLTDYRYWIRVQQIK Monbr ----------------------------------------------------------------------------------------------------------------- Morel2 MDWNTYFALRKTRRNYERAFMVPSALVSYYFAQGM-DQVIVYGIGTVAAGLVGLAMG-PVIGNSVFRAVDRMDT-EFLKHIARNRADPIPDYYGEKIKSVSEYRAWLRKQREF Mucci2 PTWNDYFKLRKKRRVYEVASYLPSTVAPAYFLQGM-DPLMAAVASTLAAGFGGFLMG-PVVGNAFFKLMDIRDK-EFYEHIKKNRADAVPDYYGEKIQSVQDYRAWLRKQREH Mydma LSFDEYQSLKRSLRTKQRLSGIPFAFTGMATAYGL-DPIVFCGICGVSSSFLGYVLG-TNFYKLIWTLLQEKDK-DFLKRLEKHRFSQEDDYYGESIKTLSDYRQWVRTQ--- Neucr2 LDWNTFFKLRKTRRRVQLAFSVIMTLITAVLSTPL-EPMFAVGLMTASFGALGWLMG-PAMGGMVFNAMEIKEG-QFFARIKKHRVDPVPDFYGEKISSVAGYRQWLKDQRAF Orpsp11 ----------------------------------------------------------------------------------------------------------------- Pench1 LDWDSFFKLRASRRRYSLASSIVSSAVSQVLSGGL-DPFVVLGLATAACGAVGWLLG-PALGNGVWGLVNTKEK-EFFDRIRRFRVDPVPDYYGEKIGSVAGYRSWLKDQRAY Phybl2 PTWDDYFKLRKKRRMFELAAYPPSTILPAYCMNGL-DPVTGLGLLTLSTGFFGLLLG-PLFGDALFKLMEARDK-AFYERIKNNRADAVPDYYGEKIQSVADYRAWLRKQREH Picst3 LSWAEYFKLKKQNNIINTGASVFTGLAGTYLGNGL-DPLMVLGGAVFLGAGFGYLLG-PFAGTSVFKLYMARDK-EFLSRIRAKRVDPVPDYYGEKIYSLQGYKQWLRDCNAF Plicr1 LPWPDYLAIRRGKRKWETAVTIPLTIGGMYFGSGI-DPMFFVGGCVVSCAGLGYLLG-PVIGSACWRMIEARDR-EFHQRIVKNRVDPVPDYYGEKIGSLHQYRQWLRDQARY Polpo ----------------------------------------------------------------------------------------------------------------- Pucgr2 LTWPEYLALRKQQRRYALFATIPITTLGNYFATGI-EAPYVYGLATLSCGLLGYLIG-PSIGHAFFRLMQDKNA-QFYHHIKRHRVDPLPDWHGERIGSLKEYRKWLRDQSAY Punst1 LTWPEYLRIRANKRKWEMATTIPSTLFAGYFGNGI-DPMFFYGFSSVGIGGLGYLVG-PSIGSTCWRLYEARDK-EFYRHLVNNRVDPVPDYYGEKIGSLQGYRQWLRDQARY Rhior3 STWNDYFKLRKKRRTYEIVSYLPCTVTPAYFVQGM-DPLMAAIGATIGAGFGGFLLG-PVFGNTLFKLMDVRDK-EFYEHIKKNRADAVPDYYGEKIQSVHDYRSWLRKQREH Rhoto1 LDWPTYLSLRKSQRVYGLVASIPTTLIGGYFATGI-EPVYAYGLATLSCVGLGWLAG-PTVGGALWRLMEAKDK-DFFRHISRWRADPAPDYYAEKVGSLRQYRSWLRDQNIF Rozal11 ----------------------------------------------------------------------------------------------------------------- Sacce1 LTWSDFFKLRKQQRRINVGSSLFTALLGAYLSTGF-DPLTVISAGIIASGALGYLLG-PIVGSQVFKLFNNKNK-EFLKHIINNRVDAVPDYYGEKIGSLKEYKQWLRDCHAY Salro LPFNDYVKLRRKLSIRGYLFGVPCFFTGYVCATGL-DPMLFATLTTTLSGFVSFFVG-TALFKVLWRTLDANASGDFAQH------------------SIQKNRCAIA----- Schco3 LGWAEYFKIRRSRRLWQNIMTVPTSIVGLYFGSGL-DPFMFYGICTAGCMGIGFLFG-PTVGTALWRLIDARDR-EFFEHIARNRVPAVPDYYGEKIGSVHQYRQWLKDQAKY Schpo1 LNWPTFLKLRKSRRIFETLTSIPTALTGAYFLTGL-DLFTLYVIGTIASGGLGWLLG-PSIGRKIWTLIAAREQ-EFYRHLVKNRVTPIPDYYGEKIYSLSDYRRWLRDQKAY Sorma LDWNTFFKLRKTRRRVQLVFSVIMTLVTAVLSTPL-EPMFAIGLMTASFGALGWLMG-PAMGGMVFNAMAIKES-QFFARIKKHRVDPVPDFYGEKISSVAGYRQWLKDQRAF Sphar MPFEEYRQLKKSLKTRGRIFGVPTGFGSFAILSGM-DPMVATVLATSVMGGVGYVMG-GAMYGLVWRLISLRDE-DFLNRLDKYRFSDEDDYYGDKIITVADYRAWLKDQ--- Spipu1 IPWREYFSLRKSRKNWERAGAITGGTGGYYFGTGMQDPTLVYVLGAMAVAGLASFTG-IVGAGQLWRLLDLRDR-EFFHRIQRHRPKEMPDYYGEKINSVADYRSWLKKQRRF Sporo1 LDWPTYLSLRKSERLYGLVASVPTTLLGSYFATGI-QPVYIYGIATIGCIGLGWLAG-PILGGTIWKAIEAKDK-DFFAHVVKNRADAIPDYYAEKVGSLKDYRHWLRDQRTF Stehi1 LSWPEYLNIRKKKRRWELALTGPCMLLGAYFGSGI-DPMFVYGGATVGCVGVGYLMG-PVVGSYFWRMIEIKDR-EFHNRIVKNRVDPLPDFYGEKIGSLHQYRHWLREQTKY Tapde11 LPWNDFLHLRRQRHHAELIASVPSALLGSYFATGV-DPLILYGGATVACGGLGWLVG-PVFGSTAWKIIEAREK-EFYEHVKKNRVDPVPDHYAEKIGSVADYRRWLKDCRAY Thetr ----------------------------------------------------------------------------------------------------------------- Treme1 LSWPQYLSLRRQRRLWSTLTTIPTTFAGGYFASGI-EPMYVYGGATLGCMALGYLVG-PTIGSSLFSLLEVMDR-EFYHRFTRKRVDPAPDFYGEKIVSLSTYRRWLRDQAAY Trire2 LDWNSFFKLRLRRRRIQLLFSVITGLAGVVLAEPL-DPFFTLGIMTMACAGLGWLIG-PTIGNQVFYLMLQKEA-EFFARIKRHRADPVPDFYGEKIQSVAGYRRWLKDQRAF Umbra1 QNWDDYFKLRAKRRNYERICCIPSSITATYFTQGM-EALPVYGMATVLAGFGGFLAG-PFIGSGVFKLMDHLDR-VFYEHIKKNRADAVPDYYGEKIKSVSDYRSWLRKQREH Ustma22 LSWDKYLQLRRSRRLAGMVTTIPTTLLASYFLTGL-DPVYINAGLTLACTGLGWLIG-PTVGNSIWGLIAQKDH-DFYEHIKRNRVDPVPDYYGEKIGSIKQYRQWLRDQAAF Walse1 MTYTNEIIDR-----YDNIASIPTTLTGSYFSTGI-EAVWVYSFASVSCGALGWLTG-PTLGTAVWKFYEIKER-VFYHHIMKNRVDPVPDYYGENVYSLQTYRQWLRDQATY Zygro1 LTWANFFDLRKKERRINIGSSAFTAFLGVYLSTGF-DPLIVISSAIVASGFLGYLMG-PVIGTQLFKVFEIKNK-EFLRKVVANRVNPVPDYYGEKIGSIKEYRQWLRDCHAY [Cluster2599.fasta_al_trimmed; alignment length = 118] Allma1 ---------------------------------------------------------------------------------------------------------------------- Ashgo11 IIFLKNKVPIITNCLVVTSQRTVECPVFVVGRATTGNGVLL-LLLVGEIRRDIIKKRL-ESAELVEEIITYRTWVVLFSPQGTNELLPLLKIAAIGPTTAQYLLTSPKPEPSSLYNAI Aspfu1 ILLLKTKVPVLEGGLIFTSQRAVEGILYTVGPATAGDGQKL-LFLVGEQRRDIIPRTL-MDESLVDELVVYETWVVVFSPTGCDAMLRVLFIATIGPTTRDHLVCAEKPSPEGVGAGI Aurde31 VLLLKSPTPVLDSGVTVTSARAAEAPFYAVGDSTSGTGEAL-LELVGDKNKDTLPSIL-RAAGISQRLQVYGTWIVLFAPSATQFSLPFLRLATIGPTTATFLVAAPKPDAIQLAAAL Batde5 AVLFKDTVPVLQMGLIFTSKNAALAPVYSVGASTTGNAAEL-TFFVGDKTRDVLSVQL-QSALILQCIKVYEMWLVFFSPSGIDVVLQHGHIACIGKTTADHAAVATRPTPDMLMDAI Botbo1 VVILKNPVPVLNGAVVVTSARAVEAPFYAVGPSTAGTGENL-LYLVGDKTTDVVPRVL-KDGGFTLYLQVYSTWIVFFAPSAAKSALPILRFATIGPTTATFLVISPRPDAASLANAI Botci1 TFLLKTKVPVLEGGLIFTSQRAVELPIYTVGPATSGNGEAL-LFMVGEQRRDIIPRTL-MDPELVDELVVYGTWVVVFSPTGCDAMLRSLFIATIGPTTRDYLVCAEKPSPEGVIEGI Caeel ---------------------------------------------------------------------------------------------------------------------- Canalb1 VILLKNAVPLLTPIFIITSQRAVEMIGYTVGPATAGNGSKL-VFFTGVIRKDIIPRKL-IDSGYFQEFILYQTWIVFFSPQGTKEIVNYLKIASIGPTTRDYLVIAPKPDPEALFETI Cangl VLLLKNMLPLITDFLIITSQRSIECPTYTVGPATAGNGMKL-LFLVGEIRKDIIPKYL-RPRNFVDEIIMYKTWIVVFSPQGMSDILQYMKIACIGPTTCEFLLVSPKPDANSLIAAI Capow VVLLREAVPVLEAGMVLTSKRAVQAVWMAVGEATSGTGEAL-LFPCGEKRHDAIPKAL-AAAGILSEIVVYQTWFVFFSPSGLSSSLSLVRFAAIGPTTASHLATAPAPNADSLLVAM Catan2 ---------------------------------------------------------------------------------------------------------------------- Cioin IVLMRASIPVLSSGIIFTSKRSVEAPCYAVGESTSGNAQVL-LFICGQLKRETLPSVL-TCNEIFHTITAYETFITFFSPSGHRFC---FKIVAIGETTAHSFVTAERPNPESLFKII CocheC53 ---------------------------------------------------------------------------------------------------------------------- Coere1 VVLFRDPIAVLEAAMIFTSQNAVHAPVFVVGRATTGKASAL-LFFCGDQRRDTLPKGI-AESNKLVEMISYTTWMVLFSPSGARVVAPILRMAAIGHTTASELVKANVPNEHGIRNAL Conco1 ILLLKD-IPVLAWGFIITSPRASKAPIFVPGEGTTGNADNL-LFLVGDKTRPTLPNKM-NEFSIFDKFQVYQTWVAFFSPSGIDFSYDILKIAAIGETTKLHLACPLKPNAKDLAHAI Conpu1 VLLLRNPLTVLESGVIVTSSRACEAPFYVVGETTSGTGERL-LYLTGDKNRDTLPTVL-EGGGVLQHLQVYATWVVYFAPSSAEFTTTFLRLAAIGPSTANAVVLPEKPSPESLASAI Copci VLLFRDPVPVLESGMVITSKRSCEAPFYVVGEGTSGTGEQL-LYLTGDKNRDTVPTLL-TKGNIFESLRVYETWITYFAPSSASFVFPLVRIAAIGPVTSTHLVVATNPKPEDLVSAI Croqu1 VILVKHPLPVLDAGVVVTSARSAEAPFFAVGPATAGSGQML-LYLTGAHQHPGLSGAL-SSAQPFVEFQVYTAWAVFFSPNSASIGFPRLRFAAIGPSTCDALAVAKRPQPDSLLEAI CryneH991 VILFKTPIPVLQEGVIVTSRRGMEGPLFSVGHASPKSAGPL-LFLCGDKSLDEMPTAL-RNEGRVNEVVVYATWLAFFSPSSAAIVMPQIRVFAIGETTKKYLAVADRPDADGTFEAI Crypa2 ILLLKTKVPVLEGGLVFTSQRAVEAPVYSVGPATTGNGDNL-LFLVGEQRRDIIPKTL-MNPELVDEVVVYGTWIVVFSPTGCDAMLQVLFIATIGPTTRDYLVCSKKPSPEGVLEGI Debha1 VLLLKNQIPLLERNFIITSQRAVECIGYTVGPATAGNGLIL-VFFTGKIRKDIIPKNL-KLANIIMERVIYRTWIIFFSPQGTELIIEKLYIGSIGPTTEDYLIVSKKPEAASLFELM Dekbr2 IILLKNKLPLSKKALIITSQRCIETPSYTVGPATAGNGAIL-LFLTGKIRKDTIPKKL-REAEFMKELVSYKTWLVFFSPQGTEDILNRLNLATIGPTTEHFLVVSKKPNAKMLYESI Dicdi IVFFKSPIKVL-FGIILTSSNSI--HIYLIGETSESNATDL-LYFCGNQRREELPLYL-KNNNILKELVTYQSWLVFFSPSGVDFVLETIKVAAIGKTTENCLIVSPFPNAESLFSAI Dmel VIIFKSEVPTLSAGIIFTSPRCVEAHNYAVGEVTTGNARAL-LLPCGNLATDTLLSKL-AENGFVDACEVYETFLAFFSPSGVNCAQQYFKLVAIGPSTRRALCTAERPTVEHLVKVL Enthi ---------------------------------------------------------------------------------------------------------------------- Falba VVFLRHPIPLLRSAIILTSIHSVTAPIFAVGPATSTTGGQL-LFPCSSIRREELATKL-ARLPVLTEVRSYETWLVFFSPSGADPIIRPFQLGSIGSTTTRELSTATSPTPAGVAAAL Fomme1 VLLLRAPVPVYEMGVIVTSKRSVDAPFYAVGSATSGTGEQL-LFLVGDKTRDALPTILSADDTILDSVQVYATWIALFAPSGADYAVPYLRIAVIGPTTATHVVVAAKPSADALADAI Fusgr1 ILLLKTRVPVLL-----------EAPVYSVGPATTGNGAAL-LFLVGETRRDIIPKTL-QDGALVNETVVYGTWIVVFSPTGCDSMLRVMFIATIGPTTRDHLVCAESPTPRGVLDGI Galma1 VLLLREPISILETGVIVTSRRSCDAPFYVVGQTTSGSAASL-LYLVGDKNRDTISRLL-SEGGVLESVQVYKTWIVYFAPSAAALVTSILKVAAIGPTTNAFLAMAQKPTPEDVVSVI Ganpr1 VFLLRSPIPTLAWAVVVTSKRAVEAPLFTVGKATPGNATLL-LFLAGDKRLPTLPETL-QSAGFMEELEVYRTWIVAFSPSGISVALSHPKFACIGETTAAAVCVARKPTAEGVVEAM Gloin1 ILLLKEKLPLLERGVITTSQRAVEGPYFVVGKST-GSSEIL-LFLVGDKRKDYLPNKL-VESGFLKELLIYETWVVFFSPSGVDISLELLKIASIGKTTSNHLVNITSPKPDA----- Hisca1 ---------------------------------------------------------------------------------------------------------------------- Klula1 VILLKNKVPLIRKYIIITSQRTVECTIYTVGPATVGNGALL-LFLVGEIRRDVIPNRL-NSHGYVNEVVTYRTWVVFFSPQGTEEIISFLKFASIGPTTKQYLVVSNKPEPVSLFNAI Lacbi2 VLLLREPVPVLERGVIITSRRVCDAPFYVVGQATSGTAEQL-LYLTGDKNRDTLPNIL-PGGGILHPLRVYETWIVYFAPSAAEFVTPILKIASIGPTTATFLAVASKPTPEELVSSI Lenti61 VLLLRSPIPVLETGVIVTSGRACEAPFYTVGQATSGNSEKL-LYLTGDKNRDTLPSIL-KDAGILDNLQVYATWIVYFAPSSAQHVSPILL-AAIGPTTSAYLVVAAQPNPDALVEGI Malgl1 VLLLRQPFPILTDGIVLPSQRAAQAPFYVVGPATAGNAESL-LYLVGDKRSSSLLDTL-RAHHALHELLVYETWIVFFSPSGGNYALPELKVACIGATTAQWVAIAARPTPDALRSCI Mellp23 MLLVKHPMPVLDGGVIVTSARSAEAPFFAVGPATAGSGKSL-LYLTGAHQHADLSNTL-SSSEPFVEWQVYTAWVILFSPNSASLAFPQLRFAAIGPSTRDSLAVAPRPQPDALLEAI Mnele ---------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------- Morel2 ILLLKEPVPKVEWAFAVTSQNAVSAPIYCLTGATFDNAAQL-WFLTGETRMKTLAEKL-SAHQRFREVVVYETWLVGFSPKGVDLTVPVLHWGSIGPTTATRIAVAKSPKPAALAEAI Mucci2 VVLFKKKIPVLDCAMVLTSQRSVEAPLYIVGPQTAPRASEL-LFLAGDKRREIIPEAL-SAAHILREIKSYVT--------------------------------------------- Mydma IVLLREEIPVLCSALVITSKHATYA-IYVVGKSTSGNADQL-MFVCGNLARETIPDKL-RNFGLVETISCYKTVIVFFSPSGVKFYFSEIKILSIGQHTADCIAIAKRPTPDSLLEAI Neucr2 VFLLKTKVPVLEGGLVFTSQRAVEAPVYSVGPATTGNGETL-LFLVGEQRRDIIPKKL-MDPALIKEVVVYGTWVVVFSPSGCDGMLSALYIATIGPTTRLHLVCAEQPSPEGVWQGI Orpsp11 ---------------------------------------------------------------------------------------------------------------------- Pench1 ILLLKTKIPVLEGGLIFTSQRAVEGLLYTVGPATTGTGENL-LFLVGEVRRDIIPKTL-MDKALVEELVVYETWVVVFSPTGCEAMLRVLFVATIGPTTRDHLVCAPKPSPEGVLEGI Phybl2 TWVFKVKIPVLDLGLVITSQRAVETPIFVVGPRTADMATEL-LFLSGDKRRDVIPRRM-AKASIVHEIKAYETWAVYFSPSGIRYVCQSI--AAIGPTTAEYLVVADHPDAVHLVNSM Picst3 VLLLKNALPLLTPVFIITSQRAVEMIGYTVGPATAGNGLKL-VFFTGVVRKDIIPRKL-MEWNHLQETVIYTTWIVFFSPQGTELIVEYIKLASIGPTTEEYLITASKPHASSLYEAI Plicr1 VILLRAPVPVLETGVIVTSGRSCEAPFYVVGPSTTGTSERL-LYLTGDKNRDTLPTIL-RDGGVLDALQVYGTWIVYFAPSAAEFVTPFLKIAAIGPTTAQFLVVPPKPTPEDLSNAI Polpo SSKSNDPQTVLNDCLLVTSINAIHTQFLFVGESS-TNARSLILYLCGNLRRDELPSML-VEPAFLKELVVY--------PSGVSHSTVKL-ILSLKSGDKQSF--------QQLFNLN Pucgr2 IILIKTPISILRDGVVLTSARSVDSPFFVVGTSTAGSGHKL-LYLVGSHQDSSLSENL-SKHNNLVSQRVYSIWLVFFSPNSTNDLLLQIKVAAIGATTATFLVVPDKPNPASLLQAI Punst1 VLLLRAPIPVLEAGVVITSARACEAPFYVVGEATAGTAETL-LYLTGDKNRDVLPKIL-AEGGLLDSLQVYGTWIVFFAPSSAGYTFPFLA-AAIGPTTTAFLVESPKPTAEDLAAAI Rhior3 ------------------SQHSAEK-----------------LFLAGDKRRDLIPQAL-DKANIFRELQSYATWAVYFSPSGLKFIKSS-KIAAIGPTTADYIVVAEKPDPQHLINAI Rhoto1 LVLVRTPLPVLSDGVIMTSARSVEAPFFVVGNPTSGTGKKL-LYLTGDKNRDTVPRIL-EEGGVPETLQVYATWMVLFSPSGSKECLAELRFAAIGPITQQFLAVADKPEPEALVRAI Rozal11 VILLREDIPALEDVLVVTSPRAAIIKIYAMGYKTTKDAKEL-KFLCGNNRRDVLPSVL-KSAGFVDEIVLYESWVVFMSPMGVKSFFRNVEIAAIWSSTKAALGTPEVPTILSLLECI Sacce1 VLLLKNKVPLIKNYIIITSQRTVESTVYTVGPATAGNGSIL-LFLVGEIRRDIIPKKL-HSKGIVREVVTYKTWVVVFSPQGTKEITQYLRVASIGPTTKKYLVVSPKPDPKSLLDAI Salro VVVLKEEVPVLQAGIIITSSNAITAPGFFVGDKTANKAKEL-IFLCGDPHRPELPTLL-QAHSILHEVVCYSSILVIFSPSVARRVNALLRMVTIGPTTAAEIFVAEKPTPAHVAHAL Schco3 ALLIRAPVAALDDGVIVTSSRACEAPFYAVGRATSGTGEQL-LYLTGDKNRDTVPSIL-TEAGIFEPLQVYGTWVVFFAPSSTDFALPYLRIAAIGPMSSEHIAVASKPSPAQLVEAI Schpo1 ALLLKTKIPVLRCGLIVTSQRVSETPIFTVGPATCGRGEVL-LFLVGEKHRDIIQRKL-GDDRVTQELENTETWIVAFSPTS---ICSL-KIATIGPTTGDYLVVSPAPNPESLASSI Sorma VFLLKTKVPVLEGGMVFTSQRAVEAPVYSVGPATTGNGETL-LFLVGEQRRDIIPKKL-MDPALIDEVVVYGTWVVVFSPSGCDGMLSALYIATIGPTTRLHLVCAEQPSPEGVWEGI Sphar ---------------------------------------------------------------------------------------------------------------------- Spipu1 ILFCRGRVPVLGGGFIATSKRALEAPFYVVGKAT-GTADVL-LFLAGDKARDVLPQRL-SAANILEKVMVYRTWVVFFSPSGVDVALASLRCASIGPTTSRRLAEAGTPCPEALLAAV Sporo1 ---------------------------------------------------------------------------------------------------------------------- Stehi1 VLLLRAPVPVLEGGVIVTSSRAAEAPFYAVGPSTSGTAEKL-LYLTGDKNRETLPEIL-REGGLLGSCKVYETWITYFAPSAAAYVTPSIRIAAIGPTTADFLVVPHKPGAATLCKAI Tapde11 ---------------------------------------------------------------------------------------------------------------------- Thetr IVLAKSAAPMLAVGVVMTSAAAVAAPAWTLGYATAGTASKL-AYLCGVKRRASLESGL-AEAGLVAAVEVYDAAVVFFSPRGAAAVVHSLVLVAIGPTTAAAIATASEPTPAGVLAAL Treme1 VILFRTPIPVLMDGIIISSKRSAEAPLYCVGNSSSKSATTL-LLLRGDKTLDEIQKVI-REEGNVHEVEVYRTWLGFFSPSGAEVGLPFLKVVVIGHTTEEYLAVAETPDVEGIVNAI Trire2 VLLLKTKVPVLQGGLIFTSQRAVEAPIYSVGPATTGNGDAL-LFLVGEQRRDIIPRTL-TDPSLVTEEVVYGTWVVVFSPTGCDSMLRGLFVATIGPTTRNYLVCAETPTPEGVLEGI Umbra1 ILLLKEKVPVLEAGMVVTSKRAVDAQVFTVGPST-GCAQRL-LFLVGDKRRDELPMMM-KNASIMDEILVYETWVVVFSPSGLDILYHHLRIAAIGQTTSKHLAVADKPDAYYLREAV Ustma22 ILLLRSPLPYSARGMIVTSQRAVEAPFFAVGPATTGTGEAL-ENLATPAAAGASPQMIASPARI---------WIVFFSPSGVNYALDEFRIAVLGSTTRAWMAVATKPGPKELKDAI Walse1 VLLFKEEIPVLRDAVLVTSQRAVQAPFYSVGPSTSGNGNQL-LYLVGDKTASELSNIL-QDHGVITRLQVYATWSVIFSPSGANVIVPAIKLASIGPTTTRRLAMPARPDARQLTEEM Zygro1 AILLKNKIPLISQDIIVTSQRTVECTVYAVGPSTAGNGSIL-LLLVGEIRRDIIPKKL-SSNGIVKEVITYKTWVVFFSPQGTEEIIESIRVASIGPTTEEFLVVSLKPDERNLVNAI [Cluster2600.fasta_al_trimmed; alignment length = 292] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTPLYILVNLLTTYRPYQVLPQRTHPTMNMS--GALVVATKV Ashgo11 LVLNQHIL--VRLPSDNLKIVELKPNGISLGKFGA-CHVNPLGTTFEI--ESSKTNMELLDLQKLDHKEIERMKQDVDSIISMMIQSHETFHKKTIHSQEKYLKRKKQKF-AKFFTLGSSGLLRYLIEKGDMQRIMDLSEESLGMALNLANIRSNGTYLCMDE-TGGLIVYAMLERMFGGTIVVVHENEH-PNLDLLSNYSEEVKTVSKKGAYYRRITYDALIVASLSTLVPRLAGKVHGSRPIVCYSETLLELFLAPTLLETCRPYQTVRGKLHPLMTMR--GYLLWCHKV Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 IASGHTVL--LKLPSGEIRSAKLEGKGVQLARYGQ-FKAAPHGLSYEILGDVDATNENIV-DQSVSHAEIEALKASGEDIIQKQIQQHTAFGLKTAFSKDKYRKRKEAKY-SKRFTPTLHTVAAFLF-NKDNQRLRDLRPDALAHVLTFANVAPGRRVLVVDD-VAGMLVAGVMERLGGGRIITITDIESPPSYNALFNYDPDLASINQRQRLNKRGEFDALLVACPMSVIRHLSPYLRMSAPIVVHSEPLTAAWLGPSVHAPMRQHQALPGRTHPMMSMS--GYILAATKV Batde5 IQENQWII--IKLPSGNHKVFTLKANEVDLGKFGS-FQSNYQLVPYEIQNMELASNQMIM-DQKLSQKEIEELKVKSDSLIRSLVENNSAFDKKTEFSKVKYIKKKQRKF-SKVFTPTARVFCDIYL-EKNPEKTREIRIDTLSQMLTLANVKAGSSFLVVDD-MSGLLVGAMLEKMQGGKITVLHDKDS-AVLNLVMNFPSEVYTLP------KRGGFDGLLVASAHEIVKKLEGYLAPSKPMVVYSESLLNAFVNTQLTESLREYQ-VPSGTHPMMTTS--GYLFNSTVV Botbo1 IQLSDNVM--LKLPTGEIRCVRMDKKGVNLGRFGN-FKTEPYGLTYEILEDTDATNELINDDQPLRAEEIETLKQTGSDIIQKQIEQHANYALKTEYSKDKYKKRKEAKF-AKAFTPTLFNVCEYWF-TKDPSKIRDIRSDTLAQILNLANIRPGGRYLVVDD-ASGLLVAGILERLGGGKLLAIADVECPPAFHVLMNFSPELSSITEKVRLEKRGEWEGLIISTPFSVIEKLESYLAGSAPIVVHSQVLTELFLGPSITESLRQYQVLPGRTHPMMSMP--GYILSCIKI Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel IKSGEYLIV-QKIDGEQSRIVRFTPKQILIEKLK--FVADPHGL-FEVTEPSEPSALKLE-PQKLEMDAVLEMKKQGQEMVAKLVEGSASFQTRTVFSQSKYIKRKAKKH-SDRVLPTIRLLAKAYY-LKDPDRLAMLRADQLALILQMAGLHHGKNVVVFEQ-TLGLITSAVIERLGGGACIHIHRGAVAQSIPCVMNYDDNIKCVLDLEALARREQIHSLIIGSPISVLELLYPKLAPSGTIVIYSNILISATINLVLTDQCRVMQVLPDRTHPLMAQHV--HILTGIKV Canalb1 IQSGQHVL--IRLPSEGLKIVHLQDTGIGLGKFGS-FEVSPLGTSFEIFSDSAENNQNIINIQKLSKDDIDELKKSGQMIIEKMIAGHEGFDKKTIFSQQKYLKRKQQKF-LRRFTLGGSELLQYYI-EKDLNRVLDLSVETLGLMLTYSNVRPGGKYLIIDE-TGGVLTYAMMERMNCGTIVSIHENEH-ANLIALSDYGNEVKSVNNKSQYKKRGNFDAFISVSMSEVLEYVLPKIGGSRPIVVYNESLLEVVLAPSIYETVRPYQTIPGRMHPVMTNR--GYILWGTRV Cangl IVQDQHVI--LTLPSGNSKIVELKPDSVSLGKFGA-FQVNPLGTTFEI--LSSATNQGLINIQKLTMHDVERFKQQSNEIITKMIESHGSFHQKTIYSQEKYLKRKKQKF-AKFFTLSSSMLLKFLVEKGDIQRVLDLSEESLGMILNLTNIRSDGTYLCMDE-TGGLIVYTMLERMFGGKIVVINENEH-PNLDLLSNYSEKVVTLSKRSAYSRKQQYDGLVVASLPSLVPRLAERVHGARPIVCFSETLLELYLAPTILETCRPYQTARGKLHPLMTMR--GYLLWCHRV Capow AE----------LATGSHMAVALHEDGIHLVQRGN-L---PCDSYYEVTEESSVSNQFLV-DQKLTADDVQSMKRANQTLISKLVENSSSFEHKTEFSQAKYIKKKQQRH-LNVVRPTAQTLCEALF-ITDNSKIMSLRIDSLAHMLTFGNVFSGIRVAVVEG-THGLLSGACLERMGGGTLLQLHHSDV-PSRQFMFNFDEKLTTLSKRN-GRPRGRFDCLLQATPASLLFPMLPFLLPSRPFVVFCEPLVECAVNVQVVEVFTDHQVLPSRSHPNMTTS--GFMLSGTTV Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin MADNE-----------------INLNTVILERNSV-LKAVNYGTVFKVADDAQGDNRSLVDTQTIKRENILEMKGEGEEIVKCLVENSSSFNEKTSFSQNKYLKKKKKKYLS-YIRPNSRLICQLYQ-EREPAKICNMRMETMSQILTAANIKHGCNVGVVET-CSGVVLGSVLEKLGGGCVVNLHNGESPPNLFAIFNFPE------GKKRRENRKLLDAVVVVCPTPILLCLL-DLQLSRPFVVYSEPLMELAINLQLTDTTRQYQVLPERTHPHVMMS--SYLL----- CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 VEARSHVI--IVMPSLNSKMVCVKPDTISLGKFGS-FNANPFGHTYEIADITEANNRNIV-DQKLTFEEIEVLKEKSQDIIDSLMENNEGFAMKTEFSKSKYIKRKQKKF-MKSFITTVYNVCDYFF-KSNPFKTRNIRTDTLSQVLSLANIYARARVLSVDD-GQGMLTSALLSRVSEGLVFGVHDGDV-SNYDVLMNFSTELRTLSEASGHARRGEFDALVISTPKSVIKKLVPYLGGSRMLVVYDEPLLEAFLNVQMTESLREYQVLPSRTHPMMNMS--GFILSAIHL Conco1 IKHEDQLI--IQLPSGNLKLVTVRSDNIDLGKFGK-FQSNPYGYSYRIVEETAANNKNLL-AQKLSFEEIESMKANISDILNAMIANHSEFNNKTEYSKAKYINRKKKKF-NNIFTPNHYNICKFFF-DKNPSKIRELRIDTLSQILTSANIHAKSKVLVVDD-TQGLIVGSIMERLAGGKIVAIHESEF-PNYDIVFNFPQSLFTISLVKKYERKGNFDCLIISSPWSVISKLKRFIGPSRPIVIYNEPLTATFIYTQLSESLRHHQVLPGRTHPDMSMS--AYLLSCIKV Conpu1 IQSGHTVL--FRLLNGETRGLKVDHGSVSLGRLGS-FPANRYGLTHEIVEDTDATNELIT-DQPLTITEIEALKQSGADIIKAQIEQHANYELKTEYSKEKYKRRKEAKY-MKAFTPTLHNVCEYWF-KKDHNRIRDLRPDTLSQMLNLGSIRPGGRYLAVDD-ASGLVISAVLHRLGGGRLISICDVDSPPAYPVMMNFAKDLGTLNHRQRLDRRGEFDGLLVSTAFEVVQTLSPYLAGSACIVVQHQPLTELYLGPSITESSRRYQVLPGRTHPMMSTS--GFLLHAIKV Copci IQHGNTIL--VRLPNNDLRSVKVEKNTCEVGRRSS-PSAE---------EDTDATNELIN-DQPLTVEEIKALKQSGSDIIQKQIENHANFNLKTEYSKEKYLKRKEAKY-SKCFTPTLFNVCEYWF-EKDQFRIRDIRMDTLSQILNLANVRPGGRYLVVDD-ASGLIAAGVLTRLGGGRLLAICDTESPPAFPVFMNFDQNLASLNQKSRLKKRGEFNSLIIASPMVIIERLYPYLAGSASIVVHSQVVADLYLFPSVTEGLRRYQV----------------------- Croqu1 ISPGDNLL--LQLPSGLVKPVRITANAINLGKFGT-FSADPYGLTYEIVEDIAATNENIK-EQKMTGTDIEELKKSGREIIERQIAQHAAFELKSEFSKEKYIKRKEKKF-LKKFTPTMMNITQYLF-ESSAMAIRGLRPDTLSQMLTLANVRPGWQGIVVDD-VGGLVVAAVVERLGGGTVLVINDADSPPDLHFLLNFPAPLRSLNESTRLSKKGAFEGLIVCSPQSIIDKLRSHLAGSASVVIHSSPLASVFIHVTISEPLRRYQVLPGRTHPEMNGT--PFLLSAIKV CryneH991 IKEGDTVL--LRLPSDLVKSVVVLRDNVQLGKYGA-FPASHYDITYEITEETQN-------KNKSKGKDIAAVSKSNDAVIDDIVETNEFIDDLSETEKTTLSHDEIAELRAQGFQPSIPNVLYHYN-LRSPQSILHLRDDTLSQLLTMANIRPGGRYLVVDD-TGGLITAAVLQRMGSGSILLFNESDSPPAWGILMNFSDRIKWLNIKAAAKQRGGWDGLILATPISVVARLTPYLLGSAPIVVYSQVLAELYLNDTLTESERTYQVLPGRTHPMMTTS--AYLWSATRV Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ISPNQHAL--IRLPSEGLKIIDLKPGGISLGKFGT-FAVDPFGQTFEILSNSSDNNQNIINIQKLTSEDVDKLKESGQRIIEQMIAGHEGFDKKTLFSQQKYLKRKQQKF-LRRFTLGSSQLLQYYI-EKDTQRVLDMSEETLGLLLNYANVRPGGKYLLIDE-TGGIILYAMMERMNGGTIVSAHDNEH-PNHIALSDYPEEVKSINKRAQYYRRGNFDGFISVSMPTLLPEIIPTIGGSRPVVIYSEALLETVLAPSIMETVRPHQTIPGRMHPVMCMR--GYILWGTRV Dekbr2 ISFNDYVI--LTLPSGATKIIEVRRDGISLGKFGI-FGANSYGQSFEIFS-SSEDNRNLVDKQKVTAEEIEKIKKQGNKLISKIIEGHESFDKKTVYSQDKYVIRKQRKF-SRRFTLSPSNLLNHMRNDREMDKIQGLSEEVLGMMMSHANVMPGGNYLVMDE-TGGIVVYAMLERMHGGTITLLHENDQ-PKIAHLTNYSEEVKPINRRKRYYRRGAFDGLVYVSPVGFVPKIINKIAGSRSIVVYSEILIGLILLPNIYESVRYFQTIPGRLHPTMTSV--GYFLSGIKV Dicdi IKEGDHVI--LDINNGEKFSVIVKLGSVKIGK-KQ-ILINSYYSSFQVLNQNDADNRNLD-QQKLTQEDINEMKQKGNTIIKTIVENSESFKTKTSFSQIKYLKKKIKKY-STIVKPTLKSLTEAYY-KKDSRKICGLRFDSFGQLLTLGNIRANSQVLVVET-CMGLVTGSIAERMNGGTILSAYIGKG-PSLSIVFGFNTDTSVLNAKTIINQRGGVWSLVIVTPLNILLSCWPYLNSSGSFVIYSQPLMEVAVNQQISEIMREHQVLPKRTHPMMGMD--GFILYGTKV Dmel IQLGDYIV--------------IQRQKTKLQKFGS-LDTTPYGSTFKMISSSGADNRDIR-DQTLKPEDIAQLREECSKIIEKLVENSKTFHNRTEYSQEKYLLKKEKKY-FEFVQPTIRLMLDIFY-RQDSEKVMGIRVDTLSQIISYSGVCGFGSYLLYESGTNGLLPAAMLNSIGAGTLVHMHPGNV-PQKQALLKLPLECVSVNKKPKLDESAEFDSLVVAAPSNILQALLPLVKPSRPVVVFSELLQETVTGLHLTSNLRTYQILPNRTHPEVNMS--GYLLTGYTL Enthi IQLGDYCI--------------LKRDEVKEGVKKR-FAKKSFGQWVEVINDGTIDNRNLQ-DQQLTDQQIVEMKQNGEEIIKELLSHSDTYEGKTAFSQEKYIKKKIGKH-VATFQASPINVCDYYN-LKGNFKAGRVREDMLSYIMFHSDLRE--SVGIMEN-CNGLILGSVLRAVTPATVLAPHFSES-PTDDCQ------EKLLH---------QVNSLIIVTPFETVKTLFPSLKKSGSLVVYCDKLARLIVYADVIEPTRTIQVLPNRTHPNVLMD--SYLLYGIKV Falba AQHGEYVL--LRLSNGSERVVRLHPD-LNLGRFGS-LDLYPL-ATEEVAADGRTDNRNLI-DQDLTQDDILKLKGEGAELIDAIIAGSKTFAEKTEFSQAKYIKRKQERH-LRTIQTSLMNVAEHYY-TRHPSRIMNIRPDTLSQMLSYANVQPGARVVVLDD-CGGLVTAAALSRVGDGLVVGL-------STQ----FEEPADQLDRKNLAERRGNFDSLIVAAPMEAVRLLVPLLAPSRPFAIFSSALAPTAINLQIHDTTREYQVLPGRSHPFMNMP--GFLLTGIRI Fomme1 IREGHSVL--FLLPSGEYKSVKLGKNSTSFGKYGS-FNSSPYGLSYEILEDTDATNEYIN-DQPLTSLEIEALKKSGSEIIKRQIEQHASYTLKTEFSKEKYKKRKEAKF-AKTFTPTLHNVCDYWF-NKDRSRIREIRPDTLAQMLNYAGVRPSGRYLVVDE-ASGLLVSAVLERLGGGKILTICDTESPPAYPIMMNFDEDLSSLNQKSRLNKRGEFDGLLIASPFSIVEKLCPYLAGSASIVVHSQVLSEVYLSPSITEGLRQYQVLPGRTHPVMTAT--GYILHTIRI Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 VQSGDQVL--VRLPNGDVKSVKVEENAVVIAKFGA-FHANPYGLTYEIVEDTDATNELIN-DQPLTVDEIQTLKRAGSDIIKKQIEQHANYSLKTEYSKDKYKKRKEAKY-SKVFTPTLFNVCEYWW-LKDQTRLRDLRVDSLSQMLNMANIRPGGRHLAVDD-ASGLLVAGILERMGGGKLITICHTDSPPAYPIVMNFDPSLISLNQKDRLNKRGEFESLVISTPFSIIERLSPYLAGSASIVIHSEVVVDLFLCPTVTEALRRYQVLPGRTHPMMAMS--GFILQAIKM Ganpr1 VGPDKWVY--IEMPSGNSKLAFLKTDSIKLGKFGS-FRASPYGLPYEIDEDPDASNKEIF-AQKLSNAEIQQMKNETETLIQRVAENNATFERKTQFSKAKYLKRKEQKF-GKIFRPTPSLLCQYYL-DMNPSKTKDLRPDSLSQMLSFGNVRSGANVAVVDE-IGGLLIGAVMERLGSGTVCAIYDGDT-ESYECLLNWKQKLHTLPKIERVKRRGGFDCLITASPSSIIQSLSHLIRGSGNLVVYSEPLPPAFVNVQLTETTREYQAKPGRFHPLMNTN--GWLLTAIRV Gloin1 ILDNQYIF--IQLPSGNIKVVKLQKDTVSLGKFGT-FHSNPFGHSYEIVDETDANNKEIL-DQKLSYQEIEKLKKQGQDIIKKMVEGHSAFDQKTEYSKAKYIKRKEAKF-SRVFTPTLYSVWEYFF-SKNPGKIRDMRIDTLSQILSLANVRAYTKMLVVDD-TQGLVITGVMERLGGGIVLGIHDGEN-HNYDIVMNFSKKLLTLSDLKYYLRRGEFDGLIVASPESILETLMPYVSGSRPIIIYHEVLINAFLNPQITESLRQYQVLPGRIHPSMSTS--GYLLHATHI Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ISPNQHVL--IRLPSDNLKIVELKANAVSLGKFGA-FRVNRFGTTFDI--NSSENNRGLINLQEMSMAEIEAMKREADAIISKMIESHKSFHQKTVHSQEKYLKRKKQKF-AKFFTLDSSGLLHYLIEKGDVLRVMDISQESLGMALNLANINSNGQYLCIDE-TGGLIVYAMLERMFAGKIVVVHENEH-PNLDLLSSYSDNVKTISKKSAYFRR-SFDGLLVASLPTLIPRLGEKIHGSRPIVCYSEPLLELYLAPSLLETCRPYQTVRGKLHPLMTMK--GYLMWCHRV Lacbi2 IQSGDMVL--VRLPNGDVRSIKPERDSVVIGKFGS-FFANQYGLTFEIVEDTDATNELIN-DQPLTLEEIQALKQSGSDIIKRQIEQHANYSLKTEYSKEKYKKRKEAKY-SKSFTPTLFNVCEYWF-IKDQNRIRDIRIDSLSQILNLANIRPGGKYLAIDD-ASGIVVSGILERLGGGKLITICDTDSPPAYPVMMNFKTGLASLNQKSRLNKRGGFDGLIVASPHSIIEKMAPYLAGSASIVVHTQVAADLYLCPTVTESLRRYQVLPGRTHPTMAMS--GFIMHAIKM Lenti61 IQLGHTVL--LKIPSGDIRTIKLEGNSINLGKFGQ-FPSSPYGLTYEIVEDTDATNELIN-DQPLTVDEIETLKKAGSEIIKKQIEQHANYSLKTEYSKEKYKKRKEAKY-SKSFSPTMFNVCEYWF-NKDQNRLRDIRPDSLAQILNLANVRPGGRYLAVDD-ASGVVVSAILDRLGGGRLITICDIDSPPAYPVMMNFRKEMSSLNQRNRLNKRGEFDGLLVASPFSIIDKLYPYLGGSASIVVHSQVVTNLYLGPTVTEGLRRYQVLPGRTHPMMNAS--GFILHVIKI Malgl1 IVPGMNVF--LRLPSGMMKLVTLEKGKVSIGKFGN-FDANPFGPTYEI------------------------------EIMHQAVAEA-----------------------LDAF-----HVATYNF-ERCPEKIRNMRADSLSQCLSFSNVQAGGKYLVVDG-IGGLLAGAVLERMGGGSVYLVHDTDSPPALELMFNLTSALKTLHERNRAKKKGEFDAAIIACTYSVIHRITPYLSGSANVVVHSQPLVETFVNVSITEPLRRYQVLPARTHPDMTTS--AYILHAIRI Mellp23 ICKGDNLL--LQLPSGLIKPVRITPNSISLGKFGV-FESNPYGLTYEIVEDILATNENIK-EQRMTNDEIEELKRLGREIIERQISQHAAFELKSEFSKEKYIKRKEKKF-LKKFTPTIVNITQYLF-DSNVTSIRGLRPDTLSQMLSLANVRPGWNGIVVDE-VGGLLVAAVIERLGGGSVLVINDADSPPDLHFLLNFPNHLKSLNEINRLSKKGGFEGLIVCSPISILNKLKSSLSGSASIVIHSSTLSSAFIHVTISEPLRRYQVLPGRTHPEMNGT--LFMLSAIRV Mnele IKHGSHVVF-LNSKTGEQKCVRLPRNSVYIKPLS--FQADRFGQKYQVLEHCGKTNEFIK-DQILSQNDIEEMKSKGDEIVKNLVENSTSFNVKTEFSKAKWLKKKINKH-QPNIIPSIRLFAS--------SSVSKLRPDVLAKIINNANIWSGSKAIVVEC-KDDLLTSVVSQRVGLGTVLQIFEQKL-PHIMYCLDFSQELKFLGQKNELGKREKFDSLVISAPFPVLELLWDSLRSSGNLVIRTSVVLQC---LSVVDQFREIQVLPGRTHPDMRMQT-GWVLAEIST Monbr -----------TLPHFGACLVDVKR--VRMGKI-R-FNSKAYGEFYRVNDDEDADNRGII-AQGLDDQAIQNLKSEGEALVQTLVENSKTFKQKHAFTREKYIKRKKEIH-VNAVQPTIRNLHDAFY-QHFPDKIASIRVDTLASLLMRANVQPHSRVVVFET-CSGLMTAAVARQLGAATIV--------------FSISE-LSTVLQRQALVDRGQCDSLIVAAPTNIVQSLLKLLAPSQPFVVYHELLVELSVNVNLAENLRYYQVLEKRTHPLMTTEP--SLLYGTTT Morel2 INAGEHVF--IKMPSDNVKCIVLKAGSVSLGKFGT-FKANAWGNSYEIVEETANNNREIV-DQKLTLDDIKALKSEGEEIVNKLKESHATFDKKTAYSQAKYLQKKGKKF-HKVFTPTAYSVNEYFY-VRNPSKIRDIRMDTLSQLLSYSNVHSGCKLLVVDD-TQGMIVSALAERMGGGTILGLYDGDN-PHYDIVMNFNQEIKVLSDLEGYHRRGNFDALIVASPESILEKLLPYVAGSRPVIVYHEALLETLLAPQLTESLRKSQVLPGRTHPEMSTW--GSLLTATKV Mucci2 IQAQQTVI--IEMPSGNAKIISLKPDTVNLGKFGT-FQSDPFGLSYEIIEETAANNQMII-DQTLTHEQVLALKEKGEEIIKMMVDSHSGFSKKTEYSKAKYIERKKKKF-MKTFTPTISTINDYFF-SKNPDKIKHMRIDTLSQLLSMANVHANAKLLVVDD-TQGLIVSSCLERMGGGQLVAIHEGDH-HNYDILMNFSKAFHPVPDTISYGRRGNFDGLIISSPETVIKELLQYVNGSRPIVVYSEVLLQTFLNAELTESMREYQVLPGRMHPNMNMSC--YLLSTLRV Mydma VESGKGVI--IK-KGNNLKYVYVSNSAVEKMENFF-FSCKPFGSAFKVLEDTSGDNREIQ-DQRLGKNEIEAMRDEGEEIVKEIVENSSTFQGRNIFSKSKYLKKKNKKY-IAHFVPTTRLLAEMYF-QKNPTKILELRPDTLAQILTYSNVQFGSKVLVLET-CQGLVAGSILERLGSGSILQIYQGSF-PVRIVMFNYSEVLEKLGKKNESEERNDFESLILVSPKLPLLTLLDYLPPSCPFVVYFEPLMECATNLELTESFRNIQVLPKRTHPEIVMS--GYLLRGIKV Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 MAPNAYIY--VLLPSGNSKIVQLKPNCISLGKFGS-FKANPYGITYEIGEVTTINNKDLN-DQKLSHQEIEQLKKELEHVIQAVLDNSVTFEAKTEFAKAKYIKRKERKF-TKIFTPTAKLLCEYYL-EIKPSKIRELRIDTLSQMMTLANVHAQSNYIVVED-IQGLLLGAVLERTGRGKVLAIHEYSQ-FNGNIIFNFDEEVMTYPKKERYIKRNKFDGLLIASTIDVIEKLKPYIGGSRAIVAYSETLLETFVNAQITENITSYKISPPGYNEGISSS--SFNIGIPNT Pench1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 --------------------------SVTLGKFGS-FQCNPFGLSYEI--ETAANNQNIV-DQLLSQEEVERLKEEGAEIIRKMIESHTEFDKKTEFSKAKYIQRKMMKF-LKVFTPTLYSITQYFF-NKNPEKIRHLRIDTLSQLLNHANVRANGKILVVDD-TQGLIISAVAERLGGGTLVGLHDGKD-SNYDVLMNFSKHVHTVP--RSYERKGEFDGLIISSPETVIKKLSKYILGSRPVVVYSEMLLDAFIQSDITESLREYQVLPGRTHPHMMTN--GYLLTGLRV Picst3 ITAYQHAL--IRLPSEGLKIVQLRPDGISLGKFGS-FEVNPFGQSFEIFSNSAEHNQNIINIQKLSNEEIDELKKSGQTIIEKMIAGHEGFEKKTIFSQQKYLKRKQQKF-LRRFTLGASQLLQYYI-EKDIQRVLDMSEESLGLLMTYANIRPGGRYLVIDE-TGGVILYAMMERMKGGSIVLVHDNEH-PNIIALSDYPEEIKTINKRAQYDRRGNFDALVSVSMPTLLEHVLPTIGGSRPVVIYNELLLETVLAPSIFESVRAYQTIPGRMHPLMTMR--GYVLWGTRV Plicr1 IQAGHTVL--LKIPNGDTRSVKTEQNSITLGRLGS-FNANPYGLTFEIVEDTDATNELIN-DQPLTLEEIEALKESGSDMIKMQIEQHANYSLKTEYSKEKYKKRKEAKY-SKSFTPTVFNVCEYWF-AKDQSRIRDIRTDTLAQMLSIANVRPGGRYLVVDD-ASGLVLAGVLERMGGGRVISVCDIDSPPAYPVMMNFPLSHSSLNQRARLNKRGEFDALLVASPYSIIDQLFPYLGGSASIAVHSQTLTDLFLGPTVTEALRRYQVLPGRTHPMMTTS--GFLLHAIKV Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ISAGDNLL--LKLPSGQTRTIKLTADSVSLGKFGK-FQTNPFGLTFEIVEDIEATNELIK-EQKLTNQEIEELKKSGREIILRQIQQHSAFELKSEFSKAKYIKRKEKKF-MKMFTPTIHNLSQYLF-ENHHFAVKGLRPDTLSQMLSLSNVRPGWKGIVIDE-IGGLLVAAVLIRMGGGTIFVINNADSPPDLHLLFNLSPSLKSLNK-----KKTGFEGLITCSPESIVTKLLTKLTGSSTIVIYSRPLSDLFIQITISEPLRAYQVLVGRTHPEMNGT--HFIFSAIKV Punst1 IEPGHTTL--LRLPNGEVRSIKLDGHSISLGRFGS-FAANSYGLSFEILEDTEATNELIN-DQPLTSEEIDTLKKSGSEIIKKQVEMHATYALKTEYSKEKYKKRKEAKY-GKYFTPTLFNICEYWF-AKDKTRTREIRIDTLSQMITLCNIRPDGRYLVVDD-AGGMVVSAVLDRIGGGRIFTICDVDSPPTYPVLMNYPKNISSLNQKSRLNKRGGFDGLLVASPLSIMDKLSPYLAGSASIVVHNQILADLYLGPTVSESTRRYQVLPGRTHPFMTTS--GFLLHTIKV Rhior3 IQVDEQIL--IQMPSGNVKIVNLKADTVNLGKFGS-FNSDPFGLSYEIVEETEANNQLII-DQKLTQEEVLKLKAEGEEIINKMVAAHSEFDKKTEFSKAKYIERKKKKF-MKVFTPSLYTITDYFF-NKNPEKIKHLRIDTLSQLLSLSNVHANSKMLVVDD-TQGLIVSAMLERMGGGQLVAVHEGDF-HNYDILMNFPKSLYTVPAKRSYLRRGDFDG----------------------------------------------------------------------- Rhoto1 IRQGDNVL--LKLPSGIIKPVKIQPNGISLGKYGS-FKGHAYGHTYEIIEETEANNEFIT--QALSFVDIKALKESGREIIQKQIEEHKTYELKTEYSKEKYMKKKEAKY-LQMFTPTVHMIAQYHF-EKQPSKTRELRPDTLANMLAMANVRPGSRLLVVED-IGGLLVAAAVERMGGGRICVINDADSPPDLHLLFNFSPSITSIHELHKLRKRGGFDGVLIASPLSVIERLLPSIGGSAPIVVYSQLLFSAIISPTITEPLRQYQVLPGRTHPEMQGM--SYILSMIRV Rozal11 -----MKL--VQITSKN----------ISLGKYGS-FNGSPYGTSFEIKTTKEAPNSELN-DQNLSYDDILELKKEGRDIVNEITESSDSFSKRTTFAKAKYIEKKKRKF-MRVFTTTAKNLCEFYF-SSSSYKIGDLRIDSLSQILNFANIHAGLRVLIVDD-FHGLLAGAVLERMNGGSIFVVGDHPS-STLDKLFNFDKDISYLSQVQKFEMSGDFDALIVFSPQSIINRLSKYIYPSRPLVAFSEVLSSSFVNVQLTESIRNYQVLPGRMHPTMTTS--AFILSAIKV Sacce1 IDFNQHVI--VRLPSKNYKIVELKPNTVSLGKFGA-FEVNPFGLTFEI--DSSATNQNLVNMQELTVEEIEKMKQESKEIIDKIIKSHKSFHNKTVYSQEKYVNRKKQKF-AKYFTLSSSNLLQFLIDKGDIQRVLDMSQESMGMLLNLANIQSEGNYLCMDE-TGGLLVYFLLERMFGGKVIVIHENEH-ANLDLLANYSEKVHTISKKNSYYRKFLYDGLVMATLPTLVPKLAEKIHGSRPIVCYGETLLELFLAPSILETCRPYQSIRGKLHPLMTMK--GYLMWCHRV Salro VADGEHVVVELLAQPEFIKVVRVSGTKERLGKVT--FSLQPFGAVYEVVEEGNLDNRHLR-DQGMSSTQIYDLKQQGEHVIKQIVESSKTFKSKTEYSQAKYLARKKRQH-LTDVRPTLPTLWRVYS-QKAPQKICFMRNDALAMLLLRANVRAGGRFLVMDT-CNGLVAAAMAQRVAA---------------------------------------------VETLNLLQ-------------------------------L------------------------GH-- Schco3 IQSGNTVL--LRVPNGDIRGIKIEQNTISLGRFGS-FHANPYGLTYEIIEDTEATNELIN-DQPLTAQEIHALRQSGSEIIKKQIEQHANYALKTEYSKEKYKKRKEAKF-SKAFTPTLFNVCNYWF-NKDQNRIRDLRPDSLAQILTHANVRPGGRYIAVDD-ASGMLVAGILERMGGGRLITICDVDSPPAYPVIMNFKPGLSSLNQKARLNKRGEFDALIVASPWSILEKLYPYLAGSAPIVFHSQVIVDLYLAPTVVEPLRQYQVLPGRTHPTMNTS--GYFFHALKV Schpo1 ISENSSVF--IKLPSDNVRFVTLKPNNIHLGKFGS-FLADHFDETFEI--EEKKTNQELNDCQLMTQEEIDELRANIEEAIKQLTNSSKTFEQKTLFAQEKYVTRKGEKY-LQRFQPCVEVVANYMI-EHDPYKILDLTAECISLMLTLGNVKPGGRYLVVDE-TGCMFLGSLIDRVAGCKITLVHPNEQ-PNSSCLQDFKEDLKTLNHRKRYETKGNYDALFILSPMSVLQHLLPKLGISRPFMVYSQVLVETVIMLDIHEITRPYQVLPERTHPFMTVR--GFVLSGIKV Sorma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar IGDSQ-----------------ENRDGVEVTKAGV-KAEVNY-KVVQVTEEHSGDHRSIQQDQKLSYEEITRLKKEGEDMIKLLVENSGSFENRTEFSQAKYIMKKQKRHLANTFSPTLPLLCDTTY-QFNPERIQNIRSDSLAQVLTQANVHAGSRVLLLES-CKGLVTAGVLERLGGGECVSLYVGDKPSHPY-VMNFDEKMSTLR-QQWLARRGSFDSAIMVSPEGVMDRLLPKLMHSGQLVLFSEVLVPIFVNASLFDTTRSYQILPQRTHPENNMT--GYVLSATYV Spipu1 IAENSWAI--VQMPSDNTKLVQFKANSVNLGKFGS-FHAKPFDMPYEVETEEGTTNKDLV-DQKLSQVEIEQMKADSENLIKTIVENSETFDKKTEFSKAKYIKRKQKKF-SKVFTPSARGLCEHFF-KDNPRRICELRVDTLSQILTTGNVRSGARYLIVDE-AGGLLTCALVERMQGGEILQLHDHET-NNVDLILNLPPSLKSLPILTTRAKRGGFDGLFIISIKEIIETLSPYLAGSRPVVVYSETMLESFVNAQLTESIREYQ-LPSGTHPLMRMS--GYILSAIRV Sporo1 IRENDSLL--IKLPSGVIKPAK--ASGVSLGKFGS-FKAKVYGQTYEIIEETAANNEHIT--QNLTFVDIKALKDSGREIIQKQIQEHTAYELKTEYSKEKYLKKKEAKY-IPLFTCSTHSLTSYNS-DRVPSKTRELRADTMANLLAMANVRPGSRTLLVEN-TGGLIVGACIERMGGGTLMVINDADSPPDLHLLFNFATSIRSIHELNKLRKRGEYDSLIVASPYSVIERLLPFLAGSASIVTYSQVLILP---------WLKLAFIP---------M--P-------- Stehi1 VKSGNTVL--LKLPTGDVKSVKIDKDSVSLGKFGS-FHANPYGLTHEIIEDTEATNELIN-DQPLTSVEIEALKQSGSDIIKKQIEMHANYSLKTEYSKEKYKKRKEAKY-SKSFTPTLFNVCEYWY-NKDQPRIRDLRIDTLSQLLNLGNIRPGGRYIVVDD-ASGMVVSAIIERLGGGRLITICDVDSPPAYPVMMNFPIELLSLNHKQRMNKRGGFEGLIVVSPFSIVDKLVPYLGGSASIVVHSQILTDLYLAPGITESLRRYQVLPGRTHPTMVTS--GYLLHTTKV Tapde11 IAENHSII--IRLPSGAYKLITVRPDSCSLGKFGT-FDANPYGYTYEIIEEEVGNNEFIVDDQVMSHQEIRALRDAGDALIEKLKQNNKSFDLKTEYSKEKYTARKMAKF-APRFTPTLFDVISFLT-DKDPEKIMNVNQESMAFMLSAADVRPGGHYLVVDD-VSGLLVAGLLE----ANVTMIHDTEH-ANIDSVPQFNSELKALNKESTHIKDTTFDGLLVMSPIGVLKPLLPRLGTSRKVVLYSEPLLA-LLMPSIKELAREYQVLQGRTRPVMTKR--GYVYHAIKV Thetr ISEGEQVV--LWSNKGFYMIKKASASTLRMGKKKNGATLAPYGSMFHLTEISAPDNRHIK--QTMSAEAIQAMREEGEEIIGQLVESHAAYDSKTAFSQAKYIVKKKQKY-EYVLTATAARVADALF-DRSPRKLCFLRPDALAYMLTAANVRAGASYAIVDG-TNGLLTGAVLERCGGGKVVNYGRCAS-PQ----------LHSLS--------GTAHGLLMVPPLPVLQAIYPILGLGEPFAIFFEPLVACAIALRLSHTLRPQQVLPDRTHPEVSFH--NFVLAGHKS Treme1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 IKADQCLF--LQLPSGNVKQITLKPDTIPLGKFGT-FKANPFGLTYQIIESTEANNREIF-DQKLTHEEIERMKRE-ESIIKKIIESHSSFEKKTEWSKAKYVQRKKKKF-SKEFTPTLYSVAEYFF-ERNPEKIGFLRVDTLAQILNFANVHAEARYLVVDD-TQGLLISAVAERMGGGQIMGIHDGLS-SNYDVLHNFSKRISTLPEKINYTRRGGFDGLIVASPMSILDRLLPFVAGSRPVVIYNEVLIDAYVGVQMTESLRRYQVLPGRTHPEMTTS--AYILSAYRT Ustma22 IASGSTVI--LKLPSGRTKAAEIMPGKVSLGKFGS-FQADPYGFTYEIIE-TEATNEHIN-DQKLTYVDIQALKEQGREIIEQQLAGSESFANRTVYSQAKYVARKEQKH-LKLFTPEFGNVCDFWF-DKAPDKIRWIRKDALSQVLSFGSVRPGGRYLVVDG-VSGLLVGAVLERMGGGTVIAINDAESPPSLDILFNLPTQLKVINDKQRDRKRGDFDAVLIACPMSIVRRLKPHLGGSSSVVVHSQPLVEAFINISITEPLRKYQVLPGRTHPEMTTS--SFILHALRV Walse1 ISEGDSVL--IRLPSLQEKVIKLSKNGANFGKFGK-VAFSPYGLSYEIIEDFEATNQFIEDDTLLGEAEIDALKKGGRQIIEQQIAAHGQFDLKTAYSKEKYLKKKEAKF-LKFITPTTFNVCEYHF-NKNPSRIRDLRVDTLSQMLTLGNIQQGGRYLVVEE-TSGLLTAAILERLGGGSVLLIHDADSPPNLDILMNLPEEVRHLNERDKILKRGDFDGLICASPYGIVDKLHSRLSGSAPVVLHHAVLTEAFLSPVVSESLRQYQVLPGRTHPNMQMS--AYLLHTLRV Zygro1 ITADQHVI--LKLPSGNWKIVELKPHTVSLGKFGA-FQVDPLGTQFEI--NSSANNMNLINIQAMTSEQIEELKRQSEEIVAKMIESHSAFHKKTLQSQEKYLNRKKRKF-AKYFTLSASFLLQWLLEKGDTQKVLDMSEETVAMLLNVANIRSEGQYLCMDE-TGGLLVYFMLERMFGGKIVVLHENEH-ANLDLLSNYSEKVKTVSKKNAYQRRSQYDALIIASLSTLVPLLAEKVHGSRPVVCYSEILLELFLAPSISETVRPYQSVRGKLHPLMTMR--GYLMWAHRV [Cluster2602.fasta_al_trimmed; alignment length = 123] Allma1 NTAG-IRVLISPR-LARPAISVPDVAAINGHAAIVFDKDNCLTAPYETSIKSFDECLRVFGKVAVYSNSAGTATKIEQSLGVPVLESIPKHFNQVVFVGDRVLTDVVFANTSIHTIRRMENWW Ashgo11 NLSG-TKLLVNPR-LCLPDIVVPTFADLPNIKAVVLDKDNCFAYPHEDRVDAWQRLRAAYPRLVIVSNTAGTARALERNTGVAVLNEVLRYLEEVAVVGDRLLTDMVMARCGVWVIVAFEKRL Aspfu1 NLRGFNTLLRNPS-QFLPHLTIPTFTHLPTIRALVLDKDNTLCPPKTTAFDKLSALRNSPTSILIVSNRAGSIEERLSPLRIPVFREVLDWFDEIAVVGDRLGTDVLMAAWSVWCLERMEIWI Aurde31 NWPA-TSVTLRPR-LIVPHVSIRDLRQLDGYDSAVFDKDNCLTLPLQDPLDAWAECKRAFGRVLVVSNSAGTAESVSHKLGVPVLRDVQKFL-NTVVIGDRLFTDVVLARTAVFVLRGVENSW Batde5 NFAG-LSLLRRPS-MAMPHLVVDDINSIPGFKAIAFDKDNTLAAPYVNQIDSWSDCLYTFGNVAIVSNSAGSASKVEQAFGVRVLQELVAHFHEIIFVGDRISTDILYATYAILIIRKLERLL Botbo1 GLAQ-TRVFIQPS-LIVPRVTVPSIRHLDGYRGAVFDRDNCLTVPHEDRLEAWRECKQVFGNVVIVSNSAGTAESLSHHLGVPVLPTIKRYFSELVVVGDRLLTDVLMANLSVWTLRAVERVL Botci1 ---------------------------------------------------------------------MGAAVEVEKSTGVTVLPDIMEYFDQIAVVGDRLTTDVMMANYSVWIFARLEQKF Caeel --------------------------------------------------------------------------------------------------------------------------- Canalb1 NLSA-TRLLYNPS-LCLPHITVKSFDQLVTIKGVVLDKDNCFAKDHDDKVQTWKKLKEIYPHLLIVSNSAGTAKTLESNTGINVLNEITQYFNEIIVIGDRLFTDMLMANWGCWILPKLERDL Cangl NFNA-TRVIYNHS-LCIPRLRIATFNQLPHIKVVVVDKDNCMALQDDDKVAKWEELKRVYQRVLIVSNSAGSAKTLEKNTGVPVLDEIIEYFDEIAVIGDRLFTDILMANYGVWIFSKLEKNL Capow --------------------------------------------------------------------------------------------------------------------------- Catan2 NFAG-IWVIRNPS-LARPCESVPDISHVNGIKCLVFDKDNCLTAPYADQAKSFQSCVELFGNVAIYSNSAGTAKRIESSLGVPVLESVVQHFRQIAFLGDRLLTDVVFANYSVHTIRRFENMW Cioin --------------------------------------------------------------------------------------------------------------------------- CocheC53 NISG-TRLLRDPT-LCLPQHTIPTFNQLPDIRAVILDKDNCFAAPHTDEIDHFTRLRAAYPKLLIVSNTAGTATLLERNTGVVVLDDVMAYFEHVAVVGDRLSTDVMMANYGVWV---QGRGF Coere1 NIAA-LKLLRKPS-LLMPQMVVSDIRAIPGIKYLVFDKDNCLTAPYIDQIHVWSQCLSIFSNILIVSNSVGTAERVERGLGVPVLAEILDALADIAVVGDRLFTDVALANVSIWTIRTLEHRL Conco1 NLNG-IKILTNPS-LLIPQIKVNNFAHINGIKLVILDKDNCITKPYSLELKPMSELKSNI-NVIILSNSAGSLESIESNLQIKVFEEINAAYSEIAMVGDRLLTDIMFANLGIHTIRNLEYKL Conpu1 NVPG-IQLLWNPR-IILPHVIVQDVRHIDGYRGAVFDKDNCLTIPYEDRLESWKQCKETFGNVLIVSNSAGTAESVSHHLAVPVLSSIRAYFDELIVVGDRVFTDVVLAILSILTMRFVEKQL Copci NIPG-LQLIFYPR-LVLPHISVKDIRHLDGYRGAVFDKDNCLTIPHKDTLEAWKECLETFGNVVI-------AESVSHHLRVPVLSVIRSYFHELIVVGDRIFTDVIMANLAIWTMRYLEESL Croqu1 NISA-ITAAFRTS-LLRPNFRVRDIRDCDGINGLVIDKDNCLTRPYEDRLSAWRECVATFGNVVVASNSAGLAETVATRLNAPVLREIEGYFPRLLIIGDRVSTDIILAGVGILTMRWAEARA CryneH991 QLSN-TTALFKPA-LLRPHLRVPSIANVDGFNAVVIDKDNCL--------KAWTDLLSAFRRVLVVSNSAGTAEAVSLSLRAPVLANILSYFLRILVIGDRLFTDTLLADLSIYTLRWLEEKF Crypa2 NLSA-SRLIANPA-LCLPHATISTFKDLPSIKAVVLDKDDCFAVPETSEVDRFNALRAAYPRLLIVSNTAGAASELEEATGVTVLAEIMDYFHQIAVVGDRLSTDMMLANYGVWVFSRIEQRL Debha1 NVSA-TRLMYNPR-LCLPHLTVKSFDNLPQIKGVVIDKDNCFAKDHDDKVETWKRLTQAYPHLLIVSNSAGTASKLEKDTGVTVLEEIRDYFNEIVVIGDRLFTDMLMANWGIWLFPRFERNL Dekbr2 NLSG-TRVIYKPQ-LCMPQVVISDFSKLQRIKAVVLDKDNTFAKPYDDKVAEWDHLKQCYPELLIVSNTAGTAEKIEKTIRVPVLREVMAYFKEVAVVGDRLFTDVMMANYGVWIVSKMEKHY Dicdi NIEA-IHVFLNRS-LIIPHLEVKDIRNINGFKGVLFDKDNTLTEPYKNEIESLNKCLEIFGNVVIISNSAGSANQIEKSLGIKVLDSVKNHFKNLIMIGDRYLTDILFGNLTIYTIRNKERQI Dmel --------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------- Fomme1 NVPG-LQLLFRPY-LVLPSVVIKDLRCLDGYRGAVIDKDNCLTLPYEDKLVAWEECKNVFGNILIVSNSAGTAESVSFHLGVPVLSAIRAYFNALVIVGDRIFTDVVLANLSVFVMRFLEKKV Fusgr1 NLSA-SRLIFKPS-LCLPHHTVSTFNDLPEIKAVVLDKDDCFAYPDSIEVTHFEKLRLAYPKLLVVSNTAGAAAEVEKNTGVMVLQEIMEYFGHVAFVGDRLTTDMMLANWGFWV-------- Galma1 NVPG-IQLLLYPR-LVIPALVVNDIRQVDGYRGAVFDKDNCLTLPHRDTLESWKSCRETFGNVLIVSNSAGTSESVAYHLGVPVLTAIRTYFHQLIVVGDRVFTDIVLGNLSILTMRWLELRL Ganpr1 --------------------------------------------------------------------------------------------------------------------------- Gloin1 NLNA-IKVFRKTH-LCIPHLIVNDIRNINGINALAFDKDNTLTTPYSDEISAWEESKKIFGNLIIVSNSSGTAEAIEKSLGVYVLQELLSHFHTIAIIGDRVFTDVLFGNFTVLTV------- Hisca1 NIPAFNTLFRNPS-LLVPNYTIPTFLQLPKIRALVIDKDNTLTPPESRIIQKLKDLRTNPSGILIVSNTAGSIESVLSHLKIPVFPSILAHLDEVAIVGDRLGTDVIMAGWSIWTLAKLEVRL Klula1 NLSA-TRLFKDPK-LCIPSIKYANFNEIQHIKAIVLDKDNCFAKPHDDKVEQWDKLKQLYPKLLIVSNSAGTAKTLEKSTGVPVLVEIMAYFSEVAVVGDRLFTDVVMANYSVWLFVLLEQQV Lacbi2 NIPG-LQLVLYPR-LVLPSIAVKDIRHIDGYRGIVFDKDNCLTLPHKDFLEAWKECREAFGHVLIVSNSAGTAESVSHHLQAPVLSAIRTYFEELVIVGDRIFTDVVMANLAIWTMRWFERSL Lenti61 NVPG-IHLLINPR-LVVPSIVVKDIRQLDGYRGAVFDKDNCLTVPHEDRLEAWKECRETFGNVLIVSNTAGSAESVTYHLSAPVLKSIRAYFEELVIVGDRVLTDVVMANLTVLTLRALEKGM Malgl1 NVPG-VQSIMRPG-LLVPHLRVACISHLNGARYIVFDKDNCLTVPHKDALAAWNECCAVFGNILLVSNSAGSAESVSSHLGVPVLRQVVEHFLHVLVVGDRISTDMVFSHTSILTLRALESSV Mellp23 NFSA-IKILIKSK-LIQPNFKINDIRDCNGFNGIIIDKDNCLTRAGDDRLHSWNDCLKTFGNVLV-------AEILTRKLNSTILHSIQSYFPNLIVIGDRFSTDIILGTLTILTMRWCEDRI Mnele --------------------------------------------------------------------------------------------------------------------------- Monbr NAPG-LAAVLRPG-LARPALRCQSIADVADYDVLIFDKDNCITTPYALEASAWQELRQ---RVYILSNSAGSARAVQTALGVPVIAEVMRYLDRIAVIGDRVLTDIVFANKAILVVRRLEAAL Morel2 NLQG-IRVLTSPR-LMVPNIVVRDIRDINGIIAIAFDKDNCLTKPYGLELDAWKSCRDVYK-VVIVSNSAGTAQAIEHALQVNVLEELLKHFGRIAIVGDRALTDVVFGNLTILTIRRMEHRV Mucci2 NLSG-VRVLLNPS-LAMPHMIVDDIRHINNIKAIGFDKDNCLTAPYVSTIEAWKDCVETFSNVLIVSNSAGTAQKLEESLGVAVLQCLKEKLDQTAFVGDRILTDVLFGNLTIWTASCVEW-- Mydma --------------------------------------------------------------------------------------------------------------------------- Neucr2 NLSA-SKLIAKPS-LCLPHATVPTFNDLPDIKAVVLDKDDCFAYPDHNEVERMEALRAAYPRLLIVSNTAGAASAVEKATGITVLDEIMSYFHQIAVVGDRLATDMMLANYGIWIWSRVERTV Orpsp11 --------------------------------------------------------------------------------------------------------------------------- Pench1 NLRGFNTLLKQPT-QFLPHLTIPTFTHLPTIRALVLDKDNTLCAAKTTSFAKLSSLRASPTSILIVSNRAGSLEAQLAHLRIPVFEEVVQWFHEIAVVGDRLGTDVLMAGWSVWCLEKMEVWI Phybl2 NISG-IRVIWNPS-LAIPHIIVNDVRNINGVQAIGFDKDNCLTAPYVSQIEAWIECKNTFGNVAIVSNSAGTAKKLEQSLGVPVLRELQKHFRQTVFVGDRIFTDVLFGNLTIWTLRRMEYRL Picst3 NVSA-TRLLYNPS-LCLPHVTLKSFDQISEIKGVVLDKDNCIAKDHDDKIETWKKLQGAFPHLLIVSNSAGTAIKLEKDTGVTVLGEIGEYFHEILIVGDRLFTDMLMANWGLWLFPKMERQL Plicr1 NVPG-IHLLINPR-LVLPALTVKDIRQIDGYRGAVFDKDNCLTLPHKDTLDAWRECRETFGNVIIVSNSAGTAESVTHHLAAPVLSSIRAYFEELVIVGDRIFTDIVMANLAIWTMRFLERRL Polpo NFEA-IKIIGNRS-LLIPHLEFKDVRSIDGFSAVLFDKDNTLTEPYADVIEAVDRCRGVFGSIAILSNSAGSATRLESTLGLSVLEKVKEHFQSIVMIGDRYSTDVVFGNLTIFTIRDKESRY Pucgr2 NLTA-IRCLLSPS-SLVPSLHVRDIRCVDGYIGVVIDKDNCITKPYHDQLHAWQSCLATFGGVLLVSNSAGTAESVARHLGVPVLKAIEKYFLKLVVIGDRVTTDIILASFSVLTMRWAENRA Punst1 NLPG-LQLLFNPR-LVLPALTVKDIRYLDGYRGAVFDKDNCLTLPSRDGLDAWKECRDAFGNVLIVSNSAGTAESVTNHLRVPVLSGIRTYFHELIVVGDRIFTDVVMANLAIYTMRWVEKTL Rhior3 ----------------MPHVIVKDMSCINDIQAIAFDKDNCLTAPYVSTIDAWKECKETFGR----------AQQLESSLGVAVLQYLSNFVEKVAFVGDRIFTDILFGNLTIWTT------- Rhoto1 NWSG-IAAIARPR-TLQPALVVPSIAHLDGVHAVVVDKDNCIAKPNEDDLRAWADLLETFGNVLVVSNSAGDAETVSRNLRVPVLRQIAAHFLRILVIGDRLSTDMIFSSVGVLTMRLVERLV Rozal11 NRQG-FKVYKSPS-LIVPCFQVKGIRSLAGIKAICFDKDNVLTAPYVSELNAWEECQQVF-KIAILSNSAGSASAAERSLKVPVIILIIRHFQKIVVVGDRLFTDILMGNLTIHTMRKFENTL Sacce1 NISG-TRLLYNPS-LCKPSLVVPTFNDLPSIKAVVLDKDNCIAFPHDDKIQHWETLRSKYSALLIVSNTAGSAKLLEDKTGIPVLNEILDYFKEVAVVGDRLFTDILMANYGVWILSKFEKKL Salro NIPG-IRAARDAS-VIAPHCAVTDIRQCNGYRYVIFDKDNCIALPYSNTLDAWAECLGAFGNVVIVSNSAGSAQSIEQGFGVPVLSDILHHFHRCVVIGDRLLTDVYMGKLTIHTVRRFENWL Schco3 NIPG-LHLLVNPR-LVLPSLVVRDIRQLDGYRGAVFDKDNCLTIPHKDHLDAWAECRAAFGHVVVVSNSAGTAEAVGHALGVPVLEDIRAYFDELVVVGDRVFTDVVMARLAVWTMRLMERGL Schpo1 NIEG-IQTIRNPR-RIIPHATFPTFSQIPDIRALVLDKDNCITLPNETTIKKIREFQNIYGNVILLSNSIGTAAHFQQKWNIPVVEELYTYLSQILFIGDRLLTDITLANWGVWLMMEVESWL Sorma NLSA-SKLIAKPS-LCLPHATVATFNDLPDIKAVVLDKDDCFAIPDHNEIERMEALKAAYPRLLIVSNTAGAASAVERATGITVLDEIMSYFHQIAVVGDRLATDMMLANYGIWVWSRVERSV Sphar NGTA-VDVMFKRQWLAIPHVTVTDIRYINGCRAVVYDKDNCITNPYEDHIPGWDECLRVFGNVLIMSNSAGSARHLDNVLGVQVVDAILQALEELAFVGDRLLTDVVFGNLTIHTVRTMENAL Spipu1 NFSS-LKIVRSPS-LLIPHLSVPDIRYINGIRAVVFDKDNTITAPYVEQVKSWESCKDTFGRLLIVSNSAGTAATVEAALGIPVLDALSSYFHCIAVVGDRAFTDIVYGNLTVHVIRKLEYPL Sporo1 NWAG-ISALVRPS-ILEPRLVVSSISQLDGVVGVVIDKDNCITVPHRDQLGSWQDLLDTFGNVLIVSNSVGTAEAVSRNLRVPVLGQIALHFLKILVIGDRLATDLILSHVGILTLRGLEKLA Stehi1 NLPG-THILVNPR-VILPSIAVADIRQLDGYRGAVLDKDNCLTIPHDDRLEAWKDCQRVFGNILIVSNSAGTAESVSHHLGSHVLSAIRKYFRELVVVGDRVFTDVVLARLAVWTMRWAESQV Tapde11 --------------------------------------------------------------------------------------------------------------------------- Thetr -----------------------DIKAIDGVRGVVLDKDNTITLPYSRTVNSVRAALSAFGNVVVFSNSAGSADSLSAMLGIPVLDALKAHFASYAMIGDRHLTDVVFGNLTIKTMRRYEAKY Treme1 PLPN-LSAIVRPR-LLRPDIRVPSIAHVDGFNAVVIDKDNCLTLPQNDDLEAWKELKRSFDRVLLVSNSAGTAECVTRSLRAPILPLIIQYFLKILVIGDRLFTDTLLAWISIHTVRLLETIL Trire2 NLYG-SKLLLKPG-LCLPHHIAPTFNDLPNIKAVVLDKDDCFAYPDAKEVQHFEKLKQAYPKLLVVSNTAGAAAEVEKNTGVFVLAEIMAYFSHIAVVGDRLMTDVMLANWAFWIFSRIDHCL Umbra1 NVSG-IRVLRNPS-LIIPHLVVDDIRQIDGVKVMAFDKDNCLTAPYENRIPAWKLCKDTFGRVIIVSNSAGTHQQI-----MPVLGALLERFREMAMVGDRLFTDILFGNVTVLTIRRFEHRL Ustma22 NLSG-VAVMVRPS-LVVPHVQVPDIRHLDGVRYLVFDKDNCLTAPHSDVLEAWQRCQRVFGNILIVSNSSGSAESLSRALNVPVLTEALEYFGSILLVGDRIMTDIVVAHISVLTMRRLERRA Walse1 SVAA-IRSAFNPK-LLKPSIRVD-----DGITGIVIDRDNCLTLPRQDYVSSWDDCKSVFGRCVILSNSAGTANVVSRNTGVDVLAPLEARF-NVAFIGDRLLTDVYMANVSI---------- Zygro1 NISG-TRVVYNPR-ICMPQLAVPTFNDLPNIKAVVLDKDNCFAYPRENQVDKWLDLKKKYPALLVVSNTAGSAQLLEKDLGTCVLQEVMKHFDQVAVVGDRLFTDVMMANYSVWIIVKFEKAL [Cluster2608.fasta_al_trimmed; alignment length = 96] Allma1 LPDRTWIDSFTTVSYARSSGPGG--QNVNKVNTKAILKWLPEYAINKDGDLVVMSDRFRSQRQNVDDCVEKEQKRHVKKLQNERRLESKKMAGKKK Ashgo11 AEMRGWLEQLHRAQYARSSGPGG--QNVNKVSTKCTLTWFPALVARAQDAVVVQCDQWRSRERNREECLRRVAEARHARLADRHRLHGKRRQGERK Aspfu1 TAAREWLNKFNEISFSRSGGPGG--QNVNKVNSKATLKLVPRILADRTQMLVIQSEESRKQAANVESCYEKEQREKVQKLENEARIKAKKLHSSKK Aurde31 RAARAWINEFRELSFARSSGPGG--QNVNKVNTKATARWIPEWASASSGSLLVSSDVTRSQSQNVDEALRKEVTDRVKGYQDFRRRTSKDYRSSVK Batde5 -----YI----SVQYSRSSGPGG--QNVNKVNTKVDIRWVPQPVMNKKGELVVTSDRFRTQHMNYNDCIDKSTLRRVDHL---------------- Botbo1 ALARTWVAAFKELSFSRSSGPGG--QHVNKVNTKATVRWMPVWAVPSTSSLLITSMQARSQSQNVDDCLLKEQRARVRALEKTRNKVVKKTRSDVK Botci1 EVARTWYSNFNETTYSAAGGPGG--QKTNKTSSKANTVILPLTILKNTDAIQIQCDSSRNRTDNKEETHRREQQQRVKHLANTARLKMKKQHGDKK Caeel ------IQASSEKRYTLSSGPGG--QNVQKNATKVEIRWLSESLINTAGELIIDSDRTRERHLNVADCFDKKDEKILRERATQHRLQEKRRTSEKK Canalb1 DKSKKWLESFTDISYSRSSGPGG--QKVNKTSSKATVSWIPQPITKGG-GLLIQSDTSRNREHNTELCFQREDKEKWQELYKERKKFNKKKQSDKK Cangl ASARQWVRELRRVRYDRSSGPGG--QNVNKVSTKCTLTWFPSEVYPANDKFIVRADETRSREQNRRLCLDKATVSKWDSITNKIRLEGKRQVSEKK Capow AVHHTWLRALSSVTFARSSGPGG--QNVNKVNTKVELRWIPERVITKEGEFHVTSTTHRTQLKNIEDAFEKEQQAKVRRLANERRMMEKKMHSSRK Catan2 -----WIDNFKELSFARSSGPGG--QNVNKLNTKVLLRWLPTYCINKAGDLLVSSDKFRTQRQNIDECIDKQQR--------------KKVAGL-- Cioin AYKSIYVGSFSKVEFSKSSKPGG--QHVNTTLSKALVRWIPFEVITRTGDLIVWDEESRYQMRNLQSCLAKSKEDRIAELAHKKRLQKKRKSSFTK CocheC53 DAARTWLAALHELTFSRSSGPGG--QNVNKVSSKATLKHVPAALAPRSNTIVVHADDSRKQSDNARSCYRREQARRVNRLNNERRLKTKKLHGAKK Coere1 ------------------------------------------------------------------------------------------------ Conco1 ------------------------------------MRWIPNYVVTKTGEYIISSERTRSQFNNLQDCVTKETLEKIDKL---------------- Conpu1 ------------------------------------------------------------------------------------------------ Copci SGVHKWAEEFKSLSFSRSSGPGG--QNVNKVNTKVSLRWIPQWAVASTHTLLVTSTFTRSQAQNIDDCLEKETKQRVAGLDKARKKAEKQHRSSVK Croqu1 ASARTLRARLLEQSFSRSSGKG--------VNTKASLRHLPAYWAPTSDSIIIQSSLTRSQASNLDDCWKKERAESVNR-EGMATKRFLVHKPPPR CryneH991 LLARQWVDAF-VATRSRSSGPGG--QHVNKTESKVTIRWLPKFIHHSPPSLLITSQTTRSASQNQANALNLEQKERVKELEKERRMEMKKRRSIKK Crypa2 AEARKWRQSVSTTTFARSSGPGG--QHVNKTESKAITTVLPKLLVRNKDGLAFHAQTSRDRDANAEENKSKEKKRKHQGLAREARLKSKKFQSSKK Debha1 SKAKEWMENFSEISYSRSSGPGG--QKVNKTSSKATIAWIPKPITKSG-GILVQSDSTRNRDTNTDECFRKEDKKRWQEIRKEKRLFNKKRQSDKK Dekbr2 NNVRQWLQNLKKVTYTHSSGKGG--QHVNKTDTKAQMSWMNENAFTISGDILVESQLTRYRDKNLQDCLDKETTKRTWARENEKRLHTKKHRQENK Dicdi SSSKFYQRNYSNLQFSRSSGAGG--QNVNKVNTKVEVRWIPPYVVNDDDEFIITSSKHRYQHLNINDAMDKEKERIATEIANERRLHDKSIKKEIK Dmel SLDKIYLQIYTEITYSRSSGPGG--QHVNTVNTKVDVRWIPEQTITKDGYFYIKSDLTRSQQMNLADALEKETLEKLRRRAVRERLQLKRGRAQVK Enthi ------------------------------------------------------------------------------------------------ Falba QFVSGWVKAFNVVKYIRSRGPGG--QNVNKVNSKADVRWLPRFVINSAGEFFVQSDTMRTQSANYQACLEREQRKKVDQLQNERRIQEKKRRASIK Fomme1 SRARQWIEAFRILTFARSSGPGG--QNVNKVNTKCTARFIPRWAVASTDTLLVTSTKSRSQAQNVQSCLQKEQKTKVAAFEKARRRQDKEHRSQKK Fusgr1 NEARSWYESFDNTTFARSSGPGG--QHVNKTETKAITAILPKSLTSANDSLTFQAQDSRSRDANADDNRRKEKRKKHEEIFHESRMKQKKFTSAKK Galma1 AEASGWLSRFSELSFSRSSGPGG--QNVNKVNTKATVRWIPRWAVASTHSILVTSTVHRSQSQNIEECLQKAQKKKIEGFANARRTMEKKKRSSVK Ganpr1 EK---------TIKFARSGGAGG--QNVNKVNTKVDLRWIPEYAVTKRGEYTLTSTRYRTQMENLDDALLKDTVKRIQEL---------------- Gloin1 EQAERWLKKFTTFTFARSSGPGG--QNVNKVNTKVDMRWIPEYALNKKGEFMITSDKSRSQVKNIEDCVDKETLKRIEQLENNRRRTDKQYRSERK Hisca1 AVARSWLSQLTDVSYSRSSGPGG--QNVNKVNSKVTLKLVPRALAERSDSLVIQSDETRKKTKNLDLCFEKEQRKKVQAL---------------- Klula1 AVGRAWIEGFKVATYDRSRGKGG--QNVNKVNSKCTLTWFPDEIAPSKDALVIQSDETRSREQNRDICVEKSTKRKWNEISNEVRLSEKKFKSDKK Lacbi2 AEARAWVEKFKEMMFSRSSGPGG--QNVNKVNTKATLRWIPEWAVASTHSILLTSTVHRSQSQNVEDCFNKEQKKKVEALDAVRRRAEKTHRSDVK Lenti61 DLARTWIEKFKEFTYSRSSGPGG--QNVNKVNTKATLRWIPLWATSSSQTILLTSTAHRSQAQNVQDCLAKVQQERVRQLEKARRRQDKDKRKEVK Malgl1 ------------------------------------------------------------------------------------------------ Mellp23 -----------LISFSRSGGKGG--QNVNKVNTKVTLKHIPNYWASTSNSIIIQSTLTRSQSQNLEDCWQKETIQRVKKLEKIKTLKQKNYRHQIK Mnele ------------------------------------------------------------------------------------------------ Monbr AYHLYWGNAAAQIQFARSSGPGG--QNVNKVNTKADVRWLPTEVINKNGELVVAVSDTRSQKKNLQLAMQRETKQRIKKLEDKRRLENKKKHAQKK Morel2 EKVENWAKGFTTLNFVRASGPGG--QNVNKVNTKVDMRWLPEYVVNKNGEYVLTSDRKRTQMANLDDCMDKETLERLERM---------------- Mucci2 KEATAWQHSFNSISFSRSSGPGG--QNVNKVSTKVDMRWLPEYAKSKDNEIIITSDKTRSQAKNIQDCYEKATLLRIEQL---------------- Mydma DIKEI-LKNVT-IRMVKSSGPGG--QHVNKTNSKVELRWLSEDLVNKNGEIVVSSDVDRSQHYNLEDAINKETKDRVNSYENESRIQNKKIHSMKK Neucr2 AEARRWHKSFHDTSFSRSSGPGG--QHVNKTETKATTTHLPKILTRGNDSITIQAQTERSRSANQAENHQKDKARKYEALARETRLKEKKFLSSKK Orpsp11 ------------------------------------------------------------------------------------------------ Pench1 QLARDWLKTLTEVSFSRSSGPGG--QNVNKVNSKATLKLVPRLIAERTQCLIIQSDEERKQSNNVESCFDKAQRNRVQKLQNEGRIKDKKKHSDKK Phybl2 AKATEWIKRLSQLSFSRSSGPGG--QNVNKISTKVTLRWIPAYA-TKTGDLIITSDRTRSQAKNVEDCYDKETLARVKHLEDTRRKDVKKRQSDKK Picst3 DKAKAWLQSFTDISYSRSSGAGG--QKVNKTSSKATVAWIPLPVTKKG-GILIQSDTTRNRDVNTDECFRKEDKKRWEEIAKEKRMFNKKKQSDKK Plicr1 AQARAWLGVFKELTFSRSSGPGG--QNVNKVNTKATLRLVPAWAASSSQSILITSTVHRSQSQNVDDCLSKQQKERVRGLDNARRRAQKDKRSQIK Polpo ------------------------------------------------------------------------------------------------ Pucgr2 SSARAHIDQLLKFNFSTSGGKGG--QNVNKVNTKATLKIIPAYWAQQTGQLVIHSSLTRSQSSNVDDCWTKEQTQKVNRLEKTRTKKLKNIRKDIK Punst1 NKARMWLDRFKELTFSRSSGPGG--QNVNKVNTKATLRWIPPWAAASSRSILITSTVHRSQAQNIDECLSKEQKERVRKLDQTRRRIAKAKQSCKK Rhior3 EEAYAWQRSFNTIAFSRSSGPGG--QNVNKVNTKVDLRWIPDYAKSKNDELIITSDKTRSQAKNIKDCYDKMTLERVRQL---------------- Rhoto1 KLARVWISAFEDISFTRSSGPGG--QHVNRTFSKAVVRLLPPYVSNSPPSLLVSSSTHRTQQTNLADCMSKAQKEKVKELEKLRTAKSKKMRKETK Rozal11 ------------------------------------------------------------------------------------------------ Sacce1 VQARNWVGALNILRYDRASGPGG--QNVNKVNSKCTLTWIPQEVAKGSDSIVIQSDETRSRETNKLKCFEKETSKKWNKIANKERLLDKKVHSDKK Salro QQAVVWLSSFQTATYSRSGGAGG--QHVNKVSTKVTLRWLTEEAMNKQGELVVQCQDTRSQNRNYDLAVQRQQQAKVKKLFNERRLKEKKKQSQKK Schco3 NDAKRWVQDFKDITFSRSSGPGG--QNVNKVNTKATLRWIPQWAVRATDSILLTSTAHRSQAQNIEECMRKEQKQRVKALNKERQKREKMYRSQLK Schpo1 NQLLKFHLKWKQISFSRSSGPGG--QNVNKLNTKVIVNCIPMFLYRIQNGIKIYSQKTRSQHKNIEDALNKEKIARISILSNEKRLSEKKYKQKKK Sorma AEARKWHKSFQDTSFSRSSGPGG--QH---------------------------AQTERSRSANQAENHQKDKARKYEALAKEVRLKEKKFHSSKK Sphar --------------------------NVLK--------------MNKKGEFVITSTKTRTQKGNIDDALLKEQKEVVRQLANTMRLKEKMFNKLKK Spipu1 EDIELWISRFSEVSFSRSSGPGG--QNVNKVNTKVDMRWLPPEVINKKLEFVVSSDRHRNQHQNFEECLSKETLKRIEEFEREKKMKAKERHAQKK Sporo1 ------VACY-ETSFARSSGPGG--QHVNRTLSKAILRFLPPFTSQSPPSLLISSSTSRSQSANLDECFSKQQRNRVEGLEKAKVEKIKKQRKDVK Stehi1 QAARGWLEKFKEVTFSRSSGPGG--QNVNKVNTKATLRWIPPWAVSSSHSLLITSTTTRSQSQNVDDCLLKQQKDRVRGLDKARRRADKDKRSQVK Tapde11 ------------------------------------------------------------------------------------------------ Thetr ------------------------------------------------------------------------------------------------ Treme1 SLARQWLDGF-EIKYSRSSGPGG--QHVNKTESKATIRWTPAFLLKSNPSLLISSQETRDRRENLRRALDIKQKERVRGLEKAKRRVDKTKRSETK Trire2 AEARLWYNSFDNTTYARSSGPGG--QHVNKTETKAITVVLPKYLTAGNDSLTFSAQAHRSRSANLDENRRKEKKKKHQDIFHEARVQDKKYNSAKK Umbra1 AEASKWCKSFSKITVSRSSGPGG--QNVNKVNTKVDIRWIPEYATTKDGQLIMVSDRTRSQAKNLEDCMEKETIQKVKQLAYMRRKDRKQLHSQKK Ustma22 QERRRWLSNFQQVSFSRSSGPGG--QNVNKLNTKANVRHPRKWLVASDHSLLITSMRHRTQEANVQDALEKQQRDRVRRLDARRKKHTKIKRADVK Walse1 -IAREWLKKL-DFTFSRSSGKGG--QNVNKTSSKATARWLPKYVVKSSDSVVVSDSSTRSAAQNSRIASHRGKAQRVDNFEKANMEKMKKYQKEKK Zygro1 QSASKWVEQLDAVRFDRASGPGG--QNVNKVNSKCTLMWLPQEVARSSDSIVIQASESRSRESNKKLALEKTTIAKWDQISHEKRLNNKKMHSDKK [Cluster2609.fasta_al_trimmed; alignment length = 146] Allma1 --------------------------------------------GVRYNAEKKKVG-NYYSTPIWSFRMKCHL--CNWIEIHTDPKNTRYVVASGAKQKPADAGPLFKLEELEELPYAMNQELRRKFREDKKEIQDRIGTIPILPE Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 --------------------------------------MPFAVWGVRFNAEKRKVG-NYYSTPVYSFRMKHGA--CGWIEIRTDPANTAYVVVEGGRKR--DAGAFARLERIEDLPYERSRRLRRTFRVERKALRDKMSLIELVEE Aurde31 KYYPPDYDGEKHGSLNKHALGVRARKID-QGILIVRFELPFNIWGVRYNAEKRKIG-SYYTTPIYAFRCKCHL--CGWFEIQTDPKNTRYVVTEGARQKPEENGPLAALERLEQLPYAHSLRVRKQFRAQKKAFKEKYGLLQLERD Batde5 KYYPPDWDPSK-GSINQHPLRDRARKLD-QGILIIRFELPFNIWGVRYNAEKKKVG-MYYSTPIFSFRMKCHL--CGRIEIHTDPENTEYKIISGARRRPEDIGSFYKLERIVSLPYTASQKVRKRFRV----------------- Botbo1 KYYPPDYDGEKHKSLNKHALGDRARKID-KGILITRFELPFNIWGVRYNAEKKKIG-NYLSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVVSGAKKKPEENGPFAAVERLSTLPYTLSTKLRRTFREEKKGVRDRYALLGLVPE Botci1 RYVPPDQEGLM--SGNKHALGARANKI-SQGILTVRFEMPYPIWGVRFNAEKKKVG-NYFSTPIYSFRIKHIT--CGSIEIRTDPKNTAYVITEGARKR---EDAFASLERLEELPHEANRKLRRAFREGRKALQDKMSLLDLLPE Caeel FYYPPDFNYKTHKSLNTHALRERAKKID-QGILVIRFEMPFNIWGVRYNAEKKKIG-MYYTTPLHEFRMKCHL--CNYYVIRTDPKNFDYELVEGCSRQPTDIAAMFKKERVDKLDFTANSFLRAQFRNEKKNLRDKLSITQLLPE Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------- Capow KYYPPDWDPSK-GSINQHPLRDRARKLS-EGILIVRFELPFNIWGVRFNAQKKQVG-KYLSTPILSFRMKCHL--CNWWTIQTDPKTHNYLVMEGARRRAADIEPMYKLEHIDELDFDLNSLARKRFRQDKAAFRSSTRLIPAAPE Catan2 KHFPKDFDPAKHNSANVHALGKRARKLKSDGILIIRFELPFNIWGTRYNAEKKKAG-NYYSTPIWSFRMKCHL--CNWFEIRTDPKNAEYEIVEGARKRPEDAQPLYRLERIAELDFSSNQLLRRKFRAEKKSVADRIGTLPILPP Cioin KYYPPDFDYKKHGSLDSHPLRERARKLKSEGILIIRFEMPYNIWGVRYNAEKKKIG-NYYSTIIYKFRMKCHL--CQHFEIQTDPANCDYKILSGARRKAKANEPMFKLESLSELDYLLNKALRNKFRSEKKALLDKSSLIKLLPE CocheC53 RYYPPDASNPP--SFNSHPLGKRANKI-SQGILTVRFELPFAVWGVRFNAEKKKIG-NYYSTPIWSFRMKHSA--CGWWEIQTDPKNSEYKVVEGARRRPGDKGAFASLERVEELPYDVNARLRKDFRAKRKGIQAKFSLLDIADE Coere1 KYYPPDWVPSK-GSANQHPLRSRARKLD-QGVLIVRFEMPFNIFGQRFNAEKKQIG-NYYSTSIWSFRMKCNM--CQWLEIHTNPKDATYDVVRGARKKPEED-RIHKMEQLNILPDSANAQLRKIFREGRKEIRSRTGILPILPA Conco1 --------------------------------------------------------------------------------------------------------------------------MRSIFRKGRKQLKDKYSLIELEPE Conpu1 KYYPPDYDPEKHKSLNKHALGDRARKLD-QGILITRFELPFNIWGVRYNAEKKKVG-SYYSTPIYSFRCKCHL--CGWFEIQTDPKNTRYVVVSGARQKPEENGPLAALERIQQLPYSASLRVRKRFRAEKKQLKGKYALLQLLED Copci --------------------------------------------GVRYNAEKKKIG-NYYSTPIYSFRCKCHL--CGWFEIQTDPKNTRYVVTSGARRKPEEHGPLAALERIEALPYTLSSKVRRRFREEKKSLKGQYGLLKLLDD Croqu1 RYYPPDFDPKTHDTLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKVG-MYYSTPIFSFRCKCHL--CNWFEIRTDPQNTRYVVVSGARQKPAENGQFALVERLEDLPFVLSQKLRRSFRKEKATLRTRYSLLRLDEK CryneH991 RYVPPDYDPKKASTLNKHALGKRAKDID-KGILVVRFELPFNIWGVRYNAQKRKVG-NYYSTPIWAFRCKCHL--CGWFEIRTDPKNAAYVVEEGAKKKPEEHGPIAHLERLTELPYAVSAALRKKFREEKKAMKERYGLVDL--- Crypa2 RYVPPEHEGVL--SANGYALGARASKLRTEGVITVRFEMPFAVWGVRFNAEKKKIG-NYYSSPIFSFRIRHAV--CGVIEVRTDPKNTAYVVVSGGRKRAADESAFSNLERIDEIPYARNQALRKSFRVGRKDIKERLGLIELLPE Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi KYYPPDWDPSK-GSINQHHLRDRARKID-QGILIIRFEMPFSVWGVRFNAEKKTVD-KYFTSNIYSFKMKCHQ--CNQFEIQNDPKNTDYKLISGLKKRPEDSETLLKLEQLEKLDYQLSSIMRKSFREKKK--QKSKGIIPLLKE Dmel KYYPPDYDPKK-GGLNTHALRERARKI-HLGIIIIRFEMPYNIWGVRYNAEKTKVG-MYYTTPVFKFRMKCHL--CNHFEIQTDPGNLDYVILSGARRQPLQNEAMYKLEVLQKLSYMANSRLRAEFRQQKKQLLAKSSLIALLPE Enthi -------------------------------------------------------------------------------------------------------------------------------------------------- Falba KYYPADFDPAG-GSLN-HRVQPRDSRTG----AIVRFELPFAVRGVRFNARKFLTGRRYHSTAELAFRLRCALTGCGEFIVRIDAAKRDYVVDEGARRVPADGSLLQAVEELTAIPLDDARDLRASFRQDRHRSLRAAGLVALASS Fomme1 KYYPPDYDPSKHTSLNKHALGDRARKLD-KGILITRFELPFNIWGVRYNAEKKKIG-NYYSTPIFSFRCKCHL--CNWFTIETDPKNTQYIVTSGARKKPEENGPLAALERIEALPYTLSLRARKRFRAEKKAVKGKYALLTLVAD Fusgr1 RYVPPDVEGTI--SANKHPLGARASK---PGSLTVRFELPYAVWGVRFNAQKRRVG-SYFSTPIWSFRFKHVE--CGEIEIRTDPKNTAYVVVAGGAKR---EDAFASLERIDELPYTQNQKLRKAFRVGRKDLQDRMSLIDIMPG Galma1 RYYPPDYDPSQ-GSLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKIG-AYYSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVTSGARQKPEDNGPLAALERIESLPYSLSMKARKRFREEKKIIKDRYGLMNLLEE Ganpr1 KYYPPDWDPSK-GSINSHPLRERAKRLKTEGILVIRFEMPFNIWGVRYNAQKKKVG-NYYSTPILQFRMKCHL--CNWIEITTDPKNAEYVVTAGARRKAEDAEPMYRLEVLERLPYALNYRLRAAHRAERKAVATRLGLIPVLPA Gloin1 KYYPPDWTPEK-GSVNKHPLGDRARKID-QGILIVRFELPFNIWSVRYNAEKKKIG-KYFSTPIFSFRMKCHL--CNWIEIHTDPKNAEYLVVSGARKKPEDSEALYKLEILTQLPYTHSQRMRKKFREEKKEICDRNALIPLLPE Hisca1 RYVPPDQEGLT--TGNKHPLGARARHLHTTGELTVRFEMPFAVWGVRFNALKKRVG-NYYSTPIYSFRMKHTV--CGWIEIRTDPKNTAYVVTEGGRRK-LDKGAFSKLERMEELPYEQSRRLRRVFRAERKALQDRMSLIELLEE Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 KYYPPDYDPSQ-GSLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKIG-AYYSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVVSGARQKPEENGPLVALERLESLPYSLSLKARKHFRQEKKLIKDRYGLLSLLED Lenti61 KYYPPDYDPEKHSSLNKHALGDRARKID-QGILIVRFELPFNIWGVRYNAEKKKIG-NYYSTPIYSFRCKCHL--CGWFEIQTDPKNTRYVVVSGARQKPEENGPLAALERIEALPYEHSRRVRKRFREQKKEVKSAYGLLALSAD Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 RYFPPDFDPKKHDTLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKVG-MYYTTPIYSFRCKCHL--CNWFEIRTDPQNTRYVVESGARQKPAENGPFALVERLEDLPFVLSQKLRKSFRKEKASLRNRYSLLRLDE- Mnele KYYPPDWDPSK-GGLDQHPLRERASKL-HLGILVIRFEMPFNIWGVRYNAEKKKIG-MYYTTPIWQFRMKCHL--CNYIEMHTDPKNFDYIVASGGRRKQNDAEPMFKLQIIDKLDYLLNRSLRKRHREDRKFLKNKMGLLKMLPT Monbr KYYPPDFDPAVHGSLNVHALRERARKI-TQGILIIRFEAPWNFWGVRYNAEKKRVG-NYYTTPIWAFRMKCHL--CNHFVFETDPKNCDYKITEGARRKPATTQAMYRLEQLLQLDYDTNAALRRSFRAEKKVLKERAGILELLPE Morel2 KYYPPDWDPSK-GSINQHPLRDRARKLD-QGILIVRFELPYSIWGVRYNAEKKTIG-KYYSTPILSFRMKCHH--CSWFEIQTDPKNTAYKVTAGARRKAEDRGKFAKLEVLTKLPYALSQKLRKEFRMER-ALADKIGVFRILPE Mucci2 KYYPPDWTPEK-GSINKHALGDRARKLD-EGILIVRFELPFNIWGVRYNAQKKQIG-KYYSTPILQFRMKCHL--CNWIEIHTDPKNTAYVVVSGARKKADDTEPMYRLEHLTQLPYTKSQQLRRQFRQEKKKVRDKHSLIELLPE Mydma KYYPPDYDPSK-GGLNTHALRERARKL-HEGILIIRFEMPFNVWGVRYNAQKRKMG-NYYTTPIYKFRMKCHL--CQHFEIQTDPKNCDYLLLSGCRRKTEAAGAMFKLETLTLLDFRINQLLREKFRNEKKAFKLKSNLLTLVKE Neucr2 KYVPPDAEGVY--SGNKHPLGHRASKLASQGILTVRFELPFAVWGVRFNAAKKKVG-NYYSTPIWSFTIKHGQ--CGEIEIRTDPKLTRYVVVSGGRARTDEESAFGKLERIDELPYARNQKLRKAFRVGRKDLRERMGLIELLPG Orpsp11 ------------------------------------FELPYNILGNRYNAEKKKIG-MYYSTPIFSFRMKCHL--CNWIEIHTDPKNTEYVIVSGARRKAKENGAFYKLELLTKLPYTSSYIIRKKFRNSKKKMKSISNLLNMIKQ Pench1 RYVPPDQEGLT--TANKHPLGARARHLHTTGALIVRFEMPFAVWGVRFNAEKKKVG-NYYSTPIYSFRMKHTV--CETIEIKTDPQNTAYVVTEGGRKR--DKEPFSKIERILELPYEKSKRLRRTFRQERKALKDKMSLIELLDE Phybl2 KYYPPDWTPDK-GSVNKHPLGDRARKID-QGILVVRFELPYNIWGVRYNAEKKKIG-NYYSTPILQFRMKCHL--CGWIEIHTDPKNAKYLVISGAKQKPEDSEPMYKLEVLTQLPYSQSQQLRRRFRQEKKRLRDKHSLIPLVPI Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 KYYPPDYDDEKHKSLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKIG-SYYSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVTTGARQKPEENGPLAVLERLESLPYTLSTKVRKRFREEKKQIKGKYALLGLVPD Polpo KYYPSDWDPKH-GSINSHPYGKRARKID-QGILTVRFEMPYNVWGVRYNAEKKQAG-KYLSSKIWSFKMKCHL--CNYFEIQTDPENTEFKMVSGLRRKDESAIPIYRLETLTRLDYELSSMMRKSFREQKK--QESRGIIDLLPI Pucgr2 RYFPPDFDPKTHDTLNKHALGDRARKID-KGILITRFELPFNIWGVRYNAEKKKVG-MYHTTPIYSFRCKCHL--CNWFEIRTDPKNTRYVVESGARQKQEENGAFAQVERLEELPFALSQRLRKTFRKEKAQLRSKYSLLKFIEA Punst1 KYYPPDYDPQKHSSLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKIG-NYYSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVVSGARQKPEENGPLAALERLEALPYAHSQRMRKRLREEKKAIKNKYSLLTLIRD Rhior3 KYYPPDWTPEK-GSINKHALGDRARKLK-EGILIVRFELPYNIW------------------------------------------NTAYVVVSGARKKPKETEPMYRLERISQLPYTKSQKLRRRFREEKKKIRDKHSLIDLLPE Rhoto1 KYYPPDYDPNEHKSLNKHALGKRAHKID-QGILVVRFELPFNIWGVRYNAEKKKVG-NYYSTPIWSFRFKCHL--CGRIEIQTDPQNTRYVVTEGAKQKPAENGPFASLERLSALPYAASTALRSSFRKAKKGTRGKFALLRTPAR Rozal11 RY-----NESQSIALSSTTMAPETSKID-ENIIIERFENPFNIWGVRFNSEKTKVG-YYFSTPIWHFKFHCPT--CGWLEMESDPKNAVYVCKSGCRKKREDSEAFYRLEVILELDYSISKMLRSNLRSQKKSFRNRTGLCPIAKE Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------- Salro KWIPPDFDPKKTSSINSHPLRERARKIK-QGILVIRFEAPWNFWGVRWNAEKKKVG-AYYSTPIYAFTFTCHL--CNTIVFETDPKNCDYRITKGGRRKADDAQPMYMLERLVRLDYDINSKLRNSFRQEKRALLSKASLIKLVPE Schco3 KYYPPDYDGEKHKSLNKHALGDRARKLD-QGILITRFELPFNIWGVRYNAEKKKVG-NYYSTPIFTFRCKCHL--CGWFTIQTDPKNTRYVVTEGARQKPEENGPLAALERLEELPYALSRKVRKHFREEKKEIKDRYGLLARARE Schpo1 KYIPPE---------------NAKRKFD----NVIRFEMPFPVWGTRFNAVKKEIG-SYYTTKIWSFSLKCHL--CNPIDVHTDPKNTEYIVASGGRRKPAKAEAIEALEVINFIPFVSSQRLRKQFRERKKSLKNRAALIDILPP Sorma KYVPPDAEGVY--SGNKHLSVNAASKLASQGILTVRFELPFAVWGVRFNAAKKKVG-NYYSTPIWSFTIKHNA--CGEIEIRTDPAKTRYVVVSGGRARGGGESAFGKLERIEELPYERNRRLRKAFRVGRKDLKERMGLIELLPS Sphar ------------GSINSHPLRDRARKLD-QGILIVRFELPYNIWGVRYNAEKKKVG-MYYTTAILSFRFKCHL--CNWMEMQTDPKNTAYVCVS--------------ETK---------------------EEREKLA------- Spipu1 KYYPPDWDPSK-GSINQHPLRERARKLD-QGILIIRFELPFNIWGVRYNAEKKKVD-MYYSTPIWSFRMKCHL--CGWIEIRTDPKNSEYVIVSGARKRPADIGAYEALELLTLLPYALSQIMRRKFRTEKKAVAEKFGLVKVLPV Sporo1 QYYPPDYDPNE-GSLNKHALGDRARKLD-QGILIVRFELPYNIWGVRYNAEKKKVG-MYYSTTIWSFRCKCHL--CHWFEIRTDPQNTRYVVHEGARQKPEENGPFASLERLSAMPYSASLALRDSFRKKKRRVREKFGL------ Stehi1 KYYPPDYDGEKHKSLNKHALGDRARKID-QGILITRFELPFNIWGVRYNAEKKKIG-MYYSTPIFSFRCKCHL--CGWFEIQTDPKNTRYVVTEGARQKPEENGPLVALERLEQLPYSLSRRVRKHFREEKKGIKARYGLLVLIRE Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --MP------------EEEAKAAMRR---QPTISVRFELPWSVWGSRATATKDHVG-FYYTTPVFTFTFPCPL--CAPMVLATDPKHRDFAVITGGRRKPTRPPAIASLEALEAAPLAAA---RTAARSRRHA-------VRLATP Treme1 RYVPPDFDPRQNSTLNKHALGKRAKDID-KGILIVRFELPFNIWGVRYNAQKKKVG-NYYSTPIFGFRCKCHL--CGWFELRTDPKNAAYIVHEGARKKPSANGPFGHVERLTELPYLVSSALRRRFREEKKGLREQYGLVDL--- Trire2 RYVPPEHEGTT--SGNKHPLGQRARKLASQGILTVRFEMPYAVWGVRFNAEKSRAG-NYFSTPVWRFRFKHAE--CGWIEMRTDPKNTAYVVVEGAKKR--ENAAFASLERIEDLPYALNQRLRRDFRKGRKDIKDRMGLMELVPE Umbra1 KYYPPDWTPEK-GSVNKHPLGDRARKID-QGILVVRFELPFNIWGVRYNAEKKKIG-NYFSTPIWQFRMKCHL--CNWIEIHTNPKETKYDVVSGARQKPEDSEAFFKLEVLTQLPYTLSQQLRRKFREQKKKLKDKMSLIDLVDE Ustma22 RYRPPDSDPRR-VRFNTDALASRARRLGTHAMLVVRFELPFHVIGTRFNAEKRPTD-WYLSTRIWTFTCKCS---CAKFDILTDPQNAQYTLGTGARRQPEQSAAFAKIERIIQLPYTSNAALRATLREQKTQIKRRIAWLHLSRT Walse1 --------------------------------------------GVRYNAEKRKIG-NYYSTPIYAFRCKCHL--CHWFEIQTDPKNTRYIVSEGAKQKPEEGEPFAAVERLSQIPYAMNQKLRAKHRVERRELKDRYALLQIIDD Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2612.fasta_al_trimmed; alignment length = 98] Allma1 HQLFFRPHRTVFVYNLPLKTLFQAYVIYKKATALLEERAKEVIAEYDEDG-FILVT-FYRFQMREEKRSRLLELREKFAQDKKKIEELKQSR-RFKPY Ashgo11 HYMYVKKHNCLFIVNLPIKESFGALLKFVDQASLLRSDIHEHMLLFEEDG-FTLVV-FYRFQLREQKKQEINELLSKFKEDQERIKVMKSKR-KFNPY Aspfu1 HYLYLRPHRSLFVVNVPLRHLFGAVVVFADKSSMLLRTVNDFMTVFTEDG-FITVT-FYRFQSREKRKERQNQLLKRFDEDRKKLEEMKRRKGKIRVS Aurde31 HNLYVRAHRTLFVVNVPLSALFAAHLVFLDASSLVLEHAESAILHFDEDG-FTLVV-FYAFQVREKNLKEHAELRKKFEEDKKKVEELQKKR-AFVPY Batde5 HYLFMRPHRTLFIVNLPLRRLFRAHVVFKDDESILQSQVDQAMSLFDDDG-FVLVT-FYRFQKREAKRNELAELRRKFEEDKSKIEVLKTKR-RFKPY Botbo1 HYLYVRSHRTLFIVNLPISLFFKAHVVFLDESSLVRAHADTSVELYEEDG-FTLVT-FYTFQLREKKRQEFMDLRQKFEEDKKKIAQLKESR-RFRPY Botci1 HHIYLRQHRSLFATNLPIRSVFAAVVLLVDEKSVVQRSVDAFMTKFNEDG-FVTVVGFYRWQGREKRKKEVGELVKKFEEDRKRVEGMREKRGRFRPE Caeel RHMFLKKDNSIIVSNIPVLAIIDMSITFDKPEAVIQEMADTYVERYDEDG-WITVTAYYTFQIKKNRQEKAQELLKKFEEDRKRITQLKQAR-NFKPI Canalb1 HYIYFKKHRSLFICNLPIKKFFQGIVAFIDKASFLTEEVSQALIDFDEDG-FTLVV-FYRFQLRQRKKEEMNELLNKFKLDQEKVRMMKEKK-RFRPY Cangl HYIFARKHNCLFLVNLPLKKAFNALLKFVDEASLLKEDIHSYMSVFEEDG-FTLVV-FYRFQVRERKKQEINELLSKFKEDQAKIKVMKDKK-KFNPY Capow RFLYCKKHRALFVANLPLASLFTAYVVFSTPRGVAQAEVDEYMQKHDSDG-WVTVS-FYRFQQRDARRTQLDRLREKFEEDKQKIASMRAAR-KFRPV Catan2 HTLFFRPHRTLYVTNVPLSSLFKAYIVFKSPAALLKAAAHEAIAAYDEDG-FVLVT-FYRFQMREEKRSKLLELREKFEADKRRIDELKQAR-RFKPY Cioin ---------------------------------------------------------IYKYQVRESKRQKIAELREKFEEDKLRIQAMKEAR-KFRPF CocheC53 HYLYIKPHRSLFLANVPLRALFAAVVVFVDGKSALQSSLNAYLSQFNEDG-FVAVVDFYRFQNRERRKKAEGELKRRFEEDRKRVEGMRERRGKVRPE Coere1 HYLYFRQHRTIFMANLPIRRLFQAHIVLLEVEELLRSEVDGFMSKFEADG-FVTVV-MYRFQMRERKTDQLAELRQKFEEDKERIARMRQAR-KFRPF Conco1 HQLFVKEHRTLFLLNLPIKKFFGALVVFLEEEGLLTVFVNEYISELEEDG-FVTVS-FYRFQTRENKRDQLAQLRSKFEEDKKKIANMKAKR-QFKPY Conpu1 HYLYLRKNRTLFLVNVPIVLFFKAHVVFLDPPSLVRTHADSFMTLFEEDG-FTLVT-FYAFQKAEKQRKAIMDLKKNFEQDKARIAKLRESR-KFKPY Copci HYLYARAHRTLFLVNVPLVMFFKAYVVFLDESSLIQEHVDTYMELFEEDG-FTLVT-FYAFQKAEKQRTELMNLKKKWEEDKAKVEKLKASR-RFKPY Croqu1 -------------------------------------------------------------------------------------------------- CryneH991 HYLYCRAHRTVFVVNLPLRTVFGAHIIFLDPISVIKSFADTSMARFDEDG-FTVVV-FYKFQALDRKRQDLAELRQKFEHDKARVEELKKSR-RYKPY Crypa2 HHLYLRRHRCLFVTNVPFRAIIAAVIVLADGKSVLQQSVDAFFTLYNEDG-FVTVT-FYRFQLRERKKAEQAELIKKFEEDRKKVQAMRQKRGKFRPE Debha1 HYIFFKKHRSIFFFNLPLRKYFQGIATFVDKAALISNIVSQALVDFDEDG-FTLVV-FYRFQLRQRKKDEMNDLLKKFKLDQEKVRLMKEKK-RFRPY Dekbr2 HFLFIKKHRSLFFVNLPMKRLISGIVTFLDKSGLLASNVASSMEEFEEDG-FTIVV-FYRFQIRERKKQEVSDLLQKFKDDQERVRAMREKR-RFNPY Dicdi KYIYIKKEKTLFVTNLPVKKLFKAHIVMNDQDSLLQTKLDNIMIDYDEEG-FITVG-FYAFQHRQTKKDELDVLRQKFEEDKQRISKVTAAR-KFKPY Dmel HSIYMREHRTLFLLNVPLRTVFGAYIVFEKNSSITKLQISKYMAGYDADG-WVTVG-FYTFQIRESKMQNIVEMRKKFEEEKRKIGLLKQSR-RFKPF Enthi -------------------------------------------------------------------------------------------------- Falba HTLFIRKHSVLFVTNIPLAALFTAYVAFASAADVLSARVDKLLMSLDDDG-FVLVT-FYRFQQRQAKRDQLADLRRKFEEDKQKIERMKASR-QFRPF Fomme1 HILYAKIHRTLFLVNIPLSLFFKAFVVFLDSSSLVRTHAESAIALYDEDG-FTLVT-FYAFQKHEKKRQELIDLKKKWQEDLEKVQKLKESK-RYKPY Fusgr1 HEIRIRKNRSLFLKNIPFRSIFTAVVLLADEKSVTQKAVHAFFTSFNEDG-FVTVT-FYRFQMRERRKAEQMALLKRFQDDRRKVDAMREKRGKFRPE Galma1 HYLYARSHRTLFLVNLPLVLFFKAYVIFLDSSSLVRAFADSSIEVYEEDG-FTLVT-FYAFQKAEKQRSGLLELKRKWEEDKAKVEKLKASR-RFKPY Ganpr1 HYIYFKPHRTLFLTNVPIQRLFRAHVVFDHPEAVLFPILARTLAQHDADG-FTVVG-FYRFQFKDKRMDALAELRRKFEEDKKKVDVMKAGR-VFRPT Gloin1 HYCYFKSHSTLFISNLPIKHLFQAHIVFQNSEGLLQEEVDEYMRKFEEDG-FIMVT-FYRFQMRETKRNKLIDLRKKFEEDKEKIAKLKAAR-RFKPY Hisca1 HYLYLRPHRSIFIVNVPLRHLFGAIVVFVDRPSMLLRIVNDYMSIFGEDG-FVKVT-FYRFQMREKKKERQTELLKKFEEDKRKLEEMKRRRGKVK-- Klula1 HYMFVRKHHCLFLVNLPLKKNFQALLQFVDKQSVLKTDIHEHMALFEEDG-FTLVV-FYRFQVRERKKQEINELLAKFKQDQEKIKEMKSKR-RFNPY Lacbi2 HYIYARPHRTLFLVNIPLILLFKAHIVFLDSSSLVREHADTSIELYEEDG-FTLVT-FYAFQKAEKQRSALMDLKKKWEEDKAKVEKLKASR-RFKPY Lenti61 HVLYARSHRTLFLVNVPLTVLFKAYVVFLDASSLVRAHADSWMEAFEEDG-FTLVT-FYAFQIHEKKRKEIIDLKKKFDEDKAKIEKLKQSR-KFKPY Malgl1 HYMYIKIHRTLFVVNVPLRDLFRAHVVFLDTTSLIKKHADSAIARYSEDG-FVIVQ-FYRFQFREKKRQQFASLRAQFEADKKKIAQRKASF-RFKPL Mellp23 -------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------- Morel2 HYLYFKKHRTLFVLNIPLRELFKAYVVFLEEQELLQLKVDDYMDKFEEDG-FTLVT-FYRFQMREAKRDKLVDLRRKFEEDKLRIEALKVNR-RFKPY Mucci2 HYFYIRKHRTLFMLNLPIKKLFKAHIVFSTNDDLLQQEVDSFMMKFKDDG-FTVVV-FYRFQMREKKQNELVELRKRFEEDKAKIAQLKQTR-KFKPY Mydma HTLFIKRQYTLFVVNLPLENIFSAYILFKETESVMQLIIDTYMKDFDDEG-WTTIP-FYVFQQREIKRDQIAELRRKFEEDKKRIAMLRQQR-KFKPF Neucr2 HYLYVRRNRSLFLANVPLRALFAAVVLLADEKSVLQAAVDAFSTMFAEDG-FVTVT-FYRFQMRERKKAEQEELVKRFEEDRQKLDAMRQKRGKFVPE Orpsp11 HYIYFKKHCTIFVCNLPLKHIFKAHVVFNNEDGVLKTRVDNYMVNFTEDG-FTLVT-FYRFQMKEKKRN----------------------------- Pench1 HYLYLRPHRSLFLVNVPLRHLFGAVVIFADKPSMLLRTVNEFMTTFTEDG-FVTVS-FYRFQSREKRKERQNQLLRRFDEDKKKLAEIKARKGKIRVS Phybl2 HYMYLKKHRSLFVLNLPLRQLFGAHIVFAHTKMLLQQKVDSFMMKFKDDG-FVVVT-FYRFQLREKKQNELVELRKKFEEDKEKIAVLKQSR-KFKPF Picst3 HYIYFKKHRSIFLCNLPLKKFFQGVVTFVDKLAFLSDAVSQALVDFDEDG-FTLVV-FYRFQLRQRKKDEMNELLQKFKLDQEKVRLMREKK-RFRPY Plicr1 HYLYAHRHRTLFLVNIPFALFFKAHIVFLDSSSLVRAHADSYMELFEEDG-FTLVT-FYSFQRAEKQRKNLMELQKNWEEDKAKVEKLKESR-RFKPY Polpo KYIYYKKEKTLFVTNLPLQVLFQAHVIMKSAQSLLQIKLDDAMMEHDEDG-FILVT-FYSFQQRQQKKQELDNLRKKFEEDKQKIAKMSANR-KFKPY Pucgr2 -------------------------------------------------------------------------------------------------- Punst1 HYIYARAHRTLFLVNVPIIVLFKAHVVFLDSSSLVKAHADTYMERFEEDG-FTLVT-FYAFQLHEKKRNELLDLKRNWEADKAKIEELKASR-RFKPY Rhior3 HYIYMRKHRTLFLLNLPIRKLFKAHVVFEKSKDILQEEVDTFMIKFKDDG-FTVVV-FYRFQMRDKKMNELSELRRKFEEDKAKIAKLKQNR-KFKPY Rhoto1 THLFARLHKQLFVTGLPLKVALAAIVTFSSTPSLVIAHVDEWMRAYDDDGEWHTVSGFYSFNRAEGRKRDLANLKSRFEEDKRRLDRLRASKGRFKPY Rozal11 -----------------VKKISKLHLEF------LLKDANDFLLAYDEDG-FIKVM-FYRFQVREQKKNRLNDLREKFEKDKSRIQKMKEQR-MFKPF Sacce1 HFMFAKRHDCLFLVNLPMKKFVGALLKFVDAASILKEDIHTHMAIFEEDG-FTLVV-FYRFQVRERKKQEINQLLSKFKEDQERIKVMKAKR-KFNPY Salro HSLYIKEHRTLFVLNLP------------------------------AEA----------------------------------------HR----PF Schco3 HYIYARAHRTLFLANIPIITFFKAHVVFLDASSLVRAHADTYMDLYEEDG-FTLVT-FYAFEKAERQRKELIELKRKWEEDKEKIEKLKASR-KFRPY Schpo1 HSIFLKEDKSLYLINVPLKRAISLRVKLVEPAEVLAESVDSYMKRVTEDG-FVTVV-FYRFQLREKKKKALLDLAHKFEFDKQRIQQLKEKR-QFKPY Sorma HYLYVRRNRSLFLANVPLRALFAAVVLLADEKSVLQAAVDAFSTMFAEDG-FVTVT-FYRFQMRERKKLEQEELVKRFEEDRVKLDAMRQKRGKFVPE Sphar HYVYMRKHRTLFVTNIPIMSIFKSHVVFKSEKQLLSNEIAEAMVEFDDDG-WVTVS-LYKWQQRETRREEIADLRKNFEDDKQKIQLLRMQR-KFKPY Spipu1 HYLFIRAHRTLFVVNIPFRRLFRAHIVFVEEAAVLQRAVDTSLVAFEEDG-FVTVI-FYRFQMRETKRNQLAELRRKFEEDKLRIASLKANR-RFKPY Sporo1 -------------------------------------------------------------------------------------------------- Stehi1 HFLYIRAHRTLFIVNPPITLLFKAYVVFLDSSSLIRLHADSSIELYDEDG-FTLVT-FYAFQVHEKKRKDLMDLKANFEKDKEKVEQLRASK-KFKPY Tapde11 HHLYMRKNRTIFVANIPFKALFSAHVTFLERSELLQTAVDAYMELFNEDG-FVTIT-LYRFQRRDEQKAKMNNMRMKFEEDKKKIQELRSRRRFLA-- Thetr -------------------------------------------------------------------------------------------------- Treme1 HYIYVRPNRTIFLCNLPLRLIFQAHITFLSNISLIKVHADSALDKYDDEG-FTVVV-FYKFQRTDKRRQELAGLRKQFESDKARVEEMRNSK-RLKPY Trire2 HEVRVRRNRSLFLKNIPFRAVFTAIVLLADEKSVVQKATHAFFNVFNEDG-FVTVT-FYRFQLRERRKQEQAQLLKRFEEDKKKVSAMREKRGKFKPE Umbra1 HYMYIKKHRTLFILNLPIKRLFQAHVVLLEAKELLQSRVDSYIIKFQEDG-FVMVT-FYRFQMREQKRDQLVELRKKFEDDRKKIEQLKQTR-KFRPY Ustma22 HWIYVRKHRTLFMANLPLRDMLAAHVVFLDAASMVSTWANSVISLYQEDG-FIIVQ-FYRFQLRERKREELAGLRKRFEEDKAKVQKLKAGR-RFKPY Walse1 -------------------------------------------------------------------------------------------------- Zygro1 HYMFVKKHSCLFVVNIPLKSAFNALLKFVDEASVLKEDIAEHMSIFEEDG-FTLVV-FYRFQIRERKKREINQLLVKFKEDQERIKVMKAKK-KFNPY [Cluster2617.fasta_al_trimmed; alignment length = 82] Allma1 --------MELLFGTMRDLLPWVRDH-LLKE--RPELFMDGD-SVRPGILVLINDADWELGDLEYVLKAGDEIVFISTLHGG Ashgo11 VQVEFLGGLDVIFSTVGDLIDYIVSN-MIQKQKDVSVFLEDN-TIRPGILTLINDTDWELGEKEYVLEDGDIVSFTSTLHGG Aspfu1 ---------------------------------------------------------------------------------- Aurde31 LKVEFGGGLELLFDNVTHLVAWLKDN-LLKE--RPELFVEEQ-TVRPGILVLVNDTDWELGEGDYELKDGDEIIFISTLHGG Batde5 INLEFSGGMELLFDTLRDLIAWTASN-LLKE--RPELFIQGD-SVRPGILVLINDVDWELGELDYVLCDKDTVVFISTLHGG Botbo1 LSLHFGGGMELLFDDVRLLIDWIATN-LLQE--RKELFLEGP-SLRPGILVLINDTDWELGEEDYQLKDGDDIVFISTLHGG Botci1 IVVEFTGGLEMLFSTVGWLVNYLCDE-IMQD-SRKDMFVLDD-HVRPGILVLINDADWELGEASYELQSNDNILFVSTLHGG Caeel VTIDFSGGAEFLV-TLRDVLKFVRDN-LVTDVHRINMLLNDDASEAHGVITLINDTDTGLLEYDTVIEAGDTITFVSTLHGG Canalb1 IKVEFLGGLDIISNTVADLITYITKN-IISDPKDIPVFIEDG-TVRPGILVLINDTDWELGMEEYVIESGDVFTFTSTLHGG Cangl VRVEFLGGLDVIVNNVGDLIDYIIEN-LITNKKDVEVFIEND-SIRPGIITLINDTDWELNEKEYVIEDGDVISFTSTLHGG Capow VTLEFSGGAELLFDTIRAFLVWIRDN-LLKE--RPELFLQGD-TIRPGILVLVNDQDWELGELDYELEAKDTILFISTLHGG Catan2 --------MELLFGTIRDLLPWIRDN-LLKE--REELFLDGD-SVRPGILVLINDADWELGELDYVLQQKDEIVFISTLHGG Cioin ---------------------------------------------------------------------------------- CocheC53 MTVEFSGGLEILFANVAFLVRFLCDN-VMKD-PRKELFVLDG-TVRPGILVLINEADWELGEDEYQVQKGDHVMFVSTLHGG Coere1 LIVEFGGGLEALIKTIRDLIIHLRNF-YVKE--KPELFCTGD-KVRPGILVIINEEDWEIDKYDYELKNKDHILFISTLHGG Conco1 ITLQFSGGMELLFDTMKELIEFVKDK-HLKE--RPELFVDGD-TVRPGILVLINDADWELGELEYEVAEGDKIVFISTLHGG Conpu1 ---------------------------------------------------------------------------------- Copci IKIEFGGGLELLFSDITYLIHHMRDH-LLQE--REELFVENG-TVRPGILVLVNDTDWELGEGDYVLKDGDEVVFISTLHGG Croqu1 LKVELGGGLETLFDHIRHLISVLATR-VRPV-SSLSLFCSPG---KPGILPLINDEDWELSGMEVVLKEGDNVLFISTLHGG CryneH991 VRFEFGGGLHLLFSNMRYVVKWMKEN-LLSE--REEMFGEGD-GVRPGILVLINDADWELGELEYELRDRDEIVFISTLHGG Crypa2 ----------MLFSTIAHLIHYLCEN-VMKD-TRQELFVLDH-HIRPGILVLINDADWELGEEAYEIKSGDNILFVSTLHGG Debha1 VKVEFLGGLDVISNTMIDLIKYITAT-IISDPKDVPVFIEEG-TVRPGILVLINDTDWELGMEDYVVESGDVLTFTSTLHGG Dekbr2 VDVEFLGGLDSIFGTMRDLLAYIVQNILVDREKDLCVFMQEE-NVRPGILVLINDTDWELGELNYKLNNDDLISFTSTLHGG Dicdi VKIELSGGLELLFDPLKDLILYMRDN-LLKE--RSELFVVDD-TVRPGILVLINDADWELGGISYNVEDKDTIIFISTLHGG Dmel IILEFSAGAELLFGTIANLLKWMHAN-ILTE--RPELFLQGD-TVRPGILVLINDTDWELGELDYELQPNDNVLFISTLHGG Enthi VKIELSGGLE--YDTMRDVIHKIKE--IQTG--LAPIFTEE--SVIPGIIVLINDADWELGMLDSEVHDGDVISLISSIHGG Falba LSIEFLGGCEQLFGTIRHLLAYLRDH-HMRA--RPDLFLDVGSAVRPGIIVLINNADWELGMEDYRLQEADRVTFISTLHGG Fomme1 ------------YGDVNHLLCYLRDT-LLKE--RVELFMENE-TIRPGILVLINDSDWALGEGDYQLKEGDKIVFISTLHGG Fusgr1 IDVEFSGGLEMLFSDIAYLINYLCQN-VMDD-SRKDLFVLDS-HLRPGILVLINDADWELGEEAYEIQSGDNILFVSTLHGG Galma1 LKIEFGGGLELLFDDVDYLIHHMRDH-MLKE--RVELFMEKS-TVRPGILVLINDTDWELGEGEYELKSGDEIVFISTLHGG Ganpr1 LTLEFTGGMELLFQTVKTLLPWIRDS-LLKS--KPDMFMQGD-TVRPGVLVLINDADWELGQLSYELQEGDTIVFISTLHGG Gloin1 IKLSFSGGIELLFDTMKDLISWMKDN-LLKE--RPELFMSGD-TVRPGILVLINDSDWELGELEYEIKDGDDIVFISTLHGG Hisca1 ITVEFTGGLESIFNSVASLVHYLIEN-VMED-TRQELFVVDG-AVRPGILVLINDADWELGEEKYQIQQGDNILFVSTLHGG Klula1 VIIEFLGGLDVIVKNVGDLIQWIVDN-LIEHEGDVNVFLEND-SIRPGILTLINDTDWELGEKEYVLEDGDVVSFTSTLHGG Lacbi2 LKIEFGGGLELLFSDVTYLLHHLRDH-LLKE--REELFMENG-TVRPGILVLINDTDWELGEGEYLLKDGDEIVLISTLHGG Lenti61 LKIEFGGGLELLFSDLTYLIFWLRDN-LLKE--RAELFVENG-TVRPGVLVLVNDTDWELGEGEYQLKDGDEIVFISTLHGG Malgl1 ---------------------------------------------------------------------------------- Mellp23 LKVELGGGLETLFGDIRHLISVLATR-VNPP-TSLSLFCSPG---KPGILPLVNDEDWELSGMEAVLKDGDNVLFISTLHGG Mnele ---------------------------------------------------------------------------------- Monbr GDAARRGSCMDCFSTIKTLLAYIRDH-LLKE--RPELFMDGE-TMRPGILILVNDTDWELDGLDYQLQDKDNVVFISTLHGG Morel2 IELQFSGGMELLFDTIRDLISWTASN-LLKE--RPELFIGTDGSVRSGILVLVNGADWELGELEYELEDRDEIVFISTLHGG Mucci2 INVEFSGGMELLFENLQDLILHIRDT-MMTE--KKDLFVEKD-TVRPGILVLINNVDWELDELEYELQDKDEIVFISTLHGG Mydma VIVEFNGGAELLFENIQKLIFWIKDN-LLKE--RPELFIQDQ-TVRPGILVLVNDTDWELGELEYKLQENDIITFISTLHGG Neucr2 ITVDFSGGLEILFSNVGFLINYLCQT-LMTD-PRADLFVLGG-ELRPGILCLINDCDWELEEDAYVLQPGDNILFISTLHGG Orpsp11 ---------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------- Phybl2 INVEFSGGMELLFKTLQDLIFYLRDN-LMTE--KKDLFVDKD-TVRPGILVLINNVDWELDELEYQLEDKDEIVFISTLHGG Picst3 VKVEFLGGLDVISNTVKDLIELITKS-IIADPKDIPVFIEDD-TVRPGILVLINDTDWELGMEEYVLESGDVFTFTSTLHGG Plicr1 VKVEFSGGLELLFGDVAYLIAHLRDH-LLQE--REELFVEDG-SVRPGILVLINDTDWELGESAYVLQEGDEIVFISTLHGG Polpo VNIELSGGLEILFSPLKQLVYWMRDN-HVKE--RPELFVENG-TVRPGILVLINDTDWELGGIDAIIEDGDTVSFISTLHGG Pucgr2 LKVEFGGGLETLFSTIRHLVSLLSPQ-VRPQ-KSMSLFCSPG---KPGILPLVNDEDWELSGMHALLKHGDNVMFISTLHGG Punst1 VKVVFGGGLEQLFSNITYLIHWLKEH-LLKE--RSELFEEGG-TVRPGILVLVNDTDWELGEGDYELKDNDEIVFISTLHGG Rhior3 IHVEFSGGMELLFNRLQELIFYIRDK-MMTE--KQDLFVEKD-TVRPGILVLINNVDWELDELDYELEDKDEIVFISTLHGG Rhoto1 VTVQMSGGMELLFSDVRFLVWWLRWF-CLEDRERPELFSQGE-TVRPGILVLINSTDWELGELDYVLEDKDEIVFISTLHGG Rozal11 ---------------------------------------------------------------------------------- Sacce1 VKVEFLGGLDAIFGTVGDLIDHIVST-MINNPNDVSIFIEDD-SIRPGIITLINDTDWELGEKDYILEDGDIISFTSTLHGG Salro VSLEFSGGAELLVDTVKDLLAWIKDN-LIDE--RPELFVQGD-TVRPGILVLINGTDWELDGPEYELCEGDAFVFISTLHGG Schco3 VDVEFSGGLELLFGDVEFLIDYLARN-LLKE--RVELFVENG-SVRPGILVLINNTDWELGEGEYVLQPNDEIVFISTLHGG Schpo1 IKVELLGGLDLLFNKLGSLIDYMAQI-IEKP-SQKDLFILNG-TVRPGIIVLVNDQDWELEKEEYNLEEGDEVVFVSTLHGG Sorma ITVDFSGGLEILFSNVGFLIKYLCEK-LMTD-PRADLFVLGG-ELRPGILCLINECDWELEEDAYVLQPGDNILFISTLHGG Sphar ---------------------------------------------------------------------------------- Spipu1 IHLQFSGGMELLFNTLKDLLPWMRDN-LLSE--RAELFMQGD-TVRPGILVLINDADWELGELEYVLKDDDTIVFISTLHGG Sporo1 --------MELLFSDIKFLIWWLREF-LLEDRERPELFSQGE-TIRPGILILINSTDWELGELDYELQEGDEIVFISTLHGG Stehi1 VKIEFGGGLELLFSDITYLISWLKDN-LLQE--RAELFIENG-TVRPGILVLVNDTDWELGEGDYQLKDGDEVVFISTLHGG Tapde11 IRIALTGGLELIFQTLSHLITNLQKE-CQAE--KQELFVQNG-TVRPGILVLINDSDWELGEGEYVLQNNDEILFVSTLHGG Thetr VTVHLSGGLDVLFGLIEVLNELMGETLVAKD--RGDMLMLDG-EVRPGILVLINDADWALGENEAVVTPGDEITLISTLHGG Treme1 -QLTYRGGLHLLFSDMRYLVRWLKEN-LLSE--RPEMFGEGD-SVRPGILVLINDADWELGELEYLLKDGDEVVFISTLHGG Trire2 -----SGGLEMLFSTIAYLIHHLCEH-VMKD-SRKELFVLQD-HLRPGILVLINDADWELGEEEYELKSGDNILFVSTLHGG Umbra1 VKVEFSGGMELLFDTLKDLIFYIRDN-MMTE--KKELFVDKD-TVRPGILVLINNVDWELDELDYQLQDNDEIVFISTLHGG Ustma22 IRVEFGGGTELLLANVSFLIGHIRKN-LITE--REELFVDGD-SVRPGILVLINNGDWELGEGDYVLQDGDEVVFISTLHGG Walse1 LKIEFGGGLEILFNTVRDLIKHLADE-HINE--RKELFIEGD-TVRPGILVLINDCDWELDELDGELEQGDVVVFISTLHGG Zygro1 VKVEFLGGLDVIFDTVKDLIDYIVKN-MIRNPNDVDVFIENG-TIRPGILTLINDTDWELGGEEYELEDGDVISFTSTLHGG [Cluster2622.fasta_al_trimmed; alignment length = 203] Allma1 YPTHIPTEKVLLTVGGGLKALHDPLR-ADMVAAVGETTGRLRDQMLRSSTGRRILRERPIITSETFPPFRLELPESTLGGAYFMQKHGYVPESRVPVHFIDDAELAYVMLRYRQVHDLWHAMTG-LPPTVEGELALKAFEYAQTGLPMTALGAALGPVLLERARLYLPWAVMAGTRA-KPLMNVYYEEVLEEDLEALRQELRV Ashgo11 YEGHVPLEKALLFGISGLRSFFHPEN-GMNIVQLGEAAASLRRTMLSDATGRRILREQPNISEPDLDMDKLALPTNTLGHTFWLRKEGVTPDTRAPVTYIDDPVHAYIFKRYRQCHDFYHAITG-LPIIIEGEIAVKALEAANIGVPMAALGALLAPLRLQRERLYLPWAIETGLSA-KPLINVYWEELLEHDVDQLRAELGI Aspfu1 YPGHVPLERGALAVGSAVGSLMNPRR-ADLIAALGEATARLRDAMLSDPTGRRILRDRPRITSETLKLPYLRLPENSVGRTYWLDREGVSPDTRNSVKYIDDEECAYVMQRYRECHDFYHAVTG-LPTFVEGELALKAFEFLNTLIPMTGLS-IFAFVRLERERFHLPWAVRSGLAS-KELINVYWEEILEKDVDELRKELGI Aurde31 YEGHVPLENAFLAVGSAVMSLANPRR-GDLIATLGETTARMREHMLLSAEGRRVLRDRPRVNSDTVDMAALALPENTFGSAYWLERCGVTPDTRAAVRYIPDPELAYVMQRYRECHDFYHCITH-MPVSVEYEIALKYFEFANTGLPMTAISAIFGPLRLQKERLYVPWALRCGGSA-RPLITVYWEERWEQDIEDLKAELGI Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 NDGPIALENAFLVGGSAIASILDPRR-ADMIAVLGETTARLRDRMLESPEGRRVLRDRPLINTQTVDMEKLRLPEGTFGHTYWLDRCGVTPDTRDRVMYITDPELAYVMQRYRECHDFYHAICG-LPVDVFSELAIKYFEFANMGLPVSALSAAFGPLRLKRERLFVPWALRCGSSS-KSLITVYWEERWETNTEELKKELGI Botci1 YPGHVPLERGGLAVGSAVMAFFNPYR-ADLIAACGEATARLRDAMLSSPTGRRILRDRPRISSKTLSMPRLRLPPNTVGRCYWLDREGVSPDTRDSVKYIDDEECAYVMQRYRECHDFYHAITG-LPIVREGEVALKAFEFANTLLPMTGLS-MFAVMSLERRRFYAPWAFANGLKA-EEVINVYWEEQLERSVEELREELGI Caeel YASHVPLSRMLLGIGSAVTAISDPKR-GDMVAAMGETTANIRKRMESDVVGKRLLLEKPRISNGTIDRKWLRLPDGTLGKLYFLDRLNTSPDARPTVKYIDNLEHLYVMQRYRETHDFTHIALE-QKTNMLGEVTVKYFEGIQYGLPMCVTGGIFGGARLNRQELNLPWVVEQATNA-RFFMAFDWENHFEKQLSEVQKELNI Canalb1 YPGHVPLEKVLMFLGSSMGAFFHPEE-NKYIVALGESTANLRHKMLSDPVGRTILREKPRMTSDSLNLTYLRLPDNTIGKNYWLDKEHVSPDTRVAVRYIDNEELAYIYQRYRECHDFYHAITG-LPIIIEGEIAVKVFEFANIGIPMSGLGALFAPLRLQRQRLYYPWAIKNGLFS-KPLINVYWEKILEKDVDEFRQEMGI Cangl YEGHVPLEKMLLFAISGIRAFFHPEN-GINIVQLGEATANLKQTMLADETGRRILRDQPNVRTDILDMDKLSLPKNTFGYTFWLEKEKVSPDTRAPVTYIDDPIHAFVFKRYRQCHDFYHALND-LPIIIEGEIIVKALESANMGIPMATLGWMLAPLRLQRDRLYLPWAIKTGLTC-KPLINVYWEELLEKDVEELRQELGI Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 YPSHIPTEKAFLTVACSLKAIHDPLR-ADMVAAVGETLGRMRLQLLATPTGRRILRDRPLISSQTLSPTYLSLSPSTFGGAYFMHPHGYLPESRAPVRFVDDGELAYIMLRYRQVHDFWHALTG-LPPTVEGELALKVFEYVQTGLPMTLLAGLVAPVQLQQKRLLVPWAIRAGIKA-KPLMGVYYEEWLERDLNEMRRELRI Cioin YPNHIPISRILLAGSSAVAALRNPYR-DDMVAVCSETTAHMRGRMLDDETGRRILNEQPRVNSSTVDLKLLRLPESTLGRQYMLNKYNITPDSRRDVKFVDDPELAFVLQRYRETHDFNHLLLG-QRTNLRGEVAVKWFEAIQTFLPMCWMAAVGGTTRLRRLRLDLPWIIPTAKSC-QFFMNIYFEERLDQDIDDLRDEMKI CocheC53 YQGHIPLERLGLALGSGIGSFLDPRR-GDLIASFGEATAKLRDRMLLHPTGRRILRDRPRLTSTSLDIPRLRLAPNTLGYAYWLDREGVSPDTRAPVQFIDDEECAYVMQRYRECHDFYHALVG-LPVFREGEVALKAFEFANTGLPMTGLA-VFSAFTLEWRRFYGPWAARNGALS-GDVINVYWEEELETDIDELRTRLGI Coere1 YPTHRPTQKAFIAAGSALMGFGDPME-GAHIAALGDSTSKMREQMINDPTGRRILKERPEISFTPEKWEALAMPEGSFGRSYQMKRNGISWATRPPVHFVDSEEDAYMLLRYRQCHDFYHVILD-MDISVVEELAIKVFEWRQTGLPVGLIASMFGPLRLERSRFYLPWALQCGSQA-KPIISIYWEEMMERSIDEVRKEMGV Conco1 YEGHIPLEKSTVAVKAAFGALLDPTK-QELVAALGETTSYMRDRMLQDREGRKILRERPIVSTSTIDLEYLSLPKNTFGYNYFLDSNKIGPDGRTPVHYVDDEELAYVINRYRQVHDFFHTLFD-LNISVQEEISVKWFEMVHFQLPMNTLSALFGPLRLERTELSVPWALTVGNQA-KFLLSVPYEQLFEKDLNELREELNV Conpu1 YPGHIPLENGILAVGSAVMAFLDPRR-ADMVAALGETTAKLRDAMLESPEGRRILRDRPRIHSTTINMDRLRLPNGTWGRAYWLDSCRVTPDSRDPVHYISDPELAYVMQRYRETHDFYHALFG-LRVNALPELAVKAFEFTNLGFPMTAM-ALGAAVKLQREKLYIPWAVKCGSSS-RNLLTVYWEKRWEQDLSELHKELGV Copci YEGHIPLENALLTAGAAYMSITDPRR-GDMVAALGETTAWLRDQMLASPEGRQILKDRPRITSSTVDMDKLAMPEGTFGRAYWLERCGVTPDTREPVHYIDDPELAYVMQRYRECHDFYHCICN-MPVNVESELAVKYFEFANLGLPMAGLAALFGPLRLKRNWLAVPWALKCGSSA-RSLITVYWEKRWEEQVEDMKKEFGI Croqu1 YEHHVPLEQTFLAIGSALASLNNPYR-GDMVAVLSETTARLRDQMLEDESGRNLLRNRPRIRSSDINLPYLKLSSGTFGRSYWLDRCNVSPDTREPVRYIDSPELAYVMQRYRECHDFYHVIAGEFPVSVSGEVIVKWFELANMGLPVAALSAIFGPLRLRRSRLFVPWALKCGSSS-KPLICIEWENHWEKDLKLLKQEIGI CryneH991 YPGHIPLQNALLAVGSGVVGVLDVTR-GDLIASLSESTAALHEKMKIMPEGRQIMKDRPEITNKTI--EKLKLKRGTLGREYWLGDGGLEPESRAPVQYIDSPVLAYTMLRYRQTHDLYHTLFS-LPPTLPHELSLKVLELSNMSLPVALLSSVFGPLRLRKETWWVPWALRTGREG-RSLVTVYWEKRWEQGIGELRRELGV Crypa2 YPGHVPLERAGLAIGSGIMSFLDPYR-GDLIAAFAEATSRLRDAMLRSPTGRRILRDRPRLTATSLNLPHLRLGPNTVGRTYWLDREGVSPDTRSAVRYIDDEECAYVMQRYRECHDFYHALTG-LPIVREGEVALKAFEWANTGLPMTGLS-MFAALTLERRRFYLPWALRNGWRS-EEVINVYWEEELETDVDELRARLGV Debha1 YPGHVPLEKLLMIAGSSLGAYLHPER-NEFIVALGESTAKLQTQMLSDPVGRQILRERPRITSTSLDLDKLRLPDNTIGKTYWLDREGVSPDTRVPVKYIDDEELAYIYQRYRECHDFYHSITG-LPIIIEGEIAVKILEFMNIGIPMSGLGALFAPLRLQKERLYYPWGFKSGLNS-KPLINVYWENILEEDINEFRHKMGI Dekbr2 YPNHVPLEKAAMFLFSSIGALLHPEK-NQYIVALGESTAWLRKQMLEDETGREILKNRPYITSETLHMDKLKYPENSFGKVYWLLRENVSPDTRVNVKFIDDEELAFVFQRYRQCHDFYHALTG-LPIAREGEIAVKFFEFLNIGIPFAGMGALFAPLNLQRERLYYPWAIDTAAHCKKNLINVYWEKIMDKDVDELRAELGI Dicdi -KKYFTTQKGLLTIGSAFVAFINPGR-GDMVATLGEMTGSMKQKMMLDPIGRQLLKEKPRIKESTYPLN-IHLPSTTFGGAYWMKEHGYSPDERTEVTLIQDEDDAYVMQRYREVHDFWHVLAG-VRPDFQGEVAIKWFEFLQTGLPMNAIGSIIGPLRCERNELMIPWAIKSSKSC-VYLMNVKYEDHWEDDLNEFRAKLNF Dmel LKERIEIQRLFLGAGSSIAALLNPRR-HDMIACLGETTGTILDTMQASEEGQRIMADKPRIHTSTIDFKYLELPPDTFGAAYFLKDNQVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLD-MPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLQRRAYYLPWALENGKRT-KPLMPVYWEKRWEQNIHELRSELGI Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 YEGHTPLENAFLAVGSGIVLLTDPAR-ADMVAALGETTACLREHMLESAEGRRILKARPRINTRTVDMASLALPENTLGRTYWLERCNVTPDSREPVHYIDDPELAYVMQRYRECHDLYHAAIG-LPVDGLSELAVKAFEFANLGLPMAALSATLGPLRLRKERYYLPWALRCGGSA-RSMITVYWEERWTQDIGELRRELGL Fusgr1 ------------------MSFFNPYR-HDLIAATGEATARLRDAMLADPTGRRILRARPRISSKTLSLDALRMPENSVGRAYWLDREGVSPDTRASVRYIDNEECAYVMQRYRECHDFYHALTG-LPIVREGEVALKAFEFANTLLPMTGLS-IFAAATMERQRFYLPWALKNGARS-KEIINVFWEERLEEDVNNVRKELGI Galma1 YDGHIPLENAFLAVGSAFMSLADPRR-GDMIAALGETTARLRDRMLENPEGRRVLKERPRVNSSTIDMNKLVYPEGSFGREYWLERCGVTPDTREPVHYIDDPELAYVMQRYRECHDFYHCICN-LPVNVESELALKYFEFANLGLPMTAISALFGPLRLKRARLYVPWALKCGGSA-QSLITVYWEARWEQNIEDMKKEFGI Ganpr1 YQSHIPSQKLVIAVGSAFTALAVPTR-ADMVAALGETT-RIRDKMMADAVGRRILREKPVVDSATVDLDALRLPNGTFGREYWLDAEGVGPDSREPVKYVDDAVLAYVMQRYRQVHDFWHVVTG-MSVSVEAELAVKWWEFAHHGMPVALLSGVFGPLRLQRERLYVPWALRNAGRG-KYPMNVYYEEKWEMPLEELRKELGV Gloin1 -----------------------------MIATLGETTGEMRDNMLRDKTGRRILRERPRIHSSTIDIPYLRLPLGTFGKEYFLDEQKVTPDTRVKVQYIYDDELAYVMQRYRECHDFFHTLTN-LPTNVEGELALKWFELVQTGLPMTLLSSIFGPIRLEKERLYVPWALQCGSQC-KFLLNVYYEECWDKNIEEMRKELGI Hisca1 YPGHVPLERGALAVGSAIGSLINPRR-ADLIAALGEATARLRDVMLSDPTGRRILRNKPSINSKTLSVEYLRLSPNTVGRTYWLDREGVGPDTRAKVQYIDDKECAYVMQRYRECHDFYHAITG-LPVVAEGEIALKTFEFANTLLPMTGLS-MFAVMRLEKERFHLPWAVRNGLAS-KAVINVYWEEQLERDVDELRKELGI Klula1 YEGHVPLERMMLFGISGLKSYFHPEN-GENIVQLGEATASLKRTMLLDKTGRRILQDRPNITSESLDMERLSMDKNSVGYTYWLMKEGVSPDTRAPVTYIDDPVHAFIFKRYRQCHDFYHAIND-LPIIIEGEIAVKAFEASNIGVPMAALGALLAPLRLQKERLYLPWAVKAGLNC-KPLINVYWEEILDKDIDELRRELNV Lacbi2 YEGHIPLENAVLAVGSAFMSLADPRR-GDMVAALGETTASLRDRMLDSIEGRRVLMQRPRVNSSTIDLNKLAYPEGTFGRAYWLERCGVTPDTREPVHYIDDPELAYVMQRYRECHDFYHCICN-LPVNVESELALKYFEFANLGLPMTLLSALVGPVRLKRQRLFVPWALKCGGSS-RSLITVYWEERWGQNVADMKTEFGI Lenti61 YEGHIPLEHGFLTLGSAFMALVNPRR-ADMVAALGDLTSRLRDRMLESPEGRQILKERPRINTHTVDMNKLALPEGTFGNAYWLERCGVTPDTREPVHYVDDPELAYVMQRYRECHDFYHCILG-MPVNVVAELAVKFFEFANLGIPMTGMAAAFGHLPLKREKLYVPWAVKCGSSA-QSLITVYWEKRWEQNIDEMKRELGI Malgl1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 YEHHVPLEQTFLAVGSAIASLNDPHR-GDMVAVLSETTAKLRDQMLESESGRRILRTRPRIRSGDIDLNRLKLEPGSFGRTYWLERCHVSPDTRETVRYIDSPELAYVMQRYRECHDFYHVISGGFPVSVSGEIIVKWFELANMGLPVAALSALFGPLRLRRARLYVPWALKCGSSA-RSLISVEWETHWEMQIDELRETLGI Mnele ---MIKLQRALLVAGSAVGALANPLR-GDLVATLGETTGTMRDKMRMNKT--EILKDRPRVTGDTMDTEYLSLPANTFGHHYFMSSNKLSAQ-RAETKFVEDEELAYVMTRYRENHDFLHTLTG-LGVTVPEEICLKWYEMVQTELPMCALSALFGPIPLEKRLLQIPWGLACGRAS-AFFMNIYFERELETDINLMRKRYKI Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 YDGHIPIQRTILAVGSAFTALANPLR-GDMVAALGETTSRIRDQMLQDPEGRRILRERPVITSETMQLDTLRLPDGTFGREYFLDDQQVSPDTREPVHFVDSEELAYVMQRYRETHDFYHTLTG-LPVTVDGEIALKWFEMAQTGLPMTMLSSFFGPLRLERERLYVPWALENGSTS-KLLMNVRWEEWMEKPVEDVQRELGV Mucci2 ----------------------------------------MRDQMLASDVGRRILRERPIINTKTLDFDTLKCAPGTFGQTYWLEAEGVTPDTRCDVKYVDDEELAYVIKRYREIHDFFHTLTG-LGVTVEEEIALKWFEWAQTGLPMTMLASVFGPLRMERKRLYVPWALQCGASC-TPLMNVYFEEHFHTPLDEFRKQLGI Mydma YDLHIQTQKIMLTVGSAFAALYNPYR-GDMVAALGETTGKLHLQMLNDDTGYRILKEKPIIDSHILDIKKLLYPKNTLGYCYFMHSQNLSADDRSPVRFVDNTELAYVMKRYRQIHDFCHVILG-FSVDVSAEIVVKWFECFHFNLPMAALSSVFGPLALEQKELYIPWAVFTGMSA-KPFLNVYFEKNLERDIFELRNELHV Neucr2 YPGHVPLERFGLFVGSGLISLADPLR-GDLIASFAEATARLRDAMLSHPTGRRILRQRPRITSQSLNIPYLRLPPNTVGRTYWLDREGVSPDTRSAVRYIDDEECAYVMQRYRECHDFYHALTG-LPIVREGEVALKAFEFANTLLPMTGFS-VFAAFTMEQKRFYFPWAVKNGLRA-KEVINVFWEEELERDVNDLRRELGV Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YPGHVPLERGALALGSAIGSLINPRR-ADLIAALGEATARLRDAMLSDPTGRRILRDRPRITSETLNMTHLRLPENSVGRTYWLDREGVSPDTRDNVQYIDNEECAYVMQRYRECHDFYHAVTG-LPIFVEGELALKALEFLNTLLPMTGLS-LFAFVRMEKERFHLPWAIRSGLGS-KELINVYWEEVLEKDVDELRAELNI Phybl2 YETHVPVEKVVLAVGSAFTALINPLR-GDMVATLGETTGSMRDQMLSSSSGRRILRERPSIHTSTIDFDKLRCAPNTFGAAYWLDAEGVTPDTRSPVRFVDDEELAYVMKRYREIHDFFHTLTG-LGVTVEEEIALKWFEWAQTGLPMTMLSSLVGPLRLEKQRLYVPWALQTGASA-TPLMTVYFEDHFDVPLDALRAQLGI Picst3 YPGHVPLEKMLMFLGSSVGAYTHPER-NEFIVALGESTARLQHQMLSDPVGRQILRERPRMTSTSLDLEHLRLPDNTIGKTYWLDKEGVSPDTRVEVKYIDNEELAYIYQRYRECHDFYHAITG-LPIIIEGEISVKVFEYMNIGIPMSGLGALFAPLRLQKERLYYPWAFKSGLNS-KPLINVYWENILEEDIDEFRKTMGI Plicr1 YEGHIPLENAFLAAGSAFMSLANPRR-GDMVAALGETTARLRDIMLESPEGRKILKERPRVNSRTIDMDKLAYPEGTFGRAYWLERCGVTPDTREPVHYISDPELAYVMQRYRECHDFYHCICN-LPVNVESELALKFFEFANLGLPMAAFSAAFGHLRLKRQRLFVPWALKCGGSS-RSMITVYWEDRWGQNVEEMKQELGI Polpo FNNYVTTQKVLLGVGSSIVAMINPGR-GDMIATLGEITGTLKKKMMEDEVGRDLLARKPRIRSETFPPN-LHLPPTTFGGAYFMNIHGYSADERTHVRMIEDDDEAYIMQRYREVHDFWHVLAG-VDTTVQGELAVKWLELLQTGLPMCAISAAVGPLRLEQKVLMIPWAVRCARNS-KFLMNVRYEDHWETPIEDLRKLLNF Pucgr2 YANHVSLQRTFLAIGSALASLNNPYR-ADMIAVLSETTGRLRDQMLADEAGRRLLRDRPRINTSTVDLISLDLPQGTFGKEYWLRWCNVSPDTREPVRFIDSPELAYVMQRYRECHDFYHVISGPFPVNISGEIVVKWVELANMGLPVAGLSAIFGPLRLKRRELYVPWALRMGSSC-KPLICVEWEKHWETPIDQLKRSLGI Punst1 YPGHIPLENAFLAVGSAVMSLADPYR-GDMIAALGETTAKLLDTMLASPEGRRIMKERPRINTKTVDMAYLSLPKGTFGKSYWLERCGVSPDTREPVHYISDPEQAYVMQRYRETHDFYHTLTN-MPVSVTYELAVKWFEFANLGLPMALLGGVAGPLRLQRERLYVPWALKCGSSA-RCLLTVYWEERWEQPLEEMKKELGV Rhior3 YDTHIPIERTVLTVGSAIAALKNPLR-GDMVATLGETTGKMRDQMLQSKDGRRILRERPVISTTSIDFDTLKCAPNTFGYAYWLESEGVTPDTRSNVQFVDDEELAYVMNRYRQIHDFFHTLTG-LGVTVEEEIALKWFEWVQTGLPMTMLASLFGPLRLERRRLYVPWAVQCGASC-KPLMTIYFEHHFYTPLDEFRRNLGI Rhoto1 YHGQVEIERGLLVLGSAVMGLVDTHR-HDMIAVLSE-TSRLHNAMRKSPSGRAILRDRPRITSTSISLPELALPPGTFGRAYWLTRNRVTPDTRDPVRYIPDPDLAYVMQRYRESHDFYHVLLG-FGVSLPAELVVKWFELANFGLPVAALSGMFGPLRMERDRLYGTWALRAGGKA-DCLISVYWEKEWETPIEELRARYGV Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 YNGHVPLEKLLLFAISGWNSFFHPED-GYNIVQLGEATANLKQTMLSDSSGRRILKEQPNITTEILHMDKLALPHNTFGYVYWLKRENVSPDTRAPVKFIDDPMHAYIFKRYRQCHDFYHAITN-MPIIIEGEITIKALEGANLGVPMAILGGILAPLRLQRKRLYLPWAVRTGLSC-KPLINVYWEEMLEKDVTALRKELKI Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 YPEFIKLENAFLAVGSGLVALANPRR-GDMVATLAETTARLRDIMLKSEEGRQILKERPRINTNTVDMEALDMPEGSFGKSYWLHRCGVTPDTRAPVQYIEDPELAYVMQRYRECHDFYHAIVN-MPVSVEYEVAVKAFEFANLGIPMTGLGAALGPLRTRRRRLFMPWALRCGSSA-RSLITVYWEKRWDQNIEDMKREFGI Schpo1 YPGHVPLQRIFLVAGSAIMGLKAPWRGGDMISVLGDASGRLLNKMLVDKTGREILKDKPRMTSKSLNLPFLRLPPNTLGKIYWIDKEHVGPDTRSPTRFVDDPEEAYVMQRYRESHDFYHAICN-MPTNIEGELAIKWLEFVNMGLPVGALSALFGPLRLQASRFYIPWSIRNGLNA-KTLINVYWEKELTNDIEDVRRRIRI Sorma YPGHVPLERFGLFVGSGLISLADPRR-GDLIASFAEATARLRDAMLSHPTGRRILRLRPRITSQSLNIPYLRLPPNTVGRTYWLDREGVSPDTRSAVRYIDDEECAYVMQRYRECHDFYHALTG-LPIVREGEVALKAFEFANTLLPMTGFS-VFAAFTMEQKRFYLPWAVKNGLKA-KEVINVFWEEELERDVDDLRRELGV Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 HGTYGPAERTWIAVSSAFGAMADPTR-QETVAYLGEATGRARDKMLVHPVGRRILRERPVINTTTLDLDRLRLPDGTFGREYFLDTEHVSPDTRVPVKFIGNTELAYVMQRYREVHDFWHTLTG-LPTTIEAEIGLKWLEFVQSGFPVAMLSAFVGPLRLEREVLYVPWAVQCGSSC-QFLLNIYYEEHMHRPLDELRKELGF Sporo1 YPGHVEIQRGLLAVGSAFMGLVDTSR-HDMIAVLGETTSHLRSRMKATESGRSLLRERPRITERSINLERLAMGENTFGRKYWLKRNKVTPDTRDPVRYIDDPELAYLMQRYRESHDFYHVLLG-FGVSLQAELVVKWFELANFNLPVAALSSIFGPLRIERRRLYGPWALRAGGKA-ECLIGVEWEKELETDIDELRKKFGV Stehi1 YPGHIPLENAFLAVGSAVVSLTNPRR-GDMVATLGETTARLRDIMLESAEGRRILKECPRVTSTTVDMNALALPEGTFGHTYWLERCGVTPDTRAPVHYISDPELAYVMQRYRECHDFYHSLLN-LPVSVEYEIALKVFEFTNLGLPMTLLSTA-AAVRLKRKRLYVPWALRCGSSA-KSLITVYWEEKWAMDVGELRRELGV Tapde11 YPGHVPLERIMLATGSAIQSLVDPRR-GDMIAALSEATARLRDQMLAHPTGRQILKDRPRITSQTLSLEYLRLPQNSVGYTYWLDREGVTPDTRDATRYIDDEECAYVMQRYREAHDFYHAITG-LPVIVEGEIALKWFEWTNMGLPVAGLSALFGPLRLQRARLWIPWALSEGQRS-TCMLNVYWEKELLSDCDELRAKLGF Thetr -------QRVVLAAGAAVGAFLDPTR-ADLVSALGETTGTMRAQMARDETGARILAERPMIDSATAAEAAAATPESSFAAAYFLATHGFSPDERPAVRFVDDDELAYVMLRYRQVHDFWHVLYG-VKPDVEGEVMLKWIEAGETGLPMNVLSALAGPFITQQPQG-------------TAHVCVL------------------ Treme1 YPGHVPLQNALLAVGSGIMGVMDTSR-GDLIATLSESTARLHNTMVSHAEGRQIMRDRPLVSSSTVNLEALKLRRGTLGREYWLEKQNVTPDTREVVRYIDSPTLAYTMTRYRQTHDLYHTLFS-LPTTLPHELTLKVVELSNMSLPVAALSSLFGPLRLRREVWWVPWALRTGANG-RSLVSVYWEKRWEQGVGDLRRELGV Trire2 YPGHVPLEQAGMALGSGIMSLLNPYR-ADLIATLGETTARLRDAMLAHPTGRRILRQRPRISSKTMSLPALRLPPNSVGRAYWLDREGVSPDTRSPVRYIDDEECAYVMQRYRECHDFYHALTG-LPTVREGEVALKAFEFANTLLPMTGLS-MLAVATLERRRFYMPWAVKNGVRS-QDIINVYWEEQLERDVDDLRRELGI Umbra1 YETHIPIERVILAAGSAVTALLDPYR-GDMIATLGETTGSIRDQMLQDRTGRRILRERPVINSKSLDLDRLRLPSDTFGREYWLDKEGVTPDTRAAVQFVDDEELAYVMKRYRECHDFFHTLTG-LGVTVEEELALKWFEWVQTGLPMTMLSSLFGHLRLERSRLYVPWAIQCGVSS-KPLMNVYFEELLDKPLTSVRKELGI Ustma22 EVDHIPTGRVLLTAGSALGLLNNPSR-GDLLSMLTQVSSHLLESMRSTESGRRLLIERPSVNSETVDVDYLALERGKFGREWWLKDNGVGPDGRAEADYMTTLEHKYLIQRYRESHDFYHLLLR-MPVTQLGETVVKYFELAQMNMPVAGFAAAGGTLRISLSALLIPWAMQVGSSS-VPLISIEWERCWERDIEEMRREFRI Walse1 YPGHWPVENLFLAAGSAVVSLVDVYR-HDMLATLTETSTQMRQGMLSSDNGRRILAERPRISTKSVDLDALRLPKGTLGREYWLERCGVTPDTRDPVHYIDDEELAYIVQRYRESHDLYHLLLG-QRVDILSELIIKWFEFSHFKLPVAGLSSAFGPLRLQRQDLSGPWAIRQGNRC-APLMGIYWENEWSTNLAELRQRMNL Zygro1 YEGHVPLERMLLFAISGLKSFFHPED-GNNIVKLGESSASLKQCMLGDETGRRILREQPNITSDTLDMDRLKMDKNSLGYTYWLITEGVSPDTRAPVKYIDDPLQAFIFKRYRQCHDFYHAING-LPIIIEGEIAIKALEAANMGIPMAALGALLAPLRLQKERLYLPWAIRTGLSC-KPLINVYWEELLEKDVNELRKELGI [Cluster2624.fasta_al_trimmed; alignment length = 476] Allma1 --------------------------------------------------------------------------------------------------MQQLVFHY-PNLAVMEGSVEDLLADGDVIPTSRVVLTTGTFLGGEIHIGMETYP-AGRMGDGLSDTLA-GFQLGRLKTGTPARLSRKTIDWSQEGENPPTPFSYLH-QIL-CYQTHTTSSTHDLIRANLHRTFHIRE-TVKGPRYCPSIEAKILRFSTKERHVIWLEPEGLTTDSIYPNGISNSLPVDLQLQMLRTIPGLENVEMLRPAYGVEYDHIDP-RELRETLETRRVRGLFLAGQINGTTGYEEAAGQGLVAGANAALLGRGDAYIGVLVDDLTSKGVTEPYRVFTSRSEYRLLLRSDNADARLTRRGGLVSRA-RSAWTVLARVETEAMYYQKEKHRAIPEDIDYLSLRPTNVHQLKSMEGITPAAIMTVLK Ashgo11 SGVVVIGGGHAGCEASSAAARAGGKATLVTDKIGTCSCNPSMGGIGKGTLLREVDALDGLAPRVTDLAGLQFKVLNRSRGAAVWGPRAQIDRKIYMREMQRVMTNY-PGLTLLEGSVDDLLQDQRLLRASRVVLTTGTFLGAEIHIGLQSFP-AGRLGEGISKTML-DFMMGRLKTGTPARLDKNSIDYTEFGDEPPHPMSYLN-QEV-CFGTHTTKELHAYVVSNLHQSIHIKE-TVKGPRYCPSLEAKVLRFPHKDSHRIWLEPEGWDSEVIYPNGISNSMPEDVQHRMLQMIPGLANVKMLYPAYGVEYDYIDP-RELKQTLETKRVDGLYLAGQINGTTGYEEACAQGIVAGANAGLIGRPDAYVGVLIDDLITKGVEEPYRMFTTRSEFRLTVRADNADMRLTDLGGVVGDE-RSAWEMYHKLDAEGRYYQADENIRLPDNIDYSTVRPQTLGQARRIQGITPVAMFELYK Aspfu1 YDVVVIGGGHAGSEASAAAARSGARTALVTSNIGVCSCNPSFGGIGKGTMIREIDAMDGVAGRIIDKAGIMFRILNRSKGPAVWGPRAQIDRDLYKRYMQEELLAT-EGLSIVEGKVADILESGEVIPTGRVVITTGTFLGGEIHIGLEAYP-SGRMGEGLSKSLA-GFQLGRLKTGTPPRLDMKTIDFAQRGDSPPQPFSYLNGQLT-CWMTHTNEASHEIVRANLDKSIHIRE-TVRGPRYCPSLESKIIRFTDKKQHQIWLEPEGFANEVIYPNGISMTIPADAQYALLRTVRGLENVRMLQPGYGVEYDYIDP-RNLRPTLETKLISGLYLAGQINGTTGYEEAAGQGIIAGTNAGLLTRSDGFIGIMIDDLITKGVSEPYRMFTARSEYRISTRSDNADLRLTRMAGVVSDK-RSALDLLTRVSIEGRYFLQDESLILPPDLDYSKVRPVSVGMARRIEGVTPAGALRLLM Aurde31 YNVLVIGAGHAGCEAAAAAARAGARTALLTSATGALSCNPAIGGVGKGTLVREVDALDGLIGKVADKAGIHFTMLNRSKGPAVFGPRAQVDRVLYAHHMQEALFNY-PNLDVREAAVHDILESGETVPADAVVVCTGTFLAGVIHIGNESRP-AGRLGDGLSATLF-QLRLGRLKTGTPARIYKRSIDFDHDPDARPEPFSFLH-QVP-TYQTHTTQATHDIVRENIGSSLYIKE-SINGPRYCPSLEAKIMRFSDKASHTVWLEPEGYESELIYPNGLSNSLPVDLQEAFIRTIPGLERAEMARPAYGVEYDFVDP-RELGPTLEVKNIRGLYLAGQINGTTGYEEAAAQGVLAGANAGLLGRADGYVGVMVDDLIHRGAEEPYRMFTSRAEFRMTLRADNADLRLTPKGGIISDE-RSALELLERVAVEVRYFLSDEDLRLPEDTDWHAVRPASIGAARRMEGMTPAGAVALLR Batde5 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 YDVCVIGGGHAGCEAAAAAARTGARTLLLTDTVGEMSCNPSFGGVGKGTLVREVDALDGVCGRIADKAGIQFHVLNRSKGPAVWGPRAQIDRKLYKTHMQDTLFNY-PNLDVRAASVFDLLDTGETIKCSSVVLCTGTFLSGEIHLGLEAYP-AGRLNEGLSASLA-GFKLSRLKTGTPARLRKDSINWDQDGDIRPVGFSYLT-QVA-CYQTRTTPDTHKIIRDNLHLSIHIRE-TVKGPRYCPSIESKVIRFASKDSHVVWLEPEGYDSDLIYPNGLSCTLPPDIQERLLRSIPGLENVEMVRPGYGVEYDCIDA-RELKTTLETRRIKGLFLAGQINGTTGYEEAAAQGVLAGANAGLLTRADAFIGVMVDDLCRVGAQEPYRMFTSRSEYRMSIRADNADSRLTELGGVVTPT-RSVFDLLSRVETEARYFLSTENLMLPADLDYSSVRPESIGAVKRMEGMTPTSIVALMK Botci1 YDVVVIGGGHAGAEACAGSARSGARTALITENIGVCSCNPSFGGIGKGTMLREVDALDGVAGRIIDKAGVQFKVLNRKKGPAVWGPRAQIDRDLYKKHMREELEAY-PNLSIVTGSVADILESGEIIPTKQVVITTGTFLGGEIHIGLECYP-AGRMGEGLSKSLA-GFTLGRLKTGTPPRLAKGSIDFKQPGDQPPTPFSYLN-QLL-CHATYTNEASHAVVRANLDKSIHIRE-TVKGPRYCPSLESKVIRFSDKDRHIVWLEPEGFDSDVIYPNGISMTIPAEAQEQLLKTIPGLENVTMTAPGYGVEYDYVDP-RSLKATLETKAIQGLYLAGQINGTTGYEEAAAQGIIAGINAGLLSRSDGYIGIMIDDLITKGVSEPYRMFTSRSEYRMSARADNADLRLTEKGGVVGEK-RNALDILDRVGIEAVYFQKDEMLKLPVDLDYDSIRPESVGQARRIEGMTPSGCLRLLA Caeel VDVIVIGGGHAGCESAAAAARCGSNTVLVTNTIGEMSCNPSFGGIGKGHLIREVDALDGLCARICDKSAITYQALNRAQGPAVLGLRAQIDRKLYKTQMQNEINST-KRLEILEGEVAELMMNETVIRTKCVVITTGTFLRAQIYQGMKTWP-AGRIGERLSESFH-GFELGRLRTGTPPRLMKDSINFSVAPDRTPIPFSFLT-QLP-TYLGHTNDEVCRIGNENMHENYQVAS-ETTSPRYCPSLESKLLRFP-KLHHRLFLEHEGLDSPHIYPQGMSLTFKPEVQTQLLRAIPGLENVEIFQPGYGVQYDFVNP-KQLKRTLETRKVEGMFLAGQINGTTGYEEAAAQGVVAGINASAVSRTEGYIGVLIDDLTSLGTNEPYRMLTSRAEFRLYLRPDNADIRLTELGNAISDN-RSAFDLIERLKIEGRYIDRESATAIPDNTDFSTMRPRNLAAATRISGITPEAIVVLMR Canalb1 HPVIVIGGGHAGCEAATGSARSQTPTTLITNKIGTASCNPSMGGVGKGTLLREVDALDGVSARITDKAGIHFRILNASRGAAVHGPRAQIDRKIYLEEMQKEILNY-PNLKVLEAQVEDILSDGRVLKSEKVVVTTGTFLGGEIHIGLKCFP-SGRMGEGLSKTLA-GFRLGRLKTGTPPRLSSRTINFKQPSDFPPQPMSYMN-QLMKCYQTKTNPEFHKIIADNLDKSIHIRE-TVKGPRYCPSIESKVIKFPHKDYHYVWLEPEGLDSDLIYPNGISCTMPEEIQEKLVRLMPGCENVTMTQPGYGVEYDFIDP-RELKSTLETKLVNGLYLAGQINGTTGYEEAAAQGCIAGINAGLLKRPDGLVAILIDDLITKGVEEPYRMFTSRSEFRFSIRSDNADDRLTQKGGVVSEE-RSGWKLLNKIDVVSDYFESLDMYKLPQNFTYDNSQPTTIGQAQSLQGITPTAINELKK Cangl HDVVVIGGGHAGCEAATAAARSGARTVLVTDKIGTCSCNPSIGGVGKGTLIKEVDALDGVAGRVTDKAGIHFKMLNQSKGAAVWGPRAQIDRNLYLKEMQSILSNY-PNLQLQEAKVKDLLEDSTIMRTRKVVITTGTFLSAEIHIGMKCIP-AGRIGEGLSKTLI-GFKLGRLKTGTPARLDGKTIDFSQYPDEVPHPMSFLN-QLL-CYGTTTTPELHEYLRQNLDKSLHIRE-TIKGPRYCPSIEAKILRFADKQSHKIWLESEGLDTDVIYPNGISNSMPEDVQLKMMRMVPGLENVRIIHPAYGVEYDYIEP-TQLNHNLETKLVNGLYLAGQINGTTGYEEACAQGVIAGANAGLLSRSDAYIGVLIDDLVTNGVVEPYRMFTSRSEFRITTRAENADFRLTPIGGIVDDT-RTAWEVFLKLDVEGKYFQADEQMLLPKKFDYSNIQPNTIGQARRIQGVTAAALFELYK Capow YDVIVVGGGHAGTEAAAAAARMGANTLLVTETIGEMSCNPSFGGIGKGTLVREIDALDGLCGRVCDEAGVQFRVLNQSRGPAVWGPRAQMDRDLYKQYMQDTIFTY-PNLSVKAAAVEDLLANGETIKSKAVVLTTGTFLRAQINIGLECFP-AGRIGDGLGRTLF-GFALGRLKTGTPPRLEGKTINYSQLGDNPPLPFSFMN-QLK-CFMTLTSTAGHKIIRENIHLSRHVME-ETRGPRYCPSVESKILRFTDKASHQVWLEPEGYNTTVVYPNGISTTLPRELQLQFLRTIPGLENVEMLRPGYGVEYDYIDP-RQLRESLETQKINRLFLAGQINGTTGYEEAASQGILAGINAALLDRADGYLGVLVDDLLSKGAPEPYRMFTSRAEYRLHLRSDNADARLTAKGGCVGPD-RSAFEILQRITIDARYYRREESTVIPFDFDYKSLKPRTIKEASLLHGTTPTALILLLQ Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MH-QIK-CYQTHTTPATHAFIRAHLHTTKHIQT-TISGPRYCPSIEAKLLRFADKQRHLIWLEPEGLDSDSIYPNGISNSLPANHQLTMLRTIPGLENVHMLRPAYGVQ--------------------GLFLAGQINGTTGYEEAAAQGVVAGANAGLVGRGNGYVGVLIDDLVTRGVSEPYRVFTARSEYRLALRADNADSRLTRMGGF------SAYTVL-RVKTDAVYYEREVNAEIPADLDYGQVRPTSLHALKAMEGINPSTVMTILR Cioin YDVIIVGGGHAGCEAASASARVGARTLLLTSTIGEMSCNPSFGGIGKGHLIREIDALDGICGRICDISGIQYRMLNRKKGPAVWGPRAQIDRNLYRENMQTEIHNT-INLDVMEGSVEDLLSDGTMLHAKGVVLTAGTFLRGQINIGMIVKG-AGRIGDGLARTIL-GFEMGRLKTGTPPRIAKDSVNFSYGGDMPPHPFSFEN-QLT-CYTTHTKPELEKCILDTLHMNKHVIE-EVNGPRYCPSIESKVLKFKEK-SHMCWLEPEGLTSNVIYLQGFSCTMPEENQTEAVRMIQGLENAEITRPGYGVEYDYMDP-RQVSTTLETYKVKGLYFAGQINGTTGYEEAAAQGLIAGVNAARVTRSEGYIGVLLDDLTTMGTNEPYRMFTSRTEFRMTLRPDTADERLTEKGGCVSEK-RNAFHFLNRLLSSAVYVKREERLIIPDHIDYVNMRPGNIAAASRIQGVTPASLVQLLK CocheC53 YDVIVIGGGHAGCEASAAAARAGARTALVTENLGVCSCNPSFGGIGKGTMLREIDALDGVVGRIVDKAGVQFRVLNRKKGPAVWGPRAQIDRALYKRYMKDEMLSY-KGLSVLEGSVADILESGEIIPTGNVVITTGTFLGGEIHIGLEAYP-SGRMGEGLSKSLA-GFTLGRLKTGTPPRLDGKTIDYKQEGDNPPMPFSYLN-QLL-NHETRTNEATHDVIRKNLDKSIHIRE-TVKGPRYCPSLESKVIRFADKSSHIVWLEPEGFDNDIIYPNGISCTVPADVQNTMLKTIKGLENVTMLQPGYGVEYDYVDP-RHLRSTLETKNISGLFLAGQINGTTGYEEAAGQGVIAGINAGLLTRADGYIGIMIDDLITKGVSEPYRMFTSRSEYRMSARADNADSRLTSLGGIISDT-RSAYDLLHRVHIEATYWLKDEKLQLPIDLDYEAIRPESVGMARRVEGVTPTGALRLLQ Coere1 YDVVVIGGGHAGCEACTAAARAGASSLLVTETIGEMSCNPSFGGIGKGTLVREVDAMDGLCGRMADLGGVQFRILNRSKGPAVHGPRAQVDRVIYKRNMLQALQSY-EGLTIKAGSVADILESGEIIRTRKVVITTGTFLGGQILIGLETYS-SGRRGEGLSKSLA-GFRLGRMKTGTPPRLDGRTIDYSQFGDMPVTPFSYMH-QVV-CYQTRTTAEAHDIIRANFDKSIHIRE-TVQGPRYCPSLESKIKRFTSKHSHAIWLEPEGLATNTIYPNGISNTMPADIQQQFLRKIPGLENVTMTYPGYGVQYDHIDP-RELKRNLETKRVNGLYMAGQINGTTGYEEAAAQGILAGSNAGLLDRSDGYLGVLIDDLITRGVEEPYRVFTARSEYRISSRADNADLRLTRRAGLVRDSARSALDMVRRVVTEAAYFKRDEGLRLPANIDYSQIRPDTFGAAKRIDGITPGGIFALLK Conco1 YDVIVIGGGHAGCEASAASARMGANTLLLTDTIGELSCNPSLGGVGKGILVREVDALDGVCGKVGDLAGIQFTVLNRSKGPAVYGPRAQLDRKLYKHHMQQILNKQ-ENLSIMEGSAFDILKDGTKIKCNNVILTTGTFLNGEIHIGLTVYP-AGRIDEGLSESLA-GFALGRMKTGTPPRLDGDTIDYTQPGENPPTPFSFMH-QIM-CHQTKTNEQSHQVIR-------------------------------------------------------------------------------------------------------------------------------GIIAGINAGCLDRGDAYIGVLIDDLVTKGVEEPYRIFTSRSEYRLCLRSDNADLRLTERGGCVSQE-RDAYEMLESVWIEGMYLKLNSSLQIPLAFDYEKLKPTTLQQAQSIPGLSPAAVIRLMK Conpu1 HPVCVIGGGHAGCEAATGAARTGARTVLLTDTIGELSCNPSIGGVGKGTLVREVDALDGVMGRVADKAGIQFRMLNASKGAAVWGQRAQVDRKLYKQHMQDVMFNY-PSLDIHAGSVFDLLENGDVIKCSQVVICTGTFLGGEIHIGMKRFP-AGRMNEGLSASLA-GFQLGRLQTGTPARLDRNTIDFGHAGDAEPVPFSFLN-QIL-CYQTYTTPETHRLIKDSMQFSVHIQE-TRKGPRYCPSLEAKITRFADKDSHKIWLEPEGYDSDLIYPNGLSCSMPEELQEPMMRTIPGMESVKMVKPAYGVEYDHVDS-RELTETLETKRIQGLFLAGQINGTTGYEEAAAQGCIAGINAGLLTRADGFVGVMIDDLIRKGAEEPYRMFTSRSEYRMTLRSDNADLRLTELGGIVSDA-RSAFEMLTRVGVDGKYFLSDEQRLLPPDLDYSAIRPSSLGAAKRVEGMTPSSYLYLAR Copci YDVCIIGGGHAGCEAAAGAARTGARTVLLTETIGELSCNPSIGGVGKGTLVREIDALDGVMGRVADKAGIQFQVLNRSKGAAVWGPRTQIDRTLYKQNMQKILHNY-PNLDIKAGSVFDLLDSGEIISCSQVVICTGTFLSGEIHMGLKRIP-AGRIGDGLSASLA-GFKLGRLQTGTPARLDGKTINFEQEGDAEPLPFSYMN-QIT-CFKTYTNPSTHQIVKDNLHQCVHIQE-TKKGPRYCPSLEAKILRFGDKDHHTVWLEPEGYDSDVIYPNGISCSLPEELQEPMMRTIPGLEKVKIVRPAYGVEYDYIDP-RELNPTLETKRIKGLFLAGQINGTTGYEEAAAQGIVAGINAGLLTRADGFTGVMIDDLTVKGAEEPYRMFTSRSEYRMTIRSDNADLRLTTKGGVVSDP-RDAYYMLARVDIEGHYFMEDESLLLDPRMEYREVRPTTIGAAKRIEGMTPTSVVYLLK Croqu1 WDVIVLGGGHAGTEAASAAARSNASTLLVTATVGEMSCNPSFGGIGKGTLIREVDALGGICGKACDEAGIVFQMLNRSKGPAVYGPRAQMDRQLYKQAVQNQLKSH-DRLSVKEGNVTELLDTGEILRCRALVIATGTFLGGEIHVGMESTP-FGRIGESLSNSLA-GFKLERLKTGTPPRLLKRSIDFSQNGDQSPSPFSFVN-QLC-CWKTHTTSRTHVIVKENLENTVHIRE-EIRGPRYCPSLESKVIKFADRESHIVWLEPEGFESELIYPNGLSTTIPPEAQLQMLRTIPGLETVEMDQPGYGVEYDHVDP-RELNNTLETKRIKGLFLAGQINGTTGYEEAGAQGVLAGINAGLLTRANSFIGVLVDDLITKGVQEPYRMFTSRSEFRVSLRADNADLRLTTKAGVIDDD-RSAFDVLRRIEVEALYLEADELCRLPTGLDYHALRPETLGAAKRLEGIDPNALILLSK CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 FDVVVIGGGHAGSEASAAAARAGARTALVTDNLGVCSCNPSFGGIGKGIILREIDALDGLAGRVIDRAAVQFKVLNRKKGPAVWGPRAQIDRGLYKQYMREELTNNCPGLEVVEGRALDILESGEVIRTKHVIITTGTFLGGEIHVGLQVYS-SGRLGEGLSKSLA-GFQMGRLKTGTPPRLDRKTINFDQEGDDPPMPFSYMN-QLL-CHATYTNEATHDVVRANLDKTIHIRE-TVKGPRYCPSLESKVIRFGHKNRHIVWLEPEGFDSDVIYPNGLSMTIPADAQEQLLRTIPGLEDVKMLQAGYGVEYDYVDP-RSLRSTLETKAIRGLWLAGQINGTTGYEEAAGQGIIAGINAGRLSRSDGYIGVMIDDLVTKGVSEPYRMFTSRSEYRLSTRADNADSRLTRKGGVVGDK-RDGMDILTRVEIEAAYLRRDEQLRLPTDLDYQGVQPETLAQARRLEGITPAGCLRLLA Debha1 HPVIVIGGGHAGCEAATGSARSGTFTTLVTDKIGTASCNPSMGGVGKGTLLREIDALDGVSARITDKAGIHFKILNASKGAAVHGPRAQIDRKIYLTEMQKEILNY-ENLKVIEAQVEDILSDGRILKCSKVVVTTGTFLGGEIHIGLSCHP-AGRMGEGLSKTFA-SFRLGRLKTGTPPRLSSKTIDYTQLSDYPPQPMSYLN-QLMKCHMTSTTPELHKLIADNLDKSIHIRE-TVKGPRYCPSIESKIIKFPQKSTHLVWLEPEGLDTDLVYPNGISCTMPAEIQETMVRMMPGCENVTMLQPGYGVEYDYVDP-RELKMTLETKLVDGLYLAGQINGTTGYEEAAAQGCLAGINAGLIHRSDGYLGVLVDDLITKGVEEPYRMFTSRSEFRISIRSDNADKRLLQKGGVVSES-RDGWKLLGRINVESTYYQADETLLLPLNYNYTNEQPTTIGQARRIQGVTPAAIFELFK Dekbr2 KPVIVVGGGHAGVEAATGSARSGAQTTIITYKIG------------------EIDALDGSAPRIVDKAGIQFKVLNRSRGAAVWGHRAQIDRELYRCEMEDYVANY-PNLEVYEGKIEDLLGNGEMLRCEKVVITTGTFLGAEIHIGSKAWP-AGRIGEGLSDTFI-HFRMGRLKTGTPPRLSGRTIDYTEYGDMPPEPMSFIH-QIS-CYSTHTTEPLRNLVLANLDKSIHIKQ-DVKGPRYCPSLESKLIRFKDKKEHRVWSEPEGFHTDVMYPNGISNTMPEDIQDKSLRMIIGLEHVKMLQPAYGVEYDYIDP-RELRRTLETKLVDGLFLAGQINGTTGYEEAAAQGIVAGINAALLDKADGYIGVLIDDLITKGVTEPYRMFTSRSEFRVSARSDNADRRLTELGGCIRDE-RSAFEILVAIKIEGNYFRSDEKLPLPIDFDYSSIKPETIGQARRIQGVTPVAIFELYR Dicdi FDVIVIGGGHAGTEASAASARVGSKTLLITDTIGVMSCNPSIGGVGKGNLVREIDAIGGIMGLAADESGCQFKVLNQSKGSAVHGPRAQIDRELYRESIHNLLWK--GNLSIKEGMVEDILDNGEIIKCKKVVITTGTFLGGIIHIGNKRIP-SGRMGDALSLTLI-GFELGRLKTGTPPRLDGKSIDYSQVGDEIPLPFSFSN-QLK-CFMTRTTEESHQIIIDNLSSRPA----KGLGPRYCPSIETKIERFQGK-THQVWIEPEGYTTDVIYPNGISISLPEDVQMKFLKTIPGLENVKMLKPGYAVEYDYIDP-RELNHTLETKKISGLFLAGQINGTTGYEEAGAQGIVAGINASLISRSEGYIGVLIDDLVTLGVTEPYRMFTSRSEYRISLRAHNSDQRLTEKAGSASNH-QSLFEILSIIDSECKYLRKRENQLIPPSLNYWDIRPTNFSSASKISGITPSALFSIQV Dmel YDVVVIGGGHAGTEASAAAARMGSRTLLLTETIGEMSCNPSFGGIGKGHLMREVDALDGVCARCCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLYKKAVQQELHST-PNLEIRAAAVDNLLANGEVVRSRSVVLTTGTFLRAHINIGLEVRP-AGRIGDALGEAIL-GFRMGRLKTGTPPRIAKDSVDFSHEGDDPPMPFSFLN-QLP-CYLTYTTPKVSDIVRDNLHVNRHVTE-EITGPRYCPSIESKILRFGAK-VHQVWLEPEGLDSSLVYPQGISCTLPHDQQVELVHAIQGLEKAVVVQPGYGVEYDFIDP-RELYPTLETKRVPGLFFAGQINGTTGYEEAAAQGIIAGANAAGISRTEGYIGVLIDDLTSLGTNEPYRMFTSRAEFRLSLRPDNADMRLTQKGGLVSSD-RSAFDMLERLKIEALYVRREERLSIPADIDYFSKQPQTIAAASRIQGVTPSTIVRILK Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba YDVIVIGGGHAGTEAAAASARAGARTLLLTSTLGEMSCNPSFGGVGKGTLVREVDAMGGVCGLGVDAAGIQFRVLNRSRGPAVWGPRAQVDRKLYKRFVQPYLAQY-PGLELREASVEDLLGDGSVVRSKSVIITTGTFLRANIFIGMETWP-AGRMGSGLAETML-GFRVDRLRTGTPPRIRKSSINFEQPSDEVIMPLSYMT-LVS-CFQTRTNAATQAIIFPRIQDSLHIKE-EVTGPRYCPSFEAKLIRFPERPGHIVWLEPEGLDSDVVYPNGYSLSVPVDAQLAGLRTMPGLENAEIIQPGYGVQYDYMDP-RDLKRTLESKLVDNLFLAGQINGTTGYEEAAAQGLIAGVNAARVDRADAFIGVLIDDLTTKGTSEPYRMFTSRSEFRITVRADNADERLTPKAGIVPPE-RNAFKLLERVLVRGRYYRREEFLRIPEDIDYSSIRPATIAEAAKLQGVTPGNLLQLVK Fomme1 YDVVVIGGGHAGCEAAAGSARTGARTLLLTSTVGALSCNPSVGGVGKGTLVREVDALDGLMGRVSDKAGIQFQVLNRSKGPAVWGQRAQIDRKLYAKHMQAELFHY-GNLEVRAGSVFDLLESGEQINCSQVVICTGTFLSGEIHIGPRRLP-AGRLNEGLSGSLA-GFKLGRLQTGTPARLAANSINFDLSGDPIPLPFSYMN-QIF-CYLTQTTPETHNIIRDNMHKNIHIQE-TRKGPRYCPSLEAKVRRFPSKSEHKVWLEPEGYDSDVIYPNGISCSLPEEIQEPMMRTIPGLENVKMVRPAYGVEYDHIDA-RELSPSLETKRIRGLFLAGQINGTTGYEEAAAQGVIAGVNAGLLTRADGFIGVLIDDLILKGAEEPYRMFTSRSEYRMTLRSDNADLRLTPKGGIVSNE-RSAFHMIDRAEIEARYFLEDEELNLSPSLDYDNIRPTSLGSAKRMEGMTPASLVALLE Fusgr1 YDVVVIGGGHAGAEACAAAARAGARTALITDNLGTCSCNPSFGGIGKGTIIREIDALDGLAGRIIDKSGVQFHILNRRKGAAVWGPRAQIDRDLYKKHMKAELTSY-PNLSIVLDSVSDILESGQILPTNKVIITTGTFLGGEIHIGLDAYP-AGRLGEGLSKSLA-GFQLGRLKTGTPPRIDGASINYEQYGDDPPSPFSYLN-QLT-CSVTYTNEMTHDVVRDILDKTIHIRE-TVRGPRYCPSLESKIIRFADKTRHIVWLEPEGFDSPVIYPNGLSMTIPAEAQEQVLRTIPGLENSKMLQPGYGVEYDYIDP-RGLKSTLETKAISGLYLAGQINGTTGYEEAAGQGVLAGINAGRLTRSDGYIGIMVDDLITKGVTEPYRMFTSRSEFRMAARADNADFRLTPKGGVISDK-RDGIDMLNRVAIEAFYFTNDERVRIPIDLDYGEIKPENLAQARRVEGVTPSGSLRLLA Galma1 YDVCVIGGGHAGCEAAAGAARTGARTILLTETVGELSCNPSIGGVGKGTLVREVDALDGLMGRVADKAGIQFHILNRSKGAAVWGPRAQIDRTLYKRNMQQILFNY-PCLDVQAGSVFDLLENQEVIHCSQVVICTGTFLSGEIHMGMKRFP-AGRLGDGLSASLA-GFKLGRLQTGTPARLDRNTIDFSQVGDISPTPFSYLN-QVF-CYQTATTPETHQMVKDNIHLSVHIQE-TRKGPRYCPSLEAKILRFGNKAKHTVWLEPEGYDSDVIYPNGISCSLPEEVQEPMMRTIPGLENVKMVKPAYGVEYDYIDP-RELGPTLGTNRVKGLFLAGQINGTTGYEEAAAQGAVAGINAGLLTRADGFTGVMIDDLIVKGAEEPYRMFTSRSEYRMSIRSDNADLRLTEKGGAVSDA-RDAFQILARIGIDGQYFSEDESLALDPKLDYASVKPTTIGAAKRMEGMTPPSLISLLK Ganpr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 FDVIVIGGGHAGSEACTAAARTGAKTLLLTDTIGEMSCNPSFGGIGKGILVREIDALDGLCGKISDLSGIQFHILNRSKGPAVHGPRAQIDRKLYKKNMQEHLFNY-PNLTVMAGSVHDILESGKVIYASKVILTTGTFLQGEIHIGRTMYP-SGRFGEGISKTLA-GFKLGRLKTGTPPRLDGRTINYKQHGDIPATPFSYLH-QIM-CYQTKTNTETHKIILDNLSETMHIRE-TVKGPRYCPSIEAKVIRFKDKQGHIIWLEPEGLDTEIVYPNGISMSLPESTQYNVIRTIPGLENVEMIRPGYGVEYDHVDP-RELNPTLETHRIKGLYLAGQINGTTGYEEAAAQGIIAGINAALLDRADAYIGVLIDDLITKGVEEPYRMFTARSEYRLSLRADNADMRLTRKGGCVSNH-RSAVDIIRRLHIEASYFRKDEEMILPEDLDYDLVRPTTLGAAKRIEGMTPASVVTLLK Hisca1 YDVVVIGGGHAGSEACAAAARLGARTALVTSNIGVCSCNPSIGGIGKGTMIREIDALDGVAGKVADKSGIQFRILNRSKGEAVWGPRAQIDRVLYRQNMLDELSNT-PGLSIVEGKVGDILESGEVIPTGRVIITTGTFLGGEIHIGLDVFP-SGRLGEGLSRSLA-GFQLGRLKTGTPPRLDKKTIDFSQPGDSPPIPFSYLNDQLP-CWSTYTNEAAHQIVRDNLDKSIHIRE-TVKGPRYCPSLESKIIRFKDKQRHMIWLEPEGFEDEVIYPNGISMTIPADAQLAMLRTVAGLENVRMLQAGYGVEYDYVDP-RSLRPTLETKLISGLYLAGQINGTTGYEEAAGQGILAGINAGLLSRSDGFIGIMVDDLITKGVSEPYRMFTSRSEYRISTRSDNADLRLTARGGVVGDK-RSAFDLLHRVAVEGRYFEKDEALLLPPDIDYSLIRPESIGMARRIEGMTPVAALKLLV Klula1 VDVVVVGAGHAGCEAAAGSARSGAETMLITDKIGTCSCNPSMGGVGKGTLLREVDALDGVAAKVTDKAGIQFKMLNQSRGAAVWGPRAQIDRELYLKEMQNALQNY-PNLTLFSGKVKDVLDNDEVIKCSKVVISTGTFLSAEIHIGLKTIP-AGRIGEGISHTLA-GFKLGRLKTGTPARLDGRTIDFTQYGDDPPYPMSYMN-QIL-CYGTRTTSELHDYLKLNLHQSIHIRE-TVKGPRYCPSLEAKIIRFSDKDSHRIWLEPEGLNTDVIYPNGISNSMPEDVQEIMMRMIPGLENVKILQPAYGVEYDYVDP-RELKQTLETKLIDGLYLAGQINGTTGYEEACAQGVVAGINAGLLSRSDSYTGVLIDDLITKGVEEPYRMFTSRSEFRVTVRADNADFRLTEKGGVVSEE-RNAWDMFLKINVEAKYFQADENMLLPLNYDYTKIQPATIGQARRIQGMTPASIFELYK Lacbi2 YDVCVIGGGHAGCEAAAGAARTGTRTVLLTETIGELSCNPSIGGVGKGTLVREVDALGGIMGGVVDKAGIQFQILNRTKGAAVWGPRAQIDRKLYKKNIQNVLHNY-PNLDIRAGSVFDILETGEIIPCSQVVICTGTFLSGEIHIGLNRFP-AGRLGEGLSASLA-GFKLGRLQTGTPARLDISTIDFGQDGDVVPSPFSFMN-QVY-CYKTATTPETHQIIKDNIHLSVHIQE-TRKGPRYCPSLEAKVLRFGHKDHHTVWLEPEGYDSDLIYPNGISCSIPEELQETMIRTIPGLENAKMVKPAYGVEYDYIDP-RELGPTLETNRIKGLFLAGQINGTTGYEEAAAQGIVAGINAGLLTRADGFTGVMIDDLIVKGAEEPYRMFTSRSEYRMTIRSDNADMRLTEKGGVISDE-RSAFQMLSRIDVEGQYFMEDESLLLDPRMEYSTVKPTTIGAAKRMEGMTPTSVVYLLK Lenti61 YDVCVIGGGHAGCEAAAGAARAGARTLLLTNTIGELSCNPSMGGVGKGTLMREVDALDGLCSRVTDEAGIQFSILNRSKGAAVWSPRAQVDRKLYKKHMQAALHNY-PNLDIHAGSVFDLLDSGEVITCSQVVICTGTFLSGEIHIGMKRFP-AGRMNEGLSASLA-GFRLGRLQTGTPARLAKDSIDFSQKGDEVPLPFSFMN-QVV-CWKTETTSETHQIVRDNIGNCVHIQE-TKKGPRYCPSLEAKVTRFPQKSAHTVWLEPEGYDSDLIYPNGLSCSLPEEVQEIMYRSVPGLENVKLVRPAYGVEYDHVDA-RELGPTLETKRIKGLFLAGQINGTTGYEEAAGQGVVAGINAGLITRADGFIGVMIDDLIVKGAEEPYRMFTSRSEYRMTLRSDNADLRLTENGGAVGDP-RSAFELLMRVETDAVYFMEDESLALDPQLDYQSVRPTSIGAAKRMEGMTPTSMIYLFR Malgl1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSFLH-QLY-CFGTRTTPATHVIVHQEVQGDDYEMT-KYTGPRYCPSLEVKVLRFAHKESHPVWLEPEGLTGHVLYPNGLSCSLSPDAQTRMVRTIPGLEHAVLLRPGYAVEYDHVDP-RELLPTLETRRIRGLAMAGQINGTTGYEEAGVQGVLAGLNAGLVSRSDGFVGVMLDDLRLQGVMEPYRMFTSRSEYRLSLRADNADLRLTPLVESITDT-RSALDMMERLATQASYFQRDEALALPVDMAFAELKPRTLGEAKRIAGCTPAAYAVLWR Mellp23 YDVIVLGGGHAGTEAASGAARCNASTLLVTKTVGEMSCNPSFGGIGKGTLVREIDALGGICGKACDEAGIVFQMLNRSKGPAVYGPRAQMDRQLYKQSVQNQLQKF-NQLAIKEGTVTDLLDTGEIIKCKSLVIATGTFLGGEIHIGMKSSP-FGRIGESLSNSLV-GFKLERLKTGTPPRLLKNTINFSQNGDQPPTPFSFMN-QLC-CWKTHTNAQTHDIVRKNLDKTVHIRE-EVRGPRYCPSLESKVVKFPDRDSHMIWLEPEGYESDLIYPNGLSTTIPPDAQLQMLRSIQGLEAVEIHQPGYGVEYDHVDP-KELTNTLETKRIKGLFLAGQINGTTGYEEAGAQGVLAGINAGLLTRADSFIGVLVDDLITKGVQEPYRMFTSRSEFRVSLRADNADLRLTKKAGVIDED-RSAFDVLRRIEVEALYLEADELCRLPPNLDYHTLRPETLGAAKRLEGIDPNALILLSK Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr YDVVVIGGGHAGCEAAAAAARTGARTALVTETIGEMSCNPSFGGVGKGILLREVDALGGVAPTICDRAGIHFRVLNRSKGPAVWGPRAQIDRSIYRSEMQQHMASQ-PNLDLIAAAVEDILGNGQIIGTRAVVVTTGTFLRGVINIGAYFTP-AGRKGEGLAQTLF-GFKLGRLRTGTPPRIKKSTVCFDQPSDYPATPFSYLN-FIQ-CHLTHTNSAAHQLVHDTLHENNHVRQ-DALGPRYCPSIESKANR------HQVWLEPEGLDSDVIYPNGISMTMPEEAQLRFVRSIAGLENAQITQLGYGVSYDFVDP-RQLHRTLETKMIHSLFLAGQINGTTGYEEAASQGIIAGINAALVDRTQAYIGVLIDDLVTKGVLEPYRMFTSRAEYRLSLRSDNADTRLTALGGAVDEP-RMAFGFVERVKIEAMYYRRQASLEIPPGFAFEKVAPRTIGDAAQIQGITPDALARLVR Morel2 YDVIVVGGGHAGSEACAAAARTGAKTLLLTDTIGEMSCNPSFGGVGKGVLVREIDALDGLCGRISDLAGVQFRILNRSKGPAVHGPRAQIDRKLYKKHMQAALNEY-PNLTIKAGSVSDILESGEVIHAPKVVITTGTFLRGEIHIGLEAYP-AGRINEGLSDSLA-GFELSRLKTGTPPRLDGKTIDFSQYGDQPPSPFSYLN-QLA-CYQTSTNPKTHEIIRNNLHKSIHIRE-TVKGPRYCPSIESKIMRFTTKEAHTIWLEPEGYDNDVIYPNGISMTLPEKEQIEMLRTIKGLENVTVLRCGYGVEYDYVDP-RELKRTLETHRIHGLYLAGQINGTTGYEEAAAQGVLAGINAGLLTRADAYIGVLVDDLITKGVEEPYRIFTSRSEYRLTLRADNADLRLTRKGGCVTDY-RSAIEMLNKIEIEGAYFMRDENMELPSDIDYSAVRPATLGAAKRIEGITPTSIVELLK Mucci2 FDVIVIGGGHAGTEACAAAARSGAKTLLLTDTIGEMSCNPSFGGVGKGVLVREIDALDGVCGRISDLAGIQFKVLNKSKGPAVYGPRAQIDRKLYKKHLQSYLKDY-PNLTIQSGSVSDLLENGQVIRASNVIITTGTFLGGEIHLGLKVWP-AGRIGEGLSNSLA-GFQLARLKTGTPARLDGRTINYEQEGDNPPSPFSYLN-QIL-CHQTRTNPQVHKYIADHFDQSIHIRE-TVKGPRYCPSLESKIKRFSTKEAHNIWLEPEGLDTPVVYPNGISNTMPEDVQLNFLRMIRGLENVDMLKPAYGVEYDHIDP-RELRSTLETKRISGLFLAGQINGTTGYEEAAAQGVMAGINAGLLDRSDAYIGVLIDDLITKGVEEPYRVFTARSEYRLLLRADNADTRLTEKGGVIGKE-RSGMDLLERVMIEGRYLKRDEHLTLDINLDYLQM----EGAAKRIEGMTPAAMVVLMK Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 FDVVVIGGGHAGSEACAAAARAGARTALVTENLGVCSCNPSFGGIGKGIMIREIDALDGLAGRVIDKAGVQFRVLNRKKGPAVWGPRAQIDRALYKKHMRAELESY-PNLSLVYNSVSDILESGEVLPTSQVIITTGTFLGGEIHIGMEAYP-SGRMGEGLSKSLA-GFKLGRLKTGTPPRLDKKSINFNQYGDDPPNPFSYLN-QLH-CWATYTNHATHEIVRANLDKTIHIRE-TVKGPRYCPSLESKIIRFSEKERHLVWLEPEGFDNDIIYPNGLSMTVPAEAQLALLRTIPGLEDVIMTQPGYGVEYDYVDP-RSLKRTLETKAIRGLWLAGQINGTTGYEEAAGQGIVAGINAGRLSRADGYIGVMIDDLITKGVSEPYRMFTSRSEFRMTTRSDNADSRLTALGGVVGDR-RSALEILERTFIEGLYFEREEDLRLPLDLDYDQIRPESLAQARRIEGITPAGCMRLLA Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YDVVVIGGGHAGSEACAAAARSGARTALVTENIGVCSCNPSFGGIGKGTMIREVDAMDGVAGRIIDKAGVMFRVLNRSKGPAVWGPRAQIDRDLYKRYMSEELAGT-ENLNIVEGKVADILESGEVISTGRVVITTGTFLGGEIHIGMDVFP-SGRMGEGLSKSLA-GFQLGRLKTGTPPRLDKKTIDFSQKGDSPPHPFSYLNGQLT-CWMTHTNEAAHEIIRANLDKSIHIRE-TVRGPRYCPSLESKIIRFKDKTQHQIWLEPEGFANDVIYPNGISMTVPADAQYAMLRVVRGLENVTMLQPGYGVEYDYIDP-RNLRPTLETKLISGLYLAGQINGTTGYEEAAGQGIVAGTNAGLLTRSDGFIGIMIDDLITKGVSEPYRMFTTRSEYRISTRSDNADLRLTRMAGVVSDK-RSALDILTRVAIEGRYFQQDENLLLPADLDYSMVRPVSVGMAKRIEGVTPVGALRLLM Phybl2 FDVVVIGGGHAGTEACTAAARVGARTLLITDTIGEMSCNPSFGGVGKGVLVREVDALDGVCGRIADLAGIQFKVLNKSKGPAVYGPRAQIDRKLYKKHLQEYLEDY-PNLTIQTGSVADLLDNGHIIKTSNVVITTGTFLGGEIHLGLKAWP-AGRIDEGLSNSLA-GFQLARLKTGTPARLDGRTINYEQEGDNPPSPFSFLH-QVL-CHQTRTNPSVHKYIAENFDQSIHIRE-TVKGPRYCPSLESKIKRFGDKTGHAIWLEPEGFDSHLVYPNGISNTMPEDVQLNFLRMIRGLENVDMVRPAYGVEYDHVDP-RELRSTLETKRISGLFMAGQINGTTGYEEAAAQGVMAGINAGLLDRSDAYIGVLIDDLTTKGVEEPYRVFTSRSEYRLHLRADNADLRLTSKGGAVGEE-RSGVDILERLLIACRYLKRDEDLKLDINLEYSRMRPETLGAAKRVEGITPAAMVVLMK Picst3 FPVVVIGGGHAGCEAATGSARSGTPTTLITDKIGTASCNPSMGGVGKGTLLREVDALDGVAARITDKAGIHFKILNASKGAAVHGPRAQIDRKIYLEEMQKEILNY-PNLLVLEALVEDILGDGSIVGCSKVVVTTGTFLGGEIHIGLTAYP-SGRIGEGLSETFA-GFKLGRLKTGTPARLSSKTIDYSQPSDYPPQPISYMN-QLVNCYQTSTTPEFHKLISENLDKSIHIKE-TVKGPRYCPSIESKIIKFPQKQSHMVWLEPEGLDTDLVYPNGISCTMPADIQEQLVRMMPGCNNVKMIQPGYGVEYDYVDP-RELKMTLESKLVDGLYLAGQINGTTGYEEAASQGCLAGINAGLLTRADGYLGVLVDDLITKGIEEPYRMFTSRSEFRISIRSDNADRRLTEKGGVVSEE-RDGWKLLNRIDVESDYYAADENLLLPVNYNYNYEQPKTIGQARRIQGVTPAAIFELFK Plicr1 YPVIIIGAGHAGLEAAFASARVPARTLLLTATIGAMSCNPSIGGVGKGTLVREVDALGGEMGVAADAAGIMFGMLNRSKGAAVWGPRAQISRTLYRDHMQAAVATY-PGLDVRAGSAWDLLERGERIACSQVVICTGTFLAGEIHIGPTRIP-AGRHSDGLSSTLA-RLRMSRLQTGTPARLLRESIDFAQEGDREPAPFSFLN-QVT-CFRTRTTPATHAVVRAHMHRSVHIPE-TRKGPRYCPSLEAKVLRFPDRDGHDVWLEPEGYDSDLIYPNGLSNSLPPDAQLAMLRTVPGLERVEMVRPAYGVEYDYVDP-RELHATLETKRIQGLFLAGQINGTTGYEEAAAQGVVAGLNAALLGRADGFVGVMIDDLVTKGAEEPYRMFTSRSEYRITMRCDNADLRLTEKAGAIPDA-RSAHDLLGRVDVDALYFLSDTALALDPHTDYTSVRPGSYGAAKRMEGMTPAALVYLLR Polpo FDVVVIGGGHAGTEACAAASRVGASTLLITNTIGVMSCNPSIGGIGKGNLVREVDALGGVMGLAADASGCQFKILNQSKGSAVHGPRAQIDRDLYQQEIHTLL-----NLNIREAMVEDMLNDGSVIKTKKVVITTGTFLGGVIHVGNKTVL-AGRVGDKLSQTLF-GFALGRLKTGTPPRLDGKSIDYTQNGDEKPTPFSFLN-QLQ-CFMTRTTEQSHQIILDNLDTRPA----KGLGPRYCPSIETKIERFQGR-THQVWLEPEGYNTDVIYPNGISISLPEDVQLQFLKTIPGLENVVMLRPGYAVEYDYVDP-RELRSTLETKKVKGLYFAGQINGTTGYEEAAAQGIVAGINAALVDRSEGYIGVLIDDLVTLGVTEPYRMFTSRSEYRISLRAHNSDQRLTQKGSSVTKE-RSIFEILPVIESECQYFKREESREIPEAINYWEIRPPTLGSASRVPGVTPSGILAILS Pucgr2 WDVVVLGGGHAGVEAASAAARTNSRTLLVTSTVGEMSCNPSFGGIGKGTLIREIDALGGVCAQACDEAGIVFQMLNRSKGPAVYGPRAQMDRGLYKEAIQRQIKSQ-LNLEVKEGTVTDLLESGETLNCKALVIATGTFLGGEIHIGRKTSA-FGRIGESLSNSLS-GFKLARMKTGTPPRISKSSIHFDQQGDVPPKPFSFTN-QLC-CWKTHTTKATHEIVQENLHLSSYVRE-EVHGPRYCPSLEAKVTRFSHRDSHMIWLEPEGFHSDLIYPNGISTTMPEDAQLKMMRTIPGLEKVEMVQPGYGVEYDHIDP-RELKNTLETKAIQGLFLAGQINGTTGYEEAAAQGVLAGINAGLLTRADSFIGVLVDDLTSKGVQEPYRMFTSRSEFRVALRVDNADLRLTEKAGVIDDR-RTAFDVLRRVEVEALYLIEDENMILPSSINYSELRPLTLGVAQRLQGIDPGELILLRK Punst1 YDVCVIGGGHAGCEAATGSARTGARTALLTDTIGELSCNPSIGGVGKGTLVREVDALDGVMGRVADKAGIQFQILNRSRGAAVWGPRAQIDRKLYKKHMQDTLKAY-PNLDIRGGSVFDLLDSGEIISCSKVVICTGTFLSGEIHIGMKRFP-AGRMGEGLSGSLA-GFKLGRLQTGTPARLDKHTIDFTQDGDVKPLPFSYLH-QVA-CFQTRTTQETHQIVRDNLHLSCHIQE-TKKGPRYCPSLEAKILRFGHKESHVIWLEPEGYDSDLIYPNGISCSLPEDVQKAMIHSIPGLRNARIVRPAYGVEYDYVDP-RELGPTLETKKIEGLFLAGQINGTTGYEEAAAQGAVAGINAGLLTRADGFLGVMIDDLIVKGAEEPYRMFTSRSEYRMTIRSDNADMRLTEKAGAVSDA-RSAWDMLDRLTIEAVYFMEDESLILDPNMDYHAIKPTSIGAAKRMEGMTPSSIIYLLK Rhior3 YDVIVIGGGHAGTEACTAAARSGAKTLLLTDTI------------GKGVLVREIDALDGVCGRISDLAGIQFKILNRSKGPAVYGPRAQIDRKLYKKHMHEYLKDY-PNLTIKAGSVADL-------------------LGGEIHLGLKSWP-AGRIGEALSKSLA-GFKLGRMKTGTPARLDGRTINYKQEGDNPPTPFSYLH-QIL-CYQTRTNAQVHKYISDHFDQSIHIKE-TVKGPRYCPSLESKIQRFTSKDGHNIWLEPEGLDTHVVYPNGISNTMPEDIQLNFLRMIQGLENVDMLKPAYGVEYDHIDP-RELRSTLETKRISGLFLAGQINGTTGYEEAAAQGIMAGINAGLLDRSDAYIGVLIDDLITKGVEEPYRVFTARSEYRLLLRSDNADTRLTARGGVIGQN-RS-----------GRYMKRDENLQLDINLDYKKMRPETLGAAKRVEGVTPAAMVVLMK Rhoto1 YETLVIGGGHAGCEAAAASARAGARTLLLTDTIGEMSCNPSFGGIGKGTLVREVDALDGLCGKICDKAGIQFHVLNKSKGPAVYGYRAQIDRKLYKNEMQAVLSSY-PNLDIRKAAVQDILDSGEVIPCKSIVICTGTFLDSELHIGMDIIPKKGRINETLSDSLA-GFELGRLKTGTPPRLAKDSINYEQVGDDPAKPFSFLT-QIS-CFQTATNEASHAIIRDNIHRTVHVRE-TVKGPRYCPSIESKVLRFGDKLSHVVWLEPEGYDSDLIYPNGISITLPAEQQLDFLRTIRGLENVEMVQPGYGVEYDHIDP-RELKHTLETKRISGLFLAGQINGTTGYEEAAAQGVLAGINAGRLSRADGFIGVMVDDLVTKGVNEPYRMFTSRSEYRVSLRADNADLRLTEKGGIVGDA-RSAFELLERVGIAGKYFLRDENLAIDESVDYDTMRPATLGQAKRLEGVTPASLASLMK Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 TQVVVIGAGHAGCEAAAASSRTGAHTTLITTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDH-PNLSLLQNKVADLLDDGTQVGADQVIITTGTFLSAEIHIGDKRIA-AGRIGEGISNTLV-GFQLGRLKTGTPARLAKESIDFSQKGDALPVPMSFLN-QLD-CFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDP-RQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGGIISPV-RSAWEIFTKINIQGKYFQADENMLLPQDYDYRQLQPLTIGQARRIQGITAAALFELYR Salro YDVVVIGGGHAGCEAAAASARVGARTVLVTDTIGT-----------------------------------------------------------------------------------------------------------------QRIP-AGRKGERLAQVLC-QFRMGRLRTGTPPRLHVDSIDFSQKSEYPPVPFSFLT-LVS-CHMTYTNAEAHAIVHETLHENCHIQE-EVTGPRYCPSIESKVLRFTDRDQHQVWLEPEGLNSEVIYPNGISMTMPEEAQQRFIRLMPGLQNATIVQPGYGVAYDYIDP-RELQHTLETKKVAGLFLAGQINGTTGYEEAASQGIIAGVNAASLDRAQAYIGVLIDDLVTNGVSEPYRMFTSRAEYRMTIRADNADVRLTELGGCVSED-RSALDLVERIFIEALYYRKEEQLVLPEDLDYDKVRPATLGAASRLRGVSAASCITLLT Schco3 YDVCVIGGGHAGCEAAAGAARTGARTILLTATIGEMSCNPSIGGVGKGTLVREVDALGGLMGRVADKAGIQFRILNRSKGMALWSPRAQMDRVLYRTNMQGTLNNY-PNLDVRAGSVFDLLDSGDIIPCSQVVICTGTFLGGEIHIGLKRFP-AGRMGEGLSASLA-GFKLGRLQTGTPARLAKDSIDFSQLGDDPPSPFSFLH-RIS-CFMTRTTSETHQIIRDNLHRSVHIQE-TRKGPRYCPSLEAKILRFASKTSHNVWLEPEGYDSDLIYPNGISNSMPEDVQEAFVRTIPGLENAKIVRPAYGVEYDFIDP-RELGASLETKRIGGLFLAGQINGTTGYEEAAAQGIVAGINAGLISRADGFIGVMIDDLIVKGAEEPYRMFTSRSEYRMTIRSDNADMRLTPLGGVVDDA-RSGWDLLARVDIDGRYFLQDESFTLDPQMDYDAVRPATIGAARRMEGITPISIVLLMR Schpo1 -NVVVIGGGHAGVEAAAAASRLGAKTTLLTDNIGQMSCNPAFGGIGKGTLMREIDALGGVVSGVCDESAIQFHMLNRSNGPAVWSPRAQMDRSVFKKNMQKTISTYRKNLQVREGAAVSILEDGTAIPASCIVITTGTFLGGQINVGLTQLA-AGRYGEPLSKCLL-GFKMGRLKTGTPPRLS-SPINISQTGDEIPETFSFLN-QRS-CYRTYTTELTHEIVRKNLAFAPHMLAGDILSPRYCPSLEAKVTRFPHKARHLIWLEPEGLDNSWWYPNGLSNSMPEEIQHNIIRSIPGLENCNIVRPAYGVMYDYVIP-TQLKATLETKKIQGLYLAGQINGTTGYEEAAAQGILAGLNAGLIPRNTALLGVMVDDLITKGVKEPYRVFTSRSEYRLTTRADNADLRLTPLAGLLDDQTHSAWDLLQRLIIEGKYNCRDESTVIPSDFDFDTLRPATIGQLKRIQGIKPGTIIRLLR Sorma FDVVVIGGGHAGSEACAAAARAGARTALVTENLGVCSCNPSFGGIGKGIMIREIDALEGLAGRIIDKAGVQFRVLNSKKGPAVWGPRAQIDRALYKKHMRAELESY-PNLSLVYNSVSDILESGEVLPTSQVIITTGTFLGGEIHIGMEAYP-SGRMGEGLSKSLA-GFKLGRLKTGTPPRLDKKSINFGQYGDDPPRPFSYLN-QLH-CWATYTNHATHEIVRQNLDKTIHIRE-TVKGPRYCPSLEAKIIRFSDKQRHLVWLEPEGFDNDIIYPNGLSMTVPAEAQLALLRTIPGLEDVIMTQPGYGVEYDYVDP-RSLKRTLETKAIRGLWLAGQINGTTGYEEAAGQGIVAGINAGRLSRADGYIGVMIDDLITKGVSEPYRMFTSRSEFRMTTRSDNADSRLTALGGVVGDR-RSAFELLERTFIEGLYLEREEDLRLPLDLDYDAIRPESLAQARRIEGMTPAGCMRLLA Sphar -----------------------------------MSCNPAFGGIGKGTLIREIDALGGVCGRVCDEAGIHFRILNRRKGAAVQGPRAQIDRDIYRKGVQKELLTT-PNLDIIAVGVDDLLADGSRVSSKAVILSTGTFLRGMINIGEKSYE-AGRLGDGLATCLL-RFNMGRLRTGTPPRLDGKTIDFSQPGDDEPIPFSYLN-QVQ-CYMTHTNEEGHQIARDTLHMNRHVTG-ESKGPRYCPSIESKVLRF-DRPRHQIWLEPEGLSSELIYPNGISMTMPEEAQERFIHTIVGLENAKVVRPGYGVEYDYVDP-RQLYPWLETKLVGGLYLAGQINGTTGYEEAAAQGIIAGINAGLVDRSEAFIGVLIDDLVSQGVSEPYRMFTSRAEYRLHLRADNADLRLTEKVGVVCDE-RSAFDMLERMDIEGSYFKKDEHLAIPHNFDFLSLQPLSLGAASRIPGITPTHLIQMLK Spipu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 YDTLVIGGGHAGCEAAAASARAGAKTLLITDTIGEMSCNPSFGGIGKGTLVREIDALDGLCGRICDKAGIQFHVLNKSKGPAVHGYRAQIDRKLYKREMQHTLASY-PNLEIRKASVEDVIDDGHVIPCKSIVISTGTFLGGETHIGMVTTP-FGRIGESLSKSLA-GFELGRLKTGTPPRLRKDSIRFEQEGDMPAKPFSFLT-QVH-CYQTATNVASHEIVKANIHKSVHVRE-TVKGPRYCPSIESKVLRFGDKLSHTVWLEPEGYDSNLIYPNGISITLPAENQLELLKTIPGLENVDMVQPGYGVEYDHIDP-RELKHTLETKRIGGLFLAGQINGTTGYEEAAAQGVLAGINAGRLSRADGFIGVLVDDLVTKGVNEPYRMFTSRSEYRVSLRADNADLRLTEKGGVVHDQ-RSAFDLLERIGIAGKYFERDENLSIDSRVDYDTLRPETLGQAKRLEGVTPASLATLMK Stehi1 YDVCVIGGGHAGCEAAAGAARTGARTVLITDTIGEMSCNPSIGGVGKGTLVREIDAMDGLMGKVADKAGIQFQILNRSKGAAVWGPRAQMDRKLYKSHMQHALHNYGPNLSIRTGSVYDLLDTGEIIHCSQIVICTGTFLSGEIHIGSRRIP-AGRINDGLSHTLAFALPLSRLQTGTPARLDGKTINFEMKGDEKPKSFGFLT-QVV-TWQTFTTPETHKFVRDNLHLSVHIQE-TKKGPRYCPSLEAKITRFAAKNEHTVWLEPEGYDSDVIYPNGLSNSMPEELQETMLRTVPGLENVKMVRPAYGVEYDFVDP-RELDSTLEVKRVQGLFLAGQINGTTGYEEAAAQGIVAGINAGLVSRAEGYVGVMIDDLVMKGAEEPYRMFTTRAEYRMTLRSDNADLRLTAKAGAVSDT-RSAFDMLERVDIDGRYFTDEESLLLSPRMDYSVVRPRNIGQAKRMEGMTPKGIVMLLR Tapde11 FDVVCIGGGHAGCEAAAAAARTGARTALVTESIGEMSCNPSFGGIGKGTLLREIDALDGLCARICDEAGIQFRILNRSKGPAVWGPRAQIDRKLYKRNMQAMIHNY-QNLSVIGGAISDLLESGEVIMAKTVVITTGTFLGGEIHLGLEAYP-SGRMGEGLSASLA-GFKTGRLKTGTPPRLLKSTINYDQHGDDPAAPFSFLN-QVP-CHQTMTTPSTHDIVRQNLDKSIHIRE-TVSGPRYCPSIESKIVRFQQKDNHTIWLEPEGLDSDLVYPNGISMTLPADIQEQMLKTIPGLENARMTSPGYGVEYDYLDP-RGLYSTLETKLIPGLYLAGQINGTTGYEEAAAQGILAGANAGLISRADAFIGVLVDDLTTKGVDEPYRMFTSRSEYRLSVRSDNADLRLTELGGLVGDE-RTAFSLLARLDIEGSYLLADEALSLPRDMSYDDIRPETLGKAGRIQGVDPTALVIIMR Thetr -------------EAAAAAARVGASAVIVSADLGVMSCNPSIGGIGKGALVREIDALDGIMGLAADHGGVQFKVLNASKGPAVHGPRAQMDRDRYKEGVWRVLAEYAERLRIVEASAEDILGDGSVIAAPTVVLATGTFLRGVVHIGGESRP-AGRAQEGLAHTLL-ALPLARLKTGTPPRLAANSIVTDQVGDEPPVPFSFLS-AIK-CYMTHTNAATHAVVAGAMELSPVSGEGAGVGPRYCPSLEAKVDRFPDKAAHQVWLEPEGIDSDVVYPNGISNALPLEVQEKLVRTIAGLERADILVPGYGVEYDYVNPAKALTPWLETRLVAGLFLAGQINGTTGYEEAAAQGVIAGLNAGRLSRADAYVGVLIDDLITKGVTEPYRMLTSRAEFRLALRPDTADARLSRDGSSVRAA-RSLAAMLTRVGIRGRYMTAATGLRIPEWLEYETLRPATLAEAAAIEGVTPNGVHLLMR Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 FDVVVIGGGHAGAEACAAAARAGARTALVTDNLGTCSCNPSFGGIGKGTIIREIDALDGLAGRIIDKAGVQFHLLNRRKGPAVWGPRAQIDRDLYKKYMRSELESY-PNLSIVLESVSDILENGEILQTGRVVITTGTFLGGEIHIGLEAYP-AGRIGEGLSKSLA-GFQLGRLKTGTPPRLDKSTINFDQLGDNPPIPFSYLN-QLT-CSITYTNEASHKIVRDNLEKSIHIRE-TVKGPRYCPSLESKVIRFADKERHIVWLEPEGFDNPIIYPNGLSMTIPAEAQEQVLRSIQGLEQVKMLQPGYGVEYDYVDP-RGLKSTLETKAIGGLYLAGQINGTTGYEEAAGQGVIAGMNAGRLSRSDGYIGIMIDDLITKGVTEPYRMFTSRSEFRMAARADNADLRLTEKGGVVSDH-RTGIDMLDRVVIEAAYFVNDENIRLPLDLDYDSIRPETLAQARRAEGITPSGCIRLLA Umbra1 FDVVVIGGGHAGAEACAGAARAGARTLLITDTIGEMSCNPSFGGIGKGILMREIDAMDGLCSRVSDLSGIQFNVLNKSRGPAVHGPRAQIDRKIYKRHMQHILKDY-PNLTILSGSVHDLLEDGNTITASKVVITTGTFLGGEIHLGLKVWP-AGRIDEGLSNSLA-GFQLARLKTGTPPRLDGKTIDYSQNGDNPPTPFSYLH-QVQ-CHQTRTNSDTHKIIADNFHQSIHIRE-TVKGPRYCPSIESKIQRFTQKESHIIWLEPEGFDTDLVYPNGISNTMPEDIQLKFLRTIKGLENVDMVRPAYGVEYDYVDP-RELRSTLETKRIKGLYLAGQINGTTGYEEAAAQGIIAGVNAGLLDRADGYIGVLIDDLITKGVEEPYRVFTARAEYRLLLRADNADTRLTEKAGIVSKE-RSALDLLKRVEIEGLYLRRDEDILLDVNMDYSGLRPETLGAAKRIEGMTPAAVFVLLK Ustma22 FDVVIVGAGHAGCEAAAGSARTGARTLLVTHSIGELSCNPSLGGVGKGTLVREVDALGGLCGIIGDRAGIQFRMLNKSKGPAVHGPRAQIDRSLYRQHMQEALRQY-PNLTISEAKVHGLTTNGDSISCSQVILATGTFLSADIHLGLESRS-AGRMLPGLSQSLA-GFKLGRLKTGTPARIAASSVRLGIHGDAAPAAFSFLH-QVE-CWGTHTTPLTHEIVRQNLDKSIHIKE-TVRGPRYCPSIESKVIRFKEKQAHPVWLEPEGLPGSVLYPNGLSCTLPSEQQVELLRSIPGLECAEMIRAGYGVEYDHVDP-RELRHSLETKRIEGLWLAGQINGTTGYEEAAAQGCVAGLNAGLIGRSGGYIGTMIDDLVMQGVEEPYRMFSSRSEYRMTLRADNADKRLTPLLAAVGEQ-RSGLDMLDRVEIEAKYFNKETQLRFPEGFNFGSVRPTSLAALKSIPGCTPSNYATLWR Walse1 YDVCVIGGGHAGSEAAAASARTGARTVLLTDTIGVMSCNPSLGGIGKGTLVREVDALDGIMGKIGDVSGCMYKMLNRSKGPAVYGPRAQIDRELYKSNIQNTLKNT-KCLDIQAGSVHDLLDNGQVIPCKQVVLCTGTFLDGEIHIGMKSIK-AGRKGDGLSESLA-GFALGRLKTGTPARLKRETINFSQEGDTSPEPFSFLN-QIK-CYQTHTTPVTHDIIRQNLHKTFHIRE-TIKGPRYCPSIEAKIIRFHTRDSHNIWLEPEGFDSDVIYPNGISTTLPEEDQEKMIRSIPGLEKAEMIMPGYGVEYDHIDA-RELSATLETKRIPGLYLAGQINGTTGYEEAGAQGILAGLNAGLLTRADGYIGVMVDDLITRGAQEPYRMFTARSEYRLTLRADNADTRLTQKGGAVSES-RSAYDMLERVTVEAMYFMSEETLSLDPNLDYDSVQPLSIGAAKRIEGITPSAIITLLR Zygro1 EGVVVVGAGHAGCEAATGSARTGAPTVLITNKIGTCSCNPSMGGVGKGTLLREVDALDGVAAKVTDLAGIQFKMLNRSRGAAVWGPRAQIDREIYLREMQNKLNNY-PNLRLWEGKVKDLLEDGSLLKSSKVVITTGTFLSAEIHIGLETFP-AGRMGEGISETLA-GFQLGRLKTGTPARLDGRTIDYTQYGDDPPHPMSLIN-QVL-CYGTYTNLGLHDYIRSNLHRAMHIRE-TIKGPRYCPSIEAKILRFSDKDSHRIWLEPEGLNTDVIYPNGISNSMPEDVQIQMMRMIPGLENVEILQPAYGVEYDYVDP-RQLRQTLETKLISGLYLAGQINGTTGYEEACAQGVVAGINAGLLSRSDAYIGVLIDDLITKGVEEPYRMFTSRSEFRVSVRADNADFRLTELGGVVGDD-RSAWELFVKVNVQGKYFQADENMVLPQNFDYSQLQPETIGQARRIQGITAASLFELYR [Cluster2630.fasta_al_trimmed; alignment length = 419] Allma1 MDRRATAMM----TSGFGKSTGAAESEAPQRDDDDLDGD-E---PLTNEVHMQG-HSRAVTALDVDPSGARCITGSLDYTIRMYDFAAMDANL-RAFKSLEPDSFLLAPHAPQVRLYD-RDGAMRHEYAKGDMYLRDLRNTDGHTGTVTAVRWRPGHKQTFATSSFDSTIRIWDVERKQAHVIVFK---H-GTKSPVSTLTYS-RDGNLAGGAEDGSIRI-WKAQGPYS-TA-AITSLAF-AWDQHTLLSRSMDETVKLWDLRNFKHPLHTQNAVFSPDDQRILAGWAAVRVAWHPKLHQILVGTARGTAVMYRPGYS-QRGVTLAPRVRTVED--EKASE-----GKRQREGTAKPMPERQTMGG-G------------SLFDEDPREAILKYADVAAKAPAYSATQESDEEEDAEDR Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MD-GFDAFKKFF-PSSFGKQEKKAQIDRTKRADSEDDSD-DD-DPVSHELLIKT-HERAVTTMTVDPAGARLITGSTDCTLKLHDFASMTPTTIRAFKSVDPSHVMVVSATPQPRILD-RDGDTLTEFVKGDMYLRDLHNTKGHIAEVTSGAWSPTDYNLCVTAGTDSTVRIWDANRSQKEVIVHKSRVA-GSRSKMTAVAWG-SPKQLVAAALDGSLLM-WGGNGPFT-RP-STSGLDI-SSDGRLVITKGGDDTIKLWDTRKFKQPITTSNIIFSPTSANVVTGS-LVTVLWHERLNQILTGSANATHVLYNPNMS-TKGAALAPKRRHIDDVVVGSNGPHYSSGLTASGRSRDP---RRATTP-------KSQPDERHIREEDPREALLKYAEKAEKTKAWKETQSDDE-EEQEPN Aurde31 MA-DDDMMG--I-S-GFGKAKQQHTFDKTRR--DENGDD-DDAPPITHELVLKD-HSKVLSAIAMEPSGARMVSGGHDYEVKMWDFGGMDERA-KPFKSFEPDMYLVVSATMQAKLYD-REGEEKGMFMKGDPYLRDMHHTAGHVAEMTSCAWHPYETQQFITSSADSTIRIWDVERKQKTVIVVKSKER-GARTKVTHCAYS-YDGGIGGACLDGALHM-WNSSSNFV-RP-NTGSIVF-SMDGRTVVTRGGDDTVKTWDLRAFKKPVATTNAIFSPDEKYIVTGSG-VKVYWHSKINQIVAGLSNGMSMLYSPLTS-VNGAKMPRKKVTIEDILTPGAQSALADKRKRERGKIDPRKLRRVSGP-GRGGRVGASA-TQHVVQEDPREALLKYADLADKTKAWRATQDVEEKDSDEER Batde5 MN-NADMMG--L-PSGFGKSSRRKVLSASQAKNNELQSD-SDLAPTTM-AALKD-HTKAVAALSLDPAASRMITAGRDCTVKLWDFYGMTTSM-KPFRTLEPDQFLVAAATSQLKVYD-RDGGFITEFPKGDPYIRDLRHTKGHVSALTNARWNPTMKNCCISASTDSTIRIWDLERRQKDVIYVKSRQP-GGRTSITAVCFS-NDGRIAGAGADGSLRI-WNSNGPFL-TP-IASSISF-AMDGHSLITRAMDNTLKLWDIRKFKEPVAVTNAVFSPNDRYIITGTSVVKIQWSGKLGQIFAGTSEGVQVLYDPVLS-RSGIKVKPKKLTVEDIINPGV----NTKR---KMLEQEAISRRVLTK-GKGGKIGTNM-TQGIMKEDPREAILKFADTAAAAPAYKVNQVYENDFEEDLE Botbo1 MA-DQDSMS--L-PMSFGKQTKKGKFDKSRRYSDEA--D-AEAEPISHEVTLKD-HSKVVSALTLDASGARILTGSHDYDCKMWDFGGMGVSH-KPFRSWEPDSFLVISGNSQAKLYD-RDGEEKATYIKGDPYIRDMKNTAGHVGELTSCAWHPKEANTFITSSMDSTIRIWDVERKQKSVIVVKSKER-GARTKVTSCAYS-SDGKIAGACFDGTLNL-WQSNSNFV-RP-SAGSVVF-SIDGKTLLSRGGDDTVKLWDTRSFRKPLLVQNAIFSPDEKHIVVGCSIVKVVWHSKINQILLGLSNGIRVLYSPTMS-QNGAKLARKKVTIEDILTPHALPMFRDKRKRDKDRFDARKTKRVSGP-GRGGRVGASA-TQHVVQEDVGCGFLCVRGVGNETPGTAGQQ----------- Botci1 MS-DDEPMRAFL-PASFGKKSKEAQIDRTRRSDDDDEED-SDSDPTSHELILKT-HERAVTTTTLDPSGSRLITGSSDCTLKFHDFASMTPTTLRSFKSVDPGTFLCISAHPQAKLMN-RDGDIIGEFVKGDMYLRDMNNTKGHISEITTGTWSPMDKNICVTAGTDSTLRIWDVNRCQKEVIVHKSKAS-GSRTRMTAVVWG-GPAQLVSAALDGSLVM-WGGNGPYA-RP-TTGGIDI-SPDGRMVVTRGGDNLIKLWDTRKFKTPIVTTNIKYSPNGANIITGS-LITVQWHPKLNQIVTGSANSVHVLYNPNTS-VRGAVDAPKKRHVDDIVTPGGVSNISAGLTASGRSRDP---RRLVTP-------KSQPDEKHINEEDPREALLKYAELAKTTNAWKDTQSDEED--EGPD Caeel MDDNTA-----L-QAMFAQTISNQSVSVSSKPEDSDDSDFDETEPAACEAKISH-GTQAISALRVEPPGVRFASGGLDYYVKLFDFQKMDMSM-RYDKELLPETLVVASGEAIIRLLD-RAGKQWSETVRGDQYIIDLNITKGHTATVNCVEFNPLNKNEFISCSDDGSLRLWNLDNKHRKVIKTKGAN--GKRVSPQVCTFS-PDGKIAAGCDDGSVQA-WKYGSQYV-NV-NITSIAF-SPDSKRLLSRGFDDTLKMWSLDNPKEPLLVTDCGFSPRAEVVFTGTSCHRIQWHPRLNQIIAGLSDGIHVYYDQTMS-QRGVMSPLKRNRASEVLSPLSLEMFQPYLRMQDNKLRPEFRKPINGK-SANGRVGGSL-HSYLAKTDVRASILKHAKDAEEDKAYRKTQEDQDDEELQPV Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ----MDIMG--F-A-SFGGSGATSSLASSSSDDDDNDDD-DDDDPVSHEITLVH-GKKPVSALALDPSGARLVTGGHDYLMQFWDFAGMDRSF-KSFKSVEPDMLAVVSTGPQLRTYD-RDGNYLLESVRGDMYLSDMGNTKGHTGTITGVAWSPREKSVFVSSSHDGSIRVWDVNTQHKDLIRIKNGH--GRKAYAACVSYS-PDGAIAAGVEDGSIQV-YKSSSPYL-RP-AISCVRV-SRDGKHLLSRGMDHTMKLFDLRKYNKPLQVTECGFSPDDRMVFTGTSVIGCLWHPRLNQIVAGCSTGAKVLYSPHFS-VRGATLAPRRADTADIYTPYALPMYREKRALIKARADPLKSKRVTGR-GADGRTGVETWTQQAAKEDPREAILRHAQAAADTKAYQKTQAGEGDASDLP- Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin MSSNSAVMG--F-G-GFGKKAKSAIFEETRRDSDESD-E-EEEEPATHEVSLKH-GTKPVSSLALDPSGARLVTGSHDFEMRFWDFAGMDRAL-QSFRHLTPEHILVVAANSQAKVFD-RDGYEVLECVKGDQYLNDMYNTKGHNSMLNGGYWNPKIKDEFLTCSNDGTIRTWLLKKKCQTIRKCKDKS--GRRAQPTCCCYS-RDGKLAAATNDGSISL-WDVKMK-V-HT-TTSSIRF-AHDNKTFCTRGGDDTVKLWDIRKIKHPVATTDCIFSPNEKLLMTGTSAIRCLWHPKLNQIMVGTADGVKILYDPERS-VRGAKLKRKKLNQSEIITPYSLPLYREKKQEEKDRKDPIKSHKLSGRGGAGGRLGSTL-ASFIMKSNPRDAILKHATAAESSHAYAKTQSEDEDS--EGK CocheC53 FS-ADEALQQYM-PSQFGKKDGSAQIERARRSDDDKDSD-DDSDPVSHELIIKT-HDRAVTTIALDPSGTRLVTGSNDCMLKLHDLSALTPSTIRAFKTVDPGQFLCITATSQPRLFS-RDGDLISEFVKGDMYLRDKHNTKGHTAEVTSGAWHPTNRDRFATAGTDSTVRIWDVNMKQEEVIVYKSRAA-GSMTRMTAIAWG-AAAELVSAALDGSLVM-WGGEGPYH-RP-TTSGIDI-STDGRLVVTRGGDDTIKLWDTRKFKTPLNTSNIQFAPNMQSIITGS-LVTVNWHPKLNQILTGSANGTTILFNPKLS-NAGALTKPKKRHVDDHDPSGNA-----GLTASGKSRDP---RRATTP-------KSTPDQKYVMEEDPREALLKYAPKEGETGAWEKTQDSEEERGKGEE Coere1 MA----ELNKYI-PKGFGKKKNKSKVDVAQYKSETTD-E-EDTSPVSYHVAMTG-HKKAVSTIAWDPSGDGLASGEHGANMMLWSFPSMDRSF-QSYRTVVPDLLLCATGDPRPTLFM-PDGRKVCEFKRGDMYVMDMRRTTGHVAALTSVDWCP-EGGKFVTAGADSTLRIWDCEQTQLQVIVAKTQMR-GRRVAVTACAYS-ADGRIASTQDDGGLSL-WPSSGPFI-RP-TTSAVQFIPGNSNHLVTRGGDSTVKLWDVRNLKTSLATANMAFDSDGRYLLVGAAVLSVTWHPRLNQIAAGLTTGIAVMYDAS-S-TRGAKLLQARQTSEPIITPHALPLFREKRRREKAREDPLFSQKIYGH-GKGGVIGVNE-TQHIMKDDPREALLRYAAVAESSPSYKDTQMSEEPE----- Conco1 FKSSSDDLNAFL-PTEFGKKKSEKKYENNLDSDDETD-E-DDYDPITNMAKLAS-GSKAISAMAIDPSGSRMITGDYAYDLKFYDFNGMDSTL-RPFKEIEPGHILLAPGNSQAKILD-RDGKEVEQCIKGDMYLRDLKLTMGHIGELTCCQWHPTDHYTYLTASEDGTVRVWEVERKQKSIIIIKSGPR-AQRSVVTAASFS-QDGKIAAASRDGALAL-WPSNGPFI-SP-STSHILF-SQMEHNLYTRGGDGTVKLWDIRNFKSPVLRTNLIFSPDEKLIVTGSSVIKSFWHPTLNQIATGSGDGLNLFYDPEHS-KKGALLQPRKIQVDEIITP------DDKRVKTKKRSDPVASQRVNGQ-GHGGRVGTNY-TNFMMKEDPREAILRHAKAAEEAPAYQQTQEEQEPKKERKT Conpu1 MA-NQDAMG--I-A-GFGKTQRKRRFDQAKRDTEQI--D-ASEPPITHEAILKE-HTKVISALAVEPSGARVLSGSHDYDCKLWDFGGMGTSP-RSFKTWEPQQVLVISGTIQAKIFD-RDGEEKAAFVKGDMYIRDMKNTSGHVGELTQCAWHPKDPQSFITSSADSTIRIWDVERKQKTVIVVKSKER-GARTKVLSCAYS-ADGRVSGACLDGALHV-WNMSSNFV-RP-DTGSVVF-SVDGHTVLTRGGDETVKLWDLRAFKKPLATTNAIFSPDEKYILTGCG-VKVLWHSKINQIVAGLSNGISVLYSPVTS-LNGAKLAPKKPTVEDIMTPHALPMFKEKRKREKDRMDPRKSRRVTGP-GRGGRVGASA-TQHIVQED----------------------P---------- Copci MD-ADEAMG--I-T-GFGKTSQKHRFDKTKREDEEAD-E-DDSPPITHEIVLKD-HTKVVSALALDPSGARIVTGAYDYDCKLWDFGGMTAEC-KPFKTWEATRFLVIPATTQPRLYD-RDGDEQAVFIKGDPYLRDMKNTSGHVAEVMSCAWHPKDPKTFITSSADSTIRIWDAERKQKTVIVVKSKDR-GGRTKVSVCGYS-RDGTIAGVCTDGAMHL-WESNSNFA-RP-RTGSMSF-SIDGRTLMTRGGDDTVKLWDIRAFKKPLAVTNAVFSPDDKYILTGVG-VRVAWHSKINQIITGLSNGVVVLYSPETS-LNGAKLPPRKANVEDILTPHALPMFRDKRKREKDRMDPRKSRRVTGP-GKGGRVGASA-TQHIVQIDPREALLKYAEAAEKTAAWKVNQPQEEKEDDIL- Croqu1 ------EFG--L-PFQFGKITKQTKISKTKRVNDDGE-R-PSSSPISHEVLMQD-HTKTVSSLSLDPSGARLVSGSYDYTCKLWDFGGMNSSF-KPFRSWEPDSFIVVTAANQPQLYD-RDGAQIAEYIKGDMYIRDMRHCAGHIAELTGCAWHPKDPKTFITSAADSTIRIWDVERKSKTVIVLKSKER-GTRTKITACAYS-PDGKIAAAGMDGTLNI-WATSSTFS-RP-NTSAIQF-AADSKTIVSRGGDDTVKLWDVRALKKPLAVTNIVFSPDNRFLLTGLAVVRVLWHPKINQIITGSSNGIHVLYSPELS-TRGATL---ARVKGPIITPHALAMYKTKRRRERERQDPVKTLKLTGP-GRGGRVGASA-TQHVVQEDPREALLRFAAEHEGTGAWEETMEEKEKEEEERK CryneH991 ------GFD--L-PMSFGKKSKAAKVENTKRVSD----D-EQEAPISHEIILKD-HTKVVSALAVDPSGARIATGSHDYDTKLWDFGGMDHRL-KPFKSFEAQQLLVISGTVQPKVFN-RNGEDEMEFNKGDVYLRDMKNTNGHTAEINAGAWHPTDKSIFLTCSNDSTLRIWDTSRKQKQVIVVKSKER-GARTKVTACAWS-SDGKIAGVCLDGTLHI-WDTSSNFA-RP-KTTGVTF-SRDGLRVATRGGDDTVKLWDIRSIRKPLAVTNLIFSPDDTQILTGTAVVRVLWHSRINQIFATLSTGVHVLYSPNSS-IHGALL---KTAPRDIYTPDALPMYQELHQKEKK----AKKMKVSGV-GRAGRLGASE-TQSFVHEDPREALLKYASKEEQ--------------KQEM- Crypa2 MS-DNEPMRAFL-PASFGKRSKEAQIDRSRRDDDDDDDD-DDS-PVSHELVLKT-HERTVTSVSLDPAGSRLATGSLDGTVKLHDFASMTPTTLRAFRSVDLGTFLCVSAHPQAKIVS-RDGDILTEFVKGDMYLRDMHNTKGHVSEVTTGTWHPTDRNLCVTAGTDSTLRIWDVNRSQKDVIVFKSKAA-GARTRMTAVAWG-APASLVAAALDGSLVL-YGGDGPFT-RP-TTGGVDI-SSDGRMVVTRGGDNTIKLWDTRKFKQPLVSTNIKYAPNSTSIITGS-LIVVDWHAKLNQIVTGSANGTHVLYNPTIS-QRGAVDAPKKRHIDDIVSPAALAQ---GVTATGRSLDP---RRQITP-------RSQPDEKHIEEEDPREALLKYADVAKKTNAWKETQSDEEQE-EGPD Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi FSKNEDSFG----GISFNITTKVNNNDNESHSDDDDDSD-DDSDPISHEVTIKG-HARTVSSISIDPSGSRMLSGSYDCKVKFWDFNGMDSSF-RSFREIEPDIFSALPYTTQIRIYD-RDGHFKNESVSGDRFIQDLYHTKGHVSTLTAQCWHPTERDELISSSIDGTIRVWDVNSKNKSVIKSKNQKG---RVGVSNCCFD-QRGDVTGGMSDGTIAQ-WDKRSTLL-KP-KVTSIQY-NRDCYSMISRGMDSTLRVWDLRNPLKPLVVTNTIFGSYDRVIVTGTSVVNCHWSTKLNQIFFGCSDSIRGFYDPTQS-VNGLKLAPRVKNVADIITPNTLPLFRQKEK-KSQKINPSKEQL-----------SNST-MKHLVSEDARESFLRVANKKEQ--------EQQKEEKK--- Dmel ETEAEDVMG--I-S-GFGRKAAKEQIEKARVDSDDDDYD-EDSDPYTHEVQMQH-GSRAVLALAGDPSGARLVSGSIDYDMCFWDFAGMDSSM-RSFRQLQPDMILVISGNAQAKVLD-RDGFEKLECCKGDQYISDMSRTKGHVAQLTSGCWHPFNREQFLTAALDGTLRIWQ--KSKEQLQVIKTRAQ-GGRTNAASCNFN-RDATIAAGCVDGSIQT-WDTRKMFV-NT-TITSIVF-SYMGQQLATRSNDETMKLWDLRQFKQPLHTTDCCFSPDDRLLVTGESVVKTLWHPKLNQLFVSCGNGIKCYYDEHRS-IRGAKLHRKRQPMEMIITPHALPLFRQRKRMEKARMDPVKSQRITS--GQGGRVGGTL-SSYVIRQDPREAILKYAKDAAEAPAYKQTQPADEPATEADK Enthi -----------M-------------------NSDSSDG--EDSSPCTNEILVDS-HKRTTTSISCEKNGNRFLSGGNDCKVQLFDFTIMDSRF-LPFRELQSQLFITGTSNVQIKLFD-RDGRFKMGSKKGDMYIVDLKKTFGHTSEVTQVQFSPNCENEFISTSVDGTLRIWDVTTSQKEVIKL------GKRSAGTSCNYN-SSGNLVCVTHDNVIDV-FDTKIPKT-HP--HTSVQW-YCNDTMMITRNFDNKIN---IKHLEVKCPT-NVIVSPDNRFIVYCND---IEWNDCINQIFVGDDTGIHIFFDDTLS-RNGCLSENLPQQIKDKQKPYHH-----KHKRQKENA-------LYKD-------EANESFNSTIQVDPRKALFK----------YNTDQESDEDE----- Falba ------MFK--L-P---------GVLSTESQPSGAEKSDDDDEDPLANVLALPA-GDKSVQCIVADGPGSRTLTGGFDREIRFWPLDPIPPSL-APRYVLNPALLAVAPAAVRARIIDVRQRGAVWTTPRGDMYIRDRAHTKGHVASITSIQWNPINREEFVTSSEDGTVRTWSMVRAQKRVIVLRASSVDGTRLAVAAIAWPNAPGEIFAGCQSGRAGILFDPRTRIV-APDAFSNTAS-GTGGESFLSSGQDDGWSMLD-PNIDGEASVAGLHHTPDLSTKLAATAQQLTLVVEHLKQRALASGDGDLALTRDMVTRCMGHLLAKEARARDELAEADKLASAKARLEACDAVNDATAAREEADR-EEAGRLRAAA-ARADAEEDGLESLRELASLGEQQPLLADAPADPPNSSMQKK Fomme1 MA-DMDAMG--I-S-GFGKTQKKSSFSRNKR--DEL--D-AEA-PISHELPMKD-HTKVISALAIDPSGARFVSGSHDYDCKLWDFGGMGATP-KPFKTWEPTKFLVISGTIQPKLFS-RDGEELATYVKGDVYIRDMKHTAGHVGEVLCSSWHPKDSSTFITCSADSTIRIWDADRRQKTVIVVKSKER-GARTKVTACAYS-HDAKIGGACVDGALHM-WKTNSNFV-RP-DTGSFVF-SVDGRTVMTRGGDDTVKLWDLRSFRKPLATTNAVFSPDEKYIITGSG-VKVLWHPKINQILVGQANGVSCLYSPEHS-LNGAKLAVRRPTVESIITPHALPMFRDKRKREKERLDPRKSKRVTGP-GKGGRVGASA-TQHVVQQDPREALLKYADVAEKTSAWRQNQ-EEEEEGEKEQ Fusgr1 MS-SDDPMRAFL-PTSFGKKSKEAQFDRSRRSDDSDSDD-SDD-PVSHELVLKT-HERAVTTVSLDPAGGRLATASTDCTVKLHDFASMTPTTLRAFRSVDPGVFLCVSAHPQAKIMS-RDGDIVTEFVKGDMYLRDMHNTKGHISEITTGTWHPTDKNLCITAGTDSTLRIWDVNRSQKDVIVFKSKAA-GSRTKMTAVAWG-SSAQLVASALDGSLVM-YSGNSPFS-RP-ATSGIDI-SSDGRMVVTRGGDDLIKLWDTRKFTKPLVTSNIKYAPNSTSIITGS-LITVDWHPKINQIITGSANATHVLYNPQMS-NKGAVDAPKKRHIDDIMVPGATG----GVTVSGRSKDP---RRQQTP-------KNAPDEKSIAEEDPREALLKYADKAQKIKAWSKTQSDEED---GPD Galma1 MS-DIDAMG--I-A-GFGKATQKARFDKNKRSEDE---D-DDLPPITHEITLKD-HTKVVSALALDPSGARIISGSYDYDSKLWDFGGMDMRC-KPFKSWEPSKFLCISGTTQAKIFD-RDGEEEATFVKGDPYIRDMKNTSGHVGELTSCAWHPKDPKLFITSSADSTIRIWDVERKQKTVIVVKSKER-GARTKVTACNYS-PDGNIGGACLDGALHM-WQTNSNFV-RP-NTGSVVF-SVDRQTVLTRGGDDTVKLWDLRSFKKPLAVTNAAFSPDDKYVITGAG-VKVAWHSKINQIVTGLSNGIVVLYSPVTS-LNGAKLPPRKVTIEDILTPHALPMFRDKRKREKERMDPKKSRRVTGP-GKGGRVGASA-TQHVVQVDPREALLKYAD--DKTKGKKARVAVDSETGDYVD Ganpr1 -------MT----PPG-------P-------SDSDLDSD-EDGEPVESEAALRH-HTKLVSALSIDPSGARFVTGSYDYNVNIHDFAGMDARL-RPFRSFEGDRFLMATTAFFPKLFD-RDGNMVEEFIKGDQYLVDPKRTKGHTAPLSSISWHPTDRNRFLTAAGDSTVRIWDVTRSHLEVIPLKSRRR-GTRTAVTAARFS-RDASIACIAQDGALRV-YSAKGPFV-NP-TTAGLLW-RADDKSIVTRGYDGMVKIWDLRATKGPVAASDVCLSPDERLIVVGTAVVRVTWHPRLNQVFCSTGGGVRVFYGKG-S-MRGALQAVRKKRV-DILTPAAT-----KRKREKDHATRLAVRKATGQ-GKAGKIGYSL-HEQLLKDDPREAFLRHAEEAEQAPAYSKTQEDEEHEEEGEK Gloin1 ----------ML-PTAFGVKKKTDAFSKTRRESEEGD-D-DEGEPISHEIKLND-HYRTVSAIALDPSGARLITGGYDYDVKFWDFAGMDSSL-RPFRTIRPDQFLIISGSAQAKIYD-RDGFEMEEYIKGDPYIRDMRRTNGHIAALTSGGWHPNDKQTFITASHDSTIRIWDAERKQKDVLVHKSKER-GGRSVVTATCYS-PDAKIAGAAQDGGLFL-WAAKGPYV-RP-STSSILW-SRDNSTLITRGGDDCIKVWDVRNFKNPVLQTNVIFSPDERMIITGTAVVRVLWHSRINQIITGNADGAHVFYDPNIS-VRGAKLESKKRAVDDIIAPHSLAIFRDKRKREKLRKDPVASHRVSGP-GKGGKIGSSL-TQHIMKEDPREALLKYAAISEDGNAYKKTQTGEEEEEEVV- Hisca1 MD-GFDTFKKFF-PSGFGKQDKSAQIDRTKRSKSESESE-SD-NPTSHELTFKT-HERAVTTITLDPSGSRMITGSTDCTIKLHDFASMTPTTLRAFKSVEPSQVLVISATPQAKIFD-RDGDMITEFVKGDMYLRDMRNTKGHISEITSGAWSPTDYNLCVTAGTDSTLRIWDVNRSQKEVIVHQSRVA-GSRTRMTAVAWA-TPLQLVASALDGSLVM-WSGDGPFL-RP-STSGLDI-SPDGRLVVTRGGDDTIKLWDTRKFKTPITTANIMFSPSGANIITGS-LISVLWHEKLNQIVAGSANGTHVLYNPSMS-HNGAVLAPKRWHVDD-ATGQIA---SGGLTASGRSRDP---RRNKTP-------QSQPDEKHIKEEDPREALLKYAEKAEKTKVWKETQSEEEDEERKPE Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MS-TMDAMG--I-S-GFGKETKKSRFDKSKRS-DQ---E-DDISPITHEISLKD-HTKVVSALSLDPSGARIVSGSHDYDCKLWDFGGMDMRC-KPFNTWEPTKFLVISGTCQAKLFD-RDGEEQTTYIKGDPYIRDMKNTAGHVGELTSCAWHPRDPKLFMTASADSTIRIWDVERKQKTVIVVKSKER-GARTKVTACGYS-SDGKIGGACLDGALHI-WQTSSNFV-RP-NTGSLVF-SVDGRTILTRGGDDTVKLWDLRSFKKPLATTNAIFSPDDKFVLTGAG-VKVVWHSKINQIVTGLSNGIVVLYSPETS-LNGAKLPPRKVTVEDILTPHALPMFRDKRKREKDRLDPRKSRRVTGP-GKGGRVGASA-TQHVVQVD---------------------------T----- Lenti61 MA-DMDAMG--I-A-GFGKKTKQKRFEKNKRSEDE---S-EEA-PISHELILKD-HTKVVSALTMDPSGARVLSGSHDYDCKLWDFGGMDWRC-KPFKTWEPQQFLVVSGTTQAKLYD-RDGEELATFIKGDQYIRDMKNTAGHVAELTACAWHPKDSQTFITSSVDSTIRIWDVERKQKTVIVVKSKER-GARTKVTTCAYS-PDGSIGGSCTDGALHM-WQTKSNFV-RP-STGSLVF-SVDGQTVLTRGGDDTVKLWDLRSFKKPLLVTNAIFSPDNRYIVTGAS-VKVYWHSKINQIVTGLSNGICVLYSPDMS-VNGAKLPPRKATIEDIITPHALPMFRDKRKREKERMDPRKSRRVTGP-GRGGRVGASA-TQHVVQEDPREALLKLAATADETAAWRANQ---EGEGEKKE Malgl1 ----MDAM---L-PAGFGKPNST--------TNDQRQTS-NEHEPLTRSIQLKG-HTKSVSAVAIDRSGARVATGSTDYDVKMWDFGGMSSDL-RPFKSFEPKNLLCLNAATQPRVYD-YDGHELAVYKKGDVFMRDMRHTTGHISDITCGAWHPIDDTQFMTGGTDSTVRLWDVNASQKTVIVVRSKDR-GTKTKVSAATFT-PDAQIIAAAQDGALYM-WSTKGQFS-RP-AATGLAI-SPDGSSLASRGADNTLKLWDLRMLRTPVAVTDVLYSPDGSQVLTGVAVVRVAWHPRLNQVFASTRDGVHVYYDEQAS-HLGALLRARTRTNPYILVPEESPVYKK---------NPKNARVLQGR-GKGGRIGRSA-MQPLMMEDPREALLKYADKAKNTSVYAKTQDDDTDHSDHRQ Mellp23 ------GFD--L-PFEFGKKVKQSKISKTKRSQEEAE-E-EEEEPISHEVELKD-HSKTISSVSLDPSGARIVSGSYDYFCKLWDFGGMNSSF-KPFRSWEPDSFLVITASNQPQLYD-RDGSQLAEYIKGDMYIRDMRHCSGHIAELTSCAWHPKDNKTFITSAADSTIRIWDVERKSKSVIVLKSKER-GTRTKITACTYS-PDGKIAAAGMDGTLNL-WATSSNFS-RP-NTSCLQF-SNDCKTIVSRGGDNTVKLWDVRAMKKALVVTNLCFSPDQKYILTGVSVVRVLWHPKINQILTGSSDGIHVLYSPTLS-SRGATL---ARVRGAIITPHALSMYKTKRKRERERQDPVKTLKLTGP-GKGGRVGASA-TQHVVQEDPREALLKFAAEHEGTGAWESTMEEAEKEEEERR Mnele LSNEASVMG--F-S-GFGKVGKQSKINENAASDDDMSSD-DDEVPISHEIKLYH-SSKAVSGLALDPAGARLVTGSQDFDVKFWDFNAMDSRF-QSFRTIQPDLLLLASGGPQAQVLD-RDGSQVYECRKGDQYIVDMTRTNGHVSALYNAVWHTRDRNIFMTSSSDCTVRFWDINKNQKTVIKLKGSD--GKKVSPTHAVFN-KDSSIAVATIDGSLSL-YPTKGPFV-RA-KTSCLKF-SIDGNRILSRGGDDTVKLWDLRNISKPVHSTDCWFSPDEKVVMTGTSVSKILWHPKLNQIVVGCSNGAKVYYSPNLS-SRGALL-PRRRQVKNVINPYSLPMYREKRRKDKGRKDPLKSAAAFGLDAHKTK-GCSL-SAFVSKEDPREVLLKYADVCEKAPAY----TEETLDEEPAA Monbr IINEANMMG----FAAFGTVTESELLAQRKRDDDEDDAD-HDSEPISHEIVLQH-GSRPVSALALEPNGARLVSGGYDYQLKFWDFAGMDAAL-APFRQILPVCVLVCTGRPQVKVID-RDGSEILETARGDMYIFDSAKTYGHVGLVNAGLWHPTERDRFVTASSDSTVRIWDIS--KKSLLAAKCRSRAGKRTGVNCIVMT-RDGRLVAGCEDGAIHV-FVCSKTMI-RP-KVTSLCL-ARDGDTLYSRSTDGTVKRWSLKALRRSEATTDIVLSPDERFVLTGTSVLRILWHLKINQIMVACADGVKVLFDPVKS-DRGAKMAPRKKDPLDALNPYTM-RWQDAARKAKQLKDPKAARITRNV-GVGGRTSSSI-SQLVAKQDPREALLKYAEKAEASKAYEKTQDDQDPQEKKPK Morel2 MD-DSDALRAFM-PTSFGKQKPANYTSATSADSEHKD-D-EDEEPISHEITLNE-HSKTISAMALDPAGARLVTGGYDFNVCFWDFAGMDTRF-RPFRSMEPDKILIISGEAKARIYD-RNGMEIADYQKGDPYIRDLRLTSGHVAALTSGAWHPYTKDRFITSSTDGSIRLWDVERKQADVIAYKTKER-GGRTAVTAVTYS-SDGRIAGAGADGTVSL-YPSNGPFL-RA-TTSSIIF-SRDSQRMVTRGGDDTVKLWDARNLKHPLSIVNVIFSPDERLILTGTGVVRVLWHDKLNQIVAGNADGARVYYDPDVS-NKGAKLTPKKRAVDDIITPHALRMFKEKRKLEKMRKDPKASHRLSGP-GKAGKVGTNM-THQALTEDPRAALLKYAEMTEKTPAYKKNQPDGDEHRELK- Mucci2 -----------M-PTSFGKQEQKTEYEKTKRSDDDDD-D-DDSDPTSHEIKLSD-HHRTVSALTLDPSGTRLVSGSYDYDMKFWDFAGMDRSF-KPFRTVQPDTILVISGSARAKIFD-RDGIEKAEFAKGDPYIRDLRHTDGHVGALTSGCWHPSDKQTFATSSQDGTIREWDVERKQKTTIVYKSRER-GGRSPCTALAYT-GDAKLAGAYQDGTLQI-WDTKGNHI-RP-ATSCILF-SRDNKTMVTRGGDDSVKLWDLRNAKKPVKTANVIFSPDEKLIITGTAVVKVLWHPRINQIMTGSADGVTVFYSPTHS-SRGAKLAAKKRAVDDILTPHALPMFKDKRRRDKLRKDPVASHRVSGH-GKGGRVSMNQ-QQAVIKEDPREALLKYADLAENSNVYKKTQEEEEETK---- Mydma MASEEDLMG--F-S-GFGAKKPPQKLNEAKRKDDDSD-S-DDSEPMSHEITLLH-GQKVVSAMALDPSGSRLATGSYDYEVKFWDFNSMDVSL-RPFRTLTPDRILVSTGNAQPQVLD-RDGHQVYECKKGDQYIVDMKNTKGHVSMVRNSCWDPRDKNHFISCGDDGTIRLWDINKKNTDVIRMKNKQ--SKKTGVTFCLFN-RDGKIVGSGQDGSIQG-WDTRRLFV-NT-STSCLCL-SSDEKSLISRGGDDTLKYWDLRNFQKPVAVTKCLFSPDEKLIVTGTSVVCTLWHVKLNQILVGLSDGVKVLFDPTRS-IKGATLKNKRIDPGEIINPITLKLYREKKIKAKQRADPIASHKLGLSHGVGGRMGMSL-TGFVIKANPREAILKHAKAAAEAPAYSKTQSDSDSEEDDNE Neucr2 MS-DSDPMRAYV-PLSFGKTSREAQIERARRSDDDDDDD-DDSDPVSHELVLKT-HERAVTSVSLDPAGGRLLTGSLDGTIKLHDFSAMTPTTLRAFRSVDPSHFLCVTAHPQAKIMS-RDGDILTEFVKGDMYLRDMHNTKGHVGEITTGTWHPSDPNLCVTAGSDSTLRIWDVNRSQKEVIVFKSKAA-GSRTRMTSVVWG-ASGQLVAAALDGSLVM-YSGNGPFT-RP-ATGGIDI-SADGRMVVTRGGDGLIKLWDTRKFKEPLVKTNIRYSPDSRSIITGS-IIVVEWHPKLNQIITGSANATRILFNPEKS-FRGAVEAPKKRHIDDIVTPGASPK---GGTG----SGT---RGQITP-------RSQPDEKHISEEDPREALLKYAEVAKKTKAWKETQSEGEEEGEGPD Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------IWDVNRSHKDIIVVKSKNR-GTKTRISSAVYN-ITATIGIGAQDGIIRI-YDPKNT-S-RP-SIGSLEF-SKDGRLLLSRATDDTLKLWDIRHISKPLFVSNAIFSPDEQYVLTGTSVVKLLWHQRINQILVGNGDGTYVLYDPEKS-INGAKLKPRKKKVDEIYTPHAI--YKEKRKRDKLRNDPIASHH--------------------------------------------------------- Pench1 MD-EFDAFNKFF-PSSFGKQAKSTQIDRSKRKDSEDNSD-EDSDPVSHELVLKS-HERAVTTMTVDPSGARLITGSTDCTLKLHDFASMTPSTLRAFKSVDPSYVLAVTATPQPRILS-RDGEILTEFAKGDMYLRDLHHTKGHVSEVTCGAWNPSDPNLCATAGTDSTIRIWDASRSQREVIVHKSRAA-GSRTKMTAIAWG-SPKQLVGAALDGSLCM-WSGKGPYT-RP-STSGLDI-SSDGRLVITRGGDDTIKLWDTRKFKTPVTTSNIQFSPSSANVITGS-LITVLWHEKLNQIMTGSANATHVLYNPTMS-TKGAATAPKRRHV-DVVVGSNGPHYSSGFTASGRSRDP---RRMQTP-------KNTPDEKHILEEDPREALLKYADKAEKTKAYKETQSDG--EEQGPE Phybl2 -------------------------------EDDEDD-D-DDDDPITHEIRLRD-HQRTVSALTLDPSGSRLITGGYDYEVKFWDFSGMDKSF-RPFRTLEPDSFLAITGSARAKLYD-RNGLELCEYMKGDPYIRDLRHTDGHVGALTGGAWHPTDRKTFITSSQDGTIRLWDVDRRQKAVIPYKSRER-GGRSSATAVSYS-HDGKIAGAFQDGTLNL-WDTSSSFL-RP-VTSSVVF-SRDGHTLVTRGGDDSVKLWDTRNIKKPVRTANVIFSPDERLILTGTSVVKVLWHPRINQIVTGSADGVSVFYSPTHS-VRGAKLEAKKRAVDDIITPHALPMFRDKRKREKLRRDPKVSHRVNGP-GKGGRVGLNE-QQAVIAEDPREALLRYADAAEKSNVYKSTQQEQESE----- Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 MA-DMDAMG--I-A-GFGKTTKKSRFDRNKRGDDNFDSD-SDLPPTTHEIVLKD-HTKVVSALALDPSGARVVSGSHDYDCKLWDFGGMDMRC-KPFKSWEPHRFLAVSGTTQAKLFD-RDGEEQATYIKGDPYIRDMRHTAGHVGELSACAWHPKDSETFITSSADSTIRIWDVERKQTTVIVVKSKER-GARTRVTTCGYS-PDGAIGGACVDGALHM-WQTRSNFV-RP-NTGSLVF-SVDGRTVLTRGGDDAVKLWDLRAFKKPLAVTNAVFSPDNKYVVTGMG-VKVLWHSKINQVLTGLANGICVLYSPMTS-LNGAKLPPRKRTVEDIITPHALPMFRDKRKREKERMDPKKSRRVTGP-GRGGRVGASA-TQHVVQED---------------------VTVNAATGSTVD Polpo LKKDDDSF-----GLKFNITTKVENIEQEQHSDSDSDSDSDDSEPITHVEEMKC-HDRAVSSITIEPSGSRMLTASFDCKVKFWDFNGMDQSL-RSFREVEPDRFIVLPYTTQMKLYD-RDGFSLSEFVSGDRYIQDLNHTKGHVSILTGCSWSPVAKDEIITSSIDSTIRVWDINKKNLTVIKSRGTKGQGARVGFTCCTHD-VRGDISGGCQDGSISS-WDKRAGMS-RP-KVSSIQY-AKDGISMVSRGLDHSLRFWDLRKLDRPLMVQNVVFGSHDRLVLTGTSAININWNARINQIFVGCSDGTRVFYDPTLS-EKGIRLAPRKKDPADIITPFSLPLFKEKSKFKKDHIKPETASP-----------GPNL-TQHLVKEDARESFLRKAKEMEE--------D---------- Pucgr2 IAVAGDEFG--L-PIQFGKIQAKNKISQTKRSDSEKQ-D-EDEPPTTHEVLLKD-HSKSVSALSLDPSGARLVSGSYDYACKLWDFGGMNSSF-KPFRSWEPDSFLVITAANQPQIYD-RDGAQIAEYMKGDMYIRDMRHCAGHIAELTSGAWHPKDAKTFITSSADSTIRIWDVERKSKGVIVLKSKER-GTRTKITACTYS-SDGKIAAAGLDGTLNI-WATNSNFT-RP-NTSSLHY-APDNKTLVSRGGDDTVKLWDVRALKTPLAVTNVTFSPDNQYILTGVSVVRVLWHPKINQIITGSSDGINVLYSPSLS-TRGATL---ARTRGPIITPHALAMFRNKRRRERERQDPVKTLKLTGP-GRGGRVGASA-TQHVVQEDPREALLKFAQEHEGTAAWEKTMQEADREDEERK Punst1 -M-DAEAMG--F-S-GFGKAQKKKRFDKTKR--DEFDGN-SDLPPTTHELVLKD-HTKVISALTLDPSGARVVSGSHDYDCKLWDFGGMDHRC-KPFKTWEPHQFLVVSATLQPKLYD-RDGEELATFIKGDPYIRDMKNTAGHVAEVTSCAWHPKDSNTFITSSADSTIRIWDVERKQKTVIVVKSKER-GARTKVMSCAYS-PEGNIAGACLDGALHL-WNTSSNFV-RP-NPGSVVF-SVDGRTILTRGGDDTVKLWDVRAFKKPLAVTNAIFSPDDKHVLTGAG-VRVVWHPKINQIVTGMANGICVLYSPQTS-LNGAKLPAKKATIEDIITPHALPMFREKRKLEKARMDPRKSRRVTGP-GRGGRVGASA-TQHVVQEDVRHAQLSLAARGSRASSW----ALLDEPGRKVR Rhior3 ------ALREFL-PTSFGKKEERKEFEKTKRQEDFAD-S-EDGEPVSHEIKLND-HFRAVSALTLDPAGTRLISGGYDYDIKFWDFAGMDRSF-KPFRTVQPDSFLVVAGNNRPKIFN-RDGFEKSEYAKGDPYIRDLRHTDGHVGALTSGTWHPNDRQSFSTSSQDGTIREWDVERKQKTTIVYKSRER-GGRSPCTALAYS-PDAKIAGAYQDGTLQF-WNTN-SLL-RP-ATSSILF-SKDNRTVVTRGGDDTVKVWDIRNAKKPVKVVNVIFSPDERLILT---VIKVLWHPRINQIITGSADGVSVYYSPTHS-QRGAKLAAKKRAIDDIITPHALPMFKESRKRNKLRNDPKASHRVNGP-GKGGRVNMNQ-QQAVIKEDPREALLKYADVAETSNVYKKTQEEEEDEESKD- Rhoto1 ------LTG--L-PLAFGKKAPPSRIDTTKRVEDGAE-A-GEASPVTHEVVMKD-HTKTVSALSVDPAGARVVSGSYDYDCKLWDFGGMNASF-KPFRTFEC-SLL---RSTQVKLYD-RDGAEICEFNKGDMYIRDLRNTDGHVAAVTAVAWHPKNHSLFLTASSDSTLRIWDRERKSKSVIVVKSKER-GGKTKVTACAWS-PDGKIAAACDDGAIHL-WAASSNFT-RP-NTSSIVF-SPDGKHLATRGGDGTLKLWNPKALKKPLAVTNAVFSPDSRYVLTGTAVVRVLWHPRINQILTGSADGIHVLYSPATA-VKGVTL-PKARAADDIIAPHSLPMFKEKRKREKERHDPQKTLKVVGP-GRGGRIGAAA-TQHVVQQDPREALLKYASADPNTKAWAATQPDPEEEEEDGK Rozal11 --------------MAFGKHNLETDEENTEEETNEDD-E-EEFEPISYQATLKQ-HSRLVNTIHIDPAGSRMVTGGLDHEMRLWDFNSMDDTF-RSFRTIKPDRILVASSCQSAKMCD-RDGHTICDYSKGDPYLRDKKNTKGHTHAIMAADWHPFDGNTFITSGMDSTVRIWDVEKSQKSIIVIKGKA--AKRPAVSAVAYK-NDASIASGSDDGTIRL-WNAKGPFV-VP--ITSLSF-SLDGNLLLSRSWDNTLKVWDMRNFNDPLFKTCAMFSPDNKLFMTGTSVVKLYWHKRLNQIFAGSSGGVAALYDKERS-HKGVLCTSKIESFVSVYAPNSLPLFKEKEKRAQERYNYAKSKRNEAK-TKGSKLGDAY-TQHLVQSDPRAALMKYAKMAEEAHAYKRTQEYTEFE----- Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro YRPEEEMMG----FGSFGRQGESEMLAKAKRDDDEEEGD-DDAAPISHEVTLKH-GSKPIVTFTLDPSGSRLITGSLDYEMRFWDFNSMDVRL-QSFRRVTPDCLIAATGSPLTKLYD-RDGSEMYESLRGDQYIYDKRRTHAHVAAVNCAWWHPRNRSLYITGSHDGTVRMWDMD-GKKSMHTGVCRNR-GKHVPVLSVHMN-REGTILAGCGDGTVHT-FHSSEKAV-RA-RVTCVRF-ATNGRKFISRSTDGTAKLWDVYRMSKPELVTECVFSPDERFVLTGTSVISVLWHLKINQIVVGCTDGIKVFFDPRKS-DKGAKLAPREEDPLDVM-----VAWGEKSRKDKERKDPLKSKKDRGV-GKGGRLTSSL-SQYIASEDPREAILRHAEAAEKARAYAKTQ---HPEEEEPK Schco3 MS-D-DAMG--I-S-GFGKASKKSRFDKNKREEEY---A-DDAPPITHEVILKD-HTKVVSALALDPSGARVLSGSHDYDCKLWDFGGMDLRC-KPFKSWEPQRFLVASGTMQARLFD-REGEELAAFIKGDPYIRDMKNTSGHVSEIYNVVWHPKEPNTFITSSADSTIRIWDTERKQKAVIVVKSKER-GARTKVTACCYS-PDGKIGGACYDGAIHI-WNANSNFV-RP-NICSMVF-SVDGRTVLTRGMDDTVKLWDTRDFKKPIATTNAIFSPDDKYVVTGAA-VKVVWHSKINQILVGLSSGIQVLYSPTTS-LNGAKLLPRKVTVEDILTPHALPMFRDKRKAEKDRQDPRKSRRITGP-GKGGRVGASA-TQHVVQEDPREALLKYAEAGAKTAAWSVNQPEEEDEEEK-- Schpo1 MDGTNN-----I-PLQFGKQAQTALIARFIRSSDSEDWDSEENEPGSHEIMFPG-HSKIVTTTTFDKNGSRFYTGSLDNTIHCWDLNGLSATNPHPFKIIDPNQILALYTHSQPILYD-RDGSLIVRFSKGDQYIRNMYNTKGHIAEITDGCWQPDSSQIFLTTGYDSTARIWDVNKSQLEVFVHVPEGSHTGRIPVTSCAWNPAKPDFATAVLDGSIQF-WQKGSRTK-RP-VISCLSF-SQDGNYLLSRGEDNALRVWDLRNSNKCVNEGNAIFSPTQKLILAGSTVSAVSWNEKINQVSLGSADGAYVLFSPNES-IRGVKDPPKSKHIDDTVHINSLGLVEERRRRNAVRKDPKLSRQ--------GRL-----EENSVDEDPREALLKYADVAKSTKMYSETQTEGDISEEGNP Sorma MS-DSDPLRAYV-PLSFGAASKEAQIERARRSDDDDDDD-D---PVSHELVLKT-HERAVTSVSLDPAGGRLLTGSLDGTVKLHDFSAMTPTTLRAFRSVDPGHFLCVTAHPQAKIMS-RDGDILTEFIKGDMYLRDMHNTKGHVGEIATGTWHPSDPNLCVTAGSDSTLRIWDVNRSQKEVIVFKSKAA-GSRTRMTSVAWG-ASAQLVAAALDGSLVM-YSGNGPFM-RP-STGGIDI-SADGRMVVTRGGDGLIKLWDTRKFKEPLVKTNIRYSPDSRSIITGS-LIVVNWHPKLNQIITGSANATRILFNPEKS-LRGAVEAPKKRHIDDIITPGASPK---GAGGRG-VGGT---RGQITP-------RSQPDEKHISEEDPREALLKYAEVANKTKAWKETQSEGEE--DGPD Sphar MSDSDDMMG----FKSFGGVQAKTKLKTSVDEEDRDDSDAEEGDPVTHEANIVH-GSKSVVSVSIDHSGARLLTGGVDYEVKMYDFNGMDMSM-SAFRTIEP------------------------ECVRGDRYISDTAHTKGHISYLHGGMWHPSIKNTYMTYGADGTIRLWNSETKQKTVIKMRGQQ--GRRACVTCAAFS-PNAAIAGTSDEGGLYL-WKGSGPFL-RP-TITHMRF-SKTSKQIATRGKDDCLRLWDVTNFRKCVNETQCEFSPDNSLIITGTSTISVLWHPRLNQIVVGCADGVKIFFSESGS-QKGAKLRKRIRQTGMIITPHALPMFRDQKQKDKMRLDPVKTQMFTEAHGVGGRVAPNL-TQHLVGQDPREAILKFADEAENSDSYKKNQVESEEESD--- Spipu1 MASEEEAMG--L-PVGFGAKPKDVAFEETRRANDDEDED-EDHEPLSHQAGLKD-HERTVCALSVDPSGARFVTGGRDCFVKLWDFHGMDASL-RPFRSFEADQILVASTSAQAKLYD-RDGIELEEYVKGDPYIRDMRHTKGHVAALTGCRWHPHDKATFLTSSLDSTIRIWDVARAQKQVISVKSKLP-GGKTAISSAAYS-PDAKIAGGASDGALRL-WNTNGPFL-KP-TMTSVCF-SLTNNLLATRAMDDTLKLWDIRKFTTAVASTNVVFSPNDRYILTGTSVVRVQWHGRINQILTGVGDGVQVLYDPLVS-LSGVKVRPKQRAADDILTPHALPMFRDKRRREKLRSDSVATRKLSGP-GRGGKLGTNL-TQHILKEDPREAILKHAKDAEEAPAYQKNQVYEDEDEAARA Sporo1 ------MTG--L-PLAFGKPVQDAKIQQTKRGHDQDQ-L-APSSPITHEVVLKD-HLKTVSALSMDPSGARLVSGSYDYDVKIWDFGGMKSDF-KPFRSFESDSFLVANGSDQVKYYD-RDGAEIGEFVKGDMYIRDLRHTSGHISSISSISWHPTNPSLFLTASSDSTLRIWDKTRQSKSVIVVKSKER-GGKTRVTSCCWSKPDGKIAAANEDGSLMV-WKSSSNFT-RP-DTSSIVF-SPDGKYLGTRGGDGTVKLWNPKNLKKPLSTTSLTFSPDGKYLLTGTAVVKVVWHPKINQIVCSTSSGIHVLYSPELS-QKGALLKPTVESTFSIIAPHSLPMFKDKRKRERERHDPQKTLKITGP-GRGGRVGASA-TQHVVQQDPREALLKYATTDPATSAWSKSQSDSDDDKERPK Stehi1 ----MDAMG--I-A-GFGKKTSKGRFDKNKRSDDE---D-DVGPPTTHELVLKD-HTKVVSSLALDPSGARVLSGSHDYDCKLWDFGGMDARC-RPFKSWEPHKFLVISGTSQAKLYD-RDGDEQATYIKGDPYIRDMKNTAGHVGELSACAWHPKDAQTFITSSADSTIRIWDVERKQKTVIVVKSKER-GARTKVTTCGYS-PDGRIGGACIDGALHL-WKTNSNLV-RP-DTGSLVF-SVDGRTLLTRGGDDTVKLWDLRAFKKPLATTNAIFSPDNKYVVTGAG-VVVQWHPKINQIITGLTNGISVLYSPSSS-LNGAKLPSKKPTIEDIITPHALPMFREKRRREKERMDPRKSRRVTGP-GKGGRVGASA-TQHVVQEDPREALLKYAERAEQTAAWRANQEEDEEEGS--- Tapde11 ME-DQEELQKFLGTTSFGARNAKAAYARTKRSESDEDSL-EDS-PISHEILLEK-HTRAVSGLALDRSGSRIVSGSYDNLVAFWDFAGMNSSS-RAFKILEPELLLLTAANWQPKIVS-REGEEIGEMPRGDPYLRDMKNTKGHVGEVTSGAWHPTNAVQCVTSASDATIRIWDASSKCLQVLVHKPKKA-G-KVKCTVSKFS-PDGKIGSAFVDGTLSL-WATDGPHH-RPMATTDITF-SLNGYAFASR-GSNCVKLWDRRNFKVPTAITSLVYSPNNQELLTAT-AIRVIYHSQLNQIITSHADGIHVLYSPDKS-VRGAKLAPKSRHIDD-VRPDEAQL---A------RKDP---RLEL-P-------ARYAERKVIGDQDPQKELLKYDAAAKKFGIYEQNQEESAQGADSPA Thetr ------MIG--P-P-----------------SDSDSDSDSDSSD-MVSALAAPT-S--------AD----RLWSGAIDGSVRVYDFGLLGAGL-SSMRV---SRLAASTI--------------------GDPYIRDQRMTTGHTGSICNAVF--VSSTRVLSGSMDGTVRLWDASSNARQTLVMRTKSTTGTRTAVSAT---NADGT-FAGCADGSLQV-FDPRANLT-KPTAITSMLV-SADDRLFVARAQDDSLRIWDGRKVDRPIKVAGLAFSP-------------ILYPEPLKQMFVGMGDGLLALYDEQIS-CGG------------------VAPVRD-------VVDPTAG--LAGK-GHSGKLGISH-ARAVIEQDPQEALRK----------YATAPAEP-------- Treme1 ------AFG--L-PMAFGKKAKTAKVATTKRGQDEGDEE-EDEEPISHEIVLKD-HTKVVTALAVDPPGARLATGSHDYDTKLWDFGGMDARL-KPFKSFEAQHLLIISGTVQPKIFS-RDGDEEIEFNKGDVYLRDMKNTQGHTAEINAGSYHPLDKTQFLTCSNDSTLRIWDVARKQKQVIVVKSKER-GARTRVTACGWS-HDGKVAGACLDGTLHI-WNTSSNFA-RS-NTTGLAF-ARDGHRITTRGGDDTVKL------------TNVIFSPDDRIVLTGTAVVRVLWHSRINQIFASLSTGVHVLYSPHSS-IHGALL---RTAPRDIYTPEALPMFADLHQKEKR----SKKFKVSGV-GRGGRVGGST-TQGFVQEDPREALLKYAEKKEK------------------- Trire2 MD-SDDAMRAFL-PASFGKQSKEAQIERSRRDSDNDSDD-SDD-PVSHEIVLKT-QERAVTSVSLDPAGGRLASGSLDCTIKLHDFASMTPTTLRAFRSIDPSAMLCVCAHPQARILS-RDGDILAEFVKGDMYLRDMHNTKGHISEITTGTWHPTDKNLCVTAGTDSTLRIWDINRSQKDVIVFKSKAA-GSRTKMTAVAWK-NSAQLIGAALDGSLVM-YSGNGPFT-RP-ATSGIDI-SSDGRMVVTRGGDDLIKLWDIRKFDKPLVTSNIRYSPNSTSIITGS-LIAVDWHPKINQIVTGSANATHVLFNPSMS-SRGAVEAPKKRHIDDIVTPGAMG----GVTGTGKSKDP---RRLQTP-------KSQPDERHIAEEDPREALLKYADKAQSTKAWTKTQSDDED--EGPE Umbra1 MSWNDDALRSFM-PTSFGKQEKKSFFEKTKRIDDDDDSD-DDSDPISHEIQLKD-HHRTVSALALEPSGSRLISGAYDYDVKFWDFAGMDASY-KPFRTIEPDSFLIISGSARAKLFD-RDGYEITEYAKGDPYIRDLRKTDGHISSLTSGAWHPHEKNTFITASQDSTIRIWDVERKQKDVIMYKSKER-GGRTIVTATAYS-KDGKIAGACQDGTLNV-WASNGPFT-RA-VTSSVVF-SMDNQTFVTRGGDDTVKVWDLRNFKKPVSVTNVIFSPDERLILTGTAVVRVLWHAKINQIITGSADGIGVYYSPTAS-VRGAKLEPKKRAVDDIITPHALPMFKEKRKREKLRNDPKASRRMSGP-GRGGRVGTNT-QQHVIKEDPREALLKYAAVSEDGKAYQKTQEDDDEDDDE-- Ustma22 MD----ALRAMM-PISFGKRRAQASVNAEGLSDDSDDSDDQDSDPITQTATLSGIHAKTLSALAVDASGSRFALGSYDSYLSLYDFGGMTSSL-EPFRHFEPSHLLVISATREAKVFT-RDAAEIGTCRKGDPYLRDMRRTSGHVSALTCGMFDSHELAKFYTGASDGTVRIWSEERAQHDMIVLKSKSR-GTRTKVTAIACE-----IWASGEDGALRM-WDLRENLNGRP-RTSCI---ATSGETVVTRGGDATVKVWDARKPTRPVVETGVILDPNSRSLITGVS-VRLHWSSHTDQLFATHRNGLSILYNPTRS-TNGITLRPQSPTADSSTAPSES-----RRRLARARQDPHQTLLLHGP-GKAGRIGAGV-QQSSVQIDPREALLKYANRTAH------------------- Walse1 ------MMG--F-S-GFGKKKTEERLDNTKRNEGDKD-D-EDEEPSSHEVVLQD-HSKAATAIDLDPAGSRLASGSHDYDIKLWDFAAMNTAF-RPFRSFEGDSILAASGQAIPRLFT-RDGDEIYKWSKGDQYIKDQRQTKGHIGEINNCAWHPFDYNLFITCSADSTVRIWDVTREQKHVLVFKSKER-GTKTKVTACAYS-PDGKIVAVGYDGAMHL-WSTAGNYA-RP-NTSSVCF-TPDSKYIVTRGGDDTVKLWDVKNIKRPVHVVNATFSPDGKYVLTGVAVIRTLWHSRINQIIATHSDGIYVLYDPMSS-IRGALMPKRARDVEDIITPDAM----EKRMRMKKESD---ARKLVGS-GRGGRVGASA-TQAMVQQDPREELLKYADV-DNTGAWKESGTEEQMKERKRK Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2639.fasta_al_trimmed; alignment length = 147] Allma1 DALPYVDTQYTI-PEVKTLVDQMIDAELRTARTSQIDLDAYNLEEWLAAVQRASTLLQHQATRLENLELLGVYGSNAWLYHLHQMEAAVKAAEGALARAQAAVTRVNRERKTEQTEALDKLQRAHL-------QLLETRTSAVAQLE Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 DSLPYIDAEPS--AQARAAAQQLIAAELSPDRKAAIDLSRYEADAWRRILQRAYMASSHLSMRHENLALLEEYGKNAWLIGNSQLEDILRGLEKELAETKEAAEAVNKQRKLAQEASQGEMVSLEETWKRGVSAILDVELAQILEQR Aurde31 DSLPYFDRDLELFPDLRRKVDAELAREAAKARIEAIDTSRYSLDEWRAAADNAKAQLTHQRLRQSNLALLQTYGANAWRIHNYLLEADTKVYDEALEKLKEETVELNRERKNYQTRAGAQLSALETRWTELMSNLLQIEVAEIEGLK Batde5 DCLPYIDPDYD-----PAIVDALVNAELQSDQVAAIDTTRFRLNEWDAAVNNARAQLEHQSQRLVNLELVTRMGANAWRIHNYQLEAAIKNMKSQLELCNERIEAVNKIRKADQMQAQPTLRALSERWTELIQSTIAVRMEQIKQLQ Botbo1 DSLPYYDRDLELHPSLRALVDAEIARELKRVRVQSLDSSRYQLADWKAAVQNAKAQLQHQQSRETNLSLLQTYGANAWKIHNYLLESEATRLDKALEELKEQVTTVNRDRKNFQTHVGKQLTAMETRWTELISTVLQIELAQVEQLR Botci1 ESLPYIDVEPT--PSERAAAESLIASSLEPARISSIDLTRYETLPAQTLLSQAYTSQTYLNTRLTNLSLLDQFGKNAWLIGNAQLEDILKGLEREVAAKKDEIDVVVIGRKNAQEAAEAEIKGLEEGWKKGIGRVLETEVAEILDRR Caeel DALPYLDTEYN--EADRQLAMKLVEHECKTDRMKKLDMSRCELKLWAKVLRNAKAQNEHLLMRQINLELMDEYAAESYLQRNKVMEDLLTHAEKELRKTKEAVMEVHANRKMAQLKAGEKVKQLEQSWVSMVTNNYRMEMEQIKALK Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------- Capow DVMPYAEQDLQD-EQASANVLALIQAEMATARVAAIDMSRYEFAAWKACIDQARMLIEYQHTRLLNLDLLAKHGPAAWRLNAEIVAHLHTQLTNLLNEAQDEIQEVNRERKDQQTKLYNKLYELESTWYSLVGKNMQLEQEELARRE Catan2 DALPYIDNQYKL-PAVKSQVDALISSNLPSVHSTNIDLAAYSLAHWRALVTRAATLHAHLTNQMQNLELLGVYGANAWRYHLMQVEAHVEALEKHVKAVAEQVAQVNEVRKAEQENAGQQLDRASI-------ELLRTRMSTVAHME Cioin DALPYFDKGYDD-PGVREAATAMVEEETRRERLEALSMRRYDLTAWEECVKNSHAQLQHQDVRIENLNLMLEHGSNAWRLYNEQLVAMLQDAQKQLQSIKKDIQDVNWERKSEQTKAGEKLRTLEANWVNLVSKNYEIEEAL----- CocheC53 DDLPYVDTQLD--ANSIAAAKAAIDADIRSARLDDIDLKRYEDERWSKALKQAYTSSEYVQGRLTQLSLLEKFGKNAWLVGNSQLEDILKSIEAELASLKKQQEETDMARRAQQDSVSGEIKTLEETWKKGLGRLLETEVAQIMDKR Coere1 DSLPYIDKEYDD-PIAREQVLGLIQEEMERERVRAFDVERYKLDAWKRAADNAASQLEHQGMRMENLELLQNFGANAWKLSNYQKESLLASIENATRRYEEEGTHLNKERKYEQTEAGIKLRDLEERWNEGVRQCIEIQVAEIEALE Conco1 DALPYADKELKD-AKLQEQAELLIEQEMNLSRIKALSLDKYQK------ADEVNTMVEHQTVRNINLNLLEKYGINTWTVNHFQLEKLSSNLETELSYLKEQTLGLHKQRKAFHLDQGRRIEQLKKKFKDSINTNLQLELA------ Conpu1 DSLPYYDNDLEQYPILHEKVKRELAREPKPDRVESLDTIRYQLEEWQQALDNAQAQLEHQRIRQTNLALLQQYGSNAWRIHNYQLEEMAKQTEKALEELKGVTTDLNRERKNSQTRIGAQLTSLETRWTELISSILQIEMAEVDRLN Copci DSLPYYDDDLQKYPNLKSKVDQELARELKADRVKALDTLRYQLEEWKAALNNARAQLQHQRIRQTNGTLLQTYGANAWRIQNYLLESTVKQVESLAEELKQKTVEVNRERKNDQERLGKQLTSLETRWTELISNILQIEMAEIDRLN Croqu1 DSLPYYDRDLDIVPNLRQRVEREIEKELKTEQWGILDLERLNIKGWQQSFNNSKAQLEQQRLRLLNLNLINQFGSNHWKLYNFLIEKEISKLTLILDDFTNQIDRVNRRRKANQTDVGDQLNDLSQKWQNLISNNISIEIMEIKSLK CryneH991 DALPYVDKQVED-PINKAAAQALVEAELRH----PIDPSKY--EELEAAEKQGRIGEGYMGLRLENTSILSSYGPNAWLVRNYQLNSQLTELQATLATLKEQVTDINRTRRVFQEETGQHLSRLEGRWQDLVGSTVQLELAEVKGLE Crypa2 ESLPYIDQEPT--PAERAAAEALIAME-RSDRIAAIDLSRYEA--LEPALSQAYTAMSYLTSRRQHLALLDTHGKNAWLVGNWQLESELRAVERELAATRREIDLLTVRRQRVQAEAAGEVRGLDEAWRRGVGRVLEAEVAEVLERE Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi DSLPYVDDSVN--ENEQELINKLISDEMSTKRMEKFDIGRYKVKQWNDSLNNARSQLEHQDIRKINLELLQRYGGNSWKLYLSDLEILQKTLKKQLDQKKQQIEEINIQRKLSQEQTFEKIQQHDKKFLELVYKNTEIESAEIEQLK Dmel DALPYIDHGYDD-VGVRESALAMVEEECRRERIQNLSMKRYELSAWQEAIENSMAQLEHQWVRSLNLELMLDYGTEAWKSYLEVFTAMQAKAQLQLQQLKKDIQDVNWQRKQAQTQAGERLRSLEAHWVLLVSKNYEIETEIVHAAR Enthi --------------------------------------------------------------------------------------------------------------------------------------------------- Falba DALPYAEGDALQ-PQERAAVRRQIEAAMR-ERIRRLDRTRLQLACWERAVRNAEAQLSHQHIRISNLELLQKFGADAWPAHLFNMQALLDRRNAELSRSRSSIASTNRARRFLHITSATRINRAARRWEDLVEQVIRMRQEKLAHYE Fomme1 DSLPYYDNDLDVHPALKQKVEAELVRESRNERVESLDTIRYQLEDWQAALKNAKAQLEHQRIRQNNIALLQTYGTNAWKIQNYLMEHIAKELEKALEDLRNRTTDVNRERKQFQTKLGAQLTSLETRWTELISTVLQIELAEVNDLA Fusgr1 ESLPYVDQEPT--PEALAAARALITAE-ASERVSK-DLSRYEA-----ALPAAAVAHSYLSSRLTNLELLEKWGKNAWLLGNHGLEAELQALERELAVTKREVDIVNLERQKRQTAVGAEIKTLDDTWRAGVGRVLETEVAKIREEL Galma1 DSLPYYDDDLQKYPYLQEMVEQELGREPKAERVASLDTLRYTLEEWIAALDNAHAQLQHQRIRQQNLALLQTYGANAWRIQNHLLEATAKQTEKVLEELKELTVEVNRERKNTQDRLGKQLTALETRWTELISSVLQIEMAEVERLN Ganpr1 DSLPYIDKEYED-ECVRAEVDALIEEELQRDRVERIDTSRYRLEGWKKAVDNARAQLEHQYSRLINLELLNKFGPNAWKIHNFQLEATNASLQAKIDDYSRKIMELNKLRKLDQTREGQILRQLQAKWNEHVATHIQLETAEVKLLE Gloin1 DSLPYFDQEIDY-EGMRAKVDKLVEQEMKKQRVQLMDINRYKLEAWEKAVNNSKAQLQHQNLRMFNLELLQKYGANAWRLHNYQLENELQQYQKTLEEYKQNILDLNIQRKAEQLQTGNKIEALNNKWTEMIGQTLQVEVAEVQQLK Hisca1 DSLPYIDDEPT--AQARANIDKIISAEMDPDRKEAIDLSRYEADSWQQTLRRAYTSSTHLSTRQENLSLLDAHGKNAWLIGNSQLEEILRQIEKELQETKEATDAIHKERKMRQETAKGELVGLEDAWKRGVGGIIDVEVADILEKR Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 DSLPYYDDDLQKFPELKEKVDREMARELVQQRVEALDSLRYQLQEWKEALDNAHAQLQHQRIRQNNLALLQTYGPNAWRIQNYLLEETKKQTEKAAEELVQLTVEVNRDRKNTQDRFGKQLTQLETRWTELISSVLQIEMAEINRLN Lenti61 DSLPYYDNELEQYPILKQKVEKELAREGKPERVSNLDTTRYQLEEWRKALDNARAQLEHQKTRHLNLALLQQYGSNAWRIHNYLNEAAAQNIEQALEELKNLTTEVNRDRKNYQTRLGTQLTSLETRWTELISSILQIEMAEIDRLN Malgl1 DALPYYDTEIDHVRGLRETVEQAIEEEKQQERAKRIDTTRYQLEAWAHALRNAETQLAYMEARLNNIELLRRYGPNLWRLHNYQQEAMVAFEMRAKEHTSHEMDELNRTRKATHLHLGDKISTYESRWRDLVSRNLSIRVANMQEIM Mellp23 DSVPYLTTNPNK------------------LRSQSLDLERRKIEEWKTSLKNAKSQIEQQRI------------------------------------------------------------------------------------- Mnele DALPYTDEGYED-EKVRESAARLIEEEVKRERLDALSMKRCELSAWLSAVSNSRAQLEHQDVRLGNLELLKEYGCNSWTLYLQQLQRLSESQQAKLHALRQNIQDTNWARKREHTEAGNMLHKLEGEWLELVGKNYAVERAEVEKLE Monbr MALPYVDRDLEL-PGMQQAVDAALEAEMQAERKAKFATGRYNLNAWLEAVHNARAQLQHQCTRIENLELMTDFGGQKWMRYNEQLEQIKSDLENDLAAIKSRLDEMNWERQQEQTTAGQELYQLEVQWGQLVMQNYQLAVAQCKLQG Morel2 DALPYVDKQIDE-PGVRSMVDKLIASEMKRDRVRRLDLSRYQLAQWLKALDNANAQLEHQNQRVLNLELVQKFGGNAWNIHNYQLEYDVSLLRKAVDEKKAEIMELNKLRKRDQMDVAESLQRLEAKWAEMISSTLQVEVAELAQLK Mucci2 DALPYVDRELDD-AEMKTTVERLIEQEMRRERIKKLDTKRYELEGWKAAVNNTKSQLESQAGSMFNLELLQKYGANAWRVHNYQLENDLANIKKNTEHLRNQILEINRERKNDQTQAAASLKSLENKWSDLITQNLQVDIAEVEELR Mydma DALPYVDQGYDE-PGIREMVNELIEEETKRERISNLSMKRYELSAWVEALKNSMAQLEHQ---------------------------------------------------------GER--------------------------- Neucr2 ESLPYIDPEPT--PSERSAAEALIAAE-RSDRIASLDLARYSSTLLSSLLGKAYTDHAYVAQRRAHLALLDAYGKNAWLIGNWQLEGELKAIEKELAEAKREIDLVTLQRKQAQDEVGPEILGLEDTWKKGVGRVLETEAAQVLEVR Orpsp11 DALPYIDKEYDD-PEMKKYVDNLIEEELKVERIKNLDTIRYRLDEWKKAVENSEAQLEHQYNRLINLELLNKFGANTWRYNNFQLEQILNEIKGKVNDKKSKIIDINKERKYLQTKSEAKLQQLEQQWKENVSKVLEIEAAEIQAKK Pench1 DSLPYIDAAPT--ASAQARAQQLINAELSPARKAQIDLSRYEADTWRQTLQKAYASSSHLSKRHENLALLEEHGKNAWLIGNSQLEEILGSLEKELAETKEASEEVNKQRKIAQEASQGELVSLEETWKQRLGAILDVEVAQRLDYM Phybl2 DALPYVDREIDE-GDMKATVDRMIEQEMRRERVHKLDTSRYELEEWKSAVDNTKAQLESQAGSMFNLELLQKYGANAWRVHNFQLEAYLKQIQKATEEYRNESREINKQRKFEQTQAAGSLRSLENKWSDLISQNLQVDIAEVEELK Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 DSLPYYDNDLEQYPNLKQKVEQELAREPKPARVESIDTIRYQLDDWEKSIKNAHAQLEHQRIRHTNLALLQTYGPNAWRIHNYLLESTADQLDKALENLKQLTTEVNRERKNSQTRFGNQLNSLETRWTELISSVLQIEMAEVDRLN Polpo DSLPYIDAPIT--EGEQAIINEMIREEMTK---------------------NVRSH----------------------------------------------------------------------------YKSFD---------- Pucgr2 DSLPYYDRDLDVIPNLRQRIEREIELELKS---ADLDIERFNIKDWEDALSNAKSQLEHQRLRLINLDLIGKHGANHWKLSNFLVDQEISKLDKLVDHYKNEIDDVNRRRKAHQTDVGDRLTDLAQKWQNLVSTNISLEITEMEALQ Punst1 DALPYYDNELEQFPALRQKVEQELAREGKPRRVEALDTLRYQLEEWQAALKNAQAQLEHQKIRQTNLALLQQYGSNAWRIHNYLLEATAKKAEKDLEELKQMTTELNRERKNFQTRLGAELTSLETRWTELISTVLQIEMAELERLN Rhior3 DALPYVDRELDN-ENVKAEVERMIEQEMRRDRVQQLDTERYELEAWKAAVNNTKSQLESQAGSMFNLELLSKYGANAWRVHNYQLETYLEYIKNNTERVRNQILNINKERKMEQTQAAETLASLENKWSDLISQNLQVEIAEVNELK Rhoto1 DSLPYYDTPL---PELQPVINSLIAVELRNARVESLDTTRYAMEAWERAYRSSLAQLEHQRLRTMNGTLLQQFGANKWRVENFALENAIKRVEGEGEEVKGVVEDVNRRRKADQEKAGETLNRLEKRWTDLVSGTLQLEIGELVGLR Rozal11 DSLPYFDQEYEI-PEIKSEVDRLIEKELANERMDKLDMARYRLKEWIKAIENAYIQLEHQRIRATNLELLKAYGADAWNIYNQQMRELENYINRDLEFVKNNIIDINRQRKIEQIKAGNAIEGLELRTKEALDQLMQVQLAAKKQLS Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------- Salro MALPYVD-DIE---ASREQVNALLAEEMGSQEMEEFDTYRYDLEAWKESVKNAYAQLEHQRNRIDNLELMTQFGGQKWTRYVEQLQALQNRLQAALDAINQDMEDINWQRQNEQQAAGQEFYQLEVRWGELVAANYQLETIQQPQQE Schco3 DSLPYFDKDLETLPELRDKVDSEIAKEMGKTRIESLDTLRYQLEEWKKALDNAHAQLEHQRTRQTNVSLLQTYGANAWRIHNYLLETTAKNAEKALEELKEQITEVNRERKNTQTKLGEQITSLEHRYVELISSVLQIEMAEIERLT Schpo1 DSLPYFESTYN--EEDRSAAAQIVEEELKRDRLENIDVQRYIQ---RESLLQSAVVWEYQKSRNDNLYLLEKHGEKAFDSSLEALEVQLELLEKELVNTKKLSQGCNRKRKHYQMEVGARLAEAEVKFGQLLQSSIQCRVA------ Sorma ESLPYIDPEPT--PADRLAAEALITAE-RSERIASLDLTRYSSTLLQSLLEKAYTDHTYVASRRAHLALLDTYGKNAWLIGNWQLEGELKAIEKELADAKREIDLVTLQRKQAQDEAGPEILGLEDTWKKGVGRVLETEAAQVLEVR Sphar GPLPYVDSEYES-EDMRAMVDAMIEDEASKARVSTFDVKRYKVDAWRAATDHVATQLEMQHDRIINLELLIKYGKTAWLEHTKELELVKDTAQTQLEKITDDLEELNGTRAAEQQDAGMRLLDLQAQLTTFLDQKLEVQKAELQYLE Spipu1 DSLPYIDGEIS--PELSDEIASLLSHPRPT------DTTRLRLEAYKSAVENACAQLEHQNARMVNLELVHSFGSNAWKLHCFQLEYLKKKVDAQVEQIKKEVLEVNRERKMGQMKTGQTLQTLTYKYSQLLNQTIQVDAAEVEHLQ Sporo1 ------------------------------NRLQALDTSRYAMEAWERAHESSLAQLEHQRLRSINGTLLNQFGANNWRVQNFAMENAIKRTENEGESVKTTVEDVNRRRKADQEKGGETLNRLEKKWTELVSGNMQLEIG------ Stehi1 DSLPYFDKDRDENPVLAEQVAHVLAVETQQQRMERINADKNKLEEWKAALDNAHVQVEHQRIRHNNLALLQQYGSNAWRIHNYLLEADTKQEEKLLEQAREQATHVNRDRRAIQDRIGAQLDTLDTRWQGLVSSVVNIETVEVHRLN Tapde11 DALPYYDSEPS--ESDRDAVDSLVEKEIPQDRVKRIDLARYEQQDWRDALRRNIVAADAMNSRSDNLTLLKSLGTNAWTVHVHQLEYSLKQVESELLAVRQETEQVNIERSRAQTSAGDHLTELTERWRSLLSSNLELNVAEIDELN Thetr FSLPYVDTELEA---GAGVVDAELAAEYAAACMENLDLSRYSVEEVGPAVGNAAAVLEIAGARLMNAELGKEHAVGEWKAAVEQKEALIDAMTAALKRVEEEDEKVNRARAEAQLAKAGKIRGLESEYQQLVMKNAAIAEAEIKRTD Treme1 DALPYYDKQIDD-PHFKAKAQALIEAELRS----NIDVSKY--DELKEIEKRGWIGEGHMALRNENVQILSTYGPNAWLVRNYQLSTQLTELQAAVTEIKERVTELNRARRVFQEDTGQHLSRLEGRWQDLVGATVQLEMAEVEGLR Trire2 ESLPYIDPEPS--PEALSAARALIASE-QSSRIQS-DLSRYEAQATRRALQNAFVSSSYLSSRAQNLALLDAHGRNAWLLSNYHLEAELRSLERDLAAAKRDIDLVNAARAARQTDVKAEMQTLEHNWREGVGRVLETEIAQIRHEL Umbra1 DSLPYVDRELEI-AGMKDKVNLLIEQEMRKARTNKLDLSRYDVDAWESAIDNSKAQLEAQTLRLFNLELLQKYGANAWKVHNFQLEAYLKQLKSDVEDKKKQILDLNKQRKFEQTEGGSSLRDLESKWSDLISQTLQVEVAELEELK Ustma22 DALPYFDRELELQPGLRSRVDALIAEEQASERVASLDTHRYTLSDWQAAVDSAHAQLGHMDVRMKNIELLKKYGSNAWRLSNFQQEQNIRLLSEQLDLVKAETSEINRLRQKNHLEAGGKLATLNKRWTELISRGLQLEVAEVDMLK Walse1 DSLPYYDKELENDTKLRDAAAKLIADELANERAGKFDASRYALSEWKKSYNNAVIASEYQQLRSSNLDLLSALGANAWKLSNHTLDADARSLEQQSEQINNKIIDINRLRKSEQTKIGENLNTLEKSWGGLVSNNLELEVAELAQLA Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2646.fasta_al_trimmed; alignment length = 198] Allma1 SQHSHSGQFC-RHGGKLEQVVQEAIRQGFISYALTEHVPRFALYPEEAFLVEARRLQRVYQIDLVVGCETE-YIPLLVVGSVHHVGGTPIDFSYFDAQLDLITRVRPHVIGHFDLIGIFMW-PRVERNIRAAVAAGSLFEINARAWKK-GGYPHIEVA--KTIASLGGRFTLSDDAHGVGLNYRQHVPTYLAEGVEEL Ashgo11 SHHSHSGEYV-AHGDTLEAVVAEALRQGFHTYCLTEHMPRLDLYPEERYVEHAARLR-QHGMAVLVGMEAE-ACVQFCVGSVHHVYGIPIDFSYFDWQYYMLRELQPEVVGHFDLIRLYVQ-SRVVRNLEYIASYGGLVEINSAGLRK-GPYPHRDVA--LLVKRYAGRFVLSDDAHSVGTEYV-RTLEYVENQLEGL Aspfu1 SHHSHSGQFCPGHADSLEEIIKLAISKKFKVFCLTEHMPRAKFYPEEAYFAEAVRLREKYQIQILIGFEID-WIFEFFVGSVHHTLTVPIDYDYFDEQLDMVTQLRPLVVGHFDLIKLKVW-ERILRNLDFIAGYGGMLELNSAALRK-GPYPKEEIC--REFLARGGRFVLSDDSHGVGFNFH-GVLAFM-EGISTL Aurde31 SHHSHSGQFC-RHAGQLEDVVKTAIERGFTVYGLSEHMPRYRLYPEEQFISEARRLKQVYRISLLVGLETE-HIVDYMVGSVHHAGEIPIDFDYFDAQYELLQRVRPTIIGHFDLCRLYVW-TRVRRNVEFAVSYGALFEANAAAFRK-GAYPGPDVATKQLILELGGRFVLSDDSHGVGLNYP-RLREYLLSGVREL Batde5 SLHSHSGQYC-MHAGQLEDVVKRAIELGFQVYGLTEHMPRTRLYPEEDFYIHAQALQAKYQITLLIGMETE-LIFDYLVGSVHHVRGFPIDFDYFDAQYSLIDQIRPAVVAHFDLVRLFVW-TKIDRNIQLISQYGGLVEINSRAWKK-QAYPQRDIL--KKMIDAGLRFCVSDDSHGVGMHYD-RLAVYLAEGIHEI Botbo1 SHHSHSGQFC-KHAGLLEDVVQTAISKRFHVYGLTEHVPRYRLYPEEAFIAEASRLRTTYRISLLVGLETE-YIIDYIVGSVHHVHGFSFDFDYFDAQHDIITRFQPEIIGHLDLCRLFVW-AKVDRNVRAAIAYGALFEFNAAAFRKPGAYPGRDVV--QLILGHGGKFALSDDSHGVGLHYD-KLYAYLRDGISEI Botci1 SMHSHSGQFCPGHADTLEQVIQMAISRGMQTFALTEHMPRNSLYPEEAYLVEATRLREKYELNILIGFEGE-WIIDFFIGSIHHVNEIPIDYDYFEQQYELLQTLKPKVVGHFDLIRLLVW-DMVLRNLLEVVKYGGLLEINTSALRK-GPYPGRQIC--EAYIRFGGKFTMSDDSHGVGPNFV-KAIDYI-EGVEEL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 THHSHSGDYV-SHADTLNDMVELYYKKGFQIICLTEHMPRLDLYPEERYLNHARDLQLKYNMKIIIGFEVE-GIVQMSVGSVHFVNEIPIDFNYFELQYKVITQLKPTVVGHFDLIRLLIW-QLVIRNIKFVKSYGGLFELNSSALRK-GPYPKRDIA--NAIIEYGDRFCLSDDAHSVGIFYS-KAWEYV-EGMENI Cangl SHHSHSGDYV-AHGDPLDDIVAQAVAMRFHTYCLTEHMPRVNLYPEESYLEHSRSIRAKYKTKFLVGCELE-CCLKFTVGSIHHIRGIPIDFDYFDMQHAMITELQPIIIGHFDLYKLLLR-EKIIRNLKAIDSYGGAIEINTAGFRK-GPYPGPEIC--ELAKQYCGRFVLSDDAHAVGTCYK-QALDYITNKIEAL Capow TYHSHSGQFC-LHAGTLEAVVLRAIDAGFTHIGLSEHMPRTRLYNEEAYIAEARRLRDKYRIHIVIGMETE-YFIEYLVGSVHHVHGIPTDYSYFEHQYALINALQPQVVGHFDVIRLYTW-ELIDRNIRCAVSYGALFEINSRALKK-MPYPQLDIA--QRILSLGGKFTICDDSHGVAMHYD-QLPSYLELNIDTV Catan2 SQHSHSGQFC-RHGGILEDVVLAAIDRGMVAYALTEHVPRYSRYPEEAFLAEARRLQVKYQIDLIVGCETE-FVPFLLT-----VGSSPL---YFDAQFAMLELVQPKVVGHFDLIGIFLWDSHVKRNLDWIAAHGALVEINSRAWKK-GGYPHVAIA--KRIKNEYGRFTLSDDAHAVGMGYVEQVRRYIEQGLAEL Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 SHHSHSGQFC-SHADTLEQVIQAAIAKGFHTFALTEHIPRPIFYPGEDFIVEANRLRDKYQIQILIGFESE-WIFDFFMGSVHHVHTIPIDYDYFDSQWEMLQALRPPVVGHLDLIRLLVW-QKIERNLAFIASYGGLLELNSAGLRK-GPYPCLPIC--QMFLRMRGGFVMSDDSHGIGTNYA-RLLAFI-QGTDRI Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conco1 SFHTHSGEFC-NHAGRLEEVILRAIELKFDTIGLTEHVPRFELYPEEAYYKKANELKLKYKINILIGAELE-YIFDYLMGSLHHVNNIPIDFDYFEDQFNLIKKFHPKVIGHFDLIRLFIK-EKIDRNIRYIVEYGGLFEINTRSLKK-SPYPQPDIL--KMILELGGKVTLSDDSHGVGMHYD-KVLDYLSLGIDKV Conpu1 SHHSHSGQFC-KHAGTLEEVVLAAIERGFEVYGLTEHVPRYRLYPEEAFVEEAHRLKRAYKISLLVGLETE-HIIEYIVGSVHHVNAIPIDFDYFDAQYKVLERFLPAIVGHVDLCRLYGW-NGLERNVKFAVNHGLLFEANAAAFRK-GGYPSWEVL----IKQYGGRFALSDDSHKVGLNYA-RLHDYLQAGVTEL Copci SHHSHSGQFC-KHAGKLEEVVQEAIRQKFQVFGLTEHVPRYRLYPEEAFLAEAHRLKDLYQITLLVGLETE-HIVEYIVGSVHHVDGVPIDFDYFDAQYQLLERFKPEVVGHFDLCRLFVW-EKIIRNIKFSVSYGALFELNAAAFRK-KAYPGEDII--RVILGHGGRLALSDDSHGVGLNYH-RAYDYLKSGVSEL Croqu1 SLHSHSGQFC-KHAGQLDHVILTAIEKQFKSYGLSEHMPRNRLYPEEQFIIEATRLKAKYKISLLIGIETE-VIIDYLVGSVHHVNQIPIDFDYFDAQYRLMTRFQPEVIGHFDLCLLYVW-DKVKRNVSFGISYGALFEVNSAALKK-GPYPGPAIL--HLICEMGGRLTLSDDSHGVGLNYS-GVLEYLSKRIRSL CryneH991 SHHSHSGQFC-RHADKLEDVILEAIRQGFQSFGLSEHAPRWRLFPEEDFLKTALILRSKYRISLLVSLETD-YIIDYIVGSVHHVNGVSIDFDYFDAQYDLIVTHQPEVLGHIDLCSLWVW-QKVIRNVKAVIAYGGLFEANAAAIRK-GSYPCRDIL--QLIQELGGRICLSDDSHGVGLNYL-KMRDYLKNGLERT Crypa2 TMHSHSGQFCPGHADQLEDVIKHAISIGYKTMGLTEHMPRTGLYPEEDYLLEAQRLQAKYQLHILIGFEGE-FIVDYFIGSLHHTCGVPIDFDYYDEQHAMLTALRPRVVGHFDLIRLLVW-DRIVRNLEAVRAWGGWLECNSSALRK-GPYPARPIA--EEWLRMGGRFTLSDDSHGVATNYR-RALDYL-EGVKEV Debha1 SHHSHSGTYV-SHADDLESIVRKAQSMGFTHFCLTEHMPRLELYPEERYLEHAKKLQDKYRMKILIGFEVE-GIVNMSVGSVHYVNQIPIDFSYFDLQYNVVLTLKPPVVGHFDLIRLFVW-ESITRNVKFINDYGGLFELNSAAIRK-GPYPKKDMC--GAILKYGNKFCLSDDSHSVGLNFH-KAWEYARDNLDYI Dekbr2 SHHSHSGEYI-AHGNTLDEVITKVKQMNFHVFCLTEHCPRYAMYPEEKYMVHARRIQKEIRLRILVGFESEGGIVDIVVGSIHYVKRIPIDFDYFQCQHEMIKRLKPEVISHFDLIRLLVW-KLIDKNIDLINEQGGLIELNSAALRK-GPYPKRDIV--ELALSKG-KFCMSDDSHGVGLNYD-KVLKFI-QKMPYI Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 SHHSHSGQFC-RHAGTLEEVVLEAIRQKFQIYGLSEHVPRYRRYPEETFVKEAHRLKDLYEITILVGAETE-YIIEYLVGSVHHVNEFPIDFDYIDAQYDLFTQFHPEIIGHFDLCRLYVL-AKIERNISYACDYGALFEFNAAAFRK-GAYPGKDIV--EKILQKGGRFTLSDDSHGVGQNYN-KLYIYLEEGIKEL Fusgr1 TMHSHSGEFCPGHADQLEEIVKQAVSIGYKTIGFTEHMPRYDLYPEESYLVEAQRLRHKYQIHILIGFEAE-FIVDYFIGSVHYVHNMPIDYSYYDLQYEMLTELKPRVVGHFDLIRLMAW-DRVLRNLTLAKEQDGWLEVNSAALRK-GPYPGRQIA--EEWIKMGGKFTFSDDSHGVATNYA-RTITYL-EGVKEV Galma1 SHHSHSGQFC-KHAGLLEDVVQEAIRQHFQIFGLTEHVPRYRLYPEEDFLEEAHRLKSCYEITLLVGLETE-YIVEYIVGSIHHVNGIPIDFDYFDAQYELLRHFKPEIIGHFDLCRLYAL-EKIERNIRYAVEYGALFEINAAAFRK-NAYPAGDIV--EIIHSHGGRFALSDDSHGVGLNYE-RLPQYLQSGISQL Ganpr1 SFHSHSGQFC-RHAGTLEEVVQSAIAKGFSVLGLSEHMPRTRMYPEETYVVEARRLQKAYKIHLLVGMETE-HVLEYLVGSLHHVDGIAIDFDYFDQQYEMFLALKPEVVGHFDLVRMWVW-TRVKRNVNFVVQYGGLFEVNSRAYRK-GAYPMREIL--EYMLSRHARLTISDDSHGVGAHYE-RACAYLRSGVNSV Gloin1 SHHSHSGQFC-QHAGMLEEIIQEAIKKKFIVYGLSEHCPRYRLYPEEEFVKEARRLQEKYQITLLVGLESE-TILDYVVGSVHHVHETPIDFDYFDSQYQMLQNIKPIIVGHFDVIRIYIW-KKVERNIDYVVNYGGLFEINSAGFKV-GAYPQRDIL--QLILKKGGKCTISDDSHGVAMHYD-RLYNYLKENINVL Hisca1 SHHSHSGQFCEGHANSLEDIIRTAIGKKMCVFALSEHMPRMAFYPEEAYFKESQRLREKYEINIPIGFECD-WIFDFFVGSVHHVHTIPIDYDYFDAQFAMLKALNPPVVGHFDLIRLKVW-EKILRNLDYVAEYGGILELNSASLRK-GPYPKAEIC--KEFLARNGRFCMSDDSHGVALNYN-RMLEFT-EGISTL Klula1 SHHSHSGDYV-AHGDPLEDIITEVKRRKFHTWCMTEHMPRLELYPEEAYMIHAKRIK---GLHILIGFEIE-GCLQFMVGSVHHVHNIPIDFNYFTIQRKMLETTQPLVVGHFDLIRLFVK-QLIVESLKYVVSYGGVVEINSAGLRK-GPYPHRDIV--NLSKEVTPRYVTSDDAHGIAVCYD-EMLNYIENQLKQI Lacbi2 SHHSHSGQFC-KHAGSLEEVVLEAIRQQFQLYGLTEHVPRYRLYPEEKFLVEAHRLKTHYQITILVGLETE-YIVEYVVGSVHHVDGIPIDFDYFDAQYQLLQRFKPEIVGHFDLCRLYVW-EKITRNVEYAIGYGALFETNAAAFRK-GAYPGKDIV--QLILNCGGRFALSDDSHGVGLNYH-RLLDYLHAGVTDI Lenti61 SHHSHSGQFC-KHAGTLEEVVLEAIRQGFRTYGLTEHVPRHRLYPEEAFLTEAHRLKEKYQITLLVGLETE-YIIEYIVGSVHHVAGIPIDFDYFDAQYTLMQRVQPEVIGHLDLCRLYAL-ARIRRNVRYAVEYGALFELNAAAFRK-GAYPAEDVV--EIIRENAGRFTLSDDSHGVGLNYS-RLVEYARRGIDEL Malgl1 SHHSHSGEFC-RHASTLDQVLARAYELGFTHFHLSEHVPRWRLYPEEAYLVKARTLQRMYPMHVLVGCETE-HIVDYIVGSVHHIRGVPIDFDYLDAQFEVMDRLRPEVIGHFDLYRLFIH-AKLKRNIHFAASYGALFEVNSAAFRK-GTYPGRHVL--RMITKACGRLALSDDSHGVGLNFA-RLREYLLNGISKV Mellp23 SLHSHSGQFC-KHAGNLEDVIKTAIQKGFISYGLSEHMPRNRLYPEERFIIEANHLKSKYQINLLIGIETE-MIIDYLVGSLHHVNQIPIDFDYFDAQYALMVRFQPEVIGHFDLCLLYIW-DKVERNIKFGMSYGALFEVNSAALKK-GPYPSPDIL--KLISKFGGRLTLSDDSHGVGMNYA-RVLDYLTQQVKEI Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr SVHSHSGQFC-SHADSLAEIVHTAHERGFSHYGLSEHMPRANLYPEESYVQEARRLQQAYRLSIAVGMETE-FCLDYIVGSVHHVDGIAIDFDYFEHVRTMIEALQPTVVGHFDLFRLFVL-DAALRALTAGLEHDCIFEINTSGLRK-GPYPHADLL--KMMLERGARLTISDDAHGVGTNYG-RLRQYLLDGVTEL Morel2 SLHSHSGQFC-MHAGTLEQVVQSAIDRRFTTYGLSEHMPRYNLYPEEQFLLEAVRLQSKYQICLLIGLETE-YFVQYIVGSLHHVHGVPLDFSYFDAQYEMLQGLEPEVVGHLDLVRIFLW-TLVKRNVDFVIGYGGLFELNSRAWKK-GAYPQRDIL--EYILSKNGRVTLSDDSHGVGMFYNPELKQYLNQKVQQV Mucci2 SFHSHSGQFC-KHGGLLEDVVKEAIRKGFHAYGLSEHMPRYALYPEEDFQVEAKRVQQLYQISIVIGAEIE-FIADYVVGSLHHVDSTPIDFSYFDEQHVMLQCVQPEVVGHFDLIRIFVW-KRVIRNIDLVVKYGGLFEINSRAW---------------------------------------------------- Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 TMHSHSGQFCPGHADQLEEVIRHAISVGYRTIGLTEHMPRTQLYPEESYLAEAQRLQAKYQIHILIGFEGE-WIVDYFIGSIHHTAGIPIDFDYYDEQFEMLNATRPKVVGHFDLIRLLVW-ERMKRNLEVCKGLGAWLEVNTSALRK-GPYPGREVA--EEWIKMGGKFTFSDDSHGVATNYT-RGLDYL-EGVTEL Orpsp11 TLHSHSGEFC-CHAGNLEDVVLTAIDKGFICIGLSEHIFRTRLYPEEKFVKEARRLQKKYKINILVGTETE-NILDYMVGSVHHVFETPTDFDYFDSQYEIITQLKPKVIGHFDVIRMYTW-SKIKRNVNAVNSYGGIFEINSRAWKK-GAYPFKDIL--QYIISQNSKITLGDDSHDVGLYYD-KLYDYLKENIKKI Pench1 SHHSHSGQFCPGHANSLEDVIRTAISKKMQVFCLTEHMPRHKFYPEEAYWKEAVFLREKYQIRIIIGFEID-WIFEFFVGSVHHMHTVPIDYDYFDAQLDMLKQLKPLVVGHFDLIRLKVW-SKILRNLDFIASYGGMLELNSAALRK-GPYPKAEIC--KEFVARKGRFCLSDDSHGVALNFR-PMLDFL-DGISML Phybl2 SYHSHSGQFC-HHGGKLEDVVKQAIRKGFKVYGLSEHMPRFDLYPEEAFLVEARRLQEVYQIELLIGAEIE-FIIDYVVGSLHHTHSIPIDFSYFDEQYKMLLSVKPEVVGHFDLIRIFVW-EAVVRNVDFVVSYGGVFEINSRAWKK-GAYPQREII--KLIQSKGGKFTLSDDCHGVGMFYD-KLHQYLKDGIKNI Picst3 SHHSHSGDYV-AHADSLDSIVQLAHSRGFTIFCLTEHMPRLDIYPEERYLAHAAKLQLHYTLKILVGYEVE-GIVNMTVGSVHHVHEIPIDFDYFSLQGKVIARLQPTVVGHFDLIRLFVW-NLIVENIKRVKSYGGLFELNSSAIRK-GPYPKKDIA--EAIIQYGGRFCLSDDSHGVGLNYH-KVWQYITDKLDTI Plicr1 SHHSHSGQFC-KHAGTLEEVVLEAIRRGFETYGLTEHVPRYRMYPEESFLTEAHRLKASYRIALLVGLETE-YIIEYIVGSVHHVNRIPIDFDYFDAQYEILHRLHPEVIGHIDLCRLYAW-KKLERNVDYAISYGALFEVNAAAFRK-GAYPGADVM--QLIQRRQGRFALSDDSHGVALNYK-RLADYLRRGVTEL Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 SLHSHSGQFC-KHAGTLDSVIRTAIDRGFISYGLSEHMPRDRLYPEECFIAEAGRLKQLYQIGLLVGIETE-LILDYLVGSVHHVNQIPIDFDYFDAQHTLIERYRPEVIGHFDLCLLFVW-TKIERNVRLAISYGALFEVNSASIRK-GPYPSPPIL--QLIISLGGRLTLSDDSHGVGLNYD-KSFDYLKMNVSTL Punst1 SHHSHSGQFC-AHAGNLEDVVREAIAQGFVVYGLTEHVPRYRLYPEESFLHEAWRLKAQYQITLLVGLETE-SIIDYIVGSVHHVNEIPIDFDYFKSQHTLLERFKPAVVGHFDLCRLYAY-AQMEANIALAIGYGALFEVNAAAFRK-GAYPGTDVV--EVILRHGGRFCLSDDSHGVGLNYH-RIPAYLARGVTEL Rhior3 SFHSHSGQFC-KHGGLLEDVVKEAIRKGFHVYGLSEHMPRYALYPEEDFRLEAERLKEAYSISLLVGTEIE-FIADYVVGSLHHVNSVPIDFSYFDEQWEMLQAIQPEVVGHFDLIRIFVW-QRIVRNVDYIIGYGGLFEINSRSWKK-GAYPQRNII--QIIKEKGGKFTLSDDCHGVGLFYE-KLPNYLLEGIDTI Rhoto1 SHHSHSGEFS-CHAGTLAEVVDEAIRQGFTTFGLSEHVPRYELYPEEKYLVEAHRLKKLKELSILVGLETE-YIIEYLVGSVHHCDEQPIDFDYFDNQLELMKRLEPEVIGHFDLCRLYVW-SRIERNVDFAVGYGALFEVNASAFRK-GAYPGVEVF--DLILRKGGRFTLSDDSHGVGLHYD-RAYAYLRENVREL Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 SHHSHSGDYS-AHGDPLDSVVDQVVNLNFHTYCLTEHIPRIEIYPEENFMSHAQEIKTRYRTKFIIGMEIE-SCLKFCVGSVHHVNGIPIDFDYFQSQYEMLINIKPLVVGHFDLYKLFIY-DAVVRNLQFIDSYGGAIEINTSALRK-RPYPSKTLC--NLVKKHCGRFVLSDDAHGVGVCYD-KVKKYIVDQLEYI Salro SYHSHSGQFC-KHAETLEANVLAAIELGFTHLGLSEHMPRYCLYPEEAYVQEARRVKAKYKIHLVIGFETE-MCLSYCVGSVHHVNGVPIDFDYFELVKEMIEGIKPAVVGHFDLIRLLIL-AAADAAINAAVKHNCLFEINTAALRK-GPYPHADLA--LRIAQRGARFTISGDSHCVATCYA-ALPAYLDAGVDAI Schco3 SHHSHSGQFC-KHAGTLEEVVQEAIRQKFQLFCLTEHVPRYRLYPEEAFLEEAHRLKKLYQITILVGLETE-YIIELLVGSVHHVNSIPIDFDYLDSQYEVMQRLKPEVIGHFDLCRLYVW-GRVQRNIQFAIGYGALFEINAAAFRK-GAYPGKEVL--QYILANKGRITLSDDSHGVGLNYT-RMKKYLQGGVKDV Schpo1 SSHSHSGQFC-LHAGKLEDVIQEAIQQGFQSFSFTEHTPRDRLYPEEEYVNEARRLKQNYQINILIGAETE-YILDYFVGSVHHVNSIPIDFSYFEHQYDLMQRLHPLVIGHFDLICLFVW-ELIQRNIKYAVSYGGIFEINTSAFRK-GAYPQQRLL--ELMVEQGAQLTLSDDSHGVGLNYH-LAKSYLDKGITSL Sorma TMHSHSGQFCPGHADQLEEVIKHAISVGYKTIGLTEHMPRTQLYPEESYLAEAQRLQAKYQIHILIGFEGE-WIVDYFIGSIHHTAGIPIDFDYYDEQHEMLNATRPKVVGHFDLVRLFVW-RRMKRNLEECKGLGAWLEVNTSALRK-GPYPAREVA--EEWIKMGGKFTFSDDSHGVATNYA-RGLDYL-EGVTEL Sphar SL-SHASLSC-IARSYLEGLIMAPLMQGFTCLGLSEHMPRCKMYPEEQYVRTARSMQRSARITLLVGLESE-YTLDFIVGSVHHVEGIPIDFDYFDHQYEVIQHLKPEVLGHFDVVRLLVW-AAIRRNVKLAIETGCLFEVNASGLRK-GAYPLPDIM--HYIVQQGAKFTISDDSHSVATHYA-QLKEYLIKQVTQL Spipu1 SLHSHSGQYC-LHAGELEDVVLRAIELGFEVYGLSEHVPRSRLYPEEAFVANARLLQEKYQIRLVIGAETE-HILDYVVGSVHHVKGHPIDFDYFDAQYEMLLRVKPSVVGHFDLVRLFVW-TKIHRNIDAITGYGGLVEINSRAWKK-GAYPQRDIL--ECMKEKGVRFTLSDDSHGVGMHYD-KLRDYLVEKITTL Sporo1 SHHSHSGEFC-LHAGTLVEVVEEAIRQGFTTFGLSEHIPRYKLYPEERYLSEANRLRELYKITLLIGLETE-YIIDYIVGSVHHCDELPIDFDYFDNQYKVIDRLRPEVIGHFDLCRLYVW-NKIERNIDLAVSYGALFELNASAFRK-GGYPGVEVF--DAILERGGRFTLSDDSHGVGLHYD-RAYLYL------- Stehi1 SLHSHSGQFC-KHAGSLEEVVNVAVKHGFEIYGLTEHVPRYRLYPEEDFLDEAHRLQTCFQIALLVGLETE-HIIDYLVGSVHHVNGLPIDFDYFDAQYELIRRFYPEVVGHIDLCRLFAW-AKLERNVAFAVAYGALFEVNAAAFRK-GAYPGIDTL--QLIQRLGGRLTISDDSHGVGLNYS-RMHTYLQQGVSEL Tapde11 SHHSHSGQYC-THAGDLEDCIREAIKQKFEIFCLTEHIPRYRLYPGEKYHAHARSLQKKYQLEIFVGLETE-YIIDMMVGSVHHVNEIPIDFDYFDHQYEVLKLFKPLVVGHFDVVLLFVA-SKIKRNIDLIISYGGMIELNSAAFRK-GAYPKPDII--RLIQESGGTFCISDDSHGVGLNFH-RLQEYIKDGISDL Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 SHHSHSGQFC-RHADTLEEIILEAIRQRFETYGLTEHCPRYRLYPEESFLSTARSLQSSH-ISLLIGIETE-YIIQYVVGSIHHVKGIPIDFDYFDSQYQLLVNLQPEVIGHFDLCLLYVW-EKVKRNVVYVVGYGGLFEANSAALRK-GSYPSKDVL--ELIIQLNGRICLSDDSHGVGLNYH-RMRSYLLSGVDQI Trire2 TMHSHSGQFCPGHADQLEDIVLHAISLGYKTMGLTEHMPRYELYPEESYLLEARRLQNKYQIHILIAFEAE-FIIDYFIGSVHHVHGIPIDYDYYDLQFDMLKALKPRIVGHFDLIRLMVW-DRICRNLEYAMEIGAWLECNTAALRK-GPYPGRVIS--EKWLQLGGKFTMSDDSHGVATNYS-RGLAFL-EGVEHV Umbra1 THHSHSGQFC-HHAGQLEEVILSAIKKGFHTLGLTEHMPRFSLYPEEDYLVEARRLQQAYQINILVGCEIE-FIIDYVVGSLHHVHGIPIDFSYFDEQYQMLQAVHPEVVGHFDLIRIFVW-DKITRNVELVISYGGLFEINSRAWKK-GAYPQRDVF--KLIQDRGGKFTLSDDSHGVGLYYN-KLQAYLREGVGSL Ustma22 SHHSHSGQFC-SHADTLAQVLSRAQSLGFTHFHVSEHVPRQNLYPEESYLKEARRLQKEYSLHVLVGCETE-NIVDYIVGSLHHTNTIPIDFDYLDDQLEVLQRLRPEVIGHFDLFRLFIW-AKVERNVSFAVEYGALFECNAAAFRK-GSYPAKEVL--DLIIGMGGRVCLSDDSHGVGLNYM-KLRRYLMDGVQTI Walse1 SHHSHSGQFC-RHAGDLEDVIKSAIDKNFRLFGLSEHAPRYRLYPEEDYLSHAHKLRENYSIDLLVGLETD-YVIEYIVGSVHHAFETPIDFDYYSRLLHLVKTLEPEVVGHIDLIRLYAW-KLIEDIVKHVASYGGLIEVNAAAIRK-GPYPASDIL--SIIRNNGARLTLSDDTHTVGLNYW-RVFEYLKSDVTDI Zygro1 SHHSHSGDYV-AHGDPLEDVTSKAIEKKFHTYCLTEHMPRINLYPEENFLRHAKAIQ---NTKFIVGTEIE-GCVKFCVGSVHHIRDIPIDFDYFNLQYKMLTVLKPLVVGHFDIYKLYVH-KAVVRNLQFIESYGGLIEINTSALRK-KPYPGRDIC--ELVKTYCGRFVLSDDAHAVGVCYE-QALKYITEQLTQM [Cluster2647.fasta_al_trimmed; alignment length = 125] Allma1 D-TGNKVSRKSV-ICGSQNIVLGGKTIIQRGDLRRVAIGKYCVLSARCVLRPPYKTFYYPMKLGDYVY-VGEDTIV-EAATIGNFVQIGNNCVIGRFAIIEDGTVVPPHAVISSFSIVRAGELPE Ashgo11 S-NGNRISKKAT-ITGSQRILIAGSCLIREGNVRTLSMGRFCMLGRASVVKPAVIGYHCPLVMNSYTL-VKPGAQI-HCKRMGSRVVVGANSILARCCTIEDDVVVPENCYVPSFSRVRITPLND Aspfu1 D-TGNKISRRSQ-IHGTQHIILGGKTVIQRGDLYR-TIGRYSYISRQAVLRPPSRLHFYPLKIGDHVF-VGERAVV-EAAMVGNHVHIGREAVVGSMAIVLDGAVVPAGMVVPSWCVVGVGEVGE Aurde31 D-TGNKVSRRAV-ISGPQNIILGGKTIISRGDLRRTSLGRYCVVGEGCVIRPPYKTYYYPMKIENHVH-IGAGSIV-EAATIGNHVHIGKNCIIGKFAIIADNTVLPANTVVPALSLFAVEDLPE Batde5 D-TGNKVSRKAH-IYGIQNIVLGGKTIIQRGDLRRATTGRLCQIHSNVIIRPPYKLYYYPMKMGDHVI-IEHGSIV-EASSIGSYIHIGKDCVIGRFVVILDGAVVPANTVIPPFSVFGHFDV-- Botbo1 D-TGNKVSRRAT-IAGPQNIILGGKTIIARGDLRRTSLGRYCLISDGCILRPPYKTYYYPMKIGDHVH-IGSNSVV-EAATIGNHVQIGKNCIIGKFTIIADNTVIPPNTVVPALALFAVEDLPE Botci1 D-TGNKVSRRSQ-IIGTTNIILGGKTVIQRGDLLRTAIGRYCFFSRGCELRPPGKIYYFPLKIGDHVY-VGPGSII-EAAMLGNHVNIGANVVVGKFVIILEGTVVPPNMVIPSFSVVGVGEVAE Caeel H-TGNKVNKKHA-IAGTQNILIAGKTIIERGDLATVKIGKYCVLKSRCNIRPCMKIFMCNVMIGDYVF-IEEECVV-NAAQIYAFVHLGARAVLGNGCVVLPDTVVPADALFPPYSTIGVGTEPR Canalb1 P-PENRISKDAQ-IESLDNIVISGYVTINSLDPPTPSIGKYCYIYPDVEITPSTEKM----FIGSYVI-IGSSSKI-MAKDIGNRVIIEDNCVVHPHCVIKSGTIIPNKVVIPPYSKVSIQPLHN Cangl ----------------------------------------------------------------------------------------------------------------------------- Capow N-TKNKISRHST-VCGTQNIVLGGKSIVHRGDLKHIQVGKYCILSKRSVIRPPHRLYFFKLEMEDYVV-IGEDSVV-AAAKIGSYVQIGKNCVIGARCIILDNTVLPPDTVVPPFAVFGVDQLPE Catan2 D-TGNKVSRKSV-ICGSQNIVLGGKSIIQRGDLRRAAIGRFCILSARCVLRPPYKTFYYPMKIGDHVY-IGEDSIV-EAASIGSCVQIGRNCVIGRFTIIEDGAVIPPHSVIASFSVISVGELPE Cioin A-TGNKVSRQSV-LCGSQNIVLNGKTIVQRGDLANVRVGRHCIIKSRSVIRPPFKKFFFPCVIGDHVY-IEEDSIV-NAAQIGSYVHIGKNCVIGRRCVIADNTILPPETLVPPFKLYGVEDLPE CocheC53 D-SGNKVSRRSA-ITGTANITLGGRTVIMRGDLHPTSIGRCTVISQGSVIKPPSRISYYPMKIGDNVFVVGPNSTI-QAISISSHVHIGNHCTIGPFVIILPHTVVPANMVIASGSVIGVGDVGE Coere1 D-TGNKVSRLSL-ISGSQNIVLGGKTIVHRGDLRRALIGRFCSLGEASVLRPPYKTYYYPLKIGDHVD-IGENSVV-EAASIGSHVRIGKNCIIGRFAIIEDNAVVAPNAVIPSFSVVAVAQLPE Conco1 ----------------------------------------------------------------------------------------------------------------------------- Conpu1 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTAMGRYCVVGEGCIIRPPYKTYYYPMKIGDHVH-IGQNSVV-EAATIGNHVTIGKNCVIGKFTIIADGTVVPPNTVIPALALFAVEDLPE Copci D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTSLGRYCLVGEGCIMRPPYKTYYYPMKIGDHVH-IGANSVV-EAATIGNHVEIGKNCVIGKFTIIADNTIIPPNTVIPALSLFSVEDLPE Croqu1 D-TGNKVSRKAL-ISGSQNIILGGKTIIQRGDLRRAGIGKFCLLGERSVIRPPYKTYYYPMKIGDHVH-IGVDSVV-EAASIGNLVNIGKNCVIGRFSIIADNTVIAPGSVIASMSYYAQSDLPE CryneH991 D-TGNKVSRKAL-IAGATNIVLGGKSIIQRGDLRRSSVGRYCLIGEGAVIRPPGKMYFYPVRIADFTH-IGPNCII-EAAQIGSCVEIGEGSIIAAWLTLGVKAII--NGFVPPINV--LSWLSL Crypa2 D-TGNKVARKAT-LVGTQNIMLGGKTVIMRGDLARTAIGRYCFLSKGCCLRPPGRMYYMPLRMGDHVF-VGEGTVV-QAATIGSHVYIGNNTVIDEFAIILDGTVVPPNMVIPSFTIVAVGEIPE Debha1 T-SGNRISKKSK-IFGSNSILINGNCTINQGDVRIAQIGKCCYLGTGAKITPPVLKYHGPLLIGGYTI-IGKNSVV-RLANIGSRVLVELGCDLGNLSIIRSGTIIPPKMVIPPFSDVSIKDLSN Dekbr2 A-SHNRIHKSCM-VQGSSFIAIQGDTIIDDEDAKTTKVGKQCFFKEGCSVN------SPEMVIGSWCI-IGNNSVLRDCAAIGSRVIIGKDCRIDADCTIEDGAHLPSQFVVPSLTKVS------ Dicdi L-NGNKVSKSSI-LCGIMNIRLHGKTIIKRGDLASVNIGRLSIISENTVIRPSSKKFYFPQNIGDHVL-VGEGCVI-SAASIGSNVYIGNNCIISKRCIIADNTILPPDTVVPPFTYYSKEDLPD Dmel A-SGNKVSRHTV-LCGSQNIILNGKVIVQRGDLANVRTGRYCVIGKNSVIRPPYKQFFFPMHVGEHVF-VGEGAVV-SAATIGSYVYIGKNAIIGRRCVIEDGAVLPPETTVSSYMRYT---VPA Enthi ----------------------------------------------------------------------------------------------------------------------------- Falba R-DGARVSRQAS-FYGSQNLILAGQAVIERSDLRRISFGVGVIVESGAVVRPPGKITYYPQEIGPHVL-IGAGAVV-EASLIDSRARIGAGAVVGRFATVCPGAVVPPYSSVPPGAVVAAHQRPG Fomme1 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTQLGRYCVIGENCVVRPPYKTYYYPMKIGDHVH-IGAGSIV-EAASIGSHVEIGKNCIISKFVIIADNTVLMPGCVVPALAHFSVEDLPE Fusgr1 D-TGNKVARKAV-LVGTQNIMLGGKTVIQRGDLARTAIGRYCFLARGVLLRPPGRMYYMPLRIGDHVF-VGQGTVV-QAAAVGNHVQIGRDCTIGEFAIVLDGSVVPPNMVIPSFSIVAIGEIPE Galma1 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTSLGRYCLVGEGCVMRPPYKTYYYPMKIGDFVH-IGANSVV-EAAQIGNHVEIGKNCVIGKFTIIADNTIIPPNAVVPALSLFAIEDLPE Ganpr1 D-TRNKISRKSI-ISGPANIVLGGKTIVQRGDLRRTALGRYCVLERGCVIRPPFKTYYYPVKIGDFVH-IGSNSVV-EAASIGNGVRIGKNVVVGRFAIILDGTVIPANAVIPSFSLYGIEELPE Gloin1 D-TGNKVSRKSV-ICGSQNIILGGKTIIQRGDLRRTAIGRYCLLARGSIIRPPYKTYYYPMKIGDHVT-IGEGSIV-EAATIGSFVHIGKNCVIGRFAIIEDNTVIPPNTVVPSFSIYEVDELPE Hisca1 D-TGNKVSRRSQ-VHGTQHIILGGKTVIQRGDLFRQSIGRYTYLSRSCLLRPPSRLHFYPLKIGDHVF-VGEKAVV-EAASVGNHVHIGREAVIGSMAIVLDGAVVPPGMVVPSWCVVGVGEIGE Klula1 G-QGTRISKQAN-VLGPDKIVLAGQCVISEGNVLLMSVGRYCILEPGVRVKPPVVGYHSDLLMNSYVW-IGQDCKV-YCKKLGSRVVLGANTHLNRCCEIDDNLVVPERYKIPSYSRVSVKPLPP Lacbi2 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTSLGRYCLVGEGCVMRPPYKTYYYPMKIGDHVH-IGANSVV-EAATIGNHVEIGKNCVIGKFTIIADNTIVPPNTVIPALALFSVEDLPE Lenti61 D-TGNKVSRRAT-ISGPQNIILGGKTIIARGDLRRTSLGRYCLIGEGCVMRPPYKTYYYPMKIGDHVH-IGANSIV-EAATIGNHVEIGKNCIIGKFTIIADNTVIPPNTVVPALALFAIEDLPE Malgl1 ------------------------------------------------------------MRLGDYVR-IGAHSIV-EAAQIGSHVDIGERCVIGRFCVILDGAVLAPHTVVPSHCIFAVGMLPE Mellp23 D-TGNKVSRKAL-ISGSQNIILGGKTIIQRGDLRRSGIGKFCLLGERSVIRPPYKTYYYPMKIGDHVH-IGSDSVI-EAASIGNLVNIGKNCVIGRFSIIADNTIIPPGTVIASMSYYSQSDLPE Mnele A-NNNKVSRQSV-LCGSQNIVLGGKTIIQRGDLANVRFGRQCVIGSKSVIRPPFKKFFFPFQMGDHVM-VGEGSIV-NAASIGSYVNIGKNVVIGRRSFIADNSVLPPETVVPPFTLWAVAELPE Monbr ----------------------------------------------------------------------------------------------------------------------------- Morel2 D-TGNKVSRKSV-ICGSQNIILGGKTILQRGDLRRTSVGRYCFLSQGCVIRPPSKTYYYPMKIGDHVT-IGEGTIV-QAATIGSFVSIGKNCVIGRFAIIEDNTVIPPNSVVPSFSVYKVDELPE Mucci2 D-TGNKVSRKSV-ICGSQNIILGGKTIIQRGDLRRTAIGRYCLLSQSSVIRPPYKTYYYPMKIGDHVT-IGEGSIV-EAATIGSHVNIGKNCIIGRFAIITDNTIIPPNTVVPSFSVYSQDELPE Mydma A-SGNKVSRQSV-LCGSQNIVLNGKTIIMRGDLANVRIGRHCVISQRSVIRPPFKRFFFPLHIGDHVF-IDEDSII-NAAQIGSFVYIGKNCIIGRRCIIADNTVLPPDTVVPPFTIMAVGELPE Neucr2 D-TGNKVARKAT-LVGTQNIMLGGKTVIQRGDLARTAIGRYCFLSRGCCLRPPGRMYFMPLRLGDHVF-VGPGTVV-QAAQIGNHVHIGGKVVIGEFAIVLDGSVVPPNMVIPSFSIVAIGEIPE Orpsp11 D-SGNKISRKSV-ISVPQNIVLGGKTIIQRGDLRRKGIGKYCLLGENSIIRPPYKIYYYPMKISDYVH-IGKRTIV-EAARIGQYVIIGNDCVIGRFSVILDNTVIPPNTVIPSFSVYGISELPE Pench1 D-TGNKISRRSQ-IHGTQHIILGGKTVIQRGDLFRTTVGRYSYISKSAILRPPSRLHFYPLKIGDHVF-VGEGAVV-EAASLGNHVHVGKGAAVGSMAIVLDGAVVPPGMVVPSWCIVGVGEVGE Phybl2 D-TGNKVSRKSV-ICGSQNIILGGKTIIQRGDLRRTAIGRYCLLAQGSIIRPPYKTYYYPMKIGDHVT-IGEGSII-EAATIGSYVTIGKNCIIGRFAMITDNTVIPPNTVVPSFSVYSQDELPE Picst3 S-SGNRISRSAH-ISGSDRIVINGNATIHHGDVQLLTLGKFCYLRPNCQIIPPVLQEHGPVTIGAYTI-IGSNTVV-KLANVGNRVLIEDDCVLENLSIIRKGTVVPPKTIIPPYSEVSISSLNS Plicr1 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTSLGRYCLVGEGCVMRPPYKTYYYPMKIGDHVH-IGANSVV-EAATIGNHVEIGKNCIIGKFTIVADNAVIPPNTVIPALSLFSVEDLPE Polpo L-NGNKVSKKSI-LCGIMNIRLHGKTIIKRGDLANVNIGRLSIVEENTVIRPSYKKFYFPLNIGDHVI-IKEDTVI-SAATIGS---------YSKRCIIPDNTILPPDTVVPPFTIYQKEELPD Pucgr2 D-TGNKVSRKAL-ISGSQNIILGGKTIIQRGDLRRAGIGKFCLLSERSVIRPPYKTYYYPMKIGDHVH-IGADTIV-EAASIGNLVEIGKNCVIGRFAIIADHTIIPPGTVVASMSLYSQADLPE Punst1 D-TGNKVSRRAT-IAGPQNIILGGKTIIARGDLRRTSLGRYCLVGEGCVMRPPYKTYYYPMKIGDHVH-IGANTVV-EAATIGNHVEIGKNCVIGKFTIIADNTVVPPNTVIPALSLFAVEDLPE Rhior3 ----------------------------------------------------------------------------------------------------------------------------- Rhoto1 D-TGNLVSRSCV-ICGSSNIVLGGKSILQRGDLRRAAMGKYCNVGEGTVLRPCYKTYYYPMKIGDYVT-IGANSVV-EAASIGNGVEIGKGCIIGPLAIIADGAVVGAGTIVPSLTEWAVGQLPE Rozal11 D-SGNKISRKST-IYGSQSITIAGKTIVNRGDLKKQSIGKYCYISKGVKIIPPARLVFYPIRIGDHVY-IGENSQV-KASSIGSNVYIGKNCVIGEFVVINDNTTISPHAVIPSWTVWYSDDFLA Sacce1 ----------------------------------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------------------------------- Schco3 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLRRTSLGRYCLVGEGCVMRPPYKTYYYPMKIGDHVH-VGANTIV-EAATIGNYVEIGKNCVIGKFTIIADNTIIPPNTVIPALALFGLEDLPE Schpo1 ----------------------------------------------------------------------------------------------------------------------------- Sorma D-TGNKVARKAT-LVGTQNIMLGGKTVIQRGDLARTAIGRYCFLSKGCVLRPPGRMYFMPLRLGDHVF-VGPGTVV-QAAQIGNHVHIGGKVVIGEFAIVLDGSVVPPNMVIPSFSIVAIGEIPE Sphar I-KGIKVSRRAN-LRGLGNLRTGDQNVFSRGDLALITTGRNVFLGTNSVLQPPHKLFYYRQQIGSHVV-IGRECVV-NAAAIGSYVRIGNDVIIGQGCVIEDGAVLPPDMVVAPFSVVGIGRCVD Spipu1 D-TGNKVSRKSV-ICGSQNIVLGGKTIIQRGDLRRTAIGRYCLLSQRCILRPPYKTYYYPMKIGDHVV-IGEDSVV-EAAQIGSHVHIGKDCVIGRFVIILDGTVIPPNTVIPSFSVYGVDELPE Sporo1 E-TGNIVSRQSL-IYGSQNIVLSGKSILSRGDLKRTAMGKYCFVGESTVLRPCYKTYYYPMKIGDYVT-IGSSCVV-EAASIGNGVEIGKNCIIGPLAIISDGAIVGAGTIVPSLTEWSIGQLAE Stehi1 D-TGNKVSRRAT-IAGPQNIILGGKTIISRGDLKRTSLGRYCLVGEGCTMRPPYKTYYYPMKIGDHVH-IGANTVV-EAATIGNHVEIGKNCVIGKFTIIADNTIVPPNTVIPALSLFSVEDLPE Tapde11 E-SGNHISRAGLNLINTQSIVLGGKTVIERGDLRRPTLGRYCLVGRGTSLVPPHRVRWYPLKVGDYVH-VGAHSTV-SAASIASCVHIGAHCVIGNMSIIEDGSVLPPYTVVAPFSRVSVGECPE Thetr A-SGNKVSRASV-LCGSQNIILNGKSLVLRGDLAAVRIGRYCVISDRVVLRPAYKALYFQLSLGDCVY-VGKDAVV-EAASIGSHVIIGEGAIVSKRAVILPGAVVPEDAVIPPFSIYGIGELTE Treme1 D-TGNKVSRKAS-IVGASNIILGGKSIIQRGDLRRTTMGRYCVIGENTIIRPPSRFYYYPVKMGDFAQ-IGKNCII-EAATIGSGSEIGDNCIIGKFTVIKPNTVLPENTQVASYTIWAIGTLPE Trire2 D-TGNKVARKAV-LVGTQNIMLGGKTVIQRGDLVRTAIGRYCFLSRAVLLRPPGRIYYMPLRIGDHVF-IGQGTVV-QAASIGNHVSIGSGCVVNEFAIVLDGTIVPANMVIPSFSIVAVGELPD Umbra1 D-TGNKVSRKSV-ICGSQNIILGGKTIIQRGDLRRTAIGRYCLLAHGSIIRPPYKTYYYPMKIGDHVT-IGEGSIV-QAATIGSYVTIGKNCVIGRFAIIADNTIIPPNTVVPSFSIYDRDELPE Ustma22 ALTGNKVSRKAT-ILGSQNIILGGKCIIQRGDLKRIFIGRYCILAESSVIRPPYKTYYYPMKMGDHVS-VGANTVL-EAASVGSHVEIGANCLVGRFVIILDGSVVAPNTVIPSFSIFGVGELPE Walse1 D-TGNRISKKAV-ICAPVNIILSGNVIIKRGDLRRTSIGKFTILDDGCIIRPAYKTYYYPMKIGDFTT-IGSQTIL-EAAQVGSYVEIGRNCVIGRFVVVAPNSVIPPNTVIPPYALFSIDTLPE Zygro1 ----------------------------------------------------------------------------------------------------------------------------- [Cluster2650.fasta_al_trimmed; alignment length = 311] Allma1 MSHFGTLFRVSTFGESHCKGVGCIVEGVPPGLPLTEDDVQPQLTRRRPGQSALTTPRDEKDRVTILSGTEGVTLGTPIGLFVPNQDQRPGDYDLYPRPSHADYTYLQKYGVKASSGGGRSSARETIGRVAAGAIAEKYLALAHGVEIVAFTSSIGLLSTVTRTDVDDSIGGTVTCVIRNPPVGLGEPCFDKLEASLAHAMLSIPATKGFEIGSG--FAGGSVHNDAWTRTNYSGGIQGGISNGEAIYFTVAFKPAATIGQEQKTTRYDGGTLAARGRHDPSVVPRAVPIVEAMAALVIMDALLVQNSRRAA Ashgo11 MSSFGQVFRVTTYGESHCKSVGCIVEGVPPGLSLTEEDIQPQLTRRRPGQSKLSTPRNEKDRVEIQSGTEGRTLGTPIGMLVKNEDQRPHDYDDFPRPSHADFTYIEKYGIKASSGGGRSSARETIGRVAAGAIADKFLQQACGVEIVAFVSQIGLLNTITREQVDDSIGGVVTCVVRNVPTGLGEPCFDKLEAKLAHAMLSIPASKGFEIGSG--FAGGSKHNDPFTRTNNSGGVQGGISNGEHIYFSVPFKSAATISQAQATATYAGGVLAAKGRHDPSVTPRATPIVEAMTALVLADAFLLQKAREAA Aspfu1 MSTWGEYFRVTTYGESHCRSVGCIVDGCPPGMELTEEDIQPQMTRRRPGQSALTTPRNEKDRVEIQSGTEGITLGTPIGMMVRNEDQRPKDYDLYPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLRLSHGVEIVAFVSSVGLIETIDRKTVDDSIGGTVTCVIRNVPVGLGEPCFDKLEAKLAHAMLSIPATKGFEIGSG--FGGGSIHNDPFTKTNNSGGIQGGISNGAPIYFRVAFKPPATIGQAQTTASYSFGILEAKGRHDPCVTPRAVPIVEAMSALVVMDALMAQYARESA Aurde31 MSTFGTLFRVTTYGESHCASVGAIIDGCPPGMPLEAADIQVQMNRRRPGQSNLTTPRNEKDAIQLQSGIEGVTLGTPIGLYVRNEDQRPHDYDLFPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLRMAYGIEIVAFVTSVGLLSTVSREQVDDSIGGTVTCVIRNVPSGLGEPVFDKFEAKLAHAMLSIPATKAFEVGSG--FRGGSKHNDAFTATNWSGGIQGGITNGESIYFRVGFKSPATISQAQETARYDGGTLAARGRHDPCVVPRAVPIVEAMAALVVIDQLLIQNSRRAA Batde5 MSSFGSFFRISTFGESHCKAVGVIVDGCPPGLPLSENDVQPLLDRRRPGQSVLTTPRDEKDRVVILSGTEGFTLGTPIAMMVPNQDQRPHDYDLYPRPSHADWTYLQKYGVKATSGGGRASARETIGRVAAAAVAEKYLKSAHGIEVVAFVASVGLLKNITRKDVDDSIGGSVVCVIRNVPAGLGEPCFDKLEAQLAHAMLSIPATKAFEIGSG--FSGGHVHNDPFTTTNFSGGIQGGISNGEDIYFRVGFKPAATIGISQETTSYEGGILAAKGRHDPCVLPRAVPIVEAMASLVVMDMLLAQGSRKSA Botbo1 MSTFGTLFRVTTYGESHCASVGCIVDGVPPGLRLTDADIQVQLSRRRPGQSNLTTPRDEKDLVRLQSGIEGVTLGTPIGLLVQNQDQRPHDYDFYPRPSHADWTYLQKYGIKASSGGGRSSARETIGRVAAGAIAEKYLKEAHGVEIVAFVSSVGLLKTITREIVDDSIGGTVTCVIRNVPSGLGEPVFDKLEAHLAHAMLSIPATKAFEVGSG--FKGGSRHNDAFTTTNWSGGIQGGISNGQDIYFKVGFKSPATISKEQATAQYDGGTLAARGRHDPCVVPRAVPIVEAMAALVLMDQLFIQNSRVAA Botci1 MSTFGQYFKVTTYGESHCRSVGCIVDGVPPGMELTEADIQPQMTRRRPGQSALTTPRDEKDKVEIQSGTEGITLGTPIGMIVRNQDQRPHDYDLYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAASAIAEKYLRLAHGIEIVAFVSSVGLIQDVTRERVDDSIGGTVTCVIRNVPSGLGEPCFDKMEAMLAHAMLSIPASKGFEIGSG--FGGGSKHNDPFTKTNNSAGIQGGITNGAPIYFRVAFKPAATIGQAQETATYDGGILEAKGRHDPCVVPRAVPIVEAMAALTVIDALMAQQARQTS Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MSSFGTLFKVTTYGESHCKSVGCIVDGCPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDLVEIQSGTEGLTLGSPIGMIVRNKDHRPGDYDLYPRPSHADWTYIQKYGTKSSSGGGRSSARETIGRVAAGAIAEKILAKVNNVEIVAFVSAIGLLNTITREQVDDSIGGVVTCVIRNCPIGLGEPCFDKLEAKLAHAMLSLPATKGFEFGSG--FEGGSKHNDAFTETNNSGGIQGGISNGENIYFSVAFKSAATISQEQETATYDGGVLAARGRHDPSVTPRAVPIVEAMTALVLCDEYMIQQARTST Cangl MSTFGRLFKVTTYGESHCKSVGCIVDGVPPGLTLEEKDIQPQLTRRRPGQSALSTPRNEKDRVEIQSGTEGKTLGTPIAMIVRNEDHKPKDYDNYPRPSHADFTYSEKYGIKASSGGGRASARETIGRVAAGAIAEKFLHYVSEVEIVAFVTQIGLLNTITREQVDDSIGGVVTCVVRNLPTGLGEPCFDKLEALLAHAMLSIPASKGFEIGSG--FEGGSKHNDPFTKTNNSGGVQGGISNGENIYFSVPFKSVATISQEQKTATYDGGVLAAKGRHDPAVTPRAIPIVEAMTALVLADAVLIQKAREYS Capow MSTFGTLFRVTTFGESHCAGVGCIVDGVPPLMALTEADIQPQLSRRRPGQSALTTKRDEKDLVRIMSGTEGVTLGTPIGLTVPNEDMRPGDYSDIPRPSHADYTYQYKYGTKTSSGGGRASARETIGRVAAGAIAEKFLRLRYGVEIVAWVSSIGVVDTITRERVDDSVGGVVSCVIRNSPVGLGEPCFDKLQATLAHAMMSIPATKGFEIGSG--FRGGSAHNDMFTVTNNSGGVQGGISNGEPIVLRVAFKPPATIGKEQATVTYDGAVLAAKGRHDPCVVPRAIPIVEAMAALALADAALVQLSRHAA Catan2 MSSFGNIFRVTTFGESHCKGVGCIVEGVPPGLPLTEDDIQPQLTRRRPGQSALTTPRDEKDRVSILSGTEGTTLGTPIGLFVPNQDHRPGDYDLYPRPSHADWTYLQKYGVKASSGGGRSSARETIGRVAAGAIAEQYLKIAHGVEIVAFTSAIGQLAEVTRANVDDSIGGVVTCVIRNVPVGLGEPCFDKLEASLAHAMMSIPATKAFEVGSG--FAGGSKHNDPWTSTNYSGGIQGGITNGENIYFRVAFKPAATIGQEQNTATYDGGVLKARGRHDPCVVPRAIPIVEAMAALVIMDAVMQQNARKSA Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MSTFGTHFRVTTYGESHCLSVGAIIDGCPPGMALTEADIQPQMTRRRPGQSAITTPRNEKDRVEIQSGTEGITLGTPIGIRVMNENQRKQDYDKYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLREAYGIEIVAFTNSIGLVDTITREKVDDSIGGTVACVIRNCPTGLGEPCFDKLEAKLGHAMLSIPATKGFEIGSG--FGGGSIHNDPFTKTNNSGGIQGGISNGAPIYFNVAFKPAATIGQAQSTVTYDQGILEAKGRHDPCVVPRAVPIVESMAALVIMDAVLAQQARQGA Coere1 MSTFGKAFRVTTYGESHCKSVGCIIDGVPPGLALTENDIQVQLTRRRPGQSNLTTPRNEKDRVAIESGCEGYTLGTPICLTVQNQDQRPHDYDFYPRPSHADWTYLQKYGVKASSGGGRSSARETIGRVAGGAVAEKYLSEVYGVEIVAFVSSVGLLATITREQVDNSTGGIVTCVIRNAPVGLGEPCFDKLEAMLAHAMLSIPATKGFEVGSG--FSGGSEHNDAFTKTNHSGGIQGGISNGESIYFRVAFKPPATISQDQQTATYAGGILAARGRHDPCVVPRAVPIVETMAALTIMDAVMQQNARSAT Conco1 MSTFGDLFRVTTYGESHCPSVGCIIDGVPPGMGLTEDDIQPQLTRRRPGQSNLTTPRNEADAVTIHSGVEGITLGTPIALQVKNKDQRPHDYDLYPRPSHADWTYLLKYGVKASSGGGRSSARETIGRVAAGAVAEKYLRQVYGTEIIAFVSSVGLFSTITREEVDDSTGGTVTCIIRNVPSGLGEPCFDKLEAKLAHAMMSIPATKGFEIGSG--FKGGSQHNDMWTITNLSGGIQGGISNGENIYFRIAFKPPATISQAQNTASYTGGILSTRGRHDPCVVPRAVPIVEAMAALVLTDMALIQSSRKAA Conpu1 MSTFGTLFRVTTYGESHCASVGAIVDGCPPGLQLSAEDVQVQLSRRRPGQSNLTTPRNEKDAVHIQSGIEGVTLGTPIGLLVKNEDQRPHDYDLYPRPSHADYTYLQKYGVKASSGGGRSSARETIGRVAAGAIAERYLKEVYGVEIVAFVSSVGLLATITREEVDDSIGGTVTCVIRNVPSGLGEPVFDKFEAKLGHAMLSIPATKAFEIGSG--FRGGSRHNDAFTATNWSGGVQGGITNGEDIYFRIGFKSPATISQAQATAQYDGGELAARGRHDPCVVPRAVPIVEAMAALVVMDQLLIQGARRSA Copci MSTFGTLYRVTTYGESHCASVGAIIDGCPPGLELSAEDIQIQLSRRRPGQSNLTTPRNEKDLVQLQSGLEGVTLGTPIALLVKNEDQRPHDYDLYPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKQAFGIEIVAFVSSVGLLKTITREEVDDSIGGTVTCVIRNVPAGLGEPVFDKFEAALAHAMLSIPATKAFEVGSG--FRGGSKHNDPFTVTNWSGGIQGGITNGEDIYFRIGFKSPATISQPQETARYDGGTLAARGRHDPCVVPRAVPIVEAMAALVVMDQLLQQDARKTA Croqu1 MSTFGTLFRVSTAGESHCSGITAIVDGVPPGLELKEEDLQAQLSRRRPGQSNLTTPRNESDLVRIQSGVEGVTLGTPISLFVPNKDQRPHDYDLYPRPSHADWTYLLKYGIKASSGGGRSSARETIARVAAGAIAEKFLKLAYGIEIVAFVSSVGYLSNLTRADVDDSIGGTVTCVIRNCPTGLGEPCFDKLEAKLAHAIMSIPATKGFEIGSG--FRGGSVHNDMFTVTNRSGGIQGGISNGENVYFRCAFKSPATIAQAQPTATYSGGVLAARGRHDPCVVPRAVPIVEAMAAMVIMDAVLQQNARKSV CryneH991 MSSFGTLYRVHTYGESHCKSVGCIVDGVPPGLQLTEADIQTQLSRRRPGQSDITTARSEFDTVHVQSGTEGVTLGTPIGLLVHNKDQRPHDYDLYPRPSHADYTYLAKYGVKASSGGGRASARETIGRVAAGAIAEKYLKEAFGVEIVAFVASVGLVKTITREEVDDSLGGSITCVIRRCPLGLGEPCFDKLEAVLAHAMLSIPSTKSFEIGSG--LRGGSLHNDPFTVTNWSGGVQGGISNGEDIYFRIGFKPPATIAQEQPTARYDGGVLAAKGRHDPCVVPRAVPIVETMAALVIMDMVLQQNARLTA Crypa2 MSTFGEYFRVTTYGESHCRSVGCIVDGCPPGMALTEADIQPQMTRRRPGQSAITTPRNEKDRVQIQSGTEGVTLGTPIGMLVMNEDQRPKDYDLYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLRLAYGVEIVAFTTSVGLLQTIDRKTVDDSIGGTVTCVIKNAPTGLGEPCFDKLEALLAHAMLSIPATKGFEIGSG--FGGGSIHNDPFTKTNFSGGIQGGITNGAPIYFRVGFKPAATIGQEQTTATYDGGILAAKGRHDPCVVPRAVPIVESMAALVLMDTVLAQQARSTA Debha1 MSTFGNIFRVTTYGESHCKSVGCIVDGCPPGLALTEDDIQPQLSRRRPGQSKLSTPRNEKDQVHIQSGTEGLTLGSPIGMLVQNEDHRPHDYDLYPRPSHADWTYIQKYGVKSTSGGGRSSARETVGRVAAGAIAEKILTKANNVEIVAFVSSIGILNTITREEVDDSIGGVVTCVVRNCPIGLGEPCFDKLEAQLAHAMLSLPATKGFEFGSG--FLGGSVHNDPFTVTNNSGGIQGGISNGENIYFSVAFKSAATISQEQYTSTYDGGVLAARGRHDPSVTPRAVPIVEAMTALVLVDQLLTQKAREYG Dekbr2 MSTFGTLFKVTTYGESHCKSVGCIVDGVPPNMSLTEEDIQPQLSRRRPGQSKLSTPRNEKDRVYIQSGTEGKTLGTPIGMLVLNENQRPKDYAKYPRPSHADYTYIEKYGIKASSGGGRASARETIGRVAAGAIAEKFLKQANNVEIVAFVSGVGLLQNITRETVDDSIGGIVTCVVRNVPIGLGEPAFDKLEAMLAHAMLSIPATKGFEIGSG--FAGGSKHNDPFTTTNNSGGIQGGISNGENIYFSVAFKSPATISKPQSTATYDGGTLEAKGRHDPNVVPRAVPIVEAMTALALADSYLIQKSREST Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MSSLNTLFRVTTFGESHGDAVGCVIDGVPPGLLIPAAAVQRQLDRRRPGQSHLVTPRNEPDRVRILSGLDGRSLGTPLAMMIDNQDARPQDYDAAPRPSHADYTYRCKYAVPSASGGGRASARETAARVAAGAVADLWLAGAFGVEVVAYVEAVG----FTRAQVDDSVGARLAVRVRGLPAGWGEPVFDRLPARLAHAALSLPAARGFAMGRDGWHRAGSRWNDPFPATNQSAGSQGGLTTGLPLSFRVAMRPPSTIARAQRTADWAGREVAGAGRHDPCVGPRAVPILEAMTSLVLADLALIQLSRQAA Fomme1 MSTFGTLFRVTTYGESHCASVGCIVDGCPPGLQLTAADIQVQLSRRRPGQSNLTTPRDEKDLVHVQSGVEGVTLGTPIGLLVKNEDQRPKDYDLYPRPSHADYTYLEKYGIKASSGGGRSSARETIGRVAAGAIAETYLRQVYGIEIVAFVSSVGLLSTVTRAAVDDSIGGTITCVMRNVPPGLGEPVFDKFEAALAHAMLSIPATKAFEIGSG--FRGGSRHNDAFTRTNWSGGVQGGITNGQDVYVRVGFKSPATISQAQSTAQYDGGELAARGRHDPCVVPRAVPIVEAMAALVIMDMLLMQNARSQA Fusgr1 MSSFGQFFRVTTAGESHGKSVSCIIDNCPPNLGLTEADIQPQLNRRRPGQSAITTPRNEKDRVTIHSGTEGVTLGTPILLTVPNEDQRPKDYDLYPRPSHADWTYLEKYGTKASSGGGRSSARETIARVAAGAVAEKWLKEAYGIEIVAFVTSVGLAERITRQEVDDSTGGTVTCVIRNAPSGLGEPCFDKLQATLAHAMMSIPAVKAFELGSG--FQGGSKHNDPFTKTNHSGGIQGGISNGMPIFFKVGFKPPATISQDQTTARYDGGILSAKGRHDPCVVPRAVPIVEGMAALVIADAIMAQHARQMA Galma1 MSTFGTLFRVTTYGESHCASVGAIIDGCPPGLELSAQDIQVQLSRRRPGQSDLTTPRNEKDFVQLQSGIEGVTLGTPIALLVKNEDQRPHDYDLYPRPSHADYTYLQKYGIKASSGGGRSSARETIGRVAAGAIAEKYLKIVYGIEIVAFVSSVGLLSTISRDEVDDSIGGTVTCVIRNVPSGLGEPVFDKFEASLAHAMLSIPATKAFEIGSG--FRGGSQHNDPFTTSNWSGGIQGGITNGENVYFRIGFKSPATISQAQDTAKYDGGSLAARGRHDPCVVPRAVPIVEAMAAIVVMDQLLIQNSRKTA Ganpr1 MSTFGSLYRVTTFGESHCAAVGVVIDGVPPGVPLGVEDIQPQLNRRRPGQTNLTTPRDEKDRVNILSGTEGYTLGTPVALMVKNEDQRPGDYNLYPRPSHADWTYLLKYGVKASSGGGRSSARETIGRVAAAAVAEKYLTLAHGVEIVAFVASVGLLKGVSRADVDDSIGGTVVCVIRNLPPGLGEPCFDKLEAKLAHAMLSIPATKGFEIGSG--FAGGHVHNDPFTKTNFSGGIQGGISNGENIYFRVAFKAAATISQSQHTATFDGGVLAAKGRHDPCVLPRAVPIVEAMASLAVMDALLLQLSRKAA Gloin1 MSTFGTLFRVTTFGESHGKSVGCIVDGCPPGLSLVEADIQIQLDRRRPGQSNLTTPRDEKDKVAIQSGTEGITLGTPIGLLVPNQDQRPHDYDLYPRPSHADWTYLQKYSIKASSGGGRASARETIGRVAAGAIAEKYLKLVHGVEIVAFVSSVSLLNTIRREEVDDSVGGTITCVIRNVPVGLGEPCFDKLEAKFAHAMLSIPATKGFEIGSG--FKGGHQHNDPWTKTNNSGGTQGGITNGENIYFRVAFKPPATISQEQETATYNGGVLAARGRHDPCVVPRAVPIVESMAALVIMDALMIQQSRKTV Hisca1 MSTFGEYFRVTTYGESHCRSVGCIVDGCPPGMALTEEDIQPQMTRRRPGQSALTTPRNEKDKVEIQSGTEGITLGTPIGMVVRNEDQRPKDYDLYPRPSHADFTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLNLSHNIEIVAFVSSVGLIANIDRPTVDDSIGGTVTCVIRNVPVGLGEPCFDKLEAKLAHAMLSIPATKGFEIGSG--FLGGSIHNDPFTKTNNSGGIQGGISNGASIYFRVAFKPPATIGQAQTTASYDFGVLEAKGRHDPCVVPRAVPIVESMASLVVIDALMAQNAREAA Klula1 MSTFGQIFRVTTYGESHCKSVGCIVDGVPPGMSLTEDDIQPQLTRRRPGQSKLSTPRNEKDRVEIQSGTEGKTLGTPIGMLVKNEDQRPHDYDNYPRPSHADFTYSSKYGIKASSGGGRSSARETIGRVAAGAIAEKFLKQLSNVEIVAFVTQIGVLNTITREKVDDSIGGVVTCVIRNLPAGLGEPCFDKLEALLAHAMLSIPASKGFEIGSG--FDGGSKHNDPFTKTNNSGGIQGGISNGENIYFSVPFKSAATISQEQATATYDGGILAAKGRHDPSVTPRATPIVEAMAALVLADAVLIQKSREAA Lacbi2 MSTYGSLFRVTTYGESHCASVGAVVDGCPPGLQLSAADIQVQLSRRRPGQSNLTTPRDEKDLIHLQSGLEGVTLGTPIAFLVKNEDQRPHDYDLYPRPSHADYTYLEKYGIKASSGGGRSSARETVARVAAGAIAEKYLKLAYGIEIVAFVSSVGLLATISREQVDDSIGGTVTCVIRGIPSGLGEPVFDKFEASLGHAMLSIPATKAFEIGSG--FRGGSKHNDPFTATNWSGGVQGGITNGEDIYFRIGFKSPATISQSQETAQYDGGSLAARGRHDPCVVPRAVPIVEAMAAIVVMDQLLIQNSRKTA Lenti61 MSTFGTLFRVTTYGESHCASVGAIIDGCPPGLPLVAQDVQTQLSRRRPGQSNLTTPRDEKDLVQLQSGTEGITLGTPIGLLVRNEDQRPKDYDLYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKLAYGVEIVAFVSSVGLLKTVTREKVDDSIGGTVTCVIRNVPSGIGEPVFDKLEAKLAHAMLSIPATKAFEIGSG--FRGGSKHNDAFTRTNWSGGVQGGISNAEDIYFRVGFKSPATISQAQATAQYDGGTLAARGRHDPCVVPRAVPIVEAMAALVIMDQVLIQNARKTA Malgl1 MSTFGSTYRVSTFGESHCKAVGCIVDGIPPGLAVSEQDIQRQLTRRRPGQSSLTTPRDEKDKVEILSGTEGVTLGTPVAMMVRNQDQRPHDYDAIPRPSHADYTYLEKYNVKASSGGGRSSARETIGRVAAGALAEKYLTDVLGIEIVAFVSSVGLLNNVTRDQVDDSIGGTVTCVIRNVPVGLGEPSFDKMEAKLAHAMLSIPATKGFEIGSG--FRGGSKHNDPFTSTNWSGGIQGGITNGEHIYFRVAFKPPATISQEQNTARYDGAVLENRGRHDPCVVPRAVPIVESMAAIVIMDMFLAQSARKSA Mellp23 MSTFGTLFRVSTAGESHCSGITA----------------NFQVSRRRPGQNNFTIP-NESDLVKIQSGVEGVTLGTPISLFVPNKDQRPHDYDLYPRPSHADWTYLLKYGIKASSGGGRSSARETIARVAAGAIAEKFLKLAYGIEIVAFVSSVGYLSTVTRADVDDSIGGTVTCVIRNCPTGLGEPCFDKLEAKLAHAIMSIPATKGFEIGSG--FKGGSVHNDMFTVTNRSGGIQGGISNGENVYFRCAFKSPATIAQAQSTATYAGGVLAAKGRHDPCVVPRAVAIVEAMAAIVMMDAVLQQNARKSL Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr MSTFGTYFRVTTFGESHCKGVGAIVDGVPPRLALTEEDVQPQLTRRRPGQSKLTTPRNESDRVTIMSGTEGRTLGTPIGLFVPNQDQRPKDYSHAPRPSHADFTYMSKYGTHASSGGGRSSARETIGRVAGGAIAEKWLREAFGIEIVAWVSAVGDVDTITREQVDDSTGGVVSCVCRNVPAGWGEPCFDKLEAKLAHAMMSIPATKGFEVGSG--FSGGSTHNDLFTATNNSGGIQGGISNGENIVFRIAFKPPATIGQQQQSVNFQGDVVAAKGRHDPCVVPRAIPIVEAMAALVLADLALAQLARRSA Morel2 MSTFGTHFRVTTFGESHCKGVGCIIDGCPPGLALTEDDIQPQLTRRRPGQSNLTTPRDEKDRVTILSGTEGHTLGTPIGLTVPNQDQRPHDYDLFPRPSHADWTYLLKYGLKASSGGGRASARETIGRVAAGAVAEKFLKEAYGTEFIAFVSSVGMLSTVTREQIDDSIGGTVTCVIRNVPTGLGEPCFDKLEAKLAHAMLSIPATKAFEIGSG--FGGGHLHNDAWTKTNFSGGIQGGISNGENIYFRIGFKSPATISQEQQTTSYGGGVLATRGRHDPCVVPRATPIVEAMAALVIMDAVMIQLARQGA Mucci2 MSSFGKLFRVTTFGESHCKGVGAIIDGVPPGMELTEADIQPQLTRRRPGQNKLTTPRDEKDKVTIMSGTEGVTLGTPIGIQVPNLDQRPHDYDIYPRPSHADYTYLQKYGLKASSGGGRASARETIGRVAAGAIAEKYLRLAYGVEIVAFASSVGFMNTITRDDVDDSVGGTVTCVIRKCPVGLGEPCFDKLEAILAHAMLSIPATKGFEFGSG--FNGGHDHNDPFTTTNNSGGVQGGISNGENIYFRVAFKPAATISQDQTTANYDGGTLAAKGRHDPCVVSRAVPIVEAMAALVIMDAALQQESRRTA Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MSTFGHYFRVTTYGESHCKSVGCIVDGVPPGMELTEDDIQPQMTRRRPGQSAITTPRDEKDRVIIQSGTEGVTLGTPIGMLVMNEDQRPKDYDIYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKLAYGVEIVAFVSSVGLVNSITRETVDDSIGGTVTCVIRNVPSGLGEPAFDKLEAMLAHAMLSIPATKGFEVGSG--FGGGSIHNDPFTKTNFSGGIQGGISNGAPIYFRVGFKPAATIGQEQTTATYDGGVLAAKGRHDPSVVPRAVPIVEAMAALVIMDAVLAQQARHTA Orpsp11 --------------------------------------------------------RDEKDRVTIYSGTEGYTLGTPIGLMVSNTDQRPNDYIIYPRPSHADYTYLEKYTLKATSGGGRASARETIGRVAAGAIAEKYLKEAFGIEIVSFVSSVGLIENVTREQVDDSIGGTLVCVIRNVPAGLGEPCFDKLEAQLAQAMLSLPATKGFEIGSG--FAGGHIHNDPFTTTNYSGGIQGGISNGETIYFRVAFKPVATIGQAQKTCTYDGGELAAKGRHDPCVVSRAVPIVETMSALVIMDNLLIQLSRQAA Pench1 MSTWGQYFRVTTYGESHCRSVGCIVDGCPPGLEITEADIQPQMTRRRPGQSALTTPRDEKDRVEIQSGTEGVTLGTPIAMVVRNEDQRPKDYDLYPRPSHADFTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKFLSLAHNIEIVAFVSSVGLIETIDRKTVDDSIGGTVTCVIRNVPVGLGEPCFDKLEAKLGHAMLSIPATKGFEIGSG--FGGGSIHNDPFTKTNNSGGIQGGISNGASIYFRVAFKPAATIGQAQTTTSYDGGVLEAKGRHDPCVTPRAVPIVEAMSSLVVMDALMAQYAREGA Phybl2 MSTFGKLFRVTTYGESHCKGVGAIVDGVPPGMELTEADIQPQLSRRRPGQSKLTTPRDEKDKVTIMSGTEGVSLGTPIGIQVPNLDQRPHDYDVFPRPSHADYTYLKKYGLKASSGGGRASARETIGRVAAGAIAEKYLRLAHGVEIVAFTSSVGFLNTISREQVDDSIGGTVTCVIRNCPIGLGEPCFDKLEALLAHAMLSIPATKGFEFGSG--FSGGFQHNDAFTATNHSGGVQGGISNGENIYFRVAFKPAATISRDQQTTSYDGGTLSTRGRHDPSVVPRAVPIVEAMAALVIIDACLQQDAREAS Picst3 MSSFGTLFRVTTYGESHCKSVGCIVDGVPPNLELTEDDIQPQLTRRRPGQSKLSTPRNEKDRVEIQSGTEGLTLGSPIAMIVKNEDHRPHDYDLYPRPSHADWTYIQKYGTKSSSGGGRSSARETIGRVAAGAIAEKLLSKANGVEIVAFVSSIGLLNTVTREQIDDSIGGVVTCVVRNCPIGLGEPCFDKLEAKLAHAMLSLPATKGFEFGSG--FLGGSKHNDPFTTTNFSGGIQGGISNGENIYFSVAFKSAATISQEQPTATYDGGVLAARGRHDPSVTPRAVPIVESMTALVLADQLLIQKARESG Plicr1 MSTFGKLFRVTTYGESHCASVGAIVDGCPPGLELSPQDIQVQLSRRRPGQSKLTTPRDEKDLVQLQSGIEGVTLGTPIALLVRNEDQRPHDYDLYPRPSHADWTYLQKYGIKASSGGGRSSARETIGRVAAGAIAEKYLKTAYNIEIVAFVSSVGLLGSVTRAQVDDSIGGTVTCVIRGVPAGLGEPVFDKLEAALAHAMLSIPATKAFEIGSG--FRGGSRHNDKFTETNWSGGVQGGITNGEDIYFRVGFKSPATISQAQETVQYDGGSLESKGRHDPCVVPRAVPIVEAMASIVIMDQLLMQNARTST Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 MSSFGTIFRVSTAGESHCSGVTAIVDGVPPGLQLTEDDLQTQLSRRRPGQSDLTTPRNESDLVKIQSGVEGVTLGSPISLFVPNRDQRPHDYDFYPRPSHADWTYLL-------------------TRVAAGAIAEKFLRTAYGVEIVAFVSGVGFLSDITREEVDDSIGGTVTCVIKNCPTGLGEPCFDKLEAKLAHAIMSIPATKGFEIGSG--FKGGSKHNDMFTLTNRSGGIQGGISNGENIYFRCAFKSPATIAKEQQTATYNGGVLAARGRHDPCVVPRAVPIVESMAALVIMDAVLLQNARASF Punst1 MSTFGSHFRVTTYGESHCASVGAIIDGCPPGLLLAQEDIQAQLNRRRPGQSALTTPRDEKDLVHLQSGVEGVTLGTPIALLVKNEDQRPHDYDLYPRPSHADYTYLQKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKTVYGIEIVAFVSSVGLLNTVTRADVDDSIGGTVTCVVRRAPAGLGEPVFDKFEAQLARAMLSIPATKGFELGSG--FRGGSRHNDAFTATNWSGGVQGGITNGEHIYFRVGFKSPATITQAQATAQYDGGTLAARGRHDPCVVPRAVPIVEAMASLVVMDALLAQSARAAA Rhior3 MSSFGRLYRVTTYGESHCKGVGAIIDGVPPGMELTEADIQPQLTRRRPGQSKLTTPRDEKDKVTIMSGTEGVTLGTPIGIMVPNLDQRPHDYDIYPRPSHADYTYLQKYGVKASSGGGRASARETIGRVAAGAIAEKYLRLAYGVEIVAFASSVGFMNTLTREDVDDSIGGSVTCVIRKCPIGLGEPCFDKLEALLAHAMLSIPATKGFEFGSG--FKGGGQHNDPFTTSNHSGGVQGGISNGENIYFRVAFKPAATISQDQTTASYDGGVLAARGRHDPCVVSRAVPIVESMAALVIMDAALQQEARQAA Rhoto1 MSTFGALFRVTTYGESHCASVGAIIDGCPPGMPLTDEDIQPQMTRRRPGQSNLTTPRNEADAVQIQSGVEGVTLGTPIGLLVRNKDQRPHDYDHYPRPSHADWTYLLKYGLKASSGGGRSSARETIGRVAAGTIAERYLKLAYGVEIVAFVSSVGLLSTITREKVDDSIGGTVTCVIRRSPVGLGEPVFDKLEAKLAHAMLSIPATKGFEIGSG--FKGGSEHNDAFTKTNRSGGIQGGITNGEDIYFKIAFKSPATISQEQATAKYDGGVLATRGRHDPCVVPRAVPIVEAMAALVIMDAVLIQNARQTA Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 MSTFGKLFRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDRVEIQSGTEGKTLGTPIAMMIKNEDQRPHDYDKFPRPSHADFTYSEKYGIKASSGGGRASARETIGRVASGAIAEKFLAQNSNVEIVAFVTQIGLLNTITREKVDDSIGGVVTCVVRNLPTGLGEPCFDKLEAMLAHAMLSIPASKGFEIGSG--FQGGSKHNDPFTKTNNSGGVQGGISNGENIYFSVPFKSVATISQEQKTATYDGGILAAKGRHDPAVTPRAIPIVEAMTALVLADALLIQKARDFS Salro MSTFGKYFRVTTFGESHCKGVGCIVDGVPPLLELSEEDIQPQLTRRRPGQSKLTTPRNEADKVSILSGTEGRTLGTPVALFVANKDQKPGDYRHAPRPSHADYTYTTKYGVHASSGGGRSSARET----------------------------------------------------------------------------------GFEIGTG--FEGGSEHNDAFTETNNSGGIQGGISNGESIYFRVAFKPPATIGQAQTSANFSGDVVAAKGRHDPCVVPRAVPIVESMAALVLADAALAQLARQGA Schco3 MSTFGSLYRVTTFGESHCKSVGAIIDGCPPGMRLTDADVQVQLRRRRPGQSALTTPRNEPDLVSIQSGTEGITLGTPIGLMVQNTDHRPHDYDLYPRPSHADYTYLEKYDVKASSGGGRSSARETIGRVAAGAIAEKYLKEVYGIEIVAFVSGVGLLNTVTREEVDDSIGGTVTCVIRGVPSGLGEPVFDKFEAKLAHAMLSIPATKAFEIGSG--FKGGSQHNDAFTRTNWSGGVQGGITNGENIYFRIGFKPPATISQEQATSTYAGGTLAARGRHDPCVVPRAVPIVEAMAAIVVMDMMLIQEARHAA Schpo1 MSSFGTLFKVTTYGESHCKSVGCIVEGCPPGMNLTESDVQVQLTRRRPGQSNLTTPRNEKDKVQIQSGTEGVTLGTPIGMLVLNQDQKPHDYDNYPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLLEAYGVEIVAFVSSVGFLNKITREEVDDSIGGTVTCVIRNVPTGLGEPCFDKLEAKLAHAMMSIPATKSFEIGSG--REGGSKHNDLFTLTNNSGGVQGGISNGENVYFTIGFKSPATIGVEQSTSRYDGGVLAAKGRHDPCVVPRAIPIVEAMAALVVMDAVMIQQSRIAS Sorma MSTFGQYFRVTTYGESHCKSVGCIVDGVPPGMELTEDDIQPQMTRRRPGQSAITTPRNEKDRVIIQSGTEGVTLGTPIGMLVMNEDQRPKDYDMYPRPSHADWTYLEKYGVKASSGGGRSSARETIGRVAAGAIAEKYLKLAYGVEIVAFVSSVGLVNSITRETVDDSIGGTVTCVIRNVPSGLGEPAFDKLEALLAHAMLSIPATKGFEVGSG--FGGGSIHNDPFTKTNFSGGIQGGISNGAPIYFRVGFKPAATIGQEQTTATYDGGVLAAKGRHDPSVVPRAVPIVEAMAALVIMDAVLAQQARHTA Sphar MSHFGRFFRVSTFGESHCKAVGCIVDGVPPQMELSEADIQTQLTRRRPGQSDLTTPRNEADAVSIMSGCEGYTLGTPICMIVHNNDQRPGDYSDVPRPSHADFTYQEKYGIRATSGGGRSSARETIGRVAAAGIAEKWLKLMYGIEIVAYVSAVGTFKNITRADVDDSVGGVVSCVVRGVPTGWGEPCFDKLEALLAHAMLSIPATKGFEIGSG--FEGGSVHNDPFTSTNNSGGVQGGISNGMPINVRVAFKPPATISREQTTCTFDGSSLAAKGRHDPCVVPRAVPIVEAMAALVLADVAMSQLARHA- Spipu1 MSSFGSNFRVTTFGESHCKAVGVIVDGVPPGMPLTEDDVQPQLSRRRPGQSNLTTPRDEKDRVSILSGTEGFTLGTPIAMTVPNQDQRPHDYDYYPRPSHADFTYLAKYGIKASSGGGRSSARETIGRVAAAGVAEKFLKLTHNVEIVAFVASIGTLKTISREQVDDSIGGSIVCVIRNVPAGLGEPCFDKLEAKLAHAMMSIPATKGFEIGSG--FAGGHVHNDPFTKTNFSGGVQGGISNGENIYFKIAFKPPATIGQAQATATYDGGTLAAKGRHDPCVLPRAVPIVEAMSALVIMDALLQQLGRQGA Sporo1 MSTFGQMFRVTTYGESHCASVGAIIDGCPPGMPLSNEDIQPQMTRRRPGQSNLTTPRNEADQVYLQSGIEGVTLGTPIGLLVRNKDQRPHDYDHYPRPSHADWTYLLKYGLKASSGGGRSSARETIGRVAAGTIAERYLKLAYGVEIVAFVSSVGLLHGLTREKVDDSIGGTVTCVIRRSPVGLGEPVFDKLEATLAHAMLSIPATKGFEIGSG--FKGGSVHNDAFTKTNRSGGVQGGISNGEDIYFKVAFKSPATISQEQATAKYNGGVLATRGRHDPCVVPRAVPIVEAMAALVIMDAVLIQNSRAAS Stehi1 MSTFGTLFRVTTYGESHCASVGAIIDGCPPGLELSAKDIQVQLSRRRPGQSNLTTPRDEKDLVHLQSGLEGITLGTPIGLLVKNEDQRPHDYDLYPRPSHADYTYLEKYGVKASSGGGRSSARETIGRVAAGAIAERYLSQAYGIEIVAFVSSVGLLKSVTRAEVDDSIGGTVTCIIRNAPTGLGEPVFDKFEAKLAHAMLSIPATKAFEIGSG--FRGGSRHNDAFTKTNWSGGVQGGITNGEDIYFRIGFKSPATISQAQPTAQYDGGSLAARGRHDPCVVPRAVPIVEAMAALVVMDMMMMQESRKAM Tapde11 GSSFGTIFKVTTAGESHCRSVSCIVEGCPPGMALTEPDVQTQLSRRRPGQSHLTTPRDEKDKVEIHSGTEGVTLGTPIMMLVRNQDQRPHDYDAFPRPSHADWTYLQKYGVKASSGGGRSSARETIGRVAAGAIAEKYLLEAYGIEIVAFVSSVGMLNGITRASVDDSIGGTVTCVIRHVPIGLGEPCFDKMEAKLGHAMLSIPSTKSFEIGSG--FAGGSRHNDAFTVTNNSGGVQGGITNGESIYFRVGFKSPATIGMEQSTATYDGGKLAAKGRHDPCVVPRAVPIVEAMAALVVIDQLLMQLARNES Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MSSFGKLFRVHTYGESHCKSVGCIVDGVPPGLKLTEEDIQVQLSRRRPGQSDITTARSEFDTVHLQSGCEGVTLGTPISLLVLNKDQRPHDYDSYPRPSHADYTYLAKYGVKASSGGGRASARETIGRVAAGAIAEKYLLECYGIEIVAFVQRVGLVKSVKRDQVDDSLGGLITCVIRNCPPGLGEPAFDKLEAMLAHAMLSIPSTKSFEIGSG--LRGGSEHNDPWTSTNWSGGVQGGISNGEDIYFRVGFKPPATIAQEQSTARYDGGVLAAKGRHDPCVVPRAVPIVETMSALVIMDMLLQQNARQAA Trire2 MSTFGHYFRVTTAGESHGRTVSCIIENCPPGLALDESDIQPQLNRRRPGQSAITTPRDEKDRVTIGSGCEGRTLGTPILLTVPNEDQRPHDYDLYPRPSHADWTYLEKYGIKASSGGGRSSARETIARVAAGAVAEKWLREAYGIEIVAFVSSVGLVDSLTREKVDDSIGGTVTCIIRGCPSGLGEPCFDKLEALLAHAMMSIPATKGFEIGSG--FRGGSRHNDPFTKTNHSGGIQGGISNGMPIFFRIAFKPPATISQDQTTARYDAGVLAAKGRHDPNVVPRAVPIVEAMAALTIADALMAQHARQMG Umbra1 MSTFGKLFRVTTFGESHCKGVGAIIDGAPPGMELTENDIQPQLTRRRPGQSKLTTPRDEKDRVTILSGTEGITLGTPIGLQVPNLDQRPHDYDIYPRPSHADWTYLQKYGVKASSGGGRASARETIGRVAGGAIAQKYLKLTNNVEIVAFVSSVGMLNTITQEEVDDSIGGTVTCVIRNCPVGLGEPCFDKLEAIMAHAMLSIPATKGFEFGSG--FQGGHLHNDAFTKTNNSGGVQGGITNGENIYFRVAFKPAATISKDQETASYDGGTLAAKGRHDPCVAPRAVPIVEAMAALVIMDSFLQQQARKAS Ustma22 MSTFGSHFRVTTYGESHCASVGCIVDGVPPGMALAAHDIQTQLSRRRPGQSNLTTPRDEKDRVEIQSGVEGVTLGTPIAMLVRNQDQRPHDYDTYPRPSHADFTYLEKYNVKASSGGGRSSARETIGRVAAGALAEKYLKEAYGIEIVAFVSSVGLLATITRAKVDDSIGGTVTCVIRGVPSGLGEPCFDKLEAKLAHAMLSIPATKGFEIGSG--FRGGSRHNDKFTITNWSGGIQGGISNGEDIYFRVGFKSPATISQNQSTATYDGGTLNTRGRHDPCVVPRAVPIVEAMAALVVMDAVLVQSGRDKA Walse1 MSTFGTLFRVTTYGESHCKSVGCIVDGVPPGLPLEDVDIQAQLSRRRPGQSNLTTPRNEADAVQLQSGIENVTLGTPIGLLVQNKDQRPHDYDLYPRPSHADWTYLGKYGIKASSGGGRSSARETIGRVAAGAIAEKYLKLSHGVEIIAFVSSVGIMSTVTREEIDDSIGGTVTCVIRNCPIGLGEPVFDKLEAKLGHAMLSIPATKSFEIGSG--FRGGSAHNDPFTTTNWSGGVQGGISNGEDIYFKIGFKSPATISQAQQTAKYNGGVLEARGRHDPCVVPRAVPIVEAMASIVIMDQLLIQNSRTAA Zygro1 MSTFGHIFRVTTYGESHCRSVGCIVDGVPPGMSLTDKDIQPQLSRRRPGQSKLSTPRNEKDKVEIQAGIENKTLGTPIAMLIRNEDQRPHDYDNYPRPSHADYTYMEKYGLKASSGGGRASARETIGRVAAGAIAEKFLSQVSNVEIVGFVSQIGLLNTITREKVDDSIGGVVTCVIRNLPAGIGEPCFDKVEALLAHAMLSIPASKGFEIGSG--FSGGSQHNDLFTKTNNSGGVQGGITNGENVYFSVAFKSVATIAQEQETATYDGGVLAAKGRHDPAVTPRAIPIVESMAALVLADSLLIQKSRDFA [Cluster2654.fasta_al_trimmed; alignment length = 112] Allma1 LRLLVPAGKATPTPPVGPALGQRGVKAMDFCRQFNERTAGTPVRVRMTV-KPDRTFTFTTLEPTTSWMLKQAAG-VEGQVSLKAVFEIA-SLEELCRMIAGSARSIGLEI-V Ashgo11 VKLIVGAGQAAPSPPVGPALGSKGIKAMDFCKEFNARTAGVPIPVLITI-KPDRSFTFEMKSPPTGYLLLRALN-QEGELSLKHIYEIALDMENIVKSVVGVAKSMGIAV-V Aspfu1 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGVPIPARVTV-RPDRSFTFDIRTPTTTYLLLQAAN-VEGKVSLKHVYEIALSLQGLCKSIMAQAKSIGIQV-V Aurde31 VRLIVPAGKASPSPPIGPALGARGVKSMDFCKEFNARTAGVPTPTLITI-QPDRTFTFETKTPPVTYFLKKITG-LEGTISMKHVYEIALPLESIARTVVGSARSLGIRV-I Batde5 IRMIVGAGKAAPTPPVGPALGQKGVKAIDFCKLFNDQTSGIPITTIVTV-NSDRSFSFFNKSPPATWLIKQAAG-LEGQISLKHIYEIAVSLEAVCRSIIATSQGMGVTV-I Botbo1 VRLLVPAGKAAPTPPVGPALGARGVKSMDFCKEFNARTAGVPIPTVITI-QPDRTFTFVTKTPPTAYFLKQAAG-VEGTVTLKHIYEIALRLESIASTVVGTARTLGIKV-V Botci1 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGTPIPARVTV-RPDRSFHFELRTPSTSWLLLSAAG-VEGTVSLKHIYEIALSLEGLCKSVIAQAKTIGVKV-V Caeel LRTNIKAQMASAAPPLGPQLGQRGLNVANFCKEFNKETGGVPLPTRITV-KPDRTYDLEICTPTTTWLLKQAAG-IGGKLTVKHLYEIAVPLEQICRMLIKTCRTLGIDVQY Canalb1 VKLVVEAGKAAPAPPVGPALGSKGVKAIDFCKEFNARTAGVPIPVIIQV-KPDRTFTFEMKSPPTSWLLMKAAG-VEGEVSLKHIWEIAVDLKAIVGSVISTAKVVGIKV-V Cangl VKLIVGAGQAAPAPPVGPALGSKGIKAIDFCKEFNARTAGVPIPVLITI-RPDRSFTFEMKSPPTGYLLLKALG-AEGELSLKHVYEIALDMPGIVKSIIAVAKSMGIKV-V Capow LKLLIPAGKAAPAPPLGPALGQKGVAIGQFVKDFNDQTKGTELPVRLAV-KGDRSYSYTVGQPTTAYFVLRAAG-LAGTISLRHVYEIALNMQTMAQCVIGTARALGVRV-I Catan2 LRLVVAAGKATPTPPVGPALGQRGIRGMEFCKLFNDRTAGTPIPVRMLI-KPDRTYTFTTHTPQTSWLLKQAAG-IEGQVSVKAIYEIA-SLEELSRMIAGSTRSMGIKV-V Cioin IRTTMKAGGASTGPPIGPTIGQRGLPIVKFVEDFNNLTKGTPIPTRIHV--DGKKFTIQLLEPESSYLIMQAAG-ISGKITHKHIYEIAMPLKEMCELLAEQAYRLGVDV-V CocheC53 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGTPIPARITV-RPDRSFHFQLRTPPTATLLLSAAG-VLGTVSLKHVYEIALSLEGIARSIVGQAGSLGVVV-V Coere1 LKLIVPAGKATPSPPVGPALGQRGVKSMDFCKQFNDRTKSTPTPVAISI-NPDRTFTFTVKSPPTSWLLKRAAG-VAGTVSLKHIYAIAIGLEKICKSVIATAASAGIGV-V Conco1 LKILVGAAKASPSPPVGPALGQKGVKSMDFCKQFNDRTKGVPVPTLITI-NPDRTFSFVTKTPPTSFLLKRAAG-VEGTVSLKHIYEIALDLKQLCSSVIGSARSCGIKV-V Conpu1 VRLIVPAGKATPSPPVGPALGARGIKSMDFCKEFNARTAGVPVPAKISV-EADRTFTFVTRTPPTAYFLKKTAG-IEATISLKHVYEIALKLEAIARTVVGSARSLGIQV-V Copci VRLLIPAGKAAPTPPVGPALGARGVKSMDFCKEFNARTAGVPIPTLITV-QPDRTFSFVTKTPPVSYFLKQTTG-IEATISLKHVYEIALQLEAIARMIVGSARSLGIQV-V Croqu1 VRLIIEAGKASPSPPVGPALGARGVKAMDFCKLFNAQTASTPMRVKLHI-APDRTFTFQVSSPPTSHFFFKTLG-IEGELSLKHVYEIAIPLESVARSVVAQATNMGIKV-V CryneH991 VKIIVPAGKAAPTPPVGPALGARGVKAMDFCKEFNAKTASLPIPTMITI-NPDRTFSFATRTPPVSYLLKKTTG-IDGQVSLKHVYEIAVGLERVARGVVGTARSLGLEV-V Crypa2 VKLIVGAGQASPSPPVGPALGSKGIKSMDFCKEFNARTAGTPLPVRVTV-RPDRSFHFDVRTPQTSWLLLNAAE-APGTISLKHVYEIALSLEGLCKAIIYQARSIGINV-V Debha1 VKLIVGAGQAAPAPPVGPALGSKGVKAIDFCKEFNARTGGIPIPCLLTI-KPDRSFTFEMKSPPTSWLLLKAAQ-AKGEVSLKHVYEIAVDLQAICGAVILTAEAVGVKI-V Dekbr2 IKLIIGAGKAAPTPPVGPALGSKGVKAIDFCKEFNARTADVPIPVNIIV-HPDRTFNFSIKSPTTSWLLLQAVE-KEGELSLKHIYEIAMPLKDVCKGVIGTAKSLGIKV-V Dicdi LKLIIGAGTASMTPPLGPNLGQYGINSIEFFNDFNTETKGLALRVILWI-NVMKAFYFELQMPKISNLLKEYYK-VEKERLLKDCFKIAKYLRITVLEILGTCRSCKIYV-- Dmel LKTNIPAGMAAAGPPLGPMLGQRAINIAAFCKDFNAKTAGVPLPCRISV-NSDRSYDLAIHHPPATFFLKQAAG-IQGMITLKHLYEIALTMQQMCEMLISIARTCGIKV-V Enthi ---------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------- Fomme1 ---------------------------------------------------------------------------------------------------------------- Fusgr1 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGTPTPCRVTV-RPDRSFTFDVRTPQTSWLLLNAVE-APGTITLKHVYEIALSLEGLCRAVIFQAKSIGIDV-V Galma1 VRLLIPAGKAAPTPPVGPALGARGVKSMDFCKEFNARTAGVPIPTLITV-QPDRTFTFITKTPPATYFLKQAAG-IEGTISLKHVYEIALPLESIARMIVGSARSLGVQV-V Ganpr1 FKLLVPAAKAAPTPPVGPALGQRGVKSIDFCKQFNDATKGTPIPTRITV-KPDRSFSFITKAPQTAWLLMRAAG-IEASVSVKHIYEIALELEKVAKCIAAQTRSLGIKV-V Gloin1 --MLVPAGNARPTPPIGPILGQRGLKAIDFCKQFNEFTKDTPIPTILTM-QPDRKFTFSCNMPPTTWLLKRAAK-IDGKVSLKHIYEIAFDLRSICKSIVATCGSIGIEV-V Hisca1 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGTPIPALVTI-RPDRSFTFDLRTPTTSWLLLKAAG-VEGKVSLKHVYEIAISMQSLCKSVIAQAKTVGIEV-V Klula1 VKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFNARTAGTPIPVLINI-KPDRTFSFEMKSPPTGYLLLKALS-LEGELSLKHIYEIALELEGIVKSIIGVAKSMGIKV-V Lacbi2 VRLLIPAGKAAPTPPVGPALGARGVKSMDFCKEFNARTAGVPTPTLIRV-QPDRTFTFVTKTPPVSYFLKKTTG-IEGTITLKHVYEIALPLESIARMIVGSARSLGIQV-V Lenti61 IRLLIPAGKAAPSPPVGPALGARGVKSMDFCKEFNARTGGVPIPTLITV-QPDRSFSFVTKTPPTAYFLKKAAG-IEGTVSLKHVYEIALRLEAIASTIIGTARTIGIQV-V Malgl1 VKLLVPAGSASAQPPVGPALGAKGVKAIDFAKEFNARTVGLLTPTVVTI-QPDRTFSFRTLTPPTSLLLKRAAN-ITGTISIKHVYEIAITEKEMCKVVAGSARSLGIKI-V Mellp23 ---------------------------------------------------------------------------------------------------------------- Mnele ---------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------- Morel2 LRLVVPAGKATPSPPIGPALGQRGVKSMDFCKQFNDRTKGTPLPVIITV-KGDRTFTFVTKSPPTSFFLKRAAG-IEGKVNLKQVYEIALSLKGICAGVIGSAKSMGIEV-V Mucci2 VKLLVGAGKASPSPPVGPALGARGVKSMDFCKQFNDKTKDTPLPTVITI-KPDRTFTFVVKSPPTTYFLKRAAG-ITGSVSLKHIYEIALSLESISSSIIGVAKSVGIQV-V Mydma FKMYITAGKAAPSPPLGPALGQRGINIMQFIKEFNEKTKGIPIPTVINF-K-DGKFDIFVKNPPATYFLKAAAG-IEGSVSLRQIYEIATPLIGICKTIIHSAHSIGIAI-V Neucr2 VKLIVGAGQASPSPPVGPALGSKGIKSMDFCKEFNARTAGTPMPVRVTV-RPDRSFHFDVRTPHTSWLLLNAAE-APGTVSLKHVYEIALPLEGLCRAVIYQARSIGINV-I Orpsp11 ---------------------------------------------------------------------------------------------------------------- Pench1 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGVPIPARVTV-RPDRSFSFELRTPTTTYLLLNAAN-VEGKVSLKHVYEIALSLEGLCKSVLSQAKSIGIQV-V Phybl2 IRLLVSAGKASPSPPVGPALGARGVKSMDFCKQFNDKTKETPMPTVITI-KPDRTFTFVVKTPPTTFLLKRAAG-IAGSVTLKHVYEIALSLESICGSIIGVAKSVGIEV-V Picst3 IKLIVGAGKAAPAPPVGPALGSKGVKAIDFCKEFNARTAGIPIPCVLTV-KPDRSFTFEMKSPPTSWLLMEAAG-ISGEVSLKHIYEIAVDLQAIVGAVLSTAEVIGVSV-V Plicr1 VRLLIPAGKAAPTPPVGPVLGARGVKAMDFCKQFNERTGGVPTPTVITV-QPDRSFSFLTKTPPTVYFVKKAAG-IEGTISVKHVYEIALKLESIARTIVGTARTLGVEV-V Polpo ---------------------------------------------------------------------------------------------------------------- Pucgr2 VRLIVEAGKASPSPPVGPALGSRGIKAMDFCKLFNAQTSTIPIRVNMTINAKDKSYKFKLNSPPTTYFIKKHL----SELSLKFIYHLAIPLESLTRSIAAQVKNMGIKL-V Punst1 ---------------------------------------------------------------------------------------------------------------- Rhior3 VKLLIGAGKASPSPPVGPALGARGVKSMDFCKQFNDKTKDTPVPTVITI-KPDRTFTFAIKSPPTTYLLKKAAG-ITGKVSLKHVYEIALSLESISSSIIGVAKSVGIQV-V Rhoto1 VRLIVPAGKATAAPPVGPALGARGVKSIDFVKDFNARTAGTPTPVNITI-QADRSFTFTIHTPPTMWLVKQAAG-IEATLSAKHIYEIALPLQSIARAVAGSCRSAGVAI-V Rozal11 VRFRVPAGQASVGPPLGPVLGARGIKAMDFCKIFNEKTKGIPMRIDMKI-YKDRSYRYEIKSPDLSWFFKRCTG---GVITMRHIYEIAYSLQAICKNMLSRARAYKLKV-I Sacce1 VKLIVGAGQAAPSPPVGPALGSKGIKAIDFCKEFNARSAGVPVPVLITI-KPDRTFTFEMKSPPTGYLLLKALK-MDGELSLKHVYEIALEMEGIVKSIVGVAKSMGIKV-V Salro FSMYIPAAAAAPAPPLGPALGQRGINIMEFCKQFNDRTKGIPVPTQVEV-KNDRSFQFKTGMPPNSYFLKKAAG-ITGTVTLKQIYEIATPLEGVCRCIIGSARSMGIRV-V Schco3 IRLVVGAGKAAPTPPVGPALGAKGVKSMDFCKEFNARTAGVPVPTVVNV-NPDRTFTFTTNTPHVSYFIKKTTG-IDATMSLKHVYEIALSLESIARMVVGSARSCGVQV-V Schpo1 IKLIVPAGKATPTPPIGPALGARGLKSIDFCKEFNARTANTPVPCKITV-TPQRTFTFTIHTPPTSWLISKTLD-LEGQLSLKHIYEIAIELLSLCKSVIGTAKSMGVKV-V Sorma VRLIVGAGQASPSPPVGPALGSKGIKSMDFCKEFNARTAGTPMPVRVTV-RPDRTFHFDVRTPHTSWLLLNAAE-APGTVSLKHVYEIALPLEGLCRAVIYQAKSIGVNV-I Sphar --------KAAPAPPLGPALGQRGINIMQFCKDFNDKTAGIPVPVIIDV-KADRTFTYKMKQPPVSYFIKAAAG-VEGTITLKHVYEIALSMQALCKQIISTSETMGIEV-I Spipu1 LRLLVPAGKAAPSPPVGPALGQRGVKSMDFCKAFNDRTKGIPIPTSITI-EPNRTFTFITKNPPTTWLLLQAAG-VEGEVSLKHIYEIATGLREVASRVVGTAKGIGLKV-V Sporo1 VRLVVPAGKATAAPPVGPALGARGVKSIDFVKDFNARTAGTPTPVLITI-QPDRTFTFITKSPPTSYLIKQAAG-IEGTLSLKHVYEIAVELESIARSVIGSCKSAGVAV-V Stehi1 VRILIAAGKAAPTPPVGPALGARGVKSMDFCKEFNARTAGIPTPTLITI-QPDRTFSFVTKTPPVSYFLKQAAG-VEGTVSLKHVYEIALPLEAIASTVVGSARTLGLQV-V Tapde11 VKLIVPAGGATPSPPIGPALGARGVKSIDFCKEFNARTSGVPLPVLITI-RPNRTFAFDIKMPSTAWLLMKAAG-ISGKISLKHVFEVALPLESICKSVVGTAKTMGIQV-V Thetr LKLRIPAGGASAAPPTGPALGQAGVNIMEFCKDFNARSGDTPVPVVVKV-FEDRTFEFTTGPPPTSFFLKRAAG-IDGQVSLKQVYEIAQSLEGLCRSIIGSARSMGIEV-I Treme1 VKLVIPAGKATPSPPVGPALGARGVKAMDFCKEFNAQTSSLPTPTQIRI-NPDRTFTFSFRSPPVTDLLKKAAG-IDGQVSLKHVYEIALGEERVVRGILGSARSLGLEV-V Trire2 VKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAGTPMPCRVTV-RPDRSFTFDVRTPQTSWLLLNAVG-APGTISLKHIYEIALSLEGLCRSIIFQCKSIGINV-V Umbra1 VRLLVAAGKASPSPPVGPALGARGVKSMDFCKQFNDKTKETPIPTVITI-KPDRTFTFITKSPPTPFLLKRAAG-IEGKVSLKHVYEIALSLQSICGSIIGVAKSIGIQV-V Ustma22 VKLLVPAGKASAQPPVGPALGAKGVKAMDFAKEFNAKTAGIPTPAIVKI-NPDRTFSFEIKTPPTSLLLKRAAG-IEGTITMKHIYEIAVGEEQMCKVIAGSARSMGLRI-V Walse1 LRCLIPAQKAAPTPPVGPLLGARGVKSMDFCKEFNAKTGGVPTPTQITI-NPDRTFSFTIRSPPTTHLLKKVAGDIEATISVKHIYEVAKGLENVARSVISTAKNMGIEV-V Zygro1 VKLIVGAGQAAPSPPVGPALGSKGIKAMDFCKEFNARTSGVPVPVLITI-KPDRSFAFEMKSPPTVYLLLKALG-VEGELSLKHIYEIALEMESIVKSVVGVAKSMGIKV-V [Cluster2656.fasta_al_trimmed; alignment length = 70] Allma1 LFSAACHVAYFPFIALRDPLFASCCLLALANHCSWFTSFMIQLAAFYGVCLWLVPLLLFLSLAVGDHILP Ashgo11 CFSIASHVVYFPFISLSSPTFVASCVLVALNHYLWLRHFLAEVTSFFALCVWFIPFALFVSLSAGDNVLP Aspfu1 ---------------------------------------------------------------------- Aurde31 GFSITCHVVYWPFISLKSPSFIASCVLVVADHFLWFHHFFMEVAAFFGVCVWLVPLFLFLSLSANDNALP Batde5 VFSLVCHAWYFPAIEATSVKFIISCLLAVADHFVWFFYFISEIGSFFAILVWMVPFLFFISLSANDYTLP Botbo1 LFSAFCHLVYWPFISLTSPAFIGSCVLVISDHFLWFYYFFMEIATFFAICVWFVPLFLFLSLSAGENALP Botci1 VMSILSHLVYFPVVHLSNPLFLISCALVIVNHYLWFRHFFTQIASYFGLCVWLTPFALFVSLSASDNVLP Caeel ---------------------------------------------------------------------- Canalb1 LFSIFSYYVYFPYVELSSPVFLLSCVLVISNHFLWFHHFFVEICSFFGLLVWLVPFALFVSLSAHDNLLP Cangl LLSIVSHLVYFPVISLTSVSFIASCVLVVLNHFLWFRYFFAEVASFFCFCVWFVPFSLFVSLSAGDYLLA Capow IVGLAANGIYYPYFTVYSFEFIGSCVMVFVHHFASFSVFFLHIVAYFTLCVWLIPFVFFISLSANENTLP Catan2 ---------------------------------------------------------------------- Cioin AVGLFTNLVEFPFIELTSPNFIGTVLLVFVNHYLAFKYFFAEVLSYFTLCLWLIPFTFFISLSAGDNVLP CocheC53 LLSVVSHGIYFPVVKLTDPLFLLSCALVIVNHYLWFRHFFTEIAAYFGLCVWLVPFALFVSLSAGENVLP Coere1 VASAAVNHVYFPLVDLGSASFVGSCVLAVGNHFLFFFYFFDQVCAFMFFGVWLVPLALFVSLTPVDSSLP Conco1 ----------IPTLEVETFEIIATCATTLINHFLWFYEIVWEMLCFFIILIWLVPIGLLLSCTTPLTSLP Conpu1 AFSVFCHAVYWPLISLSSLSFIASCLLAIADHFIWFFYFFSEIATFFGICIWLVPLFLFLSLSANDNALP Copci ---------------------------------------------------------------------- Croqu1 LLGVTCHLVYWPFISLTSPSFIASCLLVIVDHFAWFFYFFLDITTFFAFCIWLVPFFLFLSLSANDNVLP CryneH991 LFSITCHLVYWPFISLTSPRFILSCILVVGDHFVWFFHFFGDVAAFFAICVWFVPLYLFLSLSANDNALP Crypa2 MLGIASHIVYFPFVTLTDPLFITSCVLVLFNHVVWYRHFFTEVASYFGICVWLVPFALFVSLSASDNVLP Debha1 VFSIFSYYVYFPYVQLTSPIFLASCILVVLNHFLWFDHFFVEVCSFFGLCVWLVPFALFVSLSAHDNLLP Dekbr2 LFTLFSYYVYFPIVNIKGPIFIATCILAILNHYFWFRYFFAEIASFFGICVWFVPFALFISLSSADSSLP Dicdi LFSFIGHCCYFPFVTLTGYKFILSVLSFIISHISWFIYFFGEIIAIFTFCVWLIPLIFFISLAANDNSLP Dmel ICGLVAQGFHFPFVRLLSLPLLGSLAMLVVNHFLAFQHFFTQVLAYFTICMWIVPFALFVSLSANDSVLP Enthi IVNLISQAIYVPYISYKSPIFFGGCVAAVLSHLVFAIHFFWRLLLINIYTLWTVPLLLLASVVIAPEALV Falba LFSLGCLVAYYPSVKLTSPKFLVSVALSLANFLSWLELFASHVVSFYSVCVWLVPLSYLLSISVDEYLLP Fomme1 LFSIGCHVVYWPYISLSSIAFLASCALAIVNHFMWFFYFFPDIATFFALCVWLVPLFLFLSLSANDNALP Fusgr1 VLTIVSHVVYFPFVKLTDPLFLASCVLVLVNHYVWFRHFFAQIASYFGLCVWLVPFALFVSLSAGDNVLP Galma1 IFSLTCHVVYWPLISLTSLSFLASCALVIADHFIWFFYFFTEIASFFAICIWYTPLFLFLSLSANDNALP Ganpr1 LFSLACHIVYFPIVRLTSWLFLLSCALAVINHFMWFSFFFPQVASFFAIYVWLVPFEFFISLSANENVLP Gloin1 ---------------------------------------------------------------------- Hisca1 TLSIISHFIYFPVVKLTDPIFITSCLLVGLNHWLWFRYFFTEVASYFGLCVWLVPFALFVSLSAGENVLP Klula1 AFSIFTYVVYFPYISLTNPTLMLSCVLVLINHYLWFKYFFAEVASFFGICVWFIPFALFVSLSAGENVLP Lacbi2 IFSIACHVVYWPLISLTSPSFLASCVLVIADHFIWFFHFFIEIASFFGLCVWLAPLFLFLSLSANDNALP Lenti61 LFSVFCHLVYWPFISLSSTSFLGSCVLVVVDHFLWFFYFFGDIATFFGICVWLAPLFLFLSLSANDNALP Malgl1 ---------------------------------------------------------------------- Mellp23 ILGIFSHLIYWPMISLNSISFLSSCCLVILDHFAWFFYFFLDVTTFFAICVWMVPFYLFLSLSANDNVLP Mnele ---------------------------------------------------------------------- Monbr ---------------------------------------------------------------------- Morel2 LFSLACHAVYFPYISLVSIPFLSSVVLVLVDHFMWFKYFFMSIASFFGICVWLVPFTYFISLSANDNALP Mucci2 AFSVFCHCIYFPFISLTSIPFLSSCVLVFVDHFLWFNYFFMDIAAFFGLCVWLVPFAYFISLSANDNALP Mydma GLGFFTSIDHFPNISLLSPSFIIAGVMVFVNHYYAFQYFFSEVLAYFTLCQWMVPFAFFVSLSVNESTLP Neucr2 LLSVGSHVVYFPYVKLTDPLFVLSCGLVLVNHYLWFKHFFTEIASYFGICVWLVPFALFVSLSASDNVLP Orpsp11 IFSIFCHLTYFPNIQISSPSFILSCVFVLVDHFVWFNYFFNEIVCFFAICVWAVPFEFFISLSANDNTLP Pench1 LLSIASHMVYFPIVKLSDPLFILSCLLVGLNHWLWFRHFFSEVASYFGLCVWLVPFALFVSLSAGENVLP Phybl2 AFSLFCHGVYFPFINLTSLPFLSSCVLVFVDHFVWFRYFFMDIAAFFGICVWLIPFTYFISLSANDNSLP Picst3 LFSVFSYWVYFPYVELSSPVFLVSCVLVVANHFLWFNHFFVEVCSFFGLLVWFVPFSLFVSLSAHDNLLP Plicr1 AFSIGCHIVYWPLISLSSWSFIASCLLVVSDHFAWFFHFFAEIATFFGLCVWLAPLFLFLSLSANDNALP Polpo LLSLISHGSYFPFVTLTSVKFIISIITMIVSHCWWFMFFFSEIISVFVFFVWLVPFIFFVSLSANDSALP Pucgr2 ---------------------------------------------------------------------- Punst1 LFSVACHVVYWPLISLSSPSFLASCVLVVADHFLWFFYFFADIATFFGICVWLAPLFLFLSLSANDNALP Rhior3 TYVPLCHFVYFPFINLTSLPFISSCILVFADHFLWFQYFFMDIAAFFGICVWLVPFAYFISLSANDNALP Rhoto1 AVGVVAHLIYWPVISVKSLTFVLSCLIVLLSHYLSFRHFFLEVATYFGVCVWLVPFYLFLSLSANDNVLP Rozal11 ---------------------------------------------------------------------- Sacce1 LFSIACYIVYFPFISLTSPTFLLSCVCVVLNHYFWFKYFFAEVASFFGICVWFIPFALFVSLSAGDYVLP Salro ---------------------------------------------------------------------- Schco3 IFSIVCHIVYWPLISLASPSFVLSCILVIADHFIWFFYFFTEVATFFGLCVWLAPLFLFLSLSANDNALP Schpo1 AFSIFSHYIYFPFFSFKRMRFLLACFLIVANHILWVRFFFSQVASFMGVCVWSVPIGIFVSFTAADNTLP Sorma LLSVGSHVVYFPYVKLTDPLFVLSCVLVLVNHYLWFKHFFTEIASYFGICVWLVPFALFVSLSASDNVLP Sphar LPGLVAHGFYFPVCNFASVGFVSSTVMFCVHQYCVFSYFFADVLAYFTVCVWLVPFIFFVSLTSNDGNLP Spipu1 LFSLSCHLWYFPTIELSSVAFVLSCVLVIVDHFVWFFYFFMEIATFFGLIVWLIPFMYFISLSANEYTLP Sporo1 AVGIGAHVIYWPTISLTSISFVLSCISVLLSHYLAFRHFFLEVATFFAVCVWLVPFYLFLSLSANDNVLP Stehi1 LFSIACHIVYWPIISLSSPSFLGSCILAICDHFLWFFYFFGDMATFFGVCVWLAPLFLFLSLSANDNALP Tapde11 ---------------------------------------------------------------------- Thetr MWGLAAHAVYFPFIPLVSAKTVASVVGLGLDHWMWFRYFFSFVISYFGLCIWLVPFLFFISSSANDTALP Treme1 IFSIFCHIVYWPYISLTSIKFIASCCLVVADHFIWFFHFFMDVAAFFAVCVWFVPLFLFLSLSANDNALP Trire2 VLGIFSHVVYFPFVQLTDPLFLLSCVLVLCDHYVWFRHFFTMIASYFGLCVWLVPFALFVSLSAGDNVLP Umbra1 LFSLACHGVYFPFISLTSPPFLASCVLVLIDHFVWFQYFFMDIAAFFGVCVWLIPFAYFISLSANDNALP Ustma22 LPALIAASLHWPYSAASSSLGLCTSVLLPLTSHIWLVRYNLQVCAVLVVCVWSIPVYRLLGRVAA----- Walse1 ---------------------------------------------------------------------- Zygro1 LFAIASYFIYFPFISLTDPIFLLSAACVLLNHYFWFQFFFAEVASFFGICVWFVPFALFVSLSAGDYVLP [Cluster2657.fasta_al_trimmed; alignment length = 200] Allma1 MRMKFKVSPKTLAKLVAPLDKLCTLRFSRHRFADATQVWSHAPADLLF--E--EMSEIALSVPTALLHRAVKSMATAAVTVKLARNPVLAMTMVHHDVPIRVLSAIDELREPPWSDVYVALP-PLATLRAMIDRIKAMGLTLASRLRIRATPNVQFETVIGR-LEHAVATADFSRVAHP-TQVVLIHHQVCAVVYAHLDA Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MRFRSQLNIVTFT---------------NGIVDQGTQVWAQLPVDAIF--DEPTYGVINLEVPIGALHRALRSATGASAQLRLTKKPLLALTIITQEIPVKVLSAVEGLHEPRDPDVHIILP-SLAHLKSISERFSKLALELSANLRLAITDALRISSVWSD-LVNPIDAKDWSRVLSP-KVVACFIHETALILYVYLPQ Aurde31 MRFRATVNVQTFYRVVQSLEKLCMITMNESTMDNGVQLWSSIKVPHIF--T--DYNEITFEMGTEPLLAALKSALGSEVVLKLTKKATWSFEVVVHDVRTTVMADVARIHEPPEPDVHVILP-PLAKLRTPMEHMQRISVLIKANLRFMVTDKCCLESEWTG-CKHPLPMKALFKFVST-TTIAGLCHGHCVIMYVYIGE Batde5 -----------------------IFHLSPDRLNTGVQVWAQLGTETLF--E--DYNHIWLEVKGDHLLRALKSGQKSQMIMRLSKKPVLSFTILVQDVPVRVIDKTHEFREPPDFDVHILMP-PILSVRNIAERMKAVGLVISANLTMGVNDIVKIQTFFKD-LINPVDIRDFIKFLHP-SKILCINEQSCLIFYVVMGD Botbo1 MRFRANIHVSTFSHIIQSVEKLCIIKLSETALEGGVQVWSRIKVDSLF--S--EYNEINLELSTESLLQALKSANESEVMFKLAKKPVLTFEIITHDVRILVKSDMEKIKEPPEPDVHIVLP-PLSKMRIIAEHFSQVSIGVSANLILSITDDVKVETQWSG-CEHPVTSRSLLKFIST-TTIACICSDYCLIMYVYIGE Botci1 MRFKTSVNIQTFSKLTASLSSLAWVRLDDNGVETGTQVWASLAIDSIF--E--DYNTINIELPLPPLHRALKSAINASASIRLTKRPVLSLTVVTQDIPIRILDSVEGIHEPRDPDAHIMLP-SLIQLKAISERFTKLALELSANLRLSITDALNISSVWTG-LNNPIDGRDWGRVLGG-RVIACFVNDHALILYVYLDN Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow MRFKASINVIKLQRIVATLAKICVIRFTPTQLDRAARVWSDITQTSIF--K--TYNEILVDISLDLLQRALKTANNATVTMRMIRKPFLVLDVLCQQIPMLILSLIDDYQEPPRPEVSIYMP-SLKLLRNVVERMKTISLDIAANFWLRVSDMLEIRASFPN-LQNPVAIKHFAQFVGA-SNVICIVEDKAVILFLIDDG Catan2 MRLKARINPRPLHNLTSSLSPLLVLKFTPTQLESSTQVWCTLPAASVL--D--DYNEIYLQCHLPTLARAVKSMLHANATIKLTRSALLAILVISHNVPVIPLTQAAELREPGVPAVYITMPKPLTMVKVVAERMKALGVSVKANVKVSVGAHAEVETTWGG-----VGARDFVKFANP-AHVICLIPGMCAVFYVYMYS Cioin MRFRAKVCIHHFTNVVNTISKLCSIRLTKEKMNGGVSMWCELKQANFF--D--EYNEIYLEIVAENLCRAIKSANNASLKIKLTKKPCLTVEIVTHDIPVSVISLWGEYQEPPDFHVSLCLP-PLKTVKHIVERLKNLSLTLSGNFALKVTELVSATTRFSD-LEIPIDVKKLLQFINP-YKVICIVDQSAVHFFLVHDD CocheC53 MRFKASINITTFTKLTASLNSLAWVKLSEEQVEQGTQVWAVLSIDSIF--E--TINVINLEVPLASLNRALKSAVNASAQIRLTKKPMLALTIVTQEIPVRVLDTVAHLHEPREPDVHIILP-PLMQLKSISDRFTKLALEIAANLKMSISDAMNISSIWTD-LNNPIDGRDWGKVLGG-RVIACFCHEHALILYVYLPN Coere1 MRFRTLVNSNLLLRVVQSIDKLAILKLTTEKLDSGLQLWSDIAVNALF--S--DYDEIYLEFTIDNLQRALKSAQGAHTTLKLTKKPVLSLVILNQDVPVRVLLQMDAIREPPDSQVHIMMP-PLNSVRSIAERMKGMGVAVSANATLRVNDLVEITTFFRG-LENLVDMKNFLRFVAP-KNIVCIIEHHSLVFYVYIGS Conco1 MKFSATFSTQLIHKICQIFEKVCLLHLTKDYLGQEPQVWLQVKMDQVF--A--DFDKIYLELDASHWVRSLKESILGNSTLKLTKSVVLKMVIVTHDIPVRVLSQFNNIAQPEEFTMRVQMP-TLISLRHVIERLKTLGITINANFQIKMSEKCDINTTYP--ISQSVDIKHFSQLLNP-WAVILYSHNNAILAKILLND Conpu1 MRFRANINVPIFYRTIQAVEKLCIIKFTETEMEGGIQVWSVVKVDSIF--A--SYNQITMILATDALLQALRSSSTSEVVMKLAKKAVLAFEMVAHDVRVDVMSDVDRLREPPEPDVHILLP-NLQKLRTIVERIRPLSIAIRANLQVSITDTVKLETQWTG-CANPVSIRSFLKFVST-TTIACVCQNHCAILYVYIGE Copci MRFRTTVNVSTFFRLIQTIEKLFIIKFTETTMEGGIQVWSQIKVPSLF--T--NYNEITMVLSSEALAGALRSAAANEVVMKLVKKGMLSFDIVTHDVRVDVMTEVAKLNEPPEPDMTVLLP-PLHKIRTIVERLRPMSLAVRGNLQLSITEGVKVDTEWRG-CTNPISIRSFLKFVSS-TTIACVCHHHCLILYVYIGE Croqu1 MRFRAQVNLAAFTKLVDSVAKLAVFMFTPIELDDGVRFFGTVNVKDLFE-H--HYNQISLELTTQALASVLRASSGSEMVIRLGKSPVLSFVVLEQHVAVRVLADAEMLREPPIPNVQITLP-KLTDVCKVAERLKSLSIHVSANLKLGISEHVNVETEWRGLALGPVKSRGLLKFIAE-LSLACVCEAHSLIMFIYIG- CryneH991 MRFRTGINVGLLHKIIRSLAALCVIKLSEEQVATGVQVWSQVKVSTLF--E--DYNEIWVEVNLDSLVKVLRSADNSEVTLKLNKKPIWAFDIITHEINVKILRRQEDLKEPPRPDIHVVLP-NLQELRNIVSRLAPVAVDVSANMELAVSSKVNLTTTWKE-LAIPVTIKALLKFISG-EAIMCICEGYCVIAYVYIGP Crypa2 MRFKTELNIRTFNKLIAALNSLAWVRLDDETAETGSQVWASLSMDFIF--N--DYNTINLELPLNPLQRALKSAINSHATLRLTKKPVLSMTIITQDIPVRVLDTVETIMQPREPEVHIQLP-PLMQLKAISDRFTKLALELSANLRLRITEALNIESVWRN-LDNPVDGKDWSRVLEG-RVIACFADDHALILYAYVPQ Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi MKFKAKIKASILLKTVQNIMKICICHITPDKLNDGMQVFCEIQRSLIF--E--NFNEIQFQLDLESLRRVLQSATS-DIFTNLTKVPVLHFIIIFQDIPIVLLQQMAQINEPPDPLVHILLP-NLKNLQKVIDKMKNISIMIAMNLSFEVTSSGSISTFYSG-LDHPVDIKKFAKVLKPSEVVLCLYE-RSIIVHVVLTD Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi MRFKAEIKIEAFLNVVRFFAAVGVFAIGKEDFSQLYSIFMS-KLSPLF--SAFEYDHVYLEFSTDDLLRVMLNIKESVCQISLTRSPCLNFK-VTQELIVTI-QGADLYHQPAQMDVSGQLH-SMKQMKQALDKMAELSVVFSASIRLVCSKQSKMEVVFSEQDHQPCQSGQFKKFLEP------LCE------YYYEKD Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 MRFRANIHVQTFQRIIQAIEKLCIVRFTESEMEDGVQ-------DSLF--T--DYNEISLLLSPEALLQALRSAASSDVVMKLAKKPVLSFEIVAHDVLIDVLAEMARLKEPPEPDIHILLP-PLQKLRTVVERMRSMALGIYANLRLTVSDQVRVKTEWSK-CIIPLSIRAFLKFVST-TTIACICEDHCMILYVYIGD Fusgr1 MRFRTELNIRTFAKLVAALGSLAWLRLSDDTADMGSQVWASLAMDFIF--D--GYNTINLELPLQPLQRALKSALNSSASLRLTKKPVLSMTIITQDIPVRVLETVETIMQPREPDVHIQLP-PLLQLKAISDRFTKLALEISANLRLRITETTDICSVWSN-LENPVDGKDWSRVLEG-RVIACFADDHALILYVYVPQ Galma1 -------------------------------ME--VQVWSRIKVDALF--D--NYNEITMALASEALLGALKSASS-EVVMKLAKKALLSFEIVAHDVKIEVLTDVEKMTEPPKADLLILLP-PLQKLRTIVERLHHMSMAIQANLLLTITEGVNIETEWKD-CQNPISTKSFLKFVST-TTIASVCQHHCVILYVYIGD Ganpr1 -------NLPSLTEIAQSANSLCIARITPTKVDSAIQLWAHIEADKVF--E--DFNEIWLELSPELLARSLKSTAHAGTNLRLTKRAVLSFQVITQDLPVRVLAQADVIQEPPDPQVHIMPP-PLSALRPLVDRLKQLSCVISANWRVEAADGVTVEARWEK-LVNPVDSRDLAKFVNP-TKVVCLIENHAVVFYVYIRD Gloin1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 MRFKSQLDVKTFAKFTASLSSLCWVRLEDEAVDQGTQVWAQLPIGIVF--E--SYGVINLEVPISALHRALRSAIGASAQLRLTKKPLLALSIITQEIPVRVLATVEGLHEPRSPDVFIVLP-SLIQLKSISERFTKLALELSANLKLAITDTLRISSVWTG-LLNPIDGKDWGRVLSP-RVVACFLHDTALILYVYLPD Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MRFRATIHVPTFFRIVQAIEKLFLIKFTETNMEGGIQVWSQIKLDSIF--T--NYNEITMVLPSEALLAALKSASA-EVVMRLAKKALLSFEIVAHDVKIEVMADVEKLSEPPEPDVHILLP-PLQKLRTIVERLRPMSLAVRANLQISITEGVKVETEWKD-CVNPVSVRSFLKFVST-TTIACICQHHCMILYVYIGD Lenti61 MRFRANIHVDSFIKIVQSVEKLCTIQFAEHEMEGGIQVWSSIKVDSLF--T--EYNEITISLPTDGLLVALRSAAAPQVIMKLAKNSVLSFEIVVQQLLVDVAADIERLKEPPEPDVHILLP-PLAKLRTVVDRLRPLAITFRANLQLAVTESARVEIGWTG-LTNPVSHKCLLKFVST-TTIACICENHCMILYVYIGN Malgl1 --------------------------------RDGVQVWTTLDVNTVF--T--NYNEITVEVSAESLARVLRSAVGAEVMLRLGKRPLLSWSIVVQELVVRILSELALIVEPPTPDVYIVMP-PLSEMHAMSELMRTLSVSLSANLKLSLDQHVEGSACWFQ-LEHPISMKAMQNVMAK-STVACICAGYCVVFYVYISG Mellp23 MRFRAQVNLSAFTKFVESVAKLAVFKFTPTELDDGVRFFGTVHAEEIEL-N--QFNQILLELTTQALNSVLKASSGSEIVIRLGKNPVLSFVTLEQHIAVRVVNDTEILREPPVPDVQITLP-KLADVCKVAERLKSLAIQVSANLKLGISEHVDVETEWHGLILGP--------------------------------- Mnele MRFKAKLSITQLQSVISAVSRFCCLKLTEDKICGGTTIWCEVTQSSYF--D--EFGAILMSVSPDMLAKSLCNTVGASVKVKLAKKACLSVEIVTHDVPVHLISHWQEYEEPPEFDISFYLP-PLRKLRNVLERIKNLSVTVQGSMTLSVTELVTTKTYFTD-LDIPVDIKKLLTFIGA-SKSICIVHNRALQLFLLQDD Monbr MRFRSTFAVMVFEQTLTCFQRAVGVRFCEDKVRRDANLWAEMPRNELF--S--EFKQIMVELRLELLIKAFSSTKDASVHMRLRKQAYLAVRIIQQDVPIQVFTAIADYPVPPPSQVHIFLP-DPRRLRLILERMKTFSITIQANLLLQSSEMVSISTTYHG-LTNPVDTAKVQAF------------------------ Morel2 MRLKATIRNLLFFKLAQAVEKVLYIKFSKDYVGGGLQCWSRLPAGALF----YGYDEINIELKAEDLLLAMKSATNSSVTMRMTGRPYLTFVVITLDIPILKIEDTHAFDEPDDPDVYIMPP-QLDRLRNMLTSYKGLCVVISANMVFTTAEKAQVETRFSN-LFNPIRVSDLQRVVRP-QNVICLLDNQSILFMVYMRD Mucci2 MRFKAILNPVGLHKLGQTMEKLCIASFATDKLAVGPQAWTDVVATSLF--S--DY-EINFFFKIPDLLHITKDLHEIRIQVGLKRRSIILFRWEQKELPIELVDRLELIKEPRTPETYILLP-PLVSLKPAAEQFKKLSITVAANLKIEVSAYAVCSAHFDN-LSNPIKSEDFVNFLEP-DDVICIASEAQIVFLVYLNL Mydma MKFRAKLCIQQFTKVLSTVSKICTLRLSQDQVNGGTSFWCEMNQVDYF--D--EYNEIYLEINNENVLRAMRSGHTAFIKIKLTKKPCLTFEIVIHDVPVAVIRYWDDFKKPPNYNIKIHTP-NLKIMKSVVERMKNISMVITALLCFKVTDEVTASTYFQN-MLVEVDIQKLLSFLNA-TKTICIVDQKAVHMFVDCND Neucr2 MRFKTELNIRTFSKLVAALNTLAWVRLDDDTVDTGSQVWASLSVDTIF--D--SYNTINLELPLGPLQRALKSALNSHASLRLTKRPMLSMTIITQDIPVRVLDTVETIMQPREPDVHIMFP-PLLQVKAISDRFTKLALELSATLRLRLADTLDITSVWDSCLENPVDGKDWSRVLEASRVIACFTHEHALILYVYVRR Orpsp11 --------------MLQSVEKLSVIKFTKEKI-TELQVWGQVASNLLF--E--EFNEIWIEIRTDQVIRVLKSAQSADVYCKLTKKPSLSFNILVQDIPIRVLYHIKEYKEPPQPHVHILMP-PLVSVRTIIDRMKSMSLTISANFTLKITESVLVETYFKD-LVIPISIIDFEKFINP-SSVICIIENFAVVFYVYVKN Pench1 MRFRTQIDSKTFSKLTASLSSLHSVGINTSRK-QGT----------IF--DDTTYDAINIEVNISVLNRALRSAWGAHAQLRLTKKPLLALTVITQEIPIKILSAVEGLHEPPDTEVHIILP-NLAQLKSISDRFTKLALELSANLRLAITDELRIASVWSD-LVNPIDGKDWSRVLSP-KVVACFVNEMALVLYVYLPH Phybl2 MRLKATVNPVGLHRIVQTLDKFCVMSFSTDSIAGSIRAWVKAQPSAFL--S--NYCEIPLTLRLEFLLPITKIAQNADVKISLKRS-------LVQNISVVAVATMPAIRDPNSPHVFIFLP-SMNSLKPVADRLRQIGMYISANLKLIVNDVAESDYELE------ITTEDFVNFLVP-DNVICITDNEQLAFYLYINN Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 MRFRATINVPTFYRIVQAIEKLCVIKFNETEMEGGIQVWSSIKVPSLF--T--SYNEITLLLSPEALLAALRSASSSEVTMKLAKKAVLNFEVVSHDVRIEVMVDVARLTEPPEPDIHIVLP-PLQKLRTIVERMRPLSLVVRANLVLGITESVTLDTTWTN-CANPISIRSFLKFVST-TTMACICEKHCMILYVYIGD Polpo MRFNAKVTAKRLLKVVQIIMKICILHIAPDATNDTMQVWTEAKTYLFF--E--ETNMIAMQIQLHHLKQVLQSAVNVDTLVRLRKKPFLTFTILTQDIPVVVLQILSGFVEPPTNNLNFFMP-ALKHVQNVVEKMKNISIEVNTNLCFSVTGTGSIKTFYD--ISYPVDIKKFLKTIEANHVVCCVYEGSSLVLHVMQRD Pucgr2 MRFRAHLNVATFTKLIDSVNKLAVFTFTPEEIEDGLRLHGAIKVVDLFG-S--NYNIIPLEFSTQALASAVRQTSSSEIVFRLGRLPYLSLTAVEQRVAVRVVEEAELLPKPPTPDVFLCLP-KISDICKVAERLKSLSITVSASFRLGITEHARVETEWRGL----VKSRAFLRFIGD-VSLASICEGYCLTLFNYIGD Punst1 MRFRATVSLPTFSRIIQSIEKLCIIKFTEPDIEGGVQVWSQIRVSSIF--T--DYNEITMSIATEPLLAVLRGVSSSDIVMKLAKKAVLQFEILAHHVPIEVMSDVAKLKEPPEPDIHLILP-SLTKLRTVIERLRPMALTVSANLQLGVTDTVNIKTAWSK-LVIPVSVRSFQKFVSS-TTIACLCARHCMILYVYIGD Rhior3 -----------------------------------------MQPHSLF--T--NY-EINMSFRVNDLLLITKKAQQADVQIYLKRKPYISWKLMIDELEIEIIDRMAYIREPAMPHTYILLP-NVAVLKPVAERLKSLSLTLSANL------------------------------------------------------ Rhoto1 MRFRAEINPSQFARLISSLSPLATLKLTEETTKSDVQVWSQIANDSIFNTS--TMNEIYLQLSLDHLAKALRSASGAQVTAKLAKRPVLSLVIITQDVAVKVLDDLKELKEPPQPEVIVILP-ALQKLRTVTERLKTISVTISANLRLRAADEAKVETEWRG-LKRPLDTKNLLRFVAT-TTIACFCSNHCAIFYVYVGE Rozal11 --MSSNI--------VQDVSSICILTFTNRKRSTGLKI------------D-CNLDTIHIQVAPNLIVEAVRNVHRGDIYLS----HSICFVGIKQMVPIRIVSSNYLVSEP----VQIYMP-SFQIVKTAIEQLKKINITLSANLEFQTHDLGKVKMAFSN-LTNP------------------FTKDSMITLIVYFEE Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro MRFRARMNVATLTNIVTVFQKATCLRITPSRLD-SERIWIEVLQANLF--E--SFSEVLLQFNLDHFARALRSASNCDLVIKLAKKPYLTFKIIVQDVPVLVRDDIDAIMPPPIPDVNIYMP-DIKLLRNIVDRMKAIAITVRANLELLVSEIVTVKTCFNN-LDNPISARKIAQFLGD-SNNLLSIGSRNVILFLLHDD Schco3 MRFRATVNVSLFFRLIQSIEKLCIIRFTEETMEGGIQVWSQIKVITIF--T--SYNEITMALASDALLATLRSCT--DITVKLAKKAVLSFEIVAHDVRIEVLADVERLGEPPDPDAHILLP-PLQKLRTVVERMRIMSLAIRANLQLAITDDVSVDTVWRN-CTNPVNIRSFIKFVSS-TTMACICQNHCMILYVYIGD Schpo1 MRFKTRINLYTLTRLVQALDKICWLRLMPETVFRMTQVWSVLEVETIF--E--DYNVINLEVPIDNFYKALRSAANADSTVRLSKKPLLSLSTVTHNIPVRVLSYVSVIKEPPEPDCHIFLP-QLNFLRHVVDKYKSLSIIMSANLQLSVIPSARVSTKWKG-LENPLDSKDLVNMVAK-RVIACFCEGHALVLYVYITD Sorma MRFKTELNIRTFSRLVAALNTLAWVRLDDDTVDTGSQVWASFSVDTIF--D--SYNTINLELPLGPLQRALKSALNSHASLRLTKRPMLSMTIITQDIPVRVLDTVETIMQPREPDVHILLP-PLVQLKGISDRFTKLALEISANLRLRLADTLDITSVWDGCLENPVDGKDWSRVLEGSRVIACFTHEHALILYVYVRR Sphar MRFKATIQVQRFTRFITTISRIATLRMAPGKLDGSVRVWAEVEAETIF--D--SFNEILMEIGLENLQRALRSASASDVVFRLTGDPALTLTIVIQNVPVALLELTANYCEPPQPDINICLP-SLKILSTIIDRMKTLDVVLSANLRLQIADAVSVCTSVTE-CEIPIDIKKFSQFMSP-TAVICIVPHRAVILFLLSHE Spipu1 MRLKTKVNAGLLIKMAVSVEKMWIWHFSPDYISTTMQMFGQIKADRMF--E--EYNNIWIELTGEHLVRALKSSQQANVAMRLTKKPVLALSILSQDIPVRPLQEAEDLKQPMDYQVHILLP-PLTDVRTIAERMRPLGITVSANFLLKVTDAVRVETTFSG-LVNPVDIRDFVKFINP-RNVVCLFEGQGLILYVYLGE Sporo1 MRFRAEINTYQLTRLITSLAPLATFKLKADVVRGGVQVWSQIAVNSIFKVE--TLNEIYLEVALDAFARALRSAAGAKAVIRLAKKPVLSIDIITQDVYVKVKQDVEQLKEPPAPDAALLLP-PLQILRTVAERMKTVSITLSANFRMRAADEAKVETEWIN-LKRPLETKNLLKFIAQ-TTIFCLCPGHCGIFYVYVGD Stehi1 MRFRASINVDTFHRIIQTVEKLCIVKFTESEMESGVQVWSQIRVISLF--A--DYNEISLALSTTALSAALRSATSNEVIMKLAKKAVLSFEIVEHDVRIEVLAEVARLSEPPEPDIHILLP-PLLKIRTIVERLRPLAIAVRANLQISATESAKMDVVWEG-CANPVHVRSFLKFVST-TTIACICQHHCMILYVYIGE Tapde11 MKFKSTIDIPTLTKISQSLALLAWIRLTPDRV-LRTQVYVEIDKESMF--T--SYNVINLELNVDSLGRLLRNLADTQVSMKLTKRPMLSFSTVTHDLHVRVLAFIAQVSEPPVPDVIVLLP-ALAHLSQISAPLRSLSLVLRGNFAIGITPAVSTSTLFQN-LTNPVDAKDWCNLVAK-RAIACFCEGHALVLYVYLSE Thetr LELQAQVNQSLFLKLLTAVERTGIVQLTPERVSEGIAVWSGVQTNAVFG-E--TFNTIGMHLSLTDLVRALKTGMTASLVIKLTKRPHLSLVCVTQDVPVEILARLADHAEPAEADVALMLP-SLAHIKNVLDRMRHLSVVI--------TDMVTVSTDYSS-LELPLNIGHLARFIAPDHAIICLLRSSAAVIHAIRDD Treme1 MRFRTTIHISLLRKIVQSLGAICVVRLTPEKVRDGVQVWSQVKVETLF--Q--SYNEIWVEIHLEAFLKVLKSAPE-EINLKLNKRALWAFEIIIQDVKVVVLKRQNELNEPPPPEVHVVLP-KLVELRNIIHRLGHITVTVSGNLELRGGRNADLTITWKE-LQIPVSIRGMLKFVGG-EAIACLCRRHCLIVYVYIGE Trire2 MRFHSDLNIRTFAKLTAAFSSLVWLRLSDETADTGSQIWSTLPMDFLF--E--NCNTINLELSLQPLHRALKSAQNSSASLRLTKKPVLSMTIITQDIPIRVLDTVASTVQPQEPDVHIQLP-PLLQLKSISDRFTRLALEISANLRVRITETADISSAWTD-LDNPVDGKDWSRVLEG-RVIACFCHNHSLVLYVYIPH Umbra1 MRMKCQVNTLGLYKLAQALERMLTLIFSPNSLAGGMQVWVTIPQGTLF--S--SFSEIPLDLRLEDLAQAMRAAQEFNVSLQLIKKAYLEFVMLTFEIPVRRINARATIREPRVPEAAILLP-NLLSLRGDINLLKSQTITLSANFRWRVTELVTMEKQYNQ-LENPIPIEDLVNFLSP-GNVVCIHDERHITLHVAIHF Ustma22 MRFRTQIDVSIFTRVVQSIGKVCILKLTPDKITDGTQIWSQMQVDSIF--Q--DYNHINLEVSPDTLLKALKSAHNASVILRLAKRPLLSFSIVVQDVLIKVLAEMSRIVEPPEPDVHIILP-KLLHLRTVADHMRSLSVTLSANLRLSVEDEVSLDTTWSG-LAHPLETKSLLKFVAT-TTIACICANHCAIFYVYIGD Walse1 ------M-------------------------DTALKSWLQVSVDTLF--T--AYNEVHIEVSMEQLYRAIKSAHETDVLLRLMKKPTLNLSIIEQDVPCRPQIYVDTFDQPPERNVTVQLP-SIPKLKTVLEKLRILDVTIRANLEFSINDQVGVRTTFEK-----VDSRQLIKVLSN-RAFIGICNNNCMAFYGFLES Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2659.fasta_al_trimmed; alignment length = 112] Allma1 TTRTTRHLSTSTEAKRRRLLWHSRKRGILECDLLLSTFAA-QHLSTLSADKLDAYDALISKEDWDIYYWATLK---KP-VPEH-VDTEVMALIQQVAKNEARTI-LKMPELA Ashgo11 MLRFSYGLAPAREQQRARLVYQSRKRGILETDLLLSGFAA-KYLKHMTAEELNEYDELL-NEDWDIYYWATKNSDASP-LPEKWQHSKILRKLQAYSENKDKQI-LKMPDLS Aspfu1 ---------------------------------------------------------------------------------------------------------------- Aurde31 MLRTARYTHPTPETLRARLVYQSRKRGTLECDLLLSTFAD-ENLRAMSDAELREYDELL-NEEWHIYYWAIGK--RNP--PERWVGSHILERLKTHARNDAKVI-RRMPDLR Batde5 ------------EQKRSRLVWQSRKRGILETDLLLSTYIQ-QALPTMEDAQLQEYDSLL-DEDWDIYYWCTGA--KEA--PERIKDMSIFDGLVEHCKNKRKLV-LRMPNV- Botbo1 ------------DAMRARLVYQSRKRGTLESDLLLSTFAK-DHLPTMDEGEMRQFDKLM-DEDWDIYYWAIGK--RDP--PPRWTDSPLLAKLKIHAKNEGKVV-RRMPDLA Botci1 ---------------------------------------------------------------------------------------------------------------- Caeel MTSRITSLRSLTDAKRARLLYQSKKRGILENDILLGDFAE-QNLKKMSEPELKAYDKLINGEEWDLFYYLSNK--KSP--PEDVESCQVYQKVKKFVDDKRVPKS------- Canalb1 MLSKSRSFSQSSEVKRARLLYQSRKRGILESDLLLSRFAD-KYLKTMTMEELDEYDKLL-DEDWDIYYWATKNYKITP-LPDKWKDSKILKEIQKIANNDEKVI-MRMPELK Cangl MLRITKLVPTIKDKKRARLIYQSRKRGILETDLLLSGFAA-KHLRSMTNEELDEYDALL-NEDWDIYYWVTKNYKTSP-VPERWKNSEILKKLQDFSENKEKKI-LRMPDLE Capow ALRSASGLANMQQVKIARLLYQTRKRGILENDLLLSTFFA-EHANALSDAQLQTFDKLL-DQDWDIYYWITKA---RP-VPPEFDT-DVMALIQAHTL-ARRNGPLRQPSTP Catan2 ------------DAKRARLVWQSRKRGILESDLILSTFAA-KQLATLSPELLDAYDKLL-EEDWDIYYWATEK---KT-VPEH-INKEVMSRIQQVARNEGRKI-LKMPELD Cioin VVRCTNRFKNSQTKKRARLHWQSRKRGISENCLIFSTFAA-KYLNSFSPEQIEIYDKIL-NKDWDVYYWMVGT--KNV--PNEYQS-EIMDMLQEHCRNNKKEERFIQPALE CocheC53 ---------------------------------------------------------------------------------------------------------------- Coere1 ------------ETTRRRLLYQMRKRGILETDLLLSTFAA-QHLSSLSRAELGDLDSLL-SNDWDIFYWATGK--TQP--PESIWSMPVFQKLRDHASKRGHSI-VRMPDL- Conco1 MIRPLLKLSNLKEQLRARLVYQCRKRGILETDLIMSTFAT-KYLAQLSVENCKKLDNFL-DYDWDIYYWVTDA--KEP--PVEVSELEVFQLIREHAKNKDKNI-LRMPDL- Conpu1 -MLSLRAFSACREKMRARLVYQSRKRGTLESDLLLSTFAR-DYLKEMSAEDMREYDKLL-DEDWDIYYWATYG--REP--PAKWADSRILAKLREHAKNEGKET-RSMPSL- Copci MFSTIRTITTTPSSLRARLVYQSRKRGTLETDLLLSTFAQ-ENLAKMSVPELKEFDKLL-DEDWDIYYWCTGK--RTP--PERWAKSELLEKLRVHAQNEGKVV-RRMPDLS Croqu1 -MQAIRRFATSADSLRARLVYQSRKRGIVEMELLLSTFIDGGKLADWPLEKLRTYDRFL-KLDWDIYYYVIKR--LDPPATSEWRNSALINELRTHTANRAKRI-RKMPDLP CryneH991 VLPRVRSISTTNKTLRARLIYQSRKRGTLETDLILSTFAR-DELPNMGFEEMKQFDTLL-DEDWDIFYWSVEK--REP--PARWKGTPLLEKLKKHAKNEGKVV-RMMPELM Crypa2 ---------------------------------------------------------------------------------------------------------------- Debha1 MFRN-RNISSSGDVKRARLVYQSRKRGILESDLLLSRFAK-RYLSGFSQEELDEYDKLL-DEDWDIYYWATKNYDVTP-LPDKWKNSKILKLLQEDAENKEKEI-LRMPEL- Dekbr2 ALKGQLKYRSTKETKRRRLLYQSRKRGILETDLLLSRFAD-RYLIKMTEAELNEYDKLL-DEDWDIYYWATKNYKITP-LPDRWKHSKVSRMLQESSNNGDKVI-SRMPELK Dicdi MFKSIKNVEDESEKLRKKLLYQSKERGMLENDLLLGSFAT-LNIHKLTESQLRDYNLLL-QQDPDIFNWILKK--AEV--PEEFET-EVLKLVQHHCKNDPLGYTRK----- Dmel MLRQFRLASNLDETRKQRLLYQSRKRGMLENDLLLSTFVA-KHLKDFNAEQTAEYDQLI-NGDWDIFYWATDT---KP-TPPQFDT-EIMRLLKEHVKNHEKVQRIRQPDL- Enthi ---------------------------------------------------------------------------------------------------------------- Falba FTRLAFRLYSTSDNKRKRLLWESRKRGILENDLILGTFAK-RHLDELDDTELEQYDRLL-DEDWDIYYWATER---RP-VPPEFADTRVLALIRHIARNPEGEV-RAMPEL- Fomme1 MFRRLRPLSSTTEKMRARLVYQSRKRGTLESDLLLSTFAA-LKLGTMSEEELKEYDSLL-DEDWDIYYWATEK--RPA--PERWANSPLLAKLRQHARNDGKEI-RRMPNLS Fusgr1 ---------------------------------------------------------------------------------------------------------------- Galma1 MFQRLRHISSTSDTLRARLVYQSRKRGTLESDLLLSTFAR-DNLSTMSEAEMMEYDKML-DEDWDIYYWSTGK--RTP--PERWANSPLLEKLRVHARNEGKVV-RKMPPL- Ganpr1 ------------DTKRARLVYMSRKRGIKETDLLLSTFAK-KYLGTFDEQMLDEYDALL-EEDWDIFYWSTG---VRP-LPDDIASMKIMPILVEHCKNRDREV-LRMPDE- Gloin1 MIR--RNNSNNSEKKRSRLLYQSRKRGILETDLILSTFAS-KYLKTFNEQELKEYDELL-DTDWDIYYFTIDK--KPI--PDKWKNSIIFNKLKQHVKNEGRIT-LRVPDL- Hisca1 ---------------------------------------------------------------------------------------------------------------- Klula1 MLRTVKQCRSLHDKKRARLIYQSRKRGILETDLLLSRFAA-KYLKEMTPEQLEEYDQLL-NEDWDIYYWATENYSITP-LPDRWKNSNILKQLQEFSKNKDREI-LSMPDLS Lacbi2 MLQSLRLISSTRDTLRARLTYQSRKRGILECDLLLSTFAR-EELSTMSHADLMEYDKFL-DEDWDIYYWSTGK--RTP--PERWANSPLLDKLRTHARNEGKVV-RRMPSL- Lenti61 MYHRGRSFSTTTEKMRARLVYQSRKRGTLESDLLLSTFAK-DRLGSMSKDELHEFDKLM-DEDWDIYYWATGK--KAP--PPRWEGSNVLKQLAEHAKNEGKVV-RRMPDLS Malgl1 -----RMISRTVPRLLARLQYQCRKRGTLETDLLLSTFAH-EELRRLPDDELHELDRLL-DEDWDIFYWCTDR---KP-VPERWHASRLGYRLRIHTRNDQRSV-RRFPSLK Mellp23 ------------ESLRARLVYQSRKRGIVEMELLLSTFIDGGKLEEWNIEQLQTYDRFL-KLDWDIYYYVIKK--LDPPAESEWKDSQLVNQLRIHTANRAKQI-RMMPSLS Mnele MLKSVRTFSEDNEALRARLTYQSRKRGIAENCLILSTFFS-EQGPNLPRKIVDQFDILI-NTDWDLYYWMTGK--DQP--PPPYDN-EVMKMLIEFTQNKEMKDRTQQPDL- Monbr MWRAT-SVTLSGDQLRARLVYQARKRGIKENDLIFSTFCH-KYLDQLSRPQMEQLDIIL-NEEWDMFNWLSGT---RP-APEYLKELELFGALVDHTQNRSKEVRVTMPPLK Morel2 ILRKARSFASKSQTIRARLTYQSRKRGILETDLILSTFAK-EFLNKLSLEECRRLDKFM-DEDWDIYYWVTGK--KEV--PEKWREDPVFDMIVKHAKNEGRVV-RSMPAL- Mucci2 -MS--RSISTLRENKRRRLTYQSRKRGILETDLLLSTFAK-VWLPQFNREQLEEYDKLL-DEDWDIFYWSTNK--KPV--PQKWQNSKVLEMITQHAKNEDKKV-LRMPNLE Mydma FL---SFVKESQDVLRSRLLYQSRKRGMSENGILLSTFAS-FYLNRFTRRQLEEFDKII-NKDWDIFYWILGK--KET--PHEYNS-EVMDLLKSFSRNQDMEARYRQPDLI Neucr2 ---------------------------------------------------------------------------------------------------------------- Orpsp11 ---------------------------------------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------- Phybl2 ------------ETKRARLAYQARKRGILETDLLLSTFAK-IHLPLFTMDQLVEFDRLM-DEDWDIFYWATDK--KTL--PARWQGSKVLDSLRAHAKNEAKVV-LRMPDLV Picst3 MLRN-RSISSSVEIKRARLIYQLRKRGILESDLLLSRFAK-KYLNEFTEAELDEYDRLL-DEDWDIYYWATKNYDVTP-LPDKWKDLKILKMLQEDAKNDDREI-LRMPELD Plicr1 --MSIRMLSTTSSTMRARLVYQSRKRGTLESDLLLSTFAR-DFLADMQEEELREYDKLL-DEDWDIYYWATGK--RER--PERWANSAVLEKLAVHARNEGKVV-RRMPALS Polpo MFTNKRLYSSSNDILRKKLIYQSKERGMLENDLLLGSFAS-KYLNDFDHNKLVEYDNII-QQDPDIYNWALNK--QDI--PEELNT-EVMKLLQHHCQNNPLGYPKN----- Pucgr2 ---------------------------------------------------------------------------------------------------------------- Punst1 MYRTLRQLSRTPATKRARLVYQSRKRGTRETELLLSTFAQ-EHLAAMSADEMTQFDKLM-DEDWDIYYWATGK--KTP--PARWSESAVLEKLKKHAKNEGRVV-RRMPEL- Rhior3 MLR--KTLVCLQEDKRRRLTYQSRKRGILETDLLLSTFAK-TWLPKFNADQLKEYDQLL-DEDWDIFYWATEK--KPI--PEKWQKSEIFQLIKQHAKNEEKKV-LRMPDLE Rhoto1 MLRSLRVCSDSSETLRKRLVYESRKRGILEMDLILSTFAK-ERLPEMNDRQLREYDRFL-TLDWTIFYYVTGK--AEA--PEPWKSSQVLHELRHHSANKGKTV-RRMPDLE Rozal11 -----RHMYKLTEKRMSRLVYQSRKRGILENCLMLGQFAE-RNLKEMSNDDIVEYERLL--EDWDIYYWIVGE--RKV--PNEFE--RVIGKIRTSVEEGKNKMKETHSQIK Sacce1 ---MHKIINSQTDKKRARLIYQSRKRGILETDLLLSGFAA-KYLKKMNEEELEEYDSLL-NEDWDIYYWATKNFKTSP-LPDKWANSKLLKQLQEFSENKEKEI-LSMPDLS Salro VLRAPSAVAGTGDHKRARLLYQSRKRGIKEMDLILATYAD-QYLDTMTEQQLEEYDSIL-NDEWDMFKWLTGK---EE-LPEYLQGSGVMQHLMEFTKNPNKEQRAHMPPLR Schco3 MFASVRSISYSAEKMRARLVYQSRKRGTLESDLLLSTFAR-DNLSTMTEDEMREYDKLL-DEDWDIYYWATGK--RTP--PERWQESQLLKKLAVHAKNEGKVV-RRMPSL- Schpo1 MLRKTRCMNRM-DAMLARLKYQSRKRGILETDLLLSNFAK-DQIDKYPVSLLREYDQLL-DEDWDILYWCSGE--REA--PEKWKSSQVFKELSKYCRSQRNHT-LRMPELF Sorma ---------------------------------------------------------------------------------------------------------------- Sphar TFRTLHTFASTLENKRKRLVYQVRKRGMLENDLLLSTFAR-EYLNDMDGAELHLFDKLL-DEDWDLYYWLTDK--KEV--PEEFNHS-VFQKLKAYSKNERAEA-LRMPHME Spipu1 MIHKARAF----STKRARLVYASRKRGILETDLLLSTFAG-EHLSELSREELEEYDNLL-EEDWDIYYWVTGT--EGKIVPERVQQMKVFPKIVEHAKNRGRKI-LRMPDLK Sporo1 ------------ETLRKRLVYESRKRGILEMDLILSTFAK-ERLAQLNDRELREYDRFL-TLDWTIFYYVTGK--AQA--PEPWKSSKVLQDLLNHSANRGKEV-RRMPDL- Stehi1 --------------MRARLVYQSRKRGTLESDLLLSTFAR-EWLGGMEEAELREYDKLL-DEDWDIYYWATKK--RAP--PERWANSSVLEKLVVHARNEGKAV-RRMPDLN Tapde11 MFKSLRTFSSARETKRARLLWQSRKRGILETDLLLSTFAA-KQLERMSMDELILYDQLL-DEDWEIYYYATSK--KQP--PEKFRGSRLIEDLIQHVKNEEKET-RRMPSLK Thetr ---------------------------------------------------------------------------------------------------------------- Treme1 --MYLRSLSNSTKTLRARLVYQTRKRGMLEGDLLLSTFAR-DQLGFMTLDELREFDQ-A-NEDWDIYYWSIGK--KQP--PERWATTSLLEKLRKHAKNEGKVV-RVMPDL- Trire2 ---------------------------------------------------------------------------------------------------------------- Umbra1 MLRSARAFQHVSETKRSRLVYQSRKRGILETDLLLSTFAK-KFLPNFDMEQLLQYDALL-DEDWDIFYYATFK--KDV--PEHLQSNQALQMLQQHAKNEGKVI-LQMPSLS Ustma22 TIRNVQSLDKQSETKIARLIYQTRKRGTLETDLLLSTFAK-KELKNLPDAELDEFDRLL-DEDWDIFYWCTQR---KP-IPARWAHSKLGHRLVAHTRNDEKAV-RWMPEL- Walse1 MLKSIRLLSTTNPIKKSRLLYQSRHRGTLESDLILSTFAQ-KYLSQMDTKELNDFDKLM-DEDWDIYYWSLNR---KP-LPQRWENNPIIDKLKLHVKNEEKVS-KRMPPVQ Zygro1 LPRISFLVSTTHDRKRARLIYQSRKRGILETDLLLGGFAA-KYLKEMTPEQLAEYDSLL-DEDWDIYYWATKNYETSP-IPEKWKNSELMKKLQVYAENKDKKI-LRMPDLK [Cluster2660.fasta_al_trimmed; alignment length = 93] Allma1 FARASF-SVAAVRPG-AKPGTVPTELDQATGLERHEYLSELEGRDAFDKPLEMTHGTVANPIVVKSRYVGCSGPAESHE--NIWIRVRCPECG Ashgo11 SLRQSF-STSRAIKG-AAEGQIPTELEQATGLARLEFLGKLEGVEIFDQPLDSSRGTMKDPILVDSRYVGCTGPAGSHS--TMWLKPRCWECG Aspfu1 ARRAPF-SSSVVRPG-AKPGTVPTDVEQATGLERLELIGKMQGIDIFDRPLDASRGTLDNPIIVKSQYAGCTGPADSHH--TVWLTVRCGECG Aurde31 ASRPRL-SVTARAKG-APAGEVPTSQQQATGLERLQLVGEMEGQEFFDDPLYIDRGTLKDPILVKSRLVGCTGPVESHE--TIWLNCRCPECG Batde5 --------------------QIATNYELSAGVERYEYLKMLKGEDPWEQPIVLTEGTIKKPIIVRGRYVGCTGPADSHE--AVWLTVRCPHCG Botbo1 LARCQF-SSTLRADG-ASAGTVPTDENQATGLERLQILGNLEGIDVFDKPLEMTRGTVDEPIKIHSRVIGCTGPADSHD--TLWLNLRCPECG Botci1 ARRAAF-TSSIIRPG-AAPGTIPTDLDQATGLERLEILGKMQGVDIFDKPLDASRGTLDNPIIVKSQYAGCTGPVDSHV--TIWLTMRCPECG Caeel --------------------------------------------------------------------------------------------- Canalb1 TFRIAL-STSRVLPG-AKEGTIPTDYEQATGLQRLELLGKREGVDVFDMPISEGKGTMQDPYLVPTRYVGCKGPEQDHK--PYWMKVRCWQCG Cangl MLRSTL-WTSRVLPG-GKEGEIPTELEQATGLARLELLGKLEGIDVFDKPLDASRGTMQDPIVVDSRYVGCTGPAGSHT--IMWLKPRCWECG Capow AIRAP--AVAAVRPN-FSIEELPTNDQQATGPERKELAHHPHGT----DPFGREHGTKTNPIVIPSRISACMGEGTPHD--MAWFVARCNHCA Catan2 AIRPRC-SVATVRPG-SKPGTIPTELEQSTGPERFEYLRELEGKEAFDKPLEPTHGTPAQPIVVQSRYVGCTGPVDSHD--TLWIRVRCPECG Cioin --------------------------------------------------------------------------------------------- CocheC53 ARRAAF-TTSFVRPG-AKPGTVPTDAEQSTGLERLEILGKMQGIDIFDRPLDASRGTMENPITVNSQYVGCTGPADSHN--VLWITLRCMECG Coere1 AARLSF-STGAVRPG-PKPGRVPTNFELATGDERKEYLATLEGKQYYDEPLYLDKGTRDDPTIVPSRLIGCQGPGEDHE--LLWIRVRCRECG Conco1 FVRSAF-SVATPVSG-AQSGKVPTDIEQAVGLERVELLAEMEGREFWDAPLEMTHGTKKNPIVIESRYVGCTGPADSHD--TIWLNVRCPECG Conpu1 AARPTL-SVSAVRPG-SKAGEVPSDETQATGLERLQLLGEMQGVPAFDEPLDSSRGTLEDPIKVFSRVVGCTGPADSHE--VHWFKVRCPECG Copci AVRSSF-S-TTQRSG-GKPGQVPTDIEQATGIERLQLLGELEGVNVFDSPLDSSRGTKADPIKVLSRMIGCTGPADSHD--VTWFMVRCVECG Croqu1 SLRANF-TSSSIAPG-AKPGTVPTDLEQATGIERYEILARMEGHEPFDKPLAVPHGTLTNPVKVFSRIVGCTGPVDSHD--TIYMKVRCHECG CryneH991 LRRTLF-SISAARPG-AKAGEVPNDENQSTGLERFELLGNLEGVDVFDKPLEVTRGTVEDPIPIYSRQIGCTGPVDSHD--TIWLNVRCPECG Crypa2 ARRAAF-ATSMIRPG-AKPGSVPTDLEQSTGMERLEILGKMEGVDVFDRPLDASRGTMKEPILVRSQYAGCTGPVDSHG--VIWLTIRCPECG Debha1 TIRFAL-STSRILPG-AKEGTIPSDLEQATGLERFELLGKMEGIDVFDNPIFEGSGSMKDPYLVPTRYVGCMGGGDDHK--PYWMKVRCWQCG Dekbr2 MLRQTF-STSVIATG-AQKGEVPTDLEQATGLERLELLGKLEGVDIFEKPLDTSRGTMQNPILIDSRYIGCTGPAGSHI--VMWLKPRCWECG Dicdi --------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------- Falba STRTAF-ASAAAGPAYFEHGEIPRNIDLLTGNSRIEYIRMLQGK--FDEPNPNPHGTKENPIIIPCAIVGCQGDEPGYM--EYWTMPRCQECG Fomme1 STRSLFISTSRVLPDNTPPDAIPTDEQQATGIERFQLLGRMEGVDVFDHPLDSSRGTMKDPIKVATRLIGCTGPADSHE--VVWLDARCPECG Fusgr1 ARRVAF-VTSVARPG-AAPGTVPTDLEQSTGLERLEILGKMEGVDIFDRPLDATRGTMKDPIMVRSQFAGCTGPADSHS--VTWLGIRCPECG Galma1 AARPSF-S-TSVRPG-AKPGTVPTDIEQATGLERLQLLGEMEGINVFDSPLDSSRGTKKDPVLVPSRIIGCTGPAESHD--VLWFTLRCTECG Ganpr1 -----F-S-----PGPSEPGKVPTNLEVAVGLERYEYLETLDGKVPFELPLIVTEPTKKNPLVVSGAYVACTGPADAHE--PIWLTLRCPTCG Gloin1 ALRSTF-SVLSPRPG-AKPGTVADDIDQATGIERAELLSKLEGKDIYDSPLKITAGTKKDPVMVKSRFVGCTGPVDSHE--TVWLGVRCPECG Hisca1 ARRTPF-SASVIRPG-AKPGTMPTDYEQATGLERLELLGKMHGIDVFDRPLDSSRGTLNDPIIVKSQYAGCTGPADSHS--VVWLTVRCSECG Klula1 SLRQSF-ATTKVAPG-AKDGEVPTELDQATGLARLELLGKLEGIEVFDKPLDSSRGTMENPIIVESRYVGATGPAGSHN--VMWLKPRCWETG Lacbi2 AARASF-S-TSVRTG-GKAGEVPTDLEQATGLERLQLLGELEGIDVFDSPLDSSRGTKADPILVPSRMVGCSGPADSHD--VLWFMLRCTECG Lenti61 -------------EG-AKPGEIPTDVNQSTGLERLQVLGALEGVEVFDKPLDSSRGTLADPIKVFSRVVGCTGPAESHE--LIWFTLRCPECG Malgl1 TLRAPI-STSPLREG-PKPGEIASDEQQSTGLERFELMGRLQGVDVFDSPLDASRGTVANPIKVRSQVIGSTGPADSFD--TVWMKLRCPLSG Mellp23 QLGARF-TSSSIQVG-AKPGTVPTDLEQATGIERYEILARMEGLEPFDKPLAVPHGTLADPVKVFSRIVGCTGPVDSHD--TIYMKVRCGECG Mnele TTKMSF-------PG---------------ALERMELIPEWEGKLGWEDPWCVEGADHTRPHILYTRVVGCVDMDDQHY--INYLLIRCKDCG Monbr --------------------------------------------------------------------------------------------- Morel2 TLRAAF-SALSVRPG-AAAGSTPTDLDQSTGLERAELLGKMQGKDIFDAPLEVHVGTKANPTIIHSRYVGCAGPGETHE--VQWLLIRCDQCG Mucci2 AIKAAF-SVLGARPG-GKAGEVPTDLEQATGLERQELLAKLEGKELFDEPLNMTHGTPKNPIVVQSRFVGCTGPVESHD--VIWINLRCPECG Mydma --------------------------------------------------------------------------------------------- Neucr2 ARRATI-ATTVVRPG-AAPGTVPTDLEQATGLERLEILGKMEGVDVFDKPLDASRGTMENPISVRSQYAGCTGPADSHN--VIWLTMRCPECG Orpsp11 --------------------------------------------------------------------------------------------- Pench1 ARRSPF-SSSVIRPG-AKPGTIPTDLDQATGLERLELIGKMQGIDIFDRPLDASRGTLQDPIIVNGQYAGCTGPADSHQ--VTWLTVRCLECG Phybl2 --------------G-GKAGEVPTDLEQATGLERIELLAKLEGKELFDEPLQVTHGTPKNPIVVESRFVGCTGPVESHD--VIWINLRCPECG Picst3 SLRIAL-SSTRILPG-AKAGTIPTDLDQATGLERLEILGKREGIDVFDNPIYEGKGTFEDPLLVPTRYVGCRGDGEDHK--PYWMKVRCWQCG Plicr1 ATRASL-SATAARPG-AKAGEVPTDFEQATGLDRLQVLGEMEGVEVFDEPLDASRGTLADPILVPSRIVGCTGPADSHD--VHWFQLRCPECG Polpo --------------------------------------------------------------------------------------------- Pucgr2 SLRGSL-SVSRIAPG-AKPGTVPTDLEQSTGIERYEILSRMEGHDPFDKPLAVNHGTLDNPVKVFSRIVGCTGPVDSHD--TLYMKVRCSECG Punst1 VARSAL-STTALRPG-GKPGEVPTDEEQATGLERLQLLGELEGVDVFDEVLDSSRGTLADPVKVPSRLIGCTGPADSHD--VIWMNLRCGECG Rhior3 AIKAAF-SVLGARPG-AQPGQIPTDLEQSTGLERMELLATLEGKQLFDEPLNMTHGTVKNPIVVKSRFVGCTGPAESHD--TIWINLRCPECG Rhoto1 APRALF-LTSAIREG-GKAGEVPTDLQQATGLERFELLHKLQGEEAFSEPLDASRGTLKEPVMVFSRIVGCTGPADSHD--TVHMVVRCPECG Rozal11 --------------------------------------------------------------------------------------------- Sacce1 SLRQSL-CSSRYLPG-AKEGTVPTDLDQETGLARLELLGKLEGIDVFDKPLDSSRGTMKDPIIIESRYVGCTGPAGSHT--IMWLKPRCWECG Salro --------------------------------------------------------------------------------------------- Schco3 AARASL-STTARVPG-GKPGEIPSNWEQATGLERLELLGDLQGIKVFDSPLDSSRGTKKDPIRVPSRVIGCTGPADSHH--VLWFHVRCTECG Schpo1 AVRSTF-VSASIRPG-GRDGEVPTDLEQATGLERYELLSELSGRDAFDKPLDASRGTLTDPIMVTSRHIGCTGPSGSHN--LIWMTVRCPECG Sorma ARRATI-ATTVVRPG-AVDGTVPTDVEQATGLERLEILGKMEGVDVFDKPLDASRGTMENPISVRSQYAGCTGPADSHN--VIWLTMRCPECG Sphar VLRTT--SMSAISAG-----GIVSGDDQAVGLERYQAKGNMD--PFFK-DLRCYHGTEENPHLVPSRIIGCTGSPRPHE--TLWYNVECNECG Spipu1 -----I-SLSARKPGFREEGQIPTNWELMAGNERYEYMQRLAGKEPWEKPIVMSTGTVANPTIIKGRYIACTGPADSHE--AIWLTIRCPHCG Sporo1 -------------PG-GKTGEVPTDIEQATGLERFELLHKLKGEEAFSEPLQVDRGTLADPIMVFSRIVGCTGPVDSHD--TILFPVRCPECG Stehi1 AIRAAI-ATSAVRPG-AKKGEVATAENQSTGLDRVESLGLLQGVEVWDNPLDSSRGTKKDPIKVISRTIGCTGPADSHD--IQWMVLRCHECG Tapde11 --------------------------------------------------------------------------------------------- Thetr VSRTA--SVAAAWPA-----GIPSSMDVATGRE---TEGERHGAEVLA-SQAATHGTKENPVKVLSRIVGCTGCSSIHENGVLWWRLEC-PCG Treme1 -------------PG-GKPGEVPTDEEQSTGLERFQLLGKLEGVDVFDKPLEMTRGTVESPIPIYSRHVGCTGPADSHD--TLWLTVRCPECG Trire2 -----F-LT----PG-AQPGTVPTDLEQATGLERLEILGKMEGVDVFDRPLDSSRGTLDDPILVRSQLAGCTGPADSHG--VIWLGLRCPECG Umbra1 AVRAIF-SVL---PG-AQPGTVPTDLEQATGLERLELLAKLEGKELFDEPLNMTHGTKQNPIVVKSRFVGCTGPAESHD--TIWLTVRCPECG Ustma22 ALRVAF-TSSALREG-AKEGEIPTDEQQATGLERFELLGKLQGVDVFDEPLQMTHGTTEKPIKVKSRIVGCTGPADSHD--TIYLHLRCPECG Walse1 VSRQSY-SAA---PG-AEDGTVPTDEDQATGIERMELLAKAQGSELFDQPLKVDRGTMKDPIIVPSRIVGSTGPVDSND--TVWLTLRCPESG Zygro1 SLRQSF-STSRVFPG-AKEGTVPTDLEQATGLERLELLGKLEGVEFFDKPLDSSRGTMADPIVLESRYVGCTGPADSHT--IMWLKPRCWECG [Cluster2662.fasta_al_trimmed; alignment length = 135] Allma1 D-FYVRYYVGHTGRYGHEFLEFELRYRNNSNY--KNDT--MIRKEVSPMILKELQRIVAQSEIMKEDDANWPEPNGKQELEIVSGKDHICFTSKIGSLVDIQNSSDPEGLKAFYYLVQDLKFVFS-LISLHFKIK Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 EPFYLRYYSGHSGRFGHEFLEFDVRYANNSNY--RNDS--LIRKEVSSAMIQEVKRIIKESEIMKEDDSKWPQKNGRQELEIRLGNEHISFTAKIGSLVDVTESADPEGLRVFYYLVQDLKLIFS-LISLHFKIK Aurde31 DPFYFRYYTGHVGKHGHEFLDFELRYANSSNY--RNDT--LIKKEPSQLVVSEFKRIIEASDIMREDDAKWPKKNGKQVLEIRLGNNHISFTAKIGSLSEVNDTEDPEGLRVFYYLVQDLKFIFS-LITLHFKIK Batde5 D-FYVRYYVGHMGKFGHEFLEFEMRYANNSNY--KNDT--MIRKETSASVMSELRRIIKDSEITKEDDQKWPEPDGRQELEIVIGDEHISFTAKIGSLVDVQKSDDPEGLRVFYYLIQDIKLVFS-LISLHFKIK Botbo1 DPFYLRYYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVESSEITKEDDTNWPKKNGKQELEIRVGDDHISFTAKIGALVDVQDSEDPEGLRVFYYLVQDLKFIFS-LISLHFKIK Botci1 EPFYIRYYSGHQGRHGHEFL-------------------------ISSLLVEEIKRIIKTSEIMKEDDSKWPQKNGRQELEIKIGSEVISFTAKIGSLVDVTESQDPEGLRVFYYLVQDLKLVFS-LIALHFKIK Caeel D-FYVRYYVGHKGKFGHEFLEFELRYANNSNY--KNDT--MIRKEVSESVLSELKRIIEDSEIMQEDDDNWPEPDGRQELEILYKNEHISFTGKIGALADVNNSKDPDGLRSFYYLVQDLKLVFS-LIGLHFKIK Canalb1 --------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------- Capow STFHLRYYTGHKGKFGHEFLEFELRYANNTHY--RGET--IIRKQVSRAVLQELKRILADSEITREDGNMWPKPEGKQELDIEMDGVRKSFVSVIGKLSDVDNSNDAEGLKIFFYLVQDLKFVYS-LISMHFKIN Catan2 --------VGHTGRYGHEFLEFELRYVNNSNY--KNDT--MIKKEVSPLVISQVRRIVQDSNIITFDDEKWPEPNGKQEIEVVLGQDHISFTCKINTLNEVNQAQDPDTLRDFHYLVQDLKLIFS-LISLHFKIK Cioin --FYLRYYVGHKGKFGHEFLEFELRYANNSNY--KNDT--MIRKEVHKAVLEELKRVIDDSEIMKEDDTLWPTPDGRQELEIVLGKDHISFTSKIGSLVDVTDCKDSDGLRCFYYLVQDLKMVFS-LIGLHFKIK CocheC53 EPFYLRYYSGHQGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSDTLVAEIKRIVKESEILKEDDTKWPQKNGRQELEIRLGSEHISFTAKIGSLQDVSESSDPEGLRVFYYLVQDLKLVFS-LIALHFKIK Coere1 DDFYIYFYTGHKGRFGHEFFRFELKYANNSNY--RRDS--IIRKNMSPTLITVMKKIIEDSEIMKEDDKRWPQRDGRLQLEIRMNGKSINFTAKISSLADTVNTDDPEGLRVLYYLVQDFKLILS-LISFHFKIK Conco1 GDFYIRYYAGHEGQDGHEFLEFECRYANYSNY--RDEN--LIRKEISELMLSEIKRMVLESGILDLNDEDWPQEAGKQELEIQTSNIHISFTAQIGSLLDISESKDPDGLKQFYYFIQNLKIAFS-LISAHFKVK Conpu1 DPFYLRFYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEIGPLVIKELKRIVESSEIIKEDDTNWPKKNGKQELEIRIGNDHIAFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLRFIFS-LISLHFKIK Copci DPFYLR--TGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVEASEITKEDDSNWPKKNGKQELEIRIGNDHISFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Croqu1 DAFYVRYYSGHMGRYGHEFLEFELRYANNSNY--RNDS--LIRKELSPMTISELKRIVGESEIVKEDDHNWPKKNGKQELEVRLGDTHISFTAKIGSLVDIQGSDDPEGLRVFYYLIQDLRFVFS-LISSHFKIK CryneH991 DKFYLRYYTGHQGAHGHEFLEFEIRYANNSNY--RNDS--LIRKEVSPAVVDELKRIVRESEITKEDDVAWPRKNGKQELEVRIDKEHISFTAKIGALAEVNDSSDPDGLRVFYYLIQDLKFIFA-LIQMHFKIK Crypa2 EPFYLRYYSGHSGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSLVIDEIKRIIKTSEILKEDDGKWPQKNGRQELEIKVGGEHISFTAKIGSLVDVTESADPEGLRVFYYLVQDLKLVFS-LISLHFKIK Debha1 --------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------- Dicdi DDFYLRYYVGHKGKYGHEFLEFELRYANNSHY--KSEN--LIRKEVSDGVISEIKKVILDSGIMLEDDKNWPEPDGKQELEIVFKDEHISFTTKIGSLMDVEKSDDPEGLKVMFYLIQDLKLVFS-LIGLHFKIK Dmel D-FYLRYYVGHKGKFGHEFLEFELRYANNSNY--KNDT--MIRKEVHQSVMEELKRIIIDSEIMQEDDLPWPPPDGRQELEIVIGDEHISFTSKTGSLVDVNRSKDPEGLRCFYYLVQDLKLVFS-LIGLHFKIK Enthi NHFYLRYYNGNHNQYGKEYIKFELKYCNQSRY--RNET-EIIKK-LTRVVMKEIQDIISQSHILIQTDAHWPNKISRQELEIEMNDIHIFFTSKFGTLNEIRQSEDPQGLLIFYNFINDLILLTT-LTKSHSNIH Falba ETFYVRYFMGHNSRYGLEFMEFEMRYVNQSKY--RRDK--IIRKELSKASIQALQQIVAESDIVEEDDKLWPRPNGKQELEVVLDNKHISFTSMITSMREIQDEKDFEGLQTYYYLIQELRFMNA-VISLHFKII Fomme1 --------TGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEIGPLVVKELKRIVESSEIIKEDDQNWPKKNGKQELEIRVGNDHIAFTAKIGSLVDVQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Fusgr1 EPFYLRYYSGHMGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSVIVDEIKRIIKTSEITKEDDSKWPQKNGRQELEIRIGNDHIAFTAKIGSLVDVTESADPEGLRVFYYLVQDLKLVFS-LIALHFKIK Galma1 DPFYLRYYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVEASEITKEDDTNWPKKNGKQELEIRVGNDHIAFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Ganpr1 E-FYVRYYVGHMGRFGHEFLEFELRYANNSNY--KNDS--MIRKEVSPSVVNELRRVIQESEIMKEDDKLWPMPDGRQELEVVLNNEHISFTSKIGSLADVQDSKDPEGLRVFYYLVQDLKLVFS-LIALHFKVS Gloin1 EEFYVRYYTGHMGRYGHEFLEFECRYANNSNY--RNDS--LIRKEVSPLMMKELKRIIQESEIMKEDDQKWPKKNGRQELEIRLGNEHISFTAKIGSLVDVQESDDPEGLRVFYYLVQDLKLVFS-LIGLHFKIK Hisca1 EPFYVRYYSGHSGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSLMIAEIKRIIKESEIMKEDDSRWPQKNGRQELEIRLGNEHISFTAKIGSLVDVTESAPP---------------------------- Klula1 --------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 DPFYLRYYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVEASEITKEDDTNWPKKNGKQELEIRVGNDHIAFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Lenti61 DPFYLRYYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVESSEITKEDDTNWPKKNGKQELEIRIGNDHIAFTAKIGSLVEVADSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Malgl1 ----------MCGTWNAEYLT--IRVGTATSF--LNSS-------VDVSDMQTTATTVMTRSFAKK-------------------------TAKLGSLLEVQDSEDPEGLRVMYYLVQDLKLIFS-LISLHFKIK Mellp23 DAFYVRYYSGHMGRYGHEFLEFELRYANNSNY--RNDS--LIRKELSPMTISELKRIVGESEIIKEDDHNWPKKNGKQELEVRLGDTHISFTAKIGSLVDIQGSDDPEGLRVFYYLIQDLRCVFTDFIS--FQNQ Mnele D-FYLRYYVGHKGKFGHEFLEFELRYANNSNY--KNDT--MIRKEVSVPVLKELARIIEEAEIMYEDDKMWPAPDGRQELEIVHKNQHICFTSKIGSLVDVNSSKDPDGLRAFYYLVQDLKFVFS-LIGLHFKIK Monbr D-FYVRYYVGHKGKFGHEFLEFELRYANNSEY--KNDS--MIRKEVSKAVLEEIKAIIEDSEITKEDDNLWPMPDGRQELEIVYGNDHISFTAKIGSMIEVNDSKDPEGLRTFYYLVQDLKFVFS-MISLHFKIK Morel2 EEFYVRYYSGHQGRYGHEFIEFECRYANNSNY--RNDS--LIKKEVSPLMIKELKRIIADSEVMKEDDHKWPKKNGKQELEIRFGNEHVSFTAKIGSLVDVQGSEDPEGLRVFYYLVQDLKLVFS-LITLHWKIK Mucci2 SEFYVRYYSGHRGRYGHEFLEFECRYANNSNY--RNDS--LIKKEVSAAVIDELKRIIEDSEVMKEDDSQWPTKNGSQEIEVRLGNEHISFTSKLSSLVEVQDSKDPDGLRAFYYLVQDLKFVFS-LISLHFKIK Mydma E-FYCRYYVGHKGKFGHEFLEFECRYANNSNY--KNDV--MIRKECSKSVLEEVKRIIDDSELLKEDDALWPTPDGRQELEIVMGDEHISFTSKIGSLIDVNQSKDIEGLKCFYYLVQDLKLVFS-LIGLHFKIK Neucr2 EPFYLRYYSGHSGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSLVIDEIKRIIKDSEIMKEDDEKWPTKNGKQELEIRLGNDHISFTAKIGSINDVTDSADPEGLRVFYYLVQDLKLVFS-LIALHFKIK Orpsp11 --------VGHMGRFGHEFLEFELRYANNSNY--KNDS--MIRKEVSKSVMNELKRIVEESEIMKEDDKLWPLADGRQELEIVYGDEHISFTSKLGSLIDVQESEDPEGMRAFYYLIQDLKFVFS-LISSHFKIK Pench1 ENFYLRYYSGHSGRFGHEFLEFDVRYANNSNY--RNDS--LIRKEVSDALVEEVKRIIKDSEILKEDDSKWPQKNGRQELEIRIGNEHISFTAKIGSLVDVTESDDPEGLRVFYYLVQDLKLVFS-LISLHFKVL Phybl2 EEFYVRYYSGHKGRYGHEFLEFECRYANNSNY--RNDE--LIKKEISPAVLDELKRIISESKVMETDDSQWPTRNGSQELEVRLGNEHISFTSKLGSLAEVQDSKDPDGLRIFYYIVQDLKFVFS-LISLNFKIK Picst3 --------------------------------------------------------------------------------------------------------------------------------------- Plicr1 DPFYL--STGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVESSEITKEDDTNWPKKNGKQELEIRVGNDHIAFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Polpo DEFYLRYY-------------------------------------VSETVIDVLKKMITDSGVMMEDDKDWPEPDGKQEIEIVYNNEHISFTTKIGSLLEVEK-------------IQDLKLVFS-LIGLHFKY- Pucgr2 DPFYVRYYSGHMGRYGHEFLEFELRYANNSNY--RNDS--LIRKELSPLTISELKRIVAESEIIKEDDHNWPKKNGKQELEVRLSDTHISFTAKIGSLVDVQGSDDPEGLRVFYYLIQDLRFVFS-LISAHFKIK Punst1 DPFYLRYYTGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVKELKRIVESSEIVKEDDANWPKKNGKQELEIRLGNDHIAFTAKIGSLVDIQDSEDPEGLRVFYYLVQDLKLIFS-LISLHFKIK Rhior3 --------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 DPFYMRYYSGHVGSYGHEFIEFELRFALNTNY--RNEG--LLRRELSDATLKEFQRIVAESEITKEDDSKWPQKSGKQEFECRMAPYHLAFTAKIGSLVDVQNSDDPEGLRVFYYLVQDLKFVYS-LISLHFHIK Rozal11 TIFSIYKSVGHKGKFGHEFLEFELRYANMSNY--KKDT--MIRKEVAPSVISELRRIIEECEITKEDDSQWPQPDGKQELEIIMGDEHICF---------VN--------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------- Salro DEFYLRYYVGHKGKFGHEFLEFELRYANNSEY--KNDT--MIRKEVSPAVLGELKRIVEDSEIMKEDDNLWPAADGKQELEIVCGDDHISFTSKIGSMNDVNDSKDPEGLRTFYYLVQDLKFVIS-LIGLHFKIK Schco3 DPFYLR--TGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVSPLVVKEMKRIIESSEIVKEEDTNWPKKNGKQELEIRIGNDHISFTAKIGSLADIQDSEDPEGLRVFYYLIQDLRMIFS-LISLHFKIK Schpo1 SDFYVRYYSGHHGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSELVLKEVQRIVDDSEIIKESDESWPPENGKQELEIRMNGKHIMFTCKLGSLADVQNSDDPEGLKVFYYLIQDLKLCFS-LISLNFKLR Sorma EPFYLRYYSGHSGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSLVIDEIKRIIKDSEIMKEDDEKWPTKNGKQELEIRLGNDHISFTAKIGSINDVTDSADPEGLRVFYYLVQDLKLVFS-LIALHFKIK Sphar KDFYLRYYVGHKGKFGHEFLEFELRYANNSQYKQRNDSNDMIRKEVSETIVAELKRIVEDSDIIHEDDHLWPLADGTQELEVMMGDEHISFTSKIGSLTNVNESKDPEGLRAFYYLVQDLKLVIS-LIGLHFKIK Spipu1 E-LYVRYYVGHIGKFGHEFLEFELRYANSSNY--KNDT--LIRKEVSPSLIQELKRIVTDSEILKEDDKLWPVPDGRQELEIVMGKEHISFTAKIGSLVDVQESKDPEGLRVFYYLIQDLKLVFS-LISLHFKIK Sporo1 DPFYLRYYAGHVGSYGHEFLEFELRFALNSNY--RNEG--LIRRELSQATIDAIKSIAKNSEIVKEDDATWPKKNGKQELEVKLDNYHISFTAKIGSLVDVQNSSDPEGMRVFYYLVQDLKFVFS-LISLHFKIK Stehi1 DPFYLRYITGHSGKHGHEFLEFELRYANNSNY--RNDS--LIRKEVGPLVVQELKRIVESSEITKEDDTNWPKKSGKQELEIRVGNDHIAFTAKIGSLADIQDSEDPEGLRVFYYLVQDLRLIFS-LISLHFKIK Tapde11 TPFYLRYYSGHSGRFGHEFLEFDTRYANNSNY--RKDS--LIRKEVSKSMIEEIKRIVESSEILKEDDAKWPPKNGRQELEIRFGNQHISFVGKIGSLADVQESDDPEGLRVFYYLVQDLKLCFS-LVGLHFKLR Thetr --------------------------------------------------------------------------------------------------------------------------------------- Treme1 DPFYLR--TGHQGMHGHEFLEFEIRYANNSNY--RNDS--LIRKEVSPAVVDELKRIIRDSEITKEDDVSWPKKNGKQELEVRIDKEHISFTAKIGSLADVNESADAEGLRVFYYLVQDLKFIFS-LITLHFKIK Trire2 DQFYIRYYSGHMGRFGHEFLEFDARYANNSNY--RNDS--LIRKEVSSAVIDEIKRIVKQSEIIKEDDSKWPQKNGRQELEIRLGGDHISFTAKIGSLADVTESADPEGLRVFYYLVQDLKLVFS-LIALHFKIK Umbra1 DEFYVRYYSGHTGRYGHEFLEFECRYANNSQY--RNDS--LIRKELSPTMLKELKRIIEDSEIMKEDDNQWPRKNGRQELEIRFGNEHISFTAKLQSLGEVQESNDPDGLRAFYYLVQDLKLIFS-LISLHFKIK Ustma22 SDFYVRYYTGHQGRHGHEFLEFELRYANNSNY--RNDS--LIRKEISPLMVDELRRIVEESEIMREDDANWPKRNGRQELEVRLGKEHISFTAKIGSLVEVQDSEDPEGLRVMYYLVQDLKLIFS-LISLHFKIK Walse1 DNFYLRYYSGHSGKYGHEFLEFELRYANNSNY--RNDE--LIRKELNDLLALEIKKLIKESEIIKENDVNWPKRDGRQELEIRLEDEHISFTSKIGSLVDVQDSDDPQGLRVFYYLVGRRA-------------- Zygro1 --------------------------------------------------------------------------------------------------------------------------------------- [Cluster2669.fasta_al_trimmed; alignment length = 167] Allma1 MARPAARRKIKNPSLKVSR--RTQKKHFRLVAHPIVAEAWDNTKTVKANYEKIGLTAPG-------------QSATVHRDANGN-VT-------EPEFDKVLRQSASKTVKDLVALAQ-SSGELDWLHALVSKHG-DNY--TAMFKDKKLNVYQHTVPQLKSK-LKK Ashgo11 MASVRKRKMARSSVRKVTR--RNRDK-QRIACNPIIEKNWDYNLTLAQNYKRLGLTAGGEEIDD-SESDVE-GEARIQRDENGD-VVKVVYGTMDEDISELKQKVKTEVVQELESYASRSSREEEWLGRLYEKHG-EDY--NSMARDLKLNIYQQSVGDLKRR-MKK Aspfu1 MGRVLQKKKNRSSTPKQRP--KRTSG-KKVLGNAIIAQNWDRKLTLTQNYRRLGLVTGGSEKKK-DGR----GETRVERDETGK-IIRVIRDEENDPLNELSENAKSAVVQQLERQADQSKREEEWIMRLIERHG-ENY--SAMARDRKLNPMQQSEGDLKRR-IRK Aurde31 MANPRQRRK-RHGQAK-VK--SSRN-LKKIRGPKALQDAWDKEKTVRQNYAALGLVVTGLA-------AQAEGRGRILRDADGN-VIGVELPQE---------SQPNPVVEALEDLASKSRGEVSLMKDLQRTYG-SDF--DAMAKDRRRNVWQRTAGELRRS-MSK Batde5 MARPRVRRKIRNPSQKVSR--KQKNRM-DENAHPLVKDNWDKKKTLHQNYESMGLMAGGTGHE---------TLSKKTKPGKFS-V--------DQPELDLLDTSVNPIIATMQEEANNSSNEDLVYADLISKHG-LDY--EAMSKDLKLNRYQLTKGQLQRK-IRT Botbo1 MANPRQRRKARSSTYKAVS--QSRN-LKKIKGPKAIQDAWDRKKTLKQNYAALGLMSGGSE------VIGVEGKGRIIRDADGN-IVDIELGEP---------APKTEVVRELERLSTNSMHEVAWLRSLVALHG-TDI--EAMARDRKNNVWQKTPGELRKA-ITK Botci1 MGRELQKKKNRSGNNKIKH--KPK---SKPLGNAIIAANWRQDETLTQNYRRLGLTTGGIEKKS-ESK----TEARVERDETGK-IIRVIHDEKNDPLNSDDEASKNEIVKMLEEQASRSEREKEWIEKLVKRWG-ENY--GAMVRDRRLNPMQQTESDIRRR-VQK Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MTSVRKRKMARSSVKKNTR--RTKDK-QRIHSNPIIEANWDKSLTLKQNYKRLGLRAGGDERKQ-AKREKNQGEARLIRDPETNEVIKVIYGTMDESEEEIEN----SVIKQLEEYAEKSERENDWIKSLYEKYG-DDY--DKMKWDKKLNIYQQSAGDLKRR-IIK Cangl MTSVRKRKMNRSSVKKVSR--RNKDK-QKIACNPIIAKNWDYSLTLAQNYEKLGLKAGGQEAKS-DSDSEEDGEARIIRDAEGN-VVKVVYGKKDDDIDTIKAKEETEVVKQLEAFASRSPREVEWLEKLYKKHG-DNY--KAMFFDRKLNIYQQSEGEIKRK-MRK Capow --MGRQSSKRKKHTVRAAV-SSSKTARNLSVLHPDVQAAWDKNKTLKENFASLGLV-----------------------DAPGS--VDLLALDA---------PKVSEAVSALEAKAAKPPGVQEFVRALMERHG-TNY--KAMARDKELNYLQHTANQIRRK-CTL Catan2 MTRPSARKKVKNPRLKVTR--RTQDKHF-AVVHPVLAKVWDKKKTLAQNYEAIGLSSSGKGKVSSSSSSESSQAAKIKRDAKGN-VI-------DSAFDEVL-KPKTKTVQELIALAQ-SSGQLDWLHKLVQKYG-DDT--QKMARDRHLNVNQHTPAQLTRK-LKA Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MGRELQKKKNKSSIPKKRQ--KGP-S-KK-LQNPIIAKHWNQKETLSQNYRRLGLTTGGTEKTK-SSR----EEIEVERDETGA-ILRVVGTLENDPLVEIEDEPENPVIKQLEEAAMNSQREQEWVERLVNKYG-DDY--AKMARDLKLNPMQQTAADIRKR-VVK Coere1 MVRPIARKKLRNPKLKVSR--KSANK-ARYTGHPLLREHWDNSLTVSQNYRNLGLVSGGTVKN--AHQEKVDGYGLIERDEDGN-IVNVILADDDSDFE----PAKKEGARILEQYVAESVGERQLLQCYLDKHG-NDY--NAMFWDKQLNRQQLTKRQIQKK-IER Conco1 MANPRQRKKQKNPQMKAKK--MRQTK---IPNIDVIKNNWDKKLTLQQNYEKLGLATDGKGNNE--------GFGVVERDEQGN-ITKVTVAD---DDDFLDTPAKTDVVRELEKIASRSENQMKHAEKLIAKHG-SNY--EAMFRDMKLNTWQETVGQIRKK-CEA Conpu1 MANPRQRRKSKSSSYKPVN--HARM-QKKIRGPKILQDSWDKSKTVRQNYAALGLQSGGVE--GQSKVPEIEGFGRIVRDEDGN-VLRIEL-PEDEDDDALPE----SVVDALELLAKSSSGEKTYLDRLVDEYG-VDV--EKMARDRRLNPEQKTVGELRRA-LKK Copci MANPRQRRKARSSSYKPVS--HSKN-LKKIRGPKALQEAWDKKKTVRQNYARLGLVSGGSE--YEDGDAQMSGFGRIIRDESGN-VIGVEL-PQDQEMEALSEDKVVGLVDELESIAMKAPGEIAYMRRLFEKYG-DDV--ERMARDRKLNPDQRTAGQLRRA-LAQ Croqu1 MANPRQRRKSRSGNHRVRISKHANSRLKKQNFPAGLAAAYDRKQTPAQNYRRLGLLSGGIEKDDEDEDEVESGEGRIVRGADGN-ILKVILGDEEDPSSIVIVEPKTSFVAQLEQISVSSENQVKWIMKLVDKHGIDNV--NAMAKDIKLNTHQKTEGEIRHM-ISK CryneH991 MANPRQRNKAKSSTQKPSL--NAKQKLRKLKGPEVLQERWDKKKTVFQNYAALGLLGPSTS----------RGFGQIIRDEEGN-VIDIIIDED---------EAKTEVVKRLEELAASSMSERTWLQQLVDKYG-DDT--ERMARDPKLNVWQKTDGEIKRM-IKK Crypa2 MGRDLQKRKRRSSRPTIRQ--SNQ-P-KKPRGNSLIAKNWNKNETLSQNYRRLGLTTGGIEQH---------QSVKVERDADGN-IVRVLR---NDPLNDLE-SGETKVVDLLEQQANMSAREREWIERLLAKHG-DDT--AAMARDAKLNPMQQTAAEIKRK-IKT Debha1 MTSVRKRKMNRSSVRKNTR--RVKDK-KKIHSNPIIAANWDKSLTLQQNYKKLGLRAGGKEQDK-A--AD--GEARIIRDPETNEVTSVIYGTMAE--TEGES----SVIKQLEEYAQKSARENEWLEKLHEKHG-DDY--DKMMWDKKLNIYQQSAGDLRRR-ITK Dekbr2 MVSVRKRKMARSSVGKVSR--RKKDT-HKKFGNQIIAENWDNKLTLSQNYERLGLKTGGVEKNE-DEGDLVDGTAKLIKNDDGK-VVKVIYGTKEQDSNVIEITKDSSVVKALEKLAS-SEREIEWLRKLETKYG-DDY--EAMKWDRKLNPFQESTGKLRKR-F-- Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MATARQRRRTKNPNRKVTR--RVSDRQKNEN--PALREAWDKRLTLKQNFERLGLAAPLAQKP-------------LAKPEDPS-V--------SKPDT--------------ENEANRGSG---IVGD---SSK-DDY--VKMARDLKLNVYQLTANQIKKK-LAA Fomme1 MANPQQRRKARSSSHKPVK--QSRL-LKKIKGPKVLQDAWDKHKTVRQNYAALGLASGGHVITQNAEASSKEGFGRIIRDERGS-VMDVVLGEEDFEIES---ERAKDVLRALEVASMGSNAEIKYLSRLVQTYG-TNY--EGMARDRRTNVNQYSAGQLRRA-IER Fusgr1 MGRELQKKKARSGRQPVRQ--LNR-S-KKPRGNDAIAKSWNKKETLSQNYRRLGLVAGGTEKQ---------SEARVERDADGK-IIRIIGS--NDPLNDLDEEETTDVVKQLLEQAKQSAREIEWLEKLVAKYG-DDT--GAMSRDRKLNPMQQTSANIAKR-LRK Galma1 MANPRQRRKARSSSHRPVS--HSQN-LKKIRGPKALQDAWDKQKTVRQNYANLGLVHGGVE--RGSSVQPSQGFGRIIRDGTGN-VLGFELNEPDLEVNDVDDPKDEQLVKDLEQVSASSSGEMQYLQALVKKYG-DNV--DLMTRDLKLNPEQRTVGQLKRA-LRK Ganpr1 MTRPAKRRKVKNPSQKVTR-RRADAKRKGALVHPLISKNWQAGKTLEENYETLGLLTGGKFKKDVMGDAEREGFGGLAHEEMGGEVIGLVVGKK---------KKEPKVADELERVAKESEQEEQSLRSLIKKHG-DNF--DAMARDKKLNPFLFTAGQLRRK-CEK Gloin1 MARPRKQRKIRNPSLKVSR--KNANKHFKIKGNSIIAANWDKKATLRQNYHRMGLMSGGVE-----------EEGIIERDEKGN-VINVTIGRSE---EVFDTPAKTDIIKALEAQAASSNGEKQFIEELIQKYG-DDY--DAMFRDIKLNIYQHTAAQLRKK-CQR Hisca1 MGRILQKKKNRSGAPRVKQ--KSNNG-NKVLGNAIIAQNWDKKLTLTQNYRRLGLATGGAENKS-NGR----AEMRVERDATGK-ILRVIHPENEDPLNEVGDSTSSAVVQALERQAALSKREEEWLERLVAKHG-DNI--IAMVRDTRLNPMQQTEGDIKRR-LKK Klula1 MASVRKRKMAKSSVKKVSR--RNKDK-QKIKGNPIIAENWDYSLTLAQNYKKLGLKAGGEEADE-SEDEKDSGEARIKRDDDGN-IVKVYYGKRDMDVEELRREVKTEVVKKLEAYASRSQREDQWLEQLYKKHG-DNY--KKMFFDKKLNVYQQTENVLRRK-ILK Lacbi2 MANPRQRRKTRSSTHKAVS--HSRN-LKKIRGPKALQEAWDKKKTVKQNYTALGLISGGNE-------IEIPGFGKIIRDEAGN-VLHVELNDTSTEMKNI--EKGGQLLETLESLSCIAAGEVAYLQRLVKKYG-NDV--ERMAIDRKLNPDQRTAGQLKRA-LRN Lenti61 MANPRQRRKLRSGSHKPVQ--HSRL-LKKIRGPKLLQEAWDARKTVRQNYEALGLASGGTE--HGGDEKNCEGFGKIIRDAEGK-VVEVQLGDEEETMEEVPDGASTGVVQGLEQLSERSKGERGTLSQLVAKYG-EDV--EAMARDRKVNTDQRTAGELRRA-IRK Malgl1 MANPRQRRKMRSGYSGATK--SAKKRLKRVMGPDVLRENWDSKLTVRQNYAKLGLLGGLDR----------NGMARVIRDDDGR-VVDIVEYED-------------------------QGRDSDTVQHLISVHG-SDV--HAMARDKRRNVWQKTPGEIRRA-YVL Mellp23 MANPRQRRKARSSNHKVRVAKHVNSRLKKLNFPAGLAELYNRRQTPTQNYRRLGLLS-------EDEDE---GEGRIIRDADGK-IIKVILGGDEDPSSIVI------------QISTTSDNQVAWIVKMIEKHGVNNV--SAMAKDLKLNTYQKTEGEIRHM-ISR Mnele TVRGKQRNKRRG-TIR-KT-NYGKEYNKKVITNDIVRANWDKNKTVKENFSGLGLV---------------------------E--VEF-----------------TEVVKKLEEQSKDSPAESELWDGLVRDHG-SDY--KAMARDKR-NTHQHTPKQIKRK-IES Monbr MGNPRQKRKLRAGVKKQTA--RQAERQRTQIQNSTIARAWDPKKSLLDNFRELGLV------------------AHRQKLGGGI-T-----------------REPTEVVRELEQRAASARGEIIFIQSCIQKHG-LDY--DAMAKDLKLNTYQHTANQLQRK-VNK Morel2 MPTVRKRRTIKTPSRKVTR--KTANKHKRVIGNKIIRDNWDKKATLRQNYARLGLLTGGIE-----------EQGIIQRDDAGN-IINVIVGKII--AEIMERKAKTDVVRALEAQAANSDGELVWAAKLVEKYG-DDY--EKMFWDRKLNPNQQTAKQIKKR-IAA Mucci2 MGTVRQKRAAKN-TNKNTR--RTADRHRKIHGNSIIKANWDKKLTLRQNYEKLGLLSGGRE--KPTAANNSTGEGLIQRDDDGN-VVRIIVGEQ----EILDAEAKTDVVRALEAQAANSEFETDWIQKLINKHG-EDY--KAMFWDKELNVYQQTAAQLKKK-CQK Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MGRELQKRKKRSSRAKVQT--HTI-K-KKPQGSGIVAKAWNKKETLSQNYSRFGLVAGGMAKK---------REVKVERDASGK-IVKVLR---NDPLNEIESSSRPEVVRMLEEEASRSERELEWLQRLVAKHG-DDV--AAMVRDIKLNPMQQTKGDITKR-LRK Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MGKVLQKKKARSGRSTARA--KDNSG-HKVLGNQIIADNWDRNLTLTQNYQRLGLMSGGRERLT-KDQ----GETRVERDETGR-ILRVIHDDDNDPLNDILA-ADSVIVQQLERQADQSTREGEWAQRLIEKHG-DNF--TAMARDRKLNPMQQSEGDLRRR-INK Phybl2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 MTSVRKRKMNRSSIKKATR--RLKDR-QRIHSNPIIAANWDKSLTLQQNYKRLGLRAGGQEQKR-AKREK--GEARLIRDEDTNEVVRVIYGTMSEA-SEVEN----LVIKQLEEYAQKSDRENEWLKSLYEKHG-DDY--DKMKWDKKLNVQQQSAGELRRR-ITK Plicr1 MANPRQRRKARSSSHKAVS--HSRN-LKKIRGPKILQDAWDKHKTVRQNYAALGLVSGGVE-------IDLGGHGRIVRDEAGN-VVGVEL-AEDDEMR---DEDVVKALEHLS-----SGGEVSYLSRLVSKHG-DDV--EAMARNRRLNPEQKTAGELRRA-IRK Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 MANPRQRRKSRSGAPKARLSKFANSKLKKRNFPGPLSNAYNPRQTPRQNYERLGLLAGGIEKKEEDENDDEEGEGRIIRDADGK-IIKVIIGDEEDPSKIVIEPPKTKFVEELEKISSNSENQTNWLLKLIEKHGLENT--HLMARDLKLNKDQKTEGEIRHL-ISK Punst1 MANPRQRRKARSSSHKPVS--HSRL-LKKIRGPKVLQEAWDPRKTVKQNYAALGLMSGGMEVDAGTET----GFGRIVRDAAGR-VVDVELGEE----EEV--GSGNEVVQALAQMTSESSGEVGYLRRLVQAHG-RNV--AAMARDRRLNTDQRTEGQLQRA-ISR Rhior3 MATPRQKRARRS-TNKNTR--RVADRHRKITGNAIIKANWDKKLTLRQNYAKLGLLTGGSE-----ESVAEQGEGIIQRDDEGN-VVRVIVGEA----EILDAEAKTDVVRQLEEQAANSGFETHWIQKLIDKHG-DDY--KAMFWDKELNVNQHTAAQLKKK-CEK Rhoto1 MVNPRQRRKARSGIAKA-S--ASKN--QKIKGPELLVKGWDRKKTVRQNYAALGLLAGGLEADSLEDDTEMDGMARIIRDEKGN-VVKIIVGGEDEEEEEKQPEAKTDIVRALEERASHSEFEHDWLVSLVAKYD-EDI--GKMARDRKANVWQKTPGELKRM-IAK Rozal11 MTRPCRRRKVKNPRSVVSR--RVQNKHY-IIHNAIVREDWNHDQTLLENYKQIGLR--G-------------QGQLVDK---------------EP----------TPVVKKLEEKAERSLQEIEFIKSMIKKHG-GDFKIKAMEKDKKLNVWQNTARQLEKK-VTR Sacce1 MTSVRKRKMNRSSVGKATR--RNKDK-QRIQSNPIIAANWDYSLTMAQNYKKLGLRAGGKEADE-DEDEGEDGGARIQRDKNGD-VVRVVYGKKDEDVNEIKATEETEVVKKLEELASRSEREEEWLEKLYKKHG-DDY--KKMFFDKKLNIYQQSEGDLKRR-LLR Salro MANPRQKRKLRSGYRKQSR--QQAKKQR-EIVNEAIAKVWNKHKSTKHNLAAIGLV----------------------RKPETK-I-----------------ELNMDLVKKLEEQAAASRGEVVFIQNCLQKHG-TNF--QAMSLDLDLNKQQHTPAQLRRK-VLK Schco3 MANPRQRRKARSSSHKTVS--HSRNHFNKIRGPKALQDAWDSRKTVKQNYAALGLASGGTE--QQSTPESVEGHGRIIRDEAGN-IIRVELAPEDLDMEQL-EGKGKTVVKELERIATSSEREKVYLQRLLEKHG-KDV--DSMARDRKLNTDQRTAGELRRA-LRR Schpo1 MANPRQRNKQRSGKPRLTR--RNANK-KAIYGNFVIQQNWDKHATLRQNYARLGLLTGGVE--K--------GQAIVRRDDDGN-IIEIIHGEA----DVLDKPAKTEVVRQLEEEAVKSAFEHAYIQRLINKYGTEDF--ESMAKDVKLNSKLFNGSKLKN----L Sorma MGRELQKRKKRSSRATVQT--HTI-K-KKPQGSGIVAKAWNKKETLSQNYSRFGLVAGGMAKK---------REVKVERDASGK-IVKILR---NDPLNEIESSSRPEVIRMLEEEASRSERELEWLQKLVAKHG-DDV--AAMVRDIKLNPMQQTKGDISKR-LKK Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 MARPRVRRSTKNPSVKVSR--KQKNPY-NAGAHPLVRKNWDKNLTLKQNYERMGLIAGGTEHE--------------AKPEQDS-A--------NGP------SAKSAVVEAMEAEARDSEQEGKVFGDLMRKHG-RDY--EAMSRDIKLNRYQLSAGQLRKR-IER Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 MANPRQRRKTRSSSYKPVK--HSSL-LKKIRGPKVLQDAWDSKKTVRQNYTALGLASGGVE--EGHDITTPEGHARIIRDSDGN-VVGIEEAEASDSDQLIEDETTVETVSSLPRPNP-SSSERTYLERLVSKYG-QDV--DAMARDRKLNPTQFTAGQLGRA-IRK Tapde11 MANPRQRQKQRTSRGKLTK--RTGDK-LKIKGNAIIAANWDKTQTLQQNYKRLGLVSGGVE-----------NEAIIKRDADGN-VAEIIYS------SVAAKPETTDVVKALEQRALESQGELEWLRRIIAKHG-GNY--EKAARDFKLNPMQQTAANIKKRAIKA Thetr MGNDASAVPGPESTTQVSR--RNK---RKFVNNAIVRSKWDSDKTVTENYKNLGLVSKADRKK-----------------QPGQKL---------------------NIVAELEKQAKRSAQQFRDMHAFVKKHG-DDV--AKMARDMRLNRWQKTATQLAKS-LAI Treme1 MANPRQRNKARSSTHKPSL--NQKQAKRKLKGPLVLQEGWDKTKTVFQNYAALGLLNVSRS----------HGFGRIVRDEEGN-VVDIIIDED------------TKLMKELQRIASTSTSEHAWLSSLVAKHG-EDY--TAMSKD-KENVWQKTPGELKRM-VKK Trire2 MGRELQKKKRRSGRPAVRQ--SNR-T-KKPRGNSVIAKNWDKNETLAQNYRRLGLLTGGTEKKS-SSSSSAPSEAKVERDAAGN-IVRVLGR--NDPLNELDSVGTTEVVKSLIEEAKNSERETEWLESLVAKYG-DDT--RAMARDMKLNPMQQTAADIAKR-LKK Umbra1 MANPRQRKMNRS-GNRVTR--RTANKHKKITGNDIIKANWDKKKTLRQNYEKLGLLTGGKEIL------EAEGEGFIQRDDEGN-VVRIIVGDR----EILEEEAKTDVVRALEEQAANTQFESDWVAQLIAKHG-DDY--EAMFWDKKLNEYQQTAAQLKKK-CQK Ustma22 MANPRQRRKARSGTLKPSL--NAKKKLARIHGADVLKDNYDPKLTLRQNYARLGLVNTGGT----------EGMARVIRDDAGN-IVDII-------------ASNPDALQQLEQIASQSQKESQWLVELVKKHD-DDT--QAMAKDRHLNLWQKTEGEIKRA-IRK Walse1 MAKPRQRSKQKSGSYRPTKTTSNKTTLKN-----ELARQWDKSKTLRENYARLGLAVGGVEKEQQKEDRSDD-MGRIVRDDEGN-VVDVIIDEP---------SSNTDVVKLLEAKAATSADEWKWLIKIVKTHG-RDL--EEASRDLKINTWQKTKGELSRA-VKR Zygro1 MTSVRRRKMNKSSVGKATR--RNKDR-QRIASNPIIAANWDYNLTLKQNYKRLGLTAGGEEADS-DEDDEDKGEARIKRDENGN-VLEVIYGQKSEDEQQNENSAKTEVVRQLEEIANASAREEEWLERLYNKHG-DNY--RKMFFDNKLNIYQQSEGDLRKR-IRA [Cluster2671.fasta_al_trimmed; alignment length = 131] Allma1 ----------------------------------------------------------------------------------------------------------------------------------- Ashgo11 M-LTTTIPLYISLFRNVSNAPEIVDSLAELPYSIIDARTLLSREQLLSAVYRAMRTRNLHTEVLLCLSPTSNIGDAMKRFGIKKDSTSVVLVKADETFDPKGFEELEF-SDIRENYKL-AALVHAIQLRGL Aspfu1 L-ETIRLPVHIALYRDVNNSPFLRQQLL--EYAFIDASMVFSRSHILSAIFRAVKSRNVHSEIVFSLSPANNIADSFRKFGITDSTTDLLVVKVTHASVATHLSPVPF-ADIKKAYKLGLSLIGAIALRGA Aurde31 M-ETWQYPVHLALFERVQNAKALRARLISANFAFIDASLVASDLHLQTALLYALRTKTIHSEILWALNPTNNISEAIRRFGVSDSSQRLIVLRVSAGPVEASMTIVPL--SLKKYYKLP-IITSTVATKAV Batde5 I-PQLILPVHAYLFTNVIDTQQLLTHLRHVTAVYLDASKIFSLFQLSLAVTKTHRTHSDQSEILLSLSGDTSISQAFKQFGISKHTCNVLVVDYHNQEILQDLHIAEF-TDIRKVG--------------- Botbo1 L-EHLWYAVYIALFANVANAAAIRNRIVAANFAFLDARPITSRLHISTAIYQALRTKTVHSEILWTLNPSNNISESIKRFGISSTSTSLLVVHVAPAEVAQRLDMVDL--DVKKYYKLQELVVSAVAMKCV Botci1 LLQSIPLELHIALYRNLTNASFLHQQLL--EYAFIDASV----------------SRNIHSEIVFSLSMNNNIAESFRRFGITPSTTSLLVVKVSASQISEHLEPVPF-DDVKKLYKLNIMVLGAMALRGA Caeel L-YELQPDCRVCLFKDVKNAAELSQQLKEGDAALIRAELVLEPFVLLAAANRAVSCRSLAAELVYSLSPSRNITDSLVTFGIAEHSTAIIAAIFDSGKAMKKLTPVPL---IKKVYQVG--IVSRMVSKDF Canalb1 TSEVIKFPIHISLFINVENITTIKSNLISADYCFLNTKYIISKEHLFQSIYKSLSTRNLKSEIIYNLSPINNVGDALKRFGISEDCPNCIVIKIDLKE-----ELIEL-NDFRKLYKLNRLAIGACILRGY Cangl --MNFKIPISITAFENVTNSESIRSKVATLPYAFLDARMIYSQEQLYAALYRVLRTKTIHSEIMLCLSPTSNIGDAFKKFGIKEDSSTVICLHIDEPELPSLSQEISL-SKVGHVYKINSMIVNMIQLRGL Capow ----------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------------------------------------------------------------------------------------------------------------------- Cioin M-ETY--DVSVAFYRNVKNAKELKELAM--QASFVKASMIADVLQIKAAAAKGFKTKTLHSEMIFNLSPSNKISDCFQLFGLKDTSTDVVAVTLENE----KVDLVSV---IKKLYKITDCILSQMAAKDI CocheC53 V-RTFQLPIHVALFKDVANASHLRRQLL--DYAFLDASMIVSPQHLLSATFIALKTRTPHSELVFRLSPNNNIGESYKKFGISDASTQIIAVKLTNQTVSAHLSSIEI-ADVCKVYKLASLVLGAMALKGS Coere1 ----------------------------------------------------------------------------------------------------------------------------------- Conco1 M-NNFVINLF---YKNVKNPDQVLKKLISGSYCVLKAKNILSLFQLQLAIYFTIKTKSLEAEIIYSLAPHTKISQAFQEFGIDTKGQDLYVIHLSTEVLKEDLSEIPF--DIAKIYGFDKSV--------- Conpu1 M-ETIHQPVHVALFIDVFNAAALKARIVRANFAFVDASLITSALHLQTAISQASRTKTVHSEILWALCPTNNISEAIRRYGISDTSKALFVVRVG--DVEERMRVVPL--SVKKYNKLNNIVISSVASKGV Copci M-DGFTFPAQFALFRQVENAAQLRKRIIEANFAFIEAKLITSRLHLQTAIHQAIKTKYVHSEILFALNPTNNITEAIRRYGISDTTTDMIVVRVPPSNAQELMHIVPF--SIKKYYKLNKIVVSTVAMKSV Croqu1 M-ERFEIPVYLWFFTQLGNAAELRSSLIEADWAFLNSSMITSLQHLQTAIYQALKTKTIHSEIMWTLSPGTNISDAIKRFGMDPKATSVVLVKIQASNLNDAAKLVPI--DIRKVYKLNHLVISTVALKTV CryneH991 M-ETYAYPIHIALFKNVTNAPQIRKRLIEADFGFVEANLLVSKEHLLIAILSTLRSHNLHSELLLLLSPNNNITDSIRRHGVSDSTTNLAVVKFKVEEVYEAMELTGW--EVDKIYKLN--VVSTVAVKNV Crypa2 L-EAVSLEVHVALFRNVSNAGFLQSQLL--EYAFIDATTIVSRFHVLSATYKALRSPNVHAETVIALSVSNNISEAYRRYGISPEVQDMIVVKVTAEQVWQHLTAVPF-TDVNKYYKLNMLIVSAMALRGV Debha1 VYEELKLAVLIFLFTGVPVLKQVKEQLISGDFCFLNPQHIISLEHLYSSIHKAVRAKTLNTEIIFNLSPINNIMDALKRFGVDEACPNLITIKVDLNDHLLKIHNPRL-NNLKKVYKLNRLAIGACQLRGC Dekbr2 --------IFASLYKGVH--REIRK-LIASDFAFLNADNVICLEQLYSALFRCFKARSIHTEIISDMSPLRNIMEALSKFGIPSKTSNMIVLKVGLDN----LGGLYV-TDIIKNYKLGRLVVDTIQLRGL Dicdi M-KQYPIKLTILLFKNVTNTNEIKDGLQNGDWSVANCKPIFDDQQILIA-----ATKSISA-----------FSESKK---------------------------------I------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------- Fomme1 M-ESYTYKVHVALFTNVQNAAELRARIVNASFAFIEAKLVTSRLALQTAVYQSMKTKTVHSEIIWCLNPTNNITEALRRFGVSDNSSSLLVVRVS--DVEKQMDLVHL--DIRKYYKLNELVTSFVAMKSV Fusgr1 L-ETVTLEVYVALFRGVKNAAFLHQQLL--EYAFIDASVVVSRLQLLSAVFKATRTPNVHSEIVCTMSSSNNIADAYRRYGISPSTQDLVVVKVTQDQIWEHLEAVSI-TDVRKYYKLNSLVIGAMALRGV Galma1 M-ESLLFPVYIALFRNVSNAAALKSRIVAANFAFIDARLITSKIHLETAIYQAIRTRTVHSEVLYNLNPTHNITEAIRRYGVSETNTDVFVIRIDASTVQEKMNIVPI--SIKKYYKLNNIVVSSVAMKSV Ganpr1 MPTTFALPAHVWLFGNVAHQKTIRQAIIKGESAIVDARMIVDVSQLLLAATRALKTRTVYSEIIFNLSPGTNISESLRTFGVRDDSTALLALVLPPDDLTPRFSPSPT---VRSTFRLVGEVVNAMALKGH Gloin1 M-QSFTLEIHILLYKNVSNAAELRKRLL--SYAFIDAKMVLDKFQLLVATNDAVKTHNVHSEIVYSLSPTTNISESLRRFGISDSSTSIVVVKVNSEEARSHLEECDI--KIKKVINFN------------ Hisca1 I-QTIQLSVHIALYRDLQNASFLREQLL--EYASIDAATILSTTHLLAAVFRALKSKNVHSEIVYSLGANNNIAESFRKFGLTDATKDLIVVKVTNESVAQHLIPLTF-DDIKKAYKLGRTILGLMALRGS Klula1 V-LKYKIPIHVQKYNNVTNSSELRSKLAELPFAYIDSKTVISVEQLSSAIYKAIRTRTIHSECILSLSPSSNIGDALNRFGIKEGTTDIIVIKIDSNEEPYDGDLVPV-SDIKTV---------CIPCDKL Lacbi2 M-DFFHFPAHFALFRDVKNSQSLRKRIIAANFAFIDARLITGRLHLQTAISQAIRTKSVHSEILWALNPTNNITEALRRYGVSDTTTDLIVVRVDSAKIQELMKIVPF--AIKKYHKLNNIVISTVAMKTV Lenti61 M-QSFHYPVHVALYTNVTNSAEIRGRIVRANFAFLDARLICSPLHLQTAVYQAIRTKTVHSEILWALNPTNNITEAIRRYGVADTTTALIVVRIN--DVEKRMTLSSL--DVKKYCKLNEIVTSSVAMKSV Malgl1 M-ETIYLPVYIAQFDHVKNGSELRHALVQADMAFVDARLVCSRQQLITAILQAIKTPSIHSDILWTLNPNNNIGDALRRFGVSAATSSLLLVHVQPQAVAQQMIALSM--DVGKTYKIQACICSMVASKYV Mellp23 M-EHFDIPVYIWFFNKVTNLTQIRSSLIEADWCFLNPKMITSSQHLNTAIYQALKTKTIYSEIMWTLSPGTNITDSIKKFGIDPKSDKLILIKIESIKLNQLASLISI--NVCKVYKLNRIVTSTVAFKSV Mnele M-TRLNLEVEYMIFRNVRNISELTTLLKSGSSVLLSENMVVSPLHLAVAVNRALKTKSINTEIILCLSPNNNISQSLTRFGLNANSYNVISLSVSLSEKVQDLDLV---NDVYDVYGVSNSVVTKIATKV- Monbr LSLSLSLSVCIGLFEHVKNASDLRARLMAGEAACLSPACLVSVHQLRLAILSAYKTKTVQAEMMYALIPNKQLKQAFASFGIEDDATTMVVVVLGDATKWASV------QDVRKV---------------- Morel2 M-ESFPIDIHMACFTAVKNAPDLKEKLQ--TFAIVESNLIMDVFQLLLAATKAAATQTISSEIIYNLSPSKNIAESLKRFGITEDTTSLIAVKINPDEIMEEMNLVSF--SLRQYYKI-NWIIGAIAMKNV Mucci2 M-ETCTLEVHIALFRNVTNAPELRQRLI--ACSLINAKLVINKLHVLLAANRAVKTHNVHSEILYDFGTTNNIAKTFITFGIADDTADVVAVKISEADAEMHMNLVSL--DIESTYQLGSLVAGGMALRGH Mydma Q-QSYKVDIQVALCNNVTNTSYLREKCL--NCAILSTALIPDIFPVLISCNKSVKTRNIHTEIMLNLSSSNSIKDSLKLFGANDTDSKLLFVMVEEQDKFCEINFVVV---TKKHYKISNAISMRIASKDV Neucr2 L-ETLQIEVYAALFRDVQNVDFLQAQLI--EYAFIDASVIISRTHLFAAIFRALQTPNVHSDIVIGLSPTNNISESYRRYGLTPSTRDVLVIKITPESIWQHLTPVPL-TNVRKYYKLNGLVISGIALRGL Orpsp11 M-KQFEL-AYISLYNNLKNQKELQEMIINNNCAVINAHM-------------------------------------------------------------------------------------------- Pench1 L-ETISLSVHVALYRNIQNAAFLKGQLL--EYAFIDASMVLSRAHATAAVFRAVKSRNVHSEIVFSLNPTNNIAESFRRFGITDSTKDLLVVKVTHESVAAHLTPVLF-DDIKKAYKLGNSLLSAIALRGS Phybl2 M-ESYKLEAHVCLFRNVTNAPELRQRLI--ACALVNAELVINPFHVMLAANRAAKTHNINSEIVFDFSSTIHISQSLKRFGIEDTTTDIIAVKLTSEEAIAFMDVVAL--DIQKYYQTGQLVAGAMALKGL Picst3 SWTSVSFPVFISLFTGIDTISTVKKELIAADFCFLNTYHVVSVEHLYGSIHRSIKARTVNTEIIFNLSPINKIMEALKKFGVDEKCPNIIAIKVDTNNHLLKLSNIEL-NDVIKVYKLSRLVVAACLLRGL Plicr1 M-QTHRYPVHVALFTDVTNASSLRQRIVNANFAFIDARLITSPLHLRTAVYQALRTKTVHSEILWALNPSNNISEAIRRFGVSDATTALLVVRVT--DVDQKMTLSPL--TIKKHYKLNRIVVSSVAMKSV Polpo M-RQYEIN-----FNNVTNTQEIMDILLKGEWSIVNARIVYDDRHLLTAATQAISTNNIHTELIYRMSPTTNIRDSIKTFGLNIE---FYIVLF--ERI-DRVEES----DARKLYRLPKDILNSMAIKGH Pucgr2 M-ERLELPMNVWLFEQVKNTAEIKKALIQADWAFIDASMITSRQHLTTAVCQALKTKTLHSEILWTLSPGTNIMEAIKKFGLGPQTNALLLVKLEA--LDQAATLVKL-DDLRKIYKLNQLATATVALKSV Punst1 -----MYPVHVALFVDVRNAAEVRARIVKANFAFVDARLITSVLHLRTAIYQAVRTKTVHSEILWILNPSNNITEAIRRYGVGDDSRALLVVRVSAPDVEAKMDLVSL--DVKKYHKMGNIATTSVAMKSV Rhior3 ----------MALFENVTNASELKHRLI--TCALIDASFVIDRFHALLATNRAVKTYNLYSQIIFNFSPNTNIAKSFQQFGIKENTTSVVAIKVSADEAESFMNLVSL--DIKKAYQI-SIVAGAMALKGH Rhoto1 M-ESYPLPVHIAVW-SVRNAAQLRHRLVAADFAFVDAKMLTSRLHLLTAVQQAVKTKTLHSEVLWMLEPGNNISDSLKHFGLSPSTSHLALVHIANGEVLRRMELRSL--DLRKVYKLTRLVTSTVALKVA Rozal11 ----------------------------------------------------------------------------------------------------------------------------------- Sacce1 M-VVSIIPVSLALFEQVKNAKEIRSKMSELSFAFIDPRLVCSGEQMYSAIYKTLRTRNLNSECVLCLSPTSNISDAFLKFGIKDDSSQLICLKFDKEQLRTIMQEIEF-NDIRKIYKLSRALVDAIQLRGV Salro A-ERVVVEVLATVVRGVKNMGEVLKGVRSGQACFIKASMVPDLFVAAVAARHALTTRNVNTEILYSLYPGRQITTAFATLGPAETDTDVLVMVLKDDSQLSQVTVAPV---IAKLYGIK--VVTKMALKGL Schco3 M-ESFTLAVYTALYTNVTNSAEIRKRIVAADFAFVDARLVTSRLHLRTAIHQAVRTKTVHSEILFMLNPTNNISEAIRRYGVSDGSTSLLVVRVGEETVRTAAERRSV--DVKKYHKLNNIVTSTVAAKTV Schpo1 ----MILPVHVFVYENVSNCAAIHEQLI--DYAFLDAATILYKKQVYSAIIRALKTKTIHSEVILSLSPKTEISSAFRQFSMTKKSKNIVVVKITEEEEFERLNRVEF-SDLKKNYKLDASILSSIALRGY Sorma L-ETLQIEVYAALFRHVQNVDFLQAQLI--EYAFIDASVLISRTHLFAAIFRALQTPNVHSDIVIGLSPTNNISESYRRYGLTPSTRDVLVIKITPESIWQHLTPTPL-TDVRKYYKLNGLVVSGIALRGL Sphar TTETLSLGLHV-LCVDVQNVDELLEKSKARPYALIDARIVVSPLQLYTAATCALKTRRLHSEIVFCMSPSGNVNDSLIKCGITPDTTAFVLMAVADEKAYNALLVVSA---INSVYKLDGMVVSKIACQDM Spipu1 LPPLFTPPIHVTLFRNIRNAVDVRNLVIKGECVLINAATIVDVFQIQMACTKALRTRSLYSEILFNLSPTNNISDAIRQFGISDTTTA-VAVVMPPEEVRLRLEPIPL---INRIY---ALVVGAMALKGH Sporo1 ----------------------------------------------------------------------------------------------------------------------------------- Stehi1 M-ETFTYPVHVALFLDVSNAKDLRTRIVNANFAFIDARLITSRLHLQTAIYQALRTKTVHSEIIWALNPSNNITEALRRHGVSDGSTSLFVVRVQ--DVQSKMAISPL--SIRKYYKLNKIVVSSVAMKSV Tapde11 M--ECTLPISIQLFSNVTNAATILAAIK--NFCFLDVRRICCLEQLLYAVMRAMRTKTVYSEIVYSLSPNQNITEALQRFGVAGDSRALVCIAID--------ESEEV-TNLKSTYKIDAQIISSIALRGN Thetr L-EVVQLESAV-RFVEVTNAASIRKEAMSGQLAVLDGSLVIGPTQLAIATMRALITHTVHSEIIYGLSPSSSISAAFKNHGVSKKSKSLVLVWVDA-EAMKEVTMVPVGADVARVYDIGRLVLEKMALRDA Treme1 ------MPIHLALLRNVTNSPEIRRRLIEADFAFLEASMLVSRQHLLIAILNTLSTHNLHSELLLHLSPNNNITDSLRHHGISDHTATLLVVRLS-EEIWDKIQLVSL--DVDKVSSCS------------ Trire2 F-EIVQLEIHLALFRNVKNAGFLHQQLL--EYAFIDASTIVSRVHLLSAVFKAVRTPNVHSEIVVSLSSSSNIADAYRRFGVSPSTSDLFVVKVSADSISQHLDAVPA-TNVRKSYKLNRLILGGMALRGV Umbra1 M-ESFQLEIYISLFKNVKNAVELRQRLL--AWALVNASLVVNTFQILLAINKAIKTHKINSEIVYDFSSTNNISQSLRRYGVSDDSTALIAIAINPGDIEKAMELVPL--SIRKYYQLNPLIAGAMALKEI Ustma22 M-ESISLPVHLAHFSNLTQSAAIIDRIISADFAFLDPTKLCSKLHLLSAVTQAAKSKTPHSEVIYMLNPGNNVGESLKRFGLSPTSSSLLLVKFDKQAILQSMTPIDI--DLNKIYKLQDIICTSVAMKLV Walse1 ----------------------------------------------------------------------------------------------------------------------------------- Zygro1 A-LISSLPISLRLFHNVSNASEIRSKVAQLPYAIIDARSICSLEQVYSAIYRALKTKSLHSECLYSLSATSNIGEAYKNFGIKDDSQMLLVIQIDKDQQDLQLDEVPL-NDIRKIYKL-RAVVNCIQLRGL [Cluster2677.fasta_al_trimmed; alignment length = 139] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 RGVNPATLFEKAVRDRITDSYYWKEQCFGLNAATLCD-RAVE-LTSIGGTYKPTPFLCLAFKLLQLNPEREIILEYLFKYLRALAAFYVRLTDVYKTLEPLLLDYRKLKRRLTYMDQFVDDLLTKDRVCGTSLWKLPAR Aurde31 HGQNPQSLVEYTIRLRIYEADFWKEHCFALTAETLID-KTIE-LQYIGGVYRPTHFLCLLLKLLQIQPEKEILVEYLFKYLRALAAMYIRMTEVYELLEPLLKDYRKLRVRLTYFDAFVDDLLHEERVCDIILPRIPKR Batde5 HGTNPQFLIEKILRERIYESAYWKEKLFGVSAETLLD-RAVE-LQAIGGQFKPTEFICLALKILQLQPDDEIITLFLFKYLTALAAFYIRLTQVYRRLEPLLQDRRKLRRRLTFMDQFISDLLLEDRMCDTILPRLTKR Botbo1 HGTNPQFLIEKVIRSRIYESPFWKEHCFALTAESLID-KAIE-LNSIGGVYKPTQFMCLLLKLLQIQPEKEILVEYLFKYLRALAAMYIRMTEVFQLLEPLLTDFRKLRERLTYMDEFVYALLTEERVCDTILPRITKR Botci1 NGLNPATVLEKPVRERIVDCYFWKDQCFALNEADIVS-RVVSHVTFIAGTYRPSPFLCLAFKLLQLGPGDDILKEYMFKYLRALALFYWRMTDVYTMLEGYLEDRRKLRRKLTFMDQFVDDLLTKDRVCGTTLWKMPKR Caeel KGTNPQFLVEKIIRQRIYDSMYWKEHCFALTAELVVD-KGMD-LRYIGGIYKPTPFLCLALKMLQIQPDKDIVLEFIFKYIRALGAMYLRLTEIYKYLEPLYNDFRKLRYMAIYMDDFIDNLLREDRYCDIQLPRLQKR Canalb1 YTINKSNLIEPIIRHRIQDSLFYKQHLYLSNEATILP-IIIEHVHYIGGTDRPSTFISCLFRLLELEPSKEIIKTYLFKYLTALTLIYIRLTEVYSIFDQYFQDFRKLRIKITFIDEWVDTLLVNERVIDLMLPRLIPR Cangl ------------------------------------------------------------------------------------------------------------------------------------------- Capow HGTNPQYLIEKILRERIVEDAYWKEHCFALTAESVID-KAVE-LAYVGGTFKPSPFLCLTLKLLQLQPSHDIIMTYIFKYLRALGAFYLRLTEIYEVLEPLYTDFRKLRTRLTHMDEFIDRMLRDDRVCDVALPRLMQR Catan2 ------------------------------------------------------------------------------------------------------------------------------------------- Cioin KGTNPQYLIEKIIRSRIYDSRYWKEQCFALTAELLVD-KAMD-LKYIGGVYKPCPFLCLILKMLQIQPDKDIIVEFIFKYVRCLGAFYMRITDCYKYLEPLLNDFRKIKFQITHMDEFIDELLREERSCDVILPRIQKR CocheC53 RGQNPALLFEKGVRERITESYYWKEQCFGLNAATLCD-RAAE-LKFIGGTTKPTPFLCLAFKMLQLVPDKEIVLEYLFKYLRCLAAFYIRLAEIYKTLEPLLTDYRKIKRRLTHVDQFIDDLLTKERICATSLWKLPSR Coere1 -----------------------------------MD-KAVD-LTCIGGCFKPTEFLCLTLKLLQLQPDRQMLDVLVFKYLRALALLYFRLTEIYQKLEPLYADYRKLRSKIVHIDEFVDSLLRENKVCFITLPGITKR Conco1 RGLDPQSLIENIIRQRIYESLYWKEFCFGLNAESLID-RAVD-LNCIGGQFKPENFLCLLLKLLQLQPQWDIILTYLFKYLRILAAFYIRLVQIYELLEPLLEDYEKLRIRLTHVDEFVDQLLTEERVCDTILPRIPKR Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------- Copci HGQNPQFLVETVIRNRIYDSSYWKEHCFALTAESIID-KAIE-VKYIGGVYRPTEFVCLLLKLLQIQPEKEILIEYLFKYLRALAALYIRMTEVYELLEPLLKDYRKLRQRLTFIDEFVYALLTEERVIDLILPRLPKR Croqu1 HGTNPQFLIDKVVRSRIYDSQYWKETCFALTAESVID-CAIR-LKYIGGTYRPTEFMCLTLKLLQLQPEKEIILEYLFKYLRALAVFYVRLTNVYQTLEPLLKDYRKLRYRLTTFDDFVDSLLIEDRVCEIVLPRLTMR CryneH991 HGSNPQYLIEKVIRARIYDSLYWKEHCFALT----------D-LRAIGGVTTPTPFICLVLKLLQLQPEKEILIEYLFKYLRALAAFYVRLTEVYEILEPLMKDYRKLRVVLTHFDEFIDELLTQERVCDIILPRLTQR Crypa2 NGLNPATIMEKAVRERIVDSYFFKEQCFAVNEADIVD-RVVDHVHFIGGTYRPTPFLCLAFKLLQLAPPDDVLREYLFKYLRALAIFYIRLTDVYTLLEPYLEDRRKLRRKLTYMDEFVDDLLVKDRVCGTSLWKMPSR Debha1 NVIRKAYLVEPIIRHRIQDSLFYKQYLYLTNEATILP-VITSQVKYIGSTNKPTPFVCCFLRLLELEPSRDIIEMCLFKYLTALIMLYIRVVDVITTLEPFYSDYRKLRFQLSHMDVWCDELLNNERVVDLILPRMVPR Dekbr2 HGVNPVLLIEKISRERILYSLYWQQPCVTLNLMTLLD-EVVFNVKLI-GTYRPTRFICIILRLLQIQPTSDII-AYLFKYLQAIAALYVRITDIYKNLEPLLSNYCRLRIYIIHMDEYIDNLLTGSSFCDLTFPRIVRR Dicdi HGVNPRNLIEKITRIKIQSHPYWKEKCIGLNEESLVD-RAMA-LESYGGCFQPTHFLCLLLKMLQIQPEMDIIKEFIFKYVRILGAIYLRLVDIYNQLDPLYKDFRALRRKKVFVDQFIEELLTTNYSCDIALPHIPSR Dmel HGTNPQYLIEKIIRSRIYDSKYWKEQCFALTAELLVD-KAME-LRFVGGVYKPTQFLCLTLKMLQIQPEKDIVVEFIFKYVRALGAFYLRLTDCYKYLEPLYIDNRKLRRQIVYMDEYIDELLRNDRVCDIILPRIQKR Enthi ----PERRLETILRNKIYNCEYWKQQCFTLTSETILD-EIVK-LHDFGGTYKPTKFIVLIMKLLMLRPDKSIIYEYIFKYVRVIGAFYLRLIECYQFIEPLYYDYRPLKYRIITIDQFAWNLLHLDYYCDITLPIITPR Falba HGTNPMNLIPKIMRERIFNSLYWKERCFGLNDADVVD-RAAE-ITHIGGTYTATPFICLALKLLR-SPNRETLIAFIFKYLRALGAFVFRLIDIYNYLEPLLIDLRKLRMRLSFLDSFVDELLTETHVLGVPMPTLVQR Fomme1 HGQNPQFLVETVIRNRIYECQYWKERCFALTAESLID-RAIE-LNSIGGVYNPTEFMCLLLKLLQIQPEKEILIEYLFKYLRALAAMYIRMTEVYEILEPLLKDYRKLRLRLTYMDEFADQLLHDERVCDIILPRIIKR Fusgr1 NGLNPATIMEKAVRDRIVDSIYYKMQCFACNEADIVD-RVVEDVKFIGGTYVPSPFLCLAFKLLELSPSDAVLLEYLFKYLRALACFYFRLTNVYEMLEPFLEDRRKLRRRLSYMDEFVDDLLTKERVCGTSLWKMPKR Galma1 HGQNPQFLVETVIRNRIYESTYWKEHCFALTAESLID-KAID-SRFIGGVYRPTEFLCLLLKLLQIQPEKEILVEYLFKYLRALAALYIRMTDVYELLEPLLKDYRKLRMRLVFMDEFICSLLTEERVCDIIMPRIAKR Ganpr1 HGTNPQYLVEKILRARIYESLFWKEHCFALTAETLID-KAVQ-LNAIGGHFKPTEFICLILKMLQIQPDRSICLEYLFKYLRALGAYYWRLTDVYKELEPLLEDFRKLRERITHMDEFIDALLREERVCDVQLPRLTKR Gloin1 HGTNPQYLIEKIMRTRIYESLYWKEFCFGLTAETLID-RAIE-LTSFGGEYKPTEFLCLTLKLLQLQPNKDIVMEFIYKYLRVLGAFYLRLVEIYQTLEPLLNDYRKLRKRIVCVDEFIEELLKEERVCDTILPRMLKR Hisca1 RGVNPATLFEKAVRDRITESYYWKEQCFGLNAATLCD-RAAE-LSYIGGTYKPTPFLCLAFKLLQLAPEKDIVLEYLFKYLRALAAFYIRLTDIYKSLEPLLTDYRKLKRRLTYIDQFVDDLLTKDRVCGTSLWKLPSR Klula1 ------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 HGQNPQFLVETVIRNRIYESTYWKEHCFALTAESLID-KALQ-VRFIGGVYRPTEFLCLLLKLLQIQPEKEILVEYLFKYLRALAALYIRMTEVYDLLEPQLKDYRKLRQRLTFMDEFVYALLVEERVCDIILPRLIKR Lenti61 HGQNPQYLVESVIRNRIYDSSYWKEHCFALTAETLID-KAIE-LKAIGGVYKPTEFLCLLLKLLQIQPEKEILLEYLFKYLRALATMYIRMTEVYEILEPLLKDYRKLRYQLTYMDEFVDQLLNEERVCDLILPRLTKR Malgl1 HGTNPQFLVERVIRSRIYDSTYWKQDCFALNAATLID-KAVD-LTYVGGTYRPSPFLCLILKLLQIQPERAIVLEYLFKYLRAVAALYVRLTEVYELLEPMLNDYRKLRWRLTHMDEFIDQLLTEERVCELILPRLTKR Mellp23 HGTNPQFLIDKVVRSRIYDSQYWKETCFALTAESIID-CAIS-LKYVGGTYRPTEFMCLALKLLQLQPEKEIILEYLFKYLRALAAFYVRLTNVYQTLEPLLTDFRKLRFRLVTFDDFVDSLLVEERVFEIVLPRLTMR Mnele KGTNPQYIIEKITRTRIYESKFWKEECFALTAELMVD-KAMD-LKYIGGTYKPTPFFCLILKMLQIQPEKDIIIEFIYKYVRCLGAFYLRLTDCYNYLEPLYNDYRKIKVKLSHVDEFIESLLTEESWIGQTLPRIQLR Monbr HGANPQFLVEKIIRTRIYDTLYWKEHCFALTAETVID-KAVQ-LDHIGGVYKPTPFLCLTLKLLQLAPDKDIIYAYIFKYLQALGVFYLRLVECYSYLEPFLEDFRKLRHMLMHMDEFVDQLLREDRVCDIILPRLMVR Morel2 HGTNPQFLIEKILRTRIYESTYWKESCFGLTESSIIE-KAYE-LTSIGGQYKPTEFICLVLKLLQLQPREEIVIKYINKYLRALGAFYLRLVDIYKNLEPLLVDGRKLRKRIIHMDEFIDELLREERVCDVVLPRLTKR Mucci2 HGRHPLHLIEKIIRERIQNSLYWKEKCYGLSAATLMD-RAFE-LEYIGGMYQPTEFLCLTLKLLTLLPEKDIIIELIVKYLRALGAFYLRLTEIYQYLEPLLNDYRKLRVRLTHMDSFIDDLLHKDRVCDIILPRLTSR Mydma ------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 NGLNPATIMEKAVRERIIDSYFYKEQCFGVNEADIVD-RVVEHVDFIGGVYKPSPFLCLAFKLLQLAPSDDILNEYLFKYLRALALFYIRLTDVYKTLEPFLEDRRKLRRKLTYMDVFVDDLLTKDRVCATSLWKMRKR Orpsp11 HGTNPQYLLEKIIRSRIYESLYWKEDCFGLTAESLID-KADQ-LTCIGGQYKPTEFLCLTLKLLQLQPEKEIIIDFISKYLRALGAFYFRLIEIYKYLEPLLYDFRKLRRRIIHMDEFIDSLLRDERVCDTILPRILKR Pench1 RGVNPATLFEKAVRDRITDSYYWKEQCFGLNAATLCD-RAVE-LTSIGGTYKPTPFLCLAFKLLQLGPDRDVILELLFKYLRALAAFYVRLTDVYKTLEPLLLDYRKLKRRLTYMDQFVDDLLTKDRVCGTSLWKLPPR Phybl2 HGRDPQHLIEKIIRERIYDSLYWKEHCFGLSAATLMD-KAVE-LSAVGGQYQPTEFLCLVLKMLQLQPEKDIVIELIFKYLRALGVFYLRLVEIYQYLEPLLNDYRKLRVRLSHMDVFVDQLLREERVCDVILPRLVAR Picst3 NVLNRAHLIEPIVRHRIQDSLFYKQHLHLTNEASILP-VIIDQVHYLAGMDRPSPFICCLLRLLELEPSMEIVQTCLFKYLTALMLIYIRLVLVYTTFDKYLSDFRKLRTKLTYFDEWIDNMLLQERVMDIILPRLTPR Plicr1 HGQNPQFLIETVIRSRIYECTYWKEHCFALTAETLID-KAIE-IHNIGGVYKPTEFICLLLKLLQIQPEKEILLEYLFKYLRALAAMYVRMTEVYEILEPLLKDYRKLRIRLTFMDEFVNELLTEERVCDTILPRLIKR Polpo HGKNPTSLVEKIVRIKIQSHPYWKEKCMGLNESTLVD-RAMS-LNSFGGTFQPTHFLCLMLKMLQIQPSMDIVVEFIFKY-----------------LEPLYNDYRTIRLQKLSMDEFVEELLTTNYSLDIALPHLPPR Pucgr2 HGTNPQFLIDKVLRSRIYESEYWKESCFGLTAESIIDKTVFE-LSYLGSTFRPTVFICLLLKLLQLQPEKEIILEYLFKYLRALAAFYVRLTNVYQTLEPLLQDYRKLRTRLMTFDELIDSLLTETIVFEVVLPRLTSR Punst1 ------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 HGRHPLHLVEKIIRERIQESIYWKEKCYGLTAATLTE-RAVD-VDYIGGMYQPTEFICLLLKLLQLLPEKEIIIEFVFKYLRALGAFYLRLTEIYQYLEPLLNDYRKLRARLTYMDVFVDDLLTKDRVCDIILPRIMAR Rhoto1 HGTNPQYLVPTVIRKRVYDTLYWKEHCFALNSATIID-RAVE-LKYIGGTYRPTEFMCLVLKLLQLQPEREIVLEYLFKYLRALAAFYVRLTNAYETLEPLLDDYRKLRFRILTMDEFVDQLLAGEMVCEIQLPRLTQR Rozal11 HGVDPQFLIEKITRTRIYESQYWKENCFGLNIETLVD-KAVK-LDHIGGLFIPTPFLCLVLKMLQLAPTKDIVFEFVYKYVRALGVFYLRLVEIYRELEPLLADYRKLRLRIIHMDEFVDELLTQERTFDTILPRIVKR Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------- Salro HGTNPQFIVDKIIRSRIYETLYWKEQCFALTAETVIE-KAVE-LTYVGGVYRPTPFLCLTLKLLQLQPDKDIIIEYIFKYLRALGAFYLRLVDCYRYIEPLLNDYRKLKRMLTHMDEFVDELLREDRVCDIGLPRIQKR Schco3 HGQNPQFLVETVIRNRIWESSYWKEHCFALTAESLID-KAIS-LRAIGGVYRPTEFLCLLLKLLQIQPEKEILVEYLFKYLRALAAMYIRMTDVYELLEPLLKDYRKIRYRLTFIDEFVDSLLTEERVCDIILPRLQKR Schpo1 HEMLPTFLIGKILRERIVDSIYWKEQCFGLNACSLVD-RAVR-LEYIGGQYRPTEFICLLYKLLQIAPEKEIIQQYLFKYLRALAAFYVRLTEVHQTLEPLLRDYRKLRIRLTYLDEVVDDLLNAEVVCDISLPPLRSR Sorma NGLNPATIMEKAVRERIIDSYFYKEQCFGVNEADIVD-RVVEHVDYIGGVAKPTPFLCLAFKLLQLAPSDDILNEYLFKYLRALALFYIRLTDVYKTLEPFLEDRRKLRRKLTYMDVFVDDLLTKDRVCATSLWKMRKR Sphar HGRNPQHLVDKIIRTRIYDCRYWKEDCFALTAESLVE-KAVD-LNYCGGVYKATPFICLLLKMLQIQPDREIIVEFIYKYVRLLGALYLRLTDCYKYLEPLYDDFRCIRVKRSHVDEFVDELLHEERVCDVQMPRVQKR Spipu1 HGTNPQFLIEKIIRTRIYDSLYWKESCFALTAETLID-KAVN-LTSIGGQYKPTEFLCLALKMLQLQPEKEIVRLYIYKYLRALGAFYLRLTEIYQYLEPLLLDYRKLRRRLTHVDEFVDDLLRSERVCDTILPRITKR Sporo1 HGTNPQYLVPTVIRQRVYDTLYWKEHCFALDAASIID-KAVQ-LNHVGGTYRPTEFMCLVLKLLQLQPEREIVLEYLFKYLRALAAFYVRLTNVYEVLEPLLDDYRKLRFRVMTIDEFADELLTDEMVCEIQLPRLTQR Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 HGVNPAFLIEKITRERILDSLYFKDQCFGLTASTVLD-RVVG-LTYIGGIYRPTEFICLVFKMLQLAPEKDIILHYLFKYLRALAALYVRLVDVYLTLEPLLTDYRKLKVRLDYMDNFIDQLLTEPRVFDIALPNLMSR Thetr HGMDPQHLIDELTRSRVFRTRYYVSECVALDARSLLD-KAIC-LKYAGGTYRPTPFICLLLKMLQVQPAIEAVQAMIFKYLRLLAAMYLRLVIIYAALEPVLDDYRSLRVRRMHMDELIERLLVATELFGVILPRMPPR Treme1 HGSNPQYLIEKVIRARIYDSLYWKEHCFALNAESIID-KAIT-LHAIGGTYTPTPFICLTLKLLQLQPEKEILMEYLFKYLRALAALYIRLTDVYEILEPLMKDYRKLRIRLTYFDQFIDDLLKEERVCDIILPR---- Trire2 NGLNPATIMEKAVKDRIVDSYFYKEQCFALNEADIVD-RVVEHVTFIGGTHKPSPFLCLAFKLLELAPSDAILQEYLFKYLRALACFYVRLTDVYLTLEPFLEDRRKLRRKLTFVDEFVDDLLTKDRVCATSLWKMPKR Umbra1 HGTNPQFLIEKILREKITDSLYWKEHCFALTAATVLD-KAVD-LRGIGGQQKPTEFICLTLKLLQLQPEKEIVIEYIFKYLRALGAFYLRLVEIYQYLEPLLNDYRKLRLQIVHMDEFIDQLLREERVCDTILPRITKR Ustma22 HGTNPQFLIEKPVRARIYESPFWKEHCFALSAATILP-LAVS-LNHIGGLVRPSHFLCLLQKLLQIQPEPAIINAYLFKYLGALTAFYIRLTHVYTLLEPMLEDGRKLRWRILHMDEWVDMLLREERVCDIILPRLTRR Walse1 HGRNPQHLIENVIRQRIYESAYWKEQCFALTAETIID-KAVE-MQSIGGVYRPLPFICLLLKLLQLQPEPEIILEYLFKYLRALAAMYTRLCQVFDILEPLLQDYRKLRLRITHMDEFVDELLTEERVCDIILPRLTKR Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2696.fasta_al_trimmed; alignment length = 99] Allma1 EVGASSAPLTSAAFFIGAFCKEYNEDFMLC-KAEDPRHCLKEGRKVTRCTIDLLAKLKANCGEQFKAHWTCLDNKN--HCRAEERAFNQCVFDKLGLSK Ashgo11 --------------------------------------------------------------------------------------------------- Aspfu1 EIGATSAPLLSASYFIGDRCKAFNDDFMKC-KAEGELECLKEGRKVTRCAASVIKDINTHCLKQFNAHWECLENNN--QCRKPEMELNSCVFEKLGLKK Aurde31 ELGATSAPLKSAAFFIGRFCQAYNEDFMLC-KQEDPAHCLKEGRRVTRCATELINKLRENCQDQYDKHWDCLEKRN--QCRKAETALNQCVFDKLGIKK Batde5 EVGCTSAPLQSISFHFGAACKSYNEDYILC-KKEDPRDCLAEGRKVTRCALDFISKLKENCDESWTKHWQCLDMSN--QCRKEERQLNDCIFDKLGISK Botbo1 ELGVTSAPLKSAAFFIGAYCKEYNEDFMLC-KQENPAHCLKEGRRVTRCATDLIEKMRANCAEQFEKHWQCLELNN--QCRKPERVLNKCMFDKLGLTK Botci1 EIGSSSAPLLSASFFIGARCRPYNDDFMQC-KNDGEIDCLKEGRRVTRCARSVIEDVNKHCLEEFRKHWKCLDNNN--QCRPQEWKLNKCVFDNLKIEK Caeel EITLSTPWLKSIAPYMAKHCEKEANEFMLR-RKEDPRAVLKEGAALTACGVNFLQSLKRSCLPQTQKLAECVDQSSAKLCHDDQKELDACVEANLNLTR Canalb1 EVGATSAPLLSASYYIGDKCKPFNEDFLLC-KEEGTLECMKEGRRVTRCAISVLKDINKYCFDEFKLHYECLEQNN--QCRSSEGVLSKCVFDNMKLVK Cangl --------------------------------------------------------------------------------------------------- Capow EIKVTSSPLLAAAKHLGEYCDTPNRAYMQC-RFDNPELCLEEGRYVTECTAEFFKVLRGNCNERFTELWQCLDKNN--QCSAAQKALAACAKEKMSFLG Catan2 EVGSTSAPLHSASFFIGAFCKPYNDDFMLC-KQEDPRHCLAEGRKVTRCALDLLAKLKANCGQEYKAHWSCLDNSN--HCRPEERKLNDCVFDKLGLSK Cioin DLGVPSHVLKASAFQYANECNEVNKEFMLC-REEDPRKCLKYNIKVSDCAENFFRKMTTACADEIVAFGKCLERDH-KRCRDEQVKFDRCMFEKLGIDK CocheC53 ELGASSAPLLSASYFIGARCKPFNDDYMMC-KTEGEFECMKEGRKVTRCAASVIKDINENCLSQFRTHWQCLENHN--QCRSEERKLNKCVFDKLKLEK Coere1 EVGATGAPLKSASFVIGSMCKEYNEDFMLC-KDENPQHCLREGRKVTRCAIDVLEKIQANCRDEFRAHWQCLDDKN--QCRVPEKTYNECLFKSLGWKK Conco1 EVGATSAPLLSASFFLGEYCRPYFEDFMLS-KAEDPAHSLKEGRKVTRCATDFLAKLKEKCGDEYEAHWKCLDVNN--HCRPVEKKFNSCVLKAFNLKK Conpu1 EIGTSSAPLKSAAFFIGAYCKDYNEDFMLC-KQDDPGACLKEGRKVTRCATDLINKMRENCLETFDKHWQCLELHN--QCRKDERALNKCMFEKLGLTK Copci EIGATSGPLKSAAFFIGAHCREYNEDFMLC-KNEDPGHCLKEGRRVTRCAQDLLTKMQQNCMETFQAHFECLERNN--HCRKPERKLNACMFEKLGLTK Croqu1 ELGVTSAPLKSASFFLGSFCKPFTEDFMLC-KAENPEHCLKEGRRVTRCAQDAISKIKSNCLDEFNAHWQCLELNN--QCRKREKTFNTCLYDKLQWKK CryneH991 ELGVTSAPLKSASFFIGQHCKEVNEDFMLC-KQEDPAHCLAEGRKVTRCAQELISKLRETCLTEFDAHWQCLEKNN--QCRKPEKALNQCVFTKLGLTK Crypa2 ELGASSAPLLSASFFIGARCKDYNDDFMQC-KTEGEFECLKEGRRVTRCARSVIEDVNKHCLEEFRTHWQCLDNNN--HCRPAEWKLNKCVFHNLKIEK Debha1 EVGATSAPLLSASYFIGSKCKPYNDDFMLC-KDEGTLECLKEGRRVTRCAISVLSDINKYCFDEFKLHYECLEQEN--HCRNSESVLNKCIFQNMKLEK Dekbr2 EIGATTGPLLSASYYIGDRCHAFNDDFMLC-QKEGPVKCLKEGRRVTRCAASVIRDLNASCKKEFELHYKCLNYSN--MCRKAENLLNDCVFNNLKLIK Dicdi --------------------------------------------------------------------------------------------------- Dmel ELNLSSAALRAGAFHLGKQCEQANNEFMLC-RQEDPRACLAEGKAVTSCALDFFRKVKKTCHEEFTQYATCLDKSSGTMCRKTQGVFDKCIKDNFDWDR Enthi --------------------------------------------------------------------------------------------------- Falba SFQVTSSPLMASAFYIGEYCMQQNTKFMTC-HENAVDKCIDESVEVVKCASEIMNKVNAYCSDEFFRYWKCIDLNN--QCRQEQNVLDTCMFQSMGIGK Fomme1 ELGTTSAPLKSAAFFIGAYCKEYNEDFMLC-KAEDPAHCLKEGRRVTRCATDLITKMRENCLKEFDAHWECLEKNN--QCRKPERTLNKCMFEKLGLMK Fusgr1 EVGASSAPLLSASFFIGARCRDYNDDYMQC-KNEGEFECLKEGRRVTRCATSVIKDINTHCLAEFRKHWECLDDRN--HCRPAEWKLNKCVFDNMKLEK Galma1 EVGATSAPLKSAAFFIGAYCKEYNEDFMLC-KKENPGHCLKEGRKVTRCATDLITKMRENCASQFDAHWNCLEKKN--QCRQPERKLNACMFEKLGLTK Ganpr1 EVGATSAALETASFFLGAHCKDVNEDFMLC-KSEDPKHCLKEGRRVTRCAQDMIRKLKANCETEWRTYYEAYDWNN--HVRKEEKAFSECVFAKLGLEK Gloin1 EVGATSAPLKSASFFIGAYCKDFNDDFMLC-KNEDPKHCLKEGRKVTRCTIE----------------------------------------------- Hisca1 EIGATSAPLMSASYFIGDRCRAYNDDYMKC-KMEGELDCLREGRKVTRCAASVIKDINENCLEQFKAHFECLEQNN--HCRRPENALNTCVFEKLGLKK Klula1 --------------------------------------------------------------------------------------------------- Lacbi2 EIGVTSAPLKSAAFFLGAYCKEFNDDFMLC-KNEDPGHCLKEGRRVTRCATDLITKMRENCLQQFESHWECLERNN--QCRKPERTLNSCMFEKLGLTK Lenti61 ELGVSSAPLKSAAFFLGAFCKDYNEDFMLC-KAEDPAHCLKEGRRVTRCAQELITKLRENCLSEFEKHWNCLENNN--QCRKDERVLNKCVFEKLGLVK Malgl1 EVGATSAPLKSIAFFFGQFCQPYAEDFMLC-KNEDPEHCLKEGRRVTRCAQDLIQKIGEKCGNEWDAHWQCLEKNN--Q----------------NLIK Mellp23 ELGVTSAPLKSASFFMGSFCKPFTEDFMLC-KAENPEHCLKEGRRVTRCAQDAIAKIKSSCLEEFNSHWQCLEMNN--QCRKPEKTFNGCLYDKLQWKK Mnele DYNVTSVPLLAVADHLGQVCKDANDRYMLC-RNDDPRKCLREGQLVTNCTKMFMDKVYKECKMPFARYTTCLDLNT--RCRGTQIEFDKCMLEKTGVSR Monbr --------------------------------------------------------------------------------------------------- Morel2 EVGATSAPLKSAAFFIGSYCKDYNEDFMLC-KDEDPAHCLKEGRKVTRCAMDLITKLRENCEKEWEAHYKCLEKHN--QCRKPERTFNECVFSKLKLEK Mucci2 EIGATSAPLKSASFFIGQYCKEYNDDFMLC-KNEDPKHCLSEGRKVTRCAINLITKLRENCGKEFEAHWQCLEKNN--QCRTPERTFNTCVFEKLGLEK Mydma ELPATSSVLYAGAHHLGNYCKQDFTTFIQK-RYEDPRATLEEGKKVTECALEFFRKLRKDCNKEFTDHWKCIDYNN--HCRKTQAVYDDCVFKNFNLTS Neucr2 ELGASSAPLMSAAYFIGARCRDYNDDFMQC-KNEGEFECLKEGRRVTRCARSVIADINKSCLEEFRKHWTCLEDNN--QCRPAEWKLNKCVFENLGLKK Orpsp11 --------------------------------------------------------------------------------------------------- Pench1 EVGATSAPLMSAAYFIGDRCKAFNDDFMKC-KDEGEIDCLKEGRKVTRCAASVIKDINTHCLDQFKAHWECLENNN--HCRRAEMQLNNCVFDKLGLKK Phybl2 EVGATSAPLKSASFFIGQYCREYNDDFMLC-KNEDPAHCLKEGRKVTRCAIDLITKLRENCGKEFDAHWQCLENHN--QCRKPERTFNTCVFEKLGLEK Picst3 EVGATSAPLLSASYYIGAKCKPYNDDFMLC-KDEGTLDCLKEGRRVTRCAISALKDINKYCFDEFKLHYECLEQEN--HCRASESVLNKCLFQNLQFEK Plicr1 ELGTTSAPLKSAAFFLGAYCKEYNEDFMLC-KQEDPAHCLKEGRRVTRCATDLITKMRENCLQQFDAHWNCLEQNN--QCRKPERTLNKCMFEKMGLTK Polpo --------------------------------------------------------------------------------------------------- Pucgr2 ELGVSSAPLKSASFYIGSFCKPYSEDFMLC-KAENPEHCLKEGRRVTRCAQEAITKIKAACLDEFTSHWKCLDRNN--HCRKPEKDLNACLFQKLQFKK Punst1 ELGATSAPLKSAAFFIGAHCQEYNDDFMLC-KEEDPAHCLKEGRRVTRCAQDLIAKMRENCAKEFEAHWNCLEHNN--HCRKQERPLNNCMFEKLGLKK Rhior3 EVGATSAPLKSASFFIGQYCKDYNDDFMLC-KSENPEHCLKEGRKVTRCAIDLIAKLRENCGKEFEAHWQCLENNN--QCRKPEGVFNTCVFEKLGLKK Rhoto1 ELGVTSAPLKSASFFLGEYCKPYNEDFMLC-KAEDPEHCLKEGRKVTRCAQDLIAKVRSTCLKEFDAHWQCLENNN--QCRKEERVFNNCVFEKLKLKK Rozal11 --------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------- Salro EMKETSAVLKAAARHMGQACAEVSLGYMRCKKANDPTKCLEQGEAVTKCGIEFFKALRSNCGAELDAQAECLESNN--HCRKTQSALDECVFEKMNLDG Schco3 ELGVTSGPLKSAAFFIGAYCKEYNEDFMLC-KAEAPEHCLAEGRKVTRCAQDLITKMRENCLSEWNKHWDCLENHN--QCREVERPLNKCMFEKLGLLK Schpo1 --------------------------------------------------------------------------------------------------- Sorma ELGASSAPLI--------RCREYNDDFMQC-KNEGEFECLKEGRRVTRCARSVIADINKSCLEEFRKHWTCLEDNN--QCRPAEWKLNKCVFENLGLKK Sphar -----MSVLLAGARHYGQYCKAQNDAFMYC-KYDDPAKCVEEGKKVTACGIEFFQKLKDNCNAEFTAHWQCLDTSN--QCRKTQKAFDDCVFQKMGLSG Spipu1 EVGCTSAPLESMSFHFASYCKAYSEDYMLC-KNEDPRHCLKEGRKVTRCALDLIRKLKENCDKEWTRHWECLDVNN--HCRKEEREFNDCVFKKLGLTK Sporo1 ELGVTSAPLKSASYFIGEFCKPYNEDFMLC-KSEDPAHCLKEGRKVTRCAQDLISKVRSTCLKEFDAHWQCLERNN--QCRKPERVFNNCVFEKLKLKK Stehi1 ELGTTSAPLKSAAFFIGAHCKEYNEDFMLC-KAEDPAHCLKEGRRVTRCATDLINKMRENCLESFDAHWDCLEYNN--HCRKPERVLNKCMFEKLGLVK Tapde11 --------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------- Treme1 ELGTTSAPLKSASFFIGQYCKDVNEDFMLC-KSEDPAHCLKEGRKVTRCASELIRKMRESCLAEFDAHWQCLEKNN--QCRVPEKALNNCVFTKLNLTK Trire2 EIGASSAPLLSASFFIGARCRDYNDDYMQC-KTEGELNCLKEGRRVTRCAQSVLTDINTHCLAEFRKHWECLDNRN--QCRPAEWKLSKCVYENLKLEK Umbra1 EIGLTSAPLKSASFFIGQYCKDYNADFMLC-KNEDPEHCLKEGRKVTRCALDLIKKLRENCDAEFEKHWKCLDVKN--QCRKEERQFNSCVFEKLGLQK Ustma22 ELGVTSAPLKSASFFIGEHCKDVNEDFMLC-KNEDPAHCLKEGRRVTRCARDLIKKLSDSCGKEWEAHYQCLEQHN--QCRKPEKTLNQCVFEKLKLAK Walse1 ELGVTSAPLKSASFFIGDKCKEYNDDFMLC-KQENPEHCLKEGRKVTRCAASVISDINKHCFKQFESHFQCLEFNN--QCRKQERSLNECVAASLNLHK Zygro1 --------------------------------------------------------------------------------------------------- [Cluster2700.fasta_al_trimmed; alignment length = 41] Allma1 LLLVNAIAVLNEVKAKLIGLMSAVRTLMRIAINTVAIVYML Ashgo11 LLLVNAVAVLSETKSKLVHLISAVQTLLRIGINILVILYEL Aspfu1 ----------------------------------------- Aurde31 VLFINAVAILSEVKVKLISLIGAVRTLMRIAFNLIFILYEL Batde5 LMVVNAIAVLHEIKLKLVNLIAAVRTLLRVALNIVVIIYEL Botbo1 LLLVNAIAVLNEVKARIINLIGAVRTLMRILLNIVVIVYEL Botci1 VLLTNAVAILSEIKSKLVNLMTSVRTLMRIGINSVIIIYEL Caeel LLVLNGIAILHRVKDQLVSLIFAVQTVMRIAINIVVIVFKL Canalb1 VLVINGIAVLSEVKTKLINLISAVRTLMRIVVNITIIIYEL Cangl LLLINAVAVLSETKSKVVQLIGAVQTLLRIGINILVIVYEL Capow LLFFNAIAVLNEAKARVMLLIHDVRKYMRILLNVCVISLKI Catan2 --MVNAVAILHEVKVKVIGLISAVRTLLRIIVNTLTILYLF Cioin ----------------------------------------- CocheC53 VLLINAIAILSEVKARLINLVSSVRTLMRMFINTLMIIYLI Coere1 LLLLNGVAILNEIKAKLINLISAVRTLMRIVVNVVVIVYAL Conco1 ----------------------------------------- Conpu1 LLLINAIAVLSEVKGQLINLISAVRTLMRIGVNLVVIVYEV Copci LLLINAIAILNEMKARMIDLISAVRTLMR-TWKSLTIRYST Croqu1 LLLINSLAILNEIKDRLVNLIGAVRTLMRIGLNIVVIIYEL CryneH991 LLFTNAIAILNEVKAKLVNLIGATRTLMRIVVNIGVIIYEV Crypa2 VLLINAIAILSEVKGKIISLIASVRMIMRIIFNTLIIVYEL Debha1 ILTVNGIAVLSEVKTRMINLISAVRTLMRIFINVVVIFYEL Dekbr2 LFFVNGIAVLSEVKSRLINLISATRTLLRIAINIIIILYDI Dicdi LLIVNSFAILNEFKGKIITLLHSLRFFFRMFSNI------- Dmel LLCLNAVCILHEAKDQVLNLIRSIRTVAKIFLNIIAIIFKL Enthi LLFVNSIVILNQVRGRLSWFFYRTQDLMKIVLNTIVIGFLL Falba LLFVNAVAVLNELKLQIIRLIASVQTLLKIILNVVWIAFEL Fomme1 LLLINAMAILNEITAKLVNLITAVRTLMR------------ Fusgr1 ILLINAVAVLSEVKAKIINLIASVRTIMRIFVNSVIILYEL Galma1 LLMINAIAILSEMKTRIIDLISAVRTLMRIVINTVVILYEL Ganpr1 VLFINGVAILHELKTRLVTLIAAIRTLLRILANVLIITYEI Gloin1 LLVINAIAILNEFKSKIINLISAVRTLMRIVLNILVIIYEI Hisca1 VLIINAIAILSEIKAKSVNLIASVRTVMRIIINLIIIIYEI Klula1 LLLINSIAVLSETKSKLVQLIGAVQTLLRLVVLLITIIKQL Lacbi2 LLIINAIAILNEMKDRLVDLIGAVRTLMRIAINTLVILYEL Lenti61 ILLVNAMAVLSEVKGRMINLIGAVRTLMRIGLNLVIIGYEL Malgl1 LLLVNSIAILNEVKQRLIHLISAVRVLLR------MIIYEL Mellp23 LLLINSLAILNEVKERLVNLIGAVRTLMRIGINIVVIIYEL Mnele VLLINALAILNEVKTRLIELISSVRTLMRIFVNSLVIVLEL Monbr LLFINAVAVLQDVKGKIVTMINAVRTLMRIAVNAVMIVYLL Morel2 LIFINAIAILNEIKARLVNLISAVRTLMRIGLNIVAILYLV Mucci2 LCFINAIAVLSEIKYKIINLISAVRTLMRIGINIVVIIYEL Mydma ----------------------------------------- Neucr2 CLLINAIAILSEVQAKIMNLIASVRTLMRILVNTLIIIYEL Orpsp11 ----------------------------------------- Pench1 ILIINAIAVLSEVKAKSVNLIASVRTVMRIVINTVIVVYEL Phybl2 LCFINAVAVLSEIKSKMVNLISAVRTLMRIAINIIVIIYEI Picst3 ILTVNGIAVLSEVKTKIINLIGAIRTLLRIAINVVVILYEL Plicr1 LLLVNSVAVLSEMKIRLINLITAVRTVMRIGFNILIIIYEL Polpo ----------------------------------------- Pucgr2 LLLINSLAILNEVKERLINLIGAVRTLMRIGLNIVVIIYEL Punst1 VLLINSIAVLSEVKGRLINLISAVRTLLR------------ Rhior3 ----------------------------------------- Rhoto1 LFMVNAVAVLNKIKMRAVQLVDAVRTLMRIPINILVVVYLI Rozal11 LLLLNAVAVLNELKKKTLEKIKEYSENVRLPIDSLIVQDSI Sacce1 LLLINAVAVLSETKSKVVQLIGAVQTLLRIGINILVIVYEL Salro LLLVNAVAILQDVKGKIITMINAVRTLMRIFVNLLVAVYLI Schco3 ILLVNAVAVLSEIKARIIDLIAAVRTLLRIGINTVIILYEL Schpo1 LLLLNAVAILSEIKSRILHLIRAIRTVMTIAINTIVIVYNL Sorma CLLINAIAILSEVQAKIMNLIASVRTLMRYYIHTSIDTYMI Sphar -------MTLDGAKDKMAALIYAVRTLTRIGMNLVAIIFKV Spipu1 ----------------------------------------- Sporo1 LLVINAIAVLSKVKMRAVQLVDAVRTLMRIPINIAVVIYEI Stehi1 ----------------------------------------- Tapde11 ----------------------------------------- Thetr LLLVNALAILHEVKDQISNLLKSVRMLLRIVVNIIVMAYAM Treme1 ----------------------------------------- Trire2 CLLTNALAILSDVKAKLVALIASVRMVMRIIVNTLIILYEL Umbra1 LLFINAIAVLNEIKSKIVNLISAVRTLLRIGINILVIMYEL Ustma22 LFITNALAVLSEIKARLINLISAVRTLMRMAINIVVVIYLI Walse1 LLLTNSVAILNEVKTRLINLISAVRTLMRIILNIIVIVYEL Zygro1 LLLINAVAVLSETKSKIVHLIGAVQTLLRIGINILVIVYEL [Cluster2707.fasta_al_trimmed; alignment length = 50] Allma1 KMGAMMGCGVGVGLGFVIGG-KGYLGTLANAITTSGASFGFFMAVGSVIR Ashgo11 KMGLMMGTTVGICTGILFGP-NGVIRSLGQYIAVSSATFGLFMSIGSVIR Aspfu1 KMGALMGSTVGGIMGFIIGP-NGVMRTLGKYMLGSGATFGLFMSIGSVIR Aurde31 -MGAMLGGGVGLTIGFIFGP-RGFLATLSQYMLTSAATFSFFLAIGSVIR Batde5 KMGFLMGATVGMTTGFIYGPGKSYVQSVGKHMLQQGSMLGFFLSIGSLLR Botbo1 KMGAMMGGGVGLTIGFIFGP-RGFLATLSQYMLSSAATFSFFLAIGSVIR Botci1 QMGAMMGGTVGAILGFMY--------------------FSWPLAVPSV-- Caeel -------------------------------------------------- Canalb1 KMGAIMGSTVGVCVGVLFGP-NGVMRTLGQYIMGSVGTFGLFMSIGSVIR Cangl KMGLMMGSTVGVCTGVLFGP-DGIMRTLGKYIAGSAATFGLFMSIGSIIR Capow -------------------------------------------------- Catan2 KMGAMMGTGVGVGLGFILGG-KGYLGTLSNSVMTSGITFGFFMMVGSVIR Cioin -------------------------------------------------- CocheC53 KMGGMMGGSVGLIIGFIFGP-NGMLRTLGQYMMGSAATFGFFMAIGTTIR Coere1 KMGLIMGGSVGACLGCLIGP-RGYLGTIGQYALGSGASFGFFMMIGSCIR Conco1 -------------------------------------------------- Conpu1 AMGAMMGTGVGLTIGFIFGP-RGALSTLSQYMLSSAATFGFFLSVGSVIR Copci -MGALMGGGVGLTIGFIFGP-RGFMATLSQYMLSSAATFSFFLAIGSVRR Croqu1 GMGAAMGGAVGMTLGFLFGP-RGPLNTLATYMLSSGGTFAFFMSIGSVIR CryneH991 KMGAIMGSCVGLTIGFIFGP-RGVVATLSQYMLSSAATFGFFMSVGSVIR Crypa2 KMGAMMGGTVGVIIGFIYGP-NGIMRTLGQYMGASGATFGFFMSIGSIIR Debha1 KMGAIMGSTVGVCVGVLFGP-NGVMRTLGQYIMGSVGTFGLFMSIGSVIR Dekbr2 KMGLAMGSAVGVVTGFMFGP-KGVINTMGQYILGSAAAFGMFMSIGSVIR Dicdi -------------------------------------------------- Dmel KTGFIIGFCVGMASGAVFGG-RELINNVGKTMVQGGGTFGTFMAIGTGIR Enthi -------------------------------------------------- Falba -------------------------------------------------- Fomme1 EMGAMMGAGVGLTIGFLFGP-RGIMATLSQYMLGSAASFTFFLAIGSAIR Fusgr1 KMGAMMGGTVGVIMGFVFGP-NGIMRTLGQYMAGSGATFGFFMSIGSVIR Galma1 RMGALMGGGVGLTIGFIFGP-RGALSTLSQYMLSSAATFSFFLAIGSVIR Ganpr1 KMGALMGGTVGVCLGFLFGQ-HGYMGTMSRAMLSSGTTFGFFMGIGTVIR Gloin1 KRGVIMGSAVGVCLGLALGP-RGFISTLGQYMATSAGSFALFMGVGSAIR Hisca1 KMGAMMGGSVGLIMGFIMGP-NGVMRTLGKYMID-------FLCRLEALS Klula1 KMGLMMGTTVGVCTGILFGP-NGFVRTLGQYIAGSAATFGLFMSIGSVIR Lacbi2 QMGAVMGGGVGLTIGFIFGP-RGFMATLSQYMLSSAATFSFFLAIGSVIR Lenti61 KMGAAMGAGVGLTMGFLFGP-RGVLPTLSQYMLGSAATFSFFLAIGSVIR Malgl1 -------------------------------------------------- Mellp23 GMGAAMGGAVGMTLGFIFGP-RGPLNTLATYMLSSGGTFAFFMSIGSVIR Mnele KTGAFMGAALGCGVGFMFGG-KKLINELGSTMLQSGGTFGTFLAIGSAIR Monbr KGGFVVGGALGLAAGGVYGG-RKLLRGTALQMLTFGATFGFFLAVGTGIR Morel2 KYGAAMGGAVGLCIGLVFGR-NGYVNNLAQTMMSSTAMFAFFMAIGSVIR Mucci2 KMGAAMGGTVGLCIGFVFGN-KSPISMLSQYMIGSAASFGFFMSIGSVVR Mydma -------------------------------------------------- Neucr2 KMGAMMGGTVGCIIGFIFGP-NGIMRTLGQYMLGSGATFGFFMSIGSVIR Orpsp11 SRGALSGASVGLCIGFIYGN-GGIASTIGKSMAGSAASFGFFM------- Pench1 KMGCMMGSTVGGIMGFIIGP-NGVMRTLGKYMLGSGATFGLFMSIGSVIR Phybl2 KMGALMGGTVGLCVGFVFGT-KGPVTLLSQYMLGSAASFGFFMSIGSVIR Picst3 KMGAIMGSTVGVCVGVLFGP-NGVMRTLGQYIMGSVGTFGLFMSIGSVIR Plicr1 RMGALMGGGVGLTIGFIFGP-RGFLATLSQYMLSSAATFSFFLSIGSVIR Polpo -------------------------------------------------- Pucgr2 GMGAAMGGAVGMTLGFLFGP-RGPLNTLATYMASSGGTFAFFMSIGSVIR Punst1 KMGAMMGTGVGLTIGFIFGP-RGVMATLSQYMLSSAATFGFFLSIGSVIR Rhior3 KMGAAMGGTVGLCIGFVFG------------------------AIGSVVR Rhoto1 RMGMLTGGLVGLTIGFIFGR-KGYLPTLSTYMLSSGATFAFFMSIGTVIR Rozal11 KLGVFMGGIVGCCIGFVFG--QRYLRTVFQYMATSGASFGLFMGVGSVLR Sacce1 KMGLMMGTTVGVCTGILFGP-DGVVRTLGKYIAGSAGTFGLFMSIGSIIR Salro -------------------------------------------------- Schco3 KMGFIMGAGVGLTTGFIFGP-RGALSTLSQYMLASGGMFSFFLAVGSVLR Schpo1 KMGAIMGSAAGLGIGFLFGP-RGFLRTLGQYMLTSAATFGFFMSIGSVIR Sorma KMGAMMGGR----------P-NGIMRTLGQYMLGSGATFGFFMSIGSVIR Sphar -------------------------------------------------- Spipu1 KMGFMMGASAGMCVGFLYGPGRGYMSTVGKYMLQHGAMLGFFLSIGAFLR Sporo1 KMGAFTGGMVGLTIGFIFGP-KGFLPSISTYMLSSGATFAFFMSIGSVIR Stehi1 KMGALMGGGVGLTIGFIFGP-RGALATLSQYMLSSAATFSFFLSVGSVIR Tapde11 KMGALMGTTVGCCVGILFGP-QGFLRYIGQNMAASAAMFGGFMSIGSVIR Thetr MYGAMMGGAVGVSFGVLFGD---FVRFVGKAAAGSGSTFAVFMAVGAFVR Treme1 KMGAMMGSMVGLSIGAIFGP-RGVVATLSQYMLSSAATFGFFMSIGSVS- Trire2 ---------VGVIMGFIFGQ-QGIMRTLGQYMGASGATFGFFMGVGSVIR Umbra1 KMGAMMGGTVGLCVGLVFGQ-RGAISMLGSYMAGSAASFGFFMSIGSVIR Ustma22 KMGAMTGTLVGLTIGFIGGP-RGALGTLSQFMLSSAATFGFFMSIGTVLR Walse1 KMGALMGSTVGLTIGFIFGP-RGVMGTLSQYMLSSAATFGFFMSIGSVIR Zygro1 KMGLMMGTAVGVCTGVLFGP-DGFVRTLSKYIAGSAATFGMFMSIGSVIR [Cluster2717.fasta_al_trimmed; alignment length = 187] Allma1 ----------------------------------------M-RRTVEAIVVVHVHNHPHVLLLQIAPGDYLQPGE--DEIEGLKLRLNKQLSRWDIRECIGQWWRTNFESF-LYPYLPAHITRPKENKKVFLVLLPPQTLWIPRNLKLMAVPLFEIYENSSRFGNQISAIPYLLSRF---------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 TIRLYPL-SNYTFGTKETQPEEDPSVARLKRLEEHYEKHGM-RRTCEGVLVCHEHNHPHVLMLQIAPGDYLHFDD--DEVEGFKKRLNERLAPWEIGDTLAQWWRPNFETF-MYPFLPGHVTRPKECKKLYFIQLPKKVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPRTKVLA-GE Aurde31 TVLLYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEFEGLKARLDDRLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Batde5 TVSLYPL-SGFSFGAKDPQMEDDQTMAKLNRLQSEFEIQGM-RTSVEGVLLVHEHGHPHILMLQVAPGGILKPGE--DEIEGLKLRINQKLAPFDVGELIGVWWRPSIESI-MYPYVPAHISRPKEMRKVYLIHLPEKLLSVPKNMKLLAVPLFELYDNAARYGPHLTTLPNLLSRF---------- Botbo1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLKNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DDSDGLKARLDERLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLYLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Botci1 ----------------------------------------M-RRTCEGILVCHEHNHPHILMLQIAPGDYLKPED--DEVEGFKQRLNERLAPWEIGDTLAQWWRPNFETF-MYPFIPAHVTRPKECKKLYYIQLPRQVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPKTIVLAGGD Caeel TINVYPL-TNYTFGTKDAQAEKDKSVERFKRMKDEYEVMGM-RRSVEAVLIVHEHSLPHILLLQIGPGGELELGE--DEISGVTRLLNETLGRWTIEDEIGNWWRPNFDPP-RYPYIPAHVTKPKEHTKLLLVQLPSKTFCVPKNFKLVAAPLFELYDNAAAYGPLISSLPTTLSRF---------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow DVNLFPL-TNYSFGIKDPQYERDPSVTRMQRLKDEFEQYGS-RRTVEAVLLVHEHNHPHLLLLQLGPGGELDIGE--DEITGCQRWLTKTLAVWNVCEIVCNWYRPSYDQN-QYPYIPGHVTRPKEHRRVFVVELPPNALAVPKNYKLVAAPLFELHDNPQTYGPVIAQLPAMLSRI---------- Catan2 KVTLAPL-SSLRFAQKDEQHEEDTSVARLERLQRQFDAQGM-RTTVEAVIVVHAHNHPHVLLIQIAPGDYLKPGE--DLVSGLKAKLNQQLSRWDVVECVGQWWRPNFETF-LYPYLPPHITRPKENKKIFLVNVPPGTLWIPRNLKVMAVPVFELAENSSRFGNQISAIPHLLSRF---------- Cioin GINLYPL-TNYTFGTKEPLYERDSTVARFQRMREEFDKAGQ-RRSVEGVLIVHEHGLPHVLLLQLGPGGELHNGE--NEVDGLKRLMTETLGRWVIEDCIGNWWRPNFEPP-LYPYIPAHITKPKEHKKLFLVQLGEKLFAVPRNYKLVAAPLFELYDNSNGYGPVISSLPQLLSRF---------- CocheC53 TIRLYPL-SNYTFGTKDGQPEEDPSVARLKRLEEHYSEHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLRAED--DEIEGFKARLNERLAPWVVGDTLAQWWRPNFETF-MYPFIPAHVTRPKECKKLYFIQLPRSVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPQTKVLAGGD Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIDGLKRRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Copci TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKKRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Croqu1 TVTLYPL-SNYTFSTKEAQPEEDPSVSRLQRLQNNYEDFGM-RRTVEGILVVHEHGHPHVLMLQIAPGDYLRPGE--DDIEGLKERLDERLAPWEIGDCLSQ-------GF-EYPYVPAHITKPKECKMLYLVQLPEKVLSVPKNMKLLAIPLFELYDNPQRYGPQLAAIPHVLSRF---------- CryneH991 TIEAFPL-RNYLFIEREGQPEEDNSVNRLKRLEDQYTESGT-RRSVEAIMVVTVHGFPHVLVLQVAPGGYLDPSE--SDAEGLITRLNEQLGVWEVRDCLSVWYRPHFDTF-ILTYLSV-------------------TFAVPANMKLHAIPVFEFYDNAARYGPQFAGIPYILSRF---------- Crypa2 TIRLFPL-SNYTFGVKETQPEEDPSVARLKRLEEHYTQHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLKPED--DEIEGFKKRLDERLAPWDVGDCLAQWWRPNFETF-MYPFVPAHVTRPKECKKLYIIRLPESVLSVPKNMKLLAVPLFELYDNSQRYGPQLSAIPHLLSRYPKAKVVA-GD Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi TLTLYNFNTSYSFG-KEEKKEKEQSLSKLARLKDSYEKEGL-RKAVEGIIIIHDHGHPHILLLQ-DPGGKLKPGE--NEIDGLIRKLTKKLSPWEIGDHVSTWWRPNFEPS-LFPYIPSHITKPKECKKLFVVTLPEKKFAVSNNLSLIAVSLYEIYNNSQRYGAVISSIPALISRY---------- Dmel TINLYPL-TNYTFGTKEPLFEKDPSVSRFQRMREEFDRIGM-RRSVEGVLLVHEHGLPHVLLLQLGPGGELNAGE--DEVEGLKRLLSETLGRWIVEDTIGNWWRPNFEPP-QYPYIPPHITKPKEHKRLFLVQLHEKLFAVPKNYKLVAAPLFELYDNSQGYGPIISSLPQALCRF---------- Enthi ------------------------------------------------------------------VGGRLKIGE-DDPVEGLKRKLRKKMSMYEIGELLGTFYRIEYDKN-LYPYIPVHVSQVKEIINIYMIHLVEKDFKIFDTDKLSSIPLFALHNNFEKYNITLCSIPTLVSRY---------- Falba TLRLYQA-ENYTTGTREKQPEPDASVARFARLKDEYALHGM-RHSVAAAIVIAKHGHPHLLCLRIAPGDELLPHEYADPVAALKNRLDLQLAPWEVKSRVATWWRPNFEHS-VYPYIPAHITRPKEKQLIYLIQAPPSQFFIPANYTMQLIPFWELH-NSKSFGPIISAIPQSLSRM------VSGD Fomme1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGVLVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKRRLDERLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLFLVQMPEKVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Fusgr1 KVTLYPL-SNYTFGVKETQPEEDPSVARLKRLEEHYTEHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLRPED--DEIQGFKSRLDERLAPWQVGDCLAQWWRPNFETF-MYPFIPAHVTRPKECKKLYFIQLPKQVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPHVKVLA-GD Galma1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKRRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLFVVQMPEKVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Ganpr1 TAPLFPL-GNYTFGVKDHMSEQDPSVARLQRLAHEYEERGQ-RTTVEGVIVVHDHGHPHVLMLQIAPGEALNPGE--DEIQGLKVRLSQMLSPWEIGELIGVWWRPNFETF-MYPYVPAHITHPKEQKKLFLVHMPERVLAVPRNMKLLAVPLFELYDNAARYGQQLSALPHLLSRF---------- Gloin1 TVTLYPL-VNYTFGTKEAQPEEDPSVARLQRLQNDYETTGM-RRTVEGVLVVHEHNHPHVLMLQIAPGDYLKPGE--DEIEGLKARLDERLAPWQIGECLSVWWRPNFETF-MYPYTPAHVTKPKEQKKIFLVHLPEKILSVPKNMKLLAVPLFELYDNAQRYGPQLSAIPHLLSRF---------- Hisca1 TIRLYPL-SNYTFGTKETQPEEDPSVARLKRLEEHYEKYGM-RRTCEGVLVCHEHNHPHVLMLQIAPGDYLHHDD--DEVEGFKTRLNERLAPWEIGDTLAQWWRPNFETF-MYPFLPGHVTRPKECKKLYFIQLPKKVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPQTKVLLSGE Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIDGLKRRLDERLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Lenti61 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKKRLDERLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 TVTLYPL-SNYTFSTKEAQPEEDPSVSRLQRLQNNYEDFGM-RRTVEGILVVHEHGHPHVLMLQIAPGDYLRPGE--DDIEGLKERLDERLAPWEIGDCLSQWWRPNYESF-MYPYVPAHITKPKECKMLYLVQLPEKVLSVPKNMKLLAIPLFELYDNPQRYGPQLAAIPHILSRF---------- Mnele VVQLYPL-SNYTFGTKEPQYEKDASVARFQRMRDEYASIGM-RKTVEGVLLVHEHNLPHVLLLQLGPGVEVAPGE--DEVECLKTCLSETLGRWGVDEMICNWWRPNYEPP-QYPYIPPHVTKPKEHRRLFLVRLPERMFAVPRNYKLVAAPLFELYDNSNGYGPVISALPQNLSRF---------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma TVYLYPL-SNYTFGTKEALYEKDSSVARFQRMRDEFDTLGM-RRNVEGCLIVHEHGLPHILLLQLGPGGELMAGE--DESEGLKRSMSEMLGKWQCEDVLSNWWRPNFETP-IYPYIPAHITKPKEQKRIFLTQLPEKTFNVPRNYKLVAAPLFELFDNPQGYGPVISTLPCLLSKY---------- Neucr2 TIRLYPL-SNYTFGVKETQPEEDPSVARLKRLEEHYNAHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLRPED--DEIEGFKQRLDERLAPWQVGDCLAQWWRPNFETF-MYPFVPAHVTRPKECKKLYFIQLPKSVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPKTKVLASGD Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 TVRLYPL-SNYTFGTKETQPEEDPSVARLKRLEEQYRLHGM-RRTCEGILVCHEHNHPHVLMLQIAPGDYLHHED--DEIEGFKKRLNERLAPWEISDTLAQWWRPNFETF-MYPFLPAHVTRPKECKKLYFIRLPKKVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPPRVLLS-GD Phybl2 EATLYPL-ENYTFGAKDAQPEEDPSVTRLKRLEHDFETQGM-RRTVEAVLVVHQHNHPHVLMLQIAPGHYLKPGQ--DEQDGLKEVLNHRIGSWVIGECLSTWWRPNFESY-MYPYVPAHITSPKEKKMLYFVHMPPNVLSVPKNMKLLAVPLFELYDNSARYGAQLSAIAHLLSRY---------- Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKTRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Polpo ELSTTGY--YYSFGTKEPVKEKDSSVSRLARMKENFEKEGL-RKTVEAIIIVHNHNHPHILLLKIAPGGKLKPGE--NEIDGLIRKLTKKLSPWEVGENIATWWRPNFEQI-LYPYIPPHITKPKECKKLYVVTLPEKTFAVPSNLELIAVPLFEIYNNSQRYGAIISSIPQLISKY---------- Pucgr2 TVTLYPL-SNYTFSTKEAQPEEDPSVSRLQRLQNNYEDFGM-RRTVEGILVVHEHGHPHVLMLQIAPGDYLRPGE--DDVEGLKERLDDRLAPWEIGDCLSQWWRPNYESF-MYPYVPAHITKPKECKMLYLVQLPEKVLSVPKNMKLLAIPLFELYDNPQRYGPQLAAIPHVLSRF---------- Punst1 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDWGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKRRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFIPAHITKPKECKKLFLVQMPERVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Rhior3 KATLYPL-ENYTLSTKEAQPEEDTSVARLRRLEADYNQHGM-RRSVEAVLVVHQHNHPHVLMFQIAPGHYLEPEV--DEAEGMKEILNKKLGPWTIGECLSTWWRPNYENY-MYPYVPAHVTSPKEKKSLYIVHLPPNVLSVPKNMKLLAVPLFELYDNSARYGAQLSTIAHLLSRY---------- Rhoto1 TLKVYPL-SNYSFATKEAQVDEDPSVARLQRLESDYAQYGM-RRTVEGVMVVHEHGHPHVLLLQIAPGDYLKPQE--SNEEGLKMRMHEKLGPWQVGEAIGQYFRPNFESF-MYPYMPAHITKPKEIKTWYLMQMPERVLTVPKNMKLVALPLFELYDNAVRYGPQLASLPALLSRI---------- Rozal11 ---IFPL-SNYFIGVKDIVSDDYLSSKKIEQLEKDYPTLGL-HVSVEAVIVAHEHNHPLIFT----PGGFLKIGE--DEVEGLKRILNDLLAPWEIGEVISHWWRPHFTMD-MYPYPLPHIKQQKELKKVFLVGLPEKTFSVPKAFKVAAVPMIDVYENRANFGAIISSIPHVLSRF---------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro HVDIFPN-SNYKILKDDSKTEPKSAMEKLMALMHKFNETGL-VETMQLVMLVEQHGHPHVLLLQPHPHTEIKPDE--TSKETVHRILQEQFQVFRIVDLAAVWWRPHFEQP-TYPYQPPHVTKPKERIQVVLVQMPESDFVVPGNGNVRAVPLIELYDNKESFGQLIATLPQTLSRY---------- Schco3 TIALYPL-SNFTFSTKEAQPEEDPSVARLQRLQNNYEDFGM-RRTVEGVLVVHDHGHPHILMLQIAPGDYLKPGE--DEVDGLKRRLDERLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPEKVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma KIRLYPL-SNYTFGVKETQPEEDPSVARLKRLEEHYSAHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLRPED--DEIEGFKQRLDERLAPWQVGDCLAQWWRPNFETF-MYPFVPAHVTRPKECKKLYFIQLPKSVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPKTKILASGD Sphar ------------------------------------------------------------------PSGELHPGE--GEIEGCKRILTECLSPWEVADILSNWYRPNFEIS-RYPYCPAHITKPKEHTIVMLIQLPEFTFAVPKNYKLVAAPLFELYESSGTYGYTIASLPLVLSRFPPAAV----- Spipu1 TVTLHPL-SSYTFGVKDPQPEEDPSVARLLRLQSEYQTQGM-RITVEGVLVVHEHGHPHVLMLQIAPGDALKPGE--DEVEGLKARLNHKLAPWEVGELLAVWWRPNFETF-MYPYIPAHITKPKEMKKVYLVHLPDKLLSVPKNMKLLAVPLFELYDNAARYGPQLSALPHLLSRF---------- Sporo1 ------L-PDYSFATKEPQVEEDASVARLQRLEDDFEKHGM-RRTVEGLLIVHEHGHPHVLLLQVAPGDYLKPGE--GDIDGLKKRMQKRLGPWEIADAVGQFYRPNFEGF-MYPYIPAHISNPKELKTWYLVQLPQSVLTVPRNMKLIALPLFELYDNAVRYGPQLAAIPHLLSRI---------- Stehi1 TIALYPL-SNFTFSTKESQPEEDPSVARLQRLQNNYEDFGM-RRTVEGILVVHDHGHPHILMLQIAPGDYLKPGE--DEIEGLKRRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFVPAHITKPKECKKLFLVQMPEKVLAVPKNMKLLAIPLFELYDNAARYGPQLSAIPHLLSRY---------- Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr STVVYPL-ESYSLQERSAQTEEDPTAPPVRDLRGEYKRNGM-RTSVYAVILVHRHGHPHVLALSAAPGGVLKPGE--DERDGLKRVLEARIGVWEIGELVASWWRPSFASPALYPYLPVHVSKPRECIRLFHVHLPQKTFAIPSNYRLTAVPFFDLFNNQGQYSNLLASVPHLFSRYLAQSAMANAD Treme1 ELKSSPM-QNYTLIEREAQAEEDSSVARMQRLEKQYAETGM-RRSVEGVMVVMEHGFPHVLVLQVAPGGYLDPTE--PDGEGLLARMNEQLGVWTVGECLSIWWRPNFDTF-SYPYLPAHVSFPKECRKLYMVNLPVKTLAIPANMKLIALPVYEFYDNASRWGPQLAGLPYIMSKY---------- Trire2 KVTLYPL-SNYTFGVKETQPEEDPSVARLKRLEEHFNEHGM-RRTCEGILVCHEHNHPHILMLQIAPGDYLRPED--DEVEGFKARLDERLAPWEVGECLAQFWRPNFETF-MYPFIPAHVTRPKECKKFYFIQLPKSVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYPKSKVLA-GD Umbra1 EATLYPL-ANYTFGVKEAQPEEDPSVARLKRLQNDFEEHGM-RRSVEAVLVVHEHNHPHVLMLQIAPGHYIDPGM--TEEEGLKAILNERLGPWEIGECLSTWWRPSFEQY-MYPYVPAHITKPTERKQLFVVHLPPHVLTVPRNMKLLAVPLFELYDNAARYGPQLSAIPHLLSRY---------- Ustma22 TLTLYPV-TAFTFTTKDAQPEEDPSVARLQRLQNNYEDLGM-RRTVEAVLVVHEHGHPHVLMLQIAPGDYLKPGE--DEVEGIKARLDERLGPWEIQDCLAQWWRPNFETF-MYPYAPPHVTKPKECKKLFLV------LAVPKNMKLLAVPLFELYDNSQRYGPQLAAIPHLLSRY---------- Walse1 TINIYPL-QNYTFTQREAQPEEDASVARLQRLQNNYEDFGM-RRTVEGIMVVHEHGHPHILMLQIAPGDYLTPGE--TDEPGLKKRLDDRLAPWEIGDCLAQWWRPNFETF-MYPFIPAHVTKPKECKKMYVVGLPERVFAVPRNMKLLAIPVFELYDNSGRYGPQLAAIPHLLSRY---------- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2721.fasta_al_trimmed; alignment length = 361] Allma1 --------MGKLYARIFYINVCDLPDKYDALLNVLENGHLVSRRSDFIIYSVEAKFIDQVVKQYGPSTKVGAIVGGQTSVKAPEIKAFEAYLPPDVQIVTCHSMHGPSVSPKGQPLILIRHRAT-DAERILGTTGSSLVY-LTAADHDRITADTQAATHLAFKAMGTAWYVGGIDNVKVAMTLRIYSNKWHVYGGLALLNPAARVQIQQYAKSVEELFSLMIEFRARVLKGRAYVFALLLADTLLDQYTLSPNSHLSLLAMVDCWYQLQLNPYHHL-ICQTPPFRLWLGITEFLFRNLEQAIQAALRSDDLAFVAAASGWAQTILQGHFDSYQARFEATQAFFKDQLDAGRKLSAQIIETV Ashgo11 IGIIGMGAMGQLYAERFSVLCCDRSERYAELLTILQNGYLVSRECDYIIYSVEAANIGAIVAQYGPSTKLGAIVGGQTSCKSGELQAFEQHLPADVDIVTVHSLHGPKVDPEGQPLVLIDHRTSRPVEALMSCLRSRHVY-ITGEEHDQITADTQAITHAAFLSMGLAWWCGGLENAKMNISLRIYSNKWHVYAGLAITNPTAHCHVTVYAQSATDLFTLMITLRDRLLAAKAAVFRLLLDDAMLDRFSLSPNSHLSLLAIVDSWHRLGIDPYDHM-LCSTPLFRIFLGVSEYLFLALERTIAHAVRADDLEFVAAARSWSQLISFGNFDLYRRQFEEVQRFFEPMFPDATRIGNAMIRTI Aspfu1 IGIIGLGDMGKMYAQQLSVNACDLPQNYERLVTILPNGHLVSRISDYIIYSVEAAVIDRVVAQYGPSTKVGAIVGGQTSCKAPELAAFEKHLPPDVEILSCHSLHGPQVNPKGQPLVLIQHRAS-DVEEVFSSFGSKYVY-LTGEMHDRITADTQAVTHAAFLSMGTAWWVGGIENVKINITLRIYSNKWHVYAGLAILNPAAKEQIRTYAQSVTELYKLMIELKRRVKAAGAAVFKLLLKDEVLDRFSLSPNNHLSLLAIVDCWSKLGIVPYDHM-ICSTPLFRLWLGVTEYLFRNLDEALDTAIRSDDLEFTFAARAWSDCVSFGDFESYRDRFERIQQYFAPRFPEAVKLGNEMMKTI Aurde31 IGLIGMGEMGRMYAHRLSIHVCDLPQNAEKLVTAHVDGHGVARIADVLLYNVEAEHIARVVAQFGPSTRVGAIVGGQTSVKAPERDAFEKYLPEDTHIVSVHSLHGPTVNPEGQPLVIITHRAP-DVEAILTPLRSRHIR-LTYDEHDLVTANTQAVTHAAFLSMGTAWFVGGIETVKVNIAIRIYSNKWHVYAGLAILNPIARSQIAQFARSSTELFQLMIALRERVHRARHAVFG-LLQEDVLDQFQLGENSHLSLLAMVDCWAALNINPFAHLAVAATPIFRLWIGIAQTLFLNLERAIVAAVRANDLEFVVAARGWAQCVAHGSFELYERRFAETAQFFEPRFEEATRVGGSMIRAV Batde5 --------MGKLYARTFIVFACDVPERYSDLIHILKDGFAVVRQCDFVIFSVEAMSIRTVVSKFGPAMKVGSIACGQTSVKTPEIAAFQEFLPQDVQIVTCHSLHGPSVNPKGQPLVVIRHRSD-QAIKILKTLQSDMVY-LTAAEHDRITADTQAVTHVAFLSMGTAWYVGGIENVKVLMALRIYSSKWHVYSGLALMNPNVMPQAQQYSQSVSDLFKLMIELTTRIKNARDFVFGILLSDSVLDQFSLSSNSHLSLLAMVDCWAQLKIKPYEHL-ICQTPPFRLLLGIAEFLFRDLNESIQSAIRSDDCEFYTSTKGWVECIGLGSPDAYRQRFECTAAFFSDRTTQARKVSAQLVEMI Botbo1 IGLIGMGAMGMMYAQRLSIHVCDRPEKYEDLVVVYRDGHGVSRSSDFILYSVEAEFIDRVVAEYGPSTKVGAIVGGQTSVKAPEKEAFEKYLPEDVHIVSCHSLHAPSVNPQDQPLVLIKHRAA-NVENILRPFRSRYVY-MTYEVHDLVTANTQAVTHAAFLSMGTAWYVGGIETVKVNIMLRIYANKWHVYAGLAILNPQARPQIDQFAKSATELYKLMLELRRRIYAARDAVFGIFLSEAVLDQFSLGANSHLSILAMVDCWAVLHIRPFAHLELAATPVFRMWIGIAEYLFRSLDAAIAAALRSDDLEFVIAARGWSQCVSFGSFELYADRFQHTAAFFEARFDEAVAVGSRMIKTI Botci1 IGIIGMGDMGKI------VNACDREDKYEALITILPNGHLVSRASDYTIYNVEAASIGKVVAEYGPSTKQGAIVGGQTSCKAPEIAAFEKYLPADVDIVSCHSLHGPNVDPRGQPLVLIKHRAS-QVEYVLSCLGSKQHV-LSASQHDRITADTQAVTHAAFLSMGKAWYVGGIENVKINLTLRIYSQKWHVYAGLAILNPYAKEQIREYASSVTDLYKLMLELDERIKSAGRFVFALLLRDEVLDRFSLGPNNHLSLLAIVDCWARLNISPYDHM-ICSTPLFRLWLGVSEYLFRNLEEVINTAIRSDDLEFTFAARGWSECVEFGDFESWKDRFEKTQMFFAPRFPEATRVGNEMMKTI Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 IGIIGLGDMGYLYAKRFSVVGCDREDLYETTFEILRNGHFVSRISDYIIYSVEAENIEKIVSIYGPSTKFGAIVGGQTSCKAPEIAAFEKHLPEDNEIISLHSLHGPKVNTTGQPLVLIKHRAT-DVEALVSCLNSKQVY-LTAKEHDRITADTQAVTHAAFLSMGVAWWIGGIENAKINISLRIFSNKWHVYAGLAITNPSAHDQVLQYSKSTTELFTLMIELTERLTKAKQFVFKLLLDDNILQKFSLSPNSHLSLLAIVDSWYNLGIVPYDHI-ICSTPLFRIFLGVTEYVFCTLEESIDVAVRQDDLNFTIAAQTWSNIISFGNFELYKREFEDTQNFFQPMFQEANAIGNEMIKTI Cangl IGIIGLGDMGLLYATKFSVVACDREELFDSLFDIVKNGHYVSRISDYIIYSVEAENIDKLVKLYGPSTKVGAIVGGQTSCKTPEIKAFEKYLPEDVEIITLHSLHGPKVNTEGQPLVLINHRSKTDIESLVSCLKSKQVY-LTYEEHDRITADTQAVTHAAFLSMGRAWWYGGLENVKVNISLRIYSNKWHVYAGLALTNPMAHKQILQYATSATELFTLFLELTERLNKAKEFVFGLLLDDTIFEKYSLSPNSHLSLLAIVDSWHQLGINPYDHM-ICSTPLFRIFLGVSEFLFLSLEKTIDAAIRRDDLEFVVAAREWSSIVTFGNFDLYKRQFEDVQKFFEPMLPEANQIGNEMIKTI Capow VGIIGMGEMGRLYADWISVHCCDVPERYDELVRVHRDGFAVVRQCGLVMYSVETANMDRVVGLYGPATRVGAIVAGQTSVKAPEIAAFERHLPSDAHIVTCHSLHGPRVSPRGQTMVVIRHRCDKDALAVFRRLESNMVE-MSAETHDRITANTQVISHLGFQAMGTAWYLGGIDNVKILMCLRIFAAKPHIYSGLAMQNPQARYHVEQYVRSVSELFRLMIEFTARIYAARAAVFGLLLPDAILAEYGLGPNSHLSLLAMVDAWYAMKVNPYDDL-VCQTPVFRLRLGIAEYLFCDLDESIAAALRGDDMEFFAAVREWATIILNGDLRGYEDHFLRVRQFFESRLQDGFKASCVLIDRL Catan2 IGIIGMGDMGRLYARHFAINVCDLPEKFEQLYNVLANGHLASRRSDWIIYSVEAKFIDAVVKQFGPSTKVGAIVSGQTSVKAPEIQAFESHLPSDTHLIPIHSMHGPNVSPAGQPLVIIPHRST-PVESILASLSSQIVH-LSAADHDRITADTQAVTHLAFKSMGTAWYVGGIDNVKVAMTLRIYSNKWHVYAGLALLNPAARRQIKQYARSVNELFSLMIEFKARVRAACDYVFGVLLADALLDEYTLSPNSHLSLLAMIDCWHTLSIQPYKHL-IVQTPPFRLWLGIVEYLVKTLDAAMDAALRADDLAFVAAAAGWAQTIDMGHFDSYQHRFEETQKFFEARLLEGKKVSASIIEKV Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ----------------------------------MQNGHLVSRCSDFIIYSVEAKNIDAVVKAFGPSTKVGAIVGGQTSCKTPEMDAFNKHLPKDVSIVSVHSLHGPGIDPKGQPLVLIKYRAS-DVENIMSCLGSKHVY-LSAEQHDRITADTQAVTHAAFLSMGGAWYVGGIENVKMNITLRIYSNKWHVYAGLAILNPDAKRQIKQYAESVTELFKLMLELRERVHAARKAVFGLLLRDDLLDQFALGKNNHLSLLAMVDCWWKLGIVPYDHM-ICSTPPSRMWLGITEYLFCNLEEAIETAIRADDLEFTFAARDWSSRITLGNFDGYRDKFEQIQKYFEPRFPEATKLGNEMIKVI Coere1 IGIIGAGDMGMLYAKRFRVNLCDTPEKYDELISILRDGYAVSRRSDIIIYSVPAVIINKAVAEYGRATKMGAIVAGQTSVKTPEVLAFEKHLPEDVHIVTCHSMHGPNIDTKGQPLAVIRYRSD-DAVKVLGALESRMIF-LTYEEHDRLTADTQAATHLAFISLGTAWFISGINNVKVAMALRIYASKWHVYAGLAIMNPLARKQLQCYVVSMTTLYKYMIEFRDLVYRSADFIFGILLDDDVLEQLSLSPNSHLSLLCAAVCWYKMNMSPYDSL-VCQTPPFRMWLGIVEYLFCSLEESIETALQSEDLVFYTAVTGWGQCIELGSFEGYQERFEATAEFLRPKLEEGKDLSTMILKKL Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 IGLIGMGAMGEMYAKYLSINVCDLPSKYESLITVLQDGHAVARVSEFIMFSVEAEHIDKVVAQYGPSCKVGAIVAGQTSVKAPEKDAFEKYLPLDTHIVSLHSLHGPTVSPVGQPLVIIKHRAP-DVENILKCFRSRFVY-LTYEDHDLVTANVQAVTHAAFLTMGTAWYVGGIETVKVNIMHRIYANKWHVYAGLAILNPSAKVQIDQYASSATELFKLMLGLRARVFEARERVFGIFLTEDVLDQFTIGSNSHLSLLAMVDCWAKLGIHPFVHLDLAATPIFRMWIGVAEYLFRSLDAAVRAALRSDDLEFVVGARGWSQCVSFGNFELYRRRFAETAAFFEPQFDEANTIGGAMIKAI Copci IGLIGMGAMGRMYAKYLAIHVCDLPERFEKLIHPMRDGHAVSRSSDFIVYSVEAEYIDRVVAEYGPSTKMNAIVAGQTSVKAPERQAFEAHLPQDVHIVSCHSLHGPGVSPVGQPLVLIKHRGT-DVESILSPLKSRFVY-LSYEEHDSVTANTQAVTHAAFLSMGTAWYVGGIETVKVNLTLRIFSNAWHVYAGLAILNPSARVQIDQYAKSTSDLFKLMLEFRERIQWARETVFGILLSASILDRFSL-PNSHLSLLAMVDCWAHLGINPYHHLSVAATPLFRLFLGVAEHLFLSLNSAMDSALRSDDLEFVVAARGWSQCVSFGSFDLYRRRFEETRTFFEARFDEAGKLGSEMIKAV Croqu1 IGLIGMGDMGRMYANRLALLICDRPERFESLITVMQNGHLVSRASDFIIYSVDAEFLDGVVEQYGPSTKTGAIVAAQTSVKTPERIAFEKYLPSDVKICSVHSLHGPSISPDGEALVLVPHRCT-NVKRLLSPMKSRYVE-LSYDEHDEVTANTQACTHAAFLSMGTAWYIRGIEVVKINIALRIYSAKWHVYAGLAILNPSAKIQIDQYARSVTELFTLMILLRKRVLIARDFVFGLFPSDDFFKSFAIGPNSHLTLLGIVDCWYQLKINPLKHLELAATPVFKMWFGLIQFLFLNLESTISASIRGDDCEFVLAARGWSQCISHGDFQVYRRRFEHTAEFFSPMFEEGKGKISEMLKFA CryneH991 VGIIGMGDMGRMYAKRLHIYVCDKPDCFDALIHVLRDGHAVSRLSTFIIYSVEAAALPAVVKEYGPSTRVGAVVAGQTSVKAPEREAFEKWLPEDVGITSVHSLHGPSVTTEGQPLIIIHHRGP-EVENVFRSFKSRYVY-LSYEEHDKVTANTQAVTHAAFLSMGTAWYVSGIEVIKVNITLRIYSAKWHVYAGLALLNPSAKSQIQQYATSATELFKLMVELEDRIWGAREEVFGILLSEDVLDQFSLGPNSHLSLLAMVDCWAKLGIRPYEHLDVAGTPVFMLWIGVAEYLFRSLSAALRAALRPDDVEFVVAARGWSECVDVGNFGWYRRRFEETSNFFAPRFDEATKLGGKMIKAI Crypa2 VGIIGMGDMGKMYARRLSIKACDRDEKYDSLIHIVRNGHLVSRESDYIIYSVEAAVIRHVVKEFGPSTKMNAIVGGQTSCKAPEIAALEEHLPPDVDIIPCHSLHGPNVDPKGQPLVLIKHRAS-DVETVLSCLNSKHVY-LSAREHDRITADTQAVTHAAFLSMGKAWYVGGIENVKINLTMRIYSARWHVYAGLAILNPEARKQITQYARSTTELYKLMLGLRRRVYAARERVFGTLLRDEILDRFSLGPNNHLSLLAMVDCWSALGIVPYDHM-ICSTPLFRLWLGVTENLFRHLDEALNTAVRSDDLEFTFAARGWAECVSLGHFDTWRERFRETQTFFEPRFTEANKIGNAMIKAV Debha1 IGIIGLGDMGYLYARRFSVVGCDREDLFEETFEILLNGHYVSRISDYIIYSVEAENINKIVSLYGQSTKFGATVGGQTSCKQPEIEAFEKNLPPDTEIVSLHSLHGPNVNTTGQPLVLIRHRAS-DVECLVSCLRSKVVY-LSAEKHDKITADTQAVTHAAFLSMGVAWWVGGMENAKMNISLRIFSNKWHVYAGLAITNPSAHEQIVQYSRSVTELYTLMIELKARVFKAKESVFRLLLDDDILQNFSLSANSHLSLLSIVDSWFKLDIVPYDHI-ICSTPLFRIFLGVTEYLFCTLDECIQDAVRQDDLEFTIAARTWASIISFENFKLYKKEFEETQAFFQPMLQEANAVGNEMIKTI Dekbr2 VGIIGLGVMGLMYAERFSVVGCDRDENYEQFFEVVKNGHYVSRVSDYIIYSVEAANIDRIVSEYGPSTKVGSIVGGQTSCKYPEIAAFEKHLPKDVEIISVHSSHGPNVDPTGQPSVIIQHRAS-DVESIMSCLHSKHVH-LSYQEHDKITADTQAVTHAAFLSMGSAWWTGGLENAKINISLRIYSNKYHVYAGLAITNPSAHSQILQYSRSCEELFTSMIELTERVMSAKKNVFGLLLDDDSLQQYSLNPNSQLSLSAIVDSWSSSGIVPYDHI-ICSTPLFRIFLGVTEYLFCTLEECLQVAIRKDDLNFVMASREWAFIVSYGDFKLYKTRFEKVQRYFEHMFPEATKVGNQMIKTI Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 IGLIGMGEMGRMYAHHLSIHVCDRPEKYEQLVTVYRDGHHVARASDFILYSVEAEFVDQVVAHYGPSSKLGSIVAGQTSVKAPEKAAFEKYLPPDVQIVSCHSLHGPTVSPLGQPLVIIRHRAS-DVESILRPLRSRFVY-LSYEDHDLVTANTQAVTHAA---MGTAWYVGGIETVKVNITHRIYANKWHVYAGLAILNPSARVQIDQYAKSATELFKLMLALRSRLFRAREKVF-ILLSEDVLDRFSLGANSHLSLLAMVDCWAALGIQPFVHLALAATPIFRMWIGVAEYLFRSLISAIDAALRADDLEFVVAARGWSQCVRFGNFDLYRQRFERTAEFFRPRFGESARLGTEMIKTI Fusgr1 VGLIGMGDMGKMYAERLS--------------------------SDYIIYSVEAAVIDRVIAQYGPSTKLGAIVGGQTSCKSPEIAAFETHLPSDVDIISCHSLHGPNVDPYNQPLVLIQHRAP-DVETVLSCLKSKFVH-LTAREHDRITADTQAVTHAAFLSMGKAWYVGGIENVKVNLMLRIYSQKWHVYAGLAILNPEAREQISQYARSVTDLYKLMLGFRERVYRARDKVFGPLLEPSILSSFSLGPNNHLSILAMVDCWAALNIAPYDHM-LCSTPLFRLRLGVTEYLFRNLDAAIETAIRSDDLEFTFAARAWAECVNLGHFETWEKRFVSTQEFFQPRFEEAKVVGNQMMKKI Galma1 IGLIGMGAMGRMYAKFLGINVCDLPEKYEQLVHPMRDGHAVARSSDFIVYSVEAEFIEDVVEQFGPSTKMHAVVAGQTSVKAPERAAFEKFLPSDVHIVSCHSLHGPTVHPLGQPLVIIQHRGS-NVENILRPLKSRHVY-LSYDEHDLVTANTQAVTHAAFLSMGTAWYVGGIETAKVNLTLRIYSNAWHVYAGLAILNPAARVQIDRYAASATELFKLMLRFRERVEWGRRIVFGILLSEDVLDRFSLGPNSHLSLLAMVDCWAHLAINPYTHLSLAATPLFRLFLGVAEHLFLSLSASIHSALRGDDLEFVCAARGWSQCVSFRSFEVYRKRFEETRAFFEGRFGEAGRVGAEMIQAV Ganpr1 IGIVGFGDMGRLYANRFFVHVCDIPSKYEAILHVHRDGYGVVRISDVVFYSVEAKGIERVVAQFGPAHKPGAVVSGQTSVKEPEVAAFDRHIPDDVDVVPSHSMHGPNVSPLHQPLVLIRHRVRDPVKAILSCLESDFVEGLSYVDHDEITADTQAATHLAFLSMGIAWYMGGIENVKVLLTMRIFSSKWHVYAGLAMMNPAAKVQVREYARSASELFKLMIEFRARIQKAGSTLFPILLSDSFLDEFSLSPNSHLSLLAMADCWYRLNINPYRHL-ICQTPIFRFLLGITEYLFRNLQDAVNHAVRADDFEFCSAARGWVEVVESNNMEAYQSRWEGATAFFGERLREANKVSGQLIAKL Gloin1 IGIIGLGDMGLMYAKRIIVNVCDRSENYEELMNVCQNGHAVSRKSDFIIYSVEAENIDKVVAEYGPSTKLDAIVAGQTSVKEPEIRAFEKHLPDDVHIISCHSLHGPTVDPKGQPLVMIQHRAA-DAMRVLSCMESEFVK-LSYKEHDRITADTQAVTHLAFLSMGTAWYVGGIENVKVHMALRIYSNKWHVYAGLAIMNPSAKLQIQQYAQSVSDLFKLMIEFRTRVKKAGEFVFGILLSDTLLDKFSLSPNSHLSLLAMTDCWYTLEINPYEHM-VCQTPLFRLWTGITEYLFRNLEAAIHSALRADDMEFYSASKGWAECVDIGNMQTYQKRFEDTAKFFESRFDESNKIGREMIKVI Hisca1 IGIIGMGDMGKMYAQRLSVNACDRPTNYDAL--------------------------------------VGAIVGGQTSCKAPELAAFDKYLPDDVEIISCHSLHGPNVNPKGHPLVLIQHRAS-DVERIFSTFQSKYVY-LSGDLHDRITADTQAVTHAAFLSMGTAWYVGGIENVKINITLRIYANKWHVYAGLAILNPAAKKQIRQYAQSVTDLFKLMLELRARVKTAGAAVFKLLLRDDVLDRFSLSPNNHLSLLAIVDCWWKLGIVPYDHM-ICSTPLFRLWLGVTEYLFRNLNEVLDIAIRSDDLEFTFAARAWSECVSFGDFASYRDRFEKIQSYFSPRFPEAVRLGNEMMKTI Klula1 IGIIGLGDMGLLYATRFSVICCDRPEFYEELFNVVENGTLVSRASDYIIYSVEAENIENIVKMYGAASKVGSIVGGQTSCKNAEINAFEKYLPSDCEIVSVHSLHGPKVNTEGQPLVLINHRTKSQVESLMSCLKSQHVY-LSYEEHDKITADTQAVTHAAFLSMGVAWWHGSLENVKVNISLRIYSNKWHVYAGLALTNPAAHKQITQYAKSATELFTLFVELTKRLQVAKDFVFGLLLHDLALDDYSLSPNSHLSLLAIVDSWYQLGIDPYDHM-ICSTPLFRIFLGVSEYLFLTLEQTIDAAIRADDMEFVIAARSWSNIVSFGNFELYKRQFEEVQQFFTPMFPEANAIGNEMIKTI Lacbi2 IGLIGMGAMGKMYADILDIHVCDLPEKYDALISVLQDGHAVARSSDFIIYSVEAEFIDRVVAQFGPSTKVHAIVAGQTSVKAPEKAAFEKYLPKDVHIVSCHSLHGPSVSPQGQPLVLIKHRAS-DVETILSPLKSRFVY-LSYDEHDLVTANTQAVTHAAFLSMGTAWYVGGIETAKVNLALRIYSNAWHVYAGLAILNPSARIQIDQYASSATELFKLMIVFRERVMWAKSVVFGILLSADVLDRFSLAPNSHLSLLAMVDCWAHLRINPYHHLSVAATPIFRLFLGVAEHLFLSLNQAIHSSLRADDLEFVVAARGWSQCVSFGSFEVYKRRFDETRGFFEARFEEAGRLGGEMIKAL Lenti61 IGLIGMGAMGSLYARCFSIYICDLPAKYDALIHVVKDGHLVSRVSDYIVYSVEAEYIDRVVAEFGPSTKVGAIVAGQTSVKAPEKAAFEKYLPEDVQIVSCHSLHGPTVSTAGQPLVIIRHRAT-DVEQILAPLRSRYVY-LSYEDHDTVTANTQAVTHAAFLSMGTAWYVGGIETVKVNIMLRIYSNKWHVYAGLAILNPSARVQIDQYARSTTEIFKLMLGLRARIYDARAKVFGILLSEDILDHFSLGPNSHLSLLAMVDCWARLGIKPFEHLDLAATPIFRMWIGVAEYLFRSLDSAIHAALRSDDLEFCVAARGWSQCISFGSFELYKQRFMHTARFFESRFEEATKVGSAMIEAL Malgl1 VGIIGMGDMGRLYATRLRVNVCDRPEKYESLLTVLRDGHHVSRRSDFLMYSVEAGNIHKVVAEYGPSTKVGAVVSGQTSVKAPERVAFETFLPEDVYIVSCHSLHGPHVDPRGQPLILIQHRAP-AVERILACLESRYVY-MSYEEHDTVTANTQAVTHAAFLTMGTAWNPGGMETVKIYLCLRIYGAKWHVYAGLALLNPEASVQVTQYAASATALFQLMLALVQRVLSARRSVFGILVSDEMLDEFYVIANSHLSLLAIVDCWHVLGIDPYRHLELAATPVFRMWIGVTQNLFRSVLAACRAAVRADDLEFVIAARGWAQAVQFGDFDAYQRRFETTRAFFMPRLSEANKVGVNMLSVL Mellp23 IGLIGMGDMGRMYADRLSLLVCDRAERYESLVEVMKNGHLVSRAADFIIYSVDAEFLESVVAQYGPSTKPGAIVAGQTSVKAPERAAFEKCLPPDVKICSVHSLHGPSISPDGEALILVPHRCS-DVKHVLAPMRSRYVE-LTYEEHDEVTANTQACTHAAFLSMGTAWYVRGIEVAKINIALRIYSAKWHVYAGLAILNPAAKRMIDQYARSVTELFTMMIELKTRILSARDYVFGIFPSDEFFSDFAVGPNSHLTLLGIVDCWHQLKINPFDHLDLAATPVFRMWFGLIQFLFQSLEATISASIRSDDCEFVLAARGWSQCISYGDFGLYRQRFEHTAEFFSPMFEEGKGKIGEMMKYA Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LGIIGMGDMGKLYARTLSVNVCDMPNKYEALIRVMKDGHLVSRQSDWILYSVPAEFIDSVVATYGPSTKIGAIVAGQTSVKAPEIAAFEKHLPEDVYIITCHSMHGPTVSSKGQPLVIINHRGA-AVERILSCFESEIAH-LSYKEHDRITADTQAVTHMAFLSMGTTWYTGGIENVKVNMTMRILSNKWHVYAGLAILNPSAKAQVKQYSLSVAALFKLMIEFVARIRAAGEFVFGILLSDNLLDQYSLGPNSHLSLLAMVDCWYQLKMNPYSHM-VCQTPLFRFWLGISEYLFLNLQDAMQAALREDDMEFMMSARGWQECIALGNMEGYRVRFEDTAQFFKSRFGEAAVIGKQMIEMI Mucci2 LGIIGAGGMGRFYAQTMSVSICDLPEKYESVIHVLPDGYHISRRCDWIMYAVEAEYIDAVVKKYGPATKMGAIVGGQTSVKKPEVEALEKYLPEDVHIISCHSMHGPGVDPKGQPLIVIKHRAT-DVLKILSCFNSNIAH-LSAEEHDRITADTQAVTHAAFLTMGSAWFTGGIENVKVNVALRIYSNKWHVYAGLAIMNPIANQQITQYALSVADLFKLMIEFRARVKKAGEFVFGILLDDKILDEFSLSPNSHLSLLAMVDCWHRLGLNPYEHL-VCQTPLFRMWMGITEYLFRNLDDAINAALRPDDMEFVTCARGWAESVSLGSMEGYRKRFEETAAFFKDQFAESTVVGNRMIAMI Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 -------------------MACDREEKYDELIQILRNGHFVSRASDYIIYSVEAAVIDRVVAQYGPSTKLGAIVGGQTSCKDPEIKAFEKYLPADVDIVSCHSLHGPNVDPKGQPLVLIKHRAS-DVEHVLSCLNSKVVY-LSADEHDRITADTQAVTHAAFLSMGKAWYVGGIENVKINLMLRIYAQKWHVYAGLAILNPEAHKQIAQFAKSTTELFQLMLELRARVYAAKEKVFGPLLRDDVLDQFSL-PNNHLSLLAMVDCWSALGIVPYDHM-ICSTPLFRLWLGVTEHLFRTLDECLKVGIRRDDLQFTIAAAGWAECVGLRQFETWRERFAVTQAFFEPRFKGAVEVGNAMIKAV Orpsp11 -------------------------------IKVWRDGHQVSRISDVIFYSVEAKNIDAVVKEYAPSTKYNAVVGGQTSVKEFEIIAFEKYLPPDVDILSCHSMHGPTVMTKGQPLVLIRHRCN-DVNRILDCLQSQKVM-LSYIEHDQITADTQAVTHVAFLSMGSAWYAGGIENVKVLMTLRIYSNKWHVYAGLAMMNPSAMRQVHQFAKSVNELFKLMVEFVKRIKNAGEQVFSILLEDEILDKFSLSPNSHLSLLAMVDCWNKLNINPYDHM-ICETPIF----------------------------------------------------------------------------- Pench1 ----------MLHPRYLNINACDRPENFESLVTIFPNGHLVSRISDYILYSVEAGVIDKVVAEYGLSTKVGAIVGGQTSCKAPELAAFEKHLPPDVEIVSCHSLHGPKVNPQGQPLVFIQHRAS-DVESILSSFGSKHVH-LTGEMHDRITADTQAVTHAAFLSMGTAWWVGGIENVKINITLRIYSNKWHVYAGLAILNPAAKQQIRQYAESVTDLYKLMIELKRRVKAAGASVFRLLLKDEVLDRFSLSPNSHLSLLAIVDCWSKLGIVPYDHM-ICSTPLFRLWLGVTEYLFRNLDEALDTAIRSDDLEFTFAARAWSDCVSFGDFESYRHRFERIAEYFAPRFPEAATLGNEMMKTI Phybl2 IGIIGAGGMGRFYANKLSINICDLPSKYESLINVLPDGFHVSRRCDWIMYAVEAEYIDSVVSTYGPASKIGAVVGGQTSVKQPEIDALVKYLPSDVHIVSCHSMHGPGVDPKNQPLVVIRQRAT-DVLNILECFESNIVH-LSAEEHDRITADTQAVTHAAFLTMGSAWLVGGIENVKVNVALRIYSNKWHVYAGLAIMNPTAKIQIAQYAKSVADLFKLMIEFRARIKAAGDHVFGILLSDQILDEFSLSPNSHLSLLAMVDCWYALKLNPYDHM-VCQTPLFRLWMGITEYLFRSLEDTIQAALRSDDMEFVTCARGWAECVDLGSMEGYQKRFTATADFFRDRFSDSNIVGNKMIAMI Picst3 IGIIGLGDMGYLYAKRFSVVGCDREDLYEETFKILRNGHFVSRISDYIIYSVEAENIRKIISIYGPSTKFGAIVGGQTSCKEPEIAAFEDILPKDVKIISVHSLHGPKVSTTGQPLVLINHRGD-DVECLVSCLNSKIVY-LSAKEHDKITADTQAVTHAAFLSMGVAWWIGGLENAKMNISLRIFSNKWHVYAGLAITNPSAHEQVLQYSSSTTSLFTLMIELRERMLKAKEFVFGLLLDDYILQKFSLSPNSHLSLLAIVDSWFTLGIVPYDHI-ICSTPLFRIFLGVTEYLFCALEECIEDAVRQDDLEFTIAARNWASIISFGNFELYKREFEKTQKFFLSKFSEANVIGNEMIKTI Plicr1 IGLIGMGAMGKMYAKYLSIHVCDQPTKYDALITVHRDGHLVSRTADWIMYSVEAEFIDAVVAQYGPSTKVGAIVAGQTSVKAPERAAFEKYLPEDVHIVSCHSLHGPTVSPLNQPLVLIKHRAP-EVESILRCFRSRYVH-LSYEEHDLVTANTQAVTHAAFLSMGTAWYVGGIETVKVNIMLRIYSNKWHVYAGLAILNPSAREQIDQFSRSATELFKLMLELRTRIYAAREKVFGILLEEDVLDRFSLGANSHLSLLAMVDCWAHLGIKPYVHLALAATPVFRMWIGVAEYLFRALDAALHAALRSDDLEFVVAARGWSQCVAFGNFELYRRRFEATAKFFESRFEEAVKVGSAMIGAI Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 VGLIGMGEMGRMYADRLALLVCDRPEKFDQLVTVVANGHLVSRASDLIIYSVDSEHIEMIVEQYGPSTKLGAIVAAQTSVKAPEQAAFEKHLPSDTRVCSIHSLHGPSIPPDGQALVLIPFRCS-VVKDILAPLRSRYVE-LSYEEHDVVMANTQACTHAAFLSMGTAWYIGGIEVAKINITLRIYSSKWHVYAGLAIMNPIARIQIDQFARSVTELFVLMVGLRKRVHAGRDHVFGMFLSEEVFSNFAIGPNSHLTILAIVDCWHQLGLNPFLHLDIAATPVFRLWFGLIHHLFDSLDKAIHAAVRADDCEFVLAARGWSQCISYGDFKLYQARFQQTAEFFKPRIEEGKDKGSAMMKHI Punst1 IGLIGMGAMGKMYAHFLSIHVCDRPPHYESLITVLPDGHRVSRTSDFIMYSVEAEFIDRVVAEYGPSTKVGAIVSGQTSVKAPEKAAFEKYLPEDVHIVSCHSLHGPTVSPTGQPLVLIKHRAP-DVESILRPLGSRFVY-LSYEDHDLVTANTQAVTHAAFLSMGTAWYVGGIETVKVNIMLRIYSNQWHVYAGLAILNPSARLQIDQYARSVTELFKLMLALRDRVYSARDTVFPILLSEDVLDQFSLGANSHLSLLAMVDCWAHLGIQPFVHLELAATPIFRMWLGVAESLFCSLDGAIHAAVRSDDLEFVVAARGWSQCVSFGSFELYKQRFTQTASFFSTRFEEATKIGSAMLQTI Rhior3 IGIIGAGGMGRFYAQRFSVNICDLPEKYEQLINVLPDGFHISRRCDWIMYAVEAEYIDAVVKRFGPATKIGAIVGGQTSVKKPEIDALEKYLPEDVHIISCHSMHGPAVDPKGQPLIVIKHRAS-DVLRLLSCFDSNIVH-LSAEEHDRITADTQAVTHAAFLSMGSAWFVGGIENVKVNVALRIYSNKWHVYAGLAIMNPIAKDQIMQYAKSVADLFKLMIEFRARIKEAGDSVFGILLDDQLLDEFSLSPNSHLSLLAMVDCWHKLGLNPYEHM-VCQTPLFRLWMGITEYLFRNLEDAIQAALRSDDMEFVTCARGWAESVSLGSMEGYQKRFEQTASFFKDQFAESTAVGNRMIAMI Rhoto1 IGLIGMGEMGKMYAERLSINVCDLPERYDQLLVPLRDGHLVSRESDFIIYSVEAAYVDKVVAQYGPSTKVGAIVSGQTSVKAPERAAFEKHLPADVHIVSIHSLHGPTVPTDGQALIIIQHRAD-NVKEVLAPLNSRYVD-LSYDEHDEVTANTQAVTHAAFLSMGTAWYIGGIEVVKINITLRIYAAKWHVYAGLAILNPTAQKQIHQYAQSASDLFKLMVELRRRVLAARDFVFGILLSDSVLDRFAIGPNSHLALLAMVDCWHQLRIRPFVHLALAATPVFRFWIGVAEYLFRDLEAAIKAAGSSDDAEFVIAARGWSDTVRYGSFEAYKQRFDETRMFFEPRFEESRIANRDMFAFL Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 IGIIGLGDMGLLYANKFTVICCDREEYYDELFELVKNGHLVSRQSDYIIYSVEASNISKIVATYGPSSKVGTIVGGQTSCKLPEIEAFEKYLPKDCDIITVHSLHGPKVNTEGQPLVIINHRSQYPVNSVMACLKSKQVY-LTYEEHDKITADTQAVTHAAFLSMGSAWWYGGLENVKVNISLRIYSNKWHVYAGLAITNPSAHQQILQYATSATELFSLMIELTDRLLKAKQFVFGLLLDDTILEKYSLSPNSHLSLLAIVDSWFQLGIDPYDHM-ICSTPLFRIFLGVSEYLFLKLEQTIDAAIIKDDLEFVISAREWSSVVSFANFDIYKKQFQSVQKFFEPMLPEANLIGNEMIKTI Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MGLIGMGAMGKMYAKFLSIHVCDLPDKYESLINVFPDGHGVARSSDFIIYSVEAEFIDSVVAKFGPSTKLGAIVAGQTSVKAPEKAAFEKHLPPDVEIVSCHSLHGPTVSPADQPLVLIKHRAS-DVENILRPLRSRYVY-LSYEEHDSVTANTQAVTHAAFLSMGTAWYVGGIETAKVNITLRIYSNLWHVYAGLAILNPAARAQIEQYARSASDLFKLMV-FRARVRWAQQVVFGILLSQALLDKFSL-PNSHLALIAMVDCWAHCGIQPFTHLALAATPIFRLFLGVAEHLFLNLEQAIHSALRPDDIEFIIAARGWSQCVSFGSFEIYRRRFEETRAFFEGRFDEANVLGSQMIKAI Schpo1 VGIIGFGDMGRLYAEYISVNVCDRPENYESIYTVLKDGFQVSRTSDYILYSVEAEHIDKVVALYGPATKVGAIVGGQTSCKAPEMNAFEKYLPEDVDIISCHSMHGPKVNPKSQPLVIIRHRAS-DVNEILSCFKSSVVY-LSAKEHDRITADTQAVTHAAFLTMGLAWWCGGIENIKMNLSMRIYSSKWHVYAGLAILNPEAQRQIQQYASSVTELFKLAIEYEDRIRNAGKFVFGLLLSDELLDQYSISRNSHLSILAIVDSWSKLGIHPQNHM-ICSTPLFRLWVGVSEYVFRHLDSCIYTATSPDDLEFVVAVRSWSECVAAKDFTTYKKRFLETQEYFRPRFEEATRVGNAMISKL Sorma VGLIGMGDMGKM------IMACDREEKYDELIQILRNGYLVSRASDYIIYSVEAAVIDRVVAQYGPSTKLGAIVGGQTSCKDPEIKAFEKYLPADVDIVSCHSLHGPNVDPKGQPLVLIKHRAS-DIEQVLSCLKSKVVY-LSAEEHDRITADTQAVTHAAFLSMGKAWYVGGIENVKINLMLRIYAQKWHVYAGLAILNPEAHKQIAQFAKSTTELFYLMLELRARVYVAKEKVFGPLLRDDVLDQFSL-PNNHLSLLAMVDCWSALGIVPYDHM-ICSTPLFRLWLGVTEHLFRTLDECLKVGIRRDDLQFTIAAAGWAECVGLRQFETWRERFAVTQAFFEPRFKGAVEVGNAMIKAV Sphar VGIIGLGDMGILYAKLFAVVACDREERYAELLEVVKDGFGVARLADLLIFSVETRVVDAVVKQYGPAVKYGCIVAGQTSVKGPEIDAFDKYLPSDVNVVTCHSLHGPGVSPVGQTMVVMRHRA-SDAVSTYKMLGSKLVF-MSCEEHDKVTADTQVATHLGFLAMGTAWFLGGVDNVKILMALRIYSMKSHVYSGLALLNKHAKRQALQYSKSVTALLQYMIAFAKRIHEAGDAVF-LLLSDEVLGEYGLGPNSHLSIIAMVDCWHQLGVNPYNNL-ACQTPVFRLRLGIAQYLFKDLDESIRCAVRADDMEFHAAVREWVTIICKGDESAYEQQFNETRSFFEDKLVEGREASSRLISKL Spipu1 VGIIGLGDMGRLYGLSFLVNVCDIPSRYEQLLNVLPDGYSVSRRSDFIVYSVEAANIDRVVGMYGPGTKLGATVCGQTSVKEPEIRAFEKYLPPDVNIVTCHSMHGPRVNPKNQPLVVIRHRSD-QAVRILNSLQSDIVY-LNYLDHDRITADTQVATHLAFLSMGTAWYVGGIENVKTLMTLRIYSNKWHVYAGLAILNPSARPQVRQYANSVSELFKLMIEFRKRVKAAAAFVFGLLLSDDVLDQFSLSPNSHLSLLAVVDCWHALEPSPYDHL-ICQTPPFRMLLGLTEYLFLELDDAINAALRSDDCEFYTATRGWVECIELGSMEGYEKRFTETAAFFEDRLVQGAKASAKLIETL Sporo1 IGLIGMGEMGKMYAERLSINVCDLPEKYDSLLVPMRDGHHVSRESDFIIYSVEAAFLDKVVAQYGPSTKVGSIVSGQTSVKAPERAAFEKYLPKDVNIVSIHSLHGPTVPPDGQALIIIKHRAS-TVQDLLAPLKSRYVH-LSYDEHDEVTANTQAVTHAAFLSMGTAWYIGGIEVVKINIALRIYAAKWHVYAGLAILNPTAQKQIHQFSESATDLFKLMIELRKRVFDARDFVF-ILLSDKALDRFSIGPNSHLALLAMVDSWHLLKIRPFVHLQLAATPVFRFWIGVAEYLFRDLEAAVEAATSADDAEFVIAARGWSDTVRYGSFEAYRKRFEETRVFFEPRFE------------- Stehi1 IGLIGMGAMGKLYAKCLSIHVCDRPDLFEDLVKVLRDGHHVSRTSDFIVYSVEAEYIDRVAAEYGPSTKVGAIVAGQTSVKAPERAAFEKHLPEDVHIVSCHSLHGPTVNPRDQPLVLIKHRGT-DVESILKPLQSRYVY-MSYEEHDLVTANTQAVTHAAFLSMGTAWYVGGIETVKVNIMLRIFSNKWHVYAGLAILNPSARIQIKQFAQSTTDIFKLMLGLRERMYDARRKVFGILLSEDILDEFSLGSNSHLSLLAMVDCWARLSINPFHHLDLAATPVFRMWIGVAEYLFRSLDAAIHAALRYDDVEFVVASRGWSQCVSFGSFELYRQRFEETAKFFEPRFEEAGKVGSEMLKVI Tapde11 IGIIGMGDMGKMYAKRLSINACDVLSKYDGLINILSDGHYVSRRSDYIIYSVEAEHIERIVSQYGPSTKMGAVVGGQTSCKAPEMSAFEKYLPADVDIISCHSLHGPGVNPAGQPLVIIRHRAS-DVKSVLRTFESKIVE-LSAAEHDRITADTQAVTHAAFLSMGVAWWVGGIENVKINIALRILSNKWHVYAGLAILNPAAHKQIKQYAASVTELYKLILQFEARIRAAGDAVFGLLLQDDVLDRFSLSPNSHLSLLGMVDCWHKMGIVPYDHM-ICSTPLFRLWLGVTEYLFRQLTETINAALRSDDLEFTIAARGWSDIVNYKDFQSYKKRFENVQAYFEPRFVEATALGNEMIRTI Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 VGIIGMGDMGKMYAKRLKIYVCDKPDRFSELITPLSDGHAVSRLSDLIIYSVEAAAISAVVKEYGPSTKFGATVAGQTSVKAPEKEAFEQYLPEDVDIVSVHSLHGPSVTTEGQPLIIIHHRGP-EVENIFKSFKSRYVH-LSYEEHDLVTANTQAVTHAAFLSMGTAWYVSGIEVVKVNIMLRIYSAKWHVYAGLALLNPSAQVQIKQYALSTSDLFKLMVELSSRVWEAREGVFGILLSEDILDQFTLGPNSHLSLLAMVDCWNKLGIRPFEHLEVAGTPVFMLWIGVAEYLFRSLQAAIDAGLRPDDLEFVIAARGWSECVSFGNFDLYQRRFEETSSFFAPRFEDATKLGGRMIKAI Trire2 VGLIGMGDMGRMYAEKLSILACDREDRYDSLIEILRNGHLVSRASDYIIYSVEAAFIDRVIAQYGPSTKMGAIVGGQTSCKSPEIAAFEAHLPSDVFIVSIHSLHGPGVDPQNQPLVLIQHRAP-DVETVLSCLKSKYVH-LTAKEHDRITADTQAVTHAAFLSMGKAWYVGGIENVKMNIMLRIYSQKWHVYAGLAILNPEARQQVAQYARSVTELYKLMLGLTARIYAAREKVFGPLLEPSILSSFSLGPNNHLSLLAMVDCWAALAIVPYDHM-LCSTPLFRLRLGVTEHLFRNLDEALRTAVRSDDLEFTFAARGWAECVTLGHFETWEKRFVSTQEFFQPRFADAKKVGDEMMKKV Umbra1 LGIIGMGDMGRMYASKLSIYVCDQPSNYEKLINVMRDGYHVSRLADWIMYAVEAEHIDRVVAQYGPATKIGSIVSGQTSVKQPEIEAFERHLPEDVHIISCHSMHGPNVNPKGQPLVIIKHRAT-QVRNILSGFESNFVE-LSYQDHDRITADTQAVTHAAFLSMGAAWFVGGIENVKVNVALRIYSNKWHVYAGLAIMNPSARIQITQYARSVADLFKLMIEFRARIMKAGDYVFGILLDDKLLDEFSLSTNSHLSLLAMVDCWYTLKLNPYEHM-VCQTPLFRLWMGITEYLFRKLEETIQAALRSDDMEFVTCARGWAECVELGSMDGYRTRFESTADFFKDMFADSAVLGNKMIAMI Ustma22 IGIIGMGDMGRLYATKMRVNVCDRPENHEKLLNVLRDGHLVSRRSDFIIYSVEAAFIDKVVEQYGSSTKIGSIVAGQTSVKAPEKAAFEKHLPQDTYIISCHSMHGPKIDPTGQPLILIQHRAP-DVERIMACFKSNFVY-LTYEEHDTVTANTQAVTHAAFLSMGTAWYPGGIETVKINICLRIYSAKWHVYAGLALLNPAAKTQVTQFAQSCTDLFKLMVQLMDRVFAARKKVFGILMSDKLLDRFHMAPNSHLSLLAIVDCWSSLGINPYDHLDLAATPIFRIWIGVCEYLFRSLRQACHAAARADDTEFVIASRGWAQAVQFGNFDSYQRRFEETRGFFEHRFQEAGAVGAEMLKVV Walse1 IGIIGMGDMGKMYARNFSV-VCDREENYNTLVEVVKNGHLVSRKADFIIYSVEAAFIDKVVAEYGSSTKVGATVSGQTSVKAPERAAFEKHLPKDVHVVSVHSLHGPTVSPEGQPLVLIQHNSP-DTEQVFDCFRSRYVY-LTYEEHDIVTANTQAVTHAAFLSMGTAWYVNGIEVVKCNIALRIYANKWHVYAGLAILNPSAHAQVRQFATSATDLFKLMVSLKQRALEARRAVFGILLSDTLLDRFSLHRNSHLTILTMVDCWHKLGIHPFDHLDVAGTPLFRMWIGVAEYLFRSLNLALESAARADDTEFVVATRGWSEVIEHGSFTHYKEKFESTAKFLEPRFEEANRMNKEMLKVI Zygro1 IGIIGLGDMGLLYAKEFSVVACDKEEHYQALFEIVANGHLVSRVSDFIIYSVEAESIEKIVSLYGPSSKVGAIVGGQTSCKNPEIAAFERHLPLDTEIITVHSLHGPKVSTEGQPLVLIKHRCQHEVQTVMSCLKSKFVY-LDYEEHDKITADTQAVTHAAFLSMGAAWWYGGLENVKVNISLRIYSNKWHVYAGLAITNPAAHQQILQYATSATELFTIMLKLVERLQKAKEFVFGLLLDDKLLDKFSF-PNSHLSLLAIVDSWYQLGINPYDHM-ICSTPLFRVFLGVSEYLFLTFEKTIDAAIRRDDLEFVVSAREWSSIVGFANFELYRKQFEQVQKFFEPMFPKANKVGNEMLKTI [Cluster2722.fasta_al_trimmed; alignment length = 327] Allma1 RSIQTLDFERSDYPPAKLQEVLGK-DTLAVIGYGTQGRAQALNARDNGMKVIVGVREGGHSWKLAQKDGWVPNETLFDIEPACDKGTVVMNLLSDAGQKEAWPAMKKYLTKGKTLYFSHGFGVVFADQTGIVPPKDIDVILAAPKGSGTTVRNLFLEGRGINSSVAVHQDVSGKAKERAVAIGVAVGSGYLYETTFAKEVYSDLTGERGVLMGAIQGMFQAQYEVLRAKGHTPSEAFNETVEEATQSLYPLIGANGMDWMYANCSTTAQRGALDWKPVFEELYKSVETGEETRRTLDVNSYRESLEKELAEIEMWRAGVTVRQLRPE Ashgo11 RGVKQISFERADWPREKLLEYFKN-DTLALIGYGSQGHGQGLNLRDTGLKVVVGVRKGGASWKAAVEDGWVPGENLFDVVEAVERGTIVMNLLSDAAQSETWPTLRPLLTPGKTLYFSHGFSPVFKDLTHVEPPKDIDVILVAPKGSGRTVRSLFLEGRGINSSYAVWNDATGRAHEKAQALAVAVGSGYVYETTFEKEVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHSPSEAFNETVEEATQSLYPLIGKHGMDYMYDACSTTARRGALDWKPVFRDLYESTRNGSETKRSLEFNSYRDKLEAELQTIEIWKVGKEVRKLRPE Aspfu1 RGVKTIAFERADWPREKLQEYFKN-DTLALIGYGSQGHGQGLNLRDQGLNVIVGVRKDGASWKEAIQDGWIPGKNLFDLTEAVQKGTIVMNLLSDAAQSETWPTLKPLITKGKTLYFSHGFSPVFKELTKVDVPKDVDVILVAPKGSGRTVRTLFREGRGINSSIAVYQDVTGKAKEKAIAMGVAVGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYAACSTTARRGAIDWKPIFNELYDSVRDGTETKRSLEYNSYREKYEKEMQDIEIWRAGKAVRSLRPE Aurde31 RGVKTLDFERADWPLPKLQEYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWKQALEDGWVPGETLFPIEEAINKGTIIMNLLSDAAQSMTWPSIEPLITKGKTLYFSHGFSVVYKEQTKVIPPADVDVILVAPKGSGRTVRTLFKEGRGINSSFAVHQDVTGKAKEKATAIGVAIGSGYMYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRANGHSPSEAFNETVEEATQSLFPLIGQHGMDYMYAACSTTARRGALDWLPVFEKLYESVKNGTETGKSLEFNSYREDLARELAEIEIWRAGKTVRSLRPD Batde5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 RGVKTLDFERADWPLPKLQDYFKN-DTLALIGYGSQGHGQGLNLRDNGINVIVGVRKDGESWRQAIEDGWVPGETLFPIEEAINRGTIIMNLLSDAAQSSTWPTIQPLLKPSQTLYFSHGFSVVFAEDTKVIPPKDMDVILVAPKGSGRTVRTLFKEGRGINSSIAVYQDVTGKAQEKAIALGIAVGSGYLYETTFEKEVYSDLYGERGVLMGGIQGMFRAQYEVLRANGHSPSEAFNETVEEATQSLFPLIGQHGMDYMYAACSTTARRGALDWKPVFEALYKSVRDGTETRKSLEWNSYREDLKKELEEIEIWRAGKTVRSLRPD Botci1 RGVKTIDFERADWPVERLQEYFKN-DTMAIIGYGSQGHAQSLNMRDNGLNVVVGVRKNGQSWKDAQQDGWVPGKNLFEVDEAISKGTIIMNLLSDAAQSETWPALKPQITKGKTLYFSHGFSPVFKDQTKVDVPTDVDVILVAPKGSGRTVRTLFREGRGINSSIAVFQDVTGKAQEKAIALGVGVGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLREQGHSPSEAFNETVEEATQSLYPLIGANGMDWMYEACSTTARRGAIDWKPVFNDLYDSVKTGKETQRSLEFNSYREKYEAEMKEIEIWRAGKAVRSLRPE Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 RGVKTINFERADWPKERLLDYFKN-DTFALIGYGSQGYGQGLNLRDNGLNVIIGVRK-GSSWEAAVEDGWVPGENLFEVDEAISRGTIIMDLLSDAAQSETWFHIKPQLTEGKTLYFSHGFSPVFKDLTHVEPPSNIDVILAAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAEEKAIAMAIAIGSGYVYKTTFEREVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHTPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFEELYESVKNGSETKRSLEFNSYKERLEEELQTIEIWRVGKEVRKLRPE Cangl RGIKQINFERADWPREKLLNYFAN-DTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGENLFEVEEAVKKGTYVMNLLSDAAQSETWNSLKPLLTKGKTLYFSHGFSPVFKDLTHVEPPKDIDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVSGKAHEKAQALAVAVGSGYVYQTTFEKEVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFQDLYESTKNGSETKRSLEFNSYREKLESELQTIEIWRVGKEVRKLRPE Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 RSIQTLDFERSDFPKEKLQQILGK-DTLAVIGYGTQGRAQSLNARDNGLKVIVGVRRGGHSWKLAQQDGWIPDQTLFDIDTACGKGTILMNLLSDAGQKDAWPAMKPFLTKGKTLYFSHGFGVVFADQTGIVPPKDVDVILAAPKGSGTTVRNLFLEGRGINSSVAVYQDVSGKAHERAVAMGAAIGSGYMYETTFKKEVLSDLTGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGANGMDWMYANCSTTAQRGALDWSPCLRTCTRAWPRARKRGVPSSATQTARVCKRSWTRLKCGGQARRSGSCGPR Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RGVKTIDFERADWPKEKLLEYFKN-DTLALIGYGSQGHGQGLNMRDNGLNVIVGVRKNGASWKEAEQDGWVPGKNLFDIDEAIGKATIVMNLLSDAAQSETWPAIKPQLTKGKTLYFSHGFSPVFKDLTKVEVPKDIDVILVAPKGSGRTVRTLFREGRGINSSIAVYQDVTGKAKEKAVALGVAVGSGYMYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDYMYAACSTTARRGAIDWKPVFDDLYTSVENGTETKRSLEYNSYREKYKQELKEIEIWRAGKAVRSLRPE Coere1 RGLKTLNFERADWPKEKLLDYFKN-DTIAVLGYGPQGHGQGLNLRDNGLNVIVGVRKDGRSWKKAVAEGWVPGKNLFTIEEAADKGNIVFNLLSDAAQRDLWPTIKPFITPGKTLYFSHGFAITYKHQTHVEAPKGVDVVLCAPKGSGTTLRTLFLEGKGLNSSIAVFQDASGHAHERVVALGVAIGSGYLYETTFAKEVYSDLFGERGVLMGAINGLFRAQYDVLRAQGHSPSEAFNETVEEATQSLFPLIGANGMDWMYANCSVTAQRGALDWLPVFQDLYKSVKDGTESQRALDKNSYRESLEKELKELEIWRAGETVRNLRPE Conco1 -------------------------------------------MKDHGLDVIVGVRK-GRSWDQAVEEGWVPGKSLFEISEATEKGNVIFNLLSDAAQSHLWPTMAPHVTKGKTLVFSHGFSVIYKEDTKVIPPADVDVILIAPKGSGYTVRDLFLNGKGINSSIAIYNNASGKAEERTLALGVAVGSGYIYETTFEKEVYSDLTGERGCLMGGIYGLFKAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGKNGMDWMYANCSTTAQRGALDWKPIVEQIYSEVKNGNETRRSLTKNSYREKLEVELKEIELWRAGKTVRSLRPE Conpu1 RGVKTLNFERADWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGMNVIVGVRKGGESWSQAIEDGWVPGETLFPIEEAINRGTIIMNLLSDAAQSSTWPTIEPLITKGKTLYFSHGFSVVYKEDTKVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSVAVFQDVTGKAKEKAVALGVAVGSGYMYDTTFEKEVYSDLYGERGVLMGAIQGLFCAQYKVLRANGHSPSEAFNETVEEATQSLYPLIGQKGMDYMYNACSTTARRGALDWLPVFEALYKSVRDGTETRKSLEYNGYREDLAKELKEIEIWRAGKVVRSLRPD Copci RGVKTLDFERSDWPLPKLQEYFKN-DTLAMIGYGSQGHGQSLNARDNGLNVIVGVREGGESWKQAIGDGWVPGETLFPIEEAINRGTIIMNLLSDAAQSQTWPELAPLITKGKTLYFSHGFSVVYKEDTKVVPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGKAKEKAIALGVAVGSGYMYETTFEKEVYSDLYGERGVLMGAIQGLFLAQYQVLRKNGHTPSEAFNETVEEATQSLYPLIGQKGMDYMYNACSTTARRGALDWLPIFEQLYESVRNGTETRKSLEFNGYREDLAKELAVIEIWRAGKVVRSLRPD Croqu1 RGIRTLDFERSDWPVSKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIIGVREGGKSWKMALEDGWVPGKTLFPIKEALEKGTIIMNLLSDAAQSQTWPEIKPYLTKGKTLYFSHGFSVVYKDDTGVVPPKDIDVILCAPKGSGVTVRTLFKEGRGINGSIAVWQDVTGQAKEKAVALGVAVGTGYLYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRANGHSPSEAFNETVEEATQSLFPLIGARGMDYMYAACSTTARRGALDWRPVFEELYRSVKNGDETRRSLEFNGYNEDLAKELAEIEMWKAGHTVRQLRPD CryneH991 RGIKTLDFERADWPLDKLQDYFKN-DTLAMIGYGSQGHGQSLNARDNGLKVIVGVRKGGESWKQAQEDGWVPGETLFDIPEAINKGTIIMNLLSDAAQSQTWNEIAPLITKGKTLYFAHGFSVVYKEDTHVVPPKDVDVILVAPKGSGRTVRTLFLEGRGINSSIAVYQDVTGHAKEKAVALGIAVGSGYLYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYEVLRKNGHSPSEAFNETVEEATQSLFPLIGKYGMDYMYNACSTTARRGALDWLPVFEALYNSVRDGSETRRSLEFNSYREDLQKELDEIEIWRAGKTVRGLRPD Crypa2 RGVKTIDFEREDWPKEKLLDYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIIGVRKEGKSWKDAVQDGWVPGKNLFEVDEAISKGTIIMNLLSDAAQSETWPHIKPQITKGKTLYFSHGFSPVFKDRTHVEVPKDVDVILVAPKGSGRTVRSLFREGRGINSSVAVYQDVTGKAEEKAIAMGVAVGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGSHGMDWMYEACSTTARRGAIDWKPVFNSLYDSVKNGEETQRSLDYNGYREKFEAEMEEIEIWRAGKAVRSLRPE Debha1 RGVKTINFERADWPREKLLEYFKN-DTLALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGENLFDVNEAIGKGTYIMNLLSDAAQSETWESIKPQLTEGKTLYFSHGFSPVFKELTHVEPPTNIDVILAAPKGSGRTVRTLFKEGRGINSSYAVWNDVTGKAEEKAIALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHTPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFNDLYESVKNGTETQRSLDFNSYRARLEEELETIEIWRVGKEVRKLRPE Dekbr2 RGLKNINFERADWPREKLLDYFKN-DTLCVCGYGSQGYGQGLNLRDNGLKTIIGVRKNGSSWKAAIEDGWVPGENLFPIEEAIKKGTIIMNLLSDAAQSETWSSIKPLLTKGKTLYFSHGFSPVFNKLTHVEPPKDIDTIMVAPKGSGRSVRSLFKEGKGVNSSYAVWNDATGKAEEKTIALAMAIGSGYVYETTFQREVYSDLYGERGCLMGGIHGMFLAQYEVLRENGHTPSEAFNETVEESTQSLYPMVGKHGMDYMYDACSTTARRGALDWKPVFRKLYANIKSGAETKRSLEFNSYREALEKELDTVEIWKVGTEVRKLRPE Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 RGVKTLSFERSDWPLPKLQEYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWKQAIEDGWVPGETLFPIEEAINRGTIIMNLLSDAAQSQTWPKLAPLITKGKTLYFSHGFSVVYKDLTHVVPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVFQDVTGKALEKATAIGVAIGSGYMYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRANGHSPSEAFNETVEEATQSLFPLIGEKGMDYMYNACSTTARRGALDWTPVFEKLYQSVKNGTETKNALEFNGYREDLAKELKDIEIWVAGKTVRSLRPD Fusgr1 RGVKTMDFERADWPQEKLLEYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWKDAEQDGWVAGKNLFDVDEAIGRGTIVMNLLSDAAQSETWPAIKPQLVKGKTLYFSHGFSPVFKDLTKVEVPTDIDVILCAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAEEKAIALGVAIGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYEACSTTARRGAIDWKPVFNSLYDAVKDGSETKRSLEYNSYREKYEAEMKEIEIWRAGKAVRSLRPE Galma1 RGIKTLDFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWRQAMEDGWVPGETLFPIEEAINKGTIIMNLLSDAAQSQTWPTIAPLITKGKTLYFSHGFSVVFKDDTHVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAIWQDVTGKAKEKAIALGVGVGSGYLYETTFEKEVYSDLYGERGVLMGAIQGLFLAQYQVLRKNGHTPSEAFNETVEEATQSLYPLIGQKGMDYMFNACSTTARRGALDWVPIFEDLYESVKNGTETRKSLEFNGYREDLNRELEVIEIWRAGKTVRSLRPD Ganpr1 RGVKTLDFERADFPKAKLHQIFKD-DTFAVMGYGTQGRAQALNLRDNGLKVILGLRE-GPSFELAKEDGFVPGENLFSIPEAAQKASVIMYLLSDAGQKTGWDTIKPFVTTGKTLYFSHGFSIVFSDQTGVVPPPDVDVILAAPKGSGTSVRRLFLEGKGINGSIAVWQDHSGKAHERACAMGVAIGCGYLYETTFQKEVLSDLTGERGILMGAIQGLFRAQYDVLRSKGHSPSEAFNETVEEATQSLYPLIAENGMDWMYANCSTTAQRGALDWLPVFQKLYHSVETGEETRRSLESNSYKQQLEEELRQIEMWRAGQTVRSLRPE Gloin1 RTMKTLDFERSDWPKEKFQEFFKN-DTIAVIGYGPQGSGQSLNARDNGLNIIIGLRE----------------------------GTIIFNLLSDAAQKELWPKFVPHLTKGKTLYFSHGFSIVFKDETHVIPPKDIDVIMVAPKGSGRTVRSLFLDKRGINSSIAIFQDVSGKAKDTAVALGVAIGSGYLYETTFEREVFSDLFGERGVLMGAIQGLFLAQYEVLRSRGHTPSEAFNETVEEATQSLYPLIGANGMDWMYAACSTTAQRGALDWKPVFERLYEAVANGSETRRVLEKNSYREELEKELEEIEIWKTGKTVRNLRPE Hisca1 RGVKTIDFERADWPREKLLEYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKDGASWKEAVADGWVPGKNLFDVSDAIKRGTIVMNLLSDAAQSETWPTLKPLITKGKTLYFSHGFSPVFKDLTKVDVPKDVDVILVAPKGSGRTVRSLFREGRGINSSIAVFQDVTGKAEEKAIALGVAVGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYAACSTTARRGAIDWKPVFNELYDSVKDGRETKRSLEYNSYREKYEKEMQEIEIWRAGKAVRSLRPE Klula1 RGIKQINFERADWPTEKLLQYFKD-DTLALIGYGSQGYGQGLNLRDNGLNVIVGVRKNGASWKAAIEDGWVPGENLFDVNEAVQKGTIVMNLLSDAAQSETWSSLKPLLTKGKTLYFSHGFSPVFKDLTHVEPPTDIDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAVGSGYVYQTTFEKEVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFQDLYESTKNGSETKRSLEFNSYREKLEAELQIIEIWKVGKEVRKLRPE Lacbi2 RGVKTLDFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWRQALEDGWVPGETLFPIEEAINKGTIIMNLLSDAAQSQTWPQLAPLITKGKTLYFSHGFSVVYKDDTHVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGKAKEKAIALGVGIGSGYMYETTFEKEVYSDLYGERGVLMGGIQGLFLAQYQVLRKNGHSPSEAFNETVEEATQSLYPLIGQKGMDYMYNACSTTARRGALDWVPVFEALYESVRNGTETRKSLEFNGYREDLAKELAVIEIWRAGKTVRSLRPD Lenti61 RGMKTLDFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRENGESWKQAIEDGWVPGETLFPIEEAINRGTIIMNLLSDAAQSQTWPKIAPLITKGKTLYFSHGFSVVYKDDTHVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGHAKEKAVALGVAIGSGYMYETTFEKEVYSDLYGERGVLMGAIQGLFLAQYKVLRKNGHTPSEAFNETVEEATQSLYPLIGQYGMDYMYNACSTTARRGALDWLPVFERLYQSVRDGSETRRSLEFNGYREDLAKELKEIEIWRAGKVVRSLRPD Malgl1 RGMKTLDFEREDWPLEKLHDYFKN-DTFALLGYGSQGHGQGLNLRDNGLNVIVGVRKDGESWRQAMEDGWVPGKNLFTIEEAATKGTILMNLLSDAAQTSTWPELQKYVTKGKTLYFSHGFSIVYKDQTSVVPPSDVDVILCAPKGSGRTVRTLFKEGRGINSSVAVFQDVTGQALEKAVAIGIAVGSGYIYETTFEKEVFSDLYGERGCLMGGIQGMFKAQYDVLRAHGHSPSEAFNETCEEALESLYPLVAQNGMDYMYKACSTTARRGALDWKPVFERLYESVKNGSETRRALEFGSYREDYDKETDAIEMWRVGHVVRALRPN Mellp23 RGIRTLDFERADWPASKLQEYFKD-DTLAMIGYGSQGHGQGLNARDNGLNVIVGVREGGKSWKMAMEDGWVPGKTLFPIKEALQKGTIIMNLLSDAAQSQTWDEIKPYLTKGKTLYFSHGFSVVYKDDTGVVPPKDIDVILCAPKGSGVTVRTLFKEGRGINGSIAVFQDVTGKAKEKAIALGVGVGTGYLYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRENGHSPSEAFNETVEEATQSLFPLIGAHGMDYMYAACSTTARRGALDWKPVFEELYRSVRNGDETRRSLDFNGYNEDLAKELAEIEIWRAGHTVRKLRPD Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 RGVKTMDFERSDYPPAKLQETFKD-DTLTVLGYGPMGRGQALNLRDNKLNVIIGSRK-GASWDKAVSEGWVPGKNLFEINEACERGTVIMNLLSDAAQSKLWNEIKPYLTKGKTLYFSHGFSVIFSEDTGVVPPKDIDVILVAPKGSGTTVRNLFLEGRGINGSVAVYQDVSGKAKDRAVALGVGVGTGYLYETTFKNEVYSDLYGERGVLMGAIQGLFRAQYEVLRAKGHSPSEAFNETVEEATQSLYPLIGANGMDWMYANCSTTAQRGALDWKPIFENLYESVANGSETRRSLTKNSYRAELEVELAEIEMWRVGKTVRKLRPE Mucci2 RGMKTLDFERSDVPKEKLLETFKD-DTIAVLGYGPQGRGQALNLRDNGVNVIIGQRE-GKTYQQAIEEGWVPGKNLFPVLDAVEKGTVVMNLLSDAFQKEIWPQMKPLLTPGKTLYFSHGFSIVYKDQTNIEAPEGVDVILVAPKGSGFTVRRLFQEGRGINSSFAVYKDASGHAKERTIALGIGIGSGYMYETTFEKEVYSDLFGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGERGMDWMYSNCSTTAMRGALDWKPVFEDLYRSVKDGSETARSLDRNSYREKLEEELREIEIWRTGKTVRQLRPE Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RGVKTMDFERADWPAEKLLDYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWEDAIQDGWVPGKNLFDVDEAISRGTIVMNLLSDAAQSETWPHIKPQITKGKTLYFSHGFSPVFKDLTKVEVPTDVDVILVAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAKEKAVALGVAVGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGAHGMDWMFDACSTTARRGAIDWKPVFNNLYDSVKNGDETKRSLEYNSYRERYEAELDEIEIWRAGKAVRSLRPE Orpsp11 -MVKVINFERSDFPQEKLNEIFKD-DTFAVIGYGTQGRNQSRNLRDKGFKVVVGLRK-GPSWDLAKEDGWVEGETLFEITEACQKGTIIMYLLSDAGQKAAWSTIKELVH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RGIKTIDFERADWPREKLQEYFKN-DTLALIGYGSQGHGQGLNLRDQGLNVIVGVRKDGASWKEAIQDGWVPGKNLFDVTTAIEKGTVIMNLLSDAAQSETWPTIKPLLTKGKTLYFSHGFSPVFKDLTKVDVPKDIDVILVAPKGSGRTVRTLFREGRGINSSIAVFQDVTGQAKERAIAMGVAVGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGGNGMDWMYAACSTTARRGAIDWKPVFNDLYDSVHNGTETKRSLDYNSYREKYEKEMQEIEIWRAGKAVRSLRPE Phybl2 RGFKTLNFERSDVPKEKLLDTFKN-DTIAVLGYGPQGRGQALNLRDNGVNVIIGQRE-GKTYDQAIEEGWVPGKNLFPVLDAVEKGTVVMNLLSDAFQKEFWPKMLPLLTPGKTLYFSHGFSVVYKDQTEIVPPKDIDVILVAPKGSGFTVRRLFQEGRGINSSFAVHQDASGHAKERTIALGIGIGSGYMYETTFEKEVYSDLFGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGERGMDWMYSNCSTTAQRGALDWKPVFEQLYESVKNGSETARSLDRNSYREKLEEELKEIEIWVTGKTVRQLRPE Picst3 RGIKTINFERADWPREKLLEYFKN-DTLALIGYGSQGYGQGLNLRDNGLNVIIGVRKNGASWKAAIEDGWVPGENLFDVNEAISKGTYIMNLLSDAAQSETWASIKPQLTEGKTLYFSHGFSPVFKELTHVEPPTNIDVILAAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAEEKAIALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHTPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFNDLYESVKNGSETQRSLDFNSYREKLEEELQVIEIWRVGKEVRKLRPE Plicr1 RGIKTLDFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWRQAQEDGWVPGETLFPIEEAIDRGTIIMNLLSDAAQSQTWPTIAPLITKGKTLYFSHGFSVVYKEDTKVIPPTDVDVILVAPKGSGRTVRTLFKEGRGINSSVAVFQDVTGKAQEKAIALGVGIGSGYMYETTFEKEVYSDLYGERGVLMGAIQGLFLAQYKVLRANGHTPSEAFNETVEEATQSLYPLIGAKGMDYMYNACSTTARRGALDWTPVFEALYKSVKDGTETRKSLEWNGYREDLAKELAEIEIWRAGKVVRSLRPD Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RGVKTLDFERADWPASKLQEYFKN-DTLAIIGYGSQGHGQGLNARDNGLNVIIGVREGGASWKAAEADGWVPGKTLLPINQALEKGTIIMNLLSDAAQSQTWDSIKPYLTKGKTLYFSHGFSVVYKNDTGVVPPKDIDVILCAPKGSGRTVRTLFQEGRGINGSVAVWQDVTGKAKEKAVALGVGVGTGYLYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRENGHSPSEAFNETVEEATQSLFPLIGAHGMDYMYAACSTTARRGALDWKPIFEALYKSVKNGDETRRSLEFNGYSEDLAKELAEIEIWRAGKTVRGLRPD Punst1 RGVKTLNFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRPEGESWKQAIEDGWVPGETLFSIEDAINRGTIIMNLLSDAAQSQTWPTVAPLITKGKTLYFSHGFSVVYKEDTKVVPPADVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGKAKEKAVALAVGIGSGYMYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRKNGHSPSEAFNETVEEATQSLFPLIGAKGMDYMYNACSTTARRGALDWTPVFEKLYESVRNGTETRKSLEFNGYREDLARELKEIEIWRAGKVVRSLRPD Rhior3 RGLKTLDFERSDVPKEKLLETFKD-DTIAVLGYGPQGRGQALNLRDNGVNVIIGQRE-GKTYQQAIDEGWVPGKNLFPVLDAVDKGTVVMNLLSDAYQKEIWPQMKPLITPGKTLYFSHGFSIVYKDQT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 RGVKTLDFERADWPLPKLQEYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVREGGESWKQAQEDGWVPGKNLFPIDEAIKKGSIIMNLLSDAAQSQTWKDIKPLITEGKTLYFSHGFSLVYSKDTGVEAPSNVDVILCAPKGSGRTVRTLFKEGRGINASIAVWQDVTGKAMEKARALAVAVGTGYAYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRENGHSPSEAFNETVEEATQSLFPLIGQYGMDYMYNACSTTARRGALDWKPVFEKLYKSVRDGT------------------------------------- Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 RGLKQINFERADWPREKLLDYFKN-DTFALIGYGSQGYGQGLNLRDNGLNVIIGVRKDGASWKAAIEDGWVPGKNLFTVEDAIKRGSYVMNLLSDAAQSETWPAIKPLLTKGKTLYFSHGFSPVFKDLTHVEPPKDLDVILVAPKGSGRTVRSLFKEGRGINSSYAVWNDVTGKAHEKAQALAVAIGSGYVYQTTFEREVNSDLYGERGCLMGGIHGMFLAQYDVLRENGHSPSEAFNETVEEATQSLYPLIGKYGMDYMYDACSTTARRGALDWKPVFQDLYESTKNGTETKRSLEFNSYREKLEKELDTIEIWKVGKEVRKLRPE Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 RGVKTLDFERADWPLPKLQEYFKN-DTLALIGYGSQGHGQGLNARDNGLNVIVGVRKDGESWKQAQEDGWVPGETLFPIEEAIGRGTIIMNLLSDAAQSQTWPTIAPLITKGKTLYFSHGFSVVFKDDTHVVPPPDVDVILVAPKGSGRTVRTLFKEGRGINSSVAVFQDVTGKAKEKALALGVAIGSGYMYDTTFEKEVYSDLYGERGVLMGAIQGLFRAQYEVLRKNGHTPSEAFNETVEEATQSLYPLIGAKGMDYMYNACSTTARRGALDWLPIFEKLYQSVRDGTETRKSLEYNSYRQDLARELEEIEIWRAGRTVRSLRPD Schpo1 RGMRVMDFERSDWPREKLVDYFKN-DTLAIIGYGSQGHGQGLNARDQGLNVIVGVRKDGASWKQAIEDGWVPGKTLFPVEEAIKKGSIIMNLLSDAAQTETWPKIAPLITKGKTLYFSHGFSVIFKDQTKIHPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSFAVYQDVTGKAQEKAIGLAVAVGSGFIYQTTFKKEVISDLVGERGCLMGGINGLFLAQYQVLRERGHSPAEAFNETVEEATQSLYPLIGKYGLDYMFAACSTTARRGAIDWKKVLNELYDNVENGNEAKRSLEYNSYRELYDKELEEIEIWKAGEVVRSLRPE Sorma RGVKTMDFERADWPAEKLLDYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIIGVRKNGKSWQDAVQDGWVPGKNLFDVDEAISRGTIIMNLLSDAAQSETWPHIKPQITKGKTLYFSHGFSPVFKDLTKVEVPTDVDVILVAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAKEKAVALGVAVGSGYLYETTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGAHGMDWMFDACSTTARRGAIDWKPVFNNLYDSVKDGSETKRSLEYNSYREKYEAELEEIEIWRAGKAVRSLRPE Sphar EVFNVMDVGRDLFP--KLTESFGGVKKIGVIGWGSQGPAQAQNLRDSDITVTVGLREGSSSMKLAEEVGFKENGTLGEMYDVIRESDLVCLLISDAAVAHEYPKVFENLKKGATLGLSHGFLLGHLKNTGDSFPKDTNVIMVAPKGVGASVRRLYEQGKGINASFAVEQDADGKATDIALAWSVALGSPFTFYTTMDSEFKSDIFGERCILLGGVHGMMMAQIDTLLDRGHCYSEVANESVIEAVDSLNPFMHARGVAYMVDSCSVTARLGSRKWLPV-----------------LDENK-----EKLFDDFRIHAVMKTCGEMRPS Spipu1 RGVKTLDFERSDFPKEKLHKIFAN-DTFAVLGYGTQGYAQSLNLRDNGLKVIVGVRKGGHSWEAAKKDGWVEGKTLFSIEEAADKGTILMYLLSDAGQKEGWPTIKPYVTKGKTLYFSHGFSVVFPEQTGVVPPKDVDVILAAPKGSGATVRSLFLEGRGINSSVAIHQDVSGQARERAFAMGVAIGSGYLYETTFKKEVYSDLTGERGILMGAIQGAFAAQYDVLRAKGHSPSEAFNETVEEATQSLYPLIAKNGMDWMYANCSTTARRGALDWKPVFEALYESVENGSETKRSLEENSYRERLEAELREIEMWRAGRTVRSLRPE Sporo1 RGVKTLDFERADWPLPKLQEYFKN-DTLALIGYGSQGHGQGLNARDNGINVIVGVREGGESWKQAQEDGWVPGKTLFPIEEAINKGTIIMNLLSDAAQSQTWKDIKPLITEGKTLYFSHGFSLVYAKDTGVEAPKNVDVILCAPKGSGRTVRTLFKEGRGINASIAVWQDVTGKAMEKARALAVAVGTGYAYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYKVLRENGHSPSEAFNETVEEATQSLFPLIGQYGMDYMYNACSTTARRGALDWKPVFEALYKAVRDGTETRRSLEFNGYREKFAIETKEIEIWRAGKTVRSLRPD Stehi1 RGIKTLDFERSDWPLAKLQDYFKN-DTLALIGYGSQGHGQGLNARDNGINVIVGVREGGESWKQAQEDGWVPGETLFSIEEAINRGSIIMNLLSDAAQSQTWPKLAPLITKGKTLYFSHGFSVVYKEDTKVIPPTDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVWQDVTGKAKEKATAIGVAIGSGYMYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYQVLRENGHSPSEAFNETVEEATQSLFPLIGQYGMDYMYNACSTTARRGALDWLPVFRALYQSVRDGTETRKSLDFNGYREDLAKELKEIEIWRAGKTVRSLRPD Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 RGVKTLDFERADWPLDKLQEYFKN-DTLAMIGYGSQGHGQSLNARDNGLKVIVGVRKGGESWKQAQEDGWVPGETLFDIPEAINKGTIIMNLLSDAAQSQTWPEIAPLITKGKTLYFSHGFSVVYKDDTHVIPPKDVDVILVAPKGSGRTVRTLFLEGRGINSSIAVYQDVTGKAKEKAIAIGIGIGSGYLYETTFQKEVFSDLYGERGVLMGGIQGMFLAQYEVLRKNGHSPSEAFNETVEEATQSLFPLIGKYGMDYMYNACSTTARRGALDWLPVFEALYKSVRDGTETRRSLDFNSYRQDLQKELDEIEIWRAGKTVRGLRPD Trire2 RGLKTVDFERADWPQEKLLEYFKN-DTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGKSWNDAIQDGWVPGKNLFEVDDAISRGTIVMNLLSDAAQSETWPSIKPQLTEGKTLYFSHGFSPVFKDLTKVDVPKNIDVILCAPKGSGRTVRSLFREGRGINSSFAVYQDVTGKAEEKAVALGVAIGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMFEACSTTARRGAIDWKPVFNSLYDSVKDGSETKRSLEYNSYRQKYEAELEEIEIWRAGKAVRSLRPE Umbra1 RGYKTLDFERADVPREKLLETFKD-DTIAVLGYGPQGRGQALNLRDNGVNVIIGQRE-GKTYQQAIEEGWVPGKNLFPILEATEKATVVMNLLSDAFQKAIWPDMLPLLTPGKTLYFSHGFSVVYKDQTGIIPPKDVDVVLVAPKGSGFTVRRLFQEGRGINSSFAVFQDVSGKAKERTIALGVGIGSGYMYETTFYKEVHSDLVGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGEKGLAYMFANCSTTAQRGALDWKPVFEDLYESTKNGSETARSLDRNSYREKLEAELAEIEMWRAGVTVRSLRPE Ustma22 RGLKTIEFEREDWPLEKLQDYFKN-ETFAILGYGSQGHGQGLNLRDNGLNVIVGVRKDGASWKEAIEDGWQPGKNLFSIEEAAEKATIAMLLLSDAACAQVYASVKDKMPNTHTLYFSHGFQITYQKETGFEAPKDKDIILCAPKGSGRTVRSLFLESRGINGSIAVFQDVSGKALEKVSAMGVAVGCGYLYETTFEREVYSDLYGERACLMGGIQGLFKAQYDVLRANGHSPSEAFNETCEEALQSLYPLVGANGMDYMYKACSTTARRGALDWKPVLEKLYESVRNGSETRRALEFGNYREDFDKETDAIEMWKVGHKVRALRPE Walse1 RGIKDIVFERSDYQGSKLQEILGN-ETLAMIGYGSQGHGQALNARDQGIKVIVGVRKDGQSWKEAIEDGFVPGESLFPIEEAIDRGTIIMNLLSDAAQSQTWKDIAPLIKPGKTLYFSHGFSVVYKEDTGVIPPKDVDVILVAPKGSGRTVRTLFKEGRGINSSIAVFQDVTGKAFEKAKALGIAVGSGYLYETTFEKEVYSDLYGERGVLMGGIQGMFLAQYEVLRKNGHSPSEAFNETVEEATQSLFPLIGKYGMDYMYNACSTTARRGALDWKPVFEALYESVRDGTETRRSLEFNGYREDLQKELEIIEVWRAGKEVRKLRPD Zygro1 RGLKQINFERADWPREKLLDYFKN-DTFALIGYGSQGYGQGLNLRDNGLNVIVGVRKNGSSWKAAIEDGWVPGENLFDVTEAVQKGNIVMNLLSDAAQSETWPTIKPLLTEGKTLYFSHGFSPVFYDLTRVEPPTNIDTILVAPKGSGRTVRSLFKEGRGINSSYAVWKDVTGKADEKALAMSVAIGSGYVYQTTFEKEVNSDLYGERGCLMGGIHGMFLAQYEVLRENGHSPSEAFNETVEEATQSLYPLIGSLGMDYMYDACSTTARRGALDWKPVFQDLYESVKNGSETKRSLEFNSYRAKLESELETIEIWRVGKEVRRLRPE [Cluster2726.fasta_al_trimmed; alignment length = 171] Allma1 FLVEATGIATQARRGYLMTHAEREACALLLGIRRME----------------------------------AHTVQELERENRALLYASKLDEIKAEQSLLTIAQLQADIAQHLATQQTAIETLFEEAAQQTDQVREGNAQLVQAREAAKGARLWFLMVLVLSFTLLFLDWY Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 FLKEAYRINSSIRHSYLLTDSERDSTALLLRIANLSTVRESILWFLRLERAAERDMVEKRIVREKEKSLSPEQLQLFAEENDLLLYEDALSKVQAEKSLLEISSLQQTLVSHLSTQEEYIEQLVMDASTTTTNIGQGNKELKRATQRR-STAQAVFGTVGLCTWLVVWDLI Aurde31 -MEEASAVLNAIRRPYLLSNDERDQARVVLSVKEMESHNASVTWYLNLTEASAKEMQEERVQMERTRTLTQSQILQFESENASILVQDTLASVQAESSLLDISALQMELVAHLAQQTEITDKLYEDAISTSETVDAGNRQLVEARRRQGDSRLFVLFLLGASFALLFLHYY Batde5 -----------------MTDEKKDVIQAIIKIQALSSMRESVVWILELMSTSNQAMQEYRLTEARSSSFTVGERAALEQDNSTMMLESTLTQVRATQSLNEIAQLQSTLAHHLQAQSETIDSIYDDAEKANQTIAKGNDNLKSAQKYFGGPRWWVLVLLTISGLLLLLDSF Botbo1 FLTEAYSILKGIRRPYLLSNEERDQSRVILTVKELEAHRSNITWYLTMADVSQKEMQEERVQLERTRTLSPSQILQFEEENAAILQEDMLQSVQAEARLLDISALQTQLIAQLAKQTEVVDQLYDEAITSQAEVDKGNVQLKQARERGRESRQWLLFILGATMALLFLHWY Botci1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel FTNISNVALSDHSQDYIMSPMERESVKDKLTNVQLGRVQEGLTVYLKIAMVSLEHLQRLHAELEFSDKFAVEFQQQAELRKKEFV-EDQDDEILLQQHLTEIASLHTVFSEKVLEQDRDVELIHDHALHTTENITDGNEWIRKAITNSGKQRAFLLSIVVLSFALLFIDWY Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow FAASARQIASEHRHDYL---KQCTQAEALVQGSVKQAHRTAVVNLLTL-----AQGKEVMRRVKR---LSPEELMELEQDNERVFLHVLSDQTRAETRMVEIAQLQAQFASHVMEQAALADSIHDLAVHTTANVAQGNEQLTSASKHLGSFRLWILFLLLCSFCLLFLDWY Catan2 VVVQADTIMAHIRRAYLLGAAERDQVAMVLGIKQLSTHYSSMVWVLNMFRVTNRRLHERRVALDTSATAPAQMIQEFEAENKELLFESKLDEVKAETSLLTIAQLQTELAQHMAVQQSQIESLVDDAVVHVANVRAGNVELTKAREYGKTARFWFLIMLVVSATLLFLDWY Cioin FEIKSRGIVTDNRHGYLMTNQEKDKGEKFMQLEQLKFHQKLVVEIVELKLVFQNEQKSVRVIVERNTVLVPDDDETFAQENAQLLMNSLSDEVRIGGKVVEIAKLHEMFSEQVFQQEADIELVSEKIVESSENVKDGNEELREAIKNNAGFRVWVLFLVMCSFSLLFLEWY CocheC53 FVKEAYRIRTSIRQSYLLSDAQRNEAKQSIRIKTLGAHRESIIWSLQLEECGQSNMMEIRLEVEKSKSLDPEQLQLFAQENQDMLYEDQLDKIRTEKSLTEISELQSTLASNLSMQAAHIDQLVEDSLNTQENVGSGNKELKRATERG-STAQKVFATSVFCATLVLWDLF Coere1 FLNEAYIIAKDIRPAYLLSDPERDEIKAAVRIHSLSALQSSVVWWLNLRSTNQAEMQEQYLKLERQRNLSEQQLQQLRSENETMVFESALDRIRTQRSVVEISALQSQLATELNSQMQQTERLYNEAVGAVDAVDKGNEYLISARKHQSSTRKWVLIFIMLSLVLLFLDWF Conco1 FLIEAYRIAEVARRGYLMSDEDRDETKIIIQIQKLETHHSAITWLLNLVDVSQKRLQEQRLELDRQEILEPEQQQMLELENKELVFESSMNQIKIERSLVDISQMQSTLSTHLAIQSKETEKLYSDAVNSTDSMSAANQYLRE---------------------------- Conpu1 YLVEAYAVLKRIRKPYLLSNEEREQARAVLSIKEMEAHHSSITWYLSLTEAAQKDMQEERIQLERSRTLSQSQILEFETENANILVQDTLESVQAEARLMDISNLQMELVTHLTRQSELTDQLYEDAMATTSTVEKGNVQLREARRRAKDSRLYILFLIGASLSLLFLHYY Copci YIHEAYTILSSIRRAYLLSNEERDQARTILQVKEMEAHRSSITWYLGLTEASQKEMQEERVQLERTKTLTSSQILQFEAENAAILVQDTLESVQAESRLMDISALQMELVTHLTRQTELTDQLYEDAIATTSTVEKSKAELKKAQERGKDSRLYLLFLLGASFSLLFLHYY Croqu1 WTKEAQVLSNTIKRPYLFSEKEKDEVGVGLKVRALESHRASILWFLNLTELSKKNQQELRAQIQQLSKLSASQLQQFDSESSALLTENTLASIKTESSLLEISNLQSELVFHLTQQTELIDTLWDDAVVSTGKVEQGNLQLLTAKENNRESRIWLLFLLGASFALLFVDYI CryneH991 FLKEAYRIHTSVRKAYLLTDKERDEARMILRVGILEAHHASILWTLNLARLTGSDLQNERIREERSKT-----IRAFESENNALLMSSTLSSVLAEASLLEISQLQSELVRHLAQQTEVVEQLYEDAVGSVAEVKRANEQLTKARERGKDGRLFLLFILGASFSLLFLDWY Crypa2 FLKTASSINRSIRQAYLLTDADRNIAKDMLRINVLTEHRGGVIVYLQLQAAAARTMMETRLEMEKNRTLTDEQKQMFERDNQDMVYNSATEKVRVERSLVEIAELQQMLVENLTVQSAHIDQLVADSERTEENVGGGNKHLQKATQRKFSQARMTFAASALCTFLIVWDLI Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi IIKASISIYNEHKEAYVMTDEEREESTNQIEIKSIEVLYSNIVDQLKLNNVSNKKLRSFRLKLKESEKFDEEEMQIYEQQNSELKLETLADQIEINRQVEELSQLFDEITPHILQHKEVITNIHTTTIEATNYVTRGNNQIYEATKKSFDFRVMVLFLIISSLSLLVLNWY Dmel FAKQAKEVCNENRTAYMMTDAQRDLSEKFVTLAKMRQHIDAVLDLLVLHSVEQLDQKKYRVAADKKKILSAEDVQLFEAENVHIYLQGVSEEVEIEKNVVDIAQLQDIFTEKVAMQQHNIDRIVSAVVGTTENVKDANEQIRQATQRNAGLRVWSLFLLVMSFSLLFLDWY Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba FHTATEKIASEARGPLPLQEERAGSVRQRLGVNQLQAHLLGVLSCLMLDRTETSRAIQARAQLKDFDSRRNEELASALLQSDSLFMVGIQPDIHLQTLIQHISSQESIIANHVKEQAAQIERLYSEAIETTELIRSGNRHMKSAIKHTSSSRKMWLIMVGLTLTLLFLDWL Fomme1 YMREAYNILNSIRRAYLLTNEERDQARIILSVKQLEAHNSSVTYYLNLAQAGQKEMQEERIQMERTRTLSASQIQQFESENANILVQDTLASVQAEQRLMDISALQTELVTHLTKQSEITDQLYEDAISTTAAMEKGNEQLTEAKRRAKDSRLYILFLVGTSLALLFLHNY Fusgr1 FLKEAYRINSDVRQAYLLSDRDREEAKQMIRIRALDIHRDGILWFLRLESCCRQDMMEARLEMEKSRSLTEEQIQMFEEGNQDMMFESSLDKVRAEKSLLEISELQSLLVNNLATQSAHIEQLVSDSFSTTENVGGGNKELKKATQRA-SPAKYTFAAGGLCAFLVVWDLI Galma1 YVAEAYNILNSVRTAYLLSNEERDQARVILTVKEMEAHHSSITWYLSLTEASQKEMQEERVQLERTRTLSASQILQFEAENANILVQDTLESVQAESRLMDISALQMELVTHLTRQTEITDQLFEDALATTSTVEKGNEQLKEAKRRAKDGRLFILFLIGASLSLLFLHYY Ganpr1 FTKEAYRIAQSIRGPYIVSARQRDEIAAFFRVRSLSDHRTSMIWYLELMQATQREMQEERDSLSASPSLTSAELQQLADENAVLLLEGRTEEVVIAQNVHEIAQMQAELGRLLVGQDDTVTQIHLDTGATVDALTRANEYLRNASMTGSDMRMMVIFFLVMAFTVVFLDWY Gloin1 FLKEAYRIAFSIRKAYLLTDKERDEAKIVIQIKKLEAIRSSITWYLNLTEISKKDQQETRIEIEKRESLTAEQKMMLEMENETMMLATALEQVNAEKALLEISNLQTVLSNHLAVQTQQTDKLYAEAIATTDRVQEGNLMLHQARQRASDTRKWILFLIIASFILLFLDWY Hisca1 FLKEAYRINSSIRQSYLLTDTDRDTTALVLRIANLATIRENVLWWLRLEGVAERGMVEKRIIKEKEKSLSPEQLQLFAQENDGLLYEDTLGKVKAEKSLLEISSLQQTLVMHLSTQEDFINQLVSDAANTETNVGQANKDLKRATERL-STAQAVFGTVGLCTWLIIWDAI Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 YVTEAYTILNNVRSPYLLTNEEREQARVILTIKEMEAHHAGMTWYLTLTEASQKEMQEERVQLERTRTLSASQILQFEAENANILVQDTLESVQAESRLMDISALQMELVSHLTRQTELTDQLYEDAIATTSTVEKGNVQLKEAKRRAKDGRLFILFLIGASLSLLFLHYY Lenti61 YVKEAYNVLNSVRKAYLLTNEERDQARVILSVAQLEAHHASITWYLSLTETSQRDMQEERVQLERTRTLSASQIQQFEEENANILVQDTLASVQAEARLMEISALQMELVTHLTKQTEQTEQLYEDAIATAATVEKGNEQLKEARRRARDGRKWILFLIGASLSLLFLHYY Malgl1 -QREASNLLGSIQASLQQKRVDMQ-------YEKLS--QQG------------------------VDVLSTEQRQVFEEEASALVLQADLAAVQAEQQLQDISSLQTKIVQHLEEQNEHVDTLLSDAGTHGEQVTRGNQQLRRAKERNRQANRLLSFFVLSGLLLLLMHCA Mellp23 WSKEAKVVNHTIKRAYLFSEQEKDEVGVGLKVRALELHRASILWYLNLTKLSQKDQQETRAKRQKLSNLTSTQLHQFDSESSALLTETTLTSIKTESSLLEISNLQSELVLHLTHQTELIDTLWDDSLVSTGKVSEGNLQLLKAKENNRESRIWLLFLLGASFALLFVDYI Mnele FTKNATSVLKETKDKYILSDQQRLDANMFMVISSLSAHQEGVIFVLTLKLTCDSRTKAIHVTLEQHRLLSPEEVQMMELENENMYLTALSSEVQIEGTVMEISRLQEIFTEKVLTQSEQIFELHRTAVETTGNLPPGTMQLTDKQHRTQQPSNNLHDIRLVSDGLSAVNYT Monbr ALFRAL----SLRAALE----ERQDTLTVVSLVQLE-----------VTSLPN----------DWLKKPSPAMSQALAQQVRQFRLHDMAREVDAQDTLYELASMQSRLMGKLQEQDVTIEQIQQDAETTLHNVDRGNEELTEAIRYNRDFRQGVLFFIILSLCLLFFDYL Morel2 WLKEAHQISRATRPAYLLSDKDRDSVKVMMRIEELEQHRQGVTLYLNLASLATKDQYEVRIEMEKRESLTAQERQMLEMENENIVLETELNQVRLETSMIELSTLHSTIQEHLEIQTQQTNRLHEEAQTAINHIDAGNEQLIKAGKRNNSTRKWILFLILASFVLLFLDWY Mucci2 FTKEAYRIYQTIRPAYLLTDRERDEAKLIIRIKELEVHRSSMTWFLNLMQVSQKEQQEIRLEIEKSENLSQEQIQMLEKENSIMLLNNTLNQVKAEKALLEISTLQTQLTNHLAAQTIQTDKLYADAIATTEKVEQGNLQLITARERNKSSRNFMLFLLGASFVLLFLDWY Mydma FNSHAQAVVQTYQTDYLLTDIERDQSQKLMKIESLKLHSTAVVELLQLKDVCRSQLRAYRVAVDRKRMFTKEETQLFEEENERLFMNTMMKEVRIEGKVIEISQLQEIFQEKVLAQSSQIQNIHNSAVATTENVKDGNEQIRDAIKNSATFRVWILFLVMCTFSLLFLDWY Neucr2 FLKEAYRITSNLRQAYLLTDRDREEAKATLRIRALEAHRESVIWYLRLQETARQAMMETRLEMEKNRSLTDEQIQMFEKGNQDMVFESTLDKVRAEQSLLEISELQNMLVSNLTTQSAHIDQLVAESFETTEGVDRGNKELKKSTNRA-SPARYTFAATGLCAFLVLWDLI Orpsp11 FLKDAYKIEKSIRKSYLMTDRQRDDSKQYIKINNLSLHREAIIFSLNLMKVADKNQQEKRLNLQKKESLSQELRMELEEENQEMLLESDINQVRATQSINEISQLQATLSQQLQIQQNIIETLHEDSWKSVDTMKQANQKLLSAQKHFSDRRVWMLFLVMSSLILLFLD-- Pench1 FLKEAYRINSSIRHAYLLTDPERDETALLLRIANLSTVRESVLWFLRLECAVSRRMVEKRIVREKEKSLSPEQLQLFAEENDSMLYEDTLGKVQAEKSLLEISSLQETLVSHLATQEEYISQLVSDVDTTQTNVGQGNRELKRATERR-STAQAVFGTVGLCTWLVVWDLV Phybl2 YTKEAYRINQSIRRAYLLTDRERDEAKLVIRIKDLEIHRSSITWLLNLMEVSNKNQQEIRLEIEKSENISQEQLQMLEKENSVMLLNNTLNQVRAEKALLEISNLQSQLTHHLAVQTLQTERLYGDSIATTERVEQGNLQLIQSRER------------------------ Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 YVAEAYTILNNIRKPYLLTNEERDQARVILSVKEMEAHHASITWYLSLTEASQKEMQEERVQLERSRTLSQSQILQFESENATILVQDTLSSVQAEAHLLDISALQLELVSHLSRQTALTDQLYEDAVATTGTVEKGNAQLREARRRARDGRKWVLFLVGASLSLLFLHYY Polpo ILKASASILEDNREAYIMTDEDRDTSLKQIEIAKLDYMFMSIIDQLRLNQVSTKKQRDFRLTIKENQKLDNDEQLIFEQQNASLILESLSDQILIERQIEELSTLFDEITPHIMAQRETLNTIYTTNVQATNYIHRANQHIQDATKKTFDFRVMVLLLITASFVLLFLNYY Pucgr2 WTKEAQLVANSIRRAYLFSENEKDQVAVGLKVRALEGHRASILWFLNLTDLGKKDQQETRAKMEKVMKLTSAQIQQFEKESTEVLTENTLKSIKTESSLLEISNLQTELVYHLTQQNEMIDQLWDDSIISTGKIKQGNQQLLSASESNKESRMWLLFLLGSSFALLFVDYM Punst1 FIAEAYVVLKSIRKPYLLTAEERDQARVILSVKEMEAHHASVTWYLSLAEASEREMQEERMQLERTKTLSQSQILQFESENAAILVQDTLASVQAESRILEISALQTELLTHLQTQTQITEQLYEDAIAATGQVEKGNVQLREAKRRAKDSRLFVLFLIGASLSLLFLHYY Rhior3 FTKEAYRIYRSIRPVYLLTDNERDEAKLIIKINELEVHRSSMTWLLNLTQVSKKDQQEIRLEIEKSENLSKEQMQILEKENSVMLLNNTLNQIKAEKALLEISTLQTQLTNHLAAQTLQTDRLYADAVATTETVERGNLQLLSAKERNRGSRRFILFLIGASFVLLFLDWY Rhoto1 WTRRAEQVATSIRRAYLLTDRERDEVKVALRVRELESHRSLVTFYLNLASVSQRDQQEARVQLEKTQSLTADQIQQFEAEESALLTQSDLESLKAEFSLLEIASLQSQLAIHLTQQAELTDKLWEEAITVSGEVDRGNKQLKKAKERGRESRMWLLFLFMSSFTLLFLDYY Rozal11 FLKEAYSTIHENRHEYCMSNERTSDSSMFIQIQTMEIHRESVIWYLNLAEAAGRQLQEIRLQMKNKENYDLQETLLLEEENKNIAFNSLIDQLE------------------------------------------------------------IRFAIG----------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ALHSAFVVEEGIATATTSVLPQRQQTAKALQVERVSHQRAALRWRHEYLNLPRRKQARRRAGVDRRHGPE-ACTQALKQEHAQLQCHDMLRDIGMHAQVGEISKLQQRFSQLVDTQQQTITHITEATVSTLGNVSAGNRELKEASRHNRDFRLVIIFFAVLTLALLCLDWL Schco3 YLREACTILDSIRKPYLLTNEERDQARVILSVKEMEAHHAGITWYLNLTEASQKEMQEERVQLERTKTLSSSQIQQFEAENASILVQDTLEAVQAESRLQDISALQMELVTHLTQQTELTDQLYEDAISATETVEKGNVQLREARRRAKDSRIFVLFLLGASFSLLFLHYY Schpo1 FLAEGYRIHEKIRGAYLLDEVQRDEVSSAISIAKLQAHHSSVLWYLQLSDVSSYHLQ----------DFTQQQLQELEQENDVLLFEHTMERLRTGKSLADITRLQSEISAQLSIQSSAAEKLYDDALNVMDSLSGGNQQLIKAKSRSSRTARLLFIFTVMGLLLLSLDRI Sorma FLKEAYRITSNLRQAYLLTDRDREEAKATLRIRALEAHRESVIWYLRLQETARQAMMETRLEMEKNRSLTDEQIQMFEKGNQDMVFESTLDKVRAEQSLLEISELQNMLVSNLTTQSVHIDQLVSESFETTEGVDKGNKELKKSTNRA-SPARYTFAATGLCAFLVIWDLI Sphar -----------------------MAVQRLATIVVLKKHRQLVLLILRLADTMAEVLQSERAVQERARLLTAAEKVVIEAENKTLLMNTLVSAAMAQKRMLEIAKLQQVFTRNVQEQAEDLDLLYDTAVDTTENITAGNELLHKAVNDGFDFRVWVLFLLMCSFSLLFLDWY Spipu1 FLKEAYRLLERARKYYLMTDKQRVETQILVEVAVLSEHRNSVIWLLRLMDVSNKDMQERLMRLSREDTLEPQERQLLESENAALLLESSIDQVRTTQSLNVISSLHSRLSHELQSQSETIGFLYDDAWRSTESVKNANLQLISAQKHFGDARIWVLFLVIASAILWFLDYY Sporo1 WTLQASQVATSIRRPYLLSDKERDEVKVALRVRQLESHRSYITLYLNLQKVSERLQQETRVQLDKTSSLTQEQIQQFEAEESLLVPVSTRRSLVAE--------------------------------------------------------------------------- Stehi1 YMKEAYSIHNNIRKPYLLTNEERDQVRMILAVRAMETHNNNVTLYLTLADVSQKDMQEERVQTERTKTLTPSQIQLFESENAQILAQSQLASIQAESRLLEISALQLQLVEQLGRQTEVAERIWEDAAQTREEVDKGNVQLREARRRMRDGRVGLLFLIGASLSLLFLHYY Tapde11 YLAEASKLYQKTRKAYLLTDTQRDEVKANIRVKELESHRASVTWYLNLLAISQADIKTIRLEEEKRLALSADQLQEFESENGQILFENQVTQIRVQTKLMEIAELSTELQQHLASQTEMTDRLMTEAEQTTADVTTGNQQLTKAKRRNKTMRLYITIFLVLAFTLLFLDYY Thetr MMRKARRARSALREG--TTEAEKDGLETALHLDALAAFHLSVLRALNMLEVDEKALRAARAQLDVATLTSPALAAQLAVENRALAVATMVDQVRAERKMVHIHELHSVMASRLSEQAELIDALLHNASVSVANMETGNTELRKYRESSVSYRIYMLFLIGASFTVLFLHWY Treme1 FLKEAYRIHNSIRKPYLLSDRERDEGRMILRVQLLEAHRASIFWTLDLTRTTSSSLQEERARLEREKTLSPALIQQLENENNTLLMESTLSSVLAEKSLLEISTLQTELVRHLVQQTEITDRLYDEAVGSVGQMGSANEQLKKAKKRGGEARFFLLFLLGASGALLFLHWY Trire2 FLKEAYRINSDVRQAYLLSDREREEAKQMIRIRSLDGYRDGVLWFLRLELCCRQDMMETRLELEKSRSLTDEQVQMFEEGNQSMMYESTLDKVRAEKSLLEISELQTLLVNNLTAQSENIELLVADSASMADNVGGGNKQLKKATQRP-STARYTFAASGLCAFLILWDLI Umbra1 FMKEAYRIEQITRKAYLLTDKERDEAKMIIRVKDLEVHRSGVVWLLNLMEVSQKNQQETRLAVEKSENLSQDQLQMLERENDAMLMENTLNQVRAEKALLEISTLQSQLTSHLAVQTAQTDQLYAEAIATTDRVEQGNQQLVRARERNRGTRKMILFLIGASFVLLFLDWY Ustma22 WLAQAYIIRKSIRRKYLLSDTQRDEVKVVIKIRELEAHRASITQYLSLSRASASDMQEARLQREKTKSLSASQIEMFETESSELILESDLAAIKAESRLYEISELQTQVVQQLEQQGEITDQLLDEAIGVGTEVGRGNEELRKARQRSREADKFLTFLVGSGLALLFLHWM Walse1 INREAKYLLSSIPAQYAQNNASLDVVTSLLALKELDQHQHGKLISLNLIKLSTQSLQKQRQEYEQIDNLSQEQIQMLERENDELVNKRDLIEIEAQHSLLSITSLQSEILTHLTQQSKLVEQLYDDSLNSTGSLGDASKQLLQTRDRQESSRKFLVFFIMAGLSILFLEYY Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2731.fasta_al_trimmed; alignment length = 88] Allma1 ---------------------------------------------------------------------------------------- Ashgo11 IHPKGRKLQQLNKATIRDE-KIFTHEQCLLLIREFIGRDDDELEELKRPPTSRHQLLEAKKRLELEEL--RT-GFCPDLTNVAFLRRW Aspfu1 LHENSRDAKRLRRANARDD-RVFSEDDMKDLVARYINRSVPEIEQLQRPPSKREEALLQRTEVENKEF--KT-GFMPDLSVIKGLASW Aurde31 FHPESRKAGQLARTALRKA-KLMSLPELHALVDVWLTRHDEELEQERRPQSARELALEQTKQLEAEEY--RT-GIVPDLTNVALFRRW Batde5 AHPYSRKALQVQRALHRDT-ELITEADVHSIIDMYINRNEDEISQIMRPKPGRLGILESLREKDLAEY--NA-GIIPSLTNVEMLKNW Botbo1 FHPHSRKAGQLERASLRKT-KLISLPELHLIVKLWLTRHDSDIELEQRPKSTKETKLLEVKLQDQEEY--RS-GIVPDLTTVELFRKW Botci1 LHEGSRDSLSLRRAGGRDD-KLLELDAIHSLIKTFVHQNDEELNAIKRPASTREDLLKIKIAADEKEY--EN-GFLPDLTNVMAFALW Caeel ---------------------------------------------------------------------------------------- Canalb1 LHIKGRKFKQLNRATLRDK-KLFTLDEMKQIIEKFIHQNDDELQRLQRPPTNRQTILEEKLKYDLEIY--RT-GFIPDLTTVERIKEW Cangl ---------------MRES-KVFSYEEAAVFIEQFINRDDPELEQFKRPTPNRQLLLEQKKKLEMEEF--KK-GFCPDLASVVFLRNW Capow IHPESREAKRMARSVLRLN-RVVLEVEMHVLIQAYLRRNDQEIRQEHRTKAAREDALDARIASETAEY--NS-GFAPDLTTLELVKNF Catan2 ---------------------------------------------------------------------------------------- Cioin LHPNSRTALNIVQQSRRHNLKLYSKFEYTELVERYFTRFNDELEQIEIQHGARERSIKLAQEHELMLF--NSTGLLPDVFNFREFMEW CocheC53 LHEGSRDTKRLQSAAQRDD-KLLSVAEVQAMIEDYVGRDDEELAKLKRPPSTRQNLLEINQKTERDEY--AS-GFVPDLENLRKLKEW Coere1 ---------------------------------------------------------------------------------------- Conco1 AHPYSRKANQIQRAIDRSI-KVATMEEVHDLIQTYLDRNEEEL----NSKSFQADMIKLQHAKELKEYE-VE-GFVPDLTNVKLLREW Conpu1 FHPDSRKAGQLNRVQIRKN-KLMSLEQLHSVIDVWLPRHDVELTRERRPKSARESFLEDAKHQEEEEY--RT-GIVPDLTTVELFRNW Copci FHPSSRKAGQLARKALRKE-KLLTLEELHGIIDVWLTRHDKELEEERRPKSTREVHLEDLKMRETELY--RT-GMVVDLTTVELFRQW Croqu1 -------------VALRTE-KLCSLEELHQLVQDFIQRHSVDLENERRPKSSNQERMEIDQEIEEAEY--KT-GFLPDLTSVKLLRQW CryneH991 LHPGSRKAAQLTRVQLRVE-KLLTLPSLKALIEVYLKRHDPRIEELTRPKPKELLDLEEVKKRETGEY--ET-GMVPDLTTTLLIHSW Crypa2 LHEFSRNSKRLHKAQVRDE-RLFDMDKTQAFISQYVHQYDEQYDAVRRPASAREDLLKMKVDALEKEH--QN-GFVPDLSNLDLLDRW Debha1 MHVKGRKFKQLNRATLRDQ-KIFLLEQMKSFIEDYIGRNDEELKQLKRPATSRQLHLEVVIGDEKQVY--ST-GFIPDLSTVERVKLW Dekbr2 LHPNSRRAKRLARATLRQE-KIFTVDEIKGMLQTFICRDDDELEQLKRPPTKRQELLELKKDAEVKHF--ET-GWLPDLTNVKIFRGW Dicdi LHPLSRKAKKLTLEGIRDI-K-FTESEVSDIIDQFLKTKTP---EEETSRTNKLEFTKSQHNDEIKEFK-NN-GYVPDLTYVRFLLNW Dmel -HPNSRKTKALGKKARRQN---LRPQELEDLIELYFTRFDEELEQINNQHAARKDVITMTLEKERNEF--RTGGLLMNLCKLKMLRDW Enthi EHPNSRKAKRKAKEEQRDT-KLVTQEELFVLSVNYCCRKDVEYDDIDSIQNKRDRILEEISNMRKALIG----GVIPDLLNIKFILTV Falba AHPNSRAAAKFSRSSQRNN-KLITLEDMDAMITSFISRHVDSARPVASAADSRATLAAATIKANEASC--RA-GHVPDLFACRAFLLW Fomme1 FHPNSRKAAQVERAQLRKS-KMLTLEELHDLIDVWLCRHDLALETERRPKSTKEIALEALKEREVDEY--RT-GLVPDLTNVELFRLW Fusgr1 LHEKSRDSMRLHKAGVRDQ-RI-EIEEVQRMIHNFVHQHDEEYDAVKRPASVKEDLLKAKINLLEEEY--KG-GFIPDLLNVNVLLLW Galma1 FHPSSRKAGQLARHALRKG-KILLLEDLHSIIDVWLTRFDDELQAEKRPKSSKENKLEETKLRETEVY--RT-GMVIDLTTVEIFRRW Ganpr1 SHPLSRKQNQLRRATLRQD-RLFSKADFHELVDSYLRRNDDEIAEHEGSKSKRLDAIEAMRKREFSEYEGIG-GLVPDLLNRSILARW Gloin1 IHPSSRKAAQLQRISLRKD-RLATKAEVYDLIEMFINRNDDEILRLKKVNSSKYFYLESLKLKEKKEY--IE-GFIPDFMNVKLLRQW Hisca1 ---------------------------------------------------------------------------------------- Klula1 VHPKGRKFQQLNRATLREE-KVFDYKETAVLIQEFIARDDNELNELKRPPTGRQQLLQHKRDLEMEEF--KS-GFCPDLTNVIFLRAW Lacbi2 YHPSSRKAGQLARHALRKG-KLLTLEELHHIVNVWLTRFDEELEEEKRPKSSREVYLEDLKLREAEEY--RT-GMVIDLTTVEVFRRW Lenti61 FHPQSRKAGQLVRTQLRKS-KLLSLDELHFVVDIWLARLDSELDAEKRPRSLKEQKLEEQKLRETELY--RT-GMVIDLTNVELFRKW Malgl1 MHPNSRHAYQKARVMLRQR-RLPDLYSFHDFMTFFLARHDQELAALQRAKSKRLAELENLIASEKREY--HD-GIVPDLCNVGLLRQW Mellp23 LHPHSRRAKQICRVALRTD-KLCTLPELHQIVQDFIHRHSAELESERRTKSVAQERIEIDQETEEAEY--TT-GFVPDLTSVKLLRQW Mnele ---------------------------------------------------------------------------------------- Monbr LH--------------RDD-RMYEHHEVVAMIERYLHEREQEVQALEKGKSATAIGLRSRLDTNRGEFKSQG-GFAPDLTVVHRLSEW Morel2 IHPSSRKAQQVMRVVLRKD-RLLTREEQHALIEEYLARYNEEYNSLVRPKAAREDMLAAFIANERREY--AS-GFIPDFSNVTILREW Mucci2 IHPYSRKAHQISRVYQRKE-KLATKPEMHELIELYLERHDDEINELEKPKNARQQLLESIKAREASEY--IS-GMLPDMTTLKLLRDW Mydma IHPNSRKASQISKSIHKQE-KKYSLIEVSELILKYINRFEKRIDEIEQAHSAEYSALKLVREKETNLI--NDGCFAPDITVVKVLRDW Neucr2 LHAKSRDSRRLHKAQVRDD-RLLELSAIQKKIAEFCHQHDEEYHEMKRPPSAREDLLRMKMEALHKEE--RD-GFLPDLTTTEMLDRW Orpsp11 AHPYSRKAHQVQRAMLREE-KYLTLEELTNTIERYINRNDEEIENITRPTPQRLTLLK------------------------------ Pench1 LHENSRDAHRLRKAGARDD-RLLSTEEISEFVAKYIARDAEEIKQLERPPSKREEALKQRVQTEDREF--AT-GLMPDLSAMTAMKNW Phybl2 CHPSSRKARQLTRVFLRKE-RLATMKEMHDLVEMYLERNNDELAKLVRPKTKRELLLLALIESERAEY--KS-GFVPDMTTLKLLRDW Picst3 IHIKGRKFKQLNRATLRDK-KLFSLAEMKAFVELFISRFDDELQQLRRPQTNRQQILEEKVKYDKRIY--AT-GFTPDLTTVERLRLW Plicr1 FHPESRKAGQIARSQLRKG-KLMTLEDMHSLIDIWLTRHDDELEEERRPKSTAEVKLEERKLIESEEY--RT-GMVIDLTNVELFRRW Polpo VHPLSRKAKKITKAGFRVV-R-YTPRELSRWIEEYINRNDDLLGEDEVNRSNTADLLNSLKVDELKQFN-GD-GYIPDLTNVKWLNEW Pucgr2 LHPHSRRAKQITRIALRDD-KLADLSTLHVLITSFIARNSSLINEETRPKSTALEKLESLRRSELIEY--STNGFIPDLRNLKLLDQW Punst1 FHPQSRKAGQLARTQLRKD-KLFTLQELHEIIDVWLTRHDAALDQERRPKSTGELKLEEIKLRETEEY--RT-GMVPDLTNVALFRAW Rhior3 IHPYSRKAQQLSRVYQRRE-KM---------IELYLARHDEEIEQLEKPKSPRQDLLEALKEREANEY--VS-GLLPDLTTLKLLREW Rhoto1 VHPNSRRAKQLQRVELRAK-KLVSLPDLHQILNDYLNRNEAELKHEREGKGKRETELEKLREEEESEY--KT-GFLPDLTNVVICRQW Rozal11 ---------------------------------------------------------------------------------------- Sacce1 VHPKGRKYEKLVRATMRED-KIFDHAHTREFIQSFIERDDTELDELKRPPSNRQVLLQQRRDQELKEF--KA-GFCPDLSNMEFLRNW Salro VHPESRKAKRMNKQYLRKA-KL-TQDQLRQLTQEYVKRFDD---EIAQNKSKHRQMMLSERSSHEKSLF-QS-TYVPDLTNVR----- Schco3 FHPESRKANQIARKALRKG-KMLTLEELHAVINVWLTRHDQELQEEQRPKSAKEIKLEDLKLQESEGY--RT-GLVIDLTNVKVFRQW Schpo1 ---------------------------------------------------------------------------------------- Sorma LHAKSRDSRRLHKAQVRDD-RLLELPAIQKKIAEFCHQHDEEYHEMKRPPSTKEDLLRMKMEALHKEE--RD-GFLPDLSTTEMLDRW Sphar LHPASREAKRQSRAMLRKE-NLYTDADMCKLIELYASRHDAELAAIAGPKNNRQMVLNLCKTEEFAAL--NGNGFAPDLSKTQRWRDW Spipu1 AHPYSRKAVQMRRAINRQD-KLATNELVHDIIEQYIARNEEEIAEIRRPRPSRLDLLENLKSKDEQEY--IN-GIIPVLTNVTILRSW Sporo1 IHPNSRRAKQLQRVELRSK-KLISLPELHQTLQDYINRNESELAAEREGKGKRETELEKQKEDELNQY--RV-GFLPDLTNVVLCRQW Stehi1 ---------------------------------------------------------------------------------------- Tapde11 AHPNSRKSHQIQRAALRDE-RIFTEEEVKSLIETYIERNKSELMTLVRPKSSRQDLLERAKELELSEY--RS-GFVPVMDNLEELRHW Thetr ---------------------------------------------------------------------------------------- Treme1 VHPGSRKAGQLARVSLRTL-KLLSLPSLRALIDVYLARNDARLHELERPKFKELVDLEEIKRVEWAEW--ET-GFVPDLTTVRLMYSL Trire2 LHEKSRDSLRLHKAGVRDQ-RLLEVSAIQALIHTYVHQYDEEYDAVKRPASTKEDLLKIKITALEKEY--QA-GFIPDITSVKSLDAW Umbra1 MHPSSRKAFQLTRVVMRND-RLANSEELHSLIDMYLSRNDEELEKLQRPKSSRQDMLEALVKREHDEY--SK-GFLPDLQNVKILRAW Ustma22 THPYSRRATQLARVAHRKD-KLPDLASVHAFVDTFLTRHNDELQELQRPPHKREIELKETIAKELQEY--NE-GILPDLTNVKLLRDW Walse1 IHPGSRKAEQVTRVNLRLN-KLLSLEDLHNLVELYINRDDDHYNELRSGKSARESELESRKERDLQEY--AS-GFVPDLSTMKLFKQF Zygro1 VHPNGRKHKQLTRATIRES-NIFSLEETAVFLQEFIQRDNEELEELKRPPSNRQLLLQQKYDREMEEF--KK-GFCPDLTNVVTLRNW [Cluster2734.fasta_al_trimmed; alignment length = 132] Allma1 ------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 LNQSKLGTREYWDEFYAVEQRNFDAQDTGFDEDRAAERMVEFLVLDVGC-GNGHLLFALADGVDYSERSVQLARAIGATHVVLDKGTLDAIALSVERVL-AGGVLLITSCNFTEDELGGKKGSTICSVAFTK Aspfu1 LSPSELGTKNYWETYYARTLAHLDDDDPGFSEHKAPEKVLRFLILDLGT-GNGSMLALLRKGVDYSARSVELARELQRLKIVLDKGTFDAVSLSARRLV-RGGFLVVTSCNWTEEELGGQEGQGVCTVCFQR Aurde31 FKPSKLGTKEHWDSVYQEEIENFELGEEGFGT-ETVEKMVEWAILDIGT-GNGVMLFSLADGVDYSEDSVKLARLVAGARLLLDKGTYDAIALAVARLL-KAGLFLITSCNFTEEELGGRSGSVCASVAFQK Batde5 LCSSKLGTKEHWDSVYNTEVENFDHGEEGFGE-DSVDKMVTWAVIDLGC-GNGHLLFRLEDGVDYSKESINLSQKIGSSHLALDKGTLDAISLCVAAMI-KGGVLLLTSCNWTEAEIGGAVGQTITSVALRR Botbo1 LQPSELGTKEYWDQVYEEEVNNFEFQDEGFGL-ESVEKMVDWVCLDIGA-GNGILSIALAEGIDYSADSVRLARLVATQRLLLDKGTFDAIALAVALLL-KGGYFLITSCNFTEGELGGKSGSVVCTVAFKR Botci1 LDPSALGTKEYWDNLYNREISNHDASDVGFDDSSAEDKVVDFLLLDLGT-GNGHFLVRLREGVDYSERSIEFAKRIAKDKIVLDKGTFDAISLSVLALV-RGGVAVVTSCNWTEEELGGVKGQTVCSVCFRK Caeel IASSQLGTKDFWDQRYELELKNFQHGDEGFGT-SSETRIVKYLILDLGC-GNGSVLRKLRSGVDYCQKAVDLSAAASKAEVILDKGTWDAMSLSLDNGL-SGGRFVIFSCNFTFDEMGGKQGVTSTGAVFRK Canalb1 LNSSKLGSKEYWNNFYKKEQDNFNEEDTGFDDSDAESKMIQFIFLDLGT-GNGHLLFQLSEGIDYSPDSVKFASGVAKRKILLDKGTLDAIALNVEKMM-VGSILLITSCNFTKDELGGVKGSTVVSIAFVR Cangl LNTSKLGTKEYWDDFYALERQNFNPEDTGFNDNDAEEKMVEFLMIDLGT-GNGHLLFALTEGVDYSEQSVKFANEIVANKVVLDKGTLDAIALSVERLM-EGSVFLITSCNFTQEELGGVKGTTICTVAFVK Capow PEPSKLGTREYWDQVYEREVGNFERGDVGFGM-DAVESVVDWIVVDIGC-GNGVSLVELARGIDYSEPAIELARKVAAADLCIDKGTYDAISLAVHALC-STGLFIITSCNWTNDELGGKKGSSISTVIFAP Catan2 ------------------------------------------------------------------------------------------------------------------------------------ Cioin LPSSVLGTYDHWDEVYKDEMKGLEMDDPGFGR-SATNRVVRWIILDVGC-GNGLLLLALAKGLDYCQSALDLASAVFKKEVCLDKGTYDAVSLNMATLM-NSSVFIITSCNWTTSELGGKSGKTVSTCVFKK CocheC53 LDPSELGTKSYWDAAYTTERKNFNASDEGFSDAGAEERMLSFLFLDLGT-GNGHLLFALREGVDYSTESVTLATSIRDAKVVLDKGTFDAICLSVEPLV-KGGRFLITSCNWTEEELGGKTGSSVVTLCFKR Coere1 FKASRLGSKDHWDSVYMREIVNYESGDTGYGE-ETAEKLVKWVILDVGC-GNGHLLVKLATGTDYSLQAVELAQSIAKGSVVLDKGAYDAISLMVVASL-KGGILLLTSCNWTEDELGGVVGQTVVTLAFKK Conco1 ------------------------------------------------------------------------------------------------------------------------------------ Conpu1 ------------------------------------------------------------------------------------------------------------------------------------ Copci LPPSKLGTKEHWDQVYERELTNFEIGDEGFGE-DSVEKMVDWAILEVGS-GNGTLLFGLHEGIDYSMGAVKLARGIAVQKLLLDKGTYDAIALGVVRLL-KGGIFLITSCNFIEDELGGHSGSSVVTVAFQK Croqu1 LPPSKLGTHEYWDLTYGRELESFDIGDEGFGE-VSSDEILDWIILDVGC-GNGQLLFLLAQGIDYVASSIELTSRIAKSKLITDKGTFDAICLSISNLLAKGGIFLITSCNWTEQELGGTQGTTITTIAFQL CryneH991 LPPSKLGTKEHWDGVYKREVNVFDIGDEGFGE-DSVRKMREWAILECGS-GNGTLLLSFLIGIDYCEPAKVLAEGVEAAKLVMDKGTYDALCLSIAKLV-KGGFFLITSCNFTEEEIGGKKGSTVCTVAFQK Crypa2 LDPSELGTKEYWDSLYTTELTNHNPSDRGFDDSDAEAKLLEYLFLDLGC-GNGSLLLALRDGVDYSDKSVALARQVAQAHVVLDKGTFDAISLSVVRLV-RGGLFLVTSCNWTEEELGGVKGQTISTLCFQR Debha1 LNSSKLGTKEYWNSFYKKEIANFNEEDTGFDDSDAELKMIQFLIVDLGT-GNGHLLFQLHEGIDYSPDSVEFATKIAKQKILLDKGTLDAIALNVSQLM-HNSVLLITSCNFTESELGGVKGSTICSIAFIK Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------ Dicdi VESCVLGTKGHWDSAYDRELDCFETGDVGFGK-SCLKTMCKGVIIDLGC-GNGMTLIELSKGSDYSDKGIELAKRIMEQEAVLDKGTFDAIALSVEHIL-KDGIFVITSCNYTENELGGSKGTTQTTLIFKK Dmel LNGSELGTKEFWESSYNREIRNYSHGDVGFDE-SAQWRTIDWLVLDLGC-GNGMFLVGLANGVDYSPKAVELAQNIAEDNVVHDKGTYDAVSLCVEKLL-RDSLFVITSCNWTEDELGGKVGNVVTSIVFKR Enthi LPEERLSKKEFWEECYNRELENFNKNDIGFGE-DIAEQVVERLILDVGC-GNGYTLSLLGKGMDYSPASVKFTKKVLEQEIVIDKGTFDALMVALNQWLSKGGYFIITSCNWTEDELGGSQGSKTTTIFFKK Falba QNPSALGTKKYWDDQYKLELKNHSHGDIGFGE-QSATKMVTWCVMDLGC-GNGHMLFLMAAGCDYSPAAVELSRRLAAQIIVLDKGTYDAISLNLPMLV-SGGHFVITSCNWTTEELGGRSGQNVSSVAFRV Fomme1 ------------------------------------------------------------------------------------------------------------------------------------ Fusgr1 LEPSKLGTKQYWDDLYTNEISNHDPSDIGFDDSDAEAKILEFLFLDLGC-GNGSLLFSLRGGVDYSPQSIALARQITAT-VVLDKGTFDAISLSVLPLV-RGGIFLVTSCNWTETELGGHKGQTISTLCFRR Galma1 LQPSKLGTKEHWDSAYAEELEIFEIGDEGFGV-ESVEKMVGWAVLEVGS-GNGTLLFGLVDGIDYSAGAVKLSTEIAKTRLLLDKGTYDAIALGVARLL-KGGLFLVTSCNFTEEELGGKRGSICSSVAFRK Ganpr1 FEPSELGTKQHWDSVYEREVQNYEIGDTGFGE-DAVDKMVSWTIIDLGS-GNGHLLLELASGVDYSENAVTLASEVLSGTVAMDKGTYDAICLNVGAVL-KDGQFLITSCNWTQEEIGGVEGQRICTVAFTK Gloin1 YGPSELGTKEYWDSLYDRENKNFENGDIGFGE-NSVEKMVDWVILDIGC-GNGHLLLELASGIDYSSNAIKLARDIIKQRIILDKGTFDAITLYVHSLL-NNGYFLITSCNFTKEELGGVKGQTISTVAFKP Hisca1 LEPSQLGTKEYWESFYENSLSHLDDSDPGFAEHNAPEKVLRFLILDLGT-GNGSMLALLRDGVDYSSKSIELARQLRHGSIVLDKGTFDAISLSVRGLV-V-------------------RGRG-------- Klula1 LNTSKLGTKEYWDDFYSLEKQNFNPEDTGFADNDAEEKMVEFLMIDLGT-GNGHLLFTLLEGVDYSEKSVEFAAEILKTKVVLDKGTLDAIALSIEKIL-GNSILLITSCNFTEEELGGVKGTTICSVAFLK Lacbi2 LQPSKLGTKEHWDSVYEEELANFEIGDEGFGT-ESVEKMVEWAILEVGS-GNGTLLFGLLDGIDYSRGAVSLAKEIANKRVLMDKGTYDAIALSVTRLL-KGGYFLITSCNFTEDELGGKSGSICSSVAFRK Lenti61 LQPSKLGTKKHWDDVYSSELANFEIGDEGFGE-DSVEKMVDWAILEVGA-GNGNLLFALCEGIDYSADAIRLAEAIAKTKLVLDKGTFDAIALAIGRVV-KGGYFLITSCNFTEDELGGKSGNVYSTVAFRK Malgl1 LPESKLGTKEHWDQVYE------------FGE-DSVERMIRYLILDVGT-GNGHLLFALMDGIDYSAASIELSKAIGSKRIVCDKGT---IALSVHRLT-RGGIFFITSCNFTQEELGGQQGSTVTTVAFRR Mellp23 LPPSKLGTHEFWDLTYGRELESFDIGDEGFGE-DSSDEILDWIILDVGC-GNGQLLFLLAQGIDYSAGSIELTSRIAQAKLITDKGV---------------GIY--------------------------- Mnele LNDSHLGQKEYWDKVYVTELDNFNQDDVGFGE-RTEQKLVDWLLADIGT-GNGHILSLLAEGIDYSASSIKLAETINSDYICIDKGTYDAISLAIHSMT-RAVTTLIVACTYEEGDLFGIEGRRKV------ Monbr ------------------------------------------------------------------------------------------------------------------------------------ Morel2 FKPSKLGTKDYWDKVYNREVINFDHGDIGFGE-DSAVKMVDWVILDLGC-GNGHLLLDLAEGIDYSPAAIELAKAVAEDKVMLDKGTYDAISLHVASMM-RDGRLLITSCNWTQPELGGVKGQTISSVVFRK Mucci2 FEASKLGTKSYWDTVYDRENDNFEIGDIGFGE-DSVERMVEWVMIDLGC-GNGHLLLELSNGIDYSESAITLAKSVAKQRVVLDKGTYDAISLHVYRMM-DKGLFLITSCNWTKEELGGHEGSKICTVAFEM Mydma FGCSSRKKKGDCLSFYRNPFGTTEKERRSWSEKQIDARICSLHIVDKGIQANEEEITSLIQGIDYSQNAVDLSISIALSQVCHDKGTYDAISLRLSKIS--KSLFVITS--------GGKSGSTVSTAIFCK Neucr2 LEPSKLGTKEYWDALYTREISNHNPSDEGFDDSDAENKIVQFLIMDLGC-GNGSLLFALHDGVDYSEQSVELARRVLRTRLVLDKGTFDAVSLSVLQLL-RGGFFLVTSCNWTEEELGGVKGQTISTLCFQK Orpsp11 -----------------------------------------------------------AEGIDYSEYSIELSRKIAKKEIILDKGTYDAISLNVKQLMNKDSVFLITS----------------------- Pench1 LSPSELGTKDYWESYYARTLAHIEEDDPGFSEHNAPQKVLHFLVLDLGT-GNGSMLALLKKGVDYSRQSVELARELQRVRIVLDKGTFDAVSLAARQLV-RGGFLIVTTCNWTEEELGGHEGQGVCTVCFQR Phybl2 FEASKLGTKSYWDNVYDRENDNFELGDIG--Q-DSVERMVDWAVIDLGC-GNGHLLLALSEGIDYSESAIVLAKSVAKDRVVLDKGTYDAISLNVHRMI-SDGVFLITSCNWTMEELGGQTGSKICTVAFSP Picst3 LNDSELSSLAYWDNFYAREKKEMNDDFVGFDENGAEEKMVDFLVLDIGT-GNCHLLVSLADGIDYSPNSIEFAQAIVDRQVLLDKGTLDAIALSVVQLM-HDSLLVITSCNFTEAELGGTEGTTITTVAFKK Plicr1 LQPSKLGTKEHWDDVYKEEVVNFELGDEGFGP-ESVEKMVDWTILEIGS-GNGTLLFALAEGIDYSQGAITLSRSIASTRAVMDKGTFDAIALGVAPLL-KGGHFLITSCNFTEEELGGKSGSICSSVAFQK Polpo VESSKLGTKEHWDECYDREINCFDTGDVGFGE-TCLKKMCKDIILDIGC-GNGYTLVELSQGSDYSAKAIDLSKQIAESEVVVDKGTFDAMALSVSKIL-KGGYFIITSCNYTNAELGGSQGQSQTTIVFLS Pucgr2 LVPSRLGTQAYWDDNYGRELSNFEAGDEGFGE-ASSDEILDWIILDVGC-GNGQLLFLLAQGVDYSASSIELTSQIARAKLITDKGTFDAICLSIFDLLVKGGIFLITSCNWTEEELGGSKGSTITTIAFQT Punst1 LQPSKLGRKDHWDNIYSKELQNFEIGDEGFGE-DSVEKMVSWALLEVGS-GNGTLLFAMCEGIDYSADAVKLARAIAPTRLIMDKGTYDAIALGLANLL-RDGFFLITSCNFTEDELGGQSGQTISTVAFYK Rhior3 FEASKLGTKSYWDTVYDRENENFEIGDIGFGE-ESVERMVEWIIVDLGC-GNGHLLLELANGIDYSESAVVLAKSVAKERVVLDKGTYDAISLH--------------NCNWTMEELGGQTGSKICTVAFQP Rhoto1 LPPSKLGTRDHWDEVYEREVKMFEIGDEGFGE-DSAQDMVEWAILDVGT-GNGQLLFAFSSGIDYSPLSIELANNILTARLVTDKGTYDAVCLSVAKLL-PGG-------NWTQAELGGSTGSSITTVAFEK Rozal11 ------------------------------------------------------------------------------------------------------------------------------------ Sacce1 LSTSKLGTKKYWDELYALELENFNPQDTGFSDSDAEQKMIDFLVVDLGT-GNGHMLFELHQGIDYSEESVKLASNIAEATIVLDKGTLDAISLSVERIL-KDGIFLITSCNFTQDELGGVQGATICSVAFVK Salro ------------------------------------------------------------------------------------------------------------------------------------ Schco3 LQPSKLGTKEHWDNVYSSELANFEIGDEGFGE-ESVEKMVDWAILEIGS-GNGTLLFALAEGIDYSADAVALAKSIAQARLVLDKGTYDAIALGAARLL-KGGFFLITSCNFTEEELGGQSGSVVCTVAFRK Schpo1 LPESKLGTKQYWDNVYEREVSNFEFNDEGFGE-EAEERIVQWLVLDLGT-GNGHLLFRLLEGVDYSEAAIVLAKNIARHRLILDKGTFDAISLSVRGML-SNGIFLITSCNWTIQELQGSTGSSTSVIAFQI Sorma LEPSKLGTKEYWDALYTREISNHNPSDEGFDDSDAENKIVQFLVLDLGC-GNGSLLFALHDGVDYSAQSVELARRVLRTRLILDKGTFDAVSLSVLQLL-RAGF------SW-------------------- Sphar ------------------------------------------------------------------------------------------------------------------------------------ Spipu1 ------------------------------------------------------------------------------------------------------------------------------------ Sporo1 LAPSKLGTKEHWDEVYDREVKMFEIGDEGFGE-DSAQDMVEWAILDVGT-GNGQLLFALSSGIDYSSLSIQLAQSILESRLITDKGTYDAVCLSIAKLL-TDGIFLITSCNWTQAELGGSTGSSITTVAFEK Stehi1 PQPSKLGTKEHWDSVYEREIANFETGDEGFGE-DSVEKMTDWVILEIGS-GNGTLLFSLVEGADYSPDAVKLSRMIAASRLLLDKGTYDAIALGAASLL-KGGYFLITSCNFTEAELGGKSGNVYSSVAFTK Tapde11 LNPSVLGTKEYWENIYRRECANYNQEDEGFGE-ESEDKIIKYLVLDLGT-GNGHLLFTLHEGIDYSEASIALATAILRTKLVLDKGTFDAISLSVVRLM-KDAKLIVTSCNWTREELGGRKGYSTSQVVFTK Thetr PESSWLSTAAYWDAVYTTELARVGSGELGYGS-EPVALIVSLLLLEAGC-GNGHLALVLAAGADRSRPAINVAKVLRARLVVIDKGSLDCLVMEVAERL--GGYFVLVTIAVSRSELSASDAARNATALFAA Treme1 LPPSKLGTKDYWDAQYEREVTVFDIGDEGFGE-SSVKKMRKWAILECGS-GNGTLLLSFLTGIDYSPTAILLSQKVEHARLVLDKGTFDALCLSIARLV-KGGFFLITSCNFTEEEIGGKSGTIVCTVAFQK Trire2 -----------WDKLYATELTNHNPSDTGFDDSNAEGRIVAFLILDLGC-GNGELLFALRDGVDYSAQSVELARRIDATRIVLDKGTFDAISLSLLQLL-NGGIFLVTSCNWTEKELGGMKGQTISTLCFRR Umbra1 FKASQLGTKQYWDSMYVRENVNFEIGDIGFGE-DSVEKMVDWVIIDLGC-GNGHLLLALAEGIDYSPSAVQLAKSVAKQRIVLDKGTYDAICLDVRQMM-GEGSFLITSCNWTREELGGQTGSKICTVAFTP Ustma22 ------------------------------------------------------------------------------------------------------------------------------------ Walse1 LPSSKLGTKEHWDEVYEREVENFEIGEEGFGE-DSVEKMIDWAVLDMGT-GNGHLLFELVSGVDYSPASVKLSNQIAKSKVVMDKGTFDAICLSAAELV-KGGKLLITSCNFTEEEVGGSKGSTICTVAFER Zygro1 LNKSKLGTKEYWDEFYALEKNNFNPEDTGFDDNDAEAKMVSFLICDLGT-GNGHLLFELVEGVDYSEQSIEFAKEVAQTKLVLDKGTLDAIALSVEKLL-VGGVFLITSCNFTESELGGVQGTAICSIAFVK [Cluster2735.fasta_al_trimmed; alignment length = 269] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 DISHRRFNPLRGSYVLVSPHRTKRPWQGQQEPAYDPACYLCPGNKRAQ-GNPKYEKTFVFVNDYSAVFLKAEPVTGKCYVLTFSAAHNLTLADLEIIPVIDAWRYMQIFENKGAAMGCSNPHPHGQVWTTSSLPEEPAMELEQMKKYLLEDYAALESENQAFLVVCPWWATWPFETMIVS--KKHKRALVDLNENEQLAEAIAEITRRYDNLFETHFPYSMGIHQAPLHLHFYPPLLRSATVRKFLVGYEMMAEPQRDITPEQAAARLR Aurde31 --PHRRYNPLLGEYVLVSPQRNKRPWQGQVDPDYDPKCYLCPGNARSGKTNPKYTTTWTFPNDFPALLLKGEPVTGACDVIVYNPQHNLLMARMQIRAVITEWGHVQIFETRGAMMGSSNAHPHGQAWSTSSIPTEPATELRSLHKYLLCEYASLELSNEHWVCVVPWWATWPFEVLLLPH-HRHVLSIDELDEAESFADALSRLTVRYDNVFRTTFPYVLGIHQRPLHLHFYPPLLRSATVRKFPAGFEMLAEIQRDLTPETAAQRLR Batde5 DCSHRRFNPLNGSWVLCSPHRAKRPWLGHIEPSYQPDCNLCPNNRRVN-GNPDYSAIMVFDNDFPAILFQIQPVAGYARVLCFSPNHNLTLAEMSIGVVIDAWKHVQIFENKGDTMGCSNPHPHCQIWGTDYIPNEPSKELACMKAYLLCDYIHSEIQTDYFVCLVPFWAVWPFETLIVA--THHVGQLSDLDQHVDLAKMIKALTCKYDNLFQVSFPYSMGVHQSPLHLHFYPPLLRSASVRKFLVGFEMLAEAQRDLTPETAAAKLR Botbo1 AHPHRRYNPLTGEHVLVSPHRNKRPWQGQTEPTYDPQCYLCPGNKRSG-GNEVYDSTLVFSNDFPALLLTTQPVQGACDVLIFHPRHDLTLARLEIVRIVEEWKYVQIFENKGALMGCSNPHPHGQVWSLSVIPGIPATELGSLSRYLLCEYAHFEVKNEDWVAVVPWWAVWPFEILLLPY-KRHIPSISHLTGDESFAQILSAVTIKYDNLFRTSFAYSMGVHQKPLHVHFSPPLLRSATVRKFLVGFELMAEPQRDLTAEQAAGRLR Botci1 ---------------------------MAQEPEYDAACYLCPGNKRAQ-GNPQYKDTFVFVNDYSAVLLRAEPVTGKCYVLTFSPSHNLTLADLQILPVIQTWKWMQIFENKGAAMGCSNPHPHGQIWTTTGLPEEPASELVNLLKYLLEDYVKLEMQNDSFLVVCPWWATWPFEVMIIS--KTHKRGLVDLNDAEGFAEAVAEVTRRYDNLFETSFPYSSGIHQAPLHMHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAAAKLR Caeel QNNFRRYNPLIDEWVIVAVNRINRPWQGAKTTEQSILNPLAPGGTRSS-GNENYVSTYVFDNDFPSFLFKQHEVKGVCKVICYHPNSQLTLATMEVRVVIDIWEWVQIFENRGAVVGCSNMHPHGQLWASNYLPTLPMKKHESQKKHMLMDYLEQETRNEHWTWLVPYWAFWPYETMLLP--NRHVERFTDLGEVESLSEILRSLLIKYDNVFECSFPYMMGWSGAPLHLSFFPPLLRSATVPKFLAGYEVFAEKQRDLSPEIAAKTLS Canalb1 NHSHRRLNLLTNKFVLCSPHRAKRPWQGAKEPEYDPKCYLCPGNIRAT-GNPKYDATYIFPNDYPAVLLQTQGVRGKCFVICFSPKHNLTLPLMEINNVVNAWKYLQIFENKGAAMGCSNPHPHGQAWCLDVIPTEVKDELDNMSEYLLGDYVELELENDSFIVVVPYWALWPFETLLIS--KTHLKSIQEFNDKQDLAAILKILTTKYDNLFNTSFPYSMGIHQAPFHMHFYPPLLRSATVKKFCVGFEMLGEPQRDLTSEQAAARLQ Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow DHPHRRLNLLNGKWILCSPHRAKRPWQGQQEPEYDPNCYLCPGNKRVT-GNDKYEHTFAFRNDFSALLLVAQSTRGRCHVMCFSPKHNLTMAQMEITGVVHEWEYTQLFENKGEVMGCSNPHPHGQVWASDTVPEEVSQEVASFRLHLLCDYLALELENDSFVVLVPWWAYWPFETLVLP--RTHTSSIAQLDEKQDLAAILQKLTCKYDNVFECSFPYSMGIHSSPMHMHFYPPLLRSASVKKFLVGYEMVADICRDITAEQAAERLR Catan2 -MSHRRRNPLTGEWVVCSPHRTQRPWKGASETEYDPTCALCPGNQRSG-GNPDYTDNWLFQNDFAALLFQSAPADGKCIVHCFSRRHDLTFADLQVTGVLATWEHALVFENKGAMMGCSMPHPHCQIWASQFVPTVVATELANMAAFMLCEYAQKEVQNTQFMAVVPYWATWPFEVLVLP--KTHVANLAELAAADLLAEVMSAVTRAYDALFQCSFPYSMGFHQDKLHAHFYPPLLRSATVRKFLVGFEMLGEAQRDLTPEDAAKRLR Cioin EHQHLRYNPLKDEWVLVSPHRLKRPWAGKVEPEYDLKNPLCPGNIRSS-GNEQYASTYVFNNDFPALLFKMAPASGECKVMCFHPHSNVTLPVMEILNVINEWKWIQIFENKGAIMGCSNPHPHCQVWASSFLPNEPRVSDKNQKSYMLVDYAARESENNHWIAVVPYWATWPYQTMLLP--KRHILRMTDLEDVESLAEAMKLLLTKYDNLFKVSFPYSMGWHGAPLHAHYYPPL-----------------XPQRDITPEKAAENLI CocheC53 DISHRRFNLLRGSWVLVSPHRTKRPWQGMQEPDYDPKCYLCPSNTRAN-GNPKFENTFVFVNDYSAVLLRAEAVTGKCYVICFSPSHNLTLADMQIVPIIETWRYMQIFENKGTAMGCSNPHPHGQIWTTTSLPEEPATELVQLSKYMLVDYAELESENESFWAGVPYWAVWPFEIMIVS--KQHKRSLVDFTKDEQLAEAIAEITRRYDNLFETQFPYSMGLHQAPFHIHFYPPLLRSATVRKFQVGYEMMAEPQRDITPEQAAERLR Coere1 DHSHRRFNPLTGSWVLCSPHRAKRPWLGQVEPEYDPKCYLCPGNKRAA-GNDNYTSTYVFTNDYAAVLFRVESTCGQCKVVCFSPRHDLTLPELQISQVVSTWGYIQIFENKGAMMGCSNPHPHGQVWAMSDVPSEPAAEIASFKAFLLCSYVYAEGQNETFMVVVPFWAVWPFETMILA--KSHIPHIGELSQLQHLAEAMQALTIRYDNIFQCSFPYSMGLHQSPLHLHFYPPLLRNSTVRKFLVGFEMMAEPQRDLTAEQAAARLR Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 SHPHRRFNPLTGSHILVSPHRTKRPWLGQTEPEYDPECYLCPGNTRVG-GNDKYTSTLVFENDFAAVLLTVEPVQGGCDVICFHPRHDLSFPTLDIEKVIDQWKYVQLFETKGAIMGCSNPHPHSQAWSLSVIPTLPEKELNALRSYLLCDYVHHEIKNNNWVALVPWWAYWPYEVMLLPY-KRHVPSLQHLTEEEDYAEIISRMTKRYDNLFSCSFAYAMGIHQRPLHVHFEPPLLRSASVRKFMASFEVMAESQRDLTPEQAAKRLR Copci ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 EHSHRRYNPLTREWVLCSPHRAKRPWQGQTEPAYDPKCYLCPGNIRVR-GNDKYGGTFTFENDYAAILYRTEMARGKCFVICFNPRHDLTIAELDILPIVDAWKYVQIFENKGAVMGCSNPHPHGQAWALSYIPTTAAKILGSQRAYLLLAYAQAELVSKYFLACVPYWALWPFEIMIIPQ-IHHIPSLFQLTADQDLAQIIGVVTRLYDNLFKCSFPYSMGINQSPLHLSFYPPLLRSASVKKFQVGFEMFAESQRDLTPEQAAQALR CryneH991 EHPHRRYNPLIGKHVLVSPHRTKRPWKGQTEPEYEATCNLCPGNERSN-GNPKYIDTFTFENDFPALLFASEPIRGRCKVICFHPRHDLTIARMDVVRVIGEWGYVQIFENRGAMMGASAPHPHGQVWSLSYVPDEPQTELNNLAASLLCTYAAEEVEESGWVAVVPFWAVWPFETLLLPY-KRHIPSLIQLNDNEGLARILQRLLVRYDNLFSCPFPYSMGLHQSPIHFHFYPPLLRSASVRKFLVGFEMMAEVQRDLTPEQAAARLR Crypa2 DISHRRFNPLTNSWLLVSPHRTKRPWQGQQEPDYDPKCYLCPGNERAQ-GNPQYKDTFVFVNDYSAVLLRAQPVTGKCFVLTFSATHSVTLADMEILPVIETWRYMQIFENKGAAMGCSNPHPHCQIWTTSTLPEEPGKEIVSMTKYLLADYVKLEIQNDGFVIVCPWWAIWPFEVLVIA--KRHVRALVDLTDEELFAEAVQEVTRRYDNLFECSFPYSSGIHQAPFHMHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAATRLR Debha1 NHSHRRFNPLSNTYVLCSPHRAKRPWQGAKEPSFDPKCYLCPGNIRAT-GNPKYENTYIFPNDYPAVLFKTQGVKGKCFVICFSPNHNLTLPLMDITSVIQSWKYLQIFENRGFAMGCSNPHPHGQAWCLDTIPTEVDHEIKNMTNYMLGDYVQLELENDSFIVVVPYWALWPFETLLIS--KEHLRSIKDFTEKHDLASILKKLTTKYDNLFNTSFPYSMGIHQAPFHMHFYPPLLRSATVKKFCVGFEMLGESQRDLTSEQAASRLQ Dekbr2 DCSHRRFNPLTGTYVLCSPHRAKRPWLGAKENTYEPGCYLCPGNKRAV-GNPKYSTTFIFPNDFSAVLLITKGVRGKCFVICFSPNHALTMPLLEIVGVINAWKYVQIFENKGAAMGCSNPHPHCQSWCLDTIPTEISRELSNLIKYSFADYIRLEQENDSFIVVVPYWALWPFETLLIA--KEHLRSLEDFDEKHDLASILKKLTVKYDNLFETSFPYSAGLHQAPFHAHFYPPLLRSATVKKFCVGFEMLAEPQRDLTSEQAAAKLQ Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel EHPHRRLNPLNGQWVLVCPHRTQRPWSGQQEPEFDPTNPLCPGVTRPN-GTPEYESTYVFENDFPALLFQIAPARGNCRVMCFHPKSNLTLPTMEIVVVIDEWAWVQIFENKGAAMGCSNPHPHCQIWSCSFLPTEPQLKQERLRAYMLADYVERELENRDWLVVVPFWATWPFETMLIS--RNNNKRINDLTAEQNLALTIKELTTKYDNLFQCSFPYSMGWHGAPLHAIYYPPLLRSASVRKFMVGFELLAMAQRDLTPEQAAQRLR Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 QHTHRRYNPLTDEYILVSPHRARRPWLGQIEPQYDPSCYLCPGNKRAG-GNDAYTSTYTFNNDYAALLLAYNSVHGECDVIVFHPRHDLTLARLDISIVIREWRYVQIFENKGAMMGCSNPHPHNQVWSMSDIPTIPAKEFASLLRYLLCEYAHLEVKNEDWVALVPWWATWPFEVLMLPY-RRHIHSLPDLTPTESFARILSEITLRYDNLFTCSFPYSMGIHQAPLHLHFFPPLLRSASVRKFLVGFELMAEAQRDLTPEQGASRLR Fusgr1 DISHRRYNPLTDSWLLVSPHRTKRPWQGQQEPEYDPKCYLCPGNPRAA-GNPKYERTFAFVNDYSAVLLQAQGVKGVCYVLTFSPKHHVTLADMEIVPVIEHWRYMQIFENKGAAMGCSNPHPHCQVWTTSTMPEEPGKELVQMTKYLLGDYVKLELENDAFVIVCPWWAVWPFEVLVLP--KRHIRSLLDFKPEEQFAEAIQEVTRRYDNLFECNFPYSSGLHQAPFHMHFYPPLLRSATVKKFLVGYELLAEPQRDITPEQATVRLR Galma1 THPHRRFNPLTNEYILVSPHRTKRPWLGQTEPSYDPSCYLCPGNSRTS-GNPEYKQTFVFENDFAAILMAAEPLHGACDVIIFHPRHDLAMPRLEIGQIIEEWEYVQIFENKGAMMGCSNPHPHGQAWSLSVVPTLPAQELRSLKQYLLCEYAQAELVNDHWMAIVPWWATWPFEILLLPY-RRHIDSMSALNKEELFADILSRVTRRYDNLFSCSFAYSMGIHQRPLHLHFDPPLLRSASVRKFLVGYEMMAEAQRDLTPEKAAERLR Ganpr1 EHPHRRYNPLTDTWVLCSPHRAKRPWLGQVEPQHDPTCYLCPGNTRSD-GNSDYTSTFVFTNDFAAVLLKVESVTGTCRVVCFSPRHDLTLAEMHIQEVVQTWNYVQIFENKGAAMGCSNPHPHGQIWATSDIPTEPARELASLAKYLLCNYVKLESSTEHFICLVPFWAVWPYEVILLS--LRHASTLAELTPAEDLADCLRRVTARYDNLFATSFPYSMGIHQAPLHLHWYPPLLRSATVRKFLVGYEMMAEAQRDLTAEQAAERLR Gloin1 ENSHRRFNPLTNSWVLCSPHRTKRPWEGHKEAEYDPECYLCPGNTRAQ-GNPQYENTFIFNNDFAAVLLRVEGVRGECKVMCFSPKHNITVAEMAILCVIQSWNYIQIFENKGSIMGCSNPHPHCQVWCTETIPEEPTKELISMNNYLLCDYTQLETENNSFVCLTPFWAVWPYETMIIS--KSHIISLLDLENDDDLANIIHRITCKYDNVFECSFPYSMGIHQAPLHLHFYPPLLRSPTIKKFLVGY--VKSNQLMINNNNIIIEI- Hisca1 DISHRRYNILRGSYVLVSPHRTKRPWQGQQEPVYDPACYLCPGNKRAQ-GNPQYKNTFIFLNDYSAVFLQAEPVTGRCYVLTFSASHNRTLADLEIKPIIDAWRYMQIFENKGSAMGCSNPHPHGQVWALSCLPEELTIELAQLQKYMLQDYATLEIENDLFLVLCPWWATWPFETMIVS--KKHRRALVDLTTAELLAESIAEITRRYDNLFETHFPYSMGIHQAPLHIHFYPPLLRSSSVRKFLVGYEMLAEPQRDITPEQAAVRLR Klula1 DHSHARYNPLTDSWILVSPHRAKRPWLGQQEPDHDDKCYLCPGTTRAT-GNPDYESTYVFTNGYPAVLFKLKGVKGNCYVICFSPKHNLSFPQMEIMNVVKTWKYLQIFENKGTAMGCSNLHPHGQAWCLDSIPSEPAKEFDHFEKYLLEDYVNLELENDSFLVVVPYWAVWPFETMVLS--KRRIPSLNQFTDKEDLASIIRNLTIRYDNLFETSFPYSMGLHQASFHMHFYPPLLRSATVRKFLVGFELLGQPQRDLTAEQAADRLK Lacbi2 DHPHRRLNPLTNEYILVSPHRIKRPWLGQTEPKYDPDCYLCPGNRRSN-GNPSYNHTFTFENDFAAVFLTCQPIHGACDVVVFHPRHDLTLSDLDIESVIDEWKYVQIFENKGAMMGCSNPHPHAQIWSLSVVPTIAAVELESLIKYLLCEYAHVELLNQSWVAVVPWWATWPFELIVLPY-RRHIPCLSDLDVAEALADIIARVSRCFDNLFSCSFPYSMGVHQQPIHLHFDPPLLRSATVRKFLVGFELMAEAQRDLTPEEAAVRLR Lenti61 THPHRRVNPLTGEHVLVSPHRTKRPWLGQTEPAYDPKCYLCPGNTRAG-GNETYEHTMVFENDYAAVLLTTEPVQGGCDVLCFHPRHDLTLARLDIVRIIEEWKYVQIFENKGAMMGCSNPHPHGQVWSLSAVPTLPATELANFQKYLLCDYVNFEVQNEHWVALVPWWAVWPFEIMLLPH-KRHIPSIVHLTPEEAFAQILSQVTIHYDNLFSCSFAYSMGIHQRPLHLHFAPPLLRSASVRKFLVGFELMAEPQRDLTPEQAATRLR Malgl1 ---------------------------------------------------------------------------------------------MHIVPVIHTWKYIQFFENKGQAMGCSNPHPHGQVWALDYVPCEPATEMQNMNEFLLLAYAHMELVNEDFVALVPFWATWPFEILLLPH-RRFIPSIQDLSHSETFATILGEITCRYDNLFQTSFPYSMGLHQRPLHIHFYPPLLRSATVRKFLVGFEMMAEPQRDITAERAAALLC Mellp23 EHPHRRYNPLIREWVLCSPHRAKRPWQGQTEPTHDPKCYLCPGNTRAQ-GNPHYTGTFTFE---VRTLFRTETARGKCFVICFNAHHDLTIAELEILPIVDAWRYVQIFENKGAVMGCSNPHPHGQAWALSYIPTISSKILDSQRAYLLLDYSQAELLSTHFMACVPFWALWPFEIMIMPH-KDHIPSLLHMSNDQDLAHTVGVVTRLYDNLFQCSFPYSMGINQSPLHLSFYPPLLRNASVKKFQVGFEMFAESQRDLTPEQAAHMLR Mnele -MATQRRNPLTGEWIIVSPHRISRPWGGEKS-----STYLSPGATRSN-GNPEYTSTFVFPNDFSALLFQSLPAGGECHVMCFSPHSDLSLPLMDIQLVIREWLYVQIFENKGAMVGCSNSHPHCQIWSSSFMPYLISLEDNHQREYLLVDYLEEELESAYWVALVPYWAKWPFELLVLP--KRHVTQLRQLSDEEDLSGTMKRYLTRXXXXXXXXXXXXXXXXXAPLHAHYYPPLLRSASVKKHIAGYEMLAQCQRDLSAEDAARRLK Monbr DHSHRRFNPLLDEWVLVSPHRMKRPWKGAIEPKHDPTNPLAPGGPRPG-GNPMYECTYVFDNDFPSLLMQLAGVRGCCRVMCFHPDSNVTLPLMEIRKVIDTWKWVQLFENKGQAMGCSNPHPHCQIWATGHLPNTAARKDQAQLAWMLMDYIKLELENEHWCAVVPWWALWPYETLVLP--KRHVLRLQDLTPEEACADITKRLTIKYDNLFQTSFPYSMGWHGAPLHAIYYPPLLRSASVKKFMVGYELHAEAQRDLTAEQAARKLR Morel2 HHSHRRFNPLTHSWVLCSPHRTQRPWQGKQEPSYDPSCYLCPSNTRAN-GNPDYADTFVFENDFPAVLLQVESVRGQCHVICFSPQHDKTLADMEIVPVIDAWNHVQIFENKGAIMGCSNPHPHGQVWSTEDIPQETAVELENMAKYMLCDYVKTETENASFICLVPFWATWPFETMVLS--RAHLARLSDMNSTQDLANILRRITCRYDNLFRCSFPYSMGVHQAPLHLHFYPPLLRSATVKKFLVGFELLGQSQRDLTPEQAAKRLA Mucci2 NNSHRRYNPLTKSWVLCSPHRTQRPWQGQQEPQYDPKCYLCPGNERAS-GNPKYDSTFRFPNDYAAVLIKVEGVRGECHVICFSPRHDLTLAEMDIKKVVDIWNHVQIFENKGAAMGCSNPHPHGQMWCTERIPEEPSKELIALEDYLLCDYAQREMENDTFLVVVPFWAVWPFEVMVLP--KTHIGSLPELDDKQDLADAVRRVTCRYDNLFKTSFPYSMGIHQKPLHLHYYPPLLRSATVRKFLVGFEMLGEPQRDLTPEQAAARLR Mydma EHTHQRLNPLLNEWVIVSPHRTKRPWNGQVELRHDITNPLCPGVMRPS-GNENYTSTYVFENDFPALLFQVKSATGICRVMCFHPYSDLSLPLMEILAVIAEWEWIQIFENKGTMMGCSNVHPHCQTWNT----NRERHYHMLQQSFHLA-------ENQDWLVVVPYWAMWPYELLVLP--KAPTKRISDLTQIQSLAIIMKIFLTKYDNLFKTSFPYTMGWHGAPLHAHYFPPLLRSASIKKHMVGFEMLAGPMRDITPEKAASILR Neucr2 DISHRRYNPLNGSWLLVSPHRTKRPWQGQQEPEYDPQCYLCPGNKRAQ-GNPHYKNTFAFVNDYSAVLLQAQPATGRCYVLTFSAKHDTTLADMEIVPVIETWRYMQIFENKGAAMGCSNPHPHCQIWTTSTLPEEPGKELAQMTKYLLEDYVKVEMQNDGFLVVCPWWAVWPFEVLVIA--KRHVRALVELTSEEQFAEAVQEVTRRYDNLFETNFPYSSGIHQAPFHMHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAAARLR Orpsp11 DHPHRRYNPLLDQWVLVSPQRAKRPWMGQKEPQHDKSCYLCPGNTRVN-GNPDYRGPYVFRNDFPALLFKINPERGINRVICFSDDHSLTLPIMDIEKVVTVWNHVQIFENKGSVMGCSNPHPHCQIWAQSSLPTQVAITQKNLKKYLLEDYLKKELENESFVVLVPFWATWPYETMIIS--KRHIKNILEFTGEELFAAILKEITIKYDNLFETSFPYSAGIHQAPFHMHFYPPLLRSATVKKFMVGYEMMGEAQRDITPEQSAAILR Pench1 DISHRRYNPLRGSSILVSPHRTKRPWQGAQEPNYDPKCYLCPGNERAQ-GNPHYESTFVFVNDYSAVFLKAEPVTGKCYVLTFSSAHNLTLADLEIVPVIDAWRYMQIFENKGAAMGCSNPHPHGQVWTTSSMPEEPAAEMDQLTKYLLEDYAALESENDAFLVVCPWWATWPFETMIVS--RTHKRALVDLSEADLLAEAIAEVTRRYDNLFETHFPYSMGIHQAPLHLHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAAAKLR Phybl2 HHSHRRYNPLTRSWVLCSPHRTQRPWQGQQEPSHDPKCYLCPNNQRAN-GNPDYTSTYIFPNDFAAVLLQVEGVRGECHVMCFSPRHDLTMAEMEIHSVVNAWSHVQIFENKGAAMGCSNPHPHGQMWCTDRIPEEPQTELNSLKAYMLCNYASRELENDSYVCVVPFWAVWPFETLVLP--KVHVSSLPQMTDEQDLADILRRMTCRYDNLFECSFPYSMGIHQAPLHIHFYPPLLRSATVRKFLVGFELLGEPQRDLTPEQAAARLR Picst3 NHSHRRFNPLSNTYVLCSPHRAKRPWQGAREPNYDPKCYLCPGNVRAT-GNPKFEATFVFPNDYPAVLLKTQGVKGKCFVICFSPNHSLTLPVMEITNVVEAWKYLQIFENKGFAMGCSNPHPHGQAWCLDVVPTEVDNELQNMQKYMLGDYVKLELENDSFIVVVPYWALWPFETLLIA--KEHLRSTQDFTEKHDLAEVLKVLTTKYDNLFNTSFPYSMGIHQAPFHMHFYPPLLRSATVKKFCVGFEMLGEPQRDLTSEQAAARLQ Plicr1 THSHRRYNPLTNEHVLVSPHRMKRPWLGQTEPEYDPACYLCPGNTRSG-GNDAYEHTMLFENDFAAILLATEPVQGGCDVLIFHPRHDLTLARLAIERIIEEWKYVQIFENKGSIMGCSNPHPHGQVWSLSAIPTIPATELASLKRYMLCEYVHFELKNAHWVALVPWWATWPFEILLLPH-GRHIPSIDRLTADESFADILAKVTKRYDNLFSCSFAYSMGVHQRPLHLHFSPPLLRSASVRKFLVGFELMAEAQRDLTAEQAALRLR Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 QHPHRRFNPLTHEWVICSPHRNNRPWQGQIEPPYDPNCYLCPNNTRAS-GTEKYTSTYFFENDFAAVLHRTEPARGKCYVICYNPRHDLTMAELEILPIIKAWKYIQIFENKGAMMGCSNPHPHGQVWALSYIPTIPTTVLKSQEDFLLLSYAHSELRTEFFLAVVPFWATWPFEVLVLPH-SHHMASLLDLPPGADLAMILSHVTRAYNNLFRCSFPYSMAIFQAPLHISFCPPLLRSATIRKFLVGFEMFGEAQRDLTPELAAEKLR Punst1 THPHRRFNPLTNEHVLVSPHRTKRPWQGQTEPDYDPNCYLCPGNSRAG-GNETYTSTTVFENDFAAVLLSTEPVSGGCDVLIFHPRHDLTLARLDILLIIEEWEYVQIFENKGAMMGCSNPHPHGQVWSLSAIPTLPAMELANLKKYLLCDYANFEVKNEHWVALVPWWATWPFEVLVLPY-RRHVPSLLHLTAEESFAQIISRLTKRYDNLFQCSFAYSMGIHQRPLHLHFSPPLLRSASVRKFLVGFEMMGEPQRDLTPEQAAARLR Rhior3 NNSHRRYNPLTKSWVLCSPHRTQRPWQGQQEPQYDPKCYLCPGNKRAN-GNPSYDSTFRFPNDFAAVLIKVEGVRGECHVICFSPRHDLTLAEMEVKKVVDIWQHVQIFENKGAAMGCSNPHPHGQMWCTESVPEEPQKELVALAEYLLCEYAQREMENDTFLVVVPFWAVWPFEVMVLP--KVHIGSLPEMNEKQDLADAVRRITCRYDNLFKTSFPYSMGIHQKPLHLHYYPPLLRSATVRKFLVGFEMLGEPQRDLTPEQAAARLR Rhoto1 DHSHRRWNPLKREWVLCSPHRTKRPWQGAVEPEYDDKCYLCPGNERAG-GTERYEGTFVFENDFAALLFQTQPARGKCYVICFSPRHDLTVAEMGVQRVIETWKYIQIFENKGSMMGCSNPHPHGQAWSLSYVPTMPERILASQRSWLLLTYAHSELLGDHFVALVPYWAAWPFEVLVVPY-KRHVPSLAYLEEEEDLARTLTSVGRRYDNLFECSFAYSMGIYQTPLHIGFYPPLLRSSTVKKYLVGFELFAETQRDITPEQAAVRLR Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 SHSHRRYNPLTDSWILVSPHRAKRPWLGQQEPLYDPKCYLCPGNKRAT-GNPRYESTYIFPNDYAAVLLKVQSVRGNCFVICFSPNHNLTIPQMDLVHIVNSWKYVQIFENKGTAMGCSNLHPHGQAWCLESIPSEVSQELKSFDKYLFADYVKLESENESFIVVVPYWAIWPFETLVIS--KKKLASISQFNQMVDLASILKQLTIKYDNLFETSFPYSMGIHQAPFHMHFYPPLLRSATVRKFLVGFELLGEPQRDLTSEQAAEKLR Salro DHSHRRYNPLLDEWVLVAPHRMKRPWKGQVEPRHDPKNGLCPNTTRAS-GTPDYTSTYVFVNDFPTFLMRLEGVTGECRVMCFHPFSDLTLPLMNIRKVVDAWKWVQIFENKGQAMGCSNPHPHCQIWASGHLPNVAARKNKHQLEYMLLDYAQLEAENDDWLVVVPWWAVWPYETMILPR-RRHILRLCDLTDTESLSSAMKTLLTKYDNLFQTSFPYSMGWHGAPLHAIYYPPLLRSASVKKFMVGYEMHAESQRDLTAESAARRLR Schco3 FNPHRRYNPLTGEYVLVSPHRMKRPWKGQIEPQYDPECYLCPANSRSG-GNEDYKHTFIFENDFAAILLASEPVQGGCDVLIFHPRHDLTLARLDIERIIQEWKYVQIFENKGAMMGCSNPHPHGQTWAMSAIPTLPAKELDSLRKYLLCEYAHFEAKNDHWLAVVPWWATWPFEVMLLPY-KRHIPSLQELTTEESFADALSRVTKRYDNLFFCSFAYSMGIHQRPLHLHFAPPLLRNASIRKFLVGFELMAEAQRDLTPEQAAARLR Schpo1 EYSHRRYNPLTDSYVLCSPHRAKRPWQGAKEVKYDPTCYLCPGNIRAT-GNPKYETTYVFPNDYPAVMFKTEGVKGKCFVICFCPNHNLTLPLMAICNVVETWKYLQIFENKGSAMGCSNPHPHGQAWCLDVIPSVVAQEMCNMTKYLLGDYVKLEMENDSFIVVVPYWALWPFETLLIA--KEHLKSLEEFEEKQDLASALKMLTTKYDNLFNTSFPYSMGLHQAPFHMHFYPPLLRSATVKKFCVGFEMLGEPQRDLTSEQAAARLQ Sorma DISHRRYNPLNGSWLLVSPHRTKRPWQGQQEPEYDPQCYLCPGNKRAQ-GNPHYKNTFAFVNDYSAVLLQAQPATGRCYVLTFSDKHDTTLADMEIVPVIETWRYMQIFENKGAAMGCSNPHPHCQIWTTSTLPEEPGKELVQMTKYLLGDYVKVEMQNDAFLVVCPWWAVWPFEVLVIA--KRHVRALVELTAEEQFAEAVQEVTRRYDNLFETNFPYSSGIHQAPFHMHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAAARLR Sphar EHPHRRYNPLTQRWLLCSPHRTKRPWQGGKE-PYDPRNNLLPGAVRTS-GNLEYESTFAFTNDFSALLFIAEAVRGECRVLCFHPRHDLTIAEMEIQAIVTLWNYVQIFENKGAAMGCSNPHPHGQIWSGSFIPENSRVSLESQANYLLQDYVEQEVQNEYFVAVIPFWAAWPYEVMIMPAPGRHYKSLSDLDDAAGLADAMGRVTRRYDNLFECSFPYSMGIHQAPMHLLYYPCLLRSATVKKFMVGFEMLGEPQRDLTAEQAADKLN Spipu1 DYSHRRWNPLTDSWVMCSPHRSKRPWHGEQGPAYDPTCYLCPSNSRAG-GNPSYTSTFVFPNDFPAVLLKAEIVRGQCRVVCFSPRHDLTMAEMEILAVVKTWNYIQIFENKGSMMGCSNPHPHGQMWALGDIPQEPSRELSSMKKYLLCDYVALETENDSFVCLVPFWAVWPFETLVVS--KHHLGSLVDLNPVQDLADVMRRVACRYDNVFESSFPYSMGIHGAPLHLHFYPPLLRSATIKKFLVGFEMMAEPQRDLTPEQAAERLR Sporo1 NHSHRRWNPLRQEWVLCSPHRTKRPWQGATEPQYDEKCYLCPGNTRAG-GTEKYDGTYIFENDYAALLFRTEPARGKCYVICFSPRHDLTVAEMEIVGVINAWKYIQVFENKGSMMGCSNPHPHGQAWSLSYVPSIPTSMLKSQRQFLLLTYANTELLGEHFVAVVPYWASWPFEIMVLPY-RRHIPSIVYLEEEEDLARMLGAVGRRFDNLFECSFAYSMGVYQAPLHLGFYPPLLRSSTVKKYLVGFELFAETQRDITPEQAAQRLR Stehi1 THPHRRFNPLTNEHILVSPHRTKRPWLGQTEPQYDPACYLCPGNERAG-GNDVYDATMSFVNDYAAVLLTTEPVNGACDVIIFHPRHDLTLARLDILRIIDEWKYVQIFENKGSMMGCSNPHPHGQAWSLTEIPHIPSLELSSLTKYMLCEYAHFEVKNEDWVALVPWWATWPFEIMLLPY-KRHIPSLTHLSSSESFASILSAITKRYDNLFSCSFAYSMGIHQRPLHLHFFPPLLRSASVRKFLVGFELMAEAQRDLTPEQAAARLR Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 DISHRRYNPLTDSWLLVSPHRTKRPWQGQQEPEYDPKCYLCPGNSRAA-GNPNYEQTFAFVNDYSAVLLRAQGVKGVCYVLTFSPKHNVTLADMDILPTINHWRYMQIFENKGAAMGCSNPHPHCQAWTTSTMPEEPGKELVQMAKYLLADYIKLELQNDSFVVVCPWWAIWPFEVLVLP--KRHVRALVDLTADEQLAEAIQEVTRRYDNLFECHFPYSSGIHQAPFHMHFYPPLLRSATVKKFLVGFELMAEPQRDITPEQATIRLR Umbra1 QHSHRRYNPLTKSWVLCSPHRTQRPWQGAQEPEYDPKCYLCPGNTRAN-GNPAYKTTYAFPNDFPAVLLRVTGVRGQCHVICFSPAHNLTIAEMDILPVVKQWNHVQIFENKGSAMGCSNPHPHGQMWCTEDVPEEPAKEIKAMAEYLLCDYAKLETENDSFACVVPFWAVWPFETMVVS--KRHVTSVSKLDDVQDLANILRRIACRYDNLFQCSFPYSMGIHQAPLHIHFYPPLLRSATVKKFLVGFEMMGEPQRDLTPEQAAERLR Ustma22 EHPHRRYNPLTRSWVLCSPHRTKRPWQGQEEPAYDEKCYLCPGNTRAT-GNDDYTSTFFFENDYAALLLQSQPARGRCYVICFNPQHNLTLAQLHIVPIIRSWKYIQIFENKGSAMGCSNPHPHGQVWSLDYIPEEPSKELASLRDWMLLTLAKLELSNSHFVAIVPYWAVWPFEVLLLPA-QRQIRNILQMTEVESLARILAETTCKLDNVFKCSFPYSMGVHQQPFHIHFYPPLLRSASVRKFLVGFEMMAEPQRDLTAEQAAKRIR Walse1 ESPHRRYNPLTDSWILVSPHRTKRPWQGQVEPVYDPKCYLCPGNERSN-GNPKYDSTYYFVNDFSAVLIKTSPISGRCYVVCFHPNHNRTIAQMDVFNVVKIWKYIQIFENKGSAMGCSNPHPHGQIWSVSYIPEEPAKALEMQGKYMLLDYAAFELSNDDFVAVVPYWAVWPFETLVIPT-KKHIPSVAYLNETESLAAILREVACRYDNIFDTSFPYSMGLTQQPLHIHFYPPLLRSASVRKFLVGFELLGEPQRDLTAEGAAQRIR Zygro1 DHSHRRYNPLKGTWVLVSPHRAKRPWLGQKEPPYDPECYLCPGNSRAT-GNPQYDSTFIFVNDFSAVLFKTESVRGVCFVICFSPQHNLTIPQMEVVKIVEAWKYLQIFENKGTAMGCSNLHPHGQAWCLESVPTEVLEELKSIKNYLLGDCVELELENDSFIVIVPYWAVWPFETMVVS--KSKVASIDKFNEMQDLSSILLELTKKYDNLFQTSFPYSMGIHQAPFHMHFYPPLLRSATVRKFLVGFELLGEPQRDLTAEQAAQRLR [Cluster2736.fasta_al_trimmed; alignment length = 158] Allma1 MFALTNATAAREVVNPRRFRKAHKGRIP--LPIGGSTAGTTLVYGDYGIRLR-EGGRLTAKQLEAARRVIRRKIRIVKGEMWLRVFPDVPVTSKGNETRMGKGKGTLDH--YMCRVPVNRVVFEIKGLHWEVAKDALRQGGMKLPEIVQRAEAAPK-A Ashgo11 MLSVMV-----QYA-PRQQDKKHKGRVP--VRTGGSIKGNTLEFARYGMRLKTEGVRLTALQLTEADNSIMRTVRQLTNKLWRRLCTNVAVGVKGNETRMGKGKGGFDH--WMARVPTGKIIFEMDGLHEKVAREAFRKAGTKLPEFVKRSK-ENMYR Aspfu1 -MKMLAPT---WLT-PKERSKSPKGRPH--VPTGGSSRGTTVVWGDYGLRMKDHDRRLPAASLKLAEETIKRRLRGMN-TLYKRVSANIGVYTKGNEQRMGKGKGKFDY--WTARVAVSRIVFELKGLHEKIAREAFRLAGHKLPEFVKKSSSSSASP Aurde31 SF-LLNPAAPSQLA-PRKFVKRHRGVIP--IPTGGSTKGTTLAFGDYGIRIRSEGKRLTAKQLQSADDVLKRKLKPLKGRIWLRVFPDVPVCVKGNETRMGRGKGLFEY--WATRVNTNRVLFEIGGIREELAREALRQAAAKLPEFITRSLSEAAAA Batde5 ------------LR-PKKYRKAHKGFFK--TRLGGSIRGTTVRLGEYGLQLF-EPGRLKDKQLDTVRTMVNRILKSEKGKLILRIFPHRPVTAKGAETRMGKGKGAVEY--YATWVSEGVVIMEITGARKDVALKALNVAAQALPRVV---------- Botbo1 LLQSIR-----QLA-PRKYRKAHKGRVP--IATGGSVKGTTLAYGDFGLRISGDGVRLTAKQLQSAEVALKRKLKVIKGVVWMRVFPDIPVCVKGNETRMGKGKGSFEY--WACRARTGRVVFELGGLREELAREALKLAAAKLPDFITRSPAAPLP- Botci1 -----------------EKKRSRKGRPR--VPTGGSARGTTLVWGEYGLRMCDHHRRVSAQQLKVGEDAIKVRLKGMR-RLYKRVAAQIGVYSSGNEVRQGKGKGSFDH--WASRIAVSKIIFELKGVHEQVARDAFRLAGNKMPEFVKKTSTSPDA- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MF---------EYA-PREVEKAQKGRVS--VRTGGSIKGNSLEFGKIGLRLKSQGIRMHANQLQAADKVLRRELRP-TKKLYTRFVCDLAVCIKGNQTRMGKGKGAFDH--WASRMPTGKVLFEIDGIHDKVARDALRKAADKLPEIITPYHTDPMYK Cangl MLRTVS-----EYA-PREQQKKQKGRVP--VRTGGSVKGSTLQFGQYGIRLKSEGVRLTAEQLKEADNAIMRYVRPLNNQLWRRLCTNIAVCIKGNETRMGKGKGAFDH--WMVRVPTGKILFEMAGLHERVAREAFRKAGTKLPEFVSRSQ-EPEYK Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 MLSLARPTAG-EIVHPRRFRKAHKGRVP--LPIGGSISGTTLQHGDYALVVR-EGGRLSAAQLEAARRIIRRKIRPVKGEMWLRVFPDIPVTSKGNETRMGKGKGTLEY--YMCRVPMNRVVFEIGGLRWEVAKDALRQAGMRLPTIVTKTAAVPKAA Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LLSQFKPTLLQYLA-PKESRKSRKGRCH--VPTGGSMRGTTVVWGDYGLRMRDHDRRISAHQLRIAEETIKKRLRGMK-RLYMRVAANIGVYTSGNDVRMGKGKGSFDR--WTARVAVSKIIFEIKGLHEQVVKDAFRLAGNKLPEFVKKVNTSPRAA Coere1 ------PTAATNLQ-PRKYKKAQKGRVP--VRVGGSTKGNYILSGDYGLRVK-EGLRLSAKTIEAIHAMLRRQLKAIKEQIWLRVFPDIPVSTKGNEVRMGKGKGAFDY--WACRVPKDKIIFELKGLNKELAKDALRQAGFKLGEIVIA-------- Conco1 FKNLARTTLTRNLA-PAKYRKAQKGRVP--VRTGGSQKGNTIAFGDYGIRLK-DGARLSASILTACNNIMKKKLKSAKGKIWMRVFPDIPVTSKGNESRMGKGKGAFDY--WACRVPKDKILFELGGLPLELAREAVRLASYYLPQFVVK-------- Conpu1 MF-SLAPSGIKQLA-PKLYAKRHKGRVP--VPIGGSIKGTTLAYGEWGIRIKGHGVRLTAKQLSTAQDVIKRKIKAIKGKCFMRVFPDIPVCIKGSETRMGKGKGTFEY--WATWVPTGRVIFEVGGIREEIAREALRQASDKLPEFIARTPQPA--- Copci MF-SLSATGHRQLA-PKKHLKRHKGKVP--IPIGGSTKGTTLAYGDWGIRIKDNGTRLSAKQLTTAREVIQKKLKVLKGKVYLRVFPDIPVCIKGSETRMGKGKGTFEY--WACRAPTGRVIFEIGGIREELARDILRQAAAKLPEFISREASSSAAA Croqu1 SLSTFR-----DLA-PRKYRKAFKGRPP--IRIGGSTVATTLEHGDFGLRVL-EPCRLSAKTLQSCETAIKKAIKSAKGKCYLRVFPDLPVCVKGNETRMGKGKGPFEY--WACRVPVGRVLFEVGGIQKELAFAALQHAKPRLPEFIDRSPTAVIER CryneH991 MINL--TSSPRQLA-PRKYRKAAKGAPGTQIPTGGSLKGTALHHGTFGLRAC-SSVRISAAQLTSCQAAVRRKIKPIKGQFYLRVFPDIPVCVKGNEQRMGKGKGSFEY--WSCRVKPGKVIMEVGGIREEIAKAALKLAQARLPEFITLAKEEGGAR Crypa2 ILSALQP----WLE-PFRTKKMQKGRPR--VATGGSVKGTTIMIGDYGLRMVDHHRRISAAQLKLAETTIKQRLRGQR-RLYTRVNCNIGVYVSGNEMRMGKGKGSFDH--WATRVAVNRVIFEIRGLHEQVVRDAFRLAGNKLPEFIKKPPS----- Debha1 MLGLGR-----EYA-PRRIRKAFKGRVS--VKTGGSIKGNSLEFGEYGLRLKSNGIRMTATQLQEADKVIKREIRP-SNQLITRFVCNTPVCIKGNQTRMGKGKGAFSH--WACRVTTGKVLFEIKGVHEKVAKEALRKASDKLPEIIKQAK-DSMFQ Dekbr2 MLARLS-----ELA-PRIQKKKQKGRVT--VRTGESEKGNTLTFGDYGMRLKSQGLRIKADQLQAADTILLKFVKA-GNKLWRRLCTNIAVCVKGNTTRMGKGKGPFDH--WAARVPTGKVVFEIA-MHEQEAKDALRRACDKLPEFIRTSR-QPEFR Dicdi ------------MKIPNKFTKNHKRNLI-------ETRKTGLVLGNYGIKAT-ETGYLKMKQMERIKGDLVKKLK----DIYFNFYPLFGLTNKGT-ARMGAGKGEVSE--WYVLVKKGSIVVE---IKSRMMQKVIRYSANKWPRMTQI-------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba MLSAVRPSTPALMM-PRKFRKRFKGRVYGR-----ASRGHYVAFGKYGLQVQ-HPVRLTAAQIESARRAITRRLKRV--RMWIRIFPDIQVSKKPAEVRMGSGKGSVDH--WVVRLKANRVIFEL--VPEPLARAAFRLAASKLPKFVLNAA------ Fomme1 MF-SLSAAPSRQLS-PRKWVKRQKGIIP--IPIGGSTKGTTLAFGEWGIRIKGNGARLTGKQLETVQELIKRKLKVIKGKVFLRVFPDIPVCIKGNETRMGKGKGTFEF--WATRVPTGRVIFEIGGIREELARDTLRQASNKLPEFITRTSAEPVTL Fusgr1 LLNAFQP--LRWLE-PNRKKKMAKGRPR--VATGGSTKGTTVLFGEYGLRMTDHHRRISAKQLKMAEDTIKVRLRGQK-RLYKRKNCNVGVYVSGNDMRMGKGKGSFDH--WATRMAVSQILFEIRGLHEQVVRDAFRLAGNKLPEFVKRSEASRNP- Galma1 MF-SLSASHPQQLA-PKKHLKRHKGRIP--IPVGGSTKGTTLAYGDWGIRIKGNGARLSAKQLTTAQEVILKKLKIIKGQVYLRVFPDIPVCIKGNETRMGKGKGTFEF--WATRVPTGRVIFEIGGIREELARDVLRLAAAKLPEFINRDQA---AA Ganpr1 --HALRPLAPLPFV-PRNHRKAQKGRLP--HSLGGSTRGSEVAWGTYGLRVL-RSVRMTARQLDATRNIIRRLLKPVKGRIYMRVFPDLPVTSKGAETRMGKGKGNVEF--WACRVRAGKVIFEIAGLSEDLAREALTAAMVALPEVV-LTPSSPSSS Gloin1 -----------EFA-PRKYRKAHKGRVP--VRIGGSTKGNTIAFGSFGLRVK-DGVRLSSAQLTAAHTVIKRKIKVIKGQVWMRVFPDIPVTSKGNETRMGKGKGSFEY--YACRVPMNKILFEIGGIRKEVAKEALRLASDRLPEFVDK-------- Hisca1 -LNIFQST---WLV-PKEKRKSQKGRPR--MPTGGSSRGTTVIWGDYGLRMKDHDRRVSADQLKIGYETIQKRLRGMK-KFYPRVAANIGVYTSGNEQRMGKGKGKFDY--WAARVAVNRIIFELKGLHEKVAREAFRLAAAKMPEFVKKEGSAPSQ- Klula1 MFSSV------EYA-PRNQTKKQKGRVP--VRTGGSTKGNSLQFGQFGLRLKSEGVRLTALQLKEADNAIMRYVRPLNNQLWRRLCTNIAVCIKGNETRMGKGKGGFDH--WMVRVPTGKVIFEMAGLHEKVAREAFRKAATKLPEFISKSQ-QPEYR Lacbi2 MF-SLSASAQRQLA-PKQHIKRHKGRIP--IPIGGSTKGTTLAYGEWGIRIKGNGARLSAKQLTTAQEVIMKKLRVMKGKVYLRVFPDIPVCIKGNETRMGKGKGTFEF--WATRVPTGRVIFEIGGIREELAREILRLASSKLPEFINRVQAAGNAA Lenti61 MF-SVPTSPLSQLA-PRKFLKRHKGVLP--IPVGGSTKGTTLAYGEWGIRVKGNGMRVTAKQLKSADDALRRKIKPIKGKVYMRVFPDIPVCIKGNETRMGKGKGSFEF--WATRVAPGRVLFELGGIREELAREALRLACDKLPEFIDRA------- Malgl1 SFRAFLLTAPMNLG-PRKYRKAQKGRVP--FPTGGSVKGTTVTQGVYGLRAL-DPSRITATQLTAAETALKRKLKVVRGQVFMRVFPDIPFCVKGNETRMGKGKGSFEY--WACRVPVGRVIFEIGGIRPEVAKD----------EFITSHELDPQLV Mellp23 -----------DLA-PRKYRKAFKGRLP--IRTGGSTVATTLEHGDFGLRAL-EPCRLSAKTLQSCETAIKKAIKSAKGKCYLRVFPDLPVCVKGNETRMGKGKGPFEF--WACRVPVGRVLFEVGGIQKELAFAALQHAKPRLPEFIDR-------- Mnele ML--LRPSDETLLR-PR------------------EFIVEPVQTARYGIVAL-ETGALGFKAVKASKEFITTNIERGK-RLFVRYFPDYPISLRPSNTRRGGGKNKVAE--YRDYVMAGRVLFEF--CSPVVATIIYDGVFKRMPMLVEGHKSFGNDR Monbr ML---------NKR-PKKYSKYQKGRINSNLPVNKQKNLENKDF-RYLLIAM-EPLRLTASHIAAGELAIKRELNIKFKDYNLHVFPHLPVTKKPAEVRMGKGKGSIDY--WMTRIRIGSPIFELKFIQIRCAKQIFDVVNSKLGK------------ Morel2 MASLFRLSAARSLQ-PKKYRKKHKGKIP--IPIGGSTKGTYVEFGEYGLRIK-EGARLTAKQIQAAHTTIRRKIKTVKGQIWTRVFPDIPVTSKGGESRMGKGKGSVDY--YATRVGLNRIIFEIGGIRREHAKEALRLASTKLPEFVVKTPIAPAVV Mucci2 MFSAFRNTTS-NFS-PKKYRKAHKGKIP--IPIGGSTKGTTVEFGDYGLRVK-EGARLTGRQLTAVHNALKRKIKPVKGQLWMRVFPDIPVSSKGNEVRMGKGKGTFEY--WACRVPLNRIIFEISGMRKEIAKEAFRLASHKLPEMVERSPSTPSST Mydma MF---------NLK-PR------------------FIHCDYVDSMDYGIYAL-TTGYIKESAMEAARVAIIRKTK----RQVNKIVSESPFTKKPLGTRMGKGKGKLDY--WASSAVAGQWLFEF--CDNELAKEAFNQVSKKLPHLRKR-------- Neucr2 LLSAFQP--FRWLE-PNRKKKMMKGRPR--VPTGGSTKGTTVVWGDYGLRMRDHHRRISAQQLKLAEDTIKQRLRGQK-RLYKRVACNVGVYVSGNEMRMGKGKGSFDH--WATRVAVNQIIFEIRGLHEQVIRDAFRLAGHKLPEFVKKPPS----- Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -IKMFAPT---WLT-PKEKSKSPKGRPH--VATGGSTRGTTVVWGDFGLRMKDHDRRMPASALKIAEETIKRRLRGMN-KLYKRVSANIGVYTKGNEQRMGKGKGKFDY--WTVRLPVSRIVFELKGVHEKVAREAFRLAGHKLPEFVNKSSSSDPTQ Phybl2 -----------DFS-PRKYRKAHKGKIP--LPTGGSTKGTSVEFGEYGLRIT-EGARLTSRQLTAVHNAIRRKIKTVKGQMWMRVFPDIPVTSKGNEVRMGKGKGTFEY--WACRVPLNRIIFEIGGLRKEIAKEAFRLASHKLPEMVER-------- Picst3 -----------EYA-PRAIRKTMKGRVS--VRIGGSIKGNSLEFGKLGLRLKSKGIRMAANQLLAADKVLKRELRP-TKDLITRFTCNTAVCVKGNQTRMGKGKGPFDH--WACRVPTGKVLFEIRGIHDKVARDALRKAADKLPEIITPGKTDPMYK Plicr1 MFPAFRPQASHALA-PKIHIRRHKGRIP--IPIGGSTKGTTLAYGDWGIRIKGNGVRFSAKQLTAAEEVIKRKIKAVKGKVFMRVFPDVPVCIKGNETRMGKGKGTFEF--WATRVPTGRVIFEIGGIREELARDALRLACDKLPEFITRTSSEAVA- Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 MLFNFR-----DLA-PKRYRKAFKGSTP--IRTGGSTVATTLEHGQFGLRVL-EPCRLSAKTLQSCETAIKRAIKPTKGQCYLRVFPDLPVCVKGNETRMGKGKGPFEY--WACRAPVGRVLFEVGGIQKEMAFAALQHAKPRLPEFIHLSPTAIISK Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 MFSISRSHTS-NFS-PKKYKKSQKGKIP--IPIGGSTKGTTVEFGDYGLRLK-EGARLTSRQLTAVHNTLRRKIKPIKGQLWMRVFPDIPVTSKGNEVRMGKGKGTFEY--WACRVPLNRIIFEIGGMRKEIAKEAFRLVSHKLPEMVER-------- Rhoto1 LFNGARASSSSLM--PRKHRKAAKGRVP--LALGGSIKGTVLEHGDYGLRAN-QATRLTAKHLEVCEATLKKALKPIRGQIWLRLFPDIPVCIKGNETRMGKGKGTFEY--WGTRARMGKVILEIGGLRPEMAKTVLRLASAKLPEFIDRAAAAPVEA Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 MFPYLT-----EYA-PRIVQKKQKGRVP--VRTGGSIKGSTLQFGKYGLRLKSEGIRISAQQLKEADNAIMRYVRPLNNHLWRRLCTNVAVCIKGNETRMGKGKGGFDH--WMVRVPTGKILFEINGLHEKVAREAFRKAGTKLPEFVSLSQ-EPQYK Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MLGLLRPTVSTQLA-PKKWDRKHKGRIP--IPTGGSTRGTTLAFGDWGIRIIGCGARLTAKQLGTAEEVIKRKLKILKGKVWMRVFPDIPVCVK---VRGGCSRGGVRVLTYMTGVPVGRVIFEIGGIREDLAREILRQASSKLPEFINKSTGDAAPQ Schpo1 QYNKFPPTRLNQYA-PRRNQKAQKGRVP--IPIGGSLRGTQLEWGEYGMRLKDRSIRFHAKQLETAEQILKRILKPIKARVYTRFCCNVPVCVKGNETRMGKGKGAFEY--WAARIPIGRVLFEIGGMRKELAEHALKQAAFHLPEIIVKSTTTAV-- Sorma LLSAFQP--FRWLE-PNRKKKMMKGRPR--VPTGGSTKGTTVIWGDYGLRMRDHHRRISAAQLKLAEDTIKQRLRGQK-RLYKRVACNVGVYVSGNEMRMGKGKGSFDH--WATRVAVNQIVFEIKGLHEQVIRDAFRLAGVKLPEFVKKPPS----- Sphar ------------MK-PKKHKKAFKGRVSSK-PIQ-----SDVDFGEYGLRAL-EPSRITAAQIYACKEVMLRRLR----QLWTRIFPDIPVSEKPAEVRMGKGKGSVEY--WCARVRPNTIIFEV--IPVEAAQDALQQASFKLGKFEIK-------- Spipu1 ILSSLRPQAP-NFR-PRKYKKSHKGFYP--THTGGSLRGTTVYYGEYGLQAL-EGGRLSDVQLDSARTGMRRVLKGEKGKFFLRCFPDRPVTSKGAETRMGKGKGAVDY--FATWVAEGRVVLEVKGVRKEVADKALRVAAAALPRVVGV-------- Sporo1 ------SSSARLV--PRKYRKAHKGRTP--LALGGSTKGTTLEWGDYGLRVN-EAVRLSAKHLETAEAALKRGLKPIRGKVYLRIFPDIPVCIKGNETRMGKGKGTFEF--WACRAKMGRVILEIGGLRPEMAHAVMRLAAAKLPEVIGR----PVAE Stehi1 MF-SFLQAARRDLA-PKRYLRRHKGVIP--INIGGSIKGTTLAFGEWGIRIKGLGVRLSAKQLSTAQDVLLRKMKVIKGKVYLRVFPDVPVAIKGNETRMGKGKGTFEY--WATRVPTGRVIFEVGGIREELAREALRQAASKLPEFISRPGSQS--- Tapde11 MFRSTC-----HQYQPKVYRKAHKGKVP--IPSGGSTKGTTIQIGDYGLRLKGEGKRLSAKQLQTCEAVIRRVIKVEKGRAFLRPACNIAVCRKGNETRMGKGKGEFDH--WAVRVPVGRIVWEIGG-SEELAREAFRQAGNKLPEFVKK-------- Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ------TSS--QLA-PKKYKKAQKGLPG-----GGSLKGTTLEHGSFGIRIL-ASTRITAAQLGAAQAALKRKIKPVKGEVYLRVFPDTPVCVKGNETRMGKGKGTFEY--WACRVPVGRVIFEIGGIREEIARQALKLAQVKLPEFINLAKDRGGAR Trire2 LLSAFQP--LRWLE-PSRKKKMAKGRPR--VATGGSTKGTTVIWGDYGLRMVDHHRRISAKSLKMAEDTIKVRLRGEK-RLYKRKCCNVGVYVSGNEMRMGKGKGSFDH--WATRMAVSQVLFEIKGIHEQIVRDAFRLAGNKLPEFVKKSAPSASS- Umbra1 FFSTLRSCLSRNLA-PRKYRKAQKGKVP--LPTGGSTKGTTVEFGDYGLRVK-EGTRLSAKQITAAYDTIRRKIKPVKGQLWMRVFPDIPVSSKGNEVRMGKGKGSNDY--WACRVPLNRVVFEIAGMRKEIAKEALRLASDKLPEFIERKPVIPEVQ Ustma22 MLSSLTASASRNLA-PRKYRKAHKITIP--FNTGGSTKGTTVQEGAYGIRLL-APARLSAKQLVAAETALKRKLKVVKGQVFLRVFPDIPVCIKGNETRMGKGKGTFEY--WACRANMGKVIFEIGGIRPEVAKEALRLASAKLPEFVTTAAAAP--- Walse1 ---MLN----RQLA-PRKYRKSHKGRVG--CPTGGSTAGTTLAFGEYGLRVK-QGARLSAKTLQSCEESIKRKIKPLKGQCFMRVFPDIPVCVKGNETRMGKGKGTFEF--WACRATPNKIIFEVGGMRAEVAQEALRLAQAKLPEFVRLGPAGPGIA Zygro1 MFSGL------EYA-PREQHKKQKGRVP--VRTGGSTKGSTLKFGTYGLRLKSEGVRLTAQQLKEADNALMRYVRPLTNQLFRRLCTNIAVCIKGNETRMGKGKGAFDH--WMVRVPTGKIIFEMKGLHERVAREAFRKAGSKLPEFVAPSK-EPQYR [Cluster2743.fasta_al_trimmed; alignment length = 159] Allma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 LMRYLRMENLEALLGVRILRQEPWETLCSFICSSNNNIGRITKMCHALCSQYGYYSFPTSEDALRDLGFGYRAKYIMAAAEWMDSEIRQRFM-EVPGVGPKVADCVCLM-GMQMDDHVPVDVHINRIAQRDYIAALKARYQKWGPYAGWAQGVLFAQEI Aspfu1 LKHYLNLSNLTDLYGIRILRQDAWEALVSFICSSNNNITRISQMVEKLCVNYGYHDFPPVEGRLRSLGFGYRAKYIHQTALIVAKHAHEQLL-GLQGVGPKVADCVCLM-GLGWGEAVPVDTHVWQIAQRDYKSLTKATYKLWGKEAGWAHSVLFTADL Aurde31 MRDYFQLDDLSDLYGLRMLRQDPWENLISFICSQNNHISRISKMVQALCTHFGYHSFPPVAAKLRALGFGYRAEYIQRTAQMVLEAARAELL-KLMGVGRKVADCILLM-SLDKREVVPVDTHVYQIALKHYPAMTPKIYDLWGDYAGWAHSVLFTADL Batde5 LYDYFQLGSLELLYGLRVLRQDPSENVFSFICSSNNNIPRISSMIRSLCAEYGFYTFPEVEQRLRQLGFGYRAKFIVGSAKLILEAAHTELL-SLPGVGPKVSDCICLM-SLDKIGAIPVDTHVWQIAQRDYKTITKSLYEVFGEYAGWAHTVLFCADL Botbo1 IRDYFQLDDLERLYGIRILRQDPWENLVSFICSTNNHISRITSMVENLCIHFTYHPFPTTEATLRNLGFGYRAKYIQKTAALLCEAARLELL-KLHGIGPKVADCILLM-SLNQPAVVPVDTHVYQIAVKHYSSMTPKMYSVWGSYAGWAHCVLFTADL Botci1 LRHYLNLSNLTEMYGVRILKQDAWEALVGFICSSNNNIIRISQMVNNLCLHYGFHDFPQVESHLRALGFGYRAKYIAQTASIAASH--------------------------------PL--------------------------------------- Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 INDYFVLDKLTDLYGIRILRQDPWECLISFICSSNNNVKRISKMCENLCINFGYYTFPTVEAKLRDLGFGYRAKYIYQTACKFTDTAHEFLL-QLTGVGPKVADCICLM-SLDKHDVVPIDTHVYQIAVRDYKTLNKETYDIFGEYAGWAQSVLFAADL Cangl LKNYFRLDDLQNLHGIRILGQEPWETLVSFICSTNNNIGRISKMCHALSENFGYYTFPSTEIQLRGLGFGYRAKYIIETAKKFVEEAREFLM-GYCGVGPKVADCVCLM-GLHMDEVVPVDVHVGRIAKRDYLQELRGQFEIWGEYAGWAQGLLFFRET Capow LRRYFWLDKLEPLYGVRILRQDPTENLFSFICSSNNNISRITLMIDRMCQQYGFFDFPEVEERLRELGFGYRAKFIEQAAKQVLKTARTNLV-QLQGVGPKVADCICLM-SMDKHDAIPVDVHVRRLAERDYKTMTAAAHKLWGEYAGWAHSVMFSGEL Catan2 LHDYFQLSSLPALYGIRLLRQPPVETLFAFICSANNNIARITGMVQALAMRYGMYVFPSIEGVLRGLGFGYRAKYIAATVKTLGGEVRDALV-QLQGVGRKVADCVALM-SLDQPGAIPVDTHVWQIATRDYKSLTPTTYTLFGPEAGWAHSVRLTREH Cioin LCDYLRLNDLKKLYGIRVLRQNPLETLFCFLCSVNNNITRIVSMIERMCKLYGFHDFPTTDEDLRKLGFGYRAPFIGKCAKEVMSKAFTALT-DLTGVGMKVADCVCLM-AMDKLEAVPLDTHVRQVALRDYKTLSTRSYSLWGGYAGWAQAVIFVNEI CocheC53 VNHYFNLSNLGHLYGIRILRQDAWEALIGFICSSNNNISRISGMVHNLCLHYGYHDFPTVEAHLMKLGFGYRAKYIAKTARIVSEKAHEELL-ALHGVGPKVADCVCLF-GLGWSESVPVDTHVWQIAQRDYSSLTAATYKLWGKEAGWAHSVLFTADL Coere1 LHDYFQLHKFDSLCGVRTLRQPVVETLFTFIASSNNNIKRITMLVDKLCEHYGFFTFPTIELTLKQLGFGYRAKYYANSIKILCQSARNELL-RLSGVGPKVADCVCLM-ALDKYDAVPIDTHIWQVAQRRYKTPTTKTYHLFSPYAGWAQGLLFSGDL Conco1 LEDFFQLNNLQVEYGLRMLRQDPLENCFSFICSSNNNVKRITKMLNSLCQIYGFYTFPDVEKKLRELGFGYRAKYINQAAKLIHAEVHNALI-EIPGVGPKVADCICLM-SMDKHEAIPIDTHIWQIATKDYKTLTKSNYNLWGPYAGWAHSVLFTYKM Conpu1 IRDYFQLDKLETLYGIRMLRQDPWENLVSFICSSNNNISRITKMVHSLCKKYSYHPFPPASATLRSMGFGYRADFIQKTAKLLVDEARVELL-KLMGVGRKVADCVLLM-SLDKREVVPVDTHVHQIAIKHYATLTPKLYNIWGEYAGWAHSVRFTGRR Copci LRDYFQLDDLESLYGIRILRQDPWENLVSFICSSNNNISRITKMVHNLCQHYSYHPFPPVSATLRSLGFGYRADYIQRTAKMLVDKAREELL-KFVGVGRKVADCILLM-SLDKKEVIPVDTHVHQIAVKHYTAMTPKLYSLWGDYAGWAHSVLFTADL Croqu1 LCDYFVLDSLRDLYGLRVCRQDTWETMISFICSANNNIPRITSMIYRLCETYGVYAFPTPER-LRSLGFGYRASYVSSTAKTLASAAHEALVKNFDGVGPKVADCICLF-GLGFVGVVPVDVHVFAIAKRDY---GKAGYEIWGPWAGWAQQVLFLADL CryneH991 LEDYFQLVDLETLYGVRVLRQDPWECLLAFITSTNNHIPRITSLLHKFSQSFTYHLFPALEKPLRDMGFGYRAPFIEASLQMLRNIVRENLI-ALKGVGRKVADCVMLM-CLDKPSLIPIDTHVAHIAARHPKAMSKQVYDRWGPMGGWCQAVLFAADL Crypa2 LKNYFNLHDLAGLYGVRILNQDAWEALVGFICSSNNNISRISQMVHKLCLNYGFHDFPTVESRLRELGFGYRAKYIAETARNISQHAHEQLL-ELCGVGPKVADCVCLM-GLGWGEAVPVDTHVWQIAMRDYKTLSKAMYNLWGSQAGWAHSVLFTADL Debha1 IKDYFNLPKLETLYGIRILRQEPWETLISFICSSNNNVKRISKMCDNICTEFGYYSFPTVESRLRDLGFGYRAKYIYQTALKFTSTAHDFLL-QLTGVGPKVADCICLM-ALDKHDIVPVDTHVYQIAIRDYKTMNKKTYEIFGDFAGWAQSVLFTSDL Dekbr2 LKEYLQLDNASSLYGIRILCQDPWENLICFICSSNNNVKRISQMCDTLCIHYGHYTFPTTEQKLRDLGFGYRAKFIYETA-KICVKCQEFLL-QFPGVGPKVADCVALM-SLKKHNVVPIDTHVYQIAKRDYKTMTKNVYHLWGDYAGWAHSILFAADL Dicdi LQNYFYLDDINQLFGLRLTRQNPVDCLFSFICSQNNNVSRITSLVNKLIVGYGYYKFPTVEE-LNDLGFGYRSKYIVESCKQVIEEVQKELT-TLMGVGKKVADCVSLM-SMDNPNAVAIDTHIYQISKK--SSLTPKLYSIFGDHAGWAQTILFANEL Dmel ISDYLRVDDLKVNQPVRLLSQEPFENIFSFLCSQNNNIKRISSMIEWFCATFGAYTFPTLNAQLRAAKFGYRAKFIAQTLQEIQKKAREELT-LLPGIGYKVADCICLM-SMGHLESVPVDIHIYRIAQNYYKNVTKKIYKLHGKYAGWAQAILFSADL Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 IQDYFQLDDLLKLYGIRMLRQDPWECLISFICSSNNNISRISKMVQNLCTHFSYHPFPPVSTKLRTLGFGYRADFIQKTASMLLKEAREELM-KLMGVGRKVADCILLM-SLDKREVIPVDTHVHQIALKHYTAMTPKLYKIWGNYAGWAHSILFTADL Fusgr1 LRHYFNLDGLESLYGVRILNQDAWETLIGFICSSNNNISRISQMVHKLCRHYGFHDFPSVEAHLRTLGFGYRAKYIAETARIVANEAHQQLL-TLKGVGPKVADCVCLM-GLGWGEAVPVDTHVWQIAQRDYKTLNKATYNLWGSYAGWAHSVLFTADL Galma1 LKDYFQLNDLVSLYGIRILRQDPWENLISFICSSNNNISRITKMVQGLCREYSYYPFPPVGLKLRALGFGYRADFIQKTAKMLVDDARQELL-KFVGVGRKVADCILLM-SMDKKEVIPVDTHVIQIATKHYTNMTPKLYSIWGEYAGWAHTVRI---- Ganpr1 LRDYFQLDSLQDLYGIRVLRQHPVENLITFICTSNNNVARITLMVNALCREYGFHDFPVLESRLRELGFGYRAKYITQTCARLSEDAIQALL-EFPGVGPKVADCVALM-SLDKREAVPVDRHVWQIALRDYYTLTPKVYSLHGEYCGWAHSVLFTADL Gloin1 LIDYFQLNSLSECYGIRILRQDPIENLFCFICSTNNNINRITQMVEKLCRQYGYFDFPTVEDELRKLGFGYRARYIVQTAKYICEEAHAALL-KLSGVGPKVADCVCLM-SLNKHNAIPVDTHVWQIAQRKYNSLTSRNYKIFGEYSGWAHSVLFTSDL Hisca1 INNYFNLDNLTDLYGIRILRQDSWEALISFICSSNNNIARISQMVEKLCLNYGYHDFPTVEARLRELGFGYRAKYIYQTALIVVNKAHECLL-ELQGVGPKVADCACLM-GLGWGEAVPVDTHVWQIAQRDYKSLTKATYSLWGKEAGWAHSVLFAADL Klula1 LKDYFELDSLNNLMGVRVLNQNPWETLCSFICSSNNNISRITKMCHSLATEFGQYSFPSSEEKLRDLGFGYRAKYIIGTAQLMSMDVKEKLM-AYPGVGPKVADCVLLMGGLGFDEVVPVDVHIARIASRDYISELQAEYDLWGPYAGWAQCVLFAQEI Lacbi2 LKDYFQLDDLEKLYGIRMLRQDPWENLLSFICSSNNNISRITNMVQNLCKHYSYYPFPPVRTTLRTLGFGYRAEFVQRTARMLFQDARQELL-QFIGVGRKVADCVLLM-SLDKKEVIPVDTHVHQIAIKYYINMTPKLYSIWGDYAGWAHSVLFTADL Lenti61 IRDYFQLDDLVDLYGIRMLRQDPFENLISFICSSNNNIARITKMVKSLCLTYSYHPFPSVTARLRTLGFGYRADFIQKTAAMLVDDARTELL-KLMGVGRKVADCILLM-SLDKREVIPVDTHVHQIAVKHYGTMSPKLYAVWGEYAGWAHSVLFTADL Malgl1 ---------------MRLAQPD-------------------------------------VESKLRSLGFGYRAKFLARTAQVLCEEARAKLM-ELPGIGPKVAE--------------------------------------------------FTQTC Mellp23 LNDYFVLNSLQKLYGLRVCKQDPWETLISFICSSNNNIPRITSMINNLSESFDIHTFPTETK-LKQLGFGYRSSYIMTSTQSLIEVAHQTLITHFSGVGPKVSDCICLF-GLGFKETVPVDVHLYQIAKRDYKTVSKQDYELWGDYAGWTQQIIFFIDL Mnele LSDYFNLKKLSDMAGLRLIRQDPYECLLTFITSSCNNIPRISSLMLKLSQ---FHALPDTERKLRSLGFGYRAKYLVSAMRAVEKEAREQLT-GLAGVGPKVASCVCLM-SLDKHDSVPIDTHIHQVAVKHYKSLTPALHTKHGQYAGWAQAYLFYSNS Monbr LRDYFQLDSLSRLYGLRVLRQPPFECLISFICSSNNNIGRITLMLDRLKQHYGLYSFPT-EAHLRELGLGYRAKFITETCQALQRQVQE--------IG-----------------AIPVDTHVWQIAVRDMRSLTPTIYARYGSYAGWAHSLLFAAEL Morel2 LRDYFQLDPLTELYGVRMLRQDPIENLFCFICSSNNNISRITQMAAKMCSEYGFYEFPTVEETLRNIGFGYRAKYIATTARMIQEDAHAALL-TLQGVGPKVADCVCLM-SLDKHETIPVDTHVWQIAVRDYKTISPAIYDLFGGYAGWAHSVLFAADL Mucci2 IRDYFQLDSLRDCYGIRMLRQDPWENLISFICSSNNNISRISQMVNKMCVRFGFYEFPTVESILRELGFGYRAKYIANTCAKIKAEAKSSLM-TLQGVGPKVADCVCLM-SLDQTESIPVDTHVWQIALRDYKTLDSKLYTLFGEYSGWAHSVLFTADL Mydma LYDYFQLDDISKLYGIRVLKQDPVENLFSFICSQNNNIVRISQLVEKLCVFFGVFCFPTVEDALRKLGFGYRAKFIHHAAKSIIEEAIQNLC-SLPGVGAKVADCVCLM-SLNKKNAIPVDTHMWQIASQYYKTLTSKVYELYGEYAGWAHSVLFTTDL Neucr2 LHNYFALSSLTTLYGIRILNQDAWETLISFICSSNNNISRISQMVLKLCTHYGFHDFPGVEAHLRELGFGYRAKYIAETAGCVAQKAHEALL-TLPGVGPKVSDCVCLM-GLGWGESVPIDTHVWQIAQRDYKTLNKAMYKIWGPQAGWAQSVLFTANL Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 IKHYFNLTNLTELYGIRILRQDAWEALVSFICSSNNNIARISQMVEKLCIHYGYHDFPPVESNLRKLGFGYRAKYIYQTAVMVSNEAHEKLL-ELQGVGPKVSDCVSLM-GLGWGESVPVDTHVWQIAQRDYKNLNKTTYKLWGKEAGWAHSVLFTADL Phybl2 LRDYFQLDSLSECYGIRILRQDPWENLVSFICSSNNNISRISQMVNKLCVQFGFYAFPPTQDQLRELGFGYRARYIAQTAAQIAAEAKTALM-RYPGVGPKVADCVCLM-SLDQHEAIPVDTHVWQIAMRDYKTLTPALYDLFGSYSGWAHSVLFTADL Picst3 VKDYFNLSNLVDLYGIRILRQDPWETVVSFICSSNNNVKRISKMCDSLCLEFGYHSFPSIETRLRELGFGYRAKYIYQTAVKFVDLSHNFLL-QLTGVGPKVADCICLM-ALDKHDCVPVDTHVFQIAVRDYKTMNKVTYDLFGEYAGWAQSVLFASDL Plicr1 IQDYFQLDDLLGLYGIRMLRQDPWENLVSFICSSNNNIARITKMVQSLCKQYSYHPFPPVTSVLRSLGFGYRADFIQRTAQMLVDVAREELL-KFVGVGRKVADCVLLM-SLDKREVIPVDTHVHQIAIKHYQNMTPALYGVWGDHAGWAHSVLFTADL Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LKAYFVLDSLVNLYGLRVVRQDSWETMISFICSANNNIPRISLMLNRLCATFGFFSFPSIDK-LKLLGFGYRASYVYKTSIKLCEQAHSKLVNQFPGVGPKVGDCICLF-GLGFVHVVPVDIHIYKIALRDYKKKKKKSLSTWGPWAGWAQQILFLADL Punst1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 -------------------------------------------MVHKLCVEFGYYDFPTVEKRLRELGFGYRAKYIANTAKKLNAEAKEELM-KFQGVGPKVADCVCLM-SLDHPESIPVDTHVWQIASRDYKTLTSIVY------------------- Rhoto1 LRTYFQLDDLDSLHGIRVLKQDEWETLVSFICSANNNIARITLMVNRLCAALGLFSFPPIDPLLRQLGFGYRAPFIPSTAQTLLSEAREKLV-AFKGVGRKVADCVLLF-GMGWNELVPVDTHVFQIAVRDYASLTPALHSKWGPYAGWAQQVLFFADL Rozal11 NQFYFFCHHIQSLIGNRVLRLEPFPTLISFICSSNNNVPRISSMVLNICKKYGFYTFPSLEEDLRILGFGYRAKYIHKTVQNLFNETIKKLL-SFSGVGPKVAECIALM-SLDKTMAVPVDTHIATV-----ASVSPKLHSLYGEYAGWAHSMLFTREL Sacce1 LMKYFRLDSLKHLFGIRILAQEPWETLISFICSSNNNISRITRMCNSLCSNFGYHSFPTTEAKLRELGFGYRAKYIIETARKLVNDVREHLM-SYNGVGPKVADCVCLM-GLHMDGIVPVDVHVSRIAKRDYLKELRTKYKKWGSYAGWAQGVLFSKEI Salro LSDYFQLSKLKPLYGLRVIRQPPFECLISFICSSNNNIARITSMLSSLRLRYGIHAFPT-EQELRDLGFGYRAKFIVKTVDALKAQV------------------------------------LWCIAVRDYKSLTPRVYQRFGDHAGWAHSVLFAAEL Schco3 LRDYFQLDDLVKLYGIRMLRQDPWENLVSFICSSNNNISRITKMVQNLCREYSYHPFPPVATRLRALGFGYRADFIHKTAKMLVDEAREELL-KFMGVGRKVADCVLLM-SLDKREVIPVDTHVHQIAAKHYVPMTPKIYGIWGEYAGWAHSVLFTSDL Schpo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma LHSYFALSSLTTLYGIRILNQDAWETLISFICSSNNNISRISQMVLKLCTHYGFHDFPGVEAHLRELGFGYRAKYIAETAGCVAQKAHEALL-TLPGVGPKVSDCVCLM-GLGWGESVPIDTHVWQIAQRDYKTLNKAMYKTWGPQAGWAQSVLFTANL Sphar -IQYASIR------GLRTMRQDPVENVFSFICSSNNNIARITQMVHNLKRVYG--------------------------------------I-SHEGLG------MCQP-EL----------------------------------------------- Spipu1 LRDYFQLDDLGELYGIRILRQDPVENLFTFICTSNNNIQRITTMVSKLCQHYGFYSFPTVENELRQLGFGYRAKYISQTARYIMEECRDELL-KLAGVGPKVADCVCLM-SMDKPGAIPVDTHVWQIAKRDYKTLTQKNYTIFGTHAGWAHSVLFTADL Sporo1 LVEYFQLSPLAPLYGIRVLKQDEWETLVSFICSANNNIARITLMVNRLCAQLGLYSFPPTEALLRQLGFGYRANFIPTSAIHLVEQVRDKLL-EFKGVGRKVADCVLLF-GLGWSQVVPVDTHVFQIAIRDYTALSPVLHKLWQPHAGWCQQVLFFADL Stehi1 INDYFQLDDLVKLYGIRMLRQDPWENLISFICSSNNNIARITKMVNALCSNYSFHPFPPVASELRKLGFGYRADFIQKTAKMLVDQARVELL-KLMGVGRKVADCILLM-SLDKREVVPVDTHVHQIAIKHYQNMTPKLYTVWGEYAGWAHSVLFTADL Tapde11 LKDYFNLSDLEALYGLRMLRQDPFENLLSFICSSNNNIARITQMVQNLCKHYGYYDFPRLDQELRALGFGYRAKFIAATARQLSEEAHAELM-KFMGVGAKVADCVCLM-SLDKHQAVPIDTHVMQIAQRDYSAMTKVLYELWGPYAGWAHSVLFTADL Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LEDYFQLVDLSLLYGVRVLRQDPWECLISFITSTNNHITRISSLMHKLSINYSYHPFPIFETNLRQLGFGYRASFIESSIKSLRQVIGECLI-SLKGVGRKVADCVMLM-SLDQPSLIPVDTHVASIAARHPKTMSKQMYDRWGPLGGWCQAVMFAADL Trire2 LRHYFNLNDLASLYGVRILNQDAWEALICFICSSNNNISRISQMAHKLCKYYGMHDFPTVEARLRELGFGYRAKYIAETARIIAQDAQTALL-SLTGVGPKVADCVCLM-GLGWGESVPVDTHVLQIAQRDYKTINKAMYSIWGKYAGWAHSVLFTADL Umbra1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 LTDYLSLDPLESLYGLRMLRQDPWECLCAFVCSSNNNIARIGQMVQNLCTHFSFHPFPPVEEKLRELGFGYRAKYLARTAQMLYAEARDQLI-QFPGIGPKVADCILLM-SLDQASSIPVDRHVFQFAEKWY-----KKYDLWGDYAGWAHSVLFTADL Walse1 IHDYFQLDRIIDLYGILILRQDPWECLISFICSSNNNIARISQMITKLSTTFSRYPFPPVEDTLRTLGFGYRAKYVANVAKMLVENVIPQLT-RMMGVGPKVADCVALM-SLDQHSSIPVDTHVWQIAVRDYSAMSPSIYDLWGPYAGWAHTVLFAADL Zygro1 LIRYFRLDPLQELHGMRMLGQEPWETLVSFICSSNNNISRITKMCSNLCIHYGFYSFPTSETQLRELGFGYRAKFIIETAKKMVQQMREHLM-SYQGIGPKVADCVCLM-GLRMDQVVPVDVHVGRIAKRDYLKKLSEKYELWGPRAGWAQGILFTNEV [Cluster2767.fasta_al_trimmed; alignment length = 97] Allma1 MPPQGGFA-RVQYKRNIPARGPSGAALFIVAYGW--YWNIQGIRERREIRREQTWARIHLVPMLQAEQDRHEARMLAQQEEIERKAMKDVKVYH-TD Ashgo11 ------------------------------------------------------------------------------------------------- Aspfu1 MPPSGGYA-PVQYKRNLPARGFRPIYYLFMAYGY--YKLFYGIREQHELAREKVWSRLHLVPLLQAEEDRDQVRRHFADKAREKELLGTEKVYN-SD Aurde31 MPPAGGFE-TIRYKRSLPVRGPGTYTVLLMLYGC--WRVSRARIEQTELAREKAWARIHLVPLLLAEADRDAFRRQQMQHAREAAIMRNVRGYN-EP Batde5 LSPPNGFPHTIKYKRYLPARGPSGAVMIIMSYGW--CMVLDANQENRELLREKAYARIFLAPLLQAETDRDLVRRLDCLKGREAGMMKDRPVYH-TK Botbo1 MPPAGGFE-AIRYKRNLPARGPGGAAILVCGYGF--YKLGLGNLEKRELKREKAWSRIHLVPLLLAEGDRDIYRREQAALAREKEIMKDVSVYN-NK Botci1 ------------------------------------------------------------------------------------------------- Caeel MPPKGGYR-AFNFHRTFPKLVWSPGTVVATAYGV--YAALEGKKKDITEKFEDVDINNAMEPFLTAERDRYWLKLLAKNRALEEEIMKDVPVYF-TL Canalb1 LPPIGGYE-PIQWKRNIPSRGFSGTVYFLMSFGF--YKYYKAADEQREFTRERNWARFHLEPLLIAEEDRNVARRYFAELKRRKESMSPEDIYN-DK Cangl ------------------------------------------------------------------------------------------------- Capow MPPQGGFA-DVPFRKPKAVRGLSGAALFTMFGGL--FIVGQGNKTRRYWREEQVIARRNLVPMLQAEEDRRFVLAKRAAEAKEAELMKNVKIYN-TD Catan2 MPPKGGFE-PLRYKRNLPARGPSGAVLFICAYGW--YWTIQGIRERRELRREQTWSRIHLVPLLQAEADRGEARLLQQQEEIERKAMAGVKIYH-TK Cioin MPPPGGYG-AVPYKRNLPVRGLGGFALFLSAIGV--KMLWERKVLEEFTNQESHQAELVYYPLLQAEKDRTELRLHKEKIESE-------NVYH-TP CocheC53 MPPQGGYS-PVQYKRNLPVRGFRPAAYILMTYGF--WRVGQGIREHNELAREKMWARIHLIPALQAEEDRDQVRRYLADRAREKELLGTEKVYN-SD Coere1 MPPSGGFK-PFRYERRLPKRGPSGVGMFIMAYGW--YRVYLGLDERRELEREKIWSRIYLTPMLIAEADRDEYRRRCAAVDREREIMKDIGVYH-GK Conco1 MPPRGGFP-TIRVDRNLPKSRLTGLGIFLSIYGF--HRVLEGKIERKEINREKVWARINLVPLLEAESDRDKYRRGQAALAREAEIMKGVSVYN-TD Conpu1 MPPPGGFE-SVKYKRNLPFRGPSGIVALVCAYGF--YRVGKGNLEKRELQREKVWSRIHLVPLLLAEGDRDAYRRQQAALAREKEIMKDVSVYN-NG Copci MPPPGGFQ-AVKYKRNLPTRGPGAYVILICVFGF--YRLGKGNLEKRELEREKIWSRIHLVPLLMAEGDRDTYRRQQAALAREREIMKDVSVYN-NP Croqu1 LPPAGGYE-PIKFKRNLPVKGPSGAVIFFCTYGF--YQYAQGNKELRELKRENLWSRIHLVPFLMAEADRDRYRREQANLEREKQIMEDVSVYN-SK CryneH991 MPPPGGYE-TLRYKRNLPLKGPSGAVLFICIAGF--YRLGQGNVEKRELKREKAWSRINLVPLLLAEQDRDAYRRQQAALAREKEIMKDYRTYN-SA Crypa2 MPPVGGYD-PVQYKRNLPARGFKPATLLVMLYGW--YKYGKGAREQRELAREKMWSRIHLIPVLQAEEDRDQVRRYLADQAREKELMGDNKPYH-SD Debha1 LPPIGGYE-PVQWKRNLPSRGFRPAIYFLMAFGF--YKYYKGVDEQRELARERQWARFHLEPLLLAEEDRNVARRYYSEKARQRETMSPEELYH-DK Dekbr2 LPPIKGYE-PIQWKRNLPSRGFRPSIWLLSSYGF--YKLIQGNRENIELSREKLWARINLIPLLQAEQDRDVVRRTLSYYNRERNTYSDKGIYN-GN Dicdi ------------------------------------------------------------------------------------------------- Dmel LPPPGGYK-KIPFARVPPKSYFTGFTTIVTAVGLGIYYLTAKKVKRDEI--EMRSAQNVIFPILVAERDREFLRQLRRNRDEEAELMKNVEFYAHSD Enthi ------------------------------------------------------------------------------------------------- Falba LPPPGGYSAPKQFSAHLPRRGLSSVTMLVMAFGF--YGVHVQRTRARITAAEDRNAKYCITPFLLAE-DRLATHSKQTLVRNYSLIANDATPYFDSE Fomme1 MPPPGGFE-SIKYKRNLPFRGPSSAAIVICAFGF--YRLGQGNLEKRELQREKTWSRLHLVPLLLAEGDRDAYRRSQAALAREKEIMKDVSVYN-ND Fusgr1 MPPKGGYE-PVQYKRNLPARGLRPGILLVMGYGW--YKLIGGMREMNELGREKMWARINLIPVLQAEEDRDQVRRYLADQKREKELLGDNKVYN-SN Galma1 MPPPGGFE-SVKYKRNLPLRGPGAYAILICAYGF--YRLGKGNLERRELEREKIWGRIHLVPLLTAEGDRDMYRRQQAALAREKEIMKDVSVYN-NP Ganpr1 LPPPGGFA-PVRFARNLPKKGPSGAFLFVSGWGF--MKIGELNAERRELRREKTWSRIHLVPILQAETDRDTVRRMDALASREAEIMQQVPVYH-TK Gloin1 LPRPGGFP-AVQYKRNIPRRGPSGLVLFISALGF--YWMTQTILESRELKREKSWSRIHLIPMLQAEFDRDTYRRSQASLKREAEIMKDVSVYN-SK Hisca1 MPPAGGYQ-PIQYKRNLPVRGFRPVYYLIMAYGF--YKVFLGIREQNELGREKMWSRIHLIPLLQAEEDRDQVRRHLADKAREKHLMGSENVYH-SD Klula1 ------------------------------------------------------------------------------------------------- Lacbi2 MPPTGGFE-SLKYKRNLPYKGPGAYVLLICAYGF--YRLGKGNLERRELQREKVWSRIHLVPLFLAEGDRDMYRRQQAAIAREKEIMKDVSVYN-SS Lenti61 MPPPGGFE-PVKYKRNLPLRGPSGLVILVCAYGF--YRVGKGNLEKRELQREKVWSRIHLVPLLLAEGDRDAYRRQQAALEREREIMKDVSVYN-NP Malgl1 -------------------------MLIISAFGF--WRLGLGNAERRELARERAWSRIYLAPLLLAEADRDAFRRDRAALLREKLLMKDVSVYN-TK Mellp23 LPPVGGYE-PIKFKRNLPVKGPSGAVLFLCSWGF--YRYAQGNKELKELKREDIWSRIHLVPFLTAESDRDRFRREQANLEREKQIMEDVSVYN-SK Mnele MPPKGGYA-PIHWKRYAPKRTIPGYFIFGSMYCY--FKMALMRFEHRVNDHHEFFIRKNLYPFIWAEEDRRMVRARKQHEEDLRRTFAQESRYSVND Monbr MPPAGGYT-SVPYKRNVPYRGPHGAVLFVMAYGF--YKVIQGNQARRRLGEEKLNARIAIAPVLEAEADRLMVRRRAQITEAERKIMANHKFYN-TD Morel2 LPRPGGFP-EIRYKRYVPKIGPSGLALFMCTLGL--YRTGQGNLERRELEREKVWSRIHLIPLLQAEADRDTYRREVAANEREAEIMKDVSVYN-SK Mucci2 LAPAQGYP-EIKYRRYLPKRGPSGMVILFCGFGF--YKVFQGNLERRELKRENLWARINLVPLLTAEADRDTYRRTEAAKAREAEIMKDVSVYNNTK Mydma LPPPGGYP-KLKFTQNLPKRGITGVTLMVMAVGF--SFVVKGNRKRRELGKEKMNARLSILPVLLAEQDRGILRRLKENFEAEKIIMKDVNIYY-TD Neucr2 MPPAGGYD-AVQYKRNLPPSAFKPKTLLIMVYGW--YHLFHGIREQRELAREKMWSRIHLIPALQAEEDRDLVRRHLADVQREKELLGDKKAYH-SD Orpsp11 ------------------------------------------------------------------------------------------------- Pench1 MPPTGGYA-QVQYKRNIPARGFKPAYYMIMAYGF--YKYFHGVREQRELAREKMWSRLHLTPLLQAEEDRDQVRRHYADKAREKELLGTDKVYN-SD Phybl2 LPPAEGYS-EVRYRRYLPKRGPSGLVILVSAFGF--YKLAVGNLERRELKRENLWARINVVPLLTAEADRDTYRRTQAANAREAEIMKDVSVYNNTK Picst3 LPPIGGYE-PVQWKRNLPSRGFRPSIYFLMAFGF--YRFYKGVDEQRELLRERQWARFYLEPLLLAEEDRNVARRYFSEKQRQRGSMSDEEIYN-DK Plicr1 MPPAGGFE-AVKYKRNLPFRGPGGIVVLVCTYGW--YQLGKGNLERRELQREKTWSRIHLVPLLLAEGDRDTYRRQQAALAREKEIMKDVSVYN-ND Polpo ------------------------------------------------------------------------------------------------- Pucgr2 LPPVGGYE-PVKFKRNLPIRGPSGSLIITCLYGF--YRYGQGNVEKRELKRENMWSRIHLVPILTAENDRDLFRRERARIDREREIMKDDSVYN-TK Punst1 MPPPGGFE-AIKYKRNLPARGPSALAILVCVYGF--YRVGLGNSEKKELVREKTWSRLHLVPLLLAESDRDAYRREQAAIAREKEIMKDVSVYN-NP Rhior3 MPPQGGFP-EVRYRRYLPKRGPSGLVILISAYGF--YKVAEGNLERRELKRENLWTRIHLIPLLTAEADRDAYRRSEAAKAREAEIMKNVSVYNNTK Rhoto1 LPPAGGFA-PIKYKRNLPIKGPGGAVVFICGFGF--WRVGLGNLEQRELQRERAWSRIHLTPLLLAEGDRDTYRREQAALAREREIMKDVKNYH-SK Rozal11 ------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------- Salro RPRPGGFP-TINYARNVPKRGPSGLAIVVFVLGM--YKINEGRRQRKLLHQENVNSRLVLEPFLNAEKDRRYIQQVAEQLEAESIIMRDVRVYN-TD Schco3 MPPPGGFE-AVKYKRNLPNRGLPAWAVMLSAYGW--YRIVQGNWEMREIVREKRWGRIHLVPLLMAEADRDAYRLQQAALAREKEAMKDVSVYN-NT Schpo1 ------------------------------------------------------------------------------------------------- Sorma MPPAGGYD-AVQYKRNLPPSAFKPKTILIMVYGW--YHLFHGIREQRELAREKMWSRIHLIPALQAEEDRDLVRRHLADVQREKELLGDKKVYH-SD Sphar MPPPGGFA-SVDFKRNLPRRGPQGTTIFAMVGGL--YFMGQENRKRRRLKLEKVANRIAIIPLLQAEEDRRFLREKTKFLADEKILMEGVHWYH-TD Spipu1 LPPQGGFPDTIQYKRYLPRRGPSGLVIFVMGYGW--YWVAKANAERRELRREKAWTRINLVPLLQAETDRDLIRRLEAAKKREGGVMENVPVYH-TD Sporo1 LPPSGGFN-PIKYKRNLPTKGPSGAIIFICTFGF--WRVGKGNLEKRELQREKVWSRIHLTPLLLAESDRDIYRRDQAALAREKEIMKDVSSYH-TK Stehi1 MPPSGGFE-ALKYKRNLPFRGPSGVMMLVSAFGF--WRLGKGNLERRELEREKVWSRIHLVPLLLAEGDRDAYRRQEAAKAREGEIMKDVSVYN-KA Tapde11 ------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------- Treme1 MPPPGGYE-AIKYKRNLPIRGPGGAVIFICAFGF--YRVGQGNLEKRELKRELAWSRIHLVPLILAEQDRDTYRRHEAAVAREKEIMKDVSVYN-TK Trire2 MPPRGGYE-PVQYKRNLPAKGFRPGIMLVMGYGW--YKLIGGIREANELAREKMWARIHLIPLLQAEEDRDQVRRYLADQKREKELLGENKVYN-SD Umbra1 LPPPGGYS-EVKYRRYLPKRGPSGLVIFVCAFGF--YRVAQGNLERRELKRENLWSRIHLIPLLTAESDRDAFRRQQAALNREAEIMKDVSVYNNTK Ustma22 LPPSGGYQ-PIRYKRNLPGKNLSGLTIFICAYGF--YKVGLTNLEQRELKRERAWSRIHLIPLLMAESDRDTYRRNEAQIAREKEIMKDVSVYN-TK Walse1 LPPPGGFE-AIKYKRSLPVKGPSGAVIFICTWGF--YKLGQGNLEMRELEREKTWSRINIVPLLMAENDRDIYRREKAALAREESIMKDVSVYN-GK Zygro1 ------------------------------------------------------------------------------------------------- [Cluster2773.fasta_al_trimmed; alignment length = 80] Allma1 RDLKIKTGVVKRVHKEYQKEAEQQQRIQKLIDS-GADDVRKQKEVLQETLVMIPDRLAAAFHELEGAVPELEAA-QAILA Ashgo11 TQLEIKVRALQRLIKEYQDELREQRRVELLKRDASVDELKKQIEVMQDTERLLPRKVQQFYNDLKDFVEDTADA-HNALK Aspfu1 -------------------------------------------------------------------------------- Aurde31 KPMKIKTGVVKRLLKEYKKELEDQQKVDQLIAD-GAEDIKNGRNMLEESKKMVPDRLQKAVTDLRELYDEYIKA-EEALE Batde5 RELKIKSGVVKRTHKEYQKEAEKQNRIESLIAK-CAHDVRKQREVLDETTQILPDRLVAAYAALASALEDVTAA-REIYA Botbo1 RQLKIKTGVVKRLTKEYEAEVEVLQRLDKFIEE-SAEDIKNGRKVLEEGMKMIPDRLSNYAKELVDIVADLAAA-EDALK Botci1 -------------------------------------------------------------------------------- Caeel KALRIKTGTVQRLVKEYEKQVVKEEKAAQLAAD-ATNVAKKSKDIVKETANMVRDRLQKAVADLRESIAEFVNA-KTLVD Canalb1 SPLQIKVNALKRLIKESKQEVAEQEHINQMKAN-NADELKKQIQVLEESQRMVPEKVAEYRQALKEFLEDVTEA-KELL- Cangl TQLEIKVKALQRLVKEYLQELKDQKHVDELKADSSVDDLKKQEEVLADTERLLPTKIKEFQDNLEEYLEDTKEA-KEAIE Capow KNIRIKTGVI--------SEAEDQQKVDQMR---QADNIKKQVEILDEAKAMIADRFETAFSEFKALLDEFRQA-QKVLN Catan2 RQLKIKTGVVKRLAKEYQKEAEKQQRIQNLIDT-GADDVRKQKEVLQESLVMIPDRLQEAFADLEEFTPEFEAA-SAILE Cioin -------------------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------------------- Coere1 RSLKIKSSAVERLVKEYIDDTAHQRFIEQLRKKDGVHDINKQKEVLEETLNMVPFHIRKAMQDLENLVKAIATA-KEALP Conco1 NQLQIKVNVVKRIQKEYLKEMVEVQKIDKMEAE-GKDEVRQVKQSLQETKDMLPDRLTQAVQDLTDYVPALQEA-MQIIQ Conpu1 RQLKIKVGATQRLLKEYGKEAEDQKKVDKMVAD-NADEIKNARRIQEESVRMIKDRLGKTVQDLRDLIEELIKA-EEALE Copci KQLKIKTGVVQRLVKEYKKEVEQNVKRDKFIAD-GAEDIKNAGKLVEESEKMVQDRLAAAVADLRVIVADFLKA-QEALE Croqu1 HQLKIKTGVLQRLIKEYHQELIEQTSLSSSKPL-PNDKLRKQKEVIEETKKMIPDRLSKSLAELQELVEELAKA-KGVID CryneH991 RQLKIKTGVVKRLHKEYIQEVEDQQVVEKLKAD-GANDIRAAERVLKDSEMMVPRSLEEAFQALEDLVQEFRDA-FSQLQ Crypa2 -------------------------------------------------------------------------------- Debha1 SSLQIKVNSLKRLIKEYQQEVAEQQFVNQMKSN-NADELKKQIQVLEESQRMVPEKIKKHKQALIEYVEDLSAA-KELIS Dekbr2 SPLNIKTSALQRITKEYEEELSENENVKSIQAKYDADTLKTAVKIRDETKRMIPNKIKEILEDLKDYLEGDAKA-KKAIE Dicdi RSLKIKIDALKRLEKDYKKEEQLQINVERFKADETKDDVKKQIEILDENKTMIIDRVTAFLVQFSEFLDDGSEIWKDSYD Dmel RQLVIKSGVVRRLTREYAKEVLTEQRLEKLRGD-GADVLRKQEEVIQECIMMVPDRLQKEYEVLEKYLDSYKKA-AEILK Enthi -------------------------------------------------------------------------------- Falba -----MLGACFPITADYLKDLNDARRIAAVPPSDDAPIIRQETQALEETERMIPDRLGAAVEQLDLFLPEAAATLEQVLQ Fomme1 RSLKIKTGSVKRLAKEYLKEIDELRKAEKLSSL-GGDEVKNANNLVNETVRTVELKLRNEVGGLRDLVESLVAA-KETLK Fusgr1 -------------------------------------------------------------------------------- Galma1 RQLKIKSGVVQRLAKEYRKETGQLEKLEKLVAD-AADDVKNARKMVDESNKMILDRLGKAVEDLQALIEDLVKA-EQTIQ Ganpr1 RDIKIKTGVLKRLNKEYHKEHEQQRRIDKMVQE-GKDDIRKQREVLEETTNMIPDRLVAAYKELEKLV------------ Gloin1 RDLKIKTGTVKRLFKDYHKESESQQHIDKLISE-GADDISKQKEVLQESLNMIPDRLKEAQKELQKLLEELKQA-EDILE Hisca1 -------------------------------------------------------------------------------- Klula1 TQLEIKERALKRLCKEYQEELEQQKHVKKLQSDPSVDDLKKQVEVQQDTERLLPEKIKQFRDDLDKYLEDLESA-KAALE Lacbi2 RQLKIQAGGVARLAKEYRKEADQLKKRDKLVVE-DAEDVKNATRMIEESEKMVIDRLGKAADVLSDLVPALVKA-KEALE Lenti61 KQLKIKAGSAKRLFKEYQKEEEELKKLDKYIEN-NAEDIKNTRRMLEESGKMITDRLGNVMQDLRELLEEVLKA-QETLE Malgl1 RQLTIKTGVVQRLAKEYRQEADEQARVKQYASQ-GKDDVKKQEEILRDCQQMVPDRLAAAISDLESCMDAYSTA-MSALE Mellp23 RTVKKSTQLQRKLIAEYRQELIEQTALSGFKKV-EGDKLKKQKEVIEETKKMIPDRLSKSLVELQELVEELLKA-KELIK Mnele RQLKIKTGVVKRLSKEYEKEVTDGEKLVQMKES-GQDDIKKYTEVVAESRAMVPDRLKKAVQDLDILLEEYKAA-QEIRE Monbr -------GVVEGLGKENFKEIAQQERIEKYKAE-GRDDVRKQYEVLEECKMMVPNRLEEEHKKLTDMVHR-APC-RRAAP Morel2 RDFTIKTNVLKRVTKEYTKEKEKQQRIDVMVAK-DPEEIKKQREVLEETLDMFPDRRKAARQDLANLVKEYEEA-VQALE Mucci2 SPLKIKTNVVKRISKEYLKEAETQQRIDKLIAE-GADDVRKQAKVLGETNQMIPDRLANAYQDLQNQVDELQEA-QTVLS Mydma RQLKIKTGIVQRLHKEYEKELIQQENILKMKND-GADDIRKQVEVKNESAAMIPDRLKKACDDLVNLLEEYIAA-QNVLQ Neucr2 -------------------------------------------------------------------------------- Orpsp11 RNLKIKTGVVKRLGKEYQKEYEQQQRIDKLIAQ-NADDINKQKEVLEETNMMIPDRLKVAHKELTDLVKEMIDA-QAVLK Pench1 -------------------------------------------------------------------------------- Phybl2 RELKIKTNVLKRIYREYAQEEQQQLRIDKLIAD-GADDVRKQKEVLEDTLQMIPDRLAKAYADLEDKVEELKDA-LQALE Picst3 -------------------------------------------------------------------------------- Plicr1 RQLKIKSGVATRMAKEYRKEAEDQKKLDKFVAE-GAEDIGNATRMLEESHRMITDRLGKAVGDLRDLIEELLKA-EEALE Polpo RNLKVKIDSLKRLEKDYQKELEEQKTVQQFKNDSTKDDVKKQVEILDENKTMIIDRLTDSVNILTDFLTESLEQYNEALE Pucgr2 RPLKIKTGVVERLIKEYKKEYDNQLRIEKVKQE-TPDNIRKQKEVLDETIKMIPDRLSKAIEELADLVEELSKA-QQVLT Punst1 RQLKIKSGAAKRLLKEYRNEAEQLQKRDKLIAD-GAEDVKNAGRLVEESNKMVVDRLGSTVQELRELVDDLLKA-EDALE Rhior3 SQLKIKTNVVKRIHKEYQKEAEQQQRIDKLIAD-GADDVRKQKEVLEETFQMIPDRLAKAYQDLEAQVNELQEA-QTTLS Rhoto1 RQLAIKTGVVNRTVKEYRAEAVELKRADAMEAA-GEDEVRQQRKVQAESQQMIPDRLAKAVAELEELVDEFRKA-EAALK Rozal11 KTLSVTSGTVKRIMKDYEKEYKIQSKIDKMKME-NKDDIKKQIEVLEETEKMIPDRLERALADLNNLLEELSNA-RTIQQ Sacce1 TQLDIKVKALKRLTKEYQQELKDQEHVAKLKEDKSVDDLKKQEEVLDDTKRLLPTKIREFKEDLEQFLEDVSDA-RSAIT Salro RQIKIKTGVVKRLGKENLKEIAQQERIQKYKDE-GRDDIKKQYEVLEECKMMVPDRLKKAHDELTAMLEEYKAA-KQMLA Schco3 RQLKIKTGAVSRLWKEYRKEAEEQKKVDKMIAD-AGDEIRNAQRILAESEKMIEDRVGKAAVDLREIVEEYLKA-QEVLQ Schpo1 RSLVIKTNVVKRIIKDAHIDINEAERVQSKIDN-GEDEIEHQKFVLKKHLEALPDRLRNATNDLESISEYLEKA-KEVIE Sorma -------------------------------------------------------------------------------- Sphar -------------------------------------------------------------------------------- Spipu1 RKLKVQTGAVKRISKDYEKEAAKQQRIDKLVAD-GADDIRKQKEVLEETNQMLPERLAAAYKELADLVEEVLAA-QTVLQ Sporo1 -------TSIRRLVKEYEQEAQQNKTADKMQQN-GDDEVKQARRIHADSMQMIPDRLAKAISELQDLV-EF--------- Stehi1 KQLRIKSGSAKRLYKEYRDEVEDQKKLDKLVAD-GAEDVKNAKKMLEESKKMVVDRLGKTVADLRDLVEQLIAA-EEALE Tapde11 RSLKIKTGAVKRLAKDSQKESESERRLATLKAN-GGDEIRAQDKVIADADQMIPDRLAAAIEELEELTEELKSA-NEVLA Thetr RELILPANVIQRPAQAVDEESEREARVRKYEAE-GRDDVNKQKAVAAESHMMIADRLTAAVEDLEEVMAAVAAA-NDALQ Treme1 KQLDIKKGSLQRLWKEYLKEVAEAQQLDKLKQE-GADDVRNAAKIQQEAIKMVWRSTGQALRELIVFLEEVTAASQAEIN Trire2 -------------------------------------------------------------------------------- Umbra1 RELKIKTNVVKRISKEYGKELESQQRIDKLIAD-GADDVRKQKEVLEETVQMIPDRLAAAVQELSTMV-----V-RKLFK Ustma22 RQLTIKTG-------EYLVEAKQQERIAQFIDA-GRDDVKQQRSVLADTLKMIPDRLQLATDELLNYVSELVAA-KQLLT Walse1 RQIKIREGVVKRLTKEYKQEVVDGETMNKISLD-DENKKNNQSKLIEESKKLVIDRLTKAIDELEKIK------------ Zygro1 TQLEIKVRALQRLVKEYQEELKEQTHVESMKADKDVDDLKKQVEVQQDTEKLLPTKIEEFRDNLEEFLEEVGDA-HGAID [Cluster2791.fasta_al_trimmed; alignment length = 148] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 VKIKIGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKINLGTDVIFSIMDLGGQREFINMLPLVAVAIIFLFDLTRPETLTSIREWYRQARGFNETAIPLLVGTKYDLFAQVMGAPLVFCSTASSINVQKIFKVIIAKAFNL Aspfu1 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDL Aurde31 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTITVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDVFARAMKASLIFCSTSASINVQKIFKIVLAKAFDL Batde5 VVIKVGMMGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTIAIRTEITFSIWDLGGQREFINMLPLVAIAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDYFAKAMRAPLIFCSTSHSINVQKIFKIVVSKAFDL Botbo1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLVGTKFDTFAKAMHAPLIFSSTSASINVQKIFKIVLAKAFDL Botci1 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDL Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 VALKIGLIGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMDKKIQIRTTITFSIWDLGGQKEFINMLPLVAVAILFMFDLTRKSTLNSIKEWYRQVRGFNKTAIPFLVGTKYDQFGSAMKAPVIFCSTSHSINVQKIFKIILSKAFDL Cangl VDIQVGLIGDAQVGKTSLMVKYVQNIFDEEYTQTLGVNFLKRKVSIRTDIVFSLMDLGGQREFINMLPIASSVIILLFDLTRPETLNSIKEWYRQALGLNDSAIPILVGTKYDLFAQVMDAPLIFCSTAKSINIQKIFKVALAKIFDL Capow VVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTICIRTEITFSIWDLGGQREFINMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKNAISFLIGTKFDIFAKAMKAPLIFCSTSHAINVQKIFKIVLSKAFDL Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFARAMKASLIFSSTSHSINVQKIFKIVLSKAFDL Coere1 IVLKVGMLGDAQIGKTTLMVRYVFGEYDPNIVQTLGVNYLEKSVHLRTRVRFSIWDLGGEREFLNMLPLVSAAILFLFDLTQRRTLNSIEQWYRQARAFNNTAVPILVGTKYDQFARAMRAPLVFCSSLRSINVQRIFKIALSKTFDL Conco1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFAKAMQAPLIFCSTSHSINVQKVFKIVLSKCFDL Conpu1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDTFARAMHASLIFCSSSASINVQKIFKIVLAKAFDL Copci VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDQFARAMHASLIFCSTSASINVQKIFKIVLAKAFDL Croqu1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDL CryneH991 IVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKAISIRTEITFSIWDLGGQREFVSMLPLVAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPVLIGTKYDQFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDL Crypa2 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDL Debha1 VALKIGLIGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMDKKIQIRTVITFSIWDLGGQKEFINMLPLVAVAILFMFDLTRKSTLNSIKEWYRQVRGFNKTAIPFLVGTKYDQFGHAMKAPVIFCSTSHSINVQKIFKIILSKAFDL Dekbr2 VTLKVGLVGDAQVGKTSLMVKYVENCFDEIYTQTLGVNFMERTIRIRTEITFSIWDLGGEAEFTNMLPSVAVAVLFMFDLSRKITLRSVKDWYRQARGFNRTAIPFLVGTKYDSFARAMNAPLIFTSTCASINIQKIFKIVISKTFDL Dicdi VVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDVFASAMKSPLIFCSTSHSINVQKIFKIVISKAFDL Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------- Enthi IKLKIAMVGDAGVGKTSLMVKYVEGNFDEDYIQTLGVNCMEKTISLKKEVTFSVWDLGGQREYITMLPMVARVILFFFDLTRVMTLNNIKDWYKEARAHNNSASCILVGTKYDLFAQAMKASCVFCSSSQGINIQNVFKVSLAKVFGL Falba VVLKIGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTVQVRTEITFSIWDLGGQREFVNMLPLVAVVLLFLFDLSRKSTLNSVKEWYHQARGFNKNAIPFLIGTKFDQFAKAMRAPLIFCSSARSINVQKLFKIVLSRVFDL Fomme1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDTFAKAMHASLIFCSTSASINVQKIFKIVLAKAFDL Fusgr1 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPILVGTKYDHFAKAMRAALIFSSTSHSINVQK------------ Galma1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDQFARAMHASLIFCSTSASINVQKIFKIVLAKAFDL Ganpr1 VVLKVGMVGDSQIGKTSLMVKYVEGSFDDDYIQTLGVNFMEKTISIRTDITFSIWDLGGQKEFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDQFAKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDL Gloin1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDQFSRAMKAPLIYCSTSHSINVQKIFKIVLSKAFDL Hisca1 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLG-----------------------RTANGN------RQGRGSNKTAIPFLIGTKYDHFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDL Klula1 VKVKVGLIGDAQVGKTSLMVKYVQNVFDEEYTQTLGVHYLERKVVLGTDVIFSIMDLGGQREFINMLPLVAVAIVFLFDLTRPETLNSIKEWYRQARGFNDTAISILVGTKYDLFAQVMKSPLIFCSTQSSINVQKIFKVVIAKAFNL Lacbi2 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDQFARAMHASLIFCSTSASINVQKIFKIVLAKAFDL Lenti61 VVIKVGMLGDSQIGKTSLMVKYVEGHFDEDYIQTLGVNFMEKTITVRTSITFSLWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDTFAKAMHASLIFCSTSASINVQKIFKIVLAKAFDL Malgl1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDL Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYVQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFARAMKAPLIFCSTSHSINVQKIFKIVLSKAFDL Mucci2 VVLKMGIIGDAQIGKTSLMIKYAEGAYDTEYTQTLGVNFMEKTILIRAEITFSIWDLGGQKEFASMLPLVAVAILFTFDLSRKSTLNSLREWYRQARGLNKSAVPLLVGTKYDEFAKVMKAPLVFCSTAESINVQKIYKIVLAKVFDL Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDL Orpsp11 -----------------------------------------------------------------------------------------------------TAIPFLIGTKYDQFAKAMKASLVFCSTSHSINVQKLFKIVLSKVFNL Pench1 VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPFLVGTKYDHFAKAMKASLIFSSTSHSINVQKIFKIVLAKAFDL Phybl2 YVIKLGIVGDAQIGKTTLMVKYVEGHYDTEYTQTLGVDFMEKTLMINTEVTFSIWDLGGQREFVSMLPLVAHAILFIFDLTRKSTLNSIKEWYRQGRGLNKVAQPFLIGTKYDEFARAMKAPLIFCSAAESINVQTIYKIVFAKTFDL Picst3 VALKIGLIGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMDKKIQIRTTITFSIWDLGGQKEFINMLPLVAVAILFMFDLTRKSTLNSIKEWYRQVRGFNKTALPFLIGTKYDQFGRAMKAPVIFCSTSHSINVQKIFKIILSKAFDL Plicr1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDTFARAMHASLIFCSTSASINVQKIFKIVLAKAFDL Polpo VVVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDVFASAMKSPLIFCSTSHSINVQKIFKIVISKAFDL Pucgr2 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLIGTKYDHFAKAMRAPLIFCSTSHSINVQKIFKIVLSKAFDL Punst1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDTFAKAMHASLIFCSTSASINVQKIFKIVLAKAFDL Rhior3 VILKIGIVGDAQIGKTSLMIKYAEGAYDPEYVQTLGVNFMEKSISIRTEITFSIWDLGGQKQFASMLPFVAVAILFTFDLSKLSSLNNLREWHRQVRGITMTAVPLLVGTKYDEF--------------------------------- Rhoto1 VVLKVGMVGDSQIGKTSLMVKYVEGSYDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVSMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSKAMKAPLIFCSTSHSINVQKIFKIVLSKAFDL Rozal11 VFVKVGMVGDSQIGKTSLMVKYVEGTFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQKEFINMLPLVAIAILFMFDLSRKSTLNSIKEWYRQARGFNKSAIPFLIGTKYDQFAKAMKAPLIFCSSARNINVQKIFKIVLSKAFDL Sacce1 VEVQVGLVGDAQVGKTSLMVKYVQNIYDKEYTQTLGVNFLKRKVSIRTDIIFSIMDLGGQREFINMLPIASSVIIFLFDLTRPETLSSIKEWYRQAYGLNDSAIPILVGTKYDLLAQVMNAPLIFCSTAKSINIQKIFKIALAKIFNL Salro ---------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKYDQFARAMHASLIFCSTSASINVQKIFKIVLAKAFDL Schpo1 VTIKVGMIGDSSIGKTSLMVTYVQGSFDEESTQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPMVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAVPILIGTKYDHFAKAMKASLVFCSTSHSINVQKIFKIVLAKVFDL Sorma VVIKVGMVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFAKAMRAALIFSSTSHSINVQKIFKIVLSKAFDL Sphar VIVKVGMLGDAQTGKTTLMVKYVEGSFDEDYIQTLGVNFMEKSITIQTEITFAIWDLGGQREFINMLPLVAVAILFIFDLSRKQTLNSIKEWYRQARGFNKTAIPFLVGTKYDVYSDAMKAPLIFCSSSHSINVQKIFKIVLAKAFDL Spipu1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDQFAKAMKAPLIFCSTSHSINVQKIFKIVLAKAFDL Sporo1 VVLKVGMVGDSQIGKTSLMVKYVEGSYDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVSMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHFSRAMKAPLIFCSTSHSINVQKIFKIVLSKAFDL Stehi1 VVIKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISVRTTITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSVKEWYRQARGFNKTAIPFLIGTKFDTFAKAMHASLIFCSTSASINVQKIFKIVLAKAFDL Tapde11 ------MVGDSQIGKTSLMVKYVQGIFDEDYLQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIREWYRQARGFNKTAIPFLVGTKYDHFAKAMRASLIFCSTSHTINIQKIFKIVLSKAFDL Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 IVLKVGMVGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVSMLPLVAVAILFMFDLTRKATLNSVKEWYRQARGFNKTAIPVLIGTKYDTFSKAMHAPLIFCSTSHSINVQKIFKIVLAKAFDL Trire2 ------MVGDAQIGKTSLMVKYVEGSWDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQGRGFNKTAIPVLVGTKYDHFAKAMRASLIFSSTSHSINVQKIFKIVLSKAFDL Umbra1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 VILKVGMVGDSQIGKTSLMVRYVEGSFNEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLTRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDHYSKAMKAPLIFCSTSHAINVQKIFKVLLAKAFDL Walse1 LYLKTALVGDSSIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTISIRTEITFSIWDLGGQREFVNMLPLVAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKFDIFAKAMHAPLIFCSTSHSIHVQKIFKIVLSKAFDL Zygro1 VEVQIGLVGDAQVGKTSLMVKYVQNVFDEEYTQTLGVNFLKRKVSIRTDIIFSIMDLGGQREFINMLPIASSALVFLFDLTRPETLTSIKEWYRQAHGLNEGAIPVLVGTKYDLFAQVMDAPLIFCSTAKSINVQKIFKVALAKIFSL [Cluster2795.fasta_al_trimmed; alignment length = 282] Allma1 PAPANGPECSPTPA---PAARPAAL---------TWRGGSYGTGTLSRSEPTWWARTQARNEFAEDVALARKDARRQARAGGG------------GAEEGGG---------------------VVDAATRAQQLATE-LEQLQLLPEEAMFLA--GMLHIASVTLDD------HAAARFAAYHAWRSRDPPWVPKCGLKYGADFVLY-SKGPNHGHAPFA--VRIVPVKTAD------------------QVG--------QQDDATTA--------DRNRE Ashgo11 -----MAYVHPLPI-EPPPLIAHNYTVTGEQ-MQLWEHGFFGTGQLSRSEPTWQARTVDR-HKLEQVTQLRRKQRLEFKRERASRKRLELRRQGVL--------------ESEILEQERDRELQEASTGPSPVRAEDAIEKLELMPVEALFLTALPVLHA---DAPALPQIE-RLCRLYAAYHHYRSHG--WCVRSGIKFGCDFLLY-RRGPPFHHAEFSVMVLAPDER--------TWY--STVARVVGGAQKTLVLAYVARRY----VHELVYRRGKNRE Aspfu1 PAHRARPHRFPLPL-DVPPLIPHNVHVTDKA-IQLWEMGFFGKGTLSRSQPSWLEREKKR--TNEELTRQRRTERRELKLERARKVAIEKKAEAAARES-GAAVTLEKFSRSKEQENKEQ---ESDS-AEAQETSQEEEEHLQLSNEEAFFLAGLGVLHVYDIPHTSLKPDD-PFMISYIVYHHFRSLG--WVVRSGVKFGVDYLLY-NRGPVFSHAEFAVVVIPAYEHSYWSETSDSWWWLHCVNRVQAQVKKSLVVCYV---DSKTHVREMLIRRNRTRD Aurde31 QNK-AGSYAHALPV--I-------VWVVHEH-SRLWTRGFFGKGSLSRSEPTWLSRQT--SRAAELVTAKRREERKAFKEERARAAAAEE-AEAAFA-V-GA----PFVPGAVEEGPSAEPGA-EDDLT--------DLEYLQLTLQEAFFLAALDTLKVLDLSLHD-RFDN-PFLVNYAVYHHYRSLG--WVVKSGIKFCADLLLY-KRGPVFTHAEFAVVVCPVYEDDADRSTSPTWSWLSTIGRVNSQVQKTVILTYVSTDAVNSPVREVVLRRARMRD Batde5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Botbo1 PGK-SQAYAHPLPL--LL------VWITNKD-TFLWQRGFFGKGNLSRSEPSWLSRRIN-QLTAEEVTARRRELRKQFKTERAQAAAAAE-AEAIFAAT-GE----EAVPSKATFQAKGQSAAVDSVVTDE-VDDAITMEHLQLTLQEAFFLASVGCLNIIDIAPSA-WFDN-PFLVSYVAFHHYRSLG--WVVKSGIKFCVDLLLY-KRGPVFHHAEFAIVVIPVYEDPEDRKSSPTWSWLSTINRVNSQVKKTLILTYISAEELKSPVREVTIRRARMRD Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel -------VAGRVPV-AL-------VEIFDTA-SRIHEMSGIGQ---------WLK---------DERKESRGVSRSCFSQSCGE----------------GK-----------------NEWAE--------------ARTLVLTPIETALLSDWKIINVVKLSDEE------EFGKVFSVFRFLKMNG--WIVTSGHTFGCDYLIY-CLGAEFYHSSAGVLIADVIDP----------RRLLTLTRILSHNKKALIVATT--------VKISTMKTNRCNE Canalb1 -----MGYSQPLPI-TLPNLYPHNFKVIDES-MLLWRQGFFGKGILSRSEPTWEKRTITRDLAMEDITKKRREERKFFKLERARELELKKRQGIIT--------------EVEEMNKLEKIQVRDKQENEIHIRDEDELEFLQLQEVETFFLKALQRIDIVNDSLLDPTSNN-QFIIEYIAYHYFRTNG--WCVRSGIKFGTDFLLY-KRGPPFTHAEFCVLVMTKDSK--------DWFQIAAKARVIGSVKKAFVLCYIKQNEEDIDISEVIYKRSRTRD Cangl -----MAYKFPLPI-HPPVVSQYNLLVEDQD-MKLWNNGFFGTGQMSRSEPTWKFRTEKRTMDLEKVTEIRRIQRLAFKKERLRGELSESRSQNISA-------------ETQIIEEHRSDQLKNNLKLAPETRDEDLLESMELMPVEAIFLTALPVLDI---KINDIEELK-VLVRKYAAYHHYRSLK--WCVRSGIKFGCDYLLY-KRGPPFQHAEFAIMVLDHTES--------TWY--SSVARVASGAKKTLILCYIQGNL----VAEVTYKRGKNRD Capow QHRAPKAYAMPLPIAAASQSQSQSVAVSDAA-MSLYQQGFFGKGSLSKYEPDFHEMVRKIAMTAKQRQAERKSKRDKQRKAKFDAAKAAKSHEQRLASR---IASGLQVNEASAAASGSDDDSSDELGEEEEEEDEEETEHLQLALEEAMFLQALGCLDVCNLSIDE------RFVERYVAYHYCRSKG--WVPRPGLKYGVEFVLY-RRGPVFFHSNFTVAIQLLHEDPVSLDSAPTWPTLLALARTTDQVKKETLLVNVDEQELASPVREVLLRREQEL- Catan2 --------------------------------VD--------------------------------------------------------------------------------------------------------TEPMVLMPDECIFLASHNRLAIRFVASAP-SPTN-------------RFAG--WAVRCGAKFGVDLLLY-AKGPQFGHSKYAVVVVPTASGANKRHGGA--RWLRQLNGLS-----KLLLCYVPSSRTHMPVRCVEVGRGKNRE Cioin -----------FPV-------------------------------------------------------------------------------------------------------------------------------------------------------------------TYCAYHHFRSKG--WVPRDGIRYGGDLVLY-RKGPPYYHASYIVIIVSVDAETLQETVFRSWPTMSGQLRLATSVSKEVMLCHVKSDSCDV-VKETIVSRTKERE CocheC53 --RKPRPHSKPLPI-DVPAFVPHNIHVTDAS-IRLWEQGFWGKGSLSRSEPQWLVAEKRR--TSTEVTQSRREERRQFKLERAKREAIEQRQE-------GK-----------EATVDEDATTS----TEEANTKLEELEHLQLTPEEAFFLSVLGVLDVVNYPAWYIAPDN-PFLLKYVVFHHFRSLG--WVVRPGIKFAVDYLLY-MRGPAFTHAEFAIMIIPSYSAPYWNENPGDWWWFHRVNRVQTQVMKTLMLVYVSATELGGFVREFVFKRSRNRD Coere1 RTATLQMWPTLVPI----------VHIINEG-QELWKDGCFGKGILSRSSPTWQQRYQREERYIEDITQRRREARRQIRENTNEHEEDIT----------GS--------NNAISAQDTDLNVS--------------MEPVQLSPFEALFLSCLEALDVSHLHTEL---KSDDFDLKYAAYYYYRAKG--WVVRSGLKFGSDFLLYGKGGPARSHSQYSVVVRKLEQQSEDTA---SWQHMFGLSRVCTQVRKSLIICYVKHQDSILPIQEYLFKRNRK-- Conco1 ----MKN----LPLNYL-----NNVEVRDIK-MKIWFGGFFGKGIYSRSSPQF--------------------------------------------------------------------------------------ETLWLNIEELIFLNNLGILKLYLIEYSQ------ELVCNYCAYYYFRSKK--WIVKSGLKYGTKYVLY-RDGPTNKHSEYSVNITLSSITRSNKA---PLVDLIGSIRLCGSVQKKYMICFV--------VHLVQFSRERTRS Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Copci SRK-GGAYAHPLPL--LS------VWVSNED-SMLWRRGFFGKGNLSRSEPSWLSRQLNIQLTSEEITARRRAERKQFKLDRARAAVAQE-AEEIFEKE-GRALSGPAIPSAATWKPS-QPIE--RAATE--GEEEEEVEHLQITLQEAFFLLNMDCLTVLDMSLKDLQFDN-PFLINYAVYHHYRSLG--WVVKGGIKFCVDYLLY-KRGPVFSHAEFALVVMPVYEDEQGQASSMTWSWLSTINRVNSQVQKTLVLVYVSTNVLNSPIREVVLRRARMRD Croqu1 EPSQSKAYNNLLPI-KLSSL----IMIDFDH-VQLWRSGFFGKGSLSRSEPTWIQRAKNRKLTAEELTAKRRIERREAKIEKAKERELKEKVENL--NE---VESETWAEQTASSVPSTRPK--DAIVN---------LEHLQLKPVEAFFLAGLGSLTVEVFSIDE-RPDN-PFVVSYVAYHHFRSLG--WVVRDGIKFCVDWVLYGSRGPVGGHAEFAVCVIPAYEDPEEEP---SWQWLSTVNRVCSGVKKTLVLAYVGAEEMRT-VKEVVIKRSRMRD CryneH991 ----PRAYGTPLPI--L-------VWITDKM-MDAFQKGFFGKGSLSRSEPSWRARRVG-TLAAEQMREKRRLERKQFKIDRAQLDAAKK-AEAIVA-A-AKAETQSQLPDPLNLTPQTRPDANTAVATEAEEDLFDEMEHLQLSIEESLFLSAIGVLRVYDLTPTSLLPDN-PALVGYAVYHHFRSLG--WVVKDGIKFCVDWLLY-RRGPVFSHSAFACVIIPVYTDTHDQAVSPSWKWMNTVIR-------NVIAVYITSNLKLADIREVALTRTRRRD Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 -----MGYANALPI-ILPQIYPHNFKVNDED-MRLWKQGFFGKGTLSRSDPSWKTRTNRRDITSEEITRMRREERKKFKTERSKDLELKQRQNNIS--------------ELQTLEEVRLENPNNQALTEA-LRIEDQLEYLQLQKTEVFFLRALNVINI--LSLSQISPNN-SFILEYVVYHHYRSLG--WCVRSGIKFGCDMLLY-KRGPPFSHAEHAILIMS-DSH--------DWSSISSISRVIGGVKKNLVLTFISSYS---CITEILYRRSRNRD Dekbr2 -----MSFTRPLPI-KVPPVYPGNFKVTNKD-ANLWESGFYGKGSLSRSEPTWIARAEKREITGEEIVKYRRQLREAYKKDRNE--LLRERNYKLSGDK-DK--------ERTKLSERRPPSSSN----QNNLRAEDRIEYLQLTHCESLFLSEVKVLS----TIRLASPQN-DFLIQFVVYMHYKSLG--WCVKSGLKFSSDYVLY-QRGPPFHHAAFAVTVMNNTSK--------NWTHFGSIFRVVSAVKKTMILCYVFLDGRD-PIQEIVYKRSRTRV Dicdi -------------------FKRNNVKIIDQG---LYKHGSYGKGILSRSFPIFDNIK------------------------------------NSSITG-SG------------LNNKRNENQTTTTTTQQKTTHLENVEYLQLSLCEAFYLISLGCLTILRMTIQE------SFISKYITYHYFRSLG--WIPRSGIKYGCDYILY-KLKPDLIHAQYGIIIQNRNEQNDNNNNNNSWDELSGINRVSESVAKGIIVFNINNGDINKLVNMWELKRNRTRA Dmel --FTFEC--TPLPSGQD-------VEIVDEQ-AKLHDNGCFGKGSKSRGGPA--------------------------------GDENET----------G-------------------------------------ME-------ESCFLA-LNVLDITNMDFCM----NEKFVENLASYVYLKSKN--WVIKSGIKFGGDFLIY-KQSPRLYHASFLVIV-----QPGDT----S-KNLKGVQRVAETSDKDVLLLTVPKKISSSRVTETIVRRSKQQ- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba RQPQPKRALEVMPC----------IDLVEER-SRLLSHGYFGISV------HWLQ--------------QRSRQRKRFRQAHSG--------------------------PAAFAGPPR----------------------IVLSLEEALYLCVLEVLTIFRMSASE------SFGPRYAFYVYARGRG--WTPKDGLKYGVDFLLY-LQSPALFHATFSVLVTPVWNAPSAITSGCDWRTVARLVRISNQVSKDFSVAFV--------VQWVPLRRERTRT Fomme1 NAK-GAAYAFPLPL--FPSDIP--VWISNKD-AMLWRRGFFGKGNLSRSEPSWLARQINQ-MTAEEVREKRRMERKQFKLDRARAEAALE-AEKAFAAT-GEAESSVVIPSAATWKPSPNPDTEGEQLTEQGGDILDEMEHLQLTLQEAFFLITMDCLTIADLNLQQSRFDN-PFLIHYVVFHHYRSLG--WVLKNGIKFCVDYMLY-KRGPVFSHADFSLVVCPVYEDPSDREGSPTWSWLSTINRVNSQVQKTPVLTYVPSDILSSPIREIVVRRARMRD Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 AHK-GGAYANPLPL--LP------VWVSNAH-SLLWRRGFFGKGDLSRSEPSWLARQINIQLTSEEITARRRAERKQFKLDRARAAVAEE-AETIFATE-GRALSGPAIPSGATWKPSQQPENPDEADT-------EDVEHLQLTLQEAFFLLNLDCLTVLNMTLQQLQFDN-PFLVNYAVYHHYRSLG--WVVKGGIKFCVDYLLY-KRGPVFTHAELSLVVLPVYEDPEDQKSSSAWSWLSTINRVNSQVQKTLILVYVSSDVLLTPVREVILRRARMRD Ganpr1 -------HFHTIRI----------AWVTSED-ATVWTEGHFGKGTLHRSEPEY-------IIYGGSKPRRRRKESA------------------------GT------------------------------------AEILQLSGVETMFLAAQARLNVEDLSSSETAQDP-RFPLLYAVYKHYRKQG--WVVRSGAVYAADYVLY-RTGPAYDHSEFVVTVLSLETGVDEHHSAP----LFNLSRMSFQVKKDVLVCFV--------VREVVVRRERAR- Gloin1 ----------------------------------LWKEGFFGKGNLSRSEPTWFWRNSNNKLAAEQITEQRRIVRKRNKKGRVNQNMSKV--------------------QQITKEEVQQDEEQEQTLT--QEE--ENIETLMLTTQEAFFLCGLGILDIYDLSAEE----S-GFIIRYIVYHYFRSLG--WVVRCGMKFGVDYVLY-EKGPVFKHAEYAVIILPIH--TSQNFDNSSWSWMMNLNRVCVQVKKSLVLCYVTTTYLTITVRHVLVKRSKLK- Hisca1 NHLPPRPHRFPLPL-HVPPLIPHNVHVTDKA-IRLWEMGFFGKGSLSRSEPSWLDREKNR--TSEEVTGKRRVERRERKLERARKEAIAEKAEAQLRNCRGDAHPNEQPQSS--IPRQYN-ERSSAQPTPHTDK-QEHQEHLQLSNEEAFFLVCLGVLQVYDLPATSAKPDD-PFLLSYVVYHHFRSLG--WAVRSGVKFGVDYLLY-NRGPVFSHAEFAVCLLPAYSDPYWTATAETWWWLHCVNRVQAQVKKSLVLCYVTGANGENDVREMTIKRNRSRD Klula1 RQVLTMSYKHALPI-EAPSVWKH-ILVCDWQ-MKLWEHGFFGTGQLSRSEPNWQARTMSR--NLEHVTDVRRRQRLEFKKLRAEAKKLEMRQKGIV--------------DEQFIEQERDKELAEK---SMQIRDEDLLESLQLMPVEAIFLSAVPVLKI---TLQQFQDIK-KLIHQYVAYHHYRSKG--WCVRSGIKFGCEYLLY-RRGPPFQHAEYGIMVLDANQS--------TWY--SSAARVVGGAKKQFVLCYVQSKY----IHELLYKRGKNRD Lacbi2 PFK-GGAYANPLPL--LP------VWVSNDH-SMLWRRGFFGKGDLSRSEPSWLARQLNNQLTSEEITARRRAERKQFKLDRAAAAVHEE-AEVIFETE-GKALSGPAIPSAATWKPA-KPEE-----T----ELEEEVEHLQLTLQEAFLLLNLDCLTVLDMSLKQLQYDN-PFLINFVVYHHYRSLG--WVVKGGIKFCVDYLLY-KRGPVFHHAEFALVVIPVYEDPEDQQVSVAWSWLSTINRVNSQVQKTLILVYVPESILESPVREVILRRARMRD Lenti61 SPK-GGGYAHPLPL--VPE-----VWVTNKD-SMLWRRGFFGKGDLSRSEPSWLARQVNAYMTSEEVREKRRAERKQFKMDRAAARAAAE-AEAAFA-E-GR----AFIPSGATWKPHQ-----SEISSE--VVEELEVEHLQLTLQEAFFLVNLDCLTVLDMDLRRNRCDN-IFLVNYAAYHYYRSLG--WVVKGGIKFCVDLLLY-KRGPVFHHAEFAVVVIPVYEDPADKESSPSWSWLSTINRVNAQVQKTLILTYVSADLLSSPVRDVVLRRARMRD Malgl1 -------Y----------DQGDAL----------LWTQGFFGKGSLSRSEPTWASRKIAE-ITAEQMTQRRREERRLLKIERARVRAGIQ-PDGITALG-GE----------ELWRGDEKPIVEDIQSTAEEEEEEDGVEHFQLTMIEAFFLAMLGCLEVHDLSLDTVRPDN-PFLLSYVVYHHFRSLG--WVVKSGTKFCVDFLLY-KRGPVFSHAEFSVLVIPEYENEQDREGSPSWIWFSMMNRVNTQVQKLE-------------------------- Mellp23 ESIQSKPYSNLLPI-NLNTY----ISVTGHQ-FQLWRCGFFGKGNLSRSEPTWLQRAKNRKLTAEELTAKRRIERREAKIEKAKERE-KERLEGIEVNE---IKETDQIE----TKPSE-----DSIVN---------LEHLQLKPEDAFFLSGIGCLQIE-FSINE-KPDN-PFIVSYVTYHHFRSLG--WVVRDGIKFCVDWVLYGSRGPVGGHAEFAVCVIPVYEDPNDQE---NWKWLSTVNRVCSGVKK---------------------------- Mnele KAKTNKR--GPRPVVQL-------VIITDHD-AAVYMSGCYGKGSISKGAPT------------------------------------------------G-------------------------------------SEHLILSPCEAMYLI---ALVLIQWGKSD----NIGFCEKFIIYKHFRDKR--YTVRSGIKYGGDFMLY-TGDPNTTHAAYVVKV-----VSEEL----LWTDVNALRRVSESVAKECVLSYVQYDDRNHPVSHVLLKRERDRE Monbr AKKSNRR----------------GLRLSKSEWIQKWTIRGLSTWPEEAPRPRPWTRTRDGRKFKPSVELHAGDAKKPTRKRGGKNAAAATVPENEAVEMDGESSHEKRIAAADDTHPAKQSKAESEGATEDPDAEADAREYLQLSLEESWFLAALGCLNVKS--LSD----------VLASMHPNRG----WVPKTGLKFAADWLIY-RQGPTFYHSSYSIVVRTAWADTFDP----SWHYLSAVSRVSGQAGKEAMVAYVSMSDATRPLKEILAKKRRSEE Morel2 --RNNAGYSVPLPLPALQQQQKQPVWIHEKD-MELFRQGFFGKGTLSRSEATWKERTAGSGVSLEEITRQRRVERAQLKMEKLVVQGNAS------------SSNTSSTNASGFTTPVSDPQLNETVSS---------EEHLQLSLEEAFFLVAVECIAVSEFSIQEISPDN-PFIVRYAAYHHYRSLG--WVVKDGLKYGTDFLLY-KKGMIFGHSQFGIRVVACKSAPLNLHSSPSWQWLLALNRVISQVQKTVILCHVSKQQLSHPIVEVGIKREKNRK Mucci2 ------------------------VWVQKQS---LYRHGFFGKGDLSRSEPTWLKRTVEQ---LEEITVERR--RKRRQKNTGN-----------------------------------EDNVN----T--SIELLDVVEHFQLDLYEAFFLVAVNALSIMNLSIAD----NPSFHSHYAAYHFYRSLG--WVPKTGSKFGVDFVLY-QSGPSFRHADYAVAVIPL---VNNRLEEPSWDWLLRLSRICTQVKKTLILCYVDTTLFSNLIRQVIYKRQKNRE Mydma --PRRKT---PFPV-PITRK----VCIFRGD-LTLYRLGFFGKGILSRSRPQFEKYNDVLLLQFAKIQKERL--RQHKSWKCNNNHIVPE--------------------EKVDFIPPQDDDMEQLTMNTKRIKLEDDLEYLQLTLEEAFFLSALGCLSVENMSITK------DFIQMYIAYHYFRSKG--WVVRTTNIYGTDFLLY-KDGMPFYHASYSVCVRLVDEENLNMIDGMSWKDLSSISRVNERVAKDVLFCYVKVEQLAVPVIETVLRREKYRE Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 -----------MSI---------NVVIKDNS-INCWYNGFYGKGNLSRSTPNWSERILRDKIPENTLDDNFSSGIKRFKQWNKKIDISQYLIQSFFNDL--------------------KDNCEKFIKS---------MEYLQLDLEEAFFLKALNCISIKDLSIDD-NPSD-PFILKYIAYHYYRSQG--WIVKEGLKYGVDYILY-QKGPIFSHSEYAISIIPVMND--------TIHEINCTNRVCNQVLKKLVYCYIKDIDLNSPIYEIRMKRDKTRN Pench1 PPRAPRPHQFPLPV-NVPPVIPHNIHVTDRS-INLWQMGFFGKGSLSRSEPSWLAREKKR--TSEEITRLRRTERRELKLERARKLAIEEKAEAAAREA-GVAATTEKFSKARELAAQNQPETSSTSPSDNLDS--DDEEHLQLSNEEAFFLASLGALQIYDITTSALLPDD-PFMISYTVYHHFRSLG--WVIRSGVKFGTDYLLY-NRGPVFSHAEFAVVIIPSYTHPYWSETEESWWWMHSVSRVQAQVLKSLVVCYV-------SVREFLIKRNRTRD Phybl2 -HKHPKT---PLPI-LLA------VWLERDH-ALLYDAGFFGKGSLSRSKPTWHERHSSQ--FLEQITVDRR--KQRREKKRLDS----------------------------------DDRMDHDTYS--SAEILDLIECLQLDLLEAFFLASLNALEICDLSVKE----N-IFNAHYAAYHYYRSLG--WVPKNGAKFGVDFVLY-QSGPRFRHADFAVVVLPQN-ETSDKTTSSSWKWLLGVNRVCTQVKKTLVLCYVDISLLRNCIQQVVLKREKNRE Picst3 -----MSYSRPLPI-ELPTLFPHNFKVLDES-MALWRCGFFGKGTLSRSEPTWKARTIKRALSMEEVTNKRRDERKKFKAERSRELELKQRKGEIS--------------ESSQLEQLRLIDFKSKDSFETDLRFEDLLEFLQLQAIETFFLKAVNVIR-VNFSTKQLKPTN-KFVLDYVVYHHYRSLG--WCVRSGVKFGCDMLLY-KRGPPFIHAEYCILVISNDDK--------DWFEMAAKARVIGTVKKTFVLVYVSAYS---DVTEILYRRSKTRD Plicr1 ATKGGGGYAYPLPI--LPE-----IWVPNKD-ALLWRRGFFGKGDLSRSEPSWLARQINAHLTSEEIREKRRAERKQFKLDRAQAAAAAE-AEAAFA-E-GRPDGTRVIPSAATWKPAP-----NELPSE--LEREIEVEHLRLTLPEAFFLQNLDCLTVLDLNLLQHRFDN-PFLINYMVYHHYRSLG--WVVKGGIKFCVDYLLY-KRGPVFHHAEFAIVVCPVYEDPADRDTSPEWSWLSTINRVNSQVQKTLILTYVSTDLLGSPVREVTVRRARMRD Polpo EGVADAGQEYAKKV---LSYKKDNVKIPSEG---LYHRGCFGKGTLSRSNPIYHQIKQQL--------------------QQSHTEEEDE--EDDSSRG-GV-------------NLKRNDNQQ-----YQRIN--DN-EDMQLSLYEAFYLLGLGCLTILRMTIEE------RFLPNYIAYHHFRSTG--WIPRSGLKYGCDFVLY-KLRPELVHAQYQVVVQYLNEYTTSSSSSSSWVNLGRMNRVSESVAKGTIIFNINERNKNDPQQQQQLFTNQNQS Pucgr2 EPAHSSAYSKLLPI-SLNK-----VWLTSR---TLWQQGFFGKGSLSRSEPTWLQRAKNRKLTAEELTAKRRVERKESKIQKSKQLA---------MNT---VATSS------ETKPA--PKQKEKIDD---------LEHLQLMNEEAFFLSGLGCLDVSLLTILEIRPDN-PFILSYVVYHHFRSLG--WVVRSGIKFCADWVLYGSRGPVGGHAEFAVCMIPVYADPVETM---SWRWLGTVNRVCSGVKKTLILVHV--DEFETDIKEIALKRARMRD Punst1 --K-GGAYAYPLPL--VVES----VWVIDAD-AQLWRGGFFGKGNLSRSEPSWLARQINAGLTSEQVTAKRRAERQQFKIDRAKAAVAAE-AEKAFE-E-GREAAKASIPSAATWKPSTDADA-AEAMEE--SVIDDELEHLQLTLPEAFFLSALDCLTIIDLSLSDLRPDN-PFLLHYVLYHHYRSLG--WVVKGGIKFCVDYLLY-KRGPVFHHAEFALVLCPVYEAPADRSSSPEWSWLSTINRVNSQVHKTLILVYVDPEVLRSPIREVTIRRARMRD Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 ENLNSSSYAQLLP---LKQ-----VWVQDAS-MMLWKQGFFGKGFLSRSEPSWKRRVQNRRLTSEEITALRRIERKGTKLAKKLDQE---------------LAASAAAS-SVGSAPGT-PSTSDSRLEKAEDQDADEAEHSQLQPEEAFFLVAIGCLALTGLTILD-RLDS-PFFLSYAAYHHYRSLG--WVVRSGVKFCVDWVLYGQGGPVGGHAEFAVVIVPTYVTPADSASNPSWRWFHTINRVCSGVKKTLVLLHVPSEPNWVAMREVVVRRGRMRD Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 -----MSYKYPLPI-HPPELILHNITVQDKQ-MLLWNNGFFGTGQFSRSEPTWKARTEAREMTLEKVTQQRRLQRLEFKKERAKRELLELRKKGGHI-------------ENILLEKQRLKQTEQQQDIESNLRDEDNLESLELMPVEAMFLTALPVLDI---SPACYKDIH-SFVRSYVIYHHYRSHG--WCVRSGIKFGCDYLLY-KRGPPFQHAEFCVMGLDHDVS--------TWY--SSIARVVGGAKKTFVLCYVSNNF----VGEVLYKRGRNRD Salro RAAADGSLVHP------PKRKSGNVKVHRDM---LHYQGCFGKANLSKSEPMHHKVVRDVQAKKREEKAMRRRERKEAHKQQAHVEERDKGVENDEAEG-G-AATTTSTDTAAPAEEEREEQQQQPTTTQQQDRTRDG-EVLQLSLVEAFFLKGLGCLRILDMSTVE------QFVQRYVVYHHLRSAG--WVPKSGLKFAADFLAY-RQGPAYYH------------------------------------SRGMDVY--G-------------------- Schco3 PGK-GGAYGNPLPL--LPE-----VWVTDRS-VLLWQRGFFGKGHLSRSEPSWLARQVNDKMTSEELTARRRSERKQFKLDRARAAAAAE-AEAAFKER-GEALSGPNIPSAATWRPSQNPSARENITTNTFSTDADEVEHLQLTLQEAFFLAALDCLTVYDLTLQDLSPDN-PFLVNYAVYHHYRSLG--WVVRGGIKFCADFLLY-KKGPVFTHAEFALAVIPSYEAPGER---TTWTWLSTINRVNAQVMKTLVLVYVPAGALLGPVREIVVRRARMRD Schpo1 -------YKDALPISLAPPIILTNCVVTDEA-IKFWTSGFFGKGNLSRSEPTWHTRTKRSDLVAEEVTARRRFQRKQFKAQRAYNRARERLLEN------GK-----------------EEDAESRVSE---------VEHLQLTFPEAFFLASLGVLRINYFELLPIEPDN-KFLTELAAYFYFRQQG--WVVKNGTKFSVDFLLY-KKGPVFSHAEFAILLIPCVGN--------QWHEVHCLNRVIAQVKKSLILCYVNQASMNEWIRCVTLRRSRNRD Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ATPTTKAHAEPRKAKCL-------AYTSD---------GGLQSGDNSTSQP----------------TDMRTIEDRKFEQYKHT----------------GR--------EAGCAVSTKQDTVEQSLVA---------VEREVLGLEETFYLVGLQCLDLYRMTIQD------AFIPRYTVYHHYRACG--WVPRSGLKYATDFVLY-KMGPIFTHSSYNVLI------RTENAPEGGWGKIQNLQRMTEGVAKDTVLAWVTTFDCTTPVDEYIIRREGT-- Spipu1 QDSLQSTFQNPFPL----------VWILQGK-AQLWRGGFFGKATLSRGEPTWWKRMARDSTEGESLAARRRAMRTAQRRNVPQSEPKSTTSMSSFSDG-----------DSLVSTPYA-------------------PERYQLTPEEAFFLAGLGILAVKELEPCE------EFAVRYAAYHYYRSQG--WVVKSGIKFGTDYVLY-RRGPIFRHSDYAVVVVPSVSDTAHRDTLPTWVWALSVNRVCAQVNKRVLLCHVTRKELADPIWDVCIGREKTRD Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG--WVVRSGVKFCTDWVLYGPGGPVGGHAEFAVLIIPTYVNPKDSIDSPSWKWFHTVNRVCSGVKKV------PSLPLYLA--------SERRD Stehi1 PNK-AAGYAHPLPL--LPEP----VWVTNKD-SRLWTRGFFGKGNLSRSEPSWLARQVNASMTSEEVTAKRRAERKQFKVDRARAQAAAE-AEAAFR-E-GREETKANIPSAATWKPSS-----ASVST--------AVEHLQLTLPEAFFLCALDCLTVLDMTLQDLRPDN-PFLINYVFHHHYRSLG--WVVKNGIKFCVDYLLY-KRGPVFHHAEFAFVLMPVYEDEEDKTSSPTWQWLSTVNRVNSQVQKTLILAYVSKEVLGSPIREIALRRARMRD Tapde11 -------YKKPLPVHNVPALT-QNVWITDAS-ASLWYCGFFGKGQYSRSEPSWFVRTQRARLTSEEVTARRRVARADMKAERARKEVLEARAEGRLPGP-DT-----------------DAETE-----EEVESASVTLEHLQLTLYEALFLSALDALDIYQMEKNTIMTDC-HFLIQYAVYHHYRSLG--WTVKPGIKFGVDWLLY-KRGPVFSHAEFSIIVMPA-------ARTAPWWWLHTLSRVNGQVKKTVILTYVELGKVNVEIREVSLKRSRNRD Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 ----LGGYGTPLPV--L-------VWVTRDH-IDLFRRGFFGKGTLSRSEPTWRERRLG-GLTAEQVREKRRIERKQFKIDRAALSAAKA-AEAVLT-S-GQSEDGSS--DLTTLTPQTRPDTNAPQPTEDEEDLAEEMEHLQLALEEAWFLAALGVLKIYDPPPSAVRPDD-PFLVSYVAYHHFRSLG--WVVKPGIKFACDWLLY-RRGPAFSHSAFSCVVIPVYSDLEEQAESPSWKWMNTIMRVNSLVQKTVILVYVPPSTQLSGVREAALTRARRRD Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 --ASPKKHKDPLPI-KL-------IRITDLD-IQLYCKGFFGKGNLSRSEPTWSQRIAAEKQFLENITEARR--KQRRAT-RMSN----T--------------------PPLTSSPSQSEDCNEVRNN--YYEILDT-EHLQLSLVEGFFLAGLGCLEIMNLSIIEIGYDN-PFIVKYVAYHHYRSKA--WVVKDGIKFGTDYIIY-QRGPAFHHGEFAIIIIPSYHETSNKQEN-SWSWILGMNRVCSQANKTLVLCYVTTVHCLSPVTEMAMKREKTRS Ustma22 ----GAGYSKPIPI--ASDDADNDIWVEDDEGIRLWQRGFFGKGNLSRSEPTWRQRKVNE-MTAEQLTQQRREERKALKIERARVRAGQQ-PDGILALG-GEADIERQVEAQELWTGQEVPDIVEVKANAAQDNVEDDFERMQLSLVEAFFLSMFGCLDIHTLELDDARPDN-PFLIDYVAYHHFRSLG--WTVKTGVKFCVDMLLY-KRGPVFSHAEFAVVVIPSYEDAQDQESSPDWTWFSTINRVQSQVLKTLILAHVRPETLATPVKEVAIRRARMKP Walse1 QKNNTAHYANPLPV--LR------VWVINRD-IRLWTRGFFGKGSLSRSEPTWNDRQ---QPTAEEITSKRRVERNKMKIERAKTEAQLA-AEAALA-----IKESPPVPTSRGFEPSSEPDEQ----------EEQEAEHLQLTLQEAFFLAGVGCLRIIDMSNRQ-RLDN-PFLVNYAVYHHYRSLG--WVIKSGIKFCVDMVLY-KRGPVFHHAEFAVVICPTYEDEADKSTSPSWQWLNTINRVNSQAKKTLILAYV--ENIDEPVKEVVIKRARNRD Zygro1 -----MGYKYPLPI-HPPPLIPHNIVVKDSQ-MNLWENGFFGTGQLSRSEPTWKNRTHNR--ALEKVTQHRRLLRLEFKKQREKQELLELRRKGGTI-------------EKELLEQQRSQQS-AEVLPEETIRDIDLLESLELMPVEAMFLTALPVLDI---TAKDYEDIH-QFISQYVVYHHYRSHG--WCARSGVKFGCDYLLY-QRGPPLEHAEFCVRILNSNDI--------NWY--SSLARVVAGANKTYVLCYVQGNY----VGEITYKRGKNRE [Cluster2797.fasta_al_trimmed; alignment length = 347] Allma1 TIFAVATAQG-KAGVAVIRISGPDAVATLRDPEPLDRAM-VVSFPG-PRSFTGEDIVELHAHGGPAVVKSILGALAKLFRMAERGEFVQRSFNGKLNLTEVEGIKDLVNAETDAQRRQALRQSE-GELGNLYEEWRTIIVLSMGHMEAMIDFGED--EQFEDGVWESTDGRRGEILRSGIRTTIFGPVNSGKSSLLNYLARRRVAIVSDIPGTTRDVVESLVDIGGYPVLLGDTAGLRTADPVERIGIEIAHERLTDLKIAVVDTVVVLNKVDMLVSVKNGLDQFIRMLLTNERHRSHLVR-CVDHLGRFLDVVLAAEELRRAAQCVGAITGVDVEEVLDVVFRDFC Ashgo11 TIYALSTPMGQKSAIAVVRVSGTHALRNLYSPVFLDSAL-TLFFEQ-PGTFTGEDILELHVHGGKAVVAGVLDAIGALIRYAEAGEFSRRAFNGRFDLTEIEGIGELIDAETETQRRSAISSFR-GQNRLLFAGWRQQIVDNIAQVAAIIDFGDDT--EIIDAILEGVRVTRSTILQSGIRLSVLGAPNAGKSSLVNCITKDDTSIVSSIPGTTRDAIDVPLDINGYKVILTDTAGVRAHDPIELIGIARAQERTSDIVLLVVDRLVVINKSDLVISCKQGLDALVHALAISARARDILRQDVLAGLDGFLEVDVASESLRSAADGIGTITGVGVEEVLGVVFSNFC Aspfu1 TIYALSTAPG-RAAIAVVRVSGSACVRTLYDPTVLDAGALVLYFPG-PKTVTGEDVLELHLHGGPAIVKSVLAAIAR-VRYAEPGEFTRRAFNNRLDLPQIEALGDTLTADTEQQRRLAVRGAS-DALSRRYESWRQQLLYARGELEALIDFSED--QYFPEDFVRSVNASKGELLRNGIKIALLGAPNAGKSSLLNRIVGKEAAIVSTEEGTTRDIVDVGVDLGGWYCKLGDMAGIRSEGAVEKEGIRRARARASDVVVLVISIVVAINKCDRLISCNENLQRFLRGLGVTHRQSSNLQR-CMQHLDDFLDVVMAAEHLRFAADTLAKITGGDVEDVLGVVFEK-- Aurde31 TFFALASPPG-KAGVAVYRISGPDARCTVVDPSALDDGL-AVFFAG-PRSYTGLDTLELHLHSGRALCAAVLGALARVCRPALPGEFTRAALNGKMDLTQAEGLRDLLDAETDAQRRVARAVAG-GKTRKTMEDIRAGIIGALARVEALIDFGEG--EDIEEGTWDDADGRRGEILRAGIRVAIFGPPNAGKSSLFNFFAQRDAALVTPLPGTTRDVLELSIDLAGMPVILVDTAGLRTTDVVEKMGIERARTAIADLSMCVLSSLILYNKLDLAASVQTGMDAFLAGLITHARHRHHLEA-ALDCIDAFLEVVLAAEELRYAANELGRVVGVGVEDVLDALFKDFC Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 TIYALATPPG-KAAIAIIRVSGPAARCGVVDCELLDDGM-CVFFEG-PKSFTTEDTVELYVHSGRAVLAAVLSSLSRVTRPAERGEFTRRAFAGRIDLTEVEGIRDLVEAETEAQRRLAVHAAR-GTTRARFEEIRAEIIRCLAMVEALIDFGEG--EDIEEGVYQQADNRRGELVRSGIRIAIFGPPNAGKSSLLNFLVQREAAIVTPLPGTTRDVLELSLDVGGMPVIVCDTAGLRDTDVVEKIGVERAAKAVADVSLCVLSSLVLLNKTDLVGSVKKGMKEFTNGLITQERHRVHLQR-ASEYLDAFLDVVLGAEELRYAAVEIGMVSGVGVEDVLDVVFGEFC Botci1 RIVDVLQREG-LSNIRRMELSGPKSVRTLYEPNILDSDALVLYFPA-PNTVTGEDVLELHVHGGSATVKAVLSTISQ-IRYAEPGEFTRRAFNDRLDLAQVEALSDTLSAETEQQRRAAVRGNS-GKLGRTYEAWREQLLYARGELEALIDFSED--QHFPAELLSNVASHRGELLKKGIRIALLGPPNAGKSSLLNQIVGREASIVSQEAGTTRDIVEVGLDIRGYLCTFADTAGLRTQGDIEREGIRRAKSKASDLIVALAS-MIVINKSDSVISCKDSIGHFVDEMGVTERQRQLLTA-CSAHLLDFMDIVLAAEHLRSAANCLSRITGGDVEEVLGVVFEKFC Caeel TIFALSSGTL-PSAIAMFRVSGSQSYTKLYDSKIIDEAM-AVYLPG-PKTFTGEDTAEFFLHGSQAVAVKFASCLAGIVREAKRGEFTRRAFNGKLSISEVRGIDRLIKSRTEKERNAAFGQMR-GGVRAI--EIRKQLIQILSKLFVIIDFGEH--VNL----LREAAWDGAERAQRGLDIVLYGRPNSGKSSILNQLAHDDVAIVSSIPGTTRDSLETIIQINGVRCRLTDTAGVRQKDVIEAEGIRRAQKRIADIICVVVDVIIAKNKSDL-VSTNAGCKQLQNCLASYLLDADLLRR-CSFELESAVDAAIMCSHLEVALEQIGELTEIVTESVLDGIFSKFC Canalb1 TVFALSTKFG-KSAIAVVRISGPQSVRKLYSPVFLDEAL-TLFLPG-PKTYTGEDLLELHLHGGVAIIKSVLQSIKKLIRQADRGEFSKQAFNGRLDLTELEGINDMINAETESQRLASLASSS-GQTKIEFMKWRNEIINQMANLTMIIDFGEDH--DITDRMIRDVKVKSSQILLNGIQLALLGPPNAGKSSILNILANKDAAIVSEIAGTTRDILDIPLEIGGYKVVVGDTAGIRSFDSIEQEGIKRAKQRSADFVIVVLDMLIVLNKQDLFVSCSTGIDNLQKLLIVSSRVQDILENDILFGFKEFYDVLVATDCLRQSVDGIGKITGIDLEEILDVVFSSFC Cangl TIYSMVTPRA-KSAVSVIRVSGDKALRGLYN-ELIDRAL-VLYFKS-PGSFTGEDVVEFQVHGGRAVSESVLSAIGSLIRMADRGEFSRRSFNGKADLTGLEGINTLINADTEAQRRAAMGSFT-GKNKALFNRWRDIAIQNSAQLTAIIDFSEDS-DFAYTAVMAEVRVTKASIVENGINMTLLGAPNVGKSSLLNQIASDDISIVSDIPGTTRDIVSSIVNINGYKVNLFDTAGIRVDDPIEKMGIEKAFKRISDICICVIDIIFVVNKIDIVVSCLKGIDELVTVLIVSDRVKEILEKDVLYGIDQFLDIVIATEHLRYVIDGIGKITGIGLEEVLDVVFSKFC Capow SIYALATAPG-RAGVAVVRLSGRAALCRLVHPEHIDDAI-VLWFPG-PRSFTGEDVAEFHIHGGRSIIEALFEALSELTRMADAGEFTKRAFNGKIDLTEVEGLADLINAETRAQRQQALRQLN-GAMSRTFEEWRRTILKSMAHVEGNIDFAET--EDIEENVMQSADSRRGERLRSGVSVAIVGAPNVGKSSLLNIMSQRPTAIVSATAGTTRDILEVPLDIGGYPLLLCDTAGMRDSEEIEQEGIKRARARACDLRLCVFDSLPIINKIDTVLSCKSGVSVLLERLITQWRHRTQLQT-CVAHLDHFLDVAIAAEHLRQAVRALGQITGVDIEEILDVIFRDFC Catan2 -------------------------RAKLHSPNVLDHAL-IVRFPG-PKSFTGEDVVELHAHGGPAVVKSILSALGSLFRMADRGEFAHRAFNGKLDLSEVEGLKDLVNAETEVQRQLAINQSS-GALSSMYERWRTTIVSSMGHMEALIDFAED--EQFEDGVWDNTDNRRGEILRQGIRTTLFGAPNAGKSSLLNHLAQRSVAIVSPIPGTTRDIVETTVDIAGYPVVVGDTAGIRPADAIELMGMHRARDRITDLRVCVMDTLVVLNKADAVVSLTSGVLELNQVLLTNARHRAHLEA-CQAALGRFLDVVLAAEELRLAATSIGRITGVDTEAVLDVVFSDFC Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 -------------------------LRKLYAPTILDSGALVLYFPA-PRTVTGEDVLELHVHGGPAVVRAVLAAIPE-IRYAEPGEFTRRAFNNRMNLPQIESLGETLSASTEQQRKLSVRGTT-SSLAKRYEKWRKLLLEARGELEALIDFSED--QHFPAALCASVNAVRGELLRNGISVALLGAPNAGKSSLLNRIVGRDAAIVSQEAGTTRDVVEVGLDMGGWLVKIGDMAGLRRAGAVEQEGIRRAKQRASDVLIVVQDVIFAINKSDQIISCKENILAFLTTLGTTERQRLLLSE-CLSHLSAFLDIVVAAECLRSAADALARITGGDVEEVLGVVFEKFC Coere1 MVNQNHTKIG-KLHKKKIR------VGKIFHPNVLDSGI-SLWFPG-PKSYTGEDMVEFHIHGGIAVVNSVMEALGTIVRMAEAGEFSRRAFNEKMDLTKLEGVADLINAETEAQRRLAVRQAH-GELYKMYETWRQRIVGVMAKIEAFIDFSED--ENIEEDIYSEVDKRQGEIMRNGVSLSIVGPPNSGKSTLLNRLAQRQVAIVSPIAGTTRDIVETTMNIGGYPLVVRDTAGLRSSDVIETEGIRRAVESAADIRLFMLDTFVVLNMADGVLSCASGWECLMQLLLTKIRHRQHLKN-CIKHLNVFKMVVLGAEELRKASKALGQITGVGIEDVLDALFSEFC Conco1 TIFAVASGKG-KCGVSVIRVSGPKAYSPIYDPSLIDRGM-LVKFQE-PNSFTGENVVEFHVHGSVAIVKKLLEVLNGFFRSAESGEFTKRSFNGKLDLTQVEGLADLLEAETEVQRKLALKQSE-GELGQLYQRWRYGIIDILSQLEAWIDFSED--EELDPILLKTCDGRKGEILREGIKLAILGPPNAGKSSLLNWLVKREAAIVSPIAGTTRDLVEVRVEIGGFPVIIVDTAGLRDSDIIEVEGMKRALKQAADFNLLVLDTIILYNKSDLYVSCETGLNEVLGHLITQTRHKLLINR-AVEKLEHFIDPVLSVEDLRGATMEIGKLTGITLDHILDQLFKSFC Conpu1 TIYALSTPFG-KGGVAVIRVSGPDARCQIVHPRVLDDGL-AVYFKG-PKSFTTEDVLELHLHSGRAIISGVLNALSALCRPAEAGEFTRRAFGGRLDLTQVEGLKDLINAETEAQRRMALEAAG-GVARSQFESLRTKIIKCQVFVEGFIDFGED--VDEQEHMLSEADNRRGEILRSGIRLAIFGPPNAGKSSLLNFLAQREAAIVTPIPGTTRDVLELTLDLGGLPVIVADTAGIRKTDLVESVGIERAQNFVSDVSICLLSTFFLLNKSDLICSLMTGTKAFLDGLITHARHRHHLEK-AVEHLQDFLQIDIAAEELRYAAAAIGKVSGIDVEDMLDVLFRDFC Copci TIYALGTPPG-KAGVAVVRVSGPDARCRIVHPETIDDGL-AVFFKG-PKSFTAEDTVELHLHSGPAVIAAALAALSTFCRPAAPGEFTRRAFNGRMDLTQVEGLKDLIDAGTESQRKIALRAAE-GAIREKFDELRQRIISALAKVEALIDFGEG--EEIEEGVYEDADHRRGELLRSGIRLAIFGPPNAGKSSLLNILARREAAIVTPIPGTTRDILELALDIGGLPVIVADTAGLRKTDTVEQIGIERARKAVSDVSICVLSTYFLLNKADLMSSLAKGFEVFLSGFITRQRHRENLEN-ATRFLESALDIVFAAEELRYAANAIGKVTGIGVEDVLDAVFRDFC Croqu1 NIFAPATPTNTKSALSIIRVNGPDALRKVFCHNILDPEAIVMNFPH--SNLTS--TFEFHLHGSKSIIKSVIESLSKLFRIAKPGEFTLRRF-NELELNRLLGIKNLIDAETEEQRKMAIHQFESGQFSKIYQNLRKNLLDCMSLCEVILDFSED--GSIDKLIWNQIDSQRHEKVINGIRISLFGSPNVGKSTLLNW-IGKEASIVSPYPGTTRDIVEVSIDFHGFPLILYDTAGLRETDPVEDIGISRAQAK--------------------------------------------------------------------------------------------- CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 TIYALSSGQG-RAGIAVIRVSGPACVRTLYDPHILDSEAVTLYLPA-PKTVTGEDVLELHVHGGPATIKAVLGAIPR-IRYAEPGEFTKRAFHDRLDLSQVESLSDVLAAETEQQRRAAVRGNS-GLRGQTYDAWRSDLLLARGEIEALIDFSED--QHFPRELLHNVAGQRTELLKNGIRIALLGPPNVGKSSLMNLIVGREASIVSREAGTTRDIVEASLDIGGYLCTFADTAGIRTRGAIEEEGIKRARLKASDVTIVLAS-IVVVNKCDCVISCKAGIHHLTRKLGGTERQRQLLAQ-CREHLEAFMDIVLAAESLRCAGDCLARITGGDVEEVLGVIFEKFC Debha1 TIYALSTKLA-RSAIGVIRVSGSQSVRKLYS-ILLDEAL-TLYFKS-PKTYTGEDILELHLHGGTAIIQSVLNAIKKLIRYAENGEFSRRAFNGRFDLTEIEGIREMIDAETESQRVAALSSLT-GDTKKTFAKWREEIVKNVALLTTVIDFGEDH--DIVAQLFDTVKVLSSEVLMKGIKLILLGPPNAGKSSLLNYLANKEAAIVSDIAGTTRDVIDVPLDINGYKVIVGDTAGIRTTDKIELEGIKRAKLKSGDLVLVVL-IVVVLNKQDLLVSCITGISELMCVLVISARAQDILRNDVIYGIEQFKDVVLASESLKQAAEGIGKITGIGVEEVLGVVFSSFC Dekbr2 TIYALSTAPG-KAAVAIIRISGPASVRKLFDPKLIDESL-CLFFKG-PHSYSGEDLSEVQCHGGRAVINAIMKAVSSLIRYAERGEFSMRGFNGRFDLTEAEGINELVNAETEVQRLSVLSSTN-GDTRKLFNSWRKRILHNVALLTTVIDFGEDH--EVVNHLFDKVKTQKSQILMDGIKMTLSGPPNAGKSSILNILADDEKAIVSSIAGTTRDAIDIPLAINGYKVILGDTAGIRNA-EIEQEGIKRAHRRTADLNLVIL-SLIIVNKSDLMISCKTGIQELVNTLVISKRARDILEKSVLQGFKDFKDIVLATEGLRFSMEGIGKITGIGVEEILSTVFSEFC Dicdi TIYNLSSGVG-KSGVAIIRVSGPQALSTFYNPEQLDKGM-FIWFPS-PNSFTGEDVVEFHIHGGRAVIYETMEAIGLITRPSEQGEFTKRAFNGKMDLTQVEGLSDLLDASTSFQKKIALKQMQ-GSISEFYLSLRKDLIRASAYMEAFIDFGDD--AELDPEIVDQSDGKRGERLRDGANIAIVGPPNAGKSSLINLLTNRKASIVSPIAGTTRDIVEVILDIDGYPVIIGDTAGLRNSDQIEIEGIEMAKDRFSDIKLFLFDTIIIFNKSDLLISCNNNIKDLLNLLLTRLRYKQHLSD-CVESLDRYLDVVLASEELRSAILSISEITHVNIDDLLDIIFKDFC Dmel TIYSLSSGHV-KCGVSVIRVSGPQTLKSFYHPEMIDRGL-LLWFPG-PASFTGEDSCEFQVHGSLAVIAAMLDALGKVLRPAEPGEFTKRAFGGKLDLTEVEGLADLIHAETEAQRKQALLQST-GALARLYDNWRRRLIRCAAHLEAYIDFAEE--EQIEGGIILQLDQRQGELLRDGVRTVIIGAPNVGKSSLLNLLCQRSVSIVTDQAGTTRDIIETMHNFGGYPVVFSDTAGLRRYDSIEQEGMQRAKNCLSDLILLLAELQLVANKTDTLISCHKKMPVFLGSLITNTRYRQQLER-CIENIDIFLDMAIAASKLRNSVRCIERITGISCEDILDVVFKDFC Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba TIYAPATAAG-RAGVAVIRMSGPLSVRSLRDPELVDRGL-VAFFPG-PGSFTGEDIAEFHVHGGPAVVEGLLSALSNAVRWALPGEFTRRSFNGKLDLTQAEGLADLLAANTQAQRRQALRLAG-GAARRAATAWRGSISRALAHLEALIDFADD--NDFEQETLSVARSHCGALIRDGLRVSLVGSPNAGKSSLLNAIAEREVSIVSPFAGTTRDIVEAPLSLGGFALLVSDTAGLRSADPVEREGIRRAQAKIAHLRLAVIDTLVAFNKVDLLVSCTTGVDALADALLSHPRHRDYVSR-AVSHLKVALDAVLVAEECRAAAHALAGLAGLAPDDVLDIVFAEFC Fomme1 TIYALATPPG-KGGVAVIRISGPDARCAVVDPDELDDGL-AVFFKG-PHSFTTEDILELHLHSGRAVISAVLSALGRLLRPAERGEFTRRAFGGRLDLTQAEALRDLIEADTEAQRRVALSSAR-GSARVRFESMRNEIIKAMAMTEALIDFGEG--EDLEEGVFDNADSRRGEILRSGVRLAIFGPPNAGKSSLLNHFAGREAAIVTPIPGTTRDVVELTLDIGGLPVVIADTAGLRKTDMVERIGVDRAKERVSDIALCVLSTFILLNKRDLCVSLTCGVERFVSEFVANARQRAHLEA-AQEYLDAFLDVVLAAEELRYAANAVGKVTGIGVEDVLDVVFREFC Fusgr1 TIYALSTAQG-RAGIAVIRISGPSCVRSLYDPLILDSEALILYFPN-PKTVTGDDVLELHVHGGSATVKAVLAAIPK-IRYAEPGEFTKRAFNNRLDLAQIESLSDTLAAETEQQRRAAVRGNS-GSLGRQYEAWREQLLLTRGEIEALIDFSED--QHFQAELLQNVGSQRSELLRNGIRIALLGPPNVGKSSLMNLIVGREASIVSGEAGTTRDIVEASLDIRGYLCSFADTAGFRSQGAVEEEGIRRAKQRASDLVIVLAS-LVVVNKQDAVISCKEGIQAVITRLGVTERQRQLLIK-CRQHLEDFMDTVLAAEYLRYAADCLARITGGDVEDVLGVIFEKFC Galma1 TIYALSTPPG-KGGVAIVRVSGPDARCRIVHPSLIDDGL-AVYFRA-PYSYTTLPTLELHIHSGRALISALLSALSSFLRPAEPGEFTRQALGGRLDLTQVEGLHDLIEADTEVQRVWALGGAG-GETRAEYDSLRKQIIHCLAQVEALIDFGEG--EDIEEGVYEQADSRRGEMVRSGIRMAIFGPPNAGKSSLFNYLANRPASIVTPIPGTTRDVLELTLDIGGLPVIVADTAGLRETDVVEGIGVQRGIDAIADISLCVLATYFLFNKSDLVASLVTGAHAFVQGLITRARHRVHLES-ACKFLEAFLDVVFAAEELRYAAQAVGRVTGIGVEDVLDALFRDFC Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 TIYALSTAQG-KAGIAIIRVSGPNARKKISHPEIIDHGL-ILWFPG-PNSYTGEDTVEFHIHGGTSVVRGILDALGCIFRHAEAGEFTRRAFNDKYDLTEIEGLADLLNAETEAQRRQALRQAQ-GGLKILYENWRKQLIENTAFLEAIIDFGED--ENIEDGVLERVDNRRGEILRDGIHVTILGPPNAGKSSFLNYLAQRRAAIVSPIPGTTRDIIEISLNFGGYPIIISDTAGLRPSDVIEIEGISRAKDRIADIKILILSTYLVLNKCDLILSCLTGFDEFQKSFITQARHREHLRD-CLKALENFLDIVLAAEELRFATHALGKITGVDVEEILGVIFQQFC Hisca1 TIYALSTAPG-RAAIAIVRVSGPACLRTLFDPSILDR-AVVLHFPA-PNTVTGEDVLELHIHGGPAVVKAVLNAIPR-IRYAEPGEFTRRAFNDRLSLPQIEALGNTLSAETEHQRRLAVRGTS-GSLAFRYERWRQQLLYARGEMEALIDFSED--QHFIEEFVSSINASKGELLRSGIRVALLGAPNAGKSSLLNRIVGREAAIVSSEEGTTRDIVDVGVDIGGYFCKFGDMAGLRSGGAVEQEGIRRAKARASDVVIVVLSMIVAVNKFDKYISCRENIQKFLGELGVTHRQSSNLQK-CVQHLNDFLDIVTAAEHLRFAADCLAKITGGDVEDVLGVVFEKYS Klula1 TVYALSTPSNQHSAIAIIRISGTHSIRSLYDPTLIDEAL-VLYFPQ-PRTFTGEDLVELHLHGGKAIIKAALNSIQGLIRMAMPGEFSRRAFNGKMDLLKLESINNMIHSDTELQRLSALHG---NQTVDIFHEWRQEIIEQIAKLTAIIDFGEDI--ETIDSIVNGAKLDRMAVLNDGIKLTLLGEPNSGKSSLVNEISQDDVAIVSDIPGTTRDSIDVMMDINGFKCILTDTAGIRQGDSIEIKGIDRSKKKSSDLVVLVIDLIVVLNKSDLAVSCLTGLEPLVKTLTVSNRVKEILSTDILFGLDQFFDILIACESLRIASDGIGKITGVDLEEVLDVVFSKFC Lacbi2 TIYALSTPPG-KAGVAVIRVSGPEARCRVVHPEMLDDGL-AVYFRA-PHSFTTEDVVELHIHSGRAIVASVLGSLALLCRPAEPGEFTRRAFGGRLDLTQVEGLKDLIDAETDAQRRIALQAAG-GASRAKFDELRKGIINCLAQIEALIDFGEG--EDIEEGVYDEADHRRGELMRSGLRLAIFGPPNAGKSSLLNFLAQREAAIVTSIPGTTRDILELSLDIGGLPVIVADTAGLRHTDVVESIGVERARNAVTDIALCVLSTFFLFNKSDLLASLSTGTEAFLDGFITRARHRTHLES-ACQFLEAFLDVVLAAEELRYAAVAVGKVTGIDVEDILDAVFRDFC Lenti61 TIYALSTPPG-KAGVAVIRVSGPDARGEIVHPEVLDDGL-AVFFKG-PRSFTTEDVLELHVHSGRAIISSVLNAISFFCRPAERGEFTRRAFGGRLDLTQVEGLRDLIDAETESQRKLALRTAG-GSTRARLEALRNETIQCLALVEALIDFGEG--EEIEEGVFEQADNRRGEIMRSGIRLAIFGPPNAGKSSLLNFLAQREAAIVTPIPGTTRDILELSLDIGGLPVIVADTAGLRKTDIVESIGVDRAKQLVSDISLCVLSTFILLNKTDF-VSLSTGTQDFMESFITHARHRAHMEN-ALDFLEAFLDVVFAAEELRYAAQAIGKISGIDVEDILDAVFRDFC Malgl1 -------------------------RRSIIHPELLDDAL-AVYFPH-GRSFTGQATLELHLHGSPAVVRDVLEALDAMMRPALPGEFTRRAFHGRLDLTACEALDSLLHAETSQQRRLAQWAAQ-GYQAQLYDRLYAQLVQAMSQMEAMLDFSDE--DDVNEHLWISVRRSYADAVMQGVRIALYGRPNAGKSSLLNRLVRRDAAIVTPYAGTTRDVLEVCMELAGYRVTLADTAGVRASDAVEQIGVERTQAYVADMCVLVCTVLILINKMDECASVLHGMDLLMNELVTQARHRHILMD-VVACLDTVLDLVVVAEELRHAAHLLAQVTGITSDTVLGEIFARFC Mellp23 NIFAAATPTNSKSALSIIRVDGPQALRRIVDPETLDPEAIVINFPHQSTSTTS--TFEFHLHGSPAITKSVILSLSRLFRLAQPGEFTQRRYQPEFDLNQLLALKNLIDAETDEQRKLAIHQFD-GPFKQVYQSMRKTLLESMALCEAIIDFSED--GSIDESVWKQVDSNRHEKVLNGIRLTLFGAPNVGKSTLLNWLVNREASIVSPHPGTTRDVIEISLDFHGFPIIVSDTAGLRDTDPIEEIGIDRAKSK--------------------------------------------------------------------------------------------- Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr TVYALSSAPG-KAGVAVVRISGPEAVARLSDPDLLDQAL-VLTFPG-PRSFTGEDVVELHLHGSRAVVAGVLDALGRLLAPAPPGEFTKRAFHGKLGLTQVEGLADLISAETTSQRQQALRHLE-GDAQKLLLGWRQELLHALALLEAYIDFSED--ENIEEDAFSSADSRAGQRVRDGVRIVLSGLPNVGKSSLLNYFCRQERAIVTDIPGTTRDLLTVDLELRGFPVIFVDTAGIRFGDRVEQEGVRRAQEAAADVRICLQDLLRVVNK----VSCLENLDQLTTVLVVRHRHQQHLTA-ALEALEQALDCVLMAEEMRYALSELGHLTGVKLDEMLDIVFSEFC Morel2 TIFALSTHPG-KAGIAVVRVSGPQATRRLLCPELLDKGM-VVWFPG-PRSFTGEDSVEFHCHGGKAVIDGILRGIGNTVRLAEPGEFSRRAFNNKLDLTEVEGLADLLNAETEAQRRLALRQAD-GGLKNLYETWRTQLIKSMALIEALIDFGED--ENIEDDVYDNVDDRCGEILRDGIHVTILGPPNAGKSSFLNIITKRQAAIVSPIPGTTRDVVEVSLDIGGYPILIGDTAGLRSSDEIEMEGVRRAQDRIADINIAILPTMVLINKMDL-ISCQTGIGQFLHDFITQYRHRKHLEN-CIQSLDAFLDIVLGAEELRHAASDLGRITGVDVEEVLDVVFREFC Mucci2 TIYALSSSPG-KAGVAVIRISGNNAFRRIRHPQVLDRGL-VLWFPG-PHSFTGEDSVELQIHGGNAVVKSVLDALHHIFRMAEQGEFSRRAFNDKLDLTELEGLADLLNAETEMQHRLALRQAE-GGLRKPYEHWREQIIKCMATTEAVIDFGED--ENIEDGVMDQVDSHVGEIVRNGIQVAIVGPPNAGKSTLLNRLAKREAAIVSNIPGTTRDVVEVKLDLGGYPVVVCDTAGLRESDLVEIEGIKRAKARIADIKICLLSTYLVLNKDDVYMSCSTGVDVFLKQMITQARHREHLEH-CVLHLEAFLDIVLSAEELRQAANALGRITGIDVENVLDVLFGQFC Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 TIYALSSGSG-RAGIAVIRISGPGCVRTLTEPNVLDTDALVLYFPG-PKTVTGEDVLELHVHGGPATVKAVLSAIPK-IRYAEQGEFTKRAFNNRLDLAQVEALGDTLSAETEQQRRAAIRGTS-GVLGKTYESWREQLLLARGEIEALIDFSED--QHFPTELLRNVGSQRSELLRNGIRIALLGPPNVGKSSLMNLIVGREASIVSSEAGTTRDIVEASLDIRGYLCSFADTAGIRTRGKIEEEGIRRARQKASDVIIVLAS-LLVINKSETVISCRTKIHHLISRLGVTARQNELLGQ-CRDALEDFMDIVLAAEHLRVAAGRLAAITGGDVEEVLGVIFEKFC Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 TIYALSTAIG-RAAIAVVRVSGPACLRTLYDPTILDAGALVLYFPS-PRTATGEDILELHIHGGPAITKAVLSAIAQ-VRYAEPGEFTRRAFNDRLSLPQIEALGDTLSADTEQQRRLAVRGSS-DALLNRYERWRQGLLYARGELEALIDFSED--QHFTEELVSSVNASRGELLRNGIRVALLGAPNAGKSSLLNRVVGKEAAIVSTEQGTTRDIVDVGVDLGGWYCKLGDMAGIRAEGPVEKEGIRRARERASDVVIVVVSLIVAINKCDKLISCEENLQVFLRGLGVTHRQSSNLQI-CLDHLDDFLDIVTAAEHLRFAADMLAKITGGDVEDVLGVVFEKFC Phybl2 TIYALSTSPG-KAGVAVLRISGSRAFRRIRDPEVLDRAL-VLWFPG-PRSFTGEDTVELQIHGGNAVVKSVLDALGSLFRMAEQGEFARRAFNDKLDLTELEGLADLLNAETEIQRKVALRQAE-GGLRIPYDSWREDIIRCMATTEAVIDFGED--EQIEEGVLDQVDSRVGEIVRSGINVAIVGPPNAGKSTLLNRLAKREAAIVSDIPGTTRDIVEVTLNLGGYPVIVSDTAGLRESDLVEIEGIKRAKAR--QVYICLLSTYVLLNKQDAAVSCKTGVDVFLNDIITQARHRHHLEE-CVQGLDAYLDIVLSAEELRQAANALGRITGVDVEDVLDVLFGQFC Picst3 TIYALSTKLG-RAAIGVIRVSGPESVRKLYSPILLDEAL-TLFFNS-PNTYTGEDLLELHLHGGTAIIKSVLAAIKELIRYAENGEFSLRAFNGRFDLTEIEGIRDMIDAETETQRIASLSSLT-GNTKELFLQWRVGILNNIALMTTLIDFGEDH--DLTAQLFDNVKVRSSETLLRGIRMVLLGPPNAGKSSLLNLLANEDAAIVSDIAGTTRDIIDVPLDINGYKVVIGDTAGIRDTDKIEIEGMKRAIAKSCDLILAVL-VLVVLNKEDLIVSCLTGINSLKSALIISSRAQDLLENDVLQGFEDFCDVVLATESLKQSVEGIGKITGIGVEEILGVVFSSFC Plicr1 TIYALSTPPG-KAGVAVVRVSGPDARCRVVHPEMLDDGL-AVFFRG-PKSFTTEDVVEMHIHSGRAIISSVLSALAQLVRPAEPGEFTRRAFGGRLDLTQVEGLRDLIDAETESQRRVALQTAG-GVNRARFEGLRSEIIKCLAMVEAIIDFGEG--EDIEEGVLDQADNRRGEILRSGIRLAIFGPPNAGKSSLLNFLAQREAAIVTPVPGTTRDILELTLDIGGLPVVVADTAGLRKTDVVESIGVQRATTAVADASLCVLSTFFLFNKSDLAASLTTGTAEFLNGFITHARHRVRLES-ALQFLSAFLDVVFAAEELRYAAQAVGKVSGIDVEDILDSVFRDFC Polpo TIYALSSGAV-KSGVAIIRVSGPQSLSNFYDPEQLDRGM-YVWFQG-PNSFTGEDVLELHIHGGRAVIHDMLEALSKVLRMAEPGEFTKRAFNGKMDLTEVEGLADLLDAQTNQQRKIALQQMQ-GSIGKLYTELRDQLIRASAYMEAYIDFGDD--AEIEPAVVEQSDGKRGEKLRDGATVTIIGPPNAGKSSLINLLANRRASIVSPIEGTTRDVVEVMLDIGGYPVILGDTAGIRESDVIEREGVSMARDRVSEITLCVFDTIFLFNKIDLLLSCSNGIKDLLSRILTRMRHKEHLIN-CVESLNNYLDVVIASEELRSAIRSIGSITYVNVDDLLDVIFKDFC Pucgr2 TIYGPATPVGLKAALAIIRIDGPQALRKLVCPKVIDPEALLLRFDH-PKHAAS--TIEFHLHGSPAVSKSLLSTLSQLLRLAQPGEFTRRRFHGSMDINKVLGLKHLIEAETEEQRRWAVSEFD-SKFDHTYQQMRKKLKQSMALCEAIIDFSED--GSMDREIWNQVQSKRREKISMGIKVSLYGSPNVGKSTLLNYLVNREAAIVSPYPGTTRDIIELSIDYHGFPIILSDTAGLRSSDPVEEIGINRAKENIADVRLLLVSTMILVTKTDLLISVFDGMSQFIKSFYLTNYQKIQLEK-ILSHIEGFIDLVILIEELRLVSGLLAKLSFISTDEILGEIFQSFC Punst1 TIYALSTPPG-KAGVAVIRISGPDARCRVVDPEVLDDGL-AVFFKG-PRSFTAEDTLELHIHSGRAVIKAVLGALATFLRPAEPGEFTRRAFSGRLDLTQVEGLRDLIDAETEGQRKLATRVAR-GDIRVGYERLRGDIIHCLAMVEALIDFGEG--EDIEDGVYEQADNRKGEIMRSGVRVVIFGPPNVGKSSFLNYLAQREAAIVTHIPGTTRDVLELSLDIGGLPVVVADTAGVRQTDAVESIGVDRAKDAAADATVCVLSTIFLLNKADTVCSVKTGMKTFMDGLITHARHRVHLES-ALQFLQGFLDVVLGAEELRYAAQAIGKISGIDVEHVLDAVFSEFC Rhior3 -------------------------FRRIRHPETLDRGL-VLWFPG-PHSFTGEDSVELQIHGGNAVIRGVLDALKEIFRMADQGEFAKRAFNDKLDLTELEGLADLLNAETEIQRKLAMQQAE-GGLRVPYENWRKEIIECMATTEAVIDFGED--ENIEDGVLDE-DSRVGEIVRSGVHVAIMGPPNAGKSTLLNKLTKREAAIVSNIPGTTRDIVEVKLDLGGFPVILCDTAGLRESDTIEMEGIKRAKNRISDIKICMLPTYVILNKEDTIV----------------------------------------------------------------------- Rhoto1 TIFAPATGKG-KSAISILRISGDDALRKIVHPEVLDEGV-VLFFPA-HSALTAQPTLELHLHGSPALMQLLLRLLPTLFRIAEPGEFTRLAFAGKMDLTEVEGIRDLVEADTEAQRKLAARQAS-GLMREAYDSMRAKAIEATALIEALIDFGED--EGISEGVYEQADGRRGEIIRSGIHLAIVGPPNAGKSSLLNWLAQREAAIVTAIPGTTRDVVELSLDFHGLPISVADTAGLRSTDQVEAIGIERAMEKAADIKLCVLSTLLLLNKVDSSVSVKEGLRELAEVMVTQERHRRHLEE-TLTHLKAFLDIVDAGEELRYAVLALGKITGVDVEEVLGEIFRGFC Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 TIYALSTPANQTSAIAIIRISGTHALRNIYSPILLDTSL-LLYFQA-PYSFTGEDVLELHVHGGKAVVNSILKAIGSLIRFALPGDFSRRAFNGKFDLTQLEGIKDLIDSETESQRRSALSSFN-GDNKILFENWRETIIENMAQLTAIIDFADDNSQEITDEIFHNVKVEKSTILQNGIKLVLLGAPNVGKSSLVNSLTNDDISIVSDIPGTTRDSIDAMINVNGYKVIICDTAGIREKDKIEMLGIDRAKKKSSDLCLFIVDIIIVVNKSDLVVSCKTGIESLISTLIVSKRVSEILKNDVLYGLEEFFDIVLATENLRYASDGIAKITGIGIEEILDSVFSKFC Salro TIFALSSGGV-RAGVAVIRVSGPQAVRKLFDPDMLDHAL-VLRFDE-GHSFTGEAIAEFQVHGGNAVVSSVLKALEGVLRHAEPGEFTRRSFNDRMDLTQVEGLSDLITAETEQQRKQALSYMT-GKASKVYQTWKSTLLRAVAQIEAYIDFSEE--ENIEEDVTA---------------------------------------------------------------------------RVDQAGVRRATEAAADLRVCVQDTLVILNKTDISLSCKTGLPAFLEALITRERHRQHVAT-CLQYLKEA-DIVSRAQMMRFALNELGLILGVHLEDILDELFAEFC Schco3 TIYALSTPPG-RGGIAVIRISGPDARCRVVHPEPIDDGL-AIYFRG-PKSFTTEDVVELHVHSGRAIVSSLLSAISALCRPAEAGEFTKRAFGGRLDLTQAEGLKDLIDAETEGQRRIALNAAR-GSNRALYEDLRNRAIHCLAQVEALIDFGEG--DDIEEGVLDQADGRRGEIVRAGVRLALFGPPNAGKSSLLNCLAQREAAIVTPVPGTTRDILELGLDLGGLPIRVSDTAGLRATDEVEAIGIERAKRAIADVALCILSTYFLFNKSDLATSLITGTSSFIDGFITHARHRVHLES-AARFVQAFLDVIMGAEELRYAAQAIGKISGIDVEDILDSVFNDFC Schpo1 TIYALSTPPG-TSAVAIVRISGPNALRTIKHPEVIDKAL-MLYFKK-PSSFTGEDVVELQLHGGTAVVDVTLEAIKQSIRYAKPGEFSERAFNGRADLTQLEGLIDVINAQTAEQLYSANKEAH-GSIYDICFRWRKKLIEYRAFLEASIDFSEE--HELDDIETIKLGGKCKEVLRKGINVAILGPSNAGKSSLINLLANRRISIVSPQSGTTRDAIEVLVDINGFPVLLSDTAGLRKGQEIEKIGIEIAKARASQLTLFVFPIHFLINKVDCVVSCKTGLIDFLQALGWNERQRQCLSS-CSSHLSLALDIVVAAEEVKLATEDIGRVTGVDMENVFSVIFSKFC Sorma TIYALSSGSG-RAGIA---------VRTLTEPNVLDTDALVLYFPG-PKTVTGEDILELHVHGGSATVKAVLSAIPKSIRYAEQGEFTKRAFNNRIDLAQVEALGDTLSAETEQQRRAAIRGTS-GVLGKTYESWREQLLLARGEIEALIDFSED--QHFPTELLRNVGSQRSELLRNGIRIALLGPPNVGKSSLMNLIVGREASIVSSEAGTTRDIVEASLDIRGYLCSFADTAGIRTRGKIEEEGIRRARQKASDVIIVLAS-LLAINKSETVISCRTKIHHLISRLGVTARQNELLGQ-CRDALEDFMDIVLAAEHLRVAAGKLAAITGGDVEEVLGVIFEKFC Sphar TVFALSSAPG-KSGVSIIRLSGPFALRKLLHPEVLDSAL-ILWFQG-PNSFTGEDVAELHVHGGRAVIAGVLAALSDLLSSAEPGDFSKRAFNGKLDATEIEGLADLINADTSAQKKLALRQMG-GEMRRVCDGLIERMTHSLAAVEAYIDFGED--DLIESEVFEQEIGKRGERTRDGVRVAIVGPPNAGKSSLLNALTRRAASIVSPIPGTTRDVVETLLDLDGFPVVLADTAGIRETDQIEAEGVRRSIQRICDIRVCVLDTILVVNKTDLMTSCRTDISQLLDSLITQNRHREALMQ-CVSALERFSDVAIAGEELRLAIRHLGRITGVSVEEVLDVLFADFC Spipu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 TIFASASGKG-RSAIQILRISGDDALRKVVHPEILDEGV-VLYFPR-ESSLTAQPTLELHLHGSPALMSLMLKLLPTLFRIAEPGEFTRLAFAGKMDLTEVEGIRDLVDADTESQRKLAARQAS-GQMRQSYDSMRATAIEGMALVEALIDFGED--EGISEGVFDQADGRRGEIIRSGIHLAIVGPPNAGKSSTLNWLAQREAAIVTAIPGTTRDVVELSLDFHGFPILIADTAGLRATDQVEAIGIERALAKAADIKLCILSTFILLNKTDTFISVKTGLKELARELVTHARHRRHLEE-CRDSLDAFLDLVDAGEELRYAVLALGKISGVDVEEVLGEIFAGFC Stehi1 TIYALSTPPG-KAGVAVIRISGPDARCHIVDSELLDDGL-VVFFRG-PKSFTTEDVLELHIHSGRAIISSILSSLSHILRPAQPGEFTRRAFGGRLDLTQVEGLKDLIDAETEVQRKTALGVAG-GSAKVVFDGLRKEIIKCLALVEALIDFGEG--EDIEDGVYLQADNRRGEILRSGIRLAIFGPPNAGKSSLLNFLAQREAAIVTHIPGTTRDVLELSLDIGGLPVIVADTAGMRKTDIVEAIGVKRAEETLSDISILVLSTFILLNKADLLVSLTSGTQEFMDGFSTHPRHKAHLED-ALRFLDAFLDVVLAAEELRYAADAVGKISGIGVEDVLDVVFRDFC Tapde11 TIYALSTVAG-KSAVAIIRITGPRSLRSLKHPEMLDRAL-CFFAAG-PRTFTGEDTCELHLHGSRAVINAVLEAIPDCTRHALPGEFSKRAFNGKMDLTQAEGLADLINAETDEQRKSAFRQAD-GSLTRIYDAWRTDLLKMRTTLEAVIDFGEDN-EDVEDIVASKVSSLKGELIRNGIRVTIFGPPNAGKSSLLNILAQKDASIVSYEAGTTRDIVESFMDIGGYPIIMSDTAGLRSGGHIEQEGIKRARRRIADIRLCVISIIIFLNKSDLDISCIKGIARMKSALGTNPRHRAQLRE-CLSHLGLFLE----------------------------------- Thetr -------------------------ATQLVHPQVLDSGM-AVFLTS-PRTATGEDMAELHVHGAPAVVAAVLDGL---MRMALPGEFTRRALAGKMDLVQVEGLADLLAASSEAQRATALAAAL-GNHSATYTAWTEAAAHALAMAEAMVDFGED--EGLDAAALDAAGARASMAIRDGARVALGGLPNAGKSSMLNVLAGRDAAIVDATPGTTRDALEVPLDLGGFPVVVADTAGVRAS--IEAEGIRRAQAAWAAIRVLVVDQLVVLNKAD-TISCADGIDALEAELVTRARVRDHLRT-AHDSLVRAF---LVGEALRDAVAALGSITGVDAEAVLDIVFAEFC Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 -----------------------------------------------------EDVLELHIHGGTATIKAVLAAIPQ-IRYAEPGEFTKRAFNDRLDLARVESLGDILSAETEQQRRAAVRGTS-GKLARTYEGWREELLLARGEIEALIDFSED--QHFPADLLHNVGGQRSELLRSGIRIALLGPPNVGKSSLMNLIVGREASIVSGEAGTTRDIVEASLDIGGYLCSFADTAGFRSSGAVEREGIRRARQKASDIVVVLAS-LIVVNKRDTVISCKEGIHALTEAMGVTARQAQLLAR-CRGHLEEFLDTVLAAEYLRYAADCLARITGGDVEDVLGVVFEK-- Umbra1 TIFALSTAPG-KAGVAVIRISGKNALKKIYHPELLDKGI-VLWFPG-PQSYTGEDTAEFHIHGGNAVTRSVLDALGSIYRIADRGEFSRRAFNDKLDLTELEGLADLLNAETEMQRKLALRQAE-GSLRQQYDGWREQLIKCMALTEAVIDFGED--ENIEDGVLNDVDNRIGEILRDGIHITISGPPNAGKSSFLNTLARREAAIVSDIPGTTRDVVEVSLNLGGYPVVLSDTAGLRESDLIEMEGVKRAMAKISDMHICLLPTILIINKSDASISCKTGIDQALESLITQARHRFNLSA-CLAALDMVADIVLAAEELRQAASAIGRITGVDVEQVLDMLFSEFC Ustma22 TIFALATGAG-RAGVAMIRISGPLTLRNLHHPELLDAGAGIIHFPA-GSSYTGEESLELHIHGGLATISGVLDALVVFMRIAEPGEFTRRAFNGRLDLASAEALHGLVLAETAVQRRVALQGTS-GLQTERFERIREVLLSAMAMVEALIDFSDE--GGVEEGTWKVAPRHIGEILSTGIHLALYGPPNAGKSSLLNRLADRNAAIVSDIPGTTRDVLQVHLDLAGYKVIVYDTAGMRDEDEIERIGIRRAKDAVADLALLVLPDLIFYNKSDLLGSVHTNIPNLISDLITQTRHRALLHQ-CLEHIHAFEDLVLAAEELRYAAKAVGKITGVTPDEILGSIFATFC Walse1 TIFALASAPG-KAGIAVVRVSGPDVNRRILHPEVIDNAL-LVYFKA-PRSFTSQDTLEMHLHGGNAVVSATLNALAEVCRPAERGEFTRRAFAHKLDLTELEGLRDLIEAETEMQRKLALRQSS-GAVREQYDDMRLEIIHCLSIVEAVIDFGED--EQIEEGVLDDADGRRGEILRSGIRLAIYGPPNAGKSTLLNHLAKREAAIVSPLPGTTRDVIELNLNLGGYPVIVSDTAGVRHTQEIEKLGVQKAIDVAADITLVVLDAIVLLNKADALGSVKTALENFIASLITDARHRYHLEE-CLGFLQAFVAPVEAAEELRYAALALGKVTGVDVEDVLDALFAGFC Zygro1 TIYALSTAPGTKSAIAVVRISGTHSLRNLYGPNLLDKAL-TLFFDS-PKSYTGEDLLELHIHGGKAVTGSVLNAIGSLIRYALPGEFTQRAFNGKIDLIEVEGIRELIDAETETQRRCALSSFN-GMNKNLFMLWRDKIVNNIAQLTAIIDFGEDT--EITNNLLQLVKIEKTSILQSGVKVVLLGPPNAGKSSLINSISNDDVSIISHTPGTTRDTVEASIDVNGYKVTISDTAGIRSHDEIELLGIERAIKKSCDLCLLIVDFVIIVNKQDLLVSCKTGIEPLVKQLIASRRVKEILHSDVLYGIDSFFDVVMASEHLSHAADGIGKITGVGIEEVLGVVFANFC [Cluster2798.fasta_al_trimmed; alignment length = 146] Allma1 MTTAARPTFNPAMGKELPGYKTLKRQT-GQN-SRNLK-SELQQAEREA-E-DPDADLDSDADDD-DDDDDEDETEALMRELEKIKRER-AEERERQE--EEEEALMAGNPLLNKKRWDDDVVF--KNQARRFINDTIRSDFHRKFL Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MTTAHRPTFDPAQGRLLPAYTHLKRQL-GQG-SRDLR-AELLQAEAAILE-EIDADSDSSEESD-D----EDEAAELMRELEKIKRER-LEQKEKEEREQREYDIARGNPLLNKRRWDDDVVF--KNQAREFVNDLLRSDFHKRFM Aurde31 MSTAHRPTWDPAQGRDMAQQTKLKRQP-GQT-SRDLR-SELLVAEAAVLQ-ELDKDDDDDDDDE-ESSDDEDDTAELLRELEKIKRER-AEEKARQEAADREIEIATANPLLNKRRWDDDLIF--KNQAVHFVNDLLRTEFHKKFM Batde5 MTSAARPTFLPAVGKEQTAHTKLKR-------SIDFK-RKLESSENELLE-QIDADDNQSSDSD------EDDTAELMRELAKIKRER-AEEAERQEREMMEDRAKTGNPLMAKRRWDDDVIF--KNQGKQFINDMLRSDFHRKFM Botbo1 MSTAHRPTWDPAQARDMAAQTKLKRQP-GQT-SKDLR-AELMLAEKEMLS-ELDRDDDDDDDDD-SDEDDEDDTAELLRELEKIKRER-AEEKARQENEAREAEIALGNPLLNKKRWDDDLIF--KNQAMQFVNDLLRTEFHRKFM Botci1 MTTAHRPTFDPAVGRLLPAHTQLKRKP-GQG-GRDLR-AELLQAEAAILE-EIDADSDSSDDDD-D----EDETAELQRELEKIKRER-AEKREQEEREEREHDIALGNPLLNKRRWDDDVIF--KNQAREFVNDLLRSDFHKKFM Caeel MTTAHRPTFHPARGKDMPSHTKMKRQT-GQE-TKDLR-RELEDKERNIAA-EVDADELNSSDDD----SDEDDTAALMAELEKIKKER-AEEKAARDEEQRMENILAGNPLLNKRRWDDDVVF--KNCAKTFINDAIRSEFHKKFM Canalb1 MSTNHRPQLESKRGRGLPQQTSIKRQD-IKN-EDDLQ-KH-------ITT-EIDKQSSESDEDD-ESSDDDDDTALLLKEIENIRREK-EKQNS--------DST--NNSINNKKSWRSSTTF--NNKSKNYTTDTLNSQHHQKFM Cangl -------------------------------------------------------------------------------------------------------------------------------------------------- Capow -MSGRSFDLNSAVGRDLASQTVLKRQA-GQG-NRDLK-GELELREQELVD--IDGRVMQSDETK------MTATREIHDELER------RQEEERIRNQ--------------KRGWDDDVVF--KNCAKRFINDSLRSDFHRKFM Catan2 MTTAARPTWNPAMGAS-------SSQR-GQN-SRNLK-AQLQQAEREPDD-DPDRDMDSNDEDD-DDSDDEDETEQLMRELEKIKRER-AEERERQEREEREEALLTSNPLLQKKRWDDDVVF--KNQARRFINDTIRSDFHRKFL Cioin MTTAHRATFAPAKARDLPSHKTLKRQP-GQN-ARDLR-HELAEREHSV----LDADDDSDSDDD----S-EDDTAELMAELNRIKKER-AEETAKLEEEIRTENILSGNPLL-KRRWDDDVVF--KNCARNFINDTLRSEFHKKFM CocheC53 MTTAHRPTFDPARGRLLPAHTTLKRQP-GQG-GRDLR-AELLEAEARLLE-KVDADDESSD-DD-D----EDGEGALQRELEKIRKER-AAAKAKEEAEQREIDVARGNPLLNKRRWDDDVVF--KNQAREFINDMLRSDFHKKFM Coere1 MTTAARPTFDPAKGKDLPGHTKLKRKP-GQG-GEELR-KELEEAERRLLD-ASDEDDEDNEKTD-SDEDSEDETALLLRELEKIKRER-AEERAREEQKSGGPSLVGGNPLL-KRRWDDDVVF--RNQARRFVNDMLRSDFHQKFM Conco1 MTTAARPTFDPARGRDLASETKLKRQP-GQT-TLDLK-EQLLQAERELE----DAADNLNSDDL-NDSDDDDENAELMRELEKIRQER-AIEKERQELEDNEERAILGNPLLFKRRWDEDVIF--KNQARRFINDLLRSDFHRKFM Conpu1 MSTAHRPTWDPAQARDMAAHTKLKRQP-GQT-SRDLR-AELLLAEEELLQ-EMDKDDDDDESDD-ED-DDEDETAELLRELEKIKRER-AEEKARQELESREAEIATANPLLNKKRWDDDLIF--KNQAMRFVNDLLRTEFHRKFM Copci MSTAHRPTWDPAQARDMAAHTKLKRQV-GQT-SRDLR-AELLAAERELLQ-ELDKDDSSEEEDD-DDDDDEDETDELLRELEKIKRER-AEEKARQEREQKEADIATRNPLLNKRRWDDDLIF--KNQAMEFVNDLLRTEFH-KYV Croqu1 MSSAHRPTWTPAMGRDIAGHTKLKRQP-GQN-SRDLK-LELELAERDILE-EADKDDDDSDDDD-DDDDDENETAELLKELEKIKRER-AEEKARQEQEDKEASAAMGNPLLNKKRWDDDVIF--KNQAREFVNDLLRTEFHRRFL CryneH991 MSQAHRPTWNPAQGLSLAAHTKLKRQP-GQT-NRDLK-AELLAAERAILE-EMDKDDEDDDDSD-DESDDEDDTAALMAELAKIKQER-AEEKARLDAESREAEIATGNPLMNKRRWDDDLIF--KNQAVEFVNDLLRSEFHKKFM Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 MTTNHRPTLESKRGRSLPQHTSLKRGD-IRK-PEELK-KDLLLNEGK-------MDEQEYDEED-DSGD-EDETAQLMEELAKIKKER-QEEQEKLELQ-KLDKTKVSNPLVQKKSWRDSTAFKKQNSQNTFTNDTLNSEFHQNFL Dekbr2 MTTAHRPTFDQARARALPGYKTLKRKK-AKKVNKSLR-ETLLLEEKRLKQ-E-EGDDDESSSDD----DEEEEEEELLRELENIRKEK--ETKAKDEHEVRE-------PIPDRKSWRSQSLF--HLQKRPMINNMMQNDFHKRFM Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------- Dmel MTTAARPTFDPARGRDLPGHTKLKRET-GQG-TRDFR-KELEEREREAAQ-QMDADEDSSDSSD----SDDDD-AALLAELQKIKQER-LQETARRESEIRMENILSGNPLMNKRRWDDDVVF--KNCAR-FVNDALRSDFHKKFM Enthi MTNVGRPTWYSARGQDVIVQPELKRKV-HQLITEELKPKKIEYKESNIKE-E----------ES------EDTEEALKKEYEEMEEEE-EFSNSSDSQQ--------------QRKWYDDVVF--KNQAKKYINDTLRNEYHQHFM Falba MTTSHRPTFHPAIAVAPGANTTVSKD--GNL--RD-S-GDAPAVPATLSDGDLDADVADDDDDD-DDDDDDDDEAALQRELEAIRRERAAAAQARADQEELDREALTANPLLQKKKWYEDTIF--KNCTRSYVNDILRSDFHRKFM Fomme1 MSTAHRPTWDPAQARDIASHTKLKRQP-GQT-AHDLR-AELLEAERALLQ-ELDKDDGSDEDDD-DESEEEDETAELLRELERIKRER-AEEKERLEREAREEEIATANPLLNKRRWDDDLIF--KNQATQFVNDLLRTEFHKKFI Fusgr1 MTTAHRPTFDPARGRLLPAHTQLKRQA-GQG-GRDLA-AELLAAEATILA-EIDADDEDSD-DD-DDSD-DDSDAELQRELDRVRRER-EERKKKEEAEARERNIALGNPLLNKRRWDDDVVF--KNQAREFVNDLLRSDFHRRFM Galma1 MSTAHRPTWDPAQARDMAAHTKLKRQV-GQT-SRDLR-AELLAAEQDLLQ-ELDKDDDEDESED-SD-EEEDDTAELLRELEKIKRER-AEEKARVEQESREAEIAAGNPLLNKKRWDDDLIF--KNQAMNFVNDLLRTEFH-KFV Ganpr1 MTSAARPTWNPAVGRDLPGNTTLKRQP-GQN-ARDLR-AEL-----------IDADDDADADSD-SDSDSDDDASALLRELAKIKSER-AAARAQSELAESLARAAQGNPLLTKRRWDGDVVF--RNQAKRFVNDMLRSDFHRKFM Gloin1 MTTAARPTFDPARGRDLAAHTKLKRQT-GQL-TIDLK-EELLKAERELLI-E-DKDD--EEDDS-EDLDEEDDALALQHELEKIRKER-AEEKERQELEKKQEEALTGNPLLNKRRWDDDVIF--KNQARRFINDTLRSDFHRKFM Hisca1 MTTAHRPTFDPARGRLLPAHTFLKRQP-GQG-GRDLR-AELLKAEAAILE-EIDADSDTSEDDD-D----EDETAELMRELEKIKRER-AEQKAKEEQEKREVDIARGNPLLNKRRWDDDVVF--KIQA----------------- Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MSTAHRPTWDPAQARDMAAHTKLKRQV-GQT-SRDLR-AELLAAEHELLQ-ELDKDD-DDESED-SD-DEEDDTAELLRELEKIKRER-EEERLRLENEKREADIATSNPLLNKRRWDDDLIF--KNQAMHFVNDLLRTEFHKKFM Lenti61 MSTAHRPTWDPAQARDTPAHTKLKRQP-GQT-SRDLR-AELLVAEAELLE-ELDKDDDEDEDDD-ED-DEEDDTAELLRELEKVKRER-AEEKERQEREEREAEIATANPLLNKRRWDDDLIF--KNQAMHFVNDLLRTEFHKKFM Malgl1 MSSAHRPTWEPARAHAAPTQTRLKRKP-GDT-QQELK-DQLIAGEKRLVS-WADDDEDEQDEDDEEDEDEEDDTEALLRELEKVKQER-REQQARLEQTTREEEIARGNPLLNQARWDDDLIF--RNQASGFVNDLTRTSNAMLTL Mellp23 MSSAHRPTWTPAMGRDIAGHTKLKRQP-GQN-SRDLK-LELILAEKEILE-EADKDDDDDDESD-DSDDDENETAELLKELEKIKRER-AEEKERLEQEDKETSAAMGNPLLNKKRWDDDVIF--KNQAREFVNDLLRTEFHRRFL Mnele MTTAARPTFEPARGRDLPGHTKLKRQL-GQD-TKDFK-RDLDEKE--L----LDQDEDSSSDSS----SDEDDTSELLAELARIKRER-ANDRQKQEVEIRKETILSGNPLLKKRRWDDDVVF--KNCAKRFINDTLRSEFHKKFM Monbr MTTAHRPTWTPAQGRDVVAHTKLKREE-GQG-TKDFR-SELEDREREITH-ILDADDDDADSSDESDSDDDDDTELLLAELEKIKRER-ADEQARKDTE-RRESALQGNPLLRKRRWDDDVVF--KNCAKTFVNDTLRSEYHRKFM Morel2 MTTAARPTFDPARGRDLASHTKLKRQT-GQT-TVDLK-AQLKKAEQDLLQ-ELDKDDSDDSDDD-SDSDEEDDTAELLRELEKIKRER-AEEKERQERIAREAQVAAGNPLLDKRRWDEDVIF--KNQARRFINDTLRSDFHRKFM Mucci2 -------------------------------------------------------------------------------------------------------------------------------------------------- Mydma MTTAARPTFDPARGRDLPSHTKLKRQT-GQD-TRDFK-RDLTDRERAI----LDADDDDEEGDD----SDEDDTAELLAELQRIKRDR-AEELMKKEQEIRTENLLTGNPLLQKRRWDDDVVF--KNCAKGFINDTLRSEFHKRFM Neucr2 MTTAHRPTFDPAKGRLLPAYTQLKRKP-GQG-GRDLR-AELLAAEEAILE-LIDADDDDADADD-DDASSDDEEAELQRELERVRRER-QEKREREELEQREKDIALGNPLLNKRRWDDDVVF--KNQAREFVNDLLRSDFHRRFM Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MTTAHRPTFDPAQGRLLPAHTHLKRQP-GQG-GRDLR-AELLQAEAAILE-EIDADSDSSDESD-D-----DEAAELMRELEKIKKER-LEQKEKEEREQREVDIARGNPLLNKRRWDDDVVF--KNQAREFVNDLLRSDFHKRFM Phybl2 -------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 MTTNHRPTLESKRGRALPQQTTLKRED---G-SEELK-TELLIREGRKET-EIGIDDNEGDDED-SESDDEDETELLLAELAKIRQER-QEEKERVEEQ-KIDRALLSNPLVSKKSWRLTTTF--SNRPNTYTNDTLRSKHHQNFL Plicr1 MSTAHRPTWDPAQARDMAAHTKLKRQP-GQT-ARDLR-AELLAAEQEMLQ-QLDKDDDEDESED-SD-DEEDDTAELLRELEKIKRER-AEEKARQEREERDAEIATANPLLNKRRWDDDLIF--KNQAMGFVNDLLRTEFHKKFM Polpo MSDKY---------KDLAGHTKMKRDDVGQK-AIELKQKQMLDSRKELEQ-RIDADDDNDDSSD-SDDDDEDDEEELMRELEKLKREK-AEAQKRKQMEARQEKLISSNPLLNKKKWYDDSIF--KNQARRFINDTTRNDFARKFL Pucgr2 MSSAHRPTWTPAMGRDIAAHTKLKRQP-GQN-SRDLK-LELEMAEREILE-EADKDDDDDDDDD-DSDDDESETAELLRELEKIKRER-AEEKERQEREDKEAEAAVGNPLLNKRRWDDDVIF--KNQAREFVNDLLRTEFHRRFL Punst1 MSTAHRPTWDPAQARDMASHTKLKRQP-GQT-SRDLR-AELLAAEAELLQ-EMDKDDDDNDDDD-DD-EEEDDTAELLRELEKIKRER-AAEKARQEAEEREAEIATANPLLNKRRWDDDLIF--KNQAVHFVNDLLRTEFHKKFM Rhior3 MTTAARPTSDPAEGRDLASHTKLKRQP-GQG-TEELL-EELRNAERKLLA-ELDKEDEESSDDE-DDDDDDDNAAELLATLQRIRKER-AEEKERQEREKKQQEAMEGNPLLNKRRWDDDVVF--KNQARRFINDMLRSDFHKKFL Rhoto1 MSSAHRPTWAPAQGRDIAAHTKLKRQP-GQG-TRDLK-AELLAAERELLQ-ELDKDDDDDDDDS-SDDDDEDETAELLRELEKIKKER-AEEKERQERESRDEEIATGNPLLNKRRWDDDVIF--KNQAREFLNDLGRSQYHKAFM Rozal11 MTTAHKPTWTNALGRDMAAHTKLKRQP-GQN-TRDLK-ALLLNEKPDISP-ELDKDDESSDDSD-FSAEEEDDTAELLKELEKIKEER-KKEQGKLALEEKSNRAMIGNPLLNKKKWYDDVIF--KNQARRFINDLIRSDFHRKFM Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------- Salro MTTAHRPTWTPAQGRDAPAHTKLKRHD-VE--TK----RELEQREAKITT-D-DLPEDESDSSD-SD-DDDDDTAQLLAELEKIKKER-AAEQARK--EVRLASIVKGNPLLNKRRWDEDTVF--KNCARRYINDTLRSESHMKFM Schco3 MSTAHRPTWDPAQARDMASHTKLKRQA-GQT-SRDLR-AELFAAELELLQ-EADKDSEDEEDSD-ED-EDEDDTDELLRELEKIKRER-AEEKARQEREAREAEIATANPLLNKRRWDDDLIF--KNQAMGFVNDLLRTEFHKKFM Schpo1 MTTAHRPQFDPARGRALPAHLKLKRQE-SQG-TQDLR-EALLRAEAALLR-QADEDANSQESSD-EESDSEDETQQLLRELENIKQER-KREQMLQEEKKREREIAFGNELLNKRRWDEDVVF--RNTHKGFVNDMLRSEFHKKFL Sorma MTTAHRPTFDPAKGRLLPAYTQLKRKP-GQG-GQDLR-AELLAAEEAILE-LIDADDNDSDADD-DDNDDDDEEAELQRELERVRRER-QEKREREEAEQREKDIALGNPLLNKRRWDDDVVF--KNQAREFVNDLLRSDFHRRFM Sphar MTTAHRPTWTPAIGRDLPSELTLKRKR-APGDELDLK-EDLLRKERELVD-DLDADDDEDDSDD----DSDDDEAELLRELENIKRER-AEEQAEKDAEIRTESLMQGNPLLHKKRWDDDVIF--KNCARTYINDTIRSEFHRRFM Spipu1 MTTAARPTWNPAAGRDLATQTKLKRQP-GQN-AQLLK-ERLEQKEREMRV-EIDADDGAESEDS-DDNDDDDE-AELLRELEKIRRER-AEEKERLEQEKREEEALTGNPLLQKRRWDDDVVF--KNQAKRFINDVLRSDFHRKFM Sporo1 MSSAHRPTWAPAQGRDLSAHTKLKRQP-GQD-SRDLK-LELLQAERELLQ-ELDKDDQEEDDDD-SDDDDEDETAELLRELEKIKRER-AEEKERQERESREEEIALGNPLLNKRRWDDDVIF--KNQAREFVNDLLRTV------ Stehi1 MSTAHRPTWDPAQARDMAAHTKLKRQA-GQT-SRDLR-TELLEAEMELLQ-QMDKDEDSDESSD-EDSDEEDDTAELLRELEKIKRER-AEEKERLEREERDAEIATSNPLLNKRRWDDDLIF--KNQAIEFVNDLLRTEFHKKFM Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------- Thetr YTKIGARNVRATVSAELPGHTQLKRR--GQV--EELA-AELAAREAAL---QVDADVLDSDSSD-SDSDSDSDMEQLMAELNKVR----AEAKERAAREERKAELLAAASNVGGRSFMDDTVF--RNQATGFVNDTIRNEFHRKFL Treme1 MSQAHRPTWNPTQGHALAAYTKLKRQP-GQT-SRDLR-ADLLAAERLVLE-QLDKDDEDDDSSD---SDDEDETAALMAELESIKRER-AAEKARQEAESREAEIATGNPLLNKRRWDDDVIF--KNQAAEFVNDLLRSEFHKKFM Trire2 MTTAHRPTFDPARGRLLPAHTQLKRKA-GQG-GRDLA-AELLAAEAAILE-EIDADDEDSD-DD-DDSE-DDEDAELQRELERVRRER-EEKKKREEEEARERDIALGNPLLNKRRWDDDVVF--KNQAREFVNDMLRSDFHRRFM Umbra1 MTTAARPTFDPAKGRDLPAHTKLKRQP-GQG-TDLLK-EELRRGERELLA-ELDKDDDSSDEDD-DDDDDDDNTAELLAELEKIKKER-AEEKERQERQAKEEQAMTGNPLLDKRRWDDDVIF--KNQARRFINDTLRSDFHRRFL Ustma22 MSTTHRPTFTAAKGLSIPQHTKLKRRP-ALS-SRDLK-RELEHAEWSAIE-QLDRSSSSSESDD-ESSDSSDEQHALLLELQKIKSER-AAQHAALHRQSRDHELAHANPLLNHNRWDHDVIF--KNQATSFINDLTRSDFHKKFM Walse1 MSTAHRPTWDPAVGRDAPSHNKLKRKP-GQG-GRDLR-LELTKAEEELLE--VDKDEDNDEEDE-SDEDSEDDEAELLRELEKIKRER-AEEKARKDEESREEEIASGNPLLNKRRWDDDLIF--KNQALEFVNDLVRTDFHRKFM Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2830.fasta_al_trimmed; alignment length = 68] Allma1 SQLEHLQSKHVGTGHADTTRYEWLVNQHRDTLAAMVGHTHLTAFMALAEHER-VRYNLKSKMI--APC Ashgo11 RLFQAMKQKHIGLGTDDTSRDEWLTQVHRDTYNSLLGHSALLQYAALSGPTAETRLAMVSRMC-GGPA Aspfu1 QNLEALQARHVGTGHADTTKYEWESNIIRDSYASYIGHPPLLSYMALGMGEK-VRAAMIEKMV--RGA Aurde31 AQLEHLHARYTGTGHADMTKYDWITHQHRDTCASIVGHAPLTSYLAIADGER-VKFEMTERML--QPC Batde5 NQLEHLQARYVGTGHADTNKFEWVQNQHRDTYASYLGHRTLMNYFAVAENER-LQTRFLSNIL--QPC Botbo1 TQTEHLHARYTGTGHADVTKYDWLTHQHRDTCASIVGHPPLASYLAIADGER-VKFEMMERML--QPC Botci1 QQLEQLQQRYVGTGHADTTRFEWTSNIQRDSYASYVGHPPLLSYMAIGMGSI-VRKNMIEKMI--QPV Caeel -------------------------------------------------------------------- Canalb1 NQYHLLKSKYPGVGDPDTTREEFLTTIHNDTVGALAHHHHLLLYNSLITNEQ-LKQKFIRKLK----- Cangl ------------MSQSSTSTEEWLLKVRRDTISSMIQHSGLNEYIMLAKGDRTTQIDLIEKYCNSFPA Capow SQLEHLQSKHVGTGHGDISKFEWLSNQHRDSAASYVGHPNMLAYFAVVENER-VRVNLLKKML--QPC Catan2 TQLEHLQSKHVGTGHADTTRYEWLVNQHRDTLALMIGSRHLTAQMALAEGER-AKYMLK------QVC Cioin SQMEHLQSKYVGTGHSDTTKWEWLTNQHRDTLASFVGHHDLLNYIAIAENER-VRFNMLEKMF--QPC CocheC53 QQLEALQARYIGIGSADTTKHEWTSNIARDSLSSYVGHPPLLQYMSIGLGQK-TRLQLLERMV--RPV Coere1 NQTEQLYARYEGTGNADTTRYEWLTNQHRDTLAHYVMDDSLAMFISIAEGER-TKFKMLERMQ--QPC Conco1 -------------------------------------------------------------------- Conpu1 TQLEHLHARYTGTGHADLTKYEWLTHQHRDTLSSIVGHPTLLSYLAVADGQR-MKFEMAERML--QPC Copci TQLEHLHARYTGTGHADLSKYEWLTHQHRDTLASIVGHPTLTSYLAIAEGER-IKFEMTERML--QPC Croqu1 TQLEQLHARYVGTGHADLTKHEWLTHQHRDTYASIIGHPALWSYLAIAEGER-IKFEVCERML--QPC CryneH991 TQLEQLHARYTGTGHADTTKYEWLTHQHRDTLASIVGHPPLLAYLSVADGER-ERFEVTEKML--QPC Crypa2 QELERLQAKYIGTGHPDTTSWEWKTNIHRDTKTSIVGHTPLLAYMSLAQNEK-ARAQLIRQMV--QPV Debha1 NQYNQLKSKYIGLGNADITREEFMTNVNRDIYSSLAQHDNILYYNSVIINEL-LRQKMIKKMA--SPI Dekbr2 KMYETMKAKFVGLGDDNTQRKEFIHNIKVDTYTALATNSSLVELLSVGLSRL-VRQDLIDKIA--KS- Dicdi SQLEHLQMRYVGTGHADISKHEWLTNQHRDSLSSFIGHSSFLSLFSIAENER-VRYNTLTKMI--SPC Dmel SQLEHLQSKYIGTGHADTTKFEWLTNQHRDSLASYMGHYDILNYFAIAENER-VRFNLMERML--QPC Enthi TQLEHMQLKYVGTGHPDISKYEWICNQQRDSYASYIGHHSLMAYIAVAENQR-TRYQFLERMC--DPC Falba --MAPLSSDF---------NSEWLLTQHRDTLASMVGHPQLLHFTALVDGER-TRVALIERMV--QPC Fomme1 TQLEHLHARYTGTGHADMTKYEWLTHQHRDTCASIVGHPTLASYLAIADGER-VKFEMTERML--QPC Fusgr1 QELERLQAKYIGTGHPDTTSWEFRTNIQRDTYSSIAGHRPLLSYIALAENEK-IRAQMIRKMV--QPC Galma1 TQLEHLHARYTGTGHADLSKYEWLAHQHRDTLSSIVGHPTLASFLAIADGER-VKFEMTERML--QPC Ganpr1 SQLEHLQSKYIGTGHADTNKFEWVVNQHRDSYASYVGHHNLVSYFAVAENER-MKFNFVEKMI--QPC Gloin1 SQLEHLQSKYVGTGHADTNKFEWMVNQHRDSYASYIGHHSLISYFAVAQNER-VKFEFVEKML--QPC Hisca1 QNLEALQARYVGTGHADTTKYEWTSNILRDSYASYIGHPPLLEYMAIGMGEK-VRAMMIEKMV--RGA Klula1 LIYEDMRKKHPGVGSARTTKEEWSNTISKDTYASLAIHQNLLEYYTLASGFRDAQLTLLRKLA--NP- Lacbi2 TQLEHLHARYTGTGHADLSKYDWLTHQHRDTLASIVGHPTLSSFLAIADSER-VKFEMTERML--QPC Lenti61 -------------------------------------------------------------------- Malgl1 PQLEHLHARYTGTIHPDTTKHEWATHQHRDTAAAIVANGALLTYNSIADGER-TKFRVCERMI--QPC Mellp23 -------------------------------------------------------------------- Mnele SQLEHLQSKYIGTGHSDTTKFEWLVNQHRDSFASYIGHYPLMDYFALAENER-VTFNLLEKML--QPC Monbr -------------------------------------------------------------------- Morel2 SQLEHLQSKYVGTGHADTSKYEWGVNQARDTYASYVGHYPMMSYFALAENER-VKFNITEKMV--QPC Mucci2 SQIEHLQSKYVGTGHADTVKYEWATNQYRDSLASFAGHNSMLSYISVAQNER-VKLNLLEKML--QPC Mydma -------------------------------------------------------------------- Neucr2 QELERLQAKYIGTGHPDTTSWEWKTNIHRDTYSSIVGHPPLLSYIALAENEK-VRARLIRKML--QPM Orpsp11 -------------------------------------------------------------------- Pench1 QNLEALQARYIGTGHADTTKYEWTSNILRDSYSSYVGHPPLLSYMAVGMGEK-VRTMMLEKMV--RGA Phybl2 SQIEHLQSKYVGTGHADTIKHEWLTNQQRDSYASYVGHNSLLSFFSVAENER-VKMNIMEKMV--RPC Picst3 -------------------------------------------------------------------- Plicr1 TQLEHLHARYTGTGHADLTKYDWLTHQHRDTLSSIVGHPTLTSYLAIADGER-VKFEMTERML--QPC Polpo SQLEHLQMRYVGTGHSDISKYEFLTNQHRDTYSSYVGHNSLLSLFAIAENER-VRFNLLHKMI--QPC Pucgr2 -------------------------------------------------------------------- Punst1 TQLEHLHARYTGTGHADLTKWEWLTHQHRDTLSSIVGHPTLLSYLAIADGER-VKFEMTERML--QPC Rhior3 SQIEHLQSKYVGTGHADTIKHEWLTNQQRDSLASIVGHNSLISYISVAENER-VKANMLEKML--QPC Rhoto1 AQIAQLHARYTGTGHADITKYEWITNQHRDTSSSIVGHPALLQYLAIADGER-TKFELTERML--HPC Rozal11 QVPRHWKYRY----HQIVTNSEWLNTQHRDSLASFVSHQNLLRYFSIAENER-TRLNLLDKMI--QPC Sacce1 KLQKIYKQKYIGLGDESTTREQWQRNVRNDTLNTLQGHSASLEYVSLSRGDRDTRIHLLKSM---SPG Salro SQQEHLQSKYMGTGHADTTKHEWVTNQHRDTYTSMIGHEGLMDYVSIAENER-TRFNLLQRMI--SPC Schco3 TQLEHLHARYTGTGHADISKYEWLTHQHRDTLASIVGHPPLTSYLAIADGER-IKFEMTERML--QPC Schpo1 AKLEQLQARYVGVGNAFTTKYEWMVNQHRDTLSSVVGHPPLLAYMATALGEQ-VRKNLLEKMI--MPC Sorma QELERLQAKYIGTGHPDTTSWEWKTNIHRDTYSSIVGHPPLLSYMALAENEK-VRARLIRKML--QPM Sphar -------------------------------------------------------------------- Spipu1 AQLEHLQSKHVGTGHADTNKFEWAVNQHRDTYASVIGHNTLIAYSAVAENER-KKFEMIEKML--QPC Sporo1 TQIAQLHARYTGTGHADSTKYEWMTNQHRDTSSSIVGHPALLQYMAIADGER-VKFELTERML--QPC Stehi1 TQLEHLHARYTGTGHADLSKYDWLTHQHRDTLASIVGHPTLASYLAIADGER-VKFEMTERML--QPC Tapde11 -------------------------------------------------------------------- Thetr -------------------------------------------------------------------- Treme1 TQLEQLHARYTGTGHADTTKYEWLTHQHRDTLSSIVGHPSLLAYVAIADGER-ERFELIERML--QPC Trire2 QELERLQAKYVGTGHPDTSSWEWRTNIQRDTYSSIVGHRPLLTYISLAENEK-MRAQLIRKMI--QPC Umbra1 SQLEHLQSKYVGTGHADTIKHEWLVNQHRDTNAAFVGHQSMLSYFAVAENER-VKFNLIQKMV--QPC Ustma22 SQLEHLHSRYTGTINADTEKYEWLTHQLRDTSSSIVGHPPLLSYNALADGER-VKFELTEKML--QPC Walse1 QQLERLHARYTGTGHPDISKHEWVTNQQRDTLSSIVGHPTLSSYMSIADGQR-TKFNMIEAMI--SPA Zygro1 R-YQVLKHKYVGLGREHTTQEEWLSNVHRDTYHSLQAHSGLLEYLALAQGSRQTKIQLIKKM----DQ [Cluster2839.fasta_al_trimmed; alignment length = 199] Allma1 -------------------------------------------------------------------------------------------MVISTPESFTVAT---------KGLMPNVKKGTV-T--TELAIDVLKNSRYTSGRTGDV-RVTVGKVGFTPEQVEKNLKFVLDEVKRNK----VHKIWMNATSPALPL Ashgo11 SSKLSKDQKKREL-RMPVQQALRFLRAAEVGQPTISVNTVIGDKALLSGTVTLPSPMR-ETKVAVFTN-DPEQAETARLVGGAEL--VEQDKAFATPDIAPLMAAKLGRVLGPKGLLPSAKKGTV-A--GDLSLGDDINSPFK-QRNNCI-SLAIGKCHFSDRQIMENLLAVQAAFKKTS----FGTTTLTSTGPGIVI Aspfu1 AK---AKSKEKKGPRFSLCDAIRYLRAFEVGREKYEIHILKTKRPVIRNMLRFPHSVQTESRICVVCPPGTRHEKEARLVGEQDV--FDADRLICHPDSLDALNAGLGRILGPRGLMPSIKTGTV-V--EDVAVEMLRGGVYR-ERDAVI-RLPIGQLAFSPEQLRDNLRATIEQV-----DRIIYEVVLSSTGPGFSL Aurde31 KKAAKAQAKKKRSSKLPLEEALAVLRAVEITRPMFELTITELDRTVPKGRISLPREPKEKDTIMVFAD--GKKAEDARFVGGTEM--IDENVILCTPDLIRAITPRLGRFLGPKGLMPSPRRGTV-T--DDIRISRTQGSEWKADKDGTI-RAPIGRVDYPTQDLVKNFRAYITAVSGKD-KIKVVKVILSSSGPGIV- Batde5 --SLIEARDKVKYRRITFDHAFSVFQTYTLGQ---DLPIIKIAHKPIRGEVMFPHQVGQKPVVLMFAT--GKQAEEAKIVGGDEL--IEQDRCLSTSEMFPKVI-KIARKLGPKGLMPSPAKGTV-S--DDLPMASLHASKFELGSNNMI-QVEVGRALWKESEVEANIKSLIGSI-----QDVVESISISAPTAGMKL Botbo1 ---------------MTISDAAAVLRAVEVATPAYELHVTRFVKPAPRGRISLPRDPRTEEKVLVFAE--GKQAEAATFVGGGEL--IDDTKVICTPALLPTITPKLSRFLGPKGLMPAVRRGTV-T--DDVAIKQARGMEWKGDRQGVV-RTPIGRINFPVEDLEKNIRTFLQAVAASS----ILQVHLSSTGPGIQ- Botci1 RK---TTEKKKKPRTFTLCEAMRYLRAFEVGRPKYEIHLMKSLKPVVRNRLRLPHPVKTDLRICVICPPDSKYAESAKLVGEEEI--FEADRCICQTDSLAKMNAGLGRVLGPRGLMPSAKTGTV-V--KDPSLKDLIGGEYR-ERLGVV-RMAVGQLGFTPEEMQRNVKAFIEAV-----DKIMVEVVLSSTGPGFIL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 KTHLQKEKKKRKLRQMPIAKALNILRSLEVGKPTISCNIVRQEQAPISGKVDIPFPVQRKTKPVVFTT-QQPVIEELKTFGGREL--LDKTHAFATQEMAPHLK-SVARILGRAGLQPTAKKGTI-T--DDVNILDVMRSQIK-QKENHI-SFPVGNCTFSDSQIMSNLKAISDEI--------LGYCYIGTASPGLVI Cangl APTLTKEQKKREM-KMPIPLALRYLRSAEVGRPTITVTTVVADKAALAGNILFPHPLK-QMKIAIFSS-NKEKLDELKIAGGEDM--IADNKVFATPEIFPTIASQLGRVLGPKGLMPNLKKNTV-G--EDLDIEENLGQSFR-QRGNSL-SVSVGRCNFSDRDILENIIAVRNAFKKPS----LGKTTISTTGPGIVI Capow SSSSSASAQAERNKKGSVTEAIQAIKAFAVRPQAMTLGIMRDAKHPVHAMVALPYVQKKREIILVFAR--GDDAAIAKVVGGPEL--FADDKVLATTDMLAEVK-AVAKYL--RQATPTVKKGTV-ADGEALGVQSMGTADMRSDRKGFI-NVKIGKTNQPAEHLFENIRAVLKAT--------IGWVALGGSLPTFPI Catan2 --------------------------------------------PPIRGTLILPCAVPKNVRILCFAD--GPAAQEAKIVGTTEL--VDQDMVISTPEAFPVVT-RVAKILGPKGLMPNAKKGTV-T--SDIQIDVLKNSRYTSGRGGDV-NVIVGRIGYSPEQVEKNLRFVLNEVKKNK----VHKVWVGATAPALPL Cioin KQGLVRNDKERQKPHKGVYETVKLLKKYTVLDYSVVLLQVGKGKLSFFDTADLPHPTNIRNKVCLFTD-IEEQVELALAAGGNEL--IYKDAYLSTQVFSENVIDKLGR------MKPSKKWGTS----DDFVLRALVTKIYQNYSNGLICKLKVGRLNQTAEELTANIEFMIRHI--------VEKASISCF------ CocheC53 TK---AQPKKKKTRNFSLIDAMQYIRAFEVGRNKYEMHVLRTLKPVVRNRLRLPHPVKTDIRICVIAPPDSKAAAEARLVGEDEI--FNQDRCICHIDSLQKMNAGLGRVLGPKGLMPSTKTGTV-V--TQVGVRNMVGGEYR-ERLGVV-RMAIGQLGFTPDEMQRNIKAFMEAL-----DRIIHEVVLSSTAPGFTL Coere1 -RSFVLN-RSKRD--VSLERAIAILKAYEVGQPTVEIHVCVPEKLPIRGSCILPLPIKSEVKLLVFAE--DEKADAAEYVGGEEL--VNSDKCLSTPEMLPKVA-KIARLLGPRGLMPTINKGTVIS--GDIAIKFAKNSDFKADKFNIV-HTGVAKTGFSVEEIIKNISAVMYAINAQA-SPKVRRVYISSTGPGVH- Conco1 NNTFIRSATKKNVIKIELETAARMLKAVSIGKESVELIVTNFNR-VLLGSTLLPKPVAQETKLLVFAE--GKHAEAAKIVGGPEL--VLQDRVITTTAMLKHVA-KIARILGPLGLMPTVKKGNV-T--DDVVINETNAQDFKSDNHGVV-KAPIGKVNFTEQELVDNALAIVKTI--------VEKVYVKSSSPAIL- Conpu1 KKAAAAKAARKKAAKMPLESAVHVLRSVEVARPTFELVVTAMGKTIPKGRISLPREAKTEDRILVFAE--GRQADEARIVGGPEL--IDATTILCTTGLIRTITPRLGRILGPRGLMPSERRGTV-T--DDIEIRRLQGTEWKGDKSGTI-RMPIAKVRRPFP------------------SSVLLLILIQTRDPKKT- Copci KKALAAK-IKRRQALLPLEDAINVLRAVEVASPIYELTVTEVGNAVPKGRVNLPREAKKEEKIVVFAE--GKIAEEARVVGGPEL--MESTTVLCTPALIKTITPKLGRHLGPLGLMPSERRGTV-T--EDMALQKLKGTEWRADKAGTI-RVPIAVMNFPVSDVVKNIRHFMISVKGTGPKPVIKKVILSSRGPGIR- Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 --------ARVQKKQLSASEATRVLRALEVAHPTYSLTLTKSHKLPIRGSFTLPLDPRRSETILVFAEPSSPSATLAKYVGGDEL--FEPTRCLATPGMMPAVTRSLARFLGPKGLMPVAKRGGV-AEGEELAIRDAAGKEYRADKQGIV-KVNVARVDFGIPSVESNIKSFIQTVKKKKGSSI---VILESTGPSIE- Crypa2 SGN--KKEKKRRQFKFSLCDAIRYARAFEVGQNKYDLAVLKTLKPVIKSRIRLPHPVRSDRRIGVICKENSALAIQARAVGEESL--FEITSMICDQASADKLAANLGRLLGPKGLMPSVRQKTI-T--SNVLLREMAGQNYR-EKAGVV-RIAIGQLGFTPDMVAANVKAFVAQV-----EQVVHEVVLSTTGPGFSL Debha1 KQNRDQQKSKNKL-KMDVPTALKYLRAAEVGNPTLSILMIIPDKKPISGSVFLPRPIK-DNNMLIFSL-EQESLEQAK-VGGLEL--IEETQCFATPDIVKEL-KAIARYLGPKNLMPSTKKGTV-S--EDISMEENVGAPFK-QRDQHL-SIPIGRCDFSDKEILQNLKAASDAIKKPN----IGQTCLSSTGPSLVI Dekbr2 KRELDAKKKEKKLERMEVPVAMRYLRAAEVGRTSVSIQVVLGERAPLQGAVRFAKPLK-ETRILCLSL-TPEKREEAL-VAANDVSFINDDKIIATPDIEPML-RKVGRVLGPKGLMPAAKRGTV-T--ENVGISNTLGTPFR-ERNGRV-ALTVARCDFRDEDVMRNIISASKAIKKPI----LGNTVLSSTGPGIVI Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba RPAVASVARKKRGMRYSIDEAVRILKALSFTRSKLDIVFCKLEK-TIRGLCNLPVSSSAPLRVAVFAT--GTAAVDAKIVGAEDL--VARDRCYATPDMMPLVV-RVARILGPRGLMPNPKSGTI-T--DNIALRTAQSSEYRADRRGDV-RVSLGTMDFSGRDLQRNIHALYSTI--------VRVAYISSTGPAIGL Fomme1 KAKLAAR-ERKKALKMPLADAVNILRAVEVARPTFELVVTAMKRAIPKGRINLPREVKARDRVFVFAE--GRQADEAKFVGGTEL--VEGTLFLCTPSLIRAITPKLGRVLGPRGLMPSERRGTV-T--EDVVLRRISGSEWRGDKAGTI-RGAIAKMDFPIEDVVRNARHFLSVVKAGP-KPVITRVVLSSTGPGIQ- Fusgr1 IR---KTAKKKPLPKYSLCEAMRILRAVEVGEPKYELHILKTARPVIKNSVRLPHPVQSDWQIAVVCPEGSEIARDATAVGQETL--FEADRLICHEASEAALNAGLGKILGPKGLMPSKRMRTI-V--PDVVMRDSAGADYR-ERQGVI-RLAIGQLGYSPDQLKNNIKVLLAKI-----EEVVHEVILSTTGPGISL Galma1 KKAAAAK-ARRKAALLTLQDAISVLRAVEVAFPTYELTVTQVGNAVPRGRVNLPREAKPEDKILVFAE--GRLAEDAKIVGGPEL--IDGTTILCTPSLIRAITPKLGRFLGPLGLMPSERRGTV-T--EDIAIQRLRGTEWRADRTGTI-RAPIAMMNFPVDDVALNFRQFLASVKSAG-GAFIMKVILSSTGPGIR- Ganpr1 TRSLHEHLRRGKDPRKSLAEA---LAAIELVAPSYVLSRLNLDTVPVRGRAQVPRGVLPEEQVLVFAE-EGPAAEEARVLGKDD---IEKARALATPAMYPLIT-PFGRLLGPLGLMPNPKKGGV-T--EALGIEGARAAKDKDKEGGTV-EVEVGKVGWGAAEVRENIGAVLKAI-----KKKVHSLYLASKHP---- Gloin1 IREYASKSKRRKKEKLPLVDALDILKAYEITYPTLELHVTRLEKSPVRGSVSLPKPISKKVAWLVFAK--GKNAEEAKTVGAEEL--IAEDKCLSTTELYPLVT-KIARILGPKMLMPMVKRGTV-T--DDIVIKRMDDKGFNSDKLGWI-HTGIGKISWTTKEIQGNIQAILKEI-----KKAIEKIAINPNGESIH- Hisca1 SK---KNTKAKKKYKFTLCDAMRWIRAFEVGRPKYEIHVLRSTRAVIRNQVRLPHSVQPLARVCVICPPDSKAAKEAAVIGEEEV--FEQDLCICHTSSLAAMNAGLGRILGPKGLMPSAKLGTV-V--DNIAVKNMRGGSYR-ERMGVV-RVAIGQLGFSPDQLKQNIVTFISQL-----DESVLEVVLSSTSPGFSL Klula1 GTKLTKEQRKREL-RMPVSRALRYLRAIEVGQPTITLTTVVAERPPLTGNVSFGKPLK-DVKVAVFTN-DEAQAALMKLVGGSDL--VSQDKAFATPDIVPQLASQVGRILGPRGLLPTAKKGTV-A--EDLEIKDSMSSPFR-QRGNSI-SLGVAKTHFTDKEVLENLLATQKAFKKPS----LSQTTLTSTGPGIVI Lacbi2 KKALAAK-ARRRAGILTLLEAIAVLRAVEVASPIYELLVTEIKNAVPKGRVNLPREAKPEEKILVFAE--GRQAEEAKIVGGPEL--IDGTTILCTTSLIRTITPKLGRFLGPLGLMPSERRGTV-T--DDIAIQRIHGTEWRADRAGSI-RAPIATMQFPIEDVVKNVRHFLTSVKASG-APVISKVMLSSRGPGIR- Lenti61 KKQLAAK-ERKRAKKMTLSDAVEVLRAVEVASPTYELVVTEMGKTIPKGRFNLPRETKSKDRILVFAE--GRQAEEAKIVGGLEL--VEGTMFLCSRSLIRPITPRLGRVLGPRGLMPSERRGTV-T--DDIAIRRLKGTEWKGDKEGTI-RQPIAKMHFPVSDVMKNVRYFITVVEASQ-KPVITRVLLSTRGPSIQ- Malgl1 EGKLK----GSEAVKLSLSDARHVIRSVEAARPAYELHVTSVPPNAFRGRISFPKDPRIGETVLVFAEQGSETADAAQVIGGNDM--IADSRVLCTSGLLPSMSRSLARALGPKGLMPSAKRGTV-V--DDAEIEQLVTGDWRGDRVGVV-RAAVGRISFSDAELRANVQAFLDAIPGSMKKALVQQVHLSSTGPGIRL Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr TPRVLSSAEGQKPP-FDFESATQVLRALSVNPEHFKVSMDKTKKDPIRGVLVMPNLFRPLRRVVVFAD--GEDAQLARRVGGPEM--LADDIIMATTSMAREIKREGGRVL--RANMPTEKKGTV-V--DDIAVPRVARGSFRSDAHGAI-NIPVAKTTMTVEQIEANVVAAMQGL--------IEQLYLSAQTPGMRV Morel2 QRGYASA-KKAPNTLMTFTDALAVLKAKEVSKPLVEVHITKAEKQPIRTSVLLQKAIKQDSIILVFAE--GKLAEEARIVGGPEL--VKEDKCISTPGMYPSVT-RLARILGPKGLMPTTKKGTV-T--EDISIKAQTAADIRGDKNGVV-HTIIGKVNWDQKDIEGNYQIILEQMLAAE-RFVVKNVYISSTGPGIP- Mucci2 ------------------------------------------------------------------------------------M--IEKDKCIATPQMFPSVT-KIARILGPKGLMPTVKKGTV-T--DDIAVRTSKSSDFKADKHGVL-HTGIGKVNFESEDIEANLKAILEELFGKT-NNLIQNVVLSSTGPGIV- Mydma KKFLEITKDRNKIQRYTLQEAIDTFKAYDLFGGKIDVLLLNTGKGVLKGIIRLPKPVSPSQKVLVLAE--GEAAANARIVGGTEL--IKQDHCLSTLDFLPNIK-HLPRIL--KNKMPNTRRGTA-T--DDIVLQVFLHGSYIADNSGVL-RHTVALTTFKPEEIKDNIKVFLKTI--------FQYLSLIIPGPKLDI Neucr2 NKGGAKKAKKKKQYKFSLCDAMRYLRAVEVGQPKYEVHVLRTKKPVVRDRVRLPTPVKTDTRIAVICPEGSALQEEAKMAGEETL--FEANKLLCHTESEGALRANVGKLLGPKGLMPSGKTKTI-T--NNLEFRDMIGMEYR-ERNGVV-RMAVGQLGFTPKQLAENIRVFMAKI-----DTTVEEVVLSTTGPGMSL Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 GK---EQPKSRKGPQYALCDAMRYIRAIEVGREKYELHILRTKRPVIRNMLRFPHAVQTESRICVICPPGSKAAKEALLVGEDEV--FDADRCLAHPDSLPALNAALGRILGPRGLMPSAKTGTV-V--EDVAVQDLRGGVYR-ERDAVI-RLPVGQLGFSPEQLRDNMRVTLDQI-----DRVIYEVVLSSTGPGFSL Phybl2 TRSYATK-KKKQTTRLDIQGAVRVLKALEVGNPQFEAHVCKVEKPLIRGSIVLPKSIKQEATILVFAS--GKKADEARFVGGEEL--IEKDKCISTPAMFPAVT-KIAKVLGPKGLMPTVKKGTV-T--DDVTVRTSKSSDFKADKLGVL-HTGIGKISFEGEDVEANLRAILEELFGKA-NNLIQHVVLSSTGPGIV- Picst3 ------QQAKRKL-RMTVPQAMRYLRAAEVGQPTVSILMVLPERKPLAGSVYFPKPIK-ESHVMIFSL-QDEKVKIAK-VGGLDL--IESTHAFATPEIVKDL-RAIARQIGPKGLMPAAKKGTV-S--EDIEMQLSVGAPFK-QKEQHL-SIPIGRCDFSDEEIIKNLKAASEAIRKPN----IGQTCLSSTGPSLVI Plicr1 KKAMAAKLKKREKIEMPLNNALAVLRAVEVSRPTYEITITQMKRAVPKGRIKLPRDVKEKDKILVFAD--GRAAEDAKIVGGAEL--VEATIYLCTPNLIRAITPKLGRILGPRGLMPSERRGTV-T--DDIVIDRLQGSEWKGDQSGYI-RYPIAKLHWPIEDVERNIRHFITVVPATG-KPVIDRVVLSSTGPGII- Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 KKQLAAK-AKKRALKMTLAQAINVLRAVEVASPAYELTITGMPKAVPKGRIVWPREAKPRDRILVFAE--GKKADEARIVGGPEL--IEGTTILCTPDLIRAITPKLGRVLGPRGLMPSERRGTV-T--DDVAIRRLAGSEWRADKEGTI-RAPVGRMHWPIDDVMTNVRHVLNLVKDKD-IPVITRVVLSSHGPGIT- Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 EKARVYSAERKRRAELPLDEAAKVLQAWTPLQPSYDINVVKPTGNAIRGRAFLPHSCANHEVIVVFAS--GKQAEAARIVGGQEL--VDDDKLITTNELLPLFQPTLARTLGPRGLMPSVKRGTV-T--EDVVIQEARGGDWKGDSRGVV-RAVVGRLHFNPDQLAENVHTLLASVGGSVQRQRITRVMLTSTGPAIE- Rozal11 --------QEKEEQKLSIQEVASVLKAYAVGLSTIKLTIINTDR--LRGFIQMPYFKSPNVKIAVFAQ--GQMADIAKNVGGEDL--REKSHVLATPDMMGVVR-KVAKTLGPKGLMPNSKLGTL-T--NEIEINTCFKSPYKAVDGGLV-SIDVGQVENPENHIQENIKKVMETI--------FRRILLNHDGYPLEV Sacce1 APSLTKDQKKREL-KMPVTKALRYLRAAEVGRPTINLTTVVGERAPLSGSVTFPKPLR-YIKIAAFTN-DESKLEELRLIGGADL--VAKDKAFATPDIVPALQSQVARILGPRGVLPSVKKGTV-S--DDISLQESLGSPFR-QRGNSI-SIGVGKCYFTDREILQNIISARAAFKKPN----LSKTTLSSTGPGIVI Salro -PATESEQSQANPPA-NHMLAIRTARAYSISNEHIKVSMDKTKKDPIRGMVILPHLFKPAQKVIVFAR--GKDIDDALAAGLTDL--MEQDVALATADVMRDI-RAAGRSL--RQRMPSAKNGTI-V--ENVKVLRFSRGLYRTDAHGNV-NIGFGKADQSMDVLQENLLALTENV--------IEQMYISSDSGGLEI Schco3 KKAMEAK-RRRKAALLPLAEAIKVLRAVEVASPSYELFVTTLGSAVPKGRVSLPREAKPEDKILVFAE--GKKAEEARIVGGTEL--IEGTTILCTPDLIKPITPRLGRILGPLGLFPSERRGTV-T--DDIAIKKLAGTEWRADKAGNI-RAPIGMLHFPTEDVVNNFQHFMASVGGEV-KRIIAKVMLSSKGPGIR- Schpo1 RQTLLSHNNQKGFCKMTVPEATKYLKSVSISVPSYMLSILKSNRPSARGQIAFPHPFQEPPKICVFAK--GAAADEALYVGAEDL--VKKSKCFAHPNSAELLP-QVAKLLGSKRLMPSIKRGTI-S--DELKIESALTADYRQNDAGSI-NLPVGKLGFSDKELQENIEALVSNV--------VKHVHLSASAIAIPL Sorma NKGGAKKAKKKKQYKFSLCDAMRYLRAAEVGQPKYELHVLRTKKAVVRDRVRLPTPVKTDTRIAVICPEGSELQEEAKLAGEETL--FEANKLLCHTESEGALRANVGKLLGPKGLMPSGKTKTI-T--NNLEFRDMIGMEYR-ERMGVV-RMAVGQLGFTPKQLGENIRAFMTKL-----DSTVEEVVLSTTGPGLSL Sphar --------------------------ALAVNTW------DKKKKHIVRGSVILPKSVGKDKKILVIAE--DEEAEKAQLVVGSDE--IPNDLILTTPEMLKAL-RPAARKL--RGLTPTVKKGTV-L--TDIAVKKFRNSEFKTTKTGVC-NVGLGKLTLDNESLKANLLAYLSGI--------LQKVHLTTSGPSVEI Spipu1 GPTLVSTVDRKRYLRVSFEEAFSVFRTYCLGE---DRVVIQVHRRTVRGEVNLPTQVSAKSVILVFAK--GEQAEEAKIVGAEEL--IEEDKVLSTKAMFPEVV-KIARVLGPKGLMPSPAKGTV-S--DDIPMSALRASKFEVDADGFV-HLEIGKTAWRDEDVFENIRALLTAI-----TDAIESVNISAKTPGLKL Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 ---------------MTITEATRYLRASEAGYSSLHLAILKCDKVPLRGSIALPRQLPTKTKIAVFAR--GQDAIAAKVVGAEDL--VKRNKCLATPECVPLIA-KLARTLGPKGLMPNVKRGTV-T--KNVAILAADRNDFRQRSGDVV-RMPVAHTTFTDEEIEKNIKAVLKKV-----KGVIDQIVFSSTGPGIP- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 --------GRTTSSKMSTSDAARILRAMEISNPAYSVTITRISKLLLRGRVSLPTDARKPEVIVVFADPDSPSATVARYVGGADL--FPLTKCLSTPGMLPEVSKALARYLGPRGLMPVAKRGGV-GEGEELGIREAGGADWKADKLGVV-RAPVARMDFDLPAVENNVKAMIQTVKGKRGKSR---VQ---------- Trire2 TK---KV-KKKAVPKFTLCDAMRVLRAVEVGQPKYEIHILKTARPVIKNSIRLPHPVQSDWQIAVICPEGSDIATAATAVGEETL--FEADRLICHENSEKALNAGLGKILGPKGLMPSKRMKTI-V--SDVVIRDSAGADYR-ERQGVI-RMAIGQLGYTPDQLKANIQALLKKV-----EEVVHEVILSTTGPALSL Umbra1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 QGGLATAAGGKSSQKLQARGA--------AKRPAFEVHITSVSSNALRGRIAYPKDPRTQERLLIFAEEGSDAAEAVKILGGSEL--VSQTKVLCTNTLLSEVSKGLARSLGPKGLMPNPRRGTV-VPSDDRKIRESKGADWRSDKVGVI-RGAVGRLNFGKQDVRNNVTTLLDAIPGELKKAAIKQVHLSSTGPGIKL Walse1 QKSIINNAKAKQSAR-SVIDACTQLKQTDSKRPAYELVVTKKEKIPLRGMVELPHDPRKREVVLVFAE--GADAKAAKIVGGEEL--VGDTKALAHPSLLPQVQKNLARMLGPKGLMPAEKRGTV-T--TELAINEARGKTWRGDRIGVV-RLGVGRIQFDSNQVEENIKKFIDGL-----RRLIEKIYLSSTGRAYEL Zygro1 GSKLTKEQRKREV-RMPTPLALRYLRAVEVGYPVITVTTVVADRPPIAGNVSLPSPLK-DVLVAVFSN-DEQQLSMARLVGGSDI--IAKDKAFATPDIAQELTSQVARILGPKQVLPMAKRGTV-A--SDLEIKDSFGSPFR-QKGNSI-SLAVAKCEFSDRQVLENLLAVQTAFKRPS----LGRTTLTTTGPGIVI [Cluster2851.fasta_al_trimmed; alignment length = 298] Allma1 SQATRRLKRHTH--QTYHILRSIDEDAKFV-V-PIVA-NLRCGRWYSP-PDTCYLKSTDGHYGKWDLPMRRLNLHLLKVLDEQGVIIIDSTRRGKRF-PDALTRTVPLWCAAMNALLLCTLPSQVSASESAAMA-AHLSILPRLRAIKLP---ARPKSLRPLWISPSSFIPVYCVCVSRNYVYIQGAADDEENWAGLTPDLFWS--HRAAFL-SADSCDALASLSTLPTVINCTE-GKKGVLVHCNQGMDRSV--TVALLLLVSKDDMRAALLFVTEHHPRARG-------------- Ashgo11 NHINKEIKKEYT--SLRNRLRSILCDNKFLLE-PLVP-NERCGLWYCS-PETCYFKSTDGHVNGWDFSVRRLNFHLLPLLAESGAIIVDSTRRGKKI-PDALSKTIPIWCAVLNTLILFCPPGTVSQLEYNRIQ-AKLPVQKLKRVISGAELCSLLRLLRPFWVYPGAIPLILC-----GYAYVQGAADDHELWAGLTPSLFWA--NVQLLADPEQLLQGVERIVELHKVVLCGSGCKKSVLICCSSGSDISV--GIVLAALMTKTIIKKHLIKLTSKIHIINPSRTTLNSVNAFLM- Aspfu1 SQTLSSLRRSAL--SISNRLRSIESDAAFV-A-PLVA-NERCGSWYIS-PDSAYFKSTDGHTGQWDFSFRRLNLQILPLARQGGCIIVDSTRRGKLM-PDALSKTVPIWCAVMNRALL--PPNYLGASEESQIE-RRIDVKSLKDLLDLDDLRQQLKPIRVAWANRSYYNLFVLCSASKG--YIQGAGDDSEGWAGLTPPVFWA--HKAILLKPEEDLPEVEELVKEHRVIDCNL-SKLGLLVTCETGKDLSA--GALLAIMIDKQFIRQRLAWILSSKHDVNPSRPTLQSVNAFLME Aurde31 ----AELRRESV--DVYNRLHSIDEDAQFV-S-PLLP-NLRCGAWYTD-PKPVYFKSTDGHFGQWAFNLRRANLHLLSLVEQGGVILVDSTRRGKRL-PDALAKTVPIWCAVINCAILFTPPATVSASEHDQIK-SHIEANELLASYTLP----RLRPLRPFWVTPSTFFPIICVSASKGYVYVQGSGDDHELWSGLTPHVYWK--HRDALLSARAALPEISSLLSST-LCVASQ-GKKGVCIACEDGKDVSV--GLAVAVLATKDSIRKRLQWVLESRPGANPARTTLKRVHEFLMS Batde5 ----EQVRNDNK--SIYNRFRSIQHDANFV-R-PVVA-NERAGTWYTDPKLSAYFKSTDGHHGQWDFNLRRLNRPLLELITATGCILVDITRKGKRF-PDSLAKTVPLWCAVINRATLHC-PSNVSQSEHAQMS-ELIDAEKLLTSADLTLIYKQLKPLRPLWITPVTFYPVICVSASMDFVYIQGAADDSEMWAGLTSSLFWEYINSHELLQTPQQCHHIHQLISQSQIINCGE-GKKGILVHCMQGRDRSV--GICLALLLDKDTIRNRLLYIQRFRMVASPSRATLKKINLYFLE Botbo1 ----HIIQKEKT--DIYNRLRSIREDVEFV-T-PIVA-NQRCGAWYLD-PAIVYFKSTDGHTGQWDFNLRRANLHLLPLIECGGIIIVDSTRRGKRF-PDALSKTIPIWCCVVNGALLYTSQAAVSRSEHSQME-FRVGIKKLTASFTLS----ALKPLRPMWLSPA-FFPVICLSASKGFTYVQGSGDDHELWSGLTPRLFWE--HAKALLESRTELPSVRALVEQS-FHLGVP-GKRGVLVASQKGDDTSL--GIAIVALVSKASIRKRLELIQQRIPDANPSRTTLKRVNEFLLT Botci1 SKTLGEIKRSTL--SIHNRLRSILEDAEFA-Q-PLVA-NERCGSWYID-PSSAYFKSTDGHTGVWKFSSRRLNLHLLEII---------------GM-PDALSKTIPIWCCVLNRVFA--PPQVVSDSEQAQMA-NLIPVQAFQTLLPIESFREKIKPIRPIWMTPESFHPVVCCTVSRG--YIQGAGDDTENWAGLTPNIFWS--NQEILFESEEDLPGIETLINQTS-----A-KKVGIVVACESGHDLSV--GVALALLVNKDFIRQRLTWISTSMPDANPSRATLQSVNSFLMS Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 NEINKDLKKSSL--SLKNRLQSIVHDQYFV-R-PLIA-NERCGLWYVP-LNTCYFKSTDGHTNVWSFSLRRLNLHLLPIILEGGVVIVDSTRRGKLM-PDALSKTIPIWCAVLNSVILRTPSSMVSKSEHNSIE-KLIPVASVKQMLEGFKL----KPLIPSWYYPGAVYNICCISASRSCDYIQGSADDHELWVKFGADVFW----------AGDLLEDIK--CGETEIILFHS-NKKGCTILCDTGRDLSV--GMALVLLVTKTLIKQHLSKISQI--KVNPSRSTLQSVNTFLF- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -----------------------------M-T-PEVF-------W--------------------------ANKHLVLESAE----FLGKLRAAKGAEANALVTWVP-------------------------------------------------TPL-----------------------YIAASADETNPWA----------------------------------IVNCTD-GKRGVLVHCNHTRDRSV--AVVVMLLVDKEEIRRVLVWLANHYPRAMPSRASLKQLNRYLIP Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SSTLSSLRRSTL--STHNRLASIISDSAFV-E-PLVA-NERCGSWYIP-PYSVYFKSTDGHMGEWSFSLRRLNLQLFDVVEKGGAVVVDSTRRGKSM-PDALSKTIPMWCCVMNRAVLFTPPQAVGESEHAQME-KRIDVQQFLDIPNIPLLRSKLKPLRPIWITQKSFHLIVLCTASRG--YIQGAADDHEAWSGLTPSLFWE--NKDILMRNEEDAPEIAKLIKEQKVISCTT-GKLGILVCCPTGKDLSV--GAALAILMDKSFIKQRMSWITTSNAALNPSRATLQSVNAMLLS Coere1 YQISEELRRESR--SIYNRLKSIEDDANFI-E-PIIA-NERCGVWYVK-PQTVYFKSTDGHHGKWSFNLRRANTHLFDILAIKGCIIVDSTRSGKRM-PDSFSRTIPIWCSVWNMAIVHTPTNIVSESERLQIE-KLIPVNILLASIDVKWAATRLRPLRPIWITRDQFTPIICLCASI-FGYVQGAADDHELWAGLTPHLFWK--HRLQLL-DRDYCDEVEKLIAREAIINCGE-GKRGVLVHCSQGMDRSV--GIALAVLITKLSIQNKLLWITTSRAKANPSRVTLKQVNRHFLD Conco1 NKQFRDIKKNKR--SLFNRLNSIYYDSKFV-D-GIIA-NLRCGSWYIN-PRECYFKSTDGHFGKWDFSLIRTNFHLLNLIKDKGLMIFDSTQKGKQF-SDAQSKTIPIWCCVLNRSIFHSVPSIISKEEANYIE-LKLNVQKVMR-IDLSSIASLIKPLRPIWISPQTFYPILCISTSENFDYVQGAGDDEETWCGLTHKLFWH--HLDLILNEEFELDEVKDLVLNSNIINCCE-GKKGVLFHCAQGVDRSV--GMALIVILNKTSINNNLNFIMRYRIKANPSGHTLRRINEYLIK Conpu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ----SHIRKESL--DIYNRLHSIKEDVEFV-N-PLLP-NLRCGAWYTD-PTPAYFKSTDGHYGNWSFNLRRSNLHLLAFLEQRGLILVDSTRSGKRI-PDALSKTVPIWCAVINRALLYTPPSVVPSQEHNSIL-AKLDAEALANSFDLP----KLYPLRPIWITPSMFIPIICVSASKGFSYIQGSGDDHELWGGLTPELFWS--HKDELLSSRSDLPEVEDIVSSASIWIGKS-SSKSVCIVCPTGKDLSV--GVGLVGVLTKKDIKTRLEWIIASRPEANPARATLKRVNEFLFT Croqu1 RTREREINKQQK--DIYNRIHSIAEDSEFV-L-PVIA-NQRCGAWYVN-PESVYFKSTDGHDGQWQFSVRRSNLHLVSVITDKGVLIVDSTRRGKRF-PDALSKTVPAWCAVLNLARLSTPPKAVRASEHDQIR-KKVGAEELLSSFDFRRSLLQLRPLRPVWCCPASYYTVVCVSASKGYNYVQGAGDDHEAWSDLTPKLFWK--YRKRIMSSRHDLPEFQDILGE-ELVSASV-ST--VCI-IAGSQQFVV--AIVICVLIDKALIRSRLQWMIEASDKLNPQRSVLKRVNNHLIA CryneH991 ----RAIRRRAAQHDLFNRLHSIAADEEFV-R-EIVP-NQRCGNWYCD-PAYAYFKSTDGHMFHWNFNLRRSNLSLASYAEAGGLILVDSTRQGKRM-PDGLSKTVPIWCAVINIAVIYLPPQIVPPTERSQIE-SKLRAESLVRSLPLP----HLRSLRPFFIHPSTYIPIICLSTSRGFEYVPGAGDDDELWAGLKPLLFHQ--HKKDLLSERDDLPSVDRLVRS--MALDIS-AKTDITSPSSSARKVIL--PLALVILLSKDLVADRLHRLVALWPDGNPPRVALKRVNEFLMS Crypa2 NRILGDLKRSNL--SITNRLRSVQQDADFV-D-PLIA-NERCGSWYIR-PGSAYFKSTDGHTGQWRFSTRRLNLHLLPIIERDGIIIVDSTRRGKRM-PDALSKTIPIWCCVLNRALV--PPNAVSDSEKSQAL-ARIPLAAFKELLDLDSLCAQIKPLRPTWVTQETFRPVICCTSSRG--YIQGAGDDTENWAGLEPPVFWA--NADELLSPEADLPDIRSLVASAKPQRLMK-HKVAILVACDTGRDLSV--GVALALLFNKSLIKIRLGRIMTTMPDANPNRATLQSVNSFLMD Debha1 NSVTKELRKDSL--SIKNRLQSIIYDALFV-E-PLIP-NERCGLWYLP-PNTSYFKSTDGHTGQWSFSLRRLNFHLLPIISAGGIAIIDSTRKGKLM-PDALLKTIPIWCAVLNTILVSTPKYMVFASERNEIS-KLIDAKEVKKLVTKEKLMLHLKPLIPQWHYPGCYFLVQCVTASKSWYYIQGSADDHELWANLNSGFFWE--HI--FADNDDIIDNIYDWISENELVILSS-SKKGIMILCDTGKDISA--GLVLVLLINKDLVKQQVGLLLNV--KVNPSRNTLQSVNTFIM- Dekbr2 RKKEKEERKSNL--GLKNRLLSIIHDHRYLIKIPLIP-NERCGLWYMK-PSTTYFKSTDGHNHEWDFSLRRLNFHLLPLLEQDSLGIVDSARSGKRI-PDSLSKTIPIWCAILNKASLVLPPD-ISPLERSEIL-AKLPFQKFQSL----MLKPIIRPLRPVWIYLGC-PLFLI-----HFTYIQGAADDHELWAGFDYRMLWE--NIHLFTDSQDEVSRCQMLVESKHIMIFDSRTKIAILLVCRTGDDISI--GVLLACIIDKKLVHKQLARIVEK--RVQPSRATLNSVNYYLM- Dicdi ---KRIVFKGEL--GVFNRLQSIYHDSNFV-E-PLIA-NLRCGLWYSE---KVYFKSTDGHYGNWSFSTNRLNLHLLDIVNKNGAIIVDSTRKGKKF-PDSFSRTIPIWTCVINRVLLNM-PGWVSDSEKDQVENKVVNVNQLLECADLSGFCKSVKPLRPIWICVESFHPLYLVSCSD---YVQGAGDDEEQWSGLTPQLFWS--NHKEILANRDYIEDISQLLLDSKILNCSE-GKIGILIHSTTGKANCV--SIIMAIIVEKIDIKISYLFIEKYCSQSLPCKSMRLAVNKHLMS Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------DFWNRLCSIAADALYV-E-VTLP-NMRCGGWYAR-PRVAYFQSKDGHHGQWTVSPRRANLGVLDLAAGGGCLLVDATASARKVTSDALAKTVPFWCAVMNRTALHTHPS-IEPTE-RDLMRRAVPARALVGLDPLQRILRALRPLVSTWLDAPGYWTLWCLGASGAYDHVRGAGDDHELWSFFTPELWWA--HRLELLAPAEYLTAAAVLLSAPAFI---V-GRALAVISCDTGTVVAPLLVAALLAAVTREALHGALLHVTGAFPAADIPRPLLTRLVFYFTG Fomme1 ----TQIRKQSL--DPYNRLHSIAEDIDCV-Q-PLLA-NLRCGAWYAD-PRTTHFKSADGHYNAWSFNLRRPNLHILPLILDHGICIVDSTRSGKRM-PDSFAKAVPIWCAVINRALLYTPPQSVSKQEHSQIA-DKLDADELARSYSLP----NLKPLRPIWITPATFYPVICISASKGYSYVQGAGDDHENWSGLTPETFWR--HKDELLFSELDFPDLKKMVNLNELSICKT-DKKGICVACETGTDLSV--GVVLVALVNKETLRARLHWIIASRPESNPSRATLKRVNEFFMP Fusgr1 SQLMASLKRTTL--TIHNRLTSIQTDAEFV-D-PLVA-NERCGSWYIP-PESAYFKSTDGHERAWKFSTRRLNLHLVEIIEKDGIIIVDSTRRGKRM-PDALSSTIPIWCTVLNLAIL--PSH-LPATTHSQIS-TLIPVASLKALLNLPT---CLKPLRPFWVTPDSFRPVICCTASRG--YIQGAGDDTEMWAGLEAPLFWE--NVDELLESEAELPDISRIVDEQAP----K-SKLAIAVACESGKDLSV--GVALAISFTKNLIKSRLGLIMTAYPGANPSRATLQSVNSFLMD Galma1 ----SYLRKETL--DIYNRLHSIQEDVAFV-N-PLLP-NLRCGSWYTD-PEPAYFKSTDGHFNNWSFNLRRSNLHLLPLIAERSMILVDSTRSGKRI-PDALSKTVPIWCAVINRAILYTPPSAVSMQEHSQIE-QRLHAESLAASFSLP----ILSPLRPLWITPTNFFPIVCVSASKGFSYIQGSGDDHELWGGLTPEMFWT--HRDQLLKERTQLLGVSRIVSLR-LLLCTS-GKKGVCVACESGKDLSV--GIVLAAL-DKNSIRTRLEWIIASRPQANPSRTTLKRVNEFLLT Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----------------FNRLKSIFEDAKFV-S-PVIA-NERCGTWYVD-PTTVYFKSTDGHTGKWAFNLRRLNAHLFSIIIKGGCIIVDSTRRGKRI-PDSQSKTIPIWCCTINNAPFHSLPSLISKSEHNQIA-SLIPVQKLLNSFDIQSLSNKLKPLRPLWFTPSSFYPVICLSASKGFLYVQGSADDHEMWAGLIPPLFWK--YHEEILNNFIECEKVSQFIQQERIINCTE-GKKGILIHCKQGIDRSC--GIALAIM-RKEYIQNKLLYILSYRTKANPTKSTLKKINIYFMS Hisca1 SQILSSLRKSAL--SITNRLRSIEEDSEFT-E-PLVA-NERCGSWYIP-TDSAYFKSTDGHEGQWDFSLRRLNLQLLDILREGGCVIVDSTRRGKSM-PDALSKTVPIWTAVLNRALF--PPDFLGASEESQIE-KRIDVISLNSLLNMQGLQSRLKPIRLTWATREFFHLIVLCSASRG--YIQGAGDDSEAWSGLTPRIFWD--NRSTLFAVEEDLPAIAELIGKHHRIKCNS-GKLGLIVTCDNGKDLSA--GAILMIITPSSTLSSVFRVTIPS----SPHLMTKSSALAFAWT Klula1 KEISKELRKEDK--SLKNRLQSIIFDNNFLKE-PVVP-NERCGLWYCD-PKTSYFKSTDGHMNQWDFSTRRLNFHLLPLLGEGGLVILDSTRRGKKI-PDALSKTVPIWCAVLNYLMLFVPPSTVPESEFDRMF-AKLPVQKLKKLIDVKKLRKSLKLLRPIWVYPGSIPVILC-----GFTYVQGAADDHELWANLTPQLFWE--NIDELGDSDAELKDYNAVILRAKVVLCHSGSKKSILIACDSGKDISV--SILLVALVNKTIIKKHLAKIIESLQNVNPSRASLNSVNSFLM- Lacbi2 ----AYLRKESL--DIYNRLHSIDEDVDFV-Q-PLLP-NLRCGAWYTA-PNPAYFKSTDGHFSNWSFNLRRANLHLLPLVIQNGMILVDSTRSGKRI-PDALSKTVPIWCAVINRAMLYTAPGAVSAQEHHQIE-IKLDARALVASFELP----VLHPLRPFWITPSTFLPVICVSASKGFSYIQGSGDDHELWGGLTPELFWA--HNDALLSDRSELSEVAKLVKQPTLAMCWH-ERKKVCIAIPKARDVAV--GIMLVVLATKQTIRTRLEWVIASVPDVNPSRTMLKRVNEFLLS Lenti61 ----AYVRKESL--DIFNRLHSIAEDVHFV-G-PFLP-NLRCGAWYLN-PKAAYFKSTDGHFGNWSFNLRRPNLHLLPLIAAGGLVLVDSTRAGKRI-PDALSKTVPIWCAVINRAMLYCPAGAVSEQERSQMK-ARLDARDLSRSYCLP----YLRPLRPLWITPSTYSPIVCVSASKGFSYVQGSGDDHELWGGLTPQLFWE--HMDTLLTDREDLPCVAKVIAESKVLIGAE-GKKDICVCCDSGRDAGV--GIALAAIPSKESIRTRLQWIIASRPAANPSRVTLKRVNEFLLS Malgl1 -------------------------------------------------------------MHQWDFSMKRANLHLIPLIQPTGCVLIDSTRRGKRY-PDALSKTVPIWCAVLNRASLQIPTDTVSLSEAAQIE-ARLDVHKFCASLAVP----CLKPLCPVFVHAP-HIVLVSVSPSE---YVQGAGDDHEAWAGLTPALFWR--HHRELLAQREDRVKVHKLVREERIVHCSA-SKRGVLVCCSDGCQLSG--AVAVAILISKDDTQRRLQWITGSVHQTSPSRAHLQRVNAYLMG Mellp23 REQEKEVNKQQK--DIYNRIHSVAEDCEFV-V-PIIA-NQRCGAWYVD-PASVYFKSTDGHDGQWQFSVRRSNLHLVNLIIDKGVLIVDSTRRGKRF-PDALSKTVPAWCAVLNTVRLSTPSDAVRASEHDQMC-QRIEAKELLSSFDFRRSIAQLRPLRPVWCCPTSYYPVVCVSASKGYTYVQGAGDDHESWSGLTPTTFWK--HSTKILSSRHDIPNLREIFAEQELVSTSQ-SV--LCV-IAGSQELVV--AIALCVLIDKSLIRSRLQWMIEASDSLNPSRSVLKRVNNFLIP Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr YHWTRRIAREQY--TLANRLLSIEEDAQYL-R-PLYA-NLRCGRWYAA---CVHFKSTDGHRNVWHLAHRRLNLHLIATLRQGAVLVADATRKGRTL-PDSFSRTLPIWAAVISMLALHMPPTTVPPSEQAQVA-AVLELQALLAAIDLSALL-ALRPIRCLWFHRGQAYVVACVCVSEGFLYIQGAGDDEEMWCRLEPDLFWR--HAPHLLEREGQSDAILEAAQRCQ-----T-NAAGVVIHSTAGQD------------LTAFLAEHPVTHVNAALPPAKRHRYELRDMAPALLE Morel2 GRNRDDMRRDAK--SLLNRLRSIQADASFV-S-PVIA-NERCGTWYVH-PSGVYFKSTDGHTGIWDFNLRRYNPHLISTIIKGGCIIVDSTRKGKRV-PDALSKTIPIWCATINNAVYHSLPSLISRSEHVQIA-DKIEAEKLLRFTDMTPLTTKLKPIRPIWLTPQSFLPVICLSASRGYLYVQGSGDDEEMWSGLKPELFWE--NEEYLLESPAECEQAVEVVKEAKVINCGE-GKKGILVHCQQGMDRSV--GVSLALLASKEMIQRRLFQIMSHRLAARPSRATLKMVNTFFMS Mucci2 NFESKLIRNDNK--NIYNRLCSIVDDATFV-M-ALIA-NERCGSWYID-RTSAYFKSTDGHMHIWDFNIRRNNLHLIPILMRNGCLIVDSTRKGKRI-PDALSKTIPIWCCTVNRAVLHTLPSAVSRSEHAQIE-ARIDVDKLLTSVDMKQLVSQLKPLRPIWFTPQSFCPVVCLSASEGYLYVQGSADDEEAWAGLTHSAFWK--HRHDIL-SSSECERVKSLDSS--VINCSD-GKKGILVYCATGKDHSV--GILLSILVDKKMIQHQLVQIISNWEKAAPSRVTLKRINTHFMS Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 SKILGDLKKSNL--SITNRLKSIQHDAAFV-H-PLVA-NERCGSWYID-PQSAYFKSTDGHTGQWKFSTRRLNFHLLEVIGRDGCIIVDSTRRGKRM-PDALSKTIPIWCTVLNQALV--PPTVVSSSEHSQMS-SRLPLSSLLALPDIPSLRQNIKPLRPLWVTPDDFHPVVCCTSSRG--YIQGAGDDTENWAGLTAPLFWA--NQRQLLEPEGDLPGIEMLVANSE-----K-SKTAIVLLCESGRDLSV--GVALALYHNKASIRVKLGHIMTAFPDANPSRSTLQSVNSFLMD Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SQTLSSLRQSAL--SVANRLQSIETDAAFA-Q-PLVA-NERCGSWYIP-PTSAYFKSTDGHTGQWDFSFRRLNLQLLPLAREGGCVIVDSTRRGKLM-PDALSKTVPIWSAVLNRALL--PPDYLGASEEAQIE-NRIEVHSLKSLLDLDNLRQQLKPIEIAWANRTYYNLLVLCSASRG--YIQGAGDDSEAWAGLTPPVFWA--NQAVLKSPEDELPEIARLVAEHKVIDCNS-GKLGVLVTCENGKDLSA--GTLLAIVISKQFIRQRLAWLVSSKHDVNPSRATLQSVNAFLMQ Phybl2 HSETNQLRKDNK--NIFNRLKSIEEDASFV-N-AAIA-NERCGSWYID-RSSAYFKSTDGHTGQWDFNLRRNNLSLIRTIATGGCVIVDSTRRGKRI-PDALSKTVPIWCAVINRALFYSLPSIVSRSEDSQIT-SKLDAERLLSSVDMQPLEGLLKPLRPLWFTPQSFWPVICLSASQGYLYVQGSGDDQEAWCGLTHSLFWK--NREDLLDSAVECEDVRALVKSSKVVNCTE-GKKGVLVHCAKGQDRSV--GIALAILVDKQVIQHHLLSIISSRPKASPSRATLKKINTYFMS Picst3 SDIRKELRKDTL--SLKNRLQSILYDSKFV-S-PLVP-NERCGLWYVP-NDSSYFKSTDGHTSEWAFSMRRLNLHLVPIIGEDGISIIDSTRKGKLM-PDALLKTIPIWCAVLNSILLRTPREMVFRSEHNLIV-KRIPVKEVKHLISKKQLIAALKPLVPFWTYPGNYYTIQCVTASKSWRYIQGAADDHELWANLLPKIFWS--LL--LI-AEGIIDEIYDWLSEAEVVIFSS-SKKGILVLCDSGKDISA--GLVVLLLVDKDLVKKQLSLLANV--KVNPSRNTLQSINTYLM- Plicr1 ----AEIRRESQ--DICNRIHSIAEDSTFV-E-PVLPANLRCGAWYTD-PRAAYFKSTDGHYGNWSFNLRRPNLHLLSLIVQQGIILVDSTRAGKRM-PDALSKTIPIWCAVVNIAVLYTPPGTVSAQEHAHIS-ARLSAESLFASYDLP----RLHPLRPLWITPATFLPVICVSASKGFMYIQGSGDDHEVWAGLTPKVFWM--HREKLLRPRSDVSSIAAILAND-LLVGAP-GKRGVCICCESGTDISV--GVALAAACSKESIRTRLEWIIASHHTANPTRATLKRVNEYFLS Polpo HSIHRRVDRQEN--SLFNHLRSIDLDSKFV-N-ALVA-NLRCGAWYSA---SCYFRSTDGHYGNWRFSLTRLNLNIIDLVLKDGCLIVDSTKRGKKF-PDSFTRTIPIWIAVINRCLLYT-PKWVTDSERDQML-KMVDCKLLMEHLDLKSYSSRLKPLRPLWLSVETFHPLYLLSCSD---YIQGAGDDDENWSGLTPQMYWS--NHKEIMSNDEQLEQIQQLVKSERIINCSE-GKLAILIHSINGLQNCV--CVLSVLLLTKSDIIKLYLFLEKQSPSSLPHKSIRNAINNYLLS Pucgr2 QADLKAINKQHR--DVYNRLHSISEDSEFV-T-PVIA-NLRCGAWYID-PSTAYFKSTDGHDGQWQFSLRRSNLQLLHVIISGGAILVDSTRRGKRY-PDALSKTVPLWCAVLNAGRLTTPVNAVRSSEHDQIQ-RLVDADQLLASFNIEDTLAQLRPLKPIWVSPA-FYPVICLSASKGFDYIQGAGDDHEGWSGLTPKLFWE--NRLQLLSNRPELDSIDRIVSS-SIISG-V-AVSKVRL-TAISKEMMV--AIGLCLLIEKVDVRHRLHWMIEASKTINPPRSILKRVNNYLIG Punst1 ----DFLRKESL--DIFNRLHSIDHDVRFV-Q-PLVP-NLRCGAWYAD-PRPAYFKSTDGHTNNWNFNLRRPNLHLLPLIQETGIIVVDSTRSGKRM-PDALSKTVPIWCAVINRALLYTPPGVVSPSEHSHIE-ALLDAESLRASYELH----KLLPLRPIWITPSTFSPVICVSASQGFSYVQGSGDDHELWGGLTPSMFWA--HKEDILSARSELNEVRNIVKRSAILLCAP-GKPGICICCESGRDLSV--GVALAAICTKKTIKTRLEWIIASRAEANPSRATLQRVNEFLLS Rhior3 -------------------------------M-ALV---------------SAYFKSTDGHMHIWDFSIRRNNLHLIPLISQHGCIIVDSTRKGKRI-PDALSKTIPIWCCTINRAVFHSLPSVVSPSEHAQIE-SKIETDKLMQSIDLISVSDQLKPLRPIWYTPQSFWPVICLSASEGYLYVQGSGDDQEAWSGLTPTLFWN--HQEYIL-NKTDCEEVKELVKE--IINCSE------------GKDHSV--GIALSILVDKKVIQHQLVRIISSWEKASPSRTTLKKVNMYFMS Rhoto1 QADRGAIRGQLR--DTYNRLHSLAHDAAWVHS-PLVA-NQRAGAWYVK-PSHAYFKSTDGHAGEHNFNLRRANLALLPLIKEGGIVLVDSTRRGKRL-PDALSKTIPLWCATLNRARLYTSPQAVGRSEHAQIE-AKVDAKELASSYDLS-SLKALRPLRPFFVSPT-CYPVICASASKGFTYVQGSGDDHEAWSGLTPSVFWR--HADEILAPREEIDQIEQILAEEDISISTP-GKAGVCILVEKANDLGV--AMSLILLITKDLIRTRLQWILEAFPTVNPSRAALNRVNDFLMS Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 SQINKDIRKENK--SVRNRLQSILLDNKFLQD-PLIP-NERCGLWYCN-PSTSYFKSTDGHVNQWDFSTRRLNFHLLETIRDKGIIIVDSTRRGKKI-PDALSKTVPIWCAVLNTLMLYLPPETVPKSEYDMIK-RKIPVAKLQKLIDSKKLNELFKLLRPIWVHPGSIPIILC-----GFTYVQGAADDHELWSGLDSNMFWA--HIEYLGDSDDQLHDIMDL--AAAVIIFSSGDKKSMLICCNTGTDMSI--GVILSILISKLIVRKHLTKLISHLKNVNPSRATLNSVNSFLM- Salro AQVMRAVTQEGL--SIYNRLRSIDADVEFV-D-PIVA-NLRCGGWYF--PEEVHFKSADGHRGQWQVSLKRLNLHLLPLLAEGGCVLVDSTRKARTL-PDSFSRTVPMWCAVMNRLHLHCPPTTVPQQELCQMQ-DLLDVHAVLESVDLS-LLKNLKPLRATWVTTETYTAIVCLCASEGYVYVQGAADDEETWSGLTPRLFWQ--HKTDLLDDSDTCGDVRALVSQQMVVVCLA-GKRHILVASGDSNDRAP--TVATAVLLTKQDFTRALHCIRQRVPSACPSRHNMRKLTSFFLS Schco3 ----EHIRKENL--DLYNRLHSIDHDARFV-D-PLIP-NLRCGAWYTS-PSPAYFKSTDGHTNNWSFNLRRANLHLLPLIVEGGLVLVDSTRAGKRM-PDALSKTVPIWCSVINRAVLYTPLLVVSRQEHAQIE-EKLDAIDLAQSFSLP----DLLPLRPVWITPAS-LPIICVSASRGFAYVQGSGDDHELWGGLTPAIFWK--HHREIVATRDELAPVDRLCAAV-IW--------------------------------------------LASTP------------------ Schpo1 ----QQIHVQAR--HPKNRLLSIAHDAKFV-D-PVV--NERCGTWYVN---SVYFKSTDGHTGQWSFSCRRLNLHLLNEITTDGLIIVDSTRRGKRM-PDALSKTIPIWIATLNKCVLAFLPPFLPDTEKSSIL-QRLDVDSLMQSIDLDALAAKLKPIRPLWVTPASYFTVVLVTASAGFLYVQGAADDEEEWSGLTPEVFWQ--NTESILTPEEQLEQISLLLSSTRNLSNTS-GKKGIFIVDEGAKEAAS--CLALMILLTKQTVRQFLVKITELHSKTNPSRAFLLAVNSLLLS Sorma SKILGDLKKSNL--SITNRLKSIQHDAAFV-Q-PLVA-NER----------------------------------------------------------------------------------------------------------------------------------------SRG--YIQGAGDDTENWAGLTAPLFWA--NQSRLLEPEGHLPGIEELVANSE-----K-SKTAVVLLCESGRDLSV--GVALALYHNKPSIRVKLGHIMTAFPDANPSRATLQSVNSFLMD Sphar ----QNLRSERL--SLFNRTRSIAKDSAFV-S-PLVA-NLRCGLWYSN---HAYFKSTDGHSHMCDLNMRRLNLHLLKHLQTGGFMLVDSSRR-KRF-PDSMSRTVPIWAACVNAVVLYVLPTMVSAMEKAQLE-SMME--------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 QKQREAIRKESR--NIYNRLRSIAEDSAFV-A-PLIA-NERCGSWYLD-PDSVYFKSTDGHFGKWDFNLRRLNFHILSDICKKGCIIVDSTRNGKRI-PDSLSKTIPIWCAVLNAAVLCTLPSVVSRSEHDQMA-LRIPVKKLMASADIASLSESLKPLRPLWITPATFYPVILLSASQGYTYVQGSADDHEMWGGLDPSIFWE--NAEEILANTTECEQVSSILASRNVINCGE-GKKGILFHCMQGKDRSV--GMALAVLVTKEIVHNRLLFIQSHRHVASPTRATMQKVKSYFMC Sporo1 QSDRGAIRGQLR--DTYNRLQSIKADADFIRD-PVIP-NQRAGAWYVE-PTHAYFKSTDGHTNEHDFNLRRVNLALLPLVKEKGIILVDSTRRGKRF-PDALSKTIPLWCATLNAARLYTSPQAVGPSEHAQIA-KKIDATDLAASYDLT-ALKALRPLRPFFVSPA-CYPIICASASKGFTYVQGSGDDHEAWSGLTPKLFWE--HADEILASREEIDTISKILDETSISVAAP-GKAGVDIFVRPANDLGI--AVALILLISKDLIRSRLQWILEAFPSINPSRAVLNRVNEFLMR Stehi1 ----EYLRKESL--DIYNRIHSIQEDIAFV-E-TFLP-NLRCGAWYTN-PAPAYFKSTDGHYNNWGFNLRRPNLHLITVASRNGLILVDSTRAGKRI-PDALSKTVPIWCAVINRAILYTPPGVISPQEHMQIE-GRLDAEELAASYTLP----DIYPLRPLWITPATYIPIICVSASRGFSYVQGSGDDHELWGGLTPDLFWK--HGSTLLDSRQDLEGVRRIVTEA-ILVCSS-GKKGVCIACESGKDASV--GVAVAAL--KQSIRRRLEWIIASRPQANPSRTTLKRVNDFLLS Tapde11 --------------------------------------------------------------------------------------MLDK---------------------------LHTPLQMVSKVEKHQIT-AQLQVHSLLATVDRD-ILAQLKPLRPIWITPESFYPLILVTASRGFVYVQGAADDEEMWSGLKPESFWA--APEQYLHDPASFGQLRNISEDANIAQLND-GKRGLLITDDQCQTKAA--VIALLILINKDIVKNRLVTLVNCRPGLNPSRAALKSLNEYLMS Thetr STTLRRLHSADH--SLAARILSIAADADWV-A-PVFA-NLRCGAWYA--PQTCYFKSTDGHTGQWAFSLRRLNAHVA-IEAAGAALIVDATRRGKPL-PDALSKTVPLWAAVLNRAALHTPPA-IPASEAHDMAACVAPADALAAAD-LSQLTTALKPLRVLWV-AQTFIPIICVSASATYTFIQGAADDEELW--------------------AESFHAIATLFAAP-VVNVSV-GKKHLLFHCPDGHDRSA--AAALAALVSKTTIRDTYVELTQLFPSARVARAHMKQVNRAFT- Treme1 ----KDVKKQTAKYDLYHRIHSIATDCEFV-N-EIIP-NQRCGNWYCD-PSHAYFKSTDGHNNNWQFNLRRSNLSLAEYAERGGIILVDSTRRGKRM-PDALSKTVPIWCAVINLVVLYTPPNIVSSSEKSQIE-VLIPAEKLLDSLIIP----QLRPLRPFFLHPATWTSIICLSASRGFEYVQGAGDDDELWAGLTPAIFYK--HKQVLLSDQDDLEKVFELVKNESLALDIS-PRSSDVMP--TDRRRII--PLALLALVDKSYIADMLYHLVSLWPDGNPPRAALKRVNEILMS Trire2 SSLLTQLRRSTL--TPRNRLQSIHADASFV-A-PLVA-NERCGSWYIP-PGSAYFKSTDGHERAWKFSTRRLNLHLIDMIEKDGIIIVDST----RM-PDALSTTIPIWCTVLNLALL--PPY-LPASTHAQIT-ALIPLSSLKELLNLPT---SLKPLRPLWITQDSYRPVICCTASRG--YIQGAGDDTENWAGLTPDVFWS--NADALLSSDAELPEIPKLVQEAK-----K-HKTAIVVACDSGRDLSV--GVALALSFTKTLVKMRLGAVMTAYPEANPSRNTLQSVNSFLMD Umbra1 MKHSEQIRQDHK--NVYNRLKSIEEDAAFV-H-AIVA-NERCGSWYIEPQPSAYFKSTDGHTGEWKFNLRRLNLHLIDVIAAGGCIIVDSTRRGKRL-PDALSKTIPIWCAVLNRAILHTLPSIISRSEHAQIA-VLIDADNLLRTIDLAEIRKKLKPLRPLWYTPQSFFPVICLSASQGYMYVQGSGDDEEAWSGLTAPMFWR--HRKELFSGAATCEQAMQIAARSKVINCTS-GKRGILVHCIEGKDRAV--GIALALLVDKIYIQQHLINIMNSRPQAKPSRATLKKINTYFMS Ustma22 WKHSDRIKRESR--HIYNKLHSISHDSAFV-H-LLIA-NLRCGAWYTD-PT-SYFKSTDGHTHQWSFSLKRSNLHLVPAIAHGGAIVVDSTRRGKSM-PDALSKTIPIWCAVLNKASLHTPQWLIPPTEHDQIL-AKIDVTSLLDSLEVP----QLKPLKPIFITPQTFTPIILVSTSKKFIYVQGAGDDHENWAGLTPEAFWK--HRTQLLADKESLEAVDTIVAEEA-----P-NKKGVLICCQDGKNLSG--SLAVAILISKDTTKRRLQWLVSANPRAAPSRAFLLRVNELLIS Walse1 --------------DEDN------SDSQFV-D-SVVAANQRCGVWYIN-PKYAYFKSTDGHTNAWSFSLRRPNLHLIEHILEKGLIIVDSTRRGKRF-PDALSKTIPIWCAVVSSAVLYTPPNAISESEKQAIK-DGLPREWLVNSLQLN---KRLKPLRPIFIHPETFYPILCVSASRG-EYVQGSGDDHELWAGLTPEAFWE--NQDELLSSSEMLNEIVEIMSERQ-----K-SSKQVAICDANGTDLAS--VVCVAIAITKTAINMRLQWLINVYPSSNPSRVSLKRLNDYLM- Zygro1 NQINRDIKKEYT--SLRNRIQSILFDNAFIAQ-PLIP-NERCGLWYCD-PKTSYFKSTDGHTNQWDFSTRRLNLHLLPILQENGIIIVDSTRRGKLM-PDALSKTIPIWCAVLNSLMLFTPPKCVSQSEHDSIK-TRIPVDRLEKLLDAQDLRNKFKILRPFWVYPGSIPIILC-----GFTYVQGAADDHELWSGLDPKLLWN--NWHYFHDNDKELESVKTLIELAEVIILSSGSKRSIMVCCNSGTDISV--GVILMILVNKFVIRRHLVQIINKIKNVNPSRATLNSINSFLM- [Cluster2852.fasta_al_trimmed; alignment length = 79] Allma1 TNPQVALLSDFEVYQFMSELMYLRREVAYYFEVVAFMRAIQLYKGEKLRLLNVRPKNLVALLLCVDEADERYAEMLRIL Ashgo11 EATRDAFISDYEALQFMSHLQAITKDVVNYLTFTTLMRTLNLYKAEKLQLVNQLPVNIVHLYALVEECDSRFSAIIDAI Aspfu1 ------------------------------------------------------------------------------- Aurde31 --------------------------AIQYLSTRALLGALRLTKGEKLQIVNLAPTEPVELYVVVEELEERL------- Batde5 VQINSALLCDSEVLNFLQELHTVEYEVVTYLSVNSFLEAIKLTKAEKLQLLNLRPVSAIELSAIIEECEIRFTELLQIL Botbo1 LNARAAMLSNYEVLTLLSEWRTVEYETLKWLKIARLAKDLRLTKAEKLQIINLMPVDQAALYPIIEDFEDRFEEINRCV Botci1 LEAQSATLSNFEVYTHLKDLDNVIKELMQYLEIRNLLEQLRLPKAEILMIINHRPTSMENLNIIIEELELRFWGIIDVV Caeel LKTRETMLTNQEVLSFLNALSTVIYETKKYLNICELIPKLALTGAETLQVINLRPSTTADIQLLIEETEERFEKLVSTV Canalb1 LTERDSFLSNYEVLQHLQNLEIITRDVLSCLEFKQLMEFLNLMKVEKLQIVNSLPRSLVVLYALVEECEDRFESIIEKI Cangl LETRDAFLSDYEVLQHLSKLQRITRDVIDYLKFTELVMRLNLFQAEKLQIVNQLPVQMVHLYAIVEECDTRFDALLQLV Capow LEPITALLSNYEVYTIVSALHTIAYEVRQYLAIEAFVKAVQLTKGEILQLINLRPATLPAMTPLVEEIEERLNQLLELI Catan2 VNPQVALLSNYEVFTLLKAGTEIERQVFSYMTFTSFLERIALLKGEQLMLLNNRPSSMTGLFTCIEEIDERFEEMLAII Cioin ----------MEVLNILNELSTITYETIKYLSIETTLKALLLTKAEKLQLVNLRPTTAVEISLIVEESEERIDEIIEIV CocheC53 ------------------------------------------------------------------------------- Coere1 VDRQAALISNYEALLVLREVTTLMFEALEYLNIIALKQQLGLTKAEIMQIINHRPKSLVELHLIVEECDERFERIVETI Conco1 IEERSSFLSNYEVLSLLKEQLILTEQAIKYMEFLKIMQKLKLVKIEKLQILNILPNSAPLYSPIIENLMERFEDLIDQL Conpu1 IKARSAFLSNYEVLTLLRELRTIELEGIQYLSIQRLVNNLALTKAEKLQIVNLAPTEPVELYVIVEELEDRLEDILGAV Copci VNARAALLSNYEVLSLLKELRTIEVEAIQYLSITNLVKKLELTKAEKLQIVNLVPTAAVELYVIVEELEDRFDALLATI Croqu1 INPCLAHLSAYETLELIRSIQELIYPFIQHFEIESLLEALRLTKAERLQICDLAPTEAVDIYLIIEECDLRFEAILSHI CryneH991 ------------------------------------------------------------------------------- Crypa2 LESQNAVLTNFEVYQHLLNVQTIVKEVLEYLKINRLVDRLHLTKGEMIMILNVRPENLAILSSCIEDFMTRFQEIQTII Debha1 LEERDKFLCNFEVAEHLNSLEEITRDLSSYLEFKELMIHLNLMKVEKLQIVNSLPRSMVHLYALVEECDQRFEGIINKI Dekbr2 EVPRDKLLSNYEVYQHLAKLEIITKDLSRYLVVINLVLGLNLEMIEKLQILNILPRSMVLLYAIIEDCDQRFEDLLSLV Dicdi KKDKEEIITNFEVLQLLKHLNEFVNNVIRYLEVKE----CKILTGEMLQILNIAPSSEVEVHLVIEDCEDRIKEVLKEI Dmel ------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------- Falba LELPTAYLSDFEVLQAILQLMQVEADVKAHLHIAAFLEAAILTKSEKLQILNHQPRSLVELHVLLQEAEERFGQILAMI Fomme1 VAPRTALLSNYEVLTLLKELRTVEVEAIQYLTITQLVRGLNLTKAEKLQIVNLAPTEPVELYVIVEEIEDRFEDVLQVV Fusgr1 LEAQSAVLTNYEVYEHLTELETVVRELLQYIRISQLLQRLRLAKGEVVMIINLRPASVAALNTVVEEMTERFEAMVNII Galma1 INPCAALLSNQEVLTLLRELRTIEVEAIGYLSIAKLVQDLGLTKAEKLQIVNLAPKLPVELYVIIEELEDRIDEILGHV Ganpr1 VDEQSARLCDSEVLALVRELATVEHQLISYFKVQALQVALKLKRNELLQIVNTRPTLPVELAIVLSNPDS--EDMLAAI Gloin1 IEKRNAQLSNHEVLALLRELKTIQFEVIQNLTIESVLFELKLTKSEKLQIINLRPQSIAELELIIEDCEDRFREMIYMI Hisca1 ------------------------------------------------------------------------------- Klula1 LEEKNAFMSDYETLQFLISLQTITRDTVRYITFSTLMQELNLYKAEKLQIVNQLPTNLVHLYSIVEECESRLTSLLECI Lacbi2 VNPRVALLSNLEVLTLLRELRTIEVEAIGYLSVTKLVKDLALTKAEKLQVVNLAPTLAVELYVIVEELEDRLEEILTHV Lenti61 LNQRSALLSNFEVLTLLRELRTVEVEAIQYLSIAQLTRNLALTKAEKLQIVNLAPTEPVELYVIVEELEDRFDDILSTV Malgl1 LKARAALLSDYEVLQLIRELRTMQFEMISALSIRAFLDDLNLTKTERLQLVNHAPSSVVELHTLVEELGQRMAEILQCV Mellp23 INPRLAHLSAFETLELIRAVQELIYPFVQHFEIADLLNALKLTKAERLQICDVGPSIAVEFYLIVEECDFRFDEILSIV Mnele VNPCAALLSNYEVYLILKELSTIAYETLKYFEIPDFVRSVKLSKSELVQLINMRPTTHVELHAIIEECEDRYAALLDVI Monbr ------------------------------------------------------------------------------- Morel2 LQTNSAMLSNYEVMALLADLRTVEFEVQKYLAIRELKKAFKLMKVELLQILNLRPKSAVELLLVIEEFEERFDKMLSII Mucci2 KSVRSALITNYEVLRLLEELRTVQFELTEYLKISNFMKAISLTKAEKLQILNLRPKSTVEIYLLIEECEERFEQMLSSI Mydma ------------------------------------------------------------------------------- Neucr2 LEGQSNLVSNHEVYEHILEQFTLTKDLLTYLRLYELFKKLRLSKGEMLMIINLRPTNVAVLSTVVEDMLERFQKIIDII Orpsp11 --------------------------------IENVINALKLTMTEVFQLINLRPKALIDLTLIIEECESRFEDLLTII Pench1 ------------------------------------------------------------------------------- Phybl2 TNACAALLSNYEVMALLDELRTIQFEVTEYLKLKDFLDALKLTRAERLQILNLRPKSAVEIYLIIEECEERFENMLNII Picst3 LKERDSFLSNYEVAEHLKELEVITRDILSYVSFSELVQFLNLMKVEKLQIVNSLPRSMVTLYSIVEECDQRFNNILEKI Plicr1 VNARSALLSNFEVLDLLRELRTIEVEAIQYLAISQLVKDLELTKAEKLQVVNLAPVEAVELYVIVEELEDRLDDILTHV Polpo SNKYDELITNYEVLNLLKHLNEFVSSVVGYLEVKETKELCKLTKAETLQIINLAPTTEVEIHLIVEEAVERLVAFTDDV Pucgr2 LNPNLIPLSAFETLELVRELDQLVKNILTHFEILSLCESLRLTKAERLQICDLAPTELVEIYLIIEECDSRFQEIIDLV Punst1 INPRAALLSNFEVLGLLKELRTIQVEAIQYLDITTLLKGLALTKAEKLQMANLAPTTAVELYTVVEELEDRLNEVLELV Rhior3 KNARSALISNYEVLKLLEELRTVQFELTEYLKIADFMQAISLTKAEKLQMLNLRPKSAVEIYLIIEECEERFENMLNTI Rhoto1 LNERAGFLCNHEVLQILRDLHTVTFEALRYLEVSKLLDELELTKAERLQLVNLAPTTAVELHVCIEDVTERFERLLQLV Rozal11 LHDRVVFLSDAEVYDHL-----------KYVSILRINETLKLTPAEKLQIFNMLPTSMVELICIIEECEERFQEIIDAI Sacce1 LEERNAFLSDYEVLKFLTDLQGITRNVVNYLSFAELMTKLNLFKAEKLQIVNQLPANMVHLYSIVEECDARFEEMLEII Salro VEGSHRLVSNKEVLNLVEDLRTITFEVKQYLSITNFLERTKLTKGEKLQILNMCPRHELGLNLIVEHCPQRFRELLETI Schco3 VKARSALLSNYEVLSLLQELRTIEVETIQYLSISKLIKSLELTKAEKLQIVNLAPTNIIELYVIVEELEDRLEEVLARV Schpo1 LEARDAYLTNAEVFFHLKELRTIQFEILKYLSFLDCIAIFNLTKAEILVILNNKPSSVPELYACIEGIEERFFKLVEKI Sorma LEGQSNLISNHEVYEHILEQFTLTKDLLTYLRLYELFKKLRLSKGEMLMIVNLRPTNIAVLSTVVEDMLERFQKIIEII Sphar IEAEHALLTNWEVSEVIKNVATLCYALQNYFKIQKLTKGMALTKAEKLQIVNNMPRSEVEIHVIVEEVEERLEEIVSAV Spipu1 LELRAAHLSNFEVLTFLSELHTIEQEVIKYLKVQQFKEALQITKAEKLMLLNIRPRSIAELNPLIEDIDDRLEDLVGLI Sporo1 ------------------------------------------------------------------------------- Stehi1 LNPRAALLSNFEVLSLLRELRTVEVEAIQYLSIAQLTKSLELNKSEKLQIVNLAPVETVELYVIVEEMEDRLDEVLSHV Tapde11 VEVRSAFLTNFEVSKHLEALRTVQFELKNYLDLVAFLKEIKLTKAEKLMILNQIPGNEAEISVLLEEYSDRFEDLLEVI Thetr ------------------------------------------------------------------------------- Treme1 ------------------------------------------------------------------------------- Trire2 LEAQAAVLTNYEVLQHLTQLETVVRELIQYLQISRLLERLSLSKGEVVMILNLRPASVAALNTVIEEMAERFEEMVAII Umbra1 IESRAALLSNFEVLQLLNELRTIQFEIKTALEVVAFLEEMKLTKAEKLQILNLRPQTPVELHILIEECEERYDDILEVV Ustma22 LKARSALLSDFEVLKVLKELRTIQYETISSLSIVAFLDELKLNRSERLQIVNHAPQSVVELHTLVEELEERFEELIALV Walse1 LNARVGHLSNFEVFEIIKE--------VKYLSITNLLQSLELTRAEKLMIVNLSPKSVVELYVIIEELEDRLEAILSLV Zygro1 FETRDAFLSDYEVLQFLSKLQSITRDTIAYLKFSELVRNLNLFKAEKLQIVNQLPQSMVHLYSVVEECDSRFETMLSTI [Cluster2855.fasta_al_trimmed; alignment length = 152] Allma1 RVGQLDASLLDAQLMFKDQLTDALTLLGILVPL-LALGYGLSLQNLRYPRIAAHAVLA--AVDRAMSKATVISLVTLVRFLVTGRYRTPLERVMGLRVVLAFLHRQILWNAFT--EFLLFALPLYRRIRRVLLRYCYYCAQVKHCVRCGKGV Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 RVGQVDAELLDEELLLKGQVGNALFALRAILFK-LSISYGAALQGLRYWQKSLYGLLT--VLARLTGLVSIAAFVSFLVFLVNGRYRTLVDRILRIRLTFEYLNRQLVWHAFT--EFLLFLLPLVGRWRRWLSRYCFVCLVQKVCLRCGEIV Aurde31 RVGQLDADQLDQDLMLKEPFAKALLIIHAILYK-YSVTHGARLQGLRFRTVYAHAFLT--VLWDVMTLAGALALAGFCVFLRNGRYRTLVDRILGLRLVYEFMNRQMVWHAFT--EFLLFLLPLVNILRRRLMAYCYFCLAQSLCLRCGELV Batde5 RSSQLDADLLNNELLLSEQVTSIFAILEWLISE-STLTYALQLQNLVYFQKTMHAILN--IIWKLIQRLKIVSVANFLVFLYSGRYRSLLDRLLGMRVVFEFMNRQLVWHTFT--EFLLFIIPFINAVKRALQKFCYYCIKTEMCPRCGVTV Botbo1 RVGQLDAEQLDQELLLTEPLSKALLIVRLVLYK-LSISYGAKLQDLRYVTLYMHAFLT--VAWEFLTRLSVLGLFGFISFLYNGRYRTIADRLLGLRLVYEFMNRQMVWHAFT--EFLLFLLPLVNVLRRRLVRYCYMCLSERMCLRCAKIV Botci1 RVGQVDAELLDEEMYDEGQVGEGLLALRAILSN-LSITYGATLQNLKFWQKSLYGLFT--VLSRITDLLSTAAFASFLVFLVNGRYRTLLDRILRLRLAFEYLNRQLVWHAFT--EFLLFVLPLVGRWRRLLSRYCFVCIASKLCLRCGEDV Caeel RVDQLDAHVLDSEIIAQDSVDDVVVTLEAVL------SPGQEQMDIAYKLITSHFMVE--VISRMYSKIELGSLLHFLYFLRSGGHSTITESIFSLRNWYDTQNRELMWHAFR--DVILLTYPFIEKLDRKFTSACYTCIATS-CPLCSEN- Canalb1 RVSQLDAGILDSELLLKEQLSSIFLLLNLLIFR-LTVSYGSSLQNLKLSRKALLGAVI--IRTSILSGLKIANLVNFTFFLVNGQYSSLVNRILGIIETYEFQNRQLVWNVMT--EFLVFILPLLQKLGRMTRKYCYVCISTRFCLRCGKRL Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------- Capow --------------LMRGQFLKLFALVHLMIYR-LSVTYGQGLLSLKYWQKVLYGLAY--ILWRLKENLKFLTVLNTILFLRDGRFPFLIDRILRIRQVYEFMNRQLLWHGFA--EFLLFLLPLINKIKNVALRYCYVCIASNCCLRCNAPV Catan2 RVGQLDADQLDTQILLKDQLANAMAALHAILLG-LSLTYGMYLNQFTYGKLWLFALLS--VV--AATRINSLVLLNLLRFLVTGRYPTPLHRLLKLQPLFAFLHRQVMWAALT--EAILFALPLYHLVRRWI--------------RPG--- Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RVGQVDAELLDEELLLKDQVGEGLLLLRAVLWK-LSISYGAHLQGLRYWQKIAYGAIT--VLGRLSELADVLGLASFLVFLVDGRYRTITDRLLRLRLTFEYLNRQLVWHAFT--EFLLFLLPLVGRWRRILSRYCFACLAQRICLRCGENI Coere1 ---------------------------------------------------------------------------------------------------FEFLNRQLVWHAFT--EFVMFALPLVNRARAWVVRYCYVCIQSRMCLRCGDKV Conco1 RVSQLDSQLLDKELLLKDQFWQSFLILKSLCFY-FSMSYGNKLQNLKFKKILAFYLLS--IVLIGLQKFKYASFLNYCAFLVDGKYLTLVGRVLRMRLIYEFLNRQLIWDAFS--EFLMFLIPLINKLQTNFRKFCYACISTNLCIVCDQRV Conpu1 RVGQLDAELLDAELLLQEPLNKALLIIQLTLYK-LSVSYGAKLQGLKYRLLLLHGTLT--IAWDFLTRLALLGLGNFIAFLWNGRYRTLSDRLLHMSLEYEFMNRQMVWHAFT--EFLLFLLPLVNALQKRWSRYCYHCIAERMCLRCMEPV Copci RVGQLDSELLDQELLLQEPVSKALLFIQLVLYK-FSVSYGAKLQDLHYRTLAIHALLT--LAWNLLELLASLSLANFTLFLWNGRYRTLADRLLSMRLVYEFMNRQMVWHAFT--EFLLFFLPLIDTVRKRFYRYCYHCIAERMCLRCCEIV Croqu1 RVNQLDAELLDQELGLQFNLSNALLILRSLILF-LSLSYGSQLQNLRWTQIKAYILLD--IAWDLSTILSSCKLAHFLIFLYDGRYRSILERFLGIRLVFEFLNRQLVWESIT--DFLLFILPFINRLKLRLLQYCYHCLVSEICWRCGNVV CryneH991 KVNQLDADELDDALMLGEKVLRSILVIKLVIFR-LGISPGAKLQNLKLSALLLYLLFHPPIAWKALGRIKIWEAFGWAGFLWDGKYPSLLMRLLGLRMVYEFMNRQLVWSAFT--EFLMFAIPLLPPPSLRLSPWCYYCIGEELCLRCGDGV Crypa2 RVGQVDAELLDEELLLQEQVGDALLVLRAVLFK-LTVTYGAALQNLRYVQKTLYGLVT--VLRRLTSAAAGAAFVSFLVFLLHGRYRTLLDRILRMRLAFEYLNRQLVWHAFT--EFLLFVLPLIGKWRRWLTRYCFVCLATRICLRCGEVA Debha1 RVSQLDANILDSELLLKEQLTSIFLLLNLMVFR-LTVSYGALLQNLKLSKRTLLCAVL--VKTKILLGLKLLNLVNFTLFLVNGRYPSISHRLFGISLTFEFQNRQLVWNVMT--EFLVFILPLMQKLKRMTKKYCYICIATKFCLRCGMKL Dekbr2 KVLQLDALSLDIELTLNSKLSVAFSILKLFLFK-STITYGLRLQNLTLLRKL--SLLS-SILGKLVRQLAIFSLANFVTFLLNGKFPSLMDRILKVSYIYEFQDRQLVWNTST--EFLAFTLPLISKLLISLKSYCYYCIINKLCLRCGMPV Dicdi RVSQLDSARLDEEILLRSQFMKIFLVLKSVIYK-LSITYGNQLQNLTYRQKWLSGLIN--IFWNFLNFAKALALLNFLTFLFNGKYVTLVNRILHMRLVFEYMNRLLVWHGFT--EFILFIMPLINRIKSFLYRFCYYCIKTSCCPRCNSLI Dmel RVNQIDAIYLNKDILIRDNLLENLLIIQSAIWF-GSVTFGQQLLVLAYSRLVLHFILT--VMW-----VLILNILNYFRFLKTGRKPTLVDYLLGLDYIYKYLTRELLWGGFM--EILGLVLPIINKLQRVLKSYCYYCLNANVCPNCGSAC Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------- Falba RVTQLDSIRSNTSLAVARMLDDLPLLLRLVPF--LPLSFGQQLLGLSFRRLLQFLVLH--AALQAVRITQLAQLVNFLGFLFGGRYPTLSSRITGLQLYFPWMHRDILWDAVG--TFAFFAGPYIPGLGRHAGRACYTCVGGAHCPRCATAI Fomme1 RVGQLDAELLDEELILQEPLTKAFLIIRLTLYK-FSMTYGAKLQDLRYRILASHALLT--VAWNIITQLSAAALLGFVVFLWNGRYRTLADRLLSLQLIYEFMNRQMVWHAFT--EFLLLFLPVFSAFRRTYNQYCYACLSEKLCLRCTELV Fusgr1 RVGQVDAELLDIELILKDQVSEGLLALRAVLFK-LTVTYGAALQNLKYVQKSLYGLVT--VLSKFTSAISAAACVSFLVFLLHGRYRTLLDRILRMRLAFEYLNRQLVWHAFT--EFLLFVLPLIGRWRRWLTRYCFVCLATRLCLRCGEHV Galma1 RVGQLDSELLDQELLLQEPITRALLLIQLTLYK-LSISYGAKLQDLRYNTLLMHGTLT--LIWDSLGSAGLLGLANFVAFLWGGRYRTLADRLLRMSLVYEFMNRQMVWHAFT--EFLLFLLPLISVIRRRFYRYCYHCIAERVCLRCGEEV Ganpr1 RVNQVDAELLDNDLSLNERLVSLIALFHATIYW-FSISYGSQMQNLKYTQKALHASLT--IVWRWIQRARAATVVNFVVFLYDGKYRTLIDRLLGMRLVFEFMNRQLLWTALT--EFILFIMPLINRLRATLSR----XLRPRV-------- Gloin1 RVSQLDADLLDSELTFKEQLW---AILHF-IYR-LTVTYGAQLQNLKYFQKFAYIAMT--VFWKVLQKVKTVSLLNFLIFLYDGKYSTLTDRILSIRLVFEFLNRQLVWHAFT--EFLLFIMPLINKLKNLLKRYCYFCIKTKLCLRCGAEV Hisca1 RVGQVDAELLDEELLLKGQVGEGLFALRAILFK-LSVSYGAALQNLKYWQKSLYGIFT--VLSRVTKVISIAGFISFLVFLTNGRYRTLIDRVLRMRLAFEYLNRQLVWHAFT--EFLLFLLPLVGRWRRWVSRYCFVCIAEKLCLRCGDLV Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 RVGQLDSELLDQQLLLQEPINKALLLIQLTLYK-LSVSYGAKLQDLKFRTLLNHIFLT--LAWNVLNLLTLFGLVNFVAFLWGGQYRTLADRFLKMKLVYEFMNRQMVWHAFT--EFLLFLLPLLNSIRRRFYRYCYHCIAERMCIRCGADV Lenti61 RVGKVDAELLDTELLLKEPLTKALLLIHLVLYK-FSVSYGAKLQGLRYPTLVLHSILT--IAWESLTRLGLAALINFIVFLWNGRYRTLADRLLRLRLIYEFMNRQMVWHAFT--EFLLFLLPLINAIRRQLTSYCYYCLTERMCLRCAEGV Malgl1 RVGQLDSHLLDQELLLTQPVKNALVALRLILYK-FSITYGAMLQNLKYVQLALHPLLT--IAYSLSEHWSLIGLVNFSLFLWNGKYRTVADRLLGMRLTFEFLNRQLVWNAVM--EFLLFIVPLVRHLFHLLTLYCYSCIGRKFCLRCGDII Mellp23 RVNQIHSSLLDQELTLIPSIHQITTFLKFYWIS-TSLTFGSKLSNLK-HQLSIYIILK--IIWDTYNLLSSAKFINFSIFLYNGQYRSLMERLLKIQWVFEYLNRQLVWESIT--DFIIFILPFINRTKLRILQYCYSCLINSICWRCGEIV Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KVSQLDADLLDEELTMKEQLWSAFLALNLIMYK-FSVTYGSQLQNLIYTQKITYGVVT--VAWNVLQKGRIVSLFNFLAFLYAGKYRTVLERVLSMRLVFEFLNRQMVWHAFT--EFLMFLMPLINKLKRNVKRYCYYCIKTKMCLRCGKKV Mucci2 RVSQLDSDILDIELILKEQLWSALAILNLVLFK-LSITYGAQLQNLKYTQKILYGLFT--VVYRVLQTGKAFSLINFLVFLWNGRYRTLIDRVLAMRLVFEFLNRQMVWHAFT--EFLLFLVPLINKLKMKLMRYCYYCIQSKLCLRCGEKV Mydma RVTQLDADYLTNQAIIKREIKGSLVLLQFIIWK-YSLTVGQLYFKMKYRQKLFYFFLN---ITLIVSKLQLAEFVNYVLFIKNGEYLNLLDRLFNWKTIYTYMRKELLWSKIT--ETIFCVLPFINKLYNFFMLFCWYCIKGNLCPTCGKNI Neucr2 RVGQVDAELLDAELLLRTQVGDALLILRAILFK-LTITYGAALQNLRYLQKSLYGFVT--VLSRLTESIAFASFASFLVFLLHGRYRTILDRLLRMRLAFEYLNRQLVWHAFT--EFLLFVLPLVGRWRRWLARYCFVCVATRICLRCGELV Orpsp11 RSCQLDSIIIDKEIILRELFLKIFFLVNLLIYR-FSVTYGCKLQNLKYEQKLMYFILK--VIWKLFQSLKLSSLLNFYVFLYNGKYTSIVDRLLKIRLVNDYLSFQLVWSVLT--------------------------------------- Pench1 RVGQVDAELLDEELLLKGQVGDALFALRAILFK-LSISYGAALQGLKYWQKGIYGLLT--VLSGLTDILSIAAFVSFLVFLVNGRYRTLVDRILRIRLAFEYLNRQLVWHAFT--EFLLFLLPLVGRWRRWIARYCFVCIVQKICLRCGEVV Phybl2 RVSQLDSDILDSELILKEQLWNALALLNLALFK-LSITYGAQLQNLKYTQKIIYGVLS--VIYRVLQAGKALSLVNFLVFLYSGKYRTLLDRILGMRLVFEFLNRQMVWHAFT--EFLLFLVPLINKLKLRVTRYCYYCIQTKVCLRCGEKV Picst3 RVSQLDAHILDSELLLKEQLASIFLLLNVLVFK-LTVSYGLALQNLKLSKRSLLLALL--VRTALISSVKTLNLINFMLFLVNGKYPSLIHRALRITMTFEFQNRQLVWNVMT--EFLVFLLPLLQKLRKMARQYCYVCISTRFCLRCGLKL Plicr1 RVGQLDSELLDQELLLQEPLTKSLLLIQLILYK-LSISYGAKLQDLRYRTLLIHGALT--VIWDTLTALSLLTLLSFIAFLWNGRYRTITDRILRMSLVYEFMNRQMVWHAFT--EFLLFLLPLVSGVRRRFARYCYHCIAERMCLRCTAGV Polpo RVSQLDSTKLDEEILLKAQFMRIFLILKSVIYK-LSITYGNQLQNLTYKQKWLSGIIL--ILWKLLNQLKILSLVNFLAFLFDGKYVTLVNRLLCMRLVFEYMNRQLVWHGFT--------------IKGFLYRFCYYCIKTSMCPRCNSLI Pucgr2 RVNQLDAGLLDDELLLLAPLSTSLMLGQLLILG-SSLTYGSRLENLQWRKMALYILLS--VVWEGVERLRLLGLLNFLAFLVKGSFRSPLERLLRIRLVFEFLNRQLLWQALTVSDFILFILPLIDRLRLRLRAYCYSCLLHDICWRCGDAP Punst1 RVGQLDAELLDQELVLQQPLANALLLLHLVLYK-LSVSYGAKLQGLRYRTRLAHGALT--VAWDALSRAALLALVNFVGFLWNGRYRTLADRLLRLRLVYEFMNRQMVWHAFT--EFLLFLLPLINLVRRRLTR----------------PI Rhior3 RVGQLDSEILDNELILKEQLWSAFALLNLTLFK-LSITYGAQLQNLKYAQKISYGILT--VIYKLLQYGKLFSLINFLVFLWNGKYRMLIDRLLSMRLVFEFLNRQMVWHAFT--------------------------------------- Rhoto1 RVSQLDASLLDNELILHGPVKTALALLRLAVLK-LSLTYGSALQNLRYIQKLAYTLLV--VGWELLNVGAVLGLVNFLVFLYNGRYRTLIDRVLKMRLVFEFLNRQLVWEAFT--EFLLFLLPLVNRLRLRVVKYCYYCVVGALCLRCGGDV Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ----------------------------------GSLTYGQTLAGIR-RRLLLRPILT--ALLRLLTNAEVLSTLNHFVFLYSADFPTLPDRLLRL---LGYLQQEML------IQVLLVALRRVASLPAWLTAICFSCAVIAFCKLCGAPC Schco3 RVGKLDSELLDQELLLEEPLKKALLLIQLTLYK-LSISYGARLQDLRYRLLLLHGAAT--LLWELLTSLAAFSLANFVAFLWNGRYRTIADRLCKLELTYEFMNRQMVWHAFT--EFLLFFLPLINAVRRRLSSYCYHCLAERLCLRCGQGV Schpo1 --------MIESELIATQTTRSLT---ESVLHF-LELLLGRKRLSA--RKIVRFLNVI--IINGLQSYLELGSF-----------QELSTSSLGSFRMFFCTRIPASLWIKYK--EYT--------------TSYCYACIMSRLCPICKHRI Sorma RVGQVDAELLDAELLLRTQVGDALLILRAILFK-LTITYGAALQNLRYLQKSLYGFVT--VLSRLTESLAFASFASFLVFLLHGRYRTILDRLLRMRLAFEYLNRQLVWHAFT--EFLLFVLPLVGRWRRWLARYCFVCLATRICLRCGELV Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 RVSQLDAELLDAELVVKEQFLAIFALLQYLMCH-LSISYGLQLQNLKYWQKMAHALLY--IVWTYLQKARALSLVNFLVFLYNGRYRSLLDRVLRMRLVFEFMNRQLVWHAFT--EFLLFLVPLVNRIKNTIIRYCYYCIKTSICPRCGQKV Sporo1 ----TDSSV--------GTV----------------------------VQKVLYTALF--VLTELLRLGQIAGLLNFLVFLYNGRYRSLVDRVLKMRLVFEYLNRQLVWEAFT-----VCLLPLL--------------------------- Stehi1 RVGQLDAELLDQELLLQDPLTKALLLIQLTLYK-LSVSYGARLQELKYPILAIHGALT--IAWELLTGVAFFSLLSFVAFLWDGRYRTLVDRLLGLRLAYEFMNRQMVWHAFT--EFLLFILPLLPTMRRVVSTYCYVCISDKMCLRCREAV Tapde11 RVSQLDSHQLDQELLLSANLEASLVCLRAVIWK-LGITYGAQLQSLRYAKKLLLGFVS--I--------EVLALANFISYIAGARYDSVLHRVLKIQLRFEFLNRQLIWSQFT--EFLLVFLPLLHRLR-----YCYGCIVSQLCLRCGRRV Thetr RAGAADSYVFNSSLVYRPRIVDALAALALLLHH-ASLTFGGLLYNMVYPRKLLHVAAS--TGGAILRTVRAASLVNALVFLRSGAYVSLLDRVLGMQLVLHFMDRTLGWIALS--NALAALLPLINRVKTALDYGCYYCLAAHRCPRCASGV Treme1 RVSQIDSDELDEGLMLGERVHQGLLVLKLVIFR-YGISPGSKLQNLRLRTLLLYLLLHPPIAWRMLVRVRAWELLGWGMFLWDGRYPSLLMRILGLRLVYEFMNRQLVWGALT--EFLMFSVPLFPP--TFLTPWCYYCIADELCLRCGGAV Trire2 RVAQVDAELLDEELLLKGQVGDALLALRAILFK-LTVTYGAALQNLKYLQKSLYGLVT--VLSRLTSGLSAAACVSFLVFLFRGQYRTVLDRVLRMRLAFEYLNRQLVWHAFT--EFLLFVLPLIGRWRRWLSRYCFVCIATRLCLRCGEHV Umbra1 RVSQLDSDLLDVELMLKEQLWSAFAILSFLLYK-FSISYGAQLQNLKYTQKILYGLFM--VVYNILQRAQALTLVNFLVFLFNGRFRTLIDRILQMRLVFEFLNRQLVWHAFT--EFLLFLMPLINKLKLKVSRYCYVCLKSKICLRCGERV Ustma22 -------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 RVQRLDGLELDDEVRITQPIIDALAIKGVYMWKYLNIIYGMGLQLLKYTKSILYLISR--IVVRIVDRLDIANIGNHISFISGGNFANLTERALSLNVSLEFTQRQLVWSVMT--EFL----------------YDYSCLINLICSVCKSKI Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2865.fasta_al_trimmed; alignment length = 50] Allma1 FCRSAFAIVAGITAGILGLTGGFGFFVVATLVLSALLTVA-RYFGGVFTY Ashgo11 YVHDITSLVFGCGAGILQLESGFIMFAVSYLSISAIFAMS-KYFRELAGF Aspfu1 -------------------------------------------------- Aurde31 TVKFYASCFAGAVAGILGLETGFAVFAVASLFAAGVLVGK-AYFDNLMSF Batde5 HTRSSLALFSGAAAGILGLQGGFLFYLAVSLFMSLLHFFE-VYLANLSSY Botbo1 NIKFLTSCFIGAVCGILGLENGFALLVVWTMVTSGVVYVK-KYVDNLFSF Botci1 TLHNLTASLFGVAAGILGLESGFLFYIFFTLLTSALVYVD-RYFEGLSGF Caeel FGRTCQSCAAGMAAGILGLTGGFILYFISVGIQA-VIWNL-SYFNGLLTF Canalb1 HVHDVASLALGVGSGILTLESGFIFYLIGITVTNLLFYIS-KYFSNIPGF Cangl YVQDSTSLVFGLAAGILQLESGFLAFLGCYTTVCLIFILQ-KFFRELTGF Capow RIRTGAAVISGSTAGILGLTGGFGFYFVASLLLS-LLLFA-AHFDGLSTY Catan2 FLRSTFSAIVGSTAGILGLTGGFGFYIAASLFFSLLITLA-KYFSGLFSY Cioin -------------------------------------------------- CocheC53 NIRSLTASLFGVAAGTLGLESGFIFYLLASLVVSALLFAS-AYFGGLSGF Coere1 NIHTLTSWGVGTAAGILGLTGGFIFFLANWVVISALILFS-VHFNTLLSY Conco1 HLKSIFCILSGSTCGILGYTNGFIFYIVSAALLNLLLFVKVDYISDLPSF Conpu1 SVKFISSCFAGAVAGILGLENGFALFLASILSTSFVIYAA-KYLDNIFTF Copci NVKFLSACFAGAAAGILGLENGFALFLASTVLTSLCVGVG-KYVDNAFSF Croqu1 TIKSTTSSIAGALAGILGLKNGFIFYLLSSLLISTLIHL--ILFDNLFGY CryneH991 -------------------------------------------------- Crypa2 NLQSLTASLFGVAAGILGLESGFLFYIVFTLLTALLFYFS-RYFGGLAGF Debha1 HVHDIMALALGVGAGVLTLESGFLFYIIGFTITNLAFYRF-EFFSNVAGF Dekbr2 RLKDITSLSFGCCSGILQLTAGVFLFLIANLVSGVLFYFK-QYFRYFSSY Dicdi FCQIPISILGGAIAGVIGFSGGFLFYFFIYITFCSLFTLH-LYFAGLMPY Dmel YCRTSMAAISGCAAGILGLSGGFLFYFLSVFVLW-ILVLR-KFFGGLCTY Enthi -------------------------------------------------- Falba HLRTITSAGAGAVAGLLGLTGGLALLFAASLAMSLTIRISLAFFNTLITF Fomme1 SIKFLSSCFAGAVAGILGLENGFAFFAASTLLTAACMYVA-KYIDNVFSF Fusgr1 NLHSLTASLFGVTAGVLGLESGFLVYIVFSFITTLLFYVS-RFYNGISGF Galma1 TTKFLSACFAGAAAGILGLENGFILFLASTLLTAGIVHAK-KYFDNAFTF Ganpr1 QLRSSVAAVLGIAAGILNLTGGFAFYLVASVLVGGLILAD-VYFGNALSF Gloin1 FIRSSMSAITGSAAGILGLTGGFIFYTLTAILTSFLIWSG-VYFGGLFSY Hisca1 -------------------------------------------------- Klula1 RIQDSTMLTAGLSAGILQLQSGFGMFFAVYILVNLIFIAS-LYFRELAGF Lacbi2 TVKFLSACFAGAAAGILGLENGFTLFLTSTILTSVCIYTA-KFIDNVFTF Lenti61 TVKFLSSCFAGAVAGVLGLENGFALFIFSTLLTSSCLY-A-KFVENIFSF Malgl1 SFRSLALSIAGAVAGVLGLQNGFGFFAISVVFVNLVLIAE-KLVENLLSF Mellp23 FIKSMTSTISGSLCGILGLTNGFLFYLLTSFIVSSLIWFSLTYFDNLFTF Mnele -------------------------------------------------- Monbr -------------------------------------------------- Morel2 FIRSSYSAVLGLAAGTLGLTNGFIFYLLGSTFLSVLIFVG-LYFGGLFSY Mucci2 YIRSCFAAIAGSAAGILGLTNGFLFYALSWTILS--VLLS-KYFGGLLSY Mydma YCRAFLAVVSGSAAGILGLTGGFVFYILVSFLMS-VLLGE-RYFGELFTY Neucr2 NLQSLSASLFGISAGILGLESGFLFYIFFSLLTSFLIYLK-KYFNGFAGF Orpsp11 -------------------------------------------------- Pench1 -------------------------------------------------- Phybl2 FIRSCFAAIAGSAAGILGFTNGFLFYALGWSILSAFVVIS-RFFNGMLSY Picst3 HVHDIASLVLGVGSGVLTLESGFIFYVVGITLTNLLFYLH-KFFTNVAGY Plicr1 TVKFISSCFAGAVAGVLGLENGFALFIASTLLTSACIYAG-KYIDNMFTF Polpo FCQILIATVGGSVAGILGFSGGFIFYIFVHLVFCSLYNLQ-QYFSGLMSL Pucgr2 SIRSTCSCLSGSLSGIIGLTNGLGFYLASFTLVNLTILLS-QNLDNSFGF Punst1 NVKFISFCFAGAVAGTLGLENGFGLFLASTLFTSACIYTK-KYIENLFSF Rhior3 -------------------------------------------------- Rhoto1 -------------------------------------------------- Rozal11 -------------------------------------------------- Sacce1 FVQDSSALVLGLVAGFLQIESGFIWFLILYNLINVIYIVG-KFYREITGF Salro ACRTLSAILFGVTAGILALTAGFAFYLVSSAFLSVYLNVG-DWFGNAFTF Schco3 TVKFITASLAGAVAGILGLQHGFALFGASTLLTAFCLFAA-RYVDNAFTF Schpo1 FVRNLTSSFFGCAAGILGLTSGLALYVLGYFFVSFLLFAT-KYYDGAPSY Sorma NLQSLSASLFGISAGILGLESGFLFYIFFSFLTSLLMYIN-KYFNGFAGL Sphar -------------------------------------------------- Spipu1 YARSSLAFISGAAAGILGLEGGFLFYVASSLVLS-LILWK-RYFGNAFSY Sporo1 YVKSTTACIAGATAGLLGLTNGFLFFFLTALSTGTAFALS-KFF------ Stehi1 TIKFISSTLAGAVAGILGLENGFALFAFSTLLTSLCMLAS-KYLENTMSF Tapde11 -------------------------------------------------- Thetr YMRVLLAVTFGAVAGILGLTGGFALWGGSFGLASVLVVVA-GFFQSFLTY Treme1 ----LCACFSGLTAGILGLTNGFLLYLITSLLSAIFISVS-KYVESLLGF Trire2 NLHSLTASLFGVSAGILGLESGFLYYIALSITTSLLFYVG-RYYNGLPGF Umbra1 FARAGLAAISGSAAGILGLKNGFAFYAVNWVLISFLLLAH-LFFGGLLSY Ustma22 YVRSTSLSVAGGVAGVLGMTNGFGFYVISVVVTNLIVLGS-KYFENAFSF Walse1 VIRSTLSMFLGGVAGVLGLTNGLIFYLLLAPSLPLLIITQ-SYYDSLFGF Zygro1 WVQDSTALVFGIGAGILQLESGFAMFVVGYLSVALLYIIA-KYYRELTGY [Cluster2873.fasta_al_trimmed; alignment length = 193] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 LINIHNAFHQGQYLRAQLAL--GQLAAVKALAQLAESALQVQVLGGTVLQAQGEEALAVLGNLEAVALIVQIHL--QQNRVDLALKEVQAAKAQDSLLVNLAESWVYQSAFYVYEELASALSIVGQAVAEIHLGRLPEAEAALSAALEKYPEEAELIANAIVLNRYI--------LLNMI------------- Aurde31 LYHVRRLFTLGAYARAHIAL--NDVKAVRALAQSRDKALEVRVAAATAFARAGEEALETLEDLDAVALIVHLYL--SIRRPDLARREFNRASAEDDLLLQHIEASIYGNPHSYYAEQIAGHLLTARGTTHLLRGNAREAAEDFASAVKTKRGEPDAIANGVAAAIRLQQEYPTHALVDLQKKSELFDELVADY Batde5 VLALKNQFYLGSFHRAYICH--GRLRAVRILARYQQEAVAVYVLLGTVFYHEGEEALKLLKHLECIALAVQVYL--KMDRPDLAKKELDLFKADDATLAQLIESWVYQEAYYIFEEMANTRLLTSKAVAMIQARKFEEADAILLEALNKNPNDPDTLANMVIIASQLKDVAPHHPLVEQLLKESLFDRSAMRF Botbo1 LFHLKSQFYLGAYARSYIAL--SDIRAVRALATYTESVLEVKVAAATAFIQEEEEALTTLKEPECAALTVQIYL--SINRPDLAKKEYEAAKADDSLLIQLIEAAILRTAYHIYAEQAAAAINAAKGVAQLLRGNVAEAQGDFSEALRVDPRNAEALVGAGVAATTLREAHPTHPLVDLDEKVDAFDEAASKF Botci1 LLNLHNYFHQGQFLRAQIAL--GQLKAVGALAVFEDRGVQVQVLGGTVLQAAGEEALQLLGNLEAVALIVQIHL--EQNRTDLAIKEVQQARAQDSLLVNLAESWVYQQAFYVFEELAQAQSLVAQAIAEIHLGRLEGAEAALEQASSKDPENAEVLANKVVLNSSLGSTSPEHAFLDLEEKSSLFDKAATKY Caeel LFSIRNYFFLGSYYRSYIAQ--GQLAAVRRYAEFKKKILAAAVLAATILNEADQDAFRAVEGLEARASKVFILI--KMNKRKLAIGEVKKMNDEDATLSQLANALVVKDALYIYSEMSDKDLEMHQAVVSILTQDYAAAEELLESALERDNKDADVLINSIVSASQLKHEHPNHPWVDFNEKEAEFDRVASDS Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow LFPLRTAFYLGNYYRAYIAQ--KKLRAVAALATFQEAALTVAFIAAIMIFHQGDEVLKLLTHLESIALCAQAYL--RLDLVERAKKELKRMQDDDSTLTQLTNAWVYQEAYFIFQEMAEKALLNGQAVCHLHQGRLEEAESLLQEALSKDSSDPDTIANLVTVSNQLKDEAPAHPFTDLLAKERAFDRAAEQF Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin LFDVKNAFYIGLYYRAYISQ--RKLKAVRLLADYKDAVLKLPIMAASIYYHEAEAALRTLESLEASALTIQILL--TINRLDLAKKELKSMMDEDSTLTQLAQAWFLQDAYYIFQEMADKLLLNGQASCYMAQGKWDEAESVLQEAMDKDSNCPETLINMIMLSSQLKDSHRAHRFVELTIKENDFDRLALQY CocheC53 LINIHSAFHAGAYLRSQIAL--GQLVAVKLLADY--DVLSVQLCVGIILERAGEAALELLGSLDAVALIVQIHL--QQNRTDLAAKEAQRARAQDSLLVNIAESWVYQSAFYVFEELATTHSLVAQAVSELHLGRLPEAEAALQQAISIDGTSADTIANLIVLNTQLESVAPQHRAIDWASKKDEFSKAAAKY Coere1 FYSARNLLYLGAFYRAYIGQ--GNLQVIRQLAL-SQAAIIFVAIAAQILIICGEAALKILKNLECVAMTVVAYL--SINRVDLAQKLTAKLRAEDAPIAQLAEAWTYNEAFYIFEELAQARLLTALAVCKMHLAQYPEAESLLLEAFEKDSNDPDVLANLVICASQLKHLSPTHPFIDLEAKDAEFDAITARL Conco1 NYPAYNLFYLGSYYRTYLAQ--GKVEELKLIALSREELFKLQLILARLAIVEGDIALKAVRHLECVSYSVQILL--KLNRLDLAQKLFESTRSEDVPLLQLIEAWIYQEALYIFEELSQQKLLNSKANCHIHLNHYEEAEEVLVQALEKDSNDTETLINLIIVTSQLKDINPNHPYLQLNEKSDLFDSLASQY Conpu1 VYHIKQQFTLGAYARALIAL--GKLKAVSAFSQYGDESLEVRVIAATAFVRAEEEALETLSD-EAIALKILIYL--SISRPQSARKSLLTPLNPDSLPLQLSEAMLYNSSMSFYTEHLASRLLTARGLIRLARGEISAAKSDIEEALATGANDPEALAASIVALEKLVQADPEYPMVDTKEKADLFDSCAAKY Copci LYHIKQQFTLGAFARSYIAL--DNLKAVASLARYKEAALEVRVVAGTAFARAGEEALETLEDLEAVAVIVQIYL--SINRVDLARKQFERSKAEDDLLLQLIESNIFSNSQSFYTEQLANHLLTARGVTRLQRNEIQEAKSDLEEALQQQKDDAETLAAFVVAGSRLNSEHPTHPLIDVNSKAQLFDSLLEKF Croqu1 AFHAKTLFYQGSYARSLIAL--KKARAVSLLAKYRESFGELRVTIATILSLADNLAIFLLKSLESVSLLIYLYLSPKVKRPDLARMLYRAVKADDAILLQMTEAWIYQSAFYVFDEISSSTGLNGKAVTQLAMGHIEEAQANLTEALK-NPSDETTLANSIVVSEQLRSINGSHPLIDLDRQSALFDEAASKV CryneH991 LYHVKQLFYQASYARSHLAL--SSARAVDVFASIREEKVEVRAIAASVFILVGEEAVATLDDLECIAILVQLLL--SLNRRDLAQATYNSAKGSDSMLIQAMEAWILHQSYYFYEELYQLPVLASHAAAHLLLGHVDEAKADIVEASQSGQSSSDVLA---VGAEKLVTAAKQHPYADLIEKNKLFDEAAAKY Crypa2 LINIHAAFHQYQYLRARIAL--GQLVAVSALATLEEEAVGVQVLGGTVLAATGEEALTLLGNLDAVALIVQIHL--QQNRNDLAIKEVTAARAQDSILVNLAESWVYQQAFYVFEELAQAQTLVAQAVAELHLGRTEEAQSALDQALKKEPDNAEAIANSLVLQESLKKVAPQHAFLDLEEKSQLFDTAASKF Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 LYTVLQLYHCARYTRANLSL--GKLEALIKYAAFSEDIASSSLLSSCYFAKKGEAAFKRLEDLENVEFGCYLSL--LLSKTTDAQRFLDDHVASDTVGYNQTEAWILNRAYYHFDDLAGSKLLVCVLVSHLKLHHMPEAEETLSRIVSYDHRDGEALVDEIALRNKLKAEHPDSAYVDVQAKQDAFDDIVAKY Dicdi LFESKNYFYLGNYYRCYIAQ--GNIAGLQLLASYREGTLILQVIIATIYFNEQDEALQILDHIEGLSMLIQIFL--KIDRLDLAQKAYDTMKDPDATPALLSLAWILKSALSSFEEMAERLLLNGQAVCAIGMKRFEKAESLLLESIEKNPKNSDTLANLINCYNQLKTLSPKHDWTAVNEAEALFEVSKSRF Dmel LFDARNEYYIGNFYLSYLAI--DSLQALRLVHEATEELLEWHLATAIVYCHDGENALKILTNLESMALSVQCLL--RLQRVDLAKQLVAKMQSDDATLTQLAQAWVMQDAFHIYQEFCEKALLNGQAVVHLGLERYEEADSVLRESLLKKHNDYDTLINLMVHAEQLRQFYPKSDFVDLDKKSAEFDRLCLQY Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba LRLLADQFYLGDTGRAIAAS--GSLGALGNPNVVSTQPLKERLLAATLAASRQEAAWELLATAEAAALAVVLLL--RLGQVESARATLAEVKSEETIIRQLAEIWVQRSAFFTLRELTERKLLCAQATVHLVQGNLRDAEHLLLESQKLDPTNEVTLANLFVVAKTLSEVAPKNPLLQVTTFDQLFDQAAARI Fomme1 LYHVRQQFTLGAYARSLIAL--GKLKAVRALARFKDVPLEVRVLAGTAFARAGEEALETLESLEAVSLVVQIYL--SISRADLAKKEHARALAEDDLLLQSIEAAIYADSNSFYTEQLGNHLLASRGVARLLRGEVGPARSDLEEVLKGGEGEEEALCASVVAAT---------------------------- Fusgr1 LINIHNYFHQGQYLRARLAL--GQFQALGALAELTDSAVQVQVIGGTVLQAAGEEALALLGSLDAVSLIVQIHL--QQNRTDLALKEVSAARAQDSLLVNLAESWVYQQAFYVYEELAQARSLVSQAVCELHLGRTEEAQAALDQALEKDANNADAIANLLVLNQKLQSAKPDHQYLDLEEKSALFDRAATKY Galma1 LYNIKQQFTLGAYTRAYIAL--KEVKAVASLARYTESALEVKVLAGTAFVRAGEEALETLEDLEAVAIIVQIYL--SINRPDLAKKQFERSKAEDDLLLQLIESTIYANTSSFYTEQLGNHLLTARGVTRILRGEIAEAKSDLEESFAQQKGDAEAEAAYVVASLTLVSEHPSHPLVDVTQKADMFDQYAAVY Ganpr1 ------------YYRSYIAQ--NKLRSVRILASYREAALTVAVVLATLFYHEGDEALKVLKDLECAALTIQTLL--KINRIDLARSTIANVKAEDASLAQLAEAWVAQESYYIFEELASPKLLSGQAACRIVQGKLPEAEQLLMESLNRDSTNPETLVNLIVAANALRDAAPAHPYLELALKESLFDRSASRF Gloin1 LFALKNLFYTGSFYRAYIAQ--GKLQVIKILAIYSNGSVGVQIITGTIFYHEGEEALKILKNLECVALIIQIYL--KLDRLDLAKRELASTKSEDAMLAQLIEGWVYQEAYYICEEIAQSKILNGQAVCNIHLGKHAEAETLLLEALNKSNDDPDTLVNLIVVSNQLKEASPNHAFLDLDLKSSLFDRAAQRF Hisca1 LLNIHNAFHQGQYLRARIAL--GQLAAVKVLAQHEAEALKTQVLVGTVLQAQGEDALSLLGSLEAVALIVQIHL--QQNRTDLALKEVQAARAQDSLLVNLAESWVYQSAFYVYEELASVLSIVGQAVSELHLGRLPEAEVALRSALEKYPNDVQLIANSIVLKSSLEKAQPDHPFLDLAEKSAFFDAAASKY Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LYHVKQQFVLGAYARAYIAL--HDLKSAASLARYKEAALEVRVLAGTAFAQAGEEALETLEDLEAVALIVQIYL--SINRPDLAKKQFDRSKAEDDLLLQLIESTIYSNTSSFYTEQLGNHLLTARGVTRIFRNEIPEARSDLEESLQQQKGNPEAEAAYVVAATRFAAEHPTHPLVNVNKKAAAFDEFAAKF Lenti61 LYHIKQQFTLGAYARAHIAL--GALKSVAALARFRDAALEVRVLAGTAFARAGEEALETLQNLEAVAYTVQVYL--SINRPDLARKEFERAKAEDDLLLELIEASIYSDAHAFYTEQLANHLLTARGVARLLRGEVSAAQSDLEEAQSQGKPDAETLAAQTVAASQLSSEYPNHPLVDYQQKADLFDELAAKF Malgl1 VFEAQSLFYQSAYARAALAM--GDAMSVLLLADFSEDVIQVRYQVGLALHENGKNALETLTELECIALGVHILL--EIQRVDLAEKEYLAARNDDSILVQYMEAWITQQAYYVYDEMSQNPSLVGKAVAQAAQNDVPGATNTLNEALALDPQHTLALANQGVVQPEAESTTNMYAKTPASALVSFWD--TKRY Mellp23 TFHAKTLFYQGSYARSLIAL--KKAKAVTLLAKYKESIGELRVTIATVLHLIDNLAIFLLKSLESVSLLIYLYLTSKVKRPDLARMLYKSVKADDAILLQMTEAWIYQSAFYVFDEISSSAGLNGKAVTQLAMGHVEEAQANLSEALKANPKDETTLANSIVASEQLRSINPSHPLVDLDRQLALFDEAASKF Mnele LFMVKTAFYIGNYYRAYLAE--GKFLALVLLAKIKDAIVSVALLCANVYLQAGESTLRVTSSLECHALAVQTLI--QMNRVDIATKEMKKMQDEDATVSQLSLAALVQTAYYVYQELADKILLNGQAVCFLLQGKPEQAEDVLQKALDKDSGHPETLINLSIVSSQVKDSHPNHPYIRLEEKEKLFDELSSAL Monbr LFDVRNALYIGNYYRAMVAQ--GKLQAVKLLARYRASVVEVALVLGTIFSQDGEQALKCLEAVEAMALYIQILL--QMNRLDLAKKKLSELQDEDSTMTQLATAWVIQEAFYIFQELSDKLLLNGQAATHVQQGQYDEAEEALLAALEKDSNNAETLINLVAVSNQLRDSAPEHPYVDLAEKEGLFQTFCQQY Morel2 LFAIRNLFYSGNYFRSLIAT--KNLQALKAQAVYRDAALAVKVVVGQVLATEGEEALTVLNHLESVAVVVQIYL--QMNRLDLARKEVEACKAEDAMLAQLMEAWVYQNAYYIYEEIATSKSLIGEAVCNIQMGHYPEAEGILQEALSRDPSNTDAIVNQIVLSQQLQSVAPNHSYLDLDLKSSLFDRAAQRF Mucci2 LFGLRNLFTVGNYYRSYVAQ--GKLKAIKLLAEYAEDYVVVQVTLATILVQAGEDALRTLKKLECSALAVQIYL--QLDRLDLARNEVASVKAEDALLLQMMEAWVYQEAFYIYEEFAQSKVLNGQAAANLALGRYPEAESLLLEAQNKDSDNPDTLINMIACASQLREVAPQHPYLDLDLKSSLFDRSASRY Mydma LFEVKNSFYIGNFYRAYIAQ--NKLQAVRILADYRKQILKL--IAAIIYFHEQDSALRCLTALECAALSVQIYI--SMDRLDLAKKELTRMQDEDATLSQLATAWFAQDAYYIFQELCDKALLNARASCYIRMGKFEDAESSLQESQERDSNNPETLINMAVLAAQLKSGHEANRFTDYIAKEEDFNRIVSSY Neucr2 LINIESHFYQGQYLRARIAL--GQLEAVGALAQLAESAVEVQVVGGTVLAAAGDEALALLGNLEAVALIVHIYL--AQNRTELAVKEVASARAQDSLLFNLAESWVYQQAFYVFEELAQARSLVSQAVAEIHLGRTEEAQAALDQALKKEPGFADAIANQLVWSAALEQADPNHPFLDLAEKSDLFDKAATKY Orpsp11 LHIIKNNFYAGNYFRSLISL--KQFCAIKLLAQYIENVLNVILMFAIIYNYEENEALQILKNLECTAFYIQLLI--KINRTDLAQKEVSQMKADDAALAQLAETWLYQESFYIFEELSQSKLLTGKAICKMHASNFAEAEKLLLESLNKNSNDPDTLVNLIICSMHLNEVYPNHPYIDYEEKLTLFDNAAKRY Pench1 LLNIHSAFQSGQYLRSQIAL--GQLSAVRALALQTDAALQVQVLAATVLQAQDEEALALLGNLEAVSLIVQIHL--QQNRTDLALKEVQAAKGQDSLLVNVAESWVYQSAFYVYEELASALAIVGQAIAEIHLGRLPEAEAALTAALEKYPTDVELIANTIVLNSRLQQVQPSHSLLDIQEKSEFFDTAAAKF Phybl2 LFGIRNLFTLGNYYRSYVAQ--TKLRAIRLLAIYPTDAVKVQVAVATLYVNDGEEALKVLKKLECAQLAVQIYL--QMDRVDLARNEVNQCKAEDALQLQMMEAWVYQEGFYIFEEFGQSKVLNGQAATNLALGRYPEAESVLLEAIDKNNDDADTLVNMIVCASQLREVAPLHPFLDLDLKSSLFDRSAARF Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 LYHVKQQFTLSAYARAHIAL--NNLKAVAALARYKEAALEVRVLAGTAFARAGEEALETLENLEAVAIIVQIFL--SINRPDLAKKQFERAKAEDDLLLQLIESSIYSNASSFYTEQLGNHLLTARGVTRLLRNEIPEAKSDLEESLSLQKDDAETLAAFVVAASRLTSTHPTHPFVDVAQKEASFDELAAKY Polpo LFEIKNYYYLGNYYRAMIAL--GDLQAVRLLASYAETAVAVQLVASTIFYNESEDTLRILDNLECMSLLVQTYL--KIDRLDLAEKQYAQMKDVDATPSLIASTWIVKVALSVFEELSEKLLLNGRATCEILLRRFEKAENLLLLSLEKNSKDPDTIANLIACYSQLKSTSPKHHWLSQLHAEQSFDRSKTRF Pucgr2 DFHVKTLFYQGSYARCLICL--KKARALTLLAKFIDKFGELRVTLATILTLAESLAIFILKSLEAVAALISLYLSPRLRRPDLARSLYTSAKADDAILLQMAEAWIYQSAFYVFDEVTNTVGLNGKAITQLAMGHVEEAQANLTEALKADPENENTLANSIVISQKLKTLNPKHPLIDLDRQSALFDEAASQF Punst1 LYLVKQQFTLGAYARAHIAL--SNLKAVSALARYKEEVLEVRVLAGTAFIRAGEEALETLHNLEATSLIVYVYL--SINRPDLARKEFDRAKAEDDLLLQSIESSIYSDPHSFFTEQIANHLLTARGITRLLRGEIAEARSDLEESLSH-GSNAETLAASVVAASRLTSEYPSHPLIDLEKKAEEFDQFSTQF Rhior3 LFGIRNLFALGNYYRSYIAQ--GKLKAIKLLASYSDQHVQVQVITATILVQACEDALRILRKLECSALAVQIYL--QLDRLDLARNEIASVKAEDALLLQMMEAWVYQEAYYIYEEFAQSKVLNGQAVANIALGRYPEAESLLLEAQNKDNDNPETLINLITCASHLREVAPKHPYVELDLKSSLFDRCASHY Rhoto1 SYYIVQLFQQGSYARAHLALTPPAIRAITSLAHYTESAVGVRGVIGTVWVLEGEEGIEILKDQECLGILSHLYI--SLNLPHLSSALLSSPSTSDSLLSQLLVARSYQDAYYVFEEIKGMGVLAGVAVAQAALGRWEEARDATNEALEMNPTHPTSLANSAALAAQLRAADASHPLVDLEAKSSLFDDAASRF Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LYHVKQQFFLGAYARAHIAS--DDVKAVGALAKYKDAALEVRVLAGTAFARAGEEALDALEDLEAVAVLVHIYL--SINRPDLAKREFERAKAEDDLLLQLIECNIYANPQSFYTEQLGNHILTARGVARILRNEFQAARSDIEEAMQQNAGDAEALAAYTVAAARLQAEHPNHPLVDLAAKSSIFDEFAAKF Schpo1 LYFVRQYFYSGNYARAKLAL--GESAAILALAG-MELIIDVQTLGAIFQIKNGDDAMDLLENLEAVALQVYIHL--REHKIEAAEQTLKQALADEEIVLQLAQSWIYNDAFYVFEELNG-MTLTGMACADICLLRPEEALSSLKTALDSQPNYEEALSNMTTAISSFTNSS-TLKLNHLNEKAQEFDTFSTQF Sorma LINIESHFHQGQYLRARIAL--GQLEAVGALAQLVESAVEVQVVGGTVLAAAGDEALALLGNLEAVALIVQIYL--AQNRTDLAVKEVASARAQDSLLFNLAESWVYQQAFYVFEELAQARSLVSQAVAELHLGRTEEAQAALDQALKKEPGFADAIANQLVWSAALEQANPSHPFLDLAEKNDLFDKAATKY Sphar ---------MGN--------------------------------------------------LECTALLVQLLL--QYDRVDLANKYLQQMSDDDSSLTQVATAWVYQDAFYIYNELAAKMLLTGQAACLIHQHKYGEAEDLLQDALNKDSNNAEVLVCMITVASQLQDSAPSHPFVYHAAKGEQFDRVSAQY Spipu1 LLVLRNSFYLGSWYRACVAQ--GKLRGVKCLARYKSKAVQVQVLVGSVLYAEEPEALKAARNLECVALAIQTYL--KMDRPELARKEVEKLKADDATLAQLAEAWVIQESQYIFEELASSRLVAGHAICKMQAGNFAEAERLLLEALSRYASDPDVIANLIVCASQLRQVAPQHPLLDLVLKESLFDRAVQRY Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 LYNVKQQFFLGAFARALIAL--GDLKSVAALAKY-DAALEVRVVAGTAFARASEEALETLENLEAVAVIVQIYL--SIHRPDLARKEFERAKAEDDLLLQLIEASIYSDCNSFYTEQLANHLLTARGVTRLLRGEIPEAKSDFEEAVSQGHEDAETLAASVVAASRLATTFPTHPLVDVNSKADLFDELAAKF Tapde11 LYNEKNAFYKGQFLRAKVEL---NSQAAYALALHTTEALKVQIIIATVFARDSEDAIDVLDSLEAVALLIQVYL--STNQLSSAQSTLQSAKAQDAELIQLAEMWVYQNAFYTAQEFADTRMLLAQSVIEIQLGRYDEAEGTLLQVLNKDPSSPDALANQVVLWEKLKSVDASHPLVQIEEKASEFDSCAANY Thetr LFEVKNFFHLGCYFRAYAAL----TDATALLAVRRATALEVVLGAAQLMVADGDEALTLLTELEPMAYMVYVYL--QMNQVRYAEEKVKAMVEEDNTLTQLAGAWVLQEAYHVFQDFVDKKLLNGVAACCMHQGNFEEAEAVLVSALELNANDADTLANLIALAAQLAARDAAHPLLSKADLETRFAAAAAAL Treme1 LFLVKQLFYQGTFARAHLAL--HPARAVTALAKY--SKVEVRVIAATVFILENEEAVATLEDLECIALLVQLLL--SMDRRDLAQSAYASAKGNDSALVQAIEAWILHQSYYYYEELYQLPVLASHAAAHLLLGHVEEAKADVVEASQRGDTHPDILA---IGTEKLASLAVQHPFADLKNKNLEFDEAAAKF Trire2 LINIHTHFYQSQYLRARLAL--GQLEAIGALAEFTDSALKVQVVGGTVLQAAGEEALALLGSLDAVALIVQIHL--QQNRTDLALKEVTAARAQDSLLVNLAEAWVYQQAFYVYEELAQGQSLIAQAVCEIHLGRLEEAQSALEQALQKDPTNAEGIANLVVLNESLKKANPHHQLVDLEEKSSLFDKAAAKY Umbra1 LFAVRNLFALGNYYRSYVGQ--GKVQAIKLLAIYAEQAISIQLATATIQVNEGEEALRILKNLECAALVIQIYV--QMDRIDLARKEVASVKAEDALLAQLIEAWVYQDAFYIFEEFAQSKLLNNLAVSNLALGRYPEAESQLLEALNKDNNDADTLVNLIVCSNQLRDVAPQHAFLDLDLKNSLFDRAAARY Ustma22 LYQVQSLFYQGAYARSHLARSPSDVQAIQSLARFSRETV-IRCAAATALFLDGEEALNTLKEIECVALGVHILL--SIHRLDLAEKEYLAARADDSLLIQLIEAWITQQAFYVYDELAQNPSLIGKATALAANGDWSGAKKQLDQAASLDPTNANILANQAVVQQQLKQVSAFHPLLEYQALEKAFDQHAAKF Walse1 LEDIKQFYYQGSYILSHLALK-KDLAVIQSYIDYKVESLDFNVLAATIFWKSGEEALSTLKDVESVALLIQIYI--SISRLDLAKNEYQHARADDHYLIQLSEAWLYEQAYYVLEELPDRLL---RAIAHGALQHFEEAQVELDS----NSEDEYSIMNEIVISSRLSSINPDNILVDLKRKSAEFDQLSKQF Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2875.fasta_al_trimmed; alignment length = 308] Allma1 KPDQDKHNALIKDLNRQKMTEIRNQTKRQDLRSKLETVKKQQDELVRTKEDLLKRLLVLNTSVKAEELNAISQRYSSLDAVQARI-QTLEAKIASGTLKLIDERKAANELAQLQRCEPLFATRAAKEKEIEQDRAEIAAVEA-KLATLQPSAGGLAQSFEDVKKELDSLALAKKKAQDLYKQRNALQDQLAKLTDERNRATEEHYKTLREERERKAKRLADQRERERVAQEELERAAVPADEMAICRNLIAYLFKFPLTVMENFWKVKVDVPVTAADAPVAIAALNQKFQTHQ-KLATLRNQALAKAR Ashgo11 RPDSSVRDRKLEPLYDQEVTAVRKQISKQKLHEQLKEIIRAQSDLKGKRQQIHDRIKQLDAQIKRGEVAERVGRYSSGEEIRERL-AQIDEEISSGGLSLVEEKLRVKEMQALNKLAKDLQQVEPVKRSIEEDRAAIAELKA-KLN--SLNPKEVSAQFESTQAKLNQLQSKNQQRSRLFTKRSALYSKRDEIFAQIKKEFKAYKKKLDDDRIKREEEERISRDKEEKLQEKLIHAHKPAYEISAIETALFSLFSLEPTLIVVLADLDVSVPMTKDDVPATVDQLKAKFLARQ-DEQTSKNVAEAEAA Aspfu1 KPNEEAFKADLAQAEQEKLNQIKAKIRQQELRAELSSIRQKQQGFKASRTSTQEKINALELTLKATEQNNSRTRFKNVEDIDREI-ARLEKQVDSGTLRLVDERKALSDISTLRKQRKNFAGLDEQQKVINDLKAQIATLKK-TLD--NPEAKALSDKYTEIQKELDAIKAEHDNLNALRDERTKLHAEQQKKWNAIREARKAYKEYEDEAWRIRREKQKAQREREKKADKKLEEASRPADEILIAQGLIRHFFNLNVGVIEDFAKVKIDPPMNQSDVPAVIEKLAAKWKANQ-AAKTQENIKKAQEE Aurde31 KPDADAYKAEQEKIRQTKLNAVKDKIRRAALRAEQDSLRAAQGNNKVSSERLREQIKAIQDNVQKQDIQAAKKKFKTVAEVDAAI-KNLDRQVESGSMAIAQEKRALAEISTYKRARKTIEGFQAEEDAIQAERAKADALRN-ELN--DPEAQALSARYTAIRKELDEIKEQSDDRNKLFDERNALQKEINALHERRREAHDRYWQKVNEDRARRAEKYRAQREEEKRIEQIREEARIPASQIEDCQTLIDFFLNIPLPTLTALLSLSIPPPASHGEIERTVDDLKTKFEANQ-RRQTEENVKKGEEK Batde5 KPNQDRHNAEIQEIRQQKMKEIQDKIRKNELREKLSVHLQEIKELAGKRTKLVDQLTALQSALKKESERTEKAKHRTVESVDSRI-DEIEKQIQFGQVKLIDEKRMVSEISNLKKVRKVLEGYSQQQTTNDNDKAAIETLRA-ELKTLDGQRASLRELADTTRAELNKVAESLSSLSGLLEQKRAIKSQVDAAFEKMRTARDEFYNWEQEERQKRQEQFKQKQREARIAERELEDADIPAEEINLCSALIHFLVRLDILTVNQLIALKIDIPVSSDNVPATLASLNEKFLSEQ-AAQTAANKQAAQAR Botbo1 RPDQAAYNAEQEKIKQAKLNAVKDKIRRAALHAELDGIRGQQAEHKAKRTKILDEVKAIQATVQKQELQTAKQKFKTVADLDARI-KQLEGQVESGSLKLVDEKRALTDISTYKRFRRSVETFQADQEAIDADRARADELRK-ELD--DPESKAISERFDAIRAELDEIKKAGDNRNKLFDERTELQGQLDTLYGQKREANDRYWQKVNEDRARKAERYRAQREQEKRADRLLEEAQIPATQIEDCQTLIDYFLNIPLPTLSALMQHAIPPPTSSADVPRTIENLKTKYEANQ-AHVTAENIAKAEAE Botci1 KPDEAAFKAKLAQAEQEKAAAAKAKLRRNELISQLKEIKEQQGAGKAGRLQVFDQIKKIDEQVKANEQKVAKGKFKNVDELDREI-DRLQKQVDAATMKIVDERKTLTEISNLRKQRKGFAGFDDTEKSIEALKAKRKNLQD-SLD--DPESKALSEKYSKLQGELDILKAEQDNFGTLKAEKDKLQAEQQEKWLALRQAVREASKCDYYPRQKARDRSKLEWQPVAKAQMMLAECQ----------------------------------------------------------------------- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 RPDDKAIKEEIEKLKDLTNNEINAQIKRNKLQTELKSLIAKQSQGKNERQLINDQIKAIDASMKKAEIQQQTSKFKNVAEIDSRI-NYLDGLIDAGNLKLADERRFVKEMSSLRKLRKDFGSIEKTQELIDQDKAKIAELKK-KLS--ATHNKEVQAQFETIQKELDAINESNKKRDELRDKRTEIKKQKDAKYEQIRKKFASFKKQLAEEKKRRDEEYKQRLKQQKKAEKELAEASIPAEEINSIHTLLSYFFTVAPEVVVALSDLTIAFPTKEEEVPETIKTLKETLEEKQ-EEQTKINIERAKAR Cangl RPDVSVRDKKLETLNDEELNQLRKQIERKKLQEKTKEIIKTQADLKARRNAIHDSIKQLDSQIKRGEIQDRIGKYTTTAEAKQRI-NQIEDQISTGDMSLVEEKMLVKELNSLNKLIKDLVAIDPIKKAIDTDKDKIVKLKE-ELS--GMNSRELSAQFDENQKRLNELQSSTQKRQTLYNKRTALYKKRDEVYSQIRKEFKAFKNKLEKQRLKREEEEKLSKEKDAKLQEKLTHARIPAYEIEAIENTLVILITLEPTLIATLAELDVTVPITQDDVATSVEQLKKKFKSNQ-DEQTEKNIKAVEEQ Capow PPNEDAHRQAMDKYTEKQLNELAQVIEMSRKRDTLKEVRDAKQALYERKTALDDRLKAIFEYIRQGELLLLRKDIRDANEIDTAV-RNLEYQLSHGSFNMTEERRLFAEIAKLKQSKNRLAEYEQVRAGIDVERQAQAKARQ-ELDEVMAQLKPLFAKENAIREELDALRLVQDTDG--FAQRHNLTKELNNLYLARRERRQDWFEATKEDRERQRIEREEERHLEISEARRKDFAEAEAAEKQIAHRLIGYLLTHALAIHNDFVRIRLSAPATAGDVETSIQEIRAR-LVDL-DRGTAAHREKHAKE Catan2 KPDFDKHTASVKAINKAQLTKLRDRIQRDALRSKLTQVKKQKADVQRDRDDTIRRIAQLQDQIKAEEYKHLKDRVTSAEEAEERI-RQLESRIASGSLKLLEEKKAINQISQLKRSKPLFDTLRTKAADIANDESELSDLQV-KLATLSPSAGDLTSAYDDVKRELDRLADPKTKLGVLYKERDDLSAKLNELYAQRTRAKEEHYRTMRDERVRKQKVYAEEKELEKLAQEERERAEVPAEEIQICTNLIAFVFKFPLTVMEHFWHVKVEVPVSTAEAEAAIKALIDRYQKNS-AAVTARNKAAAEAK Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 KPDEEKYKEELAKLEQEKLNACKAKLRQQELKTELNAIRQTQQGNKSGRNAIFEKIKKLDDQLKQAELKTAKGKYKSVEEVDQEI-ARLQKQVDGGMMKLVDEKKALAEISALNKARKNFSGFDAQQKKIDDIKAQIAEQKK-LLD--DPENKALSDKYTKLQTELDALKAEQDNLRTLREQTDKARAEQQEKYQARKDQLRAYKTYESEARKIRFEKRRQEQVASKRASKRLEEASTPADEIIAAEGLIRHFFNLNIGIIEELAKVGVEAPSSQEDVPATVEKLKAKWKEDQ-DRKTKENIAKAQKE Coere1 RPNIEQHKKQLAEFDRKEQDEVRRGLERNKLVASLQEIRTEQNNLRKSRGKVFDRQASLTASIRKAELKAQQSKYKSIEEIDREI-TKKEKQIESGQLKIVEERRLASEIPSLRRAKKLVEQVATAQKAIDQE---VAELAKIDAELGDTNAQALGDEHERLQNELDGLRASQDQRDSLLSKRARIMKELDSAWDEKRANNNAFYHWQQEERKLRALKEKGERQREERAQARREEAEVPADEINTCNTLIAYLLKLPLVVAEQFLELRVDIPTNTIGIAAALKSLAVRFIDQQ-PKATEEKKRKVEEE Conco1 RPSRDVMLEKVKAVEQAKLFVVKDQIKMTNLKQKLNVLREEQSEIKKSRTNVFTQISQLQASIKKSELDAIFSKFKSLDALEDHI-DKLESKVESGTLKIIEEKKALQELSQLKKFKKNFSNVSTLQESIDADNQNLDQLRT-LLN--DSKSEIINSSYDSIKGELDDLYKDDQDKTKLYAKRDELQKEINALYDEKRAANENYATWKRENEARKKEEEEKNKEQDRLIAEEREAAEAPASELNLCNGLLAYFLKIPIGVMESLFSLKIQAPLSVSEVQSTVEKVQEKYLDNQ-DRVTEEKKAKLESK Conpu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci KPDKKAFEAEQDAIKQTKLNAVRDKIRRNELLNQLNEIKGHQSLNKSSRLKLREQIDAKQEALQQKALQNAKAKFKTVAEIDAHI-KNLERQVESGNMKLADEKRALAEISTTKRSRRIVEGFQADQEAIDTDKREIEELKK-QRD--DPELKAINDKYDAIKAELDELRKQGDQRNKLYQERDALQAELKELYNRKREHNDRYWAKVNEDRARRAERARAQKELQKKAERLLEEAQVPAAHIDDCQTLIDFFLNVPLPTLSALLSMSIPPPTSTADVPRVIEDLKTKYEANQ-DRVTAENVAKAEKE Croqu1 RPDKLAYEREQVALKQARLAIVREQIRRQKLRSELDGLREEQSKGKSSRGKILDQIKAGNEVVQRKELNNGRSKYKSSAEVDAKI-RQLDAQIESGTMKIVDEKKALAEIQNLRKQRKLVEAFGPQQEVIEAEKAKVESLRK-LLD--DPDNKTVNDRWGAIKAELDKINNEMNGRDKLFEERNQLQDSLREALNKRREANDKHYAKIQEERQRRIDRQKAEREATELHTQMRDEASAPAREIEDCRTLILYFLQLPLSTLNALHALAVPPPMTRDDILSTVTALSEKFTENQ-ERVTKERVKEVEAK CryneH991 KPDQSKYNAEQDEINKEKIEAVRSRIRRSAIKAELDSLRSEQAKFKGDRNKLFEEMKRLQEGVQKKDVQGQRNKFKSVADIDARI-ESLDKQVESGSMKLVDEKKALQEITTLRRSRKTLEASGSIDESIAADKAKIDELKK-QLD--DPEAKKVSDRFDELKKEMDGLREEGNERGKLFDERNKLSAEMDELYDRKRKDNDKYYAKVQADRQARQERFKAEKDAERRIARLREEARAPASETDDCGVLINWFVNLPMSLLSTLLSLGISPPSGKDDVQRTVDDLETKFEANS-AAKTKAEIERVEKL Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 RPDDKALKQEIDGLKDLTNNEINAQIRRKELQGQLKELVGKQSTIKNERGAILDQIKGVEAQLKRSEIQTKTSKFKNVQEIDSRV-NYLDKLVDAGDLKLADERRYVKEMSSLRKLRKDFGSIEKQQELIDQDKAKIAELKK-KLN--AVQNKEVQQQFEKIQKELDQINDDNKKRNDLFGKRNEIKKTKDGKYDQIRKEFEKFKTLMTEERKKRDEESKQQQKKQKRAEKQLAEASIPADEINSIHTLLAYFFTVEPDVIVALGDLSIPLPTQADDVSSTIDTLKETLEDKQ-EEQTKVNVEKAKAK Dekbr2 SPNFKERDQKVNDIRDAELSKINEEIKRKELSSGLEEVIKKQGELKRKRGDISSQIKAIEMSMKQNKIQGKTSKFKSVGELDKRI-KHLEELIDTGTLKIVEERRFVKEISSLRRMRKDYASIDAEQKSIDEDKAKIKELRK-SFG--EANAREEETKFEDLMKKMDE-----S-------------KTKDIK-----------------------EEEKEGKEKADK-------------------------------------------------------------EKKD-EEN----------- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 RPDKKEYDAEQESIKQEKMNAIRSKIRRTELRAEMDKIRQEQGKFKNSRGQLIAQLQSLNEGISKKDLQAAKSKFKSVADVDAHI-KQLERQVESGTMKLVDEKRALAEISTCKRLRKTVESFQADQEAIERDRAAVDEIRK-QLD--DPEAKAISERGDAIRAELDEIRKEGDNRNKLFEERSELKAQLDELHGKKREENDRYWAKVNEDRARRAERARAQREEEKRATRIREEAAVPAAQIEDCQTLIDYFLNIPLSTLSALLSLSIPPPASASDLPRTISDLQTKFEANQ-TRVTKENVAKAEEQ Fusgr1 KPDEEVFKKELAKAEMDRLAAVKAKIRRQELIAQANEIRQKQAGGKNARTGKLDQIKRLDEQVRSAEQKTAKAKYKSLEDVDRQI-ATLDKQVNSGTMKLVDEKKALSDISSLRKMRKNFGQFDDSQKQIDDLRAKIKEIKD-SMD--DPEQRALSDQYNKIQAEIDTIKAEQDGISSLRDERTKLQAEQQEKYTAIRKQKKAFQAYDREAREARREKQRAEQHQERKAERRLGDASDPADEIRRANSLLQFLFSVPPAVVEDCAAMGIDPPMSAADIPTVAEKVRAKWKNDQ-EAQTQRNIEKAKKE Galma1 KPDKKTYDTEQARIKQVKLSAVRDKIRRTTLRAELDGLRDKQSSNKNSRGKSMDQIKAIQDGIQKKDLQAAKSKFKNVAEVDAHI-KNLEKQVESGNMKLADEKRALQEISSTKRNRKLVEGFQAEQESIEADRQKIEELRK-ELD--DPASKAISERYDAIKAELDELKKESDGRSKLFEERDNIQSQLKTLFEEKREANDRYWNKMNEDRARRAEKARAQREAQKKAERLLEEAQAPAAQIEDCQTLIDYFLNVPLPTLSALLSLSIPPPVSSTDVPRIIEDLNTKFEANQ-ARVTAENITKATAE Ganpr1 RPDQDAYNTHMAGIN---QNNIRESLRRQELRNQLTEIRKQQQEIRTSRGKILDKLKDVRNNIKR---------------------------LESQSHKLIEEKRIVQEISSLKKARKVVETFSGQQEGLDEDKRTAEELSK-QLEAFDPQRAAFEEQYTALSAQIATLDKEKDRLNEIYNERNGIQKELETEFNRRREQKEEFYNYLQEERKRKAEDAKRRQKRERLAEKEKELAEIPADEINTISNLITFFLKLDMSVLESLFKEGVEPPAGYDQVEDTLKKLVEKYLENQ-AKQTEENKRKAEEK Gloin1 KPDDEGYKAALEDI-QNKLNAITDKIKREELFARLDKLRGKQAETKRNRSNIFEQLKSMNESLQKRDLQQSKNSYRSIKEIDNAI-ENYERQIESGTLKIIDEKKIIANISNLKKSKKSVKLFETQKNAIEEEQKKIDELKK-TLD--DSDFKKNNEEYDDVKAQLETVSKDCDKRNELFDEKKRLTAQ-------KRESKQEYRKYQEEENKRRQELKRKQAENQYKMARKREEAAVPALDILNCENLINYFFPLSFSIMEQLTSLDVAVPLNSSEIEQTIESLFQKFIENQ-DRVTKENMEKVEAE Hisca1 NPSEEVYKADLARAEQKRMEEVKAKIRAQELRAELSSIRQQQQGFKASRNSLQEKINALEASIKSAEQKASRSRFKNVDEIDKEI-QRLEKQVDSGVMKLVDEKKNLAEISNLRKQRKGFSGFEESQKFIDNLKSQLHELKK-SLD--NPEAKALSDRYSAIQQELDAMKAEQDNLNALRDERTKIYGEQQKAYSAVREARRAYKEYEDELYRIRRERQKAEREREKRADKKLEEASRPADEILIAQGLIRHFFNLSFGVIEDLASVKADPPMSQADVPALITKLAEKWKAQQ-ASKTAENIKKAQEE Klula1 KPDVTVRDKKLEPLNDQELSLIKQQISKEKLQGELKEVIKTQSDLKAKRQQIHDQIKFLDAQIKRGEINDLVGKFQNVGQIKQRL-AEIDDEIASGDLSLVEERLRVKEMQSLHKLSKDFQVVEPIRKSIEEEKEQIDALKK-ELN--ASNPKEVAAKFETIQGQINNLNSKNQKRKTLITKRSALYNKRDEIYTQIRKEFKSFKKKLDEQRLKREEDEKLSKDKEEKLQERLNHAKQPAFELESIENMLTVLFSLEPSMIALLAELDIRVPLSKGDVPATVEQLKAKLTAKQ-PEATEKNIAEAEEQ Lacbi2 KPDKKAYDAEQDKIKQIKLTSVRDKIHRNALRAELDSIRDKQSANKTSRGKVLDQLKSLQDGAQKKDLQAAKTKFKTVAEVDAHI-KQVPNIVESGNMKLAEEKRALQDISSSKRNRRAVEGFQAEQESIDALRHSIDELKK-QLD--DPESKAVSERYDAIKAELDELKREGDDRSKLFEERDNLQSQIKNLFNEKRDANDRYWNKVNEDRARRAERARLQREAQKKAERIREEAQVPAAQIEDCQTLIDYFLNVPLPTLSALLSLSIPPPSASVDVPRVIEDLKTKFEANQ-ARVTAENISKAEAD Lenti61 KPDKALYEAEQNKIKQVKLNAVREKIRRNALRAELDGIRGQQSTSKLARGKVIEQLKSIQDGIQKKDLNAAKAKYKTVAEVDERI-RHLDKQVESGSLKLVDEKRALQEISQCKRSRRIVEGFQTEQEAIEAERAKADELRK-ELD--DPEAKAASERYEAIKAELDELKKEGDSRSKLMDERAAIQAQLDELYNRKREANDKFYTKLNEDRARRVERQRAEREEAKKADRLREEAEVPAAQIEDCQTLIDHFLHVPLPTLTALLSLSIPPPTSTADVPRVIEDLKTKFEANQ-ARVTAENKAKAEAE Malgl1 RPDQKHHNGEIERLKHAKIAQIRAALRRAALKEELNSLRSEQAGRKGTRGKVFDELKQVQDDISNKALQQAKSKFKSTAELDAQI-SQIEAQIESGSMKIVEERKALNEVSTLKKSRKSVEQFGAQQKEIDTLRAKIDELRS-LLD--DPDMAAANKRYEAIKQELDDITKEQESRSKLMSQRTALSKRLDELYQARRDENDKYFARVQAERERRQEAIRKEREHARQVQQLRDDAAIPAKEIEDCDVLIRFFLNVPFGMLSALLNLSIPPPTSHADLGRVVDNIKLKFVSNQ-PHQTQENIRKAEEK Mellp23 RPDKAAYEREQTSLKQAKVTAIRAQIRRKKLRNEMDSLREEQSKGKSSRGKLLDQIKAGNESVQRKELNTSRGKYKSSAEVEAKI-RQLDSQIESGTMRIVDEKKALAEIQNLKKQRKLVDAFGPQQEAIEAEKAKVENLRK-LLD--DPENKNVNDRWAAIKEELDQINAKLNGRDKLFEERNQLQDTLTELFTKKREANDKYYAKMQEDRQRRIERQKTEREASELHNEMREEASAPAREIEDCRTLILYFLQLPLSTLNALHALAISVPMTRDDVAATITSLSEKFTDNQ-ERVTKERIADVEAK Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KPSQEEKDQTLKEIERPRLNAVREAIPRTSLRKRLGELRDKQAENKKGKQVKIDQLTALNNSLKKADLKAIQDKFKTQDAVEAQI-NKLEKQLESGSLKLVEEKRILAEISSLKKAKKSVDAAQAQQIAIDADKAAIAALKE-TID--DQTAKALSAEYNQIQAQLDEITKSKDKRNDLFDERTRLQKELDTEYQRKKTALREYNKHQQEMQVRKREEYQAKKLEEKRAKEERELAEIPANEIITCDSVYKYLFKLPLAVLEQLLELKVVVPTSPADLEKTLDALIEKFKANQ-EKATAENKRKAEER Mucci2 --------------------AVREKIRREEIKAELNEIRDKQAALKKTRKAVYEQLDAINDSIRNGSIKGFQTKFKTTEEVDARI-AELESKIEAGV-RIVEEKKMLQEISMLKRNRLSVEDVDGQQAAINKEREIYGELKK-NID--DSEAKKLSDRYEELDAEFKLLHADQSARNQLYDERNRLKALLDEQYQKMRTNNDEYYTFVRQLREYKREQEQLRKENEKRAKQELELAALPASEIALCDNLAIFLLKLPLATMEAFFDIKVTVPTKISEIPATLTKLKERYIAEQ-PKATELNKKKAEEK Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 KPDQDAFNENLAKAELKKYNEIKAKVKRQELISQLNEIRQQQAGGKNARTSKLDQIKRLDEQLRSAEQKTARSKFKSTEELDREI-ERLEKEVNGGMMKLVDEKKALAEISNLRKQRKSFAGFDDAQKQIDDLKAKIKEIKD-SLE--DPEAKALSEKYNKLQAELDAIKAEQDNLSSLRDERTKLQQLQSEKYQAIKKAKKEFAKWEREQREKARERQQAERAKERRAQKMLAEASDPAEEIRRANSLLKYFFSLPPSVIEDCSFVGVEPPMAATDIPAAVEKIKAKWKADQ-PEQTRKNIEKAKKE Orpsp11 KPDQEKHNAELETIKIEKRNKISGKFERNELRQTLEKIRIDQGKIKKQRQEAIAKVKELQALRRKDELRSAKQKVSNVKDIDAQV-KQLEKQIEAG-VSVNEEKQLLKEISKLKQAKNTLDKVEKSVAEFNVED-KIKALDA-KIKKFDEERKPLEKQYTEVKAKLDALEDKRRDFKSNKEERDKIQKEIDANIQKRRDQREEYRAFVKADRERKEEERKKKIRDERLFEAELELAEIPAEEINSCNTLIGILIKFDLGVMEAFWKLKVDVPSSTEEIKDAIKTLEEKYQKNS-AEQTKKNKEEAQRK Pench1 KPDEAAYKASLAEAEQEKLNQIKAKLKQQELRAELSAIRQKQSGFKSSRSSTQEKINALDANLKAAEQNNSRGRFKSVEEIDNQI-ARLEKEVDSGTLRLVDERKALTEVSNLRKQRKSFAGLDEAQKGINDIKTQISELRK-TLD--NPEAKALSDKYSEIQKELDAIKAEQDNLNALRDERTKLRNEQQEKYTAIRTARRAYKEYEDEAWRVRRERQKAEQAREKRADKKLEEASQLADEILTAQGLIRHFFNMNVGIIEDFAKVKIDPPMNQSDVPASVEKLAAKWKKNQ-ASKTEENIKKAQEE Phybl2 ---------------------------------------------------------------------------------------------------------MLQEISLLKRSRQQVEDLDEQQAAIDREKTIHAEIKK-NID--DGDAKKYSEQFETLNAEYKQLNEEGFARNKLFDERTRLRGLLDEEFNALRTANDEYYNFIRQLREHKREQERLRKEAEQRAEQELELASMPAHEIALCENLAKYLLKLPLSTLEDFFLVKVTVPTKITEVAVTLEKLKERYLSEQ-PKVTESNKQKAIAK Picst3 RPDDKALKEEIEGLKDLANNELTAQIKRSKLQEELKSLIQQQSASKNERNAINDQIKNIDGQMKKAEIQAQTSKFKTVGEIDSRI-SYLDGLIDAGDLKLADERRFVKEMSALRKLRKDFGGIEKTQSLIDADKVKIADLKK-KLL--SFQNKELSARFDAIQKELDTINEANKKRLTLFDKRTEIKKQKDEKYNQIRKQFAKFKLTLAEEKKKRDEEYKQRQKQAKRAEQQLAEASVPATEINSIHNLLSYFFTVDPDVIVSLSDLSIPFPTKEEEVTSTVEVLKETLEDKQ-EEQTKTNIERAKAR Plicr1 RPDKALYDAEQEKIKQVKLSAVREKIRRAVLRAELDSIRGQQSNNKNSRGKVIEQLKSLQDGIQKKDLQAAKAKFKTVAEVDNHI-KHLEKQVESGNMKLVDEKRALQEISQTKRSRRNVEAFQADQEAIEADRRAADELRK-ELD--DPESKAVSERYDAIKAELDELKKEGDGRSKLFEERDGLQAQLNTLYNKKREANDRFYTKLNEDRARRAERARAQREAEKKAERLREEAAAPAAFIEDCQTLIDYFLNVPLPTLSALLTLSIPPPTSSADVPRVVEDLKTKYEANQ-ARVTAENVAKAEAE Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RPSKDAYSQEQDQYKQSEISELRLKIRRKALRDEMDALRQEQSKGKSSRGKLLDQIKAANDSVQRKELNANRAKYKSSVEVDAKI-RQLESQIESGTMRIVEEKKALTEIQNLRKARKLVDAFGPQQELIEAEKEQIEELRK-QLD--DPHNKSTNDRWSEIKRELDQINEQLDSRDKLFEERNKLQDALTEVFNKKREANEKYYAKMQEDQQRRIDRQKAEREKAEIHIEMREQAALPAREIEDCRTLILHFLNLPLSTINALYALAVPVPMTREDVVKTIATLSEKFTENQ-ARVTKERIAETEAK Punst1 RPDKAVYDAEQEKLKQTKLAAVKEKIRRTKLRAELDEIRGQQANGKTSRGKIHDQLNVLNESIQKKDLNAAKSRFKTVAEVDAHI-KNLEARVESGSMKITEEKKAIQEISQSKRARKTVESFQQEQEAIDASRAAADELRK-QLD--DPEVAAISQRYASIKAQLEELKKEADNRNKLFDERNALQAELDVLHNQRREANDRFYAKLAEDRARRAERARAEREEEKKAEKLREEASIPAAEIEDCQTLIDQFLNVPMPTLHALFALAIPPPTSPDEVPRVIKDLKTKFEANQ-ARVTTENIAKAEAE Rhior3 KPMEEEFKKTIESINQKQFDAVKEKIRREEIKSELAEIREKQAELKKSRKAVYEQLDALNESIRKSVVKGFQSKYRSTEEVDDRI-AELERKIEAGV-RIVEEKKMLQEISLLKRNRLSFEDIDQQQTEIDRERAIYDELKK-NID--DSEAKKLSDRYEQLDAEFKEIHGDQTARNKLYDERTRLKGLLDEEYNKLRTNNDEYYAFVRKLREYKKEQEQLRKENEKRAKQELELASLPANEIALCDNLVIFLLKLPLATMENFFDIKVTVPTKISEIPATIQKLKERFIKEQ-PKVTEANKKKAEER Rhoto1 RPDKKAYDDEQNELRQAKANDLRNKIRKLAIRKEMDELRAEQAKGKGGREKTLEKLKQMQDALKRDDMTSARSKYKTVQDVDNQI-KSLERQVESGSMKLVDEKKALSEISSLRKSRKVVESFAAQQAAIDADKAKIDEVRK-ELD--DPEQKAVSKKMGELRKELDEINKKFDNRDGLFEERNAISKQLDELFDKKKAANNKYYKKIEEDRQKRDERRKAEREDSKRNQRLLEEAQAPAREIEDCKTLIRFFLNLPFGTLTALMTLGITAPLTTGEVQKTIDSLQLKFTDNQ-DRVTKERIAAVEAK Rozal11 AAPKSAFLVQKDKFYEEK---IKTKVKSSVVREEIKKLMLEKKNKMKEIEELEQEYELVEKDIEENEINKAKEKYKNTEEIDRRINRELEVMIESQSFSLKQEKSLLQDISKLTKAKKDFEQFK--NTTVNEHKPKINLLKE-KLNDVLTRLRQARKERSQIIEKLKPLQSVRD--NVFYERREKNNKEIERL------EKQDIYQELQEFKKKNENKIKLEKEMLNKVERKIEETQKSVEQIIKCKNLIQFFFTLPMWVIAGLSEVVVAVPTSVNDIPTCVEKLNSQYGEQA-KKDSIANAQKIKDL Sacce1 RPDVSVRDKKLDTLNDTEIGLIRKQIERKKLQDKNKEIIKIQADLKTRRSNIHDSIKQLDAQIKRNQIEEKLGKFSSTAEAKQRI-NEIEESIASGDLSLVQEKLLVKEMQSLNKLIKDLVNIEPIRKSVDADKAKINQLKE-ELN--GLNPKDVSNQFEENQQKLNDIHSKTQKRQTLFNKRAALYKKRDELYSQIRQEFKSFRAKLDKERLKREEEQRLSKQKDVDLQEKLTHAKIPAYEIGAIENSLLVLFTLEPTLIATLAELDVTVPINSDDVKITVEQLKKKLLSKQ-EEQTKQNIESVEKE Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 KPDKAAYDAEQENIKQLKLNVVRDKIRRKVLRDELDEIRGQQSDNKASRGKILDQVKTIQDGIQKKDLNAAKQKFKTVAEVDTHV-RNLEKQVESGNMRVVDEKRALQEIQQLKRSRRTVESFQADQESIEADRAKLDELRK-QLD--DPEFKAISDRYDTIKAELDEIKKVDDNRSKLFAERDELQAQINALYNQKREANDRYWTKVNEDRARRAERARAQRELAKKARRLREEAEIPAAEIEDCQTLIDYFLHVPFATLSALLALSIPPPANHGDVPRVIEDLGTKFEANQ-KRVTAENVARAEAE Schpo1 RPNEALHKEALEELDKKRFNEHKEKLKNAELRAELDNIRNAQAAIRSSKQTLINKVKAQDELLKKKELTAMKKTFKSEVELDKHV-KQLQAAVDSGTLKIVDEKKYLREISQCNRTRKSFVELNALQTSIDTIRNELNELRD-QLN--DSESKKLSDKFVEIRSELDEVRKQQDDQRKLIAERDDEKTALDDLYNQRRAQLRAFRTYEREQRAKRQEQFRLEREKEKRAQRKLEEASIPAEEILACENLLKVFLNLSFGTIKEFDFVGVPAPFTKSQVDSAVEQLKSRFKEQQ-DSVTKQRIEKAKQE Sorma KPDQDAFNEKLAQAELKKYNEVKAKVKRQELISQLNEIRQQQAGGKNARTSKLDQIKRLDEQLRSAEQKTARSKFKSTEELDREI-ERLEKEVNGGMMKLVDEKKALAEISNLRKQRKSFAGFDDAQKQIDVLKAKIKEIKD-SLE--DPEAKALSEKYNKLQAELDAIKAEQDNLSSLRDERTKLQQLQSEKYQAIKKAKKEFAKWEREQREKYRERQQAERAKERRAQKMLAEASDPAEEIRRANSLLKYFFSLPPSVMEDCSFVGVEPPMAAADIPAAVEKIKAKWKADQ-PEQTRKNIEKAKKE Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 KPDQATFERELKEIDKKQLAEAQNRIRRKDLREQQDALIKQRNELQDQRGKIFDQLKAIQAKLRKDDARSSKDRYKSVEDVDKQI-STLERQLQSGEASLHEEKRIVAEISNLKKARKILEGFSSQQSSVESDKKQLDDLRA-QLDAIEPQRKEIHAKIDAVKAQFTDLDNERKNLNDLVNDRKNIKADLDAEFDKLRAQKDEWFTWQREEHARKHEQYLARKSEARLAEREREAAEIPADEINQCATLIKFLFKLDFDIIDQFVKLKIDLPVSAAEIPATISALEEKFKDNQ-AEATAKAKAAAEAK Sporo1 --------PEQDDLRQTKVNDIRNKIRKIELRKQLDELRTEQQKLRGGRGKTVEQLGQMQEQLKKSELQTAKAKYKTVQDVDDRI-KNLDRQVESGTMKLVEEKKALSEISSLRKSRKTVESFGTLQSSIDADKKKVDEVRA-LLD--DPEQKKLDEQSKSLKRELDEVNKKMDSRDALFDERNTLSQQLDELFTKKKAANNKYYEKIHADRAKRDEKRREEREASKRNQQLLEEAQAPAREIEDCRNLILFFLNLPFGTLAALMGLGITAPLTTKDVPQTIDNLELKFVDNQ-SRVTKERVAAVE-- Stehi1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 KPDEDEFKKNLSKAENDNLNKVRAKIKTQELKKQLDSIKEKQASIKGSKAKVFEQVRSLEESIKRADSQASKKKYKSSAEIDSKI-AELEKQVDSGKLKLVDEKKYLQEISQLKRAKKSFTEANSSQSSIDAEKKQVEELRK-QID--DPESKALSKQYDEVKAELDSLRGEQDSRQKLYDERNSLSAKSKEIYLNIKGGKKASIAYEKDQRQKRYDAQKAEREKQKRANKKMEEAREPAVEIMTCNNLIRYFFNLSIGTIQELGTVNVQAPLNASEVPSTVEKLKEKYKSHQ-AAETEKRVAKAQKE Thetr KPDFDKLKEEEAVIQHEELRRIKAELTRDKEQQVLKDIHKQQKKLQGARREIVGRIEEQRARNKKASQEALRRHYNTVEKIESRI-AALESAIETTASSLRDERELLAQITALKRDRTAVVEYEALTAAVAANKAALDPLYE-ELRAKEAEIKELKAVESEQHSTVVSLRNRIKNSPSLWKQRKEVKSKLDALYDARRKSKKAYSKYWNELKKWKDEMFAARREAERKAAEAAARAEDERAEMKICSALIGYLLSMAPQVMADFAKVGLEAPLELDAVPAAIDALVARYKDGKPPKIAKAAGAKAKAG Treme1 KPDQAKYNAEQDGYNKTKQDSVRARIRRSQLKIEMDSLRSEQGKYKSERQKTLDELKKLQEIVGKKDAQGTKSKFRSVNEVEERI-SALNAQVESGTMKLVDERKALAELSTLRRSRKALESSGSVEDSIAADRARIDELRK-ILD--DPEVKKITDKYDELKKESDGLREEGDERNKLFDERNALSAQLDEIYKKKREENDRYYAKIQADQKARQDRLKAERDAIKRIVRLREEAKIPASEIDDCQVLINWFVNLPMSLLTALLSLGIPPPTGKDDVQRTMNDLETKYEANS-ATKT---------- Trire2 RPDENAFKEALAKAEMDKFNAIKAKIRRQELIAQANEIRQKQAGGKNARTSKLDQIKRLDEQLRSNEQKAAKAKFKSVEDVDRQI-EALDKQVNSGTMKL----------------------------QIDDLRAKIKEIKD-SME--DPEQKALSEQYNKIQAELDVIKAEQDNLSSLRDERTKLQAEQQEKFAAIRKQKKAYQAYEREAREKQRERQRLERVQERKAERVLAEASEPADEIRRANSLLAFLFNCPPSVVEDCAFLSLDPPMREEDVPELVEKVKAKWKEDQ-AAQTQRNIEKAKKK Umbra1 KPDDAALKKNLGEIQKKQNDAVREKVKREELFTKLNQVRDQQKELKDSKKAVLTQLDVIQQSMKKAALKAGQSKFKTTADVDRQI-SILEKRIESGV-KLVEEK----QISTLKRHKNTIDSFKDQQTELDKERKIYEDLKK-NID--DSQMRSLNQEFDAIKLELNDIQESQKKRNQLYEEQNSIKAQLDQQYEKMRTAMDEH------------------------------------HQ------------------------------------------------------------------ Ustma22 KPDAAANTAELDKLAQKELNQVRSLLRRAELRSQLDELRNQQAGSKGARGKTLEDLRSLQENIAKKDLQHAKSKYKSTADVDSRI-KRLEEQVESGSMKLVEEKKALSEISQLKKNRKVVENFDAMQASIDADRAKVDQLKS-TLD--SPEAKALNKKYDDIKSELDAIQAEQDSRGKLLDQRTQLSAQLDALYQSRRDANDTFYAKLNQERERRLAKQREEREAEKKAAQLREEAAMPAKEIEDCDVLINYFLNVPLGTLSALLALSIPPPVNAADVARVVENLKLKFVSNQ-ARVTKENIDKVEKL Walse1 KPDTTEYKNQQDAFKQLKLQAVRQKIRRKALFNELNELKLHQSGNNASRGKVIDRIRVLQDSMQKKDLQASKSKFKTVDAIDDRV-TSLDGEIESGTLRLADEKRALQEISNLRRHRKVVEGFAQQQQAIDADRAQIDALKL-HLD--DPESKALNDKAEEIKKGLTQAKVEIDSRQTLFDQRNKLQADLDAVYAEKRETMDAYYQKVNEDKARRAQRAKEEREAQKAAEQIREDAKLPAAQIQDCQTLIDQFLNVPLATLTALMGLSIPPPKSQSEIQTTVESLEIKYEANQ-AKQTKENVEKAEKE Zygro1 RPDVSVRDKKLDVYNDGEIAVLRKQIERKKLQEQTREIIKTQADLKSRRNAIHERVKQLDANIKRGEINEKLGRYSTTAEVKQRI-NEIEEAISSGDLTLVDEKRLVKEMQALNKLNKDLVAVEPVKKSIENDKQQIASLKE-ELS--QLNPREVSDKFEQTQEKLNSLQSKTQKRQTLFNKRTALYKKRDEIYAQIKKEFKAYKQKLEKDRLKREEDQKLSKEKDAKLQEKLAHAKLPASEIGTIENALFVLFTLEPTLIAALAELEVTVPISQDQVSTTVDQLKEKYTSKQ-DEQTEKNIEQVEKQ [Cluster2886.fasta_al_trimmed; alignment length = 54] Allma1 IRLARIGRNNPLYRVVVANAKRDGKPLEAVGMYNPVPYWLS-V-GAQPTVKKLL Ashgo11 IRLARFGRHSPVYNIVVANAHTTRKPIEVIGTYDPIPYWIG-V-GAQPSVTRLL Aspfu1 IRLSRFGRHQPFYNIVVAHARRDSKPLEVIGTYNPIPYWLG-V-GAQPSVWRLL Aurde31 LRFAVHGRNNRIFHLVAIDQRRNARPLELLGVYRPRIFWLD-H-GAVPSVTRML Batde5 IRLARWGANNPFYGIVVANLRRDGKHLERLGTYNPISYWLS-V-GAQPSVAWLL Botbo1 IRLARPPKSTTQLHLVAVNARRDAKPLEVLGVYDPVPYWLG-V-GAQPSVVRLL Botci1 ------------------------------------------------------ Caeel IGLALFGTNRPFYHVCVFPDRYEGNILEQVGTFDPLPYWIGER-NAHISVLELL Canalb1 IRLARFGKHQPIYNIVVMKAKQQKLPMEVIGTYNPIPYWLG-M-GAVPTVTWLL Cangl IRLARFGVNSPLYNIVVARSHRDAKPIEVLGTYNPVPYWIG-V-GAQPSVVRLF Capow LRLARFGIHHPVYRIVVGERGRDGKHLEHVGTYHPEPYWLS-V-GAQPTVGKLL Catan2 IRLARIGRNNPLFRVVVANNKRDGLPLEAVGMYNPVPYWLS-V-GAQPTVKKML Cioin IRLALSGTNRPFYRIVLSRKMTE---IEQLGSFDPFPHHLA-L-GAYVGVRRLL CocheC53 IRLARFGKHSPFYNIVVAHARRNGRPLEVLGTYDPTPYWVG-V-GAQPSAWRIL Coere1 IRFARHGRNRPFYHIVAMVGRRDGKPLEKLGTYDPLPYWLG-V-GAQPSVRFLL Conco1 ------------------------------------------------------ Conpu1 IRLAMHGRSRRIFHLVAIDQRRDAKPAELLGVYNPHLYWLG-V-GAVPSAVRML Copci MRMSVHGTNYRIFHINVVEGTRDAKPTELLGVYDPHVYWLS-V-GAKPSVLKLL Croqu1 ------------------------------------------------------ CryneH991 IRFARHGRKNPVFHLVAINSKRDGKPLELLGVYDPIPYWLG-V-GAQPTAVKLL Crypa2 LRLARFGTNAPFYNIVVAHARRNSKPLEVIGTYDPIPYWIG-V-GAQPTVWRFL Debha1 IRLALFGKNQPLYNIVVANKRRDSLPIEVLGTYNPISYWIG-V-GADLSVNFLF Dekbr2 IRLARMGVHQPIYNIVVTNKRRDGKPIEIIGTYNPVPYWLG-V-GAQPTIAKLF Dicdi ------------------------------------------------------ Dmel IRFVRLGTNRPFYHIVVMERRQHQPVIEQVGSFDPLPYWLG-K-GAHLSAAELL Enthi ------------------------------------------------------ Falba ------------------------------------------------------ Fomme1 ------------------------------------------------------ Fusgr1 IRLARFGRNQPFYNIVVAHARRNSRPLEVIGTYDPIPYWIG-V-GAQPTAWRLL Galma1 LRMAMHGRHHKIFHLVAINSKRNAKPKELLGIYDPHAHWLS-V-GAQPSVARLL Ganpr1 IRLARWGRHNPFYGIVVAEARRDGRHIERIGTYNPIPYWIA-N-GAHPTVGWLL Gloin1 IRLARHGRNRPFYNIVVANAKRDGKHIEKVGLYDPIPYWLN-V-GAWPSVARLL Hisca1 IRLSRFGRHQPFYNIVVAQARRDSKPLEVIGTYSPIPYWLG-V-GAQPSVWRLL Klula1 IRLARFGKHTPVYNIVVTNKHLNRKPIEVLGTYNPIPYWIG-V-GAQPSVTRLL Lacbi2 LRMSVHGTNHRIFHLVAIDRRRDGKPTELLGIYDPHLYWLD-V-GATPSVVKLL Lenti61 LRMAVHGRNSRIFHIVAVNQRRNAKPIELLGVYDPRLYWLN-V-GATPSVTKLL Malgl1 LRLARHGRNNPFYHVVAIQNTRDARPIEKLGEYDPVPYWLN-T-GAQPSVARLL Mellp23 ------------------------------------------------------ Mnele IRLIRPTRNRPGYQMVACYGPRKSSIIEEVGYFDDCVQYIA-L-GAEPTVWKLL Monbr LRLQRFGRHRPFFRIVAADQRRDGKHLERLGTYDPIPYFAR-L-GARRSLFRLK Morel2 IKLARHGKNTPFYHIVVLQSRPTRKPIEQLGTYNPIPYWIG-V-GAKPSVARIL Mucci2 IRLARHGRNLPFYHIVVANARRNSKPIEKIGTYNPVAYWLT-V-GAQPSVEKLL Mydma LRLAYYGPNRPFFHIVATKQRRNRGYYEQVGTFDPLPYWLS-L-NCSMSVTRLL Neucr2 LRLARFGTNAPFYNIVVAHARRNSKPLEVIGTYDPVPYWIG-V-GAQPTVWRLL Orpsp11 ------------------------------------------------------ Pench1 IRLARFGKHNPFFNIVVAQARRGAKPLEVIGTYNPIPYWLG-V-GAQPSVWKLM Phybl2 IRLARHGRNLPYYHIVVANSRRNAKPLEKIGTYNPLPYWLT-V-GAQPSVEKLL Picst3 IRLARFGKHQPLYNIVVANRGRDALPIEVLGTYNPNPYWLG-V-GADVSVSYLF Plicr1 IRFAMHGRNRRIFHLVAIDLRRDAKPMELLGIYNPHLYWLN-V-GAQPSAVKLL Polpo ------------------------------------------------------ Pucgr2 ------------------------------------------------------ Punst1 ------------------------------------------------------ Rhior3 IRLARHGRNLPFYQIVVANARRNSKPIEKIGSYNPIPYWLT-V-GAQPSVEKLL Rhoto1 LRLARHHRNNPVYSLVAIRAPQTAKPLELLGSYNPRPYWLS-Q-GALPTFEKLL Rozal11 IRMQQLGTKARFYRIVVAPKERNGKFIEELGSYEPYPYWLG-N-GAQPMVRKLL Sacce1 IRLARFGKNSPVYNIVVANSRRDAKPIEVLGTYVPVPYWIG-V-GAQPSVTKLL Salro MRLQRFGRHSPFYRIVVANRRRDGKFIERVGTYNPFPYWLS-V-GAQPSVSYLL Schco3 IRLAMHGRNHRIFHLVAINSDRNARPTELLGIYDPHLYWLS-V-GAQPTAVKLL Schpo1 IRLARHGRNRPFYHIVVANAWPQAKPIETIGTFDPIPYWIS-V-GAQPSVRSLA Sorma LRLARFGRNAPVYNVVVAHARRNSKPLEVIGTYDPIPYWIG-V-GAQPTVRRLL Sphar IHVSPFS--------VVADGRRDGKFIEHVGTYEAIPYWIS-V-GAQPTVARLL Spipu1 IRLARWGSHNPFYGIVVANHRRDGKHLERVGTYNVIPYWLG-V-GAQPTVAWLL Sporo1 IRLARQHRNSPSYTLVATRASPTAKPLETLGSYSPLPYWLS-I-GAKPSVERLL Stehi1 IRFAMHGRNNRILHLVAIHGTRNAKPIETLAVYNPHVYWLE-IAGAEPSAVRLL Tapde11 IRLQRFGKKLPFYHIVCMNARRNSKPLEKLGTYDPIPYWLG-V-GAQPTAARLL Thetr ------------------------------------------------------ Treme1 LRLARHGRNTPFYHIVAIQNHRNALPIETLGIYDPIPYWLS-V-GAQPTVIKLL Trire2 IRLARFGRNSPFYNIVVAHARRNSRPLEVIGTYDPIPYWIG-V-GAQPTAWRLL Umbra1 LRFARHGRNLPYYHIVAANAKRNSKPLETIGTYNPIPYWLT-V-GAQPSVASLL Ustma22 LRLSRKGRNNPFYHVVAINDSRDARPIEKLGEFDPIPHWLK-L-GAQPSVARLL Walse1 LRLARHGANRPFYHIVAIPAQRNGQPLEKLGEYDPTPYWLS-V-GALPTVTKLL Zygro1 IRLARFGVNNPVYNIVVARAFRDTKPIEVLGTYNPVPYWIG-V-GAQPSVTSLL [Cluster2889.fasta_al_trimmed; alignment length = 48] Allma1 LKDNSFSYGEKAHRDLIVTRGKGFRHEKNKKKRGSYRGGAIDSI--KF Ashgo11 LTDNTYTWGEKANDKLSRVRGKDFTKNKNKMKRGSYRGGSITSY--KF Aspfu1 HPSNAYAYAEKAWKDLSVTRGKGFTKEKNKKKRGSYRGGPIDSF--KF Aurde31 LKDNTFDYGEKASQDLIVTRGAGFRKEKNKKKRGSYRGGEITSI--KF Batde5 LKDNRFDYGYKAHMDLIVTRGKGFTKEKNKKKRGSYRGGVINSI--KF Botbo1 LKDNSFDYGERASRDLIVTRGAGFRKEKNKKKRGSYHGGEITSI--KF Botci1 LSSNAFDYAQKAHEDLIVTKGKGFTKEKNKKKRGSYRGGFIDGI--KF Caeel ------------------------------------------------ Canalb1 LQDNTYTWGEKASEKLLQVRGKDFTKNKNKMKRGSYKGGSITSY--KF Cangl LTDNTYTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRGGTITSY--KF Capow LADNSYAFGERANNILKFTKGKSFRHEKTKKKRGGYKGGSIDSI--MY Catan2 VKDNSYSYGDRAHRDLVVTRGKSFRAEKTKKKRGSYRGGVIDCI--KL Cioin ------------------------------------------------ CocheC53 LASNAYDYADRAHAKLIVTKGKGFTKEKNKGKRGSYRGGMIDGI--KF Coere1 --------------DLIVTRGKAFTKEKNKKKRGSYSGGRITSI--KF Conco1 LKDNTFSYGMKAHEDLIVTKGKGFTKEKNKKKRGSYRGGQIDSI--KF Conpu1 WINNAYDYGERASKDLIVTRGQGFRKEKNKKKRGSYRGGEIT------ Copci TFDNRYDYGQKAHQDLIVTRGAGFRKEKNKKKRGSYKGGEITSF--KF Croqu1 VADNGFSYGHKAHMDLIVTRGKAFTKEKNKKKRGSYRGGIIDSI--KF CryneH991 LMDNSFDYGAKASRDLIVTRGAGFRKEKNKKKRGSYVGGEITSI--KF Crypa2 ------------------------------------------------ Debha1 LADNTYSWGEIANEKLLQVRGKDFTKNKNKMKKGSYKGGSITSY--KF Dekbr2 LMDNSYNWGERAAEKLGRVRGKDFTKNKNKMKRGGYKGGIITSY--KF Dicdi ------------------------------------------------ Dmel ------------------------------------------------ Enthi ------------------------------------------------ Falba LRDNSYSYGFKANAALERTRGKGFRHEKTKKKRGSYRGGNIDSF--RF Fomme1 LKDNSYDYGAKANADLIVTRGDGFRKEKNKKKRGSYRGGEISSI--KF Fusgr1 FASNEYAYSQRAHEDLIVTKGKGFTKEKNKKKRGSYRGGAIDGI--YF Galma1 IANNQYDYGKRAHEDLIVTRGAGFRKEKNKKKKGSYRGGEITSF--KF Ganpr1 LKDNTYDYGFKAHKDLIVTRGKGFRAEKTKKKRGSYRGGAIDSI--KF Gloin1 LKDNSFSYGYKAHNDLFATRGKDFRAQKTKKKRGSYRGGKIDSI--KF Hisca1 HPSNAYAYAERAYKDLSVTRGKGFTKEKNKKKRGSYRGGLIDSF--KF Klula1 LTDNTYTWGEMANDKLSRVRGKDFTKNKNKMKRGSYRGGSITSY--KF Lacbi2 FVDNRYDYGSRAHSDLIVTRGAGFRKEKNKKKRGSYRGGEITSF--KF Lenti61 LKDNRFDYGARASRDLIVTRGAGFRKEKNKKKRGSYHGGEITSI--KF Malgl1 ------------------------------------------------ Mellp23 VADNSFSYGHKAHMDLIVTRGKAFTKEKNKKKRGSYRGGIIDSI--KF Mnele LADNAFEYGYKANQILKFTKGKSFRHEKTKKKRGTYKGGAINSI--KF Monbr ------------------------------------------------ Morel2 LKDNTYGYGYKAHLDMIVTKGKGFRAEKTKKKRGSYKGGLIDSF--KF Mucci2 LKDNTYSYGWKASQDLIKVRGDKFRAEKNKKKRGSYRGGQISSI--KF Mydma LRNNSFDWGEKANQDLKFTRGKGFRHEKTKKKRGSYRGGAINSI--KF Neucr2 LASNAFEWGQKAHEDLIVTRGKGFTKEKNKKKRGSYRGGRIDGI--KF Orpsp11 ------------------------------------------------ Pench1 HPSNDYAYAERAWKDLSVTRGKGFTKEKNKKKRGSYRGGPIDSF--KF Phybl2 LKDNSYSYGWKAHVDLIKTRGDKFRAEKNKKKRGAYRGGAITSI--KF Picst3 LQDNTYTWGEVANSKLGAVRGKDFTKNKNKMKRGAYKGGSITSY--KF Plicr1 IQDNRYDYGERAHRDLIVTRGAGFRKEKNKKKRGSYKGGEITSF--KF Polpo ------------------------------------------------ Pucgr2 VSDNSFSYGYKAHQDLIVTRGKAFTKEKNKKKRGSYRGGIIDSI--KF Punst1 ------DYGARASKDLIVTRGDGFRKEKNKKKRGSYRGGEITPVIRYF Rhior3 LKDNTYSYGWKASQDLIKVRGDKFRAEKNKKKRGSYRGGQISSI--KF Rhoto1 LKDMSFDYGAKASADLIVTRGKGFTKEKNKKKRGSYRGGEITSI--KF Rozal11 LKDNSFSYGEKANEKLSKVRGKDFRHEKNKKKRGSYKGGEIDSI--AF Sacce1 LTDNTYTWGEKANEKLGRVRGKDFTKNKNKMKRGSYRGGSITSY--KF Salro LADNSYGWGARAAEQLKVTRGKSFRHEKTKKKRGSYRGGQIDSF--TF Schco3 ------DYGARAHQDLIVTRGAGFRKEKNKKKRGSYRGGDITQV--HL Schpo1 LRDNSFDYGTLANRDLIVTRGKGFRQEKNKKKRGSYRGGRINSF--KF Sorma LASNAFAWGQKAHEDLIVTRGKGFTKEKNKKKRGSYRGGPIDSI--KF Sphar LWNNAYSWGAKASEDLLKVRGKGFTREKNKKKRGAYRGGEIDSI--KF Spipu1 IINNAYSYGLKAHQDLIVTRGKGFRNEKNKKKRGSYRGGRIDSV--KF Sporo1 ------------------------------------------------ Stehi1 LKDNTFDYGARASSDLIVTRGDGFRKEKNKKKRGSYKGGDITSF--KF Tapde11 ------------------------------------------------ Thetr LRDNSYSYGARAFEEMVHTRGKGFTKVKNKRKN-SYRGGNINSY--IF Treme1 LKDNSFDYGARASRDLIVTRGAGFRKEKNKKKRGSYAGGEITSI--KF Trire2 FASNEYSYSQRAHEDLIVTKGKGFTKEKNKKKKGSFRGGPIDSI--YF Umbra1 --DNSYSYGWKAHQDLIVTRGDKFRAEKNKKKRGSYRGGQIDSI--KF Ustma22 MRDMSYEYGARASRDLIVTRGKGFTKEKNKKKRGSYRGGAIDSI--KF Walse1 LADNSFDFGHKAAADLAPTKGAGFRKEKNKKKRGSYKGGEIFSI---- Zygro1 LTDNTYTWGEQANEKLSRVRGKDFTKNKNKLKKGSYRGGSITSY--KF [Cluster2890.fasta_al_trimmed; alignment length = 114] Allma1 TLQV-FRDVLPP-RPSARGYRAQDW-DVWRGRLRVLQ-EDTTTLFGEAILVEPVIDSSRYFVVRLSDHAFVGMGFAERSDAFDLNVALMDFEKP----DLALKDGQQIAINLGN Ashgo11 ------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------ Aurde31 IIYM-CREVIPP-RTKNEGYKAQEWGDLWKGRLRLIE-EDATTIFAQSPYVEAVLDSSRYFVLRVEDKAYIGLGFAERPDAFDFNVALQDYDKVAK--DFTLKEGQTFSVRIPG Batde5 VLCV-IKECIPP-RATAKGYRASEW-DLWSGRLRVIA-EDPVTLFAKCPYVEPVIDSSRYFVIRVVDHAFLGLGVAERSWAFDLNVALQDHTK--------------------- Botbo1 ILFV-CREVVPP-RASNAGYRAQDWGDLWKGRMRIVE-EDATTVFAQAPYVEATLDSSRYFVLRVEDKAYIGVGFTERTESFDFNVALQDYTKPKK--DYSLQPGQTFSINIPH Botci1 ILFI-APSVIPP-LTSNKGYVAATWTAIFTARVRILE-EDPSNLFAAAPYVEQVLDSSRFFAVRVQGKAVLGIGFEERSEAFDFSVALQEVRKVKR--DFSLKEGETITVNIGG Caeel VLMV-KPKVIPP--IGTSGHKAADW-NAWTGRMRLVA-EDGETLYAKCPIIEAVSDSSRYFVIRLQNQAFVGCGFQERGDAFDFNVTLQDHFRPSL--DLAFKEGQTISINIGK Canalb1 ------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------ Capow TVMQ-KQECLPP-RPSNRGFRAADW-DIWSGRIKVVT-EDKSTLFAPCPVVEAVIDSSRYFVLRIVDHAFIGLGFADRGDSFDLQVALQDHFKPQPSLDLGFKAGEKLHIN--- Catan2 TLLV-KREALPP-RSSAQGYKAASW-DAWTGRLRILH-EDATSLFGESLIVERVLDSSRYFVIKLVDSAFAGFGFADRADAFDFNVALQDFGKPPM--DFGLKDGQQIKLNIGG Cioin TLMV-KNECLPP-RPSNRGYRAADW-GMWTGRMRVTT-LS-NELFAEAPVVESVTDSSRYFILRIINKAFIGTGFADRGDAFDFNVTLQDHFKS---LDLGLKAGQTFRINIGN CocheC53 ILYL-APKVIPP-ATSTKGYQASTWTAIFTARLRIVE-EDPKNLFAAAPYVEQALDSSRFFAITVVGKAVLGMGFEERSEAFDFSIALQDARRAKR--DFSLKAGETISINLGG Coere1 ------------------------------------------------------------------------------------------------------------------ Conco1 VLLT-VKECLPP-RVKSEGYKAGEW-GLWQGRLRIIS-EDGNSLFASCPYVEPVLDSSRYFVIRVEDHAFLGLGFQDRSEAFDFNVALQDFLKPEQIIDYSLKEGETINLSLGG Conpu1 ILHI-AREVIPP-LRKNEGHRANEWGDLWKGRMRIVE-EDGTTLFAKAEYVEAVLDSSRYFVVRVEEKAYIGMGFAERTDSFDFNVALQDYTKPKK--DYSLKEGQTFSINIPG Copci ILHI-AREVIPP-LSTNAGHRAGEWGDLWKGRLRIIE-EDSQTLFAKTPYVEAVLDSSRYFVVRVEDKAYIGMGFVERTDSFDFNVALQDYSKPKK--DYTLKEGQTFSISIPG Croqu1 VLWV-GRECLPP-RTSTAGYKAAEWGDLWKGRCRVIE-EDLDTLFANCPYVEPVLDSSRYYVIRVEDRAFLGMGFPERSDSFDFNVALQDWVKPKR--DFSLKEGQTISISLGG CryneH991 VLFV-AREVIPP-RTTTAGYKAAEW-NLWKGRMRVLD-EDSNTLFAQVNYVEPVLDSSRYFVLRVEGRAYIGMGFAERGESFDFQVALQSVTKPPK--DYSLKDGQTFTIKIPG Crypa2 ILFI-SMNVIPP-LTSTKGHMAAHWTDISTCRLRVIE-EDLSTLFAAAPYVEPTLDSSRFFAVRVQDKATLGIGFEERSEAFDFGVALQDAQKEKR--DLSLKEGETITVNLGG Debha1 ------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------ Dicdi TLLV-KKECIPP-RPSASGYKAQDW-DIWTGRLVIVA-EDPNNIFAQCPFVEPVVDSSRYFVIRIKDHAFVGMGFTDRDDAFEFNATLQDHQNPKK--DYSLKTGQTIHIPF-- Dmel VLIV-KPEVIPP-RASNRGYRAGDW-NTWTGRMRLVA-EDKTSLFANCPIIEAVSDSSRYFVIRVQDSAFLGLGFGDRSDSFDLNVALQDHFKPKQELDLGFKEGETIKINMR- Enthi ILLV-INQCIKPMTSPNMKYKAGEW-TLWQGKCVVVA-VDSNTTFAQCPVVEPVIDSSRYFVVRIVDKAFLGMGFQERSEAFDFTVALQDFERPIDMSAFELKPGQTITLNIKS Falba ------------------------------------------------------------------------------------------------------------------ Fomme1 ILYI-CREVIPP-LKANEGHRAQDWGDLWKGRLRIVE-EDPTTLFAKTPYVEAVLDSSRYFVVRLEDKAYIGMGFAERTDSFDFNVSLQDYTKPKK--DYTLKEGQTFSISIPG Fusgr1 ILFV-ANAVIPP-LTSTKGYSASTWTAIFTARLRVVE-EDASTLFAAAPYVEPVLDSSRFFALTVRDKAILGIGFEERSEAFDLSIALQEARKEHK--DYSLKEGETITVSFGG Galma1 ILYI-AREIIPP-LNANEGYRANDWGDLWKGRLRIIE-EDAQTLFARAEYVEAVLDSSRYFVVRVEDKAYIGLGFAERTDSFDFNVALQDYTKPKK--DYSLKEGQTFSISIPG Ganpr1 VLTV-IRQALPP-RTTAKGYRAADWD-LWQGRVKIFT-EDGTTLFAQCPYVEPVTDSSRYFVVKVVDHAFIGLGFQERSDSFDFNVVLQDFERPKV--DFSLKEGETISINIGG Gloin1 VLLV-IRECIPP-RTSSREYKASEWGDLWKGRLRVIS-EDGTTLFAQCLYVEPVRDSSRYFVLRIEDHAFIGMGFQERSEAFDFQVALQDHVKPKR--DYSLKEGQTIRLKIGN Hisca1 VLFI-CHPVIPP-LTSMKGYSAADWTVIFTARLRIIE-EDPSTLFAAAPYVEHAVDSSRFFALRVMNKAILGIGFEDRSEAFDFGVTLQEARKPPR--DYSLKPGETISINIGG Klula1 ------------------------------------------------------------------------------------------------------------------ Lacbi2 ILYI-AREIIPP-LKANEGHRANEWGDLWKGRLRIIE-EDAQTIFAKAEYVEAVLDSSRYFVVRVEDKAYIGIGFAERTDSFDFNVALQDYEKPKK--DYSLKEGQTFSIAIPG Lenti61 ILYI-GREVIPP-LKANEGHRAQEWGDLWKGRIRIIE-EDATTVFAKADYVEAVLDSSRYFVVRVEDRAYIGMGFLERSDSFDFNVALQDYTKPKK--DYTLKEGQTFSISIPG Malgl1 TLFL-VQTCVPP-RTSAAGYRAAEWGDLWTGRLRVLE-EDASSLFASCPYVESVLDSSRYYVIRVESHAFIGIGVSRH---------------NRK------------------ Mellp23 VLWV-ARECLPP-RTSTAGYKAADWGDLWKGRLRIIE-EDLDTLFANCPYVEPVLDSSRYYVIRVEDRAFLGMGFPERSDSFDFNVTLQDWTKPKR--DFSLKDGQTISISLGG Mnele ------------------------------------------------------------------------------------------------------------------ Monbr ---------LPP-RQTNKGYRAADW-GLWTGRLKVTL-TDTTTLFAEAPIVESVIDSSRYFVLKVVNHAFLGMGFADRSEAFDFSVALQDFGKPKH--DLKMAEGQTIKINIKT Morel2 VLLV-IRECVPPLQSSSRGYRAADWGNLWRGRLRIIA-EDGQTLFAVCPYVESVTDSSRYFVVRIEDHAFIGLGFLDRSHAFDFNVALQDHFKPKL--DFSLKEGQTLNLTIAG Mucci2 VLLI-IRECIPP-RTAARGYRAAEWGDLWKGRLRIIS-EDNSTLFAVCPYVEAVLDSSRYFVLKIESHAFIGMGFQERTDAFDFNVTLQDFVKPKK--DYSLKEGQTINITIGN Mydma VLCA-KNEVIPP-RQSSRGYRASDW-KDWTARLRIVL-EDRNSLFAQAPIVEAVSDSSRYFVIKIQDHAFIGMGFTDRGDSFDFNVALQDHFKP---LNLGFKEGQTIKINFGN Neucr2 ILHITSSSVIPP-MRSTKGHMAADWTAIFTGRVRIIE-EDPATLIAAAPYVEATIDSSRFFALRVQDKAMLGVGFEERSESFDFGVALQEAQKEKK--DYSLKEGETITVNLSG Orpsp11 ---------------------AAEW-DLWSGRLRVIS-EDANTLFAQCEYVEPVIDSSRYFVLRIEDHAYIGMGFQERSEAFDFNVALQ------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------ Phybl2 VLLI-IRECIPP-RTTARGYRAAEWGDLWKGRMRIMR-EDPNTVFAVCPYMEPVLDSSRYFVLKIEHHAFIGMGFQERSDAFDFNVALQDFTKPKK--DYSWKEGQTINISIGS Picst3 ------------------------------------------------------------------------------------------------------------------ Plicr1 ILYI-AREIIPP-LKANEGHRAGDWGDLWKGRLRIVE-EDATNLFARAEYVDPVLDSSRYFVVRVEDKAYIGMGFAERTDSFDFNVALQDYTKPKK--DYSLKEGQTFSIAIPG Polpo LLKV-VSEFIPP-RPGAAGYKAQDW-DIWSGRLVIVA-EDNATIFAQCPVVEPVIDSSRYFVIKIKDHAVVGMGFTDRGDAFDFNVTLQDHQNPKK--DYSLKTGQTIHIPFKA Pucgr2 VLWI-ARECLPP-RTSSAGYKAAEWGDLWKGRLRILE-EDADTLFANCPYVEPVLDSSRYYVIRVEDRAFLGMGFPERSDSFDFNVALQDWTKPKR--DFSLKEGQTISISFGG Punst1 ILYI-GREVIPP-LKANEGHRANDWGDLWKGRMRIIE-EDPSTYSSAIEYIEAVLDSSRYFVVRVEDKAYIGMGFADRSDSFDFNVALQDYTKPKK--DYSLKEGQTFSISIPG Rhior3 ------------------------------------------------------------------------MGFQERSDAFDFNVTLQGFVKPKK--DYGLKDGQTINITIGN Rhoto1 ALFI-SRDVIPP-RTSNAGYRAAEWGEMWRGRLRVIE-EDKDSLFAQAPYCEAVLDSSRYFVLTVIDKAYIGMGFPERTESFDFNVALQDWTKPSR--DFSLKAGETISIKLGG Rozal11 ------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------ Salro VQLV-LRQCLPP-RPSTKGYRAADW-GMWTGRVKVTT-QDNATLFAEAPIVEPVVDSSRYFVVRVENHAFLGMGFQERSEAFDFNVALQDFVKSKN--DFSLKDGQTMKIAIKT Schco3 ILYI-AREVIPP-LKVNEGHRAAEWGDLWKGRMRIIE-EDSQTLFARAEYVEAVLDSSRYFVVRVEDKAYIGLGFAERTDSFDFNVALQDYTKPKK--DYSLKEGQTFSISIPG Schpo1 ------------------------------------------------------------------------------------------------------------------ Sorma ILHITNSSVIPP-MRSTKGHMAADWTAIFTGRVRIIE-EDPATLIAAAPYVEATIDSSRFFALRVQDKAMLGIGFEERSEAFDFGVALQEAQKEKK--DYSLKEGETITVNLSG Sphar -------------------------------------------LFAEAKVITPVNDSSRYFALRIENHAYIGFGFADRGDAFDFNAAIQDHFRPKK--DYSMKEGQSIKINFGK Spipu1 VLLV-IRECVPP-RSSTRGYRASDW-DLWTGRLRVIA-EDANTIFAVSPYVEPVLDSSRYFVLRIVDHAFVGMGFPDRSQAFDFNVALQDHVTPKL--DYSWKEGETISIQLGN Sporo1 LLFV-AREVIPP-RQSNAGYRAADWQSMWKGRLRVME-EDKDTLFAQSPYCEAVLDSSRYFVLTVVDKAYIGMGFPERTESFDFNVALQDWSKGSR--DFSLKEGETISIKLGG Stehi1 ILYI-AREIIPP-LSKNEGHRANDWGNLWKGRMRIVE-EDASTLFAKAAYVEAVLDSSRYFVVRVEDKAYIGMGFAERTDSFDFNVALQDYTKPKK--DYSLKEGQTFSISIPG Tapde11 VLFV-CQKIVPP--PTGKGFKTDSWGGIFTGRLRVIQ-EDGQTLFAAAPYVEKAQDSSRYYQIRVVHVAYLGIGFEEREAAFDFQVVLSDFTKPVK--DYSLKEGQVLNIGVKL Thetr TLLV-LEQCVNG-KKTNQGYRAKSW-DLWMGMLKVVAEEDGLTTFAEAPVVEPAIDSSRYFVLRIVDHAFIGIGFQDRNHAFDFNLTLNDHKSPSK--DYSLKEGQTIKVSLRH Treme1 VLHI-AREVVPP-LSTSSGHKAADW-NLWKGRMRVLE-EDANSLFAQVRYVEPVLDSSRYFVLRVEGKATIGMGFLERGDAFDFQVALQSFARPPK--DYSLKEGQTFTIKLPG Trire2 ILFV-ATPVIPP-LTSMRGHSASSWTEIFTARLRVVE-EDPSTLFAAAPYVEPVVDSSRFFAVTVKDKAVLGIGFEERSEAFDLAVSLQEARRT-K--DYSLKEGETITVNLGG Umbra1 VLLV-VRECIPP-RTTARGYRAAEWGDLWKGRLRIIA-EDSASLFAICPYVEPVLDSSRYFVLRIENHAFVGMGFLERSEAFDFNVALQDFVKSKK--DYSLKEGETISINIGK Ustma22 VLFV-ARECVPP-RSSTAGYKAAEWGDLWKGRLRIME-EDADSLFAECPYVEPVLDSSRYFVLRVESKAYIGMGFQDRSDSFDFNVALQDWTKPKK--DLSLKEGETFAIKLPG Walse1 ------------------------------------------------------------------------------------------------------------------ Zygro1 ------------------------------------------------------------------------------------------------------------------ [Cluster2896.fasta_al_trimmed; alignment length = 155] Allma1 RMRDHYDRTLAADLLYLTYNHNVPELSSIVVHNKYVLLNALTQLEAITGEIVRSTSNVKLRDGM-PVGVKVELQGMYQFLDKLVELVLPRLKTWYGIGNIKVGFEPKSMYFPEIEQTFDYP-F-MCGFDVVFKTTANDREARTLLSGFQIPIENA Ashgo11 RVREHYLNTLQDDLLLMNYEHNVPEIESVVINNPFLAIGAAMQLQQITGTSLYAKKDMKVRRGT-HMGAMIELKGMSQFLSTLTEIVLPRIREYKGIGGISFGLTKDDVYFPELAASPDWP-N-TFGMHININTSATDSRARTLLSGFGLPFHGH Aspfu1 RVSQTWESTIAPDILTLCYVHNIPQLERITIHNSSWLHVAGMAVQAISNQTFKSKSSVGIAPGRDTVAVKAELRGMLHFFGKLVDVVLPRIKDWEGVGNITFGLEPENVLFPEIEVNYDYPPKMIPGAHITIHTTATDKDARLLLSAMGIPFYGK Aurde31 RLKEHYHTTLADDLMYMHYTHNNVRLERIVLHNRSLLLGTVAAFRALSGQIVRGRKTV-IRPGV-PCGVKVELKGMYDFLGTFVEFVLPRLRDFAGFGVVSVGLNPAAMLFPQIEVNVDYQ-K-MYGFHINFITNAAQNLARALLSGFQVPFKRA Batde5 RLEEHYYNSLMEDLMVLSYDHRLPIPKRIELKNKNLLLSAIMCLQSISGSPLFAETGDRIRAGM-PLGARVELTGMYGFIDKLTQCVLPRMREFKGIGMMKLVLPETAVYFPDIEPHFDYP-R-MFETDVMMYTTGNDWEAALCLSGFQIPFMEE Botbo1 --------------------------------NKHALITAIAAFRAMSGQIITSTSGVKVRAGL-ELAVKVEIKGMYDFLGTLVDFVLPRMREFPGIGVVAFGLPPTAMLFPQVEINQDYP-R-MHGFHMHFLTNAAQNRARALLSGFQIPFVRR Botci1 RLEQTYKSTISHDIMTMAYVHNIPKIEEVTVHDSAYMHVAGILLQSITGEIHKSTHNVGIRKGM-PVSLTCTMRNALEFLDKCINVVFPKIKDWQGVGNLSFGFNREGTLFPEVQVNYDYPPRLIPGFHVTVKTTASDRHARLLLSAMGVPFYGK Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 RVNEYYQNALQSDLLLHLYEHNVPKLESIVVQSPWLNITTRLQLATITNKILYGKSNIKVRVGR-ACGAKIELFDMSQFISTLTELVLPRIRAFKGIGNISMGLTPEDCFFPELEHFQEFP-N-LNGLQITFKTTATDNHAKTLLSCYGFPFSKN Cangl RVRDFYHSTLQQDMLLINYRHNVPWLENVTINNELMAVSAALQLQQITGKPIYSKTDVKLRKGH-QMGAKVVLTGMSQFLSTLTEIVLPRIREYKGVGGISFGMTSSDVFFPEIDANQDWP-K-TFGMHVNINTTANTAQAVTLLSGLQFPFQK- Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 RLHSHFESTLYPDLMYLTYNHNQPKLQSIVVHNKYVLLNAMTQLEAITGDV-------------------VELDGMLHFVDKLVELVLPRLKNWYGIGNIKLRFEPKVMYFPEIEQTFDYP-F-MCAFDVTFKTSADDWEARVLLSGLQVPVENA Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RLEQTYQSKIASDLLTLTYQHNVPKITKVVVHNSGNLHVAGMVLQAISNVSHKARHNVGLRKGR-YVAVTSTMERADNFLAKLIDVVLPRIKEWKGVGNMSFGLTPDQVLFPEIEVNYDYPPKMIPGCHITIQTDASNKDARLLLQAIGIPFYGK Coere1 ---------------------NAPCLKKVTVHDKNHILSALTALQVITGEIIKAKSDVKLRKGM-PIATKVELKGMFEFLDKLFELVLPRMKEYGGMGNFTMGFDESVILFPEMEMAYDFP-L-VNGFIVNIATSARNASGRLLLSGLGLPF--- Conco1 RLQDYYHNVIQENLMVLKYQNNIPELDYITIQSKHNLLSAFLILETITGTTIYSRSNVKLRSGM-PIGAKVVLKGMYQFLDKLVEVVLPRIKEYKGFGNLAMGFPKSAVLFPDLEIIYDIP-I-VSGFHVQFNTTGRNHDARLLLSGLGLPFNPE Conpu1 RVGDHYHNTLADDLLYMTYTHNVVRLERIVLHNRSSLLGVIEAFRAISGQIVHAKKNV-ARAGI-PTGVVVDIEGMYDFVSTLVEFVLPRLREFNGIGVVSFGLPPDAMLFPQIEVNMDYP-K-MYGMHVQFITNAAQKRAQALLSGFQIPFARK Copci RLEDHYYNTLQDDLMYMTYKHNTVRLERIQIHSKANLLPTLMMLRALTGQLVRGKKSI-LRKGI-PVGAKVDLRGMYDFLGTLVEFVLPRLRDFNGIGVVSFGLPPQAMFFPQLEVNIDYP-E-LPGIHIHFITNAAQDRARALVSGFQVPFVRR Croqu1 RLLEYYDNHLSSDLLYMTYQLHGIRLEKISLDTKKELLGAIYLLQLITGYLSKTKDASRVRRGM-TCGVHVDLRGMFNFVDVLITFVLPRLKDYNGFGTVQLGLPASGMLWPGVEESLEWP-R-KYGMNIHFVTNAATDKARALMSGFRIPFVRP CryneH991 RYSQHYNNSLASDVMYMTYSHTVPKLESIIIHNKNSLLSAIAAFRAISGQVITAKKSAKLREGM-PVAVKVELKGMYDFIQSLVDFVLPRLRDFSGVGVVSFGFGPTAMFFPQIEANTDYP-R-MHGFHVFFKTNLAQEHARTLVSGFRIPFHRR Crypa2 RLKETWQSTIAPDLMTLAYQHNVPEILAVSMSEPTYLLAARSAIQAVMGEIIRINKGVGIAKGN-LAGAKATVYGAYELLDKMIHLVFPRIKEWPGVGNIGWGFTREEFLFPEIQVNYDYPPKMIPGAVVTVQTTASDRHARLLLQAMGVPFYGK Debha1 RLSEHYENTLQLDLLLHYYEHNVPQLVGISINESWLNISTRLQIAQITNKQTYNRSNIKCRVGK-PCGCKAELTGMTQFVSTLTELVLPRIRTFKGIGNITFGLEPEDVYFPEIENFQEFP-N-LFGFHITFKTTATDQQARTLLSSLGLPFYDA Dekbr2 RVLDHYYNTLESDLLLIQYRHNIPRLENITINKPELAIAATLQLQQITGSPVYAKANVKLRPGM-RMGARVSLSGASQFLTTLTEIVLPRIREFRGIGNIAFGLRPEDIVFPEIENNQDWP-K-TFGMDITLHTSATDADARILLSGLGFPFTGG Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------MKHLSYN-----LKKIVLNKKMNIISLYQVYSLLN-KFNKAKGSIKLRKGS-VVGVYITLSSINNFLVKLIQLKTPNI-DLNPIGNVSRGF--KNIESPEFTELYDVN-Y-NIGYNVNFVFTKSLAENVFKLSSLKLPLRD- Fomme1 RLHDHYQQTLRDDLMYMTYIHNVVKLEKICLHSRSNLLGTIMAFRAISGQLVRGKKNV-VRPGL-PIGVKVEIKGMYEFLGTLVQFVLPRLREFEGVGVVSMGLPPDAMFFPQIEVNQDYP-R-MYGMHIHFVTNAAQNKARALLSGFQLPFARR Fusgr1 RLRHTYETTVAPDLITMTYQHNVPEIEAITINNKEYLHVCRAVIQAISGEVTRVKNGVSVRKGD-KTGCKVTLKGAYEFLDKLITLVLPKIKDWPGIGNLAFGLQPAWMYFPEIEFNYDYPARLMPGCDIFIKTTGSDRQGRLLLEALGLPFFGK Galma1 RLEDHYHTTVKDDLMYMTYTHNVVRLERIQLHNKGNLLPAIMQLKALSGQIVRGKKSV-VRPGI-PVGVKVDLKGMYDFLGTLTEFVLPRLRDFNGVGVVSFGLPANAIFFPQIEVNVDYP-R-LYGMHIHFVTNAAQDRARALVSGFQVPFVRR Ganpr1 RYHSHYMSVLAQDMLYLTYQHKLPELDSITVRNKHLILLAMMQLRCISGEPTFATWSDRLRKGQ-AVGAEVFLKGMYSFLERCVECVLPRLREWEGWGSVTVTLPSQAVLFPDIEPYFDFP-R-LYDIQIQFRTSATPEEAVLLLSGFQIPFKDP Gloin1 ---------------------TIPRLDEIYIHNKQHLLSGLMALQCITSNVVYSKTGVKLRAGM-PIGCVVNIKGMYTFVDKLVEIVLPRLKEWYGVGNIAMGFPSSALLFPEVEGNYDFP-L-MTGFDVIFNTTATDHEARALLSGFQIPFNEK Hisca1 RVEQTYESTISHDILTLCYVHNIPKLDKITLHGSGPLHVAGMAIQAISNQTHKMKGNVGVVPGKAYIAVTAELKGMYHFFGKLVDVVMPRIKDWKGVGNISFGLDPDMVLFPEIEVNYDYPPAMIPGCHITIHTTATDKDARLLLNAMGIPFYGK Klula1 RVREHYYNTLQSDLLLINYSHNIPDIESVVINNQYLPISAALQLQQITGKALFSRNDVKVRRGT-QMGAVITLKGMSQFLSTLTEIVLPRIREYKGIGGLSFGMTSDEVFFPEIDANQDWP-V-TFGMHININTTATDVQARTLVSGFGFPFNGS Lacbi2 --------------MYMTYKHNVVRLEKIQIHNKGNLLGAIMMMRALTGQIVRGKKSV-LRPGV-PLGVKVDLRGMYDFLGTLVEFVLPRLRDFNGIGVVSFGLPANAMFFPQIEVNVDYP-K-LAGMHIHFVTNAAQDKARALVSGFQIPFIRR Lenti61 RLANHYYSTLQDDLMYMTYVHNVIQLERIQIHSRTNLLGPIMALRAISGQIVKGRKNL-VRPGL-PVGVKVDLKGMYDFLSVLVEFVLPRLRDFQGIGVVSFGLPPTALLFPQIEVNFDYP-S-TFGMHIHFITSAAQNRARALLSGFQIPFARS Malgl1 RLREHYERTLAADMMYMMYEPDIPRLERIVFTNKQALLPLLGQMRAITGQVLRARQGAKLRVGM-PVGVKAVMYGAYEFIESLTTFVLPRLRGFAGLGVVSFGMGPEAMLFPQVEINMDYPGR-RYGFQVDCVTNQATERARTLLSGLGLPFVRR Mellp23 RLSEYYDHHLSSDMLYMTYQLHSIRLQKISIDTKKELLGAIYLLQMITGQLSQTKDASRVRRGM-TCGVHVNLKGMWNFIDVLVTFVLPRLKDYNGFGTVQLGLPSSGMLWPGIEESLEWP-R-KYGMNLHFVTNAASDKARALMSGFRIPFVRP Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ELVKNRNRLLTNDLII-----QFKHIKSIEIISKLRIFTTYFMLSRIFTTFIKAKKSVNVREGM-EVGVKLNLRDMERWLKKWLVLLIFAIQPYNGFNKMESNINDNNLFYPNFSSNYQIP-L-NTGLHIRVKFNHNKDYKNFILSYYLIPSF-- Morel2 RLREHYRNTVQDDLMVLTYNHHIPELVKIDVHSKYNLLSGFMAIQSITGEIINSKKGVKLRAGN-PIGCKVTLKGMYQFLDKLVEVVLPRMKEWPGLGNIGMGFAPSALLFPEIENNFDFP-R-MTGFDVTFTTTATNLEARLLLSGFNMPFQVK Mucci2 --------------------------------SKSHLLSAFMAFQSITGDVVYARNSVKLREGM-PVGVKVTLRGMYQFMDKLVEIVLPRLKEWPGLGNIALGFPPSALLFPEIEGSFDYP-K-MTGFDVIFNTTATNTDGRLLLSAFSVPFKSN Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RLKETFRTVMASDLMTLAYIHNIPEIKEITVSNPDLLIVARAVLLAMTGEMTRSKNNVQLQANK-PAGCKTTIYGAWEFMDRLIHLVLPRIKDWKGVGNVQFGLNPEDVLFPEVECNYDYPAKMIPGCHIAIKTTASDRQAKLLLQSLGVPFYSN Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RAEQTFDSTVSPDIMTLCYVHNIPEIERITIHNSSWLHVAGIAVQAISNETFKSKSNVGIAAGRDSVAVKAELYGMYHFFGKLVDVVLPRIKDWEGVGNITFGLIPENVLFPELEINYDYPPKMIPGCHVTLHTTATDKDARLLLSAMGIPFYGK Phybl2 ---------------------TIPKLDKITLHNKSNLLSAFMAFQSITAEVVYARNSVKLREGM-PIGVKVTLRGMYQFMDKLVEIVLPRLKEWPGMGNVAIGFPPSALLFPEIEGSFDYP-R-MTGFDVTFNTTATNTDGRLLLSGLSVPF--- Picst3 RVAEHYENVIKSDLLLHNYQHNVPEVSLIIIQESWLNISTRLQLSQITNKQIYAKANIRLRRGK-PCGGKVELTGMSQFISTLTELVLPRIRTFQGIGNITFGLDPEDVGFPEIENFQEFP-N-LTGMHITFKTNATDDRARTLLSSLGFPFYNP Plicr1 RLADHYHHTLQDDLMYMTYKHNVVKLEKVSLHNRSNLLGAIMAFRALSGQITRGKKTV-IRPGI-PCGVKVDMKGMYDFLGTLTEFVLPRLREFSGVGVVSFGLPPIAMLFPQIEVNMDYP-K-MYGMHIHIITSTAQNHARALASGLQIPFSRQ Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RLAEHYHNQMASDLLYMTYELNLVRLKKISIDTKKELLGAIYLLQLISGQISRTKDKSKVRTGM-VCGAHLEIRGMFDFLDILSTFVLPRLKDFNGFGVVQIGLPDHAMLWPAVEESLEWP-R-KYGMNIHFLTNAASDKARALISGFRVPFVRP Punst1 RLLDHYHTTLADDLMYMTYTHNVVRLEKIVIHNRQQLLGAVMALRAITGEIIRGKKSS-KGKNA-PLACKVELTGMYDFLETLAEFVFPRLREFNGIGVVEFGLEPDAMLFPAIEVNVEYP-R-LYGMNIHCITNAAQNKARALISGFQIPF--- Rhior3 RLKEYYESTIAEDLMVLGYDHVVPKIDKITLHNKSNLLSAFMAFQSITGDVIYAKKSVKLREGM-PVGVKVTLKGMYQFMDKLVEIVLPRLKEWPGLGNVALGFPPSALLFPEIEGSFDYP-K-MTGFDVTFNTTATNTDGRLLLSAFSVPFNVK Rhoto1 RLEDHYTHSLSHDLMYLLYSHSVPRLESIVVEAKSTLLPLIMAFQAITGVVTRTTKKSKVRAGM-PSGVKVELRGMYQFLETLTDFVLPRLKTFAGIGVVAFGLTPDAMLFPQIEVNLDYP-R-LFGMNIFCRTTAAQDQARALLSGMGLPFVKR Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 RLNDHYLNTLQSDLLLINYSHNIPGLESVVINNQLLAITAALQLQQITGHPIFSKNDVKLRKGH-QMGAKVELKGMSQFLSTLTEIVLPRIREYKGIGGISFGLTAEDIFFPEIDANQDWP-K-TFGMHININTSALDYQARTLLSGFQFPFFGE Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 RMLDHYHTTLQEDLMYMSYFHNVVRLEKISLQNRSNLLGPIMALRALSGQVIRGKKSV-IRKGI-PCGARVDIRGMYSFLSTLTEFVLPRMREFGGIGSVSFGLPPEAFYFPQIEVNQDYP-K-SYGMHIHFVTNAAQNLARALMSGLQIPFSRR Schpo1 RLQEHLHDTILPDVLAASYRHNLPSISKVVVSDKTQLLSTMMAFRSITGEIVYARKDVKLRSGV-PVGVKVTLTGMYTFLSILSELVLPQLHDFKGLGNISFGLPSEVMLFPQIEAVYEYP-HSLPGFNVNITTNSDTRLARFFVSSL-IPFTDG Sorma RLKETFRTVMASDLMTLTYIHNIPEIQEITVSNPDMLIAARAVLLAMTGEMTRSKSNVHLQANK-PAGCKTTIYGAWEFLDRLVHLVFPRIKDWKGIGNVQFGLNPEDVLFPEVECNYDYPPKMIPGCHIAIKTTASDRQAKLLLQSLGMPFYNS Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 RLEEHYYNSLLEDLMVLTYDHRLPIVSKVMLRNKTILLSAIMSLQSITGEPLFATVGDKIREGM-PLGARVELTGMYEFLDKMTQCVLPRLREWDGLGSITLSLPSTAIYFPDIEPHFDYP-R-LFDTDIVIQTTGSDWETVLCLSGFQVPFLKE Sporo1 -----------------------------------------MAFEAVTGVITRSTKKSKIRAGA-PTGVKVELRGMYTFLESLVEFVLPRLKTFQGIGVVSFGLPPEAMLFPQVEINLDYP-K-TFGMNVFCITSAAQDQARALLSGVGLPFVKR Stehi1 ----------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 ---------------------NVPKITTVYIHDRQKLLSAFMALQTISGELILSRKSVKLRSGV-PVAVKVKLQGMNQFLSTLFEIILPSLKDFTGIGNLAFGLPGAAMRFPEIEANYEYP-I-LPGFHVLINTTANDREARQLLTGYGLPFKKA Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 RYHQHYDSTLSTDLMYMSYDPTIPKLESIVLHRKQNLLSAIQALRVISGQIVNSRIGAKLRAGM-PIAAKVEIKGMYDFIQSLVDFVLPRIRDWPGVGIVSFGLPANAMLFPQIESNIDYP-R-LHGFHMYFKTNAAQEQARALLSGFRIPFYRK Trire2 RLKHTYDSTIAPDLMTLTYKHNIPEIEAVTINNKEYLHVARAVVQAISGEVTTVKHNVGVRKGS-KAGAKTTLRGAYDFVDKLVTLVLPKIKDWPGIGNIAFGMQPAWMYFPEIEFNYDYPPKLMPGCDIFIHTSASDRQGRLLMEALGFPFYGK Umbra1 RLKEHYHNIVAEDLMVLTYDHNIPTLDKITVHQKNHILSAFMALQSITAEVIFAKTSVKLREGM-PIGVKVTLRGMYQFLDKLVEIVLPRLKEWHGLGNIGIGFPPSALLFPEIEGSFDYP-K-MTGFDVVFNTTATNAEGRLLLSGFNVPFKGA Ustma22 RYQEHYRTTLASDLLYMTYDPEIPKLDRIILTNKHALVPLIAQMRAITG------QG-RDHSSM-PVGVKAILPAAHEFLEVLTTFVLPRLRSFAGFGVVSLGMHPEAILFPQIEINLDYPNK-PLGFQIDCITNQATEKARALLSGLGIPFVRR Walse1 RLKSHYENTLAPALLYMNYNANI-KLEKVIIHNKGALLSAIMALQSISGTVCKARKGVKIRQGM-PLSVKVELTGMYDFVDALTEFVLPRMRDFSGVGVFQMGLPPAAMLFPQIEAAFDYP-R-SHGMDIKFITNYAEAKTRALMSGLRIPFVPK Zygro1 RVHEHYLNTLKSDMLLINYAHNIPEVTSVVLNNKLLAISAALQLQQITGHPIFSKSDVKLRRGN-QMGAKIELKGMSQFLSTLTEIVMPRIREYKGIGSLSFGLTSEDVFFPEIDSNQDWP-K-TFGMHININTSATDVQARTLVSGFQIPFHGV [Cluster2904.fasta_al_trimmed; alignment length = 216] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ADEFAEVLKKLVEIISAYNLLVHLVYLAKPIAISILTTIFNTLAPTDSSRFHVLLAIVAVIRQLPTWLS-AWLDDEDAQKLHLAIADAAQASAVRALFTSLTAAD-AIQ-ALEIF-TADTLDAYTKMRLLTLASLAASRSLPYTTIASALRVPEDVEKWVIDTIRAGLVEGKLSQLRSEFLVHRATRVFGEKQWAEVQGRLMVWRRSLESVLGVLR Aurde31 VKELVKVIELVVEIEGFFNLLIAQIAILAVVKFRILTNLFNALARTSPLRVNVAEALIALAADVEKWLA-EWLPLERKCDFLKTVADAVAKATLETIFDSLAKID-AVQ-SAKIF-MLESVKEYHKIRLLTLASLAAQRDLPYGEIAVALQVESKVEIWVIDAIRAGLLSGKLSQPTQTLRVTRSTRSFARGEWETLEKRLATWKSGLLGVLEVVG Batde5 --------------------------------------MYNSLESTSYGRFKTYKTIVQVASALEDWIS-EWLTLVDRRALYLLLSVELGKSLVQAIFEDVLSLT-AVQ-ALKIF-LDQSLTKYRKMRILSLATLATEGEVSYSTISKALDVSDDVEFWVIDAIRAGLVDAKINQLKQTILVSRATRVFGVPQWKLLQSRMLLWKNNLGECLQVIE Botbo1 IQELVKVIMKVLEVEGFFNLLDAHITLIRVLKYRVLSNLFNALPRSSPLRVEVYTALLNLANEVDRWLS-EWISQDEKSAFLKKIADAYNKSALDVIFNDLLKIE-GVQ-AVKIC-LSGGLADLRKIRYLALASQATKRDMPYSEIASVLQVDKEVEAWVIDTIRAGLLSGKLHQPAQTFHVIRSTRSFGREEWKTLEKRLLAWKTGLLGVLEVVE Botci1 AQELAEALKKLVEFTAAYNLLVYLCNLAKPIALNVLTTIFNLLQPDNETRFNVFQAVLKLIK------------------------------AIKALFHDLTSLP-AVQ-ALEIF-AEKELEDYRKMRLLTLASLAASRELEYKRISKALQVAEDVEMWVIDVIRAGLVEGKLSQQKQVFLIHRTTRVFGEKQWREVATRLDQWKESLRGVKEVIS Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow LADVAEALKQVIDIEAPFNSLLFLAALLAAVRLRVLSVVFNTLDANSLNRFETFKALVSFAGALADWIG-QWLTGTQTRALYRLIYDVLTQNAEKCILDSLLQLA-AVK-QLLIF-VRDNFQAYVKMRILTLVTLASTSEVEFSRIAETLSVPEEVEAWVIEAITAKLIEAKIDQLNGKIVIGRATRIFGKPQWQQLHDRLSSWQNNLNDILVVIK Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ISELQNDVKQLIDIEGVVNSILSLLLLCEQLSLNLLHNLFHGYPTKTPFLCKVYSTWLKLAKVLSSWLE-DWAGEEGRQNVLRLLYEAQLNCAIRCIFNQLLTLK-PVT-FLNIF-VSGNIKEYRKMQLLTLVDNFGSREISFDDIIARLDISDDVEEFIIDAIQSKLMRGRIDHVNRKVIVSQACRIFGRAQWESLASRLEQWRDNINRVNGKLQ CocheC53 TDEFAEVLKKLVEFIAAYNLLIHLVNLSAPIALSILSTIFNTTQPTSEARYQVLLAILRVIRALDTWLL-EWTPDDDARKLYLAVSDVAADASLRALFQDLTDLD-SIQ-ALEIF-NSDLLDDFRKMRLLTLASMAASRSLPYDKIAKGLQVPEDVEMWVIDVIRAGLVEGKLSQLNQTFLIHRSTRVFGDNQWREVASRLDLWRNSLQGVLHVIQ Coere1 VEELAGV-----RIESAYNQLFAIA--KDIAGLRVLNSLYN--VTKSGARAAVFGGLAELAGRISAMVN-EWVKARKQGLVSLLALR--KAFDIEQIVDALAGLP-TVQ-TLGLL-ENMLGSDYDKMRLLTLASLAAEQPIEYTEIAKAIDVEDDVELWVIDVVRSGLVQGKMHQGSRTLVPSRSTRHFGTPQWQHLAQRLDEWRVALDSLLPVVR Conco1 VVELSVVFDKLVQFEGSFNLLLSCFKFTQLLKLKVLENLYNSVEPKTELRYVVLKAILQVVKKLKTWIK-NWVDTDKARNMYINIYDTLKSGGQVALFEDLFLTA-PVQ-ALKIF-LDQDLAQYHKLRLLTLTNLGTEVPIPYSEIAAKLQIESEVEMWVIDVIRYGLIEAKINQHDETVTISRATRSFTKDNWENLDQALTNWKDSLHQVIQILK Conpu1 VQELLKAVTFVIEIEGFFNLLIAHVRILDIVKYRIMSNTFNHSPHSFAIRPLIYTELLKTATAVDRWLV-DWISDEEKSAFVKQLVDAYQTSAVSAIFDPLFKLD-AVV-AAQIF-LSGGLQEYHKIRLLTFSSLGFQKELPYSEIASHLQIDSEVEKWSIDVIRVRLLTGKLSQTTKTLRVHRATRTFEREQWEALEKRLLAWKAGLASVISTVA Copci ILELVAVLKDVLEVEGFFNLLYAHLNLLQSIKYRVLSNLFNSLPRNSPLRSLVYTTILQIAVEVQKWIS-EWLSDEQKAEFLKQVADAFAKTAVTALFDPLFKLD-AVI-AVQVF-INNGLAEFHKIRLLTLASLAVQQHLPYAKIAEGLEVDSEVEKWVIDVIRAGLVWGKLSQNTQNLHVTRATRSFEKEQWATLEKRLQAWKSGLTGVLEVVS Croqu1 VFEAAKIVLEVWQLEATANLLITLLQLLEAVRFTALFTLFNALPAPTAFQLVVLSKLTDMGSTVPSYLT-QWVSSPNGVKLLAKVIRVLQQGVEQAIWDVLDNIR-PIAHYVGLL-KSPTTK-YRKARLLTLTELCAGGEVTYAEVQTTLGLEMEVEEWVINAVKAKLISARLHQPSQVIYVTKSTRSFGLNHWQMLQSKLKTWGGSIDHLIGIVG CryneH991 ITELAQVVKSIVEVESSHFLLQHVLDVNEAVASRVLKNTYNFLSSNSPIRPSTLLSLMSLLASLLPALS-SWIPSSEKVSFLTTASGLYQSTVEKAVLDDVLAVQ-GVKEQLELF-EGDEVEAIRKLRLIALVALCAKRQLEYAPIAKALTIESEVETWVIDAVRSKLIVARISQPQSLIRIQSISRRFGPNEWQLLEKRLEQWKKSVNEARQVVE Crypa2 LQEIADALAAIVEIGPAYNLLIFAVNLTKPIALGSLSTVFNLLSKDDPVRFNVFLQIVRFVKMVPGWLE-AWTEEEGRQRLYVEIADAAEAASLRALFQGLRALA-PVQ-SLDIF-AEQDLEDFTKMRLLTFASLAASREIPYDVIAKGLQVPEEVELWIIDVIRAQLVEGRMSQRDRVFKVHKTIRVFSDKQWRELQSRIDVWKTTIGHVHTVLR Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi YNDLIEFLSKIVDIEGFFNVILTILKIRDSLKIKILTNLFNSFQPKSTQRYDIFFALVKLASDIDSWLE-DWVSIQQKRKLYKLISNIFKEKCIESISDYLLDLP-AVQ-YLKIF-ATEQLDSFQKIRLLSLATLTSESKVPYSLISKMLQIDNEVEMWVINAMEGDLLDAKLDQLNRIVNVNSSTRVFNKSQWSQLGQRFSVWKSSVKNLLQVIE Dmel VQELRDDLHKIIQIDGILNSIVSIMAYCEKMCLQSLWRLFNNLDTASPLRYHVYYHLVQVAKQLKSQFA-NCPSSEQMQKLYRLLHDVTKDTAMKCILDPLLSLK-PVR-FLSIF-VSEKLPAYKKMRLLTFMQLAESPEMTFETLTKELQINDEVEPFVIEVLKTKLVRARLDQANQKVHISSTMRTFGAPQWEQLRDLLQAWKENLSTVREGLT Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba APEKRKLLNFFIDIEGAFNIILAIALFATKTIFKILANLFNALPTDSVLRYKVFRVLLTTAIQLPKWFA-EWSSNADIRSVYKQLSDALFASLISLLIDVIIDLP-VIA-LLKIF-FKGDSAEFEKIRLIDLSTLALKTPLSYEAIASHIGFSDDVEHWIIEAVRKNIIVAKIDQISRSIVVSGSR------------------------------ Fomme1 VQELVNVISQVVEIEGFFNLLFSYLRILDVIKYRILANLFNAIPRTSPVRLVVCKTLLRLAVEVDRWLN-EWASAEEKCEFLKNVADAFASASLQLIFDPVLKLE-SVQ-TLNIF-NKGSLGEFKKLRLLVLSELGFAQNIPYSEIASSLQVESEVEKWAIDVIRSGLLSGKLAQTTQTLHVVRASRGFAIEQWAELEKRLLTWKEGLAGIQNVLS Fusgr1 AAEMAEVLSKLVEYTAASNLMTHLVTFAKPLSLNALTTVFNLLEPSNPVRARVFMEILKFLRSLPEWLT-TWTDADFQRKIYEEVAEVALEASLRAVFQDLRGIP-SVQ-ALDIF-AEQDLEDYRKMRLLTFSSLAASREIEYSKITKALQIPDEIEMWAIDVIRAGLVEGKLSQQRQKFLVHKVTRVFGQKQYQELANRVDHWRTTLQNVLGVLR Galma1 ILELLLILSKLLEIEGFFNLLFAHISLLKTIKYRVVSNLFNTIPRTSPLRLAVYQTLLQIATSIEKWLS-EWISDEEKSTFLKSIVDAYVQAALDAIFDPLFKLD-AVV-GVQIF-LNSGLPEFHKIRLLTLASLAFQQNLPYSKIAEALQVESEVEKWVIDVIRAGLVWGKLSQTTQSLHISRATRSFEHEQWQALEKRLVAWKTGLAGILDVVA Ganpr1 --------------------------------------LYNSLLPNSPFRFDVTVRLVEVAARIDSLVQ-EWMSLEQTRQLYVLLSDTFKEKVAMAVFEEVHALP-AVR-AIQVF-LDGDLAAYRKMRILTLITVTGRGKVDYKTIAKALEINSEVEVWVIDAIRLNLLDAKMDQLTKSVQVRRTTREFKLQQWKALSLHLEIWRKNLGDVATVLQ Gloin1 ASEFAQVFQLFAEFEAIFNLLIAILSSIESLKLKVLQNLYNTLEYASPLRYDVFLTILDIAAKLDTWVK-EWISTNQIRELYMTVSNRLKEAVIRAVFEDILELHVAIQ-CLKVF-LNGNLKEYRKIRLLTLASLASEREISYETIAKALEIESEVEMWTIDVIRANLIEAKINQVKKTILVNRSTRTFTMEQWKQLSAKLEGWKKSLVDILQVIA Hisca1 ADELAEVLKKIVEITAAYNLLIHLIYLAKPFAISILSTIFNTLAPQDTGRYHVFLAILAVIRQLPIWIG-SWLDEEDLQRLHLAISDAAKEAALRALFTPLTASD-AIQ-SLEVF-AADTLDVYTKMRLLTLASLSASRSLPYDTIANALRIPADVEKWVIDTIRAGLVEGKLSQLKGEFLVHRATRVFGEKQWAEIQGRLMVWRRSLENVLGVVR Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 ILELSLIFSKVFEVEGFFNLLYAHLTLLQTLKYRILANLFNSIPRNSPLRLAVYNTLLALATSVEKWLS-EWISQDEKSTFLKSIVDAYAKAVINAIFDPLFKLD-AVV-NAQIF-LNDGLVEFRKIRLLTLASLGCQNNLPYSKIAESLQVDSEVEKWVIDVIRAGLVWGKLSQTAQSLHISRATRTFERKQWEVLEKRLVAWKSGLAGILEVVS Lenti61 ILELVKVLASVIEIEGFFNLLFSHFSLLSTIKYRILSNLFNAIPRQSGLRLPVYKTLLELASAVDKWLS-EWVSSEEKSAFLKLLVDAFQKAAVDAIFDSLFRLD-AVV-AAQIF-LNDSLAQYRKIRLLTLATLGFQRDIPYSVIASALQIESQVESWVIDVIRAGLLTGKLSQTAQTLHVTRATRAFEHEQWELLEKRLHEWKAGLASVLETVS Malgl1 ADECCEVVAKLTELEGLYNLVMALLHLVNVVKYRILSNIFNLLPTASPLRLRVFKALLTLVSMVPIWLA-QWISSEEKHECLCHVADALQLPAENAIMEEVLRVA-DTL-NLRLI-VSGTRADFHKMRLLDLASLCARSEVSYQDMAQTLGVSDEVEAWVIDVIRAGLVSGKLSQVKRSFRVYRSTRTFEKSQWESLEQRLSQWQHSIQTLLRTMQ Mellp23 VFEASKIVEEIWELEATINLLITLLQLLEAIRYNVLFTLFNALPAPI-LQLNVLQKLSEMSQTVPSYLT-SWMKSNEGIRLIQNIISLLTSSIEQTIWDLLDEIK-PISNYIQLL-KSNETKNHFKSKLLTLTDLCSKGKVSYEEIQSALGLKMEVEEWIINAVKAKLISARVDQPNRLVYINQSSRSFGNQDWKGLGTKLGQWTDSIDQLIEVVD Mnele VLNLVDTFLELLEVESAFFSLISMIKLSNAIKSKLLSQQFNCYQPSLSSTYVLLVNVLKLVVEISDWMT-KWSDVQEQRVIYRLLHEAFSAVVISHIMDHLLDLH-PIR-ALQIF-VNGDLNDYRKMRLLTLASMAQDSEIEFSQLVEKLNLAEELEPFVIEAIGSGLIKGKINEPEGKISISSTIRTFKEPQWLFIMNKLEMWQK---NLVIIQE Monbr VLELLSALPKLLGMEGVCNSCIRLCNLADIIRLRALKNVFNRIDSNDQQRCHVFKNIVALACSLPRWLK-EWSDGELERSTYVHVATCLDKAVERTILYALSRLP-VVQ-NLEAF-VSGDYEAYRRVRLMVLANKCADSEVSLADIAEAIHIEAEAEDWVIEVVRAGLMDAKIDEMAGTVVITRAKTKFDAEDWKQLRDQLQMWHENIARVSSMLG Morel2 VAELAEATNILVEFESAYNLLVAIAQILAGLKFKVLSNIFNTLPANSPLRLSVFTAIVDLAVAVPSWIS-EWVDAQAERALLLTLSDRLKESIVESIFENLLKIE-AIQ-NLSVF-MSGNVQDYRKIRLLSLASLGSERELSYQEIAKALEVESDVELWVIDVIRAGLVEAKLNQVSKLVIISRSIRTFGNAQWQQLSQRLNGWKQSLADILQVIA Mucci2 ITDLATVYAELAEVEGAFNLLIVTVALVDTLKQKILLNLYNALPGNSPLRYNAFVGLVEATAQIDAWTK-QWIDQQTQRNLYDYLSQVLLKAVLRAVFEDLLQYN-AIQ-KLDVF-LNGTLSTYHKMRLLSLASLGSERELTYAEIANNLQIPDEVEMWVIDVIRAGLVEAKLDQLNKTVIVHRSIRVFGKEQWKKLSTSLSAWKDNLNEILAVVA Mydma AKEIRDELSSLLDLEAMMNSFISLIKFILKLRIKLLNNFFIGLPDNNPLRYDVYIGQLQLSIKVKEWLG-VWVELEEKRTCYRLLHASLKHEAVECIMDHLLQLK-PVS-ALTIF-VSGQLTDYEKMKILTMISLANQKEITYQKIIQTLGLTDNLEEFVIELVKSGLVHAKIDQINERIIIRSVGRTFGKNEWESLQQKLQTWVTNLNVIKTNLE Neucr2 AQEMADALDLIVDFTPAYNLLIHLVNLLKPIASNALTTIFNLLDKSNPLRFNVFMQIVRFIRQVEGWLQ-EWSDSESQRKLYVEVSDAANDGSLRALFNDLRSLP-SVH-ALDIF-TEQDLEDYRKMRLLTFASLAASREIPYASIAKALQIPEDVEMWTIDVIRSKLVEGRLSQKQKVFLVHRTTRVFGEKQWRELGTRVDQFKTVVDRLVGVVR Orpsp11 ALKLVDAFSKIIDLESIFNLEIAICRLANIIKMKILNNIYSNLEVNDPLRYDVYLSIIKFSAKLDLWLK-NWSSVEQKRELFLTLRNLLNESAREAIFEELLKLR-AIQ-NLKIF-LAGDINDYKKIRMLTLVTVVGQGRVSYSVVQEALNIPEEVELWILD------------------------------------------------------ Pench1 ADEFAEVLKKLVEITSAYNLLVHLVYLAKPIAISILTTIFNTLSSNDSSRYHVLLAVVAVIRQLPTWLS-AWLESDDTRKLHIAIAEAATAAAVRALFTPLTASD-AVQ-ALEIF-TSDTLDAYTKMRLLTLASLASSRSLPYDTIASALRVPSDVEMWVIDTIRAGLVEGRLSQLKSEFLVHRATRVFGEKQWSEVQGRLMVWRRSLVNVLSVIR Phybl2 ILDLAEVYTKLAEVEGAFNLLVVITALVDTLKQKILLNLYNALPVTSALRYNAFVGLVDVTAQIDRWVK-QWIDIETERNLYSNLSDKLRQAVTRAVFEDLLQYS-AIQ-KINVF-LNGNLSTYRKMRLLSLASLGSDRELTYAEVAKALDISDEVEMWVIDVIRAGLVEAKLDQLNKNVIVHRSIRVFGKEQWQQLGARLNTWKDSLNEILAIIS Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 VQELVKLFTMVLEIEGFFNLLYSHLTLLTTIKYRIHSNLFNALPRRSPLRLTVYNALLSIASTVEKWLG-EWISPAEKSEFLKTIYIAFEKAAVEAIFDQLFKLD-AVI-AAQLF-LNDGLTEFHKIRLLTLASLGFQRDLPYTQVAAALDVESEVEKWAIDVIRAGLVTGKLSQTTQTLHITRSTRTFERAQWEALEKRLVAWKSGLAGVLEVVV Polpo YIDLIEFLSKLIEIESFFNIILTVLKIRDVLKIKLLTNLFNSFSPKSPMRYEVFYVLVKLASELDTWLD-DWASIPQKRKIYKLISTIFKEKCIESISDYLLDLV-AIG-YLKIF-ATEQLDSFQKIRLLSLATLTSEASVSYASISKSLQIDDKVEMWVIDAIASDLIDAKLDQLNRVVHVNSSTRVFNKAQWTQLGLRIDAWRSSVKNLLQVID Pucgr2 VFEASKIVEELWELEAATNLLLTLMQLLEAIRYTALFTLFNALPAPTALQLTILSRLADMAASLPSYLT-QWLGSPVGVATIEKVIRLCEQGSAQAVWDLLEDIV-PISQYLSLL-KSPSTK-FRKARLLTLTDLCGNGEVKYSEVKECLGLAMEVEEWVINAIKANLIAARLHQPSHVIYVTKASRSFGTPQWANLETKLKGWGNSIEHLIRVVE Punst1 IQELVTVFQKVLEMEGFFNLLFAHLTLLHVIKYRVLSNLFNALPRRSALRLPVYNAILRVASIIERWLS-EWISTEEKSEFWKGLADTYVN-AIDAIFDPLFKID-AVL-AAHIF-LNDGFPEFRKVRLLTLASLCFQKDISYSTIASALQIESEVERWVIDVIRAQLLTGKLSQTSQTLRVIRAKRTFERAQWEVLESRLVAWKQGLSSVLQVVS Rhior3 IIDLATVVTELAEVEGAFNLLLVIITLVDTLKQKILLNLYNALPGNSPLRYQAFVGLVEATRQIDAWAA-QWIDQNTQRELYNYLFEVLSKAILRAVFEDLLQYK-PIQ-NLDVF-LNGTLSSYCKMRLLSLASLGSERELTYGDIASSLQIPEEVEMWVIDVIRAGLVEAKLDQLNKTVIVHRSIRVFGQEQWKKLSTALSTWKENLNEILAVVG Rhoto1 --QATQVVAELVEFEGFANLVLSLVQLASALRYTSLATVFNSLPASATLRLALFRSLVAFTAKFVSWLLDEWVESDLADEAVLEVVDTLVSKAAKLVFASLVPSTYP---SLKTF-QSPSSSS-TKLRLIKLAHVCADQSVSYDEIAKAVGVEEEVETFVIDAIRASLLQGRLSQPTQTLYITRVSSSFTAEQWKTVQARLEDWKGAVERIRGSVE Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro LRALAEVLSRIVEEDMLDDMLLNAMPFLTSLVVSTVTSLFNLLPANSKHRYDVLYQLLSCGLEVDAWIK-DWLTQPQQRALFKLFAAKLQEAIAQAL---LLGMD-AVK-HLEVL-TKGDVPGFTRVQLMALAKFCAKTQVTFAEVASGLSIQDQVEQLVINALRHSVLEATIDDVNKVVNVTRVIDSFEPEDWKSLHAQLMAWKTNIEQVRTTLD Schco3 IQELVEIFSHLVEIEGFFNLLFSHLPLIQTIKYRILTNLFNLLPRTSSLRLDVYNALLAIAAAVEKWIS-EWVTSEKKSQFLKAIVDAFVQAAAQAIFDPLFKLD-AVV-AAQIF-LSGGLPEYHKIRLLTLASLGFKQNLPYSTIAEALDVDTEVEKWVIDVIRAGLVLGKLSQTTKTLHIVRATRAFEREQWEALEKRLVAWKTGLVGVMEVIA Schpo1 VEELAEVLNLFLELEPIL-AVFINLALEQIAILSVLSILFNTAVKERQARLSILTSVVTLTTRFPDWLK-EAVSVSDHRAFNIFVSKAIQSYVRELVFDDIVTLP-PVQ-QLGIL-SGGMTDDYRKMKLLTIASLATQNTLSYGDVAKSLKIDNEVELWIIDVIRAGLVEGRMSQLTKTLSIHRSSRVFGKHEWVALHEKLAKWGSSLRYMLQVME Sorma AQEMADALDVIVDFTPAYNLLIHLVNLLKPIASNALTTIFNLLDKSNPLRFNVFMQIVRFIRQVEGWLQ-EWSDSDSQRKLYVEVSDAANDGSLRALFNDLRSLP-SVQ-ALDIF-TEQDLEDYRKMRLLTFASLAASREIPYASIAKALQIPADVEMWTIDVIRSKLVEGRLSQKQKVFLVHRTTRVFGEKQWRELGTRVDQFKTVVDRLVGVVR Sphar ARELAALCAALIAAEASIYAIVNLCRLVSVVRVKLLAFLFNNMNADSSARYTCYNSLVKVCGALPEWLA-EWCDQSQTRTLYRNIFEACKKCACEYLFDEAVELE-AVK-ALQVF-FSGDYKAFKKMKLLTLISLSTDNEVEYKQVAESLQVEDLVELWLIEAMRKELVTGKLDQLNEKVIVRRAVRTFGRDNWEVLSERLEAWSTAMAECLETLR Spipu1 ALELAEVLTKFADFEPLYNLLIALISIIQPIRLKVLSNLYNNLESNSPVRYDVFVAILNVAAELDAWIA-EWVALNQRRALYLLISQKLEQSAIRAVFEDLFKLQ-AVQ-ALKIF-LDESLKQYTKMRLLSMASLAAAGEVAYDTIAQTLDVPDEVEIWVINVIRAGLMDAKMNQLKRTVVVGRSVRVFSETEWQQLNDKLNAWKANLKDVLQVIS Sporo1 VTEAAKVVTQLLEFEGFSNLVLSFISLADAIRYATLATVFNSLPSSSALRLAVLLKLISYAAQFESYLL-SWGEEE-GNAAVSQIVETLVKKASSLIFASLTTSRFP---SIDIF-QRGDLSSFKKLRLIKLAELCSEETVEYGEIAKA--LDEEVETWVIDAIRASLLTGRLSQPTQSLSITRALRSFESKHWSTIEQRLQSWRKSLDAILASTQ Stehi1 VLELAQVFEAVVETEGFFNLLYAHLRLVEIIKYRTLTNLFNSLPRRSPLRLKVYTTLLTLASSVDKWLS-EWISSEEKIAFLKQLVEAYEKASVKLIFDPLFRID-AVVESARVF-LTGGLEELHKMRLLSLASLGFEQDLPYAKIAASIHVESEVEKWVIDVIRTGLLSGKLSQTTQTLHVIRSTRTFDAPQWELLASRLTAWKAGLEGVLEVVE Tapde11 IDELARAIQAVVNFEPAHNLLIHILNFKK--SYNILTTFFNVSPPS--TRLPVFEALLELSTEVKAWLK-EWASPEEIRSIYGKMAELCSQATMTAVVDELLVLP-PVR-ALSIL-SSGAFVDFHKVRVLNIAALAARRKLRYSDVASALEIGKEVEAWIIEAIKSGLVEGKLSQPSETFLVHRATRAFEHEQWEEVSAKLASWRESLQGILEVID Thetr VYN--DTLMKMIALESSKLPLI---------FGKLVAAAF---------------------------------PVAKKRAGLQLAAKALSSVVLQVVFDHLLELK-AVA-AFSVF-VNGFVTDYEKMRLLSLTSLAANEIIPYSLVSATLDVAEDVERWCIKISKAKLARVRMDQASKVIHISRATRVFEHSHWELLREKLSVWAKATRAMVDVVQ Treme1 VREVAEVVKSLVEAEPAHILLLHLLAVVDAVACRILNNTYNYLSPASSLRPHTLLAILSLLSQLESALT-QWIPSQEKVTFLISAAEIYQTSAEKTIVEEVLRVP-GVSEKLGLFTQTDELEAVRKIKLIALVTLASRRQLQYSQIATALQVPADVEAWVIDGIRANLFKARLSQPSSLVTISSVSRRFGPTEWQLLERRLEEWKKTVSGARTVAA Trire2 AREMAEVLSKLVEFTAASNLMIHLANLSKPLALNALVTVFNLLEPNDPVRARVFQQILKFLKALPEWIE-SWTDAAMARKIYEDVAEVALESSLRALFQDLRAIP-SVQ-ALDIF-AEQDLEDYRKMRLLTFASLAAAREVEYAKITKALQIPEDIEIWAIDVIRAGLVEGKLSQQRQMFLVHKVTRVFGQKQYQELATRVDHWRSTLQNVLGVLQ Umbra1 IVEVTEVLNQIAEAEGALNLVIAILTFSKALKQKILLNLYNTCPSNSRLRYDIFIAIFDAVVKVDVWAK-EWLDLETERALYSHLAEQLKAAISTAIFEDLLQYK-PLQ-QLNIF-LNGNLQEYTKMRLLSLASLGSERELTYGEIAAALEISSEVEMWVIDVIRAGLVEAKLDQLNKTVIVYRSIRVFGKEQWQQLDSKLNSWKNSLTDILAVIG Ustma22 IVEVSQTVQQLVELEGVYNLIFSLIQLLSAVRYRILSNLFNSLEATSALRLQTFNALLSLVAALPQWLA-QWVSETEKASCLESVAKALEGAAERTVFEDLLHVQ-AVL-DLKIF-VGGTTADFHKIRLLDLADLCALADVSYASIAKTLNIEDQVELWVIDVIRAGLVSGKLSQVNDAFRVYKSTRQFGKEQWQSLEQRLVQWQNSISSIIESIA Walse1 IQEIVEILDSLLEIEGFFNLVGYLIELINKLLYKVIYNLINNLSQEYSLRLESYKQLLELSIK---------VSDLNDPHFFLTISNYYDQSSKLLILAQLLELK-AII-NVSIIKLNDD----HKYLLIKLNNYCSNKDIAYDDISTNFRIENRVELLLIELIKSGLTIARLNQSTKTFKVSHSNLMIEQQDWLNIKTNLINIKSNLNKILNVL- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster2908.fasta_al_trimmed; alignment length = 62] Allma1 LPPERGSFPLDHDGECKSIMKDYLACMRSSTKCRDLSKKYLECRMERGLMAPDKMENLG--F Ashgo11 TPPERGSFPLDHEGECTAQMMEYLNCMKNAPNCRLLARNYLKCRMDHRLMDRDEWAHLG--L Aspfu1 TPPERGSFPLDHEGECKHLISQYLKCLKNDEECRKLAKGYLSCRMEKNLMAPDDFKNLGLVF Aurde31 LPPDRGSFPLDHDAQ----MMLYMSCLKSSIPCRVESAQYLDCRMNKGLMERDEWRNLG--L Batde5 IAPERGAFPMDLDGVCGAAVRDYISCVRETMKCRELARLYLSCRMDHGLMEKDDFANLG--F Botbo1 LPPERGSFPLDHEGECQLAMKTYLKCLRDNGKCRELSKAYLDCRMNRGLMERDEWKNLG--F Botci1 SPPERGSFPLDHDGECKSVMQSYLSCMKNDPECRDLAKSYLSCRMDRNLMAKDEFKNLG--F Caeel SAPLKGSFPLDHEGTCKLEMLNYMVCLHQNSECRSTAKDYFECRMNHGLMDKEEWQKLG--Y Canalb1 TPPERGSFPLDHDGECKEYMTKYLTCMKNAPNCRILAKQYLKCRMDNQLMEKSDWDSLG--L Cangl TPPERGSFPLDHDGECAEYMQKYLQCMRNAHNCRLLAKDYLKCRMDHQLMDKDEWKNLG--L Capow RPPEKGSFPLDHEGECKDAMRRFMACMRNSSACRIESRDYLKCRMDNDLMTREDLKQLG--F Catan2 ---KRGAFPLDHDGECKALVQKYLKCLKSNMSCRELSKAYLECRMQRGLMAKDEMQNLG--F Cioin -------------------------------------------------------------- CocheC53 NPPERGSFPLDHDGECKSVMMSYLRCIKNDPECRDLSKSYLSCRMDRNLMAPDSFKNLG--F Coere1 TPPDRGSFPLDHGGECKVVMARYLECLESNKKCRTLSKEYLECRMQK--------------- Conco1 -------------------------------------------------------------- Conpu1 SPPNRGSFPLDHDGECKEAMMEYMKCLKTSTPCRVLSKQYLDCRMTKGLMDRDEWKNLG--L Copci TAPDRGSFPLDHFGGYK--MTLYMKCLRDSSPCRTLTRDYLDCRMQKGLMEKDEWKNLG--L Croqu1 TPPDRGSFPLDHFHDCSSFMKTYLDCLKNQAQCRLESKNYLGCRMEKGLMAKVNWEDLG--L CryneH991 SPPARGSFPLDHDGECKTFMISYLKCMKDNGKCRLFSKQYLECRMDKGLMARDDMANLG--L Crypa2 TPPQRGSFPLDHDGECKQAMSSYLACIKNEDSCRELAKAYLSCRMDRNLMARDDFKNLG--F Debha1 TPPERGSFPLDHDGDCKQQMIEYLKCMKNAPNCRVLAKKYLKCRMDNQLMDESEWDSLG--L Dekbr2 TPPQRGSFPLDHFGDCTEQMKKYMKCLENAPNCRLLAKEYLDCRMKHDLMDKTEWKNLG--L Dicdi TPPDKGSFPLDHDSECSKPMLAYVNCLSLSRFCMEFSKEYLKCRMDNNLMAKEDMDNFG--F Dmel TPPEKGSFPLDHEGLCKKQFLLYASCLRDTSQCRQDAQNYLACRMDNNLMEKTEWSKLG--F Enthi -------------------------------------------------------------- Falba SPPERGSFPLDRTDACRLAMSLYMDCLRDTSKCRDLAQSYLECRMNTGLMEKDNMSNLG--F Fomme1 TPPDRGSFPLDHYGECKEHMKAYLACLQTSTPCRAMNKNYLECRMSKGLMERDDWHNLG--L Fusgr1 -------------------------------------------------------------- Galma1 TAPDRGSFPLDHYGECKEKMQLYMSCLKTSSPCRNLSKDYLDCRMNKGLMERDEWKNLG--L Ganpr1 VAPDLGSFPLDRQGTCKDLMKQYMECLQEGMACRAVTKAYLECRMENGLMRKDDMKALG--F Gloin1 TPPEKGSFPLDHEGECKQFVKEYLECLKNNGNCRHLSKTYLKCRMDKGLMTPEEMKNLG--F Hisca1 TPPERGSFPLDHDGECKYIISSYLRCLKNDETCRKLAKSYLTCRMDNNLMAPDSFENLGLVF Klula1 TPPERGSFPLDHDGDCTKQMQEYLSCIKNAPNCRLLAKEYLKCRMDNKLMDRDDWKHLG--L Lacbi2 SAPDRGSFPLDHYGECKETMNQYMNCLRTSSPCRVLSKAYLDCRMNKGLMERDEWKNLG--L Lenti61 -------------------------------------------------------------- Malgl1 -------------------------------------------------------------- Mellp23 TPPDRGSFPLDHFHDCSSFMKTYLDCLKNQAKCRLESKNYLGCRMEKGLMARVNWEDLG--L Mnele -------------------------------------------------------------- Monbr -------------------------------------------------------------- Morel2 PPPDRGSFPLDHDGECTVFMKEYLNCLKNNGKCRHISKQYLSCRMDKGLMGNDDFKNLG--F Mucci2 KAPLRGSFPLDHDGECKTFMKDYVKCLKNNGLCRQFSEAYLQCRMDNGLMDKDDMGNLG--F Mydma -------------------------------------------------------------- Neucr2 TPPQRGSFPLDHDGECKHVMTTYLACIKNEDECRSLAKAYLACRMERNLMAKDDFKNLG--F Orpsp11 -------------------------------------------------------------- Pench1 SPPERGSFPLDHEGECKHIISGYLKCIKNDEACRKLAKEYLSCRMDKNLMAPDNFENLGLVF Phybl2 APPLLGSFPVDHDGECKDFMKNYVKCMRNNGACREFSKAYLQCRMDKGLMDKDNMDNLG--F Picst3 TPPERGSFPLDHDGECTEYMTKYLQCMRNAPNCRILAKQYLGCRMDNQLMEELTWDSLG--L Plicr1 APPDRGSFPLDHDGECKSQMMLYLDCLRTSTACRVLSKEYLNCRMNNGLMDKDDWKNLG--L Polpo TPPDKGSFPLDHDKECTEPMNAYLKCLAQSRQCAELSKFYLQCRMDKGLMAREEIENFG--Y Pucgr2 SPPDRGSFPLDHFHDCSSFMKTYLGCLQDQSKCRVESKNYLGCRMEKGLMARVGWDELG--L Punst1 SPPDRGSFPLDHEGECKNQMMLYLGCLKDSTPCRLLSKDYLDCRMTKGLMAADEWKNLG--M Rhior3 KAPLLGSFPLDHD---------------NNGLCRQFSKAYLQCRMDK--------------- Rhoto1 APPLKGSFPLDHDGECKDYMVRYLKCMKQSTECRYLSKEYLACRMDKGLMERTDFEALG--F Rozal11 KAPIRGSFPLDTQGLCKDYFENYMACLSHSILCRRGMRDYLKCRMDNDLMDKEDMARLG--F Sacce1 TPPERGSFPLDHDGECTKYMQEYLKCMQNAMNCRLLAKDYLRCRMDHQLMDYDEWSHLG--L Salro TPPDKGSFPLDHDGECKQSMKVFLECLRNGRKCRVESKAYLQCRMEKQLMAKEDWAKLG--Y Schco3 NPPDRGSFPLDHYGECKDYMTAYMGCLKDSTPCRPLSKNYLDCRMRKGLMEKDEWQNLG--F Schpo1 EPPERGSFPLDHFGECTHVMKQYLECIKNQEECRLLAKKYLQCRMDTGLFGKDDMKNLG--F Sorma -------------------MTTYLACIKNEDECRSLAKAYLACRMEHNLMAKDDFKNLG--F Sphar -------------------------------------------------------------- Spipu1 -------------------------------------------------------------- Sporo1 --PLKGSFPLDHDGECKEAMMKYLKCMKQSTECRPLSKAYLACRMDKGLMERTEWEMLG--F Stehi1 SPPDRGSFPLDHWGECRDTMMVYMECMKASTECRHLSRDYLDCRMRKGLMDRDDFKNLG--L Tapde11 -------------------------------------------------------------- Thetr -------------------------------------------------------------- Treme1 SPPDRGSFPLDHDGECKNFMLQYLQCLKDNGQCRLESKRYLLCRMEKGLMEKDDMANLG--L Trire2 -------------------MMSYLSCMKNEDECRNLAKAYLTCRMDRNLMARDEFKNLG--F Umbra1 KPPALGSFPLDHEGECKDFMKEYIKCLRNNGACREFSRAYLQCRMDNGLMAQDDMKNLG--Y Ustma22 SPPERGSFPLDHDGECKSVMQEYMNCIKDNGKCRHLSRAYLQCRMDKGLMEQDNMDNLG--F Walse1 TPPARGSFPLDHDGDCTKPMKEYLKCLKNNGACRELSKSYLKCRMQNGLMENDNFDNLG--F Zygro1 TPPERGSFPLDHEGECSRQMQEYVECLKNAPNCRLLAKEYLKCRMNHDLMDKDDWKNLG--L [Cluster2909.fasta_al_trimmed; alignment length = 222] Allma1 DHDHYLASL-FLP--SNLRALRAFN-YELAIRDNARTLGRIRFQFWRDTVDKI--YGNPPEQPIAIVLAAAMHLKRIINGREENFLTYSSIDALEEYAESTASALLYLGVKSIDHIASH--IGKAQGIATLLRGTPLPSDVCAKHSVVTEKVMRELSAAVFEIATRANDHLITAR--SHMAFPALMP-AIPWLQRLE--KHDFNLFSRV-HRDA-LLPLSLW Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 DRPSYTLST-FIP--RKSQALRALN-VTLSIPETTSTIGLMRLQFWRDAITKI--FGSPPKEPIAILLASAITLNKMINAREQTLTNYPTIAALETYAENTYSTLLYLPMTSADHVASH--IGKAAGIAAVLRGLPLPLDVMAQAGVKEEDVFRGLRDAVFTVATRASDHLITVQ--QMLAFGVFMP-AVSWLDRLE--KVDFDIFPEL-LSDW-RLPWKAY Aurde31 DYASYIAGRAIAS--ADTRVLRAFA-VELAVPEMVSTLGKMRYQFWRDALRP----ARPPQHPLAQALHPLIGLKRIVDARDADLGRYPDTGALTTHCESTTSTLLYLPPSAASHVASH--VGVAAGLATLLRALPLPVDLTAKHGVTHEDVFRGVSDAVFALATVANDHLLTAR--DMLVAPIIAAPGVPYLERLE--KENFNAFPSL-QRDW-KLAWRMW Batde5 DYEQFLITL-FTP--EFARALKAFN-VETAIRDAVTNIGSMRIQWWRDAIEKT--FGSAPNHPVMMALAKSLEFTKILAAREANLRDHTTIADLEAYSENTMSSLIYLGVTDAEHAASH--SGKAIGITTALRSTPLPTEIMAQHQVVTEDIFRHLLDAVFTIATRANDQILTAR--SFSAIPALLP-LILYLTNLQ--KANFNVFPSL-QKSL-FLQFYIW Botbo1 DNDAFLCSY-FYP--RHLQGLRAFN-VELAVKENVSMIGQMRMQFWRDAVKGI--SDKPPNHPIALALHAASKLKRMIDAREQDLQNYMTVESLQNYAESTSSTLLYLSLSSLSHAASH--LGIAHSFATLLRAMPIPAEITSKHGVTQEEVVRGIDDAVYEFATLANDHLITAR--ESFAMPIFLT-GIPYLSRLE--AVNFDAFPSL-QKDW-KLPFQIW Botci1 ------------------------------------------------------------------------------------------MDALEMYAENTYSTLMYLPLQSADHVASH--IGKAAGIAAVLRGLPLPLDVMAETGVKEEDVLRGLKDAIFTVATRANDHLITAR--EMLGFGVFMQ-AVPWLEKLE--QLDFDVFPEL-RREW-KLPYKAY Caeel DIDSYLAIL-TIN--KRAQALNALN-VELAIRDKVDASAMYRLQFWKDAISSI--YLPVPRQPVAIALCSFAALLKLVETRQSTIGDFSDINALCEYGKSTIGSLLCLARNSAYDVAKD--LGAAYAIANMIRATHLPADVMSLNGATPDSLYKEMVGMTKDLVNESKRLLIDAR--SPIVRPALAATGATIIKTIE--KNNYDIYPHL-QRNP-LLLWSLL Canalb1 DRSSYILAQ-YIP--EPVRAIRAFN-LEINASSQMSSTADLKFKFWSDLILRV--FETDLGEPIAILLRDGLKFQQFLQTRIK--NNFQTVNDICSYGEGTFSQLNYIRLLEMSDIAAH--IGQATAVSSMILGVPLPVDLMTSSGLSQESLLRALKNVVYETAITANDHMLTAK--SKLLYVPTMA-GIPFLNKLE--KCNFDLFGRL--KEW-RLPMKSF Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow DYEHYLETL-LLP--KRARAVRALN-VEVAVSDVTTHAGRIRLQFWLDAVAAA--AQGTPHHPVAQALQNVYKVSRLIEERTKLLDDFGTLQDVETYGENTYSGLLYMGIQSADHAASH--VGKAEAIVTLLRATPLPMELTAKHGVVQEDVVRALQEVAYELASSAHVHLQTAQ--AMATAKVLLP-AVPFLERIQ--QADFNLFPSL-QRNP-MLPFSLF Catan2 DHDHYLASL-FLP--ANKRGLRAFN-IELAIRESVRTLGRMRFQFWRDTIDSI--HGQTPNHPVAVMLAAGVHLKRVVNGRQDNFLTYPSIDAIEEYAESTASTLMYQGVKSIDHIASH--LGKAATMATLLRGTPLPADVCASNGVVVEKVIRELSSAVFELATRANDHIITAR--THVAMAALLP-VVPWLRRLE--KADFDLF---------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 DTPSHILQT-FIP--QSSRAIRAFN-VDVAVADTTSTIGMMRMQFWRDTITKA--LGAPPKEPVAILLAQAAEFHRIINTREQYLGNYPTLSALESYAENTYSTMLYLPQASTDHIASH--IGKAMGIAAVLRGIPLPLDVMAEASVREEDVFRGLRDAVFTVATRANDHLITAR--EMLAFGVFMP-SVAWLDKLQ--GVDFDIFPAL-RVDW-KLPMKAY Coere1 DYDNYLVSL-FSP--KQARGVRALN-VELVVSEKTTAAAQMRYNYWDTTVKSL--YSSPTQTPIGRVVYDAIQLRRLVSEREKSQRRFMTVGDVEKYGERAYACLIHLGVRDADNAARA--IGIATAIMNFTRSLPLPLDIVERHKVNMDALYGALQEAVYEFATIGYTRLCGVA--EIYAFPGLLA-AVPWFERLE--RADFNVF---------------- Conco1 DYDSYLIST-FLD--PRTRSIKALS-IELAIRDQVTQLALVRLQWWKERLDGL--KDQVSEHPILMLLHHTLKFNRIISQRIEHTQNFSTLEELENYTENTVSSELYLKIRDIEGLLSH--LGKARGIVTLLRGLPIPDQLLAQYNISQEQLFRPLRDAIFEIATKANDQLLTVN--YLLAFPLFLS-SVPYLNQLE--KANFDPYQSL-HRDW-KLVGKLA Conpu1 DYEGYLTSK-FYP--RHRQALRAFY-IELAVQESVSVLGQMRMQFWRDAVKDS--AGKPPRHPVALALHDNITLKRIIDARDNELQNHLTMDSLTSHAESTASTLLYFSLTSLSHAASH--VGIASSLATLLRALPIPAEITAKHGVSQEEVFRKLEDAVFEFATIANDHLLTAR--EMFAMPIFLT-AVPYLKRLE--VANFDAFPSL-KRDW-KLPWHVW Copci DYESFLTSP-FYP--KAKQAIKAFA-VELAVQENVSMIGQMRMQFWKDAIKDI--GGKSPKHPIALALLRASEFKRIIDARTAELETHLTIETLTSHAESTSSTVLYLSLPSLSHAASH--LGVAQSFTTLLRALPIPAEITAKHGVNQEEVFRGLEDAVFEFATIANDHLITAR--EMFALPIFLS-GVPYLSRLE--KANFNAFPQL-QRDW-KIPFKIW Croqu1 DHASVLQIP-FYP--PNARAIKALN-AELNIPGSISMIGQMRYQWWRDAIDTC--YKVPTNHPVITALRIAIEFSRLIDARQANYLNFASVEKLISHSQATNFSMLALGNSPIDHALHH--LSNAITLATLLHAFPVPPEL-----CSEEDLFRRVQQTVIRIATLAWSEFSACR--DALIRPVFLA-ATPYLGRLE--AVHFDTFPSL-QRDW-KLPFQIW CryneH991 DPEAWLCSY-FWP--RREKAWRAFN-LELHISANVSALASIRFQFWRDALKGI--FQNVPQHPVAVLLADMKRLSQLIDAKPAAVSLHLSLNSP------LSTSLLLTHASSISHTLSH--VSTLLTVVSLLRNLPIPADICEKYGIVEEELFRGFRDACWEIGTRGMDELITAR--RDLVMPIFLS-AVAYLKRLE--KYDFDVFPDI-QHDW-TLAPKIW Crypa2 DYDAYLIRQ-FVP--RSAQALRTLN-LELALPETVSTIRQLRLQFWKDTVNKT--FGNPPREPISILLHKNITLLRFINTREAFMDNFTNLAALEDYAENTYSTLMYMGMRSMDHLASH--IGKACGIVAVLRGVPLPLDVMAEVGLREEDVFRGLQDAIFKVATRANDHLITAR--DMLGFGVLLE-AVPYLERIE--KANFDPF-QI-RNSW-KLPWRIW Debha1 DRSSYILAQ-YIP--EPARAIRAFN-LEINASNQLSSTTDIKFKFWSDLLSRV--FEKNLGEPIAILVRDALRFHQFLQTRLQ---TFQTVNDICSYGEGTYSQLNYISLLEVSDIAAH--IGQATAIGSMILGLKLPIDLMTKFDLSQESVLRKLKNITYETAVIANDHILSAR--DKLVFTPFMV-AIPYLQKLE--KYDFDIFPKL-QQEW-RLAWTSF Dekbr2 ---------------------------------------DIKLAFWSEQVEKCEQLIKGLNDPTSILLADTILLRQMIFTHSHEEKVFTELDSMCSFGEGTYSQMNYVGLLESSDISAH--IGQATAICSFIIGLKLPIDILVKHAISQEDTIRKLKAAIFDVTTRANDHILAAR--QKLIYTPFMC-AIPYLERLQ--KYDFNVMPRL-QREW-KLAWRAY Dicdi DKENYINSL-LIS-DPIARAIRAFN-IETVDHSPKSKISRLRLSFWKDAINNI--YGKVYDQPLTRVLAQVIKFIKILNRREKDNQQIKDMEELEQYADDIHSSLMLLGVKGVEHCASH--LGKAIGIMVLIRGTVIPVSLTTKYGINVESLYRKLQNAIYEMASCAKLHLDKAK--QFRATEAFLS-VSVFLERLR--KADFNIFPNT-QHPL--LLIKLY Dmel DYENYLCTL-LLP--RELRALRAFN-VEVSVSGHQIQIAKMRLKFWHDSIDKC--FSYVEDQPVLRELKHTVGLRRLVTAR------FESIRELEEYTEQTFSSLLLGGVRDADHAASH--LGKAQGIATLLRSIPIPLEVLVLHGVSQERIIRGVEDCIFDVASAANTHLKLAR--QLHVRKIFLS-AVAYLERLR--RANFLLTKSC-VRDT-LLPARLF Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba DYEAFLATH-FFPAPASTQAIRCLS-LEASISSAATRLAEIRYAYWREVIGAI--YISAQQHPIAVTLRAFHRLARLVDERKRHAAGFGSLDELERFGENTSGTVLSLGAGGAEHAASH--VGQAAAIVNVIRAMRLPVDLVMKHNLREEAILRELCDAVFELATRANDHLITAR--TMVSVAVLAGVAIPYLDTLALPAVQFDPFPSV--HRWLKTQF--- Fomme1 DRDSYLTSQ-FFP--KALQAVRAFY-LELAIQDSVSLIGQMRMQFWKDAIQQ----GASP-HPIAVALHNASKLRRIIEARDIELNSHLNMDTLLAHAESTTSTLNYLGLSSYSHAASH--IGVSQTVSTLLRALPIPASITAKHHVNQEEVFRGLQDAVYEFAIVANDHLITAR--DMFAMSVFLN-AVPYLRRLE--KANFDAFPKL-QRDSIRLPWQIW Fusgr1 DYDAHLIRR-FVP--SPVQVLRTLN-LELVLPELVSTIGAFRMKFWQESIDNT--FGRPPREPICILLHKCLQISRLIKTREKHMSNFATLSSLEEYAENTYSTLMYLPLKSVDHLASH--IGKACGITAILRGIPLPLDAMAEAEVKEEEVFRGLQDAVFQVATRANDHLITAR--EMLGFGVLLE-AIPYLQRLE--QADFNPF-AV-KAGW-KVPWSIW Galma1 DYDSFLNSY-FYP--RDAQAIKAFS-VELAVQDHVSMIGKMRMQFWRDAVKGI--SGRPPKHPVALALYEASQLRRIVDARDTELQTHLTIDSLTSHAESTSSTVFYLSLSSLSHAASH--LGTTQTFATLLRALPIPAEITAKHGVSQEDVFRGIEDAVFEFATIAHDHLNTAR--DMLAMPVFLA-GIPYLKRLE--KAGFDAFPKL-QRDG-LLAWQMW Ganpr1 DYEQYLISL-LQP-SPSVRALRALN-VELAVRETVSQLGRIKMQWWRDAIDGC--FGNPGQSPTMIALYRAMQFVRLVRERSANLSVYPSLASLEQYAEHTASSLLYLRVQSADHAASH--LGKAVGISTVLRGAALPADIMAKHGVSQEAVFRALSDAVLEIATLAHAHLRHTR--ELISLPAFLS-IVPFLKRLE--DVDFNLFGRL-YKDW-KLPAVMW Gloin1 ------------------------------IRESTTQLGNLRMQFWRETIDKT--FGIPPQQPIAQVLYNSLEFKRIIDERDAQLYDYINNKDLESYGENTASCLLYLGVEDADHAASH--IGKSIGIVTILRGFPLPSAITSKYNISQEEIFRGLEDAIFEIATLAHDHLLTAR--TFLALPALLS-AVPYLKRLE--KYNFNVFPKL-ARNW-KLPFYLW Hisca1 DRPSFTLSA-FIP--RQTLALRALN-VSLSIPDTTSTIGLMRLQFWRDTITRT--LGKPPKEPIAILLASALSFLRMINSREQYLTNYTSISALESYAENTYSTLLYLPLTSADHLASH--IGKAAGISTVLRGIPLPLDVMAETGLKEEDVFRGLRDAVFTVATRASDHLITAR--QMLSFGVLIP-AVSWLDRLQ--AVDFNIFPEL-RFDW-RLPWKAY Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 DYESFLVSH-FYP--KAAQAIKAFS-VELAVQDNVSMIGQMRMVFWRDALKAI--AGRPPKHPIVLALYEASQLRRMIDARDAELHTHLTIDSVTSHAESTSSTVLYLSVGSLSHAASH--LGAAQTISTLLRALPIPAEITAKHGVKQEEVFRGIEEAVFEFATLANDHLITAR--DMLAMPVFLS-GVTYLGRLE--KANFNAFSRL-VRDW-KLAWQIW Lenti61 DYESYLIGS-FYP--RELQALRAFY-VELAVQDTVSMIGKMRMQFWRDAIKSM--AGRPPQHPIAIALHDASRLRRIIDARDAELHTHLTVESLTAHAESTTSTFLYLNLSSASHAASH--LGVAQCIHVLLRALPIPAELTARHEVRQEDVFRGISDAVFEFATVANDNLLTAR--EMFVMPVFLY-GLPYLGRLE--SVNFDAFPSL-QRDW-KLPWKIW Malgl1 DYAAYLTHV-AYA--RRVQALRAFQ-VELAIKDTVSLVGRIRMQWWRDAIESI--YGRPPKHPIAQGLYEAISFLRIIDAREADLADPPTLEELEKYAEATSSRMLYQGLSEVDVLFSH--LGKAIGLTIFVASLPLPLEYILEAGVTQEDVFRGLKDAVFYTATRANDYLITAR--RVITGPMLLA-VQPFLRKLE--RVDFNPYPTL-ARDW-LLPWHMW Mellp23 DHSSVLQIP-FYP--KDVRAIKALN-LELLIPNSISLIGQMRYQWWRDAINTC--FQAPINHPVILALHPVIKLNRLIDAREKSYLNFNTIDDLIKHSQSTNFSILSCNLSSIDHALSH--LSNLLTISTLLHSLPLPIDL-----CSEEELFKRVQQTIMRIFDLASSELNACR--ATLIRPLFLS-ATPYLNRLE--KLNFDAFPSL-QRDW-KLPFQIW Mnele DYEHYLCVC-LAP--LGTRALRAFN-VELSPYSSASEVNRLKLLWWRDVVEDL--YRVTHNSPVVLELGALIRLMKLIEAR-----NYNSLQDVEQNSENTHSALNFLGYKTTDHAASH--LGRCEGHISLIRSIPVPSTTLARTGVSQSDIVRKIRDVVHDIASSAHLHAEHCE--ELSALYGLLP-LTPFLKRLQ--KYDFDIFRTL--RPP-SLPFALM Monbr DRDHYLATL-LLP--STAQALRALN-IEVAIRDSARATTSMRFLFWKDAIDAL--FRPLPQTPVMQELETLQQLRRLIMAREKDS-DFASIPQLERYAEDTASTLLYMHIRNAEHIASH--IGKAQGHVTLLRGLPLPVELCAHHGLRAPTVLRELQDVVHAVASNAVRHLNTARLEYQAAASAYLP-AVAYLDQLL--KADFNPFPNL-ATSG-LLPFRMG Morel2 ----------------------------------------MRMQFWRDSLDKI--FGVPPQQPVALALAYAIQFKRMITEREQNLSDFMTLAQMETYCENTFGSLLYVGIKSADHAASH--MAKAMGIATMLRAFPIPAEITAKHNLSQEALFRALQDATLEVATAAHVHLATAQ--SYMALPVLMA-GIPYLTRLE--KADFNPLPNI-QREW-FLPAKLW Mucci2 DYEGYLCVP-FFP--AHLRAIRAFN-VELAIRENVSEIGKMRMQFWKDTIDKI--YGHPPEQPIALALSEALKMKRIISER-----------DMEDYSENTQSSLLYLGVKDADHAISH--IGKMIGITTFLRALPLPAEITAKHNLVQENVFRGMEDAVYDVATAAYDQLLTAR--SLLAFPALLS-AIPYLENLE--KANFNVFVKL-QKDW-KLPLVMY Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 DYEAFLLRQ-FVP--PSSRALRTLN-LELALPETVSTIARMRMSFWRETVNSV--FGNPPREPISILLHQAIQLLRLINTREQHMENFVSLNSLEDYAENTYATLMYMPLRSMDHLASH--IGKACGIVATLRGIPLPLDVMAEVGVREEDVFRGLQDSVFKVATRANDHLITAR--EMLGFGVLLE-AVPYLERLE--KADFDPF-KV-KASW-KLPWRLW Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 DRPSYTLST-FIP--RHAQALRALN-VSLSIPDTTSTIGLMRLQFWRDSVTRI--LGTPPKEPVAILLASAISLTRLINSREQTLTNYPNIAALESYAENTYSTLMYLPMASADHVASH--IGKAVGIAAVLRGLPLPLDVMAQAGVKEEDVLRGLRDAVFTVATRASDHLITVQ--QMLAFGVFLP-AVGWLDRLE--KQDFDVFPNL-LSDW-RLPWKAY Phybl2 DYEAYLAVS-FFP--SHLRAIRAFN-VEIAIRENVSTIGKMRMQFWKDTIDNV--YGKPPQQPIALALAESLKFKRIITERTTNLDDFMTIQDMETYSENTATSVLYLGLRDADHAISH--MGKMMGITTFLRSFPLPAQITAKYGISQEDLFRGLEDAIFEVATAANDQLLTAR--SMLAFPVLLA-AVPYLEKLE--KANFNVFPSL-QKDW-KLPLSLW Picst3 DRSSYILAQ-YVP--EPARAIRAFN-LEINASSQLSSTADMKFKFWSDLVARV--FEKDIGEPIAILLRDALRFHQFLQTRLK---SFQTVDDICSYGEGTYSQLNYISLLEVSDIAAH--IGQATAVGAMILGMNLPVNLMSKYDLSQESVLKKLKNIVYETATTSNDHILTAR--AKLIFTPFMV-AIPYLNKLE--KHDFDIYHKM-QKEW-RLAWTSF Plicr1 DYDSFLIAQ-FWP--KELQALKAFA-VELAVQDVVSVLGQMRMQFWRDAVKSI--SGRPPRHPVALALYETSQLKRIIDARDAELSTHLSLDSLTSHAESTSSTLLYLNLNSLSHAASH--LGAAQTITTLLRALPIPAELTARRGVVQEDVFRGLEDAVYDFAVEAHAQLSAAR--DMAAMPVFLA-GVPFLGRLE--AANFDAYPGL-QRGW-NLPWQVW Polpo DRENYVCSI-LIS-DELARAIRAFN-IETVHSEVKSRLAKYKLSFWKDAINNI--YGKVYDQPLIRVLAQQIKFIRLLNRREKDLNSMKDMDELEAYAEEIHGSLLLLGVR-AEHAASH--LGRAMGIMTLIRGTPIPASLTTKYGIVTERLYQKLKEAIFEMASVAKIHLEKAR--SF-AHEAFLC-AEFFLERLR--KSDFNIFPTL-RRIL-------- Pucgr2 DPESVLQLP-FWP--KESQAIKSFH-GEINIPNAVSLIAQMRYQWWRDAIDSC--YQIPSNHPLIHLLKPIIKFARIINASETHYLDLPTLTALADHSRSTTYASLSLTSSKVDHSLSH--LALFLTVVRILKQLPVPLEL-----CSEETLFRDAQDSLFNLIFLAWSELVAAR--EVILIPLFLP-ATPQLTKIS--NIILNTHARR-QADW-TVPFKLW Punst1 DYEGYLTSP-FYP--GEAQALKAFS-VELAVQEAVSMIGKMRMQFWRDAVKNL--TGRPPQHPIALALHDASRLKRIIDARDSELDNHLTLDSLTSHAEATSSTLFYLRLSSLAHAASH--LGAAQTIAVLLRALPIPAEITARHGVSQEDVFRGLEDAVFEFATAANDHLLAAR--DMFAMPLFLG-GVPYLSRLE--AVNFNPFPSL-QRHW-KLPWNVW Rhior3 ----------------------------------------MRMQFWKDTLDKI--YGKPPQQPIALALSEALKMKRIINERTSNLDDFMTIKDMETYAENTQSSLLYLGIKDADHAISH--IGKMIGIATFLRALPLPAEITAKYDVSQENVFRGMDDVVYDVATAAYDQLLTAR--SLLAFPVLLS-AVPYLENLE--KVNFNPFPLL-QKDW-KMPLVLW Rhoto1 DHESIYASY-FYP--SSVRALRALN-VELALPDQVSLVGRMRFQWWKDAIKGL--YGRPPPHPLLNLLSQLPQFTRLISTREANFMNFHSLQDLADYSAGTQASLLYAKEADLDHAASH--LAVAITIATLLRSIPIPLEVAARHNLREEALFRGLQDAVAQLAGIAEAELRTAR--ECFAVPVFLS-ATPYLARLASPKIDYNPFASL-HRYW-KLPFQVW Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro SREHYLTTM-LLP--RTAEAVRAFN-AQISVRDEARGAVKMRFLFWNDVVNGL--KSALVAHPVAKALDI--TLKQLVRAREAHSDDFQTMKDAENYAEHTCSSLYYMGIRDADHVASH--IGRAEGLVTLLRGLPLPLDVCAKHGVVQQDVLRAVQDAVHAIASEAVLHLNTAR--SMMARTCFLP-SVCYLNQLL--AVDFDPMPTL-LPQG-LLPLRLL Schco3 DYESYLIGQ-FFP--QERQALKAFA-VELAVQDNVSTIGRIRMQFWRDAIKGI--QGNAPHHPVALALAKAMQLKRIIDARDNELMTHMTSESLVAHAESTSSALLYLSLSSLSHAASH--LGVAQTLAILLRALPIPAEITAKHGVRQEEVFRGIEDAVYEFATLANDHLITAR--TTLAMPAFLT-GVPYLQRLE--KANFNAFPKL-QRDW-KLPWHVW Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma DYEAFLLRQ-FVP--PSSRALRTLN-LELALPETVSTIARMRMSFWRETVNSV--FGNPPREPISIVLHQAVQLLCLINTREQHMENFVSLNSLQDYAENTYATLMYMPLRSMDHLASH--IGKACGIVATLRGIPLPLDVMAEAGVREEDVFRGLQDAVFKVATRANDHLITAR--EMLGFGVLLE-AVPYLERLE--KADFDPF-KV-KASW-KLPWRLW Sphar DAEHFLSSL-WLP--ADIRAIRAFN-IEVAIREVTSQIARIRSQWWRDSLGFV--YAKDPGHPVLKELAKAVHLERLIREREKRFDEFMSMDEVEDYSEGINSSLLYVGVSDADHAASH--LGKTEGIITLLRGVQLPMDQLLAAGVSQEEVIRAITEVAYTISSQANSHLEMAR--EHTAKRVLLP-AVAFLTRLQ--KEHFNLYKTL-DPHA-SLPFRLL Spipu1 DYENYVATL-FIP--PAARAVRAFN-VETAIRENVKNLGKMRIDWWRDAIEKT--YGRPPNHPVTMLLAHSMDFKRILTAREANLQDYPTIKDLENYAENTASSVLYLGIRDADHAASH--VGKAGGITTILRGTPLPSEIMAKHSLSTEDVFRELEEVAFEVATTANDHLITAR--SFLALPALLA-AIPYLQALE--KANFNLFVKL-AWKM-L--YKLW Sporo1 DPEAIYASH-FYP--AHLRALKAFN-VELALQDQVSLVGRMRYQWWKDAIKGV--YNKPLPHPLTTLLASLPQFNRLINAREAHFLNFNSLQDLADYSSGTQASLLY---ADLDHAASH--LAVAMTISTLLRSIPIPLEVSKLHQLQEESLFRGLQDCVATLAGIAQAELRTAR--ECFATPVFLS-AVRSL-------LSFEP----------------- Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Tapde11 DYPSFLLST-FQP--QRSLALRALN-VDLAIPDNVSTVGKMRYQFWTESVDKA--FGVPPAQPVAILLNHVLEVLRLIAERERRIDNFPSLSGLESYAEKTYSTLLYLDIRRIDDIAQH--IGLAMGITSTLRGFPLPTDICTAHNLRQQDLLRGLQDAMFEVATRANDHLISAK--VKIANAVFLN-AVPFLERLE--SYNFDATPKL-MKEW-KLPYRLW Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 ---------------MRDDSYESFHTLELHISTTLTALAAIRYQFWRDALTSA--FGSVTQHPVIILLSDMAKLSQGTR---NVIRDHLHFAS--------------YKQTTMIHLVWRWKLDSLKFFVTLLRSIPIPSDVCARHAIVEEEVYRGVRDACWEIGTRGMDELITAR--RDLAMPLFLH-AVSYLHRLE--SYDFNVFPDL-QHDW-RLAPRIW Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 DYENYLCIP-FYP--KQVQAIRAFN-VELAIRESVSMIGKMRTQFWKDTIDKT--FKKPPQQPIALALSDALQFKRIINEREENLEDFMTIKDMEKYAENTASCLLYLNVRDADHIVSH--IGKMIGITTLLRSIPLPAQITANHNIVQEDVFRGLEDAVFDVATAAHDHLLTAR--SMLAMPVILS-AVPYLAKLE--QHNFNAFPKL-QRNW-KLPLDIW Ustma22 DHPSYLAHH-FYP--KHLQAIRTFN-VEIALKDTVSLLGRMRMGWWRDAVQGA--YNRPAKHPVVLALRDAFQFLRIIDVREADLSDPPTLESLESYAESTSSRLHYLGVRSIDELFSH--LGKVSGLSLAISSIPLPREFLHLHKVVEEDVFRGFRDAVFALATRANDYLITAR--KIIVIPALVG-VVPYLERLE--KADFNPYASLQSKHW-RLPWDMW Walse1 DYPAHLCGY-FYP--KYALALKAWN-IELAIKDSSSFIATLRLQFWKDTINNV--YGKITNEPVATALFDSVQFMNVIEGRERELSLPRDLQSLGTVLELTQSSLLHDPLEKYQLALSH--IGKSIGLATLLRALPIPSDINANHGVVEEEILRKLSDATFEFATEANDQLIAAR--SLLLMPVFLS-AVPYLNRLE--KYNFNPFVNL-QRYW-KLPWEVY Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster2915.fasta_al_trimmed; alignment length = 94] Allma1 MVKLSNYQEDQTTDYGSDAESDEGLLDRIAALKDIVAPETRYAISSKVASAASLGNAAWVISTTALIMLAPLVMELEKETQMVMFEKERDQSAQ Ashgo11 MVELTEITEEDDEAYSSDEEDNETLYDRIVALKDIISPKQRKRLSQAYSTTVWGGNVVWALTTSALLLGVPLSLSLLAEQQLIEMEKNQKDANE Aspfu1 MVKLTEVEDEDTESEISVE-SGETLYERVAALKDIVPPSTRRQISSTVSTLTSSGKALWILSTSAFLLGVPWALAYAEEEQYVQMEREIKGANE Aurde31 MVKV-EIVGEGSSDSLSSASEPESLVDRLAALVDIVPPQTRHSISTRVARTADLGNVVWVLTTSALLVGLPLALALEDESKIVQQEREQQQGVQ Batde5 MVQLTEVTASEDDDLFEAAEEEESLLERLAALVDIVPPTARAHMCNTVATTFDLGSAAWVIATGGILVFLPLALSVEREQVAIMQDQQQQQVAQ Botbo1 MVKVEEVTDAASTDSLASDASEETFLDRVSALVDIVPPSTRASISSKVSRTVSVGNIVWIFTTSALLVGLPLALALEDEAKIVQQEKEQQQGAE Botci1 MVELTEVEDEDTDSEISSDEEEETFADRISALKDIVPASTRTFISNKVDATTSGGKTLFVVSTSALLLGVPWALAFVEEQQVVEMEKEREMGGE Caeel ---------------------------------------------------------------------------------------------- Canalb1 MVKLTQIDDEESDDDDESDLDNETLLERIVALKDIVPPEQRESIYNLSSTIGDGGKFLWTLTSSSLLLGVPLALAILSETQLQEMERGEKSAQD Cangl MVELTEIKEDEDEEDDSDFEDNETLLDRVKALKDIIPPQHKNRICAVFSTSCSGSGLAWTLTTSALLLGVPLSLSILAEQQLIEMEKTQKDAND Capow MSGIVELNEEEDEDEDDSKQLPESIGERLAGLKEIIPAGPRNAIYSAVTLSTWSGKIAWVVGTSALITLVPLGLEVEAEQQFVMWEAETMMQQQ Catan2 MVRLTDVPDHYSTDYDSDAESDESFIDRLAALADVIPPHVRYSVSSKLASLGSLGRAAWVLSTTALVMVAPLVYEMEKETHIEILEREREQSTQ Cioin ---------------------------------------------------------------------------------------------- CocheC53 MVQLTEVTDEDSDSDTSSVHSDETFFERLSALQDMIPASTRRSVSSKASTISSGGKTLWVVSTSALLLGVPWALAYSEEQMIVEQERAAQRAQN Coere1 MVKLVEIEDETTDAESESVDSDESLLERLVALKEIVPASQRHAISRTASTIGYVGKLGWVLTTSALLVVFPLALETDREKMMQQWESELQQNGG Conco1 ---------------------DESLLDRIYALKDIIPPNQRLAISNTVSSVYNIGKTGWVLSTSAFVVLLPLMIAYEKDQELLMRSGQMEQGAQ Conpu1 MVKV-EIVEENSSESLSSVASDETLYDRLTALVDIVPPTTRQKISNKFSSAASMGNVVWVVTTSTLLVGLPLALILEDEAKIVAQEQEQQQGAQ Copci MVKV-EIVDDNSTDSLSSVESDETFAERLAALVDIVPPTTRHSIRSKISKTASFGNLVWVVTTSALLVALPLALALEDEAKIVAQEKEQQQGA- Croqu1 ---IEELKAEESDNSSDSDPSDETVWDRLYALRDIISPSTRAGLGETWDQLCNMGNFAWVVTTSMILIGLPMALSIEGESMLVAHEKEQTQGQQ CryneH991 VVVVEEVRDEETDSEVSSTISDESFYDRVAALKDIVPPQTRSSLYNRYKSTTGAGSLAWLVSTSALLVGLPLALAIEDEARVVAQEKEQSAGQQ Crypa2 MVQLVEVEDEDTDSEISND-SAETLADRLLALRDIIPPTTRSWFYGKYQTTRRAGRSMWSISVSALLIGVPFALCWAEEQQMIAMEQEREQGQD Debha1 MVKLTQIDDEEASDSDSDIDDNETLLDRIVALKDVIPPQHRTQIVSAGETIKDSGNLLWTLTSSALLLGVPLSLAILAETQLQEMEKEQQSAQD Dekbr2 MVSLTEVKENDSDSDDDDFDDDETLAERISALKDIFPPQLRSSVVSGADALQSFGVSLWYLTTTALLLGAPLALSILHETQLSELEKEQQSSSD Dicdi ---------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------- Falba VVEIATVEDEEESDDDDDDDDRETFVDRVVALRDIVPLNVRRQIGDVISPVTGAGSAAWFAGTFAAVVFIPFVLSMDRENMAREQEEREQRS-- Fomme1 MVKV-EIVDEGSSESLDSTISAESFYDRIVALVDIVPPTTRYSIRSRVSKTCSAGNVVWIVTTSALLVGLPLALSLEDEAKIVAQEKEQQAGAQ Fusgr1 MVTLTEVEDEDTDSEISNE-SDETLAERLYALRDIVPPTTRSWISGKASTVSNSGKGAWVITTSALFFGVPFALSFAEDQQLTAMEQERQSGSD Galma1 MVKV-EIVEESSSVSLSSVESEESFIDRVVALKDIVPPTTRHNIVTRISKAASIGNIVWVVTTSALLVGLPLALVVEDEAKAVAQEKEQHQGTQ Ganpr1 MVNLTELSQAETDEEIDDDDDNESLSARLLALLDIVPPTTRASISSAVSKTSSAGKAAWVVATAGVMLLLPVILEVEKEQAALSQGGAGGVSQQ Gloin1 MVKLEEVIEGSTDDSDSED--EESILERVLALRDIIPEDTRESISNKISTIMSIGNGAWILTTSALLIFMPLAYEIEREQAYSQMENDGQGGNP Hisca1 MVKLQEVEDEESDDDDDDFTD--------------------------------------------------MSLSCAGD--------------- Klula1 MVELTELTEEDEEEFSSDDEDDENIYERLIALKDIIPPQKRKTISFLYNGTVSSGNLLWAVTTSALLLGVPLSLSILAEQQLIEMEKSQKDAND Lacbi2 MVKV-EIVDESSSASISSVESDESFFDRVAALVDIVPPTTRHSIASRVSKTASVGNIVWVVTTSALLVALPLALTLEDEAKIVAQEKEQQQGAQ Lenti61 MVKV-EIVEESSSVSLSSVGSEESFYERIVALADIIPPTTRHSISSKLGKTASVGNLVWIVTTSALLIGLPLALVLEDEAKIVQQEKEQQQGAQ Malgl1 MVRIEEVQDEEATDADSDEDDNESFWERISALKDMLSPGLRAKISRTWQLTSAAGKLIWIGVTSALLVGLPFALAVEDESRFAVQEKEQQQGSS Mellp23 ---------------------DETIIDRIYALKDIISPSSRTTICESWNKLSNLGNVAWVITTSMILVGLPMALSIEGESMLVAHEKEQAHGQQ Mnele ---------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------- Morel2 MVKLEEVSLD-SSVYSSDEDEIESILDRVWALQDVIPAKTRKSIADKCSTVYGLGNSAWVLTTSALLLVLPLMIELEHEQGLIEYEK-QQQST- Mucci2 MVKLEEVSAD-YSDFSDDE--DESLLDRITALKDIIPLKHRNRLSNSVSTLSSVGKSAWVITTSMFLLVLPLALEIEKEQALVAYEKEQQQGTQ Mydma ---------------------------------------------------------------------------------------------- Neucr2 MVQLTEVEDEDTDSEISVD-SQETFTDRLYALRDMVSPTTRGWFYHKYSTTTNAGRAAWAVSVSGLLIGVPFAIAFAEDQNYAAMEQERELGSD Orpsp11 MAYLEEVDEKTSSEEETDIEDDEELLSRIIALKDIVPPETRARISNTASSLFSIGNSAWILVTAASILALPVVLEIEREQAAIHQENQQQQLRQ Pench1 MVKLTEVEDEDTDSEISDD-EAESLYERVTALKDMVPPSARRTVYSTVSSITDSGKALWVISTSAFLLGVPFALAYAEEEQYIQMEREIKGANE Phybl2 MVKLEEVSND-YSDYSDDEDDDESLLDRIAALKEIIPLKHRQRMSSSVSTVTSVGKSAWVLTTSMLLLVLPLALEIEKEQALVAYEKEQQQGTQ Picst3 ---------------------------------------------------------------------------------------------- Plicr1 MVKV-EIVEESSSSSLSSVSTDETFIDRLTALVDIVPPTTRQSIYSRVSKTASAGNIVWVLTTSAILVGLPLALSLEDEAKIVQQEQEQQQGAQ Polpo ---------------------------------------------------------------------------------------------- Pucgr2 MVKIEELKLDESDGSSTSDPSDETIVDRIYALRDIIRPTTRESICERWNSIWELGNLAWVLTTSIILVGLPMALSIEAESMLVSHEKEQRQGQH Punst1 MVKV-EIVDEASSLSLSSTASDESLLDRLAALVDIVPPATRHSISSKLSATGSVGNVVWVVTTSLLLVGLPLALSLEDEAMRTAQEKEQQQGAQ Rhior3 MVKLEEVSAE-YSDFSDDED-DESLLDRITALKDIIPLKHRNRISSSVSTLTSVGKSAWVITTSMFLLVLPLALEIEKEQALVAYEKEQQQGTQ Rhoto1 MVRVTEVSDDDLDSVISDSDLQETIAERIAALKDIVSPSTRAAISDAASSTKGAGNAAWIVTTSALLVGLPLLLSIEGEAAIVQQEKEQPGANP Rozal11 ---------------------------------------------------------------------------------------------- Sacce1 MVELTEIKDD-EDDSDSDFEDNETLLDRIVALKDIVPPGKRQTISNFFGFTSSSGNLAWTLTTTALLLGVPLSLSILAEQQLIEMEKTQSDANN Salro ---------------------------------------------------------------------------------------------- Schco3 MVQV-EIVDEDSDDDLESVTSDETLLDRIAALKDIVPPSTRLAVANNVSKAGSVGNIVWVLTTSALLIALPLGLALEDEAKLVAQEKEQQQGTQ Schpo1 MVKLEEVVDEEKDQYIYAQEDEETIIDRIAALKEIVPVTWRVKIADGAKTATTGGKSMWVISTSALLLGVPFMMSLEEEAQLTEYEKQQRGANE Sorma MVQLTEVEDEDTDSEISVD-SQETFTDRLYALRDMVSPTTRGWFYHKYYTTTNAGRAAWAVSVSGLLIGVPFAIAFAEDQNYAAMEQERELGSD Sphar MAKIVDVTDG-----------SESLLDRLSGLVEFIPKPIRDTVYKVGTTTHSLGTVAWIGTTTFFVLGLPLMLAVEGEQQLESMELEQMQQQR Spipu1 MVELTEVHTEEDED---GDELDESLLERISALVDVVPPSTRRSIVRSVKNVTSVGSAAWVLATAAMLVGLPVALELEREQFVFQQEAQQQQQAQ Sporo1 ---------------------------------------------------------------------------------------------- Stehi1 MVKV-EIVEDSSSVSISTVDSDESILDRLTALVDIVPPTTRHNVVSKISSTARAGNLIWIVTTSALLVGLPLALSLEDEAKVVAQEKEQQQGQQ Tapde11 ---------------------------------------------------------------------------------------------- Thetr ---------------------------------------------------------------------------------------------- Treme1 ----------ETTSSVSSLSDNETIYDRLIALKDIVPPSTRISVYTKYEKSKGVGTLGWVISTSALLIGLPLALAIEDEGRIVQQEREQTAGQQ Trire2 MVTLTEVEDEDTESEISNE-SEETLAERLYALRDIIPPTTRGWVSSRVNAVAGGGKSAWVITTSALFLGVPFALSFAEDQQLTAMEQERQTGSE Umbra1 MVKLEEVSPD-YSDYSDSEL-EESILDRIAALKDIIPQKQRDRLSSGFTTISSVGKSAWVITTSMLLLVLPLALEIEKEQALVAYEKEQQQGA- Ustma22 MVRLEEVPDEEEEDESDAESDEETVWERISALRDIIPPSTRRSIASTFNTTTSAGKLVWVVTTSALLVGLPFALAVEDESRIVAQEKEQQQGAQ Walse1 MVQIQELKSEEIEEELDVEDEDESLADRISALKDIIPLETRNSIKEKFTNSVALGNLIWIVTTSSLLVGLPLALAIEDESRISMEEKSQQSGQQ Zygro1 MVELTDITDESDDEYGSDFEDNETIADRLVALKDIIPPKQRQNISSLFNTASSSGNVAWTVTTSALLLGVPLSLSILGEQQLIEMEKSQKDAND [Cluster2917.fasta_al_trimmed; alignment length = 207] Allma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ED-LLDDADREHIENMPEMERETLLFERSQEMQKYQERKVLRERRKQRAKKAELDDFN-KIKVGRSFVAKFCFYPEFNQRVQGCYGRVNIGGQAMYRMVKIKPYNMTNQYFGVTQGKDFFSDGPILQPEYERIN-KPSLNNKAKDLTNFVSLTDQIVRNRMQFNEKTVLRDKDTNNEKDIAKYQLKNLETSKNRKVNDKIRHVENVK Aspfu1 AE-LLSAKDKEEIMALPEIQREQILSERAQEVDRRNQDLALRRLKRQREKKADLRDIQ-RARVGRTNFAQVCFYPGFDEAISGCYARVNIGGINEYRLCLIRPYAMTNQYAVLAHGKAACSDSPFTEAEFNRCK-MATLAKKVADINRLINELNEKLRKQGSLDKRLETEKQAAGDDEEVSRLELAELMNLRNQKLNESVRRAQLEE Aurde31 DE-LLDESDRAKLLDLPEIEREEILAQRQEEMQRWRDRQALDKLKAERKAKVGIADLR-KIQVTRSMIGKYIERPWFEKLIAGAWVRIMVGGENVYRICEAKPYSVVIESVELKHGQARVSNVPFTDKEFDRVK-LPSIERKQAEIKRLTSDIDYQLKRKAQIDEYAHLLKRQRKDREETKNLALREFENKRNKLANENVRRAEAAE Batde5 SE-ILDADDRKRLMMLSELEREMVLADRQKKLDALRERTILRRRLRQKRESANIEDIR-SIVVTRDELERWVHADFFSSTIIGCFVRIGVGREQVYRLARVRVYRLTKIALKIAHGKAIVSNRPFTVSEWNRQS-MITVRRKKRDLQSAREEINTMIKRKKTLIEKLRIKQAEKGDQAQVD-IELNQLGNERNRKSNTEGREAEKNL Botbo1 DE-LLDEYDRQTLLELPEIEREGILSTRLEERQRLMDKLNLDRLAESRRERTSCADLE-KIRLTRDTLAKFCMAPWFEDLVKEAWVRYLVGGQPVYRICEVRPYKVVNQTLDLRHGTAKVSNSPFTEREFARHK-LPSVEKKHAQITKLANDISAIITRKNQLQEKSRLHQAGRQEFDEVANIQIQELENERNRKANEAMRIAS--E Botci1 -------------------------------------------------------------------------------------------------------------------------------------------MQKCAEINALVNELQTKLKKSSVLTERARLNNASLGNTELEEKYELEALENRTNRRKNEEVRQAQINE Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 DD-LLDEADREALDNMDEMEREQILFERMQEMDKYRERKYLQERRKQRAQHAKLEDIN-RIKVGRTILTQYCFHSGFEDTIVDTFGKINLGRQPIYRMVKIRAYKLFDIFLTVSQNKDIFSDSPINQDEFDREM-IEFVNSKFDELTKFYSDINDMIARKQKIQRKTNLLDRQQGNLEKVQEIKLKDIDNERNRKLNTNIRKAEIKF Cangl ED-LLDTADRDHLESLPEMERETILFERSQVMRKYQERKLFRERKKQRERKAEVQDFN-KIRIGRSFVAKYCFYPGFNELIQGCYGRVNVGGNAAYRMVKIKPYNMTNQYFGVTQGKDFFSDGPFVEQEFERIP-KPSIKTKFKEISEFISLTDEIVRNRMVLNEKTILKDKENGNEHDIAKYQLRNFETSKNRKLNNRIRNAESIK Capow AE-LLDAADRERLFALSEVDREAVLFERSEKIQALKERQIIRQQKKKDKSSLTLDDLN-RARLTRSKLEKYVHAPFFAKSIRNCYVRVNIGGQTTYRLAKVKAYQLTNKLIELDYCGSYVSNTDFTESEFYKIP-LPSLRHRSKQIQSMSQVIDAMLQERNRFQEISVLEQQLPGLREKLAETAAEENNNAKNRHKNSDLGRGEKVV Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 DE-LFDEADKRQIMGMSQLEREEILGQRAEEMSNANFKAELARRKREREQRATLRDFE-SVRVGRGFFSEVCFHPGFEEALTGAFGRVGVGRRTLYKMAQIKPYVFTDQYVIAQHGSVFMSNQRFTESDLDISK-VPSLKRKYDDLKALQNDISARIAKS--------------------KKYLLQRSSNRKNRILEERVRKAQLEQ Coere1 ND-ILGQKDRRWLASLTEIERERILAERQEKRDLLNEQRELRMKKRTRERRASLSEIN-TICLSRNQLEQWLFRPFLAEAIIGCLVRIVTREYNQYKMMEVPPYHLTDKYLTLRFGAATISNSSIKPEEHSAVRGYISVQKKLKDLDRARNEVSQMIAERNRLRERSQLNQLQNSDWEQLKKIRLEELDSHRSLLAPTSSRIPEIKG Conco1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 DE-LLDEADRERLLEMTEIEREEILASRMEQLQRKQDSKNLDALKAKRRAKITRYDLM-AIRVSRDMLARHCLAPWFEDYVKGAWVRYLIGGQPVYRICEIKPYKIIDRAIELKHGKSKVSNSDFPEKEWDRVA-MPTIEKKKEQMARLVSDITAMLARKNQLSERSRLNQARRQDAVEVAEIKLAALPNERNRKANEAVRKAELLE Copci DQ-LLDEEDKQRLLAMPEIKREEILAERIEEKQRLQEKQVLAQMKAKRRAKASLQDFN-DCRLSRDMVAKWCLCPWFDEYVKNSWVRYLIGSEPVYRMCEIKPYKVINQAVELKHGQSRISNSDFTQREFDRVT-LPTLQDKTAQMKKLQDDITFMLKRKKELQERSRLSQAKRLDHKEAAELKIAALENERNRRANESVRRAELAE Croqu1 DE-LLDVADKKRIQSLSELEREAILGERQDELQKIRDRENVKNMKMKRQEKATIDDIR-SVMLTRKRAVELCFTTFFQEYVKGMWVRVSVGREIKYRVGEVKYYEVTKVELQVVIAKSRISNSPFQENEWAFVA-IPTISRKLKNLENHRDVITKQVRAKKEMRERLRLQSEAKGETELYERLRLEQATNERNRRANEEIRRAEIAA CryneH991 NE-LLDEADREALENLPEIERENILASRLEEMQKFKDSQALDAMKNKRKAKPNRAELE-SARVSRYELVDMMHKDGFEDVITGAYVRIISPGRPKYRLYKIGSYSIESRALLVKYGSADVSNGVIEESEFQRVK-APKLKKKHDEIKALREEIDRRVDSRKSQEKIHQLMNTRRNDHVMVEKLDIIALGNENNKRKTEAMMRAHAAA Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 DD-LLDEEDRENLLSMDEIKREQTLFDRTQEMESYNEKKYLQQRRKQREQKAKLEDVN-RTRVGRSILLKHCFYSDFADTVIDCFARINIGKQPMYRMVQIKAYSTCDIYLTVNQNKEIFSDSPILPEEFDRED-ISYVNEKYESLQYLLNDVNEMIAKKQKLQQKTRVMDQQENNLSKVKELKLHKLDNERNRKLNLNIDRVESKS Dekbr2 DDELMDDDDREKLMAMDEVTREQILYDRMQEKEKKRERRYLALRKRQRERKATLSDFNQKVRSSRSLLDKYMYRDEFDTVIPGSYVRVSIGGRQQYRIAKVNPYKLCNTYLEVSQGNSYVSNSPFTQEEFEIID-IPSIEDKFGDLRAMSTDINKMVAKKQNLIRLAGLREEEKVELEKVKELQIEQITNQRNKKSNVLIRRAEQRR Dicdi EE-LFDDNDRYELSLLPEIDRENILSERYEKRKEARELWLQQKSQKKREKSLNINLMN-QCRLSRNMLVKWVDQPYFERYAPNFFVRVVIGNNPIYRIAEIKQYKVTDKLLVLSYAGSNVSNNAITPAEHEK---LPTIDMKIGDIKKAQDDIEKRASDRSKYLEKAKSIALPQ--SQEYRTIKIEELTNKKNKSLNSTTQTTEQVS Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba NA-LLDDRDRRD----RERERERDRYDDHDRRDRERDRRDRDRYRRGRARPLDLATVH-RLQVRRNELTEWCFRDDFPSLVQGGLIRVSVQIKVAYEISRISPYSVVHMALIVAGGRAYISNSRIEEGEFNAAS-LPALRRKADDMAEIRTELQRILERKAQLR--------QRNLQDEIRKLQLTNTSDQKRAEIEEEHREAQKLP Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 DD-LLSQKEKAEIMAMPELEREQIIADRMTEIERQRQNRLLRQMRQAKAEKAELRDYD-RVRLGRNEFAQVCFHPGFEQGIIGCYIRIALGGIEQYRMAVIRPYAITDQYVKAAHGKAAASSGKFTDSELNRVT-LPTLTDKVDDINRLINEIKTRLARISDLKERERIAKLQRGDDDRAEELELDNLGNRENRRLNEAVRKAQLKE Galma1 DQ-LLDEADKRELLAMTEFQREQILEERAGERQSMLNAKALANLKAKRKAKCTMADLE-GCRLTRDAIAKHCIKPWFQDYVSGGWVRYLIGGTPVYRICQVKPYKIINQAFELKHGKSKVSNAPFLEKEYDRVK-MPTLEKKVAQMGKLVSDITAMLARKNQLQERSSLNQKRRHDHAEVAEIMLAEDANERNRKANESVRKAEVFE Ganpr1 DF-LENDADRRELARLPEIERERILAERIEKRDDAQLRLETKRKKRPKKQRITYELIR-SVQVTREDLGKWDYYAHQENTISGGYVRVFIGKAAVYRMCCIEPYHITRHALKLAHAKALVSNSNISQEEFRRAE-WPSIERKAAQIASAREEFHEMIRNKQSLQEKARLWADDAGETERVEELELAQLENERNRKKEEQLKAAALME Gloin1 DE-ILDRNDRERLGNLNELARERILADRAEKKQHHLDLHAVQQLKRRRAEKITLQELR-TIQVSRHMLVNWMFAPFLADAIVGCYVRLHIGDKQVYRLCEINKYYVTNKVLKLRHADAIVSNQYVDQSEFERME-LPSTSRKQEDLNRAKEDVENIVQQKKALREKSNLTTLLRGDIKEAKELRIQEISNARNKKQNEDARAAEQRK Hisca1 AE-ILSAKDKAEVMALPEIQREELLSERAQQVDRHNQDLALRRLKRQREQKAELRDIQ-RARVGRSNFAQVCFYPGFDSAISNCYVRVVIGQQNEYRLCSIKPYAMTTQYAVLAHGKAACSDSPITEAEFNRCK-MATVANKVADINRLINELEEKLRRQGTNDERIQLEKRATGDEAAIAQCELQRFTNRRNQKLNENVRRAQLEE Klula1 DD-LLDEKDREKLELLPEMERESILFERSQQMQKYQERKLLRQHKKQRAKKSSLDDYN-KIQIGRSFVAKFCFYPHFNKIVEGCYGRVNIGGNSMYRMVKIKPYNMTNQYFGVTQGKDYFSDSPVTQPEYERIT-QPSLNNKSKAVNEFVCLMDDIVRNRMVFNEKQVLKEKQSGDIESESKYQLKALETSKNRKLNDRIRHAETIK Lacbi2 DQ-LLDEADRQRLLEMPETAREEILAERSEKKQRLNEQQKLADLKARRKAKSTLQHFE-SCRLSRDTLAKYCMAPWFQEYVRGAWVRYLIGGQPVYRMCEIKPYKVVNQVFDLKHGKSKVSNGPFLQKEFDRVK-LPTLEQKVAQLQKLISDISAMLQRRNQVQERSRLTQARRHDYDEVKDIQLAA-ANERNRKANEAVRRAEMAE Lenti61 DE-LLNEADRADLMSKPEIEREAILAARQEEMQRFKDKHQLESMKAKRKAKTTIEDLS-SCRLTRIDVSKHCMKPWFEEYVKGAWVRYLIGGQPVYRLCEVKPYKVVNQELELKHGESKISNGRFEPKEFERVK-LPSLEKKAAQMQRLATDIAAMLARKQAINERSRLQQERRQDYSEVKRIKLAELSNERNRKLNEQVRRAERME Malgl1 ---------------MNELEREDVLTERRDEISRRQQQAQLAAMRRKRAERPSLEQLN-SVRVGRDDLERLLFLPNGTDLVRGCFVKCSWGKEHVYRVHQIKYYDVMNSYVTFRWGGKPLSTQRITDSERQRAK-FPSFRSKQMQMESALSDIKKMLERKRELRHVTRLSSDAAGMPFSTAGSGVKHFDNERNRRLDERIQEAERRA Mellp23 NE-LLDLQDKLRIQSLSELEREATLGERQDELQKIRDRENVKNMKLKRQAKASLDDIR-SLTLTRTRAAELCCTDFFSDYVKGMWVRVSVGREVKYRVAEVKYYEVTTKTLQVVIANSRVSNSPIQENEWLFVP-IPTVSRKLNSITKYQDTITLQVRAKKAMRERLRLESEAKNDTELVERLLLQQASNERNRRANEEIRRAEIAA Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr NH-MMDEADKEYLASLSELKREEILLKRSEEYERAKTYWER---KQSAKT-ATFEELE-SIRVSRHKLFTWAHEPFFEKTVLGLVVRVSIGNVETYRMGIIRVYSLTDLHIRVRHGSDYVSNKPIAHSEYVRGS-LVMVKKKLEDLAHAKDDVAFIVASKKRVGEKERLQRELTGDKAEVDRLMVKQ--NERNRLDN---RRQERLA Morel2 DV-ILDAQDRADLMAMAEVDREQILFERAKKRTVLLDHRQVAKRLKKAQERATLDELN-SIRLGRDRLSKWCHSPFFKDTVIGCFVRLSLGRNHVFRIAEVKVYTITNLNLTLRHGNAFVSNGLFTEDEFRRVD-IPTVERKRKDIEHAKAEVQEILELKKQLKHRTILEQRNTEDSFEID--QLQALKNERNRTLNSTGREAEGRF Mucci2 DL-ILDEDDRRRLQALPEVERERILAERSEERQRNLERLEVRKLTRRREEKPNLEEIQ-SVSVSRSMIEKWIFAPFFENTVIGCFVRLYIGKVPVYRLCQIKTYKISNKALKVKHGKAIVSNQPVTQQEFTRVR-VPTIEQKAADLKQAKEEVNEMIEKKKAVKEKAQLLARAHNETEKVLKLELKELENSRNRNRDIEVHEAERRA Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 DE-LLDYEEKEQIMGMREIEREQILAERREENERIRQNRMLRQLRRAREERAELRDFE-RVRVGRSRFAEVAFYPGFDEALTGCFVRLNIGRQDVYRMALIKAYALVDMYVKAAHGKATCSDRKFTEAEYNRVP-FPDLVDKIDDINRLVQELSDKLKRQNALQQREYLKKQQANDEAAIARYRLEKLENMENRRRNEEVRKAQLRE Orpsp11 -----DEEDRKYLDNLPEIEREAIIAERAEKKQILKERLEVKRKLRRKREKITLEELN-SIRISRDELEKWVYTSFFNKTVIGGYARLGIGKNYIYRITKIRTYKIIKKALILEHGKAIISNSPFTEQEYNRQQ-LPSIKEKQQQIEEARN-------------------------------------------------------- Pench1 AE-LLSAQDKKDIMAMPEIQREETLSERAQQVDRHNQDLALRRLKRQREQKAELREIR-RAQIGRNNFAKVCFYPGFENAMIGCYARLSIGGQNEYRLGLIKPYALTDQYVKLAHGKATFSNSPLTEAEYRRCK-MATVESKVADINRLLNELNEKLRRQGAFDNRLELERNVNGNVEEAEKIELQKLANLRNQKLNENGRRAQLEE Phybl2 DL-ILDEEDKKRLSALPEVERERILSERSEERQRNLERLEVRKLTRKREEKPTLKELH-AICLKREMIERWLHTPFFEKTAIGCFVRLLIGKKLVYRLCQIKVYKVSNKAIKAKHGNAIVSNSLPEQHEYSRLP-GPTVQRKAKDVKHALDEVADMIARKRAVNEKAELLARSNNDVDKITQIMLQQLDNKRNRERDIEVHEAEMRQ Picst3 ----------------------------------------------------------------------------------------------------------------------IFSDSSISHEEFDRET-IDYVNDKYDQLQAFFNDVNEMISRKQKLQRKARLMDEQQANPQKAREIKLKKLDNERNRKLNTNIRKAEIKS Plicr1 DE-LLDEADRQRLMQMSEIEREETLAQRLEELQRIQDKRNLDDMKAKRKEKITIEDLN-SVRVTRDMLAKYAWAPWFEDYAKGAWVRYLIGGQPVYRICEIKPYKVVDQAFELKHGKSKVSNTPFDAKEFDRVK-LPTLEKKAAALHKLANDISAMLARKNLLNEKSRLNQARRQDWAEVAEIKLVELANERNRKANEAVRKAELAE Polpo EQ-LLNEEDRIKLSKLSQFEREDIIAERYEKRRELKERWDQQQK-------------------SR---------------------------------------EKKE-------SSS--------------------GDDRVGGSSRRQSD-----SKSSKALQK------QKKFEMEHDYIKEAEM------------------- Pucgr2 NE-LLDAADKQRIQSMSELDREAILGDRQDEIQKIRDRENVKNMKQRRQAKATLNDIR-SVMLTRSRAAELCSTKFFEEYAKGMWVRVSVGREVKYRVGEIKYYEVTKVALVVVLAKDVVSNSSIQENEWLFVR-LPSISRKIKMIEKYQDDITAQVKAKKEMRERLRLESEALGNLELAAQLQLEQASNERNRKANEEIRRAEVAA Punst1 DE-LLDEADRDHLLELTEMEREEILASRLEELQRIQDKRSLEALKAKRRAKLTRLDLA-ICRVTRDMIAKHCMAPWFEDWITGSWVRYLIGGLPIYRICEVKPYRVVNQSIELKHGKSKVSNADWNDREFDRVK-LPRLEKKHAQMKKLVEDLAKELAKRRALQEKSRLNAANRQDWDECASIELSALNNERNRRANEAVRKAEIAE Rhior3 DL-ILDEEDRKRLQALPEVERERILAERSEERQRNLERLEVRKLARRREEKPQLEEIQ-SACISRSMIEKWLFAPFFENLIIDGFVRIFIGKTSVYRLCQVKTYKICNKAIKLKHGKAIVSNQPVSQQEYSRIR-VPSINQKVEDIKNAREEVNEMIEKKRSVKEKAQLIARSNNEIDQVLKLELKELENSRNRERDIEAHEAELRA Rhoto1 AM-LLDEAERRRVAGLTELEREDFIATRKEEILEADNRRMIAEMKKSRTEKAELADLL-QIQVTRTKLAEMCRAPWFEEWIKGAFVRYSLGGQVRYSLCQVRSYRFTDLWLRLKHGKSAVSNSPIISHEWVRVP-ATTAKKIKEQLAKRTSDLAAEL-AKKNKQARVRLKMQQNGDIEKAAELQLAELENDRNRAANEEVKRAEARS Rozal11 QE-IRDEEDRKWLFSLPELQREEILFERADARK-----------LKKLKEKADQKDIE-SIFLTRSRLEKWMFRSFFEDVVKGCFVRVSFKKENVYRLAQIRVYKITDKALSLKYGNDILSNSFFTDKEYSKIK-PPTCVEKNQEIIEAKSEVSKMMQEKKRFNEKANLLAEYENDEEEIERIELSRLENRRNRLSNEEIREAERKS Sacce1 ED-LLDESDREHLESLPEMERETLLFERSQIMQKYQERKLFRARKKQRARKPEISDFN-KLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGGKTSYRMVRIKPYNMTNQYFGVTQGKDYFSDGLFAEDEYQRMI-KPSLSNKTKEVMDFVNTTDEVVRHRMQFNEKTVLREKETNNEKDIAKYQLRNFETSKNRKLNSNIRNAEHVK Salro AE-MMDEEDRKYLEGLTELERELELNRRNEEREKAKQRWEMEREAARRKSPATLEQLE-SIRATRTKLLEWCHEAHFPETAAGMMVRINLGGVSTYRLGQIRLYELTRFYVLVQHGRSFVSNGPILQKEFMKMA-FPTVSRKRAELEALKTDILYTIESKRKCEEIDGLRLEASKEEKE-QKLALRQEEDTIDRLERAERRRAEKLQ Schco3 DE-ILDEEDREHLLGLPELERENILAQRLEEKQQKLDKAGLMAMKAKRKEKVTLADMW-KIWLTRDMIVKHCYAPWFQDYAKGAWMRYLIGGMPVYRVCEVKPYAIIDFDVVLRHGDAKVSNSKPSDREFARLP-FPTIARKSEEMRRFVSEITYMTKRGRELKERARLEQAARRDFDEVDALQLAALANERNRRANEAIRKAELAE Schpo1 DE-LLDEADRAKIMAMTEIERESILFEREEEISKLMERRELAIRKKRRQERANLYDLN-AIRLGRKHVAEYMYHPIFESTVTGCFVRVKIGGQGVYRLCQVKPYRVTKVSLECFHGRSVLSNEPFSDHDFQRLS-MPSVQRKLNDLRDMSKEVSDIINRKKELSEKTRLRQRVAGNAELVKEIQLNTLENERNRRRNTEIRLAEQRM Sorma DE-LLDYEEKEQIMSMREIEREQILAERREENERIRQNRMLRQLRRAREERAELRDFE-RVRVGRSRFAEVAFYPGFDEALTGCFVRLNIGRQDVYRMALIKAYALVDMYVKAAHGKATCSDRKFTDAEFNRVP-FPDLIDKIDDINRLVQELSDKLKRQNALQQRDYIKKQQANDEAAIARYRLEKLENMENRRKNEEVRKAQLRE Sphar DS---DEKERQMVDAMTELQREVWIVERTDENEKKKARQKIERKQRRREEGVTVEHLN-SIKLSRHKVTKWHNLPEFPELVVGCFVRASIGGRSVYRAVEVKSYTLCNQLLTCAFGVNYVSDGLITDQEFSQKK-LPSIKAKTQQIEDMLNDIEYVLKQKKDQSEKIRMETEQEGDEKEVERILLDGLENERARVHNERAERAEARA Spipu1 EA-LLDDADRQRLTQMSELDREAILAERKSKFERMRERLEVKRMLRREREKPTFNEVV-SIQVTRSELVDWAFAPFFEKTVQGCFVRYGLGTRNVYRVCLIKTYPVVQKVALMSHAKAKVSNGRITEAEYQRAA-DIPIQRKRDDLQRAREEVARIVEQKKALNEITELRRRSTANSDEEAKLRLEHLLSKANKPETSRVRN----- Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 DE-LLDEYDREQLLQMPEMEREEVLAQRQEELQRIQDKRNLDQMKARRKAKITVLDLE-KIRLTRDALAKHCLSPWFEDYVKGAWVRYLIGNQPVYRICEIKPYKIIDQNLELKHGTAKVSNAVFTAREFERVK-LPLVEKKAMQIQKLTSDVSAVLLRKSQIQEKTRIIQMKRNDRAEVAVLQLEEILNERNRKANEAMRLAAQAD Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 NE-LLDEDDREQLEGLPEIERENILASRLEEIQKLKDAQQLDAIKNKRKATPDHRELN-SARLSRYEIVDMLYKDGFDELLKGSYVRIPAPGRQKYRVHKVGSYKIEDRGLLCQYGRVDVSNGDIDDGEFSRVA-PPKLLKKHEDIKAMHREISRQVAARRAANEISNLISSRRNDLPTVERLQIISMGNEHNRKRAEATLKQQEAE Trire2 LS-LFSEAEKAEIMAMREVEREQIIAERVSEIERQRQNRLLRQMRRARAEKPELRDFE-RVRLGRNEFAQVCSTPGFEAAITGCYIRIALGGIEQYRMALIRPYALTDQYVKAAHGKAAASGGSFTEAELNRVP-LPTLVNKIDDINALINEIKARLAKRNELRERQRLANLRRGDDQRVEELELEKLGNRENRRLNEAVRKAQLKE Umbra1 DY-ILDEEDKRRLLALPEVEREQILSERSEERQRNLERLEVRKLARRREEKPTLDEIN-AITLTRRMVESWIHTPFFEDTAVGCYVRLFIGKTPVYRLCEIKTYKVSNKAVKARHGKAIISNGAVTQQEYARGR-KPNIENKKESLKAAREEVADMIAKKRELNEKTMLHTKSDENHAEADRIQIADLENKKNREKDVEMKEAEKIA Ustma22 DE-LLSARDMEELMSMNELDREDILARRRDEINERRQKFELAALRKKRKEKPSLSDLN-AARVTRDQIESRLYAPRWRDVLTGSFIRFSWGTETVYRIHQVKFYDLCNVYLVFEHAGNMLSRGEFTESERERGK-LPKVSRKADELEKFFTDIGKMLETKKKLR-ISVMGGRTAG--FDSPRAPIGTKDNVRNRALDSKQSDVERKA Walse1 AD-LLNAADRANLMDLDELEREDILASRQEEMQKYKDSLNINKLRSKREAKIDTADIH-KVSISRTMLADFCYAPFFEDFVKGTFVRYLLGGKPDYRLCEVRPYAITNQQLVLKQGRAKVSNSRCTDREFDRAR-LPTIEMVRTQIEETRKDINFKLQKKAAVMEKAELQQRARRDVQEAEYLKLEAMEQQHSIKSKPKVRKLDKTK Zygro1 ED-LLDEADRDYLGGLPEMERETMLFERSQIMQKYQDRKMFRQRRKQREKKANVADFN-KAKIGRSFVANFCFYPGFNDIVRGNYGRVNVGGETLYRMVKIKPYNMTNQYFGVTQGKDYFSDGAITQQEFERIT-GPSLENKAKEINSFVSLTNDIVRNRMVFNEKTVLKEKETKNERDIAKYQLRSFETTKNRRVNDRLKNAEQVK [Cluster2918.fasta_al_trimmed; alignment length = 180] Allma1 KLSFKG--SK-KRKRKHGWVVLAHLT-GPCLVLFPDPSTLYHPPHVVARP--SYEPTDVHQVFVAAKLPGSSAWSLKTADKHGVVLCAVTAVGATEEWVAFQSVGQYLQIVRTDPQSQLRADAKDIGFCS-SFLVKVQAQARE----------------GKLAEALLDRRAKTKSDRYCK Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 PLTFKGD-KKRKHREIA-WVSADDIA-GPVVLVLPSPTCIASDAKVFASELETAEPHDVRQVWVATRVAGTESLSFKGCDTYGILSASASAISHYESFFALQTGEAFVCVREAS--GEVRGDASSLGFET-TLRVRMQARFK-PRIKISRKELKRARREGTFHEEVLDVRVKGKHDKFAW Aurde31 KLTFKGDKSK-KRKR-KRWVLPEELR-GPTFIFHPSPLCVSYDTKLALSALSECTPAQVSHVWVATRVAGAETVNFR------------------------------------------------------------------------------------------------------- Batde5 RLTFKGDNHKKSKKR-HGWVHCKDVM-GPVIIATSAPSLLYKNQNLSIAHLPTIEPVSAIQVFIANCL-PGSTTTFKSSDKYGVVTCDMEAAGPAEEWFAFQNMGLFLTAVA----ESVRADADSIGFKQ-VFTLKCQAAVKHAAAKLRRYQLINASKQGTINEELLNRRSKVKSDKFCK Botbo1 KLKFKGDK-K-KRKR-KAWVQPEQVL-GPTFLVHPAPTCIAYDSRITFPALSSLTPNEVSHVWVTTRVAGSLTINLRTCDAHGVVSADREARGPQEEWVAFQNVEKYLGIDEAG--GQLRGDAENIGFGE-RFWVKVQSEYK-KKAGNHKFQLKKARKEGRLTEAMLDRRAKLKSDRFC- Botci1 PLSFKGDKKKRKRVD---WVTAEDVV-GPVVFVLPSPSCIACDTKVFASALETAEPHDVRQVWVANKVAGTETYSFKGCDKFGILSANTEAVSPLESFFQIQTLDTFLTIK-EN--AEIRGDADSINFNT-TIRIRMQARFK-PKLKISRKELKRARKEGDYHEALLLIKVKNKHDKYS- Caeel GLKLKAGKKEKKKK---GWRKIADMKGGT-------NVAIEVASRTYVAAMDEGEGPNPEEIFALVKTPDDSKISLKT-DSEYQLVAMAEAIGSREQFTAFQAVPLFLSTVP----KHIYVASRTATENE-MVNIRTDAIQE-GPVDVKMYQVKKAQADGSAHELLLDRRMKMKSDRYC- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow KLKLKGIDKKNKSASSSKWWAVPNLR-GDVLI----KYILAADNSLTTGPLYDPEAPSPAEIFTV--VQPEPNVAFRSATTEGQAVAQTKAVGPREIWFGIQSLNKFLSATP----GAIFANSEELGPSE-RFFLRSNRPRRETRLDSRKYQLKKARLDGTVHEALLDRRAQLKGDKYCK Catan2 KLTFKGDPSK-KKKRSHGWARASHLE-GPLVILFPGPSSLYNPTHAIMRPLDAYEPTDVHSVFVIHKLVGSSSWSIKSAEKSGAVTCGSEAAGPKEEWVAFQSVGGYLSVKDLEKRAVLRCDKQDVGFCE-QFCAKVQAEVVHEYRKVKKFQLFKAKKEGKLAETLLDRRSKTKSDRYCK Cioin KLVFKGEKKEKKKKHKKGWWKTSEFK-G--------TIAIEM--HTYISAMDEGDGPDLPEQLTCVVI-SDSKVAFKT-DRNNKVVGISDAISSKEQWLALMA-GCFINCND----G-IVATSRSAGSEE-LVQVRSISERK-SNEDVRKFQLDSAKEGGKLHEELLNRRAKMKSDRYCM CocheC53 HYVVDSD-------------CADDIS-GPVLIVLPTPACLACDAKVFASDLETAEPHDVRQVFVATRVAGTEQLSLKGCDKFGVLSATATAISPEETFFSLQTADKFVSARDAG--PELRGDTEHIDFTT-TLRIRMQARFK-PRLKISRKELRRARAQGNFYETALDMKVKSSHDKYAS Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conco1 KLSFKGDKKKKKKSSSEGWTFAEDLI-GPITISFPSPVTFQTNE---MSILKNFEPNTVAQVFTGQRIIDSTKFNFKTCDKFGVVTAHKEAIGPQEEWVCFQSIDKFLTFDE-----KLKATDDYIGFNQ-TFKVRCQNEVRFNRRQGQKYVLRRAKDEGKLNEALLDRRSKVKSDKFCM Conpu1 KLKFKGEKKK-KRKR-DTWVLPEEIR-GPTFIMHPSPVSVNFDSRIILHSLDQRTPTEVAQVWVTTRVAGSSTINLRTCDKHGIVSADREARGPEEEWVAFMNVEKYISIDEAG--GTLRGDSEEVGFKE-RFWVKIQSKYK-KEAHNRTYQLKKARKEGRLSEALLDRRAKLKSDRFC- Copci KLKFKGEKHK-KRKR-RTWVLPEEIR-GPTFIMHPSPISINFNAKVVLHSLDDRTPTDVAQVWVVTRIAGSTTVNLRTCDKHGLVSADRDARGPQEEWVAFMNVEKYLSVDEAG--GALRGDSEEVGFRE-RFWVKIQYKYK-KEAHNKLYQLKRAKKEGRLAEAMLDRRAKLK--RYVC Croqu1 KLMFKGEKKKHKKRR-HGWLNPPHIL-GPLYP----PNPVTPIASEALETL---EPDDVNHVMVCTRIVDSDTVTLRVTDELGEVTAEREARGVQEEWFAIRSVNKYVSVEEAG--GAIRCDSVTSADSSCQFLIRMQATEL-IKAKI---QLKKARKEGRLAEELLDRRAKLKSDRYAK CryneH991 KLKFKGEKKKKKRSHHHGWMFPSEIN-GPAYILLPTLTCLAWDAKVYAAPVDTIEPTDVNHVWVISRLSGSEDVSLRTASPSGSLTATTPSRGPLEAFFALQIQSKYFSATTAG---ELRADADDVGEFE-GLRIKCQREFV-YKARNREAQVKKAKKEGRYAEAMLDRRAALKSDRYAK Crypa2 PLSFKGDKKKRKR-E---WVSADDVS-GPVLFVLPTVTALACDAKVFTLPVETAEPHDVRMVWVANRIAGTENHRFKGCDKYGILTATTEAISPLESFFQVQTLDTYLTVQ-AN--AEVRGDATEMNFDT-TLRIRMQARFK-PRLRISRKELKKARREGDYHERLLDLKVKNKHDKYG- Debha1 KLTFKGDKKKRKRTENEGWSTASDLK-GPCIVLGDSHVVLQVGEEVVADTVNKCEPNKVNQVLTLSRLDTSKTFALKTIFTFKKVDIANDTLGCDEPWLVLEPSVKFVETGKSEIDG--------------RFVIRVQSKNTLKGSRYKETNLKDAISTGDINEQVIQEKSKSKW----- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel KLVLKGEKKKRKK----GWWAAKDIT-G--------TVSIEF--RSYLKAMDAGDGPDPEEIFTAFPI-NDRKVAFKS-EKDGMVTGRSEAVGGMEQWMALLS-GHFMSIDP----D-CVALRKKVGQHE-ICKVRSNASRD-VVIDVKKFQLEQAKAQGSLHETLLDRRSKMKADRYCK Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba RLRFKGDKRKAKDRE--GWVPAEDLG-GPIYLVHYRRLCLAVDEIVLKRAIPSDEPDDVSKVFVASMSPGT--VLLKSADTFSGVAADADAAGSLQEWLVLRGGARCLAVDSAG---DLRAALDDVLFRP-YVQAPRRAALR-RRARLRKSQLRKAQKAGRLAEALLDRRSKAKSDRFCM Fomme1 KLRFKGDKKK-KRKHVETWVRPEEIR-GPVFIMHPSPVCISFDSRAVISSLDSREPTDVSQVWVATRVAGSDTLTLRTCDDHGIVSAFREARGPQESWIAFQNIEKYLGIDEAG--GSLRGDAEEIGFNE-RFWVKVQSRYK-REASNRTYQLKKARKEGKLAEALLDRRAKLKSDRFC- Fusgr1 PLTFKGDKKKRKR-T---WVSAEDVS-GPIMIVLPTPSALACDAKVFTVPIETAEPHDVRQVWIVNRVAGTESFRFKGCDKIGMLSADSEAVSPLESFFQIQTLDTFLSIKNAS--SDVRGDADTISFDT-TFRIRMQARFK-PKLRISRRELKRARREGDYHERLLEIKVKIR------ Galma1 KLKFKGEKKK-KRKR-ETWVLPEELR-GPTFVVHPSAISINYNSRIALQAIDDRTPTDVSQVWVTTRIAGSSTINLRTCDAHGLVSADRDARGPQEEWVAFMNVEKYLGVDEAG--GQLRGDSEEVGFAE-RFWVKIQYKYK-KEAHNHLHQLKQARKEGRLAEAMLDRRAKLKSDRFC- Ganpr1 RLRFKGEPKKKKKKR-KGWINADDIA-GPLFFVTTVPSSLCTFEVVSITPAVALEPSSVTQVFVAKRANPSVPFSLKSCDKFGLVTCEQEAVGPLEEWVAIKHHDKFLKADSTGPRSVVRADSENVGFAE-VWRVRCQAETR-AAVRIKKFHLKRALKQGKLHEALLDRRTKLKHDKFC- Gloin1 KLSFKGDRKKKKKKR-KGWVFAEDLI-GPLFLIFNSLSCLYCSESIGVQPLPTIEPEDIASVFIGSRIVGSTDISIKTSDKFGVITAEREAIGPQEEWIALQSIEKYLSVDEAD--GNLRADVETVGFCE-TWKIKCQARLR-KKVKIKKYQLKKAKKEGNFAEALLDRREKVKADRYCK Hisca1 PLSFKGDKKKRKRH----WLSADDIL-GPVVIVLPSPTCIACDGKVFAQEIETAEPHDVRQVWVATRVAGAEGINFKGCDKYGILSANAPAVSACESFFSFQVAEAFLSIKEAS--AEIRGDASSISFNT-TCRVRMQARFK-PKLKISRKELKKARKEGSYHEAILNARVKGKHDKFAS Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 KLKFKGEKKK-KRKR-DTWVLPNEIR-GPTFITHPSPISVNFNSRIVIQSLDDRIPTDVAQVWVTTRVSGSPTINLRTSDAHGLVSADRDARGPQEEWVAFMNVEKYLSVDEAG--GQLRADSEDVGFAE-RFWVKIQYKYQ-KEANNQLFQLKRARKEGRLAEAMLDRRSKLKSDRFC- Lenti61 KLKFKGEKKK-KRKH-ETWVLPEEIR-GPTFILHPSPICVTYDSRIVLHSVDERTPTEVSQVWVVTRVAGSPTINIRTCDKHGLVSADREARGPQEEWVAFQNVEKYLSVDEAG--GSLRGDSEEVGFGE-RFWVKIQNKYK-KEAHNKLYQLKRAKKEGRLAEALLDRRAKLKSDRFC- Malgl1 RLTFKGDK-KRKRSKIQAWVSPGEIT-GPCFVHQRQV--LSFNAQVETSTVE---PLTVHQVWVATNLP---EWTFKSSSSYGAVIASNEARGPQEEWFALQSKGGWLATEDSS--SLVRADAKELTPAC-VWDVSVQWRFR-HAYRARSRQLLRAQREGRLAEAMLDRRSKLKSDKYTK Mellp23 KLMFKGEKKKHKKRR-HGWLNPPHIL-GPIYS----PSPVTPIATEALETL---EPDDVNHVMVCTRIVDSETVTLRVTDELGDVTAEREARGIQEEWFSIRSINKYISIEEAG--GSIRCDSTTSDDPSCQFLVRMQAAEL-IKAKIRQSQLKKARKDGRLAEELLDRRSKLKSDRYAK Mnele ------------------------------------------------MACEQHEGPENAEIFTALPGSAADKLAIKT-ALDGSISGRSEAIGTREEFQVLKG-GRYVTFNT----G-IGCTSEEIKENN-KVLVRTRGDKE-RKVEVKMYQLKAARKEGRFHEEMLDRREKMKSDRYCM Monbr -MTARFGAHW-------AWWQVAEFT-G--------NLLLEC--RSYVMAIDERDGPVAQEVFTIIKV-SDARIAIKTDNDDGVVYARAEAIGALQLFVSLRG-KKFLSILP----R-CTCNKNQMDLGT-TFQAFSCAERK-EKKKAMRFQLGSARRQGRLHESLLDRRAKVKADRYCK Morel2 KLSFKGETTK-KKKR-KGWVPVRDLG-GPLFLTFASPSCLTIDDVNMATLQPTAEPTAVHQVLVAT-MIPDSDLTLKASDKFGIVTAHTEAIGMQEEWIAFQNHGKFLSVDEAG--GQIRADSETIGFCE-IFRAKIQARFR-KKAKSRKFQLNKAKKEGRFSEALLDRREKLKSDRYCK Mucci2 ----------------------------------------------------------MQQVFVGSRITGSTNFTFKSSDKFGVVACDSEAIGGQEEWIAFESVGKFLMVDEAG--GRIRADAEDVGFCE-SFRVYCQSRFK-YKPKVKKYQLKKARTDGRLAEALLDRREKMKADRYCK Mydma KLKLKGFSKNSKRK---GWWPITKLTGG--------NVAIQC--SANLFAVDSDDGPVQEEIFTMIRL-SDNKVGFKS-NARGDVLARSDAVGPQEQLVALQG-GYFLTFTD----G-VKSLSRVAKEKE-IIFLRTNASRN-KKK-VKQFQLEKARNVGKLHEAMLDRREKMKSDRYCK Neucr2 PLTFKGDKKKRKR-T---WVSADDVS-GPIMFVLPTPTALACDVKVFTLPIETAEPHDVRQVWVANKIVGTENHRFKGCDKIGLFTANSDAITSLESFFQIQTLDTFLTVR-AN--AEVRGDATEISFDS-TLRIRMQARFK-PRIKISRRELKRARREGNYHEVMLDLKVKGKHDKYG- Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 PLTFKGD-KKRKTR----WVSADDIA-GPVVIVLPSATCVASDAQVFASKLETAEPHDVRQVWVASRVAGTESFSFKGSDTHGIFSATASAVSHYESFFSLQTHESFLSIKEAS--GEIRGDANTISFET-TVRVRMQARFK-PKLRISKKELRKGRREGNFHEVLLDVKVSGKHDKWA- Phybl2 KLLFKGDKQK-KKKR-KGWVRADDLV-GPLFFTHPSPICFTVDDLLA-YPLPHPEPLIVNQVLVGSRLLGTSNFTFKSSDKFGVVECNREAIGGTEEWFAFKNAGKFLMIDEAG--GKIRADSEEVGFCE-TFRVYCQARFK-RKNKVKKYQLKRAKQDGRFAEALLDRREKVKADRYCK Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 KLKFKGEKKK-KRKR-ETWVLPDQIR-GPTFVMHPSPICINFDSRIVLHSLDDRTPTDVSQVWVTTRVAGSPTVNLRTCDAHGLVSADREARGPQEEWVAFMNVEKYLSVDEAG--GQLRGDSEEVGFGE-RFWVKIQNKYK-REANNKIYQLKKARKEGRLAEALLDRRAKLKSDRFC- Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 KLMFKGEKKKHKKRR-RGWLNPPHIL-GPLYM----PSPVTPIAASALASL---EPDEVNHVMVCTRVIDSDDVTLRTADQLGAVSAEQEARGAQEEWFALKSCNKYLTVEEAS--GDIRCDSDSPADDCSHILVRMQAGEL-VKAKIRQYQLKKARKEGRLAEELLDRRSKLKSDRYAK Punst1 KLKFKGDKKK-KRKR-DTWVMPEEIR-GPTFIFQPSPVCITYDARIILNALDERIPSEVSQVWVTTRVAGSPTINLRTCDKHGIVNADSDARGPQEEWVAFMNVEKYLSVDEAG--GQLRGDSEEVGFRE-RFWVKIQNKYK-KEATNRIYQLKKAKKEGRLAEALLDRRAKLKSDRFC- Rhior3 IFFFV------------VWVPADDLV-GPLFITQPTPVCLTTDEFMP-YPLP-PEPTIMQQVFVGSRVVGSTNFAFKSSDKFGVVECHSEAIGGQEEWFAFESVGKFLMIDEAG--GRIRADADDAGFCE-TFRVFCQSRFK-YKPKVKKYQAKKAKVEGRLAEALLDQRSKSKADRYC- Rhoto1 GLHFKGEKKKTKSKS-RGWIPAPLLL-GPSYLTLPAPSAGTESSAAQLASLDHSEPSDVNHVWVCARIPDTNDVTFRSCDEYGRVSAEREARGMQEEWMVIKS-GKYLSVDIAG--GELRGDEEKESSTE-RWRLMMQGEYV-VKAKIKKYHLKKARKEGKLAEAMLDRRAKLKSDRYC- Rozal11 ----------------------------------------NHNE-----------------------------FSFKTSDKYGIVEARAEAIGLQEEWWAIMNADKFLSFDA-----EIRCDSEHVGFNE-TFQIQMQSRYRFEKRELRRYHIKAAKLKGNLHEVLLDRRSREKTD---- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro ALKFKGGKHKKKKK---AWWQVKDLT-G--------NVIMES--GKYVIALDNSEGPDVQEILTIMCV-SDNRVAIKTESESGDVTGLKEAIGALELWVLFQG-KKVLEVAP----E-AKCSSAVGEGNT-HFKLWSCAERK-KEKKARRFQLKRAKQEGKLHEALLDRRAKMKSDRYCM Schco3 KLKFKGEKKK-KRKR-DAWVRPDEIR-GPTFIYHPSPICITYNARLALAPLAERTPTDVSQVWVTTRVAGSPTINLRTCDAHGIVAADRDARGPQEEWVAFQNVEKYLSIDEAG--GQLRGDSEEVGFNE-RFWVKIQNKYK-QEAHNKLYQLKKAKKEGRLAEALLDLRSKLRSDRFC- Schpo1 RLTFKGDKQKKKKKNTKFWTDANELE-GPAVIYKIDGVSLGIEESCVLLPLDSLEPELTRQVFLLSILNNT--ILLKSCSKSGDLYCTQEAVGSQEQWWAWKSVKKYLTLSR-----AIACVSDTVIPEA-KWRIRVQTRFL-KKNKIHSRQLKKAFKEGVLHEALLDLRVSSRSDKYG- Sorma PLSFKGDKKKRKR-----WVSADDVS-GPIMFVLPTPSALACDAKVFTLPFDTAEPHDVRQVWVANKIVGTENYRFKGCDKIGIFSALSDAITPLESFFQIQTLETFLTVR-SN--PEVRGDATDISFDT-TLRIRMQARFK-PRIKISRRELKRARREGDYHEVMLDLKVKGKHDKYG- Sphar ------------------------------------------------------------------------------HEHAG---------------LT------------------VGCYTKDSEESN-ELIAWCGAERK-VKKAAKKNQLKDARKKGTLNEALLNRRSKVKADRYCK Spipu1 KLSFKGDNKKKKKKR-KGWVAVDDIK-GPILLLTTSASVLNCSDKVQFTPIDSYEPTTVSQVFVAKRL-PDSSLCFRSSDKFGVVQCEREAMGPSEEWLALQSSEKFLKCD-----ARARADSENVGFKE-VFQMRCQAANK-ARAKIKKFHLRKAKKEGNLNETLLDRRSKLKSDKFCK Sporo1 GLKFKGDKKKKRSKL-SGWVVAPLLL-GPSYITLPSPTVSTSTSAAALAQLDENEPRDVYHVWVCTRIPDTNDVTLRSADELGQVTADREARGPQEEWFTLKS-GKYLGVDEAG--GELRCDGTEPGQTE-TWKITMQGEFV-AKAKILRYQLKRARKEGKLSEAMLDRRTKLKSDRYC- Stehi1 KLKFKGDKKK-KRKR-ETWVRPDQIR-GPTFIFHPSPVCINFDMRIALPSMDERVPTEVSQVWVTTRVAGSLTVNLRTCDKHGLVSAYREARGPEEEWVAFQNVEKYLSVDEAG--GQLRGDSENVGFGE-RFYVKIQSKYK-KEANNKLYQLKRARKEGRLAETLLDRRSKLK------ Tapde11 RLAFKGEAKKKKLSRPAGWTDAEDLQ-GPIMIAYAFAVSLVADASVFTIPLEDAEPHDVRQVFVASRPAGVVSLK-NGTDRFGDIRCEKDAISPSEEWWSIQSSETFVSISQ-----AVRADVQEIGFCE-TFRIRMQAQNK-SR-KLSRKELRHAQKSGELGEAILDIRVKGRSDKFG- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 KLKFKGEKKKKKRTHHEGWVFPEEIS-GPSFILLPSLTCLAWDPKVYAAPIDAVEPTDVNHVWVISRLSGSEGISLRSATPSGTLTANTPSRGPLEAFLSLQ-TEKYISVSSSGLGKELRGDA-DTPEDA-QLHIKCQREFV-LKAKNRDYQLKKAREEGRLAEAMLDRRAAMKSDRYAK Trire2 ------------------------------MIVLPTPSALACDAKVFALPIESAEPHDVRQVWVANRVAGTEHFRFKGCDKIGQLSATSEAVSPLESFFQIQTLDTFLTIK-PN--AEVRGDADAITFNT-TLRIRMQARFK-PRIRISRRELKRAKREGDFHERLLEIKVKSKHDKFG- Umbra1 KLTFKGDKHKRKKKR-KGWVLCDDLI-GPLFITHPSPICFTVNDLVP-YPIPSPAPTITNQVFIGARVVGSSTFTLKSADKFGVVSIDREAVSMIEEWVAFQNADKFLMVDEAG--GKVRADADSIGFCE-TFRVYCQARFK-RKVKIKKFQIKRAKKEGNLSETLLDRRSKMKADRYCK Ustma22 RLSFKGDKKKRKRSSTKAWVRVEDLN-GPCFLFQRRAHCVAFQPSVEAAAILGLIPTSVYQVWIATKVPGSSEFTFKSADKSGLLRARIEARGPQEEWWKLRSVNRYLGSDQAG--GVVRADCEHADSEA-IWNIKVQWKHR-HAARFKSRALRKAEKEGRLAEEMLDRRSKLKSDKYA- Walse1 ------------------WVRATHIN-GPTVLLHSQ-SVLNFHSKPHMHSLNGFTPSDVASVWVASRLSGTDTITLRSADKHGSVSAMNEARGPNEQWIAWMSIDKFLSLDEAG--GVLRADSDTVGFGE-TWSVKVQAKYK-YEGEQHTFQLSKAKQEGKLNEALLDKRSKTK--RYVQ Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster2921.fasta_al_trimmed; alignment length = 150] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 LVIALITTAAVLIISKKRVPIFIIAGPSGSGKTSLTVASQIASFSLIDFPGHVKTTLKASSNGLIFMVDSTVDVTETAEFLYDVLAID-IMIACNKSESFTSRPPTMIKDALEKELGQIIERKSKDLFKLDHLEA-AVQVCAGSVAWLDE Aspfu1 TLIAFGLPVLLHFLRSVASSNFLLLGPSGAGKTALTSTSAIVSLPLKDTPGHGKSELVSMATAVIFMVDTAALLRDTASYLHDVLEIP-VLVAANKQDLFTALPPGSVREKLETEIDRIRKSKSKGLFSFRLLEGVKVDVVGGVVEWIGQ Aurde31 ------------------------------------------------------------------------------------------------------------------------------------------------------ Batde5 SAVILVIALLLSAWAVGSTDTVVIAGPSGSGKTALTCVSMQENVALVDIPGHLRNTFLPSAKGILFVVDSSQLLRSTSEYLYDVLELP-VHILCNKNDVILSLTPALVKSMLEQEINQLRKARSSGIFKFEHLSN-EVTFASISCEW--- Botbo1 AFIAAI-FFVALVYRRG--SAILLVGPSDAGKTAITHTSIQPTITLIDVPGHPRTEYLPDAKAVVFVVDTSTI---VAEHLHLILTPPALLLLAHKADLLSRLATERVRTVLERELEKRRIAASGSVFSFSRWDGGAVECAGTWVRWLEE Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel AVIGLLTVLLLVL----ASNRVLFVGLMDCGKTTITYTSMVENKIIIDYPGNDRENHLHSRSRIVFVVDSAAFARDVAELFYTVAKVP-ILIACHKQDLSLAKTEKVIRNSLEKEIGLINKSRAAALFKWEDLKKQEVSFVSTSSSFVRA Canalb1 FVLILI----IFFISKKSSPTFLILGANNSGKTSFTVSSLEPNVTLIDYPGHLKIDEITLKNGVVYMIDSSSVLESIVKFLYNLFGVD-FLIAINKTDLFDSVPVHKIKTKLELEINKLIRHEIENVFTFDKLEG-NVDFVGGSVNWFDE Cangl LVLVILTTL-LIAFSSSYVPTIIIAGPSYSGKTSLTVMSQEPSFALADYPGHVKNGIIDLKGGILFVLDSTIDITETAEYLTEILPID-ILIACNKNESFTARQPLKIKEALENEITRIFERKKKSLFKFDYLEG-NVEVLAGSVEWVGS Capow LTVLAIAAAAVYL----GSSAVLLVGIANSGKTVLTFTSVVPNSGVVDIPGHDRDELATDAKGVVFVVDSANLLRTMSQFLYDVLAVP-VRILCNKQDLLTAMDSDNVKSQLETELNIIRKTRIAAPFNFEQLGS-QVTFMEASGDWIAQ Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin LLVVVVTAVLWKLF----KTGVLLAGLSDSGKTILTHTSLKENEAVVDLPGHEAEKYKDNARGIVFVVDSGSFVKDVAEFLFQIFAPS-ICIACNKQDLFNSKTKTVILNQLEKELNTVRKTQSAALFQFSHLSKFKIEFLECNAMWISS CocheC53 LLVALLLPILVHSFKAAAAPTLLLVGPSGSGKTAFTPLTVSAQLPLLDTPGHGKSQL-----AIIFMLDAAQLLTEAAEYLHDVLEIP-VLIAANKMDLFTALPEHLVRNSLEKAITEIRNNRAKALFSFEQMGRTSVQVVGGNVKWIAE Coere1 ------------------ETAVVITGPMSTGKTALTQMSMGINAALVDVPGHQKDTQLQAARAVVFVIDSAAVIRPTAETLYDVLECP-VLVLCNKQDDPMALSNARIKGLLEDEIDSLRTSRQAGLFCFEDLSQ-PIQF---------- Conco1 IVAVITVLIAVY--WLARKNVNLFIGLPNSGKSSFTHTSYKSNQGIVDCPGSEQKSLVSGTDKIYFFIDSSTVRSEIGELLYEILQTP-LYLVCNKQDLPNSVLPEKVEEILEAEINSIRQTIGKNIFKFNHLTN-TVRLVSASLD---- Conpu1 LALLLA-LVALYVITRG--NIYLLVGLPDGGKTTISHMSLQANSSVVDIPGHPRREHLQDLRGIMFVVDSNSV---VAEHLHLILTPPHVLIVAHKADMLKATAVTRVRGALERELEKRRVTQAQGVFKFTEWEGGDITFVGSFVDWIAE Copci LLFAVV-LVVLLILGQG--TALLLVGPSDSGKTAITHTSLQPNASIIDIPGHPRTEYLSDAKVIAFVVDSNTI---VAEHLHHILAVPSLVVVCNKADLLKTLAVNRVKTILERELEKRRLAQTGGVFRFDEWDGGDVVFLGTSSDYLEE Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 GGLALL-LLFLTFFKRNG-ATVLLVGPSDGGKTSLTHTSIVPSDTLIDIPGHPRKKYIADSAGVVFVMDIQGI---VAEQLPPILPPPKLLLLAHKADLLARASTDRLRSILTREMDRLKSTRGGTGFKWEDVEGVEVEWGASGLAFLWD Crypa2 GLIVLLMPLLMHYWQAATYPSILLVGPSGAGKTTLTWSSTEL--AMVDTPGHGKGRLTP---AVVFVVDAAALLADTAAYLYDVLTIP-VLVAANKTDLFTALPAKLVKTNLEKELGRIRKTRSKGLFKFEQMRDIDVDVEGGAVAWIGN Debha1 LVVTLL----IFCIGGRSQPTFLIIGPNNSGKTALTVSSIEPNVKIIDYPGHIKNEDITLKNGIIYVIDSSSNVKLISKQLFTLLGID-FLFAVNKQDLFDSKPIHKVKEILELEMTKLIKNELLTKFKFELLEG-SMDFVGGSVNWIDE Dekbr2 LLVIIITSFIV-------KRTFILTGPKKSGKTSLTVTSIEPSVGIRDYPASSKKENIRGCKGLIYVIDSSCFCNMVANDLLDLLGVD-IAIFCNKCDYFTSRKPKKIKEMLENEITKLYKLKLRNLFKFEMLEG-NVDFLEGNAVWFCE Dicdi LLLALFTLIFIIIINDKKVVNIAILGLSNAGKTALTHTSITTNNGIIDVPGNGKPKILSNSACIIYVIDGTTFSTQEAQYLYDILKIP-VLVFNNKMDLDSTIDTEQVKNILERELDDLRRTRGATPFQFDHLPN-DVQFSNGSANFIQT Dmel IVALLLGFIAVAIF---RSKDFLLTGLSESGKSAITFTSIKENVGLVDIPGHYRELYKHRAKGIVFVVDSVTAIRDVADFLYTILPCS-VLVLCNKQDQTTAKSAQVIKSLLESELHTVRDTRSRKLFEFSHIAQ-NIQFAEASADWLAR Enthi TTVLLLIGIIVYVI---NKSVVMITGISGVGKTSLTCTSMVENIGIVDIPGYGKKKYIESAKCIIFMIAGDEVIKDDAGYLHCIINIP-ILILCNKSDIPMSESKDIIKILLEKELNKLRVRVAKPGFHFEQLKS-KIEFAQSSVNFLSG Falba ------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 LVIALL-VIAFAVSKRG--NLILLAGNEDAGKSAVSHTSFQVNSSIVDIPGHPRKTYVPDAKAVVFVVDASAI---VAEHLHHVLSLPSLLILAHKTDLL--LAISRVRTVLERELEKRRSVAAGGVFRFAEWEGGEVGFAASYVNWLED Fusgr1 ALIVLGAPIILHLLSSRTYPSVLLVGPANSGKTSLVSHDVELNASLIDTPGHGKAKL-----AVVFVVDAAAILAPTAAYLYDVLSIP-ILIAANKMDLFTALPSTLVKTNLEAELTRIRASRSKGLFTFSQLQDIDVDVLPGNVWWIAQ Galma1 LGVALL-FVIALFLSRG--NTFLLVGPPDAGKTSITQTSMQTNSSVVDVPGHARQEYLPDAKVIGFVVDANTV---VAEHLHYVLPQPALLIIAHKSDLFKSLAVNRVKAILERELEKRRVSQSGGIFKFDEWEAGEITFIGTSIDYLVE Ganpr1 LLLLLAAIAALALL----KDAFIIVGLSDSGKSTLTVTSIEQNEAIIDLPGHPTSDYTPLALGIIFVIDAATFSRSVAERLYDVLGIR-VLVVCNKQDSFVAWPREKIAQALEKEIDYLRTTRTATLFRMSHLDT-DVRFVECALRWIEE Gloin1 -LAILIVIIAIAL-----RDTFLILGLVDSGKTSLTHTSMKENEGFVDVPGHEKSDFTPITCGIIFLVDSSTCVRSIAEYLYDIFNIP-TLIACNKNDMITALPPERIQTMLENEINQLRNTRTSALFKFEHLEN-EVNFEKCSVSWVAE Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 CIIVMISAAFVLIVASKYTPTFIIAGLPQTGKTALSVMSQEPNVALIDFPGHDKQTIKDSSQGLIYVIDSTINLVSTAELLYEILGVD-ILLACNKSESFVARPPSKIKGALEKEITEIMKRKAKSLFEFDRIDG-NVDAKEGSVCWIDE Lacbi2 LSVAVL-FLALLFFSRK--NALLLVGPPDAGKTAITHTSLQTNQSIIDVPGHPRQEHLVDSKAIAFVVDSSTV---VAEHLHSILKLPSLLILAHKADLLKTLAINRVKTILERELEKRRASQVGGVFKFEEWEGGEVIFLGTSVVWLEE Lenti61 LVFAVV-LVIISVFQRG--DAVILAGCSDAGKTAITHTSMQTNAALIDVPGHPRQEYLPHAKAVAFVVDSSTI---VAEHLHMILGTPSLTIVAHKCDLMK-LAINRIRTILERELEKRRASHANGVFKFAEWEGGEVGFVGTSVEWLED Malgl1 -------------------PPALFVLFTRMDRSPLTLVSRRASRG----PAQGRRSWMERARRVPFLQWVGPT---VPAELHPTRELA--------NDYIMA--------ALDEPLQRLDPR-----LAFIDRTG----------TWIET Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------ Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 LILLTLIALAVNF-----RNTVLITGLPFAGKTVITVTSIKENEAMVDIPGHERSEFMPIARAVVFVVDSATVTRLLAEYLYDILRIP-VLIACNKTELLTAFRKERIQTALEGEINKLRQTRTAALFSFQDLEN-EVEFLECSADWIAS Mucci2 -LAVLLVVTVIGL-----KNTVLLLGISDAGKTAMTVSSMKENEGLVDMPGHDRADFLPVTRSIIFVIDSTKVIRPVAEYLYDVLRTP-ILIACNKADMITALPTEKIKLLLETELNRLRGTRTARVFKFDHVDN-DIEFESC------- Mydma LV-----AIISGFF----KT-VLLLGLCDSGKTLMTQTSIIENKGVVDLPGHERYKHKDGARGIIFVIDSVNFLRDVAEFLYDVLKVS-ILIACNKQDMPTAKSSQVIKLQLEKELTTLRQTRSAALFEFAHVNPIKVQFCECNLNWMNS Neucr2 LLIVLLFPIFLHQVSSSKNPSILLAGPSGAGKTALTPVSIKLNAALIDTPGHPKSHLLPLDPGVIFLLDASTLLSQAATYLYDLLSIP-VLIAANKLDLFTALPATLVKKELEAELGRIRVSRSKGLFEFRQMVDIEVEVMGGSVRWVVE Orpsp11 ----VLVIL---------KDTFIITGICDSGKTSLTHTSIAENEEVIDFPGHYKQDFTPITKGVIFVIDSATFERDVTEYLYEILEVS-VLIVCNKQDYITALAKERIKTSLENE----------------------------------- Pench1 ILFTFGVPIALHILQTVASSNFLLLGPSGAGKTAFQSTLVTVTLPIKDTPGHGKSELQTMTQGVVFMVDTAALLRDTATYLHDVLEVP-VLVAANKQDLFTALPPGAVKEKLEAEIDRIRKSKTKGLFSFKLLEGVKVDVVGGAVEWVGM Phybl2 GIVTLLAAVVASF-----KDTILLLGVSDAGKTALTVTSMKENEGLVDMPGHERSEFLPVARGIVFVVDSTTIIRSVAEYLYNVLKLP-VLIACNKADMITALPKDKIQTLLEAEINRLRGTRTAAVFKFEHLES-IVDFEVCSVGWIES Picst3 LVIVLV----LFFVSSSSPPTFLILGANNAGKTSLTVSSIEPNITLVDYPGHLKLEDITLQKGIVYVIDSSSQIEVISKYLFNLFGVD-FLFAVNKNDLFDSVPVHKVKSVLEAEINKLIQNELNTVFTFDQLEG-NTDFVAGSVNWFDE Plicr1 FVLAVL-CIAILVLSRG--NAVLLVGPPDAGKTAITHTSLQTSSSIVDVPGHPRQEHLPSAKAILFVVDASTV---VAEHLHHILPLPALLILAHKSDLLKSLAVTRVKTVLERELEKRRTSQLGGVFKFAEWEGGDITFVGTSVEWLGD Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 FSFAVL-LLALFVYTRG--NAVLLLGASDAGKTAITHTSIQINATLVDVPGHPRREYLPEAKALMFVVDASTI---VAEHLHHVLTPPALLILAHKYDALKTLAINRVRSILERELEKRRATHAGSVFRFADWDGGEVEFLGTSVQWLDS Rhior3 -VTILL----------------LITGICDAGKTSLTVSSMKENEG----------------------------------------MLL-IYLVMNVFAIVMS------------------------------------------------ Rhoto1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 CLLVIGTTIALIAVGIKQKPSIIIAGPQNSGKTSLTVVSQEPLSALVDFPGHVKDYLKTRAKGLIFMVDSTVDLTTTAEFLVDILGID-ILIACNKSELFTARPPSKIKDALESEIQKVIERRKKSLFKFANLEA-SVVAFEGSIEWIDE Salro LAVLGILAVVVVF----AKDTVLLVGPLGTGKTTLTQTSLKPNEAVKDIPGHERGESAASCAACVYVLDSSTVARPVAEFLYDVLAMP-VLVLCNKQDVVTARKVERIVQKLQNEFTQIRQTRSADVFEFSQLPN-RIDFELTSLDWVAR Schco3 LAVAIL-LVSVLVLTKG--NALLLVGPPDAGKSAITQASLQTNSAIIDVPGHPRRAHLPAARAIAFVVDASTV---VAEHLHTLLTTPCLVILAHKCDLLKSLAASRVRTVLERELERRRAAAAEGIFSFDTWEGGEVTFLGTSTAWLED Schpo1 TIIIGAIISTLGIFRKTIQPAVFLIGPSDSGKTSLTVPSIEPNEALVDLPGHPRTKF-----AVVFVLNSATIVHEVGLMLFDTI-VPHLLIACNKFDLFTAQPAEKIQQLLKAELHNILEEKN-----ADQIEDTDLKFLPGSVSWMES Sorma LLIVLLVPVILHQYSSS-SPSIILAGPSGAGKTALTPVSVELNAALIDTPGHPKNHLLPLDPGVLFLLDASTLLSQTATYLYDLLSIP-VLIAANKLDLFTALPATLVKKELEAEIGRIRVSRSKGLFEFRQMQDIEVEVVGGSVRWVVE Sphar --------------------------------TTLTHSSLKTNTALYDIPGQYRDQLAATAKAVVFVVDSHTCIADVSAWLYTVVRVP-IVLACNKQDMFGAPSPTAIAASLLAEMNKIRTTRMS--LAWADLPN-TIVVMGCSIEYISS Spipu1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 LSLAVL-VIAIFAFSRG--NVVLFVGPQDSGKTAITHASLQTNTSAADIPGHPRREQLPNAKAVVFVADATAV---VAEHLHQVLAAPNLIILAHKCDLLKTVAINRVRTVLERELEKRRASQSGGVFKFAEWEGGEIEFLGTSVQWLEE Tapde11 STLVLATILAVAFFNIPLAPTLLLVGPSNSGKTSLTCTTQLANTGIVDVPGHPKKSFTPTS--IAFVIDSSTI---VTRLLIDVISITELSILANKSDFFT-LSTEKITELLEAEIEQIRQ-QKSGILKLADEC---LMFSGSVLEWVES Thetr LAMAGLVVAAVMVVTSSVRSCVVLLGESGTGKTTLCHTSMEENRGVLDLPGHPSHQAVSSAAAVVFVVDAVAALRVTAEHLFTVMATP-LLVFCNKADVPSACSPLALENALADEISTLIDMHTSRLFDFAAVP--TVRFTAGAAEFVSH Treme1 VGIFIL-VLFFTFFQLN--STILLVGPSDSGKTSLTHTSIKSSTTLVDLPGHPRTKNLREADGVVFVVDIVGL---VAEQLPPILKPIKLILLANKTDLLIRIARERLRFILTREMDRLKSSRASASFKWEDVEGVEIIWAASGLGLLEE Trire2 IILILGAPILLHLLSSSTYPSVLLLGPDNAGKTALVAHSIELNASLVDTPGHGKGRL-----AVVFMVDAAALLAPTAAYLYDVLSIP-VLIAANKMDLFTALPATMVKSHLEVELSRIRASRSKGLFTFQQMGDINVEVLPGSVWWIAQ Umbra1 LVVLVLAIIAIGLI----KNTYLILGATDAGKTALTITSMKENEALVDVPGHERADFMPIARGVIFVVDSTTVARTTAEYLYDVLRIP-IIIACNKTDLFTALPTSKIQTLLEAEINRLRATRSAAVFKFEHLEN-DVTLIGCSVEWIAD Ustma22 LTYTLTSLVSAHSDNRP--STVVLVGLSDAGKTSLTVPSQTMSQGVVDLPGHARDEHLHQADGLVICVDAVTAITDVADLIHSTLAPPCVLVLFTRADLSPLQLLARCKTTLEAELGQRRANTAGGGVDYIDWAGGKVEFALASVRWIAD Walse1 VALSLL-AILISVL----TKDILLAGPSGSGKTAI--TSANSRASIVEIPGHERKTHLPAKR-VLYCMDYKHLVQHLSGFLQAV-NTP-VVIVLTKYDKQSQSLIQRSKNTLEFELNKIRKS-----YPFVVVG-----------EYIH- Zygro1 IILVLITTA-LFTIASKVTPTFIIAGPSESGKTSLSVTSLEPNVALIEFPGHLKETLQNSSNGLIFVVDATVDLTSTAEFLFEILGVD-ILIACNKSESFTARPPLKIRSALEKEIERIIIRRQKSLFKFESLEG-NIDAVEGSVCWMDE [Cluster2922.fasta_al_trimmed; alignment length = 74] Allma1 -------------------------------------------------------------------------- Ashgo11 GKADKKQAAANTAALRRLRLARVGV--ALD-ASSGLTGALFDVVYTSVAAALGWWLLFAWPVYWAY-------- Aspfu1 QKAAKTLAARNASLLLRTSLRSPGE--DLG-ASG-LTEYMWDVLYWTWACLFGWWLWIVIPIYSVWRQKKMEKR Aurde31 NASAKKTAAQNEAALRNLELISSGD--DLS-QAG-VIEWAHDVLYVTWSALLGWYLYLAIPVYAIYRQEKLKKR Batde5 GASARKTLARNKKIITQLNMANTGT--DLA-QEGTMISYFYDSIYITWVCVSDYWTYMLIPIFAIYKTAATRKS Botbo1 NASAKRIASQNEIAIRNLTLISSGE--DLD-ARG-VTEWCWDVIYVTWSALLGWFGYLSIPAFACWRQQKMQKR Botci1 QKAKKDRAKANIQALNYLKMVSAGE--DLA-APG-LTEYMFLVC--------------------------REQR Caeel TKGQKEIYEENQKTVTTYHVLDAGA--DLN-DPEAFGEYCKDAIILTVSLYSTFLLLLAFPGAATYKQKKLDRR Canalb1 SASAKKLAVANTNILNQLSLVSSGE--DIR-LSGSLYEYYFDVIYLTWMIIFGWYGYLIIPGFAIYRQQKLQAR Cangl GKATKKQAASNSNTLNTLKVVREGM--DLS-QAGGMTEYMFDLIYLSIRIIFNWYLLLLCPIYVGYRQMKREKR Capow NSSNKRIYEANKRILSLHELLDAGH--DLD--AGGLSEYYKDVIYVNCSVFFNWLIWAVIPVFATYTAKRLAKK Catan2 -------------------------------------------------------------------------- Cioin TKGAKQIKEENRTTYNFY-------------------------------------------------------- CocheC53 QKATKTLAASNTKRLNQTAVKRPGE--DLD-AKG-LTEYMWDVVYWTYAAIVGWFLWTVIPAYSAYRQAKMEKR Coere1 KQSAKRIVQENAARVAVLILVDSGT--DLK-QPG-LVSYMFDYVYISWLSLFTWMVYLAIPAYFVYRREKKERK Conco1 NQSGKKILANNQKILKYLGVPKGGQFIDLS-DPG-VISYTFDILYIIWSTFTSWYLLLSVPAYAFYRQQKLKKR Conpu1 KGSVKRIAGQNAQTIKNLTILSSGE--DLG-QPG-VTEWCFDIIYVTWSGTLGWWFYLVIPFYAFFRQEKLQKR Copci NASAKRIANQNEAAVKQLALISYGE--DLN-QPG-VTEWCFDILYITYSGAFGWWLYTVIPLYAVYRQEKLRKR Croqu1 -------------------------------------------------------------------------- CryneH991 NASSKRIASGNEAALWNLAQVKVGD--DLG-GKG-VIELGWDLIYMTWSALFGWWLFTLVPAFGAWKQAKLRAR Crypa2 QKAKKDRAKSNAAALNNLALKSSGE--DLA-ARG-LTEYMWDVVWVTWVMLFGWLLWAVVPAYGAYAGNRKQRR Debha1 SQSMKKLAAANTEILKQIKLLKAGE--DVK-HEG-LYEYMFDTMYITWMIVLGWWLYSIIPGFAIFRQAKREAN Dekbr2 GAAEKKQAKYNVETLKQIMLVNAGE--DLR-QQG-STEYIFDVFYLTEMCLFGYLILLLIPIYAVYRQKKLEAR Dicdi NSGAKKRKTQNEKELFKVELIDGGS--DLN-QGG-MTEYYFDIIYVCCG-LISLYLILVIPAFAIFRREKMEKK Dmel TKGAKQIVEENKTTLTFYALLDSGN--DLN-MEGGIAENVKDLIILTSALISNWLVLLLAPIRAGWKQKKMDRR Enthi NQSQKKTVVRNKQKL---ELIDCGS--DLS-AEG-LMDYIHDILYFSSSSFSFMYLYILVIGYTIYEKGKKQKM Falba GQAEKKRAASNEARLQLLPLVSVGA--DLT--IG-VANLIGDSAILCWRPILGWYFLLTIPGLWAYKQKRKVIR Fomme1 ------VAAQSQKALQNLNLLKSPS-VDLA-NPGFVCEWMFDVLYITWSALFSWWLYLTIPGYILFRQQKLKAR Fusgr1 QKAKKDRAKSNAAALNNLALRSAGE--DLS-SPG-LTEYMFDVIWVTWVIFLGWFLWLVLPAYGLYPGNRKARR Galma1 NASGKRIANQNENTVKTLTLISSGE--DLS-QPG-VTEWCFDILYITWSGTFGWWLYMVIPLYAVFRQEKLRKR Ganpr1 RNSDKKLLVSNARTLRTIELVHAGE--DLG-AEG-LTEYLLDLVYMAWTAWSYWWLYLGVPAFAGWRR------ Gloin1 KQSDKKIAQENLRYLRNLTVIWPGE--DLN-SEG-LTAYMFDIIYITWSMFFAWYILLVIPSFAIYRQKKLEKR Hisca1 QKAAKTLATRNTSLLNRTTLRSAGE--NLD-APG-LTEYFWDVMYWTWVCVFGWWLWVIVPLYSAWRQKKMEKR Klula1 GKSSKKIAAKNAAILKQLKLVNEGF--DL--ESGGLTEYMKDIVYVSLTVFFNWFLVLVCPAFIFYRQLKREKR Lacbi2 NASAKRIANQNESTVKTLTLISYGE--DLH-QPG-VTEWCFDILYVTWSGVFGWWLYMVIPLYAVFRQEKLRKR Lenti61 NASAKRTAQHNAETIKNLALISAGE--DLA-RPG-IIEWCFDVVYISWSGAFGWWLYLVIPLYAVFRQEKLRKR Malgl1 RGAQKRVSQANQRAVATL----VGD--DLS-LPG-MTAYMFDFVYITWVALVSWWTYAVIPMYLSYRQAKMQAR Mellp23 -------------------------------------------------------------------------- Mnele AKGEKDIAVGNVATLDFYNLVSAGT--DLN-MEGGVTDYFKDIIIVTCSLISDWFCWLIIPGFALVQQEGFKKG Monbr -------------------------------------------------------------------------- Morel2 NSSQKKIAHENSKTLLSLELVDAGQ--DLS-QEG-LVQYAFDIIYVTWSAFWSWWFYLAIPAYAGYRREKMEKR Mucci2 NASSKKIAATNKQTLKNLNLISSGD--DLN-AEG-LTAYMFDIIYVTWTAFISWMVYLVIPGYAAYRQAKLEKR Mydma KKGQKQIDKENAGSLQFYSIVLGGM--DLA-MEGGMAEHAKDLILVTASLVSNWFLWLVVPGRAFYQQKKYEKK Neucr2 QKARKDRAKSNETTLKNLALKASGE--DLA-APG-LTEYMFDVVWVTWVTLFGWIFWTVVPAYGIYAGNRKQRR Orpsp11 -------------------------------------------------------------------------- Pench1 QKAAKSLATRNGAVLSRTSLRSAGE--DLN-ATG-LTEYMWDVLYWTQVCLFNWWLWVVIPLYSVYTQLKKEKR Phybl2 ------------------ALVASGD--DLN-AEG-LTAYMFDIIYITWTAFISWYLYLVIPAYAAYRQAKMEKR Picst3 SQSSKKTAQANTTTLNQLKLVRSGE--DIH-HEG-LYEYFFDIIYVTWMVILGWFLYLAIPGYAGYRQTKLEAR Plicr1 NASAKRIANQNDTAIKTLTLVSSGE--DLN-QPG-VTEWCFDVLYVTWSGLFGWWLYLAIPIYAGFRQEKLRKR Polpo NQGAKRRKQQNESEIFKLELIDGGA--DLS-MKG-LVEYYFDTIYICLG-LFSFLIMLIIPVFAFYRREKMEKK Pucgr2 ------------------GATQTPD--DLS--TG-IHQYIVDYCYISVTGLISYWILLV-------REFQLQIY Punst1 -------------------------------------------------------------------------- Rhior3 -------------------------------------------------------------------------- Rhoto1 GASNKRIAAANARTLKTLAMARRGE--ELDGSKG-LVSYAFDIVYVTWAALVTWYIYWVIPLYALYRQQKLRKR Rozal11 -------------------------------------------------------------------------- Sacce1 GKAGRKQASSNAKIIQGLRVVKQGI--DLN-DNTNLISYFFDLIYLSLIIAFRWWCLLLCPIYAGYRQMKRERR Salro -------------------------------------------------------------------------- Schco3 KAAQKRIANQNESTVKTLTLISYGE--DLS-QPG-VTEWCFDILYITWSGAFGWYLYLVIPLYAIWRQEKLRKR Schpo1 NAAQKKLAAQNKHILTFMSLLYVGQ--DLL-QEG-VTSYMVDYMYFSWAALTSFYLL--VPIFVVYRQQKLRKK Sorma QKARKDRAKSNETTLKNLALKASGE--DLA-APG-LTEYMFDVVWVTWVTLFGWIFWTIVPAYGLYAGNRKQRR Sphar -------------------------------------------------------------------------- Spipu1 KGSAKKIHEKNTQTLSNLVIEDAGA--DLS-AEG-LVAYMFDIIYIGWTAVISWWTYLVVPGFAAYGEHYLIGF Sporo1 GANSKRIASENAKQLTVLTMASRGQ--SISDGKG-LIQYMFDLIYITWTALVSWYLFWVIPGYGLYRQEKLRKR Stehi1 -------------------------------------------------------------------------- Tapde11 RQAEKQLAKSNVAKITLLSLKSSGE--DLG-QAG-LTEYLTDLVYITWVKVVQ-------------H------- Thetr ---------------------------DIS-TGG-LSEYFADVLYLSWASYSMFWVFITIPIFALYRKERRKER Treme1 NASSKRIVSANETALKNLGKVRSGE--DLG-GKG-VVELAWDLIYMTWSALLGWWLMLLIPIFGTYKQAKLRVR Trire2 QKAKKDRAKSNAASLNSLALKTSGE--DLA-AAG-LTEYMFDVIWVTWVILFGWILFATVPAYGAYQGNRRSRR Umbra1 NASSKKIAANNAKILANLSIASGGD--DLN-AEG-LTAYMFDIIYITWTAVISWYTYIVIPVYAGFRQAKLEER Ustma22 RGSAKKTASGNAFLLRLLSMAAQGN--DLQ-QSG-LTQYMFDVIYVTWSLVWSWYLYLIIPGYAAYRQQKLQAR Walse1 NASQKKTTAGNQKSIRILQILSSGE--DLS-AEGGLIEHIWDVVYINWTGFFGWWMFIIVPAFALFRQQKLRQR Zygro1 GKSSKKQAQSNLLVLRNLKLIREGL--DLS-QSGGLTEYMFDVIYLSLHILFNWYALILVPVYAIWRQAKLAKR [Cluster2925.fasta_al_trimmed; alignment length = 160] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 RPAHIILNGLDRYNPETTTVFQDYVVQQCETFDCYANLALLKLYQFNPQPETVTNILAKALTSPAFSLCLALLPATLLESAQYAQFWSLVADVAGFEELVRIRIAIEVGKAFREINQWLDLRS-REALEKFV-TEVKVPTNKENEAR-SEVKSERVGVEM Aurde31 RPEGILVSGVDRYNPSNISVLEDYLYHQIREYDCFANLAVLKLYQFNPNPDVAINILLKALCLPDFNLCVALLGQSLLLRCRFPAFWAYTVEFTGFEDAVREVVVRAVRATFKRIASYFNLQG--EELDAYI-AKVSVPANPDNTIQ-ASVVRENIQFNQ Batde5 RPEEIVVETVDRYNPQNMAILEEYISSQLKNYDRTACLALLKLYQLNHNVYVIASVLALALSESDFTLCMYLLREELLGQAQFSEFWAFTGDYSLFDDNIREFIAQTLSITYQTISKMLDLSD--EDLADWVKMRIDLPITSWNQAK-EIVMQEDVKFEQ Botbo1 RTELILVDGVDRYNPSNLGLLEDYLYHQIREYDCLANLAILKLYQFNPNPDVVINILVKALTLPDFNLCVALLGESLLLTCRFPAFWAYTVEVTGFDDSVREVVVRATRAAFVKIGRYLHLDG--SNLDKYV-SSVSIPPNPDNQIE-GQVVRESIQFPQ Botci1 RPEHIILNGLDRYNPETTNIFQEYVTLQCETYDCYANLALLKLYQFNPKDETITNILVKSLTSPDFSLALHLLPPTLLSSANYSQFWSLIADVSGFEELVRIRIASTISQSVREVANWLGMNG--EAFEKFI-KEVIVPLNKENEAK-GTVVRENVKMEQ Caeel LQKELAIEGVNRYNPENVADLAACVQAMVNKYDKDIVLTILKLYQLNPDEAVVRQVLLKTLMSSDFALAKCLIDTAVLESCNFAVFWKMIKPMVGFEDAVKHYACRVISVTFQKIERLLGGAS-DKEVTALA-QSVFFVANHEGTIK-TRNIDEKIQFPH Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow GAADLLLKGTDRYNPTHIERLEKYIQEQVTTYDFESNLALLRLYQFHPNADASAQVLLKMLLAGDYASSLFLLSDHHLEAAQFIQFWSIKQLMPSFADEARKFIAHILSVSAQSMDKFLDLQA--GAFDSFV-AAVSFGVNKDNQAK-SKNISEKIPFNN Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ANR-IMLKGIDRYNPENLGELEPHVKQQLATYDLPANLAILKLYQFNPQVDIVCGILLKALTSADFSLCECLIDQHLLETCDFKLFWRLTEGVVGFEDSIKKFICRTVSISYQRIGSLLGDLG-DEELNRWI-KVLVFVANQEELVK-TRNIVDKVNFEK CocheC53 RPDHMILDGLDRYNPETTSVFQDYVMQQCETYDCYANLALLKLYQFNPRDETITNILVKALTSPDFSLGLSLLPPNLLEGADYATFWSLIADVSGFEELMRVRIAATVSQAIREVDSWLNLSG--SEFDHFV-GSIKVPINKDNEAK-GTVVRENVKFDQ Coere1 RPDEILLTGVERYNPQKIGVLEDYLAHQCANHDLMANLALLKMYQFNPDLDVIRRILAKALIQGDFNLCLYLLSDDYLEKAQFDGFWSVVDGIAGFDNGLRKLILAEITSTYQTIQKMVNLDE--EAVLRLA-KEVSLPLKSENEAK-TTVIKESIKFEQ Conco1 RPEEVILSGIELFNPDNLPRLEHYFGVQCREYDQLANLAILELYQFNPNPSIIVSILAKALTGPDFNTYSCLLTQKLFQTGQFEEFWTLLGEISNFKTSMRLVISQIISVTFQQISKFLNLKDNEEEFNTLI-QTVKIQSNQFNEVK-QGNVDETIKVQQ Conpu1 RTELILVSGVDRYNPSNVGILEDYLYHQIREYDCLANLAILKLYQFNPNPDVVVNILLKALTFPDFNLCISLIDDNLIHQCRFPAFWTYTVECIGFEDSIREVVARAVRATFTRIGSYVDLQG--EELEQFA-ARFVIPSNPDNQIE-AIVVQESIKLPQ Copci RPDLILVSGVDRYNPSNVGILEDYLYHQIREYDCLANLAILKLYQFNPNPDVVINILLKALTMPDFNLCISLLDENLLYRCRFPAFWQYTVEVVGFENAIRQIAIRAVTATFTHITSYLNLDG--EDLAEYI-QQVAVPPNPDNQIE-ATVVQEQIKLPQ Croqu1 RPKQILILGVERYDPTQVQVLEDYLASQFNFYDPLANLATLKLYQFNPHDSVTVKILLLSIADSDFSLGLSMCGDSTLQSRKFATFWDLVSTVRDFDNLIRRSIGQSVASCFRSISSYLGLSD-EGQVRKWV-QEARIPDNSDNRPV-TTVTRENTTLED CryneH991 RPDVILIHGVDRYNPSNLPFMEDYLASELKQYDLFANLAILKLMRVT-NPDVIINILIKALSGPDFNLCLEMLREELSRTCQFTKFWQYLTQHASPLDDFRFIFSASIASCFRRISRWLDIPS--DKVGDWC-SK--IPNNGQNDVK-AGVVKENVQLGQ Crypa2 RPAEIIINGLERYNPEAVGPLEAYLQQQCEYCDGNANRVLLKLYQLNPKDEVITNILVKAMTSPQFDLALHLL--AHLEGASFARFWALTTDIDGFEETIRVRIAQLVSEAFREVQDWLGLEG-KEAVEKFV-VEVVVPKNADNEAK-KAEIREDVNVEM Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi RIEYILIA--DSYNIAIAKKLEEFLDIQINTYLFQANSTLLKLYQFNPNKDSIAKMLAKALMCNDFLFLSYMIPSNFLETCKFKEAWTFFSEIPSFIDNIRNFISGVLSITYQNISELLNLSDRTQLVDYIQ-SKVSLQSDNSKQKK-----ADTFTFDQ Dmel QSQTIMLGCIERYNPDHLKTLESYVQDQAKTYDLEANLAVLKLYQFNPNFDITYTILLKSLTHTDFVMAKCLLLPDILERADFTLFWQMFRHITGFHDSIRKFVSHVVGTTFQTIRELLGGIE-DSTLESWI-KRLVIVAMQDDKIK-TKNITEKIEFDN Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -----VL-------PEQISQLETSVAAQFSEYNLSEMMNLLKFYNFDPRGLIVARIIIKSLTRADAAAACYLLSAEQFECIRLDAFWALIEPVVGFFDNIRDVIAGVVSITYQRLSTLVNLSG--AELTQFI-SSLSLPLVPENTSSDGSVVSDNIQLPQ Fomme1 RPELILVSGVDRYNPSNVSILEDYLYHQIREYDCLANLAILKLYQFNPNPDVIINVLIKALTFPDFNLCIALLGEDLLLQCRFPAFWTYTVECAGFEDSIRKVAIKAVKAAFKKIGTYLDLKG--EDLVDYL-SHVSIPPNPDNQVE-ATVVRENIQLSQ Fusgr1 RPQEIIINGLERYNPEAVGALETYLQDQCEFTDCNANRTLLKLYQLNPKDEVITNVLVKTMTSAQFSLALHLI--GQLEGAQYSRFWALIADIPDFEEVVRHRIALLVSQAFREIQSWLGLN--EDATKKFV-TEVKVPSNPDNEAK-KAEIREDVNVEQ Galma1 RSELILVSGVDRYNPSNVGILEDYLYHQIREYDCLANLAILKLYQFNPNPDVVVNILIKALTLPDFNLCISLLDENLLFRCRFPAFWEYTVEVVGFENAVRAVAIRAVRATFTRISSYLNLNG--PALTAYI-QKVTVPPNPDNQIE-ATVVQESVKLPQ Ganpr1 RPQEIIVETVARYNPENIEVLERYVTTQLNTYDRDANLALLKLYQFNPNLEYVAAVLAKALTDPDFNLCLALITDQLLERCSFVEFWRALDACKGFDEHVRDFIARTTVLTCQTVSDWLNLSA--EEVREFV-ADVVLPVTKENAPK-VKGEQEVVKFEQ Gloin1 RPDVILIDGVDRYNPDNVSILEEYLSTQLQEYDLMANLAILKLYQFNPNDVVISNILVKALTNPDFNLCLYLLQEQLLEEARYQEFWELSMEAVGFDTAIRKG--------------------------------------------------------- Hisca1 RPQHIILNGLDRYNPETTTIFQEYVVQQCETFDCYANLALLKLYQFNPHTETTTNILAKALTSPAFSLALALLPATLLESAQYTLFWSLVADVAGFEELVRVRIAVEVGKAFREIGQWLDLNG-LEALEKFV-VDIRVPKNKENEAR-GEIKGEKVGIEM Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 RTELILVSGVDRYNPSNVSILEDYLYHQIREYDCLANLAILKLYQFNPNPDVVINILLKALTLPDFNLCIALLDEDLLYRCRFPAFWKYTVEVVGFENAVRAVAVRAVKAAFTRISSYLDLNG--PNLEAYL-HDVVIPPNPDNQIE-ATVVQESIKLPQ Lenti61 RPPLILVSGVDRYNPSNVSILEDYLYHQIREYDCLANLAILKLYQFNPNPDVVINILIKALTFPDFNLCISLLDEALLHQCRFPAFWAYTVECVGFEDAVREVAVRAVKAAFTSIGTYLDLSK--DDLKAYV-EKVSIPPNPDNQIE-STVVQENIQLPR Malgl1 MP--------DRYSPQSRDILLQYLENQLETNDILANLAILKLFQLNPSLDTAVLILIKALTFPDFHLCISLLGEELLFQTKFVQFWNYTSKVAHFEDDIRKVALYSVKGAFRTISGYLHLEG--EALARFI-ENVAVPPNPDNEVK-STVVREEVSLER Mellp23 RPKQILILGVERYDPTQVQVLEDYLASQFNFYDPLANLATLKLYQFNPHDSVTVKILLLSIADSDFSLGLSMCGDSTLQSRKFNLFWSLISIIKDFDGLIRRSISQSVSSCFRSISSYLGLND-DQEVKDWI-KEAKIPDNSDNRPV-TTVTRENTTLED Mnele QFEQMSMEGLGRLNPEKLDFYVDYLKFQVEFYDGDANLNILKLYQFSPSIDNVHLVLTKALMNSDYVYCRAQLSQTLLETCQFPEFWNKIFEMTGFVEAARRFICHVVRLTYKNIEQLLGPMEDKSEFMDIV-AESVFVGHKEEMVE-QKEIIEKMPIEV Monbr LEERFIIGTIERYNPSNLGFFAEYFEKTLEYYDLDVCLAILKLYQFNPNLPTACTVLLKALTDNDFFLCASLLTVQLLESCRFAEFWVLFVTVVGFVETIREYAAYIIQSTYQHVSEMTNIKD-AAALEEFA-KSVS---RKDDVVV-SKTVVEKIEFGG Morel2 RPEVILIDGVDRYNPDNVSILEEYLATQCSEVDVMANLAILKLYQFNPNDQVVNNILVKALTEPDFNLCLYLLNEDLIEQARFKDFWNLTAEVLGFEDSIRKNVAKAVAMTFQSIEGYLHLKN--QAFSDFV-KAVSIPINKDNEAK-TTVLTENIKFEQ Mucci2 RPDNIMINGVERYNPENVNVLEEYLSKQCEEYDLEANLAILKLYQFNPKEPVIVKILVKALTAPDFNLCLYLLAEQLLEQARYAKFWQWTAVVPSFETEIRLVIARVMAMSYQTINANLGLTG--DAFDKFC-QDVQIPINKDNEAK-AVVIRENIKF-- Mydma KEDSVLLKGIDRYNPENLPTLEHYVQMQAFTYNLDANLAVLKLYQFNPKETVTCQILLKSLMHTDFVLCKCLIIENLLETCEFQQFWALIEGITGFKESIRSFIVSVLQITYESIAQLLGFPT-ETEFSDLL-KE-VLIANQEAHIK-SKNISEKITFDN Neucr2 RPDFIIINGLERYNPEAAGTLEAYLTQQCEFCDCNANRALLKLYQLNPKDEVITNILVKAMTSPQFDLALHLL--AQLEGAEYARFWALTTDIAGFEDMIRVRIAQLVGQSYREIQSWLGLNN-SEATTQFI-TEVQIPKNADNEAR-KAEIREDVNVDM Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RPAHIILNGLDRYNPETTTVFQDYVALQCETFDCYANLALLKLFQFNPQPDTVTNILAKALTSPAFSLCLALLPTTLLESAQYAQFWSLTADVAGFEELVRIRIAVEVGNTFRSITSWLDVRS-RDALNKFV-VDIRVPTNKENEAR-SEVKSEHVGIEQ Phybl2 RPQTILIDGVERYNPENVNVLEEYLATQCKDYDLMANLAILKLYQFNPSTNVIINILAKALTAPDFNLCLYLLSEQLLEQSRYAKFWELTAAVVGFEAAIRQVIARVVAMSHQVISSYLALSG--DELTKFC-NEVQIPINEDNEAK-AVVVIENIKFEQ Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 RTELILVSGVDRYNPSNVGILEDYLYHQIREYDCLANLAILKLYQFNANADVVINILLKALTFPDFNLCISLLDETLLQQCRFPTFWSYTVECVGFEDAVRDVVVRAVKAAFTRIGSYLNLSG--PELEAYG-AKYTIPPNPDNQIE-STVVQESIKLQQ Polpo KMELIIIA--DSYNINIAQKLEQFLDIQINIYHFQANSTLLKLYQFNPNKDYIAKMLAKALMSNDFLFLSYMIPFNLLETCKFKEAWEFFSVIPSFVDSVRNFVSNVLSITYQTITELLNIQQGG--LDEFM-STVSLQSDSVKQKK-----SDIFTFDR Pucgr2 RPEAILILGVERYDPTQVQVLEDYLTQQCNFYDPLANFATLKLYQFNPHDSITIKILLLSIVDSDFNLCLSLCGDRTLQTRQFIKFWAVVGSIGQFADLVRRSIGRSVASCFRSIDAYLNLTD-PALLQKWI-ETVIIPNNSDNCPV-TLVIRENTTIDD Punst1 RTEVILVSGVDRYNPSNVSILEDYLYHQIREYDCLANLAILKLYQFNPNADVVVNILLKSLSHPDFHLALALLDDTFLKQCRFPAFWEYTVEFVGFEDAIREVVLRAVKAAFKRISLYLDLEG--ADYEAFL-SKVTIPVNPDNQIS-STVVQEDIKLPQ Rhior3 RPENIVINGVERYNPENLETLEGYLNQQCEQYDCEANLAILKLYQFNPKESVIVKILVKALTAPDFSLCLYLLTEQHLEQARYTKFWQWTSVIPNFEIEIRKVIARIIAMSYQTVSGYLGLSG--DAFDKFC-ASVQIPINKDNEAK-TVVIRENIKFEQ Rhoto1 RPAHILISSVDRYNPSNVHLLEDYLQSQLSQYDLLANLALLKLYQFNPSPSASLSVLFLALASPDFSLAWSLLSDKLMQARKFRDFWRLARSAPAFDGRVRESIAREVERSFRSIAAFLGTTD-ASQLEQLA-KQIQVPQNDSNTPK-AVVTHERIEIEQ Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -MDEVLLETFEQYDNVHLPRLVQTLHATIEDFDLDIANAILRLYRFYPDADTAASILMGALMENDFTLCLSLLHPELLETCDFVEFWALTCHLSDFKTSILEYIAHIVTATYQTIP--------KSTIEKLT---------------------------- Schco3 RTELILVSGVDRYNPSNVGILEDYLYHQIREYDCMANLAILKLYQFNPNPDVVVNVLLKALTGPDFNLCISLLDEDFLYRCRFPAFWKYTVECVGFEDAIREVAIRAVKATFTKISTYLDLSG--AELDAYV-EKVAVPPNPDNHIE-ATVVQESIKLPQ Schpo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma RPDFIIISGLERYNPEAAGTLEAYLTQQCEFCDCNANRALLKLYQLNPKDEVITNILVKAMTSPQFDLSLHLL--AQLEGAEYARFWALTTDIAGFEDMIRVRIAQLVGQSYREIQSWLGLNN-AEATTQFI-TEVQIPKNAENEAR-KAEIREDVNVDM Sphar VDD-IVLATLDRFNPDILPVLHKYIQ----EYNLEANIAALKIYQFNPDRNMTLTILLKSIMGSDFHLCQCLMSE------------------------------------------------------------CMYVLN------------------- Spipu1 RPEDIIVETVDRYNPQNIPVLESYVEEQMEVYDRDACLAVLKLYQFNPNIEVVTNILGLALGDPDFNLCLYMLNEHLLEQAKFQEFWALVAKYLHFDRRIREYASVTVGIAYQAIEEYLALEG--VDLDQWI-AEVNLPISKENQAR-PVIVQESIKFEQ Sporo1 RPEHILISGVDRYNPSNVHLLEDYLQQQLAQYDLLANLALLKLYQFNPSPPAALSILFLSLSAADFGLAWSLLSDSLLHGRKFRQFWSLKRDAKGWERAIRQEIAKEIELSFRSVKGFLGTQD----FNEIA-ESVQLPQNDSNTPK-SSVTHERIEIEH Stehi1 RPELILVSGVDRYNPSNVGILEDYLYHQIREYDCLANLAILKLYQFNQNPDVIINILVKALTFPDFNLSIALLDDSLLQQCRFPAFWAYTVEVVGFEDSIREVVVRSVKAAFQRIGTYLSLSD--SGLDEYI-SKVEIPPNPDNKIV-STVVQENINLPQ Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr MSTSVLLKPASRFDVNSLPAMEKIVREHVAEYNVELNLAVLKLYQFNPNEEIISLVLAKAMMAPDFQLALYLIPENLLDTAKFRAFWDLLGSIAGFGDAIRGFAASVVSSTFQLIDDLLFLDQ--AAAAAYA-EKVSIPLNEFNQAK-AKEIKEDIRFEQ Treme1 RTDVILIHGVDRYNPSNLSFMEDYLASQVQSYDLLANLAILKLYQFNPNPDVIINILLKSLSGSDFNLSMSLLREDLIRNCRFAAFWSYLPQHPHLIPTLRVRFATSIASSFSRISRWLDLSE--SDINDWC-AS--IPKNGDNDVK-AGVVRENVELSQ Trire2 RPDYIVINGLERYNPEAVGTLETYLQEQCEFSDCNANRTLLKLYQLNPKDEVVTNILVKAMTSSQFTLALHLI--SQLQGAQYADFWALIADISGFEDLVRERIASLVAQAFREIQSWLGVN--EDKTRKFI-TEVKIPSNPDNEAK-KSEIREDVNVDQ Umbra1 RPEVILIDGVDRYNPDNISILEEYLATQCQEYDLMANLAALKLYQFNPNDRVIINILAKALTAPDFNLCLYLLTEQLLEQSRYAKFWELVSEVRGFSRAIRSIVARVVSMTHQQIASYLDLSG--DDFAAFV-KEVQIPVNKDNEAK-TVVIRENIKFEQ Ustma22 RPQHILISGVDRYNPQNLDVLHDYLAQQLDSYDLLANLAILKLYQFNPNYVVVINILLKALVLPDFNLCISLLGETLLFQARFREFWSYAAKISEFENAARRVALNSVKGSFTSISNYLNLSG--SQLAEFI-NAVSVPANPDNEIK-ATVIREEISLDQ Walse1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2929.fasta_al_trimmed; alignment length = 66] Allma1 IKELRISAGL-RSFIAKSYPAMK-QANPSLPILIREAQN-VEARAFARYDFGVERLENVAEIAAKI Ashgo11 ------------------------------------------------------------------ Aspfu1 LKELRFSAAT-RSFLQRAYPTMK-KHNPQTPILIREAAG-TLPRVYARYGFGKEKLSGLSQIEEKV Aurde31 VKELRFSAGARRQYITSQYASIK-KANPDLPVLIREANG-TPARVFARFERGVERVDGLSEVDKAL Batde5 IKELRISNGI-RDFILSNYKSIK-AANPHLPVLIREAPG-TEARAIARYAFGAERLENLTQVETQF Botbo1 LREIRVSAGT-RQFIQTAYPAIK-KQNPDLPVLIREAQG-TPARVFARFERGVERLDNLSDVERKV Botci1 LKEVRFSDAT-RSFLARTYPTMK-KHNPNTPIMLREAAG-TQPKVYARFEFGREVLAGLSEIEDKV Caeel LREIRISAGV-RAFIENDYVGIK-KANPQFPILIREASG-IVPRVFARYEHGVERLEDLSNVKSTI Canalb1 LKELRFSIPV-RNFLTKNYPSLKTQSNYKLPILIRESYG-IPPTLTARFERGEEVLEGLDGVEKAL Cangl ------------------------------------------------------------------ Capow VRELRISQGA-RDFVTKQYAELK-QAHPTLPILVREAAG-IEPRVYARYAFGQEALSNLTQVLDSI Catan2 IKELRISAGV-RSFLSKSYPDIK-KANPTLPILIREARG-TEARAFARYDMGVERLEGLDRIADKL Cioin -----LSQGV-RDFVEQHYVSVK-TANPKFPIMIRECSQ-VEPKIYARY----------------- CocheC53 LKELRFSAAT-RNFLTRSYPAMK-KANPSIPIMIREASG-TEPTVFARFDFGKERLKGLDAIEQQV Coere1 LKELRISRGLRRDFIIKTYPDLK-KANPGLPILIREAAG-VESRIIARFDQGRERVDNFNDVEQKF Conco1 LKELRISQGL-RNFVINNYKQIK-QANPNLPILVREAEG-VEARVFARYDKGQETLENIPQVPSKI Conpu1 LREIRISEGT-RQFIVSQYPSIK-QANPDLPIMIREASG-TPARVFARFERGVEKLEGLSDVAKRI Copci VREVRISSGT-REFILANYPVIK-QNNQDLPVLIREAEG-TPARAFARFERGVEKLENLPQVASRI Croqu1 VREIRFSKPM-IEFIKTAYPPIK-AANPTLPFLIRPATH-TPSRAFIRFERGLETLDTLESIEDSL CryneH991 VKEIRLSAGV-RQFVQSSYPAVK-SANPDLKFLIREASN-ISPRAFVRFERGVESLANLSDVGKVL Crypa2 LKEVRFSAAT-RAFLTRTYPTMK-KHNPSTPIMLREAQG-TQPKVYARYEFGKEELEGLSQIEDTV Debha1 LRELRFSIPL-RKFLTANYPSLKTQLNYKLPILIRESYG-IPPSITARFEKGMEIVEGLDGIEGIF Dekbr2 IHELRFSKTL-KSFLVKSYKPLK-AANPDLPILIRECSG-VEPMLVMRLDKGVEILKDLSEITNLL Dicdi LQEIRISEGL-RNFVVKNYSDLK-RLNPKLPLLIREGHG-VEPVIYARYDWGKEEVTNLTEVEEKL Dmel LKELRISKGV-REYVERFYPNLK-KSNPDLPILVRECSG-VQPRLYARYGNGKEVLANHADIHKNL Enthi ------------------------------------------------------------------ Falba LHELRFSAGV-REFISNTYPKIK-AANPTLPVLVRPGGEATPARVFARFENGAEIIDGASAIHSSM Fomme1 IREIRLSAGI-RQFIQTAYPTLK-QHNPHLPVLIREASG-TPARAFARFEYGVEKLDNLSDVEQKI Fusgr1 LREVRFSAAL-RSFITRSYPTMK-RNNPNIPILIREAAG-TQPKIFARYERGVEKLEGLSEIEDTV Galma1 LREIRISEGT-RQFILSKYPTIK-KHNPELPVLIREATG-TPARVFARFERGVEKLDNLPEVEMKI Ganpr1 IQELRVSAGL-RNFILNNYPALK-SANPELPILVREAQG-VEARLFARYGFGVEKVEGLPEIEVKL Gloin1 LKELRVSSGV-REFISKNYVSLK-EANPNFPILIREASG-VEARFFARYDFGKEELNNLPDVESEL Hisca1 LKELRFSDAT-RAFLKRAYPTMK-KNNPFIPIMMREALD-TEPRVFARY--------GLTEIEEKV Klula1 ------------------------------------------------------------------ Lacbi2 LREIRISAGT-RQFIVSKYPTIK-QHNPDLPVLIREATG-TPARVFARFERGVEKLDNLSDVETKV Lenti61 VREIRISAGA-RQFITSHYPTLK-QHNPDLPILIRQAKG-TPARVFARFDKGLEKVEGLSDVASRI Malgl1 ------------------------------------------------------------------ Mellp23 VKEIRFFKPM-NDFIKQTYPKIK-SSNPNLPILIRPLNSISEPRCFVRLENGVEKLNLFKEIESNL Mnele LREVRISAGA-RQFVSEHYVNLK-VENPTTPILIRECSD-VQPMLYARFAHGREKLNDMVEILEKL Monbr ------------------------------------------------------------------ Morel2 LKELRVSNGI-RQFVASNYTAVK-AANPNLPILIREAKG-AEAKIFARFEHGQEKLDGLSEIEQKL Mucci2 LKELRLSSGL-RDFVAKNYVDIK-KVNPELPILVREASG-IEARAFARFDKGIERLNNASDIENTL Mydma ------------------------------------------------------------------ Neucr2 LKEVRFSAAT-RSFLLRNYPAMK-KDNPATPILIRDASG-TLPKVYARFEFGKEKLEGLSQIEETV Orpsp11 ------------------------------------------------------------------ Pench1 LKELRFSAAT-RSFLNRAYPTMK-KHNPQTPIMMREASG-TLPRVYARYAFGKEKLSGLSQIEERI Phybl2 LKELRVSSGL-RDFIAKNYSSIK-SANPNLPILIREASG-AEARIFARFDKGIEQFQNKAEIEKTL Picst3 LKELRFSVPL-RKFLSVNYETLKVQSNYKLPILIRESYG-VPPSLTARFEKGKEVLEGLDGIAKTL Plicr1 LREIRISAGT-RQFILSKYPIIK-KHNPDLPVLIREATD-TPARVFARYERGVEKLDNLSDVESKV Polpo LQEIRISEGL-RNFITKNYTDLK-KLNPKLPLMVREGHG-IEPVIYARYDWGQEEVTNLSEVEEKL Pucgr2 VREIRL---V-KSFIQSNYSSIK-SSNPDLPFLFRESSIGTPARAIVRFEYGIEKLEQAKEIESLL Punst1 IRELRISEGT-RQFIQSAYPAIK-KANPDLPVLIREASG-TPARFFARFEKGVEKLDGLSDVEARV Rhior3 LKELRLSSGL-RDFVAKNYLSIK-QANPELPILVREASG-VEARAFARFDKGLERLQNASDIEKTL Rhoto1 VRELRLSEGV-RAFIRSSYPQIK-SANPDLPILIREASG-TPARGFVRFERGVEKLEGASEVEKKI Rozal11 ------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------ Salro VRELRISQGA-RDFVTKYYSSLK-KANPSLPVLVRECNG-AQAQVQARLPFGEEKVNGMSEIKSVI Schco3 LREIRISAGT-RQFIQNNYLTIK-QHNPDLPVLIREATG-TPARVFARFEKGQEKLENVPDVESQI Schpo1 ------------------------------------------------------------------ Sorma LKEVRFSAAT-RSFLLRNYPAMK-KDNPATPILIRDASG-TPPKIYARFEFGKEKLEGLSQIEETV Sphar ------------EFIERDYVAIK-KANPNFPILVRETSA-IDPKVFARYGFGVEKLSGMSEVAKTI Spipu1 LKELRISKGT-RDFILKQYSAIK-DANPTLPILIREASG-IEARAFGRYALGQERLENLSEVEARI Sporo1 VRELRVSEGV-RQFIKSSYPSIK-QANPEVPILIREAFG-TPARGFVRFERGVEKLEGVSEVEKKI Stehi1 LREVRISAGT-RQFIQTNYSTIK-QHNPDLPILIREAKD-TPARAFARYELGVEKLDGLSDVESKI Tapde11 ------------------------------------------------------------------ Thetr VREVRFSEPM-RNYVASNYVALK-KANPEVPLLVRPAPG-VSPHIVLRLPKGVETLADAADIADRL Treme1 VKEIRLSQGV-RQFILSSYSGIK-ASNPDLKFLIREAAG-VEPKAFVRWERGVESLSGLNDVASAL Trire2 LKEVRFSAAV-RSFLTKQYPAIK-KANPNTPILLREAAG-TLPKVYARFEFGNEKLEGLTQIEDTV Umbra1 IKEVRVSKGL-KQFVAENYTGIK-QANPNLPFLIREANG-VQPRIFARFDKGVERLENASDVKNAL Ustma22 LKEVRLSAGA-RKFLEANYKPIK-QSNPDLPFLVREASG-TPARAFARFERGVEKLDGLSDVEKKF Walse1 IKEIRLSEGLSRQFIKSSYPALK-QSNPHLPILVREASG-APARAFARFEYGLEKLEGLSEVTKQI Zygro1 ------------------------------------------------------------------ [Cluster2946.fasta_al_trimmed; alignment length = 170] Allma1 ---LDEDLYVEALSEIIQRDFYPDLDRLRAESPDALASRDARQRLLRLDAFLARYTSEDNAAFHALLEQERQEVR-RKLKWMFDAEEPTWEYSVHNQFMFPPSE----IPTP-VPHGATA-----DIPGAI-EATPRYHVPDTPKRDALGIVLSDRAR------AAAARA Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ATVLDEDVYTNALSEIIARDYFPGLLEERVKQEDALESKDSKKKLLGLMAFQAKYTSEDNESFNKLLDKQNAKRQ-EKYAWLWSGNKDTWKSRPENSLMFMPSSAIAGRPTP-RVNGYAFVEDEPEPDGAS-DSAPPFSIRENCKREELHHRMVDRVARTKRAEAAQKLL Aurde31 QEVLDEDEYTAALSKIIARDFFPSLVHLESTNEDAVQAQDSVRRLLSLDAFQARYTSEDNSSFTQILDEDNRQRR-EKYKWAWAAENDGWVFKNRNALMFPPDAAIAGTPGP-QVRGFSLVAVPSINAGTL-DATPPFHLRAPSHREQLATRLSSTAAKSLREKAAKRLL Batde5 AASLEEDEYIAGVSTIIERDFFPNLRKLRVQNDDAVQNANLSSQLISLDKFQTKYTSEDNASFLNILELQNEAKR-EQYHWLYDKEKDEWKFKAKNTLMYYPDGATPGLFSP-RVSGYGFVTTPTFTPGMI-EGTPSFKIPATPRREEISMRLSEKASKALKRRAAQTLL Botbo1 QVILDEDEYTSALSTIIARDFFPSLSHLDATNSSALDSQDSVRRLLSLDAFQAQYTSEDNASFTEILDEENRKRK-EAWGWAWEAQKPGWSFKARNGLMFPPDAAIAGEP-P-RVSGFGFVAVPSPSPGTL-QGTPPFHIAPPKARDVLGRKLGQNAGKSLSARAARSLF Botci1 KNVIDEDAYTDAISEIIARDFFPGLLETETKQEDALDSKDAERRLMSLTKFQSLYTSEDNESFYKLIDKQNQKRA-EKYAWMWTGNKDSWKSKPNNGLMFRPDSAIAGKRTP-RVNGYSFVDEPEEE-GPG-ETTKPFIIKEQSKREDLHYRIVDKTARSKRTSAAERLW Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow GRVLDEDAYLSALESIIQRDFFPHLSKLRAQHEQALERKDLLRAILSLDEFLATHTSEDNASFAEIMERTQKRNR-EKYAWMYKGASARWKYTPKNTLMFPVDG--AEAPTP-RVGGHSF-STPTPVPGMI-DGTPTYSLPEVRPREQIAIGLADKSSL-----AAQRFA Catan2 ---LDEDEYTAALSRIIKRDFFPDLDRLRAEAHDALDSHDAKDRL--LDQFLEKFTSEDNASFAELLADHNARVRQRALKYFPPPDHPTWAYKPHNALMFPPTSTTTAAPTP-RPHGDVA-----SMPGAI-DATPRYRIPDTPARDMLAM----RMA------VARKLL Cioin KKVLDEETYTEKVEEIISRDFFPDHERLKDEKEEAEEKEDIALKYVTLDQFLVKYTSEDNESFERIMDKTDEARR-AKHKWLYDAEVHTWKYKNKNHLMYYPEGGHDGKSSP-RVGGYGFVATPSPMPGEI-GGTPAFRFPDESERDRLTHKMVDDNTKKQRAKAARRL- CocheC53 SVVLDEDTYVSAISHIIRRDFFPGLAEADAQRENAVESKNAGKKLMSLGAFQAKYTSEDQESFSQIVDKQNKARF-EKNVWLRQGNMTGHRHTAINSLMFGPESAIAGRPTP-RVNGYAFVAHPPSDDLNT-NTKAPFTMHESSSREKMLHRMVDKINANRTSSAAQRLF Coere1 AVVLEEDEFRATVDAIVARDFFPDLYHT-----------------ESLDEFLRKNISDDNASFSSLLRDENAQRQ-AKH-----KKV-------RNALMFAPD-------TP-EIGGYKMV-------G--------FEIKPATPRELTGQQLA---KPKQ---AARRLL Conco1 KIVLTEEIYTLCLSYIIERDFYSNLNQLQDKLSIPFDKGDVNFLLLNLDTFLSIYTSEDNQSYEKIVEKYELKRN------------EGWKHKAQNSLMLLPDT---------YLCHLKLI---------------TYHM------------------------------ Conpu1 QEVLEEDEYTAALSRIIARDFFPSLIHLDATNEDAISSQDSVRRLMSLDSFQTKYTSEDNASFTQILDDENRKRR-EMWGWAWEAQKDGWKFKTRNSLMFPPDAAITGTP-P-QINNFSLVTMPSLSAGTL-SATPPFHLSAPSNREALSHRLSAQASKNLRAKAARRLL Copci QVVLEEDEYTAALDKIIARDFFPSLVHLDATNEDAISSKDTVQRLMSLDAFQAKYTSEDNSSFTQILDEENRQRK-EKYGWAWEAQRDSWKFKARNSLMFAPDAAIAGTP-P-KENGFSLVNLPSPTPGTL-NATPPFHIPKVSRREALAQQLSTKASRSLREKAAKRLL Croqu1 QKVLEEDEYMEALSAIIKRDFFPSLDQFDKEREKNLHLTAADTVALSLDDFCARYTSEDNSSFSEILNNANQLKR-LKYTWAFDSSSNAWPHVTRNALMFAPDAAINGTTSP-KVNGFGFVAMPTPNPGEI-IATPPFKIPKTPRREELAMGMARKASKSLREKAAKLLL CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 KKVIDEETYTDALSKIIARDFFPGLLESETQQEDALESKDAGRRLMSLGAFQAKYTSEDNESFYKLLDKQNQKRA-GKYGWLWRGNKDTWKAAPMNALMFAPDGAIAGRPTP-RVNGYAFVDEEEEPVGPG-DATPPFKIQDQRKREGLHHRMVDRIAQSKRTSAAQRLW Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi YRVINEEKYVDSLNKIIVRDFFPDLPNLRDQLEEAVETNDTVRRQTNLDNFVNTFVSEDDASYIDIQKKQNERIL-IKYKWLFDKAKDTWNYKVRNTLMFKPENSNNNKPSSMEIENSTFGSTPQIIPGRV-DGTPSFKIPETPKREQLANKLFEKVAVSKTKSAAQRLL Dmel PKILTEEKYIEEMSKIIQRDFFPDLERLRAQNDDAESRRDIRERYLSLDAFLQKYTSEDNQSFQEIIETAEAKLR-QKYAVLYNHEKETWNYTNMNSIMYVPDGPQNGAGTP-KVRGFDLLRSPSPRPGEI-DGTPSFRINENSRRENIAIALAERVSERMRNQAAQLL- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 QVVLDEDEYTEALSHIIARDFFPSLVHLDATNNDALRTEDSVRQLMSLDSFQAKYTSEDNSSFTQILEDENRVRR-EKYGWAWDAQRDGWKFKTRNAFMFPPDAAIMGTP-P-TNNGFSLLSVPSPTPGTL-NATPPFHLPPPTSRETIGHKLSNKAVKSLRAKAAKRLL Fusgr1 KKVLDEDTYTETLSQIIARDFFPGLLQTETQQEDALESKDAGRRLMSLSKFQETYTSEDNESFYKLVDKQNQKKA-EKYAWLWRGNKDTWISNPKNNLMFRSDGAIAGRPTP-RVNGYAFVDEDDEDEGPG-DDSPPFRLQEQRDRETLHERMVDRIAQSKKESAAQRLW Galma1 QVVLEEEEYTEALSRIIARDFFPSLVHLDATNEDALQTRDSVRRLMTLDEFQARYTSEDNSSFTEILDEENRVRK-ERWGWAWNAQEDGWKFKARNSLMFPPDAAISGTP-P-NERGFSLVNLPSPTPGTL-NSTPPFHIPDISTREAISHKLSDNASKSLRAKAARRLL Ganpr1 KTVLDEDTYISGLAHVIQRDYFPDLGKMRASAEDAVESGDATLELLPLSSYQAVYTSEDNASFAVQVDKENERKR-EKFAWAYNAEHPAG----------PPPE--TLAPTP-GLFGPSATVAPSDVPGDI-EATPRFSMAPTPRREELAANLGRKAG------AARTLL Gloin1 QEILDEDSYTEALSEIIKRDFFPSLLTLEAQNDDAWNTNNATRKLMSLDSFQSKYTSEDNASFSELMKKASEQQR-EKHKWMYEKEDASWKYKVRNSLMFYPEGAASGIDTP-TVGGYSFVATPSPNPGMI-EGTPSFQLPPTQRREIIGMNLSNNASRNIRKR------ Hisca1 ATVLDEDEYTDALSHIIARDFFPGLLETQTQREDALESRDAGKNLMSLSMFQSKYTSEDNESFNKLLDKQNVKKR-QKYAWMWNGNKDAWASKPENSLMFIPSSAIAGHPTP-RVNGFAFVEDEPTPQTSS-SATPPFTIRENRRRELLHHRMVERVATIKRAEAAQRLW Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 QLVLDEDEYTAALSKIIARDFFPSLVHLDATNDDALHSQDSVLRLLSLDAFQARYTSEDNSSFTQILDEENRTRK-EKWGWAWEAQRDGWTFKARNSLMFPPDAAITGTP-P-TAKGFPLVTLPSPTPGTL-DATPPFHLPEISSREAISHRLSNNASKSLRAKAARRLL Lenti61 QVVLEEDEYTEALSHIIARDFFPSLVHLDATNNDALRSEDSVRRLMSLDAFQARYTSEDNSSFTQILEDENRRRK-EKYGWAWDAQRDGWKFKARNALMFPPDSAIAGTP-P-TNDIHSLVSIPSPTPGTL-NATPPFRIAEPSSRERLSHKLSSDAAKSLRTKAAQRLL Malgl1 QTVLDEETYTRGLSQIIQRDFFPDLPRLRAQNAHALEEGDCARALMSMDEYQTRYTTEDNASFAQLMDLDRKRRR-DKYQWAYDAAHAR-------------TS--LDRATP-RIHGYNF-SA-TSTPGQL-AATPSSVMTDVTP-------LASQTP------AARSLL Mellp23 QRVLEEDEYIEALSSIIKRDFFPSLDQFDKERQTLLQSTNTDRQILSLDDFCARYTSEDNSSFSEILNNANQLKR-LKYTWAFESSNNAWPHVTRNALMFAPDAAINGTPSP-RVNGFGFVSMPTPNAGEI-MSTPPFKIPKTPRREELAMGMARQASKSLREKAGKRLL Mnele RIILDEEKYVECLDHIIERDFFPDLKKLRRDTG-------ERVDLSNLDSFLNKHTSEDNASYSEIVEEEVAKNK-EKANSLYAP--DGWNFKRKNELLFPPEGGVDGKPTP-RVKGYAYCATPQIEPGEV-ESTPAFKIPQVPEKDRLGHALADRVNKRHKQRAARRLA Monbr KTVLEEDDYVAALEKIIERDFYPQLPQLRAQEEQALEANDISRRYLSLDRFLDKYTSEDNDSFDQIIEQTNLRLR-AQFESLFGRAEDHWRHTPRNQLMWAPSE-DDGNKTP-AVNGYKFVATPSPVPGEI-DGTPAFNIPEPSARDQLGRRLAEDTAAKRRKMAAQQL- Morel2 QVILEEDDYIEALSKIIERDFFPDLARLKRQHADAVEQNDAARELLSLDQFQMRYTSEDNASFNEIIEKINAQKK-EKYKWLYEQEKSTWEYKAKNSLMYAPEG-----PTP-KVAGFSFVSTPSPSMGTI-EDEPPFKLPPTPRRELIAQKLSEKASKSFRAGAARSLL Mucci2 PVVLDEDTYTEAISLIIERDFFPKLAKMRAQQNEAQSHGSAGKALLSLDQFQTLYTSEDNASFTDLLERANIKVK-EQNKWFFDR--SGWKYKARNALMYFPQ-NGALTPSP-HIRGYHLVATPALSPGSI-EGTPQFSLPQVSKREELGMKLSEKASKAYRKKAAQHLL Mydma QKILDEEEYLTILEKIVERDFYPELTKLKLRLHNALETDDIQLQLLSLDSFLLKNTSEDNASFEKIMEITRKKHR-EKYAWLFEKQEETWKYVPRNALMYTPDGGVDGH-TP-TVQGYGFVATPSPAPGEI-EGTPSFKIPEPPRREMLAHSLAEKASKQHREKAAQKLL Neucr2 KRVIDEDSYTDALSHIIARDFFPGLQQAESQREDALESKDATQRLMSLGAFQARYTSEDNESFYKLLDKQNQKRA-EKYAWLWNGNKAHWKAKPNNELMFAPEGAIAGNRTP-RINGYAFVDEEPEPQGPG-DATPPFHLQEQRKKEALHHRMVERISQSKRTSAAQRLW Orpsp11 ---------------------------------------------LSVDAYQNKYTSEDNDSFNEIIAKNNELKK-VRNEKLYGQEKETWKYKTQNSLMFIPDSMISSTPSE-GTSGYKMVSTPSPNPGSI-EGTPVFKIPETPRRELIGIKLSEKASSNMRKRAAKNLL Pench1 ATVLDEDVYTNTLSHIIARDFFPGLLETQIKQEEALESKDSKKKLMGLVAFQAKYTSEDNESFNKVLDKQNEKRR-EKYPWLWSGNKNSWKSRPDNTLMFLPSSAIAGRPTP-RVNGYAFVEDEPEPEGPT-SEKPPFQLGETRKREALHHRMVDRVARNKRAEAAQKLL Phybl2 PVVLDEDTYTEAISYIIERDFFPNLAKLKARQNQAQESGSAGKALLSLDQFQTLYTSEDNASFTDLLEKANAKRK-DKYKLIFDE--GTWKYMPRNALMYFAD-QGKMTPTP-EFRGFSLVATPSPTPGSI-EGTPQFSLPKASRREALGMRLSERASRAYRKKANTHSI Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 QVVLDEDEYTEALSRIIARDFFPSLVQLDATNDDAIRTHDSVRRLLSLDEFQARYTSEDNSSFTQILDEENRQRK-GKWAWAWEAQRDGWRFKNRNALMFSPDAAIAGTP-P--EGSFSLVNLPSPTPGTL-NGTPPFHIPAPSARESISHKLSARASKSLRAKAARRLL Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 QKVLEEDEYMEALSKIIKRDFFPSLDQFERQKQNLLHSPSTNSNLLSLDEFCSRYTSEDNSSFSEILNNANRLKR-IKYAWAFDSSTDSWPHVTRNALMFSPDAAINGTPSP-KVNGFSFVELPTPDPGEI-MTTPPFRICKRPRREELAIGMARQASKSLRQKASSL-- Punst1 QEVLDEDEYTAALSRIIARDFFPSLVHLDATNHDAMSSQNSVRRLLSLDAFQARYTSEDNSSFTQILEDENRKRR-EKWAWAWDAQRDGWKFKTRNALMFPPDAAIAGTP-P-TINNFSLVAMPSPTPGSL-NATPPFHISGPSAREQLSHKLSSKAAKSLKAKAAKRLL Rhior3 PVILDEDTYTEAISFIIERDFFPNLAKMKAQQNEAQQSGT-----LSLDQFQTLYTSEDNASFTDILEKANQKAK-EKNKWFFDK--MGWKYKARNALMYYPE-KGNLTPSP-SLRGYQLVSTPRLSPGSI-EGTPRFSLPKISRREELGMKLSERASRAYRKKAAQHLL Rhoto1 QEVLPEDEYIEHLSAIIKRDFFPHLQTLETRNEAALESEDSVRRMLSLDAFQSRYTSEDNSSFQDLLVVDNEQRR-DKHAWAWHAEKSAWPFKNRNSLMFPPDAAIAGTPTP-RVSGFSFVALPSHSSGTI-EATPPFRVREADRREELAHKMARKAKRSLAGSAARSLL Rozal11 KKVLEEEEYTEAIASIIQRDFFPDLQKLKSQVSEAIENSDEAVKIMRLDAFLSRYTSEDNASFGDILEKINEERR-RINPWAFKD--EYWPSKGKNSLMFSPTGRITYTPNPMNVGGYGFVSTPLIRPGTI-EGTPRFRMPETPLREHIKDELVSRASKNYMRKAAQSLS Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 QIVLEEDEYTAALSHIIARDFFPSLHHLDATNDSAVESGDTVRRLLSLDEFQARFTSEDNSSFTRILDDENEKRR-EAHGWAFEAQRQAWRFKARNQLMFPPDAAIMGTALN-SSDSFNLVNLPTPTPGTL-AGTPPFRIAEPTQREVISRKLSQSASKSIRERAARRLL Schpo1 PIPLEEDDYIEGLSYIIQQQYFPEVGSFDAQNEIAKNSED--RK----NKF----TSEDNASFGELMEDESR------------LRAKTWNYQPKNALMYTPE-STALNSSP-SASRHTALSIPK-------TPTP------------------------------KRV- Sorma KRVIDEDSYTDAISHIIARDFFPGLQQAESQREDALESKDATQRLMRLGAFQAKYTSEDNESFYKLLDKQNQKRA-EKYAWLWNENKAHWKAKPHNELMFAPEGAIAGNRTP-RINGYAFVDEEPEPSGPG-DATPPFHLQEQRKKEALHHRMVERISQSKRTSAAQRLW Sphar NKILDEEEYNEGIDAIIEREFFPQVGRLRAENEDAKAENDIARKATGLNEFLRTHASEDNAEFEVLMAKQREANK-QKYAWLHAVEAIGWDYKNKNSLMYFPDGGTVLGSSP-EVRGYGFIPVPRPGEGSI-EDTP----------------------------FYQRVL Spipu1 PDVLEEDTYVESLSKIIQRDFFPHLKRIKLQNEDAVQNGELGDELMSLDAFQSRYTSEDNASFNNMITRINDDKR-KKYSWIYDKETQQWKYAAKNSLMYYPSVATPGLLSP-NVNGYSFVSTPVLNDGTV-EGTPGFSMPPTPRREIIGKKLAEKANKGKRPDAARHLL Sporo1 ----------------------------------------SNRKMLSLDAFQSKYTSEDNSSFATLLARDNELRK-DKTRWAWQAEIETWPFKNRNSLMFPPDAAISGTPTP-RVNDFSFVALPSPRAGSI-EATPPFRIEDTSKREILAHKMAKKAKRSLAESAARSLL Stehi1 QVILDEDEYTAALSQIIARDFFPSLVHLDATNDDALNSNDSVRRLLSLDAFQSRYTSEDNSSFTHILHEENKRRK-EKYGWAWEAQRDGWSFKTRNNFMFSPDAAIAGTP-P-GVNSFSYVSLPSPTPGTL-TGTPPFRINEPSARENLSHRLSNTAAKSLRAKAAKRLL Tapde11 AIVLEEDEYIDGLSEIIKRDFFPGLKKPELAEDESHQIPD-----VSLDEYQARYTSEDNASFLDILDTQNLSRR-DKYAWHYNDNKDGWKVTPKNALMFQPDA------ES-TVNGYGFIRNPFPEPGKVGEQTPPFKIAETPARDQLHDRLLLKARRASTPKAAHRML Thetr QTVLDEGTYQAGLANAVEAEFFPPLLRLRAQLAEAEDAGDIASRSLGVTRYLATYVSEDNAAFEE----------------------------LENGTARQSDD------GP-TVNGYSFVSAPQ-----------GYTLPPVRQRERAAAKIGARYAAARAQRALRSAL Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 KRVLEEDAYTEALSQIIARDFFPGLLETQIQQEDALESKDAGRRLLSLSAFQATYTSEDNESFYKLIDRQNQKRA-DKYAWLWRGNKEAWNAAPRNGLMFTPDGAIAGKPTP-RVNGYAFVDEDGDGAGPG--DATPFKIQDQRKRELLHERMVERISKSKSDSAAQRLW Umbra1 AIVLDEDTYTDAISYIIERDFFPNLAKLRAQQEHAEESGDAGRELLSLDQFQARYTSEDNASFIDLLGKANEQRK-EKHKWVWDK--GTWKYKARNALMYQPDVSGKMTPMP-EFGGYNLVESPSINPGEI-EGTPSFRLPQPSRREQLGHKLSERASKSYRTRAAQHLL Ustma22 QAILTEEEYTCALSSIIKRDFFPDLDRITAENEAAVEAEEALDRLLSLAHFQSRYTSEDNASFSQLLDRDNELRK-RKHAHLFAHEAHRWKYTARNALMFGADAGRAGSFTP-KVNGYGFV-TPYSTPNAIKRSRQGFQLPRLDKREQLAEKLTSTPKLKRAAEAAKALL Walse1 QIVLSEEAYTKALSDIIKRDFFPDLKKADDLSYAADEETD-----MSLEQFQSKFTSEDNASFSYLLHKANLKRR-ERYAWAYNAELDTWGFTATNNLMFNPDTAVNATSTP-HIGGYKFVSMPSPRAGTL-SGTPDFKIPKISRRDRLGHQLASHVKTKQTPAAGHALL Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2949.fasta_al_trimmed; alignment length = 65] Allma1 FP-----TPIKTAQRSCTVLPTFVGAKFLVHNG--KDYVPVNITEDMVGHKLGEFAVKFKDSQKK Ashgo11 VPLPIKEAPIRTNARSATVLPQFVGLKFQVHNG--KDYVAFEITEDMVGSKLGEFAFSYTQTKNK Aspfu1 ----------------------------------------------------------------- Aurde31 FP-NLREAPIFTRARSCTILPSFVGIRFHVHNG--KHFIPVNVSAEMVGHKLGEFSGKHPDPPDR Batde5 FP------AIKTQARSSTILPSHVGKKFLVHNG--KSYLPVFVTEQMVNKKLGEFAFSYKKKER- Botbo1 FP-NLQQAAIKTRARACTILPNFVGIKFQVYNG--KQYLPVTVTEEMIGHKLGEFSFTFRQTKNK Botci1 VPLPIVKPPIRTQARSATILPNFVGLTFEIHNG--KVYNEVTITEDMVGHKLGEFSFTYKQSKNK Caeel ----------------------------------------------------------------- Canalb1 VPLPVANAPIRTKARNCTIIPQFVGLKFEVHNG--KEYVELEVTDDMVGSKLGEFAFMYKYSKN- Cangl VPLPIKEAPIRTNARAATILPQFVGLKFEIHNG--KDYVPIEISEDMIGRKLGEFAFSYTQTKNK Capow ----------------------------------------------------------------- Catan2 FP-ELAGAPIKTDKRACVILPNFVGVQFQIHNG--KDYVPITVTEDMVGHKLGEFAVRFKDSQKK Cioin ----------------------------------------------------------------- CocheC53 VPLPIVQKPIKTQARSATILPNFVGLKFQIHNG--KSYLDITITEDMVGHKLGEFAFMYKQTKNK Coere1 FP-GLAESAIKTKMRSCTIMPHMVGARFMVHNG--KFYLPVRVTENMVGRKLGEFSFSYRMTKNK Conco1 FP-NLKKCPIKTNARSCTIIPSFVGAKFLVHNG--RHYLPVNVTEEMVGHKLGEFSFSYRLTKNK Conpu1 FP-NLRDAEIKTDARACTILPNFVGIRFLVHNG--KQHQPVTVTQDMVGHKLGEFAFKYKQTKNR Copci FP-NLKEATINTTARSCTILPNFVGVRFGVHNG--KEYVPVLVTQDMVGHKLGEFAFTFRCVVRR Croqu1 FP-NLAEAAIRTSARACTILPNFVGLKLLVHNG--KDYVPVNVTAQMVGHKLGEFAFSYKASKNR CryneH991 FP-SLSHHPIFTKSRASTILPNFVGIKFMVYNG--KDYLPVTVSEEMVGHKLGEFAWTYRKTKN- Crypa2 LP--LVRPPIRTQARGATVLPSFVGLTFEVYNG--KVYNPVTITEDMVGHKLGEFSFIYDK---- Debha1 VPLPIANAPIRTNARSCTVLPQFVGLKFQIHNG--KEYAEVEITDDMVGSKLGEFAFTYKFSKN- Dekbr2 VPLPISQAPIRTNARACTILPQFVGLKFQVHNG--KDYVQFEVTENMVGSKLGEFAFSYTQTKNK Dicdi ---ELQNYTIVTTERSSVIVPYYLTKTIYVYNG--RKYVGVKITEKSLGRKLGEYVYKASGKSKK Dmel ----------------------------------------------------------------- Enthi ----------------------------------------------------------------- Falba ----------------------------------------------------------------- Fomme1 FP-NLRDAPIQTDARACTILPNFVGIRFMVHNG--KTYVPVNVTQDMVGHKLGEFAFVYRQTKNK Fusgr1 YSLPIVWPPVRTQARSATILPNFVGLKFEVHNG--KDYHEVTITEDMVGHKLGEFA--------- Galma1 FP-NLRDAPIKTQARSCTILPNFVGVRFMVHNG--RDYLPVLVTQDMVGHKLGEFSFTFRCVVRH Ganpr1 LPAALIRAPVKTAARSGTVLPSYVGKTFAIHNG--KQFVPVTVGEGMVGRKLGEFVFKGGKTK-- Gloin1 FP-GLRQAPIKTQARSCTILPAFVGLKFLVHNG--KDYIPVTITEEMV----------------- Hisca1 MP------AIKTQARSATILPNFVGLKFAVHNG--KTYNEVFITDEMVGRKLGEFSFSIRHGDGE Klula1 VPLPIKEAPIRTNARSATILPQFVGLKFQVHNG--KEYVAFEVTEDMVGSKLGEFVFSYTQTKNK Lacbi2 FP-NLREAPIKTQARSCTILPNFVGIRFMVHNG--KDYIPVNVTQDMVGHKLGEFSFTYRATKRS Lenti61 FP-NLKHAAIKTQARACTILPNFIGIRFLVHNG--KDYIPVTVTQDMVGHKLGEFAFTYKQTKNK Malgl1 FP-NLQQAPIRTNARSCTILPNFVGLKFLVHNG--KFHLPVTITEEMVGHKLGEFAFSYR----- Mellp23 FP-NLAEAAIRTSARSCTILPNFVGLKLLVHNG--KDYVPVNITAEMVGHKLGEFSFSYKASKNR Mnele ----------------------------------------------------------------- Monbr --------MSNKNTRNITITPEDVNKNINIETGNSKKSVKINVTIKHIGHKTGEFAAVYKRKSKR Morel2 LP-GLRQAPVRTNARACTIIPSFVGLKFQIHNG--KDYTPLTVTDEMVGHKLGEFAFSYRQTKNR Mucci2 FP-GLKQAPIATQARSCTILPSFVGLKFLVHNG--KDYLPVHVTEEMIGHKLGEFAFTYRFTKAK Mydma ----------------------------------------------------------------- Neucr2 VPLPIQRPPIRTQARSATILPNFVGLKFQVHNG--KDYIDLTVTEEMVGHKLGEFSFIWGKKK-- Orpsp11 ----------------------------------------------------------------- Pench1 --------PIRTTKRAATILPNFVGLRFAVHNG--KTYVEIQVTEEMVGRKLGEYVFTYKQSKN- Phybl2 FP-GLRQAPIATQARSCTILPSFVGLKFLVHNG--KDYLPVHVTEEMIGHKLGEFSFSYRFTKAK Picst3 VPLPIAEAPIRTNARSCTILPQFVGLKFQIHNG--KEYVEVEVTDNMVGSKLGEFAFMYKYTKN- Plicr1 FP-NLRQAAITTQARDCTILPNYVGLRFNVHDG--KSYVPVTVSQDMVGHKLGEFAFTYKMSKNK Polpo ----------------------------------------------------------------- Pucgr2 ----------------------------------------------------------------- Punst1 FP-NLREATIKTQARSCTILPNFVGIRFQVHNG--KQYLPVTVTQDMVGHKLGEFAFSYKQTRNK Rhior3 FP-GLKQAPIATQARSCTILPSFVGLKFLVHNG--KEYIPVHVTEEMIGHKLGEFSFTYRFTKNK Rhoto1 FP-GLAEAPIRTTARNCTIMPFHVGATFLVHNG--KDYIPLHVTPAHVGHKLGEFAARHTPSKGR Rozal11 ----------------------------------------------------------------- Sacce1 VPLPIREAPIRTNARAATILPQFVGLKFQIHNG--KEYVPIEISEDMVGHKLGEFAFSYTQTKNK Salro ----------------------------------------------------------------- Schco3 FP-NLRQAPIKTQARSCTILPNFIGIRFMVHNG--RDYVPVMVTQDMVGHKLGEFAFNWKGNKGR Schpo1 FGVNVQQCPIKTAVRSATILPRMVGAQFMVHNG--KSYANVKITEDMIGHKLGEFAFHYRQTKNR Sorma PPLPIQRPPIRTQARSATILPNFVGLKFQVHNG--KDYVDLTVTEEMVGHKLGEFSFIWGKKK-- Sphar ----------------------------------------------------------------- Spipu1 FP------PVKTMARASTILPSHVGRKFLVHNG--KDYIPVLVTEQMVNRKLGEFAFSFKKKDDK Sporo1 FP-GIAEAPIRTSARACTILPNFIGLRFLVHNG--KQYVPVHITPEMVGHKLGEFAYRGR----- Stehi1 FP-NLREAPIKTQARDCTILPNFIGMRFQVHNG--KEYIPVTVTQDMVGHKLGEFSFTYKMSKNK Tapde11 FPTSLAEAPIRTQARSCTIIPSFVGLRFMVHNG--KNYLPVEVTDEMVGHKLGEFSFSYKQTKNK Thetr ----------------------------------------------------------------- Treme1 FP-SLTNAPIYTKSRACTILPNFVGIKFMVHNG--QHYLPVQVTEEMVGHKLGEFSFSYRQTKNR Trire2 VPLNIVFPPVRTQARSATILPNFVGLNFEIHNG--KDYHQVTITEDMVGHKLGEFA--------- Umbra1 FP-GLRQAPIATQARSCTILPSFVGLKFLVHNG--KDYIPINVTEEMIGHKLGEFAFSYRFTKAK Ustma22 FP-NLADAAIRTNARSCTILPNFVGLKFLVHNG--KHHIPLTVTEEMVGHKLGEFAFRYRLTKNK Walse1 FP-NLLELVIKTNARNCTILPNFVGMKFAVHNG--KNYIPIQVTESMIDYKFGFFVFSYR----- Zygro1 VPLPIKEAPIRTNARSATVLPQFVGLKFQVHNG--KEYVAFEVVEDMVGRKLGEFAFSYTQTKNK [Cluster2950.fasta_al_trimmed; alignment length = 173] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 TIAWNPTGQLIATGSADRTLRIWIEKVLFNPVELASCSDGTVRFWDMSWSADGRILMATNATTFPDLHLFAT-TGEGTVKIMSYTLHAHTSACLSIALAPTGRYLAVGGSDALISLWDT-TDWICRRTVSAVRGVSWSFDGRFVCGACGGNGLEIAETGESVYTVTVAWHPSR Aurde31 AVAWSCDGKYLASCGYERSVRVWVECISWDPTILCSASDMKVAFWDIQFCPTGKRVLVAMSAVWTGSA-IFTGGTDGSIRVIEYKITAHVGHCYALALDPRGKYLATGGADSIVSLIDL-EQWLPVRAFSTVNALSFSHDGEYLAIAGDHPYVELSETGQVMHRVSVAWHPSK Batde5 SVKWNCDGRRVASGSADKTARIWVSKAVWDPDKLATASDCSVRLWDMCWSPDSRCIAVINELDWAGDLLFLT-TGEGTVKIIEFSFKAHTANAYCIEFDPRGRYFATGGADAIVALWDI-ETLTSLQTFSPIRALSFSFDGDFIVYGSDDKCIDIVESGEHIFTLSLAWHPTK Botbo1 NVAWSCDARRLATCGLERHVRLWVNAVAWNPTLLCASGDKKMCFFDLEYSPDGQMLLATHHAVFSGD-IVFSAGGDGMVTMFDVKTGCHVRSCYTLDFDPRGKYLATGGADAIVNLYDV-SEWICIRTITTVLSVAFSYDGEYLA-SGCDNYIDLTETGQHIHRVSLAWHPTQ Botci1 TISWNPLGSLIATGAADKTLRVWIEKVAFNPVELASVSDGVVKFWDLVWHPNGESLIVTNQIAFSGDKIFLT-TGEGRIKILSYTLNGHTSSCLSVEMQPTARFLASGGSDSIIALWDT-TDWICQRTLIPIRSISFSFDGSYIVGGSEGSGLEITETGEHVYTVVVAWHPNK Caeel SIAFNCDGTKLVCGAFDKKVSVAVEQVACSEKLFASASDRNICVWDISWSPCDEYFIFSHELTFLSNHVFVA-ESGGKVEILKFQAHSHQVECLAVSISKDGRKLAVGASDASCSLWDL-EELICERVIPGIRAVSFSCNGQLLASGSEDHSIDIVPDGSRCHEISVAWHPNS Canalb1 TVAINQTGTRVVYSRTDRSVRIWVECLSFNPMTFATVADEYVKIWNVRYSNDGQLLVVIYDLKWHDHQFFLVSSHDGSILLYEISVSGHNSSITTIAISPKGNYFTVGSSEGVISFWKTLENLINSKVITSIAQLDISRDGTYLAVAYTDSNSRIAEGSELVHEISIVWFPTK Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow AVGWNTEGRYLGTASLDKSLRIWIDKLCWSPTTISTCSDRTVRIWDLAWSPDGQTIAVANEMAWEGDIFYIS-TGLGAVQMYQFTVQAHTGNCVCIRFDPKGRFFATGSADSLVSIWDA-YELICLRTVQPIRAIGFSHDSQFIASASEDKFIDIVDNAESVYQITLAWHPKE Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------SLNGHTANCICIEFDSTGKYFATGSADALVNLWDT-NELICVRTFSPVRTLSFSSNGQLLASASEDLFIDIVATGEKVCEVTLAWHPKH CocheC53 SISWNASGTFIATGAADKTLRIWLERVSFHPIELASCGDGMVRFWDLAWTPDGNEIVVTNQCAFSGNHLYST-AGDGSVRLLRYTLNAHTSACYAVSMSPSGEYLAAGGGDALVSLWDT-QEWICVRTL-LVKSVDFSFDGSYITAGSEEKKIRIVESGETVHTIHVAWHPCR Coere1 SLSWSSDGNLLTASGSREPVRSWIERLAWCPAILAAASDKVVHLWDISWSSSGKYLAVINSIRWDDQLIFIA-THSGTVEVISWMIPAHAVSCNCIGIDPRGKLLATGSADATMELWNM-EDFSLFCTINPLHFTDFSMDGRFVASASDDLEILITFSGKLVHRLALAWHPRN Conco1 SCSYSPVGNKLAIGESGSKIRIWIEGLCWHPDTLASISDKRLVVWNIHWSKDGKLILVINQFTLDLKKLIIA-SNNGYVHFFNLSLRISSSTCHSLDLHPSGNYLCVGTADATASLIDL-QTFKIIVNYSTIRSIKFNHDGQYVAMCSRQSMIYITFTGKLQGFFNLNWHCKK Conpu1 HVAWSCDGKRLAGVGIDKIVRVWVDYVTWNPTLFCTSSDRRIVFWDLNYSPDGRSLLYATTAMFAGDGVVLTHHSEHSLRILDYNPAAHVGGCVAVALDPRGRYLASGGNDSIVDLFDV-NEWICARTITGVNALSFSYDGEYIAIASGGQYIDITETGVPLHRVTVTWHPSK Copci HLAWNCDGKKLAVVGIDKAVRIWIDHISWNPTLFCTSSDRRIVFWDTCYSPNGRHLLCGVTGIFTGDGVVTSYPYLNTIFLFDYQLPAHVGGCAAFALDPRGTYLATGGTDSIVNLFDT-NDWLCTRTITAINKLSFSHDGEYLAIASDGPYIDIVETCQPLHRISVAWHPSR Croqu1 TLGWSVDGKKLASGSKDEGIRIWINQLRWDPTRLASAGDGTLRFWDLCWSPDASIVAIINEVSFSGDYFFIP-TGVGEVVTYKFRSSPHACTIYCIDTDPRGRYIAVGGADSTVSLLDL-EEFYCVKTFADVRTISFSYDGDFIAVAGKDLFIDIVSSGTQVRKISLAWHPSK CryneH991 TVAWSSDGKKAATGGEYKEIQVWVSSIAWSPVVLVSAD--------LAWHPSGQHFAAINSLRFSGRLVCAV-SNDGSVSAWIYHVVCYAASLLSLAYDPRGRYFVVGGQDALLSLFDT-KEWICERSFDAIRHTAFSYDGEFVAIGGDDLFIAIVYTGQTVAKIALSWNPRK Crypa2 SIGWNPFGNLIATGAADKTLRVWIEKVAFNPVELCSVSDGTVKFWDLVWDPEGESLIVTNQIAFSRERVYVG-TGKGEVRVLSFALKGHTGSCLSVELSPSGKYLASGGTDSLVSLYDT-RDWMCHRTLTPVKTLSFTWDGFYLVAGSQSTGIDCCESGERVHTFVVSWAPTR Debha1 HISINLTGTRLVNSRTDRSIRIWVERVAWNPKSFATVGDDLVKIWRVAYSNDGEILTVIYDILWHGHSFFMCALHDGSVPIYKIKLLGHRSSATCVVVDPRGKYFAVGSNEGVVSLWNT-SSMLISKVLTAIANIDISRDGTYVAVAYSGENIKIYDTTEQVYEVHVAWFPSK Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi SVAWNANGTKIASSGSDGIVRVWIEKISWSPKLLASAGDKVIKIWDVRWSPDGQFIVALNQVGWNGDLILMA-NSMGNIEAYKFTLYGHTASIYCMEFDPTGKYLAAGSADSIVSLWDI-EDMMCVKTFIPCRSVSFSFDGQFIAASSFESTIEIIESSQPIHTISLMWHPTL Dmel SVCWNADGRYLASGSFDKTVVVYVDQLCWHRTQFATASDKTVRIWDIAWSPDGKTIAVVNEISWTNDLFFLT-NGLGCMHILSYTLKAHPANCICIEFGPTGKYFATGSADAQVSLWDA-NELACLRMISPVRTISFSHDERMIALASEDLIIDITETGERVTDITVAWHPKQ Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 HVAWSCDGRRLASVGIDKAVRIWVDYVTWNPTLFCTSSDRKIVFWDINYAPDGKTICFASTALFAGNGLVLSHFRQNTVMIVDYQPAAHVGGCLAVALDPRGRYLASGGNDSIIDIFDM-TEWICVNTITSITSLSFSHDGEYLAVASQGSYIDVVETGLPLHRIAVTWHPSK Fusgr1 CIAWNPLGTLVATGSSEKTLRVWIEKVAFNPTELCSVSDGVVKFWDLVWAPDGNSLLVTNQIAFSGEKIFVT-TAEGRIRVLSYELNGHTSSCLTADLQPTGRYLATGGSDSVIALWDT-TDWVCQRTITPVKSLSFTFDGSFVVGGSEGSGLEIVETGEHVHTFVVAWAPTR Galma1 HVAWSCDGKKLAAVGIDRLARVWVDYVAWNPTLFCTSSDKRIVFWDMSYAPDGQSMLYGSTAIFVGDGVVVSMQTEHTLRVIDVSPAAHVGGCIALALDPRGVYLASGGHDSIINLFDL-NTWIVARTITGITALSFSHDGEYLAVANTGTYIDITETGAPLHRVTVSWHPSK Ganpr1 GLEWNIEGTRLATCGADKFIKIIVNTVCWDPSRLVSGSDRTVKIWDLAFSPDGKHVAVVNELLYTGDYLLVA-TLDGDIMVLGATVRGHMANIYSIKIDPKGRYLASGAADGIVSIFDA-YELICLRTYTPVRTISFSHDGDFLAAGSEETSIEITETCLPVAKVVVAWHPHR Gloin1 TVAWNCDGRKLASGSVDKTVRLWVDQLCWSPQELATASDKTVRFWDISWSWDGSMVAVINEISWDCSLFFLT-TGSGAIKILKWVLRGHTANCYCIDFDPKKRYVAAGGADALVTLWDL-EECVCLRSFKPVRTISFTHDGVYLAAASEDEHIIVVETGKTVYRISVAWHPKG Hisca1 TLAWNPTGSLIATGSVDRTLRIWIEKVTFNPVELASCSDGTVRFWDMAWTADGSVILVTNATAFSDLDLFLT-TGDGTVKVVSYTIHAHTSACLSIALSPTSRYLAVGGSDALISLWDT-TDWICKRTVSAVRGVSWSWDGRFIVGACGGSGLEIAETGESVYTIAVAWHPSR Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 HVAWNCDGKKLAAVGIDKITRVWVDYVSWNPTLFCTSSDRRIVFWDTSYSPDGRSLLFGSTAIFVGDGVILTHHSEHTLRVMDYSPAAHVGGCVALALDPRGRYLASGGYDSIVNMFDL-NDWICARTITSISALSFSHDGEYLAIANAGPYIDITETGVPLHRVTVTWHPSK Lenti61 HVAWSCDGRKLGAVGIDKVARVWVDYIAWNPTLFCTSSDRRVVFWDLNYSPDGKTILYASTVTFVGDAIFLTFSTESNLRIMSYSVPAHVAGCQTAALDPRGRYLASGGNDSIVNLFDL-SEWLCARTITAVTGLSFSHDGEFIAIASAGSFIDIVETGMPLHRVTVSWHPSK Malgl1 ALAWNATGDVLMSCGSDHVVRAWISAIACHPTLFATGGDRTVRVWDLAYHPQGRFLAVINELAWDGSMLLLP-MGSGTISFLRAIHHAHPAAIFCVKWDPTERVVATAAADSTLALWDS-ALWDCSRVFSPLRTIDFSFDGEWLAVGGEDPDVALLAGERIVHRISLAWHPSK Mellp23 TLGWSVDGKKLASGSKDEGIRIWFSELRWDPTRLASAGDGTLRFWDLCWSPDASVVAI-NELAFSGEYLFLP-TGAGEVVTYGFRCTPHAAVLNCIDTDPRGRYIAVGGADSIVSLIDV-EEFYCVNTFADVRTISFSYDGDFIAFAGKDTFIDIVASGAQVRRITIAWHPSK Mnele CVAWNCTGKYIASGSLDKTAIVQVDQIAWHPSMLSTVSDKTLRLWDMTWKSDGSTIALVNEIGWTDQHFYLT-SGNGSIHITEYQIPAHTAHCICLKFSPDKEHFATGGADALINIWDA-SELSYLTSYSPVRTLSFNHDGRLLAAGSEDLVIDIVETGEKVATVCVAWHPSQ Monbr GLRFNADGTLLASSGIDKLVIVHVDQVAFHPQILASASDKSVKLWDLKWHPDCNLLAVVNGLSWDATGFFLT-TGRGSVRVLHPDLTAHTSNCLSIEFSPCGRYFATGSADATVSLFDA-HELICFRTHNVARSIGFSYDGDVFAACSPQDHLDLTESDAVLHSIAVTWHPTK Morel2 TVGWNCDGRRLASGSVDKTARVWVDQLRWDPTHLATASDKTVRIWDISWSPDGQCIAVVNEISWAGDLFLLT-TGQGTVKIMAYVLDGHTANCYCLELDPRGRYLATGSADALVNLWEM-NDFSCVRTFGPIRTISFSFDGEFIASASEDLAIDIVESGETVHKITVAWHPSK Mucci2 SVAWNADGRRLASGSVDKTARVWVDQLDWNPTRLATASDQTVRIWDICWSPDGNDIAVVNEFTWANNLFCVT-TGQGNIELYDYTGRGHTSSCYSVEADPSGNYLAAGSADGSVSLWDM-ESMNCVRAFGPVRTLSFSFDAQYIAYASEDHFIDIVQSGESVKNITVAWSPRD Mydma SVGWNCNGRYLASCSFDKTVSIYVDQLCWHPSLLVTASDKTVRVWDICWSPNGKTIAVVNEISWTNDLFFLT-NGHGHINILSYTLNAHPANCICIKFDPKGRYFATGSADALVSLWDL-DELCCVHCFSPVRTLSFSYDGKMLASASEDLFIDIVETGEQICEVTVAWHPSE Neucr2 TIAWNPLGTLIATGAVDKTLRVWIEKVAFNPVELCSVSDGAVKIWDLAWAPDGSSLLVTNQMAFSGDKVFLP-TNEGRIRILSYTLKGHTASCLTAELSPTGKYLATGGADSIISLFDT-KDWICQRTVTPVKSISFTFDGSYVVGGCEGGSLEVTETGEHVHTFAVAWAPTR Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 TLAWNPTGQLIATGSADRTLRIWIEKALFNPVELASCSDGTVRFWD------------TNATTFPEQHIFVT-TGEGKVKIMSYTLNAHTSACLSIALAPTGRYLAVGGSDALISLWDT-TDWICRRTLSAIRGVSWSFDGRFIVGACGGNGLEIAESGDSIYTIAVAWHPSR Phybl2 TVAWNCDGRRLASGSVDKTARVWVDQLDWDPTRLATASDKTARVWDICWSPDGNNIAVVNEIAWANNLFYVT-TGQGTIKVYEYSLRGHTANCYCVEADPTNRYLAVGSADAMVTLWDM-EKYTCVRAFSPVRTLSFSYDGQFIASASEDNFIDIVESGESVHHITVAWHPRD Picst3 LISINNTGTRLVTSRTDKSIRIWIELVAWNPKSFVTVGDTYVKLWKVSYSPDGELLAVVYEIQWEGHLYFICALHDGTLPIYKVQLTGHRSSATAVKIDPRGTYLAVGSSEGVISLWNT-ATMLNSKVITSISSLGISRDGAYVASSYNGSNIIINEAGKKVYEVCITWFPNK Plicr1 HVAWNCDGNKLAAVGIDKLTRIWVDYVSWNPTLFCTSSDRRIVFWDTSYSPDGRSLLYASTAMFAGDAVIMTHHSEHTLRVMDYSPAAHVGGCIAVALDPRGRYLASGGFDSIVNMFDL-SEWICARTITAINALSFSHDGEYIAIASAGTYIDITETGVPLHRVTVAWHPSK Polpo SVAWSCDGKKLASGGMDHLVKVWIEQLKWSPVVLATASDKTVRIWDLGWSPDGTLIAIINEISWKGELFFLT-TGTGILEVMAWSINAHTSNLYTIEIDPLGRYFAIGAADSVITLWDI-EEMFCVRSFTPVRATSFSSDGQFLAYSSEDPIIEIVETGQAVYQVSIAWHPTL Pucgr2 TLGWSVDGRKLASGSKDEGIRIWINQLRWDPTRLASAGDGTLRFWDLCWSPDASIVAIINEVSFSGDYLFVP-TGAGSVVTYAFRYEAHACVINCIDIDPRGRYIAVGGADSIVSLIDL-EEFYCVNTFADVRTISFSYDGDFIAVAGKDFFIDVVSTGQQVRKISIAWHPSK Punst1 HVAWSCDGRRLAAVGIDKSARVFVDYVSWNPTLFCTSSDRQVVFWDTDYSPDGRTLLYASTATWTGDAIVLTHHQETTLRVLEYKPAAHVAGCMAVALDPRGGHLASGGRDSIVNIFDL-SEWISARTITSITALSYSHDGEYLAIASAGSYIDITETGAPLHRVTVSWHPSK Rhior3 TVAWNCDGRKLASGS--------VDQLDWDPTRLATASDKTVRLWDICWSPDGNHIAVVNEIAWANNQFFVT-TGQGTIKVYDYNLRGHTANCYCVEADPTSKYLAVGSADALVTLWDT-RTFECVRSFEPVRTLGFSFDGQYIASASEDHFIDVVESGESIHHITVAWSPRD Rhoto1 TVAWNLDGRRLAAGGSP-SLRIFVSCVRWSPVRLASVSDKALHFWDMNWSPDGKTIVVTNDTQFNGSLLY-T-GVEGSVRISAFTVPMTSMPVGMLDLDPRGRYLLAGGNDATVSLWET-EEWTCAASAGPLLTCRFNHDGSLVASIA----VVIVPGLKKEHSIDLAWHPSR Rozal11 SVSWSCDGKKLASGSTDSTARVWVEQVAFHPSLLATTSDKTVRIWDLCWHPNGQMIAVVNEVTWKGDKFFIT-TGLGTVQILSYTINAHTSNCYCLKFDPKHRYLAVGSADALASLWEL-DTLTCLKTFTPIRCLSFSHDGEFLAMASEDSHILITETGKQVFKVSIAWHPNK Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro CLDWDCEGGMLGSGSMDKTACVMVDFLTWHPNVLATASDHHVKFWDVRYAPDGNTLAVVNEFTWSGKHLFLT-NRQGRVEVYTFAITAHTASCTCINFDPTHR--------------------------------------------------DI----------SVA----- Schco3 HVAWSCDGKRIAAVGLDKMARVWVNYVSWNPTMFCTSSDRRIVFWDTNYSPDGKHLLYGSRGIFAGDAVIVAHTGIHSLDVYNFTVSAHVGGSTSIAMDPRGRYLASGGLDAIVNLFDL-DEWICARTVTSINAVSFSFDGEYLAMATAGSYIDITETAAPLHRVTVAWHPSQ Schpo1 SLGWNLSGSRLASSSSSGSVLVWVEQLVWDPTRLMAVYGKMIRFWDATWSPSGNYCCATNECCWSEDLFFMT-TGLGTVQIMEWDIKAHNSNCFCIEFSPDNRHLAIGGADAITSLWDP-QELICERSITPIRTLSFSYDSRYLASGSEDRYVDITKTGDQIWKIKVAWHPTK Sorma TIAWNPLGTLIATGAIDKTLRVWIEKVAFNPVELCSVSDGAVKIWDLAWAPDGSSLLVTNQMAFSGDKVFLP-TSEGRIRILSYTLKGHTASCLTAELSPTGKYLATGGADSIIALFDT-KDWICQRTVTPVKSISFTFDGSYVVGGCEGGSLEVTETGEHVHTFAVAWAPTR Sphar HVAWSYDGTQLASASSDNTIKIWVEHMSFNPKQLFTCSDKSVRLWDSAWSPDGKYIAFVNQLSWTGEFIVLA-MGSGMIQPIPWPIKAHGGGCVSVAFDPKGRYLAVGSVDTQTSLWDL-SEMASLRTFNPVVSLSFTFCGTYLASAAELDQIDIVESGESVHQIAVAWHPSK Spipu1 TVGWNNDGRKLASGSADQTARVYVDQLCWDPTRLATASDSSIMIWDICWSPDGRHIAVINEISWAGDLFFMT-TGQGTVKVLEFDLTAHTANIYCVEFDPRGKYFATGSADALICLWDI-EEFICVRTFGPIRTISFSYDGELIASGSEDRIIDIVETGESVHTISVAWHPTK Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 HVAWSCDGKKLAAAGMDKAVRIWTDYVSWNPTLFCSSSERRIVFWDTNYSPDGKHLVWATTAMFVGDGLILTHISEYQVRIHDFSLPAHVGGCIAAALDPRGKYMASGGYDTIVNIFDM-DELICARTITSVTALSFSHCGEYIAISNIGKYIDIVETGAHMHRITVAWHPSR Tapde11 SVAWNSTGSRVASASTDRTVRVWIEQVSWDPTRIASASDRSIKVWEVQYSPDGKFLAVIHQIVWSGHLLCLS-TQQGTVKVFETEIEGNTSSVFCLEFDPLGRYLAVGGADAIISLWDL-RDWICVRTFNPIRTLSFSFDGAYIASGSEDNFIDIVETGEQVHTIAIAWHPNK Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 SIAWSCDGKRVAVGTEYKGLKVYVAALAWSPVVLLSGCGSSVVLWDVTFHPSGDHFAVINSLRFSGKLLLAV-SNDGSIASWVYHSVVHCSSLLSLSLDPTGKFLAVGGQDALLSLFDT-KDWICVRTFDAIRHSAFSPDGEMIAVGGDDSYIVVIYTGATIAKFSLAWHPKR Trire2 SIAWNPPGTLVATGSADRTLRVWIEKVAFNPTELCSLSDGVVRFWDLVWAPDGQTLLVTNQIAFSGKKIFVT-TSEGQIRILSYTLKGHTAACLTAELQPTGRYLATGGANSIIALWDT-TDWLCHRTVTPVRSISFTFDGSYVVGGSEGNGLEVVETGEHVHTFVVAWAPTR Umbra1 TVAWNCDGRRLASGSVDKTARIWVDQLDWDPTRLATASDRTVRLWDICWSPDGNHIAVVNEISWSGDLFYLT-TGQGTIKIFDYTLRAHTANCYCIEIDPRGRYLAAGSADATVSLWDL-ESYTCLRSFTPVRTISFSYDGQFLASASEDSYVDIVRLGQSVKHITVAWHPFE Ustma22 GLGWSVDGRKLATCGADRTVRIWVDQLVWNPVVLATASDKTVRIWDISYHPSGKYLAVINELAFDGSLLLLS-SGSGSIHIHHTSHPAHTANVFCLQPDPLSRYIATASSDSMISLWHS-TEYVSLKMLTPARAIGFSFDGELLAAGGEDAFITIIVGNDELATITLAWHPSK Walse1 AVGWSNDGKRLGSVSSDKSLRIWVVQLAWHPLLLTTVSDKTIRCWDLAYHPDGQTLAANHDFRWDGELFTIC-CNDGSFEAYLYSDKGHTSDATKIEFTKDRRYMLTGGGDAVVNVWDL-EEWICLRSINLVRSISVNSISECVAIGTDDRNISIIHTGETLHSFSLAWHPSK Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster2953.fasta_al_trimmed; alignment length = 266] Allma1 LA-AGAPTPREAASYLRRVHLAWPPPGTASVAADLAAMARLAVHPVVVVHDAASQLARLIDGHTPVIAPLAPAGDATVALARKLVVLNKSDGGVPAVNLANEAVRDLDLVEAALSGMPPTATAVVAGWAAVAHVLTDKP-------TVVRAGPKVLDRAKVVDLLESAFGRSLDGDAYFARLDTHLAVIAG-DYAGAAIVTRECMYLDKLAVHPRQTAGG-GLVDVVWRGLR-EELVWRSRGNNPVNAWYFDRADGWTVFWVPASF Ashgo11 LK-S-TATRREAKDYLTKLYLRGTSAGLIDFAIMLGRLRLLGIRPLVVLSTESEILRETFYSIIPIIMPFVDEVAFMRELVAKFFIINR-YGGIVFVNLSQEYLTDLELMSAVLSLLLPSSTGLITYNPLLYNVLTDRSLSSSL-PTVLKQGVDIVNLTKLKGIIEHSFDRNLDMSHYLKRINGKIIIVIG-DYEGIAILTYEFAYLDKFAVLPH-LRGSLCISDVIFNLMFKKELVWRSRRENVVNNWYFQRSVGFKLFYIEPSW Aspfu1 LS-S-ATTKREAKSYLARVRLSTPDDNIIGVAKTLSQLNRLGLTCCVVVDEQADRLAVAIQGHTVILTPIAPANDAVIALTKRVILLDP-LGGIVFINMEQEYLENLRVAQKALAMLPAASSGIITRNPLIHNLLTDKPLSSSL-PTFVKRGMPLIDLPRLVHLIEDSFDRKLDVQDYLNRVNDRLLIIAG-EYEGGAILTWEVPYLDKFAVLKR-SQGAGGVADIVFNAMVRSGVCWRSRKNNPVNKWYFERSLGWTMFWIQPSW Aurde31 LR-A-GPSLRDTKGYLASVKIQGPSDRQLSIARGMVYLEKLGLVSIIVVEEDAMRVAAALEGEIPVLPPLVDANDMLAALARRLMIINR-EGGILLVNLSSEYLSNLALARQCLSYMPPSASAVMVPKALIGNLITNKPASSSL-PTVIRRGLPVVDRPKLAALLETSFRRTLDQDAFFLRLEQTLVIVAG-DYAGAAVVTNEIAYLDKFAVAPA-HQGD-GTVDFLWVALHDEDLVWRSRADNPVNKWYFERASGWVLFWIPSSW Batde5 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 ----------------------------------MVYLEKLGLVSVIVVEEETMRVVKALEGEIPVLPPLADSDDVLAALARRLMIINR-EGGVLMINLSSEVLSNLRLAQTCLNYMPRSSSAVIVPRSLIANLITNKPASSSL-PTLIRHGLPFIDQDRMTALLEQSFGQKLEADAFYDRLNRSLAIVAG-DYTGAAIVTKEITYLDKFAVLPS-HQGD-GTVDFLWGALQDEDLVWRSRANNPVNKWYYERSSGWVLFWIKSSW Botci1 LG-S-SATKREARSYIQNVKVRAPDDETLGIGKTLSKLCRLGLISTVVVDEQAARVVTAIDGVLPVLPSIGTASDVVLALTRRLILIDP-LGGIVFLNMEQEYLDNLELVRSALAILPPSSSALVTRNPLIHNLLTDKPASSSL-PTFAKHGMPVIDLPRLVHLIEDSFNKKLDVQDYLRRVNNRIVIIAG-EYEGGALLTWEVPYLDKFAVLKR-SQGSGGVADVVFKSMVRDGVCWRSRKDNPVNKWYFERSRAWTMFFIEPSW Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 LK-S-TTTKREAKNYLTKLFINRFSNPFIGIAETFKRLITLGISPIIMLDKMLNYLGHPEEGIIPIIQPIVASDKLLLGLSSKIVMIDP-IGGIVFINLSQEYVDNLNTMNNVLSYINEKSTGIITLNPIIYNVLTDRAISSSL-PTIIKKGVEVVNKEKLIDLLNDSFGKSLDVGPYLDRINKNIVVIVG-DYDGAAIITWEIAYLDKFAIAKK-NQGLPGLADVIFKIILQSELIWRSRKNNPVNKWYFERCCGWKIFYITPSF Cangl LN-S-TATKREAKDYLIKLLIRNISERSLRLSDSIRRLKFLGISPVCVLLTEVEKMDKLITGIVPIVKPYIDPVLFMDQLSRKFFILNR-SGGIIFINLSQEYMENLQLMNTVLSNLSSSATGVITVNPLVHNLLTDRSISSSL-PTVLKKGVDILDLVKFKNIIDKSFGRELDLNHYLNRINGKIIIIIG-DYEGIAILTYEFVYLDKFAVLPH-LKGSLGISDIIFNLMFKKEVVWRSRANNVVNKWYFQRSVAFKLFYIKPSW Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 LA-AGAPSPREAASYVRKVQLQWPSPSAANVAANLVALHRLAVTPIIVVDTACDQVARALHAVIPVLAPLATLALAMTALAKKLVIVNRARGGIAFINLAMEFQDDLAQAQRVLSVLPPSATAVIASAAIVSHYLTDKPLAVSL-PTVLRLGVPIVNILKLTHLLESSFGRQLDADRFYTRIASRLVVIAG-DYSGAAIITLEVPYLDKFAVSPK-VQSG-GVADILWMTLRDDGLVWRSRADNKVNPWYFARSDGWAVFWVPASF Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LK-E-SPGKRDARNFLKQVKLRQPDDRVLDIALTLSQMAQLGFSVAVVLDEQALRMVAALEGVIPVITPFAQADDVLLALIRRIIILDP-LGGIVFVNLEAEYLKNLEVVQRGLKLLPPSSSGLILKNPLLHNVLTDKPMSSSL-PTFFKKGIPLINFPKLVDLIDDSFRRKLHPQNYLDRIRGRVIIIAG-DYEGGAICTWEIPYLDKFAVLTS-SQGSGGVSDIVWAALTRTGVVWRSRTSNPVNKWYQERSKGWTMFWIEPSW Coere1 LS-T-VPSPREARKFLNSVFIDGLSDGECRTGKLLAQIQRIGVTPVVLLGKRVHQLSDAIEGQTPIISPLMRTQAAAPALARRLILLGS-SDGLRFINLEEDYAETLDLMRMCLGILPPTAAGIVAPSLVLKGLISERPVTPSYKPTLLRHGFRICDLSRLQALLESSFKRTLDGASYFDRLRTLEIIIAG-DYQGAVVATHELPYLDKFAVLPA-AQGT-GMADILWAQLRRASCMWRSRNDNGVNKWYFDRSNGWVFFWIPPSF Conco1 LK-S-MPSKREAKSYIKKVNLIVPYKEELQVAQTLAYMQRLGLYPVVVLENDGLALSELLEGAIPIVLPICSSFDAMCALSKKVIVINN-RGGIPFVNLQQDF-SDLNIVMQCLEYLPATTSAVVLINAVIGNLITDKPLSPSL-PTVLRYGLKTVDQYKLWKLLNDSFGKEVDIPKFKARLDKVLVVIAG-DYQGASIVTLETIYLDKFAVGPQ-HQGI-GVADLLWKQLLADDLMWRSRDINPINKWYFERCDGWVMFWIPPSF Conpu1 ----------------------------------MVYLEKLGLVSVIVVEEETMRVVSALEGEIPVLPPFADANDVLGALARRLMIINK-EGGVLLVNLSAEHLANLNLARTCLAYMPSTSSAVMVPSSLIANLITNKPASSSL-PTLIRRGLPIIDRVKLKYLLETSFRRELNEDAFYARLERDLVIIAG-DYVGAAIVTNEISYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRADNPINKWYFERSTGWVLFWIPSAW Copci LK-A-NPSLRDTRSYLASVKIQGPTDVQLSITRGLVYLEKLGMVSVIVVEDEIMRVVTSLEGEIPVLAPFADANDAIAGLACRLMIINQ-RGGVLLINLQQEYLSDLALARTCLRYMPPTSSAIMVPSSLIGNLITNKPASSSL-PTLLRRGLPIIDKEKMTALLEQSFGRVLDQEAFYGRLEKTLVIIAG-DYDGTAIVTNEISYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRSNNPVNKWYFERSTGWVLFWIPSSW Croqu1 LQ-A-HPSVRDSRLYLKSVKIQGPTDRQLSIIDGIIYLKTLGLVPIIVVDHETTRLANMIESEIPVLSPVATADEALKALAARLMIINR-EGGILSINLASEYLANLKLARACLAKLPNEASALIVPKSLIANLITNKPASPSL-RTLIRKGLPIVDQDKMTQLLEASFRRRLGAQAFYGRLARTMVIVAG-DYQGVAVVTDEVAYLDKFAVLPS-LQGE-GIVDFLWGALRDEDLVWRSRMENPVNKWYWERSSGFSLFWIPSCW CryneH991 LQ-A-SPSARDSRSYLSSVKIQGPTDAQLSICRGMAHLQKLGLVSVIVVDHEVERVVHFLSGEIPVLLPVAPANRVLLALASRLLVINR-EGGILYINLASEFLSNLSLANGCLAHMPREASALIVPAALIANLITNKPASASL-PTLIRKGLPVVDQGKLTHLLETSFKRTLDRKGFYNRLKNDLVIVIG-DYAGAAVCTLEICYLDKFAVHPS-HQGD-GTVDFLWVALRDEDLVWRSRSDNPVNKWYYERSSGWKVFWIPSAW Crypa2 LESS-SATKRDAKLYLQTIKFRLPDDGTLGVAKTIAQLRALGLLSVVVLDEQIYRLAGAIDGSVAIVPP-VDPSNAVVSITRRVIVLDP-LGGIVFLNLEDELLKNLDLIKKTLAILPSTSSALITHNPLIHNLLTDRPSSSSL-PTLAKRGMPVVDLGRLVHLIDDSFNRKLDVQDYLHRVEKSLIIIAG-EYEGGAILTWEVPYLDKFAVLKK-SQGAGGVADIVFNAMVRDGVCWRSRKNNPVNKWYFERSRGWSMFWIQPSW Debha1 LK-S-TTTKREARNYLNKLFINRFQNPFTGMAETFKRLIHLGISPIIMLDKIMNILGKPTEGVIPIIQPIVDSNDLLFSLCSKVVMIDP-IGGIVFINLSQEYMNNLKAMNKTLTLVSDKTTGIITLNPIIYNVLTDRSISSSL-PSILKKGVDVVNKSKLVDLIDDSFGKKLDTEKYFDRINDSLVVIVG-DYDGAAIITWEIAYLDKFAIASV-NQGLPGLADIIFKIILQSELIWRSRKNNPVNKWYFERCCGWKIFYIPPSF Dekbr2 LK-S-TATKREARYYLKRIRIRNLSISTINIGETLSKCMRLGASPIIILESMNERCDRLVTGMIPVLSPWVNSLDIMKYTIKKIIFIDE-LGGTVLINLLQEYLRNLIDMNTLLSIATGA-TGILTTNPIIHNILTDRPTSSSL-PTIIKKGIPIIDLEKLQFLIEDSFGRKLDLKHYLERINGHILIIAG-NYEGCAILTWEIAYLDKFAVLKR-LQGLPGLADIVFKAMLVNELIWRSRKTNPVNKWYFDRSTAWRMFYIPPSF Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LR-A-NPSLRDTKSYLQFVKLQGPTDRQLSIATGLVYLEKLGLTSVIVIEDEVMRVVSALEGEIPVLPPLAHSNDVLGALAKRLMVINK-EGGVLLVNLTGEYLQNLALARTCLSYMPPSSSAIMVPKSLIGNLITNKPESSSL-PTILRKGMPILDREKLTSLLESSFRRTLDQDAYFRRLEKHLAIIAG-DYAGAAIVTNEITYLDKFAVRPE-NQGD-GTVDFLWVALHDEDLVWRSRADNPVNKWYFERSTGWVMFWIPSAW Fusgr1 LE-V-SATKRDAKGYLQKMKLRAPDTETLGVANTLSQLRKLGLLSVVVIDEQTFRLCEAIDRMMPVIPSVVDSNQIVLALTRRIILLDP-LGATRFINLEQEYAANLALAKDALAMLPHTSSALITKNPLLHNLLTDKPVSSSL-PTLLKKGMPLIELLRLVHLIEDSFGRKLDVDDYLNRVNENLVIIAG-DYEGGAILTWEVPYLDKFAVLRK-SQGSGGCADIVFNAMVRGGVSWRSRKDNPVNKWYFERSLGWTMFWVEPSW Galma1 LR-T-NPSLRDARSYLASVKIQGPTENQLSICRGLVYLEKLGLVSVIVVEDETMRIVTKLEGEIPVIAPFADANDVIAGLARRLMIIDR-NGGVLLINLTSEYLSNLALARTCLEYMPATSSAIMVPSSLIGNLITNKPASSSL-PTLLRRGLPVIDKTKMNRLLEESFKRDLDHDSFYKRLSKVLVIVAG-DYAGAAIVTKEISYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRSDNPVNKWYFERSSGWVLFWIPSSW Ganpr1 LS-S-APSPREARSFLKKVLVETGPRSELSFATTLVYLQKLGLTTIVVL-HEAFRVANVLDHQTPILTSLASSSISVSALAQRLIIVNS-RGGVSLVSLEEDYLRDLQLCKTVLSQLPPTSSAIIASPTLLYNILTDRPLSSSLPPTVVRTGVKVLDLPRLKELLEASFGKTLAADPFWDRLRSCMTLLAG-DYMGASIMTREVVYLDKFAAHPK-AQGS-GVADALWRRMDRMDWLWRSRADNPVNKWYFDRSDGWMVFWIPASF Gloin1 ------------MSYIKRIKVQGPTSLDLSISNTLVRLQNLGLMPIVVLDEDSANVCEALEGHIPIILPVAHPNSGMIALSRKIIVINS-EGGVVFINIQQEYLENFEMIKTCLEGLPSTTSAIMAPRGLINNLITDKPLSSSL-PTVIRYGMPVIDIPSLNSLIEASFGKKLDTKGFIDRMKKRLVIVTG-DYQGAAIVSME-PYLDKFAVSPN-NQGI-GIADILWKQLQIRNLMWRSRCNNGVNKWYFERSDGWMMFWIPPSF Hisca1 LS-S-ASTKREAQSYLSRVKIREPNDQTLEVGRTLSQLSLLGMSCCVVIDKQADRMLAAIEGKIAVIPPIGLADDVVLALTRRLIILDP-AGGIVFVNLEQEFLDNLTLLHNALTYLPPASSGIISRNPLIHNLLTDKPSSASL-PTFVKKGMPLIDLPRLVQLIEDSFNRKLDVQHYLNRVSDRLLIIAG-EYEGGAVLTWEVPYLDKFTVLKR-SQGAGGVADIVFNAMVRTGVCWRSRRDNPVNKWYFERARGWTMFWIEPSW Klula1 LN-S-TVTKREAKDYLNKVFLRHLSDNVLGFSKTVSRIQTLGLRPILIVDYQSQRLDNHLHHIIPIIEPYQDPSRFLSSLVSKVFLISK-YGGLVFVNLSQEYMEDLEIMNKTLSVLPHSSTGLITNNPLVYNILTDRSLSSSL-PTVFKKGIDILDLNKLNGIINSSFKRSLDLSHYLGRINGNIIIVIG-DYEGIAILTYEFVYLDKFAVAQK-LKGSLGISDIIFNLMFRKELIWRSREDNVVNKWYFQRSTGFKLFYITPSW Lacbi2 LR-A-NPSLRDTRSFLASVKIQGPTDVQLSITRGLVYLSKLGLVSVIVVDDEVMRVVSSLEGEIPVVSPFADSNDVIAGLVRRLMIINR-HGGILLINLSSEYLSNLALARTCLAYMPPTSSAIMVPSSLIGNLITNKPASSSL-PTLLRRGLPVIDKIKLNALLEQSFGRKLDSASFYARLEKKLVIVAG-DYVGAAIVTNEISYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRSKNPVNKWYFDRSSGWVLFWIPSSW Lenti61 LR-A-NPSLRDTKSYLASVKIQAPTDRQVSIARGMVYLEKLGLVSVIVVEEETMRVVNALEGEIPVLAPFADANDVIAALVRRLMIITR-EGGVLLINLTSEYLSNLELARTCLAYMPPTSSAVMVPSSLIGNLITNRPASSSL-PTLLRRGLPILDKAKLKTLLEQSFRRELEEDAFWKRMERDLVIVAG-DYAGAAIVTREITYLDKFAVLPK-HQGD-GTVDFLWVALHDEDLVWRSRADNPVNKWYFERSTGWVLFWIPSSW Malgl1 ------------------PSLQQP-------------------------------------GHIPIIMPMADADQVMVTLSRRLMVITR-EGGVLMINLSSEYLKNLAMIRDCLAYMPNMASGLIAPQSLIANLITNKAASPSL-PTVVRAGMPILDLARVQNVLESSFQRKLNADAYFARLKTHLVIVTG-NYDGIAIVTREIAYLDKFAMLPT-LQGS-GAVDFLWNALRDEDLVWKSRAVNKVNRWYFERSNGWYLFWIPSAW Mellp23 LQ-A-HPSARDSRVYLKSVKIQGPTDRQLSIVDGIIYLKTLGLVPIIVIDHESNRLADMIESEIPVISPVASADDAVKALAARLMIINR-EGGILSINLASEYLASLKLARTCLSYLPNEASALIVPKSLIANLITNKPASPSL-GTLIRKGLPIVDQMKMTELLEASFRQKLNRSAFYDRLSQTMVIIAG-DYQGIAVVTDEIAYLDKFAVLPS-LQGE-GIVDFLWGALRDEDLIWRSKVSNPVNKWYWERSNGFSLFWIPSCW Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MG-T-LPSPREARQFLSKIKLEGPDKDGLGVANTLVQLQRLGLMSVVMLDKDMTDIVEEIERQIPVMIPMAQSNKALVALAKRLIVINT-TGGICFVNLKDEYRSDLDMIKESLEHLPPTCSALI-SLTLITNLITDKPLSSTMRGTVLRSGLDILDLKQLQVLLESSFGKSLDAEGFYDRIKDRTVILAGKDYMGAAIVTREVAYLDKFSVAPK-SQGI-GVADILWKKLTDEDLVWRSRSDNPVNKWYFDRADGWTVFWIPASF Mucci2 ------------------TKVEGPDKNDWKVGNTLYKLQKLGLSSIVVPDSESMTLVESIENQIPIVVPILNANQAVVALTQKIVIINK-EGGISLVNVQEEFLADLAMVRDCLEQLPTSSSAIIAPSALITNLVTDKPLSSSL-PTVLRHGIKILNLPRLTALLEASFQKKVDTDAFYGRLEHVLAIIAG-DYEGAVIMTNEHAYLDKFAIAPS-SQGI-GLTDILWKRMCDRELLWRSRKDNGVNKWYFERSNGWVLFWIPASF Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LE-S-SATKRDARGYLQTVKLRAPDDVLLGVAKTLTRLRDLGLLSVIVLDEQTDRLLRAIGGHILVVPPRADANDIVIALTTRVIVIDP-LGGIVFINLEDEFLENLRLAKSTLALLPSNASVVMTRNPLIHNLLTDRPISSSL-PTLAKRGLPVIDLPRLVHLINDSFGRKLNVEHYLDRVKDSLIIIAG-EYEGGAILTWEVPYLDKFAVLRK-SQGAGGVADIVFNAMVRDGVCWRSRKDNPVNKWYFERSRGWAMFWIAPSW Orpsp11 LS-T-VPSKREAQHFLDTVKIPSFTDEELQIGSTIVQLQHLGLMPIIFVDNEAIRISNIIEHQVPILIPIVDFDRTMISFSKKIIVLNN-NGGIGFINLANEYLYELQTMKIILSNLPVNTSAIIATPSIISNLITDKPISDNI--TLIRQGLKIINRKKLLNLLNSSFKKPIDTEHYFKRLEKVLITITG-DYQGASIITREVPYLDKFAVSPD-SQGI-GVADILWKRMKHDNMLWRSRAENPVNNWYFERSSGWRLFYIPASF Pench1 LS-S-ASTKREAKSYLARIKITTPDNSVIGVAKTLSQLVRLGMACCVVVDEQANRISAAVDGHVVLVPPIASANDAALALTKRVIVLDA-LGGIVFINMEQEFLENLRLAQQALAMLPSASSGIITRNPLIHHLLTDKPLSSSL-PTFVKRGMPLIDLPRLVTLIEDSFDRKLDVQNYLERVNSRIVIVAG-EYEGGAILTWEVPYLDKFAVLKR-SQGAGGVADVVFNAMVRTGVCWRSRMDNPVNKWYFERSSGWAMFWIQPSW Phybl2 MK-T-SPSKRELQHFLKRTKVEGPDRTGWAVGSTLLKLQKLGMTSIVVADRESMALVEAIENQIPVVFPILKANEAMVALTRRIVVINN-EGGISLVNVQEEYIQNLDMVKDCLSCLPTTSSAIIVPKALIANLVTDKPLSSSL-PTVLRHGIKILDLPNLTRLLEASFQKKIDQSSFYARLERDLAIIAG-DYEGAVLMTREHYYLDKFAIAPT-SQGI-GLTDILWKRMCDAELLWRSRQDNGVNKWYFERSNGWVLFWIPASF Picst3 LK-S-TTTKREARNYLNKLFVNRYQNPFIGIAETFKRLVNLGISPIVFLDKVMNYLGKPEEGIIPFIQPIINSNQLLYSLCEKIVMIDP-IGGIVFINLSQEYLANLNTMHEILTLASSKSTGIITINPIIYNVLTDRPISSSL-PSILKKGVDVVDKNRLVALLDDSFGKNLDTDSYFDRINNSLLVIVG-DYDGAAIITWEIAYLDKFAIAKK-NQGLPGLADVIFKIILLSELIWRSRKVNPVNKWYFERCVGWRIFYIPPSF Plicr1 LR-A-NPSLRDTRSYLASVKLQGPTEVQLSIARGMVYLEKLGLTSVIVVEEETMRVVTNLEGEIPVLPPFADANDVIAALARRLMIINR-EGGVLLINLTSEFLKNLSLARTCLAYMPPTSSAVMVPSSLIANLITNKPASSSL-PTLLRRGLPIINRAKMTTLLEHSFGRVLNEESFYKRLEERLVVVAG-DYAGAAIVTNEVTYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRANNPVNKWYFERSSGWVLFWIPSSW Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LE-A-HPSARDSRLYLKSVKIQGPTDRQLSIVDGVIYLKTLGLMSIIVLDRETGRLSAMLEQEIPIIPPIASADEVVKSLAKRLMIINR-EGGILSINLASEYLANLSMAKSCLKYLPNESSAIIVPKSLIANLITNKPASPSL-KTLIRKGLPILDLTKLKDLLEKSFKKTLDHQRYFERLKNSLVILAG-DYQAAAIVTNEIVYLDKFAVLPS-LQGE-GIVDFLWGALRDEDLVWRSRTDNPVNRWYFERSNGFSLFWIPSCW Punst1 LR-A-NPSARDAKLYLASVKVQGPTDRQLSIARGIVYLEKLGLLSVIVVEEETMRVTRALEGEIPVLPPMANANDVVAALARRLMIINR-EGGILLVNTTAEYLANLSLARTCLSYMPPSSSAVMVPSSLIANLITNKPASSSL-PTLLRRGLPIIDKAKMKNLLEQSFKRTLNEYSFWSRLERDMTIIAG-DYAGAAIVTNEIAYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRADNPVNKWYFERSTGWVMFWIPSVW Rhior3 MD-T-TPSKRELEHFLKRTKVEGPQKSGWKVGKTLYTLQKLGLTSIVVSDRESMALVEAINNHIPIVLPVLKATDAVLALSQKIVVINK-EGGISLVNLTEEYLENLTMIQSCLKGLPVTSSAVITPSTLIANLITDKPLSSSL-PTVLRQGTKILDLTKLTELLESSFRKQVDFDGFYSRLEHVLAIIAG-DYEGAVIMTNEYAYLDKFAIAPF-SQGI-GLTDILWKRMCDAELLWRSRKDNGVNKWYFERANGWVLFWIPPSF Rhoto1 LE-A-HPSARDSRFYLRNVKVQGPTDRQLSIAEGMVYLKKLGLVSIIVMDRETIRFSDMLEGEIPVIPPIASANDAVRAIASRLMVINR-EGGPLSINLESEFLSNLALIRDCLADLPRTASAVIVPRSLIANLITNKPASPSL-ATIIRRGLPILDEDKLAHVLEESFGKTLNREPYYDRLRRDLCIIAG-DYQAVAIVTNEIAYLDKFAVLTS-LQGD-GTVDFLWGALRDEDLVWRSRSNNPVNKWYFDRSTGFALFWIPSCW Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 LN-T-TATKREAKDYLSKFFIRDLAPAILQFSSVIKRLGMLGLRPMFVIPIQAELLDSIVTNFIPIVKPYVDVVKFMDCLCQKFFILNN-AGGIVFINLSQELLENLLLMDKVLSNLAATATGLITKNPLVYNLLTDRSLSSSL-PTVLKKGVHILDINKFKSIIDQSFKRSLDLHDYIKRINGKIIIVIG-DYEGIAILTYEFVYLDKFAVLPH-LKGSLGISDIIFNLMFKKEILWRSRKDNVVNKWYFQRSVAFKLFYIKPSW Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LR-A-NPSLRDSKNYLASVKMQGPTDVQLSVARGLIYLKKLGLVSVIVVEEETMRVVRALEGEIPVISPLADANDVIGALAKRLMIINR-EGGVLLINLESEYLSNLALARTCLTYMPPTSSAVMVPSSLIGNLITNKPASSSL-PTLLRRGLEIIDRSKLTALLQQSFGRELDANAFYSRLEKTLVIVAG-DYVGAAVVTREVTYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRADNPVNKWYFERSSGWVLFWIPSVW Schpo1 LK-S-VQSRRSTKGFLQKTKIDDVSDNTLGIGRSINSLARLGIQSVIVPTQQQNRVIRVSELYTVIVPSSIDGNEVLAGLTYRIVILDK-NGGMVLINLAQEFRKNLILVRRCLKMLPDDASALITKNPLIHNVLTDRSISCSL-PTVLRSGVPVVSWERLWVLINDSFKRTLDMDAYLDRLKNSLVIIAG-DYLGTAIVTYEVPYLDKLAVSQG-AQGSAAISDVMFNVMT-DELIWRSRLTNPVNKWYFERSVGWKLFWIQPTW Sorma LE-S-SATKRDARGYLQTVKLRAPDDVLLGVAKTLTRLRDLGLLSVIVLGEQTDRLLRAIGGHILVVPPRADANDIVIALTTRVIVIDP-LGGIVFINLEDEFLENLRLAKSTLAILPSNASVVMTRNPLIHNLLTDRPISSSL-PTLAKRGLPVIDLPRLVHLINDSFGRKLDVEHYLNRVKDSLIIIAG-EYEGGAILTWEVPYLDKFAVLRK-SQGAGGVADIVFNAMVRDGVCWRSRKDNPVNKWYFERSRGWAMFWILPSW Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 LS-T-LPSQREARHFLKRIKVDASTEVELAFAGTLVQLQKLGLTPIVVIEEDLFRVVEAIDNQIPVLAP-LTSRDALVSLSAKTIFVNH-RGGFGFVNLEDEYLDDLETVRTVLSVLPSSSSAIIA-ASLISNLITDKPLSTSFDPTVLRQGLRVLDLRRLQVLLEASFQKSLEADAFWKRMDNVMVILAG-DYDGAAIVTNEIAYLDKFSVAPT-SQGI-GVADILWKQLRKRDLSWRSRAANPVNKWYFDRSDGWVLFWIPASF Sporo1 LE-A-QPSARDSRFYLKNVKVQGPTDRQMSIAEGMVYLKKLGLVSIIVMDADTLRFSDMLEGEIPVIPPIASANDALRAISHRFMIINR-EGGILSINLESEYLANLALVRDCLADLPRTASAILVPRSLIANLITNKPASPSL-HTIVRRGLPIIDQDKLTYVLEESFGKTLDREPFYDRLRRDLCIIAG-DYQAVAIVTNEIAYLDKFAVLPS-LQGD-GTVDFLWGALRDEDLVWRSRSNNPVNKWYFDRSNGFALFWIP--- Stehi1 LR-A-NPSTRDAKSYLSHVKVQGPTDRQLSITRGIIYLAKLGLVSVIVVENEVMRVVGAFEGEIPVLAPMADANDVVAALARRLMIINR-EGGVLLINLASEYLSNLALARTCLSYMPPSSSAVMVPSSLIGNLITNKPASSSL-PTLLRRGLNIIDKVKMTALLEQSFNRTLEADEFYKRLESDLVIVAG-DYAGAAIVTREIAYLDKFAVLPS-HQGD-GTVDFLWVALHDEDLVWRSRANNPVNKWYFERSSGWVLFWIPSSW Tapde11 LA-A-TATKRDAKAYIEKITIRDMTTEQLRIADTLAQLHRLGLQPVVIVDKQVERLTSILHRQIPVIRTLATADSAMKALCKKLIIIDK-VGGIVFINLDQEALRNLDTCQVCLDLLTDSASAVVTQHPLIYNLLTDKPMSPSL-PTILRKGVSVINLTKLVSLIDDSFGRRLDVEGYLARLGDTVVIVAG-DYEGAAIVTSEVPYLDKFAVLRA-RQGAGGVADVLFNAMMRQELTWRSRDENPVNKWYFERAKGWRLFWIQPTW Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LQ-A-SPSVRDSRSYLSSVKIQGPTDPQLSIAKGMARLQKLGLVSVIVIDREMERVVDFLIGEIPVLLPVAHSNLVLTALAKRLLIINR-EGGILSINLSSEYLSNLSLAHTCLRLMPREASALIVPAALIANLITNKPASISL-PTLIRTGLPVLDIEKLTNLLETSFRRKLNGEKYWERMKKDMCIIIG-DYAGAAIVTSEICYLDKFAVHPE-HQGD-GTVDFLWVSLRDEDLVWRSRSDNPVNRWYFERSSGWKVFWIESAW Trire2 LE-S-TATRRDAKGYLQKVVLRNPRPDTIGIAKTLTQLRVLGLLSVVVVDSEALRLCEAVDDMIAVIPSLADAQRTTLALTRRVIVLDS-HGGTRFVNLEQEYAKNLKLAKDTLSLLPETASVLITQNPLLHNLLTDKPVSPSL-PTLVKRGMPLIDLQRLVALIEDSFGRKLDVDDYLQRTNQNLVIIAG-EYEGCAILTWEVPYLDKFAVLRS-RQGSGGVADIIFNAMVRDGVLWRSRKDNPVNKWYFERSVGWAMFWIMPSW Umbra1 MS-T-VPSQRELRHFLKRTKVQGPAKRGWAVASTLIKLKRLGLTSIIVLDLESMALVESIENHLPVIIPIITADEAMITLSEKIVVINH-EGGISLINIEEEYIENLAMIQSCLENLPSTSSAIITPSALITNLITDKPLSSSL-PTVLRHGTSILDLDKLTVLMEASFRKKLDRDAYYDRLGNVLAIIAG-DYEGAVLVTNECSYLDKFAIAPQ-SQGI-GLTDILWKKMYDAELMWRSRKDNGVNKWYFERSDGWVMFWITASF Ustma22 LQ-A-QPSLRDSKTYLNSVKVQGPTDRQLSIAEGLVYLKRLGLVSVVVVDAETLRLADSLNDQIPVLAPYARADDVMVALARRLMVINR-EGGILSINLASEYLRNLDAISDCLSYMPQTSSGVLVPRSLIANLITNKAASPSL-PTIVRPGLPILNLDKMCALLEASFRRKLNQHAYYERLRKSLAIITG-DYQGAAIVTKEIAYLDKFAVLPS-LQGS-GTVDFLWGALRDEDLVWKSRSNNPVNRWYYERSNGWQLFWIKGAW Walse1 LN-A-RPSARDSKSFLASVKLQGPTDRQLSIGFGMNHLRELGLVSVVVVDEEVIRVTETLIRITPVIPSFAHADEILVALSERLLIITK-TGGILSINLSSEHLTNLSLARRCLMNMPQSSTALIVAMELVANLITNKPASASL-PTSVRLGAPIIDQDKLTHLLESSFKRVLDREAFYGRLKKSLVIIAG-DYGGCAIVTNEIAYLDKFAVLPS-MQGD-GTVDFLWLALRDEDLVWRSRGNNPINKWYFERATGWVMFWIASSW Zygro1 LN-S-TATKREARDYLTKLLIRHLSQKNLKLSGTITRLRMLGLKPICVIPKQAESWDRLLSHLVPILRPYMESIQFFRGLCNKFFILNN-IGGIVFINLSQEFIEDLQLMNVVLSNLSNSSTGLITNNPLLHNLLTDRSLSSSL-PTVLKKGIHILNLTKLKRILDQSFGRELDLKHYMNRVNGRIVIVIG-DYEGIAILTYEFVYLDKFAVMPH-LKGSLGISDIIFNLMFKLELLWRSRRDNVVNKWYFQRSVAFKLFYIKPSW [Cluster2957.fasta_al_trimmed; alignment length = 79] Allma1 ------------------------------------------------------------------------------- Ashgo11 EMEASIEEKFLHGGRGPGGQKINKCN-SKVQLRHVPSGIVIECQATRSREQNRKLAREKLAAALARQGKHAQARKSREK Aspfu1 IDDADLTVSYLKG-TGPGGQKINKTN-SAVQLIHKPTGIVVKSQATRSRSQNEKIARQILADKVERKKKASKMKKTRRK Aurde31 LNEDDLDEAFVRG-SGPGGQSINKTR-NCVQLTHRPTGLRVDCQMTRSLADNRRIARIWLLRKLDKERKRQKMKKKRKA Batde5 LVETDLVEKFTKG-SGPGGQKINKCK-HSVQLWHTPTGLFVETQRFRELASNRREARKLLLLKLDHRRVAKQKQRSKKK Botbo1 LREDDLEESFVRG-FGPGGQAINKTA-SSVSLIHKPTGIRIQCQQTRSLQINRHIARKILVEKLDRERKRRKQKKSNKK Botci1 VNGREEVERCTNG-SGPYG-VVNATRIAFIQLKHIPTGMVLKVQATRSRTQNRKIARQMLAERLEKKRKSSAVKKSKRK Caeel ------------------------------------------------------------------------------- Canalb1 IKEEDIEEKFLHGGRGPGGQKINKTN-SKVQLTHIPTGMVVSCQATRSQEQNRAIAREKLALKLDQKVKQSKSKKSNRK Cangl SMEADIEEKFLHGGTGPGGQKINKCN-SKVQIKHVPSNIVVTCQATRSRDQNRKIAREKLALELERQQKRSKGKKSRLK Capow LLESDLEEKFIKG-GGKGGQKVNKST-NGVFLRHLPTGIAVRCHMHRSLAQNQKQARKQLCELVNRMRRAKRELKARHN Catan2 LNEDDLDEKFIRG-GGNGGQKVNKTS-NCVVLTHRPTGIQVRCHETRSLSDNRRIARKLLKQRLDRRKKLKRQQKNKKG Cioin ------------------------------------------------------------------------------- CocheC53 LDESDLIENFLKG-SGPGGQKINKTS-SAVQLKHIPTGIVVKYQDTRSREINRKMARRILQDRIESKKKASAAKKSKRK Coere1 LQDADIEERHVRG-WGNGGQKLNKTS-SCVQLLHKPTNTMVVCQDTRSLQQNRKIAYKRLKDKLDRARKHKQRQRAKKK Conco1 LKEEDLRETFVKG-SGNGGQAINKTN-SNVELVHLPTGIRLQCQKTRSQSENRKIARKMMMQKLDKKQKAKSRKRALEK Conpu1 LKEEDIEESFVRG-SGPGGQSINKTE-NNVQLLHKPTGIRVSCQETRSLQTNRMLARRRLTEKLDRERERRRRKKAKKR Copci LKEEDLEESFVRG-SGPGGQSINKTE-NNVQLLHKPTGIRVSCQETRSLSQNRKIARKRLLEKLDRERERQRRKKAKKK Croqu1 IPESDLIEDFVRG-SGPGGQSINKTN-ISVSLIHKPTGIRVQCHAQRSRESNRKEARKILREKV--------------- CryneH991 IAEDELEERFVKG-RGPGGQAINKTN-SSVSLTHIPTGIRVQAQPTRSREENRKVARRILAERLERRRKANRAKKAKKK Crypa2 PPDEEITEAYLKG-SGPGGQKINKTN-SAVQLKHIPTGIVVKCQETRSREQNRKLAREHLAEKIDAKKKASALKKSRRK Debha1 IVEEEIDEAFLKGGRGPGGQKINKSN-SKVQLTHKPTGLVVTCQYSRSQEQNRKRAREILALKLDTKTKQGKTKKANKK Dekbr2 LPENELKEKFIKGGSGHGGQKINKTN-SKVQLTHVPTGIVISCQATRSRDQNRKIARQILALKVDKIRKQRAKRKSKAK Dicdi ------------------------------------------------------------------------------- Dmel LQESDIEETFMRG-SGPGGQAVNKTS-NCVFLRHLPTNITVKCHTHRLASKNRVEARKLLLEKLDRKSTERRRRQEKLQ Enthi ------------------------------------------------------------------------------- Falba LRDEDLQEQFVRG-FGNGGQKVNKTS-SCVILSHAPTGIVVKCQKTRSREQNRKEARKILIGLLDRRRKSRADRRSRAK Fomme1 LNEADLEESFVRG-SGPGGQSINKTS-NNVQLLHKPTGIRVTCQETRSLQTNRMIARRNLIEKLDVERERRRRKKAKKK Fusgr1 PPESEIEESYVKG-SGPGGQKINKTN-SAVQLKHVPTGIVVKSQATRSRDQNRKHARELLAQRVDEKKAASASKKSRRK Galma1 LREEDLEESFVRG-M--GGQSINKTE-NNVQLLHKPTGIRVSCQDTRSLSQNRKIARKWLLEKLDRERERQRRKKAKKK Ganpr1 LVESDLEETFVKG-TGPGGQKINKCR-HRVQLLHLPTGIRVQCQASRSLAINRAQARKLLLAKLDRRKKAKKRREAAGK Gloin1 LNEQDLIESFVKG-SGNGGQKINTTS-NCVDLKHIPTGIRVQCQKTRSLQQNRNIARKILIEKLD-------------- Hisca1 LDLSEVTGSYLKG-TGPGGQAINKTN-SAVQLIHKPTGIVVKSQATRSRTQNQKIAMGILAEKVEKKKKASREKKARRK Klula1 DMERDIEEKFLHGGRGPGGQKINKCN-SKVQLRHVPTGIVVDCQATRSRDQNRKIAREKLALRLAQQSKRSKERKAKSK Lacbi2 LREEDLEETFVRG-SGPGGQSINKTE-NNVQLLHKPTGLRVSCQDTRSLSLNRKLARRWLLEKLDRERERRRRKKAKKK Lenti61 LKEEDLEESFVRG-SGPGGQSVNKTE-NNVQLLHKPTGIRVACQETRSLKQNRKLARRILLDKLDIERERRRRKKAKKR Malgl1 LDERDIRERFIRG-SGPGGQAINKLS-TNVELVHIPTSTRITCQLTRSRAQNRELARRQLSQRLERKRKQNKRKKQRRR Mellp23 LNESDLIEEFVRG-SGPGGQCINKTNFISVSLIHKPTGIRVQCHAQRSRESNRKEARKILSEKVDRDKKRAKIRQRKRR Mnele -----------------------STR-NKVVVKHTPTNIVVQCHDTRSLEQNKNIAIRRLTEKVEEERKQAKKEEAAAR Monbr ------------------------------------------------------------------------------- Morel2 LLETDFRERFIKG-GGNGGQKINKTN-SNVELKHFETGIVVQCQATRSLPQNRKLARRILVERLDREKKKRMARKSAKK Mucci2 LKDEELVETFVKG-SGPGGQCINKRS-SCVDLRHIPTGIRVQCQQSRSLADNRGIARKLLREKLDAKQKARRARRAKEK Mydma LKESDFQEKFIKG-SGPGGQKINKTS-NCVELKHDATGIIVKCQETRSLERNRVIARERLLEKLRQKQEKNIERKRRLR Neucr2 PED-ELEEVYLKG-SGPGGQKINKTN-SAVQLRHIPTNIVIKCQETRSRTQNRKLAREILAAKVDKKKADSKAKKARRK Orpsp11 ------------------------------------------------------------------------------- Pench1 ISDADISISYLKG-TGPGGQKINKTN-SAVQIIHKPSGVVVKCQATRSQSQNAKIARSLLADKIEKKKKASKMKKTRRK Phybl2 LDDKELIETFVKG-SGPGGQCINKRQ-TMAKSNIFSSSMLLQCQQTRSLQENRGIARKLMREKLDSKQKARSARRSKKK Picst3 IKEEELDEKFLKGGRGPGGQKINKSN-SKVQLTHLPTGIVVTCQYSRSQELNRKRAREILALKLDTKVKQSKSKKANRK Plicr1 LREEDLEESFVRG-DGPGGQSINKTQ-NNVQLLHKPTGIRVTCQETRSLETNRMFARRLILERLDIERERRRRKKAKKK Polpo ------------------------------------------------------------------------------- Pucgr2 LDENELIEQFVRG-SGPGGQAVNKTN-NAVSLIHKPTGIRVQAHTHRSREANRNQARRVLAERH--------------- Punst1 LREEDLEESFVRG-HGPGGQAINKTN-NNVQLIHKPTGIRVTCQQTRSLDLNRRYARQILLDKLDNERERRRRKKQKK- Rhior3 LRDEDLIETFVKG-SGPGGQCINKRS-SCVDLRHIPTGIRVQCQQSRSLADNRGIARKLLREKLDVKQKARRAKRAKEK Rhoto1 LNEDDLDETFVRG-GGPGGQVTNKTS-NACSLIHRPTGIRVLCHETRSRETNRKLARRIMRNRLDRQKKAAKKRKAKKR Rozal11 ------------------------------------------------------------------------------- Sacce1 EMEAQCTEKFLHGGRGPGGQKINKCN-SKVQLRHEPTGIVVECQETRSREQNRKLARLKLARELARQQKRSQRRRSVAK Salro ------------------------------------------------------------------------------- Schco3 LREEDLEESFVRG-SGPGGQAINKTA-NNVQLVHKPTGIRVVCQETRSLEQNRKRARKIMIAKLDRERERRRRKKAKKR Schpo1 LQEEDIEETFICG-KGPGGQKINKTS-IVAQVKHIPTGIIVRSQDTRSREQNRCIARKRLTEKVDVKKKKQREKKSKRK Sorma PED-ELEEVYLKG-SGPGGQKINKTN-SAVQLRHIPTNIVIKCQETRSRTQNRKLAREILAAKVDKKKADSKAKKARRK Sphar VDEVDFEEQFVKG-NGPGGQKINKTN-SQVVLKHIPTGVVVHCQMGRSQAQNRKEARKLLALKVTKKRKADKLYKQAKK Spipu1 LNETDLEESFVKG-SGPGGQKINKCR-HRVQLKHVPTGIMVESQRFRELAANRKEARKLLRLKLDQKRKKRQAQKSKKK Sporo1 ------------------------------------------------------------------------------- Stehi1 LKESDLEENFVRG-SGPGGQSVNKTE-NNVQLLHKPTGIRVTCHETRSLEQNRTIARKKLLNQLDAERERRQRRKQRKK Tapde11 ------------------------------------------------------------------------------- Thetr VAEDELEETFLHG-SGPGGQKINKTQ-SRVRLVHAPTGLTVVVQDTRSREANRTIARKRLADKVERRRKAKAAARARRK Treme1 IPESDLEERFDKG-RGPGGQAINKTN-SAVSLIHLPTGIRVQAQPTRSREENRKAARRILAEKLERRRKANRAKKSKKK Trire2 PPDSEIEESYLKG-SGPGGQKINKTN-SAVQLKHIPTGIVVKSQATRSRSQNRKLAREILAQRIDKKRADSAAKKSRRK Umbra1 ------------------------------------------------------------------------------- Ustma22 ------------------------------------------------------------------------------- Walse1 LNEEDLLEKFVKG-QGKGGQAVNKTS-NKVFLLHKPTGLSVECHATRSLISNRSQARKLLQDKYDQKSKKNAMKKSRKK Zygro1 SLESQCEEKFLHGGRGPGGQKINKCN-SKVQLKHLPTGIVVECQQTRSRDQNRKIAREKLALEI-QQSKKSKERKAKGK [Cluster2961.fasta_al_trimmed; alignment length = 154] Allma1 RAFSTSSNIGRQPIAYDANSVEITVNVKGPLGTLTRDLMPFVRLLSVNVDF-QRAMWGTSRALLANVKGVTQGLKLVGVGYRAAVVQLKLGYANTVVIPIPVEAKCPAPDQIELTGIDKMLVNQFAATIRSYKPPEPYNQKGIFVNGETIKKKA Ashgo11 RLLSASSHIGAAPLYL-LPENKLSVTVEGPLGSASMELPDFVSLVAVTVHD-QRAMWGTVRSTLGSVQGVNEGLKFVGTGYRAALVSVKVGASIRQGLPVPVTVKSPAPTLLIIEGCVKQQVNLFAASLRMFHPPEPYKGKGIYMNNETIKLKD Aspfu1 QCFSTTSRVGGAPISI-PPEVSLKIEVKGPLGELTLNIPPFVEVASLTVQD-QRAMWGTMRAHLQNVLGVSEGLSLVGVGYRASIVSLKVGYSHPIELGVPVKASTPQPTRILLEGVDKNVVTQFAAEIREWRKPEPYKGKGIFVNGETIRLKA Aurde31 RVMSATSHIGKQAIPL-PAGVTIALTVTGPRGTTSLPVRRYVKLLRVSVAD-QREMWGLTRTLVANITGMTEGVHLVGVGFRAAVLQMKLGYSHSVFVPVPIKVECPFPTRIMVSCDNKQKLGQFCAEIRRWRVPEPYKGKGVFVGNEVVRIKS Batde5 AGFSFTSRIGAKPIKC-PAQVTFSITVKGPKGQLSMPIKPYVSILTVAVDT-QRAMWGTTRNLIQNVIGVTDGVRLVGVGYRAQLLVVRLGYPHPVIFHVNVQVSVPAPQRIILQGIDLHAVTAFAANIRKWRKPEPYNQKGVFVGDETIKKKD Botbo1 RNLASSSHVGSAPIPY-PPTLSL-LNLTGPKGTYTLPLAPFVNLITVSVED-QRATWGLTRALIANVQGLTEGLRLVGVGYRAAILRLKLGFAHDVVINVPIKAEVPAPTKIVLKGTDKHVLGLFAAKIRKWRKPEPYKGKGIFVGDETIRLKD Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 RLFSTSSNVGKKPIRL-YEGVNYSIITSGPLGKLRVEIPEFINIIIVSVKK-QRSLWGTYRSILYNIIGITEGVKFVGTGYRAILISLKIGLPFTPKLKIPLKVSSPNPARLVIEGSDKQQVKLFAAFIREHKKPEPYKGKGIFVDDEKIVLKQ Cangl RAFSVSSHVGSMPIYV-APEVNVSISVEGPKGTLKLEVPDFISMVTISVKD-QKSMWGTVRSLVNNIVGVTEGLKFVGTGYGARLVNIKVGASIKQGLDVPITVKSPSLTSLIIEGSDKQQVLLFAAKLRDFHPPEPYKGKGIYVNGETIKLKA Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 RCFSTGSNIGRQPVTFDPAAVSVHVTVTGPLGQLSREVPAFVRILSVNVEF-QRAAWGTTRAHLANVKGVTQGLRLSGTGYRAMLLQLKLGFANTIELPLPVTAKLPAQDQITLTGADKDTVAQFAATIRAYKPPEPYKMKGIFVNGETIQQKE Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RSFTSTSKIGSAPLSI-PQGVTFKVHIKGPLGELSMDIPPYINIPTLSIED-QRAMWGTTRAYLQNILGVSEGLRFVGVGFRASVINLKVGYSHPVELGIPVTASTPQPTRLLLEGPEKEVVMQFAAEIRNWRKPEPYKGKGIFVNGETIKLKN Coere1 ------SHIGSLPIKY-TSEVKIELKVIGPLGERTMAIEPYVKLLHFSVED-QRQMWGTTRALVNNVIGVTEGLRFVGVGYRAAILVLRLGYANPVNIEIPLSVTVPVPVRVLISGTDLQQVKLFAAKIRAWKKPEPYKQKGIFINDETIRKKE Conco1 RGFSTASHIGKASLYY-PSDVTISLSVKGPLGEQRVPIVPFVKLLKVTVED-QKAMWGTTRALISNIEGVTEGLRMSGVGYRAMLIGLKCGYSHPINEPIPIQVKIPNPTKIIMTSIDKQKLMAFATKVRKWKKPEPYNGKGIFIGDEVVRRKE Conpu1 RHFSSTSHIGKAPINV-PQNVTLTVTVTGPLGTTSVPLDPFIRLLNVAVED-QRAMWGTTRTLINNVIGMTEGLYLVGVGYRAILLNMKLGHCHVIYVPIPIKAEVPSPTKIVLSCNDKQRLGLFAAEVRKLRPPEPYKGKGVFIGDEQIRIKA Copci RSFSTSSHIGREPIKY-SPEVTLTLSVKGPKGTTAVPLHPFVQLLSVSVED-QRQMWGTTRTLIANITGMTEGLYLVGVGYRASLLKMKLGHSHFIHMEVPIGIEVPNATKLVLSCTDKHELGLFAAKVRAWRKPEVYKGKGVFIGNEQIRLKS Croqu1 RTFSSTSHIGSKPVPV-PSSISLSLTVTGPLGKLSIDLASFVRLINVTVED-QRGTWGLSRALLANVSGVQTGLTLVGVGYRASLLNLRVGYSHPVLIDLPLGCELPSPTEIVIKGIDKQELGLLGASIRKWRPPEPYNGKGIYLNGETIKRKE CryneH991 RQIHSSSQIGKVPIPI-PPSVVLTFTVSGPLGSATLPISPSVILLTISVHD-QRSVWGLTRTLINNVTGVSAGVKLVGVGYRATILNIKLGFAHPVLIDIPIKVTVPEPTKIMLNGADKQKLGQFAATIRQWRKPEPYRGKGIFVGGETIRLKE Crypa2 RQFSVSSKLGRTPISI-PPGVELTVSVAGPLGKLDLNVPMFLKLLVIGIED-QKAMWGTTWAYIQRIIGVSEGLRLVGIGYRASIVCLRLGFSHPVDLGVPIKASTPQPTRILLEGINREQVMQFAAEIRRWRVPEPYKGKGIFVNDETIKLKQ Debha1 RPFSSSSNIGKQPITI-TEAVQCYIVVKGPKGVLKTAVPEFVQVITVSVEN-QRTIWGTSRALVQNIIGTTEGVKFVGTGYRATIIALKIGYPYTPKLKVPLTVSSPNPARLLIEGSDKQQVKLFAARIREHKKPEPYKGKGIFVDGETIKLKE Dekbr2 RSFSTTSHIGSSPVFI-SNDVQLQLTVKGPKGAVNLELPDFVTIINVNVAN-QKSLWGTSRSLVNNVVGVTEGLRFKGTGYRVLVVKMKIGKCDMQGLPIPIKCSTPTSTLLVLEGCNKQSLNQFAGRLRNMHPPEPYKGKGIYMNGETIKLKA Dicdi MKYSQNYKIANKSVKI---------KSSGKMGVI----------KELKLKE-NNIYYGDSRIIIGTIQGVLAGLKLVGLGFVVHKLVLDVGYSHYRSCLIPVKLE---GSQIILYSINKEKVTTFASLLKTFKKINMYKGTGILGINEKIKLKK Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 RFFSTSSNVGRAPIPI-PQAVVLTITVKGPLGTTSVPLKPYVQLLSVGVEN-QRQMWGTTRSLINNIIGMTEGVYLVGVGYRAALLNMKVGYSHSVFVPIPIKAEVRLPTKIVLSCTDKHLLGLFAAKVRSWRPPEPYKGKGIFVGDETIRIKQ Fusgr1 APFSTTSKLGRTPLSI-PPGVELSINIKGPLGSLGLEVPEYVQLVLLSVRD-QKAMWGTTWSYLRNIMGVSEGLRLVGVGYRASVLCLKLGFTHPVEEGIPVTVTTPAPTRILIEGIDREVIMSFAGRVRMWRPPEPYKGKGVFINDQTIKLKQ Galma1 RCFSSTSIIGREPITI-PSSVTISVTITGPLGSTAIPLKDYMKIMKLSVEK-QRQMWGTTRTLISNITGMTEGIYLVGVGYRVALLNMKLGYSHSVLVPIPIKAEVPSATKIVLFCTDKHLLGLFAAKIRGYRKPEPYKGKGVFVGNETIRIKS Ganpr1 KTFSTSSKIGQRLLTF-PADVKISILVTGPKGEISFPLQPFVSVLQLSVLD-QKAMWGTTNSILSSITGVTEGLRLVGVGYRASIVDLKLGYSHPVLVDIPVTCTVITPQRLRLQGIDVQKVTQFAAQIRKWRPPEPYNQKGVFVGDETIAKKE Gloin1 -------------------------------------------------------MWGTTRALINNVIGVSEGVRFSGVGYRANMLVLRIGYAHPVIMDVPIKCITPSPTKVILSGTDKQRVFQFAANIRKHKPPEPYNQKGIFVGDETIKKKV Hisca1 QPFSVSSRVGSAPLSV-PSEVSLKVEVTGPLGSMTLTLPSFSTVATVEVQD-QRAMWGTIRQHLKNILGVSEGLKLVGVGFRAMIVSLKVGYAHPIELGIPVKASMPQPTTILLEGINKEVVTQFAAEIRAWRKPEPYKGKGIFVNGETIRLKA Klula1 RLFSVSSHIGSSPVYL-TPETKLVVTVSGPLGKIDMEIPDFVEIIEVAVKD-QRSMWGTVRSHINNITGVNESLKFVGTGYRAQLVNVKVGASVRQGLPIPIIVKSPVPTSLIVEGVNKQQVLLFAANLRKFHPPEPYKGKGIYVNNETIKIKD Lacbi2 RCFSSTSHIGREPIKY-PTKVTLTITIQGPLGTTSVPLQPYMKIVAVSVED-QRQMWGTTRTLISNIIGMTDGLYLVGVGYRVAILSMKLGYSHTVYVPIPIKAEVPSPTKIILSCTDKHLLGLFAAKVRGYRKPEPYKGKGIFVGNEQIRIKS Lenti61 RSFSSSSNIGKQPITI-PPTITLAVSVKGPLGETSVPLMPFMKLLAVSVEN-QRSMWGLTRTLIQNIVGMTEGVYLVGVGYRAALLNMKLGFSHPVFVSVPIKCEVPLPTKIVLSCTDKHQLGLFAAAIRRWRPPEPYKGKGIIVGNERIRMKT Malgl1 HVYHGSIHTRRKPITI-PESIKLSLVFNGPKGEVVVPLHHFVNMVTFAVEN-QRGIWGLTRALCANIKGAQDGLRLVGVGYRASILHLRLGYSHPVLVPIPVQAETPSPTTIKLSSANKELLGQFAQSVRQFRKPEPYKGKGVFINDEQIKLKT Mellp23 RTISSTSHIGSKPVPI-PATISLSLTVTGPLGKLSIDVASFVRLINVGVED-QRGTWGLSRALLANVNGVQTGLKLVGVGYRASLLNLRVGYSHPVLIDLPLGCELPSPTEIIIKGIDKQELGLLGASIRKWRPPEPYNGKGIYLNGEIIKRKE Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 RSFTTSSHIGKQTLPF-GSDVVMTLHIKGPLGEHILPIKPYIKLLSVSVED-QRAMWGTTRALIANVTGVTEGVRLVGVGYRAAILSMKLGYSHPVEIEIPIQCTTPLPNKIMLQGNNIQKVKEFAFKIRKWREPEPYNQKGIFVGDETIAKKT Mucci2 RQFHQASHIGRQPIAY-ANDVRIELTVAGPLGKLQLPIKPFVKILQVSVQD-QRAMWGTTRALINNIVGVSDGLRLVGVGYRGMLLSLKLGYSHPIQMELPVTCSVPAPNRIVLQGVNLQHVTEFAAKVQRWRMPEPYNQKGIFINDETIKKKE Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RNFSATSKLGRTPLSI-PPGVEITITVQGPLGQLEMDIPDFIKIATLSVAN-QREMWGTTWAYLNRIMGVSEGLRLVGIGYRATIVCLKLGFSHPVEMGVPMKASTPQPTRILLEGINREQVMTFAADIRRWRVPEPYKGKGIFVNGETIKLKQ Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 QCFSTTSRVGGAALSI-PPEVSFKAEIKGPKGEMSLNIPSFVNIASLSVED-QRAMWGTVRALLQNILGVSEGLSMVGVGYRATIVSLKVGFSHPIELGIPVVASTPQPTRILLEGVDKRIVTQFAAEIREWRRPEPYKGKGIFVNGETIKLKA Phybl2 RALSTSSHVGRKPIAY-AQEVSIELTVRGPLGKQQLAIKPFVKLLEVGITD-QRSMWGTTRALINNIVGVSEGLRLVGVGYRGTLIALKLGYAHPVNIELPVTCSIPQPNRLILQGVDLQQVTELAACIQRWRKPEPYNQKGIFINDETIKKKE Picst3 RAFSQTSHIGKLPIKL-SESVQCTVVIKGPKGVLKTAVPKFIQVISVTVEN-QRSMWGTVRSLLQNLIGTTEGVKFVGTGYRGILVSLKIGLPYTPKLAIPLTVSSPGPTRLVIEGTDKQQVKLFAAVIREFKKPEPYKGKGIFVDDETIKLKE Plicr1 RQFSSTSHIGRAPIPI-PPTVTLAITVTGPLGTTSVPLETYMTLLALTVAD-QRSMWGLTRTLIHNVVGMTEGLFLVGVGYRAALLNMKLGYSHSVYVPIPIKAEVPHATKITLSCNDKHQLGLFAASVRSWRKPEPYKGKGIFIGNETIKIKS Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RQFSVTSHIGSKPIDI-PPEVTLSISVKGKLGKLDVDVLPFVTFLKVNVAD-QRGIWGLTRALMANVHGVTEALELVGVGYRASLLNLRVGYSHPVLINLPLSCEVPSPNRILLKGIDKQELGLLGAGIRKWRPPEPYNGKGIYLNNEIIKRKE Punst1 RAFSSSSNIGKKPIPL-PPSITLTLAVSGPNGTARVPCEPFVRLLEVRVDD-QRTMWGTTRSLIANVTGMSEGLYLVGVGYRAALLNMKVGFSHSVYVPIPIKAEVPMPTKIVLSCTDKQKLGLFAAEVKKWRPPEPYKGKGIFLGNETIRIRA Rhior3 -------------------------------------------------------MWGTTRALINNIVGVSDGLRLVGVGYRGTLLSLKLGYSHPVLMKIPLTCTVPQPNRVILSGVDLQQVTEFAAKIQRWRKPEPYNQKGIFINDETIKKKE Rhoto1 RPFSSSSHVGSNPIPL-PPAVSFEARVRGPKGELLVPIHPFVRLLTVSVDD-QRAIWGLTRALLANVKGVSEGLRLVGVGYRATVLNLKLGYSHPVLIDLPISAATPAPTSILLTGIDKQRVGQLAAKIRKWRVPEPYNGKGIFVGDEQVRRKE Rozal11 RELSPLSFIGAKPVII-DSRIKYRIVFEGPLGKLGVQIPEGLNVFYYRLKSFVRSMFGTCRQLMEQAYGVLDGLTLVGVGFRASVLDLRLGFCHPVIIKIPIKVEVPFPTRIIVSGITMGKVKNFAAIIRSKYKPEPYKGKGIYIGEEKCYMKK Sacce1 RLLSQTSQVGSLPLYI-SPEVQVSITVKGPKGELSVEVPDFLHLINVTVQN-QRSMWGTVRSLINNIIGVTEGLRFVGTGYRAQLVNVKVGASIKQGLDVPIVVKTPAPTSLIIEGCNKQQVLLFAAKLRKFHPPEPYKGKGIYVNDETIKLKD Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 RRFSTSPHIGREPLLW-KDPVKLTILVEGPLGRTAVPLKPYITLLQIGVKD-QRMMWGTTRTLIANIVGMTEGLYLVGVGFRANLLHMKLGYTHSVYVPIPMKAEVPSATKISLFCTDKQLLGEFARKIKSLRMPEPYKGKGIFIGKETIRLKS Schpo1 MNFTTCSYVGKKEIIV-PKNIQFDLQITGPHGTLNMRFPNYLNLMDANIEK-QRAMWGTTRAILANVKGVTMYIKLVGIGYRTSLIHLKIGYANDILVSIPVQVENPTPTSLVLRGIDRQKVTQFAAKIRSFKKPEPYKGKGIYVDGEKPQLKA Sorma RNFSATSKLGRTPLSI-PPGVEITITVQGPLGQLEMDIPDFIKIATLSVAN-QREMWGTTWAYLNRIMGVSEGLRLVGIGYRATIVCLKLGFSHPVEMGVPIKASTPQPTRILLEGINREQVMTFAADIRRWRVPEPYKGKGIFVNGETIKLKQ Sphar ------SRLAKRPMPI-PAGAKLTLKVIGPKGVLATRLPSNVSVLLFTCQN-NKQMHGLSYGIIGNLTGVTLGLELQGVGYRAAKLSINIGFSKPVIFEPPIKLDLLNPTNLLVRGIDLQQVGAIAAKIRAIRPPDAYKGKGIRYGDEQVRLKA Spipu1 RSFTTTSMIGRRVLKY-PHEVAITVTVKGPRGSLSMPLQPFVAVLSVSVTD-QRAMWGTTRALLENVEGVHEGIRFNGVGYRALFLSLKLGYSHPILLDIPVDVKIPAPTRIILQGNDLQKITQFAASIRKWRPPEPYNQKGIFIGDETIKKKE Sporo1 RSFTSTSHVGSAPIPY-PSSVTFELLVQGPKGRLAVPVPPFVKLLSLAVED-QRAAWGLTRSLVANVQGVSQGLRLVGVGYRAAVLNLKLGFAHPVLIDLPVQASTPSSTTIVLSGIDKQRLGEVAARIRRWRVPEPYNGKGIFVGSEQVKRKE Stehi1 ---------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 RSFSTASYIGSAPIPL-PKEVSLSLVVSGPKGELDLSIPHYLKLVTLSVQD-QRSMWGTTRALLHNIVGVTEGLKFVGVGYRAAIIVLRVGFSKPVVLEIPIAANCPQPTALILNGRDKQVLTQFATVIRSYRKPEPYKGKGIFVNNETIKIKS Thetr RGFAAATELEQAALYR-KMAVAVVVPLRGPLAEAALKAAMFVPQAHHAIRPRQRALFGTVKSAVASLEGLDRGLNLVGVGYRAWLLWLKLGYSHDVEVPIPLAVKVIKDTTIVVEGIHKQQVGEFAAQLRRHRKPDAYKGKGVRYDGEVLTLKQ Treme1 ------------------------ITVTGPLGEQVVPILPPIILLSLTIHN-HRSLWGLTRSLIHNVQGVTTGLRLVGVGYRASVLNIKLGYAHPVLIDIPIEVETPQPTKIILRGTDKQKLGRFAAKIRRWRKPEPYRGKGIFVGDETIKLKE Trire2 RPFSTTSKLGRTPLSV-PPGVEVVITVTGPLGTLTLDVPEFVDLATLSVRD-QKEMWGTSWSYLNNITGVSEGLRLVGVGYRASVLCLKLGFTHPVEVGIPVTVTTPSLTRILIEGPDREALMSFAGVVRKWRPPEPYKGKGVFINDETIKLKQ Umbra1 KNFTSTSHIGRKVLTF-PKEVSVELHVSGPLGKHSLPIKPFVNLVSVSVAD-QRSMWGTTRALINNIVGVTEGIRLVGVGYRATLLSLKLGYSHPVEMALPVTCTIPQPNRLILQGSDLQQVKELAAKIQRWRKPEPYNQKGIFIADETIKKKE Ustma22 RIASTPSHVGSAPLDL-PASTTIEVLVKGPLGEVVVPLHDCVVLISLSIKD-QRGLWGLTRSLLFNLHGVSEGLKLVGVGYRASILHLRLGYSHPVLLPVPIQAQTPQPNRIVLKGADKEQLGLFASQIRSWRKPEPYKGKGIFVNDETIRLKT Walse1 RYFSTTSHVGKNPVNI-PASIQVSLSVKGPLGEEYVNLQPFIQLIRVSVLD-QRSMWGLTRTLIQNITGVTEGVRLVGVGYRAAIIHLKLGFSHPVVMQIPVTAETPAPNRIILHGSNKHQVTAFAAAIRHWRKPEPYNGKGIFINDETIRRKD Zygro1 RCFSVSSHIGSSPIYL-AAETKFSVTVEGPKGQVAMEMPDFVKVLNVSVLD-QRSMWGTMRSHINNVTGVSEGLKFVGTGYRAQVVSVKVGASVMQGLTVPIKVTSPVPTSLIIEGCDKQQVHLFAAKLRNFHPPEPYKGKGIYVNNETIKLKD [Cluster2964.fasta_al_trimmed; alignment length = 99] Allma1 --------------------------------------------------------------------------------------------------- Ashgo11 DPKLLQQLPDEPALMRAFDNFEMLIENLDNANNIENMRLWAPLISILQLRECALSVVGTAVQNN-EKSQSNFLKIIELAVRTKAFYALSNIVRHASALF Aspfu1 NPEMLSALPSDADLMKAFDNFEQLIESIDNANNLEPLGLWTPLVELLEMRRMAAWCIGTAVQNN-EKAQDKLITLVAMSARKKAVYAISSGVRNAMDEF Aurde31 DPGIIDHIKPDAVQMKALDHLEMLIESIDNANDMTKLNMWTPLLSLLPIVVNTLWVLGTAVQNN-PRAQADFLLLLSSIVRAKALYCLAGLLKFAVSRL Batde5 DSKWIDLIKGDAVRMKACDELELLVESLDNANDLKSLKLWQPIISLLQLRMYGAWVLGTAVQNN-PKSQKDFMPILNLLVRTKAFYCISGAIKHVFEAF Botbo1 DPAIIDHIKPDAVLMKSLDDLEMLIENLDNANDLQTLKMWEPIISLVAIRLNALWVLGTAIQNN-PKAQSAFMTILSVITRSKAIYCLSGALKHAVDKM Botci1 PADAMNVLPSDADLMKAFDNFEQLIENLDNANNIEVLELWKPLLEFLEIRKMAAWCVGTAVQNN-EKSQKSMLLLVKMCVRRKAVYALSSAIRNGMDVA Caeel --------------------------------------------------------------------------------------------------- Canalb1 DQKALNQLPDEATLMKALENFEMLIENLDNANNIGNLKLWNPLIDILELKVLICGIIGTAVQNN-PKSQEDFNELIELALQSKALFAISSFIRNGYAKF Cangl DPKLLEQLPDDPTLMKAYDNFEMLIENLDNANNIENMKLWEPILKTLDLRASGLSVIGTAVQNN-TDSQTNFLILIAIAVRIKAFYALSNLLRNAGKKF Capow DRKWMEAVKDDVTRMKALDDLLFLVESIDNACDLHTINALVPVANLLTLRSGAAWVIATAAQNT-PKVQKQMLRLTQLLIRAKALTAVSAILGHGVERF Catan2 --------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------- CocheC53 DVEALQRLPSDAQLMQAFDNFEQLIENLDNANNIESLGLWMPLVQQLELRFYAAWCCGTAVQNN-IRTQERLLTLVRMAVRKKAIFALSSSVRNGLDAA Coere1 DPAVLDVIKPASVQMTALDDLEMLVENIDNANNLEPLGMWPRLIKLFSIRVGALWVSGTAVQNN-PKAQAKFSSALRVLVRTKALYCVSSCVRGGLTEF Conco1 DTSIIDHIKDESTQMVAFDNLEMLVEHIDNAKNLEPLKLWEPILALLVLRKYAAWVCATATQNN-PQAQKNFLSIIDCLVRKKCIYAISCSIRHALTQF Conpu1 DPAIIDHIKPDAQLMRALEDFQMLVENIDNANDLKKMNMWQPIQDLLDIKTNTLWIIGIAIQNN-PSAQSAYLQLLPFLARSKAVFTLSSLLKHAIQQF Copci NPEIIDMIKSDAELMKALDHLEMLIEQIDNANNLEKLKLWEPLQSILEIKVATLWVIGTAVQNN-PAAQDVYRTILSFLERSKAIYTLSGLLKHALKDL Croqu1 DTGVLDAIRTDAIRMKAGEELEELVQDLDNANDLEVLGIWPKLIKLLTIKFHTCWICGTAVQNN-PRSQLSFLILLDILTQAKALYCLSSSLKHALESF CryneH991 TTEMLDLIKGDSITMKALDDFEMLIELIDNANNMPILKLWDPLLTLLEIVAHTCWVIGTAIQNN-IKAQAAFYRILEIIVRAKATYALSAALKHALCTA Crypa2 TPEVLASLPSDAELMVAFDNFEQLIESLDNANNMVTLKLWPPLLSMLELRRYAAWCIGTAVQNN-EKSQAGLLGLVDMAVRRKAIYALSSACRNAMDIV Debha1 DPKMLEQLPDEPALMKAFDNFEMLIENMDNANNIENIKLWQSVIDKMSLRVYAASCAGIAVQNN-PKSQEDFLLLISICLRLKALFAISSLIRNGYAKF Dekbr2 DPKALAQLKDDPTLMKALKSMEALIENLDNANNLKNMKLWPSILEQLEIQALACSCIGSAVQNN-PRSQNDFLKILKLASRSKALYALSNITRHAYEQF Dicdi --------------------------------------------------------------------------------------------------- Dmel DPERAQFLVDAAAALKSLDVIRSHIDDIDNAITLVKLGGTATLLRYIEVRESALNTVAEVAQNN-VFCQNALIALAKNLVRC-SLYAISSLIRNGYDEF Enthi --------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------- Fomme1 DPGIIDAIRPDSVLMKALDDFEMLIEQIDNANNIEKMSMWPTLRDLLAIRAAVLWIIGTAVQNN-PSAQNAYLVILSRLTRSKAVYALSGLLKHGVKLM Fusgr1 TPELMAALPSDADLMKAFDNFEQLIENLDNANNIANLSLWTPLLDQLEMRKMAAWCVGTAVQNN-EKTQERLLMLVDLAVRRKAVYALSSAVRNAMDLF Galma1 DPAIIDLIKPDAEQMKALDHLEMLIEHIDNANDLEKLKLWEPLQSLVDIKTQGLWVIGTAVQNN-PSAQDSFMTLLSFLIRAKAIYALSGLLKHAVEAL Ganpr1 --------------------------------------------------------------------------------------------------- Gloin1 DPEIINAIKSDATRIRAFDNLELLVEQIDNAIDIENMGLWPKILSFISLRKHAVWVCGTAIQNN-IRAQKAFALILDLLIKSKALYAISGAIKHGLEQF Hisca1 SPTALHRLPSDAELMKAFDNFEQLVENLDNANNLGVLGLWEPLVQELGRRMMGAWCIGTAVQNN-AGAQEMLLTLFALSVRRKAVYALSSAIRNAMDVL Klula1 DPKLLEQLPDEPTLMKAFDNFEMLIENLDNANNIENMKLWEPLITVLELRAFALSVTGTAVQNN-DQSQNNFAKVIKLAVRTKAFYTLSNLIRHIYDQF Lacbi2 NPEIIDMIKPDAELMKALDHLEMLIEQIDNANNLEKLRLWEPLQSILEIRMQVLWVIGTSVQNN-PAAQDVYLTLVSFLIRSKVIYALSGLLKHAVVEL Lenti61 DSGIIDAIKSDAELMKALDDFEMLIEQIDNANNLEKLKMREPLHALLAIQMATLWILGTAVQNN-PSAQNSYLALLSFLTRAKAVYALSGLLKHAVSQL Malgl1 DPGLYDAIKSEAQMMQALDNFEMLVEQVDNANNMEPLGMWPPVLSLL---------------------------------------------------- Mellp23 DTSILDTIRTDAIRIKAGEGLEELVQDLDNANDLEVLGVWPKLIKLLQIQFYTCWIIGTSVQNN-PKSQLAFLLILNVLTKAKSLYCLSSTLKHALSSF Mnele DQERREFLEDPVKSMRALEEIAFHAEDIDEANDLYLMGGLQVCCAYIELQSLACEVIASAVQNNEKIVQFA--DLLKLVVRVKSLLAVSCLVRGALAKF Monbr --------------------------------------------------------------------------------------------------- Morel2 DPGLIDAIKSESQMMLAWEDFEMLIQQIDNASNIENMKMWPPILEELKYREQAAWVCGTATQNN-PKAQAAFLPVIGLLVRAKAVYALSGAIKHALNEF Mucci2 DPKVLEAIKDDATRMKALDNLELLIEGIDNARNIENMKLWPAIIKQLEVRKGTAWVCGTAVQNN-PEAQKAFMPLVKLLVRSKAQYAISGFLKHGVEAF Mydma --------------------------------------------------------------------------------------------------- Neucr2 DPEVLASLPSEAELMKAFDNFEQLIENLDNANLLEELSLWSPLISLLDMRYHAAWCLGTAVQNN-QKTQERLLKLVDLAVRRKATYALSSAVRNAMDVA Orpsp11 DPKWLDVIKDDSVRMRALDELEMLVEQIDNANNLRPLKLWPVLLDVFEIKMYIAWIFGTSVQNN-ETAQKDFIPVLNALVLKKIIYCLSGFLKHGLKTF Pench1 TPQMINTLPSEADLMRAFDNFEQLIEGIDNANNLVPLNLWKPLVELLEIRRMAAWCVGTAVQNN-PQAQDQLVTLVTLATRKKAVYAISSAVRNALDAL Phybl2 DPAIIEAIKDDATRMKALDNLELLIEGIDNAMNIENMKLWPSIIAQFSLRKGAIWVAGTAVQNN-PAAQKALLPLVAILVRSKAIYAISCFLKHGVEGF Picst3 DPKMLEQLPDEPTLMKAFDNFEMLIENLDNANNIENMKLWPAIVNQLTLRVYAASVIGTAVQNN-PKAQEDFNKLIKIALLLKTLYALSSAMRNAYANF Plicr1 DPAIIDHIKPDAVLMQALDDFEMLIENIDNANNVEKLKMWEPLHDLLAIKMQTLWVIGTCLQNN-PAAQSSFLTLLSFLTRSKAVYALSGLLKHAVTKM Polpo --------------------------------------------------------------------------------------------------- Pucgr2 DTGVLDAIRTDAVRMRAGEELEDLIQDLDNANDMEVLGFWPKLITLLLIKFHTCWICGTAVQNN-PKSQIAFLTILEILTQAKAMYCLSSTLKHVMKKF Punst1 DPEIIDMIKPDSELMKALDDFEMLIEQIDNANNLEKLHMWEPLHNLLSLKSHVLWILGTAVQNN-PAAQHAYSTLLSFLVRSRAVYALSGLLKHAVRQL Rhior3 ------------------------------------MKLWPAIIKQLEVRKGVAWVCGTAVQNN-PKAQTAFMPLLNLLVRNKALYAISGFLKHGVLEF Rhoto1 NTDILKAMQSDADRMKAWEDLEMLVEELDNANDLQNMGLWQPIVKHLEVVKHACWVCGTAVQNN-PKSQQAFLTVQSILTRAKAMYCLSSTLKHAVQRF Rozal11 DPSMVDEIPSDSDKMIAFDNFEMLIENLDNANLMQKMALWAPVISMLEMRMYAAWVIGTSVQNN-STAQSDFIKIVQMVVLKKIVYALSSLLKNGVKQF Sacce1 DPKLLQQLPDDPTLMKAFDNFEMLIENLDNANNIENLKLWEPLLDVLELRAAALSIIGTAVQNN-LDSQNNFMSLIEIAVRTKAFYALSNLIRNISEKF Salro --------------------------------------------------------------------------------------------------- Schco3 DPGIIDHIRPDSELMKALDHLEMLIEQIDNANNLEKLNLWEPLHSLVPVALQALWVVGTALQNN-PSAQDSYIALLGFLLRSKVIYTLSGLIKHVVSTL Schpo1 DPSVLDHIANPADEMRAFDNLEMLVEHIDNANNLVPLQLWPRLLKQLTLRRLAAWTIATAVQNN-PKSQQALIILFGALTKNKVLYAITSELKLGIALL Sorma DPEVLASLPSEAELMKAFDNFEQLIENLDNANLIEKLSLWSPLLSVLEMRFFAAWCVGTAVQNN-EKTQERLLKLVQLAVRRKATYALSSAVRNAMDVA Sphar ----LNTIFGDMSLTKALKDLSQLVDSIDNALALISMGGYPYVIALVSLVQRALDVLAITTQNN-PDCQNYCLIVLPLLVQTKALYFMSSLIRHATAEF Spipu1 DPKWIDVIKDDAVKMKAFDELEMLVESLDNANDLRPLSLWTPIIDQLKMRMYAAWVLGTAVQNN-PRSQTDFLPILRVLVRAKALYCVSGAIRHLFDAF Sporo1 --------------------------------------------------------------------------------------------------- Stehi1 DPGIIDAIRPDSELMKALDDLEMLVENIDNANDLERLKMWEPLHGLLAVKTQTLWVIGTAVQNN-PKAQEAYLTILVFVLRSKAVYCLSGLLKHAVDQL Tapde11 DAAMLDELPDDAHLMLAFENLEALVEQIDNAKNLQNLRLWQPVIAQLTCRVGGCAVIATALQNN-PVSQADFLGLLRLFVRRKALFGITAALRNAQTRF Thetr DPKWLDAMPDEAKKMKALEDLLFMVENIDAASDLCRIDGVAPLLMLVSLRIGAAWVLATASQNN-PFTQEIILDLASVLLAKKLLSLVSALIEHLLAAA Treme1 TPRY-DLI----LTI-ALDDLEMLVESIDNANNLAVLKLWEPLLSLLEILAATCWIIGTAVQNN-IKAQAALHPILSLLTRARATYALSSSLKHAL--- Trire2 TPEIMEALPSDAELMKAFDNFEQLIENLDNANNIANLDLWTPLLDQLEMRKMAAWCVGTAVQNN-ARTQERLLSLVEMAVRRKAIYALSSAVRNSMDAC Umbra1 DPKVIEAIKDDATRMKALDNLEMLIEGIDNAMNLENMKLWPAIIAQLEIRKGVAWVCGTAVQNN-PKAQQALLPLLNLLVRAKAQYAVSGLIKHGLAQF Ustma22 DPNLYNAIKSEAQMMAALDNFEMLIEQIDNANNMTSMKMWSPIISLLEIQTAAAWIIGTAVQNN-DKAQMAVLALLDLLVRAKAMYALSGLLKHAMHQF Walse1 DPAVLDKIKSDAEMMKALDNFEMLVEQVDNAKNMKKIGLWDPIYTLLDIKIAAAACTGSAINND-YDTQDTFMLFISYLLQNKAVLNISGLLKHAIHRF Zygro1 DPKLLEQLPDEPTLMKAFDNFEMLIENMDNANNIENLKLWNPLLQQLDLRTYALSCVGTASQNN-VKTQDDFLKVIELAVRTKALYALSNLIRNSSEAF [Cluster2966.fasta_al_trimmed; alignment length = 81] Allma1 AVVGKNNPLLILKYHYLAHMSCDYVDEKDLYLGLLCTIES-QNVYGYMTNTRVKFLIVITKDSEVKAAFDVIHSAYLGNPF Ashgo11 --------------------------------------------------------------------------------- Aspfu1 CVIGKDNPLHIVNFSFYLNACLDIFEIRGQDLGLLHAIDERLAAYGWLTTTGVKFLIVVLRESDLKPAFSLQRSRG----- Aurde31 AFVSANFPILVLKYHYLAHTALDVVEERDCYLGLLYAMED-VAIYGYMTPLKLKIILALVRDADVVLIFKAFHTAYISNPF Batde5 AVIGKNNPLYILKYHFLAHTSCDVLEEK----GLLYIMED-LSVYGYMTNTRIKFVLMVIKDQDIKGIFRKIHSAYQLDPF Botbo1 AFITPNAPILVLQCHYIAHMSLDVIEERDCYLGHLYSMED-VAVYGYITATRVKIVIALVKDGDIIAIFKALHTAYLANPF Botci1 GVIGKNNPLHILQYSLLLSSTLDIFDSRTGDLGLLYAVDERLAAYGFETNTGVRFVVFVVREGDIRSIFKAMQAAYLQNPF Caeel GVVGFVNPRYALEIEMFTFCSLDIVDEKEMFLGQLYNDQK-WRSFGYITNTGVRMILVLLKDQEIRLIFKRFHGHYISNPF Canalb1 --------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------- Capow AIVGKNEPLFLLKYHYIVHTALDVVEEKELYLGLLYPAEE-YKVYGYVTNTRVKLIAVWLREMDVRSFFRRLHDIYLCNPF Catan2 AIVGKNNPLLVLKFQFLSHAACDYADAATGYLGLLTTLDD-LTVYGHQTNTKVKFFLFVTKDVEVKAAFELIHQAYLANPF Cioin AVIAKNYPLYILKFHFTVHTSLDVVEEKEFYLGQLYPSED-YRIYGYVTNTKVKFVMVVIRDNDVRSMFRRLHNAYVCNPF CocheC53 GVVGKNNPLHILEFQFLLSSCLDIFEARDQDFGLLQAVDERLAMYGWLTNTGIKFIIVVLRDADMKPAFRALQTAYLRNPF Coere1 AILNRGNPLYLVKFHYLVYTSCDVIEERDLFLGLLQTIGD-MAVYGYMTNTGKKIILVTIRSARIKEICQSVHAAYVCNPF Conco1 GIIGKNEPLFILKFHYLIHTSIDLIEEKEQYLGLLHIVED-FVIYGYVTNTKIKLILIAIRDIEVKKIFKNILASYISNPF Conpu1 --------------------------------------------------------------------------------- Copci AFISPNHPILIIKYHYIAHTSLDIIEERDCYLGLLYSMED-VAVYGYVTPLKVKIILAIVKDSEVISIFKALHMAYISNPF Croqu1 TIIGRGQPLYMLKWYYAAHTSLDVFEERDTYFGLLYTMED-YACYGYQTNTKVRFVVCLVKDTEVKALFRSLHSAYLSNPF CryneH991 CILSPNTPLYVLRHYHLNHAAVDVLEERDSYLGLLYSLED-MAFYGFQTTTKLRIVLSVIKDADIVAIFRAVHNLVCNNPF Crypa2 GVIGRNNPLHILQFSLLLSSTLDIFELRSGDYGLLHAVDERLAAYGFETNTGVKFVAVVLRESDLKVVFKAMQSAYLQNPF Debha1 --------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------- Dicdi AIVGKNNPLFILKLHYIVHCSLDIIEDKDMYLGLLYPTED-YKVYGYLTNTKIKFIIVVIKDSDLKLFFKRLQTLFTSNPF Dmel AVIGKNAPLYLLELQYHVNAALDVVEEKELYLGLLYSTEN-HKIYGFVTNTRVKFIVVILRENEVRAIFRNLHLLYICNPF Enthi --------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------- Fomme1 AFVSPNHPILILKYQYIAHTSLDVIEERECYLGLLYTLQD-VAVYGYVTPLKVKIILSLVRDADITMIFRAMHMAYLANPF Fusgr1 GVIGRNNPLHILQFSLLLSSTIDVFDLRSGDFGLLHAVDDRLAAYGFETNTGVRMVCVVLRDAELKPVFRAMQHAYLQNPF Galma1 AFVSPNQPILIIKYHYIAHTSLDVIEERDCYLGLLFSLED-VAVYGYITPLKVKIVIALVRDTEISTIFKALHMAYISNPF Ganpr1 AYIGKNNPIFVLRYHFISHVSCDIIEERDLYLGHLSSMED-IAVYGCVTNTKIKIVVILVKDSDMRQLFKRLHSAYVSNPF Gloin1 AIIGKNNPLYILKYHYIAHTSCDVIEERDTYLGLLYAMED-LDVYGYITNTRVKFVVVLIKNTDMKNLFKRIHNAYVCNPF Hisca1 --------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------- Lacbi2 AFISPNHPILIIKYHYIAHTSLDVIEERECYLGLLYSMED-VVVYGYVTPLKVKIVLAFVRDIEVTMIFKALHMAYTSNPF Lenti61 AFVSPNHPILILKYHYIAHTSLDVIDERDCYMNLLYTMED-VAVYGYITPLKVKIIIALVRDADVLTIFRALHTAYVANPF Malgl1 AIIGPNVPLYLTKWHFLAHSALDMVEE-NPYLGLLLTIED-SAIYGYQTNTNTKFLLMFFPDEDIKTLCKAIHAVYVSNPF Mellp23 AIIGRGQPLYMLKWYYAAHTSLDVFEERDAYFGLLYTMED-YACYGYQTNTRIRFVVCLMKETEVKAIFRSLHSAYLSNPF Mnele -------------MHFLVHTSIDVIEEKDLYLGQLYPNED-YRIFGYVTNTKIKFV-VLIKDGDIRQLFSKIHSAYVCNPF Monbr --------------------------------------------------------------------------------- Morel2 AIIGKNNPLFILKYHYIAHTSCDIMEERDMYLGVLFSMED-LSVYGYMTNTKIKFITVLIKDTDMKNIFRRIHAAYASNPF Mucci2 ALIGKNNPLFILKYHYIAHTSIDVIEERDLYLGLLYAMED-LAVYGYITNTRVKLVVVVIRDADMKALFRKIHAAYVCNPF Mydma AVVGKNEPLYVLKFHYIIHTCLDVIEEKELYLGLLYPTED-YKVYGYVTNTKIKFVIVVLRDNDIRMMFRKVHSAYVSNPF Neucr2 GVIGRNNPLHILQFHLLLSSTLDVFDLRSGDFGLLHAVDDRLAAYGFETNTGTKFVAVVLREGEMKVVFKAMQTAYLQNPF Orpsp11 AIIGKNNPMFILKFHYLANISCDLIEAKDSYLGLLYIMED-LAVYGYLTNTKIKIIIILVKDMEMKQIFRKVHGVYISNPF Pench1 CLHWRDNPLHIIEFSFLLNSCLDIFDIRDQDLGLLHAIDERLAAYGWLTTTGVKLLIIVLRDSDVKPAFRALQSAYLQNPF Phybl2 ALIGKNNPLYILKYHYIAHTSIDVIEERDLYIGLLYAMED-LAVYGYITNTRVKCVVVVIRDADMKLIFQKVHAAYVCNPF Picst3 --------------------------------------------------------------------------------- Plicr1 AFISPNQPILILKYHYIAHTSLDVIEERECYLGLLYAMED-VAVYGYITPLKMKIVVALVRDVEIQQIFKALHMAYVSNPF Polpo AVVGKNDPLYFLKLHYIVHCSLDIIEDKDMYLGLLYPTED-YKVYGFLTNTKIKFIIVVIKDSDIKVLHLR----YASNPF Pucgr2 AIIGKGQPLYVLKWHYAAHVSLDVFDERDCYFGLLYAMED-YACYGYQSNTRIRFVLCLIKDTEVKLLFKSLHAAYICNPF Punst1 TFVSANHPILILKYHYLAHTSLDIIEERDSYLGLLYSMDD-VAVYGYMTSLKVKIILALVRDGDLLQTFRALHLAYVANPF Rhior3 --------------------------------------------------------------------------------- Rhoto1 AVLGRGNPLFLLKWHYAANTALDFFEERESYLGMLFAMED-YAVYGYQTNTRIKFVLAIVRDLDVKTIFRAIHNAYISNPF Rozal11 --------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------- Salro AIVGRNEPLLLEPIEHIIYAALDVVDDHKFYLGALYPLED-GKCYGYLVNTKIKFFIITHSDQDVQSIFQQLHSEYACSPF Schco3 AYISPNQPILIVKYHYIAHTSLDVIEERECYLGLLYAMED-VAVYGYVTPLRVKIVVAFVRDIEVNTIFKALHMAYISNPF Schpo1 SIAGPDEQLYLARYQYLGELSLDVINDLDCFLGLLGVEED-ISTYAFYSNTKVKFILAVVKETEIRQLLRRIYTIHVCNPF Sorma GVIGRNNPLHILQFHLLLSSTLDVFDLRSGDFGLLHAVDDRLAAYGFETNTGTKFVAVVLREGEMKVVFKAMQTAYLQNPF Sphar --------------------------------------------------------------------------------- Spipu1 AIIGKNNPLYILKYHYIAHTSIDIIEERDQYLGLLYAMED-LAVFGYITNTRIKFILVIIKDQDMKNLFRRIHNAYVSNPF Sporo1 AVLGKGNPLFLLKWHYAAHTALDFFDERESYLGLLYAMED-YAVYGYQTNTRIKFVVILIRDVDVKTIFRAIHNSYISNPF Stehi1 AYVSPNHPILILKYHYLAHTSLDVIEERDSYLGFLYAMEE-VAVYGYITPLKVKIILALVRDLDVIAIFKALHLAYVSNPF Tapde11 GVIGRDKPLYLARLIELAFAACDIFHERDSYFGRLIALEG-ILLFGSMSNTQIRFVIALINEGKVRHVLSRIQAEYVMNPF Thetr -----------MGFHALMHTCLDMVEE-DSYLGLLTATED-YRVYGYVTNTRITLLAAILKASNVGSLLRYLHTLYVCNPF Treme1 AIISPNAPLYVLRHYHLAHAAVDVIEERESYVGLLFCMED-MAFYGFQTSTKLRLVISVIKDADIVAIFRAVLHLLSHNPF Trire2 GVIGRNNPLHILQFSLLLSSTIDVFDLRSGDYGLLHAIDDRLAAYGFETNTGVRMVCIVLRDAELKPVFRAMQSAYLQNPF Umbra1 AVIGKNNPLYILKYHYIAHTAIDVIEERDAYLGLLYAMED-LAVYGFMTNTRVKIILVIVKDADIKAIFTKVHSAYVCNPF Ustma22 AIVSPSGPIYVLRYHYFAHAALDVMDEREQYLGLLYTIED-LAIYGFQTCTQLRFLIMLVRDIDMLTLFRAIYTSYSANPF Walse1 --------------------------------------------------------------------------------- Zygro1 --------------------------------------------------------------------------------- [Cluster2969.fasta_al_trimmed; alignment length = 123] Allma1 --------------------------------------------------------------------------------------------------------------------------- Ashgo11 LVFDLD-DVRRIR-GLGVLGTLCGSLPAQQNLFLTVPLRLMLEDAVWLVLSGLIYRYLR-EE--QYFLSAGGRFGARYVAYPGDPLRYHSHMAVQPLHVVGGGRLGTGVKKLWVVFSIEWSGF Aspfu1 YLFSID-AVTYLRREHHICGVLIGTLPPQQNVFLGLPLELMPEEARLLVEKGPLFAHLH-AE--GYYLSPGLRFGCQYLAYPGDPLRFHSHFLV-VMDIIVGGRLGTGVKKGFLLFSIEWAGM Aurde31 LVFSVE-DIAAIRTEHRICGLLIGTLPAQQNMFLGPPLVLTPEEVVQLVTNEAVFQALW-AK--GYWMGGGLRFGGDYLVYPGDPLRYHSHFVATVMEIVAHGRLGTGTRKSHLFYSIEWSGF Batde5 LVWDAK-DAQILRRKWRIIGGFVGSLVPLQNTLHGLPLLLSPEQVHFLISNGTVFLFLW-RA--GWFISSGSKFGGDFLLYPRDPSLCHAMYIVKIADIVRAGRLATFSKKIFMYIPISWVK- Botbo1 YVWSPQ-DLHTLRADHHITASLIGTLPAQQNVFLGLPLSLMPEEVVYLLEKGAVFRDLI-TK--GYFLGGGMKFGGDWLVYPGDPLRYHSHFVATVMDIVAFGRLGTATKKAHLLYSIEWASF Botci1 LLFDID-VVTHLRRTYHICGVLTGTIPPQQNLFLGLPVELLPEEAKVLVDKKPLFAHLH-SR--DYFMTPGLRFGCDYTVYPGDPLRFHSHFVA-TLDIVGGGRLGTGVKKGFLIFCIEWGGM Caeel --------------------------------------------------------------------------------------------------------------------------- Canalb1 LVFNVD-DIKTLRNEYNILGVLMGTLQPQQNIFLSVPLKLIIWEVIWLLQYNKYYSYLQ-NK--GYFINPGIKFGGDLVIYPGDPLRYHSYSIV--HDVVVGGRLATSVKKNLVLFSIEWAGF Cangl LVFDLE-SIRYLR-ELGIAGVLSGTLPTQQNLFLTVPLRLMIEEVLWLLIN-LLYQQLR-NQ--NYVLAPGARFGGKYIAYPGDPLRYHSHLTIQDLQLLSGARLGTTVKKLWVFYSVEWAGF Capow IVYDKH-DVYRLRREFRIVGALLGEIAVSESTQLGVPLVLMPEQTTVLLQHGRVFSELW-QR--GHYMTAASKFGGDFLVYPGDPFRYHSQFVAIVVDLAAIGRLGTTVRKTVLLVSVNWSGM Catan2 --------------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------- CocheC53 LLFDVD-VIAHCRRAHNICGLLVGTIPSQQNVFLGVPLELMPEEARVLVDKGPLFRYLH-SK--GYYHMPGLRFGCHYNVYPGDPLRYHSHFAA-TLDVVGGGRLGTGTKKAYMIFSVEWAAL Coere1 ----------------------------------------------MLAETGALYKDLH-RQ--GYYVDRGIKYGGDYLLYPGDPLRHHSSHVVTLRELVPLGRVGTAVKKARLLITMNWSAM Conco1 --------------------------------------------------------------------------------------------------------------------------- Conpu1 YVWDVD-DIAVLRSHHHICGALTGTLPSQQNVFLGVPLVLMPEEVVLLLEKKGVFRSLW-EQ--GFFMGVGVKFGGEYLVYPGDPLRYHSHFVASVMEIVAHGRLGTGTKKAHLMTSIEWAGF Copci YVWDVD-DIATIRSKYRLCGVLSGTLPSQQNVFLGIPLVLLPEEAVLLVETGGVFKGLW-DQ--GYFMGGGIKFGGDYLVYPGHPLEY--------VQ------------------------- Croqu1 FIWNIN-DLAQLRVDHHICGLLTGTLPAQQNVFLGLPLQLLPEEVVLLVELGEVFKALW-KQ--GMYMGIGFKFGCDFLVYPGDTLRFHSHFACTVIDLVSFGRLATAVKKAHLLLSLEWAGM CryneH991 TVWDAQ-TAATLHCVHNVSGLRAGTLPAQQNGFLGLPLTLMQEEAAYLVTQGGVFSKLQ-SL--SYRVGLGPRFGGEWLIYPGDYLRYHAHFTSQVTEIVAWGRLGTGTKKAGLIYSLEWANF Crypa2 LVFEVK-DVATLRREHCICAVFVGTTPPNQNVFSGLPIELLAEEAKLLVDKGPLYKHLN-AG--GYYITPGIRFGADYSVYPGDPFRYHAHFMA-TLDLVTGGRLGTGVKKGFLIFTIEWAAM Debha1 LIFDIE-DIKKLR-NLGILGILSGTLPPQQNIFLGIPLQLSVNEALWLIEREHTFKTVR-DK--GFFILPGLRFGGELIAYPGDPLRYHSHLIINTLDVITGGRLATGVKKVWLIFSIEWAGF Dekbr2 MLFNLN-HIKHLRVHHGIIGLLSGSLPPQQNTLLGLPLTLSIYEVLYLLFNGRVFNYMKLNF--HHTLLPGVRFGGKFVSYPGDPLRYHSHLIV-DLDITNRGRLATGVKKLWLIFSIEWSGF Dicdi --------------------------------------------------------------------------------------------------------------------------- Dmel FVFNVD-DYMELRSKHRIMGAPVGTANPNQSTL---PVELSKFETQLLLDENRVFKDLW-RR--GKYVTSGDAFGADFLVYPGDPMIYHASHIVILLELIAKVRLSVIVNKSCVFQTVAWCNL Enthi --------------------------------------------------------------------------------------------------------------------------- Falba LIPSIA-DIIWLRQEHRIVSQLAGTLAPSQSSSLSTPGVLSRTQGRFLFAQGLVFRHLALTCGLTLTASGSTRFGGDFLAYTADPLSVHAEYIVLIEKLIAAGRLANSTKKAVLLVTLRWSKF Fomme1 --------------------------------------------------------------------------------------------------------------------------- Fusgr1 LVFDSE-AAGFLRRNENINGVLVGTAPPTQNIFLGLPIELRPEEAESLLRKNPLCGFLL-TS--GYYMTPGLRFGAKYSVYPGDPLRFHAHFMA-NLDIVAGGRLATAVKKAYLIFSIEWAAM Galma1 YVWDVD-DIATIRSKHRICGVLTGTLPSQQNVFLGVPLVLMPEEVALLVDIGGVFKDLW-KQ--GYFMGGGIKFGGEYLVYPGDPLRYHSHFAATVMEIVAHGRLGTATKKAHLLLSIEWAGF Ganpr1 LVWSVE-AITHLHT-HHILGSLTGALSPHQTLYTGVPLLLAREEVVCCVAKGVVFRDLH-GQ--GYYMTPGDRFGGEWLVYYGSPVAFHSHYITTIMDLAASCRVGTAVKKMRLLWSVEWTGW Gloin1 -------EIRFLRENYRIVGSFIGCLPPLQNQLFGLPMTLLNEEVTLLLSKGKIYSDLW-NK--GYYITSGIKFGGDYLLYPGDPLKYHSHFIATVMDIITFGRLGTTVKKSYMLFCLEWSGY Hisca1 FLFSVD-TVTYLRREHHICGVLIGTLPPQQNVFLGLPLELMPEEARLLVVKGPLFAHLH-AK--GYFLSPGLRFGCQYLAYPGDPLRFHSHFLV-VMNLVAGGRLGTGVKKGFLIFSFEWAGM Klula1 VLYDVD-DIAKIR-EHGVAGVLIGTLGPQQNVFLGVPLRLMMEEALWLVEVGKVYKKLR-EM--GYFMSPGARFGGRYVAYPGDPLRYHSHLTVQDLNMINGARLGTSVKKTWVLYSVEWAGF Lacbi2 YVWDVD-DIATIRAQYRLCGVLTGTLPSQQNAFLGVPLVLMPEEVALLLEIDGVFSGLW-KQ--GFFMGGGIKFGGDYLVYPGDPLRYHSHFAASVMEIVAHGRLGTATKKAHLLLSIEWAGF Lenti61 YVWDVE-DIATLRAKHHVCGVLTGTLPSQQNVFLGVPHVLLPEEVVLLLEKQRVFQDLW-EK--GNYMGGGIKFGGDFLVYPGDPLRYHSHFVASVMEIVAHGRLGTATKKSHLFFSVEWAGF Malgl1 FLWDVS-DVDRARTQHHICGLLTGTLPPQQNVFLGLPLRLIPEEVVYLLRKGAVFEDLH-EK--GFFLSTGLRFGGDFVVYPGDPLRYHSHFTATIYHIISSGRLGTAVKKSHLLWSLAWAGF Mellp23 YIWNID-DIAQLRVDHHICGMLTGTLPAQQNVFLGLPLQLLPEEVVLLVELGEVFKALW-KE--GMYMGIGFKFGCDFLVYPGDTLRFHSHFACTVIDLVAFGRLATAVKKAHLLLSLEWAGM Mnele LVWDPD-TVEFLRKEYGIVGVCIGTLPPRQNKTLSLPLQIMKEEAVILKIGGVALQDLR-RR--NYLVTSGTKFGGDFLVYPGDPLVYHSYFVVKVNELLAFSRLASSVKKVNDFFRTEDPAY Monbr --------------------------------------------------------------------------------------------------------------------------- Morel2 LVWDIQ-DVRKLRQDHRIAGSLAGSLPTMQNIFQGLPLRLLPEEISILLHHDLVFEHLWKDQ--QFFIAPGMKFGGDYLLYRTDPLVCHASLVASVVDVANSARLVSTVQKQHLLFAVEWAGF Mucci2 FVFEAK-DVEQLRTKHRIVGALNGTLPPLQNTFYGLPLILLPEEVELLVNRGDVFDFFW-SQ--GFYITSGVKFGGQFLLYPNDPMCVHSEYIVSVLEIIGMGRTATNVKKTFVLYSIEWAGF Mydma FVWDAE-HVYELRMKHRICGALVGALSPWQTSVNSMPLMLMPEEVYLCLSEGLVFQYFW-KK--GYFLTSAAKFGGDYLVYPGDPLRYHSFFIVLVKELINYGRLAASVKKTVVLISLEWSYM Neucr2 LVFDID-DVAYIRRQHGICAVFTGTMPPTQNVFLGLPLELYAEDAKMLLDRKPLYSYLN-ER--GYFITPGLRFGGDFSVYPGDPFRYHAHYMA-NLDLVTSGRLGTAVKKSFLMFCIEWAGM Orpsp11 ----------------------------------------------------KIFCDIW-EKPEKYFITSGSKYGSDYLIYPGDPIQYHSNFIATIKYIIKYGRLGTNVKKTHLLYSIEWSSW Pench1 LLFSID-AVTYLRREHHICGVLIGTLPPQQNVFLGLPLELMPEEARLLVDKGPLFAHLH-SK--GYFLSPGLRFGCQYMAYPGDPLRFHSHFLV-VMDLVVGGRLGTGVKKGFLIFSLEWAGM Phybl2 VVYCAHPDVERLRCDHRMVGALVGTLPPLQNTFHGLPLLLMPEEVTLALSKNSVYAYLW-NL--GFYITRGTKFGGDFLTYPGDPMRFHSHCIVEAIDLIGKGRLATNVKKTFVLFTLSWAGF Picst3 LIFDVR-NIRILREKYGILGVLTGTLAPQQNFFLSVPLKLFIWEVIWLVESGHNFKYLK-EM--GFFMNPGLKFGGDLVIYPGDPLRFHSYSIV--QDLVVGGRLATSVKKNIIIFSIEWAGF Plicr1 YVWDVD-DIAALRARHNICGLLTGTLPSQQNVFLGIPLVLMPEEVVLLVEKEGVFRDLW-ER--GNFMGGGIKFGGDYLVYPGDPLRYHSHFTATVMEIVAHGRLGTATKKAHLLYSIEWAGF Polpo FVWDSS-----------------------EEVALGVPL---PEEIIKLNETR--------EK-KASIIDYGVKFGGSFLAYPGDPLLHHSELIVIVHELTTMARLAVSVNKTTLLLTLTWEGV Pucgr2 YIWAVD-QVERLRIDYQISGLLTGTLPAQQNVFLGLPLQLMPEEVVVLVELGAVFSALW-RQ--GMFLGIGLKFGCDFLVYPGDSLRFHSHFACTVLSLVSYGRLATAVKKSHLLLSLEWARD Punst1 --------------------------------------------------------------------------------------------------------------------------- Rhior3 --------------------------------------------------------------------------------------------------------------------------- Rhoto1 YLWDLN-DIQRLRVQHHVVGQLHGTLPTQQNVFLGLPLVLLPEEVVLLVRNNRVFEDLW-RK--GYYMGGGLRFGGDFLVYPGDQLRYHSHFTLTVLDIVAYGRLATAVKKAHLLASLEWAAF Rozal11 --------------------------------------------------------------------------------------------------------------------------- Sacce1 LVFDID-HIKLLR-KWGICGVLSGTLPAQQNVFLSVPLRLMLEDVLWLHLN-FLYKALR-DQ--GYVLSPGGRFGGKFIAYPGDPLRFHSHLTIQDISMISGARLGTTVKKLWVIFSIEWAGF Salro --------------------------------------------------------------------------------------------------------------------------- Schco3 FIWDVD-DIATVRSRHRICGLLTGTLPAQQNAFLGVPLVLMSQEVTLLVEKGGVFRDLW-EQ--SYFMGIGIRFGADYLVYPGDPLRYHSHFAATVMEIVAHGRLGTATKKAHLLLSIEWAGF Schpo1 LVFDVQ-AVEVFRKNYHILGTLVGTLPPQQNVFLGLPMELSKEEAFYLIEKGLMFKSLV-DT--GFYLNPGLRFGCQFVAYPGDALRYHSHYLV-NLFLIGGGRLGTAVKKTWLIFSIEWAGF Sorma LVFDID-DVAYIRRQHGICAVFTGTMPPTQNVFLGLPLELYAEDAKMLLDRKPLYSYLN-ER--GYFITPGLRFGGDFSVYPGDPFRYHAHYMA-NLDLVTSGRLGTAVKKSFLMFCIEWAGM Sphar LLWDVD-DCVYLRTQLRLLGDAVGSLPIHQNVILGVPMLISPECAFMLVNQGRIFRDLY-ER--GFYMTSGCKFGGDYLCYRGDPAVCHSTFIVRILELVGLGRLGVAVKKTSLLISLSRSPF Spipu1 --------------------------------------------------------------------------------------------------------------------------- Sporo1 --------------------------------------------------------------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------------------------------------------------------------- Tapde11 LIFEVS-ILKHLREVHHICGVLIGTLPSQQNVFLGLPLQIMIEEAAYLVRHGNLFAHLH-EK--DYFLTPGLRFGAQYVAYPGDPLRFHSHFVA-SMDVVGGGRLGTGVKKAWLIFTVEWAGM Thetr MVWDAA-SVAILK-SHGVYGDVRGAEDKHETAAVESPLHLLKEDARWAANEGLAYEDLR-RK--GYTLIDGIKFGADFSIYAGDIGSVHSCYLVRV-ELAAAARVSTFARKISVLVQLEWMTR Treme1 TVWDPQ-IAATLHCLHNISGLRTGTLPSQQNAFLGLPLILMSEETAYLISEKATFKTLQ-KK--GFRMGLGPRFGGEYLIYPGDYLRYHAHFTSQVSELVAWGRLGTGTKKAGLLYSLEWANF Trire2 LVFDPD-AVSALRRRANTNGTLVGTTPPTQNIFLGLPIELRPEEVDALVRAGALCQFML-SN--GFYMTPGLRFGARYSVYPGDPLRFHAHFMA-NLDIVGGGRLATAVKKAFLIFSIEWAGM Umbra1 LVWDLE-DLKTLRTKHRIIGAMVGSLEPLQNIFYGMPLALLPEEVSLLQKQGTVFEYLW-TK--GYYVTCGTKFGGDFLVYPGDPARYHSHYVVTVRSLVATGRLGSNVKKTQVKWSVQWAAI Ustma22 LVWTVD-SLRLLRS-YGVIGSFTGTLAAQQNVFLGLPVQLMAEEVVFLVRRAALFDHML-TN--GMWCMNGLRFGGSLAVYPGDPLRYHSHYTAQLMSLVANGRLGTSVKKTHLLFSLAWAGF Walse1 ----------------------------------------------------RVFKDLW-DR--GMFMGDGLRFGGHFLVYPGDPLRYHSHYTVTVLDIVALGRLGTTVKKVHLLISLEWAGF Zygro1 LVFNLD-DIRQLR-QHGIVGVLSGTLPSQQNVFLSVPLRLMMEELLWLLWD-KLYRKLR-QM--GFTVHPGGRFGGKYVVYPGDPLRFHSHVVISELQMVAGARLATTVKKSYVAYSFEWAGF [Cluster2975.fasta_al_trimmed; alignment length = 215] Allma1 --------------------------RSSAG---------------------------------------IILVAVVLALSPILKTLTMDISSDSIWALATLLFVGHL-LLSDY-TFPGSIGTNLAIFASVLLASRLASTMHVFSLMLLAALAFIWLRRR-LSPIMAATTITTA-VLVVAVM-LSFCTPAWL-QHLHRFKSTLHGPWDQAVVLLD Ashgo11 RRLLWLRQPYPDNFT--DP-RFLTTLQ--EI--YLDVVTFHHRLTNTLLIYVVFTLL-IALAALCASLSFMIVTFTMLTLAPVLKTLSRTTSSDSIWNLSCWLTIIYV-LSYSWT---SLVPTNILLSNVTVLASRLNTTPEVFCFLLICIELNISYERN-LRYGCIVM---FTHAIVLSVA-FIFIAPGYFIYWQYK-GHEVLATWDAKKPIFD Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 RKLLYIHQDYPDNYV--DS-SFLKLMKRNVNLNYWNVVRVSQQISVEVIFVAMFIHLLIVGSCACLYILWVLFFTMLLGLTPILKNLTKDISSDSIWFMTIMMLLANL-LFHDYGRFPDSLSINAAMFASVLLASRLSSNMSVFGLMLLAVQLFAILCRS-LRSILTVILIGFA-VALSMIL-VTFMGPYLL-VFAQRYKSEIRGPWDEA--VIN Botbo1 ERVLWKKQAYADNYI--PP-SFLSSLRRNANYTYAPLVAIIQHISAVFILLSAFVHLLVWVSILLGYTAWILVFLALLALSPVLKTLTEATSSDSIWALSAFLLGLNV-LLADYSKLTSVLSMNAGISASVVLASRLSSNLSVFALILFAVQLLAILRKY-LNLISTALLITAS-GVLILAF-IGLACPAVL-VWAQKYKNEIKGSWDPAVPQLR Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel QKILYRKQPFPDNYSGGDA-QFLKELRKNVSYDYKSAVNFLTHLDMITMYFVLFLNIILYSVFIVLYLFFFTLFIFAYAFTPVIRTLTTSISTDTIYSTSIITAIFSC-FFHDYG-----TSVSTGLSSAIFLLSRLEGDTPTLLLLVVAFTLHACLSST-IF------------LSLLHIF-ILFICPLIL-ILKQTGKCTIHGPWDEAVPLKS Canalb1 KKLLYLQQPFPDNYT--DQ-SFLSQLKRNTTYSYKNLVFIVFYISCILLVILMFIGIPTLISTLVGFFSLMVITFILLIVSPILKSLTKSTSSDSIWAISCVLCLANS-IFHDYS-YRPIVSTNISLSNAIVLASRLSTTLDVFLFVLFAIEVNILFDAK-IRWPIAFLTFNLTSYLMSVFV-MVVIMPIYF-LSLQRYKNEIQGPWDVAKPKLM Cangl ERKLWKQQDYPDNHT--DS-EFYVLLKEIQA--QRIIRSFYHLVMNTSFVYVVFCYLCIGMTAL-LYVVNMLITFTMLILSPVIKSLSRTSASDSIWTLSFWLSVSYL-YVNSSS-TPTNLSTNILLANVAVLASRLPTTTEVFCFMLLCVEINITL----VSLG--------THITVVAIA-FQLLFPKWFIYWKHRYDNALLSGWDPAKPIID Capow RKILYERQPVPDNFL--PP-TFLDTVQTNVHYRYWSTVGVLLQICGVLNVLAIFHLLAVIESGITDFGSWSLFIASLAFVLPVLFSLTDTISTDTIHAMAAVALILTV-AVHDYSSFLVCSSLNTGMFACVCLASRLSSLSHVFVLVLFATAMFAAAHAR-IEVVYTIGSCAIT-ILLLTAL-ICLVCPAWL-VFVQRYKSELHGPWDEAI---- Catan2 RKVLFLRQPYPDNYV--PP-SFLHLLRTNVGPPFTSLVRVTLQFAIITCFTGVFSALVLAICLLL-----VLFVTTLLALSPILSTLTIDVSSDSIWSLSAVCLACNL-LLNDY-KFPASIATNMAVFASVLLASRLKTTESVFSLMTLSAEMFVLLHRN-Y-IMFALSLLIAS-VVLVSAS-VTFLCPLWL-QRLYRLKNTVHGPWDQAVIM-- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 KKLLWFKQPFPDNYT--DEATFLDHLQRNPRYEFWSLMVIVQHLASVIIFCCCFIAIVVGWASVLAWVLWILIYAALLGLSPILKSLTRSTTSDSIWAISAWLLMMNV-AFFDYSQLPASISTNSAMMASAVLASRLPSTTHVFSLTLFSIEVFGIFRRQ-LRLTLTMALVTCAWGSLILTFLSMGVCSWWL-IGLQKYKNEIHGPWDPARPIIR Coere1 RKLLYIQQDYADDYV--DD-TFLMELQKNANYNYSTVAVVTQHISSIVVFIAVFINLLLWCSSVAGFISWVLFAMLLFGLSPILRTLTEDTSSDTIWAMTVIFFCVNL-AFHDYSRFPGSVSLNAAVLASVLLASQLDSNLSVFAFLLFALEWFAIYRRY-LKVATTVVLAFVA-TAMGTLF-ITLGCPLWL-IWVQRYKNEIHGPWDEARPIV- Conco1 EKVLWKSTTFSDNYV--PE-DFYQNLKAYRTETYVSLVTIILRYQIVLLYVLIFNLLLIFLSF-------LIIFYFMM----------RGYFEDSIYNLTIIALIFNS-LYHDYTQYPTTISINFGIFSSVLLSSRLHSDFQVFSFLFISIVIFHIFERY-LRFLYNLVLLTIN-SILVLIA-IQFVLPAWF----KLVRGKV------------ Conpu1 QKALWFEQDYPDNYI--PPKTFLSSLRRNPNYEYWPLVSITQHMCSVALFLTVFVRLLLWATIAFTHVFFFRVFLVLLSLTPVLRGLAAAASSDSARILAVLLFALNT-LLADYTGLASLLSLNAAIGSSTLLASRLRDDLAVFSLVFFSVQLFSRLRRQ-LQLSLTAALAISS-IASILFA-VTFLSPGLL-VWAQKYKNEIRGPWDVAIPKIN Copci SKALWKSQPYPDDYV--PPDVFLASLQRNPHYTYWPLVTITQHVSVIFIFVAVFGQLLISISVLVGYAAWIMIFLSLVSLSPVLRTLSAATSSDSIWALAAVLFLLNT-LLSDYTR--------------------------------------ALIPYP-QN---------------VLFF-ITFVAPMLL-VWAQKYKNNIRGPWDVATPKVR Croqu1 KRVLWSNQLYPDNYQ--DH-TLLHQLLSGQTESYSTLVPLSAQLSSIFIFIAVFAHLLIWLTMASGYVVWSLLIFLLLLLSPVLKTLTLSTASDSIWALTAVLLALNI-LLGDYRSFPSALSLNAAIFASVVLGSRLSSNADVFGLVLFALEWFALMRRD-MMVVLNVSLALIA-LLILVPLGSTFVLPAIY-CGLQHYKRDLRGPWDCAVPRIS CryneH991 EKVLWRSQPYPDNYV--PP-DFLSELNDILPPPFYSLLPISQHISIIAVFLAIFVALVGWGCVISGWAIWILPPLLLSLLSPVLGTLTSATTSDSIWPLAGGLGFVHL-LLVDFRSLTSSLSLTSALSASVVLASRLPSTAHVFSLILLAVLLFAVVTKS-VRFLLTLSTTILA-LSLILFL-VNFIGPAML-WYAWRWKIRRGGGWDVATVRIR Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 KKLLYLQQPYPDNYT--NE-SFLAQLKRNTTYSYWKLVLVAFHLSNLLLVILIFTGIPTLMSSIIGFIIWLIIIFIILLLSPVLKSLTKSTSSDSIWALSLILCLANT-IFHDYGQYMPIISTNISLSNAIVLASRLNSTVQVFCFILFAIQINILFDFS-IRRCLVISVSGVVYYLITQGG-IAFIMPNYF-LSLQKYKNELQGPWDIAKPILN Dekbr2 KKLLWVKQDYADNYT--DT-SFLSQLKRNSTYSYWRLFLIGMHLSVIMSVILVFYGIPTIVSTFVGFVI-LLILLHLLTLSPVLKSLTNSSASDSIWAISAWLCFLNM-LFNDYVKYKSSLSKNIALSNAIVLASRLNSNLSAFCYILFSIEVCGIFNNF-TRIQLASIVFG-VDYSMLQLL-IVVAGPFYF-LALQKYKDELQGPWDTAHPVV- Dicdi KKNLYEKQPYSDNYT--DE-TFLIGLVQNANYDFWTVVTVSQQITSVILFAIIFFHSLVAMAGVLGYIA-ILLFGTVYGLSPVLRTLTNSFSDDTIWALTFILLLAHL-FFHDYGKFSAPVSLNAAIFASVLLGSRLPSNIHVFVLISYAIETFAIFRHH-LKVGLTVILCVTC-SLLIIGT-ITFVCPLWL-IFIQKYKNEINGPWDEAS-VIS Dmel VKNLYSNREYPDNYT--DA-SFLKDLRTNLHYTFGEAIVLNNQISCITGFLILYQLMILVP--ITGIGYLVTVVLFGYLFSPMLHTLTQAISTDTIYTMTFFVLLGNL-IFGHYG-VSKAVSLNAAIFGAICLASRLPTSYHAFVLLVEAAVFFVIMTE---AIFAICCMALYC---ITTIF-INFVCPFIF-VWQQQYKFNIHGPWDEAIVEEN Enthi NKYLHTEQPFPDNYI--ED-WFLGGMRVNYHLPLKDIVALSQQISTVIMYICIFLLTVYVADISMCFLS-IIIFGTVWGLVPVISTITTGYYPDSIYILSTVLFIIHI-CFFDYGEINGVLSYNAVLLASIVLASILPKNAMVFPLISLSIILFELFRHY-LL---------------CVSL-GTYVGPKFW-LKIQSLKTEVSGAWDEAVPSTQ Falba RRVLFRKQAFADNHV--GP-AFMAGLRRNTNRDFRPLATLAWHLTVVALFLSLFFMSVALGSAILATLSWIVACLVARSFVPVALAALSRYSNDTIAALGITVGAGYL-AAPPYRRTPSTFSVSLAVLGAGLAASRLEACASLSSALWAAGLFLSPLSTLLVPLPATVSSDVVY-LPLVWLG-VVFLAPAWL-IYSMRWKDEIKGPWDEAVIVVA Fomme1 QKLLWRKQPYPDNYI--PD-SFLSSLRRNANYTYWPLVTIAQHVSSIFIFLVTFVHLLVWISVLLGYLLWILVFLALLALSPVLRTLTASTSSDSIWALTACLFILNI-LLADYGRLTSVLSMNAGISASVVLASRLRDDVSVFALTLFSIQMFAMLRTR-LLALLTFCVSGVS-IHLILGF-VTFGAPLAL-VWAQRFKNEIRGPWDVAVPQVR Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 EKVLWKRQVYPDNYI--PPRLFLASLQRNPNYTYWALVSITQHLAIIFIFLAVFVRLLVCLSVFVGYFTWIMMFLALMSLSPLLRTLTAATSSDSIWALAAVLFSFNA-ILADYTGLFSVLSMNAAISASVVLASRLSTDVSVFALMLFSIQSFAMLRHR-LQLLITVGLSASA-VVLILLF-VTLVAPGVL-LWAQRYKNIIRGPWDVAVPKVN Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 KRLLWLKQPFPDTYT--DP-SFYKQWEKLKI--YRSVLQFYHMIINTMLLYIIFAWF-ILIAA--SSVSLIIIIFAMLTLSPVLKSLSKTTSSDSIWTLSAWFTTFYI-ISISAL---KILPTNILLSNVTVLSSRLDTSTQVFCFLLICIQINITMEKYFIKILCVIA----THGTVSSLL-LLFGIPHYYIHWEYK-GHPILQQWDAEKPILD Lacbi2 SRVLWKTQPFSDNHI--PPKLFLVSLQRNPNYSYWRLVAVTQHLSTIYFFLAVFIRLLVYISVLAGYFTWIMMFLALMSLSPVLRTLSAATSSDSIWALAAILFILNA-LLANYTRLTSVLSMNAAVSASVVLASRLCTDVAVFALALFSVQAFAMLRQR-LQLFLTMFMAASA-VYLMLFF-ITLIAPIIL-IWAQRYKNIIRGPWDVAVPKVN Lenti61 ERVLWKKKPYPDNYV--PR-SFLASLSRNPNYTYWHLVPISQHLASIFVFLAVFMHLLVWISVLAGYIAWILVFLALMSLSPVLKTLTAATSSDSIWALSACLFVLNA-LLADYTRLTSVLSMNAAISSSVVLASRLSDDLSVFGLILFSVQSFAILRRR-IQITLTVLTSALS-VVLCFIF-VTFIAPAVL-VWAQRYKNEIRGTWDPAVPKVN Malgl1 EKVLWRRQSFDDNYV--DA-SFLGQLRINATPTSVSLVSIGQQMASVFLFVALFVQLLVWTSLLL-----TVLGFALHALSPVVRTFSEATTNDSVWACAAVLFVGHL-AFANYSRLTSTISLNMAMCASVVLSSRLMSDVDVFALLLVALQLFGLLRDR-MR--------------------VNY----------------------------- Mellp23 RRVLWLKQPYRDNYQ--SR-SLINHLHSNKSHQYSTLVPLSSHLSSITIFIGLFLHLLIWVNLFFGYIVY------------------------SIYALTTLLISINI-LLADY-SFVSALSLNAAIFASVLLGSRLDSNAGVFSLTIFALQWFAIMRRD-MIIVLNVSLGFIA-ASVIVPIGTCLVLPAIY-SFVQRYKKDLRGPWDCAIPRIS Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 RKLLYVKQDYSDNYV--DD-TFLEELQKNANYEYWSVVIISQHISSIVIFVAIFIYLLITIGTAIGYGFWVLFFLTLLGLTPILKTLTEKTSEDTIWALTVILFLANL-AFHDYGKYPGSLSTNAAIFASVVLASRFKTNLHVFGLMSFAVQWFAMLRRQ-IRLALTIVLFLTA-TTLGMIF-LTFVCPFWL-IWIQRYKNEIHGPWDEARPKIL Mucci2 QKLLWVKQNYPDNYV--DG-TFLEELQRNVNYDYWTMVVITQQVSSVVIFIAIFIYLLIWTGSGIGYVSWFFFYITLLGLSPILKTLTSQTSDDTIWALTVCCFLANV-LFHDYKKIPGSLSTNAAIFASVLLASRLDTNVDVFGLLSFAVEWFSIFRRH-LKIGVTVAMLLTC-VALGFCF-LTFVCPYWL-IFIQKYKNEIHGPWDEARPRLQ Mydma CKVLYKHQPFEDNYT--SK-TFLDEMKKNVNYDLPRIIVVSQQLSSICLFVSIFWYLLLFALLCIGVSFRFIVSSFVFAISPILKTLTKSISTDTIYAMTTCMLLANM-LFQDYG-VSKVISLNTSIFAAVCLGSRLSSSLQVYAFVMLAVEIFAELRKD-IKIFLTETMAIFT-TLLGLVL-AHFMITFFFPIWMQRYKNNIHGPWDEARISNG Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 QKLLYIQQDYPDNYV--DE-TFLEELQKNVNYKYWTLVVVSQHFSSMLIFIGLFIHLLIISSTVILFLIWILLFAILLSFSPILKTLTETTSNDTIYALTTIFFIGNV-ILHDYGRFPDSLSINLAIFASVLLASRLPSNKSVYGLLAFAVEWFAFFLRF-LK---------------------------------------------------- Pench1 KKLLWVKQSYPDNYT--DTETFLDHLQRNPRYDFWPLVVIVQHVCSVVIFVCCFVGIIVCWGSAVGWILWFLIYFSLLGLSPILKSLTKSTASDSIWAMSCWLLIMNI-FSFDYGKFPASLSTNAAVMASTVLASRLPSTTHVFSLMLFSMEVFGIFRRQ-LRVLLTLALVIVAGGAVILTAFVMGGCSWWL-ISLQKYKNVVIGPWDPARPIIR Phybl2 RKLLWVKQDYPDNYV--DS-TFLDELQRNVNYDYWTMVGITQHISSVVIFIAIFIDLLIWTGSGAGYLFL------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 KKLLYLKQPFPDNYT--DQ-SFLSQLKRNTTYSYIKLVLIVFYISVILVVVLMFTGIPTMVTSILGFIILVLIIFILLILSPVLKSLTKSTASDSIWALSFILCVCNT-IFHDYSQYRPIISTNISLSNSIVLASRLGSTSQVFFFVLFSIQVNILFDFN-ARWTVYFIVFNFVNYLIAVLG-IVFLMPAYF-LFLQRYKNELQGPWDTAKPIIN Plicr1 EKVLWKKQDFPDNYI--PRDSFLSALKKNPNYTYGQLVAITQHLATIYIFLAVFLRLLVWISIVVGYTAWILVFLALMSLSPVLKTLTAATSSDSIWALSACLFVLNA-LLADYNRLTSVLSINAAISSSVVLASRLRDDLAVFALILFAVQTFTMLRHR-LQAILTVFLSTLS-VLLSLST-VTFIAPAVL-VWAQKHKNEIRGPWDVATPKVN Polpo RKILYEQQAFPDNHT--DE-TFLIELIQNANYDFWKIVTVTQQITCVILFVIVFFHSLVSLAMVLGYIV-ILLFGTVYALSPVLRTLTNSFSDDTIWALTFILLLAHL-FFHDYGKFSAPISLNAAIFASVLLGSRLPSNIHVFVLITYSIQTFAIARHH-IKVGLTVILCITC-SLLIVMT-ITFICPLWL-IFIQKYKNEINGPWDEAS-VIS Pucgr2 KRVLWCKQPYPDNYQ--DL-TFLNHLQRNRTDGYPTLVPLCAHLSSVMIFVGLFVYLLIWYTILVGYLVWGILIFLLLLISPVLKTLTLSTDSDSIWALSSVLFTINI-LLADYRSFPSALSINAAISASVVLGSRLPSNADVFALVLFAVEWFALMRRD-VMVVLNISLACLA-FLIAVPLGTAFILPGIY-VWLQRYKKDLGGPWDCAVPRLS Punst1 ERVLWKRQPYPDNYV--PP-SFLSELRKNPSYTYRSLVAISQHFSTIFIFLAVFVRLLVWMSVVSGYAVWILVFLALLALSPVLKTLTAATSSDSIWALSAFLFILNA-LLADYSRLTSVLSMNAAISASVVLASRLPDNLSVFALILFAIQVFSILRHR-LQTTLTAALCSLS-LFLVFGF-YTFGAPAML-MWAQRYKNEIRGPWDVAVPKVN Rhior3 QKLLWVRQNYPDNYV--DE-TFLDELQRNVNYDYWTTVVITQQISSVVIFIAIFIYLLIWTGSGIGYIFW---------LSPILKTLTSQISHDTIWALTVICFLINV-LFHDYSKIPGSLSTNAAIFASVLLASRLNTNTDVFGLLSFAVEWFSIFRRH-LKVMLTLAMLLVC-VVLGFIF-LTFICPYWL-IFIQKYKNEIHGPWDEARPRLQ Rhoto1 RKILYLKQPYPDNYV--DA-TFLADLKRNVNASLPALLPITQHLACTFLFVAVFVRLLLLICAVV-LRVWVIPLVALYLLSPALKTLTRATTSDSIWALSGTLFAVNL-LLGDYRPLPSTLSLTAALSGSTVLASRLSSNLQVFSLLLFSTLWFGLLRSS-L-LLLTWLLSTAA---LLMLTGTSVVAPLVR-GWLIRYKDRLSGPWDAAVPKVG Rozal11 ---MKIFAPFPDNYV--DS-SFLEEMQKNVNYDYMSLVLITLQISSIMIFLGVFTHLVAIFSFIFGYFIWVMLFAIVLGLTPILKTLTEDTSSDTIWAFTIILFITNL-LFFDYTQFPASVSVNAAIFASVLLASRLPTKHHVFSLCSYSVCWFVMLCKA-LKTIISISSFISA-SLLVFMF-ITFVCPYWF-ISLQKYKNEIIGPWDEA--TIM Sacce1 KRLLWLKQEYPDNYT--DP-SFIELRARQKAAARAQIRSFYQTILNTSFIYITFTYITI-FLSL-IISRTLIITFAMLTLSPVLKSLSKTTASDSIWTLSFWLTLWYI-FVISST--PSNLSTNILVALVAVLSSRLSTTIDVFCFLLICIQLNITY----LSII--------SNIIVASVF-YITVLPKWFIYWKHKRDNDLLSTWDARTPILD Salro KRCLWANDGFPDNFI--DK-DFLREEQQNRLY------DLGVQCASVVQIASFFAVLMGWASF------WFLCFIVVLLLLPLVSQLTTSISSDTLYTMAASFFIVFIAAFHEFT-----VALNAATFASICLASRLSDMTAVVVFMWFCLANIFCIRQR-VP------------RVVHVTLAVVMLCWASM-LLVLRTSSTSTGYHEHTADACA Schco3 EKVLWKKQPYPDNYI--PEGLFLSSLRRNPNYTYWQLVAITQHLASIAIFVSAFTMLLLWLSIFLGHFVWILLFLALMCLAPVLRTLTAATSSDSLWAMAAALFILNA-LLADYTRLTSVLSTNAAISSSVVLASRLAHDLAVFALTLFAVEVFAMLRRR-LQAGLTVALVLLA-LSLIFTF-VTFAAPAML-VWAQQYKNEIRGQWDVAVPKVK Schpo1 KKVLWRKQDYPDNFI--DE-SFLNGLQRNVNTDFWSLVPVSQHLSSVVIFASVFVSIVGFVSNVAAFILWILIVLTLAGLSPILMSLTKSTSPDSVWAIAVWLFLANV-FFHEYTRLHNSLSTNAALSASVVLASRLEKSINVFFFILFAVHWFAIFRKY-IHMLMTLVLIISAYIALLIFF-ISFICPIWF-IKLQRFKNEIHGPWDIALPKLG Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 KKLLYIRQDYPDNYV--DE-SFLEQMQKNVNHYYWTVAAVTQHISSIMVFTAIFVHLLLIITAFIGYAIWALLLAILIGLTPVLKTLTKEISSDTVWTLTVMMILANL-VFHDYSRFPDSLSINAGIFASVLLSSRLPSNMHVLGLMLFAIVTFVMFRRG-FRLIIITLLSPLT-VALGMLF-INLICPYWL-IHAQKYKSEIRGPWDEARIG-- Sporo1 RKVLYLRQDYPDNWV--DS-SFLSDLQRNVNASLPSLLPVTQHLACTFIFVSIFVRLLLSFSFVV-FRIWLIPLFALYLLSPALKTLTKSTTTDSIWALSGTLFAINL-LFGDCRPLPSTLSLTAALSGSTVLASRLDSNTSVFSLLLFSTLFFGLLRSS-L-LFLTWILVTTA---LGILFGSSVVAPLVR-GWLIRYKDRIRGPWDQAIPRV- Stehi1 ERVLWRQQPYPDNYV--PP-SFLSSLSKNPNYTYWPLVAITQHLSTIFIFLSTFVRLLVTTSAVAGYIIWILVFLALMALSPILRTLTASTSSDSIWALSACLFVVNA-ALADYSRLTSVLSMNAAISSAVVLASRLQDDLSVFALTLFSIQLFAILRHR-LQAILTLAISFLS-ISLVLVF-VTFIAPMIL-VRAQKFKNEIRGPWDVATPKVN Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ---MSIDSAYPDNHV--DE-SFLNLLLLNAEYSYAEAVVLTQRLVIVAVFVVAFLLTLIIINVVGGYGVFAIVYLTLLIVSPVLKTLTDSFSNDTIWALSTLFMLLHI-LTAHYEVQQTPFSFNAAIFASVLLVSRLPSAIHVFALISFAIEIFALFNHR-LHIAVTVSQACGVTGLLSLLF-ITFVAPAGL-LLIRRYKNTINGPWDEARPSLG Treme1 EKILWRRQPYPDNHV--PS-SFLSELRSLPPPPLFPLIPVTQHLAVLALFIAIFHSLVGWGTISFFYFVHILPPLLLSLLSPVLGTLTSATTSDSIWPLAGGLLSVHL-LLGDFSSLTSSLSFTSGLSGAIVLASRLPSTAHVFSLVLLAVALFARVAKS-VRLLLTISTLLVS-ISFLVAL-INFVGPAML-CWGWRWKTVRGGGWEPAVVNLR Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 RKLLYVKQDYPDNYV--DD-TFLDALQKNVNYDYWTTVVIAQHISSIVIFIAVFINLLIIAGTSLGYIFWLFFFATLLGLSPILRTLTLKTSDDTIYALTACLFIVNM-LSHDYSKFPGSLSTNAAIFASVMLASRLQTNMGVFGLTAFAVEWFAIFRRH-LQTALSIIMLAAS-VTLGITF-ITFICPAWL-IRIQKYKNEIHGPWDEAQPKLQ Ustma22 EKVLWRKQAYADNFV--AP-SFLCDLRTNSQPSLGQLTRISTRLLRVVLLALWFVHLV-----LL-----VIMAVVLLAVSPVLRTLTESTTSDSIWALSVMLFLVHL-TLADYSS--DTMSFNAAMSASVVLASRLNTDSETFTLLALGTLLFVVAERG-ANFVIAYSMTVVT-AALVVGF-ISIVCPWWI-VRAQTWKMEIKGPWDPAEPVLS Walse1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 KRILWIRQDYPDNYT--DP-EFIRHAQRLRYTPVVQVRLFYNKLLSTSLVFIAFNFITIALTV--LYLSWLVITFAMLTLSPVLKSLSKTTASNSIWTLAFWLTLAYV-GSMSPN---SNLSTNLLLAIVTVLASRLNSSTQVFCFLFICIQLNLKL----VVLV--------LSTIVLSSF-YIFVLPQWFVYWQRGYEASLSRVWESQRPILD [Cluster2977.fasta_al_trimmed; alignment length = 233] Allma1 LKLIARGKVRELYLLFVASDRLSAFDVIMKNGIPGKGKVLTGISVHWFHLI-TQ-LDGRCLLVKKLKVLPIEAIVRGYITGSGWKEYKAKGTICDIPLPK-GLVESQKLPA-PLFTPSTKAELGDHDENIHPSKVAEIIGAIKLYTKAAAY--ALERNILIADTKFEFGVLYLIDEVLTPDSSRFWPADKYQDSFDKQYVRNY-LEALPGELPADVVRETQAKYDVALKLLTG Ashgo11 LPLVARGKVRDIYLLFVATDRISAYDVIMANAIPDKGVLLTRLSEFWFHLR-AQ-LEGRSLLVQRYRLIPLEVIVRGYITGSAWKEYQERGTVHGLALPA-GLRESEELPE-PMFTPSTKAEQGAHDENISPAQAADLIGAIRLYSKCKKY--ARERGIIIADTKFEFGIIVLVDEVLTPDSSRFWNAANYQDSYDKQFLRNW-LTSN-KSMPEEIVTRTKEKYVEAYEALTG Aspfu1 LPLIARGKVRDLYLLFIATDRISAYDVIMENGIPNKGVLLTLCTKAWFHFI-TA-LQNRSMQVRKLKILPIEAIVRGYITGSAWNEYKKSGTVHGIKVAP-GLRESEAFPDGPIYTPSTKAEQGEHDENIHPDQAAAILGAVQLYKVAHAY--ALSRGVIIADTKFEFGVVVLADEVLTPDSSRFWPKDDYQQSFDKQFLRDW-LVKE-GRMTEEVVQKTAEKYKEAWERITG Aurde31 LKLISKGKVRDIYLLFVASDRISAYDVILKNGIPNKGRLLTQLSRFWFHLI-TQ-LDGRTMLVKKASVIPLEAIVRGYLTGSAWAEYKKTGTVHGIQLPP-GLVESQELPE-PLFTPSTKAEQGAHDENIHPSQAAKLIGALELYKRANSY--ARTRGLILADTKFEFGLLILIDEVLTPDSSRYWPAADYQSSFDKQYLRDW-LVSQ-GTIDGAVVEGTSKRYQEAVDMLTR Batde5 LKFIARGKVRDIYLLFVATDRISAFDVIMKSGIAGKGKILTQISEFWFHTI-TQ-LQGRSMLVRKLRILPVEAIVRGYITGSAMSEYKTKGTVCDISLPS-GLVESQQLPE-ILFTPSTKAELGDHDENIHPDKLAAIIGSLKIYKKASEY--AQSKGIIIADTKVEFGVLILADEVLTPDSSRFWPAKEYQPSFDKQYLRDY-LSSI-NKLPQTVMDNTLSKYIQVYKTLTG Botbo1 LRLLSRGKVRDVYLLFVATDRISAYDVVLNNGIPEKGKILTRLSLFWFHLI-TI-LEGRAMLVKRASVIPLEAIVRGYLSGSAWSEYKRSGTAHGIPLPA-GLSESAKLPE-PIFTPSTKAEQGAHDENISPEQAASLIGALRLYEEAAAY--ALTKGIILADTKFEFGLLILIDEVLTPDSSRYWPAGLYQVSFDKQYVRDW-LVGA-GTIADEVSKKTREKYEQVEKLLVS Botci1 LTKIAEGKVRNLYLLFVASDRISAYD-----GIPSKGALLTLLSAHWFHFL-TL-LRNRSMQVRKLKIFPIEAIVRGYITGSAWKEYQKSSTVHGIQIPA-GLQNSQAFPQGAIYTPSTKAEAGQNDENIHPSEAAKIVGAIKLYTTARDY--AAERGIIIADTKFEFGLVVLVDEVLTPDSSRFWPASKYQESYDKQFLRNW-LTTE-GAMPEDIKSQTAEKYREAFEKLTG Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 FPLIARGKVRDIYLLFVATDRISAYDVIMANGIPNKGKILTKLSEFWFHLI--Q-LEGRSLLVRKLKLIPLEVIVRGYITGSGWKEYTKSKTVHGIPIG--DVVESQQI-T-PIFTPSTKAEQGEHDENITKEQADKIVGAIDLYTKARDY--AATKGIIIADTKFEFGLIVLVDEVLTPDSSRFWSAAKYQESYDKQFLRDW-LTAN-GAMPEDIAVQTKQKYVEAYENLTG Cangl LPLVARGKVRDIYLLFVATDRISAYDVIMENTIPDKGVLLTKLSEFWFHLI-AQ-LEGRALLVRKHKLIPLEVIVRGFITGSAWKEYKAKGTVHTLPQPA-GLQESQEFPQ-PIFTPSTKAEQGEHDENISPDQAAELVGAIRLYSKCKEY--AKTKGIIIADTKFEFGYIILVDEVLTPDSSRFWNGENYQDSYDKQFLRDW-LTSN-DKMPEDIVTRTRAKYVEAFEALTG Capow LTLLARGKVRDVYLLFVATDRISAFDVVMNNGIPGKGKILNQISLFWFHLI-TQ-LEGRSMLVRSLNMLPIESIVRGYVAGSGWKEYQQSNTICGIALPA-GLTESARLPQ-ALFTPSTKAELGTHDENIHPDKAAEMIGALELYTKASEY--ALTRGIIIADTKFEFGILILGDEVLTPDSSRFWPKDKYQDSYDKQYVRDY-LESI-KTLPEDVVQNTLAKYQEVFTILTG Catan2 LKLVARGKVRDLYLLFVATDRLSAFDVIMKNGIPGKGKILTAISIFWFHLI-TH-LEGRCMLVKKLKVLPIEAIVRGYITGSGWKEYKAKGTVCDIQLPS-GLKECEQLPT-PLFTPSTKAEIGDHDENIHPSKVADIVGALTLYKRAAEY--AKTKGIILADTKFEFGVLHLVDEVLTPDSSRFWPAADYQPSFDKQYVRNY-LLAIPGELPEDVVKVTVDKYQSAARMLTG Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LPKVASGKVRDLYLLFVASDRISAYDVIMENGIPGKGALLTAMSIYWFHFI-TE-LKDRSMQVRRLQILPIESIVRGYITGSGWSEYTKSGTVNGIKMPE-GLIEGQKLPQ-PLWTPSTKAEVGGKDENISPEKAREMIGSLAIYTAAASR--AEEVGIILADTKFEFGIVVLVDEVLTPDSSRFWPKDTWQPSFDKQFLRDW-LTSN-GEVPADVVEKTAAKYREAYEKLTG Coere1 LKLLARGKVRDLYLLFVATDRISAYDVIMKSAVSGKGKILTQISVFWFHLI-TQ-LHGRSLLVKKVEVLPIEAIVRGYITGSGWKEYQKSGTVCGIELPA-GLRESQRLPA-PLFTPSTKAEYGDHDENIHPDKCAEIIGAVELYSKAAEY--AAGRGIVIADTKFEFGVVVLIDEALTPDSSRFWPSSSYQESYDKQYLRDY-LTSI-DDLPPTVLDNTLKKYIEAYVKLTG Conco1 LELLSRGKVRDIYLLLVATDRISAFDIILENGIVNKGKVLTQLSVFWFHLI-TQ-LEGRSLLIKSLNILPIEAIVRGYISGSGWKEYRQKGTICDIPLKA-GLKESDQLDA-PLFTPSTKAEIGEHDENIHPSKVAEIIGALKIYTKAAEF--ARTKGIIIADTKFEFGVLHLADEVLTPDSSRFWPLDSYQDSYDKQIVRNY-LESI-NTLPDYVVEQTLQKYIEVYEKLTG Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci LKLVSQGKVRDIYLLFVATDRISAYDVILKNGIPDKGKLLTTISLFWFHFV-TQ-LEGRAMLVRKAEVVPLEAIVRGYITGSAWSEYKKTGTVHKIPLPE-GLVESQKFPE-PLFTPSTKAEQGAHDENISPQQAAELIGALELYTTAAEY--ALAKGVILADTKFEFGLLILIDEVLTPDSSRYWPLAGYQPSFDKQYLRDW-LVSA-GVIEEDIVKGTRDRYAEAVALLTA Croqu1 LTLVARGKVRDIYLLFVATDRVSAFDIVMKNGIPNKGKLLTKLSLYFFHIL-SQ-LEARTILVKKCEVLKCEAIVRGYLTGSAYAEYLKSGTVHGIPMPD-NLADSSKFPE-PLFTPSTKADLGSHDENIHPDKLADVLGAIALYNAANDHCKSINSSLFLADTKFEFGLLILIDECLTPDSSRFWSVDEWMSGFDKQYLRDW-LKQE-GLIPDEVVKATWERYLDAFQKLTG CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 LPKVASGKVRDLYMLFVSSDRTSAYDVIMDNGVPGRGTILTMISAFWFHFV-TL-VRGRSMQVRKLKIFPVEAIVRGYLAGSAWNEYKTHGTVHGMQMPQ-GLRQCEALPQGPIYTPSTKAEYGEHDENITPEKAAEIIGALAVFKAGSAH--AREKGILIADTKFEFGLVVLVDECLTPDSSRMWPADKYQESFDKQIIRNW-LTRE-GSLPEEVRQATLGKYKDVFQRLTG Debha1 LPLVCKGKVRDIYLLFVATDRVSAYDVIMENGISSKGKILTRISEFWFHLVLSQ-ISGRSLLVRKLKLIPLEVIVRGYITGSAWKEYKNKKTVHGLSIDQDDLQESQEFTK-PIFTPSTKAEQGEHDENISPEKAAEIVGAIELYSKAKEY--AKSRGIIIADTKFEFGLIVLVDEVLTPDSSRFWNAANYQDSYDKQFLRDW-LTAN-GAMDENIIVKSKEKYIEAYESLTG Dekbr2 LPLVARGKVRDLYLLFVATDRISAYDVIMNNGVADKGKILTQLSIFWFQLI-AQ-IAGRSLLVKKLNMIPLEVIVRGYITGSAWKEYKKNGTVHGLPAPE-GLRESDPFPH-PIFTPSTKAELGKHDENISPEKAGELIGAVKLYSKARDY--AKTRGIILADTKFEFALIILADEVLTPDSSRFWSAKDYQKSYDKQFLRDW-LTAN-KTMPEDIVKKTSDKYIEAFEDLTG Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LKFISRWKVRDLYLLFVATDRISAFDVILKNGVPGKGALLTQLSVFWFHLI-ARVLSGRTLLVRKAKVVKLEAIVRGYLTGSAWSEYKKSRTVHGIPLPE-GLIESQKLPE-PLFTPSTKAEQGEHDENISPEQAKQLLGALALYAEASNY--ALSRGVILADTKFEFGLLLLIDEALTPDSSRYWSLSTYQPSFDKQYLRDW-LLSS-GEMTPEVIEGTQRRYAEVVKMLIG Fusgr1 FQKIASGKVRDLFLLFVASDRVSAYDAVLKNAIPDKGKILTLLSAHWFHFI-ST-IKNRSMVVKKLSVIKIESIVRGYLTGSAYKEYKKNGTVHGITVES-GMEEAQKFKQ-PLWTPSTKADAGEHDENIHPDDAWKEVGSLKIYDEASKY--AEEHGILLADTKFEFAKIYLVDEVLTPDSSRFWPAAGYQDSFDKQFIRNW-LTKE-GELPQDIVQATSDRYREAFLMLTG Galma1 LQLLSKGKVRDIYLLFVASDRISAYDVILRNGIPDKGKLLTQLSLFWFHFV-SQ-LEGRAMLVRRAEVVPLEAIVRGYMAGSAWSEYKKSSTVHGIKMPE-GLVEGQKLPE-PIFTPSTKAEQGEHDENISPEQAAKLIGALKLYTTAADY--ARTRGLILADTKFEFGLLILIDELLTPDSSRYWPLEGYQPSFDKQYLRDW-LVSA-GVIDEDVVRGTGERYREAVEMLTR Ganpr1 LKLIARGKVRDLYLLFVATDRISAFDVIMKNGIPGKGKILTQLSVFWFHLI-TQ-LEGRVMLVKKVKIAPIEAIVRGYVAGSGWAEYKKKGTICDISLPT-GLVESSKLPE-PLFTPSTKAEIGEHDENIHPSKVPQIVGAVQLYVKARDY--AMERGIIIADTKFEFGVLILADEVLTPDSSRFWPMDAYQSSFDKQYLRDY-LDSI-GELPQDVVHNTLEKYIQAFKLLTG Gloin1 LELITCGKVRDLYLLFVATDRISAFDVIMKNGVPGKGKLLTQMSVFWFHII-TQ-LEYRCLLVKKLKVFSVEAIVRGYITGSAWSEYKKKGTVCDITLPE-GLKESQSFEK-ALYTPSTKAEIGQHDENIHPSKVPEIIGSVKLYTKAKEY--ALSKGIIIADTKFEFGRLYLVDEVLTPDSSRFWLSLNYQESFDKQYLRNY-LLSI-DELPNDIITKTMERYIETYKMITD Hisca1 LPLVARGKVRDLYLLFVATDRISAYDVIMANPVPNKGTLLTLLTTHWFHFL-TA-LQNRCMQVRKLKVFPIEAIVRGYITGSAWKEYQQSGSVHGMKMPE-GLKESQRFPDGPIYTPSTKAEQGEHDENIHPDQAVTLLGALKLYETAHAH--ALAQGLIIADTKFEFGLVVLVDEVLTPDSSRFWSAANYQESFDKQFLRDW-LVKS-GSMDEEVVRRTGEKYREAYEKITS Klula1 LPLVARGKVRDIYLLFVATDRISAYDVIMKNAIPEKGILLTKLSEFWFHLK-PQ-LEGRSLLVQKHKLIPLEVIVRGFITGSAWKEYKKTGTVHGLPQPE-GLLESQEFPS-PIFTPSTKAEQGEHDENISPEQAARLVGAIKLYTKCKDF--AKSRGIIIADTKFEFGIIILVDEVLTPDSSRFWNGTNFQDSYDKQFLRNW-LTDN-KEMPQDIADRTRSKYIEAYEQITG Lacbi2 LSLISQGKVRDIYLLFVATDRISAYDVILHKGIPEKGKLLTNISLFWFHFV-TQ-LDGRAMLVKKAEVIPLEAIVRGYLAGSAWSEYKKSGTVHGIPLPE-GLVEGQKLPQ-PLFTPSTKAEQGSHDENISPEQAANLIGSLKLYTTAADY--AYSRGVILADTKFEFGLLILIDELLTPDSSRYWPLSGYQPSFDKQYLRDW-LVST-GIIEESVVNGTRERYKEAVDLLTK Lenti61 LHLLSKGKVRDIYLLFVASDRISAYDVILRNGVPDKGKVLTKISLFWFHFV-TV-LEGRAMLVKKAKVIPLEAIVRGYITGSGWSEYKKTGTVHGIRLPE-GLVESQKLPK-PLFTPSTKAEQGQHDENISPEQAASIIGALQLYKEAADY--ALTRGLILADTKFEFGVLILVDEALTPDSSRYWPAAEYQPSFDKQYLRDW-LTKT-GVMDDSVVEGTRKRYLEALELLTG Malgl1 LPLIARGKVRDVYMLIVATDRISAFDVVLENGIPDKGRILHGLSEFWFHLL-GQ-VEGRCMLVRRAKVLPVEAIVRGYITGSGWSEYKRSGTVHGIKLPE-GLKECEQIPNGPLFTPSTKAEQGEHDENIHPDKVAELIGAKQLYAEAENF--AKSRGIILADTKFEFGLLILVDEMLTPDSSRFWSADKYQESFDKQYVRDW-MKAN-GTLPDEIVEQTAAKYREAYKMITG Mellp23 LKLVKRGKVRDIYLLFVATDRISAFDIIMKNGIPNKGKLLTKLSVYFFHLI-TQ-LKDRTILVKKSQVLNCEAIVRGYLTGSAWKEYQQTGTVHGIQMPE-GLLESYKFPE-PIFTPSTKAEIGDHDQNIHPDQLSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSGFDKQFLRDWILNQT-EEIPKDVLQITWKKYLDGFQNLTG Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LKLIARGKVRDLYLLFVATDRISAFDVIMQNGITNKGKLLTEISIFWFHLI-TQ-LEGRSMLVKKLRVLPIESIVRGYITGSAWSEYKKKGTVCDIALPA-GMQESEAFPE-PLWTPSTKAEIGDHDENIHPSKAAGIIGSVELYTKARDY--AQEHGIIIADTKFEFGVLYLIDEVLTPDSSRFWPAATYQDSFDKQYLRNY-LESI-GTLPEDVVTKTMAKYQEAYKLLTG Mucci2 LKLVARGKVRDLYLLFVATDRISAFDVIMKNSIPGKGKILTEISLFWFHLI-TQ-LDGRSILVKKMRVVPIEAIVRGYITGSGWSEYKKKGTICDIPLPK-GLVESEKLPE-VLFTPSTKAEIGDHDENIHPSKMVEILGAVALYTKASEY--AASKGIIIADTKFEFGLLVLVDEVLTPDSSRFWPASKYQDSFDKQFLRNY-LESI-NELPQDVIENTLSKYKEAFQLLTG Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LPKLTSGKVRDLYLLFVTTDRISAYDVIMANGVPQKGAILTQLTAHWFHFI-SL-IRGRSMQVRKLKVFPIEAIVRGYITGSAWNEYQKTGTVHGIPQPA-GLQQCSPFPK-PLYTPSTKAELGDHDENISPEKAAEIVGALKVYSTAAEY--AREHGIIIADTKFEFGLIVLIDEVLTPDSSRFWPASEYQDSFDKQFLRNW-LTKE-GEMPQELAEATSARYKEAFKLLTG Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------ALSH--AEKKGIIIADTKFEFGTIVLADEVLTPDSSRFWPADSYQD---------------------------------------- Pench1 LPLIAKGKVRDLYLLFVASDRISAYDVIMENGIPNKGVLLTLCTQTWFHFI-TV-LQNRSMQVRKLRILPIEAIVRGYITGSAWNEYKKSGTVHGIKVPA-GLQESQAFPDGPIYTPSTKAEQGEHDENIHPDQAVAILGAVELYKTAHEY--ALARGVIIADTKFEFGVVVLADEVLTPDSSRFWPKDSYQASFDKQFLRDW-LVSE-GRMPDDIALKTAEKYQEAWEKITG Phybl2 LKLIARGKVRDLYLLFVATDRISAFDVIMKNAIPGKGKILTQISLFWFHLI-TQ-LDGRSLLVKKIRVLPIEAIVRGYITGSGWSEYKRKGTICDIELPK-GLVESQKLPE-TLFTPSTKADIGDHDENIHPSKMVDILGAIALYTKASEY--AASKGIIIADTKFEFGLLVLVDEILTPDSSRFWPAATYQDSFDKQYLRNY-LESI-KELPTDVIENTLAKYKEACKLLTG Picst3 LPLVTRGKVRDIYLLFVATDRISAYDVIMDNAVPEKGKLLTKLSEFWFHLILSQ-LSGRSLLVRKLKLIPLEVIVRGYITGSAWKEYKKTQTVHGLSVEA-GLLESQEFAT-PIFTPSTKADQGEHDENISPEKAAEIVGAIELYTKAKEY--AKTRGIIIADTKFEFGLLVLVDEVLTPDSSRFWNASAYQESYDKQFLRDW-LTSN-GKMDEDIVARTRAKYIEAYEAITG Plicr1 LKLISKGKVRDIYLLFVASDRISAYDVILRNGIPDKGKLLTKISLFWFHFV-TQ-LEGRAMLVRKAKVVPLEAIVRGYLTGSAWAEYKKSGTVHGIVLPP-GLVESQKLPT-PLFTPSTKAEQGAHDENISPEQASALIGALVLYVTAASY--AESRGLILADTKFEFGLLTLIDELLTPDSSRYWPLAGYQPSFDKQYLRDW-LVSV-GVIADNVVRGTRERYVDAVRMLMD Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LRLVARGKVRDIYLLFVATDRISAFDIVMKNGIPNKGKLLTQLSLFFFHVI-SQ-LEGRTILVKKSQVLKCEAIVRGYLTGSAYAEYKKSGTVHGIPMPK-NLVESSKFPE-PIFTPSTKADIGTHDENIHPDKLGEVLGSIELYKAANSHCLSSSSGLFLADTKFEFGLLLLIDECLTPDSSRFWATSEWMSGFDKQVLRDW-LKTE-GEIPQSVIDSTWNKYCEAFELLTG Punst1 LKLLSKGKVRDIYLLFVASDRISAYDVILRNGIPDKGKILTKISHFWFHVV-TQ-LEGRTMLVKKAKVIPLEAIVRGYLTGSAWSEYKKSGTVHGIPLPS-GLVESQKLPE-PLFTPSTKAEQGQHDENISPEQASKLIGAVELYNAAAEY--ALSRGLILADTKFEFGLIILIDEALTPDSSRYWPAASYQPSFDKQYLRDW-LVAA-GTIDEEVVEGTRKRYAEALEMLTA Rhior3 LKLIARGKVRDLYLLFVATDRISAFDVIMKNTIPGKGKILTEISLFWFHLI-TQ-LEGRSILVKKMKVLPIEAIVRGYITGSGLSEYKKKGTICDIPLPE-GLVDSQKLPE-VLFTPSTKAEIGDHDENIHPSKMIDILGAIELYTKASEY--AAKKGIIIADTKFEFGLLVLVDEVLTPDSSRFWPANKYQDSFDKQFLRNY-LESI-QELPEDVIQNTLEKYKEAFFLLTG Rhoto1 LKLLARGKVRDIYLLFVATDRVSAFDVIMKTGVPNKGKLLTQLSLFFFHVI-TQ-LEGRSIWVRRATVLPVEAIVRGYITGSAWAEYQKTGTMHDIKLPE-GLKESSKFDP-PLFTPSTKAEVGDKDINIHPNELPKHLPALALYSTAAAH--SLSRGLILADTKFEFGLLALVDECLTPDSSRFWPAEQWMVGFDKQFLREW-LKSG-GEIPQDIVQATWSKYEEAFEKLTG Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 LPLVARGKVRDIYLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFHLV-DQ-LEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQ-GLKESQEFPE-PIFTPSTKAEQGEHDENISPAQAAELVGAVKLYSKCKDY--AKEKGIIIADTKFEFGIIILVDEVLTPDSSRFWNGASYQDSYDKQFLRDW-LTAN-KKMPQDIVDRTRAKYIEAYETLTG Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LPLVSKGKVRDIYLLFVASDRISAYDVILNNGIPAKGKLLTQISLFWFHFV-TQ-LDGRAMLVKKAKVVPLEAIVRGYISGSAWAEYKKSGTVHGMPAPP-GLVESQKFPE-PIFTPSTKADQGAHDENISAEQAAKLVGAIALYKTAADY--AATRGVILADTKFEFGLLILVDELLTPDSSRYWPADSYQPSFDKQYLRDW-LVSK-GTIDEDVVEGTKKRYEEVVRLLVE Schpo1 FTKIATGKVRDLYLLFVATDRISAYDFIMENGIPEKGKVLTKISEFWFHLI-TE-LKDRSMLVKKYKILPIEAIVRGYITGSAWKEYQKQGTVHGLNVPT-GMKEAEAFPE-PLFTPSTKAAEG-HDENIHPDEVSKIVGSVKLYKIARDV--ALKKGIIIADTKFEFGVIVLVDEVLTPDSSRFWLASDYPDSFDKQYLRNW-LTAN-NSLPEDVVEATRRKYVEAYEMITG Sorma LPKLTSGKVRDLYLLFVTTDRISAYDVIMANGVPQKGAILTQLTAHWFHFI-SL-IRGRSMQVRRLKVFPIEAIVRGYITGSAWNEYQKTGTVHGISVPA-GLQQCSPFPK-PLYTPSTKAELGDHDENISPEKAAEIVGALKVYTTAAEY--AREHGIIIADTKFEFGLIVLIDEVLTPDSSRFWPASEY-------------------EMPQEIAQATSARYKEAFKLLTG Sphar LTLLARGKVRDIYLLFVASDRLSAFDVVMKTGIPDKGKVLTQISMFWFHVI-TQ-LAGRSMLVKKLKMLPVEAIVRGYITGSGWKEYQRKGTVCDLELPK-GLENCSKLEK-PLFTPSTKAEDGLHDENIHPDKSAQILGAIQIYETARAF--AAERGIIIADTKFEFGLLVLADEVLTPDSSRFWPADEYQNSFDKQFIRNY-LESI-NTIPDNVITRSQQKYLEAFEIITG Spipu1 LKLIARGKVRDLYLLFVATDRISAFDVIMKNGIPGKGKILTQISQFWFHLI-TK-IEGRAMLVRKLKILPVEAIVRGYISGSAWSEYKKKGTICDIPLPA-GLRESEEFEE-PIFTPSTKAEIGDHDENIHPDKLPGIIGAVKIYTKARDY--ARTKGIIIADTKFEFGVLVLADEVLTPDSSRFWPADKYQPSYDKQYLRDY-LTSI-NELPQTVVDNTMAKYVEAFTILTG Sporo1 LKLLARGKVRDIYLLFVATDRVSAFDVIMKNGIPNKGKLLTSLSLFFFHVI-TQ-LEGRAIWVRKAQVLPVEAIVRGYITGSAWAEYQKTGTMHGITLEQ-GLKESSRFEP-PLFTPSTKAEVGDKDENIHPDELAKHLPALSLYSTAAAH--SLSKGLILADTKFEFGLLILVDECLTPDSSRFWPEREWMVGFDKQFLREW-LKQG-GEIPNDIVQATWAKYEEAYELLTG Stehi1 LTLLSKGKVRDIYLLFVASDRISAYDVILQNGIPDKGKLLTEISSFWFHVV-TQ-LEGRTMLVKKAKVIMLEAIVRGYITGSAWSEYQKSGTVHGIA-------------------------QGQHDENISPEQAAQLIGAIRLYSTAQAY--AHSRGLILADTKFEFGLLILIDEALTPDSSRYWPLDAYQASFDKQYLRDW-LRSE-GTMSEEVVRGTRERYVEARDLLIG Tapde11 --------------------------------------------------M--Q-LEGRSMLVRKLRILPIEAIVRGYLTGSAWSEYRRQGTVHGIPVAP-GMRESDRFPH-PLFTPSTKADQGDHDENIHPSRVADIIGAVDLYVAARDF--ALTKGIIIADTKFEFGVLVLVDEVLTPDSSRFWPAATYQASFDKQYLRDY-LTSH-AEVPPEVVTGTRDKYIQVLQLLTG Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 LPKLSTGKVRDLFLLFTATDRISAYDVVLANGVPGKGLILTQISAHWFHLI-SL-LRGRTMVCRRLKVFPIEAIVRGYITGSAWSEYTAKGTVHGIPQPP-GLQLCSPFPNGPIYTPSTKAPAGEKDENISPEQAVSIVGSLAVYSAAAAY--ALERGIIVADTKFEFALVVLVDEVLTPDSSRFWNAAEWAPSYDKQYVRDY-LTSS-GELPASVVDETAAKYRDVFQRLTG Umbra1 LTLVARGKVRDLYLLFVATDRISAFDVIMSNSIPSKGKILTQISVFWFHLI-TQ-LDGRCLLVKKLRVLPIEAIVRGYITGSGWKEYQKKGSICDIKLKV-GLQESEKLDE-PLFTPSTKAELGDHDENIHPSRVAGIVGALELYKRASAY--ALERGIIIADTKFEFGVLILIDEVLTPDSSRFWPAASYQDSFDKQYLRNY-LESI-NELPADVIENTMSKYIEAYQLLTG Ustma22 LKLIAKGKVRDVYILFVATDRISAFDIILQNGIPNKGKLLHALSTFWFHII-AQ-VEGRSMLVKRAKVLPIEAIVRGYITGSGWAEYKRTGTVHGIKLPE-GLQESQEIPNGPLFTPSTKAEQGEHDENIHPDKVDDIIGAVALYSKAAAH--AKSRGIILADTKFEFGLMILVDEVLTPDSSRFWSADKYQDSFDKQYVRDW-LKAN-GTLPDDVVKRTEQKYREAYELITG Walse1 IKKISSGKVRELFLLFVATDRISAFDVILSSGIPGKGKLLTQISKFWFHLI-ES-LRDRTLQVKKCEIVKIEAIVRGYITGSAWSEYKKSGTVNGQAIRE-GMSESEKFDE-PLFTPSTKADMGEHDENISVEEYKKRVPAIKIYKLASEY--AATKGIIIADTKLEFGILVVVDEILTPDSSRFWPVDGYVDSFDKQFVRDW-LKSV-GVIPDDIIVKTAEKYNQGYNLLTN Zygro1 IPLVARGKVRDIYILFVATDRISAYDVIMENTVPDKGVLLTKLSEFWFHLV-PQ-LEGRSLLVHKFKLIPLEVIVRGYITGSAWKEYTKTGTVHSLPQPQ-DLRESQEFPR-PIFTPSTKAEQGEHDENISPEKAAELVGAVTLYGKCKEY--AKTKGIIIADTKFEFGIIILVDEVLTPDSSRFWNGAHYQESYDKQFLRNW-LTSN-KKMPEDIVEQTRAKYIEAYETLTG [Cluster2986.fasta_al_trimmed; alignment length = 52] Allma1 RVVIKLILFSVLLFVVPFSTYFLSNMIYSAFAAAISANVVLLGYVIVAVTEG Ashgo11 SVIVKLMFFTLAMVSFPVLTFFVSNTLVNGGLAALAANVVLFAYVIMAFSED Aspfu1 DVIYKLLGFTAAMVVGPIGMYFVTSPTVAGITAAITANLVLFGYIYVAWLDD Aurde31 GALTKLLVFSVALAVVPVGSYFLSNATYAAITAVVAANLVFAAFIVAAVSED Batde5 SAVFNLVFFSILVFAVPLVVFFYGNPTLAGIAAALSANAVVILFVVVAFSES Botbo1 SILTKLLTFSIALAIAPIGSYFISNSVYAALIAIVASNLVLAAFIFASVLED Botci1 -----------------------------------MANVVLIGYVIVAMKED Caeel ---------------------------------------------------- Canalb1 SVIQKLMFFTALMVVFPLLTFFILNSIISGGVAALAANVVLISYIIVAFTED Cangl SVIKKLVFFTVAMVVLPLLTFFTLNTIISGGLAALMANVVLVGYIIAAFTED Capow ---------------------------------------------------- Catan2 RVFVKLICFMAALAVVPIWTYYKADTSLSALSAVAAANLVVLGYVIVAVYEG Cioin ---------------------------------------------------- CocheC53 SVIWKLMSFTFAMITLPIGTYFFTNATYAGGLAALMANVVLIAYVVMAFKDD Coere1 SVVGKLVAFSLLLLVIPILAYFLSSTTPSAITAAVTANIVLAGYVYVAWVED Conco1 PVIVKILVFSLALIFLPIGSYFYTNSTYSALLAAGVANVIAIGYVIAAVIED Conpu1 STLIKLVIFSVSLAVLPLSSYFLSAFFYAAITAIFMANAVLVAYIISSVLED Copci ------------------------NTIYAAITAIVSANLILVAYIITAAAEE Croqu1 APIFKLGLVSISMAVLPIATYYGTNTTAAAVAAIVVTNVILISYVILAVLEN CryneH991 AVLYKLVLFALLMAVVPIATYFGTSTTFAAISAIAAANLILVGYVVVAFRED Crypa2 DVILKLLGFTLAMIVLPIGSYYATNSTFAGALAAIMANVVLIAYVVVAMRED Debha1 SVVQKLVFFTAAMIICPVATFFICNAIISGGVSALVANIVLIGYVVAAFMED Dekbr2 PVVKKLLLFTALMVSAPLIVFFATNDIVSGGAAAFVANVVMMLYVYIAFNED Dicdi ---------------------------------------------------- Dmel EVFLWLLAYSVLMFTLPFLGFYGVVNCWSVLTAVVVVNLVVAMYVLKAFREK Enthi ---------------------------------------------------- Falba AVVAKLVMFSIAMLALPLITYFVS-TYWAAGFTVAMVHLVLFAYIVVAVIED Fomme1 GVLLRLIVFAISLAVVPLSTYYGTDSTFAAISAVFVANVVLVAYIAISVYED Fusgr1 QVIYKLLAFTFAMVFIPIGSYFLTNSSFAGGLAAVLANVVLIGYIIVAMKED Galma1 GVLFKLIVFSVSLGVIPLASYFLSNSTFAAITAVVAANVVLVAYIISSVLED Ganpr1 ---------------------------------------------------- Gloin1 GVLFKLYSHTIMMIILPLSTYYYTKTTYAALAAAGIANVVVFSFIITAIWED Hisca1 SVIIKLVLVTVAMICAPLGTYFGTDSSYAGALAAISVNVVLIIYLIIAARED Klula1 SVIAKLMFFTVAMVVLPVLTFFWLNTLVSGGLAAAMANLVLIAYVIMAFQED Lacbi2 GVLLKLIIFSLSLGILPLTSYFASNATFAAITAVVAANIVLVTYIVMSLLED Lenti61 GVLAKLVIFALALGFVPISSYFLSNTIYAAITAIISANLVLVAYIIESVREE Malgl1 ----------VALFVAPITAYYYAK--------------------------- Mellp23 APIFKLGIVSISMAILPIATYYGT---------------LLISSLFQPL--- Mnele STVTQLLLTAVSMLVIPVSLFFVGTDVYSAIIAILAVHVILGVYCYVAYLEV Monbr ---------------------------------------------------- Morel2 STLAKLAFFTVAMIVFPIGTYFLTNATYAGISAAVMANVILIAYVAVAVMED Mucci2 GVLVKLMVFTAALFAFPIVTFFTTNTTYAGAAAALMANVIVGLYIVVAMLEK Mydma ---------------------------------------------------- Neucr2 SVIIKLLAFTFAMIVIPISSYFLTNSTYAGATAAIMANVVLIGYIIVAMAED Orpsp11 ---------------------------------------------------- Pench1 DVIYKLLGFTAAMVVGPIGMYFLTSSTLAGITAAVTANVVLFTYIYVAWTED Phybl2 VVMTKLIGFSLAMFILPIMTFYTTNTTYAAGSAAVVANVVLIGYIIVAFMED Picst3 SVIQKLVFFTGAMIIFPIFTFFVCNALISGGIAALMANVVLIGYVVVAFTED Plicr1 GVLVKLILFSVSLAVVPISIYFASNSTYAAIAAVFSANIVLAAYIVASLLED Polpo ---------------------------------------------------- Pucgr2 RPIFKLGIVSLSMAILPIGTYFGTNTTAAAISAIVVTNIILVGYIFAALSES Punst1 GVLVKLVLFAVSLAIVPLLTYYASNTTYAALTAVFSANTVLVVYIITSIFED Rhior3 ---------------------------------------------------- Rhoto1 SVVTKLAIFTLAMVLLPIGTYYLTNLTYPAIAAVTVANLILVGFVYVAFRED Rozal11 SPLQKLLVFTAVLFSLPLIILYVSNILYSSVASIVTVNLILFTFVYVASNEE Sacce1 AVINKLMLFTAAMVVLPVLTFFIINTLISGGLAAAMANVVLIVYIVVAFRED Salro ---------------------------------------------------- Schco3 ATLIRLVVFSAALGIVPLTSYFASNATYAALTAIVAANLILVSYIITSLLED Schpo1 NVLLKFVGFSVALFTLPLITYFWTQTLYAGLSAAVMVNIILALYIVAAFRED Sorma SVIIKLLAFTFAMIVIPISSYFLTNSTYAGATAAIMANVVLIGYIIVAMAED Sphar ---------------------------------------------------- Spipu1 AVIAKLLIFSFLLFSLPIATYFYTNSNYSAMAAVIVANLVVFAYVVVAFIED Sporo1 ---------------------------------------------------- Stehi1 GVLIKLVLFSASLGIVPISSYFLTNSTYSAITAIVAANIVLVAYIVLSLLED Tapde11 TVIAKLLFFSAAMVVLPLSAYYLSKTTYAAITAAVTANLVVAGYVVVAFLED Thetr ---------------------------------------------------- Treme1 AVLWKLILFAILMAVVPIGTYFSSSTTFSAIAAIIAANIVLVGYVIIAFRED Trire2 DVIYKLLGFSAAMIIVPIGSYFMTNSSLAGGMAAVLANVVLISYIIVAMKED Umbra1 SVMIKLALFTTAMFSLPILTYFQTNASYAAGSAAVVANIVLFSYIIVAALED Ustma22 GVYYKLAFFSVALFAAPISAYYFANATYAGGLAALVANLVLAAYVVAAFLED Walse1 SSITKLLAFSIALVVLPISIYFITNSTYAAISAALTANVVLMLYVGLAIYED Zygro1 SVVVKLMFFTVIMVAFPLLTFFTVNTLVSGGLAAAMANAVLIGYVVMAFMED [Cluster2991.fasta_al_trimmed; alignment length = 56] Allma1 -------------------------------------------------------- Ashgo11 DYPSQRRVAKLVSCLLGFYAGSLSLTLYAFAAAYGLALLLVVPAYGK-YRQQKLAW Aspfu1 DFYGQRIAELLAAFLIGYIYEDIHLTLWTGLAGTLVTALAVIPPWPM-YNKHPEKW Aurde31 DFEGQKLAELILAFLVGYFTQSMFACISIFGVASIALLAGLAVPWPV-FNQHPVVW Batde5 DFHGQRLVDRYVGFFTGFTTQSIMSVLVVDAIGLAVTCLVCLPAWPI-YNQNQPKW Botbo1 DFEGQRMAEQLIAFIVGFAFQSLRLSFSILGAAVLLLCLLVLPPWPY-LNQHPVPW Botci1 DFEGQRLAEFLIAFFVGFFKQDIKLALAFGLLGTIFTFAIVVPPWPF-YKKHPVRW Caeel DFQGQKVAERTIGFLVGFWTQQLSYAMFTVLGASAFTALIILPPWPFLFRKNPIVW Canalb1 TIPNQRKPYQLTSLIIGIITDSIQKICISFIIQFIILLLLVSPNWLF-QSEQSLEW Cangl DFKAQERIEKLTSFGIGFVTQSLQNLLVCFGGFFVVTLIVTLPPYSC-YKKNQLKW Capow DYHGQKLAEDLIAFAVGWMLQDFMMTLYLSAAAAAFCVLLVVPPWPF-YRRHPVTF Catan2 DFVGQYNADRILGIVSGFFLQSLSLVFKVFAVGVLIAAFAVIPPWP--YQKNPIKF Cioin -------------------------------------------------------- CocheC53 DFEGQRLADMLIAFIVGYMAQDIRLTLYIGLAGTALTFLVVVPPWPF-YNKNPEGW Coere1 DFEGQNLASTLVALAVGFALQRLDVCFYAYALCIVAAYAVVLPPWPF-FRRHPLVW Conco1 DFEGQQTATNIISFGVGFYLQDLVLMLYIFGGGVALTFLVTLPPWPF-LNRTPVKW Conpu1 DFHGQKTADDALSFVLGFAMQSLKVTFGTLGLAVVGLCLVVLPPWPM-FNQHPVQW Copci DFVGQNLVEQIISFIAGFALQSLSVTFGVYGAIVAVLALVILPAWPM-FNKNPVKW Croqu1 DFEGQRAAEKYIAFVVGYILQSMVATFSIYAAGLVIALVVVVPPWPC-YNKHPVAW CryneH991 DPQSQQLVTSYLSFVLSYLSGSVLLGVESFAAGFAVLIVATVPPWPY-LKRHPVKF Crypa2 DFEGQKLVETLISFLVGYFLQDIKLAVFIALGGTGLTFLVVVPPWPF-YKKHPVKW Debha1 DFKGQEKAEDIISLIIGWLTQDLFSTVISFLVQFAIVLLIVLPNWPL-YNKNPVSW Dekbr2 DYQGQQTVKNIISLFTGFVLNDIKYTCYVFAAFSLVTLLVSLPPFPQ-YRRHPLKW Dicdi DFEGQKLAEYIIGWIIGFIKQDFSITFYSVALGTFLSLILCLPNWKI-YCQHPLSW Dmel DFAGQGKAERWVGLVYGAFVQQFSQTVYILGAGFVLSSLITIPPWPL-YRRNALKW Enthi -------------------------------------------------------- Falba DFKGQQLAEQIYTLVTGKFIPD---AFYLFLACFGLLAVITVPSWPF-FRKNPIPW Fomme1 -------------------------------------------------------- Fusgr1 DFEGQKLVEFLISFVVGYILQDIKLAVYLGLGGTALTFLVVVPAWPF-YNKHPVKW Galma1 DFAGQSLVELIVAFCVGFAVQDLRITFGIMGFATVVLALVVIPPWPM-FNRHPVKW Ganpr1 -------------------------------------------------------- Gloin1 DFEGQKQAELIIGFIAGFLLQNLILAFQIFGGGIFLTSLFVLPPWSF-YNQHPVQW Hisca1 DFHGQRFAENLIAFTVGYAYEDVHLSVWIGLVGILIAVLVVVPPWPM-YNKHPEPW Klula1 DFESQSYTESIFSFISGYLTESIKVSGIVFVLGLIVVLVIVLPPYSA-YNKHRPQW Lacbi2 DFAGQKLVDTIISFIAGFALQDIRVTFGLFGASTALLSLVVLPPWPM-FNQHPVKW Lenti61 DFEGQKLVEQIVSFVAGFASQSLRVLFGVFALFVIVLCAAVIPPWPA-YRRHPVKW Malgl1 -------------------------------------------------------- Mellp23 DFEGQRLAEKWIAFGLGYIGQSMMITFGVYAVGVVIALLVVVPPWPC-YNRNPVKW Mnele -------------------------------------------------------- Monbr DFEGQALSEYLIGFIWGWWCQDFAQTTYVTAAGVVLACILCLPAWPF-YQRNPVQW Morel2 DFEGQRLAEQIIAFLVGLIAQDIRLSMYIFAAGVVVAAFLVIPAWPY-LRKNPIKW Mucci2 DFEGQKLAEQLASFIAGYSMHSMQMLLIVFAAGLALTALVVIPPWPM-YNKHPQPF Mydma DYEGQKKAERVVGFLWGFYIQQLSATVYIVLTGFALSCLIVLPPWPF-FRKNPLQW Neucr2 DFEGQKLVELLVSFLVGYILQDIKLALQIGLAGTALTFILVVPPWPF-YNRNPVKW Orpsp11 -----------VSFTVGFIMQSVSISCYIMLAGIIVTALVILPPWPF-YSKNPIKF Pench1 DFHGQRLAELLASFVIGYIYQDIHLTLWTGLAGTLFTAFVVVPPWPV-YNRNPEKW Phybl2 DFEGQRLADSILALIAGYSLQSLQLSICIFLIGLGTTLIAS---------TSPLAY Picst3 -------------------------------------------------------- Plicr1 DFEGQQLVDQITSFLTGFALQSLRVAFGVLGLGFVVILVAVVPPWSI-YNSSPVQW Polpo -------------------------------------------------------- Pucgr2 DFEGQRKADQLIALVAGYALQSMLLTFGIYGAGFLTALLVVVPPWPC-YNKNAISW Punst1 DFEGQKTVEHIVSFIIGFALQSLRITFGVFGIGSLAVMLVVVPPWPS-FNRHPVQW Rhior3 -------------------------------------------------------- Rhoto1 DFVGQDLVERRVAFVLGFALQNLKITFAIFTLGFLGCLAVTLPPLPA-YNAHPVKW Rozal11 -------------------------------------------------------- Sacce1 DFPSQRKTEKFVACILGFAQQSLKVLLTAYGISCVITLICVLPAYPW-YNKQKLRW Salro DYEGQKLMEGLLGFGWGYYCQRFEQTIYVTLGGVALAFLICLPPWPM-YRRHPIKW Schco3 -------------------------------------------------------- Schpo1 DFAGQLRCQKYISYIYGYLVQDSYCVIKLFLILASLVALVCLPAWSM-YNKNPLKF Sorma DFEGQKLVELLVAFLVGYILQDIKLALQIGLAGTALTFVIAVPPWPF-YNRNPVKW Sphar -----------IAVLYGYHEQSFEKSMIVFGVGAAITFLLTLPPWPF-YAKDPVKW Spipu1 DFEGQRLSERYVSFLVGFALQSLQTTLYILLAGGIIASLVSIPPWPM-YRSHPVKY Sporo1 -------------------------------------------------------- Stehi1 DFEGQKLVEQVLSYIIGLVSQSLTLTFGSFGVGTLILLVVALPQWPM-YNRNPVQW Tapde11 DFQGQKDAQMYLAFLIGFVAEDVFLTLYLFLGGVFLTFAAIVPPRPF-FKAKPVVW Thetr DLKGMVLMEWLVAFVAGWVAASFAVAMYVFGAGVLVALAVCTPDWGF-YNSDEAQF Treme1 -------------------------------------------------------- Trire2 DFEGQRRAEGFIAFNVGYILQDIVKCVYVGLGGTVLTFLVVIPPWPF-YKRNPVKW Umbra1 DFEGQRLAELIVGFLYGYVQQSLEATIMIFGIGFAITLLVTLPPWPF-YNRNPVKW Ustma22 DFQGQRLADRIVAFLLGYLTQNMQLCMLTFAASTLVVALVTVPAWPM-YKKHHVKW Walse1 DYVGQLKAERLISFISGWITSRIEVTAVVYLSGCVIAAIVIGPAWSC-YNRNTVQW Zygro1 DFPSQRYTERLVASIVGLSTQSLKNLIIVYGISIAITALVVLPAYPA-YTRRKLQW [Cluster2996.fasta_al_trimmed; alignment length = 199] Allma1 VRLLELPPDLLALVIRATLHTADRTYLLREVHTSNTVLVCTYLE-AVPSAPTMDALLNVPASLAELHAVEL--DRVLEHKYVKDMLVIVSTAARMRFVVRHLL--CLSPSKLVAHFAECVLSEFETKWIEVPEPLDPAA-IEPFSMIFYLPPSQLPG-TVPDRLRALFAIREHWELLIARVRDLAAAEQMLLKHARLVK Ashgo11 YKVLQLTEELIRVELKAVLCSADKTWAVRQKNHSNTVILMCELE-PRATAGDVETLVEATCSRAEFGGCSV--GCVISPDLLGRTLLVLATAACVGPVIETVLHRFLDLSRIARWYGVQALDEFMIKWRSFPAYFDLEL-LYG-EFIQYLSRSTLPM-DIKDRFQQLFRIQNAWREITPFIEELNGMDNFVLKYARRKK Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 YRLMELPADLYKMIIKGVICTEDKTYSLRAVVLSNTTLIVQILE-LVPVVPKYDELKDIQASDVELRVLQL--KRPLERGYLAQMLLLLNTMDAALVVASQILPWFANLESIAREIGLSILDEFLQIWADMSDSFDMRL-LEGNFILVYLPASSLPI-DPAMRFNDLFIVKARWDELAPFLADIAARDKLLLKWCRTAT Batde5 YKVLECPPELVALVIRGVLCTDQATYSLRQVETSNSMLLLSYLE-VACIPPSLSDFLEIQASEGEIGAFEI--NRLLAPTYALYILLIMLSAFQLSLVLKRCLLSNLSRTKICRLYGDQMLMQFLKSWQSVPLDWHLDQ-IKGLYLIRYFPKSLLAT-DPRMRFEDLFKIRKKWEDMLPFIEDLAARELLLLKNARISK Botbo1 YRLLELPPDLCKLSIKGVLCTATKTYTLRSVSISNSLLILEILE-LAPTVPTYDDIRDIQASDAELYILRV--NRPLPLPLLTHIILILTSITSVPVIALQVMEWFMDAKQIVRQVGIGMLDAFLAEWKTVGDAFDLSL-LLGNYLVLYFPLSSLSP-VVTQRFSDLFLTRPKWQDLMPFLQDVAERDKMLLKYCRSTT Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 YKLLQLPSKILNLYIKSALCTDSETFKLRQMNHSNTVLLLYEYE-LTEIKGDLIALEDSICSHQEFGGCEI--DYIMSADIITELLLLITKL-----MLTSIIHKFLNDLKITQWFGIVEMSEFLLNWKTLPSFYDISQ-LAG-YYILYVDPESLSE-NLSQRFKELFELDKSWDEFIPFIKKFVKVDSIILKYGKKKK Cangl YKVVQLDDTILALQFKSVLCSSNATWRLKQKNHSNCVMVMYEYE-LTKVPGTFKELLASQCSNEEAGGCIL--ECKLSDKFITRALITLVSISHLDLVIETILNKFIDKKRITYWYGLETLEEFLIKWKSMPPYFDIRE-LRGHYYIHYIDKKSLPG-DIKQRLVYLFKLQSQWDEMAPLMQDLNKFESFIIKYARIKR Capow FRLLELHDDVLQLCIKGVLATATQSFAIKQAGTSNTLLVAEYLE-ALPCKPSLEEICNVQASEQEISALLI--HRAMDFAYAHLVLLILKTIRKVPLVVEHCLRTNMSADKICRLCALYLLDEFMEAWQSVPPEFELAL-LQGLALISYFNAQELPT-DPAARFSSLFKMRPRWADILPYVNDLTTADALLLKYARGST Catan2 IRYLELPPDLLALAFRGTLHTDNATYLVREVQTSNTVLTCNYLE-VTHVPPTVRGLLRVQASEAELHAVEI--FRQLELDYVKDVLLIVTTANNLSVIVRHVMSECLCATKVPAMYAQALLIDFEEQWQAVPEPFDHAQ-LTPFSLIHYLPANELPG-TIADRLRLLFSLRNQWDEIANLVRDLTACDQLLVKQAKMIK Cioin VTLLELDKSVLQLVIRGVLCTDDSTFSLKRAVTSNSLILVDYLE-MQRIHPTLSELMNIQASEVEVNSCCI--ERLLDFGYIVECMELLQLIGRVPFILKHLLGSYLDETKICRFFAEMLLKEFLEVWKSVPSGMDEKY-LLGLALVKLFKVDQLPI-DMQQRFNSLFTVKEKWEQIEPYIEDICTVSAMLTKHARSST CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 LDAL------------------KEVFLALRSDAGGDALLSEFLAALQATMPWRSKAIPSLVR-----------D------------AYVSTP-----I---------DSQQLFTPSGVSA--------ESLLNP---------------LSRSALPH-EPRARMRHMFEARSRWAELQPFFEDLVAVDSWLLKFGR-GV Conco1 YKLIQLDSQLLPLIIKGILCTPSGTFSMKSVQTSNSTLIVNYLE-LTKVPPTSEELEDVQASNFQIRAIEY--NRLISHDYLEQILIILTSINEINIFIEHTLICFLNERSISKFFG----TEFLLSWNECPDWIELDD-ISGYYYINYLDKDDLPQ-NPKLRIQHLFKLQAKWKTLKSYLKDAVELNSFILMNCRTVP Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci FKLLELSQELAALNIKGVLCTRDKTYTIRSVDLSNTLLIVEILE-LAPAVPTYEQAQEIQASDVELRILVI--NRPIAPAYLQNILLILNLLSNASVVSTQVLAWFMDVDEVIKELGLGILRAFLSQWKEVGDTFTLKL-IAGNYLLQYFPSLALPP-DPAARFADLFLTRAKWDEISAFLNDIAERDKLLLKYCRAIT Croqu1 YLLLELPPDLLKMELRGVLTTSDKTYSLRTVQNSNSVMVCETIE-IVDVTATFEQLSSTRASDAEINVVEY--ARMVSRAYLAEILGVLGAIEPLALVLSQILGWYLDIGRIVTAVGLSLLESFLISWKAVGNAYSIDS-LNTHSILTVVSVDTLSS-EPKTRMSQLFEIRGRWDELERFVRPLTKWDELMLKYCRKIK CryneH991 YQLLELPPGLLKLTIKGTLCTADSTFLLRTVGISNSLLVCQVLE-CVPVAPTKEQLRSVQASEAELNVIEV--DLLLPSVHLKDFLILLSLLTTAPSISVPALNLFADVKRMVREVGLGILDEFMSEWQEVGETWDLKL-LEGEYLLSYFPLASLPL-QPAERFAELFLTRQRWEEMAPFLRGLTGRDKLVAKFVRIVK Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 YKLLQLTPDLLDLLLKSVLVTDNKTWKMRQMNHSNSVLLLYEYE-LSKIPG---ALMNSPISREEFCGCEI--EVILSKEFITDGLLLIPILKSDAFVTITILHKFLNNLAVAKWFGIQTLKDFLLKWKSFPPFYDLSQ-MRG-YYIQFLNPSTLTPGDMSIRVKELFQIVKEWEEFLPFIEEFIKPESIVLKYAKKKR Dekbr2 LHLVTLNNHILSLYLKAVIVTDSRTFKIRQQNQSNCLMLM-----LEDVKPTLKDLFASRASKAEFQIFEF--RDALVTTCIGKIVKLIKQVEELNKLIELCLRKFINDDLIVRQFGLEVLDDFMIELKLLPFNYKLNQALSGCYYIAYLDDSMLSE-DPVRRFAQLFSLKPQWTEIEPFIDSINKPEKFLLKFCKVKR Dicdi YRFLEANQEILDLVIKGVLCTDDKTFTIRAGHTSNSMLLVYHLE-LTEIQPSFDEIIDIQSSEKEINTLIY--KIVLSENYEFKILLILSEADNIPIIIKHCLQLYLDFNKVCIFRAKQLLEDFMDNWKDLPIEINFSM-LKGIAIVKFINESILPT-IPKARFKELFQISTRWDDIEPFIKSTISLEQFILTYSRPIT Dmel LRLLELDGHMLGLYFKGVLCTDERTYDVKGAEISNSLLLVEYFE-CREIKPTFSQLLDVQCSRGQFRAIEL--DRVMEYEYEYRIIMMLGLIDEVERVVAGLFDIYYQESLVSRIVAQNILEEFMRTWQELPEGMDLKY-LRGLGIIRSLAEELLPT-NISDRMRALFKTKKRWEEMEPYIECFTSVSTLLAKHARSLT Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 YRLMELPKELLEITMCGVLCTADKTYNIRAISVSNSFCVLQILE-LSPTVATFRQVRELQASDTELHILVL--KRPMTPSYLNNVLLMLNTMDAVSVIPKQVMSWFMDVGAVVRQLGIGVLNEFLSKWRNAGDSFDLTL-LQGNFILSYFPASELPI-NPADRFSELFLVQTRWADITPFLDDIAERDKLLMKFARSIT Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 YKLIELTPDLTTFTIKGVLCTAEKTFGMRSVGLSNTVLVVEVIE-LVPVVPTYKDAKEIQASDAELRILII--NRPIAPAFLNRLLLILNLLASASVVSTQVMSWFMDVEAVVKEVGLGILDDLFARWKSIGDTFSLNL-LSGNYILKYFPASDLPT-EPAARFSDLFLTRAKWEEISPFLSDIAERDKLLLKYCRTVT Ganpr1 YRLLELPSDLVPLIIRGVLVTGDATFNVRGLQTSNSMLILTYLE-LTLATPDTETLRSTQASDEELHAINI--DKILAPRYIKSLLTIVYAASRLDLVVEHVLHMFFSPPLISTFLGKYILDSFMLGWRKTPPDCDLKF-LEGFYVIHYISKDDLSL-EPKDRFQELFARKQRWAELLPFIRDLAKLDVILLKFARVSR Gloin1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 YKLLQLSDDLLDVKFKAVLCSEDKTWVIKQRNHSNTVILMSELE-PRLVDGTLQEFKDCPCSEKEFGGSVV--QCLLSERFMLKALIILISCDSLSIIVTTVINKFINMSLIARWYGVSALDEFMIQWKGFPPYFDICM-LRG-YFIRYMSRTTLSL-DAKERFKQLFHWQSTWADMVPYISDLNKIDTFIIKYARRKR Lacbi2 FKLLELTPELVTLVVKGVICTVDKTYSMRTVGLSNSVLVVEIIE-LAPIVPTYQDAREIQASDAELRILHI--NRPISLTYLNQLLLVLNLLTGASVVSTQVMSWFIDVDCVIREVGLGILDIFVAQWRSVGDSFSLPL-LAGNYLLTYFPASLLPI-DPAARFSHLFLTRPRWDEISPFLSDIAERDKLLLKHCRAVT Lenti61 FKLLELPADLCKFTIKGVLCTADKTYTVRSVVLSNSILVVEVIE-LVPSVPTYEDAQGIQASDAELRVLIL--NRPIARSHLTTILLILTNLAAAPIVSRQVLKWFMDVDAVIREVGLGLLGAFLAQWRKVGDTFSLTL-LSGNYLLAYFPSSELPV-DPWARFAELFLARPRWEEIAPFLADISERDKLLLKHARAVT Malgl1 YRILEVPPEVEALQFNGVLVTHDATYAVRQVSQSNSLLLCDTLE-LVRTCATRNELMSVQASEAEFHVLEL--DRRVAPDLVVDLLSLLAHVDRVPYAEAMVGDWFLARESVAQFLGLHLLIAFMDAWHHMSQD-HLAL-LQ---------------------------VRGKWTHLL--YRDIIHRPRLLRRMPTQQR Mellp23 YLLLELPPVLLNLELRGVLTTKDKTYSLRTIQNSNSVMICETIE-IFDVTSTFQSLSNTRASDEEINVIKL--KRILNLSYLAEILEIIDSSEPFMIVLLQVLSWYFDINKIVTVIGLSLLESFLTDWKTIGEPYSIDS-LKTHSILIIVPIEKLSS-EPKTRMSQLFEIRNKWEELERFVKPITQMDELVLKYCRKIR Mnele FALYNMSGYLVKNLLRGVLCTSDKTYSVRECTTSNSLLLTVYYE-LKLCRATMEDLLGIQASEEELGAIEL--NRVIDHDYKTSAVRILSLLEKVPLVTELCLRLYLSEEKICRFYGQYILNEFLEVWQDLPDGMDLTH-LRGVALISYLAVTDLPV-QPARRFAYLFTRQEKWSDIIPYLEDLITVNALLLKHCRSTT Monbr ISLWQLDDHLAQLEIKAVLCSTDATYTIKIADVTDAHYFVSYFE-LHRTAPSSAALRQLLASATEI--VEH--DFLLEPSYAREVLHILTTATQLPLAVRGVLHAHVDPIKVCRTRAIEIFSSFLNTWQNAGDECDVSM-LGGLALITYFPESELPQ-QVKARFQALFRQQPIWAEIRPYLTPLSTVEQMLLQHARLFT Morel2 YTLLEIPKTLENFHVRGVLCTPTQTFSLQRAHTSNMLIPISVLD-LIPISPTWENLQSIQASDKEIHACLI--DRLFKQRFMFDILEILSTATSVDAMVKHCIASFLSERKVSVFMGVHLLQDFMSKWNELQEHFDLKH-LAGEYIIRYFSKSQLPL-DAAARFTALFEVKPKWPEIRPFLRDLVKLDILLLKHARSVK Mucci2 YALVELTPELLEIVIKGVLCTESKTYIVRQVNTSNSLLLTSTIE-LLPCIATYYDLLSVQASENELAAFQI--DRLFDPSYLYHLFLFVTNAKQMTLVVIACINAFFDHAKICRFLGDWLLNDFLDMWNKGYDIFKLEY-IDGLYIIQYFPVAELST-DPPQRFASLFAEKPLWQEITPFLMDLADREHLLLKFARTHK Mydma YKLIELSNELIKLVIRGVICTRTQTFELRAAETTNSLLVLSYYE-VRPTRPTTDDLLDIQCSEAELQALQV--DRTLEINYQEKAFQILALVKEIPTVLLHCFKVYLSEDKVCRYYVEYILNEFLSAWSQVPDGMKSDH-LLGIALVWHFPEHNLPD-DPAQRFNFLFKTREKWKEIEPYLKNIVNLNTLLLKFTRSST Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ------------LVFRGVFCTNDKTYQMKKVQTTNMMLFISYYE-LIKISP---------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 FSVIELSEDLVRITIKGVLCTDAATYIVRQVNTSNSMLLASSIE-LIPCIATFNDLLSVQASEAELYVFEL--NRIVDQSHLHRLIVLVTYCKAIPVVVLACLRSFLDENKVCSFLGRFILEDFMEVWTKTPDVFSLEM-LKGLYIVSYFPVTELST-DPAQRFAALFAEKKLWDEIKPYIEDLAKQEGLLLKFTRIQK Picst3 YKLLQLPSDLLRLLIKSVVCTDDKTWKLRQMNHSNTVLLLYEYE-LTDSKGD--ELLESPISRQEFGGCEI--DYILSPEYITEVLTLITALRTDTVIVTTIVQKFLDNDKIAKWFGIHVLKEFLIQWKSLPAFYDLHY-LRG-YYLIYINRDHLST-TLSARFVELFQLDREWDDFVPFIKDLVKVDLMILKFGKKKK Plicr1 FKMLELPPEICKLTIKGVLCTSDKTYALRSVVLSNTVLVAEIIE-LVPAVPTYDDARAIQASEDELHILIL--NRPIAPDHLNTILLILNCLDAASVVSTQVMEWFMDIRAVATQMGLGILPEFISKWKKVGDSFSLDL-LSGNYLLTYFPSSSLPV-DPAARFADLFITRSRWEDIAPFLADIAERDKLLLKYARATT Polpo FKLLEINNEILQLYIKGILCTSDKTYIMKSAHTSNSMML-LHYE-MIEIPPHLSELESVQASNQQLLNVYYIENSLLSDRYHARIVLILTEIQSIPILLDYIFKIYLNSDLICIFRGKQILSKFMESWIDLPIGFKFEQ-LSGIAIATYFNQEELTI-VPKDRMTLMFKQNPKWPDMLPYIKPILSIETFILKFARATT Pucgr2 YLLLDLPPELLEMELRGVLTTPDKTFQLRTVQNSNSVMICETIE-LSDVTSSLSFLSQIRASDSEIHVIEL--GRMISLGYLSTILGILKSLEQFAVALLQILHKFLKLQEVVNSIGLAQLESFLATWTSLPEGLSIES-LSSHSIIIVIPIDKLSL-EPKMRMSQLFEIQPKWDQIERFLTPITKFDELVLKFCRKIK Punst1 YRLLELPSDLSNLEIKGVLCTANRTYALRSVVLSNSVLVVEVLE-LQPTVPTYLDAKHIQASDEELHILTL--KRPITDAHLLTILLLLNTLDSAPVVSEQVMGWFMDVDAVVRQIGIALLAQFLEKWRKVGDTFTITH-LAGDYLISYFPSAELPM-DHAARFGSLFLARSRWGEIAPFLSDIAERDKLLLKYARANQ Rhior3 FKLIELTPEQIQLVIKGVLCTEYKTFAIRQMHISNSVLLVSTID-LQPCLATFEELLSVQASEKELGVFEY--KRTFEKTWLFRLFSFITNAQNITLIMKAAFSVFFDEVKICRFLGEWLL------------------------------------------------------------------------------ Rhoto1 YQLLALPPALLKLEIRGVLVTATQTYSIRGVQNSNSLCICETLE-VVPTVATFDSLRSIPASDAEIRVVTL--DRPLPPSFLAQILSILSSLNGATKVARQVLAWYLDAAKLVKELGVVLLDPFVAKWKDAG-GFELSL-LAGIHLIQYLPPSSLSP-DPAARFAELFSLRPRWSEMGLFIDDLTKRDALVLKFVRKVR Rozal11 ------------------------------------------------------------MSDMELQAVEI--NRLLHSSIMDEVLLIYTICTEISYIVQHCLFITIDANKMYRIKAKILFEKFMGIWKELPDTFEIAC-LKGLALVIYLPEIDLPF-NISARLQELFSVQLEWKDITPYISRFCMIKALLMKYTNSVK Sacce1 YKLIQLTPELLDLRFKSVLCSHDKTWVLKQRKHSNTVLLMSEFE-TRETHGTLEELLESPCSALEGGGSVK--DCILSQDFLFKALVLLMSAQHLNVIIETVLNKFLRIPFIAQWYGIQALDEFLIKWKSFPPFFDIDM-LRG-YHVQYIAKSTLPM-DPKERFKVLFRLQSQWEDIKPLIEELNKIDSFIMKYARRKR Salro LVLMQVDSHVLDVSFKAVLCTDTRTYSVKHADVSNAHYVVSYFE-LRHVDPTLDALLDVRASREELHAFEH--DRVLGERYKFEVTLLLKTADGVPLVVRAVLKEMLDEAAVCRFRAQEFLDSFTETWAALPEGMNPDY-LKGLALVQYFPASSLPV-EPRARFAALFSARSVWDDITPYIAGIVTREALLMKHARGYE Schco3 FKLLELPPEVCALTIKGVLCTNDTTYSMRSVVLSNSVLVVEVIE-LSKCVPTYQSVRDVQASDAELRILQL--NRPISPSYLLRFLLVLNQLDAAPVVSGQVLGWFMDARAVVREIGLGILVALLERWREATDAFELPL-LAGNYILKYFPSSALPV-APAARFGELFLTRPKWEDITPFLTDIAERDKLLLKYARATT Schpo1 YLLLELDDDLLKIVFKSVLCTSDKTYAVRQVVQSNSYLLFSFLE-VERIYG--DQFIRVPASRNEVNFFMV--KR-LSPSYICSIIVIAQQLKILKKIKDNVLPKKLTTFWY----GRFLLDEFIQLWDNLPYPCSLNL-LKGYYFIQYLSGDQLPR-EPSRRFQSLFQLKSKWEELWSFVKDLARVEALILKYGRKQT Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar HEALELPPDMIQFYIKGVLCTLSETFMLRSADTSNSLLVSKTCYELKKTRPSRDEVLAVQASEVEL-------D------------AIASEK-----II-------FRADEILTAVGETMDDEFMEAWDGLTSPMNEQL-LRGLALIIKLDANSFSF-DPATRFQQLFAVQKEWDSIMPYVTPLC-----LAKYSRSSI Spipu1 YTLIELPKEVLDLIIRGVVCTKTMTYSISNVQSSNTMLFASYWE-LTPCQPTTKSLQNIQASDAELGALEI--DRLVDPGYQESILFLLVSADRLPLIVRHTLIRFLSEHKIGRFFGKQLLSTFLNRWREVPEPFDLPM-LQGLFLIQYYPKDLLPM-HEKPRFEALFQVRKRWEDIVPYISDLAQLDAILLKYARMFK Sporo1 YQLLALPPALLSLEIRGALVTPTQTYALRGVQNSNSLCICETLE-AVVGVASFDSLRSLPASDAEIRVVPL--DRPVPPSFLLQILSLLSALAAVSKVALSVIGWFLEADRIVRELGIVLLEAFMAKWKECG-GFDVGL-LSGVHIIQYLPSSSLSP-DPATRFSELFSLKPRWGEMGLFIDDLTKRDALVLKFVRKVK Stehi1 YRLLELPAELLQLSIKGVLCTSNKTYAIRSVVLSNSVLVIEILE-LVPAVPSYEQARELQASEQELRILVI--DRPMSPSYLHTVLLILTCLESATVVTEQVMGWFMDVESVVGEVGLGTLNAFLNKWRNVGDTFSLSL-LSGNYLLTYFPRSLLPT-DPPALFADLFLTRSKWSDIIPFLQDVAERDRLLLKYARGMS Tapde11 YILVQVTPEILDLFIKPVLCTNSSTYQLKDVQQSNSLLFLSWLEAVLKLKPTQDVLFSLPASNAEILCINL--HR-LEPDYVLKLLLLVDTINALESVLAFLLDRFIDGLEVARYTGTATLTRFAALWAQTPLPFDFQI-LGGHYIIQYFASDELSV-DGKQRIVQLLDVKERWSEMLPFLLELEVAQSLIMKHARKVK Thetr IHLMQLPEELLELTFVGVLTTESESYSVRIAETTNSMLIVEYYE-LTRTTPSTEQLLDVQASEAELGAVEM--DRTLAPEYTATLLLVITVATELTIALEHVCLLFLSAGKVARFKGVELLSEFLAAWRSVPVDFDLAT-LYGTAV------------APARRCR---------------------------------- Treme1 YQLLELPGEVLKIIIKGVLCTSDATFALRTVTISNSLLLSEILE-CVPIAGTRQQLLSIQASEVELNVVAV--DLLLPPDKLHPILILLTLLVQVPVLIRGILSLFADIIRLVREVGNGILEMFLSMWREVGENWHLDL-LKGEHLITHFPVHSLPI-NPPNRFTDLFLTRSPWEDMRPFLKGLTELDKLVARHVRVVR Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 LKLLELSPDLLELYIKGVLCTNKKTYSVRQVNLSNSLLLASTIE-LLPCLPTYDNLLSIQASEQELHAVVI--DRFIHPRYLHRIIAVITSATRISVQSAA-----FNETKLCRLLGERLLDEFLELWQKTPHPFKLEM-LRGLYIISYFPLSELPA-DPAGRFSHLFLEQKQWEDMLPFIEDLAKLDALLLKFTRSQK Ustma22 YHLLEIPNELLHLTIKGVLVSDTQTLALRAVSQSNSLLLCDTLE-LAPVVPTLKQLKSVQASPAELHIIEM--DRHISPSWTVSALVLISHLDNVPLVTALLTQFFLDTKAIVHFLGVQALSEFVHIWHELSADFHLDL-LSGYYIIQFFSYHELPA-DPAARFQDLFLTRPSWADLLPFINDLAKKDSLLLKFTRASK Walse1 FKLLELNDELVKLLFKGVLCTQDNTYSLKNRMHSNSLTMLEILE-VQKCSPDYDRISSIQASDKEIRIVCF--NRPVDPECLLRALVILNTLNKVDKYISTVIGWYLDSQAFVKEIGLSLLEKFLDDWKSSGYELNLNL-LKGYYLITYFTTSSLSK-NPSKRFQELFKTRQKWVDFIPFIRDLGELERMVMKFCRTQT Zygro1 FRLLHLTPELLELQFKAVLCSRDKTWLLRQKNHSNTVMLMFEYE-TKKVSGSMDDLLASACSEKECGGCTV--KCILSSDFLSKALVTLMSASRLKLVIKTTLEKYLDQKKVAEWYGIRALAEFLIKWKSFPPYAEIEM-LRG-WFLQYLSKNTLPS-DIKERFKMLFKLQSQWDDIAPFVEELNKIDVFIMKYARKRR [Cluster3006.fasta_al_trimmed; alignment length = 57] Allma1 GGLKLKKKKKKDTAAEIAFEEAQRKRQRERIAKMAKSHKEKVDEFNKYLESLSEHHD Ashgo11 --------------------------------------------------------- Aspfu1 --------------------------------------------------------- Aurde31 GSLKLKKKKKKSTDAEKRFDEIQKERLAKRVAKLAKTHKERVNDFNSKLEALSEHHD Batde5 GALKLKKKNKKSTEAERKFREVQRKRLDAKAEKIAKSHKERVADLNAYLESLSEHHD Botbo1 GSLKLKKKKKSKTDAERRFEEVQRQRRAERVARLAQTHKDRVHEFNSKLEALSEHHD Botci1 GGLKLKKKKKKKTASERAHEEMRRRRLNDRLKREGKTHKERVEELNRYLSTLSEHHD Caeel GSLKLKKKTKKSTEAELRFEARRQANMAERMLKQALSHREKVEKLNKQLGEMTEFND Canalb1 --------------------------------------------------------- Cangl --------------------------------------------------------- Capow GALRIKKKAKSKTPAQKKADALRERREAERILKQAVSHKDRIAEFNKKLDEQSEHYD Catan2 GGLKLKEEEEEQTAAQLAFEEAQRKRQRDRIHKMAKSHKEKVDDFNKYLESLSEHHD Cioin KPLKFKKKKKKHTPAERKFKENQDKRQMDRILKRATTHRDRVEEFNRNLDSLSEHYD CocheC53 GALKLKKKKKKKTEAEKRHDEMRRKRLEEKMRKEGKTHKEKVEELNKYLSGLSEHHD Coere1 --------------------------------------------------------- Conco1 GSLSFKKKSKKSTESELKFEKIQQERMKEKIKEVSHSHKDKVAEFNAKLSNLSEHYD Conpu1 GSLKLKKKKKKSTDAEKRFEEAQRRRLAERVAKMAKTHKDRVNEFNTKLEALSEHHD Copci GGLKLKKKKKKKTEAEKRFEEVQRQRLAQRVAKLAKTHKDRVAEFNSHLESLSEHHD Croqu1 GRLKLKQKKKKKTTAERRFEAVQKKRMAEKAKKQAKTHKDRVADFNERLEAQSEHFD CryneH991 GSLKFKKKKKKSTEAERRFLESQKRRREERAKHTAKTHKERVQEFNAKLDSLSEHHD Crypa2 GALRIKKKHKKKTETERRFEEAKRKKMLDLAEKSKKTHKERVDELNTYLARLSEHHD Debha1 --------------------------------------------------------- Dekbr2 --------------------------------------------------------- Dicdi GKLKLKKKKKKSTDAEKKHKEKLSRKEQKRIDKLVKSHKEKIEEYNKYLSSLSEHHD Dmel --------------------------------------------------------- Enthi --------------------------------------------------------- Falba GALRLKKKKSKKTPAELEYEATMRERRSQKIEQMAKSHRERVAEFNAKLEKLTEHND Fomme1 --------------------------------------------------------- Fusgr1 GALKLKNKKKKKTESQKRHEEIKKKRLLQLAESSGKTHKERVEELNTYLSKLSEHHD Galma1 GSLKLKKKKKKKTDAEKRFEEVQKRRLEQRIAKLAKTHKDRVNEFNAHLESLSEHHD Ganpr1 GKLKLKVKKKKKTKAELAFEEVQKKRQQERISKLVKSHKDRVQEFNERLEKQTEHFD Gloin1 GSLKLKKKKKKTTEAELKFEEIQRKRLDEKVEKAARSHKERVAELNRKLEEMTEHYD Hisca1 GKLKIKKKGNKKTEAERRYEEARRKRLDERLKREGKTHKERVEELNRYLSNLSEHHD Klula1 --------------------------------------------------------- Lacbi2 GSLKLKKKKKKKTEAEKRFEEAQRRRLAHRVAKLAKTHKDRVNEFNAHLESLSEHHD Lenti61 GSLKLKKKKKKSTAAERRFEEVQKKRLAEKVARLAKSHKDRVNEFNAKLEALSEHHD Malgl1 --------------------------MREQARKEAKSHKDKVDSFNAYLDSLSEHHD Mellp23 GGLKLKQKKKKKTLAERRFEAVQKKRLAEKAKKQAKTHKDRVADFNERLEAQSEHFD Mnele GKLKLKKKKKKKTKAELAFLKAQQKREGEKILKKATSHKERVEQFNEHLDNLIEHFD Monbr --------------------------------------------------------- Morel2 GSLKFKTKKKKKTAAEKRFEEIQKKRQEEKVLKSAKSHKEKVAELNRKLEEMTEHYD Mucci2 GSLKFKKKKKKKTEAERKFEEIKRQRQMERVSKAAKSHKDRVQEFNQKLEQLSEHHD Mydma --------------------------------------------------------- Neucr2 GPLKLKKKHKKKTEAERRFLEAKRKRLKEMMESGRKTHKQRVEELNAHLSRLSEHHD Orpsp11 GSLKLKKKKKKKTKAELRFEEVKLKRQLERVREYATSHKEKVALFNEKLENQTE--- Pench1 GKLKLKEKKKKKTEAEKRAEEIRRKRLHERLQREGKTHKERVEELNKYLSRLSEHHD Phybl2 GSLKFKKKKKKKTEAERKFEETKLKRQMERVAKAARSHKENVYEFNKKLEHLSEHYD Picst3 --------------------------------------------------------- Plicr1 GSLKLKKKKKKSTEAERRFEEVQKRRLAERVAKMAKTHKDRVSEFNSKLESLSEHHD Polpo GKLKLKKKKKKSTESEIKHKKQQERLEAKRIESMINSHKEKVEEYNRKLGNLPEHND Pucgr2 GGLKLKKKKKKKTRAEIKFEETQKMRLLEKAKKQAKTHKDRVADFNLRLENQSEHFD Punst1 GSLKLKKKWKSHTEAEKRFEAIQRQRMATRVAKLAKTHKDRVNEFNAKLEALSEHHD Rhior3 GSLKFKKKKKKKTEAERKFEETKRQRQMERVSKAAKSHKDRVSEFNQKLEKLSEHHD Rhoto1 GALKLK-KKKKKTEAQRRFEEVQRKRLLEKAAKAAKSHKERVAEFNEKLENMSEHYD Rozal11 GSLKLKKEKKKKTKAEMAHEKVLEKREKDRILKKAKSHKERVQEMNKFLDSLSEHYD Sacce1 --------------------------------------------------------- Salro GSLSLKKKKKKKTPAERAFAKEQAKREAARIREKAKTHKEKVQELNKKLDTMTEHHD Schco3 GSLKLKKKKKKSTDAEKRFEEIQRRRLQQKVAKLAKTHKERVQQFNEKLESLSEHHD Schpo1 GSLKLKKKKKKDTEAQKHFESVQEQRLLQKAKNERKTHKDRIDEYNRLLESQSEHFD Sorma GPLKLKKKHKKKTEAERRFLEAKRKRLKEMTESGRKTHKQRVEELNAHLSRLSEHHD Sphar TSRKIKKDKKGTTESQKKFDAIKRQREIDRIKKKAKSHKEKVEDLNQYLDTISEHYD Spipu1 GSLKLKKKKKKSTEAELKFEEIQRKRQADRISKIAQSHKERVAEFNKYLENLSEHYD Sporo1 GGLKLKSKKKKKTKAQLRFEEVQRQRLLDRAKKSAKSHKERVAEFNEQLEALSQHYD Stehi1 GSLKLKKKYVKKTAAEKRFEAVQRKRLNERVKKLATTHKDRVHEFNAKLETLSEHHD Tapde11 KSLKFKKKKKKRTPAQRKFDEIRRIRQEKEIEKTAMSHRERIEAMNTHLSKLTDVND Thetr GKGKGKKTKAKTTEAQRKFEAMQAEMEAKRLASEVKSHRERLEEYSSKLGKLSEFHG Treme1 KRRDLQKKKKKSTEAERRYYEKQKQRREERAKKAATTHKDRITELNNKLERIPDHND Trire2 GALKLKTKKKKKTEAERRYEEARKKRLLQIAQSSGKTHKERVEELNTYLSRLSEHHD Umbra1 GSLKLKKKKKKSTPAELKFEETQRRRQEEKIRRSAKSHKEKVAEFNDKLEQLSEHYD Ustma22 GSLKLKDKKKKKTEAERKFEEVRKKRMHQRIAKEATSHKEKVDAFNKYLGSLSEHHD Walse1 KGLKFKKKKKKSTESEKKFDKVQRQRLKYKVKDEALSHKEKVDQFNKKLDSLTEHND Zygro1 --------------------------------------------------------- [Cluster3009.fasta_al_trimmed; alignment length = 80] Allma1 GGRLNKVPWRL--PATRKENARKRLRAVDEVVLTLRDSRPLETEMNARNKYWVFARPGLKKGIHKVPKFTKTEREFPAGI Ashgo11 GGLLWKIPWRM--SAPQKQRQRRRLQAVDDVLKQLNLGFPAEHQMSPKDKYTVFNKRGYRKGAHKVPKWTKVSRRNPANF Aspfu1 -------------------------------------------------------------------------------- Aurde31 GGLLWKTPWRL--SRTRKANQRERLKRVDEVIETVRQSLPKEHEMLPKDKYTVFNAKGYRKGIHKVPKFTRITRVNPKGF Batde5 GVSCRKRRFGL--TIGQKYRLRQRLRGVDEVINTLVDSIPKESDMTPFEKYWVKSKKDGFKPIHWVPKWTRAPKK----- Botbo1 VGLLWKTPWRL--SPTRKANQRARLKRVDEVIETVRQSLPKEHEMDPKDKYTTFNARGYRKGIHKVPKWTRLTRVNPRGF Botci1 -----KIPWRL--SKFQKARQRKRLRAVDSVVATVDRAMPTEQEMLPKDKYTIFDRKKYRKGIHKLPKWTRLSRLNPPGY Caeel -------------------------------------------------------------------------------- Canalb1 GGYVWKFTSRL--TTTQKYKLRSRMKQVDENIKNIYQGFPKENEMTTRDKYTTFNRKNYRKPVHRVPKWTKLSRENPKYF Cangl GGLLWKVPWRM--SGPQKFRQRQRLKAVDDVVKNLTLGFPKEYQMSAKDKYTVFDKRGYRKGIHKVPKWTKISRRNPQFF Capow -------------------------------------------------------------------------------- Catan2 GGRLNKIPWRM--SATRKANQRKRLRAVDDVVNTLASSVPTEAQMNPANKYWVFARPGLKKAVHKVPKFSRVEREWPVGL Cioin -------------------------------------------------------------------------------- CocheC53 GGLLWKVPWRL--SRHQKYRHRERLRHVDSVVSTLDTAMPTEEEMLPKDKYTVFDRKRYRKGIHKVPKWTRVSRLNPPGF Coere1 GGRAWRIPWRM--SKTRKANVRKRLREVDSVIDTLMASMPRESEMLPRDKYTTFSRKNHRKSVHKVPHFTKRPRTTPKSF Conco1 GGLVWKNPWKM--SSCRKANLRKRLRDVDEVVKTLSDSLPTEAELSPREKYTVFSKKGHRLVIHKVPKFTKLPRKSPIGF Conpu1 VGLLWKTPWKL--SPTRKANARARLKKVDSVIEAVRASLPKEHEMDPRDKYTVYSRRGYRKGIHKVPKWTRTTRVNPLGF Copci GGLLWKTPWKL--SVTRKANQRARLKKVDAVIEAVRASLPKEHEMPAKDKYTVFSPKGYRKGIHKVPKFTRLTRTNPKGF Croqu1 -----KIPSRL--SSTRKANVRKRLREVDSVIQAVKESLPTEAEMDPKDKYFVFSAKGYRKGIHKVPHFTKVTRVNPKGF CryneH991 GGLLWKNPWRL--SPTRKANQRKRLKRVDDVISMVAESLPTEAEMNPRDKYTTFSKPGYRKSQHKVPKWTRLTRENPKGF Crypa2 GGLLWKIPWRL--SKFQKRRHRLRLRHVDGVVATLDRAMPTEEEMRPKDKYTIFDRKRYRKGIHKLPKWTRVSRLNPPGY Debha1 GGYLWKVAPRM--SGPQKYRLRRRMKTVDENIEVLYKSFPKEHEMTPKDKYTTFDKKDYRKSIHRVPKWTKLSRENPKYF Dekbr2 GSLLWKRPWRL--SKTQKFRQRKRLQQVDENIENLYEGFPKEKDMEPKDKYTVFDKKGYRKAIHFVPKWTKISRKNPKNF Dicdi -------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------- Falba GGLVHKIPWKL--NHSRKANVRDRLAMIEKTVAAVRSVLPK----TPREKYFVEVRPSGLKGLHKIPHFTKLPKTK---- Fomme1 SGLLWKTPWKL--SVTRKANQRKRLKQVDSVIEAVRASLPKEHEMPARDKYTVFSAKGYRKGVHKVPKFTRLTRTNPKGF Fusgr1 GGLLWKVPWRM--SKFQKRRHRLRLRAVDDVVATVDAAMPTEAEMLPRDKYTMFDRKRYRKGIHKLPKWTRVSRVNPPGY Galma1 GGLLWKTPWKL--SVTRKANQRARLKKVDAVIEAVRASLPKEHEMPARDKYTVFTPKGYRKGIHKVPKFTRLTRTNPKGF Ganpr1 TGRCWSRPWKM--NSTRKRNVRKRLREVDDVVSTLVESLPTANTLSPKEKYFVFSRKTDVKGLHLVPHFTKVP---PRGL Gloin1 GGLLWKNPSKM--SRTRKANVRKRLRAVDAVIEAVDNSLPKESEMTPRDKYTVFSRKGYRKSLHKVPKFTKVTRRTPPGF Hisca1 GGLLWKIPWRL--SAPQKARQRKRLRAVDKVVDTVSAAMPREEEMLAKDKYTIFDRKKYRKGIHKLPKWTRVSRVNPPGF Klula1 GGLLWKVPWRM--SGPQKARQRDRLRSVDDVLSTLKLGFPKEPEMSATDKYSVFNRKGYRKGIHKVPKWTKLSRRNPRHF Lacbi2 GGLLWKTPWKL--SVTRKANARSRLKKVDAVIEAVRSSLPKEHEMPAKDKYTVFSPKGYRKGIHKVPKWTRLTRTNPKGF Lenti61 VGLLWKTPWKL--SRTRKANVRARLKRVDSVIEAVRASLPKEHEMPPKDKYTVFSRKGYRKGIHKVPKWTRMTRTNPKGF Malgl1 SGLLWKNPWRM--SATRKARVRQRLRDVDTVIDTIRTSLPTESEMHPRDKYMVFSPANFRKSVHKVPKFTRKTRVNPRGF Mellp23 -----KIPWRL--SSTRKANVRKRLREVDSVISAVKESLPTEAEMTPKDKYFVFSAKGYRKGIHKVPHFTKVTRVNPKGF Mnele -------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------- Morel2 GGLLWKARMKMDLSPTQKANIRKRLKAADDVVMKIQQSEPTEAQMPAKDKYTVFSRKGYRKSVHKVPHFTKVARTAPAGF Mucci2 GGLLWKNPFRM--SATRKANVRKRLKAVDDVIATVAESLPKESEMLARDKYTVFSRNGYRKSVHKVPKFTKLTRTSPPGF Mydma -------------------------------------------------------------------------------- Neucr2 GGLLWKIPWRM--SKFQKLRQRRRLRAVDNVVATIENAMPTEAEMLPKDKYTIFDRKRYRKGIHKLPKWTRVSRVNPPGY Orpsp11 -------------------------------------------------------------------------------- Pench1 GGLLWKTPWRL--SSPQKARQRKRLRSVDRVVDTVSAAMPREEEMLPKDKYTLFDKKSYRKSIHKLPKWTRVSRVNPPGF Phybl2 GGLLWKNPFRM--STTRKANVRKRLRDVDQVIATVAESLPKECEMSPRDKYTVFSRAGHRKSLHKVPKFTKKTRTSPPGF Picst3 GGYLWKVAPRL--SGPQKYRLRNRMKQVDQNIENIYTAMPKESEMAPRDKYTTFTKKTYRKDLHLVPKWTKKSRENPKYY Plicr1 GGLLWKTPWKL--SPTRKANARARLKKVDSVIEAVRASLPKEHEMPARDKYTVFSPRGYRKGIHKVPKWTRLTRTNPKGF Polpo -------------------------------------------------------------------------------- Pucgr2 GGRLSKIPWRL--SSTRKANLRKRLREVDSVIQAVQESLPTEADMTPRDKYFVFSAKGYRKGIHKVPHFTKITRVNPKGF Punst1 VGLLWKTPWRL--STTRKANARKRLKQVDAVIEAVRASLPKEHEMPARDKYTTFSKKSYRKGIHKVPKWTRLTRTNPKGF Rhior3 GGLLWKNPFRM--SATRKANVRKRLKAVDEVISVVAESLPKESEMLPRDKYTVFSRNGYRKSLHKVPKFTKKTRTSPPGF Rhoto1 GGLLWKIPYRL--SPTRKTRQRLRLKAVDDVIAKVQASLPTEQEMPARDKYTVFSRRNYRKGIHKVPHWTKVTRVNPKGF Rozal11 -------------------------------------------------------------------------------- Sacce1 GGLLWKIPWRM--STHQKTRQRERLRNVDQVIKQLTLGFPKENQMSSKDKYWTFDKVGYRKGIHKVPKWTKISRKAPKFF Salro -------------------------------------------------------------------------------- Schco3 GGNLWKMPMKL--SVTRKANVRSRLKKVDAVIEAVRASLPKESEMPARDKYTVFSRRNYRKPIQFVPKWTRLTRVNPKGF Schpo1 GGLVHKVPWRL--SQRRKYRHRQRLRAVDEVVDVLRTAHQPESQMSPKDKYTMFTRQGFRKGVHKSPKWTRSTRVNPTGF Sorma GGLLWKIPWRM--SKFQKLRQRRRLRAVDSVVDTIENAMPTEAEMLPKDKYTVFARKRYRKGIHKVPKWTRVSRVNPPGY Sphar -------------------------------------------------------------------------------- Spipu1 GGLVWKRRFRL--TDTQKYRHRKRLRAVDEVVDTLVESAPKESEMSPLEKYWVASKRNGIKPIHWVPHWTKVPRRGPPGK Sporo1 VGLLWKMPYRL--SKTRKFRQRLRLKSVDQVISTLASTLPSEQEMPPRDKYTIFSRTGYRKGIHKVPQWTKVTRTNPKGF Stehi1 GGLLWKSPWKL--SVTRKANVRARLKKVDAVIEAVRASLPKEHEMPARDKYTVFNPRGYRKSVHKVPKFTRITRTNPKGF Tapde11 -------------------------------------------------------------------------------- Thetr -------------------------------------------------------------------------------- Treme1 GGLLWKSPFRL--SPTRKTNHRQRLKAVDSVISAVEESLPKEGEMNPRDKYTTFTKRGYRKSVHKVPKWTRLTRENPTGF Trire2 GGLLWKIPWRL--SRFQKRRHRLRLRAVDSVVATLDAAMPIEEEMLPRDKYTMFDRKKYRKGIHKLPKWTRVSRVNPPGY Umbra1 SGLLWKNPFRM--SATRKANVRKRLKAVDDVIATVSASLPRESEMLARDKYSVFSRKGHRKSLHKVPKFTKKTRTSPPGF Ustma22 GGLLWKNPWRL--SSTRKNRVRQRLRAVDNVIATLEQSIKPESQMSPNDKYTTFSKRGFRKSVHKVPKWTRKTRENPVGY Walse1 GGLVRKVPWRL--SSTRKFRVRERLRDVDQNIQAIKDSLPSESAMPPRDKYFTFNKPTYRKGVHKVPKWTKITRTNPAGF Zygro1 GGLLWKVPWRM--SSHQKQRVRDRLRDVDGVVKQINLGFPRESQMSSKDKYSVFDKRGYRKGIHKVPKWTKLSRTNPRFF [Cluster3016.fasta_al_trimmed; alignment length = 137] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 SLDWFNVLIAQTIQKFREEALNDFISVKITELDIGDDFPIFSNLEAKIDIDLS-DRLTLGIETRLLMNYPKASLPVKLTVSMLRFQACLTVLVFSFPD-YRMEFDIKSLIGARSKLENIPKISSLVEYQIKKWFMDR Aspfu1 SLDWFNVLIAQTIAQYRQTALTAALNITVTDISLGEEFPIFSNLQALMDVDLSDDNLSIAVETQLLLNYPKAILPVALSISVVRFSGTLCIVAFSFPD-YRLDLSVRSLIGSRSRLQDVPKVAQLVEARVHAWFEER Aurde31 SAEWLNLIMYQIAQAYREDLIERWLNIRVHAVDLGSGCPHISDVKIKLRLSYT-DTVSVSLSTSVLFNYPAARLPVSLSISLSLFSSLATIISVSLRS-FTLDLKTTSLLGSRAKLADVPKLHEMIQARVRSALAEK Batde5 SCNWLNILIAQFLLTLRTDALDSILNISITNFSLGEEYPTLKNMKIHVDFSFD-DQLTLGIDTQMLINYPKAALPISIVLSIVKFSGTFVIVSVSVDD-FLLDFDVRSLLGHRTKVKDLPKLTSLISNSLRSVFISE Botbo1 SAEWLSELAEQVIQVYRAEWVERWANVKIHAVDLGVGAPRLFNKEIQFDITYR-DTFAVSLSTALIFNYPTARLPISVNLSLSLFSGVMTLLTLTLPS-FTLQFQMTSLLGSRAKIADIPKVHQLIEARIRHAIARR Botci1 SLDWFNVLIAQTIAQFRADALTKVLNIKVTELSLGEDFPIFSNLQARMDVDLS-DFITLAVETKLLLNYPKAVLPVALAVSVVRFSGTLSILAFCFDD-YRLDLSIRSLVGSRSRLQDVPKIAQLIEARLHTWFDER Caeel ----------------------------------------------------------------------------------------------------------------------------------------- Canalb1 SLDWFNVLVAQTISQLRSEALNNFLTINLTEIDIGDDFPIFSNLEAKIDVDLS-DTLTLGIATKLLLNQPRAVLPVSLTVSIVRFSGCLTVLMFSFPD-YRLEFIVKSLIGSRAKLQDVPKISSLIENQLRTWFIER Cangl SLDWFNVLLAQMIQQFREEALDSFIQITITELDIGEDFPIFSNLEAKIDIDLN-DKITFGMSTRLLLNYPKAALPIDLAVSMVRFQACLTVLVFSFPE-YKIDFDIKSLIGARSKLENIPKISNIIEYNIKKWFAER Capow TCLWLNVVLARIYHDVTSSDLKTSLNISVESLVLGDAIPVIENLRAVFTIDFQ-GEIALTCNTSLVLNWPVASTSVTATVRLTSVRAKVQLFSFAFEE-PQFSFTTDTAIGQRVHLSS-EKLASIITTNVRKALINK Catan2 ----------------------------------------------------------------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SLDWFNVLIAQTIAQLRADALTDVLNIRVTEIALGDEFPIFSNLQARMDVDLS-DVITIGIETTLNLNWPKAVLPVALAVSIVRFSGTLVVLAFTFDD-YRLDLSVRSLVGSRSRLQDVPKIAQLIESRVHAWFDER Coere1 SCNWLTVFLAQIIAKFRADAISEALNIRITQFSLGSDFLRIVSMRAELELALH-DEITLGFNTRVLVNWPRAALPVSMAISLVKFTGTVAILSVSIPD-YVLEFDVQTLIGSKAKVQNLPMLTSVISRKLQAAFAKE Conco1 TVDWFNVLVGQILHQYRTDLIETVLNITLTDLSFGQEFPNMSQLYLEACVEYR-DRITIAFDTSLQVGPPGAALPVSLSVAIVRFNGRVVIILFSIPD-FQLDLDVNSLLGHKTKVKDLPKLASMLVYRVKVLIYQY Conpu1 SAEWFNMLAQQITEVYRSKLIEEFANISVHTVDLGISAPQVSNSNVQLDVTYT-DVVSISLSTAYLFNYPMARLPVSITIALSLFQASIILLTFSLPD-FTLDVKTSSLMGSRAMLKDVPKLHELIQQQIHRVLATR Copci SLDWFNLLLQQVANVYRSKLIEAFANIKIHSVDLGAGAPTLFNPEIEFDAVYE-DTLSLSLSTSYLFNYPTARLPISLTISLSQFKSSIRVLTFTIPD-FVLDLTTTSLMGSRAKLANVPKLHELIQHQVRRVLGGR Croqu1 TADWLNVLVAQAIVAYRSLVVEEALNITVTEVDFGDQFPLCSNMRIEVDVDYA-DHVTLAIETKVVINFPTAVLPVSLGLTLNQISATIMAILLSLPD-FTLSMSTTSLLGARAKLEDIPKVEQLILGRLRGWIVDN CryneH991 SSDWVNVLLAQILQGYRNDLVEGWLNIDVTSLSLGTSYPLLSNLRAEIDVDYL-DSLSMTLSTAVLINFPKAVLPVTLGVELVSIGGTMSVIHANLPD-FHLNLKVTSLLGSRAKLQDIPKLEQLIVSRLRNLIQDR Crypa2 SLDWFNVLVAQTIAQFRSDALTKALNIRVTELNLGEEFPIFSNLQARMDVDLS-DMITLALETKMLLNYPKAVLPVALSVSVVRFSGTLSIMTFSFDD-YRLDFSLRSLLGSRSRLQDVPKIAQLVESRLHKWFDER Debha1 SLDWFNVLIAQTISQLRTEALNEFLTIKLTEIDIGDDFPIFSNLEAKIDVDLS-DTLTLGIETRLLLNHPRAVLPVQLSVSIVRFSGCLTVLMFSFPD-YRLEFTVKSLIGSRAKLQDVPKISSLIESKLRSWFIER Dekbr2 SLDWFNVLLAQFIMQVRREALDKAFNINITEVNIGNDFPILSNIQAKIDVDVS-DTLTLAAETSFLINSPKASLPVQLKVSIVRFSGCLTLVIFSFPD-FRLEFDIKSLIGSKAKLEDMPRIRSIIENALRKWLIDR Dicdi ----------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------- Fomme1 PAAWFNLILRQVVETYRSKLIERYANICILSVDLGSSAPRISNDQAVFDMTYV-DTLSVSLSTSVLFHYPIVRLPITLNVALSLFSSSVTILTVSLSN-FTLELNTTSLMGSRAKLADVPKLHEMIQAQVRRILSER Fusgr1 SLDWFNVLIGQTIAQFRSDALSKALNIRVTELSLGEDFPILSNLQARMDVDLS-DMLTLAVETKLLLNYPKAVLPVALAVSVVRFSGTLSIMIFNFDD-YRLDFSIRSLLGSRSRLQDVPKIAQLIESRLHRWFDER Galma1 STEWFNTLLRQIVDVYRSKLIENYANITIHSVNLGVSAPSLFNTELEFDASYT-DTISLSLSTSYLFNYPTARLPISLTISLSQFKSSISVLSLTIPN-FVLDLTTTSLMGSRAKLANVPKLHELIQHQVRRVLAAR Ganpr1 SCTWVNLLLAQLVSRCRQDRVGEMSNITITDFSMGDEFPSVKVVRVELELSLH-DNISLGLDTFVVVNWPKASLPVGITVSVVKFEGKIALTEISLPD-FQLDLDVRSMVGHRTKVKDLPRLTSMISAWIKERLVGP Gloin1 STAWLNVLFAQTIYQYRNDAVDKILNIEVTRLDIGEEFPIFKNMRVEVDCDYS-DHITLGIDTQILLNWPKAVLPISLVISVIKFSATITLILVSVPD-FILEFNVQSLIGSRSKLEDVPKITHIIISKLRNAFCEN Hisca1 SLDWFNVLIAQTIARYRQTALSEALNIKVTDISLGEEFPIFSNLQALMDVDLSDDNLSLAVETSLLLNYPKAVLPVALAVSVVRFSGTLCILAFSFPD-YRLDLSVRSLIGSRSRLQDVPKVAQLVEARMQAWFEER Klula1 SLDWFNVLIAQTIHQFREEALNDFIEIKITEVDIGDDFPIFSNLEAKIDIDLS-DRLALGIETKLLLNYPKAALPIKLTVSIVRFQACLTVLMFSFPE-YRMELEVKSLIGARSKLENIPKIASLIEYQISKWFVER Lacbi2 SAEWFNVLLRQIVDVYRSKLIENYANIEIHSVDLGVSAPELFNAETEFDATYT-DTLSLSLSTSYLFNYPMARLPISLTISLSQFKSSICILTISIPN-FVLDLSTTSLMGSRAKLANVPKLHELIQHQVRRILAAR Lenti61 SSEWLNVFLQQVLEAYRVKLVEEFANIKVHSVDLGSSAPRLSRPEIDYDMSYM-DTASISISTSVLFNYPFARLPVSLTISLSLFASSVRLITFTLSD-FTLDIKTTSLMGSRAKLEDVPKVHELIQHQIRRVIMEK Malgl1 SLDWLNVLVAQLLMSYRMSILERVLNLVVTDIDMGCRYPTFSHTLVEIDFEYM-DALTLGIDTRMWLHFPQGSLAANLCMRVERFAGTLVL--VCLPN-FVLDAHLSTILGSKSKLQDVPKIEELFLARLRSWLEHN Mellp23 TADWLNVLVAQAIVAYRSLVVEEALNITVTEVDFGDQFPLCTNMRIEVDVDYS-DHVTLSIETKVVINFPTAVLPVCLGITLNQLSATVMAILLSLPD-FTLCMSTTSLLGARAKLEDIPKVEQLILGRLRGWIVDN Mnele ----------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------- Morel2 SLDWMTVLMAQAIAQYRDDSLAEALNIRVTELNLGEDFPVLSRVRAEIDIDFN-DQIMLGIETSVLINWPRAALPVSLVLSVVKFQATITMISISTPD-FDLEFGVQSLLGARTKLEDVPKVTDLITSKLRGFFIDK Mucci2 STDWLNVLLAQAILQYREDAVDDILNIHVTELNLGEEFPIFSNMVSEIDFEYN-DQVTLGIETQLILNWPKAALPISLVLSVVRFSGT---IAISSSD-FVLDLKVQSLIGSRTKLEDIPKLRDLIQTKLRNVYIDK Mydma ----------------------------------------------------------------------------------------------------------------------------------------- Neucr2 SLDWFNVLIAQTIAQFRSDALSKALNIKVTELSLGEDFPIFSNLQARMDVDLS-DMITLAVETKLLLNYPKAVLPVALAVSVVRFSGTLSIMIFTFDD-YRLDFSIRSLLGSRSRLQDVPKIAQLVESRLHRWFDER Orpsp11 SCDWINVIIALFIESYRRDNLNNYLS--------------------------------------------------------------------------------------------------------------- Pench1 SLDWFNVLIAQTIAQYRETALTAAMNIKVTDISLGEEFPIFSNLQALLDVDLSDDNLSIAVETSMLLNYPKAIIPIALSVSVVRFSGTLCIVAFSFPD-YRLDLSVRSLIGSRSRLQDVPKIAQLVEARVHAWFEER Phybl2 STDWVNVLIAQAIMQYRDDAVDEVLNIHVTELNLGEEFPIFSSMRAEIDFEYN-DQITLGIETQLILNWPRAALPVSLVLSVVKFSGTLTIIAISSSD-FVLDLNVRSLIGSRTKLEDIPKLTDLITSKLRSLYIDR Picst3 SLDWFNVLVAQTIAQLRSEALNNFLLINLTEIDIGDDFPIFSNLEAKIDVDLS-DTLTLGIETKLLLNHPRAVLPVQLSVSMVRFSGCLTVLMFSFPD-YRLEFTVKSLIGARAKLQDVPKISSLIENRLRAWFIER Plicr1 SAGWFNVILQEVAETYRSKLIEDYANIKIHSVDLGVSAPRVSNNTIEFDSTYT-DTISVSLSTSYLFNYPMARLPVSLTISLSLFESPITVLTLTIPT-FTLDLKTTSLMGSRAKLANVPKLHELIQHQVRRILAAR Polpo ----------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 TTDWLNVLLAQAIIAYRSLVVEEAMNITVTEVEFGKEYPVCTNMRIEIDIDYS-DRVTLAIETKVVVNFPTAVLPISLGLTLNQLSATIMAILMSLPD-FTLSMTTTSLLGSRAKLQDIPKIEQLILGRLRGWIVDN Punst1 SADWFNLLLRNVLDAYRSKLLEEYANIRIHSVDLGSSAPRFSNSEVELDMVYK-DSVSVALSTGVLFNYPLARLPVSLTISLELFQSPVVFLQISIPDGFTLNIKTTSLIGSRAKLADVPKLHELIEHQIRRLVAQK Rhior3 STDWLNVLLAQVILQYRQDALDSVFNIHVTELNLGQEFPIFSRTRAEIDFEYS-DQVTLGIETQLILNWPKAVLPVSLVLSVVRFSGTLTIIAISSSD-FILDL--------------------------------- Rhoto1 SLDWLNILLAQLISSYRS-LIEESLNIEVDEVELGEGFPALTDVRVELDLEYT-DTVVLSVSTRVVMNFPRAVLPVSLSITLERFSGTVTVVHLSLPD-FDLVLSTSSLLGSRAKLQDVPKVEQLLKARIRAAIQDK Rozal11 TIEWLNSLVRSILFRFKTSSMDEILNFVITNLEFGKSPPRIEKVDYEILFSVK-DCANIGIETELILNWPQATLPISLFFKLNEVKGKAIIFEFCFEE-PFIDIGIGSLIGNKTKLKDVAKLSRLIRIKLRNVIKQK Sacce1 SLDWFNVLVAQIIQQFRSEALNDFIGIKITELDTGDDFPIFSNLEAKIDIDLN-DHLTLGVETKLLLNYPKAALPINLVVSIVRFQACLTVLMFSFPE-YRMEFEIKSLIGSRSKLENIPKIGSVIEYQIKKWFVER Salro ----------------------------------------------------------------------------------------------------------------------------------------- Schco3 SAEWLNSLVKQILNVYRSKLVEAYANVTIHSVDLGVRAPRFSNNITEFDVEYT-DTVSVSLATSYLFNYPAARLPIELTVSLAVFKSTISILTLTIPT-FTLDLKTNSLMGSRAKLANVPKLHELIQHQVRRVLAAR Schpo1 SLDWFNVLIAQALIQFRYDALETVLNIYVRDLSLGDGFPVFSHLRAEMLVSLT-DNINCTVDTKLLLNFPKATLPLSITVRICKFVGKIMIMNLSFPN-FVISLQVSSLVGARSKLQDIPKITQLIESRIRQWFTNR Sorma SLDWFNVLIAQTIAQFRSDALSKALNIKVTELSLGEDFPIFSNLQARMDVDLS-DMITLAVETKLLLNYPKAVLPVALAVSVVRFSGTLSIMIFTFDD-YRLDFSIRSLLGSRSRLQDVPKIAQLVESRLHRWFDER Sphar TCDWLSAVLQSVYVSLRHR-IKYALSIRIVDFTLPTEMPQLREMTLLARVGWV-GTMSVSVEVDVVLNYPVAVMPLALSVTLQRFEGLMRIMSVCFGD-PILDFQLGTVIGAATRVHDPPKLLEIVVGRVHRTIHDK Spipu1 TCDWLNVLLAQAITKYRNDSLDEVLNIHITDFSLGEEFPIIQKLRTEIQFEFD-DQITLGVETQVLVNWPKAALPVALTLSVVKFSGTVAVISISIDD-FSLEFEVRSLLGHRTKVKDLPKLASLITSKLRSVFIEE Sporo1 SLDWLNVLIAQLLSSYRL-LIEEALNIEVEEVVLGEGFPQLSSLRVEVDLDYT-DKVSLSLSTRVVVNFPRAVLPVSLSLTLQRFSGTVTIIHLSLPD-FTLDLSTSSLLGSRAKLEDVPKVEQLLIARIRAVIQDR Stehi1 STEWFNLVLRQVVESYRSRLVEDFANIRVHSVDLGVSAPRLSNPQTDLDLTYT-DTVSISLSTAYLFNYPMARLPVSVTISLSLFSSSISILTIRIPT-FTLKLTNTSLLGSRAKLADVPKLHELIEYQIRRQIAQR Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------- Treme1 STGWLNVLLSQILQGYRNDLVERWMNIQVTALSLGSSFPLLSNIRAEIDVDYS-DSLSLSLSTSVLINFPRAVLPVSLGVELASIGGTLSLIHACLPD-FHLHLKTTTLLGSRAKLQDIPKLEQLVLSRLRAVIQDR Trire2 SLDWFNVLIAQTIAQFRSDALTKTLNIRVTELSLGEEFPILSNLQARMDVDLS-DMLTLAVETKLLLNYPKAVLPVALSVSVVRFSGTLSIMAFNFDD-YRLDFSIRSLLGSRSRLQDVPKIAQLIESRLHRWFDER Umbra1 STDWLNVLLAQTMSQYRDDAIDEVLNIHVTELSLGDEFPIFSNMRAEIDFEFS-DQLSVGIETQLILNWPKAALPISLLLSVVRFSGTLTIVAISSSD-FTLDFAVRSLLGSRTKLEDIPKLTDLITSKLRNVYMDR Ustma22 SADWLNVMFAQAIAGYREDVMEEILNIRVTEADFGDAYPIFTNTRIEIDVDYS-DQITLAIDTKLLINFPKAVLPVSLGLTIVRFSGTLAILHFSLPD-FALEASATSLLGSRAKLQDIPKIEQLLISRLRGWIMDR Walse1 SVEWINSLLSGYYGVYR---IENLLNIEVNNFEIGYKYPQLSN--CLIDFDYN-DQLLVETSSKFIINYPRASIPIDISIKLIRFNGCVSMMVVSLSN-YNLILKCQSQLGSKAKLQDIPKLEEIIINNIDNLLTTK Zygro1 SLDWFNVLIGQTIQQLREEALNAFIEIKITELDIGHDFPIFSNLEAKIDIDLN-DRLAVGIETRLLLNYPKASLPINVTVSIIRFQACLTVLMFSFPE-YRMEFETQSLIGARSKLENIPKIGSLVEYQIKKWFVER [Cluster3023.fasta_al_trimmed; alignment length = 171] Allma1 -----------------------------------------------------------------------------------------PQDASNVIVSVGSDADGKLHGLVFRADNKRIAVASWSSGV-HILS-RNGKHLATLPCNVGASAV-AFSAAGKADGAVLLWRV Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ILRGHLISADADGWDLVMKRHGRDHKLRVWRHSLPVNALNFCAFSPLIAVPNALNSGLPLERRVCTGMVMAV-HLFVA-SAYEDGHVMLSQPVLSIDVFLSSSADALLQGLRIRSDGKIFATAGWDSRI-RVYSCKTMKELAVLKWHKGCYTI-GLAAAGSKDGKISLWDI Aurde31 ILRLHLYSGDIQGTSTRTMRHGRDNKLHLWAKSMDVNALNFCRFSLLVALPNLIDSSLPSGDRLHAGIIMSL-HLYLV-TAFESGTVALLESVMGMAAAITVSADHLIAAVSIRPDGRICAVAGWDGKI-RLYSTKSFKSLGTLVYHRGCSCV-AFPAAGSKDSRVTVWNL Batde5 TLRGHLASGDSAGWDLVYRRQGRDNTVHIWSYSFPTNSLNFCRFAMLFAIPNLTDSNYTTRSYMIRGIVMCM-QFFLLAAGYESGHIIIIEPVMSLDIVVSVAADNQLSDVRIVFDGSEIITAGWDGALRRFKPSKKLKCTNVVQAFKSIKCM----AIGSKDGRICLS-- Botbo1 VLRTHIYSGDASGTSTRTFRHGRDNKVHIWSKSLDVNALNYCRFSLFLAVPNLVESSLSSLDRIHAGILMSS-HLFLL-CAYEDGSVTLQESVMGLSVSITVSADHILAAVTMRDDGRVCAVAGWDGKI-RLYSTKTFKPLGILVFHKTCQAV-IFAISGEKNGRVAIWEL Botci1 ------------------MR-----------HMLDVNTMNFCAFAMLLAVPNTLTSEVPTLHRLHNGMIMCL-SLFVL-SGYEDGSVSVIQPILSLSLDLTSGADDRIQSIEMRNDGKIAVTAGWDGRA-RVYGVAKMRELAVLKWHKGCFAI-AVAAVGGKDGKVSLWDV Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ILRGLGESGDPD-WTRTTPKQGRDGFLRLWDCSIPVDTVTFCKLSVLAAVPSL-DMTLTTQQVICSGTCTSV-KLYLL-AGYEGGEVVLQEGVLSVQASFSCGIDDVVNELAIRPDGKLVATGGWDSKV-RVFSARSLKQLAVLRLHTSVHAV-AFSATGSKDERIGLWSL Catan2 VLRGHLVSGDADGWNLHTFFMGRNDGICIW-----------VRLELLIACPAADSTFGSRFSCLIRGIMTCSPAFT-------------IQPI----------KDGQL-----AYDTGKVVVWGWPQTLVEALPHDRRQC------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ILRGHLLTGDANGWSLATKRHGRDHTLRVWQHSLPVNTLNFCAFSMLVAVPGR-DDKLPDETLQIIGMVMAV-KLLLL-AGYEGGVAAASQPVLSLDASFTSSADAKLQSLQVRSDGRLIVTGGWDARV-RIYSSKTLKEVAVLKWHKGVYAV-AFAAAGAKDGKVSLWEV Coere1 VFREHLVSGDQSGWNMLLKRQGRDSKIKIWSKSLSVDSLSFCQFASIVAIESV-DSGVHNEAKHSFDSPMCL-RLILY-VGYESTILQCKEPLMAVDINYTCAADNKVSGIRYFGSCSLIAVAGWDYGV-HLYT-KSLEHIYTVRFHRALTAL-SMSAVASRDTRISLWNI Conco1 VIRSLLIIGDEEGFNLVNYRYGRGESLNIYKLEIPVECINFSNTSILIASPG---DE---------GQVTTM-KLVLL-VGFEQGSIAMEEPVTKIALLYSVSAGSKINDINYSNSPTLIITGGWDNSV-KLFT-KSLKYLTNLEFHKSITSA-IITIIGSQDSDISIWEY Conpu1 ILRTHIISADASGTSTRSLRHGRDNKLYVWQLELDVNALNYCRFSVLLAVPNLVDSSLPSCVRLHAGIIMSM-HLFLL-CGYEDGGLVLVESVMSMAVSLSVSADHLIASIAIRDDGRVCAVGGWDGKI-RLYSTKSLKPLGSLGYHKSAQAL-AFFVAGGRDGRISVWAL Copci -------------------------------YSMDVNALNYCRFALLIALPNLIDSSYFVTSSYHAGIIMSI-HLYLL-C---------VETIMSMAVSLTTSADHLVSCIAVRDDGKVCAVGGWDGNI-RLFSTKSFKPLGTLKYHRGCQAL-VFAVAGGKDNRLSVWTL Croqu1 TFRPFLLTTDELGWSLEYKRQGRDHRFVLSRAECPTNALTFCKAALIIAAPSAVDEKTPQINRIHRGPVISL-SLYLLLVGYENGAVTLEEPVFSVCMGWSVSADHRIFDVKMRSDGKVMATASAGGKI-WLYAS--LAPLGLIKFKTSQGGVLAFAAAAGKGGTVVVWEV CryneH991 TLRIHLYAGDQDGLDLRVRRHGRDNVVHFYERSLPTNALNFCRFSLVMAVPSLADSEIPSFQRLHAGLVMSL-HLFLA-IAYEDGRLELNEAIMASAVDWSVSADHRLSSIAISADDKVVAVGGWDGKI-RLFSAATSKPLGTLSSHRTVHAL-AFAASGGKDGKVALWGL Crypa2 ILRGHLFTGDADGWDLTIMRHGRDNKLIVWRYLLEVNTMNFCTFACLIAVPNTLISELPSQIRIHTGMVMAL-ALTLV-IGYEDGMAIVKQPILSLDVALTSSADATIQGLSIRSDGRIFATAGWDSKV-RVYSAKTMREVAVLKWHPGCFAA-AFAAAGSKDGKVSLWDV Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ILRGHLYSGSGDGWNIEEKKQGRDGVIKIWSYRLETNSLSLGKCSS----------SLKNKQVINKGLPMSL-KLYLC-TGYENGELLINEPILSFALSISGSGDTNISEIKIRNDEKIYATAGWDKRI-RIFNFKKQTPLAILKYHTSVYSI-DFNASGSKDCKIALWDI Dmel SLRSPLLAGTIKGWDLQTNRQEKGGTITMFSRSIPGNHLGFCRSALLLFYP--CEESVTDAAAPTQGSVTCF-KPFLL-AGYESGHFLTAQDATSVDYDVGGPTDKLINGVRIRPDQKVFASAGWDGRI-RIFSWKSLRPLAVLTQHKGVMDL-AFSAAAGMDGQISLWDL Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ILRIHLYSGDTSGTSTRTLRHGRDNKLHVWIYSLDVNALNFCRFSLLIAIPNLIESSLPSCSRLHA-ILMSL-HLFLL-SAYEIGEVALAESVMAMTVSLTVSADPIIGAIALRSDGRVCVIGGWDGKI-RLFSTKSFKSLGTLSFHTSCQAV-AFAAVGSQDRRLTIWEL Fusgr1 IGSFHLYFHDREAWTLQLRRHGRDMKLIVWKHLLEVNTLNFCAFAILIAVPNTLNSDLPSQHRIHTGMAMCL-ALLLV-AAFENGYATVSQPVLSLRVYITSSADSIVQSLDIRSDGRIFATAGWDSKV-RVYSIKTMKELAVLKWHQGCYAV-AFAAAGAKDGKISLWDI Galma1 LLRSHIYSADASGTSTRSLRHGRDNKVHVWQYSMDVNALNFCRFSLLIALPNLIDSSLPLIDRVHAGIIMSM-HLYIL-MAYENGSVILVESVMAMRVSVTVSADHIIGSVAIRDDGKVCAAGGWDGKI-RLYSTKSFKPLGTLKYHKACQCV-EFAVAGGKDNRVSIWSL Ganpr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 IFRGHLISGDAEGWDMKIKRHGRDNLLKVWKKSLSVNSLNFCKFDYLIAVPSSKESTLSNQQFITSGYCMAM-KFFLL-AVYENGGLILKETALALDVSISTAGDNKIADIKIRSDSKIFATAGWDSNI-RIFSSKTMKPLAILSYHKSVYSL-AFTVGGGKDNKISLWKI Hisca1 ILRGHLVSGDAEGWNMRTKRHGRDHKLRVWRHSISVNALNFCAFALFLAVPNALNSGLPSEKRVSTGMVMAL-ELFLL-SGYEDGRVMISQPVLSLSLFLSSSADAILQSLRIRNDAKIFATAGWDGRI-RVYSCKSMRELAVLKWHHGCYAV-AFAAAGSKDGKISLWDI Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 FLRSHIYSADASGTSTRSLRHGRDNKLHVWTYSMDVNALNYCRFSLLIALPNLVDSSLPQLDRIHAGIIMSM-HLFLM-CAYEDGGVTLTETIMAMRVSLTVSADHIVGSIAIRDDGKICAIGGWDGRI-RLYSTRTFKPLGTLKYHKACQCV-EFALGGGKDNRVTVWSL Lenti61 IVRSHILSGDAVGTSTRSLRHGRDNKLHVWKYSLDVNALNFCRFGLLIAVPNLVESSLPGKQRLHAGIIMSM-HLMLL-CSYENGSVTMVESVMAMAVSLTVSADHLIASVTIKDDGRVCAVGGWDGRI-RLYSTKSFKPLGTLSYHKSCQAV-AVAVSGGQDNRVAIWSL Malgl1 IVRHHLLAGDSQGTHLSYYRHGRDNSIRIWKHDMGVNALNYCAYDMWLVTPHTLDSALPSQRRIVEPVVMSL-QTCII-AGYEDGSLRAAEAIMAICVSLSVGADYHI--TSLTPNA-------------------------------------------RRPGNACTATF Mellp23 TFRPFLLTTDELGWSLESKRQGRDHRFVLSRADSPTNTTSFCKAALILAAPSSVDEKAPQIHRIYRGAVMSV-SLCLLLVGYESGAVALDEPIFSMCIGWSVGADHKIFDVKLRSDGKVMATISAGGKI-WMYGS--LPPLGLLKLKTIRGGVLSFAAAADKGGSVIIWEV Mnele VIRGELVTGSEEGYDTQIMRQGREGGLALWKRSCSVPSTGFCRFALFLGLDEKSKVALNVVKTFQPGMCWSL-------LGYESGHIVLDEIVTTLDV-ISSSPDSTISQIRIRPDGKLFAASGWDGGL-RLYSVKKYKFLGLVEAHCTITDMITFDICSGRDCKISFWTF Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 IFRGHLATGDETGWDIWKRRHGRDNEIHFWDLSLPVNALNFCKMA-YVAVPSPTTSSVTKPERTFAGSAMSI-KLFML-VGYEDGSVTLREPVLAVDVSISCGSDNVLADGKIRSDEKVIALAGWDGRI-RLFSSKTLKPLAVLKYHRGLYCL-GFAAVGGKEQRISLWDI Mucci2 IFREHLASCDADGWKMKTRRQGRDNQIHIWKASIVYNALGFCKFS-LLCFPSRDDIALTYQCYVLQGSCMAV-ELFVL-AAYESGSTALQEPVLDLSIDISSSADNQIVALRIRPDNKIFALGGYDGRI-RLFSVKSMKPLAVLSYHKTVYSV-DFSVCASQDHRISLWSI Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ILRGHLVTGDADGWDLTIMRHGRDNKLIVWKHLLEVNTMNFCSFSYLIAVPNTLASELPSQTRRHTGMVMAV-ALFLV-AGYENGLAIVSQPILSLSVSLTSSADAVIQSIEIRSDGLIFATAGWDSKI-RVYSTKTLKEVAVLKWHQGCYAV-AFAAAGSKDGKVSLWDV Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 VLRGHLVSGDANGWDLVTKRHGRDHKLCVWKHSLPVNALNFCAFSMLFAVPNALDSGLPSERRISTGMLMAV-NLFVA-SAYEDGHVMVSQPVLSLDVAISSSADALIQGLRIRSDEKVFATAGWDSRI-RVYSGKTMKELAVLKWHKGCYSV-AFGAAGSKDGKISLWDI Phybl2 IFRGHIASGDGDGWKMKTRRQGRDDKIQVWQFHIPYDSLNFCKFSLLLAFPSNGDTPLTLRKWAIRGLCMAV-ELVLL-VGYEDGSVSMKQPVLSMAVDVSTSADNQIAAVAVRPDNKIFATAGHDGKI-RVFSCSSLRPLAILTYHRSAYCV-AFGISGGKDARISLWAI Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 LLRSHIYSGDASGTSTRTLRHGRDNKLHVWKYSMDVNALNYCRFSLLIAFPNIVDSSLPSQRRLHAGIIMSL-HLFLI-CAYEDGGVALVESIMAMAVALTVSADHLISAIAIRDDGRVCAVGGWDGKI-RLYSTRSLKPLGTLDYHKACQSL-SFAVGGGKDNRVSIWTL Polpo VLRGHLYSGSGDGWNVEEKRQGRDGTIKVWNDKIETNSISLGKCSPLVAISSDEVPSLTQREIVMRGMAMSI-KLWLC-SGFENGGLCLTEPLLSFALKVSGSGDNKISDVKIRGDGKIYATAGWDRRV-RIYNFRKHTPLAIL--------------------KVCVVDI Pucgr2 LFRPTLLTADNHGWNLDSKRQGRDHQLILNQAQTPINAINFCKASSIVALPSLISEEPPKIIKICEGSVVAV-QLYLMMIGYESGEARITEPILSLTISWSVGADRKIFDVQVRSDGKVLGIYTWGGKL-WLFDTTALRPLLVLKLPTHRSGVLAFAVASAPAGQIIAWEV Punst1 ILRIHLYSGDTSGTSTRTMRHGRDNKLHVWKYSMDVNALNYCRFSLLVALPNLVESSLPARDRLHAGIIMSM-HLFLL-LGYESGAVTLVESGTS----FTVSADHLVAAVAIRDDGRICAIAGWDGRV-RLFSTKSLKPLGTLSYHKSCQTV-HFAVSGGKDSRIAIWPL Rhior3 ILREHLASCDEEGWKLKTRRQGRDSMIHIWKKSIVYNDIGFCKIS-LLCLGSMEDVEVTRYEWIIRGACMVV-KLYIL-AGYEDGSTVLKEP------DISSSADNQIPTLSIRHDNKIMGSGGYDGRI-RLFSINTFKPLAILNFHRTVYCI-DFGIGASKDNRISLWNL Rhoto1 ILRGHIFTGDTDGWDLQSFRQGRDNMVHFFRWSIDVNAMNFCRMSVLMAVPSLTKDDVPSKARLHRGTIMAL-HLFLL-IGYESGHLALRDAVMSLAVTFTVAADHFISAVAVRSDGKLLATAGWDGEL-RLYSAKSLQPLAVLSHHRSLQAL-VFAATGGQEAKVSLWEV Rozal11 --------------------QGRDSYIHQWLRSVSVQNFSFCRMEIIGLLP---EENLTSNERVDVGSLMCL----LA-SGHESGSISVYNFLLLMSIAVTTSVDNILNHVCVNSDLKMMTVSSWDCSR--------LRLKKTLSLHRSIYCSIFFQAVSSKDGLISLWDL Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro SLLGFLVTGCEDGWDLKERKWGRDQLLQVWNVKKELGGINFCRMASVLALSDADNET---------GQLMAV-ALFAL-TAHESGQLRLPTPVPVVSVALCGNAESKLNAISVRAPARLFAAACSDNKV-RVYSRKG-RALAVLDQHVSALCV-AHSASGGKDCVVHLWSL Schco3 ILRAHVYSGDASGTSTRTLRHGRDNKLHAWPYSMDVNALNYCRFSLLIAVPNLVDSSIPSRDRLYAGIIMSL-HLFLL-SAYEHGGVILAESIMAMAVTLTVSADHLIACIATRDDGRVCAVGGWDGGI-RLYSTKTLKPLGTLRYHKSVQAL-AFAVAGGKDNRLTIWAL Schpo1 VLRGHLYSGDEAGWCLTSMRHGRDCRLVTWKSNIVVNSLTFCPFS-IVVLCNTLNFEDESLYHPQTGSVMST-SVTLA-AGYESGHVVQSQPVLSVEYAFSTGADDCIQNIRIRSDNKILATAGWDGRG-RVYSCQTLAPLAVLKYHSGINSL-AFHALASKDTRISLWKL Sorma ILRGHLVTGDADGWDLTIMRHGRDNKLIVWKHLLEVNTMNFCSFSYLIAVPNTLASELPSQTRRHTGMVMAV-ALFLV-AGYENGLAIVSQPILSLCISLTSSADAVIQSIEIRSDGLVFATAGWDSKV-RVYSTKTLKEVAVLKWHQGCYAV-AFAAAGSKDGKVSLWDV Sphar FLRGHLASGDANGWDLDRRRQGRDESVKIWDGWITTGAIDFCRADY--------MPGTSTKREMCTGMCMSV-RLFMALAGYEDGSVHLSEPVMTLDIATTGSVDNIANDILIRQDKKIVVTGGWDGNV-RIFSYRKGTPLCVLSRHRSVQTLASYNAAGSKDRNISLWSV Spipu1 VLRAHLASGDQEGWSVLTRRHGRDDQLHIWSFTLLVNSLNFCGVSLLLALPGLGENALSTKTYTLQGLCMCL-KFFLA-AGYESGTIIIEEPVLSLDVLFSGGAETKIAVVRIRPDGKIVATGGWDSKI-RIYNAKKFKPLAILRGHRGVSCL-AFSAAGSKDGNVTLWQI Sporo1 ILRGHLFSGDSSGWNLGTYRHARDNKLHLFDLDLDVNALNFCRLSLLIAVTSLTKDDVPSKDRLHRGSVMAV-HLLLL-IGYESGQLALRDAVMSIEVSYTVGADHLLSTIRSRSSSEILAVGGWNGEV-RVYSGKTLEPLACLDHHRSVQAL-DFAATGGIDTKICLWKI Stehi1 LIRAHIYSGDSAGTSTRSLRHARDNKLHVWKYSLDVNALNYCRFSLLIAVPNLVESSLPSKQRLHAGIIMSM-HLLLL-ASYESGSVMMVESVMAMALSLSVSADPIIGSVAIRGDARVCAIGGWDGKI-RLYSTKSFKPLGTLRYHKSVQAL-AWAISGGKDGRVAIWEL Tapde11 ----HLLSGDADG----------DNKIHMWECSLDVNSLNFCQASFLLAVPGLIGNDLPSAHRLATGNVMAV-DLQLC-VGYENGAVAIRDAVLSVTLNYSCGIDSRLQSMRMRSDQKLLGTAGWDSYA-RIYTTSKLKQVAVLGFHKAINAI-DFQALGSKDAKISLWKL Thetr -------------------R-----------WRVDAQTLNFCGVAAVVLVASGDDPGAEMASARCEGMCMAV-RLV-V-AGYESGALAVGDPVMALDVVGSATAEAVASSVAIRADGKLVALGGWEGSL-SVHSAKKLKPLAVLEYHARVSAL-GF-VSGSPDGRIAVWDL Treme1 -------------------------------------------------------------------MSLHL-HLFLA-LGYEDGRIEV---VMAMVVDFTVSADHLLSSLSISPQGSVIAVGGWDGKI-RLYSTSTFKPLGILNYHRTVNVL-AFAVSGGKDHRVALWSL Trire2 ILRGHLATGDAEGWDLTIMRHGRDHKLIVWRHLLEVNTMNFCSFAALIAVPNTLASELPSQTRIHTGMAMSL-SLFLV-AAFENGFVSVTQPILSIDVHFTSAADALIQSLKVRSDGKLLATAGWDSKI-RVYSTKTLKELAVLNWHKGAYAV-AFAAAGAKDGKVSLWDI Umbra1 IFRGHFCSGDLEGWDVETRRQGRDNRIHTWKSTLLYNSVTFCKVALLIAVPSHMDPGLFSQWRQVAAMCLSM---FLL-AGYESGRLVL--TAPVLSASFSGCSDGLIEQICIRSDAKIIATAGWDSRI-RIFSAKTLKPLAVLTYHRSVYSV-AFCVGASKDHRISLWEI Ustma22 ILRHHLAVGDECGVDLAVLRHARDNTLKLWRRDIGVNALNFAKCSMSLAVPNALDAALTTGVRTHEPIVMSL-HLLLV-AGYEDGCVKKSESVMALAVS-SVGADDRLSSTAIAPDALTFAVGAWDGSI-TVYSTADLSRLGSLDYHKTVECL-AFAAAGGRDGKVSLWTY Walse1 IIRSHILSADDDGTSTKTMRHGRDNLVKLWEDRFHVNALNFCNVSLWLAAPHLTDSSIPSKERIFRGLCMSL-KLYLL-AAYEDGSVVLNEAVMGLCTTFTVSVDRCISSISVRKDSKILAVGCWNGSV-ELYSAKSMKLVGVLDLHRSVSSL-AFSLTGARDDRVAIYQ- Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3024.fasta_al_trimmed; alignment length = 37] Allma1 MTRGDERERARLRNLKKQKKRQESDAEIMAEAKAAAA Ashgo11 MARGNQRELARQKNLKKQKKRMESDAEILERKERERL Aspfu1 MTRGNQRDRDREKALKAKARAKENNAAIMARKAAEAA Aurde31 MTRGNQRDTDRAKAQKKAQKRKEADAQALAEKAAT-T Batde5 MTRGNQRDLAREKSAKKTAKRKEHDAAALKKAAAEQS Botbo1 MTRGNQREQDRLKAQKKAAKRKQADADAIEAAAAAAA Botci1 ------------------------------------- Caeel ------------------------------------- Canalb1 MARGNQRELARAKNLKKQQKRMETDAEKMARKAAEAL Cangl MARGNQRELARQKNLKKQQKRMESDAEILARKEAERL Capow ------------------------------------- Catan2 IPGGNQRELARAKNLKKQQKRMESDAEIMAKKAAAAA Cioin MTRGNQRELARAKNLKKQQKRMERDADIMASKEAAAS CocheC53 MARGNQRDKAREKNLKEQARTKENVAAIMAKK-AEAA Coere1 MTRGNQREQARQRNQKKQDKRRENDAEIMKEA----- Conco1 MTRGNQRDKDRERAQKRAANKMESDAEIMDAKNAVTA Conpu1 MTRGNQRDTDRAKAQKKAAKRREADAELLEERTGGEA Copci --------MDRLRAQKRAAKRKEADAEALEERAAAAA Croqu1 MTRGNQRENDRAKAAKKLAKRKEEDAQKMAEKEAKAA CryneH991 ------------------------------------- Crypa2 MARGNQRDLARAKNLKKQARDKEAVAALMEKKAAEAA Debha1 MARGNQRDLARAKNMKKQQKRMESDADKM-------- Dekbr2 ------------------------------------- Dicdi ------------------------------------- Dmel MTRGNQRDLARQKNQKKQAQRKARDAELM--KEEAAA Enthi ------------------------------------- Falba MTRGNQRDIDRERARKRAAQARENNSEIMERKREEAA Fomme1 MTRGNQREKDRERAAKKAAARKEADADALQKRQQAAA Fusgr1 ------------------------------------- Galma1 KNRGNQRDQDRLKAQKKAAKRKEADAEVLTSGLSSTE Ganpr1 MTRGDQRERDRAKNLKKQGARKERDAERMAAAAAGGS Gloin1 MARGNQREKAREKNLKKQSKRAESDAEIMLES----- Hisca1 MARGNQREKAREKTQKEMARTKEAQAAIMAKKAAEAS Klula1 MARGNQRELARQKNLKKQQKRMESDAEILERKEKERL Lacbi2 MTRGNQREQDRLKAQKKAVKRKEADAEILEEKAVAEG Lenti61 --------MDRAKAQKKAAQRREKDAAALQE-AAAAA Malgl1 ------------------------------------- Mellp23 MTRGNQRENDRAKAAKKLAKRKEDDAQKMAEKEAK-A Mnele ------------------------------------- Monbr ------------------------------------- Morel2 MTRGNQRDQDRLKAQKKLAKRAESDAEIMAAKAAGGG Mucci2 MARGNQREQARAKNLKKKEQKKESDAAIMAKKQAEAA Mydma ------------------------------------- Neucr2 MSRGNQREKAREANLKKQARDKEAVAALMAKRAAEAA Orpsp11 ------------------------------------- Pench1 MTRGNQRDNDRAKALKKAGRSKEDAAAIMEKKAAESA Phybl2 MARGNQREQARAKNQKKMAQKKESDAAIMAKKEQESA Picst3 MARGNQRDLARAKNLKKQQKRMESDAEKMW------- Plicr1 MTRGNQREQDRAKAQKKAAKRKEADAEILEEKAAADA Polpo ------------------------------------- Pucgr2 MTRGNQRENDRAKAAKKLARRREEDAQKMALK----G Punst1 MTRGNQRELAREKNAKK-QKRKEADAAALEARAAA-A Rhior3 MTRGNQREQARLKNLKKKEQKKESDAAIMAKKQAEAA Rhoto1 MARGNQRDKAREKAQKKAAARQEADAAIMAKKAADGA Rozal11 ------------------------------------- Sacce1 MARGNQRDLARQKNLKKQKKRMESDAEILARREAEKL Salro MARGNQRELARKKNMKKQQQRRERDAQRLAKKAAMKA Schco3 MTRGNQREQDRLKAQKKAAKRKESDAEILEERAAAAA Schpo1 MSRGNQRDVDRARNLKKSQKRLEAQAEIMERKAAEAN Sorma ------------------------------------- Sphar ------------------------------------- Spipu1 ------------------------------------- Sporo1 MARGNQRDLAREKAQKKAAARQEGDADIMAKKAAEAA Stehi1 MTRGNQREADRAKAQKKAAKRKEQDAEILE--AAAAA Tapde11 MARGNQRDKAREKNLKKKEREQESNAEVCAPDNATKT Thetr ------------------------------------- Treme1 ------------------------------------- Trire2 MARGNQRDLARAKNLKKDAKASLSNAEIMEKRREQEE Umbra1 MTRGNQREQDRLKAQKKAGNKQESDADIMAKKAADSG Ustma22 MTRGNQRELARAKNQKKQAKRKEADAEALAAKAAEAA Walse1 MSRGNQRDKDRERAQKKAANKREADAQALAKATVTSS Zygro1 ------------------------------------- [Cluster3026.fasta_al_trimmed; alignment length = 364] Allma1 ISLSVEETNALRAKLGLKHDKK-ANFAAAAAEQKKQQEIADVRRRLEKSQNRRKLQERLKGATLGTAWI----QRQKEFDGLELKVTHALD-DLEGDEMVLTLKDKGVLDELENATLRDVEKAQEAVELRGK-KKTILAQYDEARYTLLSLNYNKSASEVTIKKSKRKKAKIRSKNFVDDEDLQSVLAAARLR-DEIAE-DLASLVFDETSEFVRGLALNK-GLGAAMELFRKRGALEDASIRERESEAQ-----ELENFTTK-------KRTE-RLKDYKPNV-NL-EYYDAQGRQLSTKEAYKE-LSHKFHGRT--SGKNKQEKVQRKEDERRRMMQMTSGDASSLASAMLERQKLLTVGNR Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 -ALSIEQNNKIRVALGLKSRQALANWKKLQEEAEAKRRREAKNAAIKKARDAAQRARILEGPTLGETWLLQAKKRQKELEERELKVGHEIG-EFAGEEHVLTLKDTTIDDELEDVNLREKEKVAERLELKKR-K--ILAQYDEKRFTLVSLDLGADVSEIKIKKPKKKKVKATRQSFVDDDDLQASLTRQRRAAEDIAR-QLR-LVIDETSEFVSNLTLDQ-GLGATLNMLKQRGLVK--PEHNALLRARLHEKIRQQRERDRAR-WENKQRDQEVFNKYKPDV-QL-KYVDEFGRLMNQKEAFKH-LSHQFHGKG--SGKMKTEKRLKKIEEEKKREAMSALDSSGMNNAMGATARKRQAGVR Aurde31 ESISLEETNKIRISLGLKSADALANYTRQRERERREQESRRIFESIAKVKNRRELNAGLKGRTLADKWIKRSKKQEKELENMDLKVAHDLD-ELEGQERILTLKDSRILDELMNVEMADHERTKKRQDMKIK-KRAVLAKYDETGFRLLSIDYAKREGDKGFKKPKTKKKRATRVNFVDDDDLQSALARARQVKEEIAA-QIAELVFDETSEFVRAVTIGA-GLAGALSVLRRQGILATPSEREKVQVQRLAEQREEERSRSRRE-HENRMREQEHFKNYKPDV-NI-VYYDEFGRALSMKEAWKA-LSHRFHGKM--PGRMKQEKRLKKIAEEKKREAMASGDTPNMNRAFQARQEKLSVGNR Batde5 VSLSVEETNKLRTLLGLKSKNAQANFQRHKDDAIKKKERMDLAEKINREKELAHRNKKLAGKGLGEAWVLKTKAKSVELTEMDLRVGHAID-DLETGETTLILKDSTIMDELVSVSLAEHERTKKNLDNKKK-RKDILHQYNDTSFTLVSLDYEKKDELVSFKKPKSKSSKRASSNFVDDDDLQLALAGARRRAESIAT-QVTTLVMSDTSEFVQTLLVSS-GIAATMALLNQKGLIQPLTAREAKLQEHLTQRKDSKRL---RD-RERAERDARRFENYSPDV-NI-KYHDDHGRELSTKEAWNQ-LAYKFYGIM--PGKLKTEKRLKKLQEELKMKQMSSIDTPGFSSALQEKTRRLSVGNH Botbo1 SSISLEETNKIRISLGLKNKEKEANFAKRKQAEAREKEQSEIVARIQKNKNRRELNRRLVGTTLGDKWVKKAKKKEKDIEKMDLKVSHDFE-GLEGEDRILTLKDSRILDELQNIDMAEEEQDKKRFENKIK-KRAILAKYDETGFRLLSIDYAKKEGDVGFKKPKTKKKRSSRRNFVDDDELQAALARTRRTKEEIAR-RVAELTFDETSEFVRAITFSS-GMAGTLKILQQQGILKTVSERDRNQKAHLADHRELDRLRSRRE-YENRQREQEEFKNYKPDI-NI-KYHDEFGREMTDKEAWKA-LSHRFHGKG--SGRMKTEKRLKKIAEEKKKEAMASGDTPSMNRAFQIRQEKLSVGNR Botci1 -AISIEETNRIRASLGMKSRQAEGNYRKIQEAEETKRKREAKAEAIKKARDTAKRFAKLEGKGLGEAWLMKQKKRQKELAEAEVRVGHELD-TFEGEDQVLTLKDTTIDDELENLDLREREKLSDKLELKKK-KRKILAQYDEKRFTLFSLDILKDISDIKVRKPKKKKAKSTRQSFVDDDDLQALLATQRRNAEEFAQ-RLRDLVIDETSEFVANLTLER-GLGSTLKLLRERGILK--TDVATIFREKLAEKQKAQRERDRAR-QQNTMRDQEHFNKYKPNV-EL-KYVDEHGRNMSQKEAFKH-LSHQFHGKG--SGKQKTEKLLKKIEDEKRREAQSSLDGSGMTGAAAQQLKKRQAGVR Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ISLSLEETNKLRIKAGLSSSDST-NYEDYERERLQNLKNNQLIERINNAKFNSNKRKFTNETIIDNDWLNNLGESTEKTTIVKTIIGHTTK-ELLGNNEILTLKDTDLISILMNQDLSNKAKLKRNLAERKEAENDIDGLLTNSTIDLEDLDNVTSNVPIKMKKIKKKK-DNNKKDIDDIEQLSNSISNLRTKKEQLAE-EISA-VYNDTIGFLNNLKFSG-GLAETLKFLKSRNILDPESELAREEAIKLLKMKELSKDKSYKL-LDTRLKQKGMVQNYNPKV-EL-TYKDELGNVLNTKQAYKQ-LSHKYHGTGLDKNKKKQEQLKKKQQQQRGSKSTNISTTS------------N----- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow SVLSIEETNAQRAALGLKAAPALSKFLEEQAQIQKEKDAKTLEERLAAHREARRIEDSKATKTLGASWVTQSRKAQDAFDELDLKVAHDVE-DFEGS-TVLVLQDTGVLDVLENVNMADHERAKQNAIRRANSKTGLLSHYDETVL--VSLDSDTPEEMISFKKPSKDKHKKRRTFVADDEELARALERTRRLKEDSTE-----LVFSATSEFVKNISLVN-GVGAALAFMARRGMIENESETDRQRDKGMDQEEEIRRQREARD-VRDSRSDRDPFSM--PEF-TL-DYVDENGRTMTTKEAFNH-LSYKFHGIQ--PGKNKQEKRQRKLEEEVLIKQMAAGDTPHTRETTYKKMQEISGG-- Catan2 ISLSVEETNALRAKLGLKTDTQ-ANFALHQAAQQSKRDAADVAKRIEKSRNRFKLRAKLAGATLADAWA----KRQKQYEDEELAVAHDLNQEMEGAELVLTLKDKDVLDELENSALRDKDRLRQTLENRSR-KRSVLAHYDEGKYVLMSLDYEKSADEITIKKSKKKKSKLRSR-FVDDDDLQSVLAAARRKADQVAR-DLAELVFDETSEFARVLALDTMGLGSALEFFRLRGALDAPDQREHEYKAR-----DATNASAP-------RRAE-RLKDYKPDV-RI-EYHDAQGRQLSTKGAFKE-LSHKFHGRR--PGKNKMEKMMRKEEEKRRQMNMASGDKAELASAMMERQKLLTEGNR Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 --LSIDEANKIRLSMGLPTRQAAANWKKLEQERLAKIRREERAAAIKKERERASRFTKLEGKGLADAWLKSSKKRQKELEEREVKVGHELD-EFDDEDQILVLKDTAVDDELEAVALREKERLQERLDSKKR-KKSILAQYDEKAFTLISLDILKDVSEVKMKKPKKKKKKSKRESFIDDDDLQANLAAQRQKAEDLAR-QLRELVIDETTEFVQNLTVDQ-GLGATLALLKQRGLVT--EEKNALYRERMADKAKIVRERERAR-KNNTSADMELFNKYTPNI-EL-KYVDEHGRQMNQKEAFKQ-LSHQFHGKG--SGNTKTKKHLEKVAAEKKKMAESSLDSSGLGNAFDDQAKKTRAGPR Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRDYKPEV-KL-EYVDETGRQLSTKEAYKQ-LSHAFHGHY--SGKNKIDKVMKKRDQERRQLELTASDSTRHGQALENSHKKFSSSDT Conco1 VSLSIEETNKLRIAAGLKTSEELANFKKLQEEQAQKQQEEDIKDRIEKSKNRRERFAKLEGKGLGESFAKRLEKLKT------LNVRHDLN-DFEGQEVILTLADKDVLDQLVNVMLEEREKTQRNLDSKKG-KRSILSKYDEKGFKLISLNEISEEAEVTFKKLKKKKSKSKTKNYVDDDDLQQSLARTRSKAESLAE-KVAKLVLSATSEFVNNLLVSK-GLGATLDFLTKRGLYQKPTKRDELSKKRALEQKELDDYDERRD-ASRDRRSKDMMKDYQPSF-KL-EYKDAAGNVLNSKEAYRQ-LSHRFHGKS--SGLKKTEKRLKQQEDQKKLESMSISGAQGLAEALAKKQKELK-DNK Conpu1 ESISLEETNKIRISLGLKDQDKQANYAKRREAAAKESQTKKIVDRIAKVRNKRELNASLTGVTLGDKWIKKAKKKEKELENMDLKVNHGLD-DLEGAEHILTLKDSRILDELQNVELAEAERTRKNNELKIK-RRSVLAKYDESGFRLLSIDYDKKEGDVGFKKPKTKKKRSSRRNFVDDDDLQAALARSRRAKEEIAR-RVLELTFDDTSEFVRSITFGS-GMASTLNILRQQGILSTPAERERVQRQRLADYRELERLQARRE-YENRMREQDLFKNYKPDV-NI-VYYDEFGRTLTPKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIAEEKKQEAMASGDTPSMNKAFQMRQEKLSVGNR Copci QSISLEETNKIRISLGLKDKEKTANYAKLREKEAKEREAKQIQDRIAKVRNRRELNASLKGATLGDKWLKRSKKKEKELEEMDLKVSHDFD-ELEGEDRILTLKDS---DELQNIEMAEEERRKKNQELRIK-KRSILAKYDESEFRLLSIDYAKQEGDVGFKKPKTKKKRSSRRNFVDDDDLQAALARSRKAKEELAK-KIAELVFDETSEFVQAVTFNS-GMAATLNILRQQGILAAPTARERTQKQRLAEQRELEKY--KRE-YDNRLREVEDFNNYKPDV-NI-AYYDEHGRELSVKEAWKA-LSHKFHGKG--PGKMKTEKKLKKIAEEKKKLAMASGDTPSMNKAFQQRQEKLSVGNR Croqu1 ESLSIEETNKIRISLGLKTSEARANYSRRRAEESEAKKAGEVQERVIKAKNKRELSARLAGRGLADTWVKRQKKQSKEIAEQELKVAHELE-DFQGDEVVLTLKDNRILDELENVNMTEDTRTKEALELKRK-GTEVLSKYNEKTFRLMSLDYTKQEGDPGFKKPRKSKKKDKSSIMIDDEEIQAAMSRMRREADESGP--MENIVIDDTSEFIRTVYVRG-GMASTLSLLKAQGLIKPLTEKERLYKEKLIEQREMEKERTKRE-YENRMRESEAYRNYKPDV-EI-KYNDEFGRELTQKEAWKA-LSHKFHGKG--SGKAKTEKRIKKIEEEKKLAAMASGDTPGTNEAFRKRQEKLSVGNK CryneH991 ESLTDEEAIQLRLQLGLSDTDAIANYAQRKAEMKREKEEKELKERIDKARNKSALNAKLKGTTLSASWIKRQKKREKDKEEQDLKVGHGVE-EFEGEDVILTLKDTGVLDELQNVNLVEDAAIKAARERKRKAQADVLGKYDEEGFRLLHLDYTKKEGEAGFKKPKKKKKRSTRRNLVDDEDLQAALSRARRANEDVAA-QIAQITFDETSEFARNVTVGQ-GVAGVLALLRHQGALKARTERERVQKQKLADYRELERIQARRE-WENRMREQDIYKNYKPDV-NI-VYHDEFGRQMTPKEAWKS-LSHKFHGKT--SGRMKTEKRLKKIAEERKQLTMNSSDTPGMTDAFSRRQQMLSVGNK Crypa2 -ANTIEELNKVRKAMGLKTREAAANYRRVLEAEKTKREREARLAAIKKEREKAQRFATLKGQGLGDAWLKSMKKKQKEAEAAAVKVGHDMT-TFDGDDQILTLKDNTVLDELENLNLREQEKLNEKLDLKKK-RRSILAQYDEKAFTLLDVDIMKDVSEIKVKKPKKKKAKSTRQAFVDDDDLQNSLALQRRQAQDIAK-QLKALVVDETTEFLSAIYVAQ-GLGATLALLKERNIIDA-TQKNEHFRQRLAEQAKRQRERDRAR-KQNADREFNLLKKYKFNV-EL-KYVDDMGRHLNQKEAFKE-LSHQFHGKT--SGKGKTDKKLSKVEQEKRRMATSIFDASGMSNATAQQTKKKEAGVR Debha1 ISLSIEETNKLRVSIGLESREEN-NFQRHQSEIRDKERDDEIKQRIDTAKARNLTRKRATGKTLLSDWLKKLGQPKGTDESIELRVGHNSK-ELLKNNEILTLKDIDVL--LTNEALVRDARFKKELQDKVGAE-------DEATIKLSDVEASEPKKPIKMKKLKKK-TQNSRNLLAD-DELNSVLSMKRNLKEQIAQ-EVKLIVYNDTSDFLNSLSFNG-GLASTLKFLQSRQILQKQTAKQQREALKLLKLKYLEADKSYSH-LDQVLKEKPSINEYNPDV-KL-SYRDESGTELNTKEAFKY-LSHKFHGVG--PGKGKIDKKLKKIQQQRDKNSSS----------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ESLSLEETNRLRAQLGF-PASGPS-------------EISRMRERIESQRATRKASTVGPTKSLGESWISKHRQRMREDDLVQLRVAHDLG-NLTGREYILTFADKHVLDELESLDLRENEKIAKRKEAIERSRGNILDKYDDKAFYFISLKAVKAEEVVRFKKTARSARRAPRVNFVDDDDLQASLARSRRKKESIQAVRATAVTLSFASEFARQVVVAA-GIASALRFVQNKGHLEAPMERQSVWAAQL-ERRSNQAARNRIQ-AERARIEHALYRNYDPTV-NI-RYTDAFGREMTPREAFKE-LSHKFHGHT--SSKNKAEKHLRKVRQEISTDSRTGAASENLSVATGKRRPR------ Fomme1 ESISLEETNKIRISLGLKNKEKEANYAKKREEEEKERDKKRLQDKIAKVKNKRELNASLKGATLGDKWIKKAKKREKELENMDLKVAHDFE-ELEGEDRILTLKDSRILDELQNVEMAEIERVKKSNELKMK-KRSILAKYDETGFRLLSIDYAKQEGDVGFKKPKTKKKRPSRRNFVDDDELQASLARARRAKEEIAK-KLTELVFDDTSEFVRSVTYGA-GLASTLKSLRQQGILAAPTERERVQKQRLADYRELERVKAKRE-YENRLREQDLFNDYKPDV-NI-VYHDEFGRELTPKEAWKA-LSHRFHGKG--SGKMKTEKRLKKIAEEKKKEAMISGDTPSMNRAFQMRQEKLSVGNR Fusgr1 -AATIEETNRIRISLGMKSRQAQANYNKVMEAEKAKKKREEKAAAVRKAREQAQRNAVLEGKGFGEDWLIGQKKRQKELATAEIKVGHDTA-GFDGDEQILTLKDTTIDDELENLDMREAEKLADRLDTKKK-KRGILSHYDEKKFTLVSLDDIIDPSQIKVKKPKKKKKKGTRQTFVDDDDLQATLAIQRKNAEDIAK-LLK-LVLGEVSEFVAGLAVGG-GMGATLALLRERGLVK--EEEYSSLRNRLTKKRRRQRERDRAR-HQNNWRDQELYATYKPNV-NL-KYADDEGRALDTKEAFKH-LSHQFHGKG--SGKGKTEKRLKKIEDEKRRESQSMFDASGMSLAAQQQLKKKEAGVR Galma1 ESISLEETNKIRISLGLKDKDQQANYAKLREKEARDRDAKKIQDKIAKVRNRRELHASLKGATLGDKWIKRNKKKEKEFENRDLKVSHDFD-EMEGEARILTLKDSRILDELQNVEMAEQERLKERIELKIK-KRSILAKYDESEFRLLTIDYAKQEGEIGFKKPKTKKKRPSRRNFVDDDELQAALARSRKAKEELAK-KIAELTFDETSEFVQVVTFST-GMASTLNILRQQGILAQPSEREKIQKQRLADQRDLERMQSRRE-YENRVREQDAFKNYKPDVTNVSVYYDEFGRALSTKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIAEEKKKEAMVSGDTPSMNRAFQKRQEKLSVGNR Ganpr1 IALSIDETNKLRISLGLKDADAEANYTEYRSKEKAQLERTAALDRIARSRNKRLLNAKLAGATLASAWVKRSRVRQHEQEEMDVRVGHRAE-DLEAGEAILVLKDSTIEDELVSNIMTEKERLARKADLAKK-KRGILSQYDEDSFVIEDLQYGKAQTEATFKKTKKKSKDRKARNFVDDEDLQAALARQRRLAEDIAR-MIKRLVLSDTTEFVRNLLVGS-GLGAALTYLNSRGMLEKPTERENLLRKRAEDQKDLWRKEARRA-REEAMIERDKFKDYKPVV-NI-EYTNEFGIKMDEKEAFKY-LSHRFHGKG--SGKQKIEKRLLKIQDKLKEEA-ASSSAPGAVQKLQEATKRLQVGNR Gloin1 -----------------------------------------------------------------------------------MQVAHDIT-DFDGEERILVLKDSSILDQLVSVQLEEQQKLKKNLENKKK-KKNFLSHYDEMGFKLISLSYDKEESEITFKKPKTKKKKVRKKSFVDDDDLQQALARARKMAEEIAR-ILTELVISDTSEFVRSLLVSS-GMAATLALLQQKGFSIKPNEKERIQRERLAEQRERQNEREK---SESSYRDRARFKDYKPDI-NL-EYVDEFGNQLTPKEAFRQ-LSHKFHGKS--SGKAKTEKRLKKLEEERKLKAMSSIDTPNMATALQERQKALSVGNR Hisca1 -ALSIEQNNKIRVALGLKSRQAQGNWKKYQDEAEARKKRQEKLDAIKRAREKAQKLVKLEGKGLGETWLKQQKKRQRELAEREVRVGHELG-DFAGGDQILTLKDTTIDDELENIDLRDRERLNERLALKKK-KGSILAQYDEKRFTLVNLDIMPEATDIKIKKPKKKKTKSTRRSFVDDEDLQASLAAQRRTAEDIAR-QLRELVIDETSEFVANLTLDK-GLGATLAMLKQRGLVK--EELNTLHRERLQEKQRLQRERDRAR-QENKQRDQEIFNRYKPDV-QL-KYVDDFGRLMDQKEAFKH-LSHQFHGKG--SGKMKTEKHLKKIEEEKKREAMSTLDSSGMNNAMGATARRRQAGVR Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ESISLEETNKIRISLGLKDKDKQANYAKQRDREAKDRQAKTIQDRITKVRNRRELNASLKGATLGDKWIKRSKKKEKEIDNRDLKVSHDFD-GMEGEAHILTLKDSRILDELQNVEMAEEERRQKIKELKIK-KRSVLAKYDETDFRLLTIDYAKQEGDFGFKKPKTKKKRPSRRNFVDDDELQAALARSRKAKEELAR-KITELTFDDTSEFVRAVTFST-GMASTLSILRQQGIIAQPSQRERRQLERVADQREIDRLQSRRE-YENRLREQEAFKDYKPDV-NI-VYYDEFGRALTPKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIAEEKKKEAMASGDTPSMNKAFQQRQEKLSVGNR Lenti61 ESISLEETNKIRISLGLRDTEKQANYAKQREREAKDRETKAIQDRIAKVRNKRELNAKLKGTTLGDKWIKRSKKKEKELEAMDLKVSHDFE-GMEGEARILTLKDSRILDELQNIDLAEREKEKKNQEMKIK-RRAVLSKYDDTGFRLLSIDYAKQPGDIGFKKPKTKKKRPSRRNFVDDDELQAALARSRRAKEEIAK-QIAELTIDDTSEFVRAITFGQ-GMAATLNILRQQGVLAKPSERERVQLQRLADYRELERAKMRRE-YENRVREQEAYKNYKPDV-NI-VYYDEFGRELTPKEAWKA-LSHKFHGKG--SGKAKTEKRLKKIAEERKKEAMASGDTPSMNQAFQIRQEKLSVGNR Malgl1 ESLSLEEANRVRISLGLKDERDHNNGDHDRVDNATSSDKEAIRERVVRAQARRDVARRLRGPTLGEDWIRHARRQAQQAEDEQLRVAHDLD-EFGSDERVLTLRDANVLDELMEHSAETYAKARTDQRDRER-HTGVLDKYDHLGFRLTSLDYVK---EVSFKK-KSKKRAPRVKALIDDDELAASLARTRRMHEMVAR-NLAALTFDETTEFVQNIMASG-SVASVVQFLKSQGTLEHVPEHEKTQLKYLRERRESDDQDARRE---------ERFKDYKPDV-KI-EYHDEYGRTLSTKEAWKQ-LSHTFHGNA--PGHKAQEKRLRRIAEEQRRERMLAGDTSAMTRAFQERSERLSVGQH Mellp23 ESLSIEETNKIRVSLGLKTSEEKGNYKRRKEEESEAKKTKEIQERILRAKNKRELSSKLKGRGLGEKWVKKQKKQSKEIAEQELKVAHQVD-EFQGDEVVLTLKDNRILDELENVNMKEAARDQELLSLKKK-GNQILSKYNEKSFRLMSLEYTKQEGETGFKKIKKTKKKEKSSSMIDDEEIQAAMSRMRREAEELEPTSMEDLVIDDTSEFIRTIYVRG-GMASTLSLLKSQGLIKPLTEKERLYKEKLIEQRELEKERTKRE-YENRMRESEAYKNYKPDV-EI-KYNDEFGRELTQKEAWKA-LSHKFHGKG--SGKAKTEKRIKKIEEEKKLAAMASGDTPGTNEAFRKRQEKLSVGNK Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ISASIEETNRIRLSLGLKSSAQIANMKRHREDEAKKAHEDKVKSRIAKSKNKLELNKTMSGKGLGEKWTMKSRKKEKELQELDLRVGHDMS-DFEGEERILTLKDSTILDELINIQMTEQQRLEKNLENKKK-KKNLLSQYDEDGFVIIALTYNKDEAEITFKKSKKKKSRSR-KNFVDDEDLQASLAKARRLAEQIAK-NLAELVISDVSEFVSNLLVSR-GLGSTLALLKQKGAFEMGNERSKIQSERLADAREMAQAKARRE-YENQRREQARMKNYQPDI-KL-EYIDDSGNRLNTKEAFRQ-LSHAFHGKT--SGKMKTEKRMKKLEDEKRLMSMSSTDTPGMASAFQERQKALAVGNR Mucci2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma ESLSIEETNKLRAKLGLKSSSTVESYEDREDVHKPAGSSEKIRDKMEAIREKRKINQKLKVRGIADAWVAKSRMLEKMLEELDLKVEHKGK-AFDG-EVVLTLKDKGILDVLMNINIQEEEKAKKNVYNRTH-KKGVLDKYDDESFRLVSLESDAEEEMIKFKKPKTKVKVVRKRPIIDDDELQLALERSRRSKERMAT-IIRKIILDSTSEFCRTLLPS--GMASTLRLANMKGYLKS--GNEKVRKFDLPETKDIEKLRDERY-DPYAFKEK-----YKPNV-KL-EYVDNKGRELSQKEAFRL-LSHKFHGKG--SGKLKTEKRANKIKEEKKLQLMSSIDTPNTAAMFKEKQKALSGGGK Neucr2 -AASIEELNKVRRAMGMKTREAASNYKKALEAEAAKKKREERAAAIKKAREMAQRNAILDGKGIADAWLKNQKKRQKEKEAAAVKVAHDID-TFESGDQVLTLKDTGVLDELENIELREREKLNERLDLKKK-KRTILSQYDEKAFTLVDLDMLDDASEVKVKKP-KKKTKSTRRDFVDDDDLQQSLARQRSAAEELAK-QLREIVIDEISEFVDALLVAQ-GMAATFALLKDRRLIDA-EELVKNFRESKAELARIQRERDRQR-QQNTIREQQLFREYKPTV-EL-KYVGEDGRQLGQKEAFKE-LSHQFHGKG--SGKGKTDKMLKKQEAKKKQMAQSFLDASGMSTAASHQGKKKEAGVR Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -ALSIEQNNKIRVALGLKSRQAESNWKKVQDAAEAKRKRDEKNAAIKRVRDIAQRSVQLQGSTLGEAWLAQSKKRQKELAEREIKVGHSAG-AFGGEDHILTLKDTAVDDELQNLDLVEKERTEEKLELKKK-K--ILSQYDEKRFTLISLDFEPDISEVKIKKPKKKKAKATKQSFVDDDDLQASLALQRRAAEELAK-QLRELVIDETSEFVSNLTLDQ-GLAATLSMLKSRGLVK--ESQNALMRDRLADKLRQQRERDRAR-WENKQRDQDVFNRYKPDV-QL-RYVDEFGRNMNQKEAFKQ-LSHQFHGKG--SGKMKTEKRLKKIDEEKKRESMSTLDSSGMNTAVGTAARKRQAGVR Phybl2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 ISLSVEDTNKLRLQLGLKGLEQAVNFNNHQEQKRRQHNDEKLKNRISDKRQENRNNKRQVSEQLRNNWLANLGKPKTKTTQQDVKIAHSEK-ELLHNNDILTLEDADILDVLTNQKLVDSSKLKKDLKQQAEEE-------VQSVIKLDESEDEGPKKPVKMKKMKKSKSSNSRVDLVDEEDLQSKLTTRRRLKDQIAS-EIARIVFNDTTEFLSSIKFNG-GLAETLNFLQSRNILHKSSERKRREAARLLKIKELESSREYRA-LDQRLKEKGHIGKYNPKV-KL-SYRDNNGDELNTKEAFKY-LSHQFHGVG--PSIGKEEKRKKK--HLEEKEHTT----------------------- Plicr1 ESISLEETNKIRISLGLKDKDKEANYAKQREREAKERESKKIADRIAKVRNKRELNASLKGKTLGDKWIKKAKKREKEQESMDLKVSHDFE-EMEGDARILTLKDSRILDELQNVEMAEDEKTKKNNDLKIK-KRAVLSKYDETGFRLLSIDYAKKEGDVGFKKPKTKKKRPSRRNFVDDDELQAALARSRRAKEDVAK-KIAELTFDDTSEFVRAINFST-GMASTLNILRQQGILSAPASREKTQLQRLVDQREIERLQSRRE-YENRLREQEAFKNYKPDV-NI-VYYDEFGRVLTPKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIAEEKKQEAMASGDTPSMNRAFQIRQEKLSVGTK Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ESLSIEETNKIRISLGLKDPDQQANYNKHRQEEADGVASKKVAERVIKAKENRERLAKLSGRGLGEKWVKRHKKKSAELNADELKVGHDLK-DIEEEKMVLTLKDSKILDELENVELAEQNRTKEAFELKRQ-GQTVLAKYSDKSFRLLSLDYSKEEGDPGFKKKTKKTSKKSKQDVIDDEELQVAMSRMRREAQKSAD-KLD-LVIDDASEFIRTIYVSG-GMASTLSLLKSQGLIKPMTEKERLYKEKLIEQRELEKEKTKRE-YENRMREAEAYRHYKPDV-EI-KYNDEFGRELSRKEAWKA-LSHKFHGKG--SGKAKTEKRIKKIEEEKKLAAMASGDTPGTNEAFRKRQEKLSVGNK Punst1 ESISLEETNKIRISLGLKDPDKIANYEKKRAEDAKAREAKRIKDRIAKLKNQHELNAKLTGVTLGEKWLKRAKKREKELENMDLKVSHDFD-DMEGQEQILTLKDSRVLDVLQNVELAEEERHKKNQELKTK-RRAVLAKYDDTGFRLLSIDYTKQEGDAGFKKPKTKKKRPSRRNFVDDDELQAALARSRRAKEDIAQ-KIVALVFDETSEFVSSITFNS-GMASTLNILRQQGLIATPSEREKVQRQRLAEQRDLEKAKARRE-YENRLREQEMYKNYKPDI-NI-VYHDEFGRELTPKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIAEEKKKEAMISGDTPSMNRAFQMRQEKLSVGNR Rhior3 -SISIEETNALREKLGLPDPEKEANYQKMKQEQEKAKRAEEIKKNIEKSQNRKRNLSKLQGKGLGENWVKKSRTREREIEEMDLKVGHSLS-EFEVGETILTLKDRSILDELTNVNIEDKERVKKNLEAKKK-KQSILPQYEE--FVI--LSYTKEEIEATFKKPKSKKKMRRKTNFVDDDDLQEALSRARRVAEEIAK-QI-KLVLSETSEFVGSLLVSG-GLAATLALLNQKGMIAKPTKRDKIAAEQQNEQREEQKEKERRE-REREREEALAMQNYKPEV-NL-EYTDNKGRVLKTAEAFRF-MSHQFHGKT--SGKTKTEKRMRKIEEERRLNMMSSTDTPNLAGALLERQQRLSVGNR Rhoto1 ESLSLEETNKIRISLGLKDGDALANYRKRREAEQKEKDAADLKSRIDKARNQKERMRKLVGRTLGEAWVKKQKKRAKEQEEADLKVAHDAD-AFEGEDVVLTLKDSRVLDELHNVNMTENAKTKHALELKKKGRRGVLNKYDEDGFQLLSMDYTKQEGEAGFKKPK-KKKRAGRINLIDDDDLQASLARQRREAARSAA-APRPLVLDDTSEFVRNILVSR-GLASTLSLLRHQGLVKPRTAREKEFKARLAAQRERERLESRRE-YENRMRDQEAYANYKPVV-NL-SYHDEFGRDLTPKEAWKQ-LNYDFHGHG--SGAKKKEKRLLKIENERKQAAMAAGDTPSTAAAFAARAEKLGVGNN Rozal11 --------------------------------------------------------------------IKKSKFKIA---------------DLNG-------------------------------------KPNLPENYTI-----LDISYLKMAVDSTIKKSKKKRIRTK--NLIDDFDLQKELSKTRTKNEEIAQ-NILELVISSTSEFVKNLLVRS-GVAATLSLLGQSGVLTSKDDKDALGIEHLAQQREKERLAQK-D-HYKEIQKSEKFKDYKPEI-KL-EYFDDFGRKLAPKDAFRQ-LCYQFHGHK--PGKNKTDKILRKIKEEEDLKMAME----NANSALENARKALTSGNK Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ISLNVEESNALRAKLGLAGQSSMEVLLAPVVPGEKQREAE-LRDKLKERKEKRSVEAKRSVKTLGEAWVKRSRAKKQMLQDMDMTVRHDLD-QFEGAQTILTLEDRGVLDVLVNVNIAEDEHAKR---RVAEAQKSVLDKYDDKTFRIESLEF-KEEEMEKFKKKRKKRAKGRKK-AAEREELQASLTRARRARKDVTE-LLDAVVFSTMSEFVRGINVGS-SVTAALNLALRKGYLAQKK-QQQQEEATLAELTEEHGPEDDRDWRRDSRRDRDPFEKYQPSF-RL-SYTDNTGRELTPKEAFTY-MSHQFHGKT--SGRMKTEKKLRKRQQEEALLKMSSEDTPGSVVGLRKHQEQLSG--- Schco3 ESISLEETNKIRISLGLKSQEETANYKKQREREAKERETKKIQERIAKHRNKRELNASLKGATLGDKWIKRSKKKQKEQEEQELKVNHDFE-ELEGEDRILTLKDSRILDELQNVEMAEHERTKKNNEMKIK-KRAVLAKYDETGFRLLSIDYEKKEGDVGFKKPKKKKKHQARKNFVDDDELQAALARSRRAKEDLAK-KFAELTFDDTTEFVRAVTFKS--MASTLGILRQTGLLATPNDREKTQLQQLAEQREMERLAARRE-YENRMREQETFKHYKPDI-NI-VYYDEFGRSLTPKEAWKA-LSHRFHGKG--SGKAKTEKRLRKIAEERKQQAMSSGDTPSMASAFQARQEKLSVGNR Schpo1 ESISIEETNRIRISLGLKDQEQQANWKKQEQEEINRKKEEELKSKFEKLRQKNERRRRTQGKTLAEAWILKMRNSSL------MKIAHGFQ-DLKNDGLVLTLKDADILDLLENVEMVQRKTKNER-------KQSEADQPSENSLTVVSFVEPT---QIKIKKSKKKKKSDRRKSFADDDDLQQSIAMQRRLAEDVAE-QLQNLIFDDTRAFVNSILVSD-NVGAVLSLLRNKGVIKV-SEKIQKEEEYFARKQRKKKEQDRAK-KENERWDKEQFHDYKPQV-DI-KYVDEFGVELGPKEAYKYLLSHQFHGKG--SGKAKTEKRLRRIVEK-------------------EREER------ Sorma -AASIEELNKVRRAMGMKTREAASNYKKALEADAAKKKREERAAAIKKAREMAQRNAVLDGKGIADAWLKNQKKRQKEKAAAEVKVAHDMD-TFESGDQVLTLRDTGVLDELENIELREREKLNERLDLKKK-KRTILSQYDEKAFTLIDLDMLDDASEIKVKKP-KKKTKSTRRDFVDDDDLQQSLARQRSAAEELAK-QLREIVIDEISEFVDALLVAQ-GMAATFALLKDRCLIDA-EELVKNFRESKAELARIQRERDRQR-QQNTIREQQLFREYKPTV-EL-KYVDADGRSLDQKEAFKE-LSHQFHGKG--SGKGKTDKRLKKLEAERRRMEQSMLDASGMSTAASHQGKKKEAGVR Sphar SAMTWQSS-----SLATT------NLMRNRDSLHQKK-----------------------------FWPNMTKKSTE-----------------------MVLGEYGVV------------------------GQKVLAE--------IAV----TEEMVAFKKPSKKKKKTKSR---DDDELRLALERTRRQKESISA-ALAQLTISANVESIRSL-----GVGQTIK------------EPPAHVRIPIKQEPLLEETKLA-----------EELRDYNPDS-KL-EYYDESGHTIDVKEAFRQ-LSYKFHGIK--PGKAKIEKMMKKRAEQLSLNKMSNTDTPDTVDKLRRKNEALSGQQN Spipu1 IALSIEDTNALRIKLGLKAKQEEANYVKHKEELAKAAQRKALIDRVSKETEKAKRNRQLEGKTLGEEWVRKQKEREEELMEMDLRVDHSLE-DIGGGETILTLKDATIMDILHNVNIADMERNRKNLENKKK-KRNLLSQYDENGFVIVSLSYEKEEM-VSFKKPKKKKVRRERKNFVDDDDLQSALARARRLQEEIAK-AAREVVLSATSEFVRNLLVAS-GLAATVALLSQKGFVEKASERERKQSEKLAEQREIQKEKEKEE-QEARYAERERFRHYIPDV-NL-DYHDEYGRKLNAKEAFRQ-LSHKFHGKA--SGKMKTEKRLKKIEDELKMEKMSSTDTPGTANALLERTKALSVGNR Sporo1 ESLSLEETNKVRISLGLKEGDELANFKKRQEQERRKVEEKELRERIDRARNQKERQRKLAGKGLGESWIKKQKKRAKEQEEMDIKVSHGAD-AFEGEEHVLTLKDSKILDELHNLNLTENAKHAAALDLKKKGRRGVLSKYDEEGFKLLSMDYTKQEGDAGFKKPKMKKKRPARTNLIDDDDLAVSLARQRREAERARL-QVEELVLDDTSEFVRNILVSK-GLASTLSILRHQGLMKPRTRKEKEFKERLVAQRERERIESRRE-YENKLRDQEAYKNYKPVV-EL-KYHDEFGRDMTPKEAWKH-LSHSFHGHG--HGSKKTEKRLQKIENERKAAAMAAGDTPSTAAAFAARAEALGVGNN Stehi1 ESISLEETNKIRISLGLKDKDKQANYAAQRDKEAKDRTAKKIKDQIAKVRNKKELNSSLKGATLGDKWLKKSKKREKELESMDLKVSHDFE-GMEGEARILTLKDSRILDELQNVEMAEEEKTKERNETKIK-RRAVLSKYDETAFRLLSIDYAKQPGDIGFKKPKTKKKRPSRRNFVDDDELQAALARTRRSKEEVAK-KVAELVFDDTSEFVRAITFNS-GMASTLNILRQQGILATPSEREKIQLQRLADQREIEKLRSRRE-YENRLREQEAFKNYKPDV-NI-VYYDEFGRQLGPKEAWKA-LSHKFHGKG--SGKMKTEKRLKKIEEEKKKEAMSSGDTPSMSKAFQMRQEKLSVGNR Tapde11 EGLSIEETNKLRLSLGLKQDQVASNFRQRRAQEDKDRKAREAAERLRKVKERVEREKQIKGKTLAD-WIRRTKTAVKEMVRQHLRVGHDVG-DFNGGETVLTLRDSGVLDELVNVEINEQQALKDKLQRKKR-KRKILARYDEAGFAIISLDDLSEP--VKMRKPKKKKLRKARSNFVDDDDLQASLAKQRRLADQIA--LLRPLVLDETTEFTRGLTFDQ-GVGAAMAMLRQKGVLK--QDSSAK-QTQLAKNKRRVREELRAA-SENRRLDAERF-KYKPNV-EI-KYVDDFGRNMTQKEAFKH-LSHQFHGKD--SGSGKTAKKLAQIEKEKALEQRSLFK-------------------- Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 DSLTLEETNKVRVSLGLADRDEIANYAKRKEDEKRKKEEKEVKERIEKARNRSALNAKLKGSTLGDDWIKKQKKRAKEMEEADLKVSHAAD-EFEGQDIILTLKDSRVLDELQNVNLMDEAKLKAAKERKRKAQADILGKYDEEGFRLLNLDFTKKEGESSFKKPKKKKKRSARRNLVDDDDLQAALSRARREQEDIAA-QIASITFDDTSEFVRNV-LGQ-GLAGVLNVLKQQGTIKSLTEREKVQKQKLADYRELAKVQARRE-WENRVREQELYKSYKPDI-NL-VYHDEFGRQMTPKEAWKS-LSHKFHGKT--SGRMKTQKRLKKINEEQNQVKMSASDTPGMTDAFARRQQKLSVGNK Trire2 -AATIEETNRIRISLGMKSRQAQANYKKLQEEEAAKKRREEKAAAVRKAREKAQRAAILAGKGLGESWLLGQKKRQKELAAAEIKVAHDST-AFDGDEQILTLKDTTIDDELENLNLREQEKLTERLDLKKK-LGTILAQYDEKKFTLISLDDIIAPSEIKVKKPKKKKNKGTRQDFADDDDLQASLAIQRKNAEDIAK-QLK-LVIGEISEFVAGLTVGE-GMGAALALLRERGLID--SGSYEDFKARLAKKRRHQRERDRAR-QQNTHRDHELFNAYKPNV-EL-KYVDDHGRRLDQKEAFKH-LSHQFHGKG--SGKGKTEKLLKKIEDEKRREAQSMFDASGMNLATAQQLKKREAGVR Umbra1 -ELSLEETNRLRIQAGLADEDQVANYQQLKEDRQREKNAKEVMERIEKAKNRQKATEKLKGKGLGDKWIKKSRKREKELAEMDMKVAHDMA-EFDGGEVILTLKDRGILIELTNVNLEERERLRKNQENKKK-KKNLLSQYDETSFVIVDLSYEKEEAALTFKKPK-KKKVRRRVNFVDDDDLQQALARTRRIAEDIAR-NIAQLVISNTSEFVNSLLVSR-GMAATLALLNQKGFIAKPTQREKHAAGRIAEQKERERERDRRE-VEKERKERQRMKDYKPDV-NI-EYTDEFGKVMTPKEAYRV-LSHKFHGKT--SGKAKTEKRLRKMQEELALNSMGSSDTPNLAAAMIDRQEKLSVGNR Ustma22 EELSLEETNKLRISLGLKDGDALANFQDKQDRERRQWEDAEVKERLAKAQAKRDVARRLKGPTLADAWIKESKKRAKELEEQELRVGHNAD-EFEGEERILTLRDAGVLDELMDAALDQAERDAKHLQRKQG-ARGVLAKYDAAGFRLLSLDYDKQEGDVGVKKPKTKKKKAAKVNFVDDDELQASLAKTRRIKEMIAK-NLAELTFDETSEFVRAIVIGR-GMAGAVSFLRQQGMLPQLDTREEQQRKYLSARRELARQASKRE-AQNRNREMDRFRDYKPDV-EI-KYHDEFGRDLDQKEAWKH-LSHVFHGKK--PGTKKMEKRLKKIEDEQKRERMAAGDTPGMLAAFQKRSERLSVGSR Walse1 ----------MRIKIGLKDKEKSANYATLKADEQKQRDDESQREKIAKARNKLELNKRLKGKTLADKWAKRIKRKQKQQAELDLKVAHDIE-DFEGKEHVLTLKDTSVLDELQNLDLAEDERGKERAELRKGVKPSLLSKYDDSGFRLLSLDYLKKEGDVGFKKPKTKKKKSSRKNFIDDDDLQIALAKQRREKEDIAA-EI--LEFDDTSEFIRTVQPGK-GLGGILASLKQQGQIETLTEKERVQQNNLAEQREEEKLRIRRD-FENRQRDAEAFERYKPSV-DI-KYFDETGRSQSTKEAWKY-LNYKFHGKG--QGTKGREKALRKVENERKQLAMTSGETPNMMSSFQARQEALSVGNR Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3030.fasta_al_trimmed; alignment length = 185] Allma1 AIHTDSLSFSYLRKLKLSLPKGARCLLAGANGAGKTSLLRILAGKRLGITYLGPEWIQNPVTRRDLPVSQLLESHNAPDRLAALLHLLEIDPTWRTHEISDGQRRRVQILLGLLQPFDVLLLDE--VTVDLDVLVRKDLLAFLKRESEVRGCTVVYCTHIFDGMWPTHVAHMRHGRIVEGWLRDD Ashgo11 AVEVTGLSYKFLTDVNLVLPWRKRMLLCGSNGAGKSTLLKLLSGKHLVTAYLGTEWCHMAIVHRDIGVQELLDSIGLRERGTELLRILDVDLRWRMHRLSDGQKRRVQLCMGLLKPFKLLLLDE--VTVDLDVVARTKLLHFLRLETERRECSIIYATHIFDGLWPDRVVHIAHGPLALAWLARD Aspfu1 SINVNGLNYKFLTNVSLSLPAGSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGVEWVLNSIVRTDIDVPTLLASVGGPERRDELVEILDIDLRWRMHAVSDGERRRVQLAMGLLRPWQVLLLDE--ITVDLDLLSRSNFLSFLKRETETRPCTIVYATHILDNLWPTHLVHMHLGELVLKWLKED Aurde31 AVDVQHLTFAHLHDLSLQLNHGARVLLIGANGAGKSTLLQLLAGKRMGVTFLGTEWAMNPVVRSDIVVSHFLDSVGGKDRRDRLLDILDIDLDWHMHQISDGERRRVQLCMGLMVPWDVLLLDE--VTVDLDVLVRDDLLAFLKQESEERGATIVYATHIFDGLFPTHIAHMRDGRIALQWLKDD Batde5 AIDVTNLSFDFLKDIDLHLSKGTRTLLVGANGAGKSTLLRLLAGKNLGVTYLGTEWAHNPVVRRDVPVSRLLKSLGAQARCAELLDILDVDPNWHMHQVSDGQRRRVQIVLGLLEPWEVLLLDE--VTVDLDVLVRTDLLNFLKRETVQRNASILYATHIFDGLWPTHIAHVVAGLVVERWLRED Botbo1 AIAVSSLTYSHLVDLYLHLPRGSRTILIGANGAGKSTLLQILAGKRLLVTFLGTEWAMNPVVRSDIVVSNFLDSVGGKERRDKLLDILDVDLDWHMHAISDGERRRVQLCMGLMIPWDLLLLDE--VTVDLDVLVRSDLLDFLKEESVSRGATVLYATHIFDGLFPTHVTHMRSGSLALHWLKED Botci1 SIEVKNLTYKFLTDITLSLPPSSRTLLIGANGAGKTTLLRLLSGKRLGVTYLGLEWVLNPIVRTDIGVRELLTSVGGPERRDELVQVLDIDLEWRMHQVSDGERRRVQLAMGLIRPWRILLLDE--ITVDLDLLSRKRFLDFLREETEKRKCTIVYATHILDNLWPTDLVHMSLGELVLKWLGED Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 AIEVKNLTYEFLQDFNLAIPWGTTNLVVGPNGAGKSTLLRILAGKTLYITYLGTEWATNSIIKRDIPVNLLLASIGGQDRRNLLIDILDIDPSWSMLNISDGERRRVQIAMGLVKPWKLLLLDE--VTIDLDVVVRSKLLNYLKQECQERNCTVVYATHIFDGLWCDRVIHIDAGPLALFWLNKD Cangl AVEVTDLTYRFVENINLKVPWNTRTLVVGANGAGKSTLLKLLSGKHLVSTYLGTEWCHMSIINRDIGVLELLDSIGYKQRGDRLIDILDIDVNWRMHRLSDGQKRRVQLAMGLLKPWRVLLLDE--VTVDLDVIARMRLLDFLKWETTNRKCSVVYATHIFDGLWPDYVLHMQSGPLAIHWLQGD Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 AIHTDSLSFTYLNKLKLSVPRGARCLLVGSNGAGKTTLLRILAGKRLGITYLGPEWVQNPVTKRDLQVSVLLESHNAPDRLAALLHLLEVDPTWRTHQISDGQRRRVQILLGLLNPFDILLLDE--VTVDLDVLVRRDLLAFIRRECEVRGATV---------------------RI-------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SIDVKNLSYAFLKDVFLDLPPGSRTLLIGANGAGKTTLLRLLSGKRMGVTYLGLEWVLNPIVRTDIDVPTLLSSVGGAERRDELVRILDIDLSWRMHAVSDGERRRVQLAMGLLRPWTILLLDE--ITVDLDLLSRSNFLNFLKKETETRPCTIVYATHILDNLWPTHLVHMSLGELVLKWLKED Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 VVDVGGIDFDFLENINLKIQKGSRTLLVGPNGAGKSTLLRVIAGKHLGVTYLGTEWVANKSTRLGISVRELIKASGGPERSEALIRLLDVDENWIMNQVSDGERRRVQIVLGLFIPWRLLLLDE--VTTDLDVLVRSKLFRYLYNETIERDATIIYATHIFDGLWPTQIAHIRSGQVIEGWLAKD Conpu1 TIAVQNLTYHHLNDISLHLPPGSRTILVGANGAGKSTLLQILAGKRLGVTFLGTEWAMNPVVRSDIKVSVFLDSVGGKDRRDQLLDILDVDLDWRMHMISDGERRRVQLCMGLMAPWDVLLLDE--VTVDLDVLVRDELLTFLQNDSITRGATILYATHIFDGLFPTHIAHMRFGSTALQWLKED Copci AIQASNLTYHHLVDINLTLPHGSRTILIGANGAGKSTLLQLLAGKRLGVTFLGTEWAMNPVVRGDITVSAFLDSVGGKERRDHLLDILDIDLDWRMHMISDGERRRVQLCFGLMVPWDILLLDE--VTVDLDVLVRSELLNFLKEDSIKRKATILHATHIFDGLFPTHVAHMRFGNVALRWLQED Croqu1 AIEVTDLHFKFIRGIDLELTPGSRCLLIGANGAGKSTLLQILAGKRLGVTYLGTEWASNPVVRSDLIVSHFLDSIGGKARRDRLLDILDVDLDWHMHELSDGERRRVQIVQGLMAPWSLLLLDE--VTVDLDVMVRQELLEFLIEDTVARGCTVLYATHIFDGLFPTHVCHLQLGVLALHWLTED CryneH991 AIDCQSLTYSWLENVNLELRKGDRCLLLGANGAGKSTLLRILAGKRLGVVYLGTEWSSNPVVRSDIVVSHFLDSVGGKERRDRLLRILDVDLDWHMHQISDGERRRVQLCMGLMGEWDVLLLDE--VTVDLDVLVRADLIDFLISESEIRGATIVYATHIFDGLFPTKICHIQLGELALEWLRED Crypa2 SIEVNKLTYSFVTDISLSVPPRSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGLEWVLNPIVRTDIGVVELLRSVGGPERRDELVHVLDIDTAWRMSAVSDGERRRVQLAMGLVRPWTVLLLDE--ITVDLDVLSRAEFLAWLKRETEARDCTIVYATHILDNLWPTHLVHMHMGEVVLGWLRSD Debha1 AVETIDLTYKFLQDVNLQIPWGSTNLLIGQNGAGKSTLLKILAGKTLLITYLGTEWAANPVVKRDIPVNLLVSSIGGPERRDELIRIMDIDPEWSMAYISDGERRRVQLVMGLLKPWKLLLLDE--VTVDLDVVVRQDLLNFLKKECRLRNCCVIYATHIFDGLWCDRLIHLNEGPLALHWLRDD Dekbr2 SICAEHLCYRYLFDINLKLKRGSRLLLVGPNGAGKSTLLKILAGQRLIVTYLGTEWANNEITQ------LLVESIGGKERRDMLINLLDIDITWRMNQCSDGERRRVQLCMGLLKPWDLLLLDE--VTVDLDVLVRYRLLEFLKKETETRNCTIVYATHIFDGLWPTEIIHLNCGPLALHWLKED Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 AIYVENLTFTHLSNLNLSLPRGSRTLLIGANGAGKSTLLQLLAGKRLRITFLGTEWASNPVVRGDIAVSHFLDSVGGAERRDRLLDLLDVDLDWHMHMISDGERRRVQLVMGLMAPWDVLLLDE--VTVDLDVLVRDELLTFLKKESESRGATILYATHIFDGLFPTSIIHMRLGMTALQWLKGD Fusgr1 RVEVNNLSYTFVNNITLDLPPRSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGLEWVLNPIVRTDIGVNELLSSVGGPDRRDELVAMLDVDTNWRMHAVSDGERRRVQLAMGLLRPWTVLLLDE--ITVDLDVLSRAEFLAWLKNETEIRECTIVYATHILDNLWPTHLAHMHLGELVLSWLRDD Galma1 AISATNLTYSYLIDLSFSLPTGSRTILIGANGAGKSTLLQILAGKKLGVTFLGTEWAMNPVVRGDILVSAFLDSVGGKERRDCLLDILDIDLDWHMHKISDGERRRVQLCFGLMVPWDVLLLDE--VTVDLDVLVRNDLLNFLKADSEERGATILYATHIFDGLFPTHIAHMRFGHVALAWLKQD Ganpr1 TIECTDLTFELLKNLNLALPTASRTLLVGANGAGKSTLLRLLAGKRLGLTYLGTEWATNPVVRGDIAVSQLLQSAGVRERAKELLEVMDVNPLWHMNAVSDGERRRVQIVMGLLAPWSVLLLDE--VTVDLDAVVRSDLLAWLKAETERRGATILYATHIYDGLWPTHVAHMAFGLAVTGWLRAD Gloin1 AIDVEDLTFNFLENVTFKLQKGARCLLVGANGAGKSTLLTILAGKRMGVTYLGTEWANNPVVKGDVLVSTLISNMKGPERVKELIQIMDINPKWRMHQISDGERRRVQLVLGLIKPWTLLLMDE--ITVDLDVLVRSDLLEFLKKETEERNATLLYATHIFDGLWPTHITHIKRGKVVEQWLRED Hisca1 SIQVRNLSYNFLTDVSFDLPSGSRTLLIGANGAGKSTLLRVLSGKRLSVTYLGVEWVLNPIVHTDIDVPTLLASVGGPDRRDQLIQILDIDLNWHMHAVSDGERRRVQLAMGLLRPWTLLLLDE--ITMDLDLLSRSEFLGFLKRETEERECTIVYATHILDNLWPTHLVHMHLGEVVLEWLKRD Klula1 AVEVHDLTYAFIHDLSLSVEWNKKVLVVGNNGAGKSTLLKLLSGKHLLTTYLGTEWASMAIVHRDIGVLELLESIGLRARGEELVRILEVDINWRMFKLSDGQKRRVQLCMGLLKPFKVLLLDE--VTVDLDVVARDRLFQFLDRETRDRQCSVVYATHIFDGLWADEIIHLQDGPLALHWLTRD Lacbi2 AISVTNLSYSHLQDITLHLPPGSRTILIGANGAGKSTLLQLLAGKRLGVTYLGTEWAMNPVVRSDIAVSAFLDSVGGKERRDCLLDLLDIDLDWRLHTISDGERRRVQLCFGLMAPWKILLLDE--VTVDLDVLVRDDLLRFLKADSEERQATILYATHIFDGLFPTHIAHMRFGSIALSWLKDD Lenti61 EISIENLTYSHLANINIHLPKGSRTILVGANGAGKSTLLQILAGKRLGITFLGTEWATNPVVRGDIVVSDFLNSVGGKERRDRLLDILDIDLDWHMHQISDGERRRVQLCMGLMGDWDVLLLDE--VTVDLDVLVRDDLLTFLKQDSVARGATILYATHIFDGLFPTHVAHMHLGSLALQWLKED Malgl1 AVEVHNLCYSFLEGCDLILERGSRCLLIGANGAGKSTLLRLLAGKRLGITYLGTEWAMNPVVRSDISVHDFLNSVGGSERRDHLLDLLDVDLSWRMHMISDGERRRVQLCMGLMEPWDLLLLDE--VTVDLDVQVRCDLLDFLRKESESRGSTIVYATHIFDGIFPTHLVHMQLGSLALAWLRED Mellp23 AIDVTDLHFRFLRGIDLKLTPGSRCLLIGANGAGKSTLLQILAGKRLGVTYLGTEWASNPVVRSDLIVSHFLDSVGGKARRDRLLDILDVDLDWHMHELSDGERRRVQIVQGLMAPWSLLLLDE--VTVDLDVMVRQELLEFLVEDTVKRGCTVLYATHIFDGLFPTHVCHLQLGILALHWLTED Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 SVNVADLTFTYIDHLDLQLDAGNRCILVGANGAGKTTLLRILAGKRMGITYLGTEWANNPVVKSDLSVEYLLKSMGSPDRTELLLHVLDVDVKWRMHQISDGQRRRVQLVMGLLHPWELLLLDE--VTVDLDVVARADFLNFLKIETEERGCTIVYATHIFDGLWATHIAHVADGTLCLQWLRED Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 TVETFNLTYSFVSDITLSLPPRSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGLEWVLNAIVRTDIGVVELLRSVGGPERRDELVSVLDIDTNWRMHAVSDGERRRVQLAMGLIRPWTVLLLDE--ITVDLDVWSRAQFLGWLRRETETRECTVVYATHILDNLWPTHLVHMHLGELVLRWLRDD Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SIEVQNLSYKFLENVSMSLPPGSRTLLIGANGAGKTTLLRLLSGKRLGVTYLGVEWVLNSIVRTDIDVPTLLASVGGPERRDELIDILDVDLRWRMHAVSDGERRRVQLAMGLLRPWQVLLLDE--ITVDLDLLSRSNFLAFLKRETETRACTIVYATHILDNLWPTHLAHMHLGELVLKWLKED Phybl2 SVAVNKLNYGYLKDLSLHLTAGSRCILVGANGTGKTTLLRILAGKRMNVTYLGTEWANNPVVRADLTVEYLLKSMGSPERTKTLLDVLEVDTTWRLHQVSDGQRRRVQLVMGLLHPWKLLLLDE--VTVDLDVWIRAEFLSFLKRETEERGATIIYATHIFDGLWPTHLAHVNEGGLCYRWLRQD Picst3 AIETDHLTYKFLEDITLQIPWGSTNLIVGPNGAGKSTLLKILAGKTLYITYLGTEWAANSVVKRDIPVNLLISSIGGSERRDELLDILDIDPDWSMLRISDGERRRVQIAMGLVKPWKLLLLDE--VTIDLDVIVRQRLLEFLKKECVERRCCVVYATHIFDGLWCDRIIHLDAGPLAVYWLQRD Plicr1 AIAVSKLTYSHLTDIDLHLPRGSRTIIVGANGAGKSTLLQVLAGKRLGVTFLGTEWAMNPVVRGDILVSHFLDSVGGKERRDHLLDILDVDLDWHMHAISDGERRRVQLCMGLMVPWDVLLLDEASVTVDLDVLVRDDLLTFLRKDSETRGATILYATHIFDGLFPTHVAHMRFGSVALQWLKED Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 AVEVSKLFFRFLRDVNLDLERGSRCLLIGANGAGKSTLLQILAGKRMGVAYLGTEWASNSVVRSDLVVSHFLDSVGGKSRRDRLLNILDVDLDWHMHQISDGERRRVQIVQGLMAPWNLLLLDE--VTVDLDVMVRQELLQFLIEDTKTRDCTVVYATHIFDGLFPTHVCHLQIGVLALHWLKED Punst1 AVHVDHLTFAHLENVNIHLPPGSRTILVGANGAGKSTLLQILAGKRLGVTFLGTEWAMNPVVRGDIVVSHFLDSIGGKERRDRLLDILDVDLDWHMHAISDGERRRVQLVMGLMAPWDVLLLDE--VTVDLDVLVRDNLLSFLREECETRNATILYATHIFDGLFPTHVAHMRFGALALQWLSED Rhior3 SVEVNDLTFGYIDHLSLKLDDGNRCILVGANGAGKTTLLRILAGKRMGITYLGTEWANNAIVKSDLSVEYLLKSMGSPERTQELLQVLDVDTAWHMHQISDGQRRRVQLVMGLLHPWRLLLLDE--VTVDLDVLARSDFLSFLKKETEERGCTIVYATHIFDGLWATHIAHVADGTVCLGWLRED Rhoto1 AIAVNNLDFAYLHDVTLNLPKGSRCLLVGANGAGKSTLLQILAGKRLGVTYLGTEWASNPVVRSDLEVAHFLDSVGGKERRDRLLDILDVDLAWHMHEVSDGERRRVQIVSGLMAPWDLLLLDE--VTVDLDVLVRSRLLAFLAEETQTRGATIVYASHIFDGMWPTHLCHIQLGELAVHWLEID Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 AIEVRNLTYKFVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLTTTYLGTEWCHMSIINRDIGVLELLKSIGFRERGERLVRILDIDVRWRMHRLSDGQKRRVQLAMGLLKPWRVLLLDE--VTVDLDVIARARLLEFLKWETETRRCSVVYATHIFDGLWPNQVYHMKSGPLALEWLKRD Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 TITVQNLNFSHLIDITLHIPKGSRTVLVGANGAGKSTLLQVLAGKRMGIAYLGTEWAMNPVVRRDIVVSNFLDSVGGKERRDRLLDILDIDMDWHMHEISDGERRRVQLCFGLMVPWDVLLLDE--VTVDLDVMVRDDLLNFLVQDSEERGATIIYATHIFDGLFPTHVAHMRLGTVALKWLRED Schpo1 EVTVSNLSYTFLDHVTLDLPKGSRTLLVGANGAGKSTLLKLLSGKSLAFVYLGTEWVNNPVIHRDMSVARLIASVGGAERRDFLISILDIDLRWRMHAVSDGERRRVQLCMGLLRPFEVLLLDE--VTVDLDVLARADLLNFLQEETEVRNATIVYATHIFDGLWPTHLVHLSLGETCLEWLKED Sorma TVETTHLTYTFVSDITLSLPPRSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGLEWVLNAIVRTDIGVVELLRSVGGPERRDELVSVLDIDTNWRMHAVSDGERRRVQLAMGLIRPWTVLLLDE--ITVDLDVWSRAQFLGWLRRETETRECTVVYATHILDNLWPTHLVHMHLGELVLRWLRDD Sphar VIEVTGLNYAYLFDVNMKMPKGARCLLVGANGTGKSTLLRILAGKKLGLTYLGSEWANNPITRQDMRVTQLIRSSGGRERRDRLLDILDINPNWRMHE---------------------------------------------------------YATHIFDGIWCTHLCHLSNGRLVEQWLREE Spipu1 AVQVSNLTFGFLKDLSFSVPRGGRCLLVGANGAGKSTLLTILAGKRLNITYLGTEWAHNPIVRRDVPVSRLLRSLGAPDRCAELLEIMDVDPDWHMHEVSDGQRRRVQIVLGLMEPWELLLLDE--VTVDLDVLVRAELLSFLRKETETRNATILYATHIFDGLWPTHVAHIVDGMVVEKWLRDD Sporo1 ALQVEQLEFAYLGNVDLNLPRGSRCILVGANGAGKSTLLQILAGKKLGVTYLGTEWAANPVVRSDLKVSHFLDSVGGKDRRDKLLEIMDVDLDWRMHEVSDGERRRVQIVSGLMEPWEMLLLDE--VTVDLDVLVRSKLLSFLVEETKTRGSTILYATHIFDGLFPTHLCHLQLGELALWWLEQD Stehi1 LVFVDGLTYHHLKDISIHLPPGSRTILVGANGAGKSTLLQILAGKKLGVTHLGTEWAMNPVVRGDILVSDFLDSVGGKERRDHLLDILDVDLDWRMHQISDGERRRVQLCMGLMSPWDVLLLDE--VTVDLDVQVRDDLLTFLREDSEARGSTILYATHIFDGLFPTHVAHMRFGLVALQWLRED Tapde11 SIEVKNLNFSHLSKIDISLEPGSLTLLVGANGAGKSTLLRLLAGKRIGITYLGTEWANNPVVRNDISVSHLLASIGAPDRRDQLLGILDVDLTWRMNRVSDGERRRVQLTMGLMREWKILLLDE--VTVDLDVLARSDLLEFLKQETRARHCTIVYATHIFDGLWPTRLLHMSLGRLCLHWLTVD Thetr AVHVEELSYDYLFDVSLDFAPGTRTLLVGLNGTGKTTLLRILAGKHLGLTFLGAEWAHNPVVRKDVVVADLIVSMGGPDRRDELLALLGVEPTWRMHKVSDGQRRRVQLLLGLLKPWTLLLLDE--VTVDLDVLVRHDLMAWLRHQTETRGATVVYATHIFDGLWATHVVHLCNGQLIEAWLSTE Treme1 AIDVERLTYSFLEDVTLTLHRGSRCLVIGANGAGKSTLLRILAGKRLGVVYLGTEWSSNPVVRGDIVVSDFLDSVGGKERRDRLLRILDVDVDWHMHQISDGERRRVQLCMGLMGHWDVLLLDE--VTVDLDVLVRADLIEFLVEESKIRNATILYATHIFDGLFPTHICHLQLGHLALEWLRED Trire2 QIIVKNLSYTFVRNISLDLPPRSRTLLIGANGAGKTTLLRLLAGKRLGVTYLGLEWVLNPIVRNDIGVMELLRSVGGPARRDELVHMLDIDTNWRMHAVSDGERRRVQLAMGLLRPWTVLFLDE--ITVDLDVLSRFQFLAWLKRETETRECTIVYATHILDNLWPTHLVHMHLGELVMGWLRDD Umbra1 AVQVDNLTFGYLKDLNLRLPRGARCLLVGANGAGKTTLLRILAGKRMGVTYLGTEWAGNPVVRSDLKVDFLVKSVGGPDRRDELIEVLDVDTNWKMHQVSDGQRRRVQLVMGLLAPWDMLLLDE--VTVDLDVLVRSDFLDYLEKETAARNSTIVS----------------------------- Ustma22 AVQVSDLTFTFLEHCNLSLKRGSRCLLIGANGAGKSTLLRLLAGKKLGVTYLGTEWAMNPVVRSDIVVSAFLDSVGGKARRDRLLDILDVDLTWHMHAISDGERRRVQLCMGLMEPWDLLLLDE--VTVDLDVQVRADLLDFLQQETEERHATIIYATHIFDGLFPTHLAHMRLGNVSLAWLRED Walse1 AISVRDLNFSFLKNINLDIEQGSRCLLVGANGAGKSTLLRILAGKRLGITYLGTEWAMNPVVRGDIRVSEFLDSVGGKDRRNILLDILDVDLDWRMHQISDGERRRVQLVMGLMVPWTLLLLDE--VTVDLDVVVRSDLINFLITESKERNATILYATHIFDGLFPTHVLHLRLGKLALGWLRED Zygro1 ALEVNGLTYKFLVDINLRIPWNTRTLVVGANGAGKSTLLKVLSGKHL-TNYLGTEWCHMSIINRDIGVLELLESIGLKERGELLCNILDIDVHWRMFKLSDGQKRRVQLAMGLLRPCKVLLIDE--VTVDLDVVARQRLLKFLEYETRTRKCSVVYATHIFDGLWPNQLIHMRMGPLAMKWLVKD [Cluster3033.fasta_al_trimmed; alignment length = 284] Allma1 --SAS-AAVILDEANMAFLQRKHEATTLFSQV-AEAGSDHP-RCADVLFRYGRALLNHAIDRSGLLG---GFFHF----DEEEHEGGEENDEDEDEPAAEED-DFEIAFESLDVARVLYEITGKGVRHRHAEVVATLGDVSLESESFGQAVDDYTTALALHTAL-LADRQLAELHYKLALALE-YEQALDHLVQARNVMQGCHDLLADQLE-----IAKELAELQG-LLPELDLK--VQDVKTAIAAATKATLDPNAVNDLSALV-KKKSKAA-NESPKKPKLS Ashgo11 -----EIQGLLAQAAKAYASENFEAAELYAAV-NEA-HVEP----DFLFLYGRALWRAAAAAGDVLG--------GA-E----------------------S-DLEAAWEVLELARTLYEASGD-VQQKLAETYDVLGEVSLEAENFGQAAEDLRSCLALR-----EERLLVEAHYKLALALE-YAECCAQLQRCVDMLGARV-AAGTGA------LQQKLADVAE-VAPDALAG--LREQL------------AA-VNDLTSRV-RRRGG------------- Aspfu1 DPIK-QLEDLIARAVAKDAIKDFNAAELYSQA-TELGELSL-DNADLLFSYGKALYNVAVSKSDVLGNQ-AFFQFSG-DDSDSEA--EE-GD-GADG--ADD-DFANAFEVLDLARILYH-CEEGIKERLADTYDLQAEISLEGERFTDAVADLRTALDLRQSL-FSDPSLAECHYKLSLALE-FEEAATQMEKAIESCRARMAQEQKKL------LRRKIANVKE-IIEDMEQR--LLDLRTMLRGILPA-VEQQAAKDLSALV---KRKSA-PENTKKARTE Aurde31 ASEAAGLDAPVERARKAVALKNWSAIEQYSIA-LEYGEKPPIEYADLYFDYGKALLESAISSNAVLGSD-ARFHFGG-DDAQKEG--ADDDDDQANGGDE-D-DFNAAWEVLDVARTLYEDADA-LKLRLADTLIALGDISLETEKFDQAIDDYSAGLKLKQEL-LPSRHIAEAHFKLSIAYD-LKGAIEHVQGAIASVEARIAELRCGLKGKGKAIETEIKELTG-LKEELGVK--LEELKTLLKNELAT-SSSA-INDLTGMV-KRKKDKA-EDS-KKARVE Batde5 TASDEDIPTLLAAGAQAYAMSNFSAAEKLSIA-SQLGQKSR-ESAEILFHYGRALLANAVQKNSLLGKA-GHFVFNG-DECAEEQ--VERAD-DENGGDDG--DLEIAWETFDLVRIIYT-----DKKKLGEVYMALGDVSLESGNFEQAITDFLTALRIKEET-LDDRELAEAHYKLALALE-YEDAIVQVTQTTTVLEKHLHKLTNRDKGKKAAVSKEIKEVES-LLAEMSAK--MFDLGETIGNELTS------TTDVSGLV-KKTAKTA-ETASKKPKV- Botbo1 TKDASTLESHIELGKRAFALRKYEAVDHYGSA-LELGDDSSLEYANLLFVYGKALLENGISQSAVLGKS-DRFHFGG-DEAPIEE--------EGEEEDDGD-DFNAAWEVLDLARAIFE--DS-SKLKLGDVYVALGDVSLETEKFDQAITDFTAAVKLKMEL-FPSRQIAEAHYKLSMTLD-LSDAIEHAAKALESVQARLAILRDAAKGKGRALQSQIKEFEE-LETDLNLK--LEDLKEQAEKELAS-SATP-VNDLTSMV-RKKKAKA-QEEKKKSRVD Botci1 EP---SLAEYCAKGTAEYAQKRYDAVDHYAQA-AELGEMSP-ENAEILFLYGRALFKVAQQQSDVLG-K-PLFTFTG-DDSDEEE--EE-------AEEEDD-PLNIAFDILDLTRVLFEDEGEGIKERLADTRDLLGEISLENERFPAAVADFKESLALKQSL-FPDEQIAEAHYKLSLALE-FAEAVKELELAIKSTKLKLHNQEVEL-------RHRIADVKS-IVADMELR--LKELRNAMSGILSA-SDTAA----------KKPK-------RQLRI- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -----EVAKLISEGSRAYSSKDFDASEKYGEA-CEEGN----EDADLLFLYGKAVFQSGVSKSEVFGTD-DTFQFYA-D---NEE--PNEDENDED-----S-DFEVAWELLDLARALFEDTDESVLKKLSETYDILGEVSLEAENFNQAADDLRKCLELRLEL-FSSSLISESHYKLALALE-FKNAAEQMKLAIESVERRN----------------KRKENQE-IIDEMKEK--YQDLLDIIKGILQS-AGAA-VNNLQTMV-KKKQNKK-QD--KKLKSE Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow EPTTALIAERMQQGRRQMLCEEYLAVDCFQEA-VETGELAD-ECGEPFFQYGSALLAAARAESQVFE------------KAANQD--QENDDDNEQGQDDED-NLQLAWENLECARVIFA-----ARLALASVHARLGEHSVESEQFDQAFTDFKECLHIRESI-LPDRSIAELLFTMAIAYQ-LNESVDSLQRAMTVMNMRLRYLRSGE------IDQEINDLTE-LIPDIRSK--IAEINSAAGAAVSS-SSSAAVNTLQ--V-RRKVAGA-ED--KKARLD Catan2 SPAKS-LATLLDEANLAFGQRNYESAMLFSQV-AEAGTVHP-KCADVHFRYGRALLNHAIERSGILG-----FHFSE-DDQEQEE--EEDEDQDGAPGQDQD-DFEIAFEVLDVARVIYS-TNKGVKRRYAEVVATLADVSLESESFGQAVDDYSQALVLQSEL-YADRRLAETHYKLALALE-YDRALEHLHAARNVLVARRDELAD-LK-----TRAEMAEISNELLPELELK--VEDVTEAAASSTKKALGDN-VNDLSGLV-KKKS-EA-EESPKKAKLD Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 EPLATKLSELSQVASIHYSTKNFPAAENYANA-VEIGEMAP-ENAELLFYYGRALYKVAVAKSDVLGNK-PYFQLQG-DDSEDED--DE----AQDG-EQED-DFGNAYEIFELARVLYEDKGKGIKERIADCHGFLVEISLENERFHDAVADARKSLALQEEL-YPHENVTEAHYSLSLALE-FKEAAEQTDLAIQSLEARLKKEEAAL-------QAIINDKKG-MLEDLKTR--LVELKSVFQGLLDA-ATQKAANDVSGMV-KRKAKGA-DE--KRAKTE Coere1 SETVAVIADLLEVGTRAFALGNWEAIENFGEL-SSIGSESQ-RYADCLVMYGRALLQHAIEQNALLASK-ANINFEG-EQKAADS--GMEEG-SSKGKQVDD-DFAAAWDILDLARVIQEESDS-TRLKYAETLMLLGDVSMESENFAQAVNDFSDALNVKLQY-LDNRELAELYYKVALAHE-YAKALDLMKDVQRILGNRLKNLEI--------DKEDVTSLKE-VLEDVAAK--VEEWK------LSAVAERAKIKDISNLVKPNKKRGA-TD--KRAKGN Conco1 QPQENAIDNSLQIGNKFLMNEEYEAIEQFSAA-VQVGEKHI-NSAFPNYKYGYALFKSAVANRRALD---SNIQI---DQVEDDD--DEAEDEGEDGEGDED-DLTFSYHVLSGSLNIYK-----LRDQMCQVYIAMGDASLESENFENAIENYKEAESNIREY-FGLRRLSEVLFLLGMAYE-YQQSQKVFEEVKTLLTKRKSELDLEK------EKEEDKDLDQ-LIKEVNER--IQDAIENLSSVI---KEKETARDVSSLI-KRKRNEASSN--KEAKTE Conpu1 QAT--TVEGALEQARRAFALRRYEAVEHYAMA-LEIGEDAP-EMADLYFSYGKALLENAIVQSQVLGNG-AFLSFSG-DNAAKAE--EEEEEEEGEGEEE-D-DFNAAWEVLELARAIYDKEDD-VTLKLADTYIALGDVSLETEKFDQAITDYEEGLKIKLEL-LPSRQIAEAHYKLTLALD-LSDAIVHAEKALDSVEHRLAELRTGIKGKGKGMEKEIKEVEG-LREDLAMK--VEELKAMAARALAG-SATA-VNDLTSMV-VKKKKKA-EDS-KKAKLE Copci AKPTNTVELAVEQAKRAFALKKYEAVEHYATA-LEIGEDAP-ETADLYFSYGRALLENAISQSSVLGNG-PILSFSG-DQP-------EDDD-ESDEEGD-D-DFNAAWEVLDLARAIYEDEDD-VRLKLADTFIALGDVSLETEKFDQAITDYQSGLDLKLKL-LPSRQIAEAHYKLSMVLD-LADAIGHVEKALESVEHRLAELRNGLKGKGKQIENEIKDLDE-LKVDLALK--IEELKELAAKALAS-SS---VNDLTSIV-KKKKKKA-ESE-KKARLE Croqu1 EPPDEIIEINISEGIKSFALKNYRSINYFSKS-CEIDDQHP-KLIDIQLLYGKALVKNAVKLNSVL-NN-PMIHFSGDD-------SDEDGDDGEEAEEDGE-EFESAFQILELVKLSIQIKKE-YQTKLIQVFELLAEVHQETECFQLALEAYQNSLEIKHIL-LSYRSIAETHLYIALVYEIMLKAIEHIEKSIELVKKHINLL----------IKEEIEECKL-ILIDLNLK--LDELKKAFQDYLN---ANEAVNDLSNLV-KKKK-ETIED--KRSKLD CryneH991 APSSSEVEKLVAEGKKAVALHQWEGVDRYATA-LDRGDADP-EMAPLLLAYGKALYDLASSQAGVMGNN-LNFVFSG-DPEPEPE--SE-PQATDAAEGDED-DYNAAWEVLDVARTIYEEGEG-ERMLLSDCYLALGNVSCETENFPQAVQDFTAAVDIQNTI-IPFRDLASAHYQLATALE-FTSALTHVESALSSL-VRR-------KEELLSKEAEMKDVEA-LMGDLQAK--IEELKDLIHESIEA-SGSG-VNDLTGMV-KKKKPAA-E-A-KKAKNE Crypa2 AP---SLADLTARASGHYAQKRFEAAEIYAQA-AEMGEMAV-ENAEILFLYGRSLFKVGQEKSDVLGKK-PLFQFTG-DDSDEED--GAEGE-GE-GEDEED-DLASAFEILDLARVLFKGEGKGIKERLADTYDRLAEISLENERYPNAIADMREALRYNQEL-LPSELIAEAHFKLSLALE-FDEAAKELEAAIASTKLKLQNKEVEL-------RSQIADVKD-MIADLEQR--LVDLR--VGGILSA-VETEAATDLTGLV-RKKGKKA-EEASKKPRTE Debha1 -----GINELVAEGAKLYAAKEFDASEKYAEA-CENGE----EDADLLLLYGKSLFQSAVLKSEVFG-D-GNFQFCD-DAAAEEE--EEEESGEAD---KQS-DFEVAWEILDLTRSLFEDNEETLTKKLSETYDLLGEVSLEAENFPQSAIDLQNCLDLRLKL-YNSSLISESHYKLSLALE-FSKACEQMRLAIESVRDRN----------------KKKDNDD-LVQDLEVR--YQELENIIKGILDK-SPVA-VNDLSSVV-KKK--KP-TS--KKSKK- Dekbr2 -----EITKVLNEGARAMAAKQYEAVELYSEA-CELDEDDP----DLLYLYGWSLFENAVASSDVLGDG-GMMQFND-IELNQDE--SKNTN-NLEKEGDDS-DFEIAWDILDLTRTILEDKDDDLKKKLADVYALLGDISLETDNFAQAGSDLNSMIKLRKEL-FPSGSLTEGFYKLSLALE-FGGSIDAMKQALKTIKKR--------QSQGEHMRQRLYDLIK-AEKDIIMKGILGELSALATKQSKQ-KAQPLVHDLTSSV-HKRRSKH-SS-------- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba APAEQAVIDTVRKSIKSFTQNDDDSSELFKRLASDVMEMDD-DFANDHFTYGVALFEGAVRSVDPFQ---PAAAATG-N--------DEAAD---------D-DFDEAWEMFEIARLHFE-----NRLGLARVHNYLGQIYIDDANAELALAEFDKSASFLDRD-NPARRFAELDFNRLRAHL-LDEAIATLRTSANTATTASSDLADLIQAKRRELEAEYGNMSE-AFSDVAAGFGLGSSR-------VS------ISDIQSVV-RKKRK---E--------- Fomme1 NTS--LIQNNVEQAKRAVALRKYEAVEFYATA-LELGDESP-EAADLYFIYGKALLENAISQTAVLGN--PFISFSG-DEANAAV--EAEEKENAEEAQDGD-DFNAAWECLDLARALFEDEDD-VKLKLADTYIALGDVSLETEKFELAIPDYEAGLALKTSL-LPSRQIAEAHYKLSMVLD-LAQAISHAEKALESVESRLAEMRTGLKGKGKAIEKEIKELEG-LREDLGLK--VEELKELAAKALST-TTVKAVNDLNQMV-RKKKKKA-EEESKKAKVE Fusgr1 APVVDTLADLSAKGAALYARKSYEAAEVFSRA-SILGETSP-DNAEILFHYGRSLFKVGQSKSDVLGKK-ALFQFTG-DESDEEE--NAE------GDEDED-DLATAFEILDLARVCYL--ESGVKERLADTHDALSEISLENERYPNAIEDGRTSLKYKLEL-YPSEIIAEAHFKLSLALE-FDEAVKEMELAIKSSKLKLQNKEVEL-------RKSIQEMKE-VIGDMEQR--LVDLR--IGGILSA-AETKAANDLSGLV-RKKNKKA-EEEAKKTKVE Galma1 SAT--TVDSAIEQAKRAFALKKYEAVDHYATA-LELGENAP-QTADLYFSYGKALLENAIAQSSVLGNG-PILSFSG-DEAAKEQ--EEEDA--GDEEE--D-DFNAAWEVLDLARAIYNDEDEDVGLKLADTYIALGDVSLETEKFDQAITDYEAGLKLKIGL-LPSRQIAEAHYKLSMVLD-LSDAITHAEKALESVESRLTELRTGLKGKGKSIESEIKELAE-LRDDLVLK--IEELKVLAAEALAS-SSSS-VNDLTSIV-KKKKKKA-EGD-KRPRLD Ganpr1 SPTLARIGALLEEGKNLYKLSQFEAAAKLGQA-AAFSHISP-ESGDVFFWYGKTLLKTAIQSAGLF---------SG-DEAEDDD--DDDDD---------D-DFTLAWEVLEIARTVYEASPDG-KARLAQVFMLQGEVGLEDDNPPQSVQSFHSALSLKKSY-LPHRELVEVHHLLGLALE-TEAAVEQFRMAKKVLEGRREEILAERKGKGKAGHDEVKDIEE-LIPELEDK--IADLSSA---LLDARKQLAAVNDVSGLV-KKRKVRA-DE-------- Gloin1 SSSANTIRLLTEEGTKAFKLKDYEAVLKYEEA-SQLGNSE--EFADALFNYGKALIENSIFQTSVLGNN-SHIYFEG-EEESLEK--EINNNDHAETTNESDSDLNVANDVLIIARDIYL-----SKASLGEVFMKLGDISLEQENFDQAVVDYREAVKVKSER-LSNMELTEAHWRLALALS-ADQAIEHVERAMEVLNKCKKNLLEKLYGKGKQIEKKLNEIDQ-FLIEMEAK--IEELNEIALAEYSAESGSTTINDITSLI-KRKVVKV-ENEGRSGEND Hisca1 SLIREQLADLIERASAKDAIKDYDAAELYSRA-TELGEMSV-ENADLLYSYGKSLYNLAVRKSDVLGSS-SLFQFTG-DSGSDEE--ND-GD-G-DGAQEED-EFANAFEMLDLSRILLLKQDEEVKERLADIYDLQAEICLEAERFEDAVTDLRASLELKTEL-FPDASVAECHYKLSLALE-FNEAANHMETAIRSCKLRISKELQKL------IKSNIEDVKE-IVSDMEQR--LIELRNALNGILSSDTDKATANDLSLLVRKKKRTTA-DE--KRVRLD Klula1 QINCLKFDKLLTEGAKHYAGKNYEAVDSYADL-NQLENPNP----EYLFLYGKALYQLALSRSDVFGGP-GLIQFGE-EEEEEEE--EEEEEEKQDQEQEED-DFENAWEILELARSYYEETPDNLKLKLSECYDLLGEVSLECENFSQASHDFEECLKLRREL-FEDRSIIESYYKISLALE-FKKCTSNLQKCIELLKQRCKTVDKED------LQTKLKELQS-LKNDLLST--IHSVTA------KS-NEAP-VNDLTSMV-KKR-KSA-ET--KKAKN- Lacbi2 AAKN-SIETAIEHAKRAFALRKYEAIDHYATA-LELGEDAP-ESADLYFLYGKALLENAIVQSSVLGTG-PILSFSG-DQATHLE--EEE----GDDEEV-D-DFNAAWEVLDLARAIYDQEDDNVKLKLADTYIALGDVSLETEKFDQAITDYEAGLKLKVQL-LPSRQIAEAHYKLSMVLD-LADAIVHVEKALESVETRLAELRNGSKGKGKSIDNEIKELSG-LRDDLSLK--VEELKALAAQALSA-SAVA-VNDLTSMV-VKRKKKA-ETE-KKSRLD Lenti61 SETVTSLKDTIEHAKRAFALRKYEAVEHYASA-LELGEKAP-ETADLYFAYGKALLENAIAQSGVLGAG-AFLSFSG-DEAQKAI--EEADAAQAEEEED-D-DFNASWEVLDLARAIYEDESD-VKLKLADVFITLGDVSLETEKFDQAITDYTAGLALKTEL-LPSRQIAEAHYKLSIVLD-LGDSITHAERALDSVEARLAELRAALKGKGKAMEAEEKELQG-LREDLALK--VEELKALAAKALAA-APV--VNDLTGLV-KKKKKKA-EGE-KKAKLD Malgl1 -----SRRN---------------------------GDDAP-ELAPILHSYGRALLEHIIATSGALGKD-SCFEFRN-DEEESEP--QQPDDPEEESENEQD-DMGVAFTVLDLSRVIFESLSKG-QIELAEVRNDLGDIGLETENFEQASVDYEASLNLLAPL-IPARRLSDAHLRLGLALE-FKLAKDYINRAADVLQRRLDQISH-I------IRREEKDVQE-MLQDLRVK--VSD-------AH------HD--------------------------- Mellp23 KPPNESIQSDLAEGSKSFALKNYQATDSFSRA-CETGDQHP-AVVDAQILYGKALVKHAIKLNACLGTN-PHIHFSG-D-------SDEDEDQEEKAGSDEE-ELEAAFYVLELARSSI-LSDESLKKKLIQVFELLAEVHQEGDKFDEALNSYLSSLKVKESL-PTRRSMAETHLWTALAYE-LSKSVEHVENAIELMKTYI-----------------------------------EKLKIALQAYLN---ENGTVNDLSMLV-KRKKNE--EDMNKKSKVD Mnele EDNTGQIPKLQQQINRQFATDNYKAVSACEQL-CSLDELHD-ECAEPYYQYATALLEVARDENQILA------------DNEAGP--SEEEEGGGDGDEEES-SLQIAWEVLELSRIIYS------QRKLAKVKIKLGEVCMENEKLDEAIVHFTEAIEHFKKCGEESREISSTYYMMGLSAS-LEDAIKHFSQCSQLMASQISKLQG----------SDSDSLRE-MKVEVDKM--VSDCKSTSSPSSVFPTSSNSVSNISHLV-RKRPV-A-EEEAKRSRQ- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 DPETE-IQALNDVGAKAFALQDYEAVEKFGLA-SEMGETNT-KCADTLFMYGKALLEHAIQQSSVLG---PRFVF----DDDEDE--DEGEDGGGEGGAGGD-DFAVAWDVLDLARVLFH---------LGDVHIALGDVSLESENFEQAVNDYREAITIKEAR-LEDRQLAEAHYKLALALE-YTQ--EHIHKASNVLKDRIQKLNG-LK-----MAAELVELHE-LVGEMEQK--TQDLITQLAML-EVLVQQKAAIDISSLI-KPKST-A-EEGEKKPKVF Mucci2 AKAQE----LFDQGKLAFNKGEYESVTKLGEA-CQLGDLAP-ANGDAYFLYGQALLQFAIQQNTVLGKN-PLFQLSG-VQGQD----EEDDD-DEDEEDDEDEDFETAWDILDVARLIFE--ED-SKLNLADVHLCLGDVSLETEKFNEALSDYEKAIEIKQSV-LENRELAEAHYKYALALE-FDQALPELQKAVNVLKKRISNLEAGKKGKATDALEEIKEINE-LIPDMELK--IEELAAMLKAMLLT-ASTPVANDVSNLV--KRKAGG-EK--KKPKLD Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 TPA--SLADLSAHAAAQYAQKNYDAAELYAQA-AEMGEMNP-DNAEILFLYGRALFKVGQSKSDVLGKK-PLFHFEG-DDSDKEE--EDDDE-AEEGEEEDD-DLAVAFQVLDLARVLFEEEGKGIKERLGDLHDLLAEISLENERYPAAITDSRASLKYKQQL-YTSEIIAEAHFKLSLALE-FDEAAAELEAAIASTKLKLQNKEVEL-------RRQIADVKE-VISDMEQR--LVDLR--VSG--SS-LKVA-ANDLTGLV-KKKRKPA-EEEAKKVKEE Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -----QLDDLIARAAAKDATKDHDASELYSQA-TELGELSP-ENADLLYAYGKSLYNVAVSKSDVLGSK-PFFQFTG-DDSEDED--EEAGE-GED----ED-DFANAYEVLDLARVLYLDGGKGIKERIADTHDLQAEISLEGERFSEAVTDLRTVLELRNSL-YPDPSVAECHYKLSLALE-FKEAAIQMEHAIASCKVRMAQEEKKL------TKRKIANVKE-IVTEMEQR--LVDLRAMLKGVLSA-TDQKAATDLSAFV---KRKAA-EEGSKRSRVD Phybl2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 -----EVNKLLADGSRAYSSKNYEASEKYGEA-CEKGD----EDADLLFLYGKSLFQNAVLKSEVFG-G-DKFQFFD-VQDEEEE--ADEENAEVDQEEQES-DFELAWEMFDITRNLLEDDEETLTKKLSETYDLLGEVSLESENFPQSAQDLKSSLQLRLKL-YNSALISESHYKLSLALE-FQSAVEHMKLAIDSVKKRN----------------KKKENEE-LIQDLDAR--YQELKDIIKGILSS-GSAA-VNDLSGIV-KKK--KA-PG--KK---- Plicr1 QQSNAGLDDAIEHAKRAFALKKYEAVDYYATA-LELGDDAP-ETADLYLVYGKALLENAISQATVLGSG-AILSFSG-DQALREA--QETEA-DGEEEEDDD-DFNAAWEVLDLARAIFDDEDD-VKLKLAETYITLGDVSLETEKFDQAINDYTAGLAIKTEL-LPSRQIAEAHYKLSMVLD-LADAIVHSEKALESVETRLAELRDGAKGKGKAIEAEIKEVEG-LRDDLALK--VEELKALAAQALSA-TSST-VNDLTSMV-VKKKKKA-DEA-KKAKVE Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 KAKEETIEAELAAGARAFAFKNYAATECFSKA-CEKPQNHS-AIIDAHLSYGKALLRNAITLGS-LSGN-PQIHFSG-D-------SDEEGDE----EGDED-ELENAFQVLEFARQSILSSKD-LQNKLIDVYDLIAQVHQEGEQFEQAVESYKSSLEIKKSR---AGAIAETHLMIALALE-LKQAIGHVDEAIELMRAQLAKLTQKSKGKGKSLKLDREETQS-LIAELEAK--REELKKALQVYLNPSTTNGKINDLTNLV-KKRARPTITTPSKKLKTS Punst1 -----TVETAVEHAKRAFALKKYEAAELYAVA-LEIGQDAP-ETADLYFSYGRALLENAIAQSSVLGNG-AFISFSG-DEAAKDV--EAEDA-KEEQEED-D-DFNAAWEVLELARAIYADADD-IKLKLADTYITLGDVSLETEKFDQAISDYRAGLALKEEL-LPSRQLAEAHYKLSLVLD-MSEAIVHAQRALDSTEARLTELRDRLKGKGKAVEAEIRELSE-LKEDLALK--VEELGELVAKVLGS-AST--VNDLTSMV-KKKKKKA-DDD-KKAKLE Rhior3 NKAQA----LIKEGSEALYDKKYSSIEKLGEA-CQLGDLAP-ENGDAYFMYGKALLQYAIEQNTVLGSN-PLIQMES-IDENDVG--EEEGE-EEEEEGNED-DFETAWNILDAARIIFE--DD-TQLKLADVHLCLADVSLEIEKFDDSLGDYEKAIEIKEKY-LENRELAEAYYRHALALE-FDDALPALQKAISVLKKRSNKLKQAE----ADITKEIKELEE-LVSDMDLK--VEELTNMLKQMLNT-KQS--INDLSNFV--KRK-DA-KD--KKPKLE Rhoto1 -PPAA-------RGIRALALRKYSACDFLAQA-LESGDLAP-ENVESLVLYGKALLGSAIAQSAVLGSN-PNFHFGG-D--------DSDEDGEGEDAPSGD-DLESAFQMLDLARTILT-DGKG-EEKLAEVHRLLGDVATESEQFDNAVEEYTSSLSLLSRL-LPDRALSELHMLTALALE-FSRAVSHAEKAKSVLVSKLAELEG--K-----VRREIEDIKG-LMGDVDMK--IEDLRSALEALLAEAAASG-VNDLTGLV-KRKKK-AEKET-KKVKVG Rozal11 NPCTTGADTVINVKDVSTVVKNQETVSVEEKSFLELGQLAP-ECVEVYYEYGMALLKYAIENSALLN---KVIDFED-EQKQEEKGTSEDNEKSKEGEEVQD-DFHLAWEVLDVARVILEEGDEN-KLKLADVHAALGEISIENENFKQAEEDFSNAIKLKESI---EREIAELYFKKALALE-YNEAIENMKVALEKLTKRKEEFSKKKKGKEKAINREIQDLEI-LFPDLEAK--IEDLK----------SNNQ-INDLSNLI-KKKPK---ENDSKKTKIE Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 SST--TLESAVDNGKRAFALKKFEAVDHYATA-LEIPEDSI-ELADLHFTYGKALLENAIANSGVLGGG-PFLSFSG-DQAAKEV--AAADAAEGAGEEDDD-DFNAAWEVLEVARSIYDSASEGLKLKLAEAYISLGDVSLETEKFEQAILDYEEGTKLKDAL-LPSRQLAEAHYKLSMVLD-MSDAIRHAELALKSLELRKAELGEALKGKGKAIEAEIKDLDS-LLEDLGLK--VGRVA-----------------------------S------------ Schpo1 SKGNSAIEQLVTQGNMAYAQKNYEAVDKYGQA-LMQGSESL-ENRNVLWLYGKSLFQIAIENSQVLG-----FTFSG-QEKESEE--KETNE-SPASEEDED-DFNVAWEVLDLTRVMQS-----EKIRLADIYDLLGELSLEIENFSQASQDLKTALEWKEKV-YNNTLLSEAHYKLALALE-FSRACEHVEKAAEILKNVLNERENEVKGKGKQLTSDLENLRE-MLSELEQK--TLDLKSLEEAVMSKDSSSLAANDLGGLV-KRKRTEG-PK--KKKKD- Sorma TPA--SLADLSAQAAAQYAQKNYNAAELYAQA-AEMGEMNP-DNAEILFLYGRALFKIGQSKSDVLGKK-PLFHFEG-DDSDEEE--EEGD--AEAEEEEDD-DLAVAFQVLDLSRVLFEEEGKGIKERLGDLHDLLAEISLENERYPAAITDSRASLKYKQQL-YTSEIIAEAHFKLSLALE-FDEAATELEAAIASTKLKLQNKEVEL-------KRQIADVKE-VIADMEQR--LIDLG--VSGS-ES-LKVA-ANDLTGLV-KRKRKPA-EEEAKKVKEE Sphar NTATEKADHIRREAKLLYTNRDYSAVEKYVEV-LEVGELGA-ECGELFLWYGDSLLQVLRENLQLID-----------D----------------------E-EFEDCWNVLEVARVIFE------SSMLAMTHRKLGNLNNDVEEYEKAIEDYKKAIALYEAL-PEDRAVAELHFFTGLSHS--AEARASYQKAAKILKRCL-------------VPTETKELQE-IIDDLNLK--IEDTYKLVRRAKNANSSAGGVIDLSSFV-KRKKPTG-ETSPKKPKTD Spipu1 SATNSEAIQMLETGEKFIIEKQYEAAEELSRA-VSAGDGAP-ECADALYLYGRALYFLAVEKSSVFG---SRFIFEG-D-AENVE--EIPAQ---------E-DMEIAYEALTVAATAYQDSEAS-NRRLADVYLLIGHYHLEGDRPREALEEYKKTLEIRERY-PEHRELAEARYYVALTLE-GPQALDEVKRAMADMSKRLEELKAIKSSKGKAQSEEIKELTE-MITDLEAK--VEELHSAVNKVVSPELKKEDVTDISSLV-KKRKAKL-DAAAGEAKVE Sporo1 EPSTT-------QGIRYLALSKYAAAESLSYA-VEDGELSI-ENVDALVLYGKALLANAIEQSAVLGSNSAAFHFGG-D--------DEDEDEEGDQEQEGD-DFESAFVVLDMARRAIE-MKEG-KEKLAEVHRVLGDVATESEHFEDAVEEYSSALSILTKL-RLDRILSELHMLIALALE-FGRAVSHAEKSKGVLIKRLGELEN--R-----DKREIQDIKE-LVVDVDAK--IEDLKLTLQEIMAAGSSPGPINNLNSLV-KKKKK-A-TDG-KKAKLS Stehi1 DASKSTIESSIDHAKRAFALRKYEAVDHYATA-LELGEDGA-EMADVYLAYGKALLENAIQQAGVLGSK-AFLSFSG-DEASKAA--AEADAGGADEEEEED-DFNAAWEVLDLARAIYEEEDEDITLKLADTYIALGDISLETEKFEQGISDYTSGLALKSSL-LPSRQLAEAHYKLSMVLD-LADAILHAQKALESVEARLAELQAGIKGKGKAIQAEKKELEE-LKGDLAAK--VEELKEMVARALGS-GATA-VNDLTTMV-KKKKKKA-DEE-KKARLE Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------GEQHP-STAPFYVAYGKALLDCARAKGNVLS--------------------D-------------D-DLTIAWEVLELARVIYSAAAAG-AQRQAEVHCTIGEVCLESDNMDGAIKEYTAAAEIYSKT-LPDGAVAEVYYLLGTSQQ-L----GHHTDAEASFTKAADAVAAAIK-----LSSKIADRRG-ILAEISDK--IAETKTASSASSKPSAAST-VNDLSSLV-KRKPA-A---QPKAKK-- Treme1 TPAEPEADKLVAEGKKAIALRKWEGVGKYGQA-LDIGEFDP-AMAPLLLSYGKALYELAVSTQGALGSS-GNLIISA-DDDDAPE--EEAPQ----EEGE-D-DFNAAWDVLDMARTIYEDSES-VKLNLAQCYVALGDVSCETENFVQAVQDYTSALNLQTPL-LPSRVLASVHYQLSSVLE-FAEALDHVHSALKGFQARQ-------KNETSSLENELKDVVS-LIDDLEAK--IEELKDFVKESISS-SSSF-VNDLSGLV-KKKPPGV-EFG-EKRKAE Trire2 APAVETLADLSAKGTALYAQKKYEAADIFSRA-SILGETAP-ENAEILFHYGRSLFKVGQSKSDVLGKK-VFFQFTG-DESDEDE--AQE------GDEDED-DLATAFEILDLARVCYLDGDKGIKERLAETHDCLAEISLENERYPNAIEDGRTSLNYKMEL-YPSEIIAEAHYKLSLALE-FDEAIKEMELAIKSFKLKMQAIEVDI-------RKAVEEMKE-VIVDLEQR--LVDLR--LGGILSA-ADVQAAVDLTGLV-RKK--KA-DDETKRTKVE Umbra1 QPSQE---AIIHEGSRAFSLHDYEATDKFGQA-CELGELAP-QCADAYFMYGKALLQNAIQQNSVLGSN-PRFHFEG-EEVEAEG--DDEAD-DEEGQEDQD-MFNDAWDVLDIARVIYG--SS-ARLKLADVYSCLGDVSLETEKFDQAIPDFQSALSIKQSI-LDNRELAELHYKLALAFE-YHQAIEETRNAVKVLRNRLSTLKEKQKGKGKEIQKEIDEIQE-LIPDMEVK--IEELKDMLKEMLPA-VPIPTVNDLSSLV-KKRKAAP-EK--KQPKNE Ustma22 NPKPDSARQLIDEAKRHFALKEYAASDKLALA-LEEAEDAD-ELAPILQLYGQSVLENFILNSGALGSD-PRFSFTG-DDEESAP------DA------AAD-DLQTAFSVLDLARVIYK------QAELAEVMNLLGDVGLESENFTQASADYRSSLNILLPL-LNSRRLADAHLRLGLALE-FKGAKPHVQAASDVLAAR---IAA-IKEQEKELQKELSDVQQ-LKKELDTK--LEEYEDAFLGAHASKSAAADVNNLSSMV-KRKKK-A-----KKPRTQ Walse1 --------------------------------------MSV-ESAGLLLKYGESLYLHAVSQSHVIGQS-GLIQLSD-DEEAPND--EQEGQ---------D-DFGAAWEVADLAKVIYQEGDDN-KLSLADSHMLLGDIALELETFDEAAAEYKNSLDIKQSI-LNSRVLAEAHFKLAISYE-LEDALVHVKQAKDVLQGRLDDLKKRVEGDTPAANKHIQDISE-LIQDLTLK--IDELESTVDAIVQTISSDAPVNVLQ----PKKKQKA-ED--KKAKMV Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3038.fasta_al_trimmed; alignment length = 70] Allma1 ---------------------------------------------------------------------- Ashgo11 TVTALKYIARNTALPTRARMEAQLQTRMTQVRNRCIATGHARSVI--TDFRLCRTQFREKAKNGELPGVK Aspfu1 ERQALRYIIRNTTLPQRVRAQAQLQTRPTQIKNRCVAGGIARSVI--RDFRIARYQFRQQALNGELPGVK Aurde31 LRRAYLSVSRNQTLPAKVRYQAQLQTRPAQVKNRCVESGRGRGII--GEFGLCRFQFRLKALSGQLPGVE Batde5 QRQALRLIIKDETLPVRVR--AQLESQPSAIKNRCIIGGKSRGYI--SEFRMSQIEFRQHALCGELPGVK Botbo1 LRRAYLYVARNRTLPGTVRAQAQLQTRPTTVKNRCTETGRGRGIM--SKFGLCRFQFRLNALKGEIPGVK Botci1 ERQALRYIIRNLSLPPRVRFQAQLETRPTQIRNRCILGGKGRGIL--RDFKMSRYNFRMNALSGDLPGVK Caeel DRMRLKAIKFNTILPQAIRDEAAEKDHPRLILNMCQFTGRQRGKI--KPYRLSRHLFRRFADRSALSGVQ Canalb1 TRNALKYIARNEELPARARVEAQLQTSAIQIKDRCVASGNAKSVI--RDFKLNRTEFRNRARAGLIPGVK Cangl TAKALKYIARNTTLPPRARLEAQLQTRLTQVKNRCIESGHARAVL--SDFRLCRYQFRERALKGELPGVK Capow ---------------------------------------------------------------------- Catan2 LRNALRFMTRNEQLPSPVRFNAQTSARKPAVRNRCLETGRARWVI--RDFGLTRHVFRDMARKGELPGVS Cioin LYTRLQCIRYSGHLPLELKQVADQESDKNWTVNRCVVTSRPRGNK--DKWRISRMVFRHFADHGKMSGVK CocheC53 ERQALRYIIRNTTLPQRVRAQAQLQTRFTQIKNRCIMGGKGRGVF--SDFRLGRYQFRVNALAGNLPGVK Coere1 QRTIWRYMSRNTTLEPQVRMQAQLAACPTAIKNRCIATGRGRGIF--NKWKLCRFQFRIRALNGELPGVD Conco1 LRQAYRYIARNEANPTRIRYQAQLAACPTTISPRCVETGRGRGIL--SDFRLCRYQFRMKALRGELPGVQ Conpu1 ---------------------------------------------------------------------- Copci LRRAYLYVARNETLPAQVRHQAQLQTRPTTVKNRCIISGRGRGVM--SDFGLCRFQFRLKALRGELNGVQ Croqu1 LRRAYLYVARNETLPMKIRAQAQLSSHPTKIHERCIISGKGRGVI--AKLGLCRHQLKLKATKDKWMGFE CryneH991 QRRAFLYVARNTTLPATVRHKAQLGGRMGAVKNRCWETGRGRGVI--SKFGLCRFQFRTKALSGELPGVH Crypa2 ERQALRYIIRNTTLPPRVRSEAQLHTNPTQIRNRCILGGKGRGIF--RDFKMSRYNFRLQAIAGSLPGVQ Debha1 TRNALRYIARNTELLARVRLEAQLQTSYSQIKNRCVASGHAKSVL--TDFKLNRVCLYQEVNMT------ Dekbr2 TTRALKFIARNAALPQKVRLEAQIQTRSTQLKGRCLDTGRGRGIL--RDFRLCRYQFRLQALQGLLPGVK Dicdi MKNMYKMLRRNELLDQETRNYFNMKSSISRIKNRCVETGRSRGII--SAYRISRLRFREYMKMGLISGVK Dmel ERLRVNSLRKNDILPPELREVADAESSLVRVRERCALTSRPRGVV--HKYRLSRIVWRHLADYNKLSGVQ Enthi ---------------------------------------------------------------------- Falba EILKIKFIRDNKIQNEEYTNTFSNKCHSSRIMNRCIFTGRARAVI--RLARINRISFKDAAERGKLVGIK Fomme1 ---------------------------------------------------------------------- Fusgr1 ERQALRYIIRNTTLPPRVRAEAQLQTRPTQIRNRCIMGGQGRGIL--SDFKLSRYNFRMEAMAGNLPGVK Galma1 ARRAYLFVARNEALPPQVRHHAQLQTRPTTVKNRCHESGKGRGII--SEFGLSRFQFRVKALNGEIPGVH Ganpr1 ERNALRYIVRNQTIPLTTRVQAGAVARKHAIVNRCTETGMARGVV--TPYRLSRINFRQQALDGIIPGVA Gloin1 IRQAYRFITRNEQVHPRIRQHAQLMARPSTIRNRCTETGRARGIF--RDSRLCRYQFRLKALNGEIPGVK Hisca1 ERQALRYLVRNTSLPMRVRAQAQLKTNPTQIKNRCTAGGIARGVF--RDFRLGRFQFRMQALAGKLPGVR Klula1 TVKALKFIARNTTLPPRSRMEAQLQTRMTQIKNRCIETGHSRSVL--SDFRLCRSQFRELARKGDLPGVK Lacbi2 ARRAYLYVARNETLPPQVRHQAQLQTRPTTVKNRCIVSGKGRGII--SEFGLCRFQFRMHALRGELNGVQ Lenti61 LRRAYLYVARNQTLPAQVRFQAQLQTRPSTVKNRCTETGRGRGVI--SEFGLCRFQFRQKALANELPGVK Malgl1 ---------------------------------------------------------------------- Mellp23 LRKAYLYVSRNETLPVKIRAQAQLSSHPTKIHERCIVSGKGRGVI--AKLGLCRHQLKLKATRDKWMGFE Mnele DRLQLETISESDLLPAKIKAQAAADSHKNTETDKCALTGHILGCV--NDYKINRKIFRDLAMKGNISGIK Monbr NHITYNALIKNQILPLSVKYNLLEK--TSHIRNKCLLTGRSRGNL--PKYGLSRIMFTELASEGLIPGMT Morel2 VRQAFRYLTHNTALPAKVRAQAQLQARPTAIHNRCLETGRGRGVL--RAFRLCRFQFRLKALEGELPGVR Mucci2 TRQAFRYITRNETLPARVRHQAQLQSSPTYIHNRCVATGHGNGVL--REFKLCRFQFRLKALNGELPGVK Mydma ---------------------------------------------------------------------- Neucr2 ERQALRYVIRNTTLPARTRAVAQLQTRPTQIRNRCILGGKSRGIL--RDFKMTRYNFRMNALMGNIPGVK Orpsp11 ---------------------------------------------------------------------- Pench1 ERQALRYMIRNTSLPGRVRAQAQLQTRPTQIKNRCVASGTARSVF--RDFRINRYQFRMQALAGELPGVK Phybl2 TRQAYRFVTRNETLPARVRHQAQLMSSPTYIHNRCVATGHGSGIL--REFKLCRFQFRLKALNGELPGVK Picst3 TRKALKYIARNTELPPRARLEAQLQTSYNQIRDRCVATGNSKSLI--RDFKLNRTAFRDRARAGLIPGVK Plicr1 LRRAYLYVARNQSLPPQVRHQAQLQTLPSTVKNRCHESGRGRGII--SEFGLCRHQFRLKALKGELPGVK Polpo ---------------------------------------------------------------------- Pucgr2 LRRAYLYLARNEGLPMKLRAQAQLSSHPTKIHERCIITGKGRGVI--AKLGLCRHQLKLKATRDKWMGFE Punst1 ---------------------------------------------------------------------- Rhior3 VRQAFKYITRNETMPARVRHQAQLQTSSTYIHNRCVATGHGSGVL--REFKLCRFQFRLKALNGELPGVK Rhoto1 LRQALKYLTQNTTLDYRTRVAAMHKTRPTEIRNRCILSGRGRGAIASKEFGLARHRFKLAAERGELPGVE Rozal11 ---------------------------------------------------------------------- Sacce1 LVKSLKFIARNMNLPTKLRLEAQLKMRSTQIKNRCVDSGHARFVL--SDFRLCRYQFRENALKGNLPGVK Salro ---------------------------------------------------------------------- Schco3 ARRAYLYISRNQLLPPAVRHQAQLQTRPTTVKNRCVETGRGRGII--SDFGLCRFQFRLKALRGELNGVK Schpo1 ERQSNLYIYRNPELPLRVRLEAKKRAHPTKIKNRCIETGRGRGVF--RAFGLARFPFRLKALANKLPGVR Sorma ERQALRYVIRNTTLPARTRAVAQLQTRPTQIRNRCIFGGKSRGVL--RDFKMTRYNFRMNALMGNIPGVK Sphar ---------------------------------------------------------------------- Spipu1 TREALRLIARDKTLNDRIR--AQLESRPTAVHNRCVESGKTRGHV--TDFKVSRIVFRERALAGEIPGVK Sporo1 LRRAYLYIVRNETIDQKVRSAAMLKTRPSAIKNRCTETGRGGGVL--SEFGLCRHRFKLAAEKGDIPGVS Stehi1 ---------------------------------------------------------------------- Tapde11 LRQALRYISRNTTLAPRARAQAQLQTRINQVKNRCVETARGRGVF--RDFRICRYQFRLKALDGELPGVK Thetr ---------------------------------------------------------------------- Treme1 ERRALLAVARNTSLPPATRHRAQLGGFTGRVKNRCTETGRGRGVM--SKFGLCRFQFRTKALAGEIPGMH Trire2 ERQALRYVIRNTTLPPRVRATAQLQTRPTQIRNRCIMGGQGRGVL--RAFKMTRFNFRMEALAGNLPGVK Umbra1 IRQAYRYITRNETLPARTRHQAQLATAPVFLRNRCLETGHGSGVF--REFRLCRFQFRLKALNGELPGVK Ustma22 VRRAFKYIARNTTLPQKVRHQAQLQTRPVSVSNRCTETGRGRGII--SEFGLCRYQFRMKALAGDLPGVK Walse1 QRRAYLYVARNTELPFQVRHQAQLSSRPTMIRNRCKVTGRGAGLQQ----GLTRFQFRLQALRDELEGVH Zygro1 TQRALKYIARNTTLPAKARLEAQLRMRQTQIKNRCFETGNARAVF--SDFRLCRTQFREKAKQGDLPGVK [Cluster3042.fasta_al_trimmed; alignment length = 106] Allma1 ---------------------------------------------------------------------------------------------------------- Ashgo11 ---------------------------------------------------------------------------------------------------------- Aspfu1 LLDFEDESTTMADRA-VG-GFSTANLDGSISTKLPERTGYAAFRNKLALRVKRYTVNIQTDSIHQHRLWETILLPFHSFVRTNHGLVLLRQRVKSVGIGLTGPYDL Aurde31 LFKFHNEADVGSDKD-IG-GMSSARMDGNLSLDVA-KSGYAGFRNRLVLRVRGIYVNLQTADLWQHKLWEDVYLPLDKFQLTTGGKLMDRRRVWMFGISVLGLFEL Batde5 LFRLNSVQDVGSDAD-IG-GLSEAYWGGTLSTELPNRSGYAGVRSKLAIRAKQWFINLRTTSVWQHRLWETIMIPFRDFILTSHGFVMDRSAIKTVGLSILGDFSV Botbo1 LFTFRSKEDTGCDAD-IG-GTSSCTLDGDMRLDVK-KGGYAGFRNRLALRVRGYFVNLQTDGLWQHRLWEDVLIPIDSFVLTNSGETMMSQRIRTIGISLLGRYEL Botci1 ----------------TN-GLSEADLE--------GRKEEGQLKSK----------------------WGE-----DKFDKTTS---------------------- Caeel DYRFDTQEKIGCDSD-WKEGFSTCSLVGNISTKVLERAGWASMKLELLLKVRSYKIMLHS--SFSHPLWQYEKIPFSKFFHTVAGRIVNLEDTSSIGIVLMGDFRL Canalb1 VLNFKREPETRSDQE-LG-GYSTVNFDGNLSLDLPTRSGYAMFRTKLVLRVKKYLVNIQANTLFQHRLWETVVIPLNDFVMTNWGVILNKGEVKSVGIGLLGPYSL Cangl ---------------------------------------------------------------------------------------------------------- Capow LYDFSQPRDVTSDAA-FG-GFSRANLDGVLSQAKPVRSGFAAIRSKVELILRTYISNLSTDSVYQSFVWERILLPFARYLLTYHGYVFNKRAIRTFGFSLAGPFAL Catan2 ---------------------------------------------------------------------------------------------------------- Cioin IYYFRNSGEIMTDED-VG-ARSWAELVGYLNNTPPNFYGFAYVETKFKIRLRKYHFETLCDFMYTAPIWQEVTIPFAKLIASIDSGAMALDRMSNFRFLIRGPFHL CocheC53 LILFNQSEDRMSDQD-IG-GFSSANLDGSISTQLPQRTGYAGWRTLLAIQFKKYFVNVQTESIHQHLLWETILIKWNEFVRTNHGQVMLTQKVRTVGISLIGPYDL Coere1 VASVNHKEDKGTDRD-IG-GFSDAWLDGYLSQKLPKRSGYALVRTQLAIRVKKYFINLKSDAIYQHLLWETVVIPFNMFTLTSNSVIMYATKMESVGFSITGPFSL Conco1 LTEFKKEEDVGCDRD-IG-GKSEANLVGFTSNHLPKVHGYAALRTKLLLRVKKYMVNIQTDGIYQHRLWENVLIPFNDFTLTNDGNLMFREKVKTVGIGLIGEFNL Conpu1 LLSLQNREDSGCDAD-IG-GTSSVRLDGEMNLTVK-RGGYAGFRSKLALRMRSYFVNLQTDGLWQHRLWEDIFIPLENFVLTNTGEMMLRERVRTIGISLLGPYDL Copci LFTFNTQQDTGCDAD-IG-GNSSVNIDGTMRLDVK-RGGYAGFRNKLALRLRSYYVNIQTAGLWQHRLWEDLFIPFTNFVRTNAGEVMYRERVKSIGISILGRYEL Croqu1 IFELTRPVDIGSDAD-VG-GLSTVQLAGVLRAELGKRGGYAGFRTKLRLRVRKYYVNIQTEGIFQHRLWEDVLIPFSDFALTNKGEVMPRDEIRTVGISVLGSFEL CryneH991 IFSFTSTHQTGSDAQ-LG-GLTTADLKGYMSTAVP-RTGFAGFRNTLRIVVARWVVNIGVD-----------------------------DRPR------------ Crypa2 LYSFHSRESVFSDAD-MG-GFSKAQLDGSISTQLPERSGYAAWKTLLALRIKSYLVNIQTESLHQHRLWETVLIRFNDFVRTNHGFVMLRQKVRTVGIGLTGPFDL Debha1 VLDFKNNAQTRCDQE-MG-GFSSVNFNGYLNLDVPTRSGYAMFRTRLVMRIKKYLVNIQANTLFQHRLWETVVIPLNDFVMTNWGVIMNKSEVKTIGIGLLGPYSL Dekbr2 LLDFSNLKTTTSDSV-LG-GYSTAYVDGNLNQTLPKQSGWAMFKTKIHLRVAKFMLNVQSDTLFQHRLWEDLFVNIDDLVLTNRGQVFERDRVKSVGLSISGPFNL Dicdi LFSFRQQQKIVTDQE-VG-GFTTAAFKGIISKKLPKSTGYAG----ISVRVKTYSIALLKSCMYKSIFWETVEVPLNEFFKVHKGVVIETKGIDSIGFVQTGEFNL Dmel VFDFKAPDVVTTDAD-HGEGKSTATLEGQVNSDHTKRTGYANIRTKLVMKVRSYLINLHTEGIYHYVLWQIAKIPFSKFFLSSKGRVIPLNRVTHFGFSVAGPFGL Enthi ---------------------------------------------------------------------------------------------------------- Falba LLSIVSAERVGADSD-YG-GYSYALMEGYVSYLTPDQSGYAYARSLVDVCVRMYNLSLSASSLFQNVI------PLGPFRV------IARASVSSFGLSPAGPFRL Fomme1 ---------------------------------------------------------------------------------------------------------- Fusgr1 LYDFNTPESVMSDKT-IG-GFSQSNFDGNISTRLPERTGFAGFRSPLALRVKSYFVNVQTESLHQHRLWETVLIKWNDFVRTNHGFVMLRQKVLTVGVGLTGPFEL Galma1 LYSFNSPENTGCDAD-IG-GLSSVHLDGEMRLQVK-RGGYAGFRNKLALRLRSYFVNIQTDGLWQHRLWEDVFVPFNNFVRTNAGEMMYREKIKSIGISILGKYEL Ganpr1 MYTLNSKEDVGTDAD-LG-GKTTASLEGVLSTEVPANLGYAAMRTKLAVRCRQWFVNIQTHNLYQHRLWETVLIPFRDFILTNHGWIMDRMRVRTIGFSIAGPFEL Gloin1 LLQFNNAKEIGCDKD-IG-GFSNASLEGNISLDIPTRSGYAGIRSRLAIKARKYFVNIQTDGLFQHRLWE--IIPFRDFILTNHGIVMYRERVKTIGFSILGSFCL Hisca1 LLDFTDENTTMSDRA-VG-GYSTANLDGSISTKLPQRTGYAAFRNQLALRVKRYKVNIQTDSIHQHRLWETILIRWNDFVRTNLGFAMVRQRIKSIGLGLTGPYDL Klula1 ---------------------------------------------------------------------------------------------------------- Lacbi2 LFSFNTKEDTGCDAD-IG-GNSTVHLDGEMRLDVK-RGGYAGFRNMLALRLRSYYVNLQTDGLWQHRLWEDIFIPFDNFVRTNSGEMMYREKIRSVGISLLGKFEL Lenti61 LFTFNSHEDTGCDAD-VG-GTSTVNFAGEMNLAVR-RGGYAGFRSKLALRVRSYFVNLQTDGLWQHRLWEDVFIPFKDFVLTNAGELMYRERVRTIGVSLLGPYEL Malgl1 FYKINNSADTGSDSD-IG-GLSRCHMSGTLSSQIPERSGYAAFRNKLALLVRLFFVNIQTDGLYQHRLWQTITIPFDSFVLTNTGVVMMREKILTVGISAL----- Mellp23 IFELTRPSDIGSDAD-VG-GLSTVQLAGVLKNELGKRGGYAGFRTKLRLRVRKYYVNIQTEGIFQHRLWEDVLIPFSNFALTNKGEVMPRDEIRTIGISVLGVYEL Mnele LWKFRGEEDTLDDNM-TG-GRSLIELSGKIDPTPSDGTGYAGIRSYFEFRVRCYRIQLWFKSFWVAHLWERIKIPFNRFYPIKYEQIPPTMKLYSLGI---GDFSL Monbr LFDLTLPETVATDKDFFG-GFSEAQVEGHLSTTIPERSGFALLRSRLEFEVRPYIINLQSSSLYQAFLWQTVQIPLADFLLTHMGYVLSHERIRTIGFLLAGPFQL Morel2 MASLKTDEDVGCDKD-IG-GFSEANLEGQLSLDLPEKSGYAGCRTKLQLKVKKYFVNLQTDGLYQHRLWETVLIPFKDFILTNQGFIIFRERVKNVGISIIGPFEL Mucci2 MATLKTEKDIGSDKD-IG-GFSEASLDGHISLDLPKQSGYAAIRTILALHVKKYFVNIQTDGLFQHRLWETVMIPFKDFILTNNGMIMFRQKVKTVGISLMGPFSI Mydma LFDFRRPETCLTDSE-VG-GKSTASITGEVSMMLEDFTGFCGIRSKVEIKYRPYFVNVQTGSLFQAFLWEIERIPFSKFYQTYKGFAMQFNNIRTIGISLTGPFNL Neucr2 IHNFQTPESLLSDAD-VG-GSSTAHLDGTISLELPSRTGYAGFRTLLAMRVKSYFVNVRTESLHQHRLWETVLIKWNDFVRTNHGKVMLRQKVLSIGFSTTGPYEL Orpsp11 ---------------------------------------------------------------------------------------------------------- Pench1 LLNFEDESTTMADRA-VG-GFSTASLDGSISTKLPERTGYAAFRNQLALRIKRYTVNVQTDAIHQHRLWETVLLPFNSFVRTNHGFVLTRQRVKSIGIGLTGPFDL Phybl2 MAALNSKKDIGCDKD-IG-GFTEASLDGNLSLELPQHSGYAAIRSKLGLRVKKYFVNIQTDGLHQHRLWETVMIPFRDFILTNNGMIMFREKVKTVGVSLMGPFKL Picst3 VLDFKQHGDTRSDKE-MG-GYSTVHFEGYLSLDLPTRSGYAMFRTKLVLRVKKYLVNIQTNTLFQHRLWETVVIPLNDFVMTNWGVIINKSEVKTVGIGLLGPYSL Plicr1 LFTLNSQEETGCDGD-IG-GLSTASLTGEMRLGVK-RAGYAGFRSRLALRLRSYYVNLQTDTLWQHRLWEDVYIPLHNFVLTNSGDLMSRSKVCTIGVSLLGPYEL Polpo ---------------------------------------------------------------------------------------------------------- Pucgr2 IFEMSHPSHLGCDAD-MG-GYSTIQLAGTLRSELGKAGGYAGFRTRLRLRVKKYFVNIQTEGIFQHRLWEDVLIPLADFALTNKGQIMPRESIRTVGISVLGPYEL Punst1 LFTMNTPEDIMSDKD-IG-GSSTVNFDGVLSTKVP-RSGYVGFRNNLALRVRSYFVNIQTDDLWQHRLWEDVFIPFDNFLLTQGGVLMNKWKIKSVGISLLGSYEL Rhior3 LASLNTKNDTGCDKD-IG-GFSEAHLEGNISLELPKQSGYAALRTKLALRVKRYFVNIQTDGLFQHRLWETVMIPFKDFVLTNNGMIMFRQKVRTVGISLMGPFKI Rhoto1 MYTLRSLEDTGSDAD-LG-GKSTVHLDGKLSSELNERGGYAGFRIKLRLRVKRYFVNIQTDGLFQHRLWTDVIIPLNDFTLTNSGMLMMRNAIRTVGISVLGRYEL Rozal11 ---------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------- Salro LFQFRTANDCTSDKKAFG-GHSTAKVEGNLSTKLPVRSGFCLLRTQIEFEIRAYIANLQPDTLHQATIWQTVQIPLTEFLLTYRGYVINGDKIKTLGILLAGPFQL Schco3 LLALNTPEDTGCDSD-VG-GRSTAKLEGEMRLDVQ-RSGYAGFRSMLALRVRSYFVNIQTEGLWQHRLWEDVYIPFDNFVRKNAGEIMPRNQLRTIGVSILGPYEL Schpo1 ---------------------------------------------------------------------------------------------------------- Sorma IHNFQTPESLLSDAD-VG-GASTAHLDGTISLELPSRTGYAGFRTLLAMRVKSYFVNVRTESLHQHRLWQTVLIKWNDFVRTNHGKVMLRQKVLSIGFSTTGPYEL Sphar LFSFRNSTDVTSDAS-MG-GFSKAEKVGTLSTAVPKNSGYCALRSKLEIRLRAYAVNIQTDGLYQTFLWETVRLPLRDFALTFRGFMLNASNVRTIGFLLAGPFNL Spipu1 LFQFQNVEDVGSDAD-IG-GLSEAYWGGSLSTDIPDRSGYAGVRSKLAIRAKQWFVNLQTDSLWQHRLWEVIMIPFRDFVLTSHGYVMDRSKIKTVGFSLVGDFSL Sporo1 ---------------------------------------------------------------------------------------------------------- Stehi1 LFTMNSLEDTGCDAD-VG-GTSTAHLDGDMRLGVR-RGGYAGFRNKLALRLRSYFVNVQTDTIWQHRLWEEVFIPFDAFVLTNAGEIMNRGRIRTVGVSLLGSYEL Tapde11 LFTF--PADVGSDAD-YK-STSTSTVSG-------AGDGYAAMRSKLTLRLRRYFINLQTESLYQHRVWENVTLKWNDFTLTNNGQIMDKYRLKTVGISVLGKFEL Thetr -----EPLEVVTDET-IQ-GSSRATAEGELSTTPA-RSGFASFRTVFEIVCRPYQFNVGCESLHQAALWAVVRIPFDALIMTWRGFVLDSRRITSLGFTLAGPFEL Treme1 IFSFSSASSLGSDID-IG-GLSTAFLTGNMSLVVP-RTGYAAFRNKLRLVVGRWVVNIQTDGLFQHRLFTTLHLPLAEFVLTNSGQTMLRERVRTIGFGLLGPVEM Trire2 LYDFHSADSVMSDTL-IG-GSSTSHLDGHISTSLPQRTGYAAFRTPLALRVKAYYVNVQTESLHQHRLWETVLIRWNDFVRTNHGFVLLRQRVHTVGIGLTGPFEL Umbra1 MFTMNTSKDIGCDKD-IG-GFSEAKLEGNLSLELPQQSGYAAIRSKLALRVRKYFVNIQTDGLYQHRLWQTVMIPFRDFVLTNNGMIMMRERVKTVGISITGPFEI Ustma22 LYAMTQPAHTGSDSD-IG-GLSQCRLGGTLSSQVPEKSGYAGFRNRLALRVRKFFVNVQTDGLFQHRLWQTVVIPFDDFVLTNTGQIMMREKIRTIGISAVFNFDL Walse1 ------SSDVGCDAD-IG-GKSEAILDGVLNPFVPAKSGYAGFRTKLAMRVR-FFINIQTEGLFQHRLWQTLVVPLSSFVLTNAGETMLREKIRTVGLSLLENFDL Zygro1 ---------------------------------------------------------------------------------------------------------- [Cluster3043.fasta_al_trimmed; alignment length = 61] Allma1 ------------------------------------------------------------- Ashgo11 TRAGVLHLYREFVRSARQFNNYNFREYFMRHSRDTFRRAQQEVGVLKRQSVISQMYKLVVE Aspfu1 TAFQVRSLFRSLLRQSSQFSNYNFREYARRRTRDAFRDGLQNLRMLKRQTVISQFYKLVVE Aurde31 TRTSILHLYGSMLRASRSFTSYNFRQYFIRRTRSTFRNGLHELLVLRRAAIVNSLYRLVVE Batde5 ------------------------------------------------------------- Botbo1 TRAQVLSLYGNLLRASNSFYSYNFREYFVRNTRQRFRDGLRELNVIRQAAAMNRLYRLVVE Botci1 ASQQARSLYRQLLRQGGQFAAYNFREYAKRRTRDSFRKGLKELQSLKRQTVVSQFFRLVVE Caeel ------------------------------------------------------------- Canalb1 NSKQILSLYKQLLEKAYKFDNYNFKEYSKRKIVETFKEGINQLALLYRQTTISQLYKLVVE Cangl ARQQVLQLYKQIIKNANQFSNYNFREYFLRKARTEFKGAQRDLGVLKRQSIISQMYKLVVE Capow SKRDTLRLYRHLLQTGRKFQDYNYREYSLRFIRDSFHKGNASLAMLQRQTTINAMFPLVIE Catan2 ------------------------------------------------------------- Cioin ------------------------------------------------------------- CocheC53 VAYQVRSLYRSLLRQSNQFAAYNFREYAKRRTRDAFRKGLSELQMLKRQTVISQFYRLVVE Coere1 KQSQILHLYRSSLRAAQRFETYNFRKYFYRRTHDRFHEARAELEVMQRQGILNKMFRTVIE Conco1 ------------------------------------------------------------- Conpu1 TKQAIRHLYSNTLAAAKSFSSYNFRNYFVQRTEDTFRQAEKDLAVLKRCAIVNQIYKLAVE Copci SKQAILSLYHNMLRSSQSFSSYNFRQYFVKKTKDTFRQAVKDSAVLRRSAIVNQLYKLAVE Croqu1 SRQHISALQSIYLTTSSQFASYNFREYFLRRSNLKFQESVEELEVLQRASVMNRLYKLVVE CryneH991 TVQQIQSLYSATVNASQRFTSYNFHKYFLRRTDEIFKHQKTQLEILERASEVNRMYKLVVE Crypa2 SAHQVKSLYRQLLRQGEQFASYNFREYAKRRTRDAFRKGLKELQMLKRQTVVSQFFKLVVE Debha1 NSKQILGLYKQLLEKAYKFDNYNFREFAKRKVVDSFKEGINQLAMLQRQTTISQMFKVVVE Dekbr2 SPQKVLALYRNILRASYQFEYYNFRLYFLRRTRAEFRKGMKDLALLRRQSIISEMFKLVVE Dicdi -KSVVLHLYRSLVRESKKFSSYNFREYSLRRVSVGFRDALKNLEMVKRQAFINSMYKLVVE Dmel TRRQAITLYRNLLRESEKLPSYNFRMYAARKIRDTFREGQQNLELIRRQVIIGHLYKLVIE Enthi ------------------------------------------------------------- Falba TLAQFRSIYRSLMRAGRGFHAYHYRTYAQRRVRDAFRECQNTLGLIQRQALINRLYPIVIE Fomme1 TAQAIRQLYHSTLRASRSFSSYNFRQYFLQRTNDTFRNAVQEFTVLQRSAIVNRLYRLVVE Fusgr1 MSQQVRSLYRQLLRQGSQFSAYNFREYAKRRTRDAFRHGIKELQSLKRQTVISQFYRLVVE Galma1 SRQAILSLYHNMMRSSQSFSSYNFREYFLRRTKDKFREAVKESTVLHRSAIVNQLYKLAVE Ganpr1 ------------------------------------------------------------- Gloin1 NRTYILHLYRSLLRASQKFSSYNFRDYAYRRIRDSYHKAERELGVLKRQGYLNSLYRLVVE Hisca1 ------------------------------------------------------------- Klula1 SKTQILHMYKEFIRNASKIQNYNFREYFLRRARESFREAEKDLGVLKRQSVISNMYKLVVE Lacbi2 SRQAILSLYHNMLRTSQSFSSYNFREYFIRRTKDTFRDAVKEFTVLRRSAIVNQLYKLAVE Lenti61 TKQSILHLYHSMLRTSQSFSSYNFRHYFVRRTKEMFREKAKELAVLKRSAIVNQLYKLVVE Malgl1 TREQILSLYRAHLATARSFASYNFREYFVRRARDQFREACDELKVLQRAVMTNKMYRLVVE Mellp23 TPQHISNLHTAFLNTSSRFTSYNFREYFIRRSNLKFNDSIKELMVLERASVMNRLYKLVVE Mnele -------MYRVLMRTAQQFSDSAYRNYALRRIRHEFRRATDSLHMLTRQVTINRLYPDVLH Monbr ------------------------------------------------------------- Morel2 HRSQVLTLYKDLLHHSSKFAAYNFRDYAVRRTRDAFHKAEQQLEVVKRQSVISQLYKLVVE Mucci2 TSQKVLSLYRNFIRHGNKFSSYNFRDYTIRRSRDAFRKAEQELAVVKRQAAISQMYHLVVE Mydma NKMVVLRLYKNLLREGQNFGDYNFRSYATRRIRAAFKQADENFELIKRQANIGKMYRVAVE Neucr2 SAGKVLSLYRQLLRQGNQFSSYNFREYAKRRTRDAFRKGLQNLQMLKRQTVISQFYRLVVE Orpsp11 ------------------------------------------------------------- Pench1 TAFQARSLFRSLLRYSGQFSNYNFREYARRKTRDSFREGLQSLRLLKRQTIISQFYKLVVE Phybl2 SSAHVLSLYRNFIRFGNRFQSYNFKDYTIRRARDAFHKAEHDLEVVKRQAAISTLYRLVIE Picst3 TSRQVLLLYKQLLEKAYKFDNYNFREYAKRKIHDSFKSGIDSLAQLQRQTSISQMYKLVVE Plicr1 TRQALMSLYTNMLRTSRSFDSYNFRQYFVRKTKDTFKDAVKELAVLRRSAIVNQLYKLAVE Polpo TRQTVLQLYRSMQREANKFSSYNFREYSKRRIALGFRQSQNDYEMLKRQATINSLYKVVVE Pucgr2 QHQHIRTLEASFKAASNQFGSYNFREYFGRKSRQKFDASVDELAVIERASIMNRLFKLVVE Punst1 TPQALRSLYASTLRTARSFSSYNFREYFVRRTKDEWKNAVQELAVLRRSAIVNQLYKLVVE Rhior3 SSNQVLSLYRQFLRYGNKFASYNFRDYTIRRSRDGFRKAKYDLAALKRQATISQMYHLVVE Rhoto1 TRTHLLALYKEELRVAHSFASYNFKQYFLRRTRNKFRESLGELAVMARAAIVNKMYKLVVE Rozal11 ------------------------------------------------------------- Sacce1 TRRQVLSLYKEFIKNANQFNNYNFREYFLSKTRTTFREAKNDLGVLKRQSVISQMYRLVVE Salro MRSQALSLYRRMLREAQGFVSYNVRSYAVRRVREGFRKAKEDLEMLKRQRVVYQLY----- Schco3 SKHAILSLYHSTLRVSNSFSSYNFRNYFLKRARENFREAVKELAVLRRSAIVNQLYRLAVE Schpo1 SKQHVVRLYRNILKTSKLF-PYTYREYTIRRTRDKFKDSEKLLEIIQRQSIINGMYNLVVE Sorma SAGKVLSLYRQLLRQGNQFSSYNFREYAKRRTRDAFRKGLQNLQMLKRQTVISQFYRLVVE Sphar ------------------------------------------------------------- Spipu1 TKRQIISLYRDLIRSSRVFASHNYRDYIHRRAQDAFRRGKRDLEVARRQGWLNAQFKSVVD Sporo1 ------------------------------------------------------------- Stehi1 SSKSLLHLYMSTLRTARSFSSYNFREYFVKRTQSTFRDAVKELAVLRRSAIVNQLYKLVVE Tapde11 QSLQALSLYRSIIR-AAQPLPYNFRQYAKRRARDSFTAGLEDLRMLKRQGTIHGMFPLVVE Thetr ------------------------------------------------------------- Treme1 TVAAIQSLYASTRNTATRFASYNFHEYFVRRTDDMFKARRKELEVMERAATVSSMFKLVVE Trire2 LPQQTRSLYRQLLRQSKEFSSYNFREYAKRRTRDAFRKGLKELQMMKRQTVIGQFYRLVVE Umbra1 TKTQVISLYRQFLRSGSKFGAYNFRDYAIRRARDGFRKAEQELKVVQRQSTISSMFRLIIE Ustma22 SKSQILNLYRKYLRTSQSFSSYNFRTYFLRRSRDMFRTALEDLKVLQRSALMNRIYKLVVE Walse1 NRHHLLALYRALQRSATKFSSYNFRHYFLRRNRLAFREQRDQLDIVSRAAAVNRMFRLVVE Zygro1 TRTQVLGLYKQFIKNANNFNDYNFKNYFLRRTRASFRNALKDLGVLKRQSLISQMYKLVVE [Cluster3044.fasta_al_trimmed; alignment length = 44] Allma1 --GGKLKPL--KQAKSFEDESDAAFKAKQKEEQKKLAELGIKKS Ashgo11 RQGGKLKPL--KQKKKDVDDEDAAYKAKMKADAAAKKEMGIKKS Aspfu1 REGGKAKPL--KAPKKELDEEDLAFKERQRAEAKAKKELGIKKS Aurde31 RQGGKLKPL--KAPKKDEDDEDKAFKARHIRTADRMNPLGIKKS Batde5 -------------------------------------------- Botbo1 ---GKLKPL--KAPKKDEDEEDKAFKAKQKADAAALKDASVRDP Botci1 MGGNGTNPIHNKVKKKEDDEETIAFKLKQKEDKANQAKLGISGS Caeel RQGGKAKPL--KAAKKDLSEEDVEFKKKQQEEAKKIKEMGIKKS Canalb1 RQGGKAKPL--KAPKKDFDEDDAAFKAKQKADAAAKKAMGIKKS Cangl RQGGKAKPL--KQKKKDLDPEDQAFKEKQKADAAAKKAMGIKKS Capow -------------------------------------------- Catan2 RQGGKLKPL--KAPKKDMLDEDLDFKKKQMEEAKKIKELGIKKS Cioin RQGGKKKPL--KQPKKEMDDEDRAFKAKQKEEAKKLAEMGIKKS CocheC53 GQGAGTNPIHNKKPKKELDEDDIAYKNKLAADKKAREELGIKKS Coere1 -------------------------------------------- Conco1 RQGGKLKPL--KSGKKDLDEDDLAFKQKQREDAAKAKAMGIKKS Conpu1 RQGGKLKPL--KAPKKEDDEDEKAFKERKKAEEAALKAAEIRQE Copci -------------------------------------------- Croqu1 RQNGKAKPL--KAPKKEEDEDDKAFRDKQKADAAALKALGIKKS CryneH991 RQGGKAKPL--KAPKKDIDEDDLAFKEKQKKEAAELKALGLKKS Crypa2 RQGGKAKPL--KAPKKDLDDEDKAFLEKKKAEEKARKELGIKKS Debha1 RQGGKQKPL--KNPKKDEDEEDVAYKAKLKADAQAKKDMGIKKS Dekbr2 -------------------------------------------- Dicdi KDGGKKKPL--KAAKKEYDEEDIAFQNKQKEEAKALKAMGIKKS Dmel REGGKKKPL--KAPKKDLDEDDMAFKQKQKEQQKALEAAGIKKS Enthi -------------------------------------------- Falba REAGKKKPL--KAPKKDLDEDDIAFRNKQREEQKKIADLGIKKS Fomme1 RQGGKLKPL--KTAKKDEDEDDKAFKERKKAEAAALADAGIKKS Fusgr1 REGGKVKPL--KQAKKDLDEDDMAFLEKKRADEKARKELGIKKS Galma1 -------------------------------------------- Ganpr1 RQGGKLKPL--KQ---DVDEDDLEFKKKQQEEKKKLEEAGIKKS Gloin1 RQGGKLKPL--KQSKKDLDENDAEFKKKQQEEAKKLKELGIKKS Hisca1 REGGKAKPL--KAPKKELDEDEIAFREKQKADAKAKKELGIKKS Klula1 RQGGKLKPL--KQKKKDVDPEEEAYKEKQKADAAAKKAMGIKKS Lacbi2 RQAGKLKPL--KAPKKEEMEEDVAFKEKKKAEAEALKAAGIKKS Lenti61 RQGGKAKPL--KAPKKELDEDDVAFKERKKQEEAALKAAGIKKS Malgl1 -------------------------------------------- Mellp23 REAGKAKPL--KAAKKEEDEDDKAFKAKQKADAEALKALGIKKS Mnele RDGGKKKPL--KAPKKELDETDLAAKNKAKADAKALKEMGIKKS Monbr -------------------------------------------- Morel2 RAGGKAKPL--KAPKKELDEEDLAFQAKQKEEKAALKALGIKKS Mucci2 RQGGKLKPL--KKPKKFEDEEDLAFKKKKMEEAKKLKEMGIKKS Mydma -------------------------------------------- Neucr2 RAGGKAKPL--KAPKKELDEDDKAFLEKKRAEEKARKDLGIKKS Orpsp11 -------------------------------------------- Pench1 REGGKAKPL--KAAKKELDEDEIAHQAKIKADAKARKELGIKKS Phybl2 RQGGKLKPL--KAPKKDEDDEDLAFKKKQMEENKKLKEMGIKKS Picst3 -------------------------------------------- Plicr1 RQGGKLKPL--KAPKKEEDEDEKAFKEKKKAEAEALKAAGIKKS Polpo IQGGKKKPL--KAPKKELDEEDIAFQKKQQEEAKQLKEMGIKKS Pucgr2 RQAGKAKPL--KAPKKEEDEDDKAFKAKQKADAEAMKALGIKKS Punst1 RQGGKLKPL--KAPKKDEDEDDKAFKERKKQEQEAMKAAGIKKS Rhior3 RQGGKLKPL--KKPKKDLDEEDLAFKKKQQEEAKKLKELGIKKS Rhoto1 RQGGKLKPL--KAPKKEEDEDDAAFKAKQKAEAAKLKEMGIKKS Rozal11 RQGGKLKPL--KKPKKDLDEDDLEFMKKKKEQEAALKQLGIKKS Sacce1 RQGGKMKPL--KQKKKDLDPEDIAFKEKQKADAAAKKALGIKKS Salro -------------------------------------------- Schco3 RQGGKLKPL--KV---ALDEDDKAFLEKKKAEQAALKEAGIKK- Schpo1 -------------------------------------------- Sorma RAGGKAKPL--KAPKKDLDDEDKAFLERKRAEEKARKELGIKKS Sphar REGGKKKPL--KAKKKDLDDVDLEFKAKQKAA----KAA----- Spipu1 RQGGKLKPL--KAPKKDLDESDLAFKQKQKEEQAKLKSLGIKKS Sporo1 -------------------------------------------- Stehi1 RQGGKLKPL--KAPKKEVDEDEAAAKDKKKQEEAALKAAGIKKS Tapde11 -------------------------------------------- Thetr -------------------------------------------- Treme1 RQGGKAKPL--KAPKKEDDEEDAAFKAKQKAEAAAMKAAMISKL Trire2 REGGKAKPL--KAPKKDLDEDDLAYLEKKKADERARKEMGIKKS Umbra1 RQGGKLKPL--KAAKKDLDEEDLAFKKKQQEEAKKLKEMGIKKS Ustma22 RQGGKAKPL--KAPKKELDEDDLAFQRKQKEEEAAKKAAGKKK- Walse1 RQAGKAKPL--KAPKKDFDDEDIAFKAKQKAEE---KAKAIKKL Zygro1 RQGGKMKPL--KQKKKD-DEEGRAFKEKQKRDAQAKKELGIKKS [Cluster3046.fasta_al_trimmed; alignment length = 82] Allma1 EQQRRQLDRLMARADRP-LHLPVTNVQGSSAGAGSGDFHVYRAHRRRELARQKLIEEEFRAKRAAIENERTAKNRAKRMKRK Ashgo11 ---------------------------------------------------------------------------------- Aspfu1 SEQASQIEHLFRDPNKE-IKLPVANVQGSSAGAGSGEFHVYKASRRREYERLRLMQSAWEQKREEAREEKTEKNRRRREKRN Aurde31 EMQRAQLARLLKDPAKP-AFVPMKNVQGSSAGAGSGEFHVYKANRRREYERLKIMEEEFERKKREREEAKTAKNRAKRQKKK Batde5 DTQKAQVEKLMKRIDKE-IILPVRNIQGSSAGAGSGEFHVYRALRRKEYTRLKALDDEYESRQQTLKMEKTNKNREKRLKRK Botbo1 EVQRQQLAKLLKDPVKP-VVIPMKNVQGSSAGAGSGEFHVYKQNRRREYERLKLMDEEFEARKRQREEAKTAKNRAKRQKKK Botci1 SETASHIDKLMSTG------LPVQNVQGSSAGAGSGEFHVYKASRRREYERLKGMDEQWEREKKEREAEKTRKAREKREKKR Caeel DLIRMRLARLQQNIDKP-APIPVRNVVGSSAAAGSAEFHIYRNNRRKEQNRLDYIDAAYRHKVEKLEESKTAKKRAKRLRQK Canalb1 ---------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------- Capow DAQRRQLDALMKHPERE-IVLPIHHVAGSTAGAGSGEFHVYRNAKRREEARLRALDEEFHARAQQFKAAALAKKRSKRQRKK Catan2 DKQRQEVERLMKKPDQH-VNI-VTNIQGSSAGAGSGDFHVYRAHRRRELLRQRIMDEEHRAKMDAIKEERTAKRRAKRQKRK Cioin DIQKRKIEKLMANPEKP-VYIPVRDVMGSSAGAGSGEFHVYRHIRRREYNRQKFMSYEYMKKQEDNKEEATAKKRAKRLRKK CocheC53 TEQASQVEALFAKPDRE-IHIPVANVQGSSAGAGSGEFHVYKASRRREYERLRAMDEEFAKRKEELEKEKTEKNRLKREKAR Coere1 DKQRSHIDYLMRNIDKP-IELPVLNVRGSSAGAGSSDFSIYRDLRRKENLRIKHMDAEFEKEADALKEEKTAKKRAKRQKRR Conco1 DLQRIELEKLMKNPDKP-VNIP-KYISGSSAGAGSGDFHVYRASRRREYARQNLIDEEFELKIKEQLEKKTSKNRAKRLRRK Conpu1 EKQRSQLDRLLKDPSKP-AYVPMKNVQGSSAGAGSGEFHVYKASRRREYERLKMMEDEFERKRKEAEEAKTAKNRAKRQKKK Copci EKQRSQLERLLKDPAKP-AYIPMKNVQGSSAGAGSGEFHVYKAARRREYERLKLLEEEFERKRKEAENAKTAKNRAKRQKKK Croqu1 EKQRAQVARLLQDPTRE-IQLPMKNVQGSSAGAGSGEFHVYKQSRRREYERLRLMDEEFETKQAELKESKTNKNRARRQKRK CryneH991 DMQRRQLEKLLANPDKE-VTLPMKNVQGSSAGAGSGEFHVYKQSRRREYERIRLMTEEFLKRQAERDEAKTAKNRAKRQKRK Crypa2 ---------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------- Dicdi SVTST-----------------VAHVSSSTAGSSSGDFHVYRNLRRKETLRLEEMDKEFSERREQQKELKVKKKAEQRKKNK Dmel ---------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------- Falba DAKRAELQRLMSKEN---PQLPKIDVSGSSAGSGSGDFHTYRVERRRELERQAFVLHRLAEQDSQWQEDRTNKNRQKRERQK Fomme1 ---------------------------------------------------------------------------------- Fusgr1 SAQAASVEALFLKPDQN-IRIPVTNVQGSSAGAGSGEFHVYKASRRREYERLRSMDEEFSKDKSERDEERTRKNREKREKMK Galma1 EKQRSQLEKLLKDPAKP-AYIPMKNVQGSSAGAGSGEFHVYKASRRREYERLKLLEEEFEKRRRETENAKTAKNRAKRQKKK Ganpr1 EAQRVKLENLFRRIEKP-INLPVRNIPGSSAGAGSGEFHIYRHLRRKEMARVERMDEQYAERQAFLREERTAKRRAKRKKRK Gloin1 EIQRQQLEKLLKRVDKP-VNIPVRNVQGSSAGAGSGEFHVYRAHRRREYTRLKVMEE------------------------- Hisca1 SEQATQIQSLFKDPSKD-IRIPVANVQGSSAGAGSGEFHVYKASRRREYERLKLIEEMFERRREEAREEKTEKNRRRREKKK Klula1 ---------------------------------------------------------------------------------- Lacbi2 EKQRYQLEKLLKDPAKP-AYVPMKNVQGSSAGAGSGEFHVYKASRRREYERLKMLEEEFERKKREAENAKTAKNRAKRQKKK Lenti61 DKQRAQLEKLLKDPAKP-AYVPMKNVQGSSAGAGSGEFHVYKASRRREYERLKMMEEEFERKKREWEEAKTAKNRAKRQKKK Malgl1 EKQAQNIEQLFDDPKKA-LRMPVNHVQGSSAGVGSGEFHVYKMSRRNESERIEAMKYEFDKKRDEQANAKTSKNRARREKKK Mellp23 EKQRAQVARLLQDPTRE-IQLPMKNVQGSSAGAGSGEFHVYKQARRREYERLRQMDE----KASELKESKTNKNRARRQKRK Mnele DKQRRKLDNLMARIDKP-LNIPVRNVMGSSAGAGSGEFHVYRAIRKRTMQREEFLTKEFNKRVAENREAKTAKKRLKRQKRK Monbr ERLRWQVNKLMEHPERE-YELPNPNIHGSTAGAGSGEFHVYRAERRREERRQEYIDSAFSVKEAALKDRKTSKNRAKRQKAK Morel2 ELQKKQLDKLLEKIEKP-VRIPVKNIQGSSAGAGSGDFHVYRAGRRREYARLKQMDEEYEEKIQAKKEEKTEKNRNKRQRRK Mucci2 EEQQEKLNRLFQKIDKP-VYIPVRNVSGSSAGAGSGDFHVYRAQRRREYARMKNMDDEYSEKLRRLREERTAKKRAKRQKRN Mydma DIQRRKIDKLMSDPTKE-PYIPVRHVMGSSAGAGSGEFHVYRGIRRREARRNEYLDKEFKKKLIENENKTTEKKRLKRQKKK Neucr2 SLQASHLQQLFAKPDRE-IIIPVTNVQGSSAGAGSGEFHVYKAARRREYERLRIMDEEFEAKKREREEEKTRRNREKRDK-- Orpsp11 EIQKVQIENLMKRIDKP-IILPIRNIQGSSAGAGSGEFHVYRALRRKELTRIKLMEE------------------------- Pench1 SEVASEIQTLFKDPSKD-IQLPVTNVQGSSAGAGSGEFHVYKASRRREYERLRLMQSAWQKEQEEKKDEKTEKNRRRREKKK Phybl2 ELQQQQLEKLFKKIDKP-VFIPVRNVPGSSAGAGSGDFHVYRAHRRREYARLKEMDEEYEMKIAQLKDERTAKKRAKRQKRK Picst3 ---------------------------------------------------------------------------------- Plicr1 ERQRSQLEKLLKDPTKP-AYVPMKNVQGSSAGAGSGEFHVYKASRRREYERLKLLDEEFERKRKEAEEAKTSKNRAKRQKKK Polpo -----------------------SNVSGSTAGSGSGDFHVYRNQRRKELTRLEKLEKEFQERREDKIEERTAK---KSQKRK Pucgr2 EKQRAEVAKLLQNPARE-IHLPMKNVQGSSAGAGSGEFHVYKQSRRREYERLRLMDEEFENKQAEIKEAKTNKNRLKRQKKK Punst1 DKQRAQLERLLKDPAKP-AYIPMKNVQGSSAGAGSGEFHVYKASRRREYERLKMLEEEFERKKREREAAKTNKNRAKRQKKK Rhior3 QIQQKELEKLFEKIDKP-VQIPVRNVSGSSAGAGSGDFHVYRAQRRREYARMKNMEDEYKNRLARLREERTAKRRAKRQKRN Rhoto1 EQQAAALNKLLSNPDRE-VRIPMKNVQGSSAGAGSGDFHVYKQSRRREYERLKLMDEEALERQRAAEEEKTAKNRLKRQRKK Rozal11 TVHKRQIEKMIAHPEKP-----FQELD-LTGGVGVGR---YKKNRRDEYLRLKAIEDEFDRKRELTLDEKTSKKRAKREKKK Sacce1 ---------------------------------------------------------------------------------- Salro DKQRWEINKLLANPDRR-SEIKNSNISSSTAGAGSGEFHVYRHNKRRELSRLEYIEALFKLKMQAAQNAKTSKNRKKRQRAK Schco3 EKQRAQLERLLKDPAKP-VYVPMKNVQGSSAGAGSGEFHVYKASRRREYERLKLLEEEFERKRKAVEEAKTAKNRAKRQKKK Schpo1 ---------------------------------------------------------------------------------- Sorma SLQASHLQQLFAKPDRE-IIIPVTNVQGSSAGAGSGEFHVYKAARRREYERLRIMDEEFERKRVEREEEKTRRNREKREK-- Sphar SIFNSTFLCLSAQIDKP-LNIPFRNVMGSTAGAGSGEFHVFRATRRHEYARSAYYDAAFAEKRMREEQKAAEKRRAKRQKKK Spipu1 EAQAARIERLMTRVDKP-IALPVRNVQGSSAGAGSGEFHVYRALRRKEYARQKILDEEFHEKLEAIKAEKTAKKREKRQKRK Sporo1 ---------------------------------------------------------------------------------- Stehi1 EKQRSQLDRLLKDPSKP-AYIPMKNVQGSSAGAGSGEFHVYKAGRRREYERLKAMDEEFAERKRQREDSKTAKNRAKRQKKK Tapde11 SIQRQQLEYLESHPDRDHTAVPVSSTQGSSAGAGSGEFHVYKASRRRELERLAEMDAAFERNRERTREERTEKNRLKREKQR Thetr ---------------------------------------------------------------------------------- Treme1 DMQRYHVEKLLAKPDQE-VALPVKNVQGSSSGAGSGEFHVYKHQRKKEAERIKLMDEAFVARQAERNEAKTAKNRAKRQKRK Trire2 SAQAASLDALFAKPDQE-IRIPVTNVQGSSAGAGSGEFHVYKAARRREYERLREMDEEFEKSRAEKLEEKTRKNREKREKAK Umbra1 EQQQRQLQKLFERVDKP-IVLPVRNVQGSSAGAGSGEFHVYRALRRKEYTRLKDMDE---------------AKRSKNMPRN Ustma22 ERQAHAISKLLANPDKE-IRIPMKNVSGSSAGAGSGEFHIYKHQRRREYERIQLMEEEFDRKRAQAQEAKTDKNRAKREKKK Walse1 DYQKEQLDKLLEDPTKP-VYIPFAHVQGSSAGAGSGEFHVYKQSRRREYDRVQLMEEEFEQRRREREEAKTSKNRNRRNKRK Zygro1 ---------------------------------------------------------------------------------- [Cluster3047.fasta_al_trimmed; alignment length = 45] Allma1 G-ILLECDSTVKQIVLMLNEFVL-EDLDDTHLFLVVRSTINAQLD Ashgo11 G-ALVQCDPSIRALILQIDSIIW-EELDETH-LLVIKEKLNWFLS Aspfu1 G-VLIECDPSVKAIILKYDEYIV-EDLDDDRHLVILKERLGRELD Aurde31 G-VMLTCDSAVKQLLVMMDDFII-QDLDENH-VLIVRQELEQELE Batde5 --YLFTSDQAVKQIIKELDSFII-EDLDDTH-LFIVQDRLEDILE Botbo1 G-VLVTCDAAVKQILLHMNTFII-QDLDDTH-LVIIRRALDVELE Botci1 G-TLVECDPSIKSLIVKIDAYIV-EDLDDET-LLILKALLEKALK Caeel G-VLVTSDPAFRQLLIHLDDFIV-RELDDTH-LFILENKVEQIME Canalb1 G-VLVQCDPSIKALIIQIDSIIL-EELDETH-LLIVKSELNRLLS Cangl G-VLLKCDPSIKALIVQIDSIIL-EELDETH-LLVIKMELNRLLS Capow G-VLIECDAAIKQFLLHLDSFII-ADVDETH-LFVLQTKLDEMLD Catan2 --------------------------------------------- Cioin --------------------------------------------- CocheC53 G-TLVKCDASIKAMLVDIDSYII-EELDEEH-ILVLKARLNQMMR Coere1 G-TFIECDSAAREVLLKLNSFII-EDLDSTH-LFIIQVVLDELMD Conco1 --------------------------------------------- Conpu1 --------------------------------------------- Copci G-VLLTCDPAVKQILLAMNEFII-EDLDDYH-LVIVRRELEAELE Croqu1 G-VLLTCDPAVKQLILSLNDFIV-QDLDETH-LLVLRVELEAELE CryneH991 G-VLVTCDSAAKQILLHLDSFVI-RDVDENR-VMIIKDELQTELE Crypa2 G-VLVQCDASIKSIIVSIDNYVI-EVLDDQN-IVVLKELLEDRLK Debha1 G-VMVQCDPSIKALILKIDSIVI-EELDETH-LVIVKNELNRLLS Dekbr2 G-SLVQCDPSIKALIVNIDAIVI-EELDDTH-LLVIKRELNILLS Dicdi G-LFLECDPPTKQFVEYISKVIV---LDETH-LFLIQRRIDDLQN Dmel G-VLVECDPAMKQFLLHLDEFII-QDLDENH-LFILQARVDDLMD Enthi --------------------------------------------- Falba --------------------------------------------- Fomme1 G-VLLTCDAAVKQILLTLNEFIV-DDLDDFH-VVIVRRQLEAELE Fusgr1 G-VLIECDPSIKSIIVSIDSYII-EDLDDER-VVVLKAKLEDRLK Galma1 -----TSDPAVKQILLLLNEFII-EDLDEYH-IVIVRRELEAELE Ganpr1 --------------------------------------------- Gloin1 G-VIIKCDSTVKQVIYKLNEIII-EDLDDTH-LFIVKIEVEKLLE Hisca1 G-VLIECDPSVKAIILKYDQYIV-EDLDDERHLVILKARLSNELD Klula1 G-TLVQCDPSIRALILRMDAIIY-EELDDTH-LLVIKYELNRLLS Lacbi2 S-LILTSDPAVKQILLSMNEFII-EDLDDHH-LVIVRKELETELE Lenti61 G-VLLTCDSAVKQILLTMNEFII-EDLDDFH-VVIVRRELEAELE Malgl1 --------------------------------------------- Mellp23 G-VLLTCDPAVKQLILSLNDFIV-QDLDDTH-LLVLRAEIETEVR Mnele --------------------------------------------- Monbr --------------------------------------------- Morel2 G-TIIECDTSVKQIIIGLNEFII-EDLDDTH-VYILRHDIDEILN Mucci2 G-VLLECDSTVKQIVLNLNKFVI-EDLDDTH-LFILKYELDKILD Mydma --------------------------------------------- Neucr2 G-VLIQCEPAIKSIIVHLDSIII-EDLDEQT-LVVLKQKLEDRLK Orpsp11 --------------------------------------------- Pench1 G-LLIECDPSIKSMILKYDEYIV-EDLDDENHLVILKVR----LD Phybl2 G-VLVECDSTVKQIVLNLNKFVI-EDLDETH-LFILRYELDKVLD Picst3 --------------------------------------------- Plicr1 G-VLLTCDSAVKQILLSMNEFII-EDLDDFH-VLIVRRELDAELE Polpo --------------------------------------------- Pucgr2 G-VLVTCDPAAKQLILKLNDFII-QELDDTH-LMVLKKQLEAELE Punst1 G-VLLTCDSAVKQILLTMNEFII-EDLDDFH-VVIVRRELETELE Rhior3 ------------MIVLNLNKFVI-EDLDDTH-LFILKYELDKILD Rhoto1 G-VLVTCDPAVKQILLQLDEFII-ADLDETH-VLIVKDELEEALE Rozal11 --------------------------------------------- Sacce1 G-ALVQCDPSIKALILQIDAIVL-EELDDTH-LLVVKHELNRLLS Salro G-IVLRCDMSIKTFVQALEAFII-EDLGSFG-LFVIEGRVASMLD Schco3 G-VLLTCDPAVKQILLILNEFII-EDLDDWH-IVIVRRELEAELE Schpo1 GLLLVECDPTVKQLILNMDEIVI-EEIDEER-LLVVKAELERRLE Sorma G-VLIQCEPAIKSIIVHLDSIII-EDLDEQT-LVVLKQKLEDRLK Sphar G-MLVECDAAMKEYLIWVNEFIINSELDETH-ILIVKSKMDYLMN Spipu1 --------------------------------------------- Sporo1 --------------------------------------------- Stehi1 ----LCSDSAVKQILLTMNEFII-EDLDDFH-IVIVRRELEAELE Tapde11 --------------------------------------------- Thetr GTLLVCADSAVKQFVLSLDVWVL-ADLDDVH-LVVIRNKLRDLLD Treme1 G-VLITCDSAAKQILLHIDSFIL-RDIDETH-VLVMKDLLQVEV- Trire2 G-VLIECDPSIKSIIVNIDSFII-EDLDEER-VVVLKQKLEDRLK Umbra1 G-VLIECDTTVKAIIKNLDSFIV-DDLDDTH-VFILKSELERLLD Ustma22 G-MLLTCDAAVKQLILSLDEFII-MDLDETH-LLILRAELEVELE Walse1 -------DPAVKQIILNLNDFIV-QDLDLQH-ILVIKYELENEVC Zygro1 G-ALIQCDPSIKALIVQIDAIIL-EELDDTH-LLIIKRELNRLLS [Cluster3069.fasta_al_trimmed; alignment length = 122] Allma1 MSSKRPVSRKRQVVRDPRFFKKSYSFIDEYKERELAELKQTLESTRLIQTIQAIENRERELQQKIKREWRKSEVEKIKQ--GKPFFLKKSEERRLQLISKFELEKMAEKKRKRDAGKDRKFM Ashgo11 -------------------------------------------------------------------------------------------------------------------------- Aspfu1 QSSKHPVTRKRTIIRDPRFSQSAYAFLDDYRAAELKEMKEKLQKEALKRDIRSATDENRRREKEVLAEHKKREKELIRE--GKPYFLKKSELKKQALLKKYQRVKALERRQKKLTAKERKEM Aurde31 VTSKKPVGRFRPVVRDPRFFQQAYSFLPELHVQELSTLKENLEVQRLELAVRRLESHRQKVEQAALDTAMKAEKEKQKQ--GKQWFMKNSEKKSVILKARYAVQKAIEKKQRKIAQKEKKSR Batde5 ITSKRPVTRKRRVVRDPRFFKRSYGFIDDYERSEIAMLKDEIRRAQLQKTMTSKVSEIKEKTQKLKREWRKTESAKVQQ--GKPFFLKNSELKRRQLVDKFDLDKVLEKRRKKNASREHRHI Botbo1 MSSKRPVTRRRAVVRDPRFFDSSYGFLSDIQKSEVSTLRGALEVTRLERALKRSESERERRNQEVLKRAKKEELSKRTE--GKQWHMKDSEKRALLLKGKFAVKKAIEKKKKKVSQKEKKSR Botci1 VSSKKAVSRRREVVRDPRFIEKNYDFLVDYREDEMKKLKETIEKEKLKRELLRMESARKRKAREVLDKHRKEEKELVKE--GKPYYLKKAEQKKRVLLDTFQLDRVIERRRKKVEGKEKKNM Caeel -------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------- Capow VSSKKRVDTLRNVVRDPRFFEKSYGFVNEMKTREMKEVSAAARLEEIKSTLARMKQEQERQRRHFKAERNRQERDLVKQ--GKPFFLKKSDERKLEAVQRFQLNKFLEKKRRRNAAKDHTSV Catan2 MTSKRPVSRFREAVRDPRFFDKAYGFVYDLRSQEIHQLKQQLQAQQLMRTIQAMENKEAKVKQRIKRDWRKQELDKVKE--GKPFFLKQSEQKKLYLINKLELDKVAEKKRKRDAGKDWKWM Cioin ISSKIKVPKMRQVVRDPRFFNNRYQFLDNIKQREKLNLKKQVDQQQLKYLLSRMEQKQRMEKREEERKWKKEEMKKVKQ--GIPYYLKNSTKNKMVAELR-ASNKSEIRKEKRQKSRESKVM CocheC53 QSSKRMVSRKRQVVRDPRFIDKRYSFLNDYRASEISELRSTIEKERLKKKLLSMESENKEKLKEVTREHKKKEKELVKE--GKPFFLKKSEQKKIALVDRFQRDKVIERRRKKVTAKERRNM Coere1 MSSKRPVGRFRQVVRDPRFFEKSYEFLEKQQQEEMDELRKQAEARRIQKALGSMQSQQKKHMQELKRTHRKMESEAVKQ--GKPYFLGRRDLKDLEVAQKFKLDKFLEKRRKRNATKDHRRM Conco1 MSSKKPVSRLRQIVRDPRFFKKSYSFVEDMKNEELKDLKKSVLKNQLKQQLETELAKQKEDKQKLKRELRKNEMKLIKD--GKPFFLKKSDMKQIELTQKFNIDKLLEKRRKRNANKDHKAL Conpu1 -------------------------------------------------------------------------------------------------------------------------- Copci VTSKKPVSRKRTVVRDPRFFQKSYGFLAESRKEELKTLKETLEIERLERAVKRTESRMDAIQQQALQRVKKEEKEKQKQ--GKKWFLKQCEYQRAFLSG-Y----------KTKGGTKGSLR Croqu1 MSSKRSVTRKRTVVRDPRFHQRSYGFLRSQRKAELDELRQAFELRRMEDALKRAENEKLEQEREALKKWKASEKVKQQE--GKAFYLKKKDQKDVILADRFKLQKAMERKRKKVAGKEKKSM CryneH991 MSTKKQVSRKRQVIRDPRFHSKSYSFLPDLLRQEFSGLKEAVERERLEVQMGQVRTEKESMEREILAKAKKEEREKRTQ--GKAWYMKKGEKKDLLLKARFAVKKLVEKKRKKLASKEKKSR Crypa2 MTSKRQVSRKREIIRDPRFARKAYAFLDEYRDDEMRQLKTAVEKEKLQRTLMSMESDRKDKERAVVEEHRRREKELVKE--GKPFYLKKSEQKKQLLVNQFQREKAIEKKRKKHTAST---- Debha1 -------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------- Dicdi MTAMKPVSRFRQVVRDPRFYRKRYGFLDDVIKRDVERMESTWERDQLYKKIQSKKSQLKDQKRETKNKLWSNEIESVKK--GKPYHISNKTVKQFELQEKFKLDKFMETKRKRISSKEKTFL Dmel -------------------------------------------------------------------------------------------------------------------------- Enthi VSAKKKVSRTIEIFRDPRFFCKKYKFLEEKQKEEANELSKQIEREKLIKKRQQLNQKKYKNEEIIKRGLVEENHKRIIE--GKPKFLSKQELKEEVDKQTYQLKKVEEKRIKRESGKLMKRA Falba QSSRVRVSVLRQVVRDPRFFKKAYGFITDQRQQEIDKLRASIRREGLKMSLQRLTQKDDDKKQAVRSERLSKERELVRQ--GKPYFLKKSDERKIATAARFAVQKVLERRRQKQAAKDRRFL Fomme1 MTSKRAVTRRRQVVRDPRFFRKNYSFLEDIHKNEYDALKENVELDRLERAFKRAESRREAVERQALEKAHKEEKERRKS--GKEWHMKKSAKKELLLKARHAVRKAIEKRQKKISQKEKRQR Fusgr1 QTSKKPVSRRREIIRDPRFASKAYAFLDEYRDKEMADLRVQIEKENLKRQLQSMESVRRQEEENLLKEHRKKEKELVAQ--GKPFYLKRSEQKKQLLVNRYQVDRAIERKRKKVAGKEKKEL Galma1 VTSKRPVTRRRTVVRDPRFFHTQYSFLADNHRKELSTLRETLEVYRLEQAIKRAESRLDRVQRETLSKAKKEEQQKRTQ--GKEWYLKKGEKQKLIMEARYAVKKVIEKRQKKQSQKEKRSR Ganpr1 LPSNRPVSRMRKVVLDPRFVRKSYAFVEEARKGELAQLKKAAEKDKLKRAVESLENEAQRRREDIRREWRKKQEDRVKK--GGPFFLKKSDLKRIEAVEKFKVDRYLEKRRKKNRGKERVKV Gloin1 MSSKRPVSRFRQIVRDPRFYEKTYSFLNEYKKSEIEQIKSQIEKSRLQQLLSKLQSKNIKRKKELKHERKKREVELVYK--GKPYYYKKSDVKKLELIDKFVLEKVIEKRRKKNASIKHKYI Hisca1 QSSRHAVSRKRTIIRDPRFARNNYAFLNHYRTDEIAELRKQVEIVRLKREITSMSDERKEMEREVLVQHRRREKELIRE--GKPYFLKKGEVKKEVIAKRFEKQRALERRRKKVVGKERKEM Klula1 -------------------------------------------------------------------------------------------------------------------------- Lacbi2 VTSKRPVTRRRTVVRDPRFFQKQYAFLTDAHKTELRTLRENLEVYRLEQAVKRTESRLDQVLREALGKATKEEKTKRKQ--GKGWWMKESDKRELLTQARYAVKKAIEKKQKKVSQKEKKSR Lenti61 MSSRRPVPRARLVGRDPRFFQTQYGFLSTMHVDELKTLRENLEVERLERAVKRAESRREKVEMDALSKAAKEEREKQNQ--GKAWYMKDADKKALLLRAKYAVRKAIEKKQKKVNQKEKKKR Malgl1 MSSRRPVSRLRQVVRDPRFHAKSYGFLPDLYQTEIKQLRDQHQRAHVEQELRRAESTRRERERSVKADFKKENQRRVDA--GLPFFPKKAQFQEALLRKQFSLRKAMDRKRRKDAQKEKKSL Mellp23 -------------------------------------------------------------------------------------------------------------------------- Mnele MSSKRKVSVIRELKRDPRFFQDSYGFIKEIRSEEKSQLQAELKRDQLVRLINKMNTQVKSERQRLKVESRKRAMHNVKE--GKPYFAKKSELRKSELKNKFKVDKYLAKRRKLNLQKDKKSL Monbr VSSKRRPRGVRQVVRDPRFFDRNYEFLEEKQQQELDTVRQELRQEQVKRLLQSLRNKRTARERDHARRQAMHQAGLIDQETGLKYHLKKSTQRQLDLLAQYQLNKAMKTRRKHRVAKLKKSF Morel2 VGSKKPVGRFRQVVRDPRFFEKSYSFLKDYQADEMKKLKELIMKDKLQNQLSRMIDAAQKRRQEIKRDHKRKEKELVLK--GKPFFLKKSDQKKLELIDKFALARAMEKRRKRNSAKEKTKI Mucci2 ISSKRAVGRHRDVVRDPRFFEKSYNFLNDYKKSEMEMLKESIKQEHMKGLLLKMVSQERKRKQALLRERKKQESELVKQ--GKPYFLKRSEKRKLDLMDRYSVDRILEKRRKRNTTKDRKHL Mydma -------------------------------------------------------------------------------------------------------------------------- Neucr2 TTSKKPVSRRRDFLRDPRFARKAYSFLDDYQEDEMKQLRMAIEKEELQRALLSMESARKDKERELLSEHKKKEKELIKQ--GKPFYLKKSEQKKQLLVEQFQVDKAIERKRKKIAGKEKKAL Orpsp11 ISSKKPVSRYREVVRDPRFFKKSYKFLSEMEENEMNMIQEKIEKEKLSRVYQSLKSEAKERRQAIKREWRKKEMQRVKE--GKPYFLKKGK------------------------------- Pench1 LSSKRAVTRKRTAVRDPRFGGKAYAFLDEYRASELNDLKEQMQKEKLKGEIRRMQDQNKKREAEVQAEHKKREKQLIRE--GKPYYLKNSELQKQVLERKYERAKALERRRRKMASKERKEM Phybl2 MSSKRAVGRFREVVRDPRFFEKSYDFLDDYKQNEQAMLRDRITRAELESALIRMVSKEAKRKQLLARERKKVEAELVEQ--GKPFYLKRSEKRKLDLVDRYNMDKILEKRRKRNATKDHRRV Picst3 -------------------------------------------------------------------------------------------------------------------------- Plicr1 VTSKRPVTRRRQVVRDPRFFQNQYGFLADLHSNELKALRENLEVNRLDMAVKRAESKREKVEREALSRVEKEEHEKRKQ--GKGWWMKDSDKKDLLVRARYAVKKAIEKKQKKIGQKEKKSR Polpo TTAKVPVSRYKQ-VRDPRFYREKYGFLDDIVKKDINKLSERLLQARITREIQSKRSDLQDKRRKLKEEWQKQEVENVRQ--GKPFYLKQSALKDLEIKDKFQLDKYMEKRRKKVSSKSKLNL Pucgr2 ISSKKPVTRKRTIVRDPRFHERSFEFLKEQRKSELEQLRQTLQLEALENHIRKEENQKLMWEKQALKEWKSQENAKRKE--GKAFYLKRKAQKEIILTNRYKLHKSIEKKRKKVDGKEKKSM Punst1 ITSKKPVTRRRTVVRDPRFFRKQYDFLAELHEQEHKELRENLEVKNLEAALKRAESKRERVEHAALEKVSREEKERRKS--GKAWYMKNADKRELLTKARYAVKRAIEKRQKKVSQKEKKSR Rhior3 -------------------------------------------------------------------------------------------------------------------------- Rhoto1 MSTKKPVSRVRQVVRDPRFFKKSYSFLADQQKAELETMRKTAEKDKIEEALKRMENRNKEREEEALQQWKKGEADKRKE--GKAFYLKDTEKKKLFLKAKFKLHKAIDKKRRKTAQKEKKLM Rozal11 ISCKRPVSVIRN--YDPRFFKKSYGFVNDLRRQEMKKLEDQVVKEKAKELLLSLES-----KKDVLKQHRKKEIELVKH--GKPFYLKKSDQKKLLMAEKFAIDKYIEKKRKKNASKKRKEL Sacce1 -------------------------------------------------------------------------------------------------------------------------- Salro MSSKKRPPAVRRVIRDPRFFQQAYGFLDEKRKAEMKQIQKRLRKQELQRLLQSMKEEQKARQREAKVKRNKM----VKD--SKKYFLKKSDQKKLELLSKFKLDKALKNRRKHNLQKDKAAV Schco3 MSSKKPVTRRRQVVRDPRFFKQSYSFLADMHRNEFTTLRENLEVETLERALKKAESKREAIEQQALERAAKEERERRAK--GKEWYMKKGEKREMLAKARYAVSKAIDKKRKKIAQKEKKAR Schpo1 KVDKKFLAKERNTPVFAKFVKKNYGFLNEYRVSEIQQLRDELRAESIRQTLKSLLSLEEERAERVMHEFRAQEKERVKE--GKPFYLKRNEQKKLIQMDKYALDKYIEKKRRRRAQKEKKHL Sorma MTSKKPVSRRREFLRDPRFARKAYSFLDDYQEDEMKQLRMAIEKEELQRALLSMESVRKDKERELLSEHKKKEKELIKQ--GKPFYLKKSEQKKQLLVEQFQVDKAIERKRKKIAGKEKKAL Sphar MSSKTTVTRLRKVVRDPRFWQKAYGFLDEYRAEELKELQAQFKREEIQLTISKIKQRREKAKQELKAKFRKAEEAAVAK--GKPFYLKKTEQKKLEMVAKFELDRYLEKRKKKNTSKDHRYV Spipu1 VTSKRAVTRRREVVRDPRFFQQSYGFIRDYEQHEVEMLKKRIVKEQLHKTLTSMQSKQKDKRKEILRNWRKTEEDLVKL--GKPWQLKKSDIKKLELVEKYDVDKLLEKRRKKNAAKERRFL Sporo1 MSTKRPVSRARQIVRDPRFFNRSYSFLSGSLEKEVETLRKTAEKEKIEDSLRRMENKRKEREQGALKEWKKEEKEKRQQ--GKAFYLKEADKKKLFLKAKFKLSKAMDKKRRKTSQKEKKQM Stehi1 VTSKRPVSRRRTVVRDPRFFRNQYGFIADMHETELKTLRDNLEVQRLELAVKRAESRREKVEQEAMNRAMQQEKAKQKE--GKQYWLKDGAKKELMLKARYAVRKVIEKRQKKAAQKETKSR Tapde11 -------------------------------------------------------------------------------------------------------------------------- Thetr MSAK---TKPRGLPRDPRFWYARYKHIREQQDVEMGQLRKSLARAELRDQLRKVQARRAKARRNI--ERKRMEAALVAQ--GKPYHLKNKDRKKLDLAIKFNLNKYVKRKRKKNLARDRKRM Treme1 MSTKRQVSRIRKVVRDPRFHSKSYDFLPDLLKDEMAILRTALERERIERDLGQLRTQREARERQVLAEVKREEREKREK--GKAWYLKKSEKRDLLLKSRYRVKKVLEKKRKKVAQKEKKSR Trire2 MTSKKPVSRRREILRDPRFFAKNYAFLDEYREKEMADLRAQIAKEELKRQLLSMESQKKEEEARLLQEHRKKEKELVAQ--GKPFYLRKSEQKKQLLLNRYQVDRAIERKRKKVASKEKKEL Umbra1 MSSKRAVGRYRDVVRDPRFFEKSYGFLDKYKQDEEQMLKAQMEKLKLQNILMRMVSTEAKRKQSIKRERKRTEQELVKE--GKPFYLKKSDQKKLELIDKFNVDKILEKRRKRNATKDHKKV Ustma22 ISSKRPVSRRRNVIRDPRFFAKSYSFLPEMFKDELGTLKKTLERAKVEAALRRAEGERRARESAVKGKIKSQNKERVEK--GLPFYPKKSEIKQMLLKDKYQLKKALERRRKKNAQKEKRDM Walse1 VTSKRPTSRKREVVRDPRFFEKSFSFLKGSLSKEVAEAKEQLEVDRLTHEIQRMSSQKKDIEKEALRKIKKEERDKRGE--GKAYYLKDSEKRKRVEEAQKAVKKSEERKRKRHEGKEKKSL Zygro1 -------------------------------------------------------------------------------------------------------------------------- [Cluster3081.fasta_al_trimmed; alignment length = 269] Allma1 IGRNLVAYLIRVVDKTAWLNDAHKAAIEVEFRQANLVASIERAFWDYVINLAAETKYSQSDSVYEEKVFVLSVNCAKEAA--KQKCKYVEVSTGQVYDKKSSDEKAEEEIKKIPDLNLIIVRPAIVYGPLIIGHIYKHLKEEMKFLWTKDLNTVHVEDVCRALWALCV-FNLVDKQDTDQETINRHIRSIFGIQTGFQG-SVTEEVNDTHMAPWSDLLKASS-PLTPYLDQLLYNNSLSMDGTKIEKVVGFSVTEQHIRDIVDGYKKQG Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 IGRHLALYIVRLVDKLAWLAPEFEEACSDKFVQADASQHFPRIFFDYVINCGGETRHSQPDDVYELRSYNLTVALGREVA--RRGIRFVECSTAHVYGSSPRKEKASDELKKIPGLNYCLLRLPHVYGEICLARVHLDMETDLELLYTKNLNTLYVKDAASALWKAAA-FNVVDHGDTRQEHVAEALSTVFGLKTSFLG-DVVDDMNEVSLQGWAELLEKKG-PISPFLEKVIKDQDMSIDGTLFEKTTGWKFDAEGVRAMVDSYKRMG Aurde31 FSRAIAHYLLRIVDKTTFVGHEFPKLLGVVYQQINLTANVTKAFFSIVFDCTGDITFDRHDEHQHMNTAALAYGLGQEAA--RRKVAYVRLQPP-YYDKPAHTEEALRLLAGISDLNLAIVRVGSVYGPLILGAVYKKAQEEFRFLYPANRNTVHTDDVAGAVWAVAF-FNLVDDTDATQGGIAALVADIFGIKTGTYN-DVASQANEAHSSTWMQIISEST-PLTAYLDPLFGKRAISYNGSKIKNVVGYQITREAIQEVLNSYKSDG Batde5 IGRNLVSLLIRVVDKTAYLSDAHKKVFAVEFKQANLVASAEKAFFDIVFNLAAETKYGQAEEVYDEKVYQLSMAVGKEAA--KRGIKFVEISTAQIYGKKPSAEKAEEELKKLAGLNLIIARPAIVYGPLIIGAVYKHLKEEMTLLWTKDLNTVHVRDVARALWHMAT-YNIVDKNDTDQGIVNKHIESIFGIKTGFQG-SVTEDVNDKHLQPWSELCKTGT-PLTPYLDKLLKDNSLSIEGIKIEKELEFKMTEQLLREVIDGFIAQG Botbo1 CSRALASFLLRIVDKTTYLGRQFSNTLKVDYKQANLIATVKQVFYSYVFDFTGEIQYDRTDPVQIKNTTQLGYSLGVEAA--KRKVAYVRLQHP-FYEKRVSDEETLRALAAIKDLNLVIVRPGSIYGPIIMGAVYKYLDEEMKYLYVLTHNTVHVDDVSRALWAVAL-FNLVDDSDSTQSSMGQVIANVFGIKFGFHG-EMIGDVNEKHMEAWTMLIHKST-PLTAYVEAMLAKYSVAYAGKKIKEVVGFEFDEDAVREVVGSFREEG Botci1 IGRFLALHIVRIVDKLAWLAPEFEDACSTKFMQADASQSLPRIFWDYVFNCGGETRYSQEDEVYKVRSLALSIAVGKEAA--KRGVKFVELSTGMVYDSTPSKEQAEEALAEIDGLNLIIVRLAHVYGDLTMARIYQHLDEEMKFLWTKDLNTVNINDTCRALWAVAT-FNVVDKGETSQKTMAELIGQIFGIKTGFQG-SVVDDINEEVLGPWADLLEEAG-PLTPFMEKLLKDTDLSMDGSRIEKVVGFTITKELLQGMIDSYIRIG Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow IGRNLIVHLIRVVDKTAWLTERQTKAFAVEFVQGNLTASTANAFFDFVINLAAETKYGQTEKIYEEKVLSLSVCVAKEAA--KRGVKFIEVSTAQVYDKDASTEKAEEAIKGIAGLNYVIVRPAIVYGTLIIGAVYKSLNEQMKLLWTEKLNTVHVDDVARALFYLTI-YNLADKGDTSQDTVSTILDQIFGIKHSYAG-NITEDVNESHMDPWSKLLKADT-PLSPYLDQLLYNNNTTVDGSKIEKL-GFSLTKDALKNVVDEYVKLG Catan2 IGRNFVAHLIRVVDKTAWLNETHKAAIDIEFRQANLVASIEKAFWDVVVNLAAETKYSQSESVYEEKIVMLSTNCAKEAA--KNKSKFIEVSTAQVYDKKNLDEKAEEELKKIAGLNLVIVRPA-----LICGHIYRHLKEEMKLLWTKDLNTVHVNDVCAALWALSV-YNLADKEDTDQETINAHIRNIFGIQTGFQG-SVTEEVNDTHMAPWSELLKASS-PLTPYLDQLLYNNHLSIVGTKIESVPGFSVTEERLREVVDGYKKQG Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 TGRHLCKYILRIVDKLAWLAPEFKEACSERFIQADAARSLPRIFFDYVFNCGGETRFSQEEKVYELRSYGLSMNIGREAA--KRKVKFVELSTGMVYENIPHKEKAEEDLAKIEGLNLMIMRVAHVYGPLCMARVYQSMGKEMRFLWKEDMNLVHIEDATRALWHGAI-FNIVDHGNTSQKHTAEFMAEIFNIKTGFHG-HVVDEVNEETLDPWAELQSKAT-PLTPYMEKLLKDADLCMDGSLFEKETGFKCTREKIEEVIESYKRMG Coere1 YGRAVIEQLIRGVDKLAYFPTATLKLYEFDYRIGNLRDFIKRAFWDYVINLAAEHKFGQTIGVYEEDVHQVSVNIAKLAV--ENKAGLVQLSTAHLYDNKRHNERAEKDIENIFDEGLAILRPALCYGPLIAAQLSRESGEPMPVLWDKDLNTVHVSDVARAIILVAI-LNLSDPGDTTNAKLAKTVAKLFAVKPSFHN-ELTEEVNESLLGPWMELLANNS-PLSPYLDQRLEYNPLGVDGSKIEKVLGFKISQDALRQMIEEFQQLG Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 CSRALVALLLRIVDKTTYIGAEFAKILNVEYRQANLTAAVAQAFYSLVFDLTGEINYDRGEPIFIQTTFTVARHIALEAT--KRNVAYVRLQLP-VYEKGDHSEETTRMLAGMPELNLVILRIGFVYGPITVASVYGYMSKPMKTLWGPGKNTIHVDDVAGGLWACAV-FNLVDESETTLVSAGNTITSFFGTTFEFYN-DVVDEINEHHVGTWTQMQQMSS-PLNGYMDRALSRHRLAYDASKIKAVVGYKFCRENIREMIDKWKEDG Copci CRLA-----SGIVDKTTYIGPEFPKILEVEYRQANLTATISSVFFDYVFDFTGEVRYDRTEVIQYNTTYCVARMLGLEAA--KRKIKYVRIQQS-FYSKGPQDEETLRGLGAIEDLNLVILRLGFIYGPINVAAVYGYLKRPMRSLWSPGKNTIHVDDVAGAAWAAAL-FNVVDDSNNTLLSVGQTVTSFFGTTFEFLS-DAVDDINEEHVGGWTKMLTENT-PLTAYMDKALEKHTLGFTNGKLKDTLGYSFSHDAIKEIVDKWKAEG Croqu1 HARALLPYLVRLVDKTTYVDKESQRVLKVEYMQANLLNSRTKAFYDYVFDFTGETDYNADEGVHIERTARLLPELAKLGQ--SLGVKYVRELPP-LYNKKPIKEEGVRAMAALPDLNLVIARPALLYGPLLIGEIYKYIDERMEHLWSADLHTIHSHDLANGLWSLAM-FNLVDDGDTTQGVMASMAEKVVGVKTGFYG-DVIDDVNEKHFAPWPEMLSRST-PFTPTLPVLLSKHHIALDGTKVRQVIGWKMTVEAIQDQIQKFKDEG CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 IGRFLALHIVRVVDKLAWLAPEFDEACADKFVQADASQALGRIFFDYVFNCGGETRYSQEDEVYKLRSLGLSLAVGKEAA--KRGVKFIELSTGMIYDSAASKEQAEDQLAKVEGLNLAIIRLAHVYGPLCMARVYKAQDDEMKWLWTKDLNTVHIDDVVRATWAVAI-FNVVDKGVTTQGTMANVIGEIFGIKTGFQG-SVVEDVNDELLGPWAELLESAG-PLTPYMEKLLKDTDLSMDGTRLEKVVGFQINKELLEEVIESYKRMK Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi IGRNLVQYLIRVADKTAFLGAKHLEAFAVEYMQGNLAASITKCFFNIVFNLAGETKYGQTDAVYNEKVYDVSVKCATEAA--KVGVDFIEVSTAQIYNKKPSKEKAEKALKEINGLNLIIVRPSVVYGPIITGAVYKHTNEKMKFLWDGDLNTVHVNDVCKALWFLSV-YNLSDKGDTDAQTISKILEKIFAIKTGFVG-DVCEEVNDKHLKPWSDLCKDKT-PLTPYIDQLLSNTHLSVDGTAIEGL-GFKITEALVREQIDYFINQN Dmel IGRNLATYLIRLADKMAWLNEEQTRVFEVEFCSANLIASCKAAFWDIVINCAAETRANQDDAVYKEGILKLSLNCANEAA--NQRVKYVELSSGCVNEKTPLKEKVEKELANIDDLSYTVVRLPVVYGIIIIAAIYKYLNETMKLLWNDAMNTVHVSDVCAAVWQLAI-YNICDDSASTQGTISNLLVDIFDINLDFFG-DTVSEINDKHMAPWAEICQRNT-PLTPYLDEQLQHKHLYLDNTKLKDF-GYVVTRELLMEMINDYVKQQ Enthi VGRNLVKMLIRSVDKTAYLSKEHASVYDCVFVQGNLVSSVSKMFFDVVFDCAAETKLGQEEFMYEQKTYGLTKLVAEEAV--KQKVKFVHLSNAQVYSSKPKDEKADELLIGMKELPFVILRPAIIYGPIICAAVYKYTKKKMEFLWTGDMNTVHVHDVCKAMMLCGI-YNLCDKNDTNQKKINTILEEIFQIKTGFKG-GVCETVNDEHMKPWSQLCKEET-PLSPYLDQLLYNNPYCIDGSSIEKK-GFVVTTELVKEEIKYFSDQK Falba IGRNFVTHLIRVVDKTSFMNARHKAAFEVEFKQANLSASITASFFDYVINLAGETKYSQSEAIYEERVFNLTVNCAKEAA--ARKVKFIDVSTAQVYGKSPSDEKAEQAIKQIPGLNYVILRPAIVYGPLVVGAVYKQLGDEMKLLWTKDLNTVHVDDVCRAILLVCI-YNLADTGATDQEKITSLVCKIFGIKSSYHG-SATEEGNEKHLQPWSELCKAET-PLSPYLDKLLSNNALSIDGSLICKELGFSVTEELLRDVLRLAIETR Fomme1 WSRRFACHLLRIVDKTTYLGSDFKDVLPVEYKQANLTATVSRMFYSYVFDLTGEVRHDRLDMIQISQTVNIARLVGEEAA--RRNVKYVRVTHP-FYEKGIHDEETLRVLANIENLNLVILRPGLVYGPMAVASVYGYIKKPMKGLWSPGKNTVHVDDVAGAAVALAL-FNLVDESNSTLVSIGSEICSVFGTTFGFHDTSVIEDINEEHVGGWTEMLQSST-PVTAYMDDILQKISVAFNAEKIKNVVGYQFSQEELKDIVDRWKEEG Fusgr1 IGRFLALHIVRLVDKLAWLAPEFSEACSDKFMQADASEGLARIFWDYVFNCGGETRYSQEDEVYKLRSLNLSIAVGKEAA--KRGVKFFELSTGMVYDSSPSKEQAEEELSKIEGLNLIIVRLPHVYGPLCMARTYQHLEDEMKWLWTKDLNTAHIDDVTRALWDIAI-FNIVDEGATSQGTIATIIGDIFKIETGFQG-SVVDDVNDELLGPWADLLADAG-PLTPFMEKLLKDTDLSMDGTRLKTLLGFELTKELIEEVIESYKKMK Galma1 CSRALAAFLLRIVDKTTYIGPEFTKVLETEYRQANLTATIESAFFDYVFDFTGEVRNDRSELIQINTTFAIARLLGLEAA--KRKVKYIRIQQP-FYAKHAALEESIRMLASIEELNLVILRIGFVYGPMTVASVYGYMNKPMKSMWSPGRNSIHVEDVASGAWCCAL-FNLVDDSKSTLLSTGKTISSFFGTTFEFFN-DDLEDINEHHVEGWTEMLQNST-PVSAYMDKTLEKHVVGFDNSKIKQIVGYKFNHANIKEIIDKWKEEG Ganpr1 IGRNLVSYLIRVVDKLAFLHPSHKKAFDCEFRQGDVSAVAEKMFFDYVFNLAAETKYGLSEEIYEEKVYTLAITVGKEAA--KRGVKFVQASTAQVYDKKPAKEKAEEELKKIPRLNLVIVRPAVVYGPLIMGAIYRQLAQEMKLLWTASLNTVHVSDVVRALWWVAV-YNLADGGDSNQETINTHIRSIFGITTGYQG-SVTEDVNDMHLQPWADLCKAGT-PLSPYLDRLLKDNELYVDGGKIEST-GFKVTEASLREVIDGFVEVG Gloin1 IGRNFVPYLIRVVDKTANLNPRQREAFEVEVKQKDLVASIKEVFYDYVFNLAAETKYSQNERVYEERVYLLSVRNAEEAA--RRRVKFVELSTAEIYDKNPSKEKAEEKLKTIEGLNLVILRPAVIYGTIVCGRIYQYTKEEMKFLWAKDLNTVHITDAVRAMWHTAI-YNLADQGNTDQEKINKHISNIFNIQTGFHG-NATDEINDKHMRPWVTLLRTNT-PLSPYLDKLLYNNALSVDGTKITKETGFEITDEKIQEMIDDFIVLN Hisca1 LGRFLALHIVRIVDKLAWLTPEFSAACSDKFVQADASQSFSRIFFDYVINCGGESRLSQPDDVYRLRSHVLSVALGKEAA--RRGIGFIECSTATVYDREPAKEQAEEDLRKIPGLNLCILRFPHVYGEICMGRAYMELGKPIPFLKTGSQNTVYVKDAARAMWRAAV-FNIVDHNKTTKNDLAQGLKKAFGIEYNFVG-EIIDDMNEEGLQVWAELLNEKG-PISPFLERSIKDGDLLIDGSLFEQTTGFMLGEDWIQPVVESFKRLG Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 CSRALAALLLRIVDKTTYIGVEFPKILEVEYRQANLTSTIQSIFFDYVFDFTGEVRHDRTEMIQINNTCKIAHMLGREAA--KRKVKYIRMQHP-FYAKGTHDEETLRVLASIEDLNLVILRIGFIYGPINVAAVYGFMKKPMKSLWSPGKNTVHVDDIAGAAWASAL-FNLVDDSESTLLSIGQTVTSFFGTTFEFFT-DDVDDINEQHVGAWTDMLMNST-PLAAYMDKALEKHVVAFNNAKIKAIMGYKFNHDTIKEVVDKWKAEG Lenti61 CSRTLAALLLRIVDKTTYLGSVFPDVLKVEYRQANLTATVASCFFDYVFDFTGEIQWDRPEGIQIGHTFKIARLVGLEAA--KRKVKYVRIQHP-FYESGSHDEEALRALGAIEDLNLVIVRTALPYGPIAVAACYGHLKQPMKALNSPGKHTVHVDDIAGAMWAAAL-FNIEDDSKLTFVELGNVVASFFGTTFDFHN-DIIEDINEVHVSTWTTMITTST-RFSSYMDVNLKKHVVAFNADKIKNIIGYKFNHEALRDMVDKLKAEN Malgl1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 HARALLPFLVRLVDKTTYVDKESQRVLKVEYMQANLLTSRTKAFYDFVFDFTGETDYNVEEGVHIERTARLLPELGRIAA--ECQVKYVRELPP-LYNKKPIKEEGVRAMAALPTLNLVIARPALLYGPLLIGEIYKYIGERMEHLWSADLHTLHSHDLASGLWALAM-FNLVDDGDTTQGMMATMAGNVVGVKTGFYG-DVIEDVNEKHFAPWPEMLSKST-PFTPTLPVLLSKHHIALDGTKVKKVVGWTMTEEVIKDQIEKFKEEG Mnele ---------------MAWLSEKHKAAFEVTFKSINLLSNIDKI-FDYCVNLAAETKLGLSKEIYEERVTKLAQNCATFAK--EQDVKYIELSSAQVYSGKTSKERAEEEVAKVPGLNHVIVRAGMVYGPLVIASIYSHLGETMRLIWNKNMNTVHVEDLCHAITHLVT-YNIVDKGDTTLDGICRHVAHIFDIKYEYIS-DVAEDVNEKHLAPWSEMCSKDT-PLSPFIYSQLETLNIRACNQKLLNT-GFQITEANIRDVLEDCIKIG Monbr IGRNLVVYLIRVVDKTAYLTARQQAAFEVDFQQGNLTATIQKAFFDFVFNCAGLTTYGQAPEVYQESVFDLSVKCARAAA--QSGCRFIELSTAQVYDKKASAEAVENELKAIDGLDYCIVRPANVYGVLITAAVYKKLGETMKFLWSDKLNTVHVSDVAAALWTIAV-YNLADKANSTQGSVADLLAQLFGIEVGFVG-AVVETSNEKHMEPWSRMCVDAT-PLTPYLDKLLYNNSLAVDGSKIEAL-GFEPTLDLLRDAVEAEIELK Morel2 IGRKFVAYLIRVVDKTAYLNKRCTAAFDVEFMQGNLSASIEKAFFDYVINFAAETKFSQPNEIYEERIYRLSINCAKEAV--KRNTKFVQFSTGDIYDGTASKEKVDNELQEMAGLNLIILRPAVVYGILICGRVYQHLNQKMEFLWTKDLNTVHVLDVAKAVWHTAV-FNLADENDTDQEAVNAHIRAIFGIETGFQG-GATEDINEMHLAPWSDILKAHS-PLTPYLDQLLYNNAVSLDGTKICTTTGFVLTEASLREIIVDFQDLG Mucci2 IGRNFVHYLIRVADKTAYLSETFKTEFSIEFKQTNLIASIAACFFDYVFNFAAETKYSQVPEIYQERIFNLSVNCAKEAA--KRNVKFIEMSTAEVYNQEASTEKAEEALKKIEGLNLIILRPAVVYGPLIIGRIYKYLDEEMKLLWSKDLNTVHVDDVSRACWFLAV-FNLVDKQDTDQEAINKQLQAIFDIKTGYHG-AVIEAVNEKHLAPWAELVKKDT-PLSPYLDELLYNNALSVDGSKIERETGFTLTREKLIEIIDGYKALE Mydma IGRHLVTYLIRVADKLSWFNAEHKAVFEVEFFQANLVAHVERVFFDYVINLASETRYGQGDEVYTEHIYNLGVNVATKSA--SCKVKYIELSTAQVYDKKASDEKLEKKLREIEGLDYVIIRPALVYGILIIGAVYKQLQEKMKLLWSKDLNTVHVNDVAIAIWFLCV-YNLVDKQDSTQGSISELVCQIFGIKYDFFG-GVVDESNEKHLAPWSVACTADT-PLSPYLDKILYNNHLHIEGTKIESL-GFKVTAEDLKLVVQDYVTLG Neucr2 IGRFLALHIVRIVDKLAWLAPEFEEACAPKFMQADASQSLQRIFWDYVFNCGGETRYSQEEEVYKLRSLELSLAVGREAA--KRGVKFIELSTGMVYDSAPSKEQAEEELAKIPGLNLAIVRLSHVYGPLCMARVYQALGSEMKWLWTKNLNTVHIHDVTRALWQVAT-FNVVDKGRTTQGIMADLIGDVFGIKTGFQG-DVVEDVNDELLGPWAGLLEDAG-PLTPFMEALLKDTDLSMDGSRLEELLGFKINKELLQEVIESYKRMK Orpsp11 IGRNLCSYLVTVADKTAYLSAKHKAAFDLTFKQANLTAAVEKIFYDYVFNLAAETKYGQSEAVYDEKVFGLSVTCAKEAA--KRNIKFVELSTAQIYDKKPSKEKAEEELMKMQGLNLVILRPAVVYGPLIIGAVYRQLNEEMSFLWTKDLNTVHVSDVVRAIWHVSI-YNLADKEDT------------------------------------------------------------------------------------------- Pench1 IGRHLALYIVRLVDKLAWLAPEFEEACSDKFVQADASQHFPRIFFDYVINCGGESRHSQPDDVYEVRSYALSVALGKEIA--RRGIPFIETSTAHVYGSTPRKEKAAEELLKVPNLQYCALRLPHVYGAICLSAVHVDLKQDLEFLHTKDLNTLHVKDAASALFEAAT-FNVVDHNDTKQEHVANALTEVFGLKVSFIG-DVLDDMNEVGLQTWAELVERAG-PISPFLERIVRDQDMSIDGSKFENETGWKFGADSIREIVDSYKRMG Phybl2 IGRHFVHHLIRVVDKTTYLSESHKASFEVEFKQSNLIAAIATCFFDYVFNFAGETKYSQVAEVYQERIFHLSVNCAKEAA--KRKVKFVELSTAEIYDNSASSEKAEEELKKIPGLNLVILRPVVVYGPLIIGRIYQHLNEEMKLLWSKDVNTVHVDDVARACWHVAI-FNLADKEDTDQETINRHLRSLFGIQTGYYG-YVMEDVNEKHLAPWADLLKSST-PLSPYLDELLYNNALSVDGTKIERETNFSLTQAKLREIIDGYKALK Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 SSRTLAALLLRIVDKTTYLGAEFPKVVAVEYKQANLTAPVASAFYDYVFDLTGEVRHDRPEQVQVNHTFNVARLIGLEAA--KRKVKYVRLQQP-WYEKGSHNEETLRMLAAIPDLNLVILRIGFVYGPITVASVYGFLKQPMKSLWAPGKYSVHAADVAGGLWACAL-FNLTDDSDSTMAKTGSVVTSLFGTTFEFMG-DVVEEINEAHVGAWTQMITTST-PLSAYMDTTLSKHMVALSNTKIKEVIGYKLSHDALKEMVDKWKAEG Polpo IGRNLVQFLIRVVDKTAFLNAAHQAAFGVEYMQGNLTASIAKVFFNYVFNLAGETKYGQTEAVYNEKVFEVSDKCATEAA--KVGVDFVEVSTAQVYKKKASKENAEKKLREIPNLNLVIVRPSVVYGPIITGAVYKHLAEKMQFLWTGDLNTVHVRDVCKALWHVAL-FNLSDKGDTDAEMISKILEKIFQIKTGFLG-GVCEEANNKHLKPWSDLCKDKT-PLTPYIDQLLYNNHLSVDGTAIEAT-GFKITDALVREQIEYFTSQR Pucgr2 HARALLAFLIRLVDKTTYMDSECQKILKVEYLQANLLSSRSKAFYDYVFDFTGETDYNAEEGVHVERTGRLLPELGRVAA--AMGVKYIRELPA-LYNKKPLKEEGVRAMAALPDLNIVVARPALLYGPLLIGEIYKYIGERMEHLWSSDLHTIHTHDFAAGLWALAF-FNLVDDGDTTQGLMASLAEKVVGVKVGFYN-DVIEDVNEKHCEPWPEMLSKST-PFTPNLPRLLTKNHIAFDGTKVKEVVGFKMTEEAIRDQIQKFIQDG Punst1 CSRALAALLLRIVDKTTYIGSEFPKILEVEYRQANLTAAVATAFYEYVFDLTGETRHDRPEGVQLMHTFNISRLVGLEAA--KRKVKYVRLQHP-FYEKGSHEEETLRMLAAIEGLNLVVLRIGYVYGPITVAAVYGYMKKPMKALHPPGKNTVHVDDVAGGLWAAAL-FNLVDDNETTLLKAGQTATAFFGTTFDFYN-DVVEEINEHHVGGWTEMIQKST-PLTGYMSTDLQKHVVAYSNAKFKKVVGYTMGPPELSDMIDKWKADH Rhior3 IGRHFVHYLIRVADKTAYLSEKFKQDFEVDFKQCNLIASIASCFFDYVFNFAAETKYSQVKEVYQDRIFNLSVNCAKEAA--KHKVKFIEMSTAEVYNTKPSKEQAEEELKSIEGLNLLILRPAIVYGPLIIGRVYKYLNEEMKFLYSKDLNTVHVKDVSRACWYLAI-FNLADKQDTDQEVINRHLQSIFKIDTGYHS-AVVEAVNEKHLGPWAEIIQQNT-PLSPYLDKLLYNHSLCIDGSKIENETGFIVTDENLNEIIEEYKTLG Rhoto1 NARHLLPYLIRVVDKTAYVDTACREAFKVEYVQGTLLAMRTKAFFDWVFDFTGEISFEAPEAVHVERTLQLALLLGAAAV--KHKVGYVRGIPC-FYDDRTGKVEAARGLAKLEGLNLVLVRRAVMYGPVLIGEVYKFEGDKLEFLWADSLSTIHAADYAAALVKSAV-FCAVDDCETTQKEIASIIQEVVGVKSGFHG-DVVEDANDKHLEGWSALLQASTIPISPSVPAVLAPHPIAFSNAALKKHTGWALNKEIVRETVEGFKREG Rozal11 VGRNLVHYLIYVIDKMSFLSKEHQNSFSIKFKQLNLCNACQEFFIDVIVNLAAETKYGQSES----KGYWASLEIS---------VKFIEVSTGQVYDKKPSKEQVENLLEQTENLPWIILRPAIIYGPLTCGAVYKELKQKMEFLWTKDLNTVHVNDVARAIFHVII-YNLVDHANTDQENVNSCIRDIFKIETGFHG-SVVDEANDKHMKPWSTILTRAS-PITPYLDKLLSNNSLCLDGTKIEQT-GFELSRELILESLQYFVDQN Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro IGRHLVVYLIRVADKTSYLTPRQQAAFDVEFVQANLAAFVAKAFFDYVFNCAAMTKFGQDELVYQENVVDLSCKCARKAA--ELGCKFVELSTAQVYDKKPSDEKVEQELASIPNLDYVVARPAIVYGSLIVGAVYKHIGETMKLLWTEKLNTVHVEDVAAALWTIAV-YNIADKADTTQGSLNEQLSQLFGIKTGFFG-AAVEESNEKHMQPWSDMCRDAT-PLSPYLDKLLYNNSLAVDGSKVESL-GFEPTLEELRRIVEEAVEQK Schco3 YSRALAAHLVRIVDKTTYIGAEFPKILDVDYHQANVTSTIASMFYDYVFDFTGEIRPDRLEKIHIQWTFNVARLIATEAA--KRNVKYVRLQLP-FYSKTPATEETLRMLGAMENLNVVALRIGHAYGPITVASVYGYLKKPMKSLWGPGKNTVHTDDVAGAMWACAL-FNLVDDSNSTFASAGSTVTELFGTTFEFFN-DVVEDINEHHVGGWTEMVQKST-PLSAYMDAQLEKHVCAFSNQKIKDVVGYKFDHEGIREVVDKWKEEG Schpo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma IGRFLALYIVRIVDKLAWLAPEFEEACASKFMQADASQSLQRIFWDYVFNCGGETRYSQEDEVYKLRSLELSLAVGKEAA--KRGVKFIELSTGMVYDSSPSKEQAEEELAKIPGLNLVIVRLAHVYGPLCMARVYQALGSEMKWLWTKNLNTVHIDDVTRSLWQVAT-FNVVDKGHTTQGTMADLIGDVFSIKTGFQG-DVVEDVNDELLGPWAGLLEDAG-PLTPFMEALLKDTDLSMDGSRLEELVGFKINKELLQEVIDSYKRMK Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 IGRNFIAYIVRVADKTAYLSDKHKKVFDVEFKQANLTAAVEKIFFDYVFNLAAETKYGQSDEVYDERTFQLSVAVAKEAA--KRKVKFVEVSTAQVYDKKPSAEKAEEELKKISGLNLVILRPAIVYGWLIMGAVYRQLNEKMELLWTKDLNTVHVDDVARALWHVAI-YNLADKTDTDQGKVNQHIQAIFGIDTGFQG-SVTEDVNDKHLQPWSELCKAAT-PLTPYLDKLLKDNALSVDGSKIEKELGFTLTEQELRKVVEEFVASN Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 CARALAAYLLRIVDKTTYIGSEFPKVLEVEYHQANLTATVSRMFYTYVFDLTGDIVVDRPEAIYINHTCNVTRLLGLEAA--KRNIKFVRLQQP-FYEKGSHEEESLRILGAVGGLNLVVVRPGLVYGPLTVASVYGYMKKPMKSLWSPGKNTIHSDDVAGALWACAL-FNIVDDNQTTLHKAGETMTSLFGTTFEYHN-EAVEDINEAHVGAWAEMITKST-HLSAYMDTTLSKHVVALSNAKIRKIIGYTMTAENLREIVDKWKEEG Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr IGRNFVHHLIRVADKTAYMDEAHAASFAVEFRQANLTASIEKAFFRFVINLAGETKYSQPETVYAEKIAQLTTKVATAAA--KHGVEFVEVSTAQVYNKKTKSEQAEEALAGIDGLNYVVVRPAIVYGPIICGAVYKQLGEKMEFLWTKDLNTVHVDDVVRALWHLTV-FNLADKGNTNQGKVNEILEAIFGIDTKFAG-GVTETVNEKHLKPWSDLCKAAT-PLTPYLDQLLYNNHLCIDGSKIEGT-GFTINEELVRAQIAYHVSQG Treme1 VSRPLIHYLIRLVDRTTYLDKPFLTLLDIEYKQINLSSRHTELFFDVVFDLTGEPAFDKSELIQISNTYQIALSLATSASQLDPKLRYVRLTFP-FYSSAGHAEETVRGIGRLSNLNFGVIRSGAMYGRLVIGHVYKSLNEEMKFLHNPDLNTINTIDISQALYLLAL-FNVVDDDDATQEKLAKVVAQVWGIKYGFLG-EMVEDVNELHVEAWAKMLAATT-PITPFLDEAFRKLAICLDSSKARRILGFKIEVEELKVIVKDFQDDG Trire2 IGRFLAQHIVRIVDKLAWLAPEFSEACASKFMQADASEALVKVFWDYVFNCGGETRYSQEDEVYKLRSLDLSLAVGQEAA--KRKVKFVELSTGMVYDSSPSKEQAEEALAKIEGLNLVIVRLPHVYGPLCMARVYQHIEGEMKWLWSKDLNTAHIHDVSRALWDIAI-FNVVDKGATTQGTMADIIGEIFKIETGFQG-SVVDDVNDEILGPWADLLSDAG-PLTPFMEKLLKDTDLSMDGSRLESVVGFKITKELVEEVIESYKQMK Umbra1 VGRNFVQYLIRGIDKTAYLSPAVKAAFDVEIMQANLIVSIEKCYFDYVFNFAAETKYSQVSEVYRERIYNLSVNCAKEAA--KRHIKFLEMSTSEVYNKEPSTEEVCKTLKNMEGLNLVIVRPAVVYGVLVIGRVYKKLDEEMKLLWNKDLNTVHIRDVVRACWHLAL-FNLADKQDTDQETINQHLETIFGIKTGYHS-TVTEDVNEKHLGPWADLLKESS-PLSPYVDELLHSHPVSVNGTLIERETGFTITKEKLEEIINGYKELK Ustma22 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 LTGSLLNELIKIIDKTTFIDDHFKELL-VDYQQANLLGLIDDLF--TVYDMTGDIRFDINELQHIQSTL-ISYQLGTIAS--NHNLRYVKLTYP-FYS-----EESIRSLSSISNLPLVVLRIGAWYGPIICADIYRHLKEDIKFLWNADLNTIHSQDVARALIALSL-FNLVDESDATQSSVADQIAKVFKVKTSFLG-EMVQDVNEMHLDAWSDMLKKST-PLTPYLDEFFKKNPIALDASKISKTIGFKITVEDIEGIVKGFRDQG Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3085.fasta_al_trimmed; alignment length = 193] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ANLNAFKSKIKTAAHQD-SGSHSSAAKKMKSPQKAA-VSTKMLIATEYIQEPIDQIPMLKGLAKFKFDPKKNTLQYVDVHSAEELLKLTRTQGISCKELKDG-WP--Q--CFEVIDELEKKNRILVSRTKDNS-PRVWYNFGGKMWENCKLPELPRKLQDLGLKPASEAKKR-KQRK-ITNTHMAG--I--LK Aspfu1 QQLKSFNASVTDYSTSTSQVPSSDAQRKRQVYSQPANTMTQVLFAVEHLKSRYSDIRILTQHEKVLYDPSEGTFAFRNIRTAEQLLQKLQSQGMSVRELREG-WP--N--VEETINRLEKEGKLLVTRNKDDH-AKVWANDPSQIWAKIKVPAVKEELEKAGITPTSQKKVK-KPRK-TTNTHMMG--V--LR Aurde31 -------------GSGLEP----EQKKKRPVFSQPADTNTQLVYAVKHLKDRLQDLERFKGHDRVLHDEKTGLFSYRNLKNKATLLTEIQRHGLSVRQLKES-WK--E--APAAIDELEKEGEVLVTRTKDGQ-MKVFWNEVRSMWHSLVVPDMLRVLRAEGLQATQ--KKK-GKKR-IMNTHLQQEGIDLSK Batde5 SSKAELRRRMLAQATEVDPNK--NIQTKVVLYSSD---ARKLFDIIMLLKATNNDMDLVRNNERIFYDGVNGTFEYRKIRSKEDLLELLKKNGMEVKELKDS-CN--G--IFGYIEELDAEKSILIIRNRDES-PRVYYNNNQEYWHQVALPDISKELASAGLKSMEAKTKA-KRKK-LTNTHLEG--IDLTK Botbo1 RDRSSFLKKMGNAAQPAAPATTLGKKKKRPVYSQPAEKNTQIFYALEYLKKRIEDLSKFKNHNQVIYNPKTDTYAYKNINNLEALIREIKFHGLTIRTLKES-WP--S--APAAIEDLEKAGKVLVTRTKDGQ-AKVFWNEMPDLWHSLTVPDLLRSLASDGLQATM--QKK-SKKK-ITNTHLVKLGIDLTK Botci1 KQQAAFAKGIQNTPSNTSNTSKS-KRKREPVYSQPASTFTQVTYVIEFLKKTFQEIQILRRHDRVQWIADSGTFKHRGVRNKGALLSYLQNKGVSVKDLKDG-WP--D--CEDAINELEKEYKILVTRTKDNH-ARIWINDPTVMWHRTELPDLVRKLLENGQKPASEKKRK-APRR-TTNTHMAH--L--LN Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 AQLSAFKNKIKSGSSSTTTTTSKRVLKKQK-------ASTQLHLAVEYIKESVEKLPLLNEIDRVKYDESKGTLEYVNIRSSDDLLEFLRRQGTSVKELKDG-WA--G--CVAAIDELESQGKILVLRNKENA-PRVWANNGGDMWDQVKLPVLYQKLLDQGLKPTGEKKQK-KARK-ITNTHMKG--I--LK Cangl ANLKAFKSKVKSANSNTSVNNSDSPSKRVKAAAALQ-ASSKLLWATEYIQKPLTELGLLKKLERIEFDEKKSTFKYLDVHSAQELLTLLKNQGISFKDLKDG-WP--Q--CEETINDLEEESQILVLRTKDKT-PRVWYNRGGKVWENVQLPELPRKLQELGLKPASEVKKK-RNRK-ITNTHMAG--I--LK Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ANSSS--------ANAPSPTPSTGSKRKRPVYSQPQDTFTRLTYVNDFLRESFEDIRADNQGNRISWDSQNERYKYKDIHNRAQLKGHFQTQGLQIKDLKDG-WS--N--VAEDITKMEEKNEVLVRRAKDGV-PKVWANDPSKTWHSVQVPEELRKVLLANKMTAATKKKK-GPRK-QTNTHMIG--I--LK Coere1 AQQKEFRKRVATQRRIVNPST--AMSSRRPTEEEPEAALTRVYQVIDFLVKTANEIQHLANNAKVIYNSEDNTFAYKDIRTPEDLVEYLKQLGLEVKKLNDS-YLADK--LSKVIADLRERK--LILATKDNR-PRIFYNHWPSSWIRLVVPELAIEMKKADLKPTQVKKPK-KNQK-ITNTHLVG--IDLTK Conco1 --------------------------------------NSSVFAVLNYLKKSLENIERLRANPRIKFLPNSHMFEFLDIRTAENLLAAVEDRCFEFKELLDS-NS--N--VKPLIEQLEEDGKIFVTRKNDNN-IKIYFNPHKSVWSSLKIPDLTRDLKSAGMKTSEPKKKS-SSNK-LTNQHLEG--IDLT- Conpu1 --------------------------------------NTQLVYAINHLKSRLQDVEKFKAHDRVQYDPKTDLYSYRSFRNKAALLTEIQRQGIPVRALKES-WK--E--APQAIEELEKEGEVLVTRTKDGQ-LRVFWNEIKDLWHQLKVPDLLKALKSEGLQATA--KKK-GKRR-ITNTHLKG-SIDLSR Copci QDAAAFKSVMHRQTQAASTSTATPAKKKRPVFSQPADTNTQLVYAVSYLKNRLDDLEKFKAHDRVVYDPKTDLYSYKTFRNKASLLTEIQRQGLSVRALKDS-WK--E--APAAIEELEQEGDVLVTRTKDGQ-LRVFWNEIKDLWHELKVPDLQKELASEGLQVTA--KKK-GKRK-ITNTHLRG-EIDLSK Croqu1 RFAPQKPSPLSQAPAKPPPTNSSSKPKKKS--APPTSTATQIFTLVDALKANLSDLDAFNKHDRVNVTERVKLWSYRLISNPQQLLELLQRFGMPIVTLKQS-WP--N--VMSAITELENEGKVLVFRTKEGV-VKVFYDELGEMWHSLETPTLPQELQEAGLTSSTKSKKK-GRGK-ITNTHLKDLGIDLSK CryneH991 PQSPSVKHEIKDE----------PDAKRVK---KPILTRTAAYALLNQLKKGWEDAEIFKTLERVEFNKINRVFTYITLTTTNEIRNHIRIHGIPIKTLREA-MP--N--GIEPLKDLEARGDILIMRGKDIPLPRVFWDHLRYSWADVPIADVAKLLADQELS---ASKKK-KKRK-ITNTHMKEQGIDFSK Crypa2 RQR------VASAPPSPSPSVAS-TKKRRPIYSQPALTGTQMVYAVNHLKETINDIENMRRHPRVRWTPDSGTYRHNGVRSKETLLAYLQAKLVHVKDLEDG-WPRER--LYPAITELEREHRILVVRTKDNH-PRVWQDDASVMWHKVNVPDINRLLLAAGQKPASKPKKK-AKKRNVTNTHLKG--H--LS Debha1 AQLSAFKNKIRSGKSNDSSNANPEAIKRQK-------ASTQLHLAVEYIKQTVSKLPLLKEIDRIKFNPEDNTLEYVNIRSSDDLLNFLRSQGISVKELKDG-WA--G--CLQAINELEEQSKVLVLRNKENT-PRVWANLGGDMWSNVKLPSLYQALIDQGLKPTGEKKQK-KARK-VTNTHMKG--I--LK Dekbr2 SQLTAFKRSLKRA-PSDSRNESKQRRKRQKSDSFTDLSSIRLMNASDFIKGSIKELKCLSNVDRIKYDPMNKTLEYLNIKTAEDLMKVLENQGLSVKQLRDG-WN--G--CLPTIAKLEKENKIIVHKTKENA-PRIWLNFENDMWEKVAVPDLVKTLLSNGMKPTNRRKQK-KPRK-ITNIHMRG--I--LK Dicdi ---AGFKETQMKANSIKKPSSSTSSSANRQLRDK----NRIVYDIVNYLKTDTKEIELLRNNEKIID---NDRFSFKNVRTQRDILDLLPNYGILVSELAES-YN--N--AESDVKKLKETKQIFAIKAESAC---IFPNDERDMWKSIKLPDLEKEMKDAGLSVVEKL-KKERKKK-VTNTHIEN--FNPND Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 RDAAAFKSSLQRQNNAPPPSSGTTAKKKRPVYSQPADTNTQIVYAVDHLKNRLQDLERFKAHDRVVYDPKTDLYSYRTFRNKAALITEVQRHGLSVRALKES-WK--D--APQAIEELEKEGEVLVTRTKDQQ-MRVFWNELKDLWHKLKVPDLLKALSSEGLKATE--KKK-GKKR-ITNVHLKG-DIDLSK Fusgr1 KQANAFRGTLSSAPSSPSPSAASTKRKRDAPYSQPQLTKTQMTFAVEYLKKTITEIEGLRGHPRVDWKPDTGTYAHRGVKNATTLLGHLQAKGVSVKDLKDG-WP--D--CEDTISALEREYKILVVRTKDNL-PRVWPNDASSMWQRVQLPEMHRKLTSVGQKPTSVQKRR-KGNK-ATNVHMAH--L--MQ Galma1 KDAASFKSTLQRQTSSTTPSTPGSGKKKRPVYSQPADTNTQLVYAVNHLKSRLQDLEKFKAHDRIQYDPKTDLYSYKTFRNKAALLTEIQRQGISVRALKES-WK--E--APQAIEELEKEGEVLVTRTKDGQ-LRVFWNEIKDLWHSLKVPDLLRQLASEGLQVTA--KKK-GKRR-ITNTHLKG-EIDLQR Ganpr1 DDLAKFKATQQRAAAASTPNQRTPNPKKRPSLIQPAALSQALLAIIDFLKGPYEHISLITSNNHIIRDEAAKTLSYRNIKNKTDLLNVLRQHAIDIKELKES-YP--K--ALEAVEALATDKKCIVIRKKDDS-IRVAYNEDDTLWHETKIPDLAKELDKVGLKALQDQKVK-KKRK-ITNTHLKD-EL---- Gloin1 ESILALKKQQLAASNAPSTTSQSSSKKKKQVYSQPTDT-----------ERTAEDLNHMINNEKIHYNSVDHTFQYKAIRSKEDLLNLLKER--------------------------EKEG---VSRG-----YR----------------------------------------------------LD--- Hisca1 NQINQFSSSVVSAAAGSSSVATSVANGRRHVYSQPANTMTQVVFAIDHMKSKFADIRILQSHDKVEYDPSEGTFRFKNIRSAEQLLRKLQSQGMSVRELREG-WP--N--IVQAIDKLEEEGKLLVTRNKDNQ-PKVWANDPSQIWEKIKIPTVTDELEKAGITSTSHKKVK-KARK-TTNTHMVG--V--LR Klula1 ANLNAFKNKVKTSANKDRDGQTNSDEKDMPAKSSSV-ASTKMLIATEYIQEPVDQIPMLKGLQKFKFDPKRNTLQYVDVHSAEELLQLLRSQGISCKELKDG-WP--Q--CFDTIDELEAKNRILVLRTKDNS-PRVWYNHAGTMWEACKLPELPRKLQDLGLKPASEVKKR-RSRK-VTNTHMAG--I--LR Lacbi2 KDAAAFKSALHRQSSAASPAASAEGKKKRPVYSQPADTNTQLVYLVDYLRGRVEDLEKLKSHDRVQVDPKTGLFSYKNFRNKAALLVEIQRQGISVRALKES-WK--E--APAAVEELEKEGEVLVTRTKDGQ-LRVFWNEIKDLWHELKVPDLSKQLAHEGLQVTA--KKK-GKRR-ITNTHLKG--IDLSK Lenti61 RDAAAFKSALHRQGSSAAPAT--SKKKKRPVYSQPADTNTQLVYLVSHLKARLQDLEKFKAHDRVIHDPKTDLYSYRNVRNKASLLTEIQRQGLSVRTLKES-WK--E--APQAIEELEKEGEVYVTRTKDGQ-MRVFWNEVKDLWHDLKVPDLLKALASEGLQATT--KKK-GKKR-ITNTHLKG-TIDLSR Malgl1 --------------------------------------------------------QRFKQHPKVRYDEKTDLWSYKEVHSAGDIVSLLRKKGMRVAELRES-YP--P--AREAIEELANEKQVLVLRGRDGS-IKVFWNPIQELWHSLNVPDLATDLENEGLSATKQRGKK-GKRK-LQNTHLKG--VDLSR Mellp23 RFAPQKPSPLSQKQQIKSTSSSATKTKKKS--VQPVS-ATQIFKLVDALKTNLSDLDAFNNHDRVNVTERVKLWSYRLISNPQQVLELLQRFGMPIVTLKQS-WP--N--VMSAITELENEGKVLVFRTKEGM-VKVFYDELGDMWHSLETPTLPQELQEAGLSSSNKSKKK-GKGK-ITNTHLKDLGIDLSK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 NATSEFKKRLADQGSNANPNNNGSKKKKTEVYSQPQDTNSLLLNAINFLKTTVDDLNLLKMNDKVAYDTRDHTFAYKHIKNKEDLLALLEKRGMDYKELKDS-YS--K--LLEAVNELASEGRILVVKNKDGA-PRLFWNDQRDIWHRLRIPDLPKELEKAGLTHMQKRKPV-RRNK-ITNTHMKG--LDLTK Mucci2 --------------SVAY------------VYSQPANTMSQLYTVIQFLKDSVVSIEKLVNNNKIEFDAANKTFAYKQIRSKEDLLSLLIQKGMDYKDLKDS-YS--K--LSSAVEELASEGQILVVRNKDGN-PRLFHNDSQKMWAEIPIPDLPKALEVAGLKTMEPKKSK-TRNK-ITNTHLAH--IDLSK Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RQQASFMSSMSAAPPSPSPSVGSADRVDTPVYSQPAATITQVTYAIAWLRGTYLEIEAMRRTREIQWIPDSGTYLHRGVRNKTQLLAYLQKKCVGVKELKDG-WP--D--CEKAINELEAEHKILVIRVKEGS-PRVWLDDPSVMWQKVEVPTIVQRLKAASQKPASEKKKR-AQRK-ATNTHMEH--L--LK Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 NQLKSFNASVVESSGSSSQVPSSDIKKKRHVYSQPANTMTQVLFAIEHMKNKFSDISILQMHEKVEFDPSEGTFRFRNIRNSEQLLKYLQAQGMSVRELREG-WP--N--VEEEINRMEKEGKLLVTRNKDDH-PKVWPNDPSQIWDKIKVPVVKEELDKFGITPTNSKKAK-KPRK-TTNTHMTS--I--LR Phybl2 DQVKKFKNTLTANPSVGYIANNTSQEAR--VYSQPANTMSQLYTVIQFLKDSVVSIDKLVQNSKIEYNPVNKTFAYKQIKSKDDLLSLLTSKGMDYKDLKDS-YS--K--LANAVEELANEGRILVIRNKDGN-PRLFYNDMQKMWADIAIPDLPKALEDAGLKTMEPKRSK-TRNK-ITNTHLSH--IDLSK Picst3 AQLSAFKSKIKSGASNDS-----EVFKRQK-------ASTQLHLAVEYIKQLVSKVPLLKEIDRIKYDPEQNTLEYVNIRSADDLLTFLRRQGIAVKDLKDG-WA--G--CLPAINELEESNKILVLRNKENA-PRVWANFGGEMWNSVKLPNLYQALIDQSLKPTGEKKQK-KARK-ITNTHMKG--M--LI Plicr1 RDAAAFKSALHRQNGGAPPAAPTSSKKKRPVYSQPADTNTQLVYAVNHLKSRLQDIEKFRAHERIQWDQRTDLYSYRNFRNKAALLVEIQRQGIPVRTLKES-WK--E--APAAIEELEKEGEVLVTRTKDGQ-MRVFWNEVKDLWHSLKVPDLLRSLASEGLQATA--KKK-GKRR-ITNTHLKG-EIDLSR Polpo ------KSLHLRAEKHKKQDEAK-SSHKRPLASKPMYLTRMVYDIVNHLKSTFEELDQLKTNIKVEF---DTTLCYKNVKDDRGILELLSKHGIMLSDLKES-YL--A--VEQDVKKLKDSKEIYAVRNESNS---LFYSDEKDLWKSVVMPDLEQTMKDAGLSMVEKVEKKDKKRK-VTNSHIAD--FDPNA Pucgr2 RFAPPKPSPLSQPPQ---PSANAAPPKKKK--AQPTA-ATQVFKLVDTLKRNLSDLDAFNSHERVNVTEKVRLWSYKVINNPKQVLELLERFGMPVNTLKQS-WP--N--VMTAITELENEGKVLVLRTKEGT-PKVFYDQLGEMWHSLQTPSLPSELQEAGLTSSTKPKKKGGKGK-ITNTHLKDLGIDLSK Punst1 KDAANFKSALARQAQPQSPSAGENQKKKRPVYSQPADTNTQLVYCVDHLKSRLQDIEKFKAHDRVIYNPKSDTYQYKQITNKAQLLTEIQRQGVSIKMLKES-WK--D--AQGAIDELEKEGEVYISRTRKPE-QKVFWNEIKKLWTDLKVPDLLKALAQEGLQATA--KKK-GKRR-ITNTHLKG-EIDLSR Rhior3 --------------------------------------MEQKERRNQL--DSVVSIEKLVNNEKIEYDSVNNMFSYKQIKSKEDLLSLLISKGMDYKDLKDS-YS--K--LSSAVEELAGEGVILVVRNKDGN-PRLFYNDAQKMWSEISIPDLPKALEEAGLKTMEPKRSK-TRHK-ITNTHLSH--IDLSK Rhoto1 ----------------YDTSSST---------------QTQLALSVAFLKQRLEDLEGLKKHERVRYTEKTGLFAYKILSSKNDLLILLRRHGLPVKKLRES-WA--G--VTTAIEELEREGRVLVTRTREGQ-MKVFLD---DLWRSLKTPELAQELKNAGLTASSKAKAK-GRKK-ITNVHLKDQGIDLSK Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ANLNAFKSKVKSAASERAQENTLSPSKKVRAAAALQ-ASSKLLWATEYIQKLVNELELLKKLDRIEFDPKKGTFKYLDVHSPSELLKLLRSQGISCKDLKDG-WP--Q--CDETINQLEEDSKILVLRTKDKT-PRVWYNSGGKMWENVQLPELPRKLQDLGLKPASEVKKK-RQRK-ITNTHMTG--I--LK Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 ADAAAFKQSLHRT-ASAAPAKGGGAKKKAAPYSQPKDTNTQLIYALQYLKERLQDIEKFRNHEKVKWDQKTGLYEYKAVRNREQLLTEIKRYGISIRTLKDA-WK--E--APTHIEELEKEGKVYVLRTKDGQ-MKVFWNEMSDMWAELKAPDMIRQLVAAEMKPVS--GKK-GQKK-ITNTHLKG-EIDLSR Schpo1 DQLSSFKKKVANQNSNDGHSSAASLKKKRSVYSQPADSLSQLHYAVEYLKETAEEINLLKKNNRIYYDERNETFTFKNIRSGAGLLAYLDSQGMSIKELRDG-WP--N--VTVELEELEKQGEVLLLRTKDGV-PKVWRNDKSQVWHEIPIPDLASELGKYGLKPTSKQKKP-KTRK-ITNTHL-N--I--LR Sorma RQQASFMSSMSAAPPSPSPSVGSADRVDTPVYSQPAATITQVTYAIAWLRGTYLEIEAMRRTREIQWIPDSGTYLHRGVRNKTQLLAYLQKKCVGVKELKDG-WP--D--CEKAINELEAEHKILVIRIKEGL-PRVWLDDPSVMWQKVEVPTIVQRLKAASQKPASEKKKR-AQRK-ATNTHMEH--L--LK Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ESKAALKKRMLATASHPPPPQ--QAKRKLPIHAD----NTKVYTIINALRESEKEIEILRNNLKIEFIPQDKTYRYKTIRSKEDLITLLQSHGMEIKELLDS-WS--G--LLGAVQELEKEGHVLVLKTKDQK-PRVYWNDKSNYWHEIQLPDLAKELERAGLKSMEKESKR-RSHK-LTNTHLEG--LDILG Sporo1 ------------------PSLTG---------------QTQLVLAVNFLKQRLEDLQALKQHDRVRYEPRTELFQYKLLSSKSDLLSLLRRYGLAIKPLRES-WP--G--VTQAIEELEQEGRVLVTRTK-GQ-MKVFLD---DLWHSLKTPDLVTELQTAGLTSSSKKGGK-GKKK-ITNTHLKE--VDLSK Stehi1 RDAAAFKNTLQSVSQAPLPPPSTGKKKKRPVYSQPADTNTQLLYAVNHLKSRLQDIEKFKAHDRVEHDPKTNLYSFRSFRNKAALLTEIQRAGLSVRTLKES-WK--E--APAAIEELEKDNEVYVTRTKDGQ-MRVFWNEVKDLWHKLKVPDLLKELASEGLQATA--KKK-GKKK-LTNTHLRDMGIDLSK Tapde11 ASAAAFKKQAKTAQQQPKPDPIDPAKKKTKIYSQPDALITNMHYAMQYLKRTSAELHILRKNERIHYDSQTDTYSFRNVRSAPQLLALLEAQGLSVKDLREG-WP--N--CIEELDRLEKEGKILLIRQKDDR-PRVWKSNIEDIFRKVVVPQLPRELQSLGLKPTSTKQKK-PNKK-VTNTHMSG-----LK Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ---------------------------------------------------SQHDAERIRQLDKIEVNSVNGSMSYKEITNLTQLRTYIRTHPVSLRLLREATQP--SSFSLNPLTEMETRGEILIMRSRDAPLPRVWWDELKWAWDEVEIGDVGKLLEDAEVGRVGGKKKK-KKNK-ITNTHMIEHGIDFTK Trire2 KQSSVFRGSLASAPPSPSPSAASAKRKRDAPFSQPQLTKTQMTFAVEYLKKTIQDIEGLRRHPRVEWRPDTGTYKHRGVKDATSLLAHLQRKGVSVKDLKDG-WP--D--CEETLAKLEREHKVLVVRTKDNF-PRVWADDPSAMWRRVQLPDMHRKLVSVGQKPTSQQKKR-AGKK-ATNTHMTH--L--LN Umbra1 DQLKSFRKSLASQPGTPAIANNTSMEGKKKVFSQPANTMSLLYTVVNYLKNSVVSIEKLTTNEKIDYDEINGTFSYKQIKNKDDLLQLLQEKGMDYKDLKDS-YS--K--LGVAVEELAAAGQILVIRHKDGN-PRLFCNDEQKMWTEISIPDLPRELENAGLKTMEQKKSK-NRSK-ITNTHLQN--LDLTV Ustma22 -----------------EPS----------IYSQPANTNTQLASAIDALKHRLEDFQRFRSHDRVTYDAKTDLYMYKDLRTPADLVALLKERGMRLAELRES-YP--A--ARDAIEELGKVEEVLILRGRDGA-IKVFWNPLRELWHELKVPDLPKELEREGLSTTD-KNKK-KKKK-LQNTHLEG--VDLSQ Walse1 -------------SVAPTPGPSGQAAAKRKIYSQPRDTNSQLAYLVQFIKDRLEDLDLFNSHDRVQHDTKLDLYSYRPMKSKAELLKHVKGYGMRVNLLKES-WS--G--APAAIDELERENEIVVLR-KDGQGMRVFENNVKGLWHSLNVPEVARDLDDAGLKRTS---KK-GRQN-YIYTH-----IALHR Zygro1 ANLNAFKSKVKSSGSQ-----TDS-NKKVRAAAALQ-ASSKLLWATEYIQKQLNELELLKKLDKIGYDPKKATFKYIDVHSAQELLNLLRSQGISCKELKDG-WP--Q--CDETINELEEDSKILVLRTKDRT-PRVWYNNGPLMWENVQLPELPRKLQDLGLKPASEVKKK-RQRK-ITNTHMAG--V--LK [Cluster3096.fasta_al_trimmed; alignment length = 83] Allma1 RR-AYATFIPPNVAAQPAASTGAELKPLVSLYRGLPKGNAPVGYRNKHFQNGKESGAPLAHVILLVFGVGYTMA--YHKNQAH Ashgo11 KR-ALSTLIPPKIVSPKNLTSAKRIANVVELYKALPQGPAPGKYRAKYFDGDNASGKPIVHFAIFVLCLGYSMD--YHKGEGH Aspfu1 RR-GLSTLIPPKIASPNAIGAAARMERVVNFYARLPRGSAPGRYQARYF-GKNPSAAPLAHAIGGILLIGYSME--YHKNHPH Aurde31 RR-ALSNLVPPKIATPNSVS-GASLAPLVEFYSKLPKGPAP---KARYVDGKNASGAPLLWGILAIFGLGYTID--YHKNHPH Batde5 YR-TLSALIPPNVSSMRELGRPEIFARMTAFYKAVPKGQANGKYYEKYV--ENDSLYPILHVIGVMIPIGFYIQ--YHPSREF Botbo1 RR-TLGTLIPPKVATPAAVT-GAAMARVVDFYSKLPKGPAP---KARFFDGKNASGGPLVVAMLTLFGFGYTID--YHKNHHH Botci1 RR-ALSTLIP-----PKGLGAAARMQRVVSFYEKLPRGPAPGRYQAKYF-GKNPSATPIIHALIFLVGIGYAQN--YHKNNAH Caeel ----------------------------------------------------------------------------------- Canalb1 RR-QLSTLIPPKIASAKNLGSAKRMAEVVKFYNKLPQGPAPARYRAAYFDGDNASGKPLVHLAIAVVIFGYSLE--YHEGH-- Cangl KR-AVSTLIPPKVVSAQQLGAAKRIANVVSFYKSLPQGPATGKYKSKYYDGENASGKPIWHLSLAVITFGYSLE--YHKDH-- Capow ----------------------------------------------------------------------------------- Catan2 RR-AYSTFIPPNVAATPAAG-GAELKPIVSLYRNLPKGNATVNYRNKHFQNGKETGAPLVHVILLVFGVGYTMA--YHKNQEH Cioin ----------------------------------------------------------------------------------- CocheC53 KR-GLSTLIPPKIASPNAIGSAVRMQKVVNFYEKLPRGPAPGRYAKKHM-GKNPSGRPLVHVIGFLIALGYAQN--YHKNNEH Coere1 GRSALKSIIPPNIGFAARAGEAPQVDKVVSLYRNLPKGPAGARYYARYIEGDNASAAPVAHVIGALLVGGYSIH--YHKHAEN Conco1 ------SFIPPSLATKQGASGTEGLGDLVHIYRQLPKGPASEWYRRRYFEGPNASPAPILHIMIALGLLGYYIE--YHK---- Conpu1 RR-SLGGLVPPKIATPSHLS-GAALNPLVNFYSKLPKGPAP---KARFFNGKNASGAPLVWTILGIFGLGYTID--YHKNHAH Copci RR-SLGGLVPPKIATPKLVS-GASLGPLVDFYSKLPKGKAT---KAKFFDGKNASGAPLVWLIVGLFGIGYTLD--Y------ Croqu1 AS-ALRNLIPPKIASVQALTTAARMQRVVDFYSKLPQGPAPARYKARYIDGENASGAPLLHAIIGLFVIGYTIE--YHKNNHH CryneH991 RR-SLAGLIPPKIATPGAVSSSARTAQVIDFYSKLPKGPKP---KGRFFEGKNASGAPVVATLAALFLIGYTID--YHKHGHH Crypa2 RR-ALSTLIPPKVASPKAIGSAIAMKRVVNFYEKLPRGPAPGRYQAKHF-GKNPTAKPIIHVIVFLVAVGYAQN--YHKNNAH Debha1 RR-QLSTLIPPKIASAKNIGSAKRMTDVVSFYKKLPSGPAPGKYKAAYFEGDNASGKPLLHLALIVGILGYTWE--YHKGH-- Dekbr2 RR-SLSTLIPPKIASPANLGSAKRMQNIVSFYSKLPRGHAPAKYREKYRN----TGKPVFHVTMALLISGYALN--YEKGEEG Dicdi ----------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------- Fomme1 RR-QLGSLIPPKIATPKLLTGGGGLAPLVEFYSKLPKGPAS---RGRYYEGANASGKPLVFTILAIFGLGYTID--YHKNHAH Fusgr1 RR-ALSTLIPPKVASPKAIGAAIRMQRVVSFYEKLPRGAAPGRYQAKHF-GKNPTAKPIIHLIVFLVGIGYAQN--YHKNNAH Galma1 RR-QLGGLIPPKIATPKLVS-GAGLGPLVNFYSKLPKGEAT---KGRYFAGANASGKPIVAVILSLFAIGYTLD--YHKNHAH Ganpr1 ---------------------------MKDFYTRVAKGPAPELYVRKYMTRGQESGVPLLHLLLLIIPTGYIIKSGYHPNREF Gloin1 ---AIKSLLPPKISVSGVTGATAALS---DLYSKLPKGPAPGRYYARYI--ATSSPAPILHVTLAIGFISYAFN--YHKTKEH Hisca1 RR-GLSTLIPPKVASPTGIGAAARMERIVGFYEKLPRGPAPGRYQARYF-GKNPSAMPILHVIGGLMFMGYSME--YHKNNAH Klula1 KR-ALSTLIPPKIVSANNLGSAKRIANVVSFYKSLPQGEAAGRYKAKFFDGENASGKPLLHLAIGILTLGYSME--YHKGGEH Lacbi2 RR-QLGGLVPPKIATPKLVS-GASLGPLVEFYSKLPKGEAT---KGRFFTGKNASGTPLVALIVGLFGIGYTID--YQKNHAH Lenti61 RR-QLGGLVPPKIATPSILS-GAGLGPLVNFYSKLPKGPAP---KGRFFNGKNASAAPVLFTILAIFGLGYTID--YCR---- Malgl1 AR-AFSPPIPPKIATPKSVQ-AANTEAVVNFYKALPKGSEP---KAKYFDGKNASGKPLLWVIGGLMLFGYTLE--YHS---- Mellp23 SS-SLRTLIPPKIASVQALTGAARMNRVVEFYSKLPKGSAPARYKARYIDGENASAAPLLHAILGLFVVGYTIE--YHKNNHH Mnele ----------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------- Morel2 RR-AYSTAIPPTI-GSTKAIGAARMAKVVNFYKGLPNGPAP--YQARHFDGKNSDMTPVFQTIAAVFALSYTID--YHKNVAH Mucci2 RR-AYTTLIPPNVAAATRLSG-GQISQLVSFYKKLPKGTVEGRYKARYIDGENASVTPLIHLIFGVFAIGYTID--YHKNVEH Mydma ----------------------------------------------------------------------------------- Neucr2 RR-ALSTLIPPKVASPKAIGAAVVMKRVVSFYEKLPRGPAPGKYQAKHF-GKNPSAKPIVHAIVGLLIVGYAQN--YHKNHAH Orpsp11 ----------------------------------------------------------------------------------- Pench1 RR-GLSTLIP-----PKAIGAAARMERVVTFYAGLPRGPAAGRYQARYFSGKNASGVPLVHAIGGILILGYSME--YSRDITN Phybl2 RR-AYTTLIPPNLAASTKTTG-AQISQLVNFYKKLPKGAAQGHYKARYIDGDNASMTPMFHALFGIFVIGYSID--YHKNVEH Picst3 RR-QLSTLIPPKIASAKNLGSAKRMAEVVSFYKKLPTGPAPARYRAAFFDGDNASGKPLIHLVLAVVILGYTWE--YHKH--- Plicr1 RR-QLGGIVPPKIATPSHLS-ASSLTPLVDFYSKLPKGRAT---KGRFFNGKNASPAPLFATIGGLFLIGYTID--YHKNHAH Polpo ----------------------------------------------------------------------------------- Pucgr2 ----------------------------------------------------------------------------------- Punst1 RR-QLGGLVPPKVASPTILS-GASLSPLVEFYSKLPKGSAS---KGRFFNGKNASGAPLVWTILGIFTLGYTID--YHKNHAH Rhior3 RR-AYSTLIPPNVAAATKVSG-ANITRLVSFYKTLPKGTVEGHYKARYIDGENASVTPLLHLIFGVFAIGYTID--YHKNVEH Rhoto1 MS-RLAALIPPKLASPSAIGAAARMAKVVEFYSALPKGPAPARYKARYFDGPNASAAPFLHVIGGLFLLGYTID--YHKK--- Rozal11 ----------------------------------------------------------------------------------- Sacce1 KR-AVSTLIPPKVVSSKNIGSAKRIANVVHFYKSLPQGPAPARYKAKYFDGDNASGKPLWHFALGIIAFGYSME--YHKGAEE Salro ----------------------------------------------------------------------------------- Schco3 RA-QLGGLVPPKIASPNLVS-GAALRPLVAFYSKLPKGEAT---K-KYFVGRNATAKPLLALIVGLWTIGYTID--YHKNHPH Schpo1 ---PLKSFIPPQVANPTALNASARMGRIVDFYSRLPHGPAPSWYYKKYL-GKNASGAPLLHLVGAVLVFSYASE--YHEEH-- Sorma RR-ALSTLIPPKVASPKALGGAVAMKRVVSFYEKLPRGPAPGKYQAKHF-GKNPTAK--------------------HKNNAH Sphar ----------------------------------------------------------------------------------- Spipu1 LR--VSALIPPNVASLKELGKPDIFKKMKYFYQHIPKGNRQGRYYERYI--AKDSFVPVLHFLGVMIPVGYYIS--YHPRFEF Sporo1 MS-RLAALVPPKIASPSAIGAAARMTRVVDFYSKLPKGAAPSRYKAKYFDGPDASAAPFLHAIGGLFLIGYTID--YHKK--- Stehi1 RRQQLGGLVPPKIASPTILS-GGDLTPLVNFYGKLPKGRAP---KARFFNGKNASAAPIAWMMLGIFGIGYTLD--YHKNHAH Tapde11 ----------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------- Treme1 RR-SLAGLIPPKIATPSAVSSSARTAAVIDFYSKLPKGPRP---RGRYFEGKNASGAPILATIFILFGIGYTID--YHKNGHH Trire2 RR-ALSTLIPPKIASPKAIGAALRMQRVVSFYEKLPRGAAPGRYQAKYF-GKNASATPIVHALLFLIGIGYAQN--YHKNNAH Umbra1 RR-AYATLIPPNLAASRAAGGAARMGELVSFYKNLPKGTAPGRYKAKYFDGENSSATPVVHAILLIGGISYAID--YQERGTP Ustma22 LR-QAGPPIPPKIATPKSASGSARMESVVGFYKSLPKGDAP---KARYFDGKNASGKPIVATLFTMFLIGYSID--YHKNNHH Walse1 RRQALKDLVPPKIATPSAVSGGARMSSVIDFYSKLPKGNAT---KGKYFDGQNSSRTPLLATIGGLFLIGYTLD--CHKNNHH Zygro1 RR-SLSTLIPPKVVSSQNIGSAKRIGNVVQFYKSLPQGPAPSKYKAKYFDGDNASGKPLWHLAVSILVMGYSLE--YSKNGEH [Cluster3097.fasta_al_trimmed; alignment length = 181] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ARYGKDNVRVYKVHREMTICVLLEGE-IETSYTKADNSVIVATDSILAKQHELFGSILGTHFIKY-KHIHAARWTRMHPHSFVRDSIKSSITGLTVLKSTGSQFHGFLRDEYTTLKETWDRILSTDVDASWAREITLKTFADNSASVQATMYKMSEQILVEYSLPNAEVYAPGLIKCTVGR Aurde31 ARYGKSNVRVLRVAREYVVQLLVEGD-IDTSYTKADNSCVVATDSALAKTSELFGVHLGVFMLKY-AHLRRAKWTRIHSHAFVRDGVTSGLKDLLVLKSTGSAFEGFVRDEYTTLVEVSDRILSTAVDLSYAREITLDVFADESASVQASLFKMAARLIASYALPNAEVFCPGLITATASR Batde5 QQYGKDKVRLVKVTDELTCRVLLAGAQFETSYTKADNRLVVPTDTYLAQTTESFAKVIGRHFIQY-AHVEEVNWTRIHPHSFYRAGIASGISDLYVLKSSGSSFEDYHLDKLTTLPPMSERVLSTDITATWIKQITLDLFAHNSPSVQNTLYRMGELVLITYELPNSTVYYPGLITATISR Botbo1 ARYGKSNVRVFRVAREFNVNAHLEGD-IAKSYTEADNSVVVATDSILSKTSTLYALHVGLHFVKY-DHIHKSRWSRIHKHAFVRDGITAGYRDLLVLKSSGSAFEGFIRDEYTTLTEVSDRIFSTAIDLSYARRVTLEVFADESASVQATLYKAAQRLLVTYRLPNAEVFCLGYISATVTR Botci1 ARYGKDNVRVYKVDREMTVCVLLEGA-IDVSYTKADNSVVVATDSIKAKEHELFASILGTHFITY-PHLTAARWTRMHPHSFYRDGIRSGIVGLLVLKSTGSQFHGFVRDEYTTLPEVWDRILSTDVDCGWARNITMKTFAENSPSVQNTMYKMCGSILVDYSLPNAEVYAPGLINVTVTR Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 STYGKGNVKFLKVKKEANVQVLLRGK-FDESYTKADNSSIVPTDTVEAKTTERFAAHLAKHFTKY-GHVDGIKWSKIHAHSFKHEGLSSSIKDLTVLKSTGSMFYGYNVCDYTTLQPTKDRILSTDVDASWARDVTLELFCENSPSVQSTMYNMSHKILVSYVLPNKDLFYPGLIKSTVGR Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow RMYGKADVRLLHVRRELRCRVLMRL-ASEIDFVTGDNRDIVATDTALAKKVEQFALAISKHYFQY-KHIEAMRWTRVHSHAFINARLTSGIKELEIMKTTQSGFEGYIKDEYTTLKPTADRVFRTVVSCQYARDAILSEFAVYSPSVQNTIYLAQKRIIVTIEMPNNEVFVVGLIRASMSR Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ARYGKDNVRLYKVDKEQTVRILLEGD-IEQSYTKADNSVVVATDTILAKQHEQFAAIIGDHFITY-PHIHAARWTRMHPHSFYRDGIRSKIEKLLVLKSTGSAFHGFHRDEYTRLPETWDRILSTEIEAGWARDITMKVFADDSASVQATMYKMCDLILVDYSLPNATVLAPGLIQCTVTR Coere1 QAYGKDRVRVVRVVRDYWVCCLLSGEQFESSYTKGDNKLVVATDSYLAKTLEVFATEVASFMVKY-AHVTTCPWERMHPHSFYREGVNSGFYDLEVLKTTNSSFVDFWRDELTTLPDMPDRILSTKVLCQWVKRNTLDVFADPRAWVQSALYIMADRTLVYYALPNAEVYMPGYITATVSR Conco1 QEYGKQNVRFVKVFKEYTVTVLLSGPRFTASYTEADNND---------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 AQYGKDLVRVLRVVREYNVCVLLEGD-IASSYTQADNSVVVATDSYLAKVSEHFALHLGTHIVKY-AHIHRARWSRIHPHAFWRDGVSAGLVDLLVLKSTGSAFTGFVRDEYTTLTEVDDRIFSTSVDLSYARTATLDIFADESASVQATLYKMGQRVIVSYKLPNAEVFVPGLIAATIAR Copci ARYGKTSVRVFRIVREYNVETLLEGD-IETSYTEADNSVVVATDSYLAKVSEKFALHIGTFFVKY-AHIHKARWKRIHPHSFYRDGVSSGLVDLLVLKSSGSAFENFWTDEYTTLVPVDDRIFSTSVDLSYTRDATLQIFADESASVQATLYKMAQRIIVTYTLPNASTSVPPLPNVHVSR Croqu1 AKYGKEKVRVFRVVREYTVSVLLEGE-IQSSYTQANNAVVVATDSVFAKTSELFALHLGLHFVTY-KHITQARWTRIHPHAFSRDGLVSGLKDLLVLKTKGSGFENFIRDDWTTLPEVSDRILSTSIECR-VREITLETFADESASVQATLYKMAESIIVFYSLPNAEVFVPGLITATVSR CryneH991 ACYGKDLVKVARVVREYTLRVLLEGE-IEASYTKADNSCVVATDTVFAKTSPVFALHLGLHFVKY-KHIHKCKWSRIHKWSFVRDGLKIGIKDLLVLKTSGSAFENFHRDENTTLADVADRIFSTSVSVQCILKDVLDTFADESASVQATLYLTLQKILASMQLPNAEVFYPGYITATVTR Crypa2 ARYGKDNVRVYKVHREMTVTCLLEGE-IETSYTKADNSVVVATDSIKAKEHELFASILGQHFITY-AHIHTARWTRMHPHSFYRDGLRSGIVGLTVLKSTGSAFHGFVRDEFTTLGETWDRILSTDVDCGWAREITMKTFADESPSVQNTMYKMCELILADYSLPNAEVYAPGLIKCEVSR Debha1 SSYGKGNVKFLKVKKEANVQVLLKGN-FDVSYTKADNAPIVPTDTIEAKTTERFAAHLAKHFTKY-AHVSGIKWTKYHPHSFKHEGITSSIKDLTVLKSTGSMFYGYNVCDYTTLKPTKDRILSTDVDASWARKVTLDLFAENSASVQATMYNMSHKILVSYALPNDELFYPGLIKSTVGR Dekbr2 CTYGKNNVRFLKVKREASVRVMLTGA-FDVSYTKADNSVIIPTDTVEAKQTERFAAHLVKHFFKY-SWIAGIKWSKYQPHSFVKNGLTGGVQGLTVLKSSGSMFHGYNVCDYTTLKPVNERILSTDVDCKYALKITLDRFAENSASVQATMYNMGTDIVVSYALPNNEMFYPGLIKCTVGR Dicdi R-YGKARVRVLRVFKDFDCRVLLRGAEFSETYLTGDNSKVVATDTVIAQKEEEYGILLGKHFLTY-SWVNGVQWRRIQAHSFQRDRVVSGIDDLLIMKTTQSGFEGFHRDKYTSLKETKDRVFATVVTANWFKLSVFDIFATYSRSVQETLFLIAKDVIVHLSLPNQTVFQPGLIEGTIKR Dmel HGYGKDAVKVLHVSREFEVGTHLKLY-SKKDYYQGNNSDIVATDSLLAKKHEKFALLLARHFIKY-SHVEEAPWQRVHNHAFIFTPVITGIKGLRVLKTTQSSFVNFVNDEFRSLPDQYDRIFSTVVDCSWVKNIIIRNFAVSSPSVQHTLYLSERQVLISMTMPNNEVFIPGTIYAQLAR Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ARYGKDKVRVLRVVREYEVCALVEGD-ISTSYTQADNSVVVATDSYIAKTSEIFGLHLGAFLLKY-EHLHRARWQRIHPNSFWRDGVTSGIRDLLVLKSTGSAFSGFVRDEFTTLVEVDDRILSTSIDLQYAREITLAIFADESASVQATLFRMATEIIASYALPNAEVFCPGLITASVDR Fusgr1 ARYGKDNVRVCKVDREMTVCCLLEGE-IETSYTQADNSVVVATDSITAKENELYASILGSHFIKY-KHIHVARWARLHPHSFFKDGIKSSLVGLTVLKSTGSAFHGFVRDEYTTLPETWDRIFSTDVDATWARNITLKTFADASASVQATMYKMSDLILVTYSLPNAEVYAPGLIKCEVSR Galma1 ARYGKTKVRVFRIVREYNVEALLEGG-IATSYTEADNSVVVATDSYLAKISEKFALHLGTFFVKY-AHISKARWSRIHPYSFYRDGATCGISDLLVLKSTGSAFENFYRDEYTTLVEVNDRIFSTSVDLTYARTATLETFADESASVQATLYKMGQRIIVTYDLPNAEVFVPGLITATISR Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 QSYGKDQVRLVKVIRELTIRVLLEGD-FADSYTKADNSLIVATDTILAKQSEIFATEIGQHFITY-SHVSKAKWTRMHDHSFLRDGIESGLKDMLVLKTTGSAFYGFLRDKYTTLQETNDRILSTSVDATWIRQITLDTFAHNSSSVQATLYLMAKIALIHYELPNTDIYYPGLITATIAR Hisca1 ARYGKDNVRVYKVHREMTVCVLLEGD-IETSYTKADNSVVVATDSIMAKLHELFASILGSHFTTY-PHIHTARWTRMHPHSFLRDGLTSSISGLSVLKSTNSQFHNFIRDEYTTLPETWDRVLSTNVDANW-----------------------------------AEVYVPGLIKCKVGR Klula1 STYGKDNVKFLKVKKECNVQVLLKGD-FEVSYTEADNTPIVPTDTVHARKFEKFAANLALHFTKY-AHVSGIRWIKYSYHSFIHQGLVTSIKDLTVLKSTGSMFYGYNVCEYTTLKPTTDRILSTDIFASLARDITLDIFAENSPSVQATMYNMATAILVSYELPNNELFYPGLIKCTVGR Lacbi2 ARYGKAKVRVFRIVREYNVEALLEGD-LESSYTEADNSVVVATDSYLAKISEKFALHLGTFFVKY-AHIHKARWARIHPHAFYRDGVSAGISDLLVLKSTGSKFEGFIRDEYTTLVEVDDRIFSTSVDLEYARRATLEVFADESASVQATLYKMAQRIIVTYTLPNAEVFTPGLISATISR Lenti61 ARYGKDKVRVLRVVREYNVTALVEGD-IETSYTKADNSVVVATDSYLAKTSERFALHLGTHLVKY-AHLSKARWQRVHSHSFYRDGVTSGLKDLLVLKSTGSAFEDFVRDEYTTLVEVNDRIFSTSVDLTYTREITLEVFADESASVQATLYKMGQRIIVTYKLPNAEVFVPGLITATISR Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------Q-IHSSYTHADNTVVVATDSVFAKTSELFALHLGLHFLTY-KHINQSRWTRIHPHAFSRDGIRSGMKDLLVLKTTGSSFENFIRDEWTTLPEASDRILSTSIECW-VRAITLETFADESASVQATLYKMCEDIIVFYSLPNAEVFVPGLITATVSR Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 QEYGKDKVRLLKVHKDLTIRCLLSGSSFTTSYTEASNKAVVATDSVLAKTSELFAAELANHFLTY-GWVEGARWARMHNHSFWRDGLKSSIAGLLVLKTTGSSFEDFVRDEYTTLPETKDRILSTCVDSTWVRDVTCDIFADESASVQATLYKMAAKSIVSYALPNADVYQPGLITATVAR Mucci2 ARYGKDLVRLMRVYKELTVRLLLEGD-IETSYTKADNSVVVTTDTIMAKRSEVFGQEITEHVLQY-AHISGAKWTRLHNHSFVRDGITSGLDKLLVLKTTGSAFHGFYTDEYTTLVPVWDRIFSTAVDCKWVKQITCDTFADDSASVQATLYLMQQQILVSYALPNMEVYHPGLITATAAR Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ARYGKDNVRVYKVHKEMTVCCLLEGE-IDTSYTQADNSVIVATDSIKAKEHELYASILGQHFLKY-AHISAARWTRMHPHSFLRDGIKSGIVGLQVLKSTGSAFHGFVRDEFTTLKETWDRILSTDVDAGWARNITLKTFADESASVQNTMYKMCEQILTNYSLPNAEVYAPGLIKCEVSR Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ARYGKDNVRVCKVHREMTVCVLLEGD-IETSYTKADNSVVVATDSITAKQNELFGSILGTHFIKY-SHIHAARWVRMHPHSFIKPGINSAINGLTVLKSTGSQFWGFVRDEYTTLKETWDRILSTDVAANWARAITLKTFADNSASVQATMYKMGEQILVSYALPNAEVYAPGLIKCTVAR Phybl2 ARYGKDLVRIMRVYRELTVRLLLEGA-IETSYTKADNSVVVATDTILAKRSEVFGQEITAHMLQY-THISSAKWSRMHPHSFVRDGITSGLKNLLVLKTTGSAFHGFYKDEYTTLVETWDRIFSTSVDATWVKQITMDTFADESASVQATLYLMQQQILVSYALPNMEVYHPGLITATAAH Picst3 SSYGKANVKFLKVKKEANVQCLLKGD-FDIAYTKADNAPIVPTDTVEAKNTERFAAHLAKHFTKY-SQVHSVRWSKFHPHSFRYDGLTSAIKDLTVLKSTGSMFYGYNVCDYTTLAPTTDRILSTDVYALWARNTTLEMFAEKSASVQATMYNMSHSILVSYELPNKELFYPGLIRSTVGR Plicr1 ARYGKDKVRVLRVVREYNVTALLEGN-IDTSYTQADNSVVVATDSYLAKTSERFALHLGTHLVKY-AHIHKARWTRIHPHSFFRDGVSAGISDLLVLKTTESSFENFVRDEYTTLVEVDDRIFSTSVDLSYARAVTLEVFADNSASVQATLYKMAQRVVVTYALPNAEVFMPGLISATITR Polpo R-YGKAKVRVLKVNKDLDCCVLLQG-QFEETYLTGNNERVVATDSLLAQKEEDFGIIL----------------------------------DLLIMKTTGSGFENFYRDQYTTLPETKDRVFATMVTAEWFKNSVFDIFSQYSKSVQETLYLIGKTAIINLSLPNNNTFQPGLIEGTVKR Pucgr2 ARYGKEKVRVFRVVKEYTISVLLEGQ-IASSYTKADNSVVVATDSVFAKTSELFSLHLGTHFVEY-EHIGKARWSRIHPHAFTRDGLSTGLQDLLVLKTTGSAFENFIRDKWTTLPEASDRILSTSVDCRCVREITLETFADESASVQATLYKMCQLILVSYSLPNAEVFVPGLITATVSR Punst1 ARYGKDLVRVLRVVREYNVRALVEGE-IETSYTKADNSCVVATDSYLAKTSERFALHLATFLVKY-AHLSKSRWTRIHTHSFYRDGVTSGLKGLLVLKTTGSAFENFVRDEYTTLVEVNDRIFSTSIDLTYARNITLEVFADDSASVQATLYIMAQRIIVTYTLPNAEVFTPGLISATVSR Rhior3 ARYGKDLVRLLRVYKELTVRLLLEGD-IETSYTKADNSVVVAT----AKKSELFGQEITKHVLQY-AHISGAKWTRMHNHSFLRDGITSGLQKLLVLKTTGSAFHGFYKDEYTTLVETWDRIFSTSVDAKWVRQITCDTFADDSASVQATLYLMQQQILVSYALPNTSLYYPGLITAVAGR Rhoto1 AKYGKAAVRVSRIVREYIVRCLVEG-DVARAWTHSDNAPIVATDSIFAKTSESFALHLGLHFVKY-AHLNRCKWSRIHKHSFVRDGCQGGITGLLCLKTTESAFEGYVFDEYTTLKPVDDRIFSTAVDCTYVVDTTLEIFAHNSASVQATLYNMCEKVLIKYELPNAEVFTPGHIIGLVTR Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 CAYGKTLVRFMKKDIEMDVQSLLTGE-LEESYTKADNSIVVPTDTVFAKNNEVFAAKLAKHFVKY-KHIHGAPWTRMHSHSFIRNPVVSSLKDVLVLKSTGSGFTNFHKCEFTTLPEVTDRIFSTSIDCNYVKEITLETFADDSESVQATMYKMADTIIVYYALPNCSLYQPGYITCTVAR Sorma ARYGKDNVRVYKVHKEMTVCCLLEGQ-IETSYTEADNSVVVATDSIKAKEHELYASILGQHFLKY-AHITAARWTRMHPHSFLRDGIKSGIVGLQVLKSTGSAFHGFVRDEFTTLKETWDRILSTDVDAGWARNITLKTFADESASVQNTMYKMCEQILTNYSLPNAEVFAPGLIKCEVSR Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 ---GKDKVRVFRVVREYIVKCLVEG-SVEKAWTESDNSSIVATDSVFAKKSETFALDLGLHFVTY-ASRFEAKWSRIHKHSFVRDGCESGIKDLLVLKSTESSFENYVFDDYTTLKPVDDRIFSTSVECTYVVDTTLEIFAHNSASVQATLYIMGEKVLVHYELPNAEVFTPGHIIGVVTR Stehi1 ARYGKDKVRVLRVVREYNVTVLLEGD-IETSYTQADNKVVVATDSYLAKISTRFALHLATHLVKY-PHIHKSRWTRIHTHAFWRDGVEGGLRDLLVLKSTGSAFEDFVRDEYTTLVEVKDRILSTSIDLTYSRDITLDVFADESASVQATLYKIAQTILVRIALPNAEVFQPGLITATISR Tapde11 NRYGKELVKFMKKVVEYTVLILLRGD-FEESYTKEDNASVVPTDTVLAKTTEVFAAIMANHFTRF-AHVSSARWSRIHPHSFYRDGVSSEIRDLQILKTTGSAFYGFFKDEYTTLPEVKDRIFSTNVNCSYARQITFETFADNSCSVQATLYKMCEKIIVEYTLPNATVYLPGHINACIAR Thetr HHYGKSRIRVVHVDRELSVDVYLWGADFARTYLSGDNSTTVPTDTALAKIHESFAESVAQHFKKY-AQVTQCLWERLHKTAFAEAGVVSGFKGLRVLKTTGSGFEGFPRCEYTTLPEMHDRLLCTSVTANWIRNVTLD-FSIRSLSSTTSARRSWSGCL-------TTLRVTSSIRGCDGR Treme1 ARYGKDLVRVCRVVREYTVRVMLEGD-IDTSFTEADNTCVVATDTVLAKTSAMFALHLATHFVKY-KHIHKSRWSRIHKWSFVRDGVKGGIKDLLVLKSGGSAFTNFHRDEYTTLAEVADRLFSTSVTLSYARKDTLEVFADESASVQATLYNTLQKILASMALPNAEVFHPGLITATVTR Trire2 ARYGKDNVRVLKTDREMTVSCLLEGD-IDVSYTKGDNSVVVATDSITAKQNELFAAILGAHFITY-SHIHAARWTRMHPHSFLRDGITSGIEGLTVLKSTGSAFHGFVRDEFTTLPETWDRILSTDVDASWAREITLTRFADESASVQNTMYKMCEQILVIYSLPNAEVYVPGLIKCEVAR Umbra1 ARYGKDKVKVMKVYRELTVALTLEGD-IETSYTEADNSVVVTTDTIMAKRSEVFAQEITEHVLQY-KHIHVAKWSRMHPHSFVRDGIESGLKNLLVLKTTGSAFHSFYRDEYTTLPEVWDRIFSTSVDATWVKKITMDTFADDSASVQATLYKMQQQILIDYALPNLDVFQPGLITATTAR Ustma22 ASYGKDLVRIFRIVREYTVRCLLHGESLTPSYTEADNSPVVATDTYLAKVLERYALNVVNHFLTY-SHIEKTKWTRIHKHSFVRDGLEGGIKGLLVLKSSGSAFYGFHRDSFTTLKEVHDRIFSTEVECSYVKSHVLRVFADDSASVQATMYRMGEAILVSFALPNAEVFLPGYIKAKIAR Walse1 AKYGKDGVKILRIVREYTITVLLEGD-ISASYTEADNSVIVTTDSVFAQNSETFALELGLHFVKY-SHIKKARWTRIHGHSFRRDGLKAGLKDVFLLKSTGSSFNNFINDEFTTLRETDDRVFSTIVDCSYVRNVTLDTFADFSESVQTTLYTMAERIIVSYKLPN-DVLLPGLITATVSR Zygro1 SIYGKDNVKFLKVKKEATVKVLLKGN-FDVSYTEADNSPIVPTDTILAKTNEKFASTLALHFTKY-AHVSGVRWVKFSQHSFVHQGLSTSIKDLTVLKSTNSMFYGYNVCDYTTLKPTEDRVLSTDIYSKWARAITLDIFAENSASVQATMYNMATEILVSYELPNNELFYPGLIKCKVGR [Cluster3102.fasta_al_trimmed; alignment length = 160] Allma1 -VFQNVLRAYQPAWHGAMRLVPPTAKHLRTKE-DRLRERFYRDHPFELVRPQTLVED-YSKLSGEDVIQYQLYLVSQ-GLTINEAYDQAVREFRSIRLQEEAEAKKTKAAKL-------DKNMTSDLELRTFYPEN--YPAWLSEHYILR----QQTMKA Ashgo11 NVLDRTSFYLQPAWYNVVARIPPVTQTAA--E-DKLRSLFFQQHPWELSRPKVLVED-WSRLDGESVVQRTLYLLKS----MLAAYDQARFEFYRLRMQQELEEQIAYEEAT-MVGAVFKTTVEHGLQQEQKVLDK--WKEDVKKNSTKQSW-EEQDSAE Aspfu1 RVRQTALRQHAPKWLDVVADIPPAQPKKASRE-DQLRQEFFRDHPWELARPRVLVED-WSRLDGESVVQRQLWLLNN-DMTKSAAYDIARCEFYRLRLQEDIERRVAAEEAE-ATGATFGPSLEVGMELENQEYER--WKAWAQKTAAFTGA-ADDAV-- Aurde31 QVHKTAGRLLQPAWYEVVLQHPPIPG-----E-DEIRRQFFRDHPFEAFRPRILSEE-WTRATPEDCVQFALNLHAAHGLSLSEAYELAVTQFRALQSERHIAKATARLEAL-TYGASFGPSVEESFQREEANMRT--WDLE-----EWKKGE------- Batde5 KLPDQILNLQTPAWYAAMQLHPPAPKTLSVRE-DEIRRVFYKRHPFELDRARCIVEE-WVDLSGESVVQRTMYLLNQAKSFRSTAYKQALTEFYAAREEEELRKKSLSEMAEKIKGEAVAPVFSDPILGARHKAGS-FWHAEEKQQESKKMMQAQKSAGS Botbo1 QVHQSTSRLLKPAWYQAVLAYPPIPPQKHLRE-DKIRLQFFKDHPFETFRPRSLIEE-WTRPTTEDVIDFAATLHQEHNQPLSEAYKTAVMQFRALRAEFAISSAVARQEAQ-AYGAQFAPNLERGFMNEEKALDT--FVGD-RESKEWTRGA------- Botci1 -------------------------------------------------------------------------------MSNSEAYDIARKEFYALRQEEEIERRIAREEAE-YVGAYFHKGLEVGMELEDKSYED--WKAWAQQQGAYT---DAEAV-- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 NVLQRASAQLKPLWYDIIAKYPPTSKSKNHNE-DSLRKIFYQQHPWELSRPKNLIDD-WSHLDGESVVQRTLWLLKN--LTMVEAYDKARFEFYKLRMSEEMESHVAKEEST-MYGSVFTSTVNWNLSKEQEYIND--WTIIANMNKSSAPIGEQSGQQQ Cangl NVLERTSAYLRPAWYNVVASIPPVTKVANKQE-DKIRTLFYKQHPWELARPKIVSED-WKNLDGENVVQRTLYLLKT----ITDAYDQARLEFYRLRMQQELEEQVAAEEAE-MFGSVFGPSIEHGVTKEQQVIEK--WKRDAKKENASKAAGDESTDAD Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -IFHNVTRMHQPAWVPAMRLVPPSTKHTRAAE-DRLRQRFYRDHPFELVRAQTLVED-YSTLTGEDVIKFQLHLVST-GLTIDEAYEKAVRDFRTVRMEEEAEEKR-RAAEL-TAWQKQAQVFERSHTLKAKNPQN--YEAWLQQAFRLR----LETMKA Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RVRQTAKALFDPQWYDVIGNIPPGEARKASKE-DKLRSEFFGDHPWELARPRLVVED-WSKLDGESVVQRQMWLMKN-SLSKASAYDVARREFYKHRHLSEIRSRIAKEEAL-HVGAYFGKGLEIGMELEDRQWEN--WKAWAMRAQMFSGQ-YDQAI-- Coere1 GVAKAYEKLLSPPWLHAMRSAPPADARLRTKE-DRLRREFYKNHPFEMYRPRILME---WKVTGENVIRYQYYLMQDKGMTREAAYAQATQEFYAFRAREDAESNTAQQEAR-FYGARMLEKSARMLCLEEREIH--------AQEQQIRDTTADSLQPN Conco1 QVIKTTRKLFEPAWFSAAEKYPNNTRKTKFVE-DALRQRFFKDHPFELHRPISLVED-ASRVTVQDVIKYQLHLMSQ-GKTEDEAYAQATKILVHHRVYDEVQTERAKEQAL-Y--------FGAKLEPSVTEKRN-----QLKQKDEIRKAGSEKSFKE Conpu1 QVHKQAARLMRPVWFQAVLDHPPLSR-----E-DEVRRQFFRDHPFESFRAISLVEE-WTRPSAEDAIRFAVNLHQNHDMSLSSAYARAVAQFRSLRAEHEAATSAAKMEAE-AYGTIF-PSTDRSFEKEEKQLYS--EADQ-SGMGGWSRGQ------Q Copci QVHQQVSRLMRPVWFKAVLDNPPLA------E-DDLRRQFFRDHPFEAFRPRTLVEN-WTRPTPEDAIQYALNLYQYHGVSLSEAYARSVAQFRALRSEHHVATVFAVMEAE-ALGGTFAPDVDRTFQKEAEALET--WQLK-DGVDQWTKGE------- Croqu1 LVHNQLSSILKPPAYSALLNYPPAPYRKVVREHDRLRKAFYRDHPFEAYRPVSLVEEHWTEPSAEDCVNFAYALYQHHGYSLNGAYQVAVSQFRTLRFEHHISTSFARQEAE-FFGA---------------------WSQDLTSTGS------------ CryneH991 QVPSAVSRLLQPTWYIPALSHPPPQRGYKQRE-DRVRRQFFKDFPFEALRPVSMVEE-WTSPTVEDCIEFVINLRNTRDLSISEAYALATEEFVSLRGRHQLATLAAEMEGR-HYGAEYKPDFERAFNLEEKALES--LRPL-GGGGGFSAGQALGSSKS Crypa2 -----------------------------------------------------------------------------------------------------------------MVGAYFGKSLQVGMELEDATYDN--WRKWAERESAYA---NKKNLAD Debha1 GVLERTSHYLKPAWFNVVGSHPPMMQQRHNSE-DQLRDVFYHQHPWEFSRPKTLIED-WSHLDGESVVQRTLWLLQD-TMSLFEAYDQARFEFYRLRMEEEMSSTVSKEESS-MYGAIYPSTLDWGIKKEQEYIDA--WTKVANKDGRTANGSEENSNAQ Dekbr2 QVLERTSQYLDPSWYKVLAYHPPMFKQMNKDE-DDIRSLFYRQHPWELADPKVLNED-WSTLDGESVVQRTLYLVRV--MPLYNAYEQSKYEYYRLKIADETESSVTAEQSE-MFGAVYNKSIEYGFDKEMAVLSK--WKKDAKRANSSASGSEESTEED Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 QVHKQVARLARPLWYRAVLEHPPLPATADLRE-DEVRQQFFRDHPFEAFRERSLVEK-WTRPKPEDVVRFTVNLYEHTGLSLSDAYVSACMQYAALRSEQEIASKIALAEAE-FYGITFKPTIERAFQREAEHMKS--WEVK-GGEPMWTRGEEGEEVRV Fusgr1 RVFQTVTEELNP-WYNIMQKVPPAETTKIKNE-DELRGIFYRDHPWELARPRVILED-WSKLTGESVVQYWMWLLENGKWTRVRAYDHVRHQFYRLRQEEQIEKRVAQEEAR-YVGAYFGQTIDVSHGLEDREFEN--WKLWANRNGE-----AEEVIGD Galma1 QVHQQVSRLLRPVWYQAVLDHPPLTH-----E-DDIRRQFFTDHPFEIFRPSTLVED-WTRPTPEDAIRFTLNLYQYHSLTLSEAYAQAVAQFRALRSEHHIATTFAAMEAE-QLGSTFGNSIENTFEREKRSLAS--WERK-HGADQWSKGAEMPDPFA Ganpr1 HVLKYYKPSFHPEWMAAVRLHPPEGRAESLRE-DEIRRRFYEEHPFELLRGTTLGED-WQRATAESAIRHALHLHTRDNLPLSVAYSTAVHAFRLARAREE--AARAKELAE---GQVDADAAPEGVGDSNRTLRE-LFKARPREADRIKKAEGASAAGG Gloin1 QLHNHVSRLFTPVWYSAMKNIPPGQKHLKTKL-DALRKDFYRDHPYELLRPQILIE--FVEVTGENVIKYQEYLIKKKGMSKNDAYIQACNEFYKIRAREEVAERVAEEQAL-LFGARGGQSTERSLWLEHKNLQ-----------QVLRLVS------- Hisca1 RVRRTALATTQQPWLDVLADIPPASSKKPSRE-DQLRKEFFRDHPWELARPRVVLEN-WQNLDGESVVQRQLYLLNN-DMSKGAAYEIARREFYQLRLQEDVERRVAQEEAL-ATGAYFGPDHTVGMELENQEYEK--WKVWAQRLAAFTGSTEEDAIG- Klula1 NVLERTSAYLKPAWYNVIAKVPPTKKDGASKE-DKLRKLFFQQHPWELSRPKILVED-WSHLDGESVVQRTLFLLKS----LIDAYDQARFEFYRLRIQQEIQDQVAQEEAE-MFGSVFHTTIEYGIAKEQKVIDT--WKRKARASSPSASW-QKPIDQD Lacbi2 QVHQQASRLLRPVWFRAVLDNPPLP------E-DEIRRQFFRDHPFEAFRPTTLIEA-WSRPKPEDAVQFALNLYNHHDIPLSEAYARAVAQFRSLRSEHHVATTFAVMEAE-ELGAVFLPTIEHGFEKEKRALGT--WERT-NGVDQWTKGQ--PSSMG Lenti61 KVHKQASRLLRPAWYRAVLNHPPLPK-----E-DEVRRQFFRDHPFEAFRQTTLVEE-WTRPTAEDAIRYAVNLYEHHGMDLSSAYASAVAQFRSLRSELLVARAVAQTEAE-QLGMEFGPSVEITFAKEEKAFHT--LRED-GPPEQWTRGQAQRVAAS Malgl1 -------------------------------------------------------------------------------MSLSQAYRRTIASFHAVQAEREQRLRFAILEAR-NYGADFSLSTERGFAKEAQELDK--WAVT-RADDSFFAGATQETASS Mellp23 LVHNQLSSFLKPPSYSALLNYPPTPFKKLIKEHDLIRKAFFKDHPFEAYRPINLIE-------------------------------------------------------------------------------------------------------- Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KVHSYVTKLLKPVWYPAASLAPPSPKHLRWKE-DKLRRRFYEDHPWELRRPRCLIED-GTRLTGEDVIQYQLYLMTT-GKSEREAYHIATEEFYLHRAQEETEARVAKAQAM-A--------FG--LKPRRSFVMN-----GL-----------EAALRE Mucci2 GLAKHVSNMLKPVWLSVVQAIPPGPKHLRTPE-DKLRRQFFKDHPFELSRPKVLVED-FSKIDGEAVIKYQLYLMTHEKMPERKAYAKATSEFYEIRAQQEEDERAARAKMNNVLQTLQSKKTQKALYLEER--------------SQF----------- Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 KVYQRASEAAAPLWLKAIESIPPAE-RKPRNE-DELRRDFYRDHPWELARPRMIIED-WSKLSGESVVQRQLWLMEN--MTKQEAYDKARHEFYKLRQLEQMERRIAVEEAR-MVGGYFGKDLTVGMELENKTYES--WKKWAARASMYT---EDELLAQ Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 RVRQTALNQFAPQWVGVVGEIPPAEPKKPSRE-DQLRTQFFRDHPWELARPRVLLED-WSRLDGESVVQRQLWLLNN-DMTKSAAYDIARREFYRLRLKEDIQRRVAAEEAA-AYGAEFGPSLDIGMKMENEQYDK--WVAWAQRKSALSGA---DTT-- Phybl2 GLARHVSNLLKPVWLPVLQSIPPGPKHLRTKE-DKLRRQFYRDHPYELARPKVLVED-FSKVDGEAVVKYQLYLMTHEKMPERKAYAKATSEFYEIRALQEQQERELRKEMFTIVES--SHKSQRALRLEER---------------------------- Picst3 TVLERTSHYLKPAWYDVVGAFPPHTLQKNNSE-DELRDVFYHQHPWEFSRPKTLIED-WSHLDGESVVQRTLWLLAD-KLSLFEAYDKARFEFYRLRMREEMNSSVSREESV-MYGAVFPTTLEWGVQKEQEYIDV--WAKVANRGRGTSAGSEK----- Plicr1 QVHRQMARLMRPVWYQAVIDNPPLPR-----E-DDLRRQFFRDHPFETFRPAVLVEK-WLRPKPEDAIRFALNLYEHQDVSLSVAYKIAVAQFRALRSEHHIASITAAMEAE-MYSAEFGPTTEEMYQAERKALEA--WKTK-GGVSGWTKGE------- Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LVHKQISAQLQPRSYPALVNYPPNPKKKNLEVKDRLRKAFFRDHPFEAYRPISLVED---RPSAEDCIDFAERLY--HGYNLNQAYKIAVSEFRTLRFEEQIRASFARQEAE-YYGA-----EPSQAPLESNKNEEQVWGRDLSSSSSSKPTD------- Punst1 QVHKQAARLMKPAWYGAVLDHPPLPHALGTSE-DQVRRQFFRDHPFEAFRETTLVEE-WTRPKPEDAVKFAVSIHQHHNVSLTQAYAAAVAQFRALRAEQTIATSVAAMEAE-SYGARFGHTTERGFLQEEEHLKS--FESR-GGEGQWTRGKAEAVAAS Rhior3 KIAKHVSSLLKPVWLPVVQSIPPGPKHLRTPE-DKLRKQFYKDHPFELARPKVLVED-FSKIDGEA---------------------------------------------------------------------------------------------- Rhoto1 NIPHAIGRQLKPASFYPILAHPPPPKQKQERE-DKIRRLFFLDHPYEAYRPTTLVEE-WTEPTPEDCISFISNLIEHH-MPLSKAYPHGVAQFRTLRAEQETANRSARLEAQ-AHGATF-FGVEKQIRIQEKVLDE--W----QQAQESKWGD----TGG Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 NVLQRTSAYLKPAWYNVVASIPPSTRVGVKRE-DRLRSLFYKQHPWELSRPKILVED-WSHLDGESVIQRTMYLIKT----MVEAYDHARYEFYALRMQEETEQQVALEEAE-MFGSLFGVSIEHGIQKEQEVLDV--WEKKVRTSNPAGSW-ESTTS-- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 QVHKQAARLMRPKWYQSVLAFPPLPKQ----E-DDIRRQFFRDHPFETFRPTTLVEM-WTRPRAEDAVQFALNLYVHHDLPLSEAYRRSVAQFRALRGERQTAVQVAALEAR-SLGAIFGHSIEHVFEKMKRGLAG--WQRA-EGTVEWTRGEQAASAPT Schpo1 ----NANGLLRSLWYETVAKHPPTFKRLRKSE-DKLRKRFYRDHPWELARPQIIAED-WSHLSGESVVQRTLWLIEN--MPVENAYDQARKEFYHLRAEQEIQQRVAHDQAQ-ALGAVFTKSLELGYEMDQNALNS--WFDNA---SQYA---SKTTQ-- Sorma KVYQRAADAAAPLWLKALESIPPAE-RKPKNE-DELRRDFYRDHPWELARPRMIIEN-WAKLSGESVVQRQLWLMEN--MTKQEAYDKARHEFYKLRQLEQMERRIAVEEAR-MVGGYFGKDLHVGMELEDQAYEN--WKKWAARSSAYA---EDELIAQ Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ALLKNIDRLHAPPWYDAVRRHPPAT--LTYRE-DEIRAAFYRWHPLELARPISLVRD-WKDVTGESVVQHTLYLMTH-NQSRHTAYQNALSAFYKARVEIEER-RAAQQAAQKAAEELLADELDD----KQRAVAE-FWSTRPDAKQARRDLQESDKTDL Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 QVHQQASRLLKPAWYRAVLDNPPLPP-----E-DEVRRQFFRDHSFETFRPVSLVEI-WTRPSPETAVRFAVNLHVHHSFPLTEAYSTAIGQFRALRSEQHIATAFAAQEAE-AYGALFGPSVQRGFAKEERVFAK--NKMKQGHIGEWSKGEKYDIAAS Tapde11 RVAQTTSQLLQPLWLPTVSRIPPSSNRKVKRE-DNLRQRFYKEHPWELARPVLLVED-WSKLSGESVVQRQRYLMTT-RLSRDKAYLQACSEFYAIRSHEAIETRIAMEEAL-AYGTKFDKSVEVGLELESRVIAD--WREKAVESSSRG---VDSILGS Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 QVPQTVSRLLQPTWYIPVLSNPPPVKKSSVSE-DQVRLRFFQDFPFEALRPTSLVEL-WERPTVEDCISFTMTL-HERGIPLARAYWRATDEFVELRARHEQATLAAELEAR-HHGAIFKLDFQRAHQQETRSLET--LIPR------FTAGKQMDGVKS Trire2 GVYKAVSQELKP-WFAVMNSVPPSESGKPKKE-DALRTSFYKDHPWELARPRVVLED-WSKLTGESVVQRQLWLMEN-KMSKRKAYDIVRREFYRLRQEEEVEKRIAVEEAR-YVGAYFGKTLDVGMQLEDQEYEN--WKIWARASSE-----EDAAL-- Umbra1 ELSKHVSRLLKPTWFAAVNAVPPGPKNLKTKE-DRLRRQFYKDHPFELQRPKLLVED-FSQVDGEAVIKYQLHLMVTENLTERQAYAKSTSEFYAIRAQEEAEKRLAQSKITNVFEALAAKKTQRTLHHEEKII------------E------------- Ustma22 QVPQTVSRLLEPAWFEAVNNHPPVTKKSRTLE-DRIRQQFFRDHPWEAYRPKTLVEP--KRPSVEDFVACTLAAHRQGGLSLSQAYHNTLSSYHGLKAEHEHATRYAILEAK-YYGADLGKTTQRGFEKEEKALAS--WAAW-RTDETFTSGDAED---A Walse1 EVHSSVSRLLRPAWYAPVLRNLPSLK-----V-DKIRRQFYEDFPFESFRSRSLTEG-WSSPQPEDAIKFCLHLHNNHNISLSLAYIHATNQFSALKAELEVQKQAAIEEAA-AYGASFAPTIERGYELEERFLNS------------------------ Zygro1 NVLERTSAYLRPAWYQVVASVPPTTKPMDSRE-DQLREVFYQQHPWEFSRPKMLVED-WSYLDGESVVQRTIYLLQK----IIDAYDRTRFEFYRLRMQEEIEQQVAQEEAE-MFGSVFSSSIDYGVEQEQRVIDV--WKQKARRASPAESWGGQET--- [Cluster3103.fasta_al_trimmed; alignment length = 226] Allma1 YFAHTRWRPRRQYAALLHESRALLDFATPGFAFALAKLHATYTLGT-GAVGFLFTSVPLH-DVDLLYGRL-F-RLEYLTARRLSPRTLLTVSGASVSTN--RANCFASHDASRIDVGGELYYLANEVSGGLSFG------TLTLNPIMGHVAATYSSHITRGLSAGCRYDYNIHSFESDLAVGVATW-LRVRYGIAL-ALVYQQQWHALHVRL--GL---GIEASY Ashgo11 FERTTSWDRDYSYENITATSDNLLQFEIPSLNLQISNTFNTFELSINGSLSYLYTDCGQQ-RVDLLYGRMYW-PLEAMYCKRLTPQSQLVLKSLLWQRN--APWVFSTNELSTLSLGAEFWLGISNLLPGCSTALRY-CTTLSLNPLFGHISSSYSVKFSPGTTFCSKYDFNVYSIESNLSFGCESV-LKMSSSLRL-RLLWEGKYKGFLVSA--GAAKFGIQIQY Aspfu1 FAEATNWNCDNSYSSLTATAQSLLDFSTPRLRVHLSSFATSYTLGIDGSVSYLYSTVPLK-LARLLNATLHLPPLNALFLRRMSPTMQLSLAVCSLSHD--TGKLFSTDNSSLLSAGAEAYYSPVSSLIGMSTGLRF-STTLVLTPLTGSLSTTYSLRASPNLAFSSRFGFNVYSWESEMVAGCESV-LKIRVDQSV-RLLWEGRVKELLVSA--GVHGVGVSISY Aurde31 YYRQTGWNEDNLYSNLTRSSTAILDFNVPGLHFNISKFKTTYSMNLNGSIGYIFTSCELD-MIELLYGRLYI-PLDALYSTRLSPTLQLLVAAISLQHD--VGRSWSADDGGRFSAGAELYFSAKEKSAGLSTGLRF-TTTAVFNPMLGHISGAYAARVSRDLALCSRFDFNIYSYLSEWTMGAEGV-VKARISTNV-SLMWEGRLNNMLVGL--GVRAMGLELAY Batde5 YYQTIGWNEDKYYTNLDAGPNRILVFPIPGLNFALGKFKSAYCISG-RSAAFMYTSVPV-----ILFGRL-F-ELEGLYSQLLSPQILLTASTLS-----------EKDD-NQCPAC--VYYTAKENSGGVSLGARY-KKTLVANPIMGHLNSAYSTTVLKDMQMATRYSFNMYSFNADVSVGIEQV-LKARLSLEV-ALRFDGRFKDIMYSI--GMQFFGVQIQL Botbo1 YYRATGWNEDNLYTNLTRSSSAILDFTVPGLHFHMSKYKTTWSLNLNGSVGYIFSSCDLD-MVELLYGRFYI-PLDALYCTRLSPTLQAVVASISLQHD--TGRSWSADDGGRWSAGAEFYFSAQEKSAGVSIAGQF-TTTGIFNPMMGHLSAAYAARVSRDVALCSRFDFNVYSYDSEWTMGTEGV-VKARVSTNI-SLMWEGRLRSTLVSL--GVKAIGLEISY Botci1 -------------------------------------------------------------------------------MSRI----------------------------GRFSAGAELYYGTLNKSGGVSVGGRF-ATTLTLNPLMGNISSTYAVKAGKNLSLCSRLDFNVYSYESDLVLGCEGV-LKARIDQNV-GLVWEGRVKELLFTL--GTKALGLELQY Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 FYKSTNWNEDNIYSNITATSQALLDFPIPGFKIDSSSSASSFTLSINGSLAYLYSSIPLD-AIALLYGRMYF-PLEAMIIKRLTKNSQLLIKCVNLQNN--TAKIYSTNEASVVSIGTEIWYAARTMSPGLSAALRY-STTLAINPIVGHVSSTYTVKTSVASTFCSKYDFNVFSYASNLSLGFESV-FKFSTSLNV-KILWEGRLKEFLVST--GVNKLGISFSY Cangl FDSAGRWKRQNSYGEVTQTPRNLIDFKIPAVNLQVSNSYNSLQLSINGSLTYLYTNLDAD-IVQLFYGKIFY-PVEAMMIKRFSPMNQVIVKCLSFQRN--SEKIVSSNDLSSLFFGAEFWLGMISLNPGCSTSLKY-CTTLSWNPLFGHISTTYSAMTSSSSTFCAKYDFNIYSIESNLSFGIESV-FKASTSLRL-KFLWEGEYKNFLLSA--GTLKFGVQIQF Capow ----------GDYSELSRVAEGLLDFSVPGVALGAVKFLRHLSIGVPRFVGFNYVSHP-N-AAV----------VEAMLDHRPSARWRFQASGISFRYA---PNIYTTEEH-EWAVGGEVFYSFSQEAPGLSVGARY-HTATTFSPIPGHVTATYTSDLTQAMVASTRFEYNVHSNEAEFGVGLRPFDLRFRVDTSI-GVLLRARFPHLTLALGAGCRDGGYAG-- Catan2 YFYATAWRPDLQYGSLLRDVRQVLDFATPGLSLSVAKLHSRHSVGS-GSIGFLFTSVPLS-VADLLFSRLPL-RSSPGIRRFLCP------------TN--REKCFSSENAHGWSLGGEVYYLANEVSGGMSLGS--------------HCWVTFPPHTHHGLRLAC------------------T-------------TTTCTATNRIVCRI--RL---ALDPR- Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 FYEASHWNVDSSYGALNASARALLDFDIPGLRMQISSFATSYTLGVDGSVSYLYSSLPLS-VVRLLYGRIFL-PLEALYLRRLTPTRQLRIAAVSLQND--FGKMYSTDSAGRFSAGAELYYGILNKSGGISTGLRF-ATTLTLNPLMGNISSTYAVKAGPNLALCSRFDFNFYSYESELQLGCEGV-LKAKVDQDV-GVLWEGKIKELLFTL--GARSIGVELQY Coere1 FHRKTGWNECNSYATFRRTSGAILDFGIPGLSVSTGRLNSQLVFSAASSIGYMAASRPLD-IISLMVAQMYP-SITGSYVARRSSTSELMVSGVSFQHSTNQPRTFGTNGRGRLSIGGEVYFGAQEASGGISAGIRYRHE---LNPIMGHTSLTWTRQLQPRICAAARYDFNAFSLSSELAVGVESI-AKVRWSDSL-RCLVDTRFSNMVFSM--GLRSFGLQLQW Conco1 YFEKTNWQREHFYSNLTQASRDILEFTIPGIGINLSRFKVTYTSKIITSMGYLFTSKPLQLMLELLYGNIFL-PVEGLYTCQLSSNSQCIISGVSYQTA--TKNSYHTDTK-KWSAGYEVYYSRATKLGGLSIGVRR-ESTLTMNPVMGHLSTSYTNMIHPQLTAGTRYSFNFWSLESDLAAGFEGL-VKVSLGVNL-TTLLSGRYRQLYFTL--GVKGIGIQLDY Conpu1 YYKATGWNEDNLYANITRSSNAILDFTIPGLHFSISKFNTSYSMNLNGSIGYVFTSCDLD-MIELLYGRLYL-PLDALYSARLTPTLQALIAAISLQHD--VGKTYSAEDGGRVSIGAEFYVSAKERSAGVSTGIRF-TTTALFNPMMGHLSAAYAARVSRDLALCSRFDFNVYSYDSEWTMGLEGV-VKARISTSV-SLMWEGRLKQVLVSL--GVKGIGLEVSY Copci YYKATGWNEDNLYANLTRSSNAVLDFTVPGLHFTVSKFKTTYSMTLSGSLGYIFTSCDLD-MLDLLYGRFYL-PLDALYSTRLSPTVQLSVAAISLQHD--VGKTYSAEDSGRVSVGAELYFSAKERSAGVSTGIRF-STTALFNPMLGHIQSAYTARVSRDLALATRFDFNVYSYDSEWTMGAEGV-VKARASTNV-SLMWEGRIRQMLVSL--GVKAIGIEVSY Croqu1 HYKATGWDQDNEYSQLTQPTRALLDFDFVGLHFSTGKFANSASLSLTGSISYLTSGLQST-VVDLIYGRLHL-PLDGLYTKRLSPSLQAMATLVSLSHD--TGRTYSTEDGGRFSAGAEMYFSPRGKSAGVSTGIRF-CTTATLNPIMGQISSAYGTKIGPNLALATRFDFNAFSFESNITFGGESI-MKAKFSPVF-AVMWEGKWRECLIGL--GLKGVFLELQY CryneH991 ----------------------------------------------------------LT-VVELLYSRLHL-PLSGLATTRLTPTLQAHLAFLSLQHD--TGRTYSVQDGGRFSAGGEVYFSAKQRSFGISTGLRF-TTTLLYNPLIGFLSSAYSAQVSPTVALATRFGVNVYSYESDLSVGGEGV-LKARLSGNF-ALLYEARIRNCLVSA--GVKSIGLEVQY Crypa2 FITSSGADKETQYSNLDLTARSLLGFQTPGSRITLSSFGTSY---KDGWISYLYSTHPLN-LLRLVYGRLYL-PLEALLSTRISPQVNLALRAVSASWDDTAGRLASSDGGGRFSAGGEIYYGTLNKSGGLSLGGRF-QTTLTFN-LVGHMSATYAVMAG-DWTLASQFGFNLYSYESNWAVGMEGV-FRCRCDQNV-GLMYEGRYKSLLFSL--GTRGLGLAVQY Debha1 FYKTTNWNEDNIFSNITATSLALLEFPIPGCKVDLSSLASSFTLSINGSLAYLYSSIPLD-AISLLYGRMYF-PLEAMIIKRISPQTQLLIKCINLQKN--APKIYSTNEASVISIGTEIWYAALSMSPGLSTAFRY-STTFACNPILGHISSAYTVKTSVASTFCSKYDFNVFSYASNLSLGFESV-IKLSTSLNL-KLLWKGRCKDFLVTT--GVNRFGISFSY Dekbr2 FSETSGWNDDMSYEQILRTPNNLLQFKIPGFQVSVASSYSSATLRLNGSVSYFYSSNDMS-VIDLLYGKMYF-PLEGMIVKRLSDSTQMTLRFINLQRQ--NDHIYSSTESTSLSAGFELWFALLSMSPGLSTAVRY-STTLALNPLLGTIESTYSIKPGLNSTFCSKYTFNIYSYESDFLLGFSSA-FKCAASVAV-KFAWEGRFKDLLLSS--GVDKCGLEIQY Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 YYQATGWNEDNLFSNLTRSSDALLDFSVPGLQFSISKFRTTYTLNLNGSVGYIFSTCELD-VVELLSGLLYI-PLDAFYTTRWSRTTQLSAACILLQHD--TGRTWQAESGGRLSAGAELYLST-EKSAGVSAGIRF-TTTATFTPITGHLSAAYAAKVSRDLALCSRFTFNINSYESEWTMGGEGV-VKARLSTSM-AFMWEGRIRNALVSF--GVTAIGLELAY Fusgr1 FYEATGWNRDNSYAALNVTSDALLNFQTPGLRLTLSSFATSYQLGVDGSISYLFSSVPLE-LLRLLYGRLYL-PLEALVVKRLSPALQVQLSAVSAQYD--VGKLASSDGGGRFSTGGEIYYGTLNKSGGISVGTRF-ATTLTLNPLMGNISASYAVVAGRHCSLATRMEFNAFSYESTWAIGMEGV-LKTRMDQNI-GVLWEGRVKSLLFSL--GSRTLGLEIQF Galma1 YYKATGWNEDNLYANLTRSSSALLDFTVPGLHFSVSKFKTTYAMTLQGSVGYIFTSCDLD-MIELLYGRFFL-PLDALYSTRLSPTIQASISAISIQHD--VGKTWSAEDEGRVSLGAELYFSAKERSAGVSTGLRF-TTTALFNPMLGHMSGAYTARVSRDLALSSRFDFNVYSFESEWTMGVEGV-VKARASTNV-SLMWEGRLRNMLVSL--GVKALGLEVAF Ganpr1 YYLEAGWNEDAYFSNLNASSRAILDFPTPGLSLHLGKFRAAYTLGL-KSGGFLYTNRRLA-GTTLLYGRI-H-QLEAVHSHRLSPNLLLVNTALTLAYK--SSSTYDSDASSQLDAGGELYYVADERSGGVACGLRV-RQTLTLNPMMGHLSFSYTSTVAHGADVSARYDFNAYSYESDLAVGVEE---MVKFGVGI-RLTFQKALPRAIVSF--GVRDVGVEVQI Gloin1 YFKTIGWNDDNQYSNLCSASRAILDFQTPGLTFAISKLKASYSMNLNGSLGYLFTSRPLE-MIDLLYGRLFV-PLEAIYSRKFSQWMQCVVTAVSLQYD--VGQSYTTDGEGEWSIGAELYYGIRERSGGVSAGIRY-RTTYLINPIMGHMSAAFAAQVSDDLALCPRFDFNMYSYESDLIIGAEGI-VKATVGTSV-TLLWEGRYGKTLFSL--GLRSIGLQFQY Hisca1 FSDASKWNRDNSYSQLTMTANALLDFSTPRLKVNLSSFATTYTLGIDGSISYLFTTVPLK-LVPLLHATLHLPPLTGLFLRRLSPTTQLSLAFCSILHD--TGKLFSTDNASLLSAGAEAYYSPVSSVVGLSTGLRF-TTTLTLTPLTGSMSTTYSLLASPNVSFSSRFGFNVYSWESEMVAGCESV-IKVRVDQSI-RALWEGRVKELLVSA--GVKSVGVSVLY Klula1 FEECTSWNKDNSYENIVGTSRNILQFDIPALKVQVSNSYNTLELTINGSLTYLYTNCENQ-MTQLAYGRMFY-PLEAMYIRRFPNYYQFILKCSSLQKN--TGIIFSTNEASSLSIGSEIWCALLNLSPGCSTTLRY-CSTLSLNPLYGHVSSTYSIKTHENLTFCTKYDFNIYSIQSNLTLGMEQV-FKVSTSLRL-RLLWEGKIRGFLISA--GASKFGIQLQY Lacbi2 YYKATGWNEDNLYANLTRSSNAILDFTVPGLHLTVSKFKTTYSMTLHGSVGYIFTSCDLN-MIELLYGRFYL-PLDALYSTRLSPTVQALVAAISLQHD--VGKTWSAEDGGRVSMGAELYFSAKERSAGVSTGIRF-TTTALFNPMLGHMSGAYTARVSRDLALSSRFDFNVYSYESEWTMGAEGV-VKARASTNV-SLMWEGRLRNMLVSL--GVKAIGLEVSY Lenti61 YYKQTGWNEDNLYANLTRSSNALLDFSVPGLHFSISKFKTTYSMNLNGSVGYIFTSCDLD-MVDLLYGRIYI-PLDALYSTRLTPTLQGMVAAISLQHD--TGKTWSAEDGGRVSVGGEFYFSAKEKSAGVSTGIRF-TTTALFNPMLGHISGAYAARVSRDLSLASRFDFNVYSYESEWSMGAEGV-VKAKVSTSI-SLLWEGRLRNVLVSL--GVKSIGLELSY Malgl1 YWRATGWNDQSSYLNLSKASDVLLDFTTPGVIFSSATFTASTRILLSGFIAYSHASTNS--CIQLLYGSMHA-PVEALCVFRLSEHWQIMATALSLQHQ--SSRTYSLDDAATLSAGGELFFSIAEKSGG----------LLTFH--------------------------------------------------------------------------------- Mellp23 HYAATGWEQDNEYSQLTQPTRALLDLNFVGLNFSLGKFANSASLSLTGSISYICSGLQST-FVELMYGRLHL-PLDGLYTKRISPSLQALITLVSINHH--TKKSYSTDDGGRFSAGAEIYFSPKGKSAGVSTGVRF-CTTATLNPIMGQISSSYGTKVGRNVALATRFDFNVFSFESDITFGGESM-LKARFSPVF-TVMWEGKWQECLIGL--GLKGVFLELQY Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 YYRASGWNEDNQYSHLCATSRALLDFQAPGLSLRLSKFKTTTTMNLEGSVGYLFTSRALH-LVDLLCGRMNL-ALEMLYSRRISKHRQYVLSGISFQYD--KGKSFTTDDGGYWSAGAEVYYSATEKLGGLSTGLRY-RTTQTLNPIMGHVSSSYAAQVHPDLGLCSRFDFNLYSYDSELTAGVEGV-IKARLGVQL-AIMWEGRFNKLLFSL--GFKSVGLEIQY Mucci2 FYRSSGWNEENQYSNLCSWSRAILDFHTPGLSLVISKFKPSYTLNLNGSLGYLYTSRALD-MIDLLYGRMFF-PLEAMYVRRISEHVQYSVTAVNLQYD--VGKSYTSDDGGQWSAGTELYYGVLDKSGGLSTGIRY-RTTYTLNPIVGHMSTSYVAKVSDQLVMCSRFDFSIYSYESDLALGFEGL-IKARWGFAL-ALMWEGRFKNTLFSL--GLRTIGLEVQY Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 FYGATGWNEDNKYNELNATSRELIDFPLPGLRLTLSSFATSYQLGVDGSISYLHSSIPLA-LLRLLYGRLYL-PLEGMIIKRFTQALQVQVRAVSVQYD--KGKLYSTDGGGRFSVGGELYYGTLNKSGGMSLGARF-ATTLTINPLMGNINATYALLAREYCSLATRVDFNVYSYESEWAVGMEGV-LKARLDNNM-GLLWEGRAKSLIFSI--GTRSLGLEVQY Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 FAEATHWNRDNSYSSLNTTAQSILDFSTPRLRVHLSSFATSYTLGLDGSVSYLFSTVPFK-ISPLLHASLHLPPLYALFLRRISSNMQLSLAVCSLSHD--TGKLFSTDNASLLSAGAEAYYSPISSLIGMSTGLRF-TTTLTLAPIVGSLSTTYSLRASPNLAFSSRFGFNVYSWESEMVAGCESV-IKLRIDQSV-RLLWEGRVKELLVSA--GVRGVGVSVLY Phybl2 YYRSSGWNEENQYSNLCSWSRALLDFYTPGLSLHLSKFKPSYTMNLNGNIGYLYTSRPLD-LVDLVYGRMFF-PLEAMAVRRLTQNLQYLITAVNLQYD--VGRSYTTDDGGQWSIGTEIYYGTLDKSGGLSTGLRY-RTTYTLNPIVGHMSTAYVAQVSEELALCSRFDFSIYSYESDLALGFEGL-MKARLGFSL-ALMWEGRFKNTLFSV--GLRTIGIEVQY Picst3 FYKSTNWNEDNIFSNITASSLAILDFPIPGFKLDSSNLASSFTLSINGSLAYLYSSVPLD-ALVLLYGRMYF-PLEAMIIKRISAHTQLLIKCINLQKN--APKIYSTNESSVISIGTELWYAARTMSPGLSTAFRY-STTLAVNPILGHLSSTYTVKTSVASTFSSRYDFNFFSYASNLSLGFESV-VKFSTSLNV-KILWEGRVKDFLVST--GVNRFGVSFSY Plicr1 YYQATGWNEDNLYANLTRSSNAILDFAVPGLHLSISKFRTSYSMNLNGSVGYIFTSCELD-MVELLYGRFYL-PLDALYSTRLSPTLQGLVAAISLQHD--VGRTYSAEDSGRFSAGAELYFSAKEKSAGVSTGIRF-TTTALFNPMMGHISGAYAARVSRDLSLASRFDFNVYSYESEWTMGAEGV-VKARASTSV-SLMWEGRLRNMLVSL--GVKAVGLELSY Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 HYAAIGWDPDNDYAQLTKPTRALLDLNFLGIHFSLGKFANSASLSLTGSVSYVASSIQST-VVDLLYGRFHI-PLDALYSYQFSPTLQALATLVSMNHD--TGKSYSTEDGGRFSVGGELYFSAQRKSAGVSTGIRF-CTNATLNPIMGQISTSYGTKIGPNLAMATRFDFNFFSFDSDITFGLESI-LRARVSPVL-TLMWEGRWKECLIGI--GIKGICLELQY Punst1 YYRATGWNEDNLYSNLTRSSNAILDFNVPGLHFSVSKFKTSYSMNLNGSVGYIFTSCDLD-MVDLLYGRFYL-PLDALYSTRISPTLQALVAAISLQHD--VGKSWSAEDSGRFSAGAELYFSAKEKSAGVSTGIRF-TTTALFNPMLGHMSGAYAARVSRDLSLCSRFDFNVYSYESEWTIGSEGV-VKARASTTV-SLMWEGRIQNLLVSL--GVKSIGLELSY Rhior3 --------------------------------------------------------------------------MEAMYVRRLSRHVQYLVTAVNLQYD--IGKSFTSDDGGQWSVGTEVYYGILDKSGG------------------------------------------------------------------------------------------------ Rhoto1 FLLATNWNTDNHYASLTHPSRQLLDFSIPGLHFAVASFTPGVNLSLAGQLSYLFSSAPID-VVQLLYGRLYV-PLDALYVHRLSPTLQALVSLITLQQD--TGRSYAVGDGGRWSAGGEIYFSAQERSAGVSTGVRF-TTSATINPIMGQLSTAYAVRVGRDASLASRFDFNLYSYDADLTVGGEGV-LKVRASTNV-AMLWEGRLGDFIVSA--GLRSIGLSASY Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 FYQSTHWSTQNSYEDITATSRTLLDFRIPAIHLQISNTFNSLDFSINGSLSYLYSDAQQD-ATELYYGRMYY-PLEAMIIKRLSPQTQFMLKGVSFQRD--SHRIFSTSDLSSLSLGAEFWLGLVSLSPGCSTTLRY-YTTLSWQPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCESV-WKLSTSLRL-KLLWEGKWRGFLISA--GTAKFGIQFQY Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 YYAATGWNGENGYGYLTRPIDALLDFPVPGLHLAVANFATAAALHLAADVAYAASSAPIQ-ASSLLYGRLYA-PLDALAALRMSPTMHGLAAAISVHHD--TGPSYSADDGGRFSVGAELYVSAREKSAGLSTGVRF-TTTALFNPMLGHLSASYAARVGRDVALASRFGFNMYSYESEWTMGVEGV-VKARASTNL-ALLWEGRVRNMLVAL--GVRAIGLELAY Schpo1 YLKKTNWNIHNLYCNLTQTADNILNFEIPGVSCQLSSFASGCKISLNGSMSYVYTNVNLH-FYELLYGRMHL-PLDAIFATRLSPWLLFFIQGVNWQYD--TGKVYESSGAMRWSLGFETYYGVLTKCAGASLGMRL-HSTCTLNPIVGHITSTFSTAEPRTKAFSAQYDFNIYSYESQLKLGIESL-LKGTCSTSV-SISWQARIRNFLLTI--GTLFFGVHFEY Sorma FYGATGWNEDNKYNELNATSRDLIDFPLPGLRLTLSSFATSYQLGVDGSISYLHSSIPLA-LLRLLYGRLYL-PLEGMVIKRFTQALQVQVRAVSVQYD--KGKLYSTDGGGRFSVGGELYYGTLNKSGGMSLGARF-ATTLTINPLMGNINATYALLAREYCSLATRVEFNVYSYESEWAVGMEGV-LKARLDNNI-GLLWEGRAKSLIFSL--GTRSLGLEVQY Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 YYYSINWREDQYST-LLTDSRRLLDFAVPGFSITLGKLKGTYTLGI-RSVGFLFTSAPLS-CVDLVYGRL-F-ELEALYSKSLSRNTLIVASGVNLLYS--SLSSYSSDDHSNWSAGSEVYYTAKERSGGLSLGARY-KNTFLANPMMGHVSASYATTIRKNLTMATRYDFNVYSYEADLVLGVEQL-VKARVSLSL-ALKLEGQYKRALFSI--GLRSIGIELQI Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 YYKATGWNEDNLYANITRSSNAILDFTVPGLHFSISKFKTTYSMNLNGSVGYIFTTCDLD-LIDLLYGRLYI-PLDALYSTRISATLQGLVAAISLQHD--TGRTYSAEDSGRISAGAEVYFSAKEKSAGVSTGIRF-TTTALFNPMMGHISGAYAARVSRDLSLCSRFDFNVYSYESEWTVGTEGV-VKARASTSV-ALMWEGRLQNILISL--GVKSLGLEVSY Tapde11 ------WNQENFYSDLLHTSRNLLDFKVPGLQMNFTAFANSHRLTIGGSLSFLHSSRPFD-VIDLLYGRLHL-PLEAIFARRLSPTRQLILTALSLQQD--YGTIYNTDDAGRFSAGMEIYYGALHKSGGISLGMRF-ATTLTVNPLVGHLSSTYTMKIAGLATLCSRLDFNIFSYESDLTLGGEGV-VKAYVHSAMGGLLWEGRVKDFLVSI--GGGAFGVEMQY Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 YYQAIGWNQDNTYSNLTRSSADKRDFQIPSLVLQLANFFTSYSLDLNGAISYITTSEAID-VVELLYSRLHL-PLSGLAVTRLTPTLQAHLAFLSLQHD--TGRTYSAQDGGRFSAGGEVYFSAKQRSFGISTGVRF-TTTLLYNPLIGFISSAYSAQISPTVAVSSRFGVNVYSYESDLSIGGEGV-LRARISGTL-AVLYEARIKNCLVSI--GARSLGLEVQY Trire2 FYEATGWRRDNSYAALNSTTDALLNFRTPGLRLTLSAFATSYQLGVDGSISYLFSSVPLD-LLRLLYGRLYL-PLEALLVRRLSPALQAQFSAVSLQYD--VGRLASTDGGGRFSTGGEIYYGTLNKSGGISIGARF-ATTLTLNPLMGNIAASYAVMAGKDCSLATRMEFNIFSYESSWAVGMEGV-VKARLDQNL-GVLWEGRVKSLLFSL--GSRTLGLEVQF Umbra1 YYRASGWNEENQYSNLCAWSRSMLDFTVPGISLVMSKFKPSYTIDLNGSMGYLYTSRPLE-TLNLVYGRMFL-PLEAVYSRRLSETTQYIITAFNLQRD--VGRSYTTDDGGQWSAGAELYYGILDKSGGFSTGLRY-QTTYTLNPIVGHMSTAYVAQVSDELVLCSRFEFSIYSYESDLAVGFEGL-VKARFGLAV-ALMWEGRFKNLLFSL--GIRSVGLELQY Ustma22 YFHATNWNEYNSYLHLTSCSSAILDFCVPGLSLSISAFFTTYRLGLRAGIGYIYASTDSE-IIELVYGCMHV-PLDALWTKRISPTWQLIVTAVSLQRD--TGRSYSIDDAGRFSAGAEVFISTVEKSAGLSTGIRF-STTATLNPMMGHLSTAYAARMARDVVVCSRFDFNVYSYESEWTMGAEGV-LKARISSTI-RLLWQGRLSHCLVSL--GVKSIGLEVMY Walse1 YFRATEWNPDAQYSNLNRASAAILDFYPPALSVSLSSFASSCSLSLSGSLAYLASSIDLS-LVHLLYGQLHL-PLHSLYTRRLSPQSQLLISSISYQKD--QGNSYSVADGGHFSLGGEIYASAQEKSAGVSTGLRF-QTVALLSPITGYLSGTYSATIAKGLSVASRFEFNLYSYESVTTLGAEGY-LKARMTTEI-TLQYAGRLKSMLVSL--GLQSIGLELQY Zygro1 FEKSTDWNYDNSYANILASSRNILDFPVPQFKFQLSNTFNTMEVFFNGSMTYLYTDAEND-VTDLYYGKMSY-PLEAMLIKRLNESTQLTLQCVSWQHD--TGRIMSTNDLFSLSLGGEVWLGIVTLSPGCSTTLRY-CTTLTWNPLFGHISSTYTAKTSSSSTFSTKYDFNLYSIESNLSFGCESV-WKLSTSSKL-RLLWEGKFKGFLLSA--GTNKFGIQLQY [Cluster3104.fasta_al_trimmed; alignment length = 124] Allma1 VCVFCGSSEAAKLLGEYLAANSIQLVYGGGSAGIMGTVAKAVNGGKVLGIIPRALLIEVDDMHTRKQLMNEDAFITLPGGLGTLEEFFETATWSQLNIHAKPILVLDTGYYAPIFMAAASSGFV Ashgo11 VCVYCGSSDAARSLGELFHQLQWKLVYGGGTTGLMGTVARATCDGYVHGIIPNALVTIVPDMHTRKAMMARDAFVALPGGYGTLEEVMECITWSQLGIHQKPIILFNIGFYDSLVDRAIADGFI Aspfu1 ----CGSVETARALAHEFHKNNVQLVYGGGTKGLMGELARTLGPQAVHGVIPRALVTIVPDMHTRKRLMAESGFVSLAGGFGTIEEVMEMTTWNQLGIHHLGIVLLNVGYWDGLVQSAVKEGYI Aurde31 VAAYCASSNAAASIGKAIAS--RGLVYGGGSSGLMGVVSLATAGGKVVGVVPAAMLVIVNSMHERKVTMAEGGFIGLPGGFGTFEEVFEVITWSQLAIHNKPVVLINVGYWDPVVKQGIASGFI Batde5 ---------------------------------------------------------------------------------------------------------------------------- Botbo1 VCVFCGASAAARSLAHAFHKHGITMVYGGGANGLMGEISRTLGPDAVHGVMVDALVAVVPDMHTRKQRMASSGFVALPGGYGTMEEFMEVVTWNQLGIHARGLVVYNVGFFDGLVRRAVDAGFV Botci1 ICVFCGSSAMARSLAQHMASQNISLVYGGGTVGLMGEVARTLGPTAVHGIIPAPLVTVVKDMHARKSMMAKSGFVALPGGYGTLEELMEVVTWNQLGIHTRGIVVLNVGYWDGLVKNSVEAGFV Caeel ---------------------------------------------------------------------------------------------------------------------------- Canalb1 VCVFCGSSEEASKFGKALADKKWGLVYGGGSTGLMGAVASGCNGGYVHGIIPEALITLVKDMHTRKRLMAQDAFVALPGGIGSIDELAEITTWCQLNIHGKPIVVYNVGYYDNFIQGFVDCGFL Cangl VCVYCGSAAAAEELGALIHARRWSLVYGGGTTGLMGGVARGAKDGSVHGIIPDALVTVVPDMHTRKRLMASDAFVALPGGFGTLEELLECVTWSQLGIHNKPVVVLNTGYFDALFRDAIAAGFI Capow ICVYCGASVAARELGRLIAKSGHTLVYGGGSYGTMGALADGTAGGQVLGIMPRFMERLVTSLHERKFQMLQDGVVALPGGAGTFEELMEALSWKKLGIIDSPIVLFNLGFYDPLLDRAAQENFL Catan2 LCVFCGSSAAAEEIGRTLAQHNVRLVYGGGNGGLMGAVARSCAGGKVLGIIPTALAIMVEDMHVRKQLMNQDAFLTLPGGIGTVEELMETATWAQLHIHSKPVIVLNQEFYTPLIENAVNSKFL Cioin ---------------------------------------------------------------------------------------------------------------------------- CocheC53 VCVFCGASEAARALATALHKANTKLVYGGGTVGLMGEVARTLGPDSVHGIIPAALTTVVKDMHTRKQMMAQGGFVALSGGYGTFEELMEITTWNQLGIHSMPVIVFNVGYWTGLVKNAVKSGFI Coere1 ACVFCASSEAARELGSELVKGGYGLVYGGGTWGLMGHLARSVAKGKVLGVMPRALTVLVDNMHERKSKMEKSAFIALPGGFGTFEELLEIITWSTLSIHRKPIIVLDTGYYSALITKAVDAGFI Conco1 ICVFCGSSQVAREVGTYLAKHNYGLVYGGGRNGIMGTVAKSVNGGSVISIILKLCAIEVPDMHTRKALMHSVAFLTLPGGYGTLEELLEMTTWGQLGIHSKPVMVLNIELYTPLIYSMVDNGFI Conpu1 VAVYCAASNAALSVGHALAEANRPLVYGGGNAGIMGVVSGAAENARVIGIIPNAILIVVSSMHERKVEMATGGFIGLPGGFGTFDEVLEVITWNQLNIHNKPVVLLNVGYWSPLVRTGIEEGFI Copci IAVYCASSSAAISVGKALASANRPLVYGGGSKGIMGIVSGACSGGKVTGIVPYAMVIVVDSMHERKVQMSVDGFIALPGGFGTFEELLEVTTWTQIGIHKKPVVLVNVGFWNPLIRSSIGHGFI Croqu1 ---------------------------------------------------------------------------------------------------------------------------- CryneH991 VCVFCGSSKASESVGKALAKANIPLVYGGGRRGIMGVVSQSTANGYVHGIVPRALVEVVGSMHERKLAMAKGGFIVLPGGYGTLEEALEMITWNQLGIHRLPIIILNINFFTHLFENSVEAGFI Crypa2 ICVYCGSSAAAAQLAVVMAANDIGLVYGGGTVGLMGEIARTLGPDAVHGIIPAPLVTVVPDMHTRKKMMAQSGFIALPGGFGTMEELLEICTWNQLGIQRSGICVLNVGFYDGLIGKSIDEGFI Debha1 VCVFCGSSEDAAKLGKVLADKNWGLVYGGGSTGLMGAVAEGCNGGYVHGVIPEALITLVKDMHTRKRLMGKDAFVALPGGYGTLEELMEMVTWFQLNIHNKPIVVYNMGFYDNFIQDSIDSQFV Dekbr2 VCVFCGSSKEASELGSLLAEENNGLVYGGGTTGLMGCVAKAVAGQYVHGIIPEALVTVVTDMHTRKELMAQDCFVALPGGFGTLEELMEITTWSQLGIHAKPIVLLNIHFYDEFVRGCIKRGFI Dicdi ICVFCGSRQVTEVLAKEMAKRNYGLIYGGGNIGIMGAVSQGVAGGRVKGIIPRSLSVFVDDMHTRKEIMYNEAFIALPGGMGTFEELFECITWNQLGIHSKPVGILNIGYYDPLLKTSVGSGFV Dmel ---------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------- Falba VCVFLASALLAREAGERLAKNNVDIVYGGSRLGCMGALAGGCAGGRVIGVIPKFFEHIVTSMHERKQMMTNDAFLVLPGGLGTLDELFETITWRALGVHAKPIVILNYGFYDHIVKAASERGMI Fomme1 VAIYCGSSNAAVSVGAALARNGRPLVYGGGSKGIMGVVSGSAQGGDVTGVVPYAMYVLVNSMHERKVEMARSGFIGLPGGYGTYEEVFEAITWTQLGIHDKPVILLNVSFYSPLVRNGVNEGFI Fusgr1 ICVYCGSAEAARALGKAMAENNIDLVYGGGTVGLMGEVAKSLGPDSVHGIIPEALVTVVKDMHTRKKLMAESGFIGLSGGFGTMEEIFETTTWNQLGIHNRGIVLLNIGYWDGIMDRAAEQGFV Galma1 IAVYCGSSAAAHSLGVALSAADRSLVYGGGSKGIMGIVSGSVNGGKVVGVLPRAMVILVDSMHERKVEMAKDGFVGLPGGFGTFEEVLEVTTWSQLGIHDKPVILLNVSFWDPLIKNSIDAGFI Ganpr1 VTVFCGSSESAKRLGAILASRNIHLVYGGGAIGLMGEIAKSTNGGQVLGIIPEAMK-VVKSMHERKQLLNHSAFIAMPGGYGTFDELFEVITWAQLNIHRKPIALLNTGYFDHLVDNSVTEGFV Gloin1 ---------------------------------------------------------------------------------------------------------------------------- Hisca1 ICVFCGAYAAARALAHIFHKENITLVYGGGTGGIMGELARTLGPKAVHGVIPTALVTLVPDMHTRKRTMAQSGFVVLAGGFGTLEEAMEMVTWNQLGIHNCGIVLLNIGYWDGLVEKSVESGFV Klula1 ---------------------------------------------------------------------------------------------------------------------------- Lacbi2 VAVYCASLNAAVSLGRALADSNRPLVYGGGTKGIMGVVSGTVGGGKVTGVIPYAIFIIVESMHERKVEMAKGGFIGLPGGFGTFEEVLEVTTWTQLGIHTKPVILLNVSFWEPLVRNGIEEGYI Lenti61 VAVFCGSSHAANSLGKAMAEAGRPLVYGGGSAGIMGAVSGAVAGGDVTGVVPYAMVIVVNSMHERKAEMARCGFVGLPGGYGTFEEVLEVVCWSQVGIHSKPVLVVNVNFWNPLVRNGIENGFI Malgl1 ---------------------------------------------------------------------------------------------------------------------------- Mellp23 ---------------------------------------------------------------------------------------------------------------------------- Mnele ---------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------- Morel2 ITVFCGASEMAKDLGREMLKRNYGLVYGGGSYGLMGAIAQTIGGGKVIGVIPEALKIVVKDMHTRKALMNKDGFITMPGGYGTMEELLEITTWSQLSIHTKPVMLFNMGYFEYLIEHSIEEKFV Mucci2 VCVFCGSGQEAYELGKVLAENNVRLVYGGGSVGLMGAVAKGTNGGKAIGIVPEPLYVIVPDMHARKKRMEEDAFVCLPGGFGSFEEVLEIITWSQLNVHSKPIVLLNTGFYKLFINFSAQEKFI Mydma ---------------------------------------------------------------------------------------------------------------------------- Neucr2 ICVYCGASEAARQLARSMAANNIDLVYGGGTVGLMGEIAKTLGPDSVHGIIPEALVTIVKDMHTRKMMMAQSGFIALSGGYGTMEELFETVTWNQLGIHDKGIVLLNIGFYDGIIQNSIQEGFV Orpsp11 ICVYCSSSKLALETGEAIAKEGYNLVYGGSTRGCMGKVAEGVNGGSVTGIIPEGIVVVTKDMNDRKQLMEEDIFLALPGSFGTLDEIIQVIVTKQLSYHNKAVIFLNLDYYKPLFENFYKFGFA Pench1 VCVFCGSVQAARALAEEFHKHNVQLVYGGGTTGLMGEVARALGPKAVHGIIPRALVTIVADMHTRKRLMAESGFVSLAGGFGTIEEVMEMTTWNQLGIHKVGVVLLNIGYWDGLVRNAVKEGYI Phybl2 ---------------------------------------------------------------------------------------------------------------------------- Picst3 VCVFCGSSEMATELGKAFASRNWGLVYGGGSTGIMGAVARACSGGYVHGIIPEALITLVKDMHTRKRLMGEDAFIALPGGYGTLEELMEVVTWFQLNIHNKPIVVFNMGFYDNFIEDSIDNEFV Plicr1 IAVYCASSNAAISVGNALVAAKRPLVYGGGSKGIMGVVSGTVYGGKVIGIIPHAMVIIVDSMHERKVEMAKGGFIGLPGGFGTFEEVLEVSTWTQVGIHNKPVVVLNVSFWEPLIRSGIDAGFI Polpo ICVFCGSREVTKKLGEEMNRRKYGLVYGGGNVGLMGTISETIGGGRVQGIIPHGLAVYVEDMHSRKKIMYEDAFIALPGGIGTFEELFETLTWIQLGIHSKPVGILNIGYYTHLLETSAKRGFI Pucgr2 ---------------------------------------------------------------------------------------------------------------------------- Punst1 IAVYCGASLAAVSLGRALAKAGRGLVYGGGNGGIMGIVSSTVEGGDVLGVIPYAMVIAVRSMHERKTIMADCGFIGLPGGYGTYEEVLEVTTWTQLGIHNKPVVVVNVGFYDPLIRNGVRNGFI Rhior3 ACVFCASSEEA---------------TSGGSVGLMGATAKAVNGGQALSVVPEPLFIIVPDMHSRKKRMADDAFIVLPGGFGTMEEMLEMITWSQLNIHSKPIILLNTNFFDLYIQLAAKEQFI Rhoto1 ITVFCGSSEATDQLARALARRGVTLIFGGGTKGLMGRVSSKAEGGKVHGIIPAAFLTVVGSMHERKKLMADYAFIGLPGGYGTLEEVAEMTTWSQIGVHLKPVVLLNIGFYSSLIDHAISSGFI Rozal11 ---------------------------------------------------------------------------------------------------------------------------- Sacce1 VCVYCGSSESAEELGALFHKLGWKLVYGGGTTGLMGKIARSTLSGQVHGIIPNALVTIVPDMHTRKRMMANDAFVAMPGGYGTFEEIMECITWSQLGIHNKPIILFNIGFYDKLLKHSIQERFI Salro ---------------------------------------------------------------------------------------------------------------------------- Schco3 VAVYCASSKAADSLGTAIAKAGRPLVYGGGSKGLMGTVSGAVGKGKVTGVVPYAMVIVVNSMHDRKVEMAREVFFGLPGGFGTFEEVMEVSTWTQLGIHRKPVILLNVGYYDPLIKNGISAGFI Schpo1 ---------------------------------------------------------------------------------------------------------------------------- Sorma ICVYCGASEAARQLARVMAANNIGLVYGGGTVGLMGEIAKTLGPDSVHGIIPEALVTIVKDMHTRKLMMAQSGFIAMSGGYGTMEELFETVTWNQLGIHDKGIVLLNIGFYDGIIQNSIEEGFV Sphar ---------------------------------------------------------------------------------------------------------------------------- Spipu1 ICVYCGSSEAAQELGEALVKNGIALVYGGGDKGLMGIIARTVGGGNVVGIIPEAMTTIVPDMHTRKKKMEENAFIALPGGFGTFEELFEAITWAQLNIHSKPIGVLNTGFYDPLIDKSIESGFI Sporo1 ITVFCGSSDTATSLARAIAQSQKTLVYGGGTKGLMGQVSKATAGGKVHGIIPSAFLTVCGSMHERKKMFADHAFVGLPGGYGTLEEVMEMTTWSQIGVHKKPVVLLNVGFYSHLIEGAISSGFI Stehi1 VAVYCASSNAATSLGHALGSSSRPLVYGGGSKGIMGVVSGAVKGGQVLGVVPAAMVIVVQSMHERKVEMAKVGFMGLPGGFGTFEEIMEVITWTQLGIHNKPVILINVNFYEPLIRRAVSEGFI Tapde11 ICVFCGSALAAEELANEMAKRNWDLVYGGGSTGIMGVMASSVAGQSVTGIIPRALTILVDDMHTRKRMMAESAFVSLPGGLGTLEEMFEVATWNQLGIHRDPVVLFNVGFYDHLIKHAVQEGFI Thetr ICVYCGSSAAAAELGRVLAGRNIGLVYGGGSVGLMGELAKTIEGGKVVGVIPRALAIVVDTMHERKTTMAADGFIALPGGFGTLEELLEISTWVQLGIQKKPIGVLNIGYYDPLIDRAITHGFI Treme1 VCVFCGSNEAAHAVGKALAEAHTPMIYGGGQRGIMGVVSKACAGGYVHGVLPRALVQVTGTMHDRKMRMAQGGFIVLPGGYGTFEEALEMITWNQLGIHRLPVIILNVNFYTPLFGSAAKAGFI Trire2 ICVYCGSAEVARELARVMAENDIDLVYGGGTVGLMGEVAKTLGPDAVHGIIPEALVTVVKDMHTRKKLMAESGFIALSGGYGTVEELFETVTWNQLGIHKRGICLLNIGYWDGIVDKAVEQGFV Umbra1 ICVFCGANEQANALGNLMVKKGYSLIY-GGQVGLMGAVAKAVGGGKAKGIVPVPLYVIVPDMHTRKQMMSEDAFIALPGGFGTMEELLEVITWSQLNIHSKPIILLNTNYYDLFINHCAGEKFI Ustma22 ---------------------------------------------------------------------------------------------------------------------------- Walse1 VCIYSGSSEVAESIGVALSSRDITVVYGGGDFGLMGVVARSANNGKVTGIIPRAMVVVVESMHERKLAMAE-AFIALPGGFGTLEELLEVTTWSQLNIHSKPVVAINVGFYEPLITTAVEAGFI Zygro1 VCVYCGSSGHAEALGKLFHQLGWKLVYGGGTTGLMGQIASATLDGKVLGVIPDALVIVVPDMHTRKRMMARNAFVAMPGGYGTLEEVMECITWSQLGIHAYPVVLYNIGFFDLLIEHSIEEGFI [Cluster3123.fasta_al_trimmed; alignment length = 281] Allma1 WTRDEIQAIYDSPVMDLLYYGSTVHRDPRAVQQCTLLSIKTGGCSEDCSYCPQSSKHVKASKMDEVLAAAKRAKEAGSTRFCMGAAWRTAAGRKTDFKKVLNHITEIR-GMGMEVCCTLGMLQAQQLKEAGLSAYNHNLDTSREYYGN-IITTRTYDDRLDTIGKVRDAGIKVCSGGIIGLGEDRVGMLHTLATLPEHPESVPVNALVAVPGTPLLIRMIATARIVMPRAMVRLSAGRMPEQALCFMAGANSIFTGDKLLTTGNNDWTADQQMFGLIGLKP Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 WSREEVQQIYETPLSQLTYAAATVHRDPAAIQMCTLMNIKTGGCSEDCSYCAQSSRYLKATKMDEVLKAARIAKDNGSTRFCMGAAWRDMRGRKTSLKNIKEMVSGVR-AMGMEVCVTLGMIQAKELKDAGLTAYNHNLDTSREFYPS-IITTRSYDERLRTLSHVRDAGINVCSGGILGLGEDRIGLIHTVANLPSHPESFPVNALVPIKGTPLLLRTIATARIVLPATIVRLAAGREEQQVACFMAGANAVFTGEKMLTTDCNGWDEDREMFGFYPMRS Aurde31 WSRAAVRDIYNSPLMELVFRAGIVHRDPTKIQLCTLMNIKTGGCSEDCSYCSQSSRYTTASRLEPVIEAARKAKENGSTRFCMGAAWRDMNGRKRSFERILEMVRQVR-AMDMEVCTTLGMLQAKALKEAGCTAINHNLDTSREFYPQ-VITTRTYDDRLQTIANVRDAGIHVCSGGILGLGEDRIGLIWECGNFEQHPESFPVNALVPIPGTPMLLRTIATARIVMPSTIIRLAAGREIQQAMCFLAGANAVFTGEQMLTTPCSPWDEDKAMMGLTGMRS Batde5 WTKQEIQAIYDTPLIELLYQAATVHRNPREVQQCTLLSIKTGGCTEDCAYCPQSSKHVKASKLDEVLEAARKAKDAGSTRFCMGAAWRDVQGRKTNFSQITEYVRQIR-GMGMEVCCSLGMLQAIALKEAGLTAYNHNLDTSREFYPN-IITTRSYDERLNTISNVRDAGISVCSGGIIGLGEDRVGMLHTLSTLPKHPESVPINALLAVPGTPLMVRMISTARIIMPKAMVRLSAGRQSEQALCFIAGANSIFTGDKLLTTPNNKASQDKEMIGILPKPA Botbo1 WTKSEIGEIYHSPLLDLVFRSASVHRDPSKIQLCTLMNIKSGGCTEDCSYCSQSSKYTEASRLEPVLEAARQAKANGSTRFCMGAAWRDLSGRKSGFERILKMVTEIR-GMGMEVCTTLGMLQARRLKEAGLTAYNHNLDTSRDFYPQ-VITTRSYDERLDTISAVRDAGISVCSGGILGLGEDRIGLIWEVANMPEHPESFPVNALVPIPGTPLILRTISTARIVLPTSIIRLAAGRESEQAMCFMAGANAIFTGERMLTTPCSGWDEDKSLLGLRGMES Botci1 --------------------------------------------------------------MESVLAAARIAKDNGSTRFCMGAAWRDMRGRKTNLKNVKTMVSEIR-GMGMEVCVTLGMIQAQELKEAGLTAYNHNVDTSRDFYPK-VITTRSYDERLNTIKNVRDAGINVCTGGILGLGEDHIGLLETVATLPSHPESFPVNMLVAIKGTPLMLRMVATARIVMPKTIVRLAAGREEQQVLCFMAGANAVFTGEKMLTTPAVGWGVDSVVFGLRPMES Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 WTKDEISKIYNAPLMDLIFNAQLKHRKPAEVQLCTLVNIKQGGCTENCSYCSQSSKHVQAEKLDAVMDIARDAKARGGTRVCLGSAWRDMQGRKSALDKISKVVKQINDELKLETCVTLGMIQAEILKQNGLTAYNHNIDTSREHYPN-VVTTRTYDERLETIKNVQKAGIKACTGGILGLGEDHVSFLYTLSNMSPHPESLPINRLVPIQGTPIILRTIATARLIMPESIIRLAAGREHEQFLCFMSGVNAIFTGKRMLTTMCNGWDEDIAMLGLKPMES Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow WTRAEIQEIFDTPLLDLMYRAATVHRDPRQVQQCTLLSIKTGGCSEDCAYCPQSSKYVKAERLQSVVDAARKAKEAGSTRFCMGAAWRDVIHRKSNFAHVLEMVSEVR-SMGLEVCATLGMLQAVQLKNAGLTAYNHNLDTSREFYPK-IITTRTYDERLNTIANARDAGLSVCSGGIIGLGEDRVGLLHTLSTLPTHPESVPVNALVPVPGTPLMVRMIATARILMPGSMVRLSAGRPIEQALCFFAGANSIFTGDKLLTTANNAFNDDQTLFGLVGKEP Catan2 WTREEIAQIYNSPIMDLLFYGSYVHRDPLAVQQCTLLSIKTGGCSEDCSYCPQSSKYVKGSKMDVVLAAARKAKEAGSTRFCMGAAWRSTAGRKTNFKQILGYVTEIR-GMGMEVCCTLGMLQAKQLKEAGLSAYNHNLDTSREFYPK-IITTRSYDDRLQTLAHVRDAGIHVCSGGIIGLGEDRVGMLHTLSTLPKHPESVPVNALVAVEGTPLLVRMIATARIVMPASMVRLSAGRMADQALCFMAGANSIFTGDKLLTTQNNEWEGDQRMFGLVGLKP Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 WTKDEISEIYNTSLIDLTYASASVHRDPAAIQMCTLFNIKTGGCSEDCSYCAQSSRYLKATKLESVLEAARIAKENGSSRFCMGAAWRDMRGRKTNLKNIKKMIKGVR-GMGMEACVTLGMVQAKELKDAGLTAYNHNVDTSREHYPS-VITTRTYDERLNTIKNVQEAGIHVCTGGILGLGEDHVGLIHTVATLPAHPESFPVNALVPIKGTPLILRTIATARLVLPTTIIRLAAGREEKQILCFQAGANAVFTGEKMLTTACNGWEEDKAMFGLRPMKM Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 WSREEVQEIFDSPIMELLYHGSSVHRDPLKVQQCTLLSIKTGGCSEDCKYCPQSSRYVKAQKMGEIMDAARRAKDAGSTRFCMGAAWRDVKGRKSNFKKILTHIKDIK-GMGMEVCCTLGMLQARMLKEAGLTAYNHNLDTSREFYPK-IITTRTYDERLDTINNAQQAGISVCSGGIIGLGEDRVGLLTTLASLPIHPESVPVNALLAVEGTPLMIRMISTARIIMPRAMVRLSAGRQPEQALCFLAGANSIFTGDKLLTTPNNEYTADQDMFGLVPKEP Conpu1 WSRQEIQKIYDSPLLDLVFRAGSVHRDPSKIQLCTLMNIKTGGCSEDCSYCSQSSRYTKASRLAPVIEAARKAKENGSTRFCMGAAWRDLAGRKRGFERILEMVREIR-AMDMEVCTTLGMLQAKQLKEAGLTAYNHNLDTSREFYPE-VITTRSYDERLGTISAVREAGISVCSGGILGLGEDRVGLIWEVSNMPEHPESFPVNALIPIPGTPLLLRTIATARIVLPMTIIRLAAGRESEQVMCFLAGANAVFTGETMLTTPCSPWDEDKELMGLQGMRS Copci WRREEIQTIYDSPLMELVFRAASIHRDPSKIQLCTLMNIKTGGCTEDCSYCSQSSRYTKASRLEPVLEAARKAKENGSTRFCMGAAWRDLAGRKRGFERILQMVREVR-GMGMEVCTTLGMLQARQLKEAGLTAYNHNLDTSREFYPQ-VITTRSYDERLHTIAAVREAGISVCSGGILGLGEDRVGLIWEVSNMPEHPESFPVNALVPIEGTPLLLRTIATARIVMPKTIIRLAAGREAEQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLEGMVS Croqu1 WTREEVQEVYDTPLMELVFRSATVHRDPSKVQLCTLLNIKEGGCTEDCSYCAQSSRYLEASKLEPVLVEARKAKANGSTRFCMGAAWRDLHGRKNGFKRILEMVRAVR-AMDMEVCTTLGMLQAEQLKQAGLTAYNHNLDTSREFYPE-VITTRSYDDRLGTLANVRAAGLSVCSGGIIGLGEDRVALVHEMSQLPSPPESFPVNALVPIPGTPLILRIIATARIVLPTSIVRFAAGREAEQAMCYMAGANAIFTGERMLTTPTSGWDEDLSMLGMSGLGS CryneH991 WRRSEIQKIFDAPLMEVIYRAATVHRDASRIQLCTLMNIKTGGCTEDCKYCSQSSSYTKASRLEPVLEAARQAKANGSTRFCMGAAWRDLAGKKSGFEKILTMVKEVR-GMGMEVCTTLGMLQAIRLKEAGLSAYNHNLDTSREFYPE-VVTSRSYDDRLSTIAAVREAGISVCSGGILGLGEDRVGLIHEVSRMPQHPESFPVNTLVPIPGTPLVLRTIATARIVLPKTIIRLAAGRETEQAMAFMAGANAIFTGEKMLTTPCSGWDEDKAMLGLRGQRS Crypa2 WTRKEVAAIYYQPLLELAHQAGIVHRAPGEVQLCTLMNIKEGGCTEDCSYCAQSKRYLVAKRVESVLEAARKAKENGSTRFCMGAAWRDMKGRKNSLKNVTEMVKGVR-ALGMEACVTLGMIQAKQLKEAGLTAYNHNLDTSREFYPS-IISTRSFDERLQTLAHVRDAGINVCSGGILGLGEDRIGLLQTAATLPAHPESFPVNALVPIKGTPLMLRTIATARIVMPATIIRIAAGREERQVLCFMAGANAIFTGEKMLTTDCNGWDEDEIMFGLRPMKS Debha1 WTKDQIREIYNTPLMELVFQSQIQHRNPQEVQLCTLLSIKTGGCTEDCKYCAQSTRYTKAERMDEVMKAARTAKANGSTRFCMGAAWRDMTGRKSGLKRISQMVTQINQELGMETCVTLGMVQAADLADAGLTAYNHNIDTSREHYPK-VISTRSYDERLQTIRNVQDAGIKACTGGILGLGEDHIGFLYTLSTMEKHPESLPINRLVPIKGTPMILKTIATARLIMPESIIRLAAGREHEQFLCFMSGCNAIFTGEKMLTTMCNGWDEDIQMLGLRPMKS Dekbr2 WTQDQIGEIYNTPLHDLLFYSQLITRNPSEIQFCSLSSIKTGGCTEDCKYCAQSSRNVKAEKLDTVFSQAKKAKQKGATRFCMGSAWRGMHGRKSALKKISGMVKKINDELGMETCVTLGMSQAEVLKKAGLTAYNHNIDTSRNHYKN-IISSRTFDDRLATGKRVQDAGISLCQGGICGLGEDRISFLHTLCTLKEHPESVPINKLIPIKGTPLLLRTIASARLLMPASIVRLAAGRESEQLLIFMAGVNAIFTGEKMLTTMCNGWDEDINMLGFVPMKS Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 WTRQEIQEIYGTPLLDLVFRSASVHRDPKKVQLCTLMNIKTGGCTEDCKYCSQSSRYTKAEKLEPVLAAARQAKANGSTRFCMGAAWRDLAGRKSGFKRILEMVREVR-GMGMEVCTTLGMLQAMQLKEAGLTAYNHNLDTSREFYPS-VITTRTYDERLETIANVRDAGISVCSGGILGLGEDRVGLIWEVANMPEHPESFPVNALVPIPGTPMLIRTIATARIVLPSTIIRLAAGRESEQAMCFMSGANAVFTGERMLTTPCSPWDEDKAMMGLEGMGS Fusgr1 WTKDEIAAIYYQPVLELAYQASTVHRNPSEVQLCTLMNIKTGGCTEDCSYCAQSTRYVPAKRVESVLAAARIAKEKGSTRFCMGAAWRDMRGRKNSLKNIKAMVEGVK-GMGMEVCVTLGMIQAKELKAAGLTAYNHNVDTSREFYPN-VITTRSYDERLQTLSHVRDAGINVCSGGILGLGEDRVGLLHTVSTLPSHPESFPVNALVPIKGTPLMLRTIATARIIMPSTIIRIAAGREEKQALCFMAGANAIFTGEKMLTTECNGWDEDAAMFGLEPMKS Galma1 WKKDEIQQIYDTPLLDLVFRAASVHRDPTKIQLCTLMNIKTGGCSEDCSYCSQSSRYTKASRLEPVLEAARKAKENGSTRFCMGAAWRDLAGRKRGFERILEMVREVR-GMGMEVCTTLGMLQARQLKEAGLTAYNHNLDTSREFYPQ-VITTRSYDDRLETISAVRDAGISVCSGGILGLGEDRVGLIYEVANMPEHPESFPVNALVPIPGTPLLIRTIATARVAMPATIIRLAAGRETDQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLDGMRS Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 WTRKEIKSIYDSPMMDLLYFGAKVHRDPLAVQQCTLLSIKTGGCSEDCAYCPQSSKYVKATKLDEVLVAARKAKEAGSTRFCMGAAWRDLHGRKSNFNKIIGYVKEIR-SMGMEVCCTLGMLQAKALKEAGLTAYNHNLDTSREYYPK-IITTRSYDERLETISNVREAGISVCSGGIIGLGEDRVGMLHTLATMPQHPESVPINALVQVEGTPLMVRMISTARIVMPKSMVRLSAGRQPEQALCFFAGANSIFTGDKLLTTDNNDFNSDQEMFGLIPKPP Hisca1 WTRDEIRQIYETPLHQLTYAAATVHQDPSAIQLCTLMNIKVGGCSEDCSYCSQSSRYLQASKMEATLEAARIAKENGSTRFCMGAAWRDMRGRKNSLRNIKKMISGVR-AMDMEVCVTLGMIQAKELKDAGLTAYNHNVDTSREFYPS-VITTRTYDERLQTLSHVRDAGINVCSGGILGLGEDRVGLLHTAATLPAHPESFPVNALVPIKGTPLVLRTVATARIVLPKTTVRLSAGREEQQVACFMAGVNSVFTGEKMLTTDCNGWEEDKRMLGFYPMAG Klula1 WTKEQLAEIYHTPLMELMHQAQLQHRDPTKVQLCTLMNIKAGGCSEDCKYCAQSSRYLKAEKMEEVIKEAQIAKENGSTRFCLGAAWREMRGRKSALKRIGEMIGKIN-EMGMESCVTLGMVQAKQLKDAGLTAYNHNIDTSREHYPK-VISTRSYDDRLQTIKNVQDAGIKACTGGILGLGEDHIGFVHTLANMSPHPESLPINRLVSIKGTPMILRTVALARIVMPQAIIRLAAGRETEQFLCFMAGCNAIFVGKKMLTTMCTGWDEDKAMLGLQPMES Lacbi2 WTKQEIQQIYDTPLLELVYRAASVHRDPTKIQLCTLMNIKTGGCSEDCSYCSQSSRYTKASRLEPVLEAARKAKENGSTRFCMGAAWRDLAGRKRGFEKILEMVREVR-GMGMEVCTTLGMLQARQLKEAGLTAYNHNLDTSREFYPQ-VITTRSYDERLDTISAVRDAGISVCSGGILGLGEDRVGLIYEVSNMPEHPESFPVNALVPIPGTPLLIRTIATARIAMPATIIRLAAGRESEQALCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLSGMRS Lenti61 WTKQEIQKIYDSPLLDLVFRAASVHRDPSKIQLCTLMNIKTGGCSEDCSYCSQSSRYTKASRLEPVLEAARKAKENGSTRFCMGAAWRDLSGRKRGFERILTMVREIR-GMGMEVCTTLGMLQARQLKEAGLTAYNHNLDTSREFYPE-VISTRSYDDRLDTISAVRDAGISVCSGGILGLGEDRVGLIWEVANMPEHPESFPVNALVPIKGTPLILRTISTARIVLPGTIIRLAAGRETQQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLEGMGS Malgl1 WERSEVQALFDQPLLELVFQAASVHRDARKIQLCTLMNIKEGGCSEDCAYCSQSSRYSHASKLENVLEEARRAKANGSTRFCMGAAWREIGGRKRGFNRILDMVREIR-GMGMEVCTTLGMLQAQQLKEAGLSAYNHNLDTSREYYGK-VITSRTYDDRLQTIAHVRDAGISVCSGGILGLGEDRVGLIWEMSRLPEAPESFPVNALVAIPGTPMMLRTVATARIVLPTSIVRIAAGRESEQAMLFLAGANAIFTGHRMLTTPTSSWDQDRAMLGLSPMKS Mellp23 WSRQEIQEVYDTPLMELVFRAATVHRDPSKVQLCTLLNIKTGGCTEDCSYCAQSSRYLEASKLEPVLAEARKAKANGSTRFCMGAAWRDLHGRKNGFKRILEMVKEVR-AMDMEVCTTLGMLQAEQLKQAGLTAYNHNLDTSREFYPE-VITTRSYDERLATLENVRAAGLSVCSGGIIGLGEDRVGLVYEMSQLPSPPESFPVNALVPIPGTPLILRIIATARIVLPTSIVRFAAGREAEQAMCYMAGANAIFTGERMLTTPTSGWDEDLSMFGIRGLGS Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 WKKEEIDAIYHSPIMELLYHGANVHRDPLAVQQCTLLSIKTGGCSEDCKYCPQSSSYVKAQKMGEVLEAARAAKAAGSTRFCMGAAWRDLAGRKSNFKKIVGFVKEIR-AMDMEVCCTLGMLQAGQLKDAGLTAYNHNLDTSREYYPK-IITTRSYDERLETISKVREAGISVCSGGIIGLGEDRVGMLHTLSTMPAHPESVPVNALLAVEGTPLMVRMIATARIVMPKTMIRLSAGREPEQALCFMAGANSIFTGDKLLTTPNNKFNADQQMFGLVPKAA Mucci2 ----------------------------------------------------------------------------------MGAAWRDLAGRKSNFNKILDHVKVIR-SMGMEVCCTLGMLQAKALKNAGLTAYNHNLDTSREFYPK-IITTRTYDERLKTIDNAQNAGISVCSGGIIGLGEDRVGLLHTLSTLKQHPESVPVNALLAVEGTPLMIRMIATARIIMPKSMVRLSAGRVPEQAMCFMAGANSIFTGDKLLTTPNNEISDDKKMFGLVPKPP Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 WTKEEIREIYQTPLMELVYSASTLHRDPASVQLCTLMNIKTGGCSEDCSYCAQSSRYVKATKIDEVLQAAKIAKENGSTRFCMGAAWRDMRGRKTNLKNIKAMVSGVR-ELGMEACVTLGMIQAAELRDAGLTAYNHNVDTSREYYPN-VITTRTYDERLKTINNVRQAGIHVCSGGILGLGEDRVSFLYTVATMESHPESFPINALVPIKGTPLTVRMVATARLVLPGSVIRLAAGRESEQALCFMAGANAIFTGEKMLTTPCSGWDEDKAMFGLRPMLP Orpsp11 ITKDKALKLIEINLEELCTAA----RCGDEFEICTIINAKSGRCSENCKFCAQSAHYIEKYPLKTMLSAAKKDDAAGVQRFSPVTSGKRL--KKSEVESLCKSMKEIKKNTNLKICASCGLLDFKKLKEAGLTRYHNNMESSKNFFKT-VCSTHTVEDKIRTLQFAKQQGLEICSGGIMGLGEDRIDMAFTIHELGA--VSIPINMLNPIPGTPFMRRICAIYRFINPKAFIRLAGGRDKGRS-CLQSGANALISGD-MLTTSGITIKRDLQMINYHVSK- Pench1 WTRDEVKQIYETPLSQLTYAAAAVHRDPSAIQMCTLMNIKTGGCSEDCSYCAQSSKHLKATKMDEVLTKARNAKANGSTRFCMGAAWRDMRGRKTSLKNVKQMITGIR-EMNMEVCVTLGMIQAKELKEAGLTAYNHNLDTSREFYPT-IITTRSYDERLKTLSHVRDAGINVCSGGILGLGEDRIGLLHTVSSLPAHPESFPVNALVPIPGTPLLLRTVATARIVMPSTIVRLAAGREEQQVACFQAGANAVFTGEKMLTTDCNGWDEDRAMFGYYPMKS Phybl2 WSREEIQAIYDSPFMDLMYFGAKVHRNAREVQQCTLLSIKTGGCTEDCKYCPQSSRYVKAQKMDEILKAALRAKDAGSTRFCMGAAWRDLAGRKSNFSKILNNVKTIR-GMGMEVCCTLGMLQAKQLKEAGLTAYNHNLDTSREFYPK-IITTRSYDERLETIGHAQDAGISVCSGGIIGLGEDRVGLLHTLSTLKQHPESVPVNALLAVPGTPLMVRMIATARIAMPKSMVRLSAGRVSEQAMCFMAGANSIFTGDKLLTTPNNDATEDQKMFGLVPKPP Picst3 WSKEQIKEIYDTPLMELVFQSQLQHRNPAEVQLCTLLSIKTGGCTEDCKYCAQSSRYTKAEKLEEVMEKARIAKMNGSTRFCMGAAWRDMAGRKSGLKKIGEMVKRINDDLEMETCVTLGMVQAEELARSGLTAYNHNIDTSREHYPS-VISTRTFDDRLQTIKNVQKAGIKACTGGILGLGEDHISFLHTLATMEYHPESLPINRLVPIKGTPMILKTIATARLIMPHSIIRLAAGREHEQFLCFMSGCNAIFTGEKMLTTMCNGWDEDIEMLGLRPMKS Plicr1 WSKQEIQQIYNTPLLDLVFRSAAVHRDPTKIQLCTLMNIKTGGCTEDCSYCSQSSKHTKASKLEPVLEAARKAKENGSTRFCMGAAWRDLAGRKSGFARILTMVKEVR-GMGMEVCTTLGMLQARQLKEAGLTAYNHNLDTSREFYPS-VITTRSYDERLDTISNVRDAGISVCSGGILGLGEDRVGLIWEVSNMPEHPESFPVNALVPIPGTPLLIRTIATARVVLPGTIIRLAAGREAEQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLDGMQS Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 WTKEQVKDVYESPLMELVFRAATTHRDPSKVQLCTLLNIKTGGCTEDCSYCAQSSRYLQASKLEPVLAEARKAKANGSTRFCMGAAWRDMNGRKNGFKKILEMVKEVR-AMGMEVCTTLGMLQAVQLKEAGLTAYNHNLDTSREYYPK-VISTRSYDERLQTIENVREAGLSVCSGGIIGLGEDRIALICQMSQLPAPPESFPVNALVPIPGTPLILRTISTARIVLPTSIVRFAAGREAEQAMCFMAGANAIFTGEKMLTTPTSGWDEDISMFGITPLGS Punst1 WSKQEIQKIYDSPLLDLVFRAATVHRDPGQVQLCTLMNIKTGGCSEDCSYCSQSSRYTKASKLEPVLEAARKAKENGSTRFCMGAAWRDLAGRKRGFERILTMVREVR-GMGMEVCTTLGMLQAKMLKEAGLTAYNHNLDTSREHYPK-VITTRSYDERLDTISAVREAGISVCSGGILGLGEDRVGLIWEVSNMPEHPESFPVNALVPIKGTPLLLRTIATARIVLPTTIIRLAAGRENEQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLEGMRS Rhior3 WTREEIQSIYDSPLMELLYHGAKVHRNGREVQQCTLLSIKTGGCTEDCKYCPQSSRYVKAQKLDEILYAAQRAKDAGSTRFCMGAAWRDLAGRKSNFNKILDHVKVIR-SMGMEVCCTLGMLQAKQLKNAGLTAYNHNLDTSREFYPK-IISTRSYDERLKTIDNAQRAGISVCSGGIIGLGEDRVGLLHTLSTLPQHPESVPVNALLAVPGTPLMVRMIATARIIMPKSMVRLSAGRIPEQALCFMAGANSIFTGDKLLTTPNNEVSDDKKMFGLVAKPP Rhoto1 WTREQVQEVYDSPLMELIFRAASVHRPPDQVQLCTLLNIKTGGCSEDCSYCAQSSKYLKAEKLETVLAEARKAKENGSTRFCMGAAWRDMSGRKRGFERILKMVEGVR-AMDMEVCTTLGMLQAQKLKEAGLTAYNHNLDTSREYYPK-VITTRKYDERLETIEAVRSAGISVCSGGIIGLGEDRVGLIYEMSQLPEPPESFPVNALVAIPGTPLLLRTIATARIVLPTSIIRFAAGRETEQAMAFMAGANAIFTGERMLTTPTSGWDEDHAMLGLKGMGS Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 WTKSQLKEIYHTPLLELTHAAQLQHRDPTKVQLCTLMNIKSGGCSEDCKYCAQSSRNLKAEKMDEVIKEAEEAKRNGSTRFCLGAAWRDMKGRKSAMKRIQEMVTKVN-DMGLETCVTLGMVQAKQLKDAGLTAYNHNIDTSREHYSK-VITTRTYDDRLQTIKNVQESGIKACTGGILGLGEDHIGFIYTLSNMSPHPESLPINRLVAIKGTPMILRTIATARIVMPKAIIRLAAGRETEQFVCFMAGCNSIFTGKKMLTTMCNGWDEDKAMLGLQPMEA Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 WTKQEIQSIYDSPLLDLVFRAAAVHRDPRKVQLCTLMNIKTGGCSENCSYCSQSSRYTKASPLEPVLEAARKAKANGSTRFCMGAAWRDLAGRKRGFERILTMVREVR-GMGMEVCTTLGMLQARKLKEAGLTAYNHNLDTSREFYPE-VITSRSYDDRLDTISAVRDAGISVCSGGILGLGEDRVGLIWEVANMPEHPESFPVNALIPIPGTPLLARTIATARIVMPTTIIRIAAGRESEQMMCFMAGANAIFTGEQMLTTPCSPWDQDKAMMGLEGMES Schpo1 WTREEIQKIYDTPLIDLIFRAASIHRDPKKVQQCTLLSIKTGGCTEDCKYCAQSSRYVKATKLDEVLEKAKIAKAKGSTRFCMGSAWRDLNGRNRTFKNILEIIKEVR-SMDMEVCVTLGMLQAKELKDAGLTAYNHNLDTSREYYSK-IISTRTYDERLNTIDNLRKAGLKVCSGGILGLGEDRVGLIHSLATMPTHPESVPFNLLVPIPGTPVFLRSIATARICMPKTIIRFAAGRESEQALAFMAGANAVFTGEKMLTTPAVSWDSDSQLFGLEGMQS Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar WELEEVIELYNTPLMELVYKAATTHRNPKEIQQCTLLSIKTGGCTEDCSYCSQSSKHVKPTPTEDVIENARKAKAAGSTRFCMGSAWREV-GKKHAFKKVITMVKEVN-SMGMEVCTTLGMLQAKELKAAGVTAYNHNLDSSREFYGK-IITTRSYDERLKTLENVRAAGISVCCGGIIGMGEDRIGLLHTLSTLNEHPESVPVNALVAVDGTPLMVRMIATARCLMPKSMVRLSAGRTSEQALMFMAGANSIFTGDKLLTAPNPEFDEDKLMFGLQGKPA Spipu1 WTKQEVQDIYDSPLMELLFNAAKVHRNPREVQQCTLLSIKTGGCTEDCAYCPQSSKYVKASKLDTVLAAAKKAKEAGSSRFCMGAAWRDLHGRKTNFNTILNYVKEIR-SMGMEVCCTLGMLQAQQLKEAGLTAYNHNLDTSREYYPK-IITTRSYDERLETIANVRDAGISVCSGGIIGLGEDRVGMLWTLATMVEHPESVPVNALLAVEGTPLMVRMIATARIVMPTSMIRLSAGRQPEQALCFMAGANSIFTGDKLLTTPNNAYTDDQKMFGLVPKQA Sporo1 WSRQEVQEVYDTPLFELIFRAASVHRPPDQVQLCTLLNIKTGGCSEDCSYCAQSSKYLKAEKLETVLTEARKAKENGSTRFCMGAAWRDMSGRKRGFERILKMVEGVR-ALDMEVCTTLGMLQAAQLKTAGLTAYNHNLDTSREYYPK-VITTRKFDERLETIEAVRSAGISVCSGGIIGLGEDRVGLIWEMSQLPEAPESFPVNALVAIPGTPLLLRTIATARIVLPTSIIRFAAGRESEQALAFMAGANAIFTGERMLTTPTSGWDEDHAMLGLKGMRS Stehi1 WARDEVQKVYETPLLDLVFRAAAVHRDPTKIQLCTLMNIKTGGCTEDCSYCSQSSKYTKASKLEPVLEAARKAKANGSTRFCMGAAWRDLAGRKSGFKRILEMVTEVR-KMDMEVCTTLGMLQAQQLKEAGLTAYNHNLDTSREFYPK-VITTRSYDERLDTISAVRDAGISVCSGGILGLGEDRVGLIWEVSNMPEHPESFPVNALVAIPGTPLILRTIATARIVLPKTIIRLAAGRESEQAMCFMAGANAVFTGEQMLTTPCSPWDEDKAMMGLEGMKS Tapde11 YTKEEIAEIYKKPLLDLVFEASSIHRDPHEIQLCTLLNIKSGGCSEDCSYCSQSSRYSPVTKLDDVLVKAREARDNGSTRFCMGSAWRDMNGRKANLKRICEMVTEIR-GMGMEVCTTLGMLQAKDLKEAGLTAYNHNIDTSKEFYPS-VITTRSFEERLNTIDNVKKAGIKVCSGGILGLGEDRISFLQTLSGIK--PESLPINALVPIEGTPLIVRTIATARILLPKTIIRLAAGRETDQAMCFMAGANAVFTGERMLTTACSGWDEDKSMLGLRGMES Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 WTKREIQDIFDGPLMEIIFRAATVHRDPSRIQLCTLMNIKTGGCTEDCKYCSQSSSYTKASRLEPVLAAARKAKENGSTRFCMGAAWRDLAGRKSGFEKILTMVKEVR-GMGMEVCTTLGMLQAKRLKEAGLSAYNHNLDTSREFYPEKVITTRTYDDRISTIEAVRQAGISVCSGGILGLGEDRVGLIHELSTLSEHPESFPVNTLVPIEGTPLVLRTIATARMVLPTTIIRLAAGRETEQAMAFMAGANAIFTGETMLTTPCSGWDQDKAMLGLRGLRS Trire2 WTREEIAAIYYQPLLELTYQSGSLHRAPGEVQLCTLMNIKTGGCSEDCSYCAQSSRYLEAKKMESVLEAARQAAANGSTRFCMGAAWRDMRGRKSGLKNIVEMIKGVK-ALGMEACVTLGMIQARQLKDAGLTAYNHNVDTSREFYPS-VISTRSYDERLATLGHVRDAGINVCSGGILGLGEDRVGLLHTVSTLPKHPESFPVNALVPIKGTPLMLRTIATARLLMPATIIRIAAGREEKQALCFMAGANAIFTGEKMLTTECNGWDEDSAMFGLEPMKS Umbra1 WV------------------------------------------------------------W-----------------FCMGAAWRDLAGRKSNFNKILGYVTEIR-GMGMEVCCTLGMLQAKRLKDAGLTAYNHNLDTSREFYPK-IITTRSYDERLETISHAQGAGISVCSGGIIGLGEDRVGMLHTLSTLGQHPESVPINALLAVEGTPLMIRMIATARIVMPKSMVRLSAGRQSEQAMCFLAGANSIFTGDKLLTTPNNEFTDDQKMFGIVPKPP Ustma22 WSRKEVQRIYDSPLLELVFRSANVHRPVNRVQLCTLMNIKEGGCSEDCGYCSQSSKYSNASKLETVLTEARKAKANGSTRFCMGAAWREVGGRKRGFNRILDMVREIR-GMGMEVCTTLGMLQAKQLKEAGLTAYNHNLDTSREYYGK-VVTTRSYDDRIGTIANVREAGISVCSGGILGLGEDRVGLIWEMSTLPEHPESFPVNALVAIPGTPMMLRTVATARIVLPGSIIRLAAGRESEQAMAFLAGANAIFTGERMLTTPTSSWDEDKAMLGLRGMQS Walse1 WNRNEIQSIYQQPLLELVYRAASVHREPGRVQLCTLMNIKTGGCSEDCSYCSQSSRYTEAGKLDPVIQEAKRAKEAGSTRFCMGAAWRDVGGRKRGFDRILAMVREIK-GMGMEVCTTLGMLQAIALKDAGLTAYNHNLDTSREYYPE-VITTRSYEDRLSTIANVRDAGISVCSGGILGLGEDRVGLIWELSRLPEHPESFPVNALVPIKGTPLVVRTIATARIVMPKSIVRIAAGRDAEQAMCFMSGANAIFSG-YMLTTDGVEKDQDAELFGLQPMKP Zygro1 WTKEQLATIYHTPLLELVHQAQRQHRDANKVQLCTLMNIKEGGCSEDCKYCSQSTRHVQASKMDDVIKEAQEAKRNGSTRFCMGAAWRDMQGRKSALGRISQMVSAVN-EMGMETCVTLGMLQARQLKKAGLTAYNHNVDTSREHYSK-IISTRSYDDRLKTIKNVQDSGIKACCGGILGLGEDHIGFLHTLANMTPHPESLPINRLVPISGTAIILRTIATARIVMPQSIIRLAAGRDNEQFLCFLAGCNSIFTGKRMLTTMCNGWDEDKALLGLEPMEA [Cluster3126.fasta_al_trimmed; alignment length = 101] Allma1 VESVENDIQLGEFQ-DALTVAEVHHYLAAQTLNKMAQYCEQFSQFNSPAMVVEVRLYEFEMAQIANFLCDSVEEMRTLVPSLRVDETQLQELLHRLANIRK Ashgo11 ----------------------------------------------------------------------------------------------------- Aspfu1 ELEAASTLKLGADQ-NTLSLSEARLVINPENLTKTLDYLEVFARFKDEENIKAVELEMFERSQLGSLCCDNAEEAKSLIPSLKISDADLQELLDELTKLRN Aurde31 EEEDAASLKLGEFN-NALLISEVKLLLDTAVYNKTLEYVKTFAKFSTAESASAVRLTQFETAQLANLVPADVDEAKSIVPSLKIDDDRLQSLLDEVQTLRK Batde5 EEEDANLSKFGEFQ-DVLLISEVRVLLESDIMQKTIDYCQQFSRFTNKQTVKEIRFHQFEMAQLANLCCETAEEAKVLIPSLK-HDDELQNLLNDLQALRK Botbo1 EEEDADALKLGEFN-NALLISEVKYLLETPVFNKTLDYVRTFAKFNTSDTASAVRLTQFETAQIANLCPVDAEEAKNLIPSLKLEDDRLQVLLDEVQAMRK Botci1 DEEASTVLKLGEFQ-DVLTHSEAALVINTEILSKTQEYLDHFARFKRKENVEAVELAKFERAQLGSLCCDTADEAKTLIPSLKISDDDLTELLDEITKLMG Caeel VEEDAAECKFPEFE-TTLLTAEVYLLLESEVFIKTLNYARRMSRFKNRETIRAVRLHKFEVAQIANLCPENAEEAKALVPSLKIEESELEEVLKDLQSKRT Canalb1 ----------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------- Capow DEESAADLRLTKFE-KALFPAEVKLILETNTLEKTLAYVQAFPQYKNTETAREVRFRQFEIAALASLCPEQAEEAKALVPSILISDEELQNVLDELNSMKD Catan2 DLEAGEVLRLGDLQ-TALTVSEVHHFLKAANVAKFEQYCEKFNQFNSSSTVVELRLWEFEIAQIANFLVDSPEELKSLVPSLRIDDAPLQELLDTLRNVQA Cioin QEEDSSQLQFPEFE-SALLNSEVHMLLESEVFMKTLNYTQRFSRFKNRETITSVRLHKFELASLANLCPETAEEAKALVPSLRFEDEDLQQVLEDIQTKRS CocheC53 ----------------------------------------------------------------------------------------------------- Coere1 ETLDAARLELGDFQ-DALLISEVKVLLEDEVYSKTLEYVQKFSRYTNRDTIKEVRLEPFECAQLGNLCCSEYEEAKSLVPSIKISDDDLDSLLKQMDSLKK Conco1 IETDATILELGDFN-NILSVAEVGILLDTKTFNSTLEYAKKFSRFSAAESVKDVRFAHYEVAQLVNLCCDTAEEAKTLIPSLKMNDPELEGLLTSMLTYKK Conpu1 ----------------------------------------------------------------------------------------------------- Copci DEEDAATLKLGEFN-NALLISEVKYLLETAVYNKTLDYVKTFAKFNTTDSASAVRLTQFETAQIANLCPASAEEAKSIIPSLKIDDDRLQALVDEIQTMRK Croqu1 QEEDASQLKLGEFEGATLSISEVKLLLETAVYKKTQEFVNQFARFTTTDSAQAARLRPFELAQLASLCPEEAEEAKSLIPSLNKDDDALQAILNEISGLKR CryneH991 QEEDATKLQFGDFA-EGLTLTEVATLLKNKVYQSTTDYVNEF---TTMDVSDSMRLNKFEIAQIMSLRPERVEVAVALIPSLDENEAQLQSLLDDVRAMVR Crypa2 DEQAGAELKLGEFE-NVLTLSEASLVINSEILSKTIDYLDAFARFKQKENVEAVELNKFERAQIGSLCCDSAEEAKTLIPSIKIDDDVLQELLDQMAKLQG Debha1 ----------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------- Dicdi EEEDLTTLKFPDLK-DALLNSEVAILLEIRTFHKTLAYAEKFSRYKNKTSIKQVRLEEFEIASLANLCPEISDEAKSLIPSLKMEDDELQAILDELSNLRK Dmel -DEDAADLQFPEFE-NALLISEVHMLLDSEVFMKTYAYTDSFRKFKNKETIMSARLHKFELAALGNLCPEAPEEAKALIPSLRFEDEELRQILDDIGTKRS Enthi ----------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------- Fomme1 QEEDASVLKLGEFN-NALLISEVKYLLETVVYNKTLEYVKQFAKFTTTDSASAVRLTQFETAQIANLCPADAEEAKSIIPSLKIDDDRLQALLDEIQTMRK Fusgr1 NEEATAVLNLGEFQ-DVLTLSEAALVLNTEMLNSTLTYLDNFARFTQKENVEAVELAKFERAQLGSLCCEGADEAKTLIPSLKISDQDLQDLLDEISKLQT Galma1 EEEDASALKLGEFN-NALLISEVKYLLETAVYNKTLEYVKTFAKFNTTDSASAVRLTQFETAQIANLCPANAEEAKSIVPSLKIDDDRLQALLDEIQTMRK Ganpr1 ELEDAKSLKLGDFQ-DSMSYPEALLLLETDVFDKSLQYVKRFAKFVGRESVAEIRFHSFEVAELLNLCPETAEEAKSWIPTLRFKDIELKSYLDDLNALRQ Gloin1 EEEDAAKLKFGDFE-DELFISEVALLLENTVYKKTEELVNTFTRFHNDESVRELRLHKYELAQLANLVCEEIDEAKSLIPSLKRSDEEIRAMLDDISALKK Hisca1 ELEATSQLKLGEFQ-NVLSLSEARLVINREALVKTQDYLELFARFKEKENIEAVELEFFERSQLGSLCCNDAEEAKSLIPSIKISDTELQELLDELTKLRN Klula1 ----------------------------------------------------------------------------------------------------- Lacbi2 EEEDASALKLGEFN-NALLISEVKYLLETAVYNKTLEYVKTFAKFNTTDSASAVRLTQFETAQIANLCPADAEEAKSVIPSLKIDDDRLQALLEEIQTMRK Lenti61 EEEDASTLRLGEFN-NALLISEVRYLLETAVYNKTLEYVKTFAKFDKPEAATAIRLTQFEIAQIANLCPVTAEEAKSIIPSLKIDDDKLQPLLDEIQTMRK Malgl1 EVEDASTGKLGEFQ-DALLVSEVHLFFSSAVTQKTKEYVDEFSRYKDQSTIREVRLTQFEMAQLANLSVTDIDEARTLIPTLK-DDAQLESLLHELTAIRS Mellp23 QEEDASQLKLGEFD-AALSISEVKLLLETAVYKKTQEFVNQFARFSTTDSAQAARLKPFELAQLASLCPEEAEEAKSLIPSLAKDDDALQAILNEISGLKR Mnele EDEDAAQLKFPEFK-TALLISEVHMLLKSAVFNKTLEYTEKFSFYQNRETIKAVRLHKFEAACLANLCPDNYEEAKALIPSLSFFNFDFVLCYSD------ Monbr ----------------------------------------------------------------------------------------------------- Morel2 EDEDASTLKLGDFQ-DALFVSEVKILLDSEVYQKSLNYVTQFNRFTNPDVVREVRLTGFELAQLANLCCEEAEEAKALIPSLKIDDETLQNFLNQTLDLKK Mucci2 DQEDASNLKLGEFD-GALYISEVRIILEN-VMAKTLDYVRAFSRFSNIESVREVRMAQFEVAQIANLCCEDAEEAKALIPSLKVEVPELQEMLSQMLTIKK Mydma EEEDATELQFPEFE-SALLNSEVFMLLESDVFMKTLNYTQRFSRFKNRETIAQVRLHKFELACIANLCPENAEEARTLIPSLRFVEEELQQILDEIKTHRS Neucr2 EEEASAVLKLGEFQ-DVLTLSEASLVINTDVLNKTLDYLDAFARFKQKENVEAVELTKFERAQIGSLCCDSADECKTLIPSLKITDDELQELLDEMAKLMS Orpsp11 ----------------------------------------------------------------------------------------------------- Pench1 ELEAASTLKLGADQ-HTLSLSEARLVIHPENLTKTLDYLDVFARFKDEENIKAVELEMFERSQLGSLCCDNAEEAKSLIPSLKISDGDLQELLDELTKLRN Phybl2 EQEDATTLKLGEFA-NALYISEVRILLEN-VMQKTLEYVRAFSRFSNRDSVREVRLAPFEMSQLANLCCEDAEEAKALIPSLKVEDDQLQEMLNQMLTIKK Picst3 ----------------------------------------------------------------------------------------------------- Plicr1 EEEDAAALKLGEFN-NALLISEVKYLLETAVYNKTLEYVKTFTKFNTTDSASAVRLTQFETAQIANLCPASAEEAKSVVPSLKIDDDRLQALLDEIQTMRK Polpo ----------------------------------------------------------------------------------------------------- Pucgr2 QEEDASQLKLGEFD-MALSISEVKLLLETAVYKKTHEYVNQFARFNSTDSAQAARLKQFELAQLASLCPEEAEEAKSLIPSIGKDDDALQALLNEISGLKR Punst1 ----------------------------------------------------------------------------------------------------- Rhior3 ELEDATNLNLGEFS-GALYLSEVKVILDNAVLAKTLEYVRNFSRYNTIDSVREVRLTQFEVAQMANLCCEEAEEAKALIPR-------------------- Rhoto1 DDEDASRLKFPSFG-DELTISEVKLVLENAVYNKTKDYVDTFARFYDHETASNVRFQFFEQVQLVNLCPMEAEEAKALVPSI-VEDDQLQQYLDDMTRARK Rozal11 V------------------------------------YNQALNKFKNKEVAKNIKLSHFEAVQLLNLCPDSIDETKSLIPSIKKTDDQIQRILNEIDNSRR Sacce1 ----------------------------------------------------------------------------------------------------- Salro VVEDANSLEFFDFE-QVLLLSEVEKILESAEFTKTLDYAQRFRSYEADEALRSIMLHKFEEVQLINLAPETVEEAKALIPTLRVDDDILENVLQQIMAFRS Schco3 EEEDATTLKLGEFA-QALLISEVKYLLENAVYAKTLDYVKTFAKWHTTDSASAVRLTQFETAQLANLCPAEAEEAKSIIPSLKVDDDRLQALLNEIQTMRK Schpo1 -EEDAAQLKLGEFE-NELTVSEAKILIETDVMKKTVAYFNVFARFKTAEATYACEFHKFERAQLGTLCCEDAEEARTLIPSLKIDDQNLQGILDELSTLRK Sorma EEEASAVLKLGEFN-DVLTLSEASLVINTDVLNKTLDYLDAFARFKQKENVEAVELTKFERAQIGSLCCDSADECKTLIPSLKIDDENLQELLDEMAKLMS Sphar -------------------------------------------PFKNKESVASVRLKEFEKASLANLTPKEEGEAKYLVQSLRVKGDELTNLLDEVNVFQS Spipu1 EDLDSATGKLGDFQ-GVLLIPEVKLLLDNEVFEKTLEYCSRFTAFSNPNTVRHIKYEPFEIGLMGNLGIESVEEARSLIPSLTLDDNTIHSTLNDLQNLKK Sporo1 ----------------------------------------------------------------------------------------------------- Stehi1 ----------------------------------------------------------------------------------------------------- Tapde11 ----------------------------------------------------------------------------------------------------- Thetr EGSSAAMRAFGDFA-EALMLAEVATVLKKDTFLKTLEYAQRFNHITEMQSIMDTRLEPVQLAAMANLMPRSVAEARSLIPSLACSDDVLEGLINRLQELQR Treme1 VEEDATKLQFGDLA-DGLTLTDVNTLLENKVYKSTVEYVSTF---ATPDAVESMRLNKFEIAQIMYLRPERIEVAIALIPSLDAKETLLQQLLDDVRNISR Trire2 NEEAGAVLNLGEFQ-DVLTLSEAALVLNTEMLNQTLNYLDHFARFTQKENVEAVELAKFERAQLGSLCCENADEAKTLIPSLKISDEDLQDLLDEISKLQN Umbra1 EEQDAAQLKLGEFQ-NALFISELNILLEN-VLQKTVSYVQSFSRFTNRDSVREVRLSQFEIAQLANLCCDDSEEAKALIPSLKIDDDRLQELMNQMLTIKK Ustma22 EDEDAAIGKLGEFD-DILLISEVELVFSTAVFSKTKDYVSEFSRYKDPNTIREIRLTQFEMAQLANLCITEVDEAKALIPTLR-DDALLDSLLQELDNIRR Walse1 DDEDASKLKLGEFN-DMLTISEVKHLLDTPVFKKTSEYVNTFTVFGSKESAISVRMTQFEQAQIGNLVPGDVEEAKSLIPSLEHDEMTVQTILDELDALRK Zygro1 ----------------------------------------------------------------------------------------------------- [Cluster3130.fasta_al_trimmed; alignment length = 46] Allma1 NGLFRRNSVFVGAIFATAFTFEIFFDWDSRNKGKQWKDI-KDNYA- Ashgo11 NTLFRRNSVFVGTIFASAFVFQTAFDYEKHNKGKLWKDV-KLQLQN Aspfu1 ---------------------------------------------- Aurde31 NTIARRNSVFASTIFAGAFAFGVGLDWDRWNKGKQWKDI-RDRYIQ Batde5 ---------------------------------------------- Botbo1 NSIARRNSVFVSSIFASAFAFSIGFDWDSWNKGKQWKDI-RHKYVE Botci1 NFLFRKNYVFLGAVFGAAFGFEMAYDWDSINKGRQWKDI-RARYVE Caeel NTVSRRFSTILLASAFGAYTFNYTLEWDTKNSNKQWKDI-KQQLAQ Canalb1 GRLLERNSIYVATIFGGAFAFQGFFDWEEHNKAKLWKNV-KGKFLE Cangl KVLFKRNSIFVGTILASAFVFQGAFDYENHNKGKLWKDV-KAQIGA Capow QLAFKRNSVYITGIITGAFIFEKVFDFAKLNEGKSFEDLKKARNLQ Catan2 NSAFRRNSVFVGIIFATAFTFEVGFDWDSRNKGKQWKDI-KDNYQ- Cioin ---------------------------------------------- CocheC53 SAVLRSNTTMLFTVFGAAFGLQLAFDWDRVNRGRQWKDI-KHRYME Coere1 RNFFKKESVYFTTIVASGVAFSVTFNWDKKTAGTKWEDI-KGDYVA Conco1 STLFKRNSVFLVGIFSAAFAFELVFDWNKMNKGKQWEDV-KHRFVQ Conpu1 NAVAKRNSVYVSAIFASAFGFSVGFDWDKWNQGKQWKDI-RQKYIQ Copci NTIFKRNSVFVSTVFVGAFAFGIGFDFDYWNKGKQWKDI-RHKYVQ Croqu1 NTFMKRNAVFVSTIFAGSFAFSIGFDWERHNRGKLWADI-RDKV-- CryneH991 NTFFRRNSVFVATTFITAFTFSMGFDWDSHNRGKQWKDI-RHKYLE Crypa2 ---------------------------------------------- Debha1 SALFKRNSVYVATILGGAFAFQGFFDYENHNKGKLWKDV-KGKFLE Dekbr2 QTVFKRNSVYVGTIFGTAFVFQTVFDWETRNKGKLWKDV-KVKLAA Dicdi KYVARRNSTWMAGAILGAFVLDSTVSFDSVNKGKLWKDV-YAERVK Dmel NTLFKRTSTYAVAIIASAFFFERALDFEGINKGKLWKDI-KGKYE- Enthi ---------------------------------------------- Falba YGVFRRNSTFLLAVFASAWVFESVFDMNHYNKGRTLQEV-LPSFVE Fomme1 NTFFRRNSVFVSSVFVGAFAFTMAFDWDRWNQGKQWKDI-RHKYVQ Fusgr1 ---------MLATVFSAGFAWEIGFNWDNHNRGRQWKDI-RHKFIE Galma1 ---------------------------------------------- Ganpr1 NAVLRRNTTFFGLVFASAFALEIVFDWDRINAGRQWKDI-RGRYIQ Gloin1 RTLFRRNSVFLLGIFASAFAFEMAFDWDRINKGKQWKDI-KDRFSQ Hisca1 NSLFRRNTTFLSSIFIGAFAFEMAFDFDSLNKGRQWKDI-RHQYIQ Klula1 KTVFKRNSVFVGTVFASAFVFQAAFDYENHNKGKLWKDI-KGGIMN Lacbi2 NAIFKRNSVFVTTVFAGAFAFGIGFDYDTWNKGKQWKDI-RDKYVQ Lenti61 NALVKRNSVFVPVIFTGAFAFSVGFDWDARNQGKQWKDI-RAKYIE Malgl1 ---------------------------------------------- Mellp23 NTFMKRNSVYVSTIFAGSFAFSLSFDWENHNRGKLWSDI-RDKVCK Mnele ---------------------------------------------- Monbr ---------------------------------------------- Morel2 ---------------------------------------------- Mucci2 NTFFKKNSVFVTSIFVGAIAFEVAFDWDHLNKGKQWKDI-KDKYVS Mydma ---------------------------------------------- Neucr2 NLIFRNNTAFVGAVFAGAFAFELAYDWDKINKGRQWKDI-RHKYVE Orpsp11 ---------------------------------------------- Pench1 QTFIRKNTVLLTTAFAGAFAFELAFDWDSWNQGRQWKDI-KHRYMV Phybl2 NTIFKKNSVFVTSIFVGAIGFEMAFDWDNVNKGKQWKDI-KDKYEQ Picst3 ---------------------------------------------- Plicr1 NALVKRNSVYVSSIFIGAFAFGVGFDWDSHNQGKQWKDI-RDKYTS Polpo ---------------------------------------------- Pucgr2 ---------------------------------------------- Punst1 NTLVKRNSVYVTSIFAGAFAFGIGFDWDTWNKGKQWKDI-RAKYIE Rhior3 TSLFKKNSVFVTTVFAGAIAFEVGFDWDDINKGKQWKDI-KDKYE- Rhoto1 ANLFARNSVFVGTVFTGAFAFGIVYDWDAHNAGKQWKDI-RHKYVE Rozal11 ---------------------------------------------- Sacce1 KTFFKRNAVFVGTIFAGAFVFQTVFDYENHNKGKLWKDV-KARIAA Salro ---------------------------------------------- Schco3 NVFFKRNSVFASTVFAGAFFFGVGFDYDKWNAGKQWKDI-RHKYVE Schpo1 NIFFRRNSSFYATIFVSAFFAKIGFDWKRANAGLTWDEV-KPRFLN Sorma SLLFRKNTAFLGAVFAGAFAFEVAYDWDKINKGRQWKDI-RHKYVE Sphar RTCMRSNASFMATFLVAGVFAEQVFEYDNYNKGKLWKHI------- Spipu1 NVFFRRSSAYLAGIFASAFAFEIAFDWDSINKGRQWKDI-RDKYIQ Sporo1 ---------------------------------------------- Stehi1 NAFVKRNSVYVSTIFVGAFAFGVGFDWDTWNKG-----V-RPPLHL Tapde11 NTVFKRNSVFIGAVFATGFVFKISFDWDRVNAGKQWKDI-RGKYVE Thetr ---------------------------------------------- Treme1 NTFFRRNSIFVTTVFLGAFGFSMGFDWDAHNRGKQWKDI-RDKYVQ Trire2 -TVFRKNWTMLAAVFGAGFAWEIGFNWDSNNRGRQWKDI-RHKYIE Umbra1 NTLVKKNSVFVATIFASAFAFEVAFDWDSLNKGKQWKDI-KDKYVQ Ustma22 NTVFKRNSVYVGSIFFGAFAFGIGYDWDAHNKGKQWKDI-RGKYLE Walse1 NTLFKRNSTYVATIFVGTFAFGVGFDWDKHNAGKQWPEL-RAKILA Zygro1 RVLFKRNSVFVGTVLASAFVFQASFDYETHNKGKLWKDV-KLQLQE [Cluster3144.fasta_al_trimmed; alignment length = 171] Allma1 --GANTHGQLATGATLDTIQGGANHTLLV--AAGSNHDSQLGVACGWAHSAAVGDLYVWGDN------RVACGLRHTATITLYMWGANRHGQCCGSHHTIALAFGH--NKFGQLWTTSAIVGRAHADSQWFVLGSEHCV--LVAWGWNEHGNCGGKR-VIGGGYAHTMAVL Ashgo11 ALGSNGSGQLGIGHYKDKIACGGNHSLMLMEAAGDGRQGQFAVACGWDYSVVIGNVLACGAGLNGELG-VYSSFQNVVLRDLYGWGPNRKGQLMGKDFIAIVRINDIIRDISSEWSSLHIWG-NGNYGQMFAAGSEHGVMSVFCWGWGEHGNCGEK--IIQGGCATSWVCT Aspfu1 AFGSNGSGQLGIGHDEDCIVAGGNHTLILYQAAGCNEDGRCGLSATWEGTFLVDSIFVIGSGAKGELGSIASGMGHTVVVLVYGWGGARKGQLCGREFTVVSIIGSCDNKWNILWHGVYVHG-RNDRGQLLAVGSEHVLALVVAFGWGEHGNCG----VIGAGCATSWIIT Aurde31 SSGSNAHGQLAHGTVDDDIACGANHTLLLLRVVGDGSHGQLGIAASWESSYVVDILLSFGSNVLGELGALSSGPRHVLCLVLIGWGASRHGQLCGNQHTLLLGLGS--NRKGQLWNTSFLVG-SGDHGQLIAAGSEHALVLIYGWGWNEHGNLGGA--CIWGGCGTSWISI Batde5 TAGSNAAGQLGTGSLNDQLAGGANHSILLDSVCGDNAHGQLGIACGWQVSFAVGAVWVAGCNLYGQAGKTACGLRHTLFLGLWGCGSNRYGQLCGQNHSIALTFGQ--NKHGQLWSTSGVVG-RNDHGQLIAAGSEHIIAICISWGWNEHGNCGGI--SVGAGAGHSLIWT Botbo1 SAGSNAQGQLANGTQDDEIASGANHALLLLEGCGDGSKGQLGVAASWETSFVIDVLLSMGGNDFGDLGHLTAGPHHVILALIVGWGSSRHGQLLGNQHSVVLDLGS--NRKGQLWNGTYLLG-SQEKGQLFACGSEHVLALVWAWGWNEHGNLGGR--AVWAGCGTSWILV Botci1 AIGSNGSGQLGIGHKEDQIRAGGNHTLMLSTCSGDSSNGACGCAATWEASIIVTKIYSFGTGNKGELGDLATSVSHVVAVLVYGWGSGRKGQICGREFTYLLILGS--DKWNIRWGSILLLG-KNDHGQLIAIGSEHGLALVCAWGWGEHGNCGAS--IIGTGCATSWICL Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -----------------KIAGGGNHTMVILDTCGSNEFGQCGISCGWEFSILVGEVYVCGRGLKGELGEIKSCMQHTIIQTLVGWGNSRKGQLLGREFTAIQIFGKSSIKNIPEWSSVHILG-NNSHEQLYAIGSEHGLV-VYAWGWSEHGNCGAK--VIGAGCATSWVVV Cangl -----------------KISCGGNHTVILLSGCGDNSLGQLCVTCCWDSTTIVGKVYSRGSGLKGELGRVYSSFQNCILVLVYAWGNNTKCQIMGKDFNLLMVNGKTPEDFTKDWSSIHIRG-NNIHGQVFTTGSEHGILVLSCWGWGEHGNCGSR---VYGGCATTWIVS Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 AFGSNGEGQLGLPAAEIAIRGGDNHTLILCKGVGDNRKGQLGIAATCESSAYVSYIYTEGTGQWGELGDFSAGVWHYVTVLVYGWGKARLSQLCGKDFTYLVLLGK--DKFNIIWHAIFVLG-KENMWKLIAVGSDHVLAVLISWGWGKHGNCGGE--VIGAGFCTSFVIT Coere1 ALGSNSSGQLATGDLEDHVCGGGNHAFAWPSACGSNKDGELGVACGWNHTLLLGDLYATGSNGFGQCSSIACGMRHSLALSVYGWGAGRAGQLCGRSHSVLLVSGQ--DKYGQCWEFCAALG-RSDHGQLLTCGSNHVVVMVFMWGWNEHGN------------------- Conco1 SFGSNGNYQLGLAHDEDDIKAGGNHTLILLSGVGDNSSNQLGISCGWSHSVLIGIAYGIGSNQFGQLGKAGSGLRHTLLLTCYASGSNKFGQLCGERHTVMLSFGN--NRFFQLWQHTIALG-GNDHLQLSYAGSAHTLALLLVWGWNEHGNCHTK--IIFGGCATSFIAF Conpu1 AAGSNARGQLASSTYEDKLVCGANHALLMLEGSGDGSRGQLGVAAAWETSYVVDVVVAMGSDEFGALGSIAASFRHVFAHILLSWGAHRHGQRLGKEHTLILGLGS--DRKGQLWAGTFCVG-DNARGQLLACGSEHVLALVWGWGWNEHGNLGGR--VVWGGCGTSWIAV Copci SAGSNAQGQLGHSENEDEIAAGANHTLALLEACGDGRRGQLGIAAGWETSYVVDICFSFGSNDFGDLGSLVASQHHVAAILVVGWGASRHGQVVGSQHTVVLGFGS--NRKGQLWNGTFGLG-SDTHGQLLSCGTEHVLSLVWGWGWNEHGNLGTV--VIWTGSGTSWILC Croqu1 AAGSNSNGQLGLGHTDDSFAAGGRHSLILIEGSGDRSNHQLPVGSSWETSFVVSVVLTFGSTDFGLRGNLIAGPKHVVAVVLMGWGAARQGQLVGKEHTVILSLGS--HKYAQ-WNTTFLLG-NNSQAQLLAVGSEHVLV-VYGWGWNEHGNLGQK--LVFAGCATSFLCV CryneH991 SCGSNAGSHLAINHPNDQVISASAHSLLLLTGAGTNTFGQLGVAATWTTSFVVQVIVSCGSNDFGELGMIKGGQRHVLVVVIMGWGASRKGELLGASHTLALGWGS--NLKGQIWGGSYFLG-SNTHSQLIVAGTEHLLVLLFSGGWNEHGNLAGK--VLWGGCASTWVWV Crypa2 ALGSNGSGQLGIDHDQDQVAAGGNHTLLLSECAGDFSTGACGIAATWESSVIVTVVSTFGAGQKGELGGLSACMGHVVALLVWGWGNGRKGQLCGREFTALFVLGS--DKAGVKWGGVYILG-KDDHGQLIAIGSEHVVAVVLSWGWGEHGNCGSE--IVGAGCATSWVSI Debha1 ACGSNGSYQLGISNDEDKISSGGNHTFILTNSAGDNTYGQCAVSCGWEFSILMDEIYVCGIGMKGELGDLKSSINHTIIKLLYGWGNCRKGQLLGRDCTVILIYGKGA--ETYDWSSNHYLG-NNSHGQLYEIGSEHGLVLVYAWGWGEHGNCGDR--VLGAGCATSWLCL Dekbr2 ACGSNGGYQLGVGNSKDAMSFGGNHSLALLEGSGSNSEGQLFIACGWEFSVAEGEIIVCGYGPNGELGQLCTSIHSVIVVFVYGWGNNKRGQLMGRDFTVFMPIFRGKDNFNIEWTSVQILG-SNTKCQHAAVGSEHGVCTAYAWGWGEHGNCGNNEKIVFAGCATSFVEV Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel AWGANSHGQLGLGFESELIRGGGGHVLILDTACGWNNRGQLGISCGWDISGAIKRLFVWGSNAFQQLGRISFGLRHCAVLTIYVFGRLRIMDPSGQNHMVLKTLGD--NKFGQSWTHNAAVG-RNCYGQLIHMGAEHGLLRVYTWGWNEHGNCG---------NSFTTATS Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 SAGSNSLGQLASAGSNDSIAQCANHSLLLLRGSGDGRKGQLGIAASWESSFVVDILLSSGGDDFGDLGDLKAGLHNVIVKLLVGWGAARQGQLVGNQHAVFVPLGS--NRKGQLWNGTYLLG-SNSHGQLITCGSEHVLVAVFAWGWNEHGNLGGK--VVWAGCATSWVVI Fusgr1 ALGSNGSGQLGIGHKEDQVTAGGNHTLLFTNWSGDSTPGACGITATWEASIIVTQVFSFGAGLKGELGDLAACMGHVVAVLVYGWGNARKSQACGREFTCLFVLGS--DKWKIQWGNIFILG-RDDHGQLIAIGSEHVVALVLSWGWGEHGNCGST--IVGAGCATSWVFI Galma1 SAGSNAHGQLGNGSLDDGLACGGNHTLILLEGSGDGRRGQLGVAATWETSYVVDVIISLGSDDHGDLGSISSGQRHVIVHLLVGWGTSRHGQLLGIQHTVVFGLGS--DRKGQLWNGSYLVG-SNSHGQLIACGSEHVVALVWGWGWNEHGNLGAD--IIWAGCGTSWICC Ganpr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ACGSNGNGQLGIGSFEDVISGGGNHSAIITSMSGLNDDGQSGVTCGWNFSLAVGYIYSFGKGVYGELGKVVCGLRHVVCLNCFGWGSNKYGQLCGQNHTVVLTFGL--NKYGQLWNNTIIIG-RNDHGQCCACGSEHTLIICLSWGWNEHGNCGGN--IVGGGCGNSWIWV Hisca1 AFGSNGSGQLGIGHLDDQIAAGGNHTLVLFKAAGSNQNGRCAIFATWEASFFVGHLYVCGVGNKGELGSISSSVSHTAATLVYGWGISRKGQLCGREFTAVAIFGP--EKWDILWHGVYVHG-RNDRGQLLAIGSEHAVAMIVAFGWGEHGNCG-T--VVGAGCATSWIMT Klula1 CFGSNGNGQLGVGHDEDKVSCGGNHSLLLLEWCGDNSSGQCAIACGWEVTIVIGWVKTRGRGDKGELGRCYATFQHCVVVVIYGWGNNRKLQVLGKDFTCVLELPELISQLSHDWSSLHILG-RGSHGQFFVTGSEHGVVTVYCWGWGEHGNCGEK--VIFGGCATTWLVL Lacbi2 SSGSNAHGQLGNGSLEDNVASGANHTLLLLEGCGDGRAGQLGISASWETTYIVDILISLGADDFGDLGSITSGQHHVLVHMIVGWGTSRHGQILGIQHSVLLGMGS--NKKGQLWNGTYAIG-SDSHGQLLACGSEHVLTLVWGWGWNEHGNLGEV--IIWAGSGTSWISI Lenti61 AAGSNARGQLATGDTEDQIACGSNHTLALLRGCGDGSKGQLGIAVGWETSYVADVLFSMGANDFGNLGSLSAGPHHTVVRVLAGWGTSRHGQLLGNQHTVCLALGS--TRKEQLWNGTYALG-SNTHCQLLICGSEHVLCIVWGWGWNEHGNLGGD--IAWAGCGTSFLFV Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 SSGSNSHGQLGTGHTEDSFAAGARHSIFLIRGSGDRTNFQL-VGSSWETSFVNSVLVSFGSNDFGLRGNLVGGPKHVIAVVIIGWGAARHGQLVGKEHTVIASLGN--HKYSQ-WNTTFFLG-NNSQAQLLAVGSEHAMV-IYGWGWNEHAT------------------- Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr VCGWNSAGQLALNNIEPRVACGWDFTYFVVEVCGSNKYGQLGAAAGMRHGAVVGAVLTAGQGRHGQLG-VACGTQHT-VIAVWGCGANRHGQLAGWSHTTAISWGR--RDYGQL---------THDSADRIALGSEHALLLILAWGWNEHGNVGGQP-ILAGG-AHSI-VL Morel2 AFGSNGNGQLGIASDDDDFSAGGNHTALITHMTGSNKDGETLVACGWAFTIGLQVVYAWGSGSFGELGKVRAGLRHVLLLALMGWGSNRQGQLCGQNHSLVLSSGL--DKYGQLWNHNAAMG-RNDHGQLYSCGSEHTLAMCYAWGWNEHGNCGHR---VTGGYGSSWVWT Mucci2 AFGSNGSGQLGIGHVQD---GGGNHSAVLTKMAGLSQFGEE-VVCGWALTMAVGRLYGIGTSRWNEL-SVACGWRHSVALDVYGWGWGRHGQLCGHLHTLLRAFGS--DKYSQLWHHSALLG-RNDHGQLIACGSEHTLAIVLAWGWNEHGNCAAK--ALGAGCATSWIGL Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ALGSNGSGQLGIGHKEDKIVAGGNHTIILTTWSGDPNTGACGVAAAWEASIFTTRVYSCGTGLKGELGDLAACMGHVVAVLVWGWGNGRKGQICGKEFTCFLVLGS--DKWGIRWGNLFILG-RNDHGQLIAVGSEHALALVTAWGWGEHGNCGAK--IIGAGCATSWVAI Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 AFGSNGSGQLGIGHEEDTIAAGGNHTLLLTTAAGCNADGRCGVSATWEGTIAVDRVFVFGSSPKGELGALASGMAHSAAVLVYGWGAARKGQLCGREFTVVSVLGDRGNRWGILWHGVYVHG-RNDRGQLLAVGSEHALALVAAFGWGEHGNCGEK--VVGAGCATSWMIV Phybl2 AFGSNGNGQLGVGHRKD---GGGNHSAVLLQLSGLGQQGEA-VACGWSFTLLVGYVYGFGTAKYGELEKVDCGWRHAIALDVYGWGWGRHGQICGHIHTLLLGLGS--NKYGQVWHHSASLG-RNNHSQLVSCGSEHTLAIVLAWGWNEHRNCGA----IGTGCAASWILT Picst3 ACGSNGSYQLGTGNDTDKISCGGNHTLVLLQSCGENVYGQCGIACGWENSTLIGEIFVCGLGNKGELGEVKSSLNHTVIKLWIGWGNSRKGQLVGREFTAIGTFGKLQVETPLDWSSVHLLG-NNSHGQLFTVGSEHGLILVYSWGWGEHGNCGAR--IIWGGCATSWLVV Plicr1 AAGSNAHGQLANGTVDDNLATGANHTVVLLEGSGDGGRGQLGVAASWETTYIVDCIISMGADDFGDLGFIETGPHNVV--VVFGWGTSRHGQLVGSQHAVFLGMGS--PRKGQLWNTTYATG-SHSRGQLLACGSEHVLALVWGWGWNEHGNLGAR--AVWAGCGTSWIVT Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ASGSNSHGQLEEEEEEDSSSIGGRHSLFLINLCGDENQGQSGVTACWETSFVVDEILAFGSNDFDLRGRLHGGCQHVIAVILVGWGAARHGQLLGNQHSVLVCWGS--NRNGQIWNATFVIG-SNSHGQLLVAGSEHLLLTIWGWGWNEHGNLGSK--LLAAGCATSFVIV Punst1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 GFGSNGNGQLGLGHVED---GGGNHSAVVTEFAGFSQLGEN-VACGWASTLLLGKVYGVGSSRWNEIDSVSCGWRHAVALSVFGWGWGRHGQLCGHLYTIFRGVGS--NKYGQLWHHTLSLG-RKDHGQIFCCGSEHTLAILIGWGWNEHGNCATK--IFGAGCATSWFAV Rhoto1 CTGSNSHGQLAHG--DDQVACGANHTLAIAYAAGSNARGQLGVAACWETSFVVDVLISFGANDWGE--RLEAGPRHVVALCLLGWGASRHGQLFGRDHTAVLLLGA--NKHGQLWNSTFFVG-LNSHGQLLACGSEHVLALVYGWGWNEHGNLGGE--VVWAGNATSWIQI Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 AFGSNGQRQLGLGHDEDKIACGGNHSVMLTNGCGDNRRGELDVACGWDTTVIVGRVWQRGGGCY-EFT-VYGCFQNFVVVQVYGWGSNTKCQLMGKDFMVIVASGRLPTGFELKWTSIHLWG-RGTHSQLVATGSEHGILTVYCWGWGEHGNCGSG--KVFGGCATTWIVL Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 AAGSNARGQLGICSTDDSISGGANHTLALLEGAGDGSCGHLGMQAAWETSYAVDVLISMGGDDFGDLGWLTAGPHHVVLRLVVGWGACRHGQLAGHHHTVMLAFGS--DRKGQLWHGTYIVG-SNIHGQLLACGSEHIIARAWGWGWNEHGNLGSE--VIWAGLATI---- Schpo1 SLGSNGNFQLGLNNDEDKISCGGNHTLLLDEACGDNRKGQCGLTCGWEFSVIVRRVCSCGEGLSGELGDISAGLRHWICVTLYGCGDGRKGQLCGVQFSAVLVLGG--EKWNVAWSTLSLLG-RCDRAQKIASGTEHNILRVLIYGWNEHGNA-AY--IVAAGYATSWIVI Sorma ALGSNGSGQLGIGHKEDKIAAGGNHTIMLTSWSGDPNTGACGVAATWEASIFTTRVYSCGTGQKGELGDLAACMGHVVAVLVWGWGNGRKGQICGKEFTCFLVAGS--DKWGIKWGNLFVLG-RNDHGQLIAVGSEHVLALVTAWGWGEHGNCGAK--IIGAGCATSWVGI Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 AFGSNAHGQLGTGATDD-LAGGANHSVIVTAAAGANDRGQLGVACGWDHTLALGDLYVFGSNEFGQLGKIAAGMRYSLILTVWGWGANKYGELCGQHHSILLGLGR--NRHAQLWSFTGIRG-RNDHNQLVACGSEHGIAICMAWGWNEHGNCGGV--TVGCGYGHSLIYV Sporo1 ------------------------------------------VKA-----------------------RLAAGPRHILARILVGWGASRHGQLCGKDHSAILSLGS--NKHGQLWNSTFVVG-SDSHVQLLSTGSEHVLAILFSWGWNEHGNLGGK--IVWGGMATSWVLM Stehi1 AAGSNGQGQLANGTRDDSIANGGNHTLVLLSGSGDGSKGQLGVGASWETSFVVDILISLGGNDFGDLGDLATGPHNIILHVIIGWGKSRHGQLLGHQHSVFLGLGS--DQKGQLWNGTYVLG-SSTKGQLLAYGSEHLLVLVWGWGWNEHGNLGGR--AVWAGCGTSWIAV Tapde11 SLGSNGNHQLSLGHNEDTLTSGGNHTLLLTDATGSNEHGQLGVACGFDFSVLVGGIFVAGLNDKGALGHLAASINHVVMVLVYGWGNGRQGALVGKDWTIVLGMQG--RR----WSTVHFLG-RDDRGQFLASGSEHSIGIVYVWGWNEHGNCG-----VAGGYGTTFIW- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LARLTISSYSASTHSDR----QSHHTL----GAGTNTLGQLGIAVTWSSSFVVEILIACGSNDFGELGFIKGGQRHVICVIVIGWGASRKGELLGASHTLVLAWGN--DTKSQIWTGSYILG-SDTHSQLIVAGSEHLLMDLWTGGWNEHGNLGGK--VMWAGCANSWILV Trire2 AIGSNGSGQLGITHKEDKVAAGGNHTLLLTEWSGDPASGACGVAATWEASIVVTKVFAFGIGQKGELGDLSACMGHVVAVLVYGWGNCRKSQICAKEATCIFVLGS--DKWGLVWGNFYILG-RDDHGQLIAIGSEHVVALVLSWGWGEHGNCGSK--IIGAGCATSWICI Umbra1 CFGSNGNGQLGIGHDID---AGGNHSALLTTFCGDNSQGQC-VACGWSFTILVGQAYSLGAGNRGELGTIACGYRHVVALSAMGWGSNSSGQLCGQTHSVFLTLGL--NKYGQLWHNTVVLG-RNDHGQLMICGSEHVLCIVYAWGWNEHGNCANP---VAAGCATSWVIA Ustma22 VAGSNSGYQLGVDHNEDDISSGANHTLALLQVAGTGTHGQLGVVCGWNCSYVVDVLLSIGENTFGELGDVAAGLRHAVAALVAGWGSARHGQVAGRDHTVVLCIGS--NRQGQLWNSTHLLG-SNSQGQLLASGSEHSILLVWGWGWNEHGNLACT--PVWAGCGTSFVLV Walse1 AAGSNSNSQLAIPG-EDRLSTGGNHTLAIMKGAGLNDSGQLGCSASWSTSFVLSFLVSFGSDEFGIRGDISSTFRHAVVLLVYGWGASRKGQLTGREHTIIQCWGS--NQYGQLWRGTVVYG-RS--GALMVVGSEHTLILVWAFGWNEHGNLGIT--AVFAGNATSFIIT Zygro1 ---------------------------MEVE-------------------------------------KLFSSFQNCVVVEVLGWGSNTKCQIMGKDFMLIIAIGSLPREFRLQWSSLHIHG-NGNHGQLFTTGSEHGILIVFCWGWGEHGNCGSNA-TIYGGYASTWIIC [Cluster3147.fasta_al_trimmed; alignment length = 201] Allma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 SDTL--------PNPSAEGPLKKK---------KKRNFKYFVQKAKRKELTAVELGDLSV-PDSAFLDTSSFEPRSLDQLPAF--LKSKASEGTPHTLVVCPAALRAADVVVGKLFAKHIKLEEAKQFLQRARIGLGVGTPARILDLIDAGSLKLDELERIVIDGSYIDQKQRGIFDMKETHIPLLQ-LLTRSEFIQVLVF Aurde31 ADDLADDYIADVSDNEAAKKRKRREQDKQKKATKRRKFATLASVQAKKDASAIELEELAI-PETCIEDTSSFTERSLENLCQF----GQKSKGAPTLIFVTSAAMRGADVIVAKLFAKHLKVEDQVAYLRRTKVVAAVGTPGRLGKLLEENCLSLDALSHVMIDFTHRDLKSRSVVDIPETRQELFKTVLGNERLVKLVLF Batde5 ADSKPS-----RSQRRSSKKRKRMS------SPNTIKVASLQSKRSR--------------------------PRTLAQSAPY--LDAKLQQPSLRLIIVCSSAERTLEIIILKLFARHIKLEEQVGLANSKMFPIGVGTPHRIAKLLMEDQPGLSKLMHVVFDQSCMDSKKLQLFDSADKE--LAE-ILA----V----- Botbo1 GDDLEDDLLLDDSDVEAEKKRKRRAKDKERRE-KKRRLTFLARGQQKDKLSEMELDDLRI-PESSIADTTAWTARTHETLPDF----AQTPKGAPTAIVLAGNALRVADLTVTKLFARHFKLAEHIQHLKATKVGVAIGTPARVGKLLAEPALLLNALTHIILDVSFIDAKQRSMMDIPETRDELFKGVLGHERIVKLVLF Botci1 SSKIE---LQDVPTTR-QEGPKEKINE----VAKRKKHSYVASQTRRSDLSSVELEDRYI-PVAAVQDTTSWTPRSLDNLPEF--LEWSASKGSPHTIIVTAAGLRAADLAVAKLFAKHIKLKDSIGFLKSSRTGIAVGTPQRLKDLMDEGSLAVDRLERIVIDASHIDQKKRGILEMKETQVPLTT-WLGQKLFLQVLFY Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ADDLDDDYLLEQADDEAEQSRKKPRRARRKRQNLKQKAKFMSELGNANKLSGLELEEAQV-DSTHFVDYESFKPHTLANMCSF--VKAKVP-GAPRALILVPSALRAAEVIIGKLFAKHFKVDEQIEYLTKNHMRLAVGTPNRVSKLVEQGSLNFSQLEYVIVD-CERNSKNQSIFQLDGVNKDLFD-FIR-SDCVKLALF Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---------------------------------------YLKLHFSK--LSKLEFEDISL-------TESNFT---IDTTTSY--FKSTAHSMSPLIIVVCGNALRASKFNSIKLFARHMKIDDQIKLLRENVIHFAVGTPERIRSLILQDALSLEHTRAFVIDWNWRDVKLKRLIDIREARASLLK-----DCVVKIGLF CocheC53 SDS---------GQEGKKAKRKEK---------KKQRAKYVNARTRLQELSSVELADKFI-SARTVQDSTSWSPRTTDNLSAF--LKPTPSKGAPHTIVVTLSGIRAADVCVAKLFAKHLKLADQVAQLKKSKVDYGVGTPDRLVALLEDGALSTANLKRVVVDVSYIDQKKRGILDMKELHEALMK-LLLRKELL-FLFY Coere1 ADDLQDDLDENYNDKDKKKRKKKNSKS------------LWNKYMAKPSLGELELGDISL--PTHM-----YSKEPTQKSTTY--LEVKGKNGAPQLLVLCSSALRVLELVTLKLFSRHIKIDEHKELLKYTAVDIAVGTPNRVRKLMEEGNLKVNRLKLVVID-CWQDDKMRVIVDMDDTRNDIWRDILLP---PDYSFK Conco1 GDALEDDFHLSESENEAKKANNK----KEPKPPKKVKLDHFNTCFKVKTLSDEEFENTQF-KDTYF-KLSDYKPHIMENLAPF--VKSDLPKGHPTVLMITSSAIRATDLIVAKLFSKHIKLSEQVQFLKENTFNIGVGTPNRILKLSETKDLKLGRLKYVILD-MHRDVRKLNIADMRDTAPDLFT-FYK-DFLTKLILF Conpu1 GDDLEDDFVPDLSGEDKEKKRKRRAKEKERKL-KKRKVAYMSSLQAKPSLSTMELDDIRI-PETSIVDTTQWTSRSLDKLPDF----SQRSKGSPTLLFICGAALRVADAVVAKLFAKHFKLEDHVSYLKRTKIGSAAGTPGRVGKLLCDTALSLSQLTHIILDASFRDAKERSLLDNPETRDEVMRTILGAPKVIQLVLF Copci GDDLEDDFVVDLSEEEASKKRKRREKEKER---KKRKLAYLASMQKRKDMSDLELEDLRI-PASAIADTSMWTPRTLDHLVDF----SQRPKGSPTLLFLTSAALRVADVSVAKLFAKHIKLAEHVTYLRRTRVAAAPGTPGRIGKLLCETSISVSQLTHIILDITFRDSKNRNLLDIPETRDEVFKTVLGAPKVVQVVLL Croqu1 ADALDDQFQLNGSDISTSKDVSQPQKKLAK-KPKKDSTKYLTDRQKRSKLSDLELEPLRF-HQSWLLDVS---KSQRANLGSW--L-KTPTTGSPAILVIASAALRAVDLCVAKLFARHFKLQEHITHLNSALVAIGVGTPNRISKLIESKALKLDRLRWLLLDTTWLDAKSYSLPDLPEAAVRLWQGILGNSDLMKLVLF CryneH991 GDDLDDGLELDSSDIEAEKKRRKKEKEKER---KAKR-RVLLHSIREPSSSAIEIEEVLI-PPANLLEPPTYPPKVD----------KKEPKGAPAVIVLGLSGLRCADIVVAKLFAKHFKLADQIKYLERTKVSIAVGTPARVGKLLA--------------------EETRTILTLPEVRDELWKSVFSGAARVKIGAF Crypa2 SKPT---------TQKKVARPKQK---------KNRRPDYVAANTKRTELSAIELSDLYV-PAGAVRDTTAFSTRVKENLAEF--LEGTAPKGSPHTIVVAGAGLRAADLVVAKLFAKHFKVAEQVDFLKKNRTGIAVGTPARLAALLEDGALSIEHLKRIVIDASHIDQKKRGIMDMKDTMMPLAQ-WLTRKEFLDLLFF Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ADSLDVNFVLS-SDSEKPARAAKPAAKKGQPPAKRLRFDRLKAELQQ-QFTDMELGGLSL--ASQIADTSASFPREDANLVQF--IKSKHKSALPRVVIVCSSGQRCVDVIIAKLFSKHFKVSEQVDFLNKNDSRICVGTPNRLEKLASEGALDFSRVQVVIFD-MKVDATGRSIFEIAEVRKDFFRTTLSKNLIAKLALF Fomme1 ---------------------------------MKEKAIYLAKLQAKPKLSTVELDDRRI-PENALVDTSAWSPRSLDQLPDF----AQKSKGAPTLLFLTGAALRVVDAVVAKLFARHFKLEEHVAYLKRAKIGSAVGTPGRIGKLLCDTALSTSALTHIILDVTYKDAKQRSMFDIPETRDEVFRTVLGADSVIQIVLF Fusgr1 ST--------------TQPKPKKS---------KKRKAGHLAQKLTRSDLSAIEISDMTL-SANTIQDTTTWQPRTLDKFPNF--LEYKSAKGSPHTLIVTGAGLRAADIVIAKLFAKHFKIEEQVKFLGEHRTGISVGTPARLMDLMDNGALSLDGLKRLVVDASHIDQKKRGVLDMKDTMMPLAR-FLSRKEFLALLFY Galma1 GDDLDDDFVLDFSGDE--KKRKRREKVKERKA-KKRKLAYLVSMQVKPNLSALELDDLRI-PESAIAQTTIWTPRSLDQLVDF----SQRSKGAPTLLYIAGAALRVADVTVAKLFAKHFKLAQHVTYLKRTKIGAAVGTPGRLGKLLNETALNVSALSHIILDITYKDAKNRNLLEIPETRDEIFQTVLNNEHVVQVVLF Ganpr1 ADDLDDDTFVD-----ADAKPKKA-VKKSKKKPQDGKTE-----------------EVQI-P-SELTVPKSYDPRDSSDVIHF--LGLKSKRTDPIWIVAVMSAERLTK--AAKLFGRHMKMPEQVEFLAGRKVSVAVGTPNRLVKLMEIS--TLRKAQVLVLDGTYHDKKQRTISTLNETKDD----IRSLTSLMKIAIY Gloin1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 ---------------MDEGGIKKR---------KRKR--FFAQQAKRSQLTAIELDDVYV-PEQAFLDTTSWKPRVLENLPAF--LKSTAPKGSPHTIVITLAGLRAADITVAKLFAKHIKLAEAKEFVKKTRVGIGIGTPVRLNDLATSGELRLKQLQRIVIDGSYVDQKKRGIFDMKDLHLPLLQ-FLNRADLVEILIF Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 GDDLEDDFVPDLSEDEAGKKRKRREREKEKKA-KKRRLAYMSSMQRKPTLSELEIGDVAI-PAPSITDTTSWTPRTLDHLVKF----SQKSKGSPTLLFIAGAALRVADITVAKLFSKHIKLADHVTYLKQTKVGAAVGTPGRIGKLLCETALTISALSHIILDTSFRDAKNRTLFDIPETRDEVFKTVLGGPEVVQVVFF Lenti61 GDDLDDDFVPDLSDEEKEKKRKRRAKEKERKL-KKRKLAYISSMQAKSKMSGIELADMQI-PETSIADTTMWTSRNLDQLVDF----GQRSKGAPTLLFVAGAALRVADVTVAKLFAKHIKIEEHVGYLKRTKIAAAVGTPGRLGKLLCDTALSTSALTHIILDVSFRDVKKRSLLDIPETRDEVFRTVLGAPKVIQLVLL Malgl1 ---------------------------------------------------------------------------------------HPCRAGMPYVLVLAGNAQRAADIAVAKLFARHFKVEEQDAWLRAQPAPLGVGTPHRVHTLIQQGSCRLDHLAALIIDFSWTDAKQRTVFDTPETRGAMLH-LLSDKHVCRLALF Mellp23 ADALDDQFLLNESDNSDETNRSKPTKQKSKAEPKP----YLTDRQKRPKLSDLELQTLAF-RESWLLNVS---KPHRGQLGSW--L-KIETTGSPILLVIASAALRVVDLCVAKLFARHFKLSEHITYLNTTPVVIGAGTPDRISKLIEAKALKLERLRWIMLDTTWLDTKSYSLADLPEKAVRVWQGILGNPEITKLVLF Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr AEALNDDWWDGMDEAALAKRAKRKE--------RKKRAAYLQSFLKS---SGFDL------PREDDVRHVDWDGRTLDQLGNFA-LRSRKRR-HPRLIVVTFAAKRVVDLIVAKCFGKHMKLDAQVDFLQKKEVQIAVGTPQRLCELFERECLSFRNKEVLLIEATTKNSKGRTIFEEVESKAALAQ--LIANHVGKIVCF Morel2 GDALEDDFQASLSDGQAPEAPKK------KKQNKSKKA-ALNDSQDREHLSSIERDERRI-PGSAIKDVSPFADHTLVHLESF--LKKKKPLGAPVVLIVSASGIRAVDVIIGKLFAKHLKVAEQVYFLENTCTHICVGTPNRIDKLISDGVLDLSRLELVLID-AHTDAKKRTILDIQEIRVDLFR-MLGLEALTKLAFF Mucci2 ADDFEDDFVEEYSDNEAEEPQKK----KKKKQPKKKRG-YLQDRQKLPKLSAVELEEQTL-PESQLVNNDNFKEHTLEALPNY--VKAKKP-ASPVALIVTHSAIRAVDLCIAKLFAKHFKIEDQIWFLEHESIHMGVGTPNRLQALVEQGHLKLDNLELLVID-TERNPKKFNIFDLQEVRTDLFQ-FLG-KHITKIGLF Mydma ADDLGDDWWENEDE-KKEAKKKKSNVPLAKKKQKKKKLSYFEKELGK-TLSCIELEDIKP-------NHDSWVPKVIDQLSSY--LKCKKVQGSPVMLIITSGGQRAADLLSMKLFAKHFKINEQADFLNKNVIHLGVGTPNRVAKLIELGNLSIKYLSYIVIDWTWKDDKNRSIWNMHGVKDDLFQ-----KYITYVGLF Neucr2 ATEM-------------EGGAKKK---------KRSKKAHIAQKVTRTDLSSVELSDLYI-SANAIKDTTSFQPRNKDNLPDF--LESEAPKGSPHTLVVAGAGLRAADLVVAKLFAKHFKVEEQVSFLKKSRTGIAVGTPQRLIDLIENESLSLDSLKRIVVDASHIDQKKRGIADMRETMMPLIK-LLTRKELVDLIFY Orpsp11 ---------------------------------------------------------------ECFVNSSFTSQRTLSNISSF--IKGKPPKGQPSVLVVTQSAIRAVEVIVGKLFSKHMKVKEQVEYLQKSVVKIAVGTPNRLIKLAEN--------------------------------------------------- Pench1 ADT---------NAPKAEGSSKKK---------QKKN-KHFAQKAKRKELSAVELSDLSV-PDSAFLDTSSFTARKLEQLPEF--LKSKSSEGTPHTLVISGAALRAADVVVGKLFAKHIKLEEAKQFLQRARSGIGAGTPTRISDLIESGTLNLEELERIVIDGSHVDQKQRGIFDMKDTHIPLLK-LLTRPELVKILVF Phybl2 -----------------------------------------------PDLTAVELEEKEL-PEKSFVDNQKFKEHTLEALPNY--IKSKKP-ASPVALVLTHSAVRAVDLVIAKLFAKHLKVEEQVIFLEKYPIHIGVGTPNRINTLLEQGHLKLDRLELVIVD-TERNAKRFNILDNDAVRGDIFS-FLG-NYITKLGLF Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ---------------------------------QKRKLVYLSSKQAKSKMTAIELEDMQI-PEMSIADTTMWTPRTLDQLGNF----SQKSKGAPTLIFIASAALRVADVTVAKLFAKHFKLEEHVAYMKRTKVGTAVGTPGRIGKLLCDTAISLSALTHIMLDVTFRDTKKRSLLDIPETRDEVFKQILGAPKIIQIVLF Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ADALEDQFSIN--DDGAIAELKRRKKEKAKTKQKLRKEKYLKDRQKRPLLSDLEFESLPL-EKSWLVDVS---KPLRGHLGAW--L-KETPDGAPVALVISSSALRAVDLCITKLFAKHFKLPEHVSHLKETKVSIGVGTPDRISKLLTYKGLKLDRLKFLILDLTWLDAKGFNLTELPDSAHKLWKSLLGLPKTTKIVLF Punst1 GDELVDDFVPDLSGDEEEKKRKRSAKEKERKA-KKRKLKYIAAAQAKSEMSELELEDLRV-PESAIADTTAWTPRTLDQLPEF----AQKPKGAPTLLFLSGAALRVADATVAKLFAKHIRFEEHVSYLKRASVAAAAGTPGRVGKLLMESALSVTALTHIILDVTHTDLKKRSLLSIPETRDEVFKTVLGAPEVIQVVLF Rhior3 ADDFEDDFQEEYSDNEEEQQPKK----KKKKQQKKKKG-YVKDRQMIPDLSAVELEEQYL-PEEIFVNNEKFNEHTLEALPNY--IKLKKP-ASPVALVVTHSAIRAVDLAIAKLFAKHFKIEEQVNFLEREPIHIGVCTPNRLQALVDQDHLSLSKLELIVID-TEKNSKTFNIFDNQEVRGDLFK-FLG-SHIIKVGLF Rhoto1 GDDLEDNFFIEASDGEKQPKSKRAAK-KA-KEKKTKKLARLAEKQKRPNLTALEMDEMRI-SQSMILDTSSVT--ARDSLRAF----AKMPKGSPRIIVLAGAALRVADLVVAKLFAKHFKLAEHAEYLKKTHVGLAVGTPNRIEKLLNETSLHLTHLSHLILDVSHLDSKKRSLVDLPEARADLFK-LLGSKPIMKIVLF Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro SDD---EMWWESSENEKSAQAKRRAKKADKFAQKQRELRVITKDMSK-TMTDLELEQVQL--AEHIVHADV--SRSKGQLTAF--CKPHPKKDPPTLIVISVSAKRCVEVKVLKLFAKHMKQSEQEKRLQR-----------------------------------------------------SWQ--------A----- Schco3 ---------------------------------------YLATAQSKKDMSAIELEDMRI-PEAAIVDTTIWTPRTLDNLVDF----GQKSKGAPTMIYIAGAALRVADVTVAKLFAKHFKLQDHVQYLKRTAIGAAVGTPGRVGKLLCETALATTALSHIVLDITFRDAKKRNILDIPETRDELFRTILGCPKVIQVVLF Schpo1 ADALDDDYQVDVSD--REKRKKQRQKQKER---KRAKLLLLNNYIKSSDLTDVELSDKVI--ASYIEDTISFSPKTVDNYPEY--IQVQNSN--PEILVLCISALRAIDVLVAKLFGKHIRLEEHINYCKANKIGVGIGTTPRIAQLTNE-CFTCENLKYIILDYSFRDIKNNSILTSKESRKA---DFLTSKTITKICFY Sorma ATEM-------------EGGAKKK---------KRSKKAHIAQKVTRTDLSSVELSDLYI-SANAIKDTTSFQPRNKDNLPEF--LEAEAPKGSPHTLVVAGAGLRAADLVVAKLFAKHFKVEEQVSFLKKSRREL----PSRLIDLIENESLSLDSLKRIVVDASHIDQKKRGVVDMRETMMPLIK-LLTRKELVDLIFY Sphar GDDLDDGLMYDVSDDDTAKGTKG--ANKQKKWKEKEAA-VWTEFVNENKMTEIELEEVTFNPVACFVDPSDAHDRNLKMLRPF--MKGPQKAGAPNVIIVTHTAMGAADIYVAKLFAKHIKVEEQIKYLQEHAVRIAVGTPNRISKLIEEGVLNLSNLTYVIVD-SRKDIKNQNIFNVKQIKSDFLG-ELCPNHITKMMLF Spipu1 ADTLEGDELLDAADFVAEKPKKK---VKTKKQGHGVDA-ALFAKEGLHDCSGWQLKGD-------------------DNISLF--IRSKSS-GAPKVLVLASSAIRAVEVCVAKLFAKHMKLKDQVEVLKKDTFPIAVGTPNRIQKLISDGALRLDELDFVIADGTHKDQKERTLFDVPEVRTDFFQ-LLH----VRFCIY Sporo1 ----------------QAPASKKAKKDKAKKEKKKAKLERLSEKQKKPTLSGLELDEMRL-NQSMIQDTSSVT--TREDLLAF----GKLPKGSPRIIVLSGAALRVADLCVGKLFAKHFKLNEHAEYLEKTFVGIAVGTPNRIEKLLNETSLKLTHLSHLILDTTHLDAKKRSLMDLPDARGDLFK-LLGCSKIMKLVLF Stehi1 GDDLEDDFVPDLSDDGAEKKRKRREKEKERKL-KKRKLAYLASMQAKPKMSALELQDRQI-PGRELNS-----YDLMEGIEDFGRLGSQRTKGSPTLLVLTSAALRTADMTVAKLFAKHFKLDEHVRYLSKTKVGAAVGTPGRVGKLLCETSLKTTALTHIILDTTHIDTKKRSLLDIPETRDEVFRTVLGAPSVISVVLF Tapde11 ANKRQKDALDD-SDSATEERRKKR---------KLHRASTVARLVRETDLSSIELSDATP-PTSSFLDTTAFAPRTLETVLAF--MEAVANKGRPHTLLLAASAIRVADLCVAKLFGKE-KRETQTAWLRQNRVNVAVGLPGRTHALLGHAALALDRVEQVYLDASYRDAKKRGMLGIKEVARDLVK-LLNAEVLI-ILF- Thetr FEPLELDFDDSGSDDDDERAAKKKKKEKKKKTKKGRKRHYLQRRLLSPEMSSVELDAVAV-PEAML-------PAASEQLGRF--TRAPRPQGAPRILIVTAGGMRCADVVPAKLFAKHFKVAQQAKFLQTHEVNIGVGTPNRLIKLIEASGLSLDRLEFVLLD-IQRDAKERSLLDMHGVDVDLAKHLLP----LHIGLC Treme1 GDDLDDQFELDSSEAEKEKRKRKREKDKIR---RAKRIHLFTSSLKAPQASELELTDLYL-PSKDLSNPPT--KKQDDSKGRI-------PTGSPNIIILCLSGLRCVDVVVAKLFAKHMKFSAQEEYLKKTKVSVAVGTPARVGKLIESGALRLSEGSVILLDLGHEDSKKRTLITLPEVRDELWKTFFNGKCRAKIGAF Trire2 SN----------------APAKKA---------KKRKAKYHAQKLARTDLSPVELSDLAL-SASSITDTTSWQTRSLEKLPEF--LESRPQKGMPHTIIVAGAGLRAADLTVAKLFAKHMKVEEQVALLQNKKIGIGVGTPARLMELIDNGSLKLDKLQRLVVDASHIDQKKRGVMDMKDTMMPLAR-FLARKEFLALLFY Umbra1 ADALEDDYLVEEGDTQAEEPTKK----KKKRKPKKN---YILDRQKRSTWSAIEHDEQAP-AISAFLDSQKFTPHTIEFLPSF--VKLKEPPAAPAIIIITHSAIRATDLVIAKLFAKHLKVEDQARFLAESRLHFAVGTPHRVKELIELGHLKLDRLELLVVD-TEKNAKRLDIFENDAVNGPLFD-LFG-THITKLGIF Ustma22 VDTLEQNYVLDGSDDGEDKKRKRKEKEKAR---KQKRAAYLATKQSAAKLSELELEELRL-REAMLLDTTPFDPRTLETLADF----HPSVSGRPALIMLTGNAQRAADLAVAKLFARHFKLKEHEAWLREHTTPLAAGTPQRVAALIASGSLQLDSLQAIVIDQTWVDAKQRNVFDSFETRDELIK-LLALDAVAKLVLF Walse1 GDDLNDDYNFD-SDNDTGKKRERDDAEPQQQTQQKKKKSFLVDQLKSSKLSDIELEEKLI-PESAIEATTSYSSRSKDTIVDF----SKQNKGSPRLLVICPSAIRCTDIVIAKLFAKHIKLHEQKEFLQSNQTVIAVATPNRAKSLIEDGAFSTKYLGLILLDTSYVDDKQRTLFDVPEIKQQLFD-FLGLKSITALCLF Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3148.fasta_al_trimmed; alignment length = 291] Allma1 --------RRLAAAVLATALATTSAAFDEAIKVLQA-------------------------PATKDL-------------------TVWAFRYADFSKPEFRQLGLDHFVKIQFAEQRGVFQDFREDEINVEVHL-LIKMGSDLAPLETTTPPAVYIQPFHEEKKYTFVLLDADKVRPDLEMQS--EEILWMVKDIPLSASTALVLPYVPPHPTKGSGTHRVVALVLEQPAES-ADAAPRQVAVWDLVQAQGLTPRGLLLWKTEWDTTVSDVFRN--LKEREPRFVKYQNV Ashgo11 -SFHSSRTLGVQSKAVKKPPSLKKRMFKMAYEYLQLRAQQKYDA--------------QAS------AARK--VQLEVEAELHNPEVKYNFQFHDYTQPVYRHLGRKHWESMQRLETLAVIPDTLEPRADVQIKFKWVEPGEVVSTNVTSMEPAIKIQEFDEQQLYTILIVNPDV--PDLEANTYSTSLCFGLQNIKIAYNDNVLASYLPPVPEKNAGTQRFAVWVFRQP-P--LP--REHFDIRAFTALHGLDAVGAHVWRSAWDSNTAAVRELYR-------------- Aspfu1 -ASRPLIQRTFQSTALARPALVTSPCFQEARKVLLADREEKIKKITAMREKIARLQAIPTEVQKSKLAMELELERLKILADINDPIVKKKFEDGDMTKPIYRFLADRKWREVQRITQMKVIPDVCDPVVDTKLYF--IQPGEFVNSRVSSTPPKLNIQLFEGEKLVTIAVVDPDV--PNVEKDGFDYKMHYLAVNVPISATSTVVLPWLPPVAQKGSPYHRLSIFIMEQKDAP-LN-FRD-VLLRTLQTRYHLKAIGAHLFRTQWDENMLEVMREIGVELRRKRVE---TF Aurde31 ------PRSSKVPRLPS-FASVEKPVYDRALEIIEADAVKLQEEVRQLREKLND-------AAER--KIQDKINIIEIQSTINLPRPRWEVKHGDFSLPVHRHLVEEKWRKMERVYQMGVVPDLFHPNVDLRVEFAEMEPGRYLLPNQTLAPPRLRARAFHDERLYTLVMVDPDV--PDVERATFQSFAHWIVPNVPLSI-HT--LPYVPPHPQEGTPYHRYTIFLLRQRKVA-MD-LRLGFDLRQFSAQHGLVGGGVFMWREVWTEDVSKIYRD--LKAREPKYAKYY-- Batde5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 PRSFTAARTRLSTDAVA--------AYDLAVELINGDAAAKRAKVERLH------------KTGEDVKLEKALEKLEIESEINLPEVRWNFKNGDLSKPVHRHMLERSWRNMERVYQMHVVPDILHPTLDLRVNFEDVEPGVFLGPEQTSKPPTLKAQVYHDTRLYTLLMVDPDV--PSPATKSFHTYVHCLMPNIPLSVLET-ALQYVPPHPQQGTPYHRYTLLLLPQTSAP-LA-LREAFDVRAFVKEHKLPGGGIFFWRGVWDESVSKIYQE--LALPEPKYGKYI-- Botci1 -AVGPMARRTFTSSTTFNPATVVRPCFQEARKVLQADREEKLEMIAKERLRLKNLEAQDASQKQTRISIKRYLEYLKIQADINDPLIKKRFEDGDMNKPIYRYLADRKWREVQRLEQFSIVPDLFEPTAEVRLAF--VQPGDYVDSRVSEFPARLKVQVFDGERLVSVVVVDADV--PNVENDHFNTRCHYLAANIPISPVQDLILPWLPPFAQKGSPYHRYSIFVLEQKPQV-LD-VRDRFNLRGFKDRHDVQPIGLGLFRSEWDEGTKGVMQRAGMEFKRTRIPKYKSL Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -TISRQFQLRIQNENIRKPASIKNSTFSEAYKILEADASKKYGRLEKLQEEYTKIEDKSST------SIKREIEELQIETELRNPEVLYNIEYNDKSQPIYRKLLKEKWKEMQRLEQLHVIPDTLVPEADVKVKFDWIAPGSILPTFAVEKPPVVQVQEFDNERLYTVLLVNPDT--PDLEKNSFSTTLHYALANVSLNNIDNVLKDYLPLTPEKNTPAQRACLWVFRQK-E--LQ--RENFDIRSFVESNNLSPIGAHVWRQQFDRSVNEIREKYG-------------- Cangl -GFHSSVKLGINNVLVKKPVTIGRKAFAVSYKYLEDHASKLYEK--------------AKG------ELER--EKLIAKAESGNPEVLYNFQYHDYTQPVYRHLGRKHWESMQRLESLQVIPDTLVPKAEVNIRFKWVEPGEFLSSNVTSLPPAVKIQEYDSKQLYSVLIVNPDE--PDVENDTFKTTLAFGLVNIKIDYNDNVLAEYVPPVPEKNVPAQRYSVWVFRQT-P--IA--RDNFNIRDFASKNNMEAIGAHVWRSEWDLNVSKVREMYN-------------- Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -AAAAAARRTMASTAAATANTKTSPAFTHAQSLLAT-------------------------APHQQL-------------------TIRAFRHGNFALPEFRTLGLRHFITVQFAEQRHVFSDFHEDQINVEVHVVRIELGADVRPTQMMEPLKVCLQPYHEVKKYTFVLVDGDMARPDWEMRS--EQVLWMVKDIPLSAATALVVPYVPPHPTRGTGAHRILAFAFEQ-----SDSTPRGISLWELIQAHKLTPRGIHVWKAQWDASVSKVFTE--LNVKEPVFVRYEGI Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 -ASTPSVRRLLSTSAVAHPQMVENKCFQEARKFLLEDRQEKIKKIETQQLRIKNLMDQDPSAKEHRLSMRKHLNELIILADINDPVVKRKFEDGDMNKPIYRYLADKKWRQEQRVTQLAIIPDILDLAADIDLGF--VAPGDFVDSAISEKMPRLNVQMFTGEKLVTVVVVDADV--PVPETDSFTYRCHLIASNIPLSPNNTIALPWIAPWAHKGAPYHRLGIFVFEQNAQA-LD-VRIGFNLRSFTDSNKLHPITATLFRTKWDDSMAGVMERAGVEFKRKKVE----M Coere1 -TSRALVRGPV--------------AYDEALKVIETYSSQKASEAEVAAASLKKA------ADADEIRLEKEWFDLAVEAKINDGEVLWNADQGDLSQPVYRYLKERAWRGMQRILQMFVLPDMNTPEAQLNIVSGVIEPGAVVDPASVLKAPEIELVSFRDTRLHTLVLLDLDE--PCEEQQSFREQFHWIVSNLAFSK----LLPYIPPHPAHGSPIHRYVVVALEQSNDS-VE-VSRDMVMRDFIAEHELRIVGISFFRSAWNESVDEIYRD--LKQAPPRFGSYENY Conco1 --------ITGANQLKR--------TYDQALEYLTQHSNSKLAQAKKIDEQLKDAKLDQAA------DLQTLKETLLTEAYINLPETQHKFQTGNVTEPVYKYLKTQQWNTRQRVEQMFVSPDVLDSHIKLSVE-EFVECGKFIDAEKTIQAPALSVNTFHATKHYTLIMIDPDH--PNEATQTYQQKPHWIIKNIPLSLTQT-VLNYIPPHPANGTGTHRYSIILLEQANDK-TE-L-----LPQFIENNKLTVKGAYFFRSKWSQAVSSIYSD--LKIEEPFFGRYHNI Conpu1 ----S-RRATLQSANQS-RLSPQNPAFDEALKFLKADSAALKEQAKVLEARIEDMKKQ---AVRQ---LERELEELEVQSEINFPEVRWKVANGDMSRAVERRLVERRWLKMERIHQMSVVPDVLHPSVDLRLTYKHVEPGVYLTAEQTRDAPKVFTTVFHEERLYTLLMVDPDV--PDEANATFQNYVHWLQPNISLNA-TS---PYVPPHPPKGTRYHRYTTMLLPQ--SR-ID-VRLGFNVREFLQKYDLTGGGAHLFREVWSEGVSSIYKD--FGIAEPKYGRYV-- Copci -LLRT-VRATL--STGSETISNQNPAYDLALEVLRKDSLALKEEIAELKKAIESEEKRYQEALDLELKKRQKLHILQVQSEVNLPDVRWKVANADMNIPSHRHLVEQKWRKMERIYQMKVVPDVIRPSLDLHLA-KLVEPGVFLAPRLTVEPPRLYANVFHDTRLYTLMLVDPDV--PDESTASYTTYLHWLQPNVPLTA-TH---KYIPPHPQRGTPYHRYTVLLLPQPPKK-LD-IRLGFNVRQFCQTWGLTGGGLHMFREVWDEEVSKIYKD--LGQEEPRYGKYVS- Croqu1 -ATVTLHQSAGRLASAR-SRSSITPAYDEAVAFLKQDAEQLALKMKTIESRLTENPRD---------GLQKSIIKLEIESQINDVDVRARHKAGDMSKAVYRHLKEKAWREMETVHRLRVFPDIISPTVDLTAKF----VGSFLSAARSVRPPTIRVQAFHEQQLYTLLMIDPDV--PNPSKQSFTTYLHWLVPNIPISA-LEQSLAYVPPHPARGSSLHRYTLLLLKQ--AK-LESLRRGFSARQWVQSTKMEAAGVLSWQSKWREQITRIYET--LKCPEPVYGAYTPL CryneH991 MSSRVVYRRAFS-------ISRNAPAYDAAISYLADYQSRTLSKLNDFKSKLPETPSH---------EELQQLAKLEIEAYANDPAVRRTFKETQMGKRIMRWLGEENWKKMQRALQMNVVPDLIPPTAPLTITL---TPGTFQRPSSFVQPPKITHQIFHPTALHTLLVVDPDA--PHHETHSFQERVLYMKTDIPISVVDG-LLAWEPPAPEQGTPYHRYVFLVFRQPSSS-VTTTREGFNLRDFLSSQGLSLTGLSLFRAEWSEEINSVFREKRVSEGAPVYGRKEEI Crypa2 -AARPIALRLFSNSASR-PNTTTLPCFQEARKILAKDRAEKLEEIKRAHLRAKTIEATPVKFKNKRLSLQRHVEALKIQADINDPAVKRKWEDGDMSKPIYRYLNEQRWRDVQRVQQFHITPDVFDPKMDVQLSF--IRPGEIVDSLVSEAPPNVRVQVFDKQRLVSVVVMDSDV--PDAETDSFGRRLHFMAANIPVDCLTKLAVPWLPPFSQEGAPYHRLSVWILEQHEAE-LD-VRDGFSLRSFKSEQNVRPYGFNMFRTIWDEGTKAVMQRHGIVFRRQRVHKYRHL Debha1 -VSSRNVRLKLIDSKTYEPGSIAKPTFKLAYNVLEAESEDYYKQIESLKERLNKVQDQKET-------IKNHIDKLLIKAERQNPEVLYNIEYFDKNQPVYREFLKNKWESMQRLEQLCVIPDTLDPKVEVKVKFDWVTPGEILPSFAVSQPPTIEIQEFDTEQLYSVIVINPDT--PDLTTNSFKTTLQYGLCNVPLNNVDNTFKEYEPLLPEKNAQTQRACLWVFRQS-P--LS--SDKFDVREFTSENNLTAVGAHVWRQHFDRSVNDLRSKYG---------GLAN- Dekbr2 -S------LAIKSKKLQEPVSLKKGIYPLAYNALQEESAKTYQKIELIEKKIAEVGNDKAK------EQKR--ENLLVEAEKNNPEVVYRSMFADRTQPVYRRFLEEKWKGMQRLETLGVIPDTLNPEVDVNVVFRKIEPGTILSSNVTSRPPSFEIIEFKKNDLYTILVVDPDI--PDVENDTYKTELLWALKDVPASNDDPELVSYIPSVPEKNTGNHRISAWVFRQP-KK-LK--REGFDIRKFSADNNLKAVGAHVWRSAWDRNTKNVRRMYG-------------- Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VGSRPLASAFYASRADTYEPYVLDPAYDEARRFIYHHRKGLNQKADSLVPLIEAEEALVQKSKNMKLERQKILTHLERTCFFRDQRIRHSLFDLENNEEFFRKYGNKHLVSRHRRENTALVAAL---TTQLMVKF--VHFANMLDANETAEEPRIR---FIPPSHYTLAMVDLDA--PDAIQRAFRSRIHWLVKDIPVPVLDAVVVPYLAPHPERGSEVHRFAFLLFGQEADA-LQALGRLFDFPEFLTRAPGRVHGACLFKSEWSPTVTELFDE-GQEGTRPDYTSN--- Fomme1 ----A-HRASLTTNTAV-PISLTNPVYDEALKLIQEDSVSLKRDLKTLRARVTDLEKDTASAL------KEKANVLEIQSEINLPWVRWYAANGDLTKPVYRRLVEHKWRNMERIHQMHVVPDLVHPSIDLRVSFKPVEPGVYLLPEQTRRAPRLYTSVFHETRYYTLVLIDADV--PDPENSTFTTYLHWLQPNIALSS-AS---KYIPPHPQRGSPYHRYCLFLLPHVNEK-LS-IRIGFDVRAFCEEHGLQGGGAHMWREVWNEAVTDIYKH--LKQPEPRYGKFSK- Fusgr1 --MRPISRRPFTSAAIRRPN-TVLPAFQEARKILSVDREEKLGKIQKEIEKISRLEAKKPEIKDMRLGLRKYVEELKILADANDPVVKKRFEDGDMNKPIYRHYAEAKWRSNQRIHQFSIVPDVLEPTADVQLYF--VPPGQIVDSIVSEKAPRLRVQVFDGERLISIVVLDSDV--PNPDSDTFNKRCHFLAANIPLSPNDTLALPWMPAFSQKGAPYHRLGIYLLEQEPQK-ID-VRDGFSLKSFRDKFNTTPFGFNMFRSVWDENTAAVMARSNIEFRPTRVHKYRHL Galma1 -SSTV-PRATL--SVAS-SISLENPAYDLALQYLHQDSHNLKDEVNDLQKAIDEKEALYSTTLDEELKLLEKLNIIQVQSEINLPHVRWSVNNADMSNVTHRHLLEQKWRKMERIHQMGVVPDVIRPSIDLHVAAGQVEPGVFLKSKQTLVPPKLYATVFHDVRLYTMLLIDPDV--PHPEAETFTTFLHWMKPNIPLSA-T----SYIPPHPQRGTPYHRYVCLLLPQPPAH-LD-IRLGFDMRAFAERWDLNGGGAHMWREIWDEDVSAIYKD--LEQEEPRYGKYIL- Ganpr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----LLS-RTIITNSFN-SSQKDSDAYDEALKYIYEDKAQKYEEIRLIDIMIEKLMKN---QFDQELELKKKKYNLQVLAEINDPEVRWNFKNGDMSIPVYRHLREKYWRKMQRITQMYVVPDVLLPMIDLEFKFDIIEPGVFLFPAQTRKEPTVILNNFHETLLYTLIMVDPDM--PDALNKTYQTEWHWLITNIPLNV-TK-ILPYIPPHPPKGTKYHRYTLAILEQPNQK-II-IGRVKDVREFMSDYNLKLRGASFFREVWDEEVSKIYAN--LGIHEPKYGKYTNL Hisca1 ------------------------------------------------------------------------------MADINDPVIKKRFEDGDMNRPIYRYLADQKWREVQRITQMKVIPDVLDPIVDVKLAF--IPPGEFVDSRVSSMPAKLNVQTFEGEKLLTVAVVDLDV--PDPEHDSFGFRCHFLAINVPISPTESVIFPWLPPYAQKGSPYHRLSIVILEQKDAA-LD-LRDDFRLRSLQTRHQLKPIGVHLFRSKWDENTESVMKEFGIEFRRKRIE---SF Klula1 -GLHSSAKLGLASESIKKPPSLKRRMFRLSYEFMSKRAEEKYSQ--------------LEN------AKVR--AKLETEAELHNPEVQYNFQYHDYAVPVYRRLGLKHWESMQRLETLSVIPDTLQPRVQVNLRFKWVEPGEILSSNTTSMVPTIKIQEYEEKQKYTVVIVNPDE--PDVLNDTFKTTLAFGLTNLKIDYNDNILADYIPPVPEKNVGKQRFSVWVFRQN-D--LE--RENFDIREFVRSHNLDPVGAHVWRSEWDSNVANIREKYG-------------- Lacbi2 -SCRA-PRLTV--ATDS-AISTESPAYDMALKVIKTDSFRLKEEAKELRTRIGLAENTFQELLDEQLAMRVKLNILEVQSEINLPDVRWRVANSNTKKPIHRHLVEQKWRKMERIYQMGVVPDVIRPSLDLRVVAKEVEPGVYLLPKQTLEPPKLYVNVFHDTRLYTMLLVDPDV--PDVHNESFTTFLHWMKPNIPLSC-EH---KYIPPHPQQGTPYHRYVLLLLPQPPEH-LD-IRLGFNVREFTRHWGLKGGGAHMWREIWNEDVSTIYKD--LQREEPRYGKYIS- Lenti61 ------------------------------------------QELEDLQ----------AKALEE---MREKVRVLEIQAEANLPDVRWKARNGDMSKPIYRHLLEQKWREMERIYQMNVVPDMLHPSFDLRIRYKQVEPGIFLVPEQTRRPPEVYTTLFHDTRLYTLLMVDLDV--PDTESQSFTTYLHWMQPNIPLSA-ST---RYVPPHPQRGTPYHRY---VLPQSSEP-ID-IRLGFSFRAFAEQYGFRGGGAHMWREQWDETVSHIYKF--LKKDEPRFGKYL-- Malgl1 -------------------------VYDEALKHIEHDSAALRDQIAKEKQQ----------ST----DVQERVYALEVASDINQPSVRAQFRRGSMEKPVFRHMREQAWRQIERIRNMHVLPDVITPTVDLEVLF-------------------------------------------------------------------------IGDHGGQGGST------------------L------------------------------CS--------------------- Mellp23 -STNHFNRSYLRNQSKR-EPPTNLPAYDEAIAFLKQNSKQLELKLGELQLKLKENPND---------NLKKTITKLEIESQINDVNVRVRHKAGDMSKAVYRHLKEKEWREMETVHRLRVFPDIIAPTADLRANF----VGTFISASKSITPPTIRVQVFHEGELYTLMMVDPDV--PDPSNQSFTPYLHWLVPNLPISA-TS-QLSYIPPHPARGSSLHRYTLLLFKQ--SK-LDSLRLGFSARDWIQSTNMQASGVISWTCKWREQISNIYKN--LNIPEPYYGPYTPL Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----SFPRS---CSAMP----SAAETFDEALKVIAEDKAKRLADIKNMEASLAQLIKA---AKDTEIALKEKIFKQEAYAEINDPEIQWQFKNNDMSKAVFRFMKGKQFKRQQRTAQMFVTPDLFTPSVNVQLDFGYFETGSFLLPGKTIKEPKVNVTSFHEQRYYTVALVDPDM--PDVENETYKQQLHWLIANVPLSA-TQ-VLSYLAPHPPKGTKYHRYTLLLAEQPNDK-IQ-MSRETTLRDLCSHFKLEVKGLTFFRQVWDKDVSRIYKE--LQQDEPVYGKFIHM Mucci2 ---SGLSK----CSSRL-----NASAYEEALKLIQIDKKERLNMLERLEKEITRVAKN---ATPAQIALDALKFDLQVKAELNEPEVQKNFKLGDMEKPVYRYMRQKQFEKMERLTQMSVIPDVLEPTVEINVKL--VEPGVFLKPEQSIERPEIEITNFHESKLYTLMLVDPDS--PDVANQTYQQHCHWLLSNVSLSA-AS-VLDYLPPHPQKGTKYHRYTVIAYEQPNDK-VD-IRDHFDAKKLAEAHGLKATGATFFRQEWDASVSKIYSE--LKQDEPIYGVYY-- Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 -VARPLVRRPFSSTPMRKSTTT--PCFQDARKILQQDRAAKIAQIVKETEKIKLIEARDASAKQTRISLRKYIEELKILADINDPEVKRRFEDGDMTKPVYRFMAERRWRSAQRISQFHVVPDLFDPTMDVKLSF--VSPGAILDSRVTEVAPTLRMQVFDGERLLTVVVIDSDV--PDVTHDNFKRRCHFLAANIPWDPSKTVGKPWLPPFAQKGSPYHRLNVFVLEQKPAK-ID-GRENFSLKGFREKFDLEPVGFNLFRSEWDEGTAEVMERHGVEFKRQKFAKYKSL Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -ASKPLLQRAFQSTASVRPSLVTSPCFQEARKILLADREEKLKEIETMRQRLARQEALSVEAKKSRVAMQLHLERLKILADINDPLVKRKFEDNDMSKPIYRFLADRKWREVQRITQMKVIPDVCDPIVETKLYF--VQAGEFVEAKLSTDAPKLDVQMFEGEKLVTIAVVDPDV--PNVENDNFDYKTHFLAVNVPISATSTVVLPWLPPVAQKGSPYHRLSLFIMEQKDQP-LD-FRDTTLLRTLQSRYRLKAIGAHLFRTQWDDTTLEVMKQIGVELRRKRVE---SF Phybl2 ---GSLTRHNGICAFRP-----ETPAYEEALKLIQTDKKERLQMLSQVEKELVRVCKA---AQPAQLALEALRYDLLVKSELNDPQVQKDYKLGDMGRPVYRYMRQREFQKMERITQMNVIPDVLSPKVEVSIKLSVVEPGVFVQPEQTVKKPEIEITNFHDTRLYTLMLVDPDS--PDVANQTYQQHCHWLITNVPLSA-TE-VLDYVPPHPQKGTKYHRYTLVAFEQPKEK-VE-IRDNFDIKTLAETHNLSVSGASFFRQEWNPSVSKIYED--LGTQEPVYGTYF-- Picst3 -IATRNVALKLNSPEVKQPASISDYTFKQAYELLQQEAEVKYKEIEGYKKRLGEAKSTKEV-------LKKSIDKLLVDAEVKNPEVLYNVEYTDKSQPVYRHLLKEKWEAMQRLEQLHMIPDTLDPKVDVKVKFDWVVPGTVLPAFAVSQPPTIQIQEFEEKNLYSIVLVNPDT--PDLKTNSYSTTLQYGLANVPLDNVDNTFKDYQPLVPEKNAQTQRACLWVFRQS-E--LT--RENFDIRDFALKNNLTAVGAHIWRQRFDRSVNYVRNKYG-------------- Plicr1 RSAST-ARATL--SVEA-PISLDRPAYDLALEYLKRDADALRAELE--------------QLL-------EKARILEVQSEINLPDVRWKTANGDLSKPVYRHLVEQRWRSMERIYQMNVVPDVLHPSFDLRINFKPVEPGVYLLPQQTRHSPRLFTTVFHDTRLYTLLMVDPDF--PDEEVQGFQNFLHWMQPNIPLSS-SS---PYIPPHPQRGTKYHRYVLLLLPQSS-E-IT-VRLRFDVRGFMEKYGLKGGGAHMWREVWDEDVSKIYSD--LKAEEPRYGKYI-- Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 -RSSRLTR---QIQSKT-SSPSTSSAFQESIKFLKEDSERLQQKLKEEQT----SADS---------QQPEEIERLEILSEINDVQVRKNHHLGDMSKPIYRFLEQQRWRKMETIHKLRIFPDVINPTVNLKVKYRLINVGNFVPSSKSMDPPVIQAQVFHEPRLYTLVMVDPDV--PDPRNHSFTTFLHWLRANVSISA-TTEEIKYIGPHPAEGSGTHRYTIMLFEQ--GP-ID-LRPGFSLRRFSSQIGLKPAGVMAWISQWHKRISSIYRD--LQIHEPRYGSHTPL Punst1 -RTST-ARAAEAQTSSA-HISPQRPAYDEALRYIVWDSAVLTEEAQQLKKQISEKE---EQTVQESISLKEKANIVEVQSQINRPEVRWKFRNGDMTQPVYRKLTDLKWRTMERIHQMNVVPDVLHPTIDVRVTFKAVEPGVYLVPEQTRKPPHIYVSVMHEERYYTLLLVDPDV--PNETDGTYQTYLHWMITNIRLSS-T--PFPYVPPHPQKGTDYHRYTLLLLPHAEKR-ID-IRQNFDVRGFMAEHGLVGGGAHMWREVWNEEVSKIYQD--LKTDEPRYGKYGPA Rhior3 ---SSVSR----CASK------NATAYEEALKLIETDKKERLNMLNRVEKEIARISKN---GTPAQLALDALKFDLQVKSELNEPEVQKNFKLGDMSKPVYRYMRQKQFEKMERLTQMNVIPDLLNPTVQVNINL--IEPGVFIKPEQSIERPEIEITNFHEKRLYTLMLVDPDS--PDVVNKTYQQHCHWLLTNVPLSA-TE-VLDYVPPHPQKGTKYHRYTLIAFEQPNDK-VD-VRDGFDVKLLAQSVGLKPTGATFFREEWDDSVSKIYSE--LKTHEPVYGIF--- Rhoto1 VRPCS--RTRAASAAPA--------AFDAAVDYIARDRQQKLDKLEQLR------------AT------ETQLEKLEVEAWSNDPETRWRARNGDFSKPVYRHLAERAWRNMQRVTQMNVIPDVIYPELDLRIQ-ETIEPGVFTLPAQTREGIEVSAQVFHEEKLYTLLLVDPDV--PDELNTSFTTYAHWLIPNIPLSA-TT-TLSYTPPHPQNGTPYHRYTLLLLSQP-SP-LS-LRRGFDVRSFVAQHKL-PKGVSFFRQVWDRDVSAIYRE--FQKPEPRFAKYELY Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -SIHTT-KLSIQSSKVKNPPSISRRIFRMSYDFLEQRSSKFYEL--------------ANK------PLKK--DALLIKAEINNPEVQYNFQFNDYDVPVYRHLGKQHWESMQRLETLAAIPDTLVPRAEVNIKFKWIEPGEFLSSNVTSMRPIFKIQEYEEKQLYTVLIVNPDV--PDLSNDSFKTALCYGLVNINLTYNDNIIADYLPPVPEKNAGKQRFVVWVFRQPLPNMLE--RDDFDIRQFTKKYNLTAIGAHIWRSEWDAKVAAVREKYG-------------- Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 -------------------------VYDLALRLIEEDSQAIKNEVAQARKEVEALAQEVNGQLEE---KRRHLEVLEVQSEVNLPSVRYAVETGDLTKPSHRKILENKWRNMERIYQMNIVPDVLHPSINLKCNFAPVDAGAYLSPAQTIDPPTLYADVFHDTRLYTLLMVDPDV--PDVENQTYTTYLHWMA-------------------------------------------------------------------------------------------------- Schpo1 ---------TISNVCRAR-------AYRSSVKLIQEYSEKVHKK---LQAKLLENPSETSP------------ERLQVLSQINLPEVRSKFH--DYTNPVFLYMLKQQWEDLQRLEQMKVIKDSFSPSVDVQLGFDSITPGTILPSTVTVKTPWLSVLPFNKKNHYSVITLDLDV--PNYETNRFETHCNWLLTNIPIEASKR-FFQYRPPIVHRGEDKHRILTLVLRQK-SS-IS--RERFDLSEFCSIYDLEPVGAHLWRSGWDSDAVALLSKH--------------- Sorma -VARPLVRRPFSSTPMRKSTTTTPP------GILQQDRAAKIAQIVKETEKIKLLEARDASAKQTRISLRNYVEELKILADINDPEVKRRFEDGDMTKPVYRFLAERRWRSAQRISQFHVVPDLFDPSMDVKLSF--VSPGAILDSRVTEVAPTLRMQVFDGERLLTVVVIDSDV--PDVDHDRFSRRCHFLASNIPWDPSKTVGKPWLPPFAQKGSPYHRLNVFVLEQKAAK-ID-GRENFSLKGFREKFDLEPVGFNLFRSEWDEGTAEVMERHGIEFKRQKFAKYKSL Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 LRTFT--RTTASSSTSS--------AYDQALAYIAQDRELKLKQLEELK------------VE------QAVLEKLEVEAWSNDPETRWKANNGDLSKPVFRFLAERKWRKMQRVTQMSVTPDLIAPEADLRIR-EQIVPGVFTSPADTREGIEVSAQVFHDERLYTLVLVDPDV--PDELNQSFTTFAHWIVPNIPLSA-TS-ALPYIPPHPQNGTPYHRYTVLLFAQPQST-LQ-LRLDFDTRDFAAEHKL-AKGVSFFRQKWDKSVSSIYEE--LQQPEPRFGKYEVV Stehi1 -RISA-ITTTLQSSAPA-SISLERPAYDEALRVISRDAKIVQKEAS--------------EAK-------EKLEILDIMGHVNLPDVRWKARNGDLSKPVYRHLVEKRWREMERIYQMKVVPDVLRPDIDIRINFAPVEPGVYLVNEQTTNPPRVYATVFHEPKLYTLLMVDPDV--PDTESQSFTTYLHWLQPNISLSA-ST---PYIPPHPAKGTPYHRYTLLLLPQSSEP-IT-LRLDFNVREFVAKYGLTGGGAHMWRSVWDEASSKIWQD--IKKPEPKFGKYFLE Tapde11 -----MKRRSLSTQAATASNDSTSPAFDLALDIIKNDRQLTKQKMHATKKKIKTLETKPDSLKTSQLDLKVYHRQLEGLLDINDPEIHWRHARGDLNMPIYRHLAQRKWQEEQRVTQMSVTPDIISPTVDVRLNFGLFEAGEMLNSRESSIAPKIEIQSFGDSKKYSIAIVDQDV--PDEANDAFKSYLHYLQTDVVLSPVEHVIHSFIPPHPHKGTPYHRYTVVVWEQPEAP-QP-NRENFDAQKFAQQNGLHAVGINFWRQVWDENVSSVMADYPVAFVEKNFR----- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LSAHIRTPRPYASSTVTS-LSASDPAYDTALSFLSSHRSNLLKRLEALRSAHP-NPSP---------DVQAKIDHLSLQADINHPPLRRLFRQTHMHLPVMRHLAERHWTRMQRIETLQIVPDLVLPTSSVRLVF--DKPGSIQRVWNLETPPKLHMQIFHPEGRYTLLVIDPDS--PDHLSQSYAPRLHYLKRDIPLTVSSG-EAKWEPPAPAKGSGNHRYVFVVIQQPAET-VENVRENFDLRTYLKERGLDVVGVTLFRAKCTEEIKKVWKEYR--EEMPVYGREREM Trire2 -VARPLARRPFTSGAAR-PN-SVLPAFQEARAILAADRQEKVAKIREQLDKIAALEAKDAAMKETKLSLRRSVEELKILADINDPLVKKRFEDGDMNKPIYRHYAERKWRSAQRIKQFSIVPDVLDPLADVQLFF--IAPGAVVNSLVSENPPRLRVQVFDGSRLVSLVVLDADV--PDAENDAFSKRCHFLAANIPLSPNDTLAVPWLPPTSQKGAPYHRLGIFLLQQKPVE-LD-VRDGFSLKSFRDKFQLTPVGFNMFRSVWDENTAAVMARHGVEFRPARVHAYRHL Umbra1 ----MLSR----SAARS-----EATAYDEALKLIAQDKEYRYSMLKKVEKELAKVKKA---TQKQQLRLQQLAIDLQVKAELNDPEVQWRFRNGDMNRPVHRYMVEREFQKLERVLQMRVCPDIFDPTAQVIVEYSVQEAGIFLQPGETVKPPTVSFVNFHETKLYTVMMIDPDV--PDQERQTYQQQCLWLNTNVPLST-TQ-ILPYVPPHPQKGTKYHRYTILILEQPSGK-IE-VDKRFDTRSFIQQYQLSPRGVSFFREVWNEDVSRIYAD--LKEREPVFGKYLLL Ustma22 -ASRAAFRNSSASSSSR--------AYDEALSFVRSHSESLRSRMSMLESDHAELSAS---------ERAQLKESLEIASLINLPWIVSAFEASDASNPALRHLRERVWRNMQRCTLMHVFPDVITPLVDVSVAFGDVLAGVFVEPKDTVDPPTVSVNVFHDVKLYTLALVDPDQ--PDEPTQSYKTSLLALKTDIALSA-TTMAVDYIPPHPQQGTQYHRYTTVLFEQSTDD-AS-LRHDFDVAAFAQRRALTPAGIHFWRAKWTPQISTIYAT--LNTQEPRYTKWFA- Walse1 --TRTIKR-----------------VYDLALEVLAEDKKRVQRELQQLRSD----------AVDQK-EYEKRIKLLEILEGSNDPEVRYNFENGDMSKPYYRYLAEKDFLRLERLHQMNVVPDVFTPSVELVLDFRPVIAGSFVRPGLSFDKPSIDIKIFDRESLYSLLIVDPDV--PDADNEKYTNYLHFLKSNLKLSANTT-TVGWIPPHPAQGTKYHRYTVLLVEQTNQP-SD-VRHGFDSRKYVESMNGRVVGGHMWRAVHDADSSKVFKE--LKINEPIYK----- Zygro1 -SLSTSTRFSIPSAQIKRPPSIKRRTFKLCYDFVESKAAQVYEK--------------ASK------VEEK--EKLLAEAELHNPEVQYNFQYHDYEQPVYRLLGKQHWESMQRLESLAVIPDTLVPRTEVNIRFKWVEPGEILSTNATSLPPVFKIQEYENTQ-YTILVVNPDE--PDLANDTFTTTLSYGLANVKVSYNDNVLVDYLPPVPEKNVGNQRFAVWVFRQR-P--VE--RDNFDIRSFAKTQGLIPVGAHVWRSHWDSQADTIRAKYG-------------- [Cluster3154.fasta_al_trimmed; alignment length = 179] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 DMF-SEKTSRRAAE-LEF-SKSGLYDRVFLPPASYWRAEHARYFPHLGGRTLTGA-RSVEDVLAG-KV-SVVKVFSCETGEGLASSYFR---APAQIVEISLTESW-IKDWL-VRLMAGRLRSLVERY-FIVRESLELGNLYTGYVLVVDPQLKIRWMACGGAEKRDAELLKCVRGVQR Aspfu1 DFV-NDKHIERRKE-LQV-AKPYFREKTFKSNPRLFKRDKALYFPNMYGITLASP-KNTTSILRG-KV-SVVNVFSSVWAESQVATFTGSGSELVQKVDINLEENA-MKAWL-VRMFMWRMRANLERY-FLLKEAIGMMNSKVGYVYLLDENCRIRWAGSGPAEEGELDGLNGVRKLIQ Aurde31 RMT-DKANAAERDH-LLL-NHGHFSDKSYTAPSVLIREEFANYFPNVEGVAISDR-ESTGELCAG-RV-SLVAVLTTNLSEEHCRSFAQGSNPLFRFVQINLQESK-MKYYV-LSLFISNLRNTVPSY-MLLRDPLLMENKYVGYVFLLDKRQRVRWAGCGFASPAERDALRCAGVLLE Batde5 QKLLDDENTRDREK-LEAFSGGYWKDKLWEAPEKIRSGQYSHLVPNVSGTLMNGE--DIMSYVSRHKV-TLVVFFFNAFGEQQTRSFVNKTHSDIDLLIVNVEEKL-FRAPV-LWLSRPYVKWNVQRY-MIKRTECGMVNTVLGWVNLVDSSGKIRWQAHGEATPKELAAVNLAKTMLH Botbo1 ELL-DEKHLQKRQH-LQA-TRGYFHDKMWVAPKVLIREDKALYFPDIAGTALNPK-EHTTTIGAG-KI-SVVSMLSTKISEMHTQSFVTQFDERFKYIQINIQENP-LKSFL-VSLFLASLRQAVSSY-LVLREPLGMENKHIGYVYLVDSDLRVRWAGCGFAAEGESEALNCTRVLVD Botci1 DFV-NDKHLEKRKK-LAM-AKPYYREKSFLAPPRIFKADRALYFPNLSGRTLEPD-SNTTPILEG-KV-SVVSVFSGAWAENQAATFASNNKGLAQMVHINIEENY-LKAMI-IKFFRSSLRKKLKRY-FVMKDAIGLLNSKVGYTYILDGDCKIRWAGSGPAEEYEKDVLKSVSRLLE Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ELF-GKSKERRQKQ-LDL-KHSPIYEKIFTPPVSYFRQDKSLYFPDFIAKTLAGN-QSLYDSLDN-RL-SIVKLFSSVAGEQCTRSYFKEEYPHTQILDVNMPQSW-IKGFV-TNLSTGNLRKTLENY-FIIREQLYCDNQCSGYIYIVDSMGKIRWATSGYATPEDLKLMKVVKGVQR Cangl DLF-DAKTEERIKE-LEF-AKSGMYEKLFLSPESYWKADKALYFPHLSGRTLSSEDHNVEDVLRG-KT-SVIRVFSTQVGDKISREYIK---QSCQVIDINFLENK-LKSWL-FKLSLNNLKSTVDNY-WLMRERLLINNVYSGYIFVVDPNLKIRFMACGPASADEFNKLKVVGQLSK Capow DAATNEQATKNPKD--QA-DAPTTKKKPFEASTTLSHSKYAVKFPSRVLTAINGQ-TDLSEAFTR-GI-SIVSVAFDQFGALRNASFTHGSNPYVNDFEILMNRMP-MMRVL-QPMFNRNLLAAIGSVFNLVDEELAIRFYTGNFIYLVDEQGLIRWQAVGKALPREVTAMHCANTLLS Catan2 --------------------------KLSIAPTTLTDAAISKRFPALTVTPLSET-SPMLPRLQG-QV-TLVTLACSTYGDNQTKSFEM---PHVPVYQISMADTP-IKAWI-LKLNLRYTRAKVDKY-FVALEELKVTNKYVGWVFLVDHRGRVRWRANGVATEQE------------ Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 DYS-GQRNLEKRKD-LKW-GTNYFRDKTFMANPRIFKKEAALYFPNFHGDTLEGK-DDTTNVLTG-KV-SVVNVYSSQWGLNQVETFTGQHPGVAQMVDVNIEENT-MKAWI-IALFQWRLKASKSKY-FVIRETIGLLNGRVGYIYLVDQDCKIRWAGSGNAEGTEMEDMKGFAKLIA Coere1 QKMRDETRAK-----IDI-GHSYFQDKLFEAPQQLIKSGRAKYLPNLEGKTLAGV--DIVDLCRN-NT-TLLSVEFTKFAEKHTQSFVSAGVNAIQLVQANIEENW-AKALV-LKLCLPYLRKSMANY-LVLRKALGIANPLIGYVFLIDANTRVRWYANGLAVKSEAETMRLTRSLAK Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 ELM-DDVRMAQREQ-LEV-GKGYFTDKTWIAPNVNIREDKALYFPNMMGTTLDGK-KHTTSICRG-NI-SVVSMLNSRMSEIHVKGFTELSNPLYKYVQVNLQENL-LKSFL-VSLFLSSIAKATPTY-MVVREPLGMVNRHVGYVYLLDENLRVRWAGCADAKAEETAALKCVGVLLA Copci DLM-DDYRMAQRRH-LEA-NKGYFHDKTWIAPKVLIREDRALYLPNISGSSLLDK-SHTTTLCFG-KI-SVISMLSTKISEIHAKAFTDLSNPHYQYIQVNLQENV-MKAFL-VNLFLSGLRKTVANY-LIVREAMGMTNSRVGYVYLVDENLRIRWAGCADPTAEEIQSLSCTGVLLK Croqu1 KLV-DESRLRERKH-IEV-SKGYYHDKLWTAPPSLIREERSLFFPDIKGIALANK-QHTTDLFED-KI-TLLAIESTRMSEEHTRSFYTAGENNFQLVRINVQENP-LKSWL-VSLFINKLRQSITKY-LLIREPLGMVNKLLGYIYLIDHNKKIRWAGCGFANVEEMRSLVSSKSLLK CryneH991 EML-DDRAKAKRKA-LEA-KQGYFHDKLWIAPNVLIREDKANYFPDISGKSLLGK-NHTTDVFKG-KA-TLVTVISTRLSEEHVRSFVQEGHPDFQYLTINHQPNA-LKSLL-VSFFTSSLKRIVPTY-LIVIQPLGLGNSLLGYVFLVDHNAKVRWAACGLATEDEVKSFRAAAVLVG Crypa2 DFV-NEKHLKRREE-LQM-ARPYFRDKTFIAPPRLFKHDRSLYFPNLFGHTLLKS-TNTTPVLQG-KA-SVIAVFSTGWAERQTLSFTSEYKGRAQLVRVNIEDQSRLRYWI-LRAMAPFVRRNFDKY-FMIRESIGYLNSKVGYVYLVDGDCKLRWAGSGPAQPDEVQSLKGLAKLLD Debha1 KIF-GEAKERRQKQ-LEI-AHSPFYEKIFTPPVSFFKREKSKYFPNFGGATVDGR-DTLFGLLEG-KV-SIVRLYSTVSGEKCSETYFNAEHPMSQIIDINIPQNW-LKGLL-VKLSSGSIKRSLSKY-FIIKQKLMCDNTCSGYIYVLDHQGRIRWATSGYADPAELSLMKCVRGLEK Dekbr2 -----------------M-AYGGMYDRLFAAPPSYFKREKALYFPNFAVRSLAND-QELLDSVAGSKA-TILRVFSTRTGEEMTKEYFKQSYPDAQILQLMLSDSW-IKYLLHVYVSGPKLRQLVERFLFADRERLLMTNLYSGYVYVLDNSSRIRWVGSGWPEGDEVTNMNAVRGVSR Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ----------------------------------------------------------------------------------------------------NLQENP-AKAFL-VSLYLSSLRRNIPFY-LLLREPLGMNNKHIGFVYLVDENLKVRWAGGGLAVPQESESLRCTKVLLE Fusgr1 DFV-NDKHLQRRKE-LKI-SRPYFRDKSFIAPPRLFKAELSLFFPNFYGETLLKT-DDTTPLLSG-KA-TVINFFSSRWAEQQVGTFTSQHAETTQLVNINYEDNA-GKAWL-IRFFMGSLRKQFDKY-FLIRESIGLLNSKVGYVFLVDKYCRVRWAGSGTAHPVETEGLKGLSRLVD Galma1 DYM-EESLTAQRRH-LEA-SKGYFHDKTWIAPKVLIREDKSLYLPNITGTTLDNG-TDTTTMCFG-RI-TVLAMLGTQISEAHAKSFTYSQNPLYQYLQINVQENL-LKSFL-VKLFARSLRASVSNY-LILRDPLSMTNSKVGYVYLIDEHLRVRWGGSADATLQEAQSLSCTGVLLK Ganpr1 PKLKDQSLMKEREQ-LEAFDEGYWDDKFSEAPNDLIPYELAPTLPVLGGRLLSGG-TDPLTVATKHKV-TFVGILFSKFAEAHVDSYLKKNNPDVGLMLINVEENS-AKAWI-QAAFRWLMKMKTDRY-MLHRRTLGLFNKYLGYAMLVDRWGKVRWMAHGPASEKELEFLSNAVELLK Gloin1 ----------------EY-QTSYWKGKLWEANEEAIKADKALYMPNINARSLLKT--DTTNLLRD-NT-TLLTVFFNRFGEIQVKSFIESNRPKIQLMQLNIETNI-LKSFI-IKLFIPNIRRITKTY-ILLREALNIYNAYRGYVFVIDADCKIRWFAHGYATPKEIETMKIIKDLDR Hisca1 DFV-DEKHIVRRKE-LQA-AKPYFREKTFISNNRLFKADKAFYFPNISGRTL-SP-TDTTPILRG-KV-SVVSIFSSLWAERQAASFVGDAPKEAQRVEINFEDNV-LKAWL-IRLFMWRMRKSMEKY-FLLREQIGMMNSKVGYVYLLDHECRIRWAGSSIAEEGELDSLNGLRKLID Klula1 DLF-NEKTGKRAEE-LEF-RKSGFHDKIFISPPSYWKADKSLYFPHVVGQRLSDNKENVEDTLKG-KV-SIIRLFTTDVGKNLINSYFIDGLKSAQIVEINLAENW-LKTMV-VKLVKNRYASIVDKT-FIIREQLQINNLYSGYVFVVDENLKIRWAACGEATQKDFNLLKCVKAVRS Lacbi2 ALM-DDVRLAERRH-LEA-SKGYFHDKTWIAPKVLIREDKALYLPNISGKSLADK-MNTTTMCFG-RI-TVLAMLGTQISELHVKGFVDSSNPLYQYVQINLQENL-LKSFL-VNLFANSLRNVVPNY-LVVREPLGMTNSKVGYVYLIDENLRIRWGGCADATVEESQALSCTGVLLK Lenti61 KFI-DDKRMEERTH-LEA-TRGYFYDKTWIAPKVMIREDKALYFPDIQGTALAGS-EHTTNLLQN-KV-SVVALLTTRISEIQTAQFLESSNPLFQFVQVNLQDNM-LKSFL-VSLFASGIRKKVPTY-MILRQPLGIANKHVGYVYLVDPKLKIRWAACADPKSEEVSALTCTTVLLE Malgl1 -------------------------------------------------------------MLMG-RV-SIVAIVTSKVSEEHTRSFYEHTYPHFQLVQINLQENS-LKAYL-ISLFLSSLRSQVSTY-LLVREPMGLHNKHVGYTYLVGPDGKIRWAGSAFAEPDEARTLACTGVLLD Mellp23 KLV-DESRLRERKH-IEV-SKGYYHDKLWTAPPSLIREERSLYFPDIKGIAISNK-QHTTDLFDD-KV-TLLAVESTRMSEEHTRSFYTAGEPDFQLVRLNVQENP-LKSWL-VSLFINNLKRNVSRY-LLFREPLGMANKLLGYVYLVDWDKKIRWAGCGFANAEEMRGLTSSRALLK Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----------------DF-QSGYFAEKLWKATSSMINADKALYMPNIIGTS-LKT-SELVDLLRG-KI-SLVAISGTRFGEEHTESYMTNNSNKVQLVELNIQENP-LKAGL-VRMMVPFVKKTIANY-VLLKDPLSMQNSYLGYVFLVDSNCKIRWGAHGPATETEVKTLESVQKLSE Mucci2 ----------------EA-TKSYFADKMYFASSQLVKPEKAGYMPNFEAQDLSRQ--NTTEKLVG-KT-TLMTFVYAKFGEPHVNTFIKKDQKDIQVVEVNVQENM-LKQLL-LKAFVPSIRKNLENY-CLTRKCLDMTNQYVGYAFLVDENCKIRWTAHGEATAEEVGNMAMTDYLHE Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 DFV-NEKHLKKREM-LKI-SRPYFRDKTFLAPPRLFKADLSLYFPNLHGRTLAKD-DDTTPLLEG-HC-SVVTVFSSMWAENQIRTFVSQSGGRAQLVQINIEEDA-MKAWL-VRLFMGSLRKKVKRY-FLIRESIGLLNSKVGYTYLVDHNCRIRWAGSGDAEGDEKEGLKGVQRILD Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 DFT-NDRHIKRRKE-LQV-AKPYFREKTFVSNPRLFKADRALYFPNMHGVTLASP-KNTTTQLRG-SI-SVVNLFSSVWAESQVATFTGSGGKLVQRIDINLEENR-LKAFL-VKTFMWRMRQKLSRY-FLLKETVGMMNSKVGYVYLVDSECRIRWAGSGPAEKSELEGLAGVRKLIE Phybl2 QKLRDAAHAAERRH-LEA-TKSYFADKMYHASPKLIKAEKAGYMPDFEGTNLERK--HTTDILKD-KI-SLMSFVYAKYGEPHANSFIEGDKKDIQLVEVNVQENF-LKQLL-LKAFVPTIRKNLANY-VLVRKMLDMTNQYIGYVFLVDENCKIRWVAHGNATSEEIGNMGMTEYLNE Picst3 ELF-SEAKERRQKK-LEI-RHSPFYEKIFTPPISFFKKDKALYFPDFISSTLDGQ-SSLYEILAD-KV-SIVRLYSTVSGEQCSHSYFKENHPQSQIIDINIPQNW-MKGFL-LGLSKSNIKKTINKY-FILREKLMCDNMCSGYIYLLDHNGKLRWATSGYANDEELALMKCVRGLEK Plicr1 ALM-DDVRLAQREH-LEA-TKGYFTDKTWIAPPVNIREDVALYFPDIVGMSLDTK-EHTTNMCYG-RI-SVIAMLSSKISETHVLGFAQKDNPLFQYIQINLQENI-LKSFL-VSLFLKSIRSTIPTY-LVQRAGLGMVNKHVGYVYLVDENLKVRWAGCADAKPEEAAALGCVKVLLT Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 KLV-DQARLQERKH-LEV-SRGYYHDKLWTAPPSLIQDQRALYFPNISGVALSNK-EHTTDIFAD-KV-SILAVESTRMSEEHTRSFYGAEEDNLQLVRLNVQENP-LKSWL-VSLFINNLRKTVQGY-ILVREPLGMVNKLLGYVYLVDWNKKIRWAGCGFSNAEEVSALSGTRTLLK Punst1 DLL-DDKRLAKRQH-LQV-GTGYWSDKTWIAPRVLIREDKALYFPDIAGTALDSG-QHTTALLTG-KI-SVVAMLNTRMSEIHASAFADLSHPSYQYVQINLQENL-LKSLL-VSLFLSSIRKTVAGY-MVLRDEMGMVNKHIGYVYLVDDKCRIRWAACGDAKEEETQGLGCARALLT Rhior3 QKLRDAAHAAERQY-LEA-TKSYFHD------------------------------------------------------------------------DANLPYHS-LNLVL------------------------------------------------------------------- Rhoto1 DLL-NEKRLEERRH-LEV-ARGYFHDKAYMSPKTLIRDELALYFPNIEGISLATK-EHTTDLFEN-KV-SLVAFSSFRSAEEHINSFVRKGDPNFQYVYINLQENP-LKSFL-VSMFLSSLRKQVRTY-LLLRDPLGMPNKHVGYVFLVDWRKKIRWAGCGWATVEEEEALRCAHVLVQ Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 DMF-DEKTNHRVKE-LEF-SKSGLYDKLFIAPVSYWKEDKALFFPHLIGTAMDGTKQNIEDMLRG-KT-SIVRLFSTASGDKLSSSYFQD--SNVQIIEVNLVENA-VKSAL-VK-TLARWANRVPFY-FEVREELFCNNVFSGYVFLVDQQLKIRWAACGEATPSEKEALKFAKRL-- Salro EALQERKNMEKRQA-IQFKTISPLQEKRHEAPTTLAMAAEAPLFPHVKGTSVAGSPVNPA------AI-TAVLIFFREISKPMVNAYETQEAAQASHADLDTFTLLPLEGRL-QSLFSSSVSAAMDHV-CIIKDELSLFSPYTCFCFILDPRGRIRWRAHGHPSAAEIATIVVVPGLQR Schco3 QIMLNEGVQKERQH-LQA-GKSYYEDKTWIAPKQAIREDKALFFPNITGKSLLGN-QHTTTLCFG-RI-TVLSLLSTRISEIHSARLVQAQHPLFQHVQINLQENL-LKSFL-VSLFTNSIKKQVDHY-LVLRGPIGMDNEKVGYVYLIDENLKIRWAAGGEPEDSEIEALTCTGVLLR Schpo1 KPA-SSSPEQRQKE-LEM-KRSTIQDKLFYSPPRLFKEKSALWMYNFHGKSLRNQ--ELYKDWQG-SP-FFFALFSNAFGENQCRNWIQAPFDYLPVRYANVQSNL-IKYWL-QKIFIGKVKRSINEY-IT--PEIGWNNKLVGNVYLIDDSCKIRWLGTGDPTNVEIENLTAIKFLVN Sorma DFV-NEKHLKKREM-LKI-SRPYFRDKTFLAPPRLFKADLSLYFPNLHGRTLAKD-ADTTPLLEG-HC-SVVTVFSSMWAENQIRTFVSQSGGRAQLVQVNIEEDA-MKAWL-VRLFMGSLRKKVKRY-FLIRESIGLLNSKVGYTYLVDHNCRIRWAGSGDAEGDEKEGLKGVQRILD Sphar -----------------------------MAASDLTDAKESKALPTISGDTLSGR-KSLQPELDN-KI-SLVLVAVRDIARPQLELYRTASHSATQVIEVSLIERL-LFRYL-SFLMISNLKKVIDKC-LVIVEQLDISNPLFGYAYLVDGRGRIRWRAHGTPAGEELVILDLTEKLIK Spipu1 EYL-DDANLREREELLAF-REGYWDDKLWEAPRRMRNANASPLVPNPQSRTLAGQ--DVMSLVRNKKA-SLVTFMFSAFGEPHVNSFADKDVPEVQLVQLNIEENW-VKAPV-LKMLTPVVRWRVDKY-LLARRSAGMTNNVLGWVNLVDSQGRIRWQAHGLAKDHELATMKLTRKLAG Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 EFM-DEKQLEKRKA-LQA-SSGYFYDKTWMAPKVLIRQEKALYFPDIVGHRLDNG-EHTTAMCKG-KI-TVVSMLTTKISESHAQAYTEASNPSYQYLQINLQENV-LKSLL-VNLFLSSLRSTIPTY-LVVRDSLLMTNSRIGYVYVLDEDLKVRWGACADAKPEEEEALRGVGVLLN Tapde11 ALF---TTPGQHKQ-IEE-GGSYWADKQWMAPKHLFKAERSLYFPNLSGRTLAAE-EELLPLL-G-TT-TLIRVFSATSGEEHVHNLGE----DLQVIDINIQSNA-LKYGL-LKVFLGRIKALIAKY-FIWEKKLKIINSYIGYSFLLDKSGKIRWASCGSLTKEERESLKLSKRL-K Thetr ---------------------------------GAALAAH-------------GGLSHLL------FVETRVLKLFKSL-------FVSRQATPASQVDA---TLLSFDA-------DETVRAAL-----------RLFG----YALLVDAEGRIRWRGKGPATAGNVQRL-AVSGL-- Treme1 ELL-DDRHKAKRKA-LEA-SQGYFHDKLWTAPPVLIREDMAQYFPDIQGKALTGE-THTTDLLLG-KV-TLLAILSTRLSEEHVSSFCQSTSPLFSHVQINHQDNL-LKSLL-LNFLVSSLKRTVGTY-MIMTSPLGIENKLLGYVYLIDPNAKIRWAGNAMASEEEVDNLRATAVLMR Trire2 DFV-NDKHLQRRKE-LKI-SRPYFRDKSFIAPPRLFKAELSLFFPNLYGQTILKN-DDTTPLLSG-RA-SVVSIFSSQWAERQVESFVSRSGETAQLVRINYEDNK-GKALL-VKLFMGSLRKRFDKY-FLIRESIGLLNSKVGYTYLVDHHCRIRWAGSGSSHPDEVESLKGLAKLVD Umbra1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 RLV-SEHRMATRKA-IQA-TRGYFHDKTWRAPNTLIKSSRSLYFPKFTGSRLSDK-ANTVDILRN-KI-SVIALLGSKISEEHTKSFYQATHPNFQLVQINLQQNP-LKSYL-VSLFISSLRNHISTY-LLIKDALGYHNKHVGYTYLVDESGRIRWAGGAFAEHAECTALACTGVLLD Walse1 NYF--EAKLEERKRLLES-RNAYYADKTWIAPPSLIQHQRSLYFPDIKGTLLKDG-RHTSDILKG-KI-SLVSIMSTRIGQEHTKSWSEGSNPDFQFVQINSQSNP-LKSWL-VSLTLNNLRRQVDTY-LLVREHLAFDNQYAAYVYLIDQDIKIRWAGAAFAQQREIDAGKCTGELLQ Zygro1 DLF-DEKTNKRSKE-LEF-SKSGMYDKLFTSPPSYWRSDKSLYFPHITGLSLKDG-QSLEDTLRG-KV-SVVRLFSSKVGDDLCKQYLQS--KGIQTVDVNFVDSG-IKYAL-MKLFIGRLRSAVSHY-LLVRETLQINNVYTGFTIVVDPALKIRWMASGSATTDEFKTLKCVKRIRE [Cluster3155.fasta_al_trimmed; alignment length = 204] Allma1 HNVVEAVLDQF-DKLKYRPAHPDWTCLAGIVLTFDCVAIGTGLKCL----NESSTTVNDSHAEVICRRSFCCFLYQPHIRVHL-YISQSPCGDASLDALRGRNLFGVLRTKPGRHDAIPTRSMSC--SDKIAQWQC--LGLQGALLSRLVDPVTFALIIVGDVGLERAEYL--VNGRRQGAAMGKWSRISKVKRDLHWVGNDAK Ashgo11 EAICAQVIRQY-GNPSSKPARREWTVLAGVVLECRLVSAATGVKAL--PDKELGRMVHDSHAEILALRGFNAVLLQSRWQAAL-YISKAPCGDCSMDMARGRFNYGVARTKPGRADSQITLSKSC--SDKLASKTV--MSLLSSMTWELFEPVFLDYLVLPHAGFERCQAL--LNGVRNGAYVRPETIVSRARNRLGWPTTRVD Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 SLVVAATHKAF-AKLRFSPAPGTFTVCASFALECKLLAVCTGTKCL--PMERLGDALHDSHAEVLARRGALKWCLGPGVQLSM-YISMLPWGDASMGLLRGRVDYGVLRTKPGRADSPPTACMSC--SDKIATWTV--CGIQGALGSTVLRPLYIDSIIIGDQDCQRAEVL--VDGIRRGLTPRQRPSLSKAKGTLAWRESNAS Batde5 SSIATAVLSQF-NKKKGKPTIKEWTVLAGIVISPQCVALGTGLKCL--PKIMLGLAVNDSHAEVICRRNWQRYMMTSGIQFHM-YVSQSPCGDASMRALRGRSSFGKLRTKPGRADAPPTTIMSCSFSDKIAKWNA--IGLGGALLSFLVSPVYLSSLIIGDVMCRHSEVI--VQGRKQGASKKNCARICKAKNLLGWIQNDPS Botbo1 DVVASACINLY-ATHKFHPSPRHYVVLAGIVLTPHCISLGTGSKCL--PASRLGDALHDSHAEIIARRGAVRWLFEAGVSVHM-YVSTLPCGDASTLSLRGRDNYGVLRTKPGRADSPPTLSMSC--SDKIAAWTL--LGIQGALLSDIMRPVYLNSIIIGEQECERAEVL--VDGIKRGVSTKHRPRICKAKRKLGWIVSGEQ Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 NAIASTVIDTF-NGKSGKPVVREWTVLASVVANIMPITLATGVKTL--PDKVRGLMVHDMHAEILALRLFNYYLLEHDVKLAL-FISEPPCGDASMSYIRGRNNFGVVRTKPGRSDSLISYSKSC--SDKLCLKQL--VGICNATTSTLFDSIFLDYLV--TKDFHRCQVL--NNGVKNGSFIKNESIICNARQALDWVSSTAD Cangl TKITELVLSEY-EKAKGRPVTREGTIVAAVIAKHSILTITTGVKST--PNDELGKILHDCHAEILALRGFNRLLLENELELTL-FISKLPCGELSMSLLRGRCNFNYVRTKPGRIDSKATYSKSC--SDKLYIRHK--TSVLNSLTSYMMTPLYISNYVIPNHQIEEMEQI--LNGVKNGYYTKAESKVSRERAELGWLSTAED Capow DAVAQVCQQGY-ARPRGKPSQALWTVLAGIVVALSLVALATGTKCL--GASQLGTLVNDSHAEVLARRAFRRALVQ-NLSVHL-YVNQAPCGDASIFPLEAGADYGCLRTKPGRGD--RTRSMSC--SDKIALWSC--VGLQGALLSQLIEPIPLATVVVGEEAMQRAEV---LIQGKKEGANSRQSVLSKRKHAVDWLRNG-- Catan2 ----------------------------------------------------------------------------TAFTSNLDLLPTAFCGDASLEALRGRNVFCVLRTKPGRNDSIPTRSLSC--SDKLASWQC--LGLQGALLSTLIDPISLASIVIGDIGLERAEYI--VNGRKQGAAAGKWSQVSKRKRLLSWVGNDPK Cioin NTISQLCLKKF-DDKNGKPEEGQWTALAGFVKDYEVVAIGTGTTCL--GESQMGLILHDNHAEVIARRSFIRYLYHSGGSFHF-YTSNTPCGDATIFPIGKGINYGSLRTKPGRGE--RTTSMSC--SDKILKWNL--MGWQGHLLSLLVEPIHMKYIIVGGVALKRA----------------------K------------- CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 DHIARCVIDQY-DKKRGKPTSKEWTVLAGFVINLTCVALGTGLKCQ--NRKQLGDTVRDSHAEVIARRSFVAYLIEDGIRVHL-YTSLCPCGDATI---GPRIP-GSLQLKPGRTDSTPTLSMSC--SDKIARWNV--LGMQGGLVASFIEPIYLSSIVVGDNSIDRAVAL--VNGIRQGS---KRPDICKIKIELDWVCCPIE Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 EAIVNATHQLY-LAQKWNPPPKTFTILASLSLEFKVIGMGCGCKCL--PENKLGEALHDSHAEILARRCAVRWLLEEGVHLKM-YISTPPCGDASMQFLRGRNNYGVLRSKPGRADSPPTRCMSC--SDKIASWNV--LGIQGALGSHFLRPIYISAIIIGEEDCERAEIL--INGMKRGVSPKDRPILSKAKECLGWLRSGSA Copci ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Croqu1 ELVAQTVHEAY-RSRNGKPIIREFTILAGFVLLTICPSLATGMRCL--PREKLGDLLHDSHAEVLARRGLRYWLYDESVKLFL-YVSTLPCGDASMLLTRGRLGFGTLRTKPGRIDSLPSTSHSC--ADKLALWNV--LGLQGALGSTILEPIRVSGYVFGATDLVRAEVL-DRHGSRQGAPTKRRSRISKMKSCLGWIVHGLP CryneH991 DRIAQSSISLY-ETKHGKPNVREWTILSVISLVIVPVSLGTGVKVL--PHHRLGDAVHDCHGEIIARRGFIRWLIFDGVDVWL-YVSALPCGDASTLYTRGRNTYSTLRTKPGRPDSPPTTSMSC--SDKIATWVC--VGLQGGLLADLYEKVKLEGLVIGGAEAARAEII--SNGTRLGFLWKARSRLCKAKGLLGWLVSGKD Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 DRISEVIVNNF-NGKSGKPTVREWTVLAGLVAEIYPITIATGVKAL--PNRFRGAMVHDLHAEILAIRLFNWFLLDDGIKLAL-LVTEPPCGDASISYLRGRTNFGIVRTKPGRSDSVITLSKSC--SDKLCMKQL--IGITNAITSLLFEGINLDYLVLPKDDINRCQVL--NNGVKNGSFIKNESIICNRRQALDWVSTDTD Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi DKICNFSHDFFNKKKKGKPISGEWTVLATLVL---VLSLGTGNRCL--GKSSLGDVLNDSHAEIICKRSFQKFCYNKGHSLHF-YVNQTPCGDCSIFPFLIGVDYGVLRVKPGRGD--PTVSMSC--SDKIARWNV--LGIQGSLLSHFIEQIFLSSITIGDSSIYRGEVTIAINGKKMGTNQKNRSSICKSKKYYNWLTNSSD Dmel KEIAELCLKKF-ESKTGKPTANQWTILAGIVEACQLVSLGCGTKCI--GESKLGLILNDSHAEVLARRGFLRFLYQEHVEFHF-LSTQTPCGDACIL--------GALRTKPGRGER--TLSMSC--SDKIARWNV--IGVQGALLDVLIKPIYFSSLNF--ESLERAEIS--VNGKRQGVTKKKALAISKAWREIQWTKKPHE Enthi NEVQCKIKEVY-NKKKGKEQENEWSVLASLIAEYEILSIGTGSKCV----TSKNNIINDSHAEVICKRAFQLFLLEDKYDLIF-YISQVPCGDCCI---------GKTRIKPGKGE--KSLSMSC--SDKILKWEV--LGIQGGILANHFEMIRLNLIIIEKDAVMRGEVTLGARGVKFGAGKKVRSRLCQKRKVFQCVEGGWT Falba DQVSRLCVEAF-DRRKGRPA-AQWTVLAGFVLAMRVIALGSGTRAL--PRHLLGDLVLDMHAEVMARRSLVRFLLLARYRLHF-YVSQAPCGDCCVFPMQFGEGVGILRTKPGRGP--PTHTMSC--SDKVAKWVA--LGPQGALLAAVLRPVPIASIHIGEAAANRAAI---AQGVNLGASLKKRCSLSKRRRALEWLGNGGA Fomme1 DTLVTRVHARY-TACYFKQSDNQYTVLAAFVLNYKVVALATGVKCL--PTDRYGDALHDSHAEVLARRAFIRWLHEEGVKLHM-YISTVSCGDASMRFLRGRNNYTVLRTKPGRADSPPTICMSC--SDKIAVYNV--LGVQGALAANLFAPIYLSRIIIGDLDCERAEVI--INGIRRGVGPKQRPLLCKARSLVGWIVSGEQ Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 DAAVLTILNAY-SSFSYKPQHSQWTILASFFLEIKIISLATGTKCL--PATKLGETVHDCHAEVLARRSALRWIHEEDVQLNL-YVSTLPCGDASMRFLRGRDNYGALRTKPGRADSPPTLCMSC--SDKIARWNV--LGIQGALGSKFLAPLYIGAVVIGEEDCERAEIL--INGLKRGVAPKDRPRVSRAQHKLGWITSGTK Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Gloin1 --------------------------------------------------------------------------------------------------------------------------MSC--SDKIALWNV--VGLQSALLSEFISPIYLSSIIVGDDSLIRAEIL--VAGRKQGTVKSKRCSVTKAKRMLQWIKCPSQ Hisca1 SRIARLVHSHF-DAKRSKPTIHQWVPLSGIVF-LTCVAIATGAKCLSSSQMKQGMVLHDSHAEILAIRAFNHWLLE---------------------------------TRP--------------------------------------------------ATMAR------------------------------------- Klula1 DRIAASVISAY-DKKSGKPGIREWTVLSGIVARYEPISLGTGVKAT--PNEELGQIVHDCHAEVICLRAFNALLLKDVWKFAM-YISRIPCGDASMNLLRGRANYKVVRTKPGRADSKITLSKSC--SDKLTMKQM--ISICNALTWSLLSPVYLEWIVLPKVQLEDTEVI--LNGVKNGFYVKGQSIISRDRNHIGWISTCRD Lacbi2 DKAISNIFEIY-SSLSFTPPHSQYTVLASFFLRVKVLSVATGTKCL--PANKLGEIVHDSHAEVLARRSALRWFFDDDVRLNL-YVSTLPCGDSSTRFLRGRDGYGVLRTKPGRADSPPTLCMSC--SDKIAMWNV--LGIQGALGSRFLQPLHLSAIVVGEEDCHRAEAL--INGLKRGVSPKHRSMVSRVKRTLGWVRSGNH Lenti61 DAVASLVLTAY-TKLNFRPPDGQFTILAGFVLELKLISLGTGSKCL--PASRLGDALHDSHAEVLARRGAVRWFLEFGTTLNM-YISTVPCGDASTRYLRGRDNYGVMRTKPGRADSPPTLSMSC--SDKIASWSV--LGIQGALGSRLLQPIYIDRFVIGEEDCTRAEAL--INGIRRGVSPKHRPLLSKARLALGWVTSGRE Malgl1 ---------------------------------------------M--PYDRLGDVLHDYHAEVLVRRGVRSWLLESDFRLSW-YVSMLPCGEASSSALRGRTMSCILRTKPGRPDAPPSISMSC--SDKLMLWSA--LGIQGALLSRWIEPVFINQIVVSFECCASCEKL--LGGIKMGASLRRLSSVCQRKNMLAWIRTPRA Mellp23 DLVVKVIQETY-QTKNGKPIKREFTILAGIVLTTLCPSLATGMRCL--PQEKLGDLLHDSHAEVLVKRGFRLWLYEKSVQVFF-YVSTLPCGDASMLLTRGRLGFGKLRTKPGRIDSPLSTSHSC--SDKLALWNV--IGLQGALGSSILQPIHISGYVFGTSSLRYAEVI-DRHGSRQGAPKKRRSRLSKRKSLLGWIIHGAR Mnele KTISELCNTHY-NKKKGKPATDQWTVLSAIVMKYDVVTMATGTKCV-------PTVVSDSHGEVLCLRLFRLFLLEEGVSFHF-YSSHVMCGDATISQTRDR-SWSVLRTKPGRGP--VCLSLSC--SDKLMKRQF--LGLQGGLLSRFLCPIRFSSFSIGGDSVKRA----SVKGKVQGATKTSMLPVCRKKQDFGWNRKMSR Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 DNIVRECHAQF-DKKNGKPAKREWTILAGIVMEIECISLATGSKCL--PQGKQGDLLNDCHAEVLARRGFNRWCLHAGTQFHL-YVSQAPCGDATTASLRGRVDYGVLRTKPGRGDSEPTLSMSC--SDKIARWNI--LGLNSALVMPFLKPLYLKSVVTKEEALERAEVL--INGCKAGASVKKRSRLCKAKQLLNWVRGDAS Mucci2 AKIVQATLERY-NQKQGKPLVHEWTVLASIVMSIKVISLGTGLKCL--PFSKLGDVVNDGHAEIIARRGLIKYLL-PDYSLHM-YVSQSPCGDASMSALRGRFDFGILRTKPGRLDSEPSLCMSC--SDKLARWNV--LGLQSALLSNAFRPIYLDSITVGDEALERAEVF--VNGGKQGAPKNKRPSLCKTKTCLMWVQTPQE Mydma DQVALVCYEAY-KKKKGKPESGEWTKMSSVVQELKVISIATGTKCI--GKNMRGYILNDSHAEVLARRLLLKYFYQDDIKFHL-FSTDIPCGDAAIFFQLPGINYSALRIKPGRGD--QTVSMSC--SDKIMKWCV--LGLQGGVLKNFIKSIFLSSIIIANAAIKRSEV--SANGRLHGTTKKDRTSVCKAKHRLDWITKSKE Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 -----------------------------------------------------------------------------------------------------------------RIDADPTLSMSC--SDKILKWTY--LGITGSLLMHFLEPIYLYSVTIEDASLSRAEVI--VNGRKQGASPKNWSDLCKAKNYLGWMKKPKG Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 NLLAAESIKKF-NKKQGKPLVHEWTVLACILASIQVISLGTGLKCL--PYSKLGELVNDNHAEVICRRGFIKYAL---------YSSESG-GDASMSMLRGRFGFGVLRTKPGRVDSEPTLSMSC--SDKIARWNV--LGLQSALLSNIFEPVYLDSIVVSDESLERAEVI--VHGRKQGVPKGKRPLICKAKQCLTWVQTPDE Picst3 QCAIDAVVLVF-NGKSGKPVVREWTVLAGVVGETVPLTVATGVKAL--PDKYRGLFVHDLHAEILALRLFNWFLVENEVKLGL-VVTEPPCGDASMGYLRGRGHFGIVRTKPGRSDSQITLSKSC--SDKLCIRQL--TGITNSLSSTLFEKIYLDYLILQKDDVKRCQVL--QNGVRNGSFVKGESFICNERNLCNWTPTSSD Plicr1 QKVATAAHELY-TSLGFKPPAGQYTILACFALAIKIISLSTGAKCL--PLVRFGNALHDSHAEVLARRGAVRWFLEDRVRLHL-YISTVPCGDASMRFLRGRDNYGVLRTKPGRADSPPTICMSC--SDKIAKWNV--LGIQGALGSQCLSPIYVDGIVIGEEDCERAEVV--INGWKRGVSPKHWPQSSKAKRTLGWVKSGLQ Polpo DRIARLSIDHY-EKKKGKPNEKEWTVIASIVAKMTVLSIGTGNRCV--GKQSMGDVINDSHAEIICKRSFQRYLYNDNVSIHF-YVNQTPCGDCSIYPTLDGSEYGILRIKPGRGD--PTLSMSC--SDKIARWNI--LGIQGSLLSHFVEPIYLSSITITDDSCKRANINNNNNNNNCNSSNDNTT----SKKQLSPIS-SGF Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 DDVASAALQAF-SLQSFAPPSGQFTILASFVLQIKAISLGTGTKCL--PTARYGEALRDSHAEVLARRGAVRWLLESGASLNL-YISTPPCGDASMRYLRGRDNYGALRTKPGRADSPPTACMSC--SDKIAAWNV--LGVQGALGSSLYRPVYLERVVIGGEDCQRAEVL--INGMRRGVPPKHRPMLSKAKAMLGWVVSGKE Rhior3 -----------------------------------------------------------------------------------------------MSALRGRFEFGILRTKP-------------------------------ALLSHLYHPIYLESITIGDHALERAEVF--VNGQKQGAPKNKR------------------ Rhoto1 EVVTRAALSCY-AAANGKPRRREWTVLAAVVLQARCVSIGTGLKAL--PHARLGDVLHDSHAEVVARRGFKRWMYRSEWQVAM-YISTLPCGDASTFFLRGRVAYSILRTKPGRADSPPTTSHSC--SDKLALWAL--LGMQGGLLSALGEKVKLSLVVVGGEEVRRAEGI--NNGIRQGASNKRRSRLSKLKSLVGWLVSGQP Rozal11 DQIKKT------KKKQGN------NILAAFLVNISVVSLGVGHTCL--PDSIIDDVLHDHHAEILAKRGLVRFLVDEKLDSSIDYLSLILQGAASMEKFRGRSSWQSLRTKPGRVDSPFSSCMSC--SDKIGLWNL--LGIQSELLYPLTGPIFVDHIVIGC------EIT-TSIGRKLGAAKKQRSRLCRGKALIHWLIRDSS Sacce1 EEISTRVINEY-SKSACRPIIREWTILAGVAAKIEILSIATGVKAL--PDSELGKILHDCHAEILALRGANTVLLNENWELAL-YISRLPCGDASMSFLRGRLNFNVVRTKPGRYDSNITLSKSC--SDKLLMKQR--SSVLNCLNYELFKPVFLKYIVIPNHHLEQSEAI--LNGVRNGFYTKSQSQVSRKRSQLGWIPTRTD Salro DEVARCALETY-KKRQGKPKADEWTVMAAIVLTMKTVALATGSKCI--GIELLGDIVIDAHAEVLARRAFQWYLTQDNCSLHL-YVSHAPCGDASIFEVLPGVQYGTLRTKPGRGP--PSHSMSC--SDKILRWTY--LGLQGALLPAVLQPVVLSSIVVGEEALTRAEVL--VKGIKQGASRKKRSAVCKLKQHMHWRGNAAA Schco3 DLEVRSVFEVY-SSTGYKPSNAQFTILAAFFLEIKIISLGTGTKCL--PTSQLGEALHDSHAEIIARRGAIRWFLEEGVHVGL-YISTLPCGDASTRFLRGRDNYGVLRTKPGRADAPPTMSMSC--SDKIAAWSV--LGFQGALASLVLKPIHIDHIVVGDEDCERAEII--VNGTRRGVPPRHIPRISQAKSQLGWQRSDPT Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ----------Y---------------------------------------------FYNGNGPTLVARNERGKL---GVALHL-YISQTPCGDASIF----------------------------------------------------------------------------------------------------------- Spipu1 ------------------------------------------MKGL--PSILVGQ---------------------KGISFHM-YISQSACGDASMAALRGRADFGVLRTKPGRVDAEPTLSMSC--SDKIAMWNV--LGLGGALLSHFVEPLYLESIVVGDEAMERAEAI--TNGRRQGFAAKARSPICKAKAALSWVVNPAE Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 DQIVLATFASY-AALSFRPQPTKFTILASFVLRIQVMSLGTGSKCL--PRDKLGDALHDSHAEVLARRSAIRWLAQDGVKLVL-YVSTVPCGDASTRLLRGRDDYGVLRTKPGRADAPPVLSMTC--SDKIARWNV--LGMQGALMSRLFEPVYVDGIVIGEEDCRRAEVL--INGLRRGVAPKHWPLTSKARKALGWLVSGAR Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ---AAVC-AAY-DERKGKPS-GEWTVLAGWAVEVTVLAMGTGTKCL--PPGRMGGSLVDAHAEVAAKRALQAALID-QQYVHL-YVSQTPCGDASIF--EPGTGYGLLRTKPGRGE--PSQSMSC--SDKIARWVA--LGMQGTLLGSLVAPIRLSSIVVGEQALERA------RRRERAATGSR------ERAAV-------- Treme1 DQIVIASLNVY-DKQHGKPINREWTILSSICLRVLPVSIGTGVKCL--SFDKLGDIIHDSHAEILARRGFMRWLVLDGVEVWM-YVSALPCGDASTLHTRGRNGYGTLRTKPGRADSIPTISMSC--SDKMASWCI--LGLQGALLSSLFQPVYIDHVVVGGAEVERAEVL--VNGSRQGAIWRSRSRICKAKKILGWLVSGES Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 DAIADACLNQY-QANSGKPSVKEWTILAGICLQISVVALGTGLKCL--PLSKLGDAVQDSHAEVITRRGFIKYLLDSSYTFHM-YISQAPCGDASMTELRGRVGYGILRTKPGRVDSEPTLSMSC--SDKLARWNV--LGLQSALLAMIIDPVYLDSVIVNQQALQRAEVI--VNGRRQGAP--KSPSATNAKSALDWVQTPED Ustma22 ELIAHLALSAY-HQRGGKPGIKEWTVLAAFILQYTLISLATGLKCL--PFTLLGDVLHDQHAEVLARRGARSWLLHQGVRLHL-YVSTLPCGDASSKLLRGRASSS-LRTKPGRPDSPPSISMSC--SDKIALCNAPGIGMQGSLLSSLMEPIYIHSLTMCDQALKHVENL--ASGTKMGAPTRRRSWLCRRKAELAWLRTPVA Walse1 VDIVDAVLNTY-RKKRAHPGVREWSILAGFVIIFECVAIGIGVKCL--SAIKIGDMVHDCHAEILAKRAFIRYLLNEGVKLHM-YISALPCGDASMIYTRGRMNYGAIRTKPGRADASSTSSLSC--SDKLATLCL--LGVQGGLLANIIDPIYIDKIIIGGSECHRAEIV--VSGLKNGNFKRKRSRLCKVKGAIGWIITDKK Zygro1 NRIAQKVLEGY-RKSSCKPGTREWTVLAGIVADLRLISIATGVKAL--PDAFLGKMVHDCHAEILALRAFNAVILDDNWELAI-YISTLPCGDASMDLLRGRFNYQVVRTKPGRFDSQITLCKSC--SDKLCQRQV--ISILNCMTWKLLKPVYLKYLVTPN-LLHQSQAL--LNGLKNGFYTKGEPAVSRDRNALGWISTSRD [Cluster3162.fasta_al_trimmed; alignment length = 80] Allma1 -------------------------------------------------------------------------------- Ashgo11 LEELKEA-FVPEDVEEEDEDEEEEAGDQLDELREECRNAADAKPLVHHYMECVERVEDCVEEFLQHHLDCAAPKLFDKLK Aspfu1 FSDMISS-L-SEESGEEEEEEEEEVVDIKPKLEEECANGPQCAPYKHHYDECVERVEDCVEEFLAHCATCAAPKLWKALK Aurde31 LSELLSA-IFPEEAKEGAEDEEEEPEDRHPAIREACQESKQCASATQHFKHCQEKVETCVEELITGSVDCAAPKLFAELK Batde5 ------------------MDEKAGVEDPKPIIEEECAESHHCHPFKNLFDSCTARVETCVEEFLM-----ATPKIFAKLH Botbo1 LTSFFSS-FLPEEKEEEEEEEEEEPEDIAPAIRDECAASPACAAATKHFQHCNEKVEDCVEEL---CTSLIWPGYRQEYS Botci1 WSDLVSA-ATPPDKRAEEEEEEEEMVDPKDKIEEECKESAACAPSKHHYDECVERVEDCVEEFLAHCATCAAPKLWNTLK Caeel -------------------------------------------------------------------------------- Canalb1 FRDLLES-VVPEDAPEEDDEEEEETADPLDTLREECTKTAACKPFDHHFHECIERVEDCIEEFLQHCVNCVAPRLFNRLK Cangl LEELKET-IVPEDPVEEDEDEEEGV-DQLDALREECKNTEEGKHLVHHYMECVERVEDCVEEFLQHYLDCAAPRLFDKLK Capow -------------------------------------------------------------------------------- Catan2 -------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------- CocheC53 FTDVWET-FSHEESGEDEDEEEEEEPDPKDKLEKECAESKECHGPKHHYDECAQRVEDCVEEFLAHCATCAAPKLFAQLK Coere1 -MGFFES-INPEEKDEEDEDEEEEPEDPAVPIREVCSKTMTSKALYHHYEECAARVESCAEEFFMHEVDCAADKIFKALK Conco1 ---MAAE-ILDEEPEQEEEEEEEEPEDQKPAIMEACSETKECAPAKHHWQECEERVETCVEEFYMHCVDCAAPKLFSELK Conpu1 FSSFFSS-FLPEEKEEAEEEEEEEPEDPQPEIREECKATSKCAPLTKHFEHCQEKVEDCVEELMMHCVDCAAPRLFSKLR Copci LASFFSS-LVS-----EQEEEEEEPEDVHPAIREECKEQ-KCAQLAKHFEACQEKVEDCVEEILTHPFPLGAPRFLRRTL Croqu1 IGTVLGH-LVPEEEK-AEEEEEDEPEDPSPAIRDECAET-KCSKYKHHFDHCQERVEDCVEELLMHCVDCAVPKVFSKLV CryneH991 FSSFVSY-FVPEEKEEEEEEEEEDPEDIAPAIREECEKN-SCAEHVHHFAHCQEKVEDCVEEFVLHCVDCAAPKIFKKLA Crypa2 -------------------------------------------------------------------------------- Debha1 LKDLIES-AFPESTEEDEDEDEEEIVDPLDTLREECTNTETCKPHLHHFEECIERVEDCVEEFLQHCVNCVAPRLFNKLK Dekbr2 VRDFIEA-MAPEDVKEDDDEDEDEAVDPLDALKEECQKTAECAKSVKEFQACTERVEDCVEEFLQQCVNCAAPKLFSHLK Dicdi -------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------- Fomme1 FSTFWSS-LVPEQKEESEEDEEEEPEDPMVTLREECKESGACVKFSQHFEHCREKVEDCVEEMMMHCVDCVAPKLFAKLV Fusgr1 FTDIVEA-VTPESKTEEDEDDEEELVDQKETLEEECKNAPQCAPAKHHFDECVERVEDCVEEFLAHCATCAAPKLWSQLK Galma1 IASFFSS-FISEAPADKEEEEEEEPEDEQPTLREECKASAKCAALTKHFEHCQEKVEDCVEELIAR---RGKP------- Ganpr1 ----MSD---------------EEVPDPLPVLREECEH--HCTAFKAVYDACAERIQNCALEFLLECIDCAAPKLAKHFV Gloin1 TTTKETS-IIP-----NTEETPEEPEDPKPKIVEECGETSACKPLKHHLEECTRRVENCAEEFFMHCVDCAAPKIFAVLK Hisca1 FTDLISS-L-PEDAAPEEEAEEEEVEDIKPKLEEECANSSKCAPAKHHFNECVERVEDCVEEFLQHCATCAAPKLFRALK Klula1 LEELKDA-FVP-DVEE-DEDEEEEQGDQLDALREECKSTEEGKHLVHHYLECVERVEDCVEEFLAHFVDCAAPKLFDYLK Lacbi2 ISAFFSS-FISEAEVEAE-QEEEEPEDLHPVIREECKESSKCAALAKHFEHCQEKVEDCVEELMMHCVDCAAPKLFSKLR Lenti61 LSALFSS-VFSEDKEPEE-EEEEEPEDILPALQEECQESAKCAPLTKHFAHCEEKVEDCVEEFLAL-------------- Malgl1 -------------------------------------------------------------------------------- Mellp23 ISSVLDN-ILPEKEE-EEEEEEEEPEDPAPAIRDECTET-KCAKYKHHFDHCQEKVEDCVEEMLMHCVDCAVPKVFSKLV Mnele -------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------- Morel2 L-SFITD-LFP-EKHEVAEEEEEEPEDIKPEIEEACGETSACAPLKHHLEECTKRVEDCIEELFLHCVNCAVPKYFNKLV Mucci2 LSDFFSS-FMPEEVVEEEEEEEEEPEDPKPAIWEVC--TEECSALKHHLDECNERVENCIEEFFMHCADCAAPKIMAATK Mydma -------------------------------------------------------------------------------- Neucr2 VTDLIDA-ATPEETTAEEEEDEDEIVDPKETLEEECRNSKECAPAKHHYDECAARVEDCVEEFLVHCATCAAPKLWNTLK Orpsp11 -------------------------------------------------------------------------------- Pench1 -----------EESAEEEEEEEEEPEDPKPKLEEECAHSAVCAPYKHHYDECVERVEDCVEEFLTHCVTCAAPKLWRELK Phybl2 LSDFLSS-LMPEE-VEEEEEEEEEPEDPKEAIMEEC--AQECSSLKKHLDECNERVENCIEEFFMHCADCAAPKIFAATK Picst3 LRDLIEA-VVPEEAEEDEDEDDDEVEDPLVALTEECAATPACKPYNHHFHECVERVEDCIEEFLQHCINCVAPRLFHKLK Plicr1 LSSFFSS-FMPEEKEEAEAEEEEEPEDAHPSIREECQQSAKCAQFTKHFEHCQEKVEDCVEEMMMHCADCAAPKLFSKLR Polpo -------------------------------------------------------------------------------- Pucgr2 ASAITQY-FTPEEKEGEEEEEEDEPEDPAPAIREECTES-KCSKYKRHFDHCQERVEDCVEELLMHCVDCATPQVFSKLV Punst1 LTDLLSS-FLGAEEDKAE-EEEEEPEDIHPGLREECQQSAKCAPLTQHFLHCQEKVEDCVEELMMHCVDCVAPKLFSKLK Rhior3 LSEFFST-FVPEQPVEEEEEEEEEPEDPKEAIMEAC--AEECSALKKHFDECNERVENCVEEFFMHCADCAAPKIFAATK Rhoto1 LSSLFES-FFPQQHKDEESEDEEDPEDQAEAIREACGNTKVCKEFKHHLEECGERLETCVEELYMHCVDCAAPKIFAALK Rozal11 -------------------------------------------------------------------------------- Sacce1 WEQLKIT-VVPEEKEEEDEEEEEEVTDQLEDLREHFKNTEEGKALVHHYEECAERVEDCVEEFLQHYLDATAPRLFDKLK Salro -------------------------------------------------------------------------------- Schco3 ITDFFSS-LLPEPAEEEEEEEEEEPEDSHPVIREECK-EQKCAALAKHFEHCQEKVEDCVEELMMHCIDCAAPKLFSQLK Schpo1 WKNLFTSAFTPEEKKEEEEEEEEEITDPLEKMTQECMDAPDCKEVKHHFEECTARVEDCIEEFLYHCARCADPKVFKVLV Sorma VTEIIDA-ATPEETTAEEEEDEDEIVDPKETLEEECRNSKECAPAKHHYDECVARVEDCVEEFLAHCATCAAPKLWNVLK Sphar -----------EEEEEEEEVEEEDPEDVKEALDEECGEA-ACAKYKAKLDSCTARVETCTEEFFMHCVDCTAPKLFAQLK Spipu1 -------------------------------------------------------------------------------- Sporo1 LSSFFES-FLPAQEKEEEEEEEEEVEDQAEAIREACGQTKVCANFKHHFEECGERIETCVEELYMHCVDCAAPKIFAALK Stehi1 LSSFFSS-FVGEENKKKEEEEEEEPEDLMPAIRSECEESAACKPAKHHFLHCQEKIETCVEEMLMHCADCLAPKLFSKLA Tapde11 MSSALTW-IADEEEEEEEEEEEEEAEDQKPAIVEACESSKACAPLKHHFDECQERVENCVEEMLMHCVDCMAPKLFAQLK Thetr MDDASGS----EDADDDDDDDDDEPEDQKPFIEEACKDK-HCQKALKIYEDCAARLHDCVGYYLKRCIDCAAPQIFAQLV Treme1 LTSIASF-FLPEEKEEEEEEEEEEPEDPAPAIRADCQDS-ECAAPAKHFMHCQEKVEDCVEELLMHCVDCAAPKVFKKLA Trire2 FSEIVEA-VTPEAKVEEEEEDEDEIKDPKEELEEECKNSPQCSPAKHHFDECVERVEDCVEEFLAHCATCAAPKLWSKLK Umbra1 LADLLSS-LLPEQ-HE-EEVEEEEPEDPKEAIMEECGNSKECASLKHHLEECAERVEDCIEEFFMHCADCAAPKVFEATV Ustma22 VSSFFSS-LLPEKESEEEDEDEDEPEDPAPAIYEECEKSKSCAPLKHHFDECSKRVENCIEEFLAHCAQCTAPKLFAKLV Walse1 LTDYINS-AIDEQEEQEEEEEEDEPEDIYPAIREECENSSHIAHLKHHFEHCNEKVETCAEEIFLHAVDCSAPKLFTKLV Zygro1 LEELKES-FTPEGGEEEEDEDEEEGGDPLDSLRDECANTPEGKELTHHFMECVERVEDCVEEFLTHYVDCAAPRLFSKLK [Cluster3165.fasta_al_trimmed; alignment length = 97] Allma1 ------------------------------------------------------------------------------------------------- Ashgo11 K-HHDLVADLQLRAFLDFFANFARVGYYLGIPMTGPKPLPTRRERWTVIRAPFAHAKSKENFERHTHKRLLRLWDANPEVVEMFLSYITKHGVGMKC Aspfu1 E-FGLPVCDLQLRSYLEFFADFARAAYYLELPVSGPVPLPRIVERWTFPRSNFVHKKSQENFERITLRRLIQIKDGHPQAVQAWLAFLRKHGVGMKA Aurde31 S-HGIPVAVVHFRSHLELYTHFVHAASALGIPCGRPAKLPNQRSLWTVPRSPFIYKKSQQNFHRITHKRAIKLWDANSEVVSFFADYIVRHGVGVRV Batde5 P-YGQLVCNIVLSGYLDFMAYFSYTAKSMNMSVSETIHMKTYTQRWFTNKGPFVHAKTKEIFERKQYYRMVQVFDAHPESVKEWVQYVNKSGIDLK- Botbo1 T-HSIPVALIHLRSPLSLFTHFAHAAYGFGIPISHTATLPTQRSLYTVLKSPFVHKKAQENFERKISKRAIKAWDADGEVVGKWIKYLELHGVGMRV Botci1 ------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------- Canalb1 T-HGDEVATLTIRGYLIRVGEFARTAYYMGIPMSPLMALKTEKRLYTVIKSPFAQAKTKQNFHRVTYKKKLVAYDANPEIIDLWLSYINKNDVEYKA Cangl T-HGHLVADLQLRAYLDFFCDFIRAGYYLGLPMTGPKPLPTRRERWTVIRSPFVHAKSKENFERHTHKRLIRVWDSNPEVVQMLVDYITKNGVGLKC Capow ------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------- CocheC53 E-YGVPTCDLQLRTYLLLFSDFARAAYYMGLCARGPIPLPRITERWVVPRSNFIFKKSQENFERVTMRRLIQIQDGHPDVVKAWLAFLQKHGVGMKA Coere1 ------------------------------------------------------------------------------------------------- Conco1 T-HGVVSCNLHFRSYMDFYIDFARAAHALNIPCSGPIPLKTQIERWAVPKSPFVHKKTQQVFERKTHKRFIQIKDAHPQTLQFLLDYLLEHGLGMRV Conpu1 T-DGVPVATLHVRGHLELFLHFAHAASALGIPCSRPASLPTQRSLWTVPTSPFIYKKSQENFERRVHKRAIKMWDADPEVVDRWVRYIQHHGVGMRI Copci P-YHIPVASLHLRSYLDFFSHFAHAAAALGIPISKTAHLPTQRSLWTVPRSPFAHKKSQENFERRTHKRAIKAWDAAPEVVDRWCDYLRRHGVGLKV Croqu1 ------------------------------------------------------------------------------------------------- CryneH991 T-HGIHVATLHLQAHLDLVSQFAHSAHSLNIPTSLPAFLPREKSLYTVLKSPFVKKKAQENFERRTHKRAIKVYDADREAVDLWLRYLRQNGVGMKA Crypa2 Q-YGVPSCDLQLRSYLESFCDFARAAYYLGLPAYGPIPLPKITERWTVPKSNFIHKKSQENFERITRRRLIQIKDGHPETVQIWLAFLQKHAVGLKA Debha1 T-HGHEVAKIEFKGYLIRASEFARAAFYLGIPCSKVQSLKTEKRLYTVIKSPFAQAKSKENFKRTTYGRKVYAYDATPEVVDLWLSFINKHGVKYNA Dekbr2 E-YGDLKAEVIFKCYLEFFCNFARVAYYLGIPATGPKPLPVRRERWTVIRAPFVHAKSKENFERRTYTRMLRLWDANERVVDTFLAYIKENGVGVKV Dicdi ------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------- Falba TFSKIRRAQINLSGYVDTFAVFIQTAMIMKIPVSGLIRMPTQRKLFSVIRSPFKYNRSHAQFGMTTHKRLIQVHNCTDEVLNHFLRYLYVRGIGMRM Fomme1 T-HGIPVASLHVRGYLDLFLHFAHAASALAIPVSEPIRLPTQRSLWTVPKGPFVHKKAQENFERKVHKRMLQAWDATDNVVEHWLRYIQTYGVGLRI Fusgr1 E-HGIPSCDLQLRSFLEFFSDFARAAYYLGLPAYGPVPLPRITERWTVPRDNFIFKKSQENFERKTLRRLIQIRDGNPETVQLWLAYLRKHGVGMKA Galma1 T-HDIPVANIHFRSHLNLFTHFAHAASSLGIPTSKVVPLPTQRTLWTVLRSPFVHKKSQENFERKVHKRAVKAWDADPEVVGRWVTYLRAHGVGMKV Ganpr1 --NPILTARLTLTAALRLMAHFAHAAAHLNLRTAPGTWVRPNLRRFRILKSPFVHAKSKEIFERRVHAMTVDVHNGHWETQRAWVDYVVAAGIKVTL Gloin1 K-HNITVCNIHFRSYMDFFVDFARTAFHLSIPCSGVVYLPTQTTRWTVPRGPFVHKKSQENFERKTHKRLLTFKDANKNVIDKLLLYLSKNGIGMRV Hisca1 E-FGLPVCDLQLRSYVEFFADFARAAYYLNLPAFGPTPLPRITERWTVLKSNFAHKKSQENFERVTLRRLIQIKDGHPDVVQTWLAFLRKHGVGMKA Klula1 T-HRDLIADIQLRSYLDFFSSFVRAGYYLGIPMKGPKPLPTKRKRWTVIRAPFVMAKSKENFERHTHARLIRLYDCNTELVETLLSYISKHGVGIKC Lacbi2 T-HGIPVASVHFRSHLEFFTHFAHAASSLGIPISKVARLPTQRTLWTVPRSPFAHKKSQENFDRRVHKRAIKAWDADPEVVDRWLMYLRKHGVGMRV Lenti61 T-HGIPAATLHFRSYLDFFVHFAHAASALGVPLSKPVHLPTQRRLWTVLRGPFVHKKSQENFERRTHKRVVKAWDAHPDVVDMLVQYLEKHGVGMRA Malgl1 T-HGVHVATLQLTSNLDFFADFARAAHALQIPTGGIAMLPIRTTLWTVPRGPFVHKKSQENFWRRVHRRSIKVYDASDITVDRWLHFLRAHGVASKA Mellp23 ------------------------------------------------------------------------------------------------- Mnele ------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------- Morel2 T-HNITVAHLHLRSYLEFFTDFARAAAALEMPCSGAIPLPVQTSKWTVNKSPFVHKKAQETFERKTHKRLLAIKDTHPDVVRRWVQFLNQNGVGMKV Mucci2 T-HDIPVCNLQMRGYLDFFADFARAAFHMGMPCSGTVPLPTQTSRWTVIRSPFVHKKSQENFERKTHKRLLQIKDAHPDVVERWLRYLTMNGIGMRA Mydma ------------------------------------------------------------------------------------------------- Neucr2 E-YGVPSCDLQLRSYLEFFCDFARAAYYLGLPAFGPVPLPRMIERWTVPKSHFIFKKSQENFERVTLRRLIQIKDGHPETVQLWLAFLQKHGIGMKA Orpsp11 ------------------------------------------------------------------------------------------------- Pench1 E-YGLPVCDLQLRSYVEFFADFARAAYYLNLPVSGPVPLPRIVERWTVPRSNFVHKKSQENFERITLRRLVQIKDGNPQAVQAWLAFLRKHGVGMKA Phybl2 T-HGIPVCNLHLRGYLDFYADFARAAFHLGMPCSGTVPLPTQTSRWTVIRSPFVHKKSQENFERKTHKRLLQIKDAHPEAVDRWLRYLTRNGVGLRA Picst3 T-HGHEVAKIKFRGYLIRAGEFARSAYYLGIPTSKLTTKKTEKRLYTVIKSPFAQAKTKQNFHRTTFNKELVAYDANPEILDLWLSFINKYDVSYKA Plicr1 P-HGVPVAQLHIRSFLDFFAHFAHAAAALGIPITRPAMLPTQRRLWTLMRSPFVHKKSQENFERKVHKRVIKAYDADREVVDRWVRYIRQHSVGMRV Polpo ------------------------------------------------------------------------------------------------- Pucgr2 ------------------------------------------------------------------------------------------------- Punst1 ------------------------------------------------------------------------------------------------- Rhior3 T-HDIPVCNLQFRGYLDFYADFARAAYHLGMPCSGTIPLPTQTSRWTVIKSPFVHKKSQENFERKTHKRLLQIKDAHPEVVDRWLKYLTMNGVGLRA Rhoto1 T-HGVHVGTLHLRSYLTFFTNFARAARALGLPTSGATYLPTRVWLRTVVRSPFAHKKSQQNFWRRTHKRAIKVYDGDERIVQAWFAYLSSQGVGMKA Rozal11 ---------VKVRSFANTFTEFIQTSENMGLAVN-VVPNRYTVQRWIVLSSPFKYKTARTWLERRVHGNVLHIYNASKENADRMIWYLKLN------ Sacce1 K-YGDLVADIQLRSYLDFYSDFIRTGYYLGIPLTGPKPLPTRRERWTVIKSPFVHAKSKENFERHTHKRLIRAWDTNPEVLQMLIAYITKHGVGMKC Salro ------------------------------------------------------------------------------------------------- Schco3 P-YRVPVASIQFAGHLELFTHFAHAAYSLGIPCSRPARLPTQRSMWTVIKSPFVHKKSQENFERKTHKRVIKAWDADGEVVRRWAAYLRKHGVGMRV Schpo1 SENDVLCASLKIKSFLDTFTDFIRTAYYMKIPIKGPRPLPNKVESWTLLRSPFIHKSSQENFERITHSRLIQLYSVNPVTLETFFSYLRKCDLKLQA Sorma E-YGVPSCDLQLRSYLEFFCDFARAAYYLGLPAFGPVPLPRMIERWTVPKSHFIFKKSQENFERVTLRRLIQIKDGHPETVQLWLAFLQKHGIGMKA Sphar ------------------------------------------------------------------------------------------------- Spipu1 PTHHALACTLHLQGYLDFVAHFCHSAHAMQMPCSETIHLPVQTKKWYVIKGPFVHAKTKEVFEQKKYVRALQVFDASEESVKEWIAYIVKNGVDVHV Sporo1 --HGVHVATLHLRSYLQFFTSFARAAKALGLPTSGSVALPTRTSLFTVPRSPFAHKKSQQNFWRKEHKRAIKVFDGNEEVVNAWLAYLRKEGVGMKA Stehi1 --------MIHLRSYFPFFCHFIHAAASLGIPVSGTATLPNRKSLWTVIKAPFVFKKSQENFQRIVHSRCIKAYDADPAVVDRWIKYIERHGIGIRV Tapde11 T-HGVPSCQLQLRSYLSFFADFARAAYHLKLPASGPVPMPKKTERWTVPRGPFVHKKTQENFERITYKRMIKIADGHPEVVERWLSYLNSNGVGMKA Thetr ------------------------------------------------------------------------------------------------- Treme1 ------IATLTLSSSLDLFSQFASSANSLSLLTSITP-LPTTKELHTVLKSPFVMKKAQENFMRKTHKRMIKVWNGDRVVVDLWSRYLKEGGVGM-- Trire2 E-YGIPSCDLQLRSFLQFFSDFARAAYYLGLPASGPVTLPRITERWTVPRSHFIFKKSQENFERVTLRRLIQIKDGNPETVQLWLAYLRKHGIGMKA Umbra1 T-HGIPVCNLHFRGYLDFYVDFARAAFALKMPCSGPVYLPTQTSRWTVIKSPFVHKKSQENFERKTHKRLLQIKDTNPEVVQRWLHYLKMNGIGMRA Ustma22 T-HGIHVATLHLRSYLELFADFARAAFAIGIAASGVASLPIRTSLWTVPRSPFVHKKSQENFWRKTHSRAIKLYDANDQVVDRWLHFLRIHGVGQKA Walse1 S-HNIPIANLQLKAYLDFFADFARAAYHLGIVLTGPAMLPTRHERFAVLKSPFVHKKSQEVFERRTHTRLLKVWDSDDQVVQLWIQYLNQHGVRMK- Zygro1 Q-YGDLVADLQLRSYLDFFADFIRTGFYLGMPLTGPKPFPTRRERWTVIRSPFVHAKSKENFERHTHKRLIRVWDSNPEVVQMWLSYITKHGVGAKC [Cluster3168.fasta_al_trimmed; alignment length = 85] Allma1 ------------------------------------------------------------------------------------- Ashgo11 KD-KRGNKEQLQRANYLLQLAALHTMYLGTLDLIQKKTKIALTPALKRTVCKCRRLLVPYRTVTSRVQNESRLVQTCL-CAKRFP Aspfu1 ------------------------------------------------------------------------------------- Aurde31 KQ-RQQNRDTLQRLNFLLQASTYLASYAQDIRAVGSRTVTRIDPAVKRAICKCGTVLIPGSTSQVRILPSSTTRTKCTACTRVIP Batde5 KQ-ADQHLDCMHRLNFLYQAAHLYTSFGHQMKHVAKKLVVRLDPHVKRTICKCHGALVPGISSTVRLDDT-SVDITCLYCVRTLG Botbo1 KGGSETNRDLLQRLNFLYQASVYLQQYAGSMKAIGAKAIVKMDPVVKRTMCKCNTILVPGTTASVRVKPSSSISYTCTKCSRVIP Botci1 ------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------- Canalb1 KG-KGPNRDNYARISYLYQISNQFYLYNRNLDLIAKKTVIKLSPHIKRTLCKCNTMLIPGLTMSMYIENLSKFVNKCLNCCKRFP Cangl KKGKGGGREHFQRVNYLAQLSRHVAQYNRNLVQVSHKTKTRLSPSLKRSMCKCKIAQIPTITTKVSV---EKLAIECQ-CVKRFP Capow QQQQQANREGHERINFLYQAAHLVLQLLKTLKGVRQRLVLRVDHTIKRTVCKCSALLIPALTSSVRLQSASKIVVKCTSCSRRY- Catan2 ------------------------------------------------------------------------------------- Cioin KKG-NQKKDVYQRLNYLYQAAHFAISYTRTMKTLAQKNVVRLHPHVKRTICKCDLLLIPGVTCTSRN--KGKTVVTCQGCFRRY- CocheC53 K----PNKHLHARSSFLYQAATYLTLLSSDLQQVSRKGQLRLAVSLKRTLCKCNSILVPGRTATHRIENASKLVITCGVCQKRFP Coere1 -----PNRELYERMNFLYQSSQFFATYTKEMRQMARKSVLRVSPHVKREICKCSTPLMPGVSCTIRIKGKAHVITTCTYCQKRLM Conco1 QKY--RNKEMFSRMNYLYQASHLLQSYIKNMKLIGTKNLNRIDSSVKRSICKCDQILIPGNSCSIEIINETNIQIKCTNCKKQFN Conpu1 KN-QDQNRDILQRLNFLYQASVFLNNYVDAMKVIGQKTIVKMDPSVKRTLCKCNTVLVPGVTARVRVKGSPVVSYTCNACVRRIP Copci KKEREPNRDVLQRLNFMYQASAYLQRYARSIPTVAQRTTLKIDPSVKRTLCKCKTTLIPGVSVATRLRKLSSMVYRCLNCTKRIP Croqu1 KT-TNPNKDVLQRLNFLHQASHYLATLSNTIKPIAKKAVVRMDPSVKRSFCKCSIILIPGQTSKTKIHKSKIISITCLSCKRCIP CryneH991 KQPKQLNKDLFQRINYTYQAAIYLQNGMRETKTMVVHNQLKLDPSLKRSICGCSTVLIPGLTSRIRNRPNRNTNQTCLTCVLSIP Crypa2 -----SNRHIYSRISFLYQAATYLTELLTDLRNVTLKSQVRISPDIKRSICKCDSLLVDGQTSSSAVENRSKLVVKCYTCEKRFP Debha1 KK-QGPHIDNYARISYLYQASSHF-AMARNVNLISKKSVTKLSPALKRTICKCQTLLVPGVNETIEIENKSKLVHSCNTCKKRFP Dekbr2 ------------------------------------------------------------------------------------- Dicdi NNNNNGNSDIYKRINFLYQASTLLKTYNSSMKRMAQKQVIRINPTIKRTICKCCSLLIPGDSSTVRI--EESVVTTCNNCVKRFD Dmel ------------------------------------------------------------------------------------- Enthi KQKKNPLKE--ERMNYLFSISSLMTQCGLSIRNLAHKYVSRISKTWKRKYCTCWMPLTYSSFKTQLI-----IVTHCYWCRRLFY Falba QP---QQRDAVHRINFLEQASRLFLNFGRDLLSVSQRAVLRIDPTLKRSVCKCRAPFDIASTLRVRVRRKSRLITSCKTCSRRMG Fomme1 KN-KDPNRDIIQRLNFLYQASSYLNGYVKSMKIIGQKTNVKMDPSVKRTLCKCNTLLMPGVTAKVRVKPLPSVNYTCMHCSRRIP Fusgr1 -----QNRIIYSRASYLYQAASYL--AVTDLRAVTQKTQIRQSPAMKQAICKCDTLQIEGDTCTSTVENASKLTIKCRTCVKRYP Galma1 KQ-KEANRDIVQRLNFLYQASIYLQSYVQSMRIVGQKTTVKMDPSLKRSLCSCSTTLVAGTTASIRVKSSPTVLYTCLHCTKRIP Ganpr1 -----PSADAYMRMNYLAQIAAWASTYLSTMKTITERLVLRIDPSLKRMTCKCGVLLVPATTASVSVTHTSSITTTCRRCPRRLV Gloin1 -----QHREIYQRMNFLYQAATLMTTYINTMKTIGTKQVLRIDPSIKRTICKCETILLPGVTSKVRI--KSRLQVMCTECSKNY- Hisca1 KA---GQSHLRARIAFLYKASTYLQSLASQMRGVSLKSQLRLPHDIKRSICKCDSLLIPNATCVETVENASRRVVSCNSCIKRFP Klula1 KENKKGNKEHYQRLNYLIQSSAFLATYIKNMDSIRKKNQLALSPHMKRQVCKCQRLLIAGRNLQMKINGSKKLVYQCI-CTKKFP Lacbi2 KQ-KDANRDIIQRLNFMYQASVYLQSYVHALKVVGQKTTVKMDPSIKRTLCKCNVVLVPGSTAFVRVKRSSSVVYTCTGCSRRIP Lenti61 KD-KNANRDIIQRINFLYQASTYLNTYIGSMRIVGQKAMVRMDPSIKRTLCKCDTVLIPGSTASVRVRPLSSVVYICMTCTRRIP Malgl1 ------------------------------------------------------------------------------------- Mellp23 KN-NNPNRDVLQRLNYLHQAAHYFA-MSTSMKAVARKAVVRMDPSVKRSICRCNLLLLPGHTSVVRLRPSKTVSIVCLSCSRTIP Mnele ------------------------------------------------------------------------------------- Monbr KD-KDKDREAYERMSFLFQAA-----YVICMRAIARRLVARLDPTLKRQICQCWVVLVPGITSKQAI-----LRIDCLSCQRRLP Morel2 K---DQNKEIFQRMNFLYQAAMCMATYASTLMEVGRKNVIRIGPTIKRSVCQCEALLIPSISCEVRV--EATTRVICTACFRRY- Mucci2 GKDQKKNVQAFERLSFLHQAALLMSTLNNHMKQITGKLVMRLDPSVKRLVCKCDTPVIPVITSTSRI--KSKVVQTCKICKRRYT Mydma -----PEESH--GVTLPRSMSLCM--YMKSLHGIKSKKVLRWSQDVKHAYCRCHMLLVPGITTRVRI--ANRIVSTCLLC----- Neucr2 G----QNRAIYSRVSFLQQAAVFLSRLATDLRSVSLKTRIRLSPAVKRTICKCDSVLIDGSTCTTVIENRSKLVRRCHACERRYP Orpsp11 KAKNNSLTESNIRMNFLYQASNLLATYSTTLNIVAQKTVSRMDPNVKRSICKCKTPLIPGLTSNIEI---DDYAIECKSCKREFK Pench1 KG-K-SQSHIRARLDYLHQAAAYFQGCVSHLRAVAMKTQIRLPITLKRSVCKCDTILVPGLTCSRETRNASRLVVRCLSCEKRFP Phybl2 KKQGIQQLQTYQRMNFLHQAATLMSTYNSTMKKIGRRMVFRLDPNVKRTICKCDSTLVPGLTSSIHV--TSRVITTCKVCTKKF- Picst3 ------------------------------------------------------------------------------------- Plicr1 KS-KEANRDIIQRLNFLYQASTYLNHYVKTMKVVGQKAIVRMDPAVKRTLCKCNTVLVPGSTANVRVRSSSSVVYTCLSCTRRLP Polpo -----KNIDVYKRMNFLYQAAYLMKQYCNVIKQISRRGVIRMNSRLKKTICKCSSLMVPGVSSTVRIKDH-RITLKCNNCVKRFQ Pucgr2 KS-KRQNGEVLQRLNFLHQAANYLATLSKTMKVISKKAVLRMDPSVKRSICRCHLLLIPGYTSSTRLLRSSSVNVTCSACQRQIP Punst1 KNTKDANRDILQRLNFLYQASVYMNSYVKDMKLVGRKTTVRLDPSVKRTICKCNLVLLPGTTARVRIHASCSIVYTCLSCLRRIP Rhior3 ------------------------------------------------MICKCDTTLLPSITSTHRI--QSSLVTTCKVCKKRYA Rhoto1 KG-RNISRDSLQRLSYLYQASILLNSVAREMKQVAKKATVRMDPAVKRTVCQCATVLVPGVTSTHPD------------------ Rozal11 ------------------------------------------------------------------------------------- Sacce1 KA-HGANQDHFHRLNYLYQISAYQTRYIKSMDLISKKTKTSLLPTIKRTICKCHRLLWTPKKL--EITSD--LSVMCG-CVKRFN Salro -----KNSDAFARINFLMQASALALSYTTHATQIAQKKVLRLHKSMKRSICKCSTLLRPGVTARVRTAPR-RVIVTCLYCMKRFH Schco3 KPAKDANRDLLQRMNFLYQSSAYLNTYIKNMKAVGRKSVMRIDPAVKRTICKCDTVMIPGANVNVRVQSSRNLSYICPTCKRRIP Schpo1 KS-K----DQHARVSYLYQASQLL-FYISTAKDVSQKSVMRIHPDIKRTICKCNSLLVPGKSCSIRFEEPSRVLWICKKCKKR-- Sorma G----QNRAIYSRVSFLQQATVFLSQLATDLRSVSLKTRIRLSPAVKRTICKCDSVLIDGSTCTTSIENRSKMVRRCHACERRYP Sphar ------------------------------------------------------------------------------------- Spipu1 QQ-KGEHKEAFQRMNFLYQAAVLMASYAHTLRQVERKLVLRSHPYVKRTMCKCEGILLCGVTASVRTSARGKIQTVCKECAKSLP Sporo1 ------------------------------------------------------------------------------------- Stehi1 KN-KDANRDILHRLNFLYQASAYLDSYVRSMKQIGEKTTVKMDPTIKRSLCKCDSVLIIGLTASCRVNHSKYVITMCYRCRRRIP Tapde11 ------------------------------------------------------------------------------------- Thetr E----PKRQK--GLDGTPKPSLAQPAYVGNIRELARRLVLRLDRSISRQLCKCDIILVPHISAKVRI--A-KVTTTCLSC----- Treme1 KHIESPQKDSYDRLTFTLQASLYLQAKLGFIMGL--RLIVR-DPGLKRNICKCGTVLIPGLTLKVRNQIANKTTHTCLFCQRSIP Trire2 -----QNRHIYTRASYLYQAAVYLANVVSDMRSVSLKAQIRQSPSIKQTICKCDAVLIEGKTCHSSVENPSKLVIRCDTCVKRYP Umbra1 KSDPSDNLQIYQHMNFLHQAAILLSSYCNTMKNISKKLVLRLDPNVKRSICKCDNVLIPSVTSDVRV--KSRTAITCKSCQRRL- Ustma22 ------------------------------------------------------------------------------------- Walse1 ------------------------------------------------------------------------------------- Zygro1 GS-NRGNKEHYQRMNYLYQLAMWNTMYAKNMDLVSKRTRAEMLPQLKRTICKCHRVLVPKKTM--RVQTDS-LQLVCS-CVRNFP [Cluster3175.fasta_al_trimmed; alignment length = 120] Allma1 TEFTPIDSDPTFGRVMRFLRLEDYGLWAASTAAAPATYLKAAAALGFVGGFFLAYQQSSFRFWGVSENQREIEKRAAGKEHH-LGKSSLLQGVSARHSRYTALSFSWLPWFNFGVNWDLY Ashgo11 ------------------------------------------------------------------------------------------------------------------------ Aspfu1 -----------------------------MAAASPLAFMRLATAIGLIGGLHILYQRSCNRFYGFTENAREVEMVKKGEPLY--GTSQVLQGVAARNSRYSQLFIHVLPWFNIGVDTAKY Aurde31 PPHPLIDSDPFAGRVVRYFRPSDYAYWAGFTAGVPALLMRLGGVLGFMTGFLFAYQRSSYRFWGWTENQREQELARKGLPLY--GTSGEIQNVAFRNSQYSQLFFHAVPWFNLGVDTAKY Batde5 IPYPFITDEPDLKTMARYFRTSDYVAMTGFATVFPGAL------------------------------------S--------------------------------------------- Botbo1 TPFPLIDADPHATRVVRYMRPSDYAVMAGATGAAPAALLKLATFIGFAGGFLLAYQRSSFRFWGWSENEREQAKAKEGKPLY--GETDIVQGVAHRNSAFSQLKFGAIPWFNFGTDPAKY Botci1 TE--------HIKRVLGYARPSDYAVGAATATAGPGLMMRLSGVIGAGAGFFMFYQRSILRFYGFTENKREQEMVKKGESLY--GESSTIQGVASRNSRYAGVWMHVMPWFNMGVDTAKY Caeel ------------------------------------------------------------------------------------------------------------------------ Canalb1 SDYELIDGDPYFTRVVSYFRFSDYVNWAVITASFPLGMLRVSTLLGFFGGFCLNYVKSSQRFLGWRENSREVKLLSQGVLPYNEHLSKLNKDISNRNSQYSHALLFVIPWFNTQVDLKKY Cangl ------------------------------------------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------------------------------------------ Catan2 GEFPIIDTDPHASRVVRFFRPSDLGVWAALTAAGPAGYVRSMGAVGFIGGFLLAYQRSSFRFWGLSENSREIEKRAEGKPHH-LGESDLLQGVAARHSRYTALKFSWLPWFNFCVNWDLY Cioin ------------------------------------------------------------------------------------------------------------------------ CocheC53 GEYPLIDNDPHISRVMRYTRPSDWAYGAALGSLSPGLMLRLTGAVGVAGCFMFAYSRSCMRFYGARENRREVEMVKKGEPLY--GKSEMMQGVAHRNSRFAATFGHVLPWPNLGVDTAKY Coere1 SDYPVIDTDPIFSRVVRYMRPLDYTVWAATTASGPAFIMKIVGAFAFIGGFLTAYQMSSARFFGISENAREIRKKSEGKPMH--GQSSLIQRISSSYSTGAFLNFDVIPIFNFSHSKGVI Conco1 TPYPPIDLDPEFGRVVRYFRGEDYASWAGLTAAFPGAYLIMCGILGTMAGFFYAYQSSSMRFWGWTENEREQKKAQQGLPLY--GESQLYQQTAANNSRYAALKLSTLPWFNFGVDTSKY Conpu1 TPYPLIDADPHASRVVRYMRPSDYATWAAGTAGFPAALLRLGGLLGFIGGFMLAYQRSSFRFWGFTENRREQEKAQAGKPLY--GESTQVQDIAYRNSAWSQLKFNMFPMFNFGTDPAKY Copci SPYPRIDSDPHFSRVVRYFRPSDYAVWAGTTAAVPAALMRLGGLVGFIGGFLFAYQRSSVRFWGWSENKREEEMAREGKPLY--GESHQIQEMAARNSTFSQLKLSAIPMFNLGTDPAKY Croqu1 HAYPVLDTDPHFKRVMSYLRGSDLATWAGLTAIVPAVLYGLGGWLGFCGGFLMVYQKSCNRFLGWTENQREQELARSGKSIW--GESTLIQSTAHHNSQFAHMKFSTIPWFNFGVDVSKY CryneH991 RPYPLIDSDPHFSRVVRYMRPNDYALWAGAAAAGPGLLLRLTGFLGFFGGFLLAYQQSTFRFWGWRENAAEVQKAKEGKPLY--GESQLLQGVAARNSTWSQLKLHAFPWFNVGVDPSKY Crypa2 TDYPLIDNDPHFKRVIGYARPSDYAFGATAAAAGPGLLMRLAGAIGICGGFLAFYNRSILRFYGFTENAREVEMVKRGEPLY--GVSKLMQGVAARQSRFSSLFSDVVPWFNFGVDTAKY Debha1 SDYELIDVDPHFKRVISYFRPSDYGCWAATMAGFPLALLRAASLLGFCGGFFLAYVRSSRRFLGWSENAREVKKLSEEKLPYHENESVLMKDIANRNSQFSFTVMAIIPWFNLGVSIQKY Dekbr2 AKYEVIDEDPKFGKVVRYFRPADYALWGGSAAGAPLLLVRAAGLIGVIGGFILAYNESTKRFWGLSENKREVQKLSQGKNPYGVEKSSLLQDVASRNSNHSQLLLSMIPWFNFGVDLKKY Dicdi ------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------ Falba -KYPVVQPNPTFLETTKNIRDSDILKGGAVAAVSMGFLIALSTFLCAVGGFSVAYFESSFRLMGLKLNDLEVAQ---------------------------------------GV----Y Fomme1 TPYPLIDSDPHAFRVVRYFRPSDYATIAAGTAAFPAALLRLGGFLGFLGGFMLAYQRSSFRFWGWSENKREEERAREGKPLY--GESDQVQGVAHNNSAYSQLKLHAFPLFNLGTDPAKY Fusgr1 TDYPLIDNDPHFKRVVGYARTSDYLAGTAAAAFAPAALMRLAGGIGVLGGFLYFYQRSALRFYGATENSREIEMVKKGEPLY--GASRLLQGVAARQSRYSALFLSTIPWFNFGVDTAKY Galma1 TEYPLIDADPHASRVIRYFRPSDYAAWAGTTAAFPAALLKLGGFLGFTAGFLVAYQRSSLRFWGWSENKREEERAREGKPLY--GESPQVQKAASRNSQWSQLNFAIFPMFNFGTDPAKY Ganpr1 TPYPFVTAEPDPITVVRYLRASDYLAFGAIAAGFPSAF-LLQVPMYATLGFAAIYINSLMRFWGWKENAIEAKQPA-----W-------------------------------------- Gloin1 TNYPVIDIDPHFKRVVRYFRPSDYVVWAGVTASGPAFMLKLSTVLGFSAGFLLSYQRSSLRFWGWTENSKEMEKLEKGEPLY--GPEHMNQKASSWFSKYSALKFSSIPWFNFGVDPKKY Hisca1 TDYPVIDTDPHVKRVFGYARPSDYAVGAGVAAISPALFMRLATAIGMFGGLLTVYNTSCKRFYGFTENKREVDMVKKGEPLY--GVSSLMQGVAARNSRYSSLFIHVIPWFNFGVDTAKY Klula1 ------------------------------------------------------------------------------------------------------------------------ Lacbi2 TPYPLIDADPHASRVIRYFRPSDYAVWAGATGAFPAALLRLGGFLGFVSGFLLAYQRSSVRFWGWSENSREEKMAREGKPLY--GESPQVQAAAFRNSQFSQLKFSAFPMFNLGVDTSKY Lenti61 TPFPLIDADPHAGRVIRYMRPSDYAVWAGATGAFPAALLRLGGLLGFVGGFLMAYQRSSFRFWGWSENKREEEKARRGLPLY--GESDQIQGAAYRNSAFSQLKFHIFPMLNLGTDPEKY Malgl1 TEFPLIDSDPHFRRVVRYFRPSDYYAIAGTAVAFPSALLKLSTFLGLCGGFLYAYQRSTFRFWGWTENAREQELDVP---GQ--GKSSLLQGVAHRNSAFSQLNLGTSVLFRV------- Mellp23 HAYPVLDTDPHFKRVMGYLRGSDLATWAGLTAMVPGLLYGIGTWIGFCGGFLMAYQKSCNRFLGWTENEREQELARAGKPIW--GESTLIQSTAHHNSQFAHMKFSTIPWFNFGVDVSKY Mnele ------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------ Morel2 TEFPVIDSDPHFNRVISYMRGSDVVAWGGLTAAAPAALLGLATAMGFMGGFLYSYQKSSLRFWGWEENVREQAMAAAGLPAY--GEPTMAQAAAARNSKFAALKFAAIPWFNTLADTTPN Mucci2 TPYPVIDSDPHFSRVVRYMRPSDYAAWAAGTAAAPALLLRIATVVGAFGGFLYAYQTSSLRFWGWTENSAEVAKAKEGKALY--GESYMVQDASARNSRYSQLKFGAIPWFNFGVDTSKY Mydma ------------------------------------------------------------------------------------------------------------------------ Neucr2 TNYPLIDNDPHFRRVIGYARPSDYVHGTVAGAAGPGLLMRLATAVGFFGGFLYFYQRSILRFYGMSENAREVQMVKAGQPLY--GVSTLVQGMAARQSRYSALFFAVLPWFNFGVDTAKY Orpsp11 ------------------------------------------------------------------------------------------------------------------------ Pench1 TDYPLIDSDPHLKRVFGYARPSDWAVAGGMASAAPISFMRLATAVGLLGGLHILYQRSCQRFYGFTENAREVEMVKKGEPLY--GKSQMLQGMAARNSRYSELFIHVVPWFNFGVDTAKY Phybl2 SAYPVIDTDPHFFRVVRYFRSSDYAAWAAGTAAAPAIMLRVATVFGAFGGFLYAYQNSSLRFWGWTENAAEVQKLKEGKSLY--GESSMVANESSRNSRFAQLKFSVFPWFNFGVDTSKY Picst3 SDYELIDVDPHFLRVVRYFRSLDLGIWAATTAAFPLALLRTATLLGFVGGFYLAYVRSSKRFLGWTENSREVSKLSQEKLPYHENVSVLLKDIANRNSQYSFTAIAILPWFNFGVSIDKY Plicr1 TPYPLIDADPHFTRVVRYFRWTDYATWAGATAAAPAALLKLGAFIGFVGGFLLAYQNSSFRFWGWRENKREEERAAAGLPLY--GESDQVQAAAHRNSAFSQLKFQAIPMFNFGTDPAKY Polpo ------------------------------------------------------------------------------------------------------------------------ Pucgr2 HKFPVLDTDPHFKRVIRYMRSTDLAAWLGFTVGVPGLLYGLGTWLGFCGGFLMAYERGANRFLGWSENEREQKMARSGRPIW--GESTIIQTVAHHNSQFAHLKFSTIPWFNFGVDVSKY Punst1 HQYPLIDQDPHASRVVRYMRPSDYGYWAAGTAGFPGLLMRLGGLFGFVGGFMFAYQRSSMRFWGWTENKREEELLAEGKSLY--GESDQIQGIAARYSTFSQLKFQAFPWFNLGVDPAKY Rhior3 QSYPVIDTDPHFSRVVRYFRPSDYAAWAAGTAAAPALLLRVATIIGAFGGFLYAYQSSSLRFWGWTENAAEVAKAKEGKPLY--GESYMIQDSSARNSRFSQLKFGAIPWFNFGVDTAKY Rhoto1 TPYPVVDADPHFNRVMSYMRPSEYALWAAGTAAFPAAILKIATWLGFAGGFLLAYQTTSLRLWGWRENEREQVRAKEGKPLY--GESDLIQGVAHRNSLWSQIRFGIMPWFNFGTDQSKY Rozal11 ------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------ Schco3 HAYPLIDQDPHVSRVIRYMRPSDLGVWAAATAAGPVAMMKATAFLGFVAGFMLAYQRSSLRFWGWTENKREEEKAKEGKALY--GESDQVQGSAFRNSVWTQLKFSAIPMFNFGTDPAKY Schpo1 ------------------------------------------------------------------------------------------------------------------------ Sorma TKYPLIDNDPHFRRVIGYARTSDYVHGTVAGAAGPGLLMRLATAVGFFGGFLYFYQRSILRFYGMSENAREVQMVKAGQPLY--GVSTLVQGMAARQSRYSALFFAVLPWFNFGVDTAKY Sphar ------------------------------------------------------------------------------------------------------------------------ Spipu1 VPYTFITDEPHVRDIVRYMRKDDLMLWGGIAAGFPALHMAIQIPFFATCGFLFAAQRSLFRFWGWRENDIEVARPAPAKKGW-------------------------------------- Sporo1 TPYPLVDADPHAGRVIRYFRGSDYALWAAGTAAAPAAILRLATWLGFAGGFLLAYQTTSLRLWGWKENAREIEMAQQGKPLY--GETDLIQGVAHRNSMWSQLKFGVLPWFNLGTDASKY Stehi1 TPYPLIDADPHFARVVRYMRPSDYAWWGALTAAFPGLLLRVGGVMGFLGGFLFAYQRSSFRFLGWSENKREEEKAREGKPLW--GESPQVQAAAHRNSQFSQLKFGAFPMFNFGVDPAKY Tapde11 TPFPVIDTDPHFFRVIKYTRLSDWVYAAGLSAAFPGIMMRLSWTIGAVGGFLFAYNRSASRLWGWTENAAEVERARAGKKIY--GDSELMQGVAARNSTFSGLMFGLAPWFNFGVDVAKY Thetr TPYPVVNAAPNVAETVANFSMGDVSKWALMTGLSLPFGMVMAGSIGFVGGFMWAYQNAAGRLMGTFENKSEVKR------------------------HYSQ------------------ Treme1 HKYPLIDADPHARRVVRYMRPSDYAVWAGATVAGPAALLRLTGFLGFCAGFMLAYQNSSKRFWGWSENAIEVTKLSDGKPLY--GETDLLQGVAARNSTWSQLKFQAIPWFNTGVDTSKY Trire2 TSYPLIDNDPHFKRVIRYARTSDYVAGAASAAFAPAALMRLAGFIGLAGGFLYFYQRSALRFYGATENSREVEMVKAGEPLY--GHSRLLQGVAARQSRYSALFFSTVPWFNFGVDTAKY Umbra1 TPYPVIDKDPHFFRVVRYFRPSDYAALAAGTAAAPAIMLRLAGFLGAVGGFLIAYQRSSLRFWGWEENTAEVEKIAEGKPLY--GESQLLQSVAAGNSRNAQLKFNAIPWFNFGVEAAKY Ustma22 TPYPVIDADPHFSRVVRSFRTSDYAAMAGATAAFPSAILRLSTFLGLCGGFLFAYQRSSFRFWGWRENEIEQQAVKPPGTDP--SKSDLLQGVAHRNSAFSQLKFSTLPWFNLGNNSQES Walse1 GQYPLIDIDPHFSRVVRFFRVSDYAAWAALSAGTPALYLAVPTTLGVLGGFLLAYQRSSFRFFGWTENQEEQEKAKDGKAIY--GDTQLLQGVAHRNSAFSQLKLATIPWFNFGVDTQKY Zygro1 ------------------------------------------------------------------------------------------------------------------------ [Cluster3187.fasta_al_trimmed; alignment length = 165] Allma1 LQSAMDANAQVREVIKDRVKTIDLQLRAILLQVH--TNVAQLAQLVPEHQFYRYYTSLLQTLCFVVAWQTYLEQVAERTGLIPLEDLLHGLVQLPSELARL-AVNCAAQQDYDRPLRIRAFVQELYSGFQLLNLKNDLLRRRYDGIKYDVKKIEEVVYDIKLRQL Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 LQTKIDEETAVRDELHEIVQTLSKKGRSTLSRAHS-TPSDQLKTVADKHPFYKYWTRELQNLVTSIELCAWLEEVGKFLNVLTIEEYLLALIGMVEELSRL-AVNSVTLGDYNRPVQIGKFIKDLFAGFQLLNLKNDILRKRSDGIKYSVKKVEDVVYDLSLRNL Aurde31 IENALTSDAELKEKLRDEVHELEKHLRHMLNRIHS-TPKPEIAALVPDHQYWRWWSRHQQTAVFVVSLIEYLQDAATRLGFLAAEDYLQGVISMVNELSRL-AVNSVTMGDFEEPLKISAFVKELFAAFSLLNLKNDSLRRKFDSLKYDIKKLEEIVYDISLRQL Batde5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 INAYFERDAQLREILREENAKLDKKVRSMLSKVHS-TPASDIVSLIPPNQLWRWWAYTIRSIVYIAAFTEFLQEVNDMVGIIQVEDYLQGLITLINELSRL-AVNSVTLGNYDAPFKISIFVKDLFAGFSLLNLKNDSLRRRFDSIKYDVKKIEEVVYDVSLRQL Botci1 LQTKIDEDAEVRDQLKAILQTLERQCRNALSRAHS-TPASHLASIASNHPYYKYWTRDVQNVIFAILLCGWLEEVGEILQVISIEEYLLSLISLIEELSRL-AINSVTLGDYHRPLQISQFVKDLHAGFQILNLKNDVLRRRSDGIKYNVKKIEDIVYDLSLRNL Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow IQQQFDAETSIREAIREEVRSLELSNRKLLSQVHQ--PTADIAAKVPAGQFHRYWKFSSQQSVFLASLVVYLEQIREKLGVLALEDYLFALCNLSSELARL-AVNSVTAGRFDRPFRIANFVNDLNSGFRLLNLKNDGLRKRFDALKYDVKKIEEVVYDLSIRRL Catan2 LQQVMDSESDVRDDLRTQVRVLERVLRSLLANIH--MDVAELKALVPDAQFFRFFSGPLQTACYLVALKVYLTHVAEVLGVIPMEDFLFALALLPSELSRL-AINSAAQRDFQRPARLLNFLQRLHGGFQLLNLKNDNLRRKYDSIKYDIKRVEEVVYNIKMRGL Cioin IESFLKTEHDVKEKIRDNVNDLEQDARRILQGIHQPCSAGSLSLLVGKQQYFKYWQGVTTRFSFYLSLVEFLQKVADLMGLLELDDYLCGLLLMAGELSRL-AVNCVTAGDFKTPIKISKFVYDLEAGFRLLNLKNDFLRKKYDGLKYDSKKIEQVVYDIKIRGL CocheC53 LQARIDEDSAVRDELRDIIQALEKHNRNVLSRAHS-TPVGELSQAASKMPYYKFWSRQMQGACESILFWGWLEELGEIFKILSLEEYLHSLMTLVEELTRL-ARNAVTLGDYERPLLINQFVKDLHAGFQILNLKNDSLRRRSDGLKYRVKDVEDVVYDLSLRNL Coere1 LQDKFDKESELFENVKAAIKELDRSCRLALSKAHS-LPMHKLAELITPVTFYKYWTQKLQDACALVVFAVYLADIKKHLGYFTLDEYLLGVISLFNELGRL-AVNSVIVNDVQRPQEISTFVSELYSGFQLLNLKNDVLRRRFDSIKYDIKRIEEVQYDLRVRGL Conco1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 LNELLEQDLEIREKIREQVAELDKKTRNMLSKIHS-TPSKSMADIIPPNQFWRWWTNSLRTAVYAAALVEYLDDVAKILGILPVEDYLLGLITMVNELSRL-AVNAVTLGDYDEPIRISLFVKELFAGFSMLNLKNDTLRRRFDSLKYDLKK------------- Copci LNVLLDGDSELREKIRDQVTEFDKKARTMLNRIHV-TPSDALADLIPPNQFWRWWSNSLRTAVFAAVLVEYLSQVSDQLGLLAVEDYLHGIISVVNELSRL-AVNAVTLGNFEEPLKISTFVKDVFVGFSMLNLKNDSLRRRFDSLKYDLKKIEEVVYDVSLRKL Croqu1 LQDAMDAEHEVRDRIKESVRGVEKHLRAILNQVHG-STLSQLAKLIPEGQYWRYFTRTLQHVAFITIYHNWLQDVIEILGLLTTEEYLHGLISLINELTRL-SINIVTLGMYQVPIAISQFCKDLSVGFSMLNLKNDSLRKRYDSIKYDLKRLEEVVYDITLRGL CryneH991 AIASLENDQNLRKQIKESVEPIEDLARSAINKIHS-APASQVAELIPQGEFYRYVGPIMRSLTTTIVFARFMFTVSSLIGLLSAEDYLQGVIGAVNELPRL-SINAVTSQNFELPVKIAAFVNDIFASYSLLNLRNDALRRRFDSLKYDLKRCEDVVYDLTLRGL Crypa2 LKTKIDEDTQARDELTQIIQKLERDVSYTLSRVHS-TPRSALSTAASKHPYYKYWSRTIQDAVLTVLLDSWLEEVGELFKVITIEEYLLAVTSLTDELSRL-AVNSVTLGDHELAVKISNFVKDIHAGFQLLNLKNDILRKRVDAVKYHVKKVEDVVYDLSLRNL Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi FTEELEQDFQLRQNIKEIMTKIEPIDRKLVQTYH---QVNNLKLLIKPVLYYKYWKFSITQISFSLIFSYWVDQVQSILGLLELEDYLIALCNLSNELSRY-CLNCVIKQDYETPSLISKFISDLFAGFRLLNLKNDIIRKRYDSMKYDLKRIEEVVYDISVRNL Dmel YQKYIDNEQEVRENIRIVVREIEHLSKEALQIIHS--DLSQLAELVPAGQYYRYWTFITQRLIFIIALVIYLETVAEMLGLLDVEDYLLGILQLASELSRF-ATNSVTMGDYERPLNISHFIGDLNTGFRLLNLKNDGLRKRFDALKYDVKKIEEVVYDVSIRGL Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LNSLLDRDVEIKEKLKDTVQGFEKRTRSILNKIHG-TPSDAIAELIPENEYWRWWTNTLRSAVFAVAFVEYLSGISEVLGVIQAEDYLHGLISLVNELSRW-AVNAVTLGDFERPIRISIFVKNVFAGFSMLNLKNDSLRRRFDSLKYDIKKIEEVVYDVSLRKL Fusgr1 LQEKLDEETSVRDNLTQIIQRLERAVATALSRVHS-TPRARLSEVASQHPYYKYWARTVQNAIGTAVYTAWLEQVGAVFQVFTIEEYLLSLTDLTNELARL-APNAVTHGDFELPLVISAFIKDLFAGFQLLNLKNDILRKRADAVKYDVKRVEDVVYDLSLRGL Galma1 INALLDRDVDLREKIKEQVNELDKKTRTMLNKIHS-TPPEGLAGLIPENQFWRWWSNSIRTAVFSAALVEYLAQAAGILGILPVEDYLHSLISLVNELSRL-AVNAVTLGNFEEPIKISIFVKELFAGFSMLNLKNDTLRRRFDSLKYDIKKIEEVVYDVSLRKL Ganpr1 VAERLEEESDIRERVRTAIREFDKIVRSTLSEIHSNASDDRVQELVSPELYFRYWRISLQQAVYISAMVVYLEELESYLGLITGEDFLHAVISLISDLSRL-SLNSVTAGNYTRPRAILSFITRLHAGFQMLNLKNDALRRRFDSIKYDMQRCEQVVYDLSVRGL Gloin1 IEASMEEESMRKDEIYSCVRDYEKTCRYILNRVHS-ASSEELSKIVPHQQFYKYWCRTLQKSLFIAAFAIYLEQVENLCGVITVEDFLHSFVTLTDELSRL-AVNSVTAGDYNRPLKISKFVKELYTGFQLLNLKNDSLRKRFDAIKYHIKKIEEVVYDVSLRKL Hisca1 LQDKIDEESQIRDELQDIVQTLSKR----------------LVSVAAQHPFYKYWSRELQNLVFTIQFCAWLEEVGEFLGVLSIEEYLQALISLVEELSRL-AVNSVTLGDYARPLQISKFVSDLQAGFQLLNLKNDSLRKRSDGIKYSVKKVEDVVYDLSLRNL Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LNVLLDRDVELRENIKDQVNEIDKKTRTMLNKIHS-TPWDALASIVPPNQFWRWWSNSLRTAVFAAALIEYLPKVAETLGLLPAEDYLHGIISLVNELSRL-AVNAVTLGNFDEPIRISIFVKNVFAGFSMLNLKNDTLRRRYDGLKYDIKKIEEVVYDVSLRRL Lenti61 INSILDAEIEIREKIKEQVTEFDKKTRTLLNRIHS-TRSEQLAAIIPENQFWKWWQNSLRNAVFSAVLVEYLPAVAETLGILPAEDYLHGVISMVNELSRL-AVNAVTLGDFEQPIKISLFVKDIFAGFSMLNLKNDTLRRRYDSLKYDIKKIEEVVYDVSLRRL Malgl1 -----------------------------------------LSEHVPSNEFYKWWSGCMKGSVFVVLLVFYVEAVAHVLGILTTDEYLHGMISLVNELPRL-SMYLVIKGNYNAPERIASNVNQIHSTFKELNLKNDSLRKRFDSIKYDVKRLEEILYDLTLRGL Mellp23 ------------------------------------------------------------------------------------EEYLHGLISLINELTRL-SINVISLGFFQVPIGICEFVKELSNGFSVLNLKNDSLRKRFDSIKYDLKRLEEVVYDITLRGL Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr YEEYAEKENVRKDAIREVTKELEMIQRNMLQQCHA-RKPTELADTLHGEEYYRYWRQVTQNLVFMAALWTYLEEFANLVGAVDLEDFLHGICSLPSELARL-ATNCVTMGDFVRPTRINAFVADVYNGFRLLNLKNDSLRKRFDSLKYDVKKTEGVIYDLSIRGL Morel2 IQASMENEATTKDNIRSAVRELDRTNRNILNRVHS-SSKDQLTKLVPTHQYYKYWSGPMQQACFLATLTMYLEELEGFFAVISVEEFLHGVVSLTNELSRL-AVNAVTSGDFTRPVRIGKFLKELYSGFQLLNLKNDSLRKRFDGIKYDIKKVEEIIYDLTVRKL Mucci2 LQQSLEQETNRKDEIRATVKELDRACRQLLNQVHA-DPTGPLAKLIPDNEFYKYWSRTTQQAVFLIVFKSYLPTVEETLQVIQLEDILHAYISLINELSRL-CVNSVTVGDYERPLAISKHVKDLSAGFQILNLKNDILRKRFDSIKYDVKKIEEVVYDITLRGL Mydma FNRDMTLAMEV-GNIKSITTQLNQKTTEIIQDVHCNATNQGLSTIVPHREYYRFWKNIFQKIVFACAFCEYFQKVAEIMQILDLDDYLIGVLEMASELSRL-SVNNVIAGNYEQPVKIGKFLCELDRAFRLLHLKNDAVRKRFDVLKYDLKKVEQVVYDLRIRGL Neucr2 LKDNIEKDSSIRKDLEQIIEELNQNVSYTLTKIHS-TPRSKLAQFASQYPYYKYWGRTLQDAIATVLLHAWLEEVGHVFEVITIEEYLLALISVVEDLSRL-AMNSVTLGDTELAVQISGFIKDLHGGFQMLNLKNDILRKRVDSVKYAVKKVEDVVYDLSLRNL Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 LQTKIDEETTVRDELHEIVQTLARRGRSTLSRAHS-TPADQLKAVADQHPFYKYWSRELQNLVASIELCAWLEDVGKFLDILTIEEYLLALIAMVEELARL-AVNSVTLGDYTRPMQIGNFVKELFAGFQLLNLKNDILRKRSDGIKYSVKKVEDVVYDLSLRNL Phybl2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 -----------------------MTIRSVFNEAAT-------------------------------------SAISEALKI---TDYLMALLRLAEEIVEY-TSSTIVRYGFALPVINQRLISHVQQGFQTLDLKNDSLRRKYDGLKYSVKKLNEIVYDLSLRGL Plicr1 INGLLDYDVELREKLREQITELDKKARTMLNKIHS-TPSNSLAELVPPNQFWRWWSNSLRTAVFSAALVEYLPKVSEVLGILPAEDYLHGLISLVNELSRL-AVNAVTMGDFEEPIRISLFVKGLFAGFSMLNLKNDTLRRRFDSLKYDIKKIEEVVYDVSLRKL Polpo FMNEMEEEFQLRQNIKNSTTVIDQTERKMVQMAHT-QNINNLKALIKPFNYYKYWKRHLTQIVFCLAFSYWLEVIQNHLGFVELEDYLLGLCDVTNEMSRY-CVNCVIRQDFETPLLISTFVNDLYAGFRLLNLKNDILRKRFDSMKYDIKKLEEVVYDLSVRKL Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 INRILEDDVLVREKIRDQVNELDKRARSMLNKIHS-TPWDSLAGLLPKDQFWRYWAFSIRNTVFAIVLVSYLARVSETLGLLAAEDYLHGLISLVNELSRL-AVNAVTMGNYEEPIKISIFVKDVFAGFSMLNLKNDALRRRYDSLKYDIKKIEEVVYDVSLRNL Rhior3 LQQSLEEEAQRKEEIRTAVKELDKACRQLLSQIHA-NPKGPLAKLIPPHEFYRYWSRTTQQAVYLVVFESYLPKIESSLG----------------NLSRL-AVNCVTVGDYDRPLLISKHVKDLSSGFQLLNLKNDAIRKRFDSIKYDVKKIEEVVYDITLRGL Rhoto1 LQDALAKDAELRERVREATREIEQAERACLGRVHS-HSREDLADLIPPQQFYRYFSRCIQQASYIVVFRVFLEEVAQQLGILSTEEYLHSLISLVNELSRL-AINRVTLGDYAAPVQYSRFAKELSNAFGLLNLKNDSLRKRFDSIKYDVKRLEEVVYDLSLRGL Rozal11 VLPILEEQEVKKENIRAASKQLAVCARNFVNSFHTEESFEQVSSIQPVELYFRYFNHVLQDILSSLHIFHFIETIRTYLGIITLEDFLQSIPPMISEIVRL-AINRVPSKDYHFVTSTCTFVKEMYSNLQILNLRNDSLRRKVDGVKYELKRIEEVVFHLSMRNL Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro FQDVADAEQEKREAIKDVVKTIEPKMREILQQCHH-LPADKLAEKVPPGEYYRYWRWVTQQTVYLAALMTFLQDIQNLLGVIDVEDYLMGLCSLPSELTRL-ATNCVTMGDFERPVTISRFISNLYDAFKLLNLKNDSLRRKFDSLKYDVKNVEQVVYDLSIRGL Schco3 INALLDQDVELREKIKEQVTELDKKTRTMLNKIHS-TPSAEIAAIIPPNQFWRWWANSLRNVVFSAALIDYLQRVEEILEVLPPEDYLHGIISMVNELSRL-AVNSVTLGNFEEPIRISVFVKDLFAGFSMLNLKNDTLRRRFDSLKYDLKKIEEVVYDVSLRNL Schpo1 LQDQIDKEHSIREKLTAEVDLLDEKLRVLLANCEQ-NLENQLAELASNFPYYKYWDRSIQKVVYLYLLASWTSEVGQILQVLSIEQYLHAVLSLCSELARQ-SVNSVISGNYHIPFEALNTIQKVHSSFQVLSLKNDSLRRHFDGLKYDLKRSEDVVYDLRIHKL Sorma LKENIEKDGSIRKDLEKIIEELNQHVSYTLTKIHS-TPRSKLSQFSSQYPYYKYWGRTLQDAIATVLLCAWLEEVGEVFGVITIEEYLLALISVIEDLSRL-AMNSVTLGDTELAVQISGFIKDLHGGFQMLNLKNDILRKRTDSVKYAVKKVEDVVYDLSLRNL Sphar -----------------------------------------LQQRVPLDQFYRYWKWSAIQLVFSAALIQFTGEIDRLLCCIDIEEYLLGLCQLSQFLARL-AVNSVIAGRLQRPAEVLAFLSELLGALMGFSFRNDQLRKRFDGMKYDVMKVEEVVYDLSVRGF Spipu1 IQRSLETETELRENIRTAVRDLERTCRTVLSQVHSATTDSDVAKLVPHEQYYRYFTFTLQQAIFLAAYIVYLPQVEEMLGVIGIEDYLHGLVSITSELSRL-AVNCVTHGDYSRPLRISKFVGDLYSGFQLLNLKNDALRKRFDSIKYDVKKIEEVVYDISVRGL Sporo1 LQDSLTLDQSIRERLKDQSKVIEQAQRPILSRVHS-TRASELASIVPKEQFYRYFARSIQQSSYIVVLRTFLDQVGKELAILSTEDYLHSLISLVNELSRL-AINRVTMGDYSAPVQYSRFAKELSNAFGLLNLKNDSLRKRFDSIKYDVKRLEEVVYDLSLRGL Stehi1 INNLLDHDADLREKIKDHVTDFDKKSRTMLNKIHS-TRSSDLADLVPADQFWRWWSMSLRQSVFSAILIEYLAVTSDQLGILSVEDYLHGVITMVNELSRF-AVNAVTLGDFEAPIKISIFVKDLFAGFSMLNLKNDTLRRRYDSLKYDIKKIEEVVYDVSLRKL Tapde11 LQESIDRDAAFKDEIREVTNELDRIHRQILAQAHS-VPSDKLAKLASQMPYYKFFTNQLQNASYTAVFAHWLEEVGTVLTL---------------------EVNSIYTP--SSP-------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 AITSLEAEQSLKKTIREAVDPLDDVARSALNLLHS-IPSSEVASLIPKGEFYRYIGPTLRSFVTAVAMAHFLFAISSLLGLLSAEDYLQGVIGMVNELPRL-SINAVTTQNFFLPIKISAFVNDIFASYSLLNLRNDALRRRFDSLKYDVKRCEDVVYDLTLRGL Trire2 LEAKLEEETQIRDAISQLVQRLDRSVATALSRVHS-TPRARLDKVASQHPYYKYWSRSVQHAIGTAIYCAWLEEVGAIFSVLTIEEYLLSLADLTSDLARL-ATNAVTLGDFQLPLTISAFVKDLFAGFQLLNLKNDIIRKRADGVKYDIKRVEDVVYDLSLRGL Umbra1 IQQRLDEETARKDEIRQIVRDLDRTARIQLNRIHA-DPTGPLDKLVPETQYYKYWRGTLQQILFLVAFSTYLAEFQDALELIPYEDVLQSFISVANELSRL-AVNSVTSGDYDRPRRISSFVKDLMAGFQLLNLKNDNLRKRFDSLKYDLKRIEEVVYDVSLRGL Ustma22 LFEELEAERRLADVLRDKAHELDRLSRQLLADLYS-SEARELACVLPEDGLYRWYSFAFKNLTSTIAQLVLLQQASHVLGLLVTDVYLHALINAINQLPRL-ALNSVTLGDYSTPLRLAEFVKQVHSGFQLLNLKNDSLRKRFDSLKYDVKNIEEIVYDISLRGL Walse1 LNVTIEKDNDYKQSLRDTVSLMDEHLQNAAQRIHT-TKQEDFANKMSDIEYLKYWSRSIQTYMFIQLLLNYLKEFNEFTKY---YDYLFALISLVNELTRL-TVNTVIMNEFDRPKRISAFLKDVYQGLSLLNFKNDALRRKFDSLKYDLNKVEGVIYDLTLRNL Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3189.fasta_al_trimmed; alignment length = 294] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 EIDHFASNLIEQEIKSNINKSYNELMQVNKELAVASTELKDLRSKVQQRSSVIILELSSLFRSVEGAQKYIAPAPGRRILLEHATRIFLLNDMILVAELVANQCCSLRELTVLSFHFGNKHS-LYRSRTPT--GYTALLNEIKSAKLVYEELEELSVPVTRMNFGLAILHSIENILITQKLTKSLIL-LGAEALQLFLHNRSNFIQDLVLQVGVHDNSNSYITQVAVIRCQTIKKVAIQFQKLFEGYSSVLVSWCNDEVDKHFFLMKKQLINDDQLTPQAIKISRKQI-DE-LK Aspfu1 EIEEYQNNLTSTDLQQNVYQNRTQFIKISKEAEKLKGEMRTLRTLMAERSSVANLELQTLWKTVEGSQKFLPVAPGRHIVMERPVHIVLLNDHLLVAKLVAEECWPLQDVDMIANAINVRKTFTYRHDKRDSSDKGELLATFRKAVWVDGQVDELDIDIALQRFEEAVIERLRKLALASVLVTWLTR-LGDQAREAYLKARSDVISKRVRACVFEGDLPLYIFQVSYVYFTLIKNTINIYQQCFPALTSACIKWAKHHLDGFNALLTRQLSSGTTVWQKCIDIVHEHA-DS-LT Aurde31 ELRSLQSTLTAADLQRNVFKNYAEFMVISKEISTLENDMLDLKECLSERSSVADLKIQTLHGYIEGSAKFVPITPGRHIKIEYPVHMVLLNDALLVAKLVAEKCWSLSEIVVLTNLIKIREVFVYRVGKTS--QKKVLLLQFRQVAWIDSFGDKLTVAIALREWDEAVVEEGEKKLLVSALASLLAR-LKPAAVTTFLAARGDLSRKRVRSIAMEGDIVNYVSDLCVVVFCSVKHTADWFLAAWKEVASYFVQWAREQIEAFAVLFRKQVYGTRKVMIEALTLVRQQNKKF-LQ Batde5 AIQQLYHSLAATDLQCNVYRNYNDFVVISKEISKLESDMLYLRELLTDMAEALAKQMKLLYTNIDGLQKILPESKQRYLVRDDMVHLYLFNDTLVQVRMFAEIAWGLSEIGFVSNAFKIVDASIYRTETLE--EKRAILASIKRITWLLELPDELDVLVAHRDFDNSVINTTRKILLAKLVIDRLLR-LGDQARDIFLTARTKTIRHRTRHLKFDGDVAAYMCDLAEVTFRLIRNTCDWYGGSFRDMASGFMKWVTLEIVYFTDILRRQVFNSFSVIADCLSSALDQC-QQ-LR Botbo1 ELKSLQSSLAATDLQRNVFKNYAEFVVISKEISTLENDMLELKESLSERNSIADLRLQTLHTTVEGSAKFVPSIPGRHIVMEYAVHFVLLDDLLLVAKLVAEKCWTLSEVTIITHAIKIRETHVYRADRSS--DKKNILSTFRTSAWITDFTDELSVAIALQEWDEAVIERGEAKLLTSALTSLLLR-LHPVARDTFLATRTEFIRKLTRTIRFEGDIGVYIGEFAMVMFTGIKHTADWYLASFREMASGLVQWAKEQLEIFAKMFRRQVYSDQRAVQNSLQMTRTQSKRL-LQ Botci1 DIEDYQTNLTSTDLQQNVYQNRTQFIKISKEAEKLKGEMRALRNLMAERSSVADRTLQALWKTIEGSQKFLPAAPGRHV-------------------LVADRCWPLLDIEILADAIMIRESFTYRTEKPGDTEKSSLMMNFRKAVWVESQVDELDIEIALQHFDMAVVAKLNTLALAELIISWLTS-LGDRAREAYLEARGGIIHKRSRQCIFEGNLHQYIWEVSFVYFTIIRNTVSTFQACFPQLMSACVKWAKEQVDAFNVILARQLSSNGQVWTECMDQAREHA-KM-LS Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl DIDLFTSNLVQEEVKRNIYKSYNEIITVNNDLHEASAELKQLRSSISERTSVMILELATLYKNVEGAQKHLGPASNRHLLIEQTVQLYILNDAVLVAELIVSQCCPIRDVTILMFNFGNSTC-LYETRDIN--ECMRVLDAFRKAKLVDNLIEEVDIDLARLKFDSAVLLEAESQLILTKVVKTLIR-LGEAGLDLLLQNKSNLIQELLLQVGSSEHPSLYLTELAIVRFQIIKRTVIVFRELFHRLSSILVSWCSHEVEKHFNLVSKQLLNGDKLSPDAIRYSRKQI-DD-LK Capow WLRDNVESLVSRTLKKNVFRNYTRFIDTTKEIAKLEGDMYQLRYLINETITVGDDDLRATWREVEGSEAAMGQLPNRDRMLVQTIKLFLFNDSLLTAPFKVHRFCSLKEVAFAQNVFKVIDALLCQSA-----QKRQWLDTVDRVQWIVDMPDNLDVFIAHRNFEAAAIEKVSQYLLTSTLVALLLR-LGEKARTMFLSNRSFGMQREQRRLRIEGSALFYITKLSKVFFARLAEVASEFRQLFADSKSAFSVWVVTETEQFCETFSRHVFHQFSIVVQCVEIAVTEC-QS-LK Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 DINRYQDELTSLDLQHNVYQNRTQFIKISKEAEKLKGEMRTLRQLMSDRSSIGDLNLQQLYRDVEGSQKYLPPIPGRYIVWKRRVRLLLLNDHLLIAEFTAQRCFPLLDTHV-EERIIIRETFTYDTKKEDSGDKSAFVATFRKTKWVESQLDDLDIEIALQHFEEAVVDRLKSLALANVLVSWVVQ-LGDRAREDYLEARGNLIKTRSRQCVFEGNLPDYIFQISYIYFTIIKNTVDMFQRCFPQLMSACVKWAKEHIDQFNVLLKRQLSSGGNVWNECLRLAHEHA-EM-LR Coere1 NIRQFRKSLASKNLQKNVYRNYESFVFISKEISSMERDMQLLRELLHGRMSMANQQLAKIWRTIRDAQRLVPFAPNRHVVGDQKVDIVVFSDMILLAVLVADRSFELSNVTVSGFLIKLVETFLFGFRSAE--AKNELL-------RMDEQLDALDICIARREFSQATVQQLKEQLLARLIVALLHR-LGKEAKGAFLASRTATIKNRTRQLKLEGNTRLYIRELAIVYFRLIRNTCEWYSALFADMISALIAWVRQEMAGYAAIFRRHVFHRFQVIASCLNHTLAEV-DI-L- Conco1 GIKSFHQNLSTQKIQKHVYRHYHEFVTISKEITKLETDIIELHDILADLGSKTDLNLSKIWKAVQGSEDYLPHIPFRCPIMERDAHFFLLTDSFLVASLIARSCWSLKEIHVVENAFKISETFIYMAMNKE--EKRRFLKALARANLDSDFWNNLDVSINHHKYKEATILQATSIILCNILVKLLIK-LGEQAQKVFFESRKNIIRIRIRQLKLDGNTLNFVRELSRTVFLLILNTCKWYTPNFTNMGSALINWVRSELENFCQLFRNQVFDEFSVIELCLREANKECRK--LR Conpu1 ELKSLQSSLTAVDLQRDVFKNYAEFVFISKEISVLENELLELKESLTERSSIADLRMQTLHTQIEGAATLAPTTPGRHVVHDHTVKFVVLDDAVLIAKLVAERCWPLIEMLVLTNVFKVRETYVFRTEAAS--DKRSLLAQFRTVAWVGDFTDELTVAIALRQWENAVVEKGTAKQLEGALVGHLVR-LGPAARRALLAARGEAIRGYVRAIRFEGHVGMYVHDLSLVVFSAIKHTADWYLGAFSEMSSGFIDWAKTQLEAYADMFRKQVFGDQPTIDEALAIAHAQHRKV-LQ Copci ELRSLQSSLTASDLQRSVFKNYAEFVLISKEISVLENEMLELKELLSDRSSVADLRMHALHTSIEGAAKFVPTTPGRHVVGEHKVKFVVLDDAVLVAKLVAEKCWALNEMIVMTNVFKVRETHVYRTETAQ--EKKSILTLFRQVAWVGDWSDNLTVAIALKEWNKAVVEEGQARALTQSLISLLNR-LKSAARTTFLEMRGKVIHSLMRKIPFEGHVGTYIGELAVVFFTGIKHTADWYLASFKEVASSFITWAKQQIEKYGEIFRKQVYSEPQIVEESVQITLNQSRKL-LE Croqu1 HLKSFKDKLTNEELQVNVYKNYSAFVAISKEIATLENEMLELKTVLEERNSIADVNLEALWENVEGSQKFLPILPGRHLLAEQNVHLFLLNDALLVAKVMADRCFNLGEISVLDNAIKITETAIFRTDRLE--DKRALLSSFKKVAWIGDLSDELSVSIACRAYDEASIEKSKEILLMNKLSNLITK-LSEKAKQSFLSMRSELVKTRSRMIKFEGDIVLWVSQLAMVIFTLVKNTCEWYMTAFKDMASGFVRWAAEQIELYAEIFRRQVYGDAVLIQDSLAVTKAHS-SM-LK CryneH991 EKRRFVAALNKKELQRTVFKSYAEFVAISKEISTLENDMLELKELLGQRNSVFDLQLTQLWSIVEGSQKYLPVVPGRHLVFEQNVNIFLLNDVLLIARMVAERCWNLVELGILVNVIKVHEHCVYRTQKSD--DKRALINAFRQIS------------------------------LVSQIISLLVR-LDDHARDSFLESRKELMFKRVRSIKCDGDVSIYINELAVVIFTIIRHTSDWYMNAFKEMASGFVTWAKQQIETFAELFKRQVDASESIVNECLHVTATQNRKL-LR Crypa2 ELREFEDQLAAADLQQNVYQNRTQFIKISKEAETLKAQMRGLKNLMSERSSVADRTLQALYKNIEGSQKFLPNTPGRHIIQNRSIAIVLLNDHLLIAKLVADRCWHLLDIEVLADAIMVRESVIYRTEKPDDPDKRTLLLNVRKVVWVESQMDDLDIDIALQRIEPAVVEKLKGLALAALVVSWLTR-LGDRAREAYLEARSQIIQKRSRQCIFQGDLHSYIWQLSFVYFTIIKNTVSCFQGCFPPMMSACVRWAKEEVEAFNVILARQLSSGTEAWTKCMERAQEHA-QM-LS Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 KIDDFTSQLSKNDAKSTISESLESVLNVSDSVADTYKVLDNLKQTINARRSVLILEMGQLFKEVDGAQQFVSAAPGRHVVTQRPAHLIISNDYLSVARTIATGCWPLRSVTLFTLAFKTSTSLLFQTDSQN--EYNKVKSSFGAAKSIDESLTNIEVFLGHHKFEECTVNRLKDQLLSWKVTINLFRILGDKGRNVLLDAKTKQLDERVREVKFEGDLKNFLMQVSMIYFNFIQQVYVLYEKCFTE--SFVIDWTNDRIASYNKVVQRQLIDDSKIYKDCVLMTKSRA-QP-LR Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 ELKALQSSLTNVDLQRNVFKNYVEFMTISKEISTLENDMLELKASLSERSSVTDLRMQTLHSQIEGSSKFVPATPGRHIVTQHLVKFVLLDDAVLVANLVAERCWPLNDILVMTNVFKIRETFVYRCDLSG--DKKILLAQFRQVAWVGELTDKLTVAIALREWDKSVVEEGEAKKLTTSLTSLLNR-LHAAARNAFLASRAALTRQRIRMIRFEGHVQMYINDLATVVFTGIKHTADWFLASFKEATSCFVEWAKTQIGLYADMFRKQVFSDDETVRKCISTTHTQNKKL-LH Fusgr1 QIREFEESLVGTDLQQSVMQNRTQFIKISKEAEKLKSEMRNLKNFMSERTSIADRSMQALYKGVEGSQKFLPNAVGRHVVQDRAMQIFLLNDHLLIAKLVADRCWPLLDVEVLADAIMVRESFIYRTEKPQDPEKKQLLLNVRKAIWVESEMDDLDIDVAMQRFEDAVVEKLKAIALANMIVSWLTR-LGDSARESYLAARSGTIHKRTRQCIFQGDLHLYIWELSFVYFMVIHNTVQCFQSCFPPMMSVCVKWAKEEVDAFNIILARQLSSRGQVWTQCMERAKEHS-KL-LS Galma1 ELKSLQSSLTSSELQRSVFKNYAEFVLISKEISVLENEMLELKDLLSDRSSVADLRMQTLHASIEGASKFVPTTPGRHVVGEGKVKFVVLDDAVLVAKLVAEKCWPLNEMLVMTNVFKIRETHVYRTETPS--DKKSLLSQFRQVAWIGEWSDDLTVAIALKEWGKAVVEQGQAKVLITSLISLLNR-LKAAARNTFLEMRSQVIRGLMRKIRFEGHIGTYIGELAIVYFTGIKHTADWYLASFKEVASSFISWTKHQLEDYCEIFRKQVYSDPQVVEEAINITLSQSKKL-LQ Ganpr1 TVRTVHSTLAAADLQRSIYRNYTEFIAISKEVSKLESDVLILRGLLGDMAEGLDRSAERVYDVVDGLSKLLPSSPNRRLLRDQSCQMFLFSDALVIARMQAERCWMLSEIAVITNGLKIMDVFIYRCDAPE--IKKQWLAALKKAAWLTELPDELDVFIALREFDEAVTDKAKLIILAGVIIDRLLR-LGEQAREIFLTARSSLIKHRVRQLQFDGDITQYIAELAVVVFTIIRNTCDWYTSSFKEMASGFLKWVKTEIEQYAAIFRRQIFDNFAVIADCLQATVEQS-RT-LR Gloin1 GVRSFLGTLAASDLQRNVYKNYNEFVVISQEISKLESDMLVLRGQLNELNNATDMQIQELWAGVEGAQNFVSLEPGRHILREQSVHIFLLNDCLLVAKLVADRCFSLEDITLQVNFIKILDQFIFQAGNAD--EKKNLLNMTKRATEMEDLADELDVHIATREFEQAVIEKAKNALLSLAITRWLLR-LGEQARELFLVARTENIRIRTKQLKFEGDIPQYINELSLVYFTLVKNTCDWYNSAFRDMASGLVKWVQEEMEHYASMFKRQVYSEDSTIQECLRYAREHC-LM-LR Hisca1 DIREYQNQLTSTDLQQSVYRNRTQFIKISKEAEKLKGEMNTLQGLMSERSSVANLELQALWKTVERSQKFLPAIPGRHIILERPVHLVLLNDHLLVAKLVAEECWPLQDIDVVPNAVNIRKSFTYRSDKREGSAKSDLLMSFRKALWVEGQLDELDIDTALQRFDNAVVEQLRKLALAETIISWLSR-LGDRAREAFLHTRTEVITKRARQCVFEGDLRLYIFQISYVYFTLIKNTIGIYQHCFQAMTSACIKWAKEQLDSFNAILVRQLSSESSVWQGCMETVHEHA-AL-LL Klula1 DIDQFTSNLIQDEIKFNIDKSFKEILIVNKGLETATTELKVLRTKVQERTSVYILELMTLFKNVDGAHKYITSTPGRHILLEQKVRLFILNDVVLIAELTVSRFSPLRDVTVLSFNFSNKHT-LYRHRDPQ--VFSKVIDIIRQAKRLDDALEDLDLEIGRQNFDLAILNHIQSSLLYTKLMLNLVA-LNVDALEVFLQNRSNFINDLTLQIGIIDNVTSFITQVAIIRFQTLKKVTQQYLEVSKNYTSLLVCWCSEEVDKHFQLMERELSNSSTLSVQAIKITRKQI-DE-LK Lacbi2 ELKLLQSSLTASELQRSVFKNYAEFVLISKEISVLENEMLELKELLSDRSSVADLRMQAIHASIEGAAKFVPTTPGRHVVGENKVKFVVLNDAVLVAKLVAERCWALNEMLVMTNVFKIRETHVYRTDTPQ--EKKSLLSQFRQVAFVGDWSDDLTVAIALKEWPKAVVEQGQAKLLTTSLISLLNR-LKAPARSTFLEMRSKVIRGHVRKIRFEGHIGSYIGDLATVYFTGIKHTADWYLASFKEVASSFITWAKEGIQSYAETFRKQVYSDPKVVEDAIQITHTQSKKL-LQ Lenti61 ELRLLQSSLVAVDLQRNVFKNYAEFMLVSKEVSTLENEMLEFKEALAERSSIADLRMQNLHMQVEGSSKFVPTTPGRHIVTEHSVRFVLLDDAVLVAKLVAEKCWPLNEMLVMTNVFKIRETHVYRTDISA--DKKNLLSQFRHVAWIGDWSDELTVAIALREWDKAVVEEGEGKLLTAALIGLLVK-LKAAARSTFLAARADVIKKCVRKISFEGHIGSYIGDLATVVFTGIKHTADWFLASFREVASSFVEWAKTQIELYAEMFRKQVFSDSRTIDEAIQITHVQSKKL-LE Malgl1 GLQTLQTTLTQKQLKEQVFKNYSEFITISREIATFENDMLEFKELLSERNSMVDLELTSLWENIEGSQKFVPFIPGRHLVAEQAVALFLLDDLLLIAHLVAERCFNLSEIVVVRNAIKIKESFVYRTERAQ--DKRALLRAFRGVGWLNSVIDDLAVHIALREWEAAVVEEGKKRLLVNAIAALLVR-LDREARDLLLEARSDLLHRRTRQIKYEGDVSLYISELAMLYFTLIKNTGDWYMAAFKDMASGFVQWASDQVKSYAETFRRQVYGDPRVVQEAIDITRKCA-QL-LN Mellp23 HLKDFKDRLTNQDLQENVYKNYSAFVAISKEIATLENEMLELKTVLEERNSVADVNLEALWENVEGSQKFLPVVPGRHLVSEHNVHLFLLNDTLLVAKLVADKCFNLGEISVLDNAVKITETALFKTDRSE--DKRALLSSFKKGAWIGDLSDELSVSIACRAYDEASIEKSKTILLMQKLSNLITR-LSEKAKRSFLSMRSELVKTRSRMIKFEGDIALWVSQLAMVIFTLIKNTCEWYMTAFRDMASGFVRWAAEQIELYASIFRRQVYGDVQSIQDCMSVTKAHA-SM-LK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr KVAEFKAQINGMQLRENVFRHHGTYISTAKEISALEAQLHQVEHLL--ENKVRDLELEWTIHDVDGLDRLQTELENDSLLHQAPVMLFLYHHLFVLAPLQLLEATPTSQFAVLVNAILLEDRYILVAEAPA--QKNTWLRFLRRVAWLVDAPDDLDVFIAQRRFQEAVVDSAHAALLAQVLVFLMLR-LNDDARRKYLRYWSNEITRQMRNLKVEGSTNLFIEKLSSTFFSILSATCQEFPELFGNAMSIHAHWLKHEVVAFAAVFIRQVMDTLTDIAAATDVVLQHL-DR-LR Morel2 TVRAFLQSLAAEDLQENVFKNYNEFVTISKEISKLESDMQTLRGLLDDVSSMSDLTMMALWEGIEGAQKMLPYHPKRHLIREHPVHIVLMNDTILIAKLLGDRCWSLTEITVVRNAIKITDVFVYKTEKGQ--EKQTMLVNIKRTTWLAEFTDELDVMIAQREFDAAVIEKATVILLSRAIVGWLER-LGDQAKDVFLTNRTKVVRQRMDQVKPKKDPVLHVEELAMIVFTTIKNTSEWFEESFKDMSSALVKWAKQEMECFADLYKDIVFSNFQVIADCYKVTQEQCNK--LK Mucci2 ------------DLQRNVYRNYTEFVSISKEISNLDADVLSVKEYLNEDLMANDQTIMALWDNVEGSQRFIPHAQNKHIVREQAVHLFLLSDCLLLARLVADHCWNIQDLTILTNALRIVETFIYRSERPE--DKLGLLNAYRRLIWLVDLPDHLEVSIALREFEKSVLEKARHIVLSQIIVNWLLR-LDEKARQVFLGTRTLIIKKRIRQLVFEGDITTYISELALVVFTLIRNTCEWYRDSFKQMASGFVTWVREQTEVYADIYKRQVFGSCQVIADCFKSTLEQC-SV-VM Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 EIRDYEDALAAADLQQNVYQNRTQFIKISKEAEKLKGEMRTLRNLMLERSSITDRTMQALYKSVEGSQKFLPNSQGRHVVQNRSMQIFLLNDHLLIAKLVADRCWHLLDVEVLADAIMVRESFIYRTEKPEDPEKTTLILNIRKTVWVESQMDELDINIALQQIEPAVIEMLKNLALATLVVTWLVR-LGDRAREAYLEARSEVIQKRSRQCIFQGDLHLYIWEISFVYFMVIRNTVICFQSCFPPMMSACVKWAKEEVDAFNVILARQLSSGGEVWTECVNRAKEHA-SM-LS Orpsp11 -------------LTDDIYK----------------------------KYSILDIN-------------------------------LIFEDIF---KLI--------------------DSCVFTTGGVQ-----------------------LDIHFFLQVCEKFI--------LCE-----------YALRSYYLTLTTE-----------------------------------------KE----------------------------------------------NP Pench1 DIRKYQESLTSTDLQQNVYQNRTQFIKISKEAEKLKDEMRTLRTLMAERSSVANLELQTLWKTVEGSQKWLPAAPGRHIVLERPVHIVLLNDYLLVARLVAEDCWLLNDIDMIGRSISIRKPFTYRHD--DASAKQELLATFRKAVWVEGQVDELDIDIALQRFEASVIERLRKLALAGILVTWLTR-LGDQARETYLKARSDVIGQRIRACIFEGDLPLYIFQISYVYFTLIKNTIGIYQQCFPSMSSSCIRWAKHHLDGFNALLSRQLSSGTSVWQKCLDIVHDHV-AL-LV Phybl2 GIRAFHKSLVGGDLQRNVYRNYTEFVAISKEISNLDGDVLHLKGYLNEELMTTDMQIVALWENVDGSQKFIPYAQDRQIVREQAVHIFLLNNCILVAKLMAEYYWNLEDTTMLQNSLKIVNTYLFRADRPE--DKLGLLHAYRRVMWLTELPDELEVLIAIREFENAVIEKARTIFLCTTIVGWLLR-LDEQAREVFLATRSLIIKKRIRQLIFEGDIPTYIGELALVVFTLIRNTCEWYRDSFKQMASGFVNWVREQTNIYATIYKRQVFNSCQIISDCFKSTLDQC-AI-VR Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 ELKTLQSSLTAVDLQRNVFKNYAEFVLISKEISTLENEMLELKDSLTERSSVADLRMQTLHAQIEGSAKFAPTTAGRHVVTEHSVRFVVLDDAVLVAKLVAERCWPLSEMLVMTNVFKIRETHVYRAEHAA--DKKALLSQFRSVAWVGEFADELTVAIALRQWDEAVVEQGKAKLLTTSLISLLLR-LNAAARSTFLNARTESMRRHIRAIRFEGHIGMYINDLAVVVFTGIKHTADWFLASFKEVASCFIDWAKQQIEHYAEMFRKQVYSDPKVVEDARRITLNQSKKL-LQ Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 TLKAFKDSLTNQSLQENAYKNYGAFVAISKEIATLENEMLELKAVLEERNSIADVNLESLWENVEGSQKFLPIQPGRHILSEQAVHLFLLDDSLLIAKLMAEKCFNLAQISILSNALQIQEKVILRTDRAQ--EKRELLDSFRRVSRIGDLLDEVSVGIACRRYEEAIVERARSMVLADRLITLLGR-LAERAKETFLTMRSELVRRQIGQIKFEGDLALWVSQTSFVLFTLVKNTCEWYMTAFKDLASGFVKWAVDQLDLFGEIFRRQVYEDQWTIQESISVTRAHA-GM-LK Punst1 ELKSLQSSLTNADLQRNVFKNYAEFVHISKEISTLENEMLELKDSLSERSSVADLRMQSLHAQIEGSTKFVPTIPGRHVVSEHAVRFVLLDDAVLVAKWVAERCWPLNEMLVMTNVFKIRETHVYRTEVAA--DKKALLAQFRHIAWLSDYSDGLTVAIALRDWDKAAVEEGETKLLTSALIALLVR-LHPAARSTFLNARAEVMRKRVRSIRFEGSVEMYVNELAVVVFTGLKHTADWFLASFKEVASGFVEWAKHQMEAFAELFRRQVYTPPQIVSEARRIAFVQSKKL-LE Rhior3 GIRGFYRSLVGGDLQRNVYRNYTEFVFISKEISNLDADVLSIKEHLNEDLLGTDMMIMSLWENVEGAQRFIPQAQHKQIIREQAVHLFLMNDCLLVARLVAEYCWSVEDLTIV-------------SERIE--DKLGLLNAYKRMMYLVELPDQLEVLIALREFEKSVLEKARHIVLCSIIVNWLLR-LDEKAREVFLATRSLIIKKRIRQLVFEGDISTYIGELALVVFTLIRNTSEWYRDSFKQMASGFVTWVKEQTEIYAEIYKRQVFGSCQVIADCFKSTLDQC-SI-LR Rhoto1 DLRRLKGRLAETELQKSVFNNYADFVLISKEIATLENEMIELKGVLEERNSIADLALSALWENVEGSQKFLPYTPGRHIITEQPVHLVLLNDAMLVSRLVAERCFNLSEIVVLQNAVKIKETIIFRTDKPE--EKKMLLLAFKKVAWIGDFSDELAVDISTREFEDAVIEKGKSILLVSALTSWLLR-LGERARETFLSARGALVRKRARQIKFEGDISMYISELAMVCFTLIKNTCEWYMAAFKDMASGFVRWASEQVEIYAETFRRQVYGNGKVIEESLEVTKAHG-AM-LR Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 TIDKFTSNLVQEEVKLNINKSYNEIMTVNNDLNVAMLELKRVRANINDRSSVLILELDQLFKNVEGAQKFINSTKGRHILMNQMVQIFILNDLVLIADFIVSQCYPLKDVTVLLFKFSNSSS-LYECRDAD--ECSRLLDVIRKAKFLDEGVEEIDIELARLRFESAVLLDIESQLISSKLTENMIK-LGEQALDLFLQNRSNFIQDLILQIGSVDNPTNYLTQLAVIRFQTIKKTVEDFQDIFKEISSILVDWCSDEVDNHFKLIDKQLLNDEMLSPGSIKSSRKQI-DG-LK Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 EIKSLQSSLMAVELQRNVFNNYAEFVQISKEISTLENEMLELKESLSERSSVADLRMQALHAQIEGSAKFAPTTPGRHVVNEGKVKFVILDDLVLVAKLVAEKCWPLNEMMVMTNVFKIRETNVYRTDTPA--DKKALLSQFRQVAWVGEWADELTVAIALREWEKAVVEQGKAKSLTSALISWLLR-LEPAARSTFLNMRTQVLRSLVRKIPFEGHVGAYVGDLAVVTFTAIKHTADWFLASFKDAASAFIEWARHQIEGYAEAFRKQVYSERKVVDECMTITYSQSRKL-LQ Schpo1 EFVSLYNKLVRKNLEKNFYKNLNEYVFISGEVESMTSDFKKFQSLLKT--------VQRLRSSIEGLDEAFWEAPQRQLICELLVNMLLFNDRLLVTQVLYN--WNLTEISIPAGAEMLQEVSLYKLSINHN-NKTTLLAVHNSEEEISMQFDHLDIQISLQEFTDAILALIQNKLVTEILVRYLRS-LGKEGQGVFMKSRTLLIKEKCLNVQLEKDTPNFIDACAFIVFRCLAQTTSSYLQLFELLDPAYRNWIFQQIEALVDLIENQYKHHDRSYTDAVSKIMTYN-TE-LK Sorma EIRDYEDALAAADLQQNVYQNRTQFIKISKEAEKLKGEMRTLRNLMSERSSITDRTMQALYKSVEGSQKFLPNSQGRHVVQNRSMQIFLLNDHLLIAKLVADRCWHLLDVEVLADAIMVRESFIYRTEKPEDPEKTTLILNIRKTVWVESQMDELDINIALQQIEPAVIEMLQNLAIATLIVTWLAR-LGDRAREAYLEARSEVIQKRSRQCIFQGDLHLYIWEISFVYFTVIRNTVICFQNCFPPMMSACVKWAKEEVDAFNVILARQLSSGGEVWTECMNRAKEHA-TM-LS Sphar ELRAYQQSTAAQDLKSHVFQNYNLFIETSREIAKLDNDLQDIRALLSEASAQQQMKLMDIAARIDGCPADFLKYPNRHLLMERTVRFFVFTDIVLVSRLM--YIWDLERLLLVQNAFRLMHAGVYQCGDHQ--SKQDFLYTIHTQQWVFEASDDLDVYIAQREFEKAVIHKTQAFVITGLLIKLCVS-LGNRARAMFLKNRGGGLHRDMRHIKIEGVTEVYVYKLSQMFFNFIRTVTMEFLSSFSASGAALVVWAASQVVHYVTIFKRQVFMSFSTAVKCLIITQENS-AP-VE Spipu1 GVRGFHQSLAAVDLQRNVYKNYNEFVLISKEISKLESDMLTLRSLLSDALSGLAKQMEALYETVEGLQKVLPEWRNRYLVRDQNVHFYLLSDTLLVTRMVLDKCWSLADVAVVSNAFKVMDMFIYRSESLE--EKRSFLGAFKRFTWLMELPDELDVLIAHRDFDHAVIEQARHTLLAQLVIDKLLR-LGDQARDFFLTARTAIIRHRIRLIRFDGDVAVYISDLAEIVFRLIRSTCDWYGGSFRDMASGFMKWVNQELQNFGTIFRRQVFDNFSVIADCLQHTLHHC-KQ-LR Sporo1 DLRRFKNQVTESELQRSVFNNYADFVVISKEIATLENEMLELKGVLEERNSIADLALSALWEGVEGAQKFLPYVPGRHIITEQPVHLFLLNDAMLVSRLVAERCFNLSEIVVLQNAVKIKETIIFRTEKPE--DKKTLLLAFKKVAWIGDYSDELSVAIATRSFEDAVVEKGKTILLVSSLTGWLLR-LGEHARETFLTARGELLRKRARQIKFEGDISMYISELAMVCFTLIKNTCEWYMAAFKDMASGFVRWASAQVEIYAEIFRRQVYGDGKVIEESLEVTKAQG-AM-LR Stehi1 ELKSMQSSLVAQDLQRNVFKNYAEFVLISKEISNLENEMLELKESLAERSSVADLRMQSLHTQIEGSTKFVPTTPGRHVICEGGVRFVVLDDAVLVARLVAERCWALNEMLVMTNVFKIKEVSVYRTESSA--DKKSLLSQLRHVAWVSDFCDDLTVSIALRSYDSAVVEQGQAKLLTTALIGLLVR-LGAEARVAFLRARREVVRRLVRMLRFEGHVGMYVHDLATVVFTAVKHTADWFLASYKEVASCFIEWAKGEMETYAEMFRKQVYSDQKTIDEALKITYAQSRKL-LQ Tapde11 ELDSFFQSLTNTALQNNVYHNYREFISVSKEISTLESDMASIRGLLNDRNSIIDFNLKALWTQVEGAQKFLPADEGRRIVREDKVHMVLLNDHLLLARLVAQRCFPLPEIKMSAVSISVIEKFVFKADSQD--EKQAMYLAFNREVWVQERMDDLDQRIAHREYREAVVLRGRALVLAGMLVSYLVA-IDDAARDTFLAARSALIRKRARGVMFEGDLSLYIADLALVHFTLIRNTTTIYRTSFTSEMSGLVAWAKTEVEAFVDLFVRQLYGDSVVYRDALDAVSKQI-AV-LR Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 EKKRFVAALSAKELQRNVFKNYAEFVTISKEISTLENDMLELKELLAQRNSVADLQITNLWSTVEGSQKYLPIVPGRHLVFEQSVSLFLLSDLLLIARMVAERCWVLADLVVLTNALKIKEVCIYRTSRPE--DKKALLAAFRQVSWVDEYGDDLTMAIATRDWPEALVDKGNDLLLITQIVSYLTK-LDDLARDTFLKARRDVMLKRVRGIKCEGDISVYISELAVVCFTIVRHTSEWYRAAFEDMASGFVTWAKAQIETFADMFRRQVYADGNVAEECLKVTASHNRKL-LR Trire2 QIQEYMESLAAADLQQNLLQNRTQFIKISKEAEKLKGEMRALRNLMSERSSVADRSMQTLYKTVEGSQKFLPNAIGRHVVLNRAMQIFLLNDHLLIAKLVADRCWPLLDIEVLADAIMVRETFIYRTEKPEASEKKALMMNVRKAVWVEGQMDELDIDIALQGFEPAVVEKLKALALATIILSWLAR-LGDRAREAYLAARGDTIHKRARQCLFQGDLHLYIWQLSFVYFTLIHNTVQCFQSCFPPMMSTCVKWAKEQVEAFNVILARQLSSGGPEWTKCMDQAKEHA-KK-LS Umbra1 QLRAFYRSLVGSDLQRNVYRNYTEFVVISKEISNLDGDMLLLRDFLNEEMATADMQLASLWESIEGSQRLLPFAPDRHIVRDQATQLVLLNDCILVAKLVADRCWELDKILVLTNALKIVDEYLFRCERPE--DKMSLLVTIKRVTWLSELPDELEVFIAIREFEDAVIEKARAILLSKAIVNWLLR-LGETGREMFLATRSGVIKRRIRQLTFEGDVTTYINELSLVVFTLVRNTCEWYRDSFKDMASGFITWVKEQITIYAQIFNKQVFGNLRVISDCLRSTAEQC-SL-LR Ustma22 SLRQFKSSLANDDLKRQVFKNYSEFITISKEIATLENDMLELKELLSERNSTIDLQITSLWEGIEGSQKFLPYVPGRHLIAEQSVALFLLDDLLLIARLVAERCFSLAEIVVLTNAIKIKETHVYRTDRAE--DKRALLNAFRRVAWNNDFADELSVCIALREWDQAVIEKGRAVLLVSAIASYLLR-LDEKARQLFLDARTESLKKRTRQIKFEGDTGLYISELAMVHFALIKNTSEWYMAAFKDMASGFVEWASERVEEYAVLFRRQVFGNAEMVSEMREISLRLA-TQ-LN Walse1 EVAHFKQALTNTQLEQSAFKNYSDFISISKEIGSLETEVLELRELLNERSSIADLALQTLHSTVEGSLKHVPHAPGRHIVMTQSVEIVLLNDTLLIAKLIADRAWSFSDITIVKNAIKVKQSYVYMADSPN--DKSVLLNAVKRVVWMEDYVDELSVSVALNDYGTAVIDKGRKLLLVKDLVALLHR-LGSLAKETYFNSRKELIRRRSRQMVFDGDVVNYLAELAAITFTIIKQSAEWFRAAFNSKANGFGYWASEQIKTFATMFKRQISADKDVIERAIEITKEQGLKVSLS Zygro1 EIDRFTSSLVQEEAKENINKSYSEILTVNNDLRVASSELKHLRLSIKERSSVAILELTELFKSVEGSQKHLSPKPGRHILMEQNVHIFILNDTVLVADLVVSQCAPLRDVSALTFTFGSNKC-LYQSRDSK--ECARLLNIFRRAKVLDDLLEEIEIDLERLKFDKAVLIDLESQLICQKLVKNMVK-MGEESLDAFLQNRSNLIQSLILQIGSVDNPTNYLTQIAVIRFQTIKKTVKNFRDIFQEFSSILVNWCKDEADEHFKLIDKQLLNDEMLSPVSIRSSRKQI-DG-LK [Cluster3190.fasta_al_trimmed; alignment length = 235] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 EGELRRLREERDQFETQYNLLSRLSSMKKESQLELENTQEQLSEYERQNATLKTRLEQEMASLNAECETLKAKLSQAQQ-RNLQSRIEELTLEEQTKAYQQQLEQAELNTQLESLVSENERALRLRSQIDAMSADAALEQECKERVLQIGKLRHEAVILNEHLTKALAMIKHKELISNLFISFVSIPRGDPKKFEVLELISSFLSWDDEKKTQAGLM-DSFVSLWAEFLERESEK Aspfu1 QRKLDDAETKKEHAETQFQLLERVNTIKKEDAEELAQANSKIEELEQQNSCLRDNLDADIERKSNEIVTLLQQESYLQAMHNWEILAMEERLEEQLVALKDSYEKDGLQRALQEIQSARKQELRAESALQAAQKELEREKEVKEKNLLIGKLRHEAVTLNDHLTKALRFLKKRHIVTNHLLQFLALDRSDPKKFQILQLIAALLGWTDEQREQAGLARESLAELWSNFLEQE-SQ Aurde31 QAELQRTKAEKEALEEKYRLVERVTTLRKQDAEALKQREEELAQRDAEVDELRSTVDTDSEQSARELERIERELRETQDRDEWERTALEERLRRDLELEREGRERANLQSVLEDFQSVKEHEIKAEVALEDLNNNARRETELKEKNALIGKLRYDSVVLNEHLTEALRRLRKRRLVTNILLSFLTTPRADSKRFEMLQLLSSILSWNDAEREKAGLQRESFSKMWVEFLLKEAAQ Batde5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 EEELERTKEEKESLATQYRLLAKLTTMRKQDAEELDRREQLVQSLTAQNEDLESTVETEAERASREIEAMEREIHELRERDESERALLEERLEGELEALREENARINLQSVLEDFQAGKEVELQAEAELDSSQTNNKREKEVKEKNLLIGKVRHEAVILNEHLTEALRRLRKRRLVTNILLQFLNTPRADAKRFEMLTLLASILSWSDAEREKAGLQRETFSQMWVEFLLKEANQ Botci1 RAELEETESSRENWESQYHLLTRVNTIKKADKEELAEANEKIEDLESQVESFQSTIQGELNESSKELSSMLQQAKHLKAMGDWEVLAMEERMEEQFSAQKEAYETDGLQRALQEIQETRRRELRAETSKEALQTELNREKEVKEKNLLIGKLRHEAIVINDHLTKALRFIRKRQVVTNHFLHFLSLDRSDPKKFQVLQVIASLLNWTDEQKEQAGLARESLSELWTGFLEKSAEE Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 LEKLQQTERERDEIQQSYDLVNKISSMKKQSEAELEEKTELVESLTSENEELKRQLQDQNTDLNNECERLNSTLQALQKVQELNSEINDLKYTNAIEELTDKLALEDFQALVSLKQSNFDKETTSQQELLELKEEVKKKSEIHNKQLSIGKLRHEAIILNEHLTKALSMLRQKELISNVLISFLQFPRGDTKKFEALGLIGALLEWDESQKLAAGLTHQSFVSLWTEFLEKESSG Cangl --------TERDQVESQYQLLSRLSSMKKESEAELEVVKEQLQEYENQNLNLKNKVSLELESLESEQESNQTRIKELEENEQLNSQVQELLSKEEIEDLKQNVENNDMELQLDAVEKANKEQLDLEKKLAAMKQDVTLEKESKEHASQIAKLRHETIVLNEHLTKALAMLKQKELISNLLISFVSIPRADPRKFEVLELLSNFLNWDDDQKRQAGLIFESFVAMWTDFLERESEK Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 REELDEANEGKEHFETQYKLLGRVNTIKKADAARIEEFETQVADLEDQNRELQEHNNSEKEAQASEIETLISREAYAKAMQDWEVLAMNERLREQLESIKDEYEKEGLQKALQEVQNLRKAELKAKAALESTKKDLEREKEVKEKNLLIGKLRHEAVTLNEHLTKALRILKKRQIITNYFLHFLSIDRSDPKKFEALQLISALLGWTDEQKEQAGLARESLAELWQDFLEREAAE Coere1 SDELKRLRAEANQLQARFQ------SERRKELDEVRR--------------------TAIKGYEQQIAELEERIELLQSESQW----------------------QNLQSALESLQVSKDADVDAEGRLRKIELSGATQQKITDQMSEIERLRHEVAVLKDHLNESMYRLREKRVITNLVVGFLALSYGDPKRYEILQLMSSILQFSEEQQEKVGLIRDSFSDQWISFLLRESSK Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 RRDLDAEREAKKSLEAQYQLVSKLTTMRKQDAEELDRREQLVQQLTAQNEDLATAVETEGERTARELDSIERELHETVERDEWEQAAMQERARRDLELEREARERANLQSVLEDFQAAKEHELDAEVRLEENTSNASREKDVKEKNLLIGKLRHEAVIINEHLMEALRRLRRRRLVTNVLLSFLTTPRADSKRFEMLSLLSTILQWSDAEREKAGLQRESFSRLWVEFLLTEANQ Copci QKELEKTREEKDALAEQYNLLARLTDMRQQDAEELDRREQLIQTLTAQNDDLTATLETEADRTSRELDALERELREAQERDEWERMAMQEKLQRDLDLEREARERANLQSVLLDFQSAKEHELKAELKLEENNTDITREKELKEKNLLIGKLRHEAVIINEHLVEALRRLRKRRLVTNVVLSFLTTPRADSKRFEMLNLLASILQWTDSEREKAGLQRESFSRLWVEFLLTE-AS Croqu1 QQQLESLRTEKATLEGQYGLLGKLTTMRRQDADELDRREQQIAQLQAQNEDLHQGLEADTERLQRELTHLEEAYRECRDLEDKKRELMNESMSRDLQLLKEDRDNANLQSVLEEFQAAKDSEIRAETKLAATQSDTALKKELKEKNILIGKIRHEAVILNEHLTEALRRLRRSRLVTNVLLSFITTPRADTKRFEMLALLASILSWNDDQRQQVGLQKDTFTDQWVSFLLREANS CryneH991 EDDLEATRQEKEAL-GKTDCFGRI-------QEELDRRETQINNLVTENSELHETVDTESSHLSAQLAQLTREMRELREREEWEVEAGRERFERREQDMCNALEKDNLQEVLSEFQAAKDSEIRAETRLSEVSSDASKEKELKDKNQIIGKLRHDAVVSNEHLKEALRRLRKRRLVTNILLSFLMTSRGDPKRFEMLSLLATILSWDDAEREKAGLQRESFSNLFVEFLLKEASQ Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 EDQLSKVEKERDETKSSYDLLSKLSSMKKESQRELEETKETLEALTTENSDLKEKNQTESSDLNNECDRLQSKDESLLKINELKLELNEITLNLTIDELKDKLQSSIHTQSISERDLEIESLKQKITKVSQLETENEKEADVNSKQLIIGKLRHEAIILNEHLTKSLTMLKQKELISNVVISFLQFPRGDTKKFEALQLISALLEWDESQKVSAGLSHQSFVSLWTDFLEKESEK Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi SKEYSLILKEKNNEISDLKLKSSLISPKKDDNNNNNILKE---QFEKNKEDYQNQILSKIEQLEQKISTLSSTINELNEKQQTENIEQQTQLKEQVNKSNKELARQNINNQLMNEQIIKDEQLRLEQKLEQNNKEIESKYSIAQDQLLYQDIQSKTIKLKEDIEPTILRLGDKRVVSKLFLNYFS----GNKKTEILELIAKILNFSDAEKISIGLTKKPLAEMWIEFLLKESSG Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi EEKIKKMTEEKKQIEEVKRLILKQEEAQQKNTQVIEKQKEEIEEVKQENKELQKSIEREIEKQKKIIQTLGRKMKEDQ-------------LEEELEQIKKENQR--------------NEELN---------------DEIKQLNETITKLYEE----NETLKKTVENFTQKRIVNKLLISYITKPH---QRMEIVNLMSKIMDFTDEEKRLLGLSQKTFGDLWVEFLLRESGS Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 --------------------------MRREESEELDRRQQIIDQLTAQNEDLTATVETEAERASKELEAMERELRELQERDEWEREAQEGRYKRDLEIEREARQKMNLQSVLEDFQNTKDHELRAELQLEETSTNTTREKEVKEKELLIRKFRHEAVILNEHLTEALRRLRKRRLVTNVLLQFLTTPRADSKRFEMLGLLATILSWGDAEREKAGLQRESFSQRWVEFLLKESSG Fusgr1 KSDLEESNAAKENAEEEYQLLGRVEKIKKRDKAELEESKERIEELEAENEELRNNAVSELQDATRELNTLLRHVQHLKAMGEWEVIAMEERLEEQVTLLRQNYESENLQNALREIQDARKKELRAETAKQTLTQELEREKEVKEKNLLIGKLRHEAIVLNDHLTKALRYLKKRQIVTNHLLHFLTLDRGDAKRFQVLQVMAGYLNWTDEQREQAGLARESLSELWANFLERSAQE Galma1 QRELDRTKDEKDTLATQYRLLAKLTQMRQQDAEELDRREQLVQQLTAEKDDLTATVETEAERASSKLDAMERELRETQERDEWERSALQEQLRRDLEVEKVTRARENLQSVLQDFQAAKDHELRAELQLEESHTNITREKEIKDKKLLIDKLRHEAVIINEHLMEALRRLRRRRLVTNVLLSFLTTPRADSKRFEMLSLLASILSWNDPEREKAGLQRESFSRLWVEFLLTEAAS Ganpr1 RAKVDTEREEAKAAVRQYRVVVKVESERARLRNELERAGQEVVELSQNVDTAVEEVARDVQRLESEVEGAEGELRATKARGRWEVEVERVRLRRLLQTVDDERAKTELSSLVEGLQRQKEDDLALSARVASLTDDLGALSEANARSAEVDKLRKELARLREHLVEALAAMKARRLISNLVLNFLQMPRGDGKRFEMLTVIGGILNWGDEEKFKAGLTRESFTDMWVAFLQREAER Gloin1 ESQLEQSKEEKKQLEVQHQLIAKLANFKKADNEEHNRIRQQYNELNEQNKELNNTILQENDKVNHQLESLDDIIRDLQEREEWEVNAMELKLEREMDALKHEKEVANLQNVLEEFEAAKQSEIRAETQLAQIKDEIGKEKEIKEKNLLIGKLRHEAVILNGHLTEALRRMREKRLITNLLIAFFNTPRGDSKRFEILQLMANMLEWTEEQKEQVGLIRESFSDMWISFLLKEASK Hisca1 QNELKQSQNDKEHAETQFRLLGKVNTIKKADAEELEQKRSRIEELEGKNAVLQTEVESEREQQSKELSSLVERESYARAMHNWEILAMEERLEEQLVTLKSDYEKDGLQRALQDIQSARKQELRAIAKLEEAEAELKREKEVKEKNLLIGKLRHEAVTLNEHLTKALRFLKKRHLVTNHFLHFLALDRSDPKKFQVLQLIAALLGWTDEQREQAGLARESLAELWSNFLEQEAAQ Klula1 ENDLQRVKEERDQYELKYNLLSKISSMKKQAQQELENTREQLNEYENQNINLKQKLKSEIVNLNKECENLKSKIKELEEVKSLKSQIDNLELEEQIADYKQQLEQSNLEKQINDNNTTIETLTKLRAKVASMSEDVALEREVKERVLQIGKLRHEAIILNEHLTKALAMLKQKELISNLFISFVTIPRGDPKKFEVLELISSFLNWDTDKKTQAGLI-QNFVSLWTEFLEKESEK Lacbi2 QRELEQTREEKETLATQYRLLAKLTQMRKQDAEELDRREQLIQQLTTQNEDLLSTVETEADRAQIELDAMERELREAQERDEWERTALHEKLTRDLELEIEARERENLQSVLQDFQSDKDRELRAELQLEESNTNIIREKEVKEKTFLIGKLRHEAVILNEHLMEALRRLRRRRLVTNVLLSFLNTPRADGKRFEMLSLLSSILSWSEQEREKAGLQRESFSRLWVEFLLTEAAA Lenti61 EQELQRTREEKDTLATQYRLLAKLTTMRKQDAEELDRQEQLVQQLTAQNDDLAATVETEAERASRELETMERELHELQERDEWEQKALQEHLRRDLEVEREARQRGNLQSVLEDFQASKEHDLKAELQLEESSSSNSREKEVKEKSILIGKLRQEAVIINEHLMEALRRLRRRRLVTNVLLSFLTTPRADPKRFEMLSLMSTILSWSDDEREKAGLQRESFSRLWVEFLLTEAAS Malgl1 --------------------------MK------------------------------------------QATLRN--------------------------------------------------------------EQEMKERNIIIGKLRHEAVILNEHLKNALSRLRRRRLMSNLILQFLSMPRADTKRYEILRLIASILQWDDAEREKAGLQRESVSNLFVEFLLSEVER Mellp23 QQQLESLRAEKSTLEGQYGLLGKLTTMRRQDADELDRREQQISQLQIQNEELHSGLESEQERLEKEIHQLEEVYRESRQLEDSKRDLVLESMSNDLKLLKEDRDMSNLQSVLEEFQAAKDSEISAEAKLAATQSDTVLKKELKEKNILIGKIRHEAVILNEHLTEALRRLRRRRLVTNVLLSFITTPRADTKRFEMLSLLATILSWNDDQRQQVGLQKDTFTDQWVSFLLREANS Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KEDLQKTTNERNHFQTQHKLLDRVSNMKQADMDNINTLRQQIDQLTAQNNDYLLTIKQHYEKTSRELEHLENLIHELQEREDWETMASEQRMERERDAARAEKEANNLQSVLEEFQSAKESEIQAEEQLQNLTLDVEREREVKEKNLTIGKLRHDAVIQQGHLTEAMRRLREIPLISNLFISFLNIPRGDQKRFEILQLISGVLKFTDEQREQAGLIRVCFRQEYVNVLL----- Mucci2 --------------------------------------------------------------------------------------------------------------------------MQAEAALAKYQQDVGKEQEIKEKNLLIGKLRHEAIILNEHLVEAMRKLKERQLITNLLVGFLMAPRGDRKRYDILTIISNVLQLTEEQKEQIGLSRESFTDAWISFLLKESSP Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RSDLEESEAAKEHAETQYQLLDRVEKIKKRDRA-------RVEELETANEELQQAAQTQVDEQARELDSLEREVEHIRAMGEWEVIAMEERLEEQLANVREAYERDGLQRALQEIQEARKRELRAQDARESLQKELEREKEVKEKNLLIGKLRHEAIVLNDHLTKALKYIKKRQIVTNHLLQFLSLDRSDPKKFQILQVIAGLLNWTDEQREQAGLARESLADLWAGFLERSVEE Orpsp11 ------------------------------------KLREMVTSLNEENESLTSQVEKQIDKLNRELTKLENKINEYKKLEEWKDITSHERLQKEAEALREESENSNLQLVLEQFQASKEADIQVEGKLGN--ANELDQKELQEKNELVGKLRRNVVQYQSHLADAMRHIKA--------------------------------------------------------------- Pench1 QQKLDDAENKKEQAETQFQLLERVNTIKKEDAEELALARSQIEDLEDENNNLKDELNSDSAEKEKELSTLLEQESYLQAMHNWEILAMEERLEEQLSSLRDGYERDGLQRALQEIQLARKQELRADKALQNAKEEIEREKEVKEKNLLIGKLRHEAVTLNDHLTKALRFLKKRHIVTNHFLHFLALDRSDPKKFQILQLIAALLGWNDEQREQAGLARETLAELWSNFLEQE-AE Phybl2 ---------------------------------------------------------------------------------------MEE---------------ANLQTVLEEFQATKDAEIRAEASLEQYQHDVAKEQEIKEKGLLIGKLRHEAIILNEHLVEAMRRLKERQLVTSLLVGFLIAPRGDRKRYDILTILASVLQLSTEQKEQIGLIRESFTDAWISFLLKESN- Picst3 SDKLAAAIDERDEIQRSYDLLGRLQSVKKVAESELEETKDTLALAVDENASLKEKIQVQNEDLNGECDRLQLQLEELQKINELKVEISEFNSLLKIEELNDKITGKELERANNEKQLAFNSAEVAQEQIEQLKVESKEKVEINNKQLIIGKLRHEAIILNEHLTKSLTMLKQKELISNVVISFLQFPRGDTKKFEALQLISALLEWSESQRVAAGLSHQSFVNLWTDFLEKESSG Plicr1 QRELERTKEEKDKLAAQYQLLAKLTTMRKQDAEELDRREQLVQQLTAQNDDLSSTLEADIERASSERDTLERELREA-ERDEWERAALGAELRRELELEREGREKANLQAVLEDFQAAKEHEMRAEMRLEELDTSSSREKEVSQNNHLISKLRHEAVILNEHLTEALRRLRRRRLVTNIVLQFLAADRADPKRFEMLALLAGVLGWGEAERARAGLVRESFSRLWVEFLLTEAAS Polpo TKEFSRLMSEKETELTDLRLKQTLMSP---NNNENDTLQSLQIKLKKQSENYQSQISTQIETLQQEIEHI----DQLKEKEEKEKESEKQDLKKEIEQLNEELTK-NNNNSSDKQQELDDKRLT-ESQLPRGKRHHQA----SQHQ-------------GEGIS-----LSDKRIVSKLFLTYFNV--KGTKKLDVLELIAKILSFNDDEKVTIGLTKKSLTDMWIEFLLKEA-- Pucgr2 ELQQETLRNEKATLEAQYGLLAKLTTMRRQDADELDRREQQICQLQAQNEELILTTENETERLHDELGQIEEAYRESQQLEDSKREIMNEALKRELEFVKEDRDLSNLQSVLEEFQSAKESEIQAEAKLAASESGAAQKKEIKEKNLLVGKLRHEAVILNEHLTEALRRLRKRRLVTNVLISFILTPREDTKRFEMLSLLSSILSWNEDQREQVGLQRDTITDQWVSFLLREANS Punst1 RQELARVREEKDELDTKYQLLTKLNQMRKQDAEELDRREQLLQQLNAENEDLAATVETESERHARELDRIERELRETQEREEWEREAAQGRFRKEWEMEREAHNRANLQSVLEDFQSAKDREIRAEMRIEETSTDTSLQRKLKEKEVLTEKLRHEAVIINEHLLEALRRLRKRRLVTNIVLQYITTPRGDSKRYEMLSLLATILSWNDAERERAGLQRESFSKLWVEFLLTEANS Rhior3 KSKLEESEEKRSLLNKEHQLLGKLSHIKE----QDKQLREKINELTH-----------ERES--------EREIESITKCEEYEAVAMDLDTQTELEALKMKTAAANLQTVLEEFQATKDAEMQAEGALEKYKNGVEKEKEVKEKNLLIGKLRHEAIILNEHLVEAMRKLKE----------FLNTPRGDRKKYDILTIISNVLHLSEEEKEQIGLSRESFTDAWISFLLKESNP Rhoto1 EDELDRTRMDRDAWEAQYQLLAKLTAMRKQDADELDRREQEIADLRAANDDLSTTLETDADALHSEVEQLELALREAQERDEWEQEAMRERAKAEREVLREERDRANLHAVLEEFQAAKDNELQAETQLQNAQNDSEKAQEVKEKNLLIGKLRHEAVILNEHLTEALRRLKKRRLVSNVLITFLNTPRGDAKRFEMLQLIASILSWTDDQREKVGLQRESFSNLWIEFLLKEAST Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 KNELANVIKERDEFKTQYDLLSKISSMKKEAQKQLEEVQEQLTEYESQNLKLKKKLEAELENLEKEQESTESRIEALEEKDQLNLQVQELMLRTERDELRQALESNDLELKIEEVDNKREEEARMKKQLEAMKEDASMEEESKQHILQIGKLRHEAIILNEHLTKALAMLKKKELISNLLISFVSIPRADPRKFEVLELLSNFLNWDEDKKQQAGLI-ESFVSLWTNYLEKESEK Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 QQELQRTREEKEALAGQYRLLAKLQTMRQKDAEELDRREQQIQQLSAQSEEFAATIEAEAARLSNELSDLERELRETQERDEWERVALQERVKREIERERELSERANLQSVLQDFQAAKDHELKAELKLEENASNTSREKEVKEKTILINKLRHEAVIMNEHLTESLRRLRARRLVTNVLLSFITTPREDSKRFEMLGLLATILGWSDAERVKAGLQRESFSRLWVEFLLTETSS Schpo1 EEAYQTLKNSYNSLKQQHSLLGKVSGIKKKDSQELAQNRKRIQELEKSLGDAEEALKLQVESLTQDITDLENQLLSTQ---QWERRARDEHCEEQLARETERQEQHQLEIELESTKASHTENLGLQNELDATQKRLSREHEVKEKTLLIGKLQHEAVVLNEHLTKALCMLKDKQLISNLFVSFLTLPRADTKRFEILQLISSVLDWNDTQREQTGLQRHSFSKR----------- Sorma RSDLEESEAAKEHAETQYQLLGRVEKIKKRDRA-------RVEELETANEELQQAAQTQLAEQAREIDGLEHEVEHLRAMGEWEVIAMEERLEEQLANVREAYERDGLQRALQEIQEARKRELRAQDARESLQKELEREKEVKEKNLLIGKLRHEAIVLNDHLTKALKYIKKRQI--------------------ILQVIAGLLNWTDEQREQAGLARESLADLWAGFLERSVEE Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 SERVEQVRAENEQIKAEYELMDKLTTMKQAELETSQKLRQEVQLLSQENEALQNQLAQRIGRLERELDRLETVIKEYIDREQWEEAAAQERMHETMETIKQDMERSNLQRVLEEFQISKEREIAAEERLEKIGMDAPSQAELQEKNVVIGKLRHDVIQLQAHLSEAMRRMRDRRLITNLLVSFLSAPRGDTKRFEILSVISSVLKFEEEEKVRVGLVRESFTDMWISFLLKESSK Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 QQELERTRQEREEFASQYRLLARLNTMRKQDAEELDRREQTIQSLTAQNEDLSLTLETESDRLSSELSEFERELRDRDERDEWERACLEERMRREVEGGRERVGRANLQGVLEDFQSAKDHELRAELQLEESTTNTSREKEIKEKNLLISKLRHEAVIINEHLMEALRRLRRRRLVTNVLLSFLSTPRADPKRFEMLNLIATILSWNENERMKAGLQRESFSRLWVEFLLTEANA Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ESQLLAVRQEKDVLQAQYRLLGKLTAMRKEDAEELDRRENTINSLTTDNATLQNTISTESQNLQNQIQQLTREMRELREREEWETEASKERLERRERDMRREWERRNLQEVLGEFQAAKDSELRAETRLSEVSNDALRELDVREKNKTIAKLRHEAVVNNEHLTEALRRLRKRRLVTNILLSFLTTSRHDSKRFEMLSILSTILSWDDTEREKAGLQRQSFSNLFVEFLLKEASQ Trire2 QSELEDSNAARETAEEQYQLLGRVEKIKKRDKAELEEAKEYIEQLEAQNEELRSAAEAELQDATRELTTLLKTIQHLKAMGEWEVIAMEERLEEEIASLREGFEADNLQNALREIQDARKKELRAQAAKEELVKELEREKEVKEKNLLIGKLRHEAIVLNDHLTKALRYLKKRQVITNHLLHFLTLDRGDAKRFQVLQVMAGYLNWTDEQREQAGLARESLAELWAGFLERSAQE Umbra1 NSK--------NHLEKEHNLLEKLSAMKQANQDENKKLRENNAEL-------------ECENLHAENNHLEKELNGLKEREEWELRAMEESAMKDVERTEEELRTTNLQAVLEEFQTSKELEIRA----EQFHRDVEREQEIKEKNLLIGKLRHEAIILNEHLVEAMKRIKERQLITNLLVGFLIAPRGDRKRYDILNVIASVLQLSDEHKEQIGLIRESFSDAWISFLLKEANR Ustma22 RAELARVREERDTFETQYRLLSKLTTMRRQDAEELDRRETQIETLTSKLSTLETESSTETDRLTREVDTLERELHEL-DSSNWQASCLEERAQQEVERAQQSESHANLSIVLAEFQSTQESELAAESKCKQNADLASQSAQVKEKNLLIGKLRHEAVILNEHLTEALRRLRNKRLVTNLLISFLTTPRTDGKRYEMLNLIAGVLGWKEEERELAGLQKESFSNLFVEFLLSEAES Walse1 LSELKQVKADKLKLEGQYRLLGKLSSMRKEDAEELDRREVQINALTETNDKQTAKVAERNAQLSNDLSTLQSRLRDLEEREEWQSQADEEHLLEELETIKNEYKGRNVESLLSESQLSTNS--RTQANLELFRQDAEREQECKEKTLLIGKVRHEAVILNEHLTEALKRLKERQLMSNILLQFVTTPRSDGKRFEMLNLLASILSWNQYEREQAGIAPASFGQLFVEFLLKETGA Zygro1 ESELSKVRAERDEFQSQYNLLSRISSMKKESQNELESVQEQLTAYESQNMKLKQKLDSELSSIEEERETVKKTIDDLQQNSQLNTQLQELLLHQEREDLQFNLENKEMEAELERTEQRFNDQLTLRGEVERMKDAVEQEKECKDRVLQIGKLRHEAIILNEHLTKALAMLKQKELMSNLLISFVAIPRADPRKFEVLELLSSFLNWDDDKKRQAGLILENFVSMWTDYLEKESE- [Cluster3193.fasta_al_trimmed; alignment length = 61] Allma1 G-WWGRG--PHQAQTGIVTYQISPFRQRAFAGAVFNVVRRTTAQAPYPFLIGYSMHTKEGA Ashgo11 G-WWGGS--P--KQKYITSYAVSPYAQKPLAGIVFNTFRRVRAQALYPFGLYYAWYTKAGR Aspfu1 L-LFLGC--P--TPQRIVTYSLSSNRQRPLAGAIFNTFRRFRSQVLYPFVVAYAANSKPGR Aurde31 G-WWGGS--H--GQKHIAVYSISPYKQRAFAGAIFNGYRRIMKHLPYPVSIGYAVQSKAGH Batde5 --WWG----PMSRQVGFYEYGVSPYHLKPLKGVATLFLKRTGKQLLYPVAFFYSICRKAGI Botbo1 G-WWGGG--P--KQKGITQYGLSHFRQRPFAGAIFNGYARIVSQAPYPLGFAYGVQTKEGH Botci1 G-GWGGS--Q--PQKGVASYALSANRQRPLAGAIFNTWRRFRGQVLYPFIIAYTANSKPGR Caeel ------------------------------------------------------------- Canalb1 G-WWGGS--P--KQKYITQYTISPYAAKPLKGAVFNTFRRTKNQFLYPFVVVWSIYTKEGR Cangl G-WWGGS--P--KQKGITSYSVSPYAQKPLAHSVFNTFRRVKSQALYPAGIYYYWYTKAGR Capow ------------------------------------------------------------- Catan2 G-WWGGG--KHQAQNNITTYQISPFRQRAFAGAVHNVFRRTMAQAPYPVAFGYYVHTKEGH Cioin ------------------------------------------------------------- CocheC53 G-AWGGG--R--PGKGIVTYQLSPNRQRPMAHFFWNVVRRSKNQVLYPLVLGYGANSKPGR Coere1 G-WWGGG--P--KHRGVVTYQLSPYEMKTNAHLTHNFFRRTSSQLGYGVFLFWAVNSKAGH Conco1 G-WWGGG--P--TQRGIVSYTLSPYEQKAFAGAFFNVVRRVSAQVPYGIAFGYTVQSKAG- Conpu1 P-WWGSM--A--RQRGVITYSVSPFRQRGSKDLVFNGYRRLAGQVPYPFAIGYGTNSKAGH Copci L-WWGGT--L--RQKGITTYTISPYQTKTAPHWLFNFYRRIGGELLFPFALGYATNSKAGH Croqu1 G-WWGGG--P--KQKGIVQYAISPYRQSPMKNVLFQGYRRIIVQVPYPFAAAYGINSKAGH CryneH991 -----GR--A--EYSSVFSPGLSPYRQRPLAGMVFNGSRRTMQQLPYPLMFFYGVNSKQGH Crypa2 GHGWGGTPVQ--KQKGIVTYGLAPNRQNPFAGAVFNTWRRFSSQVLYPFIAAYFVNSKAGI Debha1 G-WWGGS--P--KQKYVTTYTVSPYATKPLKGAVFNVFRRVKNQTLFPAVIVWNVYTKAGR Dekbr2 G-WWGGS--P--KQKYIAQYTVSPYAQSPLKGSVFSTFSRFKSQVFYPLCIVYGFYTKAGR Dicdi ------------------------------------------------------------- Dmel ------------------------------------------------------------- Enthi ------------------------------------------------------------- Falba ------------------------------------------------------------- Fomme1 G-WWGGG--P--KQKGIIQYAVSSTRQAPMRDALFSGFWRIAGHLPFPFAIGYAITSKAGH Fusgr1 G-NWGGG--E--KQRGIITYGLSANRQNPWAGSIFNTFRRTKGQIFFPMVAGYWMNSKAGR Galma1 --------------------AISPFQTKAAPHWVFNGYRRLSGEILFPFAVGYGVNSKAGH Ganpr1 --NWGNN-LP---HMGIKSYAISPFRQRPFAGLIYNTYRRFVAQVPYALLLYFAVRSKISA Gloin1 --WWGGG--P--VQKGIVTYSVSSFQQRAFAGAIFNVFRRTMSQAPYPIIFGYLIHSKAGK Hisca1 G-TFGGC--P--TPQKISTYALSPNRQRPFAGAIFNTWRRSRNQALYPFVAAYALNSKAGR Klula1 G-WWGGS--P--AQKGITTYTVSPYAQKPLNNIVFNTFRRVKSQILYPAALYWAWYTKAGR Lacbi2 L-WWGGG--V--RLKGITQYTLSPYQVKAAPHWLFNGYRRLSGELFFPFVLGYSVNSKAGH Lenti61 L-WWGGV--Q--KQKGVITYGVSPFRQRAAKNMLFNGYRRLSSQLVYPFAFGYGTNSKAAH Malgl1 G-WWGGG--P--AQKGIKTYSVSPFQQNPFAGVMFNGFRRAVKHMPYPFLVGYFINSKEGH Mellp23 G-WWGGG--P--KQKGIVQYAISPYRQSPMKNVLFQGYRRIVVQVPYPFAAAYGLNTKAGH Mnele ------------------------------------------------------------- Monbr ------------------------------------------------------------- Morel2 G-WWGGA--P--KQRGIVTYTLSPFEQRAFAGAIFNTFRRVTGQAFYPLGAAYGILSKAGH Mucci2 G-WWGGG--P--TQRGVVTYILSPFEQKAFAGAVFNTARRVTSQVPYAFGLGYFISS---- Mydma ------------------------------------------------------------- Neucr2 G-GWGGG--M--KQRGIISYGISPNRQNPLAGTVFNTFRRVSSQFLYSLVAGYYINSKAGR Orpsp11 ------------------------------------------------------------- Pench1 G-NWGGC--P--TPQRVATYSLSPNRQRVLAGAIFNVFRRFRHQVLYPFVVAYAANSKPGR Phybl2 G-TWGGG--P--TQRGVVTYILSPFEQKPFAGAVFNTSRRVASQIPYAFALGYYITSKAGH Picst3 G-WWGGS--P--KQKFITIYTVSPWATKPFKGAVFNTFRRTKNQALYPFAIVWNIYTKAGR Plicr1 F-WWGGT--I--RQKGVVQYTLSPFRQRATKGILFNGYRRIASQAPYPFAAGYGINSKEGH Polpo ------------------------------------------------------------- Pucgr2 G-WWGGG--P--KQKGIVEYSLSPYRQSPMKNALFQGYRRLAAQVPYPFGVAYGVNTKAGH Punst1 L-WWGGG--Q--RQKGIVQYSVSPFRLRAFKHLLFNGYRRIAAQAPYPFAAGYGIRSKDGH Rhior3 G-WWGGG--P--TQRGVTTYVLSPFEQKPFAGAVFNTARRVASQVPYAFGLGYYILSKAGH Rhoto1 G-WWGGG--P--TQKGISQYVVSPFRQAPMRGALHNGVRRLGQQAVYPFAAAYGINSKHGQ Rozal11 ------------------------------------------------------------- Sacce1 G-WWGGG--P--KQKGITSYAVSPYAQKPLQGIVFNSFRRFKSQFLYPAGIYWYWYSKAGR Salro ------------------------------------------------------------- Schco3 P-WWGPI--K--KQKGIGAYTISPYQSKAAPNMIFNAYRRLSGEAFFPFAIGYGTNSKAGH Schpo1 G-WWGGG--P--KQKGIITYSLSPFQQRPMAGFTQNMFRRVMTEGLYPFGIAYYINSKHGR Sorma G-GWGGG--M--KQKGIISYGISPNRQNPLAGTVFNTFRRVSSQFLYSLVAGYYINSKAGR Sphar ------------------------------------------------------------- Spipu1 ------------------------------------------------------------- Sporo1 ------------------------------------------------------------- Stehi1 P-WWGGI--Q--KIRGVTTYTVSPFRQRAASHMLFNGYRRLSKQFIFPVAVGYSTSSKEGH Tapde11 ------------------------------------------------------------- Thetr ------------------------------------------------------------- Treme1 G-WWGGG--P--KQKGVIQYSLSPFRQRATAGMLFNGFSRIMAQVPYPFAIGYGVNSKEGH Trire2 G-DWGGG--A--KQKGVVTFGLSANRQNPFAGAIFNTFRRTKSQIFYPMLAGYYLNSKAGR Umbra1 G-WWGGG--P--KQKGITTYALSPFEQKPFAGVIFNTSRRVSAQIPYAFGIGYGILSKAGH Ustma22 G-WWGGG--P--TQRGIVQYSVSPFQQNAMKGAIFYGFKRIMQQAPYPFGFGYGLNSKAGH Walse1 G-WWGGS--P--KQRGITQYGVSAFTQRPFAGAIFNGYKRLAKQLPYPFALGYGINSKAGH Zygro1 G-WWGGS--P--AQKGITSYSVSPYAQKPLAGIFYNTARRVGAQALYPMGIYWTWYTKAGR [Cluster3209.fasta_al_trimmed; alignment length = 97] Allma1 LHLLGVNLPDRKKVPFFGVGRKLGEQICHQLSIHKLQDLTDAQINQLGMTLEGDLKREIKNRVRQIGTVTGKKFELGLPVRGQRTRTNARTANKLNR Ashgo11 VHVLGKAFKGKEVVRFYGIGLKTSERLCAKLGLYRMQSLTEPQIMAMSMTIEDDARAIVKENIRRIGSYAGLRHAMGLPVNGQRTRTNAKTARKLNR Aspfu1 VFILGVNFPERNLVKFFGVGPQVSARLLARFHIHKVGELANKQVLDLTMKIENDLRRQILDDIKESGSYRGRRHALGLPVRGQRTRTQASSVCALSS Aurde31 VFILGTLLPDAHCVHFYGVGPVVSSRICARFQIHKVSQLSQQQIVGLQMRFEGELRRTMRENIKNIGSYVGRRHATGLPVRGQNTRNNAVTARKLNR Batde5 LYLLGVNLPDEKLVHVYGVGRKTGEQICHKLLIHRLKDLPESKVTQLSMTIEAELRRQTEENIVDMGTYRGMRHKAGLPVNGQRTRSNASTAKRLNG Botbo1 MIILGRNLPDHKALKFYGIGLHTSERLLARLQIHKVNSLTQTQLTNLTIKIESELRREIRENIRMIGSYVGRRHAMGLPVRGQNTRTNAKTAKKLNK Botci1 ------------------------------------------------MPLETELKRRLQDNIRTMGSYRGRRHAMGLPVRGQNTKSQISTARKLNK Caeel ------------------------------------------------------------------------------------------------- Canalb1 VVVFGKSIKHNFPVRIFGIGYQTAERLMAKVGIYRMNQLTEPQIMDLNLLVEGHLKHKINNDIRTIGSYAGSRHALGFPVRGQRTKTNGSTARQLNR Cangl VHILGKAFKGKEVIRFYGVGKSTAERLCSKLGFYRMHQLSEPQILNITMTIEGDARAIVRENIKKIGSYEGMRHALGLPVRGQRTRNNAKTARKINR Capow ------------------------------------------------------------------------------------------------- Catan2 LHLLGVNLPDKKKVPFYGIGRPLGERICHQLSIHKLHELSDAQINQLGMTIEGDLKREVKNRVRQIGTVTGRKFELGLPVRGQRTRTNAETASKLNR Cioin ------------------------------------------------------------------------------------------------- CocheC53 VFINGFSFTEATLVKFYGIGPSVSQRIMAKFHIHKVGSLKNATVMDLTMKIENDLRRQVQDDIRDMGTYRGRRHAMGLPVRGQKTRTQIATARRLNK Coere1 LHLLGVNLPDRKIVLFYGIGPQTARKVCSQLSIHKMNELSETKVNQLSMTLENDLKRKISANVREIGTYVGKRHAMGMPVHGQHTLNNSKTAKKLNR Conco1 VHILGVNLPEQKVVRIYGIGPQTAQTICNQLSIHKLRDLDEVKIIQLTMTIESDLKREVKKNIKNIGCYVGRRHTFGYPVHGQNTRNNAKIAKRLN- Conpu1 ------------------------------------------------------------------------------------------------- Copci VHILGVHLPDNYLARFYGVGQKTAHRLCARFQIHKVKDLSPFQVTSLALKIESELRREIRENIRMIGSYVGRRHAMHLPVRGQNTQSNAATAKKLNR Croqu1 MFVLGVNLPERKLVQYVGIGHYTAKLICNRLQFHTVGDMTEHQIARLSLIIESDLRREVRANIRAVGSYRGKRHALGFPVNGQRTHTNAKTAKKLNR CryneH991 MHLLGHNLPDHKPLKFYGISHALSARLLPRLGIHTVAQLTEPQLTALSLKIETEKRRAMQADIRMVGTYRGRRHAAGYPVHGQRTQTNAKSAKKHNR Crypa2 IFIFGVNFGEKKLVKFFALGTQSADRIMAKYSIFRLEALSPKTIMQLTMPIENDARKVVQNNIRDMGSYRGKRHVMGLPVRGQRARNQNATSARLNR Debha1 VHIFGKSIKHNALVKIFGVGYNTAERICAKVGIYRMNQLTEPQIMAINLTIEGHLKQKILDDIRSIGSIAGSRHAAGLPVRGQRTRNNSQTANRLNR Dekbr2 VHILGKAVKGKARVAFYGIGFNTATRICSKLGFYRVHQLTEQQVMSITMTIESKLLSQIRSNIKDTGSYAGLRHAMGLPVRGQKTRNNAKTARKLNR Dicdi ------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------- Falba MYLQGVVIDKELNIIISGIGQKKAEEICNLCHIHKISELDNQQERRVQMRVGHLLKKETTSDIINNKTYRGYKHLLGLPVKGQRTKTNATTKTHKNS Fomme1 VFVMGINMPDKKLARFYGVGERTADRLCARLQIHRVRNLTQNQITGLTIRIESELKREIRENIRMIGSYVGRRHAMGLPVRGQNTQNNAKNAKKFNR Fusgr1 VFLLGVNFGEQKLVKFYALGPTTSARIMAKYSIHKVGSLAPRTVTSITMTIETDARRLVQENIKDMGSYRGRRHAMGLPVRGQRTRTQTASANRLNR Galma1 VHILGINLPDKQLARIYGVGQHTAHRLCARLQVHKVKDLSPFQVTSLALKIESELRREIRENIRMIGSYVGRRHAMHLPVRGQNTQNNAKTAKKLNR Ganpr1 MFLLGVNVPDGKLARIYGIGASQADAICARLAIHLLRDVPEDTLNRLSRLLESDLKREVRRRIVAIGSQRGHMHERGLPTKGQRTQTNARTAKRRNA Gloin1 ----------------------------------------------------SDLRRQVRNNIRAIGNYKGKRHAMGYPVRGQRTSTNAKTARKLNG Hisca1 VFILGINFPERQLVKFFGIGPLTCNKLMARFYVHKIGDLANKQVLSLTMKIENDLRRQILDDIKDTGTVRGRRHALGLPVRGQNTRSQIKTAIKLNK Klula1 VHILGKGFKGKEIIKFYGIGLKTAEKICSKLGFYRMHQLTEPQVMAITMTIEGDARAIVKENIRSIGSYEGMRHALGLPVRGQRTRNNAKVARRLNK Lacbi2 VHILGVNLPDNHLARFYGIGHKTAHRLCARLQVHKVKDLSPFQVTSLALKIESELRREIRENIRMIGSYVGKRHAMHLPVRGQNTQSNAKTAKKLNQ Lenti61 MHILGVLLPENQLVKFYGIGNKTALRLCARVQIHRVRNLNQSQVTALTIKIESDLRRQMRENIRMIGSYVGRRHAMHLPVRGQNTQSNARTARKLNR Malgl1 MYLLGTYLPDHKLVRFYGISYDTARRLCARIQVHTVSSLTESQITDLSIVLESDLRREVLANIRSIGSYVGKRHAGGFPVRGQRTQRNALTARRLNR Mellp23 MFVLGVNLPERKLVQYVGIGHYTAKLICNRLQFHTV------------LIIESDLRREVRANIRAVGSYRGKRHALGFPVNGQRTHTNAKTAKKLNR Mnele ------------------------------------------------------------------------------------------------- Monbr -------MYETRFKKIKGLGKFKIFNICQILGINEYSKLSEHYIDELNVLIEENLNDYESSQIIQINALRGRRIKMGYPSKGQRTRSNAITAKRINK Morel2 LHLLGVNLPDQKLVQFYGIGQKTALKVLATLSIHKIADLSEPQVNQLSMKIESDLRKQIRANIRSIGSYVGRRHAMGLPVRGQNTKNNAKTARRLNG Mucci2 LHLLGVNLPDRKLVSFYGIGEPTAIKLCQKLSIPKVIELSEVQVNELTMTIETDLKRQVREQVRNINNFIGRRHAMSLPVRGQRTRNNAKNAKKLNG Mydma ------------------------------------------------------------------------------------------------- Neucr2 VFILGVNFNEHKLVQFYGLGQQASARILAKYSIHKMGTLPPKIVTALTMTIENDARRLVLDNIRDMGTYRGRRHAMGLPVRGQQTRNQIANARKLNK Orpsp11 ------------------------------------------------------------------------------------------------- Pench1 ---------------FFGIGNNSSARLMSRFNIHRVGELANKQVLDLTMKIENDLRREVLNDIKETGTYRGRRHALGLPVRGQRTRTQVISACAVS- Phybl2 ------------------------------------------------------------------------------------------------- Picst3 VHVFGKSIKHNSLVRIFGIGYQTAERICAKVGIYRMNQLSEPQIMDLNLLVEGHLKQKINNDIRDIGSYSGFRHAQGLPVRGQGTRNNAATAGKLNK Plicr1 VYVLGVQLPDNKLARFYGIGDQTARRLCARFQIHKVRALSQNQITALAMKIELELRTEMQDNIRMIGSYVGKRHAMGLPVRGQNTQTNAKTARKLNR Polpo ------------------------------------------------------------------------------------------------- Pucgr2 MFILGVNLPEHKLVRFVGIGHYTANLICARLQIHTVGELSEHQIGRLSLLIESDLRREVRANIRAIGSYKGKRHALGFPVNGQRTHTNAKTARKLNK Punst1 ------------------------------------------------------------------------------------------------- Rhior3 LHLLGVNLPDRKLVSFYGIGEPTAMKLCKNLSIPKVAELSEVQVNELTMTIETDLKRQVREHVRNINNYIGKRHAMSLPVRGQRTRNNAKNAKKLNG Rhoto1 VNLLGKTLQDNKLVKFYGVGPVIAERIMARLQFHLVRELSERQLNALSLMIEEDLLRKYRADIYNIGTWRGLRHAMRLPVRGQKSHPNAKTAKRLNR Rozal11 ------------------------------------------------------------------------------------------------- Sacce1 VHILGKGFKGKEVIKFYGIGKTTAEKICSKLGFYRMHQLSEPQIMSIAMTIEGDARAIVKDNIRKIGSYSGMRHTLHLPVRGQHTRNNAKTARKLNK Salro ------------------------------------------------------------------------------------------------- Schco3 VHVLGIPLNDHHFARIYGVGRKTAHRICARLQIHRVKNLTPLQITQLALRIESELRREIRENIRMIGSYVGLRHAMHLPVRGQNTQSNAKTAKKLNQ Schpo1 VYILGVAVNDDKPVRFYGIGHAKAEEICAKLSFHRVRELTNVQLTTLSMTIEGDLRRQRNADIVNIRCYRGMRHVNGLPVNGQNTRTNAKTAKKLNK Sorma VFILGVNFNEQKLVQFYGLGQQASARILAKYSIHKMGTLPPKIVTALTMTIENDARRLVLDNIRDMGTYRGRRHAMGLPVRGQQTRNQIANARKLNK Sphar ------------------------------------------------------------------------------------------------- Spipu1 LYLLGVNLPDDKVVSIYGVGLKTGQTICHKLGIHRLKDLPEDKVTKLSMQIDAELKRETRNRIVQMGSYRGARHKAGLPVNGQRTHTNRSTAKRLNG Sporo1 VNLLGATLPDRKLVKFHGINHQTSSRIMARLQFHRVSDLTEPQMNALSLLLEEDLRRSRRADIRTVGTLKGRQHAMGLPVRGQRNKTNAKTAKKLNR Stehi1 ------------------------------------------------------------------------------------------------- Tapde11 ------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------- Treme1 MHLLGHHLPDHKLLRFYGISHSTSSRLLARLQIPRVSDLSESQITALSLKIETDLRRSVTADIRQVGSYRGKRHQQGLPVRGQNTRKNAMTARKLNK Trire2 VFILGVSFHEGQLVKFYALGPTTSARIMAKYSIHKVGSLSPKTVTSLTMSIESDARRQVQENIKDIGSYRGRRHAMGLPVRGQRTRTQTATANKLNR Umbra1 LHLLGVNLPDRKLVSFYGIGPTSSSKICDQLSIHKLAELSEAQINSLSMNIETDLKREVRDHVRSINTYAGRRHAMSLPVRGQRTRNNAKTAKKLNG Ustma22 MYLLGVHLADHKLVRFYGISYATANRLCARLSLHTVSSLTESQITQLSIKIEADLKRVLHANIRDVGSYRGRRHAAHLPVRGQRTSTNARTAKKLNR Walse1 VYLLGVNLPDNKLVKFYGIGLPTSERICAYLSIHKIGQLPEHQMTSLSFKIEADLRREVRSNIRQIGSYKGRRHGQGLPVRGQNTHSNARTARRVNR Zygro1 VHILGKAFKGKEVIRFYGIGEGTAEKVCSKLGFYRMHQLSESQIMNIAMTIEGDARAVVKENIKRIGSYQGMRHTLNLPVRGQHTRNNANTARKLNK [Cluster3210.fasta_al_trimmed; alignment length = 63] Allma1 FFRVTLVRSTIGLPAKTRQYAKSLHLTKLH-RPVLMPATASSAGNLLKLKELIKVENVDGFRV Ashgo11 FYKITLARSTIGLPDKVKGVVHSLGLGKRG-TTVYRKVSPGSAGSIAKIKELVKVEVTPGFTV Aspfu1 YFRVTLLRSAIGLPRRTTDVLKALGLKKRM-ATVFHPVSPSVAGQIMKVKELVEVQEVPGYYI Aurde31 HFRITLRRSAIALPERYQATLTTLGLHKRL-QTVYHPHSQSVAGKILKVKELVEVANVRGYSV Batde5 YFEITLRRGVIGLPKTTRDIVKCLGLHTRY-QVVWRLVGPRSAGQILKVKELVNVRLT----- Botbo1 HFRITLLRSAIGLPRTSSATLEALGIHRRM-ATVYHPHTPDIAGKILKVKELVKVENVRGYTL Botci1 --------------------------------------------------------------- Caeel --------------------------------------------------------------- Canalb1 YYRITQLRSSIGMPPKTRNTLLSLGLKRRY-QVTYVKVDQSSAHQLAMVKELVKVELSTGFEL Cangl YYKVTLVRSLIGTPEATRNIVKAIGLGKRG-SVVYRKVSPSMAGSLAKIKELISVDVTPGFTV Capow --------------------------------------------------------------- Catan2 FYKVTLRRSTIGLPETTRKYAKVMGLTRLH-KSVLLPVKPDTAGNILKIKELVEVENVPGYSV Cioin --------------------------------------------------------------- CocheC53 YFRITLMRSGIGMPAKTQGVLKALGLRKRM-TTVYHPVSQSVAGQIMRIKELVDVKEVPGYYV Coere1 LWKITLKRSTIGLHPQTRENARVLGLKRCG-HVVYRPVTNELAGIIIKVKEIIKLELVSGFEV Conco1 YFKVTLKRSTIGLHPRTRDAAKFMGLKKVG-RTVFLETSEKNVGHIFRVKELVKVELTKGYEI Conpu1 HYKITQTRSAIGLGEGKKETLVSLGLHRRM-QTVYHPHGPEVAGKVLKVKEIVQVENVRGYSV Copci HFKVTLKRSAISLGDKKKGTLLALGFHRRF-QTVYHRHTPEAAGMILSVKELVEVENVRGYQV Croqu1 HYRITLFRSAIGLPKPKRDTLASLGLKKRM-QTVYHRHSPDMAGLILNVKELLKVENVRGYRL CryneH991 HHLITLVRSPIGLTKASKQTLVALGLHRLR-QSVLQPFGEVTAGRILKVKELVQVANVRAIDH Crypa2 FFRITLHRSSIGMPQRTRDVLAALGLHKRG-RTVYHPVHPQFAGMIMKVKELVRVEEVKGYWV Debha1 FYKITQTRSTIGCHPRIRKNIEALGLKRRN-QIIYQRVSPSTAHRISVVKELVKIELVPGFEM Dekbr2 --------------------------------------------------------------- Dicdi --------------------------------------------------------------- Dmel --------------------------------------------------------------- Enthi --------------------------------------------------------------- Falba SFKITLRRSVIGTPKGTRDTIRALGLRHTN-HTVLRTATPSISGMIMKCKEMLEVEVVSTYSV Fomme1 YYKITLTRSAISLGTRKQATLASLGITRRM-QTVFHPHSPEFAGKILAVKELVHVENVKGFEV Fusgr1 FFRITLHRSAIGLPERTRGVLAALGLRRRM-QTVFHPVHPQFAGMILKVKELVRVQEVAGFYV Galma1 HFKITLRRSAISLGDKIKGTLKALGIHRRF-QTVYFPFSPEVAGKILRLKELVEVENVRGYKV Ganpr1 HYAVTLKRSLIGVPHTTAAIAKRLGLTKRE-RTVYLPISASAAGQILKLKELVSVRNLRGYTV Gloin1 FFKITLRRSTIGLPLKLRRVVRALGLRRLQ-QTVYHSQTAYIAGMILKVKEILQVINV----- Hisca1 YFRITLIRSAIGLPRRTTGVLMALGLKKRM-QTVFYPVTPDVAGQIMKVKELVSVREVPGYYV Klula1 FYRITLQRSVIGTPQKTRAVVKSLGLGKRG-SVAYQPATPSIAGAVAQIKELVSVELAPGFTV Lacbi2 HFKITMRRSAISLGEKIKGTVVSLGIHRRF-QTVYHRHSPETAGKILKLKELLEVENVRGYKV Lenti61 HYRITLRRSAISLPQNIKGTLEALGIHRRL-QTVYHRHTPDIAGKILTVKELVTVENVRGYSV Malgl1 HYRITLRRSAIGLPKHTGRVIEALGLRKRL-QSVYHRQSPDIAGMVLAVKELVHVENVRGFKI Mellp23 HYRVTLFRSAIGLPKPKRDTLASLGLKKRM-NTVYHRHSPDAAGLILNVKELLKVENVRGYRR Mnele --------------------------------------------------------------- Monbr --------------------------------------------------------------- Morel2 YYKVTQTRSLIGVPKSTIKVLKSLGLGRKIGRPVFQPHEPSAAGKILKVKELVKVENMKGYKV Mucci2 YYKITLKRSAIGLPQDIRAASKTLGLVRLH-QTSYKPVNASNAGLILKLKELVQVQVVRGYTV Mydma --------------------------------------------------------------- Neucr2 FFRITLHRSAIGLPKRTHGVLAALGLRRRN-QTVFHPVEPQFAGMLMKVKELVRVEEVAGFVV Orpsp11 --------------------------------------------------------------- Pench1 YFRITLIRSAIGLPRRSTDVLKALGLKKRM-ATVFHSVSPSVAGQIMKVKELVHVEECPGYYI Phybl2 --------------------------------------------------------------- Picst3 FYKITQTRSTIGMPPITRKNIEALGLKKRN-QIVYQSVSPSTAHRLARVKELVKVELVPGFNL Plicr1 HYKITLRRSAIALAAPVKATLVALGIHRRM-QTVYHAHSPAAAGMILRVKELVEVENVRGYAV Polpo --------------------------------------------------------------- Pucgr2 HYRVTLFRSPIGLPKRRHDSLVSLGLRRRM-DVSYHRHSPDAAGLILSVKELLKVENVRGYRL Punst1 HFRITLRRSAISLPDKIQDTVAALGLRRRH-QTVYHPHSPETAGKILKIKELVEVENVRGYTV Rhior3 YYKITLKRSVIGLPEETRAATKTLGLFRLH-QTTYKPVNAGTAGLILKLKELVKVELIRGYTV Rhoto1 HYLITLLRSPNHLGATVYSTTRVLGLTKRL-SSVIVPINPVNAGYILRIKELVGVRLVRGFKV Rozal11 --------------------------------------------------------------- Sacce1 FYKVTLSRSLIGVPHTTKSIVKSLGLGKRG-SIVYKKVNPAIAGSLAKVKELVKVEVTPGFIV Salro --------------------------------------------------------------- Schco3 HYKITSRRSAWGLGDRIKGTLVALGLHKRN-QTVYHAHAPDIAGKILAVKELVEVENVRGYKV Schpo1 FFRVRLERSAIGLSSKVRSVLHSLRLTKRH-SVVYCDVNPINAGRIFKVKELVSVSTVSGFTV Sorma FFRITLHRSAIGLPKRTNGVLAALGLRRRN-QTVFHPVEPQFAGMLMKVKELVKVEEVTGFVV Sphar --------------------------------------------------------------- Spipu1 YYEISLRRSLNGLPETTKEYARALGLVKRH-QVVWRKVGPRSAGQILRIRELVVVRLVAGYAK Sporo1 --------------------------------------------------------------- Stehi1 HFRITLKRSAIALPAHIKATLVSMGIHRRM-QTVFHPHSPEMAGKILTCKELLEVQNVRGFKV Tapde11 YLKVTLMRSAIGLPKKTNLVLASLGLRKRM-QSVFHTVSPQTAGMVLKVKELVHVEQVPGFIV Thetr --------------------------------------------------------------- Treme1 HHLITLTRSPIGLPPQARGTLEALGLYRRY-SSVLHPFGPTVAGQILRVKELVSVRNVEGSGV Trire2 FFRITLHRSAIGLPERTRGVLQALGLRRRM-QTVFHPAEPQFAGMIMKVKELVRVQEVRGFYV Umbra1 FFKISLKRSTIGLAPEFKAAAKTLGLHRSH-QTVYRPANSTNAGLILKLKELVKTKS------ Ustma22 HYRITLRRSGIGMPEKINRTLQGLGLKKRL-QSVYRPIGPAMAGAILAVKELVHVENVRGYKI Walse1 FYRVVLTRSAIGLPKESQRTLEALGLNKRM-SVVLHPHSADTAGQLLRVKELVKVDNISGFEN Zygro1 FYKVTLSRSLIGVPHTVRNVVKSLGLGKRG-STVYRRVTPQCAGSLAKVKELVNVEVTPGFTV [Cluster3212.fasta_al_trimmed; alignment length = 161] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ATKALNDVTG--YSSIEKLRKSIETKRKLMQLREAHSDAVAVRNQSQRQVNELLQRKHMWSPGDLESFTRLYKEDADNVRRQEEANASLKAMEAKEEELHRAILTRYHEEQIWSDKIRRTSTWGTFILMGLNILLFLVVQLLLEPWKRRRLTNSFEDKVKR Aspfu1 AGQRLNDLTG--YSAIEALKKDIEARQRVREAKNAYAAAINRRSASQREVNELLQRKHAWSAADLERFTHLYRNDHTNEVAEMETQEALSAAERESEELSKSILSRYHEEQVWSDKIRRMSTWGTWGLMGVNVLLFLVFQIAVEPWRRKRLVKGFEEKVIE Aurde31 MGLVLNRMSG--YDEIQGLKQTAQARQAARDAKAAYDKAAAARVASQREVNDLLQRKTSWSEADVSRFTALVRADHQLEQEEARAKDNVVRAEDGVEHLTQSILARYHEEQVWSDKIRRLSTYGQLGAMALNVLVFVTAIVWVEPWKRKRLGETFERRVEA Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 VGGKLNQVTG--YDEIEELKRHVMLREEAKDAKKAYENAVAQRSSLQREVNDLLQRKAIWNDADVSRYTVLVTQDHQHGLAEVRTKEAFALAEQEVEKLMRAILNRYHEEQMWSDKIRSASTYGSLAALGLNLVVFILAIVLVEPWKRKRLAQTFERKIVE Botci1 -------------------------------------------------------------------------MDHTNEQAVQEAATRLADAEREAEKLSSSILSRYHEEQIWSDKIRRMSTWGTWGLMGVNVLLFLVFQFGFEPWRRRRLVAGFEDKVRE Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ATRALNDVTG--YSAIEKLKKSIKAKEKVKQCKIAYGEAIQRRSHSQREVNELLTRKHNWSSNDLERFTELYRNDHENEIHEQEAEKKLDEAESKVDGLTQSILTRYHEEQIWSDKIRRSSTWGTWVLMGLNVLLFVVATFIVEPWKRSKLVSAFEDKVKQ Cangl ATKALNDVTG--YSSIQKLKNSIATRKARTDLKLQYTKAIESRTLSQKQLNELLQRKSSWSPSDLENFTKLYKDDAINQQTEKELKEKVRDIEKKEEQLYRAILTRYHEEQIWSDKIRRTSTWGTFILMGFNLVLFIIFQLLLEPWKRRRLTGSFEGKVRH Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 VTQKVNTYTGTDYSGVEALRREIARRSAIDAAKQALDTALAHQATSQKEVVALLERKHSWSNGDLERYMALIRSEHLNDQAVREAKDAVANAENALEDLEKRERAQYHEEQIWSDTIRRNSTWVTFGLMGVNIFLLLLSLAILEPWRRKRMVKEIKNALEA Coere1 AGKTLNVVTG--YDRVAQLKLKVSARQSLEKIKQQHAQTIKDRISSQREINSLLQRKHLWNEEDVARFTDLYRDEHQAESNEHKTATELKNAESLVDRLVSAIRERYHEEQIWSDKIRRASTYGTWAVLFMNIIALFLAQAIFEPRKRRKIVAGVDEKLAE Conco1 IGVNLNQVTG--YDQIEKLKNNIKINKELKRIKLEHEGNVNMRAGGQKEINNLLQRKHLWTDEDVTQFTQLYRNEHKNEQNEYTSKAQLKALESQVEQLIDSIRTRYHEEQLWSDKIRGASTYWTLALILVNLLAFILVHTWLEPRKRRRMVEQVSQEMDA Conpu1 LGAELNKVTG--YEQIEALKQTVAARRAARESKTAYDDAVVQRAVSQREVNDLLQRKSGWSDADVSRFTELVRADHALEQAEARAKAAVATSEDAVDKLMRAILARYHEEQVWSDKIRSASTYGSLAVLGVNMFVFVLAIVLVEPWKRRRLAQTFEGKVEE Copci LGQHLNRATG--YEEIEALKREVEARLAARKAKTAYEEAVLQRSKSQREVNDLLQRKSMWTDHDVSRFTTLVREDHLYEQEEARAKAAVNSTEDAVEKLMRLILARYHEEQVWSDKIRSASTYGQLAALGLNLIVFILAIILVEPWKRKRLAQTFERKVEE Croqu1 IPNKLSKLTG--YQEIEKLKKLVQSRKISQEAKLNYERASSKRSESVKEVNDLLARKASWSDDDLARFTNLVRKDHTNEQEEITAKNILKESESKVETLMQAILSRYHEEQIWSDKIRSLSTTFSLSITLINLLVFLSAIVFIEPYKREKVVGAVEERMVK CryneH991 LGLKVNEMTG--YHEVERLKYMVRLREHARTAKAAYDEAVAARSEAQRETNILLERKHSWTDADVSKFTSLVRSDHTSSHAVASTSIALKDAEVAVDKLMQVILQRYHEEQVWSDKIRSVSTWANVAGLAINFIIFVGAVLLVEPWKRKRLVEKLEERVTS Crypa2 ASQTLNDLTG--YSAIESIKAANTAQETLRGARAHYKAVNARRAATQREVTALLARKDTWSPLDLERFTTLYRQDHELEAAVGEAGTALTEAEAEEARLNSGILRRYHEEQIWSDRIRRQSTWGTWGLMGVNVLLFLVLQFVAEPWKRSRLMKGIAAEEKA Debha1 ATRALNDVTG--YSSIEQLKKSINEKDNVKKCKDLYSQAILRRSLLQREINELLTRKHNWSPDDLERFTTLYRNDHVNEQEELNTHNALNDAELKVDALTQLILTRYHEEQIWSDKIRRASTWGTWILMGINLFLFILATFLVEPWKRKRLVGSFEDKVKQ Dekbr2 ASRVVNDVTG--YSKVNALKEKIVLREEITRAKDDFSTAIEKRSESQREMNDLLERKSSWVPTDLKRFTELYMNEHELEREVKLKKIRLDELDQKNDELIKSIMDRYHEEQVWSDKIRQFSTWGTVLIMVCNLLLVFLVQLVFEPFKKYRLVRSFENKVRD Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LGGRMNEITG--YHEIETLKRLVEIREEAKASKAAYEEAVARRSNSQRETNELLQRKSTWTEADVMRFTQLVRADHLHSQDEARAKARVAEADAVTERLMRSILSRYHEEQVWSDKIRSASTYGSLAALGLNLLVFILAIVLVEPWKRKRLVQSFERRVIE Fusgr1 ASQTLNDITG--YTSIEVIKGQNEAHELVRTARQEYKTSNASRAATQREVTTLLARKDSWSPIDLERFTELYRADHTLEGKVASSQETLTEAEIEEQRLNAGILKRYHEEQIWSDRIRRASTWGTWGLMGMNFLLFVVLQFVAEPWKRKRLVRGVVAEEKA Galma1 LGSQLNRVTG--YEEIEALKRGVAARQAARAAKSAFEQAVVQRSNSQREVNDLLQRKSSWTDSDVGRFTTLVRQDHLYEQEEFRAKTSVDETEEAVERLLRKILARYHEEQVWSDKIRSASTYGSLAALGLNMLVFIMAIVIVEPWKRKRLAQTFERKIEE Ganpr1 SAALLNSVTG--YDTIIQARAQTSLRDSVKTAQKQYELTIESRAQCQRDINALLERKASWTPSDVASFTELY-----NTFLELDTNSNLKR------------------------KVQKNN---------------------FGPSQR------------- Gloin1 ----------------------------------------------------MLT----------------------------EAKEELHKYEKQVEKLSKSIMMRYHEEQVWSDKIRSASTYGTIALMTLNIILFICVQTIFEPRKRQKLAEKFEELLIK Hisca1 -----------------------------------------------------------------------------------------------------------------------MSTWGTWGLMGVN--------VAVEPWRRRRLVKGFEEKVME Klula1 ATRALNDVTG--YSSIQKLRNTIDTKKLVNEAKEKYETAIKARSGSQKEVNELLQRKNSWSPTDLDRFTQLYRDDALNSQTEEQSKVKLAELEAKEEELYRAILTRYHEEQIWSDKIRRTSTWGTFILMGVNILFFVIFQLLLEPWKRRRLVGSFEDKVKM Lacbi2 LGSQLNKVTG--YEAIEALKREVATRKAAKQAKVAYEEAVVQRSNSQREVNDLLSRKSTWTDGDVVRFTAIVRQDHLYEQEEARAKAGVNEMEDAVERLMRSILARYHEEQVWSDKIRSASTYGQLAALGLNLLVFVIAIVAVEPWKRRRLAQTFERKVEE Lenti61 LGKELNRATG--YEEIDQLKRKVNAREAARQAKEAHDTAVLQRAKSQREVNDLLQRKSHWTDEDVSRFTTLVREDHAREHDESRAKAAAAAAEDAVERLMRVILNRYHEEQVWSDKIRSASTYGQLAVLALNMAVFVLAIVLVEPWKRRRLAQTFERKVEE Malgl1 LGHRWNDFSG--YADINALKEQVTLQQEKDAAKEVYIQAVSDRSVSQRRVNDLLSRKSTWRDSDLMEYTSLLHSEHSHAKAEEQSQLEYERAEDNMQRLMRSVMRRYHEEHIWSDRVRSISTYVSVGLGALNVLVFILALFIVEPYKRRRLAQTLESRLLS Mellp23 LPNKLSKLTG--YGEIDELKLIVSFRQKALEMKKFYKKAVECRSESVREVNDLLARKASWSDGDLARFTTLVRTDHSNEQEELKAKNLLEEAEAKVDQLMQAILSRYHEEQVWSDKIRSLSTTFSLSITLINVLVFLAAIVLVEPYKRAKVVEGVENRIMA Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LSEHLNNFTG--YTSINELKHKVESRIKLAQAKQAYEDAIGTRSDTQKAINDLLQRKHLWSPNDVIRFTDLYRSEHANEQAELKSKQEYKQAEANVEELMTIIMERYHEEQVWSDKIRAASTYGTWGLIGMNIMAFLIVQGFVEPRRRRKQVERYEELV-- Mucci2 ASRALNELTG--YDQIDAVKQKVTTRDQVQAAKRAYEDAIETRSTTQRGINELLQRKHLWTGDDVTKFTELYRLEHAHSQAETVAKEKYQACEKQMDRLARSIMERYHEEQLWSDKIRSVSTYGTWALMVVNLLLFVAVQTVFEPRKRKRLTDRFEELLVA Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ATQTLNDLTG--YSAIEQIKRKNQAQSRLRDARHNYKSLTMHRASTQREVTTLLARKDTWNPLDLERFTSLYRLDHELEAQVAQAAQELTEAETEESRLNAGILKRYHEEQIWSDRIRRQSTWGTWGLMGVNVLLFLVLQFVAEPWRRKRLMKGIAENEKG Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 AGQRLNDLTG--YSSIEALKKDITARTKVKEAKEEYSAAINRRSTSQREVNELLQRKHAWSSTDLERFTLLYRNDHTNEVAETETSQALSAAEREAEELSKSILSRYHEEQVWSDKIRRMSTWGTWGLMGVNVLLFLVFQILVEPWRRKRLVKGFEDKVVE Phybl2 ASRALNELTG--YNHIELVKHKVATRDSVQLAKRSYETAIETRSSTQREINELLQRKHLWTGDDVTRFTELYRLEHEHSRAEINTKELYRQAEKQMDRLARSIMERYHEEQLWSDKIRSVSTYGTWALMVVNLLLFVAVQTVFEPRKRKRLTDQFEELLVA Picst3 ATRALNDVTG--YTAIAKLKKSIEAKEEAKSNRATYSEAILRRSNLQREVNELLTRKHNWTPEDLERFTELYRNDHLNEQLEQEAELKVEEAEQKADSLTQLILTRYHEEQIWSDKIRRASTWGTWILMGINIMLFVVATLIVEPWKRRRLVASFEDKVKQ Plicr1 LGSELNRMTG--YEAIEALKRQVATRQAAQEAKTAYDKAVAERSNSQREVNDLLQRKSQWTDSDVGRFTTLVRQDHLYEQAEAQAKANVTHSEESVERLMRAILERYHEEQIWSDKIRSASTYGSLMVLGLNMVVFVLAVVVVEPWKRKKLAATFERKVEE Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 FPSKLSQLTG--YGDIDKLKSLVASREDAVQAKIKYNLAAQRRAESIKEVNDLLARKASWSDQDLARFTTLVRTDHSNEQAESEAKKGLEESEAKVDHMMQAILTRYHEEQVWSDKIRALSTTFSLSITLINVLVFLAAIVLVEPYKRSKVVSEVEDRIVK Punst1 LGGQLNHVTG--YNEIDDLKRRVETRKAAREAKAAYDDAVTRRAQSQKDVNDLLQRKSSWKDDDVARFTTLVRADHLHEQEEMRAKENLDRADMAVERLMRAILDRYHEEQVWSDKIRSASTYGSLAALGLNLFVFITAIIIVEPWKRRRLAQTFEKKVEE Rhior3 ASRALNELTG--YNHIETVKHKVATREDVQIAKREYERAIETRSNTQRNINELLQRKHLWTADDVTHFTELYRLEHAHTQAEAMAKERYQSCEKQMDRLARSIMERYHEEQLWSDKIRSASTYGTWALMGLNLILFVAVQTVFEPRKRKRLTDRFEELLVA Rhoto1 AGAKINQATG--YEEIERLRNGVDAREQAILLKRDYTERVKLRADSQREVNDLLQRKPTWNGPDVLRFTELVQQEHENERAEAKAKAEMEAGEEAVERLMQAILERYHEEQVWSDKIRSMSTYGSLAITGLNVLLFIVTLLLIEPWRRRRLVQNVEERLRT Rozal11 YAREFDKLTG--YDLCSQLRIRVDMKQQLSQIKERYENEVERRSDNQKELQELLQRKGSWSDTEIIRFAELHREEMKCDTNVKEAKKNLKYMEQVVDELMNVMRERYHEEQLWSDKIRRASTYGTLTVMIAQALLFLISILIIEPRRRKEIVESFNKQLAE Sacce1 ATRALNDVTG--YSGIQKLKSSIATKKEHKLFKAQYANAIDERAQSQREVNELLQRQSAWSSSDLERFTQLYKNDALNARQEQELKNKVKEIESKEEQLYRAILTRYHEEQIWSDKIRRTSTWGTFILMGMNIFLFIVLQLLLEPWKRKRLVGSFEDKVKS Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LGAELNRVTG--YEEIDALKKDVEARKAARDAKLAYERAVLQRSNSQREVNDLLQRKSTWTDTDVSRFTTLVREDHLFEQAELRAKAQADAAEEAVERLMQAILARYHEEQVWSDKIRSASTYGQLAALALNLLVFILATIAVEPWKRRRLAATFERKVEE Schpo1 ASQRLNELTG--YSSIEALKNAVDFRLSAAEARKRYIEAVEKRSSSQREVNELLQRRSSWSTIDLERFTKLYRDDYSNKEEEIKAQEDVDVAERRVEELVRSILSRYHEEQVWSDKIRQASTWGTWGLMGINVVLFVVVQLILEPRKRKRLVREAVDHIDK Sorma ATQTLNDLTG--YSAIEQIKRQNAAQTRLRDARHNYKSLTMHRASTQREVTTLLARKDTWNPLDLERFTSLYRLDHELEAQVAQAAQELTEAETEESKLNAGILKRYHEEQIWSDRIRRSSTWGTWGLMGVNVLLFLVLQFVAEPWRRKRLIKGIAENEKG Sphar TSERINALTG--YEGIMRLKAGVSARVAYKEAQAYLADILKQRRTAQQEINSLLQKQQHWGSEDVVKFGELHRLEHQLKRSEEAAEKALERAEGNVETYTLAIRERYHEEQLWSDKIRSISTYGTLIVMAFNFFLVFLSLVAFEPRKRRRIIAGVNERLED Spipu1 LSDLLNTLTG--YSVVQECKNRVVARERSDMAKRAYEQTIEERRKCQRELNSLLQRKDTWLDSDITRFTELYRKDLNLEQSESQAKQEYKDAVEGFEKYLNEIRERYIEEQLYSDKIRRASTWWTWGLISLHFAIFVVVQLFVEPRKRRILKEELGNLITE Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 LGGRINKVTG--YDEIDALKKGVAARTAAREAKLSYEAAVEQRSSSQREVNDLLQRKSSWKTPELTRFMELIQEEHIREQEEARSKNAVRQTEEEVEKLLRLILARYHEEQVWSDKIRSVSTYGSMAVLGVNVFVFLLAIILVEPWKRKRLAQTFEKKVEE Tapde11 AGQRLNDLTG--YSGIERLKNQIRTIERVREAKKAYEEAIRTRSESQREVNELLQRKSSWSSSDLERFTTLFRNDHSNSRNEEQSQQDLTNAEIEVDQLGNMILARYHEEQIWSDKIRRASTWGTWGLMGFNIFLFVLVQLGLEPWKRKRLVGSFEEKVRH Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 ASQKLNEITG--YTSIDAIKMENEAQARVRAARQAYKTSNNKRASTQREVTTLLARKDTWTPADLERFTELYRTDHILEGEVITAQENLTEAEADEQKLSAGILKRYHEEQIWSDRIRRASTWGTWGLMGMNFILFVVLQFVAEPWKRKRLVKGVVAEEKR Umbra1 ASTALNELTG--YTHIEDVKKKVSCRTELRNCKAAYEDAVDVRSSTQREINELLQRKHTWTGEDVTRFTELYRLEHLHSQQEMTAKENYRQSEKHMDRLTRAIMERYHEEQLWSDKIRSVSTYGTWALMVVNLILFVAVQTVFEPYKRKRLTDRFEDLLVQ Ustma22 LSSQYNMHTG--YTAIEELKHRIAARTLASTAKKTYLMAVQERSASQRETNDLLSRKNSWSETDLSRYTELLRKEHALSRHESEAEKELERSEAEVQALMKAVLVRYHEEQVWSDRMRGMSTYASLVVAGLNAFLFILAILLVEPYKRKKLAETFEKRLVA Walse1 ----LNRLTG--YERIENLKAVVQSRTMLIDSKREYTKYTELRRQSQKQVNDLLSNKSSWGDTELNKFTQLVKSDHSIEKLEKEFMQKVEEYEKLVDRLLKSILERYHEEQIWSDKIRSMSSNYTLIALSVNVLVFLMAIVFIEPYKRNRMLRELE----- Zygro1 ATRALNDVTG--YSSIQKLRKSIETRSELRELKEDYAMAIEERTRSQRELNELLQRKNIWTPEELERFTLLYKNDAMNLKKEQQLKTKVNAMEVKQEKLYRAILTRYHEEQIWSDKIRRTSTWGTFLLMTVNIILFLVFQLLLEPWKRRRLTSSFEVKVKQ [Cluster3216.fasta_al_trimmed; alignment length = 95] Allma1 ----------------------------------------------------------------------------------------------- Ashgo11 ----------------------------------------------------------------------------------------------- Aspfu1 SLDAAERKARLAKLAALKLSGRNFDATRGPKTLEAQAAIAKATKKDEEKDQP--IDL-FKLQPKKPNWDLKRDLDEKMKILNVRTENAQRMENAQ Aurde31 SLVEAARKARLLALRKRKVKHRNFDPTRTLRTVERAVDLAEKIEDAERRNQE--LDI-FSIAPKRPNWDLKREMERKLAKLERRTQEAQRLAAQQ Batde5 GLSEANRKERLAALRKQVLRFRNYQPTDALKTVEGQAEIKHDAEAEEARNKE--LDL-TNLAPKKPNWDLKRDLNKKLEKLDRKTKKAQRL---- Botbo1 SLADASRKQRLLALRQRKFKPRNYDPTRTLKTVEKNVALAEMIEDEEKRAQE--LDL-LNIVPKRANWDLKRNMERKLAKLERKTQESQRLAAQK Botci1 TLGAAERKARLAKLKSLKLSGRNYDPTKGPKTLEQQAAVEEEIEEEEQDDKG--IDL-FKLQPKKPNWDLKRDLEKKMEVLNVRTENAERIESAQ Caeel SLEAAARKRRLLAMKSKIREFRNHKPDAVGTIVQREITHLKDV---EKAIDS--VDL-AMLAPKKIDWDLKRDIESKLQKLERRTQKAQRLAEGK Canalb1 ----------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------- Capow SLQD-KRRARLRAMREGALRFRNYTPDAKLA---------EPEAKADARIHD--IDL-VNLAPRKQNWDLKRDVTKKLEKLERRTNRADRLTAQ- Catan2 ----------------------------------------------------------------------------------------------- Cioin NLEEAKRKERLKAMREQRLKLRNYNPGDDLKQITNQLEQAAEPQEE--------VDI-LKLAPRKPDWDLKRDIQSKLDRLERKTQRAERLKQST CocheC53 TLSAADRKSRLAQLKSLKLSGRNYDPTRNVKTLEYKAELALETEAEKAEDKG--LDL-FKLQPKKPNWDLKRDLDQKMKPLHVQTDNAERVE-AQ Coere1 SLEAEKRKARLQALSKSLLKLQNYKATKSSCTIENSVALVEAADDIGE------LDI-SAIAPKRANWDLKRDLQKRLDHLKPKNDAAKRIQ--- Conco1 -MASNDRLNRLKNLINRKLKFRNYETSNEITTVEDQVNIQKPIAHQSKLQSE--LDV-IALAPTQLEWDLKSDLDKRMKKLNKLTQKKLRLNPPA Conpu1 SLQEAARKARLIALRQRRILNRNYDPTRTLKTIEKNVEMAEMIEDEQRREQE--LDI-FNIAPKRPNWDLKREMDKKLAKLERRTQEAQRLAAQK Copci SLQEAARKARLLALRRRKIKTRNFDPSRTLKTVEKKVKLAEQIEDEARRQQE--LDI-FNIAPKRPNWDLKRDMEKKLAKLERRTQEAQRLAAQK Croqu1 SLADQVRKEKLKALAKRKFRFRNYDPIQGPRTVEEAVKVMERVEDELRRAGE--LDL-NKIQPKKPNWDLKRDLMKKMAKLEPITQAAKRPSSK- CryneH991 NLAATARKERLIALRKRKLKQRNYDPTRGFRTVEKAVELAEQIEDEEKRNEE--LDL-FNIQPKRANWDLKRDMNNRMGKLERKTNEAQRLQAMR Crypa2 KLSAADRKARLAKLKSLKLSGRNYDATKGPKTLEDQAALEAELAEEAEDDKG--IDL-FKLQPKKPNWDLKRELNKKLEVLNVRTDNAERLQSKQ Debha1 ----------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------- Dicdi NIDNKQTEKEIETEKETKLKFRNYIPDQTFLRIEKAVVIAQELEENQ--------DIQISFVPKKVNWDLKRDCSKKLLKLEKQTEKAQKLGKEE Dmel KLTQEKRKERLQKLREQV-VFRSYKPNETTDAVEDQL-LLQQPIDE--------IDI-TNLAPRKPDWDLKRDASKKLERLERRTQKAERLKLNQ Enthi ----------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------- Fomme1 ----------------------------------------------------------------------------------------------- Fusgr1 SLSAADRKARLAKLKNLKLSGRNYDPTRGPKTLEEQAAVEAEIAEEAQDDKG--VDL-FKLQPKKPNWDLKRELDTKMEVLNVRTDNADRITGAQ Galma1 SLAEAARKARLIALRKRKIKNRNFDPSRTLRTVENQVKLAEQIDDEKRRAQE--LDV-FNIAPKRPNWDLKREMDKKLSKLERRTQEAQRLAAQK Ganpr1 NLLEDKRKDRLLAFRAEKAYERDHNPKTFVITLEEEVAFAKEADQEDQRKKE--VDI-FNLAPRKANWDLKRDLQKKRAKLERKTQSSNRLSTAG Gloin1 -MEEAQRKERLEALRKRKLKFRNYTPNEDIKTLENTVEIAKQVEEEKKREEE---DL-FNLAPKKPNWDLKRDVEKKLAKLEKKTQSSIRLQ--- Hisca1 TLDAADRKARLAKLASLKLSGRNYDPARGPKTLEERAQIAISTKEDEEADKP--IDL-FKLQPKKPNWDLKRDLDEKMKIVNVRTQNADRIQNAQ Klula1 ----------------------------------------------------------------------------------------------- Lacbi2 SLAEAARKARLQALKKRKIKSRNFDPSRTIRTVEKDVALAEQIDDERRRAQE--LDV-FNIAPKRPNWDLKRELEKKLSKLERKTQEAQRLAAQK Lenti61 SLADAARKARLLALRKRRIKHRSFDPTRTLKTVEHRVELAEKIEDAERRAQD--LDL-FNIAPKRPNWDLKRELDKKLAKLERKTQESQRLAAQK Malgl1 GIESAERKARIAALRALRQHFRTSRPPAGMLTLEQEVDMQEQVEDTRKQAEE--LDL-TNIAPRRANWDLRRDLDERLARLEPKTQAAQRIRASR Mellp23 ------------------FRFRNYDPIQGPRTVEERVKVMEQVEDEIRRSGE--LDL-TKIQPKKPNWDLKRDLLKKMSKLEPVTQAA------- Mnele ----------------------------------------------------------------------------------------------- Monbr -MED-ERRARLKAMRAN-LKFRNYRP-----QIELANDVENAVKANDDVLQQ--VDV-LSLAPRKVDWDLKRDLEPKMAKLEKRTKRAERLQDDT Morel2 -MDEAKRKERLEQLKKRKMSFRNYTPNETLKTVEKKMEVVEKVEEDEKRAKD--VDI-FTLAPKKPNWDLKRDIEPQLLKLEKKTRAA------- Mucci2 -MDQEKRKERLAAIRKRKLKFRSYTPDEKLQTLETETKFTKEAQAAEKQKEE--VDL-FNLAPKKPNWDLKRDVEKKLERLDRRTQRAQRL---- Mydma ------------------IKFRNYTPDPLLK-------VLENIGKLQTAVED--VDL-TTLAPRKPDWDLKRDVTNRMDKLEKRTQKAERLNAE- Neucr2 TLAAADRKARLAKLKSLKLSGRNFDFTRGPKTLEEQAAIEEEAAQAAEENKG--IDL-FKLQPKKPNWDLKRELNQKMEVLNVRTDNAERLAAKK Orpsp11 ----------------------------------------------------------------------------------------------- Pench1 NLDAADRKARLAKLAALKLSGRNYDPTRGPKTLEAQAAIARATKEDTGADEP--LDL-FKLQPKKPNWDLKRDLDEKLKILNVRTENAQRVEDAK Phybl2 -MEEEKRKERLEALRKRKLSFRSYTPDEKLKTVETETKITKEVKAA---------DL-FNLAPKKANWDLKRDVEKKLEKLDRRTQRAQRL---- Picst3 ----------------------------------------------------------------------------------------------- Plicr1 SLAEAARKARLIALRKRKIKNRNFDPSRTLRTVEKDVAMAEKIEDEERRAQE--LDV-FNIAPKRPNWDLKRELDKKLAKLERKTQEAQRLSAQK Polpo TVDDNVQQADVEMTNNNELKFRNYVPDISLTVVE----LLEKLAESQQSEES--I----SFLPKKANWDLKRDVEKKLSKLDKKTNRAQKLDAEE Pucgr2 AICSQSRKEKLNELRKRKFKFRNYDPIQGPKTVEETVKLMEKVNDEAIRSSE--LDL-TKIQPKKPNWDLKRDLTKKLSKLEPITQAARRMQAE- Punst1 SLQEENRKARLEALRARKVSHRNYDPTRTLRTVEKNVQLAEKIEDEERRAQD--LDL-FNIAPKRANWDLKREMEKKLAKLERKTQEAQRLAAQK Rhior3 -MDQEKRKERLAAIRKRKLRFRSYTPDETLKTIESETKFTKEAEHAEKEKEE--VDL-FNLAPKKPNWDLKRDVEKKLQRLDKRTQKAMRL---- Rhoto1 SLQEAARKAKLAALKKRKFKFRNYDPTGTARTVEKQVELTDAAQDEAQRAQE--LDL-TNIQPKKPNWDLKRDLERKLAKLKPKTELAKRLQAQK Rozal11 ----------------------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------------------- Salro ------------------LKFRNYRPGDALAAMEEAEDLERDVMDEEDPMKD--IDV-LSIAPRKVDWDLKRNIAPRLEKLEKRTNRAERLRDAK Schco3 SLAEAARKARLQALRRRKLKHRNFDPSRQAKTVEKSVALAERIEDEERRAQE--LDV-FNIAPKRANWDLKRDMEKKLARLERRTQEAQRLAAQK Schpo1 SLDEVSRKQRLAELRKIKIEHRNYDPVQAPKSVEALSKIEEKTEQSSVPVEE--LDL-VTLRPKKPTWDLERDLKERMRSLETQNQNAERAHSTE Sorma TLAAADRKARLAKLKSLK-------------TLEEQAAIEEEAAQAAQENKG--IDL-FKLQPKKPNWDLKRELNQKMEVLNVRTDNAERLAAKK Sphar TLEDEKRKARLAALRAQVIRLRNYQPSEVPVLAEEEKQINAEV------------DV-SKLAPQKVTWDLQRDLTKRMDKLDRRTDRAKRLKDAT Spipu1 DLQEEKRKERLAALKALRGDQSEESPAEDIQTVEEHAEVARIAETEAKRKRE--VEL-LDLAPKKPNWDLKRDLEQRMDRLQRKTQGCARLREEG Sporo1 SLQAAARKEKLAALKKRKFKFRNFDPTGLARTVEKQTDLADQVRDEQARAQE--LDL-TNIQPKKANWDLKRDLERKLSKLKPKTELAKRLQAQK Stehi1 SLAEVARKARLAALRRKRLNTRNFDPTRTLRTIEKNVELAERIEDEERRAQD--LDL-FNIAPKRPNWDLKRDMEKKLAKLERQTQQAQRLASQN Tapde11 SLENQKRKERLALLSSNKMKFRNYDPTNAPKTVETRAKLVE--EDLTAREASDPLDL-FTLQTRKPNWDLKRDLNRKLERLKSKQDTVERIHASK Thetr ----------------------------------------------------------------------------------------------- Treme1 DLAATARKERLIALRKRKFKQRNFDPTRQVRTVEKAVELAEEIEDELKRAEE--LDL-FNIQPKRVNWDLKRDLNNRMMKLERKTNEASRLQSMK Trire2 SLSAAERKARLAKLKTLKLSGRNYDPTRGPKTLEEQAAVEAEVAEEARDDKG--LDL-FKLQPKKPNWDLKRNLEKKLEVLNVRTDNAERVQSAQ Umbra1 -MEAEKRKQRLQALRKRKLSFRNYTPDEELQTVEQETRITKEAEAERMHKEE--IDL-FSLAPKRANWDLKRDVEKKLESLDKRTQRAERL---- Ustma22 SLEEFARKHKLSLLRSLRRHFRNYDPTGQLKTVEKHVDLERQTQDERQRNEQ--LDL-TNIAPKRANWDLKRDLERRLKKLEPADSQAQRIQSQQ Walse1 VLEIADRKHRLAALKNRTLKFRNYDPSREPKTVEYAVKLAESIKDEELRNEE--LDV-FNIAPKRPNWDLKRELSKKMHLLNKADQLAQRLSKPD Zygro1 ----------------------------------------------------------------------------------------------- [Cluster3226.fasta_al_trimmed; alignment length = 133] Allma1 LHEWCRLEYAHMLIFTNMQDRICLLDMEGPKDLEPADAFDYMLFGGILGDDRTSILRKLGFPSRRLGPVHMTTDTAVIATHLILE-KKQIVFSDLPTVHFSDSVELPYRYITPKLPPGMYELLKRDNECDVFD Ashgo11 FSEWVTLEYAQILILSSLPGRVCLLDPRASGDLAPSDKFDYFVFGGILGDDRTSELKESYLVGKRLGDKQMTTDTAVRTTQLIVE-KQKISFIDYPEFRFNEATEMPFRYVRPILPSGMLELIKKDSEQS-LD Aspfu1 LGPWSALEYGCIFLLSSVPSKVCLLDPAAQVELSPEDGFDVFLFGGIL--DRTSELRKKGYVGRRLGPKQMTTDTAVRVTRIVAQ-GKKIEYVDDPEIIVNERIEMPFRYVQPIMPAGMVDLIKKDADKA-VD Aurde31 VPEWVELEYRHMVLFTNLSERVCLLDPKAEKELAPEDGFEWFLFGGILGDDRTAELRKLGFPNRHLGSVQMTTDTALGVTKLVVR-DKEIPHVDFPTIVFNESVEMPFRYIQPVLPVGMREHLQKDLDRG-FD Batde5 IEGWPELEYRNMLWLSHVSSRVILADPAAKTPLCPADAYDYILFGGILGDDRTKELRVMGFATRHLGKEQMTTDTAVLVSQLVLE-KQKIDYVDRPDIKLGEIVEMPFKYIEPKLPLGMIEHLKQGNDIS-LN Botbo1 -----------MVYFAHLSERVCLLDPRAERELSPEDGFDWFLFGGILGDDRTSELRVLGFPNRHLGPVQMTTDTALGVTKRVVV-DQSIPYTDHPTIQFNESVEMPFRYIEPCMPPGMRALLHEDLNKS-FE Botci1 LGPWSELEYITIFCLSSIPSRVCLLDPAATKELSPEDGFDVFLFGGILGDDRTSELRKKGFEGRRLGPIQLTTDTAVRCTRMVTQ-DKKIPYVDYPELRVNESTEMPFRYVKPIMPEGMVELIKKDTEKG-FG Caeel ------------------------------------------------------------------------------------------------------------------------------------- Canalb1 FSEWVILEYTQILILTSLPSKVCLLDPAAETDLTPQDKFDYFVFGGILGSDRTGLLREKYFSGRRLGSLQMTTDTAIRTTQRIIE-NGDIKFLDYPEIKYNESTEMPFRYVNPILPEGMLELIKNDAEQS-ID Cangl FSEWVTLEYAQILLLTSLPGRVCLLDPRAELDLQPEDSFDYFVFGGILGDDRTKELNIAYLVGRRLGDKQMTTDTAIRTTQLIIK-DQDIKFIDYPEFRFSEATEMPFRYVNPILPEGMLQLIKKDSQQS-LD Capow ------------------------------------------------------------------------------------------------------------------------------------- Catan2 LHEWCRLEYSHMLIFTNMHDRICLLDMEATQELSPEDAFDYMLFGGILGDDRTSILRKLGFPSRRLGPIQMTTDTAVITTHLILE-KKTIEFCDLPEIKFSESVELPYRYIEPMMAPGMFEKLKRDNEEDLFN Cioin ------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LEEWSSLEYSAIFLLSSVPDKVCLLDPAASKDLSPEDGFDIFLFGGILGDDRTSELRKKGYQGRRLGPVQMTTDTAVRVTRICVQ-DKQIPYIDHPDLKINESTQMPFRYVQPIMPEGMRDLIVKDSAKS-LN Coere1 ------------------------------------------------------------------------------------------------------------------------------------- Conco1 IFPWCKLEYSHMLIFTNLNEKICLLDQEASSVMQTTDDYEYLLFGGILGDDRTSELRKFNFPTRHLGAAQMTTDGAVLVSKIIVE-DKDIEFVDHPEIKLGDSTIMPFRYV-PRMAPGMIDLLKEDQ----FE Conpu1 LPPWVELEYSQMVLFTHLSESVCLLDPKAEKELSPEDAFGYFLFGGILGDDRTSELRALGFPSRHLGSVQMTTDTALGVTKKVVH-DKQIPYVDFPTIRFNESVEMPFRYIQPILPPGMRELLHEDLNKS-FE Copci IPTWVELEYAHMVHFTSLSEKVCLLDPKAEKELSPEDGFEWFLFGGILGDDRTGELRVLGFPNRHLGPVQMTTDTALGVTKLVVD-DKKIPYVDFPTIRFNESVEMPFRYIEPKLPPGMRELLHEDLNKS-FD Croqu1 MPEWVVLEYQHIAVFANLTSEVCLLDPRAEQAIGPSDAFRWFLFGGILGDDRTAQLRKFGFPSRHLGPVQMTTDTAVAVTKRVIE-DGKLLWTDRPTITFGESVEMPFRYLEPIMPKGMKELIRKDMDRA-FE CryneH991 LPEWVTLEYSHMVHFTSLSARVCLLDPRAEKVIAPEDAFDVFLYGGILGDDRTGELRKLGFEGRHLGEKQMTTDTAVGVTKKVIE-DQEIPFVDFPTIKFNESIEMPFRYVEPILPPGMKAHLKADLDRT-ID Crypa2 LGPWSELEYIAIFTLSSVSNTVCLLDPAAEKDLSPEDAFETFLFGGILGDDRTSELRKKGFPGRRLGPVQMTTDTAVRVTRIVIQ-QQEIQYLDHPDLKINESTQMPFRYVQPIMPKGMRELIAKDADKA-ID Debha1 FSEWVILEYSQILILTSLPSKICLLDPAAEVELVPEDNFDYFVFGGILGSDRTGILRKKYLAGRRLGSLQMTTDTAIRTTQKIVK-DQSIEFLDYPEIRYNEATEMPFRYIAPILPEGMLELIKHDAEQS-ID Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------- Falba LSTWSLVEYMHTLMITNLSEEICLFDLEAKETVSPADGFKYFVIGGILGDARTSKLRELSCEIRLLGDYQMSSDTATIVSYLITACGKDLPLIDNPTFQLGEGVEMPFRYLRPLVPKGFIRNLRRDEDKGVIN Fomme1 LPEWVELEYLHMIHFSHLSDQVCLLDPKAENELSPQDGFQWFLFGGILGDDRTAELRKLGFPTRHLGNVQMTTDTALGVTKKVVH-DRDIPYVDFPTIRFNESVEMPFRYIEPLLPPGMRDLLHKDLDKG-FE Fusgr1 LGPWSELEYLAIFILSSLPSKVCLLDPSAAKDLSPEDGFDAFLFGGIL--DRTSELRKKGFEGRRLGPKQMTTDTAVRVTRIVVQ-DKQVPYLDFPELKFNESTEMPFRYVKPIMPKGMVELIQKDSDKA-VN Galma1 IPPWVELEYAHMVQFTSLSEKVCLLDPKAEKELSPEDGFEWFLFGGILGDDRTSELRVRGFPTRHLGPVQMTTDTALGVTKLVVH-DREIPYIDHPTIIFNESVEMPFRYIEPRLPPGMKKLLHEDLNKT-FD Ganpr1 LYEWLRLEYAHLVLITNLPSRVCFLDEVGTTELRPDDAFDWFVFGGILGDDRGKSVREAQFEVRHLGPHQFPVDHAVLCARLILE-KGQISFAPGP---------------PTIFPVGSG------------- Gloin1 LHEWCLLEYYHILYFTNLSDKICLLDPASNQVLEPTDGFEYFLFGGILGDDRTSELRRLGFTTRNLGAMQMTTDTAVHVTKRIVD-DRQIPYIDFPEIKISESVIMPFRYIVPLLPSGMIDLLKKDGDMA-FE Hisca1 ----------------------------------------------------------------------MTTDTAVRS-------DQ-------------QRWAMPFRYVKPIMPEGMIELIKSDSDKG-LD Klula1 FSEWVTLEYAQILILSSLPQRVCLLDPRAKTDLIPSDAYDYFVFGGILGDDRTRELMEQYLVGKRLGDKQMTTDTAIRTTQIIIE-KQDVKFIDYPEFRFNEATEMPFRYVQPILPEGMLQLIKKDSEQS-LD Lacbi2 IPPWVELEYAHMVQFTHLSNNVCLLDPKAEKELSPEDGFEWFLFGGILGDDRTGELRILGFPTRHLGSVQMTTDTALGVTKLVVQ-DKDIPYIDYPTIKFNESVEMPFRYIEPRLPPGMKKLLHEDLNKT-FD Lenti61 IPRWVELEYMHMVHFTHLSDKVCLLDPKAEKELAPEDGFEWFLFGGILGDDRTSELRVLGFPGRHLGPVQMTTDTALGVTKIVVQ-DKKIPFVDFPTIVFNESVEMPFRYIEPILPPGMREHLKSDLDKS-FD Malgl1 FPPWALLEYRHMVHFTALSERICLLDPKAPLPLAPSSAFTHFLFGGILGDDRTSSLRNMGFPGRHLGSVQMSTDTAVGVTKRVVE-DGSLVFVDSPTIEFGESVRITSRCL---------------------- Mellp23 LPEWVVLEYHHIVIFANLSSEVCLLDPRAETVLEPADAFRWFLFGGILGDDRTAQLRKFGFPSRHLGPIQMTTDTAVAVSKRIVE-DGNLPWTDRPTLNFGESVEMPFRYLSPIMPQGMKELIHKDMDRA-FE Mnele ------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------- Morel2 MHDWCTLEYEHMIYFTALTEKVCLLDPASPYPLAPEDAYDFFLFGGILGDDRTGELRKLGFATRHLGPVQMTTDTAVNVSRRVVE-GKKIQFIDHPEIKLRETVTMPFRYIEPLLPPGMLELLKKDNDTA-LD Mucci2 MHEWCALEYKHMLYFTSLTEEICLLDPAGTSELAPEDGFKYFLFGGILGDDRTGELRKLGFAGRRLGPVQMTTDTAVNVTRKVVE-DKEVPYIDYPEIFFSESVTMPFRYIKPLMPPGMLELLKKDNEMT-LD Mydma ------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LGPWSELEYLAIFHLTSLPSRVCLLDPAAKKDLSPEDGFDVFLFGGILGDDRTSELRKKGFEGRRLGPVQMTTDTAVRVTRLVVE-GKKIPYVDHPELKFSESTQMPFRYVKPIMPAGMVELIKKDSDKA-ID Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------- Phybl2 VHEWCVLEYKHMLYFSGLTSEICLLDPAGTSELAPEDGFKYFLFGGILGDDRTKELRKLGFAGRRLGPVQMTTDTAVNVTKRVVE-DRKIPYIDYPELKFSESVTMPFRYIKPLMPPGMLELIKKDNDES-LE Picst3 FSEWVILEYTQILILTSLPSRVCLLDPAATQNLTPSDAFDYFVFGGILGSDRTGILREKYFAGRRLGELQMTTDTAIRTTQKIVE-NQDIKFLDYPEIRYNESTEMPFRYIEPILPVGMLELIKHDAEQS-ID Plicr1 IPPWVELEYAHMVHFTHLSHKVCLLDPKATEALSPEDGFEWFLFGGILGDDRTAELRVLGFPTRHLGSVQMTTDTALGVTKKVVD-DKQIPYIDYPTITFNESVEMPFRYIDPILPPGMRELLHEDLNKS-FD Polpo ------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LPEWVLLEYFHMVFFSHLSEEVCLLDPKAEQELKPEDGFRWFLFGGILGDDRTAQLRVCGFPSRHLGPIQMTTDTALAVTKRVVE-DRQLPWTVKPELVFSEKVEMPFRYLQPIMPDGMKELIHKDLDRA-FE Punst1 LPEWVELEYKHMVHFTHLSDQVCLLDPKATSALTPEDGFSCFLFGGILGDDRTSELRVLGFPTRHLGSIQMTTDTALGVTKKVVD-DKKIPYIDYPTITFSESVEMPFRYMKPLLPPGMKDHLKKDLDQS-FE Rhior3 IHEWCSLEYKHMLYFTSLTEEICLLDPGASSELKPEDGFKYFLFGGILGDDRTGELRKLGFEGRRLGPLQMTTDTAVNVTKIIVE-DK----------------SM--------------------------- Rhoto1 FPHWIALEYAQMVIFSSLSEKVCLLDPRAEKEIAPEDGYDWFLFGGILGDDRTGILRRDGYPGRHLGPVQMTTDTALGVTSLIVSPPHTITFVDHPTIRFDEGVEMPFRYIEPVLPEGMREHLKADMDRG-LD Rozal11 ------------------------------------------------------------------------------------------------------------------------------------- Sacce1 FSEWVILEYSQILILSSLPGRVCLLDPRATIDLQPEDAFDYFVFGGILGDDRTKELKTAYLISRRLGDKQMTTDTAIRTTQLIIK-DRDIKFIDYPEFRFNEATEMPFRYVKPILPEGMLDLIKKDSAQS-LD Salro ------------------------------------------------------------------------------------------------------------------------------------- Schco3 IPPWVELEYSHMVHFTNLSDSVCLLDPKAEKELSPEDGFEWFLFGGILGDDRTAELRKLGFPARRLGPIQMTTDTALGVTKIVVG-DKEIPYVDMPTIRFNESVEMPFRYIEPVLPPGMKELLHDDLNKS-FD Schpo1 ------------------------------------------------------------------------------------------------------------------------------------- Sorma LGPWSELEYLAIFHLTSLPSRVCLLDPAAKKDLSPEDGFDVFLFG-----DRTSELRKKGFEGRRLGPVQMTTDTAVRVTRLVVE-GKKIPYVDHPELKFSESTQMPFRYVKPIMPEGMVELIKNDTDKA-ID Sphar VGKWCVCEYTHMLIISNVNSRVCLLDLRADKELSPEDLFDAVVFGGILGDDRTGCLRTHGFTTRVLGNRQMSTDTAVLVCKTILE-DGEIEFIDDIELKTGDSTLLPYRYVKPLLADGLIEILRDDEENC-LF Spipu1 LDEWSELEYANILYLTHVHAKVILLDPSATQPLEPSDGFKWLLFGGILGDDRTKELRKLGFTTRHLGPVQMTTDTAVIVAKHVIE-GKKLEYVDRPEIRLGETVELPFRYLKPQLPNGLLELLKKSNEIS-LV Sporo1 FPHWIALEYAQMVIFSSLSGKVCLLDPRAEKVVGPEDGFEWFLFGGILGDDRTGILRKDGYPSRHLGPVQMTTDTALGVTKLCVQ-DGEIKFVDHPTIKFPESVEMPFRYVEPILPEGMREHLRDDMDRE-LD Stehi1 LPRWVELEYNHMVKFTHLSENVCLLDPKAETELSPEDGFAGFLFGGILGDDRTSELRALGFPGRRLGPVQMTTDTALGVTKLVVQ-DKKIPYVDFPTVTFNESVEMPFRYITPKMPPGMKEHLYEDLNQS-FE Tapde11 ------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------- Treme1 -------------------HRVCLLDPKATLPLSPEDKFSVFLYGGILGDDRTSELRKLGYEGRHLGEKQMTTDTAVLVTKLIVE-DGQIPYVDFPTISFSESVEMPFRYVQPILPPGMKQHLKEDLNRT-ID Trire2 LGPWSELEYLAIFILSCLPSRVCLLDPAAAKDLAPEDGFDAFLFGGILGDDRTSELRKKGFEGRRLGPVQMTTDTAVRVTRMVVQ-DKEVPYLDFPELQFNESTQMPFRYVKPIMPKGMVELIQKDADKS-LD Umbra1 MHEWCTLEYKHMLYFSGLSEDVCLLDPQGKQELSPEDGFKYFLFGGILGDDRTKELRKLGFEGRRLGPVQMTTDTAVNVTKRVVV-DKEIPYIDHPEIFFSESVTMPFRYIKPLMPPGMLELIKKDNEMS-LD Ustma22 FPEWALLEYRHMVHFTSLSDKVCLLDPKATYAIKPSSAFEMFLFGGILGDDRTSSLRQLGFPSRHLGSIQMTTDTALGVTKRCVE-DLRLQWLDHPELHFGESVQMPFRYMMPLMPQGMLQLIHKDLGRS-FE Walse1 IPEWSLREYRNMVIYTNLSDKVCLLDPKAEEEIKPEDLFSHFVFGGILGDDRTKELRKYGFPGRHLGARQMSTDTALGTTKRVIV-DKEIDFIDDPTIVFTESVDMPYRYLKPLMAPGMLEHIRKDLDKS-FD Zygro1 FSEWVTLEYAQILILSSLPGRVCLLDPRASQDIQPDESFDYFVFGGILGDDRTSEIKNQYVVGRRLGDKQMTTDTAVRTTQLIVE-KKKIRFIDYPEFRFNEATEMPFRYVEPILPAGMMELIKKDSEQS-LD [Cluster3232.fasta_al_trimmed; alignment length = 682] Allma1 KATTIDELKINLAELTHQKTGAKVLHFDR-DDPNNVFAVGFRTPVTDSTGLPHILEHTTL--CGSAKYPVRDPF--FKMLQRSLSTYMNAWTAHDYTLYPFSTQNLADHRNLMNIYLDAVFHPKLTDFSQEGWRLESP--LVFKGVVYNEMKGAMADQSLFPNSGGDPAVI-PSLKYEDLVAFHRRYYRPENARFFVYGSAPITLEHIDRISSIEPKTVKATCARMCIAWGVYTTAAMKVLSSLLLDGSSSPMQQALI-DSGLAPDYSPVIGYDSSLRFGIGVQGIEQIPVVIWDVLNKETGFPKERIDAIVHQTELSLRHVTAQFGLGLLQGVVFQGTDAVEMRRIHDEAVNLFQRLVRTYLLENVTLIME-PDANLTANQATDEAARLAERVEVLTDADRKAIYERGLDLAAAQNSEDLSVLPCLSLDEVPLESE-TNGVTYLRLQTVLPLLPLFSSALTWQ-GTEQLDQEIKLLTGGVSLGMGGSVLTRQAEHLARLMPELLFGTAFDRVDRLQTLVNSIVSAGHRFAAVAQVTGISQLRFLHALQSVETVVPQLEAIAAALPTVPFMSMALAVAGNLATHGYLHREVREKGGAYGAGANHAGVYSLFSYATLEHFTTSFRALKLSLLGDMDMDAGAQGAGEFAQPLTKAVRQRRDALRNVTREDVARVAETYLVVLGP Ashgo11 RAQEIPEMRMAAVELEHEMTGARHLHLER-EDQNNVFSVGFRTPPPDATGVPHILEHTTL--CGSQKYPVRDPF--FKMLNRSLANFMNAMTAHDHTFYPFATTNQKDFANLRDLYLDATLRPLLRDFLQEGWRLESE--LVFKGVVYNEMKGQVSNEAIYPASGGDPEHI-TDLSYEDLVAFHQNHYHPSNAKTFTYGNFPLTLRKLDDFRGFGAVSVEEPCQRTSMTWIVYETFLLKILGSLLFDGHSSAFYKKLVEETGLAYELSVNTGVESQTALTVGVQGCTDVGQVIMETFTAAQPFEKHRVEAILHQLELSKKDQKSDFGLQLLYGIWVNNTDPFDLQRFRADWDRLFQRLLNKYVIGKFTFTMV-GSSDFNQVKDQNEQSKLKAKVSSLTESDKEVIYKRGLHLQELQNSQDLSKLPTLTTADIPHSTD-TNGITYIRMKRPLPYIPLYSDGLMNI-GTSAIEEQIRLHTGGISLEISACALNSKTQYVFDIINKIMNETALSVRSKMKVLISYAAENGHDLATGAHFSGIEQVRHMNNLMSNT-VLQNLEAMAQSTQGVSYTHAHLQVLASLLTFKHLHREVREKGGAYGGGATYNGIFNFFSYRSLNIFRNAGKYVKLSIFQRVDASPSSEGLLQFRHNISDEQRDRRQQLLKSTLDDVRRVADIYLAVVGP Aspfu1 EKKHVPELHLTAVRLKHDKTDADYLHVAR-EDKNNVFGIGFKTNPPDATGVPHILEHTTL--CGSEKYPIRDPF--FKMLPRSLSNFMNAFTSADHTTYPFATTNRQDFQNLLSVYLDATLHPLLKDFRQEGWRLGED--VVFKGVVYNEMKGQISDESICPSSGGDPQYI-TDLTHQQLVDFSKRNYHPSNAKILTYGDMPLHLKQIGELDGFEPLNVTVPGPKTSTSWYVVETFSVGILSSLLLDGYGSPMYRALI-EGGLGSSFTPNTGLDSSGRFSVGLTGVADAPKVIKRVFEESSGFNDEKVQGFLHQLELALRHKTANFGIGVMEKTWFNGSNPMKIDEFKKKYEQYLESLMQKYLMNDLTFTMV-GTPSYNKDLDDQEMVRKEKKLSELVEQAVSALAEEELQLLKIQEEADLSCLPSLRVEDISREAP-TNGLTYFQALNSFLLLPLFNDCIMRL-GTEQWEDLIKLKTGGITLQFSGYALDNNIPDMLQILTTLVTETDFTSPHMIQELLDAVAGSGHRYAAAAGLSGLAQLQATANLLRLAELIDKLRLIGLAMQTVPFIDAPLSVLSQLLTHKYLHPEIREKGGAYGAGASNGGFFAFTSYNSLKVFQNSGIFAKLGIFQGLDASVDEEGARYFMSGVTHEMDQWREQVLDVTAKDVNEVAQKFLCLLGE Aurde31 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 QTRFLKDYDCESQWFKHSRTGADWIHLKK-SDTNNVFMVGFQTDVTDSTGVPHILEHTTL--CGSKRYPARDGLS-IHPLNRLYCESNTIVKCDDLTVYPFSTENKTDYYNLMNVYMDAVFAPRLRDFMQEGWRLETP--IIFKGVVYNEMKGALADQALYRDSGGDPENI-TDLTHEQLLQFHAKNYHPSNARFFTYGSFPLQMQKVDELSGFSPKTIQAVGPRVAVSYLLEESLSMRILVNLLTDGAASPMYTSLI-ESGLGSDYAPTTGHSQFACTSFGLTGMKNIPVAIQYVLEKQTGFPENRINNIFHQIELGLKHRTASFGMNLGWNIMIHGGNPLDLAKLKSDLSQFLQNLVETQLLSNLTYIMN-PDAGYPASLIEKESQRLAKHVDALTDSDRENIKSDGLELLKLQETEDLSCLPCLSLSAVKKQTQ-TNGVSYVYLKWDVLLAPLMCNSLTSL-GTGELDETIRAHTAGISLVLNASALDSNIDAMYNLVLEVLQTTNWAAYDNLNIALNSVPNSGHAYAAAGLLKGMHQVEFLDQLLKIPALAKELETLARSVSTVSYVHASLKVLASLMSTHYMHRELREKGGAYGGGASYNGVLSFMSYRTLDAYERSVAWAKLEAFRNMDKDAAGEGLTQFQYGLDLFALQHRDALFKVTMQDVERVAKIYLSVIGE Botbo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 RSKHVQELELTALHLKHDKTGADYLHVAR-EDKNNVFSIGFKTNPPDDTGVPHILEHTTL--CGSKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 QTSPIPEFSLTAVSLKHTESGATHLHLDSPNDSNNVFSIAFKTNPPDNTGVPHILEHTTL--CGSKKFPVRDPF--FKMTNRSLSNFMNAMTGHDYTFYPFATTNSKDFENLMDVYLSSVFEPQLNDFLQEGWRIESK--LEFKGVVYNEMKGQYSNESIYPSSGGDPKKI-VDLSYEGLLEFHSKNYHPSNAKTFTYGKLPLSLSKISKYESFEIFDVTIPGPCTSITWNQYDIFKWKILSSLLFDGHNSPFYQELI-ESGYGDDFSANTGLDSTTAFTVGLNYLQKVDNFVMEIINNSSSY-HGRIDAILHQIEIGFKRHKPDFGFGLLSSIWVNGVDPIDLSHFKEDYKQIFKELLEKTLCNPFKFTME-PREDFTKQLVKDENLMIEKRVSELTEDNKKAIYEQNLELAKLQLEQNTEVLPTLTIDDIPKRVD-TNGLVYANALKDIKYLPLFNNCLTNLAGTTELETKIQMLTGGITYVLSGMALKEKSSSVYDLWLEILTTTKFDTSDKLSVLINNIADRGHSYASSSKLTGLSQVQFVMELNSAKEIIPILQEISLGKIGSSYSSASLQILSQLYSFKNLHSKIRESNGAYGGGLTYDGTLNFYSYKSIQTFRDSLSYGKLRVFQSVDANISSQGASAFFENIDDYLRQRRENFLGTTLKDLRDVTEKYLTVIGD Cangl RAVPVPELKLTAVDLIHEQTGAEHLHIDR-DDKNNVFSIAFRTLPPDATGVPHILEHTTL--CGSEKYPVRDPF--FKMLNKSLANFMNAMTGPDYTFFPFATTNARDFVNLRDVYLNSTLRPLLKDFYQEGWRLESD--IIFKGVVFNEMKGQVSNQNIYPSSGGDPQKI-TDLHYQDLVDFHHANYHPSNARTFTYGSFPLTLKKVNEFRAYGTKELTLEGQKTSLTWKLYETFLLKILGNLLLDGHDSIMYKGLI-ESGLGHDFSVNTGVESMTALTVGIQGSQNVEEFVFDLFKEENDVDSNKVDAIIHQLELSKKDQKADFGLQILYSIWTNGIDPIEIGRLKSDFKEIFKNILDKYIIDQFHFTMK-GSEEFSSKLAAEESTKLDKKLKELDETDRKAIFERGLLLEAAQNHEDLSCLPTLGVADISRKTA-TNGISYIRGKKLIPFLSLFAASLTHL-GTGAIDNEIKLHTGGISFDMSGFSLNEKSDYIFNFLKTILMETDFSTHKKLKVLISHIADSGHTVAASGHLSGVEHYKLISRLCSQSEVIDKLVMLAQAYNGVSYTHAALQVLANMLTFKHLHKEIREKGGAYGGGATFSGIFSYYSYASIQTFEKSASYVKLSIFQQVDASPKSEGSTFFNLGVTDEMRQRREQLLDTSLLDIHRVAERYITVVGP Capow DIQLVKEFSLTAVHLTHDATGADYVHMAR-NDSNNVFAVSFRTAVANSTGVPHILEHTTL--CGSNRFPCRDPF--FKMLNRSLATFMNAWTASDYTMYPFSTQNGQDYRNLLSVYLDATFFPLLRDFAQEGWRVESP--LVFKGVVYNEMKGALSDQALYPTSGGDPPAI-TDLSYDDLIAFHRDHYHPSNALFFSYGDLALHLELVQRLCHFGPRTVQLSCPVVSVAWVVYDTLVARIVGATLAGGPSTPFYRALL-ESGLGLAFSPNTGCSTSEQFAVGLKDVADADAIIDDTLSHVHGIDAKLVEGELHQLEITLKHQSSNFGLSLASMLWVQHIPMQEIARFRHEFATFIQRFVRRHLLTNLVAVMS-PDAGYQAGLLKEESERLARHVALLDDAAKEKLHQQGLELQQQQNREDLSCLPIIRVDDVERKQP-TNGVSYLHGIITYPYLPLFMEVLTAM-GAREFSNATQTVSGGTHVLFASHFLDRYADRALDLFSTAMLRPRLDDPKRL-VMLNSIADSGHQYAAARNLSGITQLQFIRSLEQTEKVLALLRDLALAFPSVPATHVPLQILARILTHNFLLREVREKGGAYGAGANAGGVFTFYSYGTFDSFHDAIQWVKLSILAAVDSSPGKRGMGLFLSGYTREMRQARDAIFATTIADVQRVAQQYLAVVGP Catan2 RTTAVPELRIDVAELSHNSTGAKYTHFAR-DDANNAFAVGFRTPVNDSTGVPHILEHTTL--CGSKKYPVRDPF--FKMLQRSLSTFMNAMTYQDLTLYPFSTMNKTDYRNLMSVYMDAVFQPNLRDFAQEGWRLESP--IEFKGVVYNEMKGAMSGRHLFPDSGGDPKNI-TDLTWEQLVEFHHKHYAPANAHFFSYGNFNLTLDYVNQLESL-PKTVHETAMRFCLAWGVYTNTALSILSKLLLDGSSSPMQQALI-DSGLAPDYSPAIGYDPSTRFAIGVQGIDQIPQVIWRVLRSETGFPKERVDAVIHQMELGMRHVTASFGMNLVQNMIFHGSDMADLARLHDEAVNLFQTLIKQYLLDNVSLTMT-PDAQFPAQVAAEEAQRLQWHVAKLTDEDRQRIHAEGLELVKAQETQDISVLPCLTLSEVPKEAP-TNGITYLAAVADLPYLPLFTSALTWQ-GTEELDQEMRLYTGGIGLSIGGNALTKNVPHLTRLMSELTFQTKFDRIDRLQNLINGIAHRGHSLAAASKLLGLSQLQFLSGLQAIEDVVPKLEAIALAIPTVPYTSMALNLAGSLATHQFLHREIREKGGAYGGGATHNGAFLMYSYETMHDFERAIEWLKLGMFGSMDADVGSQGSTEFAHGITKEMRQRRDALFNVTAQDIVQVAEKYLVILGN Cioin QVEDVPEFSMTAVLLHHNVTGSEHLHLAR-DDKNNVFNVSLRTTPMNSTGVAHVLEHVAL--CGSDRFPVRDPF--FKMLDRSMSTFMNAMTGSDYTMYPFSTQNQTDFRNLMSVYLDSVFFPRIKDFLQEGWRLESP--IVFKGVVFNEMKGVMADSKLLPDSGGDPAHI-PNLTWEDLKQFHASHYHPSNARFITYGDMKLHLGIINDMKKFTPRSHTMHCATYSKSYLIFETFSASVISTLLIDGPTSPFYRNLI-ESGIGSDYSPMTGYHNYQKFSVGLQGIGDVTKVIQDTFMEKNGFSKERIEAILHRVELQYKHQSSRFGLGLTFSLWQHGTDPVDVNKFRQKLDSFLQKKCEEYFVNNLNLTMT-PDPGYKVSLEKSEEEQLQSMLGKLSEKDKSQVYEEGLELSNVQQQEDISCLPTLHVDDIPRKQP-TNGVSYFNAVLPVMFLPLFCDVFTQM-GTASFSQREDLFTGGLSVRLSSHCLERNLEQMFQLWAELFNEVNLNDATRLQTLINGVAFSGHMFAAAMNLAGLTQVNLMKKVADIDDVIMKLNQISMCIPTAPYSHPTLRILGRLMTTKFLHKHIRYRNGAYGGG--------------------------------------------------------------------------------- CocheC53 RVKQVPELELTALHLQHDKTGAEYLHIAR-DDTNNVFSIGFKTNPPDATGVPHILEHTTL-------YPIRDPF--FKMLPRSLSNFMNAWTFADHTGYPFATTNAQDFKNLMSVYLDATLHPLLKDFTQEGWRLGKR--IVFKGVVYNEMKGQMSDEHLYPASGGDPQKI-TDLSWEQLRKFHADHYHPSNAKILTYGDMPLHLKEVDSLSSFGPKNVTVPGPKTSVTWLAVENFALGVLSSLLMSGYGSPLYRNLV-ESGLGADFSANTGYDSAGRFSIGLDAVDDVPKVIAETLLEKNGFDKIKVDGILHQLELSLKHKTASFGMGILQRLWFNGIDPINVDAFQNKYAEYLESLIEKYLLTDLTFTMQ-PSETFSQELVDEESQRLAAKIAETTQEAQKYLEDRELQLLQVQEEEDLSCLPSVHVEDIPREAP-TNGLTYFRAVHRLEMIPLFTSAIMRL-GTEQLEEQIKLKTGGITMAFSGYAFDRNIPDMYELLRTIIQETDFDGPEKIRELLSSIAESGHSYAAEAGITGLTQIKLMTALASLSDVIQKLKAIARAVPTVPYTHAPLEILSKMLTFKQLHPEIREKGGAYGGGAYARGLFGMYSYNSMKIMAEAGQWAKLSAFQGHDASVSREGMREFLSGVTDDMLQRRERLLDVTAEQVQAVADEFLAILGE Coere1 -SKTVGELKLRAFRLKHQRTGAEWLHIAR-EDSNNAFSIGFTTSPSDSTGVAHILEHTTL--CGSVRYPVRDPF--FKMLSRSMSTYMNAWTAHDYTQYPFATQNAKDYENLQGVYLDAAFRPLLRDFRQEGWRLESS--WGIKGVVYNEMKGAFSDQQFFPGSGGDPQFI-PDLTHEQLVEFHRARYHPSNARVYSYGDLPLQLARVDKIAQFELRKVTEFGPKFSVSYLVQETFGMSIFSGLLLNGTSAPMHQALI-DSHMGSGYSANTGYAPFTRLAVGLQGIKDIELAIAETFAREEGFERRRVDAALAGVELAYKHRAADFGLSLMRSVWFHGVDPITVAQLRSTIDSFFEGIVNRYFTQSLRYVML-ADPAYGQQLDTRENELIQTKVAGLGRRELEKIDAKNSELAAEQAKEDVGALPTLTLSDVAERTT-TNGISYLRVINDVPYMPLFCEALTYL-GTAQIETDIGLHTGGISISFGSHCLDQHIASMYELVLELVRETNFSNTGRLRALVNEVADSGHAFAAGSTLTGISQVRFLSGLARLEPVSERLRQVAQAVRTVPYTHVRLQVLAKLLTPNYLHREIRERNGAYGGGAVYSGLFSFFSYATIATFDKAVDWIKLSVFGDLDTSVADEGMAYFTAGISDDMRQRREQFFEVTKSDLKDVANKYLAVIGE Conco1 ENRDIKSLGLTGVVLEHQKSGAQLLHLAKEDESNNVFSIGFPTLNNTSDGVAHILEHTTL--CGSQTYPVRDPF--FKMMPRSLATYMNAWTANDFTQYPFSTQNPTDYYNLMSVYLDSVFKPILSDFSQEGWRIENE--WEFKGIVFNEMKGVFSDKHLYEGSGGHPLNI-PELTWEHLKKFHDDHYHPNNAKIFTFGNFPLHLSKLNETHTLEPRKVVVKGPKISVSWLTFTTMSLGLLFSLLTGTSGAPLQKALL-DTHLGTEYSPTTGYNAQSPLSIGVQGVSNLEKIIYETLETKEGFSKDLIEGALLNIELSFRHRGSNFGIRLVQSIWNYGLNPLDLAKLRSEIAKFFEGLIRKYLLDNLIYIAE-PSKEFEQQIQQQENSMLKDIVKNKVEKDETTIQEFNAELQRRQMSEDLSCLPTLTIDDIQKNTN-TNGISYLKIRQSLPFVPLLCECLSFL-GCAELDEEILLSTGGISVTFASHALNDKSSEMYRLMTKILLETNFDQPDRIKTLIGSVADSGHTFAASGILSGMYQTRFMTYLANLPQITQHLKSLSRALSTVPFQDPHYQILSTLLTHLYLHREIREKGGAYGGGATHDGTLSFYSYNCEQVYKQSLEWAKLSVFQSIDHSASQEGLSEWTSGITLDMAKRRHTFLTAKETDLKVIAEKLLVIIGQ Conpu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 RTKHVPELELTALHLQHDKTGAEHLHIAR-DDSNNVFSIGFKTNPPDDTGVPHILEHTTL--CGSEKYPIRDPF--FKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDATLHPLLKDFTQEGWRIGRK--LVFKGVVYNEMKGQMSDDYIFPDSGGDPQKI-TDLTYQQLKQFHDEHYHPSNAKLFTYGDMPLHLQEIDALQAFEPEEVTLEGPKTSVSWVIVESFSLSLVSALLMDGYGSPLYKGLI-ESGLGIDWSPNTGYDSGNAFSVGLTGVSDVPKVLQKILREQKGFERSKIDGYLHQLELGLKHKTANFGMSMLHRLWFTGIDPFDRAAFEAELAKYLEGLMDKYLLNDLTFTMS-PSPTFGLELVQEEADRLATKIEAVKEAAQKALEERELELLEEQGKEDLSCLPSVHVKDIPRQAP-TNGLTYFRLLNILSLVPLFTGAIMRL-GTEELEDLIKLKTGGVSFGFTGMALDRNVPHIFELLRKLVVETNFDSPEQIRQLINDIASSGHSYAAEAGLTGLSQVRLMTSLASLEDVMAKLKQIALSLPTVSYKSAPLQILSQLLTHKHLHHEIREKGGAYGGGAYHRGLFGFYSYNTLSIMRRAGQWAKISVFQGVDASVNEEGMGRFVYGIDEAMRQRREQLLDVTKEQVRTVAQKYIVFLGE Debha1 QVQPIPEFSLVAVKLKHSRTGSEHLHLDTPNDKNNVFLVAFKTNAPDATGVPHILEHTTL--CGSFKYPVRDPF--FKMLNRSLSNFMNAMTGHDYTYYPFATTNAKDFENLMDVYLSSVFEPLLTSFMQEGWRLESP--IIFKGVVYNEMKGQYSNEAIYGSSGGNPNEI-TDLRYEDLVDFHSSNYHPSNAKTFTYGNIELHLNKLNEFESFGESDVTVKGPKSSITWVLYDVFKWKVLSSLLCDGHNSPFYQELI-EKEYGEDFAVNYGLDATTAFTIGLNNLEKAKNLVRGIFVEESGF-NDRIEAILHQIELNFKNHKPEFGIGLLSSVWVNGLNPVKLNRFKEDYKLMFQDLLDESVLKDFKFTME-PDESFGKNLTSQETERLNKKIEALTEEDKEIIYKRSIELAEKQKKEDVSALPTLTVKDIPREVD-TNGLIYMNATKDIEYLPLFDCCLTNLAGTTELEIKIQKLTGGVTFMLSGMALKDKSQNVYDLWFEILTQTKFDSEDKLFTLVNTIADSGHSYASNSQLTGIGQVSFILDLNRKKELLPVLKDISLAKLGAAYTSAALRVLSQLLTFKHLHSVIREANGAYGGGLLFDGCLNFYSYTSVQSFKDSTSVAKLTIFQGVDAHISLQGSLDFLEHITDEMRQRRERFLDVTYEDLKNVTEKYLTVIGD Dekbr2 RVQQVPEFNMTAVELTHKISGSKHLHIER-QDRNNVFGVVVKTNSPDDSGLPHMLEHTTL--CGSDKFPVRDPF--FKMLNRSLANFMNAMTGHDYTYFPFATTNKVDFENLMDVYLDSVFHPLLNDFRQEGWRLESP--SKFKGVVYNEMKGQISDQNIYPSSGGNPAEI-VNSYYDDLLDFHSRQYHPSNCWTYTYGSLPLSLGKIDKFATFGCKYVEITGPKSSLTWYIYESFKIKILSTLLMDGHSSPLYKGLI-EQGIGTSFSANSGMDALAAFSVGLNGLDQAAKLVLDILKQQSGFPENRVKGILYQLDLGRKIENANFGLNSLSALLVDGIDPLSLDKFRKEYKAVFADSIQKYMLESFKYTMR-PDANVPERLAQAEEKSLKEREERMTSGDKEIIYNKGLELEKFQKNEDLSCLPTLHSGDIERESPKTNGVTYFRALKSLKYLPLFSTCLTNL-GTSEIEDEVKLYTAGLGFTINSACLDKNTPKMLSIWENLLLETNFRNIEKLKTLVSAIVSSGHSFAASSKLTGIKQVKFLNSLSSEKDVVPKLEEISSVLRGSDYCSASLQLLSQLLTFKYLHKNIREQGGAYGGGASYDGLFSFYSYESENKFVASTKFIKLTIFQKIDAAVGEEGLPYFNFDVDDDARQRRENLLDCSLADIQNVANEYFVIIGS Dicdi KIREVPERQFKTYQFEHIETGAKYLHIDC-EDTNNVFSVTFKTIPKDSTGVAHILEHTTL--CGSKKYPVRDPF--FNMLKRSLNTYMNAWTAPDHTSYPFGTQDPKDYYNLLSVYLDATFFPNLSDFRQEGHRLESP--LKFKGIVFNEMKGALSDQHLYPGSGGEPNDI-PSLTYQQLKDFHSNHYHPSNSYFFSYGDLNPHLKFINDLSKFKSKRIYLKCPKFSISILLFESLSLHMLSNLLLRGSNTPMYQALL-ESGLVLDYSPNTGFDDGLLFSVGGIGIEDLEKVIIETLEKRDGFASDVIESILHQYEFAQKDVSASFGLKLVGSLWIHGGDPVDIAKLRKELEKFFETKIKE-LLNNLYITME-NDENLQKEEQEKELQKLERIKSELTPEQTKEIIEVAKDLQFRQNQQDVSVLPKINICDIEKQLP-TNGISYFRSTIDIPYVPIFCSLIDEM-GAKQLDTEINLHIGKFSIYIKGAALNNNLLKMFSLLQKILLENKWNNPDLLKNLLEGIPSSGLSYASSSKFSGLSQVRLINEIVSINSLINKLLAISKTYQAVPYTHAPIQILTKVLS-EFLHKEIREKGGAYGGGSSVDGVISFYSYKTLDAFDQSIQWSQLSIFSDFDSSPSNKGVGEWMRDITNEMKQRRNNLLSITKPKLEEIATKYLTVLGS Dmel RVEHISEFELTSYTFRYERTGTELWHIDR-NDSNNVFSINFRTTPFDSTGLPHILEHLSL--CGSQKYPVRDPF--FKMLNRSVATFMNAMTGPDYTIYPFSTMNEIDFRNLQHIYLDAVFRPNLADFLQEGWRLESK--LVIKGVVYNEMKGAFSENNIFPDSGGNPLEI-PKLAYNDLVEFHKKYYHPSNARIYSYGLFDATLALLDELSDQSPRLVHISSRQIAIALLIQESFELHVLSEVLIRGPNSPFYKNLI-EPNFSGGYNQTTGYSSDTKFVVGLQDLEDFKKCFDKTIINNDGFDSQHVESVLHNLELSLKHQNPNFGNTLLFNSWNHDGDVVSISGLRESISQYFQEKIEKYFANNLTLTMS-PDEAYEDKFKQAELELVEQKVKLLDEVKIEKIYERGLILDSYQKASNTDLLPCLTMNDVRDPVP-TNEITYFKCMFNIQLMPLFCNVISAM-GTREFDKHILLKTGGFDVMINTHALNNNVPEMFALCQELIKNVRFDDSERLKMLIVGVASSGHLYAATSQVCGVDHIDFMKNFVHTVDICDKLSTIAKALFTVPYLHPTLRVLAKLLSAKYLLPVIREKNGAYGAGAKISGIFSFYSYKTLNAFDETYKWLKLGVLQQLDTAPGNIGIDYFLYEVSQEDFEYRSRMLSVTIDDLQCAIENYFCILGP Enthi YREKLPDYNITGIVFEHNETKAKVIKILS-DDKNKSFSISFKTPPTNNKGIPHIIEHSCL--SGSDHYTTKEPF--ADLLRGSLQNFLNAITFPDHTMYPIATTNEIDYKNLMKVYLDAVFLPRVRPFYQEGRRWEGE--LGFNGIVYNEMKESETNQKLYDGSGGIPKDI-ETLTYDEFLKFYKEHYHPSNSLTVLYSPLTLELTVLNEGKGFKDKDTNISGTVFVYAWKPEVQFALNIIQQLLVTVEGAPLNEKLK-ELGIAKNVIGQFEIDYKT-FSVVAKNASKLDQFVNEELQKKDGFDKQRAIGILNKHEFDLKECT--FGKGLVYAMYAHAHDDTDITKVREGLKNYLEDIVQKYLIENIVVRCV-PTKGLTETWEKESKERHSEMSKDFDEKAIKEIENTCAELKRRQQAEQIATIPHLRLSDIDKKVDVTNGIVYFKYFFDLRVADFLASVIKSF-NTLTLGSLIDINFGKLTFLISGKVLNGYITDGIQILAEILNDIQFDVKIKLSEFIDVIKNASYYPLIKSYLSGITSYLEDVKLRN--AFLHSLEEMGKGFNFVTFNG--FKALLEIIEKEYLWNKVRVEGGAYGSWMSYSGNAIFTSYETLITYDKVVDYLLIGIFADIDATIS--G---FFNTLNNTLGSIREQLFQVTLESLKEQSSIIICTISP Falba GAVRLPAFDAAAVHLRHVATGAEHVHIAR-DDPNNSFSVAFKTPPYDSSGTPHILEHVTL--CGSAKYPVRDPF--MKMLTRSVANFINAMTDNDLTMYPFSTHNPQDYRNLMSVYLDSTFFPRLADFRQEGWRLESP--IVFKGVVFNEMKGVMSDSQLFLGSGGEPAVI-PELTHEQLVDFHKKCYQPSNARFYTYGALPLILQQIQT-EVFDPRTVEVGYPYVSVAFVCYASFEMRVLSDLLTSGPTSPMYKALI-ESDIGSDFAPGVGVSSQQRIAIGVRGVAECDKVIFDTLRDKTGFPAERIEAVMHQMELSLKHQSTEFGLNLGLGLWIHGASPLTGDRPRAALQEHLLKLLRKQLLENVTLVMS-PDVGMKQRQAEAEMELLQGRLLQLSASDKGRIFEEGLKLKKLQESQDISILPNIQLEDMPSRQP-TNGVVYLNTIQTLPYLPIYAQALTFM-STGQVSDDIDLYTGGLSLASSTFALSRNVPQMMDLKVDTGLQTDFSDRQRLRHLVEQLSRSGHSIAAASLLDGCDQLALLDVLSQMDRLAETLLQIARVFQTAPASAAALEQLCQMLSRQFLHREIREKGGAYGSGAYFDGLLVMTSYETLNVFDQAHDWLKLALLGSLDSSPSARAVDLFRGAVSEAIQQMRQAIFDLSAEELRDVYRQYVAVLGD Fomme1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 RSKHVPELELTALHLQHDKTGADYLHIAR-DDSNNVFSIGFKTNPPDDTGIPHILEHTTL--CGSEKYPIRDPF--FKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDSTLHPLLKDFTQEGWRIGKK--LVFKGVVYNEMKGQMSDDHIFPDSGGDPQKI-TDLTYEQLQKFHAEHYHPSNAKVFTYGDMPLHLKQVDTLQAFEPKEVTLYGPKTSVSWIVLESFSLALLSTLLMDGYGSPLYRGLI-EAGMGADWSPNAGYDSSAKFSIGLTGVGDVPKLVQQILRDNKGFDKTKIDGSLHQLELSLKHKTANFGFSMLNRLWFNGVDPFDINGFQAKMAEYLEGLIDKYLLNDLTFTMA-PSTTYGEDLVKEEQERLSTRIQAAIEKARKHFEKQEQELLVEQNKEDLGCLPTVHVKDIPRSAP-TNGLTYFRAINTLELVPLFTDSIMRL-GTEQLEDLIKLKTGGVSIIFTGMALDHNVPVMFDIIQKLVLGTDFDSPERIRQLLNDIASTGHRFAAESGLTGLSQVQLVTSLASLEDVISKLKQIGLSLPTTSYTSAPLQILSQLLTHKHLHHEIREKGGAYGGGAYSRGLFGFYSYNTLSIMRNAGQWAKISVFQGVDASVNQEGMGRFLSGITEEMKQKREQFLDVTKDQVREAAQRYLAFLGE Galma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 QINHIPELELTATQLIHEKTGASHLHIAR-DDNNNVFGVGFSTPPMNSSGTPHILEHTTL--CGSKRFPVRDPF--FKMLNRTLANFMNAMT---------------------DVYMDATFHPYLRDFKQEGWRLETP--LQFKGVVYNEMKGVMSDENMFSGSGGDPKYI-TDLTYQELLQFHKTHYHPSNAKFYTYGNFPLHLATINNIRGFE--------SKMSMSFLTFETFVLKIFSYLLLDGHASPMYKALI-DGNIGSDFSENTGYDSSTKMSIGLQGMKYVPLAINKVLEDQNGFDSKRIEAAIHQTELSIKHKTASFGLSLMHLIWFNGSNPAEIKLLREKLKTFFQNLVKKYFINNLISVMT-PDSSYTEKLLKEEQSRLDAKTSTLTSEEKEKVYMQSIELLKKQEEEDLSVLPSLKIQDIDKQTS-TNEITYFRIINKIIYLPLFAQALTSL-GTAVIDDDIRLYTGGINLLITSHSLDRNINHMYDILKQLLCETNFDNVDKLRTIINSVVESGHQYAAGSKLIGMTQVHFMNKLAAFDTIIQKLKEIAQAFKGVPYTHAKLQILSSLMRTHYLHREIRERNGAYGGGATYNGIFSFFSYETLKTYRDSIEWVKLSTFKKIDESVSEEGMNYFTGKITDEQRQRREQLLAVTEDDVKEVAKIYLAIIGE Hisca1 EKKHVPELHLTAVLLKHDKTEAEYLHVAR-DDKNNVFGIGFKTNPPDATGVPHILEHTTL--CGSEKYPVRDPF--FKMLPRSLSNFMNAFTSSDHTTYPFATTNKQDFQNLLSVYLDATLHPLLKDFRQEGWRLGDD--IVFKGVVYNEMKGQMSDEQIFPASGGDPQYI-TDLTHRQLVEFSKKNYHPSNAKIFTYGDMPLHLKQVGRLDGFEPLSVTIPGPKTSLSWPIVETFSMGVLSSLLLDGYGSPMYKTLV-ESEIGSSFTPNTGLDTSGRFSVGVNGVKDVALVVQTVFQEATGFNDEKVKGILHQLELALRHKTANFGIGIMEKTWFNGSNPMKINEFKERYEKYLEQLMQKYFMTDMTFTMA-GSPSYNKQLDEMEVARKEAKMAELTEKAVDKLKREEFELLKVQEAADLSCLPTLHVKDISRTAP-TNGLSYFQAMNSFLLLPLFNDCIMRL-GTEQWEDLIKLKTGGISLQFSGYSLDKNFSTMLDMMSSLVTETDFNNPVMIQELLDSIAGSGHRYAATSGLSGLAQVQATVRLLHLQELIRKLQMIGLALPTTTFTDASLSVLSQLLTHNYLHQEIREKGGAYGASASSAGYFAFSSYNSLKVFNNSGTFAKLGIFQGLDASIDEEGQRYFMTGVTQEMDQWREQVLDVTAEDVNIAAQKFLCLLGE Klula1 RLLPVPELKLTAVDLLHNQTGSQHLHIDR-DDNNNVFSIGFKTNPPDSTGVPHILEHTTL--CGSHKYPVRDPF--FKMLNRSLANFMNAMTGHDYTFYPFATTNETDFANLRDVYLDATLNPLLNDFLQEGWRLESD--IGFKGVVYNEMKGQVSNESYYPSSGGDPTKM-TDLQYEDLISFHRNNYHPSNAKTFTYGNFDLTLQRLNKYQGYGDVSVETEGQKTSVTWITYQTFLLKILGNLLLDGHSSPFYQKLI-ESGLAYDFSVNTGVESQTAITIGVQGCDEVDSIINKVWEEQNPFEESRIQAIIQQLELSKKDQRADFGLQLLYSVWVNKTDPFDLERFQEDWATLFKDLIKEFVISKFKFTMK-GSETFSQKLDAEEQERLERKLKLLDEEDKKVIFERGKQLQELQDLEDLSCLPSLQISAIPRVTD-TNGITYVRGKRLLPFLPLYADSLTNL-GTSTIEEQIKLHTGGVSFQVDGWALNSKTDHIFKFWKKLLCETDFHKHKKLKVLIASVAETGHAFAGAAHLSGIEQLQLINKLSQEKEVVSKLVELAKCYPGVSYTHAKLQILSNMLTHKYLHREIREKGGAYGGGATYSGTFSFYSYNSLSTFDSVPEFIKLSVFQQVDSSAKNEGTILFHYDVTDEMKQRREQLLDVNLNDIHQVAEEYLSIVGP Lacbi2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele SVEKVQDFNLISLELIHDKTGARHCHVIK-DDSNNCFSVAFATTPKDDSGVAHILEHTVL--CGSTKYPIRDPF--FKMLTRSFSTFMNAFTGPDFTMYPFSTQNKEDFYNILSVYCDAVFFPNLSDFLQEGWRLESE--IKLKGVVLNEMKGYSNNKGLFPSSGGDPLVI-PSLSHEELVNFHRLHYHPSNAIFYTYGNLPLHLKNIGEISQFEPKEITVRGPTVAVSYKRYMNTVMSVITDVFVTGTQSKFYEALI-MSGLGSDFAPGTGYHDYTKFTVGVKGVDNVQKVIESVWRNEKGVEASQVAAVLHQKEISKKHQTSSFGLHLGVGIWLHDTKPAEIKQFKELNSSYIRDIVKEHFIANLTVTLI-PDEEYGKKLVDSENMILHEKTKLLTQEDKEFLQKQALELQSAQDTQDVSCLPCIRLSDVPSNGP-TNGISYLRILISDSLLPLYSNILSAV-GAQDCDLEKMLRTGSFSTLLSSYCLNENIPYMYSLWQDLLNNPNFQEIDRIKAVLDLITSSGHMFASRSYISGLKQTQTVQQFHS--DVQKLANEVARSYRAVPASHPNLTLLSSLLSSKFLHREIREKGGAYGSGAIFSQAFSFFSYKTLSVYDNAVDWAKISVIAKLDAAPGKRGLSTFLGGLSFEERKFRSGLLSATCQDLKEVADIVILLIRQ Monbr VIKQAKPLEITASPL---------------FGLSPTWGCRISWSIPFFVGLSDILAVTPFSRC------FRDRLMLTRAVPRSLSNFMNAFTAPDNTVYPFATTNPQDYVNLMSVYCDAVFFPLLKDFAQEGWRVESP--LEFKGVVFNEMKGALSSQLLHPDSGGEPLHI-LNLTHDELKAFHAQHYHPSNSCFITYGDLLLHLNFLDTLKQFSPRRHVVSCAKLSVAFLAYENFCLRVLSILLTDGNHAPFFQSLI-DQGIGSVFTPNTGFDSSTEFAIGVQGIEQHDQVIDATFAQQEGFEPELVEGILHLLELSQKDVKPHFGLNIATSLLFRGAAFEDIDRFEQDWRQFFQNLIRKHFLNNLTLVMT-PDAHYNTELEQREHAKLQSVLSNLSDQDREHIYQRGLELLEQQNREDVSCLPSLAVEDVER-QP-TNGISYFRMKLPLQLLPLFTTLLTSC-GARDFEKLIRQHTGGLGLELASSALERKLDHMFGLWRDIFADAHVNDMQHLRNTLESVVSTGHVFAAASPISGLTHVLELNRLAALSDVAAELLQMAAAVPGTTYTDAALTLALKIMSLKFLHREIREKGGAYGGGVTQGGAIKFYSYNSFEAFVRSGEWIKLMAFQQLDGSPGRRGRDWFMADIDPTMKQRRERLLDASREDVLRAAQRFLTLATE Morel2 ESRHIKELELDAIRLKHDKTGAEHLHIAR-DDSNNVFGVGFATPPENSAGVPHILEHTTL--CGSRSYPVRDPF--FKMLNRSMATFMNAYTASDYTLYPFSTTNPVDYKNLRNVYMDAAFFPHLRDFKQEGWRLESP--IVFKGIVYNEMKGQMADQYMFPGSGGDPANI-TDLTHAELVHFHKTHYHPSNARFYTYGNFPLSLESINSLQEFSPRRVALTCPKMSVSFLTFDGFGLRILSDLLTDGHASPMYKALI-ESNLGSEYSANTGYDSSTMLAFGVQGMEDIAKVINNVLKKQEGVDPKRIEAIVHQMELGQKHKTSFFGMSLMQGLWFNGCNPVDIERLKTELATFFQNLISKYLLNNLVFTMT-PSPDYGAEVAANETTRLMGKTSVLTNADKEAIYQQGQALLKNQEKEDVSCLPTLKVDDISKKTS-TNGITYFRGISVIQYLPLFTDSLTSL-GTSEIDDEIRLYTGGIRVSFSSYCLDRNQDRMYDLLGSLVRETNFDNVDKLRTLINSVADSGHVFAAGSHLTGMTQVQFMNVLSQLSEVSQRLKEISKCLRGVPYTHAKLQILASLMSNLYLHREIREKNGAYGGGAGYAGLFSFYSYKTLSTYQDSVRWVKLSIFQRMDASAAEEGMVVFTEGITDEMRQHREQLLKVTSADVKDAALRYLCILGD Mucci2 QVRKVPELELTAITLKHEATGAQHLHIDR-DDSNNVFAVGFHTPVSNDTGVPHILEHTTL--CGSQKYPVRDPF--FKMLNRSLATFMNAFTASDYTVYPFATTNPADYNNLRDVYMDAVLHPKLDDFKQEGWRLETP--IQFKGVVYNEMKGQTSDQAMFPGSGGDPKYI-TDLTHQQLLDFHKKHYHPSNARFYTYGNFPLHLAAIGELQGFEPKSVETTCAKLSLSYLTFETFSMRLLSYLLLDGHASPMYKALI-DTNLGSEFSSNTGYDNSTKMSIGLQGVSDVEKVITSVLEQQEGFDPKRIEAAIHQMELSQKHKTADFGLSIMHGIWFNGVDPVDIDRLKSELAKFFQSRIDKYFLQNLSFVMR-PEENYSANLLAEEKDRLAKKVEALTDDDKKQIAQDGKDLLASQDSEDLSCLPSLQLSDIALKTS-TNGITYFRAISTLLYLPLFCDSLLSL-GTAEIDDEIRLYTGGLRIALVGNCLDRNIDKMYTILAKLIHETNFDDVEKLKTLINSIADSGHVFAAGSSLTGMTQVSFMSRLAAMSDVVDKLKQIAKVLRGVPYTHASLQVLSSLMTNHYLHREIREKNGAYGGGARYAGIFSFYSYETLDTYNQSIDWVKLSIFQGIDSSVSEEGMLQFVNGVSDEMRQRREALLKVTQDDIKRVAHEYLALLGE Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSSHCLERNIPMMFSLWQDILNEPEFNNPDRLRTLIQSVAQSGHLYAAAKGLTGLRQVEFMKELSELDGVIENLMKTSKCIRGVPYSHAKLQILLRLMSAKYLHQEIREKGGAYGGGAKIDGVISFYSYSTLNSFEKSVIWAKLSVFSHIDSPPSNRGMPLFKSGLTDEIRQHRDRLFATNRNDLINVSQRYLAIIGP Neucr2 RSKHVPELELTALHLQHDKTGAEHLHIAR-DDSNNVFSIGFKTNPPDDTGVPHILEHTTL--CGSQKYPIRDPF--FKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDATLHPLLKDFTQEGWRIGRK--LVFKGVVYNEMKGQMSDDHIFPDSGGDPQKI-TDLTYQQLKKFHADHYHPSNAKVFTYGDMPLHLKEIGALDVFEPREVKLYGPKTSVSWVVVESFSLALISALLMDGYGSPLYKGLI-ESGLGTDWSPNTGYDSSGKFSIGLSGVEDVPKVVQEILRSDKGFERSKIDGYLHQLELGLKHKTANFGMSLLHRLWFVGVDPFDIAAFETELAKYLEGLIDKYLINDLSFTMA-PSPTFSQELAQEEETRLSTKISEVVEEARAALEARELKLLAEQSKEDLGCLPSVHVKDIPRQAP-TNGLTYFRAINQLSLIPLFTDSIMRL-GTEQLEDLIKLKTGGVSLMFSGMALDRHVPTMFDLLRKLVVETDFDSPQQIRQLLNDIASSGHAYAAESGLTGLSQVKLVTSLASLEDVIAKLKQIALALPTASYTAAPLQILSQLLTHKHLHHEIREKGGAYGGGSYARGIFGFYSYNTLKIMRNAGQWAKISVFQGVDAAVNEEGMAQFLYGITDEMKQRREELLDVTKDQVREVAQEYVVFLGE Orpsp11 KVKPIKEFDLVALKLNHIKTGAEYVHIAN-DDSNNVFSIAFQTAGKDSTGVTHILEHTSL--CGSKKYPVRDPF--FKMLNRTLATFMNAFTAADCTFYPFSTENEKDYYNLMDVYLDATFNPLLRDFKQEGWRVESP--YQFKGVVYNEMKGSLSDQQMHPGSGGDPEYI-VELTYDELKKFHKKHYHPSNSKIFTYGNFNIHLKFIDNISKYEPRKVHMMCPKMCVSFLLYESFVMQVLSHLLLSGESYPMHKALI-ESNIGSDYSAGTGYDDNARFSVGLQGISDVEMVIMDVFKDKNGFDKKQIEAYLHQTELNLKHKTASFGLNIMESMWIHGADPIDLDRFKKEYTQFFEKRIEKYFLNNLTFIM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 EKKHVPELHLTAVWLKHDQTDADYMHVAR-DDKNNVFGIGFKTNPPDATGVPHILEHTTL--CGSEKFPIRDPF--FKMLPRSLSNFMNAFTASDHTTYPFATTNQQDFQNLLSVYLDATLHPLLKDFRQEGWRLGED--IVFKGVVYNEMKGQISDESIFPSSGGDPEYI-TDLTHKQLSEFSKRNYHPSNSKILTYGDMPLHLKQIGALDSFQPLNVTVPGPKTSTSWYVVETFSVGIVSSLLLDGYGSPMYRALV-ESGLGSSFTPNTGLDPSSRFSVGLNGVAEAPTVIQNVFRESSGFSEEKVRGFLHQLELSLRHKTANFGIGVMEKTWLNGSNPMKIDEFKSRYAKYLESLVEKYLINDMTFTMV-GTPTFNKELDEKELVRKNNKLAQLIEKAVTKLGQEELELLKIQEDADLSCLPSLRVKDISREAP-TNGLTYFQALNDFLLMPLFNDCVMRL-GTEQWEDLIKLKTGGISMQFSGFAIDKNIPEMLEMLSVLVTETDFTSPAMIKELLDAIAGTGHRFAASASLSGLEQLQATANLLRLQELIEKLRLIGQASQTVPFVDAPLSILSQLLTHNYLHPEIREKGGAYGAGASNGGIFTFMSYNSLKVFKNSGIFAKLGIFQGLDASVDDEGARYFMSGVTHEMDQWREQLLDVTAKDVNAVADEFLCVLGE Phybl2 SVKRVPELELTAITLEHEKTGARHLHINR-EDSNNVFAVGFHTPVSDSTGVPHILEHTTL--CGSDHYPVRDPF--FKMLNRSLATFMNAFTASDYTIYPFATTNPVDYANLRNVYMDAVFHPRLTDFKQEGWRLETP--IQFKGVVYNEMKGQYSDQAMFPGSGGDPSDI-TNLSHEELLNFHNQHYHPSNARFYTYGNFPLHLAAVGELKNFEPKKATSTCAKISLSFLTFETFSMRLLGYLLLDGHASPMYKALI-DTNLGTEFSVNTGYDSSTRLSIGLQGVSDVELVIKEVLEQTEGFDPIRIEAAIHQLELGQKHKTADFGLTIMHGIWFNGVDPVDLDALKQGLDKFFESRIEKYLLNNLVFTMK-PDASYATDLVAEEKERLAVKVNSLTESDKTEILEQGKALESAQDKENLSCLPTLTLKDISPKTA-TNGITYFRAISTLMYLPLFCDSLLSL-GTASIDDEIRLFTGGLRLVLSGNCLDRNIDKMYTILTKLVRETNFDNTDKLKTLINSIADSGHVFAAGSTLTGMSQMNFMSQMAALSDVVNKLKTIAKVIRGVPYTHAKLQVLSSLMTNHYLHREIREKNGAYGGGARYAGLFSFYSYATLDSYHNAIDWVKLSIFQGIDSSVSEEGMLQFVNGISDEMRQRREEFLKVTQDDIKAAAETYLAVLGE Picst3 NVQPIPEFSLVAVHLKHERSGAAHLHLDSPTDNNNVFLIAFKTNPPDATGVPHILEHTTL--CGSYKYPVRDPF--FKMTNRSLSNFMNAMTGHDFTFYPFATTNAKDFDNLMDVYLSSVFEPLLSDFIQEGWRLESK--LELKGVVYNEMKGQNSNESIYPSAGGDPAKI-PDLQYEDLVDFHHRNYHPSNARTFTYGNLPLHLKHLSDFQTFGTTVVKVPGPKASITWNQYELFKWKILSSLLCDGHNAPFYQELI-ETEFGDDFSANSGIDATTAFTIGLNNLEKVGQLVLDIIRN-SSY-KTRIEAILHQIELNLKKHKPDFGLSLLNVIWVNGLDPIKLNQFKSDFECVFKELLDSSILNPFSFVME-PQNEFNKNLTTVEAERVKTMVQSLSEEDKKIINERGQELARKQTEQDGEVLPTLTIKDIPEKVD-TNGLVYTAALKNIKYLSLFSSCLTNLAGTTDLETKISRLTGGISFQMSGMALKENSEHIYNLWHEVLTDTQFDSNDKLFTLINVIADRGHSYASNAKLTGISQVEFIMELNSADEILPILKEISLGKLGAEYACASLQILAQLYTFKHLHSVIRESNGAYGGGLLYDGTLNFYSYKSVESFEKSFDFGKLRIFQSVDANIASQGSTEFYEGITDVMRQRRENFLSVNNQDLTNVIQKYLTVIGD Plicr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo NVQDVPERQFNTFRLKHDVTGADYLHIDC-EDKNNVFAVTFKTTPFDSTGVAHILEHTTL--CGSKKYPMRDPF--FNMLKRSLNTYMNAWTAPDHTSYPFGTQHEKDYYNLLSVYLDATFFPLLTDFRQEGHRLESK--LKFKGIVFNEMKGALSDQSLYPGSGGDPKDI-PALSYQQLKDFHATYYHPSNAFFFTYGDLPVHLRYIEELQHFKPRRITVTCPKLSISILIFEGLSMNVLSNLLIRGSNTPMYQALL-ESGLALDYTPNTGFDDNLHFGVGGTGIEDLEKVIISTMEKRDGFDSNVIESILHQYEFGQKDVSASLGLKLVGGLWIHGGNPINIARLRKEIAAFFQNKLRQ-LLDNLTITMS-PDDTQQAREAAEEENVLLGIKSSLDSKQVETIVEQAKDLQQRQSQQDVSSLPKLSISEIEKKFP-TNGITYFRSMIDIMYVPLFCSLFESM-GAKQLDTEINLYTGRMNIYIKSAAINRNIEKMFSLLKKMMLENRWNNPDLLKNLLEGITSSGLSYASSSQFSGLTHVKFTNDIIALNDIIAKLIAISKSYQGVNYSHARLEVLSKVLS-EYLHKEIREKGGAYGGGVSYAGSIGFYSYKTINAFNESIEWSQLSIFADFDASPSNKGVAEWMRGITDEMKQRRDRLLSINKNQLEEVSAKYLTVLGK Pucgr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 QVRKIPELELTAISLKHEATGAQHLHIDR-EDSNNVFAVGFHTPVENNTGVPHILEHTTL--CGSKKYPVRDPF--FKMLNRSLASFMNAFTASDYTIYPFATANKVDYSNLRDVYMDAVFHPKLDDFKQEGWRLETP--IQFKGVVYNEMKGQTSDQAMFPGSGGDPKYI-TDLTHQQLLDFHKKHYHPSNSRFYTYGNFPLHLQAIGELEDFKPKHVDTTCA----------------------HGHASPMYKALI-DSNLGSEFSANTGYDNSTSLSIGLQGVEDVQKVIKSVLKEETGFDSKRIEAAIHQMELSQKHKTADFGLNIMHGIWFNGADPLDLARFKSELARYFEKLIDRYLLNNLSFVMR-PDENYTANLSTEEQTRLQEKVKALTEQDKLDISTDAKDLLISQEKEDISCLPTLQLSDIAPKTS-TNGITYFRAISSILYVPLFCDALLSL-GTAEIDDEIRLYTGGLRIVLVGNCLDRNIEKMYTILSKLIHETNFDNVEKLKTLINSVADSGHIFAAGSSLTGLTQVKFMNQLAAISNVVEKLKEIAKALRGVPYTHASLQVLSSLMTTHYLHKEIREKNGAYGGGARYGGLFSFYSYATLDVFRNSIKWVKLSIFQGVDASVSEEGMLEFVNGISDEMMRRRESLLKVNQEDIKRVAHEYLALLGE Rhoto1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 ASQRYNEYKMTAYLYEHIKTKASYMHLEK-SDTNKLFAVGFKTLPADNKGIPHILEHLTL--CGSEKYPVRDPF--FRMLRRSLSNYMNAWTFPYFTMYPFTTENESDYNNLMRIYVDAVFRPLLKDFMQEGWRLESE--VEFKGVVFNEMKGALSDKAMFEGSGGDPSEI-LRLGYEELVRFRNENYHPTNAYFVSYGDVNVVMEYLDSIKEFENETVYIDCPKMVLSFYLYESFVMRLLSCLLLNGPASPMYKSLI-ETNLGNEYSPINGYDCNTPFSFGLQGIGDVEKVIFETLEKYEGFPMERIEAALHQIELSLKHKTSKFGIGIAQSLWMHGINPLELNKLREELKDMFKSRIFKYFFKDFKIIISKPNKNYQKDLDEKESKILNELIK---KNDKNKILKEALKVKQRQEEEDENILPCLEINEISKKTE-TNGINYFNAIIPFSFIPILSFMLSDL-GVAQFQQDIEQHTGGISLSISSYALANNTNKMFNLISEALKSTNFNDIDHIKTLISSISSQGHSYAAASKLTGLYYVRFLDMLKSIKEISETLHFLSLAIKAVPYLHMALSVLAKLLTNKFLHKEIREKNGAYGGGASYSGIFSFYSYKSIEIFKSTEEFVKLGLFSAMDSDVQSEGVLLFEHGITDEMRQRRNRLFEITLEDVYRVAGNVLVVLGK Sacce1 RILPVPELRLTAVDLVHSQTGAEHLHIDR-DDKNNVFSIAFKTNPPDSTGVPHILEHTTL--CGSVKYPVRDPF--FKMLNKSLANFMNAMTGPDYTFFPFSTTNPQDFANLRGVYLDSTLNPLLKDFDQEGWRLESN--IVFKGVVYNEMKGQISNQSIYPSSGGDPMKI-TDLRYGDLLDFHHKNYHPSNAKTFTYGNLPLTLKQLNEFSGYGDIDVKLLGQKASMTWITYDTFLLKVLGNLLMDGHSSVMYQKLI-ESGIGLEFSVNSGVEPTTALTVGIQGVSDIEIFVNNIFQNEHPFDRKRIDAIIEQLELSKKDQKADFGLQLLYSIWTNKIDPFELQRFRGDLETLFQDLIRKYIVHKFTFSIQ-GSEEFSKSLDDEEQTRLREKITALDEQDKKNIFKRGILLQEKQNEEDLSCLPTLQIKDIPRATD-TNGITYVRGKRLLPYLPLFAESLTNL-GTSEIEDQIKLHTGGISFGFDGWSLNSKTDHIFEFWSKILLETDFHKNSKLKVLISSVADAGHAFASAAHYRGIEQLQFINRLHSQREVVDKLTELSQALLGVPYTHSALQVMSNMLTFKHLHREVREKGGAYGGGASYSGIFSFYSYKSLETFKNSGRYIKLTIFQQVDASPKGEGVTYFMSGVTDDMKQRREQLLDVSLLDVHRVAEKYLTVIGP Salro GVRPVDEYNMCAVHLMHEPTKAEVLHFAR-PDNNNAFAVAFATLPTDDTGAPHILEHTVL--CGSKKYPTRDPF--FKMLNRSLSNFMNALTGPDYTMYPFSTTNAQDFANLMHVYLDAAFFPNLNDFCQEGWRLESP--LQFK--------------AFFPN---------LDFCQEGWRLEHENVHDKSSCVFLTYGDMPLHLDIIERLQHFSPQQHHIHCAKMSVSFLLYESFVYRMLSSLLLDSASSPFYQALI-DSGLAPEYSPNTGLDMHTPFSVGVQGISAVDDVIDATLQRNDPFDDQMVQALLHQIEVRQRAVSANFGLHLVTNVWNHGLDPLDIERFRREYSQLFQKIIRRDFVENLEVVMT-PSKSYQEDLDAKEKEKLNAFVSKLKPADVDAIYDRNLELLASQQKRDVSCLPTLHVEDINRSQP-TNGVCYTRAFFDGLFLPLFNQMLTTA-GVKEFPQKVQNCMDGLSVNVSSLCLSEHAGDAFSLWQRLLVEARLDDHHHLRNIIHDTPGTSHAPATTTTTAGLAQRPRSRRLPQLRAILPRKRPAASQMHEAPFMHAALDVLTGLLIPAHMAEAVKETGAADKNAAALDRILGHSTWKIVDVLDALIDFAKTSILAAIEAKPEQQGCFYFTNETTGEVEKRREQALTISYDDLGMAYRRFRATLGA Schco3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 DTKKVPELQLNYTRLKHEPTNADMIHLDR-EDPNSVFSIGFQTPAENDEGIPHILEHTTL--CGSNKYPVRDPF--FKMLNRSLATFMNAFTASDFTFYPFATVNTTDYKNLRDVYLDATLFPKLRDFLQEGWRFESP--IIFNGVVYNEMKGQVSDQHLFQGSGGDPLAI-PDLKYEELVKFHRSHYHPSNAKILSYGSFPLNLSALSEFRPFSEKRVVEYGPKTSISFLVYETFALKVLSKLCFDGFSSPFYKALI-ESGLGTDFAPNSGYDSTTKFSVGLEGAESLAKIVYSIFNDLKGFENEKLEAILHQMEISLKHKSAHFGIGLAQSLWFNGADPADIEWLKQKNSDLFQKLIKKYILENFVFTML-PSSTFPQRLQEAEAKKLQERTSKLTDEDIAEIEKTSVKLLEAQSTADTSCLPTLSVSDIPETLA-A-GLTYIRLLLPLPYLPVYCDACLNL-GTGDLEHQIRRYTGGISIAISGYALDKNVGKLVELINKAFWNTNLSNTDKLAIMLDGIAEKGHSFASASGLTGLTQVKLLSQLSRFGPLVEKLTAIAKSCLGVPYTHAPLQILSSLLTHKYLHGEIREKGGAYGAGLSYSGVLSFFTYRSLSVFDEASEWAKLAVFQGIDSSESQKGMLYFVDGVTDEMLQRRKQLLNVSANDLKAVAKKYLAVLGP Sorma RSKHVPELELTALHLQHDKTGAEHLHIAR-DDSNNVFSIGFKTNPPDDTGVPHILEHTTL--CGSQKFPIRDPF--FKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDATLHPLLNDFTQEGWRIGRK--LVFKGVVYNEMKGQMSDDHIFPDSGGDPQKI-TDLTYEQLKKFHADHYHPSNSKVFTYGDMPLHLKEIGALDAFDPREVKLYGPKTSVSWVVVESFSLALISALLMDGYGSPLYKGLI-ESGLGTDWSPNTGYDSSGKFSIGLSGVEDVPKVVQEILRSDKGFERSKIDGYLHQLELGLKHKTANFGMSLLHRLWFTGVDPFDIAAFETELAKYLEGLIDKYLVNDLSFTMA-PSPTFSQELAQEEETRLSTKISEVVEKARVALEARELKLLAEQSKEDLSCLPSVHVKDIPRQAP-TNGLTYFRAINQLSLIPLFTDSIMRL-GTEQLEDLIKLNTGGVSLVFSGMALDRHVPTMFDLLRKLVVETDFDSPQQIRQLLNDIASSGHAYAAEAGLTGLSQVKLVTSLASLEDVIAKLKQIALAIPTVSYTSAPLQILSQLLTHKHLHHEIREKGGAYGGGSYARGIFGFYSYNTLKIMQNAGQWAKISVFQGVDAAVNEEGMAQFLYGITDEMKQRREELLDVTKDQVREVAQKYVVFLGE Sphar GIESIPELSLTAVQHVHDKTGAVGLHIAR-ADDNNVFSIGFRTPPEDSSGVTHVLEHVSL--CGSEKYPCRDPF--FKMLSRSMATYMNAWTASDYTMYPFSTQNANDYNNLLDVYLDAVLHPSIRDFLQEGWRLETD--LQFKGVVFNEMKGALSDQALFPGSGGDPPSILSKLDVNVLREFHRTHYHPSNARVYTYGDLPLHFESIGPFDSFDPCEVIAHCPKASIGWLAYEGFCQRILTSLLVDGSSSPMYIALI-ESQLGSDYTPNTGLDTSTRFSVGLQGISDIPMVIEKTIQKEDGFEAERVEAVLHQIELSQRDQTTSFGLGLAAALWVNDCDPVEVERFRTDM-AFVKNFFERHLISNLTFIMT-PDEKFTNNLAQQEADYLKEVVSTLSDESRDRVYEQGLQLLKEQETPDLSCLPTLRVEDIERKQP-TNQMTYMRTIFNTPYIPLFCSVLPSL-GARELGQKTKLWTGGIRIMLLARCLDRNLEHTTSLCSDILNESHFDGTERLYTLVNSVSDAGHHFAAAASLTGLTQIDFMRKLAEQQEILSKLRELAKSVASIPSNHATLQVLTSLLSAKFLHREVREKNGAYGGGLSAGGSLSYYSYATLKAYNEAPQYLKLTVFQRMDKSPGSKGMSGFVYGVSNEARQHRDRLFAVDREALVQATNKYLVIIGP Spipu1 NVRKVPEFDLTAIQLKHEKTGAGYLHVFK-DDSNNVFNVGFHTPVNDSTGVPHILEHTTL--CGSKRFPVRDPF--FKMLNRSMATFMNALTGNDYTMYPFSTENPVDFRNLMDVYMDSTFAPLLRDFKQEGWRLETP--IIFKGVVYNEMKGVLSDQHFYPGSGGDPMAI-TDLTHSQLVEFHKTHYHPSNARFFTYGTFPLHLKAIDDIARFAPKRIRVTCPKMAVAFLVFESFAMRVLTSLLMDGAASPMFKALI-EPNIGSDYSVTTGYNQHTKVSFGLQGIEDVDMVIMDVLRDRTGFDPERVESIIHQTELGLKHRNANFGMMVGQQVWVHGGDPLEIQQLRASLAKFFESMIEKYFLNNMVFIME-PDERFSEELAETERKKLDKMVNNLSPTEKQKILEDGVKLTRSQEAEDVSSLPTLTIADIAQETA-TNGVSYVSIVKAIEYLPLFSSSLPSI-GTPVLDEAVRMFTGGISLTLSSSCLDKNISPMYELMSEIASEAAWEDLERLRTVVQGVVQSGHRYAAGAEVTGLTQVGFLGRLARIQQISEKLQEIAKSYLGVPYTHAALQVLASLMTHRFLHREIREKGGAYGGGASYSGTLSFWSYRTLQAYDRAVEWAKLSIFQNVDASAAGEGMLRFRTGITFEMQQRRERLFAVTLSDVKDAAAKYLAVLGG Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 RTKSVPELQLEATLLKHDKTGLEHLHIAR-DDPNNVFSIGFATPPTDSTGVPHILEHTTL--CGSEKYPVRDPF--FKMLNRSLATYMNAFTASDYTFYPFATVNQADHANLRDVYLDATLFPRLRDFLQEGWRLETE--IEYKGVVYNEMKGQMSDREMYRGSGGDPKNI-PDLSYAQLLAFHQRHYHPSNSKVFTYGSFPLQLESLNALMAFSYRQVEVEGPKTSVSFLTFETFSLRILSSLLLDGHSAPLYKGLI-ESELGSDFSPNTGYDNSTKMSVGLQGVQNLNKIIQEILQGNDGFAQDKVDGILHQMEIALKRKSANFGMSLLNSVWFNDVDPLAVDRFKQNLASYMGDLIRKYLLKDLGFTMR-PSSDFASQLAKAETEKLNSAVSSLTEGERVKVQENGLALLKFQNAENLDCLPTLRVSDIPKTKA-T-GITYFRMIAKLPYLPLFTDCFTNL-GTATLEDAIRLKTGGISIAVTGHCLDQNLSSMFHLIRTIITETDFDNTDKLRQLLSNVAESGHSYAAASLLTGLSQVKLVSALANLSIIISKLKRIALSMRGVPYTHAALQVLAKLLTNKHLHREIREKGGAYGGGATFSGIFGYYSYKTLQTMEDAGAWAKLSIFQGVDASVASEGMVYFTERITAEMRQRREQLLAVNSSQIREVAEKYLAILGE Thetr ---------------------------------------------------------MVL--CSSAKYAARDVF--FNLSQRTLATFLNAMTAADSTIYPFSTVHAQDFANILDVYCDAVFFPNLTDFDREGWRLESPGGVRYHGIVFNEMKGVVTDKALRAGSGGDPLAI-PSLTHDELRAAHAKYYSPANALFFSYGDLPLHIEYLEDLSRVPAERAVIAGPYHGSEWLPAANLNLQLLSSLLLNGAASPVYKAVI-ETGLAADYSQRTGQNTEMALGITFQGIGATDRIVAAALDSADGFDPARIDALLHQIEISLKARPDNYGLALSSSLTSLGASLPDLDEFKADPQGTLDALLAS-----VTLTME-PEPEFLASRDAAEAAALEVAGAELSAGAKAELEAVTKTFYARE--EDVSALPAISIDECSEEAP-TNGLVYVRALTRVALLPLYASLLPSL-GTATIDQELQMKAGSLSVSVSGSFLEAKSADALNLFAEILTAPDWTDTERIGTLVSSIQFSGHSFAARSRLNGLSQLNVLVPLANLASVMDALGGLASAIPTVPALHTPLSLLGSILSSEYLLPVVRQKGGAYGAGASQSGAFTFFSYATLDAFAGSEAFCKLRGVARLDAAPSQFGAAYFNAGVEDDVRQLRSALFAASVDDLRRVAAEHLTIIGP Treme1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 RAKHVPELELTALQLQHDKTGADYLHIAR-DDTNNVFSIGFKTNPPDDTGVPHILEHTTL--CGSEKYPIRDPF--FKMLPRTLSNFMNAMTASDHTFYPFATTNEQDFKNLMSVYLDATLHPLLKDFLQEGWRIGKK--LVFKGVVYNEMKGQMSDDHIFPDSGGDPQKI-TDLTYEQLKNFHAENYHPSNAKLFTYGDMPLHLREVDALQAFEPQEVTLYGPKTSVSWIVVESFSVSLLSTLLMDGYGSPLYRGLI-EAGMGADWSPNAGYDSYAKFSIGLTGVSDVPKVIQEILREDKGFDQGKIDGTLHQLELSLKHKTANFGYSMLNRLWFNGTDPFDIAAFQAKMAEYLEGLMDKYLLNDLTFTMA-PSATFGDDLIAEEQARLSSKIQDAVETARLQFEKQEQDLLVEQNKEDLSCLPTVHVKDIPRSAP-TNGLTYFRAINTLELIPLFTDSIMRL-GTEQLEDLIKLKTGGVSIIFTGMALDRNVPVMYDILRKLVQETDFDSPERIRQLLNDIASSGHRFAAESSLTGLSQVKLVTSLTSLEDVIGKLKKIGLSVSTTSYTSAPLQILAQLLTHKHLHHEIREKGGAYGGGAYSKGLFGFYSYNTLSIMRNAGRWAKISVFQGVDASVNQEGMARFLSGITEEMKQKREQLLDVTKDQVRDVAQKYLTFLGE Umbra1 ETRTVPELQLTAIQLQHEKTGAKHLHVDR-DDSNNVFAVGFSTPVSDSTGVPHILEHTTL--CGSQKYPVRDPF--FKMLNRSLATFMNAFTASDYTIYPFASANEVDFNNLRSVYMDAAFFPHLRDFKQEGWRLESP--IVFKGVVYNEMKGQMSDQEMFPGSGGDPKNI-TDLTHEGLVQFQKTFYHPSNSHFYTYGNLPLHLEAIDAIRNFDPREIVLPCAKLSLSYLVFETFAMRLMSYLMLDGHASPMYKALI-ESGLGAEFSANTGYDSSTMFSVGLQGISDIDTIIQEVFEKQEGFDHNRVEAALHQMELSRKHKTADFGLSIMHGVWFNGTNPADIDRLRKELAQFFESRIEKYLLNNLTFVME-PSTTFAAELSKEEQERLESKVSALTESDKKEIEERGLELLANQDKEDLSCLPTLTLNDIPLKAA-TNGITYFRAISTSVYLPLFCDALTSL-GTAIIDEEIRLFTGGLNIALTGNCLDRNIDKMFDILETLVHETNFDDAQKLRTLINQVASSGHAYAASSTLTGMTQVDFMNKLASLSDVISKLKLIAKVLRGVPYTHAKLQVVSSLMTSHFLHREIREKNGAYGGGAQYAGLFSFYSYETIDTYSKAVDWIKLSIFQGVDASVSQEGLLQFTDGISDDIRQRREQLLNVTEEDVKHAAHQYLAILGE Ustma22 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 RVLPVPELKLTAVDLVHERTGAEHLHIDR-DDKNNVFTIGFKTNPPNATGVPHILEHTTL--CGSVKYPVRDPF--FKMLNRSLSNFMNAMTGPDYTFYPFSTTNRADFANLRDVYVDATFNPLLTDFYQEGWRLESD--IVFKGVVYNEMKGQVSNESIYPSSGGDPQKI-TDLFYQDLVDFHHAHYHPSNAKTLTYGNFPLSLQRLNEFENFGDLEVRKAGQKTSMTWITYETFLLRVLSNLLMDGHSSVFYQRLI-ESGIGLDFSVNSGLDSASAVTIGLQGVQDVDEFVKDIFAENKPFNRDRIEAIMQQLELSKKDHKSDFGLQLACSLWTNKVDPFELQRFREDLENLFQDLLKKYIVDKFLFTME-PVEDFSQRLEVEEKERLGRKLDQLDESDREVVYNRGLLLQEKQNAEDLSCLPSVKVSDIPRKTD-TNGISYIRAKRELPYLPLFADSLTSL-GTSDIEDAMKLHTGGISFRVSGWSLNSKTEHVFDLWKKLLLGTDFQKHSKLKILISAVAEAGHSFAAAASFSGVEQLQLINRLNSQREVVDKLVELARSLPGVSYTHAPLQVLANLLTFKHLHTEVREKGGAYGGGASYSGMLNFFSYQSLKTFENAGQHAKLTIFQRLDASRKSEGVSLFYSGVTDEMRQRREQLLDVTRKDVDRVAEKYLAVVGP [Cluster3236.fasta_al_trimmed; alignment length = 135] Allma1 LARGHLDNQREAVIKQSREITRESKKLIVMLQAKVLQM-LSKLAAQFKSRYSSNVKHCIQEFLEAVAFHYFLRRMIPFDDARLLLLMPQDYIMGISDVSGEVMRFATNAATIDTTRESVLKVERLAYDLAIRQSE Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 TFRDELDDRRERVIKTSRDITALSKKI-----DQISTL-FQNVIPDVTGRYQRQLSGAIQEFIEALSFNHYLQSLISHAEVSKHLVTEEDYLLGMFDLTGEMMRFAITSLSVEVMQNSVEKVERAAYGILVRGSE Aurde31 KFRDELDEKRERLIKTSREVTTNAKKIIFLLHHEINAL-FARMAPDLAGRHWRCVSPGLQEYIEALSFAHYLGTLASYHDVQAAILPLSDYLLGISDLTGELMRFAIVAITQDVTAASLQKIEDAVYAVVVRGAE Batde5 --------------------------------------------------------------------------------------------------------------------------------------- Botbo1 DFRVQIDDRRERLIKISRDITIHSKRLIFLLHKPIRAF-FEAASDELRGRYSQSLSPGVQEYIEAISFSHYLGTLITHAQAQALILTHSDYLLGISDLTGELMRLAITSSGQSVTTESLKKIELAAYGIAIRGSE Botci1 --------------------------------------------------------------------------------------------------------------------------------------- Caeel --------------------------------------------------------------------------------------------------------------------------------------- Canalb1 PARDNLRDDREGVIRLCRDITSYSKKGIFSLHKELAGY-FNVLSDRLAK-LRGTISGAVEELIEFFTFAFYKFQLLRYDVFLKMIIDLADYLMGIFDCTGEIMRMCISQSSLQVFESSLKKIESTLLDILVSDKE Cangl --------------------------------------------------------------------------------------------------------------------------------------- Capow QFAATMDDRHERLVKLSRDLTVQSKRVIFAAQEDIRQNQIRPMAVELVD-YARAYSPGMQEYIEAVSFVHYLATLITQRQLEEQLVTITDYLLGVTDLTGELMRFAIASVGLRVMQSSLEKIEQVCYNITVRGSE Catan2 EAKAHLDERREALIKKSREITRESKKTIVSLQNKVQKM-FTEISSVLHSKFARDIRPGIQEFLESASFLHYFGTLLSFEQAADLMLTPEDYLFGVLDLGGELMRYATTSATREVLEQSVFKVEQLCYHLTV---- Cioin --------------------------------------------------------------------------------------------------------------------------------------- CocheC53 GFRAELDDRRERIIKASRDITASSKKILHVIQETIQDR-YKSIAADLQGRYSHNITGGNQEFMEALSFQHYLQSLISYDEAKSRIFTPEDYILGVCDMTGELMRFAVTSMAMPVMRECVDKVEKGLYGLTVRGNE Coere1 KYRDTLDDQRERIIKCTRDITALSKKIVFALLAQVLEL-FRKLSKELQGRYNRQATAGIQEYIEAIGLWHFLNNLITMDQVLERLVTNEDYLLGISDLPGEVNRYCINAIGLPVLNSSLEKIEKTYYSMAIRENE Conco1 --------------------------------------------------------------------------------------------------------------------------------------- Conpu1 GFRQELDDRRERLIKSSRDITNLSKKVIFLLHREIQEI-FFRLKGEIQGHHRRSVSPGLQEYIEALSFAHYLGTLITFAGVQATLLPKEDYLL------------------QHVTAQSLEKIESAVYSIVVRGSE Copci AFREELDDRRERLIKASRDITNLSKKTIFLLHRQVQDL-YASLRPELVGRHERQVSPGLQEYIEALGFAYYLGTLIPFNEVQKTLLTVSDYLLGLSDLTGELMRYAISGLSQAVTSNSLEKIEDAVYAIFLRSSE Croqu1 SLASEIDDRRECIIKLSRDITSASKKVIFHLHAEVAKS-LWAVSKQLDSRYYRSISPGIQEFIEAKTYCEYLQRLVTRNEIEDYIITIEDYAGGVADLTGELMRHAINSVGMTTMQSSLKKIENAAYTIKVRGAE CryneH991 AYRAELDALREKLIILSRSITQLSKKLIFHLHREIAEV-FKTIRQELSDKWRKSITPGLEEYIEALSFMWYLGGLVPLDNVQKALVTPEDYILGMSDLTGELMRYATNALGQEETQRSLEKIEK----------- Crypa2 HFRDELDDRRERIIKASRDITALSKKMIFSLQTDISRL-LSSITLEVQGRYSRQMS-CIEELIEALTFAHYLQALMGYEDAAARV----DYLMGIFDLSGEMMRYATVVAALETLRQSVFKVERLGYGLKVRGSE Debha1 PAREYLLDERELVIRLCRDINSYSKKMIFTLHEQLLAN-LKIISEKLSIQLKSTVSNSVEEMIEAFTFAYYIRDVLPYDKFSYVIILPGDYLMGLFDLTGEIMRYSITHIVLLTLQQSISKVETMICDMSIKGNE Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------- Dicdi SFSKKLDDRRERIVKNSRDITIASKRVISLLQQPIFNL-FGNIIKELDQKFQKAFTNGVQEYIEAVSFQYYIGALIPLDSILIPIISIDDYALGICDLSGELMRYSTGCVTMNTMEESLKKIEKLCFSIRIRKSE Dmel IYSNELIDRHERIVKLSRDITIESKRIIFLLHNKLIAVNFRAVALELRDQFRSSYSPGLQEFIEAYTYMEYLKSVSDWQAIQAVMVDPTEYILGLSDLTGELMRRCINSLGITTMKQSVLKAENVCYNVKVRGGE Enthi --------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LMRDELDDRRERLVKTSRDITIIAKRVIFLLHVAAQKL-FRSMREDLEGHYQQAISPGLQEYIEALAFAHYVGRLIGYHDVQNSLLPMDDYLLGVSDVTGELMRFAITAIGQSVTAQSLQKIEDTAYAIAVRTSE Fusgr1 GFRNELDDRRERIVKASRDVTAMSKKIIFTLQEEIAKI-LSAIAPDLQNRYTSPLR-CLEEFVEALSFAHYLQTIITPTQAQAAMLTPHDYMYGIFDLFGELMRFATVTTAMGAMRQSVKKVEKLGYGLVVRGSE Galma1 EFRADIDDRRERLIKASRDITNLSKKTIFLLHREIQGL-YAKLQPELQGKFQRQVSPGLQEYIEALSFAHYLGSLITFDQVQRTLLPVSDYLLGLSDLTGELMRFAISGIAQSVTTQSLEKIEDAAYAIMVRSSE Ganpr1 --------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ------------------DITGLSKKLIFLAHKEILEL-FQKVSCELEGKYHKSISPAIQEFIEAISFLEYLNRLISMNDVELNFVTVEDYVLGIADLTGELMRYAINSVGLDGIKTNLAKVED----------- Hisca1 TFRSELDDRRERVIKASRDITALSKKIIFSLHTQITTL-FKSVVPDLGGRYQWQISPGIQEYIEAVTFQHYIQRLMSLEEVARSLVTEADYILGIFDLTGEMMRFAIMIMTLEVMQNSVEKVERAAYGLLVRGSE Klula1 --------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 NFRADLDDRRERLIKASRDVTNLSKKTIFLLHVEVQTI-YAGLKQELEGRYQSQVSPGLQEYIEALGFAHYLGSLITFDQVQRTLLTISDYLLGLSDLTGELMRYAISGISQYVTAQSLEKIEDAAYAIFVRSSE Lenti61 QFREELDDRRERLIKSSRDVTNLSKKVIFLLHREIQSL-FAAMCPELAGRYQRNVSPGLQEYIEALSFAHYLKSLISYDQVQQSLLPLEDYLLGLSDLTGELMRFAIASISQHVTAQSLEKIEDAAYAVAVRTSE Malgl1 QFRDEIDDRRDRLIKTSRDITSLSKKVIFHLHHEIYDV-IRTCKEELASRYERCIGMSLEELVEAASFLHFLNSLIHHEDIQQHLVSPMRYLLGLCDLNGELMRLAINAAAMSILTHATDTLQ------------ Mellp23 SFANELDDRREAIIKLSRDITSASKKVIFYLHAEVVKT-IWMVSSKLSSRYYRSISPGIQEFIEAKTYCEYLRTLITKDEIEEYLITIEDYLGGVADLTGELMRHAINSLGMSTMRSSLKKIEDAAYTIKIRGAE Mnele --------------------------------------------------------------------------------------------------------------------------------------- Monbr GYAKRLTDRYERLVKLSRDVTIHSKRAIFILHVEIREN-LRAIARELQGLYARAFSPGLQEYIEAATFLAFNGRLATLAELEEAIIPPLDYILGIADLTGELMRMCINNL-IDVLESSLKKIENACYTLTVRGTE Morel2 YFRDILEDRRERIIKVSRDINNFSKKMIFALHATVLKL-FHRVAIELRGRYQRSISGAFQEYIEAMTLEYYLGKLMPKSALEADLVTDEDYLLGIADLTGELMRLAINTLGMGVLKQSLQKIELACYNVKVRGAE Mucci2 ---------------------------MLKLNREIIDL-FKKLAVDVQGRYSRSFSGGFEEFIEAIAFYHFLKTVITKEQVDSHFVKTEDYILGLADFTGELMRYAIHVVSLGALKGSIKKVEQACYTFQIRGSE Mydma WVRDRLDDKREKILKFSRDITNESKKVIFSLLQFLKKL-LSYISEELKEMFHKSFSFGVQEFIEAVSLYFFIETLIEFDNVCNQYLFPQDYLGGIADLTGELMRVAVNSLGVCVMKSSLIKIENTIYILKVRGAE Neucr2 QLRDELDDRRDRLGKVSRDITGLSKKIIFALQAEISKL-LATMAPDVQGRYSRSLM-CLEELAEALTFAHYLQTLLKPDELSAFVTTEDDYFYGVFDLSGEMMRFATTSTALDVMRQSVRKVERLGYDRMIRGSE Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------- Pench1 NFRDELDDRRERIIKKSRDITALSKKIIFALQDQIHAL-FEEVVPEQLGRYQRQISGGIQEFIEALSFDHYLQTLITHAECSARVVSEEDYLMGLYDLTGEMMRFAVLSLSLDVMQNSVEKVERAAYGMVVRGSE Phybl2 --------------------------------------------------------------------------------------------------------------------------------------- Picst3 SARASLLDEREIVIRNCRDITAYSKKIIFSGQKEIKTN-FSIIALRLAQSLRGTIASACEELIEALTFIYYVKKLLSYEKMVEIIIDRPDYFMGLFDLTGEIMRFTITNLQLEVFKQSLLKVEKSLFQVLVRGKE Plicr1 GFRQELDDRRERLIKTSRDITNISKKTIFFLHREVQTF-YSEMKEELQGRHHRQVSPGLQEYIEALSFAYYLGSLVPFNYVQSTVLTMDDYLLGLSDLTGELMRFAITGIAQAVTGQSLEKIEDTAYAIVVRGYE Polpo --------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------- Punst1 ALRDELDDRRERIIKASRDITNASKRTIFLLHADIQRL-FAGLREDLQNRYKQNISGGLQEYIEALSLAHYFGNLIPYETVQKTLLPVDDYLLGISDLTGELMRYAVSAISQRVTASSLQKIEDAAYAITVRTAE Rhior3 ------------------------------------------------------------------------------------------------------MRYAIQIVSMGALKASIKKVEQACYTFQIRGSE Rhoto1 GFRTELDAQRERIVKLSRDVTALSKQLIFALHADLRVL-FEKLQGEVQGRYQRSVSPGIQEYLEGFTFYYYLHSLPTLEEAQASLVTIDDYLGGVADLTGELMRLAIASVGLQVLDQSLGKIENASYNLRIRGAE Rozal11 --------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------- Salro EYAKILTDQRERLVKLSRDVTIASKRVIFLLQASIHAT-IRAIAKELDG-HHRAYSPGMQEYIEAITFMAYIGSLPSPEDI-AALIVSTDYILGIADLTGELMRLCINN--MEVMGNSLRKVEKRTHT------- Schco3 GFRQHLDDRRERLIKSSRDATNLSKKVIFLLHKEVQQI-YAGMKGELEGRYQHQVSPGLQEYIEALSYAHYLETLISFEEVQRSLLTTSDYLLGISDLTGELMRFAISSISQAVTSQSLQKIEDAAYTIAVRFSE Schpo1 SFKNFLQDKREKIIRLSREITIQSKRMIFLLHKKIHKE-LESLKRELAGKFSSACTHGLQEYVEAVTFKFWLGTLLSCKDSSFRIINFIDYVLGVCDMTGEIMRFLVTNGSLSVMENSISKVEGICYSKILREAD Sorma QLRDELDDRRDRLGKVSRDVTGLSKKI-----AEISKL-LAVMVPDVQGRYSRSLM-CLEELAEALTFAHYLQTLLKPEELSAFVTTEDDYFYGVFDLSGEMMRFATTSTALDVMRQSVRKVERLGYDRKIRGSE Sphar ---------------------------------------------------------------SAA-----------------------DYLLGVADLSGELMRLCINYLGINVMKQSLTKVENACYAVAIRGAE Spipu1 ELSGVLDDRRERIIKLSRDITICSKRMIFLLHKEIIRL-FDQVAAELKGRHHRSIGPGCEEFIEAASFLVYVGELATKDELQKLLIADEDYILGLADLTGELMRYCINSVVMSTMRSSLWKVENACYAYKVRGAE Sporo1 SFRTELDAQRERIVKTSRDITALSKQMIFALHTELRKL-LAKLQSEVKGRYERSISPGLQEYLEGYTFYHYLRTLPSLSE-----VTPEDYLGGVADLTGELMRLAIASVG------------------------ Stehi1 SFRQELDDRRERLIKASRDVTNASKKVIFLLHKDIRLM-FKAMKPELHGRYQHQVSPGLQEYIEALSFAHYLGTLITFDDVQQTL----------------------------VSAEPGTSIN------------ Tapde11 KFKNDIDDRRERLIKTSRDVTALSKKMIFSLLSQIAQL-LQTAQQDLQERYQRNISPGIQEFVEAITLKFYIQRVPALAETQ-KLLTPADYILGVADLTGELTRRAIAALAIAVMESSLKKVERGVFERCVRGSE Thetr --------------------------------------------------------------------------------------------------------------------------------------- Treme1 AYRAEIDERRERLIILSRSITQLSKKLIFHLHREIREQ-FRKVNEVLR-RWHRQVSPGLEEYIESLSFLHYLKGLITLSDVQAALVTPEDYVLGISDLTGELMRYATNALSQKETTRSLEKIERVCYALRLRLLE Trire2 NIRDELDDRRERVIKASRDVTAQSKKIIFTLQKEIAKL-LSPIVADVQSRYGYSLR-CLEELVEALSFAHYLQKVITPEETQAATLTPHDYMFGLFDLFGELMRFATVTTAMEVMRQSINKVEKLGYGLVVRGSE Umbra1 --------------------------------------------------------------------------------------------------------------------------------------- Ustma22 SFRDEIDDCRERLIKSSRDVTAMSKKVIFLLHQEIISL-LRQAKPDVSTRYERNIGAGLEEFIEAISFYHYLQRLITLRQIQDRFIPAHRYLLGLSDLTGELMRFATNAVGQTVTNQSLQKIEDILYAITVRSAE Walse1 EIKAKVDDKRERLIKSSRDITALSKRMIFSLHKQIQDIWFNRVQDELTRNFSKFVSAGLEEYIEALSFMEFLDMLITIDKVQNVLVQPSEYLGGIGDLTGELMRMAIQILGINTLENSLKKIEDTRYTYEVRKAE Zygro1 --------------------------------------------------------------------------------------------------------------------------------------- [Cluster3238.fasta_al_trimmed; alignment length = 233] Allma1 IVGRDAQRDQITAFL-AALYIAGSPGTGKTALTSEILAWQINVNCMALATPTNIYVAIILLLDELDGLIT-VLYTLFELTHLLLVGIANSIDLTDRLLPLLAT--HPEIVTFPAYSATDLVAIVRARFVGQMQEPAMA-FLARKIAAASSDVRKAITIARTAVRLAVTEAKPHVV-RAFQVASAGGGSALN--FTAKLAILFETY----------------------VIRQLL Ashgo11 LPTREAQYREISAFLGNSLYITGPPGTGKTAQLELAVRAMVSLNCIALRRPESLWSKIVVILDEMDKLLTKIIVDLFLLARFTLVGIANSLDMKDRFLNRLLL--SPKVINFAPYTSEEMFEIVTSKLKSVIIQPMAIKFAAKKCSSNTGDLRKLFDVLRNSIELAELESLR-VTLHVSKVFSYMNSSSLN--LQQKIVLAYDYYLNPLNRNEFLESC-DTLEMYGVLLKKLI Aspfu1 LVGRDAEREKLTSFIGGCLYVSGPPGTGKSAMVREVCNQVAHINCASMRGPRDVYSKLLVTLDEIDHLLTGVLQSLFEWSRLILIGIANALDLTDRSLPQLKA--KPCLLPFLPYNATQIANIITNRLRSLFVQPAAIQLCAKKVASQTGDLRKAFELVKCAIDLIEQETLPRASIHIARITSAFGQGTLN--LQQKAALIFDTYLHPLTATEFKDVI-SNLETLGLILRRLL Aurde31 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 LVGRERERNIVQQFLSGSLYISGLPGTGKTALLEECIRKIVKVNCMSISEPKGIYTSILLILDEIDQLAVDILYQLFTWARLSLIGISNTVDLTYRLLPRLRT--KPQLLNFDPYKVSEITEIIRNRLDMVLMQPMAIELAARKI-AETGDIRKALDVCRTAIELAETEEKPKVTVHILSATTLFGSPNLS--MQLKLLLVLETYVNPLKRTEFMDLL-TNLEAQGLILTTVL Botbo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 LVGRETEKGELNTFVGGCIYVSGPPGTGKSAMINEVTTHKTYVNCMSMKTSKDLYGILLITLDEIDHILTEILYKLFEWSRLILIGIANALDLTDRFLPRLKA--RPQLLPFLPYTALQIKNVIMTRLKSLFLHPAAIELCSRKVASQTGDLRKAFDICRRAIDLIETETKPRASIHVNKITATFGNGSLN--LQQKAALLYNTYLHPLTSTEFRDVV-GSLETLSLILKSIL Caeel LKGRREEFDSLKLWISLSIYVSGQPGTGKTATTMRVLKRSCIVNCASTNTKSALFKTIVLVLDEIDHLANAALYAAFQWPKIIILGIANSIDLTERLLPKLML---PKRLVFEPYTKDDIVEILNDKMKNESIDAKAIELTARKVAAMSGDLRTALHIF--------KQQK--------RMIPVPGTPV---------EVLQPR-LSANKK----------------AFQTLE Canalb1 LTSREKEAKYITDFVSNSLYISGPPGTGKTAQVQLILQRVVKINCMTLNNPEQIYHEIIVLLDELDSLITQVLFQLFKMAKLVLIGISNTLDLNSKFLPRLVR--NLDNLQFLPYNADQIKSIIMNRLSNLIFHPGAIQFCCKKSASISGDLRKAFDICYKSIELVERS---KVMIHVAKICMSFGNNELN--LLQKAILFYDYYIGSLKHTEFIEIL-YALESSSCILKKIL Cangl LVSRRTQFDQVIQFLSDSLYITGPPGTGKTAQLNSILKAIISINCITVNDPSSIFNKIIVILDEMDKLVHKVIFELFLLAKLLLIGIANSLDLKDRFLSRLNL--KPETVVFQPYTADQMYEIINHRINSVLFNPMAIRFAAKKCSGNTGDLRKLLDILRNSVEVMELERIMKVGLHIAKVFTINNTQSLN--MQQRIVLAYDYYFVALKRNEFLEIC-NALEMMGVILKELL Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 IVARDTESTVIRSFLSSSLYICGSPGVGKTALVTQLVSTVIHVNCFSLRPPEAVYAKIILVLDELDALYPAVLYSLFSLTHLALIGIANALDLTARLLPHL-----PLTLTFHSYSVPSLVQVLQSRFGKDKLKPAAAMFIARAVAKDSSDVRKALAIARD----ACARARVHEVIKAASVSAAATSSVKP--AHAKLALLYNTYLKPVHEAEFGDLV-AVLEHDRLYLREVL Cioin LIGRESELKEIEDFISGSLYISGAPGTGKSACLSQALSQSISINCMSVRTASQIYQQILLLLDEMDQLDSEVLYTMFGWSKVILIGIANSLDLTDRILPRLQA--RPKLLNFKPYSKDQLANILQARISKAVVDAMAVQFCARKIAATSGDARKALDVCRRAVELVE----TKVGIQISSVMDVY----FP--LQQKLVVLRETYVSAVSQSEFHSLC-DLVEARGLLLSSIL CocheC53 LFGRENEKKELQTFISGCIYVSGPPGTGKSAFVSDVCRQTGYINCMSVKNARDLYRTLVVTLDEVDHLLEDLFYNIFEWSSLILVGIANALDLTDRFLPRLKA--RPQLLPFLPYNAAQISSVITSKLKALFLHPTAIMFLSKKVAAQSGDLRKAFDICRRAIDLIEADTRPRATIHMAKITAVFSNGTLN--LQQKAVLLFEAYLHPLSSTEFRDIV-ASLESLSLILRGIL Coere1 IIGRESEQMTIRKFLGGSMYISGNPGTGKTACLQALIK--VLVNCVPLTRPGQVYAAVLVILDEVDSLLGEVLYRLFELARLALVGIANALDLTDRFLPRLQA--RPLLLNFNPYQVNDIVVILQSRLDSVLIQKAALELCARKVAATSGDLRKALDVCRQAMEAAEAEHKPKVTIHIAKVLTLNGSSTLN--FQQKLVLLFAEYLAPVTRSEFFDLV-AMMETQGV------ Conco1 LVGRTSEREQINSFFTSTLYISGNPGTGKTALIQEFITTIYYFNCTGLKTNREIYSKLLIILDEIDQLLGEELHQLIEWTTLSLIGISNTLNLLEKFLPKLKA--KPLSINFLPYKVNELTDILKFKCKDLLVNAKAIEFCSRKVASDTGDLRRALDLLVQVVDYTQEQ--IQVGIQALSVTKLNQNGLVN--ISQKLILIYDKYFHPISTTEFRDCL-TNLEVLGAELEGLL Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 IVGRSQEVIKLTHFIGKSLYISGPPGTGKTHLIHSVLLKVHLINCIAIGGSDELWRQIIIVLDEIDHLASPLITSLLNLSNFTIIGIANTLDLTTRLISTNVT--TPELIHFSAFNATELVEIVKQRLGHLLFHPTALTLCAKKVSTITGDLRIFLSILRKLIDNLESNVLPKITAEVLKHFK-GSENELN--LQQSLTLSYEIYGGKLSESEWSEVIESSLVSKGLILNQVI CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 LIGRDDERHRLRDFLHGCLYVSGPPGTGKSAMVNEITNRKAYINCMSIKSSRDLYITLVVVLDEIDHILSESLYRVVEWSRLLLVGIANALDLTDRFLPRLKS--RPELLPFLPYSAAQVKAIITKRLKSLFFHPAAIELCSRKVSSQTGDLRKAFEICRRALDLVENETRPRVSIHLNKITSAFSNGTLN--LQQKAALLFDTYLHPLSSSEFREVV-GSLETLSLILRSIL Debha1 LTTRDEEAELLNRFLSDSLYISGPPGTGKTAQIEISLNRLVKMNCMSISKPENVFHEIILLLDEMDYLITQVLFQLFNFAKLVLIGISNALDLTDKFLPRLKR--NPQSLQFMPYTSDQIKTIIITKLKSLIIHPAAIQLCCKKSASVTGDLRKAFDICYKSIEMVEHN-VPKVLIHIAKICESYKDNSLN--LLQKAVLFYDFYLGRLKKGEFLEII-GALEAGSVVLKKVL Dekbr2 LPGRQREAKALEKFISTSMYISGPPGTGKTAQVNAILQRLIKINCMTLRTPEDIFKKMILILDEMDSVINQTLFELFSWARLVLIGIANALDLTDRFLPRLRS--NPKLVQFLPYTASQIREIITTKLYNLIIHPSAILFCAKKAAVSTGDLRKAFDIIHRSIEVTEEMTMPKVMIQVAKVCTAFNTDYLN--FQSKTLLFFEFYISTLRRGEFLEIL-STLESNSLLLMKLM Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel LPGRESQLQELREFFSGSLYVSGQPGTGKTACLSLLLRQRVYINCTSIASVGAVYKKLLLVLDEIDQLCTEVLYTIFEWPRILLVGIANSLDLTDRALMRLNA--RPRLMHFPPYSKQQIVEIFKSRLAEAVFPPVTLQLLAAKVSAISGDVRRALDIGRRVVEIAEQQKRKPVQVQVAAVLNVYGAS-FP--LQQKLMLLHEVYILALDQAEFTGTV-DLVETRGILIASIL Enthi IVGREKEYEELKTCIFGLILIHGGSGVGKTTVVKEVLKRTVFINVLLCTNKKCFIRSLILVFDEIDNLKNWLLQALFGIKRCVVIGLANE---TQDYYSMANDFARTAQLLYTTNSLEQICEIIRTKTNN-TFDSKAVEYIAKEVYRKEGDLRKVYSACTLAIHLAIQDNSPVVKMHAIKANGNNGDTS----KYQKCLCWYEKFIDSIKIKEFRNEV-SILASQGVVLKPII Falba IPGRRAELDTLVGLVSGRVYVSGRPGTGKSAMVSALVSRIVKVNCVRVTSPRQLLDQLVLFLDEIDHLSTESLYTVFEWTRLAVVGIANAFDLIERAMPRLRA--KPERMVILPYTRAQLEEVMRHHVRQNLLSPAGVSLCASKAAA-HGDTRLGLSLLLEAATSLVTQQQPSIFARPSTAPAAAGGGALP--AHQRTVIVFDRYLTPVSPATFMDIL-DQLLGRELSFASSL Fomme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 LVGREEERNQLTEFLHGCLYVSGPPGTGKSAMITEMTRRYAYVNCMSVKSSKDLYTTLLVTLDEIDHILTESLYRIFEWSRLILVGIANALDLTDRFLPRLKA--KPDLLSFLPYTATQVKNIIITRLQSLFIHPAAIDLCSRKVSKQTGDLRKAFEICRRALDLIEVETRPRASIHLNKITAAFSNGTLN--LQQKAALLFDAYLHPLSSSEFREVA-GSLETLGLILKSIL Galma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 LPCRDTERSTILDFLPAGLYVCGVPGTGKTAVLGDCVALLVDVNCATLTDPKTVFVRAILLLDEIDHLLPEALHGVFALPRCVVVGIANALDLAERWMPRLRA--RPSLVVFTPYTVPQITEILKERVNVALFQSAAVELAARKTAG-TGDLRKALDVCRQAIELAESEFRLKRTEALFLCTGYFS---LS--LHPMLVN----------ST--------------------- Gloin1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 LVGRESERQELTSFIGGCMYVSGPPGTGKSALVDEVCQRIARINCATMTSSKDIYAKILVALDEIDHLLTETLYTLFEWSRLVLIGIANALDLTDRFLPRLKS--KPRLLPFLPYTASQIADIVSTRLRSLFLQPAAIQLCARKVASQTGDLRKAFDIVRRTIDLIEQETRPRATVHVARVTATFGHGTLN--LQQKVALLFVTYLQPLAATEFRDVV-GSLETLGLILRGLF Klula1 LATRKSEYDEIMHFFDNSLYITGPPGTGKTAQLDLILRAVAKVNCIALSKPECIFQKLIFILDEMDKLIKKIILDLFLLANVTIIGIANSIDLKDRVLNRLNL--QPKVIHFHPYNSEQMFEIVRSKLSIFIFQPMAIKFATTKCSGSTGDLRRLFDLLRSSVQLLELESLRKVTIHVAKAVSYMNSATLN--IQQKIILAYDYYMKPLSKAEFFESC-YSLQSSGVLLKRLL Lacbi2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 LVGRDMERARLHAFLSGCLHISGMPGTGKTALVRDVLR---YINCIGIAHPQEAAQRIIVVLDEMDHWLHDILQRIF---PMALVGIANSLDLTERFVPVVRS--KPDVLHFAPMQADQVLALLEARLA--LFGRAALQLLARKLTASSGDIRRALDTCRQALDLAENE----VTPHILRVLAMAGHAQLG--VHAKLLLLEAAYVTPLGGSELLDVL-ERLEVQGLAMSRLL Mellp23 IVGRSQEVKKIHQFLGKSLYISGPPGTGKTHLINSILLRVHFINCMAMGNPEQLWRKILIVLDEIDHLATPLITSLLTLSNFTVIGIANTLDLTTRFTWSLES--TPDLIHFSPFDANDMIQVVKQRLKHLLFQSTALTLCAKRVSTVTGDLRTFLAILRKLIDTLESRAIPKITAELIKYLNTCSEQELN--LHQSLGLAFAVYIAEVSECEWQDVIESGLQTRGLLLKEVI Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LVGRVAERETIRQFCAGSLYISGQPGTGKTALLKEMIRKVLTINCMTVKDPKLVYHKMVTILDEMDQLLTEVLYKLFQWSKLTLIGIANALDMTDRFLPRLKA--KPQLLNFNPYQVSEIREIIMDRLFSLLMQKPAIELCARKVAAATGDLRKALDICRQTIEMVELETKPKVTIHVKRALTAFGSPMLN--IHQQIVLVFDHYIGAVSRGEYQDLI-NMLEANGLILEAIL Mucci2 ---------------------------------------------MSVREPKQIYQKLVVILDEIDSLITDVLYKIFEWARLVLIGIANALDLTDRILPRLRA--KPQLMNFNPYQVSEITSIIRDRLFSLLIQANAIELCARKVAASMGDLRTALDVCRQAIELAEMEQKPKVTVHVMKVLNVFGSSTLN--LQQKIVLFREQYISAVSRTELNDLM-TLLETSSIILKSWM Mydma ----------------------------------------------------------LLVLDEIDQLESDVLYKLFELPRLTLIGIANALDLTERILPRLQT--KPALLQFTPYSMPQIVSIIQERLGKVIIDPMAIQFCARKVSSMSGDIRKAFDILKRAIEIVELEIRKKVNIHVSAVCNMFNSQLLP--LQQKLIILYECYINCLSEEEYNNAC-SLLDSQGILMSSIL Neucr2 LIGRDDEREKLNTFLSGCLYVSGPPGTGKSAIVNKVTDRKAYINCMSIKSSKDLYVTLLVVLDEIDHILTESLYSLFEWSRLALIGIANALDLTDRFLPRLKS--RPELLPILPYTAPQVKNIIITRLKSLFFHPAAIELCSRKVSSQTGDLRRAFEICRRAIDLVESETRPRVSIDLSKVTAAFSNGTLN--LQQKAALLFEAYLHPLSSSEFREVV-SSLETLSLILRGIL Orpsp11 FIGREKEKELIINFWTSSLYISGCPGTGKSALINYISKHVTYINCMSLKNPKMIYKKL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 LVGRDAEREKLVSFIGGCLYISGPPGTGKSAMVQEVCGKVSHVNCASMRISRDVYSRLLVTLDEIDHLLNGVLQSLFEWSKLMLIGIANALDLTDRSLPQLKA--KPLLLPFLPYSAASIADVMTNRLRSLFVQPAAIQLCSKKVASQTGDLRKAFELIKRAIDVIEQETFPRASIHIARITSAFGQGTLN--LQQKAAIAFDTYLHPLTATEFKDVL-SNLETMGLILRRLL Phybl2 LVGRGNERSTMMDFWPGCLYVSGSPGTGKTAMLTEIIRNVVMVNCMSVGDPKAIYTKIVVVLDEIDHLITDVLYKVFEWARLVLIGIANALDLTDRILPRLRA--KPQLLNFNPYSVSEITSIIKDRLYSLLIQSAAVELCARKVAASMGDLRTALDVCRQAIEMAENEWKAKVTIHVMKVLQVYGSPNLN--LQQKVVIFREQYISPVSRTELNDLI-SMIETTGMVLDTWI Picst3 LPTRDREAHRLNDFFPNSLYISGPPGSGKSAQISVSFNKLISINCMSLNNVEHIFHEIVVALDELDSLLTHILFELFNCAKLILVGISNALDLSNKFLPRLKR--NPQSEQFLPYTAEQIRLVVITKLKSLLFHPVALMLCCKKSASITGDLRKAFDICYKSIESLEKELVPQVLIHVAGVCSSFGENSLN--LLQKAVLFFDFYLGILKKGEFLEIL-SALESSSVVLKRLL Plicr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo VISRDSETQTIKRFLGSALYICGQPGTGKSLTVTSLLTKVVYINCMGFKDAKEAYFNICVVLDEVDQLISADLYRIFEWPKMILVGIANALDLVQRSLPRLSS--SPTLVHFAPYNRDQIYHIIYGRIESIVCEDEALLYLAKQVEVNNGDIRKALDICRQLISVKQVDYL--ISLDMMDVIDIFGQQNLP--LHGQLIVLFKTYIDPVNRNEFYDVL-SSVTSTGLILKPLL Pucgr2 FLGRSKELHKLKKFLSGSLYISGPPGTGKTHMIKSVLLQVHFINCVALNTSEQLWNHVLIILDEIDYLAAPLITPLLSLSNFTIVGIANTLDLTTRLVKSSAS--SPQLIHFTSFESTDLVDIAKQRLRHLLFHPAALQLCAKKVAAVTGDLRTFLSILRKLVDSLEQNAIPKISPDVVKYLK-TSQAELN--LHQSLVLAYEIYINPVSESEWADLLESGLQTRGLILNQLL Punst1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ----------MSQFYPGCLYISGMPGTGKTAMLTEVMRNINTVNCMSIKEPKQIYVRLVVVLDEIDSLITDVLYKIFEWARLVLIGIANALDLTDRILPRLRA--KPQLLNFNPYSVPEISTIIKDRLYSLLFQPAAIELCSRKVAASMGDLRTALDVCRQAIELAEMEQKPKVTIHVMKVLNVFGSPTLN--LQQKIVL-----KQPV------------------------ Rhoto1 LTGRTDQHETLLAFLPAAMYVSGPPGIGKTALLASTIAGVLVENCATIAGQGSVWERLLLVLDEIDHLVSDLLSSLFALAPLTLIGIANDLTLKALALPTLAT--NPIRVHFKPYSWQELVAIVAQRLSLLLIDKPALERCAKKVAAGTGDVRTMLDVVRRAIALVAADQSPKASMHVSAALASAGLTALQGGPHQRVALAYKAYLRA--ASAYAETV-GMVEDLGGLMRRVI Rozal11 YVGRQKERDTIQEFINGSLYIAGCPGCGKTALMAQILEVHTFLNCMTVEEPRQIFSKLLLVLDEIDQLLTDILYKLFEIPKISIIGIANSLDLTDRFLPRLKL--KPKILHFQSYKINEISDILKKRLEFVKVQDIALELCSRKVVA-IGDVRKGLDFILQAIEKAEIKGKVEVTVHMVQVLNSIQPNSLN--IQCK---VLKEYTSGLSRSEFLDIC-STLETTGIILESLF Sacce1 LPARTAEYEQVMNFLSDSLYITGPPGTGKTAQLDMIIRAVTSINCISLGEPSSIFQKIVVVLDEMDRLLHRTILELFLLASFVLIGMANSLDMKDRFLSRLNL--DPQTIVFQPYTAEQMYEIVIQKMSSLIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRGKIGLYIAKVFSFVNNNSLN--IQQKLILSFDHYLAPLQRNEFLEIC-TILETCGLILKPFL Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 VVGRENEKSIVESFFGGALYVSGAPGTGKTVLLHNVLDNVCYINCMTINEPKAIFEKIIIVLDEMDHLIAQVLYTLFEWPRLILVGIANALDMTDRFLPRLRT--KPKLLSFTPYTAQEISTIIKARLKTAFIHPAAIELCARKVAASSGDLRKALDICRHAIELAEREWKPRASIHVVRATSAMSQSALG--LQQKAILVFEKYIYPLTSSEFCDVA-NSLETLAITLKRFF Sorma LIGRDDEREKLNTFLSGCLYVSGPPGTGKSAIVNNVTDRKAYINCMSIKSSKDLYVTLLVVLDEIDHILTESLYSLFEWSHLALIGIANALDLTDRFLPRLKS--RPELLPILPYTAPQVKNIIITRLKSLFFHPAAIELCSRKVSSQTGDLRRAFEICRRAIDLVESETRPRVSIHLSKVTAAFSNGTLN--LQQKAALLYEAYLHPLSSSEFREVV-SSLETLSLILRGIL Sphar LIGRVKEYKQVQDFWSGALYISGSPGTGKTASVDMVEKLVVKINCMSVITPRAIYTEITVIVDEVDALSRNVLYHLFELPRLILIGIANTLDFTDRLLPRLRA--KPMSIVFNPYTRAEIVAILQGRISSVVADKMAVEFCARKISATSGDIRQAMEVLRKAVVVAAEQSKIKVSVHVLAVFKNSNSAILP--LHHLIILLHDTYGAPVSNTDVTDIL-EMLQGMGILKGHIL Spipu1 LVGRETERRTIQTFWPGSLYISGCPGTGKTALLEEIVNRIVKLNCMSVKDPKMIYPKLVVIMDEIDSLITEILYKLFEWPRLVLIGIANALDLTERFLPRLKA--KPQLLNFNPYEIKDITEIIKQRLKCLLMHPMAIELCARKM-AGTGDLRKALDVCRHAIELVEAETRPKVTVHILSATNVFGSPNLS--LQLKMVLLHETYLIPVTKTELQDLV-TNLETAGLILVNLL Sporo1 LSGRSDQRDTLLAFLPAALYASGPPGIGKTALLSSVLSKVCMRNCSAVGTGETAWERLLLILDEIDHLCTDLLNALFSIAPLTLIGIANDLTLKALNLSSVPSPLKPINLHFAPYSWQELVKIVSQRLELLLIDKVALERAAKKVAAGTGDVRTILDLVRKSISLSTSSLSPKASMHMTTALSSTGLSTLN--PNHRFVLAWKVYLKSVM--SFGQAV-EMVQDLGGLCRKMV Stehi1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 IVGREKETKEIQTFVDGILYICGPPGTGKSATMTQFTQNVVTINCVSLKKPDLIYEQIILVLDEIDYLSSKIMYSLFEFGQIRIIGIANALKLTDSMLPHLRR--TPIVLRFKPYTPAEITQILSARVSEILVERSALDFLGRKVANATGDIRKALDILRKSIEIVESEYRASVTIHISRVATALGGVTLS--IHEKAVLTFDAYLSPLPRTEFATIV-ASMLDNSVILKRFF Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 LVGREAEREQLTAFLGGCIYISGPPGTGKSAMITSLTKRSAYVNCMSIKSSKDLYHTLLVTLDEVDHILTESLYRVFEWSKLLLLGIANALDLTDRFLPRLKS--KPELLPFLPYTAAQVKNIIITRLKSLFIHPAAIELCSRKVSSQTGDLRKAFEICRRALDLVEAETRPRASIHLNKVTAAFSNGTLN--LQQKAALLFDKYLHPLSSSEFREVV-GSLETLGLILRSIL Umbra1 LVGRSQEKEVIIEFLSGCLYISGSPGTGKSAMLREIMAKVCSINCMSIKEPKAIYSKLVVILDEIDHLLTDVLYKIFEWARLVLIGIANALDLTDRLLPRLRA--KPQLVNFNPYKVEEISAIIKDRLSSLIMQPQAIELCARKVAAATGDLRKALDVCRQAIEMAEIEAKPKVTIHVVKVMNVFGSPTCN--LQQKVALFQEQYITPVSRTELNDLV-SMLETSGLVLQSWI Ustma22 VVGRESERVAIQLFLAACLYVCGLPGTGKTALVRSVL-RVAFVNCMTLSHPRLIFAKVLIVLDEMDHLLQNILYKIFSWTACGLIGIANSLDLTERFVPLLAS--KPALLHFRPFDADEIVSVIRDRLSALLFTPTAVELLAKRIAAATGDLRKALDAARLAVELVENEQRPKVGAQILKVLTVLGSPNLG--VHPKLVLVEATYFTPLEASELLDVF-DMLEVNGVTIARIW Walse1 --GRESEIEAIRSFL--SLYVSGPPGGGKTAAVKLVVNRMHWTNCMALSGVDNLLDELLVILDEIDTLPHLELFKIAAEN---LIGIANALDLTSNQLQN--S---PVHLQVHPYTAQQLSNIINDRLGEYLFMPQALELLSRKVSAMTGDIRQVVSVVTLCLDTVEKEQKTKVTMTMLKSITASNKSALN--LHSKIALLYESYISPTSKSDFIDLV-NVLTSSSIIEQDVM Zygro1 LVTRKEQFKYISEFLSNSLYITGPPGTGKTAQIDAIVRAVSTINCIAINDPSTIFHKICVVLDEMDKLVHRMIFELFLLARLVLIGVANSLDMKDRFLSRLNL--RPQTVVFQPYSADQMFNIVMKRLDSLIFNPMAVKYAAKRCSGNTGDLRKLFDVLRSSVEVVELERITKVNLHVAKVFSFMNHNSLN--MQQRTILAYDYYLSPLRRNEFLEIC-NALETCGVILKKII [Cluster3244.fasta_al_trimmed; alignment length = 101] Allma1 AAFQ--KMLEEIQAKYNRQLVQVRTQIQLKERERKVSEIQIRELEAAKTNTFVSVGKMFLQMPIVNQLQLKVASLADDVAVLTKKLVKSVADCQSALNEAI Ashgo11 ----------------------------------------------------------------------------------------------------- Aspfu1 EALQ--KLLQEIEARSQQQIGVTKAQITAKQKNVRLLELTSKEIGSLDTKVYEGVGKMFVAVPVDKRLTSERTELKTDIEGLEKKLEMTYKNSRENLEQIL Aurde31 HTLR--KILDQIQTTSHKALQIARAQKQSKERELKSAQLTIAELTAIDVSMYKGVGKAFMMVPMETNLRMQEKELAEAISNINKKLEKQFNDAQNQLRDII Batde5 EVFE--KAAIEYQTKTSRQLAMVRGQLQGREREKKLSELTAKELEPLTVLAYRSVGRMFIKEDLKDELHKKSASASKEIVAMERALEGDLKDTERTLQDLI Botbo1 ETLH--KILQQIQQTSSRALSISRAQTAQKERERRILQLTIGEISSIDVNLYKGVGKMFMQVPLEKDMKSQEKELTDDISNLNKKLEKQYNDAQSQLKDIF Botci1 EALQ--KLVNEIQSQAEQQISVVKSQISLKQREIRKLELTSTEVSTLDTNVYEGVGKMFVFSPVDKRLNRETKDLKSDIDNLGKKLETTYEKSTENITRIL Caeel ----------------------------------------------------------------------------------------------------- Canalb1 ----------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------- Capow DELT--KSFLELQGKTNRQLRVAHAQAEAAERAGVRASLTTKELAQLETRTYKSVGRAFLFQPVLEELESVAAKSKVDVVKFQKSYEAQMRETVAALQKNQ Catan2 EA-Q--RQILELQTKTNRQIVQVRTQIQVKEREKKIAELQIRELNAANTKTYTSVGKMFLHIPILSQLQLKGQSLEDDVNVLGKKLEKTYKETQDGVKEAV Cioin MELR--KAFSDLQMKTQNQMRISDGQINAMMVEKKKTELAISEVSSVDAKMYESVGRMFVLEPVMKNLEAQHKLTDTKIKELEAKLEKSVKSSEENLREMV CocheC53 EALQ--KVLQEISQKAEQQLVIVKQQKAARARESRMLQLTSSEVSSLDTKVYEGVGKMFVCTPVQKRLEQESEALTKEMANLDKKLEKTYANSKSSLEQVL Coere1 DTMQ--QVYLKVTQKSQKQLNQIDAQISSNQRDIRLASLTKRELDGVSVPLYKSMGKMFVQESMLEDIDKETSNANSLIQALEKKVSRSLEEATGNLKDII Conco1 SEAQ--QLLYAIQTKDSIQLNIVNTRLQTKERDNRVIDLVQKELSTIEHSAYKSIGKMFLYTPMKTELEDKKKENLENIQALKKKLSKRVNETQAHLNDVF Conpu1 DTLR--KILVQIQQTSQRALNLSRQQSAAKERERRILQLTINEIQGIDVNMYQGVGKMFMMVPMEQDLNNQEKELTDDINNLKKKLEKQFNDAQAQLRDIF Copci ETLR--KILVQIQQTSKRALDLSVQQTSAKERERRILQLTIDEISQIDIRTYKGVGKMFMQVPMEQELKGQEKELTDDITSLNKKLEKQFSDAQSQLRDIF Croqu1 DEIH--NILGQLQLRVGRELNKNRAEATKKARELKQAALTLSELSRLELKVYKPVGKMFMLKPIEAELRMKQKLAQEDETRLQAKLEGEVEANQRALREIM CryneH991 DTLR--KILLQIQTQSQKQLAVVRAQITSKEKERRILALQMKELGNVDGGMYKGVGKMFIEQPINKENAEQEKQLAEDVQNLSKK---------------F Crypa2 EALQ--KLYGEIQTQTQQELALGRSQMASKQREMRLTQLTLSEISSLETPVYEGVGKMFVSAPMKSKLQSQMKQLEADVESLNKKLDTTAKNSQDHIEAIL Debha1 ----------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------- Dicdi MEILDKQAFFETREKLSRSLNIIKQRIQIAENDRKKCLITINELESLETKTYKAVGKMFVISPLKTELKQQVQKDEEDVKGLINQIDAQITDTERSLNELV Dmel ----------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------- Fomme1 ETLR--RILQQIQATSQRALSATKATAATKERERKILQLTMDEISSLDVNLYKGVGKMFMLTPMEKELKSQEKELNDDINNLNKKLEKQFNEASAQLKDIF Fusgr1 EALQ--KLVREIESQAQQQIGLARTQMTSKQREQRLVKLTMNEMSTLDAVVYEGVGKMFVSLPLRQKLEGQTQTLEGEVDKLSQRLETTHKNSREHIEQML Galma1 ETLR--KILVQIQQTSQRALNVSLQQTSVKDRERRILQLTIDEISQMDVNLYKGIGKMFMHVPMESELKTQEKELSDDITNLNKKLEKQYNDAQGQLRDIF Ganpr1 DAVR--RLYMECQVKFSRDLNAVKLQIAQKDRDRRIHDLVQQELAGLGKRTYKSVGKMFLAAEISKDLKVESKSLAKESEALGKKIERSSNDIQNLLRDVT Gloin1 EALR--KILIELQNRNNRQLVTVQAQIQVKEREKRLAELTKRELSALDTKTYKSVGKAFIKADLNKEMDDKAEKAANDLVTLEKSLERNINDSQNGLREII Hisca1 EALQ--KLVQEIESRTQQQINIVRSQITGKQRELRLLELTSNEISQLETNVYEGVGKMFVANPVNKRLSAEKGELKTAISNLEKKLETTHKNSRQHMDQIF Klula1 ----------------------------------------------------------------------------------------------------- Lacbi2 DTLR--KILVQIQQTSQRALNLSVQQTAAKERERRILQLTIDEIKQIDVNMYKGVGKMFMMVPMEEELKGQEKELSDDISNLHKKLEKQYNDAQSQLRDIF Lenti61 DTLR--KILVQIQQTSQRALNISKQQIAAKERERRILQLTIEEITSLDVNLYKGVGKMFMNVPMEKDLRAEERELTEDIKNLEKKLEKQFNDAQAQLRDIF Malgl1 ---------------SQRELSTVQAQMKGRSREARVQELTMEQLQKLETRLYKAIGKMFMEQSIMNEAQKRRDDALEENKMLEKKYEKEANEAQTHLQDLV Mellp23 DEIH--KILTQLQIRTGRLLNKSKSENLSSSKDLKQIKLTLHELNRLGFQLYKPVGKMFMLKPIKDELIQKEKIVQENQSRLETKLESEVETNQRALREIM Mnele AELK--KAFTELKNKTATRIKAVDNQIEQCKNRGKHAELTYMEVKQTDTKLYESVGRMFVLEDILEQLKDRAANSRESIQKLENQLSKNLKESENALRELV Monbr PEIR--KAFEEVQRQTAVKVQLTEQQIQKYSGDKRRAELTLAEVNQVDTRLFRAVGKCFVLETVVSGLDNKVAECEKEVASLQNKMEESLAQSKANVEELL Morel2 QALG--KIVHDLQNKATRMVASVQAQIQSREREKRLSELTNKELSALDTVTYKSVGKMFVQEPLTKELTERATEMDKDMAALEKKWERNKTEAQGNLGELV Mucci2 DTIR--KVFVELQSKSQQQANTVKAQIAGKQRERKLAELTRRELDGLDTKTYKPIGKMFIQSPMKKQYVDSIAAADADIKNLEKTWERSASDAQGNLKDIL Mydma ----------------------------------------------------------------------------------------------------- Neucr2 EALQ--KLVREIEAQAQQQIGLVRTQQASKQREMRLAQLTRNELATLTTAVYEGVGKMFVSVPLKDRLSTEMKEMETEVENLGKRLETTAKNSQEHIEKML Orpsp11 ----------------------------------------------------------------------------------------------------- Pench1 EALQ--KLLQEIETRSQQQISITKAHMTAKQRDIRMLQLTSKELSELETRVYEGVGKMFVNVPVNKRLTRESGEATTEISNLEKKHETTNQKSRENLEQIL Phybl2 DAIK--KVFVELQAKSTQQVNQVKSQIQAKQRERKMAELTRRELDALNTKTYKPVGKMFIQSPMKSQYVNAVAGADESIQQLEKSWERAASDAQGNLKDIL Picst3 ----------------------------------------------------------------------------------------------------- Plicr1 DTLR--KILVQIQQTSQRALTISRQQSAAKDRERRILQLTIDEITHIDVNLYKGVGKMFMMVPMEQELKAEEKELADDIANLNKKLEKQFQDAQNQMRDIF Polpo LEITDMQAFQEIREKLNRNLNNIRQKIQVSDKDRQRCVITLKELETLNTKTYKSVGKMFLVAPLKKELKKQVEKDEEDVKGLMNQIDAQISETEKSLKELV Pucgr2 DEIR--NILGQLQRQVTRELTRCRAELGHKVRVARQSSLTLTELNKL-IRFYQPVGKMFMLKSIDDGLKTKQKSAEDDVNKLITRLEAEVEANQRALKEIV Punst1 DTLR--KILVQIQQTSQRALAVSRQQTAAKERERRILQLTIDEVSSLAVNVYKGVGKMFLQVPMDKDLKNQEKELTDDINSLNKKLEKQFNDAQGQLRDIF Rhior3 EAIR--KVFVELQAKSQQQVSTVKAQIQTKQRERKMAELTRRELDSLQTKTYKPIGKMFIQSPMKQQYVDSISKTDEDINQLEKTWERAASDAEGNLKDIL Rhoto1 D-IR--QVLVQLQAQASRQLSAIRAQLNAREREKKLTTLTLREIEQLQTQVYRGVGRMFVQESIENTLRAKMKESTEEVSVLEKRLEGEITTAQNSLRDIL Rozal11 DEIK--KSFVESQAKFQRQLNSVRSQIQAKDHERRAAMLTLREVSLF---LYKAVGRMFLKDTILSGLNSKIESSKDEVAKLEKNFDRNLKDVESSLRELL Sacce1 ----------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------- Schco3 ETLR--KILNQIQQTSQRAFNFAQQQMAAKQRERRIVQLTIDELSQLDTKMYKGVGKMFLMTPMESELKAQEKELGDDLNNLAKKLEKQFNDASGQLRDIF Schpo1 --MQ--NLASQIQEKSQQQLRTIMVQIAAKERALKISELAKKELEDVDKAVYTSLGKMFMKSDVRTHLDAEMASLREDIEALQKKHETTASNAEQHLQKIK Sorma EALQ--KLVREIEAQAQQQIGLVRTQQASKQREMRLAQLTRNELATLSTAVYEGVGKMFVSVPLKDRLGTEMKEMETEVENLGKRLETTAKNSMEHIEKML Sphar NELR--KVFEETQVQDQQKIRYVESHMEVKQRNIRKTQLTAQELTSMDTKCYTAVGRLFINQDITDGLKEQELVHQTERKNLEQQLEKSLKEKEYAMNELL Spipu1 EVAQ--KVLTEIQNKTSRQLSIVRAQLSTRDREKRVCELTVKELASLNTGSYRAVGKMFIQEPLIKELETRKQESEREAKNFERALERDLNDAQNTWKEIM Sporo1 ----------------------------------------------------------------------------------------------------- Stehi1 DTLR--KILQQIQQTSQRALNITRQQTLNKERERRVLQLTIEEITSIDVNLYRGVGKMFMMVPMEKDLKDQEKGFTDDITSLNKKLEKQFNEAQSQLRDIF Tapde11 ----------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------- Treme1 DTLR--KILEQIHSQSQRNLSVARAQIQSKEKERRILQLTMKELATVPSKMYKGVGKMFMIQPIKNEQTTLEKTMDDDLTNLTKKLERQFEEANGQLKDIF Trire2 EALQ--KLALEIESQAQQQIGIVRTQLAAKQREQRLLRLTMNEVQSFDSVMYEGVGKMFVSLPLQEKLQRQIQDLDGEVDRLNQRLETTHKNSREHIDQIL Umbra1 ETIR--RVFVDLQAKSMQQANSTKQQIQIKERERKVAELTRRELEALGTKTYKPVGKMFIQTPMKESFVKRVGTADDEIKALEKTWERSANDAQGNLRDIL Ustma22 ETLS--KVLEKIQLQTNQQLAALRAQISARERESKLLTLTLTELQAINASFYSSVGKMFIQESILADLTAKHQANSADLDAFKKKLVKQGQDAQAHLKDIF Walse1 EALQ--KVLISMQQQAEKALRSVKLQLTSRTREKRLIELTRAELQTVRGGLYNGVGKMFMAVELMDDLSKQERSISEDIVALEKKMQKELESATANLKDVF Zygro1 ----------------------------------------------------------------------------------------------------- [Cluster3245.fasta_al_trimmed; alignment length = 211] Allma1 LSTLEKRMYMKVVNVLAKKNYLEIKEEEKEKV-DELE-YEEKLVFNYIKAVGTEGIWVRTLAIKTSLH--QNSLSKALKKLEQRGLIKQVKSVKGSKKFYMLAELQPSNEVTGGIWF-TDQELDLNFVNTVCLRAIARKS-FPLTITKITREINKIKI--TNVE-LTHADIEAVLDMLIFDSKIEKLAKFPCGVCPVRGAVNPRDYINDWL Ashgo11 LSDTAQELLMAHAQELLDKNLIRLNVSEAQKK-SGMS-SDEALVYSYIEASGREGIWTKTIKAKTNLH--QHVVLKCLKSLESQRYVKSVKSVKPTRKIYMLYNLQPSIDVTGGPWF-TDSELDVEFINSLVWRHTSERT-YPSTTEEILKFISAARV--STVE-LSKSDIRSLCEVLVYDGKLEKV---ADQDFSVFSVISPSAYIDEWN Aspfu1 -NELASKLLLQCTQLLVDQKLFRLSREDAEKL-QNLS-PDESLVYNVIHSTGRNGIWVRAIQSRTNLH--KSILDRCLKSLEGKSYIKSVHNVKPSRKMYMLAGLAPSEDVTGGAWF-TDGVLDANFISTVIEYTVSRKS-WYPTVAMITAAVNESGI--TPVR-LGEESIIQLLEMLCYDKKL---TEVPCGPCPVFGAVSPETYFDPWL Aurde31 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 ------------------------SIFELFRT-GSMS-DNERIVYQFIKASGNKGTWIKDIKVKSGLH--AQIVTQMIKNLEKKVLIKAVKSVKPTKKVYMLSELDPSVELTGGAWY-TDQELDVEFIDQLIYKYICSKS-FPPTCNDLHKWISKSGI--TTVQ-LSHTDVQSLIDRLIFDGKVEQITDVPCGRCPVFGPVSPSGYFKKWL Botbo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 IAALKKVLLLAVTQGLTNDKLFKVTQEEAKNY-RSLS-SEQEIVYALIDEAGQEGIWTKTIKARSNLH--DAVFRTALKHLETKHLISEMKSVERNRKMYIKSSLQPSDRATGGAWY-TDNELDEEFITQILFDHIHRKS-FYPTLNELTSFIENSGA--TAMT-LTAQDIQQLLDILIFDNKIERVTDVPCGHCPVVGPVGPSTYFQTWL Caeel AAESESQVRQTAINSLLSSKKLAITSEQIAGT------EEEQVIYSLIEESKTRGIWIKELREGSGLN--QLQLRKTLKSLETKKLIKTIKAVGTTRKCYILFSIEPDMSLTGGTFY-SDQQLDSELINTLCGSYAASRR-KHIRPQEIAQFITEKRV--LNVP-LSLEDLERILEVAVLDGTIERRVSVPCAICPVVYVISPQSYMKNWL Canalb1 VSDKARHLLMEYLQELVNGKYVKIAEEEAKKV-SSMS-DDEAMIYSYIEASGREGIWTKTIKAKTNLH--QHIVQKCLKNLENNRYIKSIKSVKPTRKIYMLYNLQPSIDVTGGPWF-TDSELDTEFIETLCWRFIVGKTMYIVNLDQLVEFINNSNI--TSVE-LGINDIRSLCDVLIYDDRIEEVLQQNQSDFSVFSTIQDLQYLDSWM Cangl LSDRAKELLMSIVQELLDKNLLKLDFFEAQKK-STMS-AEEALVYSYIESSGREGIWSKTIKARTNLH--QHVVLKCLKSLESQRYVKSVKSVKPTRKIYMLYHLQPSIEVTGGPWF-TDSELDVEFINSLVWRFVSECT-YPCSLEDILQFIEQAQV--ANVQ-LNLGDIRSLCEVLVYDDKLERV-MYAESEYSIFTVMAPSSYFDEWV Capow VVSLEQQIIAAAINKLLSSGLVEMLIASASKL-AGMD-ADERLIYQTIESVKNRGIWTRDLRHKTNIG--IGQLNKTLKKFETAKLIKAVKSVASKKKVYMLYDLEPDKTLSGGAWY-SEQEFDSEFAQQIVLRYLKSRY-ESVSCEEVTQHIADIKL--ATIA-LSFQEIHEVLISLVYGG-ALIVATVPCGVCPVFGIISPETYMDEWF Catan2 LSVLEKRFAAKVMQALTRKNFIEIKAEEQEKV-GEMD-KDERLVYSCIKAVGAEGIWIRTLQAKTALH--ANVLNKALKKLEQRAMVKTVKSVKGNKKLYMLYELQPSSEVTGGVWF-TDQELDVDFVDTICVRFVAAQS-FPPTLSMITRNIRDSRI--AN---------------------LEKISQMPCGVCPVRGAVNPFEYMTKWL Cioin PLTLETEIRVTAINRLLTMGKLELTPSAVGSI-SGVD-NQEKLVYQIIESAGNKGIWTREIRYKCNLM--LTEVNKILKNLESKKIIKAVKSVAAKRKVYMLYNLQPDRSVTGGAWY-SDQDFESEFVEVLCFKFLQQKC-E-ASSEEVLEFISKLGI--SKVT-LSPEDIETILNTLIYDGKVQQTARTPCSLCPVFGEISPENYMDEWM CocheC53 SLSPADALLMELLQELGDRHLLKITREEADKL-RRLT-PDERLIYSYIDQAQTEGVWSKALRSRANVT--QQTLTKCLKSLESKDLVQSVMSVKPNRKMYLLKHLTPSEDIAGGPWQ-SEGDFDMALIDTIVAQHVENET---PTAASVANWLNSKEIL-RGKS-VREDDMEQLLEMMVLDDRLEKIVDAPCGNCPVFGEISARTYFGQWL Coere1 MGDVDGAIIVNGVNRLLKDGKLELSSDEMKLM-GAMS-EDEKLVYKHIENSGNEGIWVRILKQLTNLP--QTVITRSLRALESQVLIKSVKSVKPTRKLYMLTSVSPSSEITGGPWY-TDQEMDTDFIEQLCHQFIYAYS-YPPTATQIKRFIAENRI--SNVD-LSLDNIEELLTMLVYDGKIERITDIPCGRCPVAGSITPAKYFSQWL Conco1 LNDLQVEINLDSLNQLLNTNLIELDLEEQSIL-SKLN-SDQKRVYNVIKDSSTEGIWIRNIKQITGLT--DHQIQQSLKHLERHYIIKSIKSVKPAQKLYILSHLTPSSEITGGTFF-TDQSFDDELVNNLCLNFIKDHSLSPPTLSEIHTHVRENST--ADKD-ISEDDTLQILKVMSYDASVPVRTDIPCGVCPAM-------YYKDWI Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 LSVLKDSLLSTLIQRLMTEKLLIVSAIDAEKY-RHLN-REQAMVYEMIEDAGADGIWSRTLKARLGMH--DSVLKAHLKFLESKVYIKDMKSVEPNKKMYIKASLRPSDKATGGPWF-TDGSLDEAFISELIFDYITRQS-TYPTTRHLAEAISTGGI--TSNTTLTIADVQQLVDVLVYDGLVEPVTEAPCGNCPVFGPVSPGNYFQRWL Debha1 -SEKARTLLLMIAQELINRKLVKLSLSEASKI-TSMS-EDEAMIYSYIEASGREGIWTKTIKAKTNLH--QHIVVRCLKALENQRYIKSIKSVKPTRKIYMLYNLQPSIEVTGGPWF-TDSELDTEFIDSLIWRFVASKT-YPVNLDTIIEFITSNNI--TNID-LAINDVRSLCDVLINDDKLELILVTNQS-FSIFSVIEPSAYLDSWI Dekbr2 VSDGAKLMLMKLAQELLNHGSLKISEQEAQKV-SGMS-NDEAMVYSYIEAAGREGIWTKTLKVKTNLH--QHVVLRCLKSLESQSYIKAVKSVKPQRKIYMLYHLTPSIEVTGGPWF-TDSELDTDFIDSLVWKFVASKT-FPPTLARIGQFIASSGV--TTVE-LTSDNVKSLCDVLVYDEKLEMVQPQNDEIFNIDRTMDTANYLDSWY Dicdi SEELENKFIVKVINNLIKQGRLMLNPEDQAKF-RGLG-VEDFLIYQLIEASSNTGAWTRELKNSSGYQ--QVQITKILKTLESRKLIKSVKSIQGRKKVYMLYNMEPSREITGGQLY-SDQSYDHQYIQIMIKTFVDNK----VDLADIITYLRKVAEEATSQS-LGPEDIQALVNTVIYDGDIEEMCNMPCGNCPVFGLVSPKRYFKQYL Dmel ----SQLLRVEALNILLQEGGIEIDPEKKSALPKDAD-NEEKVVYGIVEEGGNKGIWIRDIRMKSNLN--MIQLNKILKNLETKKLIKAVKSVNSKKKVYMLYNLEPDLSITGGAWY-QDQDFEVEFVDVLCLRFLQMKR-D-CTVNEVQKFISDLGI--SKVN-LAEADLETILKTVVYDGNAERVVQMPCGICPVIGDVTAITYMRDWL Enthi -----------------------------------------------------------------------------MKAKGTKKQIVEKKNVF----------------------F-TKTGLDADFVTTLIFMFLLNKG---ATVIETYDYVRESGI--SNVD-IKKEEILSLLERLVYLGNAEVSSEVPCYNCPYSVSCNPRNAFVDLL Falba LSPNEQAVRAVAINALSRRGMLTFQPEEVVKL-QSMN-QDERLVYTLIKQSDDKGIWTRELRTRANLQ--QVQLQRILRALETRKIVKSLKSVEKNKKIYMLFEIEPSRQVTGGAWY-NEQEFDSEFLGILTYRFIAERS-MPATVEDVVAHIASTRV--SKVP-LKAEDIECIITSLIYDGTVEKLTNIPCGHCQLLGPVNPMNYFSKWF Fomme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 LGVWKEALLARVVQSLTDDKLFITDSQEAHKY-KQCSTDEQVMVYSLIDDSGGDGIWSQTLQKRLNMH--DSVLKNALKQLQTKGLIAPFKNVEPNKKMFIKASIRPSDRATGGPWY-TDQNLDEAFIDELVFDFIKRQS-SYPTVRDIARLLSASGI--THNTILSEHDVQKLVDVLVWDNLVESVTEAPCGRCPVFGPVGPSNYFKRWL Galma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 ----------------------------------SLD-QNARVVYLNVKLAADRGIAVKQLTARCSLH--QKVVQDALKLLEKKGAVKAVKGVKTIRRLYMLANLKPSAEITGGLWY-SDQVLDQEFIEVLCHQYVAEHS-IPVTLGQIRRHVIESRV--LNEI-PTRADIRTILNRLCFDGKVERRTDVPCGRCPVFGAVSPASYYKTWL Gloin1 VFVDEIKIFQDILLNLYEVGLVRKSKETATKL-QALE-NHEFEIYELIENSERKGISKTDIQKQIKLV--QSLVESSLKNMQEQKLIKEVK---KTKKLYMLFDIKPHDESLSRLLY-TNGEPDTFVVESLCYNFIYRRS-FPVTLSKVVQCVQETKV--TEIE-IEEADIKQILDVLIFEGKIIKKTQAPCGRCPFFGEISPSTFFPQWL Hisca1 HKELASALLMKCAQSLVDQSLMRMAQSDAEKL-QNLN-AEERLIYSVVESTGRSGVWTRTIKSRTNLH--QTIVNRCLKSLETKNYIKSVRNVKPQRKMYMLSGLQPSEDVTGGAWF-TDGVLDSDFIRGLIEHWVSSRS-WYPTVSDITNAINNSGL--TPVT-MGESSIAQLLEMLCFDGKL---TEAPCGRCPVFGPVNAENYFDAWI Klula1 LSDPARELLMQYVQELLDKNLLKLDAAEAEKK-SGMS-SDEALVYSYIEASGREGIWTKTIKAKTNLH--QHVVLKCLKSLESQRYVKSVKSVKPTRKIYMLYNLQPSIDVTGGPWF-TDSELDVEFINSLVWRFTAERT-YPTTIEEILEFISESGI--STEQ-LTKPDIRSLCEVLVYDDKLEKV---KREEYSIFNSMAASSYFDEWT Lacbi2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele ----ESQLLVTSINKLIKAGKLELDAKAAEST-KGMG-QEEKIVYNIIEKSGNKGIWVKEIRTRSNLQ--LTQLNKVLKSLESKKSIKSVKPVTSKKKVYMLFDIKPDSSLTGGAWY-SENDFETEFVDILTLTFLQRQR-S-CDIKQVKHFISQLGI--SKVE-LEDAEVKQILESLVFDGFATRLAKAPDDVCCTLDDVTNSQHLSEQM Monbr MAAADTTISLFLSLSLSPHLLGQIGDERSMKL-SKLS-TQEQLIYGIIEDAGTKGVFHQDLKPKSHLD--PRTINKIIKRLKSEKYIKEASSIKGKKRLYILAELEVDTEHSGGPWY-AGQDFDGQFVDIMCIKQLQERLNRPLTAQEILDFIANSKI--AQQD-LSVGDMEKLLETLVYDRMAIRGHTAPCGHCKETNSLKPTCSLSLSL Morel2 LKAGNNGL-AIAMNSLLGRGFIEVKKEEIGKA-GALQ-GEEQVVYNTIRASGNEGIWTKHLKSKTNLH--EAVIKRCLRALEQKALVKAIKSVKPTRKLYMLMELTPSVEVTGGPWF-TDQELDVDFVEQLCYKYILMKS-FPPSAAMVRKYIMDKRI--SQVD-LSVDDITMLLDVLVYDGKVERFQDCPCGVCPVAGPVNPAGYYNKWL Mucci2 LTTGEWKFSYLAMNSLLKKNTLEVDLRDAEKA-SKLN-DDARLVYNTIRSAGNNGIWTKDLKKKTNLH--TIVLNRTLKSLEQKQEIKAVKHVKPTRKIYMLFSLSPSSEVTGGAWY-TDQELDTDFIDSLCLKYIMSRS-FPPTATEVRRFITESRI--SSID-LSVKDITSLLDVLVYDGVVEKKTEIPCGKCPVFGPISPMNYFKTWL Mydma FIDIEAKIYVKAINRLLSTGQIELDSQAASKT-KGFE-AEEKLIYQVIESSDNKGIWIRDIRFKCNLP--MTQVNKVLKNLESKKLIKSVTSVGSEKKVYMLYNMVPDTSVTGGAWY-SDQDFEAEFVDILCHKFLLQKL-Q-ASSHEVWKYISDLGI--SKVS-LTIKDIETILSTLLYDGMAEMIMRIPCGVCPVVGLVSPQTYIKEWL Neucr2 IQILKDALLMQVIQILCDEKLFVGSREDAKKY-TSLPNSEIMMVYAMVDEAGADGIWNRTIKNKLNMA--DSLMKHCIKYLEQKGYIASMKNVEPNKKMYIKANLRPSDRATGGPWF-TEGELDTAFINELVFDFIKQKS-TYPTVSDIAKFIHHAGI--TNNTTLSEADIQQLVDVLYYDGLVEPVMEAPCGRCPVYGPVSPSNYFRRWL Orpsp11 LPADEKQLLVTVGNSLSKKDLIEISEEEVHKL-RSMD-ANEKIIYGYIKEAGSKGIWQKDLKIKSGIH--QKQVLASLKALEKRKIIKTVKSIKSIKRVYMLYELAPSDEVTGGTFY-QDNELDVEFIEILIYRKILKDS-MPPTVSSLSNFLNNSDLFRSGVS-LDNDDIQGLLDRLIYDGKIEKRTDTPCGQCPVFGEVNPSSYFSKWL Pench1 -AELASKLLLECTQSLVNQNLFRLDREDAEKL-RNLT-PDEAMVYNVIHSTERTGIWVRHIGNRTNLH--KSILDRCLKSLEGKNYIKSLHNVKPSRKMYMLAGLAPSEEVTGGAWF-TDGVLDANFINSVIEYTVSRKS-WYPTVAQITSAVNDSGI--TPVR-LGEESIVQLLEMLCYDNKL---TEAPCGQCPVFGAVSPETYFDPWL Phybl2 --------AHLAMNTLLKKSAIEIDLKDAEKA-SKLD-EEGRLVFNAIRAAGNVGIWTKDLKKKTNLH--MIVLNRALKLLEQKHEIKAVKHVKPTRKIYMLFNTTPSSEVTGGAWY-TDQELDTDFIDSLCLKYITARS-FPPTATEVRRFITESRI--SSIE-LSVKDITSLLDVLVYDGTIEKKTEVPCGRCQVFGPVSPFNYFKVWL Picst3 -SEKAHLLLLNLAQELMNKKLVKLSTTEANKI-TQMT-DDEAMVYSYIEASGREGIWTKTIKAKTNLH--QHVVVRCLKALENQRYIKSIKSVKPTRKIYMLYNLQPSIEVTGGPWF-TDSELDTEFIDSLIWRFTASKT-YPVNLDAIMEFIIANKI--TNID-LGLNDIRSLCDVLVYDDKLELINLNNQP-FTVFAVIAENGYMDAWS Plicr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo SAEVEDKFALLVINKLVKEGRIKFNLEEQSKI-RGLT-ADDMLVYQLIEQSNDKGTWTKEIRTQTNLQ--QTQVTKILKVLETRNLIKAVKTINGRKKVYMAYNVEPSREVTGGSLYGGSQSLDEELISAMCNSFISNK----ADLTEIMNYMKKTGE----QD-LTMEDIQTLVNSLIYDGLIEEMTKMPCGVCPVFGEITPKKYFQQWL Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 LSANEWTFAYTAMNSLLKKNALEIDLRDAEKA-SKLN-DDARLVYNTIRAAGNNGIWTKDLKKTTNLH--TIVLNRTLKQLEQKQEIKAVKHVKPTRKIYMLFNLTPSSEVTGGAWY-TDQELDTEFIDSLCLKYIASRS-FPATASEVRRFITESRI--SSID-LSVKDIESILDILVYDGDIEKK------RMALF------------- Rhoto1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 MEKQEQQIIVNSINVLSTKGYVEFADVEANLL-GKLD-GDERIIYQFIKQADNKGIWTKDLKFKSNLH--QTVITKVLKSLESKKIIKAVKSVKSVKKVYMLYDLTPSRDITGGIWF-TESELDVEFINTMCFKFIQSKS-IPPTAEQVLKIIREAKI--TSTE-IELDDMQSLLDCLVYDGRIERLTSIPCCGCPVYGPVNPVNYLKTWL Sacce1 LSDNAKTLLMSIVQELLDKNLIKLLESEAQKK-ATMS-AEEALVYSYIEASGREGIWSKTIKARTNLH--QHVVLKCLKSLESQRYVKSVKSVKPTRKIYMLYSLQPSVDITGGPWF-TDGELDIEFINSLVWRFISENT-FPSTTQEILEFITAAQV--ANVE-LTPSNIRSLCEVLVYDDKLEKV----EEEFSIFKMFPASKYFDEWT Salro GGSVREKIVLVEAQALTDEGKIELGTELSQRV-AKLE-PDERAIYSAVEAAGTAGIWNARFKSLIPD---RKRLKRVLQQLTRDNLIKEFKPVNSKKPHYILYDLEPDESVSGGVFY-DGDEFDREFINNLILLFLKKRF---ITPDEIASKLNASKV--IKIT-LSPADCEKVLSTLVTD---RLV--VPCGICPVRGVVNPVGYLDEWL Schco3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 LPKNAKVI-SSALNILLSRRLLDPRLDEAKTV-STME-GDEQIVYSFIKNSGNEGIWRKTLTLRTNLH--VSVVDRCLKSLESKNLVKSIKSVKPTRKIYMLYDLVPSTELTGGPWF-TDQELDVEFIENLIYRYVHSKS-FPPTALQIHNWLRSTNI--TKVD-LSLANVISLVDVLIYDGKVEKRTESPCGNCPVSSRVNPITYLDKWL Sorma LQILKDALLIQVIQILCDEKLFVGSREDAKKY-TSLPNSDLMMVYAMVDEAGADGIWNRTIKNKLNMA--DSLMKQCIKYLEQKGYIASMKNVEPNKKMYIKANLRPSDRATGGPWF-TEGELDTAFINELVFDFIKQKS-TYPTVSDIAKFIHHAGI--TNNTTLSEADIQQLVDVLYYDGLVEPVMEAPCGRCPVYGPVSPSNYFRQWL Sphar CEIVKE--LLLKMQ------KIKM-VDPGDRT-VGMS-QKELLVHQLIEDAGSLGIWQRELRIQVSKDIVSTELTKIMKNFMNRGIAKEVKSVMPKKKLYMLSYITPDRSLTGGVWY-NEADFDKEFVNAMCADYCIARG---VSEAELLEHIVKCKV--SQVT-LQVKDVECLMQALVFDGKVQILTQSPCGVCPVFAPISPESYLRDWL Spipu1 LTAEEQTLILTCMNSLSQKQYVDFSAEEATKT-GGMK-DEERIIYRLVKEAKNNGIWLKQLRDRSGLH--SQLANTVIKNLEKKNVIKWVKPVKPYKKVYLLFELEPSTELTGGAWY-TDNEMDMDFIEQLVYKYITMKS-FPPTASAIHKFIGKSGL--TTVP-LSLEDVQSLLDRLYYDGKVTRITDMPCGRCPVFGPVNPSNYFKEWL Sporo1 LGPIEQKLVQDAVNGLLRKNLMQMKKEEAKAM-GAMD-SEEKLVLDYIKEADNLGIWTKTLTTKTGLA--RTTMTKVLKILEGRKSIKTVKSVKPTRKIYMLAGLQPSVELTGGPWF-TDNELDTELVDTLVEKHLHLHS-IPPTIASILDYISSTEI--IQVD-LQPKHVEALMDLMVYDGIVEKVTDMPCGKCPVEAPVNPRDYFKEWL Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 LSKDAQAVASSTINQLLSRRLLEASQNEARRM-GGMD-GDESMVYQYIKSSGNEGIWSRHIKGRTNLH--ATVITRTLKSLESKSLIKCVRSVQPTRKIYMLYDLIPSIEVSGGPWF-TDSELDVEFVGKLIERFINSKS-RPPTAQGIHEWLRGTGL--TDVD-LGIADIYALLDVLIYDGKVEKRTDMPCGHCPVFGVVSPEGYWGDWL Thetr -----SSMSTKLINHLMATFQVVLEQVQAQKM-ARLS-NEEKLVFQAVEETQREGIWTKDLKYKTGLH--KSVIDKALAKLVSVQLIRTFKPASKSRKMYMLYSLEPVVD-TSDVWY-TNQEL-IGFVDNVVLQFIQSRS---VTAEDVAAHLASHEA--IKPP-LALVNVQELIELLIRTGEVARLTHTPCGHCPVFGIISPAKYLDDW- Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 LAVLKELLLARVVQSLSDDKLFITDKQEAHKY-KQCTTDEQVMVYSLIDDSGGDGIWTQTLQKRLNMH--DSVLKNAIKQLQAKGLIAPFKNVEPNKKMYIKASIRPSDRATGGPWY-TDQDLDEAFIEDLVFDFIKRQS-TYPTVRDIARLLSSSGI--TNNTILSEGDVKKLVDVLVWDNLVEPVTEAPCGRCPVFGPVGPSNYFQKWL Umbra1 LSETEKQVVMDGINSLSKKSLLEFQMKDYAKT-SGLD-SESKLIYSHIKEAGNEGIWTKDLKKHTNLH--LNVVNRCLKVLEQKQLVKAVKHVKPTRRFYMLYELTPSSEVTGGAWY-TDQELDTDFIDTLCYKYIYSRS-FPPSAAEVKRFIHEKRI--SSVE-LSTTDIICLLDLLIHDDMIEKKSEVPCGKCPVFGPISPSNYFNKWL Ustma22 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 LSDQAKDLLMPIVQELLDKNLIKLDIFEAQKK-SAMS-AEESLVYSYIEASGREGIWTKTIKAKTNLH--QHVVLKCLKSLESQRYVKSVKSVKPTRKIYMLYNLQPSIDVTGGPWF-TDSELDVEFINSLVWRFASDRT-FPSTIQDILDFIVASQV--VNVE-LTPANIRSLCDVLVYDDKMEKI----DGEFSIFNLIAPSQYFDEWI [Cluster3251.fasta_al_trimmed; alignment length = 425] Allma1 KYAEARRFEISAMTNVMKK-MAKSRAF-QKVPRFLRRRAASHNPKKIPVRLRDRAIQEAFRLKRR-TPFPRR--QARNGT-WLETHLWHVKRFHMRALWGRKVPFTPTQKGARAFYRAS-QHATTVFDHSYCQYEFRGIATVLR-YASGKRPAGMLGPATCLWRMWLWTHPAIENAFVSSVASAVHVEQL-DDIGRLALRGPKSLGLLHSIWRSLTTDASPLPCGSVLGLVWDPRLAYSA-QSTLW--DPAVRSAVRRAKPRELNTRRRANLVPGTRLTPIAKTDVAFPLLVTRAGLDLCIPRGMVLPVWRSLVWAGARPGGL-REHEAGVPAFPFDFALTEAVVAQAKWTARPAAKRVNYSVERPFLLSPALTALVQVRLVVGYATTGRYSLAHGGTAVTACVKVGAVL----VRATSSAEVEV Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 KFVEARAFEINAMENAMKS-A-------QLF-----------------AVVSTRARRSAKKGISKTEKYLNR--QR-DKT-WLETHIWHAKRMHMTTLWGYRIAEAPTAKAFRASHRAS-LHDAILHDESYATIELTGLRRLLR-FATGARPRGLVGPATLVWRLWIRLHPAAFGDAWAALGEALEIADLRDEIVAFELVGPKGSRVLQKFWSAMIPTPGAVPRGMVVGLVLDPRVTYALAHSDIW--DEAARQGVRVPRYRKLDKRRAQNLIPGTPLEPVAD-DARVPMLLIQRGWLLLAPRGWGTSLLHALTFTGTRVAGL-RQAEAGAPLYPVDFAGTRGAAERAKWLRTPRAKRVGYKVRSAFVMRGQGVALVNVRIIIGYISSGSYSLSRGKGFGVGAIAAGKMLEILQVRDRHGATIEI Batde5 EVIQARSFEISSLETALSN-TGAQRVF-QTLPRHMRRRAASYNVKRLPMHIRKRALVQYKKRKATSEEFMKR--PA-HNK-WLETHVWHAKRMKMVEKWGYKLADHPNDKNLRSAFRSS-KNQSVIHDASYQPIELNGVVKLLD-YLNGSRPAGAIGLIEILWKVWLFTHPDTHERILKLL---VSIVSLKGEFCRFEFCGPRSHAILHSVWQQLLISPTSVSPGVVLGLVQDPRLSFVAYQSSIW--DKESRKVALDTRATNINARRSMNLIPGTPLAPSST-DSRIPILLIHRGWDLVIPRGWAKEFWLTFIFSGARVAGL-REFEAAIPCFPYDYPETTCAELEKIYNRTPKAKRPNYQVPSPFVLHSPSLAFVRVVIILGYLTTGHFSLRQGQGQAIGCCSLAKLYNAMQVRGITDALLEI Botbo1 KFADARAYEINAMQSAMAN-AVTHRVW-QTLPRHLRRRAASHDVRRVPVRLREKAQLEPKRGKSKAEQYHQR--QSADKV-WLETHIWHAKRMKMDHIWGYKLAVQPTEKSFRPSHRAS-VHGAILHDVSYSTVQLHALKKVLR-YTGGGRPFGLISPVTIIWRVWLRAHPSAYDDVCRSLKQSIEFSDLRDRFNAFEIMGPKSSQVIKKVWNALLQTPGSVPRAMIIGLVYDPRLNFTLSRSELW--DTVEKD--FTPKFKKLDERKSKQLIPGTSLRALDQ-DDRVPLMLIQRGWTLLAPKGWGMPFLSSLIHTGTRVGGL-REFESGMPAFPEDYPTTRAKQEQERWERTPPAKRCNFGTKHPWLLRGARTALVLVRVVVGYVTSGNFSLQLGCGHAIGAVPARILVGLMRVRDRNGASLEV Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel KFVEARTNSIAQLLKAIDNVTKGPRTAAQRLPRHMRRRAMAYDIRRFPRTMREFAAAHPSRFARRRTKFGRS--TS-TKGIWLSTHVWHAKRFRMIQKWGFKLADRSFQRGFRAVLRDS-NKNCVIRDRSYTCVTIQC-----R----DEEPFGYIGPARF---VHIWIHPSSKLQFMKALLEYIKVSIDAENICRFHLSGPKCLSKLHNYFLSVVFQSS---DGEVINLIEDPRTTWRIRVSKFW--NKEFREMAIEKRMADFHKQNSSNGVIST--------EAKVPIILIIRGADILIPEPFAKDFWVSLQRRGVRASGL-RDLESKALYYPLDDVGSMKKELIEKYLGKPHNRRCKHSVKYPFVCRDLQKMLIPVKLIIGRLVAGEQSVLAGHGVGIGYICANTLSLIASVRNSTSAYVTI Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow QFAAARAREIQTMLHALNEGGGGRRVF-QTLPRHMRRRAMSHNVKRVPKRSRSAAQREPTRMRRRHRHLLKRA-RAKG---WLETHVWHAKRMKMADQWGFRLALRSAQRGMRATHRAT-LHSVTAHDASYGIIELAGLLSVLP-ALTGAVPLGVIGPFSFLWRLWMWFHPACFHAALLALRQAVLVLDRRKEIVQFQLTGPWSHALLNIVWASLLHNAAALPPRTVFALVHDPRTVHQRGHQDLW--DKVSRTFVQDHQVSELHERRQQYLLPNKATIHSEE-DTPIPLILVQTGYSFFAPAKFGSAFWRSLTYAGARAIGQ-EDLESGDLQFPIDFPDTRAMALSAKHSRYPKAKRVNYGTPSPFNSDGQTLILVCIKIIMGFVTTGGYSFTRASGFGVAFCTLASLLELASVRNPRSAMFSI Catan2 RFAQSRAFELVALQATLKR-LSKSRAF-QKTPRYLRRRAASHNPRKVPRRLRERAMREALRRKPR-SDYLSR--QVRNGT-WLETHLWMAKRFHMRAMWGFKVALRPTQKGARSMYRAA-KYASVVHDASYSVYEFSGVAQLVR-YMAGKRRAQLLGPATALWQLWLWTHPLIDERLLASLAHIVNVTQL-TDLCKLTLVGPKSFGLVQAQWRSLLTDPSTLPKGGVLAVIWDPRLSYTAPESTLW--NATSRLHARQGKVRDLHARKHAQLVPGTRLQPNPDRDSTIPLLLIASALDLVLPRGWSLPVWRTLVWAGARPAGL-ACHEAGRAYFPWDYPTTEADEQKQKWMSRPSGKRVNYMVDAPF---------------------------------------------------------- Cioin QHANAAANEIQSMMSAIKQ-SGNKTAL-QILPRHMRRRSAAHNVKRLPRRLRELAQQQCRKKRRRQNEYSKR--AG-KSG-WLETHMWHAKRFHMTDAWGHRVAIHPNDKSFRACYRAT-ANHCLLQDISFKCIQISCQEEIFK---SGECPPQLIGPASIMYQIWLRIHPTLLEKT-NDLISYISITDISSELLRFRLSGPKSSVTL-----EVIASPSSVVNKWIVEHVNDPRLTLSVTSSPLW--NSDARNDISNRRLSDVSTRKNE-----AKKSLKSI-SQPIPVILIRRGWDLIIPAKWATAFWIPLVYNQARVGGI-RELECKRPFFPRDYPDCTMKRKQTVYFRKPPAKRPNYATPFPFLQKNNSNGLICVQIICGFVTSGDYLFCSGGGGGVGFVTLKHLVQVYRLRNPDSAVIEI CocheC53 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 GFVEARSFEINSLQRSLDD-AGNVRAF-QTLPRHLRRRAASHNVKRIPARLRERAIAEYKRRRARREEYELR--QT-GKR-WLETHVWHAKRMNMAEMWGTMIARTPNERSHRAAYRAA-KEKTYIHDVSYVTLEISGIVQLLP-YVGGSRPLATLGPAMALWQLWLRMHPAIGE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 AFINSRKSEMQILKNNMEN-QSSKRVF-QLVPNFLRRRGASYNSNKLPLRLRKLGKAESSRLKLRKRDYQRR--QK-NGK-WLETHLWHAKRSKMAKLWNYKLCLSPNAGGKKSGYRLH-KERCNIVDTSYGTIELIGIEKLLR-YVTGKRPQNYLGPADFLWNIWLFVHPSFYNTLYQQLRTVIQLKDLRNELCQITLFGPKALQTISKVWSDLIRSQSSLPPQAVLGIIYDPRLSVSLSNSKIW--SNEIRENVKNRKLTDINQRRSQALIPGGNIEPSDK-DVQIPILIVNQSIKIILPSGWGKILWNRLVFCGAKHQGQWYLFSSRNLYFPLDYPSTAQCTLKQKYDRTPPAKRINYNVKYPFLFTNSIIILIPVICIIGYITNGGFCPQSGKGVGIGWIKLKSLIEYSAIRNPTSATAEL Conpu1 RFTEARAFEISAMQTAMQN-SSTTRVW-QTLPRHLRRRAASHDVRRVPLRLRERARQEPKRGKGKTESLLKR--QR-DKK-WLETHLWHAKRMKMENMWGYRLAVHPNEKSYRSSHRAS-VHGSIIHDASYNLIQLEGLLSILR-GKSGSRPLDLIGPVTIIWKVWMWCHPAVYQDVFDALHKAVQISNISDSVNVFEIMGPKSSQVIKKFWASLLQTTGSLARGMVAGFVLDPRLKFKLAQSDIW--DESARKSLKKPKYKKLDERRSKNLIPGTPLRALRQ-DDRVPLLLIQRGWTLVIPAGWPMAFLSALTHTGTRVGAQ-REFEAGTPYFPRDYPCTREAKERAEWERKPPAKRVNFGTRSAWLLRGPQVALVRVRLIIGYVTTGNFSLTRGRGFAIGAVPARVYVELQRVRNRNGVFLEL Copci KFAEARAFEINAMHTAMKS-------WILDYPAH-------------------KAKYEPKRGKSKTDSFLSR--QK-DIA-WLETHLWHCKRMHMEDIWGFKLATHPTEKAYRPSHRAA-VQGSIIHDASYSLVELRGLVPVLR-FKTGARPYDLISPISIIWQIWLRFHPSAHDEVVGALKTAIQVTELKDQINVFEFMGPKSCQVLKKFWSSLVQTSGSLPRNMVVGLVYDPRLKFSLARSELW--DESVRLGLAKPRYQKLDIRRANNPIPGTELKPLRQ-DDRVPIILVQRGWTVIVPSGWGMAFWNSLIFTGTRVGGQ-REYESGTPYFPRDYIFTREDELRTNWERKPPAKRVNYGVIHPWLFRGAELALVTVRVIIGRITTGHYSLARGGGFAIAAVPLVKMLELKK----------- Croqu1 KFLNSRAFEISAMERAMKT-AGCQRAF-QSLPRHLRRRAASHFARRLPTRLRSKAKFELRLKAYLTERLRNR--QV-EKA-WLATHVWHAKRTKMIDIWGFRLAKTPTEKCYRSTYRAA-QHGSTIHDQSYSQVTLSGLARVLK-FKPGHRPYGFIGPASIIWCVLLQVHPAIKDQVLDAIRSAELALAVHEDLGSFELTGPRSTEVLGDVMRLLGIAPSVFPSGMVIGLADDPRVHFDLARCQFW--NSQVRK--RHPQFKKIDKRREEQTIPGTRLRLTEE-DDRIAILLVRSGWKVLLPKNWTQAFLVSLVYAGPRLVCL-DQYEAGQRAFPNDFPGLSGAAARSHWERRPPAKRVNYGEEDPFLLSGPVVALVSVRLLIGFITTGKYSMRLGYSHGIGAVSLIEFAKMQIYRNVHEGNLTW CryneH991 KFAQTRAMEIHAFQTAIKT-QGSTRAF-QSLPRHLRRRAASHNPRRVPKRLRSRAAAERAKGNLRTAIFRIR--QR-SKR-WLPTHIWHAKRYHMANIWGWRLPITPTLKSFRPAYRAG-KRKAIAWDMSYGVIEVEGIVKLLK-FENGSRPRGLIGPAEILWQIWIRVHPSIFDQVFSTLKAVLQLRDLRGELESFEIMGPKSGEVLSKFFDVL-GDPAEVPSRTIVGLVHDPRLHFELAQSVLW--DPAARELASEVMYTKLDARRHKLGMPGTRLHPTSS-DNRIPLILFHRGFTLLFPSSWAQYLLTSIAYTGTLIGGL-NEREAGTPSFPEHFGQVKAEEAEKRWERKPPAKRVAFGTSRPWLLPHPFTAVLHVELLIGYTSTGNISLSRGKGHALGMITLAGYLDLLKVRNRDGAEVRV Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi SYVNSRKSEINQFLKAITT-KSNTRAF-QSLPRYLRRRTMSHNVYRLPVHLRKRAQNEVRKAKRRLRDYERR--QK-TFK-WLETHIWHAKRMKMLSIWGHKIAKSINGKGVRSTFRAS-SHFCTLYDCSYQCIEITGIINFFS-YLTGSRPFHFICPAKYLWKIWVWIHPAALNEITFIFEKSLNINNLEQQLQRFELTGSKSHSIL-QVWSLLLRTPATLPKGTVISLVHDPRLVCQVAVSELW--DEEKRSYMSKNIEENVNERRKRNSTTKNQLPPSTP-----TIMLIQRGWDIIVPGGWGLAFWIPLIYAGAWSIGL-EDLEQGLPSFPRDYPDSTTTVLEQKFKKTPPSKRINYSVFFPFVYRGKLAGLVRVSIPIGYVTNGEQSLVRGFGSGVGFCSAVDFIRLHNIQNPKSIILTI Dmel HYAAEALQEIRNLVADCQE-RSSKLIF-QTLPKHMRRRAMSHHPKRLPRKYRQAHKSQSRKYRRRMREYVRR--QR-RHV-WLETHIWHAKRFHMVDRWGHRLPYASCDKTYRACYRAS-AEHCLLQDISFGCVELRGLREGFRTFLSGRRPYGALQRASFMWRLWLWLHPSGAQAVLNQLISVLHLVLLQREFNRFRLTGPRAQKVLKANYCQALSSPAELLSNLVMAHVVDPRLQRSLPESPLW--SKKAR-----ERLAKMSAHKYDAVVPGAPCAFEQQ-MQALPVILIQRGWDVIAPAGYGMTLWLTLTMWGARPGGL-REL-----------PDTSADELRARYFRMPPNKRTNYAVVSPF---------IQIQLVFGYVSTAGFSFTEALVCAVGYVTPAGLQQ---VRDADSASFQV Enthi ELTASRIEEIKKFTDQLNV-YSGNRTVHQAVPRHLRRRQASHFCHVLPHRFIANALREKIRRSRRRRNFKEY--SW-GKNQYLMTHTWHAKRCHMKEMWGVKIADERNDKGLRVLLNAA-EKRSVVYDQSYVEYELENCMKVLK-------NTTKFGPIKVL--IVIFVHPVSKTDIMKAFDKE------MQRLGVFEIIGGNSHRSL-------LRRICNTPNASVIPLINNPISQFNAVSTELVSQTLEQIINLSDVSSFNLEARKAI--------------QKEIPLLLMANGYFLIVPSLFALTCWRRIVWHCVLPLAL-KEYEAGLMTYPDDYVDNQKDILIKQASLKPKSKKMNIQNQIPW-------KIIRFELVVGRIIKGGYSLKRGSGYGIGFIYLNKYNEIIKYRNAFSGILSL Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 KFAEARAFEINAMQNAMDN-IGTQRVW-QTLPRHLRRRAASHDVRRVPARLRQKARSESKRGKEKTEKFLKR--QK-DKT-WLETHIWHAKRMHMENMWGYRLAQTPTEKSFRPSHRAS-LHGCILHDASYAIIELKGLKEILR-FSNGSRPFDLIGPIEVLWKLWIRCHPLIYDEVMSTIKYSIEMADLRDQFNIFELVGPKSSQVIKKLWKALLQTAGSAPRGMVVGFVLDPRLNFKLAASDMW--NDDFRAKLSKPRFKKIDARKSKHLIPGSKLNPLRQ-DNRIPVLLIQRGWTLIIPKGWGMPFFSSLTHTGTRVAGQ-REFEAGCTAFPFDYPCTRAKEERERWERKPPAKRINWGTESPWLFRGPEAAIVGIRLIIGYVTSGHYSLSIGRGQAVGALSLTSYLEIKEFRNKHSAFVEL Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 KFVEARAFEIDAMHTAMTT-SSTHRVW-QTLPRHLRRRAASHDVRRVPLRLRDRARAEPKRGKDKTESFLKR--QN-DKT-WLETHLWHAKRMHMDNIWGYRLAISPTEKSYRPSHRAS-IHGSILHDASYSLVEIACLITMLR-YLSGSRPYDLVAPVTIIWKVWLRFHPSAKTAVVDILKQALEIADLTGQINVFEIMGPKSSQVISQFWSSLLQSSGSVPRGMVIGFVNDPRLRFQLASSEIW--DDTTRNGLSKPRFKKIDERRAKNEIPGTPLSVLRQ-DDRIPILLIQRGWTLVVPAGWSMAFFNSLIFTGTRVAGQ-LEYEAATPYFPRDFPFTREEKDRDAWTRKPPAKRVNYNTINPWLLRGSEVSLINVKVIIGHVTTGHYSLARGHGFAIGAISVTHLLELEQVRNPDGAHLEV Ganpr1 DFASHRAHEIHAMERFLSQLKGGLRVF-QTIARHLRRRAASWNIKRLPKLVRDRAIKETAIRKSKMEDYKRRAGQE-GRR-WLETHVWHAKRMHMVHLWGFKLADHPNDKSTKATHRHA-LHQSFIHDASYRCVEISGVVRVVR-FTGGVRPGGLLGPVTFMWRLWLFVHPSLLTAILASLHASVTVRATPTPLLRFELTGPRSLALLWTVWNDILRSAASLPPGCVLGLVWDPRLRFDAGSSSVW--DEQLRTRLADRVPLELNARRNQNLVPGTPLAPALG-DPIVPVLILQRGVDLLVPQGWGAAFWKAMSFAGGVAGGL-QDFEASMPCFPYDFPSSIKAHAEELYGRKPPAKRVNYGVRSPFVLETPAVALVRVRVILGFVTSGQYSYAEGRGRAFACVALRRLFEMQSVQSTRSALLTV Gloin1 ------------MNDALER-AKNSRAA-QTLPRHLRRRAASHNVKRLPVRLRKKAIDENRRKRRRSAEYKRR--QG-NKK-WLETHMWHSKRMKMTEIWGYKLAEHPNEKSIKASYRAS-EHLSIIHDVSYGWIKISGIVKLFR-YLSGKRPTHLVTPINLLWML-IWIHPSAFEEVLTTLEFAISIQNLQDEFLMFELTGPRSTALLHRVWRSLLRTSTSLPPSIVLGLVLDPRLRFNVAYSDLW--NDNFRNALRDSKVSDLDKRRSKLLVPGQKLLLQPE-DSLIPILLIQRGWNIVLPAGWGMAFWKSFIFAGAWVGGL-REFESGISCFPYDFPGTQKKKAQLEYNARPPAKRPNFQVDSPFLLQGTKNALVRVRIIIGYVTTGQFSFSQGHGFAIGCCSVTGILDLLKVRKITSATLEF Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 KFVEARAFEIDAMQKAMKT-SSTQRAW-QALPRHLRRRAASHDVRRVPLKLRDKARAEPKRGKLKTDKFLSR--QR-DKT-WLETHLWHAKRMKMSDMWGYRLAVHPTEKAYRPSHRAS-VHGSILHDASYSLVEMRGLISMLR-CLGGSRPFALIAPVTIIWRVWLRFHPSAQNEVLANLKTVVEINDLKDRINVFEIMGPKASQVIRKFWSSLLQTAGSLPRGMIVGFVDDPRLNFTLASSEIW--DESIRDALAKPRYKKLDERRSKNIIPGTPLNPLRQ-DDRIPVLLIQRGWTLIVPSGWSMAFFSSLIFTGTRVAGQ-REYEAGTVYFPWDYPFTREKQERESWERKPPAKRVNYGTISPW-------ALVNIKLVIGYVTTGHFSLSRGQGFAIGAIPVTRFFELRQ------A---- Lenti61 RFAESRAFEINAMHEAMQN-SSTSRAW-QQLPRHLRRRAASHDVRRVPLRLRDKARAEPKLGKLKTIDLLRR--QK-DKT-WLETHIWHAKRMHMENIWGYKLAVTPTEKSFRPSHRAS-VHGSILHDASYATIELKGLRTILR-FLTGTRPYNLIGPATVLWHVWIRVHPSITEEAHDALRLSIEMADLREHFNVFEIMGPKSSQVIKKFWNSLLQSSGSVARGMMIGFVHDPRLCFALAQSQIW--DEQTRMKLRKPRYKKLDQRRSNNLVPGTPLKSERN-DDRIPVLLIQRGWTLIIPQGWGMPFLSSLIYTGTRVGGQ-REFEAGCAYFPRDIPATRAYDERETWERKPPAKRPNYGTRSPWLLRGPDVALVNVSIIIGYVTTGSFSLSLGEGHAVGAVPLAQYLELRTLRNRDEAYLEL Malgl1 --------------------------------------------------------------------------------------MWHAKRFRMSGRWGFSLAETPHHKSFRMTWRKT--SHAVMHDASYSAFYVTAFLMLLS-WTSGSRFLRVISPLQVLWVCVLLIHPAAVGDLQCALEHAIAVSRPEEGWNVFEVLGDHAAHALSTVLHQIDSEPTWLPSDMVLTFVIDPRLSSALTDASLQ--DEDLPRYTSARFFQKIDRRRARDVHPRV--------DDTLTIMMIQRGFVLFIPRGWGAVFWNALARTGVQVLGQ-AQLNMGLPLFPYDWVGHDEKERKAHWLARPPAKRVQLMFPYPFAKQGEAVPFVLVLIMAGAVSTGHYALATGHGRAIAALQLDAWLELERVRPAMTASVHR Mellp23 KFINSRSFEISAMERSMKS-SGSQRAF-QSLPRHLRRRSASHFSRRLPTRLRMKSKFEIKHKVYLTQVFRSR--QI-DKK-WLSTHLWHSKRTKMIDLWGYRLAETPTEKCYRPTYRAS-RSGSTIHDLSYSNLTLVSLIQLFK-YKPGHRPYGYIGPISMIWCVLLQIHPAIKDQVIECIHQAKVVLECQEDLGCLELFGPRSTEVLVEVMKLLGLRPNLFPLGMVIGLIDDPRVHFEIAKCLFW--NQEIRL--KKPKFKKLDKRREEQMIPGSRLKPLIE-DDRIPILLIKVGWKLMISNHWIQSIFQSILFTNVRLICL-NQFEDQSPRFPEDFNTLDSLKEKTVWSRKPPGKRINLREMDYFLLNGLIVSLVKVKMLIGFLNDGKFSLRLGNCLGFGSVSFFEFIKIKLFRNRDEGKLIV Mnele DIVDSRSREITAAMEALKT---------LSIPFYMRRRAASHNPKRLPARVRPLDAAPRSKGKEENERMEDK--ENVKKAKRLETHLWHAKRCHMKDVWGYRLALCTTQKGARAAHRAT-NTATTLQDTSYHWVSLSGLHSKL--HVTQHRLGKCLGPVRVY--VYLRLHPAVATSCSD-----LSVKSLRDAFSQFTLHGVRSLELLREIWDELVFH--DVMSGTVLGCVIPPREHKRICPDELGG-DTLFRSALSSTSSVTVTDTVTS--------------RETLPCCIYKDALTLMLPRGTGTRLWISLVYSGGRVVGL-QDTDRSRATFPADYPDTDGREREGKEMRRPPQKRVKYGIASPFVIRDPALHLLTVSLVVGYLTSGNYCLNSGKGGGVALILAGIFKKVREVRNTTSVEARL Monbr QFAAARAKEMKAMEADLEQ-ASKSRRH-KRRPRHM--RAA----------------------------FEARS----SRVRWLETHLWHAKRFQMAEQWGFHVPQKPSDKSERVNYRFV-RDHVSIQDASFQTLVLDA-------HATGQEDGSVVAPISYFWSCWITVHPASLAVVEALLRGALELTHVTEYTNRFRLRGPAALQLLTRAWNEL-RSDAVILANTVLQLVWDPRLQTMTATSAAWFIEEDSRRASSEGQAHVLNQRRAAAPVSGATLQPGDH-DSIVPILLIQKGWDLIVPRRWALPFWMMLVHAGARVHGQ-AELESGQLAFPYHCVGSELDARQRRWQARPPAKRLNYNVAAPFLLGGNPLALHWTRL---------------------------------LRHPDTTWVEA Morel2 NFAEARAFEINALHKAMES-AAAQRAF-QSLPRNLRRRAASHNIKRLPVRLRDRA----KYKKRRAEEYLRR--QG-TKR-WLETHIWHAKRMKMVETWGYKLAEHSNEHGIKSAYKSS-HHQCIIQDSSYGCLEITGIADVFR-YITGKRPKNLIAPATFLWKLWVWIHPSAFESTKSMIQETVNIKDMENSLVMFDFTGPRSTALLHKTWEAIMRSSSSLPPGIVLGLAEDPRLTFTVARSGIW--DAEEREQLLSNMTPELNERRAQNLVPGTKLRPIES-DSKIPLLLIQRGWTLVLPKGWAMPFWKSMIFAGARPGGL-REFETHQSCFPYDFPNTSKKAGEQKYGRIPVAKRFNYGVEDPFLLQTPKMALVRVGVLLGYVTTGQYCYSEGKSYGIGCVTATGLARVIEVRSVRSAKLTI Mucci2 RYALARIMEINDMQHAIKK-ALNELAF-QSLPRGLRRRAASHNINRLPARLRAKAAKEKVKKIKTVQEFLRR--QK-SKK-WLETHMWHAKRMKMKDIWGYRIASRPNTKSVRITYRSF-TRLSVAHDASYACIELKGIVAALR-FIKGNRPTKLICPISFLWKIWLWIHPSAINEALTFIRLAIELNDLRNEILKFELTGPRSTALLNAVWKDLLRSSCSLSPGSVLGLVQDPRLKFDAAETTIW--DKDVRASLFDKRISELNLRREQNMVPGTKLEPTAE-DSQIPLLLIQRGWTVVIPRGFGLAFWKSLTFAGGRVAGY-DDFESGVPCFPHDYPGTTKKAAEQVWSKRPPGKRVNFGIAHPFLICGQRLMLVKIRLHIGYITNGDFSLTLGFGFGIGACTVAGLKKLKDVRNPTSAQLEV Mydma DYAVARAYEIKNLQTALKE-LKHQRIF-QQLPRHMRRRAASYDIRRLPHRLREKAQAEKYKRKPKLEEYTRR--SR-ENS-WLETHIWHAKRFKMVDMWGYRVALKPCDKGYRAAYRAS-QKSAILQDKTYEVIEIKILTEIWD-FVAGKKPKNCIGPIYII--FFLVSHPEISKSVVDIFQILIDVFCHRLDFVIFSLNGPLSSSIVKVHWNSG---------QSVTNVVDDPRFHIEIQEYSLW--NETNRDDIKKKKLSDINKMRSELLVSGSALPIESP---KIPIVILQTGYYLILPSGWAMPFWIALVYQGARVGAL-NEYEALVPYFPNNFPDTRKKENEDLYKRFPPQVKQNYGVANPFVLRDQLLSLVYIRVVLGYILTGDYSLSRGKGAGLGLVTILGLLFLTSFRNIDTCNIEI Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ----ARSFELNAIESALKNNTGNQRVF-QSLPRHLRRRAASHNIKRIPLQFRKKAFWENRKDKRKVEEYNRR--SS-KVK-WLETHIWHSKRMKMCEKWGYKLAEYPREKGRKIIYKDQ-KYTCLLHDASYQCIEINGIKLLFR-YIKGNKPFNTISPITFLWKLWLWVHPSSYQDVLNELDMSVQIEQIKNEIIIFQLTGPRSHAILHKIWKNLLRTPASLPAGVVLGLVHDPRLSNNVSQSNIW--DSELRNQLKNNKCSELNKRRSESLVPGTPLEPLEN-DSKIPILLAQRGWNLYIPKGWAMAFFKPLVFAGARVIGL-NNFESTIPCYPYDYIETKAKEEEDTYNRKPLSKRPNFGIVSPFVLNTPKLAFIRVSIIIGFVTTGHYSLNNAHAKAIGCCSVIGLINMIQVRDPKGA---- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 QLASAHINEINSLQSSIRK-AITTLAF-QSLPRGLRRRAASHNINRLPLRLRVKATQERMRK-PRVEEYLRR--QG-NKK-WLETHMWHTKRMKMTDIWGYRLALYPNIKSERTAYKAS-KHLSMLHDASYGCIEMSGIVRVLR-YTKGQRPTKLVCPVTFLWRIWLWVHPSVFDEVYTSIRHVLQVVDQRGDLVRFDLFGPRSTALLAQLWRDILRSSSSLPPGCVLGMVQDPRIKFDVAYSDIW--DKQLRRDIQKNKIKDLNKRREDQKSNGVKFEFTEK-DSKIPILLIQRGWSIILPRSWGVAFWKSFVFAGARTCGL-HNFESGHGVFPFDVPGTSKNTERSIWAKKPPSKRVNFGVSHPFLLQGDRLALVKVRVHIGYLTNGGFSLSVGGGLGIGACTALGIQEIRNVRNTNTAQLQL Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 RFAETRSFEINAMQNAMKS-ASTQRAW-QALPRHLRRRAASHDVRRVPARLRGRARAEPKRGAANTESFLKR--QR-EKT-WLETHIWHAKRMPMENLWGYRLAITPTEKSFRPSHRAS-VHGSILHDASYSLIELKGLRTLLR-YLTGARPFDLIAPITVMWRVWIFSHPGPYIDVFAALGTSVEIADLREHVNVFEIMGPRANQIIKKFWAALLQTSGSVPRGMVVGFIYDPRLKFAIARSEIW--DDEIRTSLKKPRFNKLDERRSKLLVPGTALAPLRQ-DDRVPVLMIQRGWTLIIPSGWSMPFFSSLTFTGTRVGGQ-REFESGTLCFPRDYPFTREAEERALWERKPPAKRVNWGTRSPWLLRGTDTALVMVRVIVGYVTTGNFSLSRGEGFAIGAISLAHVLCMKQIRDRDGAYVDI Polpo RYVNERKNEVQQLMSAIIV-KNNSRAF-QSLPRYLRRRTMSTRIYRVPLHIRFRARKELRKAKRRLRDYERR--QR-TYK-WLETHIWHAKRTHMINLWKHRIALKLNVKSFRPTFRAS-SHFSTIYDASYGCFELIGIIDMLL-YVTGSRPFHLISPIQFLWKIWIWVHASTIDTVQSVLEEQLQLNSLCGELQRFELTGPKSNAVLAKVWYALLRSAATLPPGTVLSLVMDPRLICKVAISPLQ--DKESRQSMSANIEPIIYQRRK-NPLSKTQF--SSP-----SILLIQRGWDIIVPKSWGTSFWIPMIYAGAWAIAL-ENLEQGIPSFPGDFPDSMTQETVSKYNRTPKGKRPNYCIYFPFVYRGKLAGLVRVSVPIGYVVKGEQSLVRGIGSGIGYCSAVSFVNIHLIQNPTSVILTL Pucgr2 KFISSRAFEIGAMERSMKL-ASGKRSF-QTLPRHLRRRAASHFVRRVPTKLRPKARFELSLKKHKTKTLLKR--QV-EKK-WLKTHIWHAKRTKMIDLWGFRLAKTPTEKCFRPTYRAA-RHGFTLHDLSYTHLNLTAIKQTLR-FIPGHRPYSLVGPATLLWRVLLQIHPSIKASVTEAIGLAVLVEELVE-LGCLELGGPRCLEMMREVETWLGFKPHVIPMGMIVGLVDDPRLKFRLAKCDFW--DKSQMQ--KKVNFKKLDRRRAMLDVPGSELPRIEE-DDQISILLVRVGWRMILPNNWTKAFFHSFIFSSARLVCL-DQFEAGRPSFPRDYPTLHGSEEARYWASKPPAKRVNFEGGDPFLLIGPLVGLVRVKLFIGLITTGSFRLTNGSSIGFGAISLRKLIPMIIYRNKNRARVEL Punst1 RFAEARAFEIRAMEDAMQS-ASTYRAW-QELPRHLRRRAASHDVRRVPARLREKARSEPKRGKANTEQLLKR--QR-DKT-WLETHIWHAKRMHMENMWGYRLAVTPTEKSYRPSHRAS-VHGSILHDASYSLIEMKGVALLLR-FTSGTKPLGLIAPATIIWRVWIRCHPAAFEDVFRALQTSVEILDLRDGVNVFEIMGPKASQVLKKFWSSLLQSAGSVPRGMVIGCVEDPRLDFTLAQSDIW--LSDTRKSLSQPKFKKIDKRKSENLVPGSALHPTPD-DNRVPILLIQRGWSLIVPAGWGMPFLSSLVYTGTRVGGQ-REFEAGMAYYPRDYPPTHEKAERDRWERTPPAKRVNYGTRSPWLLRGVTTALVGVKIIIGYVTAGNFSLSRGKGHAVGCVALTRLLKLYEIRDRNSAHIEL Rhior3 ---MARISEINSMQSAIKK-ALNELAF-QSLPRGLRRRTASHNLNRLPARLRAKAAKEKVRKIKRVDEYLRR--Q------------------------------------------------SKAHDASYACVELKGI------------PTKLICPISFLWKLWLWIHPSAYHEALQFIQQSVEINDLRQEILRFELIGPRSTALLNKLWKDLLRSSCSLSPGSVIGLVNDPRL-------------NETRKSLIEKKITELNQRRENNLVPGTKLEPTPE-DGQIPLLLFQRGWTLILPRGWGMAFWKSLIFAGARVAGF-EDFETGHSYFPHDFPGTVRKEAEEIWKKKPPAKRINFGIEHPFLLHGAPLTLAKIRLHKKKI--------LLLNYYTRYPTIF-LQSHSI------AMVLV Rhoto1 KFAQARVFEITAMQRAMKS-AGTQRAF-QSLPRHLRRRAASHNIRRLPSRLRERAKAEGRHRQ-KAELFRQR--QQ-NKL-WLETHVWHAKRMHMTEIWGHRLAETPTAKAFRSSYRAS-HHGALVHDASYQYFQLDGLERILR-FSSGSRPNGLLGPATFIWRLLVRVHPAVARHAASSVQHALR--RYEKGFLTFEVTGRRATEVVKAAWRKLKAGPGGVPEGMVFGLVYDPRLSFPIASAPFW--DIKHRASIHTPRFKKLDARRAEELIPGTRLAPLAQ-DDRIPVLLSQRGWTLTVPAGWGMPFWSSLVYSTPRVAGI-REYEAGAPRFPEDYVGSREADEQGYWERRPPAKRPNYGTRSPW-----RLAMVRVRLVIGRITTGQFCLSQGHGDSIAVVSLYRLLAMAKCRNRDSATVEL Rozal11 EFVKARAWEIHNLNNALSE-NSTKMIF-QTLPKHMRRRAASHNPKRIPKNFRPKNSKNNRRQRRKREFFANR--QN-DKK-WLETHIWHAKRFHMANLWGYRVPLHPNDKGRRAIYRDS-LHRSVMIDLSYKCFTLN------R---SRKHPTSMICPLMFQW-LSLWVHPSSHDALCEIFVAN------NDKLSLFEFHGPLTLPILQLEWTHL-QSPE------TIHLVEDPRLKYKTEDSGLF--NQDYLKALENGKLKEINARKSKLEIPGSKLENDPAIDPSIPIMLSYN---LVLPKCYSTEFLRLFHFAGVRIAGL-REYESEKPFFPDDYLTTIITETEMEYNKKPPAKRPNFNTLAPFILQGAFISIVAVSVMIGFTTTGSYSFSKGKSFAIGYVSSLKFVEYCRIKHPNWAKLSL Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------MERVP----------SRRNRRRNREYAKR--SA-HKT-WLHTHIWHTKRFKMEALWGWRIPVHANEKSVRANYRWVKGAHCTMADMSYSCFQLTGVRAALK-ATAGA-LIGVVSVIATPWAVWVWAHPSIAVDVHTAITTAVKVEDMSGELCRFRLVGGASHALLTAVWQSLMRDPSQLSAGAALCLVWDPRLRSTTSTASLW--SPTARAAINTSKLPQLDRRRSR----GGDLPPTTK-DSLLPLLLIQRGWDVVLPSAWAREVWHCLVHAGAKTCGL-RDTEQGMLGFPFDFVGT----------------RAQH-------------AGCVTEVVAGGLTSGGFCHSRAREYGLGFVTVAALGECIRSKHADTVHLRV Schco3 KFAEARAFEIDAMHNAMQN-HSAQRAW-QALPRHLRRRAASHDPRRVPTRLRERAKAEVKKG---AKEFAKR--QR-DKS-WLETHVWHAKRMIMMNMWGYRLAVKPTEKSFRPSHRAA-MHGSILHDASYGPIEVSGLKLALR-FADGSRPLALVSPASIIWQLWLRCHADAFQWVFQILQRSVEIADLRGEVNIFEIMGPQANQVLDQFWASLLQTSGAVPRGMIVGFVDDPRLRFALAASTIW--DPDVRKKLSVPRYTQLDERRAKNLVPGTPLNTLRL-DNRVPVLLIQRGWTLIFPAGWGMAFLPSLVHTGTRVAGQ-REFEAGVPHFPQDVPGDRSMEEHARWERTPPSKRPNWGTASMWLLRGPETALIQVRVNIGFVTTGNYSLARGEGFGFGSIALTALLKLEE------MFS-- Schpo1 KFIESRSFEITALQDAMKR-SSAQRAF-QALPRCLRRRAASHNIKRIPKGLRDRALYEAKSGETKRGKFAGR--QL-RKV-WLPTHLWVCKRAHMINAWGYAIPEKPTEKSYRPTHRAAFRKDAIAFDMSYPLFCISGLKEKF--FLNSSRIHELICPCFLQWNLVIRLHPSAFLQAWNYLSGIIAMHDWRLDLASFDIHGPDSNIMLGKVWQSIYSSAC-LPMGASISVLVNTRCDKANQYSTYW--ERQEIPSFAVFENKNTHEKKSS--------------KEVIPVYITYRGLTVILPWDYAKFVWRKMMYQGIRFGGL-ENFEKRMPFFPIDYPDTRKKRNEDSWKRRPPAKRVNYEIGNPF--------LVRVQVIIGFVTTGNFNLNAGKPSGIANVLAKTIKN---IRNVGCAQWKF Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar EFTAARSAEIHSLVNASKA------------PRNTRRRAVSHNPRQ-----RQVSKQQCRRARRRTNERVRR----------LETHLWHAKRMHMSTKWGCYIADTNAHRGERAAQKDV-LAHCAVHDASYRCLEVGGLGRLFAAYSNTLA-------VSFAWKVWLWIHPRDYDELYSVIKEALVVTDWSAEVGRISLYGPNAAQILQALMKTL-----SKTDQSITPLVVDPRFYRALVESSLF--DDACRRKASECKVSDFNAARSRAIAKKGGLQTDIY-AETLPVLVVKRGFDLIYPSGYGMPFWMALIYSGAHAFGQ---LE---------------------------------CVLTPFRI-----DVVVVAVVMGVVAMGGYSYLRACGSGIAYISLERLETWGVVGEGGGAYVSV Spipu1 EFAEARAFEISALQKALEN-AGVQRVF-QTVPRYMRRRAASHNVKRLPQRLREKALAQPKRRRTKTQDFARR--QM-GKR-WLETHVWHAKRMKMVELWGCKLAEHPNDKSSRASFRAA-KNQCLVHDASYQVIEISGLQILLR-YIEGSRPKSAIAPATFLWRLWLWLHPAVYEHVHDLLLQVVTICSLYDELVRFELTGPRTHAVLRQLWAKLLRSSASLPPGVAIGLIHDPRLSFVA-DSSIW--DPAIRKASLIGKATELNARRAQALIPGTALQPLPH-DVHVPILLLQRGWDLVLPKGWAMDVWKSLVFAGVRVAGL-RDFEAGLPCFPYDFPETVRHEEEEAWKRTPQGKKPNYGVKSPFVINSPRLMLVRVRIIVGYITTGRFSFAQGHGQALGCCKLSGLHRIVQVRGITGAIFNL Sporo1 ----------------------------------------------------------ARHRRVRAEMFKKR--QR-TKL-WLGTHVWHAKRMHMIDIWGHRLAEKPTEKAYRSSYRAA-FHGAMVHDASYQYFQLDGIRSLFR-YATGARPLGLIGPATFIWRVLVRVHPTIAKPAVEAFEEALEITRYEEEFVTFEVTGRRAAQVIKEAWKKLEAGPGSVPEGMIFGFVYDPRLSFDIAKVEFW--SAWNRKKIATPRFKKLDARRSQNLVPGTPLRPLAQ-DDRIPILLSQRMFTLTIPAGWSMPFWTSLVHSSPRVAGL-REYEAGLPTFPQDYPSTREADERGYWERRPPAKRPNFGTESPW--HLDRVALVRVRIVTGRITTGTFSLARGQGYGIGVVSFPRYLQMVKFRNRDGATLSI Stehi1 KFTEARAFEIGAMQRAMKN-ASTHRAW-QELPRKLRRRAASHDVRRVPARLRGKARAEPKLGKARADIFERR--QK-DKK-WLESHLWHAKRMHMENMWGYRLAIQPTEKSFRPSHRAS-VHDSILHDASYALIELKGLKSLLR-YITGARPFGFIGPVVVMWRVWVRCHPSIFTDVHVALKLAVEVTDLCDSVNVFEIMGPKSSQIIKEFWKALLQSPGSVPKNMTIGFIHDPRLNFSLSTSELW--NLDKRKNLQIPRFKKLDARRSQNAVPGTPLNPTSS-DSKIPIIVIQRGWTIMFPRGWSIPFLTSLVYTGTRVSGQ-REFESSVPFFPRDFPFSRATEEKERWERKPKAKRASWGTRSAWLLQGSEVALVQIRLIIGYVTSGNYSLSRGEAFAIGCIPLVKLLELKQVRDRGEAWVEV Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr QFAAVRLAEINAMLEANTI---GQRAF-QKLPRYLRRRTASHNVKRLPKRLRFAAQLEPSRKRRRPNSIVDYT-RRAGKAFWLETHVWHAKRMHMATIWGVRMALTSTDKGARYVVKAA-ATEALVRDISFAAISFAS--AAAA-AMSGER--GCLGPTTGVW-LWLTLHPALAADATDVLASAVEHL-LPGELCRFTLFGPRSNRIL------LLHSPDSLPARAVLTAITDPRLL-KSG-------------------------------LP------------PRPAM----GFDLVVPRGYGKAFMLAMVYAGARAIGH-DDTEAGAAAFPFDYVGSQAAAAEAHWRARPPSKRVNFGSPAPFFMDVKCPVIYC-----------------------------SLQEGAS----------- Treme1 KFAETRALEILALQNAMKS-SNNSRVF-QSLPRHLRRRAASHNPRRVPKRLRSKAASERARAKGKTEELLRR--QN-NKT-WLPTHIYHAKRFHMSTLWGHRIPLTPTLKSFRPAYRAS-RRRATLQDVSFGIIEISGLITLLK-YETGARPEGLIGPVGMVWALWIRAHPAIFDQLWGALRVA----DKRGEVGAFEIMGPLAGQVLKQFLRQLVGSSGEVPEGMVVGLVDDPRLSFSLASTSLW--N----AIPSKPRFKKLDRRRQLQSTPGTRLIPTGE-DDKIPVTITQRGFTLIFPSAFSMAFLLSFIYTNVKLVGL-AERECGIPHFPEHWGGTKAKEEAEWWSRRPPGKRPEWGIECPFLTPH--LTMLHVKVIIGWVLSGNFSLARGKGWGIGMISLKSYVNAVKVRNKDGAYLSL Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 SMQWRRLLKTQGMSDTFLHGALNQLAF-QSLPRGLRRRAASHNIKRIPVKLREKAKSESRRKKRRVEEYLRR--QG-NKR-WLETHTWHAKRMHMKDMWGYRLAEFPNEKSIRATYRAS-SHLSILHDASYACLELKGISRLLR-YNKGHRPQNAICPITFLWQLWLWIHPAAFEEAWTCLKDAVVITDLRDEILMFQLTGPRSTALLNKVWSSFLRSSASLPAGAVLGIVQDPRLKFDVAFSDLW--NEEIREELRKNKIPELNVRRSKNLLPGTKLLLTDD-DARIPIILAQRGWNIILPKGWGVSFWKSLVFAGCRTSGL-REFESGIACYPQDCPDTEKLAAEKSWKRKPPAKRLNFGIADPFIVRSNQVALVCIRILIGYVTTGQYSYCLGKGMAIGNITLDGLVKLHTVKGVQSGIIEV Ustma22 SLVSSRAFQIQSFLRSIKS-ATTTRAW-QLLPRHARRRAASHNLLRLPSRLRSKALAEPSHGIIRRKKLAERA-SHPQRR-WLETHLWHAKRFRMTTRWGFVLAETTMMKSHRASWRSA-KEFVTVHDASYAAHDASSDVELLS-TATGED--AALAPVRIVLLALIFTHPAADLHMRRALKAAVAINPMKQGFNIFELIGPRAASLL-------LRQLLNKQHGEMTAMVNDPRLSYSSQESSFW-------MGADPPRFSKIDSRRALNIIPGARLKPDTR-DNIVPVVLIRDRFTLIVPRGWGLAFFMSLVATGARVLGQ-HQAKADMLSYPHNWLGTAAVVRQDTWGRRPKGKRTEYGVARPYLVASAASAMVALKLAVGTVLDGDYSLGNGKGFGIGAITLRAWLQLEEMREPGTVTASL Walse1 DHVKARQFEIKALFKAIDS-ASSSRAF-QTLPRHLRRRAASHNPKRVPFRLREKALAEKKQQ--STVNLQKR--QL-NKS-WLETHIWHAKRMKMVNIWGHRLAKHPTEKSFRPSVRAS-RQGCIVHDASYALVQIDGILSLLR-YIFGTRPTEIISPISLIWHIWLRCHPSAFKTVYESLNEALTISDLRGQVNTFEMYGPQSSQVLRIAWQKILTTPAHLPTGFVAGFIDDPRLNYTLAQSGIF--SKAEREKVSKPRYKKIDSRRSKAQ-PGKPLAATPN-DDVIPILVIQKGYTLIVPAGWGMQIWSSLIHTDSRVGGI-EQVQVGASHFPESACPTRIEDVEERVSRKPKGKRPHYLPLLPFFMTDELVALVQATLTCGRIATSTFAMNEGKAVAIANMQAVVYFKLYSVQDNDDYRLHC Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3259.fasta_al_trimmed; alignment length = 1617] Allma1 MQGFAEKQELMVFQWLSLAADLESAPESIIKAEQVQLECRLQLF-TS-RPTRAIRRLIAACYISLYVRGESRAFDLLVSLQATL--NSNFKNLCVHVLGKLTERFGANFLSIFAETVHVLQKLLKSSSTLRLEALDALTRAVAPRGL--TDVQLKECLKLFRT-GLTDRSMAVRQGSADCISCLDFE-AFLLK--GFEGSNYEA-RIAM--ARAIANVLAAPIK-KKKGKKDEEMLSLLQTPFLRH-ARESRVGVAE-AYMALLQALGPSYVNYEAIVAHLFGDVLVSIKELVILRR-LG-QSMSETAQLNAIKHLYLARW-PA-MPETVPNKWVLGAVLAEMGDMFDLSGVDSVLEALLKIVGHPSAVQAAGAFCLMMTLNSPALYHVFNTLHKDLPSLSVAMAP--DLFRKYIGYSQAVATLLTIVNRVPLHVPSGLST-HVFSLASNLLKTS--SKDPKVSLTINEVAWNLISGLMTVGSATV--KGHLSQCLLLWKDAFPKS-QSS--------SGDEMLHAKEGALKSVCTFLVHNQ--ILNPDIKKRLSVLIGNVVQLTLGSPNVATTKAFP--DALFRKRLFDCIALLFDSYHSQLVKATGDVFAAMPVNAPGPL--FWQCA--EYGVTTL---------RDPGFPIQGSLEYDLINSAITLYGTLFQEAFLENYVRIL--KQKQERPGRKTALLVNVLTALQVCSSTMSALAAKSILEIAQHGNTAVRWVAAHVIGKVAELAAAGSAVASLSQYLVSQIVENRDPDTRAGGALALVMVHVYT---HS-SVNIKTTMGVLHTLCSDTHAGVAQWASLALSMLIEARSSDVYPYITPTLSVVCRQIM------------------VFV-GRIIYGCVETLGPELQVSDKLRDLICQFTEYDWEGLEEC-AEAWRTVSHILLMAPYAMAL-QTLLSTDHTTMRRAVLRCLC-QMIQRNPDLTLANTVD-LEQSLIRLAQDEPVL---VQKSLASLVENAT--QPSKWIDICRSLLQAAQAGPEDDSEELWSSQLTAIQSLRQVIHFLATGKNKEYHVNMVLAKSQ--RLGDLIRVAFTAST-AL-TQQVRAEGLGLLEDVLDHFSTTKDPDYEGHMLLEQYQAQFSSALTPAFQSDSYPEIVATASHVCARYIGSGITEELFTLSRIIKLLTQALDMIRASS----------HQSQHAT--IMISLAVLSAWAELKRTSDQRRVLAEIVEPQLLAPMWLTCLFEYAVIKLDPDSYALNTRDIVLPMYHKCWISILAAV--TSLLNSDVPGIQLSKHGAVESK------ILVLLGLAFEPLVSLRT----ETVTIQIDALHALVVPRH-IPT---LHKALIKELLTMVDRLLQTEALAFLTLVDQVNRLLFGAIAMPHLLALLTLGKLAAVHPASVP----IALHVLAAAYESPMAGRMTVLLKGVLELVMSFVAALLVDAATNDGAGDIDARNCLLASTVSLTSL-----HDKPFVARFTVVLIE----LSLIAFQCAKSLIQLGKKLVTLVPHLI-----NEWVATLVLSALIGLLVR--IVQGLLAIASVHTAAFKSMVAALPPSRQALEAGLRAHQGAHAA--SIQLKM Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MSSSEEQQDLYLLTFTSLVQYISDLDSASVSLQQKSLKKELFKI-LTPTITRVIRNNLGRSFGAILGKGDRGLFETVTDLLAILN-AG--KNAAAHCLGEVFAVAGESVFAQSGTVASGLLKLLKSSSNLRGSTFAILRKVVAGVPV--DEGTARDIWKQARNAATSDKSTFVQVHACRCLEQLDFD-HLKWK--VIDSNVAPV-RHAA--AACLAQALVKKMKRKKPAPRPPDLLRQLSTQYMKT-SNRARAGIAA-CYKYVLRSLGDKLVRYGQIANHLLFELLLMTRRFVILEETVGRETLRENSQLNAAKWLILKDY-PQVLQEREPSKYTLASTLSALSSLISLGSAEACREALLQVLPHPSTVQIHAAHCLRFVLACPHQLICLNSLSREIGQLST------QAPRRCVGYANGLSAMLSTSRLQPLYGSVDVFS-RVFTQATDLLKTSG-KSELRAASTQVQVAWILIGGLMPLGPSFV--KIHLSQLMLLWKNALPKH-LGKD---NIRGYLEFLAHVRECALGSLLVFMDFNS--LITADGARRIAAMLQNTIEFLDDRQKSVSQRLQPSLTTMVRRRVLQCFSKLDVISQTTLLSLSISSFASSIAAATAQFETLWELCDNGFGVTGLSGKQDNENGVDLSDPICQASEHDVVNAAIELFAVAIQESTMEQIATFLSSQSLQRNPGRKAAMIVNIAVALLHALKIA-PVTEKVLQELLQKFVVIVRTIGAEALGRLCDGAGN-TLMTTQVNWLVDTIVDNREPNARAGCAAALGCIHAQVGGMAA-GLHLKTIVGVLMSLCNDPHPVVHFWALGGLERVANSAGLTFSPFVSSALGMLAQLYNEEAA-SLATSNIETFLTPVVI-SRCVDSLINVLGPDLQDITKTRNLILTLLRQLEDNPALV-TESSKCLDHMSLYAPFVTRL-QNELSAGNPLMRDVAIRALS-NLMKRDATSVLRAATPDLEEQIWLAYDDTPDN-LVLKNMILDWLQHTALTETEQWIQRCQNTLTSAVKTADDEVAGFWQTRNFVMSCLSQLLATVQEA---------ILPDQ---KVGDIVRMAFSAST-AN-VVELRVWGLKIIDQVLKMFGKTPDPDFAEASLLEQYQAQIGSALTPAFAADSSPELASEAINVSATFIATGIVTNVERMGRILKVLVLGLENFSNPDTTE--FGDLKGLNSNAK--VMVKMALFAAWARLQIASIDQDYLNEVVQPYLLTPLWLSSLQEYARLRFEPDIYAALNRETLLKFYQDSWLSLVDAI--AGLVEKDIDFVFDALDGKTTEPRDEPVAFFVLFGLAFEALV----TPS-QRL---LQALKRILRPVISGNA--IYQDAIFSETMDTFDRLALTEIVEIANLSLDLTRSIILVLALPNLGVLSSLVQVASIFPSIIRDLNACILHIFTTILATEVVPQALPTFKHFIHQLRGCLTRFLLTIAQ-RRESESSAKNTLLAITILLTT-------GGHILPAIPRVLLDCLQDLANVAAGCIRSILLTS--AKYLLPRLI-AFLVTVIARTLAFSIVMSALLARATAAHLLELARADQATFRALVASMKPQKGLLEEILRSSDAGRAE-TSIALRL Aurde31 MATAEENAEIYVLHWLSADKAINDLGADVLKPAQASLETTLIKI-ATPVPGRSVRNLVGRCLVALYLKAETRMFDTMQTFFK-A--ASELKPTALYCMGEVMRVHGAQIMSLATDIVLVCLRIAKASANLRYNALVCLRKVLASRAL--TDSTTKDVLKQSRG-YLSDKASPIQRAAAEVLIALDVE-SIVVR--SLDGADQQT-RRSL--ARLAGHMLAEPPKKK-----EHEMLLILSAQFNKT-TRKARIGIFD-FYATLLLTLGPSWVNYAIVVRHFFTEIVLSIRKLVLLRDLIGVRMLSEQGQIGAVRELYVKKW-PAIMPGQAPNPLVLVIALREIAGLLQLGSADALADPLLEILSHPSSTRVAAAWALRFCHAAPRRLTALEALQNNIAALTSAAAP-ADIDKRTLGHAYGLAALFSVIPEKPLYVSYDLSA-KVLDVAIQLLKRSG-EHDIKIAGVEVEVAWTCISSLMCLGPNFV--RAHLPQLMVLWRNALPKP-TSKD-IASNRSDAEFLLHVRECALGAIFCFLQNNA-ALITLDVARRVSSLLNHALLFANAAQSSEASAPSISVEAMLRRRIYQCYSALTLSTTEALLQSAVTLFAAAIATSSGTFSSVWLSADGGFGVTKLADTSGQDSGRDTIEPVLGSFEHDVIDGAIELFSQLLCSKTIAQLIDGCRSPKLERNVGRKTAVFVNATVALMLALRVASSHIAATLTDLLKGAIIVLRNAGSEALGRLAGLAGT-AYLSSQITSLVDQVVNNRDPHGRAGCALTFGAIYSHVGVLAA-GPLLKTTVNVLMSLGNDPHPLVHFWALSALSQVTNAASLSYAPFINSTIGMLVKLYSPEGG-SSNNANIADLPTYQVI-CRIIDAVIGVTGPELLESSHKRNLILNLVTEHEDDAGIG-VEAIRCIEHFLIFAPLIQRL-RSNLSSTRRPLKVASINALY-RLVQRDALLMSKVGGDKLVEDLFGMLDDDSTI-EGVRNVITSWLTQTAAQNPSAWIDLCQRIMTASQQAVDDEVESLWRTQLFALQCLHEICRITVASGIRE-HFDIPFAKRRGLRVPDLIRMAFTASA-AH-VPEIRLEGLVVLRDVIEIFAKSPDPDYEDALFLEQHQAPITAALTPAFGQDSTPEVLASAVQVCAVFVGSGVVKDISRMGRILKLLTSALEQSKGFGTLS--IGDMGQLSPNAS--VMLRISTLTAWAELQISSPLQSYLHDVLKPHRLSTLWIASLRDYASIRVDSEVYFGLGREVLLPYYTKSWPRILKAV--SISMKSQDPTILAAMDGL-DGPKDEPTAFFPVFGLVFEALSSQSS-ADSMEMTITLDALKSLVRPEYCGSA--VLESAIFDELIGLSYRLALTELVEAISLAVSCLRICSFVLRVPTSRAFTAFATISALYAPARQNLRAVGATLYSAFLKDDLVGPTLPALKALLEVVHGLLSACLMEEMR-GREGPIPTKNNMLAAVLILTTVPIGVKLSNAVLELISQRMAE-ISEISLTAAHCAKTLINGATAVRFLVPGMI-TYIAEETLKAFALAVLLPVQVMLLAVAQLLSFATTTPVAFKEATAKLHAIREKLETSVRQAISA--G-QQISLRS Batde5 SETSSERQELLLFQWLSLEKDLGSTTKDILKPHQPNLEKLLLKF-LGIKPSRPIRELIARTFVLIYHKGDQRLFDTLAAIQNLL---SNKKSALIHCIGVLTESHGVKVMSLFAETAIILTKSFKSAKDTRYEIIKAISSSLAGKGA--TKILLKEFVRFAKL-GITDKLPIIRMASAELYTAIEME-AFVVK--SLDGSNYTC-RRAF--CTLISALFENFAKIKSTLKNEQEIFNIISSQFIKS-TREARVGVME-ATAAFLNRMGPEFVNHPTILKSIVDTV-TFVFECGLMRNVVG-KMLTERGQTNCVREIYITRW-PAVLPTDAPSDQALTFVLYELSALIDLGQSEQLVQSLFSLLPHPSTVKVALAWTFRICVALPENLRLVGLLQKDVGLLTP------DVVDKIQGYANVVAAVTSVISLHPLYAVYEDAA-TIFGFSTQLIRAIGSSRNQRVCVCQVQAAWTLIGSLMSLGPNFV--KVHLSQLLLLWKAVFPKS-QPKD---LNRSELEFQFVSRESALAALYSFFVYNAKDLVTSDVAKRIVVCLNNTLNFLST---------IPLEECQLRRRLFQCYSAIYDISYVQLMKATIDTFASVFSTSLNYTISVAAESEADRGIS-----------QDTDVRVFGSCDNDMVDAAIELFAFLFQEIFIESIIKSVTVQAGKVTPARKDAAQINSLISIIGALKYISGKVSVAIRDLADPFLRILRATASEILGRLARVVGTATFVGPLIQSLVDQVVNNRDPESRAGAALALGSIHSFVGGMAA-FSHLNTVVGILHSLSCDPHPLVHTWALHSLWLTIESAGLMYGPFVNSTLTLVVKLFMISAP-AANGSGSDNAQVGPAF-GRILHALVGVIGPELQMSTSLREICFCLYEQNNDDPFVV-VEAIRCIQNFILFARLIPFL-QVQLSGDYRAIRKASVTCLY-QLIQHDPETVLCATIGNLEEQLFALLDDVMVR-DEIKDILMALLRHVAPDHPSRWLDLCKTILIGKAPVSDDEDDILWRTQTFALTCLRTVINVVLATESSE-HLDMATARSVRKRLVDLIRMAFNSST-SN-INDLRLGGLFLLHDVLEKYSDSMDPDFEGHMLLEQYQAQIIAALAPAFANESSPEIISTACGVCSFFISTSQN--ISAMTRPLKLLGGLLDNF---SNES--YVNS---LPSSNAFVMLKISVLKAWAELHSSSVEQPDLVPAIQPYLLVKLWLNMLQDYAKLTIDADAYMSATRQITLPFYQQSWVLVIKSL--TDLMRDKTPATLKILDSK-QMS------LCMLLGLCVEAISGN-SARAAENMRVALGSIKKLLQIYSFENM--TLPQSIYLELLSVFNRHVLNSLVDTLQMIIDVVLVLFHIIAIPTLNAFGALLLLAQCSSLLQKSLIFLIFSILTTIVSTDVAPKSIVLIKPLLECLCATVSNMLFSQKT-QKTLEETIQNALLVVILILTIQPASSHYLANQVK-LVELLLNGSNIIALLATQYIRTLILLSCRLRLLLPISA-RYIYEESMKTLALAILMPLYLRSMAAKTLLQCASQCQSQFKLVLQTLEDQKAKLEWSLKSMMDARQS-GKIQLKN Botbo1 ------------MHRCNTQ--------DVLKSSQSQLEATLLKA-ITPPPGRPIRNLVARCYISLFTRGETKVFDVIQALLK-V--AGDPKSASFYCLGEIMEGFGSQALSFMGEIVNCSIKVFRTTSNLRCQALSALRKSLGARAI--QDYAARDMFKHMKN-GLSDKALPIQRAVADVLLAMDVE-AILVK--ALDSADHPT-RHTL--SVLVGNVLADTSKKKTATE--AEMLNHLAAPFNRS-SRQTRIGIIE-IYSTLFTVLGSNFVNYSLIVRHFTSDIVLFVRKLVILRDLIGARMLSEQGQIAAIKELYLRKW-PALLPGSAPSEFVLAVVLRETSGLLQLGSSESLSDPLVQLLSHSNSTRIGAAWCLRFCSSTPLRLTVLEMLQNEITAFSAPTAP-SDIASRALGHTYGLAALFSVFPERPLYVAFDISA-KVLDTAIQLLKHAG-EHDLSMAEIEVEIAWTSIASLMTLGPNFV--RTHLSQLLVLWRNALPKP-TSRD-ATAGRSPTEFLLHVRQCALGAVLSFLKHNSPTLITLDVARRLTTLLTNALSFVNSTDTLEQEELANT-EAMLRRRVYQCFSSLTEQMQSTLLQSVTTLFAASIATSAGTVASVWQSADEGYGVTSL---EEKRARRDLVEPVIGSCEHDVVDAAIELFSVLLALKIISQLVEMVRSPKLERNSGRKSAVFINATAALLLSLRVGSPQISAVLSDFLKDAILTLRFAGSEALGRLASLAGT-SFLTSQIKFLVDQVVNNRDPSGRAGCALAFGAIYTQVGGLAA-GPLLKTTVNVLMSLGNDPHPVVHFWALNALAQVINAASLSYSPFISSTMVMLFKLYMPEGG-SISNSNLRDLPVYQVL-CQIIDAVIGVLGPELQDSTRTRTLVLDLVQQHETDEGIC-VEAIKCIQHILIFGGLVRLC-RTHLYSPRRPLKMASINALY-QLVQRDAFAVSKLGGDTLVQELFGMLDNDPGI-EGVRNVISNWLQQTAIHNPSAWIDLCQVIMTATQQAVDDEAESLWRTQLFALQCLHSICTIVATSGRRE-HLDIPFAKQQKLRVPDLIRMAFTASA-AY-VTEIRLQGLILLQDIIQIFAQSPDPDYDDILLLEQHQAPITAALTPAFSADSTPEILASAVEACAIFVGCGVVKDVGRMGRILKLLTTALEQSKETGTLT--IGEVGDLSPNAS--VMLRVSILTAWAELEAASPMHAYLKAVLRPHRLASLWIATLRDYASIRADSELYAGLGREVLLPYYSSSWIKILKAI--ATAMDQNDTHILAAMDGT-ETARDEPTSFFVLFGLIYEALGPTASGPNRQNA-ITLEALKSLVASKYSGKA--LLEPTVFDEFCALCYRLAMTELIPVLAFATSCLRVCAYILRIPSSLGFDGFFVIGQSFGVSFREIRAIAISLYTELLKDDLAGPTLPALKTILTLVHGFLSACLIDEMR-GRQGPVAIKNNMLATVLVLTVLPTSVKLGRAVVDLISHELTE-LAEVSLTAAHCAKTLVLAALSVGQLLPGMI-TYVSEEILKALVLSILLPLNILLLAVSNLLQFANSAPAAFKEATSKLDQLRSTLEASLRQALA---T-TQISLRT Botci1 MSSTAEQQDLYLLNFVSLTRHVEGLEPDDCTAQQLYLKKELFQI-LNPPPTRVIRNNLGRCFAHVLGEGDRKLFETINDLVTIIS-NGKTKTAAVYCLGDVFASAGDSAIGLHSLACSAILKLLKSAQNLRAAIFKAASKIVVATSM--DDTIAKDIWKQARSYASSEKSALVQIAACKCLRSLDFE-SLKFK--TIDSPSALV-RQAA--AECLAEALVKRTNTKRSSVIAQEILKVLSNQYIKT-TNRARAGIAV-CYSRIFKSMSERTVMYMQIVDHLTVELLLSTRKFVILEDVVGHSILGESGQLDAAKSLILKNY-PQVIKEREPSKHTLIATLSALASLITLGSAEGCRDGLLQVLQHPSTVQIYTSYCLRFTLACPQQLICMNSVNRELNLLNT------NSPRRCVGYANGLSAMISTANLQPLYGSVDVNS-RVLSLATNLLKSSS-KSELRVSSTQIQVAWILIGGLMSLGPNFV--KIHLSQLLLLWKNALPKP-LAKD---NTRSFLEFLTHVRECALGSILAFLQFNS--LLTADVSKRIAAMLTNTSAFLKSSKKLSTQRLTPSLDLMVQRRVLQCYARLEALLQSNLLTLAVSFFATSIASSAGNFETVWDVGDNGFGVTGLSSEQENGSQETGSDPICSSLEHDVVNIAIRLFAIAFQESILEQIATFLSTGALQRDPGRKAAINVNIATALFSALKVANPAVEKLMQEILRSFVVYVRNIGYESLARQCNISGN-TYTNLEIKHLIDTIVSNREPSARAGCAMALGCIHSQVGGMAA-GFHLKTILGILMSLCNDPHPTVHIWALESLSRVAESAGLTFSGYVSSTLGMLCQLYVEEIS-SLATSNLEELSTTAVI-TRCIDSLVNVLGPDLQDMTKARDLILTMVGQAEENILVL-AGSLKCQEHLALYAPYVVLL-QKDLKSDISLLRDIAIDGLY-NLMKRNSEDVVKAAETGFEDQLWLALDSDPAH-DGIRNVIRNWLQQSCLTETPRWLQRCQTVLAVSAKVSDEEVAGFWQVRTFAMSCLGEIFTLVSKD---------LTANG---RVADVIRMAFSAST-SN-VVELRVWGLKIIDAVLKMFGHTPDPDFAEAPLLEQYQAQISSALTPAFAADSSPELASEAVNVCAAFIATGIVTDVDRMGRILKTLVTALENFSESEVAS--IGDLKGLSSNAQ--VMVKMAVFSAWAELQVASTEQKYLVDVLKPYILTPLWLASLREFARLRFEPDIYSALNRETLLRFYQDSWLKLVDAI--ASLIEQDSEFVFNALDGK-EADRDEPVAFFVLFGIAFEALVAKPGASKGQTL---LQALKKILHPSVSGHA--IYREAIFSETMDLLDRLVLTEIVQIASLCISLTRIIVLVLALPNLISLNALVDAAEVFPSIIKDLHACIIHIFATILGTVVVPQSLPILKRFITQLQGCLKRFLYMNAQ-KRETEVSVKNTLLASTLLLTS-------GTNHLSLVTRFLVDCLSDTAKVAANCIRSLLLTNP-ARYLLPLLI-TFSTALTLHAVAMSIVIPTLLKRATNARLLEMAAADPTAFRAVVGGMTAQKGFMEGVLVKGR------RTIALRM Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 MAALAERQELAAFQWLSLCSDLDTAPSDVIKANQPNLERRLGLF-LS-KPSRAIRRLIAGCYLGILSRGDSRAFDVLVSVQSNL--GASIKALNIHILGRLTERFGANYYSVLGETTHLMFKVLKSTSTLRNETLDALSRAFAGKGL--NDAQVKDALKLLKQ-GLTEKSMAVRQLSAECISGLDFD-SFLVR--AFEGSNYDA-RIAI--ARAIANILASPAKLKKSGTK--------RAPLLKH-ARESRIGIAE-AYVMLFQLLGASYVNYPTIVAHFVNDILVSIKEIVILRS-IG-QLQSETAQINAIKHIYGGRW-PA-LPQTVPNKWSLHALLAEIAGLLDVNGVESSMSTLLKLAGHPSLVQSSAALCVLLGINSPATFHLHAVLYKEMANISMATPT--ENLRKYIGYSLSVSALLAAAPKVPF------------------------------------------------GSNGV--KAQLSQLLLLWKDAFPKA-QSSG------GQGDDLLHGKEVALKALCALLLHNG--ILTPDLRKRLAVLVTNVIQLVLATPGLGTTKLSP--ECMFRKRLMDTVSLLFDSYHGQLVKAASDLFALQPVNSPGPL--FWQSA--EYASHTL---------RDPGFPVAGGSEFDLVNSAIGMFGLLFQEAYLDTYARYL--KQKQERPGKRIAMLVNVIQAMNTATAVMTPQATKSLLEIAHAGNCGVRLSSASIIGRVAELAAGNTASATIAQFLVSQIVDNRDPDVRAGAAMALVMLHVYT---QS-SSIIKTTVGVLHTLCTDLHPGVAGWATYALAHLMEARAAQVYPLVTPTLSVVCRQLM------------------QFV-GRVLFGCIDALGPELQVSDKIRELLTQFTEYEWDGLEEC-AEAWRAATHLLLMAPYAGVL-QALLGADHITLRRSVLQCLC-SMVQRGPELVLENTTD-LERTLVMLARAEPDL---VNKSLASLIESSI--NPFRWIELCRSLLSGGTA-VDDDGDEVWTSQFLALQTLRQLIRFLATGPNREYHVNLALARGT--RLGELIRVAFTAST-AL-SHTVRREGLALLEDVLDHFSVTEDPDFPGHRLLEQYQAQFSSALTPAFTAEADPEIVATASHVCARYIGSGITDDLLTLSRIIRLLTQALSMVQASSGTS--IGSTAGQSQHAQ--IMIALAVLGAWADIRRAAAGKPALAEVVGLQLLLPLWLSVLFEYAVVKQDMEVYALSSRDVVLPL---------------QTLETDS---LLTKHGSITTP------QLVIFGLAFEPLVSVRS----EDTTIVLEALQVLLSSQNLMKQ---VHPSIAKEILTMCDRLMQTEVLSLATLMSN-ESLTTSALA-----KLISILKHALDNPSS--------------------------------ELAVSLAATLIAESNL-----QID------------PSI-----FNSEVLARLAGLIVQ----LSIVTLQCARSLFQLAKRARVLLPHFI-----SECVATIVSSVLIGVLVRFPAVQGIMAMAKVCPQAFRDVVSQMPQSRTALEAALRG---------SVEV-- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MNGQAEQQDLYLLTFSSLARHVAALDGDGASAHQIYIKKEIFQI-VNPAPTRVIRNNLGRAIAGIFEKGDRKLFESINDSVNILN-TA-GKSAAAHCLGSIFEAAGDSAIQLSPLAVKTLLGLVKSAQNLRAALFKAVGKVFVSSHA--DELIARDAWKQARN-AGSDKSYIVQTAACYCLEQLDFD-KLQWK--IIDSPSSSV-RHAV--ASCISAALVTRSKTKRKSRKPESLLKLLATQYCKA-GNRARAGIAV-CYIKTIKGLGEHIIKYSDIARSLFVDVLLSTRKFVILEGVVGRGLLGESGQLHAVRFLILKDY-PQVLKEREPTKQTLIGALSTLSSLFSLGSADTCRDALIQVLQHPSTVQVTASACLRFVLACPLQLICMNSVNRELGLLAG------QSPRKCVGLANGLSAVLSTSTSQPLHGSVDVNS-RVLSQATSLLKSAS-NSDLRIGSTQIQVAWILIGGLMTLGPNFV--KIHLSQLLLLWKNALPKP-LNRD---NMRNYLEFLTHVRECALGSILTFLEFNS--ILTLDVTKRLAAMLQNTTLFLNTAKKTTSQRLSPALDLMVRRRVLQCYTKLEVLLQTNLLPFAIASFATAIASAAGTFESIWEVADNGFGVTGLPGEQEAHTHRHGPEPICGAREHDVVNAALQLFAICLQESILEQMTSFLSASSLQRDINRKTAMMVNIAYAVLSALKVAGAAVEKVMQDLLHLFIIFIRNLAGEALGRLCNSSGN-ALTTTEVNYLVDQIVANREPNARSGYAVALGCIHSQLGGMAA-GFHLKNILGILTSLGDDPHPVVHFWAMDSLSRVADSAGLSFSSYVTSTLGMLAHWYAEESA-SLPYSNIEDIPTPAVI-ARCVDSTINVLGPDLQDVAKARDLIMTLVGLGDADELIV-IESLRCQEHISLYAPYVKSL-QRSVESSSTQIRDMAIDGLH-NIMRRNTEEVMRAAEPGLEDQLWHVLDRDPEH-EVVRNIIRNWLHQTGLSDTATWVQRCHSVLEQKPKAGDEEVAGFWQVRTFGMDCLSELVAMVSKE---------AAFRE---RVADVVRIAFSAST-AG-VVQLRIRGLKIIDQVLKLFGKTPDPDFAEVTLLEQYQAQIGSALTPAFAADSSPELAAEAVNVCATFIATGIVTDVDRMGRILKLLVSALENFSESETAS--IGDLKGLSSNAQ--VMVKMAVFSAWAELQIASAEQTYLRDVLKPHILTPLWLASLREYARLRFEPDIYAALNRETLLKFYQDTWLNLVDAI--ASLIDEDSEFVFDALDGKTELSRDEPVAFFVLFGLAFEALAGRPGASKEQIL---LQALKKILRPSVSGHA--IYQEVVFSETMDMLDRLVLTEIVQITNLCIGLTKIMVLVLSIPGLEALSALVDAAQVFPSIIKDLHACILHIFASIVGTTVIPQALPIFKRFITQLRATLARFLLRHAQ-KREFDAAEKNTILTATILLSS-------ASSALTLIQRFVFDCLGTTSKVAAGCCRSLLLLPK-AKLLLPPTL-SFLATTLAQTLACKIIIPALLSRATATRLLEIAGADQQAFRTVVTGLTPQRSFMEGVLKSGQ------RKIALKM Coere1 -----GGRELYIFKWLSLEEYLETSAAEKTVSQQEYLEELLLEI-VTPRPSRVVRGLVAKSLARLYELGQMH-MDNVIAAIHIV--MQDKRSAGV-LFEALGQRAGFRLLSSFNDFLAIGLRIIRTSAEVRVEATKMLARLLGGGKT-ATEQQARDCLRTLRP-NLGHRSPLLVMVSAEALCCLDPE-TFVVP--LLANPVLPV-RRAL--GRLIAVIMASASVRDLRDSPTERVLGWLGVPFSRT-SRELRAGIAD-AYAALFDELGGQVVHYGVISGHLIAALAGTARAVSLLHR-VATLLPNED------ARMLWETWI--AHGTR-------AVALGEWRRLVALDWD--------AWLAHPFPVRVQAAAALG-------AWGRAAQLAAQLATRLQCAEP--GSERLCAGLALAISAVLET--TDAMHVPQDLGE-WIHALGVRLLNISG----NSTQQRQQTAGWTLLAGATAWGAEFA--QQRLPQWRRLWAMALPADGGFMT-ASMSRAHQLVLAALRQPEIGTQLSL--DTGELATGLRAAMQFADNALDA------ESRTG-QQSLRAAHVCLRWRLAECLAKLHSALAGTAMRLAE--LAFAVEHMSSAGSSTW-----EVGVTSL--------------EVVGDVESELVDAAVQLWGSVFQVAQLS------VAQRLNR-SHRHMAALTNAVCGLAYASRK------------------QLRAAAGVAIGQLAAAVSA-REANDVLRQLSGLAIRARDRFARAGAAVALGALYARAGALVARGNQLRDVTVLLHSLASDNDPIVHTWALRALTDAALSAGYMFAPYARDTLRMALKLMLPDSR-VLSGRSADT-DARAAL-GQLVGALQVVLGPELYVVRELRRALASVVPTPNARWETAVSYILSVQRQLLFTSALRPVLRARCILSERPILQRVAVTALE-SVLRLYGSQLFSATKQQSDSCLLCEI-------VWDAACLHNNILDCIDSESLLLVSDLQTLINISAQKADDDE---------------ALLSTVDAVPK-----DT--------LLPDMLRVGYLAASLADRLPKLGCLGLGLLQRLVDLFASVDDPKMPEDSVLVVYQAQLDSAL-----AATLPAVRRASMTLATSYLLAPRLVRRMDMLRLLRHLAP-ERKHVDKRVWR--LMQLHVVERL---------SILRVWARILIH------LKESLLLHLLVEMWLAAVRDAVVVEIDTRDSSLCPVDVGLGLVLGLDSADLRLL--RSSMALP--PIIDALGG---PSDDVPSK---------SALLML-CGCGTD-----IRDLIGVLDLQTSNSVD-LI---ML-----AKLRMSQSLL----TVFSVCCKSTSLLLRNTSLESPSAQLVVITALRVLARALEKLWFGMWSQSVASEAASELLSFFVNLVETANSMLAQQLNSDCGDKNLTPIL--ARLC-CGTTFVVHPV---VRQRFVELLTGCLIRLLEEQQMNFEQCN-----------------I-VSLARAALNALVLATVLMLLLAML-AESILCLATKCPILFKNIVR----AKRRLEIAIRFGAQNNST-AAI---- Conco1 MNSYNEIKNVSTLNDIEQLGKIYQLPGD--KSKVKEYEMQLLHL-IS-NPSILASNSFSRCFRYIITSSSYTVTDTLGKLLDAF--------TIIECIGLMLESKGSMMNSFVNDLCLLLFKNWRTSTELRLNILITLEKLTCGSSF--NENLCKDVYKMAKQ-TMSDKCNAYKEVAVKILLAMEIP----VK--YFDNSSYLF-RKNL--AAYIATMIAEKPKKKLGIQGSSEVLEVLSASYSKS-SQDSLSGIIA-TYICLFTKLGTTFINYSEIVKHLLTKLVLAARQRCIFQD-ITQNILSEQGQIHAVKTLIMTEWVHQTAKADQISTWGIICAVDEVGHLIVLGDADSVLDPLMMLLDHHGSIQISASWSLRFCISFPSVIRFTTWLNAKF--ISSEASQ-TSIIRQGVGYGYALGALLSATAINSHSVSDDFGS-LIYTLSSEILNKSTDPIVFQFYSSQVQVGWTLMSGLMCLGPNFV--RLYLPQIMLHFHAFIQKIPTEFN---FRSSQMEESVQSHEGALQALYLLISYNQNLITSSKIHKQVIKLLIQSSQFIEDSNFGE--------VHMIRKRIMQCFSILDDSLAPLLTKLSINTITESLVTWTEDIVTDWIKWLGGFSMTSC---------FDKSIPTFAAKEYDLSDVAASLFGLVFQSSALESLLKSLKPEKLQED----SRPLVNALFALLSALKTIGDKAITIAEELVQLGLTEIAELSANCISLLCKHSNK-SIATRQVKFYLDKILAESDSIVRSSSLLCISQIYNSVGSQLS-ATNISSILNVLFSLFQDPHPLVHLNAIQTLTSICNSTGFSFSSHISQSLQRLFQLLVPN---SKGYSNHGHFVLKQNC-GKALNTIISILGPDVATQSTIYVSIKTIMEENDPEELVA-IEYLKCIQLMIMFNFIVSYL-CIKMHSLEDQLQRIAANCLY-QLVQKDASAVLTYSGTGLISRLFFLLDQQPHL-EEVIAVLKVLISHSKETEYSQWFKVLHTVLTNIGSIIDEEFGSLWQTQLVALQIMNQFI-----------TIDS--------RFGDLIKLSFSAAT-AS-IDQIRLEGYLLLHRLILEYHTVPVPQMTDMMIIDEYQPQITAALAPAINGEFSAEVTSKAIEVAATYLIKGSF-EIKSAGRLIKLLVSSLEHIVSHTTTS--TNESDKFNAYST--IPVILAVQSAWCRIILHTTSKANFSSIYYPHLLSTVFYSTLKNFAYLKLDPSLHSLSNRSWILNEYSKHWILILKAT--SYLIDTDHTEFIKPL-------CSQPTNFWIVFGLCVENLSFHSNNSPQTSL---LSSLKSIFIPSIAGQY--FLENSIFFELLQIFERYKLTNIVLVLQIVNSVYSFYVGILSIPGINALEAITCMATK------SFYVISLHLFTFILLDKIIKP----LKSILTTAKEFMVKSLFTKIQ--------ARQCIMAATVSLLALSQET-LDKELVNCLSHCI------VSSNGLQCARLLVNRLHDCKITLFRIS-----DEFLSEGLFKLILEVFLKLS--SSIIEIAAKHPAEFRSAVQSLSPNQQKLKSVIQNTTEDEDDFSTIQLKE Conpu1 AKGSEDNGELYLFQWVSVEKALKAVHADEVNAKQQVIEATLLKV-VNPPPGRALRDLLVKCYVTLYTRGDTRLFDTFQTFIK-I--AGDVKATAYSALGALMLAFGSNHMSFMAELSVIVQKTLK-SSSIRYHALVSMRKALARKAL--PDNTAKDVIKQLKN-ALNDKALSVQRAAANALAIMDVE-STIVR--SGENADQLT-RQAL--AQLVGHLLAEPPKAG----GESEMLSQLSTHFLKT-SRKSRASIFD-FYVALIQKLGSEFANYSLIVSHFMTEIALFVRKAVILRELIAVRMLSEQGQIAAIQELYLKKW-PALMPGQSPSSLILTLALQEVSALLQLGNADAILDPLMNLLSHPSTVRINASWTLRFCHSTPLRLSVADLLRRDIESMQSLAAP-SDVDKRALGHAYGLAALVAIIPLHPLYVSFDAAT-DVLDTATQLLKRAS-EHDVRIAGAEVEIAWTLIAALNLLGPNFV--RPHLPQLLVLWRNALPKA-TSKD-AMN-RSPSEFLLHVRESALGAILCFLKHNA-TLLTLDVGRRVSSLLSNALAFSNSSQSIESEAPSL--EAALRRRIYQCFTALTESTQSSLLQSATTIFAAAIASSSGSFTSIWQVTDGAYGVTTV---DVDTNKNELIEPILGACEHDVVDEAIVLFSQLLTARVISGLVEALRSPKLEKSPGRKAAMTVNIMVAILQTLRLSNPQVTSVLAPFLKDILISLRMASSEALGRLANVAGT-AFLTNQTKTLVDHVVNKRDPQGRAGCALAFGAIYSHVGGLAA-GPLLKTTVNILMSLSNDPHPLVHFWSLVALARVVHAANLAFSPFISATLTLMLKIYLTEGG-TLNNANMSELQASPVV-CRIVDAIITVLGPDMHESERTRTLILDLVNGVDLDEMVS-IEAIKCIQHLLMFSPVVKYF-RSHLISSRRPLKRASIDALY-QLVQKDALEMSKLGGDRMVEDLFSMLDDDPSV-GGVREVISSWLQQTAIHNPSAWIDLCQRIMTASQQMLDDEGQSLWRTQLFALHCLHDICTVVTTSGRME-HIDLLLAKRLQIRLPDLIKMAFTASA-AY-VIEIRLEGLLVLKDVIETFRSAPDPEYPEALLLEQHQAPIAAALTPAFSADSSPEIVAAAIDACAVFIGSGVVKDVSRMGRILKQLTSALEQTDEAGNLS--VGKLIDMSPTAS--GMLRISVLAAWAQLELASTKQLYLQDVIRPYRLAPQWVACLRDYALIRADSEFYTQLGKVVLLPFYNSAWPLILQAV--GKNMEEAEQHMLNAMAGQ-TDSTNEPVPFFIVLGIIYEALVTSPP----EDISIALRTLKCLASPRYSGKA--LLEPTVFKELISLCNRLAMVELTEVLTLVMSCSKICAHMIRVQVSSAFSTFETIAKTLSGSVRDVRGVACMLFAELLKDDLNTPLLPCLKALLSLIYGLLSSCLVDEMR-GREGAISVKSNLLAAVLIITIVPRSIKVARGVVELITQKLDE-GEEMALIAVHCAKTVAIAASESRSLLPGLI-EYIAEETWKTFLLGVILPTMTLCLTVKQLLSFATSSPDAFKEATNHLDVAREPLEQSLRRALG---Q-GQISLRS Copci MTSDSENGEIYLLQWLCTEKALLDIPIADLKQTQSEVESTLLKV-ISPSPGRVIRRVVGRCFVALYSRGETRMFDTLQALMK-L--VGDVKSAAWSCVGDIMAAFGSNLMSFMAEIALVSLKTAK-SSSLRYQALIAFQKALAKRAV--QESTLKDALKQMRY-ALTDKSLPVQRAACQVIVTIDIE-SILVK--NLENIDQTT-RQSH--AHLIGHLLSETNPKK-----DQEMLILLSNHLNRL-SRKIRVGIFE-FYVALLNKLGPNFVNFSLIVAHLLNEVVLLTRKLVLLRDLIGVRMLSEQGQITAIRELYLKRW-PAMMPGQAPSPVALVIVLREVAGLLQLGNADALAEPLVTLLSHPNTVRVNAAWALRFCYSTPLRLVVVDKLQKDLATLVTPVAS-ADVPARALGHAYGLAALVSIIPQRPLYVSYDVTA-KILDIATQILKRAG-EHDLKVAEVEIEVSWTLISALMSLGPNFV--RPHLSQLLVLWRNALPKP-TNKD-TANNRSVADFLLHVRECALGAILSFLQFNASTLVTLDVARRVASVLSNALSFANNSQNVEPADSQPPVEALLRRRVYQCFSALAESTQMTLLQSAVSLFAAAIASSSGSFTTVWNSTDGAYGVTSHDGESSSTNQRDSIEPIFGACEHDVVDSAIDLFSRLLSIKIINQLLESVRSPRLEKNAGRKSAVFINAAVAIVLALRVANGQVTSLLSPFLMEAIIILRSAGSESMGRLASLSGT-NYLTSQIKDLVDKVVSNRNPYGRAGCALAFGSIYTHVGGLAA-GALLKTTINVLMSLSNDPHPVVHFWALNALTRVINAASLAYAPYVTGTLGLLLKLYLKEGG-TLGNSNISDCPAYPVM-CQIIDAIINVLGPDIQESPRVRTLILNLVHEREEDDGIR-VESIKCIQHFLMFAPLVKRF-RKYLSSGRRPLKLASINALY-QLVQKDALAMSKLGGDRLVEDLFAMLDDDSSV-EGVRNVITSWLQQTVIYNPGAWIDLCQRIMNASQQTADDEGESLWRTQLFALQCLHTICTIVSNSGRKE-HVNAIYARSQGVRVADLIKMAFTASA-AY-VTEIRLEGLVVLRDVIEVFASSPDPAYDDALLLEQHQAPITAALTPAFSSDSTPEILASAVHACAVFVGCGVVKDVSRMGRILKLLTSALEQSKESGMLS--LGETGEMSPNAS--AMLRICTLSAWAQLQVSSTQQSYLQNVVQPYRLASLWIASLRDYASIRVDSEFHSSLGKEVLLPYYRETWATILQAV--ATSMQTSDPHIVAAMDGR-ELGKQEPSAFFILFGLVYEALSTSSS-SQRQSDYIALQALKCLVKPEYAGKA--ILEPTIFDEFTSLLYRIAMTELIEALIFASTCLRICSQILRTTASRAISAFSTIATGLETSVRDVRGVGILLYCDLLKDDLVGPTLPAFKSLLDLMHALLSTCLVDEMS-NRQGPGAIKNNLLAAVLLLTVIPQDVKLGRQVIELISQKLVD-GDETSLTAAHCAKTLIMAASAVKLLIPGLV-QYIAGEIWKAFVLGVLLPTIALLLTVKQLLAFATVSPAGFKDAAAKLDPVRELLEQSIRRAVAG--A-TQISLRS Croqu1 MERDEDRGEVWLLQWLHLQTDLDRVDEDTIKASQSQIESDLIRL-LSPPPGRPIRHMIARILVKMFTRAEQRLFDVIATLLR-V--AGTEPPSCFYVVGEIMKVHGSQVMSQFAESVLTSLRIIKSSSSLRFQALHCLNSSLGAKTLASSDNLAKEILKTLRS-TLADKTYSVIRGTVECLLTLDIE-SYLIK--GLDNVDFVT-RRSL--SNLIANLLAAASTKKKKDGQEEEMLALLSTPYSKT-SRRTRNGLID-AYGNLLTLLGSTWVYYPEILHHIITDIGLISRKMALLRDIISVRLLSEQGQVVAIREIILNKW-PALMPTQPPSKYALVIALNEVAGLLQVGSAEVLYNPLIRLLGHPSSVQISAAICLRYCLVAPIKLHTLELLNKDLSQLSTPGAP-SDANKRAIGHAHGLAGLMSVISLKPLYVSFDVSS-KVMSLAIQLLKQSG-SHSLQISTFEIQVAWILVSALASLGPNFV--RLHLSQLLILWKNALPKP-TAKD-ANNNRSEADFLLHIRECTLSAILSFLKHDGDKLVTLDVARRIVVMLNNALAFLAEKKYLQEHEQAPFADLLMRRRVFQCFIALVESIQVSLLETTLSFIAAAISASTGSFTSVWDSTDGSFGVTSLGLGGLVSD-RDLTDPCIESYEHDTIDSAVELFALYLKLAVLDKLYAYVNSPKIEKNPGRKMAILVNSITAFLICGRTCEPPVASLMKDILKEGLIRIRAASAEAFGRVCALAGN-TYMVNQIQHCVSQIVNNTDPHSRSGYALCFSQIYTQVGSLSA-GAVLKTVVDILMSLSADSHPLVHFWALKALSEVIHTAGLAYSPFLNSTLGVVVKLYCIESG-STGHVNVRNLPTYQNF-CKILNAVIGVLGPELLSRSQARVLLQLLNEEEESDDGIK-VEALKSIQHFVMFSILIQTL-RKHLSSNRRTLKVASINSIY-QLVQKNATLMSKIGGDKLVVNLFLILDEDPTI-EGVRDSIKSWLRQTADSNPTAWIDLCMRIVTAAQVKADEESQGLWRTQLFALQCLHEVFLTVIRNKKTE-HFSAQVAKSKGLRVSDLIKMAFTAST-AS-IMEIRLEGLNVLRDVIENFKYSSDLDFDEAPLLEQHQAPIAAALTPAFSHDSFPEVLASAIQVCAVFVGSGVVKEIDKMGRMLKLLTSALESCRDAEIIS--LGEMKELSSTAS--VMIKTAVYAAWAEFQVTSVKQSYLCNVIKPHLLCPLWVASLREYARLKSDED-QGSFTREICLPYYESAWLKMMKAT--AYLIKAKDPFILRALDGA-DTPRDEPAMFHVLLGLVYEAAALTASASSAAQVMETLISLEALLQSDVAGIQGLKKDTAVFGEICNLCYRLAATEVVRCTQLAL-CLRVIMQIIKIPSMSGFSACADLADRSLSTTRQIYGVAMGLFGEILKDDLVGPVLPALKTIVEVLHALISQALVEEAR-TQNANSAARNNLLACVLVFTSLPPTVKISKAALELISMIMASDEPEAAATAIHCAKSLILTRSQLTQLLPALV-NFLATEVLKTFTMSIFLPVYLILLAVQQVLALASLDAVAFKEATNALEAQRACLESALRGSIKT-SS-PSIELKS CryneH991 --MPDDGSDLALLHWLRAEQAIEAMDPEDLSKQIQSLHAFFLKLLLPPKPGRPIRHLV---------------------LVK-A--VSDGGSASWYCIGEVIKEHGKN---------------------LRTQAMVAFSRSLAGKAL--PDALVKDLLKSLRS-GLQDKALSVQRACAETFISLTLD-MVAFK--SLETADHLT-RRAF--SRMLAHFLAEPSKKTEA---EQEMLKYLSIPYNKS-PHKLRNAIID-AYATLFTTLGGEYVRYGEIVKHIMDQIILATRQVALLRDLVGERLLSEPGQVSAIRELYLKRWQPTLLPGQKINKNVLIVVLREIAGLLQLGNAELLAEPLVRLLAHESSVRLSTAFTLRFCATNSSQLVLIADIEKDLNLLSSPTVP-KEVAPRLVGKAFGLSALIAISPARPLYVSHDVPT-KVFDLAVSLLKRAG-DHEIPQASTEIQVAWYLVTGLMSLGPSFV--KLHLPQLLVLWRNALPKP-SSKD-TSVGRGEAEFLLLVRECALSAVLNFLNHNQ-SLVNIDVARRLTTLFTNTLNYVNGAEALRQANLPN--EATLRRRVLQCFTALTESTQPALLQAAITVFAVAITAQAGNFIGIWHSADGAFGMTSLNGEEDEGEERDKVEPILGSLEHDVIDAGLALFSILFQVQSLATLSSHMRSSKLEKNPGRKQAVMVNTVIALRKTLKKVSAQVSEMIRSLLQDAIFSIRSTSAEALGLLSSLASP-TYLSSQVQWLVDQVVTNRSPDARAGCALAFGAIYSSVGGLAG-GPILKTIVNILMSLATDPHPVVHFYAMKALARVVDAANLSYEPYVPTTLGMLSNIYLPEGG-SLGSVNLRDLPAYQAI-CRILHALIGVLGPELQEPGKVRSLMFLLVHEEETDEGLA-VEAIKCVQQFLMFAPLVQTF-RTHLASPRRPLKVASITALY-QIVQRDPVLISKLGGNQLVEDLFGLLDDDPSI-DGVKKVISSWLRGTAAALPSGWIDLCQRIMAAQKAATDDEGESLWRTQLFALECLHDIVISVAEGNRPE-HFDPVIARRIGARVGDLIKMAFSASA-AG-VMEVRAAGLVVLRDVIEKFSASPDPDFESALLLEQHQAPIAAALTPSFGSDSAPEVLSLAVQVCAVFVGSGVVKEVPRMGRILKLLTGALEQY--GESLS--LGDVEDLSPSAV--IMLQISILTAWAELQISSVRQSYLTDVLKPYRLAPFWIGALRDYAQLRTDPEMTAGLGREVLLPYYEHAVPKLLHAV--AISFAINDPFALGAMNGQ-RYDRPEPSAFYIVYGLSFESLLKTVG-----SLASALKAMQSLVKPALSGTT--VFEGQFFDELCTVCYRIAMSEAVEVMSFATSTLAIVAFTLRVPTKEAFMAYAQIVECVEVSQKDMYAVGLHLFMGLLESDLVGGCLGCLKVQVEIVHGVVSACLIDDMR-TRVNPVAIKNNLLAVTLILTALPADLKVSRNLVETIGQYLIE-RPELGLTAIHCASTILPASLRTLHLLPPMI-TYISQAVIKSLGYGVLLPTLCLMLAAAVLLGLAQSGPAAFKEATMAMKDERGELEHAIRDAVQG--A-AGIELKS Crypa2 MSSGSEQQDLFLLTFVSLSKHVLSLSADDCTAQQFYLKREIFQI-INPAPSRVVRNSLGRCVAHIFGNGDRKLLETINDLVAIIT-AGKSKAAAVVCLGDVFGAAGDSAISYHQLACTVLVKLLKSSSNLRAACFTALGKIVVGQML--DDSIARDIWKQGRSHASSDKGALVVVAACRCLRSLDFD-KIQFK--AFEYGSSQA-RRAA--AECLAEALVKTPKT-RQSMPPADILRVLSYQYGKT-SNKARSAIGI-CYSTLLQRLGEKTVNYMKIVENLTLELLLISRRIVLLQDVIGKKILGETGQSHAAKVLVLKNY-PQALKEREPTKNMLIAAMGALGSLMSLGSAEAAREGLLQVLQHPSTVQVYTSACLKFVLNCPQQLVCMNSLSRELSVLGT------NSTRKCVGFAHGLAATLSASPSRPLYGSVDINS-RVLTMATNLLKSSG-KLELRVASTQIQVAWTLIGGLMSLGPNFV--KIHLSQLLLLWKNALPKP-LAKD---NTRNYLEFLAHVRDCALGSILAFLEFNS--LLTVDVSKRIATMLQSTTAFLKTKKKTSAERLAPALEMMVQRRVMQCYIKLEALLQSNLLTLAISLFAAAIANSAGTFDTIWDVDDNGFGVTGIPGQHESSIEDNSPEPVCAALEHDVVNMAIQLFAFAFQESILEQIATFMAAGTLERDNARKAAITVNVAAAFLSTLKVANMQVEKLFQDMIRGFVLYVRSLGYAAIARMCNACGN-AFTNSEIKFLVDTIVVNREPSARAGCAMALGCIQAKVGGMAA-GYHLKTILGILMSLCNDPHPTVHFWALEALACAADAAGLGFSQYVSGTLGMLAQLYTSEIA-SAVSMNLEELSTTASV-ARCVDSLINVLGPDLQDIAKSRELIFTLVGYSEDDMHVQ-KASLDCLEHLSLYAPYVKLL-QKYLRSDHPTLRDVAIDGLY-NIMKRNSYDVIEAADPGFEEDLWLALDRNPEH-DGIRNIIQNWMRQTCLTDTADWLQRFQAVLTGPKKTTDEEVAGFWQVIAFAMSLLYEIFTLINKD---------VMSNG---RIADVVRMAFSAST-SG-VLEQRIWGLKIIGAVLKMFGKTPDPDFDEAMLLEQYQAQISSALTPAFAADSSPELASEAVNVCAAFIATGIVTDVDRMGRILKTLVTALENFSQNDNAG--IGDLKGLSSNAQ--VMVKMAVFSAWAELQVASTEQAYLLDVLKPYILTPLWLESLRDFAQLRFEPDIYAALNRETLLKFYQDSWLKLVDAI--ASLIGQDSEFVFDALDGK-ENSRDEPLAFFVLFGIAFEALAAKPGASNEQTL---LQALKKILHPSVSGHA--IYRDAVFAESMDLLDRLVLTEIVDIAALCVELTRIIVLVLALPNLTSLNSLVDAAEVFPSVIKDLHACIIHIFATILATVIVPQALPTLKRFIAQLQGCLRRFLYLHGQ-KREKPTDVKNSLLAITILFTG-------GQNHLTIVTKFLVECLSDTAKIATNCVRSLLLQSK-ARFLLPRLI-TFVTSLVAHTLAMSLVMPTLLSRATSARLLELASADQASFRGVVAGLSEQKEFMEEVIKSGR------STIALKM Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------LECLVLCFSGLSPYHRISQEQTRMSQLAGLRALVAGP-GSVRSALKIARASVESTP-----------------------------AGLRLIEAL-VSCQFVDPAGLQQLVAIIFKSLEDASACRLAMSHTLAFVLAGGGM-A-----------------------------------DPE-T--------GDDVKPH-GGAGYAGSLGASSMSTSSFGMRRSGPADRVLELLGSPHSRT--QQLLAPIADHHRAAICAQSGGALSASASLNAPLGAQALLVARSAVLLSR-IAKRLDSEA---GLAGMLEMEALV--DSPPEASHAGRLAASLG--------SAAETIDQRMRSLLHSPLSVDAVRAAAAGAYFAA--CFGAGALLAAAVFSAV-ASSP--PELLAAAGVSPAGAATATGAGGNGAARARPLHE-LMPAA----FAPGG----AVVRSVW------VRGAGAAAAAMLA---SETPQ------VLLPTSGPALG-SVATPAPGPSLATMSDADLVAST----LAGFSSAAPAALQAAAGIGLPA------TGPGASSTSTPAA------EPAGGALSA-S-LAASGLSLAASGLAAAVSAVSPALMARWR--DPQQGTSAR--------------GALGALERFLLASAAGVPGVPFGPELLATAVEVLSEAALGRQTHRTHAAATDHVAGIVAATRGGNDFFSVLLRPLASTPAVLLRTVAAEAFGRLTAVTAA-SQVTAAIRTLVKHAIPASDGFIRAGYTLAIGYTLRHVGVMSA-SSHLHDTVGILNSLACDGDHLVHAHALHALATVLDVASVAFRPF-----TQAVLSLLPGAG----GLSGESYGIPVSL-GRLVNGLVLLLGPELAMVRPNRELIFSMVDEVSSDLAAA-REALRTREQLLLFAPLVPVL-QQCL-----ALRQAALGCLR-QLIGRSAGVVLRS----LDEQL-CRLHRRPAVLALISSVLMDLVLGASHSHAARWVGLGMAAFAAAAAAALEDA---WQTKALLIDILNSLIIQLSSNPV---HFDA--------RLADLVRVAFNAAT-SQAVPALQSSGLSLLGTIIRYFGPVPDPELEGHSFLEQYQAQISASLRPAFAEGTAPAVRAHATAVCAEYLASPVLTDAHDAAR-MAGLVRSLWHEDDSNVTGANIERALRVSSLA--------ALATMYSALRVRQLAAPALAAVFRSAGLAREWMAALR----------A-AAAPSETLLPFYLNVRHSLVRAL-----LALPDAALLDALGGG-HPADAGDSS----FGGVISSLVAGQCAHRADPFSVALRLVARCLGLGLKTAVP-LVPPALLFPLSHALRRAMQEGLVQALSLFPAAVGATSGGMAAPPAGAPLALHALAGFLRVALRPIAQLFAAVCSAMLAASEDGDLSGAGGAAAGLALALL--ELASAKPAADPGPSSQPQHLPGSIALLVVHAL---LTSPYSALIVSALVGRLAEAQLTALRCSRTLLSLAVALTAVVPRVV-ASLAPAATTGRLLQEALRLLVSVLAADSLLQAGLLAPAAFRSSIE---PAQRQ---------SASAS-ARMDFSD Fomme1 MSSGNDDGEIYLLKWLATEKDLKSGTPHTFKTSQAIYETKLLKV-VAPSPGRPFRNIVARCLVLLYSKGESRLFDTMQSLLK-T--VGDMKMAAFYCIGELMSALGSQIMSLMAETAAVSLRNFRASSNLRFHALTALRKALAGRAV--PESTMKDVIKQSRQ-ALNDKALPIQRAAAEILIVLDVE-SIVVK--SLENADQAT-RRAL--SRLVGHMLADTSKKKDQKNGDAEMFSQLSTHFNKA-SRKTRIGIFD-FYAALIATLGTSFVNYATIVKHFFTEVLLLINKLVILRDLIGVRLLSEQGQISAIQELYLKKW-PALMPGQAPDASVLVIALKEVAGLVQLGNADALADPLVTLLSHPSSTRVSAAWALRFCFATPLRISVLELLQRDMSTLSTPAAP-SDISARAIGHAYGLGALFAVIPERPLYVSADLSA-KVFDTATQLLRRAG-EHDMHVATVEVEAAWTTIAALMALGPSFV--RAHLPQLLVLWRNALPKP-TTKD---NSRDSAEFLLHVRACALGAVRAFLRHNARALGTRDVARRLAGLLGNALSLANAAQGLGAVAGAP--EALLRRRVYQCFTELPDATQTALLQSTTSLFSAAIASA-GNFTSLWNTTDGAYGVTTLGASDLPGQRRDSIEPVIGSCEHDVVDAAIELFAALLCGRVINEALESTRSQKLEKNAGRKAAVVVNTTVAIALALRIAGTQIANNLSSFLMEALIILRLASSEALGRLASLSST-TFLTSQVKTLVDQVVNNRDPYARAGCALAFGAIYTHVGGLAA-GPLLKTTINVLMSLGNDPHPVVHFWSLCALAQVINAASLAYAPYVPSTLGMLFKLYLSDGG-TPGNANLKGHPVYQVI-CQLVDAVVAVLGPDIQESNRMRGLVMNITHESEPDGGVC-VEAIKCIQHLLMFAALVNEL-RAHLSSSRRPLKFAAINALY-QLVQKDALAMSKLGGDKLVEELFGMLDKDASI-DGVRSVITSWLEQTVVYNPSAWIDLCQRIMTASQQASDDEGQSLWRTQLFALRCLHSICTIVARSGRRE-HLDIRFARSQKLRVPDLIKMAFTASA-AY-VTEIRLEGLVLLRDVIEVFAKSPDPDYEGSLLLEQYQAPITAALTPAFSADSTPEILASAVQVCAAFVGSGIVRDVSRMGRILKLLTSALEQSKESGMLS--LGEAGELSPNAS--VMLRISTLSAWAELEVASIQQSYLKDVVGPYRLGVLWVAALRDYASVKGDSEVYASLGREVLLPYYEKSWSIILHAV--ATAMKVGDPYILAAMDGL-ESTREEPTAFFAIFGLIYEALATSSAPTVRQNA-IILEALKSLVKPEYSGKA--LLESTIFDEFTSLCYRMAMTELVEAVVFATSCFRICAYVLRISGPGAFAAFSAVAEAFGPGLRDMRVVGIAIYAELLKEDMAGPTLQSLKAMLDLVHGLFSACLIDEMR-GRQGAISVTNNLLAAVLILTVVPPYVGFSEAALELISQKLLE--KEVSLTAAHCTKTIVLAGTSMKLLLPGMI-EYIADEILKAFTLGVLLPTLALLLAVTQILSLATLAPGAFKDAMSKMDEMKERLEVSVRQAIKGGAG-AQISLRS Fusgr1 MSSTQEQQDLFLLTFVSLAKHVLSLEADDCTAQQFYLKKEIFQI-INPHPSRVIRNNLGKCLAHIFEIGDRKLFETINDLIALVS-SGKSKTAAVVCLGDVFASAGDSAIGLHQLACSTLLKLLKASSNLRAACLTALGKIVIESSM--DEVIARDIWKQGRNHASSDKGHLVVASACRTLKVLDFD-KLESK--AFDSPSVQV-RQAA--AECFAEALFKKTKKKRQSTIPSDILKNLASQYTKA-SNRTRAAIGV-CYGKLFRRLGEKVVNYLKIVESLAIDVLLVSRKIVVVQDVIGRKILGESGQISAAKSLIFKNY-PQALAEREPSKHTLIATLSAVSSLISLGSAESCRDGLLQVLQHPSTVQVFASHCMKLVLACPQQLVCMNSLSRELSQLGS------NSPRRCIGFAHGLAATLSASPARPLHGSVEINS-RVLTIATNMLKSSS-QAQLRVASTQIQVAWILIGGLMSLGPNFV--KIHLSQLLLLWKNALPKP-LAKD---NTRSFLEFLTHVRECAMGSILAFLEFNS--LLTVDVSKRIATMLQNTTAFLRTSKKNSNQRLAPSLEMMVQRRVLQCYVKLESLLQSNLLTLAISLFAASIANAAATFESIWDVGDNGFGITGLPGQQENSDDFDSPDPICGSLEHDVINAAIQLFAFAFQESILEQIRTFASAGTLIRDPGRKAAMNVNLAVAILSTMRVANQAVEALLQDIVRDFVLHVRSLGYAATARLCNVYGN-AFTNNEIKYLVDTIVGNREPSARAGCAMALGSIQTQVGGMAA-GYHLKTILGILMSLCNDPHPVVHFWALEALSLASDASGLGFAGYVPSTLGMLVQLYVAEIS-SAITMNIEDLSTTSAI-ARCVDSLINVLGPDLQDALKSRELIFTLVNREEDDLLVQ-RAALGCLEHLSLYAPYVKIL-QGYLMSESTTLRDVSVDGIH-NMMKRNPQDVLREAETGFEEQLWLVLDTAPSH-DGIRNIIRNWMHSTCLAETNAWLQRFQAVLQSGSRGGDEEVAGFWQVTTFALSCIDEMFAIIAKD---------VTANG---RIADVVRMAFSAST-SS-VLELRIWGLKIIGDVLKMFGKTPDPDFEEAMLLEQYQAQISSALTPAFAADSSPELASEAVNVCASFISIGIVTDVDRMGRILKTLVGALENFSDSENAA--IGDLKSLSSNAQ--VMVKISVFSAWAELQVASSEQHYLLDVLRPHILTPLWLESLREFARLRFEPDIYAALNRETLLRFYQDAWLKLVDAI--ASLIEQDSEFVFDALDGK-ESDRDEPVAFFVLFGLAFEALATRSGAAHDQTL---LQALKKILHPSVSGHA--IYRPDVFSETMDLLDRLVLTEIVEIASLCIALTRIIVLVLTLPNLSSLNALVDAAEVFPAIIKDLHACIVHIFATILSTLIAPQSLPTLKRFVGQLQGCLRRFLYLNAQ-KRESPQSVKNCLMATTILFTG-------GQNHLPLVARYLMDCLTDTAKIAANCVRSILLQPS-ARYLFPRLV-AFVTALVAHTLAITVVVPTLMARATSARLLELAATDQEVFRAVVGGMSDQKGFLEEVIRFGR------TTIALKM Galma1 MSNETENGEVYLFQWLSTEKKLESIPIADLKPKQGDLEKVFVKI-ISPTPGRAIRNLVGRCLITLYTRGETRLFDTLQAFLR-I--VGDFKAAAFSCIGDLMSTFGSNVMSFMAEITTVTLKTHK-SSTIRYHALITLYKSLARRAV--TDATCKDILKQMKS-GLTDKSLAIQRAASQVIIAMELD-SIIVK--SLDTVDQAT-RHSH--AQLVGHILAQVTQKQKDGTADNEMFVHLSTHFNKA-SRKTRIGIFD-FYAAVLTKLGASFVNFSLIVSHLVQDIVLLTRSLVLLRDLVGVRMLSEQGQIAAIQELYLKRW-PAMMPGQAPSSPVLVVVLREVAGLLQLGNANALAEPLVTLLSHPSTVRVTASWALRFCYSTPLRLTVMDKLQRDLSSILNPSSS-IDVPLRTLGHAYGLAALVSIIPQRPLYVSYDVSA-KVLDMATQLLKRAG-EHDVKIAGVEVEVAWTLIASLMSLGPNFV--RPHLPQLLVLWRNALPKP-TTKD-SVTNRSIYEFLLHVRESALGAILCFLENNSSTLVTLDVARRIASLLSNALSFANNSQNVEPADSQLPVEALLRRRVHQCFTALPDATQMILLQSVVSLFAAAIASSSGTFSSVWQSVDGAYGVTFNSGSVSQGVHRDTVEPILGACEHDVVDTAIELFSKLLTQKVISQLLESVRSPKLEKNAGRKAAVLVNANVALVLALRIANTQITSLLSPFLMDALVVLRSAGSESIGRLASLSGT-NYLTSQIKDLVDQVVNNRNPYGRAGCALAFGAIYSHVGGLAA-GPLLKTTVNVLMSLINDPHPVVHFWALNALARVINAASLAYAPFVSGTLGMLLKVYLREGG-SLSNSNISDLPAYPIV-CQIIDSVITVLGPDIQESSRTRALVQSLVNELEDDEGIC-VEAIKCIQHFLMFAPLVKRF-RSHLSSSRRPLKLASINALY-QLVQKDALSMSKLGGDQLVEDLFGMLDDDSSV-QGVRNVISSWLQQTVIYNPSAWIDLCQRIMTASQQVADDEGESLWRTQLFALQCLHEICIIVSTSGRRE-HLNAILARSQGIRVSDLIKMAFTAST-AY-VTEIRLAGLVVLRDVIEMFAASPDPAYDDALLLEQHQAPITAALTPAFSSDSTPEILASAVHACAVFVGCGVVKDVGRMGRILKLLITALEQSKDSGMLS--LGEAGELSPNAS--AMLRISTLSAWAQLQVSSVQQGYLENVVKPYRLCSLWVASLRDYASIRIDSEFYSSLGKEVFLQYYSKAWSIILQAV--ATAMQAGDPHILAAMDGQ-EVNRKEPTAFFVIFGLVYEALATSSATAARQSSVVSLQALKCLVRPEYSGSA--IMEPTIFEEFISLCYRMGMTELVEMLIFAASCLRICAHILKTSPSRCLSAFASIAASVNTSQRDIRGVAILLYNDLLKDDLVGPTLPALKTLLDLVHALLSACLIDSMR-GRHGAISIKNNMLAAVLVLTVVPLWVKIGREVVELISQKLLD-EDEVSLTAAHCTKTLILASASARLLVPGLI-EFVAGEVWKAFLLGVFLPTISLLLTVSQLLSFATTSPVSFKDALGKLDATRELLELCIRRAVAA--G-AQISLRS Ganpr1 AATSSDKWEHNLFLWLGLEKALTGASKDAIKPHQAEVEKTLLSI-LAPRPTRSVRSLVARCFKALFTYGEGRVFDMVVALQKELTKVVNDK-AYISTLGNLHHDFPSPIFSLLPESLSLMLRILRSHPPQRFESSVAITKLVSGRKV--DLSQAKDILKTCRE-GLKIAVMGIRGVSAECWHAVDLDHDLLYKH-TFESATYPV-RRST--ASLVASILT-------TVTASQGMLGILGSNFANK-TLQARLGLVQ-AYASLFRSKGIKWVNYTVLAQHVLETT-TAMWSSSLLREVMG-KMMTEAGKEKAVGSLPTSKW-------------AIIAALNEIAALVDLGTGD-VVDQLIGLLNHPSSVTISAAWTLRVCLAEPMYLAITNQLQRDSTLLASPSAN-VELFHRLSSHSLAVACLNSIIPHRPLYSSFDLAS-RVFALSTSLLRSASSGKDYRTMGVQASVAWTLVGSIMGLGPQFV--KVHLSQLLLVWKNQFPKP-GPKD---AQRSYDEFLLESRGAALAALLAFLAWCGAKLVTLDVAKRIVVCLNNTVSFLGT-----EGDDIPGSEHVVRKRLFDCYRHTYESMQPTLLGLSIEVFTAGIMNGLGMSVHVAYEVDGEKGVS-----------ADTDVPTIHAPEHDVVDSAVEIFAMIFQEQIIERLVKSVTKKGGREQPGLGYSVHMNVITALLGVLKYVSPKVGEYMQNVVQIALTSMRAIASETLGRLAHAMSTATFINPFIQSLIDEIVNNTQPEARAGAVLALGCTFSHVGGMAG-ASHLKTVVQILHTLSADPHPLVHTWALNALWLTVDGAGLMYGPYVKQTLSLVAKLYMPVTK-HAMGN-YENTDVYPSL-ARILNAIVGVLGPELEATPSLRSLVLGLYESADEDPFVM-VEAIRCIQQLILFAPLIPFL-QFQLAQDQYSLRKACVTCLY-QLVQRDPGSVLENATSGLEEQLFGLLDDDQIR-DEIKDILIGLLKFVAVVNPSRWLDLCKKVLMSGSPVADDDENFLWKTHLFALFCLRKLIAEVFASGRQE-HIDLALAREAKKRLNDLIRMAFAAAT-AP-VNDLRLGGLDLLEDLLGRFGSAPDPDFEEHALLEQYQAQISAALNPAFSPDSPPEIMATACRVCASYIGSGINKDLSTLSRVLKLLTNSLERCKETSNPS--TESV---SPHAT--IMVKLAIQKAWAELHAAGFTHPYLKEVVMPIILAGLWISTLCEYARLKLEGDLYMEATQDVILPFYRESWVVLLRCV--SSLVSMKNSIILKELSGT-LSP------FNILVGLCVEELTTKMSGTVSSN---QVSAMKSFFDPEVSGGRAVFLDKVFYLELLSVFERLLDSSLVQTVQIISTTMRFFIKVFDVPLLSAFARLVAIQSDIAVKLESFLFVWFAVI-----RPVAPRALACLKEVFEIVQRLCKNLL-SKEP-NPSTPDS-RNTLLGVVVLVTLCPRSTLQKQITAS-LVDAILESTTLSNLVALQSVKSLLALSVKVRFLVPPVA-LFVHEEALRVLVLALLIPTFISILSAATLMQLAGQNPAAVRVVIAALPEARTKLERAFRYEVKEREA--KIQLK- Gloin1 ---------------------------------------------------------------------------------------------------------------------------------VRLEAIYTINRSLASKGV--TESIVKDIMKQMRS-GLNDKALIIKVASVQVYYT-ELD-NLLVK--LLDGSNQTI-RRSV--SSYIATLLASSTTSKKSSTLPEEMLTNLSTIYNKT-SREVRAAIIE-TYSALFLQLGTKYVNYSFIAQHLLKDLVLNVREHCLLRDVIGTRLLSEQGQVTAVRELWLKQW-SA---NQEPSKLSLVCAANEISGLLDLGGADVVADPLVTLLSHSSSVQIATAWCLRLCYSLPIKLKVHGLLSKDLNNLSNQVTS-SELPKRTLGYAYGLAALLSVIPSRPLDVSFEVSA-RIFSLSTQLIKTSA-NKDLSVASIQIQVAWILIGSLMSLGPNFV--KLHLPQLLILWKMALPKPNSNKE-S-VSRSETEFMFHVRECVLGAMLSFLLHNSK-LVTSDVSKRLVALLNNALTFTLLPNNPTSISIAPQLENMLKRRIFQCFVVIYDNLSTQLLKLSVSQFAAAIAAAVGSFTSVWTTGDEAYGVTSRDDEEGNGRKRDLVEPIIGAPEYDLVDYSLELFGLVFQEVILDQLIKSTKHPRLEKSPGRKMAVQVNMVIGLLAIFKNIDKRIGGIAMDMLQEAIIYLRNAASEALGRLLSIVGG-NLVTTQMQLLVDQVVNNREPDTRAGSALALGCIYSHVGGMAA-GSHLKTLVGILLSLSSDPHPVVHFWALYALAKVIESAGLMFSQYVSSTLGIIAKLYMPGGG-SVGTTNVGGFSAYQQF-GKIIYGLIGTLGPELQSSAKVRNLCLNLMIENDEEQMVV-VESIRCLQHFIMFAQLVAFL-QFQLSSKHLPLKEVAVTCLY-QLVQKNAKHVFEVAVPGLDNQLFSLLDTDPTI-DGVKDIVKSWLNQTAIDNPSLWVELCRKVMASAGAPI--KTNTFWRTQLFALQCLRQVVEVISSSGDKD-HFDLVIAKKK--RVQELIKMAFIAST-AV-VSEMRLEGLTVLRDVIE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------II-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 MSAPEEQQDLYLLRFTALVQYAATLDKVGLSSKQRSIIQELFKI-LKPSPTRVIRNNIGRCFNAIFSKGDRSLYDSVTQLLGILN-AG--KSAAAVAIGDIYAGAGDSLFTQSSVVCCALLRLFKSAQNLRISLYTALKKVIISSPA--DEQTAKDIWKHARNTATNDKAIATQASACYCLEQLDFE-NLKWK--VIDSPSPSA-RHAA--ASCLAAFLIRRPKKKKQTTSPPELLKQLSLQYCRT-GNRARAGICM-CYKQILRGLGNAFVHYAEIAGHFLITLLLMTRQFILLEDTVGCEILRENSRINAAKWLVLKDY-PKVVQEREPSKHTLTCTLSALSAIISLGSADSCRDALLQILQHPSTVQIHTARCLRFVLACPQQLVCMNSLNREIGQLST------HSNRRCLGYAHGLASMLSTSRLQPLYGSVDVYA-RVLSRATDLLKTSS-SLELRIASTQIQVAWILIGGLMPLGPSFT--KIHLNQLLLLWKNALPKP-LPKD---NLRGPLEFLAHVRECALGSIYVFLEFNS--LVTADGSRRIAAMLQNTVMFLDNKLKSASQRLSPSLATMIRRRVLQCFSKIEVLSLSNILGLAISSFATSIASSTTHFDNIWDLDDNGFGVTGLSGRRKGDNSVELSDPTCQAMEHDVVNAAIDLFAKALQESSVEQIATLLSAQSLNRNPGRRSAMTVNIAVALLLTLKIAYPATEKVMQELIQTFAIIVRYIGSEALGLLCNSSGN-AFTNSQINSLVDLIVENRDPSTRAGCATALGCIHSQVGGMAA-GFHLKTIVGVLMSLCSDPHPIVHFWALEGVGRVAESAGLTFSAYVSSTLGMLARLYIEEAS-SVTTSNLEAFPTPVSI-SRCVDSLINVLGPDLRDISKTRELIFTLVKELEKSTALV-VESSKCLDHLSLYAPYVRWL-QQELASKKASMQDASIRGFN-NLMKRDADLVVRTALPSLEDEFWLAFDTATDN-EALKNIIHNWMQQTGLTDTDVWIQRFQKVLPATVNTADDEVAGFWQTRNFVMSCLSELLSMVSKE---------LLPDQ---RVGDIIRMAFSAST-AN-VIELRVWGLKIIDQILKMFGKTPDPDFAEASLLEQYQAQISSALTPAFAADSSSELASEAINVCATFVGTGIVTNVDRMGRIFKLLVVGLDNFARNDTTE--IGDLNGLNYNAR--VMVKLALFSAWAKLQIASNDQNWLAQIVQPYTLTPLWLASLQEFARLRFEPEIYAALNRETLLKFYQDSWLNFVDAI--ASLVEKDSDFVFDALDGKLEPSRDEPVAFFVLFGLAFEALV----EQSNQSL---LRALRKILHPSVAGNA--VYQPAVFSETMDTLDRLVMTEIVQMADLALHLTRNITLVLTLPNLGSLSSLVDVTSVFPSIIRDLRACILHIFTTILATEVVPQALPIFRRFIQQIRGCISRLLLTIAQ-RRESETSAKNTLLSLTIILTT-------SSHVIPLIPRILLDCLQDLATVAAGCLRSILLSPCPARFLFPRLV-AFIMGTVTLTLAMALLIPALLMRAIAAALLELAKIDAQTFRGMVTRMNAQRAFTEEILRKG-GGKQG-KSIALRM Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MSGEEDN-EVYLFQWLSSEKKLSDVSLADLKVQQPGFEKSLIKI-VSPAPGRALRNLVGRCLVKLYTRGETRMFDTLQAFMK-L--VGDIKTAAFSCIGDLMAAFGSQVMSFMAEITIVTLKTYK-SSNLRYHALMALQKSLAKRAV--TDASAKDILKQMKS-ALTDKSLPVQRAASEVLMAMEVD-AIIVK--SLDNADQIT-RHAH--AQLVGHVLSEAPQKK-----DVEMLLHLSNQLNKL-TRKTRVGIFD-FYAAVFVRLGASFVNFSLIVAHLISEVILLTRKLVLIRDLIGVRMLSEQGQISAIQELYLKRW-PAMMPGQAPSSLVLVVVLKEVAGLLQLGNADALSEPLVTLLSHPSSVHVNAAWALRFCYSTPLRLIVMDKLQRDLTSMLTPTAP-LDVPLRALGHGYGLAALVSVIPQRPLYVSYDVSA-KVLDMATQLLKRAA-EHDLKIGGVEVEIAWTLIASLMSLGPNFV--RPHLPQLLVLWRNALPKP-TNKD-STNSRSVNEFLLHVRESALGAILCFLQHNSSTLVTLDVARRIASVLSNALLFANGAQNVEPSDTQPPVESLLRRRVYQCFTALAESTQATLLQSVVSLFAAAIASSTGSFSSVWQSNDGAYGVTFNSEDSSQGTSRDTVEPILGACEHDVVDTAIELFARLLTVKVITQLVESVRSPKLEKNTGRKAAVFVNATVALVMALRTASSYVTTLLSSFLMDALIVLRSAGSESIGRLASLSGT-TFLTSQIKDLVDQVVNNRNPFGRAGCALAFGAIYSHVGGLAA-GPLLKTTVNVLMSLSNDPHPTVHFWALNALARVINAASLAYAPHVSSTLGMLLKVYLREGG-TLGNANVSDCPAYPVA-CEIIDAVITVLGPDIQESPRTRSLVLNLVHELEDDEGIS-VEAIKCIQHFLMFAPLVKQF-RSHLSSSRRPLKIASINALY-QLVQKDALAMSRLGGDRLVEDLFGMLDDDPSV-QGVRNVITSWLQQTAIHNPSAWIDLCQRIMTASQQVVDDEGES-WRTQLFSLQCLHEICTIVANSGRRE-HLDAIVARSKGIRVADLIKMAFTAST-AY-VTEIRLEGLVVLRDVIQIFASSPDPAYDDALLLEQHQAPITAALTPAFSSDSTPEILSSAVHACAVFVGCGVVKDVSRMGRILKLLTTALEQSKDAGMLS--LGETGELSPNAS--AMLRISTLSAWAQLQVSSMHQTYLQKVVQPYRLASLWVAALRDYASIRIDSEFYSSLGKEVLLPYYTKTWPTILQAV--ATAMQAGDPHVLAAMDGR-ELTRQEPAMFFVIFGLVYEALATSSPTSARQTNVISLQALKCLVRPEYSGKA--IMEPAIFEEFISLCYRMAMTELVEVIIFAASCLRICSHILKTSTARALSAFTAIGASINTSQRDVRGVAILLYCDLLKDDLVGPSLPALKSLLDLAHALLSACLIDEMR-GRSGAISIKNNLLAAVLVLTVIPSTVKLGRSAVELISQKLLD-VDDTSLTAAHCAKTLVASASTVRLLIPALV-EFIAGEIWKAFVLGVLVPTISLLLATAQLLTYATASPAGFKEAAGKLDPTRELLETSIRRAVQG--A-QQISLRS Lenti61 ----------------------------------------MVKI-VTPLPGRPIRRLVASCLKAFCMRGETKLFDTIQAFLK-L--LAETKPAATYCIGELMGTFGSQVMSQMAEVSTVTIKLYR-SSSLRAYALHALAKSLAKRAV--TDSVAKDIIKYSKH-ALSDKALPVQRAACEVLILMDVE-NVLVK--SLEGADQLT-RRSL--AKLAAHMLADTAKKKTRKEGESEMLLQLSTHFNKA-SRRTRVGIFD-FYSALLSHLGTGFLNYALIVNHFMSEVVLFVRSLIILRDLVGVRMLGEQAQISAIQELYLKRW-PALMPGQAPNPLCLVIALREVSGLVQLGNADALLDPLLNLLSHPSSVRINTAWTLRFCYSTPLRLGVVEKLQRDLTSLTTPAAP-SDIHLRALGHAYGLAALLAVIPDRPLYVSYDISA-KVFDMAVQILKRAG-EHDIKISQIEIEIAWTCIASLMTLGPNFV--RPHLPQLLVLWRNALPKP-TTKD-GA--RSVAEFLLHVRESTVGVIYCFLKYNSPSLVSADVTRRISSLLSNGLAFANTTSRVA-LNQEELMEALLRGRIFQCFSLLTESVQSSLLQSVVTLFAAAIASSSGSFTSIWQSVDGAYGLTSL---------RDTIEPIITALEHDAVDAAIQLFAQLLTTKVVTQLLNSVGSTKLDKNTGRKAAALVNITFAVVLTLRQGNSQVTTPLSGFLKDVLVVLRKASSEAIGRLASVAGT-NFLTSQVKTLVDQVVSNRDPHGRAGCALAFGSIHAHVGGLAA-GPLLKTTVHVLMSLINDPHPVVHFWALSALARVVDAASLAYAPFVSSTLGLLFKVYMPDGG-TLNHVNISDLPAYQVV-CQNIDAVITVLGPDIQESTRTRTLVLDLVHQDEEDDGIC-VEAIKCIQHFLMFAPLVLRF-RGYLSSSRRPLKLASINALY-QLVQRDALSMSKLGGDQLVEELFAMLDDDSSV-DGVRNVIASWLQQTVIYNPSAWIDLCQRIMTASQQAADDEGQSLWRTQLFALQCLHSICTVVGRSGRRE-HLDMAFARSQGIRVPDLIKIAFTAAA-AH-VTEIRLEGLTVLTDVIEIFAKVPDPDYEENLLLEQHQAPITAALTPAFSSDSTPEILASAIGTCAIFVGCGVVKDVGRMGRILKLLTSALEQSKGSGMLT--LGDAAELSPNAS--VMLRIATLSAWAELEVASTQQAYLVEVVKPYRLAPLWVSCLRDYASIRIDAEAYSSLGREVLLPYYVKAWPVILNAV--AIAMQNDDPSILAAMDGQ-ETPREEPTTFFVVFGLVYEALATSTS-AERTS--IVLQALKCLVRRKYCGRV--FNDPPLFEELLNLFYRMALTELVEAISLADSCLRICAYILRISGPRAFEAFSTVAASFGPSQRDFRAIAITLYCELLKDDLVGPTLQALKGLLDVVHGLLSACLIDEMS-GREGPMCIKCNLLAAVLILTVLPPTVQVGKSVIELISHKLVE-GSEVSLTAAHCAKTLIMASTSTRLLLPGLV-ECLAGEINKALALGVIMPVLILFLSVTQLLSLAAASPAAFKDATGRLEPMRETLEASVRQAL----A-SQISLRS Malgl1 LPASSDRTDLFLLSWLVIDSLLLE---GEVRGSGALVERCLC---ICLQPGRSVRCLVARCLVCLYRHSEAELFEVMGALRDVY--AADIPTAAMHVARELIMSHPHGVGSQFS-AVPICLRIIRTSSHVRYYALRLLESILAHDKL--PASMLKDALKTLKQ-ALHDKAGPVVRASAVCLELVDIE-TQLVK--VLASADRQT-RTAL--ARLAATLLIAPADE-------EQQMNLLHVHLSRG-SWKARVGVLQ-MYDALLALHGSAWLHLQEVFMHLVRDIARAVHRVL-----VHLRSLPEPAQERAAAYMILGMW-PPATPAHAPSEAMLTLTLDATALLVQLGELEALYESHMRLLAHPIAVQIRAAWWLSACDVQPLLLELLTFMRRDMAALSTPQHD-QSLRARLVGHSFALAALARISAKHPLYMRNDDVE-DVFTLATDLLTRSGEQNALPNASAAVGSAWMLVGSLMALGTEFV--RAHLPTLMNAWRQALAER-SYAE-----LDDAAYLLTVRHGALSSMHVFFLHGGHELLTQETARRLVVMQSHALAFLDA-----FASHAPAAAPLLRVRILRCCTHLLETLAPHLMSMSVELLATAISTSTGASQSPWTVHDGAYGMTSL---------ADSDTPVLGALEHDEIDAAAELFAALFQIGTSEFLLAAQRRPALDKQPGRRIAVLVNSVVALLGAVRTANERVNAAIKGVAQRALQMLRRAAAELYGYLASLAGS-GSLSMQMQFLIDQIVDTRHADGRAACALALGQIYTCVGGLRA-SPLTKTINSLTLSLATDPHPAVHACALDALAQVIEAAGVAYEPYVRSTLGLMTRLLSPEGG-SPGSSNLRDWPAYPGI-ARVVSALVGVLGPDLQEAVSTRGVVYALLLHQDGGDAAA-KEALLGLQRLGLVVPSANLL-RHAL---SRPILAPSAASLYCQMAQRGSQWLARYGGPSLLASLLQQLDRHPTL-SGVRTLVLSWLKDTAPARPCTWMDLCCTALALSFKHVDETATALWRTQLFVLQCMDEVFASVQRA--PE-HVGSSDARDRRVRVSEILRAACSAST-AT-HRAVRWQGLQVLRDVLESFADTRDPDFSEARLLEQFQAQLAAALTPAFGADSTPDVLAAAISVCSVYIIAGV--DASPTNRILRLLGSALEQTQSSEMSR--LGEL-PLTPNAA--AYLNIAVLTAWARLAIA--QRPAITNLLSPHVLARAWVHVLTAYAVLRADR--LAPLVQTHMLLYFAQAYPTLLHAL--TLVFETNPDVVRATLDAS----------FLALYGLALETLCDELDPQTEQSMLGVLSSLHVLVDAKYSGHF--LLEDAQFDELVCVFQRALLSEVLRVITLVRSLWRLLMHFIH-----CWQTLLDMVEVCGASLQELVAVSLHILVAFARRSLLTSALPVLRDLCKIMQGFMSAMISDALR-ARAGDIVSGNALVSTSLVLTCLDARVSISSEVIELLAQKL---ANDDAPVVLQCIRSMVHAEPSIGWCLPSLV-AYTLEPAMDILALRLAVPVAVQFVVVNRLMELAQTHAQAFRLATQALDEARTCLHDSLRAAV---DA--SISLRT Mellp23 VETPEDRGEVWLLQWLHLQNDLDASDEDALRASQTQIESDLVRL-LTPPPGRPIRNIIARILVKLFDRAEQRLFDVVGNLLR-V--AGTEPS-------EIMKVHGSQVMSQFAESVLTSLKVIKASSSLRYQALHCLNSALGSKTLTSSDNLAKDVLKTLRA-TLADKTYSIIRGTVECLLTLDIE-SYLVK--GLDTVDFVT-RRSL--SRLIANLLASASAKKKKDGSEEEMLALLSTPYSKT-TRRTRLGLID-AYGALLTLLGSTWVQYPEILQHIINDIGLISRKMALLRDIISVRLLSEQGQVVAIREIILNKW-PALMPTQPPSKYSLVIALNEVANLLQVGSAEVLYNPLIRLLGHPSSVQVAAALCLRYCYVAPIKLHTLELLNKDLAQLSNPAAP-PDTNKRAIGHAHGLAGLMSVISLRPLYVSFDVSS-KVMSVAIQLLKQCG-SHSLKISAFEIQVSWILVSALTSLGPNFV--KLHLSQLLILWKNALPKP-MAKD-ATNNRSDADFLLHIRECTLGAILNFLKHDGDKLVTLDVARRIVVMLNNALAFLGDKKYLQEHEQAPFADFLMRRRVFQCFNALAEAHQISLLDMTLSLMAAAISASTGSFTSVWDSNDGGFGVTGLGDRGLVSD-RDLTDSSIESNEHDMIDSAIELFALYLQMAILEKLYNHVTSMKLEKNPGRKMAILANSITAFLLSTRTCDPSVASLMKDVLKEGLVRTRAASAEAFGRVCALAGN-TFMVNQIQHCVTQIVNNTDPHSRSGYALCFSQIYTQVGSLSA-GVVLKTVVDILMSLSADPHPLVHFWALKALSEVIHTAGLSYSPFLNSTLGVVVKLYCLESG-STGYVNIRNLPTYQNF-CKILNAVIGVLGPELSSCGQAKILLQLLNEEEETDDGIK-VEALKSIQHFVMFSILIQTL-RKHL--------------------------------------------------------------QTADSNPTAWIDLCMRIVTTAQVKADEESQGLWRTQLFALQCLHEVFLTLIRSKKTE-HFSAQIARSKGLRVSDLIKMAFTAST-AS-IMEIRLEGLNVLRDVIENFKYSSDLDFDEAPLLEQHQAPIAAALTPAFSHDSFPEVLASAIQVCAVFVGSGVVKEIDKMGRMLKLLTSALESCRDTEIIS--LGEMKELSSTAS--VMIKTAVYAAWAEFQVTSVKQNYLCDVIKPHLLCPLWVASLREYARLKSDEE-QGGFTREIWLPYYESAWLKMMRAT--AYLIKAKEPFILRALDGA-DISRDEPAMFHVLLGLVYEAAALTASASSAAQVMETLIALEALLQSEVAGIHGLQKDSAVFGEICNLCYRLAATEVVRCIQLGL-CL--------IPSMSAFSACADLADRSQPESRRIYGVALGLFS--------GPVLPALKTLVEVLHGLLSQALVEDTR-QETTSQTSRNNLLACVLIFTSLPSGVKVSRTALELITVNIMSDEQETATTALHCAKSLILTKSRLTQLLPALI-DFLASEVLKTFTMSIFLPVYLMLLAVQHILSLASLDAIAFKEATNALEAQRTCLENALRGSIKS-TS-TSIALKS Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 --------------------------------------------------------------------------------------------------------------------------------------MVALRKMLAGRGA--TDLTNKEILKSLKL-TILDKALIMRSSSAECLTALELE-VSTIR--AMDESTFEI-RKSV--ATLIATLLYPPTGPKPAT---NELLSHLSAAYNKT-SREVRAGLSE-TYAALLIMLGPSVVHYGTILKHLLTELVLTVREHVLLRGVIGARLLSESGQIASIRELWLKMW-PAVMPGDEPSEYALISALNETSALLDLGGADILMSSLTNLVSHPSAVHTATAWCLRLCISLPTNLTLSAKLSTDLGTLNNNGNNFQDVATRANGLAYAIGGLITVISVHPLYVSFEMSA-RIFSMAAQLIKNST-NKEVRVAAAQIQIAWVLIGALMCLGPNFV--KMHLPQLLLMWKTALPKF-TSKD-ATNTRSELDFMMHARECALGSVASFLLHNGEKLVTVDVSKRVAALLSNTMAFATVPPQPAPGNKAPVHDDALRKRIFECFVAMFEVYHSTLIKAALDVFSNAISAAT--FTTVWAVDDGGYGVTGKRQEEILDGK-DSATPILGAPEHDVIDAAIELFSILLQGSMMDDLSKMLKNSTLDKNPGRKMAIQVNAVVALLGATKYAGPLASSLSQSILKDSIVYIRFVACEALGRLTSVLGS-LTVTNQIKYLMDQVVANRDPDARAGYALALGNVFSHLGGMMA-GGHLRSIVEYLTSLSRDPHPIVHKWSLHSLALTISSAGLMFSPYVSSTLTNVATVYLAGAG-SIATANIAELSVYHEL-GRIIYGLIGILGPELQSSAKVRELCVGLVEENEDDEFVI-VQGIRCTQHLIMFAPLVPFL-QARLRSTGLSLKKAAMTCMY-QLVQRDVKSVFQHSMGGLDDQFFKLLDTDPTL-QDVKDVVRSWITQTALEQPSQWIDICRKVLTNSNAAADDDNDNMWRTRIFALECIRQVIDVVSTSGIVD-HFDLAVARRKKRKVADLIKMTVYAAS-TP-IQEIRMEGLLLLRQTIEKFKETADPEVPDSVLLEQYQAQIGAALTPAFTAESTPEVVSLGVKVCAVYVGSGIIQEVDRFGRVLKLLIGALEKCKDKRLTA--VGDVTDLTPHAS--QMIKWAVLNAWAELQVASVHRNYLVAVLRPNLLCKLWANALEEYARSRIESE-YADSSKDTEKNFDQTSTLKILGAV--SSLVDEKNEFMVEALDAE-DKKSTESAAIHVVFGLCLEILAKTSSSQSAINLVVALLALHSILKPQFIEKE--FLGK-VFLEMMMILERVAWMEVVGVITVIQGIVQLLVELYLSTGSSVAEMLTVLVKVAPPKYQHLSAVTLNVLVSVLRDELGPLVLVNIKGVMEILNGTLGALL--------------KQAAFA-----------------------------------------------PGR-----PEVV-----STGF--------------------------------------VDSMESGAMAC------------------ Mucci2 -----EKQELYVLQWLAVERESKAVDVETLKKAQPIIEKTLFRL-IS-KPRRPIRFLIGRCYVILYTRGDTRLFDSVTALHS-L--IGANKNAAIATTGAIMGTSGGKILSLFAETALIFLKVLKSSSSLRLETITAFTLLLAGKAA--TDQILKDLMKQLRN-GLVDKALVVRIASAQCMQAVDIE-ALLFK--AFDNSTFPV-RRAI--SSLCATLLVDPSKPKHASTGEEEMLGQLSSCYNRA-PRELKTGIIE-TYATLFVLLGTEFVNYAVITKHILCEILAYLRSQVLLHYTIGKRLLSEQGQANAIRLLWIKKW-PPLMANQAPNKDILICVTNLVSELVELEGADVLVEPLFVLLTHTSSVQMAAVWCIRVCNALPTHLKSLNLLEKNLGNLTNQATT-VKVFQRTIAYGYTVAAIMSVFPAHPIYTSFELSA-RAMALANQLIKQT--HKDPKIASVQVQVAWTLIGSIMCLGPNLV--KIHLPQLLLLWKSALPKP-TGKE-A-NARSEPELLFHTRECVTGSIYSFLAHNSQSLVTLDIAKRIAALLNNTLAFLQT-----ATTMSPCTFYALRRRIFQCFITIYESSLSSLLRNSLTVFTHQVTATVGQFVSVWNTADGGYGVTSKSTD---SGKKDRFEPVIGSLELDYINASIELFATLFQESTFELMVKVVKDPKLEKNSPKRAAVLVNIVVALLGAFKNISPRATQLAQEILMEVVIYLRNAASETVGRLTSIVGG-SFVAAQMQLLVDLVVSNRDPDVRAGCALAIGYIYTHVGGMAA-AAHLKTIVGILLSLSSDPHPVVHAWALEAMAMTVSAAGLMFSGYVNSTLGMVAKLYLPGSG-SIAVTNAGGFTAYQEF-GRIIYELIGTLGPELQASSKVRELCLNMVEELEPDERVN-VEAIRCIQHFLMFAPLVPYL-QSQITSLHLPLKKAAVTCLY-QLVQRDSELVFKAAQPGLDTELFKMLDTDPQL-SDVKNVIRSWLQETAVAEPSIWVNITKRIVSGSAGAVDDDADGFWRTQLFALECLQQTIELIYASGIRE-HFDLILARKRRQRVPDLIRLSFTAAT-AH-VNELRLAGINLLKVVIERFSNTLDADLEDMLLLEQYSAQIGAALTPAFGADSSSEIVSAAVRVCAIYVGSGIVKDLYQLGRVLKLLISALDRCKESKLTG--VGEVKDLSPHAS--VMVKLSVLNAWAELQVASQKQAYLKQVLQPNLLSPMWLRALQDYARIRLESDIYSAATKDVVLPYYRRSWLKIMEAV--ATLIETNAPSMTDAI-------SN----FYILFGLCIESLSRISSYDNS-TIPI-LRALRTFVQPSLAGKQ--FVPKSVFLELMNVFDRLIQTEIIEIIRLIQSLLRLLINVFLVPKLSSLDTLALLVGITPKSYKDLLAICFYIFSEILTETLAPRVLVSLK------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MSSTPEQQELFLLTSVSLSRHVLTLEPDDCTAQQFYIKKEAFKV-LNPSPTRVIRNALGRCLAHVFDKGDRKLFETVNELVGIIS-SGKLKTAAVACLGDIYGSAGDSAIGLHQLVCSALLKLLKAASNLRAAVLTAFGKIVIQGSM--DENVARDIWKQGRNHASGDKGSLVVVAACRCLRSLDFD-KLKFK--TFDNPSSNA-RSAA--ADCFAQALVKKSKSKRQSTMGANILKTLSTQYVRT-TNKARAAIAI-CIGNVLQKLGEKTVNYLCILEILTADFLLISRRMVIIQDILGKRILGESGQITAAKAIILKNY-PQALKEKEPSKHTLVVSLSALSSLISLGTAEGCRDGLLQVLQHPSTVQVYAAACMKFVLACPQQLVCMNSLSRELSLLGT------NSPRRCIGFAHGLAAGLSASPQRPLYGSVEINS-RVLTMATNLLKSSG-TSELRVASTQIQVAWTLIGGLMSLGPNFV--KIHLSQLLLLWKNALPKV-LAKD---SMRNLLNFLTHVRECALGSILAFLQFNS--LLTVDVCKRIATMLQSTTAFLKTAKKTSSERLTPALEVMVRRRVLQCYTKLEALLQSNLLTLAISLFATSIANAAGTFDSIWEVGDNGFGVTSLPGQQTNGSDEYEPEPVCGTLENDVVNMAIQLFAFVFQESALEQITTFIRAGSLQRETGRKAAVDVNVVTALLSTLRVANMAVEKLLQELLRDFVLYVRSIAYEAIARLCSACGN-AFTNQEIKFLVDTIVVNREPSARAGCAMALGCIQTKIGSMAA-GYHLKTILNILMSLCNDPHPTVHYWALEAIARVSDAAGLGFSSFVSSTLGMLAKLYVPELA-SPITMNLEDLSSSAAI-ARCVDALINVLGPDLQDSTKSRELILTLVGYQEEDLEIQ-RASLACMEHLTLYAPYVRTL-QRYIKSDHAALRDVAVDSLY-NLMKRNSYDVIKAAEQGFEDHLWLVLDASPSH-DGMRNLIRNWLRQTCLSDTAAWLARFQHVLTNTGRSGDEEVAGFWQVTTFAMDCLNDIFILVTKD---------VATHG---KVADVVRMAFSAST-SG-VLDQRIWGLKIIGAVLKMFGKIPDPDFEEAMLLEQYQAQISSALTPAFAADSSPELASEAVDVCASFIATGIVTDVDRMGRILKTLVSSLENFADEDNAG--IGDLKGLSSNAQ--VMVKMSVFAAWAELQVASSEQKYLLDVLKPHILTPLWLESLREFARLRFEPDIYAALNRETLLKFYQESWLKLVDAI--ASLIEQDSEFVFDALDGK-ELSRDEPVAFFVLFGIAFEALATRPGATREQTL---LRALKKILHPSVSGHA--IYRDAIFSETMDLLDRLVLTEIVEIAALCVALTRIIVLVLSLPNLSSLNALVDAAEVFPSIIKDLHACILHIFATILATVIVPQNLSTLKRFINQLLGCLRRFLYLNAQ-KREAPTSVKNCLLAITILFTG-------GKNHLPLVAKFLVDCLTDTAKIAANCIRSLLLNTNASRHLLPRLI-AFVTSLIAQTLAMALVVPTLLSRATSARLLELASADQTAFRAVVGAMSEQRAFMEEVIKSGRGGRR--STIALKM Orpsp11 -----------------------------------------------------------------------------------M----------------------------------------KQSTDIRHEILDSLSRGLAGRAL--SESTAKDIFKLCKY-GFSDKSLIIRADSGNCLQALDYE-SLIIK--GMDKSNFKV-RQSL--SSSASYLLV-----KKSSSAPDEALSILYNAFNKS-SREILTGIIE-CYASFYQKMGIQWINYALILNHTLSLLKLIVSEYCLLRNVIG-KILSESAQNNAVKIIHIKKI----LSNKEEKDLEMKCVLDELAALLDLGPAE-VAKALNAVVSYPNAVNITAAWCIRFCKQNSTYIYFVNQLNNAESSLDE------NSLDNYISFCYPLATLITLIPQRSLNISIAMAA-QLFNYSNHILKSSS-NIPLKIMDAKIQVAWTIIDALMSLGPKFV--KVHLTQLLNLWKNALPKI-SMKD---NSYTEKEHQIDSRSYALSALHSFLEYNDNNLINIDISKRIVICLNNVLAFISSSNILSSSSSSPLKEYLMKKRLYQCYCKFYEMAQTILLKATLELIAGNISSHH---------------------------------SILAS------------------------------------------------------------------------------------------------SYTTSLIK-----------------------------------------------------------------------------------------------G-----------------------------------------------------------------------------------------IRVDVANHLG-------------------------LID------RGINNIVTS-------------------------------------------------------------DYDV--------RIEEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 MSSSEEQQELYMLTFTSLVQYISGLEAAEVTSQQKDLKKELFKI-LNPTITRVLRNNLGRCFGAILSKGDRGLFETITDLLAILN-AG--KSAAVHCLGEVFATAGDSAFMQSNVATLGALKLLKSASNLRAVIFAVMRKIVIGVPI--DEGTARDIWKQARNAALSDKSTFVQVNACRCLEQLDFE-QLKWK--VIDSPAAPV-RHAV--AAVLGRALIKKSKRKK----PPDLLRQLSSQYLKT-SNRSRAGICI-SYKYVLRNLGDKIVRYGQIATNLLVELLLMTRRFIILEDTIGQGLLRENSQLNAAKWLILKDY-PQVIQEREPSKYTLTSAVSALSSLISLGSADSCRDALLQVLPHPSTVQVHVAHCLRFVLASPHQLICMNSLNREIGQLGT------QSPRRCVGYANGLSAMLSTSRLQPLYGAVDVFA-RVFTQATDLLKTSS-TSELRVASIQIQVAWILIGGLMPLGPSFV--KTHLSQLMLLWKNALPKH-LGKE---NAPGTLEFLTHVRECALGSLLVFMEFNS--LITSDGAKRISAMLQNTVEFLDNKPKAMSQRLQPSLSTMVRRRVLQCFTKLDIISQSSLLSLAISSFAGSISGSAGQFDGLWDLCDNGFGVTGLSGTQEDDKSLDSVDPISQASEHDVVNSAIDLFSVALQESSVEQIATFLSSPGLQRNPGRKAALVVNISVALLHTLKVA-PSTDKILQELLQKFVIVVRTIGAEALGRLCDSAGN-TCTNTQVNWLVDTIVENREPNARAGCAAALGCIHAQIGGMAA-GLHLKTIVGVLMSLCNDPHPVVHFWALGGLERVANSAGLTFSPFVSGSLGMLAQLYNEEAA-ALATSNIESFLTPVVI-SRCVDSLINVLGPDLQDIAKTRNLILTLLRQLEENPALV-TESSKCLDHFSMYASYVKRL-QTELRATNFIMRDVAVRGLN-NLMKRDASSVMQTVGQSLEDDIWLAFDEAPDN-KSLKSMIQDWLQQTALTETEMWIQRCQNIMTPAVQTADDEVAGFWQTRNFAMGCLSELLATVQEA---------ILPDS---NVGDIVRMAFSAST-AN-VIELRVWGLKIIDQVLTMFGKTPDPDFAEASLLEQYQAQIGSALTPAFAADSSAELASEAINVSATFIATGIVTNVDRMGRILKLLVLGLENFSNPETTE--IGDLKGLNSNAR--VMVKLALFSAWARLQIASIDHDYLTPVVQPYILTPLWLSSLQEYARLRFEPDIYAALNRETLLKFYQDTWLYLVDAI--AGLVEKDIDFVFDALDGKLQPPREEPVAFFVLFGLAFESLV----SAS-QRL---LQALKRILRPVISGNA--IYQDAIFTETMDSFDRLVLTEIVEIANLSLDLTRSIILVLALPNLRALRSLVDVASVFPSIIRDLHACILHIFATILATGVVPQALPIFRQFVHQLRGCLTRFLLTIAQ-RRESDISAKNTLLAITFLLTA-------GAHVIPVLIRVLLDCLQDLATVAASCLRSILVKP--GRHLIPRLI-AFMVTVVARTLATSLIMSALLTRASAGHLLELAKADQLTFRSLVATMDAQKSLLEEVLRSA-ASKTG-ASIALRM Phybl2 ---------------------------------------------------------------------------------------------------------------------------------LRLEAINTFTLLLAGKAS--TESILKELTKHLKN-GLVDKALVMRVSSAQV--SVDVE-VLLFK--SFDNATFPV-RRAV--SSLCATLLVDPNKPKYATTGEEEMFGQLSTHYNRS-SRELKIGLVE-TYATLFVLLGTDFVHYGVIVKHVLTELLAFTRSQVLLHNTIGKRLLSEQSQANAIRLLWVKSW-PPLLPNQPPNKHALICAANLISSLVELEGADVLVEPLFTLLTHPSSVQMAAVWAIRVCYSAPANLKALNLLEKNLANLANPNSK-TKVYRRTIAYAHTAAAIMSVFPSRPIYTSFELSA-RAMSLANQLLKNT--NKDQKIASVQIQVAWTLVGSLMGLGPNLV--KLHLPQLLLLWKMALPKP-TGKE-A-NSRSEPEFLFHTRECATGSIYSFLEHNSQSLVTLDIAKRISALLNNTLAFLAT-----ASSVSACLYYALRRRIFQCFVTIYEASLTSLLRNSMSVFTNQVSASVGQFVSVWSSTDGGYGVTSKRNDDNNSGKKDRFQPIIGSAELDYIDSSIELFATLFQESTFEHIAKVVKDSRLEKNSPRRAAVLVNVVVALLGAFKNMSGRATQLVQEILMEAVVYLRNAASETIGRLTAIVGG-SFVASQMQQLVDLVVTNRDPDVRAGSALAIGYIYSHVGGMAA-AVHLKTIVGILLSLSSDPHPVVHAWALEAMAMTVSAAGLMFSGYVNSTLGMVAKLYLPGSG-STAVSNAGGFTAYQEF-GRIIYELIGTLGPELQSSSKVRELCINMVEELEPDERVN-VEAIRCIQHFLMFAPLVPYL-QSQITSLHIPLKKAAVTCLY-QLVQRDAEAVFKAALPGLDNELFKMLDTDPNL-SDVKNVIRSWLKDTAVNDPSIWVNITKRIMSG-NGPS-------WRTQLFALQCLHKTIELISASGIRE-HFDLILARKRRQRVPDLIRLSFTAAT-AH-VNELRLAGIGLLRMVIEKFAMTEDADLEGMLLLEQYAAQIGAALTPAFGPDSSSEIVSAAVRVCAIYVGSGIVKDLYQLGRVLKLLTSALDKCKESKLVG--VGEVKDLSPHAS--VMVKLSVLNAWAELQVSSQKQDYLKQILQPNILSPLWLQALQSYARIRLESDIYSAATKEVVLPLYRRSWLKIMEAV--ATLIETHEPSMISAL-------SN----FYILFGLCIESLSRISSSNAP-TMII-LNGLKTLIQPTLAGNE--FVPKAVFLELMNVFDRLIQTEIIE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 MATHEDNGEMYLFQWLSAEKWLKKIDLEIIKSRQTDTEEILVKV-ITPSPGRALRNLVARCLVLIYTRGETRLFDTLGIFLK-V--AAEYKAAALYCVGELMAVFGAQFMSYMAETTTTTLKTCK-SSNLRYHALVALRKALAKKAV--TDALAKDMIKQMKY-ALNDKLLPVQRASADVLIMMDVD-AVVTK--SLENADQAT-RRSL--AALVGHILSDAAQKRSNTK-DGEMLAQLSTHFNKS-SRKTRIGIFD-FYAVLLNKLGSSFVNYALIVGHFMSEVVMLVRNLVVLRDLIGVRMLSEQAQITAIQELYLKRW-PAMMPGQSPTPLVLVIVLKEVAELLQLGNTDAVSEPLVTLLSHPSTIRVGAAWALRFCYSTPLRLAVMEMLQRDINSLVSPAAP-SDVNLRALGHAYGLSALVSVIPERPLYVSYDISA-KVLDMAIQLLKRAG-EHDLRIAGVEVEVAWTSIASLMSLGPNFV--RPHLPQLLVLWRNALPKP-TSKD-TTNSRSIQEFLLHVRESALGAILCFLRHNAAPLVTLDVARRIASLFTNALLFANATQGVAPTDVPE--EALLRRRIYQCFSALTEATQATLLQSAVSLFAAAIASSSGTFTSIWQSVDGAYGVTYISEDATGSSHRDTIEPILGAREHDVVDAAIDLFAQLLTSRTISSIVDSVNSNKLEKMAGRKAAVFVNASVALISYLRHANSQIASTLSSFLKDALVVLRVASSEAIGRLSSLAGT-AFLTNQIKSLVDQVVNNRDPHGRAGCALAFGSIYGHVGGLAA-GPLLKTTVNVLMSLSNDPHPVVHFWALSALARVINSASLAYAPFVPSTLGMLLKLYLVEGG-SLPNANVGDFPAYPVA-CRIIDAVITVLGPDIQESARTRTLVLNLVHEVEDDESIA-VEAIKCIQHFLMFAPLVTRF-REYLSSSRRPLKLASINALY-QLVQRDALSMSKLGGDRLVEDLFGMLDDDSSV-EGVRNVISSWLQQTVIHNPSAWIDLCQRIMTASQQ--DDEGESLWRTQLFALQCLHGICTIVAQSGRKE-HLDIPFARSRGLRVPDLIKMAFTAST-AY-VTEIRLEGLIVLQDVIKIFAKSPDPAYEDALLLEQHQAPITAALTPAFSADATPEILAAAVQACAVFVGCGIVTDISRMGRILKLLTGALEQAKDSGALS--LGDTGELGPNAS--AMLRISTLSAWAQLEVASAQQAYLSDVLKPHRLAPLWIASLRDYASIRADSEFYSSLGKEVLLPYYVDSWSIILQAV--ATAMQANDTHILAAMDGR-D--SEEPAAFFVVFGLVYEALSASSTTPSRLPTVIALQTLKCIVRPEYAGKA--LKDPATFDEFISLCYRMAMTELIDVATLASACLRICAYVIRTAASRAFNAFCTMGSAVHGTQGDIRAVGVLLYSELLQDDLAGPALPALKSLLTLVHGLLSACVIDEMR-GREGVISVKSNLLAAVLILTVTPPFIKLGRGVIELISQKLLEPNSQISLTAAHCAKTLIVAAASTKMLLPALI-EFIAGEVWKSFALGIILPTAILLLSVTQLLSFAALSPVSFKEATAKLDQSQERLEQSVRQQLAA-PA-TQISLRS Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 NEPSRDRGEIWLLHWLKLDSNIERAEESALKSLQAQLESDLIRI-ITPKPGRPIRHLVARILVQLFDRAERRLFDVIAALLK-V--AGTEPPASFHVVGELMKAHGSQVMSQFAESVMVSMRVLKTTTNLRSQALFCLNCSLGSKTLSPSDNLAREILKTLRY-SMTDKTFSIVRGSADCLLTLDIE-ACLFK--SLEGVDFDT-RRSL--SKLIASLLATTNNKKNKEGQEEEMLSLLTTQYSKT-SRQARNGLID-AQATLFTLLGTNWVFYPEIMNHIIFNIGLVSRKLALLRDVISVRLLSEQGQIVAIREIIINKW-PALMPTHPPNKIALVIALNEVSGLLQVGCAEVLYNPLIRLLGHPSSVQISSALCLRYCLVAPGKLHVLELLNKDLLHLGHPGGP-SDAHKRAIGHAHGLAGLISLISLRPLYVSFDVSS-KIMSLAIQLLKESG-SHDLHISIVEIQVAWILISALTTLGPNFV--RTHLPQLLILWKNALPNP-AARD-SNNIRSDAEFLLHLRECTLTLILSFLQHDGEKLVTLDIARRIVMMLSNALAFISEKRYPQDQEPPVFAELLLRRRVFQCFTALVESLQMTLLETSLALFAAAISASTGSFTSVWDSIDGSFGVTSLSVDSLMTD-RDLAEPCIESNEHDTVDAALELFALYFQSMLIDRLSKFCHSSKLEKNPGRKMAILVNSVTAMLLAAKSCDPAVVNLMKDILKEALVRLRAAAAQTFGRACALGGN-TFMLSQIQHCVTQVVTNTDPDSRSGYALAFSQIYTQVGSLSA-GATLKTVVDVLMSLSADPHPSVHFWALKALSEVIHTAGLSYTPFLNSTLGMVVKLYCLESG-GVGYVNLRSLPSYQNF-CKILNAIIGVLGPELSSSGKSKTLIQLLNEEEETDEGIK-VEALKSIQHFMMFSILVQTL-LKHLSSNRRTLKVASINSIY-QLVQKNAMVMSKLGGDKLVVNLFSILDDDPTI-EGVRHSIKSWLRQTADSNPSAWIDLCMRIITAAQASVDEESQGLWRTQLFALQCLREVFLTVIRSKKVE-HFSVQAAKSKGFRVSDLIKMAFTAST-AN-IMEIRLEGLNVLRDVIENFKRSSDLDFDDSPLLEQHQAPIAAALTPAFSNDSFPEVLASAIQVCAVFVGSGVVKEIDKMGRILKLLTSALESCRESEITS--LGEMKDFSATAS--IMIKTAVYAAWAEFQVISIHQAYLSRVITPHLLCPLWVASLTEYARLKSDED-QGGLYREISLPYYENAWLKMMKAT--ASLIKAKNPIILQALNGV-DLSRIEPALFHILLGLVYEAAATTASSSITAQTMETLFSLDALLQIEVVGSEGLKKDNAVFGEICNLCYRLTATEVVRCIQLAH-CLRVIIQVLINPGMSAFTACADLADRSTPSSRQVYGVLLGLYSESLKDDLAGPTLPALKLLIEVLHGFITQTLIEDAS-RKLEEKSLRNNLLACVLVFTSVPPEVQISRAALEVLSRLFLNDSTEIGATALHCSKSLILNNKRLTRLLPSFY-EFIFAEILKIFALVIFLPLYLKVIGISLVLQLASLDSVNFKQAMNCLEAQKSSLESALRGSLSA-TG-PSIELKS Punst1 MASKKDGGERYLFQWLSTENALKDKSTDALKSIQNDAEAALVKV-IAPSPGRPFRNAVSRCLLHIYRTGETKLYDTIQTFLK-I--AGDVKAASLYCVGELMAEFGTQVMSLVSEVVNITIKIYR-SNSLRYHALIALEKTIAKRAV--TEATSRDIVKYMRQ-GLNDKALAVQRAASDVLIVMEVE-SLVVK--SLDGADQLT-RCSL--SRLVGHFLAEQKKTKDPKAGEVEMLHQLSTPYNKT-TRKARIGIFD-FYAATLTRLGSQFVNYTTIVQHFMSELVLLARRLILLRELIGDRLLSEQAQITAIQELYLRKW-PALMPGQAPPSQVLTIALKEVGGLLQLGNAEALAEPLVTLLGHPSTTRVHAAWTLKLCHAAPLRLSVMELLQRDITSITSPAAP-SDIDTRTLGHAYGLSALIAIIAEQPLYVSYDISV-KALDMATLLLKRAA-EHDVKVAGVEVEVAWTMIASLMALGPNFV--RAHLAQLLVLWRNALPKH-TSKD-AMS-RSVTEFLLHVRESALGAVLNFLRYNA-SLVTLDVARRISSLLANALSFANTSQPIEPPE----IETLLRRRIYQCFTALAESTQASLIQSTVSLFAAAIASSSGSFTSIWQSVDAAYGLTGL------TASRDTVEPILTSNEHDVVDAAIELFAQILCVRAVTQLLDSVKSPKLERNAGRKAAVSVNAAIAILMSLRVSSAQVTTALSPFLKDSIVTLRAAGSESIGRLASVAGT-SFLTAQIKTLVDQVVSNRDPYARAGCALAFGSIYEHVGGLAA-GPLLKTTVNVLISLGNDPHPVVHFWAVYALSQVINAASLAYAPFVHSTLGILLKLYTPEGG-TLNASNLSDLPVYQPA-CQTVDAVINVLGPDIQESSRTRALILGLVQELEEDEGIR-VEAIKGIQHFLMFAPFVLQF-RAHLGSSRRPLKLASINALY-QLVQKDALAMSKIGGDRLVEELFAMLDSDPSI-DGVRNVITSWLQQTVVYNPSAWIDLCQRIMTASQRAADDEGESLWRTQLFALQCLHAICSTIASSGRRE-HIDIPFALRQGLRVSDLIKMAFTASA-AY-VPDVRLQGLQLLRDVLEVFSRSPDPDYEESLLLEQHQAPITAALTPAFSADSTPEILASAVKACAVFVGSGIVKDVTRMGRILKLLTSALEQSKEDGTIS--LGDARDLSPNAS--VMIRIATVSAWAELAVASMHQPYLLDVLKPHRLASSWIACLRDYASIQAGSDMSFSLGKDVFLPYYRDTWSVILHAV--NIAMQTQDPFVLAAIDGR-EPSREDPATFFVLFGLAYEALATSSVQSTRQTS-IILQALKYLVRPEYSGTS--FLQTPAFQELISLCYRIAMTELVGMVELASSCLRICGQVLRIPGANGFDAFATVALTFGPAWTELRAVAVSLYNEFLKEDITSPTLQSLKSLLEVAHAILSSCLIDQMR-GRAGPVVIKTNLLAAVLILTVVPPTVKVGRPAIEIISEKLLD-EEEVSLTAVHCAKTLIVAASNTKMLLPGLV-EYVASEVVKAFALGVLLPTLALLLVVAQILAFATTDAAAFKDVTARLDQARDTLETAVRQAVAA--G-SQISLRS Rhior3 ----------------------------------------------------------------------------------------------------------------------------------MLETVTAFTLLLAGKAA--TEQVLKDLMKQLKN-GLVDKALVMRIASAQCLQSAEIE-ALLLK--AFENSTFPV-RRAV--SSLCATLLVDPAKPRHASTGNEEMLSQLSTSYNKS-SRELKTGLIE-TYATLFILLGTEFVNYSIITKHILVEILTYLRAQVLLHHTINKKLLSEHGQATAIKMLWVKKW-PALMANQAPSKQILLCVTNLIAQLIELEGADIVIEPLFILLTHPSSVQMAAVWCIRFSNACPSNLKSMNLLEKDLNNITNPATT-VKTYLRTIAYAYTTAAVMSVFPAHPIYTSFELSA-RAMSLSSQLIKQT--HKEPKIASVQVQVAWTLVGSVMCLGPSLV--KIHLPQLLLLWKSALPKP-TGKE-V-NSRSEPEFLFHTRECVISSIYSFLLHNSQSLVTLDIAKRIAALLNNTLAFLAT-----ATTLSPCVSYCLKRRIFQCFITLYESSLNSLLRNSLMVFLQQVTATVGQFISVWNIADGGCGVT------------------------NFVNASIELFATLFQESTFEMMVKVIKDPKLEKNSPKRAAVLVNVVVGLLGAFKNMSPRATQLLQEILMEVVVYLRNAACEAIGRLTNIVGG-TFVASQMQILVDLVVSNRDPDVRAGCALAIGYIYSHVGGMAA-AAHLKTIVGILLSLSSDPHPVVHAWALEAMAMTVSAAGLMFSSYVNSTLGMVAKLYLPGSG-SIAVSNAGGFTAYQEF-GRIIYELIGTLGPELQASSKVRELCLNMVEELEPDERVN-VEAIRCIQHFLMFAPLVPYL-QHQITSLHLPLKRAAVTCLY-QLVQRDSELVFKAAQPGLDNELFKMLDTDPQL-SDVKNVIRNWLQETAVAEPSIWVNITKRIVSTKNDPADDDADGFWRTQLFALECLQQTIELVSASGIRE-HFDLILARRRRQRVPDLIRLSFTAAT-AH-VNELRLAGIHLLRMVIEKFSNTPDADLEDMLLLEQYSAQIGAALTPAFGADSSSEIVAAAVKVCAIYVGSGIVKDLYQLGRVLKLLTSALDRCKESKLTG--VGEVKDLSSHAS--VMVKLAVLNAWAELQVASQRQKYLRQVLQPNLLSSMWLRSLQDYARIRLESDIYSAATKDVVLPYYRRSWLKIMEAV--ATLIESQSSPMLEAI-------SN----FYVLFGLCIESLSRISSGDYS-TIPV-LHALRTFIQPSLAGEQ--FVPKAVFLELMNVFDRLIRTEIVEIIRLTQNLVRVLVNVFLVPKLSSLDAFALLVSIAPKIYKDLLAIYLYILSEIFAENLAPRALVSLKSVIHVTGATVHALL-----------------------------------------------------------C----------------------------------------------------------------------------------------------- Rhoto1 PAPADGRGEIWLLSWLSCEKAIKVLPEATLFAEQANLTKALVAL-VTVKPGRPARALVARILILVFSRGDSKLFDVAQSLLRGM--NGSEAKASAYVLGELYAVFGSQIMSLYIELIQATTRIFRTTSSVRFSALVCLRKVIAAKSM--SDQTVKDVMKTLKA-GLSEKAGAIVRGSADCLLAMDIN-EVLFR--ALESADFTT-RRSL--SRLIAGILAAPKKKT---GKDIEMLVQLSGPYNRA-SRRLRNAIID-VYAELFKTLGSAWVHYADIAKHAIDELGVAARKAVLLGDVVSAQLLSEAGQISALREVYLKKW-PSLMPNQGPSKQALLLALEETTSLLSLGCADVLYDPLVRLVSHPSSVQITAAWTLRFCNAAPNRLQLLELLNKDLSIISSDGPN-K-VHRRAIGHAHGLAALVNLIPHKPLYVSFDLSA-KCMSLAIQLLKQSG-NHELHVSGVEIQVAWILVGSLMSLGPHFV--RLHLPQLLILWRNALPKV-TSKD-ASAARGDNEFLLHIRECTLGAILSFLRHNGPSLVNEDVARRLVMLLSNGLAFSTSTAHPNSAEHQPSTDIMFRRRLLQCFVAFTQQYQIPLLQQAVQLISQA-VANSGTFTSIWDETDGGYGVTNLSANNKLAK-RDAAAAVLEAGEHDVVDASLELFSLYFQSALLQILHNNLRSFKLEKNPGRKQAMLVNCVTAILGALRLAAHQVASPMRDLIKEALLSLRQAAAESLGRLSSLGGT-SFMAGQIQFCVQQVVSNTDPDNRAGCALAFSEIYSHVGSLAA-APVLKTVVDVLLSLSADPHPLVHYHALQSLSNVIDAASLSYAPFTNITLGVLCKLYMPEGG-TPGSVNLRDLPAYQAM-CRVTDALIGVLGPELQDSERVRELVLILLKEMEKDDGIA-VEAIKATQHFLIFAPLVSNL-RSQLSSTKQPLKVAAVNSVY-QLVQRDAALMSKLGGDGLVRELFALLDDDPTV-EGVRDAIISWLRQTADANPSGWIDLCQRIMADLASKTDEEAQGLWRTQLFALQCLHEVFATVIKSGRRE-HFDV--ARARVLRVADLIKMAFTAST-AQ-VMEIRLEGLVVLKDVIDNFAASQDVDFDDALLLEQYQAPIAAALTPAFAADSYPEVLASAIQVCAVFVGSGVVKEIEKMGRILKLLTSALESFKESDMTS--LGDVKDLSTTAA--VMLKTSIFAAWAQFQTSSVNQPYLAEVIRPHLLCPFWVASLREYARVRTDPV-YSGLSRETALPFYERSWPQMLHAV--ATLLKASNPHMLRAIDG-----RSDPAVFWTVFGLSFDALCTAPSNSAGTTIQTVLDALGGLFRPDVAGTA--LNDEGLFDEVCNLCLRLALTEVLDITGLVQLCLRIAVAAFRVPATSVFSRFADVADLLPAQLRELYAIAFHFYSVLLKDDFAAPTLPVLKTLCDVLNGVLSACLIDAVR-VRKSTTALRNNLLAVTLLLTTLPHTFQVGSEVVELVSEIALDTASESSGVALNCVASLLLAASRASHFVPAVV-ELVADEVLKAFSLSVILPSLVLLLALNHLLALATSLSLHFKEATAALPEERKLLEDSIRAAVKG-RG-GRIELRM Rozal11 ------------------------------ACHRARCESILRDV-----------------LLLFITYGETKLYEFCNSLLDLL--TGAFKL-VLSVLGSVMEKVGSRVSTIGVEACI-----------VRIESIETLMKTLVGKAI--NEGIHKDVFKVMKG-LMSDKNAQVRISAANCLNSLEVE-NLVLK--CFDESELF--RKAL--AKMIGNILADKKKKK------IEMLNLLYTPISKGLSHETCMGLIE-IYSVLFSILGAEIFEMTMVISHVLSFLDENMRESVIMKSLCLNS--TEPFKIKMIQCV------GELLKQNELNDDQIVCVLNQVSLLFELDSLEGIIEPLFNLLVYSSVVQVNGARCLRLVSAQPSLLRLLNMIEKDMFNVVD-----SKLLHKLYGHVIGLASILNVVNKKPLYISSDLIL-RIISKCMNLLKK---KEASNVLTVQQTMAWILLTPLMALESNFI--KIQLVQLMLFWNSIFSKN-EALP-----TNEEHRYISVRLASLTCLNSFMFHQK--LMNLELTKRISKIVENAL------------NVTPKVNYLLVTRLFQCFSNLFESSATRLLQVCLDTFLYCLAKIN---------------------------------KFQTSYENDVINESIKLAARVAQESCLNALLQNLKNGKENEE-------------KILLFFSIFSNKLIELSQELIQMFILMIRCIACEILGKLVKVNGQNEFTSNLIKTLVDQLINNKDCVAKGSFGLAIGCVMRELGSMTV-GAHVKTVIGILMSLSSDANEIVSVWCLHSLSITIESSGIYFEEYLNPLMNLLNKLWF---------------TNYEMM-SKLLLSLIGMIGPELITIVD-KCLIMM---DFNQNESII-NQGLLILQQIILFAPIIPII-QTKMLNKNNT--KGCVTCLR-QLIQRDYKSVLKYSNY-LINQFLAFLKDEN---NEIKETLIILCKFISIEDPFLILEISKNAQ-------NVKPENVWKTLVFLIQLL---------------QISL--------KIHEFIKVSFNAST-SV-SDSLRLQGLLLLEDILLKFSLIEDPEFAGHSILEQYQAQITSAITPVFSSDVIPEIQSIGIKICSVYVSSGVSKDISTLGRILKPLTNCLDKIK---------G-----------------------------------------------------------------------------------------------------------------------FYLIN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MSSTSEQAGMYVFQWLCTEKAISRVAMEDLKAGQSDLEKTLVKI-IAPLPGRPVRNVVARCFIALYRRVETRLFDTLQGFLK-I--VGDFKTAALSVTGDLMAVYGSQFMSFVAEIITLTLKIAK-SSSLRYHALLALQKTVTRRAV--TDSAARDIFKQMRN-TLTDKALPAQRAAAAVLTVLEIE-AIIVK--SLEHADQPT-RRSH--ALLVAHILAEPSNKKNNTEHDSEMLARISVHFVRT-SRKTRIGIFD-FYVALLQKLGPAFVNYAAIVAHFVSDVILLVRSLVVLRDLVASRMLSEQGQIGAIQELYLRRW-PAMMPGQAPHSAVLVMALRAVAALLQLGNADAVAEPLMTLLSHPSSVRVTASWALRFCYTTPLRLTAMEFLQRDLTSITSPAAP-SDINLRTLGHAYGLSALIAVIPERPLYVSYDVSA-KVLDMAIQLLKRAG-DHDVKIAGVEVEVAWTLIAALMALGPNFV--RPHLPQLLVLWRNALPKP-TSKD-AANSRSAAEFLLHVRESALGAIYCFLQHNAGALVTLDVARRVSSVLSNALNFANGGQNIEPSEQDNGLEALLRRRVYQCFSALAESTQTTLLQSTVSLFAAAIASSSGTFTSVWQSADEAYGVTFKDEESLQGKKRDSLEPIIGACEHDAVDTSIELFSRLLTVRIVTELLEYARSPKLEKNAGRKAAVFINSAVAIVMTLRVISAQVTSLLSPFLKDALIVLRSCGSEAIGRLASVAGT-TFLTNQIKQLVDQVVNNRDPYGRAGCALAFGSIYTHVGGLAA-GPLLKTTVNVLMSLSNDSHPIVHYWSLNALARVINAASLGYAPFVSSTLGMLLKIYMREGG-SINNANVSEFPAYPFV-CQIIDAIITILGPDIQESTRTRTLVLNLVHEQEEDEGIR-VEAIACIQHFLMFAPLVQQF-RQYLSSTRRPLKLASINALY-QLVQKDALAMSKLGGDKLVEDLFGMLDDDASV-EGVRNVISSWLQQTVILNPSAWIDLCQRIMTATQQSADDEGESLWRTQLFALQCLHNICTVVARSGRQE-HLNAVLARNRGLRVPDLIRMAFTASA-AY-VMDIRLEGLTVLRDVIQIFATSPDPAYEDALLLEQHQAPITAALTPAFSSDTTPEILASAVEACAVFVGCGVVKDVGRMGRILKLLTTALEQSKDPGMLS--LGESGELSPNAS--AMLRIATVSAWAQLEVASVSQVYLKEVIKPYRLASLWIASLRDYASIRVDSEAFSGLGKEVLLPYYAESWAIILQAV--ATAMQSGDPYILLAMDGA-EPKRSEPTMFFIVFGLVYEALATTSGAANRRTIVLALQALKCLVRPEYAGKA--ILDPPIFEEFISLCYRIALTELIELVTLADTCLRICSHILRIASARAFAAFASIASSVKTTQRDVRAVAILLYNNLLKDDLVPPTLPALKTLLDTIHGLLSACLVEEMR-GREGPAVIKNNFLAAVLVLTVVPTSVKIGQPVVELLTEKLVE-TSELSLTAAQCARTLIGAAASAKLLMPGLI-EFVAAETWKAFLLGVLLPTIALLLSVVQLLAFATTSQVAFKDAAAKLEPTRELLEQAVRRAVSA--A-QQISLRS Schpo1 -----DKRETIYIDLLNYEKQLRNLNKN---TREDSLQTNLNPL-LS------TRKLLSNCIIALLKGLEGYQHRVLLYFVDSI--------NVLSVLTSCLEEYGNQINQQ-----ETFIRFFKYSKTVRSIALDGLSKCISIQST--NEDLIKEIWKCIKS-NLNTSSTNVLLSALRCAYYIELE-WFKFKKSSIDNSLL---HSSL--GRCFSAL--DENNENRSTTRRRHALRILVENYHSAKYESSKAVLVF-AVKHLFLMQRPSFVNYTTIVDIILLHQSLSSLEQYLFRDVIGRRFLDQSSELQGIEILVLEPY----LKDQKISEIAVKTAMASTADILRSKGSSQLLDTTLQILYLGKSLKNEVAWLLRLLSVMPSPLALFNRLELEFKHLRSEVSP-KGIFNNL---TLSLMSIYVAAEENPLYVASSIFS-KLFNFSLDLIKSSS-KLDLLAAQAQIKTGWRLLSAYVSFGPSFT--RMQLSQLLILWKNALSRV-PSKIHS---QNFMEADMFNRFEALQCLLSFLEYNK--LFTPDVRKRVIIFLNNCLKFYKATKRLE--------RSLLLARIFQCFFELMSLDDQELLSTTVSTIAAKAFTSPGIGSRFYAQPEEEFQTT----------------YICES-SSDLIDNAIQLFASMFMESTLEIMVASVTNLKSGRDILRYKAVTANTLFSIYGFLSAFPDKVVSLMIELLENLTAKLIPYISKSYAFLAYLYQ--SKPTSVLDTIIKRAAESGDPNCRAVLILAVGHILKKVGSGVP-QTTLITAYQLLKVFNTDSNDLVRECSIRASSVSLGSIAKTIPSVLTAQTRILLSYMLPECDIDVQLLKKRLFFPSTLF-ANYLDCLINELGPNLRSDSSTSHFAFDLAHQRDTGDNI--IHVYKCYQHLYLFTPFIREL-CGNIIDLKQPRREISIEVLY-QILLQNHEFSESCYKRHFDRLIWQSLDTTPDN-KLLKNILYIWLNDYKDSDIHSWVNILLFLVTSSSERSDEDTVSLWQTQFYAATCLKTCISEVMAENKEP-------------RISDLVRAAFVLST-SD-NFYLKQGGFELLDTIITDFSNVMDPDFDDVSLLDQFQAQISSAFSSAFVDDSSPEIVAMSLNIASNFIGTGLLKTESQAAKILNLLKEALESSL-PERAG--FEENRHFKYDSK--YFLRIATLSAWASLLVHSANVSYLKEFLSSNILSSHWIMALRGYSRLQFGPSLVQSINPKILLNIYEKSWLNIAESL--TILLSTDANLIYGILSGD-ELSASNRYSNFFLFSVCFQSLLIPST----------MRIMTEVLTEELCTKV--LYDHNVFPEVVDLLVRLILTEIVIFVKLALALVKILTLALTVPGLRCFNAFLDVSNIFPAIVRDLFATAMHVYEVIMDDNSKQELLAALRKLLSLIYTLFEHLLINDSD--------NETAFMSMVLVLT-------LAAPILDVVHDFLFSSLKSDFALRTRCVTSLMLVNSKCRFIIYKSV-----TEFIPALFLSMSIPIAAHFSIGEKLLKIMAIQPDEAKAIIQQLSPQKKCVEEILIQNV------------- Sorma MSSTPEQQELYLLTSVSLSRHVLALEPDDCTAQQFYIKKEAFKV-LNPSPTRVIRNALGRCLAHVFDKGDRKLFETVNELVGIIS-NGKLKAAAVTCLGDIYGSAGDSAIGLHQLVCSALLKLLKAASSLRAAVLTALGKIVIQGSM--DESVARDIWKQGRNHASADKGSLVVVAACRCLSVADFD-KLKFK--TFDNPSSNA-RSAA--ADCFAQALVKRSKSKRQSTIGADILKHLSTQYVRA-TNKARAAIAI-CIGNVLQKLGEKTVNYLRILEILTADFLLISRRMVIIQDIIGKRILGESGQITAAKAIILKNY-PQALKEREPSKHTLVVSLSALSSLISLGTAEGCRDGLLQVLQHPSTVQVYAAACMKFVLACPQQLVCMNSLSRELSLLGT------NSPRRCIGFAHGLAAGLSASPQRPLYGSVEINS-RVLTMATNLLKSSG-TSELRVASTQIQVAWTLIGGLMSLGPNFV--KIHLSQLLLLWKNALPKV-LAKD---SMRNLLNFLTHVRECALGSILAFLQYNS--LLTVDVCKRIATMLQSTTAFLKTAKKTSAERLTPALEVMVRRRVLQCYTKLEALLQSNLLTLAISLFATSIANAAGTFDSIWEVGDNGFGVTSLPGQQTNGLDEYEPEPVCGTLENDVVNMAIQLFAFVFQESALEQITTFMGAGSLRRETGRGAAVNVNVATALLSTLRVANMAVERLLQELLRSFVLYVRSIAYEAIARLCSACGN-AFTNQEIKFLVDTIVVNREPSARAGCAMALGCIQTKIGSMAA-GYHLKTILNILMSLCNDPHPTVHYWALEAIARVSDAAGLGFSSFVSSTLGMLAKLYVPELA-SPITMNLEDLSSSAAI-ARCVDALINVLGPDLQDSTKSRELILTLVGYQEEDLEIQ-GASLACMEHLTLYAPYVRNL-QRYIKSDHAALRDVAVDSLY-NLMKRNSYDVIKAAEQGFEDHLWLVLDASPNH-DGMRNLIRNWLRQTCLSDTAAWLARFQHILTNTGRSGDEEVAGFWQVTTFAMDCLNDIFVLVQKD---------VATHG---KIADVVRMAFSAST-SG-VLDQRIWGLKIIGAVLKMFGKIPDPDFEEAMLLEQYQAQISSALTPAFAADSSPELASEAVDVCASFIATGIVTDVDRMGRILKTLVSSLENFADEDNAG--IGDLKGLSSNAQ--VMVKMSVFAAWAELQVASSEQKYLLDVLKPHILTPLWLESLREFARLRFEPDIYAALNRETLLKFYQESWLKLVDAI--ASLIEQDSEFVFDALDGK-ELSRDEPVAFFVLFGIAFEALATKPGATREQTL---LHALKKILHPSVSGHA--IYRDAIFSETMDLLDRLVLTEIVEIAALCVALTRIIVLVLSLPNLSSLNALVDSAEVFPAIIKDLHACILHIFATILATVIVPQNLSTLKRFINQLLGCLRRFLYLNAQ-KREVPTSVKNCLLAITILFTG-------GKNHLSLVAKFLVDCLTDTAKIAANCIRSLLLNTSGSRHLLPRLI-AFVTALIAQTLAMALVVPTLLSRATSARLLELASADQTSFRAVVGAMSEQRAFMEEVIRSGRAGRRKIETIALKM Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 EASASEKKELFLFQWLSLARDLNKSSLDTIKAGQADLEKTLLKF-LAPKPSRPIRRLISRCLVVIYMNGDSRLFDTLSAVQGMM---VNKKLAAVYCVGILSETHGGKLMSLFPETVTSLLKLYKNAKELRYETIVALTRSLAGKGA--TDVMVKDIVKVAKA-CVADKLPLMRIVSVELLQAVEYE-SLLMK--ALESANYGV-RRGI--ASFVATLLNATAKKKGAVAEPEEMLGLFCTLCTKT-SREMRVGIIE-AYAVTLKRLGVKFVNYATIVKNVVDMA-IFMRESALLRDAVG-KMLSEVAQVNAMKELWLRKW-PPVLGTDAPSEHALVCILNELAALLDLGPAGAVVEPLFKLVAHPSSVNLALAWCLRLSLALPSHLKMMALIQKDLVHLHG------EFLNRFIGYGNALAALISAAPSHTLYVSFEIMA-RIFGLSVQLLKSASVSKDYRAMAAQTRVAWTLIGALMCLGPDFV--RVHTSQLLLIWKNVFPKP-GAKD----NRTEAEYLLTSKEAALAALYSFMIYNPKEVTSTDVAKRIALFLNNTLSFMLA-----STGPLPPGESFLRRRLFVCFKVLYEMSYSLLLRAALDVFAQSLLTSLGSVVHVASTLGADRGIA-----------RDTDVQVPGSLENDTVDAAIELFALLLQESLMEQLISLTKYPGTKIPPGRKRAMQLNIMAAVIGVLKHVSGKVSVAIRDLVEEFLTVFRTLSCEVLGRLARIVGTATFVNPLIQNLVDNVVKNRDPDVRAGSSLALGYILSYVGGMAA-SSQLKTVVGILHSLATDPHPLVHTWALHSLWLVIESAGLMYGPFVNSTLSVAVKLLMITAA-AANEQGKNNNEVYPSI-GRILYALVGVIGPELQMSTKVRELCFSLYEENEEDPFVV-VEAIRCIQHFILFAPLIPFL-QLQLTGNYNTTRKAAVTCLY-QLTQRSPDLVLEAAVNNLEEQLFALLDDGTVR-DEIRDTLTNLLKHVAPERPSRWLDLCKSILVGAAPTVEDDDDIFWRTQGFALACLRQLLFVMRDTKVKE-HFDLGLART---RLADLIRMAFSAAT-AN-VNDLRLEGLKLLREILEIFAAALDPDYEDHALLEQYQAQIGAALTPAFANDSAPDVLSLACHVSAVYIGSGINRDLGTLSRVLRLLTAVMERFKDNANTS--AGQT---TPHAD--VLLRISIVTAWANLHIASFTHRYLEEVTKPNLLADLWMSTLQDYAKVKLDPDVYLEATRHVVLPFYRKSWLFIMQAL--TSLVDTQPDLFVKQLDVR-LPK------FYVLFGLCVEALSTT-GSEREETIMSKLESLKRLLTPVVVGHE--FLDPPMFLEVMNLFDKLVQTEVVQIAQIVLEVVKLLFDVFAVPTLSALDTLTVLTTSVGVREQELVPIAFFLYLAILSNDLAPRVLLYVKTCVDTLQSAVSTLLFDYEI-WTTTADSIKNGLLASVVIITSSPMLSHHPGNQER-LVKCLLRHFSELPLISLQCIRTLLVATAKVRLLLPLVT-AWLLEEGLKMLLLSIVVPVFIHFIACQTLLQVAAQHPQQFKVAIAGLKEQRDILQRGLQSVVRERDS-VKIALKS Sporo1 ------------------------------------LTTSLLSL-VTVKPGRPARALISRIFLLLLKRGDSKLFDLAQALLKGA--IGNDYKACAYCLGELYSIHGSQVSRSFSQLLFLSPPKGNSSGSLRYSSLACLHKVIAAKSM--SDQNIKETMKSLRG-GLAEKAGAIVRGSADCLLALEID-SILFK--ALETTDFVT-RRVL--SRLIAGILAAPKKKAKEGGGDIEMLVQLSAPYNRS-SNRLRNSIID-VYAELFKNLGSSWVYYSDIAKHIIDEVGLVARKAAILHDVISGQLLGEAGQIAAAREIYLKKW-PSLMPTQPPSKQSLLIALDETSAILSLGCAEALYDSLVRLVSHSSSVQISASWALRFCNAAPTRLHVVDLLNKDLATISSKTPP-SEVHRRVVGYAHSLAALINLIPHKPLYVSFDLSA-KCMSLAIQLLKQSG-NHELHISGVEIQVAWILVSALMSLGPNFV--RLHLPQLLLLWRNALPKP-TSKD-ASAARGDNEFLLHIRECTLSAILSFLRHNGPSLVTEDIAKRLVLLLSNGLAFATSTSHPSSSEQSPSTDILFRRRLLQCFVAFTQPYQIPLLQQAVTIFSQA-AANSNTFTSIWDETDGGYGVTSLTANSKLAK-RDAAEAVLQAAEHDLVDAGIELFALYFQNALLQIMINNHRSFKLEKNPGRKMAILANSVTAVVGTLRHSAHQVAGSMREIIKDALLSLRQAAAESLGRLSGLGGT-SLMAAQIQFCVQSVVSNTDPHNRAGCALAFSEIYSHVGSLAA-GPVLKTIVDVLLSLSADPHPLVHFSALRSLSHVIDAASLAYAPFTNVTLGMLCKLYMPEGG-TVGSVNLRDLPAYQSI-CRVLDALIGVLGPELQDSDRVRELVLILLKELERDDGIS-VEAIKATQHFLIFAPLVSNL-RSQLSSSKQPLKVAAVNSVY-QLVQRDAALMSKLGGDGLVRELFALLDDDPSI-EGVRDAIMSWLRQTADANPSGWIDLCQRIMTGTANAQDEESQGLWRTQLFALECLHEVFVTVVKSGRRE-HFDI--ARARAVRVSDLIKMAFTAST-AQ-VMEIRLEGLVVLKDVIDNFGQSQDIDFEEALLLDQFQAPIAAALTPAFAADSYPEVLASAIQVCAVFVGSGVVKEIEKMGRILKLLTTALESCKDSDMSS--LGDVRDLSSTAA--IMLKTSIFAAWAQFQTASVRQPYLANVIRPHLLCPFWAASLREYARVRTDPE-YSGLSRETALPFYERAWPQMLHAV--ATLLKTSDPHMLRAMDGN-SSSRSEPALFWVTFGLAFEALCSSPSSTPTGMVQSILEAVVGLIRPDIAGTA--LRDASLFEEVCNLCYRLAITE----------CLRVATTALRIPATSIFSLFADVADVFPSPMRELYAIAFHFFSLLLKDDLVAPSLPVLKALCDVLNGMMSACLIDEMR-GRKSASATKNNLLAAVLLLTALPNHVKIGQEVVELITELALDGEGEASTTALHCLVSLLIAASRVGQLLPGVV-EIVAEEVLKAFSMSIVLPTLNVLLALSHLLQLASTYSANFKEATGILPEQRKLLEESIRATVTG-TR-AKIELKL Stehi1 MSDDHDEGEVYVFEWLSTERALKEAPVEDVKSSQSTLESSLIKI-ITPPPGRPLRSLVAKCFVLLYTRGDSKLFDTLISCLK-V--VGDFKAACLYCVGELMASSGAQVMSFMTEIAILCLKTYK-SSNLRYNAVVTIRKALARRAA--TDSVVKDIIKQMKY-GLSDKALPIRRAASDVLAVLEVE-SVIVR--SLDSSDQVT-RHSL--ATLVATVLADSSKKKPEGE-DPEMFQQLSGHFNKT-SHKTRVGIFS-FYIALLTKLGPSFVNYAQIVHHFIYDVILLLRRLVTLRDLVGVRMLSEQAQIGAIQELYLKRW-PALMPGQSPSPHALATVLKEVAGLLQLGNAIALAEPLVTLLGHPNTVRVHASWTLRFCYSAPLRLNVMDLLQRDISLMTSQSAP-ADLHTRALGHAYGLAALVTVIPQKPLYVSYDITA-KVLDMAIQLLKRAG-DHDVKIAGVEVEIAWTCIASLMTLGPNFV--RAYLPQLLVLWRNALPKP-TNKD-TTSGRTLSEFLLHVRESALGAILCFLQHNSPTLVTLDVARRIATMLGNAFLFANASQHIEPETETP--EALLRRRVFQCFSVLPETTQNTLLQSVISLVAAAITSSSGSFTSLWQTFDGAYGVTGLSDVDSIGGKRDSIEPILQSCEHDVVDAGLHLFARLLASRTIGQLIEAARSPKFDKNVGRKAAAFVNANAAILLSLRQASHQMTSALSPFLKDALVNLRTLSSEAIGCLAGFADN-TFLATQMKALVDQVVNNRDPQGRAGCALALGAIYENVGSLAA-APLLKTTVNILMSLSKDAHPVVHFWALHALARVVNAASLAYAPHVASTLGMLFKIYMLEGG-TLLNANMGDLPAYQVA-CQIIDALISVLGPDIQESSRTRTLILDLVHQDEDDEGIC-VEAIKCIQHFLMFAPLITQF-RTHLNSSRRPLKLASIHALY-QLVQKDALLISKVGGDRLVEELFAMLDEDASI-EGVRKVISSWLQQTVIYNPSAWIDLCQKIMTASQQVTDDEGESLWRTQLFALQCLHDICIIVSRSGRKE-QLDIAYARQLGLRVSDLIRMAFTAST-AY-VTEIRLEGLIVLRDVIETFAKTPDPDYEDAFLLEQHQAPITAALTPAFSSDSTPEILASAIGACAVFVGCGIVKDVTRMGRILKLLTSALEQCKGSAMLS--LGEAGEGSPNAS--AMLRISTLSAWAELAHASQAQAYLKKVVGPYSLVPLWVAALRDYASIRAGAELYANLGKDILLPYYAEAWPMILQAV--ASAMDAHDPGVQAAMDGL-ENPRTEPTTFFVIFGLVYEALSVNSS-AQRSTLSLIMRTLKNLVRPEYAGTA--LLDGPIFDELISLWYRMAMTELLETVAFAVSCLRICAYILRTHVSRAFETFSSIATSFDAGMQEVRTVAVSLYGDLLKDDLAGPTLQSLKSLLALVHGLLSACLIDEIR-GRTGIISAKNNFLAAVLVLTVVPPSVKVSRGVVSLISERLAE-AQEMALTAAHCAKTLIAASSTAKLLIPGMV-EYLAGEVVKAFVLGILLPVLTLLLALTQLLSFASTSPAAFKEATAKLEPTRERLESSIRQALAS--A-QQISLRS Tapde11 -----EKQSLFLFNVLSQYQNLALLDATLIIAQSSTLLEGLI---IAPGLNRAHRNLLGRCFVTTFRRID-RPFETTTKILALL--------NAIVVLGIIFENIGDQIVSLVPELVNVLGRLTKSSAGIRAAAFNAIGAALTAK---LDDASYRDVLKYLKN-CLPDKSAVVYTAAYDCLNELNEE-SLQLK--NVEQITFKTVRSAA--SRCLASFYLEESEA-------ELMYRNLSTLYNKL-YRQVRSIVAV-TYQEILYRMGAAWIYHEQTMISVLNDLQLMTRRHVLLRQ-IG-DALDQEAQVVAINRM--------LAHIRAPSRHILVPCLMEITRLVTLGSADIEFDPIFFLMSHPVSVQVATAMTMKIVLNVPSLLNVFTRLKDELSTFSD-----AARNLDCLGLAFSLAALTSAGVQRPLYISLDKTAQQILNLANDTLKASS-KSTLHTASVQVQVAWTLVGALQSLGPTFI--RSHLSQLLLLWKNALPKP-LAKE-T---QSSGDFLFHVRETALSSIYAFLKHCR--LCTSDVIKRLSTMISNSLAFLQ-ATHVAPSPVEP--EAKLRCRVLACLLEVTEIEESGV--TALAAFAIHITSSLG-YTSIWDVCDNAFGIS----------------PVFDGIEHDVAEHGIHLFAGLFQESLLAQMATLLANAQAQRNPGRYTAVQINCLLAIKRTLTTE-AKSMSGMTELIVEGLSYVRRLAAESFGRLATLGGS-AMTTSQVNDLVDRIVKDRDPFVRSGCTTALGYIHKFLGGIAA-VYHLKSILNVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ------SVDSVVLPLLTLSPMAREAAVAVMAASLAALADLLQSL-MTDKPAIEGANAALDSL------------------------------CAL---------AAFATPV-LPDLISRLLKLARATATTRVKVVTALAAAL------------------------------------------SSE-V--------AKPLK-----ALFALKI------EPAFQKMVAG--ARTV---------------LAPNAD--QAALPNDAAGSL---ALLALPLEAAAAAVGRSVCTLAA-LAGRLSVPARAVAFAPFLWLKALVGASAPPHSP-----ALALGFVQPLVPLDALDILDDGSHPLLALPLVLDVVVAAL--AYAVSDNMPRATDTLAADRFL---AASN--LHLRSTAAVALARAATACS--------ALPLSS-TLFA--------------SQVQSLQQAHAQLLLGSATAAHAILAWSVAYPPQ------TSLPVPELELG-ASVTLSPYTTTASQPGADLLCQAGLLLLAGLATAAPRLAASMWDKAVPALRYLSSASPQAASPAAPAAAV----DLVTGASAL-SLLSGSHLSLAAQLPAAAIDGGASALLP---------GCTRL--------------AALG-----QLTSAVALFGVLFNKLQLVNHF---S--ALGQ---RTRAFVSN-----IASTLASANVVAALL-PLLKSPV-LVRQLAAAALGLLAAV--A-PEASSVLESL-EAALREGNSVHAAGCALALGYHHVALGSLQA-APLVGPSLRLLLAAAQAGSTHLHSWAAASLELVAANGSVALH--------SALDTLLPELG-IETAFAADS--LPASFAARVVGGLPIMPGAPSAAALPALRLVLD----AASRLASAWRPLIKGALQVVIMAPLRAAL-VGGMIVARGSLGPDALSTLE-QALQRLGGDLLGSDSVDLASQ----LHAGP------SPALLEAVL--SPDNAPALLAFLRTATSAAAAGAGERANGV------------AAVARMAAAAV---------------QLEPAVGMAFSLCT-SQ-LPELKVAGFGLLAVVLDVYGGVRDPQFDDMYLLQLSQAQIASALRSGFGVAAAP--------VVAAYLTSPAMAAAKDVARTLAPLVR-LQGELDS------LMQYPHCSSLAV--ALLKSAVLRVFADLHVQSLEAPALADVLEPLVLAVQWLGALRDTPVL---GFA-YTAPVED-------------RALPGLAPLAVPHAPMLWA--------EDRDS----------ADLLLG--SRPAD-----LRALASVLSLGVNSMV--------------VSRRCGDAG-----RLLPAWVALVADLIAPPPLFSPGVATALASAWPTMVKPAQVLLDSLPSLMVAAAEAGVLRSATTALVSVAAGL-------AAVACSVGPST--ARLAGCSLVLVPHGL---VA--LTA----------------------------------------ATLADAAAQG-MLAGALPVLAVYL---------------FRDVMERMPAAERQ---------AAQAA-AAISLSL Treme1 -MSSDEGADLTLLHWLRAEQAIESLPSDDLLPQVQPLHAFFLKILLPPKPGRPIRQLLTRCMVKLHHRVESRLFDFVQALTK-A--LSDGGSACWYCIGEIMREHGSNMMSFMAEISMTSIKVLR-NSNLRAYAVTTFSKSLAGKAL--PDGLHKELTKALRN-GLTDRALPVQRACAETFISLTLD-AIAVR--SLEHADHLT-RRSL--SLLLAHFLADRKAARDT---DLEMLRYLSTAYNRS-PRKLRNAIID-VYATLFTSLGATYINYAEIVKHLMDELVLSARDSVLLRDLIGVRLLSESGQVMAIREWYLKKWQSVPLPGQKTNKYVLNVALREIAGLLSLGNAELLAEPLVRLLSHEASVRLSASYALRFCAINPGQLILFTDINKDLGILGTPTAS-KDVSHRVIGKTFALSALIAASNSRPLYVSHDVST-KVFDLATSLLKKAG-DHDISVSMIEVQVAWYLIAALMSLGPSFV--KLHLPQLLVLWRNALPKP-TSKD-SSVGRGETDFLLLVRECALAAVLNFLRQNM-SLVNIDVARRLATLFSNTLNFVNGAEALRQAASPAGVEATLRRRVLQCFTALTESMQPALLQAAVTVFAAAIAAQSGTFTSIWQSTDGGFGVTTL------GDERDKIEPILGSLEHDVIDAGVELFSAIFQIQSLGTLSSHMRSSKLERNPGRKQAVVANTVAALRLTLINASTQISDMIKSLLQDAILAIRTAAADAMGSLSSLAGS-AYLSTQIQWLVDQIVNNRVPESRAGCAVAFGSIYSSVGGLSG-GPILKTIVNILMSLATDPHPVVHFYAMSALTKVVDSASLSYEPFIPTTLGMLSNIYLPEGG-SLGSVNLRDLPAYQVI-CRILHALIGVIGPELQEPGKIRSLVFLLVHEEETDEGLS-VEAIKCVQQFLMFAPLVQTF-RTHLASSRRPLKVAAITALY-QIVQRDAVLISKVGGNQLVEDLFGLLDDDPSI-VGVREVITSWLTQTAAALPSGWIDLCQRIMQGQASSQDDEGESLWRTQLFALVCLHNIVQAVADGGKEE-NFDPLLARRLGVRVGDLIRMAFSASA-AL-VEEVRLGGLVVLRDVIEKFSSSADPDFEASLLLEQHQAPIAAALTPSFGTDSTPEILASAVQVCAVFVGSGVVREVGRMGRILKLLTGALEQCKDGEMTS--LGEVHNLSSNAA--VMLKVSILAAWAELQVAAVKREYLKDVVRPYRLGPFWVGTLRDYAQLRTDPEM-AGVGRDVLLPYYEQAVPKILHAV--AISLSLSDPYLLSALDGQ-PISSPTPCAFYIVYGLAFESLVKSMS-----FLSCVLKAMTSLVHPRLSGTT--IFSGSFFDELCTVCYRIAMSEMVQLLSFIITILAILVFVLRIPSPEGFTALCKVIECVEMVQRELLAVGIHLFGDLLKDDLAGGCLGCLKGLLEVIHGLLSACLVDDMR-TRVNPVAIKNNLLAMTLVLTSLPTNVKLSRDVLEVMGQYLAD-RPELGLTAVHCTSTLLTASLRPISLLPPII-TFLAKETIKSLAFGILLPTLSLLLSTSALLGLAQNSPKDFREATLIMSPERTRLERSIRDAVGG--G-GGIELKS Trire2 -MSSHEQQDLFLLTFVSLRQHVLSLSADDCTAQQFYLKREIFQI-INPQPSRVIRNNLGACLAHIFGKGDRKLFETINDLVAIAA-GGKSKSAAASCLGDVFASAGDSAIGLHQLACTTLLKLLKSASNIRAAVFSALEKIVVEGSM--DEYISRDVWKQARSHASADKGSLVVVSACRCLKALDFD-KLEFK--AADSSSAKV-RNAV--ASCFAEALVKKSKTKRASTHPQDILKILAGHYVKT-SNRARTAIGV-CYGKLFRRLGERTVNYLSIVESLSVDVLLISRKIIIIQDVIGRKILGESGQTSAAESLVLKNY-PQALPEREPQKHTLVVALNAVASLISLGSAESCRDGLLQVLQHPSSVQVFASHCMKFVLACPQQLVCMNSLSRELSLLGS------NSPRRCIGFAHGLAATLSASPSRPLHGSLDVNS-RVLTMATNLLKSSS-QSELRVSSTQIQVAWILIGGLMSLGPNFV--KIHLSQLLLLWKNALPKP-LAKD---NTRSLLEFLTHVRECALGSILAFLQFNN--LLTVDVSKRIAAMLQSTTAFLKTSKKITSQRLTPALDRMVQRRVLQCYIKLEALLQSNLLTLAISLFAASIANAAGTFESIWDVGDNGFGITGLPGQNENAIQVRKSDPVCGSLEHDVINNAIQLFAFAFQESILEQIRTFASAGSLQRDLGRKAAINANLATAVLCTMRVANIAVERLLQDIVRDFVLYVRSLGYAAVARLCNVYGN-AFTNQEIKYLVDTIVGNREPSARAGCAMALGAIQTKVGGMAA-GYHLKTILGILMSLCNDPHPVVHYWALEALSLASDAAGLSFATYVPSTLGMLAQLYVAEIS-SAITMNFEELSTTAAI-ARCVDSLINVLGPDLQDANKSRELIFTLVGQEEQDVFVE-RAALGCLEHLSLYAPYVRLL-QKYLSSEHATLRDAAVDGLY-NIMKRDPRDVLREAEKGFEDLLWLVLDAEPSH-DGIRNIIRNWLHQTALTETSSWLQRFQAVLANKSTTGDEEAAGFWQVTTFAMSCIYDMFAIIAKD---------VAANG---KIADVVRMAFSAST-SG-VLELRIWGLKIIGAVLKMFGKTPDPDFEEAMLLEQYQAQISSALTPAFAADSSPELASEAVNVCASFISIGIVTDVDRMGRILKTLVNALENFSDNENAG--IGDLKGLSSNAQ--VMVKISVFSAWAELQVASSEQKYLLDVLKPHILTPLWLEALREFARLRFEPDIYAALNRETLLRFYQDAWLKLVDAI--ASLIEQDSEFVFDALDGK-ELSRDEPVAFFVLFGLAFEALATRPGATQEQML---LQALKKILHPSVTGHA--IYRPDVFSETMDLLDRLVLTEIVEVADLCVTLTRIIVLVLSLPGLSALNAIVDAAEVFPSIIKDLHACIIHIFATILATLIVPQSLAILKRFVAQLQGCLRRFLYLNAQ-KRETPTSVKNSLLATTILLTS-------GTNQLPLVARYLVDCLTDTAKIAANCIRSLLLQGA-ARYLFPRLL-AFVTSLVCQTLAMSLIIPALMARATSTRLLELAAVDQGVFRAIVGGLSSQRAFLEEVIRSGR------ATITLKM Umbra1 MPPATEKQELFVFQWLSVEHESKLIDVEILKKAQPKLEKTLLSF-VT-KPRRPIRCLIGRCFILLYTRAETRMFDTVVTLHG-I--ASAGKNAAITTIGTIMGTLGSNILSLFTETANILLKVLKNSNNMRLEALNAFTLLLAGKAA--ADPTLKDLHKFLKA-ALPDKAQVIRVAAAQCLQACDIE-QMLFK--ALEGSTFPV-RRAV--SSTLSAILADPNKPKRISTAVEQMLMQLSSAYNRA-PKELKAGIIE-TYAALFIQLGTRFVNYAAIVKHLFTELLAFVREEVLLNDVIGRRLLSEQGQASAVDVLWVKAW-PALMPNQAPNKQALITAVNLVSSLVELGGAPILINPLITLLSYPSAVQAASAWCLRVCTALPTNLTLFGLLEKDLSNLSNASAK-TDLFRRTIGHVHAVASVMSVFPTKPIYTSFDLSQ-RASSLAKQLLDRT--HKDPAIASVQVQVAWTLISALMGLGPNIV--KLHLPQLLLMWRNALPKP-TGKE-S-NSRNEAEFILHQKECVITSILSFLKHNSKSLVTLEIAKRISALLSNTLAFLTT-----PTTLSPCLNYLLRKRIFECFVAIYESLFSSLLRNSVSVFAVHVTAAVGQYVSIWNNSDGGFGVTSKHEQDENRSKRDRYRPIMGSLELDYIDASVELFATLFQEAILEQIIKLMKEQKGDKNSPKKMAVLVNVVVALLGAFRNISGRTAQICQEILQEAIVYLRNAASDALGRLVNVIGG-SLMSSQIQYLVDLVVNNRDPDARAGCSLALGYIYSHVGGMAA-GNHLKTIVGILLSLSSDPHPVVHCWALESLTMTISAASLMFSGYVSSTLGLVAKLYLPGGG-STAVSNAGGFTAYQEF-GRIIYELVGTLGPELQAISKVRELCMNIVEELEPDERVN-MEAIRCTQQFIMFAQLVPYL-QVQLSSFHLPLKKAAVTCLY-QLVQRNAEAVFRTATPGLDTELFSMLDTEPSL-IDVKDVIRSWLKETAVKQPSVWVNITKQVLSASISKGDEGAEDFWRTQLFSLLCLQECIELISASGGRE-HFDLILARRKRQRVGDLIKLSFTAAT-AP-VNDLRLVGINLLRTVIEKFAATADPDLEGTLLLEQYAAQIGAALTPAFAADSSSEIVSAAVRVCAVYVGSGIVKDLYQLGRVLKLLTSALDKCKDADITR--VGEIKDISPHAS--IMVKLSVLNAWAELQVATVHQDYLRQVVQPNLLSPLWLSSLKDYARIRLESDIYSAATKEITLPFYRKSWLKIMGAV--ATLMESREPSMMNAL-------PNEQGSFYVLFGLCIESLARVSSSDSTMTLSI-LNSLKTFIHPSLAGPN--FVPKAVFLELMNVFDRLVQTEIVNITRIVNELFRLLITIFVIPSLSCLDTLGSLVSIAPASYKDLFAICLYIYSEALQRTLAPKCLLSLKNVLEVTGAMIHTLLMTQNL-IRESNEIIKHSLLASTLLVTGCPQANLENRQSLDTLKESLQNRNTEIVLTAHQCLRNLVMLPSKTKRIIPHIIVPYL-EEAIKTL-------------IMKHVLSLASSNPALFKEAVSHMSPVRSKLETCVRNSVSMQRQ-QTIQLKT Ustma22 RAGAEDQGEIFVIEWLSAEQALTKADVDTIRSYQNSFESAILKL-ACPRPGRPTRRLLARCILVLFRRIDSRLFDILQNLIR-V--AAEDAKAALYILGEVFGSLGQQIMSLFNEIINLTQRVFKQTSHLRYHALITLQKTLAGKSL--GDQVGKDLIKALRQ-GLSDRAGAVVRGSADCILAIEVE-TLVLK--AIESADFVT-KRAL--SRMLAGLLAAKKSSKKEGTADIGMLDQLSLPFLRT-GSKGRSALLD-VYATLFETLGSSWINYAVILKHLIDDLPLNVRTGVILRKLIGERMLGEQAQVLAIQEIYLRKW-PALMPEQPPSKTTLSLALAEISGLLQLGSVDAAYDPLIRCLAHPSSVQVQAAWCLKLCQVSPVHLAVLELLNRDLTTLANRGGS-VQLSKRANGHAQGLAALISVIPQRPLYTSFAISS-KVLSLAIQLLKNSG-NHDLNVSSIEISVAWTLVGSLMSLGPNFV--RLHLPQLLILWRNSLPKP-TSKDTAPGPRSDAEFLLLVRERTLSSILAFMLHNGSSLITLDTARRLVALLSNTLAFADGAQNPHLQEYTPAAEFLLRRRLFQCLTVLMEPMQAGLIKTTIQAFAAAIAASAGNFTSVWEMADGAFGVTSLRACSLIAQPRDLVEPVLGAAEHDVVDAAIQLFTSLLQVAAIEAMLAHTKSTKLDKNPGRKQAVQINVVVAILGALRVANDRLSSAIKDLLQDALLALRAAASEAYGKLAAVAGS-QALSSQVQFLVDQIVGNRDPDARAGCALAFGSVYKEVGGLAA-GPLTKTIVNVLMSLSNDPHPTVHYNALEALHVVIDSASLSYSPYVASTLGMLVKLYMPEGG-SAGSVNLRDLPAHQAV-CRVVNALIGVLGPDLQESTRVRSLVHCLLSERESDPGVV-VESTRALQHFGLFAAWIEQL-RKQLTGKQRTLKLAAINAFY-QLVQREALAMSRIGGDQLVEEFFAQLDEDPQL-DGAREVILSWLQKTADLAPSGWIDLCQRIMIDAADKGDEEAAAIWRTQLFALRCLHQVFVTVRQAGKLE-HFSTAGEKGQALRVVDLIRMAFTAST-SA-NVEIRLEGLVVLRDVIESFKLARDPDFEDALLLEQHQAPIAAALTPAFLADSTPEVLAAAVQVCAVFVSSGVIKEVSRMGRILKQLVSALESCMQPSMTQ--LGDVKDLSQNAN--AMLKIAVFTAWAELQTASATQSYLVDVVKPHVIVPYWIACLREYAKIRSDPEMYAGLAREVVLPYHERSWYTILQAV--TGLLHDNDARAFAALDGE-TTPRSEPCLFFVLYGLAFEALATRSSSLQQGTVMRILRAMTSLSRPQVAGSA--LLQDTLFSELCNLWYRLVMTEVLETIGMAASCLRVVVCVL-VRTTRAYSAYIGIVGLYAKALQDLFAVGFYTFAEMLKDDLVGPTLGSLKDLCEAIHGFLSQALVDDLR-TRAGRIATINSLLATVVVLTSIPINIKVSQAVAELIVQKVLQFEEETGLTAVNCARTIVLACSRVGQLLPGLI-EFVCEDAIKTFALAIVLPTLVVLLTVRQLITLAGQHAAAFKEATASLDARKALLENAIRAQLSR-GG-ASIVLKS Walse1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDKSYPIQRVSTICLLNLDIE-YFAVK--AAEVVDQHT-RQYH--TELVAQLLAQQSKLKRQTQKKDEMLKILSPVFTKG-QRKIKLIVLE-VYARLFLIMGSSWVNYQLIVNHLICNLMLTIRSSLIFRDTIGKTLLSEQGQVIAMNVLVLSKT-SVSSPTQGYSDNSLVVAIEETVGLLQLGSVDKLPDVMFKLIAHPASVQVATSRLFRFHYLCPTFLKILDLLEKKLSHLRTPNAA-SNVAFNSIGYACAVSSLIGLFKQRPLNTPIEIPH-KVFELSQSLLKLSG-ECEFDQASIHIQVAWILIDSLMSIGPQFT--SSILNQLLLLWRNSLSKV----D-LQASKTQIEFLSHIRECALSALLAFLKFNASELLTMDLSRKFTNMLINSLTFSIASAHMDNDQIPSGADILIRRRIFQCAVYLQTDSLTSLVEAAFNEFGATIASNTGSFASIWNVGDGGYGLTSL---------ND---PSPTAYEHDVVDASITLFALRLMVRLFDSVRASVKNPKLDRNPGRKLSILVNTLVAIVGFLNNGVAPIRNTLQELFEYAIVSLRRLGAEALGKLIALTADRTFLTSQSRYYMDLIVNNRAPSIRCGSAITLSAIYKQVGSLAA-GPLLNTIVDILTSLSSDSHPEVHYYSLEAFQTIVEAAGSAFSPYITRTLGLLASIFNPEGGQTIISNNIREYTLYKVL-CSILDAIIGILGPELNEMTEVRELLFLLVKQKEKDNVVK-EKALKSLQQFAMFAPLLKTF-QSALKSSNKSIQNSAVNGLY-QIAQKYVKEISQIGGDSLAENLFGLLDQEPGH-DGIKLLLLSWLRQTAEINAQGWLSICQKVFTKGINKQDEEVQGLWQTQLFALECVHHLL------GNKT-SKDAVAARS---RVAELIKLAFIAST-SR-VEAIRIKGLIILRDVIEVFAEFRDSHDNDASLLEQHQAPITAAITPAFGQDSTPDILALAIQVCATYVRSGIVKDVSKMGRILKLLSGTLSQFKSNTSIQ--IGEMKNLCITAK--KMLRVSTLTAWAELVAAYPIRPHLGEVFEPFWLIPLWAEIIENYAEIR--------LVQQILLPYYDQNWMKILNAF--VTSLDKKPELAKEFIDGA-KKS------FQIIYGLAFSTLVTEYE----------LNTIGMLIKTPGSDYW--ILEDNFFEELLELVWKLTIKSILGLLKMSKFCLQLIYLILSSSVLNAFITYLDVSDSLAATTRELFAVVLHKYAELLKRHIAAVLSPCLKVVLDTIHGFISFSLIDEIK-LREGPAIRKYNLLAIVSLLVSTPDHISLSKEVVEILCDCLLSNDKEMTGVVLGSFNKL------TVYLLKKLV-----EELPDEVLYNNIIPACVKKIASNCLLSMASKDALAFKAATARIDGDRKVLEATMRDTVNVNEA-SSISLKS Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3261.fasta_al_trimmed; alignment length = 127] Allma1 MVILQAYAHRVVV----LATE-AGRILVFVQVLGRLCGGKGGFGSMLRAQGGRMSSK-KTTNDSCRDLS-GRRLKTVKDAKLMTEALE-----KIAEKEAEREARIADATYDRE-HKQLVGSIRDAA Ashgo11 ------------------------------------------------------------------------------------------------------------------------------- Aspfu1 NVLLSSFTVSFSLPSTSLTTT-SNKQLLPLRLTVPLRGGKGGFGSQLRAAGGRMSSK-RKRNGSSRNLD-GRRIRTVNEAKALAEYLAVKPEMDRKEKEERRRRWQADGQWMED-KEEMNEKAREAV Aurde31 NVFISTFTYALSVPSETLSHP-SVQLRVTLRLAPAVRGGKGGFGSQLRAAGGRMSSR-KTGNDSCRDLS-GRRLSTLKEAQKLATYMEAEPDRKKAAADARKAKLAADTKFLEE-TQELVEGVRDAV Batde5 QVIIKPFTQCF-FPDHV-SSI-TSFSLLVLAVVPIMCGGKGGFGSMLRAQGGRMASK-KPTSDSCRDLS-GRRVKTVNDAKALAAYIEKEPERQRLKNEKIAQKIEKDPEFEND-HDDTMDLVNNAV Botbo1 SLLLSTFTLTLSAPSDTLSLA-RSAGPVTLRLAPRILGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLN-GRRISTVKEAKKLAEYLESEPQRKQATAEAQRAKLEQDTEYLEQ-SREIVDNVKSAV Botci1 NVLLTSFTLSLPLPTTTLTTI-SNKLLLSLRLSARLCGGKGGFGSQLRAAGGRMSSK-RKKGGSSRNLD-GRRLRTVNEAKALAEYLAIKPEMAKKDKEERRKRWEQDGKWVED-KEEAGERTREAV Caeel ------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------- CocheC53 TVIVNSINIAFATEKNALTTN-SRRSVLSLRLTVPLCGGKGGFGSILRAQGGRMSSR-KKK-GSSRNLD-GRRLRTVTEAKALAEYLAIKPEMEQREKEERRKKLEDDGQWVEN-KEEAENKTREAI Coere1 -------LVFLDIPDNSITGR-HGISVPWLALRGRLLGGKGGFGSTLRSQGNRMSAN-KSNNDDCRDLY-GRRLRTLKEAKGIMDKLDMEEKAKEEAAENRRKKIADDTPYMRK-CEEIVEETKKTT Conco1 QILVQIPNSSFFIPLTSLSSS-N----QTIQVNFRGKGGKGGFGSMLRSQGGKMNSQ-QTTNDSCRDLS-GRRLKTIKDAKKLVEYQEQQAELEKEKKEKIKEKIE-DDKYIEQ-TKQAVSGVKSAV Conpu1 TILFSTFTLSLSVPSETISPH-SGAIPVTLRITPRLHGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKEAKKLAEYLENEPARKKAAAEAQKAKLEADTEYLEQ-SQELVDNVRSAV Copci SVLVSTFTLNLLVPSSTITTQ-TGYAPVTLRLAPRILGGKGGFGSQLRAAGGRMSSQ-KTNNDSCRDLS-GRRLSTIREAKKLAEYLESEPERLAAKAEAQKAKLEADSEYVEQ-TKELSENVKSAV Croqu1 SVILSSFTISFSLPPSTLSTS-SGTSIVHLRLVPKVLGGKGGFGSQLRAAGGRMSSQ-KTQNDSCRDLT-GRRLSTIKEAKKLAAAIASEPERQAAQRREAEAKLIADSKELEQ-SKEGIEKVKSAV CryneH991 TVFLNFPSLQLQLPSTTLRTK-SSGPLITLHVVPRLLGGKGGFGSQLRAAGGRMSSG-KATNDSCRDLS-GRRLGTIKEAQRQAELLESEPALRAQAQAAEKAKLEADNKFLEE-SREINDSVRSAV Crypa2 NVLITSFTLCMPLPSSTLTTN-SNVELLSLRLTHPLCGGKGGFGSQLRAAGGRMSSK-RKKNASSRNLD-GRRLRTVTEAKALAEYLAIKPEMEQKEKEQRRERWTADGKWVED-KEEAVERTRSAV Debha1 ------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------- Dicdi DVLIRLPIINFKIKDKELKLV------KVYDLLLRVNGGKGGFGSLLKSSGTKVGQK-KTTNDACRDLS-GRRLRHVNNEARIKQWLEDEEARKIAMQE--------DTQFQKE-TEDIHKKVSNSV Dmel ------------------------------------------------------------------------------------------------------------------------------- Enthi QVTYHGISQYFNIPRQYYEGH-NGEVL----LIIRAHGGKGGFGALLK--GKEIKSK-KKENDMSRDLNTGKRIRTEKE-------LERKEERQVELKEMKIKKEKEDILLTENTTKKLLRKIDCYM Falba AACLESGRMRLCCPATGLALRGAASAL---------IGGKGGFGSMLRSQGGKMASK-ATTNDACRDLS-GRRLGDIRNEQARRERAE-----ILAALERERQQREADADFHDE-RQALEDRVSDAV Fomme1 TLLIDTFSLALTLPSETLTLP-SGSLPISLRLVPRLRGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLN-GRRLSTLKEAKTLAAYLEFEPERKKAQQEAQRAKLEKDTEYLEQ-SRDIVDNVKSAV Fusgr1 NVLITSFTLVLPLSPSTLTTL-SNKQLLSLRLAVPLCGGKGGFGSQLRAAGGRMSSR-KKKSGSSRNLD-GRRLRTVNEAKALAEYLAIKPEMEKKEKEKRRERWEQDGQWVED-KEESSERTREAV Galma1 SILIQAFTLSVSVPPSTLSTH-TGHVPITLRLSPRVLGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKEAKKLADYIEGEPARLAAKAEAQKVKLENDTEYLEK-SHELKEGVKNAV Ganpr1 TAFVSVPLVSVSFDFRGLQTR-GGAALAFFNLLLRLRGGKGGFGANLRSQGGRMSSQ-KTSNEACRDLQ-GRRLKTLNDAKK--------------------------------------------- Gloin1 SVIVTLFTMCLTFPTDALYTT-SGKLLVNVNLRIRILGGKGGFGSMLRAQGGKMASQ-KTTNEACRDLN-GRRLRTVNEARRLADHLEQEPERQRAQREKVKKKIEEDTAYLKA-SEEMKEKVQNTV Hisca1 NFLLTSFTLSFSLPSTALTTT-DNKQLIPLRLSAQLCGGKGGFGSQLRAAGGRMSSR-RKGNGSNRNLD-GRRLRTVKEAKALAEYLALKPDMDKKAKEARRKRWEADGAWMED-KEEVGEKAREAV Klula1 ------------------------------------------------------------------------------------------------------------------------------- Lacbi2 SILIQTFSLTLSVPNDTFSTH-AGHVPVTLRLTPSLLGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLT-GRRLSTIKEAKKLAEYLETEPERLAAKAEAQRAKLEADTEYLEQ-SRELSEGVKNAV Lenti61 SVLISTFTLALAVPSETLTPT-SGVVPVSLRLVPRLRGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKEAKKLAEYIESEPLRKKAQQEAQRAKLEADTEYIEQ-SREIVDNVKSAV Malgl1 --MCEPYTVKISLARSTLTSR-GGHSIVDLELRVRHLGGKGGFGNMLRAQGGRMSARGKHESDSCRDLQ-GRRLGSIKEAQLLAEYIAKEPDRKAALDEAQKRKYAKDHEYVEQ-SREIVDNVRGAV Mellp23 SILVSTFTISFSLPQSTLSTS-SGRSIIQLRLVPKVLGGKGGFGSQLRAAGGRMSSQ-KTQNDSCRDLT-GRRLSTIKEAKKLAAAIASEPERLAAQRRENEAKLVADSKELEQ-SKEGIEKVKSAV Mnele ------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------- Morel2 EAIVSIFSVAITFPEDSIQTA-GGLPLKYFTLSMRMAGGKGGFGSMLRAQGGRMNSQ-KTTNEACRDLS-GRRIKTVNEAKKMAEYVRGEPERKRARKEEIVLHGNT-------------------M Mucci2 QAIISLYPLCLPLNTNNLRTC-SGHSLLNIQLSGRMLGGKGGFGSMLRAQGGRMNAQ-KTTNEACRDLQ-GRRIRTVNDAKKLQEELDAIPEREAEKREKLKKKIEEDNKFLED-KEDVVENVKSAV Mydma ------------------------------------------------------------------------------------------------------------------------------- Neucr2 NVLITSITLTFALPATTLTTN-SNKQLLPLRLSLPLCGGKGGFGSQLRAQGGRMSSK-RKKNGSSRNLD-GRRLRTITEAKALADYLAIKPDMEKKEKEKRRKRWQQDGKWVED-KEELDERTREAV Orpsp11 SFILNLIPLCINVNYSPISTY-SGKYLQITNLSISVLGGKGGFGSMLRAQGGKMSSK-KTTNESCRDLQ-GRRLKTINDATKLVEYLNKESERKRKRKEEIDKKIEEDMEYFEN-HDKIIENIKGAV Pench1 NVLLSSFTLSFTLPSTALTTT-NNKHLLPLRLTAPIRGGKGGFGSQLRAAGGRMSSK-RKRNSSSRNLD-GRRLRTVNEAKALAEYLAVKPEMDKKEKEERQRRWQSDGQWMED-REEMSEKTREAV Phybl2 QAIVNSFTVCVVFDTLGITTV-GGHLLAIFNLSVSLRGGR---SAILPDPTSFIQEDELLEHKKCRLNE-PTSLESSSQSKKINERPTNTPEKTKGKERETRKRKQR-------------------- Picst3 ------------------------------------------------------------------------------------------------------------------------------- Plicr1 SILFSTFTLSLSVPSDTLSSH-SGVVPVSLRLTPRLRGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKDAKKLAEYLENEPARKKAAAEAQKAKLEADSEYLEQ-SRELVDGVRSAV Polpo NLQVRATLI---VIDSTLKGF------MYIEMMFGVVGGKGGFGSLLRGNSTRVGQK-KTTNDACRDLN-GRRLRHVNNEKRLKEWYESEEARKAALEQ--------HDDYMQE-DEEVAKRSQDAV Pucgr2 SVLVSTFTLSFSLPKTTLSTS-NGKSILLFRLVPKVLGGKGGFGSQLRAAGGRMSSQ-KTQNDSCRDLS-GRRLSTIKEAQKLAAAIAAEPERHLAKRKEAEEKLEGDSHLLTQ-SKEGIEKVRNAT Punst1 SIFVSAFTLTLSVPSDALSTL-RGDVALSLRIAPRILGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKEAKKLAEYLESEPERKKAAAEAQRAKLEADQEYIEQ-SRDIVDNVRSAV Rhior3 QAIVSLL-ICLPIEEKTLSTV-GGIALLYFNLSARLLGGKGGFGSMLRAQGGRMNAQ-KTTNEACRDLQ-GRRIRT--DARR--------------------------------------------- Rhoto1 PVLVQLYTLSLALPAATLSYA-SGRSLVTLRLGVRLPGGKGGFASQLRAQGGRMSSN-KAQNDSCRSLD-GRRLSTIKEAQKLAKLLESEPDRLAAAALVKQQKLDEDAHYVEE-SREIVSGVKDAV Rozal11 QAYIEFPHL---FNFNELKTS-LGLYLTCISVMPSLLGGKGGFGNRLRSQGAKMSMI-KTTNEACRDLS-GRRLKTIHDAERLARHILEEPERKQKEKEKLKKKIEKDSEFLDQ-SRITQSRIEEGV Sacce1 ------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------- Schco3 NLLISAFTLTLAVPPNALSTA-RGVLPVTLRLSARLLGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLN-GRRLSTIKEAKRLAEYLESEPERAAAKAEAQKAKLQADTEYLEQ-TRELTDGVRSAV Schpo1 TVFLN--SVNVNLNRLALTHQ-SRIVHLNLTLCTRVLGGKGGFGSQLRAAGGRMSKK-RNEQDSCRDLD-GNRLGTIRQAKELSEYLAKKPAETRAKKEAKKQKLNKDHEYLED-LEQSVSNVRDAF Sorma NVLITSITLTFALPATTLTTN-SNKQLLPLRLSLPLCGGKGGFGSQLRAQGGRMSSK-RKKNGSSRNLD-GRRLRTITEAKALADYLAIKPDMEKKEKEKRRKRWQQDGKWVED-KEELDERTREAV Sphar RSVLVSFTSCLPVAEAVLLNV-AGESF-------ALKGGKGGFGSMLRSIGAKAAQR-RNGGLTC-------------------------------------------------------------- Spipu1 QVIINTFPLCLQFPDDSLTTE-GGRSLPVFNLLLRLPGGKGGFGSMLRAQGGKMASQ-KTTNEACRDLS-GRRLKTVNDAKKLADYLEKEPERKRKRQEELMKKIEEDPEFVSS-HEKVMEDVKDAV Sporo1 PVLVSLFTLSLSLPATSLQYS-TGQSLVFLRLSVKLPGGKGGFASQLRAQGGRMSSN-KAQNDSCRGLD-GRRLSTIKEAQRLAKLLESEPDRQAAAAKAAEAKLEADTKYVEE-SREIVSGVKDAV Stehi1 TVLISTFTLAFSAPSDILSPL-SGILPVSLRLAPRMRGGKGGFGSQLRAAGGRMSSQ-KTSNDSCRDLS-GRRLSTIKEAKKLAEYLESEPDRKKAAAEAQKAKLEADTEFIEQ-SKDIVDNVRSAV Tapde11 ------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------- Treme1 AVFLRLPPRQLNLHPSTIRTA-S----ISLEVCARIRGGKGGFGTQLRAAGGRMSAG-K-TNDSCRDLS-GRRISTLKEAQRQAELLESAPAIKAAAAAAEKAKLEADHAFLEE-SREINENVRSAV Trire2 NVLISTFTLVLRTAPSTITTT-SNRELLSLRLAIPLCGGKGGFGSQLRAAGGRMSSR-KKQKGSSRNLD-GRRLRTINEAKALAEYLAIKPEMEKKEKEKRRQRWEEDGKWVED-KEESNERTRDAV Umbra1 QAIVNTFPLCLGFNPDGVTTL-GGKDLIVYNLSIRMIGGKGGFGSMLRAQGGRMNAQ-KSTNDACRDLQ-GRRVKDVNDAKKLAEYLESLPEREKEQAEKLKQKIEKDNKFMED-REQVIEDVKSAV Ustma22 PVLVESFHVCLSLPASASLIH-QGRRLV-LQLRALLPGGKGGFGTLLRSQGGKMSAGARNSNDACRDLN-GRRLGVLKEAKKLAEYLEGESERKRQMDEAQKIKYAKDSQYIEQ-SREIVENVRSAV Walse1 ----------MKCSKD-----------VDVHVTPRMLGGKGGFGAQLRSAGGRMRSN-RNHNDACRDLS-GRRISTLKEAQKVADYLESSEEREKKLKQEKLDKVEADDQFFEK-NKDMNDNVRSSV Zygro1 ------------------------------------------------------------------------------------------------------------------------------- [Cluster3266.fasta_al_trimmed; alignment length = 40] Allma1 KARTLIVRLLSSAGTGYFYP-KLSLRKYDPVVKQHVLFNE Ashgo11 KSKTTVVRLVSTALTGFFRP-LVTQVRYDPVAKRRVLFRE Aspfu1 ---------------------------------------- Aurde31 ---------------------------------------- Batde5 KARTLVVRLISTAGTGFTYP-KLQLRKYDPVVNQHVLFIE Botbo1 KARTLLIRLVSTARTGYFYP-TMSRMKYDPKAPRHSLWLV Botci1 ---------------------------------------- Caeel ---------------------------------------- Canalb1 RANTTMIKLVSTALTGYEKP-KLNLILYDPRAKRHCLFKE Cangl KAKNTVVKLVSTALTGYSRP-LVTQVRYDPIAKKHVLFKE Capow ---------------------------------------- Catan2 KARTLIVRLLSSAGTGYFYP-KLALRKFDPVVKQHVLFTE Cioin KSARILVRCVSMAGTNNSIP-KAVLLRYDKAVQAKVLFVE CocheC53 KSRTIMVRLISMAMTGYYRQ-PLSMLKYDPIVRKQVLFLE Coere1 KARNILVRLISTAGTGYTYTYRLNMMKHDPRVNKHVLFKE Conco1 KARTILVKLLSSANTGYFYD-KLSFMKFDPRVNKHVLFTE Conpu1 --RTMIVRMVSTAQTGFFYP-RLSAVKYDPQVGQRVLFKE Copci KARTLIVRLISTAQTGFFYP-KLSAVKYDPVVKRRVLFVE Croqu1 KTRTVLVKLVSTAGTGFFYERKIARMKYDPRVNKHVLFTE CryneH991 KARRILVKLVSTALTGSFYE-KLAKIKYDPIVKKHVLFTE Crypa2 KSRIVSVRLISMAMTGFFYP-PMSMLKYDPVVRRKVLFLE Debha1 KTTHTMVKLVSAAKTGYEKQ-KLNLILYDPVAKRHCLFQE Dekbr2 KARTTIVQLISTAKTGYRRK-EVTQVRYDPIAQRHVMFVE Dicdi KISTVIIKMVSSANTGYFYTKKLLLRKYDPVIRQHVLFKE Dmel ---------------------------------------- Enthi ---------------------------------------- Falba KARTIIVKLLSTAGTGFFYDYKLNFVKYDPVIRQRVLFKE Fomme1 ---------------------------------------- Fusgr1 KARLVHARLVSMAMTGFFYP-MMSMLKYDPIVRKKVLFLE Galma1 --RTIIVRLISTAQTGFFYP-KLSAVKYDPKVKQRVLFVE Ganpr1 KARTVVVRLYSAAQTGFFYP-KLSLVKYDPVVKQHVLFNE Gloin1 KARTTIVRLVSSAGTGYFFP-KLSFVKFDPKVGRRVLFTE Hisca1 KSRTIAVRLISMAMTGYYKR-PLSMLKYDPVVKKKVLFLE Klula1 KTKTTVIKLISTAMTGVSRP-LVTQVRYDPVAKRHVLFKE Lacbi2 KARTLIVRMISTAQTGFFYP-RLSAVKYDPKVKQRVLFVE Lenti61 KARTIIVRLVSTAQTGFFYP-RLAAVKYDPRVKSRVLFVE Malgl1 ---------------------------------------- Mellp23 KTRTVLVKLVSTAGTGFFYERKIARMKYDPRA-------- Mnele ---------------------------------------- Monbr ---------------------------------------- Morel2 KARTIIVKLLSTAGTGFFYA-KLSFMKFDPRANQNVLFNE Mucci2 KARVILVKLLSTAGTGYNYP-KLSLMKYDPQVKQHVLFTE Mydma ---------------------------------------- Neucr2 KSRIINVRLISMAMTGYFYL-PMSMLKYDPIVRRKVLFLE Orpsp11 ---------------------------------------- Pench1 KSRTIAVRLISMAMTGYYRR-PLSMMKYDPVVKKQVLFLE Phybl2 KARVILVKLLSTAGTGFNYP-KMSMMKYDPVVKQHVLFNE Picst3 KTTHTMVKLISAAKTGYEKP-RMNLILYDPRAKRHCLFTE Plicr1 KAKTLIVRLVSTAQTGFFYA-RMSAIKYDPRVKAHVLFVE Polpo KISTVIIKMVSLANTGFYYTRKLLLRKYDPVVQQHVLFKV Pucgr2 KTRTVLVKLVSTAGTGFFYERKIARMKYDPRVDRYMPLTS Punst1 KAKTLIVRLISTAQTGFFYP-KLSAIKYDPKVKQRVLFVE Rhior3 KARVILVKLLSSAGTGYNYP-KLSMMKYDPMVQKHVLFTE Rhoto1 KSRTILVRLLSTVGTGYSYERKLAFMKYDPRAGRHVLFTE Rozal11 ---------------------------------------- Sacce1 KSKNSVIKLLSTAASGYSRP-LVTQVRYDPVVKRHVLFKE Salro ---------------------------------------- Schco3 KARTLIVRLISTAQTGFFYP-RLSAVKYDPVVKSRVLFVE Schpo1 KAR-LLVKLLSTAGTGFFYP-KLAFIKYDPKIHKRVLFEE Sorma ---------------------------------------- Sphar ---------------------------------------- Spipu1 KARTVVLRLLSSAGTGFFYP-KLQLMKYDPIVNKHVLFVE Sporo1 ---------------------------------------- Stehi1 KARTLIVRLISTAQTGFFYP-RLSAVKYDPRVKQRVLFVE Tapde11 KARNILVKLLSTAGTGFSYPYKLQMIKFDPRVNSRVMFEE Thetr KRKTVIVKLVSAAGTGFYYQRPLAFRKYDPV--------E Treme1 --RRILVRLVSTALTGFFYE-KLSMMKYDPKVKRHVLFVE Trire2 KARLINVRLISMAMTGFFYP-MMGMLKYDPIVRKKVLFLE Umbra1 KARVLIVRLMSSAGTGFFYP-KLSMMKYDPKVQQHVLFNE Ustma22 KARVVIARLVSTAGTGFMYE-RLSMMKYDPKVRKHVLFKE Walse1 FYRTVLVRLISTAKTGFFYE-KLSAMKYDPKVKQHVLFVE Zygro1 KSKNTVVKLISTAATGYFRP-LVNQVRYDPVAQRHVLFKE [Cluster3274.fasta_al_trimmed; alignment length = 151] Allma1 PALLVLVAAIFIEVVSWIGFSLISEQLFALYRWLRT-SALQAELVDLRRDLKSMSAMDEFAKWARTRRQIDAKVAEYEKLSSTLRTTAQVATRAVFYLLYLFIYRATPMFFIPDDWF-SGLLGAALSLPF-APAGSVSVMVWVLACRRVTR Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 LILTIFFVHVAIYLVNTVGATTIDTLLWILYLKLQQ-SRLKREVVQLKREMNNTSSQDEFAKWAKLRRKHDKAMDEYEAMNKKLTAQVKIARWLSTNGLKIFLYSKTPVFALPAGWF-PFYVEWVLSFPR-APRGSVSVQVWNSVCATAIA Aurde31 LALAIFVMVLITQIVSWIGKSVLSDAACVVYLNVRQ-RQLKADILHTKAELLQTSAQEEFAKWAKLRRKVDKGLSDLEALNKGLVSTFQTVLWVLTSGVQFVIYGREAVFFVPAGVL-G-PLTWWLSIPF-APRGSVSCMVWQFACQRVIK Batde5 KLVYILAVAWIFQAISTIGFDYISKLLYEWTGLLKL-QQLKKQILDLKTQLGSISAQNQFAKWVKLQRQHDKLVTEYTAKANNVNLHVSWGLWALFWILQIGFWRSDAMFYMPKTWV-G-PFSSWLSFPF-APAG---------------- Botbo1 LLFTIFLLVFVTELISWVGQSVLHDSACAVYLRLKQ-NELKASILASKQELLQTSSQDQFAKWAKLRRKVDKGLADLERINSELASAFKTGLWLLTGGAQFFVYRKQPVFFLPPKWL-G-PATWWLALPW-APKGSVSCSAWQMACRRVIK Botci1 --------------------------------MFEQ-KKLKREFMKVRHEMNATSSQDEFAKWAKLRRQHDKLFDQLEKSKSSLDSTVSTLRWLGTNGLRMLLFSKQAMFWLPKGWF-PYYAEWLLSFPR-APLGSISIQAWTLACAAVIL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ILLSIFLVLVAKQLVATIGKSTIQEFVWLVYLKVTY-NSKQHELHETNRQKRAISAQDEYAKWTKLNRQADKLSAELQKLNQEIQQQSNALILVLTTLPIWIAYRKTHLFYIRQGIF-PKYVEWVLALPF-LPNGAVGLTIWMFAVNSVVS Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------- Capow VFLFLFLFEFMRRRSAQIAAWVLDKVQ-------RETSELQRQVDELTEQQRPLSMQDDFAKYMKIDRQLIKLKKELQTRRAAASTALTSVVWWAALVFQGLLYRGTVIFSLPSSVY---PLERLMAYRSGGELGSISGVIWILVCRRVVS Catan2 PALTVLVGAIFIELVSWLGFTLISEQLFAVYRWVQQ-AQLRDEIFGLRKEVKGVSAMDEFAKWARVRRQLDGKTQAYEEITNTLRSTAQVFTRGLFYLVYLGLYRTTPMFYASDDWFGGGLIGWFLSLPF-APAGAISVVVWVYACRRVLR Cioin LFYTILMLSFARPMVPVVLRVLLPLIEMVV----MQKKELQIDLKQKLEDQRGINMMDEFAKYARLQRKIDAVKDEIQKMNNSTSNKLRLVIG--FSFL--YVHKHEAVLQYPKEWAGPDILAKIVAFPT-GEIGAVGGVFWLI------- CocheC53 LLLVVFILQLLLHVINTVGKNTVNELLWILYNKLRC-QILKKEIVQLKRELGNTSPQDNFSKWAKLDRQHNKAMAEYQKLDGSLRSHVSTLRWLGTQGLRFVLFAKSPMFWIPAGWV-PYYVEWILSFPR-APLGSVSINVWGIACASMIA Coere1 LALLVLVIEVLSAILDGIGYGTVAAALWDTYCRTER-LDLKSAIISLRRELHSVSSVDEFAKWAKMRRRLDSLSAKFERVSSDLAIEVNMVLRVVVYGVRAAVNYRVPVFFVPASWF-Y-PVLWFLSLPA-APMGSVSVTVWAFACNRV-- Conco1 LILSTSLICLFIEYIKFKGVWSSSHYVYPYYTWLRR-KKLNKKLLELKQEINSLDNKQEFSKWAKARRRHDKVQSEIDEIKKKQGYAFSVVAYIAMYLTMFLWFRSSPAFTLPYGWF-G-PLETYLSYPT-GQLGTLSILLWLVVCQKL-- Conpu1 LILTIFALVLFTEVVSWIGKSVLLELAWSLYRRIRQ-RQLKAELLTTKKELLQTSAQDQFAKWAKLRRSVDKGLAELEKLNNELSGSFNSLVWILTTGAQFVIYRRSAVFFLPPGWL-G-PLGWWMAFPF-APKGSVSVAVWQTACRRVIK Copci LLLTVFLIVFVTQLISWIGQNVLLEWAYNLYLRLRQ-RSLKTEILNNKTELLKTSAQDQFAKWAKLRRSVDKGLAELEKLNSEIATAFNAVIWALTSGVNLVIYGRKAVFYLPEGWM-G-PLTWWFSFPF-APRGSVSVGVWSFACKRVLL Croqu1 IAVYVFLVIFTGQLISWVGKTQLSEWAHALYLFLTQ-RNLRTTVLKTKSELQATSSQDEFAKWARLRRKMDKELQELDTLNKQIASDFSTLLWVFTSGLQFLLYRTNPVFFLPTGWF-PPTMVWLLGFPS-APYGAVSTTVWALVCKRALS CryneH991 LALVIFFCTLLNQIVSWVGKSVLQEIAFTAYSWVKQ-RKLRKQVLEDKAELGRTSSQDEFAKWAKLRRKLDKGLADLEKTNNTLSSSFSTLLWLMTTGAQFLLFRKQPIFWLPEGWV-PYPVAWLLSFPS-APIGSVSSGAWGAICRRVLS Crypa2 LLVIIFAVEVAVAVVNTIGAATINNLLWKLYISAGQ-RELQQSYLQVRHDLNATSSQDEFAKWAKLRRQHDKMLEELEKSKSGIDTTVNAVRWFCTSGARWFLYSRQPMFWLPHGWF-PHYAEWLISFPR-APMGSVSVVSWQLACTGVIT Debha1 LLISVLVVLFAKQLINAVGKATLENIGWSAYCKVAL-DQKNVELAKVSKERKSISAQDQYARWTKLNRQFDKLTGEINKLKEETSASIGYMILVTTTLPIWFFFRKAVLFYFPTGVL-PHYLEWFLALPF-ITTGGVGLTIWMSAVNNVVS Dekbr2 LFFLVSILTIFTNIIKSIGKDKIKNKIYSIYTRSKL-SQLRKERIQVNRQRNTISAQDNYAKWTKLNRKFDKLTEESKKEEVALAKKVDRVITFITVVPNNLVYSRVPLLYLPYGLLPAFLEIFVLNFPF-LPRGSIGVIIWSFCLNRTLN Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LALTIFLLVFVTELIQWIGQSVLLELAYAIHLRIQQ-RTLKNEILSAKAELLQTSSQDQFAKWAKLRRKVDKGLAELEKLNNDLGSAFNSFIWMLTTGAQFVIYRKAAVFFLPPGWF-G-PVTWFLSFPF-APAGSVSCGAWQMACRRVIK Fusgr1 LMLSVFVVEVIVNLVNTIGATAINNLLWTLINFLEQ-RKLQADYLKVRRDLNATSSQDEFARWAKLRRQHDKLLEQLEKTKKTTEASLTVVRIVVTRAPQYFLYATEPMFWLPHGWF-PYWAEWILSFPR-APIGSVSIASWQLACTGVIA Galma1 LLITIFLLVFIGQLVTWIGKTVLLDITYDTYLRIRQ-RALKTEILSTKAELLKTSAQDQFAKWAKLRRSVDKGLADLEKLNGEIAGSFNTLLWLLTTGLQFVVYRKQPVFYLPEGWL-G-PLGWWLALPF-APAGSVSVGVWQMACRRVIV Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 LALAIALVVLITEFILWFGYSQIASLAYGVYLNAKQ-RKTKRDILTIKHDLARTSSQDQFAKWAKLRRKLDSKMSELEKITTSLGYLFTTFLWVVTNGIQIVMYRSSPVFYLPQDWF-S-PISWIFSMPF-APSGSVSVPFWFLVCRKFVK Hisca1 LLITVLFLNVIIYVINTVGAATVDGLLWLLYIKLEQ-RHMKREVVQLKHEMSSTSSQDEFAKWAKLRRRHDKAMEAYEAKNNELTQSIKIARWAATSGLMLFLYSKTPIFTLPPGWI-PWQVQWVLSFPR-APMGTVSIQIWGGACATVVA Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LLITIFLLVFITQLVSWIGQTVLLELAYALYLRLRQ-QALKSEILATKSELLKTSAQDQFAKWAKLRRSVDKGLADLEKLNSQIASSFNSAIWILTTGVQFVVYRRQPVFYLPEGWF-G-PLAWWLAFPF-APAGSVSVGVWQMACKRVVV Lenti61 LMAMLFALVFVTELISWIGQSVLLEFVYSLYLRIKQ-RKLKSEILLNKKELLQTSAQDQFAKWAKLRRSVDKGLADLEKLNSELSTVFKSALWIMTTGLQFVIYRKAAVFFLPPGWF-G-PLTWWLAFPF-APAGSVSCGMWQMACKRVIK Malgl1 ---------------------ITNDEFRVFYVRIKL-SSMKKELFETRQLMNMTSAQDEFSKWAKLRRRVDKLSSQVDEQNKSLASSFKSFMFVLNSAIPFVLYKRVPMFYLPPGWF-G-PMGYLFSFPN-APAGAVSSTVWTTVCGRVLA Mellp23 LAVYVFLVVFSGQLISWIGSTQLSEWAHSIYLFLNQ-KSLRGTILKTKSEFQATSSQDEFAKWARLRRKMDKELQELDNLNKQIASDFSSVLWVFTSGLQFVLYRSSPVLLLPPGWF-PPTIVWLLSLPS-APYGAVSTTVWALVCKRALS Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LAFGVLLVVLLTELINLIGKTHFTALGYDIYLKVKQ-RALKKEVLTLKNELARTSSQDEFAKWAKLRRKMDSKIADLEKMTSELHVSFKGLLWFITSGLQFLMYRRSPVFYLPMRWF-G-PAEWVLSMPF-AERGSVSITIWFYFCRKFIT Mucci2 LPLTIFLLVLVTESILFLGYSYITSLTYDLYVKIKQ-QKMKRDTLKLKSELGQTSSQDEFAKWAKLRRKLDKSVADLEKMNADIAYSVKSVLWFLVHGSQLVMFRKSAVFYLPPGWF-G-PAQRILSWPF-APAGSVSVAIWFAACRRMIK Mydma LVIAVAVMVFLWEWISIVLK---PFIVWILNR--MQ-NDINVELLLLRKEQGTISIHNEFAKHARLQRKINLLTDKLDEIKRSQSSNSRILIGTFFSFLSAYLYYSVPVVILPSNWF--PYIGYIISYPC-NIEGAVSLPFWLLVCRQVSK Neucr2 LLVVIFVIELFVQLVNTIGAATINNLLWRIALSLAQ-RKKQKEYLAIRRELNATSSQDEFAKWARLRRQHDKLLEDLEKRKKELDAALTTVRVVATRGLQWFLYSREPMFWLPYGWF-PYYVEWFASFPR-APLGSVSIVVWQWACTGVIK Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 LVLTVFFVHVAIYLVNTIGASTIDSLLWLLYLKLKQ-QQLKRQVLEQKHEMNSTSSQDEFAKWAKARRRHDKSMEEYEALNKTLTAQVKIARWLSTNGLKIFLYSKTPVFPLPEAWF-PYYVEWIVSFPR-APLGSVSIHVWSNVCATTIA Phybl2 LPITIFLLVLGTELLLFIGYEYVASAAYDLYSQWKH-NKLKQDVLRMKAELSKTSSQDEFAKWAKMRRKLDKGVADQEKMSSEIAYSVKSAIWFFIHGSQLLMFYKRAVLYLPQGWF-G-PAQWILSFPF-APTGSISVAVWFAACRKTVK Picst3 LVVSLFTVLLIQQLVGFIGKSTIQEFAWLFYLRVAH-TKKQEELHKLNREKRSISAQDEYAKWTKLNRQAEKLTAEVKSLSDDIAKDVGVVLLFLTTLPLWVFFRKSVLFYLPTGVF-PYYVERVLAIPF-FASGSVGLTVWMFAVNNVIS Plicr1 LILTIFVIVFLTELVSWIGQSVLLELAYALYQRIRQ-RKLQAEILASKKELLQTSAQDQFARWAKLRRIVDKGLADLEK-----HTSFKGVLWMSTTGVQFIVYRGAAVFYLPPGWF-G-PLAWTLALPF-APKGAVSVGVWQMACRRVIR Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LGFYIFFLVASAQFIQWIGKTKLIDWTHYLYLWIDQ-AILKTQILKTKVEFQATSSQDQFAKWARLRRKIDKDLVDLEALNKEISSAFSSLLWTFTSGFQFVLYRRSPVFFLPQDWF-PSPIVWILSFPS-APYGAVSTTVWTIVCKRALA Punst1 LILTIFLLVFLTELVSWIGKSVLLELVYAVYLRIKQ-RKLKTEVLSTKAELMQTSAQDQFAKWAKLRRSVDKGLADLEKLNGELSSAFNSALWFFTTGLQFIVYRKAAVFYLPSEWL-G-PLAWWVALPF-APKGSVSCGMWQMACRRVIK Rhior3 -------------------------------------------MLKLKAEFSQTSSQDEFAKWAKLRRKLDKGMADLEKLSSDINYKFKSILFAFVYGSQTIMFRKSPVFYLPPGWF-G-PAQRFLSLPF-APA----------------- Rhoto1 LIAWLLLTTFVVELLGWVGTDTLAGYIYAPF---QQ-RAQKAEILKLRADLAATSSQDEFSKWARIRRKLDKAVQDLESSNADSSAHFKSALWVLTTVLPFIVHRRTPVFWLPKNWF-G-PLGWWLSFPS-APAGAVAVSVWTMACRRTLT Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LIETLFILIFITELIAVIGKTVLADLAFGLYARVKQ-RQLKKETLANKAAMLNTSAQDQFAKWAKLRRSVDKGLADIETTNKELAAAFNTAIWILTSGLLLVAYRSSPVFFLPKGWF-G-PFERPLSWPW-APTGSVSVYVYQMACRRVIK Schpo1 LIISTILLSLFIHFFDKFAKKRTIDGAYRIYVSVKN-KEILEQLLTVKKELNATSSQDQFAKWARLNRKYEQLSQEWEKQSANVKIFLSLFLWILTRGFRFYIESKTPVFFLPAFWA-----LWVLSLPR-SIYGSVSLTVWNFAVQKTIS Sorma LLVVIFAVELFVQLVNTIGAATINNLLWRIALSLAQ-RKKQKDYLAVRRELNATSSQDEFAKWARLRRQHDKLLEDLEKRKKDLDGSLTTVRVVATRGVQWFLYSREPMFWLPYGWF-PYYVEWFASFPR-APLGSVSIVVWQWACTGVLT Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 PLHLVILCAFFLQLFEWLGYGAIASKVWNWYDNIKI-NKLKREVIDVQTELGRTSAQDQFARWAKLRRRLDKLKADYETQAKQEASTISWGLRSFIWGAQFLLYRSTPMFYPPHDWL-G-PISPLLALPF-APMGSVSILCWFYACKSTFR Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 LILTIFALVFVSELISWIGKSVLLAFAWTIYQRIRQ-RELKTELLAKKQELQQTSAQDQFAKWARLRRTVDKGLQDLEKINSELSSSFNTALWVLTTGVQFIVYRSAAVFYLPPTWL-G-PLAWFLAFPF-APAGSVSCGVWQMVCRRVIK Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 VALIILGCVFVTQLVNWIGKSVLQDLTFALYSRIQQ-VNLRRQIISDKAQLNRTSSQDEFSKWAKLRRKVDKGLSDLEILNKSITSTFSSLLWISTTGIQIFIHRFQPIFWLPNGWI-PYPIEWILSFPS-APIGSVSSGAWCAICRRVLL Trire2 LMLIVFLVEATVSFINAVGAAKINDMLWTLINFLEQ-RKLQAEYLAVRREMNATSSQDEFAKWAKLRRKHDKLLEQLETTKKSLETALTALRLLITRAPQYIIYATEPMFWLPYGWF-PYYAEWIISFPR-APLGSVSIASWQLACTGIVT Umbra1 LATFILLLVIGTESILWLGYAYLTALTYDLYSKVRQ-RKLRKQVLQLRTELSQTSSQDQFAKWAKIRRKCDSATDSLEKTNSDIAIKVKGVLYFVVHGSQLLTFRKSPVFYLPHGWF-G-PVAWVLSLPF-APRGSVSVAVWFAACRRVCK Ustma22 PAIVIFLSVVVVQTIALMGKQRLQDILWLLYTAVQQ-RKLRREILTTKQQLSATSSQDQFAKWAKLRRSVDKQLGTLETINSTLASSVSGLVFIVTTVMPFVVYSKTAIFWLPPGWF-G-PAGWFLALPR-APKGAVSSTVWQMVCSRTLI Walse1 IAIQLLIAIVISEFIAIVPQDVVQSLVESIYNFTNQ-RQLRKDIMKTKKDLTSTSSQDEFSKWAKLKRRHDKLLKEHEDNKQTNTKAVKVVMFAIPSILQFGVNGKRTIIHLPPQWF-GSVLGLVFCLPF-SPRGTISATIYGMVVKRVLK Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3297.fasta_al_trimmed; alignment length = 97] Allma1 TLVVPTVS-TGNVPQLVADLLVDRVGDLGLL-NICGMPLEVYITVLQQRTPIVQ-GDWIKTVGFARVLVVASVVFTLEGDNLQDTLMTYQHLPLSWQ Ashgo11 TLVLPLVS-AGNVPQLCADVLLRFVRELDLH-PFVGTPLELFLYLVQQRSPVVQ-GPLLEELAPQRVVVLDSSIFIHEGDNNEDALLLCTELPISWK Aspfu1 ------------------------------------------------------------------------------------------------- Aurde31 ------------------------------------------------------------------------------------------------- Batde5 TLIMPGPNALGFVGQLTLDLLIQKVGSIDVS-AVVGTAMEVYVTVLMIRSKVEK-ESWIQSIGFSRVLLLTASWFTFEGDNMDTVHSIANAVPKSWD Botbo1 TLVLPIVS-TGNVAQLAVDLLIRRVGILDLF-SVTGTPLEIFFYVIQQRSPVLK-ADFVQQQKFGSLLVLSGLEFVLEGDNRADAQMLASVVPSSWR Botci1 ------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------- Canalb1 TLIIPSVS-IGNVPQLAIDLLIK-VDSLDLY-PFASHAAEVFLTLIQQRSPILP-YPFITSHEFDRILILDSVSYVYEGDNFYDGENLANKVPVSWA Cangl KLIIPLIG-TGNVPQLSIDLLLNYVKRIDCY-PFSGSAIELFIYVIQQRTPIIP-GPVLHEYQITELIVLDSSTFVHEGDNSEDAYTFYNNLPVSWK Capow TLILPCES-VGNVGQLCIDLLGQRIGFLHLL-PAAGTAAEVFIVLIQQRAPIVK-SQWFTQHEFAKILVLASFKFCAEGDNRADAARLASLVPASWH Catan2 VLIVPTVS-TGNVPQLLGDLVVARIGSLAVL-NVVGMPIEVYLTLLQLRSPVIQ-GAWAQSVGFKQVLVLASLTFAMEGDNLQDTMMAFAKVPVSWA Cioin ------------------------------------------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------------------------- Coere1 TLVLPSVS-IGNVPQLAVDLLISRIGILDLI-PISGVPVEVYWTIIQQRSPPLP-KDFIKQGEFSKVVLLTSVALANEGDNVPDAINLANATPKSWE Conco1 ------------------------------------------------------------------------------------------------- Conpu1 ------------------------------------------------------------------------------------------------- Copci TLVVPIVS-TANVGQLAADLLIERIAILDSI-PVVGTPLELFLVVLQQRSPILV-SDFIQISQFSAVLFLSGLQFVIEGDNRADATLLATVVPSSWA Croqu1 TLILPIVS-LGNVPQLAVDLLISRIGWIDHI-PVVGCPVEVYVTILQQRSPVLK-SQWISEAGFNSILVLVSLMYVAEGDSRPDAKALAHAVPDSWK CryneH991 TLILPVVS-LGNVPQLTADLLIKRVGFVGTVTPFAGGGLEVYLYVIQQRSPTLK-SNFVNSNAFGAVLVLTSAAWCVEGDNRGDARSLAGVVPVSWE Crypa2 ------------------------------------------------------------------------------------------------- Debha1 TLIIPSIS-IGNIPQLANDLLIK-IGSLTLY-PFASTAVEVYLTIIQQRSPIIP-SPFIKEAKVKRFLILDSVSYVYEGDNFYDGEHLANKTPRSWL Dekbr2 TLILPIVS-IGNVPQLTVDLLIKLVGRLDIY-PFSATGLEVYLTIIQQRSPIIS-GPFVELCEFKNVVVLQSSTFVYEGDNSKDAEQLYDCAPKSWK Dicdi TLIWPSLT-LGNIGQLTIDVLIKRIGFIVIT-PIIGTSIEVYITLVQQRSPIVD-GKWINAEEIKEILFLSSNLFCSEGYNTNEALQMSNLIPSCWK Dmel TVIIPSIC-VGNAAQLACDLLIRRIGSITLI-PVYGSSCELYLLVVQFRAPWVA-RELLKGAR--RVVILSGFRYLLEGDNSTDASLIVRELPKSWN Enthi ILFIPCWS-VGNVGQLCADLIIKQQVILQLI-PYVAFAATIYMNVIQLRSTFIA-SECIKSLQPSEVIFLYSHCTCYEGDNRPDAIQMYSLLVQSWN Falba PLFHPDKS--------------TRPGT-----PFAGTLVLTFCTILQQRSPAVE-GDWILRAGFSDVWLLTGARFTADGDNKSDAYIVATAVPFSWR Fomme1 TLIVPVVS-VGNVSQLAADLLIEQIGVFDLV-PVIGTPLELYILVIQQRSPVLK-SAFIQENNIGAVLYLTGLQFVLEGDNRADAEFFAGVVPPSWS Fusgr1 ------------------------------------------------------------------------------------------------- Galma1 VIVVPVVS-TANVGQLSVDLLIERVAIFDCV-PVVGTPLELYFVVIQQRSPILK-SSFIKEYRFSAALFLSGLQFVLEGDNRADAGLLASVIPGSWR Ganpr1 TLVLPSPNSIANLGQLSADLVTPLVGWLGLLLPLVGGETELYLTVLQIRSAVIK-GSWIRHSQFSRVIVLGSVGFAVEGDNLSDAMLLSSVAPASWS Gloin1 ------------------------------------------------------------------------------------------------- Hisca1 ------------------------------------------------------------------------------------------------- Klula1 TLLLPLVS-TGNVSQLCVDLVLTFVKELDLH-SFIGTPLELFLYVIQQRSPVIA-GPLIKSYGIESVIVLDSSKVVHEGDNSWDAFQICEKLPVSWK Lacbi2 TLIVPVVS-TANVSQLATDLLIDRIAIFDCV-PVAGVPLELYVVIVQQRSPVLK-SKFIDSSNFETVLFLSGLQFVLEGDNRGDARLLAAVTPKSWQ Lenti61 ------------------------------------------------------------------------------------------------- Malgl1 ---------------------------MSVY-----TPLDVYITIVQQRSPVLK-VEWIKRAGFTDVLLVSSFMFCAEGDNRMDAHVYAEQIPP--- Mellp23 ILILPIVS-LGNVPQLAIDLLIKRIGNLDHI-PILARPFEVYITILQQRSPVLK-SKWIKSQNFSSVLLLISLIYVAEGDGRLDAKVLALEVRSDAR Mnele ------------------------------------------------------------------------------------------------- Monbr TIVVPAFC-VGNVSQLCADVLVMPALALDLV-PAIG------------------------------------IMTAAEG---------------AWP Morel2 TLILPSVS-IGNVPQLTTDLLLDRVGCIEVV-PVLGLAVEVFWTLIQQRSPTVS-HRFIQDSEFDQVVLLASVAFAMEGDNAPDAIFLANVLPKSWD Mucci2 TLILPTVS-IGNVPQLASDLIIERVGFLDVM-PVSGVPIEVYWTCIQQRSPTIK-GRFAA--QFQQVVLLTSLMFALEGDNVQDGIEFARFIPKSWK Mydma TIIMTSVS-FGNVSQLTTDLLLVLLGFIIVL-PVTGASLEVFLIIVQQRAPFIK-GSWIDKSCFSKVVMYAGLVYCIPGYEFDDVILLLSRLPPSWN Neucr2 ------------------------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------------------- Phybl2 TLVLPTVS-IGNVPQLTCDLIIDRVGFLDVL-PVAGVPIEVFWTVVQQRAPTEK-GEFVKVHKFSQVVLLTSSMFALEGDNVSDSIAFVNFVPKSWE Picst3 TLVIPAIS-IGNIPQFTVDLLIK-IGTLDLY-PFASNAIEVYKTVIQQRSPIIP-SPFVVKSGFDKVVILDSVTYVYEGDNFADSEILANKLPISWY Plicr1 VLVVPVVS-TANVSQLAADLLIHRIGIFDLV-PVVGTPLELHVLVIQQRSPALK-SGFIKESGISSVLFLSGLQFVLEGDNRADANLLAAVAPSSWQ Polpo ILIWPALT-LGNVGQLSIDLILKKVGYIHIV-PLAGTAVEVYITIVQQRSPIIA-GQWIKQSGFSQLLFLAS-LFCSEGDNTQDAIVMSNHVPSSWS Pucgr2 ------------------------------------------------------------------------VAYVAEGDNRLDAKAFACEV----- Punst1 TLIVPVVT-VANLPQLAADLLIKRIGLFDVI-PVVGLPLELYVVILQQRSPALK-SEFIRSSNFRAVLFMCGVQFVLEGDNRFDAGLMATAAPTSWR Rhior3 TLILPMVS-IGNIPQLTADLFIDRVGFLDVI-PVSSVPIEVYWTCIQQRSPTIK-GQFAS--QFDRVVLLTSIMFALEGDNVQDSIEFGNYIPKSWE Rhoto1 TLLLPQPS-LSSLAQLACDLLVELVGYLGHV-PAVGLGVEVYLTVVLPRSPVIR-AQWITKCGFKEVLVVAGLIYTSEGDASSAAHLLADALPRSWE Rozal11 ------------------------------------------------------------------------------------------------- Sacce1 CLVLPLVS-VGNIPQLSIDWLLEYLEALDLV-EFVGSALEVFLFAIQQRTPLVSVNPFLSKYNISEICIWDSSCLANEGDNSLDSQQFLQWIPISWQ Salro TLVVPSVS-IGNTAQLAVDLLT-------AVLPFAGTEMQVHLVVLQIRSAIAR-QKWIQSKSFGRTLLLTSSIFTGPGDNTMQAHMLG---PSSWK Schco3 ILILPIVS-TANVSQLAVDLLIRKLSILDLV-PVAGTPIELYFVVIQQRSPVLK-TEFARLSRPSALITLSGLHFVLEGDNRSDAHLLAAVVPPSWS Schpo1 ------------------------------------------------------------------------------------------------- Sorma ------------------------------------------------------------------------------------------------- Sphar TLVLPAVS-IGNVPQLTVDLLIKRVGFLHLL-PVFGTSADVYLAIIQQRSPAIK-SEWITAANFGSVVLLTSV-------------------GAQWD Spipu1 TLLMPGPNGLGNIGQLALDLLIMRVGFISVL-PVCGTSFEVYITLIQLRSPVIT-KHWAQQMAFESVVLVTAIWFAIEGDNYQDALQLASAVPLSWK Sporo1 TLLLPQPS-LASVAQLSVDLIVVRIGFLGHV-PAVSYSVEVFLTVVLPRSPVIR-ARFIQLGQFKEVLIVAGLIYTFESTEPSTAFYLADALPKSWE Stehi1 ILVVPIVS-IGNISQLASSLLIECIGRFDLV-PAVGTPLELYGFNVVDR-------AFITDSQFSAILFLSGLQFVTEGDNRSDAFLMATAIPLSWQ Tapde11 ------------------------------------------------------------------------------------------------- Thetr TVFMPSLS-IGNVGQLTADILVRLVGSLDVV-PVVGSALDVYVAVIQQRAPLIK-GGWLSKAQATALVWLHSQAFAAEGDNIRDALNMASLLPPSWA Treme1 LLVVPSVS-LANLPQLTADLLIKRVGWIGTVIPFAGGGMEVYIYVVQQRSPTLK-IDFLSSVNPSFVLILTSAAWCAEGDNRGDAVEFTRTVPLSWA Trire2 ------------------------------------------------------------------------------------------------- Umbra1 TLIIPTVS-IANVPQLTVDLYVERVGFLEVM-PVAGVALEVYFTFVQQRTPIFK-GAFIVASGFAKTLIMTSIMFALEGDNLQDTIQYANCLPASWQ Ustma22 TLIIPAVS-IGSVPQLAVDLLLVKVGRIDCF-PFVGTSLEVFVTVIQQRSPVYK-SDWITTSHFKEVLWLTSLYFAAEGDTRPDAHNLATLVPRSWS Walse1 TLVLPTIS-MANVPQLATELLL--VGRFNFI-QVAGTPLELHIYVVDQRSPILK-SKWADGLNLS-VIILSSCLFTTEGDNRPDAHLLVKALPLHWE Zygro1 TLLIPLVS-TGNVPQLTTDLVLQFVKCLDLH-PFVGTALELFLYVIQQRTPVIQ-GPLVQEFKITDVVILDSSAFVHEGDNSYDAHLLCDHLPISWK [Cluster3301.fasta_al_trimmed; alignment length = 51] Allma1 ILGIGVDLLDTRRLVQLAFLRRVLRWAAKEATYKACLSVSHDGDHLVAMVV Ashgo11 VLGIGTDLVYMPRVVELLFAGKFMVWAAKEALYKAVLSVSHDEDYLVAFVC Aspfu1 PLNIGTDVVHLPRILRLIFTRRILRFAAKEAARKAALSISHDGDYVVATVL Aurde31 LLGVGVDVLHVPRLRALLFARRILAWALKEAAYKAFCSVSHDGDYVFATVI Batde5 -------------MAGMLSTHKAIRFAIKEAAFKAMVSVTHDADIIAAVAV Botbo1 ILGVGIDILHLPRLRSLLLAKRILRWTAKEAAYKALVSVSHDGEYVAANVL Botci1 LIG-----LVAPKEAPLLDSKKLTRFAAKEAAKKAFMSISHDGDYATAVCM Caeel --------------------------------------------------- Canalb1 VLGIGVDIVNSVRFERLLLSKRILSWAAKEALFKTLLSISHDDSLVIATVL Cangl VLGVGCDVVHLPRMHRLLVVSKFMTWALKEAALKALSTLSHDNEYLVAYTT Capow VVAIGTDLVAVSRIAAVYSSSKVLRWALKEATYKACISLSHDGDYALAFVV Catan2 ILGIGVDILDTSRIARLLFARRIL--AAKEAVFKACLSVSHDGEYLVAMVV Cioin --------------------------------------------------- CocheC53 PFRVGTDICSISRLRSVIFLKRVLRFAAKEACRKACISISHDGDFATAVAI Coere1 IMGVGVDILYAARIEAIVFARRILRWCLKEAIYKAAISFSHDQGMMIGYAI Conco1 IIGIGTDILKKSRIKNLLFPKKILRWSCKESLYKALLSVSHDGDFVVSYVI Conpu1 IHGIGIDIVHVSRIASLVLARRILRWAVKEAAYKALVSVSHDGEYVVASVV Copci ILGIGVDIIHTPRISALLFVKKILRWSVKEAAYKALVSFYE---------- Croqu1 IFGVGIDILDIRRLHR--FIKRILRWTAKEAAFKALVSISHDGNYVVAIVV CryneH991 LSGLGIDILSLSRFRDFVVAKRICRWCIKEAAYKSLSSLSHDAGVVVGVVI Crypa2 NLNIGTDLCHVVRIRQILFIERILRFAAKEAVIKAHISISHDGDYATAVCL Debha1 TLGIGVDIIKTNRFKELLISSRILSWASKEAVYKTLLSVSHDDGLLVATVL Dekbr2 VISIGTDIHLLGRFKNILLCQKILAWCVKEAIYKCLCTVSHDGSYIISTVL Dicdi IFGIGNDIVKISRLESSFFLKRAFRWAAKESIYKAILAISHDTDYAISNVI Dmel --------------------------------------------------- Enthi --------------------------------------------------- Falba IVGIGVDIVPLARVKGMVLSRRLLCFAAKEATYKAAVSLSHDGGMVVAMVV Fomme1 ILGVGIDIVHLPRIASLVLAQRILRFSVKEAAYKALVSVSHDGEYVVSTVI Fusgr1 --------------------------------------------------- Galma1 ILGIGVDLVHVPRIAALLFAARILRWCVKEAAYKAMVSVSHDGEYVYSSVL Ganpr1 IVGVGIDIVNIPRIQRILFLRRILRWAFKEAAYKALCSVSHDGEYLVGQVI Gloin1 --------------------------------------------------- Hisca1 PLSIGTDIVHLPRICRLIFIRRILRFAAKEAARKAALSISHDGDYVVATVL Klula1 VISAATDIVFLPRVEKLLILKKFMVWASKESLFKTLISISHDQDYLICILL Lacbi2 ILGIGVDLVNIPRITALLFASRILRWGVKEAAYKAMVSVSHDGDYVYASVL Lenti61 ILGIGVDVLHVPRILRLLFAQRILRWSIKEAAYKAVASVSHDGDYVYTTVL Malgl1 --------------------------------------------------- Mellp23 ------------------------RWAAKEAAFKALMSLSHDGDYVVAIVV Mnele --------------------------------------------------- Monbr --------------------------------------------------- Morel2 ILGIGIDILHLPRLKLALFLTRILRWALKEATYKAMCSVSHDGEYLVAQVL Mucci2 IIGVGVDIVHLPRIAALILARRIL-----EAVYKALVSLSHDGEYAIAQVI Mydma --------------------------------------------------- Neucr2 --------------------------------------------------- Orpsp11 --------------------------------------------------- Pench1 PLNIGTDIVHIPRIARLLFTRRILRFAAKEAARKAALSISHDGEYVVATVL Phybl2 ILGIGVDLLHLPRLASLVLAKRILIWCIKEAIYKALVSLSHDGDYVIAQIL Picst3 VLGIGVDVVNTDRFRRLVLTARILSWASKEAVFKTLLSISHDSNVLVASAL Plicr1 ILGHGVDLVHLPRISSILLAKRILRWGVKEAAYKALVSVSHDGDYVLASVI Polpo ILGIGNDIVKISRF--TVFLKRAFRWAAKESVYKAFISISHDTDYAIANKS Pucgr2 ILGLGIDILDRSRLARLLLAERILRWTAKEAAYKALVSIAHDGPFTVASVI Punst1 --------------------------------------------------- Rhior3 --------------------------------------------------- Rhoto1 ILGIGVDVLHLPRLRSLLLARRILRWTAKEAAYKALLSVSHDADLMVAYVV Rozal11 LLGIGTDLLCLRRFFDICVARKILRFSVKEAAYKAMASVSHDADMLSSFVV Sacce1 IAGVGVDIVYLPRFAHILITRKFMVWALKECSLKALVSLSHDKDYLIAVTN Salro --------------------------------------------------- Schco3 ILGIGVDLVHVPHIAAALFPGRILRWAVKEAAYKALTSVSHDGEYVIANVL Schpo1 -MGLGIDILKISRISRLIFLKKCLRWCVKEAVFKALVSVSHEEDLVVANAL Sorma --------------------------------------------------- Sphar IKGLGVDLVQVSRIRNAIFLEKVYRWAVKEAVYKAVLSISHDGDYAMAQVI Spipu1 IIGIGVDTCHLPHLHSLLLVRRIFRWAAKEAAFKALVSLSHDGEIAMAYVV Sporo1 --------------------------------------------------- Stehi1 IIGIGVDILHLPRLVSLTFLAPCHRWAIKEAAYKAVASVSHDGEYIFATVL Tapde11 --------------------------------------------------- Thetr VLGLGTDIVSVARVAATVFVQRVLQWAAKEAVYKALISLSHEESHAVATAI Treme1 IIGVGIDILSIDRLRGVILARRICRWTAKEAAYKALLSLSGDAGVVVGVVV Trire2 PLNIGTDICRISRIYAILFVKRIFRFAAKEAAIKAHISISHDGDYATAVCM Umbra1 LLGIGVDIVHLPRIAKILLCRRILCWSIKEAMYKAMISVSHDGDYAVAYAV Ustma22 --------------------------------------------------- Walse1 --------------------------------------------------- Zygro1 VLGIGTDIVFTPRISHLLLTTKFMVWATKECVWKAMLSISHDKDYLVAFMT [Cluster3303.fasta_al_trimmed; alignment length = 34] Allma1 ---------------------------------- Ashgo11 ---------------------------------- Aspfu1 KTVGFT-RFRSTKNTKVPGNTVYRQYMNRVGGFN Aurde31 AMMGFA-GFDTTKGKPVEGNRTWRQYMNRRGGFN Batde5 LLMGID-GFDSTKGKKVPGTRQYRQYMNRSKGFN Botbo1 ---------------------------------- Botci1 AMMGFG-GFATTQNKQVAGNTQYRQYMNRVGGFN Caeel AAMGFG-GFDTTKNKQVNDNRRYRQYMNRKGGFN Canalb1 ---------------------------------- Cangl ---------------------------------- Capow RMMGIS-GFGSTKGKHVPGARRYRQYMNRRGGFN Catan2 ---------------------------------- Cioin ---------------------------------- CocheC53 KVMGFG-GFKSTKNTKVPGNLQARQYMNRQGGFN Coere1 ALMGFN-GFNTTKDKTVAGNRKFRQYMNRKGGFN Conco1 AMMGFS-GFGTTKGQHVAGARQYRQYMNRRSGLN Conpu1 VAMGMS-GFGSTKGKHVEGNRTWRQYMNRRGGFN Copci AMMGIA-GFGTTKGKQVLGNRTWRQYMNRRGGFN Croqu1 RLMGFS-SLTTTKGKRVAGNRTWRQYMNRRGGFN CryneH991 AMMGFG-GFNSTKKKGIGQNRTWRQYMNRRGGFN Crypa2 AMMGFG-GFGSTKGKKVVGNTEYRQYMNRVGGFN Debha1 SLMGFG-GFGTTKGKHVKGTSEYRTYMNRSKGFN Dekbr2 KMMGFS-GFGSTKNKKVEGTNEYRQYINRKKGFN Dicdi RQMGVPVNFSSTKGKKVEGNREYRQFMNKR---- Dmel ---------------------------------- Enthi KKMGLVNGFCSTKGKHVKGNKIFNLLINKRGVHQ Falba AFLGFS-GFSSTQGKQVAG-RTYRQYMNRVGGFN Fomme1 VLMGFG-GFDSTKGKPVTGNRTWRQYMNRRGGFN Fusgr1 AMMGFG-GFGTTKNKKVLGNTEYRQYMNRNGGFN Galma1 AMMGVG-GFGSTKGKHVSGNRTWRQYMNRRGGFN Ganpr1 ---------------------------------- Gloin1 KAMGIA-GFNTTKGKKVVGNRQYRQYMNRRGGFN Hisca1 KTMGFS-SFRTTQNTKVPGNTQYRQYMNRQGGFN Klula1 ---------------------------------- Lacbi2 AMMGLN-GFGSTKGKPVAGNRTWRQYMNRRGGFN Lenti61 AMMGLT-GFGTTKGKHVEGNRTWRQYMNRRGGFN Malgl1 ---------------------------------- Mellp23 RLMGFS-SLSTTKGKHVNGNRTWRQYMNRRGGFN Mnele KLMGFS-SFDSTKGKHTDGSRKYRQYMNRRGGFN Monbr SAMGIA-GFGTTQGQHVKGNRRFRQYMNRKGGFN Morel2 AMMGFG-GFDSTKGKKVAGARKHRQYMNRRGGFN Mucci2 ---------------------------------- Mydma QLMGFT-GFVTTKNKHVEGNRKFRQYMNRRGGFN Neucr2 ---------------------------------- Orpsp11 ---------------------------------- Pench1 KAMGFS-RFRSTKNTKIPGNIEYRQYMNRQGGFN Phybl2 KLMGFG-GFDTTKNKHVAGTIKYRQYMNRRGGFN Picst3 SLMGFS-GFGSTKGKHVKAATEYRQYMNRSKGFN Plicr1 AIMGLQ-GFGTTKNKQVEGNRTWRQYMNRRGGFN Polpo RQMGIPVTFGSTKGKKVDGNRQYKQFMNKRVVKN Pucgr2 RLMGFS-SLTTTKGKHVAGNRTWRQYMNRRGGFN Punst1 -AMGLT-GFGTTKGKHVEGNRTWRQYMNRRGGFN Rhior3 KLMGFG-GFDTTKNKKVPGAIKYRQYMNRRGGFN Rhoto1 ALMGFG-GFGTTQGK-AHEDRHYRQYMNRKGGFN Rozal11 KMLGFN-GFNSTK---VTGNRKYRKYMGKKNDFT Sacce1 ---------------------------------- Salro SMLGFG-GFGTTKGQHVDGNRKFRQYMNRKGGFN Schco3 QMMGLS-GFGSTKNKHVEGNRTWRQYMNRRGGFN Schpo1 RIMGFS-GFDTTTGKK--HGTKYRQYMNRPGGFN Sorma ---------------------------------- Sphar KLMGFS-SFDSTQGQHVPGTREYRQYMNRRGGFN Spipu1 ALMGIT-GFDSTHGKKVAGTRTYRQYMNRRRGFN Sporo1 ---------------------------------- Stehi1 AMMGMS-GFGTTKGKHVQGNRTWRQYMNRYGILA Tapde11 AMLGFG-GFSTTKGEKVKGNIEYRQYMNRPGGFN Thetr ---------------------------------- Treme1 AMMGFG-GFGTTKGKGFGVNRTWRQYMNRRGGFN Trire2 ALMGFG-GFDTTKGKKIPGNSEYRQYMNRQGGFN Umbra1 KLMGFG-GFDSTKGKHVAGAPKYRQYMNRRGGFN Ustma22 AMMGFG-GFGTTKNKKVAGNRTWRQYMNRKGGFN Walse1 QMMGFG-GFDTTKGKKVVGNRTYRQYMNRVGGFN Zygro1 ---------------------------------- [Cluster3310.fasta_al_trimmed; alignment length = 133] Allma1 ------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 -----TGISVSRVLARG-ASTA--P-YKDTFAVFATATTAALLLI-FNYEKVQSPVVTNTMYQMRLGVVRELLG--DNLEFGGWVHGELNQVAGRVNVRFTLKGSKGVPGEVRLVADRENRIREWTVTID-GK Aspfu1 RRIGVAFLFR-RHNMPP-IPAPKAS-INTTLPIFVVVVGAAMLGI-FNYQKSSSSVVSSTLYALRSPRAREILG--DEIYFAPWISGEMNQLHGRIDISFWVKGTKGQ-GKMRFRSIRPDRTEEWSLETE-DG Aurde31 -------------------MSPAPE-LKRTLLAAGVVGWGIFAMRATNAERATSSVMRQLVFDLRSEEAAAILG--DDLKPEPRVQGTMSILQGKVDISFRLQGSKGA-GTVYFTSIRKARILRFRVVCD-DG Batde5 ------------------------V----GLGAAGLSFWAYTIINATNSNKSHNSIFKGVMFHLRDPRALALLG--DDIFYDKPVQGTFNVIRGVADYSFTLQGSQAV-GNVRFKGHHIPASVIFELDC--NG Botbo1 ----MRPAASSRQISLVLTTGPRPR-VKSTIGVLGVSAWAGFVLYATNQERLSSSVMRQILHKLRNSAIAEVLG--VGIAPEPWISGAINLLQGNVDLSFRVKGSKGS-GTVYFTSIREAKILRFKIICD-DG Botci1 ------------------------------------------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------------------------------------------- Canalb1 KNVNLSNLFRSIMISRQ-TSSIILP-FSKYLLIYGIGITLSCIAI-FNYEKTQSPIITSSLYFLRSQPSIELLG--KDIDYSPWIWGKLNTVQGIINIEFSVKGSKG-NGVVKLNATRESKVHQFVLEVE-RD Cangl R--MLTALAA----VRG-------P-MAGAFAAFSLATGSALAVI-FNYEKTESAIVSNTMYYMRSGQTIDALG--ENIEFAPWVWGELNPVAGKINITFSVKGKKGVTGIVKLVADRENRIHEWSLTVP-DK Capow ------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ARPQAQCLRRASTTPPQQIPPPKDP-VPPTLPIFIIAMTVSLFAF-FNYQKQESSVVTATLYALRNPLVREQLG--DEIYFAPWIKGEINQVHGRIDVSFWVKGTKQA-GEVRLKCRRKGRTQEYSLTLE-DG Coere1 PQFSRTSLVQAAASTPTTSATPSQ--VPKIFVAVAAVTWGLGTVIAFNYQRMTSTPVTAALFTARNEGVCKAFG--KHLNFAPWISGDISHLKGFVDVEFDVIGDKDVVGHLVLKSRRVGKTVEFYVTTP-DG Conco1 KR---LPLN--SIVNRSTLSTQFPE-IPNAYAILGVLGWVGALGVLTNYQKQNTSITNSTLFICKEPNSVEALG--EDIDFQPWISGYINHLKGKIDISYWVKGSKGT-GKLHFRAIRKV-PLEFTVTLK-DG Conpu1 TRNAVRPQARSSASRRAQTRSRHPR-LKNALSVVGVSAWAAFFYIAANQERVASSITQQLLATVRSPEVGALLG--DVVRPEPWVSGAINLPAGNVDLSFRIKGHKGA-GTVYFTSIRKAKPLRFRLITD-DG Copci -MASLQPCRL-----TVLTNAQRPR-IKSATLAVAACGGALFMTYATNQEKLSSSVFRSIIRSLRDPQMHEALG--DAIRPQPRVIGRISVLQGNIDVSFRVKGSKGS-GTVYFTSIRKEKVLRFKVICD-DG Croqu1 ERNKVNL--RLRPTSTSSAKNPTKE-LPNLTFVAISGVWATFVYFSTNAEKANSTVVNAVLFELRNPVSQEALG--SPIRAE-WVDGQINLMQGAVDVAFRVKGSSNS-GKVYFTSVRRERIIRWKLIRD-DG CryneH991 PRPAAALRRLTRPPPPPPKASPRQK-VRGALGLLGLGWGL-FILHATNSERLSSSVLRQATFQLRSKEVIALLG--ENVRLVPWISGTINLMQGRVDLSFRIRGSKGA-GTVYFTSIRPQEIGKYSF-----S Crypa2 RRPL-QALRSGRSLL---IAAPKPD-VEATMPIFLALVAASSIAI-FNYQKMSSPVVSSTLYALRNAQAREYLG--DEIYFKPWISGEMNQMHGRINISFSVKGTKNT-GVMRFASFRPTSTTEWSLETT-DG Debha1 RNIGISTLTKRINVTRG-TSS---P-FKAYFLAYGLGVTLACAVI-FNYEKTTSPIINSVMYFLRSQNAKQLLG--EDIGFKPWIWGTLNTVRGDIDIEFAVQGSQN-TGKLKLKATRESKIHHWILQIN-DA Dekbr2 ----------KEYIPEG-------PHIKEAFSIFALFILVATASV-FQYEKVSTPVMNATMYYLRSQLARSHLG--NEITYSPYISGEVNTVKGVVNIHTKVEGKKG-KAVMYLKAGRASTIDVWKLVQD-DG Dicdi ------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------SFLSSVGVAAGLGVWAVVLSAAVNYGKTCSPLVVDILFNLRAPVLHHYLG--EPITTG-WINGPINHYKGVADINFRVSGPKDN-GRIFVNARRR--LSEVKLVLDSDP Fomme1 ------------------------I-VSSAFGIVGVAGWGAFLAYSTNQERLSSSVVRQILLNLRSPLVREALG--EGVRPEPWINGSINMLQGNVDISMRVKGSKGA-GTLYFTSIRREKILRFKIICD-NK Fusgr1 PRLV---QRRTR----TVTPAPKPD-ISDTFPIFLLIVAASSVAI-FNYQKMSSPVVSSTLYALRNSEARALLG--DEIYFRPWIHGEMNQLHGRIDIWFSVRGTKGE-GVMRFASNRPTSTTEWSLTME-DG Galma1 --MSINVAKLRAVATASTTELPRPK-ARSAALVAGVSGWAAFMTFATNHEKLSSSVFRSIIRALRDPQLHEALG--EAIRPQPHVKGHISQLQGNIDVSFRVRGSKGS-GTLYFTSIRKEKVLRFRVICD-DG Ganpr1 ------------------------R-LGKNVGLALGTVWGGSLYWYYMFEKRTTPIFKLVMFRLRDPRAEKMLG--NNIEL-GHVSGTVTETKGIIDCTFWVQGSHGS-AAVEVKGRRDSEIEKFIVKNE-SG Gloin1 -----------------------------------------AIIASFNYQRLNSSTVQGSLFNLKHPKALELLG--KNINFTPWIKGSINHLKGKVDFQYTVKGDKGK-GSVHFRSIRDLHITEFTLTTE-DG Hisca1 -----PKLATHRATFHPATSASRLS-IK-TLPIFFVVVGASMLGI-FNYQKSSSSIVNSTLYALRSPKGRELLG--DEIYFAPWISGEMNQLHGRIDISFWVKGTKGK-AKMRFQSTRDGRTNNWSLTLE-DG Klula1 -----SGISVSRILTRR-ASQE--P-TKDQFVGFIVLMTSALAMI-FNYEKTQSPVISNTLYHMRSPKIREVLG--DQIDFDPWVSGELNQVAGNVNIKFYLKGSKGKVGEVRLVADRENQIHEWSVKVD-DK Lacbi2 -MASIAVRQRREALGSCITELPRPK-IKSSALTIAVLGWSGFMAYVTNQEKLSSSVSRSILRAVRDPQLRQVLG--EVIRPQPWISGHINQLQGNIDVSFRIRGSRSS-GTIYFTSIRKEKVLRFKVICD-DG Lenti61 ---MPAPLRVFRPLTTTYTHQYKPP-LQNALGALGVSAWGLFMVFVTNQEKLSSSIMQQIMNTVTNPELREVLG--EAIRPEPWIDGAIHIPGGNIDLSFRVKGHKGA-GTLYFTSIRRVKILRFKVIAD-DG Malgl1 ----------SRPVQPGH------P-LPNAGGASLVALWYVLSAYFNNKERVGSSVLRMVSQRVRAPEVYELLG--EPVRIKPWIEGIINPLKGKVDMSFEVVGPRGV-GTVYFTSVRKHKLLRFLVVPHGDT Mellp23 RKASWQLSERHRSTSTSSVKNPTKA-LPDLTFLAISGVWVTFVYFSTNAEKANSSVVKAVLFELRNPMSKEALG--TSIRPE-WVDGQINLMQGAVDVAFRVTGSSDS-GKVYFTSVRRERIS---------- Mnele ------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------- Morel2 QR---LGLQRPRVSSKPSASKQTTN-VASLAGIFGVVFWAGSIAVAANHQRQGTSIVRGTLFNVKDTKAQELLG--NNIDFVPWISGTVAHLKGRVDIEFQVRGDKAE-GRVHFVAVRPA-TTDFTLTMP-DG Mucci2 SRLASRPLA--RTLLSSC---SFAP-PPPTGIGVGAVVWAVGLGAALNHQRLSSSVVHGTLFMVRDPRVIALVG--DHVDYAPWISGTVNHLKGKIDIGFDVKGSTGEVARVHFISKRGG-TVEFTVVRKSDN Mydma ------------------------------------------------------------------------------------------------------------------------------------- Neucr2 RMAL-RALARGRAQP---TSAPRPD-VQTTFPIFLGIVAATSIAI-FNYQKLSSPVVESTLYALRNQRAREYLG--DEIYFKPWISGEMNQLHGRIDIKFNVKGTKRT-GVMRFASFRPTPTTEWSLETE-DG Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------- Pench1 TR---AALARARPNIAS-IAAPGPN-PN-TLPIFIIATGAGMLGI-FNYQKSSSSIVNSTLYALRSPRAREILG--DEIYFAPWISGEMNQLHGRIDISFWVKGTKSQ-GKMKFRSIRPDRTEEWSLETE-DG Phybl2 IRAITRPLT--SRIASQTESTTRVP-APKGGALVGAAVWAGVLGYAMNYQRLSSSIVNGTLFMVRDPRIIELVG--DQVDYAPWISGSVNHLKGKVDIGFDVTGKSGERARVHFESVRSG-TIEFTVTRLSDK Picst3 ------------------------P-FANYFVSYAIGITLACAII-FNYEKTRSPITNSTLYFLRSALAKEHLG--EGIDFRPWISGPLNTVKGDIDISFVVQGSKS-KGVLKLKASRDTKVHHFILEVT-DS Plicr1 -MASISARARSQPARTRTTELPRPQ-INNLALVTGVTGWAAFLLLATNQEKVASSVVRQIVRTIRDPTLYEVLG--DAIRPEPWISGKVNQLQGNIDVSFRVKGHRGA-GTVYFTSIRRAKILRFKVIAD-DG Polpo ------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RLANRRTA-RHRLINTSSVKNPTQE-LPSGSFLVIASVWAGFIYFSTNAEKANSSIVKAVLFELRNPSVLAALG--QSIKPE-WVDGQINLMQGSVDVAFRVTGSERS-GKVYFTSVRRERIIRWKLIRD-DG Punst1 KISRIRTWARTPPSRT--TELPR-P-FERALGVAGVTGWIVFYIFAANQEKLSSSVVRQILDNIRSPELKEVLG--DAIRPEPWIAGSVSNMQGHADVSFRVKGHKGA-GTLYFTSIRKAKVLRFRVITD-DG Rhior3 SRLKP-------LLLNTT---LFAP-PPPAGAGVGAVVWAVGLGAALNHQRLSSSVVHGTLFTVRDPRVVALVG--DRVNYAPWITGTVNHLKGKIDIAFDIKGSSNERARVHFVSRRVG-TLRFSVVRESDK Rhoto1 ------------------------E-LKSGLAVAAAAAWGAFLIYATNEERANSSVVRSLTFQLRWPAVKEFLG--ENVKIEVRIKGSINMLAGRIDVQFPVRGSKAR-GTASFTSIRRGKVLRWKITRE-DG Rozal11 ------------------------------------------------------------------------------------------------------------------------------------- Sacce1 K--GLTPSAAKAVLVRGSAEDE--P-TTEGFLLFSVAIGSALSLI-FNYEKTESPIISNTLYYIRSPATKNILG--ESIEFDPWVYGELNSVKGRINITFYIKGDKNVTGTVRLVADRNTHIHEWSVTAA-GQ Salro ------------------------------------------------------------------------------------------------------------------------------------- Schco3 -----------------------------AFAAVGVVGWAVFFTYVTNQEKVTSSVVQQMLRSMKSEELHEYMG--DAIRPVPWIHGRVNQINGSIDLSFKIKGSKAF-PLLY-------------IVVD--- Schpo1 ----MKSLDYGHCLTVKS------E-LSSILFAAFCLLWGTCAVLAIQYGKQNSNVTQVVMYRVQSKEAQDLLG--SNIDFKPWVPGKLHKRQGFIDINFEVSGSLAS-GTVHYQSQRFGPELDCTLTS--NG Sorma RMAL-RALARSSRAPQK-TSAPRPD-VQTTFPIFFGIVAATSIAI-FNYQKLSSPVVSSTLYALRNQRAREYLG--DEIYFKPWISGEMNQLHGRIDIKFNVKGTKRT-GVMRFASFRPTPTTEWSLETE-DG Sphar ------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ------------------------P----GLAAVGLGWWAQTVYGGINSQKAHSGIFKAVMFHLRDEAAQSLLG--DNIHHDPSVKGNVNMLKGKADIEFLVEGSKGT-GVVRFRG--VRGSQLFTLKSP-EG Sporo1 ---------------------------------LSALCWGLFLAYATNAERANSSVVRSLLFQLRWPAVKEFLG--DGVKIEVRIKGNINMLAGRIDVQFRVRGSKGN-HRNPF-------LL------S-SN Stehi1 ----MRSLSRTIPLRTRTGELPR-P-YRRLLSTAGVSVWAVFLTYMANQERLSTSVMKRIVTTIKSEEVREVLG--EAVRLEPWVTGSVSMLQGSVDLSFRVKGHKGS-GTLYFTSIRKGKILRFKIIAD-NG Tapde11 ------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----MNIRFLSNPSRQTPKASPRQK-LRSGVGALCLSACVGFVLWATNTERLASSVLRQVTFQLRSAQVASVLG--ENVRLAPWISGSINNMQGHVDLSFRVRGSHGA-GTVYFTSIRPKQIVRYKIITD-DG Trire2 RRLV--AASRSQPTNPNSTPAPKPD-VGQTLPIFLIVVAACSVTI-FNYQKSSSPIISSTLYALRNPEANRLLG--GEIYFKPWISGEMNQVKGRIDVSFAVRGKKAS-GVMRFASHRPSPTTVWSLTMD-DG Umbra1 TRASTLSMA--RAMTLNT-SRRYLE-APRGAGIVGVSLWIGGLSYAMNYQRQSSSVVHGTLFTVRDPRVRALLG--ENVGYAAWIDGSVNHLKGQVNIKFNIKGDNGQTAKVHFASRRDG-TLVFNVVRE-DG Ustma22 -----------------------------VTVGMALGSWAVFSLYATNTEKLSSSILKSVISQVKSPLVVDLLDTHEPIVLKPHIQGSVNMMQGRIDLAFKIHPRNNT-ATVYFTSIRPHKILRFLVIHNHSA Walse1 ------------------------K-NKNLLLSFSCLSWFGFIKYSNNQERLNSSIVKELIRQSKHPTTRDVLG--RDIRLYTYVNGEISMMKGKIDISLDLKGSIDQ-GKIYFTSIRNSKILRFKLIDNHNN Zygro1 ----------SRSLTRS-TQST--P-FAYTFAAFSIGVVAALAII-FNYEKTESPIISNTFYHLRSPRTRELLG--ENIEFDPWVHGELNQVAGKVNIRFNIRGSKGTKAVVRLVANKDNEIREWSLTAD-DE [Cluster3326.fasta_al_trimmed; alignment length = 66] Allma1 ------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------ Aspfu1 DLSGNTYWERYRRIVK--VTPQWHQWLRYVRADPPSLEEQQQDVIRQIQIKAQFADMR-------- Aurde31 DLQGNRFYEKSRRVVKRGLPAQWQAWLSHTRLEPPTIEELQYDEIRQERLRVAQLQAR-QTETWTP Batde5 DLEGNMYFELPRRSIENAIPIQWQAWLRHTRETAPTVQELQDEIARRLYIQA--LEIQFVPESWQP Botbo1 DLQGNQFFERTKRKVEGNLPIQWTAWLSHTRPHPPTLEELEHDLARRHRVLAAILETRAEPESWAP Botci1 DLQNNSFWERMRRIVQ--ISPQWHQWLRHTREDAPSIEELVGDIARQERLKARKADERWQPQAWDP Caeel ------------------------------------------------------------------ Canalb1 DLYGNTYWERLRRKLEKTIPPQWLQWLRRTREHSPSLNELIEDQIRQQRIKAQQADENIESTTIKP Cangl ------------------------------------------------------------------ Capow DLDGNEYYEQTRRLVDDTVPVQWESWLRRRRIAAPTHDELLADRARRETLAVMDLQLKFEPEAWQP Catan2 ------------------------------------------------------------------ Cioin ------------------------------------------------------------------ CocheC53 DLHGNTFWERNRRIAK--ISPSWMQWLRHTRFDPPSIAEQQQDVARQERIKAAQADAKWQPQGWAP Coere1 DLDGNLYFERSRRRV-KIIPVQWQAWMRHTRIQPPTVAELVLDMRRQERVAARRL---FSPEGWHP Conco1 DLKGNYYYE-PRRTVKAPLPVQWISWMRHTRHHPPTIEELMNDEIRKQRTLVKKLELLFEPESWSP Conpu1 DLEGNKYYERTKRTVKRRLPVQWTSWLTHTRPHPPTIAELQADVMRQERVRAAIIDARDEPQAWAP Copci DLEGNKFYERPKRTVVKRLPIQWSAWLSHTRPNPPTIEELEADLQRQIRVKASLIEAK-ETQSWTP Croqu1 DLAGNRYYQRPKRQVENRLPPQWAAWLSFTRPHSPTIQELQNDRIRQERLQVRQLEQAWAPQSWMP CryneH991 ------------------------------------------------------------------ Crypa2 DLQGNTYWERWRRIVQ--VSPQWHQWLRNMRERPPTLQEQHHEARRQAQMKAAEADARWQPQGWTP Debha1 DLHGNTYWERLRRKSEGTIPPQWLQWLRRTRQKAPTLEELTNDQLRQHKMKAQQADEKIQAATINP Dekbr2 DLKGNTYWERPRRIWHDKLPIQWLQWLRYSRPKAPSLDELIKDEERLETLRVKLKGQ--------- Dicdi DLHLNRYYQKVRRDVDRTIPSIWNRWLAFRVSDPPTYEDVLKEDERQRSIKAKIFEEEIPKQ---- Dmel ------------------------------------------------------------------ Enthi ------------------------------------------------------------------ Falba DQYGNEYYEPRRKVVPGSLPVQWHSWLTHRRAVPPTLEEIARDEQRRLDIQARLIDQHYQPEAWTP Fomme1 ------------------------------------------------------------------ Fusgr1 DLQGNTYWERWRRIVQ--VSPMWHQWLRHTREEPPTIEEQQDDVVRQARMKAAQADARWQPSAWTP Galma1 DLEGNKFYERPKRTVQKRLAIQWSAWLTHTRPQPPTIEELQVDMNRQQRVLVALIEARSETESWTP Ganpr1 DLEGNLYYERAKRVVEDTLPVQWRAWLTRRRPDPPTKEELLAEVRRRHILEVKALEEKFRPGEWTP Gloin1 ---------------------QWNSWLRHTRYDSPTIEEIVLANKRRDLIIAKKLDQEFEPETWNP Hisca1 DLAGNTFWERLRRIVK--VSPQWHQWLRYARQDAPTIQEQQNELLRQERIKAKLADERWQPESWKP Klula1 ------------------------------------------------------------------ Lacbi2 ----NRFYERSRRTVQKRLPAQWSSWLSHTRPNPPTLEELQMDIARRERVLAQLIEAKSEAEAWAP Lenti61 DLQGNRYFERTKRVVKRRLAVQWSSWLTHTRSHPPTLEELQADLERQRRIQATMIEERDEPHSWQP Malgl1 DLEQNTYMERTRRVVKKEMPIQWDAWMRHTRQHPPTIEELLKDRERQRIVQARVLAIRIRPGR--- Mellp23 DLAGNRYYQRPKRRVENRLPPQWAAWLSFTRSVEPTIQELEADYLRQQILFVNQIEANWTPQSWNP Mnele DRHGNSYFYRPKRIYQIDIPPAWQAWLTGTRTDPPEDHEV------------------FQPGSWSP Monbr DGNGNKYYIRTTRVVEDAVPAEWSAWLSHRRAEPPTDEEINRNRMITARTLAQELADAYQPAGWKP Morel2 DFEGNLYFEYPRRTVEANISVQWQAWLRNTRKDPPTLTEIQRDEARKLLTVAKALDQAFEPQAWSP Mucci2 DLKGNEYWDRMKRWVQDKLPVQWQAWLRHTRTVAPTIQELVQEERRKALVQAKALDEEFSPGEWNP Mydma DHLGNKYFEKKVRSFEGFLPPEWETWLSWRSHHPPTVEEIEKRITNTVLIKAKADDESFEPEAWKP Neucr2 DLAGNAYYQRWRRIVQ--VPPSWHQWLRYTREDPPTIEEQEAEVARQQRIKAKMADEKWHPKAWDP Orpsp11 ------------------------------------------------------------------ Pench1 DLAGNTYWERFRRIVR--VTPQWHQWLRHVRQHPPSIQEQQQDLIRQAQIKARLADERWQPEAWSP Phybl2 DLEGNEYWERVKRWVQSHLPVQWHAWLRHTRPTPPSIQELVMEERRKAIVQAKKLDDAFVPGEWQP Picst3 DLYGNTYWERLRRKMESSVPPQWLQWLRRTRNHPPTLEELINDQVRQKKMKAQQADSKIQTTTIKP Plicr1 DLEGNKFYERKRRTVEKQLSAQWHSWLTHTRPHPPTIKELQADVLRRQRVLASLIAARYEPQSWKP Polpo DKLSNRYYKKEKRTIERIIPVQWSSWLGFRRDDAPSILELEQEEYRQEAIKSKKLEEEIY------ Pucgr2 DLAGNSYYERPRRFVNHHLPPQWSAWLSFTRKQPPTIDELEADQLRLSQLRVRKLEIQWQPQSWNP Punst1 DLQGNRFFERPKRMVKNTLPVQWQMWMTHTRRNPPTIEELQADLVRRERVAVALLEQS-QPQPWSP Rhior3 DLAGNEYWDRMKRWVQNLLPVQWQAWLRHTRQQPPSIVELVQEEKRREIVLAKALDEEFTPGEWNP Rhoto1 DLNGNEFFEQAKRYVEKSIPVQWSSWLRRTRRDPPTLQELQSDVQRQLKLQVQRLEQEHQPAGWTP Rozal11 ------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------ Salro HGPCTFYVEHTTAAIQNSVAPEWAAWLNYQREEPPTEDEIQRNRLQLQQTLAARLEAEFQPASWMP Schco3 DLDGNRYYERTSRSVRKLLPVQWSAWLSHTRQNAPTMEELLADAERQRRLQVAMIEARDQPEPWNP Schpo1 ------------------------------------------------------------------ Sorma DLAGNAYYQRWRRIVQ--VPPSWHQWLRYTRDEPPTIEEQEAEVARQERIKAKMADERWQPKAWDP Sphar ------------------------------------------------------------------ Spipu1 -----MYFERTRRTIEELIPVQWQSWLRHCRDDPPTLAELREAEAQRLLTIAAELDRKFEPGAWTP Sporo1 ------------------------------------------------------------------ Stehi1 ---------RTKRKVVRRLPIQWSAWLSHTRPDPPSIEELEADIIRQQRVLARVIEARWQPQSWQP Tapde11 DLDGNKFYER--RTVQNNVTPQWMSWLRYTRPNPPTMDELRGEVVRIQSTRAQLISRRWQPEAWNP Thetr ------------------------------------------------------------------ Treme1 ------------------------------------------------------------------ Trire2 DLQGNTFWERWRRIVS--VSPQWHQWLRHARRDPPSLDEQRAEAARQERIKAAQADARWQPAAWDP Umbra1 DLSGNEYWQRPKRWVKDKLPVQWQAWLRHTRPTTPTIQEIIAADQRRLMIQARQLDEEFVPGSWSP Ustma22 DLAGNSYLEHTRRSIQRSIPVQWVMWLRHTRRQAPTIEELVQDRQRIELTQAARLALEIRAGRDEQ Walse1 DLEGNKYYERPKRTVKREMPAQWKAWLRHTRFEPPSIQELELDLLRIQRTQAARIEAA-RTQEWTP Zygro1 ------------------------------------------------------------------ [Cluster3327.fasta_al_trimmed; alignment length = 140] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 --KCL-ADSK---PGILNLIFFHRYFPSI-RPTTFDV--LDFTLPAIDD-AELETLIESRISALV-RQHTIAVEFYEVCWEVWNLDVTIPRTESERKAMENMLALKI-LAVVNRDKDHI-PPITTSDPFPYRIVLNRFGL Aurde31 I-DIT-VDVKDALRALLHAILFHRLFGSI-KPFYFDV--LDVTIPGIED-SEVDRLIDNRVGALY-RAMDVLVILSEYTWEQWVINVEIPKNDDERRAVSDTLVRTILDHTSSEKGRAAVPPIRQNEPFPYRIVA----- Batde5 --MLKSVEAKEVLRGILQSIMFHRTLSNT-RPIDVHLDSLNITYACLDD-KE-------------------SVMFFEICWEKWDITLTPALTEQLQALLVKSFLVKI-SDKANEEKDHI-PPMLTS-PFPCQITLTITNL Botbo1 V-DVT-IETKEVLRALLHAILFHRLFGTI-KPTTIEI--SEVTFPAVSD-SDIERLVVQKVDTFF-RALELLVTFSEVPWEEWVINASVPKHEHERSTLPGSLLRTILVRASSESGRQCVPPIVTAGPFPLRITV----- Botci1 -----------------------------------------MTLPYIEN-VEIETLIDQRTAALV-RQLDMAVQFFEVCWEQWTLDVTLPRTESERNAMEAMLAMKI-VTTVNMEKDHI-PPITTSEPFPYQITIARMSL Caeel -------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 I-NVI-AELRESLKGIIWTIFFNRLFGPI-TPVTNEF--MNVSYPMANNLPDLDSLIDEKVNRIL-------VQFLSVVWESWLINVESQVSNGE-KNVQTSILTRI-YDIADKFKEHI-PPITSLDPFPYKIIITYIKK Cangl -------------------------------------------------------------------------------------------------------------------------------------------- Capow L-AIT-TDTREAVSALLHTILFHREFGRA-RPVDVECESLDLTYVRVDS-EEVAATVNEKVAQFA-KMFELSLSFYEVNWEQWNVIVTQFLSEAERSALTSEIVSTI-IFICNSKQDHI-PVVKNDTPFPFEIILDMIKR Catan2 -------------------------------------------------------------------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 L-DIF-ADVKDVVKAILHTIFFHRYFTSI-SPLTRDL--LDLTLPAIDD-VDLETLIEQKTFALV-RSIDIVVQFFEVCWEQWTLDVTLPRTETDARAMTKSLAHKI-IAIVNRDKDHI-PPITTTDPFPYQIVVPRIGL Coere1 Q-TLE-LEVEPVVKSVLHTILFHRYFGNV-SPRDNYI-LSSITYTSVDN-VDVLSAVDEKVEELM-QNLSISLYFTEICWEEWIINVQSQQTDREAINAENQAIFHV-IQEMDKSKEHI-PLIANSQPFPYHISVLMIKR Conco1 -------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 I-DVV-LDAKEVLRGVLHSILFHRLFGTV-VPQTFEV--LDVTMPGISD-ADMERLIDEKVNAFW-KGIEIVLTFSEVPWEQWVVNAELLKTERDPATLSNSLLRVILTHTSSLRGRTAVPPITKVDPFPLKMAV----- Copci I-DLI-LDAKDVLHGVLHSILFHRLFGTV-KPTTFEV--LDVTMPGVSD-PEMEQLVNTKVDAFW-RGIEIVVTFSQVPWEKWVINAEMR-NDSDYVTLANTLLQTMLTHTSSERGRAAVPLITNATPFPIDITV----- Croqu1 H-EFV-IIARDVIKAILHSILFQRVFGSI-QPKTIEV--LGLTFPQVIE-PGTERLVEERTESLF-KALDLSLRFLEVIWERWEIGFTI---EGERKSIKSQLLSHQ-IGFVVSQRDHI-PAITSSEPFPVDIII----- CryneH991 ----------------------------M-EPETLEL--LESHISCAPN-SIISREISNKIEEFARQYLEMAVVFLQVPWEEHLITLNF-------KTLSNPLLLQI-ATFCLEQKAMV-PPLTGTTNVSYQIMIAAFGR Crypa2 L-DAF-ADVRDVVRGILHTIFFHRYFPTI-VPQSHEV--LDLTLPYVAV-PELETLIDARTAALV-RELDVSVQFMEVCWESWTVRVTVPRTESERKAMESTLVMKV-ITSVNTYKDHI-PPITIMGPFPYSITV----- Debha1 L-NLT-AEVRESLKGIIWTIFFHRLFGPI-TPTTNEF--LTITYPMTSDLPDLDSLIDEKINQLIKKKFDVVIKFLDKLWESWTINVKCKESVGDKQNVAISIMRKI-IDIADSQKDYI-PPITSLDPFPYSIDVNYIKK Dekbr2 L-KLV-TDVQDYLKGILWTIFFHRLFGQL-TPEDGKN-YLGVPYPVFSC-PDLASLIDSKASTIW-EELSIVIKFYKNCWERCILKVTI----NKHRDYNTQLMFKI-VEYMDKSKDHI-PPIPSMDPFPYKVLFNFLRK Dicdi LKEIN-LQLKEVVQCILHSILFQRSLGTV-KPKDTTLDCVDFSYVKSDD-PSSSKHIEDKSEELL-TSIMISISFYEVCWEQWIISFQL-------KSLFSQLINKI-IENVNQEKSI--PPITSSNPFPFSIQIMFKPP Dmel -------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 I-DLI-LDTKDALKALLHSILFHRLFGTI-KPQTIEV--LDVTMPGVKD-MQTEMLIDEKVDAFW-KGVEITVTFSEVPWEKWVINAEVPKAERDRTTLSTSLLFTILTYTASERGRTAVPPITNSSPFPFKISV----- Fusgr1 L-DVF-TDVRDVVKGILHTIFFHRFFPSL-VPQTREV--LDLTLPYVDD-DELETMIEQRVAAFE-RQIDLVVQFFEVCWECWTIKVTVPRTESDSNVTLVMLAPKVSASYAAREPDTAESPTQTLE------------- Galma1 V-DLI-LDMKDALHGVLHSILFHRLFGTI-KPQTFEV--LDVTMPGVSD-PETERLVYEKVDTFW-KGIEIIITIAEVPWEQWVINAELPKTDLDRASLASTLIHTMITYTSSEKGRAVVPPITDATPFPFKVTV----- Ganpr1 V-PIS-VELRESLRALLHSILFHRLIGPI-RPRVLELSSLDVSYARIDD-SDIERTVEERITTFV-KALDLSVSFLMVCWERWDVGVKLARNDAEHRVLERDLLIRI-SQLSNDTKEHI-PAVNSLDPFPWNIVISFFR- Gloin1 I-ELT-VDVADILRGILHTILFYRVFGNI-KPKEVDV--LDITYSAIDD-PEIEKKVDDNVDQFM-RILEIAVMFHEICWEQWAVTINTCRTDGETKEMSAQLFLNI-IRFINDKKDHI-PPITTLEPFPFQIVITMLKR Hisca1 L-EVF-ADVKDIVKGILHTIFFHRYFPCI-RPTSLDV--LNLTLPAISD-VELETLIDARVNALV-RHHLIAVQFFEVCWEVWTVDVTIPRTESDRNAMEKMLAFKI-VSVVNKDKDHI-PPITTSDPFPYQIVLNKFGL Klula1 -------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 I-DLI-LDTKDVLHGVLHSILFHRLFGTV-RPRTFEV--LDVTMPGVSD-PEMEQLVSEKVDTFW-KGIEIIVTFSEVPWEQWVINAELPKSDRDCATLASSLIHTMLSHTSSERGRSAVPLITNAAPFPIKVTV----- Lenti61 I-DLV-LDTKDILRAVLHSILFHRLFGTV-KPITFEV--VDVTMPGVDD-EEIKQLVEDKVDAFW-KGIEIVVTFSEIPWEQWIINAEIP-SERERADLASTLLQTMLTHASSERGRAAVPLITNASPFPIKMSV----- Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ----------------------------M-Q-------------PQVLE-PGTESLVEERTESLF-KALDLSLRFLEVIWERWEIGFTI---EGGSKSIQSQLSSHL-VGFVLSQRDHI-PAITSSDPFPVDIII----- Mnele -------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------- Morel2 V-ELT-VELKDALRAILHTVLFHRVFANI-KPRDMDI--LDLTIPIIDD-PEVDKLVDEKIAAFV-KVVDIGIMFYEVCWEQWAITINVNINEKDKKNMEKALFLSI-LRTVNERKDHI-PPITTSDPFPYQIVISMFKR Mucci2 L-EMTSLPVKDVLRGLLHSIFFHRLLINV-LPRELRV--LNTTVSITDS-PDVENLIEEKIAEFL-HNSNLAVLFYEVCWEQWNITLNLPKSEQEKKSVENQFLMKI-LKIVNDYKEHI-PSITTTEPFPYQIAITMIKR Mydma -------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 L-EAF-ADVRDVVRGILHTIFFLRYFVSH-EPKTRDV--CGLELAYIPD-AEIETLIDQRVATLV-RQLEITVQFFEVCWENWTVKVTVPRTESERNAMESTLVFKC-ITIANTHKDHI-PPITTNDPFTYQIHVTRMGI Orpsp11 -----ESDLAEVVKSVLHTIFFHRVMTLV-TPIEVQI-GPGIQYVKVND-IELEEIINKKTLQFI--QLDIEVRFEKIIWEQWNLDFFV-------QKTFENLLIKI-SQYANTYKNHI-PQLTEQENFPYEIIIKKLRK Pench1 L-EIF-ADVRDVLKGVLNLIFFHRYFPSI-RPVTFDV--LDFTLPAIND-ADLETLIESRVSSLV-RQHLIAVEFYEVCWEIWTLDVTIPRTESERKAMGNMLALKI-LSVVNRDKDHI-PPITTSDPFPYRIVVNRMGL Phybl2 I-EMAQVPVKDVLRAILHSIFFHRLLINI-TPRELRV--LETTVSTTDS-PDVEILIEERVNEFV-QNIN-------ACWEQWSITLNLPQTETERRSVSRNLLLDV-LKMANDYKEHI-PSITTTEPFPYQMATTMIKR Picst3 L-QLA-AEVRESIKGVIWTIFFHRLFGPI-TPVTNEF--LNTTYPMAANLPDLDSLIDEKISRLI-RQFDIVIKFLDKVWEVWILTVTCEPRDSNTNTIEISILNKI-IDIADTHKDHI-PPIMTLDPFPYVIEVEYIKK Plicr1 I-DVI-LDAKDVLRAVLHSILFHRLFGTV-KPQVFEV--LDVDMPGVDD-PEMEQLVNEKVNVFW-KGIEIIVTFSEVPWEQWIINAEMPKSDRDREALSSTLLHTMLTHTSSERGRTAVPLITSTAPFPIKMTV----- Polpo L-EIN-LQLKEVVQCLLHSILFQRCLGTI-KPKEATLDCTDFTFTKLDD-QQTTKHVEEKSEELL-SSIILSVSFYEVCWEQWIVTFQL-------QALFQQLIQKI-IVIVNQDKNI--PPITAKDPFPFTISIVFKPP Pucgr2 H-DFI-ITSREVIRTVIHAILFHRVFGSV-QPKEVEV--LGITFPQVVE-SEIEDLVNQRTERAV-VALELSIRFLELVWEKWEIGFKIAKSDKSSRSIQHQLLTRL-IDFVLNERDHV-PAITNSDPFPVDISI----- Punst1 I-DLT-LDGKDVLTAVLHSILFHRLFGCV-KPQAFEV--LDVTMPGVSD-PDIEQIIRDKVDFFY-KAVEVTSSFTKVPWEQWTITATIL-SSRQKAELSQTLLTTILMHTSSEQGRSAVPLITSASPFPLKITV----- Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 A-SIA-VEVREVARAVLFTILFHRVLGTLSKPSTLEV--CGVTFPAPAE-RELEELVERKVDLLV-KALSLFVTLYPTAWEGWCVEFEVGGTRSRRERLRTQLLLRS-LHFTMTKTSHI-PPITTAEPYGVVVLV----- Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------- Salro I-KCELLRAYEIIEAFLHTIFFFRTLEGTFKPQDASCPSLAVTYAQVPS-AKLRSSIDAIATQFH-EKLQMNLCFMTEVWEKWEIVITVSVSEAEANAVIEQL--EI-IYNVTTWTRHL-PHVSKKAPYHYDMKINFVQR Schco3 V-DLV-LDARDVLNGVLHAILFHRLFGTV-KPQTFEV--LDVTMPGVSD-ATMERLVQDKVDSFW-RALELTVTFSEVPWEQWVVNAELPRGERDRATLTNALMMTMLTHTASEKGRAAVPLITNATPFPFRIAG----- Schpo1 I-ELK-IGAAEVVKAVLGVILFHRQFSTV-PARTIDV--LDITVPTLVG-AELNEQLATKAAEFI-DTIRMILLLYEIPWEQWILHTTI-------SYQESSLVEQI-VQAVNLRSLSYLPPVAMDSNYPYEIVTSLLKR Sorma L-EAF-ADVRDVVRGILHTIFFLRYFVSH-EPKTRDV--CGLELAYIPD-AEIETLIDQRVATLV-RQLEITVQFFEVCWENWTVKVTVPRTESERNAMESTLVFKC-ITIANTHKDHI-PPITTNDPFTYQINVTRMGI Sphar ------------MES-----------------------------------------VEDRVQDFC-DALDIRITFSEVVWEEWTIRTQLPRTDTERRQVEEQITERI-IHACNSKYNHI-PRVPNSSPFPFEITLDYYRK Spipu1 L-ELV-VDLAAVMKALLHSILFHRRFTSE-RPMEIDLDALNVTYARLED-PELERAVDEKVRMFD-KALEIAVMFFEVCWEQWVITITISRTEREHRALQKDLLTSI-SQMTNEQKDHI-PPIVNNDPFPFQIVISMFKQ Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 I-DVI-LDTRDVLRALLHAILFHRLFGNI-KPQTFEV--LDVTIPGVAD-PDMEKLVNEKVEVFW-KGMEVSVTYSTVPWEQWNINVEVPKSEQDRRTLPNTLLQTMLIHTSSEAGRAAVPPITNSNPFPMKITV----- Tapde11 L-TIQNCEVKEVTKALLHTILFHRQFGQI-SPKTQEL--LDLTIASIDD-GAVESMVEERASAYI-KSLHLVVEFYEVCWESWTLNFELSRSEPERKVLVSQLILRI-LTLVNKRNEEYIPPIPYSESFPYQIII----- Thetr -------------------------------------------------------------------------------------------------------------------------------------------- Treme1 L-ELT-VTLKPTLRALLHAIFFHRLLDNV-QPETFEI--LDVHVPSVPN-PILEKDINTKVDQFYEETVLLAVIFLQVPWEEHLITVHL-------RSTNQSLLLQT-LTFCAEKKGNV-PPLSGNSFLSHQILI----R Trire2 L-DVF-SDVREVVKGILHTIFFNRFFPSL-APRTHEV--LDVTLPYVND-NELETLIEQRAYALE-RQLDITVQFFEVCWETWTIKVTVPRTDN---------------------------------------------- Umbra1 L-EMTAVSLKDVLRALLHSIFFHRLLINV-TPREGHF--LDTTVSMTGN-KEVEDLIEEKVVEFY-MGMSIAVLFYEICWEQWAITITVPQSEQEKKSTERQLLMKI-LNIINDHKEHI-PSITTTEPFPYQIAIAMIKR Ustma22 H-RIR-CELERTAQVVLHTICFHRFLGTV-KPAYVDA--FGMTFPAIAD-AQLDQLIRQRTSQLM--ATTLTVYL--EAFERWTITFEL-----KQESMERELVDQV-LRFVGNNKAHL-PGVTSAQPYPVQVVV----- Walse1 L-TIT-VDLEDVCAGILHSMLFQRTLGNF-KPKELAV--LDVPMPAIES-ASIGQLVQRYAQELS-----LALVLAEVPWETWIVNFNISKSENHKTNTQNDLLLQI-LAFADERKDHI-PPIMTADPFPFHIVVAEVNR Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3331.fasta_al_trimmed; alignment length = 194] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 -MALVQY-SGTESD--EESEEKPDRVSSLPP--LPTAFDDPSLHGGRKRVIPHVEGNWPTHIYLPSKAELT-GILSQVEVKLLHISLSRPVVLRTEQRQPFMDMFQTESVVPAFSVS-CSLDWVSNYERTRWFLVLRVTKPLS-LSNRSLAHFGQPSLYASHCFHVSLA-WSLRI-----IHFDCVKVKIGNNI Aurde31 ---LVAYSDSEGEASDDELQTEPTSRKKLPA--LPVSIDDPTEHQGRIRTHRHVDGLYAAYVYAAVRLEDAPEFIARATQHALHISLSRPIYISANQRDALKRVVRDAAKHRPFRASFAEFAVLENDERARAFLVAEIGAGTR-EIDASLVSMGHEPYYAEPRFHASFA-WWLELLDELRVDVGGISLRIGKAV Batde5 PSTGSTWP---------------GNKKKSNS--LNTDRLKPNAIQVPVRTVAHIEGNWATYIYIPIELQED-ELKDWIKQ--LHVSLCQTAYLKVFQIDRFMALLEQIGLQSRFTVSFNGVSSYVNDEQTRSFVGMDIGHGVQ-CVDLALTAFHQPPFYKNPRFHASIV-WSPSIPDSLRFLVRSVVCKSGNKL Botbo1 LPSLVQYSSSEDEAEDASSSASDS---ALPA--LPVSFSDPTAHQGRRRLQPHVDGQFAAHVYISVPLN-RK-ILQNALALALHISLSRPIYLRAHQREEFKRAIRTASESAPFIASFACFTSFTNDERTRTFLSLEIGAGSS-ALTPHLNFLHQKTYYDQPRFHASIA-WALDFVEGLELKVEEVEVKIGKEV Botci1 -MALVDY-MSSDEE--VVDEDLPSSSSELPP--LPSKFDDPSLHGGRKRVTPHIEGNWPTHIYIPSTIEFD-SLISQVESFKLHVSLSRAIGFSKDVKDTFLTSFEQSSGVRPFEMG-SGLAWVPNYEKTRWFLVLRVNTPLH-VSNKVVEEFGQPPLYASNAFHVSIA-WTLRL-----IKTEEIKAKIGNAV Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ------MSSSAASAAA----------------------GD-----GRVRTLPLTRGVFATHAYAPMQHDDQDELLEGVDALVMHISVTRPLVVSHAKLSPLLDRMRARHQHGGIVVDLADVEFFVNDERTRTFVSLMVRRGVK-QVDAVLRDFPLQEFYDEPRFHLSVA-WCVAALSSLAEKGVTVNATLSQQI Catan2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin LEMLGEYSSSSDEESITASSQK-----------VPDAINDPTKHQGRVRSFQHVKGNWATFLYIHCN-----ELRSYVEDL-FHLSVSRTSAIPH----HFIEPLVELSPV---ILNFCDLKFYVNDEKTRSFCGFEVTSPVD-HINKPLKDYKCDSYYENPSFHISIS-WTLKQLEIFQFEANNLVCKCGNRL CocheC53 -MALVAY-PDSASD--TEHDKTP-----LPP--LPPAFDNPDLHGGRRRAVPHVQGNWPSHVYLPTQRESI-NLIQHVKSVLLHVSLSRTLQIKTEDRETFLDTLGTRCAVPAFNFE-QGLKWVPNFERNRWFLVLAIKRPLH-ACNQAAKNTGHPALYTSPYFHVSVA-WNLKI-----AVFDAVKVRIGNAV Coere1 -----------------------------------------------------MAKGW--HVQD------------------PHISLTRAFYVQEHQIQPFVRAVEAVADMSAFGVGFGGMQALANERGDRVFVAVAVKHGLE-RVDRVMERFGKRVFFRHAQLHASVV-RMEEMVQCLE--IDSLECIFGNRR Conco1 MEGLVNYSDSDDSDTSEVNNKTESNKRKLPS--ISDLFDN-----GKKRTIPHRRGNWATHIFLEITISTSTNLISKLKDLNLKVSLSKTWYLAWSFHDKFLIELETLKGIKKFIVNYSNWQLFSNEDFSRHFISLNIEKGGL-KVDQ---------------------------------------------- Conpu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci IGLLADYSSS-EEE---EHDEQKAKRKKLPA--LSESIDDPALHQGRIRTTPHVEGQFAAHVYVSLSLKGNPKLLKEVLRDALHVSLSRPVFLRAHQREEFKRSVRNAKEQSPFAISFAAFSELTNDEKTRTFLVLEVGAGAS-SLTSVMKSFRQKEYYESPRFHASIG-WALTLLPFLEFHVDQVTVKIGKEI Croqu1 ----------------PTQDTKA-RRRVLPP---PCFSDDPTLHQGRKRSKPHVEGDWPTHIYLSLEIPDE-KLID---KVVLHLSLSRPLALRAHQRQTFRSSLTHISNAEHVKFHFARFCSLVNDDRSREFLALEVGSGIE-RINWVLSSFCLEEYYSKPIFHSSVC-WRLNEIKDLDWLIEDVKLVIGKSV CryneH991 -----------------------------------------------MRSRPYVDGEYNTHVYLSLSISWK-KILETII---LHISLTRPVPLRRHQIQPFRDELASLGQICPFKLSLAYYNEVTGGGSNRAFLALRVGAGVDVVLDPTLKKIHRPTYHDNPEFHTSFA-WTLEDLNRVNWTISSVEVKIAKEI Crypa2 --------------------------SPLPP--LPPSFDLPSLHQGRKRVIPHVPGNWPSHLYAPDPIHHA-SLLDALTTTTLHVSLSRPFVLRTSEREPFLATLERASGVRAFVLV-DGLAWFRSAEGGRSFLVLRRRTKLG-KCNDLVAAYGQPRLYA--AFHVSIA-WSFAVFARKEIPVNGVKVKIGNVV Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi MEFLKHYEDDEDQDDETKDENVNNVIDEIPD--LPLSFDE-----KKTRLFEHVEGNYPTFIYFKVPTKSRNELIEQVKEIGFHISISRTFPIREHHIETFTQELKKLKNQRSIDIQLKECCVFINDNQSRIFLSIPINQSIE-RIDSCLSLFKFPKYYDNPEPHLSIS-WSLIIRDNLKFKVSRIFWNIGKTE Dmel -MALVDYGSSSASE--TENIQTP-------P--KPEEFDDPAEHGGRMRSFKHERGNWATYVYVPA------ACVDQLEEFQLHLSLSRTVVLQYHQIDEFSRSLQSSS--AGFAAT-QGLRIYTNEERTRTFIAAPLDAALQ-PIDQVMLDYRLQQFY-PASFHVSLL-WCVEL---KELAVNEVHLKCGNKD Enthi ---MTDHETSTQKAVS-------TDTNDLFQ--LLNELRSREKKEGRIQQRPHKIGEYPGSVYIPIEIKNK-ET-NQFSQDFLHISLTKEFSLREHQIPLFVQEVRK--RLPTFTITFGQLELLLNPEQNTEFLSIQV--TID-LLDTVMMSFNLEKYYEERKIHSSLM-YRT-------FKPATIKIRLGEIV Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 VN-LVSYESTDEDEKE-------SGKRKLPK--VDPSLSDPSRHQGRIRAIPHVEGQFAAYVYVPVCLKANTSLLDEVVGRSLHISLTRPIYLRHHQREELRRAVKMARAVDPFTASFSSFSVFENDEHTRVFLGVDIGAGSK-SIEPTLKLLHQKQFYIEPRYHASIA-WSLSLVSDLNFEVNSVCLKIGKEI Fusgr1 -MALVDY-SSSGS----------AGASSMPP--LPDTFDDPSLHQGRKRHIPHVVGNWPSHVYTPSTEQHG-TLIADIEEHVLHISLSRPLSLTTSAKDEFLDKITESSGIAPFAVK-QSLAWFRSPDSDRTFLILRVASGLL-RSNSVAAQFGLPSLYAGGAFHVSIG-WTFQLFKQPKISVLGVKVKIGNVV Galma1 NLTLVSYSSSDEED---IAQEMPMKKRKLPP--LSSSIDNPALHQGRIRTTPHVDGQFAAHVYVSLPLGRHSKVVQAILCDALHISLSRPIFLRAHQREDLKRAVKNAKAHKAFIVSFAILSELINDEKTRTFLTMEVGAGAN-SLAPAIEAVRQQAYYVKPRFHASIA-WALEVITTLNFTVESITLKIGKDM Ganpr1 -MSLVDYSSDEDVHTK-------TGTGSLPSAALPEGSNHPQARV-------HSQGDWTLHSLHPVSLSEDQSLVERIVARALHVSLTRPVILRIFQLEAFTKGLEMASKRKQFRYSLGSFKTYQNYNKSQTFLALDVLGGVS-DSDAVLATFQLPQYYATPSFHVSIA-W--NLLRTLS---GCVECKAGNKM Gloin1 MSGLVEYENESDNENNESEERK--PRKDLPP--LPSDFDDPSKHQGRIRSKPHVEGDWATHVYVDVTLTEE-HIIN---K-ILHISLSKPLFLKYHQIEHFWNKLRNFLNWKRFSLSFANITSFSNDDKNRSFLALEVGKGVD-HVNKVAEDFRQKPFYENPRFHASIL-WALDAIKETEFNIENMVCKIGNKT Hisca1 -MSLVQY-SDSESDE-PRRDTHPSGNTTLPP--LPSEFDDPSLHHGRKRIMPHVAGNWPTHIYLPAPTELA-EAIARCDQKLLHISLSRPVMLLTEDRQPFRDLLTDESDIRPFHVK-VGLDWVSNFEETRWFLVLRVTKPLA-ISNKSLAAFQQPPLY-SDYFHVSIA-WSLRV-----IPFTSVKLRIGNII Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 SALLVNYSSSDDES---DNNDSRPKKRKLPV--LPLSIDDPSLHQGRIRTIPHVDGQFASHIYIALPLGREQQLLRDILREALHISLSRPIFLRVHQREDLKKALRAARRQKKFTLSFATFSELVNDEKTRTFLTMEVGAGAE-ALSPALQGIRQKEYYTNPRFHASIA-WAHELLMALNFDVEKIHVKIGREV Lenti61 A--LVEYSSSDEEA---------AAAEKLPS--LSAHLDNPALHQGRRRTTPHVEGQFAAYVYVPVVITKNSELLSRMISAAFHISLTRPTYLRAHQREEFKRAIRTARTRVKFPASLSTVSELTNDERTRTFLTLEVGAGSD-SLTPALRSIRQKEFYEQPRFHISIA-WALSLVPQLQFEAEEVCVRIGKDV Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 -MPLVDYGSSSDEDGNGKHQISNRKKVSLPP--LPSTLDNPDRHQGRIRARAHVDGSWPVHVYLEVKLSHE-DIVSTLTKTALHISLTRPIYLQELHLGHFASDIRDFKNRKRFNVNFSGVQSFSNDDQTRSFLSLRVGAGVA-EMDVIAQRYSQPKFYPDPQFHASFA-WALDSMSELDVKVKKVSWKIGQKT Mucci2 MNSLVQYDSSSDDDQDEHH----KSVPNMPK--LPSFFDSSRDHQGRVRTVPHQHDSWATYVYCKVELSHE-ALHPYL-KDVQHISLSRPVYLRKYQLTPFTRSIKALRNTKRFDASFAQVSHLTNDEKTRAFLTLEIGHGMK-HVDNVMREYHKPTFYNPPRFHASIA-WSL-------FNIDKVYIKMGNRL Mydma MSGLVSYSDSENESADKKTDVQSKKKRKIID--LKNSSPVPISIQNKVRTFEHFEGNWPTYVFTPLTINSNTYLVHTFKDLSCHISLSRTVPIRHYWMEPLYSKLKDIPQHS-FTYSFLNIKVYVNDEKTRTFIGVEINSGTD-SVDKVFKEFGLDIYYKEPSFHVSFA-WCLDSFSQLKVIASKVCMKCGNKL Neucr2 KRPLVDYDSGSESE--GSSSDGPKSTSSLPP--ISDRFDDPSLHQGRQRQVPHIPGNWPSHVYIPSSGDRE-SLVDKLQTRVLHISLSAPLTLTSKNKDAFLDDVTRSSGVSPFVVDFGGVNWYRSEESTRSFLVLRVREVLQ-RCNKTAKEYGQPPLY-GYRFHVTIA-WTHSIFDDCKFRVETVKVKIGNHV Orpsp11 L--LVDYSSSSSEDEIEKKEQKLINKKKRPP--IPNEVNKPS----RAPIDKPIEGNWPTYIYINTNFSDEMEMTSKLEKLNIHISLSRTIFLKYFQHDRFINLFNELSYIKKFYISF-NFKNYINDDKTRSFFSMNVGTG-----NK---------------------------------------------- Pench1 -MPLVQY-SDSESD--ESRSSLP--GPSLPP--LPASFDNPSLHGGRKRVIPHVEGNWPTHLYLPGKDELS-DVISQSGNVPLHISLSRPVVLRTEQRASFTEALQKDAQVSSFHVQ-DSLYWSSNYEKTRWFLVLGVQRPLK-LSNDTLARFGQPPLYASKCFHISLA-WCLRV-----VGFDSVKAKIGNIV Phybl2 MQGLVDYDSESSDE--NSEDTSPRKRQVMPP--LPDFFSKESSAQDAPSIKPFREDSWATHVFIKVDIGKE-NILRVLLDQNLHISLSRCVVLRTHQLHTFESSIRKLKDVQKFFISFANLSILTNDTGKASFLTAEVGAGLS-AVDKIVERFKHPVFYQPPRFHASLV-RANDLVEDLRTSVTKIYINMGNNI Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 A--LVSYSSS---S---EDNDEPPKKRKLPP--LASALDNPALHQGRIRTIPHVEGQFAAHIYVALHLERNSKLVDEVLERALHISLSRPTFLRAHQRDVLKRAVKTAHSSSPFVASFASFSELTNDEKTRTFLTLEVGAGSE-CLTPTLQSIRQKEFYPEPRFHASIA-WALSLVHDLNFDVDGVKTKIGKDV Polpo MDLIFQYESGDERSSSEEEEKSCSTADEIPD--LPDDLD------GKKRLFEHVDGNYPTYVYVKIPTS--DAMIEEVGSIAYHVSLSRVFTMREHHIDTFTSEMTTLKNIKEFTINFETISTFVNDGQSRLFFSANVCR-IK-KIDQVLKQFKFPVFYETPLPHLSVN-WKATIVDT-------IYWKIGKYE Pucgr2 --------------------------------------DKQSNIQ-------------------GTGENDQS---------------------------------------RSFEVYFSNFSTLVNDEGTRAFLALEVGSG-----------------------------WALALFSQKH-------VKIADTQ Punst1 ---LVDYESDSESEDARREDGKPAKKRKLTP--F---VDDPSLHQGRKRTVPFVEGQFCAYVYVPIFIPVKSKVLKAAIKDALHVSLTRPIYLRAHQREELKCAVKSAHSHRKFHASFAKFDELQNDEATRTFVVAEVGAGTS-VLSPAISALRQSTFYDQPRYHISIA-WALSLIPALNVDVEKICVRIGKQL Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 ---MVE-----------------KKKRKLPS--LDDSFDSPDLHQGRKRTTPHVEGQWAAHVY--LDLEPSARVLKKARDACLHLSLSRPLILQTNQRADLRAGVAKAGQVAGFAARYASFAVLENDEKTRRFLGIEIGQGVR-KVDDMLAAHRLPTYYAKPRFHTSLA-WSTAVLADLEVWAGELCVKIGKDV Rozal11 ------------------------------------------------MKNDKKIGLFPLIVY-PVELDQV-KIYNEIPSDFLHISLSKNEVLPHHCIEGFSDALVKEAEIAKFRVTMKRFNRYKNENGDKDFIAIDIDKGVD-IVNNVMKRYGLNLYYD-----------------------VTLSVYLD--- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---MMQQSSSRGHGGV-----------------------------QRVRQFPHVEGQWPTFACLRLHDGEEEDVLEAAMEVAVHVSLSRTFTLQLGEIDSFVSQVRQVASVPAFYAPLFRGYVMLNDDGSRAFFCVGLNQRLD-RIDECLAAFAKPAFYEARDIHVSLASWVINLLDAIQIPGDTVTVHSGNKT Schco3 SAALVDYAGSDDNSSDPSSSTSPSRPRKLPY--LAPSIDNPALHQGRIRSVPHVDGQWACHVYVPVTLKPRSDVLEDAIQRALHISLSRPIFLRAHQREDLKRAVKRARETQGFSTSFTSFSVLTNDENTRAFLTVDVGAGTS-KLTPFLRSVRQQEYYSCPKYHASIG-WTLGVVDGLNVEVGRVSVRIGKEV Schpo1 -MSLVCYESSSGEDDD-------PRMLKVPK--LQESFDSPEFHEGRIRGQKHIEGLWFVQTYLEVDLSKKVEFLNS-----LHLSISENYRINYSTKNQLVHKWEQTNNLNYRTLKFGKMCLLFNDEKTRMFLAFECKFSIS-HASDCMKEFTNRNLREDFLLHISFA-SSLHFFKTMNFIVDSLKLSIGHLI Sorma KRTLVDYESGSESD--GSPSDNPKSTSPLPA--LGDRFDDPSLHHGRQRQVPHIPGNWPSHVYIPSSGDRE-SLVDKLKAEALHISLSAPITLTSNNKDDFLDDLTKSCRVSPFVLDFGGVNWYRSEESTRSFLVLRVREVLE-KCNKIVKEYGQPPLY-GYRFHVTIA-WTHSVFDDCELPVQMVKVKIGNYV Sphar --------------ME-------T----------------------------------PVHSF----VSEEN----------LHVSLSKTVALQHHEIDAFYAALAELRSVHAFTLSLQGLRHFTNENEHRSFLALCVADELP-CVDTVMRLFIKDVYYQNPSFHASVC-WWASVADTLSFVIDTIYCKFGHTV Spipu1 PMSLVDYPSDSEDDSA-------IEKKRQRS--DSTSRTEPEKKQ-RIRQAPFVEGNWPTYVYCSFRPSVN-DLIGRINQRALHISLSRTVFLKVFQIDRFVNVLTRLTGRRRFSTGFTNITNYTNDDGSRSFLGIDVGHGVK-DVNSVIAQFRQDTFYDNPSFHASIA-WTFSVVNSMQFPIDAVTCRIGNKL Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 RP-LISYSSSSGESSSPEPEDTPPKKRKLPP--LSSQLDDPSKHQGRTRTVPHVDGQWAAYVYVPIKAGARDRLVRRTLASALHISLSRPVFLRAYQREEFKRAVRIAKSNKSFTGSFATIAALTNDEKTRSFLCLEVGAGSD-DLTPTLRSMRQKEYYAYPRFHASFA-WALNLVASLNFEVEELKVRIGKDV Tapde11 ----MAFG-------------------------------------NRIS------------------------------------------------------------ESTSIDLSFEGFAVFSNDEETRQFLVAKLSRTIRVSLDAILSQFDLPALYKEPQFHASFA-WRDWLLERLDIEIDCIKVKIGKDV Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 -MGLVDYDSSDDSIPSSTSSHSPSRKRPLPS--LPTTYDDPTLHQGRKRTRPFVEGEYSCHIYVSIPTSLRSEILITLKRLLLHISLSHPLGLRRSQIPTFLSGLSKIRSTSNISSSHGNIKVYLNGKKGRAFFALRLGAGMSPDSDTCLR-------------------WSVSCFHDTD--IVEIIERVNEAL Trire2 -MALVDY-SSSSSS--SSHSDSEGRESDLPP--LPPAFDDPALHHGRKRLTPHVVGNWPSHVYVPLADQHE-RLVCSVNEAILHISLSRPLSLSTSNKDRFLDQISSASGVSQFSVS-RRLLWYNSPDSNRTFLILQVASSLN-ACNAVAQRFDQPILYQ--AFHISIG-WALEVFRDGEIPVPGVKVKIGNVV Umbra1 MASLVDYSSESESETSKRS----RSDSSLPP--LPAAFDNPEKYQGRIRTVPHTEGQWPTHVYIEVPCSKE-DITAHI----CHISLSKCLYLKEFQHETFVAQIKRIKLIKPFSLSFAAIAPLTNEVNTRSFCSLEVGYGMA-VIDTVAERHRQPKFYQPPRFHASIA-WSLMPMEKEDFYVTRLLIKIGKKV Ustma22 LAGLSQYTSDSDPEDASAHSLTSRLKRKLPPL------DSSGAASGRI-TTNGLRGDWLCYCFVEVVVGPS-NCIEQSDDYLLHISLTRPFTVRSYERDEYVKIATAKENISSFPFTFSRIAYLSNDDASRHFMVLEVGSGSTALSTELRRAFRAKVYYEEARFHASIA-CVMTIIDKIEVWATRIGIQLGNRI Walse1 --MLVDYASSDSD----------KEEIYVPK--LPTIFDNPSEHQGRVRSQPFREGVYYTHVHLSIPLDYK-KLLEEIYNDFFYISLSRPLGLRNFQIKPFNKAIESTNNHKAITVSFSDIDVLFNDNKTRAFIVLPIVAGLRDIDNGPVRENKQEPYYDPAVLHTSIA-WMLDDLRETTFESTKVNVKVSKQV Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3334.fasta_al_trimmed; alignment length = 98] Allma1 VLNAQVSIRAQCC-RRWFDCPECHAEVS-DHPLKRVTEMVFGCKKCKKVFRKD-MADY-DEQDEFCPYCDNQYVIEAVEPVGFEADDDANAV--IDPR Ashgo11 -------------------------------------------------------------------------------------------------- Aspfu1 -------------------------------------------------------------------------------------------------- Aurde31 ILNAQVSIRAPCC-KQWFDCPECHAERE-DHKLQRTTEMVFVCKKCKKAFRKD-MTVY-EESDEYCPHCDNHYIIEAKTAVGMAATDDPRMM--QDER Batde5 ILNAQVSIRAPCC-KKWFDCPECHEESS-DHKLRKIVEMVFACKKCKKTFRKD-LAEF-DDQDEYCPHCDNHYIVDAKMP------------------ Botbo1 ILNAQVSIRAPCC-KKWFDCPECHAEVS-SHNLAKTLEMVFMCKKCRKAFRKD-MTVY-EDSDEYCPHCDNHYVVDAKSPLGVEGEDDARMI--KDDR Botci1 ILNAQVSIRSPCC-RKWFDCAECHQETE-SHPLKKTTEMTFACKKCKKAFRKDFADET-DDGDEYCPHCDNHYVIDAIEPLKFEGEDDSRMI--KDDR Caeel -------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------- Capow VLNAQVSVRAACC-KKWFDCPECHAGSE-QHPLRKTVELVFACKKCKKVFRKN-STNFDEETDSYCPYCDNKYILPASSKVTL----DVSAL--RDMR Catan2 ILNAQVSIRAQCC-RRWFDCPQCHQEVS-DHELLRTMEMIFACKKCKKVFRKD-MENY-EEQDEFCPHCDNQYVIEAVEPVGFETEDDASLI--RDHR Cioin -------------------------------------------------------------------------------------------------- CocheC53 ILNAQVSIRSPCC-KKWFDCAQCHEEQS-NHPLMQTFDMTFICKKCKKAFRKD-AREF-EDADEYCPHCDNHFVLEAKTPLQVEGEDDSRML--KDDR Coere1 ILNAQVAIRAPCC-KKWFDCPQCHADKA-DHPLQKTEEMAFLCKKCKKAFRKD-MSDY-EDEDEYCPHCDNHYVVEAKTPLGVEGEDDSRLL--KDDR Conco1 IRNAQVSIRSQCC-RQWFDCSQCHSEQT-DHKLRKTFELVFACKACKKVFRKD-SRDL-DETDEYCPHCDNHYVVPAELPINNESEDDPRMI--KDTV Conpu1 ILNAQVSIRAPCC-KQWFDCAECHAEAE-DHRLAKTNEMAFICKKCKKAFRKD-MTAY-EESDEFCPHCDNHYVIDAKTPLGVEGEDDARML--KDDR Copci ILNAQVSIRAPCC-KQWFDCAECHAETQ-DHKLKKTNEMAFICKKCKKAFRKD-MTNY-EESDEYCPHCDNHYVIEAKTPLGVEGEDDARYV--FDTG Croqu1 ILNAQVSIRSPCC-QKWFDCAECHEDQKLGHRLVKTNELVMACKACKKVFRK-AIDEF-EDADEYCPHCDNHYVIEAKTPLGVEGEDDGRGLSNRDER CryneH991 ------------------------------------MEMAFLCKKCKKAFRKD-MTEY-EEADEYCPHCDNQYVIEAKEPVGVEGEDDNRML--KDDR Crypa2 ILNAQVSIRSPCC-KKWFDCVECHQEQE-THPLLQRFEMIFACKKCKKCFRKD-AQEF-EEADEYCPHCDNHFVLEALTPLRVEGEDDNRML--KDDR Debha1 -------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------- Dicdi ILNTQVSIRAKCC-NKWFDCADCHREVS-DHDIYKSDEMIFACKKCKKVFRKT-ISTF-EEADEYCPHCDNHYYLEAVKPIELDGDEETLMLDPRQKR Dmel -------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------- Falba ILNAQVSIRAPCCKKKWFDCAECHAAVS-NHELHRSTEMVFACKKCRKVFRKD-LSEY-EEADEFCPHCDNQYIIPAKTPIGLEGD-DPRLV--RDDR Fomme1 ILNAQVSIRAPCC-RQWYDCAECHAEAQ-THKLVKTTEMVFMCKNCRKAFRKN-ITEY-EESDEFCPHCDNHYVIEAKMPLAVEMDDDPRML--KDDR Fusgr1 ILNAQVAVRSPCC-RKWFDCVECHGEQE-DHPLKENYEMIFACKKCRKCFRKD-VTEF-EEADEFCPHCDNHFVIDAKTPLSVESEDDNKML--RDDR Galma1 ILNAQVSIRAPCC-KLWFDCPECHAETQ-NHTLAKTTEMAFICKKCKKAFRKD-MSAY-EESDEYCPHCDNHYVLDAKTPVGVEGEDDARML--KDER Ganpr1 --------------------------------------MVFACKKCKKVFRKD-MSNY-DDSDEYCPHCDNHYVIEAKAPIGVEGEDDSRLI--KDDR Gloin1 ILNAQVSIRAQCC-QRWFDCADCHAEVS-DHQLSKTLEMVFACKKCKKCFRKD-MENF-DETDEYCPHCDNHYVLDAKTPIGVEGEDDNRMI--KDER Hisca1 ILNAQVSIRSPCC-RRWFDCAQCHQEQE-NHELLQSFDMTFACKKCKKCFRKD-AREF-EESDEYCPHCDNHFVLDAVTPLKIEGEDDSRML--KDER Klula1 -------------------------------------------------------------------------------------------------- Lacbi2 ILNAQVSIRAPCC-KQWYDCAECHAEAQ-THPLGKTTEMAFICKKCKKAFRKD-MSVY-EESDEYCPHCDNHYVLEAKTPVGVEGEDDARML--KDDR Lenti61 ILNAQVAIRAPCC-KQWYDCAECHAEAQ-SHPLAKTTQMTFLCKKCKKAFRKD-MTEY-EESDEYCPHCDNHYVIDAKTPLGVEGDDNSRML--KDER Malgl1 LFNA---IRAPCC-RKFFDCPECHAETQ-THPLAKTTELAFLCKKCRRAFRKD-MAVY-EQADEYCPHCDNHYVIEAKTPLSVEGDDDPSII--RDDR Mellp23 ILNAQVSIRAPCC-QRWYDCPQCHDDEKLGHRLAKTTELSLACKSCKKVFRK-PIEDF-EDADEYCPHCDNHYVIEAKTPIGVEGGDDGRGLSNRDER Mnele -------------------------------------------------------------------------------------------------- Monbr ILNAQVAVRAPCC-KKWYDCPECHDEFE-SHELKKSYEMVFACKKCKKVFRKD-SREF-EESDEFCPHCDNHFMIPAKTPIGIEGEDDHRML--RDER Morel2 ILNVQASIRAPCC-KQWFDCAECHGEVS-DHPLRKTTEMVFGCKKCKKVFRKD-MDHF-EEEDEYCPHCDNKYIVEAKTPIAVEGHDGERFE--KDMR Mucci2 ILNAQVAIRAPCC-KKWFDCAECHAAVS-DHNLRKTNEMVFACKKCKKVFRKD-MTDY-EEEDEFCPHCDNQYVVDALMPIGIETEDDNRVV--KDDR Mydma -------------------------------------------------------------------------------------------------- Neucr2 VLNAQVSIRSPCC-RKWFDCPECHAESE-SHPLKKTLEMTFACKKCKKCFRKD-ATEF-EDSDEYCPHCDNHYIIEAVTPLRVEGEDDARML--KDER Orpsp11 -------------------------------------------------------------------------------------------------- Pench1 ILNAQVAIRSHCC-RKWFDCAECHQESE-SHMLQKSAEMIFACKKCKKCFRKD-AAEF-DETDEYCPHCDNHFVIDAIEPLHVEGEDDNRML--KDER Phybl2 VLNAQVSIRAQCC-KKWYDCAECHAEHS-DHALRKTDEMVFGCKKCKKVFRKD-MTDY-EEEDEFCPHCDNQYVIEALTPLGIETGDDSRVV--KDQR Picst3 -------------------------------------------------------------------------------------------------- Plicr1 ILNAQVSIRAPCC-KQWYDCAECHAEAQ-THRLAKTTEMAFMCKKCKKAFRKD-MTAY-EESDEYCPHCDNHYVIDAKTPIGVEGEDNARMI--KDER Polpo ILNAQVSIRASCC-KRWFDCPECHQEAS-DHPLRRTEEIVLACKKCKKVFRKNTSAEM-DESDEYCPHCDNHYVLDAKTKVEFQGSKDKRMKL----R Pucgr2 ILNAQVTIRAQCC-RKWFDCAECHAEQQPDHKLFKSSEMVMMCKKCKKAFRKDVVDEF-EESDEYCPHCDNHYIIEAKTAIGIEGEDDPRGLVTRDER Punst1 ILNAQVSIRAPCC-KQWYDCAECHAEAQ-DHPLRKTTEMTFICKKCKKAFRKD-IAEY-DESDEYCPHCDNHYVLEAKTPIGVEGEDDSRMI--KDER Rhior3 ILNAQVSIRAPCC-KKWFDCAECHAAVS-DHQLRKTNEMVFACKKCKKAFRKD-MTDY-EEEDEFCPHCDNHYVLEAVTPLGIETEDDNRVI--KDDR Rhoto1 ILNAQASVRAPCC-KKWFDCPECHAEVS-DHPLAKTTEMAFMCKKCRKAFRKD-MSKY-EEADEYCPHCDNHYVIEAKTPLGVESEDDNRAI--KDER Rozal11 -------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------- Salro ILNAQVAIRAPCC-KKWYDCPECHEEKA-DHPLKKSYEMVFACKKCKKVFRKD-TREY-EEADEYCPHCDNHYVIPAKTPIEVEGEQDHRMI--RDER Schco3 ILNAQVSIRAPCC-RQWFDCAECHAETQ-DHRLAKTNEMTFLCKKCKKAFRKD-MSVY-EESDEYCPHCDNHYVIEAKTAVGVEGEDDNRML--RDER Schpo1 VLNAQVSIRTACC-RRWIDCIECHNEIA-DHPLLKTSELTLICKKCRKAFRIQ-FDQTMDESDEYCPNCDNHFVIDA---TKVEKPKDLRML-NQEEK Sorma --------------------------------------MTFACKKCKKCFRKD-ATEF-EDADEYCPHCDNHYILEAVTPLRVEGEDDARML--KDDR Sphar -------------------------------------------------------------------------------------------------- Spipu1 ILNAQVSIRAPCC-QKWYDCPECHQEVS-DHNLRKTVEMVMACKKCKKVFRKD-MSNY-EEEDEYCPNCDNHYVIEAKTPIGIEGD-DPRLV--KDFR Sporo1 ILNAQASIRAPCC-KKWFDCAECHDEKEPDHALVRTTEMAFLCKKCKKAFRKD-MTVW-DEADEFCPHCDNHFIIEAKTPVGVESEDDNR-------- Stehi1 VLNAQVSIRAPCC-KQWYDCPECHAEAQ-SHPLAKATEMVFICKKCKKAFRKD-MAEY-DESDEYCPHCDNHYVIDAKTPIGVEGDDDARML--KDER Tapde11 -------------------------------------------------------------------------------------------------- Thetr -------------------------------------------------------------------------------------------------- Treme1 ILNAQVSIRAPCC-KKFFDCPECHAETQ-DHPLAKTIEMAFICKKCKKAFRKD-MTHY-EEADEYCPHCDNHYVVEAKEPIGVEGEDDARMI--KDER Trire2 ILNAQVAIRSPCC-RKWFDCAECHAEQE-SHPLLQSFEMTFACKKCKKAFRKD-AQEF-DESDEYCPHCDNHFVIEAKTPLTIEGEDNNKLL--KDER Umbra1 ILNAQVAIRAPCC-RKWFDCAECHAEVS-DHSLAKASEMAFACKKCKKTFRKD-LSDF-EDEDEFCPHCDNHFVLEAVEPLGVEGEDDSRMI--KDDR Ustma22 ILNAQVSIRAPCC-QKFFDCPECHAESQ-DHMLRKTIEMAFICKKCRKAFRKD-LTQY-EESDEFCPHCDNHYVIDAKTPLSVEGEDDNRML--RDDR Walse1 VLNAQAAIRSPCC-RKWFDCPECHEEKE-DHPLAKSLELAFMCKKCKRAFRKD-MTVF-EESDEFCPHCDNHFVIDAKTPLMVEGEDDNRMI--KDER Zygro1 -------------------------------------------------------------------------------------------------- [Cluster3344.fasta_al_trimmed; alignment length = 188] Allma1 FDGVALRGVVFGDAVAIDARGDVFQWGRTLTGLDIVQVHVARDLFALSRSG-TLYMIADVRAGDDHVVVRTKKGEVYSAAVA-AGALGVVPQLHEIAAGAAHALARTSDGRVFAWGTNTHGLPTEIIAAAGQMSAFITGTLGHGQYIHTVKEITLALGHAAAVLDVLFWGAGARR-KHLATPVPGHPL Ashgo11 FEGERLRDVALAENLAIDRRGDLYAWTLLLPGQDLCQVQISNGAYGLRGNG-DLLVVVKFATGKRHLVAVTDRGHVYTCASC--GQFGEVELLNHIACGNYHTLAIDSKGELYAFGANTYGFPRRIIHCCGETSFVSVGQLGNGRFKHKLKAVTWACGHVLCSLDVLAWGYNGRG-VKWAQPQNVPAL Aspfu1 FEGQVLRDLKISEGAAITENGDLVQWGKTLTGKDLRSLCMSSDILALASNG-NVYSVTAISGGLQHALLLTNSGRVFSVAPS-FGQLGEVKTLSEVATGDYHSLALTKDGNVYAFGDNSFGTPTLVIAAGGANSFFTVGALGNGRWTHKVKALNISVGHASAIMDALFWGGNGKR-NNLSKPSHINA- Aurde31 LALPPLRDLALHAGALVDARGDVYQWGPTLTGKDITSVALSGRLYALSKSG-RVFVFTSISAGSAHLLALTSAGRVFAHPNA-YGQLGDVPALSQVVAGDRSSFVRTQEGRVLAWGANEYGVPSEVIVAGGDLTFFVVGALGNGVFSSRIRAVALSVSHVLLTLDLLSWGLNGAR-KNIAVPAPLEDG Batde5 FKGRALRDLAFGDAAAIDEHGNLLQWGLTFTQHNLVKVTCASQTYALSR-------ITSISCGSSHLIAVSNTGRAYSFANK-CGQLGRISGLSKVAAGRSHSIIGTTDGRAFGFGQNRFGSPVQIIAAGGDTTLFVVGQLGTGNFNHLIKPLKVCVGHCCVVMDVLVWGMNSKK-GSLASPGYMLPI Botbo1 LSGVALRDLAFHEAACIDARGDVYQWGLTLRGQDITHLAVTHSVFALSRAG-QVFVIVSISAGRDHLLALTSSGRTLAHPNS-HGQLGEIPSLRQAVAGDRSSFVRTEDGKVLGWGANEYGVPTEVITAGGDVAFFTIGALGSGQYTQKVKTVTISVSHVLFAFDLLSWGANGKK-TNVATPTYVTDW Botci1 FDGKLIRDIKLDRAAAITENGDLLQWGATLKGKDLVKLSISKDIIALSSKG-TVYSVSDISSGLEHCLLLTSKGRVFSAAPT-KGQLGWLSTLQKIATGDYHSLAVDTQGRVFSFGDNSVGAPSLVVFAGGVNTFFTVGTLGNGRWTHKMKALRLSIGHASAVMDVLWWGGNGKR-NNVSQPIYIQPL Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 FNNMYLKDAYIEKLIAITDKGKVYEWDPINLPFNIERVTPTKDFYFLTNKG-EIVYITKISSGDYHLLLLNKSGKIFVVNIN-RGQYGDLTLLNYISSGKYFNIVSDDNGNIWTWGDNSCGVPKIVLCTGDDSSYALIGQLGGGRYMQIVKSLDISVGHLFITLDVYALGENGKR-NKSCKPMKIPKL Cangl AFNKELKDLIILDCLGVDQAGNLV---VILRGQKLEQLKLSGKIYALNKDG-KILIISQFDVGKDHLVLISNHGKAYTCSES-FGQFGEIEMLNQVACGDYHTLARDSLGNLYSFGWNRFGYPKIILNCSAETSYVTMGELGNGIYKNRIKFEQWYTGHVICKLRLVAWGRNGKK-IKQSKPTNVPAV Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 FNGMRFRHVALAEAAAIDANGDLYQWGKTLVGHDLVRVSLSKDLFALSRTG-KLLVIVDVASGSDHVLALTKSGAVYSAAVH-YGSIGPLPALSQIAVGSAHSLALTADGRAYAWGSNAFGLPAQIVAAAGDMSALVTGTLGNGQFAHHVRALALVLAHGACVLSVYFWGTGGTR-SHQAKPVLAGPL Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 FDGKLLRDIKLDKGAAIDEKGDLLQWGKTLTGRNLKSLAISRDIIGLSNNG-SVYSVTDICSGLEHALMLTSSGRVFSFAPS-KGQLGEITTLKKIATGDYHSLVCDSEGRAFTFGDNTAGAPSLLVFAGGNTSFLAIGQLGVGRWVHKVPAFTISVGHAAAILDILFWGNNGKR-SNLATPAYIQPL Coere1 LEGKLICSVAFSKAVAVDYEGCVYQWGCTLRDASIGEVAASDDVVLLDKKS-RVRLVTHISAGKSHIAATTSAGHVYTCANS-RYQLG------AAACGDCHTILLTTEGDVLGCGANDFGSLILLIAAGATTSFAQVGQLGNGTLSHIVPALSLAAGHVVAVCDVVVWGRNGRK-HRFTQPEYPPPL Conco1 FDNCALRDLKLGKAAAVDVNGDVYQWGKTLKGWNIVKVELTDDIICLTQNG-HLFLIVELESGNHHIAIITSNGRLLTLATQ-FGQLGEPEFLDKLAIGSNHTIVASSSHRLFGFGMNDLGEPVELLHLGGDTSFINAGQLGNGQFVHQVTQLQISAGHAFFVLSVYALGRNDKR-SNASSPITLPPI Conpu1 LQKVALRDLALHEGACVDARGDVYQWGMTLSGKNIASLQVTESVFALSLSG-KIYVFVSISAGQDHVLALTSSGRTFSYANS-HGQLGEIQSLQQVAAGSRSSFVLTDSGRALGFGANEYGVPTEIIAAGGNLTCFVAGGLGNNVFTTRARNVGISISHILLSLDLVVWGLNGRK-SSLAVPTMIEKP Copci LDGVALRDFQLHEGACVDARGDVYQWGLTLKGKNITQLQLTEDVYALSASG-HIYVFTSLAAGNNHLLALTSKGRTFAHPNR-HGQLGELPVLKQITAGSRSSFVRTTTGRVLGWGANEFGVPTEVVAAGGDLTGFIVGGLGNNTFSTRVKAVDISISHVLLALDVLVWGRNGKK-SSISSPTRLEVP Croqu1 FREEALRDLVLHEAVAVDARGDLYLWGKTLGNCDIKQICCTRNVYALARSG-KIYVFTSISAGDHHLLAITSKGRTFASPNN-HGQLGEVPALRQAVCGSRHSLVLTSTGDVLAFGANEFGAPTEVLAAGGDTSYLIVGGAGNGQWTHKVKTINISVGHVAAVLDVFLWGQNQKR-ANVAIPQHISPL CryneH991 LGGTPLRDLVIAEAAALDANGDCWLWGKGLVGKDLKTLVPGQSVFALSRSG-KLYVWKQVAVGSHHLLALTTKGRLFSMPND-FRQLGPIPSLSHVATASHTSYAITSTSRLLSWGANSLGVPIEIVKAGGDTAFFTVGALGTGSYSSKVKVIRLSVSHAFAVLDVFAWGANGKR-TSIPIPTYIPAL Crypa2 FDGMLLRDLKLDQGVAVTEQGDLVQWGYTLKGMDIVKLAISRDILALSKGG-SVYSIVDIQSGQDHTLLLTSSGRVFSAAPS-KGQLGEISTLKKIATGDYHSLVLDDEGRVFVFGDNSVGVPSLLIAAGGSNSFFTVGGLGTGRWTHKIKALRVSVGHTAAVMDIVWWGGNGKR-TNSNAPIYISPL Debha1 FDGMLIKDVQIFQLAVINEKGEFYQYHLTKLGSKVTKCQISNDVYLLTKNG-EVIYIKDIAAGQSHILMLSSEGRLFVANMN-YGQFGELKLLNSIAAGKFHNIVVDTEGNVWSWGKNTFGVPKKVVYAADESSYVKLGQLGSSRFMHIVKSLDVSIGHGFVTLDVLTFGDNGKV-AKSSKPVRLPKL Dekbr2 FDHKYARYVALGSGVLIDDKGDLFQWGASLKGQNLVKACISHGIYALSKNG-QVIYIKDIAAGKYHLVLLSNDGKVYTSASS-WGQFGEVTLLNKIAAGDYFTMCLDSTGRVWEFGKNTYGFPSPVIAAGGQTAFATCGELGTGRYVHKIKVLNWSVGHVVAMLDVYVWGDNGKK-SRSAVPIAPPSL Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba FGTPALRDLSVHLGAAVNARGDVYQWGLTLRGLDAVQVETAGQSVALTRQG-SIVVFSKISVGDHHLLAVSTCGRLFSCPNA-FGQLGPVIGLPDVATGAGHSLAACDSGLVYAFGDNRMQEPTLCLAAGGDTSAFVVGQLGSGSFLHTVRNLTLSVSHCAAILDAFLWGDNGLR-AMVGVPWQPSER Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 FNDQILRDLKLTSGAAVTEKGDLVQWGSTLTGKDIIKIDVSLDIIALSRKG-NVYSVKDISTGQEHCLMLTSKGRVFSAAPS-KGQMGEVTTLQQIAAGDYHSAVLDKTGRIFGFGDNSYGTPVMVIAAGGNNTFFTVGTLGTGRWSHKVKGLSLSVGHCSAIMDVVFWGGNGRR-TNLNAPAYIAAL Galma1 LNGVALRDLQLHQAACVDAKGDVYQWGLTLRGKNIVELQLTDDIYALSASG-KVYTFTSIKAGKNHLLALTSKGRVFSHPNY-YGQLGEIPALREIAAGERTSFIRTSAGKVLGWGANEYGVPTEVITAGGDLTAFTVGGLGNNLYTTRVKAIEISISHVLLALDLMVWGRNGKK-SSMATPTALQTA Ganpr1 FRGWVLRDLRLESGAAVDVEGNVWEWGETLRGKNVRQVALTQKTYAVGRDG-RVWEITTINAGSHHLLALSNRGRCFTLPNV-NGQLGPVTSLPQISTGTDHNLVRTEDGRAFGWGGNGFGTPRELIAAGEGVSFLVGGQLGTGVYPHKVRALDISCGHCAATLDVLIWGAGKRR-TNLPVPTHIDGF Gloin1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 FDGMVLRDVKLDQGAAITENGDLIQWGKTLKGKNLVSLCISADIIALSSGG-NVYSVTAISSGLEHLLLLTTSGRVFSAAPS-RGQLGEVRELRNIAAGDYHSLALDKTGRVFVFGDNSSGTPQILIAAGGANSFFIVGVLGTGKWTHKIKALHISVGHAAAVLDVFWWGGNGKR-NNIASPTHIHP- Klula1 FDGMKLRDVCLTDNLAVDKDGNLFEWDLLLKDQNLVQIKVSNDAYGLNKKG-EVLVVIQFDVGSNHLVLLSNKGKAYTCASK--GQFGEIELLNKIACGDYHTLACDSVGELYSFGLNTYGFPKKVINCSGNTSFVSIGQLGNGHFKHRMKVIDWYCGHAFVRLEIMCWGYNGKK-IKWDKPAYIPRL Lacbi2 LEGVALRDLALHEGACVDARGDVYQWGRTLRGKNIVNLQLTEALFALSASG-KIYVFVAIAAGKNHLLAVTSKGRTYGLPNE-YGQLGEIPVLQQVAAGGRSSFARTTDGRVLGWGANEYGVPTEVVTAGGDLTAFTMGGLGNNTYSNRVKAVAISISHILVALDLMTWGKNGKK-ASVPVPMTLETP Lenti61 FKNVALRDLALHEAACIDARGDVYQWGLTLKGKNITQLQVTRSVFALSASG-RVYVFVQISAGSDHLLALTSDGRTFAHPNS-HGQLGEVPALKRIAAGGRSSFVKTPDGKVLGWGANEYGVPTEVMFAGGDLTIFEVGGLGNAQYSNRAKNVTVSVSHVLLTLDVMAWGANGKR-GSQSTPTLIETM Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 FQEEALRDLVLHEAVAVDSRGDLYQWGNILSNHDIKQIACTSYIYALSKSG-KVYIFTSISAGDHHLLAITSKGRTFASANS-HGQLGEIPALRQIACGSSHSLVRTATGDVLAYGSNLYGAPTEVLAAAGDTSYLVTGGVGNGQWNHKVKTI---------------WGHNRKR-ANLSIPQHISPL Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 FQGKILRDLKLGDAAAVDEDGTVYQWGATLTKRDIAQVTLCDTLYGLSRDGSRIYVVLSMSSGKSHMVMVTSHGRVFG--LS-ISLIG------EVACGEVHTLARDDQGRGWAWGINGFGNPTLIVAAGGQSSYFVLGQLGDGSYTHTITPLDLAIGHGFAVLDVLSWGQNGKR-TNKTEPVHALPL Mucci2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 FDDQVLRDLKLDSGAAIDEKGNLVQWGVTLKGKDLVKLDLSRDIIGLASNG-EVYSIVDVRSGLEHCLMLTSNGRVFSAAPS-KGQLGEVTGLSEIAAGDYHSLALDTEGRVYAFGDNSFGSPRPVIAAGGPNSFFTVGTLGNGKWTHKVKALRMSVGHACAVMDVLWWGGNGKR-NNVNTPSYIVPL Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 FDGQLLADVKIAKLVVVNEKGQVFQSCLCKLPFKAALCQISSKVYVLSSKG-EVAYIRQISTGKSHLLLLGESGKLYVASKN-YGQYGELTNLNSIAAGSYHSIASDSHNNIWTWGRNSYGIPKRVVDAGSETSYIQLGQLGGNRYLHIIKTLDISIGHAFVTLDVMVFGDNGKA-VKSSKPVQLPKL Plicr1 SENVALRDLALHEAACVDARGDIYQWGLTLRGKNIVQIQLTESVLALSASG-RVYVFVSISAGSDHMLALTSSGSTYAYPNS-HGQLGEIQALKQIATGGRSSFVKTDTGRVLGWGANEYGVPTEVICAGGDLTSFTVGGLGNNQFTNRVKNIAISISHVLLTLDLIGWGANGRK-SSVPSPANLALP Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 LNDVALRDLALGVAVCVDARGDVYQWGATLKGKNITSIQLTPNVYALSSSG-AIYVFTSISAGTDHLLALTSSGRTFAHPNS-NGQLGEIPALRQVVAGGRHSFIRTDGGRVLGWGANEYGRPTEVVNAGADLSMFTVGGLGSGLFSNRVKNIAISIAHVFCSLDLLSWGLNGKK-NTVPVPTQMHLP Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 LSNLILRDLALSAGVAVDSNGDVLQWGKTLTGKNLVKVVPTEAVFGLSKKG-EVWVFTSLSAGASHLLALTSRGRSFALPNT-HGQLGEIPSLRQLEAGKRHSLARLMEGRVLGWGMNSYGAPTEILAAGGNVSYFVVGGLGNGMWAHRVKTVDVQAGHVAVVLDVFVWGYNGKR-SNLPTPQHLSPL Rozal11 INGTV-NDITLAEAAAIDSNGDVYQWGCTMKNMKAKQLASNSKVFALAED---------ISAGEHHIVALTSKGRVFTGANY-FGQLGLISAKKDISCGDFHTMALDSEGRVFGFGSNHHLSPE--IAAGGLNSMVVVGQLGNKSWQQSVADVQISCGHMACVLQLYIWGYNGKR-RNFNSPTSVLLC Sacce1 LDGRKFRDILLAPNFAIDEKGDLISWDTILPDQDLTSMKYSSHLYALNKKG-EILVVVQFDAGSHHLVLLSNLGKAYCCASK--GQFGEIELLNKIACGSYHTLAIDKTGEIYAFGWNRFGFPRSVIHCDDETSFVTIGELGNNTFKNKIKSDNWSCGCVFTETEVIAWGNNGKKTMKCAKPMNIPEV Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LNGVALRDLALHEGACVDAKGDVYQWGATLRGKNIVQLQLTESLFALSSSG-KVYVFTSIAAGDDHLLALTSQGRTFAHPNT-CGQLGEVPALRQIAAGKRSSFARTKDGRVLAWGANEAGVPTEVVAAGGNLTCFTVGGLGGNNYSTRARNVDVAVSHVLLTLDLVVWGRNGRM-KSLPAPTTLFTP Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma FDDQILRDLKLDRGAAIDEKGNLVQWGVTLKGKDLVKLAMSRDIIGLASNG-EVYSIVDVRSGLEHCLMLTSKGRVFSAAPS-KGQLGEVTGLSEIATGDFHSLALDTEGHIFTFGDNSFGSPRPLIAAGGLNSFFTVGSLGTGKWTHKVKALRLSVGHACAVMDVLWWGGNGKR-NNVNLPTYIAPL Sphar FDRRGVQSITFGQAAAVTKKGDVYAWGLVVSGGGVIDMACGGDLYCLASGG-HVYKIVQLTSGKGHLMALTNKGQLFGMVNS-LGQLGKVDLAEEVACGSNHTLALTEKNDILTFGHNNLLLPTRIIAAGGDCSAVVLGTLGNSQYRHSVKTVDLCIGSVCVTLDTYAWGANSTI-VNRSKPVLVLSK Spipu1 FAGKVFRDLVLGDAAAIDLDGNLWQWHVTLKGQDLVQAACTNNVYALSRSG-EVFCITSLASGAHHLVAITSRGKVLTIPNQ-YGQLGLVSKLDRAACGENHTLVRTKDGRVFAFGANGFGVPREVIAAGGNTSFFVVGQLGNGSYSHRIKTLAIAVSHCAAVLDVLVWGCNGKK-SNSAVPIYPKAI Sporo1 LASLVLRDLKLSRGVAIDANGDALQWGRTLTGKDLVRVEATEEVFGIDRKG-QVWVFISLSSGQSHLLALTSAGRSFALPNN-FGQLGEIPSLRELVAGRNHSLARLAEGRVLGFGAGAYGTPTEIIAAGGNLSYFVVGGLGNGLWAHRVKTVDVQAGHVAVVLDVFTFGQNGKR-ASLATPQHLPPL Stehi1 LENVALRDLALHEAACVDARGDIYQWGLTLSGKNITQIKLTDSVFALSSSG-KVYVFVSIAAGRDHLLALTSSGRTFAHPNS-HGQLGEVPSLKQIAAGARSSYAKTDSGRVLGWGANEYGIPTEVLNAGGNLAFFTVGGLGNAMYSNRTKNVSLSISHVLLTLDLFVWGTNGKR-TSSAVPVNLTRG Tapde11 FDGMALRDLKMNEGVAVLDTGDVYQWGVTLRGKNIKKVELGAEIYCLSQSG-EVFVIVDIASGLEHVVLMSQRGSVLSASNA-RGQLGPVTGFRAIAAGDQHSIVLDEDGEVFTFGANAHGNPTVVIAGGGKNTFMVVGQLGNNTWNHRVKVISLSVGHVICCLDVFAWGQNGKR-NNRSMPEYIAPM Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LGATPLRDLIIAEGACVDARGDCWMWGRSL-----------QGLYCLSTNG-NLYVWENLSAGTHHLLAVTNKGRTFSLPNS-HRQLGEIPSLTQVVASDRTSFVRTTGGRVLGFGANELGTPVEIVYAGGQTTFFVVGALGNGLWSSRVKTVSISVSHAVAVLDVMVWGGNGKR-SSLAIPQHLPPL Trire2 FDNQLLRDLKLTQGAAITEKGDLVQWGTTLKGKDLSKIEVSEDIIALSRGG-SVYAVTDISSGLEHCLMLTSGGRVFSSAPT-KGQMGEISLLKKIATGDYHSVVLDKLGRVFTFGDNTYGTPTILIAAGGLNTFFVCGSLGTGKWTHKVKALDLSIGHSAAVMDVVFWGGNGKR-NNLNTPSYIGPL Umbra1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 FDGVALRDINLQEGVAVDANGDIYQWGKTLTGKKIVKVEATEEVYALSKDG-HVYVAVDIVAGNHHLLTISNKGRTFATPNA-FGQLGEIPALRQIAAGSEHSLARTYDGRVLSWGRHTHGVPTEVIAAGADNSFFMTGTIGNAMWSQRVKTVSISIGHAALVLDVMVWGANSKR-SNLAVPQHLKPL Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 FDHKVLRDVCLSDNLAIDERGDLLKWSTILPDQNLVKVKLSNNAYALNKKG-EILVIIQFDTGKHHLALVSNKGNAYSCASHSYGQFGEIELLNQVACGDYHTLARDAEGKLFGFGINKNGFPKIIINCSTQTSFVTLGELGNGNYKNPIKSIEWSCGHIWCKLQVLVWGFNGKR-IKVNRPQPIPGL [Cluster3354.fasta_al_trimmed; alignment length = 314] Allma1 SLEELLRAQPSKATISSVILTLDD-VAALNAAALVVIYAALLIPRVAALVRAADADTLRRVPDQLAAAIVVHPLVNLARKFA--LITAV--HVYALHACLLSSTDKTTTQPINIKDVLLYHYLGGMVYTALKRYTEANMIAPG-RIQVESYKKWALVSLLATGRVPPKTDSDMFANVILRVYKDLATAFDTFQAIMDAATLRADGNYGLARQAL--DALARHKVQALTTTFLTLAVADLA--VLADP-DVERMVAGMIADKQVRAVIAAMVQFL-DVAARIEKVVKAAAAVGGSFGVSERDMAMQAALLNSY-- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 SLDDVIAYATGSEVILASAASQDP-LTVLHTLAYLYILSARL-AVVNNFCKVADAGQLRHAPERILKAAAVAPLRSLVLRYPL-TLTSV--HPIFVHACVKSNAPITEIDDLTYHTSLNYHYAGGLCLAALKRYREAVVSSPA-QLQLDALNKLALIQLIVYGKTPPKYTHAILTRIFKSPYSALAKAYPG--ALADKKTWVGDQAAGLVRQAL--ARAPRWALRKLTETYVTLGLGEIGRAVGIEA-EVRAVVLSMIEAGEIHAQIEGTVTFL-DTKEDIEGLLEDAQVHAQLLQEFDRELERSRDFLQKAVR Batde5 ---------------MAVASS--------RLLAFAYKLALE-----------FNPLQLRIASHAISQCAAIRIFSLLCTN-----LTPL--HVLLLKHCLLSKVEITDMAPIRIQDFMLYHYYGGLIHIGNKHFTCACLGVPS-DIQIEAYKRFILVSLLANGALLPKTVSPVVARVCKLQYAEFATAYSSATTKASQSKFETDKTNGLVHQCL--ADLVRRKIRKLTDTYLTLSLGDITRAVGLNL-EAEAHVVRMIDDRQILATIGGMVSFH-DTTATLEDQIATLMARDTDAQILDRKIGLSQNYLQKTIQ Botbo1 -----------GEAVLSGGLEEDP-LEILNTLGVLFMMSSRLPQLIANFCNVFEPEAARLAPERILR--AIPLLLTLLTRYAP-NLTTI--HPVFLEACVSSRVPITKIDDLHYNDNLQYHYYGGVVFAALKKYKEAVVSSPA-QLQLEAYKKLVLIQLISHGKLVPKYTHALISRALKSPYVILTKAYPALTALLEKQAFAADGNTGLATQAI--QRSPRWILKKLTETYLTLSLSEISQVIGISA-EVRALVLSMIEMREIHASLTGTLTFL-DNAESVDKLLRDAQELGRSLAELDRELGIGREFLSKALK Botci1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow -IEQALAIIQGRQEQQQQQQSAEPSLLLVHTLGFIWLLRVKFIPLLHAVLSRGDEAQLQLAGYLVALYATIAILVLAIQKAA--KLTIM--HVHLSQLAQLADADIVEISSLKIVHVLSYYYYVGMIYCGLKQWRRAAVSAPA-NIAVESYRKYVLASLLHSGKVLPKYTSSNVVRTAKVPYVEFAALFEKAALLVASSVFLEHTNLGLVKQCM--ASLTRRIVQRLTQTFITLSLTDIATHARLSK-EAEHLLVQMIESGEIHAQIDGMVAFK-DTVAAVDAKIRRSIQLHEHLSRLTADILTSSSYIKKT-- Catan2 --------------------------------------------------------------------------------------------------------------PISVEDVLKYHYYGGMLLTGLKQHERANLSIPT-RIQIESYRKLLLTSLIHTGQTGSKSDRNNPAITASEPYHLFAKAY--LSASSDSAHFEATENLGLVRQAM--SVLRAHTVRRLTNTYITISVRELAKTMGSDD-EAERIIVQMVAAGKIKARIEDMVEFV-DATGEVLDQIKAAAAA--ALAAGERVKEAEKGVLLSYAK Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 IVADALKLAKSALQALAQLSVLDQ-LEEFRLAKAL----ARVLSIVENLNAQMLSSKTVNIVETLEETKAIKAQVLAPNANTG--LTPL--HVECLKQCLLSGVPFDAFGAHRARAFMEYHLYAGMVCVGVGALDTAVFALPA-KIQIATYKRMLLLNLALHGDKLPAFFAGSHARVIEAAYASLAEMFGNLLSKIETQTLEENGNWGLAQLML--DMMPRHFIKKAAESYLRIRVEQLVQITGFAGIGASASLVQYIQELNDSSVVARVVDFL-DWSARIEARVRDIEALRKHLLQTDQHLALTKEYASGSRD Conco1 -----------AQSSTSITDSRSY-LDQLHTNTWLSIFSAYFLYLLKLSIPKFDIEQISVLPNLLSSLAILKLLLNLKTKIP--SLNPI--HSNILKICLKTEHAYLDIEPIQIQDYLTFHYYAALIHIGYKNYQSAVLIVPG-KIQLESVKKGILIDLLTLKDQ-DERFKKLIHRALNQKYAVLYSQFKSWKTHLLKQLFENDNNWGLLQQVT--NAYFPSKILVLKE-FKLLSFSQLGEYIGIRD-EVESILVDLIQSGKLNAKINGLVEFM-NRFDKLVGEIENTLELNKILQQAGVTAGAN---LKRTSN Conpu1 NMDMIVTSVMSRETILSSFTSVDP-LTLLHTIGVLYILSSRLRAYVDQFCQSFDPIQARYAPDRIFAAAAVQPLFNLIARYPP-SLTTI--HSIFLRACVTTASPISVIDDLHYNDNLVYHYAGGIALAALKRWGEACVTSPG-GVQFDALKRLVLVQLIHRGTMPPKNTHAVLTRLLKSPYSLLAYAYPQLGEIVEQQGFAADQTLGLVSQAL--DRAPRWSIKRLTETYLTLPLSEIGRSIAIEA-QVKALVVSMIESSEITASLDGIVTFS-DSKADVDRVLLDAQEQSVLLHRLERDMAKSREYLTKAVR Copci VMDGIFQTITSRDAALASPLSQDP-LSVVWTVGALYILVARLLDVITDFCKHFDPVQARHVPDRIQRLAAIEPLYLLLTRYPP-RLTTI--HPIFTLTCLQAEVPISNIDELTYNDNLTYHYTGGIIFAMLKRWKEAVVTAPS-TLQMEALKKMSIGQLIWKGKVLPKYTHPLLVRQFKTPYQAFINAYPHLKELLNKNLFQGEKNMGLLRQAV--DRAPRWVLKKLTATYLSLNLTEIAKAVKIEN-EVRGILLSMIEDGDLSATLETTVTFS-DNKSQIDALLLNAQAQSEYLLGLDRELGKSKEYLSKAVK Croqu1 DSSSLLALALSKTDVLCCLPEQDI-LDISHGMAYFVIIRARLMSHIQRFCSNVQSTCLVKLG--LVNFAVIDSIADLIQNYC--QLTKL--HPEFMKIALMNNVDIMRVEPIEYQDHLIYHYLAGVVQALNQNYKRAAVSAPG-TIQIEAYKKLILINLLYNSKPLPRYINNCFKSTFKKLYNDLMGLY--LVKLVQTSVFEKDRNLGLVKLCM--DSLSRKTILKHIPLYTSLPISHLTEVLHFTD-KTIELLQSMINNGELLGSI--IIKF--NGFK-LEELINKSKKLEKEMKMIQTKIEIEPEFLKKGIK CryneH991 DPSTLTSPSTTGEQLLALYEA-DE-VYEMIGGGLVYVLSARILDFAINLCELADPAQLRISHQRLLRLSVIPAITSLIQKL---NFSPI--FGALLEACLVTDIIFLNVKAPTYLDILTYYHHAGAVTMAVGDFRKAALTVPT-TIQLACAKRALLCELIVTGK----YTPIPVTRIIETSYNELAKEFEAWAAVRKAAEFEKDCNRGLIEQVV--NSIHRHMILRLRKTYIRLTVDSLARRLRVGE-RVVAILDDMIKSGEVSAILQAIVEFI-TALGRLKRADALAALLQEHLAEGSRRLGTSKEYLRKQAQ Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi -MDSFV--LDAEEQ--LERQHLDNILGALHSLGQLLVLKAKGIDQCNNFFRNCNVEQVRLAPAQYTEALGVAVLKDALNILSDNKLTPI--HTDFLQLCILSESNITHINSIAIKDILCYFYYSGIIFTAFKKYKKAVITAPA-SITVEAYKKYLIVYLIQFGSVFPKCTPAVVQRNIKKPYTEFVQSFSNIMNKASSEFFQKDSNWGLVKLSI--KSTYRRNIKKLTQTFMTLSINDIAEKVS--A-KAEQFVLKMIEEGEIFATIDGMVTFD-EILNDLDRNINNIVGLESKIKEMDEKISLSNNYLKKL-- Dmel ALENYVNQVRTAEELPESLSLLDNVLETLHSLGVLYVLLAKLIQLMRDFVQRNNNEQLRYAVCAFTEFVGIRIISRAIDQIRQ-LLTPI--HADLCLLSLKADADITDISNNDAKYFLLYFYYGGMIYTAVKNYERACITTPA--IMLEAYKKFLMVSLIVEGKIIPKNTQ-VIGRFMKNHYHDLVNVYANLRIIILKEAFTRDNNMGLAKQVA--TSLYKRNIQRLTKTFLTLSLSDVASRVQLAV-EAERYILNMIKSGEIYASIDGMVLFK-DMFLNVQNNITHVLDQVRQINKMEEEIILNPMYVKKALG Enthi ---------MSKGLKFSPLTYYNELLEKYYPSSHLLILKEQTISSIKNYHENISPSMKKSLEPVVERFCLTDLVHLLLSEVPD--LSPY--HALLAHILFAKFTKYHKVQPMNSFTLQLFLYYSGCIALYNRDLQEACITTPS-KQCVAAWKKEALLCLIINYSL--------------KQFNYFIDLYQPVKFIIEASILKQDGNLGLAKQVV--VSYIYSGINKVSKAFNSISVEALARRIHYD--NLLRVGLNLIKKGLINASFGDIIVFE-EGLVELLFQLKECEQIKHHLTIREEEQMNKKGSIN---- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 SLDAALNEITSREVLFAGLLSQDP-LAILNTLGFLYLLSARLLPIIQQFCKEFDPEKARLAPERIVSLYCIPLLFDLVTRYPP-TLTTL--HTVFLRTCVATEVPITEIEDLHYNDNLIYHYAGGIALGALKKWSDAVVGSPA-QIQLEALKKLALIQLIQYGKVMPKYVSPTLLNTFKSPYGAFVNYYPLLEKLLEKGFFDSDKNLGLVRQAL--ERARRWAVKRLTGIYITLSLSEIGRAVNLVE-SVRSLVINMIQDDEIAGSIDGTVTFE-VNKTQVDELLASAQRHGATLAELDRKMGRSREFLSKSLK Fusgr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 YIDQVLTQITTKEALLSSFLSQDP-LALLYTLGALYILSSRLWAVVQEFCRTFNPEQMRLAPDRIQRMAAIQPLSDLVMRYPP-TLTTL--HSMFLLLCVATSHPITDIDDLHYTDNLTYHYTGGIALAALKKWKEACVTSPG-TLQMEALKKLKLVQLISTGKVLPKYTHPLLSRLFKTPYNLFTNAYPKLREIYEKQTFVQDKNVGLIQQAL--NRAPRWVLKKLTATYVTLHLSDIGRAVKIDD-EVRALLLSMIESDDITAQIDGTVTFS-DTKEQVDRVLKSMQDQASLLESLELEVGRSREFLSKAVK Ganpr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 NVDELLQFISMPPQYYLQSTSRDP-LDLLFSLPYTYFLAARCIQYILQFLTVFDANQVRLIPDKLCRLAAIKPLANAIQRYAL-TLTNL--HQMFVKECLLLQNDITEIDAISYTDHLLYHYYGAMIYIGLKNYERAVISAPA-NIQIEAYKKFTLVSLLLHGKILPKYTANVVFRSVKQAYQDYASAFESLRNEFNK------------------------------------------------R-KVE--------------------------------------------------------FF----- Hisca1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 SIDQVVHQITTRDHILASVLPQDP-LSVLNTLGVLYILTARMWPVVLDFCRNFSPEQARLAPDRIKSIAAIQPLYNLVSRYPP-DLTTI--HAIFLTTCVTTENPIFNVDDLHYNDNLIYHYTGGIALAALKRWPEACVTSPG-TLQMEALKKLKLVQLISIGKTLPKYTHPLLLRLFKTSYHAFINAYPQLHEIYDKQTFSAEKNLGLISQAV--ARAPRWVLKKLTATYVTLHLADIGKAIKIGD-EVRGLLLSMIESNDISAQIDGTVTFS-DTKEQVDEALLDVQQQTALLGYLEQETGRSKEFLNKAVK Lenti61 SLDDVVQHITSRETILASTFAQDP-LALLNTLGYLYILSARLLAVIESFCSNFDPKQARCAPDRIVRASALSPLFSLVTRYPP-HLTTL--HHIFLKLCVSTSVPITQVDDLHYNDNLVYHYAGGMALAALKQWHKACVSAPA-QIQLEAYKKLVLVQLIQYGEILPKYTLPAISRMFKTPYASLLKQYPMLRTLVTKDLFQQERNLGLINQAI--DRAPVWLIKKLTATYLTLGLADIGKEVGIDE-EVREIILSMIDSGEINASIDGTVTFA-DTKEQLDKMLVEAQQTSQELLQVERYMNVSKEYLTKV-- Malgl1 ------------------------------------------MEKALRLCQETD-------------------------------MTNF---------------------MAKITDFFEYMDHAGTVFAHSHALNDAITSIPT-DMQYKAAKKSILLRLLRDGSTMPLQT--LTVRTIYEAYLEFARMYEKLDQFVQETVFANDGTLDLVHWTL--SARMRHGILALARIYKTFPLRHLVAFLETQ--DVIETLTTLTNSGTLEVHVNSIVHFN--NIQNMAQTLEAAGSLSMSLKNDLAQLLTSPAVMSRILS Mellp23 STSSLIELILSKPEVLICLSEVDV-LDEVHGFGYFVILSMRL-----------------------KSLE-------LIKKNE--DLSAL--HSLFMKVCLFCGVDLVKVNPIDYQDHLIYHYFAGIIQALNRNYKRSTVSAPG-SIQIEAYKKLILISLLSEAKSLPKYLNSQFKSYFSKLYFEFVHLFLQLLGFVEKNVFLQDRNYGLVKLCI--EVLPRKKILNLIPIYKSIPIKTISKILNQTEFKTIELIQSMITNREIHARIEGILEFIND-------IIQRIKRFESQMKEIEFSIERNPDYLKKTLK Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr VLDRAAQ--------LAGVT--------LAPEQHAL-----------ALLH-------------------VL----LAWRMA--NCTFVVLRAMFEGLYAAV-----------------------MILIAHKQFERATTTLPA-EIAVAAWKKHILLSALLNRKAEQSSLSGIVSRNISVPYEDFAKALGKVAALVTRETFTRDGNLGLVKQCV--AAGDRHRVHKLTKVYVKLSFEDVKVKAGLAA-QAEAILADMIAKGTIRARINRTVAFA-DAAETIQHLVQRVQGLLQLLDTKDRAVQLSKPYIEAVSQ Morel2 SFDEIISKILANDPVFAAQSNADP-LDALHSFAYLYFLVHRCLAKVWAFVTTCDGEQVRLASHKLVKVAAIKPLAIFIQRLQA-SLTMI--HPLLAKTCLLADNDISDVKHINYKDFLLYHYYGGMIYAFLKKFERAAVSAPA-EIQIEAHKKYVLSSLLQYGRVLPKYIASAVQRTIKVAYADFATAYEKIRTELEKPIFVRDKNFGLAKQCM--EALHRRNIQDLTRTYLTLSIENITSLIGLGR-RVEGIIVRMIESGAIFATIGGMVSFL-DTMDMINTQIQKATAITAKLSAMDQAISSMPAFFNKQGS Mucci2 PIDEAIARIVSTAAQLLSYTSLDP-LTVLHSLAYLYFIGARSFEMLSHFIQVFDPEQVQAAPARLLHLAPLQSFKTAIERFSS-NLTSL--HAPFIRACISANRDIEILDDISIQRFLEYYYYGALIYIGNLDYDRAAISVPTQKIQVAAYKNFVLASLIVDGQVLPKYTAQGVEKVCRSAYLSLVKAFTEFHDVASKGIFEANKHMGLVKQCL--QSLRRKIIEELTNVYITVGLNEMADKI---Q-ELELILIEMINQKQVSATM-KMVHFV-E----LEDRIFNIAAINERVSIMNKLEGLNRDFQTKYMT Mydma -MEEIVAAIRGKEYFNGSTSAIDITMNALNTLGYLYLMVFKVFDQFQQLVKNGCKEQIQQGLEKLVKCLGIHVFSEAILKVQT-NMTSL--HSDLFQLCLSADVDVTDINSFDARSFLLYFYYGGMIFLALKQFEKAVITTPA--IMLEAYKKYLLLSLLLNGKILPKYTSPVVSRSIKSPYTELAEAYFTLRAVANKSVFHTDKNIGLVKQVM--ASLVKKRIQKLTKTFLTLSLSNMAARVNLRS-EAEKFLLNMIAEGTIFATIVAMVSFH-DFFSKFDSEITNCIHLNERLQIMDRELQTNPQYVQRMLN Neucr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 QLDEIIALLQSNEEQLRAYTSLDP-LTILNSLGYLYFITARCFELLSHFISVFDVQQVLGAPARLDTLAPIQPLADAIQRLNP-ELTTL--HAPLVKACLISDSDIDHVDGVTIVDFLEYHYDASLIYIGNKQFERAAISAPA-NIQFEAYKKYCLVSLIQDGKILPKYTATVVDKGFKEHYITIAKAYEQFDELILSGTLEQDQNFGLAKQCA--VALRLKKIKALTKVYKKVDIQDIAVKLDPKF-QVEQMVVRMINTDQISATIRKMVSFH-DT-QHLQAEWKRVAAVSERTAKIDKEKGLDKAFQSKFMV Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 SLEGLVHQITTRETVLASLLGQDP-LTVLNTLGVLYILSARLAAYVTNFCRNFTPEQARYAPDRIKRVAALQPLYDLVTRYPP-QLTTI--HPIFVSVCVATAVPITTIDDLTYNDNLTYHYAGGMALAALKRWDEACVSSPG-QLQMEALKKLVLIQLISKGKTPPKYTHHALPRLFKTPYAVFVNHYPQLRDLVDKQLFSTENNIGLLLQAL--DRAPRWSIKKLTATYLTLGLAEIGQAVNIDD-AVRAIVLSMIESEEISAQISGTVTFT-DTKADVDAVLLEASVQGALLEKLERDMARSREYITKVVR Polpo -MDQFV--IESEEI--LEHNHLDNILHTLHSLGYLFVLKAKIITQVINFIQVATSEQIKAAPVH--DLLGVLPLKHAICALTD-RLTPI--HSDFLILCILSTNSITDVNSIAIKDVLAYFYYAGIVFATMKKHKQAVWTAPA-HIAIESYKKYYLVFLSVHGTTFPKYTPFVVQRTIKKTYIDFGTCYLSINTKFHQETFQKDNNIGLVKLSI--RSIHRRNIKKLTQTFMTLSIRDIADNVK--A-DAEAIVLKMIEDGEIFATIDGMVTFH-EILNELEQQINGVVSLETKLRAIDEQFSVSTPYLKRLLN Pucgr2 SQNGLLDWIISPHEILASLPLIDP-LDELYPLAYFHILLCRFLSHAHKFCSALDRKQILKISRTLVSCSSIEPLLQLIRSYS--PLTPL--HHELLRISLKTNLDI-NIDHIRYQDHLIYHYLAGTVQALGKNYQRAAVSAPG-SIQLDAYKKLILVSLLSNSSPLPPYTHPQFRTVFKKAYLDLMSLY--LLTMAEKSNFQKDNNSGLLKLCI--EILPRKAIKKLIPIYTSIPIARIDSILGHLG-NARLLIQTMIQSGELNAQI--VLKFL-DTHETLKRIVERVQSTEQTIKEKSAEIERDKELLKRLIQ Punst1 SLASAVEQITSRETLLASLLPQDP-LDILNTLGVVWILSARLFDHISRFCATFDPEQARVAPERIFRYAAIKPLYDLLTRYAP-DLTTV--HPIFLHACTLASVPISNVSDLSYTDSLVYHYLGGCAWARMKRWKDACIGAPG-TIQWEAVKKLVLVQCISTGKSLPKYAHPALTRLLKSPYGAFAKHYPALASLVEKAVFVDDNNLGLVNQAL--DRVPRWLIRGLTHTYLSLSLADIAKAVRLDE-RARDTVVSMIDEDVITATLEGTVTFA-DSKAEIDRILLGAQQQGLLLTKLDRALAGSREYLTKVTC Rhior3 SIDELIARILSSQQQLLSFTSLDP-LTILQSLAYLYFITARCFQLLSHFVQVFDVEQVVLSPTCCLHLAPLEVLLSAIQRYSG-SLTSL--HSTFVKACILADYDIETIDDLDIQSVLEYYFYGSMVYIANKNFVRAVISAPTQKIQIAAYKKYVLVCLIGEGQMLPKYTASTVEKVCKVVYLQLVDAFKDFQDIASRTIFENDKHIGLIKQCF--QSLLRKKIKELTKVYITVGLNEMAKKI---K-ELELILIEMV--------------------------------------------GCN--------- Rhoto1 SIDEIVKAISTDKAASHSRASRDP-LDVLHSVGYLWILNARLVQKVNDWVSASDVEQARLSLA-LCTLAPLQPLNTLLTRFPL--LTSL--HTLFLRCVMASSRDITDVDPIRYQDHLLYHYLGGTILALLGNYARACVSAPS-SIQIDAYKKLVLVQLLAYGKTLPRYTSQVVLTAAKAPYLEYCSAFASVDQAREKEAFEKDYNSGLVAFCD--ESLRRRQIQNLTETYITLSLGQIASYVGL-S-ERDLEIVKMITSKQIYAELATTVTFT-DTVARVTQAIEKAQVLQQRWDREQQKVEASKEFVTKAWS Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -MDAS------ASTSIAAVTTQDAIADVLHPLPLAILLLLQQIAYVSALFHNGDITKIQQCPEPLSRILGVLAVKALLQRLV--A-TYCALHTEFAKLAVAAAHPIYDIYGADTERVMSYLYYKGLVQIGMKQHAAALSNYPG-EIAVEGYKKLALLSVIVHGRASSNSIGVSVLSRINSKYNAFAEAV--VDRLMQSDMFREDNNMGLAKQCV--EAAKRHRIQRLTKTFITLSLDAITQRAALNR-EAQAILEDMIHSNQLCATIAGVVSFH-DLQE-LQSNFQKTAELYQAARRTNEAIETSTTYIK--QS Schco3 SLDSVLHQIVGRETILSSTTSRDP-LALLHTLGMLWIITARLANLILDFCEHFDQAQARAAPDRLMRYGSLNPLRSLVLRYPI-DLTPI--HPIYIWVVHTTNYPITDLDELDVQNCLMYAHLAGMTMALLQLLASACITHPG-NMQLESLKHLRLVQCIGYGETLPKYVSAMLLKMFKTPYSAFVAAYPQLQSIFDKGLWVEENTFSLMQLAL--DAQPKWALKRLTETYVTLRLADIGREIGVKE-EVRALVLSMIESETIHATI-STVTFV-DSKAQIDAVLRAAQQQGSILESADRQLGLNKDFLSKAVR Schpo1 --------MVA----------EDP------------------LLKFTDFVHQHSVEQCNQLSMYVEYAA----------------ISVM--HVCYLKELLRQSFNDLEVSHIPGSILLQYCMYAAYHCLGNNDLDSAILYIPT-TFHEEAYYSFLLLYIITTGKKLDSATSSNVL-PLKVPYEEFLDAYLKLRTVIKESRFLKDNSTAFILFAL--EVYPMHRLKKWRKTFSSLKLEYIAKQLAIS--DVAKEIIQTVANGEIFLTF--------DMHSDLCQQLIEASKN------FEASIRLKSVIYSKIMA Sorma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVGL----------E-EAELLVLKMIEKGRIHAKINGTVSFD-ETTLLLNAQIESLIKLNQSVLLADQHVQDTMDLAK---- Spipu1 -MDDLLRQIKASSAVLCSCTVQDP-LDLLHSLAYLFILVARMLQAAMRFAEQFERDQVLLAPEQTARLASVRPIQIACIRWSG-SLTSL--HRMVLKCCLLADRDITEIDDLKYQDFLLHYYYGGMIYVGLKRFERACLTAPG-FIQVEAHRKYILVSLILHGRSLPKYTNSAVFRACKAAYLDFAHAYESIETEFRKQQFEIHGNRGLVMQSM--TALVRRNIQQLTQTYLTLSLSDIAKSVKLSA-EAERIVLQMIEDGEVFATIGGMVSFR-DTMRRLKGEVTQAIDLGERVIRMDRALGLSKDFLSKILH Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 --------------MAESTPA--------WTVGVMYILPARLMSFIAEFCRRFDQTQARLVADRIVYRAAIPPLHNLLSRYAP-SLTTI--HPIFLTACVQTSTPITEISDLTYQDHLIYHYLGGIALAALKKFKLACASAPV-GLQLDAMKKLVLVQLILYGQSPPRYTFPTITNSIRSVYGAFAKVYPGLMQIVNKGVFDRDENAGLVKQAL--SRAPRWAIKKLTETYLTLGLREIGAAVGVGE-IVRGIVLDMIEHKEINASIDDTVTFA-DSKSDVDRALAEAQRQEALLREVEGALGRSRDWLAKAMR Tapde11 --------------MSISYTA----LEAI-------------LKVATDYLRNLQPAQL------LLEVLFIDFLYAVLRQYPQ--LTPV--HGILVRTACSMEQSIEYLPYLTYIDHLTFHFFGALCHAATGSWSRAVLAAGG-HFQLEAYRKFVLIGLIYHGKLFPTTTPSNTRRSLEAEYIELAEQYLVFLMLANASRMKDHGNDGFLRTAV--ASLPGHKILQLRNVYSSIYLPDLAARIGTD--GTAELLAEMNADGRLTSTTQGIVDFP--QLIKLEEVYRSIDDMSTRMSSLQKRLELEPEYVDRQLG Thetr DVETLTQSILAAKHLKSSSSLVDELPGALHTLGALYIFVAYGVTNVTNFVLAADKEQLELAPEALVKVLVIRPLMELARKLP---VNEA--HPELMLACIRSATPVDELEQLRPRELLQYLYYAGVVCIGCKEYGEALFSVPY-----------VLASLLEHGKVLPKYVPDMVARHLREAYDALAAAFAGLDAALVEPALVDDGNWGLAKLAR--HALTQRRIHDLTATYVTVSLESIAASVGLAD-DALVHVLAMIRRGQIHASVTGMVQFH-ATMRKLHETIAACADLTRKVRNLDTDLYLDPQYIYKAEL Treme1 NMETLI-----TDEILACREF--D-ISLLMTAGLLYILEMRLYNDASRLCQIADTTQLVLCQKQFLE-SVIEPLSNLIQN----HLTPI--HHIFLEACLSANHIYLDTKHPTYLDVISFYHHAGLICAARQEFSKAAVTIPT-SIQLVSAKRAILCNLLSTGKKFPRYTSSAVTRLLEQPYERISKSFDEWSGVLDHKIFDEDYNRGLINQLI--NSIIPRKILKLEQTYSRLTIPQLLQKLSFDD-QLLSILDQMIQSNSLQAQISKSITFL--QL--LQTAQ-MSSYLSTELNNINSELGIRPDYLKRIVK Trire2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 STDEAVAHVVSTLTTYLGKCSADP-LDQLQSLGYLFFITTRCLRRLIFFISTFSPEQVYLAPERLSHLAPVRPLRTAIQRFCG-DFTSL--HASLAKYALLADWDIEHVDDTNIEGFLSYYYYGAMIYIGNKKYGRAAISAPS-QIQLECFKKYVLLSLIHYGKLLPKYTATVISKFVRRQYISFADVYETLTTALEKEAFEKDNNWGLAGQCL--RALQQQKIQGLTRTYITLSVSDIAKKVGFTT-EVEKNILEMVEQGSIFASIDEMVSFH-DSLAILDEKISQAVMVGERLNRQDKSTALDRDFMSRVSH Ustma22 GIEDTLALILEESSVRTASSSLDP-LSALHSVGMLYILAARALPHITAFVQRFNLAQVQLAADKFTALGALQLLQALASRFLT-SITTL--HPMLAYQYLKTDLPLIDADPLTHSDVLQYFYYAALIYIKLDRLHDACISSPA--IHMDAYKKLVLVQLLADGKTVPRYTPQLITRMFNQPYTLFVAAYEKVYRLAEENAFEKDRNVGLIRRCL--AVYRQRKIQKLAQVYSALSLGAIAQKIGLEP-SVYADVQEVVRKGWVRATLNWMVCFN-ISISLLEDKIRIAKQWQTLLQQRDRQIGKSPTYLIRALK Walse1 TTSSLTSQTASKEPTGAGTTAHDIQLRILQSLFYAF------IEHLHAFDEK------------ILIFSSLHPLKHLLTVFTNGNLTPL--HKLFVKACITSERGINELAHLTANDNLHYFTGSATLFIMLERYEDAIVTLPITTMILRAYKQLILLQLIVNGQLLPKYTSGNLNKSLKSGYHSLVEIGAKVEQTLNHASFTKDNLLDLALKAE--DSVFAAQISAYSMIYTAMPISDLANVLGIS--HNDQLINKYIHNGAVNAQLENVIEFA-SLMIDLENAIKGSLSLRSNMQELDRKLTLNPAYVKHHIQ Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3355.fasta_al_trimmed; alignment length = 316] Allma1 YNKNFYRATWILTALDAGFWTAMNIK-PKFLRDLMSIVFTTFYLVFADQAEAKVRRLRSTVSMMRVSWEKHPYIQKLAIQIQRLLYYAGVILHVHGGGFVCMDPECHEDYLTQWAHMAPGCLVALNYGKAPEYPFPYGLEENFEFYRLIRETNGECLGLSGDSAGGNMATGVTLRAIEVMVPTALVLIYPHLNFNMGSWLEPGETQMLRVENPLVLTSHMANFNDRVLTPEMMRALALLYAGPFDLQSDYHLSPILTPEALLVKFPKVYLICGEKDPLVDDTIIFAGRLRDDVAEVTILEGVSHAVLQMSAFLPEA Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 YSRSFFRATWVTTALDAGFWTAMRIK-PKWLRDIASLIFTVYYLFAAEQADDMVRRVRATVEHLRVSWNKTPYLWALQIRIPRPLYFDGVILDIPGGGYVAMNPRNSEDRLLAWAGKTKLPILSLDYKKAPEYPYPYALNECYDVYHMIITTRGRCLGLTGDSAGGNLAVGTVLMILQMPRPNGLVLAYPSLNMRVESWMTEEQMSLIQDKTRLAVSSMISYVHDRILTPEMMRAMIILYIGPPDFSTDFLLSPVLAPESLLTRFPKTYFITGERDPLVDDTVIFAGRLRQDHVEVSLLPGVSHGFLQMAGFFPDS Aurde31 YSRAYYRATWIVTGLDAGFATAMTVK-PKWLRDICSVIFSIYYIIYANEADEKLRKFRATVEMLRVTWEKNPYVS---LLLPRPLFFAKLILDIPGGGFISMSPANHEERLRRWAISTGKPVLSIDYSKAPEYPFPFALDECFDAYRVIAESYGRLIGMTGDSAGANLCVTTIFKILEILHPVAVVLAYACLDFNFTSWMTPANMRVLRSETRLAMTSRTGYFQDRIIAPSMMRAMAILYVGPPDFGTDYYLSPILASNALLARFPRLLMTCGEKDPFVDDTVIFAGRIREDWVQMEIMEGWSHGYLQMTSLLPEA Batde5 YTRNFFRATWIMTSLDAGFLTCMHMR-PKWLRDVLSPLLSIIYMFFPESADHKVRTFRNTVEIMRCSWEKNPILRLFTITIPLPLYFDGLIFQIPGGGFVTTTPTHHDDYVSSWARQVRVPIVSINYGKAPEFPYPWALEECYEAYRSIVESNGEVIGMTGDSAGANLATGVIFKCIEAKPPAAFICVYPCLSYDMACWIPPRQLNLLRAESALSMTSRMSYFSDRIITPELLRGMALLYLSGPDLMHDHYLSPVIASDEILARFPKTYFIVGEKDPFVDDTVIFAARIREKMVKVKIIQGISHAFFQMMTFLPEA Botbo1 YSPAFYRATWIVTALDAAFATAMSIR-PKWLRDICSCLFTAYYLVYATEADEKLRRFRATVEMLRVQWEKNPYIRAATIYLPRPLFFSHLVLDVPGGGFISMSPRHHEDRLRHCAGRVGRPVLSIDYGKAPEYPYPWAIEECFDAYKVLIESKGRVIGMMGDSAGGNILTSMLYKVIETPLPIGIVLNYAVLDFNYTSWMSESQMRVMRAETRIAMTSRVGYFQDRIIGQSMMRAMAILYVGPPDFATDYHLSPILAPSEMLAQFPPMLMTCGEKDPFVDDTVIFAGRIREKWVEMRIYEGWSHAYLQMSSLLREV Botci1 YTRSYFRATWVTTALDAGFWSAMRIR-RKWIRDFAGVIFTFYYLIAAEQADEKVRKVRGTVDHLRVSWNKTPYLGFLSIRIPRPLFFDGIVLDIPGGGFVAMDPRTNDDKLFAWAGKTGLPVLSLDYKKAPEFPYPYALNECYDVYSTIIASRGRCVGLTGDSAGGNLAASTTLMIIELPIPDGLVLIYPGLDMNIGNWMSDEQMSLIKEKTRLAMSSMISYFNDRILTPEMMRAMIILYIGPPDFSTDYLLSPILAPDSLLAQFPKTYFITGERDPLVDDTVIFAGRLRRDAAEVMLIPGISHGFLQFVGIFPEG Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------MPIK-PKFLRDTLSIVFTLFYLVFANRATT-------------------------SIHLPRALFFSGVILHIPGGGFVCMGPDCHEDYLVDWAHRSPYTLVA---------------------------TNGECLGLSGDSAGGNLATGVVSRCIEVMLPDALILIYPHLNFDMACWLSPQQQTLLRVECPLALTSHMAHFNDRVLTPEIMRALALLYVGPVDLEHDYYLSPIRTPDHLLAQFPKTYLLCGEKDPLVDDTVIFAGRLRDEVCEVVIMEGVSHAVLQMHAFLPEA Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 YSRSYFRATWVTTALDAGFWSAMRIK-RKGLRDFLSIVFSIYYMICAEQADEKVRKIRATVDHLRVAWNKTPYLGALTIRIPRPLYFNGIVLDIPGGGFVAMDPRNHDDKLMGWAGKTGLPVLSLDYKKAPEHPYPYALNECYDVYHMIMASRGTCMGLCGDSAGGNLAVGMVLMVLQLPPPVGVVLVYPALDMNIGNWMSDEQMALIRDRTRLATSSMISYFNDRILTPEMMRAMIILYIGPPDFSTDFLLSPLLAPESLLAKFPKCWMLTGERDPLVDDTVIFAGRLRQNWVNVDLIPGISHGFLQFVGVFPEG Coere1 YSRSFYRATWVFTALDAGFWTAMWIR-PKALRDVLSLVFSLYYLVFAGRGAEKVRKVRATVDHLRVSWEKNAVLRALRVMVPAVVMYAGVVLDIPGGGFVGMGPRSHSDYLSAWAQRTGAVVVSVDYGKAPEYPFPYAIDQCYAVYRELVQSNGRCIGLAGDSAGGNIAASLMFRILELPVPDGIVFVYGCFNVDIRAWMTREETRALLGA--LTMGSSFTYFSDRVLSPEMMRAMILMYVGPPDFRTDYYLSPLVAPEHLLARFPPVYFMCGEKDPLVDDTVLFAARIRAPLIKVKLVAGMSHGFMQMYSLLPES Conco1 YSRNFYRATYIYTALCAGSLAANPIK-PKFLRDTVALFFIFYYLVFPNHAESRMRATGRTAQAMRVAWESNIYLQCISVWIPRGIVFNGLIFHIPGGGFVCMPPERHLAYLKKWAQDTKYPVISFNYHKAPEHPYPYALNELFDAYRTICSTHGRCLGIAGDSAGGNLCASLMLLILEVPRPRGIVFIYPALEFNMGVWMNNDELKLFRQQNPLAMSSKITYFDDRVLSAEIFRAVAIWYVGPGNFQSDYYVSPLLAPDHLLAQFPKTYFICGERDPLVDDTIIMSGKIRNEDVHVKLITGISHGFMNFEAFLPEA Conpu1 YSPSYYRATWIVTGLDAGFATAMSIR-PKWLKDFCSILFSVYYIIYATEADEKLRRFRATVEMLRVTWEKNPYLRIAGFLLPRPIFFAPLILDFPGGGFIAMTPEHHEDRLRLWAIRTGLPVLAVDYGKAPEYPYPFAIDECFDLYRLLVETNGKCVGMSGDSAGATIAVGTMVRILELPHPRAIVLNYAALDFNFTSWMSPAHLAVLRSETRLTMTSRTGFFQDRIISPSMMRAMAIMYIGPPDFATDYRISPILTPHHLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMVIFEDWSHGYLQMMALMDEA Copci YSASYYRATWIVTGLDAGFATAMSIR-PKWLRDIASIIFTIYYIIFAQEADEKLRRFRATVEMLRTTWEKNPYIRFITILLPRPLYFAPLILDFPGGGFVAMTPEHHEERLRMWAVTSGRPVLAIDYGKAPEYPYPFAIDEAFDTYRVLVESNGSLIGMCGDSAGGTLAVNVVVRILELPLPIAVLLSYPALDFNFTSWMSPENLRVLRSETRLTMTSRTGYFQDRIISPSMMRAMAILYIGPPDFGTDYRISPLLTPDHLLAQFPPLLLQCGEKDPFVDDTVIFAGRVREDWVQMVLFSDWSHGYLQMPTLMSEA Croqu1 YSRGFYRATWINTALDAGFSTAAPIR-VKWMRDVLSLIFSGYYLVYANEADEKLRKYRATVEILRITWEKNPIVRFFTFILPRPLYFARLIMDIPGGGFIAMSPLHHEDRLRRWAIKTGMPILSMDYHKAPEYPFPYAIHECMDAYRLIQETKGRVIGMTGDSAGANLSAAMMISMLELPPPVGMIWMYAALDFNFTSWMSAENLRVLRDDTRLTMTSRTGFFNDRIISPSMMRCMAICYIGPPDLTKDYHISPIFAPADVLARFPPVYLVCGEKDPFVDDTVIIAGKIREDWVQMRIFEGWSHGFAQMLALLPEV CryneH991 YTRSYYRATYVNTAFDAGFSIAMNIR-PKWLKDICSMLFSAYYLAYASEGDEVLRRFRASVEMLRTTWEKNPYIRLITVTIARPLFFPGLIVDFPGGGFIAMGPECHEERLRIWAKRTGKPVLGVDYGKAPEYPYPWAIEEGFDAYRTLMETKGEVIGITGDSAGGNICATIMLRILEIPKPVSMILAYPALDFNFTSWMSPQNLRVLRTETRLTMTSRVGYFQDRIISPSMMRAMAILYIGPPDFETDYYISPILAPPHLLAHFPPVYFISGERDPFVDDTVIFSGKIREDWVQMRIIEGWGHGFMQMSSLMREV Crypa2 YSATYFRATWVLTALDAGFWTAMKIR-QKWLRDIASLVFSVFYLFAAEKADEKVRKVRGTVEHLRVSWNKTPYLSFCQIRIPRPLYFDGVVLDLPGGGFVAMDPRCNDDKLLSWASKTGLPILSLDYKKAPEYPYPYALNECYDVYATLIKSRGRCIGMTGDSAGGNLATSMTLMIVELPTPEAVILFYPGLDMNIGNWMSDEQMALIKDRTRLAMSSMISYFNDRVLNPEMMRAMIILYIGPPDFSQDYLLSPILAPDMLLARFPKTYFLTGERDPLVDDTVVFAGRLRRAIAEVVLLPGTSHGFLQFPTIYPPA Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 YAPEFNRAAWINTALDAGFASALSIR-PKWLRDICSIGFFMYYLFNGDEAEGKVRRLRETLEFLRGTWDKNIYLRAITIIIQRPLFFDGLILDFPGGGFVAMSPTHHEERLRAWTKRTQRPVLSVDYGKAPEYPYPFAIEEGFDLYCTLSESGGRIIGMSGDSAGGNIAVNVMFKLIEFPRPVGLALTYAALNFSFGSWAWPS--------TRLTMSSKAGYMHDPIITPSMMWAMCLLYLGKPGVERDYHLSPLLAPSTLLAELPPILLQCGARDPLIDDTVLFGGRVRADDVTVQIFPGWSHGYLQMSALMPKA Fusgr1 YDATYYRATWVLTALDAGFWTAMKIK-TKWLRDMASIVFSLFYLIAAEKADEKVRKVRGTVEHMRVSWNKSPYLSFFQIRIPRPLYYDGIILDIPGGGFVAMDPRCNDDKLFSWAAKSGLPILSLDYKKAPEFPYPYALNECFDVYKTIINTKGRCVGLTGDSAGGNLAVAATLMIMELPAPDGLICFYPALDMNIGNWMTDEQMSLIKDRTRLATSSMISYFNDRVLTPEMMRAMIILYIGAPDFSQDYLLSPVLAPEALLVDFPKTYFMTGERDPLVDDTVIFAGRLRRDAAEVMLIPGTSHGFMQFPTVYPPA Galma1 YSPSYYRATWIVTGLDAGFATAMSIR-PKWLRDISSIIFSAYYIIYAQEADEKLRRFRATVEMLRTTWEKNPYIRLVTILLPRPLFFAGLMLDFPGGGFVAMTPEHHEERLRMWAVSTGKPVLAIEYGKAPEYPYPFARDEAFDVYRLMVESCGTLIGMSGDSAGGTLALNVVIKTLELPLPTAVVLNYAALDFNFTSWMSADNLRVLRSETRLTMTSRTGYFQDRIISPSMMRAMAILYIGPPDFATDYHISPILAPSHLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMVLFSDWSHGYLQMPTLMSEA Ganpr1 YTRNFFRATYILTALDAGFWTAMNIR-PLWLRDVLSVLFSAYYLLVPNEAEKTSKAFLSTVEMMRISWGKNPILHLISISIPRPLYFDGVVVHYPGGGFVAMPPQCHEDYVTIWATRLRVPIVSVDYGKAPEYPYPYASEQCFDVYRSVVESNGAVLGLAGDSAGANLCTTTTIRILELPPPSAVLLVYPVLSFDMAAWMPPGDISMLRNEPSLSMTSRLSYSFDRILPHELIRGLALLYLGCPDFQGDYILNPVIAPDDVLARFPRTYILCGEKDPFVDDSVIFSARLKREMVHTRILEGFSHGFLAMRAFLPEA Gloin1 YSRNFYRATWILTALDAGFWTAMSIR-PKFLRDIMSIVFSIYYLIFADQADEKARRIRATVECLRVSWEKNPILRAAIILIPRPIYYDGLILDFPGGGFITMPPPCHEDYLCHWAKKTHVPILSIDYAKAPEFPYPYALEECFDVYQSIMESNGEAIGMVGDSAGGNIVTSVMFKILELPHPNALILIYPCLNFDITCWMSPSQLSVIRAETRLAMTSRMSYFNDRILNPDLMRAMAILYLGPPDFTSDYLLSPIVGPDELLAQFPKVYLMCGEKDPLVDDTVVFAGRIREDWVEVKILQGISHAFLQMLALLPES Hisca1 YSRSYFRATWVTTALDAGFWTAMNIK-RRWLRDIASIVFSIYYLIAAEHADEKVRKVRATVEHLRVSWNKTPYLSFLGLRIPRPLYYNGIVLDIPGGGFVAMGPRMSDDKLLAWAARTGVPVLSLDYKKAPEYPYPYALNECYDVYHTIVSSRGRCIGLTGDSAGGNLAAGVTLMVLQLPPPVGLVLIYPSLDMNIGSWMTDEEMSLIRERTRLAVSSMISYFNDRILSPEMMRATIILYIGPPDFSSDFLLSPLLAPEALLARFPKTYFLTGERDPLVDDTVIFAGRIRQAHVEVSLIPGISHGFLQFPALFPEG Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 YSPSYYRATWIATGLDAGFATAMSIR-PKWLRDISSIIFSFYYILYAQEADEKLRRFRATVEMLRTTWEKNPYIRLVSILLPRPLFFAPLILDFPGGGFVAMSPEHHEERLRMWAVTSGRPVVSIDYGKAPEYPYPFAQDEAFDTYRVLVESCGSLLGMSGDSAGGTLALNVVLKALELPLPTAIVLNYAALDFNFTSWMTADNLQVLRSETRLTMTSRTGYFQDRIVSPSMMRAMAILYIGPPDFATDYHISPILAPARLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMVLFSDWSHGYLQMPTLMSEA Lenti61 YSPSYYRATWITTGLDAGFATAMHIR-PQWLKDICSILFSIYYIIYAHEADEKLRKFRATVEMLRTTWEKNPYIRLVTILLARPLFFAPLILDFPGGGFVSMTPEHHEERLRMWAIRTGKPILSVDYGKAPEYPYPFSIDECFDLYRVLVETTGMVIGMTGDSAGAHIAVTVMFKILELPHPLALVLNYAALDFNFTSWMTPQNLRVLQTETRLTMTSRTGYFQDRIISPSMMRAMAILYIGPPDFQSDYQLSPILAPDHLLAQFPPLLMTCGEKDPFVDDTLVFSGRVREDWVRMVIFSEWSHGYLQMPSLIREV Malgl1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 YSRGFYRASWINTALDAGFSTAAGVR-IKWMRDVLSLLFSGYYLVYANEADEKLRQYRATVEILRVTWEKNPFVQFFTFILPRPLYFARLIMDVPGGGFIAMSPMHHEDRLIRWTMRTGVPILSIDYCKAPEYPFPYAIHECMDVYRLVQETKGRVIGMTGDSAGANLSAAMMISMIELPPPVGILWMYPALDFNFTSWMSEENLRVLRHDTRLTMTSRTGFFNDRIISPSMMRCMAICYIGPPDLTKDYHISPIFAPASVLARFPPVYLVCGEKDPFVDDTVIIAGKIREDWVQLRIFEGWSHGFAQMLPLLPEV Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 YTRGYTRGLWILSALDAGFFTSQNIR-PKPLRDTMSAIFSIFYLFFPKRAVEKNNMMLKTATHMRRSWEKHPVIRLMTIVVRLSILFKGIILDIPGGGFVAMRPSCHADYLMAWAGQTNIPIISIDYKKAPEFPFPHGLNECFDIYKMIVATKGACIGLAGDSAGGTFSASVMNMIIELPKPVGLLMVYPCMHVGLDFWMSNSDLAVIEEEDGMTLNSKAAFMDDQVLGSSFLRALMVMYIGGLDHKSDYLVSPIYTPDHILAQYPRTYIITGEKDPLVDDSIIFMAKMRRESDALRIVSGVSHAFMQMTGIVPEM Mucci2 YKRSFYRATWILTALDAGFFTAMPFK-PLWLRHVLSLVFSAYYLVFADSAEEKVRKTRSSIEQMRTSWEKNPILGFVSIHVDRPRYYTNILLQFPGGGFVSMPPPCHEDALAAWAKHTGFPVFSVNYKKAPEYPYPWPIEECFDLYISIIQSNGRVLGLIGDSAGGNITAAVTLKILALPVPIGLILIYPALDFEMSCWMSPSQLSLIRAEARLAMTSRMSFFNDRVITPDLMRAMAILYLGPPDFENDYLLSPVHAPEDLLAHFPKTYMMCGEKDPLVDDTVIFAGRIRQDGVRVKFLEGMSHAFLQMMPFLPEA Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 YDAAYFRATWVLTALDAGFWTAMKIK-QKWLRDISSIAFSLFYLVAAEKADEKVRKVRGTVEHLRVSWNKSPYLRFVQIRIPRPLYYDGIILDIPGGGFVAMDPRCNDDKLFSWAAKTGLPILSLDYKKAPEFPYPYALNECYDVYSTIIKTKGRCIGLTGDSAGGTLATSMTLMIVELKVPDGLILFYPALDMNIGSWMSDEQMALIKDRTRLAMSSMISYFADRVLTPEMMRAMIILYVGPPDFSSDYLLCPILAPDILLSKFPKTYFLTGERDPLVDDTVIFAGRLKRQAAEVALVPGISHGFLQFAGVYPPA Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 YSRSFFRATWITTGLDAGFWTAMNIK-PKWLRDIASLVFTAYYLIAAEQADEKVRRVRATLEHLRVSWNKSPYLWSLAIRIPRPLYFDGIVLDVPGGGFVAMSPRNSEDKLLSWAGRLKVPILSVDYRKAPEFAYPYALHECYDVYHSIIATNGRCMGLTGESAGGNLAVGMTLMVLQLPAPDGVVLGYPALNMRVESWMSDEQMSLIQEKTRLAVSSMITYVHDRILTPEMTRAMIILYIGPPDFNTDFFLSPVLAPDALLARFPKTYIMTGERDPLVDDTVIFAGRLRQDYVEISLIPGISHGFMQMAGFFPDA Phybl2 YKRSFYRATWILTALDAGFFTAMTLK-PMWLRHICSILFTFYYLVFADAAEERVRRVRASIEHMRVSWEKNPILRTMSMSIDRPFFYAGILLQFPGGGFVSMPPPCHEDAIAVWANQTGLPIVSVNYKKAPEHPYPWPIEECFDIYLRLVETRGTIIGLLGDSAGGNISSATTLKIIALPMPAGLILIYPALDFEMSCWMSPSQVSLIHADSNLAMTSRMSFFNDRIISPDVMRAMAIMYLGPPDFETDYLLSPIIAPLELLAEFPKTYMICGEKDPLVDDTVILAGRIRQNAVHVKFLEGISHAFLQMMAFLPEA Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 YSPSYYRATWIATGLDAGFATAMSIR-PKWMRDLCSVLFSVYYIIYANEADEKLRKFRATVEMLRTTWEKNPYIRVFTILLPRPLYFALLILDFPGGGFVAMTPEHHEERLRMWAWRTGRPVLSIDYGKAPEYPYPFAIDEAFDTYRVLVESKGVLMGMSGDSAGATLAVNVVIKILELPQPVAVVLNYAALDFNFTSWMSPDNLRVLRSETRLTMTSRTGYFQDRIVSPSMMRAMAILYIGPPDFTTDYHISPILTPSHLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMVLFSDWSHGYLQMPSLMKEA Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 YSRGFYRATWINTALDAGFATAAPIP-VKWLRDLLSVLFSGYYLIYANEADEKLRRYRATVEVLRITWEKNPIIEFFTFIFPRPLYSSRLILDVPGGGFIAMSPFHHEERIIQWTIKTGIPILSIDYCKAPEYPFPYAIHECMDVYRIIQESKGRVIGMTGDSAGANLSAAMIISILELPLPVGILWLYAALDFNFTSWMSPENLRILRRGTHLTMTSRTGFFNDRIISPSMMRCMAICYVGPPDLTKDHHISPIFTPSSILARFPPVYLVCGEKDPFVDDTVIIAGKIREDWVQMRIFEGWSHGFAQMLSLLPEV Punst1 YSPSYYRATWIVTGLDAGFATAMNIR-PKWFRDLCSVLFSVYYIIYAQEADEKLRRFRATVEMLRTTWEKNPILRAFTILLPRPLFFAALILDFPGGGFIAMNPLHHEERLRMWAVRTGKPVLSIDYGKAPEYPYPWAIEEAFDAYRVLAASNGKLIGMSGDSAGATMTVNVMIKILEVPHPLAIVLNYAALDFNFTSWMSPDNLRVLRSETRMTMTSRTGYFQDRIITPSMMRAMALLYIGPPDFATDYHISPILTPRNLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMQIYSDWSHGYLQMPMLLKEA Rhior3 YSRSFYRATWILTALDAGFFTAMPLK-PKWLRDILSLVFSAYYLVYADAAEEKCRRIRASIEQMRLSWEKNFILKNLSISVERPRYYAGILLNIPGGGFVAMPPPCHEDALTAWAKHTGLPVISVNYKKAPEYSFPWPIDECFDLYTRILQTKGKIIGL-----GGNISCGVTMKAITLPKPIGLILIYPALDFELSCWMSSDQLSLIRAESRVAMTSRMTYFNDRILTPDIVRAMAILYLGPPDFGTDCLLSPIHTPDEILAHFPTTYMMCGEKDPLVDDTIILAGRIRQDGVRVKLLEGMSHAFLQMLNFLPET Rhoto1 YSRDYYRATWFVTALDAGFATAMNIR-WKWLRDIASLLFSAYYLLLANEADEKLRKFRATVEMLRVTWEKNPYIRFFTLFLPRPLYYHGLVMDIPGGGFICMNPEHHEERLLRWARKTGKVVVSFDYGKAPEYPFPYAIDEMYDAYSLLHATKGRCIGMTGDSAGANIATGVVLRILEPPLPVALVFAYAALSFHFTSWMSSSDLRVLRSDTRLAMTSRTAFFNDRIISPSMCRAMALLYIGPPDLHSDYHISPIFTPPALLAHFPPVYLSCGERDPFVDDTVLFAGKLREDWVQTSIIAGWSHGYLQMVSLLPAA Rozal11 YSSNFYRAAQILKTLDAGFLTSMAFK-YEPLKSFMSVLLSAYFAFFPDQAEAVTKKYRVTVEVMRISWEKHPLIKLLAFELPRYLYYDGLLLHIPGGGFVCMSPKHHHDYICILAKRLKVPILSVDYKKAPEYPYPHALNEIFDIYAVLAITKGGLLGMMGDSAGANLMTGSVLKALHLTTPHAMVMIYPFLNYDIQGWLHNEYKHLLGKKPRERLSSRMKYLDDVIITPEFLIEMAHMYLGEVNPAKDIYISPIMANDDLLRLFPPVYIQVGDKDPFFDDSVILAARMKHSFVQLKIYPGVSHAYLQMLSILPEA Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 YSPSYYRATWIATGLDAGFATAMHIK-PQWLRHICSVLFSGYYIIYANEADEKLRKFRATVEMLRATWEKNPILQAFMVLIQRPLFFAPLVLDFPGGGFVAMSPLHHQERLRLWAISTKRPVLSVDYGKAPEYPYPFSIDEVFDLYKALVETNGTIIGMSGDSAGATLAVATMVKILELPIPVALVLNYAALDFNFTSWMSAEHLKVLRSETRLTMTSRTGYFQDRIISPSMMRAMAILYIGPPDFKTDYYISPILTPDHLLAQFPPLLMQCGEKDPFVDDTVIFAGRVREDWVQMVLFSDWSHGYLQMPALMTEA Schpo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma YDATYFRATWVLTALDAGFWTAMKIK-QKWLRDISSIAFSVFYLFAAEKADEKVRKVRGTIEHLRVSWNKSPYLRFMQIRIPRPLYYDGIILDIPGGGFVAMDPRCNDDKLFSWAAKTGLPILSLDYKKAPEFPYPYALNECYDVYSTIIKTRGRCIGLTGDSAGGTLATSMTLMIVELKVPDGLILFYPALDMNIGSWMSDEQMTLIKDRTRLAMSSMISYFADRVLTPEMMRAMIILY------------------------FPKTYFLTGERDPLVDDTVIFAGRLKRQAAEVNLVPGISHGFLQFPGVYPPA Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 YTRNFYRASYVLTSLDAGFLTAMNVR-PKFLRDILSVLFAAFYLVFPDTADEKVRKFRATIEMMRVSWEKNPYLRLATIIIERPLYFTGLILLLPGGGFVAMPPKCHEDYVSQWAVISKVPIVAIEYGKAPEFPYPFALEECFDAYRSIVESNGGAIGFVGDSAGGNLVVGVVMRCLEIPPPNGLVLIYPCLSFDMSCWMPSEQLKLMRAESSLSMTSRMSYFTDRIITPEMMRAMALLYLGTVDLASDYYLSPVMAPDDLLARFPKTYLLCGEKDPFVDDTVVFAGRLRETMVRVKILEGVSHAMFQMLSLLPEA Sporo1 YSRDYYRATWIVTALDAGFATAGQIR-SKWLRDVFSLLCTGYYLLFANEADEKLRKYRATVEMLRTTWEKNPYIKFFTLFLPRPLFYSGLIMDIPGGGFICMNPEHHAERLLRWAKQTGRPVLSFDYGKAPEYPYPFAIDEMYDAYSLLHATRGKCIGMTGDSAGANIATAMLVKLLEPPVPVALVYAYAALSFHFTSWMPASDLRL----TRLAMTSRTAFFNGKLPSPERCRAMALLYIGPPDLHSDYHISPIFTPPHLLHQFPPVYLSCGERDPFVDDTVIFAGKLRE-----DIIEGWSHGYLQMVALLPAA Stehi1 YSPSYYRATWITTGLDAGFATAMAVR-PKWMRDICSVLFSAYYIIYANEADEKLRRFRATVEMLRVTWEKNPYIRLFTILLTRPLFFASLILDFPGGGFVAMTPEHHEERLRMWAMRTGRPVASVDYGKAPEYPYPFAIDEVFDTYRVLVESKGKVIGMSGDSAGAAITIGAMIKVLELPLPIAIVLNYAALDFNFTSWMTPANLRVLRIETRLTMTSRTGYFQDRIISPSMMRAMAILYIGPPDFATDYHISPILTPSQLLAKFPPLLMQCGEKDPFVDDTIIFAGRVREDWVQMQIFSDWSHGYLQMPALMKEA Tapde11 YSANFYRATWLLTALDAGFWTAMPIK-PNWIRHTASLLFSVYYLVFANQADEKVRKIRATVEQLRLSWQKTPVIKTMSVQIPRGLYFDGIVISFPGGGFVSMSPREHDDSHTAWAKKLGAPLLSIDYRKAPEHVYPYAIYECFDAYREVMTSKGAALGMVGDSAGGNYVAAVMLMLLEIPLPSGLVLIYPFLDFNITSWMSADHLRLLRQETRVAMTSRVSFFQDRIISPDMMRAMALLYIGPPDFQTDYLLSPILAPSDLLAKFPKTYFMCGEVDPFVDDTVIMAARIREDDVEMTLVRGTSHGFLQMRAILPEA Thetr ---------------------AADIL-PRLLLELAMLPMVAFYACFPAAAASAVRRAYAAAATIRALWSGSVIIRSLTVAVEAQVVAQGLVIHLHGGGFVAMSPADHADYLKTWARAPGMERISLDYPLAPEAPFPLALNDAFALYAIAASCSTAPISVVGDSAGGNLAAALGLLVAALPAIDALVLIYPSL---------------VRAR-------HTAYV------PTTLRAVS---------ATHPLISPLAAPAWLLASASRKYVVCGECDPLLDDS---------------------------------- Treme1 YSRSYYRATYINTALDAGFASAMSIR-PKWLKDMCSMLFSVYYLIWANEADEVLRRFRASVEMLRTTWEKNPYIRMITVSIPRPLFFSGLIIDFPGGGFVAMGPDCHEERLRSWAKRTGKPVLAIEYGKAPEYPYPWAIEEGFDAYRTIHETLGSCIGITGDSAGGNICATIMLRILEIPRPVSIILAYPALDFNFTSWMSPANLRVLRTETRLTMTSRVGYFQDRIISPSMMRAMAILYIGPPDFETDYYISPILSPPHLLQHFPPVYLICGERDPFVDDTVIFAGKIREDWVQMRIIEGWGHGFMQMAALMREV Trire2 YDPTYYRATWVLTALDAGFWTAMKIR-SKWLRDLASIVFSLYYLVAAERADEKVRKVRGTVEHLRVAWNKTPYLGFLQVRIPRPLYYDGVVLDIPGGGFVAMDPRCNDDKLFAWASKTGLPILSVDYKKAPEYPYPYALNECFDVYVTLVRSRGRCIGMTGDSAGGNLAVAATLMVLELPPPDGLVCFYPTLDMNIGNWMTDEQMSLIRDRTRLATSSMISYFNDRVLTPEMMRAMIILYIGAPDFTQDYFLSPVLAPEELLENFPKTYFMTGERDPLVDDTVIFAGRLRREVTEVLLIPGTSHGFMQFPGVYPPA Umbra1 YKRSYFRGTWILTALDAGFFTAMGIK-PTWLRHILSIVFSAYYLVFADDAEEKSRKVRATVEHMRTSWEKNPILSFVSIQVARPLYYAGLILHFPGGGFVSMPPPCHEDAISQWAAQTGYLICSVNYGKSPEYPYPWAMEECYDTYISIVESNGKVLGLIGDSAGGNLAAGVTLKILAIPLPAGVITVYPCLNFDLSCWMSPSQISLMRAEPRLAMTSRMSFFNDRIITPDLMRAMAILYLGPPDFDTDYLLSPIVAPSTLLSQFPKLYMMCGEKDPFVDDTVIFAGRIRQHGVTVRIMEGMSHAFLQMIPFLPDA Ustma22 YSRNFYRTTWIVTALDAGFASAMNIK-PKWLRDLMSIVFSAYYIVYANEADEKLRKYRATVEMMRYTWEKNPYVRLATLLIARPLFYAKLVLDFCGGGYICMNPQHHEERLRQLAKQMQKPVLCVDYCKAPEYPYPFALEECFDLYRTLHETAGKVIGMTGDSAGGNLATGVVLKIIQLPKPIGMVLSYPSLNFGFSSWMKPEHLRLLRQQTRLTVTSMAGYFQDRIITQGMLRAMAILYVGPPDLDNDYYLSPVVAPAHLLAEFPPVLFICGEKDPLCDDTVIMAGRIREDWVQMRIIEGWSHGFLQMSALMPEA Walse1 YSRSYYRATWLSNALDAGFATAMSIRKPKWLKDLAGPVFGLYYLFWTAEADEKLMKFRATVEFLRTTGEKNPYIRAVTVLLPRPMFFDGLVMDFPGGAFVFMTPRDHEERLRWWAKEGNKKVLSVNYGKSPEYPFPWAIDEAFDLYNILLETNGRLLGIAGDSAGGNIVTVVMFKILELKHPVGIVLTYPALDFNFTSWMSDENLEVLRTETRLTMTSRSGFFNDRIIPPSVMRACALLYIGPPDFKTDYYISPILAPSHLLEQFPTTLIICGERDPFVDDSLIFAGRLRKDWVHLRIIEGMSHGFLQMTGVFKES Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3358.fasta_al_trimmed; alignment length = 296] Allma1 RTVFLALLVDILS-FTIILPLFPRLLEYYSLFSVTLRQISNLDVVLF-GGALGSLFSFLQFIVSPWIGRLSDRLGRKVL-MLCMAGNLASCFLWVFVLSRVVGGLSEGNVQLSVSIITDITTAETRSKGLALVGLAFALGFTVGPAMGAYFASNPYSASAFAFALILAEIWY--LLIHASYLFLFSGLEFTLPFLTHDQYQFSHAQQGALLGLIGFVAAGVQGGYTRRGLIACACGFALLG---CVV------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 QVLMISLLLDLIS-FTFILPLFPSLLTFYSLLNQVFHYLSRYDIVLL-GGALGSLFSLLQAIAAPFIGRLSDRYGRRAL-LCSMVGNTLSVALWTFLASRIVGGLSEGNVQLAHAIATDISDESKRGSTMALVGACFSIAFTCGPALGAALSNNPFATAAVSLVLIVTETLY--LLLHFLFLLPFSGLEFSLPFLTATFYASPSALNGRLLSLMGLIASLLQGTVVRRGVVACTISFFLLAAGALLAVTSATVVTGLNSLGSLRGLVLGRL--RSWGQVGRAAGPLLFCSLFWWVG Aurde31 SIVFVSLVLDLFA-FTIPLPLFPRIIDWYGFLSRTLWTVSRWDVVLL-GGLMGSLFSTLQFLVSPRIGALSDKYGRKIL-LLTMAGNILSAIVWSFMLARAIGGLSEGNVQLAIAILSDITTPEARSKALSLVGIAFSICFCIGPPIGAWFATNIYAWPALTLVLLSVETAF--LIIHFFFLSLFSGVEFTLTFLTYDLFDWNNIQNGRLIGFMGIISALLQGGYVRRGVQTCTVALFLLSAATFLAFTSATVVNALNAYASVKGRAMGEY--RSWGQLGRAMGPIVACASYWTFG Batde5 KIVVIALLIDILA-FTIILPLFPRLIAHYSFYYSAAMAVSRLDIILF-GGFLGSLFSFLQFLSSPIIGNLSDRFGRRVL-LISMIGNAVSMLLWVFVWSRIIGGLTEGNVQMSIAIISDITSPKDRSKALAWVGISFALGFTIGPPLGAYLASNRYSSPAFAFGLIAFETVY--LLIHFAFLFSFSGMEFTLTFLTHDRFDFTPVQQGKLLAFMGVLSALIQGGYVRRGIISCAIGLLVVGGVAFLAFTSGTVVNSLTSLASLRGHTLGVF--RSHGQLGRSIGPILACSGYWIAG Botbo1 TVVFLALVLDLFA-FTIPLPLFPRLIEWYGLLSRTLSAVKRWDVVLL-GGLMGSLFSALQFYISPKIGSLSDKYGRKVL-LFTMIGNVLSALIWSYLLSRAVGGISEGNVQLSIAILSDVSTPATRARALSLVGIAFSICFCIGPPIGAYLSTNVYATPALTLALLLVETLF--LRMHFLFLAVFSGVEFTLTFLSFDLFDWSNAQNGRLLGFIGVISALLQGGYVRRGVGSCALALAFLAAAACLAFTSATVVNSLTALASLKGRALGEF--RSSGQLGRALGPLLACGLYWTLG Botci1 TVLVL------------------------TLLAHILTYLSRYDIVLL-GGALGSLFSLLQALASPIIGTLSDKYGRRAL-LASMTGNILSVLLWTFLLSRVVGGLSEGNVQLAIAIATDISDEKQRGATMALVGICFSISFTFGPALGAWLSTNPFATAAFSLFLIVTETIY--LLTHLSFILFFSGMEFSLPFMTYDLFGYTSSRNGRLLGYMGLVASLLQGGVTRRGVVSCLGALFLLAATTLLAVTTATVVTGLNALSSFRGGKLGNL--RSWGQLGRGLGPLLFTSVYWWAG Caeel KLLIPALICNMLA-FTSILPLFPTILNYYWLYDISVKGLERYDKVFF-GGFLGSLFSALQFISSPTLGSLSDIYGRRVI-SLCCIMTFISYVNWYFVLSRILGGLSKGNINVATAIVSDVYSPEDHPKGMALIGISYSLGFLIGPMIGAYFSTSPFAYPAFSIILTILE-FG--FWIYFLFLFLYSGLEFTLPFLTHIRFDFDNMQQGKVYLFTGLLMLPIQAKYVRKGIACIIPAYLLVAGLFFYAIASATVVTSLTSLVHVKGVLAGIF--RSLGCLARALGPVISSTFFWLLG Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ATVFFALLVDIFS-FTIILPLFPRLLEFYSLFSLTLAQLPRLDVVLF-GGAIGSLFSLLQFAVSPFIGALSDKWGRKVL-MVCMVGNLASCALWVFVLSRVVGGLSEGNVQLSVAMISDITTAETRSRGLLLV-VARRPG-------------NPYSASAFAALLIFAEIIY--LALHFAYLFLFSGLEFTLTFFTYDRFAYTNRQQGTLLGFIGLVASLVQGGYTRRGIASCALGFALLAGATMLAFTSATVVTCLTTLASLRGQAMGMF--RSWGQLGRAMGPMVACAGYWVYG Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 KVLFISLLLDLIS-FTFILPLFPKLIEFYTILSKILAGLSRYDIVLL-GGALGSLFSLCQAIASPFIGTLSDKYGRRAL-LWSMAGNILSVALWTFLASRIVGGLSEGNVQLAMAIATDISDDSQRGSTMALVGVCFSIAFTFGPALGAYLSTNPFAMAAFSLFLIVSETIY--LATHFTFILFFSGMEFSLPFMTYDLFAYQAKDSGRLLGFIGLVASLLQGSVVRRGVVSCTIAFVMLGAAALLAVTSATVVTGLNSLSSFRGNKLGNH--RSFGQIGRSLGPLVFCTLYWWAG Coere1 QVVFIGLLLDILS-FTIILPLLPRSLEAYTLLGSLLQYIARADLVLL-GGLLGSLYSLLQCVVAPFIGRAADRFGRRTL-MLCMTGNILWTVIWTFLVARIIAGLSEGNVQLSNTIIADVTDTTTRSHGMALVGIAFAVGFTIGPSVGAYFARAPFATAAFSLALLLAESLY--LLLHFAYLFFFSGMEYTLTFLTHDLFHFTNAQQGKLLGFIGISSTLLQGGWVRRGMVSCALGLLCIAGALGFAVASATVVNCLNSMVSLTGRRLGDF--RSAGQIGRTLGPVFACSVYWLLG Conco1 TLMFFSLLIDLFA-FTLILPIYPAMIDYYTLLKQILQLITKLRVTLL-GGLLGSTFSLCQFLVAPFWGRLGDKFGRRVL-LISIIGNLASNVLWFFVLSRLIGGLTEANVQLTNAIISDVTDSKTRSKGMALVGIAFSIAFTLGPSICGYLIFTPYSAAGLASILIIIEFIL--LIVHLFYLFLFSGMEFTLPFLAHDLFKFNEMEQGKMFGLMGTISSLIQGGYVRRGLLCGVLGLLSLAAIIFLSYTSATVISCLTALLSLKATVLGNF--RSYGQLGRCLGPVIACSIYWLFG Conpu1 TVVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSRTLQLVQRWDVVLL-GGLMGSVFSTLQFLVSPKIGSLSDKYGRRVL-LVTMAGNILSAMVWSYMLSRVIGGLSEGNVQLATAILSDVTTPAERSKALAHVGIAFAICFCIGPPIGAYFASNLYAVPALTLVLLIAETLF--LRLHFLFLGIFSGVEFTLTFLTFDLFDWNNKQNGALIGSIGIISALLQGGYVRRGIVSCALSLVLLGAAICLAFTSATVVNSLTSYASLKGKALGEF--RSAGQLGRAVGPLLACATYWTFG Copci TVVFLSLILDLFA-FTIPLPLFPRLIEWYGLLSQTLNFVQRWDVVLL-GGLMGSVFSALQFFISPKIGALSDKYGRKVL-LLTMIGNILSALVWTYMLSRVIGGLSEGNVQLAIAILSDITTAANRSKALAHVGIAFAICFCIGPPIGAYFASNIYAVPAITLILLAIETIF--LRLHFSFLAVFSGVEFTLTFLTFDLLDWNNTQNGKLIGSIGVVSALLQGGYVRRGVASCVLSLILLAAAVCLAFTSATVVNSLTAFASLKGKALGKF--RSSGQLGRALGPL---------- Croqu1 RIIFFSLLLDLLA-FTMPLPLFPRLIASFTLLSRMLGFISKWDVTIL-GGLLGSIFSFCQFIVSPYIGRLSDGYGRRVL-LLTMVGNIASALLWPYLLSRAIGGLSEGNVQLGIAIISDVSDPSTRAKSMALVGIAFSVCFTLGPSLGAWFA-NIYAAPAITLAFLLVETVY--LKIHSLFLFFFSGAEFTLTFLTYDLYSFTNAQNGRLLGLIGVLSSLLQGGYIRRGVGACILSLILLASAAALAYVSASVVNSLNTLASLRGKALGDF--RSAGQLGRAFGPLFATGIYWARG CryneH991 TTVFIALVLDLLA-FTIPLPLFPRLIEWYSLISRSLAFCKNWDVVLL-GGMMGSLFSFCQCIISPWLGRLADRYGRRVL-IATMVGNIVSVTIWSYLMSRLVGGLSEGNVQLSTAIISDVTTSATRSKSLALVGIAFSICFTFGPSLGAYFATNVYAMPAISLGLLLLETLF--LHLHGYFLLFFSGAEFTLTFLTYDIFSASNAYNGKLLSYIGILAAMIQARHVRPGIASCILGLLLLHAATCLAYTSATAVTGLTAAAAGRGRALGKF--RSRGQLGRAVGPLLASMLYWMEG Crypa2 KVIFISLLLDLIS-FTFILPLFPKLLEFYTLLAWILSYLSRYDIVLL-GGALGSLFSLLQAVASPVIGHLSDKYGRRAL-LTSMMGNILSVLLWTFLLSRVVGGLSEGNVQLATAIATDISDSSSRGSTMALIGACFSIAFTFGPALGAWLSTNPFATAAVSLFLILTETVY--LAAHFAFLLFFSGMEFSLPFMTYDLFGYSSAKNGRLLGFVGLVASILQGGVTRRGVTACFVAFLLLGAATCLATTSATVVTGLNALASFRGGKLGIL--RSWGQVGRGLGPILFTSVYWWAG Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel YIIFVSLLFDLLA-FTIILPLLPSLLEHYGLYAVLTDRVDRYISVLF-GGFLGSMFSFLQFVASPIVGGLSDYYGRKVL-LACASGIALSYLIWLFVLARFVGGISKGNISLCMSVITDVSSVKTRGRGMALVGVAFSLGFIVGPMIGALFAITWFVLPSLAFGLAV----G--DLVYFLYLFLYSGLEFTVTFLMYHKFGYTSMDQAKMFLTTGVIMTLLQGSVVRRSLYLIVPAFVVVGGMTLFAISTAFAVTCLTTLVSKKGSVLGIF--RSLGALARALGPVVGCIAFWCVG Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba PAAFEAHHRVASGLYAQLRYLLPDAQQGL--------------MLLV-GSLLALAASLAQFLTAVPVGRVADTYGRKAL-LVVLLATLVAHLLPAYSLSRVLAGAARGVTQLAMTVSVDLSSRADRARALAFTGIAIALGFTVGPVLGVGLARGALAGASLSTGLDLLAIMLTVLAAQLVFSCFLSAFEHSLTFILSALRGFSSADHGRLLALSGLVAILSQGGISRRGTLLLGMASCLVAVAVPFGVASGLVGPMFTALASLSNSAQRVAHFRSVGFIGRVLGPVCVTVLISLLS Fomme1 TIVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSRTLAVVHKWDVVLL-GGFMGSVFSTLQFLVSPHIGALSDRYGRKVL-LITMAGNILSALVWSYMLSRAIGGLSEGNVQLAIAIISDITTPANRGKALAHVGIAFAICFIIGPPIGAYFASNIYAVPALTLVLLSAETLF--LHTHFLFLGLFSGVEFTLTFLTFDLFDWTNSQNGMLIGFIGVISALLQGGYVRRGVSSCALGLVLLAAAVCLAFTSATVVNALTAYASLKGKALGQF--RSSGQLGRAIGPLLACASYWTVG Fusgr1 RVIAISLLLDLIS-FTFILPLFPQLLEFYTLLQHVLSGLSRHDIVLL-GGALGSLFSLLQAIASPLIGALSDRYGRRAL-LASMCGNILSVLLWTFIASRIVGGLSEGNVQLATAMASDISDESSRGATMALIGACFSIAFTFGPGLGAWLSTNPFAAAAFSLALIVTETVY--LAIHFVFLLFFSGMESSLSFMTYELFSFTSGKNGRLLGYVGLVASILQGGVTRRGTLACLASFILLGAATCLAVTSATVVTGLNALSSFRGNKLGML--RSWGQLGRGLGPILFTSVYWWAG Galma1 TIVFLSLVLDLFA-FTIPLPLFPRLIEWYGFLSRTLQFVRRWDIVLL-GGLMGSVFSTLQFFVSPRIGSLSDKYGRKVL-LITMIGNILSAVIWSYMLSRVVGGLSEGNVQLAIAILSDVTSPATRSKALAHVGIAFAICFCIGPPIGAYFASNVYAVPAITLVLLVVETIF--LRFHFFFLALFSGVEFTLTFLTFDLLDWSNTQNGKLIGSIGIISALLQGGYVRRGVSSCAVALVLLSAAVCMAFTSATVVNSLTAFASLKGTALGKF--RSSGQLGRALGPLLACASYWTFG Ganpr1 RTVFVALLIDILS-FTIILPLLPRLLDHYTLLTTFLHPIPRIDVVLL-GGVVGSLFSALQCVVAPWIGWASDRWGRKVL-MVAMTGNLISTLLWVFILSRTIGGLSEGNVQLSLAMIADVTSEEERSRGMALVGLAFSLGFTLGPPLGAYFANYPFSGAALASGLIVVECLY--LLLHWTYLLVFSGMEFTVPFLTFDRFSYTHTSQGLLFSFIGLLSSLVQGGYVRRGLGACCLGLGILSGAACLAFASGTVVNVMNSVAS-RGAVLGKF--RSAGQLGRALGPLLACGLYWSVG Gloin1 -----------------------------------------------------------------------------------MIGNIISTFLWWFVLARIVGGLSEGNVQLSIAIVSDVTTQKTRSRGLALVGIAFAISFTLGPALGAYFASNPYSMPAVALILLSVETLY--IWIHFLYLFFFAGMEFTLTFLTFDLFDFTNMQNGKLLGFIGILSAIIQGGYVRRGVLSCSIALAIISGAAFLALTSATVVNCLTSIASMKGEALGKF--RSSGQLGRAFGPIAACGLYWISG Hisca1 KVLFISLLLDLVS-FTFILPLFPSLLTFYSLLHRILHYLSRYDIVPP-SAVLSSPSS--KPLRPPFIGRLSDSPGTTRLSLCSMGG-----------------------------------DEGQRGATMALVGVCFSVAFTFGPAMGAALAGNPFATAACSLLLIVVETVY--LLTHFLFLLPFSGLEFSLPFLTTTLYDSPSAQNGRLLSVMGLLASLLQSTLVRRGVTACALSFFILSAGCLLAVTSATVVTGLNSLGSLRGVFLGRL--RSWGQAGRASGPVVFCTLFWWAG Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 TVVFLSLVLDLFA-FTIPLPLFPRLIEWYGFLSRTLQFVQRWDVVLLGGGLIGSVFSTLQFFVSPKIGALSDKYGRKIL-LITMIGNILSAVVWTYMLSRVIGGLSEGNVQLAIAILSDVTSPANRSKALAHVGIAFAICFCIGPPIGAYFASNIYAAPALSLVLLVAETAF--LTLHFLFLVLFSGIEFTLTFLTFDLLDWNNVQNGKLIGSIGVVSALLQGGYVRRGVSSCAIALVFLAAAICMAFTSATVVNSLTAFASLKGKALGEF--RSSGQLGRAIGPLLACASYWTFG Lenti61 RVVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSRTLYTVQRWDIVLL-GGLMGSVFSALQWFISPHIGSLSDKYGRKVL-LITMIGNLLSAVVWSYLLSRVIGGLSEGNVQLAIAILSDVTTPETRAKALAHVGIAFAICFCIGPPIGAYFASNVYAGPALTLVLLALETVF--LRLHFLFLGVFSGVEFTLTFLTFDLFDWNNKQNGALIGSIGIISALLQGGYVRRGISSCAMGLIFLTAAVCMAMTSATVVNSLTAYASLKGKALGKF--RSSGQLGRAIGPLLACASYWTFG Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 RIIFLSLLLDLLA-FTMPLPLFPRLIASFTMLSSILGVISKWDITIL-GGLLGSIFSFCQFLVSPYIGRLSDRFGRRIL-LLTMIGNLASALLWPYLLSRAIGGLSEGNVQLSIAIISDVSDPSTRAKSLALVGIAFSVCFTLGPSLGAWFA-NVYAAPAITVILLLVETAF--LRIHSMFLFFFSGAEFTLTFLTYDLYSFTNAQNGRLLGLIGILSSLLQGGHIRRGVIACITSLTLLAAAVALAYVSASVVNSLNTLASLRGKALGDF--RSAGQLGRAIGPLFATGLYWAQG Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 RIVFTALLLDILA-FTIILPLFPRLLQFYSLLAWSLSRLPKMDIVLL-GGALGSLFSVLQFIASPVIGKLSDVLGRRVL-LISMLGNLISCAVWLFVLSRIIGGLSEGNVQLSIAMISDITTPATRSKGLAMVGIAFAIAFTVGPALGAYFANHPFSGSALALVLLTVESLY--LFTHFAHLFLFSGMEFTLTFLTFHLFDFSHMQQGALLGYIGILSSLLQGGYVRRGMVAAAIGLGSIAGATGLAVTSATVVNCLTSLASLKGLALGRF--RSWGQLGRAAGPIAACSLYWRVG Mucci2 GVVFKALLIDLFS-FTIILPLFPRLLNYYTVLGYALTVLDKWDTVLL-GGLIGSLFSLLQFFVSPKIGRASDRLGRRVL-LYTMVGNILSTLVWLFLVARIIAGLSEGNVQLSIAIISDVTTPEKRSRSLALVGIAFAIAFTVGPAIGAWFASYPYSMAAVGLVLLVVETAY--LQIMCAFSFLFSGMEFTLVFLTFDVLDYTHMQQGKLLGFMGIVSALIQGGYVRRGMVSCVIGLYSLAGVTCLAFTSGTVVNCLTSLASLKGRALGEF--RSFGQLGRALGPISACGLYWVFG Mydma VVIFLILLFDLLA-FTIILPLFPSIIDHYWLEYIH-ELLRRYNNVLI-GGILGSLFSFLQFLSSPIVGACSDIFGRKVL-LFTMFGTTLSYIIWLFILSRIIGGLAKGSVLLCTTMMSDITTKENRGKGMVFIGLSFSLAFISGPLIGAYFASESFEKPAVSMGFQLVSIFI--TVVNFLYLLFFSGLEFTLTFVTHERFNFTSMQQGKLLFFSGVVMVIVQGGYVRRGIAIIIPSMLLIGALFLYSFAAGTVVPLLTTLFTQNGENIGKF--RSIGALSRAIAPFLTCFVYWRFG Neucr2 KVIFISLLLDLIS-FTFILPLFPKLLEFYTLLSSVLGYLSRYDIVLL-GGALGSLFSLLQAIASPIIGHFSDRYGRRAL-LLSMTGNILSVLLWTFLASRIVGGLSEGNVQLATAIATDISDPSKRGSTMALIGACFSIAFTFGPALGAWLSSNPFATAAVSLTLIVVETLY--LFTHFSFLLFFSGMEFSLPFMTYDLFAYDSAKNGRLLGFVGLIASLLQGGVTRRGVIACLLAFIMLGAAALLATTSATVVTGLNALSSFRGGKLGML--RSWGQLGRGLGPVLFTSIYWWAG Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 K----------IS-FTFILPLFPSLLSFYSLLNRIFHYLSRYDIVLL-GGALGSLFSLLQAFAAPVIGRLSDRHGRRAL-LISMLGNLLSVALWTFLASRIVGGLSEANVQMANAIVADITDEERRGSSMALIGACFSVAFTFGPALGAALSNNPYIVAAVSFALIFMETVY--LALHFFFLLPFSGLEFSLPFLTTTLYASPAALNGRLLSLMGLIASLLQGTLVRRGIVACTISFFCLAAGALLAVTTATVVTSLNSLGSFRGAVMGRL--RGWGQAGRATGPIVFCSLFWWAG Phybl2 GIVFKALLIDLLA-FTIILPLFPRLLNYYTLLGWALQLLDKWDTVLL-GGLVGSFFSFLQFIVSPWIGRASDKLGRRVL-LWTMVGNIASTLVWTFLLARLIGGLSEGNVQLSIAIISDITLPERRSRNLALVGIAFAVAFTFGPPLGAWFASYPYSMPAVAMVLLVIETLY--LTLQCLFSLLFSGMEFTLVFLTFDVLDYSHMQQGKLLGTMGILSSLIQGGYVRRGMVACVAGLVCLAGVCFLAFTSGTVVNCLTSLASLKGRALGEF--RSFGQLGRALGPVSACGLYWMTG Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 VVVFLSLVLDLFA-FTIPLPLFPRIIEWYAFLARTLQFVKRWDIVLL-GGLMGSAFSTLQFIVSPHIGALSDKYGRKIL-LITMIGNILSALVWTYMLSRVIGGLSEGNVQLAIAILSDVTTPEKRSKALAYVGIAFAICFCIGPPIGAYFASNVYAVPAITLVLLAAETAF--LRLHFLFLGLFSGIEFTLTFLTFDLFDWDNKQNGALIGSIGIVSALLQGGYVRRGVISCAVALVFLGAAVCMAFTSATVVNSLTAYASLKGKALGKF--RSSGQLGRAIGPLLACASYWTFG Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 KIIFFSLLLDLLA-FTMPLPLFPRLIASFTLLSSTLNTISKWDVTIL-GGILGSIFSFCQFLISPVIGRLSDRFGRRVL-LMTMIGNIFSAFLWPYVLSRAVGGLSEGNVQLSIAVISDVSDPTSRAKSLALVGIAFSLCFTFGPMLGAWFA-NVYAVPAISLLLLLLETLY--LQVHTAFLFFFSGAEFTLTFLTYDLYGFTNAQNGRLLGFIGILSSLLQGGYTRRGLKACISSLVLLSAAAALAFVSASVVNSLNTLASLRGKALGDF--RSAGQLGRAFGPLFATGLYWTKG Punst1 TIVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSRTLQLVERWDIVLL-GGLMGSVFSTLQFLVSPRIGSLSDKYGRKIL-LITMIGNILSAVVWSYMLSRVIGGLSEGNVQLAIAILSDVTSPATRAKALAHVGIAFAICFCIGPPIGAYFASNLYAVPALTLVLLVVETAF--LRLHFLFLGIFSGVEFTLTFLTFDLFDWSNKQNGALIGSIGVISALLQGGYVRRGMTACAVGMTLLAAAVCLAFTSATVVNALTAFASLKGKALGQF--RSSGQLGRAMGPLLACASYWTFG Rhior3 -----------------------------------------------------------------------------------MIGNLLSTLIWLFLLARIVAGLSEGNVQLSTAIISDVTTTEKRSKSLALVGIAFAIAFTLGPPIGAWFASYPYSMAAVGLALLLIETVY--IRIMGVFSFIFSGMEFTLVFLTFDVLDFSHMQQGKLLSYMGIISALIQGGYVRRGMIMCITGFYCLAGVTCLAFTSGTVVSGLTGLASLKGRALGKF--RSYGQLGRSLGPISACTLYWIFG Rhoto1 RVVILALILDLLS-FTMPW--------DFTLLSRTLECVSRWDLTLL-GGLLASLFSFCQFLISPRLGKLSDRFGRRVL-LGTMVGNVLSALLWIYAASRIVGGLSEGNVQLSIAAISDVTTPETRARSLALVGAAFSLAFTFGPSLGAYLSTNSYAVPAMTVVLLSLETLF--LRLHLLFLFFFSGAEFTLTFLTHNLFDWSNAQNGRLLGFIGILSALLQGGYVRRGMQACAGSLVALAAAAGLAFVSATVVNSLNALASLKGHVLGSF--RSAGQLGRAVGPLATTAIYWTVS Rozal11 ---------------------------------------------------------------------------------------------------------------MSEAKISD--------KGNAIIGIAYSIGFTIGPLVGILLVRDSFMVAALNFISLLVCMFF---LVALLFQFFYSGFESTLTFSAKERLNFNSREQGMLLIWIGVASIIIHGVFMRRGIIGALCSAILFPTVLGSSIATSFVNGGLSRLVVIKGEQIGKM--RKYSQLGRALGPFCASFICSSFG Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 TIVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSQTLHFVERWDVVLL-GGLMGSVFSTLQFIVSPFIGSLSDKYGRKIL-LITMIGNIASAIIWSYMLSRVVGGLSEGNVQLAIAILSDVSTPAQRSSTLAYVGIAFAICFCIGPPIGAYFASNIYAVPALTLVLLLVETAF--IRQHFLFLCLFSGVEFTLTFLTFDLFDWTNKQNGALIGSIGIISALLQGGYVRRGVHACALALVLLAAAVCLAFTSATVVNALTAAASLKGKALGRF--RSRGQLGRAIGPLLACAMYWTFG Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma KVIFFSLLLDLIS-FTFILPLFPKLLEFYTLLSSVLGYLSRYDIVLL-GGALGSLFSLLQAIASPIIGHFSDRYGRRAL-LLSMTGNILSVLLWTFLASRIVGGLSEGNVQLATAIATDISDPSKRGSTMALIGACFSIAFTFGPALGAWLSTNPFATAAVSLTLIVVETIY--LLTHLSFLLFFSGMEFSLPFMTYDLFAYDSSKNGRLLGFVGLIASLLQGGVTRRGVVACLLAFIMLGAATLLATTSATVVTGLNALSSFRGGKLGML--RSWGQLGRGLGPVLFTSVYWWAG Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 TTVFCALLIDILA-FTIILPLFPRLLEHYSTYFRMRTVISRLDIILF-GGALGSLFSFLQFISSPIIGRLSDKYGRRVL-LLSMLGNGVSMLLWTFVWSRIIGGLTEGNVQMSIAMISDVTTPETRSRGLALVGIAFSLGFTVGPPLGAYFTSNRYSSPAFAFILIVIETIY--LLIHFLFLFFFSGMEFTLTFLTHDRFGFSHGQQGRLLAFIGVLSALVQGGYTRRGIAACGIGLAVLGGAAFLAFTSGTVVTGLTSLVSYRGQVLGKF--RSVGQLGRSLGPIFACTNYWILG Sporo1 RIIFIALVLDLLA-FTMPLPLFPRIIDDFTLLSRTLSTVSRFDLTLL-GGLLGSTFSFCQFLISPRLGSLSDKYGRKVL-MASMLGNLISAGLWVYALSRIVGGLSEGNVQLSIAAISDVTTRQTRSRYLASIGIAFSLAFTLGPSLGAFFASNSYAVPAITVGLLVVETLY--LWVHFGFLFFFSGAEFTITFLTNNLFDFSNSQNGRLLGFIGILSSLLQGGYVRKGIRACQFSLLLLAAAAGLAFVSATVMKGEGQV---KGRALGKF--RSKGQLGRALGPLFATGLYWCVS Stehi1 HIVFLSLVLDLFA-FTIPLPLFPRIIEWYGFLSRTLGFVQRWDVVLL-GGLMGSVFSTLQFFVSPYIGSLSDTYGRKIL-LITMIGNILSALVWSYMLSRVIGGLSEGNVQLAIAILSDITTPANRGKALAHVGIAFAICFCIGPPIGAYFASNVYAAPALTLVLLLAETAF--LKMHFLFLGLFSGVEFTLTFLTFDLFDWNNTQNGKLIGSIGIVSALLQGGYVRRGVSSCAVGLVCLAAAVCMAFTSATVVNSLTAHASLKGKALGQF--RSSGQLGRAIGPLLACASYWTFG Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ALVFVFVLMDVLG-FALVLPLLPYLVSEL----------------LV-GTLLT-ANAAAQLVGAPLLGSMSDTIGRRVL-IFAACWTCISFALLMALVSRVLDGLLGGDVSLALAYVSDITTEENRARGLGAVGAAFGLAFILGPVIGGVLVSYSLMAPALASAIAAANALG--L-----YSFMFIAWEAMFATHYKSVYELPARTVSCILGLVALMYAAVQGGAIAAVSLAAMGAALGLWAMAIFGLASGVANTLLNALISVFGSALTLS--SALGSLVRVLAPSVVALSFQLTG Treme1 RTVFFSLVLDLLA-FTLPLPLFPRLIAWYALLSKLLHLSRNWDVVLL-GGAMGSLFSLCQCIISPWL-------GARVL-LATMLGNLLSAIIWTFLLSRLVGGLSEGNVQLSTAIISDVTTSSTRSKSLALVGIAFSICFTLGPSLGAYFASNIYATPAISLGLLLLETTY--LRLHGLFLLFFSGAEFTLTFLTYDLFSASNAENGRLLS----------SRHVRPGIASCFTGLGLLAGATCLAYTSATVVTGLTAAAAARGRALGRF--RSKGQLGRAIGPLLASSIYWTLG Trire2 RVVIVSLLLDLIS-FTFILPLFPKLLEFYTFLQQVLGGLSRYDIVLL-GGALGSLFSLLQAIASPMIGHFSDRYGRRAL-LASMCGNMLSVLLWTFVASRVVGGLSEGNVQIATAMASDISDETTRGSTMAIIGACFSVAFTFGPGLGAWLSTNPFAVAAFSLFLVAVETLY--LATHFVFLLFFSGMETSLSFMTYDLFQFTSAKNGRLLGYIGLVASIFQGGVTRRGTVACLTAFILLSAATCLAVTSATVVTGLNALSSFRGGKLGIM--RSWGQLGRGLGPILFTSVYWWAG Umbra1 RVVFTALLLDILA-FTVILPLLPRLLQFYTILGRLLAVVDKWDLVLL-GGFVGSLFSFLQFLVSPYIGKISDSIGRRTL-LLTMIGNLISTVLWAFLWARIVGGLSEGNVQLSIAIISDVTDDQNRSKGLALVGIAFAIAFTIGPALGAYFASYPFSSPAVALVLLSVEVLY--IAIHAFHLFIFSGMEFTLVFLTFDIFDYTNMQQGRLLGFIGIMSSLIQGGYVRRGVVACTLGLLMFTGAFFFAVTSGTVVSCLTSLASMKGQALGVF--RSRGQLGRAFGPLVACGVYWAYG Ustma22 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3360.fasta_al_trimmed; alignment length = 120] Allma1 ------------------------------------------------------------------------------------------------------------------------ Ashgo11 AI-NVYSAPEVHTAIEESLPAVFSRYKQDFRLLDTRLLLGYLTAITAAVSFVLDRKWDDVLALVGLYVVFSSAFWLFSRYGERHAVYQG--QQRITVRMQPEPSLVTLAAPGVFSADGHL Aspfu1 KV-PVYSINDLKSTTDDALVPYLCTFKQDHSKSNVRFLLGYSAVAIAAFTFYADRKWEATTAAVCSYFILNTGLTFWIWAVEAGEVFRGKRESTISIRSSVKKYKLRVPFMNWFSADGTF Aurde31 KV-NNASANEMKIACDDALKRFLAQFKMINLHTDVRLVLGWSSVIVAGLTGLYGWKFEKSKAGVILYMILSSVQTLYAYFIEQNIVFEGKRKTRITLRSRTIPYELDVAYTGFFDANGTM Batde5 VV-NPFVANELRHATADAVKQILVDFVEDHTISNVQLILGYVSSISIIAGSLYNFLFHQSMVSMAIYVVLNTALSAYNLLFAKDIMFVGVRKDHLVIRSKFEKYLLKFPYSAWFDVDGKL Botbo1 KV-NNASVTDLKNACDDALKRVLDRFKQQHRHIDVRLGLGYANTVIAVGSSLYGWKFETAKVGVILYVLLSAAQTLYTWFIEKDTVYVGKRKTRITIASRTVPYSLTLSYSAFFEDDGTL Botci1 ------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------ Canalb1 KT-NLNSVNDLRQTTDDHLGLVFQQYNESFTLIDLKLGLGLSTVVIAGLLFLVDKKWKDSYIACVLYGIISGVLYLINFFN-KNVKYIGYDNKKLSVATSSNKYNVTIGFNKFFDVVGFF Cangl SI-NVYSTSEAQKALDELLPSVFARYREDHTALDIKLALGYTMAAIAVGSFLLDKKKKEIMILTVLYFALSLVYWVYQKTVNKNAIYHGKKTSNIKVITSIGKYKVTVPITEVFTEKGFL Capow ------------------------------------------------------------------------------------------------------------------------ Catan2 ------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------ CocheC53 KI-AVHSLPDLKSTTDDALPNYLNSFKQIHTSTDIRLVLGYTAVTIAGALFYYDWKWEASKPAVVAYFVLNSIFTYWLWFVEKGLVYEGEGKTKLRISSWTKKYECDVPMTRWFTEDGYF Coere1 VV-NTSSISELRTACDTGLREFLKAYEEMHTHTDVKLVLGYIGVLFCAIDFAYSWKFSQTKISVSVYAVASVLALVYSYAVQRDTFFVGYNKAVVSAGSRAKQYRLTLPFTTWFYDDGEF Conco1 PV-DHYNIKELKTAMTEGIARYFNSLTEDHTFIDRHLILGYLGAIIAGATFYYSWGFQEHRVASVIYFILTGLMMFQAYFIQGDIVYLNKPKPAFKVKGNAFLYTLTINLAEVFDDKGRL Conpu1 KI-NNMNQTDLKNACDDALKRYLSRFKQIYLHTDVRLALGWAGVFVAVATGVYGYKFETAKAGFLLYLLLTGLQTAYAYFVEGDVVFVGKRKTRITISSRTLPYELAVSYASFFDAKGVM Copci KV-NNANLTELKNACDDAVKRFLARFKQIHLHTDVRLALGWLSVFVAAGTAFYGYKFETSKVGLIVYILLTTLSTLYAYFIEGDTIFVGKRKTRITLSSTTLPYSVSIPYAKFFDEKGVL Croqu1 KV-NNASIAELKNALDDSIKICLTKFTEDHTHDDVKLILGWASCLLAGGVSLAGWYWEKTQYFVGLYAVLSGILTAYVTMVQKQIIYVGTRESRITVSTQVSSYKLSVHFKQFFDVEGTL CryneH991 TV-NNANVAEIKSALDDIVKKYLLDFTPSLLHPTVHLVLGYASVVLALSSVVYSLRFDDSKAAVVGYCVLQTALWGWKRWVEKDEVFRGKRRRHLQVVTSSALYAVQLGVGELVDADGGV Crypa2 KI-TLYNLADLKNTSDDALPNYLNSFNQSHTLTDVRLGLGYSAFLLSAACFLWDYKFENTKAAVVVYSILNLALTLWIWLKEANVVYVGTAPSTIEIATSAKKYNLTISFTEWFDEKGHF Debha1 KT-NLNSIVQLRATCDDNLHASLSEYTQSFSLIDTKLALGYLTVVIAGLLYVVDKKFEKTYLSVILYFLISGILFYLTSTKKKNVKYIGYDDSKILVATWTNKYHLKIEFMKVFDAFGYY Dekbr2 ------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------ Falba KV-EPYALHDMKSAVDTFIADFLEKFSEKSQRGDRRMAISIITCLLAIGAAAYSHFFRSDTLASGLFVATVLFVWVYTRIEVGSVIFSGFKTDSVKVSSSVAPITLSFDLANYFDAKGAL Fomme1 KV-NNMNATDLKNACDDAVKRLLSQFKEKHTHTDVKLLLGWASVFTAVGTALYGWKFEQAKIGVILYVILTSASTLYSFFIEKDTVFVGRRRTHITVSARTLPYRASVPYNEFFDEEGTM Fusgr1 KV-PVYNLADLKNTSNDAIPNYLNSFEQSHTLTDVRLALGFSAFGIAAACFAWDYKHDTTKAAVVLYTLINTVMTLWIMFKEKDTIYEGTSPSKISIASSTKKYNLTIPFSEWFDQTGQF Galma1 KL-NNANATELKNACDDAIKRYLSRFKQSHLHTDVRLGLGWLSVFVAAGAALYGYKFEKSKIGLVVYIFLTMVQTLYAYFIEGNTIFVGKRKTRIHLTSMTLPYQLAVSYSSFFDEQGTM Ganpr1 KL-IPNNPADLRLTLDDSIRGILLEFREDNTHADRKLVTGYLACFIAALAGAYSTLFQETRVSVISFFILYVGFQWYMLYVEQNTIFVGEQRDYLHISSENERYKLVLDIPNYFDAEGRF Gloin1 IV-NNSNLIDLKNACDDYIQKFFVSFRQNNTHTDVKLVLGYLACAFALSGGYYGHIFNEAKICIIAYFVLNTLLILYSFIYEKEIIFVGSCVETITIQTNTKRYNIIFSFGNWFDVKGVM Hisca1 KV-PVYSLSDLKNTTDDAITPYLISFTADNFKSNVRLTLGYVAVAIAGALFYVDRRWEVSTASVISYFILNIAFTIWLWLVEAGQVFEGGTDGKLRIRSSTKKYTLRIPFSRWFSADGMF Klula1 PI-NVYAVPEVRKALDEALPEIFSRYTQTFKLIDTKLILGYSLVVFAAASFLLDKKWEQSKVLVALYMILSAVQLWFNKFVEKGTVYQGVKKN-VSVGAKYKKFHVSI--TKFFNEQGYM Lacbi2 KV-NNASFTELKNACDDAVKRYLSRFKQIHLHTDIRLGLGWLSVFVAAGTALYGYKFEKSKIGLVLYMVLTALSTLYAYFIEGETVFVGKRKTRISLSSHTEPYQLALGYNEFFDEQGTM Lenti61 KV-NNASPTDMKHACDDALKRFLSRFKQIHTHTDVRLALGWLSVLIAGGTGLYGWRFEQSKAGVLLYVFLTLAQTLYSYFIEGDIVFVGKRKTRITITSRTTPYALGLPYTDFFDEHGVM Malgl1 ------------------------------------------------------------------------------------------------------------------------ Mellp23 KV-NNGSITELKNALDDSTKVHLTKFIEDHSHDDIKLTLGWVSSLLAGAVSFAGWHWEKTQYVVVVYWIIATIALVHATFVQKQIIYVGRRASRITISTESTSYKVNLHYKDFFDVDGTL Mnele ------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------ Morel2 KV-DKSSLLDLKSACDDALKEYLETYKQSHKHTDIKLVLGYLGCAFAAAGSYYGYIFELPAVSVVLYYLFNVLMMAYAYLVEKNTIFTGYKSTTISIGSSVKSYDIDLAFQYWFDEDGVL Mucci2 QVSNKYDSTQIKNAVDDELSRYFSEFVQSHIHTDIKLLLGYVSCFIAGGSFLYEYKFNDALVCVVIYWVIQAISFAYGYLVEKDELFIGTKKVTLKISGKIDKYQLCLNVTTWFDTKGVL Mydma ------------------------------------------------------------------------------------------------------------------------ Neucr2 KI-TVYNVADLRATTDDALVNYLNSLVQSHTLLDTRLALGFSAFLLSAACFAWDYKFESTKIAVILYTLLNGALTYWIMFVERGTIYVGSTKDRVRLISDSKKYKLRVKFSEWFDASGRF Orpsp11 ------------------------------------------------------------------------------------------------------------------------ Pench1 KV-PVYSTNDLKSTSDDALLPYLTNFTPDYSKTNIRFLLGYSAVAIAGFTFYADRTWEATTAAVGTYFVLNSILTYWIWAVEAGEVYSGKRKTMISVSSSAKKYKLHVPFTTWFSADGVF Phybl2 QI-NKNDSVQAKNALDDEISKYFG-FKELHTHTDVKLVLGYLSCAIAGGAFLYEYKFQEAQLCVIAFWVLQFGISIYSATVEKGVVFSGKNE-TILVKTTMEPYKLELSIASWITTKGIV Picst3 KV-NLNSVADLRQNTDDNLPAALEGYEESFKLVDTKIALGLLTVAIAGGLFAIDKKFKESYAALAVYFVISLVMLVVNNQN-KNVKYIGYSSKKITIAAWTTKYHVKVPFAKFFDLTGYF Plicr1 RV-NNANLTELKNACDDAVKRHLSRFNQIHAHTDVRLALGWAGVFTAAATGLYGWKFEQSKAGLILYVVLTVLQTLYAYFVEGDIVFVGKRKTRITLSSHTHHYEVTIGYNAFFDSAGVM Polpo ------------------------------------------------------------------------------------------------------------------------ Pucgr2 QV-NNACITELKNALDDTMKSYLTSFTQDYFCDDVKLGLGWTSNIIAAGISLAGWHWEKTQYCVGAYMVLSLALTVFTSTVEKKKVFVGTKPSKVTISTEVKPYQLQLHFKEFFDVDGIL Punst1 KV-NNANLTELKNACDDALKRFLSRFKQIHTHTDVRLALGWGSVFTAAATGYYGWKFEKSKAGVILYVVLSAIQTLYAYFIERDIVFVGRRKTRITV------YTVSLPFAEWFDEKGVM Rhior3 ELANKYDATQLKNAVDDEIARYYGKFVQSHVHTDMKLFLGYVSCIIAGGSFYYEYTFRESIISVIVFWILQSIAFAYSHFIEKNEIFMGTQYSTLRISGKMEKYPLTLNVATWFTTKGTL Rhoto1 KV-NNASLTELKIALDDVVKEYFCLFTRSHAHEDVRLALGWTSVAVAAATGYYGYVFHESKVGVVLYVVLNTVLALYVAYVEKNVIFVGKRRTRLTISSLAFSYSLTLSFGEMVDSEGRV Rozal11 KI-NPYSLKTVKPLLDDHLAKYMVDVQESSKRAIVKLCLGYAMAIIAASVALYSYTFQTTIVGVAMYYFLNLIYFLYGKFYDRHAVIRGTINQHFEINSKTVTYVIDCFVETFFDPVGNF Sacce1 PI-NVYSIPELNQALDEALPSVFARYERSYALLDAKLYIGYSIAVVAGLSFFLDKKRDQIVLLVGAYFVLSLLFWYFSRFIEKGTVYVG-KRREIYVKTKFEKYLVELEVNKVFNESGYL Salro ------------------------------------------------------------------------------------------------------------------------ Schco3 KV-NNASTTELKNACDDTVKRYLSRFKQIHTHTDVRLGLGWLSVLVAGGTALYGYKFEQSKAGLILYCILTTLQTLYAFFVEGNVVFVGKRKSKITLSSRT--YELSVGYNTFFDASGVM Schpo1 -M-PKYNVSDFKSKFDKELTNHFNKYKQSFVFEDIRLLIAIACIIPAGLAFGIEYVFGVLKYLLPLYFLASCLLTFWSSVVKGSTVYVATKKEHIKISADTFLITTKFPVAHIFEEDGQI Sorma KI-TVYNVADLRATTDDALLNYLNSLVQSHTLLDTRLALGFSAFLLSAACFAWDYKFESTKVAVALYTLLNGALTYWIMFVERGTIYAGSTKDKIRVISDSKKYKLRIKFSEWFDASGRF Sphar ------------------------------------------------------------------------------------------------------------------------ Spipu1 VL-PNNNGSELKHTLDDCVRRILVLFKEIHTHTDRRLLLGYAACAFAAYASAYSYIFPDCKVCVVAYFILNGAMMLYATYIEKDIIFQGVKKDKITVRANYKRYTVTF--GDYYDVEGRL Sporo1 KI-NPLSLLELKTALDDTVREFFSLFRVSNSHQDIRLSLGWTSVFVALGTTWYAYQFQATKAGVSLYVVLNTILVLYVAYFEKNTIWVGKRRTILEISSEAIAYSLTLHVGELFDEEGRL Stehi1 KV-NNANLTELKNACDDALKRFLARFQQIHTHTDVRLALGWAGVFVAAGTAFYGYKFEESKVGLIVYMVLTTLQALYAYFIEGEIIFVGKRKTRITISSRTTPYTLNLEYARFFDEEGVL Tapde11 MV-NIFSLTELKNASDDTIPATLRKYTQSHTLMDVRLLLGYIGVVAAALAGGYDYKFEKAKIGVLTYFLFYGGMNAWQYFVERGTVYVGTKGARVVIRTRTDSYRVEVLFTKWFDLDGNL Thetr ------------------------------------------------------------------------------------------------------------------------ Treme1 ------------------------------------------------------------------------------------------------------------------------ Trire2 KV-SLYNLADLKNTADDAIPNYLNSFKQTHFLSDVRLVLGYSAFLVSAACFAWDYKFESTKIAVAVYTLLNGLLTFWMMFVEKGVVYQGVAPSKITVATSTKKYRLSIPFASFFDESGYF Umbra1 KI-NKYDSTQLKHTVDDHLRKYLTSYVENHQHMDVKLSLGYLSCLFAAAATYYEWKFQKAKICVASYFVINFIAWVYAYFIEKQDVFVGTKD-TLKISARLARYTLDFSFGKWFNEDGVL Ustma22 VV-DNSNLTELKATCDEAVERILSRFKVSHFHTDLRLVLGFVASAIMIGTSIWAYFWKRNKIAVVIYILLSGIQMVDS-YLQGNLIFSGTRKTSLTIASPPLPYTLQIHLGEWFTEDGEF Walse1 II-NPLDIVAAKHTCDDAVKKILTTYKQSFKHTDIQLIFGWIACIVAGGVCGWSYTFEESKLAVALYAVLSGLLYLHSRFIISNKIFTGKRKTSVQIRSTTIPYEVKLPYPDLFNSEGEF Zygro1 PI-NIYSIPELRQTLDEALPGIFSRFNQSFRLIDSQLVIGYGIALVAAASFLLDKKFEEVLILVGSYMVLSTVYWYFTKFVQKGITYEGVNKKSIAVKTFFENYHITFPVNKVFNEHGYL [Cluster3363.fasta_al_trimmed; alignment length = 168] Allma1 ELPTLGKQCSRADCAQLDFLPIQCTHCRQPFCKDHVQP-DDHACQCGVATCTTCAQCQGQFCLAHRHAQHACVLLQKHFPGSSATPRPVPKKKLPILE-LMKLKQKA-AKTPPAQRSYHAV-YFPKSASVGRVLD---TAFALTGMN-WKSATHDVFLV-VSDGATVV Ashgo11 GMLDVGKHCQ--YCRQIDFLPFHCTLCNSDFCSVHRTQ-EAHHC-------------------AVRVK--QETRNSTNALDKRKNMNL--SASNKVIQ-VAKIKRTAKDKIPHPNRVYIWC-FINRQWPLGRVLDYLSHHMDVKNVNLSAHSGEKLYLYKIEEGDALY Aspfu1 DLESIGRHCQFEYCHQLDFLPFRCESCRGTFCLEHRTE-TAHRCQCAHLDCKTCPDCNRQYCLRHRLREHECTETIRSMFARLAP-----SAAARISE-LNALKKAAKAGIPADKRLYLHV-WFDSRWKVGRVLDDAARRLRIENVN-NRAEEERLRIFHVKQGHTIV Aurde31 SLVDVGSRCS--SCGTVDFLPIRCAICTREYCGNDI---HGHPCRCAFQPCDRCPACARAFCAYHREPSHQCVAEARAILRKTQKPITDPLRRLEALE-VMKLRHRAKTNVPQQNRIHVRV-WFKKSVSTGRAVDLCATLFNINRTG-ELAPSALVRLPNVSDGTNLI Batde5 --MNYGLNCSLALCNKLDFLPFVCQTCQCAYCPAHRFP-DTHGCSCSFDGC--CPSCTNKFCLAHRHKSHNCPARIKAFVSQANSKKLNP-----AVS-LIKLKMHATTKILPENRVYLLC-FYHSNTVIGRLLDLVASKANVKNTN-NIAPP--LGLFHLSQGQCIV Botbo1 DLAPIGAHCSRPLCNDLDLLPIQCPHCRALFCRHHISQ-ESHACVCTVQGCTKCSKCNGSFCVEHRYPAHECIPAAHALLAKSTKVPTDPRARFRALE-LMKLRGRAVSGAPPDQRLYVRA-WFRKTTSVGRTLDLLTAQLKIY-------SVWYFDLAHSS------ Botci1 DPTLIGVHCQYEYCNQLDFLPFRCESCRGTFCLDHRTE-SSHHC-CASPNC-A------------RFN-----TSAKLAFGKVASTRVLPSAAARLVA-VNQLKKTAKAKIPPEKRVYINV-FYSKDWVMGRVLDAAAKALQVENVN-NQGEKEKLRIFHLVSGNRIV Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 GLIDIGKNCQ--YCNQLDFLPFICEFCKKTFCSQHRTI-EQHQC-------------------ADKRKEAKLNSGSSNAFKKKKSGTTNGSSNNKFID-IANLKKNAKNKIIMNDRIYIWC-FISKNWVVGRSLDSVADNLHIQNKN-NVTSSEKLNIFKFKTGDTIY Cangl GMLDVGTHCQ--YCRQLDFLPFHCKLCDGDFCSEHRSK-ESHHC-------------------HIRVKPSSTT--NPAALNKPKTKKKV-TSSNRLVE-LSTLKKTAKSKIPVQNRIYIYC-YINKIWPVGRALDYLSQQLHVTNVNGNVDKGEKLFLYKVKDLDTLY Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 EFHDLGDTCSHADCGLHDFLPITCASCQHTFCKDHAAF-DAHSCACAVTDCAA----------------------QRIFPAAPPPSKPKPKKKLPILE-IMKLKQTA-ASIPSQDR-------------IGRALD---TAFQATGKS-WDAVSHTIILLNVENGVPLV Cioin SEFDIGKHCSYDECSRLDFLPFTCDVCANIFCKDHEKP-AEHKCECTFLNCHKCSACFEQFCLNHRSQDHKCEDVKKLIVLQAKSEKLAA-----KVQ-VMKLKQKAVNDIPQEHRIYFSISYHWK---VGKMLDYCCDNMNIVNKN-N--CDEKLKLCSLFNGSNIV CocheC53 EVEAIGAHCQMEYCNVLDFLPFPCESCKGTFCLDHRTE-TAHKC-CASISCKTCTRCNRRYCLKHRFEDHDCKVRTQTALSKDEKRRAAPAASSAQAE-LNALKRTAKASVPQEKRIYLHV-FYNKEWTVGRVLDMAAKALQVQNVN-NRGEEEKLRVFHCQSGNMIV Coere1 ELPHIGKCCTKKGCQQLDFLPVICKHCRHVFCSLHASI-TEHSC--------------SFYTKPSRDANHSSKTEQIQALTT-HKVRISP-----KIE-LMRLKARATGSIDVVDRFYLSV-YINRNALVGSSAMQFARNLHL-----STLNIYRLKPLNLFNGCSLE Conco1 ELSHIGDNCQSTICKQLDFLPFYCTTCELTFCQEHFIS-NEHPCPCNYQNC--CKYCKNFYCVSHRSFDHKCEEETLSKIQKTAVKKQSP-----LVK-LMLIKQKAKTSIQPPNRFYFNLSYVHSDWIIGKLIDKLSSSNNVT--N-NRLDKEMINLFNFKQGNTLI Conpu1 DPASVGTHCSVPSCNTLDFLPIRC-RCDRNFCTIHAPA-DVHQCRCAAPSCNKSNSCRLSFCVDHRHPTHSCSEKEVSIHVKSSKLSSDPAAMIRKVA-LMKLRHRAVSTVPLDQRLHVTL-WFRK-------------------------EPQ-------------- Copci DLPQIGAHCALETCNVCDFLPITC-KCQKKFCRDHIFP-DNHGCRCTLEGCQKCEKCHGSFCVQHRYPTHNCAALLKKNFGS-KKPPTDPLAQWKKVE-LMKLRHRAVTSPPVDQRLAVSV-WLRKSVSGGKAIDMLSTQMKVR-------NSTLTKLYKVDDGDTLV Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Crypa2 DATLVGSHCEADYCNLLDFLPFLCQSCNKTFCLDHRTE-SAHRC-CAAPDCKTCDRCNRDYCLKHRFEDHDCKKAFNTAFSNAAAGRALPSASQRVVA-VNDLKKTAKDKLAAEKRVYLYV-FYSKDWVIGRVLDAAAKSLQIENIN-NQSEEDKLRVFHLTSGNTIV Debha1 GIMNIGKQCH--KCQQVDFLPFHCEYCNFTYCSKHRNL-ESHQC-------------------KDKLKENSIN-------AKKKSDN---QARSKVAE-MAILRREAKTKVGDTDKIYLWC-WVSKQWSVGRALDSIADNLNIVNIN-NRTSDERLCICKLKNADVIY Dekbr2 GMLDIGKHCC--ICRRLDFLPYTCPKCSMSFCNEHRKQFNEHKC-------------------KMRRDNTKSQ--VESALFRSSSGRLH-SSTQRLVS-LARLKKAAKNRVSSSQRIYVHC-FCSKAWPVGRMLDSFSDLMSIKNVN-NMSESQKSTVFRIQDLDTVY Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ETLDIGTKCL--GCGLMDFLPIKCSYCHNPFCNKCI---KTHQCICNL--CGKCAGCHKNYCVEHRNQTHHCVSLTNFVLEKQKSYPTQP---------TLSAQKKAFKTVPFNCRLYFEV-WINKNWTCGKVIDVICTEFGLPNTN----NSPKYGLVDLTNFSTIM Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 DPPTIGSGCSHTECHNHDFLPIKCPTCNKLYCSDHYFQ-DAHECPCSFEGCTKCSRCSLAFCSIHRFPSHACKEAARALLAKSSQPPTGPSQASKTVQ-LMKMRQTAVGQVPPTERHHVQA-WFRKSVSTGRAFDLLQQRLQ---------PVKTWTLYKFEDGCKLL Fusgr1 EATLIGKHCEYDYCNQLDFLPFFCQSCRKTFCLDHRTE-TAHVC-CSSPECKTCQTCNRDYCLKHRLKDHDCSQKTRSAFDK--AGRALPSASARIVA-VNNLKKTAKAKTPIEKRVYIYV-FYNKDWVVGRVLDAAARSLQVQNIN-NQSEKDKLRVFHLQSGNTVV Galma1 DLPQIGAHCSLASCNALDFLPITC-QCNKSFCFEHITP-DHHECRCLVEGCQKCPACHQSFCVEHRHRTHRCSV--ETTFSSTTKRPTDPLVQWQKME-VMKMRHRAMTSLSPDQRLHVKV-WFRKTVVTGRALDLLVTQLSLG-------SNQAVKMSKVEDGCSLI Ganpr1 ELPSLGRNCAFSTCARLDFLPFTCTLCSLSFCSDHRLP-PSHSCMCCIAGCTTCDHCGLVYCLKHRHASHSCVAEIQEKLAKPKAKY-NP-----KIE-LMKLKMKAQASVPTDRRFYLRV-FFDKDCLPGKLVDRLASTYKVTN-T-NASDTKRLRLFNVESGGRVA Gloin1 EFPNIGENCSFKGCSQLDFLPFWCGSCGKKYCLDHRYP-NSHECKCFITECKNCDGCGEAFCLKHRHPAHQCEVKAEELISKSSSKN---------VT-TNKPKKKNKSTIPVNARVYLSV-FFNKEWTIGKVLDKVATVGKITNNN-NKLDPNRLILVNVESGDDIY Hisca1 DLESIGKHCQFSYCNQLDFLPFRCESCKGTFCLDHRTE-TAHKCQCSHPSCKTCNECNRQYCLKHRLRDHDCAEKARLAFSRVAS-NLTPTAAARMAM-LAELKKKAKPNLALPKRFYLHV-YFDSAWSVGKVLDDAARRLQVQNVN-NRVEAERLRVFHVAQGDTIV Klula1 GMLDVGTHCS--FCRQTDFLPFHCSACNGDFCANHRLK-EDHHC-------------------PDRIK-QEDNSSSRVAIDKKSTTKF--SSANKLIQ-VTKMKRTAKDSIPVANRIYAWC-FINKMWPIGRALDSLASVLNVKNSNIDHSTDEKLFLYKIQEGDTLY Lacbi2 DLLQIGAHCSLPSCNDLDFLPIVC-NCNKHFCRFHSAP-DRHSCRCIVESCNKCLQCLQAFCPDHRYPSHTCSA--RAIFAK-TKISTNPLAQLHKVE-LIKLRRRALVSVPSDQRLHIKV-WFRKTLIAGKVLDLIATQLHFS-------DSTPIDLCKVEDPCTLL Lenti61 GLPSIGAHCSLPSCNLNDFLPIRC-QCQLLFCRDHIAP-DVHNCRCAAEGCNKCSGCSQAYCAQHREPSHACTAAAKALLAKLTTKPSNPEEQQRKIA-AMKMRHKAQASVSMDQRLYLKV-WFRKTIITGRALDLLAAHFKMT-------DTQPLRLILIPDGSSLT Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 EFPSVGAHCDAPSCQSLDFLPYRCTFCQHTFCSPHRLP-ADHACLCALPKCNRCPDCSQTFCLPHRQPDHNCPEAAKAAIAEAAAAPAPPKAS-RVVT-VMKIKKNAVDKIPISSRIYVYI-YVDKTWTVGRSMDKIVEWLKIAVPK-N--AQKRFSIFHVESGDVFF Mucci2 ELPQIGKNCQLDGCNSLDFLPVACPLCHQTFCGDHRLP-SNHKCQCTVKGCRDCNGCDQDFCLKHRHPSHSCQLAAQEKVAKVRSKNGG------MVE-LMKIKSQAKPSVPAASRIYIYV-YFDKKNSVGKALDLIADICKVNNKN-NTLDPERLELYKLKNLDTVL Mydma AELNIGAHCSFKECNQIDFLPIKCQKCDLMFCKLHSVD-YQHLCKCSIDDCLVCDRCNQQTCLRHRLPDHSCQQIKSDGIELKHNLKTHPSKTLTKVM-QMKMKMNSIESVPLSERIYLNV-FFSKELSMGRILDLSAQQFDLKNQN----FSKKLIFCTLNEFGDII Neucr2 DASLVGKHCQLEYCNQLDFLPFLCQSCHKTFCLDHRSE-SSHNC-CADDACKTCPSCNRDYCLKHRLADHDCKASAKSALER--AARSLPTAAQRVIA-VNTLKKTAKDKIPPEKRIYLYV-FYNKEWVVGRVLDAAARRLQVQNIN-NQSEEDRLRVFHLVNGNTIV Orpsp11 --------------------------------------------KCDFENC--CRKCHKNYCLKHRHPDHKCTQEIKNIINTKKAKKLNP-----KIE-LIKMKAKAKAGVPMKCRKYFRI----------------------------------------------- Pench1 DLESLGRHCQYEYCGQLDFLPFRCESCHSTYCLDHRTE-TAHQCQCAHTQCKTCPQCHHQYCLKHRLREHECADTIKSMFARAAKGTLLPSPAARAVA-VNGLKRSAKASVPVDKRLYLHT-FFDSRWKVGRVLDDAAKKLRVQNLN-NRVEDSRLRIFHTQPD---- Phybl2 ELPNIGQHCTLAHCKALDFLPIICPLCQHAFCNDHRLP-LDHSCPCAVKGCKDCDGCDKGYCLRHRHPTHGCAAAAQAQIGKAVQKKGSL-----LVE-KMKIKAKAKTSVPLNMRIYIFV-FFDKTHRVGRLLDMIADAFQIKNAN-NRLDDQRLELVNLSDLDTVL Picst3 GIIDIGKNCA--KCSQLDFLPFHCEFCNLTFCSNHRTL-ESHNC-------------------ERRRTNQRLQKKTPNAFSKSAASSL--SATSRTVE-LGKLRKDAKAKIPANDRIYIWS-FVSKNWVVGRALDSIADNLKIPNIN-NSTSEEKLNIFKFKNGDIIY Plicr1 DLPAIGSHCALASCNELDLLPIRC-RCDKFFCRHHSFP-DAHNCRCALDKCNKCSRCNLSFCVDHRYPAHSCTAAAQALLAKAQT-PTDPLAQQKKIL-LMKTRHRAVAAVTVDRRLHLKV-WFRKSVGTGRALDSMATQLKIS-------DASPLYMCSLEDGATIV Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------MCNITNRN-NMIDPERLYLYKVKDLDTIL Rhoto1 PPAELGAHCSLPSCNAFDFLPIVCPHCSASFCGRHASP-SSHACEA---------------------------EGQQAALAKPSAPAKKP---NPTLE-LMRLKGRAVGDVPMPDRLFLKV-WVSKIITAGKALDLFADLFKVTNDN-N-ADPSKLLSLGVANG-GTV Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 GMLDVGKHCA--YCRQLDFLPFHCSFCNEDFCSNHRLK-EDHHC-------------------SVRIQ-RVSE--NSKTLDKNKSKKNF-SSSNKIIQ-LANLKKIAKPKIPMQNRIYIWC-YINKMWPVGRAMDYLSIQLNVTNSSSN----DKFQLCKIKDLDTLY Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 DLNPIGAHCTLSSCHELDLLPILCPHCSHQFCRAHFTP-DSHACRCAVDNCDKCAQCSGFYCAEHRHPSHRCSDAAKALLAKTKKLPTDPLAQYRKVE-AMKMRHKATTSAPLEERLHIYV-WVRKTMSTGRALDCFATLFSLS-------PHQLI----VQDASTLL Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma DASLIGKHCQLEYCNQLDFLPFLCQSCHKTFCLDHRSE-SSHNC-CADDACKTCTSCNRDYCLKHRLADHDCKASAKSALQR--AAKSLPTAAQRMIA-LNTLKKTAKEKISPEKRIYLFV-FYNKEWVVGRVLDAAARSLQVQNIN-NQSEEDRLRVFHLANGNTIV Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 MLPDVLNGASFE-MKLVRFI---------IDSLDHRHA-EAHECPCSFSSC--CPKCAKQFCLRHRHPDHSCTQAYKELIATKKSKKLNP-----TIE-LMKMKMHAKKPVPLESRVYFRI-FFHKDWTIGRLIDNIAAAVKIQNMN-NTGEDKKLNLFHLQSGQALI Sporo1 ------------------ML------------------------TAGV------------------HAQQKEDSKQEIALAAPSSTLNKAASKNPMIQ-LMKLKQRANGDG----------------VSGGKALDLFADLFKIPNSN-HLADASKRLSLAATDGKGTV Stehi1 DLPLIGAHCSLSSCNELDLLPIRC-LCDKQYCRKHFLP-DDHACRCASVNCKKCPRCNLAYCASHREPSHSCPEAAHALLTKPKKRPTDPLAQLQKIE-LMQMRHRAVDTILIDQRLHVKI-WFRKTIGVGKALDLLTAQLGKTT------PSDPTIWTHYRLQTRLM Tapde11 ---------------------------------EHLA------------------------------------SKSQDALGA--------AVLRTNVE-VGKLKAAAKVRTPVERRVYVHL-FIDAQWSVGRTLDAVASKAGLVNEN-ARTEGRRLHLLCVKSGDSIL Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Trire2 DASLVGKHCQYEYCNQLDFLPFFCQSCTKTFCLDHRSE-SAHKC-CASPECETCETCNRDYCLKHRFKDHNCKQRTKSALDR--AGRALPSAAARMVA-VNNLKKTAKDKLAPEKRVYVYV-FYSKDWVVGRLLDAAARSLQVQNVN-NQSERDKLRVFHIQSGNTLV Umbra1 EYPHLGSHCSFANCRELDFLPHPCPLCTNTYCGPHRFP-ATHDCPCSVEGCHECNACSSLFCLKHRYRAHQCSITARMKIEEVRPKRLNP-----KLE-LMKLKTRAKDGVPQESRLYFTV-FFDKTQSIGRMLDRIAQLGNISNNN-HKLDPNRLHLLTLNNGVDVM Ustma22 --MEIGTHCALSDCGRLSFLPISCPLCTTTFCESHFLP-GQHSCKTAFTHA--CERCKGLFCAAHRSASHGCS----------------P-----MTEGQMKIKAMQE-------------------------------AKNFPNRK-T------------------- Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Zygro1 GMLDVGTHCS--FCRQLDFLPFHCKLCNLDFCENHRTK-ESHHC-------------------YIRVQ--QQQ--SQGTLDKKSTAKK--SSSNKLVL-LTQLKKTAVQRIPVSNRIYIWC-YVNKIWPIGRVLDAIAQQFGVPNRNDNFKQEDKLSLYKISDLDTLY [Cluster3364.fasta_al_trimmed; alignment length = 295] Allma1 ----------------------------------------------------------------------------------------MLLHGP-PGTGKTCLAHALANKLAVRLYQHARYLIQLDAATLLSRFFGESPKQIHRVLSSVRAVARASSVLLVLLIDEVESIAGHRATAA-GDRDPADATRAVNALLTQLDKLRAVPNVLVLVTTNLPGAVDAVMDRMDLAQFLGPPPPLARYAILRSSVQELIRTGILLAQRVPN--ASGRRLRKLATSALNLGGLARAVRAESGD Ashgo11 YTVDCCLKLVRTVTRRLISFCIEKLYIEKFDINFETFQLVRPSREYEGAWEALYFDDD--IKGQLFNYATIALKMSTLSVNT-GGNRLLLVHGP-PGTGKTTICKALCHKLAIR--LHSVILVELACSKVFSRWFGESSKNIDTIFKDLEKLIKDGNQFVCLLIDEVETIAFSRSSLI-NKNETTDAIRVVNTLLTQLDNMKKYKNFLTLATSNLLDSMDAFIDRADGIFNVPTPSTQGCQNILELNISKLLTAGVIIVSRCADLRLSGRTMGKLPLKALSIVALASVI------ Aspfu1 LHVEARVKIRDEITQWLHAQALESILITELDVQAEDLGTTKPSTELDGLWESLQYDQP--LQSTLLRAITRMVSFSKLDKWTINWNRLILLWGP-PGTGKTSLCRGLSQKLAIRLGKHQSKLVEINAHSLGSKYFGESGKLVSKAFESIELLLEEEDSFVCVFVDEIETLAARRERAL-SSKEPFDAVRAVNALLTGLDRLKHHHNVIVICTSNLVTALDAFLDRVDIKQFVPHLSNKTIYGIYKECLEELSWRGIIAASASVG--LSGRTIRRLPALSLVLQALRRCITSEIQA Aurde31 VHIEVRLTVRQEVARFILGTMVDRILVTEMEIHIEDVMAANPNAAWEGLWETLVYDED--IKSRLLDYLYATLIFSNVDSNLISWNRVLLLHGP-PGTGKTSLARALAQKVSIRLASRRTTLLEINSHSLFSRWFSESGKLVQKLFATVNELADDDDCFVVVLIDEVESLTAARAGAM-SGSEPSDALRVVNALLTQLDKLKRRKNVLIISTSNLTKAIDAFMDRADIVQYIGLPSSDAIYEILRSCLLELMRTGIVMASRCTG--MSGRSLRRLPVLSHALDAMDRVIASHEHK Batde5 --MFICEY---------------HIDI--LDVHVDTVSTSKPCHELEGVWESLVFDDD--LPLQLLDYVYTSILFSNIDTNLINVNRVVLLHGP-PGSGKTTLCRALAQKLSIRLSDRFGKLVEINSHSLFSKFFSESSKLVIQLFQNLHEILNNQDAFVCILIDEVESLSAARKASA-AGLEPSDAIRVVNALLTQIDLLRQHKYVLVLATSNITEAIDAFIDRADIKQYIGDPSPRAIYQILSSCLVELMNKMLIVAYLCDG--MSGRALRKLPFLAHA-------------- Botbo1 VHIEVRLKLRKCIKQFILKQYVEAIYASELDIHIEDTSAATPSRGWEGLWDSLVYSDD--IKSRLLNYIYATLLLSGVDFNIVSWNRVVLLHGP-PGTGKTSLCRALAQKLSIRLSDRHAKLVEINSHSLFSRWFSESGKLVQRLFASVTEMVDDETTFVVVLIDEVESLTAARAGAM-AGTEPSDALRVVNALLTQLDKLKHRKNVLVMSTSNLPKAIDAYVDRADIVQYVGLPPPEAIYWILRSCINELIKTKVILAEQC--QGMSGRSLRRLPVLAHALHAMEKVVVETKRG Botci1 VIFDARLRTHKALSALIVALNIEALIPIEKPTHLPEIPSAEPHHDFDGSWEHEVFYNRR--------------------------------------TGKTTLCQAIAQRLAIRLIEQHTKLIQVKTATLLSKYYSESASQVDDLLTKIKTMCQINKRIIIVLIDEVESIAVSRHSGI-MHGEAQDSLRATNALLTGFDRVRACPNVVFMSTSNMVDCLDAFLDRCAIQIPFQPPSEESQYKILRASVLEL------AAKEKLG--ISGRFLTQIPDQALMLDCIKKFVEDLLSS Caeel IHAEIRICVQKRFSEFELNELFEKLVIGT--IHVESIIGSQPCVEFDSIWENLIYDSN--LKNEVMSYVAALARLSHVNTKIINVNRLILLTGP-PGTGKTSLCKGLAQHLSIRMNDKKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDELAEDEKCMVFVLIDEVESLGMCRESSS-SRSEPSDAIRAVNALLTQIDRIRRRDNVLILCTSNLESTLDALVDRADIVKNVGQPSDFARYSMLKSSIMELARIGVVIAQEARG--LSGRAISMLPTLVYSLEAVKERLSRNN-- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl VTVDACLRIKAIRNAIQLSLFVKVVYLNKFEIYFQTQSIAHPCPELEGVWENLYYNKD--IKIKLLNYSTASLRLAVVNEMISANNKMILLHGP-PGTGKTTLCKALCNKLAIRMAKTGSLLYELSCSRVFSRWFGESSKNITQLFRDIEADIITANNFVFLLIDEVETIATSRINLS-NKNEASDSVRVVNSLLTHLDKLKRYPNFLVLATSNLLETLDAFVDRADGVFFIGNPTSKELKYMINSSIDKLIKTGVILATFCE--------------VCIKCCSYI--------- Capow --------LRERILSYLLQNNVEFISISDLMLHLQEDASCMPNREFHGIWESLVFDQNGQVQSRLLQYATTAMLFSNVNSNVVSWNRVILLHGP-PGSGKTSLCKALAQKLAIRLSGRQGRFIEINSHNLFSKYFSESGKLVGRLFARIRQVVRDERTLVCLLIDEVESITAARQSAS-TGADPSDALRVVNAVLTQIDSLRHNRNVLLMATSNLTKCIDAFLDRADIKMHVGYPSWRAVYTILFTAIQELMLRGIIAAKAAQG--ISGRTLKKLPLLAHAITALHNVAEDQHRT Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin IYVEVQQKIIQATEQCFFLKHVDNFKFLDMKFYVEELSAATPSKGFENLWESLIYDSN--IKEGLLNYTQSGLYFAGVDDKLITWNRVVLLHGP-PGTGKTSLCRALAHKLAIRLSDRESSLLEVNSHSLFSKWFSESGKLVMKMFQKVEGLASDPHHFVCLLIDEVESLTAARSSAS-AGTEPSDAIRVVNAVLTQLDRLKRYNNVLILTTSNVTGKIDAFVDRADIRFFIGFPSAEAVYSILRTCILELCRARVMISQECAG--MSGRALRKLPFLAHAFLALSNAVKIMQKE CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 VHVEVRLSIKSQVKGWLLASCVERIAVAELNIHTEGVLAASPSTSLEGLWDGLIYSDN--IKLRLLDYIHATLILSNVDSNLVSWNRVVLLHGP-PGTGKTSLCRALAQKLSIRMSHRQSRLLEINSHSLFSRWFSESGKLVQRLFNNINEMIEDEDCFVVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLRQKKNVLVMSTSNLAKAIDAFVDRADIVQYVDLPPREAIYEILRSSICEFVDKKLILSARCRELGLSGRALRRLPVLALALDAMGKVLDERAST Copci VHVEVRLQVRSNVRNYILASTVEQITICELQIHVDDTMAASPNRSWEGLWDSLVYSND--VKMKLLDYIHATLILSNVDFNLVSWNRVVLLHGP-PGTGKTSLCRALAQKLAIRFSHRNARLLEINSHSLFSKWFSESGKLVQRLFTSITDLVDEEDAFVVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLKHRKNVLVMATSNLVKAIDAFVDRADIIQYIDLPSREAVYDILRSSVSEIMSKGVILAAKCQAHGMSGRSLRRLPVLALAIAGMDKIVDEHGDE Croqu1 --VEVRLRVRESIGRYIIADEVDSVCCAELHIHIEGDVAAMPARRLEGIWESLIYEDG--VKTRLLNYIYSSVVFANVNQALIAWHRLLLLHGP-PGTGKTSLCRALAQKISIRLSGMKTELVEINSHSLFSKWFSESGKLVQSLFTKIGQAADDPDTFVMVLIDEVESLAGSRSTGT-SGNEPSDALRAVNALLTELDKLKHRRNVLVLTTSNITGSIDAFLDRADIKQYIGLPPPEAIYWILRTCLCELVKAEIVIAERATG--MSGRTLRRLPLLAHALNGMLMAVEDDKL- CryneH991 IHVEVRQKIMQIVTQFILRDHVERIWVEEIQVHVEKVSAASPSAELDGIWDTLVYSDD--IKARLLNYIYSTILFSDIDFNVIAWNRVILLHGP-PGTGKTSLCRALAQKMSIRLSQKHGKIIEINSHSLFSKWFSESGKLVQKLFQTVTEMVEDESGFVVVMIDEVESLTAARASAM-KGNDPSDSLRVVNALLTQLDKLRTRKNVLVVTTSNLVDAIDAFISRVDLLESVPLPPPRAIYSILSGCLKECITKKLIIAEKGKE----AREVRERGVAA--IEAMHKVVDVEQEK Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 LDIEVCLRLKVSLTFYLAEGCFKEISIGSMNFKLQPKLANAPDNKLIGSWEKLKMKGN--LKQSIYTNVQVLLTLSFAGELLTALDKLILLHGP-PGTGKSSLAKAIFQKFSVKAISSPILLLELAPDRIYSRYYGESPKKLSMLFSTIEATLKKEGGFIFMIIDEIESLATERSMLL-ANNETTDGVRMVNILLTHLDKLRHYKNFFMIGTSNLIESVDSFKDRANALYELPLPNEETIYSILEQQIIHFLDLGVLIAAYCSV---------SIPFCIHE-------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi IGIEIIVNLKSNIESFIPDKSIDYYKIILFQINYETSPPYQPNKSIETLWENLIYEDG--LKSKLLSYMSTLILFSRIDSNIVSNNKVIFLYGP-PGTGKTSLAKALAQRISIVYRDRFSQLIEINTHSLFSKWFSESGKLVMKMFENIKELLEDQNCFVMILIDEVESLAAARSSAINNGTEPSDSIRVVNAFLTQLDQLKQYSNVLVVATSNITKAVDAFIDRADIKQFIGPPPIDA---------------------------------RKIHLSNYI-------------- Dmel VHVEVCLRIRNNVETALTAEQTEHVHSVLFRFHFDSIVAASPAAQFVGLWENLIYETG--LKEKLLKFALSALMFSRVDTNVIACNRLILLHGP-PGTGKTSLCKALAQKLSIRTQGSYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVLIDEVESLAYARS-AM-SSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDAFVDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLLAERSVG--LSGRTLRKLPLLAHALDAMLEALEQHLGE Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 VHIEVRLVIRKLVHQYLLRDSVEKITVSELQIHVEEYTAGSPSNELEGLWESLFYDGD--VKSRLLNYIYATIGFSDVDHNLVSWNRVILLHGP-PGTGKTSLCRALAQKLSIRLKDRNTYLFEINSHSLFSRWFSESGKLVQNLFSTVTEMAKEEDDFVVLLIDEIESLTSARSNAL-SGNEPSDALRVVNALLTQIDRLKYQKNVLIMATSNLAKAIDAFIDRADVMQYIDYPPAIAIYDILRSCLLELMSKGVIIAEKCKG--MSGRSLRRLPVLAHALNAMKKVVDDETSN Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 VHIEVRLKIRNLVHSFVLASSVDKIVVCELQIYVDDTMAASPNRTYEGLWDSLIYAGD--IKMKLLDYIHATLVFSNVDFNLITWNRVVLLHGP-PGTGKTSLCRALAQKLAIRLSHRHARLLEINSHSLFSKWFSESGKLVQRLFTSITELVEEEDGFVVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLKQRKNVLIMATSNLVKAIDAFVDRADIVQYVDLPSREAIYEILRSCLCEIMLKGIILATECRGQGMSGRALRRLPVLALALDGMEKAVKHRASE Ganpr1 ------------------------LHL--MSVFVENVMTSHPSRTLEGLWESLVFDDE--IQTQLLDYITTTMEFSAVDPNIISWNRVVLLYGP-PGTGKTSLCRALAHKLSVRLSNRYGKLIEINSHSLFSKWFSESGKLVMKMFSTISELASDDDAFVTVLIDEVESLTAARRAAV-GGSEPSDAVRVVNALLTQIDQIKKRKNVLIVTTSNVTEAIDAFVDRADIKHYIAPPSARAVYTILCSCISELVRTGIVVADKCAALQLSGRTLRRLPFLAHAVEALEKALESEGIA Gloin1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 LHVEARIRVRDEVTKWLYCQYLDVIKVMELDVQAEEGPQARPSKELDGLWES------------------------KLNTWTINWNRLILLYGP-PGTGKTSLCRGLAQKLSIRLGKQQSKMVEINAHSLGSKFFSESGKLVARMFDNIENILEEEDTFVCVFIDEAETLIAKREQSV-HGNEPFDAMRAVNALLTALDRLRHRQNVVVLCTSNLITALDAFLDRVDIKQFMPNPSSRVIYEIFRSCLENLNHCGLIVAEASVG--LSGRSLRRLPALSLVVRALALGVEEEKRA Klula1 IFVDCEMNIQNALEAKLLSSYVKDVDLEIYEMNFKHLKEVKPSVKFDKQWEMLHYDSN--LKEKMYSHGISSLKLS------IRKNNLFLLHGP-PGTGKTTLCKSFCQKLALRNCNLSGILVEVSCSQIFSRWFGESTKNLDGIFNDIERLLKHEKKFVCLLFDEVESLAISRHQLL-NTNETTDSVRVLNCLMTHLDNLKKYPNFILLCTSNLRENIDAFLDRLDVSFYVGFPSVTVCQQILTNITQEMINSEIIFSNACK---ISGRTLSKVPLSCLSLLALNATLRKHHRQ Lacbi2 VHVEVRLKIRSLVSSYILSSSVERIVACELQIHVGDTMAASPNIGWEGLWDSLIYADD--IKLKLLDYIHATLVFSNVDFNLICWNRVVLLHGP-PGTGKTSLCRALAQKLSIRLSHRHARLLEINSHSLFSRWFSESGKLVQRLFNSITELVDDEDGFVVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLKHRKNVLIMSTSNLVKAIDAFVDRADIVQYVDLPSREAIYEILRTCVCEIMQKGIILAAQCRAQGMSGRALRRLPVIAMALDGMEAIVKDKAKE Lenti61 VHIEVRVSIRNAVHSYLLASSIERIAASELQIHVEQVMAASPSMSWEGLWESLIYSDD--IKSKLLDYIYATVVFSDVDFNVVSWNRVVLLHGP-PGTGKTSLCRALAQKLSIRLSHRHGRLLEINSHSLFSRWFSESGKLVQKLFSSIMEMVEDEETFVIVLIDEVESLTAARAGAM-AGTEPSDALRVVNALLTQLDKLKHKKNCLVMSTSNLATAIDAFVDRADIVQYVDLPPREAIYEILRGCLVELVKRGIVLAQKCRDQEMSGRSLRRLPVLAHALEAMERVVQSQATE Malgl1 VHVEVRLRIEAAVRRFILAEHVDRIYVGEMELHVDNAVAATPNHALDGLWRTLVYSDH--VKEHLLHYIYSTLEFSGIDFHVIAWNRVVLLHGP-PGTGKTSLCRALAQKLAIRLQKRHVKLVDINSHSLFSKWFSESGKLVHRLFDMVTELVEDEAGFVVVLIDEVESVTKARNSLV-AGTEPSDSIRVVNALLTELDKLKYRRNVLIMATSNLSDSIDAFLDRADIRQYIGLPGTEAGYSMLRACVLELIRVGLG--------------IRRHGCF----------------- Mellp23 MIVEVRLKARQSIGNYILEDEVDHVYCAELHIHIDGDVAASPAHRLEGIWESLIYEDG--LKIKLLNYIYSSIIFANVNQALIAWHRLILLHGP-PGTGKTSLCRSLSQKISIRLSYLKTELIEINSHSLFSKWFSESGKLVQSLFLKISEMLEDDDMFVIVLIDEVESLAGSRSTGT-SGNEPSDALRAVNALLTELDKLKHRRNVLILTTSNLTGSIGAFMDRADLKQYIGLPPIEAIYWILRTCLNELIKVGILISEKAKG--MSGRSLRRLPLLAHSLDGMLRSVIEDQLS Mnele VSVEVCQKLKSHCETNLLRAHVLHVQV--LHVHIENISTATPSVHFQGLWDNLIFDQD--VKGNLLNYAKTTLLFSGVDPNVITWNKVVLLHGP-PGTGKTSLCKALAQKLSIQLGDRYGQLLEINSHSLFSKWFSESGKLVQKMFDKIQ------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -----------------------------------------PSVRFRDLWESLVYDGA--IQQTLLRYALSILHFSGVNPSLVAWNKTILLHGP-PGTGKTSLCKALAQKLSILLSPRHARLVEINSHSLFSKWFSESGKLVTRLFAQVRELAANEQTLVIILVDEVESLAAARSASV-NGSEPSDAVRVVNALLTQIDQLSYFPNVMLLTTSNLAGAVDAFVDRADLKIHVGPPSLAARYRILHLALSELVRKGI--------------------------------------- Morel2 LHVEARLAMRDRVRAFLVRTFVEHIRIGELSIHVESVMMAHPCEELEGVWDSLIFEDR--LEVKLLEYVYTTILFSNVNPHLVAWNRVVLLHGP-PGTGKTSLCRGLAQTLGIRLSRRFTKLLEINCHSLFSKWFSESGKLVHRMFDQIWRMVDDDDTFVCVLIDEVESLAAARKAAL-SGNEPSDSIRVVNALLTQIDRLKRRKNVLVLTTSNITEAIDAFIDRADIKMYIGLPPPKAIYTILCSSLNELGRAGIIISELAQG--MSGRAIRKLPFLAHALTALFLMVQQEQEC Mucci2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma VHIEVCQNIKKHVFEFLLAANVEFISIFDAAIHVDELSAASPA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 VHIEVRVSIRHLVHSYLLASSVERIVASEFKIHVEEVMAATPNRGWDGLWDSLIYSDD--IKLKLLEYIHATLILSNVDFNLVSWNRVILLHGP-PGTGKTSLCRALAQKLSIRLSHRHSRLLEINSHSLFSRWFSESGKLVQRLFASINELIDEEDTFVVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLKHRKNVLVMSTSNLVKAIDAFVDRADIIQYVDLPPSEAIYEILRGSLSEIIGKGLILSARCRKQRMSGRALRRLPVLALALEAMEKVVEDQATE Polpo IDVEIELLIRDDVRSFILKNDIKLLKIYDFDIHPEESSPYQPNYQYSTLWENLIYDGN--IKPKLLQYLSTILKFSNIDQNIISHNKIILLNGP-PGTGKTSLCKALAQKISIGRQHNNVTLIEINSHSLFSKWFSESGKLVMKVFEKIKELAEDTDSLVVVLIDEVESLTAARKAAI-SGGEPSDSIRVVNAFLTQLDRLKYLPNVLILTTSNLVGAVDAFIDRVDIKQFIGPPTIQARWDIIKSCLVELERKNLIIAHLSDG--FSGRSLRKIPFIAFSFRVMNLDCQQQK-- Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 VHVEVRVAIRRLVEELLLASCVEHLATSELDIHVSNVSAASPNKSWEGLWDNLIYSDD--IKMSLLDYIYATVVLSRVDFNIVTWNRVVLLHGP-PGTGKTSLCRALSQKLAIRLSDRNCRLLEINSHSLFSRWFSESGKLVQRLFASVNDMIDDEGSFVVVLIDEVESLTAARAGVA-AGTEPSDALRVVNALLTQLDKLRYRPNVLVLSTSNLAKAIDAFVDRADVVRYIDLPPAKAVYEILRSCLLEFVAKGVVIAERCRAQKMSGRALRRLPVLAFALAALERVVEEQGTE Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 LHVEVRLKIRRLMCQHLLAQNVDRVWIGELSLHISDVPAASPSLSLEGVWDSLIYEGD--VKNKLLNYIYSTLLFSMVDFNIVSWNRVVLLHGP-PGTGKTSLCRALAQKLAIRLSDRHGKLIEINSHSLFSKWFSESGKLVQRLFSQVTEMVDDERSFVVVLIDEVESLTAARAGAM-SGKEPSDALRVVNALLTQLDKLKHRKNCLVMTTSNLSEAIDAFIDRADIKQYIGLPPAAAVYWILQTCLQEIMRAGLILAHRCKG--LSGRTLRRLPVLAHALEAMCKCVEEEGKE Rozal11 --VECRLKLQILIQKWLLTDIVDMMRIVAFKVYLDECPSSSPCLNFEDMWENLIFEID--VKDQLMNYAATAILFGHVDLMKICCNRIILFHGE-PGTGKTTLCKALAQKLAIRFVPKEARFIEINAHSLFSKWFSESGKLVVALFKSLEHIINDETTLTFLLIDEVESLTAARTAAL-KGNEPSDSIRVVNALLTEIDKLKYKSNVMIFATSNLPDSIVSLKDDND------------------------------LSGQLSG--LSGRVLRKLPLLAYSLSALEKQSRIEIEA Sacce1 YIVDLQVRLKAVVKRKLLSLFVKKISIEQFIIYPQTLNLVNPGTTFEGQWESLYFGNN--IKERLYSYATISLKIADITTLI-TNNKLLLVHGP-PGTGKTTLCKALCQKLSVRREFSGII-IELSCARIFSKWFGESSKNISIVFKDIEELLKVNGIFICLLIDEVEAIASSRTNLS-SRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIIIAIKCSTVDISGRTIRKLPLMCLSVLALAMSARKLSAA Salro LTIEVCLAIEGAVGEVLLTHNATSIRC--PSVCVEEVTSALPAAEFDNLWDTLIYDTD--VKQNLLSFATTTLLFSNVNPDIISWNRVVLLHGP-PGTGKTTLCKALAQKLTIRFCKRHGQLIEINSHSLFSKWFSESGKLVGKMFQSIRELIENEDSFVCVLIDEVESLAAARRAAT-SGTEPSDAIRVVNALLTQIDQLKTYKNVLILTTSNITEAIDAFVDRADLKFFIGLPGINARYQILSSCVRELMRTGLVLARLCEG--LSGRMLRKLPFLAFALEALRVAIEREHQS Schco3 VHVEVRLKVRDIVDSYLLASTVEKISASEFEIHVDDTNAATPNRNWEGLWDSLIYADD--TKLRLLDYIHATLDLSDIDLNLISWNRVVLLHGP-PGTGKTSLCRALAQKLSIRLSHRQARLLEINSHSLFSKWFSESGKLVQRLFNNITELIDEDDAFLVVLIDEVESLTAARAGAM-AGTEPSDGLRVVNALLTQLDKLKQRKNVLIMSTSNLVKAIDAFVDRADIVQYIDLPPQEAIYDIMRSSLCELIGKGIILAAICRQQNLSGRALRRLPVLALALEGMEKVVREQEKE Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar -----------------------MIALTEVEIVL-------PEM----------------VKSHALVYIH--------ELGVVYESSLATFCDPYLKTGKTSLAKSLAQKISIRMNDRYGQLITVNSHSVLSKFFSESGKLVQKLFQQIHEVLHP-DTFVCVLVDEIESLATSR--AT-SSSDPSDSVRAVNAMLTQLDKLAMYANILIIATTNLTGALDAFVDRADLCVQIALPNTSIRYEILRRSLQDLIRCRIIIAKDCEN--LSGRALKRLAFVTHLLEQLAETSKTRPSG Spipu1 LHIEVCLATRRHVQDFLLRINVEWIRVCELSIHVENVVTSNPAKGLHGLWESLIYDNN--IQLNLLDYVYTSMLFGGVDPHIISVNRVALLHGP-PGTGKTSLCRALAQKLAIRLADRHGKLIEINSHSLFSKFFSESGKLVMKMFQQIHEMLEDDDAFVCVLIDEVESLSAARKAAL-SGMEPSDAIRVVNALLTQLDQLRKRKNVLILTTSNITEAIDAFIDRVDIKQFIPPPSHRARYAILSSCLTELIQKRIIVAGDCEG--FSGRTLRKLPFLAHATQALSMAVQAEKSN Sporo1 --VEVRLKLRKMLDHHLLEQNIERVWIGELQLHLSDVPAASPSLSLEGVWDTLIYEGQ--VKEKLLGYIYSTMLFSSVDFNIVTWNRVVLLHGP-PGTGKTSLCRSLAQKLAIRLSDRHGKLIEINSHSLFSKWFSESGKLVQRLFAQVTEMVDDPNCFVVVLIDEVESLTAARAGAM-SGKEPSDALRVVNALLTQLDKLKHRKNCLVMTTSNLSSAIDAFIDRADIKQYIGLPPTAAVYWILQSCLNEIMRAGLILAEKCQG--MSGRTLRRLPVLAHALKAMEKCVEEEGRE Stehi1 LHIEVRLKIRNAANTYILSSSVDRIIACELQIHVEEVMAATPSKMWDGLWDSLIFSDD--TKSRLLDYIYATVLFSDVDFNIVTWNRVVLLHGP-PGTGKTSLCRALAQKLSIRLSHKHSRLLEINSHSLFSRWFSESGKLVQGLFSSVMDLVEDEETFVTVLIDEVESLTAARAGAM-AGTEPSDALRVVNALLTQLDKLRYKKNVLVVSTSNLAKAIDAFVDRADIVQYIDLPPREAVYEILRSCLLELINKGVVLAQKCRDQGMSGRSLRRLPVLAHALGAMEKVVENREAE Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr GVVEALLFIKAAVAAFLMRANVKRLDI--PEVMVGEFASASPAVEFDGVWESLVYDSA--IKANLVRYVQVAMQLSGVDTNLVAFNRVVLLHGP-PGTGKTSLCKALAHKLAIRLSSRHGQLIEINAHSLFSKWFSESGKLVTRLFSMIRELVADSDTFVVVLIDEVESLTAARTSAL-AGTEPSDSIRVVNALLTQIDLIKAYPNVAILTTSNITGAIDAFVDRADIKQFIGLPSRSARYGILASSVTDLMRAGVVVADAAQG--LSGRSLRKLP---VALAGLLAAAEAEMAS Treme1 --VEVRLLIPTAVRALILQRNVEQIIVAEVNIHLESVSAATPAQSLEGLWENLIYPPP--LKSTLLNMVRTSMVLGGVNPNIVALNRLVLLHGP-PGTGKTSLCRALAQKLSIRLSDTHGKLVEINSHSLFSKWFSESGKLVQKLFSSVMEMVEREDCFVVVLIDEVESLTIARDSFS-GASEPGDALRVVNALLTQLDKLRSKTNVLVLTTSNLSHTIVAFIDRADIKEYVPPPIPEAIYWILRTTLVELMNRGLVVAQECHSHGLSGRFLRRIPALALAVEAFFKVIENEVSD Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 VHVEVRLRVRLEVISLLLATNVDRIRIAEIQVHVDDTTAASPNRTLDGVWDTLIYPDN--IKAKLLNYIYTTLLFSAVDFNLVSWNRVVLLHGP-PGTGKTSLCKALAQKLAIRLSHRHGKLVEINSHSLFSKWFSESGKLVQRLFSMITEMVEDDDAFVVVLIDEVESLTAARSAAA-QGSEPTDSIRVVNALLTQLDKLKHRKNVLIMTTSNMTESIDAFIDRADIKQYVGLPPAEAIYWILESCLTELMRVGLVLAQSC--QGLSGRSLRRLPVLAHALEAMAKAVQETSRE Walse1 ------MR-------FLVALDIRTIKLAAFVVHSNKEKSASPNGQLEGLWDTLHFDYN--IKDKLLNYINTTIKFSNIDQKLISWNQIILLHGP-PGTGKTSLAKALAHNLSIRLNETQGRLVEINAHSLFSKWFSESGKLVQAMFDSINKLAEDDSVFVTLLIDEVESLTAARQASL-SGNEPSDALRVVNALLTQIDKLKQRKNVLIIATSNLTNAIDAFMDRADIKQYIGNPSTKAIEKVLNGCLNELVIKGLIIAAVAKTHEASGRFLRKLPLLAYTIDSMKVCIEENK-- Zygro1 YIVDAHIRLKKVIGKRLLSLFISKIYCDKFNINLQTLSQTRPSRELEGLWESLYFDDR--IKQRMYSYATIALKIA--SSAF-ANNKLLLVQGP-PGTGKTTICKALCQKLSIRKDFSGVV-IEISCSRIFSRWFGESSKNLATIFADVENLLKFHCSFVCLLIDEVEAIAFSRNSLM-NKNESTDGVRVVSTLLTQLDLLKKYNNFLVLATSNLVESLDAFIDRADGVFYIGNPSKGGIAKILTSSLDDLISKKVLIAEKCS--------------VC---------------- [Cluster3365.fasta_al_trimmed; alignment length = 48] Allma1 --LTPAGTEYQPSIIRRKRKWGFLARAN-SKAGRKILHRRMLKGRKYL Ashgo11 GAFTPAGNTYQPSTLKRKRRVGFLARAR-SRTGRNILKRRREKGRWYL Aspfu1 TPLTQSRATYNPSRRVQKRRHGFLARLR-SRGGRKVLQHRRAKGRKSL Aurde31 ------GNEYQPSQRKRKRRHGFLARMK-TKGGRAVLARRRRKGRKFL Batde5 ------GQEYNPSTLVRKRRFGFLKRLK-TLGGRKILFRRMLKGRRRL Botbo1 SSLASSGAEYQPSVRKRKRKHGFLARLK-TKNGRKMLARRRAKGRWSL Botci1 ------------------------------------------------ Caeel ------------------------------------------------ Canalb1 PLI---GNTYQPSTRKRKRKLGFLARLR-SIGGRKILERRRAKGRWFL Cangl SLIRNEGNTYQPSTLKRKRKFGFLARMT-NKRTAKIIKRRKEKGRWYL Capow SSLSPSGREYQPSNLKRKRKHGFLLRMS-TAAGRRVLLRRRLKGRRKL Catan2 PLLASAGSEYQPSIIRRKRKWGFLARNK-SRLGRKILARRVLKGRKWL Cioin ------------------------------------------------ CocheC53 ------------------------------------------------ Coere1 ------GNEYQPSNLKRKRRHGFLSRLR-TKNGRRIIQNRKLKGRKFL Conco1 ------GNEYQPSNIRRKRKHGFLARVR-SATGRKVLKRRLHKGRKRL Conpu1 ------GSEYQPSQRKRKRKHGFLARKR-TASGRRILMRRRAKGRSTL Copci SLTSSSGVEYQPSQRKRKRRHGFLARKK-TAAGRRVLANRLAKGRRYL Croqu1 TILRSSGNTYQPSQLKRKRRHGFLARLK-TKTGRKILFTRRAKGRKFL CryneH991 SIILSSGAFYQPSQRKRKNKHGFLSRLKGGKNGRKTLLRRLLKGRKFL Crypa2 ------------------------------------------------ Debha1 SLISDKGNSYQPSTLKRKRTFGFLARLR-SKNGRKILSRRKAKGRWYL Dekbr2 ------GNTYQPNTLRRKRRLGFLARMK-SISGRKIVKNRKQKGRWFL Dicdi ------------------------------------------------ Dmel ------------------------------------------------ Enthi ------------------------------------------------ Falba SLMQSAGNEYQPSTRRRKRKHGFLARKS-TPGGLRTLARRKNRGRKNM Fomme1 ------GTEYQPSQRKRKRKHGFLARRR-SPTGRKILVRRRAKGRKYL Fusgr1 ------------------------------------------------ Galma1 SILRTSGTEYQPSQRKRKRKHGFLARKR-SVGGRRVLSRRLAKGRKYL Ganpr1 SSPSPSGNTYQPNNLKRKRTFGFLRRKR-TVGGRKILLRRSMKGRKYL Gloin1 ------GREYQPSNIVRKRRHGFLARLR-SKSGRKILTRRRMKGRKYL Hisca1 STLLQ-RDTYNPSRRVQKRRHGFLARLK-SHSGRKILARRRAKGRKYL Klula1 EITLQSGNTFQPSTLKRKRRVGFLARAR-SRSGQQILKRRKNKGRWYL Lacbi2 NTSLQKGNEYQPSQRKRKRKHGFLARKR-SLGGQRILSRRLAKGRKYL Lenti61 STLPTSGQEYQPSQRKRKRKHGFLTRKR-SVNGRKMLARRKAKGRLYL Malgl1 SSLSARGSEYQPSQRKRKRKHGFLARLR-SRTGKKVLARRRAKGKTAV Mellp23 ------GHTYQPSQIKRKRRHGFLARLK-TKTGRKILWTRKAKGRKYL Mnele ------------------------------------------------ Monbr TPRAAQGREYQPSNLKRKRKHGFLRRLR-YKGGRKVLLRRLQKGRKVL Morel2 ------GREYQPSQRVRKRRHGFLARMK-SRGGRKIIHNRLLKGRKYL Mucci2 SILSASGNTYQPSQLVRKRRHGFLARLA-TKNGRRVIIRRRMKGRKFL Mydma ------------------------------------------------ Neucr2 ------------------------------------------------ Orpsp11 ------------------------------------------------ Pench1 SSLLSTRVTFRPSRRVQKRRHGYLARKR-DRNGRKTLIRRTLKGRKEL Phybl2 SFLSSSGNTYQPSNLVRKRRHGFLSRVA-TKNGRRVLARRRLKGRKFL Picst3 ------GNTYQPSTLKRKRTFGFLARLR-TKNGRKILSRRKAKGRWYL Plicr1 STFLSGGNEYQPSQRKRKRKHGFLARLK-STTGRKIMERRRAKGRKFL Polpo ------------------------------------------------ Pucgr2 HSLSSSGNTYQPSQLKRKRRHGFLARMK-TKTGRKIVFRRKAKGRKCL Punst1 AILGTSGHEYQPSQRKRKRKHGFLARNK-SVTGRKILVRRRAKGRKFL Rhior3 SILSSSGNTYQPSQLVRKRRHGFLARLA-TKNGRHTLNRRRMKGRKNL Rhoto1 SPLRPSGQEYQPSTLKRKRKHGFFKRLR-TKAGRNVLRRRFSKGRKYL Rozal11 ------FENYEPNYRKRKRKVGFLARLK-TKAGKKILFRRWMKGRKHL Sacce1 SVLRPQGNTYQPSTLKRKRTFGFLARAK-SKQGSKILKRRKLKGRWFL Salro ------GRTYQPSNLKRKRRHGFLKRLS-TVGGRRVLERRKAKGRKYL Schco3 AFLAPSGTEYQPSQRVRKRRHGFLSRLR-TKNGRRILQRRLKKGRRYL Schpo1 SILAGGGNEYQPSNRKRKRKHGFLSRIR-SVNGRRVLRDRRQKGRMYL Sorma ------------------------------------------------ Sphar ------------------------------------------------ Spipu1 ------------------------------------------------ Sporo1 ------------------------------------------------ Stehi1 ------GTEYQPSQRKRKNKHGFLTRKR-TVNGRKILARRKAKGRKIL Tapde11 ------------------------------------------------ Thetr ------------------------------------------------ Treme1 INLSTSGNSYQPSQRKRKRKHGFLSRSR-TKLGRKILSRRKTKGRKFL Trire2 ------------------------------------------------ Umbra1 PILS--GNTYQPSNLVRKRRHGFLARIT-KKNGRRVLQRRQLKGRKYL Ustma22 SITRISGSEYQPSQRIRKRRHGFLSRIK-TRNGRKTIMRRRFRGKAKL Walse1 ------------------------------------------------ Zygro1 ------GNTFQPSTLKRKRRVGFLARAR-SKQGSKILQRRKHKGRWFL [Cluster3368.fasta_al_trimmed; alignment length = 84] Allma1 ASSIRVRHILCEKHSKIMEALNALTVDKMSFDKVAERYSEDKAR-SGGSLGWMTRGS-MVGEFQDAAFKLTPSTVKTKFIIMVE Ashgo11 ------------------------------------------------------------------------------------ Aspfu1 ATSINVRHILCEKFSKKEEALEKLRN-GAKFDDVAREYSEDKAR-QGGSLGWKVRGS-LNADFEKAAYELEPSTVKTGFIIMVE Aurde31 ------------------------------------------------------------------------------------ Batde5 ANSIKVRHILCEKHSKIMEALELLKS-GQRFDKVAEQYSEDKAK-AGGSLGWMTRGS-MVGVFQDAAFLLVPSTVKSNFIIMVE Botbo1 ATHVNVRHILCEKQSKALEALEKIKG-GERFDKVAQEYSEDKAK-AGGSLGWKVRGS-MVGPFQEAAFALTPSSIKTAHIILVE Botci1 AQQINVRHILCSKHSKMTEALQKLEA-GASFDSVAREMSEDKAR-AGGALGWKGRGD-LDAEFEKVAFEMEASTVKTGFILMVE Caeel GTAVKVRHILCEKQGKALEAIEKLKS-GMKFNEVAAQYSEDKAR-SGGDLGWMTRGS-MVGPFQDAAFALSNSSVKTKFVIMVE Canalb1 ------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------ Catan2 ANAIKVRHILCEKHGKITEALEKLTVDKMSFDKVAEAYSEDKAR-QGGSLGWMSRGS-MVGEFQDAAFKLPISTVKTKFIIMVE Cioin ANSVKVRHILCEKHSKCMEAMEKIKA-GMKFNEVAQQYSEDKAR-SGGDLGWMIRGS-MVGPFQEAAFALPVSSVKTKFIIMVE CocheC53 ATSINVRHILCEKHSKKEEALEKIRN-GAKFDDVAREMSEDKAR-QGGSLGWKVRGS-LMQDFEKVAYELEPSTVKTSEIIMVE Coere1 ANAIFVRHILCEKHSKILEAEAMLKN-NIAFDAVAREYSEDKAK-VGGNLGKMVRGT-MVGPFQEAAFALQPSTVKTVHIIMVE Conco1 -----------------MEAMEKLKVDKLRFDKVAEQFSEDKAK-AGGSLGWMVRGS-MVGPFQDAAFALQPSTVKTVHIIMVE Conpu1 ATAINVRHILCEKHSRASEALQKIQE-GQRFDKVAQEYSEDKAK-AGGSLGWMTRGS-MVGPFQDAAFALTPSTVKTNFVIMVE Copci ATAVNVRHILCEKHSKASEALQKIQE-GQAFNKVAQEYSEDKAK-AGGSLGWMVRGS-MVGAFQDAAFALTPSTVKTNFIIMVE Croqu1 ANSLKVRHILCSKQSPALEAISRLKA-GAAFDRVAAELSEDKAR-NGGSLGWMTRGS-MVGPFQDAAFLLTPSTVKTNFVIMVE CryneH991 ------------------------------------------------------------------------------------ Crypa2 GLKIKIRHVLCEKKSRMDEALAKLEE-GVSFAEVARNYSEDKAK-QGGSLGEVTKDAPFDQKFKDCAWDLEPSTVKTDFIIMVE Debha1 ------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------ Dicdi ITQVKVRHILCEKEAKLMEAVNLIKS-GKTFNSVAQSHSEDKARVSSGLLGYIGRGD-MVQEFTDRAFNQPIGVFRTQFIILVE Dmel GNAVKVRHILCEKQGKITEAMEKLKA-GQKFPEVAAAYSEDKAR-QGGDLGWQIRGA-MVGPFQDAAFALPISTIKTKFIIMVE Enthi CTKIKVRHILCEKQSKILEALAKLEE-GKPFSQVATEYSEDKAN-QGGSLGWVIRGQ-MCGAFQDVAFNAPVGKFKTPFIVLVE Falba ------------------------------------------------------------------------------------ Fomme1 ATAVNVRHILCEKQSKALEALKLLEE-GQAFDKVAQTYSEDKAK-AGGSLGWMSRGS-MVGPFQEKAFELTPSSVKTTFVIMVE Fusgr1 ------------------------------------------------------------------------------------ Galma1 ATAVNVRHILCEKHSKAMEALQKIQE-GQSFNKVAQEYSEDKAK-AGGSLGWMIRGS-MVGPFQDAAFALTPSTVKTNFIIMVE Ganpr1 ANSVKVRHILCEKHSKVMEAMEQLKA-GVSFDKVAESFSEDKAK-AGGALGFMNRGS-MVGPFQDAAFQLKPSTVKTVHIIMVE Gloin1 ANSVKVRHILCEKHSKIMEALDKLTVENMRFDKVAELYSEDKAK-QGGSLGWMNRGS-MVGDFQDAAFALQPSTIKTKFIILVE Hisca1 ANSINVRHILCEKHSKKEEAAEKLRN-GAKFDDVAREFSEDKAR-QGGSLGWKVRGS-LNGEFEKVAYGLEPSTVKTGFIIMVE Klula1 ------------------------------------------------------------------------------------ Lacbi2 ATAVNVRHILCEKHSKATEALQKIQE-GQAFNKVAQEYSEDKAK-AGGSLGWMVRGS-MVGAFQDVAFALTPSTVKTNFIIMVE Lenti61 ATSVNVRHILCEKQSKALEALQKIQE-GQRFDKVAQEYSEDKAK-AGGSLGWQVRGS-MVGAFQDAAFALQPSTVKTQFIIMVE Malgl1 ------------------------------------------------------------------------------------ Mellp23 ANSLKVRHILCSKQSTALEAIARLKA-GVGFDKVAAELSEDKAR-NGGSLGWMTRGS-MVGPFQEAAFLLTPSTVKTNF----- Mnele GTAVKVRHILCEKQSKSMEALAELQN-GVKFNEVATKYSEDKAR-SGGDLGWMTRGS-MVGPFQDAAFALPKSTVKTKFIIMVE Monbr GTAVEVRHILCEKHGKCMQALEKLRAAYKPEDQVAMEFSEDKAR-SGGNLGWMTRGG-MVGPFQDTAFSMPITKVKTKFIIMVT Morel2 ANSVKVRHILCDKQSKALEAIEKLKA-GIAFNKVAEAYSDDKAK-EGGSLGWMVRGS-MVGAFQDAAFLLQPSSIKTQHVIMVE Mucci2 AQSVKVRHILCEKHSKAMEALAKIKEENMRFDKVAEQYSEDKAK-AGGALGWMNRGG-MVGAFQDAAFALQPSSVKTKFIIMVE Mydma GTSVKVRHILCEKQGKCLEAMALLKA-GKRFSDVATQYSEDKAR-SGGDLGWMVRGS-MVGPFQDAAFALQPSTVKTNFIIMIE Neucr2 AQSINVRHILCEKHGKKEEALAKIRD-GADFGAVAREYSEDKAR-TGGSLGWKQKGT-LDPEFEKVAFALETSSVKTQFIIMVE Orpsp11 ANAIRVRHILCEKYSKVMEAMAKLQA-GERFDKVAEQYSEDKAK-HGGSLGWQSRGQ-MVGPFQDAAFKLQTSTVKTTFIIMVE Pench1 AQSINVRHILCEKHAKKEEALEKLRN-GTKFDEVAREFSEDKAR-QGGSLGWKTKGG-LDPAFENVAFELETSTVKTAFIIMVE Phybl2 ATAVKVRHILCEKHGRVMEAMAKIKEENMRFDKVAELYSEDKAK-AGGALGWLIRGA-MVGDFQDAAFALQPSTVKTKFLIMVP Picst3 ------------------------------------------------------------------------------------ Plicr1 ATAVNVRHILCEKHSKATEALQKITE-GQRFDKVAQEYSEDKAK-AGGSLGWMVRGS-MVGPFQDAAFLLEPSTVKTTHIIMVE Polpo ------------------------------------------------------------------------------------ Pucgr2 ANSLKVRHILCSKQSNALEAIARLKS-GVSFDKVASELSEDKAR-NGGSLGWMTRGS-MVGPFQEAAFQLQTSSIKTNFVIMVE Punst1 ATAVNVRHILCEKHSKATEALEKIQN-GERFDKVAQEYSEDKAK-AGGSLGWMTRGS-MVGPFQDAAFALQPSTTKTSFIIMVE Rhior3 AQSV-----------KAMEALAKIKEENMRFDKVAELYSEDKAK-AG-------------------AFALQPSTVKTKFIIMVE Rhoto1 AQSLKLRHILCEKASKAQQALERLKA-GEAFDKVASDMSEDKAR-QGGSLGWMNRTG-MVGPFQDAAFDIPVSTIKTKFIVMVE Rozal11 ANSLKLRHILCEKHSKAMEALDKIKVAKMNFAKVAEIYSEDKAR-SGGSLGWMSRGS-MVGPFQDAAFLLPSSTVKTKFCIIIS Sacce1 ------------------------------------------------------------------------------------ Salro GTNVEVRHILCEKHSKAMQALEQLRQAYKPADKVASEFSEDKAK-SGGNLGWMARGS-MVGPFQDAAFALEVSKVKTKFIIMVT Schco3 TTAVNVRHILCEKHSKATEALQKIQE-GVAFNKVAQEYSEDKAK-AGGSLGWMVRGS-MVGPFQEAAFALTPSTVKTNFIIMVE Schpo1 ------------------------------------------------------------------------------------ Sorma AQSINVRHILCEKHGKKEEALAKIRD-GADFGAVAREYSEDKAR-TGGSLGWKQKGT-LDPEFERVAFALETSTAKTPFIIMVE Sphar ------------------------------------------------------------------------------------ Spipu1 ------------------------------------------------------------------------------------ Sporo1 ----QLRHILCEKQSKSLEALEKLQS-GVSFDKVATEYSEDKAR-SGGSLGWVIRTG-MIGAFQEVCFDIPVSTVKSKF----- Stehi1 ATAINVRHILCEKHSRATEALEKIQG-GERFDKVAQEYSEDKAK-AGGSLGWMTRGS-MVGPFQEAAFALQPSTVKTTHIIMVE Tapde11 ANSVNVRHIMCEKQSKALQAIEKLRA-GEKFNVVASELSEDKAK-AGGSLGWQTRQQ-MIGPFAEVAFQLQPSTLKTKFIDHNG Thetr ------------------------------------------------------------------------------------ Treme1 ------------------------------------------------------------------------------------ Trire2 AMSINVRHILCEKHSKKEEALAKLSE-GVKFDEVARTYSEDKAR-QGGSLGWKTKGS-LDPTFEEVAFSLEPSTAKTSFIIMVS Umbra1 ATSVKVRHILCEKHGRAMEALAKIKEDNMRFDKVAELYSEDKAK-AGGSLGWMVRGS-MVGPFQDAAFALQPSTVKTVHIIMVE Ustma22 ------------------------------------------------------------------------------------ Walse1 AQHIQLRHILTEKHSKAAEALEKINN-GEKFDKVAMEYSQDKAR-AGGLLGLKKKTD-LVEPISSIAFDLPINQVKSEFILLVE Zygro1 ------------------------------------------------------------------------------------ [Cluster3369.fasta_al_trimmed; alignment length = 180] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 EEGIILR-VLPEFVKNSIESGISIKWKGERHAVVYGAVLVNLPTVIEVNK-SVDRKNMLKAFDVSQGYDYKHGI-TAPLYNVRNRRFRRR-MTGSEIDVDRTVEFLLKQDAEEFTYELVDELELEQDNGDDEDDELGELESILQQNRDKLAKAT-NPLLKSRFVDSIAKLEKEVDIKRKQ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 EEQFILR--VPDRIRSIAQDRVSFKFRDSRRGAFFEAKLVDLPCIIEAQK-TLDRKNMFKVADISQEFIWPHGI-TPPLHHVRKRRFRKR-INRRTIEVEQEVERLLEADADSVQYTVLEDAELAASEASEEEEEIRDLEAAVAKKHSEIASSV-NPLLKKRFEDALRKLQADVEMKYAQ Batde5 EEHLILR--VPPQLRLHVQKRFTLKFTDARKGEALPVQLVDLPCILESLK-TIDNKQFYKIADVAQDGSWPDGI-SPPFKNVRKRRFRKR-ISKKAIEVEQEIERLLLADAVDVKYDVHDDSDLAASEDDEEEHEIQDLERKLFEKNAQAASQV-NPIMRKRFEEIVGKLTSELDIKHQQ Botbo1 EEQFILR--LPDRLRKMVQARVWFKFKDSRRAVFYTSKLVDLPCIIEAQK-TLDNRQMYKVADICQDFIWPHGL-TPPLKHVRKRRFRKR-VNRTTIEVEQEVERLIEEDAAEVKYEVLEDDDLAADED-ESAEEIRDLEAAVEKKSAEIAGAF-NPLIKKRFEDALKKLKADLEGRLAQ Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ESHIVLR--VPGRIEKIIQSDFSLNLNDARNSTVLNGKILDLPTITEIHK-TLDNKSLYKVADVSQQWQYPHGL-TPPMKSARKKRFRKT-KKKKFMDVEKELKRLLRADADSVKWEIVEQRHVTYDESDVGD----------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ESGIILR-VLPDFIKNSIESGISIKWKGERHAILYGAILVDLPTIIEVNK-SVDRKNLFKTFDVTQKYHYKHGL-TPPLYNVRNRRFRRQ-MHADEFEAEKIVDMLLKADAEDVKFDLIADLDLEEDNGEDEDDELNELVSTLEHTKDKLEKAT-NPLLKSRFVDSIKKLEKEVELKKKQ Capow EQQFILR--VPSRLAEYLDKNLSITYADTRQFKVMDATLVDLPTIIESQK-SVDKRNFYKTADICQ--IYPHGL-SAPLKNVRKKRFRKS-AASKLTNVQTAVARLLRDNASSDTYELVDKDNTASDSDSDSSAEVTRLETRVAEVRKQLAATN-NPLLSARVRASLRQAEEELNSKTQA Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ENQFLLR--LPEKLKEILLAGLAIQVQDNRHGTVLTSKIFDLPCVIESLK-TLDMKTFYKTADLSQKFLWAHGI-TPPLKNVRKRRFRKT-ARKKYIDIEKEVKRLLKADAVSVR----------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 EEQFILR--VLAHFSKLVAERLEIKFRDERNAVVFVAKLVDMPTITESYR-TVDKKQLLKTADVCQDIIYPDGL-APPLANVRKNRFRPR-ISKGKIDIEQEVLRLLEDDAMAVKFDIY-------DEQGE------------------------------------------------- Conco1 EEHTILR--VPPKLKELVDKRVKLEFQEDRKGTFYSTRLVDLPCIIESHK-TIDSKNLYKIADISQPYLWPDGI-TPPLKNTRKRRFRKR-TTKQIGEVEAELEKLLEEDAIDVVYDLHEDTNAPSEDDDDDDDTISNMEKDIEKKVQELTRIT-NPIIRKRFEDTIGKQRALMAEYQEQ Conpu1 EEQFIIR--MPEKLRKMVASRVWFKFKDSRRGIFYSFKLVDLPCIIEAQK-TLDSKQMFKVADICQEFIWPHGI-TPPLHHARKRRFRKR-VNKRTIEVEEEVERLLAEDAAEVQYDVLEDEDLAAEED-DEDEEIRDLQAAVAKKGSEIASSA-NPLIKKRFEDALKKLQADLDMKLLQ Copci EEQFILR--FPEKLRKMVANRVWFKFKDSRRAVFYSAKLVDLPCIIESQK-TLDNKQMFKVADICQDFVWPHGI-TPPLHHVRKRRFRKR-VNRRTIEVEQEVERLLEEDATEVKY----DEELAAEEE-SSEEEIRDLQAAVAKKENEITSSA-NPLLKKRFQDALKKLTADLELKISQ Croqu1 EEQFILK--MPEKLRGLVDGRLFFKFKDSRRGVFYGMKLVDLPCIIESQK-TFDNKHVFKVADICQDFICPHGI-TPPLHHVRKRRFRKR-LNKRTIEVERAVERLLEEDADQVIIDIVDDSDLAAEDDDEDDGELKDLEAAINRKKSEIAKAA-NVILRKRFEEALKKLTIELESKKTQ CryneH991 EEQFILR--VPTGLRDMVKGKVEFKFLDPRRAAFYAAKLVDLPNIIEAQK-TFDNRHLFKIADISQEYIWPHGI-TPPMKHVRKRRFRKR-MSRLAIEVEESVEDLLKKDAEDTAFDLIDDQELAASEDDGATSEIKALETVIDKKRAGFTGG--NPIMVKRFEETIAGLQADVTAKIGA Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 EQGIIIR-FVNDFVHNAVDSGLNVKWVTKVKAVVYSAKLLDLPTITELYK-TIDKKNIFKTFDICQ----KNGL-IYPFEEVY-RRFKPRKVNHRVVEIEQRIDELIRLDAEESHFEIVDEEELAKDEDEDDEEEIADLENAVEVHRKGLASAT-HKMMKMKFQTSYNTLKASLDTKKRE Dekbr2 EDGIILR-MLPDTLRACVESGIAVKWKDRKRAVLYGGKLVNLPTIIEVHK-SINKKSIYKTMDVCQ-----DGI-TEPMIQCK-SRFEKR-YEEQVIQVEDEVDRLLKLDADTSTYEFIDDSELDKDEDEDEDEEISELESTIEQKHKDLEKAN-NPIMRNRINDVINRLRQELDIKKSQ Dicdi EDQILFR--LPDQVRNMIKQKVDFHFKNDRQIQIYNANLVDLPCIVESHK-TFDRVNFYKTADIGQNNILQTGL-TAATKDIVKRKFKT--YNRDKITIEEELVRLIKPGSEEIEFVSLAPDDLSKDRGDREG-------------------------------------------KFKC Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ESHFLLR--LPGPLRESLSRHYGIQFQGRRFATIVSARLVDLPCIIESHR-SLDQRQFYKVGDISQSFLWPHGL-APPLRYIRERRLSD--FPPREITVDAEVQRLLALDSVYRTVSFAQPADLAADGHSPSPEMLANLNTEYNAKYQLASRQR-NPVMRQRFLEDLAAL----DARRHE Fomme1 EEQFILR--FPEKLRKMVSARVWIKFKDSRRAVFYTAKLVDLPCIIESQK-TLDNKQMFKVSDICQDFIWPHGI-TPPLHHVRKRRFRKR-INRRTIEVEQEVERLLEEDANQIEYVVLEDEELAADED-EEDEEIRDLEAAVAKKNAEIASSA-NPIIKRRFEDALRKLQADLDSKLLQ Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 EEQFILR--MPDKLRKAISSRIWFKFKDSRRAIFYSAKLVDLPCVVESQK-TLDGKQMFKVADICQEFIWPHGL-TPPLHHVRKRRFRKR-VNRRTIEVEQEVERLLDEDASEVKYDVLEDEELAADED-ESEEEIRDLEAAVAKKRHEIASSA-NPLIRKRFEDALKKLTADLEMKTVQ Ganpr1 EDHFMLR--LPDSAKKIVRDRIKIRFHNSRQATFHRATLHDLPTVTESHV-THDKKSIYKVADISQKYKSNDGI-TPPMRGVRKRRFRKRAVKKMTYDVELETIKLLEEDAVRSVWEWTDEDDLALNEVEEDVADLADLEKKLRDKQKEMRETR-NDIRRTALARVYRDVLDMRDSTKKK Gloin1 EEQFILRLMVPQKFREKVKTGIGIIFKDPRRAIFYRAKLVDLPCIIEAQK-TFNKIQYYKVADICQEFEWPDGLTTPPLKNVRKRRFRKR-ISAKL--VKQE---------------------------------------------------------KK------------------- Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 EEGIILR-VLPEFVKNSIESGVSIKWKGERHAVVYGAVLVNLPSIIEVNK-SVDRKNLLKTFDVSQRYDYKHGI-TPPLYNARNRRFRHR-MGPTAFDVERTVEKLLKLDAEEFGYELVNELELEQDNGDDEDDELRELESTLELNRNKASRTT-NPLLKTRFLESIKKLEKEVELKRKQ Lacbi2 EEQFILR--MPDRLRKTVAARVWFKFKDSRRAVFYSSKLVDLPCIIESQK-TLDSKQMFKVADICQEFIWPHGI-TPPLHHVRKRRFRKR-VNRRTIEVEQEVERLLDEDATEVKYDILEDEELAAEEE-ESEEEIRDLEAAVFKKGKEIASSA-NPLIRKRFEDALKKLTSDLEMKLAQ Lenti61 EEQFILR--MPERLRKMVQARVWFKFKDSRRAVFYSSKLVDLPCIIESQK-TLDNKQMFKVADICQEFIYPHGI-TPPLKHVRKRRFRKR-VNRRTIEVEQEVERLLEADAADVKYDVLEDEELAADEDEEEDEEIRDLEAAVNKKQTEIASSA-NPLIKRRFEDALKKLQADLDTKMAQ Malgl1 EEQLILR--VPDALRQAIRRRVWFKFKDSRRAVFYAAKLVDLPCIIESHK-TLDNKQIFKIADISQEYIYPHGI-TPPMQWARKRRFRKR-VHNRSIDVEKEVEGLLNDDAERVTYEFIDDQDLAADDDDDDDAECREIESLIKRKQHDIESTM-NALIKSRHQQALRKLQVEHDAKKRH Mellp23 EEQFILK--MPEKLRELVEKRVFMKFKDSRRGIFFGMKLVDLPCIIESQK-TFDNKHVFKVADICQDFIYPHGI-TPPLHHVRKRRFRKR-LNKRTIEVERAVERLLEEDADQVIIDIVDDSDLAADDDDDDDGELKDLEAAINRKRGEIAKAA-NVILRKRFEEALKKLTIELESKKTQ Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 EEQFILR--LPDRFREKVIARVKLNFTDARRGTFFPTKLVDLPTIIEAQK-TLNGKQMYKIADISQEYIWPDGL-TNPLKNVRKRRFRKR-VSKVAVEVEAEIERLLQEDAEEVVYEIREEKDLLAEEEEEDDDEIKELASKVQENEEKFQSAP-NEILKKRFNLIVEQLRKELELKKSQ Mucci2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mydma ENEIVLR--MPSSLRDALQSGLQIDFEDARHATVFAAKLYDLPCIVETWK-TFDKKSLWKTGDMCQKYQYAHGL-TPPLKNVRKRRFRKT-AKQKYIDIEKEVKRLLRADAVDVKFEIINEIDIGGDEGDILPKKLMEIREKKLEQEMRVRKAA-NPFLKQRFQTELDNLKQQEEKFIAE Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 EEHFLLR--MPDRLRQAVQNRFKITFSDSRHATVYTAKLVDLPCIIESQK-TLDRKQFYKIADISQDYSYPHGI-SAPLKYVRKRRFRKR-MSKRVIEVEREVERLLQDDAEDVTYDFGI-ESLAADEGDEGDEEIDELEAKIEEKNEQIKSVVGNQIMKKRFVDQLHALEKELEEKQ-- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 EEQFILR--MPERLRKMVASRVWFKFKDSRRAVFYSSKLVDLPCIVESQK-TLDNKQMFKTADICQEFIWPHGI-TPPLHHVRKRRFRKR-VNRRTIEVEQEVDRLLEEDATEVKYDILDDEDLAAEEE-EEEEEIRDLEAAVAKKGNEIASSA-NPLIRKRFEDALKKLSADLDMKMAQ Polpo EDQLILR--LPDRVRRMIKQKIDVQFKSDRAMVFFDASLFDLPCILESHK-TLDKTTYYKTADIGQ-----SGI-TPPTKEITKKRHRE--LSKDKVTIEEELVRIIKPGQEEVEFVTMEPEERKSDRENRGDQEADSLKKKVDDLQANFASLP-NKILKERQQKIIDKLQKEYTDKLKD Pucgr2 EEQFILK--LPNKLRELVESRIYFKFKDSRRGIFFGMKLVDLPCVIESQK-TFDNKHMFKIADICQDFIYPHGL-TPPLHHVRKRRFRKR-LNKRTIEVERAVERLLEEDADQVIIDIVDDSDLAADNDDEEEGELKDLEAAVNRKKIETAGAS-NLIVRKRFEEALKKLNLELESKKNQ Punst1 EEQFILR--MPERLRKMVQARVWFKFKDSRRAVFYSSKLVDLPCIIESQK-TLDNKQMFKVADICQEFIWPHGI-TPPLHHVRKRRFRKR-ANKRTIEVEQEVERLLEADANDVQYDVLEDEELAADED-DDDEEIRDLEAAVAKKNHEIAHSA-NPLIRKRFEDALKKLRTELDMKLGQ Rhior3 ----------------MAKKRVKLNFKDNRKGTLYDVLLVDLPTIIEAQK-TLDKKQFYKVADISQPYNYPHGL-TPPLKHVRKRRFRKK-LSKRAIEVEREVERLLEIDAEDVQYEVVDDEDLAADEEEDGDQEIAEIKQAIQRKTRDLLTAP-NAMLKNRFETDINNLKKSLTLKEAH Rhoto1 EEQFILR--VPPKLREQVDKRVWFKFKDSRRAVFYGAKLVDLPSIVESQRLTGVGGQTVKVADISQDFVYPHGI-TPPLKHVRKRRFRRR-ANRRTIEVETAVEKLLEADAEQVQFEMLDDSDLAKDEDGDGLEEMSDLDRAIAAKEVELSKAP-NPIFKKRFEEVIKKLATERDLKKNQ Rozal11 EEQLILR-ILDELLRNKIGNNLEIIFK------------VD-PSILDRME----------------NLLWPDGL-TNPLKDVRRRRFRKR-MAKKVIEIEKEVRRLLEEDAISEQSQDMDASDLAA-------NEIADIESKIAEKTQQLQKAN-NIVLKKRFQEALDKLQTSLQEKQAN Sacce1 ESGVILR-ILPEFVKNSLESGISIKWKNERHAVVYGAILVDLPTVIEVNK-SVDRKNLLKTFDVSQGYDYKHGI-SPPLYNVRNRRFRRK-MDPNEIDVEKVVDMLLKQDAEEVSYDLVDDLDLGADTGGEDDDELNELETTLAHTKHKLSKAT-NPLLKSRFIDSIKKLEKEAELKRKQ Salro EEVFVLR--LPVKLRTALDN-LGDRFVGGRPNVVFDAKLYNLPTVIEAHK-TADSNYVYKVGDVHQAVPFPHGL-TPPLRNVRRRRFRP--TAKPVVDIMEEVARLMNSDVDVHTFEVEKDFDTASDEDDEDDPAVVALEKKISKLEEDVRKAA-NPVVRRRHQLQLDAARAELAKMKGD Schco3 EEQFILR--MPERLRKMVQARVWFKFKDSRRGQFYSAKLVDLPCIIESQK-TIDNKQMFKVADICQEFIYPHGI-TPPLHHVRKRRFRHR-VNRRTIEVEQEVERLLEEDASETKYEVLEDEELAADEDDESEEEIRDLEAAVAKKTSEVASSV-NPLIRRRFEETLKKLSSDLEMKMAQ Schpo1 EEQIILR--LPEYVRKAIENRIWVKFKDQRRAVVYAAKLVDLPCIIESNK-SFDKKVIFKAADICQDYIYPHGL-TTPMHWVRQKRFRKR-VSNRTIEVENEVDRLLAMDAESTSNELIDEDDLAGSEEEEEEEFISELESSIQKRRKDADEAT-NPILRNRFLADVNRMVTELELKRTQ Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ----------------------------TRHLKVLKGTLMDLPCIVECQK-TLDGINFYKSADICQQYVWPHGI-TPPLKNVRKRRWRKTAPNKFNQEVVNEVRNLRMADAVSYSYEVID-----------------------------------TKVCG-------------------- Spipu1 EEHFILR--MPEKLREAVKARFNVTFYDPRRATFYRAKLVDLPCIIESHK-TLDNKQFYKVADISQEYTWPHGL-TPPLWNVRKRRFRKR-ISKRTIEVEREVVRLLEADAENVLFEV--DDALTADEESEDEAEIRDLESKIEDNRAKLAVQI-NPIMRKRFEDIVKRFTTQLHSKRAE Sporo1 ----------------------------------YGAKLVDLPALLESQRLTGVGGQTVKVADVSQDFVYPHGV-TPPLKHVRKRRFRRR-INRRTIEVETAVEKLLEADAEKVQFEMLDDSDLANDEDGDGLEEMGDLDKAIASKETELAKAA-NPIFKKRFEEMIKKLTVDRDSKRAQ Stehi1 EEQFILR--MPERLKKAVASRVWFKFKDSRRAVFYSSKLVDLPCIIESQK-TLDNKQMFKVADICQDFIWPHGI-SPPLHHVRKRRFRKR-INKRTIEVEQEVERLLEEDADEVKFDVLDDEELAAEEDEESEEEIGDLEKAVQKKEHEVASAG-NPLIRRRFEDMLKKLSADLEMKRAQ Tapde11 ENHIILR--FKEFVRGLIDAKLSIKFKDARNAVVYAAKLVDLPTITEVHK-SFDKKNVYKVADVCQDFVFPHGL-TPPLRNVRTRRFRKR-ASAKTIEVEKEVDRLFSLDSEQTTYTIMDYEDLAADTQTPSAESITNLQHVIANKKSDIDRAI-NPIMKQRLITTLRKFESELEMKMAE Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 EEQWILR--VP-GLREIVKGKVEFKFLDSRRATFYASKLVDLPSIIESQK-THDNRHLFKVADISQDFIWPHGI-TPPLRHVRKRRFRKR-ISRRTIEVEEQVEELLKRDADESTFDLIEDRELANDEDEEAASEIKNIEATIERKRAGFTGG--NPIMQKRFEETLAGLLIDVVRKAEA Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 EEQFILR--MPNKLRDMVRKRVKFVFKDPRHGHFFDTKLVDLPTIIESQK-TIDQKQLYKVADISQ-YLYPDGV-TPPLKHVRKRRFRKR-LSKRTIEVEKEVERLLEVDAEDVRYEMSDDEDLAADDDDDDDQEILEIKAAIQRKNVDLNSAT-NAILKQRFETVVENLKKQLALKEAH Ustma22 EEQLIFR--MPDKLRDSIQKRVWFKFKDSRRAVVFSAKLVDLPTITESHK-TLDNRQFFKVADIAQDFIYPHGI-TPPMQWARKRRFRKR-AARRAIETEKEVERLLKADAEQVEYEMIDDEDLAADDDDDDDAECRELETLVRRKQADVDGTM-NLIIKNRHQQALRKLATERDMKRNQ Walse1 EEQFILR--MPDRLREMVQKRVWFKFKDSRRAQFRSAKLVDLPTIIESQK-TLDNKQMFKIADICQEYVWPHGM-TPPMKHARKRRFRKR-VNRQTIEVEEEVERLLTQDSEKVEYEVMDDMDLAADEDDEDDEEIRDVETALTKKRAETATTA-NPIIKRRFEDALRKLQADLDAKKQQ Zygro1 EEGIILR-ILPEFVKNSIESGISIKWKGQRHAVVYGAVLVNLPTVIEVNK-SVDRKNLLKTLDVCQPYDYKHGI-TPALYNVRNRRFRRR-MGQGEFDVEQVVERLLKFDAEDVQYELIDDLDLDADNGEEDEDELHELETTLIHTKTKLQKAT-NPLLKSRFIDSIVKLEKEVELKRKQ [Cluster3372.fasta_al_trimmed; alignment length = 90] Allma1 ---------MPHPDPDVYTSTLSKL--QKLPADYAYRTATAALTQQRLAVVDADALEAALPLAFVVKQAEAENQLVDKVAEWKAWEPLAE Ashgo11 ------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------ Aurde31 ERSTEVAAREDERTPETYERTLGLLASGAFPETSVYRQSVETITRRKLEAVDQSTVENAL-IEGALDTAIDELSTAESMAQWKAFDPLEE Batde5 KKTTGLCGLPVHPNSSLYNRILHSL--QQLPEQSAYRQSTHKLVSERLNIVDIAAIEQKIQIEELIYQAEMELKLIPSIEKWKAHEALEV Botbo1 KATTGIHGVAVHPNPKTYESTLSLL--SKIPETSVYRQGAEAITQHRLKLVDISKVETALQIEEVLITAEDELSLAAKMIEWKAWEPLEE Botci1 ------------------------------------------------------------------------------------------ Caeel KKTTGITGLFVNEHPVVYGRILRAL--EQIPRDAAYRKYTEAVVKQRLALVDIKKLEEKIQIEEVIEQAEYELETTRAIVDSKAWEPLVE Canalb1 GVPTGLAGIYKHPNPTLYNETLKTL-KENFPADSVYRQSTEALTQNRLMIVIVENIENQILIEEIVIQAADELSLASQLGGLKVWEELEE Cangl ------------------------------------------------------------------------------------------ Capow KASTGLVGLAVNPSANLYRQTLQVL--GGFPQSAVYRQHAEKLTNHRLSILSDDAAERRIQMEELVRQAEDELALAKKMGEWKAWEKLSV Catan2 KAHTGFTGLVPHPNPELYESTLTKL--NQLPADFPYRTATTALTKQRLELVDVNQLETKIPIEWVIKQAEAENSLVDNMAKWKSWEPLET Cioin KISTGLVGLAVEANPILYNNILSVV--SKIPATASYRKYTEEFANQQLKKLDDVQLEIDLQFEEVIYNAKAELRLARKMISWKPWEGLAV CocheC53 ------------------------------------------------------------------------------------------ Coere1 KVTTGIVGLPVNPTAGLYKKTLDEL-KAKIPEKAVYRQSVEAITTHRLKVADASVIENLVQIEELVCQAEEEINLISKMAEWKAWEPLEE Conco1 KCVSRMRRVPISADPGLYNQTLSVL--SQLPPNAFYKNATQAITQERLNLVDVEEIVRLTQVEQLILEAQDELKLIEEVKETKPWESLEE Conpu1 KTTTGITGLAVHPNPTTYESTLSVL--ASIPATSVYRQGVEALTKHKLSIVDISAAEKQLQVEESINIAKDELTLAQNMLEWKAWEQLEE Copci KQTTGIKGLNVHPNPKTYQTTLSVL--SQIPPTSVYRQGVEALTRQRLKIVDIAAVESQLQIEQSLNIAADELSLANKMLQWKAWEPLEE Croqu1 KTKTDYVGVPVHHSPHTYKTTLKTL--EKFPKGAVYRQSVESLTQVRLEIIRVKDAESELLIEEAIHQAEDEHSLALSIFESQAWQDLQE CryneH991 KASTNITGLAVHPDPSIYTSTLSSL--SQLPAASVYRQAAEALTKHRLAIVDVEKVENELIVEIVIEEAKSEEGLVVKMKDWKSWEGLVE Crypa2 ------------------------------------------------------------------------------------------ Debha1 GNPTGLTGIYQHPNPALYNHTLTVL-DTKFPKESVYKQSVEALTRNRLKVVITENIENKILIEEIIIQAHEELGLANDLSLLKCWEELEE Dekbr2 GNPTGITGILQHPNPSLYQATLKRL-DEQFPKESIYRKSVEELTKARLAVVVIERIEKQILIEELILQANDEYNLAGKMAEWKAWEPLEE Dicdi KKSTGITGLKVEPNAGLYNQLLKKL--EILPPTAGYRKSAELETKFRLGVIDIVKIENKIQIEELIVQAKNDLKVVDLVHESRAWE-LPD Dmel KASTGLTGLAVSTNPALYGKILRAV--SKMPQDASYRKYTEQLVKQRADSVDITALEKAVQVEELIVQAENELILARKMLGWKPWEKLVQ Enthi ------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------ Fomme1 KASTGITGVNVHPNPETYQSTLARV--SEIPQSSVYRQSVEALTQRKLKIVDVAAAEEALQIEEAIGAAQDELNLVGKMIEWKAWEPLEE Fusgr1 ------------------------------------------------------------------------------------------ Galma1 KQTTGIHGLKVHPDPKTYESTLSAL--SSVPQTSVYRQGVEALVRHKLNIVDISVAETQLHIEEALDIAADELSLVAKMVEWKAWEPLEE Ganpr1 KETTGLTGLAVHPNPSLYQKTLSEL--SSIPETALYRQSVSAITSHRLRIVDVSKIEHEIQVEELIQQAQDELGLLEKVKGWKPWEALEV Gloin1 KATTGIFGLAVHPDPKTYNKTLSAL--THIPPTAVYRQATEATTKHRLKIANIQEIEEKIQIEELIVQAEDELKLVAKMEEWKPWESLEV Hisca1 ------------------------------------------------------------------------------------------ Klula1 ------------------------------------------------------------------------------------------ Lacbi2 KRTTGITGLLVHPNPKTYESTLTVL--ASMPQTSVYRQGAEALTRNKLKIVDIGAVEKQLQIEESLDIAADELQLAGNMVKWKAWEPLAE Lenti61 KRSTGIVGLKVHHDPKTYEATLQTL--SAIPQTSVYRQGTEALTLHKLKVLDIAAAEKELQIEESLDIAQDELGVANKMLEWKAWEPLEE Malgl1 KRSTNIAGLEIHPDPSTYTQTLRVL--KTMPESAVFRQSSEAVTQQRLDIVAIDQVVAQLLIEEIVDQAQDELHLAAKMIDWKPYVYLIE Mellp23 ------------------------------------------------------------------------------------------ Mnele RLITGIVGRDVVKDPRLYQTTLKEL--ETLPKSYPYRIETERLTKERMGLLSVVEFEQALCIENVIQEAKSELLLIRKLPNWAPWEPLIG Monbr ------------------------------------------------------------------------------------------ Morel2 KKSTGIYGLPVHPNPSLYNDTLKTL--EQIPAHAVYRQATAALTNHRLSVVDIAKIEQTLQIEEVVVQAVEELKLAGKMLEWKPWEPLET Mucci2 QASTRLAGIPVHQNPQTYNTTLEAL--TRIPTTAVYRQATEALTQQRLSIVNIEEIESKIQIEEVIIQAEEELKMVAKIEEWKAWEPLEV Mydma KVATQLVGISVSKTPDLYSQTLSIL--GSMPASSVYRLQTEEITRKRLETVNVILIEEKIQIEEVIIQAKDELSLAEKIIEFKPWEPLNE Neucr2 ------------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------ Phybl2 KVSTNITGIAVHPTPKTYNNTLQAL--SSFPSTAVYRQATEAFTQQRLAVVNLEEIEAKLQIEEVIIQAEEELKLVGKMAEWKPWEALET Picst3 GYPTGLAGLYQHPNPALYNHTLKVL-DQKYPKESIYKQSVEALTKNRLKIVIVENIENKILIEEIVIQAHEELTLAQELAELKVWEELEE Plicr1 KRTTGITGLPVHPNPKTYEATLQSL--SSIPATSVYRQSVEALTQHKLSIVDISAVEKGLQIEESLDIAKDELKLASHMVEWKAWEPLEE Polpo KKSTGITGLAVQPHADLYQKTLKEL--QRIPPTAFYRQKMEEITKFRYDVIDILKIEQTIQVEELITQAENELQVIDLVAKTKAYE-LSD Pucgr2 KLTTNQTGVDVHHSPKTYQDTLKAL--EKIPASTVYRQAVHSTTRNNLEIIRVKAAENELMIEKAIEQAEDEHQLVLKMIEYKAWQELEE Punst1 KTTTGVTGLHVHSNPHTYQSTLSLL--STIPESSVYRQGVEALTQRKLDIVNIAAVEKELQIEQALDIAKDELSLLSKMIEWKPWEPLEE Rhior3 KPTTGIAGVRVQPNPQTYNQTLEAL--SRLPTTAVYRQATEALTQHRLSIVNVEEIEAKIQIEEIILQAQDELKLVGKMEEWKAWESLET Rhoto1 KLSTGITGLAVHPDPATYTSTLKVL--EQVPASAVYRQSAEAITRERLAVVQIEQVESKLIAEELIQQAEDELKLASKMLEYKPWEDLEE Rozal11 ------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------ Salro RKTTGLVGLKRIVNASVYNDTSAVL--SKFPEASAYRQKMLAITNDRLNLLEIHEFENALQIEEVIDAAEDELSLAKTLAEQKVWEPLAE Schco3 KATTGQTGLEVHRNAYYYNETLSVV--NNMPESSVYRQAVEALTQKKLGILDIATAESQLVIEESIKVAQDELSLAKKILEWKAWEPLEE Schpo1 ------------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------------ Sphar -----------------------------MPSSASYRKHTETITKDRLSTVDPILIENEIQIEEIVLQAKAELSLANKMLNWEAWKPNEH Spipu1 KETTGLYGVPVHPNPSLYQRIIHTA--ERLPAASAYRQSAEALAKHRLAVVDVSAIEQEIQIEELIEQAEDELKLIPKMMDLKPWEPLEE Sporo1 KVATGIAGYPVHPEPETYQGTLTLL--QQIPPSAVYRQSTESITRERLDAVEIEAVEHKILIEEVLEQAQGELQLAGKMIEWKAWEDLEA Stehi1 KTTTGIHGIPVHPNPATYESTLQAL-HSSIPETSVYRQGAEALTLQKLKIVNIEEAEKQLQIEQSLMIAKDELSLVGKMAEWKAWEPLEE Tapde11 YAATGITGLDPVQFPEKYNATLSIL--SQMPASSIYRKATEALTKQRIAIVDVNKIEQEILAEELINSAQDELSLAQKMVLWKPWESLEE Thetr KRTTGIVGLPVAHNAALYAQTLEAL--EALPETAQYRVNVEQMTRTRLDAVSVQELEEMVQVEELIVAAKNELKLIPKIAAGKPWETSKA Treme1 KASTGITGLPAHPDPHIYASTLSLL--SSIPSTSVYRQATQAVTEHNLNIVDVASVERELMVEKLIEAAKEEQNLAGKMLEWKSWEALEE Trire2 ------------------------------------------------------------------------------------------ Umbra1 KSTTGLAGIPVHPNPSTYNATLTAA--SRLPATAVYRQAVESVTQHRLSVVNVNEIEEQLQIEEVILQAEDELKLLAKMEEWKPWENLEV Ustma22 KKSTNITGLNVSGSPSRYTKTLSLL--STLPESSVYRQATTALTQQRLDIVLYERAEQELQLEQVLEQAVAEYRLAAKMIDWKAWEPLEH Walse1 ------------------------------------------------------------------------------------------ Zygro1 ------------------------------------------------------------------------------------------ [Cluster3373.fasta_al_trimmed; alignment length = 58] Allma1 LRSRAIRLYKELLFLGRDYPFRARLKRAFQGKASLTDPVEIEKALAHADYVKREIEAL Ashgo11 ---------------------------------------------------------- Aspfu1 LRRQVINIYKELLYLGREYPFRQRLHKAFSGQAHLTDEEKIRTGIARAQFVKKEIEAM Aurde31 QRLRAIRLYKDLHRLGRDYPFNGRMRKLFEKNRHLEDPDEIEKAIQLGEFIRNETLSL Batde5 ---------------------------------------------------------- Botbo1 YRLRAIRLYKELHRLGREYPFHGKLRRAFEKNRNLEDPEKIERAFALGEYVKNETLAL Botci1 ---------------------------------------------------------- Caeel LRSRVIDLYKNLYHMGKEYPFHDRLKLAFSKNKEVQDSKQVEQLIARGEFVVKEIEAL Canalb1 ---------------------------------------------------------- Cangl ---------------------------------------------------------- Capow MNSTSRRLYKELLFMGRDYPFRERLHRAFAKNRSETDPGKIAELHERARFVIRELEAM Catan2 LRSRVIHAYKELLFLGRDYPFRRKLKSAFQKNAHLTDEHEIKQALLRADFVKKEIEAL Cioin LKHAVKQLYKTLIFIGREYPFRDKCHAAFMKNKDVTDPAEIKMLISRGEYVVKELEAL CocheC53 LRHQVIRIYKDLLYMGREYPFRTRLHKAFASQRHLTDEAKIKQGIERAEYVKKGWSSD Coere1 ---------------------------------------------------------- Conco1 YRHQVLNLYKRLLYLGREYPFRNKLHASFLKNSELKQSEEIEKRIKLGEFVIKEIEAM Conpu1 NRLRVLALYKELHRLGRDY-FHGKLRRMFEKNRNLTDAEEIEKAYNLGEYIKKETLAL Copci TRLRALALYKELHRLGREYPFHGKIRRLYEKNRNLTDKEEIENALRLGEYIKKETLAL Croqu1 LRNRARKVYKELIRLSPQHPLAKKTRECFRSKDQQTKEDEMAKAVAKAQWIRKEIEAL CryneH991 LRLQAIRLYKELHRLGRDYPFNKRLRRAFEKNAKVTDPEAMKKQLELGEHIKKEVLAL Crypa2 LRHEVIAVYKELLNLGREYPFRPRLHKAFMANAGLRDEEAIKKGIERARFVQKGIRWL Debha1 MNSQVRYLYKTLIYMGKDYPFRRQLKAQFV-NSPVRNEQDLAAALAKGEYIIKELESL Dekbr2 ---------------------------------------------------------- Dicdi NRLIVKDLYKQLMYLGRVGFIRDKAKPQFISNANLTDNNKINECIERTKYVIKEIEAM Dmel LRSKVISLYKHLQYLGREYPFRKQIHDAFMNHKDEQDPKKIVALLAQGRYLAKEVEAL Enthi ---------------------------------------------------------- Falba LRSKARILYRELSFIGQHDPFHPQLRQSFAQRAHLTDPKDIQRELRNGERIKRELPVV Fomme1 ARHRVMALYKELHRLGRDYPFHGKLRKMFEKNKELSNPEDIEKALQFGEFIRNETLAL Fusgr1 LRRQVINIYKELLYLGREYPFRPRLHKAFISKAGERDEDKIRKGIAQAEFVKKEIEAL Galma1 TRLRALALYKDLHRLGREYPFHGRMRRLFEKNRHLTDKDEIENALKLGEYIKKETLAL Ganpr1 LRREVRQLYKTFLYLSNDYPLRNVAKRMIMKNRDLRDEGEIRKALDRGNYVVKEIEAL Gloin1 ---------------------------------------------------------- Hisca1 LRHQVIQIYKELLFLGREYPFRERLHRAFASQAHVTDEAKIVDGIRRAEYVKKALSCL Klula1 ---------------------------------------------------------- Lacbi2 TRLRALALYKELHRLGRDYPFHSKLRSLYERNRNLTDPDEIEKALRLAEFIKKETLAL Lenti61 TRLRVIALYKELHRLGRDYPFHRRLRGLFEKNRNLTDPQEIEKAIRLGEYIRNETLAL Malgl1 LRLRSIALFKELHRLGRDYPFIPKLRSAFRKNANLTDPEQIQKLHGLAEFVKK---AL Mellp23 LRNRARKVYKELINLSPHHPLARKTRECFRSQDQQTKEDELARAVAKAQWIRKEVEAL Mnele LRRSVIQLYKELQFMGREYPFNKKCKAAFLKNKDEKDPEKIEMLINRGRFVQKEIEAL Monbr ---------------------------------------------------------- Morel2 TRYRVIALYKQLSYLGREYPFHKKLKGAFMKNKDLTDPSEIQKRIDLGDYVCKEIEAM Mucci2 ---------------------------------------------------------- Mydma TKAKVLQLYRQLLYYGKDYPFKPKLKNAFIKNKHVTDQVELEKLIQRAEYVIKELEAL Neucr2 LRRQVIQLYKELLHMGKEYPFRPRLHRAFMSKSGLRDEGEIKQAIATAQFVQKELQAL Orpsp11 ---------------------------------------------------------- Pench1 LRRQVINVYKELLFLGREYPFRDRLHRAFASQKQITDDEQIRKGIARAEFVKKEVEAL Phybl2 LRPKVIDLYKQLVYLGREYPFRPRLKAAFMKKKDLRDEEDIKKALLHGDYIIKELEAM Picst3 MDPRIRQLYRQLLFMGRDYPFRTQLKRSFE-KTEVVSEEQLQKALAKGDYVVK----- Plicr1 TRLRVLALYKELHRLGRDYPFHGKLRRMFEKNRHLTDQAEIEKAIKLGEYIKNETLAL Polpo TRYIVKNLYKQLLYLGRISFVRNKAKPQFMANAHLTDLNEINQCIERTRYVIKEVEAM Pucgr2 LRHQAVKVYKQLIRLSADYPLAGRTRECFRAEEGAVREEEMAKSIAKAIFIRKEVEAL Punst1 TRHRVIALYKELHRLGRDYPFNHKIRRMFEKNKDLTKAEDIERAINFGEYIRNETLAL Rhior3 ---------------------------------------------------------- Rhoto1 LRFQARRLYKELHYLGREYPFTERLHKCFGAYVG-ADRERIEEGLKKAEFIKKEIEAM Rozal11 ---------------------------------------------------------- Sacce1 ---------------------------------------------------------- Salro MHPAVRELYKRYIFAGKDYPVRRRVKQEFMANKDLKTEEEVLHAVARGRWYFNEFVPA Schco3 TRLRALRLYKELLYLGKEYPFNGKIRRMFEKNRNLTDHEDIEKALKMAEYIKNETLAL Schpo1 ---------------------------------------------------------- Sorma LRRQVIQLYKELLHMGKEYPFRPRLHRAFMSKAGLRDEGEIKQAIATAQFVQKELQAL Sphar ---------------------------------------------------------- Spipu1 LRGQVRSLYKQLLFIGREYPYRARLKAAFLKKRDLSDPEDIRKALRQGEFVLKELEAL Sporo1 ---------------------------------------------------------- Stehi1 NRLRALALYKELHRLGREYPFNGRVRRMFERNRDLHDPEEIEKALKLGEYIKNETLAL Tapde11 SRYKVKALYKTLLFLGRDWPFRPRLHAAFLKSADLKDEKDIANAIHRAEFMVKELETF Thetr ---------------------------------------------------------- Treme1 ------------------SPFNRRLRRAYEKNATEKDPEKLRKQLELAEHIKKEVLAL Trire2 ---------------------------------------------------------- Umbra1 LRSEVIALYKQLVYLGRDYPFRPKLKAAFMKKRDLVDEAEIRKSIAFGNYIIKELEAM Ustma22 MRARAIGLYKELHRLGRDYPFLGKLRSMFERNAHLTDDKEIKAKLDLAEFVKKETETL Walse1 QRYAAIRLYKELHRIGRDYPFHRKLRGMFEKNRHLTDPVEIDKKLAFGEYIKKETLSL Zygro1 ---------------------------------------------------------- [Cluster3375.fasta_al_trimmed; alignment length = 358] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 EPEFEQAYKELASTLLFEKNPEYLAVVSVPERVVQFRVVWEDDNVQINRGYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDNEIRRFCVAFMTELCKHIGADTDVPAGDIGVTGREIGFLFGQYRKIRNGVLTGKGGSWG--GSLIRPEATGYGLVYYVDHMIGKRVAISGSGNVAQFAALKVIELGGSVVSLSDSKGSLVSFTPAEIDIIAQLKGARPWVHVVDVALPSATQNEVSGEEAQALIDAGIAEGSNMGCTQAAIDIFEAHRWYAPGKAANAGGVAVSGLEMAQNSARISWTAEEVDSRLKDIMESCFGSNIAGFTKVAEAM Aurde31 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 EPEFQQALNELSTTLFLAQAPEYLEIVQIPERVIQFRVLWEDDQPQVNNGYRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGIMGGGKGGSDFDPKGKSDNEIRRFCNSFMAELSRHIGKDTDVPAGDIGTGAREIGFFFGAYKKARNGILTGKGASWG--GSFIRPEATGYGLVYFVEHMISTLVSISGSGNVAQYAALKAIELGATVISLSDSKGALVGLTKEIVLEVQELKGKRPWALLVDIALPCATQNEVSGEEAEALINAGVAEGSNMGCTQEAIDVFETSRWYAPGKAANCGGVAVSGLEMAQNSQRLTWTPQDVDSKLAGIMSNCYGANISGFIKVADAM Botci1 EPEFEQAYNELASTLLFEKNPEYLKIVSIPERVIQFRVVWEDDKVQVNRGYRVQFNSALGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLIGGGKGGADFDPKGKSDNEIRRFCVSFMRELSKHIGADTDVPAGDINVGGREIGFLFGAYKAIQNGVLTGKGGSWG--GSLIRPEATGYGLVYYVAHMIGKRVAISGSGNVAQYAALKCIELGATVVSLSDSQGSLIYFTPEDVGKIAELKGSRPWTHVVDVALPCATQNEVSKEEAESLVASGIAEGSNMGCTQEAIDVFEAERWYAPGKAANAGGVAVSGLEMAQNSARISWTQEEVDEKLKDIMKNAFGSNIAGFVKVASAM Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 EPEFQQAYDELVSAVLFKEEPQYIPVVSIPERIIQFRVTWENDKIEVNNGFRVQYNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFNPKNRSDNEIRRFCVSFMRQLARYIGPDTDVPAGDIGVGGREVGFLFGAYKQMRNGVLTGKGLTWG--GSLIRPEATGYGCVYYVEKMIGKRVAISGSGNVAQYAALKVIELGGTVVSLSDSKGSIIGITADQVYAIAAAKGVRPWTKVVDVALPSATQNEVSGEEAKALVDAGIAEGSNMGSTKEAIEVFEANRWYAPGKAANCGGVAVSGLEMAQNSQRVQWTNEEVDAKLKEIMYTCFGANIAGFIKVADAM Cangl EPEFQQAYHEVVSSLLFEKHPKYLPVVSVPERIIQFRVTWENDNQEVATGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGAKGGLCVDLKGRSDNEIRRICYAFMRELHRHIGADTDVPAGDIGVGGREIGYLFGAYRHYTNGVLTGKGLNWG--GSLIRPEATGYGLVYYTQSMIGKRVAISGSGNVAQFAALKVIELGGIVVSLSDSKGCIIGITTEQIASIAEAKGARPWTLVVDIALPCATQNEVSGDEAKALVAAGVAEGSNMGCTPEAIDVFESSRWYAMGKNSNLGGVLTSGLEMAQNSQRMSWTSEEVDQELKKGMVNCFGGNIASFIKVADAM Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin QTEFLQAVDEVLISLLFDRYPKYLPAVCEPERVVQFRVPWQDDKIQINRGFRVQFNQAIGPYKGGLRFHPSVNLSIIKFLGFEQIFKNALTTLMGGGKGGCDFDPKGKTDSEVLRFCQSFMTELFKHIGPDTDVPAGDIGVGGREIGFMFGQYKRITNGVLTGKGWGWG--GSLIRPEATGYGLVYALDFAMGKTVTLSGSGNVAQFAAEKCLELGATVLTFSDSAGTIYGFDSKKLKQLVAIKGKRPWGVKCDVALPSATQNEIEKADADSLVKNGVFEGANMPSNNDAIEVFKNNKVYFPAKAANAGGVAVSGLEMAQNSGRVHWTREEVDNKLKGIMENIYGANAAGFKKVADAM CocheC53 EPEFEQARKELVSTLLFTKNPEYLEVVSIPERIIQFRVVWENDKCQVQKGYRVQFNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGCDFDPKGKSDNEIRKFCVAFMRELNKHIGADTDVPAGDIGVGGREIGYLFGAYRAERNGVLTGKGGSWG--GSLIRPEATGYGLVYYVEHMIGKRVAISGSGNVAQFAALKVIELGGTVISLSDSKGALIGFTPDVINQIAALKGARPWKEVVDVALPSATQNEVSEDEAKALIESGIAEGSNMGCTQEAIEVFEAHRWYAPGKAANAGGVAVSGLEMAQNSQRLSWTAEEVDEKLKGIMKDCFGANVAGFRKVAAAM Coere1 QKEFLQAVDEVFESLVFEKDPGYFERLVEPERQIVFRVPWIDDKQQVNRGFRVQMSSALGPYKGGLRFHPTVNLSVIKFLAFEQTFKNSLTTLMGAGKGGSDFQPRGRSDREVMAFCQSFMTELYRHIGADTDVPAGDINVGGREIGYLFGQYKRMANGVLTGKDLRWG--GSLIRPEATGYGCVYFAKNYLGKRCVISGSGNVAQYTAEKLLQLGAIPITFSDSNGYVHGFTQEQIDHVMELKGKKPWEVLADLAFPSATQNEIDQDDAEMLVSNGVFEGANMPSTNEAIEIYKKSNMFGPAKAANAGGVAVSGLEMAQNSQRLQWTREEVDSQLEKIMKDIFGANIAGFLKVADSM Conco1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci EPEFEQALNELTNSLFLAANPEYLEIIQIPERVLQFRVVWEDDQPQVNNGFRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFDPKGKSDSEIRRFCNAFMMELYRHIGKDTDVPAGDIGTGGREIGFLFGAYKKLRNGMLTGKGLHWG--GSFIRPEATGYGVIYYVEHV----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 EPEFQQAVAEITQTLFLAKNPEYLDVVQIPERVLQFRVTWERDDVAINRGYRVQFNSALGPYKGGLRLHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKTDSEIRRFCYAFMQELSRHIGTDTDVPAGDIGTGGREIGFMFGAYKKYRNGILTGKGADWG--GSHIRPEATGYGLIYYVTEMLGKRVLISGAGNVAQYAALKVIELGGTVLSLSDSTGALIGFTPEEIMDIADIKGKRPWTLVADVALPSASQNELNEEEARALIKAGVAEGSNMGCTLDAIKVFEESRFYAPGKAANCGGVAVSGLEMAQNSQRLKWTHEEVDAKLKAIMINCYGANIAGFVKVANAM Crypa2 EPEFEQAYNELASTLLFQKNPEYLKIVSIPERIIQFRVVWENDKVQVNRGFRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDSEIRRFCVSFMRELQRHIGADTDVPAGDIGTGAREIGYMFGCYRKEKNGVLTGKGLTWG--GSLIRPEATGYGLVYYVGHMLGKRVAISGSGNVAQYAALKCIELGARVVSLSDSKGTLLGFVPEEIDAIAALKGARPWTHVVDVALPCATQNEVSPEEAKVLVEAGIAEGSNMGCTQEAIHIFEETRWYGPGKAANCGGVAVSGLEMAQNSQRLSWTREEVDAKLAGIMKSAFGSNIAGFVKVAEAM Debha1 EPEFQQAYNELVSALLFTEKPEYIPVVSVPERIIQFRVAWENDNVEVNNGYRVQFNSALGPFKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGCDFNPKGRTDSEIRRFCVAFMRQLARYIGSDTDVPAGDIGVGSREVGYMFGAYKQMQNGILTGKGLSWG--GSLIRPEATGYGVVYFVEKMIGKRVAISGSGNVAQYAALKVIELGSTVVSLSDSKGCIIGITPDQIKAIAAAKGVRPWTHCVDVALPSATQNEVSGEEAKALVEAGIAEGSNMGSTKEAIDVFEANRWYAPGKAANCGGVAVSGLEMAQNSQRVTWAAEEVDEKLKNIMYTCFGANITGFIKVADAM Dekbr2 EPEFQQAFNEFVSTILFEKHPEYIPVVSIPERILQFRVTWENDKMQVNHGYRVQFNSALGPYKGGLRLHPTVNLSVLKFLGFEQIFKNALTGLMGGGKGGSDFNPKGKSDAEIRRFCVAFMRQLARYIGQFTDVPAGDIGTGGREIGFMFGAYKQMRNGVLTGKGLSWG--GSLIRPEATGYGLDYYVEKMIGKRVAISGAGNVAQYAALKAIDLGATVVSLSDSKGAIIGITPQQVLDIQAAKGARPWTNVVDIALPCATQNEVSEDEAKALVAAGIAEGSNMGCTREAIDVFEAERWYAPGKAANCGGVAVSGLEMAQNSQRVQWTTEEVDKKLKDIMVTCFGANIAGFVKVADAM Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 EPEFEQAYGELASALLFNEHPEYLAVAAIPERVIQFRIVWEDDKLQVNRGYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGADFDPKGKSDAEIRRFCQSFMTELSKHIGAETDVPAGDIGVGGREIGYLFGAYRKLRNGVLTGKGLSWG--GSLIRPEATGYGLVYYVDYMLGKRVALSGSGNVAQYAALKIIELGGSVVSLSDSKGALVSFTPEQIHNIAALKGARPWVHVVDIALPSATQNEVSKEEAQALLEAGVAEGSNMGCTADAIDVFEAHRWYAPGKASNCGGVAVSGLEMAQNSQRIQWSEKEVDDRLKAIMKDAFGSNIAGFIKVAEAM Galma1 EPEFEQALDELTTSLFLEANPQYLEIVQIPERVLNFRVVWEDDNPQVNRGFRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFDPKGKSDNEIRRFCVAFMGELFRHIGSDTDVPAGDIGTGGREIGFLFGAYKKLKNGMLTGKGLTWG--GSYIRPEATGYGLIYFVEHMISTLVAISGSGNVAQFTALKVIELGATVLSLSDSKGSLIGYTKEFVQKIGELKGVRPWTLIIHIALPGATQNEVSREEAEALVKAGVAEGSNMGCTAEAIDIFEASRWYAPGKASNCGGVAVSGLEMAQNSQRLAWTTQEVDAKLKNIMAECYGANVAGFIKVADAM Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 ---------------------------------------------------------------------------------------------MGGGKGGADFDPKGKSDNEIRKFCSAFMMELSKHIGADIDVPAGDIGVSGREIGFLFGAYKRQRHGVLTGKGLSWG--GSHIRPEATGYGLVYYVQHMIGKRVAISGSGNVAQYAALKVIEFGGTVCSLSDSKGSLISITPEEIYLVQELKGERPWTHVVDVVLPCATQNEVSGPEAQALMDAGIAEGSNMGCTLAAVEHFEASRWYGPGKAANAGGVAVSGLEMAQNAQRLTWTASEVDAKLKQIMKECFGSNITGFMKVAAAM Klula1 EPEFQQAYNEVYNCLLFDKKPVYLPVVSVPERIIQFRVTWENDKQEVATGFRVQFNSAKGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLLGGAKGGLCFDPKGRSDSEIRRVCYAFMKELSRHIGQDVDVPAGDIQVGGREIGYLFGAYRHYKNGVLTGKDLNWG--GSLIRPEATGYGLIYYTEAMIGKRVVISGSGNVAQYAALKCIELGATVLSLSDSKGSVIGITAEHIYAIQDGRGARPWVHVVDVALPCATQNEVSGAEAEHLVANGVAEGSNMGSTQEAIDVFEGVRWYAPGKASNMGGVAVSGLEMAQNSARVSWTRETVDAELKKIMTTCFGANLTGFIRVADAM Lacbi2 EPEYEQALSELQNSLFLAANPDYLEIVQIPERVLQFRVVWEDDQAQVNRGFRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFDPKGKSDGEIRRFCTSFMSELFRHIGQDTDVPAGDIGTGAREIGYLFGAYKKLQNGMLTGKGLAWG--GSFIRPEATGYGLIYYVEHMIETLVAISGSGNVAQFTALKVIELGATVLSLSDSKGSLIGYTKEFIKEIGQLKGKRPWSLLVHVALPGATQNEVSKTEAEDLIKAGVAEGSNMGCTEDAIAVFEASRWYAPGKASNCGGVAVSGLEMAQNSQRLAWTTDQVDQKLKKIMAECYGANVAGFIKVADAM Lenti61 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele QEEFMQAVEEVLVSLLFEKQRDEFNVIAEPERVIKFRVQYPTFGLHTTTGYRVQFNSALGPYKGGLRFHPSVSESIIKFLGFEQIFKNALTNLIGGGKGGCVFDPKGKSDSEVRMLCENFMKGLYRHIGPDLDVPAGDIGVGGREIGYMYGEYVRLRGGVLTGKSTDFG--GSKLRPEATGYGLVYITLEALGLKVLISGSGNVAQFAAEKVMELGGHVCSFSDSTGTISGFSPDQLKELFHLKGKSVWDLGCDVALPCATQNEIKLDGAKNLAAGGVAEGANMPTTNEAVDFLKTKVIYIPAKAANAGGVATSALEMAQNSARLFWTSEEVDEKLKGIMNNIFGANAAGFLKVYKAY Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 EPEFEQAYKELAYTLLFQKHPEYLTVASIPERVIQFRVVWEDDNVQVNRGYRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGADFDPKGKSDAEIRRFCCAFMAELHKHIGADTDVPAGDIGVGGREIGYMFGAYRKAANGVLTGKGLSWG--GSLIRPEATGYGLVYYVGHMLGKRVALSGSGNVAQYAALKLIELGATVVSLSDSKGALVGITVEDINAVMAIKGARPWLHVVDIALPCATQNEVSKEEAEGLLAAGVAEGSNMGCTLEAIEVFENNRWYAPGKAANCGGVAVSGLEMAQNSQRLNWTQAEVDEKLKDIMKNAFGSNIAGFVKVAQAM Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKYCAVSGSGNVAQFAAQKLINLGAVVLSLSDSRGALVPFTLKDIDVIAELKGQRPWKNLVDIALPCATQNENDADDVEALVKAGIAEGSNMGSTDAAVQKMESLRWYAPGKASNAGGVAVSALEMAQNSQRMTWTPERVDTELNNIMTNIF-------------- Pench1 EPEFEQAYKELASTLLFQKKPEYLQVVSVPERVIQFRVVWEDDKVQINRGYRVQFNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKTDNEIRRFCVSFMTELCKHIGADTDVPAGDIGVTGREVGFMFGQYKKIRNGVLTGKGGSWG--GSLIRPEATGYGVVYYVEHMIGKRVAISGSGNVAQYAALKVIELGGSVISLSDSQGALVSFTAEEINTIAEIKGARPWTNIIDVALPSATQNEVSGDEAKALIAAGIAEGSNMGSTQEAIDVFEAHRWYAPGKAANAGGVAVSGLEMAQNSARVNWSREEVDSRLKKIMEDCFGSNIAGFTKVAEAM Phybl2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 EPEFQQAYNELVHALLFTEQPKYIPVVSVPERLIQFRVSWENDKIEVNNGFRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGCDFNPKGRSDAEIRRFCVAFMRQLARYIGSDTDVPAGDIGVGGREIGFLFGAYKQMQNGILTGKGLTWG--GSLIRPEATGYGVVYYVEKMIGKRVAISGSGNVAQYAALKVIELGGTVVSLSDSKGSIIGITQEQIAAIGAAKGVRPWAKVVDIALPSATQNEVSGEEAQALIEAGVAEGSNMGSTKEAIDIFEANRWYAPGKAANCGGVAVSGLEMAQNSQRVQWTAEEVDAKLKNIMYTCFGANIAGFIKVADAM Plicr1 EPEFEQAKNELVTSLFLKANPEYLAVVQIPERILQFRVLWEDDKPQVNTGYRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFNPKGKSDSEIRRFCYAFMGELSRHIGKDTDVPAGDIGTGGREIGFLFGAYKRLRNGVLTGKGLDWG--GSFIRPEATGYGLIYFVQHMISTLVAISGSGNVAQYTALKVIELGATVLSLSDSQGALIGFSKADVEEIAALKGARPWTLLVHIALPSATQNEVSEAEAKALVAAGVAEGSNMGCTQEAIEVFEASRWYAPGKASNAGGVAVSGLEMAQNSQRLNWTPADVDAKLNSIMENCYGANVAGFIKVADAM Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 EPEFEQALGELSESIFLAANPSYFEVVQVPERVIQFRVVWEDDQTQVNRGYRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDNEIRRFCYAFMSELQRHIGADTDVPAGDIGTGAREVAYMFGAYKKLRNGVLTGKGLTWG--GSHIRPEATGYGLIYYVEHMIETLVAISGSGNVAQYTALKVLELGATPLSLSDSKGTLIGFTKEHVEKIAELKGKRPWTLLVHIALPSATQNEVSGEEADALIKAGVAEGSNMGCTPEAIEVFEKSRWYAPGKASNCGGVAVSGLEMAQNSQRLNWTQAEVDAKLKKIMADCYGANVGGFIKVADAM Rhior3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 EPEFEQAVAEIRSTLLFKKRPELFKVLMIPERIIQFRVTWEDDKCQVNNGFRVQFSSVLGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDNEIRRFCVAFMRELSRHIGADTDVPAGDIGVGGREVGFLFGAYKQMRNGVLTGKGYDFG--GSKIRPEATGYGCVYYAEEMIGKRVLISGAGNVAQFAALKVIELGGHVLSLSDSKGALVGLSADFINQVADLKGARPWKLVVDVALPSATQNELDEEDAKALVAAGVAEGANMPCTLEAINVFESSRWYGPGKAANCGGVAVSGLEMAQNSARLQWTDEVVDAKLKDIMKNAFSSSSSGSLSLPLLT Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 EPEFQQAYEEVVSSLLFEQHPEYLPIVSVPERIIQFRVTWENDKQEVAQGYRVQYNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNSLTGLMGGGKGGLCVDLKGRSNNEIRRICYAFMRELSRHIGQDTDVPAGDIGVGGREIGYLFGAYRSYKNGVLTGKGLNWG--GSLIRPEATGYGLVYYTQAMIGKRVTISGSGNVAQYAALKVIELGGTVVSLSDSKGCIIGITSEQVADISSAKGARPWTHVVDIALPCATQNEVSGEEAKALVAQGIAEGSNMGSTPEAIAVFETARWYGPPKAANLGGVAVSGLEMAQNSQRITWTSERVDQELKRIMINCFGANIASFIKVSDAM Salro EKEFLQALEEVIVSLVLTQHPYYLETLAEPEQVHYFRVPWIDDNQQVNRGFRVQYSSALGPFKGGLRFHPSVNLSVVKFLGFEQIFKNSLTGLLGGGKGGSDFDPKNKSDGEVLRFCQSFITSLFHHIGPSQDIPAGDIGVGSREIGYMYGMYKRLTRGTMTGKNTKWG--GSYLRTEATGYGVVYFTDHVMGKTCLISGSGNVAQYCCEKLLQGGAKVVTMSDSSGYIHGMTKEMLQELFDLKGKKPWEVAADVALPCATQNEVTEEDAQTLVKNGLVEGANMPCTSQAVKRIESAGAFGPAKAANAGGVAVSGLEMAQN------------------------------------- Schco3 EPEFEQALTELTLSLFLKANPEYLDIVQIPERIIQFRVVWEDDKPQVNRGFRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFNPKGKSDNEIRRFCVAFMSELSRHIGQDTDVPAGDIGTGAREIGFLFGQYRKMRNGVLTGKGMNWG--GSFIRPEATGYGLIYYVERMISTRVAISGSGNVAQYTALKVIDLGATVVSLSDSRGSLIGFTRDVVQAIMQLKGQRPWTLVVDIALPSATQNEVSGAEAEALVKAGVAEGSNMGCDVEAIEVFEAARWYAPGKASNCGGVAVSGLEMAQNSQRLAWTSEEVDRRLKGIMSDCYGANVAGFVKVADAM Schpo1 EPEFQQAYKEIVGSILFEVHPELLPIISIPERVLEFRVTWEDDKCRVNTGYRVQFNSALGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDNEIRRFSQAFMRQLFRYIGPQTDVPAGDIGVTGFVVMHMFGEYKRLRNGVVTGKHMLTG--GSNIRPEATGYGVVYYVKHMIGKRVAISGSGNVAQYAALKCIQEGAIVKSISDSKGVLIGLVPEEIHEIMALKGARPWTNVIDIALPCATQNEVSGEEAAALIKQGVAEGSNMGSSAEAVEVFEKSRWLAPGKAANAGGVAVSGLEMAQNAQFSTWTHAEVDAKLAGIMQNIFGANIAGFLKVATAM Sorma EPEFEQAYKELAYTLLFQKHPEYLNVASIPERVIQFRVVWEDDHLQVNRGYRVQFNSALGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGADFDPKGKSDAEIRRFCCAFMAELSKHIGADTDVPAGDIGVGSREIGYMFGAYRKAANGVLTGKGLSWG--GSLIRPEATGYGLVYYVGHMLGKRVALSGSGNVAQYAALKLIELGATVVSLSDSKGALIGITVEDVNAIMAIKGARPWLHVVDIALPCATQNEVSKEEAEGLVAAGVAEGSNMGCTLEAIEVFENHRWYAPGKAANCGGVAVSGLEMAQNSQRLNWTQSEVDERLKDIMKNAFGSNIAGFVKVAQAM Sphar EKEFLQAVHEVVEAVFIAENDKYLERMVEPERVIMFRVPWMDDKIQVNRGFRVQFNSAIGPYKGGLRFHPTVNLSILKFLGFEQTFKNSLTTLMGGAKGGADFDPKGKSDNEVMKFCQSFMTELQRHVGANTDVPAGDIGVGGREIGYLFGQYKRLSNGVLTGKAMSWG--GSLIRPEATGYGVVYFTKQMLGKIVGISGSGNVAQYACEKAIELGAKIITMSDSQGYVVGIDTDKLEYVMDLKGQRPWGETMDIAFPCATQNEIDEEEAEALVANGVAEGANMPSTLEAIHVFQKAKLFAPGKASNAGGVATSGLEMSQNSQRYAWSREEVDDKLKDIMAAIHGANIAGFVKVADAM Spipu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 EPEFQRASLDCSAST--EQSPEYFKVLMIPERIITFRVAWEDDKCQVNTGFRVQFSSVLGPYKGGLRLHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDSEIRRFCFSFMKELSRHIGADTDVPAGDIGVGGREVGFLFGAYKQMRNGILTGKGFDFG--GSKIRPEATGYGAVYYLEEMIGKKTLISGSGNVAQYAALKVIELGGVVLSLSDSKGALVGLSSEFIEKVAELKGARPWTLAVDVAIPSATQNEINGDEAKAMVAAGIAEGANMPSTQEAIDVFEGERWYGPGKAANCGGVAVSGLEMAQNSARLQWTEEEVDAKLKNIMQTCFGANVAGFLKVANAA Stehi1 EPEFEQALNELSESLFLSEHPEYFEIVQIPERIVQFRVVWEDDSAQVNRGFRVQYNSALGPYKGGLRLHPSVNLSILKFLGFEQTFKNALTGLMGGGKGGSDFNPKGKSDNEIRRFCNSFMAELSRHIGKDTDVPAGDIGTGGREVGFLFGAYRRARNGILTGKGASWG--GSHIRPEATGYGVIYYVEHMISTRVAISGAGNVAQFTALKVIELGATVVSLSDSKGALIGFSKEVVEAIGELKDKRPWTLVVQIALPSATQNEVSKEEAEALVKAGVAEGSNMGCTAEAIDVFEATRWYAPGKAANCGGVAVSGLEMSQNSQRLTWTPQEVDSKLKGIMTDCFGANVAGFIKVADAM Tapde11 EPEFQQAYNELKSTLLFESHPEYLEIIAIPERIIQFRVVWESDKVMVNRGFRVQYNSTLGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLMGGGKGGADFDPKGKSDNEIRRFCDSFMRELSRHIGDNTDVPAGDIGVGGREVGFLFGAYKRYRNGILTGKGAAFG--GSHIRPEATGYGLVYYVEHMIGKTVAISGSGNVAQYAALKVIELGGTVVSLSDSQGALLGFTSEDVEAIATIKGERPWKHVCIVALPSATQNEVSADEAKALIDSGIAEGSNMGCTQEAIDTFEAARFYAPGKAANAGGVAVSGLEMAQNSARVQWTREEVDSKLATIMENCFGANVAGFMRVAQAM Thetr QPEFFQAVDEVVASVLLKERPELLARMLEPERVLHFRVAWQDDDTEINRGFRVVMNTACGPGKGGLRFHPSVDLSTLKFLAFEQTFKNALTGLLGAAKGGSDFNPRGRSDDEVMRFCQAFMSALYTEIGPDTDVPAGDIGVGAREIGFLYGQYKRLTRGAMTGKGSNWG--GSLVRPEATGYGLVYFARHIVGAKCLVSGSGNVALHAAAKLISLGAKVVTLSDSSGVIHGLTEDGLAFITELKGGKPWQFAGDYAFPCATQNELDGDDAAALVDAGVFEGANMPCTAEAIEAIKSGSMYSPGKASNAGGVGVSGLEMAQNAGHVFWDEEEVDSKLQSIMEDIYGANIAGFERVADAM Treme1 EPEFQQAVNEITVTLFLAKHPEYLEVVQIPERILQFRVTWEKDDLAVNRGYRVQFNSALGPYKGGLRLHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKTDNEIRKFCYAFMQELSRHIGADTDVPAGDIGTGGREIGFMFGAYKKYRNGVLTGKGANWG--GSFIRPEATGYGLVYYVTEMLNKRVLISGAGNVAQYAALKVIQLGGIVLSLSDSTGTLLGFFAADIADIAQIKGKRPWTLVADVALPSATQNEVSGEEAKALLKAGIAEGSNMGCTQEAIDVFEDSRYYAPGKAANCGGVAVSGLEMAQNSQRLKWTPEEVDAKLKEIMINCYGANIAGFVKVANAM Trire2 EPEFEQAYKELASTLLFEEHPEYLAVCSIPERVLQFRVTWEDDKLRVNRGYRVQFNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGADFDPKGKSDNEIRRFCQAFMRELSRHIGADTDVPAGDIGVSGREIGYMFGAYRQARNGVLTGKGLSWA--GSLIRPEATGYGLVYYVEHMLGKRVAISGSGNVAQYAALKCIELGATVVSLSDSNGALVSFQPQHVHAIAALKGARPWIHVVDVALPSATQNEVSLAEAEALVAGGVAEGSNMGCTQEAIDLFEAQRWYAPGKAANCGGVAVSGLEMAQNSQRLAWTEKEVDDKLKDIMKNAFGSNIAGFVKVAEAM Umbra1 EPEFQQAVSELVSCLLFKIHPDLLEVVQVPERVIQFRVVWENDKLQLNRGYRVQFNSTLGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGGKGGSDFDPKGKSDAEIRRFCESFMRELSRHIGPNVDVPAGDIGVGGREVGYMFGAYKKYRNGVLTGKGFDFG--GSYIRPEATGYGLVYYVAHMIGKTVSVSGSGNVAQFAARKVIELGGKVVSFSDSQGTLLGFTNEDIDAIADIKGERPWKHIVDVALPSATQNEVDKADAEALVAGGIAEGSNMGCDLDAIAVFESSRWYGPGKASNCGGVAVSGLEMAQNSQRIHWTPEEVDKKLGDIMKNCFGANIAGFAKVANAM Ustma22 EPEFEQARNELATTLFLEQYPEYFEIVQIPERIIQFRVVWEDDNSQVNRGYRVQFNSALGPYKGGLRLHETVNLSVLKFLGFEQIFKNALTGLIGGGKGGSDFNPKGKSDGEVRRFCKAFATELQRHIGPNTDVPAGDIGFSTREAGFVFGTYKQLRNGVITGKALDWG--GSNIRPEATGYGLIYYVEHMIGKKVVISGSGNVAQYAALKVLELGGTVLSLSDSKGSLIGFTAEMISKIAEIKGARPWKLFYDVALPCATQNELNADEAKFSLSAGVAEGSNMGLDQAAIDVYEQSRWYGPGKAANSGGVAVSGLEMAQNSARLTWSPEEVDQKLKDIMKNAYGANIAGFKKVADAM Walse1 EPEFEQALHEVESTLLFEKQPEYLRVIQVPERVIQFRVPWENDNVEVNVGYRVQFNSALGPYKGGLRLHESVNLSILKFLGFEQIFKNALTGLLGGGKGGSTFSSKGRSDNEIRRFCVSFMTELSKHIGQDTDIPAGDIGTTGREVGFMFGQYKRLRNGILTGKGLSWG--GSLIRPEATGYGVVYYVVEMLGKRTLVSGSGNVAQYAALKVIELGGSVHSLSDSKGSVIGFTPEDIFEIQDLKGARPWTLLVDIALPSATQNEVSGEEAKALLKAGVAEGSNMGSTQEAIDVYESTLWYGPGKAANSGGVAVSGLEMAQNSQRLRWTAQDVDQRLEQIMKDCYGANIAGFLKVADAM Zygro1 EPEFQQAHDEVVASLLFKEAPKYLPIIAVPERIIQFRVAWEKDNQEVATGFRIQYNSAKGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLMGGAKGGLCVDLKGRSNSEIRRICYSFMRELSRHIGPDTDVPAGDIGVGGREVGYLFGAYRQYQNGILTGKGLNWG--GSLIRPEATGYGVIYFAEAMIGKRVVISGSGNVAQYAALKVIELGGTVVSLSDSKGSVIGVTAEQIAAIQEAKGARPWTHVVDIALPCATQNEVSGDEAEHLIKSGVAEGSNMGCTQEAVHAFENTRWYVGGKASNLGGVLVSGLEMAQNSQRLTWTAADVDKELKRGMINCFGANLAAFIKVADAM [Cluster3377.fasta_al_trimmed; alignment length = 119] Allma1 LLTTASKKPVGAIRGGVIGFLLGIVLAGTAGYYYLVDDYQVYSNALLNNVQLGGSVESIRASLKKADKLETEVKALKDNAAKR-DELEKARKELLKALDNLTIEHLELKTRVWAAEQDI Ashgo11 ----------------------------------------------------------------------------------------------------------------------- Aspfu1 ----------------------------------------------------------------------------------------------------------------------- Aurde31 SFATSRKRPVGGFRGGIIGFLAGFSVASGVAAYQLLEEYKVASAALQASIQLQANTEKVSSHIRRIEAVESELNALAASSATK-EEQSRVRAELKKAQDGLRLEFLDLKAHVWGIQQDL Batde5 LLSTEAVRQVGYVRGGMFGFLLGVTVSSGVAYGYLLDDYQQSTTSLLAGVNVQLSANKIKSQTSKIEVLEKELKSATKSYSTK-KEFENLRNELLKAIDDVHVSHLELKTQVWE----- Botbo1 SLYSSAKRPVGAVRGGIFGFLLGFSLAASFASYHLLEEYKQASATLQASVELQSSTQKVSEHVKRIEAVEKDLKALADSTAAK-EDVSKLRAELKKTYDGLHLEFLDLRAHVWGMQQDL Botci1 GFSMSARKPVGAFRGGLTGFLLGSTLAGAGVYYYILEEYKVSNELLTEDISLQNSVQRVHTYVQSLE-----------------EKLADL----------------------------- Caeel ----------------------------------------------------------------------------------------------------------------------- Canalb1 SYSTTTRKKVGAFRGGFIGFLLGVTTTGGLSYYYLLDQYKLANTVVIADIALQNSITNLEKHIKSLE---------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------- Capow ALSTSAKKTTGRVRATVFGFLTGFVASGVFAYYYLMEDVNKSARSLRRKMELQRSTEKVALSLQKIHTLERELQSLKNSAALA-EDVRALRNDFESSSNALQVSITTQNAQNYETHNAI Catan2 SLSTETKKPVGAVRGGIMGMLFGFVVAGATGYYFLLDDYSVYSNALLTNVELGSSVESIRSRLAKIDSIESAVKSLKSTAIHH-DDLDKAKRDLYKSLDAMTVEHLELKTRVWALEQEL Cioin ----------------------------------------------------------------------------------------------------------------------- CocheC53 AFQTSAKKPVGAFRGGLFGFLLGATTSGAGMYYYVIDEYRVSNQLLTEDIALQSAVQRIEGYVRTLE-----------------EKVD------------------------------- Coere1 ----------------LVGFLLGVTSAGAFGFVYLIEEYQKATGLVLSSVELEKSSLKVKEYVKKIEAVESDLAKVRANSATI-QQLAQAKADWRKQSDILTRDHLELKAHVWEIEQDV Conco1 RFNST-QPRMGGFRGGLIGFLVGATVAGSTGYYFLIHDYQVATGLLLHSIELQLSADKVREYARQIESVANEIAKLKDSTAKI-DQIDRLKGDIRKLYDSVGVEVLDLKGQLTDLEKDV Conpu1 FISTSRKKPVGGFRGGIIGFLFGFSLASSFAAYSLLDEYKRASAALQASVELQVSTEKVSSHVRRIEAVEKDLKALSSGSASK-EDLSRVRAELKKVYDGLHIEFLDLRSHVWGMQQDL Copci GFSSTTKKPIGGFRGGIVGFLFGFSLASSLAAYHLLEEYQRASAALQASVELKISTEKVSSHVRRIEAVEKDLKALSSASASK-EDISKVRAEVKKLYDGLHIEFLDLRSHVWGIQQDL Croqu1 ------TRPIGGIRAGFVGFLLGLAVTGSYASLHLFEEYQAASNALLLSVELKANTSKITNQVKRIERVEREVQRIDGQAVTG-EQLGSTESKLKKLLDGLEIKQLKLEAKVSDLEIDC CryneH991 QLSTTAKRPVGGFR--ILGFFFGFAFASSLSIYYLQQETKLATGLLTASIELQQGTGNITSHLDRLQTVEKELATLKANNALK-EDVTKVRGEMKKVYDGLHLELLDLRAHVWGVEQDL Crypa2 AFASTSRKPLGAFRGGLFGFLLGATLAGSGSYYYILQDYKASNELLQDDIALQAATQRMSNYLTTLE-----------------EKIDTM----------------------------- Debha1 SYSTVA-RKVGAFRGGFLGFLVGVTVTGAGSYYYLLEEYKQANNVVVADVALQSSINNLEKHVKLLE---------------------------------------------------- Dekbr2 FFNTKRRSP--SAKGVFLGFFAGASISGIACYYYIMEEYKATSSAVVSDVRLQKAVEKLDKHVTDVE---------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------- Fomme1 SFSSSAKQPVGGFRGGIVGFLLGFSIASSFAAYHLLEEYKQASAALQASVELQASTEKVTAHIRRIEAVEKDLKALSNTTATK-DDLSRVRAEMKKIYDGLDIEFLNLRQHVWGIQQDL Fusgr1 TFSTSARKPLGAFRGGLFGFLLGSFLSGSAAYSYLLKEYKTANDLLTEDITLQASITRLSNHVQALE-----------------TRM-------------------------------- Galma1 SVSSTSKKPIGGFRGGIVGFLFGFSLASSFAAYHLLEEYQKASAALQASVELKLSTEKVSAHVRRIEAVEKDLKALSDASATK-DDVSRVRIEVKKLYDGLHAEFLDLRAHVWGIQQDL Ganpr1 ----------MAFRGGVLGFFLGVSVAAASGYSYLLSDYNHATGTVVKSVDLQKSTNKLRDSHLAIDNVAAELKSLRGDAATR-EELARLRGEVIKAGDSAQSAILALRTELWDLQQDV Gloin1 SFTSTNRKPIGGFRGGLIGFLVGLTIAGGAGYHYLLDEYNTASKLLLSSVELQKSTNKVRDYTRKIERVELELKALQMSAATI-DQIKELRGEVRQLYDSLHIEDLELKAYIYGIEQDV Hisca1 PFSTTSQKPVGAFRGGLFGFLFGTAVAGTSVYYYILDEYRVSNEMLTEDIALQAATKRLNAYVTDLE-----------------TKMDQL----------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------- Lacbi2 --TSESKKPIGGFRGGIVGFLFGFSLASSFAAYHLLEEYQKASAALHESVELKLSTEKVSAHVRRIEAVEKDLKALSDASASK-DDISRFRAEVKKLYDGLNVDFLDLRSHVWGIQQDV Lenti61 LLSTTRKKPVGAFRGGIVGFLFGFSLASSLAAYHLLEEYKLASAALQASVELQASTQKVSAHVRRIEAVEKELKALSETSATK-EDISRVRAEMKKLYDGLHVEFLDLRAHVWGVQQDL Malgl1 ----------------------------------------------------------------------------------------------------------------------- Mellp23 -FSSTTNPSSGKLRNGVLGFLLGLTLTGTYLTSQLYQDYQTASNALQLSIELKSSTLKITNQIKRIERIERDLDALNNSTNQSINKIQNTTSSTSQTLDKLEIQQLKLSSKLSQLEIDC Mnele ----------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------- Morel2 ----------------ILGFLIGATAAGGAGYYYLLEEYQTASNLLLSSVDLQASTNKVRDYAKKIESVEAELKTLKSKTATV-EQLSELKSEVKKVYDGLNIEHLELKSHVWGLEMDL Mucci2 --------------GRVIGFLLGVTAAGSAGYYYLLGEYNNASAALLLSVELQASTDKVKDYAKRIETVDRDVAKLKETTATK-QQLADMKVDFRKLYDTLNIEHLELKTHVWGLGRKK Mydma ----------------------------------------------------------------------------------------------------------------------- Neucr2 GFQTSARKPVGAFRGGLFGFFFGSTLAGSAVYYYALQEYKASNDLLTEDIALQNAVDRLSKYLVTLE-----------------EKMEAL----------------------------- Orpsp11 ----------------------------------------------------------------------------------------------------------------------- Pench1 SFSSSRSKPVGAFRGGVFGFLAGSVAASASVYYYILAEYRFANEMLSDDIALQKATIKLQSYITELE-----------------TKVDQL----------------------------- Phybl2 ------KETKGGFSSGLTGFLVGVSITGAIGYYYLLEEYTAASNSLLKSVQLETTTKKVRDYAHKIESVEKDVNRLKETVATV-QQLSELKSEIRRVYDTLNIDHLELKTHVWGLEQDL Picst3 ----------------------------------------------------------------------------------------------------------------------- Plicr1 SFSNTLKKPVGGFRGGIVGFLFGFSLASSFAAYHLLDEYKQASAALQASVELQLSTEKVSAHVRRIEAVEKDLKALSETTAGK-EDVSRLRAEMKKIYDGLHVEFLDLRSHVWGIQQDV Polpo ----------------------------------------------------------------------------------------------------------------------- Pucgr2 PFSSTLNRPIGGIRAGILGFLTGLTVTGSYAYLHLFEEYQNACNILLLSVELKASTLKITNQVKRIEQVEKDLNRIESSTVTE-DQIKKLKSELKKLVDRVQIEQLELKSNLTNLETDL Punst1 WISTTRRKPVGAFRGGIVGFLFGFSLAASYAAYHLLDEYKLASAALQASVELHASTEKISAQIRRIEAVEKDLKALSGTSASK-EDLSKIRAEVKKLYDGLHVEFLDLRSHVWGIQQDV Rhior3 FYSTS-TPKVSPVRGSIIGFLLGVTTAGSAGYYYLLDEYNSAASALLTSLELQVSTEKVLVFML------------------------------------------------------- Rhoto1 FVSTSSRRPVGAFRGGLIGFLLGVSLVGGYGYFRLLDDYKQASSALLLSVELKRSTTQMSTHLSRISSLESAISKLESSSATK-KQVDSLRGEYTKLFESEHLEVLNLRAHVWGIEQDL Rozal11 SYSKTITKSGSRLRSGLFGFLFGSSLTLFTGIAYLSNDVNDSLKSLNNSINVENTTFQIKDQYKKLNTLEERLNDLEDSSIDK-KALAILRREMSDHIDFLSIENKKLQNQVFELEKLL Sacce1 ----------------------------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------------------------- Schco3 SFSTTHQRPVGGIRGGIIGFLFGFSLAASFAAYNLLDEYKQASAALQASVELKLSTEKVTEHVRRIEAVEKDLKILEKSSASK-DDISRVRAEMKKLVDGLHVEFLDLRAHVWGMQQDL Schpo1 ----------------------------------------------------------------------------------------------------------------------- Sorma GFQTSARKPVGAFRGGLFGFFFGSTLAGGAVYYYALQEYKASNELLTEDIALQNAVDRLSKYLITLE-----------------EKMEVL----------------------------- Sphar A-------------KVLLSFVLGASSAGGVGFFFLREDMKASNRFVSKRVEMKHMVGELEDTMGGLRRLQDEVAEMKRNTATL-EDFTTFKIEQEKQITQLTASLAEHKSKVWETQQAM Spipu1 RFNTTERSGGGFFRGGIIGFLLGITLAGATSYVYLLDEYQQSSNALLSNVDLAKSTAKLRDHTQKITTLEKDLNGFTQKAATK-GDLQALRNELLKLIDEVNVSHLELKTHVWEIEQDV Sporo1 SASTSTKQPVGAFRGGLIGFLLGLTALGSYGYFLLLNDYSVASRQLVESVNLESSTTLISNQLEKISKLESKLDALERTRVAR-KQLDDLRSEYKQLSESQHLDLINLKAHVWSIEQDL Stehi1 SLHTSRKKPVGGIRGGVIGFLFGFSLASSYAAYQLLDEYKQASAALQASVELQRSTEKVSAHVRRIEAVEKDLKALSESSSSK-DDLQRLRAEVKKIYDGLHIEFLDLRSFVWGIQQDV Tapde11 TLSTARKRSIGGFRGGITGFLLGMAVSGTLGYSYLLQEYQNASNLLLSSVELQASTSRITGYVKRIEDVESSLRKVQKGSATQ-NDHSTLRKEMHKVYSGLNVEQLDLRSKIVELEKDL Thetr ----------------------------------------------------------------------------------------------------------------------- Treme1 AFSSTPRRP-----------FFGFSAATSLGLYYLQQENKVATGLLMASVELQQGASKITSHLDRLQTVEKEIASLKTSTAVK-DDVSKVREEMKKVYDGLHIELLDLRAHVWGVEQDL Trire2 GFHASARKPMGAFRGGLFGFLFGSVLAGGAVYSYVLQEYRASNELLTEDITLQASVTRLTNHIKLLE-----------------DKI-------------------------------- Umbra1 ----------GAVRGGLLGFLLGVTISGGVGYYYLLEEYNTASATLLSSVDLQASTEKVRDYARRIESIDRDLSKLKETTATT-QQLQDLRVELKKLYDALNIEHLELKTHVWGLEQDI Ustma22 RFASTQRRPVGSVRGGVLGFLFGFGIASAYGYYYLLKEYNAASNLMLASVELQGSTEKITGHLQRLNKLEADLKSLTSQTASK-AEYEKNRLEMKKIVDGIHDEVLDVKKQVLDLPRPT Walse1 -MSTST-RPIGGFRGGLLGFSAGFVAASLGSYFYLIDDYRKSNESIATTVSVSKESVELGKKFSRIDALEDDFDSLKSSIK---DEIDLKSQRTQSEVQQLQSEVSDLRTYIVSLEQDI Zygro1 ----------------------------------------------------------------------------------------------------------------------- [Cluster3390.fasta_al_trimmed; alignment length = 480] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 Q-PYLELRERLSQIWINRYTLLLMLCMVKILLFTSSLLNNSKVHVLEECSNIEHYYNILRNGTPHYMGKMGNYLVAHALEATVESLLALLTSLATVVEVVAHFMIELWLGTYACLLFSAAHGAVEVATNVTEKVIGVANKTLIAAANEL-DNGLDGLS-KVLNKIIEK-KINIASLRT-VK-I-PES-VNDKLRSLAE-K-TPDFEDVKN-KTKGL-VSIPFQTLKNEINRKLMSVPVC--SANRSVYRNLNSALIYSLVATAVSLAIVALLCLIPAAWHEYRQWERLSALRDH--IQWLLAYVLSPRALVPLALGLAGVLVCGCQFLIIQRLETDTAGLVAHDLSADSTNAYINGTEASVNAGLLG-WVTTATTALNTTVAALLADIDSTVDRAFADT-P--LHRPMVTVVSCVIGNKLRAIEAGLTWTHDHVR-IALPRIHTAVDRVLHQCCA-AVRIELYVSLALLGLWILQTPLGL Aspfu1 T-PYLGLRARLSQVWINRWTILLLLVLVRVLLAASGLMSTAKREALSACTSVESM-GSSMASMPHYLSQGVNELTATGVEKAVSGLKSMLMLTITGVEELVLFIIKVLYQTYLCLFTLAVRGSVHVAVGVIKEAADFLNSTVKEVGDDI-GKAVSTFE-SAFNKFLDP-TLDISTLEN-LQ-L-PSS-IDQGLDKLNS-S-LPTFDEVNN-FTQTV-LRTPFEEVKKLVDRSLLPVPFC--EGSNSFFDSVTDLVMKARKIFIAILIVAATLACVPMAWQEIRRWRSMKERSQLVRVRWAIAYATTPAALFVLCLGVAGLLSCLCQYLLLGAFADKVVDSLQNASAANDANGVIGHMSQDLNENVFG-WVNTSTTALNDTLNTFVDKTTGVLNDTFGGT-L--LYEPLMDVFGCLIGLKVQGIQKGLTWVHDHAH-IDFPLLPNDVIRVVNKVED-GIRTETIISGVIILIWVFIALIGI Aurde31 K-PFLTLPQLFSLTWLAYPVLSLLFVAFRLQISSADAVADAKFSLLTSCKAAETA-ATGAASLPRFLAQGTNAQIVDAVNGTLNAARATLILALTIMEAIIEFIVDMYRSTFLCFLELVVRGGLSILIAASEEITKFLQNTLGAVANSI-RNDVSAAN-NAINKAIDP-QVTLDALEN-IK-I-PND-FTNALISLNS-T-LPTLDELRD-AIDKV-IEVPFEGLKREIDASVLPVPFC--ADLDSVVDRLGVDLLQVTKIATILLVVLALLLIAANCLVEWYKYRCLQASLERTRIRWFFSYVFHPPALACLLIGLFGLISVELQIAALSNIAASINDSMRNESTATAVNGQVDGIQSTVNDGMFG-WVNGTTSTLNDTLVTFYAEVQNTVETVFGGT-I--LEGPVQEFVRCLLGTKVQAFENALTFLHDNLH-IDVPRVSDDVGRLITRYVA-SLKKERIMFLIFLGLWGFVVLIAL Batde5 K-PYLGRTAKLSRAYANHIVLALALVLCSLIVLSTYIANTAKRVLAQACTGLETA-TNALALTPRFTAIALNRVTTIAMHNAIDQVGRLAHAALILVKQLMLYILFRYQRVILCALQLTVMSATNAVSSHAQQITNFLNTQLKDISGTL-AAGLNGIN-SQIQNVDSP-QIGVSDKLNGLQ-L-PAS-FQQTLQGLSA-S-IPTLDDIEA-KISGV-LSGPFDDVSNKIDQGIFPVMFCYGNAYNGWIDRISEAITVALWYGCLGIVLAMMGVTACYMFWILWEHRLHEQNVARIQLMWSMQYVAHPFSLLCIAFGTTGLIVVRFQIYLLDFILGRIASAVDAVVGISKVNTDINAIETQVNTVMIG-WANDTIATAEVGIETVMTGFNDALNNLFEAV-P-GIKTAVISFTTCVIGNHTAMLRSIQNSLANGVV-ISLPRANASLTWMQTEYEK-TLWLQMLPFWVALILGLSIVIFAI Botbo1 A-PYLTLPYLLSLTWLATPIVSLLFVAFRLSTSADSAVGDTKANLLASCAAAEQA-ATVAASLPRYMAAGTNRQIIEAVNGTMDVTRKTLVFLLTIVEAIIEFVVDTYRSTFLCFLELVVRGGLAIIIGAVQEISAAVTSSLNTIRSSI-QNDVAAAN-SVISSAVSP-QFTLTLLQN-VT-I-PAD-FENSLLKLNS-S-LPTLSELRD-AVNSI-IETPFTALKVDINESLLTVPFC--QDMDSIVDDLGRDIVKITKIGVGLLVLLAFLMVLANCFVQWWQWRCMKVNLQRTRLRWFCAYVFHMPALTCLLIGLLGILSVQIQLAAINSIADNINTSMRNQSAVNGVNGHSIALQTSINNNLFG-WVNGTTTALNNTLVTVYADIQKIVNTTFGGT-V--LDAPAQEFVRCILGSKIEGLEKALTFLNENLK-VSVPTLSPDVGRIVDRYVA-ALKKERLMFLIFLGLWGLVVLMAL Botci1 T-PYLGLRARLSQTWINRWTVLLLLIIVRLLISLAGIVASAKTEALSACSSVENV-GSAMASMPHYLSQGVNSMAAAGITKAVNGMMQMLYMSLTGVEEIVLFVIHMMTSTYMCLITLAITGSLQVAIQMIEDVGAFMNKSIDTITGDM-SSGLKSFE-DDLNGFLSP-TIDINKLNS-IQ-IDPTT-MDADLAKLNA-S-LPTFEQVQN-FTDNI-IKLPFEEVKKLVDDSVFPVPFC--SDNTDFFVGLVKTLDTAKKIILIVLVIAAILACIPMAFREIWGWRVMQIQAALLKARWFIAYATSIPALFVLALGLAGLFTCLCQFIVLGDFAEHVVKALNNASEALGANSVINNTNTEINDNVFG-WVNTTTGAINETLNVFTDEMTKALNVTFGGT-I--LYKPIMGVFECLVGLKIAGIEKGLTWVSDNAH-VEFPEFQPDVVKVGKKLEA-VIRQEALISTALVAIYFVIVLIGL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 R-NYLNLPEILTQVYLNKYAILLILILIKLILLETSILNSV-LLDNSICDNGEI----------QPVLNTVHYMIVDSLQTLEAAGIVSIILTLKVIKQLALFFIELFFGTYICLLNAALKGSTEVALDASEGVIRAVNATVVSATNDI-ESALKGLS-SIINDLVTN-KINLGDLKSKIM-I-PSE-VLTKLDNFKN-SSLYGLSQLGN-GTQTI-VSTPFELAIKKL-----APSEC--LKDMDVQTDLAKLVEKISKWLFIGLVLAMVGSILYVSYIQWRHWRRMDKFISETGTIWMLSFMFSKISRNVFFFGIMGVVSVVAQYILLTSNSTSM-----SASTLRDMNTYIDDTQDKLNQELFS-GIKEISVSLNSTIVEFLDKLNETLSDIFGST-P--LAGPINTVVYCTIGRKLEKVEKGLTWMNDNLN-INIPSISRDANKIIDLYRK-SILLELYISLGLLGVWLFQIFVG- Cangl R-NYLLLRDRLTQVWLNKYSITVTILTAKIVLFNYFILRYTEKYAISSCNGLDQVNRKVYDDLPIFVNTLGNYMIRKSMLESVEASLRGLEILIDASEGLLGFLVDLYLGTYACLLISAVDGAVDVATNTTEHILEAVNNTLIEATRGL-DDGLNDLT-SLINK---S-KVNVKGLRN-IH-L-SSK-INDQLQYMAD-K-VPSFDDLKS-ETKDL-ISIPFYHVKREIDTKILYL-IC--GQYIKVYEHLIHILKVGNILVAILGIFIALFMAIPSIQKEYQESKRLNNVQDEVSLQFCMLYIFSSRSSTIMAMGLIGLITVAIQLIVIQASNDEINKMIKSDINTSLANQYVNGTEANLNTQVFG-WITNTTASVNATVAHAVDKIEYILASSFNNT-P--LYKPMKTVVGCAILRKLISVENAMTWINNEAH-IKLPRINTTVEKIVNIARK-TALNELYVPLALIGIWLTQIPMAL Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 K-PYLGLRARLSQIWINRWTILLLLILVRLLIAVASTLVSARREALSACTQVEKI-GSSIASMPHYMSSGLNEMTASGVEKAVSGLMTMLEMTVTGVEEIVLFVIHMMTSTYLCLITLAVSGSLHAAVEISEAVTKKLNETINSVTEDM-GDAVKSVS-DGINSIMDP-TINITQLKA-LE-L-PPD-MTEGLKKLNQ-S-IPTFTEVQN-FTDNI-IRTPFEEVKKLINRSVLPVPFC--SDGNNFFDDLIVLAYNARKIALGVLIVAAVLVCAPMAWMEMRRYRKMQERAALF-MRWAWAYATSVPMLFLLSLGLAGLLSCFGQYLLLADFAGKVVSSLNNASMSNGVNSAVGNLDSKINDDISS-WVNTSTTAVNDTLNAFVDQMSTTLNDTFGGT-V--LYDPIKEVLNCLIGLKIASFQSGLTWVQEHAH-VQFPGVANDVERVIAKLMS-GIQTEALISSALVLVWLLTAIGGL Coere1 M-PYIGKWAQLSRSWASQTVIMLLFMGVGYILMASLAAEDAAALLIAACNAVDAA-SDAVINAPNNAALSTLRMVEKSAENIIEFTAKTLTKIIDIFENMIVWVLKLYIGTYICFAELIIRTALSMVAQAGKIITDELNKAIDGVVGTL-QDVSAKIA-QGAND---D-AIDIRKKLD-VH-I-PDD-WVNSIKSLED-K-IPTEEQIFG-NVTKL-LDIPFNIIRKALDKVHLETDVC-AHPMGDLLVEVGEGAAMVMFIAGVALIGAGIGLIIFKAVMAWLRESRFRERLGEFRWRWWLHYVWHPPAMACFIAGLFGLIAIIVQINAIYAIDQGVIGGVHNDSAADTINKSVNGSEEDLNNSLFA-PVTEGTESLNKTLDDFVKKYINGIRDVFGGT-P--LEQPIEGLVNCTLTKNIQAIQKVLTYLNDFTKGIHLPRVEQDIGRLCDSYIS-NLKSQIPLMIALMLVWIVIAIIGG Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 --------------------------------------------------------------MPRYMAIATNQQFADAANGTMNGARAALVLALTCMEAIINFLIDIYRSTFLCFLDLVVSGGLSLLISAVQEVQSFLQNTINGIVSGL-VSDANSVN-SAIQSAVNP-QFNLSQLQN-IT-I-PND-FENALIKLNS-S-LPTLSSIKD-AIQGL-VDTPFEAVKQDIDPTLFPIPFC--DSLDSSVDNLGQDLLKAAEIGTIILAVAALVLLAGFSVLEWYKWRCLQFHLSNTRLRWFLHYIFHPPALACFLIGFFGILSVELQLLAVSTIAAQMNASMYNQSSASGINLQVASVQNTINQGVFG-WVNGTTTTLNATLNSFYADVTGAVTSVFNGT-I--LENPALDFVNCLIGSKVEALEDALTFLNENLN-VDLPRVNESIARLVATYVD-SLLKERIMFAVFLGLWGVVVVMGL Copci T-SYLQLPHLLSLTWLAYPILSLIFVAFRLQASLASSISSAKSNLLASCKAAEEA-ATSTASLPRYMAIATNQQVADAVNATLRGARAALILTLTVMEAIINFIIDLYRSIFLCFLELVVRGGIAILVGAVEEINNVLATVTSGLRTQI-QASVGTLN-NALRETIEP-TFDLDGLDN-VS-L-PDS-FQESLLRLND-T-IPTVSTIKE-KLQDI-IGTPFELVKRDISADTLPVPFC--SDLDSVVDDVGNDIVKSAKIGIVILLVIALVLIGLNCLFTWYKWRCMQAHLEYTRMQWFFNYIFHPPAAACLLIGVFGLLLIEIQLLAMLLIANSINESMLNQSTAAEINGRVDSVQTTINDGLFG-WVDGTIVPLNTTINEFYDDIQNAVQTVFGGT-I--LETAATEFIRCLIGSKVDAVENALTFLHENLR-VDMPRVNDTIGRLVNSYAD-SLRKERVTFGIFLALWGVVVLMGL Croqu1 M-PYLGLRARISLAWLAYPIMIIILIMIQLILTLSSVVADAKRNLAASCAGFEGA-ASVAASIPHFMAEQTNEFIVSGAESIVHGLAVVLDIAIHAIEAIILYVVDTYRSLYQCLAEFVVRGSLALLISAAEEAEKVFAEAVSGLRTALPEATIGGAE-SIVKDAINP-DLRLAALQN-FK-V-PTG-LSDALTQLNS-S-LPTLQELRD-ALDKV-ISTPFEALRAEVDRTLLKAPFC--QDLDSFLDKVGKIISAGLRIIILILLVAIIVIFLFNVVRERFFYKRMVKKVDEARLPWFLAYITWPSALLFLGVGLLGLLVVEVQLFALNLLADKINSQTANISAAEDTNSVIIRFQSDVNDHMLG-WAGTTTTTLNNTLTTFYDGLTTVVQGTFGKT-P--LKDAALGLLNCLIGSKVAGIQSALTFVHDHAH-VDLPTVSPTVDRLIDRYTK-VLHKQRITYIALLGCYLVVIIFSV CryneH991 Q-PYLSLLPRILLTFFSPCLLPMILTIAHLIQNRSSTATSLKSSVLSACSGLAKG-AASIKTLPRYLATQTNQEAIRATQASILAIGTMLMDAITIIEAVVNFIVDTYRSMLLCTIELAVRGTLEILISAVQNISDGITDTLNSVRSNI-QDDIGDAN-DIIQTAVNP-EFSLSFLEN-VT-I-PTT-FEDSLITLNS-S-LPTLAELKK-KMNEI-IDTPFEALISEINSSILPVPLC--SDLDSLIDDTAKALHKLSNIAIGLMFLLLFLVWAVLAVWEWRKWKLMKDTVDAIELRWFLSYLAHPTCLALLFISLLGLLSIQFQLVALNSLVTKLNAAALNSSQADSYNKAIAGYQDRINNGLFGSWVNTTAVILNSTLVEFYDEVENALNASFGGT-I--LYNPINTFIYCILGSKITNLEKGLTWISEHAF-VDLPTFPSDVGTLISHFES-ALKVERTFYGIMLGVWLALFLIGL Crypa2 T-PYLGLRARLSQVPINRWTVLLLLVLVRMLILFAQLLVSAQQEATAACSKVEDI-GSTLASMPHYLSAGVNKLVAGGVTDTVRGLVKLLIMIVNAVMQTIMFFINFEYGTIACVADDFIHGLITVASDTIGALLKELSEGLKDIANGL-SSAV-----SGVDDAIKP-DLDIASLKN-YQGIDANQ-TVAAINRFNQ-T-VPDFDQLET-DVQSV-INIPFKAVELLLDPSVFPTAFC--TGNDQFFEALFTVVKDAKTIAIVSLILAAILAAVVMAWWEVKRYHRSVAMAQ-TTIRWCIAYATTYTALFVLSLAVAGALSVLCQFLVMGGFVTEVIDRLEGISTANESNQAIASFQDDINGKVLV-YVSNATDAVVNVINVFENKTEQILGEAL-GT-VPQLENFANGLLDCILIDKLDEVKDGMEWIHQHAQ-VSFPAFPTDVDKVVTALRT-SIITEGLIALVLMLIYIAYVFFAV Debha1 K-QFLNYYEILSQVWFNKYTIILVLMTIKIYLFTNSILTNFKAYTESICTSLDTY-STVIASLPEQLSKVINHMVASTLNSMKMQSLKMLMTIITIIKLLIVFYIDIFLGTYICILTAAIGGTVDFALDSTQLVLKSVNETIISVSEDI-QDGLNGLL-KVINTLLSD-KVNIKALQN-IK-I-PNS-VLTDIDNFKD-K-VPDFNELQN--TSKL-VSKPFEIITQELQLKLASTP-C--S-NSKFYSNLAKKVQFTSNIIIIVLLIMAMFAIASLVVVEYFKWRKSQRMINEILLYWLLSYITTPYSLTVLIIGLAGLFTVMLQFIILTGFKTQIITLMDNATSIKETNSYIGSQQKLINDELFG-NIRTASTSVNSTINDFLMKMNTTINSVFANT-P--FSKPVNTLVYCTIGRKLIKIEQGLTWIVENLS-VSLPQLPKNITFLLDTYKK-SLLIELYISSAILGIWILQIIIGL Dekbr2 -------------------------------------------------------------------------LIANSMKEAHKQMISALNLALTASKNMILFTINLSIGTYLCLLTAAVDTTVDTALNATESIIDVANETVISFANDL-DDGLGDIS-TIANKIISG-QVNISSLRS-WH-I-SGS-INTKLESLKN-K-TLDFDDVKS-KTNSL-ISTPFEMIQKQVDE--LYIPFC--DSSKEFYDRAAKVVYKTSLILMIILIVAMLVFMIYQSWIEYRGWKHILEAATELQLRWLINYCSSSYSLPILLLGILGLLSFGFQSIILNKVSKSVSASINDSVSCNHTNSYILDYQDEINNSTLG-WVHNVTSSVNNTVTTFISEMNTKLDDIFGGT-I--MYEPIQGVVGCILTRKLQQITKAMTWVNKNSQ-VSFETIDPDIKTILQDYRK-SLRIELYISLGLIGLWLVII---- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 T-PYLTLPYILSLTWLAYPIISVLFVAFRLAISSASAVADAKANLLASCAAAEKA-ATVAASLPRYMAIGTNKQIADAVNGTMNAARATLVLSLTIVEGIINFMIDIYRSTFFCFLELVVRGGLSLLIEAVNDINNVLTGTFNTIRTGI-QNDVQSIN-SAIQSAINP-QFNLSALQN-VT-L-PDS-IQSSLTQLNS-S-LPTLDQLRD-SIKDF-VDTPFEDLKADINSQTLFVPFC--GDMDSVVDDLGRDLIKITKIGIVILVVLALLLLAAHCALEWYKWRCLQQHLEYTRLQWFFHYVFHPPVLAVFLIGFLGLLSVELQLLAVNTIATSINASMYNQSAANQINTQVNTTQTTINDGLFG-WVNGTTTTLNDTLVNFYSDVQNAVSTVFNGT-V--LESPIQEFVRCIIGTKIEALENALTFLHDNLN-IDIPRMNESVGKLVARYVD-SLKKERLMFSVFIGLWGLVVVIAI Fusgr1 T-PYLSLRSRLSQIWINRWTVLLILVLIRVMILIVDLVGDAKIKALSACTKVEDV-GSAMASMPHYLSRGVNELAASGIEKSVDAMVYMLDLVLVGVKNMIIFYINFLTATYVCLITAMVHGSLDVVADVTEGATKKFNSLIDKATSKI-ESISKELE-DGINDITDP-KVDIKELKD-FD-LKSED-FVKDVRQLDD-D-LPDFKEVQN-LTEQA-ISIPFDFVRKTLDRNAFPLAFC--SKNDNFFNNLFELIAKARTIFIAVLIILALAVIIPMAWLEIRRWRRQQQHARLIAVRWLFAYATSVPALFILSLAIAGFFSCFCQWLLLGAFADDVVENLESVSAANDANGVITGFSDDINHDILG-YVTNTTDAVNDTLTTFLETMNDGLDTVFKGT-I--LLDPIKTVLYCVIGNKIEGVQKGLTWVHDHAE-VNFPLFENDVKAVTDWLHN-KLIQDALISTGLVLLYVLVVLIGT Galma1 T-PYLQLPHLLSLTWLAYPILSLIFIAFRLQLSLSDAVASAKGDLLTSCKAAEEA-ATSAASMPRYMALATNKQYADAVNASMNAARAALVLSLTVMEAIINFIVDIYRSTFLCFLELVVRGGLAILIGAVQEINNVLEGVTSTLRSSI-QSDIASAN-SVIASAIDP-QINLDSLQN-VS-L-PAS-FTDALTSLNA-S-LPSIADIKD-KVESV-IDTPFELLKKDIEPDGLPVPFC--NDLDSVIDDIGRDFVKTAKIGAVIIILLALVLVGLNCLLTWYKWRCMKRHLQYTRMHWFFNYIFHPPALACFLIGFFGLLSVQIQLLAMTRIATSINQSMYNQSSANDLNGRVDSIQSTINDGVFG-WVNGTTTTLNDTINEFYNDIQGAVSTVFNGT-I--LESPVSEFIKCFIGSKVDAIENALTFLHDNLH-VDIPRVNESIGKLVDSYAA-SLKKERVMFAIFLALWGFVVLMGL Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Gloin1 K-PYVGLRSKLSLSWVNYTVIALMFIILRLFIAMNSIIDQVKEKANRSCDALEVA-SSTVTSLPHFMAGGFNRATIDGVNLTIKGAARMIDLLIVAMDGIIIWLIHVYTRTYQCLLEFAIRGSIGTLTASIQAIGDATNGQLNGIKTQI-DSQLSGVN-SAINKAREPDTVTLDFLNN-FQ-L-PTTDINNGLNTLNG-N-IPTMSEIES-KVSGL-ISIPFQELRGTVNETALPVPFC-AENLDSILDDISRDLIKAARIGLGIIFVVVLLMIVANALVIWYTHIRYKLHISRT-FRWFCDYILHKPALICLIIGMSGIIGIYLQLAVLNSVGNLINSQLSSTSNASDSNNVIGLLENDLNQDLLS-WVNVTTTTLNNTLNTAVDEITTFVQNTFKDVPV--LIPIVQQLVDCLILTKVEGIQAGLTFIQNNAF-IGLPRVNNSIGKIFDTYEK-NLRAELPLFYVLTSVWFIVILMGI Hisca1 T-PYLGLRSRLSQIWFNRWTILLLLILARVLVAIGSLLVSAKREALSACSSVESV-GSTMASMPHYMAQGVNELTATGVEKAINGLMSMLELTVTGVEEIFVFFVNVMTQTYLCLITLVVSGMMNAAIDVLKKATEFLDDITGKLGNAI-GDGISDFE-DAINGFGDP-KLNIKELEN-LS-L-PDG-LTDDLNKLKE-K-IPNFEDVNN-FTNNA-LRMPFELVKKLIDRSVFPVPFC--NEEGSFFNKLASLTSTAKKIFIGVLVVSAILVCIPMAYREMRAWRGMKERSSLVRARWVVAYVTSPPALFLLSLGVAGLFSCACQAMLLGQFADKVFFALNNASEAVGTNRVIDDTNDDINQKVFG-WVNQTTGSVNNTLNVFVDETSNVLNRTFGGT-I--LYEPIKDVLHCLIGLKIEGVQKALTWVSVHAK-VDFPNLANDVQRVTDSVES-GIRTEAIISAVIISIWFAVLLMAI Klula1 H-IYLKLNERLSQIWCNKYTIIILVMMVKILLFIKMLFENIMDYTMENCRNIDYYYSKYVNSSPHYMGLMGNFLIQKSMEQSVALSLKSISLLVSVSENVIDFMIDLWLGTWVCLIVSAIDGSVDVATNATESVIDLVNGTVSSVADEI-DDGLSGLT-KVVNKVLSK-KVNINGLRT-LS-I-PSS-IDDKLVKLSA-N-TPDFDTVKN-KTKQA-IAVPFDIIRNEIDPQYLEVPIC--SDNKEVFDTIRKVFNASTMTILIVFILAALSLIVYNAWAEWRQWIRLKRFRDQYRIQWLVTYLTSSTSLTLLALGLCGILMCCVQFAIITSMSTAMNDTVQQGMTSKSANLYINDTETQINRQVFG-WIQNTTDTVNGTVTDLIEDIDNAISKAFNGT-I--LYKPMDTVMQCVIGNKLEAISTALTWVHNTAQ-VNLPRVNGSANKILSQYKN-TVVIELIVSSVFLALYFFQIPVAG Lacbi2 T-PYLQLSHLLSLTWLAYPILSLIFVAFRLQLSMTSLILSVKSDILSSCKAAEHA-ATAAASMPRYMALATNEQFADAVNGSLHAARVALVVSLTAMEAIINFIIDTYRSTFFCFLELVVTGGLAVLISAVQGINTVLQSVTGSLRTSI-QSDIASAN-SVIQNAINP-QIALDALQN-VT-L-PAS-FQDALTSLNA-S-IPTVADLKG-ALESI-IDTPFELLKTDINSSILPVPFC--NDVDSVIDEIGRDFIKIAKIGVVIIILLALLLIGFNCLLTWYKWRCMKRHLEYTRLRWFLHYIFHAPALACFLIGFFGLLSVEIQLLAMNVIAASINDSMFNQSAANDINSRVDVIQSTINNGVFG-WVNSTTFTLNATINAFYTDIQKAVSTVFNGT-V--LESPANDFIKCFIGGKVDAIENALTFLHDNLQ-IDIPRVNDSIGRLVKAYTA-TLKKERVMFGLFLALWGIVVLMGV Lenti61 R-PYLQLPHLFSLTWLAYPIISLIFIVFRLQISSDSAVANVKADLLASCKAAERA-ATSTASMPRYLAIATNEQISDAVNGTLNAARATMTLALTVMEAIINFVIDIYRSTLLCFIELVVRGALSILLGAVDEINKFLTSTFSGLKTSI-QNDVSGIN-SAIQTVVNP-QISLSALDN-VT-L-PSD-FTTALQNLNN-S-LPTVADLKN-KIEDI-VDSPFELLKKDIDVSALPLPFC--DQMDSVVDDLGRDLVKMVKIGTAILIVLIFLLIAANCWLEWYKWRAMKDHFRRIKIIFFAHYVFHPPALACFLIGVFGLLSVELQLLAINLIATSINASMYNDSAAGQVNARVDAVQSTINDGMFG-WVNSTTTTLNETVNTFYTDVQNLVNTVFGNT-I--LNDPVQEFVRCFIGSKVDAIENALTFLHDNLH-VNIPRVNDTVGRIVSVYVK-SLEKERVMFAIFIGLWGIVVVMAL Malgl1 -----------------------------------------------------------------------------------------------MIRILVQVVLSSYKSLLLCVIQFVVQGVLSVLDAATHAVSHAVHDAAQFLRAIL-DTLFQAAD-GVADIMTD--QQK----------I-PTH------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------WSE-----------------------------P-----------------------AALRYVTLRAR--------------------------------------------- Mellp23 M-PYLGLRARISLAWLAYPILIIILILIQLFLTLGSVVLDAKRDLAASCAGFEGA-ASVAASIPHFMAQQTNEFIVSSAENIVHGLATVLDLSIRAIEAIILYIVDTYRSLYLCLAEFVVRGSLALLISAAEEAEKVFADAVSGLRTAIPEATIGGAE-SLLSDTIKP-NLQLTALQN-VK-V-PTG-LSDALTQLNS-S-LPTLNELRD-ALDKV-ISTPFEALRVEVDRTLLKIPFC--QDLDSFLDKVGDVISSGLKLIILLLCIVILIIFLFNVFKERFLYKRMINKVDEARLPWFLAYITWPSALLFLGFGLLGFLVIQVQLFALNLLADKINDQTRNASAAEDTNAVILKFQSDVNDHMLG-WAGTTTTTLNNTLTTFYDGLTTVVSDTFGKT-P--LKGPSLELLNCLIGSKVAGIQSALTFVHDHAH-VELPTVSPTVDRLINRYTK-ALLKQRVTYIALLACYLLVIIFGI Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 Q-PYLGLGAKLSQAFASYAVVFLFISAFQLYRTRTTVTADAKASIAQECYALEKS-FSTVAALPNLAAQGINRGLVNAVETSISQVGYGLVVVLTGLISTLELSMSLLTGTWRCFLANLADSGIPLL----------------------------------------D-------------------------------G-IRAIDELNG-AVLGL-LAVPFNGLGELINLVTIPVMFC-EEALDVAVDKLASDFGQWIYYGTMVLLAMALVVMLGKMVVIWYHHRRWMTFVGRVQYLWFIHYVAHPPAIVCLFIGLLGLMLTFGQIAFITTVFHSVQGAMQTASVSTETNSALSVVETDLNEAVFS-EIIRAAADLNNALVQVQTTLTDGVRTAFGDS-I--FAKFVGAVLRCLLFNKLESVERGLSWVRENAR-IQLPRITEDMSGMFTHYEE-ALRRELPLYYGLVSVWLIVLAMGL Mucci2 N-------EQYALAWLQISTIALFTLIGSLVYLLNYMLNASRSRLETVCDSINTL-SEQIYNAPSILLQASLHSVYTAK----DNIHRNLSTAVNVIESVVVWLISMYKSTYRCLLGLAVRSLLSLVTQIAGPIQQVA----QGVTSFL-HL--------------D------HIMG-----------WTDSLNATQH-K-VDEWFKNDDALIRSW-VDKPFNALQGQL-----PLIPC--RSDQSAINQVEHELAYFVYIAIGVLVGLVVVLTAIHLIVIRFRHHQVAQARSLFLLHQLLHFMSHPIAVYCLVVGVAGVCMTWGLAWLMANA----TAEWINAASFTSINGWLDQTELDLNNHAFG-IIKESAMTINSTLSNVVDQIHTLIQTVLGGT-L--LETPAKELTQCLLLTKIENIEQGLTWIADHSY-VRLTRID--MN---DSS----------FITEQLNICALA----- Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 T-PYLGLRARLSQLWFNRWTILLILVLIRVIILTANLLGDAKAKALSACTKVEDV-GSAMASMPYYMSKGVNVMAAGSMQKAVEAMASVLKMILTGVQAIIMFVINMYIGTFACLVAAFIHGGLHVATAVVEGATKVMNDAISSITKGI-TDDMKSFQ-SAIDKARDP-TINIRDLQG-IK-INANG-VVNGLDVLDQ-K-IPTFDEAKN-LTESA-LAIPFNLVKGKIEPTIFPTAFC--SNNSDFFESLITLVYKAKIAFLVVIIILALLAIFVMGYIEYRGFKRERERAARMDIRWAFAYATSLPALFVLSLAVAGMLSCLFQWVLLGDFAGDVVGTLKQVSNANSSNAVVANMESDINSDLFG-WVREATESVNNTLTVLDDQIDHALVAVFNGT-V--LLDTARDVVGCLIGRKIDAVQDGLTWVHDHAK-VTLPRFDDDVGKVIRSLRN-GVIQEALITLGLFLTYVIVVLIGV Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 T-PYLGLRARLSQVWINRWTILLLLILFRVLIAVGDLMASAKREALSACTSVESM-GSAMASMPYYLSKGTNELVASSVDEAVSALKSVLLLTITGVGEILWFVINMMYSTYACLITMAVRGTVGAGIELVKEATEWINKTLQSISGEI-ESTVDEYK-DELNSFLES-PINISALEN-LS-L-PSS-VNRTVEKLDSVV-LPNFKEIQN-YTKTL-FQTPFQEVKDLVDRSALPVPFC--NDNKDFFNGVTELALKARKIFIAVLFVAAILVCIPIAWQEIRRWRSMKERSQLVRVRWAIAYATSIPALFVLALALAALFSCLCQYLLLGEFADKVVDSLESASTATDANKAIMDLDTDLNHNVFG-WVNSSTQAINGTLNFFIYNTSSVLNETFKGT-L--LQEPVYELYECLIGLKAEALQKGLNWVVEHAH-ISLPTLPNDVIAVINKLEE-AVRMEAIIATVILLLWVFIALIGI Phybl2 NYPFPRLMEEYCFVWLSGGTLILLSVLMPVLQFHSVVIQGIQSDIDETCQDINNA-VFHLRDLPNTLSWHVLKSAATSV----DNLQRVLITLLSVIQSCVVWLIGVYKSTYRCLLGLAINTILSVATTLTEPIQKVATTVLDGIAQGV-HAITDPLA-ALTGTKPD------FQMSN----------WTKTMDDIRS-K-VYNWTEGPD-IIDTL-VGAPFEAIKSHI-----PLQEC--DPTKHIVQDLDDQISSIIWTAVGLIVLAMALCTVWVAIYRYLCHNYLEDRRSLKILEWWITLLSNPFTLYCLLLGTCGLLTTYALLWTLRDT----TADVLQSLSLVELNGWISQTEAMINDQAFG-FIRSVSLSLNTTLSGVVGHLTTFVQTVLGGT-I--LEEPAKGVLGCLVLVKLENVEQGLTWIVDNVH-INLTRINPN-----DLSIEAQLNKHLQFYWVLIYVWLMCLAIGF Picst3 M-PYLNFAERISQVYLNKYTLALVLVTIKVYLFQKTLVRNIPDFSD--CS---------VDELPTKVSVMIRNMVENNLNSFTYSTLALLHVAAKSILNLIWFAVEMLLGTYTCLFKAAIVGTSDFAADTSEMVVKGLNTTIVEITHDI-QLGLDGLS-SILNKVVSK-SISLGKLTN-LS-I-PSS-VLGEINKIRI-D--PDFSSVEN-STKKL-IEEPFTSLTNQWGVKFPLLQ-C--DIGSELSHNLSTSVEMAAKIVIIILAICAVLVMVPLIYDEWRKWNREERIIGN-L--WLSTYVFSNYSISFLLVGLLGLFVVFLQYIIL---TSQMTKELLNMTSLSQIDSYFQKQEDNINDKLFG-SVKLTSSKINSTLHEFMSTLNDTVNSIFSNT-P--FSGPVNTIVYCTIGRKIDKVESGLTWINDNLS-VKIPNINKKVQKTIAMYKL-NLFLEFVISISLVGVWVMQLLIG- Plicr1 K-PYLQLPHLLSLTWLAYPILSLLFVAFRLQLSVASSVASAKGDLLTSCRAAEQA-ATSAASMPRFMAAATNQQIADAVNGTMNAARATLVLSLTIMETIINFIVDIYRSTFLCFLELVVRGGLSILISAVQEITNAVQSTVSGIRTNI-QNDVASAN-SAIQSVVNP-QFNLDALQN-VT-I-PTD-FENALISLNS-S-LPSIDDLKN-AIDSI-IDTPFEAVKADIDASTLPVPFC--GDLDSVIDDLGRDILKAAKIGTLILILLVLLLLAGNCALEWYKWRCLKRHLQYTRLQWFFHYIFHAPALACFLIGFFGLLSVQLQLIAINTIATSMNASMYNQSSANDINGRVDTIQQTINEGLFG-WVNGTTTTLNSTLNTFYDDIQNSVTKVFNGT-I--LESPVQEFVRCFIGSKVDAFEEALTFLHDNLQ-INIARVNDSVGRLIAAYVN-SLKKERIMFAIFMGLWGVVVLMAL Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 T-PYLRLPHLLSLTWLAYPILSLVFVVFRLLESSAASATNAKADLLASCKAAEHA-ATAAASMPRYMAAATNQQIADAVNGTMNGARAALVLALTVMEAIINFIVDIYRSTFLCFVELVVRGGLSILISAVKELSDFIENTFNGLRTSI-QNDIETAN-SAINSTINP-QISLTALEN-VT-L-PTD-FEQSLESLNN-S-IPSFSEIKD-KIESI-IDTPFELLKKDIDASVLPVPFC--DGLDSVVDDLGRDLAKLTKIGILILALAALLLLAGHCALEWYKWRCLKQHLRYTRLQWSLHYVFHPPALACFLIGFFGLLSVELQLAAVNTIAASMSASMYNQSAADDINARVAAVQSTINDGVFG-WVNGTTTTLNDTLNAFYDDVQDAVSAVFNGT-I--LESPVQEFIRCFIGSKVEALEDALTFLHNNLV-VDIPTVNQSVGRLVNSYVA-SLKKERIMFALFLGLWGVVVLMAL Rhior3 Q-------EEYALAWLHLSTISIITILIHLSQALSRLADASKARIESACSTLDSI-ASQLFNAPHVLLVATQSAIQTTK----ENVHHALSAALTVIKTTLVWFIQLYKSIFRCLLGLPVHTLLSLLTQVAGPIQKAT----EDIASVL------------------------HFLGN----------WTQGLQGISD-R-LDHWVQQEDDWVQQM-VSMPLDAIQIKL----APVLVC--DTAADAVDRLYAQATSSVWWMMGLLVLCLALSIALQAYSVKRKHQRIQTARDSLLRCRFLGVMSRPVAIDCLLVGLTGIVLLHAFVYVLNHT----TSHWATEAGLEEMNDWVHRTEVDLNEHLFD-TIKSTALGMNHTLSSVMGEVQEAIGSILGGT-L--LEQPAQGLVQCLVTNKVENIENGLTWIASHAY-IHLTKMD--VD---DGSSSASLRTLLGFYYTLLLFWLLTIVIAT Rhoto1 R-PFLGPRAHISLSWLSQEFLALILLLIALAFLLASLTRDAKASLLSACTGVEGA-ASVAVSLPHYMADGVNELNVRTVNAVTHGLGEVLDLMLQALEAIVLFIIDTYRSLYLCLLDLAVHGSIAVLVKGIEEAQGFVTDAISGVRTAI-QASIGGIE-TALNKTVDP-SLDLSALEN-VT-L-PDT-LVNALTSLNS-S-IPTLSEFRS-TLDNL-ISKPIESLRANIDVELLPIPLC--TNLDTWIDDVGSDLGKFVKVAIGLVVLVMALFIIANALWEKWRYRVFLGGVEAARLIWFLSYIAHPPAWAFLALGLVGLIVVQIQLAILSSVMGALNEKMRDASEANGTNKVILGLQDDVNNNLFG-WVNDTTTSLNSTMNGFYTEITDTITEIFNGT-V--LEDPALNLIYCLLGSKVDSISTALTWLHDHAH-LSLPTVSPSAEKMVNAYER-NLEQQRLGFIVAIGVWVLVVLMGL Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 K-CYLQLGDRLSQIWLNKYTLVLLLAMLKLLFFSKSIIEVSETYILSNCYSIDSLYSKMTDNTPHYLGIMGNYLIEKGMEETVKATLETLSLIVYASEGLVNFAIDLYLGTYACLIVSAVDGTVDVATNITEKLISLVNDTVSSVANEL-DTGLNDIS-KIINKVIKK-SVNISALHN-LY-I-PSS-INDKLEELSA-K-TPDFAQVKN-TTKNL-ISVPFNEVRKNIDTSVLYVPIC--SSNQAFYSILGHVLKIATVVCITVLICFAVGAMAPVAWNEIKLWRRLCGMRDHYMIEWVVAYMTSERALCVLGIGLLGILVCICQFVMINLLKSSTAVDIENQMSSVQTNKYINTTETNINQEVFG-WINTTTLSVNNTVATMISDIDTTLADVFNGT-L--LYNPMKTVVGCAIENKLYTIEKAMTWIHDKAQ-LHIPRINGTLLKILRAYHR-ITLGELTVALVILAVWLVQLPIAL Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 K-PYLELPHLLSLTWLAYPILSLLFVAFRLAISSSSMVDSAKANMIASCKAAQNA-ATSSASLPRYMAMGSNELFADSVNATMNAARATMVLALTIMEAIINFIIDIYRSTLLCFVELIIRGGISLLISAADEVKEFVENIADGIADTI-QSAINGAN-SAFQTAIDP-QIDLSSLTN-LN-L-PTT-FQDALTSLNN-T-VPTFDEIKD-AIEEV-INTPFELLKADINSSLMKLPFC--DDLDSVVDDLGQDIIKATKIGIVIIIVIALCLVGLNCFLVWYKWRSQIQHLDSTRLTWFLHYIFHAPALACFLIGFVGLLSVQIQLIALNNIATQINGSMYNQSAAADVNAQIAEMQQHIDGGVFG-WLNTTTVTLNDTLVKFYDTVEDAIEGVFNNT-P--LEQPVQEFVFCLLGSKIVAIENALTFLHDNIQ-VELPTLNETVDKLVRAYTE-SLKKERIMFAIFVGLWGVVVLMGL Schpo1 S-SYLSLAARLSQCWISPWSLCCLYILMQFFLFTKDLIGDFVNDEQATCNYIQEK-VDILLDSPSLIANAAVRVAKDGIQSTVKIILSGISDSLIAAENVFIFFIEFSYGTYLCLIQLAIDGILDAVADVGEEIGTAVNDTLHAIADEI-EDTVSSLN-EVFQSAEDP-NVSIQSLRN-FT-L-SSS-YDTEFEKLKA---GVNFDSAIN-ATKAA-ISKPFSSARNLIDTSMVSSPVC--STDDAISSFILSSIYKIRKVVIISLLIIIAGLFLISSIYEIWKWCRIRHKAFLLDLRWFITYIFHPPAAMILFISCTSFISGILQLVLLQNSFHKVESALANVSVANSTNQIILKNQENINNNMFG-SIHNTTLSLNSTLNTFMNELNSSMTSAFGDT-F--LASTVQNVMNCLLYRKIENFEEVLTWVYNKSH-IELPLLPTDFSGIFDRVEK-SVISELNFSFLFFLLWLLICAFGL Sorma T-PYLGLRARLSQLWFNRWTILLLLVLIRVIILTGSLIGDAKVKALSGCTKVEDV-GSAMASMPHYMSKGVNKMAAASMQGALDAMQAVLKAILTGVQAIIMFVLNMYIGTFVCLVAALVHGALHVATKVVEGATDVINKGIEAVTKGL-SDDMKGFQ-DAVNSAIGP-KIDIKDLQG-IK-IDAKS-AIGGLDALDK-K-IPTFDQAKN-LAESA-LAIPFNLVKEKIDEHMFPTAFC--SNNSDFFESLITIVHKAKMAFFIVIIILAVLAMVVMGYLEYRDYKREKERAEVMDVRWAVAYATSLPALFVLSLAIAGFFACFCQWVLLGDFAGDVVGTLKQVSTANDSNAIIKNMESNMNSDVFG-WLQEATESVNNTLITVENEIDKTLKTVFKDT-V--FLDIARDIVGCVIGRKIDSLQDGLTWLHDHAR-VTLPRFDEDVGKVIRSLRN-GIIQEALISLGLLLMYIIVVLVGV Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 G-PYVGLSAKLSRAFVTHIVFALVVVLYTLLILAQTVGEETKQRLRSGCNGMEVA-ATAMASVPHYAAAGFNQATVDSINAITSSTAKMLSGAVAMLNELVLMVLQSYTNLLFCILDAFVGLAVNTVAMYAEQITDFLNTQLAVISNAL-EKSLDVLN-GQLQNFVDP--VRVSNKLN-FQ-I-PDD-FVNTLKNLSN-E-VPSFEDLGE-QLATL-ISKPFGLLEGLIDAKLVPIPFC-DDAMDGWIDELVHALNLALLLGAGLVAAIAFFSILANMVTVVYDHWQFEKSVRLYAFHWFVDYVSHKPSLLCVCAGLLGLGMVLLQMWMIDKLVRTVVAEVYGVAQVDATNNQIDLVETTTNRVLFG-WIGNIIDAINNTMSTFEQGFNNALNSAFGSVPP--LKTALVAFANCVVGSKIRTLEAVFEALTTKSH-LTLPRIHLNVEAFLESYRN-SLRQQILPFLAIFGFGSLVFFMGL Sporo1 H-PYLGPRARLSLSWLSQHFLALLLVLVALGFFLSSIVKDGKATLTAACSGVEGA-ANVAVSLPHYMADGVNELNSKTISAVANGAGTVLDLTLQALEAIIIFMIDTYRSLFLCLLDLVVHGSLTLLVHAIEEAQQFVTEAISKVRTGI-QGAIEGVN-TGLEKTIGP-TIDLSALAN-VT-I-PST-VVDALTDLNS-S-IPTLDEFRA-TMNSL-ISTPIEALRTNIEVEMLPVPIC--TDLDSWIDDVGSDLGKFVKIAIGLVVLLMVLFILACAVWERYSYRNFIGGVMSARLIWFFSYIAHPSAWAFLALGLVGLLVVQIQLWALNSVVSSLNRKMNESSFATRSNQMILSVENGINDDLFG-WVNGTTEALNSTINGFYNGLTSEISDVFHGT-V--LEDPVLNLVYCLVGSKVDAISTALTWMHSHAH-ISLPTVSPTVDKMLRAYER-FLEQQRLGFCIAILIWMLVVVMGL Stehi1 T-PYLQLPHLLSLTWLAYPILSLIFIVFRLQISSDSAIANAKDDLLASCQAAQTA-GASVVSMPRYMAIATNEQISDAVNGTMNAARAALILSLTIMETIINFLVDIYRSTFLCFVELIVRGGLSVLISAVQDISDAITSTLNDLRTTI-QNDVSSVN-SAIQTAIDP-QFSLDALSN-VT-I-PTD-FEDTLISLNN-S-LPTVSDIKN-AINGL-LDTPFEAVKADINSSALPVPFC--DDMDSVVDDLGHDILQIAKIGLILVIVCIFLLLAGNCLLEWYKWRTLKQHLQYTRLRWLLQYVFHPPALACFLIGFFGILSVEIQLIAINTVATSVNQSMYNQSAANDINSRVDAIQTSINDGLFG-WVNGTTSTLNDSLVTFYSDVQNFVTLIFNGT-I--LEQPAQEFVQCLIGSKVDALEEALTFLHDNLN-INIAKVNESVGKLVNAYVE-SLKKERIMFAVFLGLWGLVVLMGL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 T-PFLGLSPRLILATLSPALLPLILTIAHLIQTRSSTAASLKSSILSACDGLAQG-AASIQMLPRYLAMQTNDEVVRATQASILAIGAGLIDCVTIIETVVGFIVDTYRSMLLCTIQLAIQGTLEVVIGAVQVISDNITSTMNSVRTGI-QNDIASAN-SAIQTAVTP-EFSLSALEN-VT-I-PTS-FEDSLIKLNS-S-IPSLDTLRD-KMTAL-LDTPFEALKTSINSSILPVPLC--NGLDSLIDDTANALHKLSSVAIGLMFLLLFLAWAALCVWEWHRWKVMKDTVDAVQLRWFASYLAHPTNLTLLFISLLGLIALSFQLLALNALITKLNAAAQNSSLANQFNTAVNVYEARINEELFGSWINTTAVTLNSTLVEFYNEIESILNSTFGGT-I--LYNPINTFVYCILGSKITNLEQGLTWVSQHAQ-VVLPTLPTNVGSLIDHFES-ALRVERNFYAILLGVYVALFLIGL Trire2 T-PYLSLRSRLSQVWINRWTVLIILVLVRTIILTSQLLVTAEAQALSACTKVEDV-GSAMASMPHYLSSGVNELVAMGVEKTVHGMVEVLDLVISGVEGIIIFYINFLAATYTCLITAMIHGTLDVIGNVTEDATKAYNHVVNGTVNEI-EKIANALQ-RGIGNLTSP-KVNIEELRD-FQ-INTTE-FVGGVQKLND-D-IPTFEEVQN-MTESV-IAFPFNKLREALNRSTFPLAFC--SDNDNFFDGLFKLVAKARTVFIVIFVLAALGAMVPMAWLEIRRWRRQKEHAKLVSVRWCIAYATTPAALFVLSLALSGFFACICQAILLGAFADHVVDSLQNVSDARDANDVIKGLNDDINGDLLD-YVSNATGAVNDTINTFMDKMEGGLNAALNGT-F--LLGPVKSILHCVIGLKIESVQKGLTWVHDHAH-VELPLFPNDVGHVTGWLHK-NLVQEALISTGIFLVYVIVVLIGV Umbra1 SAPI-NLHAEYSLAWCNTAVILLLSLVFTIQVFGSTVAASAQSEIATMCEMVDTT-AKSLTTAPSALLYMLNNEAETSVLFALNSTRQGLLNAIDGVDALLTWFVDTYKSTYVCLLTLAVDSSIDVVSDVANTFETTVQSILSGGTVGV-NNVVNSVEHTVFGN--D-----PNITSN----------WTSSLNALDA-K-IHNWTL--DSVVSSV-ISEPLQDLKTTVSVQIIPVIPC--NATVQDIQDVANKLLGVSGTLTYILIALMLVMTLVNMGYRHVVNNWRNSMARSFVLTWLMDYVSEPAALFALAYGLSGLVFTTLAINLINNSFHNISATLITVANVTDTNLAIDTLEYSVNHDALG-WINTTTAVLNSTLNQVSSDITGVVTDIFGGT-V--LENAAQGLINCLVLNKIQSIETGFTWLNNVSH-IQLPRVSETLDRMLDQCIS-SLQEKLPFYWVLVSMWLFILFIGC Ustma22 Q-PWLGLQARLFLAPISIPLISLLFVAARMLSSSNEAISSAKGKLLSACSAAEGT-ASLAASFPHFLAASTNVQLALSVTATVHSAARVFDLSMTAIQKILTYIVNSYKSLFMCFMELLVRGALAVLITAVEFISQAITAATLGIRSAI-QESITGVN-TLLATAVGP-HIALTSLEN-IT-L-PHE-IQDGLVKLNA-T-LPTLQQLKQ-SMDAL-IETPFEEMKREVNHSVFPVPFC--DRIDSPLDELGNALKNVARWGLVALLLIAIVVMLIGVAWEWWKWQKEVKAVERTRCAWLLSFLMHPASLACLFTGVLGLISVLMQAILVSDIVNLVHDHTRNASVSTSANTVILQVEAELNDHVFR-WVDTTTSTMNSTLNQFVDGLTETLTSTFGGT-P--FNAPLQTFVQCILGQKVQGIEKALTWIHENAY-VNFSVVPADVGHVISRYME-HLHQEKILFTALIGVYAIILLIGL Walse1 R-PYLGIKSRSAITLLAPFIIGVIFAIVTIASFRTTIAGSTIASANSICRHVQAT-AEDAFNMPLQAQRKLGQQVQDSITDIIAGLESVLLLLIKAIPIIVMFFIDFYRSLLLCFIQLIVQAALA----AVTELVSLASSAIEDVAHTI-GDAVSGAF-NVANDAID--PINLDALNS-FQ-M-PDS-VQNTLNEIND-R-LPDLEDLRN-YLNGIDVQGKFDSYKTSA--NALATSFC--SDLDSVVTDLASTIKKIGLVIIITLSILALLYIIFLVYLERSRHYQTKQFIEDYAIRWFALIMMHPYIVTLFCMGLIGFVSTGAQLVIITQLEQALAAST---SGSNKTNNAIDIVETTINDDIFG-WVDEGVVPINDTLTAFEDGLNNAIETAFNGT-F--IEDAIANYVQCVIGSKIDTLESGLTWIHDNAH-VNLFRVPED--------KE-SLTRSKVR---------------- Zygro1 T-SYLQLRDRLSQVWLNKYTLVLFLAMVKLIFFSKSIIKQSENYILSHCNVIDSIYAETVGSTPHYMAVMGNFLIREAMIQSVRASLMTLTLLVYASEGLLNFVIDLYLGTYACLIISAVDGSVDVATNATEKLLGAVNHSISAVANDI-DDGLDDIS-KVVNKLVSH-KINVDSLRN-LH-I-PSS-INNKLQELSD-K-TPDFAQAKN-LSKRL-VSVPFEEVIKEINSSLLYIPIC--KASEKFYDGISHALTVTTVICTVLLVIGALCATIPVAYSEFKLWGRLLEMRTQYTIRWAVAYVTSERALCVLGIGLLGLAVTILQLILVDLKDTQMGKILEQDMATHSANLYINNTQNNVNEHVFG-WVDKTTVAVNHTVNEVINEIDHTLVGAFNGT-L--LQKPMKAVVGCVIENKLYAIEKAMTWIHDKAR-LDLPDINLSIKLILDGFHK-TAIYQLLVALSLLGIWFLQIPIAL [Cluster3392.fasta_al_trimmed; alignment length = 85] Allma1 ------------------------------------------------------------------------------------- Ashgo11 MGASCKDQRKAVAICLQRSPCVMIERNTPKKCLEDQMPDLCIAQMRSFLECKRGMVDMTKRFRGNTGRYDQQYAEMQKLEELDES Aspfu1 MPSSCRELRDALAQCLQESDCIMVQRHTPRECLSTELPMKCQQLRKGFSECKRGLIDMRKRFRGNGGK-SQSH----QMDPEKTR Aurde31 --MSCEPILNALKQCLLLSDCVQKDGRLPSDCLKNELPEECQLLRLSMFECKRSMLDMRKRFRGN------------HRAASS-- Batde5 -MPSCDRFFEDLAECLMASDCVVKYGKRPQECVEAYTPSECMLKHQAYQECKVHLMNPRRRFRTP----DSNVQQY--------- Botbo1 SDGICEPLLASLKECLLRTDCVLKQNFPPSVCLKEELPLECQHLRQALFDCKRSKLDMRKRFRGY--------PDKPNVGGA--- Botci1 ------------------------------------MPTKCQQLKTGYGECKRGLVDMRKRFRGNGG--GERNKDWRQLENERYR Caeel TGVSCDRLRQALKKCIKNSHCVQVQARSAKECIDASVPDKCFAVLQNFTDCKRSLVDMRSRFRGR------------DL------ Canalb1 MGASCKDQRKALAICLQRSPCVLLDRHTPKECLSDDLPELCKAQFRAFMECKNGMFDMRKRMRGNTGKYDETFEEMRKLDVLNRN Cangl MGASCKDQKRAVAICLQRSPCVMIERHKPQECLDNDLPELCIAQMKAFLDCKRGMVDMTKRFRGNTGKYDQQYEEMNKLNTLNSS Capow ------------------------------------------------------------------------------------- Catan2 MSSSCKKLRQEMIDCILASDCIEKHNKSFTECLQPLVGYECRQLQRAFFECKREMLDMRYRFRGN-------------------- Cioin ------------------------------------------------------------------------------------- CocheC53 MPQSCKDIRAALAFCLQNSDCIMVERHSPGDCLRPTLPTQCQQLQKGYAECKKGMIDMRKRFRGNTGAFGQGRPDNKGLER---- Coere1 MPS-CSGIREEYIQCLLRSECVFINRNSVSECGRNTVPSQCHLLRQSLFDCKRGLLDMRKRMRG--------------------- Conco1 MPS-CDEIRTELIECVQKSPCMTEHRYTMQQCMEKLITEECMAIKKSFGDCKRSLLNMRYRFRGV-------------------- Conpu1 MSSSCEALLDALKQCLLESDCVRKDGHLPSECLRQSLPEKCLNLRKATYDCKRNMLDMTKRFRGN-------------------- Copci ------------------------------------------------------------------------------------- Croqu1 NQGRCSDIKQDLVNCIIKSDCVLQ--RTPKDCLQNELPEECLHLRYAFFDCKRGLLDMRKRFRGL-------------------- CryneH991 PQPACQLAKEELVACLLRTDCVLKSGKTPQECLQKELPLQCQHLITRFADCKKGMR----------------------------- Crypa2 MPSSCKEIRAALAQCLQESECVMVQRHTAAECLRSTLPTKCQQLKKGFGECRRGMIDMRKRFRGNSEETGEGYRDWREVENEKYR Debha1 MGASCKDQKKALAICLQRSPCVLIERNTPKKCLSDDLPELCIANFRAFMECRNGMFDMRKRMKGNTGKYDDTYEEMKKLEVLNRN Dekbr2 MVASCKDQLKQVAICLQRSPCVMIERHKPKDCITKDVPDLCKAQLKTFLECKRGIMDMSKRIKGNTGKYDEEYKEMDKLKTLDSH Dicdi ------------------------------------------------------------------------------------- Dmel DETACAGVRADLKMCLLESDCCKM--KTPRQCLQDNVPAECQVLRNTFYECKRSLLDNRQRFRGR-----KGY------------ Enthi ------------------------------------------------------------------------------------- Falba MGSSCQALRQRLFECIQKSECFANNGGQGKKCLDRGVPENCRTLQNAYANCRREMIDMRSRFRGP-------------------- Fomme1 ------------------------------------------------------------------------------------- Fusgr1 MPSSCKELREALAQCLQESECVMVERNSAADCLRETLPLKCRQLKKGFGECKRGMVDMRKRFRGNAEE-GQGYQDWREVENEKWK Galma1 MSSSCQSLIAALKDCLKYSDCVLKDGHKPSECLKHELPEECQSLRKATFECKRGMLDMRKRFRGN--------------PV---- Ganpr1 MPSSCKDLRQDLLTCLAASPCITVLHKTPTQCLRESVPDDCFRLYRSFVDCKRGLWDMRKRFRGN--------DLLKDLGDDGKK Gloin1 MPS-CKELRQELVNCMLKSDCVLIKRHTVKECLQPDVPKECQSIRKSLFECRRGLLDMRTRFRGN-------------------- Hisca1 MPSSCQDIRLALAQCLQQSDCIMVQGKTPHECLQPNLPVKCQQLRKGLSDCKRGMVDMRKRFRGNPTT-GEVI----QMDPEKTR Klula1 MGASCNDQRKAVAICLQRSPCVLIERNTPKQCIEDDLPELCMAQMKAFLDCKRGIVDMTKRFRGNTGKYDEQYEEYEKLKLLDSA Lacbi2 MASSCQNLLSALKDCLIHSDCVVKQGNLPSDCLKNELPEECQSLRKATFECKRGMLDMRKRFRGN-------------------- Lenti61 MSSSCSHLLSALKDCLLHSDCVLKQGNLPSECLREELPESCKALRQATFECKRGMLDMRKRFRGN-------------APASA-- Malgl1 ------------------------------------------------------------------------------------- Mellp23 --GRCAGIRQDLANCILKSDCVLQ--RTPKDCLQNELPEECLHLRYAFFDCKRGLLDMRKRFRGL-------------------- Mnele ------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------- Morel2 MPSSCKEIRIELAECILKSDCMLKDGLSAKECLHSRIPVECTAIKRSFFECKRGMLDMRNRFRGN-------------------- Mucci2 MPSNCQEIRQELIECMLKSDCVLKKRNTVKECFKEDVPDECLSIKKSFAECKRGMIDPRMRMRGN-------------------- Mydma PAQACNALRKELVNCLHMSDCMKKDGKTMGECMKKGVSTECRATIYSFYECRRSMLDMRTRFRGR-------------------- Neucr2 MPSSCKEIRAALAQCLQESECVMVHRNSAADCLRPTLPTQCQQFKRAFGDCRRGMIDMRKRFRGNTEQSGEGYPDWRELENQKFR Orpsp11 ------------------------------------------------------------------------------------- Pench1 MPSSCNDIREALAQCLQESDCIMVQRHTPRECLSSELPTKCQQLRKGFSECKRGMIDMRKRFRGNGKS-GNSS----QMDPEKTR Phybl2 MPSSCKEIRQELIDCMLKSNCVLVKRNTVAECFKKEVPEECQSIRKSYAECRRGMIDPRMRFRGN-------------------- Picst3 MGASCKDQKKALAICLQRSPCVLIERNTPKDCLTDELPELCVANFKAFMDCKNGMFDMRKRMKGNTGKYDEIYDEMKKLEVLNRN Plicr1 ----CQALLDALKDCLLNSDCVVKQGHLPSECLKEELPEQCRSLRKANYDCKRGMLDMRKRFRGN-------------------- Polpo VGHPCQQIKDAIVKCIQQSECMKK--KTFHQCMKDNLDQDCKDLLYTYFKCKVDMFDPRNRFRGN--------NSNNDNNNNNNN Pucgr2 RGGPCQQIKADLTACILRSDCVLK--RTPKECLQSELPTECAHLRYAFFDCKRGLLDMRKRFRGL------------SNS----- Punst1 ------------------------------------------------------------------------------------- Rhior3 ------------------------------------------------------------------------------------- Rhoto1 --MSCKGIRQALADCILRSDCVLRSDRSPQECLKEELPEECQLLRKSFFECKRGMLDMRKRFRGN------------DAKN---- Rozal11 ------------------------------------------------------------------------------------- Sacce1 MVASCKDQKKAVAICLQRSPCVMIERHNPQECLDNDLPELCIAQMKAFLDCKRGIVDMTKRFTGNTGKYDQQYEEMEKLKLLNSQ Salro ------------------------------------------------------------------------------------- Schco3 ------------------------------------------------------------------------------------- Schpo1 MGRSCKVIREDLANCLLHSDCMFVKKKSARECLKNELPEECKNLIEAYGECKRQMLDMTKRYR--TDQ----------------- Sorma MPSSCKEIRAALAQCLQESECVMVHRNSAADCLRPTLPTQCQQFKRAFGDCRRGMVDMRKRFRGNTEQSGEGYPDWRDLENQKYR Sphar ------------------------------------------------------------------------------------- Spipu1 ------------------------------------------------------------------------------------- Sporo1 ------------------------------------------------------------------------------------- Stehi1 MSNYCEPLVQALKDCLLHSDCVLKQNKLPSDCLKNELPEQCRQLRQATFECKRGMLDMRKRFRGN------------DAPIS--- Tapde11 ------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------- Treme1 TKEACQGLREELVSCVLRSDCVLKIGKTPGECIKELLPAQCQHLITSFTDCKKGMLDMRRRFRGN----GDGL------------ Trire2 MPNSCQELRDALAQCLQESDCVMVHRNKASDCLRETLPTKCQQLKKGYGECKRGLVDMRKRFRGNSEQ-GKGYQDWREVENEKYR Umbra1 MPSSCKEIRQELVDCMLKSDCVVKNGNSVKECFKEDVPKECHSILKSFYECRRGMLDPRMRFRGN-------------------- Ustma22 MVGSCQHIRTDLTDCVLKTDCYLKQGNSAQECITSELPVECQHLYKSFVECRRGMLDMRKRFRGN------------QVDPTSAN Walse1 ------------------------------------------------------------------------------------- Zygro1 MGASCKDQHKAVAVCLQRSPCVMIERHTPQECFEDELPLLCISQMKAFLDCKRGMVDMTKRIRGNTGRYDQQYEELKKLELLDNN [Cluster3393.fasta_al_trimmed; alignment length = 262] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ENRFHVWEQSPSPDLRERAARIRALARCPVIRYSCERSGIPTHHSREAWLRKVNVYEHDLRSGRPFAEFD-FPDRMVNMLNWDLFLYTRQFYSMDTDFQLAAVTKMLSYPITIGSLLHQFSPYALEITLEGLKSLAALRYTLYPPMRIFILGARAEAQLPGHVWKQ-LQYLFPMEIHFIGPEPYDPYNDVFFCFHPGFATVPALLETKCAIFVTGFHRDDMFGDFEALLMHPTKNIFGSTKWELNDMNPHNMYIAGFRGKRY Aspfu1 NNLFHPFSKSPAPAIRQRAAFIKQNAFCPHSHFECPDCGVPIYCSEEHWIRQINKDDHDLHSGRFFPEFT-YPNFVINMTNWDTFLYTREFDAINHDRSMRQVTRMLTYPLTIGSVLHELSPYSIRLTTEGLKSVSALRYTLHPPVRVFILGARAESSLPRDVWLQ-LSYIFPIHLIFIGPEPFDPYLDCFVLFHPGLGTLPPLLETKVPIITTGYTQWDMERDINWVLLEPGENIFRSLRWDLNDLDPHNWGLWAFRGKRY Aurde31 DDLFYPLSQSPFKDLQQRARAIGEIAPCPVVRHACPDCGWPSHCTEDHWLREANEDEHDLRSGRHFHEFD-MPEQAISLMNWDVFWYTRGFASFDRERSRRIASKVLTYPMSVAGVLHQNSALNLRLTPEGLRSMTALRTNLHVKVRIFILGARGESFLPPGIWQQ-MAFLFPFHVYFIGPQPFDPYTDVFFNFSPGFGVVPKLLETKCMLFLTGFSPADIERDVRSLILTPGENPFGSEKWEVNDFDPRNWGIWGIRGKRR Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 DNLFHPLSQSPISSLQKRAEEVKSLAPCPVQQFECPDCGWPTHCTEAHWLKEVNEDEHDLRSGRTMAEFQ-MPEEAVSFANWDVFWYTRGFASMDTERSRRHASKLLTYPITVASLLHENSGFTIRVTPEGLRSFAALRMALHQPMRLFILGARAESSLPPHVWEQ-LSHLFPFHLYMIGPQPHDPYTDAFFAFCPGFGVLPLLLETKCPVFVTGFSPTDVERDVRSLVVTPGENPFGSEKWEVADFDPRNWGVWGIRGKRR Botci1 NNLFHSFSNSPSPEIRRRAAFMKQNAYCPHVNFECPDCGIPVSCSEEHWLREINEDDHDLRSGRFFPEFE-YPEAMVNMTNWDTLLFSREFKAINDERSLRQATRLLTYPLTIGSVLHELSPYNIKLTVEGLKSLSALRYNLHPPVRIFILGARAESSLPREVWVQ-LAHLFPFHLIFIGPEPYDPYFDCFMLFHPGLGTIPQLLETKVPILVTGYTQYDMDRDIDWVLMEPGENRFRSLRWDLNDMDPQNWGVWAFRGKRY Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ERPLYTWDESPYEDIRERAAMIRAQALCPVVNFVCPYSGIPTHHSKEAWLKKVNLYEHDLRSGRKFAEFA-FPDFMVNISDWDSFFYTRDFPPMNDEFNLAAATKVLTYPITIASILHKFSPLQLELTLEGAKSLGALRYTLYPPMRIFLIGPRMEGMLPGYIWKQ-FGYLFPFEIHLIGPEPFDPYLDIFFCFHPNFQSLKGLLESKCPVFISGYHEQELTKDIEWLILNDTPNKFACTKYDIRVTDPTNSRLFGFRGKRY Cangl QNRFHPWDQSPAVDLRERAARIKTLAKCPVIQYTCPISGIPTHHSREAWLKKVNIYEHDLRSGRPFPEFD-FPDRTVNLTNWDLFLYTRSFYSMDTEFQLAAVTKMLSYPITIGSVLHQFSPYSLNITLEGLKSLAALRYTLYPPMRIFILGARAEAQLPGHVWKQ-LQFLFPFEIHFIGPEPYDPYQDVFFMFHPGLATVKGLLDTKCAIFTTGFNKKDMADDIQILLMNPVKNVFGSTKWELDDSDPHNMYIAGFRGKRY Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ENLFNSFSNSPIPQIRKRAAFMRQHAYCPHVDFECPDCGIPVYCCEEHWLRQINEDDHDLRSGRFFREFQ-FAEILVNMTSWDTYLYTRDFDALNEDREMRQATKLLTYPMTIASILNELSPYNIRMTPEGLKSFSALRHTLHPSVRLFILGARAESSLPRETWMQ-LAYLFHFSLNFIGPEPYDPYFDCFVVFHPGFGTLPLLLETKVPIIATGYSPWDMQQDVEFLLLEPGENLFRSLRWDLNDLDPHNWGVYSFRGKRY Coere1 NNLFHRLTKSPIKEMREKSLLIQDHGSCATPTFECPNCGYPTHCSEEHWLREANEDEHDLRSGRTLREFE-FPEVVVNLSSWDSFLYTRSFTNITSDRAMRHVSKVLTYPVTIGAVLHQYSPFTLGLTPEGLKSMTALRTTIKEPLRVFVLGARAEAMLPPHLYLQ-LAYLLPIHVCFIGPEPFDPFTDVFFMFSPGIGTVEKLLETKCAVFATGFHEQDMHTDIRVLLLKPQKNPFGSLKRDFGIRNLRNWGIYGFRGKRY Conco1 DNLFHPWSKSPFQDLVDRDKMIKDYGNCPVLTYECPDCGFTTHCSEAHYLKEINEDEHDLRSQRAFPEFQ-FPDAVVNFTNWDTFFITRNFNNIEDDRAMRHVTKPLSYPLTIASVLHQYSPYLLELTYEGVKSLSAIKYTIESQIRIFVLGARAESQLPPQIYQQ-INYLFPFHIHFIGPEPFDPYRDVFFLFSPGIGTIDLLLETKCPVIITSYNQQDQDADVRTLLMPPQLNKFRSMKLDYNLEDLTNHGIMGIRGKRY Conpu1 DDLFHPFSKSPFPALKGRGEAIQSLASCPVVAFECPDCGFPTHCSEEHWLREVNEDEHDLRSGREMHEFK-LPEEAVSFSNWDVFWYTRGFPSMDTERARRHASKLLTYPLTIGSVLHQNSSLTLNVTSEGSRSLAALRSTLHVQIRIFCLGARAESSLPPNAWEQ-LTMLFPFHLFFIGPQTFDPYCDVFFLFSPGFGVIPALLQTRCPIFMTGFSPADLERDVRSILVTPGQNPFGSEKWEAADFDPRNWGVWGIRGKGR Copci DNLFHPFSKSPFPAIQARGEAIKKLAPCPVVSFECPDCGWPTHCSEEHWLREANEDEHDLRSGRRLREFE-LPEEAISFANWDIFWYTRNFPSMDTERSRRHASKLLTYPITIGGALHQHSNLTLSLTPEGSRSLAALRSVLHPQVRIFILGARAESSLPPHVWEQ-LTMLFPFHLFFIGPQTLDPYSDVFFFFSPGFGVLPMLLATKCTLFVTGFSPTDVERDVRSLVVTPGPNAFGSEKWEIADFDPRNWGIWAIRGKSR Croqu1 DDLFHPLSSSPIPAMRQKAERIRAAAWCPVVSYDCPECGYPTHSSQEAWLRESNEDEHDLRSRRPMNEFD-FPEEAITLANWDLFLYTRGFRSIDDDRSRRHVSKLLTYPISIGAVLHEFSPYSTRLTTEGYRSLTALRQSLHPPIRVFVLGARAESSLPPTVWAQ-LPFLFPFQIFFIGPEPFDPYNDVFFAFSPGFGDMKMILETKCALFVGGFSPADVERDVEAVLLHPGENVFASQKWEVAEFDPRNYAIWGIRGKRY CryneH991 DDLFHPLSGSPFPALREKADRIKSVSLCPTPAYDCPDCGWPTHKNQERWLREVNEDEHDLRSGRPMVEFENMPESAVNFASWDTLFFTRGFPSIDSDRSVRHVSKILTYPMTIAGILHQNGPFTSGVTRQGRRSMAALHSVLHLPFRLFLLGARAESTLPPHLWAQ-LCYLFPFQIYFIGPEPFDPYTDVFFAFSPGFGPLQLILETKCPFFFTAFSPLDLQRDVSALVLTPGVNPFGSLKWEIAEWDVRNWGTWGIRGKKY Crypa2 DDLFHSYTNSPIPEMRQRAAFMRQHAYCPCVDFECPDCGVPVYCSKEHWLRQINEDDHDLRSGRFFPEFE-YAEAMVNMTNWDTFLYTRSFQAINSDRSMRQATRILTYPVTVGSILHELSPYSLRLTPEGLKSFSALRYTLHPPVRLFILGARAESSLPRDAWVQ-LAHLFPFHLIFIGPEPYDPYFDCFVLFHPGLGTVPMLLETKAPIVVTGYTQYDMERDIEWVLLKPGENIFRSLRWDLNDMDPQNWGTWAFRGKRY Debha1 ETPVYNWDESPYEDIRTRAAFIRTRALCPVVNFVCPYSGIPTHYSEEAWLRKVNLYEHDLRSGRKFDEFV-FPEFTMNMSSWDSFFYTRDFNPMNTEFNLAAASKVLTYPITIGSVLHKLAPYSMQITLEGLRSLSALHYTLYPPMRIFILGAKMEAMLPGYVWKQ-FGYLFPFEIHFIGPEPFDPYLDVFFLFHPGFRSLKGLLESKCAVYVTGYHAEDAARESEWLLMNLTENVFGSTKLDLVDSNPTNKEMFAFRGKRY Dekbr2 ENRFHPWDKSPCPDLRMRAATIKAKAKCPVINYTCPLSGIPTHHSKEAWLKKVNVYEHDLRSGRPFPEFD-FPDMTVNFQNWDTYLYTRHFFSMDTEFQMAVVTKMLTFPVTIASILNQFSPYFLQLHMEGLKLLAALRYTLYPPIRIFLLNARSESLLPPHVWKE-LSYLFPFELHFVGPQPYDPYQDIFFCFHPRYAALPGLLESKCAVFSTGYHKQNIDRDFNWVLLDRTKNVYGSTKWELNDLNPQNQWLFGFRGKRY Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba NNKLKGFTQAYLEN-----------GGCGT----CP------HVDREALLRSFILDSSDLAAGKLNREFT-FP----AFDDWEAFLTSRGFYNAHLTQTQRVLSRSLTFPATVAHLFSPNRTFECS---LGDDALAELSSRASGSVNICFVGARAEATLPNEAWSQ-LMYLYPWNLMFVGP-LNDTIPDVYILFNSGVGSIERLLETTQPLVFTSLGLEDCENDIAAVLVQPQLNSFRALLCDANPYNPMNWSLFAVSGR-- Fomme1 DNLFHPFSKSPFPTIQQRGEAIKNLAPCPVVNFECPDCGWPTHCSEEHWLREVNEDEHDLRSGRRMTEFE-LPDETVSFANWDVFWYTRGFPSMDTERMRRHASKLLTYPMTIASVLHQNSGLTLSVTPEGIRSLAALRSTLHVVFRVFILGARAESSLPPHVWEQ-LSMLFPLHLHFIGPQSLDPYTDVFFLFSPGLGTLPLLLQSKCAIFVTGFSPADVERDVRSLVVTPGENAFGSEKWEVADFDPRNWGIWGIRGKRR Fusgr1 DDLFHPFSKSPVPEFRQRAAFMRQHAYCPHVNFECPDCGLPVYCCEEHWLRQINEDDHDLRSGRVFEEGN-LPHAAINMTNWDTFMYTREFDAVNSDRQMRQITRLLTYPVTIGSVLHELSPYSIKVTTEGLKSFSALRYNLHPAVRVFILGARAESSLPRPAWVQ-LAHMFPLHLIFVGPEPYDPYFDCFVLFHPGLGTLPLLLETKVPIISTGYTQFDMERDVEWVLLQPGENTFRSLRWDLNDMDPQNWGVWAFRGKRY Galma1 DNLFHPFSKSPFPAVRARGDAIQKLAPCPAVKFECPDCGWPTHCTEEHWLREANEDEHDLRSGRRMREFE-MPEETVSLGNWDVFWYTRNFPSMDTERSRRHASKLLTYPITIGGTLHQHSGLTLRLTPEGSRSLAALRSTLHVQVRIFILGARAESSLPPHVWEQ-LCMLFPFHLFFIGPQTLDPY------------VLPMLLASKCPIFVTGFSPTDVERDVRSLVITPGPNNFGSEKWEVADFDPRNWGIWAIRGRSR Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 DNLFHSLSESPFEDLRHRYKQICVYGSCPVPKYECPDCGYPTHCSLEHYLRQANEDEHDLRSGRTMIEFD-FPDEQVNMLNWDLFFYTRGFPSMDNDRSVRHVSKLLTYPITIASILHEYGPYNIKLTDEGLKSLTALRTIIYPIIRIFVLGARAESLLPLHIYSQ-LSYLFPFHIYFIGPEPFDPYTDVFFLFSPGISTIIKLLQTKCAIFITGFDQEDLHSEVSAILLRPGENVFKSMKRDIDLKDVRNWGIFGIRGKKY Hisca1 DNLFHSFTNSPSPEIRQRAAFIKQNAFCPHSQFECPDCGVPIYCSEGHWIRQINEDDHDLRSRRFFSEFN-YPDSIVNMTNWDTFLYTRQFDAINNDRHMRQVTRLLTYPVTIASVLHELSPYNIRLTPEGLKSLSALRYTLHPPVRIFILGARAESSLPRDVWLQ-LSYLFPINLIFIGPEPYDPYFDCFMLFHPGLGTLPHLLQTKVPILCTGYSEWDMQRDMDWVLLEPGENKFRSLRWDLNDMDPHNWGLWGFRGKRY Klula1 ENRFHPWDQSPSPDLRERAARIKAMATCPVIQFTCPLSGIPTHHSREAWLKKVNIYEHDLRSGRPFPEFD-FPDRMVNMSNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSVLHQYSPYSLNITLEGLKSLAALRYTLYPPIRIFILGTRAEAQLPGHVWKQ-LQYLIPIELHFVGPEPYDPYNDVFFCFHPGFATMKALMQTKCAVFTTGFSKEDLLRDISIVLMEPVPNVFGSTKWELNDTNPHNMYIAGFRGKRY Lacbi2 DNLFHPFSKSPFPQIIARGEAIKSLAPCPVVSFECPDCGWPTHCTEEHWLREANEDEHDLRSGRRLREFE-LPEEAISFANWDVFWYTRGFPSMDTERARRHASKLLTYPITIGGVIHQHSGLTLSLTPEGSRSLAALRSTLHVQVRIFILGARAESSLPPHVWEQ-LCMLFPFHLFFIGPQTLDPYSDLFFFFSPGFGVLPMLLASKCSIFVTGFSPADVERDVRSLIITPGPSTFGSEKWEVADFDPRNWGVWGIRGKSR Lenti61 DNLFHPFSQSPFPAIRARGEAIRQLAPCPVVAFECPDCGWPTHCSEEHWLREVNEDEHDLRSGRKMREFD-LPEAAISFSNWDVFWYTREFPSMDTERSRRHASKILTYPITIGSVLHQYSNLALSLTPEGSRSLAALRTNLHVQMRIFILGARAESSLPPHVWEQ-LCMLFPFHLYFIGPQTFDPYTDCFFMFSPGLGVLPLLLASKCPIFVTGFSPADVERDVKSLVITPGPNAFLSEKWEVADFDPRNWGIWGIRGKRR Malgl1 DNLFHKLSESPIPSMRARGDRIRSLAPCPVVNFECPDCGWPTHYSENEWLREANEDEHDLRSGRPMTEFQ-LPEAAVNLSGWDQFFYTRNFRSIESDRSKRHVSKLLTFPLTIVGALHEHSPYTRRLTHEGLRSLAPLRQTLHPPVRIFVVGARAESTLPPDVWNQ-IAYVFPIHVILIGPEPFDPYTDVFFAFAPGFGALGQLLSTRCALYISGFSPADVERDVLAFLVTPGENVFASQQWAIADFDPRNWGLWAVRGKRY Mellp23 DDLFHPLSSSPVPAMRQKAERIKASAWCPIVAYDCPESGYPTHSSREAWLRESNEDEHDLRSGRPMNEFD-LPEEAITLSNWDLFLYTRGFRSIDEDRSRRHISKLLTYPISIGAVLHEFSPYSTRLTTEGYRSLTALRQSLHPPIRIFVLGARAESSLPPAVWAQ-LPFLFPFQIFFIGPEPFDPYNDVFFAFSPGFGDVKMILDTKCALFAGGFSPADVERDVEAILLHPGENVFASQRWEVAEFDPRNYAIWGIRGKRY Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ADLFHPLSKSPLAPVRAKAEWIAAHGTCPVPTYECPDCGYPTHCSEEHYLREVNEDEHDLRSGRRMKEFE-FPDEAVNLSNWDTFLYTRGFLSMNSERSMRHVSHVLTYPLTIGSVLHQSSPYQLGLTVEGLKSLAALRHTLHPTVRIFCLGARAESHLPPHIYMQ-LAYLFPFQIHFVGPDPFNPYYDVFFLFSPGLATIPLLLDTKCAIFGTGFDERDVMNDVAEILMKPRENVFRSLKHEINMTDVRNWGIWGIRGRRY Mucci2 DNLFHVLSRSPLPEMKDRAAIVNKYGVCPVPTYDCPDCGYPTHCSEEHYLREINEDDHDLRSGRPMREFE-FPDEAVNMANWDVFFYTRSFPSMDSDRSMRHVSKLLTYPMSIAAVLHQSSPYKYGVTAEGMRSIAALRTILYPTINVYLVGARAEATLPSHIWLQ-LAYLFPFHIHFIGPDKFDPYTDLFFLFSPGIGSIEKALETKCPIFVTGYDEADMKNDVEAVVLKPTVNEFRSLKRDVNLMDLRNYGIWGIRGKRY Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 DNLFHSFTNSPIPKIRQRAAFIRQHASCPHVDFECPDCGIPVYCSEQHWLRQINEDDHDLHSGRHFYEFN-YADAMVNMTNWDTFMYTRQFEAVNDDRCMRQATRLLTYPLTIGSVLHELSPYHIRLTVEGLKSLTALRYTLHPPVRVFILGARAESSLPRDAWVQ-LAHLFPLHLIFIGPEPHDPYFDCFVLFHPGLGTLPMLLETKAPIIATGYTQADMERDVEWVLMEPGENIFRSLRWDLNDLDPQNWGVWAFRGKRY Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 DNLFHSFSNSPSPAIRKRAEFIKQNAFCPHSHFECPDCGVPVYCSEGHWLRQINEDDHDLHSGRFFREFH-YPNFVINMTNWDTYLYTREFAAINDDRSMRQVTRMLTYPQTIGSVLHELSPYSVRLTPEGLKSLSALRYTLHPPVRIFILGARAESSLPRDVWLQ-LQYMYPLHLIFIGPEPFDPYLDCFMLFHPGLGTLPQLLETKVPIICTGYTQWDLERDINWVLLEPGENIFRSLRWDLNDQDPHNWGLWAFRGKRY Phybl2 DNLFHKLSESPIPELRERGSYISKYGVCPVPVYECPDCGYPTHCSDDHYLREQNEDDHDLRSGRTMKEFE-FPDEAVNMSNWDVFFYTRSFPSMDSDRSMRHVSKLLTYPVTVASILHQSCPYKLGITPEGMRSISALRSILYPTINLYVVGARAEASLPQHIWLQ-LAYLFPFHIHFVGPDKFDPYTDLFFMFSPGIGSITKALETKCSIFLTGYDQADMLNDIEAVVLKPTTNEFRSLKRDVNLADLRNWGIWGIRGKRY Picst3 ERPLYNWDESPYEDIRTRAAFIRAKALCPVVNFVCPYSGIPTHHSREAWLKKVNLYEHDVRSGRKFDEFV-FPDYMVNLSSWDSFFYTRDFAPMNTEFNLAAATKVLTYPMTIAAIINKYSPYEPQVTVEGLRSLAALKYTLYPPMRIFILGAKMESMLPGYVWKQ-FGYLFPFEIHLVGPEPFDPYLDIFFLFHPGFGAMKGLLESKCPIYVSGYHDKDMKREIQWLLMTQTDNKFACTKIDLVDINPTNSQLYAFRGKRY Plicr1 DDLFHSFSKSPFPAVRARGEAIQSLAPCPVVKFECPDCGWPTHCTEEHWLREVNEDEHDLRRGRRMREFD-LPEEAVSFANWDLFWYTRGFPSMDTERSRRHASKLLTYPMTIGNVLHQHSGLSLSVTPEGSRSLAALRTNLHVQVRVFILGARAESSLPPHVWEQ-LTMLFPLHLFFIGPQTFDPYSDCFFMFSPGFGVMPALLASKCPIFVTGFSPADVERDVRSLVITPGPNAFGSEKWEVADFDPRNWGIWGIRGKTR Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 DDLFHPLTSSPIAAMREKAGRIKSIARCPVVAYDCPECGYPTHSSREAWLREANEDEHDLRSQRPMLEFD-LPEETITLANWDLLLYTRGFRSIDEDRSRRHVSKLLTYPMTIGAILHEFSPYSTRLTLEGYRSLTALRQSLHPPIRIFILGARAESSLPPAVWAQ-LPYLFPFQVYFIGPEPFDPYTDVYFAFSPGFGDVKLILDEKCALFGAGFSPADVQRDVDALLLNPGENVFASLKWEVAEFDPRNYAVWGIRGKRF Punst1 DDLFHPFSKSPFAAVRERGEVIRKLAVCPVVEFECPDCGWPTHCSEEHWLREVNEDDHDLRSGRRLIEFE-FPEAAISFANWDTFWYTRGFPSMDTERSRRHASKVLSFPITIGSVLHQYSYLTLNLTPEGSRSLAALRQTLHVKARIFILGARKESSLPPHVWEQ-LCLLFPVHLYFIGPQSYDPYTDVFFIFHPGFGVLPALLQTKCAIFVTGFSPADVERDVRALVLTPGPNAFGSERWEVADFDPRNWGIWGIRGKRT Rhior3 DNLFHVLSKSPLPEMRDRASMIKKYGTCPVPTYDCPDCGYPTHCCEEHHLRQVNEDDHDLRSGRSMKEFE-FPDEAVNMANWDVFFYTRSFPSMDSDRSIRHVSKLLTYPITIASVLHQATPYKYGITAEGMRSIAALKTVLYPTVNIYLLGARAEATLPSHIWLQ-LAYLFPFHIHFVGPDKFDPYTDLFFMFSPGIGSIEKLLETKCPIFITGYDESDMDSDIKAVILKPTVNEYRSLKRDVNLMDVRNYGIWGIRGKRY Rhoto1 DNLFHPLSQSPFPEMRAKGERIKQLAYCPVVAYECPNCGFPTHASEERWLREANEDEHDLRSGREMTEFR-LPEQAVSMGNWDVFLYTRGFPSIDTERARRHVSKLLTYPITIGSVLHENSPYTIRLLPEGLRSLLALRRTLHPPLRIFILGARAESSLPARVLAQ-ISHLFPLHIVFIGPEPFDPYQDVFFAFSPGFGAVLSILETKCALFCTGFSPADIERDVVALLLTPGENVFGSEKWEIAEFDPRNWGVWGIRGKRY Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ENRFHPWDQSPSVDLRERAAKIRTLAHCPVINYTCPLSGIPTHHSREAWLKKVNIYEHDLRSGRPFPEFD-FPDKAVNLTNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNITLEGLKSLAALRYTLYPAMRIFILGARAEAQLPGHVWKQ-LQFLFPFEIHFIGPEPYDPYMDVFFTFHPGYATMKALLETKCAIFTTGFNKKDLTDDINLVLMEPVRNVFGSTKWELNDMNPQNMYIAGFRGKRY Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 DDLFHPLSKSPFPEVRARAEVIQKLAPCPVVAFECPDCGWPTHCSEEHWLRDANEDEHDLRSQRRFREFE-MPEDAISFANWDTFWYTRGFFSMDSERSRRHASKVLSYPITIGNVLHQYSNLTLNLTPEGSRSMAAIRSTLHVQVRVFILGARGESSLPVHVWEQ-LTMLFPLHIIFIGPQTLDPYSDCFFLFSPGLGVLPTLLETKCPIFVTGFSPADLERDVRALILTPGPNEFASLRWEVADFDPRNYGIWGIRGKTR Schpo1 HELFHPLSRSPLTALRRRSEHIKQVYRCPIVEYECPESGFPTHCNRTHWLRQINEDYHDLARPNPLPELLKLPDEVVSLLSWDSFFYTRDFPKFQSSRTARHITSLLTYPMSIGAILHKNSPYNLKLTPQGLQSLTALRYMLHRPTRIFVLGATKECSLPPSIWLQGLNFLFPFQLHFIGPEPFDPYYDTFFLPMPLISTLHDLVSTRCSVWLTSPSSQRTTKDLEVLLLLPTVNKFASLGWSVDDSNLHNQEVFGFRALYY Sorma DNLFHSFTNSPIPKIRQRAAFIKEHASCPHVDFECPDCGIPVYCSEQHWLRQINEDDHDLHSGRHFYEFN-YADAMVNMTNWDTFMYTRQFEAVNDDRCMRQATKLLTYPLTIGSILHELSPYHIRLTVEGLKSLTALRYTLHPPVRLFILGARAESSLPRDAWVQ-LAHLFPFHLIFIGPEPHDPYFDAFVLFHPGLGTLPMLLETKAPIIATGYTQADMERDVEWVLMEPGENIFRSLRWDLNDLDPQNWGVWAFRGKRY Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 DDLFHPLSQSPFKEMRQKGDRIKQLAYCPVVQFECPNCGFPTHASEERWLREANEDEHDLRSGRELTEFK-LPEEAVSFGNWDVFLYTRGFPSIETERSRRHVSKLLTYPMTIGSVLHENSPYTLRLLPEGLRSLVALRQSLHPPVRIFILGARAESSLPAHVLQQ-ISHLFPLHIIFIGPEPFDPYQDVFFTFSPGFGSILSILETKCALFVTGFSPTDIERDVVALLLTPGENVFASEKWEIAEFDPRNWGIWGIRGKRY Stehi1 DDLFHPFSQSPFPAIRARGEAIQKLAPCPTVKFECPDCGWPTHCSEEHWLREVNEDDHDLRSGRRIQEFE-LPEAAISFANWDVFWYTRNFPSMDTERSRRHSSKLLTYPLTIGSVLHQWSPLMLSLTPEGSRSLAALRLTLHGQVRIFILGARAESSLPPHVWEQ-LCLLFPFHLFFIGPQTFDPYTDLFFLFSPGFGEIPLLLETKCPIFVTGFSPADVERDVKSLVITPGPNTFGSEKWEVADFDPRNWGVWGMRGKRR Tapde11 ------------------------------------------------------------------------------MTSWDSFLYTRHFNAVNSERSIRHVSKLLTYPMTVASVLHQGSPYR--LTKEGLRSISALRATLHPPFRIFVLGARAESTLPGDVWIQGLPYIFPFHIHFIGPEPFDPYLDVFFLPCPGLGTMPAILESKCGIFVTGYSEEDMKRDIRFILLRPGKNDFASRKWDVSDLDPRNWGVFGVRGKLY Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 STLFHLLSQSPSSALREKADRVKAHSLCPVPKFDCPNCGWPTHASEQRWLREVNEDEHDLRSGRKMKEFESMPEAAINFSSWDTFFFSRNFPSIDNDRAIRHVSKILTYPITVGAILHQNGPFTSGITREGQRSMAAFHSILHLPFRIFLLGARAESTLPPDLWSQ-LTFLFPLHIYFIGPEPFDPYSDVFFAFSPGLGPLQQILGTKCALFFTAFSPLDLQRDVSALVLTPGINPFGSIKWEIAEWDVRNWGVWGIRGKRY Trire2 DDLFHPFSESPVPEFRRRAAFMRQHAYCPHVDFECPDCGIAVYCSKEHWLRQINEDEHDLRSGRVFHEGN-LPNAAVNMTNWDTFMYTREFEAVDSDRSMRQITRLLTYPITIGSVLHELSPYTIQLTVEGLKSFSALRYNLHIPVRLFILGARAESSLPRPIWVQ-LAHLFPLHLIFIGPEPYDPYFDCFVLFHPGLGTLPLLLETKVPIISTGYTEVDVKRDVEWVLLEPGENIFRSLRWDLDDMDPQNWGVWAFRGKRM Umbra1 DNLFHPLSESPIPEIRDRATIIKKYGTCPVPEFECPDCGHPTHCCEEHYLREHNEDEHDLRSGRPMKEFE-FPDEAINMANWDVFFYTRSFPSMDSDRNMRHVSKLLTYPITIGSVLHESSPYK--VTPEGLRSLAAIRSILYPTVNLYLLGARAESTLPPHIWLQ-LSHLFPFHLHFIGPDSFDPYRDIYFLFAPGIGSIAKALDTKCAMFITGFDQTDVQTDVKAVILKPTENHFKSLKHDINLQDLTNWGIWGIRGKRY Ustma22 DNLFHPFSKSPIASIRARGERIRSLAPCPVVNFECPDCGWPTHYSEKEWLREANEDEHDLRSGREMSEFK-LPEETINMSNWDVFFYTRNFNSIESDRSRRHVSKLLTFPTTMAAVIHENSPYTKKLTHEGLRSMIALRQTLHPKMRIFVVGARAESTLPPAVWDQ-LTYMFPLHLFLIGPEPFDAYTDVFFAFSPGFGAIGQILSTRCALIATGFSPADVERDVLAFLITPGENVFASQQWAVADFDPRNWGLWAVRGKRY Walse1 KTLFHPLNESPIPSLRALGERISNKGKCPILKYYCPISGYPTHSSKEAYLREVNEDEHDLRSGREMKEFE-MPEQTVNLKSWEMLFYTRNFNSVDNLRSQRHLSRLLSYPMTIAGILHELGPYADRVTPHGERSLLALRYMLHKPIRIFIPGARAESQLPSSVWMQ-LAHLFPFQIYFVGPEPFDPFTDIFFNFHPGLGALDKMLETKCPIILTAFSPSDMKRDFDALVVEPGDNVFGSQRWEVAEFDTRNWGLWGIRGRRF Zygro1 ENRFHLWDQSPAGDLRERAARIRALAQCPVINYTCPLSGIPTHHSKEAWLKKVNIYEHDLRSGRPFPEFD-FPDRTVNMTNWDLFFYTRQFYSMDTEFQLAAVTKMLSYPITIASVLNQFSPYSLNITLEGLKSLAALRYTLYPPMRLFILGARAEALLPGHVWKQ-LQFLFPFELHFIGPEPYDPYLDAFFCFHPGFGTIPGLLETKCAIFATGVNKSALLRDINAVLMEPTKNIYGSTKWELNDVNPQNMYIAGFRGKRY [Cluster3395.fasta_al_trimmed; alignment length = 37] Allma1 YQVRASVKPRCEHCYVVVRKGR-RYVLCKKSTRHKQR Ashgo11 FKVRTSVKKFCAHCYIVRRKGR-VYVYCKSNNKHKQR Aspfu1 ------------------------------------- Aurde31 YKVRSSVKKLCDGCYTVRRRGV-LFIQCSRNPRHKQR Batde5 YKIKTALRRRCEHCYFVARKGK-LRIVCPENGKHKQR Botbo1 FKVRSSVKLFCDGCSVVRRKRK-LYVICSKDPKHKQR Botci1 MKVRSSVKKLCEGCKSVRRKGH-VYIICSLNPKHKQR Caeel FKVKSRLKLRCRSCYFLRVEGR-LHVECNENPRHKAR Canalb1 FKVRTSVKCMCKDCYLVKRKGR-VYVYCKSNGKHKQR Cangl FKVRTSVKKMCSDCYIVRRKGR-VYVYCKSNKKHKQR Capow ------------------------------------- Catan2 YQVRASIKPRCEHCYMVMRKGR-RYILCKKVARHKQR Cioin ------------------------------------- CocheC53 MKVRSSVKKLCEGCKSVRRKGRYVYIICSKNPKHKQR Coere1 MKVRSSVKLICNSCSFVRRRGR-LFVVCKHDPKHKQR Conco1 FKVKSSVKKRCEHCYMATRKGR-VYVLCKVNPKHKQR Conpu1 ------------------------------------- Copci ------------------------------------- Croqu1 MKVRSSVRRICDGCSVVKRKGR-VYVICSKDPRHKQR CryneH991 MKVRSSVKKFCDGCLIVRRKGR-IYVICSKNPKHKQR Crypa2 MKVYSSIKKRCEHCKVVRRNGY-RYIICSANPRHKQR Debha1 FKVRTSVKKFCKDCYMVRRKGR-VYVYCKSNGKHKQR Dekbr2 ------------------------------------- Dicdi MRHVSALKKLCRFCQTIRRGKN-VFVFCKANARHKQK Dmel FKVKGRLKRRCKDCYIVVRQER-GYVICPTHPRHKQM Enthi ------------------------------------- Falba ------------------------------------- Fomme1 MKVRSSVKLMCDGCAIVKRKGR-VYVICSRNPKHKQV Fusgr1 MKVQSSIKKRCEHCKVVRRNGH-LYIICKANPRHKQR Galma1 MKVRSSVKVMCDGCNVVRRKGR-VYVVCSKNPKHKQV Ganpr1 FRTKSSVKKRCEHCFVVRRRGT-LMVLCKKNPKHKQR Gloin1 MKVRSSVKKFCDGCYTVKRRGR-IFVLCKKNKKHKQR Hisca1 MKTRSSVKRLCDGCKPVRRKNR-VYIICSKNPKHKQR Klula1 FKVRTSIKKFCNDCYMVRRKGR-VYVYCKSNKKHKQR Lacbi2 MKVRSSVKVMCDGCSVVRRKGR-VYVVCSKNPKHKQV Lenti61 MKVRASVKVMCDGCSVVKRKGR-IYIICSKNPKHKQR Malgl1 MKVRSSVKRLCNHCALVRRKGR-LYVICSKNAKHKQR Mellp23 MKVRSSVKRICDGCSVVKRKGR-VYVICSKDPRHKQV Mnele ------------------------------------- Monbr ------------------------------------- Morel2 MKVRASVKKICEGCSSVKRRGR-VFIICSKNQKHKQR Mucci2 ----SMLTLMCDGCSTVRRRGK-LFVTCNKNKKHKQR Mydma ------------------------------------- Neucr2 MKVHSAIKKRCEHCKVVRRNGY-LYIICPANPRHKQR Orpsp11 ------------------------------------- Pench1 MKTRSSVKRLCDGCKPVHRKGR-VYIIW--------- Phybl2 MKVRSSVKKICDGCSTVRRRGK-LFVTCSKNKKHKQR Picst3 FKVRTSVKKFCKDCYMVRRRGR-VYVYCKSNGKHKQR Plicr1 MKVRASVKVMCDGCNVVKRKGR-VYVICSKNPKHKQV Polpo ------------------------------------- Pucgr2 MKVRSSVKKICDGCSVVKRKGR-VYVICSKNPRHKQR Punst1 ------------------------------------- Rhior3 ------------------------------------- Rhoto1 MKVRSSVKKLCSGCKSVRRQGV-LFILCDLNPKHKQR Rozal11 ------------------------------------- Sacce1 FKVRTSVKKFCSDCYLVRRKGR-VYIYCKSNKKHKQR Salro ------------------------------------- Schco3 MKVRSSVKPMCDGCNVVRRKGR-VYVICKKNPRHKQV Schpo1 FKVKASVKKRCSSCYFVRRKGR-LYVLCKKHPRHKTR Sorma MKVHSAIKKRCEHCKVVRRNGY-LYIICPANPRHKQR Sphar ------------------------------------- Spipu1 ------------------------------------- Sporo1 MKVRSSIKKYCEGCSIVKRQGT-LFVLCSRDPKHKQA Stehi1 MKVRSSVKKLCDSCHIVLRKGR-VYVICSVNPRHKQV Tapde11 ------------------------------------- Thetr MKVRSSVRRICAACRVVKRKKK-VFVVCKSNPRHKQR Treme1 MKVRSSVKKFCDGCMVVKRKGR-VYIVCSKNPKHKQV Trire2 MKVHSSVKKRCEHCKVVRRNGY-LYIICKANPRHKQR Umbra1 MKVRASVKKICDGCSTVKRRGK-VFVVCSKNKKHKQR Ustma22 MKVRSSVKKFCDGCSVVRRKGR-LYVICSKDPKHKQR Walse1 MKVRSSVKKMCDGCSIVRRKAR-LYVICSKDPKHKQR Zygro1 ------------------------------------- [Cluster3406.fasta_al_trimmed; alignment length = 59] Allma1 LRQLSCQIFQTVHNPTHARTGHRILRERLAGPHLTSYY-PLRLNKILNARNKGAPKKGE Ashgo11 VAQISARIFDQCYNPSGARIGTKILTKRLRGPAMVQYYGNYRLQMVRKRRGKGAPTKKK Aspfu1 DLETQCRIFSLNFNPQRLRLGNKVLRQRLRGPALAAWY-PDREEAIAKLRGKGRPKKKR Aurde31 MLRLRANIFQTSYNPTNVRTGAKYLKARLRGPSMIAYY-PLRLQDVKKERGKGTPRKAR Batde5 ----------------------------------------------------------- Botbo1 LLQLRSSIFATSYNPRSLRTGAKYLRARLRGPSMTQYY-PQRLEDVRKKRGKGAPKKAK Botci1 LMKVQCRIFSTTFNPDRLRTGNKILRQRLKGPALAAYY-PDRFEHILKARGKGAPKKKR Caeel ----------------------------------------------------------- Canalb1 VRKTSFKIFDQFWNPNAKRNPNKILRAPLKGPEYVKYYGDHRVFIVRKRRNKGAPKKKK Cangl VAELSAKIFDQGFNPSGARTGAKILSQRLKGPAVSSYYGNYRLMMVRKRRGKGAPKKTK Capow ----------------------------------------------------------- Catan2 TAKLSTDIFQTVHNPQHLRTGHRILRERLAGPRLTSYY-PNRLEKILKARGKGAPQKGQ Cioin ----------------------------------------------------------- CocheC53 LMRVQCKVFNTTYNPERLRLGSRILHQRLKGPSVASYY-PDWLEHLAKSRGKGAPKKKR Coere1 VAELSAKIFGNSFNPTGARNGNYILRQNFRGEHMLRYYLSDRLNVIRKARGKSTPKKGE Conco1 LDKIISNIFKTKL-PTIERDGTKFLK-PLIGPKILNYY-PYRVWIARRRRGKGAPKKSK Conpu1 ----------------------------------------------------------- Copci LAKLRCSIFQQTYNPTGVRTGAKYLKQKLRGPAMTMYY-PERIEDVRRKRGKGAPKKAK Croqu1 LAKIQSQVFQTTFNPTGLRTGEKYLTRKLKGHLMKDYY-PKRLDRVNQKRGKGPPKKGE CryneH991 LSSLRSPIFNTISNPTSARMGTKYLRRRLRGPTVASYY-PKRIVRVKKRFGKGPPKKGQ Crypa2 LMQARCRIFATTYNPDGIRTGNKILRQRLRGPALAAYY-PDRLEQILKARGKGAPKKKS Debha1 AKKLSAEIFGNNWNPNNVRNGSNVLRAPLKGPQVASYYGDYRVKMVRKKRNKGAPKKKS Dekbr2 LEKLQCQIFHTTYNPTKQRTGAKILRKPLIGQTMASYYGPYRLERIRKRRGKGAPKKKR Dicdi ----------------------------------------------------------- Dmel ----------------------------------------------------------- Enthi ----------------------------------------------------------- Falba ----------------------------------------------------------- Fomme1 LNRLRCSIFQTSFNPTSRRTGAKYLKSRLRGPSMVEYY-PRRNISIHKDRGKGAPKKAK Fusgr1 -------------------MGTKILRQRLRGPATAAYY-PDRFEYILKLRGKSAPKKKK Galma1 LTKLRCNIFQTTYNPKSLRTGAKYLRARLRGPSMVGYY-PERLQDVRKRRGKGAPKKAK Ganpr1 LLRLRASIFSIPYDPAIRSDGTHILRERLVGPALRSYY-PKRKEKQLEGRNKRKISRAK Gloin1 LAQLSAKIFNNVYNPTGERTGNKILRKRLIGSTITGWY-PLRLEEIRKKRGKGAPKKGQ Hisca1 LVKAQCRIFSHTYNPEQQRLGNKVLRQRLRGPALAAYY-PKRLAVILQSRGKGAPKKRR Klula1 LAEISAKVFDQNFNPTNARTGSKILAQRLKGPAIANYYGNYRLTMLRKRRGKGAPTKKR Lacbi2 LTKLRCKIFQTTYNPQGLRTGAKYLRQRLRGPSMMAYY-PERLVDVRRKRGKGAPKKAK Lenti61 LTRMRCEIFQTSYNPTSVRTGAKYLRARLRGPSMINYY-PERLADVKKRRGKGAPKKAK Malgl1 ----------------------------------------------------------- Mellp23 LNKLQSEIFQTTYNPHELRIGEKYLNRKLKGHLMRSYY-PKR----------------- Mnele ----------------------------------------------------------- Monbr ----------------------------------------------------------- Morel2 LNKISCAIFGNVYNPQGIRTGNKILRQRLIGPTVNSYY-PTRLEDLRKKRGKGPPKKGQ Mucci2 LTQLSCKVFSNVYNPTCARTGNKIIRQRLIGSTLTSYN-PERLDEIRKRRGKGAPKKGQ Mydma ----------------------------------------------------------- Neucr2 LVKARCELFSTTFNPEGIRTGNKILRQRLKGPALATYY-PDRLEHLLRARDKGAPKKKR Orpsp11 ----------------------------------------------------------- Pench1 ----------------------------------------------------------- Phybl2 LAQLSCKIFQTVYNPTSARTGNKVLRQRLLGSTLTQYH-PERLEEIRKRRGKGAPKKGQ Picst3 VKELSSNIFGHAWNPSCKRTGAKILKEELKGPQLVKYYGVYRLHMVRKKRNKGAPKKKS Plicr1 LTKLRSEVFQTAFNPTSQRTGAKYLRARLRGPSMVKYY-PQRLEDIRRVRGKVKPKKAK Polpo ----------------------------------------------------------- Pucgr2 LAKAQSTVFQTPYNPRNLRTGDRYLTKKLKGPLLQTYY-PKRLERVNRKRGKGPPKKGE Punst1 LTRLRCSIFQTSYNPTSARTGAKYLRRRLIGPALLKYY-PQRLMDVRKARGKGAPKKVS Rhior3 LQQLSCKIFSNVYNPTCARTGNKILRQRLLGPTLTAYN-PERLDEIRKRRGKGAPKKGQ Rhoto1 LLKARCDIFGSEYNPDRVRNGAKVLQQRLTGEVKAGYYGPQRREDIKNKRGKFKPKKGQ Rozal11 LHALRCKVRQEINNPNGIRTGERFICRNLLGRYVNHFH-PRR----FELRGKGGEKRKK Sacce1 VAELSAKIFDQNFNPSGIRTGSKILNERLKGPSVASYYGNYRLSMVKKRRGKGAPKKMK Salro ----------------------------------------------------------- Schco3 LDRLRASIFQTSYNPTGVRTGAKYLRNRLRGPSMVEYY-PQRLQDVRKTRGKGTPKKAK Schpo1 LNILSSKIFGTQYKSNNSRTGRKFVVQELKGAKLKSYY-PLRMEIRRIRQGKGASKSKK Sorma LVKARCELFSTTFNPERVRTGNKILRQRLKGPALVAYY-PDRLEHLLRARDKGAPKKKR Sphar ----------------------------------------------------------- Spipu1 ----------------------------------------------------------- Sporo1 VVKLRSEIFGTTFNPDSLRTGSKVLKARLRGPAMLRYY--TRLADLMRKRGKVKPKKGQ Stehi1 LTRLRSQVFQTSYNPSSMRTGAKYLKRRLRGPSMLEYY-PTRLQDIKKARGKGTPKKAK Tapde11 ----------------------------------------------------------- Thetr LVAVSRAIFGTV-EGNGLRSGRKVLRKALVADKMLNYYMPRRKAKALSRSGRGAPKKGA Treme1 LSSIRAPIFNTIHNPTNSRLGNKYLRRALRGPTMVEYS-GWRLEKVMKSRKKGPPKKGQ Trire2 ----------------------------------------------------------- Umbra1 LTRTACKIFSTVYNPTAARSGNKILRERLVGPTVSSYY-PERLDEIRKRRGKGAPKKGI Ustma22 LKALQAKVFGTTYNPTQARTGAKVLRQRLQGPSMLAYY-PQRLKDVKKMLGKGPPRKGE Walse1 ----------------------------------------------------------- Zygro1 VAELSAKIFDQNFNPSGVRTGSQILAKRLKGPAVASYYGDYRLTMLRKRRGKGAPKKKK [Cluster3408.fasta_al_trimmed; alignment length = 206] Allma1 GNPVTLPAKLLVADAGFSARIVSAETGASLIVFKGHTGPVTSTAYVFTGSWDK--SVKKWSVKTGACVSTLHQDFVKSLALTLYSGSSDKTIRQLNLASVMLKG-HTRGVEDLS-CSSDGSIRKWETGHDTSVYALASADKSVKLDHADYVKALATGCREKIRIFDI-DGHFDEVSALLYSGSLDCTLRSWSVLTEE--EERELAE Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 GSPIKLQSKVFVALSTGTVRKIILETGETAAVFKGPTAPVTSVCFLFAGCWDK--TIWSWDVASGQPQHRGHTDFVRSVISLLVSGGADAQILVFDIALYTLKG-HAKGVQDLS-AGSDREIRWFDIAHDTSVYKLASADKTAKLPHPDFVRDVITACREEVRVWHF-SGHFEEVTRLIVSVSIDATIRQWSLLTEE--EERELAE Aurde31 GQPIRLPSKVWTAESSHVLRKTHLETGATVQLYRGHEGPVSALAFVITGSWDK--TIRVWDANSKALLSTAHRDFVKSLLVLLASGSSDKSIRFWDMSLGSISS-HTRPVECLS-ADSAGTIKVWRLGHRTGINEMASTDYTVQLEHPVAVKCVFTGAGDSIRAYDI-DAHANDVTSLIVSGSLDGTLRKWNLLTAE--ELADLED Batde5 GFPLQLPSKAYVGESGHVARKINLQSGAMIRVFKGHSGPVTSLAILFTGSWDK--TIRKWNTENANQLFCFHNDFVKSVCLVLYSASTDKTICQWDGNVKTMRG-HTRGVETIS-ASSDGSIRKWDTGHDTSVYGLASADKTARFEHPDFVRSVITGCRENMRMWNI-EAHTGEVSSIILSGSLDNTIRFWSIISEQ--EERELAE Botbo1 GSPIELKGKAWTAESGGVARKVELETNKTLQIYKGHDGPVTTLDFLITGAWDK--HINVWNTKTKALVSSAHGDFVKKVLVLLVSAGSDKLVKLWDLSVGSLSA-HTRPVEALT-GDTMGIIKVWSLGHRTGVTAMASLDSTVIIHHKYQCRALLTGSADTIKIWDVDDGHWHDITTMIVSAGLDGTIRRWKLPTEEEVENADFGD Botci1 GNPIVLQSKIYIAESAGCVRKVNTETRDTKTVYRGPTAPVTSVAILFAGCWDK--QIWSWDRESKDLGKKGHSDFVKAIVCCLISGGADAKIMVWNTALHTLRD-KSEAVQDLS-SSSDPHIRRWRIEHETSVYQVASADGTAKYEHGDYVRAVVTAGREDVKIWDY-DGHYEEVTGLAISTSIDGTVRIWGLMTAE--EEAELAE Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 GNPRQLPSKLLITDAGHMIRIVDAESGKSIATFKGHTGPVTSAVYIFTGSWDK--SIKKWSLATRECLATLHRDFVKSLTLHLASGSSDKSIRILDLASRTLLG-HTRGIEDLS-GGSEGSIRKWDLGHHTSVYALASADHEVKLEHADYVTAVFTGSREGIRVWDI-DGHFDTVTALLYSCSLDGTLRSWKLLTAE--EEAELAE Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 GNPTKLPSKVYVAEAAGSVKHINIETSKVIATFSGPTAPLTSIAVLFAGCWDK--SIWSWSLSSRKASTRGHSDFVKAIISVLVSASQDASIIVWDVALHTLKG-HTRGILALS-AGSDREIRRWQISHETSIDALASADKTAKFEHPDFVRDIVTACREEVRVWEF-SGHFEEVTGLLISVSIDATVRQWSLLTVE--EEAELAE Coere1 GSPIRTKARAVLALASHQAKVADLKAAACVKAAVKHAGPVTSVAVAMSASWDK--VIKVWAVDPQRTLAVGHSDFVKCLVAIIYSGSADKSIMFWRLPFKVIKGEHTGQIYTLS-AGSDASIRAWDSQHKTNIFDCASADKTAVLEHSTAVTAVVTGVRGAIYVWRI-HAHTDDVTCLFYSSGLDETLRKWDILTEE--EERELAE Conco1 GDPVDLKSKAILAHSTGTIRFFGLKDKETKKLIRAHTTPVTCLDILASGAWDK--TIKIWDIKTGKLLHTGHNDFIKTIKFTLYSGSSDGDIRLWSISQAVMKS-NSGTIENLSCGSGDLSIKQWDLGHLTTVYRIASADKTIKFDHDDTVKSLLTGGREKVYLWNY-QGHWDEIMGLVISTGLDGTIRYFDI-------ESKFIN Conpu1 GFAINLPGKAWIAESGHVIKKIDLKARKTVQVYRGHSAPVTCVELVVSGSWDKATTIKIWNTETKEPLSTAHDDFVKTLFSLLISSGSDKIVRFWDMSMGSISA-HTRPVECIT-GDTMGIIKVWKLHHRTRINGLASADETVQIALPQPVRALAVAFGDIIRLYDV-DGHWHDVTALIVSASLDGTIRKWRLLTEE--EERELAE Copci GEPIELPGKVWIAENDHVVKKLNLEARKASQIYRGHTGPVTSIAFLISGSWDK--SIRVWDTQVRPLATTAHNDFVKTLLVLLVSGGSDKIVRFWDLSSGSISS-HTRPIECLT-ADTMGIIRIWEVNHRTRINDLASSDDTAQIEHPTAVRALLTASGDVIRVYDT-DIHWHDVTAIIVTTSLDQTVRKWRLLTEE--EERELAE Croqu1 GYPIVLASKVYVAQNGFVAQRIDLKTGKVMSIFRGHAGPVTSIAILITGSWDK--SIKVWDIETQIQLSSVHRDFVKSIEVLLASGSTDRDILLWDLRVDTLKS-HTRPVDALS-GDTMGAVKVWHLLHHTSINSIASSDNSVLLTQPYYIRCLLTGSTEDIRVYDV-KAHWHEVCSLIISGSLDGTLRKWEILSAE--E------ CryneH991 GSPITLSSKAFTAESGWQARRVDLKTGKTIRLYRGHQGPVTSVALLLTGSWDK--TVRVWDTDTGAHLQTGHTDFIKSVTVLLLSTSSDRTCRLWDISSQILKE-HTRPVECAT-GDSLGVIKKWKVGHETSVAKLVSMDKMAIIPHNSYVKSVLTGSEEDIRVWDI-QGHCAEVSDIVVSAGLDATLRTWTVLTEE--EERELAE Crypa2 GTPIALKSKVFVAESVGSVRRINIDIDDTNMVYRGPSAPVTCVVVVFAGSWDK--NIWSWNIETRRPGIKGHSDFVKAVACVLISGGADKKIIVWDIALHTLQD-SVTAVQSLS-AGSDPHLRRWKVVHETGVYKIASADGTARLEHGDHVRAIITAGREDLKCWDL-EGHYDEVTDLLVSVSIDGTVRVWPLLTAE--EEAELAE Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba GHPVRLAAKLFLGLADCTIVRLDLTTMDPASALVGHTGPVTGLAHLASASWDR--TVRLWDPATGECLAQGHTEFVKAVCVVIWSSGTDGALRAWALVREVLQVRFGRSLEGLSVGTSLGQVHRFSLRFETNVTHLSLADGTSVLDHTILARSLLAAVGGRIFLWDI-QAHGDAVSGLLISIGLDATVRFWRPATSDE-EEQEQDQ Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 GEPIVMKSKVFIAESAGAVRRINLETSELKTTYRGPKAPVTCVSIVFAGSWDK--DIWSWDVETGKSGRKGHLDFIKTVVCILISGGADKKIFVWDVELHTLQD-PTTAVQHIS-ASSDPHIRRWKIEHETSIYRLASADGSAKYEHGDYVRGVITAGREDVKIWDL-IGHYEEVTDIVCSVGIDGTIRTWPLLTAE--EEAELAE Galma1 GEPIELPGKAWIAENTTVVRKLDLQSGKTLQLYKGHTGPVTSLAFLITGSWDN--SIRLWDTVTKEQISCAHADFVKSFHVLLVSGSSDKIVRFWDISIGSISS-HTRPVECLT-GDTMGIIKAWDLHHRTRINELASADDTVRLTHPVAVRALITAAGDVLRTYDV-DAHWHDIIAIIVTASLDKTIRKWKLLTDE--EERELAE Ganpr1 ------------------ARFYSRQDGTTKALFKGHKGPVTCIAALWSGSWDK--SIIKWDLATNAAVLTHHTDFVKSIIHFCVSCSSDSTIRYF---LRVLKQ-HTRSVEALS-ASSDTTIRKWALGHLTSVYGVASADKTARFEHPDFVKALFTGGRQDIRVWDI-LGHFDEVSVLLWSGSLDGTVRRWTVLTEE--EERELAE Gloin1 GDPIECTSKAYIGESGFIAKRINLLTGKTTKVFKGHTGPVTCLGLLITGSWDK--TLIKWNTKTKESIHTAHTDFVKSLAIILYSGSSDNFIYSWNLVLQKFKG-HSRGIEDLS-ASSDGYIRKWNAGHLTSVYALASADKTVKLAHPDFVKCVITGSRENIRIFEF-EGHFDEVACMLYTGSLDCTIRKWSILTEE--EERELAE Hisca1 GDPIKLQSKVYVAESAGLLRKVVLEVGETATLYRGPTAPLTSICFIFAGCWDK--TIWSWDVTSRTQKHRGHTDFVKTVIS--------------------FDD-YSRGVLHLS-AGSDRSIRYFSLEHETSVYKLASADKTAKLDHPDFVRDVVTGCREEVRVWNF-SGHFEEVTGIVVSISIDATIRQWSLLTEE--EERELAG Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 GEPLELPGKAWIAENTTVVRKLDLESGKTLQVYKGHTGPVTTLAFLITGSWDR--SIKLWDTDTKQLISSAHSDFIKTFFVLLVSGGSDKIVRFWDLSVGSISS-HTRPVECLT-ADTMGVIKVWNLHHRTRINEMASADDTVQIAHPVAVRALITGAGDVLRVFET-DAHWHDITAIIITTSLDRTVRKWRLLSEE--EARELAE Lenti61 GSPIEITGKAWITENTTVIRKLDLETGKTLQLFKGHTAPVTSLAFLVTGSWDK--TIKVWDVKTKELVSSAHSDFVKALHVLLVSSGSDQVVRLWDLSVGSLTD-HTRPVESLT-ADTMGIIKIWDIHHRTRVNDMASTDETVHIEHPTAVRTLLTGSGDVIRVYDT-DAHWHDVTALIVSASLDGTLRRWKLLDED--EERELAE Malgl1 GSPIWLGRGLWTAESGRIARCTNLETGETVQQLCGHMGPVSGVATICTASWDR--SIRIWPSGKPPCIALAASDLLKALHILLYSGGNDKVVRAWDLSVGVLQGAHTRPIVCIT-ADSMGRILQVNMGHETSVHAIASSDQTVRTPHKAHV--VLLGMEGTLQVYR--EGHWHTVTYVIVSASLDGTIRRWPMLTAE--EEAELDE Mellp23 GYPMVLASKVYVAQNGFVAQRIDLKTGSVKGTFKGHAGPVTSIAILITGSWDK--TVKVWDVETQIQLSSAHQDFVKSLEMLFASGSTDRDILLWDIKVGTLKS-HTRPVDALS-GDTMGALKVWCLLHQTSINSIASSDHSVLLEQPYYIRCLITGSTEGIRVYDV-DAHWHEVTSLVISASLDGTLRKWEILSAE--EEAELAE Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 GQAIKVSSKLFTAESGHVARKINLETGKTMKLYHGHTGPVTRVVVLITGSWDK--TIRVWDTESKTCLATGHTDFVKALAVELFSASYDGTILHWDLEGGPWKG-HARGINDLS-AGSDGTIRKWDIHHETTVYRVTSADKTAQLWHPDFVKSVVTGGRESVRVWSI-KGHFDEVSSMLITGSLDNTVRRWSLMTEE--EERELAE Mucci2 GDAIKLASKMYVAESGFQVRKISLATSKTVKLFKGHKGPVTSVIVLWTGSWDK--SIKQWDLVSGECIATGHTDFIKSLVLFLYSGSSDCFLRRWDTRTAVEKK-HKRAIESLS-ASSDGTVLKWDLGHETSIYCVASADKTVRLTHPDRVKSIVTGSSDDIRVWDI-EGHFDEVCCLLYSGSLDCSIRKWSLMTEE--EERELAE Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 GNPIKLKSKIFVAESAGSVRRVQVDGEDTKTVYRGPTTPVSCVAVVFAGAWDK--NIWSWDIDTKAPGRKGHSDFVKAIVCVLVSGGADKKIIVWDIALHVLQD-SVVSIQDLS-ASSDPHIRRWKIEHETTVYKLASGDGSAKFEHGDHVRAVITAGREDLKVWDL-EGHYDEVTELVCSVSIDGTIRTWPLLTAD--EEAELAA Orpsp11 GEPIKITSKAYIAESGFIIRKVNLETGKFVKTFKGHKGPVTCIDIILTGSWDK--TIKKWDVK----------------------------------------------------------------------------------------------------------------------------------------------- Pench1 GNPIRLQGKIYVAQSNGTVRRIILATGETARVFTGPMAPLTSICLLFAGCWDK--AIWSWDTVTGHPRQKGHADFVRSVTSLLISGGADAQILVFNIALETFKG-HSRGIQDLS-AGSDREIRQFSIPHDTSVYKLASADKTAKLEHPDFVRDVVTACREEVRVWNF-SGHFEEVTGLIVSVGIDATIRQWSLLTAE--EEAELAE Phybl2 ------------------------QTKKTNKLFKGHTGPVTSLALLWTGSWDK--TIKKWDTNTGECLLTGHTDFVKTILLKLYSGSSDNHIFQWDISTNVFKG-HSRPVESLS-ASTDLTIKKWDIGHETSIYCVASADKSVRLTHPDRVKSIITGASDLIRVWDI-DGHFDEVSALLYSVSLDCSLRRWSI------------- Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 GSPIQLAGIAWIAENTTVAKKIDLETGKILQIYKGHTAPVTCLAFLITGSWDK--TIKLWDTETKAVISTGHEDFVKALFVILVSGSSDKVVRFWDLSVGSISS-HTRPVESIT-ADTMGIIKAWNLNHRTRVNEMASSDDTVQIPHPVAVRALITGAGDIIRVYDV-DAHWHDVTALIVSASLDGTIRKWRLMSEE--EERELAE Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 -----MTSK----PKHFVAQRVNLKSGKVKATFRGHAGPVTSLAILFTASWDK--TIKTWDVETQVLLSTGHVDFVKSIHILLVSGSTDRDIRLWDFKLGTLKS-HTRPIDSLS-ADSMGTLKVW-LPHKTSINDIASADNSVLIEQPYFVRCLITGSTEDIRIFDL-KAHWHEVNCLLVSSGLDGTLRKWELLTAE--EEAELAE Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 GDAVKLASKIYIAESGFQVRKMTRSTMKSVMLFKGHQGPVTSIVTIWTGSWDK--TIKKWDATTGECLATGHTDFIKTLVLSLYSASSDCFLRRWNIQTAAEKK-HKRPIESLS-ASSDGVMMKWDTGHETSIYCVASADKTVRLEHPDRVKSIVTGSSDDIRVWDI-EGHFDEVSSLVYSGSLDCSIRRWPLLTEE--EERELAE Rhoto1 GQPIKLATKAWVAESGFVVRRVGLETGKTKQIYRGHNGPVTSVAFLISGSWDR--SFRVWDVQTKTHLSTGHIDFVKTLTVILVTGSSDKDIRIWDLSLFALKA-HTRPIEQLS-ADSMGAVKVWELHHELGIYDMASADNSVLIPHPAQTRSLLTGSSELIRIFDI-EGHTHEIVQLILSASLDGTLRRWKWLTEE--EERELAE Rozal11 GDAFECSSQAYTAESAAVVR----KNSQSEKIYKGHTAPVTCLKLIVTGSWDK--KIRLINEKTGNHERVDHSDFVKCMDILLASGSSDKTIVVRSLIVTTIKA-HSRAVEALS-ASSDRTIKQWRLGHVTSVYCLGSADNTIRFEHNDWVKSLIGGSRENMYIWDI-QGHHDQVQRILISVSLDGTLRRWNLMTAE--EEKELED Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 GDPLKLKGVAWIAENSHKIRKLDLETGNTLQLYSGHGGPVTSIAFLISGSWDK--TIRLWNTQDKSLISTAHSDFVKTLFVLLISGGSDKIVRLWDLSVGTIDS-HTRPIQCLT-ADTMGIIRLWELHHRTGVNDLASTDETVQITHPGGVKALFTAAGDVIRTYDV-DAHWHNVTLLLVSASLDNTIRKWRLMTAE--EEAELDG Schpo1 GNPRNLKAKLFVCEASHICKLYDLEINKTCKTYKGHSGPVTCCQIIYTGSWDH--TIKKWNVSTGECVETGHTDYVKCLL-LLLSGSTDASLIVWDVSLYKLTG-HSRGIECIT-CGSESSIRCWHIGHQSNVYCLASADKTVRMEHPDVCTDIATACREEIRVWDY-SGHYESVTKILISSSLDQTIRVWDLLTAE--ELAELEE Sorma GNPIKLKSKIFVAESAGAVRRVQVDGEDTRTVYRGPTTPVSCVAVVFAGAWDK--NIWSWDIDTRAPGRKGHSDFVKAIVCVLVSGGADKKIIVWDVALHVLQD-SVVSIQDLS-ASSDPHIRRWKIVHETTVYKLASGDGTAKFEHGDHVRAVITAGREDLKIWDL-EGHYDEVTELVCSVSIDGTVRTWALLTAD--EEAELAA Sphar DEAVAENKDVQESIEQFMIQGVDLSTI--------------------TGEDDE-EKVFQWDT------------------------ETDKE--------------HIMDRENLQ-------------KYMANVN-------------------VFTGGANSIRKIDT-RKQEGPISALLVTGSWDRTIIVWDAVASSVKSETMYSA Spipu1 GQPIAMPSKAYVAESGHVARKIDLKTGTSLNVFKGHTGPVTSVAVIVTGSWDK--TIRKWDTKTATTILTGHSDFVKRIVIRLYSASSDSTIRQWDLELRVFKE-HTRAVEDIS-ASSDTTIKKWDTGHLTSVYALASADKTAKFEHPDFVRSLATGSRENVRLWDL-SGHYGEVSDILWSASLDGTIRSWSILTDE--EERELAE Sporo1 GNPVQLPTKAFVAESGFVLRRIGLESGKTKQVFRGHSGPVTSLDFLISGSWDK--SFRVWDIQTKSPVSTGHTDFIKTVLVVLVTGSSDKDIRIWDLSVLSLKS-HTRPIERLS-TDSMGVLKIWELHHELAIYDLASADNSILIPHPTQTRALLTTTTELIRIFNV-EGHTNEITSLILSASLDGTIRRWNWLTEE--EERELEE Stehi1 GDPINLQGVVWVAENTTVARKIDLESGKSIRVFRGHSAPVSCLTLLITGSWDQ--HIKLWDAETANVISSAHTDFVKVLLVILVSGSSDKTVRIWDLSLGSISA-HTRPVEALT-ADTMGAIKVWELYHRTRVNQLASTDETVQITHSAAFRALIAASGDNIRTYDI-EGHWHDVTGLIVSASVDLTIRRWRLLTEE--EERELAE Tapde11 GSPLQFQTKVFIAESGSVARRVHVETGATSAVYRGHIAPVTKVV-IATSSWDK--TIRIFHKRTRETLKIAHTDFVKCLL-LLLSGSSDSHIRAWSLSVYALKG-HARGVESMS-GGSESSIRRWNILHDTSVYSLASADKTSRFDHPDYVRDLITACREDIRIFDL-QGHFSEVSSLLISVSLDATLRKWNLLTAE--EAAELEE Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 GNPFRISSKAWVAESGWQIRRVDLNSFTTKKLYKGHSGPVTSVVLVLSGSWDK--TIRIWDIKTAQVLHIGHTDFVKSLLILLLSTSSDRSLRLWDLSIQTIRE-HTRPVESST-SDSLGVMKEWELGHETSVGFIASMDKSIMITHTGYVKSLLTAGDEDLHVFPV-PGHCAEVSVLILSGSLDGTIRNWSI------------- Trire2 GDPIAMKSKIFIAESAGFVRRIDLSSGSTKTTYRGPKAPVTCVAVVFAGCWDK--DIWSWDVETAQPGRKGHADFVKVVLCILISGGADKKILVWDIELHTLQD-PTTAVQHIS-ASSDPHIRRWKIEHDTSVYKLASADGTAKYVHGDYVRAVITAGRENVKVWDL-EGHYEEVTDLVCSVSIDGTIRTWPLLTAE--EEAELAE Umbra1 GNAVKTPSKCYIAESAFTARKINLETGNAVKIFKGHDGPATSIALLFTGSWDK--TVKQWDVKTGECVKTGHTDFVKSILLFLFSGSADAHIRQWDITVRDLKG-HTRSVECLS-ASSDRTIRKWNVGHETNVFALGTAF------------------------------------------------------------------ Ustma22 GYPIHLHPNIWTSEAGGVVRQIDAESGVTVAVYKGAKAPVPSFDFLVTGSWDK--AIRVYRTRSPAPLLTAMSDFVKCVHVYIATAGSDKSIMIWDASVHQCKV-HLRPVNALS-ADSMGRILESTLGFSTAVYDLASGDKSAAIAHDDFVKAVVTGGSEHVRMFVV-EAHWHEVSALIVSASLDGSVRRFALMTPD--EEAELAE Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3411.fasta_al_trimmed; alignment length = 79] Allma1 ------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------- Aspfu1 ------------------------------------------------------------------------------- Aurde31 FSPLQRERYESYRRSYFNKQAVRRLHQSL-GLTVSPQVAQVVAGFSKVFVGEIIEKARQVQGPLSPDHLREAYRLYQDE Batde5 FNPEQLQRYEVYRRAHLPKSSMRKYQNIV-GGIVPASVGIIVGGCGKLFVGEIVEEALNYMIPIRPDHLREAFRRYRLQ Botbo1 FSDDQHKRYEWYRRAALNKGNIRKVNQTL-NHSVSPNVAQVIAGVAKVFVGEIVEKARKVQGPLAPEHLREAYRLYQEE Botci1 ------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------- Canalb1 FTDDQMERFEAYRRMTVNKPGVKKINGIV-GHTIPQIIAVVMAGVSKSFLGEIISKAFEIQHPLQPEHIREAWRLYQLE Cangl ------------------------------------------------------------------------------- Capow FTPEQLHRYECYRRSGFPRAVIRKVQQQL-NSAVSIPSVIVMAGIAKVFVGEIIEQARDVMDKIQPAHIREALRRLRSK Catan2 ------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------- Coere1 MTDEQRQRYGVYRRAALNKSAVKKLSQVL-NQQITSTLTFVIAGFSKVFIGEIVERAVQLQGPLTPEHLREAYRLYLKE Conco1 FSPDQHRRFEVFRRTALPKNTVKRLQNIL-NQQVSPTLAFVVAGYSKVFIGEITELALDIQGPLSPEHIREAYRRY--- Conpu1 FSPAQYDRFEAYRRHALPKQAVRKVQQTT-GQQVSQPVAQIVAGFGKVFVGEIVEKAREVQGPLTPDHLREAYRMYQEE Copci FTPEQYDRFEAYRRHLLPKQAVRKVQQTL-GQQVSQPVAQIIAGFSKVFVGEMVEKARQVQGPLSPDHLREAYRMYQEE Croqu1 FDPQQMDRYTEYRTSGLAKTNVRKLNSVL-QQSVSERVTIVIRGLAKVFVGEMVEQALEVQGPITPFDLREAYRAHLAE CryneH991 MDEEQARRFDTFSTVAINKNAIKRLRDLF-DQHCPPQLSQVVAGMAKVFVADVIEMAKDLQGPLQPYHLKLARMCLEEQ Crypa2 ------------------------------------------------------------------------------- Debha1 FTDDQMERFESYRRMTVNKPGVKKINGVL-GHSIPQNIAVVLAGLSKLFLGEIITRAFEIQKPLLPEHIREAWRLYKLE Dekbr2 MDKEQMSRYEFFRRTNLNTGSVRRLSSTI-GQSISTCLSKIIGGVGKMFVGNIVERAKDAQTHLTADHIRVAYKLYGQE Dicdi FSEDQQTRFEYYKRSSFQRANIKKVQSVL-SAPVNQTSAIVMGGIAKVFVGEIVELARSIMGPIRPRHIREAYRRLKES Dmel FTEEQLDRYEMYRRSAFPKAAVKRLQTIT-GCSVSQNVVIAMSGIAKVFVGEVVEEALDVMGALQPKFIREAVRRLRTK Enthi LKKVYMDSYEI----CFDSKNVASVESVDENLHISKSTQHVMGAICKVFLAELVSETQKVRGPLLPQEVAAAYRRLIER Falba ------------------------------------------------------------------------------- Fomme1 FSADQYDRYEAYRRNALPKQAVRRVQQSL-GQQVSAPVAQIVAGFGKVFVGEIIEKARKVQGPLSPDHLREAYRQYQQE Fusgr1 ------------------------------------------------------------------------------- Galma1 LSPAQYDRFEAYRRHALPKQAVRKVQQTL-GQQVSQPVAQIIAGFSKVFVGEIVEKARAVQGPLSPDHLREAYRAYQEE Ganpr1 MTEDEWKRMETYRRTKIPDGIIKKISNST-GQTATKNVIIAISSAAKVFVGDIVDRAKEVQGALRPDHLREAYRRYRKD Gloin1 FSEEQLKRYEVYRRSALSKPNVKRMGQIL-GHPCSHNMSIVVAGFAKVFVGEIVEKALDVRGSLSPEHLREAYRRYKKE Hisca1 ------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------- Lacbi2 FSPSQYDRFESYRRHALPKQAVRKVQQTL-GYQASQPVAQIIAGFSKVFVGEIVEQAREIQGPLSPDHLREAYRAYQQE Lenti61 FSPEQYDRFEAYRRHALPKQAVRKVQQAT-GQQVSQPVAQIVAGFSKVFVGEIVEKARSVQGPLSPDHLREAYRMYQEE Malgl1 MDDDQLERHMASRRGTLNKGGVRKVMSLF------------------------VQCS---------------------- Mellp23 FDPQQMDRYTEYRNSGLAKGSVRKLNSVL-QQSVSERITIVVRGFAKVFVGEMVEKALEVQGPITPFDLREAYRAHLSE Mnele ------------------------------------------------------------------------------- Monbr FTPEQHERHAIYRRSKFKPNNIRKV--------------------------------------IAPKH----HRPIQSK Morel2 FSDEQLQRYEVYRRSVLGRSTVKKLGTIL-NQQVTQTMAFVVAGFCKVFVGEMVEKAREVMGPIRPEHLREAQRRYKKE Mucci2 FSDDQLQRYEGYRRSALNRTNVKRLSQVL-NQQCSQTMAFVVAGFSKVYVGEIVEKAKEIMGAIRPEHLREAHRRYKRD Mydma FSEEQLNRYEMYRRASFPKAAIKRFQNVTGGTSVPPNVVIAMAGIAKVFVGEIVEEALDVMGPIKPKHLREASRILKKK Neucr2 ------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------- Phybl2 FTGDQLHRYEGYRRSALNRTNVKRLSQVL-NQQCSQTMAFVVAGFSKVYVGEIIEKAREVMGAIRPEHLREAHRRYKKE Picst3 FTDEQMERFEAYRRMTVNKPGIKKINGVL-GHSIPQNIAVVLAGISKLFLGEIISKAFEMQKPLQPNYIREAWRLYKLE Plicr1 FSPAQYDRFEAYRRHALPKQAVRKVQQNL-GQQISQPVAQIVAGFAKVFVGEIIEKARADQGPLSPDNLRQAYRAYQQE Polpo FTEEQQTRYEFYRRSSLNRANVKKVQGVI-TTPVNQTSAIIMAGISKVFVGEIVETARSIMGPLRPRHIREAYRRLKET Pucgr2 FDAQQMDRYSEYRNSGLAKANVRKLNTIL-QQSVTDRVTIVIRGFAKVFVGHMVEQALEVQGPITQYDLKEAYRAYLSE Punst1 LSPEQYDRFEAYRRHALPKQAVRKVQQAL-GQQVSQPVAQIVAGFSKVFVGEIIEKARRVQGPLTPDHLREAYRMYQAE Rhior3 ------------------------------------------------------------------------------- Rhoto1 FDEQQMDRYEAYRRSGLTKSSVRKLNQVL-QQSVSPSILTVVRGFAKVFVGEIVEKARSVSGPLTPRDLREAYRLYLEE Rozal11 MDDDQMKRYEVYRRSGFPKAAIRKFQGTL-NQSANENTIVVLRGIAKVFVGEVIEEAKNVQGALTPSQIREAYRRLKKK Sacce1 ------------------------------------------------------------------------------- Salro FTEEQRIRHESYRRSRFDPKVLRKVQSLASTAEKRRTVLTVLGALAKVHVGEIVETALDVQGPLTPAHVREARRRIKET Schco3 FSPEQYDRFEAYRRHALPKQAVRKVQQTV-GQQVSQPVAQIVAGFAKVFVGEIVEKARAVQGPLTPDHMREAYRMYQQE Schpo1 FDEEQMQRYEVFRRANLNKTNVKKLNQIL-NQSVTPNVAIVISGFSKVFVGEIVELARKIQGPLSPDHLREAYRLSRQ- Sorma ------------------------------------------------------------------------------- Sphar FSEEQMSRYESYRRAGFPRAAMKRVQQIT-GSIVPPTAVIVMSGITKIFCGEVVESSIKVQGALRPKHIREGLRRLRNN Spipu1 FTQEQVQRYEVFRRAHFQKGGMKKFQGVL-GQNVSESSAIVVAGAAKLFVGEMTEKAREVMGGIQPEHLREAYRRYKHD Sporo1 ------------------------------------------------------------------------------- Stehi1 FTPEQYERFEAYRRHALPKQAVRKVQQTL-GQQVSMPVAQVVAGFSKVFVGEIVEKAREVQGPLSPDHLREAYRSYQQE Tapde11 FNQGQMARYEVFRRVKLNTLSVKRLNAIL-SQTLPQNIAVVIAGSGKVFVSEIVERARHVQGPLTPEHLREAYRQYKVE Thetr ------------------------------------------------------------------------------- Treme1 MDSDQAKRYDTFYSVILPKQAVSRLREFF-DQHIKPSLSQIVAGLGKIYLAEIIELGRFLQGALKPEHLRIAKERWEDT Trire2 ------------------------------------------------------------------------------- Umbra1 FSDEQMARFEAWSRSGFNKNNVRKLSQVL-NQPCSPTMALAVAGFAKVFVGEIIEKAREVMGPMRPDHIREAYRQYKKE Ustma22 MDEDQLDRHMASRRGALNKTNVRKLNHVL-SQSVSQHVAMVVSGVAKIFVGEIIETAREIQGPLRPNHLREAHRQYYLK Walse1 FSSEQLQRYEVYRRAALNKNTIRKLNQTL-NQSVSQNVSIIVSGFSKVFVGEIVEKAREVQGPLSADQIREAHRLYQKD Zygro1 ------------------------------------------------------------------------------- [Cluster3415.fasta_al_trimmed; alignment length = 87] Allma1 --------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------- Aspfu1 AARFTAPYQ-NPPVKRAFRGDW-WDKQERRNFGE-PVHEENEILGVFSPEGLFQIGAFIATFLTLPDKPSVPQT--YP-GGLEKELG Aurde31 RARGLQSYP-NLPVYSYQRGPW-WDRQNRRHFGE-PIPAEDEALSVWSPDALFHFSIAVVCFLGYVEAPVARRS--YPHDGLVKELG Batde5 --------------------------------------------------------------------------------------- Botbo1 AARSYATYP-QLPESPQRRKGW-WDIQDRRNFGE-TVHEQAEALSMWSPDAAFQIGVAILGFVAFPDRPAVPRS--YPRDGLVEELG Botci1 PRQTTLIYI-NPPVKRQFRADW-WDKQERRNYGE-PVHEDNDILGIFSPEAGFQFGLFILSVLGLPDKQSAPRE--FE-GGLERELG Caeel --------------------------------------------------------------------------------------- Canalb1 LTRSYATFK-NPPVLKQYLAKY-DDPQNRRNKND-PMHIDEDMLDLWSPDALKHNAIFFGLIFGIPEKPAMIRS--FPYNGLADALG Cangl --------------------------------------------------------------------------------------- Capow LRRFAATYP-DFASSAQLKSLY-EDAQERRNLKD-TLHENDELYTVWVVDALKHLLIMAGLLTGLSRKPTTQRE--LPFH------- Catan2 --------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------- CocheC53 QIRTALTYI-NPPEKRGNRGDY-WDKQERRNYGE-PCHEDNDILGVLALHGFVLMGTFIATVFGLPDKISAPKT--YP-DGLEAELG Coere1 SMRTIAAYP-NLPVFSEERRGW-WDRQNRRNFGE-TIPEQYEILNMLAPTQVSKMWAFIITIGSVPERPYMRAY--YP-NGLKEELG Conco1 SLRMVQTYP-NLPIYAQHKWHY-QDQQDRRNLED-PINEQDEVLSVWAPDALFELLC-VAGFVASPECPAVRRS--YPFDGLRAELG Conpu1 SSRAFHEYP-DLPVSNQQRYGW-WDPQMRRNFNE-PASPSPQLLSMWGPDALRQFLLAAGSFVSFPDRPAVPRE--YPYSGLVTELG Copci RARSRSNYP-QLPVPKGSLRGW-DDMLERRNFGE-PLHEQEEVLSMWGPDALRHFLFAVTAFIGAPDAPAIKRE--YPYNGLIKELG Croqu1 QSRFYSTYP-RVETSRQWRAKW-DDPQERCNFNE-PLHAEEEMMGIWAPDALLNLAVAFSALGGIPKSPVVPRE--FPYDGLSRELG CryneH991 ASRLASSYP-QLPESLQNRFGW-WDIQERKNFGE-VVHESEDVLGMWGPDALLQLCTAFGLVGAVPERPAIARD--YPYGGLEKELG Crypa2 QQRTFLPYV-QPPIKRQFRGDW-WDKQERRNFGE-PVHEDYDQLGMFTPYGFFQVGVFIAAFLSLPDRVSFPRD--FD-GGLERELG Debha1 SVRFLTTYD-NVKVLAQDKVKY-DDQQNRRNIND-PLNIEEDYYDIWSPDALKHNGIFFSLIIGFPAKPAMPRS--YPFGGLAKELG Dekbr2 ITKRFVSFGVDVPIPPQYRKKY-DDQQNRVNFGE-KIHPFHDYMDMWAPDALGQLLTFFGILGAFPDRPAMPRD--YPYNGLYKDLG Dicdi --------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------- Fomme1 --REYATYP-QLPISRGTLLGW-WDNQMRRNFGD-IPHEKDEMYSMWGPDALFRFGLGVAMFGGIPELKAVRRQ--YPFDGLVKELG Fusgr1 QRRTFLPYI-NPPIKRQFRGNW-WDPQERRNFGE-PIHEDNDVLGIFSPWGAVMVGTFIAVFMSVPDRPAYPRA--FE-GGLERELG Galma1 TRRYASTYP-QLPVSRQELLGW-DDPLTRRNFGD-TLHEHEEALSMWGPDALRQFLYAVAGFVTFPEPPAVRRQ--YPFDGLVKELG Ganpr1 --------------------------------------------------------------------------------------- Gloin1 IRRNYLPYP-NLPESRLNRLGW-EDQQNRVNLNE-TLHEEEEALSVWSFDALKSLGIFFGSVGLFPEAPMEKKT--YPYEGLRVELG Hisca1 --------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------- Lacbi2 FARAYATYP-QLPISRQYLRPW-QDPLMRRNFGD-TLPEQEEVLSMWGPDALRQLLLAFAGFATFPDAPAIRRE--YPYSGLVQELG Lenti61 AATQAPAYP-RLPVSKQTRLGW-EDLQFRRNYGE-PLHEQEEMLSMWGPDAIRWFSIAVLGFVGLPTIPAVRRE--YPFAGLASELG Malgl1 VVRMQDVYP-AMPQNQQFRRHW-WDTQDRRQYGE-TLHEQDDVLNMWSPDALRHFLAAVGVISLFFQPPMMRKT--FPRDGLAAELG Mellp23 -------YP-RIEASRQWRAKW-DDPQERCNLNE-PLHAEEEMMGIWAPDALLNLAIAFSTLGGIPKSPVVPRE--FPYNGLTQELG Mnele EERQFGSYP-RMPYHRQLKVKY--DYGMRKNFGE-TFHILEEWLTPQGTEGTLDLILVIGSVWFLMYAPKV-----YPFDNLWVETG Monbr AVRSM--YP-DFKVNAQTKWGF-WDKQDRRNFNE-TLHEDDEIHSVWSPDALLQLLMLLAVLAGVEKRPVENREKLIP--------- Morel2 SASSLHNYP-NLPYNQQWRAGY-WDRQDRRNFGE-TVPEEDEVLNIWSPDGVKRLLAAAAAFIGFPEPHFTRRN--YPHDGLLEALG Mucci2 AVRPQSTYP-NLPISAQTRFGW-DDPQDKRNFGE-AIHEEDEIMGVWAPDAASQFALFAAVFAGVPDKVAVPRT--YPYNGLTEEFG Mydma TVRYYSAYP-NYKFSYQLRKKY-WDQQDRRDFGE-PLHIEHDILSVWMPDGEMFFHLALGVLLWFSRDTAVPKP--YPYNNLYLEMG Neucr2 QRRTFLPYI-NPPIKRQFRAKW-WDPQERRNFGE-PVHEDHDLLGMFSPYGLAQIGAFIVAFLGLPDKVSYPRE--FE-DGLLQELG Orpsp11 --------------------------------------------------------------------------------------- Pench1 AARAISPYP-NPPVKRAHRGGW-WDAQEKRNFGE-PVHEDNEILGVFSPEGFFHLGCFVAAFLGLPDKPSVPKA--YA-DGLETELG Phybl2 -VRAQSTYP-NLPNSSQARFGW-WDPQDKRNFGE-NVHEEDEIMGVWAPDALAQIGVFFASMAAFPERPVIQRT--YPFGGLTEELG Picst3 AFRSLTTYP-DFTQLAQDKAKY-DDPQNRRNLND-PVSINDDLYDIWSPDALKHNAIFFSLVFGFPEKPAMPRS--FPFGGLAKELG Plicr1 NTRSYATYP-ELPVSRQYLKGW-WDPQMRRNFGE-LLHEKEELYSMWGPDALYQFTLVTLGFVSFPERPAVPRE--YPFSGLVTELG Polpo --------------------------------------------------------------------------------------- Pucgr2 SRRAYASYP-RVELSRQWRAKW-DDPQERCNFNE-PLHAEEEMMGIWAPDALINLAVAFTGLGVIPSSPVVPRT--FPFDGLTRELG Punst1 AARTYATYD-NPPISRQRLKGWNWDPQMRRNFGD-PLHEQEELLSMVGPDALRWFTIATLSFVTFPDLPAVRRE--YPFDGLVTELG Rhior3 SVRPQSTYP-NLPNSTQARYGW-WDPQDKRNFGE-TLHEEDEIMGVWAPDALAQLALFAGAIASVPESPAVKRT--YPYNGLTEEFG Rhoto1 -SRSYATYP-KMYESRQLRQYW-DK-QERVNFGE-PVPLNDDLQSMWAPDALLQLGMAFSLIGLFPDAPALPRA--YPYDGLVKELS Rozal11 --------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------- Salro AVRSVHTYP-EVVKSAQLKFGY-WNSQDRRNFND-PLDEDDDIKTMWVVDALLQLLGVFGLLTAVDKKPVKSRE--FP--------- Schco3 VVRNYGDTP-PLPLNKQYRKGW-DDPQMRRNFGD-PMHEQEELVSMWGPDALRHFTIAFSIFAGIPQIPAIRRE--YPHDGLKNAFG Schpo1 --------------------------------------------------------------------------------------- Sorma QRRTFLPYI-NPPIKRQHRAEW-WDPQERRNFGE-PVHEDHDILGMFSPYGLAQIGAFIVAFLGLPDKVSYPRE--FE-GGLLKELG Sphar --------------------------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------------------------- Sporo1 --------------------------------------------------------------------------------------- Stehi1 ATRSPATYP-QLPVSRQSLTGW-WDVAARRNMGD-TLHEQEELYSMQGPDAARHFAVACGVFFSIPERPSVPRE--YPYEGLVKELG Tapde11 TVRSSSQYPTNVPINRQTKEKY-DDQQSRRNFGE-TLHEEDDVLTVFSPDAFLHIGIFITAVFGITPLQAVRRT--YPYDGTTAPSH Thetr GLRAAAG---AMP------TAYTWDQRERLRVEEGRLHEEADVLD--EPIALGALGLAFVGIGAFQSNPAVPRE--FPFNGLHVELG Treme1 AARRCASYP-QLPVSLQSRFGW-WDQQERKNFGE-VVHEEEDRLGMWGPDALMQVSSAFSLIGLFPQRPVAQRT--YPYGGLAVELG Trire2 QRRGFLPYI-NPPIKRQFRATW-WDPQERRNFGE-PVHEDNDVLGIFSPWGLIMVGSFIAVFLGVPDRVAYPRE--FE-NGLERELG Umbra1 ASRNQSTYP-NLPLSNQIRFGW-DDNQDRRNFGE-PLNEQDEVLGVWAPDALAQFGAFIGVISAFPEKTAIPRT--YPYGGLKQELG Ustma22 --RTTSTYP-DLPVSQQQR-KW-WDPQEKRNFGE-TPHEQDDVLSVWAPDALRQFLVAIGVVVLFPEKPALPRT--YPRDGLATELG Walse1 SVRTYATYP-QFVQKAIERNKY-WDQQGRANFGD-TLHEDEDVLGIHAPDSAKSILYTALAFAAFPERNVAPRD--YPRDGLKEELS Zygro1 --------------------------------------------------------------------------------------- [Cluster3416.fasta_al_trimmed; alignment length = 58] Allma1 MS--AAAKVTLAGSILFTIASVSAVHWQHIKERERMHEGVLR-DERLAAKAAQQALER Ashgo11 MS--RASKITLALCTAASAATVVTVHLVQEMERDALKQGPIK-DLRTAEKELQLELRR Aspfu1 MS--RASKVTLALTSLGTAGIVYFVHWSQEQEKAQMHKGVER-DEKQRIREMQKALEE Aurde31 MT--RAAKVTLAASIVLTTAVVYGVHWLQDREQRAMYMGVVR-DERRRQKEESQKKRA Batde5 MS--RNSKLTFAASCLFATVCVFGVHYMQELDVKTRRVGILR-DVRRSDKMKQEELRK Botbo1 MS--RAARATLTASLVFAAVTVWGVHYIQTKEREIMYQGVVR-DARQAAKAESLKKRE Botci1 MS--RAAKLTLFGTSLFAASTIVFVHYAQTAEKAAMHAGVIR-DEQQRIKDLQRAMEE Caeel ---------------------------------------------------------- Canalb1 MS--TASKITLGASCAFAVGAFVFINYSQQAERQALRQGPIK-DARQQAKKEQTELRE Cangl MS--RASKITFGVSCAVTLATIIGVHYVQELERETLHQGPIK-DKRVAEKELQQELRK Capow MS--FAAKSFLAVSTAATVGIIYYVHSNQQSDRERLRMGIER-DERQQRKEQEQQNER Catan2 MS--AASKVTLMGSILFTVASVTAVHWQQNKERERMHQGVIR-DARLAAKEAQQQLER Cioin MS--STARMAFGGSIIFTTSMIAYVHWNQQASQEQMREGVRR-DEEKERKEEEQRL-- CocheC53 MS--RASQITLATTCVTAVGIVAFVHWSQKADKAAMHMGVVR-DEQQRIKEMQRELEQ Coere1 MS--RAAKLTFMGSCVFAASTIWFVHRAQKMERESMYQGVLR-DERKAQREETRARYA Conco1 ---------------------------------------------------------- Conpu1 ---------------------------------------------------------- Copci MANLRKAKITLGGAVAFCALTIWAVHYQQEKERDTMYQGVIR-DERRREKEESQRKRE Croqu1 MS--RLAKLTFAGTSVLTGLTVWGVHLMQLSERDAMYQGVLR-DERVRKRNEQRRRQV CryneH991 ---------------------------------------------------------- Crypa2 AS--RGSKIALAGTSLFAVTTIVFVHFQQKAEKSAMHQGVVR-DEQQRVKELQKQLEA Debha1 MS--TASKITFGSACLLAGGTFLGINYLQRSERASLRQGPIK-DERVAAKKEQMMLKE Dekbr2 ---------------------------------------------------------- Dicdi ---------------------------------------------------------- Dmel MS--TASRVTLGLAVSISTAIIGYVHYKQSADRLRLHDGVLR-DQQQRRKTKQLKARE Enthi ---------------------------------------------------------- Falba ---------------------------------------------------------- Fomme1 MS--RAARITLAVSALFAVGTIVGVHYMQQAEHETMYKGVIR-DARRQEKRESQRKRE Fusgr1 ---------------------------------------------------------- Galma1 MAD-RRAKATLFGAVLFSSVTIWAVHFQQHQERDTMYKGVLK-DERRRQKRISQQKRE Ganpr1 MS--RTAKVTFGASVAWLGVCVVGVHLMKEWEHKAMRANIVKFDEREARRDEMTRKRE Gloin1 MS--RTAKITLIAAIFISTGTVWGVHHLQKKEKEFMHAGILR-DERRAKKEQQLILQR Hisca1 MS--RASKLTLVGTSLMTAGIVYFVHWTQEADKAAMHAGVQR-DENQRIKEMQRALEA Klula1 MS--RASKITLGLTTLFTATIVVGVHHVQELERQTLHQGPIK-DQRVAEKEYQLELRK Lacbi2 MSE-KRAIATLTGAVFLSALTIWAVHFQQHQERETMYKGVLR-DQRRQEKANSQRKRE Lenti61 MS--RAAKITLGAAIMGSALIIWGVHHLQLTERETMYQGVIR-DERRREKQRSLEKRE Malgl1 ---------------------------------------------------------- Mellp23 MS--RLAKFTLVGTAAITGMTVWGVHFLQLSEREAMYQGVLR-DERVRKREDQQRKQA Mnele ---------------------------------------------------------- Monbr ---------------------------------------------------------- Morel2 MS--TKAKMTLGITTLLTVATVYGVHYQQMSEKETMRLGIVK-DERVAKKAVQQELQR Mucci2 MS--KAAKATLTASIVFCCASVFGVHYIQNEEKENLRAGVLR-DERRKKKKEQQELHE Mydma ---------------------------------------------------------- Neucr2 MS--RASKLTLLGTSAFALGTVALVHWQQQAEKEAMHAGVIR-DEQQRIKEMQRELEN Orpsp11 ---------------------------------------------------------- Pench1 ------------------MGIVWFVHWAQEADRAAMHKGVER-DEKQRVREMQKALEQ Phybl2 MS--TPAKITLGASVAFCCATVWGVHYLQTYEKELLRKGLEK-EERRDKKEEQRALHE Picst3 MS--TASKITFGLSCVSAVGAFVFINYSQKLERLALRQGPIK-DARVQAKKEQMELRE Plicr1 MS--RAAKATLVGAIALSTFTVWFVHFQQNQEHENMYKGVLR-DERRLEKKESLRKRE Polpo ---------------------------------------------------------- Pucgr2 MS--RTAKLTLLLTSSITGLTVWGVHFLQTSERDAMYQGVIR-DERIKVREEQKVRRE Punst1 MS--RRAQATLLGAVLFSTLTIWGVHYMQDQERETMYQGVLR-DERRLQKEESQRKRE Rhior3 MS--TKAKLTLASSVAFCIASVTGVHYIQNSEKENLRAGVLQ-DERRRKKQEQTELHE Rhoto1 MS--RTAKALFAGSVLFCGASIWGVHMIQVRERETMFAGVIR-DERLAAKEDQARKRA Rozal11 ---------------------------------------------------------- Sacce1 MS--RASKITFAASCLITAATVVGVHYVQEMERETLHQGPIK-DKRVEEKEEQKELRK Salro KR--RRAWWALAASIVFSTGMIAFVHLNQNKEREALHEGVIK-DERQERKEQEQQMEL Schco3 MST-RKAALTLGTVVCLSALTVWGVHYQQEAERESMYQGVLR-DVRRREKEESKKKRE Schpo1 MS--TASKLCIVGAGVFSVYMVYFVHNNQIIEREKMSAGVQK-DERKRIKKRQQELRK Sorma MS--RASKLTLLGTSAFALGTVFFVHWQQKSEKEAMHAGVIR-DEQQRIKDMQRELEA Sphar ---------------------------------------------------------- Spipu1 ---------------------------------------------------------- Sporo1 ---------------------------------------------------------- Stehi1 MS--RAAKATLAASIVATTFTVWFVHYQQQQEHETMYKGVLR-DERRKEKEESQRKRA Tapde11 ---------------------------------------------------------- Thetr ---------------------------------------------------------- Treme1 ---------------------------------------------------------- Trire2 MS--SASKISLAATSLFTAGVIVFVHFQQKADQAAMHAGVVR-DEQQRVKDMQRALEE Umbra1 MS--TRAKITLAGSFAFCGLTIWGVHYLQRYEKELMRAGLVR-EERQQRKDAQKALHE Ustma22 MS--RPAKFTLAASVLVSGLTVWGVHYMQEREREVMYRGVER-DARQEEKQINQEKEA Walse1 ---------------------------------------------------------- Zygro1 MS--RASKITFTLSCILTATTVVGVHVVQGMERETLHQGPIK-DKRVAAKEEQLELRR [Cluster3420.fasta_al_trimmed; alignment length = 149] Allma1 AMQLYQQGMDLEHEGNLAGALKAYRAAFKIDISVLPAELLARAFKFAA-LSLVCKKTIWKHLCDWLQYFIREPRIRFDGVYISRCMYVRQGI-SNNP--VHLVEYFRYLRFFRDGRVLSYMTTSE--PRDIVKQFKTVQIKGSGKHNRL Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ALEHFERAVEKEAQGNLGDSLHHYRKAYRLDIANIPTEVLLVILRHVR-MALVCKRHIWKRLCSWSQVFQMFPRIRFTGVYLSTVNYTRPGAASDSP--IHIVTYYRYLRFYSDGSVISILTTAE--PLDVVPYIMHLSLRSSSKNTKL Aurde31 ALDYYRLAVDYEQRGELDHALALYRKAFRLDIARMPDELLVQVLVLLR-MSLVNRKTIWRTLVDFRRMWIECPRVRLDGVYISVCHYMRNGV-SHHP--QHLITYHRYLRFFPDGTMLMLLSNGDSPPREIVYTLMTLVLKSRGRWAKL Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 AVAVYGRAVEAEQRGRLDEALDLYRKSFRMDFARLPDEIVVLVLRQFR-FGTINKKSLWRDLVDYRRFFMEHPRVRMDGVYIAVCHYVRQGL-GINV--THLVTYHRYLRFLPNGTVLSLLLNDDHAPSDVVHQLMTLHLRSKGRWNKL Botci1 ALEHYEKAVEREGQGSLGDSLDLYRKAFRLDIADVPDEILIQIFKEVR-ITQVCKRQIWKRICSWKQMFRLRPRIRFNGCYISTVNYIRPGQASNSP--VHIVTYYRYLRFYRDGTLISLLTTTE--PSEVVHHLVLMASRLSAKSVKM Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 AISLFEQAIKKESQGLMSDAVDLYRKSFKINLVHLPNDIWTYILEILK-MSTTCKKTIWREICSWKFMLHNRPFIKFLGCYISVVNYYSEGGKASNP--VKTITYYRYLRFYRDGTVVKVLSVLP--PDQVVPYLYWFQIKSLNKHAKL Cangl ALQLWEQGAAKEQAGSLMDAINFYRKALKVHLEMLPDDILLQIIKQVN-LSKTCASLPYQAFADAKQMICNRPFIKYHGIYISVVNVVRYGANDMNP--IHILTYYRYFRFYPDGSCLRLLTTDE--PSFVVKHFEKFVIKNQKKHHQL Capow ----------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 AMDLYEEAMELEVSGRLADALQSYRAAFKLDISRLPDDLLLRVFQVAA-TSLVCKQTVWRYVCDWMDFFRSEPRLRTDGAYISACRYIRPGF-SNAP--ILIVEYYRYLRFFRNGTVIAFMSPSE--PRDVVKHLIQLEIRGNNRVARL Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ALEHYEKAVEKESQGNLGESVDLYRKAFKLDIASTPEEIVVEILEQLR-LSQVCKRRVWKRLASYRTLFRQRPRIRFNGCYISTVNYARPGQAQNSP--IHIVTYFRYLRFLRDGTCISLLTTSE--PPDVVPYLMALTVGSAAKINRL Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ALETYKLAVQKEKEGDLGQALLHYRRAFKLDLNILPKEAIVKVLQCLR-FSLTCKRSLWQHLVVYQYFWTEYPKIRYDGIYISTCSYIRQGS-SNNP--VHLVTYYRYIRFYPDGTLIKLLTPDE--PVNVVKLLALLNLKSTGLFNKL Conpu1 AIEVYRNAVRHEQQSNLDEALRLYRNAFRLDIGLLPNELLLHILRTLR-FASVNRKSIWREFVDYRRVYMEQPRVRMDGVYIAVCHYVRRGL-SVNI--DHLITYHRYLRFFPDGTVLSLLANEEMQPATVIPMLMELELRSRGRWNRL Copci ALQVYKQAVQHEQRQDLDTALILYRQAFRLDLNILPPEMLFAILRNLR-FATVSRKVYWSDLVDFRRVYIEHPRIRMDGVYIATCHYVRAGI-SMSR--SHLITYHRYLRFYPNGQVLSLLANEQLSPQDVIPMLMTLEVRSKGRWNRL Croqu1 ----------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 AVQTYAKAVESEQSGQLNEALILYRRAFKMDIASLPAELIDPILAHLR-FAATCWRNVWRRLAEWRTTLIEEERVRMDGCYIAVCHYIRPG--AIAI--THLITYHRFLRFYPDGSVISFLTTDH--PSEIVPVLMELALRQTGRWNKL Crypa2 ALDHYERAVEKETQGSLGDSLTLYRKAFRMDIASLPEEILVHILRDVR-LSRVCKRSVWRHICSWQKMFRRRPRIRFNGCYISTVNYIRPGQ-QNSP--VHIVTYYRYLRLFRDGTAISLCTVDE--PSAVVHHMMELSLRSAARNNKL Debha1 AIALFEKGIEKESHGSMSDAVEFYRKAFRINLMHLPNDIWMHIFEILN-FSITCKKNIWRKLCSWKYMLRNRPFIKFHGCYISVINYYSEGGKASNP--VKTITYYRYLRFYPDGTCVKVLSTLE--PNRVIPNLYHFQIKSLFKHSKL Dekbr2 AISLFEVAAAKEHVGLLSEAAEYYRKAYKLDIAILPDEMLMYILKLLN-LSMTCKKRTWKVMAQYLKMLRERPFIKYRGVYVSTVITQKPGGREAVP--FRMITYYRYYRFFQDGSSLKLLTILE--PSKVIPLLDRLQIENGSRHDRL Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 AVATYRLAVLREQAGVLDEALRLYRNAFRLDLRRVPDEVIVLILMTMR-FAMLDRKAIWRFLVDYRRLFIEHPRLRLDGVYIAVCHYVRPGVNSVNV--SHLITYHRYLRFLADGTVISLLANEDVEPQTIVPLLMTLHLRSRGRWNRL Fusgr1 ALDHFEEAMHKEDQGNMGDSLKLYRKAYRLDLADLPDEILIHILRDIR-LSRVCKRRIWRRVATWKNLFRSRPRIRFNGCYISTVNYVRTGQASGSP--IHIVTYYRYLRFFRDGTLISLLTTNE--PADVVHHLMDLSLRSAARNNKL Galma1 ALNVYGRAIEHEQRSELDQALLLYRQAFRLDLNVLPEELLVVVLGKLR-FARVSKKGIWRKLVDFRRVYIEHPRLRLDGVYIATCHYVRPGL-SVNT--SHLITYHRYLRFYPNGQVLSLLANEEHTPQQIIPVLMTLNLRSRGRWNRM Ganpr1 ALRLYDLASTAERQGNLSKALEFYQSAHKLELTKLPGEVLLALLRAVN-ASEVCRRGVWRDLCDWRRMLIHKPRLRLDGVYISRCNYWRQGH--YTP--YILVSYFRFLRFFKDGSVVSVCTSLE--PVEVVKLLMRLAVNSVGSHNAL Gloin1 ALEIYVKAVTKEREGNLSEALKYYRQALKLDIAKLPNELIVCILHQLR-FALTCKKSLWRYLCDWKRMYIERPRIRLDGVFISTCNYLRPGS-ANQP--IHLVTYYRYIRFYSDGTCVALLTTNE--PINVVKNFLIFDLKSTGRHNKL Hisca1 ALEHFEAATRKEAQGNLGSSLDLYRKAYRLDISRVPSEVLVEILWHVR-LSSVCKRHIWRRLCSWSQVFQAFPRIRFTGIYISTVNYTRPGANSNTP--IHIVTYYRYLRFYPDGSVISLLTTTE--PVDVVRYIMHLALRSASKNTKL Klula1 AIALWELGYSKETAGAMTDAIKYYRKALRMNLDMLPDDILSMIIDMVN-LSLTCKKSPYRTFANYRKMLKERPYIKFHGIYISVVNYLRHGSIPLNP--IHMITYYRYFRFYPDGRCIRLLTTDE--PNIVVPGFEILKISNRKKFSKL Lacbi2 ALDLYRRAVQHEQRGELDDALRSYRQAFHLDLNRLPDELLVLIIRNLR-FAAVNRKVIWREFIDYRRVYIEHPRVRLDGVYIAICHYVRPGL-SVNI--SHLITYHRYLRFFPNGQVLSLLANEEHSPKHIVPILMTLKLRSRGRWNIL Lenti61 AVEVYRKAVLHEQRSELDDALRLYRTAFRMDIKTMPDELLLHVLRLVR-FARVNRKSLWRPLVDFRRVYIEHPRVRCDGLYIAVCHYMRDGI-GVNY--SHLVTYYRYLRFYPDGQVLSLLANEELSPSQVIPLLMILELRSRGRWNRL Malgl1 -------------------------------VQRMPDEIWHSILWHVR-LGRVCWRRLWRAIVSWRDAFVHEPRVRMNGTYIATCQYIQQGM-SVHV--LHVVEFFRYLRFFPNGRCISWLTTER--PADVVHRLMTLHMRPSGRWHRL Mellp23 ----------------------------------------------------------------------------------------------------------------------------------------------------- Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 AMDHYVVAVDNERQGKLGKALEGYRRAFKLDIARLPSEIMLHILRILY-FALVCKKSIWQYACHWMRMFIDRPRIRYDGVYISTCNYVRPGA-SDKP--IHFVTYYRYLRFFPNGKVLKHVTTNE--PQQVVKLLMRLKIKTTGRHNKL Mydma -------------------------------------------------------------------MYYQRPHIQYNGLYISVNTYIRTGE-QYKP--CHLVQYCKYLRFFTDGTVLVYASAYD--PKLVVEVM-------------- Neucr2 ALDHYEKAVEREAAGSLGDSLKLYRKAFRMDIASLPEELLVHIMRDVR-LAQVCKRRIWRRICSWLRMWRLRPRIRFNGCYISTVNYIRTGQANGSP--VHIVTYYRYLRFFRDGTAISLLTTAE--PADVVYHLLDLTLKSAAKNNKL Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ALEHFERAVEKEAEGNLGDSLSHYRKAYRLDIATVPSEVLVEILRHVR-TSLVCKRHIWRRICSWSQVFQTLPRIRFTGIYISTVNYTRAGAASNSP--IHIVTYYRYLRFYPDGSVISLLTSTE--PVDVVPHIMHLSLRSPSKNTKL Phybl2 AMDFYIAAADLEKQGQLQKAIIHYRRAFKLNIAKLPNEVIQHILRHLR-FALVCKNSLWKFACNWMRMFIERPRIRYDGVYISTCQYVRPGI-SGQP--FHMVTYYRYLRFFPNGDILKHVSTDK--PAQVVRLLMSLTIKSTGRHNKL Picst3 AILLFEKAIEKESHGLMSDAVELYRKAFKINLIHLPNDVWIRILEILQ-FSITCRKEVWRKLASWKYMLNHRPFIKFLGCYISVVNYYSEGGKASNP--VRTITYYRYLRFYPDGTCVKVLTSIE--PTKVIPHLYYYLIKSVFKHNKL Plicr1 AVELYRRAVLHEQRGEVDDALQLYQKAFRLYISILPDEILVSILRTLR-FATVNRKVIWKDFVDYRRVYIEQPRVRYDGVYIAVCHYLRQGM-SVNI--SHFITYHRYLRFLPDGQVLSLLANDEADPQEVVPQLMTLALRSRGRWNKL Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 AIDVYRRAMQAEQNSELDEALRLYRQAFRLDFVRLPDELIVDILTILR-FAAVSRRTIWRNFADYRRLYVEHPRLRLDGVYIAVCHYIRPGL-SVNI--HHLITYHRYLRFFPDGTVLSLLANEQLDPHNVIPHFMTFSLRSRGRWNKL Rhior3 AMDHYVLAVDNERQGKIGKALDSYRRAFKLDIAKLPGEIMLYLLRYLQ-FALTCKRSIWQYASQWLRMYIDRPRIRYDGVYISTCHYIRQGT-SNQP--IHFVTYYRYLRFFPNGTVLKHVTTDE--PAHVVKALMSLKLKTTGKHNKL Rhoto1 ----------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 SVHCYREATILERQGKLNEALKLYRTAFKLSFAKLIDEV-----------------------------------------------------------------------FLPAG---------------------------------- Sacce1 AIAIWEKGVLKEKDGSMSDAINFYRSALKIHLEILPDDILLRIIKKVN-LSMTCSTVPFKTFADYR-MLRERPYIKFEGVYISVVNYVRYGSNALKP--VHMITYYRYFRFYENGQCLRLLSTDE--PSAVVKHFEEFQIKNQKRYQRL Salro ----------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 ALDVYRRAVQCEQRGALDDALTLYRQAFRMELNMLPDEILVHILLMVR-FATVSQKGIWRALVDYRRLYIEHPRVRLDGVYIAVCHYVRQGL-SVNI--SHLITYNRFLRFFPNGDVLTLLANEEHAPKDIIPQLMDLQLRSRGRWNKL Schpo1 ALLHYKDAIKSEREGNLGESLNKYRLAHKVHILKLPDEVLLVILENCS-IALTCKHSLYRSFCSWKTLFLKKPRSRFDGCYISVCRYFRPGT-SNQP--IHLITYYRYLRLYPNSTCIVYQSSNE--PNDVVRNFQKLQVRGI----RL Sorma ALDHYEKAVEREAAGSLGDSLKLYRKAFRMDMASLPEELLVHILRDVR-LAQVCKKRIWRRICSWLRMWRLRPRIRFNGCYISTVNYIRAGQASGSP--VHIVTYYRYLRFFRDGTAISLLTTSE--PADVVYHLLDLTLKSAAKNNKL Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 SLEAYLLGTKYERMGNLSAALTSYRDAVRLDLAKLPSEIVTQIIHWAS-LSLVSRKSVWRFVCNWFNMWLDRPRLRRDGLYISRVNYVRTGEAQYAP--VHLVTYYRYLRFFPH-KVVCWTTTVE--PAKAVQVLCNLTLASSGKHNKL Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 AVDVYREAVRCEQASKLDEALRLYRQAFRMDLAKLPNELLTHVLRFLR-FAQVNRKTYWRRLVDYRRLFIEKPRVRLDGVYIAVCHYTRHGM-SVAI--SHLITYHRYLRFFPTGDVISLLANEEYNPQQIIPILMTLTLRSRGRWNKI Tapde11 ALEAYEKGVEKERQGMLSDALVFYRRAFKIDISSLPEEILHQILTYATPLSMTCQKSMWKELCNWKRMFIEKPRIRYNGIYISTCHYTRPGV-RTSP--IHLVTYFRFLRFFPNGECLSLLTPTE--PREVVHNIMELQIRSSGRQNKL Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 AVRIYAQAVEYEQSGRLNDALVLYRKAFKMDISRLPAEMFEPIFLHMR-FGSTCWRNVWRRLAEWRTVLIEEERVRLDGCYISVCHYVRPG--AVAVSLSHLVTYHRFLRFYPDGTVLSFLTTDH--PSDVVPILMELSLRETGRWNKI Trire2 ALDHYEKAMEKEAQGNMGESLRLYRQAYRLDIAKLPDELLVHILTDVR-LSLVCKHRIWKRVCSWKHMFRTRPRVRFNGCYISTVNYIRTGQA-GDP--VLIVTYYRYLRFFRDGTAISLLSTTA--PAEVVHHLMDLSLRSATRNNKI Umbra1 AMDYYMIAVDKERQGNLGQALANYRRAFKMDISILPNEVVVHVLRNVN-FALVCKRSIWRPLCNWLRMFIERPRIRFEGIYIATCHYLRPGI-SNQP--IHLVTYYRYLRFFPDGTIVKYLSTDE--PVHVVRNIMNVNIKSTGRHNKL Ustma22 AVEAYAHAVEMERSGQLDQALTSYRRAFKLNIASLPDEILLHILQLVI-VGRTCWKSLWREIVDWRTAFINQPRVRLNGCYIAACHYARPGL-SVRV--IHVVEFYRSIRFLPDGTALSLLTTDP--PSETVRRLMVFSLRSTGRWNKL Walse1 AVECYKQAVEAEQVGQLNDSLILYRKAFKLDISTLPDEIILNIYRHLR-FACSSRKIIWKDLVAWRKLWLDIPRIRLDGVYISVCHYLRHGE-SNTF--TQLVTFYRYLRFFNDGLVISWLSTDV--PNQSVPTIMKAKLKSSGKHNKV Zygro1 AISWWEKGVQKEKDGSMNDAIRFYREALKTHLDILPPDVLSRIVHYVN-LSLTCSTDPYRTFANYRKMLMERPFVKFGGIYISVVNYLRYGANQMNP--IHMITYYRYFRFYPDGGCLRLLTTDE--PSMVVPHFEELQIKDQRIHQRL [Cluster3447.fasta_al_trimmed; alignment length = 40] Allma1 HKPYPRWVYSPTGGWW-SQPANWKVNTAVVWRTSEEKEAE Ashgo11 ---------------------------------------- Aspfu1 KIPYPKEVWSPAGGWY-AQPANWRVNTAITWSISAEREHR Aurde31 RYPYPKDVWSPAGGWW-TRPRAWKSNTLIVWTYSAKHEQR Batde5 RAPYPKWVWTPYGGWW-THPKHAFRNSLVIFKFSAEHETR Botbo1 RYPYPRQVWSPSGGWW-TRPTNWVSNTAIAWSISAEKEWR Botci1 KIPYPKHVWSPAGGWY-SQPGNWKANTAIMWKLSAEREFR Caeel ---------------------------------------- Canalb1 ---------------------------------------- Cangl ---------------------------------------- Capow RFEFPRYVWSPTGGWW-PEPKMWKRNTLLVYNLSKRLEVR Catan2 RTPFPRYVYSPMGGWW-SQPKNWKSNTAVIWKFSNDKQ-- Cioin ---------------------------------------- CocheC53 KIPYPKHVWSPAGGWY-AQPANWKANTAVAWMLSANREYR Coere1 HKPYPKHVWSPSGGWW-AQPRQWKRNTLIIFKKSAELEQR Conco1 ---------------------------------------- Conpu1 RFPFPKHVWTPAGGWW-TRPANWRANTVVVFTVSADREVR Copci RYPYPKHVWSPAGGWW-VQPKNWASNTAIVWSVSADKERR Croqu1 QYPYPKEVWSPAGGWW-TRPNNWRTNTAIVFRLSANREQR CryneH991 QYPYPKEVWTPSGGWW-TRPSNWKGNTAIVWRLSANREER Crypa2 KSGYPKHVWSPAGGWY-AQPSNWRKNTAIVWNLSAEREFR Debha1 ---------------------------------------- Dekbr2 ---------------------------------------- Dicdi RYPYPKTVWSPPGGYWCVKPFNYNKNAKVAFLIDMNVERR Dmel ---------------------------------------- Enthi ---------------------------------------- Falba QFPYPKWVWSPSGGWW-THQPHWVRNTAICYRFSKNNEVR Fomme1 QYPYPKEVWSPAGGWW-TRPSNWKSNTAIVWQLSASREWR Fusgr1 KVPYPKHVWSPAGGWY-AQPANWRGNTLITWKFSSEREQW Galma1 RYPYPKYVWSPAGGWW-TRPTNWATNTAVVWNISASLEKR Ganpr1 RWAYPKWVWSPAGGWW-GRPKNWRTNFAIVFRFSAANEIR Gloin1 RYPYPKEVWSPAGGWW-SRPANWKSNTTIVWKISAEREWR Hisca1 RVRYPKHVWSPAGGWY-SQPANWKTNTAIAFSVSADREFR Klula1 ---------------------------------------- Lacbi2 RYPYPKAVWSPAGGWW-VRPSNWASNTAVVWSISAAHEKR Lenti61 RYPYPKEVWSPAGGWW-TRPSNWKSNTAIVFTVSADKERR Malgl1 ---------------------------------------- Mellp23 -----------------------------VFKLSADREQR Mnele ---------------------------------------- Monbr RYAYPKYVWSPAGGWW-AEPRSWKANTIMLAYLSSQREVW Morel2 RYPYPKHVWSPSGGWW-TQPTNWKSNTAVAWKYSAENEER Mucci2 RYPYPKDVWSPAGGWW-SRPKTWKTNTLVVWKVSADKEVL Mydma ---------------------------------------- Neucr2 QVPYPKHVWSPSGGWY-AQPANWKKNTAVVWKLSAEKEYR Orpsp11 ---------------------------------------- Pench1 KIPYPKEVWSPSGGWY-AQPANWRANTAIAFSISADREYR Phybl2 RYPYPKQVWSPAGGWW-AQPKTWKSNTAIVWSVSAEKEVC Picst3 ---------------------------------------- Plicr1 RYPYPKTVWSPAGGWW-TRPSNWKSNSIIVATVSWAHEWR Polpo ---------------------------------------- Pucgr2 RYPYPKEVWSPSGGWW-TRPTNWRSNTAIVFKLSANREQR Punst1 RYPYPKHVWSPAGGWW-ARPSNWKTNTAITWNISKDKEWR Rhior3 RFPYPKEVWSPAGGWW-SRPSNWKSNTAVVWNVSAKKEVR Rhoto1 QYPYPKEVWTPAGGWW-TNPHNWRTNTAYIFKFSAEHEER Rozal11 ---------------------------------------- Sacce1 ---------------------------------------- Salro KFPYPTKVWSPAGGWW-PAPKNWKANTIIAYIIS-ERRMR Schco3 QYPYPKYVWSPTGGWW-GRPAAWKANTAVVGLAGEARAER Schpo1 ---------------------------------------- Sorma RVPYPKHVWSPSGGWY-AQPANWKKNTAAVWKLSAEKEYR Sphar ---------------------------------------- Spipu1 KYPYPKWVWSYYGGWW-PSPKRVVTNSLIVWNFSANHELR Sporo1 HFPYPKEVWSPAGGWW-TRPSNWKSSTGFIWSYSARKEVS Stehi1 RYPYPKAVWSPAGGWW-GQPRAWKTNTAVTWTISAEHERR Tapde11 RYPYPKQVWSPAGGWW-SRPKNWASNTVVVWSVSARIETR Thetr ---------------------------------------- Treme1 HYPYPKEVWSPAGGWW-SRPKNWATNTAVVWRVSARNE-- Trire2 KVPYPKHVWSPAGGWY-AQPANWRANTFITWKFSADRERW Umbra1 ---------------------------------------- Ustma22 RYPYPKEVWSPAGGWW-TRPNNWVSNTAVVWTYSADREWR Walse1 QFPVPKDVWTPAGGWW-TNPRNWKANTAVVWNYSASKENR Zygro1 ---------------------------------------- [Cluster3451.fasta_al_trimmed; alignment length = 91] Allma1 ------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------- Aspfu1 ------------------------------------------------------------------------------------------- Aurde31 DDDSDDDV-GPKPLPFIEREEQREEWML-KPPKLTAKRTFNRTETPEERQKRVRSESLLEIHWNHDRDIMD-ASARKKLVDAK-GLSDRFG Batde5 RDDSDDDV-GPRPLDIEARLGKREDWMT-LPPQM-TSRQFSSIESPKDREKRIRPKTLMQDFFDRDKDIID-AKGRKRLLDAQ-KLDSKFA Botbo1 DDDDDDDY-GPMPAPFLAREEQRDEWML-VPPKL-RARQFSKTETPAERQARLRSAPLIELHWDRDRDMMD-DASRKKLIDAR-GLGDRFG Botci1 DSDSDSDY-GPS-LPA-REAQQRPEWML-APPKL-KARKFAGTETPEEKRQRLRGKSLYEAHFDREKDMLG-HAKKKELLKAA-DFGSRFQ Caeel GDDSDEDI-GPMPVAVLQKEAKREEWMTSVPKGL-GARTFKKEDAPGAKKRRNSGPSLLEIHFDREKDMLK-PGGSKEAVRMK-EFADRFA Canalb1 ------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------- Capow AEDDDDD--GPLPAA-------REEWMMELPEGT-EARSFRSTDTPAQRAARLASLSLVDMHFTFDREKMD-SKKRNDIIKSK-SFNTRFA Catan2 DSDSDDDV-GPR-PPEEARAEQRGEWML-VPPRM-KSRTF--TETPAEKADRLRGESLTESYFDRDRDVIS-AKDRAKMVEAK-TLDSKFS Cioin SDSSDDEI-GP--LPFENRSVEREEWMLELPPGM-GPRQFRATETPGDKNKPKRKESLYSMHFDRDTDLFD-KAMKKQKL--S-DLSSRFS CocheC53 DS-SDDDF-GPA-PPFDTEPQQRDEWMT-LPPKM-RARKFNTTETPEQKLKRLRGKSLVEEHFDYKKDMTT-HKQRREMLKSK-GFSDRFS Coere1 AESSEDSV-GPS---LDAQMETREEWML-VPPSI--------TLTPEQRRKQARPKSLMEMHFDRNRDLTEKKSGRSQQHDAMGTLNDKYA Conco1 GALPAEDI-GPS-FPIEQRHQKREEWMV-VPPNL-KNRQFNQTETPQQKYNRIRGKSLMDEYGNREGDILN---------DMG-GLASRFK Conpu1 DDDSDDDI-GPKPLPFLEREEQRDEWML-VPPRM-KARQFAKTETPAERQQRIRGSALVDAHWDHARDMMD-DSTRKKMLDAK-SLGDRFS Copci DDDSDDDV-GPKPLPFIEREEKREEWML-VPPRLKKGRQFSKTETPAERQKRLRGGALVDQHWDHARDMMD-DGKRKQMLEAK-GLGSRFS Croqu1 DDEEQDEFAGPMPLPLREREEKREEWML-VPPKI-KSRGFKQTETPAERAQRLRGASLLDLHWDHDSMMMS-DKQKADMIDAK-GLGGRFG CryneH991 DDDSDDEVIGPVPVPFLEREEQREEWML-VPPKK-RATTFSRTETPAEKAQRIRGPSLLNQHWDHDRDMLS-DQERSRKIEAG-GLGDRFG Crypa2 DDDDDDDY-GPS-LP------KRDDWML-APPKI-RSRKFASTETPEEKARRLRGKSLYEEHFDREKDMIT-ASQRKQLLRAS-DFGGRFS Debha1 ------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------- Dmel EAEDDDDF-GP--LPLEERALVREEWMLELPD---MKRTFYQTKTPQSEADAAREESLVELHFSRDVDLID-KNQTKQIVKAK-ILNTKFS Enthi ------------------------------------------------------------------------------------------- Falba --DDSDD--GP----VSQAQRKREEWMTVLPDGP-SRKRLGSTDTPA------AGPSLMDSY-PFNPLVQK-SAAQKNKMRSI-MGDAYGH Fomme1 EDSDNDDY-GPMPLPFLEKEEKRDEWML-VPPKL-KARQFSRTETPQERQQRIRDKTLLEMHWDHARDMMD-EKQRGKLIDAR-SLGDRFG Fusgr1 DSDSEDEY-GPA-LP------QRDSWML-APPKM-RNRKFASTETPEEKLKRLRGKSLYAEHFDREKDMIG-TAQRRELMNAA-DFGGRFQ Galma1 DDSDDDDV-GPKPLPFLEREEQRDEWML-VPPKL-KARQFSRTETPAERQQRLRGAALVDQHWDHSRDMMD-DEKRSKMLEAK-GLGDRFG Ganpr1 -----DPI-GPDFGPLERRARKRGDWML-IPPNLFKNRGFSQTETPEEKEKRFRGPSLLDSHWDRERDLVD-PKLKAEMLKSK-ELGGRFG Gloin1 EEKEEEDI-GPI-LPFEERAEQRGEWML-VPPNM-RSRQFKKTETPAEREERLRPKSLLETHFDREKDVMD-SRKRKEFLNAK-GLGSKFG Hisca1 DSESDDGY-GPS-LPKGQNESQRDDWML-HPP----------TETAEDKRKRLRSKTLYAQHFDKEKDIIN-HAQRRELLRSS-DFNSRFS Klula1 ------------------------------------------------------------------------------------------- Lacbi2 EEDDDDDF-GPKPLPFMEKEEQRDEWML-VPPKL-KGRQFSRTETPAERQQRLRGPSLIQQHWDHSRDMMD-DDKRNKLIESR-GLGDRFG Lenti61 DEDDEDDV-GPRPLPFLEREEQREEWML-VPPKLTRPRQFARTETPAERQQRIRGPSLLKQHWDHGRDMLD-DKTRNKFIEAK-GLGDRFG Malgl1 ------------------------------------------------------------------------------------------- Mellp23 DSEEDDGVTGPMPLPLREREEKREEWML-VPPKI-KSRGFKQTETPVERTQRLRSSSLLDLHWDHDSMMMG-EKQKADMIDAK-GLGGRFG Mnele ------------------------------------------------------------------------------------------- Monbr DSDSDDDI-GP--MPFERRAKERESWMTELPEGM-DNRSFRQSAQPGSEAP--RGQSLVDMHFDPDVDLIS-ADKQRQMIKAS-SFQSRFA Morel2 DESSDDDV-GPV-LPFEERAETREDWMM-VPPKI-TARTFQKTETPADREKRLRGTSLMEAHFDREKDVVD-HRQRDELVQAM-DLGSKFS Mucci2 DQ---DDV-GPA-LPIEERARERPEWML-VPPSG-KSRQFTNTETPAEKQRRLRPLTLLEMHFDREKDLIS-KKDKDEFLKST-ELGSKFG Mydma DDSEEDDI-GPS-LLIEQRAEERESWMLELPPGL-GPRTFRATETPASREHKRRPQSLLEMHFDREADLLN-RSNPKETASAK-SFSDKFS Neucr2 DSDSDDGY-GPA-LPF-AQQQKRDDWMI-APPKL-KSRKFASTETPEEKIKRLRGRSLVEEHFDREKDMIS-HTQRKDLLRAA-NFGDRFQ Orpsp11 KSEEDDDI-GP--LP--------------LAPEL--------TE--EEETQRI---------------------------RMKRKLEGKEE Pench1 DDDDDDDF-GPS-LPVSTASSQRDQWML-QPPQL-RNRKFNTVETPEERMRRLGKNSRLETPFDREKDMIS-SAQRREMVKAA-DYNTRFT Phybl2 DA---EDI-GPV-LPIEERARERPEWML-LPPSG-RSRTFNNTESPSDKKNK-RPLSLMEMHFDREKDLMD-KKQKKEFMQSG-ILDDRFG Picst3 ------------------------------------------------------------------------------------------- Plicr1 DDDSDDDV-GPMPLPFMEKEEKRDEWML-VPPKL-KARQFARTETPAERQQRIRGSTLVDMHWDHSRDMMD-DKTRSKMLDAK-GLGDRFG Polpo ------------------------------------------------------------------------------------------- Pucgr2 DEEEEDEVAGPAPLPLKEREEKREEWML-LPPKI-KARGFKQTETPAERSQRLRNASLLDLHWDHDAMMMS-ENQKADLIDAK-GLGGRFG Punst1 DDDEDDDF-GPRPLPFMEREEERDEWML-KPPKLSRPRKFNTTETPAERQQRLRGDTLLAKHWDRDRDLMD-DKTRSRIIDSA-GLKDRFG Rhior3 DE---DDI-GRA-LRLEERAR-----------SS-RSRQFSNTETPADKERKLRPLSLLEMHFDREKDLMN-SKQKKEMLQSS-QFGDRFG Rhoto1 SDEEDDSV-GPMPLPFREREEQREEWML-VPPKL-KSRGFATTETPAERQQRLRNQSLVDQHWDRDRDMMD-DHQRANAINAK-GLGGKFG Rozal11 ------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------- Salro DGDDDDDM-GP--MPFDEWDQQREDWMTELPEGV-TNRTFKRTATPNAEGKR-RNESLMDMHFDRERDLVS-QSARDRMIKAA-GFHSRFT Schco3 DDDSDDDV-GPKPLGFLEVEQQRESWML-TPP---KKRTFSTTETPQERLQRLRGPSLTEAHWDRDRDLFS-DGERKKALDARSGLGERFG Schpo1 ------------------------------------------------------------------------------------------- Sorma DSDSDDGY-GPA-LPF-AQQQKRDDWMI-APPKL-KSRKFASTETPEEKIKRLRGRSLVEEHFDREKDMIS-HTQRKDLLRAA-NFGDRFQ Sphar ------------------------------------------------------------------------------------------- Spipu1 EVDSDDEV-GPKPAPFEERERVRGDWML-VPPSM-KSRQFSKTETPQDREKN-RGKALMDQHFDREQDMID-AKSRQEMLQAR-KLDSKFG Sporo1 ------------------------------------------------------------------------------------------- Stehi1 EEESEDEV-GPVPLPFLEKEEKREEWML-VPPKLTKSRQFSRTETPAERQQRLRGPSLIDAHWDHSRDMMD-EKDRRKMIDAK-GLSERFG Tapde11 DDEDEDDI-GPK-LPTLATADVRPDWML-YPPKL-KSRTFATTKFPGKSVSRKRGPSLYDQHFDREKDIFTKTKEFAK--NSK-DLSSMF- Thetr ------------------------------------------------------------------------------------------- Treme1 DEDDDDEI-GPKP--FLEREKKREEWML-VPPRK-RPTTFNRTETPAERIQRERGPSLMEQHWDREKMLLS-ESERAQKIDAK-GLNDRFG Trire2 ESSDDDSF-GPS-LP------KRDEWML-APPRI-RARKFASTETPEEKLRRLRGKTLLEEHFDREKDMIT-ATQRRELIKSA-NFGGRFQ Umbra1 QE---DD--------IEERARQRGDWML-VPPQG-KSRQFSKTDTPADKQRKLRAMSLMDMHFDREKDLMD-YKRKQEMLRAG-ELSSKFG Ustma22 EKERGQR--DSIVA-AARRDREKRSSRHSHSDRR-KRHRSRS-DKPKDRHERTSRSRSRDRDWDRDAALMD-QTKRSKMMDAH-ALGDRFG Walse1 ------------------------------------------------------------------------------------------- Zygro1 ------------------------------------------------------------------------------------------- [Cluster3473.fasta_al_trimmed; alignment length = 256] Allma1 AVLLAVCLVAFLIQSEVTSHVQNRVNYKKPYFMLWFAHSFYAVFHFL----AVRA-LILAFLSALPSYLWYMAAGLTTMGNLTAIYNTSAFWAYAFSIWFCVAGERFAKISAVFVSLVGVACISL--LGNLVALAGAVAYGLYEALYKKYAAFANFFTGCIGVFTVLVLWIPIPILHILGVEPFE-IIVALMGLAFNACFMLLIAFTSPVMAAVGIMLTIPCIAVTDLAIIPWNSVLGSSLICLGFLVLASRD--- Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 SGFLLLSLASFVVQTETAVYIQHELHWDKPYCMLYLTHGSWCLVQLLILRIMLRTTAFVTVALTIAGGSWYVAVNLTTASDLTAIYNCSAFFAYAFSIPLL--NDKLRKVFSVVVAIVGVLVVAYRLWGNIIIGVGSVLYGLYEVLYKRYAIFANTFGSLIGCFTLLVLWIPLPILHMLGWEEFR-V-SVAANATFSGCFLVLISLTSPVLSSVAALLTIFLVAIVDWLRLSAASIVGGLLIIVAFFLLSWSTYRE Aurde31 LTLFAAILIAFCIQSALTEYVQGTLEYRQPFLLFYIAHSSFSILHLAWLSLFLTVVAALTVGATGPGLLWYASVSLTSISDITALWNANALWAYALAVPIL--RAPWSAACAVLMAFFGTLAVVYPLLGAGLAFGASVAYALYQVLYKRFVLYPNALTSSIGLGTFLLLGLPPP-------------AIAANGVVFNSGYLVLLGLWGPVLTSVGSLLTIVLMLAYDLVVLTIWSFAGSGAIIAGFAVLMLDVVQI Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 TVLFVVVLGAYVVQSQLTQYVQSDLAYRQPYLIFYIAHSSFSVLHLLYLTILLRAVLLLTGGATVPSLLWYVSVSLAPISDVTAIFNTHAFWAYVLTVVIT--RAKWEKLAAVLLACIGVFVVVYALVGDAITLTAAFMAALWEVLYKKYIFHANFFTSGIGVGTLLLLWLPLWLAHSTGVYKVA-LGIATAGLVYNAGFMILLGVWGPVIASVGNLLTIVLVMISDIIVVTPGSILGSFMIVGAFSVLVVDILGR Botci1 AFFLGLSLISFVIQTETAVYIQHQLGWNKAYCMLYFTHGSWSLTQLLILRLMLRMTAFVTCALTVAGGSWYVAVNLTSPSDLTAIYNCSAFFAYAFSVPLL--KEPLRKSFAVMVAIVGVLIVAYRVLGNLVIGVGSVLYGFYEVLYKKLAIFANTFGSLIGTFTLLVLWIPLPILHLTGLETFE-L-SVLANATFSGSFLVLISLTSPVLSSVAALLTIFLVAIVDWAFLSPAAIVGGLLIIVAFLLLSYSTFRE Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 VILFIVSLTSFVFQTEFTSQAY-KLKFSEPVVLLAVTHGSWWLIQIIFVSLVIIKAFIITVVLTLAGFTWYGAMSMTYPSDVTAIYNCSAFTAYAFAIPLL--NEKFSKASSVIIALSGVFIVAYRFWGNLLILTGAVLYGYYEVLYKKYLTFANFVMGFFGIYTLTILVTILIFAEVFHIHHFN-LGSIVSNLLFSASFLSLMALTSPVLSSVSSLLTIFLIGLVEWWVLGFQQLVGDLLVIVGFVMLTIASWKE Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 GVLLLICLVAFIVQSEITAFVQNRIHYRKPYFMLWYSHSCYTLFHFLFC--ALR--------------------GYTSMSNVTALYNTFTFFALVFSVWMSVDGERLHNVSAVVASLLGIAAITFAWFGDLMAVTGAATYGLYEATYKKYASFATVVTGMIGVFTLLVLWIPIPILHWVGHETFQ-WLIALTGIMFNATFMLLIAFTSPVMAAVGIMLTIPCVAVVEVAMVPFGTVVGSVVICIGFALLVSGYTGD Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 AFLLALSLISFTVQTETAVYIQHQLKWEKPYCMLYMTHGSWVVATLALLRFMVKMTAFITCALTLAGGSWYVAVNMTTASDLTAIYNCSAFFAYAFSIPIL--HEKVRKVLAVAIAIAGVFVVAYRAFGNLVIGVGSVLYGLYEVLYKRLAIFANLFGSLIGTFTLSVLWIPLPLLHWLGWEIFE-L-SVLANATFSGAFLALISLTSPVLSSVAALLTIFIVALVDQLLLTPAAIVGGLLIIGAFSLLSWASYKE Coere1 GAALVICIFTFVAQTAITRQVQQ--SFTKPYFMLWVSHSFWALLHTLY---AMLMALLLVAMLNAATYLWYVAVGLTSMSKVTAIYNTSCFFAYLFSVLLL--NERVQKAAAVVVSIVGVVFMALELLGDLLSLVCACGTGLYQVLYKKYAYAVNFMTTLLGLATLLIFWLPMPALDAAGVEPFQ-WANGLLAIAYYGGFMIALALTSPLFAAIGVMLTIPITAVVDMLILPWNVFVGGAAILVSFCILFFAEYRD Conco1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 AGVFALVLLAFVTESQLTQYVQTKLDYRKPYLIFYLVHSSFSALHILYLVLFLVLCAIMTTGISIPGLLWFAAMALASVTDVTAIWNTNAFFAYIFTVKLM--KLKWGRLVAVCLATIGVLIIVYPMVGDLLTLVASAGYGLYQVLYKKNVLHANLVTSTIGLMTLVTLWLPLPILHFYGVEPFE-LAICISGLIFNSGFMILLGIWGPIITSVGNLLTIVLTLISDLVFLTVWSLLGAGMIIGAFGVLVYEMRT- Copci IAIFVFTLLAFVVESQFTQYVQTDLGYRQPFFIFYLVHASFTILHLAYLTWFTKLITLLTIGITCPGLLWFAAISLATVSDVTAIWNTNAFFAYLISVKLF--RLKWEKLFAVVLATIGTLVVVYPLIGNLLTLVASFGYGLYQVLYKIYALHPNFLTSIMGFITFVVLWIPIPILHWTGIEPFA-WGIALGGVVFNAGFMILLGVWGPIVTSVGNLLTIVLMLISDV-----W-------LSIPFIPHPPDIQNV Croqu1 FLIFPLVLIAYTVQSELSQV--IQRTYPKPYLLLYLTHSAYLIFHLLTLKLFALRSIQLTLLIALPSLSWYASVSLTDLTSITAIYNTNAFFAYLFALAFL-RSERLEKLIAVLAALLGVLIIT-RLLGTGLAFAGSLSYAAYEVWYKKVVLHANLITTTIGFFTLTLLWIPIPILHWCHWERFA-LGMVSMGVIFNAGFMVLLGLWGPVVASVGNLCTLVLVAIADAVFLTLPVGLGCLLITAAFSILMGDMMKS CryneH991 FFILGGIVIASAAQTEFAHYVAAELHYDQPYFSFYLTHSTFSFIHLLYLSLWCRKVILLTILVTVPAISWFIAMQYSTPVDITSIYATSSFAAYGFSLLLL--KEPLNTVWSIILAFMGVIIISIRALGDSIMLFGALALGLYEVIYKLALLHANFLTSCIGIATLLLLWPPIIWLDWMGYEVFK-WVVAWGGSIYNAGLMALIGIWGPTTSSVANLLAIGLVAIVDALW-DLQTFIGVGMICAGFGVLLWQGEG- Crypa2 AVFLVISLVSFCVQTELAAYVQHDLGWNKAYCMLYLTHGSWALTQLLILRLMLKTTVFVTSALTVAGLSWYIAVDLTTPSDLTAIYNCSAFFAYAFSIPLL--KEPFRKGFAVVIAIVGVIVVAYRFLGNVIIGCGSVLYGLYEVLYKRFAVFANLVGSLIGCFTLLVLWFPLPLLHIAGIERFA-L-SVVMNATFAGSFLVLISLTSPVLSSVASLLTIFIVAVSDWFLLSLAAIVGGLMIIVAFVMLSVSTWRE Debha1 SLLFVASLASFVLQTELTSHVF-QLGFNEPVVMLLVTHGAWWITQVLLISIIFVKSAIITVILTVAGGSWFVAMAMTYASDVTAIYNCSAFTAYAFAIPIL--HEKLSKASSVVAAVAGVFIVAYRLWGNLIIFIGAILYGYYEVLYKKFTTFANFIMSLFGVFTAIILVIVIVFGEIFHIHSFN-FGSSIANILFSALFLSLMALTNPVLSSVSSLLTIFLIGIVEWFLLSFQQLLGDCFVIIGFIMLTTASWKE Dekbr2 VVLFILSLASFVLQTELTSILFIKYEYDDPFFVMLLTHSCWWLIQFVSVALLLKSALLLCLVLNVAGATWFVAMKLSTGADVTAIYNCSAFAAYCFSIPIL--HDSFSKMSSVLTAISGVMIVAYRFAGNVIILVGAILYGLYEVLYKRKCTFSNFTMGLVGINSCILLCTCLFFAHLFGFYSVK-LTSVFSNAVFSLSFLGLMSLTSPVFSSVSSLLTILLVGFSEWWFLGWYKIFGYCLVMVGFALLTYASWSE Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 TIIFILMLLGFVAESQLTEYVESSRNYRQPYFLFYIAHSAMTLLHLLYLRCLLAVITWCTVGITTPALLWFVALNYASVSDVTAIWNSNAFWAYVMSVKLK--HTSWERLAAVVIASIGVMVVIYPFFGNMLALAASVTYALYQVLYNMYALYTNALTSGIGIMTLIALWIPMPILHLTSIEPFV-WGIGVSALTFLATFMIMLATWGPIVTSVGGLLTTVLVIISDLIFLTLWTVIGAGMIVFAFAALAYESLNA Fusgr1 GFFLIVSLIAFCVQTELSAHIQHDLGWDKAYCMMYFTHGSWVVIQLLILRFFVRFTAIITCALTVAGLSWYIAVSLTTPSDLTAIYNCSAFFAYVFSVPLL--HEPLRKSVAVLIAIAGVLVVAYRFFGNLVIGIGSVLYGLYEVLYKRYAIFANTFGSLIGLFTLTVLWIPLPLLDFLNIEKFE-I-AVLSNATFSGSFLVLISLTSPVLSSVAALLTIFLVAIVDWMILSFAAIVGGAMIIIAFLALTWSTYRE Galma1 VGIFVFTLLAFVTESQLTQYVQSNLGYRQPFFLFYLVHSSFAILHLLYILGFIWLVLGCTLGITCPALLWFLAVSLASVSDVTAIWNTNAFFAYLISVKLF--KLKWERLLAVVLATLGTIAVVYPLLGNLLTLVASFGYGLYQVLYKIYALHPNLLTSLLGFSTLVILWIPIPFLHWSGAEVFR-LGIAFSGVVFNAGFMVLLGIWGPIIVSVGNLLTIVLVLISDLLFVTFWSLTGSGVIVLAFGVLAYDMFTK Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 LSILCIGIASFVIQTELAQFVQTGIKFHKPYFILWVAHSCYMILQFMFRL-ILKISLLFACGICISGYIWYIAVNLTTMAKLTAIYNTSCFWAYVFSIILL--SESIKKIIATFLSITGVVIMTFIVMGDLLACFGALMYGLYQVLYKKLGLFANTITGLIGVHTFLFLWIPIPLLHFTGIELFE-LLIAIAGVFFNASFMLVIALTSPLFAAIGIMLTIPIVAWADLIVITVSTVVGSF---------------- Hisca1 ---------------------------------FYLTHGSWIFVQLLLLRIILRTTALVATSLTVAGGSWYVAVNLTTASDLTAIYNCSAFFAYAFSIPLL--NDKLRKVFSVVVAIVGVLVVAYRALGNIIIGVGSVLYGLYEVLYKKLAIFANTFASLIGTFTLFVLWIPLPILHILGIETFE-L-SVIANATFSGSFLILISLTSPVLSSVAALLTIFLVALVDWKLLTSASIYGGILIVIAFLLLSWSTYRE Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 VVIFVLTLLAFVIESQLTQYVQTTLRYRQPFFLFYLVHSAFAIIHLLYLITFLRLILAMTLGITVPALLWFAAVSLAPVSDVTAIWNTNAFFAYLISVKLF--KLEWERLFAVLLATLGVIVVVYPLVGNLLTLVASFGYGLYQVLYKIYALHPNLLTSAIGLTTLILLWIPIPILNATGAETFR-LGIALSGVVFNAGFMILLGIWGPIITSVGNLLTIVLVLTSDVIFLTVWSLLGSGVIVVAFGVLAYDMFKT Lenti61 VGLFVVCLFAFVAETQLSQYVQADLGFRQPYLLFYIVHSTFAILHILYLSVLLRLCLLLTLGMTLPSLFWFIAVVLAPVTDVTALWNTNAFFAYVFACLIS--GVKWDRLVAVLVATTGALAVVYPLVGDLLTLTASIIYGAYQVLYKMYALYPNMLTSGIGVCTLLTLWIPIPVLHFLDIEHFA-LGIALSGSIFNAGFMVLMGVWGPIVTSVGSLLTIVLVFISDAIFVTLWSILGCSAIVLAFGILAYDMVRR Malgl1 IIVFLCILAAYTVQTESIQYIQHTLGYQKPLFLLFVTHSSFVFIYLGFIHVLLAILLVLTVALTVPSVSWFLAVPLTSMANITSIYNTFSLWALVFSVYFL--QEPWSQAVAVLLGVLGVAISAY--LGDALALVGAISMAAYEIFYKRLTLHPIAMTTGIGAITFALLWIPLVIMHATGGESLE-ALSVVCGVLFNGCFAILLSLWGPVLASMSCLLTTVIVQLTDVALFSWIGMLGNLIITVSFVCLL------ Mellp23 ILIFIIVLISYVTQSELSQIIQIQNDYQKPYLLLYLTHSSYLFLHLLIIRLFLIRSIQLTFLIALPSLSWFASVSLIDLTSVTAIYNTNAFFAYLFA-------------------------IC-RLLGTALALLGSLTYAGYEVWYKKLILHANFITSSIGFFTLTLLWIPIPFLHFFKMEIFE-LGMISMGVIFNAGFMVLLGLWGPVVASVGNLCTLVLVAISDLILLNLSISIGCILISTAFIVLVIDLFHK Mnele ------MFLCFCIRTT--------------YMVAFLPYALWKF--------MFTRACILNVLGYISGYTWYMSLPITSVSANTAIYMCACAAVFLISIPVL--REKITKVMSLLICCTGIVLVSLSVLGYILVLISMFMYASYEVFYGYLL-----LVGYLGITTPVLFGLSLPIWHFTGWETLM-L-SIILDAVFNIFLLLAIALSNPTLASVGQSLALPGSMVADLIIMPWPALVGAGCVFCGFCGFVYEELRH Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ------------------------MGYHKPYFILYISHSFWAIAQFVY---LFWLTFGMTTLFMVPSYLWYACVAMTSMANLTAIYNTACFFAYLFSILLL--REKIVKVVAVFLSLLGVAVISLSMAGDVLALVGAALYGFEEVVYKKYATFANTLTGLMGVVTLTMLWVPIPLFHWIGHEIME-LMIATLGLIYNGCFMIVVSMTSPVFAAVGVMATIPLVALTDWALIGWGNVVGGLSILAGFAILVRENRKR Mucci2 TVMLTICIITFVLQTELAQFVQKTTNYSKPYFILYISHSCYVFLQLI----VIKTSLCLSVLLTLPAYIWYLSVNLTSMSNLTAIYNTGCFFAYLFSILML--HDRLVKVGAVMLCMAGVLAMACDWIGIAVASVGAALYGFYEVYYKKYALFANTITGIIGIVTFLLLWIPFPLLHFTGIETFE-LAIASMSVIYNATFMAVIALVNPVFAAVGVMLTVPAVAITDVLVVPASTIVGSALILIGFYVLNKQVGDE Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 AFFLLVSLVTFTVQTELASIVQHDLGWDKAYCMLYLTHGSWVFLQLVVLRLLAYTTAGVTCALTVAGLSWYLAVSMTTPSDLTAIYNCSAFFAYAFSIPLL--KERLHKIVAVAIAILGVLIVAYRFLGNIIIGVGSVLYGLYEVLYKRFATFANTFGSMIGMFTVFVLWIPIPILHWTGIEPFE-V-SIVMNMSFAGSFLVLISLTSPVFSSVASLLTIFIVAMSDWFMLSGASMLGGVFIMMAFGLLSWSTWKE Orpsp11 ---------------ELIRNLEINLKYNKPYLIVYFQHASNILLKPIFTKL----IFIMALLQFIPYYLWYFAINHSNVSDMMVISNSSSIFTYILTIIIL--NEQISKLLGIALSFTGVIYMSLRIVANILAVVGSILFGLSDVIFTKYVQILMMVSGLIGLVSLFMFWPGIPILSKLGFEPFE-IFISVLGFVYNYCYNYGSTLSGTVTFTCGLMVSLPITILSDYFIIRQSDIISSLLIIVGEFIMIGSNRGD Pench1 SGFLLLSLVSFVVQTETASYIQNELGWKKPYCMLYMTHGSWSFVQLGILRLMLTTTAFVTTALTVAGGSWYVAVNMTTPSDLTAIYNCSAFFAYAFSIPLL--NEKLRKVFSVAVATIGVMVVAYRLLGNIVIGVGSILYGLYEVLYKRFAIFANTFGSLIGVFTLLVLWIPLPFLHWIGWETFE-W-SVGANATFSGSFLVLISLTSPVLSSVAALLTIFLVALVDWFRLSMASIIGGILITVAFFMLSFSTYRE Phybl2 TVMLTICIVSFVLQTELAQYVQQTTDYQKPYFILYVSHSCYIFIQFL----IISTGLWLAILLTLPAYLWYVSVNLTSMSNLTAIYNTGCFFAYVFSVWLL--HDRLMKIAAILLCMIGVFLMAFQTLGISVAVLGAALYGFYEVYYKKYALFANTVTGAIGIITLLILWIPLPVLHFSGYETFE-LGIASMSVVYNATFMCVIALVNPVFAAVGVMLTVPAVAVTDVLVVPGSTLVGSILILIGFYILNRQVKNE Picst3 TFVFILSLVSFVTQTEFTSQAY-QLGFSEPVVLLLVTHGSWWILQAIGVSLVVKKALLITCLLTVAGSTWYGAMAMTYASDVTAIYNCSAFTAYAFAIPIL--KEKFSKASSVVIAVLGVFIVAYRFWGNLIILIGAILYGYYEVLYKRYLTFANFVMGFFGFFTCLIVLTIILIAEVFRIHSFN-FGSIFLNLIFSASFLTLMALTSPVLSSVSSLLTIFLIGLVEWVMLDFQQLLGDFLVIVGFVLLTIASWKE Plicr1 VALFVFTLLSFVAESQLTQYVQTTLDYRQPYLIFYIVHSAFFVLHILYLIV---IILGLTIGLTVPGLMWFAAISLASISDVTAIWNTNALWCWVFTTYLF--KLKWERLIAVLLATFGVFIVVYPLLGDAMTLVASVLYALYQVMYKKYALHANLLSSAVGLCTLLVLWIPIPILHYTGIEVFV-FAIALSGVAFNGGFMILLGLWGPVITSVGNLLTIVLVLITDVLFVTVWSLVGSGIIVAAFGLLAYEMVNA Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LIIFILITFAYVIQTELTQA--VQRTYQKPYFLLFLTHSGYIALHLLILKIFIKRSIQLTLFLALPAMCWYGAVPFADMTSITSIFNTNAAFTYLFAVCFI-DSERFEKTIGVLSSLFGALMISWRLLGISLALLGSIGYALYEVWYKSVILHANLMTTMVGLATLCLLWVPIPLLHWSGIERFE-TGIIIMGVLFNAGFMILIGLWGPVIASVGNLCTLVLIAIVDHTLLSL---VGCASILLGFSILNF----- Punst1 IILFVATLVGFVLESQLSQYVQTTLTYRHPFFLFYIVHSAFALLHVAFLLGFGIFVFVLTMAVTTPGILWFAAVSMAPLSDVTAIWNANAFFAYVFSVKIF--KLKWEKLAAVVLATLGVLAVVYPLVGDLLTLCASVGYGLYQPLYKKHALYANLLTCAIGLCTFLVLWIPLPFLHWTGIEEFA-LGIAVSGMVFNAGFMILLGVWGPIVVSVGYLLVIVLVFLSDMVFVTLWSISGAAAIVVAFGVLAVDMLKS Rhior3 TVMLTVCIITFVLQTELAQYVQKTTNYSKPYFIFLVQD-------------IVKTTLLLSILITLPAYIWYLSVNLTSMSNLTAIYNTSCLFAYLFSIVML--QEHIMKVVAVMLCMLGVLAMAYSWVGILVSCIGASLYGFYEVYYKKYALFANAVTSLIGLVTFLTLWIPIPLLHLADIEPFA-WAIASMSVIYNATFMVIIALVNPVFAAVGVMLTVPAVAITDVLVVSSSTIVGSLLILVGFYILNRQ---- Rhoto1 AVLLGIVLVAYTLQTELASYAQHELGYKKPYFLFYLTHSSYISLHLVVLALMARKALILTFFISAPALSWYAAVPLTSMTDITAIYNVFAFWAYLLSLYYL--PTPATNLVSVLLAVCGVFVIAYRLVGNGLALFGSLAYAGYE------ILYSNTITSLIGLCTFGLLWVPIFVLDWCGWEKFE-WGIAAGGIVFNGGFMILLSLWGPVTASVANLLTLLLVSLADALFMTTSTLIGGAMIVGAFAGLIVAE--- Rozal11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 VILFAIVLAAFVVESELAQYVQTTLEFRQPFFIFYVVHSSFAILHVLYLRTFITLVLTLTLGMTLPGLLWFAAVSLAPLSDVTAIWNTNPFFAYILTVKLY--GLRWERLVGVVLATAGVMVVVYALVGDVLTLLAALVQGLYQVMYKRYALHPTFLTSLVGLATGTVLWIAFPILDYLDMEPFK-LGIALSGVVFNSGFMILLGVWGPVIASVGSLLTIVLVVISDALWLTFWSICGSTIIVAAFGMLAYDVYQK Schpo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma AFFLVVSLVAFTVQTELASIVQHDLGWDKAYCMLYLTHGSWVFLQLGVLRLLAWTTAGITCALTVAGLSWYLAVSMTTPSDLTAIYNCSAFFAYAFSIPLL--KEKPRKILAVAIAIIGVLVVAYRFLGNLIIGVGSVLYGLYEVLYKRFATFANTFGSMIGLFTIFVLWIPIPILHWTGIEPFE-V-SIVMNMSFAGSFLVLISLTSPVFSSVASLLTIFIVAVSDWFVLSGASMLGGVFIMVAFGVLSWSTWKE Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 VLLLLSAIAAFVAQSEAVSIVQGPQSFNKPWFLLYVAHGCYVILQYLYCRILIRRTLCLNAFFTAGAYSWYLSVSRIALGELTAIYNSSCFFTYLLSVLLL--NERIRRLCAVFICVAGIIAISWQSVGYMFAISSSFWVAGYEVFYKKFLLLSLHITSLIGLTTLLFGVPPIFLFHYTGWESFE-IVVAALGLVFNATFMLAIAFCGPLMAAIGIMLTIPVMSSLDFFVFGWNTVIGSLAIIAGYGLLLMPSPDG Sporo1 VILLSIALAAYTLQTELASYVQHTLDYKKPYFLFFCTHSGYMLCHLIALRLLLEKVALLTIFISFPALSWYASVPFTSMADLTAIYNVFAFWAYLLSLKFL----PHEKLAAVLLAVGGVFIIAYRVLGNGLALFGSIAYAGYEVWYKIKILYSNLITSMIGLLTFSFLWIPIPFLDWIGWEAWQGFGIIGGGVLFNGCFMVLLSLWGPVVASVANLLTLILVALCDALFLTRSSLIGGGFIVAAFAGLIFGEYGA Stehi1 ILVFAFTLVAFVAESELTGYVQSSLGFRVSFSKFFVAHSSFSILHLLYLVVFVRLVFLMTLGVTIPALMWFAAVSMAPVADVTAIWNTNAFFAYLITVHLF--KLPWEKLAAVLLATIGVLAVVYPLMGDLLTLVASVGYGLYQVLYKRHAFHANFLTSAIGIVTFSVLWIFIPILHFMGAEPFR-FGIGITGVAFNSGFMILLGVWGPIITSVGNLLTIVLVYAWDILIITTWSLLGAGGIVVAFGILAYDMWRT Tapde11 GIALPISLICFTIQTELAQYIQAKLHYEKPYFMLYITHSSWWL---CWLRFMLLVIILCGICLTIAGGTWYVAVNLTTAADLSAIYNSSAFFAYAFSIPIL--HEKLRKVVAVALSIVGVLVIAYRALGNVIIAVGAVLYGLYEVLYKKYGVFANAVATGLGCFTLFVMWIPIPILHILGWEIFE-F-SVASNFIYSSCLLAMISLTSPVLSSVACLLSIFVVAIVDTHILTIAALTGGIFISVGFAVLSWATYVE Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LSILLLVVVASAIETELAYYTTTVFAYNQPYFTFFLTHVTFIFVHLLLLTLWTIRVIWLTILVSVPSISWFIAMVYTTAMDITAIYATSSFHAYFFSMLLL--KESLSTMASIGLASLGVVVIALRVLGDVIMVIGAVLLGLYEVIYKMLLLHANFLTSCLGLATLLLLWIPIVILDYTGVEKFR-SIVCWGGAIYNAGLMILIGIWGPTTSSVANLLTIGLVAVLDAVW-SFQTLLGVGMICVGFGVLLYEGE-- Trire2 AFFLVLSLVAFCIQTELSAYIQGDLGWDKAYCMMFFTHSSWVLAQLLILRLLARTTAFITTALTVAGLSWYLAVSLTTPSDLTAIYNCSAFFAYAFSVPLL--KEPLRKSVAVIIAIIGVLVVAYRFLGNIIIGVGSVLYGLYEVLYKRFAIFANTFGSCIGLFTLTVLWIPLPILHWLGLEIFE-M-AVLANATFSASFLILISLTSPVLSSVAALLTIFIVAIADWFILSPAAVLGGSMIIVAFGALSWSTYRE Umbra1 VGMLCICIASFVIQSELAQFVQQTSDFQKPYFILYIGHSSYMLLQFI----LVKISVALAIMITVPAYLWYITVNLISMANLTAVYNTACFWAYLFSILLL--GERIVKVLAVILCVFGVLIMALNPLGIPLAVAGAVAYGYYEVFYKQYALFANVVTGLIGVTSLFILWVPIPILHFSGYEIFQ-LAIALTGVMYNAGFMCLIALTNPVFAAVGIMLTIPAVAVADVFVVPASTIAGSVCILIGFAALSYELSKD Ustma22 IFAFVLSLFAYTLQTEFAQYVQQSLNYRKPFLSLYLGHSGFLLMHLFFLKWLVGLFFILTIGITVPALSWYCAVPMTSMADITAIYNTFSVWALVFSVWFL--GEKWEKVFSVLLACLGVIIVAYPVLGDLLAFVGAVTMAAYEMAFKLIGLHANVMTAGIGLTTFTTFWIGVIVANHFGWEPFE-LMVVLCGIFFNAAFMILLSLWGPVLASVSCLMTTILVEVADVLLLKWISVLGCALIGAGFAVLV------ Walse1 ILIFVSSLIAYAAETELAQVVQSRLGYSKPYFMLWLAHSSFSFLHLLLLKLSLVRMFLLTGLATFAAICWWVSVKYTTVADLTAIWNSSAFWAYVFAVYIL--GEKLQKLGAVLLACSGVVLIAYVLLGDLLVFIGSVTFALFEVCLKKYALYPNLVSTTIGLITFFTLWLPIPILHWIGWEKFE-LAMIAFGMIFNGAFIALCFIWGPVMASVGSLLTIVLVQIVDVLVLTLFSVLGGSLIILGFVLLVIT---- Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3481.fasta_al_trimmed; alignment length = 244] Allma1 LVRFRGMVQDTSLSPQVYYGDRQPVYVSVPGEHQAVV-RIGQVVEVVGVARTDLVRYLTLCGDEVAAEYVLLHLTMRGGGAGAEALQKIGVLPLSHDVLQLQL-AQGSLVVDETAMT-EGKLEHAVRNLQALASVAQARVLPCEFPYS-RVDLPIDYAILVVSESTKLVPCQVRVPLS-NAASAYLTLGDDVAKAIEQAYVTDRQCGQEQLALTRALGRSRGEATVTMDMWETVRAMEKTRIAR Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 LVRLRCFIQDNSASFETYFSEKQPYFFAVPAETHATIFQLNEIIEVIGILRQTAIDSLQLMGDALAAEYIFLQMFSRIVGYLPSALHLFVPLSMKLENLNLQL-PNSTLVVDESSLT-DGTLDRGVKNIKAIGNVIQNAEVSFGVGLGGSIQRPVDYRVLVISEGKSMFKELCTIPIL-HLLRIWIDFEPSMDERIQKEFTESQQLPVDDLNLAQLLCRSYGLGQMNDECWKQAGKLETARLAR Botbo1 LVRFRAMVQDTSLSQEIYLRERTVIWVSIPGEHIGAF-KSTEIYTFVGVLRNELISWIALGGDKEAAEWVVLTCVGKVLNPLSAILSHILPLPLSLSLLNLQL-PAGTVLVEETGMT-EGKVEKGLRNITALQQCIASQSISYVFPYS-TFSFSTDLTFIVLSEGKKFVDTDVNIRLL-EAFRRLVTISESVSKFIQDDFVKERRTTSEDMSAARVMALSMHEKEVTQCIWERVKVLDQHRKAA Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow LVRFRCMIQDTADELSMGLISRQTFVIPIPGEAGPVCVKVASVLDVVGILRSHAVDVFALLGDQLAAEYLLLHLLSNVCGKLSRTVGALVPLPLTVNNLNFQL-PHHTLLVDETSLQ-PAQLPRGTENCNTISNLLQWQSLEYDFEYH-NITFNTDLQVLITSSGKSMFPADCHVPLL-ERLRLYLSF-EQLESEVQNDFVAMRRVTQETLVVSRLLSLSYGQPQLTPACWQRAKELEQLRVAR Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin LVRFRCMIQDS-FEPEYFTGCRQVLFVSIPGEGQAAIFKVNEVYEFIGITNDEILDFLRTFGDELAAQSILFHLLSRVVGKLTDVIKQLVTLPMTLDNMNLQL-SDGSLLLDETSLK-PGSLSNGVKNIRAISTLVTTQKVDYDFQFY-QTPFYHDVNCVVLSEAKSMLPCDLHIKLL-NKFRIYLDMESHVMQEIENDFVSWRR---DDLVLARVQCASMGRSKCSSGDWGVVKKFDEKRKER CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 ------MVQDPSYGEELHFTEKEVAYVSVPGQHTAALPKASSVIDVVGI-RDMCLSHLTLGGDELAAQYLLLHLLSK-VGKFSDAIAQLVPLPFELGLLNLQL-APGTIICDETCLH-EGTLEHGVRNLHALQTSILEQTVTYLYPFQ-PIDISTNLRILVLSTGKSILQNDCDVYLT-EQIRQYLNIPKDVSDIISSEYADSRRMTQEDVTVARLISISKGQDVLDLASWREACTLEQYRKER Conco1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci QVQRRAI-------------------------HIGAQLRTTDL------AREKLVSWIALSGDRLAAD---------------DVLSHLVPLPLSLDAINLQL-PKGSCMVSELPLN-EGTVERGLLNLKQVQDMINHQTLDYVFPFS-RYSFETDINFIVLAAGKRFFTTHLQVPVL-NQFRKLVGLDSSTAAFIQDDFVKERQVTSDDMMVAKALAASLHSGEVTPQIWERAKVLENERQAR Croqu1 LVRFRCMIQDTGLGTELYLSERELVYVEIPGEHLGAVIRTASMLEVVGIVRERLVKYIAFDGDELAAQYLLCAMTSKILGALPDLLSNLLPVPLTIPALNLQL-ATSTVLLDALAMD-EGQLTMGLRNVACLARLVDEGKLEYSFPYS-QFLFDAQLPLLLLSLGSKFVDGFWTLPVL-ESWRMWLIIPQSLASEIQETFVSIRRMSQADLELARLVGLQFGRQEVSLEDWQWACKMEKMRKVR CryneH991 VVSFKCLLQDTGYPMEVYLKERWVGWVEVPGEYVGALFRPASTHEFIGLTREELLDYLANPPDRTAAEYLLLLLLSSPLGTLSAVISSISPLPLTIPLLHLQL-GDGTLVVEEDAMGDGGALEKALGNLKALVNCVKDQKVKYDYPYMDGLKMDCAVRVAVLSQGKSLLPVDVDIPLL-EAFRSYLVIPDETSQLIQDHFVQERK-----MKVARIVALSYPHATLNKDVWERTVRLDQEVVKR Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi LVKIRCMIQDI-FDPQFCTFDKTILYIPIPCEDENNLFKINEIIEFVGVIRNELIKFIKV--DELLSEYLLFHLISKVIGNFSLLYEILLAFSMSLENLNLQL-PKGTLILDETQLT-EGKVSQGIKVLNALNTLSIQQKVEYDFKYH-PIEIQTDLPTISISFGKSLIKGTTQISIL-NQFRNYITIAESATRHIQEDFVKSRQMTTDVLTLSRLVALSFNDQYIKIDKWNIMKSLEEKR--- Dmel LVRFRGMIQDM-MDPEIYHGERRTMFVSVPGLSMACMYQLNSLVDFVGFVHKDLRMLLKLFDDDLAAEYLLSHLISTVIGKFAQILELLLPMPMTLVTLNLQL-APHTLVLDETCMQ-QGKLANGVHAVQHLAHLINNQELKCDFQYY-QIDYQANIPVLVLSEGRSMLPSDFVLPIL-QQFRKYLNVSEEHTEMIQQDFVDMRK---DDLVLSRLLGIARGKDTLDKETWQLATEFEAKRRQR Enthi LNNLEEMIHNS----EYYISDRSLVSVTVIYESRGNLLKIGERYHLIGIVRNHILTLFN---------HLLLNLVSSILQKYSEVLHFFNP----VEVIDLQI-GNDSIITANKEINEQNKI---------IEELLNQQMLQFNI-YGQPINIPINCSVIFVTKRDYIRLCDHNIIIL-DAYR-YFSITEDVQDIVTNSFVNARKIDQMSLNVACILGSSYGKRKISHEIWNETLQLLSLN--- Falba LVRFRGFVQDT-LNTEFM--ERFPFFTAVPATATGSSLVLNGVVDFVGVLRAKLLHSLA----HLAAEYALLAMLA--QGRLSQLVQSLVPLRLDLQGLNLQL-PRGCLLLDETHLE-AGQLATGVGNLRLLHQLAAGSVVSYNYHYN-TIDIPTDVNVIILSEGRSIVPCDFAVSVL-PAARRLLEVPEDVVAGISQEFANERAASPDTLTIARYLAMSLGATHLSEDIWRRTKSLE------ Fomme1 LVRFRAMVQDTSCSPEMYLRERDVLWVNIPGEHIAIQLKPTNIHEFIGVIRDSLLNWMSFGGDHDAAEWILLSCLSSVLFPLSHVLSELLSLPLSLKLLNLQV-PSDTIVVTETGIA-EGSLQKGIENVQALQEVAKLQTLQYKFPFS-QYSFPTDIKFITVTEGKKFLDSNITIPIL-YSFRDYITVGEQLSEHIKNDFVRERQITPDDMMIARLISLSKLEGEMTMETWNAAKDLDARRQTR Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 MVVFNAMIQDTSLPPELYLRECSTFWVSIPGLHVGVQLRTTDILSFVGIIRKELIQWVALAGDCLLAEWVFLCALARVVLPLSHILSHIFPLPLTLDAINLQQ-PKGSLLLTEGGVT-EGGISKGVTNIRSAQQMMKDQTLEYAFPFS-DFQFETDVNFLITTEGRQFFKTDINIPLL-LLFRQLVVVNPELGKHVEEDFVRERSFTPDDMLVARLHALSLHQAEVKIDNWESAK--ELEKEAN Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 LIRFRSMIQNTGFGHEVFFSERQLFYTSVPGEHMAAILKVTDVVEFIGVIRSALIHYIAFGGDDLVAEFVLLQLLSRILGKFVSILASLLPLPLTLSTLNLQV-SQGTFLVDETVLK-EGKLDIGVRNLKALNDIMDHQKLNYMFPFN-NYEFNTDIGIIILSNAKTFLSYDCNIPLL-NQFRNYINIPEDISDYIQADYVAQRQMTQQDLNLSRFVGLSFGSLKLTKELWDYTKKLDEARRHR Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 LVRFRAMVQDTSLSTEMYLQECSVLWTSVPAEHELDQFKSTDIVTFIGITRRELIRWMALGGDLRAAEWVLFSCIARVLLPPSAVLAALLPLNLSLESLNLQL-PQGTMLVSEGGVR-EGQLEQGIMNVRALQEVMDAQTLAYVFPFS-QFSFPTDISCIIVTEGRKFFRTDFNIPLL-ATFRDLVQVPEATSEHIQAQFVLERQVTADDMTVSKLHALSLHEPTLSVETWQHAKALDDQRRAL Malgl1 --------------------------------NITALFKTSDVLDMIGLVRNALIRFLALDGDMLMAEYVLLALLGKVIGPFSETLRQLMPQPLSVGSLNLQL-APGTLILDETKMD-EGELEAGVKNIRALLSLLQYHTLPCVFPYS-EMDLPADLVFIILSQGK-ILPADVQVHSL-HAMRVYLSIPTHVSEQIQNDFVALRRFDQNDLSTARLLSLSHGCTELSADLWQMAKSLDLARASR Mellp23 LVRFRCMIQDTGLGKEIYLQERELIYVEIPGEHLGVLIKTHSAIEVVGIIRSRLIRYIAFNNDELAAEYLLCSIISNA---IPALLSKLLTVPFDIPTLNLQL-TSTTVILNSMNMN-EGTLSLGVKNIGCLKSLIEDRTLLYQFPFN-QFFLNLSLGFIVLSFESKFLEGFWNLPVI-QLWREYIKISDELSSKIQESFVNIRKLSLNELKLLKLIGTQLNTTELNWSNWEYVCKLEKVRKIR Mnele LVRHYVMVQDI-LDQEFYRDTRLVYYVPVPGRGVCCIFKINDVIEITGIVRSELVAMLRTAGDPIAAEYLLLHLLSHVLGKFATLFSSISEFPLTITNFNLQL-PKGMIILDETVLE-PGQLPNGVENLKCLGNLISWQKLAYDFGFSYNIEFECDAKVLILGEGKSLLPSDVVVPLL-NRFRKYLEVSDELQKKIEQDFVAERKVTGDTLVIARLYALSRGHTQLEEEDWNSAKSLERDRLSR Monbr LI-----------------------------------FKVHDLLEVYGI----------LGGDELAATYLLLNLISSVLGKFSPLLDHVLDLPLHVEYLNLQL-AAHTLTLDETLLE-QGQLENGVKNLLALQQVLQFQSVPYEFEHMSPMFFPCDIPVLIVSEAKSLLPVDIIVPVV-EAVRSFLEIPEAVQGEIERRFVQSRQVTGDVLSMAKLRAASFGRSTLSMEDFEAVQNMEAQREAR Morel2 LVRFKCMVQDTELSQEVAMDLRSSYYVSVPGQHFAAVIGVTDMIEVIGVIRDELIRYIAVRGDKFAAELVLLHLLARVLGKFSKVVKSVLPIPMTLANLNLQV-TRGTLLLDETAME-EGTLDQGIKNLKAVTDVSLYQTLNYVFPYN-NLEFQTDISLLIISFGSSLVPVDCGITLL-QSFRRYIKFSEDMAKEIEREFMEQRKITPNDISLARLVALSKGELTLNRECWDHAVSLSKQIKER Mucci2 LIRFRCMIQDTGLGQEMFIAERAIVYVSPPGEHASAIIKVGQLIEIIGIIRNQLISYISVGGDTLVAEYILLQLLSRVIGNFTDALQNLSILPLTIDGLNLQL-VDGTLLVDETVLD-EGQLDPGVRNFQALQNVIQNQTLTYEFPYS-QYDFDTDISVLSLSCTRSMLANHCTIPLL-DLFRRFIDISDQVSEYIQNSFVEERKPTQEEMNLARLAAASFGESNLTQERYDYVVDLDKKRKAR Mydma LVRFKAMVQDM-FDPEFYTLQRFTFCIPIPGLDQTVF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------VGKFSKFIQNIVPLTLEHKKLNLQL-SDGTLVVDETTMQ-EGKINTGVINISILSDLFQNQKITYDFNYH-TLDFPADINLIVLSEAKSLFPCDCIVPLL-NKIRGFIKIDQEMANDISKEFVEKRALGQDDLNLARLYTLSHGQTHLTNEFWINTKELEEKRQNR Pench1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 LVRFRCMVQDTGLGQEMFLSERTNVYVSPPGEHVSALLRVGQLIEVIGVIRAKLVDYIAFGGDKLVAEYVVLQLLSRVLGQFSFILSNLTQMPLSLEILNLQL-PNDTLLVDETVLS-EGTLDTGVRNIQALMNVIHTQSLNYMFPYS-QFELDTNLGVISLSSTKSMLPNHCTVPLL-DMFRAYIEIPDDVSEYIQEEFVNERKPSQEDMSISRLVALSFGERYLTKDTFNYAVSLDEQRKGR Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 LVRFRAMVQDTSPSPEMYLRECTVLWVSVPGEHLGVRIKSTEVYTFVGIVRVDLINWIALGGDRDAAEWALLVAISRIIFPPSHVLEEILPLPLSLDLLNLQV-PSGSYLVTESGIQ-EGKLEKGIMNVRAMQEVMTNQSLAYIFPFS-QFSFPTDSTFIVLAEGKKFFQTNITLPLL-ASFRALVQMGEDASKYVQEDFVKERQVTADDMTIARLLALSSHEKEISIDTWERMKTLDARRKAR Polpo LVRIRCMIQDV-FDPQFYTFERNQFYIPVPCE-----LRVNEIVEFVGIIRTKLISYLLLLGDSIAAEYLLCHLLSKVLGNFPRFMSSVVCLRVTVENLNLQL-PKNTVIVDETCLN-E---QQ----------LQQQQDIQLD--------------------DSSLI----------NQFREYVTMSSSVTKHIEDDFVSTRQTSQEILTLARLLTISYGEQEISIERWNYMKNLESTREQQ Pucgr2 LVRFRCMIQDTGLGPELYLSERELYYVEIPGEHVGALIKTSDVIEVIGIIIDRLLNYLSFKGDDLAAQYLLASIAAKIIGALPEVLSSILPIPLTIVSLNLQL-SPDTLVIDSRKMS-EGQLSMGIKNISALKKVVNDGKLMYSFPYS-TFEFDVEIGIVTLSEGCKFLEGFWPLPIL-SIWRGLIIIPESLSSEIQEAFVSIRKMSQEDLQLARLLGLRLGKDEVDLDDWQQACKLEKLRKIR Punst1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ------MIQDTGLGQEMLLLERTLVYVSPPGEHTSAIIRVGQLVEVIGILRYDLVEYIALGGDKLAAEFVLLQLLSRVIGHLTDVLENLTVLPLTIQGLNLQL-VDGTLLVDETVLD-EGQLDAGVRNFQALQTLIQTQTLGYEFPYS-QYDFDTDISVLSISSNKSILPNHCSVLLL-EQFRRFIDIPEQVSEYIQESFVNERKPTQEEMSLARLAAVSFGENTLSKERYDYVVELDNQRKLR Rhoto1 LVRFRAMVQDTGMGSELYLKERQLFYVSVPGEHFGLVLKTTVVCEFVGVLRKELVAYLALGGDSDAAEWVLLALVARILGSLSQTLASLVPLDLSIASLNLQL-ASGTVVVDLRGIG-EGKLDTGVRNLRHVATTVAQQKLSYEFPFS-SFELETDLNFILLSEGK-IVPAECVVYVL-DQFRSFIDIPEGMSEVIQSDFVARRQMSQDDMTAARLMALSYGEKELSREAWMRTAELDDRRKER Rozal11 LFRFRALVVHDSYDNEVFWMERKVVQISIPNVYDGSVVAVCNAYEFLGFVRNTLLSTISLRGDALLSELILYHLFSKLLGQLNPLLQLLLPLSLDLNVLNLLL-TKGTLIVDETKLN-QGELEQGIRNLALLKDLIQHQTVMFNF----PITISTDIPIIVVSEAKSMFSMEQSIQWMINTIRVFIEWDHDVKKKMEDFFVEKRRYSAQDLELFRLMSMSYGQSEFVDEIWQECDLFYRKWQQL Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro LVRFRGMIQAT-HNPEIYYKSRHTLHVPIPAERTPALVKLHEMVEVIGVARPPLHRALLVGGDDLTATLLLLHLISRVLGQFPAFLSTITTLDMSLRSLNLQL-PRHAVILNETAME-AGQLERGIANLMALKTAMDTQQVAFEFEHAGSIMFDIDVQLLVLSEGKSMLPVSTKVPIT-DAIRAYLTIAEEMQEAISSDFSTMRQITADALGIARLVSLSYGRSSLDLDGWTEAKRIDAAVTQR Schco3 LVTFRGMIQDTLPPTEMYLKECNVMWVSVPGRHVGLQLKSTVVHDFVGITRTELIAWLALGGDRFAAEYVLLCAIARVILPPSPALALIFPIPLTLPTINLQL-PRRTCLLTESGLTAEGGVERGLRNLHATQNMMKNQMLDYEFPFS-SFGFETDVSFVVVAEGRKFFETSVNVPLL-EAFRALVKVGEEAAEYIENDFVKERQMTADDMQLARLLALSYHEPEVTIDIWKKTRALELERKAR Schpo1 LLRLQGMVQDTNFGHEFFLDERYSLFTNVPGEDTGVCVQVCQAIDVIGIIRPKILKYFE--GENIAAESLMLALLSNVIGGFTSVLRPLIKQKVNVAELNLQV-APGTIVLDETELS-SGTLDVGCRNVQFLSSLISQQDLTFFYPFS-SFTVHSNVRIIILSHGRSILPADVGCRCL-QEFCNFFNIPENMLDYIQSTYVSSRQINEKTINCSRLYAKSFGRQLVSRIDFEAARSLINHWTVN Sorma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar LVRMRGMVHHT-FDRRYCFIAQTEVYTPIPGQ-GAAVINTH--VDVYGIARATIIEILSLCGDVAAAEYVLMHLLSSTVGKVSDILRSLTPIPLVMDTLNLQVAPRITFLIDEVALQ-TGKLDTGVKNLQAIQNLLVSGVVPYQFE-TYEMRFECDATTLVLSEGKSMLASELPYKLI-DQLRTYVTIDDATREKCISDYVELRKVTPETLTLARYCTISFGKSLLSADIWVKVQRGENERNGR Spipu1 LVRFRCMVQDNSFNVQEYVAEKQPVFVSVPGEAVGAMFHLNDVLDVVGVLRTRLLEHFCLFGDRLAAEYLLLHLLSKIIGYLPQLVSSLVPIALTLKHLNLQL-ADGTILVDEMTLE-DGILERGVRNVAHLGEVIRTAKLPYIIRYG-EMKRNVDYNFLVISQGRCMFAIDCIIPLLKNDARIFLQVPSDMVELIGRQYAEQRATTNLDLEVARLVTKSFGRSSLDVECWDHAGMLESERMAR Sporo1 LVRFRAMVQDTGYGTELYLKERQVSYVSPPGEHFGMILRSTDVYEFVGVIRHDLIDYIALGGDVEAAEWVLLALIARILGSLSQLLSSLVPLSPTIASLNLQL-PKSTVIVDLIQFG-E-----GVRNLRSLSTTISQQKLAYEFPYS-SFELDTDLGFIVVSEGK-IVPTDCVVYVL-NRFRSFLSIPPQMSDVIQADFVERRQMTQEDMTVSRLMALSYGKRELDESSWMKTAELDERRKER Stehi1 LVRFRCMVQDTSPSPEMYLRDCSVVWVSVPGEHVGVQ-KTCDILNFVGIVLDELVSWVALGGDKDAAEWILLASTARVLLPPSHILSLLLPVPLSLELLNLQV-SDGTLLITESGVR-EGKLERGVLNVMAVQNVMLSQSLPYKFPFS-EFSFPTDLSFIVLAEGKKFLKTDINVPLM-RAFRSLLEVAGSTSERIQDDFVEGRKLSSDDITTARLLGLLRGEKELSIDTWTRAKALEERRKAR Tapde11 LVRCTCHVVHT--DSEIYFEERTSLRIHVPAT-----LVIIGILEVVGAVRADLLHRLELEGDALAAELCLLSLISGVIGPLTSLVSDLT-FDMSIDNLNLQL-PADFVILNESALS-EGKLERGVKNLQCLSNTITSQDLKFQFPFS-EFKIPVDLSFITLSHGKSLLPSTISVPLI-SQMRHYLEIQEEVSKEVQEDFVNSRKMDQADLALGKEIAKSYSRRQMTWDDYTKAKSLRKRILSR Thetr VVRFRCMVQDN-LDT-LLYSDQYTYHTTVPGESAAAALKLNSIIDVVGILPLSVEAALGAGGDALAAEYLMLALVSRVLGSFHQAICDVAPVPLAIDLLNLQL-APSTLLVDETAMA-SGQVQVGVANLFAFATIMDRAALEYDFAYD-NITVAMDTPVVVFSEGTSM----FASSKI----RRFLTFDDSLSDAISDEFTTLRTMDPQRLTLARWHALLHGKSSLDMDSWAAVKDMERARLAR Treme1 VVSFNCLLQDTGYPLEVFLKERWIGWVQIPGQYVGALHKPGSVEEYVGITRTELIRSLGQPRDDVAGELLLLFFLSYPIGTLAMVTRLLMPLPLTLPLLHLQL-APGTLVLDEDGMGEGGQLDKAVKNLQALAQCISEQTLRYEYPYMENLKMECAIRPLIFSQGRSLLPVDICLPVL-QRYRSFLEIPDAISAYIQEGYVVDRR-----ADMIRLLALSHEPPILSRDVWERAIALDTQVLAR Trire2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 LVRFRCMVQDSNLGPEIFLDERSVLYVSPPGEHSDAVIEVGSRIEVIGILRAQLLEYLGFGGDVMVAEYVLLQLLSRVLGQFSSILQKLLPLPLSLDVLNLQL-LDGTVLVDETMLK-EGTLEQGVKNMRALNKVIQQQVLGYAYPFH-EFDLSTDIGFIVLSRAKSMFPCHCVVPLL-SSFRKYIDIPQAVSEHIQERFVETRKPTQDDLNLARLVALSFGSNELTQEFFDYTINLEKMRVSR Ustma22 LVRFRAMIQDTGLGTEVFLAERTVMYVSLPGQHVGGLFKTTELIEVVGIQRQALIDFLALGGDKVAAELVLLAVIARILGALTLRLKQLLPVSMDLGALNLQL-VNGTILVNEGAMG-EGQLDTGIHNIKALSSVLESYKLPYAFPYS-EFEFDTDLNAVILSQGK-FLPFDVQCPLL-WTWRKALVIPESVSEHIQQEFVAERRLGQEDMSIVRLLALSYGEKSLSIETWSKAVELDKLLAQR Walse1 ------MVQDTGYGTEMYIRERTNIYVEIPGNKLGVLLRPATVYEFVGIVGEHIITWLALGGDKLAAHYLLLSLVSKTIGTLPKAIEALTNLALSIDKLNLQV-SPSTLIFDERHLG-QGTLDTGVRNVHSIQNVIQSQKLEYNFPFS-AFPFETDLITVILTDHSKIPGT-IHINVI-KLWKEFITIPDEVSSIIQQSFVDERQTSSDDITMARLLT-SLDDGEMNNDHWNLITKLEKEREER Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3485.fasta_al_trimmed; alignment length = 293] Allma1 MLTPQFSVTQTDADVTLRIRAPHVRATNVETLV-AGPNFRFHCKPYFLSVYFIQAKYDIDAGFTITIPKKVPGTTFDDLDVLPQLLVPPGIHEVTWDQHLNELRGVFPEVLDVSPADRRIEREDGDFNEDHYMENFVD-IQSLLKCAEFT--QAEQDALVQ-RSTRKMLSLLALIDVVLSYALAVRLEAGDNPEASWMVSKVCATLSGMETSLHAVLTTRRALCYPLYRHRALARRADTHTILRGGRRAIRALLAVHHVLAFVFNTVWIDPLLNWVIMAAVANEGLEQWEALA Ashgo11 MLTPKFKLTQDEEYIYVDISISSIRASGLELVV-DDTLFVFHLSPYYLRLRFCKAEYKAADEIFIKIPKLNKGEVFEDLDLPTKLLARHLIQEIEIKQV-NQYDSVINDINELGPNERRIRKENLKFDPEYYISEYMNGIKSLLQYVEFS--PKEDELMRNLPKKSYLILYVAILSLLFAHTFEQVENEGINTESAWTIGKLTPQIACLDPVVRAAVVARRALAYPLHRNFDLVCKCYVYYLLRAGKRILRALLDIYELYRYVYNKVFLGDLCSWFVTRSLAFELLAEMELLA Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 MITPRFTCDQTPDSLVVVLHVPAVRARDVEVHA-ADTTLSVHVNPYFLRLVFSSARYDPSSGLTVTVSKQVKGEHFKDLDLLPKLLAPELIEVLQLPQEVDLHSGFFNDVNVLPASARLVEADEKKWDEEYYMMDYVEEIKAVIEWEEFS--EDENLAQLRLPRREYLILHVTLASILFSYFYDARATGHDTTESAWTISALTPCFVAL-GTLQEAMVARRALCYPLYRSWALCERVDVAAVLACGQKVLRVLLEANAILAYVYGKIWVEDYCVWVSLSAASAEVLEELELAA Batde5 MLTPRFTVTQTNDFVELVLQCPFIKAQEVEIDI-DGSEFKFFAHPYYLRLSMEQSKYDIDKGVLLKIPKEQPGVYFEDLDMLTKLMGIKSIQTISYPQQLNQYSGFANEILDVTPESRRIDSENAKFDEDYYISEFLDEFVHLIKYREFT--ELEQSQLRNLSNRQYLIIYLGLVDIIFGYCFNLRTTEGETVESAWTICKLSGTLSCFDLSLSEVVSCRRSLAFPLNRHIDLTKIVDVVILLKLGRRILKALLHIKRLLEFVLDRVWITDYCVWIQLKSLASELLKELEELA Botbo1 MITPRFSCTQDDASVTITCYVPSLRAVDVEIDV-DGPSFTLHINPYFLRLTLSSANCDISSGLTIRLTKETRGEVFADLDLLAKLLAPTLIEVIRLPQTVDMHTGYFNDVNLLTDEERREKQEDEKWDAEYYLADFVEEIRELIRWREFT--EEENLTMLRLPRKEYLILHFTLLTILFSYAYDLRTTQHDTTESPWTISILTPCFSALDSSLTSCFRARRALAFPLYRNWALCEKLDVANILKGGKRVLRALLEAKKIVDYVYSKIWLDDYCVWVQLVSLAREVLMKVEMSA Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel MLTPVFWITQDDDALLIRIRAPHGNIAELDYDH-GDYMFVFTCPPYFLRLHFGSVEWKSDEGFHIKVPKMHKKEHFSNLDMITELLTPSLVEEMQQPAAEWSKFGVIGKIVDIEIEKRLMEFDWENFDEGRYLADTLEELLAVISSKEIS--DEDRTKLKDLKKSKTSAIMTSLIDIVFGYCYDQRVNDWEACESGWNCAKLSPSLSFFASSVKECLLARRALTYPLYRSFQLTQRVDVCHVIGGGRPLLHILCDLHRIFIYILNDLMIADYIFWIQLTRIQTDLLEVLEAEA Canalb1 MITPFFTISQDDEFIYIDVKISHIRAPNIEMTV-ENELFVFSLPPYYLRLRFSHAEYDSKTEVKIKIPKETKGQFFPDLDLTAKLLARTLIEELEVKQDVNQYDNIVNDINELPENARRLIKENIKFDPEMYAADYIKNFKELIDWKEFS--KEEQEKMMNLPRKSYLIILLTTICLLFAYHFDLRENEGDNIESAWTIGKIVPQFSFLDNVLRAAIITRRALTYPYHRNFDMITKVDVYYNLRGGKRVLKALLDLKELFRYVYDKIWLEDLCAYLIIRNLAHDILPEIEVMA Cangl MITPKFEVSQDDDFVYVNIKITNIRSGGLEVVV-DKTMLFFYLSPYYLRLRFTEAQYRSKDEIFIKLPKAVKGQYFDDLDIPTKLLARQLIQEIEIKQNVAQYNGLINDINELTENDRRLSKENLKFDPDYYVSEYMNGIKKLLGFTEFT--EFEQNQMVNIPKKEYLVLYLTIVNVVFAYIYDSIENEDANSESAWNIGKLTPQIAFLDSIIKVLIYTRRALSYPLHRNYDLCNKAYTYYILRGGKKVLRALLKVHEIFRYVYNKILLDDLVSWFILRGLTMEFIKEMEILA Capow MLTPTFDLTQNAEFLFVRIRVPHVKIGDVEYFV-DGHLFKFFVRPYFLRLNLEFAQYDLDKGILIQLPKRTHGEDFPDLDLLTALLAAPSSYDISWPQKPLRHSDFFVELIELPAAQRRLAAEDADFDEHHYVADYAGVIPSLIEYEVVL--TAEEKDILRFRLKPHLLLYAGLVDILCAFVYDLRVTEGENVESTWTIWKLSPSLSWLDDTVSDAAIARRSLCYPLYRHFALSKKIDVARLLRIGKRVLRCLLVVQQKFSYLLCNIFLDDYCLWLQLARTADELLKLLEDAA Catan2 MLTPLFSVTQTADHLVLRIKCPHVRATHLETRI-DGPNFRFHCKPYFLSLAFHHANYDIASGFELTLAKLEPGTHFQDLDILPSLLSGPVIEELSWPQTLSHFSKFFHELLDITVTERREIAEDTKFDEDHYIGVVIETITELIRYEELT--DDEQSRLVRSAAKRPILLLLATLDLVATYAFMHRHDMGDSVEHAWASSRVSATLSCLETSPMHVARSRRSLAYPLYRSRPLIRKTDVPKIIAGGRRVLRALLELHKSFEWIWNTLWVEPLVHWVT-AGVFED-LEAWEEMA Cioin MLTPKFQINQDDVSVTIVVHAPYTKVSEVDIFI-EETCFAFHAKPYYLRLELSSCKYEVDKGYTVHVCKQEKGEHFENLDLLTTMLAQKLIEVVEHEASLNQKHGVICDIVYISLEDRKQAAEDLKFDSDYYLADLYDYIQHIIKFIEFT--DEEKEQLQKLPNKEYLIILNGLFDILFAYAYNVRVTEGECVESAWNIRTISHTLSWCCSCLKETVVSRRSLCYPQYRNWKLGCKVDVIRILKKGRRILHCLLHIWRIFQYILNDLYITDYCVWLQMKSLSKEALELIEEAA CocheC53 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 MITPRFEVRQDEANVYVTIHAPHIRAQSIEFDV-DVDQLKFFASPYYLRLTFSSATYDATLGILVTLSKQTPGEEFPNLDLLTGLLATRIIEEIEFPQKPSQYSGYLNEVNEVTSEARRISFEDKKFDNEYYIDNYIDDVQPLIQHTKFT--DAEKKQMINLPRKTHLIVYLGLVDILFAYLLELRINAGENVESVWAIGAVSSTLSNLESTLRSVAVARRGLAYPLYRNWELCEKTDVYTVCSLGCRILKIFLELKRLFDYIYSKLYFDDYCIWLQVQSLARKLLNEYEDLA Conco1 MINPKFSIEQEADFITLKIYTPYIKAQNAEFLI-DGAQIRFLLNPYFLRLTLSQAKYDLATGFTVQLYKVNPGEHFKDLDMLSKLLATQLIEELELPQQINQYSGYFNEINEIAPLDRRIQKENEKFDEDYYMSDFMEEFQQILNYRQFN--DKEKEIMRKLPKKSYLILYLGLVDLMYCYSYNLRTNFGETVESTWIIGKLSPTLSSLEQSLKHCVVSRRSLCYPLYRNFKLCEVLDVYKIFKLGQRILKILLELKDLFDYRYSKLFFDDYCNWVQLKSLAHQLLEEWENLA Conpu1 MITPRFSCTQNDTSVIVKVYCPSIRASEVEINV-DGQLVVLHVQPYFLRLNFSNAQYDPTSALTLTLTKESSGQFFEDLDLLSRLLAPRVIEVLQLPQTADLYTGYFNEVNELPLEDRRLQHEEDKWDEEHYMADFATFIQELLSWQSFS--DEENMILLRLPRKECMLIYYNLAALLFAYAYDNRTTMHDTPESAWTICSLIPAFSALDTELAATLTQRRSLAFPLYRSFSLAEACDIAGILSKGKRAIHRLLEMKHTLDYIYSKIWIDDYCVWLQLQEMAAALLLELEAAT Copci MITPRFSCSQTETAVVVSMYCPSIRAADVEINI-DETLLTVHVNPYYLRLNFSSAQYDPSSGLTVTLTKEQKGQHFEDLDLLAKLLAPRTIEVLQIPQQVDMHSGYLNEINELPKDERRIEREEAKWDPEYYMADFAENIQELLHWKEYT--ESENLEILRLPRKEYLALYLTLVTLLYAYAYESRTNQLDTPESAWTICSLTPAFSALDNELITTLVPRRALAYPLYRSFALADKCDTAQLLLKGKRVMRCLLDMKRILDYVYSKIWVDDFCVWVQLLELGNCVLEELEAAT Croqu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 MITPFFTINQDDEFIFIDVKISHVRSQNIEMMV-DNELFIFSLSPYYLRIRLSHAQFDSKSEVKIKIPKLNKGEFFPDLDLSSKLLARSLIQELEVAQ--NEYDSIVNDINELPASDRRLIKENIKFDPEYYAADYIKLFTDLIEWKEFS--KDEQEKMLNLPRKTYLILLGLLVSLLFAYHFDLRETVGDTIESAWTVGKLTPQFACLDNFLKSIAITRRALSFPLHRNYKLVSRVDVYYNLRGGKRVLKSLLDLKELFRYVYDKIWLEDLCSWIIIRNLAHDLIQEVEIMA Dekbr2 MLTPRFSVDQNDEFVFVNIKLSSIRARNVEIVI-DDNLFIFSLPPYYLRLRFVKSSFVPKEEIKIQIPKKTTGEHFDDLDLTAKLLARLLIEEVEVEQKPNVYSDMINDINELKPDDRRLIQENLKFDPEYYASDYLCRIKDILGWQEFD--QAEKDHMADLPRKSYLVIYYTIVCLLFAYCYEIRSNEGDTVESGWSIGKLTPQLSCLDSMLRVVVLTRRALSYPLVRNYELVKDCDVYYVLRCGKRVLKAILAAREFFRYIYCKILLDDLCSWILLRNLAHALIDEIEQLA Dicdi MIIPKFSVDQNDEFIIVVAITPYIKASEADFYL-LENQFKFYCKPYFLRLTFEKASFNVNTQFTFYLPKEINGQKFNDLDLITKLLEKKKIQVLEFEQIVDGYSDFFSDIIDITKQERRTEFEDLKFDPERFMENHFDDIKELLHYKTFS--DEEKDIMKNLPNKEYMIILLGLVDIIYSYAYNERVNMGYNIESAWNICKLSGTLSCLDYNLSSVLECKRSLTFPLYRSWLLSERVDTKQIFQLGKRLLKCLLDIKKKLEYYLNRLYIDDYCIWLQLKSLRNKLLEEYEKLV Dmel MLNGQIAHSYLENSCTLIIPRPPVLAHDLYFYA-DVKLYKFHSRRTFLLIKFAAKQWNSRKEIAA----------FLHLPTLSANLPDKLVQ--KLKRITSEYSG--LDLSELSPIQRRVVDEMKRFSREQYKINFVSGHQNPLRYKETS-MTQEQAHLLHISRMQTREIDCGLISILLAICYDVRTTNNETCESGWTRSILCPLYCYFEDNYRDVLVARRMITYPLYRNFELGRQCDAIEVLKGGRNLINQLLLTHQQFADSFNNYYLEDYIRYVTMRLLARNLMRLIENEI Enthi MITPYFSLTQNNDYVIVHIKIPPYQVEDIQI---DNNTMIYHSEPYFLSLTFEKAEIDRLECLHVYLPKENKGEVFPDLDMLPLFLTKKVIKEIGEDQQIGSHSEFFFEIVMLDSKGRRIDDELNSFDKDRYICDTFDNEEEVLKNNDWT--DEERNEFGALDKIEVLVIYKDLFGIVYGYLYD-QIVMGETVESGWTIATLSPVMSYFDDDIVDLIETRRSLIYPVVRNWELSMKTETIEVFKKRRVLMKILLRIHQIYKHYMNYLFFDEYCNWIQRHQFVVRILQDAEQEY Falba MITPDFDVTQSETHLHLRAHTPHLSPNGIDIAV-AEDSLRVHARPYFLRLYLWRVSYDIGSGLDVVVPKANPGEWFDGLDMQSRLLATRAVEVVELDQAEDRLNPFFLPVRALVAGRRRRLAEAAKFCPEHYASDFAGLVAESLAFRQFGYSARESKQLRELPR-----TLLGLIDLLFCYSYNLRVCQGETVESAWTCVHVSPMLAGLEATPREVLLGRRALAFPFLRHWDLAARADVVTLLQLGRPVLRALLALLYMLEGPLARVWLRDYCLWIQLAGMADSLVQEIEDYV Fomme1 MITPRFSCSQTADAVTIRIHAPAIRASDVEIHV-DETLFSVHINPYFLRLAFSSAVYDPTSGLTVSLTKAMPGEHFKDLDVLAKLLAPPIIEVIHLPQQVDAYTGYFNEVNELSLEERRVKHEDEKWDEEYYMADYVENIREHIVYKVFT--EQENMEMLRLPRKEYLALYLTLLTILFSYAYDARTTQSDTPESAWTICSLTPAFSALDRDLQDALIPRRSLAFPLYRSFALAEKCDVSVVLQHGRRVLRTLLETKRILDYVYSKIWVDDFCQWVALKALGQTLIPALEAAA Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 MITPRFSCSQTEDTIIVSIYCPSVRAAEVDINV-DETLVAVHVNPYFLRLNFSSAQYDPSSGLTVTLTKENRGEVFEDLDLLAKLLAPRSIEVLQLPQEVDMYSGYLNEINELSNERRRVKHEDEKFDEEHYMADFMEYIQELIAWAQYS--EKENMTMLRLPRKEYLALYLTLISLLFSYVYESRTSQCDTPESAWTMGILTPAFTALDDGLEEVLVPRRSLTFPLYRSFALAEKCDVAGLLRKGKRVIRCLLEMKDIFDHIYSKIWLDDFCVWIQLELLGMTLLEKIEKVA Ganpr1 MLQPKFRLSQDAHAVTLVLHVPFIRTQEIELDVSDGNIIRFHAKPYFLRIHLHTANYDIGSGLTVRIPKECPGEDFKDLDLLTKLLVSPAIEVLSFPQSVSAYAGVGFEVVECPKDKRRREMEDASFDEDHYIADLAQDIAHIFEWN-FT--EKENRALTLLPKKEYILTYLSLIDILFAYCYDLRTTEGETVESAWTICKISSTLCWDAPSLPSLLATRRSLAYPLYRSWRLSLLVDVRSVLKLGKRVLKCLLDMKEVMDYLVGRLWVDDYCVWVQLRSLYDDVLNDLDEIA Gloin1 MITPNFTITQDFKFITIIIKTPYIKVSDVELYC-EGPDFSFYVKPYYLRLHFVNASYDISSGMNIKIPKETPGEEFSDLDLLTKLLAPKLIEIIELPQQIKLYSGYFNEIIDITPESRRINAENSKFDPDHYIADFMEEIKNLIKSKNFT--EEENTIMRNLTNKQYLIIYYGLIDLLFAYSYNYRVFEGETVESPWMIGKISPTISCLENSIEETMKARRSLAYPWYRNYKLAKKCDVYDLLKLGKRILKVLLELKDLFDYVYSKIWLDDYCIWCQIRSLAHKLLEEYEHLA Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 MITPRFTVTQDDEYIYVQIKVSSIRSAGVEVVI-DGCMFIFHLSPYYLRLRLNTVEYDSKQEINCKILKAVKGKEFKDLDLASKLLAAKLIQEIEIKQEVNLYTGYINDINELSPENRRLKKENLKFDPEYYAAEYINGIKRLLGYLEFT--EAEQTQMQDIPKKKYLIQYLTILSILYSYTFEQIENEGQTTESQWTIGKLTPQISMLDSQIKGTIVTRRALSYPLHRNYDLCIKALAIKLLLGGKRVIKALLDIHELFRYVYNKILLDDLCAWFIIQSLALQAISEIEYLA Lacbi2 MITPRFSCSQTDTAVIVSMYCPSIRAADVEINV-DEMTLTVHVKPYFLRLNFSSAQYDPSSGLTITMTKENKGQDFKDLDLLAKLLAPRVIEVLQLPQQANMHHGYLNEVNELTVDERRIDHEDEKWDDEHYMADYMEYIQELLDWTEYT--EKENAEMLRLPRKEYIALYLTLVTILYSYAYDARTTQLDTPESAWTMCALTSAFSALDEEVTAAIIPRRSLAFPLYRSFYLVDKCDVADFLAKGRRVMRCLLRMKDILDYVYSKIWLDDFCLWISLEKLGKVLLEELETAA Lenti61 MITPRFSCSQTDKSVIISIYCPSVRASDVEINV-DETLLTVHISPYFLRLNFSSAVYDPSTGLTVTLTKEVPGQDFKDLDLLAKLLAPRTIEVLQLPQAVDMHSGYFNEVNELPPDQRRIEHEEEKWDEEHYMADFAEYIRELIAWSEYT--EKENLVMLRLPRKEYLPLYLTLLTLLFSYAYETRTTQHDTPESAWTLASLIPAFSALDDELGATFTARRALAFPLYRSFALAEACDVAALLARGKRVARCLLEAKDILDYVYSKIWVDDFCVWVLLARLAESVLEELEVLT Malgl1 -----------MAHMEFDAR----------RSV-E-HPYGLGYERIPLP-------------------------------------------------RV---------FVDVSLSERAENLESEKWDEGMYLDSYFGEVAGVVRVE--------------LPHTMGATSQALLIQVLFAYLYEMHVSLNDSSESAWTICKLCRSIACFATMAEYVLHARRALTYPLYRSWALC-AQDLYSLLDAKARVLRDMDAIFALAPQLIWDVWFAPLEVWVQIRALASTILDTLEWAA Mellp23 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele MLTPKFSLTQTEQFVIATLHVPHVKISESEMFI-EGTEFKFYLKPYYLRLNFEHAQYDIEKGIIVHIPKKNSGENFTDLTMINKLLAPKKIEVVEWNQEYNKYKNYYPELLDLPLSNRLELNLMESFDMEHYLSDYMEFVGDVIHYQQFSCVEDEQQLLCQLPHFQVHITLVGLVDILFAFVFDHLTNCGESVESPWNICKISSQLSWLYSSLKECLLLSRALTFPLYRHFDFCSRVDLKFIVSKGKPILKCLLGVYDVLRYLHNNVFLKDYCLWIQLKKLNDALLEEFEAFL Monbr MLTPEFELQQDDGHVLLTIRAPYVKANDVDWLI-DGNVFRFHIKPYFLRLCFEQVAYDINTGFTFKLPKETPGEHFEGLDLHNLLLRSTSIEVLEVEQELAKHTDVVPELTRLDNDQRRVDAEEADFDEDYYWAECEQLIVPLLRAPPLP--KAYRVRLEGLPKRELLPLLVNILDLLLTYCYEYRIWGGDTPESVRTMAQLSSTLSHLQTHAKDVLQARRALCYPLRRHWVLVVATDVQTLFAAGKRLVMVLLDMKALFDYPFVDLFLVDAILWLLVATLAEFLLPAAESES Morel2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 MITPTFKVDQDNDAVHITINTPYVRAQDVDLYV-EGSEFRFYLRPYFLRLHFSKAVYDPSAGFNIRVTKETKGEHFADLDLLTKLLARTLIEVVELPQEVNQYSGYFNEINEVTVESRRIASENTHFDEDHYCMDYVEEIKELCKYKKFS--SKEEAVMRDLPNKEYLLTYLGLVDLMFAYSYNHRITEGDNVESVWCIGRISPTLSSLETVLKDVLISRRALTYPLYRNLSLCEKVDVYILFKLGKRILKALLDMKHLFDYVYSKIFLDDYCVWIQLRTLAHELLEELEDIA Mydma MLTPSFELRQNNDFLILTIKAPYVKANEVEIYI-DEYDFKFYVKPYFLRLTFENASYDIHKGFTINIPKLQSGEFFPNLEMLTLLLANKLVEVLEIEQTLNKYYGLFSEVIDLTPSDRRKLADAEKFDKDHYIADFLELMKPLLEFCEFT--EDEKYQLMQLAQNDHILCFLSLVDILLSYCYDIRTTEAETTCSAWTISKLSSTLSWLEKSLKDVLVSSRCLCYPLYRNWDLFVKVDAKNLFLHGKSILRCLLDIKRIFQYLLNELYINDYCVWIQITSLATNILREIEKEA Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 MITPTFKVEQDDNSITIIINTPYVRAQDVDLHV-SGTEFRFFLRPYFLRLYLSKAVYDPSLGFTVKVSKENKGEHFPDLDLLTKLLARRLIEVIELPQELNQYSGYFNEIIDITIESRRLEQEELKFDEDYYAMDFVEEIQNAIKYKKFT--PKEEALMRSLPNKEYLLTYLGLVDLLFAYSYNHRVSEGDTVESVWCVGKLSPTISCLETTLKDTIIARRVLSYPLYRNLALCEKVDVYVLFRLGKRILKALLDMKDLFDYVYSKIWLDDYCVWIQIRTLAHELLSELEEIA Picst3 MITPFFSIRQDDEFVYIDVKISHVRAQGIEMIV-DNELFIFSLSPYYLRLRLSHAEYNLKDEVNIKIPKETKGQFFPDLDLTTKLLARTLIEELEISQEANQYNAIVNDINELPATDRRLIKENIKFDPEFYAADYIKSFKELLEWKQFS--KEEQEKMINLPRKSYLVLYTLLVSLLFSYHFDLRETEGENIESAWTIGRLTPQIAYLDSILRAAVITRRALSYPLHRNYNLTVKVDVYYNLRGGKRVLKALLDLKELFRYVYDKIWLEDFCSWLILRTLAHDLLHDIEVMA Plicr1 MITPRFSCTQTAQSILVAIYCPAIRASEVEIHV-DDTLFTLHINPYFLRLNFSSAKYDAESGLNVTLTKEVPGQEFKDLDLLAKLLAPRIIEVVQLPQEVDMHSGYFNEVNELPLAERRVKHEDSKWDEEHYMADYAEYIQELIAWREYT--EEEKLAMLRLPRKEYLALYLTLLTLLFAYAYETRTTQGDTPESAWTLSTLVPAFSALDASLGATLVPRRSLAFPLYRSFALAEACDVADILTGGQRVVRCLLAMKKILDYVYSKVWVDDFCVWAQLTQLGVSLLEALEAAT Polpo MIVPRFTVEQNNDFIIVVARTPYIKANEADFYL-MDTVFKFYCKPYFLRLTFEKASYNLDTQFTFLLPKAVSGQYFSDLDMITKLLDKKKIEVLEFEQKLNKYVGFFTEIIDITKEERRTELENLKFDPDRYMENYYENVEELLHYKTFT--DEERDIMKNLPNKEYLVLLMGLVDLMFAYAYNVRSNYGDNIESAWTITKVSPTLSSL-----------------------------------LGKRLLKCLLAIRKSLEYYLNRLYIDDYCVWLQLKSLTKNLLEAYEKLV Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 MITPTFKVDQDEEFIYVTINTPHVRAQDVDLYV-EGSEFRFYLRPYFLRLHLSQSTYDPSAGFRIKITKETKGQVFPDLDLLTKLLARKLIEVVEIPQELQQYTGYFNEINDITAESRRIRLENERFDEDHYCTDFAEEIQYAIKYKQFT--AQEEEMMRQLPRKEYLIIYLGLVDLLFAYSYNHRLTEGENVESAWCIGKLSSTLSCLE-----------------------------------------------------------------------ASER-------- Rhoto1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 MLTPKFELSQTADELELVLECKSIKTLEIQIHI-NGKDLKVFAMPYYLHLIFQITPFDEETGIGMKFLKNVSGEDFGDLRDIKAIEIDILLNEVDLPNKKKKYSGILNEIIEFSLEEKQRKNEDEQFDPNYYIADQFPRIEELLSFQLFS--NEEKELLNDFFKLSIIVVLYGLVDILYAFLYELRVTEEDNVESTWTITKISSTISCLSKCLKDVLVSRRSLTYPLYRNWDLCNQVDLQKLLNLGKRVLKALIKAKTLFEFLVNELFLDDYCAWVLILNISNSLLEEFDQIA Sacce1 MITPRFSITQDEEFIFLKIFISNIRAVGLEIII-QENMIIFHLSPYYLRLRFSTAQYDSKDEINVKVAKLNKNEYFEDLDLPTKLLARQLIQEVEIEQKMNLYDTVINDINELDANDRRLRKENLKFDPEYYVSEYMNGIKELLKFTEFT--DEEQKQMQDLPKKSYLVLYVTILSVLFSYVFEQIENEGTTTESAWTMGKLCPQISFLDSLIKIAIITRRALSYPLHRNYDLAMKAFVYYILRGGKRVIRALLDIHETFRYVYDKVLLDDLTAWFIIRSLALEMIREMEILA Salro MLTPQFSLRQDDQFVYVTIRAPYVKISEVDMAI-SGNMFQLHVAPYFLRLCFETSKYDIDKRFYVTLPKKEPGP-FPDLDMQTLLMSRRLIQVLEVEQTFGKYSGTLPDITQLSPANRRIAHEDEHFSVDHYLGDFADMLSHVLSHREFT--EEEQEAMRQLRRVEVLAALLTALDIMCAFLYENRTTEGDSVESGWTIRTLSSALSFLDTSAREVLHAARSLSYPLYRSYALTTRVDLHDVLLIGKPILQCLLGARRLLAYVLNDIYLNDLCVWIQIDSFAAHVLEAIEALL Schco3 MITPRFSCDQTDEHVIVKVYCPAIRASDVDIHV-DDTLLTIHINPYFLRLNFSAARYDAGAGLYVTLNKQVKGQEFKDLDLLSKLLAPRAIEVIQYPQTVNMYSGYLNEVNELTPQMRRIAHENEKWDEEHYMADYAEYIQELLQWREFT--EDEKMMMLRLPRKE--SLYATLITILFAYAYEARTTQIETPESAWTLCSLTPAFSALDENLATALVPRRTLSFPLYRSFALAEACDVASLLARGKRVLRSLLATKRILDYLYSKLWLDDFCVWVQLMDLGTRLLEALEEAA Schpo1 MITPKFELRQDEEFVYLDVHTPYIKAKNVEIDA-FNNEVNFCIAPYFLKLELANASYDISSGVHIKFPKETPGEVFPDLDLLTTLLVNQLIEEVGLLQRLNQYSGLLNEINQIPPSTRRVQLEDEKFDAEHYMADFYEMIDEILHYIEFT--SEEKEALAKLPKRSYLIVYLCLVPLIFAYAYDNRTTLGDTIESCWNIGTLSSTISCLDLAIKDIFIARRSLAYPLYRNWDLALTCDTHAILSLGKRILRVLLRIRNLFEYIYNAIVLNDYAYWI-LAALAYQVVQETIIAS Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 MLTPAFTISQDEEFVTVVIKCPYIKAQEVEFFI-NDTEFKFYVRPYFLRLTFEKASYNVDRGITVLLPKATRGEEFPDLDLITKLMASKLIEVIDYPQEVNAYSGYGQEILDITPSTRRIAREDAKFDDEYFMADFVEEIQRLIKFRTFT--EEEQERMRQLPNKEYLLIYLGLVDIVYAYCYNYRTTEGETVESPWTIAKLSSTLSCFDSTLRETLIARRTLAYPLHRHFALSLRCDTAILFKLGKRLLKVLLEVNALIGYVLSTLWLTDYCVWIQLQSLASELLEELEQVA Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 MITPRFSCAQTDDAVVISIYCPSVRASEVEIHV-DENIFSVHIAPYFLRLNLSGAKYDPGSGLTVTLTKENKGQDFPDLDMLARLLAPRSIEVLQLPQTVDMYTGYFNEVNELTVSERRIAHEDEKWDEEHYMADFAEYIAELISWEPFT--EAENMTMLQLPQKEYLALYLTLVTLLFSYAYDARTTQHDTPESAWTISVLTPYFSALDSVLSNALIPRRSLAFPLHRSWLLAERCDVAGFLQRGTHVLRSLLEIRAILDYVYSRIWVDDLCTWVALSELGKALLEALEEAV Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------MEVAG-------------------------------------------------SELLAAA-----SFPARRNAHAEFFPLILDSTVEQRMREREAGDFDSEHYMAEYAEAIDELLGEHELD--TDERDELMALPAKEHLVELNGLLEILAAYAYDMRMTGGENVESAWTVAKLNGLTSWLTHSPREALLSRRSLVYPLYRSWKLASRIDALMIACTGRMVLKALLDIHKLFKYYFNELYIEDYCVWIQLAWLASSLIPFWEAAA Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 MITPAFTVEQDHSSVTIKINTPHVRAQDVDLFV-EGSEFKFYLKPYFLRLQLSTANYDIATGFTIMVTKETAGEHFEDLDLLTKLLARRLIEVIQLPQELSQYNHYFNEINCVTAESRRVNEENAKFDEDYYVNDFVEEIDDIIKYKEFT--EKENSIMRTMPNREYLLIYLGLIDILFAYSYNHRQTEGETVESVWTIGKLSPSIAGLESTLQETLISRRALAFPLYRNYKLCDKIDVYILLKLGKRILKALLEIKDMFDYIYSKIWLDDYCIWIQLKTLARELLEDLEEIA Ustma22 FSVPEYQATQDEGHVFIDVRCVARMRQKPNIAV-EGRIFGLHFDAYYLPLVLQAAKCESSSSWRVTLNKVQPGEHFDGLEQVQPQLLPEAVEGASMEDRMGSFGGALRNVLEVDPVERAIAFEEERWDEGIYMDNFLDELAPVLRFQ--------------PPRTTSSATIALVLQLVFAYSYDERTNQADTVESGWTIAKLSR---CLSTSLESVILSRRALTMPLYRHWQLAIACTLHHL-DAGQSLIDCLVAIESRLKCRLAEIWLAPLIAHVPIRSVMRTGLQVLEEAA Walse1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 MITPKFRITQDDDFVHIKVNVSSLRAAGLEMVV-EENVFVFHLSPYYLRLRFSTARYESKDEIDIKLPKEVKGQFFEDLDVPTKLLARQLIQEVEIEQK-NFYDTIINDINELGSNDRRLEKEKLKFDAEYYVSEYMNGIKEVLQNTEFS--DKEQTQMQNIPRKEYLIPYVTVLNILFGYIFEQIENDGINTESAWTIGRLVPQISFLDSIIKAAVITRRSLCYPLHRNFELILRAFVYYLLRGGHRIARCILDVHEVFRYVYNKILLDDLCSWFLIRSLAVELLKEMELIA [Cluster3488.fasta_al_trimmed; alignment length = 144] Allma1 LETVEWVADTE-PAHTNAILSTF-PDFAHLKRIRLSILLGHGVSRWPPLTRAQYVAHVVKVE-TCSAGLAHDTRTTFHPLAHTAMNLIDQVAQA-ATYLCTGLMVVLTHEPCIMCSMALLHSRVDSVVYVHTERRLNHKFKAWR Ashgo11 IRDSKWTVEIV-PRDSPHLMKFLKESYLHCKRLRLCVIIC--LPRAGPSTRELSISDTASEK-RVSAFVAVDQR-GGNPLHHSIMNGIKEVARDEDTYLCLDFDVYTTHEPCSMCAMALIHSRIKRCIFMHSSKALNSKYEVFQ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 ----------------------------------ISLLLCLAVPARPALTLAHLLVALAGKA-KAAALLTHDTRSDRHPLRHPVMNLVRLVG-TRADYFLTGRSLFLTHEPCVMCAMALVHSRVREIYVVVGLPNINHRYRIWR Batde5 FEPVQYVTTID-ARSVGKLLRPLATSLHHLKRVRIQVILAQMVSKWPAYTRAQFSIHMAHAF-RAAAVMGIDGRD-RHPLAHATMVCIEAVAVAEEGYLCSGLDMYLTREPCAMCAMALVHSRIGRVFYLHVHPSINHHYQVFR Botbo1 VKLMDWAVDMRDSKQTSQMIAFIKKSLKHLKRARVTVLLAVSVPRFGSSTPEQIVVGEARRA-KVACYVSTDTRSTAHPLRHAVINTIKTIA---EAYLLTNLTLFTTHEPCIMCTMALLHSRLKQIFFVVGLRGVNHRFTVWK Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------ Caeel IPSTSQALRLENKKIIGTIIRRLPEELSHLKRVGGSVLIAVKVARTKPQTRRQF---------R-----QNDELPSSHPLGHPVMEMVGNLPKR-DDYLGTGSDVFLITEPCAMCSMALVHFRVKRVFYLHLEPSINHHYEVFR Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------ Cangl IQPLDWTIDIQ-PQLSKSFIELVKLPLAHCKRIRLRCIIC-KVPKRGPYDKDLVIQEESKRI-GVSVFVAVDQRHLSLKIDHSIMVGINKVANTEQNYLCLDFDVYTTHEPCSMCSMALIHSRIKRCIFMHANKKLNSKYEVYK Capow MPTARIVARVDLPKQMSAVIAFIQQRLEHLRRVRMQVLICTDVPERIAANQQQHAIAQAQAA-RIGAVVVGDCSE--HTLAHAAMVAIARVADAQLPYLCTSYDLYITREPCVMCSMALVHSRVGRVFFIHAEPKLNHHFLAFR Catan2 FEPSLWVGDID-PKVATNVLKSF-DDLMHLKRIRLCVILAVGVSKWPPLTLAQY---LCNEA-GCSAAVAVDTRSTGHPLAHAAMNLIAAVAAANALYMCTGLTVVLTHEPCIMCSMALLHSRVGGVVYVHTERGLNHKFLAWR Cioin VGALKVACVLVDKKHASAVLKFLHEGLQHVKRMRLVFVSAVQVPSAIPLTREQFAIQTAKSANNVGVVVTFDLRNVAHPLNHAVMVAIDLVAHTQSSYICTDLTLYVTREPCVMCCMALLHSRIKRVFYLNAMKELNHRFVVFK CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------ Conco1 VESVEYALDLK-PQDSNKILKQYVSDYLFLKRFKLTILLSN-VPKYQPLTRDQF----------LNSVIECLHSP-KTPVDHAIMKSIEVVAQKEKGYLCKDLDVITLQEPCAMCSMALVHSRIRKLFYMHQLNDLNHKFRSYR Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------ Copci IRTVNWVVDVPEARHINTLIKWLKQDVSHLKRIRSTLLLSVPVPVSAALTIPSLAVRAATEGKRMAAHIACDTRSTSHALRHSAINAIRKLADYQSNYLLTNQTIFLTHEPCIMCSMALLHSRVREVFYLPTLKGVNHRFTIAR Croqu1 LELISWVIDCADNRWISKLFGFLKN-IDHLKTLRTTILLSIKAPRRASRLQSQSVLSLAIGS-YVATTVGVDLRSTQNPLCHAFIQMINNVARLD-PYLLTNLVVFATHEPCLCCSMALLHSRIKHLFYVHEQEGLNHKFYSWK CryneH991 RELMQWILEFSDAKLTKTALNFSKERLRHLKRVCCRIALCWSVPSSGARTQEQLVLKLAVDA-KVATFCSCDTRSESHPLRHATLNCVASIAHLRADYLLTSLSLFISHEPCVMCAMALLHSRVREVFYIHARRDLNHRFEVWK Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------ Dmel IALIK------ELETKQQLQAVIQEKLPHFQHLKRSVLICVEVPERMPRLRVQYLVRLSRDVNACCMMLKKDTTMNNEDYKDLTFGAEKSRECKEGPYLCTGYDIYLLQEPCLMCSMALVHSRAKRVFFLHSVRELNHHYEVFQ Enthi RELIKIVGRIIEKKMTGKIMKEIQEGMNHLKRIRLEIIICIEVPKYAPVNKEQY-----LNINQCIALVQKDTT-SNHPLLHAPFNALQSIPLNH--YLCTGFDLFTTHEPCLMCGMALLHSRFGRVFFLNKKKQLNHHFNVYQ Falba ------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 IRTIKWIVDVPDPKQTSLLLKWVKIDLAHLKRIRSSLLLSVDVPELVALTPKSLLKDEARMA-EIISYVARDTRSTLNPLRHSVLNVIRKVADWRSNYLLTGLTLFTTHEPCMMCSMALLHSRVREVVFVPRLKGVNHRYNILR Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 IKTVDWVVDVPEARHITTLLKWLKQELGHLKRVRMSLLLSIPVPVSSALTLPSLAADMAIKAQSVAAHIASDSRSTQHPLRHAAINAIRKMADYRANYLLTDRTFFITHEPCIMCSMALLHSRVKEVFFLPTLKGVNHRFAILQ Ganpr1 -------------------MSFLSV------RSQLLLLLCVAVPSSRTVPLF-FIVGLARAG-T----VARDGD-ARNPLRHAVMELCGVVAGQEDAFLLTGLSIYTLHEPCLMCAMALVHSRVENVFY--ADTSTTTTTAAAA Gloin1 ---------------------FIKKILDHVKRIKLTVLICQQVCKYPAITRTQFAIKLSIQA-KIGCIMSFDTRSTKHPLSHAILNCINNVASLETTYLCKGFDIFITHEPCIMCSMALVHSRIGRVFYIHTHNSLNHHFKVFK Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 IRDTKWSIEVR-PRESKSVIPFVR-SFLHVKRIKLRVLIG-KVPKVGPSTKSLMIAEESRAI-RVSAFVSKDYRHSGSPLDHSVMVGINEVAKEEETYLCLDFDVYTSHEPCSMCSMALIHSRVKRCIFMHSNKDLNSKYEVFQ Lacbi2 IRTMQWVTDILDQRHIATLLKWLKQDLSHLKRIRTTLLLTLDIPASSALTLPSLAIEAAIEA-HIAAHISCDTRSTQHPLRHAAINVVRQMADHRTNYLLTNLTLFMTHEPCVMCSMALLHSRVKDVVFLPTLKGVNHRFNIMQ Lenti61 VRREDWIVDLPDPRLAAVMLKWLKQSMAHLKRIRSMVLILAPVPTSAALTMTSLVVKKAQYI-GIAAYVAHDTRSASHPLRHSIINLVRAVGELRAHYLLTSLTLFTTHEPCIMCSMALLHSRVKEVFYVPRLEGVNHRYAVNV Malgl1 LHTTRWAMDIP-PRACSPAAQILKRSIRYLRSFRLSLLLCVRVPTGPAPSPERLCIATAQQA-RIGVFVAHDTRRDAHPLRHAVLNAVRRVAHIRQDYLLTGLTMFITHEPCVYCAMALIHSRVRSVFFIHEQSGLNHKYEVWR Mellp23 --------------MISKLFEFIK-SINHLKSIKSTILICIKVPYQLSKDMTKSVLNSAYESFKVGVLVAIDKRSSCNPLSHSFLNLITNVSIQDRPYLLTNLVVFGTHEPCLCCSMALLHSRIHHLFYFNNLNGLNHKFFVWK Mnele -SELPVAVGILNKKILSSLIKIVSSS---YKRV---LLVCVNVPSRLPFTQRQNSMKTESSVNF--VMV-----CNASLLGHAAMRVIDQIAKAQ-DYLCTGYDIYFAIEPCIMCTMALVHSRINRIFFLQEISALNHSFEVYH Monbr -----WETIVG--------------TLGAVSKVS--------VPARAPETRAQY---------------GLTPRCHGAPKRKPSFTACR-------------------------CAMALVHSRVQRAVFMHAHPGLNHRFDVYE Morel2 LETVNYIATIE-PKQTNQVIKFVRGGLDHIKQIRLDIVLCHGVPKYPPLTRDQFVWGHAAEA-TIVAMISYDTRSTGYILQHAVMNCVAAVAKREKAYLCTGYDVFLTHEPCVMCSMALVHSRVGRVFYIHSHPNLNHHFFVYR Mucci2 LETIDYTAHVE-PKQTNSILKFAQKGLEHCKKIRLEVILCVPVSKHAPLNRQQFILANQ-QH-SVVCRVKSDTRE--HPLHHAVMNSIDHVAQNEAAYLCTGYDIYITHEPCAMCAMALVHSRVSRVFYIHAHASLNHHYRVFR Mydma -----------------------------LKDERENFIQC--VSDSPPLTRQQFVQDIFSTENRSAAVIAHD--TESDPLKHAVMVAIDMIAWQQGGYLCTGYDIYLTHEPCVM------------------------------ Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 --------------------------------IE------SKASKYPAFTKNQFALKKAEEN-KNNCTVETDNRESNHPLKHSVMECIKSISEIHLPYLCSNYDLYTVKEPCIM------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 LETVDYITNVE-PKETNNVIKFIQRGLEHCKRIR------IRLSKHAPKNRQQYLIDNS-CG-QMRARIESDTRETVHPLHHAVMNCIDTVGFKEAAYLCTGYDIYITHEPCAMCAMALVHSRIARVFYIHSHLSLNHHYRVYM Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 IRTLQWVVDIPDPRKITTMLKWLKQDLGHLKRIRSTLLICVPIPSTAALTITSAIASQAMSA-SIVAHVAHDTRSTAHPLRHAVLNVIRSIADHRSNYLLTSLSLFTTHEPCIMCSMALLHSRVKEVYFLPRLDGVNHRYGIWQ Polpo ------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 PDSLEWIIDCDHPRYISALFQFIR-SIKHLKSIKVSVLLSIRVPTKRALYE---VAQLALTSKLVGAAVSVDRRSSSNRLRHAVVELTTTVSAQD-PYLLTNQIVFLSHEPCLLCSMALLHSRIKHLFFVHEQDGLNHKFFAWK Punst1 IHTMDWIVDVPDPRLITLLLEWLNKTLGHLKRIRSFLIYPTKVPSYPARTQNSLLYDEAVRA-RVVAHVAHDLRSTKHPLKHAALNCIRKIADYRTNYLLTGLTMFITHEPCIMCSMALLHSRVKEVVFIPRLEGVNHRYNIYR Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 LMT--YAIDLP-ARCAGAVFQFVRKELSHLKRVRQSILLFVEVPAEAAHTEQQAVWERAEEA-GIACRIAHDTRSTGNVLTHAASNAIDAVAYLDPPYLLTGLTVFLSHEPCLLCSMSLLHSRIKNLFFVHEDGGLNHRFEVWE Rozal11 IEDFKVRDRLLNQQLP------LSK----LKRIR--FVTCVQVPNRGAVSKVEFSIVLEDLLNKDGFIVEAKIDSASSPLGHITMKLINTISSK--SYLCNGYDIFLKYEPCLMCSMALVHSRIRRVFFL-SQTPVNHKFYAFE Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------ Salro MTVVPVVACIPDKKKTSTILRSLQRDLKHCRRVRLEVIVCASVPAFCPLTRTQMLRELAGKA-AQRCAIANDQRA--HPLHHEVMMLIDQVARARSSYLLKGLDVFLTHEPCIMCSMALVHSRVGRIFFIHQHDNLNHRFDAFA Schco3 VRTIRWAVDIPEPRGTGKALKWLKDTLGHLKRIRSTLLFTVTVPAFAAQTLTSLAVEGGLKA-KVYAWIARDTRGTGHPLRHAAIDVIRQVAEYRQDYLLTGLTLYLTHEPCIMCSMALLHSRVKEVIYLPWLQGVNHRFRIGR Schpo1 LETENWIACFE-PKYASKVTQYVKQSLLHCNRLRLQIIICYAVPAFPPLTDEQFLINAAGAS-HCAAAISVDERKLKNPINHCVMNAINLVAKREDRYLCKDLTVVMTHEPCVMCSMGLLHSRIRRLIYIHWRAELNHRYLAYS Sorma ------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 LQTVEYRTAVD-PKHASKLIKAVCQDLAHLKRVKLSVLLASQVSRYAAVTREQFALEESKVL-R-VAIISTDTRD--HPLHHAVMNCIALVAERESGYLCSGLDLYLINEPCAMCSMALVHSRIARVFYIHVHPSLNHHFKVYR Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 IRTMQWVVDIPDPRHLAVMLRWLKEELSHLKRIRSTLLISITVPRTPALTPNSLVVSEALKA-KIVAHVAHDTRSAQHPLRHSVLNVVRQVADFR------------------------------------------------- Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ----------------------MSA-----KRQRLAAVLRALVREHLTMPI----VGAAIAA-ALVVAV--DG--------HLVMDALASVAAPEDAFVVG--------EPCSMCAMALLHARIARVVVVHAQRALNHSYAVYR Treme1 IEDLSHILVFKGESHADISISFSKD-LRHLKRVHCLVAVCLSVPSTGAKSPQQLVLHLATEA-KVAVYCAIDTRSEKHPLRHSAFNCIAQIARLRADYLLTSLTLFMTHEPCVMCSMALLHSRVREVYYIGGRKDLNHRFEIWK Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 LGTQSYITDID-PKKTTILLKFIQRGLEHCKRIRLSVLLCISVPLYAPLNRTQFLITKS-QN-SVFARVGSDTRADKHPLHHAVMNCIDNVALSEVAYLCTGFDIYTTHEPCTMCSMALLHSRIGRVFYIHSHKSLNHHFKVFG Ustma22 LATRDWIIDIA-PTSASLAVKFLQKSTRHLRSFR---LLCAPVPVIAAPTKQRLVVALARHA-LSAVHVALDQRLRRNPLKHGVIEAIARVSVLRSDYLLTSLSLFSLYEPCVYCTMALVHSRVSEVYFLQEQKGLNHSFAVWQ Walse1 PYLFDWIVNLTNPIQTRELIRFAIHRTKHLRRIRISVFLALKVPARRATTAEEYAKYLALEA-QIAAHVGYDTRTTGNPLNHAIFNCVRQVGELRAEYLCTSLTLFSTHEPCMMCAMALVHSRVRDIYFVHEMPNLNHHFEAWC Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3489.fasta_al_trimmed; alignment length = 107] Allma1 IMPKMGNQTLRAALGRSSWHLIHTMGNTYPNAPQPDEQESMRLFIYLIGRLYPCGDCAEHFQAMLRTHPPEPHLGSRDALSQYLCKLHNKANLRLGHTVFDCDRWKC Ashgo11 IMPGMPDPTAKQELGRATWKLFHTMLARFPDEPSEQEREKLHTFLHLLAELYPCGECSVHFVSWLKKLPPQ--TSSRSAAATWGCSIHNKVNLYLGKPAYDCEDYDC Aspfu1 IMPGLGNETAKAELGRATWKYFHTMLARYPEDPTEEQQETLRSFILLFARLYPCGECASHFQGHLKKYPPQ--VSSRNAAAGWGCFIHNEVNTMLGKPEFDCDFYDC Aurde31 IMPKLGNATARAELGRATWKLMHTMTLRFPEEPTAEEREALNQYFYLMSKLYPCGDCAAHFQKMLAKFPPQ--TSSRKAASNWLCYVHNQVNERLGKPQFDCDTYDC Batde5 ----------------------------------------------------------------------------------------------------------- Botbo1 IMPVLGNATAKALLGQSTWRLLHTMTLRYPEHPTPDERAALKSYFYLQARLYPCGECAEEFQQLLEKYPPQ--TSSRKTASLWLCHIHNLVNERLKKPQYDCETYDC Botci1 TAPKLENATLKAELGHAAWKVLHTMMAKFPDKPTEEDSSALKSYIHLFARLYPCGDCARHFQGLLKKYPPQ--VATRSTAAAWACHVHNEVNKRLKKEIFDCDFYDC Caeel ----------------------------------------------------------------------------------------------------------- Canalb1 FMPKMANETLKAQLGNASWKLFHTILARYPDEPSDQERNTLENYIHLFAQVYPCGDCARHFTKLLAKHPPQ--TKNRKTAALWGCYVHNIVNEKLNKPEYDCEDYDC Cangl IMPLMEDKQAKVELGRASWKYFHTLLARFPDKPTKEERQKLKTFLELYAELYPCGECAYHFVKLMDKYPPQ--TSSRTAAALWGCHVHNIVNEYLKKPEYDCEDYDC Capow ----------------------------------------------------------------------------------------------------------- Catan2 IMPKMGNETLRAALGHSSWHLIHTMGNTYPLKPTRDEQNAMLSFIQLLGRLYPCGDCAQHFQQMLAMHPPEPHLGTRDDLAQYLCKLHNKVNLRLGHKIFDCDRWKC Cioin ----------------------------------------------------------------------------------------------------------- CocheC53 IAPKLGNATAKAELGRAAWKVLHTTFARFPEKPTEEEKEALRSYVHLFQRLYPCGECAEHFGQVLAKYPPQ--VSSRTAAAMWGCYVHNIVNKRLKKPEFNCDAYDC Coere1 VMGKMANETLRAQLGQRTWYLLHVMASRYPEEPSKDEREAMQSFLFLMSRLYPCGDCAHHFQQHLKKHPPI--VSSRNDLEQYLCNMHNVVNRSLNKPMFNCETYDC Conco1 IMSELGDPEIKAELGRSAWKLIHTMTARFPIKPSKDEQKALEQWFHLFSRLYPCGQCARHFQGLLVEHPPK--VGSREEASTWACEMHNFVNDRLKKPQFDCEMYKC Conpu1 IMSKLGNETAKAELGRATWKLMHTMTLRYPENPTQDHRDALESYFYLTSRLYPCGECAAEFQQLLKKFPPQ--TSSRRAASLWLCSVHNEVNARLKKPAFDCATYDC Copci IMGKLGNETAKAALGRATWKLMHTMTLRYPENPTQDERDALRSYFYLTSRLYPCGECAAEFQALLKKFPPQ--TSSRRSASLWLCAVHNEVNKRLKKPQFDCDEYDC Croqu1 IMPKMGNATAKAELGRATWKFMHTMTQRFPEHPTADERAALKAFIYLFSRLYPCGECAHHFQLLLKEYPPQ--TSSRNAASLHLCSLHNLVNERLGKPEYNCENYDC CryneH991 IMPKLGNATAKAELGRAAWRVLHLMTLRYPDEPIEDDRLALKSFFHLFSRLYPCGECAQEFQKLLKDYPPQ--TSSRKSASLWLCHVHNQVNARLGKPEFDCETYDC Crypa2 IAPKLGNETAKRELGRATWKFLHTMMARYPEQPTEDDQLALKTFMTLFSRLYPCGECAEHFRQLLAKYPPQ--VSSRNAAAGWLCFAHNIVNERLKKPTFDCDFYDC Debha1 FMPKMANETLKAQLGNAAWKLFHTILARYPEEPSKQEQTTLDQYIHLFAQVYPCGDCARHFQGLLAKYPPQ--IKSRKTAALWGCHMHNKVNERLEKPEYDCEDYDC Dekbr2 ----------------------------------------------------------------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------- Fomme1 IMSKLGNETAKQALGRATWKLMHTMTLRFPEEPTEDERHALESYFHLQARLYPCGECAAEFQKLLEKFPPQ--TSSRRAAALWLCHVHNQVNERLEKPEFDCETYDC Fusgr1 IAPKLENATLKAELGHATWKFLHTMMSRFPDKPTKDDRMALETFMHLFARLYPCGQCAEHFRKLLAQYPPQ--TSSRNAAAGWLCFAHNIVNERVHKPLFDCDFYDC Galma1 IMGKLGNATAKAALGRATWKLLHTMTLRYPEHPTADEREALSSYFHLSSRLYPCGECAAEFQLLLKKFPPQ--TSSRRAASLWLCALHNQVNERLKKPEFDCDEYDC Ganpr1 ----------------------------------------------------------------------------------------------------------- Gloin1 ----------------------------------------------------------------------------------------------------------- Hisca1 VTSKMGNETAKAELGRSAWRVLHTMMAQFPDKPSAEQQETLRSFIYLFSRLYPCGECASHFQAHLAKFPPQ--VSSRSAAAAWACHVHNEVNKMLYKDIFDCDFYDC Klula1 IMPKMPDQEAKKALGRASWKYFHTLLARFPDEPTEQEKTKLREFLYLYAELYPCGECSYHFVKMLKKYPPQ--VASRTTAALWGCHIHNLVNDHLEKPRYDCEDYDC Lacbi2 -------------LGRATWKLMHTMTLRFPEHPTLDEREALSSYFYLTSRLYPCGECASEFQELLKKYPPQ--TSSRLAASSWLCAVHNEVNARLNKPEFDCDEYDC Lenti61 IMPKLGNATAKAELGRATWKLLHTMTLRFPEEPSQDERDALNNYFHLMSRLYPCGECAAEFQLLLKKFPPQ--TSSRRAAATWLCFLHNQVNARLGHEEFDCATYDC Malgl1 YAPAMTNATAKAELGRSTWRFLHTMMARFPENPTPQQSEDLRKFIHLFSLLYPCGDCAAHFQQLLKEWPPQ--VGSRHNAELWLCNAHNAVNTRLHKPQFDCETYDC Mellp23 IMPKMGNATAKAELGRATWKFMHTMTQRFPEHPTPDERAALKSFIYLFSRLYPCGECAHHFQLLLKQYPPQ--TSSRNAASLHLCSLHNLVNERLGKPEYNCENYDC Mnele ----------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------- Morel2 IMPQLGNATAKAELGRATWKLLHTMASRYPLKPKPDERAAIKQWIYLLSRLYPCGECADHFQEMLKQHPPQ--TSSRASLSNWACSVHNIVNIRLGKPEFDCDVYKC Mucci2 ----------------------------------------------------------------------------------------------------------- Mydma ----------------------------------------------------------------------------------------------------------- Neucr2 IAPKLENATAKAELGRASWRLFHTMMARFPETPTAEESLALKTYIQLFARLYPCGDCASHFQKLLKKYPPQ--TSGRNAAAGWACFVHNEVNKRLKKEQFDCDFYDC Orpsp11 IMPDMFNITEKEELGRSTWRLLHTVTARYPNKPTNEQK--------------------------------------------------------------------- Pench1 VMPKLGNETVKAELGRATWKYFHTVMARFPEKPTEDQKEALRSYIYLFARLYPCGECAEHFMQHLSKYPPQ--VSSRNAASGWACFVHNEVNAMLGKPEFDCEFYDC Phybl2 IMSHLGNATIKAELGRSTWKLLHTMVARFPESPTSDERAALKQFILLLSRLYPCGECAEHFQKLLAKYPPQ--TSSRVAASQWACAIHNHVNQRLGKEIFNCAKYQC Picst3 FMPKMADETLKAQLGNAAWKLFHTILARYPDKPSKQEQATLKQYINLFAQVYPCGDCARHFRKLLNKYPPQ--TLSRKNAALWGCDIHNKVNTRLNKPIYDCEDYDC Plicr1 IMSKLGNATAKAALGRATWKLLHTMTLRYPEKPTQDERNALNDYFHLTARLYPCGECAAEFQQLLKRMPPQ--TSSRRSAALWLCHLHNQVNERLHKPEFDCDTYDC Polpo ----------------------------------------------------------------------------------------------------------- Pucgr2 IMPKMANATAKAELGRATWKFMHTMTARFPEKPTADEREALKAFIYLFSRLYPCGDCARHFQELLKQYPPQ--TSSRNVASLHLCSLHNLVNERLGKPEYNCENYDC Punst1 IMSKLGNATAKAALGQATWKLLHTMTLRFPEEPTPDEREALESYFYLLSRLYPCGECAAEFQQLLKKFPPQ--TSSRRSAALWLCHVHNQVNERLGKPEFDCETYDC Rhior3 ----------------------------------------------------------------------------------------------------------- Rhoto1 IMPKLGNATAKAELGRASWKLLHTMAARFPEKPTENERDTFKSFLYLFSRLYPCGECAAEFQQLLKKHPPQ--TSSRGSASLYLCHLHNLVNLRLGKPEFDCDVYDC Rozal11 ----------------------------------------------------------------------------------------------------------- Sacce1 IMPLMGDDKVKKEVGRASWKYFHTLLARFPDEPTPEEREKLHTFIGLYAELYPCGECSYHFVKLIEKYPVQ--TSSRTAAAMWGCHIHNKVNEYLKKDIYDCEDYDC Salro ----------------------------------------------------------------------------------------------------------- Schco3 IMPKLGNATAKAELGRATWKLLHTITLRFPENPTPDEQEALRSYFHIFSRLYPCGECATEFQQLLKKFPPQ--TSSRRSASLWLCDVHNTVNKRLRKPEFDCETYDC Schpo1 ----------------------------------------------------------------------------------------------------------- Sorma IAPKLENATAKAELGRASWRLFHTMMARFPETPTADESLALKTYIQLFARLYPCGDCASHFQKLLKKYPPQ--TSGRNAAAGWACFVHNEVNKRLKKEQFDCDFYDC Sphar ----------------------------------------------------------------------------------------------------------- Spipu1 IMSKMVNETLKAELGRSAWRLLHTMAGKFPVEPTVDEQEAMRDFVYLFARLYPCGDCARHFKVVLEANPPD--VTTRETISNWACKVHNVVNERLKKPIFDCETWKC Sporo1 VMPKLGNATAKAELGRASWKLLHTMAARFPENPTTSEREALKSFIYLFSRLYPCGECAAEFQALLKKHPPQ--TSSRSAASFHLCHLHNLVNLRLGKPEFDCGIYDC Stehi1 IMGKLGNATAKAALGRATWKLLHTMTLRYPENPTEDERAALSSYIHLTSRLYPCGECAAEFQKLLQQFPPQ--TSSRRSASLWLCHVHNQVNERLGHPIFDCDEYDC Tapde11 VMGKLLNETLKADLGRHAWFLFHTVLSRYPDTPTPGEREDLVQYVRYFTKLYPCGDCASHFQTVLERMPVQ--SSSRVAAAQWGCAVHNVVNARLGKQAYDCEDYDC Thetr ----------------------------------------------------------------------------------------------------------- Treme1 IMPKLGNETAKAELGRAAWRVLHLMTLRYPDNPTPDDRSALKSYFHLFSRLYPCGECAQEFQLLLKEYPPQ--TSSRKSASLWLCHIHNLVNARLGKPEFDCATYDC Trire2 IAPKLENATLKAELGRATWKFMHTMVARFPEKPSPEERKTLETFIYLFGRLYPCGDCARHFRGLLAKYPPQ--TSSRNAAAGWLCFVHNQVNERLKKPIFDCDFYDC Umbra1 IMGKLGNETIKAELGRSTWKLLHTMTARFPLEPTSEERTALKQWITLLSRLYPCGECAEHFQVLLKQYPPQ--TSSRDAASQWACAVHNKVNERLEKPMFDCDMYQC Ustma22 IMPKMGNTTAKEALGRSTWHFLHTMTLRFPEKPTKQESETLRSFFYTFAQLYPCGECARHFQQLIRELPPQ--VGSRKGASNWLCVVHNEVNKSLGKPEFACESYDC Walse1 ----------------------------------------------------------------------------------------------------------- Zygro1 IMPSMPDQEAKKELGRASWKYFHTLLARFPDEPTEEQRNKLNSFIHLYAELYPCGECSYHFVKMLETNPPQ--TSSRVTAAMWGCHIHNIVNEYLHKPIYDCEDYDC [Cluster3498.fasta_al_trimmed; alignment length = 81] Allma1 --------------------------------------------------------------------------------- Ashgo11 -SSCAARRDAIQDLYLKELRNAKVAAPGGAVRPWAEPARPSVPEFG-IAGNAAELEAYSQQPVE-GDWL--GAEESAAGH- Aspfu1 T-SAVRQADPVQELYLRQLQAYKPTPIKAHVQKFSAPAAPQSPE---EANLANDLKAYESQDVEEESWFPEE----ETAHH Aurde31 STSAVARKDLVQDLYLRELKAYKPAPAAGAVKDFAAPAAPQAPELP--GNFAAELSAYDAADPDAPAFLEADIPKHD-HHH Batde5 --------------------------------------------------------------------------------- Botbo1 SVNTVARKDLVQAIYVQELKGYKA-PIAGNVKEFSAPSSPTPPSLP--TDLASELAAYEQSEPTADAFLEADIPKAE-AHH Botci1 VPTAVRRADLVQDLYLKELKGYKVPQVKGQVLKFSPPKAPASPE---ETDIAKELAAYEASTVEEVDWFPEE----EAAHH Caeel --------------------------------------------------------------------------------- Canalb1 -SVTPRRSNLIGDLYIQHIKAFKPKALTSAVKAFQLPAKPSVPQAD-VN--AEAVKEYEASDVE-EDWF----EEVEEAAH Cangl -SSCRVSRNIISDLYLKELKSVKVTPFSGNVKPWSPPAKPQAPQSE-LTSGNDLLKSYKEEPVE-EHWL----SEEEPAH- Capow --------------------------------------------------------------------------------- Catan2 --------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------- CocheC53 TPTAVRSADLVQDMYLRELKNYKVPQVKGQVKKFAIPKAPASPE---ETDIASELKAYETQTVEQEDWFDESI-TTAGATH Coere1 --------------------------------------------------------------------------------- Conco1 FASSTAKPDAILGLYLKEIKNYKPAAVKGQVKEFKLPVAPEAPKFD--GDVQAEVSAYESQ-------------------- Conpu1 SSSAVSRKDFIQDLYVKELKSYKAPPPAGAVKQYTIPPAPKAPSLP--SDVAAELNAYDASEPSAETFLEKDEPKAE-AHH Copci GTTA-ARKDLVQDIYLREIKAYKPAAVAGAVKSFSLPPAPKAPALP--ADLAAELSAYDAAEPVPEAFLEQDVPKPA-HH- Croqu1 TTSFQTKKDFVQELYLRELKSYKPSP-STQVREFTMPPTPPAPYLPTAQDVAQELESWDKASLVADEYLERDHPTPTTAHH CryneH991 SVSAV-KMDLVQDLYVNQLKSYKPAAKAGSVRSFTAPKAPSAPALP--TDLASELSKFDAEEPTVEEYLEKDLPKAD-AHH Crypa2 NPTVSRRADFVQELYLKELKAYKPTPVKGQVLDFSQPKAPKSPE---ETDLASSLKEYESMAVEVEDWLDED----EEHAH Debha1 -SISPQRSNLVSDLYIQQIKAFKPTPLSSSIKSFQLPNKPSVPESE-IS--ADALSQYESSDVE-EDWF----EEE-EVHH Dekbr2 -HVSSFRPNLVQDLYIKELKAFKPKPLTEATMPWKLPQAAKAPALE-AEG-ADALAEYESSNVEPDDWF----EEDKA--- Dicdi --------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------- Fomme1 ASSSVARKDIVQELYLSELRSYKPPPAAGVVKPFTPVTPPKAPSPP--TDLASELAAYDAQEPSAKEFLEADLPKPE-AHH Fusgr1 APTVSRKADFVQELYLKELKAYKVPVVKGNVQTFSVPKTPASPE---ETDLAGNLKEYESMAVEVADWLEED----EEPHH Galma1 ASSAVSRKDLVQDLYVREIKSYKAPPAAGIVKKLAIPAAPTAPALP--ADLASELNAYDAAEPAADAFLEQDLPKPV-AHH Ganpr1 --------------------------------------------------------------------------------- Gloin1 ASGPV--KDIIQDLYVKEIKAYQPPSAAGQVKKLSL-STSEPPKID--ADVSSELTAYETEEI------EKQIFTEKENVH Hisca1 A-TPIRQAELVQDMYLREVRAYKFPPSQAHVQKFSAPKPPPSPE---EANLAADLKAYETQEVEEEDWFDEA----PAAH- Klula1 -STSFIRRNVIQDLYLKELKAVNLKPITGAVKPWTTPAAPKLPELE-LQS-ADALKEYASSGVE-GDWL----EELEDAHH Lacbi2 ASSAVSRKDLIQDLYVREIKAYKPAPIPGVVKQYSLPPTPKAPAPP--ADLASELSAYDATEPTADAYLERDLPKVE-HHH Lenti61 STSAVARKDLIQDLYIQQLKSYKAPAPAGVVKAYALPPAPQAPTLP---DLASELSAWDATEPTAEQFLEADEPKAE-AHH Malgl1 SSSAVARKDILQEAYLRELKAYKAPEKSGHVREFSSPPSPQAPSMPSSSEIASQLESFTSSEPDVNEYLQADI-KVE-AHH Mellp23 TSSSLSMKDFVQELYLRELKSYKPSP-STQVREFTMPPAPSAPVLPTSQDVAQELQSWDSASLVADEFLERDHPAP-AAHH Mnele --------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------- Morel2 APSAPLMQDILKDLYIKELKGYKPAPEASQVKEFKAPAAPAAPAV----DAAADLSAWETANVETEDAVEEEVEEVEEHHH Mucci2 SAAAVMQKDVVQDLFIKELKGYKPAPAASAVKELKLPAAPAVPEVD--ADLSQQLAAYD--------------AEPEEAAQ Mydma --------------------------------------------------------------------------------- Neucr2 APTVSRRADFVQELYLKELKAYKPTPIKGQVATFNLPKPPKSPE---EADLASSLKEYENMAVEVEDWLEEE----EGAHH Orpsp11 --------------------------------------------------------------------------------- Pench1 T-SAVRQADPVQDLYLRELKAYKPTPIKEHVQKFTAPKPPQSPE---EANLASELSAYESQEVEEESWFEEA----PAAH- Phybl2 --------------------------------------------------------------------------------- Picst3 -SVTPRRSSAIADLYIQQIKAFKPVALSGAVQAFQLPAKPAVPSSE-IS--AEALNAYETSEVE-EDWF----EEETEEHH Plicr1 SSSTAARKDFIQDLYLKEIKSYKPAPAAGVVKAYALPPAPQPPTLP--SDLAAELSAYDAAEPTADAFLEAD-VKAE-VHH Polpo --------------------------------------------------------------------------------- Pucgr2 VSSSSIKKDFVQELYLRELKSYKPAPQSTQVRDFTMPAAPAAPAVPTAQDIAQEMQSWDSASLVADEFLERDHPPP-AAH- Punst1 ASSAVARKDFVQDLYIKELKAYKAPPVAGVVKSFAQPPAPQAPAIP--SDLASELSAYDAAEPTAEAFLEADPVKHDHAHH Rhior3 SAAAVMKKDVLQDLFLKELKAYKPQPVASAAKDLKLPPAPAVPEIE--GDISQQLAAYD--------------AEPEEIAQ Rhoto1 SATSAPRKDLVQDLYLRELRSYKPKPAAGATKSYSTPSAPKAPEVPDAKALAGELAAYEASTPDADDFLEQDV-KVE-AKH Rozal11 --------------------------------------------------------------------------------- Sacce1 -TTTRISYNVIQDLYLRELKDTKLAPSTGNVKPWNPPQKPNLPELE-LQG-PEALKAYTEQNVE-EDWL--DAEETKESH- Salro --------------------------------------------------------------------------------- Schco3 ATSAAARADIVQQLYIKELKSYKPAPAAGQVRSWSAPQKPAAPALP--TDLAAELSAYDAAEPTAEEFLEADPVVEEHEHH Schpo1 TTSPRLYVDVVQGLYISSLKSYKPKAVPAEVKEWSMPSAPTAPKYD--VDFTSALNSYKYEGETESNKFES--YENEKEH- Sorma APTVSRRADFVQELYLKELKAYKPTPIKGHVATFSLPKTPKSPE---EADLASSLKEYENMAVEVEDWLEEE----EGAHH Sphar --------------------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------------------- Sporo1 --------------------------------------------------------------------------------- Stehi1 ASSAVTRRDLVQDLYIKELKGYKAPPAAGTVKSYSAPAAPQVPTLP--SDLASELSAFDASEPTAEAFLEADEVEEH--HH Tapde11 --------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------- Treme1 SVSAMGRKDLLQDLYVSQLKNYKPAPQAGLVRNYTAPSPPQAPALP--TDLASELAKFDSEEPIADAFLEKDQPKEE-VHH Trire2 APTVSRRADFVQELYLKELKAYKTPAVKGQVQVFTMPKTPASPE---EANLADSLKAYESMAVELPDWLEEE----EEPHH Umbra1 TPSMPVQKDVIQDLYLKELKNYKPAPVTGQVKDLKLPPTPAAPVVE---DLTEELANYDK---------EPVAEEAEEAAH Ustma22 SSSAVASKDFVQELYIKELKGYKAPPKAGQVREFQTPAAPKAPAVPSSSELSSQLEAYAAAEPDVNAYLAADV-KVE-AHH Walse1 SASAYASKDLVQELYLSQLKSYKAPPKAGHVKTFKQPETPAAPSVP--TDLATELSSYEAAQPTAEEFLEADLPKPE-AHH Zygro1 -STTLTRQNALQELYLKELKNVKLSPLTGSVKPWIEPSKPSIPELE-AQG-ADALQAYKDEPVE-EDWL--DAEEESSHH- [Cluster3501.fasta_al_trimmed; alignment length = 239] Allma1 FAPIRESDVSREMTKRYMTSLADTDVVIIGAGPAGLMCAYELSKD-PSIKVSVIEASVAPGGGAWLGGQLMTPMVVRKPAHLVLDELAIPYDDYVVVAHAALFTSTLIATIINGVKLFNATAVEDFIVKVVCGVATNWALVTKAHGTQNCMDPQTVLAVIVSSCGHDGPHGATGIKRLHQGMKALHMEAAEDAIVANTQEIPGMIITGMEVSEACGTNRMGACFSAMIVSGRKAGWLAR Ashgo11 FAPIREATVSRAMTTRYFEDLAVSDVVIVGAGSSGLSAAYVLAKNRPDLRIAIIEANVAPGGGAWLGGQLFSAMIMRKPTHLFLDELEIPYEDYVVVKHAALFTSTVLSKVLPNVKLFNATAVEDLVTKTIAGVVTNWTLVTMAHDVQSCMDPNVIELVVLSTTGHDGPFGAFCAKRLAAGMQSLDMNTAEAGVVKESGATEYMYFAGMETATKKGVSRMGPTFGAMAVSGIKAAEEIL Aspfu1 FAPIRESQVSRAMTRRYFQDLAESDIVIVGAGSCGLSTAYVLAKARPDLKIAIIEASVSPGGGAWLGGQLFSAMVLRRPAEVFLNEIGVPFEEFVVVKHASLFTSTLMSKVLPNVKLFNATAVEDLVTRQIAGVVVNWTLVTLHHDDHSCMDPNTINAVVISTTGHDGPFGAFCAKRLVSGMRGLDMNSAEDAIVKNTREVKGLIIGGMELSEIDGFNRMGPTFGAMVLSGVKAAEEAL Aurde31 FAPIHEAEVSRAMVKRYFTQMAISDVVIVGAGSAGLSCAYHLAKSRPDLKITIIEASVAPGGGAWLGGQLMTAMVVRKPADRFLTELGVPFEDFVVVKHAALFTSTILSRVLPNVVMMNATAVEDLIVRRVSGVVTNWTLVSLNHDTQSCMDPNVIVAVVVSATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNGTREVPGLVMCGMELSEHDGSNRMGPTFGAMMGSGIKAACEAM Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 FAPIRESQVSRAMTRRYFNDLAESDIVIVGAGSCGLSTAYMLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVMRKPADAFLTDLGVPFEDFVVVKHAALFTSTLLSKVLPNIKLFNATAVEDLITRRIAGVVTNWTLVTMHHDDQSCMDPNTINAIVISTTGHDGPFGAFCVKRLVSGMRGLDMNVAEDAIVKRTREIPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEAL Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 FAPIRESTVSRAMTRRYFADLAESDIVIIGAGSAGLSAAYTLGKNRPDLKIAIIEASVSPGGGCWLGGQLFSAMVLRKPAHLFLDDMGLDYEDYVVVKHAALFMSTLMSKVLPNIKLFNATAVEDLITRRIAGVVVNW--AQLDHDTQSCMDPNTINCVVLSTSGHDGPFGAFTAKRLEQGMKGLDMNKAEDAIVKGTREVPGLVIAGMELAEVDGSNRMGPTFGAMALSGVKAAESVL Cangl FRPIRESTVSRAMTSRYFKDLAVSDVVIIGCGSSGLSAAYVIAKNRPDLKIAILEANVAPGGGAWLGGQLFSAMIMRKPADLFLKELEIPYEDYVVVKHAALFTSTVLSKVLPNVKLFNATAVEDLVTRSVAGVVTNWTLVTMAHDLQSCMDPNVIELVVLSTTGHDGPFGAFSAKRIVSGMKGLDMNNAEAGVVKNSGSYGSMYFAGMEVAELEGCNRMGPTFGAMAVSGIKAGEEIL Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 FAPIQESQVAREMITRYMHQMADTDVIVVGAGPAGLMAAYEASKD-PSVRVAVIEASVAPGGGAWLGGQLMTAGVIRKPAHLILDELEVPYDDYVVVKHIGLLTSTLIAKIINGVTLFNATAVEDLIVKEVKGVATNWALVTKAHGTQNCMDPNTLLSVLVSVCGHDGPHGATGIKRLHQGMKALHMNSAEDAIVANTKEIPGFIIAGMEVSEACGTNRMGATFGAMIMSGRKAGYLAR Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 FAPIRESQVSRAMTRRYFNDLAESDVVIVGAGSCGLSTAFTLATKRPDLKIAIVEAGVAPGGGAWLGGQLFSAMVMRKPAELFLNELGVPYEDFVVVKHAALFTSTLLSKVLPNVKLFNATTVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINALVISTTGHDGPFGAFSVKRLVSGMRGLDMRTAEDAIVKRTREIPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEAM Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 FAPIREADVSREMTTRYMNDLAECDVVIVGGGPSGLTAAYELSKH-PNLKVALIEASVAPGGGGWVGGQLFSAMVVRKPAHNLLDELDIPYDEYVVVKHAALFTSTIIAKVINGVKLYNATAVEDFIIRTVGGVVTNWSLVTKAHGTQSCMDPQVIEAVTISSCGHDGPFGATGVRRLAEGMRALDMNASENDIVEHTREIPGMIITGMEVAEATGTARMGPTFGAMMISGQKAAQIAL Conpu1 FAPIEEAQVSRAMIKRYFNQMAVSDIVIVGAGSAGLSCAYHLATSRPDLKITILEANVAPGGGAWLGGQLMTPMVVRKPADRFLTEIGVPFEDFVVVKHAALFTSTVLSRVLPNVALMNAVAVEDLIVRRVAGVVTNWTLVALNHDHQSCMDPATITAVIISATGHDGPMGAFSAKRLVSNMRGLDMERAEPAIVNGTREVPGLVMTGMELSEHDGSNRMGPTFGAMMASGIKAAKEAM Copci FAPIEEAQVSRAMIKRYFNTMAISDVVIVGAGSAGLSCAYSLATQRPDLKITIVEAGVAPGGGAWLGGQLMTPMVIRKPADAFLRELGVPYEDFVVVKHAALFTSTLLSKVLPNVVMMNATAVEDLIVHRVAGVVTNWTLVALNHDTQSCMDPNTITAVIVSATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNGTREVPGLILTGMELSEHDGSNRMGPTFGAMIGSGHKAAHEAI Croqu1 FAPIKEHQVQRAMVRRYFKDMAISDVIIVGAGSAGLSCAYALGKARPDLKITILESNVAPGGGCWLGGQLMSAMVCRKPADEFLDEVGVPYEDFVVVKHAALFTSTVLSKVLPNVKMFNATACEDLIIKRVAGCVTNWTLVSLNHDHQSCMDPSTITAIVCSFAGHDGPFGAFCVKRIASDMRPLDMERAEDHIANKTREIPGLIVGGMELSEFDGSARMGPTFGAMLLSGRRAAEVAL CryneH991 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 FSPIRESQVSRAMTRRYFTDLAESDIVIIGAGSCGLSAAYMLGKARPDLKIAIIEAGVAPGGGAWLGGQLFSAMVMRKPADAFLADLGVPFEDFVVVKHAALFTSTILSKVLPNIKLFNATAVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINAVVISTTGHDGPFGAFSVKRLVSGMRGLDMQTAEDAIVKGTREIPGLIVGGMELSEIDGANRMGPTFGAMALSGVKAAETAL Debha1 FTPIRESTVSRAMTSRYFADLAESDVVIIGAGSAGLSAAYILAKNRPELKIAIIEAGVSPGGGCWLGGQLFSAMILRKPAHLFLEELGLEYEDYVVVKHAAFFMSTLLSKVLPNVKLFNATAVEDLITRRICGVVTNWTLVSLNHDTQSCMDPNTINAVILSASGHDGPFGAGSAKRLDKHMRGLDMNSAEDAIVKGTREVPGLVVTGMELAEVDGSNRMGPTFGAMALSGVKAAEAVL Dekbr2 FAPIRESQVSRAMTSRYFKDLAESDIVIVGAGSAGLTCAYVLAKSRPDLKIAIIESNVAVGGGCFLGGQLFSAMVLRKPADRFIKEIGLDYEDFIVIKHAALFITTICSKVLPNVKLFNATAVEDLITRRVAGVVTNWTLVSMHHDDQSCMDPNTINAVVISCTGHDGPMGAFCVKRLATRMGCLNMNLAEDAIVKNTREVPGLVCAGMELAECDSSNRMGPTFGAMIQSGVHAAEVAL Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 FAPIEEAEVSRAMIKRYFTTMAISDVVIVGAGSAGLSCAYHLAKTRPDLKITILEANVAPGGGAWLGGQLMSPMVVRKPADRFLQEIGVPFEDFVVVKHAALFTSTILSKVLPNVVLMNATAVEDLIIRRVGGVVTNWTLVALNHDTQSCMDPNTITAVVISATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNRTREVPGLIMTGMELSEHDGSNRMGPTFGAMMASGIKAAHEAI Fusgr1 FAPIRESQVSRAMTRRYFQDLAESDIVIIGAGSCGLSAAYILGKKRPDLKIAIIEASVSPGGGAWLGGQLFSAMIMRKPADAFLREVGVPYEDYVVVKHAALFTSTIMSKVLPNIKLFNATCVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINALIISTTGHDGPMGAFCVKRLVSGMRGLDMNLAEDAIVKGTREIPGLIVGGMELSEVDGANRMGPTFGAMALSGLKAAEEAL Galma1 --------------------MAISDVVIVGAGSAGLSCAYRLATDRPDLKITIIEASVAPGGGAWLGGQLMTPMVIRKPADRFLREIGVEYEDFVVVKHAALFTSTLLSKVLPNVVLMNATAVEDLIIHRVAGVVTNWTLVALNHDTQSCMDPNTITAVIISATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNGTREVPGLILTGMELSEHDGSNRMGPTFGAMIASGVKAAKEAA Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 FGHIRESQVSRAMTRRYFEDLAESDIVIVGAGSCGLSTAYVLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVLRKPADRFLDDLGVPYEEMVVIKHAALFTSTLLSKVLPNIKLFNATCVEDLITRRIAGVVTNWTLVTLHHDDHSCMDPNTINALVISTTGHDGPFGAFCAKRLVSGMRGLDMNSAEEAIVKNTREVKGLIIGGMELSEIDGWHRMGPIFSAMMLSGVRAAEVAL Klula1 FAPIREATVSRAMTSRYFKDLAVSDVVIIGAGSSGLSAAYVIAKNRPDLKIAIIEANVAPGGGCWLGGQLFSAMIMRKPADKFLDELNIPYEDYVVVKHAALFMSTVLSEVLPNVKMFNATAVEDLVTRNVAGVVTNWTLVTQNHDTQSCMDPNVIELVILSCCGHDGPFGAFTVKRMASGMKGLDMNRAEDAVVKNAGAYGSVYFAGMEVAEHAGLNRMGPTFGAMAVSGIKAAEDIL Lacbi2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 FAPIEEAQVSRAMIKRYFNMMAISDVVIIGAGSAGLSCAYHLATTRPDLKITIIEANVAPGGGAWLGGQLMTPMVVRKPADRFLTEIGVPFEDFVVVKHAALFTSTVLSRVLPNVVLMNATAVEDLIVRRVAGVVTNWTLVALNHDTQSCMDPNVITAVIISATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNGTREVPGLIMTGMELSEHDGSNRMGPTFGAMMASGIKAAREAI Malgl1 FADIKESHTSRAMISRYYKDMSVSDVVVIGAGSAGLTCAYKLAKSRPDLRITILEAGVAPGGGAWLGGQLQSAMVIRKPAHNLLVELDVPFDDYVVVKHAALFTSTILSKLLPNVKLFNATCVEDLIIKRVNGVVTNYTLVSMAHGLQSCMDPQTITAIICSFAGHDGPFGAFTVKRLASDMNPLNMNESEGLIVNNTREVPGVVVGGMELSELDGHPRMGASFGGMLASGTKAAVEAA Mellp23 FAPIKEHQVQRAMVRRYFNDMAISDVIIVGAGSAGLSCAYALGKARPDLKITILESNVAPGGGCWLGGQLMSAMVCRKPADEFLDEVGVPYEDFVVVKHAALFTSTVLSKVLPNVKMFNATACEDLIIKRVAGCVTNWTLVSLNHDHQSCMDPSTITAIVCSFAGHDGPFGAFCVKRIASDMRPLDMERAEDHIANKTREIPGLIVGGMELSEFDGSARMGPTFGAMLLSGRRAAEVTM Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 FNPIKEADVSREMTRRYMTDMAETDVVVIGAGSAGLSCAWELSKN-PDIQVTVIEQSVSPGGGAWLGGQLFSAMIVRKPGHHFLAEVGVPFEDYVVVKHAALFTSTILSKLLPNVKLFNALAAEDLIVKRVAGVVTNWTLVTLHHDTQSCMDPNVIEAVVVSSTGHDGPMGASGVKRLQKGMIALDMNAAEDGIVANTREVPGMVITGMEVAELDGVPRMGPTFGAMMLSGQKAAHCAL Mucci2 FAPIRESQVSREMVTRYMNDMAESDVVIVGCGSAGLSCAWELSKD-PSLKIAIIEQSVSPGGGCWLGGQLFSAMVVRKPADKFLDELEIPYEEYVVVKHAALFTSTILSKLLPNVKLFNATAVEDLIVKKVAGVVTNWTLVTLNHNTQSCMDPNVMEAVIVSGTGHDGPMGASGVKRLESGMLSLDMNAAEDDIVKYTREVPGMVVTGMELAELDGAPRMGPTFGAMLISGQKAAYAAR Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 FSPIRESTVSRAMTRRYFADLAETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAWLGGQLFSAMVMRKPADVFLDEVGVPYEDYVVVKHAALFTSTVLSKVLPNVKLFNATTVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINAVIISTTGHDGPFGAFSVKRLVSGMRGLDMQSAEDAIVNNTREIPGLIVGGMELSEIDGANRMGPTFGAMALSGVKAAHEAI Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 FAPIRESQVSRAMTRRYFQDLAESDVVIVGAGSCGLSTAYVLAKARPDLKIAIVEASVSPGGGAWLGGQLFSAMVLRRPADAFLTELGVPFEEFVVVKHASLFTSTLLSKVLPNVKLFNATCVEDLITRRLAGVVVNWTLVTLHHDDHSCMDPNTINAVIVSTTGHDGPFGAFCAKRLVSGMRGLDMNAAEDAIVKNTREVKGLIIGGMELSEIDGFNRMGPTFGAMVMSGVKAAEETL Phybl2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 FAPIRESTVSRAMTKRYFADLTESDVVIVGAGSAGLSAAYVLAKNRPNLKIAIIEASVSPGGGCWLGGQLFSAMVLRKPAHLFLDELEIQYDDYVVVKHAALFMSTLLSKVLPNVKLFNATAVEDLITRRIAGVVTNWTLVALNHDTQSCMDPNTINCIVLSTTGHDGPFGAFSAKRLEEGMRGLDMNKAEDAIVKGTREVPGLVIAGMELAEVDGSNRMGPTFGAMALSGVKAAESVL Plicr1 FAPIEEAQVSRAMIKRYFNTMAVSDVVIVGAGSAGLSCAYHLATTRPDLKITIIEANVAPGGGAWLGGQLMTPMVVRKPADRFLETLGIPFEDFVVVKHAALFTSTILSRVLPNVVMMNATAVEDLIIRRVAGVVTNWTLVALNHDTQSCMDPNTITAIIVSATGHDGPMGAFSAKRLVSNMRGLDMNKAEPAIVNGTREVPGLIMTGMELSEHDGSNRMGPTFGAMMASGIKAAREAI Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 FAPIKEHQVQRAMVRRYFQDMAISDVIIVGAGSAGLSCAYALGKARPDLKITILESNVAPGGGCWLGGQLMSAMVCRKPADKFLDEVGVPYEDFVVVKHAALFTSTVLSKVLPNVKMFNATACEDLIIKRVAGCVTNWTLVSLNHDHQSCMDPSTITALVCSFAGHDGPFGAFCVKRIASDMRPLDMERAEDHIANKTREIPGLIVGGMELSEFDGSARMGPTFGAMLLSGKRAAEVAL Punst1 FAPIHEAEVSRAMIKRYFNMMSISDVVIIGAGSAGLSCAYHLATTRPDLKVTILEANVAPGGGAWLGGQLMTPMVVRKPADRFLQELGVPFEDFVVVKHAALFTSTILSKVLPNVVMMNATAVEDLIVRRVAGVVTNWTLVALNHDTQSCMDPNTITAVIISATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAIVNGTREVPGLIMTGMELSEHDGSNRMGPTFGAMMASGVKAAKEAI Rhior3 FAPIRESQVSREMVTRYMNDMAESDVVIVGCGSAGLSCAWELSKD-PSLKIAIIEQSVSPGGGCWLGGQLFSAMVVRKPADKFLDELEIPYDEYVVVKHAALFTSTILSKILPNVKLFNATAVEDLIVKKVAGVVTNWTLVSLNHDTQSCMDPNVIEAVIVSGTGHDGPMGASGVKRLESGMLSLDMNAAEDDIVRYTREVPGMVVTGMELAELDGAPRMGPTFGAMLISGQKAACAVR Rhoto1 FAPIKEHIVSRAMSSRYGKDQAISDIVIVGAGSAGLSAAYAIAKERPELKVTILEAAVAPGGGAWVGGQLQSAMVVRKPGHYFLDELNVPYEDYVVVKHAGIFTASCLAAVLPNVKLFNATAVEDLISRRIAGVVTNFTLVTMAHGLASCMDPQTITAVVMSFAGHDGPFGAFSVKRLVADMRTLDMRQAEDFIVNNTREVPGLVTGGMELAELDGSSRMGASFAAMFVSGIKAAKIAI Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 FAPIRESTVSRAMTSRYFKDLAVSDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKPAHLFLQELEIPYEDYVVVKHAALFISTVLSKVLPNVKLFNATCVEDLVTRTVAGVVTNWTLVTQAHGTQCCMDPNVIELVILSTTGHDGPFGAFCAKRIVDGMKGLDMNHAEHDVVIHSGAYDNMYFAGMEVAELDGLNRMGPTFGAMALSGVHAAEQIL Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 FAPIEESQVSRAMIKRYFNTMAVSDVVIIGAGSAGLSCAYHLALNRPDLKITILEANVAPGGGAWLGGQLMSPMVIRKPADAFLRQLGVEYEDFVVVKHAALFTSTLLSKVLPNVVLMNATAVEDLMIQRVAGVVTNWTLVALNHDTQSCMDPNTITAVIITATGHDGPMGAFSAKRLVSNMRGLDMNRAEPAVVNQTREVPGLIMAGMELSEHDGSNRMGPTFGAMIGSGVKAATEAI Schpo1 FAPIRESTVSRAMTRRYFSDLAESDIVIVGAGSAGLTAAYYIGTRRPDLKIAIIEASVAPGGGAWLGGQLFSAMVVRKPADLFLNEIGVPYEDYVVVKHAALFTSTVMARTLPNVKLFNATAVEDLIVKRIAGVVTNWTLVSLNHGLQSCMDPNTINALVVSATGHDGPFGAFCVKRLASDMRPLDMNRAEDLIVKGTREVPGMIVGGMELSEFDGANRMGPTFGGMMFSGIKAAQEAL Sorma FSPIRESTVSRAMTRRYFADLAESDIVIVGAGSCGLSCAYVLSTLRPDLRITMIEAGVAPGGGAWLGTAL---------------------QRAQACRR------------LPNVKLFNATTVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINAVIISTTGHDGPFGAFSVKRLVSGMRGLDMQSAEDAIVNNTREIPGLIVGGMELSEIDGANRMGPTFGAMALSGVKAAHEAI Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 FAPIREADVSREMTTRYMQDMADVDVVIVGAGPAGLSAAYEFTKH-PEIKVALIEASVAPGGGAWVGGQLFTPMVVRKPAHLVLDELNVHYDEYVVLKHAGLFTSTILSKVINNVKLFNATSVEDLIIRTVAGVVTNWALVTKAHGTQSCMDPQVMESIVISSCGHDGPFGATGVRRLEEGMRALDMNAAEDAVVAKTQEIPGMIVTGMEVAEACGTARMGPTFGAMLLSGRKAALLAL Sporo1 FAPIKEHITARAMSRRYGDDLAISDIVIIGAGSAGLSAAYTIASRRPDIKVTILEAGIAPGGGAWVGGQLMSAMVVRKPADKFLTEIGVPFEDYVVVKHAALFTSTILSKVLPNVKLYNATAAEDLITRRVCGVVSNFTLVTLAHGLQSCMDPQTITALVLSFAGHDGPFGAFSVKRLVADMRCLDMRSSEDYIVNNTREIPGLITGGMELSELDGANRMGASFGGMFNSGKKAGLEAI Stehi1 FAPIQEAQVSRAMIKRYFNQMAVSDVVVVGAGSAGLSCAYHLGKTRPDLKITILEANVAPGGGAWLGGQLMTPMVVRKPADRFLTELGVPFEDFVVVRHAALFTSTILSRVLPNVVLMNATAVEDLIIRRVSGVVTNWTLVALNHDTQSCMDPNTITAVIVTATGHDGPMGAFSAKRLVTNMRGLDMNKAEPAIVNGTREVSGLVMTGMELSEFDGSARMGPTFGAMMASGVKAAKEAM Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 FSPIRESQVSRAMTRRYFEDLAESDIVIIGAGSCGLSTAYVLGTQRPDLKIAIIEASVSPGGGAWLGGQLFSAMVMRKPADAFLREIGVPYEDYVVVKHAALFTSTIMAKVLPNVKLFNATCVEDLITRRIAGVVTNWTLVSMHHDDQSCMDPNTINALVISTTGHDGPMGAFCVKRLVSGMRGLDMSRAEDAIVKNTREVPGLIVGGMELSEIDGANRMGPTFGAMALSGVKAAEEAL Umbra1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 FAEIKESHTSRAMTARYMADMAVSDVVIIGAGSAGLTCAYTLAKQRPDLRITMLEASVAPGGGAWLGGQLMSGMVIRKPAHNLLVEIGVPFDDYVVVKHAALFTSTLMSKLLDNVKLFNATCCEDLIIKRVNGVVTNWTLVTMAHGLQSCMDPQTITAVVIGACGHDGPFGAFSVKRLSSDMRPMDMNKSEGLIVNNTREVPGLIVSGMELSEHDGHPRMGASFGGMIGSGQKAAYEAI Walse1 FAPIKEYETSRAMTTRYFNDMAISDVLIIGAGSAGLSCAFTIATERPDLKVTIVESAVAPGGGAWLGGQLLSAMVVRKPGHNFLDKVGVPYEDYVVVKHAALLTSTLLAKTLPNVKLFNATACEDLIVKRVTGIVSNWTLVSLNHDTQSCMDPNTITAITISFCGHDGPFGAFSVKRLASDMRALDMNKSEDQIVNQTREVPGLIVGGMELSELDGAPRCGASFGGMFGSGVRAAYTAI Zygro1 FTPIRESTVSRAMTRRYFQDLAVSDVVIIGAGSSGLSAAYVICKNRPDLTVTCVEANVSPGGGAWLGGQLFSAMIMRKPAHLFLDELEVPYDDYVVVKHAALFTSTVLSKVLPNFKLFNATAVEDLVTRTVAGVVTNWTLVTMAHDLQSCMDPNVIELVILSTTGHDGPFGAFSAKRIVDGMKGLDMNHAEADVVKNSGSYGSVYFAGMEVSELSGCNRMGPTFGAMAVSGIKAAEEIL [Cluster3504.fasta_al_trimmed; alignment length = 83] Allma1 ----------------------------------------------------------------------------------- Ashgo11 IVCNDPPYPSHVAEHHKNMITERMLQLHLQELHDPF-------NSNK-ALECYFQTHSKRREHLITVHEYPMN-ARLDIVYTG Aspfu1 ----------------------------------------------------------------------------------- Aurde31 LMCYLPPLEAHYARVHKVFPDARLLELHHTECHDPLAAMRKE-RGEK-IFRCHCATAKTRRLHLIEAHHYPKQ-YFFAITNRG Batde5 IRCNLSPYEDHYELVHRVLPTAHLLHLHLQEFHDSFFKVLAE-TQV--AFECFSKTSNARIRHLIKTHGYPQD-FDFRIV--- Botbo1 -------MEVHYATYHKIFPDERLLDLHFSECHDPLTAVRKE-RGER-TFSCHFQTPKGRRLHLISAHGFPKQ-Y-------- Botci1 MRCSLPGYEVHYKKSHKNLPSEHFLNLHIEENHDALVSVRKD-RGEK-IYSCFCSTPQKRRMHLIDKHMFPQQ-YDFFVVNDG Caeel ----------------------------------------------------------------------------------- Canalb1 ILCNYHPYHLHVVSIHKVFPNKSFLSLHIDENHNPLLQIKQE-RGDK-IFKCYFSNPKERKHHLIEIHNYPID-YPFNIVNDG Cangl ----------------------------------------------------------------------------------- Capow LQCQVPGYESHYAAIHRVLPTDRLLSLHLLELHDSMFAVMAE-R-QP-MFECLFINPDERHVHLVEIHRYPAT-FDFSVARRG Catan2 ----------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------- CocheC53 MKCSLPPHDVHYHQVHKNFPDQHYLHLHIAEYHDPINAAKRD-QGEK-TYACLCSTPQKRRLHCIDKHQFPRE-YDFIVVKDG Coere1 -------FEKHYDQMHAALPSAHWLDLHIQEYHDAFFRARVA-RSEK-PYRCFFSRPHKRIMHMVDKHHFARS-FNWKLVRTG Conco1 ----------------------------------------------------------------------------------- Conpu1 ----------------------------------------------------------------------------------- Copci HMC----VGAYFQKLV---------------VHSSLKP----------QFACHFATPKARRLHLISSHGYPKE-YFFAVTNKG Croqu1 FTCSLSPLESHHRTHHLVFPDERFLNLHFRECHDPLLQLARE-QGKK-TFACFFLTPKSRRLHLIDSHGYPST-FHFSLPNHG CryneH991 YPCTLPPLERHHDIFHKVFPEARLLDLHYTETHDPIARERQK-NGEK-IFECFFTNPKNRRLHMISKHKYPTQ-YFWSITNHG Crypa2 IQCSLPGYEGHYNTVHRNFPTSHVLDLHILEQHDALAKIRRE-KGEP-IYACFFKGIGKRQDHLIMSHKYPAN-YFFAVTKFG Debha1 INCSIPPYEAHIVDTHKKFPSETFLDIHIDENHNPFFQISKE-KGEK-VYKCFCIDRRKRRLHMIDKHAYPRN-FNFGVVDSG Dekbr2 ----------------------------------------------------------------------------------- Dicdi IKSKIKHYENHYHSIHKSYPTYKLLECHILETHDKLFELKKK------MFECFFWSDYSRKLHLVDYHKYPKD-FYFHSKQRS Dmel -------IRDNIDKEQKMLPTAHLLDLHITEQHDCYFAASVE-RGDKPMFSCFFHTARQRKDHCIITHKLPAN-YRFDHSKNR Enthi YQCDF--MECHMRLNHRNFSNEKYLDIHLCEVHDSFFKLVHP------SYQCYSLTNEERTNHMKLVHHWNNI---------- Falba ----------------------------------------------------------------------------------- Fomme1 LFCSLPPLEVHYAKYHAVFPNIRLLELHQTECHNPLALIKKE-RGEK-IFACHFLDPKKRRLHLIQAHGFPKE-YFFAVTNKG Fusgr1 MRCNLPPYEVHYNKSHKNFPTEHLLNVHIEEYHDPLVTVKRE-QGEH-TYSCFCMTHQKRRMHLIDKHMYPKN-FFFAVTKDG Galma1 LLCNLPPLERHYATYHCVFTDARLLELHQTECHDPIAALRKE-RGEK-IFQCHFLTPKARRLHLIQAHSYPKE-YFFAVTNKG Ganpr1 IRCTLHPYEKHYTRVHRTLPTPRLLEIHVQECHDSWFAVRAG-RGES-MV--------------------------------- Gloin1 IVCCLPPYEIHYNTSHKLFPSERWLNLHFAEFHDIMAQMRKE-KGEK--------------IH-------------------- Hisca1 MRCSLPPYEVHYAQEHKNFPTGHFLTLHIEELHDPIIVSRRE-RGEK-TFSCFCSTSRKRRLHLIDKHQFPRL-YNFSIVNTG Klula1 VLCSDPPYPSHVSQMHRNFASEYWMELHIEEFHNPF-------KNGNYRLRCLFSNSNERIDHLKRHHYYSDQ-FDFDILNSG Lacbi2 LLCSLPPLESHYAKYHCVFPDARLLELHQTECHDPLAAVRKE-RGEK-IFACHFLTPKARRLHLIQAHSYPKE-YFFAVTNKG Lenti61 LLCTLPPLEQHYAMYHCVFPDARLLELHQTECHDPIAAVRQE-RGDK-IFACFFSTPARRRQHLIQAHGYPKE-YFFAVTNKG Malgl1 ----------------------------------------------------------------------------------- Mellp23 -----------------IFPDERFLNLHFRECHDPLLQLARE-QGQR-TFACFFHTPKTRRLHLIDAHHYPPT-Y-------- Mnele ----------------------------------------------------------------------------------- Monbr --------------MHRAFTTAHFLDLHQSEWHDPFFDLQKQ-RQP--MYRCFMASRNERREHLIQAHHYPPS-FPF------ Morel2 HHGSCHGYEHHFETNHKAFPGEKWLILHIREIHDVLVRIQRE-RGER-IYQCYCMTPQKRRMHLIDKHHYPKH-FNFSIVVTG Mucci2 --------------VHKIFPGEEWLQLHLDEFHDVILQLKKD-RGDK-IYKCYFSTPRMRRLHLVDKHHYPKY-FPFDLVYTG Mydma FKCSIK-YNQHFDLLHRHLPSNHLLELHLMETHDTYFQACLE-KGLE-VYQCFFVNEETRKKHLVDIHHYPAD-FKFSVSKRN Neucr2 MKCSLPPYESHYNSIHKNFPSSHLLGLHIEENHDSFTAVKRD-KGEH-TYSCFCMTPQKRRMHLIDKHMYPKN-FFFAVTLHG Orpsp11 IKCNLLPYEAHYSLTHVTLMTERLLNIHLQEVHDSFFEVLSQ-R-KN-MYQCLFKDAEERKIHLMEKHNFSKL------TN-- Pench1 MHCSLPPYEVHYLQSHKNFPTGHFLNIHIEENHDPLAAARRA-RGDK-TYGCFCSTPQKRRLHLIDKHMFPKT-YNFYIVNDG Phybl2 EHHSCHHYELHYEAKHKVFPSSHWLQLHLDEFHDVLKKIQKE-RGEK-IYACYFIDPRLRRLHLIDKHHYPKY-FPFDIVLTG Picst3 IECTIPPYETHILSFHRRFPSEKFLHLHIDENHNPFVKIEQE-KGAK-VFKCFCSTPKKRRLHMIDKHGYPRL-FRFDVVNRG Plicr1 LLCTLPPLEAHYASHHTVFPDAWLLQLHQTECHDPIAAVRKE-RGEK-IFACLFRTPKGRRLHLMQMHAYPDK-YFFAVTNKG Polpo ----------------------------------------------------------------------------------- Pucgr2 YTCNLPPLEAHHRTHHRIFPSQFFLDLHLNEVHNPILLVQRESRQTK-IFRCFFSSPKTRRLHLVDFHGYPQT-FFFSLPNQG Punst1 LLCTLPPLERHYATYHCVFPDERLLELHQTECHDPLAAVRKE-RGEK-IFACHFATPKARRLHLVSAHGYPKQ-FFFAVTNKG Rhior3 ----------------------------------------------------------------------------------- Rhoto1 PARSRPRTASTMPSYRRVFPDERMLQLHLTECHDELAQLKHE-RGDK-IFACFFSTPKNRRLHLIAQHGYPSQ-YYFSVTVWG Rozal11 ----------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------- Schco3 IVCSLPPMEAHYAKYHLVFPDERLLDLHFTECHDSLAATRQA-RGDK-IFECFFAHPKARRLHLIDIHKYPKQ-YFFAVTNKG Schpo1 ----------------------------------------------------------------------------------- Sorma MKCSLPPYESHYNSTHKNFPSAYLLGLHIEENHDSFMSVKRD-RGEH-TYSCFCMTPQKRRMHLIDKHMYPRN-FFFAVTLHG Sphar FNCGEPGYEHHYNSSHQSLPSERVLELHISETHDPFFKVLNL-R-QP-MYECFFMAENDRRQHLVVTHQYSSNCLDL------ Spipu1 VSCTLAAYREHYREAHRILPTAYLLDIHLQEMHDSFFQVLAA--QQD-MYRCLSSTAQSRNHHFSHSHSLNKE-YDVRVVFGE Sporo1 ----------------------------------------------------------------------------------- Stehi1 LYCTLPPLESHYAKHHCVFPDARLLELHQTENHDPVAEVRKE-RGDK-IFACFFSTPKTRRLHLIQVHGYPKQ-YFFAITNKG Tapde11 LTCTLPPFESHYQKYHARFPTNIFLDLHLEECHDPIWSARLA-RGEK-MFRCFFGSATSRRRHLETVHQYPSE-FRFNIVTKG Thetr ----------------------------------------------------------------------------------- Treme1 FICTLPPLERHQENFHKVFPEARLLDLHRIETHDPLARERKN-KGEK-IFECFFANPQKRRRHLIDKHKYPEQ-YFFSVTNHG Trire2 MRCSLPPYEAHYHKFHKNFPTNHLLEIHIEECHDPLAKVARE-KGEH-TYSCFCMTPQKRRLHLIDKHMYPKN-FFFAVTKEG Umbra1 DLTLCKGYEIHYEKWHKSFPGEEWLEMHFDEFHNVLNQISKE-KGEK-IYKCYFSTPKMRRLHLIDKHHYSKL-YPFDLPFTG Ustma22 ----------------------------------------------------------------------------------- Walse1 ----------------------------------------------------------------------------------- Zygro1 IICQEHPYTEHVQQYHGNFVTEKLLEIHQEECHNPF-------RQKS-SLRCFFNTQDQRIDHLLKEHNYPNT-FDFNIISRG [Cluster3517.fasta_al_trimmed; alignment length = 167] Allma1 LKDLQDAAQVKTAAEP-LKDKKGLSFLEVKNHCMMTYLTGLCHVKLGGQAPPAL-DSLLDLRVIMEKIKPMETKLKYRIDKLL--KATGASDALSFKPNVANFVYRPPKLAPVHY-DDADRQAYEEEHMLRVNWTRADKKKRSQLERTNELLNL-TA--RSLHRTVG Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 LGEMTKSMAAQESVKN-LLSTDGISLLSLKHHLMLSHLQGLTLLRVLGESIDVV-DTLLENQVVLDKIKILESRMKYQIDKLV--RLAIGEDPLAFRPNPTTLVYRPPKVAPVPY-IEEHMTRFEEDNMTRLVLAKRDDKRRRRDEEEDDFADLLLDRARDVKASKR Batde5 AKGIQAKIEVRSRIAP-LIENHGVSLLEVRVHSLLSYITNLSYLKLNGRSIPVV-DRLIELRTVLEKTKPLEQKLAYQIDKLV--KAAMIKNPLSFKPNPSALVYRPPRVAPMRY-DDREREEFEEENFIRLNLSKKD-KRIERTMQQNEFQDLVVGKRKHFSNRKS Botbo1 ANEMAASMSVRETVQT-LAKKSGISLLSLKDHTLLSYLQSLVLLRMLGHSLDLV-DSLVESRIILEKVKILETKMKYQIDKLV--RMAVTDDPLAFRPNPQNLVYRPPKLAPMPY-NEDRMTRFEEENMTRLVLNKKETLRRKRDEAAEEFGDIVLERSRDIKTMKK Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel VAELETQTEAVKAFSK-VFDR-GLSLLKLKNYEMTAYLGELTVLMMKGESIPSV-KRALKHRVFIEKMKPVEDKMKPQIEKLLGRSSA----------------YVAPRIRAVRY-EERERERYEEDNFTRIRLNKDQKRRSEQLGRGDYMMRG--NKR---EGRKR Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 LAEIRAAAQARQAIPK-IESQHGLSLLDVKNHCLITYMSGLTHLKIAGEPSLSL-DTLLEMRVLLEKIKPMESKLKYRIDKLL--KMGAAAGALSLKPNLTDFVYRPPKLAPVHY-ESAERQRYEEDNFLRMNLTRADKKMAKQRGRSDEVKELGTAKNRKLRKAAA Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 LDAMRTQAQVRELVDK-LRQRNGLSFLETKHHTMLSYISELAYIKLHGQQLPVV-QWLIEDRMVLEKMRPLEQRLRYQIDKLL--RNAAMADPSAFRPNPSSLIYRAPKQIPVHY-EEEEKARYEEDNFTRLAVGKKERKGMRKRLAEDEF---------------- Conco1 LESIGTQVAISDKLTV-DFEA----------SLLLEYITLLSYYKLTKQSIPLL-LKLIKIRAYLEKIKPLETKMKYQIDKLI--KAATVDDPYMFKPNPNLLVYKAPRIAPMPY-DDMERETYEEDNFIRLTQSKKQKKKIERLNQHNELLDFVTNKQRSMKKKMN Conpu1 -------MSVRSSIQT-LREKDGISLLSLKHHLLLSYLNSLVLVHAIGDSLDLV-DSMIEGRVALEKIKVLESRMRYQIEKLV--RLSLANDPLAFKPNPQNLIYRPPKLAPMPY-VEDRMREYEEENFTRLVMKKKDAKKRARDEAEDEFADVVLSRAKQRVALSK Copci LQSMTNSIASRTALKSMLDESDGISLLSLKHHALIAYVRSLALIRALGHTLDQV-DATIENRIVLEKISALENRMRYQIEKLL--KTVVVNDPLSFRPNPANLVYRPPQLAPMPY-IEKRLTEYEEENFTRIVTKKSEAKRRARDEAEDEFGDVVFSRSLEAKAAKK Croqu1 LKTIQ---ESTRLLAQ-IPNDDGISLLGLKNNVLLAYTHHLINIRLSGPT---V-EQLVWLRLVMDKVRPMEGKLKYQVDKLV--KKAVVNDPLAFRPNPAALIYRPPRLAPMAY-PDARMDEYEETNMTRLVTSKKESRKRRADEEESEFADVGRKVSKAVRKSVK CryneH991 FGTIQTAVATTSSSTP-LLNKNGLSLLNLRPHLLLSSLHQLVILRLASSTEEIA-GELVMNQEVMDKVRGLENKLEYQIKKLV--GLAVEEDPLSFRPNPSAIVYRPPRVAAVPY-SEKRIEEFEEENMTRLVTSKREAKRRRDDEAEAELEGVALERGKELARRRK Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel LGEMNSNVQVTDLVEG-MLQRYGLSFLEVKYHMLLDYLINLTYVKCSGETIPSI-ERLIEIRTVLEKIRPIDHKLRYQIDKLV--KTA---DPILYKPNPDDMVYVPPRIKPVYY-DGKEKQEYEETYLMRLPVTKAEKHRQRKLTTGDEIL-G---------GKKR Enthi MKALRENVELANKINV-LNMKKGISFLDVKYSLLFEYNMYLAYYKSSGSNVKAI-ERLFYLRILMERCKPIEKKLKYQIDKLL-----IADESLNAKPNVDDLVYKPTTIAGKAMEVEKEIRKYEEQMHVRLNKKQKLTK-------RDEFQELIVDDNEEIDSDEI Falba MAELAKQLQIRAHLAP-LADRNGVGFLDAKYQLLLSYCADLVHYKASGRSVETL-ASLIKTRIYLEKIRPLENKFKYQIDKYI--KAASAADALSARPNVMNL-----KSAALQSATSRARTEHEEATFTRLQVTRKDR-ARLK---SD-LRDLVAQVAKRLREQIR Fomme1 ---MTSSVATRESVKK-ILAQDGISLLSLKHHLMLSYCQALVLLRVLGHTLDLV-DSMIENRTVLEKVKALESKMRYQIEKLI--RLAIVNDPLAFRPNPQNLIYRPPKVAPMPY-TEARMTEFEEENFTRLVMKKKDSKRRRRDEEEDEFADVVLSRSKDQAALKK Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 ---MTKSLAARAALQS-IKRDNGISLLSLKHYMLVSYLQSLVLVRVLGNTLDLL-DSMIENRIVLDKTEVLESKMRYQITKLV--RITTTDDPLAFKPNPMSLIYRPPRLAPMPY-VEKKLKDFEEDNFTRLVMKKNDAKQRARDEEDDEFSEVAFERSLETKVAKK Ganpr1 --------------------------------------------SSSKKQKEVITASKASTLPY----RP--PRF--------------APTVTTAKPSRRGT---------------KEKEKFEEEHFVRLPTSRKERKARMELAKRDELESLLAASSKKVKKLVK Gloin1 INELKLKIEVKEQLSS-ITSRQGISLLEIKYHTLLEYITSLTFIKLNGQSIPVV-ENLIELRVVLEKLKPLEQKLKYQIDKLI--RATALSNPLSFKPNPQDLIYKAPKLAPVHF-EEEERLRYEEENFIRLSLSKKELKRLKKNTTEDEFENLVLNKRKNFKRQKR Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LETMSTALSAREALSS-LDKQDGISLLSLKHHTMLSYMRSLALVRVLGHSLDLV-DSMIEGRVVLEKIGALESRMRYQIEKLL--KIAMFDDPLDFRPNPQNLIYRPPRLAPVPY-VAKRLKDFEEENFSRLIMKKSDAKRRARDEEADEFGDVVLSRSLDAKIAKK Lenti61 LDQMKVSMAARDIVKT-LREREGISLLSLKHHMMLSYLQSLSLLRAIGHSLDRV-DAMVEARVVLEKVKVLEGRMKYQIDKLV--RTAIANDPLAFRPNPQALIYRPPKLAPMPY-VEKRINEFEEENFTRLVMKKKDARRRALDEADDEFGDIVLARSKEVKAAKK Malgl1 AAQLRKDSDSAQLVQK-LSESEGLSLLTAKVDALLAYIQNLALLRLSGNTL--V-QNLVRLRLRLEKMRPMEARLKYQVEKLL--QAAAADEDLSFRPNPEGLVYRPPKVAPMVYDPDRRMQEFEEDNYKRLSLNKKDAKRRRRDEQEEEFGDLTAQAKKAMRKQRQ Mellp23 LKTIQ---ESNRLIEQ-LPTEEGISLLSLKNDILLSYIHHLINIRISGPT---I-EQLVWLRLVMDKVRPMEGKLKYQIDKLV--KKVVINDPLAFRPNPAAMIYRPPRLAPMAY-PDARMDDYEESNMIRLVTSKKESKKRRADEAESEFADVSR-VSKAVKRSSN Mnele LSSISKHSEFDEAVAK-VKEVNGISLLDLKNQTVLNYLISLLTLKVEGKDI-VR-WNTIVNRTVLERIRPLENKLHYQIEKLM--RVS---DALNFKPDVEDLLYKAPRIAAAHY-YEKDRTEYEEANFMRMSLSKSERKKPRIQSG-NNILDL-----KSFRGKKS Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LKELATMLEIESKLKP-TIAKKGLSFLEVKYHILLEYITNLAFVKLDGQSIPAV-VSLIEQRTILEKMKPMEQKLKYQIDKLV--RAAGGADPLAFKPNPKNLLYRAPKMAPVHF-EEREREDYEEANFTRTMLSKKEINRLRKGALENEFENLVLARRRNIGRSKS Mucci2 IKSLKAKIDMKNQLKP-LKQKKGVSFLEVKYQVMLQYILQLAYFKISGKQLPVV-ESLVELRVILDKMKPIEAKLKYQIDKLV--RAAVAADPLAFKPNPMNLVYRPPKLAPVNY-DEAEKDRYEEDNYVRLAVTRKEKQRLNKNKKESEFDNLVLNRKSKKKGGRP Mydma LTTLDAQIDSIPYINS-LQEKDGMSYLETKCHLFLEYLIDVAYLKMDGKSLSCV-ERLVRTRTILEKIRPIDKKLTYQIDKLI--KMA---HPLSFKPNVDDLVYVPPKVTAVPY-DDEERRCFEEDNLRRLTLTKKDKKNLKELNS-DEAVKI-----KKFKKRMQ Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ---------------------------------MLSYVINLAYFKLDGQKIPVI-LQLIKERTILEKMKPLELKLKYQIDKLV--KMAELQDPLQYKPNPKNMLYRPPKIVPMHF-EELEKQKYEEENFMRFTLTREEKKARKRMNKQDEFNNLILRKR-------- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 LQDLKAKTELKTQLQP-VMQKKGVSFLEVKYQIMIQYILQLTFYKLSGKQVPVV-KSLVELRVILDKMKPIEVKLKYQIDKLV--RTAVANDPLAFKPNPMNLVYRPPKLAPVNY-DAAEKSQYEENNYVRLAVTRKEKKRMQSKNKESEFD--IMTRV-------- Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ---MTRSMSVRETIKS-LRDKDGISLLSLKHHVMLSYLQSLVLLRAAGHSLDLV-DSMLEGRVVLEKVKALEGRMRYQIEKLV--RVAVIDDPLAFRPNPQALIYRPPKLAPMPY-TEARMNEFEEENFTRLVLKKKDAKRRQRDEEEDAFGDVVLERSKEAQSLKK Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LGQIS---ASSQLSSQ-LAELGGISLLELKNHLLTSYLHNLTNLRLSQTSH-IV-QQLVWLRLVFERLRPLEARLKYQIDKLL--KTVVMNDPLSFKPNPAALVYRPPRVAPVAY-PEARMNEYEEANMTRLFSTKKDAKRRRNDEAEGEFDGVKNKNSKALKKISK Punst1 ---------------------DGISLLSLKHHLMMSYLNSLVLLRLLGHPLDLI-DHMNEDRVILDKIKFLEGRMRYQIDKLV--RLAVVDDPLAFRPNPQNLIYRPPKLAPMPY-TERRLTEFEEENFTRLVMKKKDANRRLRDEEVEEFSDVVLERAMDIKSAKR Rhior3 VKDLKAKVDMKNILKP-LKEKKGVSFLEVKYQLMLQYVLEIAYIKISGKKIPVI-ESLVELRVILDKMKPVENKLKYQVDKLV--RAAVAADPLAFKPNPMNLVYRPPKLAPVAY-NEAEKNKYEEENYVRLAVTRKEKQRMNANKKESEFE--VKNRK-------- Rhoto1 LGEIKSGVAVKDSADG-WKQRSGISLLSLKNHLLLSYIQHLLALKLQGRSLDVV-AQLVKLRVVLEKMGPLEQRLKYQVEKLV--RKAVLNDPLAFRPNPSNLVYRPPRLAAMPY-VEDKILDYETSNFRRLGKSKKDERDRRRMEEGAEFDDLGFKRPKAVKRANS Rozal11 FVDFKKYLEIRNTLEP-LMTRKGLSFLEVKYQLLLSYCTNISFYKARGKRVPVI-DRLVELRIILEKMKPMEMKLKYQIDKIL--KSS---DPLQFKANVDNLVYKAPKIAPMHF-NDKEKLLYEEENFNRLILSKKEMKKLNSKQKRNDLSQLMIAKRKKLKTVRS Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro LEPIVPAIDAIAQVKE-LQQDNGVSFLELKNQVLLDYIANLTLLKLRGKSIDVV-DRLVMLRVVMEKIKPLDKKLKYQIDKIV--KLA--DDEMQFKPNPTNLVYQPPKIAAMPY-TARQIQEYEEDNFLRLNVGKKQKKRSNPRNS-------VKRKSKMMEAQKT Schco3 LEEMKSSMSVRELIGS-LRNDDGISLLSLKHHIMLTYMQSLALVRVVGHSLDLV-DSMIEGRIALEKINILEGRMRYQIEKLV--RLAVADDPLAFRPNPQNLIYRPPRLAPMPY-NPNRLTNYEEENFTRVVMKKRDALRRVRDEEEDEFGDVLLERSLAAKSVGK Schpo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar IQEYTGKVKATHHVRA-LTERKGMDFLHSKLHANLSYCISTAVLKAEGESIDIV-KELVRLRGYIEKMRPMESKLKYQIDKLV--KMSEANNALSYRPQLSSL-------------DE-----------------------------------------KSISSQHR Spipu1 LSDFKAKVELRARLAV-TIDGNGVSLLEVKVHSILSYLTNLAFYKLHGHSPEAI-SNLVELRIVLEKIKPLEQKLKYQIDKLV--KAAALQDPLAFKPNPAAMVYRPPKLAPMHY-DEAERERFEEENFIRLNMTRED-KRLAANLRQDEFQALVLQKQKEVKKRKR Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 MDEMTSSLSVREQLKL-LREKEGISLITLKHHLLLSYIQSLVVLRALGHSLDLV-DSMIESRLVLEKIKVLETKMRYQIEKLV--RVAALDDPLAFRPNPQALIYRPPKLAPMPY-TEKRMTEFEEDNFTRLVLKKKDDKRRRKDEEEDEFTDVALARAKEVRTGRK Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LSDVQVSAATSSALRP-LMEKSGLSLLLLRPHLLLSSLHHLVILRIQG---EII-RELSVNREVMDKIKGLEGKLEYQIKKLS--ALAVEDDPLSFRPYTSAMVYRPPRVAAVPY-TEARMNQFEEENMTRLVTSKREAKRRREDEEEAELEGVVLDRAKDVAGHGK Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 MKDLESKIEVQNQLKP-ILQKKGISFLEVKYQLLLQYIANLAFIKLSGKQVPVV-QSLIELRVMLEKMKPVEQKLKYQIDKVV--RTAAVSDPLAFKPNPMDLVYRPPKLAPVTY-DEQEKDKYEENNYVRLAVTRKEKKRLQNNNRDNEFDNLVMNRRRHMK-SKS Ustma22 FGTIRKSVTSVKAFEK-DANEDGISLLSVKNDVMLDYLHHVIALKISGRSL--V-QDLVKLRLMLEKLRPLENRLKYQMDKLL--RAAASDDDLAFRPNPSAFVYRPPKLVPMSYDPDARMEEFEEDNFTRLVMSKKDARKRRRDEAEEEFGDLTLQRSNQVNRARK Walse1 LQTIQQSVSVKGVIEA-LNNTNGLPILTAKCHTLTQYIHDLIHLRLRKSSIDIV-DDLIKLRVIHEKSRNLSTKMRYRIDKLV--SAASV-DPLAFKPNPSALVYRPPKLAAVPY-TDQHMQDYEEENFTRLVQNRKDANRRLRDEADGEFDDVALDKARQVGDAAR Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3523.fasta_al_trimmed; alignment length = 229] Allma1 SLRSFGKPAAKKVAVIQQQALEQDAT--AFDYDGVYDAMKDREARKAVNKDD--KRPKYMENLIRSAQVRKI-DRLRAQETKYKRERADEDDEFADKEAFVTGAYREALEEVRRMEEEEARR---DGMAAFYRTFLDRTDADHKAGVDPAAVAVNASGEVVDKRQLLGAG-LNVPKTKELLD------QKRRADEERREEEALAKQSTE-QTVSDARARYLARKAAAAA Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 KL-SYGLN-LRSSKKHAEDAQQLDPT--IYSYDAIYDSLHAAKSDAKAASADAKDGPRYMTSLLRSAEIRKR-DQLRARDRLLAKEREAEGDEFADKEKFVTSAYKAQQEELRRIEQEEAERERQEGMVGFYRDMLSRDEQRHEEVVKAAEIAINDEGEIVDKRQLLSAG-LNVARQTEMIARQLEEKARQEAEAEAARQRETRTRKTE-TDVLSAKERYLARKREREE Aurde31 KL-SFSLN-TKAEKKKIAAELKVDNT--VFQYDEVYDAMKDSEARKARKEDEEKRKPKYISGLLATAETRRL-DRLRADEKLYQREREQEGEEFAGKPSYVTDGYLAQVQETRAAEEAEKAREGMSGMAHFYKTLLDQNEAVHSAAVAATSVELNDDNQIVDKRDLLNAG-LNLERRRREVEQQWQEERERMLAEKRREEEEIRRRNDD-EAIQSARERYLARKKRKLE Batde5 PL-QFGLN-VAAVEIAEQLAKESDPT--LFDYDTAYDYLKEASLIQRQRDGANDKKPRYIEALLSASSKRKI-ELERAEERKIQREREEDGDKFGEKDMFVTEAYLQRKEELRKIEEEEKRKEETE-MTGFYKNILERQEADAVDKIAALAIIMNDFDEIVDKRQLLAGG-LNLNRSAKASLQQQEQKKQEAAEEAEQNKARAASKVSD-IQVQSARDRYLARKKADES Botbo1 KL-SFSLA-SRAERKRMEEEKAIDNT--VYEYDAVWDRMKDAERHKEAREEESKRKPKYIKNLLNSAATRKL-DHLRAEEKMMQREREAEGDEFADKEKFVTQAYKDQMAEVRRAEEEEKRREEEEGMTHFYRTLLERSDEQRSAAVAATSVELNDDNQIVDRRQLLNAG-LNLERQARLIERQLEEENERAIREKEAEEEELEKRNNE-AEIQRARQRYLERKKRKLE Botci1 --------------------------------------------------------------------------------------------------------------------------------------MLEKGEQKHAEIVKAAEIAINDEGQVVDKRELLKGG-LNIERQSRMMEAQLEQATKRALEEEEEEKQKSKSRKTE-GDIMSAKERYLARKREAEE Caeel ---HVGLN-QKAAEREHQKAEAEDPT--IFDYDGNYDEIQAIKNEEEARKADKNRESKYAENIIKAHARRQL-EQFSREERQQLREREKEGDEFDDKEVFVTGAYRKQQEEVKKHREQEAEEAAFNGMG---RTLLNDLARDPTAKQRKKEPQKNFEGD-------LKPG-LNTEKSEKAPKISLKDKLKPKKIDKEARLDGLKQRNTE-EDIEAARQRYFERKEQGIV Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -----------------------DAH--VFDYDGVYDAMKARESQKSAKQAQ--KGPRYMEALLRSAEIRKL-DHLKAQTTKYKLEAAADKAEFGETEAFVTSAYKESLEQIKRMEEEQERKAAEDGMSAFYRNFLDRSDDSRGA---PSAVRVNDSGEIVDKRSLLVAGALNI----AVLDVQ---IQKRKAEEDAAERERLAKKANE------APCRMHER------ Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 SF-KFGLN-AAEAEKRAQEALEVDAT--IYDYDAAYDAIHAQDAAAAADREDAARKPKYMDALFESAEQRKK-DQLRARDKLLQREREAEGDEYADKEKFVTGAYKAQQEETRKAEEEEKKRLEEEGMQGFHKQMLAERERRHQEAMEAAAVVLNDDGQVADHRQLLSAG-LNVERQTAMVVEQIEAANKRKAEEEAEEQAKRKSQKTD-QDISSAKERYLQRKREAAA Coere1 SL-KVGLN-TRESAKLASELETSDPT--IFAYDELYDSISSNSQHRDSRSSQKSSRPRYMEKLIETAKQRKV-HAEVAREKMLAKTREREGDEFADKESFVTAAYKEQKEQRQRLVEEEEAKEKEMGPAAFSRQFLDRVEQEGAKAILAGVTSNNDSSNHESKDVALSAG-LNIGTSDKPMWADVESHEREKLAAQDRERQLYSRRNND-ASIDAARQRYLERKQARL- Conco1 KL-KYGLN-SQKALASSKVEIDLESN--IYDYDSVYDAMKLAQKREDKLRGEDEEGPKYFEKMVQSSNQRKL-ERKLAEEKMIQKEREREGEEFKDKEKFVTEAYKKQMEELKKFEEE--------NIQSFYKQMLDKDSAIREA---AINVLLNDDRQIIDKRELLNPG-LNV---RKYITKQLEEREQNVKLEEEEQKKTLKRKNND-ESLMSAKERYLARKKAKEA Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci KL-SFSLK-SKAMQKRIEQEKAVDPS--VYDYDEVWDRMQEVKEKKAAKAIEAMRKPKYIHNLLSSAATRKL-DHLRAEEKMMQRERELEGDEFKDKEAFVTQAYKEQLAEIRKAEEEEKKREEEEGMAHFYRKLLEESAQQHEATMKAAEVELNDDNQIVDKRELLAAG-LNLERRAREIRRQMEEEQRKAAAKKKEEEESVAKRNTE-EDVMSARERYLARKRQRLE Croqu1 GI-KFDFG-SRQQKQKQEEAAKLDPT--VFEYDQVYDDMKQAERQKLTKEQSGARKPQYISGLIETAKQRQI-DRVRAEDKMVQRERESEGTQFADKDAFVTPAYLEQQAELRKAEEAEKLKAEQGGMVSFYKNILDEQARRNDAAVKAV-VDLDDEGRIVDHRQLLTGG-LNMERQSLLLQQQLIELESNKRKAEEDKLNEVARRNDE-SKIEELKRKAQERRKAREK CryneH991 KI-SFSFG-SRAERRAQAAAQAIDQS--IFDYDSHYEQMKAAERVEEVKKKEGERKPKYIESFLASAQTRKL-DKLRAEEKMLEREREKEGDEFEGKEKFVTEAYKRQMEEVRKAEEEEKAREEALGLTAFYKTMLDSEESKHAAAVSATSVEINDEGEVVDKRSLLKAG-LNIERERRRLAEQMREVEERKRKEEEEEEARGESGEAE-RKRAEARERYLARKREREE Crypa2 GL-SFGLS-ALTSRKYAEAAQSLDPS--VYDYDAAYDSLKAAERQAEVKKESAQRKSRYMADVTKAAEQRER-DRGVAELKKIQREREAEGDEFADKEMFVTEAYKRKQEEDRKAEEEERKREEDEGMTGFHKELLDRDDQKRADMEKLAAVVVNEEGEVVDKRELLRGG-LNLERQTRMLEAQLEESLKRAREEEEEERKKSKSQKTA-TDISSAKERYLARKRAAEE Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 KV-SFSLS-SKAQLRRAEEAKKVDET--VFEYDEVWDKMQAAKERKEMKSKEATRKPQHINALLQSARIRKL-DRLRAEEKMIQREREAEGDEFADKEQFVTQAYKDQMAEVRRAEEEEKKREEAEGMSHFYRQLLEQNDQEHSATLSAVSVELNDDNQIVDKRDLLSAG-LNLERRRREIEQQLAKETERTAQEKEKERETVAKRNTE-EDVQGARQRYLERKRRKLE Fusgr1 GL-SFGLN-SLTSRKNAEAAAEVDAS--VYEYDTVYDSLKP----KQATKEDQEKRPKYMKNIIQAADIRKR-DALIAEEKKIAREREAEGDEYADKEKFVTEAYKKQQEENKRLEEEEKKREEEEGMSAFYRKLLDKDEQRHSDAVKAAEVAINEDGQVVDKRQLLRGG-LNVERQTHMMEQQLEESMKRSRDEEAAQREEAKSRKTE-GEISSAKERYLARKRAAEE Galma1 KL-SISLA-SKAMQKRMAAERRVDET--VYEYDEVWDKMQEAKQRQAAKEADLTRKPKYIHNLLSSAATRKL-DHLRAEEKMMQREREAEGDLYQDKESFVTQAYKDQMEEVRQAEEEEKRREESRGMTHFYRQLLEESSQKHEATVAATEVELNDDNQIVDKRDLLSAG-LNLERRAREIQQQLEAEHQRTEQSKKADERIVAKRNND-SDVDSARARYLERKRRKLE Ganpr1 GL-AFGLN-DRTRIELEKALEEVDPS--IFDYDAAYDDLKAAEREKKKKGAVEEKQPRYIGALLRAADQRKI-DLLQATERKIQREREAEGDEFGDTEKFVTGAYKQTIEDMRRTEEEERKRAESE-LTGFYRSLLDETTRVVEVTVKAAGVLVNDSDEIVDKRQLLAGG-LNIERTAAYVEAQRREVLEREREKREKEVQGTQRRTTE-TAAEEARRRFLERKNAVGG Gloin1 ------------------------NS--IF------------------------NNILFINLLTSFAE---------------KIEKDANG-----------------------------------DTTKFYRNILDQASTAKTAAIEASRVMLNDDDQIVDKRQLLSAG-LNIEKQSRELEEQILKTQREKEEEESKKQEEFARKADE-KTISDAKARYLARQKEKKE Hisca1 TL-SYGLN-LHSSKKHAQTAESLDSS--IYDYDAVYDSLHAKPSSAAATETSTS---KYMTALLRSAEIRKR-DQLRARDKQLQREREAEGEEYADKEKFVTAAYKAQQEEARRIEAEEAEREREEGMVGFYKNMLERDERRHEEVVKAAEIILNDEGQVVDKRQLLTAG-LNVARQTEMLATQLEERMRKEEEEREAKEKEMKSSKTA-GDVQSARERYLARKREKEK Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 KL-SFTLT-SKAIRKRIEAEKRVDNT--VYQYDEVWDKMQEAKQRKEAKEVDATRKPKYIHSLLTSAATRKL-DYLRAEEKMMQLERDTEGDEFKDKESFVTQAYKDQMAEVRRAEEEENAREELRGMAHFYRKLLEESEKNHDATVAATQVELNDDNQIVDKRDLLAAG-LNLERRAREIQQQLEAERERSQKEQRADEEAVAKRNTE-VDVESARERYLQRKQRRVE Lenti61 KV-SFSLK-SKSMKKKLEEEKRVDST--VFEYDEVWDKMQEAKLKKEAKEADSKRKPKYISGLLTSAATRRL-DHLRAEEKMIQRERELEGDEFKDKESFVTEAYKKQMEELRRAEEEERKREEEEGMAHFYRKLLEESEQQHEQTVAATEVELNDDNQIVDKRELLSAG-LNLERRAREIQRQMEEEQSRLKSEKEQEHESVAKRNDE-ESVKSAKERYLERKRRRME Malgl1 RL-SFSLK-SKQVRQQQEEAQQLDES--AFDYDGVYDQMKQVERDRQAKKEQDSRKPKYMNQFFKAAELRER-DRMRAESKMIQRERAAEGDAFGDKEAFVTSAYKEQQEEWRRAEEEERVREARE-VAAFHQKILDEECRHRQATVEALTVELNDDQQIVDRRDLLKRG-LNYSKRSQMMEEELL---------------------------------------SRMA Mellp23 AI-KFSIG-SRQQKLKQDEAAKLDAT--VFEYDEVYDDMKSAEKQKLAKEQSGVRKPQYISGLIETAKQRQI-DRVRAEDKMVQRERELEGAEFADKDAFVTPAYLEQQAELRKAEEEEKLKAEKGGMSSFYKNILDEDSKRNEAAVKAVAVDLDDEGRIIDHRQLLTGG-LNVERQSLLLQQQLIELESNKRKAEEDQMKDVARRNDE-SKVEELKRKAQERRKAREK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---GFGLT-DQEAQRDVEKALEEDDT--IFDYDEVYDSMNQERMRRFERFKEKKPKAKYINALMKSAAERKMVDELR-RERVAQKERDQEDGEFADKEEFVTEAFKKKLLELREFEAREKAEEEAEDLNSFYRTVLAQNDATTSAVSKAAS-----------------------QRQTEQMRAETAKRDQTQREEEAAMSEEYARQTSE-DQVDEARARALARRRQRKR Morel2 GF-QFGLNESTSVIEQQNAALAQDAT--VFDYDGVYDQLKAGDRAELARKQESARKPKYIHALLEAAETRKR-DRQIADEKRIEREREREGEEFKDKEQFITPAYKAQKEAMRVAEEEDRKKEEALLMQGFYRNLLDERSRMRPDGAGSLTVAVNEEGQIVDKDELLHGG-LNFSRMTEQIERQLLEQEKKREEEEKERQESLKRKNQD-DQVMDAKARYLARKAAAAA Mucci2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 GF-SFGL--ALESRKYAQAAATADPS--IYDYDAVYDSLKAPK--QEKEADSKEKRPRYFDALQKAAETRER-DRAIAEEKRLKREREAEGDAFADKEKFVTEAYKRQQEENRRLEEEEKKREEEEGLTDFYKQMLEKEEQEHAAKMKAVEVIINDDGEVVDKRQLLKGG-LNVERQTRMLEAQLEERLKRAREEEEEERKKSKSRKTE-ADISSAKERYLARKRAAEE Orpsp11 NI-SFGKN-SKQVEAEYKKAIEEDPN--VYDYDEVYDSMKRDELERKGKNQDKDKKPKYIASLLASAERRKK-EQMRIMERRIQKEREEEGDKYKDKEMFVTSAYKEQQEELRRLEEEERKREEQESMTGFYRNILNSRSHDPIKPLEDKNIALNDDNE---------------------------------------------------------------------- Pench1 NL-PYGLN-MHSSNVQAKAAEELDPL--VYSYDEVYDSLHAKPAKSVETKSDTP---KYMQNLLQSAEIRKR-DQLRAKDRQLAREREAEGDEFEDKEKFVTSAYKAQQAELRKAEEEEARREKEEGMIGFYRDVLSRGEARHEEVIKAAEVVVNDEGQVVDKRQLLSAG-LNVARQTDMVASQYEERARQEEEAEAAKQRESRSRKTE-KDVSSAKERYLARKREREE Phybl2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 KL-SFALP-SKAMKKRMEEEKKVDQT--VYEYDEVWDKMQESKLRKEAKEIDAKRKPKHIGALLNSAATRRL-DYIRAEEKMIQREREAEGDEFADKDAFVTQAYKDQMAEVRKAEAEEKAREAAEGMAHFYKKLLDESEKKHEEAVAAAAVELNDDNQIVDKRELLSAG-LNLERRAREIQQQMVQEQERLAAEKELDHEAIAKRNTQ-DDVQSAKERYLQRKRRKLE Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 TI-KFSLS-SRQQKLAQEEATKLDST--IFEYDQVYDLMKLADNKKLEKEQKGARKPQYISGLIETAKQRKI-DRVRAEDKMVQRERELEGEEFANKDEFVTPAYLQQQKELREAEEAEKLKAEQTVMTTFYQNILEEESKRHEAAVKAVAVDLDDEGRIVDHRQLLTGG-LNIERQSNLLQQQLLELENKKRKAEEDSRLEVAKRNDE-SRIEFLKQQALKRRQERQA Punst1 KL-SFSLG-SQAMKRRMEAEKKVDET--VFEYDEVWDKMQEAKARKLAKEEDAKRKPKYIGGLLATAQTRKL-DHLRAEEKMIQRERELEGDEFKEKEQFVTQAYKDQMAEVRRAEEEEKKREELEGLAHLYAQLLNESEQQHQETVAATMVELNDDNQIVDKRELLSAG-LNLERRRREIVKQMEEEKYRAREEREEEAERVAKRNTE-EDVMSAKERYLARKRRKLE Rhior3 -M-KFGLN-HKKLQEEHSKAIEQDPT--IFDYDAVYDDLKEAERKKEATKGPAEKKPKYIKGLLEMAEIRKR-DRLLAEEKKVAREREEEGEAFADKEVFITETFKKQKEELERIEREEKEREEKA-MDTFYKQVLERKEAEH--MLKAFAVMLNDNNEIVDKRQLLGAG-LNVERLSKEVEKQMMEVKQREQEEEERKKKATVKRTTE-DAAMSARERYLARKKQKLE Rhoto1 KL-SFGLN-TKAQKKKQQEEVELDPS--VFEYDEVYDNMKAAERVKEERKKESSRKPKYINRLLETAELRKQ-DRLRAEDKMIQKEREREGDEFADKDQFVTPSYLKQQEELRKVEEEEKKREEAEGISTFLKSYLDSTEAAHAAAVAATAVEINDEGEIVDRRQLMSGG-LNIERMSREIERQMLALEEKRKREAEEQLEQVAKRNDD-DRVAQLKAAAEERRKKRAE Rozal11 -M-NKGIS------KNVTKYNCGDTNDSIYYYDETYEDSK-----EVVRKES--KQPKYIEQLKKAAEDRKN-ERNKVIERKIQKQIASEQENI--TEKFITPAYKEKLLKAEREVEDERIKDDLE-MVMFYKGIINSLDAKPDD---------SDASIFVD------------PLSYKSLEKNLAHNNINRDVDVK-----LKTKNNDVATINNARERYLARKRMRMD Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 --------------------MAVDET--VYEYDEVYDKMQAAKQRKEAKEADAKRKPKYIEGLLTTAATRRL-DHLRAEEKMMQREREREGDEFADKEAFVTQAYKDQMEEVRRAEEEERKREEELGMAHFYRKLLEESETDHSAAVAATQVELNDDNQIVDKRELLSAG-LNLERRRREIQQQLREEEERRKKEMEEERARVAKRNTE-QDVMSARERYLARKRQREE Schpo1 GF-RYGLN-QITAASDASKDDNYDAS--IYGFDEFYDSMKSAEREMELKRLESKRRPKYMENLIESAKKRKR-DLLLARERALLKKNELEGDD--ATEKFVTSSYKKHREEVQKAIEDRKEEDEKSGMKDFYASMLDRQEKIHQAAVEGVQLELNDNNEIVDQRQILTAG-LNITYSLEEIDKQRKEFENRQRLQKESREAAASRNTTE-TQVQSARERYLQRKKKAAT Sorma GF-SFGL--ALESRKYAQAAADADPS--IYDYDAVYDSFKVPQ--KEKEADTKDKRPRYFDALQKAAETRER-DRAIAEEKKLKREREAEGDAFADKEKFVTEAYKRQQEENRRLEEEEKKREEEEGLTDFYKQMLEKEELEHAAKMKAVEVIINDDGEVVDKRQLLKGG-LNVERQTRMLEAQLEEKLKRAREEEEEERKKAKSRKTE-ADISSAKERYLARKRAAEE Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ALPKYGLI-SRLAEEEHKKALEEDPS--VFDYDAVYDDLKRAELEKKSKDNP-DKKPRYMAALIKASAKRKI-ELERAELRKVQREREEEGEQFGDKEKFVTGAYKQQVAELKRIEEEEKRREALE-MTAFYRDILNQSDRDPL----VINVQLNDSEEVVDKRQLLSGG-LNLARARELVLRQQQEKEEEDRKRKEREQEELARKTTD-ETVSDARARYLARKKAQAQ Sporo1 KL-SFGLN-SRAQRLKQQQELELDRS--AYEYDEVYDAMKSGQKSLDAIKQESSRKPKYISKLMETAELRKQ-DRLRAEDKMIAKEREREGDEYKDKEQFVTPSYLKQQEELRKIELEEKKLEGE-SITCLL------------------------------------------------------------------------------------------------- Stehi1 KL-SFSLA-SKTARKRMEAEKKVDET--VYQYDEVWENIQESRLRKEAKEVESKRKPKYINGLLTSAATRRL-DHLRAEEKMIQRERELEGDEFKDKDAFVTQAYKDQMEEVRKAEEEERQRDEAQGLAHFYRKMLEESESKHEETVAATQVELNENNEIVDKRDLLSAG-LNLERRRKEILAQM-EEQRRLETDQQEEREAVARRNDE-AAIQSALERYRARKRQKL- Tapde11 ML-SSGLN-------------NLDESDIAYDYDGVYDSMKSGEREKSKKEADKKRKPKYMQNLFQMAEIRKR-DRLRAEDVKLRREREAEGDEFADKEKFVTSAYKAQQEELRRIEREEDEKERILGFVAFNQNLLANDEERHDLAVSRTTIAVNDDNQIVDHRQLLGAG-LNRERQQRILDEQLRASNKRAAEESKAKEEQAKRSKTE-GDIKSAKERYLARKQAQGD Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 KI-SFSFG-SRSERKAQQDALSLDPT--AFEYDQVYDQLKASERAEQVKKIEAERKPRYIENFLASAQTRRL-DRLRAEEKMLQLEREKEGDEFDDKEKFVTEAYKKQMEEVRKAEEEERVREENLGLSAFYKTMLDDSAAKHAAAMSSTSVEMSDDGEIVDNRSLLKAG-LNIIREKKRLAEQMREDKLRREKEREEEEARGDDGEAE-RRRKEAKERFLARKRAREV Trire2 KL-AFGLN-TLSSRKNAEAATELDAS--VYEYDAVYDSLKP----KNKSKEDEERKPKYMKNLMKAADVRKR-DQLIAEEKKIAREREAEGDEFADKEKFVTEAYKKQQEENKRIEEEERRREVEEGMTSFYRKLLDREQERHAETVRAAEISVNEDGQVVDKRQLLKGG-LNVERQSRMLAEQLEASLKRSREAQEVKREEAKTRKTE-SEIMSARERYLARKKAAEE Umbra1 KM-KFGLN-NKKIEEQHKQALEEDPN--IFDYDAVYDDLKTAEKQQEQLKGKDNKKARYVEGLIEMAEIRKR-DRLRAEEKKVEREREEEGDEFGDKETFVTSSYKAQKEELRRLEAEERRKEEED-ITSFYRQMLDKREEAHAASIKGIAVVLNDDNVIVDKRQLLGAG-LNVERMSQEVERQMVERQERERGVQEEAGKA--------------------------- Ustma22 KV-SFGFK-TRTERKKQEEAEQLDAS--IFDYDGVYDIIKDAERKKQAKLAQDAKKPRYVDGILESAEQRKR-DRLRAEARTIQRQRQAEGDEFADKESFVTNAYKEQQAELAKAEEEQHKNEEMQ-ISSFYREMLNETNAARDAAIAA--VELNDDGQIVDRRSLLTKG-LNISRQSRLIEEQMLELERKRALEEDAQRRENAKRNDS-QAVLQAKQRYHERKKQRMA Walse1 ---------SSRLAKQLDEAKKIDES--VFEYDEVFDQMQAAREAESSRKKESARAPKYIEGLAHAAEKRKL-DRSRAEEKMIQKTREKEGDEFAGTEEFVTEGYKQTLAEIKKAEEEEEAREKKEGASAFMRGILNDKEEVHTAAMKAALVEIDDEGQAVDKVQLLSAG-LNAARHSKMVEEQMLSLSKQKEEERKATESQLERRNDE-SAIEAAKRRFAERRSKAGK Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3524.fasta_al_trimmed; alignment length = 63] Allma1 CAQIIEALEKCHKERKFFGACNDLKLQLNDCLTEDYKARRAVNAADARARRQRAEETWNELDL Ashgo11 CLDLVQALEKCHQADQAFGLCNPEKEALTQCLHNARLEGEKYHILANREKRKEMDAKWKQMQE Aspfu1 CEEIMTALDECHARGKALGNCNDIKRDVNKCLAAERYQRAKKNRDQARDNRKRIEKIWAEERA Aurde31 CKQFVEALEACHADPKWTFQCGGIKRELNMCLRALRVEKAEKNRAEGRIRKEKFQEALKDLHA Batde5 --------------------------------------------------------------- Botbo1 CKDMIIALHECHQTGRYLGGCNDLKHELNMCLRKERIERTTHNRERAKERRKTTVDAWRKIEE Botci1 ----MAALDECHARGKCMGMCNDKKTAVNKCLRAQRLARTAANREAAKVKNEKIKAKWAEIDE Caeel --------------------------------------------------------------- Canalb1 CDKLMDALEECHRQEQCLGMCNFEKEQLIQCLHYQRVEDSKLRILETREKRKNWELKKKQAEE Cangl CLDYIEALDKCHQKERMLGLCNNEKDALTQCLKQASAETKKKAIQENKLKRDKLESKWRKIEE Capow --------------------------------------------------------------- Catan2 CQEIIKALNECHATSKYFGACNDLKHKLNQCLTEDYVARRAVNAAEAKKRRDKAEKVWDELEL Cioin --------------------------------------------------------------- CocheC53 CADVVAALEECHAHGKVTGNCTDAKHKVNMCLRGIRLERTRQNREAAKEKRERIQKVWRELDE Coere1 CVELAEKLTNCHAENKFLGKCNALSEALNKCLGKEFEVRRKRQMIESRARWARIEARWHEMDM Conco1 CYEVIMNLSNCHLQNKFVGYCNSYKTELNGCLQEEFEVIRRAKYEKAKAKRERTEKLWKEIDE Conpu1 CREFIQALDACHASNRLTGGCNKEKLRLNECLHKESLARSSRNREHAKEQRLKTEQSWKELHE Copci CRDFIEALERCHASGRLTGACNSKKDELNRCLRTERVNRTTANREIAKEKNKKSENALKEFRA Croqu1 CGPIIDALDECHQRGYYTGGCNDIRRALDKCLHAERIKRSSEHVRKGKQNRKELERVWRENGS CryneH991 CAEFIQALEECHSRGRLVGVCNDQKAALGACLRKERLERTERNRDAAKERTAKKKAVWEALER Crypa2 CEDLMTALEECHDRGKSMGMCNGAKEALSACLRAERRKRQDNNRSKSQEKKDAIRQKWKEIDE Debha1 CEKLMDALEECHRQEKALGMCNFEKEELTKCLHYTRVNDANDRIRQSKEKQKKFEQRRKESEE Dekbr2 CSSLMRALDECQKKGKALGRCSSLRQELNMCLDQTTQARRRRKIIRKKAERKKFEEKKKKMFE Dicdi --------------------------------------------------------------- Dmel CNKLIEELQACHENNKFVGVCNSIDDKVVKCLKGERIARSAANRAKARERQAKYKEKLLQQES Enthi --------------------------------------------------------------- Falba CAEVINALQECHRTHRFFGVCTPLKESLSECLTQDYRMKQAENSAKARAKKEKMRKFNEELGI Fomme1 --------------------------------------------------------------- Fusgr1 --------------------------------------------------------------- Galma1 CKEFIQALEQCHAAGRFVGSCNKQKDELNHCLRSERLDRTAQNREQAKERKQKTDQALQEFRA Ganpr1 --------------------------------------------------------------- Gloin1 CLDVILRLEECHKSGKYFGGCNGIKKELNECLTLEYKEIRKKNADKAKENRKKVEELWKEFNL Hisca1 --------------------------------------------------------------- Klula1 CIDLIQALDKCHRKERALGLCNNEKEALSKCLHEARLSGERRYILESREKKKVIEQKWKKLEE Lacbi2 CREFIQALEDCHLSTRLTGGCNKKKDELNKCLRSERVARSANNRETAKERRIKADQALKEFHD Lenti61 --------------------------------------------------------------- Malgl1 --------------------------------------------------------------- Mellp23 CGPIIEALHECHQRGYYTGGCNDIRRQLDICLHAERMKRSSDHVREGKQKRKELEQVWRENGS Mnele --------------------------------------------------------------- Monbr --------------------------------------------------------------- Morel2 CEDIILQLDQCHNEGRYLGGCNKLKNAMNECLQAEFDVNRKKHFENAKEKRKKLEKAWEGMDE Mucci2 CDKVIEALEECHRAGKFIGTCNAAKRAVDECLKEEFLVMRAANKGKAQEKRKRMEAIWREIDE Mydma --------------------------------------------------------------- Neucr2 CHDVMVAFEECHARGKSMGMCNELKEELAACLRAERFKTQKINQSSVADKKAIIRQKWKEIDE Orpsp11 --------------------------------------------------------------- Pench1 CEEIMTALDECHAKGKALGNCNDIKVDVNKCLSAERYQRAKRNRDEARSNRRRIEEIWAKERE Phybl2 CYEAIQALDECHHANRFIGLCNDAKKKVDKCLKEEFVANRAAQKAATDEKRARMKKIWKEMEE Picst3 CEKLMDALEECHRQEQCLGMCNFEKDELSKCLHYTRVEDAKTRIRESRERNKKFEMKRKQNEE Plicr1 CKEFMQALEACHLDGRLTGGCNPQKDQLNKCLRQERIGRTTRNREQAKDRLARREEALKDLHE Polpo --------------------------------------------------------------- Pucgr2 --------------------------------------------------------------- Punst1 CKSFFDALEKCHADSYWTGGCNQIKHDLNMCLRQERLDRAAKNREDAKTRRAKAQAAWADLHR Rhior3 --------------------------------------MREANKGKSKEKRKKMEAIWKEMEE Rhoto1 CTEVMQALKQCHDANKFAGACNSQKHALNMCLREERLERTRKNQEAAKEKRKVVEQRWKELED Rozal11 --------------------------------------------------------------- Sacce1 CLDFINALDKCHQKERIFGLCNNEKDALNKCLKEASLNNKKRAVIESRIKRADVEKRWKKIEE Salro CAHLIKALRQCHEENKLMGACNEINSALDKCLKEAREAQRQKNLAKARKRKEALRKQREHQQ- Schco3 CKELVEALEACEADPKWTDKCSNIENLLNKCLIAARNNRSAQNREESKRKKAEFEKAKKDFWE Schpo1 CADLIRALEECHKS-KFFGECNTIKYELKACLTKDRNDKARLNRENARMRKKVIEENRKKEEI Sorma CHDVMIAFEECHARGKSMGMCNDLKEQLSSCLRAERFKNQKDNQSKVTDKKAIIRQKWKEIDE Sphar CQDAIDALEACHRENKFLGECNDAKTQLDRCLYDEYKVEQKRNLAESRRRRTAFKANMKESQE Spipu1 --------------------------------------------------------------- Sporo1 --------------------------------------------------------------- Stehi1 CLQLFEALEECHANAKWTGGCNQAKLDLNKCLHGDSVARAARNREDSKARQAKRDQAWKELHA Tapde11 --------------------------------------------------------------- Thetr --------------------------------------------------------------- Treme1 CAEYIQALEECHARGRYLGACNSQRRELVLCLRKERLNRTARNREEAKVRTAKKKEVWAALER Trire2 CQEVIAALEECHAQGKAAGGCNDAKILVDKCLRQQRSKVQEGNRAAAKAKRDRIKEEQRALGL Umbra1 CEHIIQALDDCHRSGKYSGKCNDIKLKLNECLGEEFQIVRAENKQKAAAKREKIRQVWKDMEE Ustma22 CAHLIQALNECHSKGKITGGCNGIKHDLNMCLRQERVERTANHVKESRESRKRTEQIWKQIEQ Walse1 CGDIIRQLYECREEGRILGGCQDIDKQLGKCLRDERIDRTKRNQEKAKVRNQKKQEAWSNL-- Zygro1 CIDFIQALDQCHQRERMFGLCDIEKEALSKCLHEARKNGEKEQIAIMREKRKALENKWKKMDE [Cluster3526.fasta_al_trimmed; alignment length = 159] Allma1 VAVVRQLEMMNLMLGFEQANAYTMKGGQDIGHIIEED-SLLLRNFLTTHRKMSAKVVNLQGEVVLPFNW-INSTIYIIGHVEQEWHLWRRRYNLFARIDAPILSWEFPLHDQVGMIDRNFTGFGRELFTDTGYAVHFLTLDERAAAAITIDFDYFS-RD Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 LVIQRQLELMNVMIGFEQANKYVIMDGNHIGYMAEQEKGMMARQWFRTHRSFVTHVFDRHENEVLPFSW-INSRIRVIGEAQQQWAPLRRKYNLFAYVDEPFLSWDFSLRSLIGSVNRNFVGFARELFTDTGYALRMMTLDQRAATAVSIDFDYFS-RH Aurde31 LFVTRQVEMLNIFLGFEQSNKYAINNGEVLGYIVEEPRGFIGRQVFRTHRPFRALVLDHDGAPILPFSF-INSRMYVFGVVQQRWHVWRRKYDLYAAIDAGFMAWNFPVADEIASVERNFRGFGREIFTDTGYAIRFLNLQERAALSINVDFDFFS-RH Batde5 LVVDRELGLVNMMIGIEQENQYSIKDGNDIGSIVEKSFSVIVKQILRTQSPFKADVLNSYGDVVLPTKWLLNSTITVIGKVKQKWHLYRRRYELVAKINGKPWTRNFGIENKLGLITRSFSGVIRELFTNIGYSIYMLTLDERAAAAICIDIDYFS-Q- Botbo1 LVVVRQIEMLNIFIGFEQANRYAILDGNNVGFIAEEDQGFFARQLFRTHRAFRSVIMDQNGNRVLPFSW-INSRLFVLGEGQQEWHPWRRKYHLFASINGGFWAWDFFLQDNIASIRRNFAGFGREIFTDTGYVIRFLSLEERAAMSVGIDFDYFS-RH Botci1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 LVIERQIEFMNLFIGFEQANRYIIMNGERIGYMEEKDVGFLGRQFFRLHRPFDIDVFNARGELAMPFSW-INSHIKAVGESVQSWHLWRRKYNLFGAVDAPFLSFDFPVKNVVASIDRNWVGLGREMFTDTGYILRYITLDQRASCFTSIDFDYFS-RH Cangl IIVERQLELMNVFLGYEQANKYAIMDGNKIGYMMERDFSIIMRQFYRLHRPFIVDVFDNWGNILMPFSF-INSHIKAVGETIQRWHVWRRKYDLFGEINAPFLSFEFPVLDIMGGVDRNWVGLGREFFTDTGYIIRFMNFDQRAANAVSIDFDYFS-RH Capow LIISRQIELANLLIGFEQANRYELRDGNQAGYLVEKK-TFIMRQILRLHRPFTALVLDTAGNPVLPFTL-INSTVYVIGFARQKWHLWRRKYELYGDVDMGLWSWVFDVRDLLARIDKDFSGLMTEMFTDAHYILKMLYFDERAACAVSIDFDFFS-RH Catan2 LGIVRKLEMMNLLVGFEQANQYAILNGHQVGYIVEED-SFLMRNFLHTHRRMNAMVLNAQGEPILPFNW-INSTITIIGAVEQEWHLWRRRYNLFARIDAPFLAWEFAMCDPVGIVDRNFTGLGRELFTDTGYAVHFLKLDERAAAAVTIDFDFFS-RD Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LIVQRQLEMMNVLMGFEQANRYVIMDGNHIGYLAEQEHGIVARQMFKTHRSFTTHVFDRDEKEILPFSW-ISSRIRVIGAAEQEWAPLRRKYNLFARVDEPFLSWDFSLMTLAGSVNRNFGGFAREIFTDTGYALRMMTLDQRAATAVSIDFDYFS-RH Coere1 LRVTRQLEMMNVFIGYEQANRYTLVDGNPTGFMVEER-TLIGRQIYRLHRPFKVLVLDLDGKVCLPFSL-INSRISVIGESQQEWHPWRRRYNLFARVDAPFLSWDFPMCNMVAGVFRDFAGIGMELFSDYGYAVCFLDLDQRAAAAVSIDFDYFS-RH Conco1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 LVVTRQLEMLNIFAGFEQANKYVITNGEQLGYIAEEPRGFFARQIFRTHRPFRAIVMDLEGAPILPFSW-INSRMFVFGEVQQEWHLWRRRYDLF-RVDEGLWAWHFNMRDVIASVNRAFRGFGREIFTDSGYFITFLTLDERASSAVNIDYDYFS-RH Copci LIVERQLEMLNIFIGFEQTNKYSISDGQPLGFILEEPRGFMTRQAFATHRPFKALIMDTHGTPLLPFAW-INSRMYVFAEVQQIWHPWRRQYDLFAKVDSGFLAWRFPILDEMAVIDRAFRGFGREIFTDTGYLVQFLTLDQRAALAVNIDFDYFS-RH Croqu1 IIIIRQLETLNVLIGYEQLNKYKILNGEIKGYIIEEENNRILRQILGTHRSFKSKILNENGIPLLPFHF-INSSIIIIGECQQEWNLFKRKYSLFGKIDEKFLSWEFFIKDILGKIDKIFKGFGREIFTDTSYLIDFLSVDQRAATTISIDFDYFS-RS CryneH991 LVIVRQLEMLNVFMAWLNKSK------------------VQSAGKLCEH----IVRLD----LLSPFAF-INSRIFVVGEAQH------------AKVDSGFLAWDFWLKDLLASINRNFRGIGRELFTDTGYVIRFLTLDQRAATAVSIDFDYFS-RH Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 LVIERQVEMMNVFLGFEQANKYKIMNGEQVGFMEEKDIGFLGRQFFRLHRPFDIDVFNNYGDLLLPFSF-INSHIKCLGESCQNWHLWRRKYNLFGAIDAPFLSFDFPVKNVIASVDRNWVGLGREMFTDSGYIIRMLTLDQRAGNAVSIDFDYFS-RH Dekbr2 IVIQRQIEFMNLFLGFEQANKYSVMDGNQIGWLIERDFGIIMRQVYRLHRPFTVDLLDNNGNLLSRFSI-INSHIKAVGESVQSWHLWRRRYNLFGKIDSGFLSWDFPVYNVVGDVSRNFGGLFREMFTDTGYIVRMLTLDQKAANAVSIDFDYFS-RH Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VILRRPMRWSNLLLDIDVAFKYSMDTLTPLGEAIEMSNGLLQRTLLKRRHWSHIRVQDFYGRDLFPFL--VNSVTRILGEVRQVWHLLSRKYDLYAHTDGGILAWTYPVQSLMTVTQRVFTALARELFVDQSFVVGM-NASQRLALAFAIDIDYFAFRH Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 --------------------------------MAKEPMGFLSRQAFATHRPFRAVILDC-----------LCGHVYI----------------------------------------------SRS---------------QRS----------LA-R- Ganpr1 --------------------------------------------------------------------------MFVIGEVHQIWHLWRRKYDLFARIDAPFLSWDFDIQGILGNVNRNFVGFAREV-------------------------------- Gloin1 LAVARQLEMLNVFLGFEQANKYAILDGNHVGYIVEEE-SFILRQLFRTHRKFNAMIMDLDGQLILPFAW-INSRIFIIGEVHQQWHLWRRRYNLFARIDAGFLSWDFNIEDVLGSVNRNFSGFAREIFTDTGYVIRMLSLDERAAAAVSIDFDYFS-RH Hisca1 LVVQRQLEMMNVLLGFEQANRYTILDGNHVGYIAERDNGMLARQWLRTHRSFVTHVFDKHQNEVLPFVW-VNSRIRVIGETHSQWALLRRKYNLFAYVDEPFLSWDFSLRSLIGSVNRNFVGFARELFTDTGYALRMMTLDQRAATAVTIDFDYFS-RH Klula1 IIIERQIEMMNVVLGFEQANKYAIMDGNRIGYMQERDFGFITRQIYRLHRPFTVDVFDNYGNVLMPFSF-INSHIKAVGESVQNWHLWRRRYELFGNIDAPFLSFEFPVMDIIAGCDRNWVGIGRELFTDTGYIVRFLNYDQRASNAVSIDFDYFS-RH Lacbi2 LLIERQLEMLNIFVGFEQANKYYICNGEPLGFIVEEDAGIVTRQAFATHRPFRAVIMDLQGSPILPFAW-INPRMFVFGEVQQVWHPWRRRYDLFAKVDSGFLAWDFRLYNEVVFISRSFRGFGREIFTDTGYSVTFLSIDERAALAVNIDFDYFS-RH Lenti61 LVVTRQIEMLNIFIGLEQTNRYAITNGETLGYIAEEPRGFFSRQIFRTHRPFRAIVMDTEGSPILPFAF-INSRMYVFAEVQQRWHLWRRRYDLFARIDNGFLAWHFTLRDAIANVNRAFRGFGRELFTDTGYFINFLSLEERAATAVNIDFDYFS-RH Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 LVVVRQLEMLNLFVGFEQANRYRILNGETVGFLAEENSGFLLRQIAGTHRAFQASILAVDGTELLPFSF-INSRISIIGEAQQEFHIWRRKYGLFAKIDAGLLSWEFFAQDLMGSVSRNFAGFGREIFTDTGYVIRFLTLDQRAATAVSIDFDYFT-RS Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LIMTRQIEMMNVLVGFEQANKYAIVDGEPIGYIAEEDTTMMSRQLLRTHRPFKASVLDLEGNEILPFAF-INSRIMIIGEVQQEWHLVRRKYNLFAHIDGGFLALDFDMQDPMASVNRNFVGFARELFTDSGYAVRFLTLDQRAACAVSIDFDYFS-RH Mucci2 LVVGRELEMMNVFLGYEQANRYKIMDGNHIGYIAEEE-GFISRQLLRTHRKMNATILNTQGEVAFPYSL-VNSRIFIVGEVQQRWNLVRRKYDLFASIDTPFLGWDFNLQDTLGNVSRNFVGFAREIFTDTGYVLRMMTLDERAACAVSIDFDYFS-RH Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 IVVQRELEMMNVMIGFEQANKYVIMDGNHIGYMAEQDKGLMARQWFHTHRSFVTHVFDRQENEVLPFSW-INSQIHVIGEAQQQWAPLRRKYNLFSYVDEPFLSWDFSLKSLIGSVNRDFAGFAREIFTDTGYAMRMMTLDQRAATAVSIDFDYFS-RQ Phybl2 LVVGRELEMMNVFLGYEQANKYKIMDGNHVGYIAEEE-GFLSRQFLKTHRRMNATILDAQGQVVFPISL-INSRIFIIGEVQQRWNLVRRKYDLFATIDTPFLGWDFTLQDTLGNVSRNFVGFAREIFTDSGYVLRMMTLDERAACAISIDFDYFS-RH Picst3 LVIERQIEIANVILGFEQANRYKIMNGEQIGYMQEKDLGIIGRQFFRLHRPFDIDVFNNYGDLLLPFSF-INSHIKCIGESIQSWHLWRRRYNLFGAIDAPFLSFDFPVKNVIASVDRNWVGLGRELFTDTGYIVRMLTLDQRAGNAVSIDFDYFS-RH Plicr1 LVVTRQIEMANIFLGFEQTNKYVISNGETLGYIAEEPRSLFTRQVLHTHRPFRALVMDLHGDPILPFTW-INSRMFVFAEVQQRWHLWRRRYDLFAVVDQGFLAWSFSLRDQVASVNRAFRGFGREIFTDTGYFVRFLTLEERAALAINIDFDYFS-RH Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LVIVRQLEMMNLFIGFEQANRYRILSGETLGFLAEEERGFLFRQIAGTHRAFQASIFDPLGAEILPFSL-INSRIFVIGESQQEFHLWRRRYNLFARIDAGFLSWDFFTLDPTASVSKNFTGFGREIFTDTGYVVRFLTLDQRAATAVSM--------- Punst1 LVVTRQIEMLNIFVGFEQANRYLISNGEPLGYIAEEPRGIFSRQLFRTHRPFRALVMDLEGSPILPFAW-INSRMHVFGEVQQRWHLWRRRYDLFARIDGGFWAWYFGLLDEFASVSRKFRGIGREVRT-SGYFIRFLTLDERAATAVNIDFDYFS-RH Rhior3 LAVCRQIEMMNVFLGYEQANRYKILDGNLLGYILEEE-GLISRQLLRTHRKMNATVINPEGEVMFPYSL-VNSRIFIVGEVQQRWHLLRRKYDLFATIDTPFLGWDFNLQDVLGNVNRNFVGFAREIFTDTGYVLRMMSLDERAACAISIDFDYFS-RH Rhoto1 IVVVRQIELLNVFVGFEQANRYQLLSGHLLGYLLEEETSIMSRQLLRNHRPFKAVVISPDGQVLLPFAW-INSRIYVIGETQQEWHIYRRRYNHFAKTDAGFLAWDFSVRDVVGSINRNFAGFARELFTDTGYVIRFLPLDHRAATAVTADIDYFS-RQ Rozal11 LVICRQIEWMRIVTGFDQANQYVIYDSNTIG---------FTRQIAGTHRPFEAFVLDLNSNVIMPFTL-INSKLTVFGLIHQK-----------ASINEGFLAWDFTLRDPLSYITRNWTNLAQELFTDAGYVVQFLTFEEKAGCSTAIDLDYFT-RY Sacce1 VIIERQIEFMNVFLGFEQANRYAIMDGNKIASMMERDFSIIMRQFYRLHRPFLVDVFDNWGNVIMPFSF-INSHIKTVGETIQNWHLWRRRYELFGKIDAPFLSFDFPVTDIMASVDRNWVGLGREMFTDTGYVVRFLTLDQRAANAVSIDFDYFS-RH Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 LIVERQLEMMNVFLGYEQANRYVILNGQHLGYIAEQGASSLSRQFFHTHRAFKADVMDSNGQLVLPFSW-INSRLQIVGEVLQKWHLWRRRYELFAKIDERVLSWEFLLRNILGSVSRNFMGLPREFFTDTGYVLRFMSLEERAGSAVTIDFDYFS-RI Sorma --------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 LMVTRQLEMMNVLIGYEQANKYAIKNGQDVGFIAEEETSFLARQFLRTRRPFKAVVLDQSGNVVLPLKWFLNSTILIIGEVTQVWHLWRRKYDLFAQIDAGFWAWDFHILDRIGEVNRNFVGFAREIFTDTGYAIHMLSLDERAACAVNIDIDYFS-RH Sporo1 ATVARQIEFMNIFLGFEQANKYQLLSGNLLGYLLEEEVGILRRQFLRTHRPFRATVLSPEGQVLLPFTF-INSRIYVIGEAGQVWNLIRRKYETFGSIDSGFLAWDFSVRDVIASINRNFTGFARELFADVGYVIRFIPLDHRAATAVSIDFDFFS-RH Stehi1 LVVTRQIEMLNIFIGFEQTNKYSIANGEPLGFIAEEPRGFFSRQIFRTHRPFRAIIMDREGTPVLPFDW-INSRMFVFSEVQQRWHPWRRRYDLFAKIDEGLWAWNFALRDEIASVNRQFRGFGREIFTDTGYFVNFLDLRERAAMAVNVDFDYFS-RH Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LVIVRQLEMLNVFLGFEQANRYAIYTGDLVGFLAEEERSFMSRQMLRTHRPFRAVVMDPTGTPILPFAF-INSRIFVVGEAQQEWHPWRRRYNLFARVDSGFLAWDFWLKDLVASINRNFKGFGRELFTDTGYVIRFLTLDQRAATAVSIDFDFFS-RH Trire2 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 LVIGRQIEMMNVFLGFEQANKYSIMDGNNVGFIAEED-SLMSRQLLRTHRKFNATIMNAQGEVVFPYSL-INSRIFIIGEVQQRWHLLRRKYDLFATIDTPFLGWDFDLRDLIGNVNRNFVGFARELFTDTGYVLRMLTLDERAACAVSIDFDFFS-RH Ustma22 LVVTREIEMINIFLGFEQANKYSIHAGELVGYLAEEEQGLLQRQVLRTHRPFRATVMDASGKPVLPFTW-INSTASIIGEVKQRWHLYKRRYELFAQIDAGFLSWTFLMQDLVGAIDRNFRGFGREIFTDTGYVLRFLTLDERAATAVSIDFDYFS-RH Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 IVIERQMEMMNVFLGFEQANRYAILDGNRIGYMQERDFSFMMRQFYRLHRPFTMDVFDNWGNVILPFSW-INSHIKAVGESIQNWHLWRRRYELFGQIDAPFLAFEFPVLDIMASVDRNWVGLGREFFTDTGYVVRFLNFDQRAANAVSIDFDYFS-RH [Cluster3528.fasta_al_trimmed; alignment length = 164] Allma1 MSLLASPATATTATLAQPPR-TWPQVRAEPPAPPELRFSTFTLGMFWGFLLGGAQHAGLQFLAENAHKLPVTVQGWYFYHKAKNYRSMWGAVKRGTVYAGRLGVVVGLFAVETGLDLAR-DLWSATAAGVVTATTFARLPRASVQRTLLYGTVTGLLVG-QPSS Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MDTDS-------------PTETEPSTLLKRLGIEVGRLPFTASAFSVGMAIGGSKKAAYRFRAENAHRFPTTSTGWFQYHKTKNYIAIVGGVKEGMKMGFKLSAGALAFIFEETVDYARRDFLSTVTAGLSFSGIYSRHDVYTAARTTKLGLKLSMAYGSKSED Aurde31 --------------------------------------YQLPLASTLGLTIGGSRKAGLQYLAENAHHPPRTVKGWYVYRQAKNNRMILGGLRQGVRDGVQMGVLAAAWAAE---------------------------------------------------- Batde5 MTTDNP---------------SYPSVIFTKHHIETSRLFF--GGIAAGFVSGQGHIRSRQFLAENAHRLPRTVGGWYFYHRHKQLAIISGAGVGGVYYAARFGLLSAMFVAEHAIGEWV-IFVNALGAGLFTAAAFSGLSWQASQRAFKYGGACGLLIG----- Botbo1 MDN-------SEDDAPASPA---------AIRIYIPRIYALPAATTIGLCLGGSRKASLRFLAENAHKRPTTIQGWYFYNKTKNYKVFLGGLKQGGIEALKLGTLGLGWGIQEGCTELG--EWKDLVAGGGTAMLVSRLPRTNTLQALAVGLLGGGAVSKKGDV Botci1 MK--------------AWRK-HHEALVLDRMSIPYGRLPLCTISFLCGMALGGSQAASLRFRAENAHRLPTSPTGWYLYHKSKNYNTGLGGVKEGLRMGGRIAFWTAGLAIEDMCDRWR-DVVNTVVASLSVAGGFSRFPIITAARTARTGLAFGIGYGPSPKD Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MSES--TITANSIDNPETDVR--------RFHLVPRRLEALVTSGLIGAMIGGVKISSLRYLTENAHRMPKTVGGWYFYHKKKNYVMIVAGVKKAITTSFKYGAAVGGFGLEYLLDISRIDFFNTTTAAFLTSTFYAKLSSMQTRKMIFKGTALGLTLG-TQQK Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ---------------------------------------------MWGFSLGGSRSAGLQFLAEHAHQLPVTVQGWYFYHKAKNYRMVWGGIKRGLWDAGRLGSVVAMFGVETAVDLAL-SAASGVVAGVTTAGVFARLPRASVQRTLMYGSIAGAFVGAKESS Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MASSA----PETDSTPPPPPPPYPT----SPRLDMPRLLLTTLSFLSGFTLGAGHMASLRFRAENAHRLPTSNPGWYLYHKSKNYYKWRYGIVEGLRKGTYIAAWSMVFVVEESLDVFRRDFVSSALAGMVTGGVWSQFPVSTAARTIRLGLLVGLGFGSLEKD Coere1 --------------------------------MSVGRMVTMTVSGGCGAVLGGAQQASRQYLAERAHRLPKTVEGWFFYHKWKNYRVTMGSVRGAFHYAPRLAGCVLMFAAEALLDRVV-QIANTVVASSATAIFVSQLPKSSARRARRAGLAVGLLVG----- Conco1 MTSTA-NPSGSQTITSTDPIS--------RAGLLTSRLFAMPFSTLLGFAIDGGKMASYRYRAEHQHKKPKSIQQWYFYHKTKNYKVILESIYKGSRMTAKLTALSCSFVLEYCGDFVTLPIVSSTLAGLVTATVVG--------RKFLYNIFIICFY------ Conpu1 ----------------------------------VARYFILPSAAGVGSLIGGSRLAGLRFLAENAHRPPTTIRGWYLYNKTKNYRRMAAALKTGGVDALRLGLIGLVWVIE---------------------------------------------------- Copci MDD--------EENATSTPA---------AIYLTIPRLYQVPGAASLGCAIGGGRAASMRFLAENVHRPPTTVQGWYFYKKTKNYRVMLGAIKGAAKEGGRLGAVSLLYGLEEGIQRLG-QHLSEVGAGGLTGGIFG------------------CGFG----- Croqu1 --------------------------------MERPSPILVPSASIVGFVSGSGKLSAAQFTCENLHRLPTSRREAYLFQKTKNYRIILGGLKGGLRSGARLGAWTGAFSLKELL----IPFTSSMTGCRSMAGALS------------------------PIL CryneH991 ---------------------------------------MLPAAGLVGLSIGGGSRARLRFLVENAHRKPKTVQGWYFYTKTRNYRVFFGALKAGGKYALGLGGATAGFLVDESVGWARAGEIQDVAQGGVAGGLMGKLPRPLFIRSLIMGIALGSLTSKPTEE Crypa2 ----------------MCDH-TYHGTTTNRLHLMAPRVILAASSFGVGAALGGSRMAGLQFRAEHAHKLPTTPTGWFMYHKSKNYNMARASVREAVRMGAKVSFWTTAMSIENLYDNYR-DFVNTVLASLTVAGGFSRFSLAMTARTTKTALVVGLVYGAP--- Debha1 SQEN--NNESSTART-DTDMR--------RFHLYPKRLQAVAVGGIIGAFSGGVSMASLRYLTENGHRLPRKVGGWYFYHKKKNYVMIMNGCKEGLKQGTKLSLTVTGFGLEAFFDTYVIDLLNTTAAAMITCGVYGRLSKVQTIKYVKRGALLGLSLGAKEDT Dekbr2 MESLNE-----------------------RLGLPPARVFSLATAAIVGSLGGGWKTSSLRYLASNSHRLPTTYNGWFFYHKRKMYYCLKQGMIVGFKTGAKLGGFVGCIAVEAGFDKLR-DFCNTMMAVCVPGVAYSRMPRVQANDFIRKGGRIGIGFG----- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 -----------------------------AIRLYVPRYMVLTVCGLTGLSLGGGRQEGMRFLAENAHRAPTTMRGWYLYKKTKNYRMMWGGLREGGREAVKLGVVGLAF------------------------------------------------------- Fusgr1 MAS-------PPDLDLAFPQ-AFP-----RLSVATPRLLLGTSSALVGFSLGGGQMAQLRFRAEHAHKMPDTTTGWYFYHKSKNYHAMQGGIREGFRMGFKTGFWSLLASLESTVDRYR-DMFSTTIATLTVAGAFSRLSLTTAARTARYGLMFGLAYG---RV Galma1 -----------NNDETKKP----------EIRLTIPRFMVVPTAFVVGSAIGGGRAASLRFLAENAHRPPTTVQGWYFYKKTKNYKVMLGALRGAGVEAGKLSGLALAYGLE---------------------------------------------------- Ganpr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ISSVSE-----------------------RANLTPYRITTTCLGGIWGFILGGAKRSSLQYLAERAHILPKTKEQWYLYHRNKNYKVILGAVKVGLPYAAKMSSLCFLYGLETTLDFIR-DIINSLIAGIISGTIVSQLPKQSTKYALMVGAGIGLITG----- Hisca1 MGSKQD---------SLPPIDTFSTILGHRLSIDPIRLPITVAAFTAGMVLGGSTRAAFRYRAENAHRLPTTTMGWYHYHRSKNYKSFVGGVKDGMKMGMKLGAGAFTFLFEETVDHARQDFLSTVTAGLAFSGLYSHHDAYTAARTAKLGLRLSLTFGSENES Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MLQ-------GNGDDEVAPR---------QIHLNVPRLVIVPTAIIVGIAIGGGRATSLRFLAENAHRPPTTVQGWYFYNKTKNYKVILGGLKGAGVDASKLGLMGLGWGIEEGMERLG--ECKEIGAALGTGAVF-------------------CGNRAWIDS Lenti61 MSS------AADVDDELN-----------AIRIDIPRYYLLPAAVLTGITIGGSRAASLRFLAENAHRTPRTVRGWYLYNKSKNYRVLLGGLKAAGADATKLGLTAAGWAVEEGCTHLG--DVREVAAGLGTGMLFGRMPMSAVRRTTVLGFLIGGVLREVVDG Malgl1 MGWWTT----KSSPQVAEPSG--------QRSLDVPRIIVPFSAMSLGFASGGARHTALVYLAENAHKRPTTVQGWYFYNKTKYYRMILGGFRHGGSTSLRLAGWVAGWLLDVLAE----DARSYLAAGSFANSFESKLGHWSD------GALAGFLTGSCTS- Mellp23 ------------------------------MDIEQ-SPVLIPSASIVGFVSGAGKLSGAQFTCENLHRLPTSRQAAYLFQKTKNYRIILGGLKGGLRSGARLGAWTGAFSMKEVT----IPIKSSIPHCRFIAGGISRLRPIYSPRRLMLGGLVGMLAGSEPQM Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 --MASQTSTPTTSNASQPGTGEAPKEHVSRIGLEPMRILLITSASFWGFMLGGSRQSGMQYLAENAHRLPKNMEGWYFYHKKKNYRMIWGALKKGAVYSSKTGAMVGLFVLEASLDFYR-DLFNSMGAGVASGGFFSKLPRQSTKHTLMLGAGYGLVSGPEPEE Mucci2 --------------------------------LATKRLVLMTIGSFWGFSIGGGRQSGLQYLAENAHKLPTTVQGWYFYHKTKNYRMMLGGVK----------------------------------------------------------------------- Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MST-------TKETEAAAP--PVPEYVTKRLSIPDARIPLASTALLIGFTLGGIKTAGMRFRAEHAHKLPTTKMGWYFYHKSKNYNSIWGGAKEGARMGAKICFWTTAMGIEHMFDAYR-DIFNTVTACVTVAGAFSRFSLPMAARTTKTALVVGLAYGQKERV Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 MGANH-------------PLSPHNSIVLKRLGIEFGRLPYATSAFSTGMALGGSKRAGLVFRAENAHRFPTTSTGWFQYHKTKNYIGVVGGVKDGMRMGLKLGAGALAFLFEETVDYARRDFLSTVTAGLSFSGIYSRHDVYTAARTAKLGLKLSLTYGSKDEK Phybl2 MNNSSQSSRPQTIASPPPPP---PQPQPQRAGLETKRLILLTVGTLWGFAIGGGQQAGLQYLAENAHRLPTTVQGWYFYHKTKNYRMALGGIKRGAKFAGRTGGLCLMYAIEAGLDDIR-DVANSVIAGVTAGTIFSRLTRGSFRYSVLFGAAFGLATGSKENK Picst3 MAD---SIDAESIET--QDLR--------RFHMYPSRLEAFTTAGIIGGFAGGVKRASLRYLTENSHRMPKTVGGWYFYHKKKNYVMIIDGCATGFKQGCKYSAAVGGFGMEWVIDTYVIDFFNTVAAATVYSALYGSLSAVQTRKYILKGSALGLGLGNGPQA Plicr1 MIRVSS-----GEDGKA------------RVYIDSPRYFLLPTAMLVGSMIGGGRSASLRFLAENAHRPPTTKQGWYFYWKTKNYRVMWGALKGGGADAGKLGLTAVGWAAEEGIKKAG--DVRELGAGLATAGVFARLPWKVARRTVAVAVMIGGGLSAKDDV Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------MVENLHRLPQTRANWFFFQKTKNYKVILGGFKGGLRTGAKLGAWTAGFTLKEAF----L-----VPAC--------------------------------PQS Punst1 MSSITTPSSAYDADDDSSPR---------NIHLSIPRFLLLPTAILVGTTLGGSRVASLRFLAENAHRPPTTVRGWYFYNKTKNYRVMMAGLKMAALDAGRLGATAAAWGVEEAVSRAG-EDVSEVAAGTGTAALFSRLPRKVAYRTVALGLLVGCSLSADADS Rhior3 MERSQDPPTPSVQQSYIPPT---PTVQQSRAGLEEKRVILMTIGSLWGFGIGGGRQSGLQYLAENAHRLPTTVQGWYFYHKTKNYKMMLGGMKKGMRYAGKTGGLCLLYSLEAALDDVR-DVLNSVAAGVMTGTIFSKFL---FRFS------------TKPKR Rhoto1 --------------MAEQP-----------IEGAAPLLVLGPSALIFGFTSGSSKLASKQFLAENAHRLPTTVQGWYFYQKTKNYRVLFAGLKGGLKTGARLGLWTGAFGLEQAVDAGLADEVRTTWAGMGMAGAANRLSRASSGRRYFYGLALGALAG----- Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MADASTAPPPNTAELSARPIE--------RVRLPFPRLWIVPGASVLGTLIGGARHASLQYRAENAHRPPRTVGGWYFYHKTKNYKVILGALRQGGRTGPLVGAIAGTYFLEELVERAG--DVKAIAAGLGTSAAVSRLPWYTMKRTMGLGVMGGCMMQKGPDA Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma MST-------TEEPKAAVP--PVPEYVTKRLSIPDARIPLASTALFIGLTLGGIKTAGMRFRAEHAHKLPATKIGWYFYHKSKNYNSIWGGAKEGARMGAKISFWTTAIGIEHMFDAYR-DIFNTVTACVTVSGAFSRFSLPMAARTTKAALAVGLAYGQKERV Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 MDNNKEAQNALTTSFSLPPT---------SYYTSLPRSQLSPAGALGGFMTGGGRQRSYQFLAENAHRMPKTVAGWYYYHKYKNYEIAHFGFKSGFKYAGRFGAISAGFASEALLEALT-SWVNTVGAGLAASIAFSRLTYQYAKYAVLFGLCSSFAVGKDAKS Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 MASTTA------PDASSAPY---------SIHVSVPRLYIVPWAMVVGTLIGGSRAAGLRFLAENAHRPPRTVQGWYFYNKTKNYRMMLAGLRDGGSLAAKLGFIALGWTFEELLDRAG--DVREIGAGVGTAGLVARLPLRTTYQAGVVGLVAGGTMRARDDA Tapde11 MADKSDETDFRNERLSLPPA----------------RLFLYTSSSLLTFVLGGGKKTSYQFLAENAHRLPRTHQGWYFYHKTKNYRVMLGGIQSGFKYAGRTMGWTLLYSTETALDRIR-DAANTVAAAVGTAGIFSGFSRQLTKRTLRMSLLVGLGIGANTKR Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MST-------SIEDPTAGPST--------KISLHIPSLLILPCSAMLGMLIGGGSKARLRFLAENAHRLPTTIQGWYFYTKTRNYRIL---------------------------------------------------------------------------- Trire2 ----------------VFPA-SHP-----RLSIMTPRLLLGSASSMVGFSLGGGQMAQLRFRAEHAHKMPDTTAGWYLYHKSKNYHAMQGGIREGFRMGFKTGIWSLVASLESTVDRYR-DMFSTVIATLTVAGAFSRFSLSTAARTAKYGLVFGLAYG----- Umbra1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 MASLGSASASATANQATQPGSTMPSVAKASLEGVAPVLAISPTAFGLGLISGSGRRAGLVFMAENAHRLPDTVQGWYFYSKTKNYKVLLGAAKGGLKQGARLAVWTTGFSIEKQFGAGR-------WTGTATAAAATRLPRPSAVRVFQLGLLAGASTG----- Walse1 ------------------------------IRINLPRAFPIVCGTLVGFSLGGGRIAGKKFLAENAHRAPKTVQGWYFYNKTKNYRIMQRSLTTGLLDASKIGGIALVW------------------------------------------------------- Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3529.fasta_al_trimmed; alignment length = 69] Allma1 MSKLTRAAWLATFVPALPLWIIVSFGAYSLASIGWSLVTFGDCPEAHQELLQEIQQAKADLRRLKVTVD Ashgo11 --------------------------------------------------------------------- Aspfu1 --------------------------------------------------------------------- Aurde31 MTRANTGIYVALILPVLPWWLLVSFGSYSLWTLGWAMLSFRECPEAYEELTKEVEQAKQDLRRRGVDVD Batde5 MKRALRGIWLIMVIPAIPLWLLVTFGSYSLANLGWALIIFGDCPAAQVSLLKEIQTAKMDLRSHGVSID Botbo1 MTRAQRLAYGLVIIPVIPWWLLVSFGSYSLGTLGLGLLTFGDCPAAHQELLHEISEAKNDLRSRGISVD Botci1 MTRAQQSLYLAVVIPVLPFWVLVSFGAYLLGKLGYGVFTFNDVPKAHAELMEEIELARKDLRTKGVDVD Caeel VSQLVTLVWLLALVNYAPFFAVLFLGIYAVFNVVYGVATFNDCAEAKVELLGEIKEAREELKRKRI-ID Canalb1 MTKATEAIYFALILPYLPWWGLVTFGSYALSTLGWGIVTFKDKEHKYKELKIQIEEAKDFYKTKGIDLD Cangl --------------------------------------------------------------------- Capow ATKLQQAVWTVFIIPALPFVALVAFCAYSLMAIGYRLATFNDCNEASQELQQEVKLARADLSAKGFKF- Catan2 TTKLVRSAWLLAFIPALPLWVIVSFGAYSLASIGWSLITFGDCPEAHAELLKEIAQARDELRRAKITID Cioin --------------------------------------------------------------------- CocheC53 MTRAQQSVYLALIIPYIPFWALISFGAYLLFSLGWGVFTFNDVPEAHAELMQQIAEARKDLSAKGVDVG Coere1 MTRAHRVTWLLGIWPVLPLFFIVALGSYAFINVGYNLLVFRECPEAFHELMQEIQEAKHDLRAKGVDVA Conco1 MTKATELSWALVVWPTFPWVALVSFGAYSLANIGWALITFRDCPEAHQELMVEIQQAKADLRAKKVQID Conpu1 MARAHRVTYIAAILPAVPWWALVSFGAYSLWSMGWGLWTFRDCPEAYTELIQQISEAKNDLRAKGVTVD Copci MARLHRVAYLLCLIPVLPWWLLVSFGAYSLWSLGWGLFTFRDCPEAYNELLSEINDAKNELRAKGVTVD Croqu1 TTRAGRFLYVLLIIPLAPWWFLISLGAYCLGVLGIGLLTVADCSQAYEELIKDIGMAKDDLRQRGIQLD CryneH991 MSKGTRLLYILAILPVLPWWLLVSFGAYSLTSLGLGLVRFHDCPEAYESLLSEISQARDELRNAGVAVD Crypa2 MTRAQQSLYLSLIVPVLPFWALVSLGAYLLARLGWGVLTFNDCPEAYKELMGEIETAKVELRKMGVTVD Debha1 MTKITEAVYFALILPFLPWWTLVTFGAYSLGTLGWGVLTFKDKEDKYKELLNQIDEAKSFYKQKGIDLD Dekbr2 --------------------------------------------------------------------- Dicdi MKRYQKTFWLLLIIPFLPLYAVVCFGSYSLGVIAYNLLIMSDCKEASESLFDEIKEAKESLRAKGMKL- Dmel MTNLQRIPYLSVHIQLLPLLLLVIFGIYSVWTVLYRTLTFNDCPEAAKELQDEIQEARKDLIAKGFRFR Enthi --------------------------------------------------------------------- Falba FLRAHGVAWLASVAKIFPLWLVVTFGAYSGISIGWALFMLEDCPKAYVHTLNDILAARSDLAKMGVNLD Fomme1 --------------------------------------------------------------------- Fusgr1 MTRAQQSLYLALIVPVLPFWALVSFGAYLLFRLGFGILTFNDVPNAHKELTAEIEQAKVELRKLGVTVD Galma1 MTRAHRTAYLLTLLPVLPWWLLVSFGSYSLWSIGLGLFTIRETPEAYNELLGEITLAKNDLRTKGVIVD Ganpr1 MGRRASIAWILVVVPALPLWVLVSLGSYLLWSLGQALFEFRDCPEAFDSLQVDVARAKAELRTRGLPIM Gloin1 MTKATELTYFIFILPVFPWWVLVSFGAYSLGNIGYHVYRFRDCEDAYHELMAEIQIAKDDLKTKGVTI- Hisca1 ----------------------MVIGAYMLFRLGWGVYAFNDVPEEYSSLQEEILEAKNQLRVAKVDVD Klula1 --------------------------------------------------------------------- Lacbi2 MARAHRVLYLLAILPVIPWWLLVSFGSYSLWSLGWGLFTFRDCPEAYTELLREIGEAKNDLRTRGVTVD Lenti61 --------------------------------------------------------------------- Malgl1 --------------------------------------------------------------------- Mellp23 MTRAGRFFYVLLIIPLTPWWFLITLGAYCLAVLGIGLLTVTDCSQAYEELVQDIAMAKSDLRQRGIRLD Mnele --------------------------------------------------------------------- Monbr --------------------------------------------------------------------- Morel2 MTRATETIYLALTLPVLPWWALVTFGAYSLGNIGYHVLTFRDCPEAYDELQVQIGEAQRDLRSKGMNIK Mucci2 MTRATEASYIVLIIPVLPWWALITFGCYCLGNIGNAMYTFRDCPEAYHELMGEISQAKSDLRSKGLQLN Mydma MTKLIQIFYMAALIS--PVLLLALFGFVSVVIIMYRVATFNDCIEAAKELKRECEEAKKDLMSKGIKFD Neucr2 MTRAQQSLYLSLIVPVLPFWALVSFGAWVLFRLGWGMLTFRDTPEAYKELMEEIKLAQADLRAKGVSVD Orpsp11 --------------------------------------------------------------------- Pench1 MTRAVQSLYLSLVIPVLPFYALIVFACYLLARLGVAIFTFNDVPEAHAELQKEIELAKVELRQGKVDVD Phybl2 MTRATEVAYIVLIIPVLPWWGLMTFGSYSLGNLGWHIMTFSDCPDAFNELMHEIQEAKRDLQSKGLVL- Picst3 MTKATEAVYFALILPYLPWWALVTFGSYALATLGWGVFTFKDKEDKYKELLVQIDEAKKFYKSKGLDLD Plicr1 MARAQRAFYLLAILPVVPWWILVSFGAYSLWSMGWGLWTFRDCPEAYTELLLEITEAKNDLRAKGVTVD Polpo FKRYQKSLWLAIIIPVLPLYALVTFGSYSLGSISYNLLIMNDCKEAADSLFD--------VRI------ Pucgr2 --------------------------------------------------------------------- Punst1 --------------------------------------------------------------------- Rhior3 MTRATEIIYFILIVPVLPWWVLMTFGCYCLNNIGYALYTFRDCPEAYHELMSEIQQAKSDLSAKGIQF- Rhoto1 --------------------------------------------------------------------- Rozal11 --------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------- Salro --------------------------------------------------------------------- Schco3 MTRAQRTGYLLAILPLIPWWLLVTFGSYSLWSLGWGLWTFRDCPEAHEELMLEIAQAKTELRAKGVSVD Schpo1 MQRIHKILYRVTLRPYTPYLFILAFGSYLGITLLYNVATTNDKPEAYVDLVKDIKEAQDALRSKGMTIE Sorma MTRAQQSLYLSLIVPVLPFWALVSFGAWVLFRLGWGMLTFHDTPEAYKELMEEIKLAQADLRAKGVSVD Sphar --------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------- Sporo1 --------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------- Tapde11 MTKATQALWTTLIVAVSPLWILVTFGAYLLGTLGWNIFTFKDKEDAYKSLLGEIEEAKTELRAKGVTVD Thetr --------------------------------------------------------------------- Treme1 MSKGKQIAYLLAILPVLPFWLLVTFGSYSLSSLGLGLVRFHDCPEAYESLLMEITQAKNELRDQGVDVD Trire2 MTRAQQSLYFALIVPVLPFWALISFGAFLLFRLGWGVFTFNDVPDAHKELMAEIEMAKVDLSKLGVDVD Umbra1 MTRATEGLYLAFIIPVLPWWALVSFGSYCLGTLGWNVMTFGECPEAYDELMREISEAKGDLRSKGMNIN Ustma22 --------------------------------------------------------------------- Walse1 MTGLKRLAYILSTLPFFPYWALITFGSYSLASIGFGLFTFKDCPEAYNELLSEITQAKDELRARGVDVD Zygro1 --------------------------------------------------------------------- [Cluster3530.fasta_al_trimmed; alignment length = 148] Allma1 LQVLTLMVALSYMIN--GNFTWN-YK-LPSWRRIQFTPEELKQYDG-TDPSK-PIYLAIMGDVFDVTEG-RSYYGPGGGYHFFAGRDAARAYITGCFQ--THLTHDIRGLTPIDDWRQFYGSEKYFKVGRVVHEPID-PNTPIPPPCD Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 IRVLLTLVVLSYYMT-GESVLWG-YR--PWFTRWPLTPDQLALYNG-TDPSL-PIYVAVNGTIFDVSAN-RLVYGPGGSYNFFAGRDATRAFVTGCFQ--EDLTHDLTGVEEVAHWENFFNHKKYFAVGKVVGLEN-L-PKEKRELCK Aurde31 LKFLLFVLVGGKFVT--DSYTWG-YE--GKWTNIKFSEARLAQFDG-TNPAK-PLYLAIDGDVYDVSSS-RHTYGPGGSYHIMAGKDAARAFGTGCFK--EHQTHDTRGMSQLNHWKSFFDHKKYFKVGTVVHKPID-PASPIPAPCN Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 TKMMLWIVGSGWFFT--GSAVWG-IE--SQWLNPRFSEIQLAAFDG-TDPTK-PIYLAIDSDVYDVSAN-RRTYGPGGSYHFMAGKDAARAFVTGCFQ--THQTHDLRGLEKLDHWKKFFKSDKYAKIGWVHHEPID-PKSPIPEPCE Botci1 LRSIVFVLVLSYVVTR-NSYFWG-IK-RPNWTHGEVRGEEFPRYDG-TNPDL-PIYLALNGTIYDVSTG-RRHYGPGGSYHFFAGVDATRAFVTNCFE--EDRTPDLRGVEDLGHWIGFFNSGKYPKIGKVQREKGWETKGEKPKLCE Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 LRILGGILFLSWWFT--STSTWG-YR--GKWLNTDLTISELSLYNG-TDKHL-PIYLAIDGIVFDVSSS-PKVYGPGGPYHELTGKDAARVYVTGCFNKKDEYTYDLRGLDEIQSWQQFFDHDKYWYVGTVQHEPIT-S-DP-PAPCE Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -------------MF--GNLTFN-YK-LPSLNKLKFTPETLKEFDG-TDPTK-PIYLAVLGKVYDVSAG-REHYGPGGGYSFFSGRDAGRAFVTGCFE--THLTPDLRGLSAVDEWREFYNHDQYFYVGTVVHPPID-PNTPIPKHCD Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LRILGGLVLLSYLSTSGESMTWG-YN--PWWTRARLTDSELALYDG-SDPKK-PIYLAINGTIYDVSIS-PTTYGPGGSYHFFAGKDAARAFLTGCFA--EDSVPDLRGVEQLENWHKLFKGKPYRRVGHVKREKDWLEKTPKRGLCE Coere1 IRIMLTLVALSFLIT--ETAFWG-HK--NKWTNWRFTQLELLQYDG-TNPEQ-PILLAIEGDVYDVTLG-SGFYGPGSSYHLFAGRDASRAFGTNCLSRNDHLTHDTRGLSEIRGWHRLFNHQRYVKVGVVSLDPID-PNSPIPPPCD Conco1 ------------------------------------TPEELSKYTG-KDPSL-PIYIAINGDVYDVTEG-RQYYGPGGGYHFFSGKDAARAYVTGCFK--THLTHDLRGFDEIRGWMKFYNHHKYYKVGIVKNPPID-PNSPLPEDCT Conpu1 LKFLFYLTIAGKFFT--GHFLWE-YD--GKWAQLKFSEGFLATFDG-SDLNK-PLYLAIDGDVYDVSSN-RRTYGPGGSYHLMAGIDAARSFGTGCFA--VHRTHDLRGLTEVQHWKDFFNHKSYRKVGRVSHPPID-PLSPIPEHCD Copci LKFLLFALLAGKFVT--GSYTWD-YD--AKWMQLKFSVEYLAKFNG-EDPGK-PIYLSIDGEVYDVTKG--AAYQKGGSYHILAGREGARAFATGCFR--EHMTHDTRGLDELEHWKQFYDHKTYRYVGRLALPPID-PTKPIPEHCD Croqu1 LKYSVLAFLLSRMIM--EHWFWG-YD--GKYVQLNFTLEKLAEYDGVKDPSK-PLLLAIDGNVYNMDKN-KAIYGPGGTYHHFAGKDASRAFVTGCFK--TGLTYDTRGFTKLAHWANFFNSPKYPKVGRVIRPSID-PASPLPQDCD CryneH991 WTFLPILLFSSF-LT--QSYTFN-LS-PYVLPHLRFTPLQLAMFDG-S-PDR-PVYLAIDGIVYDVSAN-RRIYGKGGSYNMMAGRDASRAFTTGCFE--THLTHDTRGLSKLEHWKSFFKSDKYFKVGTILNPPID-TKSPIPPPCR Crypa2 ARVLTFLLFLSYLISGGESFFWS-MKVPPKYLRLELTPEELRAYDG-SDPDK-PIYLAINHTIYDVTAG-SRMYGPGGSYNVFAGVDASRGFVTGCFK--EDQTPDMRGVEELKHWVDFFNSKKYTFVGYVKRPADWLEKEPKRELCP Debha1 LQIIGGLIFLSWWFT--STSTWG-YK--GKWVDPGLTIDELSLYNG-SDSKL-PVYIGINGKVYDVSRS-RGTYGPKGTYGFFSGKDAARAFVTGCFSKEDEFTYDLRGLDPIEGWQTFFSSSKYWYVGIVQHEELA-G-EP-PSPCE Dekbr2 FRIFGGLLILSYWFT--STASWNLLE--GKYTNVDMSLKQLSLYNG-TDSSL-PIYISVNGTIFDVTKS-KHIYGPGGRYHIFAGHDYSRLFVNGCFKKRDQWTFDLRGLDRLEKWSQYFRHPEYWRVGCVDFPSLK-EIEP-PEICD Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LKFIVYCLLVGKFFT--GSFLFD-YE--AKLPALKFSEEGLSKFDG-TDKTK-PIYLAIDGIVYDVTEG-RRTYGPGGSYNFMAGHDAARAFATGCFA--THRTHDIRGLSELEHWKNFFNHKKYFKVGRVLHHPID-PLSPIPEPCK Fusgr1 LRVISFLFVLSYVISGGESYWWG-HKNKPEWMTQKMTLDELSLYDG-RDPDR-PILLAINGTIYDVSPG-RRMYGPGGSYSYFAATDAARGFVTGCFA--EDQTADLRGVEELKHWVDFFNNKKYSKVGYVQRDPDWLEKEKPKKLCG Galma1 LKFIVISLLAGKFFT--GSYIWE-SD--SQWLKVKFSERLLAEYNG-KDG-K-PFYLAIDGDVFDVSKG--KAYQEGGSYHHFVGVDAARAFGTGCFQ--THRTHDTRGMSELTHWKKFYEHKDYIKVGRVNHPPID-PASPIPEHCD Ganpr1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 LQVILTFLIASFFLT--ETWFWG-YE--GKYTNWRFSEAELAKYDG-SDPNL-PIYIAMNGEVFDVTAG-KHYYGKGGGYNFFAGKDASRAYITGCFE--THLTHDLRGLTHLENWAGFYDHHTYYKVGRVVHPPID-PKTPIPPPCN Hisca1 CRVIFLLVLLSYYIT-TDSVLWG-YK--PKFLRWALTPAQLALYNG-TDPSL-PIYVAVDGVIFDVSAN-PRIYGKGGSYNSFAGADATRAYVTGCFS--EDRTPDIRGVELVMHWKEFFNHEKYVQVGRVVGIEK-LMQGPERELCQ Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LKFIVLLLLAGKFIT--GSYTWE-YE--SKWTRLKFSLNLLSEYDG-TTANR-PTYIAIDGDVYDVSKG--AAYQPGGSYHILAGHEGARAFGTGCFK--THRTHDTRGMSELAHWKNFYEHKDYVKVGRVVLPPID-PASPIPEHCD Lenti61 LKFILYATLAGKFFT--GSFLWE-LE----VPDLRFSERMLATFDG-SDPEK-PVYIAIDGDVYDVSSN-RRTYGPGGSYHMMAGKDAARAYGTGCFQ--THLTHDLRGLSEVQHWKKFYDSKKYRKVGRVSHPPID-PASPWPEHCD Malgl1 AYAGFVVLVAGQFIH--GDFLWG-YR--GKWTKWQFTPEELLKYNG-DSGEG-PVYLAIKGDVFDVTPG-RRNYGSGGPYHFFAGRDASRAYVTGCFD--THLTHDLRGLTPLDGWYSFYQHPQYFKVGTVQLPYID-PATPIPPSCD Mellp23 LKYSILMLLLSRMIM--EHWFWG-YE--GKYVQLNYTLKELSNYDGIKDPTK-PILLAINGNVYNMNAN-KAIYGPGGTYHHFAGKDASRAFVTGCFK--SGLTYDTRGFNDLDHWSGFFNSPKYPKVGTVILPKID-PNVPLPKDCD Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ---LCLSVLASYLVT--DTWLWG-YK--GKYTNLRFTQKELLQYDG-SDPTK-KIYLAIKGEVFDVTAG-RPYYSKGGGYGFFSGKDASRAYATGCFQ--THLTHDLRGLTKIDGWASFYNHQKYFKVGTVILDPID-PASPIPEDCR Mucci2 -----------------------------------FTEQELLQYDG-SDPKK-PIYLAIDGDVYDVTLG-GGWYGKGGSYHHFAGKDAARAYVTGCFQ--DHLTHDTRGLSEIAHWKKFYRHHKYHKIGRVLHDPIP-ADAPIPKPCK Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LRVISFLFLLSYLISNGESFFWG-MSHPPNYLQLELTPAELAAFDG-TDESK-PIYLAINGTIYDVSAN-RRTYGPGGSYHVFAGVDASRAYVTGCFA--EDRTPDLRGVEELKHWANFFKSKKYRFVGYVKRDKDWLKKEPVPKLCE Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 IRVIVTLLLLSYYMTSSESVLWG-YR--PWYTRWPLTPSQLSLYNG-TDTNL-PLYVAVNGTIFDVSAN-RMIYGPGGSYNFFAGRDATRAFVTGCFK--EDLTNDLRGVEIVKRWTGFFNHAKYFEAGRVVEDGG-V-HGEPWPLCE Phybl2 LTGLGWAIVGSYLIT--ESWTWG-YR--GKWTNINFSEEQLYRYDG-SNPNL-PIYVAIDGDVYDVTTG-AGWYSVGGSYHHFAGKDAARAYVTGCFK--EHITHDLRGLTTVEHWKKFYNHRSYFRVGRVLHPPID-DSTPIPEPCE Picst3 VRVVGGLLFFSWWFT--STSTWG-YN--GKWINTQLTIDELALYNG-SDMLL-PIYIGVNGYVYDVTAS-RGIYGPKGSYSKLSGKDASRLYVTGCFMNPEEYTYDLRGLKELSEWQQFFEHPKYWLAGYVQRPDPV-G-EP-PAPCE Plicr1 LKFILYLVLAGKFFT--GSFTWE-YE--GKWTQLKFTESLLAQYDG-SAEAK-PLYLAIDGDVYDVSSN-RATYGPGGSYHTMAGVDAARSFATGCFA--THRTHDLRGLSEIDHWKKFFDHKSYHKVGRVVHPPID-PSSPIPEHCD Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 IRYSILILLLSRMIT--EHWLWG-YD--GKWARLSFTLERLALHDGVQDPSK-PLLLAIDARVFDVSAN-PAMYGPGGSYHHFVGKDASRAFVTGCFK--SGLTFDLRGLNDLDYWINFFNSPKYSKVGRLILPDLDASNTPLPVDCD Punst1 LKFFTILLVAGKFFT--GDYLWD-YQ--GKWRSLKITEKQLAQHDG-SDSNK-PLWLAIDGDVYDVSSN-RKTYGPGGSYHGMAGIDAARAFGTGCFK--DHRTHDLRGMLDVEHWKEFFNHKSYPKVGKVVHPPID-PASPIPEASS Rhior3 -----------------------------------FTEKELLKYDG-TDPSL-PIYLAIDGEVFDVTKG-RGWYGKGGSYHHFSGKDAARAYVTGCFQ--DHLTHDLRGLNEVAHWKKFYNHHTYHKIGRVIHDPIP-QDAPLPKPCK Rhoto1 LNWLMIALVLSRAVT--QSWTWG-YE--GKWANPRLSESQLALHDG-SNPSRYPLYIAIDGDVYDVSDGGMRNYGPGGAYSAFAGRDAARAFVTGCFK--THLTHDLRGLSEVENWKSFYKHAKYRYVGRVVHPPIE-PSTPIPELCD Rozal11 -----------------------------------------------------------MGQVYDVSNG-EEYYGKKGSYSIFAGKDASRAFVTGCFSDASHLTHDLRGLSELKNWVKFYESDKYFQVGTLELPEIV-PDSPVPLPC- Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LRGLVYALLAGKFFT--GSFVWG-YD--GKWVHLKFTDRMLAQYDG-SVPGR-PVYLAIDGEVYDVSKG--SAYRPGGSYSFFAGKDAARAFGTGCFK--THLTHDLRGLSEIQHWKDFYDHKDYWRVGRVIHEPID-PNTPIPEHCK Schpo1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Sorma LRVISFLFLLSYLISNGETFFWG-MSHPPNYLQLGLTPAELAAFDG-TDESK-PIYLAINHTIYDVSAN-RRTYGPGGSYHVFAGVDASRAYVTGCFA--EDRTPDMRGVEELSHWVNFFKSKKYRFVGYVKRDKDWLKKEKQPKLCE Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 LLTLGLIIVTSWIVT--DSLTFG-Y----PIPNWRLTTAELAQYDG-TDPSK-PIYLAINGKVYDVSAG-PQYYGKGGGYNFFSGKDAARAYITGCFQ--THLTHDLRGLSELDQWTDFYKHDQYFYVGKVIHDPIP-EDAPIPEDCN Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 VKFLVYVLLGGKFIT--GDFMWG-YR--GKWTNIHFSERTLAQFDG-SDPEK-PLYLAIDGDVFDVSDN-RRVYGPGGSYHIMAGKDAARAFGTGCFQ--THQTHDLRGLTEVNHWKSFFDHKSYHKIGRVQHPPID-PASPIPEHCN Tapde11 VVTAILALLFSKYTH--GNYTFN-YAYPPQYTNARLTEAELATFDG-SHGK--PIYVAVNGSVYDVSAS-PDLYGPGGSYAFFSGKDGARAYITGCFS--TDLTHDLRGVPKLVAWKLFYTHAKYFKVGTVHHPPID-PRIPPPAPCK Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 FPRIIIFILLCRFFT--GSWDAG-LG-DELRPYFRFTPLQLAFYDG-T-PDR-PVYLAIAGEVYDVSKN-RRVYGKGGSYNMMTGRDASRAFVTGCFE--THLTHDVRGLSPLEHWRSFFNHKDYHKIGHILNPPID-PQTPIPPPCR Trire2 LRVITFLFLLSYWISNGESFFWG-QKNKPNYMRVDLTPEELSAYDG-KDPSK-PVYIAINGTIFDVSLG-RHIYGPGGSYNYFAGCDAARAFVTGCFA--EDRTPDMRGVEDLKHWVNFFNSKKYHRVGFVKRDEGWLEREPRRELCA Umbra1 FNILTWGIVSSFLIT--DSWTWG-YR--GKWVNVNLTEQELAKYDG-TNPSL-PVYIAIDGDVFDVTKG-KGWYTPGGSYHFFAGRDAARAYATGCFK--EHLTHDLRGLGEIEHWKTFYNHHNYFKIGTVKHVPID-PKSPIPASCD Ustma22 ---------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 FKWLFYAFALALFLF--DDIFLG-YK--GKYRNLKFTPEELANYDG-THGDE--IYLAVDGLVFDVSAN-KRIYGPGGMYHAATGKDAARAFVTNCFK--DQATYDTRGLDEIKSWQAFFNHKNYNLIGTVENPAID-PSTPIPEDCG Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3536.fasta_al_trimmed; alignment length = 115] Allma1 ------------------------------------------------------------------------------------------------------------------- Ashgo11 VVPCHSIWRQKRSHWHLAEFQAFIKHALIAIETLSIVIFSGVSEASSYFYLTYVHLEEFALDSFDNLLYSIGRFKEITNITIIGFGFKKRRFIEYHQINYIEVEDWYATKKSARN Aspfu1 VVCSHAIYIGSEDEWLIEPFQTFTAHVQAGLRALGLLVFSGLAEGTSYHNLARVITETNATDSYQNVLFSLLRFRSYVKITVVTHEFKRQRFMECHPGAVVGINDPYGVKRVKRG Aurde31 VVAGHAIWHGHEDDWILEPIQTFFKHISKGAELSSLLVFSGETEGASYLRLARATSEQFALDSFQNVLFSIGRFHEVTRITVVSFGAKRARFVELHRFNYVGIDDLYGCKRRKRN Batde5 ------------------------------------------------------------------------------------------------------------------- Botbo1 ------------------------------------------------------------------------------------------------------------------- Botci1 ------------------------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------------------------- Canalb1 ILPCHSIWKSTRDEWHLVDFQAFKQQILTSLQQLSYLIISGISESLSYYLLARVSTEVFARDSFENVIFSICRYYELFKITIVGFEFKRERFVKHHRINYIGNSDWYGLKKIARN Cangl MVPCHSIWNYDPEQWFLAPFQSFIKHGLAGLDTLSTLIFSGVSEAQSYQLLMRITLEEYALDSFDNLLYSLGQFQAVNKMTIVGFGFKQSRYLDLHNINYISIEDYYGRKKQSRN Capow ------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------- CocheC53 IVCCHAIFLPDESNWLLAPFQTFLSHIKAGIDALSILVFSGKTEARSYYHAAYILLEEEATDSFQNLLFSILRFRNVTQIRVITHAFKAKRFLELHRIQIQGIDDPMGTKRQLRG Coere1 LVPGHGVYLGDEANWYLLNEQTFMAHVGKGMEIIALLVFSGHSEAVGYWSAARVVTEDHARDSFENVLFSIARFHELTRVTVVGFEFKRNRFVDLHRFNYVGINDLYGCKRRSRN Conco1 ------------------------------------------------------------------------------------------------------------------- Conpu1 IVPGHSIWTGDEEHWVLADYQAFVEHIRRGTEIAALLIFSGTTEGESYLRLALATTENYALDSFQNLLFSIARFRETTRITVVGYAMKAKRFASLHRFSYVGVEDTYGCKRLSRN Copci VVPCHAIWKGNEDDWILEHYQVFFRHIVEGAKLASLLVFSGTTEAESYLRLARVTTENHALDSYQNLVFSIARFHEFTHITVVGYDFKRARFTDLHRFGYIGVDDLYGCKRRQRN Croqu1 ILPGHAIFVGNPTHWILEPYQTFLNQIKKAASLVSLLIYSG-TEANSYSKIARFTTEEFALDSWTNLLFSVARFKEYTSIKIIGHDYKSKRFVDIHNFEYIGIKDTYGCKRKFRN CryneH991 MVPGHAIWLGEDDDWILEPMQTYVKHIERGVDELSLLVFSGIPEALSYYRLARTATEEYALDSYQNLLFSIARFKEVTKITVVGYGMKRMRFENLHAFHYIGIDSPSGCKRLLRN Crypa2 IVCCHAIWAGDESEWIIESWKTYTEHIKAGLRALSVLIFSGLSEGRSYADLARILVEERALDSYQNILFSLIHFWRSCHLTIVSHAFKRRRLVSAHRVRFVGINDPQGQKRHRRN Debha1 ILPCHSIWTPLRDEWSLVSFQCFKDHILKSLNILATLIISGISEALSYYQLARINTEEFARDSFENVLFLLCRYFELHKITIVGFEFKRQRFLENH-VNYVGNADWYSIKKMKRD Dekbr2 ILPCHSIYIGKEEEWILASFQCLLKHLYTSINLLSLLVISGKSESFSYLQVASILLEKYARDSYENVLFSLCTFRQAAHIKIVGFEFKRERFLNFHNVEYIGIGNEFGCKKEKRD Dicdi ------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------- Falba SLPGH-----------IQP--AIVGHIGRALDQAAVVIFSGRSEGASYWLAARLTTEEFARDSLENLLFSVARFRAFTRVTVVGLQLKRRRFVGQHGFHYIGLDDPYGCRRLAE- Fomme1 ------------------------------------------------------------------------------------------------------------------- Fusgr1 IVCCHGVWLGDENEWLIADFQTFIEHIKAGVAALSWLVFSGISEAAGYKNIAAVLLEERALDSYHNILFSRSLIYSRFHITVVSHGFKKERLIDGHRVNFIGIDDPHGTKRVKRN Galma1 MVPCHSIWKGEEKDWYLEPFQAFYEHIARSAELASLLIFSGTTEAESYLRLARATTENYAMDSYQNLLFSIARFREFTKITVVGYEFKRPRFTELHKFSYIGVDDIYGCKRRQRN Ganpr1 LVAGHGIFNPDPESWWLDPYQTFLEHLKAGVSLAALLMFSGLSEGSSYHLISRVVTEEHSRDSYENLLFGLCRFREVTNVTIISYKHKAFRFTHVHRFNFVGVDDPHGCKRKLRD Gloin1 IVTGHAIYLGNEENWILEDYQAFINHVKKGIELVSLLIFSGRSEAQSYY-----------------------------NISAIT------------------------------- Hisca1 ------------------------------------------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------------------------------------------- Lacbi2 VVPCHAIWQGNEEDWILEPYQAFFKHIEKGVELASLLIFSGTTEAESYMRLARVTTENYALDSYQNLLFAVARFREFTRITVIGYEFKRMRFTQLHKFRYIGVDDKYGCKRLQRN Lenti61 MVPGHAIWKGDEDQWVLEPYQAFFRHIAAGAELASLLVFSGTTEAESYMRLARATTENYALDSYQNLVFSIARFHEYTRITVVGYEMKRRRFTELHQFEYVGIDDTYGCKRRARN Malgl1 IVAGHAIWNGNDSTWFLEDYQTFLKHIETGIQIASLLVFSGTTEAETYMHLARMTTENYALDSFQNLLFSIARFYEFTRITVVSYEFKKDRFTDLHRFTYVGIDDMYGCKRRKRN Mellp23 IL-----------------YH--LSLIRK-----ALLIYSGLSESTSYSNVARVTTEEFALDSWTNLVFSVARFKEFTHITVIGHSFKSKRFQEIHKFEYVSIQDRYGCKRISRN Mnele ------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------- Morel2 ------------------------------------------------------------------------------------------------------------------- Mucci2 IVAGHAIYTGNDKNWILEPYQTFIQHIQKGIDVLSVLIFSGRSEAFSYWNIARMITEEYAKDSHENLLFSICRFSEMTQISVVGFEFKRRRFEDIHQFHYIGIDDLYGCKKMNRN Mydma ------------------------------------------------------------------------------------------------------------------- Neucr2 IVCGHAIWLGDESEWLIEPYKTFIAHIKAGLEELAVLMFSGLSEAQSYYNLARIFLEERALDSYYNILFSLIHYWRVVRITIVSHAFKRNRLVDGHRVRFVGINDPHGVKRRARN Orpsp11 IVAGHGISKTKD--WNIKPFQTFLTHIITGILIASTLIFSGFTEGQSYWYIARATSEEFAKDSYENLIFSICRYHEFTFITLISYPFKHYRFFNLHKFQFVGITDPYGCKKIDRN Pench1 VVCCHAIYAGSEDEWLIEPFQTFIDHIKAGLKALSLLVFSGLSEGQSYLNLARVIAETNATDSYQNLLFSLIKFRVYTRVTVVTHGFKRARFMQCHKVAVIGTNDLYGVKRARRG Phybl2 IVAGHAIYSGQDDYWILESFQTFIQHIDRGLVAASLLIFTGRSEAQSYWEIARVVTEEFARDSQENLLFSLCRFSEITRVTVIGFEFKRKRFLDIHRFEYIGIDDIYGCKKLDRN Picst3 ILPCHAIWKGSAQEWHLVDFQAFKNHITQSVSYLAYLVISGVSESLSYYQLARITTEEFARDSFENVLFLICRFYEVFRITIVGFEFKRARFLDHHKVEYIGNSDWYGIKKMGRN Plicr1 IVPGHSIWKGDDDEWLLEPYQAFFSHISRGAEIASLLVFSGTTEAESYLRLARATTEEHALDSYQNLLFSIARFHEYTSITVVGYEMKRRRFTELHRFRYIGVDDLYGCKRRSRN Polpo ------------------------------------------------------------------------------------------------------------------- Pucgr2 IVPGHAIYIGDPKEWILEPYQAFIKHIQTAANTVALLVYSG-TEAGSYSRLAQATTEDFALDSWTNLIYSVARFKEYTQITVIGHAVKAKRFNELHRFKYIGIDDLYGCKRKKRN Punst1 IVPGHAIWTGSESEWVLEPYQAFFSHIVRGADIVSLLMFSGMTEADSYLRLARVATETFALDSLQNLQFSLARFHEVTKITVVGYEMKRRRFEELHRFEYIGVDDLYGCKRLARN Rhior3 IVAGHAIYTGDDSNWILEPYQTFVEHIKKGIDILAVLIFSGISESFSYWNIARMITEEFAKDSHENLLFSMCRFAEMTKVTVVGFEFKRQRFEDIHQ------------------ Rhoto1 MVPGHAIWQGEDKDWILEPMQTYLKHIAKGAEVAALLIYSGLTEGLSYARLARVTTEDFAMDSMENVLFSIARFKEFTYITVVGYGMKRRRYEDVHAFKYIGIDDMYGCKRRKRN Rozal11 ----------KEDNWFLYHYQEFVEHIRMAVTEHSVLVFSGISEASSYYRISNVFTEDYATDSFENLLFSICRFQQVTRITVIGMYFKEKRFRELHSLNYESPD-----KLIDHN Sacce1 LVPCHSIWKSLPEYWHLAPFQAFIKHGLTAIKLLATVIFSGISEAQSYYFLFSITTEEFSLDSFDNLIYSIYRFEEVNKITIIGFAFKMPRFISCHNITYIGIDDWYATKKRSRN Salro LCPGHGVYIG---NWIIAPFQAFVQHVKRAVELAATLVFSGTSEAQSYLTLARTLLEEYARDSLENLAYTAALIQERAKMQVVGWEFKRARFMQ-HDITYKGLGDPLGNKRRQRN Schco3 IVPGHSIWKGNEDQWVLEPYQALIKHIEIGAKLASLLVFSGTTEAESYLRLARATTEDYALDSYQNLLFSIARFHEYTKITVVGYEMKRARFTELHKFKYIGVDDTYGCKRRQRN Schpo1 IVAGHAVWLGDDSEWILEPYQVFAQHVRSGLDLLSLLVFSGSSEAQSYYSLSRRTTEEFARDSLENVLFSVARFYEVTKITVVSFDFKRDRFLNLHKFHFVGIDDPYACKRMERN Sorma IVCGHAIWLDDESEWLIEPYKTFIAHIKAGVEELAVLMFSGLSEAQSYYNLARIHLEERALDSYYNILFSLIHYWRVVRITIVSHTFKRNRLVDGHRVRFVGINDPHGVKRRARN Sphar ------------------------------------------------------------------------------------------------------------------- Spipu1 ------------------------------------------------------------------------------------------------------------------- Sporo1 ------------------------------------------------------------------------------------------------------------------- Stehi1 MVPGHGIWEGDERRWVLKEYQVLVEHIRKGAHIAALLVFSGTSEAESYHRLARATTEPFALDSYQNLLFSIARFKEYTKITVVGYEFKRRRFEQLHEFEYVGLGDPYGCKRLQRN Tapde11 MVAGHAVWLGNDSDWFLESRQTLAEHVRYGAQLASLLIFSGRTESQSYAELLHVTTEEFARDSFENLLFSIARFYEIVAITVIGFQFKKQRFRDVHKFTYHGIDDLYGCKKKSRN Thetr VVAGHTVFAGSPDGWLLQPYQAILDHIRTGVAIAAVLVFTGRSEAESYLHAARTVTENAARDSLENLLFSICRFREVTRITVVSFEFKRNRFTNVHCFSFVG-NDPFGCKKQARN Treme1 IVPGHAIWIGNDDEWILQDMQTFLKHLKEGVERMSLLVFSGLSESLSYYLLARTTTEEYALDSYQNLLFSISRFHEITRITVVGYGMKSFRFVNLHNFDYVGIDDPTGCKKINRN Trire2 IVCCHGVWTGSEDEWLIADFQTFIEHIKAGLRCLAMLAFS------GYANIAKVLIEDRALDSYHNVLFSLTLFYTRFHLTVVSHAFKEPRLVNGHRTAFVGIDDPHGRKRRRRN Umbra1 MVPGHAIYHGNDEGWTLEEFQVFMNHIKKSIELLSLLVMSGLSEAQSYWQIARIATEEHARDSMENLLFSICRFYELTKITVIGFEFKKERFINIHRFHYIGIDDVYGCKKLDRN Ustma22 IVTGHAIWAGNDENWVLEEYQTFYKHIEKGMQLTALLVFSGQTEAESYYSLARMTTENYALDSFENLLFSIARFREYTRITVVGYAFKKARFEDLHTFQYVGIDDMYGCKRIERN Walse1 ------------------------------------------------------------------------------------------------------------------- Zygro1 IVPCHSIWNPNPEHWYLKPFQAFIKHGLQAIITLSFLVFSGLSESQSYYLLMRVTTEEYALDSFDNLIYSIYRFKQMNEITIVGFGFKKKRFLELHRMNYISIDDWFATKKQSRN [Cluster3539.fasta_al_trimmed; alignment length = 58] Allma1 GRAWEASELRQKSFEDLHKLWYVLLKERNLLATQKLEAKRCKKSMARIKGVLTERQLT Ashgo11 ---------------------------------------------------------- Aspfu1 GRSWSIQELREKSWEDLHCLWWVCVKERNRIATSNLERQRIRITQNGIKHVLRERWYA Aurde31 GRAWTAEELRRKSFRDLHTLWYAVARERNLLASQRDEARRCRDTQARIKLVLSERRHA Batde5 GRAWLAAELRNKSFDDLHSLWWVCCKEKNKLYSQQMEARRVKLTMSRLKLVIWERREA Botbo1 GRSWTAAELRRKSFKDLHTLWYVLLRERNLLATQKHEAMRVSKSMARIKGVLNERRLA Botci1 GRPWSAEELRGKSWEDLHSLWWICCKERNRIATESYERQRVRRTQRAIKQVLTERYYS Caeel ---------------------------------------------------------- Canalb1 ---------------------------------------------------------- Cangl ---------------------------------------------------------- Capow ---------------------------------------------------------- Catan2 GRSWEASELRKKSFDDLHKLWYVLLKERNLLATQQQEAKRVKKSMARIKQVLSERQGA Cioin ---------------------------------------------------------- CocheC53 GRAWTVGELRSRDWDALHQLWWVCVKERNRLATEKIERKRVQETMKAILDTLAERHQA Coere1 GRAWSASELRQKSWEDLQKLWYIVLKERNLLASQKVECRRCQKTMARIKTVLNERQIA Conco1 GRAWRAAELRLKSFDDLHKLWYLNLKERNLLSTQKAEAKRCKKNMARILFVLNERRIQ Conpu1 ---------------------------------------------------------- Copci GRSSRSADWRTGKVPDLHTLWYVTLRERNLLATQREEARRCRKTMARIKAVMNERRLA Croqu1 ---------------------------------------------------------- CryneH991 GRAWTAAELRQKSFKELHTLWYVLLRERNVLATQREERRRCRKSMARIKYVLNERRLG Crypa2 GRAWNVEELRRKSWDDLHRLWWVCCKERNRISTGNAERKKVRKTQNAIKHALTERFYA Debha1 ---------------------------------------------------------- Dekbr2 ---------------------------------------------------------- Dicdi GRSWAASDLRGKSFNDLHELWFELLKERNKLLTEKEITKNVRKSMAAIKVVLGERDQL Dmel ---------------------------------------------------------- Enthi ---------------------------------------------------------- Falba GRSWTASELRTHSYEDLHKLWFVLLKERNMLLT-----QRVRKSMARLKHVLGERSAA Fomme1 GRSWNAVELRRKSFKDLHTLWYIVLRERNLIATQRQEAKRCRKTMARIKQVLNERRLA Fusgr1 GRAWTVEELRKKSWEDLHALWWVCCKERNMLSTSRAELLRVMKTQRAIKHVLTERYYT Galma1 GRAWEASELRNKSFKDLHTLWYISLREKNLLATQKEEARRCRKTMARIKMVLNERRLA Ganpr1 GRFWTHSELRRKSFDDLHKLWFVCLKEKNLLYSQMEEARRVKVTMRNIKFVLGERKKV Gloin1 -RAWTASELRRKSFEDLHKLWYVLLKERNLLGTMWLEAKRCQKSMARIKHVLSERRVA Hisca1 GRAWSIQELRQKSWDDLHKLYWLCVKERNRIATARYERQRVRGTQQSIKQVLRERWYA Klula1 ---------------------------------------------------------- Lacbi2 GRAWKASELRLKSFKDLHTLWYVSLREKNLLATQKEEVRRCLKTMGRIKAVINERRRA Lenti61 GRAWTAAELRRKSFKDLHTLWYVVLRERNLLATQQAEGRRCRKTMARIKYVINERRLA Malgl1 SRAWLAPELRRKSSADLHTLWYVLLLERNKLATSWEELKRVRKSMARIKYVLNERRLA Mellp23 ---------------------------------------------------------- Mnele ---------------------------------------------------------- Monbr GRRWLARDLRLKSDPDLHKLWYVLLIEKNKLMTAKYECRRVRKSMAALKTVTEERQNA Morel2 GRAWRASELRVKSFDDLHKLWYVLLKERNVLAAQKEEARRCQKSMARIKFVLNERRLA Mucci2 GRAWKAQELRQKSFDDLHKLWYVLLKERNVLATQREEATRCQKSMARIKFVLNERQRE Mydma GRKWKKSELRIRSNSDLHKFWYVLLKEKNMLLTMRQEAKRVNKSMLAVKSVIKERNDA Neucr2 GRAWTVSELRKKSWDDLHRLWWVCVKERNRIATANWERTKVKQTMRGIKHVLTERFYA Orpsp11 ---------------------------------------------------------- Pench1 GRAWAIQELRERDWQDLHGLWHVCVRERNRIATSDLERERIRSTMRNIKHVLRERWYA Phybl2 GRSWKADELRAKSFDDLHKLWYVLLKERNVLATQREQAKRCQKSMARIKFVLNERQIA Picst3 ---------------------------------------------------------- Plicr1 GRAWTAGDIRRKSFQDLHTLWYVLLRERNLLATQAEELRRVRKSMARIKFVLNERRLA Polpo GKSWEARDLRGKSFEDLHKLWFVLLKERNKVMTEQELAKNIRKSMAAIKVVLGERDRL Pucgr2 ---------------------------------------------------------- Punst1 GRSWTAKELRLKSFQDLHTLWYILLRERNLLATQKEECRRCRKSMARIKYVLNERRLA Rhior3 -QIWTG----------------------NI---------------------------- Rhoto1 GRAWKTEELRIKSFEDLHKLWYILLRERNVLLTQKEEARRCRKSMARIKGVLAERRNA Rozal11 ---------------------------------------------------------- Sacce1 ---------------------------------------------------------- Salro GRRWKTRELRVKSNEDLHKLWYILLIERNKLLTVKLEARRVKQAMDSIQLVLRERVSA Schco3 ---------------------------------------------------------- Schpo1 GRAWAAEELRWKSFNDLHGLWYNCLREKNLLFTQRAEMKRVNKTMAAIKFVLWERQRA Sorma GRAWTVSELRKKSWDDLHKLWWVCVKERNRIATANWERTKVKQTMRGIKHVLTERFYA Sphar ---------------------------------------------------------- Spipu1 GRAWLAAELRKKSFEDLHQLWWVCIKEQNKLYSQKEEARRVKLTMNRIKQVVWERRTQ Sporo1 ---------------------------------------------------------- Stehi1 GRAWETAELRRKSFRDLHTLWYVLLRERNLLATQRHELSRCRKSMARIKGVLQERRLA Tapde11 GRSWTAEELRKKSFDDLHSLWIICLKERNILSTQRHERRRVRRTMAGIKFVLNERFLA Thetr GRAWSASELRLKSLEELHALWFVLLRERNKLNSEREAARSTRKSMARIKRILGERSQA Treme1 GRSWTANELRQMSFADLHTLWYILLRERNLLATQREEFRRCRKSMARIKYVLNERRLG Trire2 GRAWTVEELRRKSWEDLHALWWKCCKERNMLATAREELLRVTKTMRAIKHTLTERFYT Umbra1 GRSWKASELRLKSFDDLHKLWYVLLKERNVLATQREEARRCKKSMARIKFVLNERQKA Ustma22 SRSWLASELRLKSSKDLHILWYVLLMERNRLATAWEELNRVRKSMARIKFVLNERRLA Walse1 SRSWRASELRLKSFEDLHTLWFILLRERNLLSTQLEESRRVRKSMSRIKFVLSERHHS Zygro1 ---------------------------------------------------------- [Cluster3540.fasta_al_trimmed; alignment length = 66] Allma1 PENRTWFEARDQHLREQWVEQMTTVIIKEKLQRCTRQEGVNAPENCHHLVEAYMDRLRRGGFKSWR Ashgo11 ------------------------------------------------------------------ Aspfu1 PESAAFHNARDAIIREQWVRSMMSRLVGEELGKCYAREGVNHLEKCGKLREKYFELLKERKVKGYL Aurde31 ------LDARDHHIREQWVKAMEVRLVREELVKCQRGEGANAPVHCKELSERYLSMLGDAKIKGWR Batde5 ------IKSRDEYYKEQLVTGQEIRILRDKLRWCYIREGVNHLQNCRHLSTQLMEVMR-------- Botbo1 ------IAAREEHIRESWVRAMEMRIVREEMAKCHASEGVNHYANCKELAQKYTEMLKTNKVTGWR Botci1 PESAAFKQAQDAIIREQWVKSMMARLVREELGKCYYKEGVNHLEKCGALRDRYFELLKESKIKGYL Caeel ------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------ Cangl ------------------------------------------------------------------ Capow ------AEGKERFVRERLILTEVTAIFREQTSACYRREGVNHLENCKDVVEAYQRHLDRRRITELR Catan2 PENRKWLEARDQHLRQEWVEVMKTKIIREKLVRCYKREGVNHVDNCTHLVEAYVDRLKRGGIKSWR Cioin ------------------------------------------------------------------ CocheC53 PESELFKAAQDAIIREQWVRSMMARLVREEMGKCYRREGVNHLEKCGHLRERYFELLKDAKVKGYL Coere1 ---------RDRMVREKWVKIMKLRIVRDKLEECYHSQSVNHMQNCRDLVERYLKDLPEARISGRP Conco1 ------MEARTQRIREDWVKVYEARIIRNALFKCYRTEGVNHYQHCRHLAEAYLDRYQKDRV---- Conpu1 ------------------------------------------------------------------ Copci ------LTKREEFLRESWVRAMEARLVQEELGKCHQGEGVNHYENCKWLADKYLTMLRENRVKGYK Croqu1 -------EAREAKIREDWIRVMEMRITREKLAECYRTEGVNSYEQCAHLAQTVLDQIPEGRVKGFR CryneH991 ------IKSREEHVRESWIKAMEARIVRDELQKCYRGEGVNQLQNCKALAEKYAAMIRDNKVKGYK Crypa2 PESAAFKQAQDAVIREQWVQVMMGRLVREELSKCYYREGVNHLEKCGPLREKYLQLLEKAKVRGYL Debha1 ------------------------------------------------------------------ Dekbr2 PNSGRPKAARESMLKEQFVRVEMLKIVRKALETCFQVNGPNNYEECRNLADKYLDMLPDHRAQGYL Dicdi ------------------------------------------------------------------ Dmel ------------------------------------------------------------------ Enthi ------------------------------------------------------------------ Falba ------------------------------------------------------------------ Fomme1 ------VRAREEHIRESWVRTMEVKIVRDELTKCQRIEGVNHYENCKPWTEKYLKMLRENRVKGYK Fusgr1 PESEQFKAAEDALIREQWVGAMMTRLVGEELNKCYVREGVNHLENCGHLRERYLQLLKSNKIKGTK Galma1 ------LQEREDNIRESWVKAMETRLVREELAKCHQAEGVNHYENCKWLSEMYLHLLRTQRVKGYK Ganpr1 ------LSARDQYFREQMVRMQEISILRDKLKWCYRREGHNAKESCRELALAYVEFLKEDWIAPFK Gloin1 PVHKTFLDAREQKIREDWIKVMELRLIRDQLKKCYKTESVNHYQNCKELAEKYLSLLKDSKVKGWK Hisca1 PESAAFHNARDAIIREQWVRSMMARLVGEELGKCYRREGVNHLEKCGMLRDRYFELLKEAKIKGYM Klula1 ------------------------------------------------------------------ Lacbi2 ------LQERENNLRESWVRAMETRLVQNELGKCQRGEGVNHYENCKWLADKYIQMLRENRVQGYK Lenti61 ------LAEREHIIRESWVRNMEAKLVRDQLDRCYQTEGVNHLESCKDIRERYIDMLRDNRVKGYK Malgl1 ------------------------------------------------------------------ Mellp23 -------EAREAKIREDWIRVMEMRINREKLSECYRTEGVNSYEQCAHLAQKVLDQIPDGRIKGFR Mnele ------------------------------------------------------------------ Monbr ------------------------------------------------------------------ Morel2 PTQRKFLRSRALAVRESWINAMEGRIIQEELKKCYRAEGVNHYQNCRHLVDLYMNALKEKRVEGWR Mucci2 ---------RNQKIRDDWVKAMEARIIKEKLDECYRTEGVNHYKSCRDLADMYLATIKTHRVEGFR Mydma ------------------------------------------------------------------ Neucr2 PESAAFKQAQDAIIREQWVRVMMGRLVREELSKCYYREGVNHLEKCGHLRERYLQLLSENRVQGYL Orpsp11 ------------------------------------------------------------------ Pench1 PESAAFHNARDAIIREQWVRSMMARLVGEELGKCYAREGVNHLEKCGVFREKYFELLKESKIKGYL Phybl2 ---------RNQKIRDDWVKAMEARIIKEKLDECYRTEGVNHYQNCRELANMYFTALKENKVEGFR Picst3 ------------------------------------------------------------------ Plicr1 ------LKARDDHVRESWVKAMEARLVREELSKCRAYEGVNSYENCRWLAEKYTTMLKENQIQGYK Polpo ------------------------------------------------------------------ Pucgr2 -------EARDKKIRDDWIRVMEMRINQEKLAECYRTEGVNSYEQCAHLAQTVISQIPEGRIRGFR Punst1 ------------------------------------------------------------------ Rhior3 PEHRQFYAARNQKIRDDWVKAMEARLIKEKLDECYRTEGVNH---CKF------------------ Rhoto1 ------LQSRDEKIRQDWIGVMETRIVREELAKCWRTEGVNAYEQCHHLTERYLDMLRTNRLEGYT Rozal11 ------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------ Salro PEDK--FKARGQEAAQRLIGVEKLKILRERVRKCHREEGVNHFENCAEPVDAYLKALEANAL---- Schco3 ------YEERDNIIREQWVKAMEARIVREELQKCHRAEGVNQQENCKWLAEKYLEKLEGSRIKGYK Schpo1 ------------------------------------------------------------------ Sorma PESAAFKQAQDAIIREQWVRVMMGRLVREELSKCYYREGVNHLEKCGHLRERYLQLLSENRVQGYL Sphar ------AEERKLKAVNDQVHNRYVKILRKEVTECYRREGVNHEEKCKDLVEAYWQAYKGRQPKGPP Spipu1 ------VKSRDEFFREQMVRIQEVTVLRDKMRWCYRREGVNHLQNCRHLSQQYLDLMKEGWIKPFK Sporo1 -------AKREEKIRQSWIGVMEAKLVREELQKCWRTEGVNHYEVCHPLTEKYLDLLRTNRVR--- Stehi1 ------VSSRDEHIRETWVRAMETRIVKDMLQTCQRSESVNHYENCRELADKYISMLRENKIQGYK Tapde11 ------------------------------------------------------------------ Thetr ------------------------------------------------------------------ Treme1 ------IQERELHIRESWVKAMEARLVRTELQKCYRGEGVNHLKNCKELAEKYAAMIRDNKVTGYK Trire2 PESELFKAAEDAIIREQWVGAMMTRLVGEELGKCYVREGVNHLENCGHLREKYLQLLGQNKVKGTK Umbra1 PEHRQFYAAREQKIRDDWVKAMEARIIRDQLSKCYKTEGVNHYQNCRELADMYLKAVKENKVEGFR Ustma22 ------LAQREEKIRESWVRTMEARIVREELQKCHKAEGVNHYQVCSDLAKKYHSLLADAKVKGFR Walse1 ------KDAQDNHIRESWVSAMELRLVKQELQKCHQYEGVNHYANCQQLSNRYVDMLKDHRVKGYK Zygro1 ------------------------------------------------------------------ [Cluster3543.fasta_al_trimmed; alignment length = 74] Allma1 -PAFDQYDFDHDATFQSGLAAILKAKQFYYHK--------TFAEIVKLVSEGK--PVPGIRIPDVLNTPRKPWE Ashgo11 -------------------------------------------------------------------------- Aspfu1 FRKLNSYPFTTDVEFAKGLSIILQAKCFYFSRLDFKRYKTSFARIVELITTGQ--QIPGIQIPDTVLTRRKPWE Aurde31 YRLFEQYPFSADEQFREGLEVVIQAQLFFFARVTRAGYRRSFAEIVELVKAGQTHLVPNNKVPEGLNTRAKPWE Batde5 FEQFLSYDFEKDERFTQGLQQAMQAKVFYFSKLDYAAYKKTFQEISERVARGE--PIPGIRIPDTVHELKKPWE Botbo1 YEGFNSYDFASDETFQQGLSSIIRAKAFYFSKISWDGYLASFSAIAELISTGNLHLVPNNKIPDGLNSPRKPWE Botci1 YKDLASYSWDTDNEFQGGLSAILRAQCFYLSRINFDGYKASFAEIVALITTGA--TIPGIRIPDTVLTRRKPWE Caeel -------------------------------------------------------------------------- Canalb1 YIEYLNYDWDSFQEFQDGLQEIMQAKSFFFCNINLDDFEDNYQELVGLLMSGK--PIPGIKIPDTVLTRTKPWE Cangl -------------------------------------------------------------------------- Capow -------------------------------------------------------------------------- Catan2 -PAFDDYDFASDAVFQAGLESILKAKRFYYAR------STSFAEIVQMVAEGK--PIPGVRIPDKVADRLKPWE Cioin -------------------------------------------------------------------------- CocheC53 YEALERYNWDDDVEFQAGLQAIIRARCFYYARIDFDAYKASFAHIVELITSGK--PVPGIKIPPTVLERKKPWE Coere1 FKAFEAYDFDNDKTFQAGLSNIPKAKAFYYSKIDLSKYEGSFAEVVGMIMRGE--EIPGARIPDELNTPPKPWE Conco1 -MNFEDYNFDEDENFKKGLSSILKAKQFYFEK--------SLKEITDLISSGQ--PIPGIKIPLKINERKKPWE Conpu1 VQHFLAYPFSTDQVYQQGLSAILRAELFYFNRLTLEDIQATFAELKALIEEGKTDGIPNNKIPDVIHERKKPWE Copci LEQYAAYRFDADDTYQQGLASILRTRVFYFNKITMEDARETFAELKELIETGKVDQIPNNKIPEKFSERKKPWE Croqu1 -------------------------------------------------------------------------- CryneH991 FEEFESYPFNNDPEFRAGLPTVIRAQWFYFTRLPWESYARSFEMLVRLIKEGKADRVETTPVPDELNERPKPWE Crypa2 LRSFHDYRWDLDKDFLGGLVLALHSRIFYFARVAYATYRAKFAAIIQAVQSGE--PVEGIIIPDVVARPRKPWE Debha1 YKDYLNYDWDSFSEFQDGLQEILQAKCFFYCSLNLDDYNENYQKLVELIVSGK--PVPGIKIPDTVVPRLKPWE Dekbr2 YQQFHHYDFDGNNEYKEGLVAVLQTKVFFFCKLDLDDYRRNYEQLVDMIVNNK--PIPGIKIPDTVLDRSKPWE Dicdi -------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------- Falba -------------------------------------------------------------------------- Fomme1 LEEFAAYPFHSDQAFQDGLTSILRAKAFYFSSISWDDVRNSFTEITALIESDRTHLIPNNEISGGVNDRRKPWE Fusgr1 FTAFDTYPWTKDKNFMSGLCAILHARIFYYAQIDFGSYKSGFAEMIKLIQEGK--PVPGIRIPNTIVRPRKPWE Galma1 LKTYASYPFDSDETYQQGLASILRTRVFYFNKITAEEARDTFSELKELIETGNVDKIPNNKIPEGLNVRKKPWE Ganpr1 FSKFTTYDFDGDPVFSSGLGAVVGSKLFYFGKIPPARYQSSFQDLVQMLADGK--PIPGIKIPDTLAERKKPWE Gloin1 FKAFESYDFENDINFQSGLPSILKAKYFYYSKFDYDDYLATFHQLVEMISKEQ--PIPGIKIPNELNKRPKPWE Hisca1 -------------------------------------------------------------------------- Klula1 -------------------------------------------------------------------------- Lacbi2 LDQYGAYPFAEDETYQQGLASILRTRVFYFNRISMDEARETFAELKELIESGKMDQIPNNKISEALNDKKKPWE Lenti61 LSRFLAHDFANDDEYQQGVAGILRSEVFYFNRITVEEARSTFAQLKMLIEQGRTDEIPNNKIPNVLSSRKKPWE Malgl1 ------------------------------ST----GQTPSFHKIVELIATGQESNIPGIRIPLQINSPKKPWE Mellp23 -------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------- Morel2 FQKFENYDFEADANFQAGLKSIIKAKYFYYSRFDYNQYQASFQEICELIASGK--PIPGIRIPNNLAEKLKPWE Mucci2 FKQFDQYDFDKDSQFQSGVASLLRAKLFYYTKFDADAYKTTFQELVDMIEKGI--EIPGIKIPNVLNERPKPWE Mydma -------------------------------------------------------------------------- Neucr2 ---------------------MLQARVWWYKSIDRSAYENRFNAIIELITNGT--PVPGIKIPNTVVRPQKPWE Orpsp11 FNAFTNYPFDEDPIFNKGKAVIINAKVFYLKKLESSDTTK---------------------------------- Pench1 FERLQSYSFVSDPEFANGLSIILQAKCFFFSRIDFAAFKSSFAHIVELITTGQ--PIPGIQIPDTVLSRRKPWE Phybl2 FEAFSKYDFDNDTRFQSGVSSLMRAQWFYYTKFDLDAFRETFQELVEMIETGK--EIPGIKIPNTLNERRKPWE Picst3 YKEFLNYDWESFSEFQTGLQEILQAKSFFFCSLNLDDFQQNYQHLVELIVSGK--PVPGIKIPDTVLSRVKPWE Plicr1 RRQFTAYPFAEDEAFQQGLSSILRSQIFYFNRITLESLAESFAELKDMIESGNTDQIPNNRIPDVLNDRKKPWE Polpo -------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------- Punst1 LELYSKHSFSSDQAYQQGVASVIKSRVFFFNRLTVEEVALSFAELKALIEQGELDQIPNNRIPEGIHMRKKPWE Rhior3 FEAFEKYDFDNDAQFQSGIASLLKAKLFYYSKIQYDEYIKTFQEIVDMIEKGI--EIPGIKIPNIINDRPKPWE Rhoto1 LPTTR-----TDPTFLQGLELILRAEAFYLSS--------TFAQLAALIATGA--PIPGIKIPDKLAERRKPWE Rozal11 -------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------- Salro -------------------------------------------------------------------------- Schco3 LEQYGAYDFAKDDVYLQGLASIIRTRVFYFNN--------TFVELQALIEAGRVDEIPNNRIPDKLNDRKKPWE Schpo1 -------------------------------------------------------------------------- Sorma FKKFDAYPWIKDRPFLQGLVAMLQARVWWYKSIDRSAYENRFNAIIELVTNGT--PIPGIKIPDTVVRPQKPWE Sphar -------------------------------------------------------------------------- Spipu1 FREFTAYNWDKDQRFQQGLQSILKAKCFYYSKINYLQYLKSFQELCEMVARGE--EVPGIRIPNKINERRKPWE Sporo1 -------------------------------------------------------------------------- Stehi1 VRLYADYDFDTDPLYQEGLSSILRSRIFYFARISAEDAARSFDELRELILHGKTDQIPNNKIPDKLSDPKKPWE Tapde11 ----------------------------------------SFAEIVDLISSGK--PIPGIKIPDKIADRTKPWE Thetr -------------------------------------------------------------------------- Treme1 FDEFEAYPFSDDPDFKAGLPTVVRAQWFYFTRIPWEAYAQSFAMLCRLISEGRAGEVAQAQVVDAINSQPHHQS Trire2 FRAFDSYPWTKDAAFLSGLRAILHARIFYYAQIDFAAYHAAFAEMIKLLQEGK--PIPGIRIPNTIERPRKPWE Umbra1 FQAFDHYDFDKDDRFQAGLPSLLRARWFYYTKFDYTEYQQTFQEIVERIEKGE--EIPGIKIPNKLNERPKPWE Ustma22 YTALAQFD-ESDPEFQAGIQTIIRAKVFFWSQVDYADYTASFDAIVELITTGKTDQIPGIRIPLKINQPLKPWE Walse1 -------------------------------------------------------------------------- Zygro1 -------------------------------------------------------------------------- [Cluster3556.fasta_al_trimmed; alignment length = 325] Allma1 APVLASAPGKAILFGEHAVVYGKTAIATAVD-LRSYVLYPA-PSAHGVVTIVFPDDLDPDRRAALAVLHVLLELLVLRS-EIPVGSGLGSSASLSVALAVAMLGVVGCGGEVAKLTTVNAWAFASEKVIHGNPSGVDNTVVTYGGSLAY--TKG----MVPLFKFLLTNTLVEKNTKTQVDKVRRRRDLL-PTVINP-VLDAMHHLATTAQSLLTA-----------TADLSPLIHVNQTLLAA-LDASHPAIDSVVALTAAHGL-PSKLTGAGGGGCVMTYVPVDTVMDNLREAGFDTFKGMGVALVKDWDAWVAKEVRRRR-- Ashgo11 LPFITSAPGKVIIFGEHSAVYNKPAIAASVSSLRTYLVEA--DAESDAVRMEFPDELDAEVLAALCFLYIYTCLFTVKS-TLPIGAGLGSSASIAVCLALAMGGHV---ES-GAQDFVNRWALVGEQCIHGTPSGIDNAVATYGDAVLF--QRQGSTKFDHLMPMILTNTKVPKSTKVLVANVGKLVEQE-PLITAP-ILNTMAQVVTQAHELLPLQGD--DTV---YTRLLQLVRINHGLLVA-LGVSHPSLEHVRALCDTLGIGATKLTGAGGGGCALTLLKVEQFRKTLLDKGYESFTGVGCCLTLFQE--LAEAL---IDW Aspfu1 PAFMVSAPGKVIVYGEHAVVHGKAAMAAAIS-LRSYLVTTL-SKSQRTITMNFRDSLDPELVSASAFLYLFLSLYTLRS-TIPIGAGLGSSASVCVCLSAALLRTLAGPDQPPDIERINRWAFVGEMCTHGNPSGVDNTVSAGGKAVVF--RREKPPTVTPLLPLLLVDTRQSRSTAVEVAKVGKLKDEY-PVVTDS-ILEAIDQVTLAAQQKIQENGI--SYR--TLEDLGTLIRINHGFLVS-LGVSHPRLERIRELVDYADIGWTKLTGAGGGGCAITLLRVRELEEKLSAEGFVKYEGDGIGVEIDQQKFIERLVEGWKFW Aurde31 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 RSYLVSAPGKAIIFGEHAVVYGKSAIAASI-DLRTTAIRPI---SD-FITLSLPDLLPLKIQSASAFLTLYTQILDVTS-ALPIGAGLGSSASFSVCVASLLLGTIQMP---DQLNLINNWAFISEKVIHGNPSGVDNSLCTFGGARVY--TKL----IQELLEFILTNTTVPKSTKHEVEKVRLRREKF-PYIVNS-LLDSIQAISDCCTSACLKQNT---ITLDLIEQFEVLVDMNQSILVG-LGVSHPKLELIRLITSQHGH-RSKLTGAGGGGCALTIIRISTLCDALECEGFQCFRCKGV------QAC----------- Botbo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 PPFMVSAPGKVIVFGEHAVVHGKPAIAAAIS-LRSYLVTSL-SKSKRTISLRFPDSLDPELVSASSFLYIFLSLYTLRS-TIPIGAGLGSSASISVCLSSALLRTLSGPDQPSNLERINRWAFVGEMCIHGNPSGVDNTVSTQGKAVIY--QKS--PTVKPLLPLLLVDTQQAKSTAHEVAKVDLLKQKH-PAIVDS-ILNAIDMVGQSAAVMISDDSE--DLK--CVEDLGKLMTVNHGLLVS-LGVSHPRLERIRELVDHEGIGWTKLTGAGGGGCSITLLKMTRLEETLETEGYKKFECDGVGVEIDQEKFVEELVEAWKFW Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 LPFIVGAPGKVIIFGEHAAVYGKPAIAAALS-LRCYLVSP--SSDSNTIRLQFPDELVPEIVACFCFLYLLMNLFIVRS-TLPIGAGLGSSASTSVCLSSALAGWINKPDKLDTLEFIDKWSLIGEKCFHGNPSGIDNAVATFGGAVMF--QRTQPSIRTNMIKLLLTNTKVPKSTADLVAGVGRLNAEF-NSISTS-ILTAIEHLSQEAYKVMMNGRE--ETN-----VLRKLVNINHGLLVA-LGVSHPALETVKIIGDKHRIGATKLTGAGGGGCAITLVNIHNAIKEFEDSGYESFEGKGVGIKFSESQFIEDSLKEWKFW Cangl LPFLVSAPGKVILFGEHSAVYNEPAVAASVSSLRTYLVSPAGSNAEDSIELSFPDNLNEELVAAFCFLYLFCTLFSVKS-TLPIGAGLGSSAAISVSLAMAMLGKL---G--ESKALINEWAFIGEKCIHGTPSGIDNAVATYGNAVLF--KRSGTTDFEFLIPMVLTYTRIPRSTKVLVSSVRDLSNKY-PKVIQDHVIKAMGELALESVDILNSGGN--DSN---YERLLDLVNINHGLLVA-IGVSHPGLEIIRNLSITNSIGATKLTGAGGGGCAFTVLNVDKFKEELSKKGYLSFTGAGSCMNLVAPLFLDKTL---LFW Capow MQLVVSAPGKVILHGEHAVVYGKTALATALD-MRTSVVTEG-ATQGTESRVALADGVDREALALKTFLQILVAVASVQS-ALPIGAGLGSSAAFAVCIATVALGSIQ---QTSNLELINKWALYAETTMHGTPSGVDNTVGTYGGLIQF--ART---NMTPLLRILLVNTQQSRSTKALVANVRTNFDKF-PSIVPP-VIDLMETIGVQALADLRK-----SLDAEIYERLKFYISANHALLSV-VQVDHPKLVAVRSCAERFGF-GCKLTGAGGGGCAFILLPVAALVHAITNLPFLVWESQGV---------IDTA------- Catan2 -----------ILFGEHSVVYNKLAVATAVN-LRSYA------------------TLTPEARSRLGALHLIDGLLTLRS-EIPIGSGLGSSASLSVAVVAAIMGM----EEVPD--LINAWALIAEKVIHGNPSGVDNTVVTYGGALAY--TKT----MQTLLEFLLIDSKVTKNTMIQVNKVRARRDLL-P-------------------------------------------------------LGHPTLDAIVAMAERHGF-AGKLTA----------------------LGWRVFRGVGVRVSVGMDQWVDKIV------ Cioin KKVKVSAPGKIILHGEHAVVHGKRAIACAVD------VETT---KTDETSLKFKM-------ALTIFLFGYLKVIEVKSQNLPIGAGLGSSAAINVAMATAFLDQIQ--GNDMLLTLINEHAYLMEKIVHGNPSGIDNSVATYGGAASF--QAGRLKNFSYLLRFLVTDTKVSRNTKALVSAVQEKLSQY-PETTGH-ILYAIDEICKTAEKLLANNSQ---------NQLKDLLKINHHLLNS-IGVGHAKLDKIHQLSNDFGF-ACKLTGAGGGGCAITLI------------------------------------------ CocheC53 PPFMVSAPGKVIVYGEHAVVYGKAAIAAAIS-LRSYLVSFL-SKSNRTVQLRFPDSLDPDLMSATSFLYLFLSLYTLRS-TIPIGAGLGSSASISVCLSTALLRALSGPDQPAQIERINRWAFVGEMCIHGNPSGVDNTVSSGGKAVLF--QRRQPPLVQPLLPLLLVNTRQSRSTATEVAKVANLRKAH-PVLAES-ILDAIGSVTESAHKLLTSDSE--SIE--ALRHLGELVTINHGLLVS-LGVSHPKLERIREIIDHTGIGWTKLTGAGGGGCAITILKLDSLEVKLENEGFEKFEGDGVGIEIDQEKFIERLVEGWKFW Coere1 APFVVSAPGKIILFGEHAVVYGKTAIAGSV-DMRAYAVTPR---KDGKTRLFLPDEIETQLTAILTFAYMYGSLICVRS-LLPVGSGLGSSAAFGVVLSTALLGHLKQM-----RKLINHWAYRGEQVAHGTPSGIDNAVATYGGFLAY--TRG----SVSLLRVLITNTQVPKSTKALVASVRTLRERH-PEVVDT-ILDSIHSISTAAGSLFQS--------KPCCSELQDIVRLNHGLLAT-LGVSHPSLERIREITEARGM-ASKLTGAGGGGCALTLIPVDRVAQELGEVGFRCYQGAGVTI---IDKWLSLSPDDYSGI Conco1 EPFVCSAPGKVILFGEHAVVYGKTAVAAAI-NLRTYAYMPR---TDDKIRFSCPDKLDEQIKAIMAFLTLLVRLLTVVS-SLPVGAGLGSSAAFAVCVAGALI------VIQSELEFINYHAFLAEKILHGNPSGIDNTISTYGGVALY--KSG----FELLSKVLLTNTKVPRDTKTLVSKVRDTYNQF-PEVVTP-MLESIDAISKTFKLYYEK-----NVPEDYFSELEKLVELNHGLLAS-LGLSHKSLEHVREVTNKYET-KSKLTGAGGGGCALSLLKINSMQNELLERGWDSYSGPGIAF----QDFLSLVAPNWSFL Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 PAFMVSAPAKVILFGEHAVVHGKPAIAAALS-LRSYLVTTL-SKSKRTVSLIFPDTLDPELLSALSFLYIFLSLYTLRS-TIPIGQGLGSSASIAVCLAGALLRALSGPDQPEELERINRWAFVGEMAMHGNPSGVDNTVATQGKAVVF--QRTKPPSVRPLLPLLLVDTKQPKSTAFEVAKVGALKEKH-PKLVGS-ILDTIDKITRTAESLMDEDSE--ELE--SLQKVGELMTLNHGQLMS-LGVSHPRLERIRALVDHEGIGWTKLTGAGGGGCSITLLRLHRLDEQLCEEGYEKFEGDGVGVEIDLERFVERLVEGWKFW Debha1 SPFLVSAPGKVIIYGEHSAVYGKPAIAAALS-LRAYLVTP--CEDVNDIRLDFPDELVPEIVACLCFLYLYANLFIVKS-TLPIGAGLGSSACTAVCLASALAKHVSAAEKVYKLDFIDSWSLMGEKCFHGNPSGIDNAVATYGGAVMF--QRTKPSVRTTMIKLILINTKVPRSTAALVGNVAQVNRTY-PKCAGS-ILDAMEHLVFEAYQIMIRGKE--EKD-----QLRELVNINHGLLVA-LGVSHPALEKIKIIGDTHGIGSTKLTGAGGGGCAISLVHIQKAIKEFENEGYETFEGKGVGSVFSAEVFVEKALESWRFW Dekbr2 FPFVTSAPGKVIIFGEHSAVYNRPAIAAALS-LRTYLVGK--DEESDYICLEFPDNLDPELIAAYAFLYLFVSLFTMRS-TLPIGAGLGSSASMSVCLASAFGGHIKEASKI-TCNFIDKWSFMGEKCIHGNPSGIDNAVASHGGAVMF--QRRLPSVRTAMMNLLLTNTKTPRRTATLVANVSKLVADY-PKSTAH-ILDAMEDIAREAYNSMLRNAN--GKD-----ELLKLIRINHGSLVS-LGVSHPNLERIKLNCDESHVGETKLTGAGGGGCAITLLRSTELENRLEKLGFESFKGKGVGLV---KNFIEESIGDWRYW Dicdi NIIQVSAPGKIILFGEHAVVLEKTAIASALS-LRTTVFTPN---TNNTLLLDFPDECSELFQGIHTFLFLFCALIKITS-DLPIGAGLGSSASFCVSICAGLLDTYICGGQQQQLNLINLWSLQGEKIMHGTPSGIDNAVATFGKALTF--TRK----YKILLRILITNTRVSRSTKTLVEGVIQRSKLY-PTLIDP-VSNLIDTISSQCIESFNQ-KD-----EKLQQTMDLMFDMNQHLLSGCYGVGHSSIDTIVSITKSLGF-HTKLTGAGGGGCVITLLKLSNLKLTLSSNGFESWEDPGV---------IQK-------- Dmel LKFQVHSPGKVILHGEHAVVYHRPALAAVVG-LGTTLVASFQLELNCTLEIQLPE---ANLLAFISIYYLLAGAVQVDS-QLTVGAGLGSSASFGAALATTFLGHFDRD-----QALISSWAYESERVNHGTPSGLDNTVCTYGGMLRY--VKG--------LNILLVDSRVSRSTADIVAKVRHLGDAF-PQLIEA-IWQACEELVAAAVPLYES----GNAQSSKFEQLERLFQINNDLLKA-IGVSHPKLEQIFTIAFKRGF-FSKLTGAGAGGYVIVLLPYWKLKEELESAGFGVHVGEGLRV-------LDD-------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba EVVLSSAPGKVILSGEHAVVHFKTAIAVSVD-LRTFVVEPF-AGGEATIALDMPDSLSLASVALTGFLFLVRHLVSVHS-TLPIGAGLGSSASYATALSAALLVLLAAP-----RDLVNQWSFRAEQLIHGTPSGVDNFVSTFGGTVAF--RRG----VSMPLRFIVTNTRVPRSTRALVEKVASNLAEF-PTVVGP-VLDAIQGISDAYVELLAPGAD-LDHPCAFLAKFAKLMTINNHLLSS-VGVGHASIDRVADIAGSLGQCATKLTGAGGGGCVISLVPVDAVSTGLREAGFAPFEGPGVLF-------LRSAMSDHKFW Fomme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 PPFMVSAPGKVIVFGEHSVVHGKAAIAAAIS-LRSYLVTTL-SKSKRTVSLRFADELDPDLVSVSAFLYLFLSLYTLRS-TIPIGAGLGSSASVSVCLASALLRTLSGPDQPADVERINRWAFVSEMCIHGNPSGVDNTVATQGKAVVF--QRTKPPNVRPLLPLLLVDTRQAKSTAHEVAKVAKLKQTH-PKLVNS-ILDAMDKVTDAASELIEEDNG--SVE--DLSKVGELMTINHGLLVS-LGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLLRLQKLEERLETENYAKFEGDGIGVEIDLEKFVEKLVEGWKFW Galma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 EPIVVSAPGKAIIFGEHAVVYGKTAIAASV-GLRTFALNPT---RDGKVALVFSDPISDAVRAAIAFLYLYI--VTIRS-LLPVGAGLGSSASFSACVAAGLLNRIPNS-THSATNLTNEWAFMAEKVIHGNPSGIDNSVCVHGGAILY--QKG----LEQLLRFLITNTRVPKDTLVQVANVAKRREKY-PDIFNH-VIDAVQGVSRACIEAVERASRKLPSDSDLYNTIEFLIDTNQTLLVS-LGVSHASLENVRSIGQRYGV-TTKLTGGGGGGCAITVVRIENLLTDLTSQGYEGFVCPGV------RELLEPV---QKSV Gloin1 SRYLVSAPGKVILFGEHAVVYGKTAIAGSLDGLRTYVFEKR---DDGFLELNLPKTINEELLAASVFLYLYASLVHIAS-NLPVGAGLGSSAAYSVCLATGLLGHITIPGFNISMNLINRWAFQAEKIIHGTPSGIDNAVATYGGAVSF--SKG----MENVLRFLLTNTKVPRNTRTLVANVRKLHDKC-PHIVVP-ILEAIEGISSKFKEIINSQKE---LNN---IEAIELIDFNHYLLNS-LRVGHPSIDKVREIAAQYSL-HSKLTGAGGGGCVLTLLRIMKIMLNLTSIGFECFEGHGISI----QEFIQQFS-GWKHF Hisca1 PAFMVSAPGKVIVFGEHAVVHGRRAIAAAIS-LRSYLVTTL-SKSHRTITLNFRDSLDTELLSATAFLYLFLSLYTLRS-TIPIGAGLGSSASIAVCLSAALLRILAGPDQLPEIERINKWAFVGEMCIHGNPSGVDNTVSAGGKAVIF--RRGKPPSVTPILPLLLVNSRQPRSTSVEVAKVANFCKAH-PAVSES-ILEAIDQVTESASNLIQSDKS--SSE--AIDHFGELFRINHGLLVS-LGVSHPRLERIRELVDHTGSGWTKLTGAGGGGCAITLLRLKRLEKTLDDEGFERYEGHGIGVEIDQQKFIERLVEGWKFW Klula1 TPFIVSAPGKVIIFGEHSAVFNKNAIAASVSSLRTYLIEQ--SKDGDGVELDFPDHLCPKLKAALSFLYLYLSLFTVKS-TLPIGAGLGSSASISVCLALAMAGHI---DK--SKEFINHWAFIGECCIHGTPSGIDNAVATYGNAVKF--KRQGSTKFDQILPMVLTNTRIKRSTKILVSGVGDLVNRK-PLITEP-ILEAMNQVALRGSELLSD-SK--DIH---YDELLELIRINHGLLVA-IGVSHPGLEVIKQLSDELKIGQTKLTGAGGGGCAFTLLNVRKFHEKLHSNGYQIFEGVGCCFHLFID--VSLALG-SLTW Lacbi2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele --------------------------MANVS-------------------------------------------VKVRC------PGMGSSASYCCSLALALL-----------ITNVNRISYQGEKVFHGTPSGVDNTACSFGGCLMY--NKTSP------PRLLVINSRQPHNTADIVGQVREQRHKL-----TS-TFKRIGEITREGEERLRA------------KDISSLITENHNLLNKLPGVSNTHTDRIVEICRDYGV-PAKITGAGGGGVVIGIIPLSELISSLKTAGYQVLTVRGVEI-------LSENV------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 -SYFTSSPGKVILFGEHAVVYGKVATAGSL-GLRSYAIQTR---EDKKIEVNLPDSMNTDLLAAIALLYLHSFLFVVRS-NLPVGAGLGSSASYSVCVATALLGYLS--GTGM-RDLVNQWAFQAEKVIHGNPSGIDNTVSTLGGAVMF--KKG----IEPLLRFLLTNTRVPRETQVQVANVRKLHDKF-PTVVNP-MLDAINEISNSCKNIF--QDG---LDAHLLARFGELVDVNHGLLAA-LGVSHPSLEKVREISSKLGL-KSKLTGAGGGGCALTLIRVAVVKQLLEAEGFQCMETHPTTI----TYF-------WTYF Mucci2 ERILVSAPGKVILFGEHSVVYQKTAVAASL-GLKSYLLENR---KDDLIKLVLPDDMPAELKALMAFLYLLIIMVCVRS-FLPVSAGLGSSASYSVAIATALLNKIPVD---RPLEKVNAYAFKAEEVIHGNPSGVDNAVATYGGAKTF--MRG----FATLLRLLLTNTKVPRSTSALVAGVGEKRKKY-PEVVEP-MLDSMHGIAIRCRDAFKKDNE---LTEALMDEIEDLVTLNHCLLDG-LGVSHPSLEKVRSITAQSGL-KTKLTGAGGGGCAVTFIRIDQVMLNLQSEGFDCYQGTGADA----DEWRDTL---EQYF Mydma NKVISTAPGKLILTGEHSVVYGKEALACSLN-LRTECIQTL-K-DNFELCLEIP-DVDPEELAVHVLLFLFSGIVFITS-TLPIGCGLGSSAALAVAVASSLLNLI--------IMLINKWAYLCEKIVHGNPSGIDNAVSIFGDCISF--KSG---N----MKVLIINTGVSRNTKDIVTSVREKSEKF-PMVYHS-LFETMDKVSTTFKNLLTV-----NADKNKSSYFEHLIDINQHLLEA-IGVSHPVVNKVITICKKHGL-HPKITGAGGGGCVYSLV-SVL---DLIINDIKEYDGDGVKL------------------ Neucr2 PTFMVSAPGKVIVFGEHAVVHGKAAIAAAIS-LRSYLVNTL-SKSKRTVTLKFPDEIDQELVSAGSFLYMFLSLYTLRS-TIPIGAGLGSSATIAVCLSAALLRTLSGPDQPPEIERINRWAFVYEMFIHGNPSGVDNTVSTQGKAVVF--QRTQPPSVRPLLPLLLVDTRTAKSTAHEVAKVATLKKKH-PQLVGT-ILTAIDQVTQSSAQLIEENTE--DEE--SLSKVGEMMTINHGLLVS-LGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLLRLDKLEQRLDEEGYSKFESDGVGVEIDLEKFLEKLVEGWKFW Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 PAFMVSAPGKVIVFGEHAVVHGKAAMAAAIS-LRSYLVTTL-SKSQRTITLNFRDELDPELVSASSFLYLFLSLYTLRS-TIPTGAGLGSSASVCVCLSTALLRTLSGPDQPPEIERINRWAFVGELCIHGNPSGVDNTVAAGGKAVIF--RRDKTRTVISLLPLLLVNTQQARSTKTEVSKVGALRDAH-PIVTES-ILNGIDHVTCSAQRLIEDEGI--SET--TLAHFGTLIRINHGFLVS-LGVSHPRLERIRELVDYADIGWTKLTGAGGGGCAITLLRKQDLEQKFDKEGFTTYEVDGVGVEIDQQKFIERLVEGWKFW Phybl2 ------APGKVILFGEHAVVYQKTAVAASL-GLRSYLLEQR---QDGQCHLLLPDSMPEELKAIMAFLYLLVILLCMRS-FVPVGAGLGSSASYSVVLATSLLGHLPYD---STLNKINEYAFKAEQVIHGNPSGVDNAVATFGGAKSF--IKG----FSTLLRLLLTNTRVPRSTSALVAGVGAKRARY-PEVIDP-ILDSIDKVSLRCRDALKKNQE---LTGQLVEELEDLMDINHCLLHA-LGVSHTSLETVRSITAKHGL-KTKLTGAGGGGCAVTVLRIDTVVKSLGTQGYDCYQGVGA-------------------- Picst3 TPFFVSAPGKVIIFGEHSAVYGKPAIAAALS-LRAYLVTP--SQDPDTINLLFPDELVPEIVACLCFLYLYTHLFCIRS-TLPIGAGLGSSALTAVCLASALANRVTSADKILKLDFIDSWSLMGEKCFHGNPSGIDNAVATHGGAVMF--QRMQPSVRTSMIKLLLTNTKVPRSTADLVGGVGKLNVEY-PKTSNS-ILEAMEHLSNTAYQIMVRGAE--ERK-----KLRELVNINHGLLVA-LGVSHPSLEKVKIITDTSKLGSTKLTGAGGGGCAITLVDIAQGIAELEKEGYECFEGKGVGSVFSPEKFIEKVLEGWRYW Plicr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo KQIKVSAPGKVILFGEHAVVLGKTSIATALS-LRTNAVEQI---EEPVLHILLPDECNAEFLGIQSVLFLFSVLIHFSS-NLPMGAGLGSSASFNVCLVTGILEIYACGGTTNNLELINQWSLQGEKIMHGTPSGIDNAVSTYGSALTF--TRK----FKNLLRLLITDTRVSRSTKVLVENVINRHKQY-PSLIEP-VAVLIDTISKECLQAFDQHND-----NQLQKTIELMIDMNHSLLSGCFGVGHSTLDMIASVSKRFDL-HSKLTGAGGGGCAITLLKVNNLKSALKEHGFESWEGQGVII------------------ Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ---------------MHGFIDEKQG-------------------------------------SLLSFLYLLNAMICVRS-FLPVGAGLGSSASYSVVMATGLLGLIPAD---SPLDMINSYAFRAEQVIHGNPSGVDNAVCTYGGAKTF--VRG----FSTLVRLLLTNTKVPRSTNALVASAGQKKEKY-PQIMNP-ILDAMDGISVRCRDAFKGLGE---ITKELMQELGDLVVLNHCLLDA-IGVSHPSLEKVKSITSESGL-KTKLTGAGGGGCAVSLI------------------GVGANA----ESWREEI---QKYL Rhoto1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 VRV----PGKVILFGEHSVVYGKKAIAASIDELAVTAIKSS-TNENFGASYEIANATETNII---CILYIYIFMLIVSS-TIPMGAGLGSSASFSVAIASIFI-----------QDLTDRWAFTLEKIIHGNPSGVDNKIVHYGGLLSYVKQRS---SFQPPLKFVLVDTMIPRDTKKMVNNVSIKFQRR-PKLLGD-SFKKMDEISNKFEQFLKI------FKKMAFSAISNLFSKNQHHLKV-LGVSHPVIEKVITISKKHGH-QAKLTGGGGGGFLVVLINEVYFYKELTLNGFKYYNGKGLQF------------------ Sacce1 LPFLTSAPGKVIIFGEHSAVYNKPAVAASVSALRTYLISE--SSAPDTIELDFPDGLSQELVAAFCFLYMFVCLFSLKS-TLPIGAGLGSSASISVSLALAMAGLI---NDLEKKHIVNQWAFIGEKCIHGTPSGIDNAVATYGNALLF--EKDNTNNFKFLIPMILTYTRIPRSTKDLVARVRVLVTEKFPEVMKP-ILDAMGECALQGLEIMTKGTD--DEANELYEQLLELIRINHGLLVS-IGVSHPGLELIKNLSDDLRIGSTKLTGAGGGGCSLTLLRIDSFKKKLQDDSYETFEGTGCCLSLVFQLFIDDLL---LPW Salro -EIRASAPGKLILHGEHAVVHGKLAVAASLD-LRAS-VLTL-ND-DAKVKLSLAEQLDQPLYAVEALLYLY-----VKS-DLPIGAGLGSSAAYSVCLASSMLRPI----DAAN---INAWAFLSESIIHGKPSGLDNTISCFGGAVSF--ASG-------VLEVVLVDTGVPRSTKALVSGVRERKHEF-PAVMDP-LLDSMGHLSQTFLDISQQ----AETSDPLFTKLETLMTMNHHMLNA-IGVGHPALDDVVRLASSLGL-AAKLTGAGGGGCAYVLLRKAKLFAALKEKGLRYWTGAGVAV------------ANQ--- Schco3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 KSLIVSSPGKTILFGEHAVVYGATALAAAVS-LRSYCLQTT---NNNEIVIVMSDSPNLDLLAMLCTLYLFTSLLTISS-QVPLGAGLGSSATISVVVATSLLGNIEPP---SSLALIEAWSFLGECCIHGTPSGIDNAVATNGGLIAF--RKA---HQSAMLSVMITDTKQPKSTKKLVQGVFELKERL-PTVIDS-IIDAIDGISKSAVLALTS-----ESDNSSAKKLGEFIVLNQKLLEC-LGVSHYSIDRVLQATKSIG--WTKLTGAGGGGCTITLLTFKLCKESLLAHKNSIYDGPGVSV-TDSDSFLSKFN---KYY Sorma PTFMVSAPGKVIVFGEHAVVHGKAAIAAAIS-LRSYLVNTL-SKSKRTVTLKFPDEIDQELVSAGSFLYMFLSLYTLRS-TIPIGAGLGSSATIAVCLSAALLRTLSGPDQPPEIERINRWAFVYEMFIHGNPSGVDNTVSTQGKAVVF--QRTQPPSVRPLLPLLLVDTRTAKSTAHEVAKVATLKKKH-PQLVGT-ILTAIDQVTHSSAQLIEENTE--DEE--SLSKVGEMMTINHGLLVS-LGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLLRLDKLEKQLDEEGYSKFESDGVGVEIDLEKFLEKLVEGWKFW Sphar RSITTSAPGKLILFGEHAVVHGKAAVAAGLG-LRTAVVQVD-RDQDLDVKWSIQEQF-----AAAVFLYLYICTAHVKS-QLPIGAGLGSSAAFSVALAAAMLGQIRNLSNTRNQEIINVWAFAAECIIHGLPSGIDNTVSCYGSAIRF--QRG-------NLKIYLTNTMVPRSTKLLVAEVRRRRDLL-PSVVDP-ILIAVENISLKALDILQT----LKVNSQLFSELECLVDLNQGLLQS-VGVGHPSISNVVEITRQLGF-HTKLTGAGGGGCTMTLIPIAQMNSALRAEGYDVWEGSGVVQ------------PDWLHI Spipu1 --------------------------------------------------------------ASLAFLHLYTSLVCVRS-ALPVGAGLGSSASYSVCIAAGLLGYVKMPNTAY-LKLVNDWAFVSEKVIHGNPSGVDNAVSTYGGAMLY--TNG----MEPLIQFILTDTCVPKNTKAQVENVRIRRVQF-GPILDP-LMDSMQGISNTCKDLFGAQSD---ITSDVLTGMEELVDMNHCILAA-CGVSHPSLERIRQLTARYGL-RSKLTGAGGGGCALTLLRIEKVKSELRAESFRCFECHGVRW----DWM-------WKHF Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 MSLTVSAPGKVILFGDHSVVYDRRAVAASIS-LRTTLFTSN---MDEQITLDFPDSLDLELLAAAAFLYLFFKLYHIMS-ALPIGAGLGSSASVSVIIAATLLGAIELPSKNAQLDLINKWAYVGEQCIHGNPSGVDNTVATYGGAVAF--QKS-------LLPLLLTNTGVPRSTKAQVAGVADLRASF-PPVIEN-ILDAMHQIAIEAQGLLPDNKD----------RIGALMELNQGLLRT-LGVSHPAIEEV--VRDNHTKGWTKLIGAGGGGCVITLLKVSLVSPDSSSSKPEQYLGSGVGFETGVQHY----------- Thetr --VEASAPGKVILFGEHSVVYGKPAVAAAVA-LRT--LTSP-APGTPTLTVELPDPLPLA--AIAAFLYLYIGIVRAAS-QLPIGAGLGSSAAFSACLAAAAM---ASPDETSGLDAINAWAFCAEVVIHGTPSGIDNTVSTFGAAV-----RY----VSSPLSLLLVDTRVPRSTKTLVAGVRAKRDTF-PDVMDP-VLDAMGALADSAVGVLSA-------PDDAVSELGELVETNQALLAA-IGVSHPALATVMTTAARHGFPA-KLTGAGGGGCAIILLPEDALVAELESMVFYNNETPGV---------LR---PTL--- Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 PAFMVSAPGKVIVFGEHSVVYGKAAIAAAIS-LRSYLVTTL-SKSKHTVSLRFPDSLDEELLSATAFLYLFLSLYTLRS-TIPISAGLGSSASISVCLAASLLRTLSGPDQPSEVERINRWAFVSEMCIHGNPSGVDNTVASQGKAVVF--QRTKPPSVRPLLPLLLVDTKQAKSTAHEVAKVGKLNKTH-PKLVGT-ILDAMHNVTDAASELIEDDPK--EEE--SLRKVGELMTINHGLLNS-LGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLLRLTKLDGQFEAEGYQKFSGDGVGVEIDVDLFVERLVEGWKFW Umbra1 GPLLISAPGKVILFGEHAVVYKKTAIAASL-GLRSYLLENR---SDNVIHLELPDDMPAELKAALAFLYLYISLVSVKS-TLPVGAGLGSSAGFAVVLATALLGHIVVPQDRSELSQVNRWAFKAEQVIHGNPSGVDNAVASYGGAKRY--TKG----FASLLRLLLTNTTVPRSTAVLVAGVGDKCRNF-PNVMNP-IMDAVQAISDDCASLFERDGE---VSEQVVTRIEDLFDLNHCLLSA-MGVSHPSLEQVRNITRQHGL-RTKLTGAGGGGCAVTILRVGFFYLS------------SANP----KRLI---------- Ustma22 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 VPFLVSAPGKVIIFGEHSAVYNEPAVAASVSALRTYLVEP--SEDPEEIELDFPDELSQKIVAALCFCYLYVCLFHVKS-TLPIGAGLGSSASISVALSLAMAGHI---DKPE-KKFINTWSFLGEKCIQGTPSGIDNAVATYGNAVLF--KREGTTNFEFVIPMVLTYTKIPRSTKTLVGNVRELVIRQ-PNVIKP-VLTAMGQLALRGTEILDS--D--DKN---YEELLELVRVNHGLLVA-LGVSHPGLELVRFECDTNALGATKLTGAGGGGCLLTILHVQQFKTKLESSGYKTFQGIGCGISLFCQEVIDQLL---LHW [Cluster3558.fasta_al_trimmed; alignment length = 150] Allma1 SD-DDYMSAAFLAAKTSQTYSERRKLKAREAPLRELKESREHGLKRNKGMQLLKKMGFKDGKGLGKRTGIGVEAKRVKLLQFRDWRSTRIKKCRKICYELADTGEIVDDDDPNDPMQLTTLIEYLRTHRYCIYCGCQYDTSCPGSTRDDH Ashgo11 TE-VD-------------VHIDKRRKRRLQDPSSEANDDEYLTMELPKGFQMMAKMGYKTGGVLGTRTGI--PEASV----YREWLHDELARMQKIAFEL-----RGTPSSSTDDEQIAQLHNFLRELRYCFYCGTKYANHCPGFTEDDH Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 DS-DDYLSEKFLAPSKPQTYVERRRAAQRERSRREEEESRKEGLSTNKAMAMMLKMGFKPGQSLGARKGVGLAAKVARIAAYRGRAREGMAAAQRTCKSLAMRLRDSGDGELIQQDRLKTLLGYLRQYSYCFWCGAEYEDHCPGPDEEDH Batde5 DE-DDYMSEAFLSGSKKRTYSERRREALARMPVKEAQQQFELGLQTNVGYKMLLKMGYQKGESLGTKSGLGTTHAR-----FRSKMNEQLKKARMSVMTMQ--------------ERLRLVNEYLRQYYYCLWCGSVYADQCPGDTFQCH Botbo1 EE-DDYLSEKFLASNGRKTYAEIRRQAQREKSRREEEEARREGLGKSKAMAMMMRMGFKPGQSLGRRKGVGLSSKIPKIFDYRDRTREELGGALRTCVALEDRLRDPDDDSVVDDDRLSQVLAYLRSHLYCFWCGTRYVSDCPGEAEDEH Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel DE-DDYMSAEILRAHKREQINSRFEESR--KPKRPEKERRDEALAKSKGFALMAKMGFKPGMTLGKRKGLGHKMKEQAAKHYSKRRKLDIRSCRKVCEEL-YKVAKEDEEE----EALSTINNYLRGHFYCIWCGANFSSHCPGSTRRAH Canalb1 DN-SETESDK--KSRKKQKY--------------QQDDKHEEPTESSIGLSIMERMGFKIGNALGNRQGLGG---------LKLNLANSLKKIMKLCFELSAAVG-FERE--VENQTLSDLLNYLRTHNYCWYCGLKYNDNCPGKTRDIH Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 EE-DDYMSAAFLASSSSSTYSQRRKL-ALQPPGSAIQEKRNEGLKRNKGMSLLQKMGWKEGAALGKRLGIGVEAKRIRLLQFRDWRATKIRKARKICFQL--------DDDEIE-EQLAQLISTLR------------RTVCPGLTRDDH Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Conco1 ------------------------------------------------------KL---PGEGLGV-KGL-----------FADEEKEKISQTE----FL---------------EQLDRKVN-ITNPLWTPYSK-HTQAQANGIEEEEE Conpu1 EE-DDYFSDKFLASRSAGTYSQRRRDAQLKKSRREEEEARRMGLETSKALSMMMKMGFKPGQALGARKGIGVLAKVARTKEFRER----LASASRTCVTLAERLREDDGDETVAQDRLRELLAYLRRYSYCLWCGTEYDGNCPGPTEEEH Copci DE-DDYLSAKFLTKSTVKTYSQIRKDAEKRKSRREEVEAREEGLSKNKALSMMMKMGFKPGQSLGAKQGIGLLAKIAKLAEFRERARENLGPAQRTCATLREGLKNDEDDEILEEDRLRLVLSYLRRHNYCFWCGIKYENQCPGPEEDDH Croqu1 DE-DDFMSDKFLSTSKQPTYSDQRKRKQLDRSRAEEIEAREEGLSRSKAVQMMLKMGFQPGKGLGARSGIGVGPHVPMTEEFFQNSKAKLARARRTCEELEEVMR-GDPNEDTVDSRLLYTLQYLREHFYCIWCGCQYSSECPGEEEDDH CryneH991 SE-DDFMSDKFL------NYSARRAKESLKLKLKDEEQRRKEGLETNKAMEMMMKMGWKVGEGLGKRKGLSATAKMEQLGRFRDRQRVEGKKARELLVEMAERLREGEEGVDYKDTYVTFTVDQLREHLFCFWCAYKYKSGCPGEEEDDH Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 D--SDSDSEY--VNTKRKKYSTENKEGIDHMKYDEQQVKREEALNQSIGLSIMEKMGFKVGDSLGNRLGIGA---------YRDRIQKSINKAMKICFELANRLNNLDKD-LLSEDKLERLLKYMRSHHYCFYCGCSFKDSCPGIHEEDH Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel EE-EDYMSDKFLRGRKRQEVESKKDELKKRDNVR-----LQQSLNKNKGFQLLAKMGYKAGSGLGIRGGLGRNKAGIKSDEYRRRATHKIKRCQQTCESLKPKDE---PE-----EQLELLTGYLRAYCFCYWCGTHYDDNCPGLTRDEH Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------ Falba EE-LDYMSDAVL------AAEDALQKSRSL--TKKAMDALRDGMQKPPAPIQVDLDRFELGHRLGL------MPAEP----YAERVFQAERAARKLCFRL-----SPAPGSDMPEDRLSEVNEHLRRHTFCIWC------QCPGPTRDLH Fomme1 DE-DDYTSDRFLATSASLTYAQRRKQAQKQKSRREEAEAREQGLQQNKAMDMMLRMGFKPGGALGRKKGVGLASKSARIDEYRIQARSALSAASRTLIALSERLRDGDDDETIDQERLKRVLGYLRKYHYCLWCGTQYNDNCPGEDEEAH Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 DD-DDYLSDKFLASSAKKTYSQLRKEAQKRKGRRQEIESREDGLSKNKALNIMMKMGFKPGQSLGNRKGIGLLAKMAKMAEFRDRARDELTPAQLTCTTLQTRLRNPDEDELLEEDRLHLVLSYLRKHAYCFWCGVKYEGQCPGPEEDDH Ganpr1 AD-DDYMSDTFLDSSAKDPYSKKRRLDIQSISPAIEIEGRERGLNENLGFKMLQRMGWSQGNALGKRTGLGILAKERRARDFQDVIRNRVEMARRIIRDMESGEGNGEDDNGFDEEQLSELLGYLRTHLYCLYCGTRFDSECPGESRDDH Gloin1 ------MSSKFLPPEPSHTYAERRRRKQLLKPRREENDYREQALAKSPGLKLLKKMGYEQGKGLGNKLGLGMVAKRAKFEEFRERVRQELRKLQNICETL-----NNNNDQVVEDEKLDRIFRYLRTYYYCFWCGCEYGSECPGYEEEDH Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 ER-LQ----------------RPLKKSGKL--RDQPWEENYLTMEIPKALKMMKSMGYNIDETAESRIGI--VANVD----FRERINNELKHMQKLAFTLHKSLGEQSSN-----EKIKKLNTFLRELRYCFYCGNKYKDHCPGFTEEDH Lacbi2 DE-DDYLSDKFLTS---KTYSSLRKEAQKKKSRRQELESREEGLGKNKALSIMMKMGFEPGRALGSRKGIGLQTKLAKADEFRDRAREELLPAQRSCATMQSRLRDADDDQCLEEDRLVLVLSYLRTHFYCFWCGVKYENQCPGPDEDVH Lenti61 DE-DDYLSDKFLASSSSASYADRRKEALKQKSRREEREAREEALNRNKALAMMMKMGFKPGQALGKKKGIGTLAKMAKMVDFRDRAKQELRPAQRTCATLEGRLRDVDADEDLQEDRLTLVLDYLRKYAYCFWCGTQYEDNCPGPDEDAH Malgl1 EQDIDYMSDTML-----------------------EKLAANE---R--------------------------RRQ------AEARQREK-----------GPAIGSYKDDQ-------VDAFRQLQKHL-----------ARSTCRALDE Mellp23 EE-EDFMSDKFLNTSSTSTYSDKRKRKQIEKSRAEEIEAREEGLRNSKAVQMMLKMGFQPGKALGKRGGIG-KPHQDLNEDFFEKSKSKLSKARRTCQELDEVNG-KDPNEDISDSRLIHTLRYLREYFYCIWCGCQYDSECPGEDEDDH Mnele ME-DDYMSDSFLRGVGKREVHKRNEECKRIKSKKLAKNKLIKGLETNPGFKMMQKMGFKQGIGLGKSAGLGQ--RLDAYKRFRESKSQQVRKCQNVCRQM-----QDDQEEDEPD--LPQLDAYLRQHSYCVWCGVKYVSHCPGDTQEAH Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 EE-EDYMSEAFLESTKSKSYSERRRQKEREKPLHVEKEAREQGLEKNKGMAMLLKMGFKKGGTLGARGGLGMVHR---VFDFRGQKRDQLGAARAICMRLQDQDKDEDGDQGVDEEKLEEVVAYLREHSYCFWCSAQYDGNCPGKSEDDH Mucci2 DE-DDYMSTKFLESK-RQSYSEKRKRQLREKPRAQEAEEREKGLQKNKGMKMLMKMGFKQGQGLGSRSGIGMMRKRVHIDPFRNQMASKINAAVSICERFDNEQSQEGEDEQVEAEQLTKLVDYLRTYFYCFWCRAKYTDNCPGTSEDDH Mydma DE-NDYMSDKFLQDHKPGQKHKKIEEGKLKKPIKLEIEKRNEKLNENKGFALLSKMGFKKGMGLGKRKGLGTMSKKRKMVEFEHRMKERLYKSQKACQHL-IK--EEDDD-----SKLKILTSYLRTHYYCIWCGSTFKDYCPGDNFEVH Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 DE-DDYMSTKFLDATNQQTYSEKRRKHLHNKPRAQEQEAREEGLKKNKGMKLMMKMGFKTGMTLGKRQGLGMASKRVALDPYREAMAERIGACASLCKKL-----TEGEDEALKADKLDRIIAYLRKYVYCFWCGARYDSNCPGEQEDDH Picst3 D--SESDSD---VSTKKVTFVPA-KEKVSTMKYHEQQTKREEALKVSVGLSIMEKMGFRIGDTLGTRLGLGA---------YKLRVSDQLSNVMKLCFEISVKISSIDN---IEDSAMISLLQYLRNHFYCFFCGCSYSDHCPGIFADDH Plicr1 DE-DDYLSDKFLPPPAPKTYAERRKEAERQKSRRQELESREEGLSKNKALSMMMKMGFTPGQALGKKKGIGLVAKMAKMAEFRDRTRQELGPAQRTCVTLQARLR-DDLDETVAEDRLHLVLSYLRKYAYCFWCGTQYDDKCPGADEDAH Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 EE-EDFMSDKFLETSTENTYSEKRKRRLIDRSRVQEIEAREEGLSRSKAFQMMLKMGFQPGNSLG-RAGIGIKGKMDLTEEFLATSRTRLGRACRTCEELAHLTRQNDPDEDLEDTRLSCTLGYLREYFYCIWCGCQYESECPGEEEDDH Punst1 EE-DDYLSDKFLATKTTKTYSQRRRDAEKEKSRREELESREEGLSKNKALAMMMKMGFKPGEALGKRKGIGLLAKKSKLSEFRDRARRELTQAQRTCCSLEFRLR--DKDEAVEQDKLGMVLDYLRKYSYCYWCGTQYVDNCPGPTEDDH Rhior3 DE-EDYMSLKFLENENKKSYSERRKRQLREKPRHIEQEERERGLQTNKGMKMLMKMGFK------------------------------------------------------------------------------------------- Rhoto1 SD-VDFDDPRFLSTSSAPSYQDRRKRKLIEKSRKQEEEKREVGLRTSKAFRMMSKMGFKPGEALGRRTGLGVYARDAHYASYLSRLRSTLRSARRTCEELERDEE-SDEEEEAESTRLALTLTYLRKYNYCLWCGCQYDDNCPGEAEEDH Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 DR-ID-------------KNTPPQKKSKRD----------------PRGYKMMENMGYKEGETLGSRRGI--MQMSE----FIKRESEMWYRIQKVAFEMKNDLNNEDKNIDCDTKRITKLNIFLREKYYCFFCGIKYKDHCPGVNEDDH Salro ------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 EE-DDYLSDKFLAPEKPQTYSQRRKEAEKRKSRRQEQQAREEGLSKNKALAMMMKMGFKPGQSLGRKVGIGVIAKMAKMADFRDRARQELKGAQRTCYNLEGRLRAEDEDSTLEEDRLYLVLSYLRRYSYCLFCGTQYDDNCPGPSEDDH Schpo1 ---------------------------------------------------------------MELYKGIML---------LADLEKMKIS--------LESAIK----------KQLDVVLHLLRRFLYCLYCGCHYDSNCPGINEEDH Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar SEHKRQKSASAL-----------------------EKERREEGMSKNKGFHMLSKMGYKPGDGLGKKSGLGMRTKNEA---FQARMRRQLHTSCQVCEQLADTIATGVDDASITVQWLVDVTKYLRKHLYCNWCGRTYENQCPGPTAEDH Spipu1 EEVEDYMSDALLESRSAPTYTKRRAEKLRRKPLKEERESRERGLQSNKGFQMLAKMGYKKGMSLGTRQGIG-QQRALEHEQYRMLMNKRLRKARLQCEHL-----PLEEE-----LQLMAVTIYLRLHYYCLWCGEAYPTTCPGDTAESH Sporo1 SE-PDFDDPRFLSTHEQ-SYADKRKRKMMEKSRKQEEEQRQLGLEHNKALKMMQAMGFKPGDSLGKRTGLGI----SRIDSFLSHIRQTLKSCRRTLEELERELASSDDDERTERTRLALTMSYLRHYQ--------------------- Stehi1 DE-DDYLSDKFLAPSTSRTYSDKRREALRKKSRREELEAREEGLSKNKALAMMMKMGFKPGQTLGNRKGIGLLAKAAKVDEFRDRTRRELIPAQNTCVTLHERLRQQDADEVVEEERLGRVVEYLREYSYCFWCGTQYDGQCPGPDEEQH Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 SE-DDFMSDKYL------SYSSQRQAQTLKVPLRQEAERRSEGLNTNKAMEMMMKMGWSVGESLGKRKGLTAPEKLQRLGEFRERQKRGAEKAREKLVEFAERVRPSDEIEEWEGEYPAYLLSQLREHLFCFWCGYKYSSGCPGEEEDDH Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 DE-EDYMSLKFLEDQ-KESYVEKRKKALREKPRRVEEEARQEGLKKNKGMKMLMKMGFKQGMTLGKRGGIGHLAKKPKIDPYREQIAARIIAAARIIEKLDIGEAKSADDDHVQQEQLSDLVSYLRNYYYCFWCGAKYADNCPGPAEDDH Ustma22 DE-DDFMSDKFLTTQDKRTYTNRRRRLEAHKSNKEEEQARQEGLDRAKAMRMMLAMGYRRGEALGRRAGIGMSSRQSVAEPFRTRISSALSRARQALIHLVDIYRQTDPSSNQQQNQLVLVLDCLRDHLYCLFCGCQYTTECPGEEENDH Walse1 ------MDDAFLESKGKHTYGEMRLQAIKDASKKQEREKIEEGLERNKALNMMMKMGFKPGQSLGKRSGIGVAAAASNALNFRLRKTYELKQLRTTIKNAAQRLKDGDEYEVVQQIRLKFTQEYARVHYYCYWCGTKYDSNCPGFDEDDH Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3565.fasta_al_trimmed; alignment length = 185] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 HFIYQPCYCTSEMDRSDMLAMVPASCGWRSGRCD--VCLKEGMVYWEIELVRFGIGRRE--CSLDTPVGCDFYGYGIRDNQLESVHDGKLSLKPGDRIGLLLMLPRDHIAIRYKNQLFFESTDYVRTTGSYLKVFLNGAFEGLNNGRLGYYPMVSCFNGGVVRIITRSELKYHTLEELHQQQTGE Aspfu1 GFRYSYAYRQTDEDSPAAIFFVTASSAWHTARAN--VCAREGAYYYEARVVRLGFARRE--ADLDANVGVDCYGYGIRDVNGEVVNRMRCEIREGDVIGMLITLPRDRIPFHYKSDFCWQQSNVFSTKGSSITIFKNGPFKELDDGMIGYYPAVSCYGGGAVECRFEGPWWVRGIGERFNEQIVE Aurde31 -YRYTDAFHSQQEDRSPHIRVLAGDRGYRSARLN--VPVREGKWYLEVLVVRLGWARRE--APLEAPVGCDGYSYGFCDKTGHKTTLSRPKFGSDDVIGMYISLPRKRQAVLLKNRLYFEQAEYPQSKQARIAFFVNGAFEDIDDGSLGYYAMISLFNSGRVNINPGPDFKYRPLCERYPEYWEE Batde5 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 NFRYVPAFRTLEEDRSPFVKVLTGEKGFRSARCN--APVKEGKWYLEVKIVRLGWGRRE--APLNGPVGLDGYSYGMRDMTGEKVTLSRPRFGTGDVVGLYISLPRKRIPIQYKGQLYFESMDYPASKDSSIAFFVNGAFKDIDDGSLGYYPFISIYGGARVRINPGPNFDFRPLCERYPEYMAE Botci1 NFRYTRGYRQTEEDSAPHMMMITTDKGFRMAKAN--VGIREGRWYWECKIVRMGFARRE--AAQDAPVGFDAYSYGIRDVAGQKVWMSRPKIYEGDVIGLEINLPRDRVPIRFKTHLYFEQIEYSTCKHSSIKVYKNGPFTDLDDGMLGYFPAVSVFRGGAAEVNFGPQWWYRAASDRYDEQIVE Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 GFKYKHCYSTTDFDRSSGILFITTAQGWRSSRTN--VCIREGSYYFEFKIVRIGVGRKE--ASLEAPVGFDGYSYGLRDVDGQFMTISRR-FKTGDVIGFLIQLPRDQIPIKYKNALYYEQYEYTTTKNSKIRLFKNGPITDLDDGTLGYYPMLSAFQFGVVNLNAGPNFEFKPLSDRYNEQVVE Cangl NFIYRPCYCTTEQDRSYGMSVVRAKDGWRTARSD--VCIKEGDVYWEVEVVRVGISRRE--ASLEGPVGFDSYGYGLRDFSLESIHDGQLELKNGDRLGFLVSLPRDHIPIRYKNQLFYEATDYVKTTGSYVAVFLNGAFEEVNNSKLGYYPTISCFKGGAARLVTTSELRHAVLDDLYRRQIAD Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 GYKYTHCYRQSDEDCDRWFHFVSQEKGWRMGRGN--VVAREGRIYYEVKVVRMGWARRE--APLDAPVGFDGYSYGITDARFEAQHRSRASVQEGDVIGLEIQLPRDRIPVPYKGNFYFEQLDYQVTKHSHIKVYKNGAFENLDDGMVGYFPAISLFNGGVAQVNFGPDFWCRAIGERYKEQIAE Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci -FRYVPACRTIEEDRSPFLRVLAGFRGFRSARCN--APVREGKWYMEVKIVRIGWGRRE--STLNGPVGLDGYSYGYRDKTGEKVTLSRPRFKSGDVVGMYISLPRERIPIDLKGQEVFEILEYPVSKGSKIAFFVNGAFEDVDDGTLGYYPMISLFNDAIIRINPGPDFDFRPIIERYPEFMQE Croqu1 GFRYLACYYTIEEDRSNYVYIVTTDRGFRSARAN--LPIRQGRIYFEVILVRIGLARRE--SGLNGPVGIDGYSYGIRDKTGEKVHLSKLQFGSGDVIGVYVDLPRRRIPIRYRRQLYFESPEYPASKGSKLVFFKNGAFKDLDDGTMGYYPCVSVYGGGIARLNPGPDFKFQALSSLYPVYMAE CryneH991 NFRYHPCYRTIPLDRSSYLRIIYNDRGFRSCRTN--VSVREGTWYYEVHIVRLGWGRRE--ANLDTPVGCDAYSYAIRDVGGEKVHISRPKFKTGDVVGCLITLPRQRRAFNYKSQAYFESAEYTPSKSSSISFFINGAFTDLDDGTLGYYPMVSCFGRAKATCNFGPDFAHRPMCERYAEFKEE Crypa2 QYYYTHCYRQTEEDAATHLFFITTDKGWRMSRAN--VAIREGTWYWECKIVRVGFARRE--AAIDAPAGFDAYSYGIRDKEGQKVYMSRPKIREGDVIGLEIGLPRDRLPIRFKAHIYFETPDYHTTPKSWIKVYKNGAFNNLDDGMLGYYPAVSVFRGGAAEVNFGPKFWYRPMVERYDEQIVE Debha1 GFKYKPCYSTTDFDRSQGIIFVSTLQGWRSVRSN--IGVREGKHYVEFNIVRIGFARKE--ASLEAPVGFDGYGYGLRDLNGQKITLSRPMFKSGDVIGMLIELPRDQIPIKYKNALYYEQYEYTTTKNSKISVFKNGMFENLDDGSLGYYPMLSVFQDGVVGINPGPDFKFRPISERYNENVVE Dekbr2 GFKYTPCYSTTDFDRSQDTSSATVEHGWRSCRTN--IGFREGKWYVEYKLVRFGIARKE--ASVEAPVGYDGYGYGFRDKRGEKVHLSKPIFHSGDVIGLLVELPRDAVPIKYRNKLFFEQYEYTYSMNSRITLYKNGAFEGLDDGSLGYYPMVSCFDGGRVRINTSEDLKQQLFSSRYNGVIVE Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba GYRYCWA----EEDRASVIRLVCRRRGYRSIRATHFAGPGAGTLYFEVRLVRVGVSTRH--GALDAPVGADAHGFGLVPHAGTVVHDARCRYRAGDVIGILLHLPRERVVIVMKNHLFFEDPPNALSTPGSLSFLHNGAFTNL------FSPTISLYYGARVSVNFGPIFDRRPFSERVRDSAIE Fomme1 NFRYIPIFRVIEEDRSAFMKVLCGEKGYRSARLN--VPIREGKWYFEIKIVRLGWGRRE--AGLNCPIGADGYSYGYIDKDGRKVTLSRPRYGTGDVIGMYISLPRVGIPIPFKGRAYYEIPEYPQSKGSHIAYFVNGAFQELDDGWLGYYPFVSLFNGARVSINAGPDFEYRPLCERYAEFVTE Fusgr1 SFRYTHCYRGTEEDSAGHVYFVTTDKGFRMARAN--VAVREGRWYWECKIVRMGWARRE--ASLDAPVGFDAYSYGLRDVAGEKVHMSRPKIREGDVIGLEIQLPRDRVPIRFKAHTYFERVEYHPVKNSCIRVYKNGPFEDLDDGMLGYYPAVSVFRGGAVEVNFGPDFWYHPVSERYHDQIAE Galma1 GYRYIPACRTIEEDRSPFLKVIAGSKGFRSARCN--APIREGKWYMEVKIVRLGWGRRE--APLNAPVGLDGYSYGYRDKTGEKVALSRPRFGTGDVVGMYISLPRERIPIDLKGQEVFEILEYPQSKNSRIAFFVNGAFQDLDDGTLGYYPFISLFNDASVCLNPGPDFDFRPASERYPEFMQE Ganpr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Hisca1 GFRYTYAYRQTDEDSPAAICFVTTNEPWHSARAN--VCAREGSYYYEARVVRLGFARRE--ADLDVNVGVDCYGYGIRDVNGEVVNRMRCEINEGDVIGMLITLPRDRIPFHLKTDFLYQQSHIFPSKGSSITIFKNGPFRDLDDGMIGYFPIVSCHGGGAVEARFEGPWWVKGFGERYGEQVVE Klula1 NFMYQPCYCGTDMDRSDKLAFVSENCGWRSVRSD--VCMKEGKIYWEVEVIRCGISRRE--ASTETPVGCDFYGYSIRDKGLQVIHEGRLHMQAGDRIGFLLTLPRDQIAIRYKNQLFYESTDYVKTTNSSFEVFVNGAFEGLNNNRLGYYATLSSFQGGTASIITEMELKFKTLNDIYNEQIAS Lacbi2 GFRYMPACRTIEEDRSPYLKVIAGSKGFRSARCN--APIREGRWYMEVKVVRLGWGRRE--APLNGPVGLDGYSYGYRDKTGDKVTLSRPRFGSGDVIGMYISLPRERIPIDLKGQEVFEILEYPQSKNSRIAFFVNGAFQDLDDGTLGYYPFISLFNDASVRLNPGPTFDFRPTCDRYAEFMAE Lenti61 NFRYMPAFRTIEEDRSPFIHVLQGEKGFRSARCN--APMREGRWYMEVKIVRLGWARRE--APLNAPAGYDGYSYAMRDKTGEKVHLSRPRFKTGDVVGMYICLPRERIAIEFKGQEYFESLEYAQSKESYIAFFINGAFQDLDDGTLGYYPFISLFNGAQVQINPGPDFIFRPACERYPEFMQE Malgl1 GWRYVAAYRAIDQDRSAFTRIVGTDKGYRSARTN--VGVRHGAWYVEVEVVRVGWARRE--ASLNAPVGCDAYSYGFRDQNGACVTQSRLVFGPGDVVGMYIRLPQKRIPIRYKGQLYFESLEYAPTRDSCIGFVVNGAFVDMDDGMLGYYCMASMYGGARVRLIT-SNFKFRPLAERYAE---- Mellp23 GFRYLACYHAIEEDRSNYVYIVTTDRGFRSARAN--LPIRQGRFYFEIILVRIGLARRE--SGLNAPVGIDGYSYGIRDKTGEKVHLSKLEFKSGDVIGVYVDLPRRRIPIRYRRQLYFESPEYPISKGSKLAFFRNGAFQDLDDGTMGYYPCVSVYGGGIARLNPGPDFKYQALSELYPVYLAE Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mucci2 GFKYSPCYRQAEPDKSSYVSVVTTDKGFRMCRAN--VGVKEGNWFWEARITRIQTNTFDCVACLNAPVGYDAYGYAYRDKTGDKMFCSRPEFQSGDVIGLYISIPRRRIPIAYKERFWFEEKDYRPSKGSFITVYKNGMFTDLDDGTLGYYPAVSVFKGGVVNCNFGPHFQYKPLSERYDEYMVE Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 AFHYTHCYRQTEEDSASHVYFVTTDKGFRMSRAN--VAVREGRWYWECKVVRVGWARRE--ASLDAPVGFDCYSYGIRDVAGQKVHMSRPKIKEGDVIGLEIQLPRDRIPIRFKQHIYFEKIDYHTTKNSYIKIYKNGPWTDLDDGTVGYYPAVSVFRGGAVEVNFGPDFWFRPVSGRYEEQIVE Orpsp11 --------------------------------------------------------------TLHGPVGYDSYGYGYRDKTGEKLHESLPTYRTGDVIGCYISLPHKRKIIKYKKRLYSETNDYLPINNSKIVFYKNGAFKDIDDGSLGYYPSISLFKGGSVTLNFGPEFKYKPLCDRYDEIQIE Pench1 GFRYSYAYRQTDEDSPAAISFVTTSDAWHTARAN--VCAREGTYYYEARVVRIGFARRE--ADLDVNVGVDCYGYGIRDVNGEVVNRMRCEINEGDVIGMLITLPRDRIPFHYKSDFCWQQSNVFSTKGSSITIFKNGPFKELDDGLIGYYPAVSCYGGGAVECRFEGPWWVRAMGERFNDQIAE Phybl2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 GFKYKPCYLTTEFDIAPGVVHVSTQQGWRSVRTN--CGIREGKYFFEFNIVRIGLGRKE--ASLDAPVGFDGYSYGLRDVNGEFITLSRP-FKTGDIVGFLVEFPRDQIPIRYKGALYYEQYEYTNTKQLRIRIFKNGTVHDLDDGSLGYYPMMSVFQNGIVGINAGPDFKFKPLSDRYNEAVVE Plicr1 GFRYIPAFRTIEEDRSPFIKVLLGDKGFRSARCN--APIREGRWYMEVKIVRLGWGRRE--APLNGPVGLDGYSYGIRDKTGDKVTLSRPRFGSGDVIGMYICLPRERIAIEFKGQEYFEAVEYPQSKDSYIAFFVNGAFDDLDDGSLGYYPSISLFNDARVEMNPGPHFKFRPVCERYSEYMHE Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 GFRYLACHYTIEEDRSSYVYVVTTDRGFRSARAN--LPIREGQWYFEISIVRVGIARRE--SGLNAPLGIDGYSYGIRDKTGEKVHLSRPQFGSGDVIGILIDLPRKRIPIRYRRQLYFESAEYPISKGSKVAFFKNGAFRDLDDGTLGYYPCVSVYGGGIARLNAGPEFKFKPLSELYPIHLAE Punst1 RFRYYPACRTIEEDRSPFLKVLLGDKGFRSARGN--APVREGRWYFEVKIVRLGWSRRE--APLNAPVGVDGYSYAYRDKTGEKVTLSRPRFRSGDTVGMYIALPRNRIPIDFKGQEYFETLEYQASKDSCLAFFVNGAFRDLDDGTLGYYPTLSLFNDARVRLNPGPDFEYRPLCERYPEYMAE Rhior3 GFKYIPCYQQAEPDKSPYVSVVTTDKGFRMCRAN--VGVKEGNWFWEAVIVRIGFARRE--ACLNAPVGYDGYSYGYRDKTGDKIFCSRPEFQTGDVIGLYISLPRRRIPIAFKEHLWFEEKDYRQSKGSYITVYKNGMFTDLDDGTLGYYPAVSVFKGGVVTCNFGPEFQYKPICQRYTEYVAE Rhoto1 GFRYTPCQRSIEEDRSLFTLLLTTDKGWRAARSN--IGVREGAWYWEVRIVRVGVGRRE--SPLNAPVGIDGYSYGYRDKSGDSVTLAQPTYGSSTVIGIYLALPRKRIPIRYKGQLYFEQLEYAPSKGSKVAFFVDGAFEDLDDGALGYFPMASVFGGGIATINSGPDFAFRPLCDRYDEYNAE Rozal11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 HFVYRPCYGCTEMDRSEGLSIVPDQYGWRTARSD--VCIKEGMTYWEVEVLRFGVCRRE--ASLEAPVGFDVYGYGIRDISLESIHEGKLNLKEGDKIGFLLSLPRDQIAIRYKNQLFFEATDYVKTTDSYLAIFQNGAFENLNNNKLGYYPTISCFNGGTARIISEDKLEYNTLDTLYKEQIAE Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 GFRYTPALRTIAEDRSPYIGILEGFGGFRTARCT--APMREGKWYMEVEVVRLGWSRRE--TLLNGPIGLDGYSYAYRDKTGDKVTVARPRFKTGDIIGMYISLPRVRIPIDYKGQEVFEALEYKPSPGAHIAFFVNGAFEDIDDGTLGYYASVSLYGPARVRLNPGPDFKYRPASERYDEFMAE Schpo1 GFRYSPCYREIEHDISTPVFIATVEKGFRMARSN--VFMTSGEWYFEIKIVRIGVSRRE--APLDAPVGYDAYSYGLRDLGGQKVHMSRPRFGTGDIIGLHISLPHDRIPIRYKGQLYFEQPDYVPSKGSFIKVYKNGAFENLDDGSLGYYPSISMYGGGIARFQFGPQFSHRPVSERYNEQIAE Sorma AFHYTHCYRQTEEDSASHVYFVTTDKGFRMSRAN--VAVREGRWYWECKVVRLGWARRE--ASLDAPVGFDCYSYGIRDVEGQKVHMSRPKIKEGDVIGLEIQLPRDRIPIRFKQHIYFEKIDYHTTKNSYIKIYKNGPWTDLDDGTVGYYPAVSVFRGGAVEVNFGPDFWFCPVSDRYEEQIVE Sphar -------YMSVHADKTTRRPNGTAHPPGRTS-------------------VRLGWSQSY--ALHQGPVGYDHFSYSYRDKSGSKFHRSLGQYETGDVIGCLIHMPTEMLIVDFKGIPYYQITD-------------------------------------------------EPVEGR------- Spipu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 GFRYTPAFRTIEEDRSPFVRVLLGDKGFRSARMN--VPLREGKWYVEVTVVRLGFGRRE--APLNAPCGLDGYSYGIRDKTGEKVTLSRTRFGVGDTIGMYISLPRERIAIDFKGQEYWESLEYPQSKNSQIAFFVNGAFRDLDDGSLGYYPLISLFNGARVRINPGPNFAFRPLHERYPEYMDE Tapde11 GFKYTLCYRQVESDMSPYMYLATTDKGFRMGRAN--VGVREGQWYWEVKVVRLGIARRE--ASLDGPIGFDGYSYGIRDKGGEKMHLSRPRFGTGDVLGFHLTLPRDRIPIRYRQQLYFEQFEYTSSKGSSLNVYKNGAFDDLDDGSLGYYPAISVYAGGSARLNFGPTFECKSMSARYDEQVAE Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 GYRYLFCYRTLPLDRSPFLRLCTAERGFRSARSN--VSVRRGTWYYETTIIRIGWGRRE--ANLEAPVGMDGYSYSIRDVGGEKVHMSRIKFEEGDVVGCLIGGRRKRVVIKFKGGTYFEMEEYPVVKGSRIEFFLNGAFEDLDDGTLGYYPMVSCFGKGKLRVNFGPDWVYKAMIHRYSEFRKE Trire2 NFRYTPCYRQTEEDAATHVFFVTTDKGFRMARAN--VAVREGRWYWECKIVRMGWARRE--ASLDAPVGFDAYSYGIRDVAGEKVFMSRPKIREGDVIGLEIQLPRDRVPIRFKAHTYFEKIEYHTTKNSHIKIYKNGPFENLDDGMLGYYPAVSVFRGGAVEVNFGPDFWYHAVVERYQEQIAE Umbra1 GFKYTPCYSQDDTDRSPYASILTTDRGWRMCRAN--VGVRQGTWYWEATMVRLGWARRE--ASLDAPVGFDAYSYGYRDVTGEKLFCSRREFEVGDVIGLLIRLPRRRIPIAYKDALWFEEKDYRQSKNSQIEIFKNGMYDNLDDGTLGYYPAVSVYGGGVVSCNFGPNFQYRPMSDRWDEYMAE Ustma22 GWRYTAAFKTLVSDRSPFTKIVSTDKGFRSARTN--IGVRQGEWYAEIEIVRLGWGRRE--APLNAPVGFDGYSYGLTDKAGDKVTLSRPLFKAGDVVGMYIKLPRERIAIRYKGQLYFESLEYPRTRGSKIGFFVNGAFRDLDDGELGYFAFVSSYGGARAKLVTGNGFRFKPLSARFEEHLHE Walse1 GFRYYACFRQNQQDRSPHVELIISNSGYRSARTS--EPIRSGTYYYEVKIVRVGVSRRE--AESGAPVGYDGYSYGWRDINGHKVHLSRSQFTTGDVVGVLVHLPKTRIPIKYKELLWFELSEYPHTKGSFIEFFKNGAYTDLDDGTCGYYPMVSLYKGGQATLNPGPEFAYKPLSDRFGEFWEE Zygro1 NFVYRPCYCCSEMDRSDGVSLVSNSMGWRTARCD--VCIKEGLTYWEVEVVRLGISKRE--ASLESPVGFDSYGYAIRDTSLESIHEGKVALKPGDRLGFLLQLPRDHIAIRYKNQLFFEATDYVKTTDSFLAVYLNGAFRDLNNNKLGYYPTISCFNGGTARIITTQDCKYKLLEELFDEQIAE [Cluster3567.fasta_al_trimmed; alignment length = 302] Allma1 IAVTGLGLVTPLGVGVWKALLA-GQSGITVAGVVPRKTSLFIQHALKAAKEALDDASGIGGVDDFSATPFAVPKALVNLAAGWVSLTHGFQGPSHCVATACAAGANAIGDAARMIQYGDANVMVAGAAESTINAISLAGFARAKALAASRPFDQKRAGFVMGEGAGVVVLEDLEHARARGAVYAVLAGYGTSCDAHHITAPPDDGRGAARAMEQALRGIVAHINTHATSTEQGDVAELRAIRTVFIQIAATKSATGHLLGAAGAVEAIWAVLALVPPTLNLAVMSNSFGFGGTN-ASLVFAH Ashgo11 VVVTGIGCYTPLGPSLWKELLR-GTSGLPLSRLISRRTSRAAQLAMVTAEEALRHAAGLPSMEDISQAPFFIPKMLNNMAAGNVAIKFQLRGASNCPSTACASGNNAIGDAYNFIRLGYSDVIVAGASELSVHPLALAGFVKAKSIGISRPFDARRDGFVLGEGCGLLVLESLEHARHRGAIIAEVVGYGVCSDAHHITSPSEGGDGARRAMHMALQDAVGYVNAHATSTPLGDRAEARAIQAVFTLVSSNKGHMGHLLGAAGAVEAVFTVQSLVPHTLNLYAMNNSFGFGGIN-SSLLFKK Aspfu1 ------MALLIMALWVWKRLLD-GHCGIQIAAVVPRKMARFAQYAMAASEEALEDASGIGNFDEIYDTPLFVPKLLINLGAGHLSMRYGFMGPNHAVTTACTTGAHSIGDAARFITCGDADVMLAGGAESCIHPLAIGGFARARSLKASRPFDADRKGFVVGEGAAMLVLEELEHAKARGAIYAELKGYGCSGDAHHMTAPKENGEGAWMAMKKALKNAVDYVNAHATSTVVGDAAENAAIKSLLINVSSTKGAVGHLLGGAGALESLFTVLAIMPPTINLVALTNSFGFGGTN-SSLCFSK Aurde31 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 VVVTGLGLVTPLGCDVWSRLLS-GDSGIQVAALVPKKMPPFILYARYAASRALKDAARMGCIDDTVNLPYLVPRLLINMASGHISIEHKLKGPNHSVSTACATGAHAIGDAMRFIQYGDADVMVAGGTESAISPISMAGFAKAKSLEASRPFDRDRDGFVMGEGAGVVVLEEMDHAVKRGAIYAELSGYGLSGDAHHMTAPPENAHGAARAMRRSLQIAIDYVNAHATSTEIGDLAETRAIRDVLVAVSSTKGAIGHLLGAAGSVEAIFTILSLIPPTLNLAALTNSFGFGGTN-ASLCFKK Botbo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 VVVTGLGAITPLGVGIWSRLLA-GNCGITIAGLVPSRMAKFTQYAIAATEMALQDASGIGGLDELYTAPFFVPKLLINLAAGHISMKYGFEGPNHAVTTACTTGAHAIGDASRFIAFGDADVMIAGGSESCIHPLAFAGFAKARSLSSSRPFDRDRCGFVIAEGAGVVVLEELEHAKARGAIYAEIRGYGCSGDAHHITAPKEDGAGAFLAMKRALKNAVDYINAHATSTPLGDAAENAAITRLMIAVSSTKGAIGHLLGAAGAVEAIFSILAVLPPTLNLVSVSNSFGFGGTN-ASLVFSK Caeel -----------------------------------------------------------------------------------------MRGGVESTSTACATGLHCIGNSFRSIRYGDSRRALAGAVECALNPIALAGFDRMRAL-ISRPFDKKRAGFVMSEGVGLVFMERLEDAQARGAILAEVVGYGISSDCYHISTPDPSAIGAVLSMNRAIGNAIGYVNAHATSTPNGDSVEAEAVRQVFIAVSSVKGHIGHLLGAAGSVEAIATIFAMLPANRNLISICNSFGFGATN-ASLILKQ Canalb1 VVVTGMGMVSPLGVGLWKQLIA-NKSGLKVIGKVPRRMATFSHYALASTHEALQDASGIGSFEDIYNNPLFIPKLLNNMAAGNISIKYQTKGPLHSVSTACATGLQAIGDGFNFLKMGYGQVMICGGTESSIHPLALAGFARARSVKASRPFDKSRNGFVLSEGCGILVLETLSHALERGVIYGEILGYGVSGDAYHITAPHEDGTGAYNAMNQAIERSIDYVNAHATSTVIGDRAENNAMMRLFTKVSSTKSSIGHLLGAAGAVESIFTLNAIIPATLNLYAVCNSFGFGGVN-SSLCFAK Cangl VVVTGLGCVTPLGKSVWHRLLQRDSNGLKWRGIFPRRMSRFIKLATIASYEALVSSSGIGSIEDIYETPYFVPRILTNMAAGNIAIKFNLRGPTHSVSTACATGNNAIGDGYNMIKLGMQDICLAGASEASVHPLSLAGFLRAKSLGISRPFDEERNGFVLGEGAGIVVLESLESAERRGAILAEIVGYGLSCDAHHITSPPNDGEGASRAIKMALDLSIEYVNAHATSTKLGDNTECCAIQNTLLYISSNKGSIGHLLGAAGAAESIFTILSLIPHTYNLYALCNSFGFGGVN-TSLLFRR Capow VVVTGLGLVTPLGVGVWKRLVA-GDCAVSIAAQVPKRMPDFIQFAMAAASQALDDACGMVSMDDMATAPFFVPRILVNMASGHVSIRHGLRGVNHSVSTACATGAHAIGDAFRFIRNGDAEVMVAGGTEACITPLSVAGFCKVKALLASRPFDERRDGFVIGEGSGVLVLEEYEHAKRRGAIYAEIRGYGLSGDAFHMTAPSEDGRGAIHCMESAIRQAVDYVNAHATSTPLGDAVENRAIKTVFLAISSTKGAIGHLLGAAGAVEAIFSVLAIVPPTANLAALSNSFGFGGTN-ASLCFGS Catan2 VAITGIGLVTPLGTSTWHHLLA-GHSGIHIAGLVPRKSSRFIHHALVAAHEALQDASGIGSIDDFAACPFAVPRALVNMAAGWTTLTFGLWGPNLAPASACAAGAHAIADAARLIRCGEASVMLAGASESTINPVSLGGFARAKALRASRPFDSSRAGFVMGEGAGVLVLEDLDHALARGAIYGLVAGYGASADAYHVTSPEPTGRGAKRAMQVALQGLVGYVNAHATSTEQGDAVELGAIREVLVMVSSTKGAMGHLLGAAGAVEAGVAVLSMVPGTLNLAVLSNSFGFGGTN-ASLLFTK Cioin VVVTGIGIVSPLGCGVWSRLLK-GCCGIKVGAGVPREVSKATAFAAAAAEEALNDAMGMVDLDAVSSTPYFIPRILLNMGAGHISMKYKLKGPNHSVSTACTTGAHAIGDAARFIIHNDADVMVAGGAESCLNVLAFSGFSKARALVASRPFHPDRDGFVMGEGAAVLVLEEEQHAVQRGAIYASLLGYGLSADASHITAPPEDGNGAYRCMKSAVQDAVTYINAHATSTPLGDAAENRAIKRLFPAVSSTKGAVAHMLGAAGAIEAAFTVLSCLPPTLNLIALTNSFGFGGTN-ASLCFSS CocheC53 VVVTGLGLVTPLGLGVWKRLID-GHCGIRIAGLVPRRMARFAQYAMVAAEEALQDASGIGSLDDVYDTPLFVPRLLINLAAGHISMRYSFKGPNHAATTACTTGAHSIGDASRLIQFGDADVMIAGGSESCIHPLAISGFARARSLESSRPFDKQRDGFVIGEGAGVVV---LEHAQRRNAIYAEIAGYGLSSDAYHMTAPREDGQGPRLAMKNALRHAVDYINAHATSTPLGDAAENRAIKALLINISSTKGAVGHLLGAAGSVEAIFTVLGMLPPTLNLVALSNSFGFGGTN-ASLCFRK Coere1 INKQGEYLITPVGVGVWHNIIE-AKSGIQVAGIVPARLALFAQYALCAAHQALADATGIGSLEDIVDNPMFVPRTLCNMAAGNISIRYGFYGPNHAVSTACTTGAHSVGDAMRFIQFGDADVMVAGAAEAPLLPLAIGGFSRIKALAASRPFDKRRAGFVIGEGAGALILEELGHAQRRGAIYAELRGYGLSGDGHHITAPPPDGAGARRAMLHAIRSAISYVNAHATSTPLGDKIENQAIKAALLPVSSTKSATGHLLGAAGAIEAVFAVLAVAPPTLNLTSITNSFGFGGTN-ASLVFTK Conco1 VVITGLGLVTPLGNTVWAKLLG-SQHGIRIGGVVDRLMPKFIKYGVSAAHQALTDSSGIGSLMDTVNTPFFVPRILVNMAAGHITIKYGFRGPNHSVSTACTTGAHSIGDAYRFILHGDAKVMVAGGSESSLNPLSYAGFGRAKSLQASRPFDSKRDGFVIGEGAGAIVLEELEHAKQRGAIYAEIKGYGLSGDAHHITSPPDDARGAYRAMQRALETAIGYINAHATSTPKGDALERLAIERLFLAVSSSKGAIGHLLGAAGAVESIYTILALLPPTLNLYALSNSFGFGGTN-ASLCFGK Conpu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 VVVTGLGAVSPLGVGAWKRLLA-GEAGLTVAGLVPRRMSKFAQYAIAAAEMALVDASGIGNLDELYTTPLFVPKILINLAAGHVSMKYGFQGPNHSATTACTTGAHSIGDASRFIAYGDADVMVAGGSESCIHPLTFAGFGRSRSLASCRPFDRDRDGFVVAEGAAVLILEELEHAKARGAILAEVAGYGCSGDAHHMTAPREDGSGALLAMKRALKNAVNYINAHATSTPIGDAAEASAIRTLMVTVSSTKGAVGHLLGAAGAIEALFSVLAIVPPTLNLVSMSNSFGFGGTN-ASLVFSR Debha1 IVVTGLGLVTPLGVGVWANLIA-NKSGLKVVGKVPRRFALFSQYGLVATEEALKDASGIGSFEDVYENPLFVPKILTNMAAGNISIKYGLKGPNHSVSTACATGLHSIGDAYNFIKNGYAKVMVAGGTEATIHPLALAGFARAKSVKASRPFDKDRSGFVLSEGCGMMILEELDHALNRGLIYGEIKGYGLSGDANHITAPREDGDGAYRAMTMALKFAVDYVNAHATSTVIGDRSENNAIAELFLSVSSTKSSIGHLLGAAGAVELIFTVKTIMPPSLNLYSLCNSFGFGGTN-SSLCLSK Dekbr2 VVITGMGLVTPLGVGVWSKLIS-AKSGLKVVGAVPRRIPPFIQYAIVAAREALHDASGIGSFQDTYENPLMVPRILTNMAAGNVSIYFNLKGPNHAVSTACATGAHSIGDAALMIKEGYADAMVAGATEASVHPLALAGFARAKSVAASRPFDKDRKGFILGEGAGVVLLESLEHALERGAIYGEVCGYGMSGDATHITSPPANGDGAFRAMQCAIKRAIGYINAHATSTVSGDRAENYALKRLFLAVSSTKGAIGHLLGASGAVEAIFTMLALLPPTLNCYALTNSFGFGGTN-ASLCLSR Dicdi VVVTGMGIVSPLGVGIWDKLIN-GESGIKVVARVPLASSDFIKYAIVATDEAIKDSSGTGSMEEIISAAYFIPKILINEASGIISILHKAKGPNMSIVSACATGSHCIGESFRKIKYGEVDAMICGGTEASINSVSMIGFSRMKALSSSRPFDEGRDGFVMGEGSGILILEEYEHALKRGAIYCEITGYGSTGDAHHISAPNSDGNGPLRSMNLALLESIDYINAHATSTPLGDGIECTAVKNFYIIMSSNKGSIGHLLGAAGSVESIFSILSLIPPTLNLNVLKNSFGFGGTN-CSLIFSK Dmel VVVTGSGAVTPLGNNGWRRILA-GESAIQVAAQIPKLMSPATQLAVLAAEEALSTGMGMFDLAEVYGAPFFVPRLLPSMACGHISMRHGLRGPNHSVSTACATGAHALGDAMRFIRSGDADLMLAGSGEACIDPLSIAGFCRLRALVASRPFDKSRDGFVMGEGAAVLLLEELEHARARGAILAEILGYGLSGDAYHITSPSDDGAGATLAMKRAIQDAVTYVNAHATSTPTGDRIESHAIGRVFVRVSSTKGAHGHLLGSSGNLEALFVVLACLPPSINIVALKNSFGFGGTN-ASLCIAS Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 VVVTGLGAITPLGVGVWTRLLS-GECGITVSGLVPRRMSKFTQYAIAASDMALKDASGIGNLDEIYDTPLFVPKILINMAAGHIAMKYGFQGPNHAATTACTTGAHSIGDASRFISMGDADIMVAGGSESCIHPLTFAGFGRARSLASCRPFDADRNGFVVSEGAAVLILEELEHAKARGAIYAEIKGYGCSGDAHHMTAPREDGRGAFLAMKKALKNAVDYINAHATATNVGDVAETSAIRRLMITVSSTKGAVGHLLGAAGAIEALFSVLAIVPATLNLVAVSNSFGFGGTN-SSLVFSK Galma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 VAVTGLGLVTPLATGVWKKLIN-SESGITIAGVIKSRMALFSHYAICAAKQALNDASGIGSLEDVVSNPMFVPRILINMAAGHLTMKYGFRGPNHAVSTACTTGAHSIGDASRFIQFGDADVMVAGGSEACVLPLAMSGFAKAKSLKASRPFDKDRDGFVVGEGAGMVVLEEYNHAINRGAIYAELSGYGLSGDAHHITAPPENGIGAELAMRRALSQAIDYINAHATSTQLGDIAENRAIKSIFLAISSTKGSIGHLLGAAGAVEAIFTILAILPPTLNLAALTNSFGFGGTN-ACLCFVK Hisca1 VVVTGLGAVSPLGIGVWTRLLD-GHCGVQIAALVP---------------------------------PLFVPKLLINLGAGHISMKYGFAGPNHAATTACTTGAHSIGDASRFIACGDADVMIAGGAESCIHPLVLGGFSRCRSLKASRPFDRDREGFIVGEGAAVVVLEELEHAKSRGAIYAELKGYGCSGDAYHMTAPKESGEGALLAMKRALRNAVDYINAHGTSTVIGDAAENFAIKTLLINVSSTKGAIGHLLGGAGAIEAVFSILAILPPTINLVAMTNSFGFGGTN-STLCFAR Klula1 VVVTGLGAYTPLGSTVWAGLLA-AKQSLKVKKLVPRRMTPAHQIVLEKTKEALLQATGMPSMPDLESTPFLIPRVLPNMAMGNVMIKYGIQGPSSCPSTACATGNSSIIEGFNSIQLGLADVMICGSYEFSIDPISIAGFYRSKTI-QTRPFDVERDGFIMGEGCGILTLESLESALKRGSILAEISGVGLSNDGYHITSPLPDGSGGKLAMQNALKRAVGYINAHATSTQLGDVAESTAITELFPYVSSNKGHIGHLLGASGSVESIFTVLSLFPHTLNLYALTNSFGFGGVN-TSILFRK Lacbi2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele VVVTGLGCVSPLGLTAWKNLIA-GECGIRIAGVVKRSANRTTGFAMSAAVEATNQASSLAGFMETVATPFFVPRILDNMAAGAIAMRFNLLGPNHSCGTACTTGAHSIGDGFNLIRLGMADVMLCGSAEACLHPLALSGFCQAKALQSSRPFDESRSGFVMSEGAAVLILEEMEHALRRGAVLAEVVGYGLSADAHHITAPHPDGRGALNAMRGALKETVSYINAHATSTSLGDLAEGTAIQHIFLGWWSSGIYPDCLRGRSGV----------DPPILEEICLCNHLRLTQPNDRETAFER Monbr VVVTGLGLITPLGCGPYEHLLH-KASGVHIAAEVPRALPPNIQFALAAAEQALCDATGISGVHDLLSNPYLIPNALVNMSAGLVSIHHNLQGPNLSASTACATGAHSIGDAFRMIKYDDADIMVCGGAEACIHPLIMSGFARAKALRASRPFDQARAGFVMGEGAAVLILEEEAHARARNAIYAQVLGYGASGDAHHITAPHPSGRGAIGCMQAALREAVQYVNAHATSTPIGDEIEGRAIAQVCVAVSSTKGATGHLLGAAGALEAAFAILALAPPTLNLVALSNSFGFGGTN-VSLAFGK Morel2 VVVTGLGLVTPLGIGVWSKLIA-GECGVQVGAIVKKRMAVFTQYAIAAARMAIKDASGIGSLDDMATTPMFVPKILINMAAGHLTMKYGFKGPNHAVSTACTTGAHSLGDAMRFIQYGDADVMVAGGSEACIHPLAVAGFAKAKSLEASRPFDKNRDGFVIGEGAGVVVLEEYEHAKKRGAIYAELRGYGLSGDAHHMTAPPENGTGAAMAMRRALKAAIGYVNAHATSTHQGDIAENRAIKSVFIAVSSTKGAVGHLLGAAGAVEAIFAILAVLPPTLNLAAITNSFGFGGTN-ASLCFAK Mucci2 VVVTGLGLVSPLGVGVWKNLLD-SQCGIRIAAEVPRTMAKFSHYAIAAARQAINDASGMGSLEDIVDTPMFVPRILINMAAGHLTMKYGFQGPNHAVSTACTTGAHAIGDAMRFIQYGDADVMVAGGTEASVHPLAIAGFARAKSLEASRPFDKDRSGFVMGEGSGVVVLEEYEHAKKRGAIYAELKGYGLSGDAHHMTSPPEHGQGAVRSMRRALQVAIDYVNAHATSTPAGDVAENRAIKTVFINVSSTKGATGHLLGAAGAVEAIFSILSVIPPTLNLAAITNSFGFGGTN-ATLCFAK Mydma VVCTGIGIVSPLGCGSWEKLVN-GHIGVKVAAFVPKFLSQSMLYALSAADFALEDSSGMVDLEAIANTPYFVPRILINLAAGHISIKYGFQGPNHAVSTACTTGAHSIGDSMRLIKNGDADVMVCGGTDAAIVPVAVAGFSRARALTSSRPFDSKRDGFVIGEGAAILVLEEYQHAIKRNALYGEVIGYGMSGDGYHMTAPREDGIGAYLCMKAALRDAIQYVNAHATSTPIGDAVENRAIKKCFIKISSFKGAIGHLLGAAGAVETAFTLLAIIPPTMNLIALKNSFGFGGTN-ASLCLGE Neucr2 VVVTGLGAITPLAVGIWRRLLD-SHSGITVGGLVPRRMSLFAQYSVAATEMALQDASGIGNLDDFYNTPLFVPKILINLGAGHIAMRYGFRGPNHSATTACTTGAHSIGDASRFIAFGDADVMVAGGSESCIHPLTFAGFGRSRSLSACRPFDKDRAGFVVSEGAAVLILEELEHAKRRGAILAELTGYGCSGDAHHMTAPRDDGSGAFLSMKRALKNAVDYINAHATGTAVGDAAEAIAIRSLMITVSSTKGAIGHLLGAAGAIESVFSILAIIPPTLNLVAMSNSFGFGGTN-ASLVFSK Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 VVVTGLGAVTPLGVGIWKRLLD-GHCGVQVAAVVPRKMAQFAQYAMAATEEALQDASGIGNFDEIYNTPLFVPKLLINLGAGHISMKYGFMGPSHSATTACTTGAHSIGDAARFIACGDANVMVAGGAESCIHPLAIGGFARARSLKASRPFDADRAGFVVGEGAAVMVLEELEHALSRGAIYAELKGYGCSSDAHHMTSPKENGEGAFMAMKKALKQAVDYVNAHATSTIVGDAAENAAIKALLVNVSSTKGALGHLLGGAGAIEALISVLAIMPPTINLVALTNSFGFGGTN-SSLCFAN Phybl2 VVVTGLGLVTPLGVGVWQNLLK-SQCGIRIGACVPRVMAKFTQFAIAAARQALEDASGMGSLEDIVATPMFVPRILINMAAGHLTMKYGFQGPNHAVSTACTTGAHSIGDAMRFIQFDDADVMVAGGAEASIHPLAIAGFARAKSLESSRPFDSDRAGFVMGEGAGVVVLEELEHAKKRGAIYCELRGYGLSGDAHHMTAPPSDGRGAEKSMKRALARAIDYVNAHATSTAVGDAAENNAIKRVFVAISSTKGATGHLLGAAGSVEAIFTILSILPPTLNLAALTNSFGFGGTN-ATLCFSK Picst3 VVVTGLGAITPLGVGVWRNLLA-GKSGLKVIGKVPRRLALFTQYGMVASKEALEDASGIGSFHDVYENPLFIPKLLTNMAAGNILIKYGLQGPLHAVSTACATGLHAIGDAYNFIKNDYADVMICGGTESSIHPLALAGFARARSVAASRPFDGSRNGFVLSEGCGIVILERLDHALNRGVIYAEIKGYGLSGDAHHITAPMETGEGAYLSMKMAVDRSVGYVNAHATSTVIGDRAENNAILRLFVAVSSTKSSIGHLLGAAGAVESIFTIKAVIPPTLNLYALCNSFGFGGVN-STLCFGK Plicr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo VVVTGLGMLTPFGRGVWSRLVD-SSCAIKVAAQIPSGCSDFIKYAIVASQDALQDSSGIGALGEVTSAAYFVPRILINEASGIVSILNKIKGPNLSVVSACATGAHAIGESFRKIKYGEVDVMLCGGTEASINALSIIGFSRMKALQASRPFDEGRDGFVMGEGAGILVLEELEHALARSAIYCEVLGYGASGDAHHISAPEPSGEGARRSMSQAIREAIDYVNAHSTSTPLGDAIECKAVIDLFLAMTSNKSAIGHLLGAAGSVESIFSILALIPPNLNLIVLKNSFGFGGTN-ATLLFKK Pucgr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ------------------------------------------------------------------------------MAAGHLTMKYGFQGPNHAVSTACTTGAHALGDAMRFIQYNDADVMIAGGTEASIHPLAIAGFARAKSLEASRPFDRDRSGFVMGEGAGVVVLEEYEHAKKRGAIYAELKGYGLSGDAHHMTTPPANGEGAALSMRRALRAAVDYVNAHATGTPVGDVAENRAIKSIFVSVSSTKGATGHLLGAAGSVEAIFTILSVLPPTLNLSAMTNSFGFGGTN-ATLCFTK Rhoto1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 VVVTGVGTVNPLGNSVFENLIS-GKCGIKVAARITS-IPKFIQYSLHSTEEAVKMATGLGNLEYICQSAYTIPYILNNAPAGFISKQYQCHAFSHSVSTACTTGLHSIIDAFRYIQSRDADIVIAGATE-----------------RASRPFDADRCGFVVGEGSGTLVIESLEHALSRGAILAEICGYGLSSDAYHMTSPFPEGEWIKYSMRNALRGIVDYINAHATSTVAGDIEEAKAIESLFILVSSCKGSIGHLLGAAGAVELIFTIMSMAPPNLNLYALSNSFGFYGTN-ASIVLKK Sacce1 VVITGLGCVTPLGRSLWGNLLS-SKNGLLREKSIPRRTSSFIKLALRTTYEALHNASGIGSIQDIYQTPYFVPKILTNMAAGNVSIKFNLRGLSHSVSTACATGNNSIGDAFNFIRLGMQDICVAGASETSLHPLSLAGFIRAKSIGISRPFDTQRSGFVLGEGCGMIVMESLEHAQKRNAIISELVGYGLSSDACHITSPPADGNGAKRAIEMALKMAVDYVNAHATSTLLGDKAECLAVASALLYISSNKGAIGHLLGARGAVESIFTICSLMPHTLNLYALCNSFGFGGVN-TSLLFKK Salro VVVTGLGAVSPLSATAWQRVVR-GDCAIKLAATVPRTLPDSILYALSAADEAIADATGISGLQDLIAAPYLIPNSLVNMAAGLISIDYGLRGPNHAVSTACATGAHAIGDAYRFIKYGDADVMVCGGADACIMPVVVAGFARAKALESSRPFDRRRSGFVIGEGAALFVLEELEHARARGAIYAEVRGYGLSGDAHHVTAPHESGDGAYRAMRAALDSALDHINAHATSTPLGDGIECRAIKALLPTITATKGATGHLLGAAGSLEAMFAVMSIVPPTLNLFALSNSFGFGGTN-VSLLFSK Schco3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 VVITGLGAVTPLGNGVWRNLIQ-GKSGIKVAGVIPREVATFTQLALTSAAEALKDATGIGNLDDALNEPRVISKILINMPAGYISQRYGFTALNHTTTTACAAGCHAIGDAFNFIKLGHADVIIAGGSESCINPLTVAGFSKARSLAASRPFDANRDGFVIGEGSAALVLEELEHAKNRNAIYAEIVGYGLASDSYHITAPNPNGDAAYYAMKRSLKQALDYINAHATSTKLGDVAESIAITRLLFPVSSSKGSIGHLLGAAGAIESVYTVLTVLPPTLNFVALSNSFGFGGTN-ASLCFKK Sorma VVVTGLGAITPLAVGVWRRLLD-SHSGITVAGLVPRRMSLFAQYSVAATEMALQDASGIGNLDDFYSTPLFVPKILINLGAGHVAMRYGFRGPNHSATTACTTGAHSIGDASRFIAFGDADVMVAGGSESCIHPLTFAGFGRSRSLSACRPFDKDRAGFVVSEGAAVLILEELEHAKRRGAILAELKGYGCSGDAHHMTAPRDDGSGAFLSMKRALKNAVDYINAHATGTAVGDAAEAIAIQSLMITVSSTKGAIGHLLGAAGAIESVFSVLAIIPPTLNLVTMSNSFGFGGTN-ASLVFSK Sphar VVVTGLGLITPLAVGVWERLLA-GQSGVNIGAIVPRRIPPFAVYALAAADEALKDAVGIVGLSEIAETPFFVPRILVNIAAGHVSMRYGLKGPNHAASTACATGAHSIGDAFFHIKNGNADVMVAGGVESCVSAVSVAGFARIKALQASRPFSAGRDGFVIGEGAGIMVLEEREHAIQRGAIYAEMRGYGSSGDAHHLTAPSPEATGAKTSMELAIRMSFDYINAHATSTPMGDTLEAMAISSVFISVSSTKGATGHLLGAAGAVESIFAVLSIIPQTLNLAVLSNSFGFGGTN-ASLCFAE Spipu1 VVVTGLGLVTPLGTGVWSGLLA-GRSGIQVAALVPRNMAPFMHYALSAAQQAITDSSGIGCLDEMESTPYFVPKILINLAAGHISMRYGLQGPNHAASTACTTGAHSIGDAMRFIQFGDADVMVAGGSEASVSPLAMAGFAKARALASSRPFDRDRDGFVIGEGAGCMVLEEYEHAKARGAIYAELRGYGLSSDAHHITAPPDDGRGAARSMQRALEIGIDYINAHATSTGLGDLSETRAIKTVFVAVSSTKGAIGHLLGAAGAVEAIFTVLAILPPTLNLAALTNSFGFGGTN-ASLLFAK Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr SAATELATDRPRRVSSWQGLAS-GASATSVAALTPARSSRFIHLAAAAAAEALEDASGMGSMADIHDGPFFVPRILVNLAAGTVSIAHGLQGPNHAVATACATGAHSIGDAANFIALGYADVMVAGSSEAALDPLALTGFARAKALVASRPFDQLRDGFVMGEGAGVLVLEEREHAIARGAIYAELQGYGLTGDAHHTTAPAPDGRGALRAMRMALRRALDYINAHATSTSLGDAVEYSAIHKLLLLVSSSKGAIGHLLGASGSVEALITVLALAPVNTNLYALSNSFGFGGTN-VSLCFAS Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 VVVTGLGAITPLGLGIWTRLIA-GESGITVAGVVPRRMSLFTQYAIAASDMALEDASGIGNLEEMYETPLFVPKLLINMAAGHIAMRHGFQGPNHAATTACTTGAHSIGDAARFIAHGDADVMVAGGAESCIHPLTFAGFGRARSLSACRPFDADRDGFVIAEGAAVCVLEELEHAKARGAIYAEVRGYGCSGDAHHMTAPREDGHGAYMAMKRALKSAVDYVNAHATSTQVGDSAEAAAIKRIMVTVSGTKGAIGHLLGAAGAIEALFCILAIVPATLNLVALSNSFGFGGTN-STLVFSR Umbra1 VVVTGLGLVTPLGTGVWENIIN-SKCGINIGAAVKRTTALFTRYAISSAKQALQDASGMGSLDDLYTTPMFVPKILINMAAGHLTMKFGFKGPNHAASTACTTGAHSIGDAMRFIQFNDADVMIAGGSEACIHPLAIAGFCKAKSLESSRPFDKDRSGFVIGEGSGVVVLEEYEHAKRRGAIYAEIKGYGLSGDAHHMTAPPENGQGAALAMKRALGHAIDYVNAHATSTPQGDVAENRAIKSIFISVSSTKGATGHLLGAAGAVEAIFTILALLPPTLNLAALTNSFGFGGTN-ASLCFAK Ustma22 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 VVVTGLGCVTPLGNTVWTNLLN-SKSGIIHANSIPRRLSRFSQFALKASHEALQNASGIASIEDVYDTPLFVPKILTNMAAGNVSIKFQLKGPSHSVSTACATGNNAIGDAYNLIRLGMQDACLAGASEACVHPLSLAGFIRAKSIGVSRPFDRNRSGFVLGEGAGIVVLESLDHARRRGAILGEICGYGLSSDAYHITSPSPGGHGAMRSMRMAVGNTIQYVNAHATSTLLGDRAECSAILNLLVYVSSNKGSMGHLLGAAGAVESIFTILSIIPHTLNLYALCNSFGFGGVN-TSLLFQK [Cluster3568.fasta_al_trimmed; alignment length = 112] Allma1 VTILDSSHNPPNAAHMALLRTAAVLILLAVQNADKLDLAHRLAMMVAIDTTTDHALFKDKAADIHLRWVLGEDTLLRIFDPKYYVAATMSTFLWARRVSSTSVRDAVVARYI Ashgo11 LLVLDSSFNPPHFGHCELIERAHVLLLLSVNNADKATFDKRLYMMLAE-LLTTHARFIEKTGAIPITYLMGFDTLIRFFDPRYYLIEALTELFCLTRLSSTKVRNLIILDYI Aspfu1 LYVLDSSFNPPTLAHLRIASSARLLLLLATQNADKANFEDRLAMMFAQDLVTKKPYFVDKAAEIEQVHLTGYDTLIRIFNPKYY--QRLHRLRVTMRVSSTKAREAIVREYI Aurde31 VLVLDASFNPPTKAHLALARTPATLLLLSVTNADKATPEQRLEMMLANELAIDAPTFVGKAHALQLSFAMGTDTLVRLLNSKYYMHSALARVLCAHRVSSSEVRASIIAQYI Batde5 MLVLDSSFNPPTKAHLNLMVHTCCLMLLSTVNMDKTPVLDRLEMMLIESILTNQASFIDKLAAITVYFIMGCDTLKRFFDTKYYPDQTLGRIISASRISSSHVRDLFIFEYI Botbo1 VSVLDSSFNPPTRAHLALARTAAHLLLFSVRNVDKASPVQRLQMMLARDLVIDEPTFVGKATKL-LTFIVGYDTLTRLFAPQYYMRTAVSSVVCARRISSTAVRNGVIVEFV Botci1 --LLTNWYYPHSAYHYKKEKLDAESLEIDSNSEPESSLPQ-----SSEPLLTSLPYFHDKSAAITHIHCTGYDTLIRVLNPKYYDLSPLHKLRVTYRISSTKVRSMVVGKWI Caeel ---------------------------------------------------------------------------------------------------------------- Canalb1 VCILDSSFNPPHLGHYALIEESVVLLLLSVKNADKESFDKRLDMMMANDLLTNHAKFVDKSLSVKLTFLVGFDTLIRIFDPKYYLSNSLTDLFCLTRISSSSIRKQIIANYI Cangl VLVLDSSYNPPHLAHFTLVKNAHVLLLLATNNADKATFDKRMAMMFAD--LTTHGKFVDKLVDIVITFLVGFDTLIRIFNPVYYVAEALVEFCCLRRISSSMVRDVVIVEYI Capow ---------------------------------------------------------------------------------------------------------------- Catan2 ILILDSSHNPPTRAHAHLVSTGAVLLLLATRNADKSAIAHRTKLMLATHLTTGCALFADKANAFRLDWITGNDTLIRIMHPKYYRQVIVSRLLVAPRVSSSLARDLRVAEYI Cioin ---------------------------------------------------------------------------------------------------------------- CocheC53 LYILDSSFNPPSLAHFTLATSARLLLLFSTHNADKASFVQRIALMLAEDLLTKEPYYSDKSAAIKHVHLVGYDTLIRFCNPKYYPLSALHKLRVTQRISSTRVRNAAVAAWI Coere1 VGVMDSSFNPPHYCHGAYMECLAYLLLLGSENADKSGLEQRMRMVLATTVMTNTPRFVDKCRAVS-YFAMGWDTLIRFFDPKYYYPQELGRIAYSRRISSSSVRLAVILEFV Conco1 TIILDSSFNPPTRAHAALITQSQVNLCFCLNNMDKNIFNYRLELMFKKDLITNQGRFFDKAEIFSFYFIMGLDTLVRFVDLKYYLQTKLCQIVLGWRVSSTSIRNSIVIHYI Conpu1 ISVVDSSFNPPTLAHLALANIPAKLLLLSVRNADKASQVQRLEMMMAKELIIDEPTFAGKSTALQMTFTMGYDTLIRLISPRFYMHQALCNIVCARRYSSTAVRTKVIAQYI Copci ---------------------------------------------------------------------------------------------------------------- Croqu1 ---------------------------------------------------------------------------------------------------------------- CryneH991 LAILDSSFNPPTLAHQAIISSSARLLLYTPKNAAKATPLQRLEMMLSSSLLIHAPTFAAKASILDLSFLVGMDTLVRIFDPNYYMQTKLANLVCARRVSSTLVRECVMSLYI Crypa2 LVVLDSSFNPPTIAHMRMATTARLLLLLAVNNADKASFEQRLLMMFAGDILTTRPYFHDKSSAIEQIFLAGFDTLIRIFNPKYYMQACLARLRITMRLSSTEARAAVVAGLI Debha1 ICVLDSSFNPPHLGHYSLVRESIVLLLLSVNNADKASFDHRIEMMLADHILTNHAKFVDKSEAIRLSFLVGYDTLIRILDPKYYLETALSDLFCLTRISSSSIRSNIIKNYI Dekbr2 VLVLDSSFNPPHFGHATLVKKSSVLLLLSSKNADKGNYSLRLDMILASHILTTKSLFTEKISAIKFTFLLGFDTLVRSFDPKYYISSALSSFFILSRISSSEIRAMIIIGYI Dicdi ---------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------- Fomme1 ---------------------------------------------------------------------------------------------------------------- Fusgr1 LVVLDSSFNPPTLAHANMARTARLMLLLSVNNADKASFPIRLSMMMG---VTTMPFFHDKAKAITQTFLAGFDTIVRIFNPKYYIRSALCKVRVTTRVSSSRVRDVVVRGWI Galma1 ISVLDSSFNPPTLAHLALANSRAKLLLLSVKNADKATYQQRLEMMLASDVIIDEPTFVGKSATLELTFIVGLDTLERLFSPRYYMMTSLSRIISAQRYSSTTVRRSRVAEYI Ganpr1 LVVLDSSFNPPTLAHQRLVSLASYLLLLATSNMDKASLADRLVMMTAERLCTSAGRFLEKAQVIRAHFLLGWDTVVRFFDEKYYMTQGISTLIIADRMSSTRARELLVAAWV Gloin1 --------------------------------------------MLASHIVVTHPRFIDKAHGISLYFIMGYDTVIRLFNPQYYMREELNYIICANRISSTRVRDIVIVEFV Hisca1 LYVLDSSFNPPTRAHLSIAKSARLLLLLATQNADKASCEDRLVMMFAEDIITKLPYFIDKAAAIEQILLTGYDTLERIFDCKYY--QPLHRLRVTFRMSSTKARNAAICDWV Klula1 ---------------------------------------------------------------------------------------------------------------- Lacbi2 ISILDSSFNPPTVAHLALANSPAKLLLLSVKNADKATYLQRLEMMLAKDIITDEPTFVGKSKNLQLTFLLGLDTLQRLFSPKYYMIDVMSRVVCARRYSSSAVRNSIVADYI Lenti61 ISVLDSSFNPPTLAHLALASILARLLLLSVRNADKATYEQRMEMMLTQDLIIDEPTFVGKSALLKLTFLMGTDTIVRFFAARYYMQTALSRIICARRYSSSEVREKIVAAYV Malgl1 IAVLDSSFNPPTRAHAALASLPAHLLIFSVRNADKASPLERLEMMLAYELLADEPLVFSKSSLVQLCWLVGSDTITRVFHPRYYFAACCSAMLCAERHSSTAVRQFLLAEYL Mellp23 ---------------------------------------------------------------------------------------------------------------- Mnele ---------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------- Morel2 IAVLDSSFNPPTKAHYQLLKAAAVLLLLATNNVDKAGAVERLEMMVA---LTIHARFMDKAQPIQLSWIMGHDTMTRLFDPKYYADMA-CDVICSSRMSSTVVRNAIVRQLI Mucci2 LLVLDSSFNPPTKAHAKLLQTSGSLLLFSTNNVDKASVLQRAQMMIALQYFTPHGRFMDKAKYIELYFIVGYDTMIRLLDPKYYVKDALCHLICADRFSSTLAR---IPTLL Mydma ---------------------------------------------------------------------------------------------------------------- Neucr2 LIVLDSSFNPPTLAHLRMATSARLLLLLAVVNADKAAFDQRLAMMFAHDVLTSKPYFHEKSRVIEQVILVGFDTLIRIFNPKYYIQQALAKLRVTLRVSSTYARKAAVGKWI Orpsp11 IIILDSSFNPPTLAHIKLITETTFILLITNNNVDKANLSQRLLMMVSDIF------------------------VIKIANEKY----------------------------- Pench1 LYVLDSSFNPPTRAHLRIVTTARVLLLLATQNADKASFEDRLVMMLARDLVTKKPYFIDKAAAIEQVHLTGYDTLIRIFNSKYY--KPLHRLRVTMRVSSTRAREALVRRFV Phybl2 ILVLDSSFNPPTLAHRALLTESASIVLFSTRNVDKASVLQRAQMMMARQFLTPHGRFIDKSIHIKLYFIMGFDTITRFLDPVYYT--ALSHLICADR--------------- Picst3 ICVLDSSFNPPHLGHYALIKESSILLLLSVKNADKESFENRLEMMMANDLLTNHAKFVDKSVSIKLTFLVGFDTLTRILNPNYYLSTTLTDLFCLTRISSSAIRASIVRDFI Plicr1 VSVLDSSFNPPTLAHLALANSSAKLLLLSVRNVDKATYLQRLQMMLAKDIIIDQPTFVGKSSTLQLTFLQGFDTLERLFAPRYYMMVALSRVVCARRFSSSEVRERRIAEFV Polpo ---------------------------------------------------------------------------------------------------------------- Pucgr2 ---------------------------------------------------------------------------------------------------------------- Punst1 ---------------------------------------------------------------------------------------------------------------- Rhior3 ---------------------------------------------------------------------------------------------------------------- Rhoto1 ISVLDSSFNPPTAAHQALA---AHLLALSVGNPDKVTAV-RLEMMLGMDLLLQAPTFVRKSEILRLTFLVGWDTLIRIFAPRYYLGSSMSSLACARRISSTEVRRAVIIDVI Rozal11 ---------------------------------------------------------------------------------------------------------------- Sacce1 LFVLDSSFNPPHLAHFQLLSQTHVLLLLAVNNADKASFPTRLEMMFADYLLTVFSKFIDKDKILDIGYLVGFDTIARIFDEKYYISDVMSQLYCLARVSSSEIRNKLIYDYL Salro ---------------------------------------------------------------------------------------------------------------- Schco3 LSILDSSFNPPTRAHVALADLTPLLLLLAVQNADKASYVQRLQMMLAQQLVTMEPTFVGKARALKLSFLVGYDTLQRILAPKYYMRAALARLVVARRISSSAVRKAVIAEYI Schpo1 IYVLDSSFNPPHFAHLGMCLSIQLLLLLSITNADKAAFNERILMMLKTLIICKHALFVDKCRSIEQVYLVGFDTLIRILDCKYYMQQVLSQILCFSRVSSTRARQAIILNVI Sorma LIVLDSSFNPPTLAHLRMATSARLLLLLAVVNADKAAFDQRLAMMFARDVLTAKPFFHEKSRAMEQVILAGYDTLIRIFNPKYYMQQALAKLRVTMR------RLTE----- Sphar VGVLSASFNPMTLAHVTMATMAAVTLLLTVKNVDKASLPQRLAMLFLESSVCSHPRFVEAAQALRPTFLLGYDTLTRFFDPKYYIGKSLAEVIVYNRASSSEVRECVVKEFI Spipu1 VAILDSSFNPPTVAHAKLLENTAYLLLFATKNADKTSVTDRLLMMLVQTVITTRGIFLDKAHALFLHFIMGYDTIIRFFDPKYYMDTDMSRIICADRASSTKARVMLVMALI Sporo1 ---------------------------------------------------------------------------------------------------------------- Stehi1 ISVLDSSFNPPTLAHLALISSAARLLLLSVRNADKATYLQRMEMIATEDLIVDEPTFVGKSKILELTFLQGFDTLERLLAPRYYMHTALSRVVCARRLSSSEVRARVVAKYV Tapde11 ---------------------------------------------------------------------------------------------------------------- Thetr ---------------------------------------------------------------------------------------------------------------- Treme1 ISILDSSFNPPTTAHLALICAPTRLLLLSLKNVDKATPQQRIEMMLSKEVICHEATFVGKNKVIDLTFLIGTDTLTRFFSPRYYMISLLTTLVSALRVSSTSVRKQVINEYI Trire2 LVVLDSSFNPPTRAHGEMARSARLMLLLSVNNADKASFPVRLGMMFGHGLVTKMPYFHDKARVIEQVFLAGFDTVIRIFNPKYYMKAALARLRVTMRVSSSRVREMVVLGWI Umbra1 IAILDSSFNPPTLAHKELLLRTAYLLLFSIKNADKATAEQRLEMMLAETIVTEHARFFEKANEIQLAFIMGYDTVIRLVDQKYYVGEALNQVICADRISSSKVREQIIYQYV Ustma22 IAVLDSSFNPPSRAHLALLVSRGHLLLFSTQNADKASLTQRVEMMLAKDVLVDKPLIFAKSTLTRLHWVVGFDTLYRVFQLKYYFQQQCTTFVCARRLSSTRIRSLLLVEYL Walse1 ---------------------------------------------------------------------------------------------------------------- Zygro1 LLVLDSSFNPPHSAHQNLVDRAHVLLLLSVNNADKATFDKRMEMMMADNLITTSAKFVDKDRIILISYLVGFDTIVRILDPKYYLSEALTNFFCLTRVCSSNIREAVILEYI [Cluster3570.fasta_al_trimmed; alignment length = 136] Allma1 NIK-LLGQLRKDVVPITLAKQALVASAIQWLNDGAKKAAKVEGR-VAKDGLVAAMVEVNAETDFVARNPLFLSVVHRLAMTASVRDAIVETIGKVGENVTLRRGGAYVHG-KMGAVLARQIAQIVVGVRDYVRFEV Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------- Aurde31 PVK-LIAELRKATVPMNKASEALAACAVAWLEEGAARAAKLADR-VANEGVVAALVELACETDFVARGEMFNKLAADIAHTATITDAIREVVAKVGENVALRRAGSYVHG-RISCLLQRALARQIVGVTDFIKWKV Batde5 NVA-MVSRLRKETCALSKAKDALVAIALAWLHKGAKKAAKVSNR-VTAEGLVAAMVEINSETDFVSKSELFSKLVESVGLTVSIQTAFADVIGKLGENLQLRRAGVYAHG-KFAAVFANKLAQHITGVEAFTRYAC Botbo1 RAK-LVAEIRRRTVSISKARDALAATAFEWLQKGAKKAAKVADR-ATSEGMVAAIVELNCETDFVARNALFGKLACDIAHTASVSSAIRDIIAKVGENITLRRVGHYVHG-RVGGILTRALARQTVGVVDFVRWKV Botci1 ---------------------------------------------------------------------------------------------------------------------------------------- Caeel SKE-ALMALRKKTYSYVNCRKALIQFAVKWLKEGWAKAAKLGTR-VTSNGLVAAVVELSCETDFVARSGAFKDLLSNISNSVNMREVLSLSIGKLGENMTVRRVASHPKG-RFISLLAGQICQHIIGILDFVRVEL Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------- Capow DKE-LLQRLRKESLPFNLCHEALLKNASTWLEKGRAKMEKLKDR-VAAQGIVAAVIELNCETDFVARNPLFVNTAKEIAANATVFDRLVHVVGRMGEKVDLRSAGVYTHG-AKASAIAHGLAVHVLAVRSFTRMVA Catan2 SVK-LIARLRRENVSMSLAKQALTESALAWLNNGASKAAKLAGR-EANDGLVAAMVEVNSETDFVARTDVFKDLAHRCALTATVSERIVECIGALGENISVRRAGAYVHG-RIGAILAQQIAQVVVGVKDYLRFQI Cioin NTKQVLMELRRKTYPLITCRQALQASAKEHLLQGWN-TMQMDGG-VLKEGLIGLIVEVNCQTDFVAKTKEFQSLVKDAAQTLTIEDTVAITIGKLKEKIEIRRAAVYIHG-SYGAMAGRDIAQHIVGVNDFIRFQV CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------- Coere1 DIG-ALKRLRQLNVALSKAKEALLKTAAEWLDKGTQKAEKVKDR-IATEGGIASIIELGCETDFVARNAKFVDLASSIARAGTVADAITESIGRLGENIVLRRAGGYVHG-RIGGLLAKRLAQQVVGVASFTRLRC Conco1 NIK-LIAQIRQKTISISKAKEALVATALEWIQTGAKKGAKLAGR-VASEGLVGALVELCCETDFVSRNDNFHELVQSIAKTVTVKQKINETIGKLGENIILRRTAGFAHG-KIGGLLGRQLARQVVGIEAFSRLEA Conpu1 SVQ-LIGQLRKRTVSISKAREALTATAFDWLEKGAKKAAKVADR-DAREGFVAALVELNCETDFVARNALFTQLAADIAHTASVGSAIQELIAKVGEKVALARAGAYTHG-RVGGLLERALARQIVGVIEFLRWTV Copci SLK-LVAELRKRTVSIVKAREALSASALQWLAKGAKKAAKVGGR-TTNEGLVAAMIELNCETDFVGRNELFGRLAGDIAHTATVATTIRDTIAKVGENITLRRAGQYVHG-RIGTLLERALARQIVGVLEFAKWSV Croqu1 ---------------------------------------------------------------------------------------------------------------------------------------- CryneH991 PVS-LIAALRKQHVPLAQAREALERSALDYLRTAEKKAAKVSGR-DTNEGLIVGMIHLACETDFVARNQVFLDTARGVAETTTIKQSLLSSLAQTGENLKLLRAGGYAHG-KVGGILARTVARQIVGVVGMRRWAV Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------- Dicdi PTE-LVVQLRKKTSPVQECKKALQASAIKWLLEGKATAEKLKSR-VSAEGIIAVILEMNSETDFVSRGDIFRNLARDISKATTIKDSIVRIVSKLRENIVIRRASSYAHG-RLGSIFANQLAIHIVSVKTFRRYAI Dmel EKS-ALAALRKKTYTFANCKKALEKHAEKWLHEGWSKATKVADR-ATAHGLIGAMVELNCETDFVARNDTFKRFVDHVACMCTLGDHLALLIGAIGENATIRRAVGYAHG-KYGAIFHKSICQQIVGIVDYHRFEC Enthi ---------------------------------------------------------------------------------------------------------------------------------------- Falba DMK-LLSRLRKETLSIKHVRTALIKTALEELRKGASVAAKVSGR-SMGEGLVSLMMEMSCETDFVAYSQLMQKTSTSVGERLEVSASMHELVGKLSENIALQRAGSYTHGGRLSASFANKVAQHVVGLAGFERFDV Fomme1 ------------------------------------------------------MVEINCETDFVGRNELFGKLVSDIAHTTTVSSAIRDTIAKVGENISLRRAASYVHG-RMGTLLERALARQIVGVSEFARWTV Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------- Galma1 PIQ-LIAELRKQTVSLSKAREALANSALEWLQHGLAKAAKVASR-ETSQGLIAAMVELNCETDFVSQNELFARLAVDIAHTATVATAIRDTIVKVGENISLARAGTYTHG-PISALLERAIAQQLVGVLDFSRWAV Ganpr1 SVQ-LVAKIRKITVSITRARAALAATAMAWLADGAAKAATLAGR-HAGQGLVAAMVEVNCETDFVARNDVFREACARVGSSVPLSTHLSSAISKVGENLVLRRGGAHAHG-RVAALLARAAAEKVVGLEGVWRWEV Gloin1 NLK-LLQQLRQETVSITKAKEALTKHALSWILEGVAKAEKLKGR-VAKEGLIGAIVEVNCETDFVSRNTLFQQFVTQIASTSTIQESISELVTKLGENISLRRAGGYVHG-RIGGLLLRNLSRQVVGIIDFRRWER Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 SLK-LVAELRKRTVSITKAREALSASALEWLQKGAKKAAKLGGR-PTPEGLIAAMIELNCETDFVGRNELFGRLAADIAHTATVGSSIRDMISKVGENVSLRRAGSYVHY-KIGSLLERALARQILGVLDFAKWKV Lenti61 SVK-LIAELRKRTVSLTKAREALAASALQWLDAGAAKVAKLADR-VAGQGLIAAMVELNCETDFVARNDLFGKLLSDIAHTATVEAAVRDLVTKVGEKVTLRRAFPYVHG-TKAALLERSLGRTIVGLLEFQRWSV Malgl1 SIQ-AIAELRKALTSMLKAREALTASAIAWLEQGAKREAKVASR-VTAEGTIAAMVELNCETDFVARNDIFGALARDIAHTA-VRAAITSVVARLGEKVALGRVGSFAHG-RVASLLARSLARQAAGVAALRRWEV Mellp23 ---------------------------------------------------------------------------------------------------------------------------------------- Mnele SKR-VLQKLRSETLPFIKIKEALQVNALIWLEKNWAKAQKVSGR-ETSHGLVVSMITLQCETESVAKNEHFITLLHQSAVALKLSELFTQTIGRLGENIKTKSCASYLHG-SIGSLTA--IAQHIVGILD--HCKM Monbr ---------------------------------------------------------------------------------------------------------------------------------------- Morel2 NIK-MLADIRKTIISMMKAKEALIQTALEWVREGIKKAEKLKDR-QALEGLIGAIVELNCETDFVSRNDLFKGLVSQIASTATVQESITKMIAKLGENISLRRCGGATHG-KMGALLSRQLTRHLIAVVDALRWER Mucci2 NIK-LLKELRKETVSMTKAKEALVKTALAWLSEGAKKAQKVAGR-TASEGLISTIIELNCETDFVSRNDVFKNLASRIAATSTVQETIVETIGKLGENISLRRAACYIHG-KMGGITARQIARQVVGVVDFIRWQV Mydma NKN-LLTKLRKDTYSFVKCNEALARFAEEWLHDGWNKAQKLSSR-STEQGLVVALVD------------------------------------------------------------------------------- Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ---------------------------------------------------------------------------------------------------------------------------------------- Picst3 ---------------------------------------------------------------------------------------------------------------------------------------- Plicr1 SIK-LVAELRKRTVSINKAREALSASALAWLQKGAAKAAKVAGR-HAGEGVIAAMIELNCETDFVARNELFRKLAADIAHTATVGSAIRDTISKVGEKIELRRAAAYAHG-RIGALLERSLARQIIGVLEFAKWTV Polpo LAP-LIKELRNRTAPLKDCKEALIQNATSWLHEGKSTANKFADR-AVVEGTIAVILEMNSETDFVSRGETFRALADQISRATTVADLIVGTVAKLRENIRLRRVAGYAHG-RLGSLLARNIAVHIVGIKSFVRYSV Pucgr2 ---------------------------------------------------------------------------------------------------------------------------------------- Punst1 SVK-LIAELRKLTVSLTKAREALVATALDWLHKGAKKAAKVAGR-NAGQGLVAAMVELNCETDFVARNQLFGALAADIAHTATVASAIQETIAKVGEKVSLRRAASYLHG-RVGALMERAIARQIVGVLEFAKWTV Rhior3 DIK-LLKQLRQETISMSKAKEALIKTALAWLLKGAKKAQKVADR-TAGEGLISAIIELNCETDFVSKNDVFKNLASRIAATSTVQESIVEAIGKLGENITLRRAACYVHG-KIGGVTARQVARQVVGVVDFIRWEV Rhoto1 PVA-LISKVRSARTPLTLARSALAASALEWIAKGAKKAEKLAGR-EAQEGVVASLVEMRCETDFVARTDEFRELAEGIARSLTVKTSLAQIVSRLGENIHLSRASSYLHG-ALGGLLLRALARQVVAVVELARWEL Rozal11 TIT-NISKLRRQTMPLKVCKEALTLNALEWLNCGYEKLNAVSGR-RTLQGLVLSIVEVRCESDFVSNNKEFIHLTESIGKALSIKSTIAESVGKLGENISLNRLGTYIHGTSCGWVFANRLATHVVGVVDFGHYKL Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------- Salro SVG-NIKELRKRTLPMKLCRQALAESAMEWLKNAQMVKDKLAGR-AAAEGRVAALVKVNCETDFVARNDEFVSMVDEITESCTAKTLIDAALSTHGENLQLSQAGSYSHG-SYAAVTADALAKNVVAVVSFVRWQK Schco3 SLQ-LVAELRKRTVSISKAREALAAAALEWLAKGAKKAAKVADR-EASNGLVGAMIELNCETDFVGRNPLFGKLASDIAHTATVAQAIREVITKTGENITLRRVASYLHG-RIGSLLELAVARQIVGVVDYQKWSV Schpo1 KLA-DIKKLRSETASMDLVKQSVEEAAREILKKGGKLAEKSKNR-TAKEGWIAVMAEINCESDFVAQTTPFQDLARRIASTFSLEEEIVKMTSFTGEKVQVQRLGIFSHG-RIGSMLSNQIAKEIVAILEWVRWER Sorma ---------------------------------------------------------------------------------------------------------------------------------------- Sphar DTK-LLSKLRKDTLSMSKCKEALVTAALEWLQEGAAKSAKLEGR-VAAEGVVGTVVEVNCETDFVSKNQEFRELV-QTAATQTLQTRIDALVGKLGERITARRAAGYVHG-KIVTMIARQIASHVAGVNSIER--- Spipu1 TVA-LVARLRKETCSITKAREAIAATALKWLNNGAKKAAKVGSR-VAAEGLVAALVEVNAETDFVARSKDFSELVQRIGATATVQESIVETIGKLGENIKIRRAGGYVHG-RIGALLARQLAQHIVGIKEFVRWEC Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------- Stehi1 SLK-LVAELRKLTVSITKAREALSASALQWLEKGAKKAAKVEGR-ETGEGMIAAMIELNCETDFVARNDLFGKLVADITHTATVGSAIRDTIAKIGEKVSLKRVGSYTHG-RIGALLERSLARQIVGVLEFVKWKV Tapde11 TIQ-LIKKLREELAPLNLVKSAVSAAALAILKKGEKLVAKSADR-AATEGWVGSLSVLNCETDFVAKSSKVVELASKVGQRLSLKEALTQSMSVYGESMRMTRAGIHCHG-RMGAMMADELAREVVAIVSWTRLER Thetr SMA-LIKELRAATAPLKDCKQALEETAQKWLIEAAKKS---AGR-TANEGLIAVLVEINCETDFAAKNEAFHAFVASLTSRATLDNDIAELTLKIGEPLKLARGGGYVHG-RAGALVARQLAQHIVG--EYVQLAV Treme1 PVS-LISQLRKSRVPLSLAREALAKSALEYLDSA--KADKLSSR-PTSQGTVASMIHLGCETDFVAATRTFQELASGIAGTATVQQRILSSLGETGENLKLLRAGVYSHG-KVASLLARGVARQTVGVVGMKRWSI Trire2 ---------------------------------------------------------------------------------------------------------------------------------------- Umbra1 SIK-LLAKLRQETVSMSKAKEALVKAALAWLEEGAKKAQKVAGR-TAGEGLISTIIELNCETDFVSRNDLFKNLATQIASTSTVQESIVETIGKLGENITLRRVSAYTHG-KIGGILSRNVARQVVGVIDYVRWEV Ustma22 SIK-AIGELRKLVTSMLKAKEALLASALEWLEAGAKKADKVASR-TAREGVVGAIVEINCETDFVAKNEVFAQLVKDVVHTVTVGSAIIDVVSRLGEKISIARASAFAHG-KVASLLTRSLARQVAGVVDMHRWEL Walse1 -TE-LVKLLRNTYCSITQAMAALKDGSKKAIETSTKKAEKALNRGVGSEGLIGGILQVNCETDFVARTTNFKQLVQDVSHTLSIKDAITQTIANVGENITLQRFGQFTHG-TLAGLLAKKIARQSVAILDFKRWSI Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------- [Cluster3577.fasta_al_trimmed; alignment length = 188] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 IAEFAVLQHKPGKERALEMLQDIARRVSYLMREEGFRVGQLAEFYPRERRLLGLNVNQGARILLRLRDEQQFLSRETILAVML-HELTHNVFGPHDARFRRKLDELVGRVDSFLGRGRRLG------RRLEGR---GRRLGGAARELAGLAAARRATAQCCGGGT-------A---------CVVRTP Aspfu1 VSEYQHDKHRPREAEALLMLRKIASLVKPIMRQRAWRVGTLCEFYPQQRNLLGLNINAGQKICLRLRDERQFLPLEQVVDTML-HELCHIVHGPHNQQFHALWNQLRDEGEGFLSQGKRLGARRVARAAAERRAGSGQRLGGDMRRVIADAAQRRDVTKGCTKAEEDDANERATCTLENCDACASERP Aurde31 VHKFTHLKDKPNAARAQAILERMASLVKPIMRKHDWHLPALAEFFPKNANLLGADVNRGQKILLRLRDEAAFLEEEDILGTML-HELTHNVHGPHDEKFYKFLGTLEDEGEGFHTPGVRLGARKKALEEAEKRAGGSR-LGGSLRE---LAAEVR--------------------------------- Batde5 -MELRPLKRRQNVNTAQKLLERIYSDVQPIMKLHNFRVGSLQEFYPTNPNLLGLNVNHGQVIRIRLRDDNQFLEFHDLIGTML-HELAHNVYGPHDAKFYKFLDRLFDN--GFRSNGNRLGFKKESIAAAEKRPVGGRKLGTTPAQLAAMAAERRQDSKWCSQKDMEHDHFCPTCTLINCECCLAIRS Botbo1 IKAFTHLKGRPHEDKALETLQKIASLVKPIMKAHGWTLPVLAEFFPKSDNLLGLNVDAGQKILLRLRAPNTFYELGQLVLVML-HELTHNVHGPHDEKFYKYLKGLEDEGEGFHGKGTAVGARLKALEAAEKRGRGGR-LGGTPRELAAQAAERRRDQTACAEEETARAAEEGACTLLNCLACLSDRP Botci1 ISSYSHLKGMKREAEALHSLKKIASLVKPIMRARHWRVGTLTEFYPDQQNLLGLNVNRGQKICLRLRDQNQFLPIEEVVDTML-HELCHNEIGPHNQEFHALWDQLRKEGEGFLSEGKSLGARRLARIAAEKRKGSDQKLGGDIRKVIVDAIERRKVLKGCTLAEEDLANDAAIYLFH---------- Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 IKKIGALKRFSDEAYAKSLLYDAARLVAPIIHEQKFKVGKLYEMYPDKAELWGLNVNHGQKIYLRLRNDKSFLPMGDIVGTLL-HELTHNLYSAHDSKFYKFLDKLKSRKTKYLCEENKVG-----VSVREQRANESKVLGSDLRQAILEAAERRRDSKWCSENA--ETESV---------------- Cangl IRNIAVLQRKPGKEDALKLLKDIADAVSLLMRENKFKVGTLVEFYPRDRSLLGMNVNHGQKIMLRLRDEFRFLPWESLIGTML-HELTHNLHGPHDQKFYSKLDELSGRKDNFMTSGNRLGSRGNKIEKIRNK---GVRL-GKPAQMAAMAATRRADKKWCTNQEEKI-----------NDVRKVDEP Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 IGTVLSLKRQKNSDKALDMLMQAANL-----------------FLPKDPMLLGLNVNRGLEIRIRLRAPDKFYPFDDILGTVLTSRLVHNRISPHNDAFNALLDELWRE-----GDGARIGSKKAAADAAERRSGGGQRLGGTPREAAAQAALRRMDATRC------------VVVLLS----GQRRP Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 FDAYEHLKHLPRDGEALHTLRKAASMVKPMMRKRGWKVGILAEFLPDEPQLLGLNINRTERILIRLRDSRQFLSLEQVTDTLL-HELCHIVIGPHNVDFNNLWNELREEGEGFLSQGQKLGMRRQARIAAEKRAG-GHRLGGDMRKVIADAASRRSITEGCTTAEQDDANDWAQCTLHNCGACGLEQP Coere1 ------------------MLQRVSAQVRPIMQRHGWRVKVLREFYPRTANLLGLNVNCGQEIRLRLRDDGLFLEYTEVLGTML-HELVHIVRAPHDSEFYRRLDELRIEGDGFHSDGRRVGLREKRLRAVEGRGGRARTLGGTPAQMAAMALERRRDERWCTKDDSEDDVVVIVCVIED--------- Conco1 --------------------MRMAKQVEPILKKRRWKVQNLREFFPKNPNLLGTNYGRVITISIRLRNKDEFLPYEECMGTLL-HELTHIVHSDHNDLFNALLKDLEEE---FSGKSYRLG---------ESN------VGS-LKWKVYFAAQSRNGNTIC------------MCTFKNCEICCNTKP Conpu1 VKSFTHLKGRPHEARALQFLQTVASLVKPIMRKHGWTLPALSEFFPSNPSLLGLNINGGQKIFLRLRAPDTFYDEDHVVRTML-HELTHNVHGPHDDKFYKLLGELEDEGEGFFSKGQRVGGRAKALEAAEKRSGGGR-LGGTPREAAAQAAERRHDEIACAQREAEKAARESTCTLVNCDACLSERP Copci VKTITHLKDRPNADHALELLKKTASLVKPIMRKYGWILPELSEFYPDNPNL--LDVNAGQKILIRLRSPTWFYDLEDIVGTML-HELTHNVHGPHDDKFYTLLNKLQEEGEGFYSPGHRLGARQKALEAAQKRGSGSRTLGGSPRELAARAAERRRDAKSCAERESAKAAQEGQCTLINCDAC-GFRP Croqu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 VLSYRHIRELPRADEALHSLRKIASLVKPIMRARGWKVSELCEFYPSQQNLLGLNVNRGQKIMLRLRDRSQFLPIEQVTDTML-HELAHIVHGPHDAKFHALWDQLRDEGEGFLSQGHKLGARRLARAAAEERRGSGQRLGGDIRQVITNAVERRRMDRGCTQAEEDAANEAAICTLHNCDACGTTRP Debha1 ISKIGSLKRFSDQDYANSLLHQVAKLVAPILHMNNFKVGTLCEMYPKNPNLLGLNVNRGQKILIRLRNDKLFYPLGDIIGTML-HELTHNLYGPHDAKFYKFLDGLKKDKSNYVCEEQTLG-----ISVREKRKSESRKLGTALRKLILEATERRKDSKWCTAEV--DTKDIE------VRSVGDKLV Dekbr2 IGNIAALKRMASRSQALELLHDIAKKVTPIMSFYGFNVGTLCEMYPKNPRLLGLNVNGGSKICIRLRNKNWFLPTQDLIGTML-HELAHNKCGPHNAVFYKLLDQLKEKATGYFMESCKLG------SVRTQRTTKNSKLGT--RKLLREAVERRKDEKSCSHLSILEMESII------CNAKG---- Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba VRRVEGQSSRPAADYALGLLQRLVEDTKRVLELRGWHVGLLKEFYPKNPQLLGMNVNYGQTILIRLRRDSAFLDYEDILETML-HELAHNDIGKHDESFFALLEELRFESRLLSGSGAAGGP-----AAGPAR------LGASARQMAAAAALRRAATTGSGPASEAHARSPACCSADRPDLCALIDL Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 VLSYSHLAKFPRASEALQTLKKVASIVKPIMRARNWKVRQLAEFYPEQHNLLGLNVNRGAKICLRLRDRNQFMPIENVVDTML-HELSHIVHGPHDAKFHALWDQLRDEGEGFLSEGRRLGARRLAREAAEKRAGSGKRLGGDIRRVIADAAERRSTLKGCTQAEEDEANDAATCTLRNCDACGMERS Galma1 VLSFTHLKDKPNANGALHILEKVASLVKPIMRKRGWVLPVLAEFFPDNPNL--LDVNMGQKILVRLRSPDSFLPEEDVVGTML-HELTHNVHGPHDDKFYKYLDGLQDEGEGFFSEGKRLGARLKAMEAAEKRGSGGR-LGGTPRELAARAAEKRRDEKSCAQREADKAAKESACTLLNCDACQLRKP Ganpr1 IGQFRVL-KRPDEAAAMALLKQVASQVKPIMKKRGWRVGTLEEFFPSNSSLLGLNTERGQKISIRLRSPSSFYPLHHCIGTML-HELAHIIRGPHDAQFYAALDELEKEGEGFEAPGRRVGARERAVEAAEKRPGGGRKLGGSPREMAAWAAERRKDREWCGQGSADAGTVSAVCTLSNCDACGTLHP Gloin1 ------------------------------MNNRNWRVGSLEEFLPDQANLLGINVNHGQKICIRLRNQSRFYDFDHLIETML-HELTHIKFGPHDSSFYNLLDELNDEGGGFFSDGKRVGARQKALEAAEKRTNGGRRLGGPTRELAAMAAERRRDNFWC------EQNRSGQCTFINCDVCLAERP Hisca1 VSEFEHLKHKPREAEALTTLRKIASLVKPIMRQRGWKVGTLAEFYP-ERSLLGININHGEKICLRLRDDSQFLPLDQVLDTML-HELCHIVHGPHNQEFHALWNQLRDEGEGFLSEGKRLGARRIARVEAEKRAGSGRKLGGDIRQVIADAAQRRTVTKGCTKAEEEDANEQAVCTLVNCDACTLERP Klula1 VGSIAVLQTKPGKNDALNILKRVAHNVSYLMKEERFKVRQLVEFYPRNRSLLGMNVNKGMKIMLRLRDEYKFLPIESIMGTML-HELTHNLHGPHDRKFYEKLDQLSGRYDSFLGTGKRLGIIGKTLERGKGR-----RLGGNAREMAAIAADKRADNKTCSNDQKNY-------------------- Lacbi2 IQSFTHLKDRQNADRALHMLKKVASLVKPIMRKHGWVLPVLAEFFPDSPNLLGLNVNMGQQILIRLRAPDTFYDQEDIVQTML-HELTHNVHGPHDDKFYKFLSGLQDEGEGFFSKGQRLGARAKALEAAEKRGSGGR-LGGTPRQLAAEAAERRRDEKSCAQREAEKAAREGMCTLLNCDACMTKRP Lenti61 VQAFTHLKDRPRADEALDVLQRVASLVKPIMRKHGWVLPVLSEFFPESPNL--LDINSGQKILVRLRTPNTFFDEEDILQTML-HELAHNVHGYHDDKFYKFLAGLEEEGEGFHSAGRRLGARQRAVDAAEKRSGGGR-LGGTPQELAAEAAERRRDDKACALQEADKAAKESRCTFINCQACLALRP Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 VSSFTCLTSKHNHEEAMRLLKKVATMVRPIMKAHGWKITTLAEFY--TKGLLGMNTNRGWKIQLCLRDENTFLPWEDILGTML-HELAHNIRGPHDQQFYKALDGLNDEGEGFDTAGHRLGTRAAAVVAAERRPAGGRKLGG---------------------------------------------- Mucci2 VKEYKALVRKPRHDEALQLLKRLASQVKPVLLKHNWTIKNLVEFFPNNPNLLGMNTNKGWKVNLRLRDETQFLEYEDILGTLL-HEMAHIVRGPHDEHFYKLLDELKQEGEGFYSDGHLLGSSGIAAKAAEKRPTGGIRLGGTPAQAAARAAQKRLDKVWCAQQDSSSSSSNSTCTFLNCQICLTERP Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 VLAYSHLHHLPQPSSALHLLKKIASLVKPLMRARGWRVRELGEFYPEQDNLLGLNINRGAKILLRLRDKSLFLPIEQVADTML-HELAHIVHGPHDAKFHALWNQLRDEGEGFLSEGRRLGARRLAREQAEKRAGSGQRLGGDIRRVIVDAVQRRKTLKGCSKAEEDEANEAAICTLHNCDACGTERP Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ISEYRHEKKRPREAEALLILRKVASLVKPIMRQRAWKVGALCEFYPQQRNLLGLNVNSGQKICLRLRDQRQFLPIEQVIDTML-HELSHNVIGPHNQQFHALWNQLRDEGEGFLSQGKRLGARRQARAAAEQRKNSGKKLGGDIRKLRADAAQRREVTQGCTQAEEDDANERATCTLENCDVCAAERP Phybl2 -MIYKALK-KPKEDQALDILKRVASQVEPILTKRAWKVTHLQEFFPSNPNLLGTNVNRGHTINLRLRDDKLFLDYEDILGTML-HELVHIVRAPHDATFYKMLEELNQEGQGFYSMGNRVGVKYRAATAAEKRPVGGICLGGSPSIMAARAAEKRQDQVESRKRDQNHPVKKKTCTFQNCEMCLSIRP Picst3 ITKIGSLNRYADKEYANDLLHQVARLVAPIIHENNFKVGTLCEMFPKDANLLGLNVNRGQKILIRLRNDRLFYPMGDIIGTFL-HELTHNLYSAHDDKFYKFLDGLKKRSTTYRCEEETLG-----MSEREKRKTELRKLGTQLRQMILAAAERRKDNKWCNHNS--DITEIE--------------- Plicr1 VKSFTHLKDRPKADQALAMLQRIASLVKPIMRKHSWVLPVLSEFFPDDPNLLGLNVNGGQKILVRLRAPDTFYDEEDVMGTML-HELTHNVHGPHDQTFYKFLEGLQDEGEGFHSKGHRVGARAKALEAAEKRSGGGR-LGGTPRELAAQAAERRQDEKSCAQREVDKAAKDSVCTLLNCAACLSARP Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 VASFTHLKDRPRADRALEQLKRLASLVKPIMRKHGWKLPVLSEFFPDNPSLLGLNVNAGQKILVRLRAPDTFYDEDDLVHTLL-HELTHNVHGPHDDKFYKFLAELEGEGEGFYSLGHRLGARQKAVEAAERRSGARR-LGGSPRELAAEAAERRRDAVSCAQQEAEKAAKESTCTLLNCTACLSPRP Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 VGTFTVLKSQPKSDEALALLKRIHSMVKPIMKKHGWFLPTLAEFYPLQENLLGINVNRGWKICIRLRDPHSFLPLEDLIGTML-HELSHNIRGPHDDIFFKTMDGLYDE--GFVGEGRRVGVREKALKRMEEAGQGGK-LGGRRGDILADAAERRRAQKACIQDAINQADRDSLCTFRNCEICGTERP Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 IQKVAVLQSKPNKEDALNLIKEIAHKVSYLMKENHFKVTNLVEFYPRDQRLLGMNVNHGSKIMLRLRDEFQFLPMECIMGTML-HELTHNLFGPHDKKFYNKLDELIGRYDTFLGNGQRLGSTNTGIVRKRGK---GVKL-GSPRELAAFAAERRRDDRWCTKNNKDQI--IS--------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 VRTITHLKDQPRGDEALDMLKRVASLAKPIMRKRSWHLPTLGEFLPDDPNLLGINVNRGHQIFLRLRNPSTFYDLEFVMGTML-HELTHNHRGPHDEVFYKYLDGLEDEGEGFYSRGRVLGDKRRAAEAAEKR--GARVLGGSPREAAAQAAIRRRDSHSCAQQEAQKATQASICTLVNCDACAALRP Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma VLSYSHLHHLPQPSSALHVLKKIASVVKPLMRARGWRVRELGEFYPEQENLLGLNINRGAKILLRLRDKSLFLPVEQVTDTML-HELAHIVHGPHDGKFQALWDQLRDEGEGFLSEGRRLGARRLAREQAEKRAGSGQKLGGDIRRVIVEAVERRKTLKGCSRAEEDEANEAA--------------- Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 ------------------------------MKAHGWILPTLAEFFPKNPNLLGINVNRGRKICIRLRDPYTFLPLEELIGTML-HELTHNHRGPHDEIFNKFLDGLWNEGEGFLGTGRRVGAREKALKLFEEKGTGGK-LGGRLGDILADAAERRKARKGC--EFVSKGKQRALCTYHNCSVCLSQRP Stehi1 VTSIEHLKDRPKANEALKILQRTASLVKPIMRKHSWRLPTLGEFFPNNPSLLGLNINGGRKILIRLRAPDSFYPEEDIIGTML-HELTHNVHGPHDEKFYKYLSGLEEEGEGFFSKGHRLGARQKALQAAEKRGGGGK-LGGSPREVAALAAERRKDAKSCAEREAEQAAKDSVCTLINCDACASPRP Tapde11 VDTFIHLKKKPKAKEALDLLKRVAAHAKPIMESHHWHIKTLAEFFPTQTKLLGTNYGKGIKISLRLRNDSEFLSFDDIMGTML-HELSHNVHGPHDAKFYALLDDLNLKGD----DGDSLGARKVAAGKALARGSTGRQLGGTLREKVATAAQRRHDAKWCGDETRDEKVSEALCTLLNCAACEAERP Thetr IGKVTVKDMQDKA--ALELLTRVVDDVRRIVDDHGWRVGMVGELTSSNRRLLGLNVNAGQKILIRLR---PLFPYDDVMETML-HELAHNDVGPHNTAFYALLDKLRGESRPFAGSGRTLGPRGPPVAAASAAMGSGV-LGSTPRELRARAAEQRRDQVWCATAAAEVAVDAACCTLVNCDACGSTRS Treme1 VGRFEHLPNRPKSDAARPLLEKIASQVKPIMLKRGWKVGTLAEFTPADPSLLGNNTNKGERINLRLRSPSSFYEFDQLVLVML-HELTHNEFGPHDASFYKLLGELEEEGEGFHSSGHHLSGRLKGLTAAQKRGKGGV-LGGSMKEIMAEAAERRRDDKACVEEEVRKAQNESTCTLLNCEACDTARP Trire2 VLSYSHLAQFRRADEALTILKKVASLVKPIMRNRGWKVRELAEFYPNETNLLGLNVNRGMKICLRLRDQNQFLATESIVDTML-HELCHIVHGPHDGKFHALWDQLRDEGEGFLSEGHRLGVQRLARSAAEKRRGSGRRLGGNLRQAAAAAAEKRKALQGCTQAEEDEANDLAICTLHNCGACGVERS Umbra1 IEEYKALKKKPKSDIALNLLKRLASQVAPIMKKRGWKVKQLAEFYPSNPSLLGLNVNKGYRIDIRLRDASEFLPYDDLLGTLL-HELTHIVRGPHDVQFYKILNEVNAEGEGFYSQGKQLGARKKALEAAEKRPAGGRRLGGTPQELAAEAAERRRDNIWC----------EAYCTFMNCSMC--LQE Ustma22 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 IQRVAVLQRKPSRDDALSLLKEIAKRVSYLMKENKFRVGMLVEFCPRDKRLLGMNVNRGTKILLRLRDEFRFLPMESIMGTML-HELTHNLHGPHDNRFYAKLDDLLARFDTFLGQGSRLGQLQKRPTRSRGR-----KLGGTPREMAALAAQRRQDSRSCASSYQHE-------------------- [Cluster3580.fasta_al_trimmed; alignment length = 119] Allma1 ----------------------------------------------------------------------------------------------------------------------- Ashgo11 DGGSAEQGGSSSSESSADESKNELDFVVESIGTIKSAFDQNIIVQAVLQEGSIFADRTVVGPVCEVFGKLSNPFYRVNQLGAQVFLVRGTDASNGVDEEVPEDEQEFSDDEA--EAEFK Aspfu1 ----------------------------------------------------------------------------------------------------------------------- Aurde31 ASTAHDGNARDSSDSD-SDTAHEIEVGPDEIGEVMSVIDSVVVIKGVLDTDTLLEDRKVLGQIFETFGPLKQPLYSVVTVGRAIFHVKGSDASNYYDEEPGDDELEFSDDEQ--EAAHR Batde5 EVAGGDGSESKVTFSD-SSTKNEAEIPTHLIGAISAIVDTLVVIKAVLDADSILQDRSILGRIFDTFGPVNEPLYTVAAVGTSVYFIKGSDASNLYDEEVAADEIEYSDDEK--EIEHR Botbo1 ----------GKGIED-ADTKHEIEVGPEEIGEVMSVIDSVVVVKGVLDTDSLLDDRKVLGQVFETFGPVSAPLYSIIRLARTVYHVKGSDASNVFDEEPADDEIEFSDDEA--EILHR Botci1 ----------------------------------------------------------------------------------------------------------------------- Caeel ----------------------------------------------------------------------------------------------------------------------- Canalb1 ESSGDSSSDE--DENETSNSVHEIEISPNTIGEITGLVENTMIIKAILQEKSIFEDRTVIGPLFEIFGRVQQPVYSV---GKTVYYVKGTDASNCHDEELPEEEQEYSDDEK--ESAAK Cangl DSNSNLNEDSSSLDSSSSQSKNEVSYVIDEIGTVKSVLDNNLIITAVLEEGSIFEDRTPLGVLREVFGPLQAPFYRVSLIGIKVFIVKGTDASNMFDEELPEEEQEFSDDEK--EAMYK Capow DASSSSDSDDDNSDGSSSSTRNELSDVAHVIGHVHSVIDTIVVVESALDIDSVLEDKLPIGRIFDVFGPVKQPHYSVLSVGTRLFFARGTDASWLHDEEPPAEAIEFSDDEE--EEAAK Catan2 SSSASDASSSVGNSDSDDGTANEIVITPDMAGHVHMIVQDQVIILSVLDDGTVLDDRTVLGRLFETFGPVAKPMFSVVVKGKTVYYVRGCDASNAFDEEVGDKEMEFSDDEE--EARWK Cioin ----------------------------------------------ALNLDSVLEDKSIVGKIYETFGPVPSPYYVV------IYFAKGSDASWKDDAEPPDQCIDFSDDEE--E---- CocheC53 ----------------------------------------------------------------------------------------------------------------------- Coere1 ESSASTSSDLNEADSD-GQTRHELQLPDTALGAIHSIVGSSITIQAVLDSESLVENRKVLGMISDVFGPVARPMYTVCTVGRSVFYAKGTDASNEYDEEVGSDAMEFSDDEA--EQAFK Conco1 NAAQDVQYDSSGSDSDSDDSENESPLPLDTLGVVYSNKNATIVIKSALDLDSTLNDLTVLGTVHETFGPVQDPWYSVFPEGAEVYFVKGSDASNLYDEEVGEHELEFSDDEE--EQLYK Conpu1 DSDSDSDADSNTSIAAGSETVNEVKIGPDDLGHISRIIGNVVIIEGTLDAETLLEDRSVLGHIYETFGPTSAPLYQVVYIGRDVFHVKGSDASNMHDEEPAEDELEFSDDEQ--EVAAR Copci DSSSESSSDSESDGKEVGKTKNEIEVGPDEVGVVMSIVNQIAIVRGALDSETLLDDRKVMGYIYETFGPTSQPLYQVVKVDREVFAVKGSDASNVYDEEPADDELEFSDDEA--EAAYR Croqu1 ----------------------------------------------------------------------------------------------------------------------- CryneH991 DSSSEFESSSESEDEKAADSRNEVKLPEGEAGDVVSWMPGTVVVRAWLEEGSILEDGRVMGTVYETFGPLTSPFYTVLATGTRLFYPKGTDASNIYDEEVAEEEMEWSDDEA--EAAAK Crypa2 ----------------------------------------------------------------------------------------------------------------------- Debha1 DSSSDSDSDSEGDDKKVSASKNEVKIPDNAIGEITGLVEKSAIIKAVLNDSSIFEDRTVLGPLFETFGRLQSPMYRV---GAKVYYVKGTDASNCHDEELPEEEQEFSDDER--ELAAK Dekbr2 ----------------------------------------------------------------------------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------- Fomme1 PSSSESSSDDSDGDSDAEETKNELEIDPQEVGEIMSIIENVVVVKGALDSESLLEDRKVLGYIHETFGPTYQPLYQVMSVGREVFHAKGSDASNVHDEEVNEDEMEFSDDEA--EAAYR Fusgr1 ----------------------------------------------------------------------------------------------------------------------- Galma1 SSESESDSDSDTSDSSHDGTKHELEVGVDEVGEVMNILDRVAIVRGALDSDTLLEDRKVMGYIYETFGPTTQPLYQVVRVGREVFHVKGSDASNVHDEEPADDELEFSDDEA--EAAYR Ganpr1 ----------------------------------------------------------------------------------------------------------------------- Gloin1 DSSSEDSSVSEMADVD---TKNEIEITSDMIGSILHVVEDQIVIKVILDVGTVLEDKEVLGEIFETIGPVAHPMYVVVVRDAKVFGVKGCDASNAFDEEVNEEEIEFSDDEK--EKAFN Hisca1 ----------------------------------------------------------------------------------------------------------------------- Klula1 D---------DDGDDDGDDSVHELDFIIDEIGTIKSAFEHNIIITAVLKEGSILQEKTLVGPVCEVFGPLQAPFYRVTKVGAKVFYVKGTDASNGFDEELPENEQEFSDDEK--EMEFK Lacbi2 DSNSESDSGSEQQQHDSDDTKHEIQVGPDEVGEIINIMDRVVIVKGALDSDTLLDDRTLLGYIYETFGPTSQPLYQVIRLSREVYHVKGSDASNVHDEEPADEELEFSDDET--EAAFR Lenti61 -SESTSDSDSDSEDEEDVSTKNEVEISPDQVGEIMNIVDKVVIVKGALDSDTLLEDRKVFGYIFETFGPTSEPLYQVVQVGRPVFHVKGSDASNVNDEEPADDELEFSDDEA--EAAHK Malgl1 ESTVSSPTESETESSSELDTKNELHVNQDDIGTIHSVVDNVVLIEQVLDSESLLENGQVLGLVYETFGSVQKPMYTVIQIGRAVYFLKGSDASNMWDEEVAEDEVEYSDDEE--ELSAK Mellp23 ----------------------------------------------------------------------------------------------------------------------- Mnele EDSSDDGSDDSGDDSDYRDTFPEVDLTLSELGKVFKIVEDFVVVNSVLDLDSMIADRKCIGYVFEVLGQVKEPYYSILRLNQELFYSKQRRASDSGGETSSDNCNSGSEGEEIPDQVIK Monbr ----------------------------------------------------------------------------------------------------------------------- Morel2 ESSGDDDDEPSDSDSD-SDTTNEIDLGPDVFGSVMSIVDNVVVVQAVLDSGTVTAVREVLGEIFETFGPVARPLYSICKIGSTVYSIKGSDASNKFDEEVDDVELD------------- Mucci2 --MGDEDD---EQYPD---TAHEIEMTPQTAGSIFQIIDNVIVIHCTLDQGSLLENREVMGEVFETFGPVARPYYSVAKVGQDVYFVKGTDASNVYDEEVGEDV--------------- Mydma SSSSSETEDSSSSEVQVIEVHNEVKLTKEDVGSILSVVDKLIVVEAALDAESAFSSEHYLGKVFDTFGPVKHPYYTMLSKGTKVFFVKGSDASWKGDQEPPVEFLDYSDEEE--ERKAK Neucr2 ----------------------------------------------------------------------------------------------------------------------- Orpsp11 ----------------------------------------------------------------------------------------------------------------------- Pench1 ----------------------------------------------------------------------------------------------------------------------- Phybl2 EMSSDEDSDSDESDEE-VSTTNEIILTPQTIGTIHNVINNVIVVQTALDIGTLFGDRELMGEVFETFGPVQRPFYSVAVVGARVFFVKGTDASNIYDEEAGEDELEFSDDEK--EMEHK Picst3 ----------------------------------------------------------------------------------------------------------------------- Plicr1 DSNSESDSDSSDSDSEPDPTKNEIEVGPEEVGEVMNITDRVVIVKGALDSDTLLEDRKVLGYIYETFGPTHQPMYQVVRISRQVFHVKGSDASNVHDEEPADDELEFSDDEQ--EAAFK Polpo ESSSESSSSSSESESESSDNKRKVTLPPNTLGTLSSLVDDMIVIKSALDIDSIVEDRTPIGRIYEVFGQISDPYYSVIELKTPIYYVKGFDASNENDDELEENEMDFSDDEK--EREFK Pucgr2 ----------------------------------------------------------------------------------------------------------------------- Punst1 DSDLEDDSSSSESDQSISGTQHEIEVPSDEVGEVMTVLPQTVVIKGALDSETLLEDRRVLGYIYETFGPTHQPLYQVVQVSQPVFHVKGSDASNIHDEEPAAHELDFSDDEE--EAAFK Rhior3 EFSSDDDDSSEEKEEDTKETANEIDLTQQTAGNIFQIIQNVVVVHSALDAGSLLENREVMGEIFETFGPISRPYYTVTTVGAAVYYVKHTDASNFYDEEIGEDV--------------- Rhoto1 DDSSSDSSDSDSSSAESDSTEHEVKL--DEFGKVESVIENVVVVKAVLDEGTVVEDKTVIGTIFETFGSVQQPFYSIFTISRPVFYSKGSDASNIWDEEVAAHEVEFSDDEE--EAEYR Rozal11 ----ENDCDSTSSESEGEQTKNEL----DKLGTIFSALDDNIVIQTPLNLDSLIEDRQILGNVFDTFGPIVCPFYTV--IGKNVYYVKGTDASNQYDEEIDADEIEFSDDEK--EMEYK Sacce1 ESDSGSDSDSGSEDDSADQSKNEIDYEISEIGVLKSAFENNIIIHAVLKEGSIFEDRTLIGMLTEVFGPLQNPFYRIVRLGEKAFIVKGTDASNGYDEELPEEEQEFSDDEK--EALFK Salro -----------------------M------LLLCYFHFEKVVV---ALDVGSVLEDRSPLGKVFEVFGRVDEPYYVVIAKGQPIFAAKGSDASWFHDEEPPENALDFSDDEE--EAKHR Schco3 DSTSDSDSDSDTSSEDDAQTKNEVAVEPDEVGQIMNVLEDVAIVRGALDADTLLEDRSVFGHVYETFGPTALPMYQVVRVDREVFHVKGSDASNMHDEEPGEDEVEFSDDEA--EAAFK Schpo1 KSSADLSSDSSESNTSFSETVNEL-LQPNSLGKIIQVLKREVVVKSVFDEKTVLEDRSIIGYIHETFGPVSSPYYIVACMGRPVFYVKGSDASNVYDEEINPSEQEFSDDEA--EVAAK Sorma ----------------------------------------------------------------------------------------------------------------------- Sphar ESSSDEESSA--SEDEILETANELDLPAHAIGTVTSYVDGLVIVTAALDVDTILDKQTPLGRVWDVFGQVEQPFYSVVLIGKSIAFVKGTDASWQHDEEPPENEMEYSDDEE--EALAK Spipu1 EGDADEGEGSEFSDED-TSTKNELPIPQDAIGTIHSTVDDLLVIQSVLDADTIVSDRTPLGRIFETFGPVTKPLYSISGTGTEVFVAKGSDASNIHDEEVGEEEMEFSDDEQ--EAEFK Sporo1 QDSDSSSSDSDSSSLDSDSTEHELKI--DEFGKVESVIETVVVVKAVLDEGTVVQDKTVIGTIFETFGSVQQPFYSLFSLQKPVFYAKGSDASNVWDEEVGAGEVEFSDDEE--EAEYK Stehi1 -------------------TKNELEVGPDEVGEIMSVVNNVVIIRGALDSDTLLDDRKVMGYIYETFGPTYQPLYQVVTVGREIFHVKGSDASNVHDEEPAEYELEFSDDEE--EAAHK Tapde11 DDSSDISSDSDESDASMEDTKNEIEIDASELGTITSIVGSACVVTGVLDVGSLLEDRKNLGYIADTFGPVILPMFTVVAAGKKIYVVQGTDASNINDEE--QSETEFSDDEK--EAMYK Thetr EASSSSSSSSEASDCEGSDTANEVSVAADEVGTISSQLDAVVVIKGPLEEGSILQDRKVIGAVAETLGPVQSPFYTVLALRAPVFTPQGSDASSWNDEEVADHERDFSDDEA--EMAAR Treme1 DSSSEWESSDEEEKENGS-SVNEEKLPKGEAGEVVSWMKGTVVIRAWLEEGSVLEDGRVLGTVSETFGPLTSPFYTVLNAGTKLFYPKGSDASNRYDEEVGEDELEWSDDEA--EAEAK Trire2 ----------------------------------------------------------------------------------------------------------------------- Umbra1 DSSDDEDNAPEDNDSE-SDTRNELTIKPEAIGSVYAVVGDTVVVQGVLDSGSLFEDREILGEVFETFGPVARPLYSVTKQGAKVYIVKGSDASNIFDEEVADHEMEFSDDEA--EQAFK Ustma22 DESDDDGSSSGSSS----STKNEIELTAEELGRVHSIVDSVVVVEQVLDTGSLLEDGKVLGLVFETFGSIHNPMYSIISAGKEVYYLKGSDASNMWDEEVAEDEIDYSDDEQ--EAEAK Walse1 DSGSDQNKNNEDDDSDADDTKNELKFPVDIVGHLHSLIDNILVIQSTLDQDTLIEDGTLIGEIFETFGSISSPFHSISK--QKVFYAKGSDASNVYDEEIPENQQEFSDDEA--EQSAK Zygro1 SSSSYESEDS-EEEEVAEYSKHEVDYEIPEIGKIKSAFDNNIIIEAVLKEGSILEDKSLIGILCEVFGPLQKPFYRVEQLGSNVCIVKGTDASNGYDEELPEEEQEFSDDEK--EAISK [Cluster3582.fasta_al_trimmed; alignment length = 48] Allma1 ------------------------------------------------ Ashgo11 KKFPTPVLKPFWPFFVSGAAIYWAMSKLADASSNSAEFINDPRHPRFA Aspfu1 KKFPAPVAKPMAPFFAAGVVILYGVNSLANALMNTEEFKNDPRNPNAK Aurde31 RRFPVPIVKPLYPFFVAGAVTFLLVGKLQNLMLNSAEFANDPRNPYAA Batde5 ------------------------------------------------ Botbo1 RKWPTPVARPMYPFFLATGVTYYLVSLAQEAGSSSPTFANDPKNPHAV Botci1 KKFPAPVAKPMAPFFVAGAVIMYGINSAAIAMSNSEEFKNDPRNPNAK Caeel ------------------------------------------------ Canalb1 PRYPFPVLKTYWPYAIGAGITYYLVYKGSIASANSDEFINDPRNPRFA Cangl KRFQFPVLKTYWPFFAAGAVVYYGVSKAATAMSNSEEFINDPRNPRFH Capow ------------------------------------------------ Catan2 ------------------------------------------------ Cioin ------------------------------------------------ CocheC53 RKFPAQIAKPMWPFYVSGLVILYGVNSAANAMSQADEYKNDPRNPALK Coere1 ------------------------------------------------ Conco1 RTFNTPIVRPLYPFFVGMAITFYGVAKLQASMLDTEEWRNNPQSPTYQ Conpu1 RKWPTPVLRPMAPFIAAAGITFFLVGKMQDMGIRSEEYAKDPRNPYAA Copci RKWPTPIAKPLWPFMVAGSITMYLVYGAQQSGVRSAEWRQDPRNPYAA Croqu1 RAWPTPVWKPMSHFIIGGAATFYLINKIQNSMLASPTYAKDPRNPFAA CryneH991 RAWPTPIVKPLWPFMVSAVITTAGVWAVQEKAVSTPDALKDPKNPFAA Crypa2 KKFPAPVLKPMAPFFAAGLVIAYGINAAQNASMKSDEFKNDPRNPLAK Debha1 PRFPTPVIKHYWPFAVGAGITYFLIYKASVASMNSDEFINDPRHPRFA Dekbr2 KVYRYPVFKTYWPFFVGAVATYYLIGKAQSAMENSEQYINDPRHPRFR Dicdi ------------------------------------------------ Dmel ------------------------------------------------ Enthi ------------------------------------------------ Falba ------------------------------------------------ Fomme1 RKWPTPVAKPLAPFVAASAITFYLVSSLQNMAVRSETYANDPKNPYAA Fusgr1 KKFNAPFLKPYWPFFAAGVVIAYGVNSAQNAMMNSAEFKNDPRNPNAK Galma1 RKWPTPILKPLWPFMVAGTVTMYLVAKAQSSGIRSEQWRNDSRNPYAS Ganpr1 ------------------------------------------------ Gloin1 PKYPTQIAKPMSHFFIAASIVWLSLNKVETSMQSNPPYDTDPRNPKAL Hisca1 RKYAAPVARPMLPFFAAGLIILYGVNGFANVMMETPEFKNDPRNPTAK Klula1 KRFPTPVLKPYWPFFAGGLIMFYAISKAADLSANSQEFINDPRNPRFA Lacbi2 RKWPTPIVKPLWPFLIAGSITAYLVGKAQDSGIRSPEWRTDPRNPYAA Lenti61 RKWPTPVAKPLWPFVSASLLTWFLVGKMQDLGVKSEGFRNDPRNPYAA Malgl1 RAYPTPILKPLWPFFASSAIVYYCVSKMQYAGVRSSEYAKDPKNPYLK Mellp23 RAWPTPVWKPMSHFILGGAVTFYLINKVQNSMLASPTYAKDPRNPFGM Mnele ------------------------------------------------ Monbr ------------------------------------------------ Morel2 RAWSTPFLRPMAPFLAGGAVTFYLINAAQEAALKSEPFKSDPRNPKFT Mucci2 ------------------------------------------------ Mydma ------------------------------------------------ Neucr2 KKFPAPVLGPMAPFFAAGLVIAYGINSLQGALMQSDEWKNDPRNIYAK Orpsp11 ------------------------------------------------ Pench1 KKFPGAMAKPMTPFFAAGIIVLYGVNSLQNALSNTAQFKSDPRNPNAK Phybl2 RKWSTPVLRPAGPFIVGGVAVFYLVAKMQDAMINSDEYKNDPRNPAVA Picst3 LRFPTPVFKYYWPYAAGATITYYLVYKGATASMNSDEFINDPRHPRFQ Plicr1 RKWPTPFAKPMWPFFAAAGITTFLVAKGQELGVRSEEFAKDPRNPYAQ Polpo ------------------------------------------------ Pucgr2 RAWPTPVWKPMSHFMIGGAITFYLVNKMQNAMLKSPEYAKDPRNPHAA Punst1 ------------------------------------------------ Rhior3 RKFDVPAFRPVVPFIAGGAVVLFLVSKAQSAMINSDQYRNDPRNPALA Rhoto1 RAWPTPFLRPMWPFMVGAGMTFYLVNAAQNAMLQSDEFKNSPKNPHRI Rozal11 ------------------------------------------------ Sacce1 KRFPTPILKVYWPFFVAGAAVYYGMSKAADLSSNTKEFINDPRNPRFA Salro ------------------------------------------------ Schco3 RKWPTPFLKPMWPFLAAAGLVTYGVSAIQAKAIRSPEYIHDPRNPYAA Schpo1 KRYSTPILKPMLPFFLGGAIVFYGTVKLRDAMMDSAEYRNDPRNP--K Sorma ------------------------------------------------ Sphar ------------------------------------------------ Spipu1 ------------------------------------------------ Sporo1 ------------------------------------------------ Stehi1 FAYATQVVKPMWPFFAASAVTYYLVAQMQDMGVRSEQWKNDPRNPYVA Tapde11 ------------------------------------------------ Thetr ------------------------------------------------ Treme1 ------------------------------------------------ Trire2 KKFPAPFLKPYWPFFAAGLVIAYGANSAQNAMMASDEWKNDPRNPSVK Umbra1 RKFSTPVLRPMAPFFIGTVAIIYLVGKAQTAMIESDDYKNDPRNPA-L Ustma22 RAYPTPVLKPMWPFFVAAGVVFYGINKLQDVAVSTEEASKDPRNPYGQ Walse1 RKYPTPVLKPLAPFIAGSIVVYYGVSKIQDAAVATEPHKSSPQNPYIS Zygro1 KKFPTPLVKPYWPFYLSGAVMFYAIGKAANSSANTPAFINDPRNPRFA [Cluster3590.fasta_al_trimmed; alignment length = 161] Allma1 THVK-DTPLSDLLQEYFLPKIHNLFRRCRGDGNCFYRAVVYAWFERVLRQQLDDALLLANGFQLLVIEDFL-DVAV-DTLLLSRFQADHISNLVVLFRFIASAYLQVHADDYAPFIDMTTFCNQHVEAMGRESDEIQIIALTKQLQ-VNVAVAYLDLLY-R Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 QKML-EEPMREIRREYFVRRIDWLLRRSRGDGDCFYRSIAFAYIEKVLLSTLEATLLRSAGFEPLVYEDFY-EIFR-SVILLEAFQTAEASNMVMYLRLLTSAQIRADADNYAAFLAVREFCESFVEAIGREADHVQVTALARALK-VNVRIAYLDLLY-R Batde5 RQIK-AEDFTALQQEYYVDKIKHLMRNVRKDGNCFYRAFGFRLAELVFLQRAKETLMTTMGYDMSILEDFW-ERFQDVLLVIGAFQTDHISDVVCYLRLITAALLKRDRDIYEAFVSLECFISDCVEPMNVESDQIHIVAMANIFQ-VDIRIANLDLLY-R Botbo1 QNIK-DEPLSTLKTEYFVRKIESLIRRARGDGNCFYTSTAFAWISGMMLLDLEKSSLKAVGFEPIVYEDFY-EVLT-DLILLQQFQNAETVNIVIFLRLLISSYIRLHPDDFEPFLDIKRFCEGWVEAVGREADHPQILALSRALK-LPIHIAYLDLLY-R Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel QQLKTIEPFSILCAEYFLSKATELIRYIRGDGNCFYRAILVGLIEIMLIASSRDWTLVELGFPDWTCTDFC-DFFI-EFLVYTILNDDGSANILMFFRLITSAFLKQNSEEYAPFITVAQYCEQEIEPMWKDADHLAINSLIKAAG-TRVRIEYMDLLY-R Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ERVR-DEPTSVLLDEYFRDKLKDVFRRVRGDGNCFYRAFGFALLQQILVAS----LLVAQGYTEYTIEDFY-DSYV-EVILLAIFRDDPVASVVYYLRLLTAGHFKTNAEFFQGFITVSEFCAREVEVMARECEQVHIVALSAALD-VPVRVVYTDLLY-R Catan2 QAIK-DAPLTDLRQEFFLAKINDLFRRCRGDGNCFYRAFVFAWYERVLHADMAKCVLLANGFQLLVIEDFH-DVAV-DTLLLSRFQSDEVSNIVVLFRFVCSAYLQQHQDEYLPFVTMQGYCAHHVEAMGRDADHVSIIALSKMFA-VNVVVAYLDFLY-R Cioin NNIQ-NEEILTLKSEYYQHKIQELVRKTRGDGNCFFRAFGFGYLEVLLKEAAAGTKLMSLNYPSFTVEDFY-ENFM-SVVLSNSFVDEGLSNFVVYLRLIASCQLQLDADFYQNFISIVEFCK-------------------------------------- CocheC53 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 QNLM-AEPMEVLRAEYFVSQIDYLIWRARGDGDCFYRSLAYAFVLNMLLSQLQSCMLSQAGFEPIAYDMFY-EAFE-AVILLRIFQDANNSNIVAFLRLLTSAQIRLNPDEYAAFIEPTQFCNNHVEPLGKEADHIQVSALADAMQ-IRVQIAYLDLLY-R Copci QQLF-NEPMATLRAEYFVSQIDWLIRRARGDGDCFYRSLAFAYIDQLLLSILESTAILLSGTDEFILEEPY-AMFT-ALILLARFQDQATDPIVYYLRMIASAHLKNNSDQYSGFFTAVDFCSRFVDPVGVEADHVQMLALCRELK-INLNVAYLDLLY-R Croqu1 QNIK-DQSLDALQKEYFVKKIRWLFRRLRGDGNCFYRAFGYGICERLLLERFQALLLDQAGYEKTIYEDFW-EPLQ-TILLMTAFNDQETCATIVFLRLLTAAYLKQHEDDFAPFLSLVEFCQFYVEAVDKDADHLSITALTRCLN-VDLSIAYLDLLY-R CryneH991 ENME-NQPLSVIREEYIVKKLDYLVWRARGDGDCFYRSFILAYLLRILYDAIQRAAMEQCGFQKDIYEEFL-DPLL-ALIIVQALQDPERSNIVVSLRLITSSYIRTHTDLFSPFLSTEEFCRQEVEPCGKEADNAQIMALAEAMN-AGVRVAYLDLLYRR Crypa2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel RDIE-KEPLTCLYAEYFTAKIQDLIRRTRPDGNCFFRAFAYSYLEYLIKKLAEESKLVQLGFPSFTLEDFH-ETFM-EVILHKIFNEQGYSDVVVYLRLITSGKLQEEADFYQNFITIEAFRHLEVEPMYKESDHIHIIALCTALG-AGVRVEYLDLIY-R Enthi ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 QNIL-DEPLSALRTEYFVKQIDYLIRRTRGDGDCFYRSLAFAWVERLMLSMLDEKLLKAAGFQELVYEDFY-DVLI-SLILLEAFQDAEVSNIVVFLRLLTSAVIRTDPISYAPFLTPQEFCERYVEASGKEADHVQITALTKILK-LNVEVAYLDLLY-R Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 QQLL-NDPMSTLRAEYFLKQIDWLVRRTRGDGDCFYRSLGFAYIESTILSVLSSTTLDKAGIEKLVYEDFY-DDFT-SLILLQAFQQAEISNIVIYLRFLTSAQIRLNREAYEGFLDVDSFCANVVQAMGKEADNVEIEALCRALQ-LNVELAYLNLLY-R Ganpr1 NSLR-AEGLEELEKEYFRKKLQELYRSIRKDGNCFYRAFGWRLAELLWKAVLISTLLTSSGYEQVMIEDFY-DTFL-AAMGLEVFQSEYASSTICHLRLCTGAELKRSRDLYEGF-PIDEFVIKSVEPMALEADNLQISALVNAIPLVNIRIANLDLLF-R Gloin1 QSIK--KDIQKLYQEYYRQKIMKLIRRCRGDGNCFYRAFGFAWFERLMLKSLADTLFKEAGYQELVYQDIYEEHIE-KQMLLTIFQTDEISNIVFYLRLITAAYLKLHREEYEPFLGMDQFCSSSVEAMDQEADHIHVMALTKALK-VPVEIAYMSLLY-R Hisca1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 QQLL-SDPMSNLREEYFVNQIDSLVRRTRGDGDCFYRSLAFAYVERILVSALAATSLDKAGIDKIVYEDIY-DEFV-GLILLLAFQSPEMSNVVVYMRFLTSAEIRVHRENYEAFLGVDAFCANIVEPLGKEAGHVEIQALCAALQ-LNVDVAYLNLLY-R Lenti61 QSFP-GDPMLALREEYFVKQIDWLFRRTRGDGDCFYRSLAFAYIENILLSVLEASQLESVGFQRLVFEDFY-DCLA-SLILLEAFNNPEISNIVMYLRLLTSAEIKTNPE-IAAFLDPEGFCNNFVEAVGKEADHVQMNALATALK-VNVNVAYLDLLY-R Malgl1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 QGIK-DQSLEILQNEYYVKKIRWLFRRLRGDGNCFYRAFGYGLCERLLVSRFEGLLLDQAGYEKIIYEDFW-EPFQ-SILLLTAFNDQETCAIIIFLRLLTSAYLKAHEDDFAPFLSLIEFCQFYVEAVDKDADHLSITALTRCLK-VDLSIAYLDLLY-R Mnele DQIS-KDPVENLKSEYFLAKIEHLIRRVRGDGNCFYRAYAYTLFDACKFKKLDTTWLVQLGMPSFTTEDFH-DTFV-ETLLMETFNNDGMSNLVVYVRLLTSGQLQQDSDEYLPFVDMKEFCDKEVMPVDREADHLQIKALTECLS-FPLKLVYVDLLY-R Monbr EDIK-QEGIDVLLAEYFHTKLETLFRRTRGD-----------------LLRLRETMALAAGCPEFTTEDFY-ETVA-DMVLLAAVNDEGLSNLVAYMRIITSAYMQLNADYFQPFITVKEYCSISVDPFGVESEHLQAQALISALR-LGCRITYIDLMF-R Morel2 QAIK-DEDLLELAEEYFKKKIQNLMRRSRGDGNCFYRAFAFAWFERVMVRTIEETLLLAAQFELLAFEDFY-QVTL-ETLLLTAFQNDEISNIVMHFRLVASAFLKTHQDDYAPFLTMDEFCSMHVEAMGRESEEMMLIALTKATH-VSIEVAYLSLLY-R Mucci2 QQIK-DESIHTLKEEFFLKKIENLIRKCRGDGNCFYRALSFAWFESAMLAKLKQTLLESSGFEKLAFEDFY-DVTL-QQYLLVGFQSDEISNIVMHFRFIASAFLRIHAAEYEPFLSIDEFCSMHVEAFGRESDHLQIIALSRALD-VPIQVVYLDLIY-R Mydma RDIE-KECVESLLHDYYQNKLKDLLRRTRGDGNCFYRAFGFKTLEACLCDVATSTKLVALGYSSYTVEDFH-ETFM-DVLIIKVYNEQGYSDFVVFLRLMVSCYLQENEEFYSAFINMKDFCSQEVEPMAKESDHIHIIALTNILK-TTVQVEYMDLLY-R Neucr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 -QLK-KK-----------------FRSVRKDGNCFYRSFAYKYFELV-MRKISGDVLVSANFEKDTIEEFY-EYFM-DSF---SFKDDYISNIVFYLRLICSAELKINHESYEMFL-LESFIAKQVEPLGRDVDNVQIMAIVNALK-VCVNIAYLDLLF-- Pench1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 QQIK-DQPIAQLVQEFFLRKINNLIRRCRGDGNCFFRAFAFAWFESILLAKLKTTLLELGGFQKLAYEDFY-DVTL-EQYLLVNFQSEEISNIVMHLRFVASAYLRIHSAEYEPFLSIDEFCAMHVEAFGRESDHLQIIALTRALD-IPVEVIYLDLIY-R Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 QQML-NDSMDVLRAEYFVAQIDFLIRRTRGDGDCYYRSLAFAYVERLLLSNLNAKMLDAAGFQKMVYEDFY-EYLT-SIILLERFQSAEVSNVVVFLRLLTSAQIRTDPDSYAPFLEPREFCESFVEAVGKEADHVQIIALSRALE-INVHIAYLDLLY-R Polpo ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 QQIK-DE---------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 AALK-DQPLDHLRDEYFVAKIDRLLRRARGDGDCFYRSFIFSLLETYLLSKFSNLLLTACGFEQMVWEDFW-EPLR-DLLLMKAFNDAETNSIIVILRLITSAYLRTHSDEFSPFLTMKDFCEREVEAVSREADHLAITALTRALH-VPLRIAYLDLLY-R Rozal11 QEIK-DAHVSELYDEYFLDKLKQLFRRCRGDGNCFYRAFSYRFFEYFLIKLLENVWLKKIGYQEFAFEDFY-DMTM-EYFLVRIFQEDGTSNIVVFFRLVVSSFLQTHADDYLPFVTMDVFCQAQVEAFGRDADQIHIIALSNALD-VKVKVAYLDLLY-R Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro DAIK-KEDTSTLLAEYFTTKIKSMMRKTRGDGNCFYRAYAYGIAEHFALETLKQTMALAAGYPEFTAEDFY-ETVQ-EQFLHATFNDDGLSNIVAYFRLVTAAHMKTHVDDFLPFLTVAAFCARAVDPFGVDCEHLQIIALTQALG-VAVNIAYLDLLY-R Schco3 QEFL-DSPLAVLRTEYFVQQIDWLIRRTRGDGDCFYRSVAYLFVERLFLSSLEETLLKKAGFEDIVVSGFY-EPLE-ELILLKAFQEPMTSNIVTYLRMLTSAKIRTEPDDFAPFLDPREFCETNVDPTGKEADHVQMTALSQALG-LNIDIAYLDLLY-R Schpo1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ETL----DIRELAKEYYVNKIENLFRRCRRDGNCLYRAVSYALHEKLLQVQIVKSALIEAGFQEYVFEDFY-EATL-ESWVHELFNDSEMSNIGLYYRFMTAVELRTNASEYIHFLTVEKFCNTQVECYGKEADNIQIAALCRYLK-IRLKIVHLDLLY-R Spipu1 RAIKEAEGMQGLEKEFFQRKVKHLMRTVKRDGNCFYRALSFRFCELLWLARAASTIMTEMGYDMSLLIDFW-EPFE-TALLLEIFQTEYVSDIVCYLRLVTAAVLKKYRDLFEAFISLDAFIGSQVEPMNIEADQPHIVAISNALG-ITIRIANLDLLY-R Sporo1 ANLK-EEPLERLLEEYYRTKVKRLIRRSRGDGDCFYRTFIFSLLSSYLLSTFESLLLSACGFEEIVWSDFW-EPLR-DLLLFEAFNDQETNSMIVHLRLLTSAYLRTHSDDFTPFLTMVSFCQFHVEPVNREADHLQIVALTRALG-TPLRIAYLDLLY-R Stehi1 QDAL-DNPMDVLRAEYFVKQIDFLIRRTRGDGDCFYRSLAFAYIERILISTLDSTMLDAAGFEKIVYEDFY-DVFV-GLILLEAFQDSEVSNVVVYLRLLTSAQIRYDPDSYEPFLKPIEFCNTQVEATGKEADHVQVTALSRVLR-INVRVAYLDLLY-R Tapde11 QSIQ-DEPVSTIGHAYVREKIRHLWCRTRGDGNCFYRAFATGLL----TAVLAGSVLDAGGFSPLVYEDFL-DGFT-RLVVLAAMNEPEESNAVVLLRFLTSAYVKAHPEGYAGYLVLTDWCERWIEAMGSEADNLQINALVNALG-VTVQVAHLDVLY-R Thetr ------------------------MRTTRPDGNCFYRGFAFGLCEWLMVSVFEASDLLAAGFDEFI-DDFW-AMTM-APLLLACFRDQERTEIVQFMRFLVSLHLAKNADFFQFFISVDEFRRIEVEAVGRDADHVQITALTAYLD-LAVRVVYLDLLY-R Treme1 EGM--GQPLLVIREEYVVKKLDWLVWRARGDGDCFYRSFTLAYLLRILFESIQRVMMKQVNFDPDLYEEFL-NPLL-EMILIQALQDAERSNIVVALRLITSAYIRTNSQAFEPFLSADDFCRQEVEPCGKEADQVQITALSEALG-VAVRIAYLDLLY-R Trire2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 QKIK-DESIDALEKEFFLEKVQKLLRKCRGDGNCFFRAFAFAWFESLMVEKLKSTLLLSGGFQELAFEDFY-DVTL-NQLLLVNFQTEEISNIVMHLRFVTSAYLKIHSAEYEPFLSIDQFCAQEVEAFGRESDHLQITALTKALD-VPVEVLYLDLIY-R Ustma22 SKLQ-SEPIEVLEKEYFLGKIKWLLRRAKGDGDCFYRAFAFAFIYKIMVKHVESTLLKHAGFDEEVVTDFY-EPLK-NLLLLQAMNEPEQSNIVVYLRLLTSAFLKLNADEYTPFLDMASFCANQVEAIGKEADHVQITALSRALK-VSLDVAYLSMLL-R Walse1 EKIK-EEEMPALLKEYYKNKINNLFRRIRGDGNCFYRAITYAFIE--LKERLENVLLSELGFDSDIMLDFY-QPLL-SILLKVTLNDDEEVSIVVFMRYLTSATIRKNADDFIPFLDIKKFCETYVEAFGKEADHLQMTALGRVLD-LGLKVCYLDLLY-R Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3592.fasta_al_trimmed; alignment length = 211] Allma1 SAHSTEPIT-EDDYFRKATEFRKWLRDDRGQYLDELSSSDARRVF-RKFVRRWNKGELDAEYYRG--T-VALAGAETTRYQWAFVSRIASTARAVSRPY--RAERRTARRDAADRAAELA-PPPSTA-REAMLEKRRATTDFHRSAE-ARSDGGG--KEEFEAA--KRRRDAAAERRETAEPVDDRLAAMRAKEDAAMAMFHQL-AAKFKP Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 SRSRSRELS-KRDLTYYAPMFAMYLDIQKGLIMEDLSEEEIKGRW-KSFIRKWNRGELPEGWY---DP-NTLEKARRNATEQPPVSA-SEAP----IPTIQRKQHRAEARLHMSEMDEIA-PRAEPGTRERRMEKRREAALANRARG-GSPIDLDAIKKAQARE--QRKKNEREIRRARAAEREERLQQYRKKEEETIGWLKTL-AKQRFG Aurde31 ---RSPRIS-ESDYFLKSDEFRIWLKDEKDRYFDELSSDKARKYF-KKFVKAWNRGQLSRRLYAGVDP-T---EVKQTAYKWSFVDRVRAAVAEETLPTAAVAGKKRARAEERDRVEDMVGPRE-VG-REGMLEKKRVKREADKSRDAKDDDGGDSFQAAIARR--DAARKRFSDKRERDMVARERQTAMRDRERATMDMFKQM-AKERFG Batde5 KHEHNKPIS-EEHYFQKAAEFQVWLSE-KGYRFHDLSKSEAQDQF-KKFIRRWNKGKLDDKYYKGIQA-LEVPFAARTGYKWNI-KLVHDSVESMT-----------------------------NG-K---------------------------------------------------------------------------------- Botbo1 SH-REDEID-EKDYFQKNAEFRRWLKDEKGKYFDEITGEKARSYF-RKFVKAWNRGQLSRELYAGIDP-STR-ASTQTGYKWSFASAALESVASATLPSGQAAARKRDREEVKERVEELVGPRE-GG-REGRLENKRVKREADRSRE-KSPGGGDSFKAAIARR--DAARKRFEEKRGGASAPGERISAMKEKEKQTMEMLAKL-AKERFG Botci1 SRSRSRPIT-KNDYETFKPMFASYLDIQKGIFLDELGETEVKGRW-KSFLGKW-------------------------------------------IPNMERFERKIDRKQQKEALDELV-PRAEAGTRERQLEKKKEVNEKMRSRE-KSP-GIEGFKKKKEEF--QRKKNERELRKARQAERDERLQEYKQKEDGTMAMLKAL-AKQNFG Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow TETETAPLS-DTDYFVKHSEFRQWLLEKRKQSFDDLTSTESRKLFTRRFLPAWNGGYLDGKFYAGLTS-RDLASSAKTRHKWGFVPRVSDTVSSLTIPEAVQVEKKSERSANYQRINEQF-PKT-EG-REAAIAERQGRAALKKAAE-GDA-GSDEFKRLQQIK--HQADSRRKEAK--AAVLNEKVAAYQLKEQASMAALRQL-ADMRKQ Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 HRSRSKPLS-KPQYDEYRPLFQSYLDIQKQIQLDDLNEREAKGRW-KSFVSRWNRGDLARSWY---DP-SMLKTAQETVQSYHASSG---------MPRLDRYSRKADRKAQKERLDELV-PRADPGSRERQLEKKRETTSTLQSRE-AKESGIDVYKKKKREQ--ERQKNEREIRRAREAERNERLAERREKESKTMEFLKQI-AQERFG Coere1 SRSPKSPIT-QEDYFRLNAPFRLWLLKEKDKYFDEMSSDKARRYF-ASFVRVWNDGRLRSRYYKQDSELGKLSKSVVTRHNWGFAANIKNSVHKST-----KQERKKSKEREELILDEVA-PKE-TG-REAKM------------------------------------------------------------------------------ Conco1 -----KKIT-EDDYFNKSEEFRYWLRKRYKLYFDELSSKEQREHF-KKFIRKWNERELDDKYYDEANF-KEKDSASNTRYKWGFVKRVKSSVNNQT-----RSADKRLKKHHEMVMEELA-PKP-VG-REAMLEKKKMANAYHKK-E-KSPEEADTFKSALLAE--KKRNERRDRVK----AIQSKVAKYKAQEDESMKLFKEL-AKQRNN Conpu1 SG-RDDPIS-ESDYFLKNTEFRAWLKDEKDRYFDELSGEKARSYF-RKFVKAWNKGKLPDSLYDGSTT-DAPFSANQTASKWSFTSAIHDEVNTATLPSAEDYKRKRDKKAAKDRVEDAIGPKE-VG-REGMLEKKRAQRDNDRARE-KGDEGGDSFRDQIARR--DAARKRFEDKKDRAVA-GERSEALRQKEKATMDMFQQL-AKQRFG Copci SH-RSKPIT-ERDYFQKSDEFRLWLKEEKGKYFDELSGDRARSYF-RKFVKAWNRAKLSRKYYRGIEP-GSMLATTNTSYKWSFATATREEVGAATLPSASAYKRKREKLEAKERIEDMVGPRP-VG-REAMLEKKRARRENDKARE-RGDEGGDSFQAQIARR--DAAKRRQE-AREEIAAMRERTTALREKDKATMEMFQQL-AKQRFG Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 SHSRNKEIS-EEDYFLKSNEFRLWLKEERG--------------------KRWNDGALNRKYYHSPEP---LPATSSTAYRWSFA-SVRADVGRMTLPSASKAERKAAYKEDYRRADEIV-PRS-GG-KEGKMEEKRATNAENRVRE-KDVTDSGSFAAALGRR--DEAEARRRERKSTRSSVNERLQERKQKETATMEMYV--------- Crypa2 HRSRSRQLSYKHDTEVLRPLFAYYLDVQKNLDLDALDVHEQKGRW-KSFVNKWNRAELAEGWY---DP-EMFQRISKELAAS-PPPQ-QQQQQQ--LPSVSRLARKADRVEQRERLDEIL-PRAEAGTRERRLEKKALLNEKMKGRD-GAA-GIEDFKKAAAAQ--QRKKTDRELRRERREEREERLREWREREAEKLKSLKEL-AKARFG Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 SRHRSEPLQ-DSDYYLKNAEFRSWLKEEKDIFFDELSGEKARSYF-RKFVKAWNRGKLPKSYYSHENA-LIQPAASQTAYRWPFASETRHAVETATLPSASSYERKRAREEDKERIEDLVGPKE-RG-REGMLEKKKARREADRARD-AKDDGGDSFQARIAQR--DAARRRFKEKREKESAVKERQEALRAKDKATMDMFKQM-AKERFG Fusgr1 THKTSRPLS-KADLNAFESLLDEYLSVQKQKDMNEMDDREIKGRW-KSFVGKWNRNELAEGWY---DP-ETFARITAAN----PA-E-REEPV---IPTIQRNARKADRTLQKERLDDLV-PRAEAGTRERMLEKKAAVADKMRSRD-KSP-SLDEYKKAKERE--QRRKTEREIRRAKREEMEERKRAYMEREEGTVSMLREL-ARQRFG Galma1 SR-RSSPIS-EADYFQKSDEFRLWLKEEKGKYFDGLSGDRARSYF-RKFVKAWNRGKLADTYYDGIAP-GSMLATTNTSYKWSFASAARAEVGAATMPSAASYKRKRDKLEAKERIEDMVGPKP-VG-REGMLEKKRAKREGDRTRE-KGDEGGDSFRDQLARR--DMSKKRYE-QKEKQNAIRERSSAFREKEKATMDMFQQL-AKQRFG Ganpr1 TREKRERLT-DDDYYRKSAEFRLWL-QKKGKEAD--STKEARKLF-GKFVQKWNDGKLDAIFYGGVTP--AESRKSTGSSGWSFKGRTVSEVQRAT-PKASKAKRRKEARDTEDMLDMVA-PKE-TG-REAMLMKKAARK-----KPTRDDDGGDSFKRSLEME--KRRQERREQVKQLAAVNADKFRSHREKENAIMEQFKKL-AEERFG Gloin1 -----IAIS-VDDYFSKSTEFRTWLREDKDKFFDELSSEQAHRYF-KKFVSAWNKHKLDKKYYDGIRS-SQLTSSETTRYKWKNLKTIKHSVDRQTMPPSLKKELKDFKKTHEATLDELV-PRE-TG-REAIIEKKRAKNAYHRR-E-VSPDGDDDFQSRFAAH--KRARDAREKQKEKAASLQEKAIAYQSKEQNTMDMFKKL-AEEQRK Hisca1 YRSRSRPLS-KHDLQVLEPMFALYLDIQKNIDIADLDEREVKGRW-KSFVGKWNRGELAEGWY---DP-STFQKAQQD-----SAAT-SEPPRERSIPSLQRKEISLARAAHRTQIEEIA-PRAEPGTRERRLEKRREAAAANRAAG-GDD-DLASLKKQREKE--MRKKNEREIRRARAAEREERLKAYRKREEETMSVLREL-AKQRFG Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 SR-RSLPIT-EADYFQKSDEFRLWLKNEKGKYFDGLSGERARNYF-RKFVKAWNRGNLSKNYYVGIDP-MSIPATTNTAYKWSFASAAREQVSSATLPSASAYKRKRDKAEAKERVEDAVGPKE-VG-REGMLEKKRAKRENDRARE-RGDDGGDSFKDQIAKR--DAARKRFENKKEREAATRERANVFKEKEKATMDMFQQL-AKQRFG Lenti61 SH-RRSEIS-ESDYFLKSDEFRVWLKEEKGKYFDELSSDKARKYF-RKFVKAWNRGKLSKSLYAGVDK-QS--ASSQTAYKWSFASAVRDEIDSATMPSASDYQRKREKKEAKERLEDVVGPKE-LG-RAGMLEKKKVQREADRARE-KGDDGGDSFQAQVARR--ESARKRFEDKREKMYAARERADAIRAKDRATMDMFMQM-AKEKFG Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 SSGRRHP---QDDFYLKSAEFRLWLKEEKNKYIDQIDTDKARTYF-AKFARHWNRGKLDSIYYELPIH-LRASTTASSSHTWSFQE-----------PASTRADAKRKRNDERE--EERS-NRA-TG-KDRLLEKKREKREGNTNRE-QEDRTDSSFQAAVRER--DRAAARRNKTNEKQMIQDQKIAVMRSKEDDTMAMLRAL-ADSKFK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr KIYQKERAE-RD----SSAEFRRWLRKEKDKYLEDLDREDSRHYF-RKFIKRWNRGDLSHRYYDGAYSAPAATSDERSSYAWGAKR----------APDREKSERHRRRQDQKAVLDELA-PKE-TG-RDARLAKKAAAREDRRARQ-QSPESSGEF-AHLVRR----ERERRESRAKRRAVADRKLNAYQEKEAARMAEIMAL-AKQVRT Morel2 ERERTQTIS-EDDYFTKSSEFRLWLRQAKKKYFEDLTADDARKYF-RKFVRRWNDFELDESYYKGVRT-SQIPTKSMTKYQWKFAKSIKDSIDTMTMPPPARAEQKRYRKEKETILEELV-PKP-TG-REAMLEKRRAQTAYHRQ-E-RSPDGGDDYKSMLAAE--RRRKEAREARR------------YKEKEAKQMEEFRKLWAQTQAN Mucci2 SHKRRQPIG-EDDYFEKANEFRVWLKESKGKYLDEISSKEARRYF-KKFVKRWNDYELDEKLYKGLNS-AQLESSDTTRYKWSFAKTIRDNVDSMTMP---KHESKRRNERREAMLDEVA-PKE-TG-REAAL------------------------------------------------------------------------------ Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 SRSRSRQLS-RSDYPNFEPLFAQYLDIQKQLYIDDLDDYELRGRW-KSFVKKWNRGELAEGWY---DP-ERFAGAAKEA----VAESTTARPSIETIPSLTRAQRKADRTLQKERLEDLV-PRADAGTRERRLEKRKELNEKLKSRE-PSP-GLEEYKRMMKRE--EVKKTERQLRRARAAEREKRIQEAKEREDRVMEGLKAL-AKARFG Orpsp11 ----------EKDYKNYKKE----------------PDNENKKVF--------------------------------------------------------KQERKKFRKEQRELLDELI-PKP-TG-RKAMLEKRKQITAFHRA---ADKDGDD--------------------------------------------------IKE--- Pench1 SRSRSRELS-GRDLKVYEPMFGMYLDIQKGKYIEDLSEDEVRGRW-KSFTQKWNRGELAEGWY---DP-ATLAKARKSAEEE-PAAA-RQDP----IPTMQRDQHRAEIRAHKSALDEVA-PRAEAGTRERQLEKRREAAASNRARG-GSP-ELSALKREKEKD--QRKKNEREIRRARTAEREERAQAYRQKEQETMSFLQAL-AKQRFG Phybl2 KHHRSKPIT-EEDYFEKATEFRLWLKEEKRKYFNELDSSDSRYYF-KKFVKAWNRFELQEKYYKGLSS-AQLASSDTTRYKWKFASTIRDSVDTMTMPTSPKAESKNLRRKRDSYLDEVA-PKE-TG-REAMLEKRKATNAFHKR-E-RSPDGGDDFQSRLAAE--KQREERRNTRK-RYAPPQDRVAEYKAKENATIEMFRKM-AEEQKR Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 -----KPIS-DTDYFLKSAEFRVWLKDEKGKYFDELSGEKARSYF-RKFVKAWNKGKLPNSLYTGIDP-SSQAANSQTAFKWSFAKAAREAVGAATLPSSSSYKRKRERAEEKERIEDLVGPKP-VG-REGMLEKKRARREGDRARE-KGDDGGDSFKERIAKR--DAARKRFEEKRDRTSGLRERASELREKDKATMDMFQQM-AKQRFG Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 GKKRSQPIS-KDDFFLKSLEFKVWLKNDKNKFIDQLDSHKSKKYF-EKFVRYWNKGKLDEDYYN------RA------------------------TPTPTKNEAKRKRKEDKE--EESA-NRA-TG-KDRLLEKRKEKRDAQGERQ-RDDPSNNSFQEAIRAR--DRAKERRTGKNEKQLVMQEKVAAMKSKEDETMAMFKAL-AASKFG Punst1 GR-DSEPLS-EADYFLKSSEFKVWLKEEKDRYFDELSGEKARSYF-RKFVKAWNRGKLSKSLYLGVEP-T---AQSATAYKWSI--TARTEVESANMPSRESFKRKRDRLEAKERIEEMVGPKE-VG-RAGMLEAKRARRENDRARE-SRDDGGDSFQERIRQR--DAARKRAEERKQHQVETKERSEAIRQKEHDTMEMFKRM-AAERFG Rhior3 SRKSRNSIE-EDDYFEKATEFRLWLKEYKDVYFDELSSKDARRYF-KKFVKKWNRYELD-----GLNS-AQLDSSDSTRYKWSFAKSIRDSVDSMTLP---KYEARRKKDRREAMLDEVA-PRE-IG-REAQLLKKRALNAYHKR-E-RSPDGGDDFQARLAAE--RRRNEIRDARR-----------------------------EQSKR Rhoto1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro K-HKKERLA-EDDYYRKNAEFRHWLKHKKHKTLDDYSYDKRRKYF-KKFVKYWNHGRLSQKYYDGGF-AP-GTGSSSGEYKW-------------------------------KVMDELV-PRE-TG-RDARISKRKGANEARRARA-VSPDD--QFKAYMQRRKYQQERER--------------------------------------- Schco3 SR-RSQPIS-DRDYFLKSDEFRLWLKDEKRKYFDELSGDKARSYF-RKFVKAWNRGKLSREIYAGVDP-SATSASSQTSYKWTFASSVCEEIAAATLPSSTRYKRKRDKLETRDRIENMVGPKE-VG-REGMLEKKRARREEDRARE-RGDEGGDDFQSVLAKR--KAATERYSRARMRDQELREKAGQMKEKEKATMDMFKQM-A-AKFG Schpo1 GK---KDIT-QKEMF--NEIFKEYVKEEKQIDLGTCDQDSVHDLW-RRFVKRWNDGKMKSKWY-------------------SLGK----------RPTLEKSAFKSQAKRETELLDEIL-PKEPAGSKEAMQQKKKEKRAALKHRE-ASDNDRDSFQSRLKQK--KQRSEFRASKRERDQELRNKIEERNKKELETIEKLREL-AKARLQ Sorma AR---RQLS-RSDYANFEPLFAHYLDIQKQLFIDDLDDHELRGRW-KSFVKKWNRGELAEGWY---DP-EQFASLSKDA----AAES-TARPSIEKIPSLTRAQRKADRALQKARLEDLV-PRADAGTRERRLEKRKELNEKLKSRE-PSP-GLEEYKKMMKRE--EVKKTERQLRRAKAAEREERIREAKEREDKVMEGLKAL-AKARFG Sphar GDDRRSEIS-SEDYFAKNNEFRLWLLEEYDIKFDDLDSRKAKKKF-RTFVEDFNDGYLDKKYYDGVHN-NQVQTSSRTSHKWGFAKELRDEIDAATQPSASYRADRYDRRREDDKISQNA-NKP-TSTFEKKMEQKAMRILEKRSRQ-LSPE-----------------NSQREAKRQKNEERQVKLNAYNEKESSTMAMFKEM-AKKFE- Spipu1 SHKRQPAIN-EDDYFVKSTEFQLWLRQEKKLFFNDLSGAETRTYF-DKFVKRWNRGKLQKRYYEGIST-SEVPAAERSRHKWNF-KNARDSVDSLT-----KREQRNMRKDQEMVLEELA-PKA-TG-RDALIEKRRAQNAYHKQ-E-RDVDGGD----SLASY--KRAHERREERKERSTEMAGKVAAYRAKEDATLAMFKQL-AQNRFG Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 SR-RSEPIS-EQDYFLKSAEFRVWLKDEKRKYFDELTGEKARKYF-RKFVKDWNRGKLSKDLYAGIDP-TALPAQSQTAYKWSFASATRSEISALTLPSSSSLKRKRDKREAKERDEDVNGPRE-VG-RERLMEKKREKREGDKAREAREDAGGDSFQDRIRQR--DAARKRFEEKKDRMAETSERVTAIREKDKATMDMFMQM-AKARYG Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 SNEKQNKIS-EEDYFVRSNEFRYWLKHSKGRYLDELSSDTARNYF-GKFVRRWNSGSLEKRFYKVST----FPPGATTNYRWSFANQIKNDVSTLVLPSAAKREKKVGRDKLYERVIEVV-PKN-GG-REGKMEERRATNAANKERE-KDVVENDSFAAALRAR--NIAESRRMDKKERRAADEERLSERRSKEAATMNMFKAI-ARERFG Trire2 KRSLSRHLS-KDDLKAFEPLFGEYLSLQKQRDIAGMDEREIRGRW-KSFVGKWNRGELAEGWY---DP-EMFQRILARH----PT-E-RQQQQQKQIPNKERAARKADRKLQKERLEELV-PRAEAGTRERKLEKRQEVNDKMRQRE-KSP-SLEEYKKAKERE--QRRKSEREIRRARREEIEAKRRAWQEKEDRTVSMLREL-ARQRFG Umbra1 SRRSRKEIS-KDDYFIKAAEFRVWLNEKKHKYFNELSSEDARYYF-GKFVKAWNNFELDQKYYEGITS-AQLSSQDTTRYKWGFSRSIRDSVDTMTLPSSSKREAKGKRQRDEHVLDEIA-PKE-TG-REAQLAKRRAQNAFHKR-E-RSPDGDD--RSSLDHL--KRLEKQKQERFQRTAPIRDKLDTYRAKEDQTMAMFRQM-AEEQKK Ustma22 MRSRSPLLT-REDYYVRSGEFKAWLSL-RGVFLDEVSSSEARRYF-DRFVRRWNAGRLQSEFYSGHI--RSSGSSAGTRHTWGFTKAMRDTVDTMT-----IASMDRQQRERQNALDAIQ-GCA-TG-RDRMLERKRQINADKRAAN-RRDDADHALAETASSR--HLAKQQGAEQR--SAENSQKLAAIKRKDAQTMAMFRAL-AAERFG Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3624.fasta_al_trimmed; alignment length = 42] Allma1 SEENKERFLRVTDFVKKVVHVMYLPTILYIGQPSFARLISPF Ashgo11 SDESKERISRILDLTQTVARYGWLPFILYMGSPNLLNLLSPL Aspfu1 SEETKERISKVIDVSRVAIHYGYLPLIIYLGRPSLFKLFSPL Aurde31 SEETNERILKLVELGRTVMHYGWIPFIIYVGQPSLIKLISPL Batde5 ------------------------------------------ Botbo1 SEETKERIVKAIDIGRVVLHYGWIPFIIYVGQPSLIKLITPL Botci1 ------------------------------------------ Caeel ------------------------------------------ Canalb1 SDESKERIIKLLDYSKTVAHYGFIPFVLYLGKPSILNLLSPF Cangl SDESKERFNKILDLTQRVAHYGWIPFVLYLGKPNLFNLLSPL Capow SEETKDKLRKATDVAKTVVHWGFLPLVIYLGRPSLLTLVSPL Catan2 SEETKDRIVRLTEVVKKIVHVGYIPFILYIGRPALIRLISPF Cioin ------------------------------------------ CocheC53 SEESKERIARIIDVSRVAIHYGYLPLILYLGRPSLIRLFSPL Coere1 NDTVKDIIVKGTTAGKFLVHWGYIPLILFIGKPMLSRIINPM Conco1 REETKDLINKTTELLKTALHWGFIPAILYLGKPSLLKLISPF Conpu1 ------------------------------------------ Copci SEETRERINKVVELSRTVIHYGWIPFIIYVGQPSLIKLISPL Croqu1 SEDNKDRINGACAVLKTIVHWGWVPVILAIGKPSLIK-LRTL CryneH991 SDETKDRYNAVLGIAKTVFSVGWIPLIIYIGQPSLIKLITPL Crypa2 ------------------------------------------ Debha1 SDESKERITKVLEYSKTIAHYGFIPFVLYLGRPSLFNLLSPF Dekbr2 SEESRERLGKVMGTTRDIVHYSWIPFILYLGKPNFVQLLSPF Dicdi ------------------------------------------ Dmel ------------------------------------------ Enthi ------------------------------------------ Falba ------------------------------------------ Fomme1 SEESKERMAKAIDVGHTVLQYGWIPFIIYIGQPSLIKLLSPL Fusgr1 SEESKERIAKLIDVSRVAIHYGYLPLILYLGRPSVIRLLSPL Galma1 SEETKERISKVVEVGRTVLHYGWIPLIIYVGQPSLIKLISPL Ganpr1 EEETRERIMRVFEWGKRAFHVGFIPFILYLGRPSLLRLISPL Gloin1 ------------------------------------------ Hisca1 ------------------------------------------ Klula1 ------------------------------------------ Lacbi2 SEDTKERIAKVVEIGRTVLHYGWIPLIIYVGQPSLIKLISPL Lenti61 SEETKERIIKAVDLARTVVHYGWIPFIIYVGQPSLIKLISPL Malgl1 ------------------------------------------ Mellp23 SEDNKDRINGACAVLKTIVHWTWVPALLAIGKPSLIK-LSPC Mnele ------------------------------------------ Monbr ------------------------------------------ Morel2 NHETKEVILKVTDVVKTVVHFGFIPFVIYLGEPALTSRKTNL Mucci2 NDSTKDTLYKVADVTKTVIHWGFIPFVIYLGRPSVLKLISPL Mydma ------------------------------------------ Neucr2 SEESKERIGKLIDISRVVVHYGYLPLILYLGRPSIIRLLSPL Orpsp11 ------------------------------------------ Pench1 SEETKERVSKVIDISRVAIHYGYLPLIVYLGKPTLFRLFSPL Phybl2 NDSTKETIMKVFDVSKQIVHWGFIPFVIYLGRPSLLKLISPL Picst3 SDESKERIAKILEYSKTIAHYGFIPFVLYLGKPSLFNLLSPF Plicr1 SEETKERITKAVDIGRTVLHYAWIPLIIYVGQPSLIKLISPL Polpo ------------------------------------------ Pucgr2 NEDTKERVNQVTAAIKTILHWTWIPIVLTIGKPSLIKTPRSL Punst1 SEETKERIIKAVELGKTVVHYGWIPFIIYVGQPSLIKLISPL Rhior3 NDSTKDTLYKVADVTKTVIHWGFIPFVIYLGRPSILSVYNKG Rhoto1 SDDNKERISKAIEVAKTIVHYGWIPTILFVARPPLMRLISPL Rozal11 ------------------------------------------ Sacce1 SDESKERISKILTLTHNVAHYGWIPFVLYLGRPNFLNLLSPL Salro EPKTAEKVQAAIEVAKTVFKWTYIPALIYFGRPTLADVFTLG Schco3 SEDTKERIAKFIEIGRTILHYGWVPAVIYIGQPSLIKLISPL Schpo1 SEESKERLVKVFNIGKTVTHYGWIPLILWLGRSTFSEFFTN- Sorma ------------------------------------------ Sphar ------------------------------------------ Spipu1 ------------------------------------------ Sporo1 ------------------------------------------ Stehi1 -----------IDCEQTVLHYGWIPFIIYVGQPSLIKVYSSF Tapde11 ------------------------------------------ Thetr ESSTALKILKVVDTAMTVLHYGFIPLIIGLGRPGLHKVFLPF Treme1 ------------------------------------------ Trire2 ------------------------------------------ Umbra1 ADAFIYITSKVVDVSKQIVHWGFIPFVIYLGRPSLLKLISPL Ustma22 SEDTKERIIKAVDVSKTLLHYGWVPFVLYIGQPSLIKLISPL Walse1 SDDNKERVTKAVEVAKVAAHWGWVPFVIYVGKPSLIKLLSPL Zygro1 SDESKERISKILSMSHTVVHYGWMPFILYLGRPNILNLLSPL [Cluster3640.fasta_al_trimmed; alignment length = 55] Allma1 IVLA-VPKSRTTHGKKRMRM-SNKGLKNREDIVPCPACKAPKLLHHACPACLAKI Ashgo11 ------------------------------------------------------- Aspfu1 ------------------------------------------------------- Aurde31 FVLA-VPKKKVSHSRKSMRE-ANKGLRDKLNLVACPACGMPKLAHNICPSCYQQL Batde5 FLLA-TPKKRTTHRTKRIKL-APKWLKPMKNIQQCPICGADKLIHHICPKCLKTL Botbo1 FLLA-VPKKKVSHSRKSMRS-ANKGLKDKTNIVNCAGCGSPKLAHNICPACYSAV Botci1 ILKA-VPKKKTSHMKKRHRQMAGKGLQDVTNLNRCSACGHIKRAHLLCPYCVAEI Caeel ------------------------------------------------------- Canalb1 ------------------------------------------------------- Cangl ------------------------------------------------------- Capow FLWA-LPKRKTTPARKARRS-THKGLEPVAQITTCMTCGRPKHTHMLCGACFRTT Catan2 FLMA-VPKSRTTHGKKRMRM-SNKGLKNREDIVPCPVCHGPKLLHHVCPGCLAKL Cioin ------------------------------------------------------- CocheC53 ILNA-VPKKKTSYRKKRQRFMAGKGLKDITSLNRCSACGRVKRLHILCPYCVDAI Coere1 ILRA-VPKQRTSHSKKRKRM-ANKGLKDRQDLSPCPGCGRPKRAAHICRNCYGSI Conco1 ILKA-VPKKKTTYGKKRMRA-SGKALKKIQNIVPCTSCGEPKLMHHLCQNCYKDL Conpu1 IILA-VPKKKVSHSRKRMRS-ANKGLKDKHNIVNCPACGEAKLAHHMCGNCMSII Copci VVLA-VPKKKVSHSRKAMRS-SNKGLKDKQNIVACPGCGSPKLSHHYCETCYSEL Croqu1 ILKA-VPKKKVSHSRKRMRS-AHKGLKPDLGLSNCSGCGQSKRKHHLCLNCYAEK CryneH991 FLWASVPKKKVSHSRKNMRA-ANKGLKNKTNLSLCPACGSIKLTHHVCPTCYSQI Crypa2 LLKA-VPKKKVSHSKKRHRQMAGKALKDVTSLCRCSVCGHPKRMHVLCPNC---- Debha1 ------------------------------------------------------- Dekbr2 ------------------------------------------------------- Dicdi ------------------------------------------------------- Dmel ------------------------------------------------------- Enthi ------------------------------------------------------- Falba VLFA-VPKKKVSRPMRRNRI-VHKQLQKITNVEDCPSCGSPRLLQNLCRNCRTIV Fomme1 ILWA-VPKKKVSHSRKAMRS-AHKGLKDKSNIVSCPGCGSAKLAHNICPKCYSQI Fusgr1 ------------------------------------------------------- Galma1 FLLA-VPKSKTSHSRKAMRS-ANKGLKDKRNITNCAGCGSVKLAHHICPNCYSAV Ganpr1 ------------------------------------------------------- Gloin1 ILWA-VPKKKTSHSKKRMRS-ANKGLKDKTNIVNCPGCGQKHLTHHLCFNCY--- Hisca1 ------------------------------------------------------- Klula1 ------------------------------------------------------- Lacbi2 FVLA-VPKSKTSHSRKAMRS-ANKGLKDKHNITSCPGCGSPKLAHHLCSNCYGSI Lenti61 WLLA-VPKKKTSHSRKAMRS-ANKGLKDKQNLVHCPACGSPKLAHNLCPTCYREL Malgl1 LVLA-APKKKVSHSRKAMRA-ANKGLKDRVGT----------------------- Mellp23 ILKA-VPKKKVSHSRKRMRS-AHKGIKPDLGLSSCSGCGQSKRKHHLCLECYADK Mnele ------------------------------------------------------- Monbr ------------------------------------------------------- Morel2 IVWASVPKSKTSHSKKRMRQ-ATKGLKEQRNIVECPGCGQPKLMHHLCQHCYRDM Mucci2 ILWA-APKKKTSHSKKRMRA-SNKGLQQKENVTTCPACGSNKLLHHLCGNCYSDI Mydma FLWA-APKKRRSISKRRYLR-KFRELKLRDDIEDCVVCGNKKLMGKLCQNCFQWT Neucr2 ILRA-VPKKKTSHMKKRHRQMAGKALKDVTHLNRCPACGNLKRMHHLCSTCLGKL Orpsp11 ------------------------------------------------------- Pench1 VLRA-VPKKKTSHMKKRHRQMAGKALKDVKSLNKCPGCGQIKRAHLLCPNCVKDI Phybl2 FLWA-APKKKTSHSKKRMRA-SNKGLPTKENVVGCPGCGNSKLLHHLCKHCYGDI Picst3 ------------------------------------------------------- Plicr1 FLLA-VPKKKVSHSRKSMRS-ANKGLKDKQNIVNCPACGAPKEAHHLCKECFGAI Polpo ------------------------------------------------------- Pucgr2 LLKA-VPKKKVSHSRKRMRS-AHKGIQPNLSLGVCPACGEPKRQHFLCLHCYADK Punst1 IVLA-VPKKKVSHSRKSMRS-ANKGLKDKHNLVHCPACGSPKLAHHLCQQCYSEL Rhior3 FLWA-APKKKTSHSKKRMRM-SNKGLQQKENITKCPACGSNKMMHHLCPNCYSDI Rhoto1 ILWA-APKSRTTHSAKRMRS-AHKGLKEKQNLVSCPGCGAPKLAHHICRECYASF Rozal11 ------------------------------------------------------- Sacce1 ------------------------------------------------------- Salro VLMA-VPKRRTSHSKKRMRM-TTKYLKNKSHYQKCKHCGELCMRHHICPGCIELW Schco3 IVLA-VPKKKTSHSKKRMRA-AGKGLKDKQNIVSCPGCGSPKLAHHLCGKCYGFL Schpo1 ILLA-VPKKKTSYTKKRSRLLSGKALKDKT-VNRCPICGSFKLAHHLCSHCFRNI Sorma ILRA-VPKKKTSHMKKRHRQMAGKALKDVTHLNRCPACGGLKRMHHLCSNCLGKL Sphar MLMA-VPKRKTTPSRRRVRQ-HDKFPQNIQNITTCHKCGGAKLLHALCWACTKKI Spipu1 ------------------------------------------------------- Sporo1 ------------------------------------------------------- Stehi1 WVLA-VPKKKISHSRKAMRS-ANKGLKDKQNLVNCPACGSAKLAHHLCPNCYSGL Tapde11 ------------------------------------------------------- Thetr ------------------------------------------------------- Treme1 FLLT-APKKKTSHSRKSMRS-ANKGLKNRTNFSHCAACGQVKLMHNVCPYCYSQI Trire2 VLRA-VPKNKVSHSKKRSRQMAGKALKDVNHLCKCPGCGEVKRTHRLCQNCLEEM Umbra1 ILWA-VPKKKTSHSKKRMRA-SNKGLKQAENITSCPACGNAKLMHHVCRHCYQEI Ustma22 ILRA-VPKKKVSHSRKSMRA-ANKGLKDRTDLVHCSSCGKPKLHHHICASCYFEL Walse1 ILRA-VPKKKVSHSRKAMRS-ANKGLRDKNNLVHCPASGLPKPAHHLSQELYSQL Zygro1 ------------------------------------------------------- [Cluster3642.fasta_al_trimmed; alignment length = 327] Allma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ERDTWSLIQALLAVRDWAEGTAMDPDAVNRDESYERALSQSLYIRAGQLDDAMTFCRDHPWRAAILRGGNKRRKLWKDACATAARATT-LNQPTRSLYAALAPQRRTLLA--QCKT-WEDHLWAHVTVEERLDGELSELSGV-SYHYSQLQVITDKIDELISQFVVRFFAHYCLF--RRHIILEAYITFLEAASEDLVALYSASLSAAIERYASFLAALAALKRAEEHGLDTVQVAIAVALLTTAVEWLVF-HEDTLPRALNQVNNVIRYFLAMGHIVAARWFLETWKWIREYSNRVRQIYIPELVIRLHAVLMNSRNIRAALE--L Batde5 EADTWALVCALIIVKQWLESIALDPDAPSRDQSYETELLRTIYLRRGRLADAFHLCRAQSWRIASMGGGNENRVLWKAICYQIALDDN-TQLYERAIYAVLAGDIKNALP--ACHT-WEDHIWVRYHAESLTSKIFTELSKS-EFHIIQAHLILDSLDMLFASLVLRFTAHLILL--LRDFLLSRYIHMLHVAGKDLIAMYVAYLEMQVDCYSSFLQDVALVTAGIDCMLDMPRICRMTVLLIRALEWLDM-DDMQLEDRLDHANLLARHFLIQGHVQSVQSLVECLSWQGKVKSLIKGIYVPELVMWMHQILIQTHNLEQSLE--L Botbo1 ERDTWALVAPLSIVRAWLHDTALDPDAASRDAEFDKVLNQAIHIRAGNLYGALEICHAQPWRSALLRGGNRRRRLWRETCARGANSAT-LHSTHRTLLAALSPSGRTLQP--ALRT-FEDHLWARVSAEERFDAALEEMEHV-KIRLAQMFLILDRTDTLFTLLVIQFYAHLCLF--LRDVVLQAYVMILEQEKRELVALYIGALSNALDRYAEFLADLVALNRAKDHGLDVIAVAEKTGVLIRSVEWLTV-HQETYEQALTQANALLRYLLGHGRILAAQKFFTVWDWKKAYAAAIRQIYVPELVLRLHQELFMSRNLKLVME--F Botci1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel EAVQIASVLSIYALLLWSEKAILDPDAPGT--EDQA--LEQMLIRSGETSKAANLAIDMGAIGAQLQLYQMTQKLIE-------QSQG---SEDDALISAIRGNIQPMLK--AGKS-VIEKVWAYANSTQETISILDELRSE--Y--ILLRVIDDMLNDDIEDLQVNMLAHLVAVSYASAVIILGFDDLRARSGTKMAAFYSRFL--------------EIVE-------TMKAVDSDEETKVVTLEWLLIGGEETALAALEECNRLV------RKVMLSCSFVDVNNWEASLRVRIRNLFLPQFFILLAQAAVRLDSFNNDLG--L Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ERSAWRLARFLLTILHWLESLALDPDGPLRDIDRERTLLRLVLIRSGRISDAQHLCQEHAWRAATLGSDG--RLVWIHACRMLASDTR-ISSLERAVYASLVGDVSHTLP--ECTS-WEDWLWAYFRGFDRIELHFAAATNA-DFHSAIAAMVLNDADALLSTLVIRFAIHLALH--LR-GMLAVYVEFLIDTHRDQVALYVSFISLQTALYAAFLQPFQYLAQGDQHGLDVARIAKAVVAAVRSRPGSAM-RPIESASAAMDTSAGPLPLVAATHFKSKRALVAAYEWQQLIIELLRQKFIPALAFLLHRVLHDTEQTGHAMQ--V Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin EKQTWRLISALQIVIDWLEQNAMDPDAPTRDREDEKQLLKIIFIRAGKIEEAEDLCVTQPWRAATLEGGNPHRDLWKLACWTLSSDET-NNAHERAIYGALCGNMDAMLS--VSSS-WDDHLWAHYKTDMATERVFNKIENS-NYHFIQRCIILNDMEAMMDKCLLRFLVHIILF--LRDKTIEAYVRKLIADGRHLVATYTAALELQIINYSAFLEAIEYLELALEAGLEIPAITKRVVRKIDSIEWLVF-DPSQRCEALKQCNAVMRQFLASRKHEAAKAYLGAHTWDDKLRSLLRRVCIPYLSNLLLTVLVDTGRYKECGQ--L CocheC53 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 ESNTWDLLERLVEVRRWLEETAVDPDATSRDAEYETSLLRTLYVRRGRVGNAMDLCVEEPWRAASLKGGNINRALWKHACAALAHDEN-NDIYERALYAALSGRLDEAVL--VCGT-WEDFLWAYVNSESYIDQVFGTIASH-DFRMLQKALITDSFDEYLTEFLLRFVVHAALC--LRSILLETYIGCL-AKGHELVAAYVSHMEEQTESYAQFLQHVQLLKLAENHRLDIDAISKRTTGQVRAIEWITS-STRLYEHALVEVCKLARQFLLAGRTNAAFSLCDAYAWKENIAQILRELYIPETVFRLHSILFDTRNLKRSLD--L Conco1 ELNTWKLVKELAAIRAWLENIALDLDCEFRAKQRDILLSRAIHFRKGSIDDAIDVAIQEPWRVATFNGGNFNRTQFKKRMEKLSSYPK-FNPYERALYALLSGNLNQLIP--ICTT-FEDYLWAMISCEFYIESTLNQMLKQCKFNIIQDFLIRGEFEQLFQYALKRFFAHLYIY--LTSTCLITYINELQS---RMVALYCSKLKDQTLAYSSFLIKLEFIRYASGYGLSVKDIIMQTALLVDSISWVVN-NPSTYLESAQLANKIIRKFLIRGKLYQATQLVNCFRWKKELENLLRRLYIPELLIQIHSAYLLTSNPQRSLEQLL Conpu1 EANTWGLLQAVIVVREWLHETAMDPDAANRDSRFEKSLAQALFVRAGRLEDAVEICRKQPWRAASIRGGNRHRRQWKRACARAANNTS-LSDSERALYAALAPCPETLKS--ACRT-WEDHLWAQVCIEEKQSQSLEGLSGA-QFHVCQLAIIMDRIHPLLEGFMTRFFAHLALF--LQQVVLEAYLQLLESAGQELIAMYAGALENAVERYAMFLTSLMALTRAREHGLDMSRVAIVTALLLRSIEWTTF-MDNTYKTALEQATVILRYFLGSGRIKLARQFFTIWEWLKDYKGLIRQIYVPELIIRVHALLFTSRNLRRCLM--L Copci EANTWGLLQLVVVVREWLQDTALDPDAPNRDASYERSLLQALCVRAGRLDEAVDICRKQPWRAASILGGNKRRKLWKDTCTHAALNTS-LSDQERILYAALAPSPATLKA--ACKT-WEDHLWVQTSIEEKASLSLETLKDV-AYHFSQLHIILDRTDALLNSFLCRFFAHFCLF--LQQTILESYLQVLEEAGQELIAMYAGALDNAVERYALFLVSLLALTRARDHGLDMDRVAIVTAFLLRSIEWTTF-SDTTYPVALEQTNVILRYLLGMGRVQVARQFFVIWEWVNEYRNLIRQIYIPELIIRLHFLLFESRNLKRALQ--L Croqu1 ERNTWQLVQMLSTIRDWLYTCPLDPDAPLRDEEYDRAMIRTLYVRAGEIDLATDFCRQHHWRAASLSGGCLNRKLWKSICLQISLNQS-LSTYEQALYGALSGQISSVLP--VCYT-WEDHIWCHINSENQVDKAFDKVLRS-EFHVAQMWLAIDKINDLFTTFLLRFFAHLILF--LRNAIIRAYVQVLEIEKKDLIAFYVAELESGVETYAKYLISLTALLRAMEHGLDLSRVACTAVELIRSLEWLTI-DQTTYFDALVQANSLIRYFLSSGHPNAAQDFFNCLEYTQVLDDLIRKIYIPELVFRLHGALVDSSNLRRALD--L CryneH991 EHRAWQLIRAVATLVEHLQTRPLDPDFTIRDQTYQLPLLETLLVRYGELESAIKVCEQEPWRGASLMGGNRYRALWKKSCRTIAKNHT-LLPAERHLYAAMISDLPTLLP--A----------------SRLEKVFASMKSL-QYHVAQQMILLDRTGALFHGFLLRFFTHLALI--LRNAIIQAYLQILEREGNKLVAMYAACLGSGEESYARFLWSMEALLRAKKHNLDVALIARETVVLIRSIEWLTI-LPETADDALVRSCQLVRYFLSKGQANAASRLFSLFSWKQDLEAGIRLIFIPDLILRLHNALTEQSFLQRALE--L Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi EKDTWSILKKLLILLEWLEEMSLDPDAMSRDEKNQSRFLKTVFLRAGDRVGAAEYCTNQFWRAQTLIGGNPYFNLWKSNCLNISKNSN--DQYERAIYGLLCGNLEATLP--IQKN-WYDYFWCYLRVDESLYRILEILKNNTSYHQIQELIIADDYSILFNSLFNRFAVLLILF--FRNIVINEYVQHLINSQQELVALYTSLLSLQVDVYSRFLVNIQLLVLAEKFGLNTQEIAQSVVVKINSIQWLCF-EKQLLIKAILQSNLLLRDFISLNKYGAAENYITANIWNQNNINFIRKKCIPSLFKSLYTILVGIGSIQKSSQ--L Dmel EINTWRLLHALQLVVDWLEA-CLDPDAPVRDEEDNLRLSRAILIRAGRVDDGLKLCKHQTWRAAILEGGNPRRDIWKRCAWMLADSKN-YDEYSRATAGVFSGHLGSLKT--LLHSNWHDLLWAHLKVDIRVESIFEELNVA-KLGIIQRHLILDTCGELIQHMQLRFMAHIVLF--LREKIVAAYVEALIARGEQLIAYYTASLPLQVQLYSRFLEQVLAVDAALQAGLDVEQITRVTVRKISALEWLIH-LPEQRGELLWQANAMIRTYLASSKVECMKAYLSGVDWEHKVKEQLRSICIPEIALFLNEVM-FKSDFAGCVR--L Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ESNTWDLVQLLVIVREWLHDNAMDPDAINRDANYEKALAQALYVRAGRLDEAVDLCRRRPWRAASIRGGNKRRNLWKATVTRAALNPL-LSEPDRALHAALAPSPATLKS--ACRT-WHDHLWAQVSIEGKQVDALKALSNV-GFHVSQLHIILNQTDKLLSDFLTRFFAHLCLF--LRQAILEVYLQVLEEAGQEHIALYASALENAVERYALFLTSLQTLRRAERHGLDIIRVAQVTAFLIRSIEWTTF-QEQTYRDALEQANAIFRYFLGCGKVQAAFQFFAIWDWLASYSGLIRRIYIPDLVIRLHMLLVESGNLKHTFT--L Fusgr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 EENTWALLQAVIVVREWLQETAMDPDAVNRDASYEKNLLQALYVRAGRIDDAVEVCRRQPWRAASIRGGNSKRTLWKSTCIRAALSPT-LSDQERLLYASIAPSSQTLKT--ASRT-WEDHLWAEISVEEKASRSLDSLKSV-AFHFSQLYIILDRTDTLLKVFMCRFFAHLCLF--LQQTILESYLGVLEEAGQDLIALYAGALDNAVQRYAAFLVSLLALTRASDHGLDVEQVAKTAAFLLRSIEWTTF-LPETYPIALEQATVILRYFLGAGRIQAARQFFVIWEWLAEYRGLIRQIFVPELILRLHYLLFSSRNLKRALE--L Ganpr1 ERNTWNLVARLIAVLQWLQHTALDPDAPLRDATLDTKMNVALMVRRGVLDQVDDMCSAASWRAGSLAGGNRNRDLWKAMCWEVAQEST-YDRYERAVYASMCGDVQNILP--VCET-WEDHLWAYYTSEMTATQIFDRVKRHFAWYRIQECIILNRLPELFSEIMLRFLSHLALI--VRENVILIYAGVMIKANKVLVASYASQLPLQRRIYPTLLESIAYLELAAKYGMDVKNLAQTVVSVVRLLEWLDW-KAGWWAEKIEAINYLMRYWLLQGNLPATKILVEGLVWKAEVVQSLRDAYLPESILWLLEVLYEVRALEEANK--L Gloin1 ERNTWNLLKLLWIVRQWLWKIALDPDGVHRDQEHEKELARSIYLRRGQVDDAMDISDKHFWRTASMSGGNINRHIWRTTCYHCANQVN-VYIYDRAIYGVLSGDYENIIP--VCRT-WEDHIWAYYHSECQQDEIFEMVESK-RFHIIQKLIILNDSKELVKQLFLRLATHLILY--LRDHIIKLYTELLIEYRQKLIALYASKLDTSIEIYALFLKDVKLFILAEQYGLNVIAIARKTFIQIRALEWLTF-NKEQHREALKLGNTLCRRFLASGKMNVAYNMIEYYNWNKSIKEVVMDIYIPNAVLRHHTALYETRNLEKSFN--L Hisca1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 EQNTWGLLQAVIVIREWLHETAMDPDAPNRDASYERNLLQALYIRGGRFDDAVELCRKQPWRAASIRGGNQNRHLWKTACTRAALSPA-LSDQERILYAALAPSPQTLKL--ACRT-WEDHLWAQVSIEEKESQSLDSLKSI-AFHFSQLLIILNRTNTLLDSFMCRFFAHFCLF--LQQVILESYLQVLEDAGQDLIAMYASALENAIERYALFLVSLLALTRARDHGLDPARVAVVTAFLLRSIEWTIF-QDTTYNTALEQANVILRYFLGTGRVQAARQFFVIWEWLDDYRSLIRQIYIPELIIRLHFLLFDSRNLKRALQ--L Lenti61 ESDTWALLQALVVVREWLHDSALDPDATSRDAAYEKTVLQALHVRAGQLDEAVDLCRKQPWRAASIRGGNVRRRLWKSTCEGIALNQA-LPPPERALYAALAPSTATLKA--HCRT-WEDHLWALVSVEERLSATLGALSNV-QYHVSQLHIILDRTDELLESFMTRFFAHLCLF--LQQIILEAYLQVLENAGQDLIAMYAGALDNAVERYALFLTSLLALTRAKDHGLDVERVAVVTALLLRSIEWTTF-FESTYDTALEQANVILRYFLGRGRIQLARQFFGVWEWLNDYKGLIRQIYIPELIIRLHSIMVNSRNIKNALS--L Malgl1 ----------------------LDPDASVRDMHYEKALIRSLYVRAGELDMALDLCVQQSWRAASLRGGNRTRSIWRRIAWKAALNVS-LDPYERALYGALCGELSSVLA--VSET-WEERLWGYINAEQQL--IFEQLAHA-SYHIVQRAVITDSVPDLLSRVLVRFFAHLALF--CHAPILNAYVGVLQRAGQELVALYASSLENAHEVYADFLCTLHALVQVKPHGMDPAIVARKTVRLILSIDWLTF-FDATYADAIVQANTIMRVFLTTGRLHAARIYFDVLNWASALRSAIRRKYIPEIVVSLHLMLVDTSNLAHALA--L Mellp23 ERNTWQLVQMLSTIRDWLYTCPLDPDAPLRDEEYDRAMLRTLYVRAGEIGLALDFCRQHPWRAASLSGGCLNRKLWKSICLQISLNQS-LSTYEQALYGALSGQISSVLP--VCYS-WEDHIWCYINSEIQVDRAFDRVLRS-EFHVAQMWLAIDKINDLFTTFLIRFFAHLILF--LKNAIIRSYVQVLEIEKKDLIAFYVAELESGVETYAKYLISLTALLRAMEHGLDLSRVACTAVELIRSLEWLTI-DRVTYFDALVQANSLIRYFLASGHPNAAQDFFHCLEYKDVFEGLIRKIYIPELVFRLHGVLVDSSNLRRTLD--L Mnele ERYTWKLLGAIQVVLDWLESNAMDPDAPSRDAEDQSRLVKHMLVRAGQVDKAQQLCIEQCWRAAVIEGGNITRALWKNCCWDFCNSSG-VSTEEKALYGALSGNLQAILP--ACTN-FHDVLWAHFKTDQEVEEVIDTM-GK--YNKLQLQLICGNLSGIL---QCRFLCHLLLI--LETKYILALQN-------EEVVFYASLLELQISLLSEVLAHVQCVQYAAVYSVPIEEVSMRIYRVVGAISWLLL-SETQRRSALREANRLIRMFLGARKHAPAQAYLDTHQWSAH----------------------RPS---------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 ESNTWLLLETLSAVKSWLEVIAQDPDATTRNQRVEHDLLLAVYIRRGQVQKAKDACENEPWRAESISGGNKTRGLWKGTCYALAKEST-AEQYERAIYGALCGDIPSVLP--VCSS-WEDHAWVRYNAESMIENIFDSIDNS-DFKTIQTSIILGQTDQMLTNMMLRFMAHFVLL--LRDFFIKSYVDLLISKQLDIAPLYASFLKLQIETCSSYLKTIGYLANIRKYGLDLHAILTATVAQIKSLEWLTF-ETPQYLECLFRSNHLIRQYLADGRLNAAGDLFAARRWDVEMKELLRQIYLSEIALNLHEVYFQSRNLEKSVE--M Mucci2 ENATWRLLSLLAVLKQWVSQIQLDRREPPRKQQDDEAICKQHKLRSNDLTPITAL---SVSLNYMVNG----RRVWKKAVSHALKQEP-ADRYKSALLHVLAGTSKELYDTTACNT-WEDVIWAYLN-------DIAKIASS-KFHHILSAILSDQPQRIIHDITLRFLSTFILY--GRAALLSAYSEINAGPAIIVIAAYAAKQDLQTRIYSNFLQNFILIQLGKEYGLDMPTILQHTYIFVQAIKWLTL-DESMCVEAFEAINQTIRSLLGVYKIYLISCLVSVLVWTDQVQTKLRQLYIPDLVIRYHHVLYSTLQCKELSQ--L Mydma ECNTWRLIGSLQIIVDWLEKNMIDPDAPIRDQQDEEQLLQYMFIRAGKLEEAQKLCCDHYWRAASLDGGNPNRDLWKINCWAMSEEKS-FNIYEKAIYAALSGNLNQLLP--ACLS-WEDCLWAYFKVDIRVEEI-DHIRSH-PYRILQTNIILNDINDFLKEMLIRFLAHLVLF--LQNEILHSYVKVLI-DIKNLVATYTARLDMQVKVYANFLQDISYLNLADEAGLDLGLITKCIVQKITSIDWLIF-DPAQRAEALKQANAIIRGFLAEKKHDSSKAYLNAHDWLKTLESHLRQLCIPYLSFLLMSVL-QSSKHRECFQ--L Neucr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 -----------------------------------------------------------------------------------------------------------ALA--VCKT-WEDYLWVYYNSENELSKIFDSLLKN-EFHYIQKMIILNKYDEMIIHFLLRFFVHFILL--LKEYIIIAY------------------------------------------------------------------------------------------INSL----------------------------------------------- Pench1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 EVIAWNLLDSFLYIKSWLEETTIKAKEQARDRQDLEAYYITILIRRGQFDELTSLASQKVFFIHFAD-KAEKRKMWKKMCDDQLKDKN-LGPYGKAVFSAITGRTEHLLP--VCET-WEDVIWSYNNAQATIEKEIASLANG-KFHHAQTIFLSSKPLELIDCLFLRVAASFALY--VQNSLLECYA---TKLADDDMAMYTSTLDLQTSFMARFFKNFELVKIARKYRVDISSVLECIFICLKAVGWLSM-DNAMANNLIERINGVLRYLLATRQIGLARSVIEILRAREDFRNLLRKVYITQLVFYLHDLYFDTSHCKDSLN--L Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 EQDTWSLLQALIVVREWLHDTAMDPDAVNRDSNYEKSLAQALHVRAGRLEDAVELCRRQPWRAASIRGGNRRRKLWKSMCTRAALNTN-LSDPERVLYAALAPTPQTLKS--ACRT-WEDHLWAQISVEEKQTATLESLESV-QFHVSQLHIILDRTDTLLGVFMTRFFAHLCLF--LQQVILEAYLRVLELAGQDLIAMYAGALDNAVDRYAMFLTSLLALTRARDHGLDPDRVAVATALLIRSIEWTTF-TDTTYDTALEQANVILRYFLASGRVRIARQFFAIWEWLKDYRGLVRQMYIPELIIRLHALLYISRNLKHALE--L Polpo EKNTWDILCRLIIVLNWLEEMALDPDAQQRDEKDDHQFLSTLLLRVGNRELAIQFCQLQHWRAQTLIGGNPYRNLWRQSCLTLSNNAS--DEYERAIYGVLAANVGNALP--VCKN-WYDYLWVYVRVDIKLNEILHILRTN-SYNIIQDRLISDDYQTLLQSLFLRLSIGLVLF--YRNVIIHSYIQYLIDTQKELVALYTSFLVQRTKLYSKFLEGIRCLGLAERYNLDTELITETVVAKIDAIGWLCF-NPQQRIEAILKSNLLIREFVENNKLDAASQYLEATRWSQNNMLYLRVSCIPPLFFSLHQLLVGTEQYKKSSR--I Pucgr2 ERNTWQLVQMLSTFRDWLYTCPMDPDAPLRDQEYDRAMVKTLYIRAGEMGLALDFCRQHPWRAASLAGGCLNRKLWKSMCLHMSSNKS-LPTYEQALYGALAGETSSVLP--VCYT-WEDHIWCHINAENQVDQAFDKILRS-EFHVAQMWLAIDKINDLFTSFLLRFFSHLILF--LRNAILRGYVQVLEMENKNLIAFYVAELESGVETYAKYLISLVALLRALEHGLDISRVACTAVELIRSLEWLII-DPATYLEALIQANSLIRYFLTAGHPNAARDFFNCLEFTEALEEMIRNIYIPELVFRLHGALAESGNLRRALD--L Punst1 ESNTWALLQLLVQVREWLQDTAMDPDAGNRDANYDKALAQALCLRGGRLEDAVDLCRRQPWRAGTIRGGNRRRRLWKSTCTRAALNTA-LPDQERVLYAALAPSPQTLKI--ACRT-WEDYLWAQVSIEEKQSATLDALRSV-SLHISQLHIILDRTDDLLEGFLSRFFAHLALF--LRQVILESYLRVLEAAGQDLIAMYAGALDNAVERYAEFLASLLALTRAREHGLDIERVAIATALLLRSIEWTTF-LDSTYPTALEQANVILRYFLAAGKIQIARQLFSVWQWMSDYKAIIRQIYVPDLILRLHAILFNSRNLKHALQ--L Rhior3 ----------------------------------------------------------------------------------------------------------------MCQT-WEDVIWANLNGENEMNR---ELASS-KFHQIQSTILQNNTSNLIEEMALRFISTLILF--GRTAIVAYYTEMSSRLENLTIAAYASRLTEQTNIYSQFLEGFILILLGKQYNLEMKKILKQTS-FQLAMDWLML-DKAFWLDALNAANYIIRFFMGIRHLYFAKRLLNIFEWRKEIE------------------LFNTINCYISLQ--L Rhoto1 ERNTWALVQALSVIRDWLHSIPLDPDALLRDAAYERALLRSLYVRAGELDLAIDMCRQQSWRAASLSGGNANRKLWKSMCRKLAAQNT-VDPYERALYGALSGDVTSVLP--VCSS-WEDVVWAHLNAESHVEAVFEKLLRS-DFHVSQAYLVIGKIDELLNAFLLRFFSHLILV--LRNRILEAYVHVLEAHDQNLIAFYASNLQSAVESYARFLLTFLALRKSREHGLSLPLIARRTVELIRSLEWLTA-EKETYEDAIKEANALARWFLSTDASSAARALYDCLDYREGIAALIRRLVVPDLVFRLHRVLYETSNLPLCLS--L Rozal11 DGDIWALVKKLMCILDWLHDKA-NPD----DRKYVCDIFRITLLRKGEHKRAMEIAESMYWLSSMINGGNKNRFLFKESCLKASQSQAGIDAFAKAIFGFLSGQVDLILP--VCKS-WEDHIWAYIHCEHEIDKTIEDIIRV-NISL----IISNNLESLVKVD--RFLCHLALY--LSDDLLLRYINYLTSKDMRQVAFYTKFLGLQVQAYSNFILNFALLAEAKSIGLNYQGIAKLAVQLVLSLEYLLA-EDRMISDSLIRFNKIMRLFLAFGKLSSCKLFLEGYS---EIADEIREKYVPDLVLKFQDLLYQTGFLKKSLE--I Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro SRATWLLLNDVRAVVSWLEQVALDPDAVSRDASEEAVFLKRILIRCGRLDMAIKLCQSQPWRAATLMAGN----LLERACLSLIENRS-TDKHERGVYASLMGKATPLLE--LSAS-WQDALWALLRTLERERSIVETLEDH-SHASVQKAIILGRPWSCLTAIYLCHFAHLALV--LRDDIIEAYVFDLIDKHMSCVAVYTSQIERQIAIYSFYLAGIHCLEEARKAGLPMAEITRAVVAVINALEWLLQ-DPQQKLHALQETNAVLRGFLLKDKLAAARAYVDADDWEHRRHKYLRRKCLPQSCLRIMDIFYDVE---------- Schco3 ERNTWALLQLLVVIREWVQDFALDPDATHHDMNYEKALAQALYIRAGRTREGADLCRDNPWRAACINGGNRNRRLWKRTCTRAALSTR-IADYDRIVFAALAPSPQTLKM--ACRT-WEDHLWTQVAIEEKISTALKSLETV-KFYFSQLKVIQGRTKELVELFVCRFFTHLCLF--LSQAIYESYLQLLEDAGEDLIALYASVLDNAVERYAMFLVSLAALHRAQEHGLDIARVAIATALLARSIEWTTF-MDATFPSALEHANLILRRFLASGRITLAMRFLKLWDWLTDYKALIRQIYIPDLVTRIHTLMLSSRNLKRALS--L Schpo1 ESRTWDLIQRLNIVFNWARDNSLDPDADIRDDNFERQFFHTALFRSGSFEELLELCRRNHWRSASLQGGNKRKELLRRSCLALTKNKR-IDSYERALYGALCGDLNSVLD--VCTT-WEDAMWAYYNSQYNLDVIFNSLSNS-SLIKLQTHIICNKISEILSSALLRILTHIILF--LKDSIIQAYIELLASAKKNLVPLYIQYLQVQYEAYSRFLILVEQLQLAKKYSLDINHAALLAVKLICTLEWL-L-ITSQTDELLRFANLVYRFFLSIGELNSARALCRALKWKKKLNFAIRNLYVPELILGLHNVYFSLEDYDSCFA--L Sorma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 EANTWQLIKLLTAVLSWLEETTADPDAPIRDADYESTLHRTAYIRRGQIEDAMDLYQQQPWRAASLQGGNQNRDLWKAVCFQIASNES-FDPYERATYAILAGDVQNAAQ--VCKH-WEDHLWMHYRADGMVDEIFEHLEKS-DFHVVQKSIILNTLNKFLSHFFLRFVTHFIIL--LRDFIIEKYVEMLTEAHKDLIAQYASYLGTQVDRYALFLQNVLAASNGLD--------CQRVARQIMALGWLLW-EPAMKEHALFCSNLLIRRFLALGRINSASSFFDAIQWMHDMKAILGDIYIPLIVNYYYQVLSETRNLQETMK--L Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 ERNTWWLLQELNIIREWLQDSAMDPDAPVRDASHEKALSQAICIRAGATMQAIELCEKQPWRAASIRGGNRRRKLWKATCIRAAHDPH-LTEAERIVYAALCPTLETLTS--ACRT-WEDVVWAQVSVEEKQNESLAVLSTA-PFHRVQLRIMLDQTGSMLDHFMTRFFAHLCLF--LQQIILEAYLQVLEAAGQDLIALYASALDNATSRYAAFLTSLQALSRAYEHGLDPVHVAVITATLARALEWSTA-QADTFGVALGHACIVLRYFLGAGRTKLASQFFLIWDWLNSYKNMIRAIYVPEMIVRLHHLLLDSRNVKHALE--L Tapde11 ECRTWDLVQRLKIVLDWLQDGKLDPDAPVRDEQYEKDLVRIMKVRSGNYKGAADLAQQEHWRAASLRGGSTNKPLWRRMCFALSQQPS-FDVYERAMYGALCGDVASVLP--VLST-WEDRLWVHYNAISRVEAILDGLFQN-ELRVVQARLITNQVGNLLEDMLIRFVAHLVIV--LRIAILQAYVEILISANQDAVAVYASQLHEAVEAFARFLVLVEQLRLALAHGIDTKVALLRTVKCIRALEWLPL-DNSLQTETIILGNTLFRKLLLSGRLSAACTLSKALTWKTEVARMLRNMYIPEVILSLHGVYSAQEDVASAMD--L Thetr EAHTWRLIAPLRIVVAWLQSLFLDPDAPLRDADLEERLLRHLLVKAGKLDEARNVCRKQPWRAASLGGGNVQRLLWRQMVQVLASEAS--SQYERALYGVLAGSLSAVLP--LCTS-WEDHLWARCATTSVLDTMFAALLSE-AFHTIQQLLITAQENAALVTLLLRFGASLVLF--FRVALLTGYVEHLIASGQALIALYTAQLSRQVGIYAKFLEGVDALRAAEAARLDVRAITSQVVRKVHSLQWLCF-YPDQRAEALVQANALARSLLLA-HVESAVAYLEVLSWQQAMGDSLRSVCIPSLCFMLHRVLYDTHDFAGSLK--V Treme1 EHRTWQLLRTVAVLIEHLQTRPLDPDFILRDQTYQTPLLATLLVRHGELDQAVKVCEQEPWRGATLMGGNRTRALWKKSCRAIAKNPT-LSAAERCLYAALISDLSTLIP--ACET-WEDHLWAHVQHENRLEAVFASISSV-QYYLAQKMIILDQTDQLLNRIYIRFFAHLVLL--LRNIILEAYLQILERDGNQLVAMYAACLGSGEESYARFLRSMRALSRAKQHDLDVAIIARETVYLIRSIEWLTM-VPETFTDALVKSNDLARYFLALGQANAARQLFVVFAWRKSLGSAIRQIFIPSLILQLHTLLYTHRMLQQALA--L Trire2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 ESKTWDLISSLLRVLRWLQDTAIDDDGPQRGSDSNRQITKSLFVRRGQIKEAIKMCELEPWQSAGLYGEATARNLWRTSCSQIAKDSN-ADLYERATYAALCGDVENTLP--ACST-WEDTVWAYYNAENLLHDIFSSAQRK-DFHYCQAMIITNRLDELVDALLLRFVTLLILY--LSDAIICEYIKCHSQSDNQIVALYCSKLEKQAHTYSTYLQHFLLIEVGQHHQLDVHRILWNLYRQIRSIEWLTF-DERLHPEAIIQSNAMIRCFLADGNISAADVLIETCGWASQFEQLLRQMYIPELVLNLHQVLFETQNLEKSLG--I Ustma22 EQSTWRLIHMLRIIREWLQETLLDPDAVSRDATYEKALLRTLYARAGRLDAAFDLCHQQSWRAATLRGGNRNRTLWKSACRKLSANPN-LDEYERALYGSLAGELQSVIH--VSQS-WEELLWAHVNAEAAVDLVFDKLSQT-QYRLVQRSIISNNLPDLFNRFLLRFFAHLILY--LRNAILSCYVQVLEAVGENLVAMYASSLQSATRSYANFLRSMNALRQAEQHDLDLTAVARCTVALVKAIDWLTF-DPTTYAEAITQSNALTRLFLSTGRLHAADTFFTALEWVKALSQVIRQAYIPEIVFRLHDMLVESSNLNMALR--L Walse1 ERNTWNLIHALNAIRQWLHNIPLDPDAPVRDSQYDKPLTRTLYVRLGRMDLALDACRSQPWRAASLRGGNKQRKLWKQIASQLSENPD-FDPYERALYGCLSGSLSSVLP--VCNS-WEDHLWARVNAERKIDDIFEEILKL--FRITQTNVMLERTSHLLTNFLLRFFAHLVLF--LREVILEAYVRTLEQRNEELVGMYAGCLGAGGESFAHYLYSLAALLQTLEHGLDLERVACRTVSLVRSIEWLIF-AKETYRYALIQSNGLMRYFLTSGNVSAAQQLFELLDWSDQVEALIREIYIPELVHRLHSSLYSAKYIDEALN--L Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3643.fasta_al_trimmed; alignment length = 205] Allma1 ATI-AVTFQKAMTVGELKDQLPLAEFGLPKLLLMGSTSEAIAQV----KAPVPYK---GQSSPAIDVLP--LPARALLDKLRNDVGIRGIMKQYKWRVGKLIELSPTEHTILGYNRNKGQVIALRLRTDDFEG-FRHYDSVRKVLLHELAHMVWSEHDDNFHALNRQLNKDVVELDLR-GNRL-LRLGGSTSSTPAERAARAALS Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MTL-TVHHHGDATLQDLSSTIPLST-LLPKLTLLGTPAQEIESLNAQTAAKH---RRPAPSIARLLPLS-YLPSLEFLARLRDDPGIRAAMAKHRFSVPLLTEMDPAEHTTLGLNRNKGEVIELRLRTDAYDG-YRDYRTIRKTLCHELAHCVFSEHDRDFWDLTAQIEKEVERADKHGGRRL-TVLGGLRDESRREIIARAAEE Aurde31 LNL-TITHRGDSTLDELQARITLTEAGLSKIMLLGSTAGEMDGMKAAEEKARREDRAAKGPTKRIAPLP-HLPAEALLKRLADDPAIRHVMQTHKFSVGLLTELAPHEAPLLGLNENRGQTIKLRLRTDRYDG-MRLYADVRRVLCHELTHNVWGDHDDNFKALNSKLNKEVAEFEAAGAHHLGGVLGGSAPSGRRAKALEAAMR Batde5 LNL-SVSYRATSTIDSIKCQI-LIDHIVPKLMLLGSSALEIDAVHK----------------HKLQPPP-TYCAMQLLDRLRRDWGVCTVMHKRGWTVGVLMELHPNERAILGYNRNKGQSIALRLRTNDLDG-FRHYSTIQDTFIHELAHMTHTDHDSNFHALNRQLKKEIDAINNKVG-----VLGGGQLAVSRKVLETAATL Botbo1 ---------------------------------------------------------------QIKPLE-HLPAKAFLTRLANDSGIMHVMQKHGYSIGVLTELAPHEYPLLGLNTNKGQIISLRIRTNAYDG-FRLYSDVRKVLVHELTHCVWGDHDDNFKKLNSQHNREVLEFEKAGTHSL-SRLGGAEITERRARILDATTK Botci1 VSI-TITHHGTATITDLSDSISLP---IPKITLMGSTIAEASSVAAGAAASRSVNTRPAPKVSTLRPLP-YLPSLQFLQRLKDDAGIKAAMRKHKFTVPLLTEMNPIEHTTLGLNRNQGEVIELRLRTDA--------------------------------------------------------TGVNSGASRREILAKAAEE Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow IHF-DVTFSR--TLLRLQLELALATGGTLRIMLLGSTLTDVEEVRQAEEERRLMR---QSSQSRLESLP-YFTALELLRRLSTDPGIVAVVKKHHWLVGALVEMPPEGKVVLGYNTNKGQSIALRLRTDDLTG-FRQYNVIKKTLIHELAHMVHSDHNADFHALNKQLTQETEQLDRNGGHAL-GALGGGSF-PRTELAALAALS Catan2 ISL-AISFQRSTTVLHVKESV-LANVGLVKLMLTGSSSADVQKI----RVRQPFK---TPVAAEISVLA--LPARSILERLRDDQGIRGIMQQNKWAVGRLIELSPTEHTILGYNQNKGATIALRLRTSDFSG-FRHFDSIRKVLLHELAHMVWSEHDENFHALNRKLNKDLVAFDRR-GNRL-NVLGGGT-------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 IQI-TLTHHGDATIFDLSERVALP---LTKITLMGSTKEEVSSLNSTIAAS----RRPGPIKATLRPLP-YLPSLRFLERLRDDAGIKAAMRTHKFSVPLLTEMDPAMHTTLGLNRNKGEVIELRLRTDAYDG-YRDYKTIRNTLCHELAHNVWGPHDRNFWNLCKQIEREVARDDKSGGRSV-GTLGAVSGGSRREILARAAEE Coere1 -SV-KVSHKGTTTLNQLRTEI---ESLVPKIILVGATTQEYSTLQKNVQKGR---KYKATSASVLEPLV-QLPAMEILRRLANDIGVWEVMRKHEYRVGVLRELHPNERSILGYNRNRGQVIALRLRTDDLEG-FRDYLGVRQVLMHELAHMVWDKHDDNFHRLNRQHCREVIELDQR-GRTV-GVLGGQI----RDQAYQAWLR Conco1 ----------------------------P--IVL-----------------------------KLQVLP-NHPAMEYLEKLRDDIGIKALLNHYKWSIPNLIELSPLEHTILGYNRNKGETIALRLRTSDFQG-FIHYPEVKRVMIHELAHMVHSEHNADFHQFNRLLMQQVKEFDKSQGYTL-Q-LGGGD--MREKILK-ATEK Conpu1 ISI-KVSYRGDASLSALQDLLTLSSAGIRTITLLGPTPGELSALEATEAHQKRERRAKKPQTKSIAPLP-HLPARDQLTRLANDPAVKHIMRMHQFSVGLLTELAPHEHPLLGLNTNRGESIKLRIRTDKYDG-FRPYLEVRRVLCHELAHNVWGDHDNNFKELNSRLNREVAEYEATGTHVL-SVSGTALS-DRRRRMLDAATA Copci MNI-TVSSRGDSLLSSLQAELTLADAGIKKIQMLGTTTKDLDGLKDVEEQKKRERRALKPQVKDIKPLE-HLPARAVLDKLATDPAIRHVMQKHRFTVGVLTELAPHEHPLLGLNVNKGEAIKLRIRTDRYDG-FRLYKEIRRVLCHELAHNVWGDHDNNFKELNSQLNREVFEYEMEGARTL-SVQRMASDGQRRRRVLEATLN Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 LSI-HISKGGDALLSDLITACT-----IAKVTLQVPTLEDLQGLRESSAARAR--RREAQRRARIEPLP-GLRSRELLVRLAEDPGIKAAMRKHKFTVGLLTEMDPLSNTLLGLNRNHGEAIELRLRTDAYDG-YRAYRTIRDTLCHELAHNVHGPHDRNFWDLCHQIEREVAAADRHGGQSV-GVLGASSSSSRRDVIARAAEE Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 VNI-AISYRGDSTLAALHDQLTLEQAGFKKVQLIGPKAEEVGEMHSVEEKRRKEERRMMNLPKHLVPLP-HLPALSLLQRLSSDPAIQHVMQAHKFSVGTLTEFAPHEHPLLGLNVNRGEAIKLRLRTDVYDG-FRLYADIRRVLCHELAHNVWGEHDNNFKTLNSRLNKDVADFEREGAHTL-S---GLSPAERRRRALDAAIN Fusgr1 LTL-SITHRKDATITDLFAEIDMP---LTALTLMGSPASEIQQVHDMAAARMAQRRSATPRRKQVRPLQ-GLPSQKLLMRLKEDPGIRATMTKHKFTVGILTEMEPLSNTILGLNRNQGEAIELRLRTDAHDG-YRDYKTIRKTLCHELAHNVHGPHDRNFWDLCHQIEREVDASDKSGGHTI-GVLGGTKTSSRREVLAQAALE Galma1 ISI-NVAFRGDSALAELHARLTLGQAGIKKIQMLGSTDKELDGMKAVEENQRRERRALKAPVKDMKALE-HLPALALLRRLSEDSAIKHVMQQHKFTVGLLTELAPHEHPLLGLNENAGQAIKLRLRTDKYDG-FRLYSEVRRVLCHELTHNVWGDHDENFKALNSRLNREVAEFEKDGTHHL-S--GGAPSSERRQRVLEATMN Ganpr1 ISV-TISYAGSLRLASLAERITLADVGVRKMMLIGTPAPAIASLHAHEARTLAAR---ALSLRTLEVLP-QFPAREVVERLSNDGAVKAVMERHGWRVGRLIELSPAERTILGYNQNRGHVIALRLRTSDLSG-FRHYPTIRRVLLHELSHMVHDEHDVQFHTLNSKLNKEVAEWEEGKGRTL-EVLGGTA--TREELRNRAAQS Gloin1 ISF-QVNFKG--TIHELKEYL-FRECNFKKVTLMGSSQEEIQVVKKAD-------LSNKSRSKRIEVIE-NFPARNILERLRDDKGIRAIMKKHKWNVGTLQELSPSERTILGFNRNYGQLISLRLRTNDMEG-FRHYPEIRKVLLHELTHNVWGEHDDNFHRLNRQLNKEVVNLDASGGNKI-SILGG----SKRELLAEAALI Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ISF-TVTHRGDCSLVDFQAQLTLAQAGFKKIQMLGTTTQELDGMKLVEERRRRERRALKTPVKEIKPLE-HLPAREFLTRLSDDLAIQHVMRKHEFSVGELTELAPHENPLLGLNVNKGQQIKLRIRTDRYDG-FRLYQDVRRVLCHELAHNIWGDHDNNFKELNSKLNREVAEFEVEGTHTL-S--KDSEPSERRRKVLEATMN Lenti61 III-SVSHRGHATLEYLQQRLAITEAGLKKVQLIGPTAEELGGLKATEEHQRKERRAQRAPVKSIEPLP-HLPARDLLTKLANDPAIRHVMNKHQFSVGVLTELAPHEQPLLGLNVNAGQAIKLRLRTDRYDG-FRTYKEVRRVLCHELTHNVWGDHDNNFKELNSTLNKEVAEFEAAGTHYLGSVLGGASTSERRRKVLEATMN Malgl1 YDI--LIHE-TMTVAELQEQILLPDVGLSRLTLVGAPVHEVEREQMQESLDKSY-RRLHPSLLRCRPHS-STQVRQYLERLASDPAVLHVCKLHHYKVGELCELLPHENPLLGLNVNKGQRILLRVRTDAADG-LRDYKTTRRVLLHELCHNEV--------------------------------------------------- Mellp23 VSL-TISHNK--TLYQLCHSITLQSLGF-KILLVTSSLEDVQKTEDHEAAKLAASR-TTPERNRIETLP-NPERRELLERLASDPSVKKVMVEHQFTVVHLGELHPVIHPILGVNENSGQSIKLRLLTDRLDG-LRSYAMVRRVLCHELAHNRFGPHLNDFKELDSSINRMMLAHDLASSHRL-GQLNDLEAE-PKQAAAAAALK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr IRI-DVKHEKEATWGDFQIELPLREMGYEKLLLIATSRSTVQELQEMESEQREQTSAQRDAAQSFAVLE-EFRALELLHRIAQDSGIVHILETHRWTIGLLKEFKPGLDTLLGYNQNKGQVIALRLRTDDFEG-FRHYHVIIETVLHELAHMEYQAHLAALQSGHTVAGRPGAAHDRLGGRTA-DTAGSAAARSRRDGDVRPASE Morel2 ------MFKG--TV------------TLVKIFVLGTTEKDIAKVHSIDNTRKSYR---APVAKPIQVLP-EFQARAVLERLKNDRGIIGIMKLHKWQVGALIELSPAQKTILGYNRNKGELIALRLRTDDLEG-FRHYDAVRKVLLHELAHNVWSEHDDNFHALNRQLNKEVQQLDAQNGSRV-AVLGGRA--TTRELVARAAQL Mucci2 INF-KVTFKS--TVGQIKQHL-LSQVGIQKLMLMGSLPTQVQQVNQLDQEQRKIAQKKKQAQRKISVIP-EFPARQLLERLRDDRGIRAIMAARKWSVGELIELTPFEATILGYNRNAGQLIALRLRTDDLSG-FRHYDSVRKVLLHELTHNVWGDHDDNFHALNRQLNKDVVNLDAHGAKSL-GRLGAGAKSQRRQRLATAALS Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MTI-KFAPEKDTTFEDILMALALP---MQSLRFMAPKKSALESLHAASAALQAQRRPAAPTSSTIRPLP-HLPSLSFLNRLASDPGIRAAMRSHQFTVGLLTEMDPGQYTILGLNRNKGEVIELRLRTDAYDG-YRDYKTIRKTLCHELAHNVHGDHDRQFWDLCKQIEREVERADTKNGRVV-GVLGA-SDATRREILAKAAEE Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -EL-TVHHHGSATLQDLSNELLLDA-ILQKITLLGTPAKAIADLHEQSAARR---QTPSSSRSRLLPLS-YLPSLDFLKRLRDDPGIRAAMAKHKFSVPLLTEMNPAEHTTLGLNRNKGEVIELRLRTDAYDG-YRDYRTIRKTLCHELAHCVFGPHDRDFWDLTSQIEKEVERADKSGGNQL-SVLGGLQGDSRREIMARAAEE Phybl2 LSF-RIGYKS--TVLGLKQHL-LADLQLSKITLMGSQPRQLKEAAEIDNERLTLA---KKTIKRITTLP-EFPAHKLLERLRDDRGVRAIMKARQWSVGELIELTPFEATLLGYNRNSGQLIAIRLRTDDLSG-FRHYDSIRKVLLHELTHNVWSAHDDNFHELNRQLNKDVVALDAHGGRSL-DRLGG----SQRELIARAASG Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ISI-KVTHRGDSTLADLQARLTLTDAGLKKVQLLGSTMNELGDMRAAEGQQKRERRALKPSAKRVEPLA-DPPLFAVLERLAADPAVAHVMRTHRFSVALLTELSPFQRQLHGVNTGSGAQIEVRLRTLVGGGLYKPYSEVRETLLHELAHNVHGHHEQPFVDLNMQLRREVAQYEKAGTHSL----GGPDLSERRRRALDATMK Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ITL-NIHHQNGISIHELCHQHSLHQLGFNRILLLTTELSEVQRSEQAAQARQAALRNTTPKHRQVALLP-NLPRQELVDKLATDPSILKQMIKFKLEVGSLGELHPWLDPLLGVNQNAGQSIRLRLLTDDLKS-VRPFTMVRRVLSHELAHNVFGPHDNQFKELDSKIHKGMLAYDKSSSYRL-GQLNQTVGSNPRLAAAEAALK Punst1 LKF-TVSHRGETTLTSLQARLTLSAAGIKRIQMLGSTADEIGGLHAVEEQRRKDKRALKAPAKRLEPLQ-HLPALSLLTRLSTDPAIQHIMQKHHFSVGLLTELAPHEQPLLGLNVNAGQAIKLRLRTDRYDG-FRTYNEVRRVLCHELTHNVWGDHDDNFKELNSKLNREVAEFERDGTHTL-SVLGGASSSDRRQRILNATMA Rhior3 ------------------------------MLLMGSSQKAIEKVNSMDDEQRRIA------AKKISVIE-EFPARNLLERLRDDRGIQAIMKTRKWSVGELIELTPFEASILGYNRNAGQLIALRLRTDDLSG-FRHYDSVRKVLLHELTHNVWGDHDDNFHALNRQLNKDVVALDAHGGHSL-GRLGG---SARRELLARATLS Rhoto1 LILLSVTHAGSSSTASLSETLTVAESRTKKALLVGTKRSELEAMEAQDLRRKKHTHQARPSSRHLEPFPKSVPRKAMLERLAEDPAVKDVMRRHKFAVGVLTELHPTLHTLLGLNTNAGQKISLRLLTDDLDG-LRSYNDVRRVLLHELSHNRFGDHDNNFKELNSLLNREVAAFE-----------------ERREKAGKAAEE Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro RVV-VVSYGK--TVGDLKARLELSDLKLRTMMLVGTQQSQVEQLKKTEEARERAL---KRGAVALEPLP-DSGALDLLKRLAADPNIYAIMKKHNWRVGILKEFAPSLETLLGYNQNKGQVIALRLRTDDFEG-FRHYHVIIQTLLHELAHMVHSKHDRKFWDLFRQLRKEYDELHKSGGRQL-QRLGGGTAPTAAEAARAAALR Schco3 LTL-HISHRGSTTWHELQTELSLADVGLKKLQMLGSTAEELGGMHAVEEKARRERRELKRPVSQIAPLP-HLPARALLQRLADDPAIRHVMQRHRFAVGLLTELAPHEHPLLGLNVNRGQEIKLRIRTDRYDG-FRLYSDIRRVLCHELSHNVHGDHDNDFKELNSLLNREVAQFEADGAHRLGG--GKTGTSQRRERMLQATMS Schpo1 MEL-KFSCRGNDTVLDAKEKLS----HLQESKIMCLIRQDKDIVNQAIVPDYSTNKPKKPHTTELVVLD-Y-PALRYLERLRDDTGIKKIMDSHRWTVPLLSEMDPAEHTTLGLNHNQGAHIELRLRTDRYDG-FRDYKTVKSTLIHELTHNVHGEHDSSFWELFRQLTKEADAADGKPGSYV-S--------HRRDLLLAAAER Sorma ITI-KFAPEKDTTFEDILMALSLA---MQSLRFMAPKKSALESLHAGKAALQAQRRPSASKS-TIRPLP-HLPSQAFLQRLAADPGIRTAMRAHQFTVGLLTEMDPGQYTILGLNRNKGEVIELRLRTDAYDG-YRHYNTIRKTLCHELAHNVHGDHDRHFWELCHQIEREVERADTKSGRVM-GVLGATSDATRREILAKAAEE Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ISF-SVTHKG--TISDVKAHL-LASIGVKKLLLIGSSAAEIHAVQEATQEAQARA---SQRPVSIRPLP-GFSATLLLKRLRDDAGIQSIMRNHKWSVGALVELHPSERTILGYNENKGQRIALRLRTDDLDG-FRYYDSIRKVLLHELAHMVHSDHNADFHALNRQLNREC---DTRGGRTL-GRLGG----SQREILAEAALK Sporo1 VHL-SISHSGSTRISQLVATVTLETLLTTKLLLIAPRSQDLHALQHAEAFEHHRS--------KLEPFPQSVPRLNMLERLSKDEAVLDLMKRHQFVVGVLI---PWRQK----NRAAPNLATDSTRTQHECG--------RKNLAQTL--------------------------------------------QRTTMISKSSIR Stehi1 LSLREISHRGDATLAELRSSITLSDAGFKKLQMLGNTDEELGGLRKVEEQKRVERRQAKGTVKRIEPLP-HLPALSFLQRLASDPAIKHVMQTNRLEVGLLTELAPHEHPLLGLNVNAGQAIKLRIRTNAYDG-FKLYADVRKVLCHELTHNVWGNHDDDFKEMNSRLNREVLAYEKAGTHTL-G--GVASLADRRRKILSATMS Tapde11 MQV-QVSYRGASTVAALKDLI--PDSIVQRFMLLATSAESISAVSTSL-------TRGTPGTRRIVALP-HLPSQTFLERLARDAAIRHLMRRRHLRVALLTELDPRAHTVLGLNRNAGEQVLLRVRTDTLDG-WRDYRTVRATLVHELAHNTHTDHDRAFWDLFNAMSREVAEFE--SGRAM--KLGRNGDGEGREARARAAEE Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 VAI-TVSHRGDLTVTDLFREIDYS---VRTVTVMGSTNADVQAVQSMCAAREAQRKSKAPARRQVRPLS-GLPSLKLLMRLKEDPGIRAAMRKHKFTVALLTEMEPLAHTTLGLNRNQGEVIELRLRTDAHDG-YRDYKTIRKTLCHELTHNVHGPHDRQFWDLCHQIEREVDAADKSSGHTL-GVLGGSRKASRREILAQAALE Umbra1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 FDL-TFVHRKTTTVSELRQAITLAEVGLSKLTVLGPSSQELERLYQDEELQKRN-RQYHPSLLSVYAHP-STPVIDYLTRLSRDPGILHICELHRFRIGSLTELLPWEHPLLGLNENAGQRILLRIRTDDAQG-FRDYKTTRRVLVHELAHNRISDHPPEFKILNSKLNAQIEAFEQDSTHSL----GGTSNPERRQRILEATMR Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3645.fasta_al_trimmed; alignment length = 131] Allma1 ESVLAILLAYLLNHEIRAGNTYPQEAYFLSADAFLAIHIAGMFYVKQNYPGRSSHICNGGFITGLGVGRAMALSFLRVAPLLGYRASVFNLVYTSNEASVRLWSAFGFKEIGRVPQAGRLRTDAIVFYFDF Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------- Aspfu1 VTMYPILVATLFRAEIEAGCTYPMEEYWFGTFAVVALECLGTFYIKPNYPGRCSHVCNAGFLTGRGVGIVMGETYLEYAPKLGYKYSVFNLVFENNIASVKIWKRLGFEVIGRVPGAARLEVDALIFGRKL Aurde31 LAIHHVLLQLLFNDELERGRTYPQEAYYFAADVFIGVSVAGCYYVKPNYPGRSSHVCNAGFFVGKGCGSLLGQSYLVNAPLLGYKASVFNLVYTNNVASVRIWEGLGFEKVGKIPRVGRLKVDAWVIWKEF Batde5 ----------------------------------------------------------------------------------------------------------------------------------- Botbo1 VYVHHLLVALLFVTELEIGFTYPQLAYFFARDVFVGICILGAYYVKPNYPGRSSHICNAGFITSLGIGTLLGTSYVHNAPRLGYQASVFNLVYASNVASLRIWERLGFEKVGKVPGAGK--IDAWVIWKEF Botci1 ----------------------------------------------------------------------------------------------------------------------------------- Caeel ----------------------------------------------------------------------------------------------------------------------------------- Canalb1 VTLFNILVKALFNYVVKEGRTYPYHKYWFTHFVSVLLIFLGTFYVKPNYTGRCSHVCNAGFIVGLGLGKELGKKYLQVAPELGYVYSVFNLVFETNIASLKIWDSLGFDRIGYVKNVAVLEVGAYMYGKDL Cangl ----------------------------------------------------------------------------------------------------------------------------------- Capow ----------------------------------------------------------------------------------------------------------------------------------- Catan2 IAIVPVLFAHLLNHEITQGNTYPQEAYFLSADAFVALHVAGTFYIKPNFPGRCSHVCNGGFIVARNVGVAMALAFVRLAPAIGYRASMFNLVFVSNQASVKLWTRCGFKVIGRIPRVGRLA-D-------- Cioin ----------------------------------------------------------------------------------------------------------------------------------- CocheC53 ATILPFLTSFLLALEIAAGDTYPMLPYWFSTFAAVMVRCLGSFYVKPNYPGRSSHVCNGGFLVNLGIGKALGRAYLEWAPRLGFTYSVFNLVYETNVASCKIWDSLGFERIGRVKKCAVLKVDAIVYGYDF Coere1 ----------------------------------------------------------------------------------------------------------------------------------- Conco1 ----------------------------------------------------------------------------------------------------------------------------------- Conpu1 ISIHHLLITYLFADEVDSGMTYPQEAYFFAADVLIAFCVAGYYYVKPNYPGRGSHICNAGFVVKKGYGHILARSYLHYGPRLGYTASVFNLVYVNNQASLKLWDALGFTRAGRIPNAGRLRVDAWVIYKSF Copci IAVHHLLLDYLFAAVVEEGRTYPQESYFFAADVFVGVSVSGFYYVKPNYPGRSSHICNAGFVVGRRYGKALAKSYLHYAPKLGYKASVFNLVYVNNVASVRIWDSLGFTRAGLIPGAGRLKVDALVFYKRF Croqu1 LTVLPLVLEYLFDAIVEEGRSYPQERYFLSHDFFVGICLAGMFYIKPNYPGRSSHCCNAGFVVGQKIGKSLAISYLYYAPRLGYRSSVFNLVYTNNLASMAIWDSLGFKRVGLIPEAGRLKVDAIVYWKKF CryneH991 LVTYPVLLRYFFSNELESGCTYPQESYFFAATTIIGICIGGCYYIKPNYPGRSSHNCNAGFIVGKKLGIALGKSYLEYAPRLGYRGSVFNLVYKNNIPSLSIWDQLGFQRVGVIPKAGRLKVDAVIIYKSL Crypa2 ----------------------------------------------------------------------------------------------------------------------------------- Debha1 VTLFPILLKVIINYVIEEGTTYPYHLYWFSAFVAVLIHFLGTFYVKPNYTGRCSHVCNAGFVVGLGLGKELGAKYLVWGPQLGYVYSVFNLVFETNTASLRIWNSLGFDRIGYVKNVAVLKVGAYMYGKDL Dekbr2 VTILPFLICRIMNDVIEEGTEYPQQDYYFPHFVAVMVKFSGCFYIKPNYVGRASHICNAGFLVGRKIGKTMGRNYIEMAPRLGYDYSVFNLVFKTNVASVKIWDDLGFQRIGLVPRAANLKVDAIMFGYSF Dicdi ----------------------------------------------------------------------------------------------------------------------------------- Dmel ----------------------------------------------------------------------------------------------------------------------------------- Enthi ----------------------------------------------------------------------------------------------------------------------------------- Falba ----------------------------------------------------------------------------------------------------------------------------------- Fomme1 IVMFHLLVAYMFADELERGDKYPQEAYFFAADVLVGICVAGFYYVKPNYPGRSSHICNAGFVVGQGFASVLARSYLHYAPRLGYQASVFNLVYVNNSANIHLKENLGFEKAGRIPHAGRLKVDAWVFYKSF Fusgr1 ----------------------------------------------------------------------------------------------------------------------------------- Galma1 ISIHHLFLEYLFSKEVEDGLTYPQEAYFFAADVFVGICIAGYYYIKPNYPGRSSHICNAGFVVGKGYGSLLAKSYIHYGPRLGYQASVFNLVYVNNLASVRLWENLGFTKTGRIPRAGRLRIDAWVIYKSF Ganpr1 VLVDRVSLEQMLNHEIRDGKTYPQEAYFLSYDAFAARELLGCFYIKPNFPGRCSHICNAGFLTNRGVGRALATAFLRLAPALGYRASMFNLVFESNEASVRLWRSFGFREIGRVPEAGRLKVDAIQFYYDF Gloin1 ----------------------------------------------------------------------------------------------------------------------------------- Hisca1 ----------------------------------------------------------------------------------------------------------------------------------- Klula1 VTAFPILVEFLFNEEVESGTSYPHFDYWFHSFAVVVLLVLGTFYVKPNYIGRCSHNCNAGFLVGKKIGYRLGQVYLKWAPLLGYNYSVFNLVFVTNPASWKIWDKLKFTRIGLVPKVAILNVDAIIFGKDL Lacbi2 ITVHHLLLDYLFASEIKNGQTYPQEAYFFAADVFVGICVAGYYYIKPNYPGRSSHICNAGFVVGNGYGFRLAKSFLHYAPLLGYRASIFNLVYVNNTASVRIWERLNFIKVGRIPEAGRVQVDALVFYKGF Lenti61 LTVHHILVDYLFADELERGQTYPQEAYYFAADVLVAVCIAGCYYVKPNYPGRSSHICNAGFLVGRGIGAVLARSYLYYGPTLGYEASVFNLVYVNNIASVKLWEALDFTKAGRIPRAGRLKVDAWVFYKKF Malgl1 ----------------------------------------------------------------------------------------------------------------------------------- Mellp23 ----------------------------------------------------------------------------------------------------------------------------------- Mnele ----------------------------------------------------------------------------------------------------------------------------------- Monbr LPLFVTDLEQALNEIITEGTTYPYLGYFLSHDAFVAK-VVGIFYIKPNFPGRCAHICNAGFCVRKGVARAMAQAYLQLAPQLGYHASMFNLV--------------------RAPRHSLPV---------- Morel2 ATLFAILVNAMFNTEVERGDTYPQENYFLGGDAFVLIDLLGFFYVKPNFPGRCSHICNGGFMVGLGLGGIMGKAFLKVVPLIGYKASMFNLVFESNVASVKLWRRLGFKEIGRVPNAGRLRVDAIQFYWDF Mucci2 GLIQKVLVDFLFNAEIEDGSTYPQEDYFLGSDAFVMSKVVGMFYIKPNYPGRCSHICNGGFFVGKGAGVVMGEAFKVLVPAIGYKASMFNLVFENNPASIAIWRKLGFQEVGRVPNAGRLKVDALMFYYDF Mydma ----------------------------------------------------------------------------------------------------------------------------------- Neucr2 ATVVPFLLHYLFNKEIEGGDTYPMLDYWFQNFAGVMLECLGTFYIKPNYPGRSSHICNAGFIVNRGVGRLMGETYLDWAPKLGYTYSVFNLVYETNVASCKIWDGLGFKRIGRVKGAGNLKVDAIIFGRDL Orpsp11 ----------------------------------------------------------------------------------------------------------------------------------- Pench1 MTLYPILIKFLFSAEILRGGTYPMMDYWFGTFAVVAIVCMGTFYTKPNYPGRCSHVCNGGFLTGKGVGQAMGEAYLDFAPRLGYTYSVFNLVFANNPASIRIWEKLGFSVIGRVPKAARLAVDALIFGREL Phybl2 ATLQRILVQYLFNGEIESGSTYPQEDYFLSYDAFVLTQVIGMYYVKPNYPGRASHICNGGFFTGLGAGVALGETYLIIAPALGYKASMFNLVFVNNEASIRIWRRLGFQEVGRVPKAARLNVDALMFYYDF Picst3 VTLLPVLVQVVFNYIVEEGQTYPHHKYWFSGFVAILIIFLGNFYIKPNYIGRCSHVCNAGFVVGLGLGKELGRKYLVWAPQLGYVYSVFNLVFETNIASLKIWDGLGFERIGYVKNVAVLKVGAHMFGKDL Plicr1 LVVHHLLIEHLFHAEVERGMTYPQEAYFFAADVFVGVSIAGFYYVKPNYPGRSSHICNGGFVVGRGYGTTLGRSYLHYAPKLGYKASVFNLVYVNNIASVKIWESLGFTKAGLIPKAGRLRVDAHIFYKSF Polpo ----------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LTVFPILWKHLFDSIVAEGRTYPQENYFLSHDVFIGVIIAGIYYIKPNYPGRSAHCCNGGFVVGRKVGKTLARSFLHYAPLLGYRASVFNLVYKNNLASIAIWDSLGFQRVGLIPKAGRLKIDAIVYWKEL Punst1 LTIHHLLLDYLFAEEIERGTTYPQEAYFFAADVLLAICVAGFYYVKPNYPGRSSHICNGGFVVGKKYASVLARSYLHYAPKLGYEATVFNLVFVNNYASVRVWEKLDFIKAGRIPRAGRLKVDAWVFYKSF Rhior3 GYIQKVLVSYLFNKEIEDGLTYPQESYFLGYDAFVMSKVMGMFYIKPNYPGRCSHICNGGFFVGIGVGIAMGEAFKILVPAIGYKASVFNLVFENNVASVAIWKKLGFEQVGRIPKAGRLRVDALIFYHDF Rhoto1 LTVFPVLLAYLFNDVVEEGRTYPQMAYFFAADCFIGICVLGMYYVKPNYPGRSSHLCNGGFVVGLRVGSTLGRSYLHYAPLLGYRGSVFNLVYVSNVASVKIWDGLGFQRAGLIPGAGKLKVDAIVYNYQF Rozal11 ----------------------------------------------------------------------------------------------------------------------------------- Sacce1 ----------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------MFNLVFTCNVPSVRLWQRLGFQQIGLLPNAGNMKSDAIIFYKAF Schco3 VTVHHLLPEYLFGDELERGLTYPQEAYFFAADVFVAVCLVGYYYVKPNYPGRSSHICNAGFVVGGGFGVVLADTYLHYAPKLGYQASVFNLVYVNNVASIRLWERLGFTKAGRIPRAGRLKVDAWVFYKSF Schpo1 ------LLSTLINYEIEMGQTYPIDDFFFKFCTVICVSLLGAFYIKPNYPGRCSHICNGGFLVSKGIGRNLANAYLYFAPRIGFKSSVFNLVFATNIKSIRLWERLNFTRAGIIKDAGRLKVDAYIYQYHF Sorma ----------------------------------------------------------------------------------------------------------------------------------- Sphar VELDFF-----MNQIIVEGQSWPFMCYFLSHAAFVVRAILGCFYVKPNFPDRCSGICNGGFITRRGVAKLMGKLYCRLAKDLGYRGCLFNLVFASNEASLRLWDGLGFTRLACLPQCAELKTDAYQYYRNL Spipu1 ATLSRVLTERILNAEIEAGNTYPQENYFLSGDAFAVRELLGTFYIKPNFPGRCSHICNGGFIVGLGVGREMAKAFLVLAPILGYQASMFNLVFETNTASVNLWQSLGFQQIGRVPKAGRLRVDALVFYYDF Sporo1 LTLFPVLVEYLFNDTVEDGRTYPQQS--LGSNRFRFVAVLGITVLQPNYPGRSSHNCNAGFVVGLRIGSTLGKSYLHFGPLLGYRGSVFNLVYISNAASVRIWDALGFTRAGLIPKAGLLRVDAIVFHYDF Stehi1 LTVHHLLLSYTFAQVLEDGRTYPQEAYFWAADVFVAICVAGWYYVKPNYPGRASHNCNGGFIVQKGYAKILAKSYLHYAPKLGYRASVFNLVYVNNMGSVRTWDALGFTRAGLIPRAGRLRVDAIVFYKSF Tapde11 ----------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------- Treme1 LWTFPVLLHHVLNTEIQDGKTYPQEAYYFSSVTIIGLSLGGTYYIKPNYPGRSSH--NAGFLVGRGVGAALAKSFCEYAPQLGYKSSVFNLVYANNTASLRLWDSLGFSRVGLIPQAGRLRVDAVVIYKSF Trire2 ----------------------------------------------------------------------------------------------------------------------------------- Umbra1 VTIEAVLVLYMFNVEIEDGSTYPQEAYFTAYDSFIAVSVMGMFYVKPNYPGRCSHICNGGFFTGQGIGKVMGRAFVTLVPLLGYKASVFNLVFANNPASLRIWRSLGFQEVGRIPQAGRLKVDAIIFYKDF Ustma22 VVMIPFLIEYLFNAELERGVTYPQRGYFLGYDLIVGFQVAGFYYIKPNYPGRSSHLCNAGFVVGLGLGGVFGRSFLHFGPQAGYKGSVFNLVYVNNTASVKIWQRLGFTIIGRLPMAGLLKTDAYIIFKDF Walse1 LYVHHLLLSRLFNFIIEEGRTYPIESYFFAADLFVGLVLGGCYYVKPNYVGRSGHICNAGFIVGLKLGSTLGKSYLHYGPKLGYKGSIFNLVYQSNIASSRIWDGLGFTRIGIVPKAGRLIDDAIIYYKSF Zygro1 AIAYPILIDYMFNYVIEEGLTYPQAHHWFHSFCVVAIVFLGTFYIKPNYMARCSHNCNAGFLVGQKIGYRLGQVYLKWGALLGYKYSVFNLVFVTNVASWKLWDKFKFDRIGLLPRAAILKIDAIIYGRDL [Cluster3653.fasta_al_trimmed; alignment length = 63] Allma1 --------------------------------------------------------------- Ashgo11 --------------------------------------------------------------- Aspfu1 FEALIPYGIIIAMFGVTGAGLTAAKNEGKKNKDLWDRMMERDLRITGTLRGQSVAPKGFDVSN Aurde31 WEALIPFALLTTMFGAAGTLFGGAQNQGKLGLDSWEEMMERDRRLTGHVRGQTVAPKDFSTNS Batde5 AEALSALVAIGLVTAATSFGIKAMQNDDKPGVDKWDRMMERDGRLTGNVNVQMKAPLQFSRNS Botbo1 WEALIPFALVTTMFGVTGTAFSITKNDGKPGIDTWDEMMDRDKRLTGSARGQSVAPESFATNS Botci1 FEALLPYGIMLAMFGITGAGMSGVRNGGKRSVDAWDR-------------------------- Caeel --------------------------------------------------------------- Canalb1 FEGLLPYAIMTAFFGLAGHGVQFIRNGWKNHLDEWDDMMARDLLLTGVKRGQTVAPESFKTAE Cangl --------------------------------------------------------------- Capow --------------------------------------------------------------- Catan2 FEALLPLGVIAGMFAAAGAGIGALQTLGKANLDQWDRMMARNERLTGHTYGQSVAPEEFSRST Cioin --------------------------------------------------------------- CocheC53 FEALLPYAIMTGFFAFSAVSVGKLQNGGKRGIDAWDRMMERDRRLTGFMRGQTVAPAGFELNN Coere1 FESFIPFGIMSAMFVVTGVGINFAQNEGKKSMDDWDRMMTRDKQLTGTPRGQNVAPPEFKINS Conco1 --------------------------------------------------------------- Conpu1 WEALIPFGLLTTMFAAAGTLLNTSKNQGKRNLDAWDDMMDRDRRLTGHIRGQKTPPPGFETSS Copci ------------MFGTAGTLFNISTNEGLPNLDKWETMMERDKRLTGTKRGQTIAPEHFATSS Croqu1 WEAFIPFGLLTVMFTGAGTLLNTTRNDGKPGTDKWDEMMERDRRLTGSTRGQSIAPPQFQTNS CryneH991 WEALIPCGLLVAMFGVTGNLFSVAKNDMKPALDTWENMMERDRRLTGSLRGQSIAPKEFATNS Crypa2 FETFLPYAIVFTMFGVTGAGLSNIKNGKKRSLDQWDRMMDRDRRLTGEIRGQSIAPPGYELNN Debha1 FEGLIPYAIMAAFFGVAGHGVGFVRNGWKNNLDSWDEMMERDFLLTGVKRGQTVAPDHFKTAD Dekbr2 --------------------------------------------------------------- Dicdi --------------------------------------------------------------- Dmel --------------------------------------------------------------- Enthi --------------------------------------------------------------- Falba --------------------------------------------------------------- Fomme1 WEALIPFGLLTTMFAAAGTLLNVSQNLGKPHIDDWDEMMERDKRLSGHRRGQRIAPENFSTNS Fusgr1 FEALLPYAIMIGMFGISGTGLAVIKNEGKRSVDQWDRMMDRDRRLTGTLRGQTEAPLGFELNN Galma1 WEALIPFGLLTAMFGVAGTLVNVSQNQGKPSIDNWDKMMNRDKQLTGHVRGQSIAPPEFSKNS Ganpr1 ------MLYIA------SYGLMGAQNEWKPRMDDWDRMMERDARLTGTKRGQAEAPAAFATNS Gloin1 FEALIPLGLVTAMFGVTGSLLNLSRNEGKPSMDKWDKMSERDKRLTGSSSHQSIAPPGFNTSS Hisca1 FEALLPYGIIMVMFGVTGVGLSTVKNGRKNAIDMWDKMMERDRRITGIFRGQNEAPAGFEVNN Klula1 --------------------------------------------------------------- Lacbi2 WEALIPFGLLTAMFGTAGTLLNLSTNMGKPRIDNWDEMMKRDERLTGHKRGQTVAPPGFETSS Lenti61 WEALIPFGLVTVMFGATGTLLNTSKNQGKPNVDAWDDMMDRDKRLTGHKRGQVYAPDEFETNS Malgl1 FEAIIPMGIVVALFGVTGTGYNAVANEGKPNLDEWERMMRRDQRLTGTRRGQSIAPEQFATNS Mellp23 WEAFIPFGLLTVMFTGAGTLLNTTRNDGKPGTDKWDEMMERDRRLTGSTRGQSIAPPQFQTNS Mnele --------------------------------------------------------------- Monbr TESIPAFAVIIGGMASSGLIIGGIQHSGHTGLDSFSRMMQRDEAITGKQYAQNFVPSA----- Morel2 FEALIPLGLITGFFGVSGLLFQKLKNEGQPGLDRWDRMLDRDYRLTGTQRGQTAAPSAFSTSS Mucci2 FEALLPFAIIAGMFTVTATGLNVTRNDKKPGLDVWEKMMERDRRLTGSLRGQTIAPLAFATNR Mydma --------------------------------------------------------------- Neucr2 FEALIPYAIIVTMFGVTGAGLSAIKNGGKKSLDTWDRMMDRDRRLTGWLRGQTDAPYGFEYNN Orpsp11 --------------------------------------------------------------- Pench1 FEALLPYGIIITMFGVSGYGLHYVKNDGKKNRDLWDRMMERDQRITGSFRGQSQAPTGFEVSN Phybl2 FESFLPFVIIASFYCVTASGLSVARNDKKPGLDTWERMMERDRRLTGSKRGQSVAPAIFSTNS Picst3 FEGLLPYAIMTAFFGVAGHGVGFIRNGWKKDLDSWDEMMNRDFLLTGVKRGQSVAPESFKTAD Plicr1 WEALIPFGLLTVMFGAAGTLLGASKNQGKPNIDAWDEMMDRDRRLTGHPRGQTSAPASFSTNS Polpo --------------------------------------------------------------- Pucgr2 WETFIPLGLLTVMFGASGTLLNAARNDGKPTVDKWDEMQERNRRLTGSLRGQCKAPLEFQTSS Punst1 --------------------------------------------------------------- Rhior3 FESLLPFAIITGLFTVTATGLNITRNDRKPGLDLWEKMMERDRRLTGSLRGQTIAPAAFATNS Rhoto1 FEALIPFGLLTVMFAVTGTGFSAVRNDGKPTLDRWEEMMERDQRLTGSLRGQSIAPKGFSNNS Rozal11 --------------------------------------------------------------- Sacce1 --------------------------------------------------------------- Salro --------------------------------------------------------------- Schco3 WEALLPLGIMTAFFGVTGTALNLTENLGRSNLDQWDTMINRDYRLTGHKRGQSYAPEGYETRP Schpo1 --------------------------------------------------------------- Sorma FEALIPYAIIVTMFGVTGAGLSAIKNGGKKSLDTWDRVMDRDRRLTGWLRGQTDAPYGFEYNN Sphar --------------------------------------------------------------- Spipu1 IQPLFPLMIIGVLGVTMRWGVKKYQNWGKPSVDRWDRMMERDSRLTGNVNFQREAPKEFLTNS Sporo1 FEALVPFGLLTVMFAVTGTGFSAARNEGKPTLDTWEEMMERDRRLTGTLRGQSIAPKNFSTNS Stehi1 WEALIPFGLVTAMFGAAGTLLNVSKNQGKGKLDPWEEMMDRDERLTGHARKQKMAPEGFDTSS Tapde11 --------------------------------------------------------------- Thetr --------------------------------------------------------------- Treme1 FEALIPFGLLTVCFAATGTLFSIAKNDWKPNIDTWDEMMERDRRLTGSFRGQSIAPKEFATNS Trire2 FETLLPYGIMIVMFGATGTGLAAFKNEGKRSLDQWDKMMERDRRLTGTLRGQTQAPLGFEFSN Umbra1 IEAVIPFAVIATFFTLTGSGLSAVKNDKKPGLDYWESMMERDRRLTGSIRGQSVAPPEFSINS Ustma22 FEAVLHMGMVVVMFGVAGTGYNVVREDGKPSLDDWERMMKRDERLTGSLRGQSIAPKEFATNS Walse1 FEALVPVGLITVMFGVVSVGMNSMKNDWKPNVDQFEQMMKRDERLTGSNRGQRIAPPEFATNS Zygro1 --------------------------------------------------------------- [Cluster3654.fasta_al_trimmed; alignment length = 122] Allma1 -------------------------------------------------------------------------------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------- Aspfu1 LPS--ISSLRALDTLFEPSPELLMAPVLSYNSLIDAVGIMGSHPRLGRMSELSKREQASEAQ--AEKLLNVEYEERFPGLRFVTFVNGRSRDVIMEEMRRRIERQETIQAMCDIAKDRAKKL Aurde31 LPP--IAKL-ALSLLFEPSSVLTLVPALSYDQLIDHALFIAAHPRIGALSAMSAAEQATPQD-VLERLLNALYEQRFTGLRYITFVNGRSRAEVAQDMEK--ELERAVEEVGLIAKSRVGKL Batde5 LPS--IDLLSIISVLFEAAPP--LANALSYATILSTAAVVNAHPRIGALSALSYQEQGEDR--INQRLLNAQYEAKF-KFCFVVFVNGRSREEIIPVIEARLELSNGLEHMIQIAQDRLKKV Botbo1 IPP--LSSVHALSVLFEPSPALILTPRLSYSGLIDRTGFISGHPRIGELSKLSEREQATPPE-VLRRLLNACYERKYPGLRYITFVNGRTRAQIVPEIEGKLELERAIADIGLIAKSRLKNL Botci1 IPP--IAGISVLDALFEPCAALLSLDLLSYSDLIASVKILGSHPRLGE-SVQSKAEQAPTEE--AEKLLNEEYEKTFPGLRYVVFVNGRSRPVIFEDMRRRIERKEAIQAMCNIAVDRASKL Caeel -------------------------------------------------------------------------------------------------------------------------- Canalb1 LPT--IESFQVLDHLFEPCNTLFVFIKVTYPEFINLVEIISAHPRLGELSVHSNNEQKDPEI--IKKLLNAAYEKTFPGLRYVVFVNGRSRHEIMDNMQKRIERVEAFNAMCDIALDRANKL Cangl -------------------------------------------------------------------------------------------------------------------------- Capow LPS--IEQVEATSVLFESTRA--LTARLSYEALIDAADILNAHPRIGALSALSKREQGIDER-TLAELLNVAYEAKY-GFKFVIF---------------RLEVATGMRAMLDIARDRLSKL Catan2 -------------------------------------------------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------------------------------------------------- CocheC53 LPP--ISSLSTLDLLFEPSPALLSLPVLSYPVLIAAVEILCAHPRLGA-SEQSRAEQA-AGE--GEELLNEEYEAVFPGLRYVVFVNGRSRPEIMHNMRDRIERQEAIQAMCDIALDRAGKL Coere1 LPS--IGEIRVISLLFEPTAL--LASRISYDQLLDKAGIVNAHPRIGELSELSRIEQGDNEE-SLK-LLNKEYEDKY-GFRFVIFVNGRSKESLIPIIEKRIELATGLSEMVDIARDRVKKL Conco1 VPT--IDQLSFISNLFEPCPI--LITPLSYEDLLSKVEIINAHPRLGALSEHSFKEQGEQLA-IRKELLNDAYEKQF-GFKFMIFVNGRNFXXXXXXXXXXX-------------------- Conpu1 LPA--LSDKGVLSLLFEPSEILKLVPQLSYSDLIDEAAFIAGHPRIGELSVLSNKEQGTPPE-VLSRLLNACYEQRYPGLRYIIFVNGRSRAEVAEVMEDALELDRAIQDVGLIAKSRLRSL Copci LPP--LTDITALSILFEHSPILILQPQLSYAQLVDLSEFISGHPRIGELSKLSAKEQGTPPE-VLARLLNAGYEVKYPGLRYITFVNGRSRVTIAEEMEGVLELKRAVKDVGLIAKSRLRAL Croqu1 -------------------------------------------------------------------------------------------------------------------------- CryneH991 IPS--LATLIVLSTLFEPSPPLLLVPSVSYNQLIDICEFLSGHPMIGELSKLSGKEQSTSKE-VLERLLNQLYCKVYPGLRYITFVNGRTRAQIIPEFESILECDRGLQDVWLIGRARLKGL Crypa2 LPD--ATMLSVLDLLFEPSHDLLALPTLTYPDMIDTLSILGSHPRLGE-SAQSAAEQAAESE--AEVLLNREYEARYPGLRYVTFVNGRSRDIIMEDMRRRIEEAEAIHAMADIAKDRAGKL Debha1 LPP--ANQLEALNHLFEPCPTLLLISKVDYPEMIERCKIIAAHPRLGQLSAHSSQEQRSEEE--SRKLLNEQYEATFPGLRYVVFVNGRPRSVIMQNMIDRIERRDAFNAMCDIALDRAKKL Dekbr2 LPD--PQALTVIDTLFEHNDKFFIIKKVSYREFIKAVSVISAHPRLGILSVSSAREQKKPEL--ERQLLNQEYEHCFPGLRFVVFVNGRSRQEITKIMRKRIEVRDAFSAMCDIALDRIKKE Dicdi -------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------- Fomme1 -------------------------------------------------------------------------------------------------------------------------- Fusgr1 LPP---KELKTLDLLFEPSPAITLIPVLSYPELIDACSILGSHPRLGA-SAQSAAEQA--GQ--GEELLNQEYEEKFPGLRYVVFVNGRGRPEIMENMKARIEVAEALQAMCDIAKDRASKL Galma1 LPT--LEDVLTLETLFEHSPILVLEPQLSYTKLIDVAEFISGHPRIGELSKFSAREQETPPE-VLARLLNACYEKKYPGLRYITFVNGRSRAAIVEELEEVLELDRAVYDVGRIAKSRLGAL Ganpr1 LPE--VSSISALSLIFERSETLLLSNHVSWYALVDDFEIINAHPRLGELSAMSLKEQGPDEQ-VNAKLLNGQYEARF-GFKFVIFVAGRPRREIVPIFADAVEMARGLRDMCDIGRDRIKKL Gloin1 LIP--ISELNKINILFETALP--LANALSYTSLISSAEIINAHPRLGELSSLSLKEQGEDEI-VNTILLNYKYEEKF-GFRFVIFVNGRSRKEIIPILQDKLELKRGLLDMMNIANDRLRRC Hisca1 LPA--ISTVQILDTLFEASMDLLALPLLSYQSLISAVSILRAHPRLGELSELSRQEQAAEEE--TAELWNDLYEEKFPGLRYVVFVNGRGRDILMQDMQRRIEKEDIIQAMCDIAIDRARRL Klula1 LPS--IDEFDILDVLFEHSDSLTLQNSRSYVELVNAINIVGAHPRLGDLSVHSMKEQADSLE-ILTWLLNDKYEKKYEGLKFVVFVNGRSYDRISKLMEQRIECRIAINEMTDIAIDRLNKC Lacbi2 LPS--LAEIRALSLLFEPSPILTLEPQLSYDQLIDLAEFISGHPRIGELSTLSAKEQGTPPE-VLARLLNPCYETCYPGLRYITFVNGRSRAVIAEEMEDVLELNRAVQDVGRIAKSRLESL Lenti61 LPP-LLEAIRALALLFEPSPVLTLVPGVSYRALIDASQFTAGHPRIGELSKLSAQEQATPPE-VLARLLNALYERKYPGLVYITFVNGRSRAEIKDEMEDKLELERAVADVGRIAKSRLRSL Malgl1 -------------------------------------------------------------------------------------------------------------------------- Mellp23 LPP--IEKVKALSLLFEVSESICLIPLLTYEDLILVCSFLGSHPRIGELSKISANEQQDPKNCFDVALLNRVYEASYPGLRYVTFVNGRSREEIMHEMQHKLEVARGIKDVFKIAVSRLGVL Mnele -------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------- Morel2 LPT--IEFISAVTLLFEPAPP--IVAHLSFSALIDETDVINAHPRIGALSALSLIEQGDDEE-TQRTLLNEEYEAKY-GFKFVVFVNGRPRNVIIPVMEERIEMKVAMDDMVAIARDRLKKL Mucci2 IPS--IEQLQAVNTLFETAPP--LAKRLSYIQLIDYAEVMNAHPRIGALSANSLKEQGQDEA-VNAELLNQQYEDQY-GFKFVVFVNGRPRNQIIPIIKERMELYVGITDMMLIAKDRLKK- Mydma -------------------------------------------------------------------------------------------------------------------------- Neucr2 LPA--ITSLSTLDLLFEPSPDLLALPTLSYDDLISTLAILGSHPRLGELSAQSRKEQAGDSEEVKEELLNKMYEETFPGLRYVVWVNGRGRGEVMADMRRRIEEREGIQAMCDIAADRAAKL Orpsp11 -------------------------------------------------------------------------------------------------------------------------- Pench1 LPP--LSTIRVLDTLFEPSPELLMIPVLSYTNLIDAVGILGSHPRLGRLSELSKKEQAAEEQ--AEKLLNAEYEEKFPGLRFVTFVNGRSRDVIMVEMRQRIEIEETIQ-------DRARKL Phybl2 LP---IEKIEAVNTLFEVAPP--LAQKLSYSQLIDYADIINAHPRIGELSAMSLKEQGEDQQ-VNDTLLNKAYEDKY-GFKFVVFVAGRPRSQIIPVVQERIELETGLTDMMLIARDRLKK- Picst3 LPS--ISLFEVLAHLFERCETLLIFSTVSYTQLIEAVKIIAAHPRLGGLSQHSSLEQKSAEE--ALLLLNDEYESVFPGLRYVVFVNGRSRPVVMENMLSRIEREEAFEAMCDIANDRASKL Plicr1 LSP-INEALSALSTLLEPSPVLKLTPQLSYSHVIDIAEFIAGHPRIGELSSLSAKEQGTPPE-VLARLLNACYERRYPGLRYITFVNGRSRAEIAVEIEDVLELKRAVVDVGRIAKSRLATL Polpo LPA--VQRLNVVNLLFETAPP--LARGMNYEQLIQTAELLNSHPKIGAVSTLSYKEQGDEAK-VLERLLNVAYQEKY-GFTFMVFVNGRSKAEIIPILEKRLELQTGISEFFDIASSRLAKL Pucgr2 -------------------------------------------------------------------------------------------------------------------------- Punst1 LPL--IADLQTLAILFEPTPVLHLLPQLTYSELIDASQFIAGHPRIGELSKLSAAEQATSPA-VLARLLNACYEHVYPGLRYITFVNGRTRAEVLEEMEAALEMQRAVVDVGRIAKSRASSL Rhior3 ILS--IKALENVNILFETAPP--LANRLSYDALIEEAEIINAHPRIGELSAMSQKEQG------------KGGEDQ---------------------------------------------- Rhoto1 LPPPRIDILPVLEQLLEPSPPLLLTPQLSYSDLLALAAFLAAHPRIGELSKASEGEQATPAQ-VLKRLLNSLYEDAFPGLRFITFVNGRSRAEIVPELESLLELKRGLRDMWLIAKSRAEKM Rozal11 -------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------- Schco3 LPP--LAALSTLSLLLEPSPILRLVPELSYAALIDLAQFIAGHPRIGELSHLSAKEQATPPE-VLARLLNAYYERRYPGLIYITFVNGRSRAEIAREMEDKLEVTRAVGDVGKIAKSRLRAL Schpo1 -------------------------------------------------------------------------------------------------------------------------- Sorma LPS--ITSLSTLDLLFEPSPELLALPTLSYPDLISTLAILGSHPRLGELSAQSKKEQAGDSEEVKEQLLNKEYEERFPGLRYVVWVNGRPRSEIMADMRRRIEEREGIKAMCDIAADRAAKL Sphar --------M----------------------------KILAAHPMIGQLSAHSAKEQGTPAE-VIELLLNKEYQDKF-GFCFVVFVNGRPKKDIIPVLESRLECKEGLKAMVLIAEDRFKKM Spipu1 -------------------------------------------------------------------------------------------------------------------------- Sporo1 -------SLPVLELLLEPSPPLLLAPQLSYAQLLDLSEFIASHPRIGELSKASESEQGTSGH-VLRRLLNAFYEETFPGLRFITFVNGRSRAEIVPELEAILELDRDLVNMWQIAKNRLSKM Stehi1 LPS--LSQISALSTLFEPSPILKLVPELTYNSLIDFASFVGAHPRIGELSALSASEQATPPE-VLERLLNEAYERKFEGLRYITFVNGRSRKEVMQEMQEVLECRRAVEDVAKIAKSRLSAL Tapde11 -----TAKVHEVDLLFEPSEALLLSGHQVSEDLVTFVAVLNAHPRLGA-SAQSVHEQRSAAE--RDRLLNEAYEARFPGLRYVVFVNGRSRAVVMDDMARRIERREAIAAMVDIALDRLRHR Thetr -------------------------------------------------------------------------------------------------------------------------- Treme1 LPP--LSSLEALSKLFEPSHPLLLVPQLTYFELIDICEFLSGHPEIGAISN---TEQNTSQA-VLRRLLNSLYRIVFPGLVYITFVNGRPRSDIVPELERIIECERGLGEVWKIARARLKTM Trire2 LPP--IAALEVLDLLFEPSPAITLLPVISYPDLIDACSVLGSHPRLGD-SPQSVAEQASEAE--AEELLNKEYEEAFPGLRYVVYVNGRSRPEIMEDMRARIEVIAATQAMCDIAKDRASKL Umbra1 LPS--IQQLAVVNTLFETAPP--LADKLSYIQLIERGEVINAHPRIGELSAMSLKEQGEDQA-VNERLLNKKYEDQY-GFKFVVFVAGRPRKDIIPVIEERIELKTGIVDMMLIARDRLKKL Ustma22 -------------------------------------------------------------------------------------------------------------------------- Walse1 -----YNELEYLSNVLEPSEPLLLVPQLNYLDCLEVALFVNSHPRIGQLSKLSREEQATPED-VLIKLLNRAYEEKYPKQRFITFVNGRTRAEIIPEIESILELDRNINAIFLIAISRT--- Zygro1 -----YQNF-VMNELFEPCQG--LIRLTNYKEFIELVDVVNAHPRLGELSTHSMLEQKDSPE-IQKKLLNHEYEKVYPGLRFVVFVNGRTRLEIIRIMESRIEVRTAMQELCNIAQDRYRKN [Cluster3658.fasta_al_trimmed; alignment length = 158] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MLMDLLYEMSRIQRIRIEDLVLVDDDFIKGLFEIIEDLSSDPYHYVIRVLLVFNEQFMISNKVIKVLAMHKTFGENIILLINRELQLLTLKLLYLIFTTSTYEYFYTNDLHVLVDILIRNLLDLSALRHTYLRVLYPLLAHTQLKYKREELKKVL-NI Aurde31 LAVGILYEVCRVQKFDITGLRIFDDRFIETLFDLVEETRDETLNYTIKLILALNEQFMVANRVLQILVARKTFAENIIFMLNRAMQLLVLKILYLLFTTSTHEYFYTNDLCVLVDVFLRELADLEALRHTYLRVLSPLLTNTQLRYKRGQIVRTLQAL Batde5 VTVLLFDHLCQVHEMSLHELDIIDTQLLNYLCELVESSRNESFNYVIRLLITLNGQLMKMDRFLRVLEQRKTLTENLIFVFNRALQLSITILLIGIFQYPTRNLFYTNDLTVILDVGIREIQRVEELLHALVKLL-PLVVVSGASHK--QVVNVLNKL Botbo1 LAVELLYDLCRLQKLSTEELQIFDDRVIDLLFELVEHTREEELNYVIKVLVALNEQFMVANTVLMVLLRRKTFAENLIFMLNRAMQLLVLKMFYLLFTTGTQEYFYTNDLCVLVDVFLRELVDLESLRHTYLRVLHPLLTNTQLRYKRAQIRNVLQSL Botci1 LLLELLYEMSRMQRLSFEDLGQVDDEFIICLFEIIEELSNDPYHYVIRVLLVLNEQYMVANRVVKILSHKMTFGENIILLLNRELQLLILKLLYLLFTTATYEYFYTNDLRVLLDVIIRNLLDLVSLRHTYLRVLYPLLAHTQLQYKKHEVVKVL-SI Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 LLLQLLYESSRIQRLTYDDLMAVNDAFILYLLGIIEGASDDPYHYVIRVLLVLNEQYLVANRVIKAISTHKTFGCNLILLLNRELQLLILKVLYLLFGNSTAEYFYTNDLHVLVDVILRNLIDLNALRHTYLRVLHPILLHSQISYKRDELLRLL-RL Coere1 LAMSLMFEIAQAVRLSASDVACVTEELLQFLLDYVERMRSEVYNNATKLVLALDEQLHVKPSVVAMLAKRKTFVENLVFLLNRETQRLILGMLAGILTDDTAQILYTNDLNVLTDIVIRELSNLQQQRRVYLQVVCALLRNPAYLHRLPDIELCLVTL Conco1 PAVQLLGLICSKSTLNSIDRSYLDKKLVDCLFDMVEFLRDDILEELIQLILVIHNQFTLLTIVLLALEAKKTFGEALIFFLNRSVQSATLKFISDIFNYPTSNYFYTNDLYVLVDIIIRQLNDLDQVKLDYLNCLYSLLPNSQYSYKCNEIETLLQHL Conpu1 LGVKLLYEVCRVQKLSIQDLRVFDDSFINFLFDLVEETRDETFNYVIKLIVALNEQFMVANRVMNILMSRKTFAENLIFMLNRAMQLLVLKLLYNLFTTGTSEYFYTNDLCVLVDVFLRELVDLESLRHTYLRVLNPLLTKTQLRYKRPQVVMALESL Copci LGIKLLYEICKVQKMTAVDLKIFDDSFIDYLFELVEQTKDDAFNYVIKLIVALNEQFMVANRIIRILVRRHTFGENLIFMLNRAMQLLILKLLYVLFTTSLAEYFYTNDLCVLVDVFLRELSNLESLRHTYLRVLHPLLTKTQLRYKRPHIMSLLESL Croqu1 VLAGLLYELCRVQKLEPGILEAVNETLIGNLFELVELTRDETFNYLIKLIIALNEQFMVFNIVIRTMKARKTFGENLIFILNRSVSLLILKILYLLFTTGTHEYFYTNDLCVLVDVFIRELSDLEGLRHTYLRVLHPLLTNTQLRYKRREIRHVLLSH CryneH991 PATCLMYEVARVQKLTSSELAQFDDQFIDHLFDLVETTWDERLNYVIRLIVALNEQFMVA-----------------------TMQLLILKILYLLFTTGTQEYFFTNDLKVLLDVFIRELVDLEALRHTYLRVLYPLLNHTQLRYKRPQIKLVLRSL Crypa2 LLLELIYEMARIERLRVDDLLCVDDNFIIYMFHLIEGLSNDPYHYIIRVLLVLNEQYMVANRVIKILSLHRTFGENIILLLNRELQLLILKLFYLLFTTATYEYFYTNDLRVLLDVIIRNLLDLMALRHTYLRVLYPLLAHTQLSYKRQEILKVL-QI Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 PYLELVFKICQGLELKPEQLDIINAEFLKFAAKHLNAETNQ-LNYKFRLLLILNEQYMVRNQLFCVLVENQNFMEVLVLNFNREVQILMLKALYVVFTTSTCQLIYLNDLEVIMDIMIRELCNLGILINTYLRVLYPMLLFSNLNYKVDSLRSILRYL Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LAVGILYEVCRVQKFSLADLRVFDDAFIDFLFDLVEQTRDEALNYLIKLIVALNEQFMVANRVLRVLMLRKTFGENMIFMLNRAMQLLVLKILYLLFTTGTTEYFYTNDLRVLVDVFLRELVDLESLRHTYLRVLHPLLTRTQLRYKRPQVVRTLESL Fusgr1 LLLQLMYEMSRMERLRVDDLTMVDDEFVHYLFALIEELSHDPYHYTIRVLLVLNEQYMLANRIVKCLSLHRTFGENIILLLNRELQLLILKLLYLLFTNATYEYFYTNDLRVLLDVIIRNLMDLISLRHTYLRVLYPLLAHTQLSYKQDEVLRVL-NI Galma1 LCVKLLYEVCKVQTLSVQDLKIFDDSFLDYLFDLVEQTKDDTFNYVIKLIIAMNEQFMVANRVIRVMMRRKTFGENMIFMLNRTVKLLILKILYVLFSTGTSEFFYTNDLCVLVDVFLRELADLESLRHTYLRVLHPLLTKTQLRYKRPQILVALESM Ganpr1 VSSSTPYRILRIRKLAPEELALFDETFLQNIFDLVEATRDEC--YTIELIVSLNEQFLVANLVLSTLKSRKTFAENLVFIFNRAIQLQLLKLFYVLFADTLSHFLYPNDLRVVLDVILREVPNLAALRAAYLRVLKPLLFQTGLVYKLEEVKSAALAI Gloin1 ISIKLLFEICRVQRLSSDELDLIDELFLNHLLDLVEKTRDETFNYVICLILSFNEQFMLANTVLRVLGERKTFSENVIFMLNRTIQMLILKLLYEIFTTETYEYFYTNDLRVLIDVFIRELYDLEALRHTYLRVLYPLIINTQLSYKQHQIYSLLLDL Hisca1 LLMNLMYEMCRIQRIKIGDLVLVDDDFVKHLFEIVEELSDDPYHYVIKILLVLNEQFMVSNKVIKVLSMFKTFGENIILLLNRELQLLTLKLLYLLFTTPTYEYFYTNDLRVLVDILIRNLLDLTALRHTYLRVLYPLLAHTQLRYKRDELRKLL-GI Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LGVKLLYEVSRVQKLSVQDLRIFDDSFLDYLFDLVEETRDETFNYVIKLIAALNEQFMVANRLIRVLMRRKTFGENMIFMLNRAMQLLLLKILYVLFTTGTSEYFYTNDLCVLVDVFLRELVDLDSLRHTYLRVLHPLLTKTQLRYKRSQILVALESL Lenti61 LSVQLLYEVCRVQKMSLQELRLFDDSFIDYLFDLVEQTRDETFNYVIKLIVALNEQFMVANRVLRVLISRPTFGENLIFMLNRAMQLLVLKLLYLLFTTGMAEFFYTNDLCVLVDVFLREICNIESLRHTYLRVLHPLLTKTQLRYKRPQIVQTLESL Malgl1 HAIHILYEILCSVRWRAQDMRVLTPHFVDHLFVVMET--SDSSEYCMRVILALHDQCMMSTTLLPHIEQQKTCSENLVFLLNRTFHLLVLKLLGAIFCLETASYFYVNDLKVLVDIFLRELSDLDLLRQAYLCVFHALLTQTQLCYKRTHITRLLTNM Mellp23 VLAGLLYELCRVQKLDADVLEAFNEDLIGNLFELVELTRDETFNYLIKLIIALNEQFMVSNIVIRTMKQRKTFGENLIFILNRAVSLLILKILYLLFTTGTHEYFYTNDLCVLVDVFIRELSDLDSLRHTYLRVLHPLLTSTQLRYKRREIRHVLLSH Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 IAMALMYEMCRIQTLKASDLALADETFLNYLLDLIEHTRAEQLNYAIKLLLVFNEQYMLHNPLLTVLADRATFGENLIFMLNRALQMLILKILYLLFTSSLYEFFYTNDLHVLVDVVIRELWDLESLRHAYLRVLGPLLTNTQLKYKRAEIVRLLREL Mucci2 ASFALCFEMCKLAKLEHADLVLLDTSTVNHFLDLVEETRDESFNYVIRLILVLNEQYMMSNLVLDVLSQRDTFSANLMFMLNRSVQMLILKLLYGIFTRSLYEYFYTNDLYVLVDITLRELCDLQTLRDAYLRVLEPLLENTQLRYKKQETYKTLQSL Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LLLELMYEMSRIEKLPHQDLAQVEDEFVIYLFQLIEAFSDDPYHYVIRVLLVMNEQYMVANRVVKVLSLHRTFGENIILLLNRALQLIILKLLYLLFTTATYEYFYTNDLRVLLDVIIRNLLDLNTLRHTYLRVLAPLLSHTQLSYKRDQILSLL-EI Orpsp11 --------------------------------------------------VVLSNQIEHKNNILTVLEKRKTLSENLIFILNRTVKLYILKFLDLIFSTSLDKFFYTNDIPVLLDVTLRELWNL---------------------------------- Pench1 LLMDLVYEMSRIQRVKIEDLVLVDDDFIRCLFDIIEDLSTDPYHYVIRVLLVLNEQFMISNKVIKVLSMYKTFGENIILLINRELQLLTLKLLYLIFTTSTYEYFFTNDLHVLVDILIRNLLDLSALRHTYLRVLYPLLAHTQLRYKRDGLRRLL-SV Phybl2 VLLSLTFEMCKVTKLRKLDRDMITDSLLNYMFDIVESTREESFNYVIRLILVFNEQFMMSNLVLKVLSKRNTFSENLFFMLNRSVQLLILKLLYGVFTESLHEYFYTNDLFVLVDIILRKVCDLEALRDAHLRVLRPLLVNTQLRYKRAEIHRLLCSL Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 LAVRLVYEVCRVQKLSVQDLRIFDDAFLDSLFDLVEQTRDESFNYVIKLIVALNEQFMVANRVLNVLMRRKTFGENMIFMLNRAMQLLVLKILYLLFTTGAAEYFYTNDLCVLVDVFLRELVDLESLRHTYLRVLHPLLTKTQLRYKRAQIVRSLESL Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 LLSGLLYELCRVQKLEDGTLGLFSEQLIDNLFQLVELTRDETFNYLIKLIIALNEQFMLANIIIRTMKLRKTFGENLIFILNRAVSLLILKILYLLFTTGTHEYFYTNDLCVLVDIFIRELSDLNDLRHTYLRVLHPLLTHTQLRYKREQIRHVLLSH Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ILFSLCFELSKLDKIEKYDLDLVDTSLINQLLNLVQETRQESFNYVIRLLLVFNEQYMMSNLVLDVLSQRDIFSANLIFMLNRS-----------------------------IDIILREVCGLQTLLEAYLRVLEPLLENTQLNYKKNEIYRVLQQL Rhoto1 AATAVLYEMCRVQKLTLDELSDFTFDFISHLFSLVERTRDETFNYLIKLIIALNEQFMVCNTVLEVLKEKKTFGENIIFILNRAVSLLILKILYLLFTTGTQEYFYTNDLCVLVDVFIRELYNLEGLKHTYLRVLHPLLTNTQLRYKRQELRRVLECL Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LSVKLLYEVCRVQRLSLSDLRIFPSAFIDFLFDLVEQTRNDAFNYIIKLIVALNEQFMVANRVLSVLMRRKTFGENVIFMLNRSTQLLLLKILYLLFTTGTEDFFYTNDLFVLVDVFLRELGDLESLRHTYLRVLHPLLTKTELRYKRAQLAYLLESI Schpo1 YALFLVYYICRSRRLSPTDLVAIDEYFLVNLFKTSEEAWEDMDSFCVLTLLSINEQFMLVNGIMDLLSSSGIYSEGLVFTLNRESRMLILKQLFLLFTTATYEIFYTNDLNVLIDIFIREINNISDLRYAYLQVLIPLLENTQVRYKTKCIVDAVNNV Sorma LLLELMYEMSRIEKLPHQDLAQVDDEFVIYLFQLIEAFSDDPYHYVIRVLLVMNEQYMVANRVVKVLSLHRTFGENIILLLNRALQLIILKLLYLLFTTATYEYFYTNDLRVLLDVIIRNLLDLNTLRHTYLRVLAPLLSHTQLSYKRDQILSLL-EI Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 MAALLMCEICETRELSLSDLETFDASFLNNLAEMIEQTGNEEENYLVRALLAIHDQFAQKNRVIEVLQKRKTLSENFIFIFNRERRIIMARFLEIVLSSSARNLWYTNDLGIILDVVIRETNNVEMLHHSYIRLLPLLLRHPNVTRRKQEVEKQL--- Sporo1 AATAVLYEVCRVQKLSPEELAYFTFPFISHLFSLVERTRDETFNYLIKLLIALNEQFMVSNFVLEVLKERKTFGENIIFILNRSVSLLILKVLYLLFTTGTQEFFYTNDLCVLVDVFIRELHDLEGLKHTYLRVLHPLMTNTQMRYKRPELRKILETL Stehi1 LAVRLLYEVCRASKLNKQELGVFTDDFIDRLFDIVEQTRDETFNYVIKLIVALNEQFMVANRVLRVLIRRQTFGGNMIFMLNRAMQLLVLKILYLLFSTGTSEYFYTNDLCVLVDVFLRELVDLESLRHTYLRVLHPLLTKTQLRYKRPQIVRTLESL Tapde11 LALTTLYEMCRMQKLSEADMHCFDEEFIWFLLRSVEISRDDPYSYCIKVIVSLNEQFMVANSIVKVLSDHKAFGENLIRMLNRELQLLILKQLFLLFTNATYEYFYTNDLHVLIDVFIRELYNLEALRHTYLRVLHPLLIHTQLRYKATEMV----NL Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 PATNLMYEVCRVQKLDAQELAQFDDTFIDHLFDLVEVTRDERLNYVIKLLIALNEQFMVANRVLVVLMRRKTFGENIIFILNRAMQLLILKILYLLFTTGTQEYFYTNDLRVLLDVFIRELVDLEALRHTYLRVLYPLLNHTQLRYKRAQIKLVLKSL Trire2 FLLQLMYEMSRVERLSPEDLALVDDDFIHLLFGLIEGVSNDPYHYTIRVL-----QYMLANRIVKCLSLYRTFGENIILLLNRELQLLILKLLYLLFTTATYEYFYTNDLRVLLDVIIRNLMDLMSLRHTYLRILYPLLAHTQMNYKKDEILRVI-RI Umbra1 VILMLMFEMCKVAKLSKGDLEHISPAFIHYLLDIVENMSEELLNYAMRLILVFNEQFMMQNQILRVLRSKKTFSENLIFMLNRAVQMLILKLLYLIFTTELFEFFYTNDLCVLVDIVLRELCDLEA---TYLRVLNPMLVNTQLRYKHQQIHRILCAM Ustma22 KAVRMLYEVCRVQKLEASHLKAFDERFIHHLFDLVEETRNEDFNYLIKLLVAMNEQYMVSNLVLSVLQQRKTFGENLIFMLNRAMQLLVLKLLYLLFTTETACYFYTNDLRVLVDIFVRELNDLESLRHTYLRVLHPLLTNTQLCYKRPQIRRLLRGL Walse1 TVICLLYEISRAQKLSDEDLATFNSSFLDHLFDLVELTRDECFNYIIKLLTSLNEQYMIRNLVLNVLTRRKTFGENLIFILNRAVKLLVLKILFLLFTTGTENYFYTNDLKVLVDVFIRELADLEGLRHTYLRVLYPLLNKTVIKYKTLEVHSSLCAL Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3668.fasta_al_trimmed; alignment length = 157] Allma1 MSLDINLAHALLNDRIP-YVRHLVSNLRFGSNPPDITLLSVVDDVQIHVHVAY-RGDVAVDSTAQLGAPLPGGGGGSLWLPVQMHLRGCHL-DALLAVAVSRVAWCLLIKALNIETSVGDSKQMLHNVTKVEKFLVDELHRLLDQECVWPNYQTVLF Ashgo11 MSFDININQRALNEHLPSYVSNIMTDFKLGTIPPRITLKQIDNDVQFLMEVDY-KGDMLIELSAELVLNYPSPNFMQ--LPVKLTISDIGI-HSLCLVAYRQLFISFLIRSIKIQTEIGPEGTILRSVGKLEQFLSDVFKNLLRKEAAWPSWINLDF Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 MSIELDLATRLLNRTIPSFIGPVVTALDFGTVAPDIEIIDVRDNLQLHLYIRH-DSDMRITVTTSLLINYPSPMFMA--LPIKLSVTGLIF-TGQVVVAYKRMHICIVLPSIFIESEIGQDSHVLRNVTRVEKFMQEVIRKTIEDELVFPNFHTLVM Batde5 MSFIIDEAERLVNDHFPSFLGKVVMQLDFGDIPPEVTIEDICDDAQLELNVRY-HGNMRLSISTELIVNQPTPAFMV--LPLALTLTGFSF-DGTAVIAYYAINFCFKLQDMTIESEIGDNKQVLKNVEKIERFIVQQLKSFFNDFLVFPNFHSIYL Botbo1 MSIDLDFCDRLLNTHLPSFIGPIVTSLSLGSSSPDVEVVDVRDDLQVHLRIAY-TSDVRIRLTTSLTINYPSSMFMS--LPVSLAITGLVF-RGELVVAYKRIHLCILLPTILIESEIGADKHMLRNVSRVERFIQDVMRKTIEEELVFPNFHTLIL Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 MSFDININQSILDQQFPSFISNLVTDFNLGEIPPEVTIRHIGDDIQLIVEINY-KGDMHINLLVNLLVNYPSPNFIS--LPIKLHITDIVI-HSIATIAYKSVFLSFLVKKIKIESEIGEENNILRNVGKVEKFLVEQLRNILRDEIAWPSWICIDM Cangl MSFEINLTSNILNGYFPSYVRAILVDFGFGKIAPNITLREISSDTQFLIEFEY-KGDMSLTLTAELVLNYPVERFMT--LPLKISISNIGL-HSLCLVSYKQVFISMLIRSMKIETEIGDDGSTLRSVGQLEEFIVQKLKDFLRKELAWPSWVNLDF Capow MSITFDHADLLLNAKLPDLLGPIVTEVALGSTPPRVDIEALSDAVQLQFALAY-TGDVTITVETDIRVNTPVPGFIS--LPITLGVTGLNV-SGRVIAAHKTVCVTVLLADLRLKTTLGDDKKLLKHIEQLESFIVRQLRQVIHEKVVYPRFIKVLL Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 MSFSIYVAQSVLNKFFPSFLGEIVEELDFGSVPPYLEIQDLTEDIQLRAKVEY-CGDMTIVLRMELQLNYPATQFVS--LPVKMTITKIEF-AATLVVAY-RVNVCFLLDHFSIRTEIGDGQHVLKNVEKLESFITEQLRNAIDDDFVFPSYHSFEL Conco1 MSFDINYTKSILNKKFPKFLGPMVTEFNLGTIPPNIVLKDMMEDLQLLFSLEY-DGNISFTISSSIQLSLPFGSFMH--LPMKFKISGFQF-NTNFLIIYQQVKFTLFLKNLKIESEIGDNKQVLKNVDKVEKFILEQTRKIILNHFTYPKFFDFNL Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci MSIDLELANYLLNRQLPSFIGPVVTSLEFGSASPDVELVDLRDNLQLHLQVNW-HSNLRITITTSLLINYPSPMFMS--LPIKLSVTGLVF-NGELAVAYRRVHVCILLPSIFIESEIGQDKHVLKNVTRVERFIQDVIRKTVEEELVFPNFHTLVM Croqu1 MSFEIDLATTLLNRILPSFLDPIVQSIDFGDNAPEVQLIDIRDSLELHLKVTY-SGNMRIDLSTALVLNYPSPLFMS--LPVKMRVVGFVF-AAEVVLAICRCHCTIFIPEMLIHTEVGNDKHVLRNVGKVERFLVETLRRIICDELLFPTFQTFDW CryneH991 MSLDINLSDSLLNTQLPSFIGPIVTAFDFGKAAPDLEIKDIRDSLQLHLRLSH-ASDLHLTLLTSLQVNYPSALFMA--LPLKLSITGFQL-NADIVMAYNRVHLTVVLSNLQIESEIGHDAHVLRNVGKVERFIVDVVRKTLVDELVFPNFHTVAL Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 MSFDINSRSSLLNEKLPKYMKDLIVEVNLGSKSPKLTIRDIDYDIQFTMDLEW-NSNIYIEVTCSLMVNYPSPGFIT--LPVRLKISDLSI-HSLAVSAYHRVFVSFLIKNMKIEGELGDNGSVLRNIGKIEKFLLSALRKVSVNELAWPSWIEIDM Dicdi MSLKIYHSIKLLNERIYDMVGEMITNLSLGSKPPKFEIIQISDGIELRAKIGY-DGDAYIGIQAEFKVNLPTPNFIS--FPVNVKVSNPIF-SG--IATVDKVCFCFLLKDVKFETQLGDAQQVLVDLDKLQNFIVDLIKTYLKKYLVFPNKMTIPL Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 MSLDLALAQKLLNKHLPSFIGPVVTGLDFGAVCPDIEVVDLRDNIQIHLRVLH-HSDLRISITTSLLINYPAPLFLS--LPIKLAVTGLEL-TGEVVLAYRRVHFCLLLPSIFIESEIGQDKHVLKNVTRVERFIQDVIRKTVEDELVFPNFHTIIL Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 MSIDLEFASYLLNRQLPSFIGPVVTSLEFGSVAPDVELVDLRDNLQLHLHIDW-HSNLRITLTTSLLINYPSPMFMS--LPIKLSVTGLVF-NGEVAIAYKRVHLCILLPSIYIESEIGQDKHVLKNVTRVERFIQDVIRKTIEEELVFPNFHTLVM Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 QQQRLRIPLHL------------YKDY-------NIQIDDQTQ--QIHIEVSY-KGNMKMVICTELYMNYPSLMFMS--LPVRLTITGFEF-SATAVVAY-RVNFCFL-KEVYIESEIGDEKQVLKNVGKLEKFIIDQLRKIIDEDFVFPSYHSIEL Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 MSVEIDVNQGVLNSRLPSYVNNLVTNFDLGTMPPNVILKQMDDDVQLLVELDY-KGDMSIELSADLVLNYPSPQFMI--LPVKLRISDIGM-HCLCLLAYKQLFISFLIRNIKIHTELGQEGSVLRSVGKLEEFLVDLFRNLIRKEAAWPSWIDLDF Lacbi2 MSIDLELATYLLNRQLPSFIGPVVTSLDFGSASPDVELVDLRDNLQLHLHVNW-HSNLRITLTTSLLINYPSPMFMS--LPIKLSVTGLIF-IGELAVAYRRVHLCILLPSIYIESEIGQDKHVLKNVTRVERFIQDVIRKTVEEELVFPNFHTIVM Lenti61 MSIDLELASTLINRQLPSFIGPIVTSFDFGATAPDVELVDLRDDLQLHLHITW-HSNLRLTLTTSLLINYPSPMFMS--LPIKLSVTGLLF-NGEVVVAYKRVHLCI-LPTIYIESEIGQDKHVLKNVTRVERFIQDVIRKTVEEELVFPNFQTFVL Malgl1 MSIELDFADSLLNAALPTFLGPTVQAIELGSEGPDVQVIHIGHSLQMHLSVQWLTSTMRLSLTTSLKIAYNNDTIMS--LPISLVVTGMEL-FAQAIVALRCVYLSLSLPFLALESKVGEAKHVLENVGKVERFVGDMLRQWLEDELVYPHFYTLYL Mellp23 MSLEIDLAKTLLNRILPTFLDPIIQSVEFGDSSPEIQIIDIRDSLELHLRVTY-SGNMRIDLSTALVLNHPAPLFMS--LPVKMRVMGFVF-TAEVILAISRCHCTIMLPEMLIHTEVGNDKHVLRNVGKVERFLLDTLRRIICDELLFPYFQLIRH Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MDLDLDLSFPLLGQILPDLSGMVIPSTPRGFESPTLAF-----DIQLLLAVHY-QGQMGFTVETELLLNYPTYAFLT--LPVKLVITGFSF-KTKMLMGYDHVNVSFLLSNVRIESQVGDKQAVLKNVGKIERFVVEQLRKFITEDFVYPSYHSIEL Mucci2 MSLDIDLAGHVLNKHFPSFIGDIVKDFQWGNEAPQIEITNITEDFQVHMLISY-KGDMSMTVITELRMNYPSVMFMS--LPINLKVRSVEF-EATAVVAYQRVCVSMLDRDVHIETVVGDQKQVLKNVGKIEKFIVDQLRKMLDDELVFPSYQLIQL Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ISFDFNTSENETNTDNNKFIESILPITSTLNNDSDISSEDVSSDIQVELEVIY-HGNLKLTVSTALILNKPTPAFMT--LPIKLALKGISF-KGVAVIAYKQINFCFKIEDIRLESELGDNKQ---------------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 MSFEININESLLDRQFPSYIANLVTNFSVGDIPPEITIRHIGDDIQIIAEIEY-SGNLHVDLIVNLLVNYPSPNFIS--LPIKLHITDIVI-HSIATIAYKAVYFSFLVKKIKIESEIGEENNVLRNVGKVEKFLIEQLRNIIREELAWPSWICIDM Plicr1 MSIDLELSSTLLNRQLPSFIGPVVTSLDFGSASPDVELVDLRDNLQLHLHITW-QSDLRITLTTSLLINYPSPMFMS--LPIKLSVTGLLF-TGELAVAYRRVHLCILLPNIYIESEIGQDKHVLKNVTRVERFIQDVIRKTVEEELVFPNFHTLVM Polpo MSLKIYQSNKALN-RIPDIIGKFITSLSLGSKPPTFEIISIADSIEARVKFSY-DGDAHFMLEAELLVNAPTPKFII--FPISIKVSSPHI-SG--IASVKN--------------------------DELREIIA--------KRMVYPNRITLSL Pucgr2 MSIEIDIAEKLLNGLLPDFLGPLIQSIDFGDIAPEVEIVDIRDSLQIHLRLTY-DGNLRLRFSTALVLNHPAAEFMS--LPLRATVVGVGF-DAEIILAISKFHLSLLLPHLFVETEVGNDRHVLRNVGKVERFLTETIRSLICEEFLYPTFQTFEW Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 MSIDLDLTQSALANAFPDFLGPLVTTFSFGDTEPQIELLDIRDSFQLHLRVSY-SGNLSLGISTSLLINYPSPGFMS--LPLELTVTGLAF-EGVLIVAFRRLHLSLVLRSAQVESEVGQDKHVLKNVGKVEKFVLEVARKTLENELVFPNFQSVLY Rozal11 MSCKLFINQSLLNEYFPDFIGDIIRAIFLGEESPDIEILDITDQFQVNVSLDY-DGNAGVTIETE--------------FPLQL--------------------------DIMMDSDVGE--QVLKNTGKIEKFIVENINSI--PQLPFDSV----- Sacce1 MSFDINLNDLILNSYLPSYVSNLVLDFDLGKVGPAITLKEITDDIQFLLEVEY-KGDLLVTIGADLVLNYPVEKFMT--LPVKLSISDIGL-HSLCIVACKQLFLSFLVRSMKIETEIGEQGSVLRSVGELEQFLFTIFKDFLRKELAWPSWINLDF Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MSIDLDLAQHLLNRQLPSFIGPVVCSLDFGSAAPDVELVDLRDNLQLHLYVTW-NSDLRITLTTSLLINYPSPSFMS--LPIKLSVTGLVF-NGEVAVAYRRIHLCILLPSIVIESEIGQDKHVLRNVTRVEKFIQDMIRKTVEEELVFPNFHTLVM Schpo1 MSIDFDLEAKVLEGQVPSYIKHLVVDFHFGKVSPQITIQEIGDDFQVTAHVSY-DGDANLSLEAVLSMNYPNSEFAV--LPFKLSFIRISI-DAIAVLAKKRTHLCFVIRDLTVESIIGENKQLLKNVAKVEKFVSEKVKRIIEDELVWPSYITIE- Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar MSLELNEHSKLLNEKLIAGLGNVIHDLDLGDRAPIVELIDISDCVQVRVRVAY-QGSAVLRVSADVQVNTPSPAFVS--LPFELTTRALHI-DAE-IIAYKDIRISLLLVDVSFDANLGDNQSVLRNVEKIQNFIVVATRTLMAKYLMYPRSLVFPF Spipu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 MSIDLDLSASLLNTHLPSFIGPIITSFDFGSQPPDVELIDLRNDLQIHLHITW-PSNLRLTLTTSLRINYPSPMFMS--LPIKLSVTGLLF-TGEVAVAYRRVHLCILLPNVFIESELGQDKHVLKNVTRVERFIQDVIRKTVEEEFVFPNFHTLVL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MSLDINFSTILLNRQLPSFIGPIIVDLKFGTTGPYVEIRDIRDSLQLHLHLHH-NSDLVLTLQTSLQVNYPSLGFMS--LPLKLSIVGFTL-DADVVLAFNRVHVCIVLPSLIIESEIGDDSHVLRNVGKVERFISDVVRKTLVEELVWPNFHSIQL Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 MSLDLDLSDRFINRALPSFIGDIFEKLDFGSDSPDVAIRSITDSLQMRLSLVWPTTTFRLTITTSLLINYPSAAFMS--LPLTLSVTGFMM-RCGVIVALQRAHVCLVLPQLTFESEVGQEKHVLKNVGKVEKFIAEVIRKGLEDELVYPNYYTIDL Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 MSFDIHLNESILNTYLPSYVCNLILDFSLGKTAPNITLREISDDIQFLVEVEY-KGDLLVTLAADLVLNYPSDNFMT--LPVKLTISNVGL-HSLCLVAHKHLLISFLIRNMKIETEIGQEGSVLRSVGRLEQFLLEIFKDLLRKEVSWPSWIELDF [Cluster3678.fasta_al_trimmed; alignment length = 79] Allma1 ------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------- Aspfu1 KCTVYVGGLLAEAFVPFGEVVDITLPHRGFGYVEFDLPEDAAEAIDNMDGSELGRTIKVAAAKPKTAIWEQEGYLAKYA Aurde31 KKTVFIANVLLEGFSTFGDVVDVQLPHRGFAFVTYAAAADAQDAIDNMDLNVFGKVIKVNIATSNRPVWETEEWLKTYG Batde5 ------------------------------------------------------------------------------- Botbo1 KRTIYVGGLIRVVFATFGDVIDIQIPHRGFAFVTFSSAMDAQDAIDNMDLNEMGRVLRVNLARPNRAIWESEEWLKANA Botci1 KATVYVGGLLEAAFLPFGEIADVSIPHRGFGYVEFEDPEDTKDAIDNMDQSELGKVIKVNAAKPKTALWEQEGWLAENA Caeel ------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------- Catan2 ----YTGGLLENLFIAFGDIVNVDVPNRGFAFVTFEDPEDALAAIDNLHLSEIGRTIKVNLANATKAGMFTLDYLSPVR Cioin NASLFVRNILRREFVRFGPVSDVYIPPRGFAYIQFEDTRDAEDALYAMDRKWIGRYIEVQFAAGRSRVYREKSYTPDRR CocheC53 KATVFVGGLLFHAFLPFGDIVEVNLPHRGFGYVEFESAADAVDAIDNMDRSELGSVIKVAPAKPKTAIWEQEGWLAKHA Coere1 ------------------------------------------------------------------------------- Conco1 TNKLFFGNLVHDHFSPFGEIVEISIANRGFGFVTYEREESAKDAIQNLDGSEFGRKLGVKAAEAR-------------- Conpu1 KKTIFIGGILYETFSPFGDIIEVQLPHRGFGFVTFGSPADAQDAIDNMDLNELGRVLKVNLARPNRAIWETEEWLQRYA Copci KKTVFIGGIIYETFSTFGDILEVQIPHRGFAFVTFSSPADAQDAIDNMDMNELGRVLKVTLAKPNRAVWESEEWLKQYV Croqu1 RKTIFVGNLLHEAFMPFGIITDIHIPNRNFAFITFSNASSAVDAIDNMHLNALFKILKVNLAR-KKAIWDDEKWIKEHA CryneH991 KSSVYVSGFLLQAFVTFGDIIEIKIPHRGYAFITFSSAADAQEAIDNYDLNQLGRFLKCSLAQPDRAIWETEEWKAEHG Crypa2 KATVFVGGLIHDAFLPFGDIADVSLPHRGFAYVEFEDAEDAKEAIDNMDQAEFGRVIKVTPAKAKTAIWAQESWLAKNA Debha1 DSKLEVSNLVESIFLPFGNIVSIDIT----ALVHYEESEDCSSAIANMNGFDCGTYLTVRTSRN--------------- Dekbr2 ------------------------------------------------------------------------------- Dicdi KNVLYVGGILRAAFIPFGNINDVILPLKGFGFIDFELPEDAADALDNMHESEIGRVIKCSIAKPNKAVWSSDDYHNE-- Dmel ------------------------------------------------------------------------------- Enthi ---IYVSGLLYEVFLPFGEITDIQLPNKGYGFVVFEDEEDASQAILNMNKAELGKTLTVSSSR---------------- Falba ------------------------------------------------------------------------------- Fomme1 KKTVFIGGIIYESFSTFGDILEVQIPHRGFAFVTYTSSGDAQDAIDNMDMNELGRVLRVNLARPNRPIWESEEWLKQYA Fusgr1 KATVHVGGLVLDAFIPFGEIVEVKVPHRGFAYVEYEDAADAKEAIDNMDQSEFGKVLKVSQAKAKTAVWEKEGWLAEHA Galma1 KKTVFVGGILYESFSTFGDILEVQIPHRGFAFITYTSTLDAQDAIDNMDMNELGRVLKVNLARPNRAIWETEEWLQANV Ganpr1 ------------------------------------------------------------------------------- Gloin1 RTTIYVGGLLHAAFIPFGDIVEIQIPHRGFGFVEFEEASDAQASIDNMNLSELGKVIKVNLARP--AVWSEDAWLQKYA Hisca1 KNTIYVGGLLTEAFLPFGEIADISLPHRGFGYVEFEDPQDAKEAIDNMDQSELGRIIKVAAAKPKTAIWQQEGYLAQHA Klula1 ------------------------------------------------------------------------------- Lacbi2 KKTVFVGGIIYQSFSTFGEIVQVQLPHRGFAFVTYGSSSDAQDAIDNMDMNELGRVIKVNLARPNRAIWESEEWLQQHV Lenti61 KKTIFVGGIILENFATFGDVIEVQLPHRGFAFVTYTSPADAQDAIDNMDLNELGRVLRVNLARPNRAIWESEDWLRKNA Malgl1 ---------LLSIFSTFGDISDVQLPHRGYAFITYTQEEDAEDAMDNMNLNELG------------------AWLQEH- Mellp23 RKSIFVGNILQAAFQPFGVITDLHIPNRNFAFITFSDASSAVDAIDNMHLNTLLKILKVNLAR-KKAIWDDEQWIKEHA Mnele ------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------- Morel2 KSTLFVGGLLHAAFIPFGDITQIEIPHRGFGFVEFDLAVDAQAAQDNMHLSELGRTIKVNLAKPEKAIWADEDWLKENV Mucci2 ------------------------------------------------------------------------------- Mydma GVPVLIKNILIEKFSTFGQILKMKTS----ATLFYMSPADAQRAISNMNGARLSKVICAKLDNPSHATYRN-LFIKS-- Neucr2 KATVHIRGLIHDAFIPFGEIADISLPHRGFAYVEYEDEEDAKEAIDNMDQSELGRVIRVSAAKIKTAVWEQEGWLAENA Orpsp11 ------------------------------------------------------------------------------- Pench1 KSTVYVGGLLAEAFVPFGEVVDISLPHRGFGYVEFDLPQDAKEAIDNMDGSEIGRTIKVAAAKPKTAIWEQEGYLAKHA Phybl2 ------------------------------------------------------------------------------- Picst3 ------------------------------------------------------------------------------- Plicr1 KKTVFVGGIIYESFSTFGDIIEVQLPHRGFAFVTYSSSGDAQDAIDNMDLNELGRVIKVNLARPNRAIWESEEWLQQNA Polpo KKTLYVGGLLRGAFIPFGEIRDISLPKRIVLTFKFDTREDALDAVDNMHDSEIGRTINCTIAK-NKSQMDHQQHFQPYL Pucgr2 NKTIFVGNILHSSFSPFGNIRDIQIPNRNFAFITFQDQIEALDAIDNMHLNLLEKILKVNLARNNRAIWDDETWIKENA Punst1 KKTVFIGGILLDTFSSFGDVIEVQIPHRGFAFVTYTSAEDAQDAIDNMDLNELGRVLKVSLARPNRAVWESEEWIKQYA Rhior3 ------------------------------------------------------------------------------- Rhoto1 NSTIYVGGFLHSAFLPFGEILDLSLPHRGFAFITFANAESAIDACDNMDRNSLGRVLKVNKAKP-KPIWAQEEWIAEHG Rozal11 ------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------- Schco3 KKTIFVGGLLFETFSTFGDVVEVQLPHRGFAFVTFTSSADAQDAIDNMDLNELGKVIKVNLAKPNRAVWETEEWLQTHL Schpo1 KATVHVGNLLYNAFIPFGEIISVALHDRSYAFVEFDEPEDAKEAMENMNYSILDRCIRVSPA--NFALSAEETAVPDIA Sorma KATVHVRGLLHDAFIPFGEISDISLPHRGFAYVEYEDEEDAKEAIDNMDQSELGRVIRVSAAKIRTAVWEQEGWLAENA Sphar ------------------------------------------------------------------------------- Spipu1 ------------------------------------------------------------------------------- Sporo1 QNTIYVGGFIHAAFHPFGEILDLQLPHRGFAFVSYSTGESALDAIDNMHRNVLGKPLKVNRAKP--------------- Stehi1 KKTVFIGGIILEAFQTFGDIIEVQLPHRGFAFVTFSSSGDAQDAIDNMDLNELGRVLKVNLARPNRAVWESEEWLKQYA Tapde11 KTTISVSNAFISYFIPFGEIIEVGDP------IEFEEAADAAAAQDNMDGAELGQTVTVTLAPPRVPLWEQEGFIQKYL Thetr RRHLFVAGLLRAAFIPFGPVLSVELPHRGFGFVQFEDAEDAAEAIDNMHMAELGSVLKVNVAKP--AVWESQAYVQSYL Treme1 KSTVYIAGILLEAFVTFGDIIDIKIPHRGFAFLTFANPADAQDAIDNYDLNELGKFLKCSIAQPDRPVWESEEWLKKYA Trire2 KATVYVGGLVFDAFIPFGDIVEVQLPHKGFAYVEYEDSADAKEAIDNMDQSEFGRVIKVSPARAKKAIWEQESWLAEHA Umbra1 ------------------------------------------------------------------------------- Ustma22 SATVYVGNILSSYFAPFGDIVSVSVPNKGFGFVTFSSTDDALDAIDNMHLNAI-RTVEVNLADAARAVWDDEEWMKRHA Walse1 KRTVWVSNVLFGSFSTFGNILDIQLPHRGFGFIEYDNAQDASNAIDNMDMNILGKVIKCNYAKPNRAIWSTEEWIQEYG Zygro1 ------------------------------------------------------------------------------- [Cluster3704.fasta_al_trimmed; alignment length = 48] Allma1 EPSGYLFNEKKRVKDWWEDLYLIFMGGFKPDTNVQTWARKEAERRLAE Ashgo11 ------------------------------------------------ Aspfu1 PPTGWLFGVKKYVKEGWENIWYYGFIGFKPDTSIQTWALEEARRRLEA Aurde31 EPTGYLFGEKKRKRESWETIYYWGMFGIKPDTSIQTWALQEAKARMEA Batde5 ------------------------------------------------ Botbo1 EPSGYLFGEKRRVKEDWENIWMYGMFGYKPDTSIQTWAMNEAKARMEA Botci1 PPSGWLFGVKKAEKEGWENLWVYGFFGVKPDTSIQTWALEEARRRLEA Caeel ------------------------------------------------ Canalb1 ------------------------------------------------ Cangl ------------------------------------------------ Capow YPNGFLFNEKRAKWQDWEPAWYIGMIGYRPDTDPTVKARAIALERLRE Catan2 EPTGYLFGEKKRVKDWWEDIYYWSVGGFKPDTSVQTWARKEAERQMAE Cioin ------------------------------------------------ CocheC53 PPSGWLFGVKAYEKEGWENAMYWGFGGFKPDTSIQTWALEEARRRLEA Coere1 EPGGYLFGRKKLEKEGWETIWGVGFGTYKPDTRIRTWAREEAERQMRE Conco1 EPGGYLFGEKKRVKEDWETIWVWGWSAYKPDNSLSTWAYNEAKRRLEA Conpu1 EPTGFLFGEKKRVKEEWENIWYYGMFGYKPDTSIQTWALKEAKERMEA Copci EPTGWLFGEKKRVKEDWENIWVIGMFGYKPDTSVQSWALKEAKERMEA Croqu1 ------------------------------------------------ CryneH991 PPSGYLFGERKRVKESWENIYYVGMFGYKPDTSIQSWALKEAKERLEA Crypa2 PPTGWLFGVKKAEKEGWEGLAYYGFGGFKPDTSIQTWALEEARRRLEA Debha1 ------------------------------------------------ Dekbr2 ------------------------------------------------ Dicdi ------------------------------------------------ Dmel ------------------------------------------------ Enthi ------------------------------------------------ Falba ------------------------------------------------ Fomme1 ------------------------------------------------ Fusgr1 PPTGWLWGVKKAEPEGWEWP-TYILLGFKPDTTVSTWALEEARRRLEE Galma1 EPSGWLFGEKKRVKEDWENAWYIGMFGYKPDTSVQSWALQEAKERMEA Ganpr1 EPGGYLFNQKKYEREWWEIPMYFGFGGYKPNSSRQNVVLLHGVKRLVG Gloin1 EPGGYLFGERKRVKEDWENIWIYGMGGYKPDTSIQSWATREAKKRLEE Hisca1 PPTGWLWGVKKYVKEGWEGLWTYGFVGFKPDTSIQTWALEEARRRLER Klula1 ------------------------------------------------ Lacbi2 EPSGWLFGEKKRVKEDWENVWYFGMFGYKPDSSIQTWALKEAKERMEV Lenti61 EPTGYLFSEKKRKKEAWENVWYVGMYGYKPDTSVQSWALKEAKARMEA Malgl1 -------------------MY------FKPDNSVRKWAAPEAEKRLDE Mellp23 QPSGWLFGEKKRVREDWELTWYIGFWGYKPDRSITTWARQEAEKRSEA Mnele ------------------------------------------------ Monbr ------------------------------------------------ Morel2 QPTGYLFGEKKRVKEDWEPMMFYGFFGYKPDTNVHTWAYREAKARMAA Mucci2 EPGGYLFNEKTRVKEDWESIYYWGMGGYKPDTSVVTWAKKEAEKSLKE Mydma PPNGFLFNQKKRKRETWELIWYPGWAIYRPDDNVLDWATKEAEKRIAE Neucr2 PPSGWLFGVREYKREGWEIPFFYGFCGFKPDTSIQTWALEEARRRLEA Orpsp11 ------------------------------------------------ Pench1 PPTGWLFGVKKYVKEGWENIWYYGFIGFKPDTSIQTWALEEARRRLEA Phybl2 EPGGYFFSEKKRVKEEWEDIYYWGMGGYKPDTSVVTWAKKEAEKSLQE Picst3 ------------------------------------------------ Plicr1 EPTGLLFGEKKRQKEDWENLWYYGMFGYKPDTSVQTWALKEAKERMEA Polpo ------------------------------------------------ Pucgr2 QPSGWLFGEKKRVREDWELIWYIGFWGYKPDRSITTWARHEAEQKMEK Punst1 ------------------------------------------------ Rhior3 EPSGYLFNEKVRVKESWENMYYLGMGGYKPDTSLVTWAKKEAEKSLKE Rhoto1 EPSGRLFGEKKRVKEDWENIYYYGFGGYKRDTSIQTWARAEAMKKMEA Rozal11 ------------------------------------------------ Sacce1 ------------------------------------------------ Salro AANGWLFAEKARQKEAWELPFHLFISGQRPNTRTQATYSKIAQEELAA Schco3 EPSGFLFGEKKRQKENWENIWYIGMYGYKPDTSIQTWALAEAKRRMEE Schpo1 ------------------------------------------------ Sorma ------------------------------------------------ Sphar ------------------------------------------------ Spipu1 EPSGYFLGRPKRDWYWWEPLWYFGYYGFSARPTPTEAAKLEAHRRLAE Sporo1 QPTGYLFGEKKRVREDWESIYYWGMFGYKPDTSIEGWARKQAQEKMAN Stehi1 EPSGYLFGEKKRVKEDWENIWYIGMFGYKPDSAVQNWALQEAKQRMEA Tapde11 PPTGKLFNEPKRTKDSWENLWVFGFGGNKPD---DTYLLQSRLKCLR- Thetr TQNGYLFGEKPRKKELWETMMQIGMGGCAPETSIKVWAEEESVARIKR Treme1 PPSGYLFGERKRQRESWELIYYFGLFGYKPDTSIQTWALEEARRRMEE Trire2 PPTGWLWGIKKPEPEGWEWP-MYLFGAFKPDTSVSTWALEEARRRLEA Umbra1 EPGGYLFNEKKRVKEEWETIYYWGMGGYKPDTSVVTWATKEAEKSLKE Ustma22 QPTGLLFGEKKRQKEDWENMYYFGLFGYKPDTSIQSWAMAEAKKRLES Walse1 EPTGHLFAEKKRKWENWEPIYYFGFYAYKPDTNIQTWALNQAKSRMEE Zygro1 ------------------------------------------------ [Cluster3711.fasta_al_trimmed; alignment length = 44] Allma1 TIEKPYIIAGTAIGFFGIGVLAARDPIRRV-FGPPPM-TYP-MP Ashgo11 -------------------------------------------- Aspfu1 SHEKPAIFYSLVVGATGPLMLVTLPPIRRF-FGPIPL-TYP-LP Aurde31 SHENPALFWAVVLGGVGPVFLLVATPISRR-LGPVPT-SYP-VP Batde5 LYHYPTAFVSTILGIAAPVIIFVVYPIRYE-MGHIPK-SFP-VP Botbo1 AHERPVIFWSILLGSIGPVAVGVVPPVRKS-FGRIPT-TYP-VP Botci1 AIEKPAIFFSIVVGSIGPVLVLTVPKIRHR-LGQIPL-TYP-MP Caeel -------------------------------------------- Canalb1 AHVNPALFVSVALGVSAPLVL-LLTPLRRK-YLPVPQ-VYP-LP Cangl -------------------------------------------- Capow -------------------------------------------- Catan2 TVRAPYIMASFAIGGAGIGMALFKDPIRRT-FGPVPL-TYP-MP Cioin -------------------------------------------- CocheC53 AYNKPAYFYSIVIGLAGPIMLVTVPPIRRY-MGRIPL-TYP-VP Coere1 TFEQPFAVWGLALGFAGPALVLIVPPIRDY-MGSIPE-SYP-LP Conco1 ALEYPVYFWSLTIGAFGPPTAYFVPKWRGKLFGAIPT-TYP-LP Conpu1 AHEKPVIFWSLSIGLVGPVAALIVPPVRRGYFGPIPT-SYP-VP Copci AHENPVIFYSCVIGAIGPVLAIGVPPIRRH-FGPLPT-GYP-LP Croqu1 AHENPAIFWSVAIGLAGPVLLAVVPPIRRNYFASLPA-SYP-LP CryneH991 AHEKPVIFWSLLLGLSGPAMVVAVPPLRRS-FGPIPT-TFP-VP Crypa2 -------------------------------------------- Debha1 -------------------------------------------- Dekbr2 AHNKPNIFFPCAIAAMGPVFLFVITPLRKK-FIPLPMGGYP-IP Dicdi -------------------------------------------- Dmel -------------------------------------------- Enthi -------------------------------------------- Falba -------------------------------------------- Fomme1 AHENPVILWSCVFGLAGPVLAVAVPPIRKS-LGEIPT-SYP-LP Fusgr1 ARERPALFWSVIIGAAGPVAMPIVPPIRHY-FGPVPV-TYP-IP Galma1 AHESPVIFYSVVIGAIGPLMALTVPPIRQS-MGMIPA-TYP-VP Ganpr1 LIEQPVITVSYFVGLTGLLLPITVLPLRRY-YGEPPK-SFP-LP Gloin1 -------------------------------------------- Hisca1 AHEKPAIFFSVIIGSLGPVALVALPPIRRY-LGPIPL-TYPRVP Klula1 -------------------------------------------- Lacbi2 AHENPVIFYSCIIGAIGPVMVVAIPPIRER-FGMVPT-TYP-LP Lenti61 AHEQPVIFYSVIIGLIGPTMLVTVPPIRKS-LGPIPT-SYP-VP Malgl1 SHARPVVFYSLLLGALGPVSVVVVPKYRAQ-FGRIPV-SYP-LP Mellp23 AHENPAIFWSIAIGSAGPVLLATVPPIRRNYFGPIPG-SYP-LP Mnele -------------------------------------------- Monbr -------------------------------------------- Morel2 ARDSPYIFTSFVVAAIGPVLVVGVPAVRKS-QGRIPD-TYP-LP Mucci2 AIERPVIFWSFVLGTAGPVMVFTVPKFRREYLGPLPI-SYP-LP Mydma -------------------------------------------- Neucr2 AREKPAYFYSCVIAGLGPVFLTVVPPVRKY-FGPIPV-TYP-IP Orpsp11 -------------------------------------------- Pench1 AHEKPAILASLCIGFMGPVSLATIPPIRRA-LGPVPL-TYP-IP Phybl2 ALERPVIFWSFVIGSAGPLMVWTVPTIRREYFGRLPI-TYP-LP Picst3 -------------------------------------------- Plicr1 AHENPVIFFSVIIGAIGPTLAITVPPIRSH-FGRVPS-TYP-LP Polpo -------------------------------------------- Pucgr2 AHENPAIFWSVALGTAGPVLLATVPPIRRNYFGPIPM-SYP-LP Punst1 AHEYPVLFYSICLGSLGPIMVLTVPPIRRS-LGPIPT-SYP-LP Rhior3 ALERPVIFWSCAIGAVGPVMVWTVPSIRRNYFGPLPI-TYP-LP Rhoto1 AHEQPAIFYSLALGAVGPVLVVAVPPIRKRYFGRIPQ-SYP-LP Rozal11 -------------------------------------------- Sacce1 -------------------------------------------- Salro -------------------------------------------- Schco3 AHEKPALFYALLIGGAGPLLIATVPPLRKA-YGMPPT-SYP-LP Schpo1 -------------------------------------------- Sorma AREKPAYFYSCVIAGLGPVFLTVVPPRAQD-FGPIPV-TYP-IP Sphar -------------------------------------------- Spipu1 -------------------------------------------- Sporo1 ------------IATTGPIAVIAVPEVRRKFFGRPPT-TYP-LP Stehi1 AHEKPVIFYSIVIGLAGPLMVPTVPAIRAK-FGPIPL-AYP-IP Tapde11 AHERPNVFYSLLIGAMGPITLLTVPPIRKS-LGPVPL-SYPFAP Thetr -------------------------------------------- Treme1 AHESPVIFYSLVLGFVGPTMVLTVPPIRKS-FGRIPT-TYP-LP Trire2 ARERPAFFWSVVVGAAGPLLMPIVPPIRHM-LGPIPV-TYP-VP Umbra1 AHEQPVILWSVVIGSIGPLMVWTVPKVRREYFGPLPT-TYP-LP Ustma22 AHEHPVVFFSIVIGSVGPLAVVTVPPIRKA-YGKVPT-SYP-LP Walse1 AHEQPVYLWSFGIGLTGPLLVIAVPEIRSKFFGRLPT-TYP-VP Zygro1 -------------------------------------------- [Cluster3714.fasta_al_trimmed; alignment length = 104] Allma1 SRYQQALVTEAVRSYLEK-VKHEFPVLPYVAPKF-EEYLRFRHPMSRKVTLIVLSAQETHALQLLAGPRY-CPVEKFTMAADRFPAQNKRFLGDTFAELLRQAK Ashgo11 -------------------------------------------------------------------------------------------------------- Aspfu1 TSMAHAEVELHRREYARI-AAWDMPLLPFTLPPE-THILRFRHPAESKVVVELLSEKQRQTFLKLVGTRY-NPDTDVRMSCEKFTAQNKRYLGDIVNTLIKEAK Aurde31 SSVGFQLISIQRIHYMRL-IEGDMFMLPFRPPTE-NNPIIVRHPVTRKRTITVTSDAATHKIRLIAGPRW-TQRPPIKISCEDFPVQNLKFASDTLDKLVEEAN Batde5 TRFEIDFMETADKTSLLK-MKHAKKDLPFEPATP-TKPICVKPPVNNAVALQVLTPPQKHKFLLLAGKAY-DPYMDVSM-ADSKGALSLKQLSGYMDEMIAAAK Botbo1 TSVGHALLRQRRLTYLRL-IESEVPKLPFTPPPTGSSPLIVRHPAAQKGCLVVSSPAAIHKFKLLAATRW-SARTPFKITCENFPSQNLKWCSDVLDRMIAEAN Botci1 TTLAHMELEQVRRHYNRL-AAWEMPMLPFVPPSA-ETPLRFRHPAEKKVVMEFLTEVQTDKLRKLVGPRL-NPETDVKMSCEMYPAQNKRYLGDMVDSLLAEAK Caeel -------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------- Catan2 SAYQMQLVTTAVRSYLEK-AHNELPHLPYSPPSK-RAYLRFRNPMDRKVTLYVLSKDQEHALKLLAGPRF-DPIDKITMANDRFMAQNKAWLADTFAELLKQAK Cioin -------------------------------------------------------------------------------------------------------- CocheC53 TSHGHGELQQHRREYARL-IAWELPLLPFTPPTS-ATPFRFRHPAANKVVVEFLTAPQISKLIKLAGPRY-NPSTNIKLSCEKFDPQNKRFLGETISSLIAEAK Coere1 HTYGHLLLESIRRKYERM-IEFELPTLPFKPPSS-ECILHFELAQDRKVILRVLKTPELHKFLLLVGVRY-NPQADLKMSEDREALLNKRRLADTLASLIAQAK Conco1 TSMAHHYLRQVRRKYMRQ-IKYEMPTFAFVPPTS-KQYLNFQHALDNKAVMIVFTPEEVHFIKLICEKTY-YPDTNIRIGQTKYPEENKLWLAKTWKELVKVVK Conpu1 PAGGHIDLRQKRLHYLQL-IDHDVPRLPYAPPTA-SVPLAVRHPMTPKRTVVVKGDAALHTAKLLAGARW-TPEPPIKISCEDFPAMNLKWISDTLDRLVAEAN Copci PVLGHKMLQAQRLHYMRL-IEHEMPKLPFIPPSSQETPLVVRHPAASKRSITVKDAKAIHKFKLIAGPRW-TPNPPFKISCDTFSEMNAKWASDALDRLIKEAN Croqu1 -------------------------------------------------------------------------------------------------------- CryneH991 TSLGWMRMFRIQEGLVRK-IEEDREALTKFTPP--TAPIRLTSRYHTKCVLLVSTSEAVHRFKLLAGPRW-TPGKPIKISEERFERQNRRSASDILERLVSAAN Crypa2 TDIAHAKLEEHRRAYARI-AIWEMPLLPFEPPTM-NEPLRFRHPAEKKVVVEFLTDIQQEKMKKLAGPRY-NPEKQIKMSCESFEAQNKRYLAETVEKLVADAK Debha1 -------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------- Dicdi -------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------- Fomme1 ---------------MRI-IEHDMPNLPFVPPSS-DRPLVVRHPATAKRTVVVKGPNAQHAFKLLAGPRW-SPLPPIKISCEDFPGMNLKWISDVLDRLIDEAN Fusgr1 TSMAHGKLDEVRRKYARL-AVWELPLLPFEPPTD-QEVLRWRHPAEKKVVVQFLTPVQTDKLKKLSGSRY-NPETEIKMSSDSFEAQNKRYLSNLIDDLITAAK Galma1 PSAGHILLQQHRLHYMRL-IEHEMPKLPFVPPSS-STPLVVRHPAALKRVIVAKGKDAIHKFILLAGPRW-SPVPPIKISCEDFPSMNLKWASDTLDKLIEEAN Ganpr1 DRYQLDFLETAEKDVLLK-MKNDAPTLPFVPE-P-SRIFTYHPDRSVTVSFRVLSKEQHHKLLLLVAGSY-DVDTDATITCDTFAGQNKKWLSDTVDRLIEEAK Gloin1 TKPGFDIFLAQQRNYLRK-TKYELPQLEFIPPSP-TSILCFKSPIQNKVVLTILTQKQLHKFVLLCGPRF-NGI--FKFSCDKFPNQNKKYLSDLVDKLLEEAK Hisca1 TTMAYDELEQHRREYARI-AAWEMPLLSFTLPKD-THLLRFRHPAEAKVVVEFLTEEQRIQ------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------- Lacbi2 PSSGHLMLREQRLHYLRL-IEHEMPKLPFTPPTS-ATPLIVRHLASIKRVVVVRTPQAIHKFKLLAGPRW-TPNPPIKISCEDLPEMNLKWASDTLDKLVAEAN Lenti61 PEPMHKALQQQRLYYLRL-IEHEMPKLPFVPPDS-SNPLIIRHPAAAKRTIVVKNADAIHKFKVLAGVRW-TPDPPFKISCEDFPAMNLKWASDTLDRLLAAAN Malgl1 STIGHLRLQKERLKYYRV-MANEFPKLPFIPPSP-SSFLTMKHPDTRKVVLTFSTPLSKHKFLLLAGPRWQPPNASVKIASNSMPSQNMKWCSDVLDRMVSEAN Mellp23 -------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------- Morel2 STIGYDRMEAQRRKYLRI-TKYELPKLPFQAPTN-TQILRFRHPAGPKVVMTVLTNAELHKFLLLVGSRY-NPVNNIKMSCEKFQSQNFKWLSDTLDKLINEAK Mucci2 TTIGHNLFDNIRRKYLRK-TEFELPKLPFEAPTK-DQILKFKHPVEKKAVLSVLNETEKHKFLLLSGPRY-NVNTELVMSSEKFPKQNKKFLIDTLQKLIKEAK Mydma -------------------------------------------------------------------------------------------------------- Neucr2 MSLGHGKLEEHRREYARI-AVWEMPLLPFVPPTS-EEVLRFRHPADRKVVVEFLSEVQQRKLMKLAGPRY-NPEKDIKMSCEKFEAQNKRYLGDLIEKMIAAAK Orpsp11 -------------------------------------------------------------------------------------------------------- Pench1 TSMAHAEMELHRREYARI-TAWDMPMLPFTLPPQ-THILRFRHPAEPKVVVELLTDAQRQTFLKLAGTRY-NPQTDIRMSSEKFGAQNKRYLADVVNSMIKEAK Phybl2 TTIGHDLFENIRRKYLRM-TNYELPKLPFVPPTS-GQILKFKHPVERKAVLNVLTEQQRHTLLLLSGPRY-HVDTDLIFSSEKFPKQNKKYLSDILDKLIEETK Picst3 -------------------------------------------------------------------------------------------------------- Plicr1 TATGHMIWRHQRLYYMRL-IEHEMPKLPFVAPTA-STPLVVRHPASAKRTIVVRDKDAIHKLKLLAGVRW-TPDPPVHISCEHFSAQNIKWASDALDRLISHAN Polpo -------------------------------------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------------------------------------- Punst1 SSIGHEILEQQRLHYMRL-IEHEMPQLPFVPPSN-RAPIVVRHPGKAKRVLVVRNEHAIHKAKLIAGVRW-SPEPPIKIACEDFPEMNLKWASDVLDRLVEEAN Rhior3 TTLGHNLFDNIRRQYLRK-TEFELPKLLFEAPSS-DQILKFKHPVERKVVLSVLNDTEKHKFLLLSGPRY-NVDTQLVMSSERFPQQNKKFLIDNLNKLIKEAK Rhoto1 TTPTIMKMEKQRLHYLRL-EQHQFKDLKFVPPSK-EQFIAVRHPCSRRISIRVSSPEALHKFKLLAGARWHPPLPPFEMSCDVFPRMNEKWCSDTLEKLLNEAN Rozal11 -------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------- Salro DRTGHVHVENSGQDLSRINIRHHAQHLAWREPLP-EEFLQIEIPEARKVILTALNAAEREKLLQLVGSRY-RAATDLKLVGRRYPEMNLQYVKDLITVLVAEAK Schco3 TTLGHHMIDELRLYYMRL-IEHECPKLPFVPPSP-DRPLIVRHPVTNKRAMTVHSERAKHKVKLLAGTRW-TPSPPIKISCEDFPAMNLKWIRDTLVRLCKEAN Schpo1 NNLSWQKIQEHERELYRK-AAYELPGLSFKKPAD-SQIFRFEEKMNPKVVVTFLEEKQRHVLRLLVGPRY-NPEEDVRISSDKYSLQNKYHLIKILTSLIEESK Sorma MSLGHGKLEEHRREYARI-AVWEMPLLPFVPPTS-EEVLRFRHPADRKVVVEFLTEVQQRKLMKLAGPRY-NPEKDIKMSCEKFEAQNKRYLGDLIEKMIVAAK Sphar AEMLYADMDKLK-------SHAHITRFPWKLPAI-ENVVRISHKVERKVVLEVLTEVGIATMAALTGPRY-NKDKKLKLTSVRFDEENKAYLLALLEKIVRASQ Spipu1 HRYELDFVETAKKDLLLK-MKNDVEMLPFTPP-P-TSHIVTTPPYSTKVTVQVLTPAQRHKFLLLAGDKY-DPYSDVTVSAETSEEMNRIGLVKLLNGMVNEAK Sporo1 -------------------------------------------------------------------------------------------------------- Stehi1 TSAGHLMIMRQRLTYMRL-IDHEMPKLPFVPPTS-EAPVSVRHPAANKRVLTVNDDKAVHKLKLLAGPRW-SPSPPVKIACEEFPNMNLKWASDTLDRLVAEAN Tapde11 -------------------------------------------------------------------------------------------------------- Thetr -------------------------------------------------------------------------------------------------------- Treme1 TSLGWLRLFKIRQELFRK-MEVDREALPFIPPP--KGAIRLTSSRHMRQVLMVKGSEATHRLKLIAGPRW-TPHRPIKISEDRFENMNRKSTLDMLEKLVDAAN Trire2 TSMAHGKLDEIRRHYDRL-AVWEMPLLPFVPPTE-KQVLRWRHPAEKKVVVQFLSEVQTEKLKKLAGPRY-NPETEIKMSCESFEAQNKQYLINLVNDLIAAAK Umbra1 TTIGHELFGNIRRSYLRK-AKYEIPKLPFVPPTS-SQILRFKHPVESKCVLNVLNDQERHKLLVLSGPRY-NPETGLTLSSEKFPKQNKKYLSDLLDKLVAEAK Ustma22 PSLGHQILQRKRLKVMRT-VEFEIPKLAYTPPKP-EQCLQFRHPASRKVVLTVKDTPSKHKLLLLAGSRF-HPKSNIKISCELFPRQNMKWCSDTLDALVKEAN Walse1 -------IESKRLAYMRM-EEFELPKLEFKPPAK-DEVVKVRHPASVKSVVTVADASSKHKLKLLAGPRWSGPESRIKISSEQFPAQNMRWCSDKLQLLLKESN Zygro1 -------------------------------------------------------------------------------------------------------- [Cluster3716.fasta_al_trimmed; alignment length = 112] Allma1 TVLGLLVSEVGLP--DTFQTWFSVTQVHVWMAMVRLRAQGLVNHMFRDMEDRLWSIVDRSLKDCLSMFYGGILAYDEA-LSDALLASALWRNLFQFVRVVREELAHLEQVPA Ashgo11 ---------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------- Aurde31 -----FYGECDMP--RTFQTWFRIANLHAWLLVVRFRAQALVTSFFEDVEERMRRVITKYMKIYREQWNGLHFALDIA-LADAELAAAVWRNFLALSRYIRRETVRLQGISD Batde5 NPVGYFVKSLGLD--ESFQGWFSMTILHVWILNARLRGQEVFNHIWLDVEIKLHTRISQITSGLLDSYYGQTLAYDEG-IGDSILAAALWRNFFGLIEYTRRQLVHVEQTSL Botbo1 KLFGYFHQECRLP--PTYQTWFQLTNLHIWLLTVRLRAQELLNHFFLDAEDRMRRVIRGYMKEMRDQWAGSGASYDLG-LGDQEMAGALWRNIFAFVAHLRREAKRLEQISD Botci1 ---------------------------------------------------------------------------------------------------------------- Caeel KSDGL--EAFGLG--DYMSSWYKLTLMHTWMVLMRLHSRGLLSTMWLDIDNRLGMTGQNDMKHMHGLHLQTFFEYDEG-FDDRVLAGAIWRCLYMVVTYMRSTVAWLETQDT Canalb1 ---------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------- Catan2 PLFGLLVREAGLP--DTFQTWFSATQVHVWMVMVRLRAKGVVSHMFRDMEDRLWAIVDKSLKEFLSIFYGGILSYDEA-LSDALLASALWRNLFQYVRLVRRELQLLEAVER Cioin ---------------------------------------------------------------------------------------------------------------- CocheC53 ---------------------------------------------------------------------------------------------------------------- Coere1 RILSRWVEECRLP--ETFQTWFSTTSFYVWMAMVRVRAQGIVDSFFQDAEQKIRRIVNDTLKDLVSSFKGTVMSLDEG-FSDAALAAAIWRNLLPIVSYTRAQLQILDSYDI Conco1 MSLKLYTETLNMP--DNFQTWVSVTQLHIWLTIVRLRMQYLVNVFFHLLEEKIRRIIKNSIKDFIVGFRGSTIAFDEG-MDDAVLAAALWRNMLSLVRYVRMQLKYVESIPS Conpu1 RALGYWLEKCALP--PTFQTWFTITNLHVWLLTVRLRAQGLIDHFFQDTEERVRRIIVRQMKILKEQWNGMGFALDLG-LGDAELAAVVWRNMLGLVTYIRREVSRLEKIDD Copci RVLGYWQQGCYLP--PTFQSWFTITNLHIWMLTVRLRAQALIDHFFLDIEDRIRRIVTRQMKIFKEQWAGMGLSLDLA-MGDMEMAAAVWRNLLGLTRYIRRELKRLESVPD Croqu1 KLLGYWVSECGLP--DSFQSWFQVTQLHMWLLTVRLRAQELVNHAFIDTEHRIRTLVKGYMRTMLHQHYGAQTGLDWALVSDAFLAAAVWRNIFGVVVFIRSELVRLNKISD CryneH991 KLLGYWYEECDLP--KTFHTFFSIHLVYLLITLIRLRAQTLLTHFFNIVENEIRSAVQTRMKDYANWWREAQLGMDYA-IADAELASWVWRLIFGIVRFIRREMARLDKISD Crypa2 ---------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------- Dicdi ALLGFFYKQSNLP--VNVRSWFTISVLHIWIVFVRLRKIDLYDRFWEDLEKKIARFIPKYLKDFYTTYLGTLISYDEG-LDDTVLCNALWRNFYAMVKFIRVQLNHIDNLPD Dmel NKVGFFFRDFNLP--NTFNSWFLVTELHVWLLLMRSMANCIVEAMWGDVNTRAKSRTRQQIETLSEQFQAALIAYDEG-IDDRVLACALWRRFFELVKYVRQQASMLDSLPR Enthi ---------------------------------------------------------------------------------------------------------------- Falba TLVGLFVERAGMT--DSFQTWFLVSYLHVWMCSMRLRVKQLVELFIEEVELRIH--LDATMKVFVAQMLGVDIALNEG-ICDSLLASTMWRNFTGLVRYVRSHVAHLDALSQ Fomme1 GNLGMWHKECRLP--PTFQTWFTVTNLHVWLLTVRFRAQGLVDHFFLDVEERIRRLVTRQMKILREQWAGLNASLDYA-LGDAEMAAAVWRNFLGLTKYIRRELKRLEGISD Fusgr1 ---------------------------------------------------------------------------------------------------------------- Galma1 NLLGYWINDCFLP--PTFQSWFTVTNLHIWMLTVRLRAQALVDHFFIDIEDRIRRIVTQQMKIFKEQWTGMGLSFDVG-LGDMEMAGAVWRNLLGVVGYVRRELARLERVSD Ganpr1 RRLEYFINTLKLP--DTFETWFYLTTLHMWMLSTRGRARDMSEILWTDCEKRMYTLINRGLKDLLAAHYGHLLAYDEG-LGDAILAGALWRNLFSAIKYVRHELVKLDRASS Gloin1 KAFGYYIGACGLP--DSFQTWFSVTLLHIWMLMVRFRVQQLVNHLFEDAEWRMRSIIRHYIKDLLNQFHGGVMAYDEG-MDDPVLAAALWRNILVLVKHVRHELQRLDHLSY Hisca1 ---------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------- Lacbi2 NVLGYWQQACHLP--PTFQSWFTITNFHVWLLTVRFRAQGLIDHFFLDVEDRIRRLVSQQMKIFKEQWAGMGLSFDLG-LGDMELAAAVWRNLLGLVAYMRRELVRLESLSD Lenti61 RLLGYWKQDCHLP--PTFQSWFTITNLHVWLLTVRLRAQGLIDHFFLDVEDRVRRLVTRQMKIFKEQWAGMGMSFDLG-LSDAELAGAVWRNLLGVVEYVRRELIRLESIPD Malgl1 RLLGYWYKECALP--ASFQTWFQLTNLHVFLLLSRIRAQELINHFFIDTESRMRRLVKGYMKDLHLQHRGSTVAYEEG-LDDIRLSAAIWRNVWGVTRWLRREVYRLGHLPD Mellp23 NRLGYWINECGLP--DSFQTWFQITQLHMWILIVRFRSQEFVNHGFLDTEHRIRSLIKSYMKTMLDQHYGFLVGFDWA-LSDSVLVEAVWRNLFGILVWIRIELIRVSRISD Mnele ---------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------- Morel2 -----WIDTCGLP--DNFQTWFSITHLHVWLLMVRIRAQQLVNHFFHDIEDRMRRIISTYMHDFLAQFHGGVLAYDEG-MDDPIMAAALWRNLFTLVDYVRKELHNLDTMSS Mucci2 KAMGYYIKECNLP--DNFQSWFSVTQLHVWMLMVHLRAQELVNRFFEDAEARIRKVINSYIKDLLAQFHGGVVAYDEG-MDDPVLAAALWRNLFA----------------- Mydma KLRNSFFKVCGLP--DTMQSWFYIMELHVWMVLVRLKPYKMVEIMWEDIEQRIRTDLKESMEEFNQQFHGLIIAFDEA-LHDTVLASALWRNMFVLVEYIRKQIHHLESLDS Neucr2 ---------------------------------------------------------------------------------------------------------------- Orpsp11 ---------------------------------------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------- Phybl2 KVMGYFVTSCNLP--DNFQTWFSVTQLHVWMLMVRLRAQELVNRFFDDAEDKIRRVIKSYIKDLLAQFHGGVVAYDEG-MDDPVLAAALWRNLFAMVKYIRRELKALEEIDG Picst3 ---------------------------------------------------------------------------------------------------------------- Plicr1 NLLGYWRNDCDLP--PTFQSWFMITNLHVWLLTVRLRAQALIDHFFLDVEDRIRRLVTQQMKIFREQWAGLGISCDLG-LGDAEFAGAMWRNFLGLVEYCRRELVRLEKISD Polpo KLMGLLYKSVGLP--LTVRSWFAMTLLHMWMVFVRLRKTDIYDRFWEDLEKRIVKFAAKYLKEFYTNYLGSVVAYDEG-LDDVIMADALWRNLLAMVKYIRVQLNKLDNSPN Pucgr2 RLLGYWVDECGLP--DSFQTWFQVTQLHMWLITVRFRSQEFINHSFLDTEDRIRTLIKNYMKILLHQHRGFQTVLDWA-ISDQFLAGVIWRNLFGLVIFIRKELVRLDQVTD Punst1 RLLGYWRRECDLP--PTFQSWFTITNLHVWLLTTRLRAQGLIDHFFLDVEDRIRSLVSRQMKILREQWAGLGMAFDVA-LGDAEMAGAVWRNLLGIVAYIRREVHRLEQLSD Rhior3 RLMGYYIKECNLP--DNFQSWFSVTQLHVWMLMVHLRAQELVNRFFEDAEDRIR--VNKYI--------------------------ILYMNMYG---YIDIVI-------- Rhoto1 KLFGYFYEECYLP--PSFQTWFSITTLHVWLLSVRFRSQELINQMFVDVENRIRRLVKGYMKDLLEQYHGACAAYDEG-LGDPVLAAAIWRNVFGFVVFIRKEVHRLERLPD Rozal11 ---------------------------------------------------------------------------------------------------------------- Sacce1 ---------------------------------------------------------------------------------------------------------------- Salro VLGGFFIRTCQLP--DTFQSWFLITHLHVWMCLVRLKQKALVELFWKDVEYRMRRIIQESTRELFSMFYGLLFAYDEG-LKDVVLAEAVWRNLFHMVKYIRREVQRLDDTDS Schco3 SILGFWKEDCYLP--STFQSWFTIVNLHVWMLTVRLRAQALLDTFFYDLEDRITRLITRQLKTHRDQYMGFTLSMDAA-LGDMEMAASVWRNLLGLVTYIRREIKRLEDIPD Schpo1 IYQKYWYQKCEIP--MTFQSWFQITQLHLWILHTRIRGQALTTRFFEDMELRIHRISGMYLKDLFQQQTGAIFGYDQG-MSDAVLATSVWRNLFVIVKFIRLNVYRLSCLST Sorma ---------------------------------------------------------------------------------------------------------------- Sphar ---------------------------------------------------------------------------------------------------------------- Spipu1 NPIGYFVQALNLP--DNFQTWFAMTLLHVWIYNARLRAQEIFDHIWLDVEIKIHRQLSKIMSNLVSAYYGQTLAYDEG-LGDAILAGALWRNLLGLVTYVRKQLQHIDQADR Sporo1 ---------------------------------------------------------------------------------------------------------------- Stehi1 SVFGYWRDECHLP--PTFQSWFTITNLHIWILTTRLRAQGLIDHFFLDVEDRIRALVTKQMKIFREQWAGLGLAFDLA-LGDEELAAAVWRNLLGVVEYVRREVRRLGQMSD Tapde11 KVLGRWYNVSGLP--PTFQTWFQITQLHLWMIMVRMRAQQMTNHFFNDAEARLRRIIQTYMKDLLLQWRGSVAAYDQA-LGDAVMAAALWRNMYGMVGHVRANLKLLDGTSD Thetr RMLGW--ARVGLPADDSFRAWYGLVVLQTWMYMVRMRTQALFDSLWEEVEVRIRSLLARNVKDLLGMFYGAAVGYDEG-FDDTVLAAALWRNLYSMVDYVRAQIAHLQTLPP Treme1 KLFGYFYDECKLP--PTFQTFFQIHLLYLLILLPRLRALELLNHFFEMAESEMRRVV--------------RLAVDYI-LADLELAGWVWRNLFQVVKFIRREMVRLDKISD Trire2 ---------------------------------------------------------------------------------------------------------------- Umbra1 RMLGYYHQDCNLP--DNFQTWFSITQVHVWMLMVRLRAQELVNRFFEDAEDRIRRIVESYVKDLLAQFHGGVVAYDEG-MDDPVLAAALWRNVFTIVQYIRRELKILDDYDS Ustma22 KLMGYWYGDCALP--ETYQTWFQITNLHVYLLLARFRAQELINHFFIDAESRMRRLVKGYMRDMHMQQRGSVLGYDEG-LGDATLAQAVWRNIWGIVTFIRAESLRLANLSD Walse1 KLFGYFLKEAHLP--PTFNTWFHLTNLHIWMLTVRFRAQELINHFFIDIESRIRRTIKSYMMAYLEMWRGSGVAYDEG-LGDAVLAAAFWRNIYSLVEYTRSELHRLESLDD Zygro1 ---------------------------------------------------------------------------------------------------------------- [Cluster3717.fasta_al_trimmed; alignment length = 52] Allma1 VLGLLFAVIGVSLVSPDRNLIVTSLVLTLSCIYLMWAVPYMAQLHPLVPPKR Ashgo11 VVATFLSVVLASAV-ENQTVWRSTIILSMSMMFLMWAVTYLSQLHPLVVPRR Aspfu1 ---------------------------------------------------- Aurde31 VFAFFIISAGLMALGPHQVLLRSSFLLTIVCCYLMWAITYLAQLHPLIVPKR Batde5 ---------------------------------------------------- Botbo1 VLYVFVAVVLLSALSEHQTLIRTSVSLTLVSCYLMWAITYLAQLHPLIEPRR Botci1 IVIGLIIVVLACAAGENQTIWRSSLILSFASCYIMWAITFLAQWHPLIVPRR Caeel ---------------------------------------------------- Canalb1 VVAVFIVVVALSCL-ENTTVFRSSVILALSMCYLMWAITYLAQLHPLEAPRR Cangl ---------------------------------------------------- Capow ---------------------------------------------------- Catan2 VFILFCLLIAACLAGHDRNLHVSSIILTLTCVYLMWAITYMAQLNPIIPPKK Cioin ---------------------------------------------------- CocheC53 PIIGLIVVVIFCAAGENQTVWRSTLVLSAAAMYIMWAITFLAQLHPLISPVR Coere1 VFWVGLLICGVCVGRSDPTLWRTCTILSLTCCYLMWAITYLAQLHPIIVPKR Conco1 ---------------------------------------------------- Conpu1 VILLLAVVAGLMVCGPQQTLYRTSLMLALGSCYLMWMITYLAQLHPLIAPQM Copci VFLMLAVTLGLMAAGPNQVLIRTSLMLTFAVCYLTWAITYMAQLNPIIAPIV Croqu1 ILGILIIALAAAGLGDNQVVVRTSIVATIVCCYLMWAIVYLAQLHPLIQPVR CryneH991 VVFVAFVIAAIGAAGKNQTLLRTSLLLTLACCYLMWAITYLCQLHPLITPRR Crypa2 IFIGLFIVAAMCVGGENQVLWRSSVILAFVCCYLMWAITFLAQLHPLIEPKR Debha1 VIIAFIITAALSTL-ENTTVWRSSVILGLSMCYLMWAITFLSQLHPLEAPRR Dekbr2 VIIVLIANLVAGSL-QDRTVWRSTVSLMLAMMYLMWAFTYLCQLHPLIEPRR Dicdi ---------------------------------------------------- Dmel ---------------------------------------------------- Enthi ---------------------------------------------------- Falba VVWMFFVFAALTGLPNNRGVGYAMAVATGMCLYLMWAICYLAQANPLIAPQR Fomme1 VFAVLVIVLGLMAVGPQQTLIRTAVLLTLSCCYLMWMVTYLVQLHPLISPKR Fusgr1 ---------------------------------------------------- Galma1 VLFMFVITIALMTAGPQQVTIRTAFMLTFAACYLMWMVTYMAQLHPLISPIH Ganpr1 VLIATILMVALSVVPPNDGVTKTSLTLVFVCCYLMYAFTYLAQYNPLVAPER Gloin1 IVWVGCAIAGLVAIGPNQTTIRTSIILTLICIYLMWAITYLSQLHPLIVPKK Hisca1 ---------------------------------------------------- Klula1 ---------------------------------------------------- Lacbi2 VFLLLVITAGLMTAGPNQVVIRTALMVGLAAFYLLWMITYMAQLHPLIAPVR Lenti61 TLFILAIAVALGFVGPNQTLIRTSVLLTLACCYLMWTVTYLAQVHPLESPKR Malgl1 TIWVLFAAILTGAVGPNQLLIRTSVIMVLACCYMMWACAYLAQLHPLIQPKR Mellp23 IFGILIIAALLAGLGDNQVVVRSSILASIICCYLMWAIVYLAQLNPLIQPKR Mnele ---------------------------------------------------- Monbr ---------------------------------------------------- Morel2 ---------------------------------------------------- Mucci2 IVWAFFGVAIVCALGNDQTVIRTVIIMSLICCYLMWAVTYLAQLHPLIFPKK Mydma ---------------------------------------------------- Neucr2 IIIGLVIVAGMCVAGENQVLWRSSLILAFVSCYLMWAITFLAQLHPLIEPRR Orpsp11 VLIVLAVVVVLSLLGPNQAVIRTSIILTLSCCYLMWAVTYMCQLNPLIQPER Pench1 LVIGLVIIVALSTAGDNQTLFRSTLILTFVSCYLMWAIVFLSQWHPLIAPKR Phybl2 ILWALLGVVLVSAIGNNQTVIRTIIIMSLVCCYLMWAITYLAQLHPLINPIR Picst3 VIIVLIFVVALATL-ENRTVFRSSVILALAMCYLMWAITYLAQLHPLEAPRR Plicr1 VLFLLVIAVGLMACGPHQIVIRTSIMLTLAACYLMWMITYLAQVHPLEAPRK Polpo ---------------------------------------------------- Pucgr2 IFIVLILAVGLSFLGDDQIVIRTAVIATITCCYLMWAIVYLAQLHPLIQPKR Punst1 VWFLLVIVLGLMFVGPNQTLIRTSFSLALACCYLMWMVTYLAQVHPLICTRW Rhior3 IIWVFFAVAAVSALGNNQTVIRTVIIMSLACCYLMWAITYLAQLHPLINPIK Rhoto1 IFLTLLIAAGAAAGGENQVVIRTSITLAITCCWLMWAITYLAQLHPLIKPIR Rozal11 ---------------------------------------------------- Sacce1 VVGVFIVVSAMSVL-NNQAVWRSTVILTLAMMFLMWAITFLCQLHPLVAPRR Salro ---------------------------------------------------- Schco3 VVFWLVIVVVLMACGPQQVVVRTSIMLALASCYLMWMITYMAQLHPLICA-- Schpo1 VLLVGLLTALMSVVGNNTSTWQMSLILTFSCCYLLWAITYLAQLHPLEAPSR Sorma ---------------------------------------------------- Sphar ---------------------------------------------------- Spipu1 VIVTFILFAIAGGVSPDQVLYRTVLSLTLACTWTMWALTYLAQLNPLIVPER Sporo1 ---------------------------------------------------- Stehi1 VLLVLVIALGLMAVGPQQVLVRTSVMLTLACLYLMWAIAYLAQLHPLMVPRK Tapde11 ILVVFAILVGLSGAGDNQTVWRMTSILTLVSMYLMWMLTYVAQLHPLVAPRI Thetr ---------------------------------------------------- Treme1 IVSVGFVVAIIAAAGKDQVLIRSSVALALTCCYLMWAITYLAQLHPLIAPRR Trire2 IVIGLLVIVALSAAGENQVLWRSSLILAIVSCYLMWLITFLAQLHPLIAPRR Umbra1 ---------------------------------------------------- Ustma22 TVWVFLIAAGASSAGPNQVLIRTSVVLALTCMYLMWFIIYMAQLHPIVKPKR Walse1 ---------------------------------------------------- Zygro1 ---------------------------------------------------- [Cluster3723.fasta_al_trimmed; alignment length = 86] Allma1 -------------------------------------------------------------------------------------- Ashgo11 ITVRVIKSFPYRNVKSFVLHGYDLERKTAKDL-RAFRTVYDALKIYTHAHGS-KTVNLVINLNR--DGV-RDETELSLFNEYAADP Aspfu1 -------------------------------------------------------------------------------------- Aurde31 LTVRVIKSFTYRTERSVVLHHVDLTTATVGEL-KPYRTVLDTIKLYTKAHGN-KTMNLIINLDH-DDGL-ENEAELSFFNEFKQNP Batde5 LTIRLIKSFEYRTFKNLVLQHIDPE-MLVKDL-KPYHNTFDCLKLYVKAHGS-KTQHLIINLDH-DESV-ENETELSFFNLYKAHP Botbo1 ITVRIIKSFEYRTERSLVLHDVNLEQVTVGRL-KPYRTAFDTLKLYTKAHGA-KTTNLIINLDH-DEGL-ENESEVSFFNQFKRNP Botci1 -------------------------------------------------------------------------------------- Caeel -------------------------------------------------------------------------------------- Canalb1 ITVRIIKSFPYRNVKNYIIKDIDLKSTTPKQL-RPYRNVYNSIKIYTKAHGS-KSMNLVINFDN-DEDI-RNETELSLFNAYKENP Cangl ITVRVIKSFPYRNVKNLVFHDYDLQNKTAGDL-RPFRNVLDTLKVYTHAHGS-KTVNLVINFDH-DEGV-ENETEISLFNAYKANP Capow ITVRCIRSFEHRALKSLVLHGVDLAHTSGGDL-APFRAIYDTIKIHSQAFGA-KTNNPIINLDH-DDGV-KHETELSMYRTYKAHP Catan2 -------------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------------------------- Coere1 ITIRIIKNFEYRLYKNIVIP-VNTTSTTVGAL-KPYRGIYDTLKLYTQAFGN-KTQNLVINTDD---GI-RKETEISFFNAYIMNP Conco1 -------------------------------------------------------------------------------------- Conpu1 ITVRVIKSFEYRTHRSLVLHHLNLESTTAADL-KPYRNVLDTFKLYTHAHGS-KTTNLIVNLDH-DEGF-ENETEVSFFNKFKLNP Copci ITVRIIKSFKFRTQKSLVLHNIDLTTTTVGQL-KPYRNVLDTLKVYTKAHGS-KTSNLIINLDN-DDDF-ENETEVSFFNEFKKNP Croqu1 LTVRIIKSFKFRTCKNLVLPHLNLETMTVEEL-KPYQNVLDTFKLYTKAHGA-KTTNLIINLDH-DDGL-EHESEVSLFNDFKLNP CryneH991 LTVRVIKSFEFRTQKSVILKNLDLRTLTVEAL-KPYRNLLDTMKLYTVAHGH-KTQNLIINLDH-DDGA-QNETELSFFNKFKLDP Crypa2 -------------------------------------------------------------------------------------- Debha1 LTIRIVKSFPYRNVKNHILPSVNLKETTPLDL-RPYRNVYDTLKIYTKAHGS-KSMQLVINLDH-DDEV-ENETEISMFNEFKQNP Dekbr2 LTVRIIKSFPYRNVRNQIFHHVDLENTTPKQF-RPFRNVYDTIKIYTHAHGH-KTMNLVINMDHDDDPI-ENETELSIYNAYKKKP Dicdi LIIRVIRSFEYRTIKNLILKDIDLN-TNVSDF-TPFKTKYDSMKIFFVPHGQ-KPNNLTINIEN-D-GV-VYETEISFFVKYKENP Dmel -------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------- Falba LTIRVIRSITFRNSRNLILRNINLKTTTGRDL-RPFRTIFDTLKIYHTAHMS-KKGDLIINTGS-EHGV-RNESEISLYNEYLADP Fomme1 LTLRIIKSFEYRTEKSLVLHDVNLETTTVDGL-KAYRTLLDTIKLYTKAHGA-KTTNLIINLDH-DEGF-ENETEASFFNAFKLNP Fusgr1 -------------------------------------------------------------------------------------- Galma1 ITVRVIKSLRYRTERSLVLHNLDLNTTTVAQL-KPYRTVLDTLKLYTRAHGA-KTSNLIINLDH-DEGF-ENETEVSFFNEFKVNP Ganpr1 --VRVIKSLEFRTVKSLVLRDVDLTDTTVGKL-KPYLNGQDTLKIYVSAQGT-KSSNLVLNVGQ-DDGV-GHETEISFFNAYKTHP Gloin1 ITIRIIKNFEYRTIKNLVLQHINLETTTFKEL-KPFRNVYDTLKLYTKAHGA-KTQSLIINMED-DEGI-ENETEISFFNTYKTHP Hisca1 -------------------------------------------------------------------------------------- Klula1 ITVRVIKSFPYRNVKNIIFTDYDLKNKTAKDL-RPFRNVYDAMKIYTHAHGS-KTVNLVINFDH-DDGV-KNETEISVFNSFKANP Lacbi2 LTVRIIKSFKFRTERSLVLHNVDLTTTTTAQL-KPYRNVLDTLKLYTNAHGA-KTSNLIINLDH-DDGF-ENETEISFFNDFKLNP Lenti61 LTIRVIKSFEYRTEKSLVLHHVNLEETTVGQL-KPYRNTLDTLKLYTKAHGA-KTTNLIINLDH-NEGL-ENESEVSFFNEFKQHP Malgl1 -------------MKPLVLRDIDLTKCTTPQL-KAYRNVLDTIKLYTQAHGA-KTTNLIINLDH-PEGV-QNETELSLFHAFLQHP Mellp23 LTIRIIKSFKFRNFKSLVLHHLNLNELTLDGL-KAFQNLLDTFKLYTKAHGS-KTTNLIINLDQ-DEGL-ENETELSLFNEFKSNP Mnele VTIRLIRNFEYRTIRTVPIRDVD-TQQTVDQFPPPFKTHYDTLKISHQAGSF-KANDIVINLEG-DEGV-VSETEMSFFNKYKLNP Monbr -------------------------------------------------------------------------------------- Morel2 LTIRVIKSFEYRTSKNLVLHNIDLTATNVGQL-KPYQTVFDTLKLYTKAHGA-KTMNLIINMDH-DDGI-ENETEISIFNAFKQHP Mucci2 LTVRCIKNFEYRTCKNLVLQHVNLETSTVGDL-KPYLNVFDTLKVYTVAHGH-KTMNLIINVED-DDGL-ENETELSFFNEFKTHP Mydma VTVRLIRSFEHRNIRNIVYHQVD-TSMTCKSFPPPFRKFYNKMKIEHQPFGM-KSNDPVINRDN-DEGV-INETVLSFFRKYSSNP Neucr2 -------------------------------------------------------------------------------------- Orpsp11 -------------------------------------------------------------------------------------- Pench1 -------------------------------------------------------------------------------------- Phybl2 ITVRCIKSFEYRTCKNAVLKHIDLENTTVGEL-KPYLSVFDTLKLYTVAHGH-KTQNLIINMED-DKGI-ENEAELSFFNAFKKNP Picst3 ITVRIIKSFLYRNVKNHIVHSINLKETTASQL-RPYRNIYDSLKIYTKAHGS-KSMNLVINFEN-DQGV-ENETEISLFNAFKANP Plicr1 LTLRIIKSFEYRTERSLVLHSVNLETTSVGEL-KPYRNVLDTLKLYTKAHGA-KTTNLIINLDH-DEGF-ENETEVSFFNKFKLHP Polpo LTIRVVKSLEYRNIKNLLVHGSDLN-MKVSEF-LPFRTLLNTMKIFFIPHKQ-KPNNLTINLEN-DEGV-A---------KYKSNP Pucgr2 ITIRIIKSFEYRNSKNLVLHHLNLETIKTDQL-KMFQNVLDTFKLYSKAHGA-KTTNLIINLDH-DEGL-ENESEVSLFNAFKANP Punst1 -------------------------------------------------------------------------------------- Rhior3 ITVRCIKNFEYRTCKNLVLQHVNLETSTVGDL--------NTLKVYTVAHGH-KTMNLIINIED-DDGI-ENETELSFFHQFKDHP Rhoto1 LTVRIIKSFTYRTTKNLLLPHIDATTMTVGQL-KPYRTVLDTLKLYTKAHGH-KTMDLIINHET-DDGI-ENETEVSFFNEYKRNP Rozal11 -------------------------------------------------------------------------------------- Sacce1 ITIRVIKSFPYRNVKNIVLHDYDLADKTAKDL-RPFRNVFDTLKIYTHAHGS-KTVNLVINFDH-DDGI-ENETEISLFNRFKENP Salro -------------------------------------------------------------------------------------- Schco3 LTVRVIKSFEYRTEKSLVLHNVNLETTTVGRL-KPYRNVYDTLKLYTKAHGS-KTSNLIINLDH-DEGF-ENETEVSFFNEYKKHP Schpo1 LTVRVIRNFEYRTLKNVVFHDIDLATTTVDQF-KIYRTTFDTLKIYVKAQQH-KTQNLAINLDH-DDGI-ENETELSYFEAYQANP Sorma -------------------------------------------------------------------------------------- Sphar -------------------------------------------------------------------------------------- Spipu1 -------------------------------------------------------------------------------------- Sporo1 VTVRIIKSFEYRTTKNLLLPHIDATTMTVGQL-KPFRTCLDTLKHYTKAHGS-KTTNLIMNLEN-DEGI-ENEAEVSFFNAFKLNP Stehi1 -------------------------------------------------------------------------------------- Tapde11 LTIRVIKSFPYRIVKNLVLQHVDLTSTTTSQL-KVYKGILDTLKLYTRAHGS-KTTNLIINLDH-EDGI-ENESELSFFKAFKNDP Thetr -------------------------------------------------------------------------------------- Treme1 LTIRVIKSFEFRTQKSLVLKGLNLELETVGNL-KPYRNVFDTLKLYTQAHGHKKTTNLIINLDH-DDGA-ENETELSFFNKFKLHP Trire2 -------------------------------------------------------------------------------------- Umbra1 LTVRCIKSFEYRTCKNLVL-HVNLEVMTVGEL-KPYLNVFDTLKLYTVAHGH-KTQNLIINMDD-DDGF-ENETEVSFFNEYKKNP Ustma22 ITIRIIKSFEFRSMKAYVIKSIDLTTTTVSEL-RAFRSYLDTLKLYTRAHGS-KTTNLIINLDH-PEGI-ENETELSFFNQFLANP Walse1 LTIRLIKSFEFRTTKNLILKGIDLTNTTVEDL-KPFRTVLNCIKLYTQAHGH-KTTNLIINVDN-HHEIDENETELSLFNQFIQNP Zygro1 ITVRVIKSFPYRNVKNIIFQNYDLRSKSPQDL-RPFRNVFDSFKIYTHAHGY-KTINLVINFDH-DDGI-ENETEISLFKNYKANP [Cluster3742.fasta_al_trimmed; alignment length = 124] Allma1 ILETILHDTSLVLLDFHLERLFSSARVRVIVG-VKGDLAITPVYLTCKTTHRVIYADAQDVLLTA-AGRIAESCFTNVALFCWITPR------------------------------------- Ashgo11 ILSTIRYDPHLFLLKEHQQRLNLAMKMRVLIS-RSGNMRIESPFTTFKTTRRQHYNDAREVLVYN-DFQLMEGSITSVAVKKYVTPFLASGCLCGVMRHFLLQKGLVQEIDVRHLVLLFNAVMG Aspfu1 IISSLRYEPALYLLPYHQERLRKAARLRIVID-RDGTCTVESPFTTHKTTSRDVYTAAREVLIVN-PGEIMEGSITTPYFRRWITPPLSSGGNAGTTRRYALSQGFCSEITIAELCWLSNGVRG Aurde31 -----------------------------------------SAFTRNKTTRRDHYNVAREVILYN-EGEVTEGSVTNVSFWRWVTPNTSSGGLPGTVRRWLLGQGRIMEVRRDDIVMLTNSWHI Batde5 ---------------------------------------------------------------------------------------------------------------------------- Botbo1 LITSLRYDPLLLPLVLHRDRLLQAARLRILLS-ESGELLGSSMFTSYKTTSREHYTAAREVLLWN-EGEITEGSIRNVAFWRWVTPSAEGGCLAGVMRRWLIESERVREVLREEVVLLSNGVEG Botci1 ---------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------- Canalb1 ILSTIRYDPNLFLLPEHTSRLQFSMKVRGLFK-LDGSVTFESPFTSFKTTKREVYNEAREVVLFN-TNNVMEGSITNIAVKRWVTPLLSSGCLCGVTRHFLLRKNFIEEVTLEQLVLLMNAIMG Cangl LLSTMKYDPSLLLLGEQFVRLKLAAKMRVLLK-GDNSLEFQSILTSLKTTSRDHYASAREVLIWN-DEEIMEGSITNIAIL-LVTPPLSSGCLCGTMRYYLMRKKLIKAIEKNFLILIFNDVMG Capow VSTFTRLVPSDALAVAHATRLAQSLRVKFSVT-SSSTLAIDNPALAHKTIQRGIYDRAKDVLLVN-DQHVTEAAIANIAIREWITPPLCAGILPGTLRAELVRAGLLHEITVQMLIFCMNSLRG Catan2 ILETLLWVPASFLWSLHLDRLSKALRIRLLVD-LNGRATVQSDFLIHKTTHRTICDSAQDVLLHT-RGFITESCIANIAVLSWTTPKIDVSLLPGCMRSVLLDDNVIHEVPLTWVVVGFNSVRG Cioin ---------------------------------------------------------------------------------------------------------------------------- CocheC53 LFTSLRYDPLLYMLAYHRDRMVEAAKLRLLFD-KAANLTVESPFTLLKTTKREMYDQSREVMLYN-ENELTEGTLTSLYLFRWVTPPVGAGGQRGTSRRWALGSGYCMEVSIETVVWVSNGVRG Coere1 ILETTAYALDTFLLAEHLERMQISARIRMLLD-NAGHLSVQSIFVRCKTTFRKIYDSAVQVLLYN-TGMITEGNIANVAVSLLFTPPLSAGLLAGTMRQQLLNSGQIREISIDQFVLCMNSVRG Conco1 ---------------------------------------------------------------------------------------------------------------------------- Conpu1 ---------------------------------------------------------------------------------------------------------------------------- Copci LLTTTRHDPALFLLPYHHERLVEAARVRILLS-HTGSLQVTSIFTSTKTTNRKVYDDARDVLLYN-SQMIMETSIFNVAFFRWVTPAAATGCLLGVARRWLLEHNRITELTIGSIVLLFNGLQG Croqu1 LLTTIKYD--HPLLKYHLNRLKKTHRIRLTIG-PNHHIQIVNPFLLYKTTNRTIYDNIRDVLMYN-ENQITETTISNIGLRTFITPKSSCGLLPGIQRDILLKDGVIIEITLHQLMICFNALRG CryneH991 ---------------------------------------------------------------------------------------------------------------------------- Crypa2 LFTSMRFDWNLYMLDYHRDRMLKAARLKILLS-EDGQLALESELTHFKTTKREMYDQAREVLIVNKESLIMEGSLTTPYFWRWVTPPVSYGGQDGTTRRWALKAGIAELVKVSDLVWLSNGVRG Debha1 ILSTIRYDPKLFLLDEHYHRLVFTLKVRLLVS-MDGDVKIESPFTSFKTTNRKVYSAAREVLLIN-GEQLMEGSITNVAIRRWITPQLSSGCLCGVMRHFLLRKDFIEEITLRSLILLFNGIMG Dekbr2 LLTTMRYDPSLYLIDNHVRRINLGIKVRVLVD-KTGEVKLDNPFTSFKTTNRTAYETAKDVILYN-TGNVTESTFCNVAFQRWVTPPLVSGCIEGTMRKNLMDSQLLYEIPIKSIILLFNAVRG Dicdi ---------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------- Fomme1 LFTSFRYDPKLLFFNYHIERLVAAAGLRVLLS-ITGDIRVESAFTSFKTTARAHYDAAREVLLYN-EGEIMEGSVRNVAFWRWVTPPDRSGGLPGTVRRYLLERGMMKEIRVSDVVLLSNGWDG Fusgr1 LFTSMRYDPRLYMLDFHRDRLLRAAKIKLVVS-RQGDIKVESEYTHFKTTKREIYDTAREVLVIDQDGSIMEGTFTTPYFWRWITPPVASGGQDGTSRRWALERGLAFEINVKTLCWVSNGVRG Galma1 LLTSTRYDPFLFLLPLHFDRLVSASRLRITVS-PEGRIAVTSVFTQTKTTFRDIYDLAKDVVLYN-EGQITETTIFNVAFRRWITPSTTSGCLSGVMRKWLLDNGRICELTKDSVVLLFNGVQG Ganpr1 ---------------------------------------------------------------------------------------------------------------------------- Gloin1 --------------------------VRLTVN-KQGIPTITDIFLYHKTTHRNIYNDARDVLLYN-ENEITECSIANIAVEYWKTPKIECGLLGGVMRSHLIENGEIIPITLSEIIKCFNSVRK Hisca1 ITSTLRYDPDLYLLSYHYDRLLAAARIRVLLN-AVGVITVESLFTRHKTTVRDQYTASREVLLYN-PGEVMEGSITTVYFRRWVTPPLSSGGNAGTSRRYALTAQMCVEVRVEELVWLSNGVRG Klula1 ILATIRYDPHFFLLGEHYKRLKLALKMRVLVN-KDGTMKIESPFTTFKTTKRDHYNKAREVLVYN-DYQLMEGSITNVAVKSYTTPYLSSGCLCGVTRYFLLRKGLLQEIDVRDLILLFNGIIG Lacbi2 LLTTTRYDPYLLLLPYHRDRLSVAAHVRITLS-RSGKLAVTSLFTITKTTNRRIYDEARDVLLYN-PQLITETTIFNVAFYRWITPALSSGCLPGVMRRWLLEKGRIRELTRSVVILLFNGAQG Lenti61 LLSTVRRDVQLLLLAYHRDRLTEAARIRILLS-HTGALSVTSIFTRTKTTRREHYTAAREVLLYN-EGIITETSIRNIAFVRWVTPSASTGCLTGVIRRWLLEQGRVVELTRTDIVLTFNGVEG Malgl1 ---------------------------------------------------------------------------------------------------------------------------- Mellp23 LLTTMLYDP-NPLLERHLNRLRNAHRLRVTVG-PDNQVTIITPFLLFKTTQRDLYDSVRDVLMYN-SGQLTESTIANVAVKRWITPATSCGLLPGVKREELLEKGEIQEIMISELVICFNALRG Mnele ---------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------- Morel2 LLETILYDPKEFLLDYHCDRMIASARLRVLLD-FDGAITIQNMFLKHKTTEREVYNEARDVIMYN-EGEVMEATIANVAIEVWITPPLSSGLLNGTMRRKLLETGELKEITVSELIKCFNSVRK Mucci2 LLETILYIPGIYLLEQHLNRLEAAIRVRLLVG-TDSKITVEDPFILHKTTRRDMYNLSRDVVLWN-RKEITETSITNIAIRFWKTPKIECGALPGVFRTFLLEKGEMVEITVQDL-KVFIT--- Mydma ---------------------------------------------------------------------------------------------------------------------------- Neucr2 LFTTLRYDPLLYMLPYHRDRILRAARIRVTVS-EKGELGITSAYTHFKTTKRQIYDEAREVLIVS-EGEVMEGSIATPYFWRWVTPPVGSGGNAGTTRRWALERGIAVEVRANSLCWLSNGGRG Orpsp11 ---------------------------------------------------------------------------------------------------------------------------- Pench1 LISSLRFDPGLYLLAYHQDRLIAAARLRVVVN-SQGKARVESGFTTHKTTARDDYMAAREVLVVN-PGEVMEGSITTPYFLRWITPPLSSGGNAGTTRRYALSQGFCLEISRDELCWLSNGVRG Phybl2 LLETILYDPQQYLLNLHIARLLLAIRVRLLLS-KGGVLSTSNPFVTHKTTCRDVYEDARDVVLWN-KGQVTETSIANLAIGTWKTPHHSSGLLQGVFRQKLLEENDVEEITKEDL----VSAHE Picst3 ILSTIRYDPSLFLFEEHVQRTQFTLKVRCLFH-LNSDLVVESPFTSFKTTTRSHYSDSREVILFN-PNNLMEGSITNVAVKRWITPQLSSGCLCGVMRHFLLRKNYLEEISMDQIVLLFNAIMG Plicr1 LLSSTKYDPFLFLLPYHFHRLALAAKVRITLS-RKGALHATSLFTRTKTTWRVSYDEARDVILYN-TSQITECSTSNVAFYRWITPPLSTGCLAGALRRWLLAQGRIKEIRKDEVVLLFNGVGG Polpo ---------------------------------------------------------------------------------------------------------------------------- Pucgr2 ---------------------------------------------------------------------------------------------------------------------------- Punst1 ---------------------------------------------------------------------------------------------------------------------------- Rhior3 ------------------------MRVRLLVD-VDSNVHIENPFVIHKTTRRGMYDKSRDVVLWN-EGEITETSIANIAIRV--------GRLFASIHYFIRRDKR------------------ Rhoto1 LMTALTYSPSRSLLNRHLARLRDAHRIRLSIL-PTGQPHAEEPFLRYKTSQREVYDEARDVLLFN-SRQLTETTISNVAFRLYITPSTECGLLEGVMRAELLEKGEIKEVTIDDLIICFNGVRG Rozal11 ---------------------------------------------------------------------------------------------------------------------------- Sacce1 VLATFRYDPGFFLLDEQYQRIRIALKMRVLVS-KTGDIRIESAFTSFKTTSRDHYARAREILFSN-KGLLMEGSITNVAVIQYVTPRLATGCLCGTMRHYLLRLGLIEEIDIGSLVLLFNGVMG Salro ---------------------------------------------------------------------------------------------------------------------------- Schco3 -------------------------KLRITLS-SSGVLSVTSIFTKTKTTQRSVYDAAREVLLYN-EGEMTEASISNVAFFRWVTPPSSTGCLPGVLRAWLLEQGRIREIKKDDVVMLTNGVHG Schpo1 LFETTLYDGELFLLPSHLQRMKASARVRWELS-KAGDVTVQNPSCINKMTNRAIYIEAMDVLLYN-HGFVTEATIFNVAFHRWITPSLKHGLLSGTMRKNLLENGSIHELQKDNLVLLFNSFRK Sorma LFTTLRYDPLLYMLPYHRDRILCAARIRVTVS-EKGELGITSAYTHFKTTKRQVYDEAREVLLVS-EGEVMEGSIATPYFWRWVTPPV-SGGNEGTTRRWALERGIAVEVLAGSLCWLSNGGRG Sphar ILETLLYTPESYCLLHR--RIHPNT-VRLLFD-GKS---VEDVFLRFKTTHRTTYNEARDVVLYN-EGEITETSICNLAVE--VTPPVSCGLLAGVQRSELLVAGTITEVLLSDLILCFNSARG Spipu1 ---------------------------------------------------------------------------------------------------------------------------- Sporo1 ---------------------------------------------------------------------------------------------------------------------------- Stehi1 LITATRHDLVLMLLRLHHSRFLDAVKVRPSFS-RSGTLSISSVFTRTKTSLRTPYTSARDVLLWS-EGMTTETTVRNVAFFRWVTPAEGTGCLTGVMRRWLIDSGKVVVLWKEKIVLVFNAVEG Tapde11 ---------------------------------------------------------------------------------------------------------------------------- Thetr ---------------------------------------------------------------------------------------------------------------------------- Treme1 ---------------------------------------------------------------------------------------------------------------------------- Trire2 LFTSLRYDPALYMLDYHRDRMLRAARFKILVS-REGVVSFESEYTHFKTTKRDMYNSSREVLLVNHDGSIMEGSLTTPYFWRWVTPPVASGGQDGTSRRWALERGLAVEIPANSLCWISNGVRG Umbra1 LLETILFEPGKYLLDYHLDRLLTSARVRLLVN-SDGEVELQSPYVLNKTTQRDLYNAARDVLLFN-QGEITETSIANIAIE-WITPRVKCGLLPGVFRRHLLESGQVQEIHIDDLIRCFNSVRK Ustma22 ---------------------------------------------------------------------------------------------------------------------------- Walse1 LLTTLRYTPKGYLYDMHVQRLIDGIRVSVQLDLVDLSINAASQLLRYKTTDRDIYNDSKDVLMHN-NGFMTETTIANIFYKFWYTTPASDGLLPGLMRQSLLDSGYCKELRLSELLKASNALRG Zygro1 ILSTLRYDPSFLLLGEHFKRLNLSLKMRVLIY-DSGKMRVESPFTTFKTTYRQPYSAAREILVYN-DFQLMEGSISSVAVIRFITPPLASGCLCGTMRRYLLKKGLIDEIDVRDLVILLNGVMG [Cluster3744.fasta_al_trimmed; alignment length = 66] Allma1 RGGNRGGRDRFSWEDVKNDKRENYLGHSVMAPVGRWQKGRDLTWYRVEELRRIKAAEQDAMMVALG Ashgo11 ------------------------------------------------------------------ Aspfu1 KEGSRGGRGEFKWSDVKDSARENYLGHSLMAPVGRWQQGRDLQWYDREELQRVKQAEEEAMARALG Aurde31 RGGTRGGAAEFKWTDVSADKRENYLGHSINAPTGRWQKNKDIHWYRLEEIRRIKEAEADILAIQLG Batde5 REGNRGGQGLFKWDDVKDDKRENYLA---------------LDWYQQSELAEIKRLEEEALTEALG Botbo1 RGGTRGGQAEFKWTDVSADKREHYLGHSINAPTGRWQKNKDVHWYRREEIRKVKEAEEDALAVALG Botci1 KSGSRGGV-NFSWDEVQSSQRENYLGHSLMAPVGRWQKGKDLNWYRKEEIRKIKEAEEDAIARALG Caeel ------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------ Cangl ------------------------------------------------------------------ Capow RGGCRGGKDQFKWDDIKNAKKEAYLGNSLMAPSGRWAKNRDFNWYAREEIARIKAQEAEALASVLG Catan2 RGGNRGGRDQFSWDEVKNDKRENYLGHSVMAPVGRWQNGRDLTWYAQDELARVRAAEEEAMMVAL- Cioin ------------------------------------------------------------------ CocheC53 KEGSRGGRGDFKWEDVKNDARENYLGHSVMAPVGRWQQGRDLSWY-KEEKRKLKEAEEDAMLAAMG Coere1 ------------------------------------------------------------------ Conco1 ------------------------------------------------------------------ Conpu1 RGGTRGGQAEFKWSDVTVDKRENYLGHSINAPAGRWQKNKDIHWYRKEEIRKVKEAEAEALSAALG Copci RGGTRGGQAEFKWSDVSADKRENYLGHSINAPTGRWQKNKDIHWYRQAEIQKVKQLEAEAIAAAL- Croqu1 RGGTRGGQGDFKWTDVADDKRENYLGHSILAPVGRWQKNRDITWYKQEEIKAIKAIEEEALSVALG CryneH991 RG-------------------ENYLGHSINAPVGRWSKHKDIHWYRAEEVQRIKQQEEDALAAALG Crypa2 KSGSRGGV-NFSWDEVATSARENYLGHSLKAPVGRWQQGKDLQWYRREEIQKIKEAEEDAIAKALG Debha1 ------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------ Dicdi ------------------------------------------------------------------ Dmel ------------------------------------------------------------------ Enthi ------------------------------------------------------------------ Falba ------------------------------------------------------------------ Fomme1 RGGTRGGQGEFKWSDVSADKREHYLGHSINAPTGRWQKNKDVHWYKLAEIKRIKEAEADAMAQMLG Fusgr1 KSGSRGGV-NFSWDEVANSSRENYLGHSLKAPVGRWQKGRDLGWYRKEELRKIKEAEEDAIAAALG Galma1 RGGTRGGQAEFKWSDVSADKRENYLGHSVNAPTGRWQKNKDIHWYRAEEIRKVKELEADALSVALG Ganpr1 RGGTRGGQDQFKWEDVKDDKRENYLGHSLLAPVGRWQRNRDLTWYEADELRKFKEAEAEALAEALG Gloin1 --------------DVKTDKRENYLGHSLHAPVGRWQQGKDLTWYRMEEIRAIKEAEADVMAELFK Hisca1 KEGSRGGRDSFKWSDVKTSTRENYLGHSLMAPVGRWQQNRDLSWYREEEIKRIKEAEQEAMARALG Klula1 ------------------------------------------------------------------ Lacbi2 RGGTRGGQAEFKWTDVSADKRENYLGHSINAPTGRWQKNKDVHWYRVEEVRKIKELEADALAVALG Lenti61 RGGTRGGQAEFKWSDVAQDKRENYLGHSINAPTGRWQKNKDIHWYRREEIRQIKEAEAEALAAALG Malgl1 ------------------------------------------------------------------ Mellp23 RGGTRGGQGDFKWTDVADDKRENYLGHSILAPVGRWQKNRDITWYKEEEIKAIKLAEEDALSLALG Mnele ------------------------------------------------------------------ Monbr REGNRGGQGLFKWDDIKTERYEQYLGHSVMAPIGRWQQNRDLTWFRRIERELVKQQEQDLLAEALG Morel2 RGGTRGGQDQFKWEDVKEDKRENYLGNSLLAPVGRWQKGRDLTWYKQAEIQSIKDAEAEAMAEALG Mucci2 ------------------------------------------------------------------ Mydma RGGVRGGQDQFKWEDVKNDKKEYYIGHSLMVPTGQWTKGKDIFWYRAEEIRKVKELEARAMAAVLG Neucr2 KSGSRGGV-NFSWDDVASSARENYLGHSLKAPVGRWAKGRDLNWYRREEIRRIKEAEEDAINRALG Orpsp11 RGGSRGGQDSFSWENVKNDKRENYLGHSINAPVGRWQKNKDLLWYIKDELEEIKQKEAEAMAEFLG Pench1 KEGSRGGRNEFKWSDVQTSVRENYLGHSVMAPVGRWQQNRDLNWYEREELQRVKEAEEEAMAIALG Phybl2 ------------------------------------------------------------------ Picst3 ------------------------------------------------------------------ Plicr1 RGGTRGGQAEFKWSDVSADKRENYLGHSINAPTGRWQKNKDVHWYRAEEIRKVKEAEADALAVALG Polpo ------------------------------------------------------------------ Pucgr2 RGGTRGGQGDFKWSDVADDKRENYLGHSILAPVGRWQKNKDITWYKREEIQRIKAAEEDALSAALG Punst1 RGGTRGGQGEFKWSDVSADKREHYLGHSVNAPTGRWQKNKDVHWYRLEEIRKVKEAEAEAMAVALG Rhior3 ------------------------------------------------------------------ Rhoto1 RGGTRGGQGDFKWSDVAADKREYYLGHSLNAPVGRWQKGKDLTWYRREELKRIKEAEEDALAQALG Rozal11 ------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------ Salro ------------------------------------------------------------------ Schco3 RGGTRGGQAEFKWSDVSADKREHYLGHSINAPTGRWQKNKDIHWYRQAEIRRIKEAEAEALAIALG Schpo1 GAGTRGGQAQFQWEEVRNDKKGRYLGQSIYAASGRWAEGKDLEWWYKKEILEIKEREQRMLAEALG Sorma KSGSRGGV-NFSWDDVASSARENYLGHSLKAPVGRWAKGRDLNWYRREEIRRIKEAEEDAINRALG Sphar RGGTRGGQAEFKWSDVKDDKRENYLGHSLNAPVGRWQNKRDLQWFRRQEMTLIKQQEQEAMSLML- Spipu1 RAGTRGGQGLFKWEDVKEDKRENYLGHSLNAPVGRWQKNKDLLWYITSELEEIRKNEAEALAEALG Sporo1 ------------------------------------------------------------------ Stehi1 RGGTRGGQAEFKWSDVSADKRENYLGHSINAPTGRWQKNKDVHWYREEEIRAIKEKEAEALSLALG Tapde11 RLTVRGGRDQFDWNNVKDDKYQNYLGHSLKAPVGRWQHNKDLEWFRLEELRVLKQAEEEALAAAMG Thetr ------------------------------------------------------------------ Treme1 ------------------------------------------------------------------ Trire2 KTGSRGGV-NFSWDEVANSSRENYLGHSLKAPVGRWAKGRDLNWYHKEELRRIKEAEEDAMARALG Umbra1 RGGVRGGQDQFTWESVKDDKRENYLGHSLMAPVGRWQQGKDLTWYAAEELRRIKEAEADALAVALG Ustma22 RGGARGGAAEFSWDKVKQSKREFYLGNSVAAPTGRWQDGRDINWYRREELRRIKEAETAELYAKLG Walse1 RGGTRGGAGNFSWNAVKEDKREYYLGHSVKAAAGRWQKNKDIHWYKKAEIQKIKEAEEDALSLALG Zygro1 ------------------------------------------------------------------ [Cluster3745.fasta_al_trimmed; alignment length = 186] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 KLNNVLQDVVGA-AEAVAEEPILDQLDTVMRELIDASVEMKLHQNVLEGLRQRILQGDINDQWEKNYIKKTRQKYAKDDRYQRFRENVWNVQDGKAMPPLSSDDSDDGGVTQDFKDPLTMTLMVDPVESRICKHTFSKASIMEYLCPATGCNKQISKADIELTRHVNAYKRRQQRRDDDEDDDDDI Batde5 ---------------------------------------------------------DMLEWFEQNYQEKLTTRYTSNEKYDAFRQAVWDVRPNVPF-----VNSEDTTQTVSYKCPITLRIMTNPVTSRVCKHSFSDAIFQTFTCPIPGCDKRIRAADLALKRKVVAWLRAKRHEASEEDDCDQI Botbo1 KLKGMTGEITEA-AAMIEEAQMVDQLDTAFRELIDTKMELSAQNAAIEDIQRAITQRDAMDRYERKYQAKTKQKYGKNEEYVKFRQTIWEVRADEAMPPATQEGSDDGGVKKSYTCPLTLTPLQKPMTSIKCNHSFSAHAIREYLCPATGCAHKLTMRDLELENKIKLMNRRKKRMEEEEDDEDEV Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow QLKLVSQMCSEV-AVDLATR----ALEEGQLSLLACEERLAHLIKVLDDVQKECRGGPLDSYVEE-YDPAK-------ERFTRYRKEVWKANGSRPNPD---EDDTDPEI-----CPITKSRLVEPVRSSRCTHTFSRKAIQQLYCPVPGCNQEIRLEELDMEKQLRRTDIQQRTQRASDSDDEEV Catan2 KLRSLAQFMAEL-GT-YSEDDVVAAVDAALALVADSLKTSLLQEAALRE--EQENRMQSQSDSESDKKGKIRAHFAESAVAARAK--MWELT-----PRFAPDEDDDTAEKEDFRDPITAGTFKHPVRSSLCKHRYENHAIRQLICPVAGCPHYVREDQLIFERKLKRHLAELEKAKTQGDEYMEL Cioin HLDGAMHNVIEV-GIELLENSGMDKLQECIGGLIRAEQRVKAFTHSVDSLK------ELEDSM--ELE--AFKR---ETEKVTNDPSLWDHE--SFIEQMKTPRGDDMAGEATTTCPITQCQMADPVKDKICGHSFEKQAILAHICPSTGCTNIIDRNNLALKQLIQRRVKDSNQPQSS------- CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 -LQSRLHG---A-ALDLEESEKVSEIDASLRTLIDAQHQLEVERTLVTRLATQLDSEEYMTAWKQ-YEKTSASKYGKNNMYREFRQQIWDVKEGEPMPNLFDDDSDEEGARVNYRCPVTATWLVDPVTSKICKHSFSREAILDYICPVDGCSNRIKPQDLVLERNVSRHLRQLESEETAQ------ Conco1 HIDI----LTKA-SVEL--RDDLNVIEDQVKTILDNKEKLNYFNLHLRDYQTLARS---DGNF-------Y-------TDYIEYKTKVWKVHPNQPLPQLGRSRNNDEEIRESLKCPITTNYYEDPVVSSQCKHSFSRKAIEECICPVSGCDKIIRQSYLDLKKKVEEHLTEQQTQA------EEQ Conpu1 -------------------MESLTQVDEIMRNLLNIDHEMKSHEETLKEMYQKIIVENAMERYDNDFNSKTRQKYASSNDYVKFKQGVFETQPDMAIPPINASDDDDGGVTQDYKCPISLTLLVNPMASRVCNHSFSAVAIREYLCPATGCNAQISMNDVDLEKKVRLVARRAQREQDD-DA--EV Copci --------IQDI-ASALADREPIESLDSVMRELIDLSTEMISHKEVIDDIRQKLVQGNALDRYMSEYQKKTRQKYAKSDAYIEFRSSIWNAQPGQPMPPLTTTFDDDGGQTQDFKCPITLTILIDPLTSRLCGHSYDAAAIRSMLCPAAGCKKMIAISDCDLAKKAKNHKRRLERQEEEHSDVDEV Croqu1 KLNTMIQDLSEV-AASLEEEEQIAEVDKHVRDVIETMRILEFRQEALTELREFLYHHKLDTELSKEWNKLSRKKFGGDRLYRDFRTGIWNAKKGAGVPSIKSESSDEGGSTQITKCPLCIKWLTKPVRSNLCNHPLCQKCFQDYLCPYTGCSQRISEAIVDLEQQVKRAKRQ-QDQEAEADSDDE- CryneH991 --------IKDA-AFAIEE-ESLKNVEGSLFKAFDQRQVLQIKIRCLEQLEARLKGGNLNDAFNHEYFAKSRAKLRKFKEYIEFCSNLWSIN-DDACPPVSNEESDDGGQTQTYRCPITLTLYQDPMTCTKCSHTYSKIAIYDLICPVTGCSVTIEKTDLSMQKRANEFARRQQDKDDEEDDIASI Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi DVDKILSNIKQA-ALSLANKDIMDNIDKSFLTTIALEDAVITYSRNAANLKSHVERANSQDRIGLDYKKPLLERSKTSVKYNNLKREVHSVNPLDGL-----NDEDEASQTISIICPLSQATLVEPVRAEQCLHVFSKAIIFQMFCPIAGCGRQIAKTQLDVEETVKKELRRKENQQRRDDDITEV Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi QTEVI---ITEY----IES-TQTEEVKETLKSMLELES---KLNGHLAALRRSQDNPEYKQAVINDH-----------PKIKEMKRRIWYARSE-PY-----EDENEISNTRSFICPLTKKPFVNPVKAQVCGHIFSKQAIYNLICPVAGCDHSFGINDLAMDREKKNAMSEDSSSEAE------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 --------VESV-AVAMAEEEALKELETLMRELLDLQAELLAHEDTLNTLSNSIARGNIQQRYTDSWQNRTRQKYARDEDYIRFKSSIFEVQPDQGMPPLTDESDDDGGVSQVYTCPLSLRVLENPMSSKICKHSFSKDSIVEYYCPAAGCSELQGLSDFDLERKVKAHVRREQRRQAEDSEEEQV Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 KLKGIAEDYKDV-AGAMAESKDLRELDRAMKEFLDIDAEMTAHAGSLDALYQQIARNDAATRYEDEYLGKTRQKYARNPKYIDFHSNIWDVHPTEPMPPLTDDDDDDGGATQNYDCPITLTLLVNPVTSKVCKHSFSADAIKEHCCPAAGCNKSFRASDCALAKKVKVYARRMA-AAAEDSDAEEV Ganpr1 QIAAGRPGCIEL-AVELEESEQVAEIELSLKTLIDMENELLLQREVIQ---EMARDLDLATEFDTEFDRTHADKYTRHDSYRSFKTSVWEVHP----P----PADDNEAVHRKPICPITRQPFKQPMTAKECGHSFEKSAILDLFCPQSGCPKILKKVNLDLRRQARLYIESQREQRE-EEDSMDV Gloin1 ------------------------------------------------------------------------------------------------MP--SLQNDDDGHQKDSLTCPITTLPLENPVTSDLCKHSFSKEAILSLMCPIPGCEKQIMEHNLRLERKVALENKKKKKSNKMDIEYTNI Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 KLKGISNDIGDV-GVSLAEEESLKEADKIMKDLLNISAEMKAHSQAIIDIHQLVAQGNAGQRYKDEYAGKTRQKYAKSAEYYSFKSAIWDVQPEKAMPPLTESDDDDGGVTQTLKCPISLRTLEDPLTSSVCGHSFSAGAIRDYCCPASGCNKAFRFADCDLAKKVKAFNRRAERAAEEESDAEEV Lenti61 KVHGLSGDIREV-GAAVAEEKALATVDSLMRDLLDTEQELSSHEQALDDLYNRISKGGITDAYEKAYNARTRQKYAKSDHYQQFKQAIYEVHPDTAMPPVVDDDDDDGGVTQDYKCPLTLTILVDPLTSKECGHSYSAAAIRAYLCPATGCRKQICLNDLVLARRAKEAARRERAREEDDDDG-EV Malgl1 ----------------------------MTRDLIDLVTESETRIAVLEELETLIQSGSLDCVYKEAYRAQTRKRYSKHPAYIEFKSRIWEVE-EGAMPPLVDNEDDDGGTVRQFRCPITADILRDPVIHAPCQHAYSREALASYMCPAAGCQHVLMRSAISLKRRVARYERQLLRREELQQEATAV Mellp23 KLKTLINELIDL-GCGLVEDQEILQVNQEVLDLIETIKVLEIRKDVLSDLRETIYHFDLNREFKKDWNSLSRKKFATHPSFKEFRKAIWTART-SDVPPVKSDSDDEGGGTQTYKCPLCIKFLTNPYRSKLCRHAFCQTCFDQHFCPQSGCHQSLTRNDVRFMAEIKRAKRRIERQEAEVDDEDE- Mnele QLRLLDSS---------EMDLDLSEMEQLYKNFQGVQYRLEAQKEGIERSKSQALQENLGNHYKAENEPQHG---VSLPAPRQAVSSEEELA----------QLQDEAGAKISLTCPISQTRMVHPMLNTQCGHTYDRNAVNEHICPVAGCVGHVNQANLQI---AEL-----------LQDSSN- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 SLRPAIATVTEA-TLEYEEAKAVQAAEDALLSIKEFQLQMEAEKQALERLTSIIAAGVASKLEESRRKQEAATVGMNPD-LQDFRAKVWEVHNTSAVP-TSSDEDDEGNNLQSLKCPLTTQFLEDPVTSAVCKHSFSSAAIHALICPVHGCNRPIALENLALARKVARQIMIQDEMPQHEEEYTTV Mucci2 K-PSLANDLTLA-AQSHEEKAMVDELDEAFKDFVNLEYKMNLQRKSFETLKQRIATGDPIAYYENTFNAESDDATRINQKYLSFKQHLWNINPDEEMPSLRANDDDDGPTKISLKCPITMLWLDEPVT------------------------------------RVARAKEREAAAKEKAEDTTEF Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 -----------------------------------------------------LNRNSVNKEYSARYQCQPYKRYAANKDFQEFRKTLWDVKQGRTMPSLLDEEGDDTNRQESMICPLTKKIMTDPLISRRCEHSYS-SVIKDYICPVAGCVHFVTMGDLLLARKIRRKKFIEMEEEMEREKYE-- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 TLAQVLNDLIDA-AIDLEEGDQVKRLQKSVPDFIDLEHKYSSQKETIQKIKQKSLQSDMIKDYEDEYNSLSKQKYGENEFMSEFKQAVWNVKPNEEMPENEEGGDDDSSTKRSLTCPLTTTWFEDPVTSYDCKHTFSKKPIVNMICPNPGCNKTWKMGCFLMERRVGR-AKMIVEEAKNE------ Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 RLIGLAQDVKDV-GASMAEVKALSELDLIMKDLIDVEAEMLAHEKTIEDLHQVIAQEDSVDRYEKAYRNKTRQKYAKSEEYAQFKQRIWEVEPDKGMPPINDSDDDDGGATQDFKCPLSLTMLVEPYTSTLCEHSFSKKAIIDYICPTSGCKKVLTLGVVDLEKRVKAVVRRQQRQAEDGDE--DV Polpo DIESIDKTITQS-ALSLESSLILTTIDQDFLKCLYEEQFIAKHKQDIATLKQYIERTHAQ-----NQHQPTLEALKQNKEFKEYKQKIWNINPFD-------DGGNEASQTISIICPITKKNFENPVKSRTCGHTFSKEAIQSMFCPVVGCSHQITQNGLVMEETVKRELRKKSREVQKPDDITEL Pucgr2 HLKTAISDINLL-VGDLAEDQLLNDFDQHARDLIEAIHLVEIRQKELEDLRERVHRSDAHDQLCKHWNSLTRQKFAQNKRYKSFRERIWEFTEDGAMPPAKTESSGDAGGKQNYKCPLCIGQLNVPVVSEKCQHAFCKGCFEAYLCPNSGCSAMLDKNSVALADRIRQLLRRAEMREDSDDDDDE- Punst1 ----------------------LAELDNTMREVIDIDTEMKANEKALSELHQRVARGELVEVYEKTYRNSTRQKYGKHEEYVKYKEAVWEVD-EEAMPPINDDSDDEGGVTQDYKCPLTLTIMKDPLTSKLCHHSYSADAIREYLCPAAGCTVRITVGDLALAKRAKRFAERAARHESDEDDADEI Rhior3 KLSSVYDDITLH-CIDREEKSAITPYD---SELIRLENE-----------------------YDN----KSKDKYLTNDRFIAYRQHIWNVKSDEEMPPLTGDNTDDGRTKLSFKCPITTSWLEQPLTSKTCKHSFTKTAIIQLICPVSGCNKIVKKDILILADKVKRAK---AKAEEEA---TEF Rhoto1 KIKLIISSVLNT-ASEMAEEKWLKALEEDFRALIDRQAELKIRAKTLGELRDRVHQGDVAKLFEQQYRAKTRQRFIDNERYVEYRHLVWESFNGSAVPPVKKQSDDEGAETTTYRCPITLTVLEDPYTSTVCPHAFSGYAIKELLCPETGCSKRLTASTIGLARRVAAYKRRVKEGRTQEDDEDEE Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 TIKGYAQDIIEV-GEATADEKGIKDLDKVMRELIDVAADMNAHEMSLEDIHGRLVAGGLREKYKAAYNAKTRQKYAKVKEYATFREQVFQVEPDEPMPPVSEESDDDGGVSQTFTCPLTLGVLKDPHTSKLCGHSYSGAAIKDYFCPAAGCSTQLARSDVALARRVKLWERRQKRAQEKDEDVDEV Schpo1 NLLPGNQNVIKC-ALVAAENECLDMLDSGIRELLDAKQRLLLMQQSVDTLANKTSENSLLDIYTQEYEEKSYGKYGTQGEYIEFKKTIW-HEDGSDFPSMKTEQEADYSATFDNRCPLTLQPIVHPILSTACNHFYEKDAILSLLCPVVGCEARLQRSLLILERRLRRAQEISNLKEA-------- Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar --------LYEA-------SSKLDLVKCHISTLQKLDGEVQSTNFTLDQFETRV---EFDTDFQNDHKVDS-------QESLAFLKEQFPHKVNSEL-----ESDEDGPATQDFKCKITQMLMKDPMKNSVCGHRYSKAGIMQMICPIGGCGKTVRRNTLRFEKILKRFQRTMDSQQHESSNVETI Spipu1 KFGLLLQSSTEA-AVDLEDEQQITQLDASIKSYLDMVQELNSQKRILEDMRARLTAGDLVAWFEEEWEATDAARYHGNEEYVEFRRKLWEKRPNKPFPGENEQEEDDVSQNQSLVCPITQSLLEDPVTSNVCNTLLWKA----------------------------------------------- Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 KLQGMAMDLTEV-ATAVADEKELTQLDSLTKEVLDLENEIASRGDTLKDLHQLAARGNITERYEQDWNQKTRQKYARNEKYNAFKQGIWEAQPDVPMPPIVEDEEDDGGVVQDLKCPLTLTWLDKPVTSEVCGHSFSAESIIQMLCPASGCRQMICRNDLDLERKVKNAQRRAQRREED-SDAEEV Tapde11 QSQLVL--LEDHCATCLETGSRVEEVEEAVKEVIEVREDGVRVKDSVAALMADHNDGDAATAVLEEYRDKSVERYGAVPAYDAFKRRVFDVQPESPYPGTASGDDDDYRAKRNLKCPITMMTLHHPMRSTVCVHVYSRDALAEMLCPVAGCDKTLTADTVVMERRVRVQEDEEAREGEEDVDGSAV Thetr QSAGYARG-ARL-RTEFEEEELKRQLRSMLDTVLEAQIESLAHSKALREVMKSAEAHEAEAAAMASYQLRI-------AVLEEFKETLIEGV-----MEIA-DGDDDSTSSTRFICPISGQIMQDPVHGP-CGHHVDRPAI---LCPHLGCGRIINRRDLSILRAIRS--ANINDDTTQGLEVEDV Treme1 KTGVVSSVTREA-AKAFED-PAVEELDAAFRRLLEVREELRIKIRVLTEMAAELRQEDPDKIYQEEYRNKSRAKFQNLPEYQDFRAQIWEINPDDACPPVSREESDEGATTQTYRCPITLLQFVEPVTSNKCRHSYSRAAVEGLICPVAGCMATIEKKDLSLAKRTAEHAKRLQRRQEEEEDPENL Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 -MRKCIN--LEA-KLHHQE-------------------------ETLKQLNSQILDGSMVSYYNERQSQVSSTKYKRHDAYREFKQRVWDVHNDEEMP-LSEENSDEGRAKQSLTCPLTTVYFENPVMSKLCKHNFSYHAIIQLFCPIPGCDKHMSKDDLLLAKKVELAKRQETQRSKANTNYHVV Ustma22 NVRSLMAELNET-AEQVAECPELDQADADLRELIDAQAEKVIRRRVLEEIAQDLHTGNPASKYKEAYNEQTRKKYAKNTDYHNFKNTVWVAK-DGPMPLVIDDDDSDGGLVINFRCPLTTNILEDPLTNPSCNHSYSRSAVQEYVCPASSCSANLSLRMLALVKKVAAFKRREEER---RRQTSTV Walse1 -----------------------------MRSLVDLENRLQMKQETANEIVNEIENDKPANVFQQQYDNKTRQKYTNNSKIQSYYNAIWAVSPDEVVPNIKKDDDDSGSMRQNFNDPITLGLFQNPYTSTKCNHSYSFESIKAYLCPYSGCRSSIAMRDLRLAKRVQQIASRDAEEEHYEDN---- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3755.fasta_al_trimmed; alignment length = 159] Allma1 RQQLLRTALQ-LVPEYSFTDKTITEAAKLHEY-PSTLRGLAPPGMTKVVTHLRLEYMIPYIRQW-PDAVQLLAH-PNVPFALHHLHKLVDEMDTNYYSKRALLAGVYTSTELFMTKDQSPGFEQTWEFLNARFRDSVGKAASDVKTTLEWGASNLKGLL Ashgo11 QYKVLQRALEAHVPVLGFNERAIVRAAGDLGY-GSAVLSALAAAAQG-MEQLRVEADRPLAGQL-TQLLSILSL-PLVNTAMPELFRLSDDLDLAWYSKRAAVAMAYVSTNLFMARDRSPALEETLHFARRRLQQVLGTAYNNVEEFAWYQLLMAMNLV Aspfu1 QTTILSAALN-HVPKHGFTLEALTLGARDAGF-LDVSVQLLPLSVEEKTKLLRLRMNAEIKHQW-QSALALMSL-VNIPLSLSELHALSSDIDASWYTKRLSVSAIYASAEVFMTRDSSPDLSATQAFVDRRIEDNIGDKITGIKQCLGFMGSTAIGLG Aurde31 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 -SRLLEASLA-HVSEHGWTLQAIRQGARSLGY-TDVTHGLLTMGVTARVRTARLMMTGPYIHKW-PQAIALLSQ-PNLANTARDLGGLVDEI-LNWYTKRLILSGVYTSSELFMTTDKSKGFEQTYKFLDRRLKDVFGKAVSDVSNVVNFGVRSAMGIL Botbo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 ETSILRAALP-HIPTHGFTLNTLSLGAQDVGY-IPAATNLFPVGR--RVKALRLMGNKDVIHKW-QEAQSLLTL-PNLPTSLRELHSLSDEIDSSWYTKRASLSTIYATTELYMTTDKSEGFKDTREFLERRFRDSLGGVVGGISQWVGFTAMAGVNVL Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 DDQILTTAIK-YIPEYGFQSQCITKAIKELKY-PDSMNSLFTSSSSSRLIELRLSYNKPILNQLKTTGISQLIL-PNLTQGLNELYLLSDDLDFSWYSKRLSIASIYVSSELFMLNDNTKDFELTQRFIKQRVYDLLSDGYNNIEQWLGFNGISFINLI Cangl EFKLLSHTMENSVPQHGFTEKAIVNSLNAMKM-PSGMLTTIGAEASK-LESLRLKMDVPIASHL-TQMTAQLMV-PMTNVSLPELERLADDMDFAWYTKRAALATTYLASKAFMAQDKSHNFMETMEFAQDKLHKVLGDYYNNVEEFGWFTLMSAVNLT Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 RKALLSTALS-LVPQYSFSDQALAEAAKMLDL-PATVKGLAPLGVTKTVTHLRLEYMSPYIAQW-PDAVKLLTH-PNVPFALHHLHRLVDEIDTNYYTKRGLLAGVYTSTELFMTQDKSPGFADTWVFMDARFKDSVGMGASRLKSSLEWGANNLKGVL Cioin KVKILDNALD-FVVDHGWSRKALSCGAEQAGY-AGVAEGMFTIKVTSFIRSARLRMIIPCIGAW-PQAMGILAR-PIFPKSAEELAKMVDDIDINWYTKRGILAKLYGSTQLVMLTDQSPDFKDTWEFLDRRISDIISQSVKDNGSAFVETAFSGAKVL CocheC53 ETAILASAYA-HVPNHGFTMDALKLGARDAGY-LDVSTNLLPAGA--KVRTLRLRANAPIIHRW-QEALAIMSQ-PYVPASITELAKLADEIDSSWYTKRATLSAIYSTTELYMTQDKSHNFVETEQFLDNRLQDLVGGFMGSLGEWLNYTGHSAINVL Coere1 RLAIMDVALT-KVNEFGWTEKALISAATDLGY-SPMAHGSSKDSITEKLRFLRLRQTRPLIRRW-PEAAAILSQ-PNVPIAMRQLADLSSQLRIDWYAKRSALAATYLASELYMCEDNSPNFQATWSFLDRRIENM--STENSTLKFVNFTNQFSRNLF Conco1 NSELLEFALE-RVPQVGFTTQAIQRSCLSLDY-PDTPEQFEALNKDELLKLCRIELSESVIGKW-SEAVAFLTTSEGVKLLTLELYNLIDDFDMSWYYKRLMYSKIFTSTEIYMTQDKSPKFMDTYNFLETQLNDVMGNGLNNASDLIKFIGKNLIGSI Conpu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci --------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 ERAILTAACA-HVPAHGFSQAALSLGARDAGY-LDISTNLLPVGR--KVEALRLMGNREVIGRW-QEALAIMAQ-PYVPESLRELAKLSDEIDPSWYTKRASLSAIYASTELFMTTDKSQDFADTRKFLRRRLEEVVGGSLRSLGQWVGFTAGAGLNVL Debha1 ESIILTKSLT-YLPKFGFDSLCITQAIRDLKY-PDSLQSAISSEFNSRVIYLRLEYNQPIINKL-STGLSQLIA-PNMNQSLDELHNLSDDIDFAWYSKRLGFSSIYVSSEVFMLQDTSKDFHHTRKFVEDKVQAFLGGAYNDVEQWGTFNAISLVNLI Dekbr2 ENKILDKAYKEFVPQEGFTDLAVKKGAEAVGVNPSSLGAIFNVQASKRLKFLRLLLNKPIINNY-HQALGRMIL-PNIPESLKELHSLADDLDFAWYSKRFAVAGAFVQSELFMLADKSKNYQDTLQFATDRLNEVLGKAYNSFEEWALFNGISTLNLI Dicdi KIKILENSLK-YVNSYGWTSEAVSKACIEMGY-PPITQGILGLSKKEKVKLARLSMIKPFIGRW-SEAMQLLAN-PNIVNSSPSMLTLVDNIDFDWYAKRGLLIALYTSAELFMLSDTSVDHSNTWRFVDDRVDDLTIKFKNDIEETVGITLNTFLQKI Dmel RAKILDAALQ-HVPQQGWTRQAIILGAEESGY-PSVVHGMFPQEVEDFLVQARLEMVTPYKTHW-PQAMALLAQ-PHAPTALAQVLTLVDDIDFGWYTRRVGLATIMKMTELYFLQDKSPGHAQTWEFLKSRMDEAMTHTFQRSFNSAFITARNILGLG Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 EKSILAAAYK-HVPELGFSQKALGRGARDAGY-LDISASVIP-----RVEALRLMGNKEILGRW-QEALAVMAQ-PYVPESLKELAKLSDEIDPSWYTKRATLSMIYSTSELFMTNDRSPDFVETRQFLQRRLGEVVGGMVGSFGQWAGYTLSAGVNIL Galma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 VHSILDHALSHHVPRLGFTRSALVSSLSDLDL-SSSALGMFPYSVRQRVRAVRLGMTTKVGQHW-ADAIATMAL-PNLPYAVQHLAETADEIDLSWYLRRASLSLALSSSEIHLTQDSSVPFSTTFDFLCGRLDELLKDLGEEAGKRIEFGVRSARGVV Gloin1 PAEILKASLP-FVNQYGWSIDALSQGAKTLGY-PNISHGLFPLKVHQKIRFARLNLTKPYIRKW-PEALAIMAQ-PNVSMAVEHLAKLVDDMDMNWYSKRAILAAIYTSTELYMTQDTSPDFTGTYQFLNRRLQDSFGSL------------------- Hisca1 QSAILSVAVN-HIPEFGFTTRSLTLGARDAGY-LDVSLQLFPLSVEEKVLILRLKMNEEIIEHW-QDALATMSL-PNLAPSISELSALSSDIDSSWYTKRLSVATVYASADVFMTEDTSPGFSATKEFVERQLSDVVTRTLSDAKRYLGFVAGSVVGVG Klula1 QFKVLSNALNKHVPQYGFNERAIVQSLNELGM-GSSYLSVLGDSDKP-LKTLRLKLNEHVAPHL-SQLLSIMSV-PLASTALSELHKLTDDMDFAWYSKRIALSTAYVSSELFMAQDKSHNFQETMEFAQSKLNKVLGSMYNNTEEYLWFTLLSSINLA Lacbi2 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele KYDILEASLK-HVKNHGWSDTALKHGIADLEL-SDACISMFQLPETEFLKDARLELQLPFYDRW-AEALALVVS-PVVPRATEQFAHLIDDIDINWYTRRATVAAVYGMTELFMLQDESPDFADTWAFLDRRLADLLEKELRNVGDITKAAFIIARNML Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 PEAILKKALT-FVPEHGWTTVSIAKAAESMGY-PTIIHGMFPLGTQEKIKLGRLGMIAPYIDRW-QEALAIMGQ-PNVAMSLNHLAKIVDEIDMNWYTKRASLAGVYTTTELYMTTDKTPNYQATQKFLDRRFEDAVGKATNEVLQIAEFGAKSVLGLI Mucci2 RLEMLYATMP-FVAQYGWSMESLIHGARSLGY-PSVAHGMFPLSMNERVEILRLDMNKPYIQKW-PEALAIMAR-PNVAMSLKHLGDIADDIDMNWYTKRASLAAVYSTADLYMTKDSSPNYAETERFLKRRLDEAVGSSARQLGTMLTFGAKSMLSAL Mydma NAQILNVALQ-YVPKHGWTVTSIDEAVKELDL-SVSAAGIFKMSQAEFIEFARLQMIIPYIDSW-PQAMKLMAS-PAAPECIQLGAHLMDEIDMSWYSKRATLSAIYIATEIYLLNDKSQDFVNTWAFLHNRMKEVFEEFLSGTFSFFCAGITTAQNII Neucr2 EESILSAAYQ-HVPSHGFTPSALAAGARDAGY-LDISPTILPLSEWERVEAVRLSANAQVIGRW-QEALAIMAQ-PYVPPSLKELALLSDEIDPSWYTKRASLSTIYAAAELFMTNDHSPEFMDTRAFLNRRLREVVGGVFRNLREWVGFTATAGVNVL Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 QTTILTSALA-HVPAHGFTATALTLGARDAGF-LDVSVQLLPLSVEERVRGLRLRMNAEVKGVW-QDALAQMSL-LNIPLSLTELHALASDIDATWYTRRLAASAIYASAEVVMTRDPTPDLVETEAFVERRFEDRIADKLTGIGQCAGFGWNTAIGLG Phybl2 ---MLQATLP-YIQQHGWTMDAMTQGAKSLGY-PSVAHGVFPYTVNEKVKMLRIGMMKPYIKTW-PEALAIMAH-PNVPMSLKHLSEVVDDIDMDWYTKRASLAAIYSSTEVFMTQDVSPNHAETFRFLNRRLDEVIDASARQLGTMLAFGAKSMMGML Picst3 ESRILTKAIE-FIPEHGFHQNTITQAIRALGY-PDSLQLVITSEFHTRVAYARLQYNGPIINQL-GLGLSHLVV-PNVSQLLAELHLLSDDIDLAWYTKRVGFSSIYVSSELYQLQDSSEGFRRTNAFVDEKVHGLLGSAYNDVEQWGVFNAISTVNLI Plicr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo KALILDGALK-NVALYGWSETAISKACTDLGY-EPTLHSMF-LTQRERVKLARLSMIAPYINRW-AEAMQVLAH-PNIISSAPSMAGLVDEIDFEWYTKRGLLAALYTSSELYMLNDTTPEFVSTWRFVDDRVDDMVLKFKNDIGQSVSLTANMLLNKL Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ---MLKATMT-FVPEYGWSMQSLLHGARALGY-PSVVHGVFPLSMNEKVKLLRLEMNKPFIKKW-PEALAIMAQ-PNVSMSLKHLGDIVDDIDMNWYTKRASLAAVYSATELYMTQDLSSDYIETEKFLQRRLGDAIGSTANQ---------------- Rhoto1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 EHEILEASLS-FVKEHGFTQKALLEGAKLRGL-DNAPKEMFPLSLKEKIIYARLKLTFPIRKHW-GNALAILKE---------------DKDKTHWMTYKSLIAAVYSSA---------------------------GNAILKV--------------- Sacce1 QYKVLSLALQKFVPEHGFSERSIVESLNELGY-PSSMISSIGTPQYK-LEHLRLEMDKPIGGHL-SELMSQLAI-PLFETAIPELHRLSDDMDSAWYAKRLAVSSTYIGSKLFMAQDKSHNYKETFTFAKDKLHRVLGEYYNNTEEFAWYTLMSTVNLI Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 KALILENALE-HVPQLGFTEDAIVQGGQALGY-SNLSKALFPIPETSRVVQLRLQGNRDIVQHL-PQMIAICTY-PNLRKSLSSLAELSDEIDFQWYTKRAAISAIYSASELFMSRDTSPNFEATYNFVQHRIQHALNDLRNDVLEWGSFQLNAVRSIL Sorma EESILSAAYL-HVPAHGFTSSALVAGARDAGY-LDISPTILPLSEGERVEAL---ASREQGGYW-TVAGAIMAQ-PYVPPSLKELALLSDEIDPSWYTKRVSLSTIYAAAELFMTNDHSPEFMDTRAFLNRRLREVVGGVFRNMREWVGFTATAGVNVL Sphar ---------------------------------------------MERLKYARLAMTEPYAHKW-PEALVAMKMSPYIQSLLGALHTDINEINFDWYTGRTALSTVYTATEMFMTQDRSPHFEATYQFLDQRLDDLFGFSMHAVSSEFGYIYLSALSLT Spipu1 ATHILEASLK-HVPQHGWTVQALGAGASDLGY-PSVLHGLFPMKITAKIRTARLKLTGPYISRW-PEALALMGQ-PNVPMSLGNLGELVDDMDMNWYSKRTLLAGVYTSTELYMTQDRSPDFEETWKFLDRRLQDVIGRTASEVTNYLQFGVRSAFGIL Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 --------MH-HVPEQGFTIAAIERGATDSGH-LEITRNLFTVGK--KIRHLRLRANQPYIDHW-QDALAVMSM-PNVPASLQELHDLSDEMDMAWYTKRMSLSTVYASTDMFMTQDKSENFQNTWEFLDRRLNEVIGSSIGEITQFVGFQLWQAGNIL Thetr KTDIINAALE-AVPRLGFTREAVRAGVASMGY-APTLEAIFPDAPPERLAAARLEPHARFSSDVMAAALAQQVAVPNVAPAARELALMADEI-AEWSQRRMAVAGVYALSQTYMLADPSAHHADTWAFVDRWSAKALGSWWHSLHVPIANAPPAAVETS Treme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 DRDILAAAYK-HVPEHGFSLRAIGLGARDAGY-PDISASVLPVGE--KVAALRLMGNKDVIHRW-QEALAVMAQ-PYLPKSLAELAALSDDIDPSWYTKRAALSMVYSSSELFMTNDRSPNFLETRQFLHRRLGEVVGSTLGSVGQWVGFTLNAGVNVL Umbra1 ---LMEAALP-FVATHGWTTETISLGAQKLGY-PSIAHGLFPLSATDIVRLARLEMTRPYIKRW-PEALAVMAH-PNSVMSFTQLGKLVDDIDMNWYTKRASLAAVYTSTELYMTQDVSPNSVDTLGFLQRRLEQAVGSGMKQLGTMLDFGARSFVGMV Ustma22 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 QYAVLSHALKVSVPVVGFNERAIVHSLNQLNY-PSTMLSVIG-SSEE-LEDLRLELNVPIAGHL-SQLLSHVSV-PTVDTALPELHRLSDDLDFAWYSKRLGISCAYVSSELFMAQDKSHNYEETFQFARDKLQRTLGEYYNNTEEWLWYTLLNSINLA [Cluster3757.fasta_al_trimmed; alignment length = 146] Allma1 AIPDVHRQIADFIVEIEAKLGRIIDTGQRLLPVRSETVVFESDMTVAQHKAFNGVLNQLVYRHSKEIDVFYEGKTRQ-VLKQRLASLDVYCPSDYRISINLEIPRHKDRLSYT-HEQVDLTQVHELEVLLENIVHLVENVRLLADK Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 -------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 PFDEIIRFIADWIIEIEAKVGVLRESKARILPVVTETVLFESSMPLAQHRQFNTMLNQLLYRHLRVVDSFYDAETNQ-VLKRRLDDLNIFCPNDWRVSINVEEPRHKDRMQYT-HQHLDLTQVHELEIFDELVRVFVNNCRLMIRN Batde5 -------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 PLDEFMREVADWIIEIEAKVGLLIDTRARLIPVQVETIIFEADMSAAQHAHINQLLNNLHYAHTRQLDSFYDEKTGE-VKKIRVAHLNVYSPKDWRISISAEMPRRKDRITYT-HQQVDLTQVHELELFDELVRVFINNTRILVRN Botci1 PPAEITRLVADFLIEIEAKLGQLVSTNVRLLPVRSETVLFKSTMTEAQHRGLNEFLNKKVYLHRRETDKFYDQKTGE---KARVADLDLYFPSDCRISINFEMKRNKDRLSYR-QSQVDLTQVHELEIYFKLVDGFIDNVRLLART Caeel -------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 VTPDIHLAVCNFIVEVEAKLGRLVDGDQRILPVTCETELFVSNMDMGLHRHFNRMLNELVYTHTILVDRSYDKKSGA-VVKTKLAHLDIYVPNDYRVSVAIEEPRVKDRISYA-HAQVDLTMVYELEVLKENIVHLVNNIRLAGRG Cioin -------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 IYDDVSRNVCDFILEVEARWGQIIDTNQRLGFWRTETVLFESTMTAQQHKRMNLFLNAQVYRHTYETDMFYDKNTGE-FLKHRLGNLEVSSPKDYRIGINLEIDRQKDRMSYSWLGQVDLTQVHELELFESLINGMMNNLRVLSRE Coere1 PAEDIVRVVADFIIEIEGKLGRLVDTGQRILPVVSETALFESDMTLQQHAMFNKLLNQRVYKHTREVDHFYDKESGE-IIKTKVADLNIYSPRDIRITINEEQTRHKDRLSYK-QDSFDLTQV----------------------- Conco1 PLETNLKLISDFILEIEAKFGIIIDTRQRIFPTMSEVVLFESNMTEFQHRHFNQMLNYQVYEHLRHIDTFYDQKTQQ-IIKSRIANLNIHSPMDFRISLNIETPRNKDRLSYT-NEKIDLTQV-----FVKFLYSFH--------- Conpu1 PIDEFICEIADFVIEVEAKIGVMRDSGQRLLPLLVETILFESNMSAMQHKHFNGLLNELMYKHVKLVDSFYDEKSGT-VIKMRLGDLNIYSPKDWRVSVNLEVPRRKDRICYS-HENIDLTQVHELEVFDELIRAFVNNARILVKN Copci PLDEFIKEIADFVVEVEAKVGVLRETGSRMLPVLVESILFESNMSAHQHKHFNTLLNNLKYSHLYLVDSFYDEKTRE-VVKIRLGDLNVFSPKDWRISVNLEVPRRKDRMCYS-HEIIDLTQVHELELFDELIRAFVNNARILVRN Croqu1 PYDDFAAEVGRFVIEVEAKLGILCPAGQRMFPIGTEAPLFVTNMSANQHKAFNGLLNERVYSHTREVDEFFCQNTGE-VRKEKLGSMDITCPRDFRISVNLERPRIKDRLSYA-HQQVDLTQVHELEIYLTYLQVWLNTVRLLIRN CryneH991 PRNPFTSVVGDFIVEIELKLGTFMTQPRRIMPTLSEMIIFVSTINHLHHRALNELLNRAVFSRSKLADSFYDMDNGH-VVKRRIADMNVYCPGDFRISVNTETPRYKDRACYR-HQRVDLTSVFELEIFDEILQNVLDSARMLVKN Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 PRNDFNKLVTEWIIELELKLGNIWDKDQRILPVNTESVVFQGGMPQKSFKDIKEFLQGLV----RRKDKFIDVKTKR-RVKQRVSDLFIYMPGDLRLSMSLELPRDKDRVSYI-HQRLDLTKVYELELYVDLVQAFLDNGRIISRQ Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 PLDEFIREIADFIVEVEAKLGLLKYDNVRVFPVRSEAIIFESNMTALQHKHFNQRLNQLEYQHSYLIDSFYDEKTGD-VKKIRLGNLDIFSPKDWRVSVNMEIPRRKDRMSYS-HEVIDLTQVHELEVYDELIRAFVNNVRVLVRN Fusgr1 -------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 PLDEFIKEVADFVVEVEAKIGVLRDSGQRLLPVLVETILFESNMSVHQHKHYNNLLNGLKYNHLHLVDSFYDDKTGT-VLKVRLGDLNIYSPKDWRVSVNLEVPRRKDRLSYS-HEKIDLTQVHELEIFDELIRAFVNNARILVRN Ganpr1 FVDDITRRVTTWLVEVEVKLGTIRYTHQQLLPVDCETIIFESAMSAEQHKRFNATLNRRVYRHFTELDKFHNRKQGD---KVRLGDLNIYCPNDYRISVSREMKRLKDRLSYT-CPSVDLTAVYELEVAYEAVRGLLNQARLLARR Gloin1 PNNDFVRVVSDFLVEIEAKLGVLLDNRERILPVFCETVIFESNMTLEQHKSFNELLNNRFYKHTYEIDSFYDRKTGE-IVKIRVADLNIYSPNDYRISVNREIPRNKDRLSYT-HQKIDLTQVHELEVYIEIVEHFLNNIRMLAKK Hisca1 -------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 PLDEFIKEIADFIVEVEAKVGVLKDSGQRVLPVLVETILFESNMSVHQHKHFNSLLNNLKYSHLYLVDSFYDEKTGT-VIKIRLGDLNVYSPKDWRVSVNLEVPRRKDRMSYS-HEIIDLTQVHELELFDELIRAFVNNARILVRN Lenti61 PLDEFIREIADFIIEVEAKIGVLRDGGQRLLPVLVESILFESNMSARQHQHYNILLNKLKYEHLHLIDNFYDEKTSQ-VRKVRLGDLNIFCPKDWRVSVNMEIPRKKDRLSYT-HQAIDLTQVHELEVFDELIHAFVNNARILCRN Malgl1 -------------------------------------------MSMRQHRVYNKLLNELVYRHRKETDSFYDTSSQQ-IVKQRVADLNVYCPNDYRISINTETPREKDRLSYA-QQQVDLTQVHELEIFEDHVLVLLNNIRLLIRN Mellp23 AYDDFVASIGRFIIEVEAKLGTIKPVDERMFPVENESALFETNMTESQHRSFNELLNLRVYSHSKDIDEFYSQGNGE-IKKLKLGSLDITCPSDFRVSVNLERPRIKDRLSYE-HQQIDLTQVHELEVYLIYLKVWLNNVRLLIRN Mnele -------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 IPDDVVQAVADFLIEIEAKVGILIDTQQRIMPVQNEVVLFSSDMTVAQHAHFNRCLNKSVYKHTYETDQFFDQKTNA-VIKRRIADLDIFSPRDYRISVNVEEPRKKDRVSYQ-LNKIDLTQVHELEIFLEITANFINNIRLIAQG Mucci2 -------------------------------------------MPLEQHRHFNKILNDMVYKHTIETDKFYENATGK-IVKVRVADLNIHAPNDFRISINRELPRNKDRISYQ-HGAFDLTQVHELELYTQMIEVFMNNIRLLSRY Mydma -------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 -------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------VIKVNIGHLNIYLPNDLRISINIEEKRQKDRLSYK-SHQIDLTQV----------------------- Pench1 -------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 PVDDITRYIGDFLVEIEAKMGVFIDTNSRLIGALTETVLFESDMPLEQHKHFNQLLNDRTYKHTRETDRFFDQQTGK-VVKKRLADLNIHSPADYRISVNLEIPRHKDRLSYT-HGTFDLTQVHELEIYVQMIERFVNNIRLLSQS Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 PLDEFIREVADFIVEVEAKVGVLRDSGKRLLPLRVETILFESNMSVHQHKHFNTLLNKLKYAHLYLVDSFYDERTGA-VTKIRLGDLNVYSPKDWRISVSLEVPRRKDRLSYT-HEVIDLTQVHELELFDDLIHAFVNNARILVRN Polpo -------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 PFNDFTWTIAQFIIEVEAKLGTIRDSSERMYPIATESPIFQSDMPPKHHATLNRLLNQRVYLHLKEVDEFHGKNPQS-PPKEKLAHLDIHCPGDFRISVNVEHPRIKDRLSYS-HQQIDLTQVHEVEVYLLMVEVLLNNVRMLIRN Punst1 PLDEFIHEIADFVVEVEAKIGVLKDSGMRLFPVLVETILFESNMSAAQHKHFNTLLNKLKYTHRYLVDSFYDEKTGT-VLKIRLGDLNIYSPKDWRISVNLEVPRRKDRLSYS-HENIDLTQVHELEVFDELIRAFVNNTRILLRN Rhior3 ----------------------------------------------------------MVYKHTNEIDRFY-------IVKERIADLNIHSPNDFRISVNVEHP------------------------------------------ Rhoto1 PIDEFTREVADWLVEIEAKIGLLVDGGMRVLPVPIETILFESNMTVNQHKAFNQLLNSRVYSHTRELDTFHDQK-DK-SKKVRVADMNIFSPKDWRVSVSLEMPRYKDRISYS-HQQVDLTQVHELEIYLEMVQVLLNNIRMLIRN Rozal11 PTNDLVLTVSDFLIEIEAKIGHLIDTHQRI-------------------------------------------------------------PNDCGI-----------------NN-------------------------LFIQS Sacce1 GATEFHKHVCKLAIEIEMKFGVITDTHRRMKPFIVQNR-LVSNVPEQMFSSFQELLRSKSQVQKYTKDSIYDLRNKE-LKKVRVKDFLIRYPQDAKISISLEVPRTKSRSTYTFNDHLDLTKVHEVEVFNEYMCSFLNASD-LIRK Salro -------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 -MD------------------------MRLLPVLVETVLFESNMSMKQHQHFNHQLNKLHYAHHYLVDSFYDEKADNRVVKIKLANLEIYCPKDWRVTVSLECPRRKDRLSYK-HESVDLTQVHELELFNELIRVFVNNARILVKN Schpo1 IVPDTTKVISNFLVEIEAKLGTLIDTQNRFFPVMNETILFESDMTASEHKYLNEFLNQAFYKHTKQVDLFYNQSDNQ-VLKRRVADLFLYCPNDIRISISDELPRLKDRVGYV-HQKIDLTKTHELEVLFRRVQLFMDNVRILRRE Sorma -------------------------------------------------------------------------------------------------------------------------------------------------- Sphar -------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 PEEDIVLTVSNFILEIEGKLGLIIDTGDRILPVSSETVIFDSNMTMAQHAHFNRILNAVVYVHTKEVDHYYDQKSGQ-VKKQRIADLEVHLPNDFRISISLEIPRQKDRLSYS-HERVDLTQVHEVEVFADYVDIFLNNLRYLSRK Sporo1 PIDEFTREVADWLVEIEAKIGLLVDGGHRVLPVPTEAILFQSNMTIAQHKSFNQLLNARVYSHTRELDTFHNEK-----KKIRVADMNVFSPKDWRVSISLENPRRKDRISYS-HQTIDLTQVHELEIYLKGVQAMLNNVRLFLFC Stehi1 PLDEFILHVADWVVEVEAKIGLLKDSGRRLLPVQVETVIFESNMSAKQHMHFNTLLNKLKYNHLHLTDTFYDQKTGQ-VLKVRLGNMDIYSPQDWRISVNIEIPRKKDRLSYS-HESIDLTQVHELELFDELMRAFVNNARILVRN Tapde11 PLNDLTSLV----IEVEAKLGRITDSGQRIFPVDSNVLLFESNMTDEQHSRFNRHLNREVYLHTRLTDEIYNDADGS-VVKENITHLNIICPRDIRVSINLEHKRKKDRLSYR-LPQIDLTKVFELEVFEDLVTAFMGTVMKLNRV Thetr AHAEMAAAVASAVLEIEAKLGFLALPDSRIVGVKGEMMLFNSTV-ASVFDRFKNLFNRLVRYHKKSIDRKFDPVRGLASRKKRLGDIDVWCPSDLRISTSSETAREKERRTYT-FGRIDLTEVRELEVLFSLVSKFMHVVRIQVGD Treme1 PRNEFTKMIGEFIVEVEIKLGLLMGVARRVMPTMTEMIMFSSNMTKTQNQSLNRLLNSATF-RAQHVDSFHD-KNGN-VVKNRIGDLNVYSPQDWRVSVSTEEPREKDRACYR-HQQVDLTVVYEIEIFDEILQSFLDTVRMLIRN Trire2 -------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 PMNDTVQYVANFLIEIEAKLGTIIDTRQRLLPVGTETVIFKSDMSLNQHKMYNQMLNDMVYKHTRERDRFFDQQSGE-IVKTRIADLNIYSPNDYRISVSIENPRNKDRLSYS-HGQFDLTQVHELELFASMVEVFLDNARILSKR Ustma22 PLDDFVTIVGDWILEIEAKIGQIISTGERILPVRNETIVFESQMSASQHAHYNRILNSLAYHRRKEIDYFHDAETLA-IKKQRIADLDIYCPYDYRISINVELPREKNRLSYA-HQIVDLTQVNELEIFDDQVLIFLNNIRLLIRN Walse1 PSDEFIKEVSDWIVEVEAKIGIFVDTGQRALPVAVETILFISDMTISQHKHYNKILNDRTYAHSKELDSFYDLRTDQ-VKKVRVADLAIYSPKDWRISINMEIPRKKDRLSYT-QQQVDLTQVHELELYDELIKVFVSNVRLLVRN Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3760.fasta_al_trimmed; alignment length = 334] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 TIFVGGITEGAGGDEGIEKILSAGNLRRWIRFGFAEYEDPESLGTAVEILKDSTLLVVVDDSSLSYLEQYENEDELSDPEMRETVAKEIAAFRERSNRRDEELERRRQEKREAEMEKQFLDQERRWLNRERSRTAALEREKKRDKEEEARRYREWEDYYADRGAWRAAFRAREISNDEADRAAEERERARSAQQADDFLARQAEELEFKLSLEDEEEPQTARRPLIPIKSDEERAQAARQLAAEIPTDKEGLWKWDVKWEFVDEVLREQLKPFVEKKIVEYLGEQMLVDVVEEHVRKHGHPQELVEQLEE-----------VRSA-KIMNPQQS Aurde31 TVFVGSISGGIT-DAFLNQLLACGPVRSFKRFGFAEFEDPDSVARAIDLLNGKQLLVKADERTKTFLQFHQAPPHLHDENQRGLVISEIAQFRERAAKKDEELERERKDQRAREEHDSFRDRERRYEGRERRKMTDLEREVTRERQIRDERLHVWELFYTDRARWRARVLLSEREADERSRDMEQRQAEELRKASEAFLAQQMEEMQIKLTVDDDE--EKRKMPLVKLDSEEKMRERLEKIRESIPRDKEPLFKAR--------VIDKKIEPLTRRKMEKYIGDEELLMFVIEHLKDKKGPQKLLEGLEPVLME--EAEEFVIALWRVIFESMA Batde5 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 TLFVGSISTGIT-DAFLTSLFACGSLRSFKRFGFAEFEEPDSVSRALSLLNGKKLLVKADDKTRAFLDVYESPPHLQDENQRGLVISEIALFRERAAKRDEELERERKEARRRDEEASLRDRERRYEPRERTRIAQIERVISRDAAIEEKRLEVWELFYVDRAKWRQRHLATELAADASSRALEARQAEHLRAESEAFLARQMEEMRVRLSIEEEE--EKRKGPMVKLDGVEARKERLEKVRNGVSNDKDVLWKTKIRWEALPDLIDTKMERLAKRKMTSYLGDDDLVMFVLEHLKDHKGPQKLVEGLEPVLEE--EANEFVVSLWRVVFESGA Botci1 TIFVGGITEGAGGDEGIERILSAGRLRRWDRFGFAQYDDAESLATAVEILKDSKLLVFVDDNSLNYLENHQADDELSDAEMRETVAQEIAAFRDRSNRRDEELERRRKSKKEAELEKQYLDQERRWLNREKSRTAAVQREKEREDEDVAARLKEWDPYYVDRSLWRAIYVQREAAADERDRIAEQHERRRETSDADSFLDRQAEELEFKLSLEDEEEADASKRTLIPIKSDEERDQAVRQLAQEIPTEKDGLWAWDVKWDFVDDVIVEKLRPFVEKKIVEYLGEQLLVEVVEEHVRTRGKPQELVEQLEGALDE--EAEVLVKKLWRVIFFSES Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 TIFVGNIPDGVGGDEGMERILTAGKLVRWTRFGFAEFADAQSLETAAEIFKDTKLHIMVDDASIKYAEEWSKEDELADAEMREVVAAEIAAFRDRSNQRDSELERRRQKKRNDEAEEAYKKQLHRWLNTERRTVASLDRTNDYFKNMDAKQLREFDLYYRDHSDWREKVRGLEAKEDAIDREQERREMAAQKRQADAFLEEQGEELMFKISLEDEDLTDSKKRTLIPINTQEEIEEAQRQLARDIPNDKEGLWNWAVSWEHLPENINKDIKEWAANKVLEIMGEEMLVDAIVEHLKSRGAPQPLVENLEVALDE--EAEALVKKLWRVIYYSET Coere1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 FLFIGTITDFVS-DEAIEEIFICGELNSWLRFGFCEFSDLESIFKVLKYLNQRKLTIKIDNQHKKTIEEYSKEKDLAD------VGKEVSELRMLADSNDEDQILKKHEKETKELYEAYYERIKHWELREKDKLRTYEKDKATDAMDFEELMKTWHEYYKDRSEWRQPILKRELDQDERDRLQEKMEIEAKNKRTGSISDTNTNE-ETKLTLSDDE--SKAQRKLVPLESEARRKKKIKTLVDSIPADKEPLFKWSIRWDQVDSIYS-KLKNFTDKKIQEYLGEPQLVKFIMDGVASQKSPYDLVNSLDGALDQ--DSELFVLKLWRLIFESEA Conpu1 TLFVGSISGGIT-DAFLNRLLTCGPVKPIKRFGFAEFDDADSALRAITLLQGKKLLIKADEKTKLFLDAFSAPPHLHDETQRGLVISEIAQFRESAAKRDEELEEERKEARRREEENSYRDRERRYEPRERTRLAAIERSIARQQAIREARLDVWEMFYVDRARWRARRVALEEQHDSESRMYEEREAENLRIESEKFLARQMEDMQVRLNMEEEE--EKRKVPLVKLD-GDKAKERLKDIQQNVPHDKESLFKGKVRWDGLSDMIDRKLEPLIKRQMVKYLGDDDLIMFVLEHLKDHKGPQKLIEGLEPVLEE--EAQEFVVSIWRVIFESMA Copci TLFVGSISGGIT-DAFLNQLLACGTVKPIKRFGFAEFEDPDGALRAMELLNGKKLLIKADEKTRLFLDAYASPPHLHDETQRGLVISEIAQFRERAAKRDEELEAERKEARRRDEENSFKDRERRYEPRERQRIQAIERAIARKEAQREKRLDIWELFYVDRSRWRARRLEAEEAADEKSRKYEEQEAENLRKESEAFLARQMDELQVKLNVEEEE--DKRKVPLVKLDSSEQIRERLLRIKASVPHDKESLFKAKVRWDGLSDMIDRKFEPLVKRLMTKYLGEEDLILFVIEHLKDHKAPHKLVEGLEPVLEE--EALELVISLWRIIFESMA Croqu1 SLFVGSIAEGVD-DAWLERLLVAGHLVSLRRFGFAEYGDPESVLRCLKVIDGKALMIKPDDKTKARLNAYEAAAHLQDEESRGLITREIQFFRERAISKDEAEEKAREDRRKRMNHLEFKDRERRWETRERNRAQTIQRENQREKSIREVRLANWELFYSNRSKWRQTFRQREEKSDRIDEELEQEQLEAIKKESEEFLNKQAEMIAIQLSFEDDE--DRRKRALIPLT-EDKKKKKMRELVSSIPNDKDALWQLTVDWKWLSEIITEKLVPFANKKIIEYLGEDELVSAIIDHLRAHKDAQGLVTELEPVLAE--EAEEFTFKIWRLIFELRA CryneH991 KVFVGGIAPGIT-DETLESLLACGPLHELKRFGFAMFENPEVVLRCIRCLNGKKLIVKADEKTQAFLEEFESPAHLQDEEQRVAVLGQIAVFRENAAKRDEEEEEFRRRKIQMDKDIALRDAERRVEARERARLDALSREMNYRQTQKDELYARYELFYVDRAQWRQKFRQNEYQADLRDRQHEEDERQALERESEEFLKKQMAELAIKLAIDDDE--EKKKGTFVRLDKRARRNARLLDVKKGVPSDRRSIWKFPVEWAAVGELVQNKIKPFVHQKIKNFLGDEDLADFVLEHLRDRKGANDLVDGLEPILAE--DAESFVLQLWRLIFESLA Crypa2 TIFLHKVPASLGGDEGIEKFLLVGRLRRWDSFGFAQYDDTESLSVAVELLKDAKLQVAVDESTIKYLETWEEEDELADAEMREVVAQEIAAFRERSNRRDEELHQRELSRQKAEDDKLYLEAERKWVNRERQRAAALERETDREKAEDDEREKNWHPYYRDRAGWRAQDRGEEEGRDEADRRAEESQRRREAAEADSFLNQQAQEMEFTLSLDDEEQ-ETTKRQLVPIKTEEEIQNAVKSLAQEIPATQDGLWAWDVKWDYLEDIITEKLRPFIEKKVVEYLGEQLLVDVVEEHLRKHAQPAELAEELEGPLED--DAVDLVKKLWRVIFFTES Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba SLFVGSISPRLD-DRSLEAMFTVGSFVKWERFGYASFGNLVGVKRALVLMNG-ALKVTADKTVTAKLVAEREPSEGQDAAARAAVAQAEADLQEEWTTRLEMAERRRQQERQKEQENLFRSSQLRWKDLEGAYLKSLANGRNFLAARQRRLL---LPFYTNRERYRERDRAREEAADLRDREKEEAELQQDRHTTDAEIERRAREDLVGVVLEDDVA--AAKRHQPPSSSVEEFRTRLEQV---LPTGHAILMQLPVEWPLVTPLLDAYVRPWADTAVQQSLGDPELVSYLVDMLGSSPSANNLHEQLAPLFDV--ATDSFFAGIWRLLIGTWT Fomme1 TLFVGSIAGGIT-DSFLQQLLTCGTLVSFKRFGFATFDSPESAARAIKLLDGKKLLVRADELNKGMIDAYFAPPHLHDETQRGLVISEIAQFRERAAKRDEEMEEERKEARRRNEENSFRDRERRYEPRERRRITEMERSIARQRATRESRLHVWELFYTDRARWRVRRLRAEEAADEQSRSYEEKEAENLRRESEAFLARQMDEMQVKLNVEEEE--EKRKVPLVKLD-GEKAKERLEKIRENVPRDKDALFKAKVRWDGLSDLIDRKLEPLIKRQMTKYLGDDDLVMFTVEHLKDHKGPQKLVEGLEPVLEE--ESVEFVTSIWRIIFESMA Fusgr1 TIFIHQISEGVGGDDGIQRLLAVGKLRKWDSFGFALFDDPWSLSSAVKLLHETKLQVTVDESSLKYLESY-EEDELADAEMREVVAQEIAAFRERSTQRDEELYRRYKSKKDEEDDKAYLEAERKWSNRERSRQAAIDRERERERQDAEEREKAWHQYYRDHSVWRAADRADEEAQDEADRRAEHDEQRREKVEADSFLDKQAEELEFKLSLDDEEA-DSTKRQLIPIQTEEEISQAVRSLAQEIPSDKDGLWGWSVKWDYMDGVIKDKLRPFVEKKIVEYLGEEMLVEAVEEHLRAHGTAAALVEELEGALDD--EAEDLVKKLWRVIFFTES Galma1 TLFVGSISGGIT-DSFLNQLLACGPIKSFKRFGFAEFEEPAGALRALMLLNGKKLLVKADEKTRVILDGFSTPPHLHDETQRGLVISEIAQFRERAAKRDEELESERKEQRKQEEELSYKDRERRYEPRERTRIQALERAIARETAQKEARLDIWELFYVDRARWRQRRLEAEEAADEKSRRFEEQEAENLRRESEDFLARQMDEMQVRLNVDEEE--DKRRVPLVKLDSGEQTKERLERIRQSVPHDKESLFKAKVRWDGLTDMIDRKLEPLVKRIMVKYLGEEDLIMFVLEHLKDHKSPQKLIEGLEPVLEE--EAVELVVNVWRIIFESMA Ganpr1 TVYIGRITDGVA-DEHVEKLLVCGPIRAWKRAGLVEFETLEGMHKCEMLLSGKSLIVTIGEAAKMATEEFKRPDELDDMENQELVLKEIATFRRQQARREEEEEAKKEARRQKEMEIAFKDREKRWESRESARFRKFDQEDLRDRDDEGRRLREFYEWFRDRQRWRRIHRARERADDEQDRKLEAEEIEAEQRAAEALQAAQVAT--VTLEVDGDRD--VPTRPFAPPATAEERKRAQTELVDEIPAAREPLFGWRVRWEVVDELLTTKLRSFISRKLQSLLGVPDIADHVVDHLRQRKTPDALWEEMKEVLDE--ESERFVCLVWRLVYETES Gloin1 --------------------------------------------------------------------------------------------------------------------------ERRWQHREETMATNREREAERDLDVRERKLAEWEEYYKDRSRWRQQFRARELAMDEADRLREQQEIELEQHREEAMEAELNNE-KPKLTLDDEEGIERKRRILVPLEKTEERKKKIKELVATIPTDKEGLWNWNVKWEELDEILSKKLQPFVSKKIVEYLGEDELVSFVIDHLRNKKPAEDLTKEM-------------------------- Hisca1 TIFVGGITEGVSSDETIERILTAGNLKRWIRFGFAEYEDPESLSTAVEVLKDSKLLVVFDDSSLKYLEQFESEDELSDAEMRETVAKEIAAFRERSNRRDEELERRRKEKKAVEAEKQYLDQERRWLNRERSRTAAVEREKNRDKEEDIKRLREWEEYYADRGVWRAAFRNREVSMDEADRATEERENARTQQQADDFLAQQAEELEFKLSLEDEEDTGATRRPLTSIKTDEERAQAARQLAADIPSDKDGLWNWEVNWEFVDEVRGEQLKPFVEKKIMEYLGEQMLVDVVEEHIRKRGHPQELVELLEEALDE--EAEILVKKLWRIIFFSES Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 TLFVGSISGGIT-DAFLNQLLACGPIKSFKRFGFAEFEDPDGALRALELLNNKKLLVKADEKTRAFLDAYQAPPHLHDETQRGLVISEIAQFRERAAKRDEELEAERKEARKKDEEISFKDRERRYEPRERTRIQALERAIARERATKEGRLDVWETFYVDRARWRARRLEAEEAADEKSRRFEEQEVENLRRESEDFLARQMDEMQVRLNVEMEE--DKRRVPLVKLDSSEQTKERLERIRQSVPHDKDVLFKAKVRWDGLNDMIDRKFEPLVKRLMMKYLGEEDLIMFVLEHLKDHKGPQKLVEGLEPVLEE--EAIELTISVWRIIFESMA Lenti61 TLFIGSISGGIT-DSFLNELLACGPISSFKRFGFVEYQDPDGALRAMDLLNNKKLLVKADERTKVFLDAYSAPPHLHDETQRGLVMTEIAQFRERAAKRDEELEQERKEARRRDEENSYKDRERRYEPRERARIQALERAIARERAMKDARLDVWEPFYTDRARWRARRLASEQAADEESRMYEEREADNLRRESEAFLARQMDEMQVKLSVEEEE--EKRKVPLPRLDGGEKAKERLEKMRGEVPRDKETLFKSKVRWDGVSDMIDRKLEPLIKKQMTKYLGDDDLIMFVLEHLKDHKGPQKLVEGLEPVLEE--EAAEFVISVWRIIFESMA Malgl1 TVFVGSISPGVS-DRWLVQLFACGGYRSFKRFGFADFSTLRDALRVLAVLHDKKLIVRADEKTSAFLGEFEKPSHLKDVNRRKHVLSEIEKFRSDAADRDERNEADRQRVEASRRARDARQAEHAYLEREQARLATWAEHTLTENA---RSMEAWESFWTDRRRWRAEARRREEEADRADRDAEKAENAEAKRQADAFLAELAPMAALKLHV------EGVQRRL----RDAPDHAHVIRLVQSLP--RTELWGITPAWTRVDL----HIAPTIDAGIAASFGVPDLQEAVLDKLREHANAQDVADVLEPVLDD--EAADVVDQVWRLLLPPP- Mellp23 -------------------------------FGFAEYGDPESVLRCMKVIDGKALMIKPDDKTKARLDTYAAAAHLQDEESRGLITREIQFFRERAISKDEEEEKMREDRKKRMNHLEFKDRERRWETRERNRAQTNQRDQQREKSIRDARLSNWELFYSNRSKWRKTFRQREEKSDRIDEELEQEQLEAIKKESEDFLNRQAEMIAIQLSFEDDD--DRKKRALIPLTVEEKKKKKMREIVSSIPNDKDALWLLTVDWKWLSEIIKEKLEPFANKKIIEYLGEDELVSAIIDHIRAHKDAQGLVTELEPVLAE--EAEEFTLKFWRLIFELRA Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 TLFIGSIAPGIN-KVAMEKLLTTGNLVKWKHFGFAEYADADSLLRTLRVLGQKPLLVKADEKTRQFLDQYEEPRRHTNEEQKELIAREINFFRERAALKSEEEEKARQERRNREAEHTFKERERRWEQREAERMRLYEKDKARDADYQAARFAQWEDYYRDRSRWRQAFLQKEQRYDDLDREEEKEEMAEAAKK-------------AAMEVKDVEMNE----------SISTTTEGAEKNVLDIPSDPQELWNWPVQWSVMEAILKEKIKPFATKIVVELLGEEDLTKYVVDHIRQRKPPQDLVSELRGALDN--DADRLVARVWKLIEETES Mucci2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEEE--EKKRRVLVPLDSSEERQRRVKQLIDSIPSSQEDLWKYTVKWDELNELIETKLHPFVSKKIVDLLGEDDLVKFVLQFIRERKGPDELVSELEGALDE--DALVFVMKLWRLIFETER Mydma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 TIFLHKIPDGLGGEEGVQKLLTVGRLRRWDSFGFAQYEDPDSLAIAVELLKDVKLKVEVDVNTTKYLEARKEEDELADAEMRETVAAEIAAFRDRSNKRDDELYQREVNKQKAEEEKLYLEAERKWVNRERQRAAALEREKEREKTETEEREKSWHMYYRDHAHWRLQERNDEQARDEMDRRAEEDERRKAEAEADSFLERQAEEMEFTISFDDEEQ-ETTKRQLVPIKSEEDLQKAVRALAQEIPADKDGLWAWDVKWDYLEEIISEKLRPFVEKKVVEYLGEQFLVDVVEEHLRKHQKPAELVETLGEALDE--DAEDLVKKLWRVIFFTES Orpsp11 NVFIGEIPEGIT-DEFIEQILVCGNIRSWKRFGICEFEGFEVLFRALRVIGGKEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTMKHIS-------------------------------------- Pench1 TLFIGGITEGAGGDDGIERILSTGLLRRWIRFGFAEYEDPESLEVAVEILKDSKLLVVVDEGTLTYLEQFESEDELADPEMRANVAKEISAFRERSNRRDEEIERRRQDRLKAEQEKQFSDLERRWLSRERSRTAALEREKKREDEEDEARLGAWVDYYADRSAWRASFRSREANIDEADRAAEERERVQSAKQADDFLARQAKELEFKLSLEDEEEPATTRRPLIPIKTDEERAQAARQLAAEIPAEKEGLWNWAVKWEFVDDVISDQLKPFVEKKIVEYLGEQMLVDVVEEHVRKRGSPQELVEQLAEALDE--EAEVLVRKLWRIIFCSES Phybl2 -----------------------------------------------------------------------------------------------------------------------------------------------------------QEFYVSRSRWREDVKRREEERDDEDRRAEQHELDEARRQETNVLNREPDEIT-KLNFEDEE--EKRKRVLVPLD-PEERAQRVKELIGSIPSSEQELWNWPVKWNELDELISTKLQPFVSKKIVEIVGEDDLVDFILEFIRNKKPPTELVSELEMTLDE--EAMMFVMKLWRLIFETER Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 TLFVGSISGGIT-DAFLNQLLACGPIKSFKRFGFAEFEDPDGALRAIALLNGKKLLVKADEKTRALLDTYAAPPHLHDETQRGLVISEIAQFRERAAKRDDELEADRQESRRRTEEVSFRDRERRYEPRERTRINALERAIQRERALEESRLDIWETFYIDRARWRARRLAAEEAADAESRQFEERETENLRRESEAFLARQMDEMQLKLNVEEEE--DKRKFPLVKLDSGEKAKERLEKIKASVPNDKETLFKSKVRWDGMTDMIDRKMEPLVKRLMMKYLGDDDLVMFVLEHLKDHKSPQKLVEGLEPVLEE--EAVELAVSVWRVIFESMA Polpo ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 SLFVGSIAEGVD-DAWLERLLCAGHLVSLRRFGFAEYGDPETVLRCLKVVHGKTLMIKPDDKTKARLDAYEAAAHLQDEESRGTITREIQFFRERAISKDEEEEKLREDRRKRMNHLEFKDRERRWETRERNRTQTNQREQQREKSIKETRLANWELFYSNRSKWRRAFRQREEKSDRIDEELENEQLEAIRRESEEFLSKQAEMIAIQLSFEDDD--DKKKRALIPLTSEEKKKLKMKEIVASVPNDKDALWKVEVKWNWLSEIINDKLKPFADKKIIDYLGEDELVVAIIDHIRAKKDAQGLVEELEPVLAE--EAEEFTLKFWRLVFELRA Punst1 NMFIGSISAGIT-DAFLNSLLACGPIKAFKRFGFAEFEDPDGALRAMALLNGKKLLVKADEKTKMFLDAYSAPPHLHDETQRGLVISEIAQFRERAARRDEELEAERREARRKDEENSFRDRERRYEPRERTRIQGLERAIARVRAVEEARLEVWEMFYTDRSRWRARRLATEEAADAESRAYEERETENLRRESEEFLARQMEEMQVKLNVDEED--ARRKVGLVKLDSGEKARERLEKIRLGVPRDKETLLKAKVRWDGLSDMVDRKFEPLVKRLMVKYLGDDDLVMFVLEHLKDHKGPAKLVEGLEPVLEE--EASELVINVWRVIFESMA Rhior3 TLFVGAIAPGIS-DEWIEKLLVCGTLKQWKRFGFATYEDPDSSLCALRVIGGKKLIVKADDNVRSYLENYQQLPGDADEEHQDSLARDLAMFKERAVQK-EEMERRRREKHERDVENAYRHREKRFENRENAQLREYEKDLKREIEEEEERLADWELYYSDRSRWRESVRRRDHERDEEDKRRELQEIEDEKRRESKILNREGDD-R-KLNFEDEE--EKKRRVLVPLDTTEERTALVKKLIDSIPSSQNELWSYRVRWEELDELIEQKLRPFVSKKIFELLGEEDLVNFVLKFIREKKGPDELVSELEGALEE--DALVFVMKLWRLIFELER Rhoto1 SLFVGSIVDGLE-NGWLESILVAGPVLSFRRFAFVEYAEAESVLRCLEVVNGKTLLVKADEKTRGRLDEYEKPQHLKDESHRNNTLSSIAQFREAAVKKDMERERERAEAEHRQQEVVYRNRERQFEQRERARIAAWEREQAREQGIAEERLATWELFYIDRIRWRKPHRLREQEADARDRAFEAQQVAALNEQSDSFLSQHADLFAVKLNLDEEE--ERKKRELIPLESRSEMERKAREIEAKVPTSKDGLWVWKVRWKRLNDIIKRRITPYANRLIVDYLGEAELLNVVNEYLRDHKGPQALLEELEPVLDE--DVTNFVVKVWRLAIETEF Rozal11 TIFVGSLHESVP-DDVIFRVLACGPVKKWNRFGFCEYLSADGVLRCLRLLETKQIMLRVDEKSKNYLERYKE------EDKAQALLNEIS---EAAAQSEEDQKEGHDDQHRKKRERDFIDRLRRWESKESGILRGIERDEEREMQRKDKYFSYFAEFYRDRSRWRKRDLVRESEYDMEDRRLEQEELRRQSQVSAEISPMETDEVSIKVGFESDEEIEHKRLRLMPIEVLENEKHRAQRLVQEIPVDKIDLFKYQISWDVLDKLISLKVKPWLNKKINELFGNEQFESIIIKSLLNKENPDILIKEISNEIEF-SNAELFVVRLWRIIFETEY Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 SLFVGSISGGID-DDFLNRLLACGPVRSFKRFGFAEYEDMDSAIRAIDLLTGKKLLVKADEKTKTLLDAHKSPPHLHDETQRGLVISEIAQFRERAAKRDLELEEERQEARRRDEEASFRDRERRYEPRERNKLTALERSIARERATRDVRLDIWELFYVDRARWRARRLEQEEAADLKSRQYEEEEAENLRRESEDFLARQMDEMQVRLNVEEEE--ERRKVPLVKLDTTEKAQERLEKIRTEVPKDKETLFKRKVRWDGVTEMIDRKMEPLIKRLMVKYLGEEDLIMFVLEHLKDHKAPKQLIEGLEPVLEE--EAVELTVSVWRLIFESMA Schpo1 MLFIGNIPKELD-DFWMDKILLSGKLASWRRFGFAEFESNEQFSRALEALNDTRLSLITDVENEGLYREWQTPINAADPELLPVIEEEIRSFRDQSAMKDEQAYYEEKRRKDQLEAEEYYARERRWMNREKARTAALEREAAREEEERVEKLASFDEYFVDRAAWRAVARAREEDADALDRKEEERELRTRGEGTENYVENGKLVTSFKIKIEDEE----------PQGNDAEKTKRLRSLIEKIPVEAESLWALPIDWSKVTELLKEEMQAFVTKKIIEYIGEDSLITFTIDHIRQHKGAEQLVSELDLALAE--DAPEFVSKVYRLILRSEA Sorma TIFLHKIPDGLAGEEGVQKLLTVGRLRRWDSFGFAQYEDPDSLAIAVELLKDVKLKVEVDANTTKYLESRKEEDELADAEMRETVAAEIAAFRDRSNKRDDELYQREVNKQKAEEEKLYLEAERKWVNRERQRAAALEREKEREKAETEERGKSWHMYYRDHPHWRLQERNDEQARDEMDRRAEEDERRKAEAEADSFLERQAEEMEFTISFDDEEQ-ETTKRQLVPIKSEEDLQKAVRALAQEIPADKEGLWAWDVKWDYLEEIISEKLG----------LSEG------GGHLRKHQKPDELVETLGEALDE--DAEDLVKKLWRVIFFTES Sphar ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 SLFVGSIADGIE-NGWLERILVAGPLLSFRRFAFVEYSDPESVLRCLSVVNGKTLLVKADEKTRARLDEYEKAEHLRDDSQRATTLSSIAAFRERSMKKDAKRERERAEQEHRLQEQIFRDRERRFEQRERGRILAWEREKMRERSIVDERLATWEAFYVDRVRWRRAVRQREEDFDARDRALEAQRAAQIAQQSDSFLAQHADLFSVKLSFEEEE--ERRKRELIPLSTGRDKEKRIMEIEDGIPRDKQKLFGWDVKWSSLNE---VRLSPV-------------LLVSIPVPLTRPSRRYRVLKTLR-----------FFFLVSSLVVDR-- Stehi1 NLFIGSISGGIT-DAFLNELLACGPVKSFKRFGFAEFEDPDSALRAMSLLNNKKLLVKADEKTRNFLDAYSAPPHLHDETQRGLVINEIAQFRERAAKRDEELEADRKEARRRDEENSFRDRERRYEPRERARIQALERTIARERASKDSRLAIWEVFYTDRSRWRARRLAMEEAQDAESRAFEEREVDNLRRESEAFLARQMDEMQVKLNVEEEE--DRRKVPLVKLDDGEKAKERLERIKASVPKDRESLFKAKVRWDGVTDMLDRKLEPLVKKLMVKYLGDDDLVMFVLEHLKDHKSPQKLVEGLEPVLEE--ESVELTISVWRVIFESMA Tapde11 TLFIAGIPPYFD-NLSLEKLFAVAKFQAWKQYGFVTYEEPDSLARALTILSSTNFIITQDPMSKLYMDDYKAEDELGDEEQRASIASEITSFRERSARREQDIAARRQLTIDDEENRHYIKEENAWLAREGLRIASLKSDLSRVVDSKNEKFEKFEEFYRDRVAWREVTRRQELEQDAHEAQSDSQIPSNHSGQPTDFQTK------VRLALEDDEQ--VAKRVLVPMQSSEALQKRLANIANSIPFSKPELWKYQVKWDLLDE---NKLRIFIAKKIVDVLGEEDLTSAIMALIHARKGGQDIEQELDAAIGDAAESEVTAIKIWRFILSLEL Thetr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 SVFVGSIAPGIT-DETLKELLACGPLHELKRFGFASFESPEVVMRCLRCLNGKALLVKVDEKTREFLDEFEAPAHLQDEEQRVAVLDQIAIFRENAARRDEEEEEIRRKRRKQEADALMRDRERQVESRERLRVERYNREMGQRRQYTDGIYDNWDVFYVDRQRWRQSARLREYQEDVRDRNVEADEMAALEKESEEFLKKQMEEFAIRLALDEEE--QKKQRTLVKLEQAAKRTARLLEIRERLPHERRRLFGFEVEWAALTELLQGKILNLVKEKMRHFLGDDDLVDFVLEHLRARKGPNSLIEGIEPVFAE--EAPPFVHDLWRIIFESAA Trire2 -----------------------------------------------------------DDTSLE-------EDELADPDMREVVAGEIAAFRERSNQRDEELWRRREAVRKAEEDKMYAEAERKWVNRERSRQAALERERERERHDLEDREVGWHIYYRDHAAWRTAERIEEEARDEADRQAERIEQSREQARADSFLDQQAREMEFKLSLDDEEV-ESTKRQLVPIQTEEEISQAVRALAQEIPSDKEGLWAWEVKWEFMDDVVRDKLRPFVEKKIVEYLGEEMLVEAVEEHLRKHGTAGELVEELEGALDD--EAEDLVKKLWRLIFFTES Umbra1 TLFVGAIAPGIS-DGWIEALLECGELVNWKRFGFAEYADPDSVLRALRVLGGKKLIVKADDNVRRYLDQHQQEPGTADAEQKDVISKEIAYFRERAAQREDEVERRRQEKREQEMDIAFRERERRWEQREAKMARNYERDANKELEIAEVRLAEWEDFYRNRDKWRGPVRDREAQADDRDRKREQDEIEEQRRRGLAAG-------A-KISFDDDE--TRKKRVLVPLDNPEERKRKVKQLIDSIPASQEGLWSWHIKWDELDNTLEKKLRPFISKKIVELLGEDELTQFVLDFLKKRQPPNALAKELEMALDE--EASMFVMKLWRIIFETES Ustma22 TLFVGSISPGVS-DTWLTRLLACGNLRSLKRFGFAEYADPDSVLRAIEVLHAKKLLVKADERTKRFLEKYQQPDHLKDEDQRATVLSEIEQFRQAAAARDEIEEKQRQERKKAAAQAASVDAERAYMIRERQRLAHWEKEQHRQRAETERRYEDWELFYTDRPRWRTSARRREEEADERDRAAEAEEMVRAQQETEKFLALQAAEMAIKLTFEEDE--SKRTGRLTHIKSPQDKARKLAQLTESLPKTSGELFAQSPQWEYVDELIQSKYRRWADAEIEDSLGVDELVTVVVEALQNRSDARAVVEQVEPVLAE--EAEAFVDKLWRVLVDSLA Walse1 TVFIGSISAGVS-DEWLERLLAAGNLVTLKRFGFATFAEPDSVLRAIKTLNGKNLLVKADEKTRAFLDDYEKPAHLRDEEHRQETLNMIEMFRQRLEREDERAENDRLARRLRDRELAFRDRERKFEGKERARLNEYDRDLARERANDSHKLLAVELFYDNRRRWRSQARRKEEAADEADRMAEINESEKVKRDTEAFLQQQAIEMEIKLSAEVDE--NMQKRKLVKLDREAARRVRLREIANGVSLDYVQLSKIDINWDAITDVISKKLIPIAESLMKEYFGDEEMLEVVSDQLKSHQGIDEFVETLEPVMLE--DSKTAAIKIWRLAFESIT Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3784.fasta_al_trimmed; alignment length = 87] Allma1 --------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------- Aspfu1 HRART-IVEVRAAQRTFEGAYVRTALSQFSFALVVLKIFTSEFYSTGALFAIYGTGVLIIGLFRRQFKTSGNAVLVLTALLIAL--T Aurde31 HKRYS-LVEIRARQRTFDGAYARTAIGSLAYSLVFLKLFDTRFYKIGLVFLVLAVMLAILAILRNRFLTAGWIVVAVTAVLLVL--V Batde5 --------------------------------------------------------------------------------------- Botbo1 HRRGS-LVELRARDRTFNGAYARSALGNLGYSVVILKLFDQRFYYIGLLYVILAGFLFLLSILRRRFVTAGWIVVAVSLVLLVL--I Botci1 HRARS-LVEIRAAQRTFEGAYIRTALGQFSFALVVLKIFTAEFYSIGALFATYGAGILMVSLYRRYFRTSGNAVVVLTTLLIGL--T Caeel --------------------------------------------------------------------------------------- Canalb1 NRLPS-KQDIRAHQRTYEGAYTRTAIGCLSFSILIIKLFSKEFLPIGTIYTIYGCLLYFLGVFKSSFTTSGDFVLFLTILLLVL--L Cangl --------------------------------------------------------------------------------------- Capow --------------------------------------------------------------------------------------- Catan2 --------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------- CocheC53 HRARS-LVEIRAAQRTFEGAYVRTAIGQFSFALIVLKIFTAEFYSIGALFAVYGVGILFTSLFRRQFRTSGNIVVALTALLLVL--T Coere1 RRAES-LLEVRARERTFDGAYWRTAVGLFGASLVILRVFGLAFFPVGLVFLALGLGFLGIGLVRRRFCTSGSTVVLSAAMLLVL--L Conco1 ------LLDIRARERTLDGAYWRTSIGLIGASLALIRLFKHKFLNLSIVFICLGVVLLIVDYFRRRFMTSGTFVLITAIALFLV--I Conpu1 HRKQS-MNELRARHRTFDGAYRRTALANLGYALTVLRLFDMRFYKIGILYLVLSAFLFLFEYIRGAFVTAGASVLIVAGLVIVL--I Copci HRRHS-LIELRARQRTFHGAYSRTALGSLGYALTILRLFDSAFHRIGLLFAILGAGLFVLAFLRSRFVTAGWIVIAVAAIMFIL--I Croqu1 HRPAS-RTEWRARQRTHDGAYLRTALLCSTYALMILKLFSREFDKVGLTYAILALVLLVVSFLRRKFRTSGDIVILLSTCLVVL--L CryneH991 --------------------------------------------------------------------------------------- Crypa2 HRARS-LTEIRAAQRTFEGAYMRTALSQFSFALIILKIFTSEFYAIGALFAAYGAAILLVAIFRRYFRTSGNSVTLLTVLLMVL--M Debha1 ERMSS-KLDVRAHQRTYEGAYTRTAIGCLSFSIVIIKLFSKEFLLIGTIYTAYGCLLYFIGVVKSYYKTGGNSVLVLSVILLVL--V Dekbr2 QRKPS-KLDIRAHQRTYQGAYVRTCLGCLSFSLLVMKLFSREFMPLGMVYQIYALVLCLASYLRSRYKTSGNIVLWLTVVLFVL--L Dicdi --------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------- Fomme1 HRADS-LVEIRARQRTFNGAYARTALGNLGYAITVLKLFDRRFYRIGLLYTILAGMLFILSYLRSRFITAGWIVLAVSLVLFAL--I Fusgr1 HRARS-LVEIRAAQRTFEGAYVRTALGQFSFALIILKVFTEEFYAIGALFAVYGVAVMLVAVYRRYFRTSGNIISDMQRLLRYIWDT Galma1 HRRHS-LVEIRARQRTFHGAYSRTALGALGYSLTILRLFDPSFHRIGLLFAILGALLFVLSFVRARFVTAGWSVVQVTVVLLVL--I Ganpr1 --------------------------------------------------------------------------------------- Gloin1 RRLQS-LVEIRARQRTFEGAYWRTCLSSFGFALIILRIFEKDFYGIGLVFVAFGGAMLTISALRRRFVTSGGYVVLTSVILLIM--V Hisca1 --------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------- Lacbi2 HRRQS-LVELRARQRTFHGAYSRTAIGALGYAITILRLFDRDFYRIGLLFAILGALLFILAFFRARFVTAGWIVLQVSAVMLIL--I Lenti61 HRSKH-LVELRARSRTFDGAYSRTAMSNLGYALTILRLFDRRFFRIGILYTVMAGLLFIIAFFRQRFVTAGWIVALLSVVLLVL--I Malgl1 -----ERSRYTAAQRTFDGAYMRTALSQLTFSLTVIKIFQPEFFWIGLMNCVLAVGLIITAVLRHRFQTAGHIVVFVMLIIIYL--L Mellp23 HRPESLMVEWRARQRTFD---------------------------VGLIYALLSLVLLLFIHVRRRFRTAGDVIIILSLILIVI--I Mnele --------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------- Morel2 HRARS-LVEVRARERTFDGAYWRTAMKSFSMGMIIIRLFTKAFYEIGIIFVAFGMTMLGISVLRRKFVTSGFWVAATTAVMFVL--I Mucci2 HRRES-LQDLRAHQRTFEGAYWRTALAAFSSGLLILKVFTREFYKIGITFFVFGLAMLAIALWRRRYKTSGDWVILTTVVLLVL--L Mydma --------------------------------------------------------------------------------------- Neucr2 ---------------------MRTALSQFSFALIILKIFTSEFYPIGALFAVYGAAVMLVAIYRRYFRTSTNSVALLTGLLMVL--L Orpsp11 --------------------------------------------------------------------------------------- Pench1 --------------------------------------------------------------------------------------- Phybl2 HRRES-LQDLRARQRTFEGAYWRTALAAFSTGLLILKVFSREFYKIGITFFVFGMAMLAIALWRRRFKTSGNWVILTTIVMLVL--L Picst3 ERLPS-KLDVRAHQRTYEGAYTRSAIGCLSFSILIIKLFSKEFLPIGTIYTVYGSLLYFIGVYKASFKTSGDSVLLLSVILLVL--I Plicr1 HRAES-LVELRARQRTFHGAYRRTALGNLGYALAVIKLFDARFYRIGLLFALLSAMLFALSFVRARFYTAGWVVIAVTGALFWL--V Polpo --------------------------------------------------------------------------------------- Pucgr2 HRSGS-LTEWRARQRTFDGAYLRSALGCSFFALTITKMFRKELSQIGLEFAALSLLILSISYIRRRYRTPGDFVLLMAAALIIL--L Punst1 HKSKT-LVEIRARQRTFDGAYGRTAIGNLGYSLTILKLFDRRFYR---------TLLFVLSFFRSRFRTAGWIVVAVTGVLLLL--V Rhior3 --------------------------------------------------------MLVIAVWRRRFKTSGDWVVLTTIVLLIL--L Rhoto1 HRRKS-MLELRARARTFDGAYTRAALSNLGYALLVLKIFSHEFARIGLIYAIMSMLLLVIAQYRRRFRTSGDVVVLLGVVLFAL--I Rozal11 --------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------- Salro --------------------------------------------------------------------------------------- Schco3 HRSYS-LVELRARQRTFHGAYSRSALSALGYSLTILRLFDHRFYKIGILFAVFGVLMFFLSFYRSKFVTAGRVVVLVTALLMVL--V Schpo1 --------------------------------------------------------------------------------------- Sorma HRARS-LVEIRAAQRTFEGAYMRTALSQFSFALIILKIFTSEFYPIGALFAVYGAAVMLVAIYRRY--------------------- Sphar --------------------------------------------------------------------------------------- Spipu1 --------------------------------------------------------------------------------------- Sporo1 HRRTS-LIELRARQRTFGGAYERSALGNLGYALLVLKIFNPDFAKIGLLYVILSILLLLIAQYRRRFKTSGNQVLLINLTLMAL--V Stehi1 HRAES-LIEVRARQRTFNGAYSRTALGNLGYSLAILKLFDRRFYRIGLLYAVLAALLFVCSFLRSRFVTAGWIVVAVTGVLVVL--I Tapde11 --------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------- Treme1 --------------------------------------------------------------------------------------- Trire2 HRARS-LVEIRAAQRTFEGAYMRTALGIFSFSLVILKVFTEEFYGIGALFAAFGTAILLVAVYRRYFRTSGDTVVLLTVLLLGL--T Umbra1 HRKQS-LLEMRARQRTFEGAYWRTAIMAVSTGLLILKVFTKEFYKIGITFFVFGLVMLGIAVLRRRFQTSGNWVLLTTIVLLVL--L Ustma22 -----DLLDYRAVQRTFDGAYARTALGQLCYATVILRLFQPKFFYIGLAYAILGMGFIPVAVFRYRFVTAGSIVAAATALILVL--I Walse1 --------------------------------------------------------------------------------------- Zygro1 --------------------------------------------------------------------------------------- [Cluster3792.fasta_al_trimmed; alignment length = 228] Allma1 LLCQRTKVLAHVVLEDTVLFPEGGGQPADRG-VHMVGDEVEATVDWARRWDAMQQHSGQHLLSALAETV-YGWRTASWALGTDRLDVLEDMVADHIAAKTLPQDLTMRTVVIGAVDVSLCCGTSVASTAQLQTVAIKPSIAKIRGNSRVFFAFGE-RVDAALGVS--GADKVSGVMETAKRLVNTLTNELTSLDFLVTLANTFVLTGVPHVGDDVKGGGG-KGLWQGR Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 LACQRTTLVSDVVLHDTVLFPEGGGQPSDIG-VHTVGDSVNVSLGWARRYDHMCMHTSQHLLSTLMEEH-CALATLAWSLTSDEIARVQAALDAVTSLKGIPDDYVKRTICIDGIDRNACCGTHLPDLQGVN-VFILPQTESISRSVRVFFVAG-PRVLSGAAFG--CAARAAQEFDGRRKRIMELEAEIAALALLDEVQKSALSCGVKRVGEGVKGGG--KGRWSGK Batde5 LLCQRTVVISEVVLADTVIFPTGGGQPNDLG-VHILDQVVQVDLDWDRRFDHMQQHSAQHLLSAIAQKE-FDMKTVGWSLGKHVLDALEQQVNAYIRKKKLPSDLVVRCITFDGLDNNTCCGTHVENSADIQ-CCKLLHTERVRGNTRVFFVAG-NRVNRKLTLS--TGERVEGLKKNIKKTNKKQSKEIA--------------ALIAKQ----------------- Botbo1 -----TTITRELEFEDTVLFPEGGGQPCDYG-IHITGQKVILQLDWARRRDHMQQHTGQHLLSALFDQ--FPNDTLGWSLTSAQIEQVQRRANEIIAEETMPVDYVVRYVHLHELDINPCCGTHHHSLAFLNTIFIFPGTQLMSGRHRLTFAVG-DRVLKDAGIG--CAERVEGLIRGKKRREKVLRAEAA-VEFLGEV---ILSSGVKRAGEKLKGGG--KGRWQGK Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 LACQKTKVVSGVELEDTILFPEGGGQPYDKG-IHLVGTQVRLNVDWGRRLDIMQQHTGQHLLSAVFDT--YKLETLSWSMGEDLVVEVQNKVNQLIVDSHIPDDYIIRIVKIGELDANPCCGTHLTSTAQIQSIALL-HQSPIRGHSRLYFICG-GRVLKNVSLS--CSEKIELLSLNYKSTLNNLLKELALPEYLTWVQKEVLLSGAEELQKNLKGGG--KGSFQGK Cangl LKCQRTNVISVLELEDTILFPEGGGQPSDTG-KHYVGSKISLHVDKEKRLDYMQQHTGQHLLSAILDNYYDNADTLSWSMGGDEISEITDKFNEIVSTKKIPDDYVLRTINIGELDKNPCCGTHLTATSQVQSILILDNQSTVRGNSRLYFMCG-KRVISSAKLS--CSSKVVALKENLQKKEQYFISQIASLDLLLAIQKELILCGIQKTVSNLKGGGGKNGKWQGK Capow LACQRTTVATHVTFEDTVLFPEGGGQPHDTG-VHHTGTPAHQTVDWKRRWDHMQQHSAQHLITAVASDQ-FGLKTTSWSLGAEVMQQLEDKVNEIIAERGLPEDVAIRVVSIGGLDVNTCCGTHVKSTAHLQ-TVKLLHTE-ASRGSRLHFVAG-ERTMRTLGFT--CGDRAEGAIKTSKRQVKALLKEAADQDYLLTVASPFLSITVAAAASGKGGGK--KGRFQGK Catan2 LYCQRTIIVSFVTTADTVLFPLGGGQPADRG-IHTIGTQVQLDVDWPRRWDAMQQHSGQHLLSAVAEQL-FGWRTASWAFGSERVRELEDKVAEYIEQKTLPTDLPIRTVHIHTLDANPCCGTHVRSTAQLGTVLLRPAIERVRGNARVYFTFGSARVEIKLGLS--CGDKITKLVDVGKK----------DMDLLLAMATAYTLSG---VGQGMRGGGG-KGVWQGR Cioin FKCQASKVVAEVELEDTILFPEGGGQPDDRG-LHFVGDTVSMEVDWKRRFDHMQQHSGQHLITAIADTM-FGFKTTSWDLGKDQLFQIECCANKSIRERGLPDDHDVRIVEMKGIDTNMCCGTHVSNLSHLQ-CIKLLSAEKGKKKTNLCFLTG-DRIEKELTLK--CGEAVERSMKQLRKNCTTLLRDVANVEFMNIISNEFLTVGIKECGTGKGQMK--EFKMQGK CocheC53 LQCQKTQVVSLIELADSVLFPEGGGQHTDHG-IHFSGTSVRQTVDFDRRWDLMQQHTGQHLLSAVMDG--MDLPTLGWSMGQEEMQTIQKDCNARIREDSLPEDYVVRFIKIGDMDYNACCGTHLQNSSHINLILLH-HTQSVRGNCRLFFTAG-DRALRSIALSSGSAAGVQRIADQVSKKEKKLLAEIAGLDFINLVLSEVLSTGVEKMAATVKGGG--KGKWQGK Coere1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 LACQRTNIVSEVILHDTVLFPEGGGQPSDVG-VHYVGSHVKVELGYERRYDHMTMHTSQHLLSAVLETK-LNLPTLSWSLTTEEIFAVQNEANKLVFEKALPEDYVKRVVVIHGVDRNPCCGTHLPSLHNLQ-LFLLPQTESVARTARLYFFAG-PRLITSIALS--CGARVVQVTDERRKRAEDVEIELAALGFLNSIAFSVLSSSVKAVGEGVKGGG--KGRWSGK Copci LACQRTSVVQELVLHDTVIFPEGGGQPTDTG-VHYVGTTVTVTLDYNKRYDHMSMHTSQHLLSALLETR-LNLPTLSWSLTSDEILAVQNEANRLVFEKGLPDDYVKRIVVIEGVDRNPCCGTHLPSIHNLQ-LFLLPHTEALSRSARLYFLAG-PRLLTQSALS--CGERLGQVIDDRKKRVGELEIELAPLGFLSSIATSVLTSSVKSTGDGVKGGG--KGKWSGK Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 LACQRTKVHAEVELLDTVIFPEGGGQPSDTG-VHLIGREVEIEADWDRRMDQMSIHTSQHLLSAILDAH-LSLPTLSWSMQPDEAVEIERLCGEAIKQRGLPMDYVIRYINIQDTDRNACCGTQSPNTSLLSPLHVIPPAL--SNPTKLYFLSG-PRALSAAAVG--YGERLERAEVARKDSLKGLRAELADFDWLGLVGATILTSSAKYVNERVKGGGA-RGRYMSK Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 LACQKTVVISAVELADTILFPEGGGQPFDTG-LHIVGTKVTLQVDWDRRIDLMQQHTGQHLLSAVLDT--YDLETLSWSLNEEIVEEINKKVNDYILESHIPDDYIIRIVKIGELDSNPCCGTHLSSTSQIQAISLL-HQVNVRGNSRLHFICG-SRVLKAVSLS--CQEKVGVLNLNYKSRESNLLKELASPEYITAFQKELLINGATEIQVGLKGGG--KGSFQGK Dekbr2 LACQRTTVISEVEFQDTILFPEGGGQPSDTG-VHITGAKVGMQVDWKRRFDHMQQHTGQHLLSAVLDK--RNLPTLSWNMGEQELCDVSDEVNALITQTKMPKDYVLRVVHIGNIDSNPCCGTHLSSTSQIKAVVLL-SEARGKGNFRLNFVCG-DRLIRSLVMT--CQDKVRDLVKDHKTRETSLMKEIADLSYIFRIFKSALITGVDPVVASVRGGG--K-KFQGK Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel FKCQETKIVSNVICEDTILFPEGGGQPCDYG-VHFVDAEVLLTLDYQRRLDHMQQHSGQHLITALFDRE-F-----------ESLDLIERQANDLIRERGLPKDHLARVVRIEGIESNMCCGTHVTNLSQLQ-CIKLLYAE-KVKNVLVHFVVG-ERVEQQLTLK--GGELVQKLQQNVKKYFQQLLKRYAEVDFINTFLRAFLTVSVGKLGPGKGNGK--EDNFQGK Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba AICAQ---------------------------VHYLGMTVEVALDWEHRWDVMQQHSGQHLFSATALAT-FGWRTYRWD---DVLAQLERAVNAAIGRTSKQSLFPVRIIEIDTADSCTCCGTHVSNTSELQLFKILPTVTTRRRTTTISFLAG-GRIDQAVGLS--CSQMIEYNKTRLNALSSSLLSHTCPIEQLKTIVLKAVSCPLATAASAAGGGG--RGCCQGT Fomme1 LACQRSTVVSEVILHDTVLFPVGGGQPSDIG-VHFVGAQVTAALGFSRRLDHMCMHTSQHLLSALLESE-LKLPTLSWALTSEEVARIQARAHALAYEKALPSDYVKRTIIIDGVDRNPCCGTHLPSLHNLQ-LFLLPQTESLARTSRLFFLCG-PRLLTETAMS--CGARVSQVIEERRRRAEELEFELAALGFLQSIATSVSTSTTKTAGDGVKGGG--RGRWSGK Fusgr1 ---------------------------------------------------MMKNH---------------ELKTLGWGMGTEEMQAIQMECAEKIREHKLPGDY--------------CCGTHLAQTSHISLIILG-STQSVHGNCRLSFIAG-DRGINTIAMSVSSNTRATALSDSVTRSERKLLLEVASTDFINKIVGEVIAIGVDAMAKDIKGGG--TGKWQGK Galma1 LACQRTTVVSHVLLHDTVIFPEGGGQPTDTG-VHYVGAKVTVSLGYERRYDHMSMHTSQHLLSALLETR-LDLPTLSWSLTSDEITSVQAEANRLVFEKALPEDYVKRVVVIDGVDRNP------------------------------------------------------------------------------------------------------------- Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Gloin1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 LACQRTTVIAEIELQDTILFPEGGGQPSDSG-VHITGAKVSVEIDWDKRLDYMQQHTGQHLVSAILEQK-WGLKTLSWSMGGEEVKELSDTVTEYITVHKVPDDYVLRVVHIEDLDKNPCCGTHLQTTSQISSVLILPSQSSVRGNSRLFFMCG-DRVISNTKLS--CSHKCDMLLKNMQKREQFWIKELATLEFLTQLYNEYVLAGIQEVSDQLKGGGGKNGKWQGK Lacbi2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lenti61 LACQRTTAVSEVILHDTIIFPEGGGQPSDVG-VHYVGALVGVSLGSKRRLDHASMHTSQHLLSAVLENK-LDIPTLAWSITTDEIAFVQDECNKLVFE--IPQDYVKRTVIIDGIDRNPCCGTHAPTIHNLQ-LFLFPHTETLSRSVRLYFLSG-PRMLTATAMS--CGERVQQVVDERKKRVEDLEAELAALGFLSAITTAVLSSSVKEVGDNVKGGG--KGRWSGK Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mnele LKCQKSRVISEVVLEDTIMFAEGGGQPCDHG-VHYTGSEVNMEVDWKRRYDHMQQHTGQHLLSAIAEQEPYNFKTVSWNLGAEVKSEIEQKINSLIQSRGLPADHPVRVIEIEGVDENMCCGTHLNSLAQLQ-MIKLLHTE-SKRNTLLYFVCG-DRVQQKLNLS--SPSMVEKLSKDHRKNAEKLSEELADSEYSLTLQRDLLTMGVDKLGKGKGGGR--DGKFQGK Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 LTCQHTTVLSEVQLQDTILFPEGGGQPCDYG-VHHTGIEARLEVDWKRRFDHMQQHSGQHLVSALFEQPEYGCDTLAWGMNAEQVQEVEDRLNLYIRRATLPKDYVFRVIEIMQLDYNPCCGTHVKSLKDLQ-CIKLLHQEKIRGNSRLYFVVG-QRATKDLALSAPGGDTIVKNQKAARKQVKNLLKEIADMDFLGVITALMLSAGVKKIATDIKGGG--KGRWQGK Mucci2 LHCQNTECISQVELVDTILFPEGGGQPCDTG-VHYTG-PVSLRLDWDRRWDHMQQHSGQHLLSAVLEQAPYNIETISWSLGEELLKEVEIIVNQLIVKDSLPKDYHIRTVEIQDLDRNPCCGTHILALGQLQ-CLKLLHTENVRGNTRVFFLFG-QRVTRQITLS--GGDNIQKLQQQNKKRAKRYLEQLADMEFLGMVANVILAAGVQKTGKGVKGGG--KGRWQGK Mydma FACQRVKVVSEVILDDTPLFPEGGGQPCDEG-VHLTGEEINCKINWSKRFDHMQQHSAQHLLSAIAENK-YNFRTVSWDLGKEQLTHLELICNEAIRNRGLPEDVPIRVIEIEGIEKNMCCGTHVSNLAHVQ-AIKLMHTE-AMRGTRLFFLAG-DRCERKLTLS--CGDSIDKLKSSLRKSFRNNLKELADTDYIFAVLNSFICTGLTTLAEGKGGAK--KGQFQGK Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 LHCQKTKCISEVKLHDTVIFPEGGGQPSDTG-IHFTNKEVEVTLDWNRRWDHVQQHSGQHLLSAVLEKEPYNMETLSWNLGPEQLATLESRVNDLILEDSLPADYSIRTITIEGLDTNPCCGTHVRHLGHLQ-VLKLLHVESARGNIKLFFLFG-QRVSRQVTLS--VPENITKLQQQTRKQIKRLMTELADMDFLVDIASAVLAAGVQKTAKDLKGGG--KARWQGK Picst3 LACQRTQVVSAVELEDTILFPEGGGQPYDKG-LHITGTEVTVDLDWDRRIDLMQQHTGQHLLSAVFDT--YKLETLSWSMGEEIVAEVNAKVNKLIFESHIPDDYIIRIVKIGQLDANPCCGTHLSSTSQIQSMSLL-HQVSVRGHSRLYFICG-TRVLKLVSLS--CQDKVALLNSNYRSREQNLLKELASPEFLILVQKEVLFNGAEVLQSNLKGGG--KGSFQGK Plicr1 LACQRTTVVSEVITHDTVIFPEGGGQPSDIG-VHYVGAKVTVALGFTRRQDHMTMHTGQHMLSALLHQH-FKLPTLSWSLTATEIAIIQDEANKLVFEGALPVDYVNRIVIIDRLDRTPCCGTQLPTLHNLQ-VFIVPHTDS---SGRLYFYAG-PRLLTAAALN--VNERVLSITDERRKRVDDLEAEVATLPFLTAVSNAVLSSSVKAVGEGVKGGG--KGKWSGK Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 LACQRTTIVSELVLHDTVLFPEGGGQPSDVG-VNYVGSMVTVALGYNRRLDHMCMHTSQHLLSALLETR-LNLSTLSWSLTAEEIAAIQQEANKLVFEKALPDDYVKRTVVIDGVDRNPCCGTHMPSLHNLQ-LFLVPHTEALSRSARLYFMAG-PRLLASAALS--CGQRCAQVLEERRKRVQELETELAALAFLSGISMAVLSSSVKEVGESVRGGG--KGRWSGK Rhior3 LFCQKTQCIDEVMLYDTVLFPEGGGQPCDTG-VHYTGKTVHVQIDWDRRWDHVQQHSGQHLLSAVMEKEPYGLETVSWNLGKELLSKVEKAVNELILQETLPDDYYIRTVEIKDIDRNTCCGTHIKRLGQLQ-TMKILHTENVRGNTRVFFLFG-QRVTRKLTLS--GPENVQKIQQQSRKKAKRLLESLADMEFLSMIANIILAAGVQKVGKRVKGGG--KGRWQGK Rhoto1 LACQRTTVTREVELLDTVLFPEGGGQNSDSG-VHYVGTKVRVEVDMERRRDLMDQHTGQHLLSAVFEQD-LKLDTLSWSLQKDEITYVQKRCNDLIGEEKVPEDYVQRTVIIDELDENPCCGTHYPSLAYLRTLYISPNTTSIRGNARVYFAVGAPRLAREAAAG--CATKVEGLVNGVSRNQKRLAGELASLEFLSSISLEVLASGVMQAGKRIKGGG--KGRWQGK Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 LACQRTLVVSEIELQDTILFPEGGGQPSDSG-KHHVGTTVEVAVDEQKRMDYMQQHTGQHLLSAILERN-YKVDTVSWSMGGDEITNVSDEINQLIINSKIPDDYVLRTIHIGDIDSNPCCGTHLKCTSQIGSILILSNQSAVRGNSRLYFMCG-KRVLLDSKLS--CSEKITRQTKQIQKREQYWIKRLATLELLLQIHKEIILCGIANLAANLKGGGGKKGKWQGK Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 LACQRTVVVSGVLLHDTVIFPEGGGQPTDTG-IHYVGTPVKVSFDWERRYDHMTLHTSQHLLSALLETR-LQLPTLSWSLTSEEIASIQNEANRLVFERGLPSDYVHRVIVIDGVDRNPCCGTHLPSLHNLQ-LFLLPHTDALSR--RLYFLAG-PRLLTAAALT--CGARVALVVEDRKKRVTDVEGELAALAFLTSIAAAVLSSTVQGVGAGVKGGG--RGKWTGK Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sporo1 LACQRATVLREIELDDTVLFPEGGGQPSDTG-VHLVGSQVLARVDMDRRTDLMSLHTAQHLLSAVFERD-YGLDTVSWSLQKEEIEKVQARCNQAIQEEKAPQDYVQRTVIIDGIDENPCCGTHYPDMSWLRSLFISPFTTPIRGNCRLYFVAG-PRVARTSAAG--CNDRVNGMVSSLARKEKRMKEEIASLDFLSLVSIDILATGVVKAGKKIKGGG--KGRWQGK Stehi1 LSCQRTTVISQVVLHDTVLFPEGGGQPSDVG-VHYVGRKVSVELGFKRRLDHMSMHTSQHLLSAVLESH-LSLPTLAWSLTSEETTLIQDECNRYVFERGLPSDYVHRVVVIDGVDRNPCCGTHLPTLSSLQ-LYLLPPPAG---PVRHYFLSG-PRLLTRTALS--CGERVALVAEESKKRMDDVEKELAALSFLQAITFALLTSSVKEVGETLKGGG--KGRWSGK Tapde11 LACQHTTVCDEVQFLDTILFPEGGGQPWDHG-IHYVGTQVELKLDFDRRFDQAQQHSGQHLLSAVLDT--LDIPTLAWSMGPEDLKAVERQCNKHIADKNLPADYVIRVVSIGGIDANPCCGTHVRSTAELNSLTIL-YTNPIKGNHRIYFVVG-GRCARTMGLS--CQEKITVMQNQLKKREKNLKSDLVDIEYLNALLAAVLVAGVKELSAAMKGGG--RPKFQGK Thetr ----------DVVLDKTVVFPEGGGQPADTGVVHHRGESVVVKVAEARRIDHMQQHSAQHLVSAVAAEV-FGAATVSWELGSVDVAALEARINALIRARGLPDSV-IRLVAIAGVDLNTCCGTHVTNLSELQAIKLLPPSRSKKHKMQLSYVAG-QRVSSQLN----LGECIASYKSAAKRTQKALVAQLADAAFAKSAAARFVTCGVDAVGK--RGGG--KGKFQGK Treme1 LACQRTKVISEVQTEDTVIFPEGGGQPCDLG-VHLVGLEVDLEVDWVRRQDQMAIHTAQHLLSAVLDT--MELPTLSWGMPAAEVAEVEQKCNALIRERDIPKDYVIRHCNIEGTDRNACCGTQCPSLKHCEMIHLIPPSTPSTSPTRLFFTAG-PRALSLASIS--VNARVEKIDELRRTQLTAVRSELQHFDFLSGVTGTVATSAAKEVFDRVKGGGA-KGRFMAK Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 LACQKTKCIGEVLLHDTILFPEGGGQPNDTG-IHFTDKEVTLKVDWDRRFDHVQQHTGQHLLSAVLEQDPYKFETVGWNLGDEQISQAEDAINTLIFSDSLPSDYVIRTIEIEGLDRNPCCGTHANNLAQLQ-SIKFLHTEKIRGNMRLYFVVG-RRVCKSLTLS--CGPQITRLQTLQRKTIKRLMAELADMDYLVLLANGILAGGVKKATQGLKGGG--KGRWQGK Ustma22 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Zygro1 LACQRTTVISLVELHDTILFPEGGGQPSDSG-KHHVGTTVEVEVDQSKRVDYMQQHTGQHLLSAILESEPYKLDTLSWSMGGQEIEQVSHKVNELISISKIPDDYVLRTIHIGEIDSNPCCGTHLQRTNQIGSILISPNQTNIRGNSRLYFMCG-NRVVGTAKLS--CLEKIDRQRDLIQKREQFWIKELATLEFLLQVFKELVLCGISTIAATLKGGGGKKGKWQGK [Cluster3793.fasta_al_trimmed; alignment length = 132] Allma1 ------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 NWEQWHMHEHQMAEYTPEKFFNLHDTNGKGYMDERDILSLYGLEETANRIVKLIGELLDTNDDGKVTKAEYLNKSFPDLGEKEFNVHHWNTHH--QNNE---KTTHREDVEHDLLHYYHSLEQDEKQKIPSK Aspfu1 DWATRHMEEHHIDSFDAGSFFTLHDYDSSGAWTPDEVRKTYGMEERKQQALREVFALFDTGSSGVITRDNWMRKRLPDLGEYEYEIHHFERFH--GEDAKLEDLTHPEDIEHFRRHDEEEDATDREANIPQK Aurde31 GYIKAHMNEHHIDTFDLRSFFLIHDLDRDGFWDRGEIEAVYGVKEKADQVVARVLKLLDKDGDNRISSAEFEAPNLKDLGESEFFLHHEELYHSSPDTQTDEAYNHPEDDEHFANHEHIEAEEERRRNVPYK Batde5 ------------------------------------------------------------------------------------------------------------------------------------ Botbo1 EYAVRHMSEHHINAFDLKSFFTLHDLDNNGLLDAPEIEAIYGVAQKAKDIVAAVLERIDSNRDGVISPEEFEAPDFSKWGESEFFLHHEELYHSTPETQTDESYNHPEDIEHFAQHEAIEREEENRRNVPYK Botci1 DWGTRHMEEHHIENFDAGAFFTLHDFDNNGVWDQAEILKFYGMQEKKDNLLKEILKLMDNNNNGQVEREEWDRALLPDFGEMEYEIHHWQKYH--DENTKEEDLIHPEDIEHFKKHDELEDEADREQNIPDK Caeel ------------------------------------------------------------------------------------------------------------------------------------ Canalb1 SWQDWHMEEHGLEEYDGKTFFILHDLNNNGILESKEILNLYGLPELQKQVVENIFQLIPHGNPEGISQAEWLKGRLPDLGEEEYEEHHWRKYH--ANDDPDVKIKHKEDIEHELLHHQQEIEETHIDNLKPK Cangl SWEEWHMHEHELKKYTPEQFFALHDVKKKGYWDENDILGLYGLETTAKNVVKFIMKLLDVNDDTRILRDEYLEKKLPDLGEREYEIHHWNKYH--KDKDVNVKNVHKEDIEHELLHHEHDIEHQELKNIPSR Capow ------------------------------------------------------------------------------------------------------------------------------------ Catan2 ------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------------------ CocheC53 DWATRHMEEHHIAGFDAEFFFRLHDYDNTGLWAAMDIRRTYGLDAKKQLVVQTILDMFDINKDGVITLEEFAKTKLPDFGEYEYEIHHWEKYHS-GDDVKEEDLNHPEDIAHFKMHEEKEARQEEEKNIPEK Coere1 ------------------------------------------------------------------------------------------------------------------------------------ Conco1 ------------------------------------------------------------------------------------------------------------------------------------ Conpu1 ------------------------------------------------------------------------------------------------------------------------------------ Copci QYAQRHMKEHHIDTFDIRSFFHLHDLNRDGFWDREEIEAVYGVQKKADHIVNTVLGILDLNKDGKVSPKELEKPNFEHMGESEFFLHHEEEFHSTPETQTDEAYNHPEDLEHFAHHEKIEKAELERKNLPYK Croqu1 DFLSAHMSEHHIQGFDMASAFHLHDLNRDNILEAEEILKLYGVDSKAERILREVMNRLDVNKDGIITKTEFVSPQFPDIPEGEYFLHHEETFHSTPETQTEESYQHEEDLRHFAHHEEIEAKEDERKNVPYK CryneH991 SYAERHMTEHHIDSFDLESFFKLHDLDMNGYWDELEIQAVYGLDGRAQNIVAQVLDALDKDQDGKISLDEFLAPSFEGYKESEYFLHHEELYHSTPETQTEESYTHPEDIEHFQHHAEIEDEEDARAGVPYK Crypa2 DWMTKHMEEHHIADFDASSFFALHDFDSDGQWEGSEIQRTYGLDERKQEIVREVLRLADADGDGVIRRDEFENGTLPDFGEFEYEIHHWEMYH--DENTKLEDLTHPEDIEHFRLHDQMEDEQDREENIPDK Debha1 SWQNWHMEEHQMDQYDTDLFFKIHDLQNKGTWSRDDILNLYGLQEAKDHVVNSILELIDSDGDRQISLNEWRQGELPDFGETEYEEHHWNKYH--ANQDPEVLIKHREDIEHELLHHEHEIEESHIQNVPSK Dekbr2 SWQRWHMVEHDLDDADPEAVFKLHDTRNANRLCAYDILRMYGLRQLKEKVVNKVMDLIDTNNDGEISLDEWKRGEFPDFGEDEYEKHHWIKYH--SQNDPDVNVQHAEDVEHELLHHFHEIEHEQLDHVPAK Dicdi ------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------ Fomme1 EYAQRHMKEHHIDTFDPESFFHIHDLNRNGVLDKDEIEAIYGVQAKADHIVNTVLGIYDKNNDGKISVEEFMEPNFEGLGES-------EEFHSTPDTQTDESYNHPEDIEHFAAHEDIERQEAIRKNVPYK Fusgr1 DWMTKHMEEHHVQGWDADSFFTLHDYNGDGWWQAAELMRTYGLDKRKEEVRDILLGLLDKDSDSSVSRKEWMDKTLPDLNEYEYEIHHWEKYH--DDNTKLEDLTHPEDIEHFKKHDEMEDAQDREANIPQK Galma1 QYAQRHMSEHHSDSFDVRSFFQLHDLNRNGYWEKDEIEAIYGVQMKAEHIVTAVLQRLDLNGDGLITAEELEQPNFDGLGESEFFLHHEEQFHSTPETQTDESYTHPEDMEHFAQHESIERKEAERKNLPYK Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------ Gloin1 ------------------------------------------------------------------------------------------------------------------------------------ Hisca1 DWATRHMEEHHISNFDPGSFFLLHDYDNSGVWTVEEVRRTYGLEERKQQILKEIFSIFDPQKTGVISQHEWMRKKLPDFGEYEYEIHHFEKYH--GDGATEEDLTHPEDIEHFRQHDHAEDAQIREANIPVK Klula1 SWEEWHMDEHGITKYTPEEFFDIHDLGSKGYLDATDIITMYGLDSLREGAVKIVMALLDVDDDTRITRKEYLANKLADLGETEYEMHHWNQYH--KDQDPDIKNVHKEDVEHELLHHEHEVEAAEQDRIPKK Lacbi2 QYAQRHMSEHHIDSFDIGSFFQLHDLDRNGFWDRDEIEAIYGVQKKADMIVSTVLGLLDLDKDGKVSPEELAKPNFDDVGESEFFLHHEEKFHSTPETQTDDSYTHPEDLEHFAHHEDIERKEAERKNLPYK Lenti61 QYAARHMSEHHIDSFDVPSFFQLHDLNRDKRWDKEEIEAIYGVQKKADYVVSEVLKRLDKNGDGTITLDELEAPSFDELGESEFFLHHEEQFHSTPETQTDESYNHPEDLEHFAHHENIERIEAERKNLPYK Malgl1 NYMQDHMSEHHIGAFDLASFFALHDLDRNGILERAEIEAIYGVDGKADMIVREVLRRLDTNKDGVVSRAEFLRPQFPEFGESEYFVHHESLYHKTPDEQTEEAYSHPEDIQHFNQHAQIEREEEQRAGMPYK Mellp23 DFLSAHMSEHHIQGFDMASAFHLHDLNRDNILEAEEILKLYGVDSKAERILSEVMEKLDINKDGIITKSEFVAPSFSDIPEGEYFLHHEESHHGTPETQTEESYAHPEDIKHFSHHQEIEAKEEERKNVPYK Mnele ------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------ Morel2 ------------------------------------------------------------------------------------------------------------------------------------ Mucci2 SNQVRHMEAHQIEVTDEVTFFKLHDVDGDGFWDEKELQSMYGLTSHIKKIIDRVYEEMDMNKDRFISMDEYIT-KLPSITEEKLEKEYRKKAPPPPPPAKNSK----RDATSGK-KAE-------EGVIPNK Mydma ------------------------------------------------------------------------------------------------------------------------------------ Neucr2 SWMVKHMEEHHVENFDAASFFALHDFDADGTWEGLEILRTYGLQPRRDEIVRDILGLIDYDRNGVITKDEFVRKTLPDMGEYEYEIHHWEKYH--DDNTKLEDLTHPEDIEHFKKHEEMELEEEREENIPAK Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------ Pench1 DWATRHMEEHHIASFDPTSFFILHDYDSSGTWTPEEIRKTYGLEENKQDAVRAVFELFDAGNTGFIDREDWLAKRLPDLGEYEYEIHHFEQYH--GDDTTEADLTHPEDIEHFRKHDEQEDAAIAAGNIPQK Phybl2 TFEEEHLDTHQIQSADEMSFFKIHDLNGDGFWDAHELRAMYGLAKHIRTIIDRVFEDLDKDLDGYVSMAEYMT-KLPNWTEEKVADKMWKEEHPYQSTNENEQ----NDASQHVFKAEIEDD---EGHIPDK Picst3 ------------------------------------------------------------------------------------------------------------------------------------ Plicr1 QYAQRHMSEHHIDAFDARSFFHLHDLNRDGFWDREEIEAIYGVQKKADFIVKAVLDKMDTSNDGKITPEEFEAPNFDDMGESEFFLHHEEEFHSTPETQTDESYNHPEDIEHFGHHEAIERKEAERKNLPYK Polpo ------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 DFLTVHMKEHHIQGFDLESAFHLHDLNSDNILEASEILKLYGVNSVASRILSEVMEKLDLNQDGLITKSEFVSPKFDDISEGEYFLHHEEMFHNSPDSQKEEAYIHPEDIEHFTHHEEIEVKEDERKNIPYK Punst1 QYAQRHMTEHHIDTFDLGSFFHLHDLNRDGFWDKEEIEAIYGVQRKADHIVNTVLAAVDKDKDGKISREEFEKPNFEELGESEFFLHHEEIYHNTPETQTDESYTHPEDLEHFAHHEEIERKEAERKNLPYK Rhior3 ------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 TYAELHMQEHHMDSFDIQAFFHLHDLNRDGVLDRNELESIYGVTQQAKDIVEAVLAKLDTNQDGVLTMREFVAPNFKGVEEGEYFLHHEEKYHNTPETQREEDYVHPEDIEHFLSHEEIEEQEDERRNVPYK Rozal11 ------------------------------------------------------------------------------------------------------------------------------------ Sacce1 SWEEWHMHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNEMAKRVVSLIMRLLDVDDNTKITKEEYLQNKFPDLGELEYEIHHWNKFH--KDKDPDVKVVHKEDIEHELLHHEHEIEHEELKNIPEK Salro AHATKAV------DFDRDALFAEYDQDGDGYLNAHELDTMYENEFDHSATFDMIWSQLDADGDKLISKDEYFASMVDVAG------------------------VRLDDVDSGSHHK--------------- Schco3 EYAQRHMKEHHIDSFDLPSFFQLHDLDGDGVWNRGEIEAIYGVQKKADTIVETVLAKMDKNKDGEIALEEFVLPNFDNLGESEFFLHHEEEFHSTPETQTDESYVHAEDIEHFRHHEEIERKEAERKNLPYK Schpo1 GWMDTHMDEHHIDKYTDESFFRLHDLGKKGYWSDQDILSLYGLFVKKNEVLVDVLKKCDPSGNRRITLDEFLAGELTDFGEEEFEMHHVEKYHPAGLDEPDENWNHPEDIEHFQKHDEIFHGDKKYNNIPDK Sorma PWMVKHMEEHHIENFDAASFFALHDFDGDSTWEGLEILRTYGLQPRRDEIVRDILNLMDYDNNGVITKDEFVRKTLPDMGEYEYEIHHWEKYH--DDNTKLEDLTHPEDIEHFKKHEEMELEEEREENIPAK Sphar ------------------------------------------------------------------------------------------------------------------------------------ Spipu1 ------------------------------------------------------------------------------------------------------------------------------------ Sporo1 --------------------------------------------------------------------------------------SHEEQFHNTPETQREEDYIHPEDIEHFMSHEQIEAEEEERKNIPYK Stehi1 QYAQRHMTEHHIDSFDLASFFQLHDLNRDGVWDKEEVEAIYGVKAKAKVIVDTIMNALDKNKDEVVTMEEFESPNFDNMGESEFFLHHEEEYHSTPETQTDEAYNHPEDIEHFASHEKIEIQEAERKNLPYK Tapde11 ------MNEHHLTMFDDDAFFRIHDLDRTGFWTKDDVTSIYGVPAKVQEIENTIMNLIDKDRSGQISRDEWIQGELPDFGETEFDIHHVEIYHSDPDDDDESKWNHPEDIEHFRKHDEKYHGKEN--NIPVS Thetr ------------------------------------------------------------------------------------------------------------------------------------ Treme1 SYAERHMTEHHIDSFDLPSFFKLHDLDSDGYWDQKEIAAVYGLKAKVEEIVNVVLQRLDTDRNGKISLVEYIAPNFPGYKESEYFLHHEELYHSTPETQTDESYVHQEDIEHFQHHIHIEAEEDA----PYK Trire2 NWMTKHMEEHHVDGWDAASFFTLHDYDSDGYWKGDELLRTYGLWERRDEILRGLLDLLDFNRDGLVSRDEWTAKTLPDMNEYEYEIHHWEKYH--DENSKLEDLNHPEDIEHFKKHEEMEDEQEREENIPKK Umbra1 ------------------------------------------------------------------------------------------------------------------------------------ Ustma22 SYIQRHMTEHHINAFNLGSAFALHDLDRNGVLDRSEIEAIYGVDQKADKIVRAVLLAMDTNGDDLITRKEFIDPLFPEFKESEFFVHHEELYHNTPETQTVEAYNHKEDIEHFSHHEEIEKEEEQRKGAPYK Walse1 NYIAQHMSEHHINGFDLVSFFKLHDLDRDDLLTGPEIEAIYGLSKKVEYVITEVLKSLDDNGDGVITLREFKNPSFPELGESEYFIHHEEKYHSTPETQTDESYNHPEDIKHFANHGHIDHDEDSRKNLPYK Zygro1 SWEKWHMHEHKLDDYTPEHFFDLHDEGGKGYLNRGDILALYGMQELGDRVAQFIMKLLDVDDDSKITKQEYLNGVFPDLGELEYEIHHWNEFH--KDKDPDVDVIHKEDIEHELLHHEHEVEHEEPDVIPKK [Cluster3800.fasta_al_trimmed; alignment length = 448] Allma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 DLANEIATR--KKSAM-ERGIKLTVVLTFIRRQSALDSRAALFVRSLQDALYDSAMEYYSAHNKRVRRKRN--RVRYDYKLATFAE-FRAEEEVARKHYEDCWIQLVDMAEAKVLADCISLKICKLYLYHGEALAHVNRHVQRFAEMFEY-WSWLARQQRCLAETQTRYERFVNEKKVHQALVLELYTKAYDFKKFNRLTLYIAYHIALSYHT-AGKFDMAV-RFFERIAKTYRREQWGKLLQPILYASARQMEPAVRLLFEMLASEQDGGSAPLGDWTTLFWSAAFQLHLFFGDHADLRRLVVSGAVKAVLCLHYVTTHQSPAYLDEAYPIVINVANDDLAVTVDVLGPGESVSKGDRVLDISVQVPPLECAWSVGPWAIELQSVELGDGYSMRLTWRRAFVEPPAVPFTLRLVIQNTADLALQLFVLSGLRLLIAGAQEELELRLP Batde5 ILANEINEK--RKQIH-EAGLKFAIILSYIRRASMID-RQHQFVEGLQRGLLEITSVYYREHEKRIKRKRA--KVRYDFKLGFFAE-CRQDLEAAIRHYDTAYTGIINITEARIFADSLSIKMFKLLLYCGHALVQLHKHFVHCRGSFQY-WAWASTQYRAFGEAEERWNKLDLENATHTMNIIELLTKGYEFKKYKRMTLYLASDIARVYEE-GKKYDMAL-KFFDRIGKTYRKEGWFTILASINIKCALQLAVALESIVELLSLVSDRQAISFLQCNVQLKTINYQLVVKFSNYAPINSKIFEGVISVSIILELSCIFVSPGYIDELVPITIRLTNQEMHLFISCVEPNATIDSGPRVLVTTLYECPFETSSELGKWEIEVEHAELGHSQGLALKWRRINATIPGTPFELRYTIQNLAELLSYMFVFAGYKKLLPLSTQTLRCALP Botbo1 TMSNEIAGR--KKTLS-ERGIKLTVVLSYIRRQSGLDSRAALFVKSLQDALYEPSMEYYNNHSKRVRRKRN--RVRYEYKMATFAE-FRSELEVARKHYEDCWLGLVDMAEAKVLADCVAIKICKLYLYHDEALAQFNRHLQKFGETFEF-WGWMARQYRILAETQQRRSRFINEKKVHYAMILDFYTNAYEFKKYARMILYVAYRIAETYHA-SGQLELAVSRFFERIAHTHRREKWGSMLQPLLYDCAKRLDLSIKLMIEILASLEERASIPIFDSTVVFWQASFQLTIHFSDQANLRAKVFAGTLNVVLTIHASSVHDSPAYVNERYPVIIEISNVDLQIHVDAVSSGDAILKGERVIDISIQSRPLDTTFDIGPSDVELISVRLGDAYLIEVMWRRALVRPPPTPFALALVIKNTADVVLQLFVVSGPRALLPGAADVIRQRLP Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ECAAVFDKL--RQSTA-GRATRHVLVSNSMRRACQIP-----LVAKLEKALIDMAYAYYRDEAKRLKQRKE--RARLFFKLAYFAE-MRSDGKAAIKYYGSSYAYLKELAEVKAVAGLINYKLCRLHFMFN-ALDQFRKHVANYRLAFEH-SAWLGRQYRVFAEMDEKAHAKLAELLVHSGLIITLLSMAREFKKMRRMTLHMAVHIAQEYCQ-AGEHERAL-KLFERIAVDYRKERWWPVLESVLLACAYLIQDFVVLSLELIAKHAPQRSIPFIECKVIFAAVVMHLALKFNVAADLTPKLFRLQFEASIVIERPSTHTPPALVNEFYPVKLVFTSREYNVSVHLMEPEASQEQGEQILTVKMSVLPFTLLVKLTPWPISIVKTELGDTMSYKIHWLRIVPQIPASPLEVSYAIVNTQEIELVMFMFSGLKRVLPSASTSVRLPLP Catan2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 QTAEDMARN--RVCLA-AFGLTYTAVVAALAQRAGLDGTQ-MAAAELERQLFRRAAAYYTDAFMRTQRRVA--EVRYHFKLALFAE-CAGDRDTAQRYLPAGHDAVADGDEAVVLLEAVHLRIVRGWLYQSLAARQCAEHVLLLAHSCSYFWACVARQFEAHAATSSRSGMAAQEIAALSSLDI----LISD---KRRLCLYLTSVLAEIYAE-CGKHQKAL-DIFGQLVKRFRHEGWPLLTAHTLTVCAVAVPASVRALIELLSDMDQRYLISPILCHAHWRHMPFQLTLELRPRLQLRTRGTSDSIMAISRMPLLPTALAPAYCGESFPVEIRVENMHSRIELDIASSSVAVVRGEWTGQTSVKVKPLSTGEGAGPWDVVIGRVVLGSAQQLEIEWRRS------EPLAVCYRLLNTQAIEATMFVFAGPRNIMPGHVALLQRHVP Conco1 ALAQTISDY--RKLMN-ERGIKLIAVLLHIRRTSGLDPKTGFFIHGIQKSMAESCMNYYRERYKIVKKKYT--RARYEFKLGTFAA-FRQDFELAVKHYESCYFSLIEMKETLDFMDCLSLNINRLMLYLESSLIQLKRHLFYGKPEHEY-SKWEFSQYFAFAEQTHQKKS--KEQEVETTQIIEVLSKSYEFKKYRRMTLLVASKIAETYLN-SEKYDLAS-KFYERIAKSYRKESWPQLLQMILLKCAQYLEWFLLNSFELLSEGQHHSIVSFIYFSATFEPIKLQLQVSFKDPSNLETKVLETTISIHGSIATHSIPPTQSYLDEPNNTKLQIKNEHINIELYILAQNESIEQGERQLTATVITNPFKAQFQFDSTEVEIESIKWHSSLSMTVVWKRVNIDLPNEPFSIQYEVQNTQELVASFLVFLGYKMLLPYSNANIRILLP Conpu1 ELAAEIAAR--KRSTG-ERNIKLTVVLTFVRRQSGLDSRAALFVRSLQDALYEPAVEYYTAHSKRVRRKRN--RVRYEYKMACFAE-FRREDEVALKHYQDAYASLLIMAEAKVLADAINIKIVKLYLYNNEALSRHSGHMRRFSETFEF-WSWLARQHRVLAETEARRERLTNERKVHLTIILELYTKAYEFKRYGRLTLWIAGRIAMTYEQ-AGDTERAC-QFFSRIAKTYRRERWHDVLLPLLHACAQKLEVAVRLLVEMAG------TAPLLDTNVVFWTASFQITISLGEETSLRKLVLAGKISIEVTLHWSSVHHEQALLDEDYPIVISVTNTDLDVAIDALAPGVSTQKGERVIDVSVQLEALRVIYDVGPVGLKVDSAKLGDEFGYEITWRRGLLSVPSVPTHMHLTIRNTATVTVQLILVAGLRVLLPGMEYTLSVRVP Copci ELAAEIAQR--KRGTN-ERGVKLTVVLAFIRRQSGLDSRAALFVKSLQQALYEPALEYYTAHSKRVRRKRN--RVRYEYKMACFAE-FRGEDEVALKHYQDAYSALIIMAEAKVLADCINIKIVKLYLYNNEALAHHNTHIRQFNETFEF-WGWVARQYRILAETDMRRERFANEKKVHLSLVLELYTKAYEFKRYNRLTMLIAYRIAEIYAL-SGKYDMAI-RFLERIAKTYRKEGWYLMLRPLLYHCAQQMNLSIKLLLEMMGEDDEPTSLPIFETSVAFWDAAFQLSVHFLGSGHLRTVVFTGTVKVLLNLEFSFAHHTPSYLDEDYEIHIQVTNRDLDVTVDILLPGMTASKGDRALDISVTIAPFDISDNVGPWGIFVESAAVGDEFSFILSWRRALMDIEPKPMPMTIIVRNSANVTVQLFVVSGVRVLLPGSEERIYVRVP Croqu1 QLIYEIVER--KKTTA-ERGIQLAVVLGYVRKQSGLDSRASLFTNTLKTELYETCIDYYREHSRRVRRKRS--RVRADYKLATFAE-FRQEYDVALKFYEDCWEGLSQMAEAKVLIDCINIKICKFYLYSQESLDQFRKHTARFRETFEF-WSWLSKQYTILADAIHRRDKLAYERKVHSELIIGLFTKAYEFKRFGRMTLFLAFKIAAVHLD-NKDYGTAV-KFLDRITSSYRKEKFGPILESALYQTIKLEQQILRISYELLGPDKCKADISPLRSQIVFWDVDFQLTLQFTNEQDLSKLLFNGRFQIKFISPLSSSAEPFALLGETLDIKIRLWNDEVMFKIDAVGAQQSTEKGNFRISISISKEPLSCSFDTNVLLLTFNLYRSDSTYSLKITWARVTTDLPHECCTITYTIKNIAELAFQLWVCSGPRKLLPGGSRSIEIGGP CryneH991 LLIKEIGDR--RRKLG-ERGIKLTVVLSYLRRASALSSKASLFILSLQDALYESSMDYYNAHAKRVRRKRS--RVRYDWKMGWFAE-VRGEVDVARRHYEDCWNELAKMAEAKVLADCVAVRICKLSLYEGDALNSFHVHLKRFGETFEF-WSWVARQYRVFAETLKRQERFANEKKVHAALVIELFSKAYSLKDLPRTALYIAYRIAETYNL-SGQHEMAI-RFFDRISHSFKNEKWTELVQGIRYESAKAADGVGKLLLEMMCNDEEREGLELLDVRAGFWQVPYQVTIRFSDQASLRTLVINGLLSIKLVLRLATS---------------------MNVALSVLEPGASSSQ-TKIVDFSLQPRPFVVESSVGPRGMIVEGLELETSYGLVFSWRSSTLHLPTSAFPLTVTVLNSSQVSVTVFVWVGDREILPGKEVAVWVKVP Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 KLVEEICSF--KHFSN-LRKIRYLVIVEHIRMNTKLAATTGLAMLSIVHSVRPWCTDFYNALLK----------SRSSLKEALLEE-FCGVTEDSTKSMEYCYESLINSCQCRGLLDLAAIHIVRSYILLGNSYKKFAIHIQNVTDSYSY-YTWSATQMSWLAQSLMRRRKLMEERKFYSKKCLQLLNGALDFSRSRRAESYTYFQIAEEHFL-TKNYSMAI-NNYLVALPIYHEEKWKWIESILLFQCLIKLHDSAIYYLKLCSVHPLKFSIKLINVNVVFEKFTMQAVFIFGDESNLIQKIFNFDIRVKLII-----YDEVIFDGFEIPIKSFIDNNDIDYTYNVIKASQSKTE--PVLDTNFRQRTFDIRLNISYMQLILNNFDL-----LRFSYTKWAGKLPLNSIESNYLVENTLKSHCAVLTIAGESYKCGLAMPNILVSLP Dicdi QMLQQVDLV--RTNMK-SRNIKLIVIVNTIRKKADIDPKYFLFVKKWERLALELSEQYYKEMCQYTKSQIA--KIRYNFKIAFYSEFFRGDNSTSLKYYRDCY-NLLNYAEIRSLASFFNFKICKISMLNSDSLNQFEKHIKTFKKEFTH-CIWLAREYQIFAEQGNRRDSIAIELSLYTNLIIKTLVKAYDSTVSGRILSFIESLIAYEYFI-SKQYDLAL-KYYNKNAFTYRREKWTTLLTHSLLKSVHYLTNYIGYALDYLSTVADRANIPLLDCRVQFPSTEFYVVVIFSERQDLISRLFTFKLSVILELERSSIHSSPAIVNEFYEIELEIINNDKGGTIRFIKETKSFKKDENKLLISISVVGFNTQFQFLPFNIIIENTKLNTTYSFIIEWRRAKVHVPSQPLTQSIIIKNLQEFDLQVFFFSGDKSIHPDSTHEIKLNLP Dmel ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 ELAREIADR--KKTTN-ERGMKLTVVLTFIRRTSGLDSRAALFVKSIQQALFDPAIEYYTSHAKRVRRKRN--RVRYEYKMACFAE-FRGEEEVALKHYQDSYSTLEGMAEAKVLADSMNIKICKLFLYNAEALSQLNSHMRRFCDTYEF-WSWVARQYRIFAETERRRLRFQNEKKVHLGSILELYTKAYEFKKYSRFTLSIAYRIAQTYYE-SGKYDMSV-RFFERIARTYSREKWGALLQPLLYACAQQLEMSIRLLIEMVATEDDEGTPPLFDCSVIFWAVAFQINIFLSDDANLTTIFIVGTFRVTAFINVSSVHRDPAYLDEPYPISIDVTNNDLEFSLDVLHPGTTACKGERMIDVSVQVAPFVVAHQTGASCVLIDSMKLGDQYSYSFIWRRALLNAPPQPFLLELIIRNSACPILSLFVAAGIRTLIPGAEEKIAVPLP Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 ELAADVAQR--KKITN-ERGIKLTVVLTFIRRQSGLDSRAALFVRSLQQALYEPAVEYYTAHSKRVRRKRN--RVRYEYKMACFAE-FRSEDEVALKHYQDAYEMLTIMAEAKVLADCINIKIVKLYLYNNEALSHHNTHIRVFGETFEF-WSWVARQHRVLAETEMRRQRFTNEKKVHLAIINELYTKAYEFKKHSRLTLWIAYRIAQTYYD-AGKFDMAV-RFFERIAKTYRRERWSSMLRPLLYACAQQLELSIKLLVEMLGDSDDPSSLPIFDSDVVFWSAAFQLTFLFSEKGNLCTVVFTGSMSVVLTIEYHSTHHAPAYLDEDYPIEIEVTNTDLDVIINVLAPGVSATKGDRMVDVSVQVNPIQASHDVGPWSLSIESVELGDEFSYAVTWRRALLDVPPVPISLTLTIRNSANITVHLFVVSGLRVLLPGSEEKLYVKVP Ganpr1 WLVTEINER--RKVCN-ERNIRFAAVLGSIRRGTSLDSRTGLFLAELQKMLHEPSTAYYRDHSKRVKKKRSRIRARYEFKAATFRE-FGGDLEGAVRHYLLAYAAILEFGEARVIVDCVNLKIMKLLLYMDLALAQFHRHLHASSGS-EW-WAWAGKQYRVFGEAEERMARIATERSVHTATVIELLTKAYEFKKHRRTTLWLAGEIARSYAS-GGKWEMAL-RFFDRIAKTYRKEKWNAILKSILLKCATEIEKVLLVLVELMSDPDERKQYPFLTCTIQFKTVPFQVTFAFSD--EFRPLVLQGSFGVALALEMTQIHSAPAYLEELYPIDVHFVNEELTAFIQLINAESSVVKSDRTVHIMVAVRPFDIAVDIGPWDVEVDKVVMGH--NFSIHWRRVTTSIPECPFTMTYLLANMHNLVVSVVVFSGPKRLLPLTQQEVRVRVP Gloin1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLYLASEIANTYLD-AGKYETAL-KFFERIAKTYRKEHWHTILESILLVCAKDLEKVVEYLIELLSSNQQRIEISFLTCRVQFKDTLFQIALSYNDDVDLNTKVFEGSIAVSLGFERTSIHSAPALLDEYYPIELTVVNLEVKTFLNAIPAGESVVKLPRTLHLTVYIAPFSFSFNTSPCEILVSDIDLGNVYNLVIQWKRAYIRIPPQLFTLVYKIINEKKIHVNIFVFSGYK-IVPGMGEHCKMKLP Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ELSAEVALR--KKSMN-ERGIKLTVVLTFIRRQSGLDSRAALFVRSLQQALYEPAVEYYTAHSKRVRRKRN--RVRYEYKMACFAE-FRSEDEVALKHYQDAYDMLIIMAEAKVLADCINIKIVKLYLYNNEALSHHNTHIRQFGETFEF-WSWVARQHRILAETEMRRERFANEKKVHLAIILELYTKAYEFKKYTRLTLWIAYRIAQTYHQ-SGKFDMAV-RFFERIARTYRREKWYTMLRPLLYTCAQQLELSICLLIEMLGESEDPGSLPIFDSSVIFWTSAFQISVFIQD-ADLRTIVFRGTMKLTLTINYDFTHHAPAFLDESYPIVVQVTNTDFDIVVDILGPGASGKKGERMIDVSIQVNPFKVTSDVGPWNLLLDGVTLGDEFCFVVKWRRALLDVPPDPITLFLTIRNSANITVQLFIVAGLRVLLPGAEERLHVRIP Lenti61 ELAAEIAQR--KKSTN-ERNIKLTAVLTFIRRQSGLDPRAALFVRSLQDALYEPALEYYTNHSKRVRRKRN--RVRYEYKMACFAE-FRGEDQVALKHYQDAYSTLLIMAEAKVLADCINVKIVKLYLYNNEALSNQNSHMRKFAETFEF-WSWLARQHRVFAETERRRERFVNERKVHLTIVLELYTRSYEFKKWSRLTLWIAFRIAQTYYE-SGKFDMAV-RFFERIAKTYRRESWESLLHPLLYKCAQQLDLSVRLLAEMLGSADDPDALPIVDAAVVFWDAPFQILIHFSGEGSLRTIVLTGSVKLVLTIDHSGVHYGPAYLGEEFPIEINVTNGDLDIVVDVLAPGVSVLKGDRVVDISVQIAPLTITHSTAPAGIVIESVVLGDELCYEVTWHRALLDAPTTPAPLRLTVRNSANVTVQLFVVAGLRILLPGAEESVLARVP Malgl1 ALIEVISAL--RASLA-PRGIKLMVVVAHLRRASGLDARGALFVTSLVKASEVLTSDYYREHARHVRRNRA--RIRTHYKLGALAE-LQGDMAESHSMYAEAYKTLMQQAEAKVLADTLSFKLIKLFLYDMKARVQFRQHNLHITQTHEY-WAWLAKQYTFMADQMERARCSSREARVHTALIVPELDRAYKFQQRRRLAHLVAVRLALTLAE--TQPKRAL-NYLTRTLQWYRRDPWHELSYALVLACAIRCNLITRMEHECRILVSKRTHMRTIYARAAFAR------VYLAGVACFSPLIVNLRFRVECVFKPHALHVPPIACGQIAPLSLISPNDALPPGIRLAASGGDVVEGQPKTHDSSRVPSFLCKAQIGPLTVQVKRVHVGDRAALVITWRSVRVSAPSAALPVQVSFINIADVQFTIWIVSGMMMLLPCEERLVIWKLP Mellp23 QLIYEIIER--KKTTT-ERGIKLVVVLSYIRRQSGLDSRSSLFVKTLKSELFESSLDYYREHSRKVRRKRS--RVRSDFKLATFAE-FRQEYDVALKSYEDCWIGLSGMAEAKVLIDCINIKICKFYFYSQEAMDQFSKHVNRFRETFEY-WSWLSKQYTMFSEATHRRDKLAYERKVHTELIIGLFTKAYEFKRFNRMTLFLAFKIAMIHFD-NQDYVTAG-KFFERITSTYRKERFKPILDNALYESIKLEEKLLEISYELIDPIETKAKISPLRSEVVFWNINFQLKLHFSNEGNLSLMIFNGEF------GLSSFNEELVLLDETGSIKVKLYNDELVFKLDVLEPRGSIEKGNRHMKLTVNKDPFLCEFDIDLIKLSLNQIQIGSALSLKITWERITNNLPPEKCKITYLIENMKTLNYELWIFSGKRKLLPGMKRSILIEIP Mnele ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 TLAQDLLER--RKASQ-ERGVKFAAVLNFVRKSAGLDIKNSFYAVNLQRSQYEGSMNYYKEQVKRHKKKRS--NFRYDFKMGMFSE-CKQDIDNAVKFYESAYGLLIDMAEAKVLADCLCLKICKFHLYLDAALFYFRRHLIVFKDSFEY-WAWLGKQYRVFGDSVQRRLRMNAERAIHLSLTIELLTKSYEFKRYKRMTLFLASEIAGTYYT-AGKFEMAL-KFFERIGKTYRKEGWNLILTSILIQCAKELENVVEYLIEMMSDAKRRSVFSFVSCAVQFQSSKFQLQVEFSDNLGLDTMVIEGAIKITLGVRAPSLFKSPAYLDEFFPVVIKVRNGEVAMEMDVSAGSGSVAQTPRTIVCKIRIPPFDAAVDYGPWPVQVKEVKLGN--LLRILWRRMTVDLPNRPFTARYEIHNTQELAMTVMVYAGTMRILPFANHSILTRLP Mucci2 HLAVEINAR--RKYFQ-EKGIKFAAVLSAIRKQCGLDARSSFFVHSLYRALYEPALHFYSNRLKKIRKKKS--KLRYDIKAAFFQE-TKQEIDGALKSYEAAYGIIAEMKEARTLADCINVKICEFHLFMNDALSQLNGHLHMFQHTFEY-WAWLSKQYRIFADCAERRRRLQNEKLVHSSLTIELLTKSYEFKRYRRMTLYLAAEIAGTYYE-TGKFEMAI-KFFERIGKTYRKEKWHMVLTSILLRCAKELERAVECLVELMSADNKRNDIAFLTCQVQIKKVDYQIIVLFNHKVDLQTKALQGSVDVCFDIHLSTAHAAPALLDELFKLDVTMTSSEVEATLIAIEPGQSLTKGSRLITITVKIAPFDANYELSAWDLDIKHVQLGHIYNIVIEWKRVLADIPSEAFTLSYTVYNLAEYNASIFVFSGYKRVLPLSRTVYKVKLP Mydma ---------------M-SSNIKILMA-----------------------------------------------K--------------------------------------------------KMSLNSTE-------------------------------------------------------------------------------------------------------------------QCINVL------------------------------------------SSDLE--------------RTSQI--------------------------------------------------------------------------YVMKWKRLRVDIPSEALIIDFFIINVQEVEAHIFMLAGNSRILPQDEHKLELLLP Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FYDRISKTYRNENWSILLTDILVKCSKETQILIESLVELLSEFSERIEIPFVSCKVKFNKAKFQLSINFNDTANLSRKVFEGVISVSLIIENTKNHDQTAFIDEVFPIELEINNVEIHAYLSVIEGGQSIKKGNKELKIKIEKIAFEISTNVNVCKFDIDTMELGSKVNLVIRWK------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ALAQEINDK--RKYFQ-DKGIKFSAVLNLIRKQSGLDAKNSFFVNTLYRCLYESALQYYSNVIKKLRKKKS--KLRYDLKIAFFQE-LKQDIEAALKTCVVAYGLLGDVTEARALADCINIKICRFHLFLNDAFSQLNGHLHLFQQSFEY-WEWLSKQYRIFADCAERRRRLSKERQVHSSLTIELLTKSYEFKKYRRMTLYLAAEIAGTYYE-TGKFEMAL-KFFERIGKTYRKENWHMVLTSILLRCAKELERAVECLIELMAAKQKRADISFLKCSVQFLNELYQISVLFSEKVDLRTRVFQGQIGVCLDLELSAIQFSPALLDEDFEMCVTVTSEEIDVTLCMIEPGQSVSTGPRLVNLKAEVSPFETTFELSTWNLDIESVRLSHVYNIVVQWKRVIADIPSEPFTLTYTIHNLAEYTASIFVFSGYKRVLPLSRASYKVRLP Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ELSAEIAQR--KKSTN-ERGIKLTVVLTYIRRQSGLDSRAALFVRSLQQALYEPAIEYYTSHSKRVRRKRN--RVRYEYKMACFAE-FRGEDEVALKHYQDAYGMLVIMAEAKVLADCINVKVCKLYLYNNEALSHHNMHMRRFSETYEF-WAWLARQHRVLAETETRRERFLNEKKVHLTIVLELYTKSYEFKKYNRLTLWIAYRIAQTYYD-SGKFDMAV-RFFERIAKTYRREKWGTMLRPLLYSCAKALELTVRLLIELLGDVEESGALPIFSTSVIFWSAAFQLSITFSDQANLRRIILAGTMKLLFTLNLSTVHNAPAYLDEEYPILIDITNEDLDIAVDVVAPGVNVLKGDRVLDISVQAAPFKVTRHVGPWGVDIESLKLGDEFSYAIVWKRALLHVPPTPIPMRLTVRNSANVVVQLFIVAGLRTMLPRTEERLYVPVP Polpo LIMSQIDTV--KANIK-QRNIKLIVVFNLVRRRADVDPKYFLFVKKWEKLALELADLHYKEECQSSKSQIS--KIRYHFKIAYYSE-FRIDMNTALKYYAFAYHSLKDWAELRTVASFLNFKICKLFLWSNNAIQQFEKHIRLFKKEFNH-CAWLSREYQIFAEVDERRKYVAIELQAYTSAIIDLLSRAYEANQHQRIISYVESLIANEYFYGSNQYELAL-KFYNKNAITYRREKWWVLLTYTLLKCVHMLTNYIGYAMDLLSSKEQRSSIPLINCRVQFPNTEIFVVTIFSDRKDLVSRIFSFTLTVILELERSSIHTPPAIINEFYQIELELINNDTSGSITFISERTSFKKDEIKLVINVSQIGFLTQFQFLPFNVNILRTTLDNNYSLNIEWSRTHVKVPAVPITHSISIYNLQEFDLLVFLFSGDKSIHPESTHEIKHPLP Pucgr2 ELIYEISER--KKTTS-ERGIKLAVILSYIRKKSSLDTRASLFIHTLKAELYESTIDYYREHSRRVRRKRT--RVRSDYKLATFAE-FRQEYEVAIKSYEDCWEGLLQMAEAKVLVDCINFKISKLYLYSNEAMYQFNKHINKFRETYEF-WAWLSKQYTVLADAVERRNKLSHERKIHGELIISLYTKAYEFKTVGRMTLFLALKIALVHYH-QNDHSTAW-KFFQRIIPSYRKGSFNTLLDSVLYRNLNALVELLKICLELIGPNGSYGDIFPVRFQVAFWEVEFQVFLKFTSTLDLHYWLITGRLQVVFRFSFESACESCGIVNKEQSLQIEISNLELNLKLAVIKSKETMKKGLRVLEFTL-EDPIQIQFSIQAFLLLLNSIKIGNSFAVAVRW--VLTDLKTEPIEVNYMIVNTADLVVKIWIIAGSKLVLPRSSMVVQINGP Punst1 ELSADIAQR--KKTTN-ERGIKLTVVLTFIRRSSGLDSRAALFVRSLQEALYEPALEYYTTHSKRVRRKRN--RVRYEYKMACFAE-FRGEDEVALKHYQDAYSMLAIMAEAKVLVDCINIKICKLYLYNNEALQHYNSHVRKFGDTFEY-WSWTARQYRVLAETEHRRERFANEKKVHLTIILELYTRAYEFKKYSRQTLLIAYRIAQTYYE-SGKFDMAV-RFFERIAKTYRRERWNSMLAPLLYKCAQQLELTVRLLVEMLADDDDEASVPLLDASVVFWQAAFQLSIYFSDDANLRTIIFAGTMRLVYTLYFNTVHSAPAYVDEEYPILVDITNFDFEVELNVLKPGVSVLKGPRTLDISVQVASLAVEFGTGPWSLQVEGVSLGDEFCYEIKWRRALLHVPPTPTTVRLTVRNAANCVVQVFVLSGLRILLPGGEETVFVRVP Rhior3 SLATEINVR--RKYFQ-EKGIKFAAVLSSIRKQCGLDYKSSFFVNNLYRVLYEPATQFYNNRIKKIRKKRS--RFRYDLKTAFFQE-CKQEIDGALKSYEAAYHSLTELNEARVLSDCINIKICKLYLYMNDALAQLNGHLHMFQQTFEY-WACLSKQYRLFADCAERRRRLL-EKLVHSSLTIELLTKSYEFKRYRRMTLYLAAEIAGTYYE-TGKYDMAI-KFFERIGKTYRKEKWSMVLTSILLRCAKELEKAIECLVELMSTESKRNDISFLSCHVQIKSVNYQITISFNDKCDLRTKVLQGLLGISFDLVLYSTHNAPALLDELFKLDITIKNTEIKATLYAIEAGQSITKGSRIVSLNVKAAPFDATFELSAWDLEIESIRLGHAYNIVIRWKRIIADVPSEPFTLSYTIYNITEYTASIFVFSGYKSMLPLSRKMYKVKLP Rhoto1 GLVQEIVDR--KRTTY-ERGIKLAVVLSLIRRQSGLDTRASLFVQSLRAELYPAAIDYYREHGRRVRRKRA--RVRYDYKLALFAE-LRNEVEVALKHFEDCYVTLVDAAEAKVLADCISFKISKLYLYLGEAVAQLHKHVSLFLDTFEF-WSWLSKQYRLFGDAVERRERLAHETKVHGEIIIELFTKAYEYKVHKNMTYAIAHQIALAHLE-GGKLDVAL-KFHDRIAKSYRQNKYDDVLADILFEAAKGVNAAVKAGLELMADVATRERVPLLECRLAFLHVPFQLAITFNDSANLATKLFVGSIKVVLTADSSVCFVSPAYLDERLPVIVDVRNDDVELFLVSLAPSASQSKGPRNIDVTIRVLPVQASFSTGPWSIEVQSIVLGDVFNLEIQWK-ILLRLPPRPVTLSYRFSNPTSRLLTLFAFAGPRTLAPFEEREMRFTLP Rozal11 IIIDDINEKKVRKQFQ-ARGIKVAIVLS----NCGLENRSTLFISTIETSMKDASEAYYKEEIKGLRKKQA--KAHYEFKIAVFYE-MRREKESAIKSYYATYTGLIEVFEEKAFSDAIILKLCHLLIFAENIFTLFKRH-----NCYNY-QARMFKLNREFAD-------IAEVKKIGGKSVIELLTRAYEFVSNSRINLFIATLIAKEHYE-CENYETAS-KFLE-------KEGWNSILEEQLSDCYMKL--------QYLNSISENSQIGFL--------LGFEISVLFSD-----KQVINFEFFVEFQMNQKTIHSEINALNENIPLKITLINNEINPNLNIVEKQKTISLSEETLETNILVHPFLISPSFLCDDLIIHSLRL--VLKLTVEFSRQISNYPSDPFIYEKIIINTESLSISIFVFSGCKNLIPQSFIKILLQLP Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 DLSTDIALR--KKSTN-ERGIKLTVVLTFIRRSSGLDSRAALFVRSLQQALYEPAIEYYTNHSKRVRRKRN--RVRYEYKMACFAE-FRGEGEVALKHYQDAYSTLIIMAEAKVLADCINVKIVKLYLYNNEALSHHTSHIRQFGDTFEY-WSWIARQHRIFAETEMRRARFANERKVHLVIILELYTKAYEFKKYTRQTLYIAYKIAQTYQT-SGKFDMAV-RFFERIAKTYRREQWGEMLRPLLYECAKLLEMSVRLVVEMLGQGEEDEALPLLKPTLVFWPAAFQIAIFFSPKANLRTIVFAGTMKLALTINAHSVQHAPAYIGEDYPILIDITNTDLEVTLDVLVPGASIVKGDRVLDISTQVEAIRASWDVGPWNLEILGMELGDEISYEVKWRRALLDAPAQPALMTLVVRNAANVHVALFVVAGVRVLLPGGEERVLVRAP Schpo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar ECAAHLTAV--RKSLE-GRLCKLVVVAISFRRACEVEGKNSLFVNRLDSVFKDLASAAIDEQAGRIRSHRV---IRHQFKLAFFNE-TLSRSHEAIRHYSSAYSELLTLNEIKAMAGLINHRSCSLQLVLNHAIELFRRHLSHFKDSFRH-LSWISRQYQVFGEAIKRHSCFVGQEMIFVNEVVELLAQARIYKRFKRMTRCIAVQIADQYLR-AQLYERAF-LVYEKVHVEYRRDGWDVLVDIVLLVCACALDRAMQLALECSSSHAERDACPIINCSVCIQSVCVSVNIAMTEYADLTYTLIMGATRVELTLSHSEAHRESNVTGEVSPILIQVTNHETDLRIELLLSGVTHDLDERALAVRLSIEPFEWQAKV-PFEIDVLSTELEHAWSMLIHWKSLETDIASTPLTVTHRLFNVQHVAFTMFMFSGYKRVLPMSSQSHLIALP Spipu1 ILCAEINEK--KRNAT-DRGIRFAVVVSFIRRTCGLDLKSSLFITMMQKSLHDSACSYYRDHDKRIRKKKA--RLRYEYKLAVFAE-FRQDMENAIKHYETAYQLLIELLEARTLVDCINLKICKLHLYTDRALQQLEKHLTNCKGSFEY-WTWVSTQYRVFGEAEERWKRLASERSVHATLVIELLTKSYEFKKHRRMTLFLASEIARVYEQ-SGKYEMAL-KFFERIGKTYRKEHWPNVLKDVLVQCARTLDVVVECLVELMSNAEQEAAVGFLQCNVQFKKAPFQVVIGFSDKVDLETQVLEGVVTVSVVLEQAALHAPPGYIDEVYWVVVEVVNEEIEAYLDLIPSLCRVSQGERVMYNTVYINGFETKFSIGPWDMEVAEVKFGHVWNMVVRWRRICVDIPPTPFTVTYELHNIHHLSLSMFVFSGCKRMLPLSSMRVKAALP Sporo1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 DLSAEVALR--KKATN-ERGIKLTVVLTFIRRQSGLDSRAALFVKSLQQALYEPAVDYYTNHSKRVRRKRN--RVRYEYKMACFAE-FRGEDEVALKHYQDSYSTLVIMAEAKVLADCINIKICKLYLYNNEALSQHTIHMRKFGDTFEF-WSWIARQHRVFAETEKRRERFANERKVHLTIILELFTKSYEFKKYSRLTLRIAYRIAQTYYE-AGKFDMAV-RFFERIARTYRREKWGSMLRPLLYACAQQLELSVKLLVEMLASDEEEGAASIFTSTTVFWDSAFQISITFSHKANLRTVVISGTVNIVLTLHCHELHYAPAFLDEQYPIVIDVTNVDLDVVLDVVPPGVSVLKGDRILDISIQTEAMKLSYDVGPWSLSVEKVRLGDEFAYELSWRRALLSIPSRPFQASLTIRNTATVSVQLFLVAGLRILMPGAEEKLFVRIP Tapde11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr EAAGAIVHD--VTAAAKATSTKVVAVLAAIRAATSLASKR-IFMAKLGKALTDLAASYYQDEARRIRREKE--AVRAYLTMALLRE-LQGE------YYKSAYSFLREV-QVLCVAELVHFKILGAYF----AATWLAPSHLAYAHA----W--VARQYHVLAATSRRAASAALEATVVHALVLRFLTLAHDYNAERRTLARIGRLMAEAHYD-AGNYDKAL-VFYQRLYPVFAGEAWHAITVDMLVVAATAS--------GALT----EY--APLEVRAE---------LDLTEAILLR--------KVTAAVPIAPVHAPPALIGERYPV---------RVTLTAAASMMSMTSAEIALRAVIECEPF------LPW--VVGEVAYGATVSVSVTWRRAVLHAPREPFPVELDIVNSVPVEVTLFVFGGDRHVLGSETRSVREDVA Treme1 MMIREIADR--RRRLG-ERGIKLTVVLSHLRRSSSLSSKASLFVASLQESLYDSAMEYYANHIKKIRRKRG--RVRYDWKAAWFSE-IRGDLDIARRYYEECWNELVRMAEAKVLADCVAIRICRLWLYSGEVLEPFNLHLHRFGETYEF-WSWLSREYRIFAESVERKRKLNTEKTVHAALIGEV-SRIYAKKRERRVALYMSFRMAEVYCQ-AGQYEMVM-SHFDKLAEEFRRDGWPIVVRQIRYEAAQRTEVAARLLWEMLAETEDRSALAFLDIKAGFWEAPFQITVVFSDQTALRKLTIHGQVSVILELELSPTYHPSGYVDEVLPIMIKVTNPELEIQMSVLSQG-NLEK-SKTIEISIQLYPFMLSSTVGPRPLHVESLK-DTAFSLVFQWRTS--HPPSQSFNPILTLKNPHVLNVLVFVWSGPRTVGGGEEKEVWRKIP Trire2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 AMAHGINEK--RKYFH-ERGVKYAAVLAALRKLSGLDSKNSLFINNLFRSLYEPAQVYYSNHVKRVRKKLA--RVRYEYKLGVFQE-FRQDIQGSLKSYDAAYNMLLNMKEACILADCMNIKICRFFLFQDNALAQLNKHLHAFQRSFEY-WSWLSKQYRVFAESAERRRRLPEEEQVHSALTIELLTKGYEFKKHRRMTLYLAAEIAGTYYE-AGKFEMAL-KFFERIGKTYRKESWHTVLTSILLRCAKELTSVVGYLVELLCSQDKRSELSFLTCHVQFEKIHFQISIIFNNNAGLQSKVFEGTVTVMLELEISAAHYAPALVDEHYPFFITLTNEEVDAVIRVIEGNGSKEQLTRLLNISVRNKAFEVKFHSSPWNLQVVSMEMDQVFNLVITWRR-VSNIHE----------------------------MPLCQTSIEIRVH Ustma22 ALIKTIADR--RRSLA-ERGIKLTIVLSFVRRSSGLDSKASLFVSSLHGALFESAADYYREHARRVKRKRT--RVRSEYKLAVFAE-LAGDMHEAALRYREAYDLLCNSAEAKVLADTLSVRICKLLLYADDAAVFFRRHLARFTITFEY-WSWLAKQYRMFGETVERRQRLSHERKVHTAQLTESLTKAYDFKRNRRCALLVAARIATAYHD-GGQNEMAL-KFLERILKSYAKDEVHCVRAGLVVQAAIGATSAMKMLIEVLDEMHNRDKMRFLHMDTAFPAVPFQVVIDSCNSGTIA---FQGHIRVSVHLNPSVTLATPTYIDERIALTVRVSNHEVQVWIDAVDAGGKVERGVRVVNVTVR---VHKAFECGEQAVTVSKVEVNDRFSWRITWSRLLMPLPVN--THAW---HSLSVLLTLFTLAATRYVLPGQQLDLTFALP Walse1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3804.fasta_al_trimmed; alignment length = 122] Allma1 FKNLYQRRRAAT--DRPCWVCGKPTQEVL---THSDIDFFFTCANHCQDPGFCTLSP--PNTGAATTTGRAPAGTTSAPK-SDESAATKPTYVLHSRIFSMRAAEYREKQRVKAKQS--PSV Ashgo11 -------------------------------------------------------------------------------------------------------------------------- Aspfu1 LPNVWHLRRVADTAAKACFVCYKPSASVLI--TPDNK-------------------REIEIVKKEYEEKQRRKKKEKKASDKKSKKSDKESFALHKNFYQMRVDRQCNIEMAKRNRQ-FPSV Aurde31 FKNVYYKRAVAT--AKPCFVCFKPTTTVLA--TMDATDFIYSCDLHLSDAGFASRIDEILKIKQEWDERQ-KRKKEQKDKDKKDDDDTKKNYSLHRDIFAMRQSEHRKRRNAAQAKE-IPSA Batde5 PTFLYQHIQMDAVKPGTCFVCNKESQNVL---TNGAGDWFYVCISHTSDRSFCRP----EKVSLPAPSKPNPEKVEPKSTDSKPAEKTPDAFTLTSNFVYLRQNYHKKREQAKSAKA-LPSV Botbo1 FANLYYQRAVAT--ARPCYMCLRPTTIVLA--TINNTDFLYTCATHLTDPGFATPLEELKRIKEEWEQKQ-KRKKKQEEADKADKGDKEKGFVLHREVFAMRQAEHRKKRQTSQIKE-LPGA Botci1 FPNIWTHRKVADTASKPCEICYKPSASVLI--TPENKDFFYVCPSHLKDKGFATPIDEVARVKQEFEEKQKRKKISKKDDKKDEGKKDEKKFSLKKAFYQQRLDRKRQAEVAKRNRE-FPQV Caeel -------------------------------------------------------------------------------------------------------------------------- Canalb1 FPNKYHVKLVASSDSKACLICYKPATTVLL--ADGNGDFFYTCPQHLLDNQFANAIDKKSKLEKDVES-WKQK------D--KDKDKYTESYQLNQDIYKNRLMFHQKKKYNQQRAV-FPSV Cangl -------------------------------------------------------------------------------------------------------------------------- Capow -------------------------------------------------------------------------------------------------------------------------- Catan2 FLNAYKHHVATS--DRACWMCGKLTTNVL---TCQDIDFFYICANHIKDAGFC---P--AATAVATTDGTAP----KTP-----SAELKPGYELHSRVFGMREQKYRDKQREATKAK--PSV Cioin -------------------------------------------------------------------------------------------------------------------------- CocheC53 MENLWHLRRVADNAAKACWICYKPSTSVLI--TPSNKDFFYICAGHLTDRGFCQPEREIEAVKKEYEQKQQLKRKSKDKKEEKAKEEDEDKFQLNKSFYQMRLDKLRNAEIAKRNRE-FPSV Coere1 PENLYIQRTAAA--EGRCFICNALTATLLIT-EKHPVDWFYICQSHLRSNGFCTMA--VSTVAPDSVDTEPMGSSNKGSDDKGSSNGSRAAYILHSDYFYLRKRPFILRWEQEQEYL-LPSV Conco1 VQNQWELKTTKN--EGTCFICSKFTTGCLVY-KFGQIDWFFTCLSHLEDPGFARVL--SSNVKAEENKDSDNSKKAKTDKDKEDKTEEKKEYQLHRSILYLRENQLKLKSNKVKLGQ----- Conpu1 FPNLYYKRAVGT--ERACFVCYKPTTTCLA--TIDSADFLYACTTHLSDRGFATQVEEIDRVKKEWEEKQ-KQKKEKEKKDSKDKSANKSEYTLHRDIFALRVAEHRKRRQTAQAKN-LPGA Copci FQNIYYKRAVAT--AKACYVCYRPTTTVLA--TINTVDFLYTCPSHLTDFNFASRIEEIEKVKREWEEKQARKKKAKTEENKKDENSESSKYSLHRDFFAMRQLEHKKRRQAAQAKS-LPGA Croqu1 -------------------------------------------------------------------------------------------------------------------------- CryneH991 -----------------------------------MEDWLYTCDGHLSDP--ASLIEDIRKVVAEYKAREAEKSKDKGGKD-KGKESPKSPFALHRAIFDMRRNELKRREMGVKARE-LPQV Crypa2 -------------------------------------------------------------------------------------------------------------------------- Debha1 FPNHYHARLVAEKDSKACTLCFKPTTTVLI--SQNKVDFFYVCPLHLKDEHFSTAIKKIEDSRKRVER-LGSKK-----E--KDKDK-EKEYTLNKDIYRMRTQNYAQSKIRAKKQQ-FPSA Dekbr2 FRNSYCERKVATSDAKSCLICFKPSTSVLI--TDNSKDWFYVCPSHLSDANFCSTVRKSKQLELEIESKWGKKKKDDNEDDAKEDDTTKKEYKLDQVFYRNRLLSDYKKQKRAQIRK-FPSL Dicdi -------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------- Fomme1 FANLYYKRAAAT--EKACFICSRPTTTVLA--TKDSVDFFYACDGHLKDHGFASLAEEIQKVKEEYERKQQKKEKDKADEKAKETEKTKSKYTLHREIFAMRLGIHRKRRQTAQAKE-LPSA Fusgr1 FPNLYTHRKVADSAAKACDVCYKSSTSVLI--TPDKKDFFFVCPVHLKDRYFATPKEEKERVLKEYEEKQKKKKAKKDKDKDKDKDKDEKKFELKT-------------------------- Galma1 FTNLYYKRTAGT--PKACYVCDKPTTTVLA--TVNTVDFLYTCPGHLSDSGFATLIEEIAKVKAEWEEKQ-KKKKEKEKKDK-DNEKEKEKYALHRDFFSMRQSVHRKRRQASQAKE-LPGA Ganpr1 ISTEYERRTATA--ERGCFVCGKITTTVLH--GTDNMDWFYVCPGHLEDRNFCKWLP--PKQAAPPPK--PPAPKASPP---KDSTAAAPAYALHRDFQYLRMQHKKEMAAKKAR------- Gloin1 --NLYTHRIATT--DKPCFICNKYTSSVLR--TDNGLDWFYTCESHLSDRGFATPIPVVQSTRVSISQKDDSSKSKSDPDKSNDSTKVESKYKLHSNIFYLREDKLNKKRQKEEAQK--PNV Hisca1 -------------------------------------------------------------------------------------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------------------------- Lacbi2 FTNLYYKRTAGT--AKACYVCSRPTTIVLA--TINTTDFVYTCPGHLSDQGFASLVEEIKKVKEEWEEKQ-KKKKQKEKKDKTDDDTTK--YVLHRDFFAMRQSEHRKRRQVSQAKE-LPGA Lenti61 FTNLYYKRAVGT--ARPCYICNKPTTTVLA--TINTVDFLYTCDTHLSDPGFASQVEEIAKVKAEWEERQ-KKKKEKEKKDAKD-DEKK--YTLHRDIFALRLAEHRRRRQAAQAKE-LPGA Malgl1 -------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------- Morel2 LRNAYIEKTATT--ERSCFICMKMTTKVLT--AKDGGDFFYICPSHLQDPGFAKGEEALAAVAAIRKKKEEAEKSTTPADKRSHAAKLGSAWVLHRDIFYLRQVEAKKKVAKKT----FPKV Mucci2 LQNLYVARLVTQ--ERPCFVCSKFTGVVLTSADNSNTDWFYVCRAHLGDFNFCSKL--NAQVKKEQLANRPPESKKKEDNKEKDEAKEEEKFVIQRDYFYLRQREYMKKIQKKQASE-FPEV Mydma -------------------------------------------------------------------------------------------------------------------------- Neucr2 FPNLYTHRKVAETKAKSCDICYRLSTSVLI--TADNKDFFYICPSHLKEPAFCTPKEEIERVKKEYEEKKKKKEKEADKDGEKSKDKDEKKFELKPTFYQQRLLKKRQAEIAKRNRE-FPSV Orpsp11 -------------------------------------------------------------------------------------------------------------------------- Pench1 LTNVYHVRRVADTSAKACLICYKPSTSVMI--TPDNKDFFYVCPAHLQDKHFCSPIKEIEKVKKEYEEKQRRKKKASSKKDKDTSESNANDFSLHKNFYQMRIDRLRNIEMAKRNQE-FPSV Phybl2 FQNLYVARLTTQ--ERPCFVCSKFTSVVLTSADNSNDDWLYVCRSHLGDTNFCDKLPVSPRLKKTNLEDRKPESKEEKDKENKDEEKKKEEFVLQKDYFYLRQREYIKKNEKKQAKE-FPEV Picst3 FPNSYATKKVADSDAKPCTICYKPATTVLL--NDNKMDFFYTCDLHLQDEHFATPLKNLTDLKTKMDA-TLTN------E--KSANKSNNEYKLNQDVYRGRIQNYIKAKMNQARTQ-FPTV Plicr1 FTNLYYKRTAGT--PKACWVCFRPTTTVLS--TINTVDFIYTCPSHLTDTGFATPIEEIAKVKEEWEQAQ-KKKKEKAKANGKDADPKP--FTLHRDMFALRQAEHRKRRQTAQAKE-LPGA Polpo -------------------------------------------------------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------------------------------------------------------- Punst1 FTNCYYKRTAGT--SKPCYVCYRPTTTVLS--TANTVDWVYTCDGHLKDPGFASPLEEIAQVTKEWEERQ-KRKKEKEKDDKKDDDTDKDKYALHRDVFAMRQHEHRKRRQAAQAKE-LPSA Rhior3 FQNLYVARLITN--ERPCFVCSKFTNVVLTLADNSNKDWFSICKVHLGDFNFCTKL---KVVKKEHKGQ--PESKKEE-KEEKEEEKEEEKFILQKDYFYLRQREYSKKLKKKEANE-FPEV Rhoto1 LVNLYHVRTVAT--SKSCWICHRETTCCLA--TEGVTDFIYACKSHLLDPGFAKPASEIDKVKQEYEEKQ-KRK-----KDAESSSSTTAGLVLQRDFFRMRQEQKRREWEKKDAEKSFPKA Rozal11 -------------------------------------------------------------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------------------------------------------------------------- Salro -------------------------------------------------------------------------------------------------------------------------- Schco3 FDNVYYKRAVAT--AKGCYVCYKPTTTVLA--TINTTDFLYTCPAHLTDPNFATQLEEIARVKAEYEEKQ-KRKKAKEGKDKEKKDDSKASYALHRDFFAMRQAEHRKRRQAAQAKE-LPHA Schpo1 FENFYTLRQVSEVDKKPCFICYKPTKWVLI--TKTKLDFFYVCYNHLQDRGFATPISVIKSVTNKIDTKDESKNTGNPQEKEKDVDSASAEYNLHRDIFQMRIRYHANRAAAEKTAR-LPSP Sorma FPNLYTHRKVAETKAKSCDICYRLTSSVLI--TPDNKDFFYICPSHLKEPALCTPKEEIERVKKEYEEKQKKRKKGKESDDEKNKDKDEKKFELKPTFYQQRLLKKRQAEVAKRNRE-FPSV Sphar -------------------------------------------------------------------------------------------------------------------------- Spipu1 MSNLYTQRTATS--EAPCFVCSKFCITVL----TNSVDWFYVCPSHISDAGFCKPAP--PRSVTSPSSQISVASRPSTPKPSKDTDVSQPAYILTNNIYYLREAQQRKKAQQRVASQ--PSV Sporo1 -------------------------------------------------------------------------------------------------------------------------- Stehi1 FTNVYYKRTTGT--PKQCYVCYKPTTTCLA--TANTVDFIYTCDSHLSDPGFATQLEEIAKIKEEWELKQ-RLKPDKSKTDK-DGDKEKK-YSLHRDFFAMRLGEHRKRKQAKQMQE-LPGA Tapde11 HVNKYKKRLVAQANEKSCAICYRPTDVVLM--STDAKDWFYCCAKHLKDPGCASPIIEINRVKAEYEQKQKKKAEAKEASNPFSGTTKEEKFALHRTMYQHRVNLKQQAAQQKARDA-FPSV Thetr -------------------------------------------------------------------------------------------------------------------------- Treme1 FQNIYYQRATAT--DRPCYVCLRPTAVVLW----RAEDFFYVCERHLSDP--ATLIEDIKKVIADHHAREERKKKD---KDSKGEEKKSSRYTLHRHIFDMRRAEVKKRALGQQAKE-LPPV Trire2 FPNLYTLRKVAESAAKGCDVCYKPSSSVLI--TPDKKDFFYICPAHLKDRYFCTPKEEKERLVKEYQEKQRKKKKEKDKDKNKEKDKDEDKFELKIAFYQQRLQRKRQAEAAKRDRE-FPSV Umbra1 MKNQYILRATAS--ERPCFVCSKFSSVVLTSADNSNEDWFYVCKSHLNDANFCSRNPASPKPPVAKNTDAKPESTKSDDDKQNEDAKKTTSYILHRDFYYLREREVQKRKAKKDAAA-FPEV Ustma22 PSNVYIHRQAGT--PKSCFVCYKSSPHVLVSQSIPTLDFLYVCHAHLADRHFATKLDEIAKIKAEYEAKQ----KAKESANKESKPLSAMGYALHREFYAARVRDWNHKMVKKKEKE-MPPA Walse1 -------------------------------------------------------------------------------------------------------------------------- Zygro1 -------------------------------------------------------------------------------------------------------------------------- [Cluster3806.fasta_al_trimmed; alignment length = 47] Allma1 ----------------------------------------------- Ashgo11 SQYFDPCQESANMSMKCLERNYD-RDLCREYFDAYRECKKQWLSARR Aspfu1 ----------------------------------------------- Aurde31 TKFVDPCEDAARAAEQCMLRT-E-RDRCLDFFQAYRDCKGTWLEQRR Batde5 ----------------------------------------------- Botbo1 GQHIDPCYESSKASMDCLNKNYD-RDSCLHLFQAYRDCKSAWLEQRR Botci1 GEYFDPCQEAASRSLKCLARNGD-RDMCTDYFQAYRDCKKQWIEQRK Caeel ----------------------------------------------- Canalb1 SKFYDPCEESRMASMDCLYRNDD-KYACQEFFDAYRECRKDFFRKKR Cangl SQYYDPCQESAKMSFKCLELNYD-RDQCKEYFDAYRECKKQWLEARR Capow ----------------------------------------------- Catan2 ----------------------------------------------- Cioin ----------------------------------------------- CocheC53 SEYYDPCQEAADRSIRCLKRNGE-RAMCSDFFQAYRDCKEQWQAARK Coere1 SRFMDPCAIEAKASYKCLDENYK-KSTCDSYFDAYKECKKLWMDERK Conco1 SRYFDPCEEESKKSLKCITENGN-KYACKDLINAYKECKKEWTNIRL Conpu1 SSF--PCEGAAKASMKCMDKNYD-RDKCLDFFQAYRDCKKTWLEKKR Copci SKFIEPCAAASKASMDCLDRNYD-RDACLEYFKAYRECKNTWIRQRK Croqu1 ----------------------------------------------- CryneH991 SKFVDPCEAARKASLDCLERTYN-RSECTDFFTAYKECKGNWLAQRK Crypa2 SEWLDPCQEAASRSIRCLNRNGD-KAMCQEYFQAYRDCKKEWV---- Debha1 SKYYDPCEESRQASINCMLRNED-KTVCQDFFDAYKECKKDFFNKKV Dekbr2 SKFYDPCALSSKMAVRCMENHEDYKTVCAEYFKAYRECKKVWMEKRR Dicdi ----------------------------------------------- Dmel ----------------------------------------------- Enthi ----------------------------------------------- Falba SLYTDPCAMEAKASLRCVEQHVDIKTVCSEFIQAYNNCRKQATLERK Fomme1 TKFVDPCEEASRASMECLNRGYD-KRKCKAFFDAYNDCKKAWIERRR Fusgr1 ----------------------------------------------- Galma1 SKFIDPCAAASQASMDCLNRNYD-RDACLEYFQAYRDCKNAWIKQRK Ganpr1 ----------------------------------------------- Gloin1 SKFLDPCQKESLNSMECLDRNYD-KGKCKDLFILYRECKKKWLEKRR Hisca1 ----------------------------------------------- Klula1 SEYYDPCQESSKMSFKCLELNYD-RDLCHDYFDAYRECKKQWLKARR Lacbi2 SKFIDPCAAASKASMDCLNRNYD-RDACLDYFQAYRDCKNSWIQQRK Lenti61 SKFVDPCAEASKASMDCMNHHYD-RDKCLDYFQVYRDCKKAWMEQRK Malgl1 ----------------------------------------------- Mellp23 SKLVDPCQAARTAAHKCLDRNYD-KTQCNDYFEVYKECRKRWIEESR Mnele ----------------------------------------------- Monbr -----MCAQEKAASYACLDRNYD-RTKCTAFFDAYNECRKRWQKARS Morel2 SQYLDPCQAQTKASMKCMDENFD-KKKCTRFFKDYSDCKRKWLETLR Mucci2 TKYMNPCALEEKASMKCLDENYD-KRQCDYYFMQYKECKKKWMENRR Mydma ----------------------------------------------- Neucr2 SEYLDPCQEAAQRSIRCLHRNGD-RTMCSDYFEAYRECKKQWIERRR Orpsp11 ----------------------------------------------- Pench1 SEYYDPCQDFADRSLKCMKRNFD-REMCHDYFQAYRDCKKNWLTQKK Phybl2 TKYMNPCSVEEKQSMKCLDKNYD-KSKCDYFFIQYKECKKKWLEDRR Picst3 SKYYDPCEESRQASLNCILRNDD-KLVCQDFFDAYKECRKDFFNKKR Plicr1 TKYTDPCRDAANASMKCMDDNYD-RESCLEFFQVYRDCKRTWINQRK Polpo ----------------------------------------------- Pucgr2 SKLVDPCQAARKASHRCLDRNYD-KSLCYDYFEVYRECQKRWVDSRK Punst1 ----------------------------------------------- Rhior3 TKYMNPCALEEKQI--------------------------------- Rhoto1 TKFADPCEIARQESMRCLNDNYD-KGKCTEFFQAYRDCKKTWLDQRR Rozal11 ----------------------------------------------- Sacce1 SQYYDPCEESSKLSFQCLERNYD-RSKCQEYFDAYRECKKQWLTARR Salro SRFVAPCKQEKQASFKCLDDNYD-KTKCQEQFDAYNACRKRWMEARA Schco3 SQYVDPCKAAQKASLKCLDRNYE-RMPCQGYFEAYRECKKAWVEQRK Schpo1 ----------------------------------------------- Sorma SEYLDPCQEAAQRSIKCLHRNGD-RTMCSDYFEAYRDCKRLWIEKRR Sphar ----------------------------------------------- Spipu1 ----------------------------------------------- Sporo1 TKFADPCAQAREESMKCLDRHYD-KPKCTE----YRDCKKEWLNQRR Stehi1 ----------------------------------------------- Tapde11 ----------------------------------------------- Thetr ----------------------------------------------- Treme1 TKFADPCEAASKATYDCLERTYN-RSECQDFFRAYRECKGKWIKQRK Trire2 ----------------------------------------------- Umbra1 TKYMNPCQVEEKQSMKCLDKNYD-KSKCEYFFLQYRECKKKWLAERK Ustma22 SKFTDPCAHAAKLSMKCLDDHYD-RSKCADVFHQYRQCKTAWINQRR Walse1 TKYNDPCADAAKKSFECLEDNYQ-KDNCREAFENYRS---------- Zygro1 SQYFDPCQESSRMSFNCLDRNYD-REMCKEYFDAYRECKKQWLRARR [Cluster3809.fasta_al_trimmed; alignment length = 87] Allma1 --------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------- Aspfu1 --------------------------------------------------------------------------------------- Aurde31 RRTGDFAFHEVDGLYILSVEARHFVFDHFLPHPIALLARRRNTYFVPRESFNIVGM--FSNPMMMLMVMMFAMPSIM-DPETMNEAK Batde5 TESGDFNFPAVRGSHLLQVLCLQYNFPKIVDIPLVLEPLGSFNFFRQREGFSIMSI--FANPMLLMSLLFFLLPKIV-DREAVEEYK Botbo1 AHDGGFIFRDIDGTYTIDVNAPDHIFPQL-----QFQATYRKSYEMPKASFDLIGM--FTNPMMLMMLMMFAMPMLL-DPELIKEVE Botci1 --------------------------------------------------------------------------------------- Caeel RQDCTFRVDFVPGTYIVQIENTDFVFEPILPYPLRLSARGPARYFRKREEWRITDM--LFSPMVLMLVVMLILPKMN-DPELKKEME Canalb1 --------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------- Capow RLDGSFELLDVPGVHLLEVVHPSYMFEPVLAYPLKLQARGAAQFFQRREGVDIRGM--LMNPMVLMMIMAYAMPKMM-DPEERRQME Catan2 --------------------------------------------------------------------------------------- Cioin KPDGSFTFHNVQGSYVIEVLSPKYMFEPVVKYPLDLKPLGLVKYFQTREKFSIFDM--LKNPMVLMMLMLVVLPKLQ-DPEFQKEME CocheC53 --------------------------------------------------------------------------------------- Coere1 QSDGSFVVDNLEGDSLLEISAVDYAFPKILGYPLQIEASAKYDFFTPRQGFDIVAM--FSNPYMLMVVAVFLLPKLI-DPEAMKELQ Conco1 SVKGRFVIHGVPGQYRLNVYSPEYYFEQYLPLPLKISPKLKYKYFKDKPSFNVYSL--LSSPMTLMTVMIFFLPKLM-DPEVLKEVQ Conpu1 TRNGTFSIPDVPGAYVLSVISHDYVFDQLLPYPVVLVPRHKNNYFTPHESFNLLGM--FQNPMMLIMAMMLAMPYIL-DPQTLEELK Copci THTGHFTIPNVPGTYILSIISHDHVFDSVLPYPATLSAKESFVYFKPPESFNLVSM--LSNPMMMMMVMMLGMPYLL-DPEALEELK Croqu1 RRDGSFVLQDVRGKHVLRVACREVSFLPILSYPIRLLPRARLQYVEVRAGFNPISML-LSNPMYLLMVFMMVMPKIM-DPEALAEVQ CryneH991 KQDGSFTFYNVPGAHQLEPLIPGYIFHPLLPYLLVLEPVAKENYFIPKSGLNMLGL--LKSPMVLMMIMMWGMPKLMDDPELSKEMA Crypa2 --------------------------------------------------------------------------------------- Debha1 --------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------- Dicdi ----------------LEIESMQYNFPHFLPLPLQIKATHRIPFFQQHVPFSIFSL--VQNPMAISVALIFLLPKMI-EQD-----E Dmel REDGQFMISGVPGSYILDVHHPDVFYEPVVAYPLRVKPLMPFKYFQTREQWKITDF--LFSPMVLMMLLMLVLPKMN-DPETKKEID Enthi --------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------- Fomme1 RRDGSFSIPDVDGSYILNVLSHDIMFDSFLQYPIALTPRQKANYFVEPQSFNALGM--LQNPMVLMMVLVIGLPYLL-DPEVAKELN Fusgr1 --------------------------------------------------------------------------------------- Galma1 THEGDFIIPDVPGTYILSITSHDFAFDQLLSYPISLSPREKSVYFVPPESFNLAGM--LSNPMMLLMVMMLAMPYLM-DPEALQEFK Ganpr1 RRDGGFIIRNVPGTYILEVVSATHAFDRLVPYPVELTAKGQYEYFHVREGFNYMAL--LQNPMMLMAAMIYLLPKMI-PPEELQASR Gloin1 RKNGKFVIDDVPGSYLLEISSKKFIYPKILQYPLELSARSTSEYFMVRDGFSIASL--FANPYIIMMLLLFIMPKMM-DPDALRELQ Hisca1 --------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------- Lacbi2 AHTGDFVIPSVPGTYLLSIISHDYTFDQVLPYPIVLVPRQKLLYFVPPESFNLIAM--LSNPMMLMMGMMLAMPYLL-DPESLKEFK Lenti61 TRDGTFTIPDVPGTYVLSVLAHDHVFEQMLPYPIVLSARAKYDYFVPRESFNVLAM--FKNPMMMMMVLVLLMPTMM-DPEVMEEFK Malgl1 --------------------------------------------------------------------------------------- Mellp23 REDGTFVLQDVRGKHVLRVACREFGFLRLLSYPIRLVATNRLQYVEERAGFNPLSML-LANPMYLLMVFMMIMPKIM-DPEALAEVQ Mnele QQNGSFVIPNVKGSYIVEVLNPKYIIPSVVKYPLTFRVTDRTNFFEKRETWHITDV--FSSPMVPMLFFMLVLPKIQ-DPETKKELE Monbr AKDGTFELTGIPASYLLEVVHPDFSFNAYEDVGLRVPTTSRTSYFEPRKPWNIMEL--LMNPMILMAALMYLMP----SKETMEEMQ Morel2 NKDGKFIFTNVPGTYLLEVQSPQYNYPTVLQFPLTLVPRAPTTFFIPREGFKISSL--FANPMMLMMLMLFVMPKLM-DAEQMEEMQ Mucci2 QSNGEFNIPHVRGSYLLEVQSIDHVYPKIVVYPLEIQAKAEAEYFMQRQGFNIMGM--FKNPMMLMMIMMFFMPKMM-DPEAANEIS Mydma KEDGTFVVSSIPGTYIVEVASPNYQFELMAPYPLNFFATERAAFFELREEWKVKDF--LFNPMVLMMLFIFAMPKLA-DPEAQKEMQ Neucr2 --------------------------------------------------------------------------------------- Orpsp11 KADHTFEVKNVKGTYLLQINTKNFVFDRFCNYPLEVQAVQRKDYFEPRTSLNVFAF--LKNPIVLLMGMMFLMPRLL-DEEELKEMK Pench1 --------------------------------------------------------------------------------------- Phybl2 KKNGEFEFLDIVGSYLLEIRSIDYIFPKLIDHPFELRAKLEAEYFVKKQGFNLLGM--FKNPMFLMLIAMFILPMML-DPEAMKEIN Picst3 --------------------------------------------------------------------------------------- Plicr1 TRDGSFVIPDVAGTYILSVVTHDFAFDQLLPYPITLAARAKYSYFAPRESFNIVGM--FQNPMMLMMVMMLAMPYMM-DPESLEEFK Polpo NVDGQFSFVNIPGSYILDVDSKDYVFRQMVQSPITMKPVGLPFFFEKHAPFSIWGL--FKSPMIIMMILIVVMPMMI-END-----E Pucgr2 RQDGTFVLQDVEGKYVLIVQCRTVAFPALLQYPIQLVPTAKIQYQEIKVGFNPIAML-LGNPMYLLMVFMMIMPKLM-DPEALAEVQ Punst1 TRDGHFTIPNVEGTYLLSILAHDHAFDKLLAYPPTLAAKRRNDYFVERESFNLVGM--FQNPMMMMMVLMLATPYLM-DPDSLKEFN Rhior3 KSDGQFTFHNVQGSYLLEVQSVKYVFPKIIGYPFEIQAKTEADYFIQRQGFDLTSM--LGNKMFLMMLMLMFMPKMM-NEEMINE-- Rhoto1 --------------------------------------------------------------------------------------- Rozal11 DHKGKFQIKHVDNPSVLGVFSRFYEFSSY-----SIKPLSKKIYQEQQSSFGFLSF--LMNPMILMTGAMYLMPKLL-DPEDLAEMR Sacce1 --------------------------------------------------------------------------------------- Salro KEDGSFVINDVPASYTLEVFNPKYHYMPIAGHGLEVPYIAQHKYFEERKAWSIKDI--LYNPSLLIVGLMYLMP----SKEQLEEMK Schco3 LRSGKFSIPDVPGTYLLSVRAHDYMFDTLLPYPIVLTARGKYNYYTAPTSFNALGM--LQNPMMLIMLMVLAMPYLV-DPEALQEIN Schpo1 ERDGSFTFPNVPEIYFLRLESIDYEFSEFTSYPIKVRAVLKRDYLKEPRKFSLIRL--LKSPMMLLSVLVFILPKLI-EAKALEQAR Sorma --------------------------------------------------------------------------------------- Sphar RSDGSFSVHGVAGSHVLDVYSPEYTYSGVMPYPLKLHPTGKQVYFQPRKGWSPFDL--LKNPMLLMMVMGYFLPKMM-DEETQAEMK Spipu1 EEDGSFTLPDVPGTHLLEVASHLYHFDKIVLTPLALSPRGKYDFFVPREGFNPMSL--LSNPMILMSLMFFALPKLM-PEEAVQQMQ Sporo1 QPEYHFSFPSHPGGYALRLESRKYEFQSYVIRPLRLYPLEE----LPPPSLSLVQIL-KQNPLIWLLVFMLAIPKLL-DEETLKEVR Stehi1 --------------------------------------------------------------------------------------- Tapde11 --------------------------------------------------------------------------------------- Thetr --SGRFVFDGI-SQYRVDVVSMEYEFMAALAYPLVLKPIAPAVFLTEPQTTSILSMV-LGNPMILMMGLSMLMPKLL-DDEAKEELK Treme1 --------------------------------------------------------------------------------------- Trire2 --------------------------------------------------------------------------------------- Umbra1 QKDGRFIFPEVPGNYFLEIQSVNYIFPKLVTYPFVLKAKAPAEYFFKREGFNVMNM--FKNPMMIMMLMMFVMPKMI-RPEDMEDFN Ustma22 AVDGSFIFRDLEGAYTLELVSRTHTFEQYVFHPLIIHAVKRIEYYTEAAPLTIGSLIGMGGPMMILGGLVFLMPKLL-DPEAQKELA Walse1 --------------------------------------------------------------------------------------- Zygro1 --------------------------------------------------------------------------------------- [Cluster3812.fasta_al_trimmed; alignment length = 166] Allma1 LPDEA-KAIAPFIQRAREMAPRDPAIAYWCAVRQALQKPWLLAAMDALE----------------------------TR---ASMRTAKTFLAACNYFEVLSVFSPLDDATLDKIKYAKWKATDIVKALRAGRAQ--KHARYVISALEYDDVATAVDHLRQALAAL Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 PPDEL-KFVLTYLQRAQELQAREPIVAYYCSAKLAIEQAFLLQLLDLLEEAIGNDVVGYA-HVENFALKIFVNADNEDRAGKASKKTAKTFLAASIFLELLKTFGELDPEVQQKIRYAKFKAADIIKAIKEGQAQ--RYAKFAISALQFEDIPTAIDNLQKALATL Botbo1 IPPNM-KNLLPYLQRAAELKDKDPVMCHWCAVKLGIAKAFLQELFNVLEDELLTDSAGSM-YIRKFAYKVFAQADNEDRKGGATRSTAKRFLAAANFLELLTMFEPEDGVTEGKIRYAKWKAAEIAKAYREGQTK--RHARFAMSALDYDDLDTARKELQLALDYV Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel LPPAF-KPIAHYIKIANENASRDPVIYYWCAVQTAMKRQYLTGLLTTLEDAIKNETIAQA-HIESFAEKLFNFADKKEKTGNVDKSVVHAFYTAGHVMDILSLFGEIDEPFLSSKKYAKWKSTQIFTCLRDGFAEVRKLTKYAMSAVDYEDVKAIRDNLIKALTIL Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow TPLML-KGLVPYLQRADEFDKHDPVTAYYCAAQNALKRAFLIALMDKLEEAIRNDVVAAA-HLEDFALKLFDFSDNEDREGRANKKVARSFYAASIVFDVLKSFGEMDTEIAEKHKYAKFKAVYITKCLKNGMAA--KHAKFAISALQYEDVTTAITNLQNALALI Catan2 LPDSA-KQVLPFMLRAQEMDSRDPAIAYWCAARVALQRPWLLAIMDALEEFVADENVAAA-HVENFALKIFAAADREDRAGKASMRTAKTFLAASNYLDVLSVFADLDESVKDKIKYAKFKATDIIKALKAGQAQ--KHARFAISALEYDDVNTAMDNLRKAMAVL Cioin VPDKL-KIVRPYINAAKELKSEAPVASYYCALERAMKKGFLLNLMDYAEDSSGYEVVYGA------AMELFVSADKQDRDSNFNKHLVRTFYTSAILFDVLQTFEELPDKVVSLRKYARWKATYIHRCLKNNQAE--KLCKHAGSALQYEDVPGAINLLEKCLKLL CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 IPEEL-QHIQPYIQRSQELYKFDPVVSYFCAARQAITQTFLLQLLDELEDSMKDDTTASE-HCTTLGIKVFSGADKEDRDGIATKDTAKNFIVASQLLQILAAFGDIPDKIANIIKYSKWRAVLILRAIREGAAQ--KLARWAISALEYDDVNTAIENLQKAINVL Conco1 IPEEL-KFINQFIQRSKELKTQEPIISYYCSVKLAIS------------EAITSELAGIA-YVENFALKVFQSADNQERSGNLSIKTVRAFMAAANFLEILKYFKELEGEILEKLKYSKFKAAEIAKLIKEGQAE--KCCRFAISSLQYDDLEEALRQLDKARNLV Conpu1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci ------KVITPRYRRQNQGRSAAPW-----CARKARE------------QSLGAFVALAL-ALKAQGAAIPAEAQLERRQG----------------------F--------------------------DG---------------------------------- Croqu1 SSVLQ-SNILPHSIGA--------------AAQNCLSRQFLSILLEYLEDAITNNLAARA-YVENFALKIFDGADQEELGGNPTKLTAQRFLAAASFLEVVQSLTQPESDILEKIKYSKWKAASISKAVREGEVQ--KHAKWAISALTYEDIATARKELIIALDKL CryneH991 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 VPEEIQKVIGPFIKRAKELDQYQPVISYFASAQLILEAKFTETLSNEIEDLIDDNEKSFK-LVLGFSNVIFTGADKKVRESKADKRTALDFKAASDFYQLLHLWEEKKDVVEKRVKYSKYQCARILKSIRNGQAQ--KRAKFAINALNYDDIPTAISELEKALELL Dicdi LPPAL-KPIIPYLKQSQQLEKHDLLMAYYCAIQMAMDSIPIVKILDQGDED-EAK------YVEAFAMKAFSFADTQDRAGKANKATSTTFYSAFLFFNVLEHMGEVSEEVKLKKKYASWRSVDINTAIKNGKASAEKYSKWVISSLQFDDVPSAVKNAKLSLKYL Dmel CPPSL-KSIQHFLKLAQEHDTRDVVIAYWAALQVGLKK-LLLGIMDWLEEAITNEVAAQA-HIENYALKLFLYADKQDREENFGKNVVKAFYSSGVLYDILQTF-ELSEEALHNRKYAKWKAAYIHNCLKNGTAQ--KYCKYAGSALNYDDVKTAIENLQKALKLL Enthi ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba IPLGL-KSITTYVQRAREVQDIDPIVSYYAAVENGVKQPFLLQLLGHVEPDFADLHSSRK-RVENMAARVFLAADDEDRKGTPAMKTSQNFLVAACFFEVLNSMGMPREDIDNKIKYAKWRAVEISRAIRENGIE--RLARHAASAVQYADIPTARARLEEALRMV Fomme1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 VPTGLPNAVRGFIQRAEELRNHEPIIAYYCAARKAMEQIFLVALLDHLEDAITNQDAGKA-YVENFALKVFSSADNEDRAGKAGKNTARKFFAAKLFLETLNIWGELEDEIQQKLSYARWKAVDIEKALKEGNAQ--KYSRFAISAIQYDDIETAVDNLQKALALL Gloin1 LPEEL-KFINPFLQRAQETRKREPVISYYCAAKLALDKLFLAKLLDILEEAITNEMAGEA-YIENFSLKVFTIADNEDRAGKATRNTAKTFLAAASYMDLLRIFGNINKEFEDKIIYAKWKAVDITKALKEGAVQ--KFCKFASSALDYNDVKTSVDYLNKALEKL Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 VPTIL-KDAAPFLARADEVIKADPIISYWCAAQIGIEQSFLMQLMDELEDAVKSETVAYA-YIENFALRIFLGADNQDRQGQASR--------------------------------------------------------------------------------- Mellp23 SPLEL-KSIMPYLQRAREMEKVDPVITYWCAAQTCMSRTFLMKLLDYLEDAITNNMAATA-YVENFALKIFDGADQEDLKGNSTKSTASRFLAAACFLEVLTSLNQPEADILEKIKYAKWKAASIVKAIREGVIQ--KHAKYAISALNYEDVVTARSELLLALDKL Mnele VPASL-KSLAPYLRLCKQFETRDPVVAYHCFVQKGIKKLFLLGTMDKLEEAVGNDIVASS-HIESKALQLFLFADREDRAGNF---------------DV---------------------------CRRSGRIQ--KLCRFAGSALNYQDYKTTLDNLQRAINLI Monbr LPEAM-KGMSRFIKTAALFEARTPAVTYYCVLKNAIKRPYLGGLLTHVEESIRNSEKGKL-LITTVATSLFDKANRADMAGEGTRNTADLFYRASTLYDIMDEFENGLEEVAEARKYAKLKAAHIVKCLREGQAK--LAFKYANSALQYQDVKTAVEYCLRALTLM Morel2 VPEAL-KSITPFLQRAAQLQEREPVVSYYSAAKLAIQRPFIVELLDVLEEAITSELVGYA-HVENFAIKIFGKADDEDRAGQGSQKTAKNFVAAANFLELLKVFGDIDSEVEEKIKYAKWRAADIVKAIRDGQIQ--KHCKWTVSALTYDDIPTAIDNLEKALALL Mucci2 IPEEI-KYITPYVQRGQEVAARDPVVSYYAAAKLAIATDYLSHLLDALEEAITDDLVGYA-HVENFALKIFINADNEDRAGKSSK--------------------------------------------------------------------------------- Mydma LPPNL-KQLNSYLKLAKEYDKRDPTVAYFCCCSKGIKKKFLFSLMDQLEEAVSNEIVGQA-HIESVTLSLFSWADSEDRNGVFNRNITKAFYSASLLFDVLGQFDGFTEECQIKQKYAKWKATYLHKCLQNGFIQATKFCKFAMSALQYEDVGTAVENLTKALNLL Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 PPAEL-KVITPFVQRAKELTNIYPLISYYCAANDGIKHNYLKELFDELE--------------------------------------------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 IPEEL-KYITPYVQRSQELAERDPIVSYYAAVKLAIANAYLSHLLDSLEEAIVDDIVGYA-HVENFALKVFLNADNEDRSGNASKYVSK----------------------------------------------------------------------------- Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo IPVQL-KPISPFIKQAKQLEKHDLIMSYYCALQLAVDSTFIVKILDLAEEGMELD------YVEGFAMRAFNHADSEDRAGVATKATATTFYSCYLFFDVMKQFGELPEEVKQKQKYAGWRAAEINTAIKNGIANASKYAKWVISSLNFDDVNTAIKNLKLSYKHL Pucgr2 SPAGL-KSVNPYLQRAKEMEKVDPVISYWCAAQTCMSREFLMRLLDLLEDAITNNLAATA-YVENFALKIFDGADKEDQQGLSTRTTAQRFLAAACFLEVLQSLNQPEPDIMQKIKYSKWKAGSISKAIRDGQAQ--KHAKWAISALNFDDISTAKNQLQIALDTL Punst1 LPTEL-KSILPFLQRAEEVRKAEPVIAYWSAAQLGIGRSFLGELLGVLEETIESESASAA-YVENFALKLFESADDADRTGSATRLTARKFLAAANFLELLHVFSGLSESDTEKIKYAKWKAAEISKALREGRAQ--KHCRFAISALDYEDVEQARKELRAALSLL Rhior3 IPSDL-KFITPYIQRGQELLQRDPVVAYYAAAKLAINNVYLSHLLDSLEEAITNDLVGYA-HIENFALKIFLNADNEDRAGKASKKTAKTFLAASIFLELLKTFGEIDAETEAKIKYAKWKATDITKALREGSAQ--KHAKWAISALEYDDVKTARNELLAALNDL Rhoto1 VPTEL-KPVSPYLARAHELAKAEPVISYWCALQQGMSQAFMLGLMDKLEDAFTDDVAAAA-YIENFGLKLFSQADNEDRKGKATRLTARKFLAAANFLELLSIFGEISSENRDKIKYGKWKAADIAKAFREGNVQ--KHARWAISALNYEDVETARKELRLALAML Rozal11 ------------------------------ALQLCQNTATVMQILGDLEEIFKNDEATRA-YIENFALKVFKLADDDDRAGNGSKKTVLMYKSAITFIEILNIFGEIPEDFNVKVKHAKWRMVEIAKAMKEGEAQ--KLAKYAVSALMFDDIPTAIKNLEDAIKIL Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro VPDAA-KDVKRFIKTGEALQAQAPYATFWCALEVMVPQGFVIQLMDSVESSVSDKDTGRE-SVALLAAKIFQQADREDHAG-ATMGTALKFRTASTLFDVCKAMNPDIDEVG----------------------------------------------CVRA---- Schco3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 IPKEL-QSIQPFVRRFNELEAHNPVIAYWSAAQMALSKDFLLSLIEHLEENVSDETSAKA-YVESFSLEVLVQAERNSKNG---KPDVQAYLAARDFLELSRIWGPPTEQITKSIKFCK------LRALQVASAR--SHARYAYSALDYEDTTTAIHHLKSALKLL Sorma ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar -------------MRLQE-------------------------------KEISDQDVGKA-HFERITLNLFDEADVEDRSGLSTKATVKKFLVAGNLLEAMATFGPLSESIDEKRLYCKSKMVEMLKALKAGRVN--KLCRFCMSALMYDDVETAVSNLQEALALL Spipu1 PPDEL-KFVNAYLQRAQELQTKEPIVAYYCAAKLAIDQLFLLGLMDELEEAVTNDVVGYA-HIENFALRIFTNADNEDRQGRASKKTAKTFLASSIFLELLKVFGEIDTEVQDKIRYAKFKAADIIKALREGAAQ--KHSRFAISALQYDDIPTAIDNLEQALALL Sporo1 VPPEL-KPITPYLARAHELTKADPVIAYWCAVQQAMTQTFLFGIVDNLEEAVTDDVAAAA-YIENFGLKIFAAADNEDRKGKATRATARKFLAAANFLELLSVFGEHGTENREKIKYSKWKASDIAKAFREGKVQ--KHARWAISALNYEDLETARKELREALNML Stehi1 VPQDL-KPIAPFLQRAEEVKQQDPIISYWCAAQVGISRTFLAALLTKLEDAVDVEAASTA-YVENFALRVFTSADNDDRAGHASLTTARKFFAAATFFELLKLFKTAYESHEDKIRYAKWKAADINRAIREG---------------------------------- Tapde11 LPSEL-KSLTSIVARANELESLEPAVSYWAVVQKSMEETYLLYVLDVLELELESFASGKA-KVEAFALQIFDNADREEKARNATRNTSLKFLAAATFLEVCQVFGQPEKDLVDKRKYAKVQAMRIQSAIAAGSAQ--KHAKWAISALNYEDIATAISELRKALDCL Thetr VPAPL-KPYQQYINRANELANVDPVVAYYCVVQECISREYLNELMSSLEPLLGSESEEAAIYVENFAHKVFKGADDEDRAGVASIGTALRFRAASNFYQVLRVFGPLAADIEEKKKYAKWKAVQISKAIKAGKNQATKFASYVSSSLAFHDIDGAIENLTSALALL Treme1 VPAEM-KACEQILKRAKELRRADPAISYWCAAQKALSTKFAMSLLDALEEAVTNEAAGAA-YVENFALKVFMSADNDDRNGITGKGTIRKFVVAGQFIEVLRCFNGMTEEMEQKLQYARWKAADGAKALREG----------ANSTLS------------------ Trire2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 VPEEL-KYLQPYLQRSQELQSREPVVSYYAAAKLALSEKFVISLLDELEEAITNDLVGYA-HIENFGLKVFENADNEDRAGRASKKTAKTFLAASVFLELLKTFGDIDPDVAGKIKYAKWKATDIIKAIKEGKAQ--KLAKFAISALTYDDVKTARENLLKALDTL Ustma22 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 IPQEL-KNLEPFLARARELKDVEPAISYWCVLQNALDEEFLLNLMGELEDLVIDEDAANA-YIENFALRVFIKADDLDRAGTLNKTVAQTFLASSYFLSLLTLFKNPPGDLQQKIKYARFKTTQIMNSLKN-KAQ--KHAKWAISALNYEDKDTAINQLQLALESL Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3816.fasta_al_trimmed; alignment length = 84] Allma1 RSYGHALLAGEGSAMAAYVQRIPRRGEIGLTGDEIDQYETVGYVMSGSRHQRMNAVRLRKENQVISAEERRKLLEEKTKKEAAI Ashgo11 ------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------ Aurde31 RAYGGQLLRGEGSAMAAFLQRIPRRGEIGLLPEQIEQYENVGYVMSGSRHRRMNAVRMRKENQVISAEEKRAVLEERERREALL Batde5 HDYGGALLAGEGSAMAAFLQRIPRRGEIGLTSEEIVNYEDAGFVMSGSRHQRMNAVRIRKENQVISAEEKKALLEANMKKEAEI Botbo1 RSYGGALLRGEGSAMAAFLQRIPRRGEIGLTSTEIDKYESAGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEEREKRETLV Botci1 ------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------ Capow SGYGKALLPGEGEGMAEFIKRIPRRGEIGLTSEQIEAFEDVGFVMSGSRHRRMEAVRMRKENQVYSAEERRALAEERSKRENKI Catan2 RSYGKALLAGEGSAMAAFVQRIPRRGEIGLKGEKIEEYEAVGYVMSGSRHQRMNAVRLRKENQVISAEERRKLLEEKTKKEAVI Cioin ------------------------------------------------------------------------------------ CocheC53 ------------------------------------------------------------------------------------ Coere1 GDFGKALLPGEGSAMVAYLQRIPRRGEVGMDQNMIERLENSGYVMSGNRHRRMNAVRVRKENQVVSAEEKRQMLEERLKKEAQV Conco1 KGYGGDLLAGEGEAMASYVQRIPRRGEIGLTSDQISTFEGSGYVMSGSRHQLMNAVRIRKENQVISYEEKRSMLEENIKQESEA Conpu1 RAYGGALLRGEGSAMAAFLQRIPRRGEIGLTSDQIANYEAVGYVMSGSRHKRMNAVRMRKENQVISAEEKRGILEERERREAIL Copci RAYGGALLRGEGSAMAAFLQRIPRRGEIGLTSEQIAQYENVGYVMSGSRHKRMNAVRMRKENQVISAEEKRSILEERERREAIL Croqu1 KEFGRALRPGEGSAMAAFIERIPRRGEIGLKGPQIEKFEQAGYVMSGSRHRRMNAVRIRKENQVISAEEKRGILEEKAKREGQI CryneH991 RSAFTNMLPGEGEAIMAYAERIPRRGEIGLDSEQIAVFESSGYVMSGSRHQRMNAVRMRKENQVINEAEKRAILEERMKKEGAI Crypa2 ------------------------------------------------------------------------------------ Debha1 ------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------ Dicdi GSYGGAMMPGEAEAIAQFVKRIPRRGEVGLTSEQIASFEETGYVMSGSRHRRMNAVRIRKESQVYSAEEQKALAEEKAKRENRL Dmel KDFGKALLPGEGAAMAAYIARIPRRGEIGLTSDEIANFESVGYVMSGSRHRRMEAVRIRKENQLYSADEKRALAEERQKRENKI Enthi ------------------------------------------------------------------------------------ Falba REYGGALMPGEGSAIAAYVKRIPRRGEIGLSSEQIQQYEDVGFVMSGSRHRRMNAIRMRKENQVVSAEETRAMLREREEYERTV Fomme1 RQYGGALLRGEGSAMAAFLQRIPRRGEIGLSSEEIASFESVGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERREAIL Fusgr1 ------------------------------------------------------------------------------------ Galma1 RAYGGALLRGEGSAMAAFLQRIPRRGEIGLTSDEIAKYEDVGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERKEAIL Ganpr1 RSYGGALLRGEGSAMAAYVKRIPRRGEIGLTSEEISAYEGVGYVMSGSRHRRMNAVRLRKENQVISAEERRAMLEEKMKKENKI Gloin1 RDYGGALLAGEGSAMAAYVQRIPRRGEIGLTSNEIQSFEDVGYVMSGSRHRRMNAVRIRKENQVISAEEKRAVMEEKSKKENKI Hisca1 ------------------------------------------------------------------------------------ Klula1 ------------------------------------------------------------------------------------ Lacbi2 RAYGGALLRGEGSAMAAFLQRIPRRGEIGLTSDEIAKYEDVGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERREAIL Lenti61 RQYGGALLRGEGSAMAAFLKRIPRRGEIGLSSDEIAAYESVGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERREAIL Malgl1 RAYGKQLLPGEGAAMASYVQRIPRRGEIGLSAEQIAAFERAGFVMSGSRHQRMNAVRVRKENQVISAEERQSELQDRARKEADI Mellp23 KEFGRALRPGEGSAMAAFIERIPRRGEIGLKGPQIEKFEQAGYVMSGSRHRRMNAVRIRKENQVISAEEKRGILEEKSKREGQI Mnele ------------------------------------------------------------------------------------ Monbr RDLGGALLAGEGENMLAYIERIPRRGEIGLTSDEIATFEDQGFIMSGSRNRRMEAVRLRKENQILDADARRTVAEERAKRENSI Morel2 RSYGGALLAGEGSAMAAYVQRIPRRGEIGLESDQIERYEHAGFVMSGSRHQRMNAVRVRKENQVISAEEKRALLEEKIKKDNKI Mucci2 RAYGSQLLPGEGSAMAAYVKRIPRRGEIGLSGDQIAEFEKAGYVMSGSRHQRMNAVRLRKENQVISAEEKRLVLEQKIKRENEI Mydma ------------------------------------------------------------------------------------ Neucr2 ------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------ Phybl2 ------------------------------------------------------------------------------------ Picst3 ------------------------------------------------------------------------------------ Plicr1 RAYGGALLRGEGSAMAAFLQRIPRRGEIGLTSDEIATYEAVGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERREAIL Polpo GSYGGAMMPGEADAIAQFVQRIPRRGEVGLSSDQIQGFEDAGYVMSGSRHRRMNAVRIRKEGQVYSAEEKRQFAEEKAKKENRL Pucgr2 KEFGRALRPGEGSAMAAFIERIPRRGEIGLTGTEIEKFENVGYVMSGSRHRRMNAVRIRKENQVISAEEKRGILEEKAKREGQI Punst1 RQYGGALLRGEGSAMAAFLQRIPRRGEIGLTSDEIEKYEQVGYVMSGSRHRRMNAVRIRKENQVISAEEKRGILEERERREAIL Rhior3 RQYGSALLPGEGSAMAAYVQRIPRRGEIGLSGDKIAEFEKAGFVMSGNRHQRMNAVRLRKENQVISAEEKRLVLEQKLRRENEI Rhoto1 NAYGGALRPGEGTAMAAFVARIPRRGEIGLEADQIERYESAGFVMSGSRHKRMNAVRVRKENQVISAEEKRGILAEKAKRENEI Rozal11 ------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------ Salro ATLGSHMLKGEADAIADYVERIPRRGEIGLTSNEISDYEAQGYIMSGSRNLRMEAVRLRKENEIYDAERQRQMAEAREKKNNAL Schco3 RAYGSQLLRGEGAAMAAFLQRIPRRGEIGLTSDEIAKYEDAGYVMSGSRHRRMNAVRMRKENQVISAEEKRGILEERERREAIL Schpo1 ------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------ Sphar SGYDKHMLAGEADAMAAYIERIPRRGEIGLTSDEISNFEKDGYVMSGSRHRRMEAVRLRKENQVYTADERRALAEEKKKKENQL Spipu1 RAYGGALLAGEGSAMAAYLQRIPRRGEIGLQSEEIESFEDVGYVMSGSRHRRMNAVRIRKENQVISAEEKRALLEANLKKEADI Sporo1 ------------------------------------------------------------------------------------ Stehi1 RSYGGALLRGEGSAMAAFLQRIPRRGEIGLDSDEIAAYEQVGYVMSGSRHRMMNAVRMRKENQVISAEEKRGILEERQRREAIL Tapde11 ------------------------------------------------------------------------------------ Thetr RDLGKALLPGEGMAMASYVERIPRRGEL-MSSEEIAKFEAEGFVMSGSRHRRMNAVRVRKESQIYSAAEKAAMAEAQKERERQI Treme1 ----RDMLPGEGEAMAFYASRIPRRGEIGLDAKDIEQYESSGYVMSGSRHRRMNAVRLRKENQVINAEEKRAILEENIKKEGMI Trire2 ------------------------------------------------------------------------------------ Umbra1 RAYGGALLPGEGSAMAAYVQRIPRRGEIGLKSDQIESFESAGFVMSGSRHQRMNAVRMRKENQVISAEEKRLLLEQRLKRENEI Ustma22 RAYGGALLPGEGSAMASYVQRIPRRGEIGLTSDQIEAYEKAGYVMSGSRHHRMNAVRMRKENQVISAEEKRTMLEEKAKKEREI Walse1 RDYGSDMLRGEGSAMAQYVQRIPRRGEIGLESNDIDKFEQAGYVMSGNRHKKMNEVRVRKENQVYSAEEKRKMLEERLKKENEI Zygro1 ------------------------------------------------------------------------------------ [Cluster3827.fasta_al_trimmed; alignment length = 167] Allma1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 MEKFSQFRDRGSGIAPFLPILFCFRLPLLIFVCLSYFLASLWCILGVPSIWWIDLQGVRKGGSVIAASFTSPIDPLYLAAIFDPV-FTHISLFQAILRADVASLLERPIVTFPECTTTNARGVLPLSYSKIFPISLRYTKLLSRLARLGRVKRV-GLAVKEKQDFLR Aurde31 MEKYSAFRDPGTGIQPFLTPIGAVRALLVLVLALLYLVILCRAALFVLGFLWIPVESRRRAGDIIVSNWASFVELLWLAFRFDPI-FLRASLWQIVRYTSIEQIRSRPVVVFPECTTSNGRGLLKFADVRVFIMAVRYERLACTISTTGKLKRT-GQGWEDKIAFLD Batde5 MEKYSGWRDPGTGIHPFLSPLATIKIILIAVVALLWSISLGRTVLALCGFWWISKSTLQRGPDLYISNHTSYFDILYYASSLQMV-FMQISFWEALMEAFVDFIKKAPIVIFPEGTTSNGRGLLKFMNVQIHVTGIKYVWTLAQLARILRIRKT-SKSVVDKCEFLS Botbo1 MEKYSAYRDAGTGLQPFLTPLGTLRAVVLLAITLLYLLLCARLALFVIGFWWIPVEAKKRGGDLIISNWVAWAELLWLAFRFNPV-FVKVSLLQMINATSIDEIRRRPVVVFPECTTSNGRALIRFADVNVFLMCVRYDTLLSSIAQLGKFKSIKGMGWEDKVSFLE Botci1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 MEKYSQFRDKGTAIAPFLPVLFCVRTPFVIAFSLLYFFVVLWLMLGIPGVWWVDLQGVKRGGTIVASSFTSPLDPLYLAGIFQPI-FTRITLFRAILLATLKQLISRIICVFPETTTTNGRGILPLCPSKIYPVNLRYTRLLSKLARLGRVKRV-GLGVETKIEFLK Coere1 MEKFSKWRDSGTGIQPFLQPLAGIRLTALATITVVDCALLAALALFILGFHWIDTKGLQKGGDIIIANHISYIDILYLVARYNPV-FIPVSMWSALRS-PLKAITEGPVVVFPENATSNGRALLQFLSVTIHIMAFKYPRLGCQ--QLSRLRMT-KLTAMDKRDFLA Conco1 MEKFSTWRDGGTGIQPFLPVIFLVKLIFIGLATLSHSL---RLNLFLLGFYNIGFKTLHKGGDIILSNYSSYLDIIYLYQKFQPI-FTISNEWD-LINNTLDELVKGPVVIFPEGVTSNGRGLLKFNPI-INLVILKYKKTIVQIGEVSRFRQC-SIGEVEKVAFLK Conpu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci MEKFSAYRDAGTGIQPFLTPLAVVRTMLVLVISLLYLVALGRTALFILGLFWIPVDTRKRGGDLIVSNWASWIEIVWLAIRFNPI-FVKASLWEMIMSTSLEEIRKRPLVVFPECTSSNARGLLRFADVNVHVLCVRYDTLATSIAQIGKLKRT-GKGWEDKTSLLE Croqu1 DQKFSKWRDGKAGVAPFVYPLATLRTSFLIMLALIYVLMICRIALYLLGFTRLPADTRHRSGDVVVINWSSYVDIIYLAHIYDPI-FIARSLLHLITTATLSEWVDQAVVVLPEATTSNNRAILRFVKLRFFCLGLKHDILLPTLLMVCKMKQTTGIGWSDKAGFLS CryneH991 MEKYSNWR-------PFLPPHSIVRGVLLAVLGTIHVLLTCRLALMLMGYWWISTESPRRGGDLVLANWTSYVEVLYLAFRHNPT-FLPYTLTSLLARTTLREARRRPVVLFPEGTTGNGRAILKFGEGIVWVKFFRHSSQLYTLAEVGKVRRVKGMGWAEKKAFLE Crypa2 MEKFSQFRDRGSGISPFIPHLFAFRLPLLLLYTAFYFILLTWGFLGIPWIIWGDLQGVKRGASVIAASFTSPVDAVYLAAVFDPI-FTRVGLFRTIWHATLAEIIARVVAVFPECATTNGLGILPFSPSKIFPVSIRYTRLLSRLARLGRNKRV-GLTVEDKAKFVE Debha1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi MEKFSNWRDGPTGIHPLLPPISIIRVPIILILTALLIIIIGRIILLCMGFIQLDEFTLSRSKDIIICNHSSYVDIIYLCYKFSPT-FAPLTLGRALENSDTNKLVEGPLVIFPEGTTSNGQGLLDISPISIHVIGLSYHLVCCQLSSLINTRRT-KITNNDKLSFIS Dmel ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi LEQFVKEGNFKTGIHPFMTQ-----KVIMVIDALVFLYCLLRIILFVCGIYSIQIT-----KRVIVSNHQSFLDIVIYRYLLNAV-FVELNLFQAIRRSKLELVKSNHIIYFVEGTTENGTIVLKSQLLPLTLSGLKY-GILSQFRNTLKVATS-SFSSYDKSEFVK Falba MSIPTAYTTAGTA-------------------------LAALLSLWIIGFWRIERQAYRRSATLILANHASYVDVLLLARAYAPAFFQITPTQAALHALPLAGVLAQPVVLFPEGCASNGRGLLAADPGPVGMLATRY-RLMDQASQLNRLRQL------------- Fomme1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 --------------------------------------------MAIPGIWWIDLQGVKRGGSVIVVNFSSPIDAIYLAAIFDPI-FTRVSLLGAVLAAEIKDLLAQVVAVFPECGTSNGKAILPFSPSHIFPVSIRYTDLLSRLARLSRVKRV-GLTMKDKASFVD Galma1 MEKFSAYRDPGTGIQPFLTPLGIVRTTLILFLALVYVTIIGRTILLILGIFWIQVENRKRGGDIIVSNWASWIDIVWLAIRFNPI-FVQVSLVSLINYTTLEELRRRPIIIFPECTTSNGRGLLRFCDVQVFIMSIRYDSLTTSVAQMGKLKRT-GLGWEDKSNFLQ Ganpr1 AEKFGRWRDPGTGIAPFLPI-----RLATLVLGILGVVIFFRSILFALGFWQIEERTLRKGGDLVVSNHCSYVDVLWLAHRYAPT-FVPLRYILVLLSSSLRSLLTHPICFFPEETTGNGRGLLRFGDGRVHVIGFRFDSLLLSLGRVVRLRQT-GLGWRDKEEFVQ Gloin1 -----------------------------------------------MGFYWIHSESLTKGGDVIVCNWTSYVEIFYLAFRFDPI-FTPISLWKAIWTTTLQELVNKPIVIFPEGTTSNGRALLKFNPIKIHIFTVRYEKLCCQMSQVGRLRKT-GLGMVEKKGFLD Hisca1 MEKFSQFRDRGSGIAPFLPILFCMRLPLLITAFVAYFCASLWVMLGIPGIWWIDLQGVKKGASVIASSFTSPIDALYLAAIFDPI-FTQISLVQAILRADIATLIKSPIVVFPECTTTNGKGILQMSPSRIFPVSLRYTNLLSKLARLGRVRRV-GLGAKDKQQFVK Klula1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MEKFSAYRPPLVLIQFFLGPPSSPRYHW----------VIGRTILCIIGLFRIPVLTRKRTGDIIVSNWVSWIELVWLAVRFNPL-FVKVSLLQMIRFTSLEDIRKKPIVVFPECTTSNGRGLLRFADVRVFVMCVRYDSLTTSIAHIGKIKQT-GMGWEDKVKLLQ Lenti61 MEKFSAFRDPGTGIQPFLRPVGLVKTVLLLALALVYFVLFSRLALFLAGLYWIPVDARKRGGDLIVSNWVSWVEILWLAFRFNPI-FLRVNLLSMLSSTTLEEVRSRPVVVFPECTTSNGRALLRFAEVKVFIMCVRYDRVASCMSQIGRVKRV-GMGWEDKAAFLN Malgl1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 MEKFSNWRDPSTGLAPFVYPLAFLRTISLVGLALNYLIILGRMALYLLGFTRLPADSSLRGGDVIVVNWCSYVDIIYLAYLFDPI-FIARSILSLITTSTLSEWVLQPVVVFPEATTSNNRAILRFVKLRFFCLGFKHEILLPGISNACKMKQTTKIGWADKAGFLS Mnele ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MEKFSRWRDQGTGIQPFLPPTGVVKLILVSILLLAFLLIFIRAILVLLGFFWIKNETLRRGGELIVSNWSSYIDILYLAFRYDPV-FTQITLWEALRQAPLLDFVKGPVVIFPEGTTTNNRAILKFVPIEIRIMALKYDRTCAQMGRMTRFRKL-GLNVKDKADFLD Mucci2 MEKYSRWRDASTGIQPFLPPQGIVKLVLIGLVALLYILIFLRIVLFLCGFFHIKTESIRKSGDVIVSNWTSYIDVLYLASRFNPV-FTIISFWEAIRLVTVQELSQGPVVVFAEGTTTNGRALLKFAPVNFQIMSFKYDKLCSQLGNVSKLRKT-NLSMSDKRDFVL Mydma ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 MEKFSQFRDRGSGISPFMPSIFLLRLPFFVLYTISYFLLLLWGFFALTGTWWSDLQGVKRGGTVIAANFTSPLDAVYLAAVWDCV-FVRLSLWQAISLATIAQLLKRAIAVFPECATTNGKGILPLSPSQIFPLSLRYTKLLARLARLGRAKRV-GLTVEDKKNFVK Orpsp11 --------------------IAIIRLICIFFIFIIYLIWETRLVLFYMGFNWIDSQTLTRGGDIIACNCQSYVEIIYFFSKYNPT-FVPVSFLEAIKLNTLKDVIKGPIIIFPEGTTTNGKGLLKFLPVTLHVYSIKYQKLCTKIGQVLRIRKT-GLGAKDKQEFLD Pench1 MERYSQFRDRGSGIAPFLPILFCFRLPLFIFVTLSYFLAALWCILGVPSIWWIDLQGVRKGGSVIASSFTSPIDAVYLAAIFDPI-FTRISLLQAILRADISTLVERPIVLFPECTTTNGRGILTLSNSKIFPVSLRYTTLLSKLARLSRVKRV-GLGVKEKQEFSR Phybl2 MEKYSRWRDAGTGIQPFLPPQGIVKLLIVAIITLAYVLLLLRLVLFFSGFFYIKTESLRKGGDIVVSNWTSYIDILYLACRWDPV-FTRVSLWQAIRLCTLKELAKGPVIVFPEGTPSNGRALLQFSPIAIHGMAFKYESICSQLSTMARLRKT-HLGMEDKRAFMN Picst3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 MEKFSAYRDPGTGIQPFLTPLAAIRTVLLIAATLLYVVLIARIVLLLSGLYWIPVQSRKRGGDIIVSNWVSWIELLWLAIKCNPI-FVEVSLLQMIRLTSLDDIRLRPVVVFPECTTSNGRGLLRFADVKVFVMCVRYDKLATTIAQIGKLKRT-GMGWEDKRAFLK Polpo MEKFSDWRDGPTGIAPLLPPLCIIRIPFIIVFTLLLVLVFGRSILFLFGFTFIDEASLSRSDDIIISNHTSYIDIIYLVYRFSPM-FAPLSLAGALKNAATEQLLAGPLVVFAEGTTSNGLGLLE-------------------LSSLTNCRRT-KITAHKKLSFVA Pucgr2 MEKFSTWRDPSTGLAPFVYPLALFRTALIVVLGLLFVIIFSRITLYLLGFTQLPSDTHRTSGDLVVCNWSSYVDILYLAYLYNPI-FISKGVLGMIFRTSLAQFLQRPLIIFPEGTTSNNRALLRCPKLKVFCLAIKHE---------------------------- Punst1 MEKYSAFRDPGTGIQPFLTPFGAIRALVLLAVSLASFVIFARTALFLSGIVWIPVEPRKRTGDIIVSNWVSWLEVLWLAFRFDPQ-FVRVSLLTMLRQTSLDDIRRRPIVVFPECTTSNGRGLLRFADVNVWVMCVRYDSLVTSIAQVGKMKRV-GMGWEDKAAFLE Rhior3 MEKYSRWRDAGTGIQPFLPPQGLIKLPVILLLSLCYVLILTRCILFFMGFFHIKTESIRKSGDIIISNWTSYVDILYLAYKFNPV-FTKISLWQAIRSVDIKELSLGPIVIFPEGTTTNGRALLKFVPL-FHLLSF--------LGHLSKLRKT-NLTMNDKRDFLV Rhoto1 AEKYSRWRDPATGVQPFLTPLGGLRTLLVVLLLLAQTVGIARLILAVLGVLWVNVEQLRKTGDLIVANSSSYVDLLYLAFRYNAS-FIRVGLLAAAWATSLSDALTGPVVLFPECTTSNNRALLKVPDLRIFVLAFKYPSLTSRLAQTARLKKVVGLGWVEKGAFLE Rozal11 MEKFNDWRDPGTGIHPFLPTLVLVRIPIIATLMVYWLIAFGKSILVLCGFLCVNCA---------------------FVKRYSCL-FLVLSFYDALICCLVENLSN---VLFIEGTTSNGRAILKPANIRLHLISIRYEGLCSQLSRLSKLRLLSVKSAEDKTAFLK Sacce1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 MEKYSAYRDPGTGIQPFLTPLGAVRFVLFLALVLVHVVITTRAILFVCGFFWIPVETRQRGGDIIVSNWVSWIELLWLAFQFNPI-FVTASLLEMVRST-LEDIRRRPIVVLPECTTSNGRGLLRFADVNVFVMCTRCDKLCATIAQIGKMKRV-GLGWEDKLAFLE Schpo1 MEKFTRWRDPGTGIAPFHPIVMILRVPLCIISVTLWFLSLSRLLLLCFGCLKLSKSSFVQGGDILAVNHSSPLDVLVLSCLYNCT-FAIISAQAYFWSCPLAKVAATVVILFPEGVCTNGRALCQFTPCRIFPLYIKY-LLTVSLSKLGRSRVV-KLGKSDKLSYLD Sorma MEKFSQFRDRGSGISPFMPSIFLLRLPFFILYTTTYFLLLLWGIFALTGTWWSDLQGVKRGGTVIAANFTSPLDAVYLAAVWDCV-FVKLSLWQAVTLATIAQLLKRAIAVFPECATTNGKGILPLSPSQIFPLSLRYTKLLARLARLGRAKRV-GLTVEDKKNFVK Sphar ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sporo1 MEKYSKWRDPSTGVAPFLYPLGVVRTLIVVLLLFADTISVSRLILVIFGIFNISVERLTKTGDLIVANSSTYIDLLYLSFRHNAT-FLRVSLLTAVWENTLEQAVRGPVVVFPECTTSNNRALLRFPALKIFVLTFKYSSLLSVVASTGRFKRLGSLGWKEKEGFLE Stehi1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 MEKFSKWRDPATGIQPFLPPHSLVRGILLGIVAILHILITTRLSLFLMGYWSIPLDTPKRTGDLIISNWTSYVDIIYLTYKFNPT-FLPLSLFSLLFQTSLQDARKGPIVLLPECTTSNGRALLRFPEGLTWIIYLRHSSLLFTLAETGKVRRVKGMGWVEKEGFLE Trire2 MEKYSQFRDRATGIAPFLPVLFLVRLPIFLTYALGYFLIALWGLMAIPGIWWIDLQGVKRGGSVIAANFTSPIDAVYLAAVFDPV-FTKIGLLSAIMMADLKDLIKRVIAVFPECGTTNGKAILPFSPSHIFPVSLRYTTLLSRLARLSRVKRV-GLTMKDKAAFVK Umbra1 MEKYSRWRDAGTGIQPFLPPLAIVRVAVVFVLLGLYVLILARMALFVIGFYIIHSESVRRGGDVIIVNSSSYIDILYLTFQFSPL-FTFITAQEAIAQCSLKEASKGPIVVFPEGTTSNGRALLKFIPLKIHILALKYEKLCCQLGGIARLRKT-SLGIRDKIEFLD Ustma22 AEKYSRFRDPGTGIQVFLTPLGLVRSLLALVGWLIYVCVGLRLVLFALGFVRLPLDDNKRDRDLVLANHSSWIDLLIVAYLYPGVKFLILGLSQAIWFVSIDRAISCALVMFPEGTTCNNRALLSMSVLTTHLVTLKYSRLVFLISNLARLKTT-TIHWSAKADFLH Walse1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3828.fasta_al_trimmed; alignment length = 115] Allma1 ------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------- Aspfu1 TVSIHQILFLRSVYPRATFLPVRAYNYP--VRQSRHPKVCDYINDASIAVGTEILK-GTITAVSIIISSPLERYAFDLSDLEAQFRACLARLAIEVRELPPAGTVPVRRVEAGEL Aurde31 EVAIHTLLFVRGVYPENLFVRRRKYNTA--VFQARHPALRDYISRACASVREELLL-GTVARLAVVISDPLERFVFDVAALAQRFRGFMLKLALELTDVPTAAERYVSAIDTQIF Batde5 ------------------------------------------------------------------------------------------------------------------- Botbo1 EVAIHTILYVRQVYPPDLFVRRKRYDAP--VYQSRHPALNEYIAGAVKAVGEELVL-GNVERVVVVIKDPLERFVFSLRSLPQFFRSFLIKLNLELRDAPSAAVHVVRAVETGVI Botci1 --AVHNGVTPRHLRHLVCCCHTPTVQVPSNVPQNRHPELCAYINSCVSAITPHLQA-GTINTVSIVIYSILERYIFNLSDVNA------IRNIMEMKENAPIGSTAIRAVEVGDF Caeel ------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------- Capow EVAIHMILYARQLYPMESFERRKKFNVP--VYMNRHPELNRYILDIVSSLRPWMEK-RLVTRVAVNVVNILERFVFEV-DIELMLRAVLIKIS-VLAKETQASLHPLKSVHTGLL Catan2 ------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------- CocheC53 TAYTHTLLYLRTLYPRASFVQSRFHNAS--VYQSRHPLVCEWITDAIAAVREELLN-GSVARVAIVVFSIMERYMFDVS-LSEQFRAALIALTMELKDDPPIGVTPIRSVQSG-V Coere1 EVYIHGILYARGIYPQSLFEDQYAYGIP--VKASRHPELNGYIINVVAAIKSELEKEGPLGDVMVNIVDTIEAFVLELSDIE--LRAAIIRMS-----SAPSQLVPLASVESAEL Conco1 ------------------------------------------------------------------------------------------------------------------- Conpu1 ------------------------------------------------------------------------------------------------------------------- Copci EVAIHTILYVRQVYPPDLFVRRKKYETP--VYQSRHPALNEYISGAVKAVSDEMAQ-GTVEKVVVVIKNPLERFIFSIDSLVQYFRSFLIKLC-----YPSGTAYDARNV----- Croqu1 EVAFHNILYTRKVYPADLFEQRKKYEVP--VFVSRHPLLTSYISGVVSQSAEEISK-GLVNKLVLAIQDPLEHYVFDLQDAQVHLRAFLIKINLELNDKEPLSLIPLKSQGLGMI CryneH991 EISLHTILCIRQIYPPTTFTRRRAHGVP--VYQSRHPTVRSYISQVIASVSQEINE-GRLKRMTVVIKSPVERMIFDIGELGLMLRGFLIKLSIETNDAPSSNLLSVKAIETGVI Crypa2 TVSIHTILYNRNIYPRDTFLSAKAFNLP--VHQSRHPKVCSWINDAVDAVMAQLAK-GTVERVAVVIHSVLERWMFDVSDVDEQLRGAARRLAVELRDRAPIGTIPIRTIETGPL Debha1 ------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------- Dmel EVLVNHILYVRGIYPSHIFKMKRMYNSP--IYVSIFPPLNNYLAGVLKSAQELLRR-RELQCLELIVYQKLESYKMQLEEFEQNMRSVIYKISLHTTQFIRFSLLPLARVDDLGL Enthi ------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------- Fomme1 EVALHAILCVRQVYPFEIFERRVKFGIP--VFRCTDRTINEYVSEVVKAIGEELVE-DAVERIIISIHQPLEKFIFSFDTVQRQMRSMLMKLNMQLREKYRISANLLHVIKTGYL Fusgr1 TLTLHTLLYHRGLYPATTFLTARALNLP--VHQSRHPGLCTWINDAVSSVAAQLRK-GTVRRIAIVMHAVLERWVFDVEDVNEALRGALRRISVELRDSAPIGTKP--STTNRHL Galma1 EVAIHTILYVRQVYPADIFVRRKKYDCP--VFQSRHPTLNEYISGVVKAVADELVH-GKVDKVVVIIKDALERFIFSVESLTQYFRSFLIKLSIELKDAPTHSLHMIRAVNTGII Ganpr1 ------------------------------------------------------------------------------------------------------------------- Gloin1 ------------------------------------------------------------------------------------------------------------------- Hisca1 AVSIHQILYPRAVYPQPTFLPVRHFNHP-----------------------------------------------------------------VRL------------------- Klula1 ------------------------------------------------------------------------------------------------------------------- Lacbi2 EVAIHTILYVRQIYPAELFVRRKKYETP--VFQSRHPALNDYISGAAKAVGDELAH-GTVDKVVVVIKDALERFIFSVESLIQYFRSFLVKLSLELKDAPSVSLHMIRAVNTGII Lenti61 EVAIHTILYVRQVYPAELFVRRRKYDTP--VFQSRHPALNEYIAGAVRAITDELAL-GTLDKVVMVIKTPLERFIFAVRSLGQYFRSFLVKLNIELQDAPTATLHMVRAVDTGII Malgl1 ------------------------------------------------------------------------------------------------------------------- Mellp23 EVAFHNILYVRGVYPSDLFESCKKYDVP--IFRSRHVLLTSYISGVVSQVVEEISK-GFVNKLILAIQDPLEHFVFDFQDAHVHLRAFLMKINLELNDKEPVSLIPFKSEGLGMI Mnele ------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------- Morel2 EVAFHMIIFVRGIYPPELFESTQKYSCP--IKTARHPGLKAYIQQIVHSLRTELLK-DTIHRICVVTLDPVDRFVFEMSDLETMLRAMLLKVSVEMKNPGPEAIIPVKTIDVADI Mucci2 ETWLHQLLFKCELYPKAIFKQQKKFQVP--VHIALHPQVQAYIADFVQSCQPLLEK-GDVRFIALTVMEPVEKFVLEIRDLEQYLRACLIKLNIEKIQHPHQQIKPLKSVELDLI Mydma EVAINTILYVRNIYPRGIFERYQKYNMA--VMMSKHPDVNLYISNVLCSMKPLIHK-NELEKLVIQINNPLDKFCFDLKELELYLRSFLLKLMIEDED-----ITPIRSCDTQLF Neucr2 VVAIHNILYYRGIYPQPTFLSARAYNLP--VHQNRHPKVCAWIRDAVKAVAAQIAE-GRVSRIAVVIHSVLERWMFDVSDLDEQLRGALRRMAVELRDLAPIGTSPIRSVEAGAL Orpsp11 ------------------------------------------------------------------------------------------------------------------- Pench1 TVSVHQILFLRSVYPRATFLPVRAYNYP--VRQSRHPKVCDYINDASIAVGTEILK-GTITAVSIIISSPLERYAFDLSDLEAQFRACLARLAIEVRELPPAGTVPVRRVEAGEL Phybl2 ---------------------------------MTHPGVNQYVADFVSLIRPILTK-GSCRSVSLVVLSPLERFVFEVECVQQHIRACLLKMHAEIHSFPPDTFVTLKTIQMDLF Picst3 ------------------------------------------------------------------------------------------------------------------- Plicr1 EVAIHTILYVRQIYPADLFVRRKKYDTP--VFQSRHPALNEYISGAVKAVGAELAL-GNVDKVVVLIKDPLERFIFAIQSLQQYFRSFLIKLNIELQDAPEAALHFVRAVDTGII Polpo ------------------------------------------------------------------------------------------------------------------- Pucgr2 EVAFNQILYLRNVYPADLFEQRKKFNVE--VMASRHPVLTSYIGEVISQSMEEVVK-GLAKKLILAVQDPREHFVFNLQDAELHIRAFLIKLNLELNDKEPLSLIPLKSQGLGMI Punst1 EVAIHTILYVRQVYPADLFVRRKKYDTP--VYQSRHPVLNEYISGAMRAVGDEIIS-GTIDKVILVIKDALERFIFSIETLGQYFRSFLIKLSLECKEVPGASVHLVRAVDTGIV Rhior3 -------------------------------------------------------M-AQVKFINLTVMSTIEKFVFEINDIEYHLRACLLKLNIETLQYPSTTILPIKSMTLDLF Rhoto1 EVAFHTLLYIRQVYPAQLFAEVKKYNIP--IWQSRHPMLNEYLGRILECIQGEMEK-GTIRRVIFVVKDPLERFIFEFEDVEELLRACLLKLNVELKDPPPESISPLEAIRLGMI Rozal11 ------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------- Salro QASVYAILATRGVYPAHLFEKRLVFGVP--TYWPRAEALEDYVRNGVTFVQSVLQQ-GKLFNFFVTILNPVERFIFDIDVLERQFRSVLVKLSCETEA-----MQVLKRVAAHPL Schco3 EVAIHTILYVRQIYPADLFVRRKKYDTP--VFQSRHPGLNEYISGAVKAVGEELVQ-GTVAKVVVVIKDPLERFVFALEILSQYFRSFLVKLNLELKDAPTAALHVVRAVNTGII Schpo1 LVSIHCILYARRLYPQDLFIKARKYNTI--VWQSRHPILCEYIEEVVQSCIEELQT-GSVHQVALSIINEEERYVFSTD-----MRASLIQLLVTLKDPRPK-TIPVRNVDIGPM Sorma VVAIHNILYYRGIYPQPTFLSARAYNLP--VHQNRHPKVCSWIRDAVKAVAAQIAE-GRVSRIAVVIHSVLERWMFDISDLDEQLRGALRRTAVELRDLAPIGTTPIRSVEAGAL Sphar ------------------------------------------------------------------------------------------------------------------- Spipu1 --------------------------------MSRHPVLNGYIRDVLAGIKPDLQK-GVVSKVYLAIHDVVEKFTFQIRDVEAYLRSFLLKIAVELAGPTPTSLIPLKTMDAGLL Sporo1 ------------------------------------------------------------------------------------------------------------------- Stehi1 EVSIHSILYIREVYPAELFVRRKKYDTP--VYQSRHPGLNEYISGAIKGVFNELLQ-NNVEKVIIVIKNPLERFIFAVQPLTQLFRSFLLKLNIESPEAPSDPLHLLRAIETGII Tapde11 VVCLHTICYYRNLYDRTYFSLARVYSCP--VQRCKHPILVEYINSVVSSIAEELRK-CLVERINVVIMSPLERFVFDVSQLDAQFRAAIMKLAIELR--RNKSTIPLRRIGFGPI Thetr ------------------------------------------------------------------------------------------------------------------- Treme1 EIVIHTILCIRSIYPPHTFTRRKAHSVP--VYQSRHPQVRQYIAEVCSLIGKELER-GNARRVTLVVKDPLERFIIDFGELSLLLRAFVIRLNVETSDEPSSNLLHVKAVETGVI Trire2 TIAIHSLLYHRGLYPEQSFLAARAFNLA--VRQSRHPGLCAWINDAVDAVSARLRT-GSVSRIAVVVHGVRERWLFDVDDIHEALRAALQRLAVELREEAPIGTKPIRSVRAKPL Umbra1 EVAIHQILYVRGLYPKEIFATRQKYNTP--VHMSRHPDINQYINHVVAACKDGIHQ-RNVKAVSVEVFDPVERFVFELNDLELQLRAFLLRIHVDMERV-PASLVPLKSVDTGVL Ustma22 EVAFHTILCMRSVYPYDVFARRKKYSHP--CYQSRHPGLNEYISRVLAALRIEIEK-STVRKVILVIRPAYERFVFNLDELEMMFRGFMQKLMLEMVDMPPLGIRPIKTLDSGVI Walse1 EISIHTILNIRQVYPQFTFERKQKWGAI--VYKSRVPAVQSYITSLVESVIEQIKQ-DKVENIIVIIKNPFEKFIFRIDQVGVYARSILVRLSLELRQ-----IIPVRAIDTGIL Zygro1 ------------------------------------------------------------------------------------------------------------------- [Cluster3833.fasta_al_trimmed; alignment length = 74] Allma1 ----MPSPHHASVAAQVLSVDKELKPHFLRRTLADGA-TLTIHYEASSVKLLRTSVNGVFEQLVSVVRTMIA-F Ashgo11 LHVPFESARLADIAARALAPDPLLRPEELSVSFSDGA-SLNIKLAAIDARVLRVATNSIFEALKTVVETADE-L Aspfu1 -------------------------------------------------------------------------- Aurde31 LRVPFQSAEHARIALQVVQVDRELQPDAVKRSLLDGD-VLVVTFTTLTVRLARLTLNAFLDNLDLVIRTLSD-F Batde5 LNIPFGSSKFADVAAQVLSVDNELQQSMVQRSITHNS-ELIVAFTSPSLKMLRTSVSSFFDMASLVARTIAE-F Botbo1 IRIPFLTAEHATIAKRVIDVDRELQPHVVKRTLVEGE-TLVCTFETFTVRLARLTTNAFLENVDLVIRTIGE-F Botci1 -------------------------------------------------------------------------- Caeel -------------------------------------------------------------------------- Canalb1 LNIPFETFNQAAIAKNTLSPDPILRSDELTIDYTDSN-NLKVKFSGVSDRVIRVAISNMIDNIKTIIECMDE-F Cangl LHVPFETARDALIAQRVLQPDPILRPEDFQVEYAKAT-VLDIHFKAIDDRVLRTYASEVVSKLRYIIRYTDH-I Capow -------------------------------------------------------------------------- Catan2 VRVPFPSADLASIAARVLTVDKPLKPHEAYATYVDGN-VFEMVVHANSIRMLRTTVNANLEQLVSVTNTMAE-L Cioin -------------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------------- Coere1 LRIPFKDAILADIAKQSLEVDPVLSGDKVQLTVVDGR-YLIVTCNGDTLRMVRVSINGFMDSLILVTRTLEA-F Conco1 VSVPFETTEFAKVAYEAIRVEAEVKPKLISTKFLNEN-NLIITFSSNSLKMIRLSVNNRLEMLALISKTIHH-F Conpu1 -------------------------------------------------------------------------- Copci ISVPFISEKHATIAKRAIEVDAELQPQAVKRTLIEGN-QLIGTFETLTVRLARLTVNAFLENVDLVVRTIEN-F Croqu1 -------------------------------------------------------------------------- CryneH991 LKIPFHTSEHAVIARRALDVDREQNGSLVRREMVEGD-ILVVNYATTSVRLLRLSTNSFLSSADLVLRTMSS-F Crypa2 -------------------------------------------------------------------------- Debha1 INIPFESEKQALIACNSLSPDLILRSTELSVSCSSDR-NLICEFSGSSDRVIRVAISSVIDNLKTIIECMDE-F Dekbr2 SAFPFLSSEQAVIARKSLEPDPILKPEELEALFVDKN-VLKIILRSSSDRMIRIIANNFMDNIKTVIECLEN-F Dicdi -------------------------------------------------------------------------- Dmel IRVPFETPRLAEIAYKVLGVDQEPRRNFVKKTLLEND-VLVVHFQSDQVKSLRTAITSFFECLLLCQDTINQ-F Enthi -------------------------------------------------------------------------- Falba TRIPFPTARQAEIVLRSVNADPEPVASVLNRTMVQDN-VLLITIRSESLKTIRSCMSSMLDMIQLSIETQAR-F Fomme1 VRIPFASPKHASVAKQAIEVDSELQPQAVKRSLVEHD-ELVATFSCLTIRLARLTVNSFLENVELVIRTLGE-F Fusgr1 -------------------------------------------------------------------------- Galma1 VEIPLASNKHALIVKQVIEVDAELQPHAVKRELVQDE-KLIATFHTLTVRLARLTLNAFLENVDLVVRTIEV-F Ganpr1 LSIPYPTPRHAEIVRQVLSVDKEHSQDMIKRRLSEGN-VLVAEFDAWDVKKLRTTVGFFAELAALATETIVE-F Gloin1 LTIPFPSSRLANIAERALNVDKELKGDQVKRIITDDD-KLIVSFDCASVKMLRVSVNSLFDMIIMITKTMDA-F Hisca1 -------------------------------------------------------------------------- Klula1 LEIPFESIKQADVARKVLLPDPIMKPEDFQVTYTQDT-KLICDFESVDERILRVGVNSVIESIKTIVETIDE-L Lacbi2 VKIPLASSKHALIAKQVIEVDPELQPQAVKRTLVDDN-LLIATFQTLTVRLARLTLNAFLENVDLVIRTIEH-F Lenti61 MRIPFASHKHANIAKQVIEVDRELQPDVVKRTLVEGN-ELIATFTTLTVRLARLTSNAFLENVDLVVRTIGE-F Malgl1 -MIPCPSREVATTIQQVICVDKELRPHDVEKSLDDGRADLHVTMRATTLRHLRLSLNSFLDDTALIVRTMDA-L Mellp23 -------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------- Morel2 LQIPLPSPRLAKIAADVLDVDKDLKPEVSRRLITQDN-ILTLDFQTSTLKLLRTVVNSSLEMVQMVVSTMAS-F Mucci2 IEIPFPNERLASIAQQAMNVDKELKTDQVNRVIAKDN-LLHVQFECYNTKMLRVAVNSFLEYLTMVTRTLEEDF Mydma -------------------------------------------------------------------------- Neucr2 -------------------------------------------------------------------------- Orpsp11 -------------------------------------------------------------------------- Pench1 -------------------------------------------------------------------------- Phybl2 LEIPFPNERLAIIAKRVLSVDKELKTDQVKRTVTAGN-TLTVSFECTSTKMLRVAVNSFLEMLTMVTKTMDQ-F Picst3 LSVPFENEKQATIACKSLSPDPILKADELVVTYTEGS-SLVLKFEGISDRVIRVAISNFIDNLKTVVECMDE-F Plicr1 VRIPFASTHHATIAKQAIEVDKELQAQSVKRTLVEDD-VLVATFQTLTIRLSRLTVNGFLENVDLIARTLGE-F Polpo -------------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------------- Punst1 -------------------------------------------------------------------------- Rhior3 LEIPLTNERLATIAARVLDVDKELKVDQVKRTITEGN-ILKVRFECYTTKMLRVSVNSFLEYLTMVTRTMDA-F Rhoto1 LSIPFPNADNATLVKRVIEVDRVLRPSELSRELVEGS-DLKATLRAATVAQARVALDHLFSDIQLVVQTMHK-F Rozal11 -------------------------------------------------------------------------- Sacce1 LKIPFETERQATIATKVLSPDPILKPQDFQVDYSEKN-VMLVQFRSIDDRVLRVGVSSIIDSIKTIVEAMDV-L Salro LRVPFASAQDASIALNTLVVDKEPKPDICRRTMVQDN-TLLVTFEATELRTLRVASAWFMDMLQLTCETIDA-F Schco3 LRIPFVSEKHAKIAKQTLEVDRELQPQSVKRILVDGR-YLVTTYKTLTVRLARLTANSFLENVDLVVRTLGE-F Schpo1 VKVPLASRVDAERCLQVLAPDRELKEELVQRNLVDDN-YLVVNYSCSSARMTRVTVNSLFENLYLIIDTMHE-L Sorma -------------------------------------------------------------------------- Sphar -------------------------------------------------------------------------- Spipu1 INIPFPDTRLATIAQQVLSVDKELKAAECQKEMVEGT-SLVVTIRGVSVRVVRTAVSSFLDFAGLVVNTMEA-F Sporo1 -------------------------------------------------------------------------- Stehi1 IRIPFATNKHATIAKQVIEVDRELQPHAVKRDLVEGD-VLIATFSTLTVRLARLTLNAFLESVDLIIRTIGE-F Tapde11 -------------------------------------------------------------------------- Thetr CRIPVGSKRRADIVLGAVGVDAELRPEVVSRQWVDDDGVLAVTVASDELRAVRVSCTSVLDHVALAIRTLAA-F Treme1 LKIPFYTSQHAQIAKKVLQVDKEQNAQLVERQLVEEN-ILVVTYKTATVRLLRLATNSFLSSAELISRAMSE-F Trire2 -------------------------------------------------------------------------- Umbra1 LEIPFPTPRLASIAQKTLSVDKELKVDQVKRILANGD-KLIVDFECTSVKMLRVSATSFFEMLTMVTSTMEQ-F Ustma22 -------------------------------------------------------------------------- Walse1 LSSISTSCQHPDIVKNVLDVDKELKPDFVSRSIVQGS-NLITTFEAVSLRTLRTSTNAFLDNLKLVIQAIDT-F Zygro1 LTIPFPNDRYSEVAVKVLRPDPILRPEDFQVEYSKGN-LLEIDFKSVDDRVLRVGVSSVIDSVKTIVETIDE-L [Cluster3834.fasta_al_trimmed; alignment length = 177] Allma1 RAVVFDLGGVCVSPGHAIARYEELGLPRQYIGVTLGPFQRFERGEIHLFQADLHAWVAKKDIDARALFTRMMREAVPLMVQAIEHLKAAGKYKIGCITNDY-LMSLFDVVSSSRVGIRKPDPRIYHLLFERLDVA-PRECVFLDDLVNIRAAQQVGMTAILVA--SAQAIADLEGVL Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 VGLLFDIGGVCVSPFQAILDYEANNIPKGWVNFSIGSWHRLERGEIKLFNRDLRN-LQK-KIDAEWLFWEMMRVSDPYMYPALQKLKASGQFIIGALSNTVGVKSQFDFISSAHTGLRKPDPKIYAAALREMGVE-PSDVVFLDDIGNLKAAKNAGLRTIKVNLGRTDAIRELEKIT Aurde31 KAVIFDIGGVVVSPFLGIAAYEAHGLPRNYINCLIGAYQRYERGELGLWGVELNNYSAK-RIAARDLFGQMMRQADQGMVAAIKRIRARG-LRVIALTNNYRVRELFDWVDSSMEGLRKPDPKFFLLACERNGIR-PEEAVFLDDIGNLKAAASLGMSTIHVPLGRSGALKTLEERL Batde5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 RAVFFDIGGVVVSPLLAINAYEEKNLPRDYLNVIIGSWQRFERGEMEIFGRELSDYCAS-KIDGRELFGRMMRESDPLIVEAIRCLRASGKYRVVALTNNFSMVEMFDFVDSSSVGMRKPEPGFYLHGCARNGVR-PDEVVFLDDLGNLKAASKLGMHTIHVPIGGSGALRKLEAIL Botci1 LSCPLE-----VSPMQAILDFESNNIPPGWVNYALGFWHRLERGELELFTSDLHN-VRE-KIDGESLFWSMMDNSDPWMYPCLQKLKASKKYTLAGLSNTVFIPEIFDFVSSAHVHMRKPSPEIYALTLRTLPLS-PSDILFLDDIGNLKAAKTAGFRTLKVNLGRAEAVEELENIT Caeel KAVVYDFGGV-------LLSYESLGLPDDAVH---GPDRSLFLGTLTVYGNKLTD------VVIKPFTECLRGENHKNMQKTVEILHKKG-FKTAMLTNNM-----FDVVESCLEHLMKPDARFYHLVEKRLGVK-PEEIVFLDDLHNIEAAEKLGWNTILVE--DIKAIHELEGFT Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 TTIVFDLGGVCVSPVSAIRDYEHLGLPPRFIGVSVGPFQRFERGELTYFQAHLTSWRTS-RIDARDLFERMVRRSEREMVWAIEKLKESGKFKLGCITNDF-LMSLFDVVSSSTEGIRKPDPRIFKIACQRLRVTDPRQVLFLDDLKNIEGAQRLGMRTIWVK--DVKAVGELGNVV Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 KAILFDIGGVVVSPFQAILDYEENKIPIGYINYAIGAWQLIERGEVELFKQQLSR-LAK-KIDAKRLFWRMMKISDPYMYPALRKLGESGKFVLGAFSNNVDITSFFDFLGSAAVGVRKPDPEAYKLAVKEMEVT-AGDTLFLDDIGNLKFAKKTGLRTIKVNLGKTEAVMELEEAV Coere1 RAVIFDIGGVVVSPFIAISVYEEHRLPANYINVALGAFQQYERGEINYWTDELNEYLQR-RINGSVLFAQMMELANDCVVELIRWLRSRG-YRVAALTNNF-LVGLFDFVESSVVGLRKPDPKFYLHVCNLLEIR-PSEAIFLDDIGNLRAAKALGMTPIQVEIDKEDAVKAVKNII Conco1 KAIIFDLGGVCLSPLNSIRDYEENNIPKEFINVIIGPFQKLERGEVDYFHRLLNLYLKL----------------------------------------------------------KN---------------------------------------------------------- Conpu1 KAVIFDIGGVVCSPFVAIAQYEEKGLPPNYLNVSIGAWQKFERGQLPLFGADLSDYCKR-KVDGRELFGRMMHQSDMHVLRAMERLRASGRWKLIALTNNFHLRDLFDFCDSSTLGVRKPDPEIYLIACNRNGIK-PSEAIFLDDIGNLKTARKLGMETIHVPIGRTHAVKQLESKL Copci KAVIFDIGGVVMSPFVAIAAYEELGLPENYINTTMGAWQKFERGEIDIFSRDLSDYCER-KVNGRELFGAMMKASDPYIRAAILRIRAEGKHKVIALTNNFHLLELFDFCDSSALGMRKPEPEFYLAACKRNGIE-PKDAIFLDDIGNLKAARELGMDTIHVQIGKTEAVKELERRI Croqu1 KAIIFDIGGVVASPLIGVSKFEQLGLPLNYLNVAMGAFQQLETGRVQFFGNEMSDHCQR-NVDGKELWKTMMSEANDPIIQVIRRLKASGRYKVAALTNNFEIKNLFDFIESSQVGMRKPDPLFYRYALDRLGVE-PHAAVFLDDIGNLKAARALGIKTIRVGIHDVPAIRELQKFV CryneH991 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 KVILFDIGGVVLSPFQSILDYESLGIPPGWVNYSIGYWHRLETGRIPLFSEDLHS-QRA-KLDAEWLFNDMMATADPWMFPALQKLQASGKYILAALSNTIPVRGLFDFISSAHVGMRKPDPRVYQYALQQVGIQ-AGDVVFLDDIGNLKGGKKAGFRTVKVDLGRAQAVDELERIT Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 KAVIFDIGGVVVSPLLAISAFEERGLPRNYINCAIGAWQRFERGELALFSRELSDYCKA-RIDGRDLFGWMMRESDENMVEAIRRIRAVNRWRVIALTNNYKLRELFDFCDSSSLGMRKPEPEFYLLACRRNGVQ-PTECVFLDDLGNLKVARQLGMKTIRVPIGGSMALRELELEL Fusgr1 KVLLFDIGGVCVSPFQAILDYESLGIPPGWVNYSIGFWHRLEKGEIPMFSQDLHD-EQG-KIDAEWLFHEMMTVSDPWMYPALKKLKENGQFILAALSNTVPVRQIFDFVSSAHVGIRKPDPAMYQLALARVGVK-PDEVAFLDDIGNLKAARKQGLRTIKVNLGRAEAVDELERVT Galma1 KAVIFDIGGVVMSPFIAIAAFERLGLPVNYINCSIGAWQKFERGEIELFGNDLSDYCDR-KIDGRELFGAMMREADPHIRLAILRLRAAGQHKIIALTNNFHLTDLFDFCDSSSLGMRKPEAGFYLLACERNSIK-PWEAVFLDDIGNLKAANALGMDTIKVLIGRTEAVKELEKKV Ganpr1 KGVLFDIGGVVTSPIQGIMEYEKHGIPRGYINFCIGAWDRLERGELKVLEKDVGKYYGS-RINGEECFRTMNESADQKMVKAIDRLRAAG-LRVGALTNNSHIPSLFHFVESAIIGHRKPHPEAFLIACKELGVE-PRETVFLDDIGNLKGAQQLGMTTIQVKIGESEAIRALEKYV Gloin1 KAIIFDIGGVCVSPFQGIAKYEQFNLPKNYINVAIGAFQRLERGELSIFGVELSDYLRSRKIDGKKLFRMMMSEANPVVYNAIKKLR-VNKFKIAALTNNFEFKKLFDYIESSVIGLRKPDPKIFLYACEKLGVK-PNEVIFLDDIGNLKAARDLGMKTI----------------- Hisca1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 KAVIFDIGGVVMSPFIAIAAYEEQGLPENYINCSIGSWQKFERGEIELFGRDLSDYCER-KVNGRELFGAMMREADPHIREAIVRIRAARKHKVIALTNNFHLRELFDFCDSSALGTRKPEAEFYLLACARNQIK-PSEAIFLDDIGNLKAAKKLGMDTIRE--------------- Lenti61 KAVIFDVGGVVCSPLIAIAAYEEHGIPHNYINCAIGAWQRFERGEMSLFGRELSDYCKR-KIDGRELFGRMMRESDELIVEAIRRIRAAGRWRVIALTNNFRLRALFDFCDSSTLGMRKPEPGIYLLACERNGIK-PFEAVFLDDLGNLKAAQALGMETIQVAIGGAEALKKLEAKL Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 RVVIFDIGGVVASPLIGIAKFEQNALPHDYLNVAMGAFQLLETGRIQLFGQEMSDHCLR-TVDGKELWRMMMGEANTPIIQVIKRLKGSGSYKVAALTNNFEIKQLFDFIESSQVGMRKPDPKFFQYALNRLGAE-PHRTVFLDDIGNLKAAQALGIKTIRVGIYDVPAIRALQKYV Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 RAVLFDIGGVVVSPFQGIADFEQHNLPVNYLNVAIGAFQRLERGEVDLFSDQLSDYAEL-RVDGRALFHQMMSKANPCMVEAIAALRKAG-YTVAALTNNFQLKTLFDFIESAILGLRKPDPAIYKKAAEIVGFK-SEEIVFLDDIGNLKAAQNEGWTTIRVLLGKPQAIEQLESTL Mucci2 KAVIFDIGGVCVSPMAGIHRFEQHGLPRNYINVAIGAFQKLERGEIKLFGLQLSHYLAK-SVDGKELFTTMMAETDPHIFLAIEKLKASGKFTIAALTNNFKLRALFDFIESRLIGLRKPDPKIYHYACKEIGIQ-PNEAIFLDDIGNLRSANKLGMNTIQVKMGHSEAVKQLEALT Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 KVILFDIGGVCVSPFQSILNYERHSIPPGWINHSIGFWHRLETGSIPMFNRDLHNHQQA-KIDGEWLFHDMMEHADPWMFPALQKLKEDGRFVVAALSNTVPLRQLFDFISSAHVGLRKPDPRIYQLALEKVGVR-PEDVVFLDDIGNLKAARKAGFRTIKVGLGKAEAVDELENVT Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 ----YNLGGVCVSPMAGIRLYERYGLPTNYINVAIGAFQKLERGEIKLFGDQLSNYLEK-TINGKDLFTTMMKETDQKVFTAIRKLRESGQFRVAALTNNFTLKKMFEFIESRLVGLRKPDPKFYLHACKLLNVN-PTECIFLDDIGNLSSAKKLGMATIRKLIRK----------- Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 KAVIFDIGGVVLSPFIAIAEYEAHNIPHNYLNCSIGAWQRFERGELPLFGRDLSDYCKR-KVDGRELFGAMMRDGDEHILKAIHRIRAAGNHKIIALTNNFRLRALFDFCDSSALGMRKPDPAFYLLACQRNGVT-PSEAVFLDDIGNLKAAKELGMETIHVPLGGTEAVRQLERKL Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 TTVIFDVGGVVVSPLLGVNKFEAEGLPADYLNVAIGAFQKLEVGALQLFGDQMSDFCSK-TVDGKQLWKQMMVEANLPIIKLIKRLRESGKYRVAALTNNFEIKDLFHFIESSQVGLRKPDPKFFEYALKLLNVRGPKEVVFFDDIGNLKAAEKLGINTIKVGINDVPALEQLQKYL Punst1 KAVIFDVGGVVCSPLIAIAEYEQHGLPNNYINCSIGAWQKFERGELQLFGRELSDYCAR-RIDGRELFGRMMRGSDAVVVEAIRRIRASGKYRVIALTNNYRLRALFDFCDSSALGMRKPEPEFYLLACKRNGIR-PQEAIFLDDLGNLKAAKELGMDTIHVPIGGSQAIKKLEFKL Rhior3 -----------------------------------------------M-------------VDGEILFKTMMAEGDPFIYSALERLKASGLYTLAALTNNFKLRKLFDFIESRLVGLRKPDPKIFCYACDLIGIQ-PNEAIFLDDIGNLKAAKQLGMTTIRKKCEDGHKRRSQAA-- Rhoto1 RAVIFDIGGVVVSPVEAISRAELWNLPKHWINAAIGPFQRFERGEMGQFGARLGDYCKR-AIDGKELWGLMMDPADPVVVEAINRLRASQRYKVAALTNNFMMKGLFDYIESCVEGLRKPDPKSFRLALDILGVE-AHETVFLDDIGNLAAAKKLGIKTIRVKHGKSEAIRELEETL Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 KAVIFDIGGVVASPFVAIAAYEKHKIPENYLNCSIGAWQRFERGELPLWSEDLSDYCRR-KIDARELFGEMMRESDPHIVRAIRRIRETGRYKVIALTNNYDLVDLFDFCDSSKLGMRKPEPQFYLLACKRNGIK-PEEAIFLDDIGNLKVAKQLGMETIHVPIGGTDAVRQLERRL Schpo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma KVILFDIGGVCVSPFQSILNYERHSIPPGWINHSIGFWHRLETGSIPMFTRDLHN-QQA-AIDGEWLFHDMMEHADPWMFPTLKKLKEDGRFVVAALSNTVPLRQLFDFVSSAHVGLRKPDPRIYQLALEKVGVR-AEDVVFLDDIGNLKAAKKTGFRTIKVGLGKAEAVDELEGVT Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 KAVFFDIGGVCVSPLEGIRKFEERGIPENYLNVAIGAFQKLERGELPLFGQECSDYLKS-KVDGKELFTFMMQEADPIVINAIRKLRESGRFKIAALTNNFELVQLFHYIESSVVGLRKPDPEIFRYACTKMGVE-PKHAILLDDIGNLKSAREVGLATIRVVVGNSEAIKQLESLT Sporo1 KAVIFDIGGVVVSPVQAISRAELWKLPPHYLNALIGAFQRLERGELGIFGTQLSDYCER-VVDGKELWSLMMDPADPVVVNAINRLRASGRFKIAALTNNFLLKSMFDYIESCVEGLRKPDPRFFELALDKLGIK-AEEACFLDDIGNLISAKKLGIRTIRVVHGKSDAIKELEGVV Stehi1 KAVIFDIGGVVLSPLIAIGQYEEHGIPDNYINCSIGAWQKFERGEMPLFGTDLSDYCRR-RIDGRELFGKMMRESDECVLEAIRRIRETGKYRIIALTNNFGLRALFDFVDSSEIGMRKPETRFYAYCLERNKIA-AHEAVFLDDLGNLKAAKDMGMKTIHVPIGGSNAIKELEQVL Tapde11 KAVVFDIGGVCVSPLHAINEYESLRLPHNYLNFMISPMNLLECGQIATFERHLSDFFGS--IDGRKLWGMMMEAANTPLLDIIRDLKASGKYKVWALTNNF-IHPLFDIIGSVQMKMRKPDPRLYQYLVEELDLP-TDEIVFLDDIGNLKAAQKLGIHTIQVDFRTTVALKKLNHLL Thetr EAVVFDVGGVLTSPLPAIARYAELGVPARELAMTLTAFALLECGLIDVLDREVQLRLGT-EFAAADMFA-VLRNARPEVLQLVAEIAGAG-LAIGILTNNWELRDLVPVVESRLEAMRKPGPAIFARMLDRLGVA-PGAVVFLDDIGNVKTARLLGMHTIKVPASEEEAFDELALVL Treme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 KVLLFDIGGVCVSPFQIILDYESLGIPPGWINYSIGFWQRIERGEIPMFTRDLHV-QQA-KIDGKWLFNEMMAGADPWMYPALQKLRASGRYILAALSNTVPVRQIFDFISSAHVGIRKPDPEIYRLALEKLGIA-PKDIVFLDDIGNLKEARRQGFNTIKVHLGRTEAVEELEKIT Umbra1 KAVIFDIGGVCVSPMQGIHRYEKVGLPRNYINLSIGAFQKLERGEIKLFGEQLSHYMKK-QVDGRELFQSMMRETDERIFYAIKQLKESGKYKVAALTNNFELRSQFDFIESRIVGLRKPDPKFYEHACKVVGVE-PSEAIFLDDIGNLRSANKLGMTTIQVMMGNSPAVEKLQSLV Ustma22 KAVIFDIGGVVVSPLFAINKYEEHGLPFQYLNVAIGAFQKFERSELDLFGDELSNFCKS-RIDGRELFGQMMQQSDPRMRKAIQRLKASGQFTIAALTNNFELRSMFDYIESAVVGKRKPDPEFYQHALDLLKVQ-ASEVVFLDDIGNLKAAQKLGITTIRVNSNDCPALAQLSKLT Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3843.fasta_al_trimmed; alignment length = 68] Allma1 -------------------------------------------------------------------- Ashgo11 PKVAIVFCTGCRWRASWYAQELLQTFLAEIALVPTIWDRRRDNGFPDSKYLKQAVKATLFAALGAHIA Aspfu1 PRITIKYCTQCKWRAAYFAQELLSTFLGEVALVPVLWDRRVDGGFPEVKVLKSRVRNVVDPDLG-HTD Aurde31 PRITIEFCDRCLCRASWTQTELALTFVRAITLVPLLWDRKSEGGFPELKILKQRVRDIVQPSLG-HSD Batde5 -------------------------------------------------------------------- Botbo1 PRIVIEFCDRCRWRATWIQTELLLTFIQAITLVPLLWDRKTQGGFPELKDLKQRVRDRVQPSLG-HSD Botci1 ----------------MFAQELLSTFIGEVALQPTLWDRKSEGGFPETKE------------------ Caeel -------------------------------------------------------------------- Canalb1 PRIIIQYCHQCKWRAIWYLQEFLQTFIYDISIQPIIYRRKFKNGFPDSKFLKKLIKMELGPSIGHHLE Cangl -------------------------------------------------------------------- Capow -------------------------------------------------------------------- Catan2 -------------------------------------------------------------------- Cioin -------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------- Coere1 -----------------MAQELLTTFLGEVALVPLLFDRRTEGRFPEMKEAKQLVRNKVSPSLG-HSD Conco1 PRIEIHFCTGCKWRAGWMSQELFNTFIGELALIPLVFDRKVEGRFPEMKEVKQLVRNQIAPKLG-HSD Conpu1 PTVTIEFCDRCRWRATWVSTELLLTFIKGVSLLPLVWDRKTEGGFPELKVLKQRLRDHIDPSLG-HSD Copci -------------------------------------------------------------------- Croqu1 -------------------------------------------------------------------- CryneH991 PSVIIEFCDRCRWRATWIQTELFLTFLRSITLMPLAWDRKTEGGFPELKVLKQRIRNLVQPGLG-HSD Crypa2 PRVTIKFCTQCKWRAAYFAQELLSTFLGEVALQPILWDRKADGGFPETKELKRRVRDVIEPDLG-HVD Debha1 PRVSIEFCAACKWRAVWYLQEVMQTFIPEVALQPIIYKRKFKKGFPDSKLLKGLLRDKLFPQLG-HID Dekbr2 PIVSIAYCVRCKWRAAWYQQEILQTFINSVLLKPVLWDRKMNGGFPDSKVVKQKIRDIVKPKMR-HLD Dicdi -------------------------------------------------------------------- Dmel -------------------------------------------------------------------- Enthi -------------------------------------------------------------------- Falba -------------------------------------------------------------------- Fomme1 PSVTIEFCNRCRWRATWISTELLLTFLKGVHIIPLIWDRKVEGGFPELKVLKQRIRDRIDPSLG-HSD Fusgr1 PRVSIQFCTQCKWRAAYYAQELLSTFLGEVALQP-LWDRREDGGFPETKELKRRVRDVIEPDLG-HVD Galma1 TTVTIEFCDRCRWRASWVQTELFLTFIGSIALIPLVWDRKVEGGFPELKVLKQRIRDQLQPSLG-HSD Ganpr1 VQVDAQECVDSAG-------ALLSTFIGEIALSPVVWDRKEKKGFPEITELKRLVRDVVAPSLG-HAD Gloin1 PRVSIEYCVQCRWRAGWMAQELLITFLGEVALIPLIWDRKQAGRFPEMKELKTLIRNKIAPELG-HSD Hisca1 PRVTIQYCTQCKWRAAYFAQELLSTFLGEVSLVPVIWDRKMEGGFPETKQLKSLVRNIVDPDLG-HVD Klula1 PKVSIVFCTKCKWRSAWYVQELLQTFLKEISLIPVIWDRVVDDGFPDSKYLKQRVKALIFNAIGAHID Lacbi2 TTLVIEFCDRCRWRASWVQTELFLTFIGTISLIPLVWDRKVEGGFPELKVLKQRIRDLLQPDLG-HSD Lenti61 PSITIEFCDRCRWRATWTSTELFLTFIKAINIMPMVWDRKFEGGFPELKVLKQRIRDHIQPSLG-HSD Malgl1 PCLIIEYCDRCRWRATWLQTELLLTFIASTLLIPLIWDRKTRRGFPELRELKNLIRDRVAPNLG-HSE Mellp23 -------------------------------------------------------------------- Mnele -------------------------------------------------------------------- Monbr -------------------------------------------------------------------- Morel2 PRVEIEFCTGCKWRAGWMAQELLLTFIGELALIPVVFDRKDHGRFPEMKEVKQLVRTVIAPGLG-HSD Mucci2 PRVSIEYCPKCRWRAAWMGQELLTTFIGEFALIPVIWDRKITQRFPEMKELKQLVRDIIVPSLG-HSD Mydma -------------------------------------------------------------------- Neucr2 PRVTIRFCTQCKWRAAYYAQELLSTFLGEVALQPTIWDRKTDGGFPETKELKRRVRDVIQPNLG-HVD Orpsp11 -------------------------------------------------------------------- Pench1 PRISIQFCTQCRWRAAYFAQELLSTFLGEVALVPILWDRKRDGGFPEVKALKSLVRNVIAPDLG-HTD Phybl2 ARVSIEYCPKCRWRAAWLGQELLTTFIGELALIPVVWDRKQDGGFPEVKELKQRIRDLIAPSLG-HSD Picst3 PRVIIKYCAKCKWRALWYLQELLQTFIQDISVQPIVYQRKFKSGFPDAKFIKILIRDKLGTKLGQHVE Plicr1 PSIAIEFCDRRRRRASWVSTELFLTFLKSITIIPLVWDRKVEGGFPELKVLKQRIRDYAQPSLG-HSD Polpo -------------------------------------------------------------------- Pucgr2 -------------------------------------------------------------------- Punst1 PSIIIEFCDRCRWRAQWVSTELMLTFIKSVTVVPLVWDRKVEGGFPELKVLKQRIRDHILPSLG-HSD Rhior3 PRVSIEYCPKCRWRAAWMGQELLTTFIGELALIPVVWDRKEKKSFPELKELKQLVRDVIAPALG-HSD Rhoto1 PRLCIEFCDRCRWRATWTQTELFLTFLRSISLVPLVWDRKIEGGFPEMKELKQRIRNLIAPDLG-HSD Rozal11 -------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------- Salro -------------------------------------------------------------------- Schco3 TTIIIEFCDRCRWRATWTQTELFLTFVTSITLIPLMWDRKTEGGFPELKVLKQRIRDVIQPSLG-HSD Schpo1 -------------------------------------------------------------------- Sorma PRITIRFCTQCKWRAAYYAQELLSTFLGEVALQPTLWDRKTDGGFPETKELKRRVRDVIQPNLG-HVD Sphar -------------------------------------------------------------------- Spipu1 PRIEIEYCPGCRWRAAWMAQELLTTFVGEVALIPLVWDRKTNGGFPEIKDLKQKVRDLIAPSLG-HSD Sporo1 -------------------------------------------------------------------- Stehi1 PAITIEFCDRCRWRAQWVATELFLTFIKSITTIPLVWDRKVEGGFPELKVLKQRIRDKIQPSLG-HSD Tapde11 PRVVIEYCKQCRWRAAWYAQELLTTFIGEVALQPLVWDRKERGGFPESKQLKQLIRDVIDPSLG-HSD Thetr -------------------------------------------------------------------- Treme1 PRVTIEFCDRCRWRATWIQTELFLTFLKSITLIPLVWDRKTEGGFPELKVLKQRMRDIIQPSLG-HSD Trire2 PRITIQFCTQCKWRAAYYAQELLSTFIGEVALQPVLWDRKTDGGFPETKDLKRRVRDVIEPNLG-HVD Umbra1 PRVSIEYCTQCRWRSAWMAQELLTTFIGEVALMPLIWDRKEMQAFPDIKHLKQLVRDIIDPQLG-HSD Ustma22 PLVVVEYCQRCKFRANWISQELLSTFIASVMLVPLVWDRKVHAGFPEMKVLKQKVRDLINPDLG-HSD Walse1 PIIKIEYCDRCRWRAQWLTTELLLTFVQSVSLVPLLWDRKIKGGFPEAKELKQIVRDSIAPSLG-HSD Zygro1 PKVSIVFCIKCKWRSSWYMQELLQTFLGEVSLIPIIWDRSVEGGFPDSKCLKQRVKALLFHSIGKHNE [Cluster3858.fasta_al_trimmed; alignment length = 536] Allma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 VLEVNPVLGGEL--GVQVGQ-TVDIRVVEPEGSDDWEVIEANAMFFQD-EMLFQTRIVRCRVQRVVPARLSTDTLVVVAPRVMVAMDNLIESCHCVHGPSGMGKTSLLREVEYLLLRDTKFVDCAELP--ETNSVAKM-KQFIPTVLFLDNADFLTSTKLAHIFYVRVVLAAEKADSLNAVFHAIGHLTAPGRPEREIVAAAFADIALDTEGYSPADLETLVDKIFHEAFNQAFEGYTSASLRGIKLQK-STGVRWSDIGALDGAKRLLLETLEWPTRYAPIFSQCPLRLRSGILLYGYPGCGKTMLASAVAQQCGLNFITVKGPEILNKYIGASEQSVRELFEKAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVLCDMPAAAERAAILRAI--VTSGAILAPDVAARAAGFSGADLQGMCYNAYLKAVHRALARAQ-EIDMLAACAETKPSISSTERAKLQRIYAQFV-SERN-GD-MPPDQIGTRATLM Aspfu1 TVEVDTTFGRVL--GLSEGQ-KVGIYIIEPLTPEDWEIIELHANFLEL-NLLSQIRALNIIITSLIPAKIAPDAEVIVAPKVMVGIDQVISQSVLVTGGLGSGKTALTHFLAHRLRKDVKYFSCRKLVTDET-RISNI-KETLQSVVILDDLDKLRSRQNSEVICVVLLATAQSKESLNNVIHVVRELRAPDKEGRRVLEKLTLDLAGKTDGYMPGDLVLLVARARNEDFENAIRGFTPASLRNVTLTS-ST-TTFSAIGGLHETRKMLLETLQYPTKYAPIFAQCPLRLRSGLLLYGFPGCGKTLLASAIAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAARPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPNHSDRLDIIRAV--STK--LMDAEVAARTDGFSGADLQAVVYNAHLEAVHDALAKIE-AIHMERSLSNTRCSLSENERRRLQAIYREFV-EGRN-GE-MPGREIGGRTSLM Aurde31 TLEIDPQFATSL--GFPENA-IVEIGLTEPRTADDWEIMELHANYMEE-SLLSQVRVARFLVVSTEPCLLSTDTEVSIAPKPLAGVSAFLDRGLLLVGRPGSGRTSVAKAVAQRLQDDTLYKDMTAIA--ED-RVQVV-KAEWPSVIILDNLDVLRQRQLAEQFLVAVIAVAKGTANLHPLLHIFGLLAPPNLDARRILSELVVALATTTEGYSATDLKDLVAGAVHHDFEHAQKEFVPLSLRDVQQTKRTE-VRWADIGGLGETRRVLRETLEWPTKYSAIFAECPLRLRSGLLLYGYPGCGKTLLASAVARECGLNFIGVKGPELLNKYIGASEKSVRDLFERATAAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCNMPDMNERQEILDVV--AGK--LVSPEVAAQTEGYSGADLQALLYNAHLDAVHESIRRMA-AMHLVKALRGMKPSLPIDERLRLDFIYDQFR-VDRS-GA-LPGNGVGQRTSLM Batde5 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botbo1 TVEIDPQYASAL--GFAQGE-IVEIGLTEPLSADDWEILELHAGYVED-NLLAQVRAARFRVVSTNPVLLSTNTEVSIAPKLLAGVDAILTRGLLLCGAPGSGRTSIAKEIGKHLEEDTVYVDLAKYA--EE-REAAI-KQQFPSILVLDNLDRVRQRQLAEHFIVVMLATCQSQTALHPLLHTFATLKAPGKDARRIIARITVALATQTEGYSATDLQDLVGRAVHQDFHAAQVDFTPLSLRDVKLQK-SE-VLWSDIGGLHETRRVLRETLEWPTKYGAIFAKCPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEKSVRDLFDRATAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLLCNMPDVDEREEILRAI--GRK--VISESVAIQTEGYSGADLQALVYNAHLEVIHSAIKRME-TIHLQRSLQDTRPSVPPEERRRLGRIYKEFV-AERS-GE-LPGGSVGARATLM Botci1 VVEIDATFARTL--GISDGQ-KITATIIEPLTPEDWEIIELHANFLEL-NFINQIRALNIIVTSLLPTKLAPDAEVIVAPKTLVGIDNLMEQSVLLTGALGSGKTAVVQHLAHRLRQDTTYLSCRKFVTDEA-RVSTI-RETFKSIVILDDLDKLRSDLISEKIIVVLLATAQAKESLHKNIHCVRELKAPNKEGRRVMEKVALDLAGQTDGYMPGDLVLLVARARSEDFDSALKGFTPASLRNVTLQT-ST-TTFDSIGGLQETRKILLETLQYPTTYAPIFAQCPLRLRSGLLLYGFPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAEAARPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLICDLPNVDDRFDILKAL--GKK--LLSEEVARRTEGYSGADLQALISNAQLEAIHDVLAKLE-EIHLVKSLEGTRPSISADERRRLQGIYREFV-VGRS-GD-MPGTEVGGRSSLM Caeel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 NLEIDPVFAQSL--NLIDKT-PIIVNLLEPLTSSDWELVELHAQSIED-KLLSQTRCVKLLVTDLGSAKISPYCEIAIAPKVAIGLDNTVEDGTLVYGNSGSGKTLLLKLVAQQLNQQTKYISCDTIM--NE-NFQNLSKNHFPSVLILDNIDKLKSNQLTEFFILSILLSANSKDNINKLLHLIENLNPPDKSLRFILDKYLMDLVSETEGYLPNDLKILSDRIYHEHIEKALAGYTPSNLRGVKLQK-SS-INWSDIGGLKEAKNILLETLEWPTKYAPIFANCPLRLRSGILLYGYPGCGKTLLASAIAGQCGLNFISIKGPEILNKYIGASEQSVRELFERAQAAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVICDMPNYEDRLDILQSI--TTK--MLSDDVAEKTTGFSGADMQGLGYNAYLKAVHVTLHQIQ-QFNFLESLKETKPSISHSEKIKLTKIYKEFV-NDRD-GN-MPSNEIGGRTTLM Cangl TVEINASLAKLY--SLKPGQ-IITTSILEPNSSYDWDIIEGNSRLIQD-SILFQTRAVTFKVTRIVPVKLTDGTLVVVAPKL---IQSVLEVAFLVEGESGMGKTMLFKYLQRRLATQVMYIDCNDLL--KYSSFEKL-RRFWPAVILMDNADSVVARQTLVYLVVRVVLGAAKKYSLDAMFHFVCELKAPNRDQRAYLQGFCADIAAETEGFSVRDLKMFSEMLYYRVLDSCVKDFTPSSLRGVQLTK-GTGVRWDSIGALQEAKQILLETLEWPTRYAPVFAKCPLRLRSGLLLYGYPGCGKTLLAGAVAHQCGLNFISVKGPEILDKYIGASEQNVRELFERAQSVRPCVLFFDEFDAIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLEGVYVLAATSRPDLIDAALLRPGRLDRSVLCDMPDESARLDILRAI--TRE--QVAADVARGTRGFSGADLQSLCYNAYLKAVQRQLDQIR-KIDLQEALQETKPSVSATELARLRTVYANFA-SDRT-GE-MPPADIGTKLSLM Capow -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 AVEVDATFARLT--GLQQGQ-KVGIILIEPLTPVDWEMIELHAQFLEL-NFLSQIRALNITVTSIAPVKISPDAEVIVAPKTLVGIDPLIAQSVLLTGGLGAGKSECAQLLAHQLRTETTYFPCRKLVTDET-RVATI-KETLNAVVILDDLDKLRSRQVSECLIVVLLATAQGKEALNNVIHIVRELKAPNKDGRRVIEMLALDLAGQTDGYMPGDLVLLTSRARNEDYTKALAGFTPASLRNVTLQS-ST-TKWDSIGGLHNTRQVLLETLQYPTTYAPIFAKCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAEAARPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPDEEERIDILRAV--TAK--LLAPSIASRTEGYSGADLQAVVYNAQLEAIHDALQKIS-SLHIESSLVSGRSSISAQERMRLKRIYTEFV-DGRD-GN-LPGTEIGGRSSLM Coere1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 TIELDPQYAVAL--GFAQDD-VVEVGLTVPVGVDDWEIIEIHAAHLET-ALLSQVRVARLRVESIDPALLSTDTEVSVAPLSLIGVDEQLRDGMLITGRAGTGKTSFANAVARAVQEDVHKIDLEAYA--SK-PVKAL-KELFPAVLVFENVDKVRTRNITELFVIVMLATAQSHAGVHPLLHLWRGLMPPGRDARKSLGHLISLVASATEGFAPADLDDLVGRAVHQDFVSAQKDFVPLSLRDVPLQK-SD-VEWADVGGLGKTKRVLRETIEWPTKYAVVFRQSPLRLRSGIMLYGYPGCGKTMLASAVAKECGLNFISVKGPELLNKYIGASEQSVRDIFERATSAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLEGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPDESDRKEILEAV--SRK--VTDASVAAQTEGYSGADLQALVYNAHLAVVHAAIDRLE-RIHLLEALKTTRPSVAFEEQARLRRIYQEFT-SERG-GK-LPEQGVGSRSSLM Copci TIEIDPQFAQGL--GFMQGD-VVEIGLTEPVTSDDWEIIEIHASHVES-TLLSQVRVARLTVTGLEPLLLTTNTEVSIAPKLLAGVDDILEHGLLVTGLPGSGKSSIVRSVARSLQQNTYYVDVSRYA--ES-PIANV-KALFPGVLVLDNLDKLRSRLLTEVFLIVVIATASSVAGLHPRLHIFKEVKPPNRDARRIISRIVTALATQTEGYSASDLQDLVARAIHQDFTKAQAEFVPLTLRDVKLEK-SS-TSWSDIGGLFETKRVLRETLEWPTKYGPIFSQSPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVLCDMPDLDDRKDILRAV--AKK--LFSASIAEMTEGYSGADLQALLYNAHLDAIHASLRRLK-QIDILKAMKTMRPSVSVEERRRLGRIYRAFV-SDRS-GE-MPGGGIGSRATLG Croqu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 LVEIDPTLASTL--GLEEGQ-KVMATIIEPLTPEDWEIIELHATFLEL-NLLSQMRALNIKILSLDPAKIAPDAEVIVAPKVLVGIDSLLQESVLLTGALGSGKTSVAQSVARFLRKDTTYFSCRTLVNDES-RVSTI-RETLKALVILDDLDRLRSRHISEAICVALLATAQGKESLHNVLHLVRELRAPDKPARRIMEAITLDIAGETDGYMPGDLSLLVSRARNEDFENALKGFTPASLRNVTLQS-ST-TTFDSIGGLTETRQVLLETLQYPTKYAPIFAQCPLRLRSGILLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTLMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSILCDFPNLEERVDIIRAI--GRK--ALSEAVAKRTDGFSGADLQALVSNAQLEAIQDVLAKLE-SIHLVKALGGTRTSISREQRALLQRIYREFV-VGRS-GE-MRSMEIGGRSSLM Debha1 TLEIDPIFAQSL--SLSDKH-QVTLNLLEPVTSSDWELVELHAQILED-KLLSQSRCVKLIVTDIGTAKISPMCEVAIAPKVVIGLDNMIEEGTLIYGNSGSGKTLMLNLIASKINSDTKYISCEKIM--NE-NFNLLSNNHAPSLLILDNLDKIVSNQLTEFLILSILISATSKEALNKLLHLLEHLSPPDKNTRLIINGYIMDMVSETEGYLPNDLKILCDRIYHEHFEKALKGYTPSNLRGVKLQK-SS-ISWSDIGGLKDAKNILLETLEWPTKYAPIFANCPLRLRSGILLYGYPGCGKTLLASAIAGQCGLNFISIKGPEILNKYIGASEQSVRELFERAQSAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVICDMPSFEDRLDILESI--TTK--MLMEDVAEKTAGFSGADMQGLGYNAYLKAVHVKLQQIE-QLDLLDSLKETKPSISVSEKTKLQKIYNQFV-SGRD-GN-MPNNEVGGRTTLM Dekbr2 TVEIDPSFATIS--HIKEGL-EVSIQILEPTTTEDWELTEMYAGTIED-KFLNQIRALKFLVKEVCSGLLTNNTELHIAPKIMIARDKELSDNCIIYGASGSGKTMLCKKLSSQFHSKTKEIDCNEII--STLNLEKLKKLLTPSILLLENADSLFSTQLAELFSVSLVVTCKTRDSINPLIHLVEESKSPTKEQRLLLINFIRDVAADTEGYLPYDLKCLCDRAFHDNFVHSLKGFTPSSLRGVKLQK-STGTSWNSIGGLKQAKQILLETLEWPTKYAPIFANCPLRLRSGILLYGYPGCGKTLLASAVASQCGLNFISIKGPEILNKYIGASEQAVRELFERATAAKPCILFFDEFDSVAPKRGHDSTGVTDRIVNQLLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSVLCEMPNYENRLDILKTILKSNK--FVAEDVARKAAKFSGADLQALIYNSYLKAVHEDLASNR-GLHFKQGLSETNRSISNKQIKKLDQIYEKFTENRRA-GD-LRSQNIGERTTLM Dicdi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 TIEIDPQFASGL--GLSLGD-IVEIGLTEPYSADDWEIIELHAAYVEQ-NLLSQVRAARLRVVSFDPVLLGTDTEVSIAPKRLAGIDDFLEKGILITGRPGSGKTSVAKAVAKMVESSVIYVDFAKLA--DE-RVPRL-KAYFPTTLVIDNMDKLRSRQLTELFLVSIVATAESDTALHPRVHIFKSLMPPNKDARRILSQSVTALATQTEGYLPTDLNDLVSRAVHEDFEKAQVDFVPLSLRDLKLQK-SD-VTWSDIGGLRKTKQILRETLEWPTKYAAIFAKCPLRLRSGILLYGYPGCGKTLLASAVARECGLNFISVKGPELLNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLLCDMPDFDERKEILEVI--SKK--VVSPFVALATEGFSGADLQAVIYNAHLDVVHSTLKKLQ-RIHIRRSLTSTRPSVPLEERVRLQLIYSAFV-SDRS-GE-MPSGSVGTRASLM Fusgr1 LVELDATLAKTL--GLSEGQ-KIMATIIEPLTPEDWEIIELHATFLEL-NLLSQIRALNIKVISLDPAKISPDAEVIVAPKTLVGIDSLLNNSVLLTGGMGSGKSSIAKHLAQKLRQETLYYPCRKLVNDET-RISTI-KETLKAVVVLDDLDKLRSRQVGETLCVVLLATAEAKESINGVVHVVRELKAPDKEARRVMESIVLDISGSTDGYMPGDISVLVSRARNEDFEKALKGFTPASLRNVTLQS-SS-TSFKSIGGLQETRQVLLETLQYPTKYAPIFAQCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFDRASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPALEDRVDIIKAL--FQK--VLSDELARQTEGFSGADLQALVSNAQLEAIHDVLAKLE-EIHLLKALDNTRASISSEEKRRLQRIYTEFV-VGRS-GQ-MKSMEIGGRSSLM Galma1 TIEIDPQYSQSL--GLSLGD-IVEIGLTEPLTSDDWEIIEIHASHVES-TLLSQVRVARLRVTSLDPLLLTTNTEVSIAPKLLAGVDQILERGLLLTGRSGAGKTSIVQSVAKSLQEDTHYVDASKFS--EH-PISSV-KAQLPSVLILDNLDKLRSRHLTEMFLIVLLATADSTASLHSFIHVLKEVAPPNKDARRILSRLVTELSTQTEGYSATDLKDLVARAIHQDFTAAQVGFVPLSLRDVKLEK-SD-VAWSDIGGLYETRRMLRETLEWPTKYGPIFKQSPLRLRSGLLLYGFPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLFCDIPNFEERKDILKAV--AQR--MVSQIVAAKTDGFSGADLQALLYNAHLDIIHTSIRRLR-QIDILKALKSTRPSVSEEERRRLGRIYQEFI-SDRS-GN-LPAGGIGNRATLG Ganpr1 VVEVDATYGRAL--GLTEGQ-KVSVAVVEPVSEDDWEILELHAGVVEG-QLLSQLRVVRLKVLSFDPVRLDNDTEVVVSPKTLGGVSAVLKNGLLLVGGHGAGKTSVCKTIMQQQSRSCALVSCADLA--EE-RVAKV-RERIPSIVVFDDLDRLRYRQLSEMFLVVIVATCQQQASLHAGIHIFDELYPPNKVQRKILEAVLASISSSTEGYLPADLRTLTERAVHEDFERAQKDFVPSSLRGIKLQK-TE-VSWKDVGGLIETKRVLKETLEWPTKYAVIFANSPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEAAVRDLFERAQAAKPCVLFFDEFDAIAPRRGHDNTGVTDRVVNQLLTQMDGAEKVEGVYVLAATSRPDLIDPALLRPGRLDKSLLCGMPDEEERKDILESV--ARK--VLHPSVANRAEGFSGADLQALLYNAHLEAIHDLMSRLE-TIHLESAFXTTRPSLAAHEVRRLDRIYEEFL-GGRS-TT-VP----GTRATLA Gloin1 IIEIDPQFGTAI--GLHDGQ-KVSMKIVEPFNIEDWEIMDRRANYLED-YIVQQLRVVRLRIVEINPAKLCANSEVFVKPKPLAGVSNLIQQGLLLCGGHGSGKTSIAKTITYNLGRDCLVVRCTELT--EE-RISSV-RDKLPSIIFFDDLDRLRFRQLSECFFITIFATAQQQSSIHSFLHLFSELDPPTKAERRILEAIMLSVASECEGYFAADLKVLVERTIHEDFHKAQEGFVPFSLRGVKLHT-SE-VSWTDIGGLEETKKVLLETLEWPTKYASIFANCPLRLRSGLLLYGFPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSLLCNIPTFQERIEILKAL--SRK--MLNEDIAEKCEGYSGADLQALLYNAHLKAIHEAIQRLA-LIHMRASLEITRPSTTPEERARLSNIYEEFI-TGRN-GE-MPSHEIGQRSTLC Hisca1 TVEIDSTFGRVL--GLSDGQ-RAGLLLIEPLTPADWEIIELHATFLEL-NLLSQIRALNITITSLTPAKIAQDAEVVVAPKILVGIDTVIENSILLTGGLGAGKTSLCQLLAHNLREDVSFFSCRKLVTDET-RISTI-KETFQSLVILDDLDRLRSRQISEIVCVVLLATAQAKESLNNVIHVVRELKAPNKDGRRVLEKLTLDLAGKTDGYMPGDLVLLTARARNEDFSHALKGFTPASLRNVTLTS-SS-TAFASIGGLHETRKTLLETLQYPTTYAPIFAQCPLRLRSGLLLYGFPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAEAARPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPSHSDRVDIVQAL--SKQ--LLSEEVADRTKGYSGADLQAVVYNAHLEAIHDALAKLD-AIHMERSLATTRCSISDVERNRLEAIYKEFI-VGRN-GE-MPGREIGGRTSLM Klula1 ILEMNAILAGEY--RLQMGQ-LVDISVVEPNTFQDWERIDANSAYFQD-QILYQTRLVKFTINSISPGRLTNDTLVIVSPKVIVGITEMYHESFLIQGGAGMGKSIILENLRHDLI-NVNYINCDSIP--DSTNLAKT-KQYIPSIILLDNADSLPSTKLTQIMMIKIVMTAKSSESLNKIFQFIGDLKPPTRYQRNILNQLLADISIETEGYSPADLRLVVDRFFYELMESCLTGFTPASLRSVKLQK-STGVKWSDIGGLTNAKRLLLETLEWPTKYAPIFASSPLRLRSGILLYGYPGCGKTMLASAVAQQCGLNFISVKGPEILNKYIGASEQSVRDLFDRAQAAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVICDIPDVTEREDILRAV--TLK--MTEDDLAIRTEGFTGADLQGMSYNAYLKAVHRSLDRIT-ELDMLDACQEAKPSISTHELQKLSHIYQKFI-GDRE-GK-MPSQEVGGRTTLA Lacbi2 TIEIDPQYSLGL--GLAQGD-LVEIGLTEPLSSDDWEIIEIHASHVES-TLLSQVRVARLRVTSLNPLLLTTNTEVSIAPKLLAGVDEILGRGLLVTGRAGSGKTTLVREVAKTLQQNVHYVDASLYA--DK-TVSAL-KALFPSVLILDNLDKLRTRHLTSIFLIVLLATASSTAALHSYIHLFKEVHPPNKDARRILARIVAALATQTEGYSAVDLQDLVARAVHQDFMAAQADFVPLSIRDIKLEK-SD-VAWSDIGGLYETRRILQETLEWPTKYGPIFAQSPLRLRSGLLLYGFPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLEGVYVLAATSRPDLIDSALLRPGRLDKSLFCNMPEYEERKDILKAV--ANK--LVSPSVAAETDGYTGADLQALLYNAHLQVIHASIKRLR-QIHICLALKTTRPSLALEERQRLQRIYQGFT-SDRS-GD-LPAGGIGSHVTLM Lenti61 TVEMDPQYAEGL--GFALGD-VVEIGLTEPVTSDDWEILELHASHVES-TLLSQVRVARLNVVSLQ-LLLTNSTEVSIAPKVLAGVDELFAKGLLVTGRSGAGKTALLHAISKAMQNDTLYVDLSRYA--AS-PIAKI-RSSMPSLLVLDNIDKLHTRHVTELFLVILLAAAESQASLHPLLHVFQELKPPSKDARKVLGHLVTALATQTEGYSVTDLKDLVARAVHRDFASAQVDFVPHSLRDVKLQK-SD-IAWTDIGGLRETKRVLRETLEWPTKYGPIFAQSPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISIKGPELLNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLEGVYVLAATSRPDLIDSALLRPGRLDKSLLCDMPSAEERQEILEAL--GRK--VFGPDVAEATDGFSGADLQALVYNAHLEVVHDAIRRLQ-RIHLERVLQITRPSVPGEERERLRRIYGAFV-SDRS-GD-LPAGGVGKRVSLA Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MIEMDPQFGQAM--GLRAGQ-KVNIEFVAPYSEDDWEILELHAGYVED-QMLNQIRILRLRVLDINPVKLGANAEVIVAPMVLGGVTQVLTKGFLLCGPHGSGKTVVARSLIRKLAQNCVEINCAEFA--ED-RLPVL-MTKFPSILFLEDLDRLRSRQIAEVFLIAIVATAQQQVSVHPSLHLLSELMPPGKTERKMLKSLMVSVASKTEGYLAADLKAFLERTVHEDFLKAQEGFVPSSLRGVKLQS-SA-TSWLDIGGLNETRKILLETLEWPTKYAAIFSQCPLRLRSGLLLFGHPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSLLCGMPSLEERHEILACL--ARK--MVADDVARRTEGLTGADLQAVLYNAHLEAIRVAIQRLG-LIHLEVSLNNTRSSITPEESQRLDLIYSEFM-GDRN-GE-MSSHELGQRTTLA Mucci2 VLEMDPQWGMAV--GLQDGQ-KVNVEFVEPLTEDDWEILELHAGYVEE-NLLSQIRVVRLAVAELDPLKLTNQSEVIVAPKVLGGVDKVLQKGVLVTGTHGSGKTSVVKTILNRVRSSTMEINCSEIA--DE-RIPVF-KEMLPSLIFFDDLDRLRSRHLAELFVIMMMATAQQQQSLHPALHIFSELQPPNRDERKIMQAIMVSVASETEGFLAADIKAFIERTVHEDFTKAREGFVPTSLRGVKLQS-SG-VNWSDIGGLNETRKALLETLEWPTKYAAVFAQCPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPRRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCGMPTFDERLEILEAL--ASK--MLAADVAKKTEGFSGADLQGFLYNAHLEAIHGAIQRVSGKLYLEKSLKSTRPSITAEEAHRLGLIYNEFV-TGRT-GE-LPDKGVGKRSTLG Mydma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 LVEIDTTLAGTL--GLKEGQ-KVMATVIEPLTPDDWEMIELHGTFLED-NLLFQVRAINIKVISIDPAKIAPDAEIIVAPKVLVGIDSLLEKSVLLTGGQGSGKTSVAQSIARTLRSTTTYFPCTKLVNDES-RISNI-KETLKAVVVLDDLDKLRSRQISEAICVVLLATCQGKDSLHNVIHVARELSAPDKETRRIMEALTLDIAGQTDGYMPGDLILLISRARNEDFDAAISGFTPASLRNVTLQS-SS-TTFASIGGLQETRQILLETLEYPTKYAPIFAQCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDFPNLEDRLDIIKAL--THK--VVAEEVGKRTDGFTGADLQALVSNAQLEAIHDALAKLE-TLHLYKALDATRASISVKERKRLERIYHEFV-VGRS-GE-MRSNEIGGRSSLM Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 TVELDTTFGRLL--GLTEGQ-KVGLFIIEPLTPEDWEIIELHATFLEL-NLLSQIRALNIVVTSLTPAKIAPDAEVIVAPKVLVGIDSMIEQSILVTGGLGAGKTALTHLLAHRLRRDVKYFSCRKLVTDET-RISNI-KETLQSVVILEDLDKLRSRQNSEVICVVLLATAQAKESLNNVIHVVREMRAPDKEGRRVLEKLTLELAGKTDGYMPGDLVLLVARARNEDFESALKDFTPASLRNVTLTS-ST-TTFSSVGGLFETRKMLLETLQYPTKYAPIFAQCPLRLRSGLLLYGFPGCGKTMLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAARPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPNHADRVDIIRSV--AEK--LMSDEVATQTEGFSGADLQAVVYNAHLEAVHDALAKLE-AIHVERSLATTRGSLPPAERRRLQGIYREFI-AGRN-GE-MPANEIGGRTSLM Phybl2 VLAIDPQFGQAI--GISEGQ-LVNVEFVEPHTEDDWEILELHAGYVED-NLLSQIRAVRLRVAEISPVKLTTNAEVIVAPKVMGGVDTIYGQGVLVTGAHGAGKTSLVKKLMEDVYHDTITVQCSELV--DE-RVPVF-KDMLPSVLFFDDLDRLRSRHLAELFSIMIIATSQQQQSLHPTMHVFTEVNPPTRDERKIMHAIMVAVASDTEGYLAADLTALVERAVHEDFVSARQGFVPSSLRGVKLQS-ST-VQWTDIGGLHETRKALLETLEWPTKYAAVFSQCPLRLRSGLMLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFDRAQAAKPCVLFFDEFDSIAPRRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCGMPSFEERLDILEAL--SHK--MLASDVAQNTEGFTGADLQGFFYNAHLEAIHDSMQRLA-MIHLDKSLKSTRPSITADERLRLQLIYDEFV-TGRT-GE-LKAKGVGKRSTLG Picst3 TVEIDPVFAGAL--GLKDDE-KITLNLLEPVTSSDWELVELHAQAIED-TLLLQTRCVKLVVVDIGSAKISPYCEIAIAPKVVIGLDGVIDEGTLVYGNSGSGKSLVLKLASRKIAAETKYVSCDSLM--NE-SFNLLSKNHIPSLLILDNVDKIKSNQLTEYLILSILLSASSKEAINKLLHLIENLSPPDKALRLILDNYIMDLVTETEGYLPNDLKILSDRIYHEHIEKSIQGYTPSNLRGVKLQK-ST-ISWSDIGGLKEAKNILLETLEWPTKYAPIFANCPLRLRSGILLYGYPGCGKTLLASAIAGQCGLNFISIKGPEILNKYIGASEQSVRELFERAQAAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVICDMPDYDDRLDILKSI--TDK--MLADDVAEKTSGFSGADMQGLGYNAYLKGVHVKLNQIQ-QLNFRESLVETKPSISYSEKRKLERIYSQFV-SARD-GN-MPSNEIGGRTTLM Plicr1 TVEMDPQYAQAL--GLVMGD-VVEIGLAEPVSTDDWEIIETHAGHLEQ-ALLSQVRVARLRIVSLD-LLLGNNTEVSVAPKVLAGVDDILARALLVTGRAGAGKTSIVQSVARTLREDTLYVDLGKYV--EH-PVSQV-KSLFPTVLVFDNMEKLRTRHIVELFVIVVLGAAQSQAALHPLLHLFDDVKPPNKEARKIIVQIITALATQTEGYSATDLQDLVARAVHHDFETAQVDFTPLSLRDVKLQK-SD-VEWSDIGGLQETRRVLRETLEWPTKYGPIFAQSPLRLRSGLLLYGFPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLLCNMPDASERKDILQAV--SRK--VLAPTVARATEGFSGADLQALVYNAHLEVVHASIRRLQ-QIYLRRVLQTTRPSVSPEEQYRLRQIYKAFV-SDRS-GD-LPAGGVGNRASLM Polpo -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 SLELDEALASEM--GWKQND-RLSIKFVEPLTIDDWEILESNPQYLEE-NILKQIRVLQVKVTSVLPYLITNETEIIVSPKTLLGFSEHLDFGLMIRGSSGSGKTSLVKTLIERVYLDCRYIDCGKHV--DD-RLNVL-KSNFPSVLVLDDLDQLRYRHLAEEFLVILVSTCSSSVSIHNLLHIFSELKGLSRTSRRILTELI---SEKTEGYLPSDLKDLVDRAVHQDFESAQSGFVPISLRDVKLQK-ST-VNWSDIGGLVETRRILRETLEWPTKYPSIFANCPLRLRSGLLLYGYPGCGKTLLASAIAKECGLNFINIKGPELLNKYIGASEQSVRELFDRAQVAKPCVLFFDEFESIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLEGVYVLAATSRPDLIDPALLRPGRLDKSLLCSMPKVEERLDILKAV--SRA--LLDGDLAELTEGFTGADLQALIYSAHLEVVHESIKRLE-EVHVRSALRNARPSVPAKELARLSKIYQSFV-SSRSDGG-LPSEEIGGRASLM Punst1 TVEIDPQFAQGL--GLTAGK-IVNLSLTEPVSADDWEIIELHGSHIES-TLLQQARVARLRVVSLAPLLLTADTEVSVAPKILAGVKDILIKGLLITGKSGSGKTSIAQAIARSLQDQHHYVDASRHA--EK-PVGAL-QKLFPSVLVLDNIDKLRDRHVAELFLIVLIATAESSVALHPVLHLFGELKPPNKEARRILANVVTALATQTEGYSAIDLHDLVARAVHQDFASAQVDFVPLSLRDVKLQK-SE-VAWSDIGGLHAPKRILRETLEWPTRYGPIFAQSPLRLRSGILLYGFPGCGKTLLASAVARECGLNFISVKGPEILNKYIGASEQSVRDLFERASAAKPCVLFFDEFESIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSVLCDMPNLDERREILESI--SKK--MMSSDVARLTDGYSGADLQALIYNAHLDVIHSSIRRLA-QMHLRRVLQTTRPSVAPEERQRLQFIYHDFV-DDRS-GD-LPPLGIGIRATLA Rhior3 -----------M--GLQEGQ-KVNVEFVEPLTEDDWEILELHAGYVED-NLLSQVRAVKLVVGGIEPAKLTNKTEVIVAPKTLGGVDKLLNKGVLLSGTHGSGKTSIMKHIMKSARRSTMQVNCSEMS--DE-RVPVL-RDLFPSVLFLDNLDRLRSRHLAELFVIMIAATSQQQQSVHPALHILSELQPPNRDERKILEAIMVMVASETEGFLAADIKAFVERTVHEDFTKAREGFVPSSLRGVKLQS-SG-VNWSDIGGLNETRKALLETLEWPTKYAAVFSQCPLRLRSG----------------------------VKGPEILNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPRRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCGMPTTKERLEILQAL--STK--MLADDVAKRTKGFSGADLQGFLYNAHLEAIHNSIQRLT-MIYLEKSLDSTRPSITIEEYIRLKSIYDEFV-TGRT-GE-LPAKGIGKRSTLG Rhoto1 RVEMDPQFAAMLNVGLSEGL-TVNIELVTPSTADDWEILETNAEFVEM-YLLNQVRAVRFVVDSTSPVLLTSSTELIVAPKSLAGIDKPLTQGVLVTGASGAGKTALVKMVAEEMEKDTIYVDCSKHA--DE-RLPTL-KGRMPAVLVLDNLDRMPAVHLANTFLIVLIATAQGSTSLHPLLHLLGELRGPDKTARRILNVLVASIAAVTEGYLPADLRDLVDRAVQQDFSAAQQGFVPLSLRDVKLQK-SE-VQWADIGGLTEARKTLRETLEWPTKYGAIFASCPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFERAQAAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSVLCDMPNEQDRLEIMESA--ARK--ILSSSVAAQTAGFSGADLQALIYNAHLDAIHATIKRLE-QIHLQKSLQTTRPSVPAEELARLRRIYSEFV-SGRSAGG-LPSDEVGGRASLM Rozal11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 VVLINPVLATVY--DLNQKSPLVDLYIVTPETSDDWEIIDANAMRFQNGEILHQTRIVKFKIDRVEPARITDGSLVVVAPKVFITVNSIKKEAIILDGKQGIGKTRLLKELINEVEKDVKYADCETLH--ETSNLDKT-QKLIPSLIVLDNVEALNASKLLNFFIIRVLFSGKQKTQINPLLHFVSELRAPDKHARALLEYFFSDLSLETEGFSPLDLEIFTEKIFYDLFSKSLSAFTPSALRGVKLTK-ETNIKWGDIGALANAKDVLLETLEWPTKYEPIFVNCPLRLRSGILLYGYPGCGKTLLASAVAQQCGLNFISVKGPEILNKFIGASEQNIRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLDGVYILAATSRPDLIDSALLRPGRLDKSVICNIPTESERLDILQAI--VNS--KLEKNAAEKTAGFSGADLQGLCYNAYLKSVHRWLV------DLLEACQETKPSISTSELVKLRGIYDRFQ-KDRN-GE-MPSIDIGSRLSLM Salro -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 TIEIDPQFAQDL--GLAQGS-LVEIGLTEPVSSDDWEIIELHAGHVES-TLLSQVRVARLLVGSLDVALLTTDTEISIAPK-LAGVDEIINKGLLLTGRPGAGKTSIVRAVARLLEYDTLYADASAIS--EK-PISAI-KAQFPAILILDDVDKLRARHIVELFLVLLIATASSSAALHPLLQVFAEVMPPGKEGRKILSRIVTALAMQTEGYLATDLQDLVARAVHQDFEEAHKGFTPLSLRDVKLEK-SE-TAWADIGGLGDTKRILRETLEWPTKYGPIFAQSPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRELFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLEGVYVLAATSRPDLIDSALLRPGRLDKSVFCNMPTAEERKDILSAV--ARK--VLAPEVAEATEGFSGADLQALLYNAHLEAVHESIRRLQ-QIHIRRVLRSARPSVAPEEQARLARIYSAFV-DDRS-GE-LPANGVGIRASLA Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma LVEIDTTLAGTL--GLKEGQ-KVMATVIEPLTPDDWEMIELHGTFLED-NLLFQVRAINIKVISIDPAKIAPDAEIIVAPKVLVGIDSLLEKSVLLTGGQGSGKTSVAQSVARTLRSTTTYFPCTKLVNDES-RISNI-KETLKAVVVLDDLDKLRSRQVSEAICVVLLATCQGKDSLHNVIHVARELSAPDKETRRIMEALTLDIAGQTDGYMPGDLILLISRARNEDFDAAISGFTPTSLRNVTLQS-SS-TTFASIGGLQETRQILLETLEYPTKYAPIFAQCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDFPNLEDRLDIIKAL--TQK--VVAEEVGKRTDGFTGADLQALVSNAQLEAIHDALAKLE-TLHLYKALEGTRASISVKERKRLEKIYHEFV-VGRS-GE-MRSNEIGGRSSLM Sphar -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 YLELDAQYGRAL--GLREGQ-VVNVEFVEPLTADDWEILELHAGYLEE-QFLNQVRIVKLKVVETNPIKLDTDAEVIVAPKQLGGIEPLLDTGILLYGARGSGKTDITRLVAHRLSLDTLVITCTSLV--SE-RIAKI-KDLWPSIIVFDDLDRLRARQLSEIFLLVLVATCQQQTSIHPSLHLFGEVASPTKLQRQILHTLMLSVAGSTEGYSPADLKVLVERTVHEDFVVAQKGYVPASLRGVKLQS-SE-VSWADIGGLNATKRTLLETLEWPTKYAAIFASCTLRLRSGLLLYGFPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEQSVRDLFERASAAKPCVLFFDEFDSIAPRRGHDNTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDIIDPALLRPGRLDKSLFCGMPEFEERLEILRAV--ANK--LLSPSVAERTAGYSGADLQALLYNAHLEAIHEVITRIE-SIHIDSALKSTRPSISEQEKRRLQRIYDEFI-GGKV-GQ----EGVGQRATLA Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 TVEIDPQYSQSL--GLSQGD-IVDIGLTEPLTPDDWEILELHADHVEA-NLLSQVRVARLRVVSLDPLLLTTSTELSIAPK-LAGVDTVLFKGLLITGRTGAGKTSVAQATAKALQWNTYYIDLGRWV--DK-PVPTL-RTQFPSVLLFDNMDKLRTRHIVETFLIIVLATAQSEAALHPLIHLFKRLKPPSKDTRRILHQAVVALATETEGYMPTDLKDLVGRAVHQDFRSAQVDFVPLSLRDVPLQK-ST-VEWADIGGLRETRQTLRETLEWPTRYAAIFAQSPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFITVKGPELLNKYIGASEKSVRDIFERANAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTLMDGAEGLEGVYVLAATSRPDMIDPALLRPGRLDKSLLCHMPTEPERAEILRAL--SRK--VMSASVAQRTEGFSGADLQALVYNAHLEVVHSSMRRLR-QMHLHGVLKTTKPSVSPEDIARFSRIYAAFN-SDRA-GD-LPEEGVGQRVSLM Tapde11 TIEIDPAFAKNI--GVSEGT-ELKVDLVEPVTADDWEIMELHASFLEL-NLLNQIRAVSVIVRKIEPAKISTNAEVVVSPKTLKGVETVAMKGVLLHGSRGSGKSSIASMCAKCLEERVVIADCSKL--SEE-RVSTV-KEALPSVIMIDDLDRLRARQLAEIFLISILATCQAKEALHSLLHVFDELKPPAKTARGIAQSLVLEIANMTDGYLAGDLKFLTERAKHEDYEKAISGFTPASLRGIKLQK-SS-VEWKDIGGLVETRRILLETLEWPTRYAPIFANCPLRLRSGLLLYGYPGCGKTLLASAVASECGLNFIAVKGPEILNKYIGASEKSVRDLFDRAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLEGVYVLAATSRPDLIDPALLRPGRLDKSLLCNMPAREDRCAILAAL--SRK--MVASEVAARTEGFSGADLQAVLYNAHLEAIHDVLARIE-AINLEKSLGSTKPSISAAERQRLDRVYHDFV-DGRS-PDGLPGEQ---RATLA Thetr -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 LVEIDATFANTL--GLTDGE-RVMATVIEPLTPEDWEIIELHATFLEL-NLQSQIRALVIKITSLEPVKLSPNAEVIVAPKTLVGIDTLLANSVLLTGTKGSGKTSVARYLASRLREETIYFSCRKLVTDEA-RISTI-KETLKALVVLDDLDKLRSRQVSETIRVTLLATAEGKDTLNSVVHVVRELKAPDKDGRRIMEAIVLDIAGQTDGYLPGDLTVLIARARNEDFDKAIKGFTPASLRNVSLQS-ST-TTFKSIGGLQETRQVLLETLQYPTKYAPIFSQCPLRLRSGLLLYGFPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFDRASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDLPSLEDRVDIIKAM--LQK--VLSSELALKTEGYSGADLQALVSNAQLEAIHDVLSKLE-QIHLTKALESTRASIGKDEKARLQKIYHEFV-VGRS-GQ-MKSMEIGGRSSLM Umbra1 ILELDPQFAQAI--GITNGQ-KVSVDFVEPYTEDDWEILELHAGYVEE-NLLSQLRVVRLQIGDMSPTKLTNNSEVIVAPKVLGGVEETFNKGVLLTGSHGSGKTSIVDQVIDKLKNDSIEINCADVA--DE-RVPVL-KDQLPSILFFDDIDRLRAKQLAEIFMIVIIATSQQQQSIHPSLHIFNQLNPPGRDERKILHAIMVSVATETEGYLAADLKALIERAVHEDFQTAQEGFVPSSLRGVKLQS-SG-VNWADIGGLNETRKTLLETLEWPTKYASIFANCPLRLRSGLLLFGYPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEKSVRDLFERAQAARPCVLFFDEFDSIAPRRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCGMPSIEERLEILHAL--GRK--MLSDNVAELTEGLSGADLQAFLYNAHLESIHSAISRLN-MIHLNKSLKNTRPSITIDEHRRLKAIYDEFV-TGRT-GE-LPAKGIGKRTTLG Ustma22 VLNISPSLAASFHPPLPDGA-TCSVRLVTPLSADDWEILSLHAEEVEL-NMLGQVRAARFRVDSTTPVRLSTDTEVIIAPRLLAGVDRILSDSLLLSGGPGAGKTVVAKQLAANLSSDTSYFDCSPYS--EE-RVPVL-RARFPSLLILDNIDRIRSRQLAEAFVVFVVATAQGSTSVHSLLHLWLDLKPPGKDGRRILSHLVVTLATQTEGYLPADLRDLVERATHQDFTQAQDGFTPLSLRDVKLEK-SS-VAWSDIGGLVETRRVLRETLEWPTKYAAIFASCPLRLRSGLLLYGYPGCGKTLLASAVAKECGLNFISVKGPEILNKYIGASEKSVRDLFDRAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDSALLRPGRLDKSLLCDMPGLEDRVDIMKAI--ARK--VLHPDVATRTEGFSGADLQALLYNAHLEAIHESIRKLE-LVHLETSIKSTRPSVPLEEQQRLRGIYRTFA-GDRD-GN-FPSTQIGARSSLM Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 TIDINPILAREF--GLVMGS-LVDLTIVEPESSDDWEIIESNSMFFQD-EILHQTRIVKFRINRIFPARINTGSLIVIAPRELVTTDLI-KQCAMLEGGSGMGKTTLLQQLAKELILKVKYVDCDSLM--ESSNLTRM-KQFLPSVLLLDNASTLTSTKLAMTLIVRVVICDKNKHELNGSFHFVSEIKALDTDGRTMIQFFIRDIALETEGYSPLDLELLVEKMFYNLFQETLKSFTPSSLQGVKLTK-STGVKWDDIGALKAPKRLLLETLEWPVKYAPIFANCPLQLRSGVLLYGYPGCGKTLLASAVAQQCGLNFITVKGPEILDKYIGASEQNVRELFERAQSVKPCILFFDEFDSIAPKRGHDSTGVTDRIVNQLLTQMDGVEGLDGVYVLAATSRPDLIDPALLRPGRIDKSVLCNIPSLVDRHDILRAI--TSK--MILQGTAQQTEGHTGADLQGLCYSAYLKAVHRELVRLF-TSDLLDAAKETKSSISTHELYKLRSIYDRFQ-DNRD-GQ-MPSVETGTRTSLA [Cluster3866.fasta_al_trimmed; alignment length = 56] Allma1 -------------------------------------------------------- Ashgo11 TFNCECNDTVPKKNTEKHYYRCYTCIDCSTTFGYQKHTQCITEDEKYQKALYKGKK Aspfu1 -------------------------------------------------------- Aurde31 SFNCDCNDTVKKPKLDQHAGRCFTCLDCSTTFDWRPHTTCISEAQKYEKSVYKGPK Batde5 SFSCECQETIKKPKLEQHYYRCYSCVDCSTTFDYRAHTSCISEAEKYQKSVYKPPK Botbo1 SFQCDCSDTIKKPKLDQHGARCFTCLDCSTTFQWKGHTSCISEAEKYQKSVYQAPG Botci1 -------------------------------------------------------- Caeel -------------------------------------------------------- Canalb1 SFSCECNDTVIKKKLDQHAQRCFTCIDCSTTFDYRKHTSCISEAEKYEKGLYKGKN Cangl TFNCECNDTVPKKNTEKHYYRCYTCIDCSKTFSYKQHTQCISEDEKYQKALYKGKK Capow -----MQKVVKKPKAEQHSYRCFSCIDCGNSFEFQSHVSCISEQEKHQKSLYKGPK Catan2 -------------------------------------------------------- Cioin -------------------------------------------------------- CocheC53 -------------------------------------------------------- Coere1 SFVCNCQETLKKPKLDQHAQRCFSCIDCSVDFTYRQHTSCISEVEKYE-------- Conco1 SFVCNCQETIKKPKLDQHRGRCFSCIDCYTDFEYRSHTSCISEAQKVQGSLFKGNK Conpu1 -------------------------------------------------------- Copci -----CGDVVKKPKLDQHAGRCFDCIDCSKTFEWKGHTSCISEAEKYQKSLYKGPK Croqu1 SFNCDCGDVIKKPKLDSHSSRCMTCLDCSTTFSWKGHTSCITEAEKFEKSVYKPPK CryneH991 -------------------------------------------------------- Crypa2 -------------------------------------------------------- Debha1 SFSCECNDTVLKKKLDQHTQRCFSCIDCSVTFEYRQHTSCISEAEKYEKGLYKGKK Dekbr2 SFSCECGETVPKKKCSQHQRRCFTCLDCQKTFEYINHTSCISEAEKYEKKFYKGNK Dicdi SFSCDCGDILEKKKLAFHRCNSYSCVQCSGRFSSKAHSICISEEQKVQGKLYRGPR Dmel -------------------------------------------------------- Enthi NFTCDCGETIKKSKAKAHASKCYTCIDCHKSFEFDAHKQCITETEAYQGAYLKKKQ Falba -------------------------------------------------------- Fomme1 SFQCDCQDVVKKPKLDAHSYRCFTCVDCSKTFEWKGHTSCISEAEKYQKGLYKGKK Fusgr1 -------------------------------------------------------- Galma1 SFQCHCGDVVKKPKLDQHRTRCYDCIDCSKTFEYKGHTSCISEAEKYQKSLYKGPK Ganpr1 SSHSDCQETIKKPKLDQHAQRCFSCIDCGVSFEYRAHSSCISEAEKYQGVLYKGPK Gloin1 SFSCDCADIVRKPKTQQHLSRCFTCIDCNTTFNFIRHTSCISEAEKYQKSLYKVHK Hisca1 -------------------------------------------------------- Klula1 TFNCECNDTVPKKNTEKHYYRCYTCIDCNQTFSYKKHIQCITEDEKYQKGLYKGKK Lacbi2 SFQCHCGDVVKKPKLDTHRSRCFDCIDCSTTFEYKGHTQCISEAEKYQKSLYKGPK Lenti61 ---LTCGDTVKKPKLDKHHTMCVTCLDCSTTFQWKSHTQCISEAEKYQKGLYKGPK Malgl1 SFVCDCGDVVKKPKLPQHFNRCFTCLDCSVQFE--AHNSCVTEDEKYQKSFYKNKK Mellp23 SFNCDCGDVIKKPKLDSHSYRCFTCLDCSITFTWKSHTSCITEAEKFEKSVYKGPK Mnele -------------------------------------------------------- Monbr -------------------------------------------------------- Morel2 SFVCDCQETVKKPKLDQHFNRCFSCIDCSVSFEYRSHTSCISEAEKYQKALYRGPK Mucci2 SFQCDCGDVVKKPKLNQHGNRCFTCIDCSTTFSYQSHNSCMTEAEKFQKHIYQNKN Mydma -------------------------------------------------------- Neucr2 -------------------------------------------------------- Orpsp11 -------------------------------------------------------- Pench1 -------------------------------------------------------- Phybl2 SFQCDCSDVVKKPKLNQHGQRCFTCIDCSTTFDYQSHTSCITEAEKYQKALYKGKK Picst3 SFSCECNDTVVKKKLDQHSQRCFSCIDCSTTFSYRAHTSCISEAEKYEKALYKGPK Plicr1 HFHCFCGDVVKKPKLDQHRARCFDCIDCSTTFEYKGHTQCISEAEKYQKALYKGPK Polpo HFSCDCGHVLKKAQVSTHTWKCYSCTQCGERFDYTKHSVCMTEEEKVMGKYYKGPK Pucgr2 -------------------------------------------------------- Punst1 SFQCECADTVKKPKLDQHRARCFTCIDCSKTFEYKSHTSCISEAEKYQKGLYKGSK Rhior3 ----------------------------------------MTEAEKFQKHKYQNKQ Rhoto1 SFSCECGDVLKKGKLDQHAGRCYTCIDCNTTFSYRSHTSCITEEEKYQKSVYKPPK Rozal11 -------------------------------------------------------- Sacce1 TFNCECNDTVPKKNTEKHYYRCYTCIDCSKTFSYKNHTSCISEDEKYQKALYKGNK Salro -------------------------------------------------------- Schco3 SFQCHCGDVVKKPKLDQHSSRCFDCIDCSTSFQWKPHTSCITEAEKYQKGLYKGPK Schpo1 SFCCECQDIIKKPKLDQHRSRCFTCIDCNTTFDYRNHTSCMTEAQRYQKGLYRPTK Sorma -------------------------------------------------------- Sphar -------------------------------------------------------- Spipu1 -------------------------------------------------------- Sporo1 -----ATEVIRRSKGTTRVVRAVT-------------------------SVYKEPK Stehi1 SFQCDCSDVVKKPKLDQHRSRCFTCIDCSTTFQYKGHTSCISEAEKYQKSLYKGPR Tapde11 TFSCDCNDTVKKPKANQHAQRCLTCIDCSKTFDWSVHNSCISEAEAYQGALYKPTK Thetr FFVCSCGDCLKKSAVDKHCYRCVSCMDCNSTFDYKSHTKCISESEKY--KFANGRK Treme1 -------------------------------------------------------- Trire2 -------------------------------------------------------- Umbra1 SFQCDCCDVVKKPKLDQHRQRCFTCIDCSTTFDYKSHTSCISEAEKYEKSVYKGPK Ustma22 -------------------------------------------------------- Walse1 ------------------MNRCVDCIDCSTTFTAKSHTSCMTEEQKYQKNLYQKPN Zygro1 TFNCECNDTVPKKNTEKHYSRCYTCIDCSKTFSYKNHTQCLTEDEKYQGALYKGKG [Cluster3874.fasta_al_trimmed; alignment length = 434] Allma1 FRAVA-AVPVITSARFVTTTWTVRDTQRKRTLHQTLAVQRTASVEV--SDAHGDFYSGTQLVYVAERAFTYEP--DGEAYWGKRPVLVHLPSKPTFILILLVGYWGLVYCPNRLARLYTLAARYPVLRTKAV-YLSMPVGGPHNACSALRVVVPVVFPGLFVDALTPTIYATTAWYSIDL-AT--GHVEKVSYRVLHVG-ILAVESALDQPPRLVRLGEDGEVTVEQAIV-VRQKPL--ILLPHGGPHSVSANEWGHTVALVNYTGSTGFGNGSIYALVGKIGDLEVEDCVAKSLLAYLGGSHGGLIGAFLIG-RYPGFYRAASIRNPALNLGTFSG--TDIMDWSFAEAALPHDTYARMWTHSS-YSVISGVETPTLMQLGKKDARVPN-HQALEWIAWMRGNKPVRTLAFDD-SGHALD-SMDAAFFAEFRV Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 ---------------MIRLTSSVRDHTRKRGLFKHLAYLREASKEV--TKVHGEFYSETALVYTAEAKFRYIP--SGERLQNKRPTLFVLFGQALFSALIARGYLGITGCTNRPCAIWKLSARSPRFESKVV-WLANQVGGPHAGCSSLKEVIAVVFPGLFADYIAPSMAIHGVWGSIALSGPDVGAVKELSWTLLATKRLLCARSSPVTAAELVLLEDAGTASIIEVIV-VRRKPC--ITTPHGGPHFIFTTEFGYVVSLVNYTGSLGHGQHFIEKLLGRAGELDVEEASTQHLIKIIGGSHGGFLGAHLVG-RYPDFFSAVSLRNPVVAAGDMVS-VSDIPDWCFAQFA---DQYASMQAASP-MAHVANIKAPVLLLVGDADARVPM-TQAKSLYHALKARNDVDMFLFPG-AGHALD-GVEADWFAKVVK Batde5 YQQMA-SIKSYASATIVSMITSYRDFDRKRKMLSNLLTSRTT-IEV--TKKHGDFFDETKFVYVSDRDSKYVESMDGEGFTGKLPTLVFVASQAIMLPIIFNGIFGILYCYNRRTAIYSVNGRYPQLGSAFV-YLSHKVGGAHSACNTLSTLVQLVFPGLFVD-HLIFAILQTSWRCVNA-ST--GQVHRISYVLRSVGWILATRSLANEPHKLVL---FETVSTVQVLM-LMPTPL--VVMPHGGPHGVISTGYGFAVAQVNYSGSTGYGDDFVQDVVGRIGELDLADAAAYWASTLFGGSHGGFITAHLLG-FEPDFYKAGVLRNPVINIGAMVA-TTDISDWCFAEAGLAFQEYEFMFRHSP-ASVVHKIKSPVLLMLGAGDRRVPP-SEGLRWSQYLRGAGDISVIMFPS-VGHALD-SFEAEFLLKHFG Botbo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel YGDLA-QIPIPTQGRIVTTTWDNRAMQLKLTRQQRVAQLLTADLST--QKKHGTIHGEGHVLYVAERKFELTE--SGEQNDGVKPVICIVPSYTKWAPVVFFGLLGRIYCNNRRGNLYYYSAEELQFGNTLV-WFQRAADGPHQAVLEMRIIVPIVFQGFTFP-QTARLILSSSWCSVNI-AT--GNIEKLTWSLLDVNEVLAVVSAPNRPPNVLLLPGTGSWEFVEGIL-IVPNPM--VVNPHGGPHGASMASWGYAVLQVNFRGSLGFGDDFIRALPGNCGDMDVKDNAVLTVLDLFGGSHGGFLVSHLIG-QYPGFYKSCVALNPVVNIATMHD-ITDIPEWCYFEGTGEYEQREKMFNSSP-IAHVENATTPYLLLIGEKDLRVVP--HYRAFIRALKARGPARVLTYPP-SNHPLD-EVNVEWFEKSLS Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow FARIA-SSSVTYPQGFVTTVAKQRDLERQRQFLRSFLVVRKYTVSS--DGKHEAVFDESSILYLAEAKYELVE--DGEGYSGKGPSITVLAGSVTDLGLVFVAYLGLRFCNNRDAILAAVNARSPRFTSSVV-YLENDIGSAHNACSRMSLLVDAVFTGIWVN-QLPYIVTDTAIGSID---TQSGAVIPLSWQVLAVNLILAAFSTPSLAPALWLIDPAQQVHMLEAVI-VSAAPL--VSYPHGGPHSVFP--LGYNLVLVNYRGSVGYGQSSINTLLGAIGRMDVDDLATRTALAAFGGSHGGFLSIHMTG-QFPDVYKVCAIRNPVVSLPLMVA-NTDIADWCFSESGVARQSAELMLKASP-IYHVDAIKAPTLVVLGASDRRVPP-SQGTGLYFALKARGPSKLLSYPE-NGHGIA-DVEAEWIQQHLT Catan2 YADVG-RIPVPTKARLASVSYSTRDPIAKRTFHQTVAALR-AGCNV--TDVHGDFYGDAKLAYIAEA---------------KRPVLVIVPSKPFFALVGFVGYWGIAHCPNRLSSIYAVAARCPVVNTARIAFLAVPIGGPHNTCADLTLAIPAV-PGLFIDSLTPAIVGTVHWRTIDL-LQ--SADQHSVVVMTQSGHALVAKSGIIRPPSVV-LNKFGDVVTIEAIV-VRPKPL--VIVPHGGPHSAYANEWGYTVAYVNYTGSSGYGKDSIDALIGNIGNLEVKEQVAERLIQFLGGSHSGLIGTFIAA-QYPGFYRAVVIRNPVTSLGTFTG--TDILDWSFAEAGLPHHAYAHMWSQSG-VSVIDKVNTPTLVLLGAKDARVPT-FQGLEWAAWLKGNKPVRVMQFAD-AGHGLE-SMDAQFFEEFRT Cioin YRELS-LLPSVHSVEVIDCVWEHNDLERKIKYRKSGAVLREATVDFVAENKHGLVYDGSKVLYIAEE----TPGLDGEQLVGCCTSLYIYIGKGLWSDIIVLGWIGLIYCKNRPSALYQLCVYSPIVGTKLL-YLQSQPFGPHRQCGKLSVLVDEVFNGMFME-SIPELIFTTNHRSFNV-NN--GDVRCLAWRVHKVDIIIASCSTPNTPSSVKVLSD--SWEVIESIL-LKPTGL--VVNPHGGPHGCYPTSFGFAVSRINYRGSTGFGQNSIFSLPGNISKQDVFDQVAEF---ITGGSHGGFLTLQLIG-QFPDYYSAAAARNPVTNIASIVG-VSDIRDWAFCVAGCKFDMYNTMLTVSP-IMHVDDVKTPVMIMLGEADLRVPI-SQSHEYARMLRARGTVRLFQYKD-NNHPIS-NVKDEWFNNYCK CocheC53 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 FEEAY-SAPTFTSATVVSVDYTTLQNDFKRSFANHMAILCSKSINV--SDKHGDYYDNKHIMYAAERRYQFEG--DGVSYIGKRPVLVVIPGQAQFLAIVFTGYHGILFCYNRPSGIYVCSVRSARIGKGLV-FLATATGGPHDSASELHTLVPIIFVGIYTG-QLPILIFTSVWRSFDI-QR--------SNAVLGADLVIGTTSTPAHPEILAIRDSHSDWRVIECIF-VCPQPL--IVYPHGGPHSTFTTTYGFGVLLVNFTGSLGFGLDAVLAQVGQMDTLTIKENAAVDIHNYLGGSFGGYTGALLAG-LVPGFYRGIAIRNPVIDIAANAL-TSDIPDWNWAEVGLEYETFAKMWRASP-ARLIEKIKDPMLLLLGAADSRVPN-QQSLSFYYRLRAANPVQCKVYPN-VGHPLN-TIEAEFFAASLK Conco1 HQKLN-SIPSISSGKI-----SEHRETEDIEFKTSFFIKRKKIIDL--TELHGRIYKGDKFAYIAERNKDLLE--DGETYGELCPAIILVY-------YF-TGYHGIVYCPNRPSDIYKLAYRSPRIGNYLY-YMGMSIGGAHNQCSSIEEIVPIVFPGVYTL-EFGFLLFNSQWRCLEI-NS--NEICSISWALLDVNYLLAKFSSPSKPGELVLINNKLKWSTLLIII-KNSKRL--IANIHGGPHSSNFVEFGFTILHINYSGSLGYGQAYNNKLIGKVGDLDVKDHSIQKVLEVIGGSHGGFLAAHLIG-QYPDTFKAAILHNPVINIGANIF-LTDITDWNFSECGIYYEVYSKLYSHSP-HQYFDSIKTPSLVILGDKDLRVPP-AQSIQ-------------WWFHIRKRHPLQ-SINKF------- Conpu1 FNELF-ELPVPTTGTFLRVAYSFRDRERKRSQTKTFALLREASLDV--TEKHEEFNSETALLYSAEAKFRFTP--HGETMYTKKSTIYLFFGQAVFASIIATGYMGVKFCYNKPTALYELTVRTPRVATHLF-WLSNALGGAHNASATLKALVGPVFPGIFAD-DIAQVVISSGWGAVDA-SS--GAVKELSYGLLCTNRVVCSRHSPTLPPEVVLVDAKGEYSVVEAIH-IGPKYS--LLMPHGGPHANSMVTFGYTLCSPNYTGSTGYGENFVQGLIGNCGSLDVEDAAARHFNDIWGGSHGGFLTGHLIG-QYPDFFRAAILCNPVISLGE-IS-TSDIPDWYYAECGLPFEMYAKLWAVSP-ISYVDNVKTPALLCVGEADKRVAP-TQGIGYYHALKGRNVVEMLTFPG-ETHAMD-GVECAWIRAWTS Copci YTELA-EIPVPIGGQFVEITFSVRDHELKKTVVKTIVVLREASVDV--TERHDKFYTEDAVVYTAEAKFRYRP--DGEGLTGQRPALFIVLGQAVFSGLYATGYLGVKGCFNRPTGIWR-SCRSPRVEQ-LV-FLSSASGGPHVTTASL-EVIGIVFPGLYPPYNLPSLAFHSHVGSAGLDGK--RSGWDRSWSVLATNRILCWRSSPSVPYEIGVVRDGGRTSIHETLV-ITSTPC--VLVPHGGPHATTTTAFGFTLALPNYTGSLGYGEAPIRALVGACGRTDVDDGTLDHLVKVQGGSHGGFLSAHLIG-QFPDRFSGAVMRNPVISVGE-IS-TTDIPDWYFSEFGYEYQTFTQLQSASP-IHHVDKVKAPVLLLVGLADRRVAP-THGVEYYHALTARAKVELLTFEG-ESHPLD-GVEAAWLRALAS Croqu1 YTALA-SIPVITSATVIEVDYTIRDHVRKRRVTQAFVILRARCHEV--TEKHGKFIKESCLAYVAESKHRYIA--DGEQLAQIRPALFLFYGQPVFGSIICTGFPGLIYCQNRPTAIYELSGRSPRVGERVY-YISNPIGGPHGSCASLEVLVSVVFPGLYID-QLP-LVTSSIWGSIDL-QT--GKVQRYSCTVWNTDSILASHSQTTQPPIICLLAANGSTQVMEIVF-TSGT-V--IIAPHGGPHSTSVNEFGYSTAYINYPGSLGYGQKWVYHLIKHLGQADVESLALDFLRSVNGGSHGGFITAHLTS-RYPDLFAAACMRNPVVDLVGTAAGGSDIPDWSFAEADLPFEAFRVLKSASP-ISQLDQVKTPTLLLLGDVDRRVSH-QQGLAWYHGLQGRGKSNAYMFIE-NSHPLS-GIEAETFEHFST CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi YRELL-SIPTVNNAFFASIIVSQIDITNKFYMSQKTLTIKETSITS--KDIHKKILCEKYVAFIADSQFVFRD--DGETYSPVAPSIFILAGQVIWTPLVYVGWLGIRACFNRSSSLYHLCYRSPRFSSKLI-FLGFNEIYAHDTCSKIETLLDYKFPGVFCQ-SLPTFLFSTIIRSFNY-ES--KELKIILYVLYDIKKYLIGESSVNQPTKVYLLGSDKNATIHELIY-LKNKPLGCLVFIHGGPHSNLDVGYGYNIIIPNYRGSTGYGKDFVDCLPGYIGDLDVDDQAINYTLDVIGGSHGGFLSAHLS--RFP-IVKTSIMRNPVIDIPSMST-LSDIPDWCFFEAGINLEEIEKMRKCSP-SFHIENIKIPSLLALGDSDLRVPP-SQGLLYYRMLRERDPTKCLMYPK-TGHSLD-SIDARWLKKYLN Dmel -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 YSELA-EIPLPSTAQFVEVSYTIRDHIRKRTVAKSIAVLRKTSMNV--TEYHGEFYSETSILYAADDKFRYNP--DGEGLHGKRPVIFIFFGQAVFSPIYAIGYLGIKGCFNRPSGIWQLSCRSPRIST-LI-WLACATGGAHLATSSLNPLVGIVFPGLYPPYSLLSIILHSQWGSISL-AD--GTIKNLSWSVLATSLVVCSRSSPSVPYEIMLIDKSGKTTIVETIL-IQGRPC--ITSPHGGPHGGSTTAFGYTISFPNYTGTPGYGEAFLQGLIGRCGELDVQDAAARHLISITGGSHGGFLTGHLIG-QFPTFFSAAILRNPVISAGD-IS-SSDIRDWYFSEFGISYQIFATLQAASP-IAHVDSVRVPVLLLIGAADRRVAP-SQGIDYYHALRARYRVEMLIFEG-ESHPLD-GVEAAWFAAAQS Ganpr1 FNALA-TIPSVSSAQIIQVTFQQRDLSSKKKYSQTFTQARISSINV--TTFHDDFYDDDTIVYVAQRKYAHAP--DGEAYTGKRPVIVVAPGQPILV-IVFHGLNGALYCFNRPGGIYKCGARSPRLGDTVV-FLSNPVNATHNSCATLRVLVPPVFPGLYVD-TLLFVILVTPWRSVDV-QS--GEMGKVSWTVLDVDAMVLLKSEPNSVGELFLLTPGNSYSIFESII-LHPPPL--VVVPHGGPNSVFQTEWGFCVVLVNYTGSIGFGQESIDSLVSHIGSLDVADSVALH-LTLYGGSHGGFITGHLIA-MQPEFYRGAVLRNPVANVGLLAQ-ISDIPDWGFECAGIPYQHYAAFWVKSP-IAGVKKVQTPTLFMLGETDRRVPN-PDGLAFHNHLRARG-SYLCTFPG-TGHPLD-SVEAEFFV---- Gloin1 FKLLA-TIPTYAGVKTIQVILSQRDLKRKRLIVKQLLILRCQSIDV--TDSHGDFYNEEKAVYIAERKCDFVP--GGEKFVNKRSVIVIVPGQVFFGPLIFNGYYGIYACINRLVGIYQTHARSPRLEKVLT-YYSNPISGPHSYCSELRVVVPIVFPGIYND-QMAFLIIQSCWRSINL-DT--GKVQDLSWSLFIANYIIASRGAPNDFPELYIVTGYQTWSIIEVIY-VKPNPL--IVCPHGGPHGVITADIGYVVAIVNYTGSTGFGQDSIDALIGKAGDLEVKEASAQYFIDVMGGSHGGFISAHLIG-KYPDFYKACVMKNPVLNIGGMAT-ITDIPDWCFSEIGLPYSDYKLMYENSP-INNIDKVKTPTLLMLGSEDKRVPH-NDGLNWYYYLKGKGEILCKIYKE-TGHALD-SVDAEFLEEKIG Hisca1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 YTTLA-EIPVPTSAQFAQVRYSVRNHVRNTTLIKTIAVLREASVDV--SERHGAFYSELAIVYTAESRFRFQP--DGEGLDGKKSTTFVLLGQAIFSPIYGTGYLGLKGCYNRPTGIWQVSCRSPRSST-LL-WLSCKTGGAHISTSTLDPIVDVVFPGLYPSYNMPHILISSAWGSVSV-KD--RSVRDLSWSILAACRFICSRSSPSIPYEIILLNDDGRTSIVETIV-VQS-PC--ITVPHGGPHGTTTTAFGYTLSLPNYTGSLGFGESSVQALIGNCGALDVQDASINHLIDVMGGSHGGFLTAHLIG-QYPSIFSAAVMRNPVISSGE-IS-TSDIPDWYYSEFGFDYETFSKLRAASP-IAHINNVTVPVLLLIGNCDRRVAP-TQGIEYYHALKSHFAVEMLVFEG-ESHPLD-GVEAGWFKNCKS Lenti61 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 YVKLA-SIPVVTAASVIEVDYSIRDHVRKRRCSQAFIVFRKFCKEV--TEAHGKFIQEACIAYVAETKHRYVP--DGEQLDGIRPALFLLYGQPVFGPIFCTGFMGLIYCQNRLTAIYELSARSPRVGNHVY-YISNPVGGAHGSCAALKVLVPAVFPGLYID-QLP-LVTNSIWGSIDL-SS--GEVQRYSCTVWNTNCLIASFSQTTQPPVIWLLAQDGSSQVFEIVY-TMAKVV--IIQPHGGPHSTSVNEFGYSTAYINYPGSLGFGQKWVNHLINHLGVADVESLALDYLRAISGGSHGGFITAHLTS-RYPDLFTAACMRNPVVDLVGTAAGGSDIPDWSFAEANLPFEAFKVLKSASP-ISQLHQVKTPTLLLLGDVDRRVSH-QQGIAWYHGLQAQGPSKIYMFPE-NSHPLS-GAEAESFEHFSS Mnele -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr YAKAA-TWPVVTEGTVVELAVRQRHLATKLESTTTVSSARIHSLEV--THLLDYVYDALHYAFVAEQTFLARE--NGEGRAKVMPVLFLFPGQPLFLNLAMVAWPGILYCANR--------------------------------------------------------------------ESR--------------------------------------------------------------PHSAVSCGFGYGILLPNYRGSLGNGTAAVASLVGKIGQQDVADACLDEVQAVFGGSHGGFLTAHLSG-RFPQRFQSATLRNPVIDVASMIC-ATDIPDWCLVECGIPEAQWEMLRQASP-LQYAGAMPAPTFGAKGGPQKKKPP---------------PSKAKMFSK-SAASLS-GLSAKSATKTQS Morel2 FKALS-AIPSYSGATIIQVSYSQRDLERRRKFTRTVVTLRSHLLET--TALHDDFYDESKIVYVAERKYNYKP--DGETFTGKRPALVVVPGQAIFSHLIFTGYFGIVYCQNRLTGLYQVSARSPRLGSTLV-FLSNTVNGPHASCAKLSTVVDIVFPGLYID-QLP-IFVSSSYRSIDV-HS--GAIEEL--SVLFAKWVLTTYSTPTEPWILILFEKNNSWSIVEAIF-IEPFPL--VIFPHGGPHSGFAAEFGFAVANVNFTGSLGYGQDSVEALVGRVGELDVNEAVRDHILSVTGGSHGGFLSAHLLA-KDPTGFKAAVLRNPVTDIPAMAN-ITDITDWCYAVNDLPFEVFKRLRAASP-MEHVEKVTAPSLLLIGAGDRRVPP-SQGFSWWQARQNKIVNRIQVFEG-TGHALD-SVEAEFLVEFTR Mucci2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mydma FRE-A-VLPTVSSASVIETSWTQKCFDR-RSASFSFLIIKEKSINLSACEKHGNVLDEDKIVYLAERKFNYEE--SGEQMTEVIPVICVAPSQPQWGPIIFEAILGIIYCSNRASYLCSVSNYCPRVQTKLI-YIHRNLGDPHQGVEKL-------FP-LYVY-SLPSVIIPNLEQAINT-ETR-KIIKKV--TILDVIAILSHMT----------LDSTECQSTVESFI-----PL--IVWPHGGPHSVICNNYGYIVLLVNYSGSTSFSEKSLMSLPGNIGSQDIYDNIALNFISVFGGSHGGFIGAHLIA-QYPDFYCAAALRNPVIEIASMSV-TSDIPDWTYAVSGLSYEVYKVMLEKSP-VILADKIKAPVLLCVGSKDARVPP-TQSIHFFKLLKSLNDVKMLMYPD-DCHPLS-NIETEWFYQHKR Neucr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 YQELA-EIPTPASASFIRLDLSIRDHVRKRSITKTIANLREVCHDV--TKAHGAFYSETALLYSAEARFRYTP--QGEGLQGKKPTTYLMLGQAVFAGAFATEYLGAKWCYNRPARIVS-SNRSPRVST-LF-WLSNDLGGAHASCTSLSTILDKIFPGFYPDFVLPHVVTQSTWGSISA-ST--GAVKNLSWAVLSADQVICTRSSPSIPPEVVLLSKSGQGSIVETIV-LRSVPC--ITMPHGGPHMTTTTAFGYTISSPNYTGSLGFGERYIRKLLGACGTLDVQDASVQHLIKIQGGSHGGFLAGHLIG-QYPDIFAAAVIRNPVISCGE-IS-TSDIHDWYYAESGLPFETYATLYAASP-IAHVDAVRARVLLLIGEVDQRVAP-TQGINYYHALKGRGPVEMLCFPG-DSHTLD-SVEAAWFEAVRG Polpo FKELVYNIPSVDQAIFVSIVTSVTDLQNKYYLHSRSLTIKERTITS--KEIHKKIFCEKYIAFIAERSFLFKN--DGETYVSYQPSIFVIAGQVTWTQLVFVGWYGIRACFNRLSSIYYVCFRSPRFGKQLI-FLGMPGVLPHNSCSQLTTLIGEKFPGIYCQ-GLPTLVFHDQIHSFNI-ET--KELETL-CTIFDVRQVLIGESTPSSPTTINLL-KDKQWDIEQIIH-VQPKPL--ILFPHGGPHVGSTCEFGYAVTMINYRGSTGFGRDYNDVLPGHIGTMDVADATLDHLLTVMGGSHGGFLAAHLCGLKTP-RFKAAVIRNPVIDISTLST-LSDIPDWSFCEAGVKLEELIKMRECSP-ISHLDNMNVPILLGLGENDLRCPP-SQGMMLYNALQQKGPTKCLYYPK-TGHGLA-SVDAKWLKQYC- Pucgr2 YSQLA-SIPTISSGRFIQLDYSIRDHGRKLRARQSFAIFRTVSHNL--TSIHQSFLSESQIAYLAEIRNRYVP--DGEQLTGIQPAIFVAWGQPVFGPIFCTGFLGLIYCQNRPSTIYRLSARSPRVEGKII-YLSNPIGGPHASCASLKVLVGPVFPGLYID-DLTSIVTSSIWGSIDL-RS--GEIKAHSCTVLNTQQVLCVISQTDSSPQVWILEEDSKSQIIEIVL-TSPTSL--IILPHGGPHSTSLNEFGHSIAYINYPGSLGFGQKWVEDLPKRLSVADVDSLALDHLLSVNGGSHGGFITAHLTS-RYPELFAAACMRNPVVDLVGTASGGSDIPDWSYAEANINFIDFKILRDRSP-IKFIQNVKTPTLILLGNQDRRVSN-QQGLAWYHGLKSLKEAELVLFED-NSHPLN-SIYAEWFEFLDS Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 ASELF-HLPTPTAAHWLHLTLSQRSLSSKRTLTQSVAVFRVCEVECK-SEVHGDWYSFQALVYRPSKKFVYTA--DGETFTGKKPRLFLLYGQPSFLPLVATGYLGIVYCTNRLARVWVLSSRSPRVSAQIV-YLSNILGSVHASCAQLRVLVKQVFPGLYVD-QLPSVVAASSWRSISL-TT--GRVTSLSFNVLGTGRVVAVRSGCGTVGRVVVLGGKGSYTVLELIL-VSPIPL--IVYPHGGPHSTYTTDFGYRLVLVNYPGSTGFGQHTISALPARLGEWEVEAASAHYLNALMGGSHGGWIACHLSA-RWADEWDAVVMRNPVTDLVGNAG-MTDIPDWCYEETSTPYSTFNTFHSLSP-LRHASNVTAPTLLLIGESDRRVPK-DQGRAWFHALKGEGEVEMLVFPG-NGHPAE-TVEAEWLAKYTD Rozal11 FKQLS-RIPRISEGVI--VKLTYKD-HFNKKIEKSVAIFKD--------------------------KFEFSD--DGEKFQGKAPKLGIFVGQPVFGPVLFMGVYGFAFCYNRNMHIYQYSARSPILSSFFI-FLGNPIGGPHFSSSILTIIVNKVFPGLFVE-RLSLIV-------VDV-AS--GQVERISSCLLDIDLIISSDSSLNSCNEFVLLNNKS-----HVLI-LQPQ---------GGPHSSFVNEFGYIVAL----RSIGYGQKTIDNLVG-----------------IIGGSHGGFLGAFLTA-KYPDLYKVCILRNPVIDISNNGA-FSDIPDWSFAEAGVEFTHFEHLYKSSP-ISLVDNVKCPTLLLLGRNDRRVPI-YQGLNWFYQLKSKGKTKLMMFPD-TGHSLD-SMDAEFLCENME Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro WYRRA-EVPTVKGGSFVVLGHNIPDAQEKRTYRRTLFAFTAATADC--KKLHGKVLDEETVYYVAVTEKHTLS--TGEAHVGIGTAIFRWGEVAVRGQ---MAFLGAQYCINRNTAVYVASCLAPRFGARVV-WMQTNADGPHRRASAVTTLVP---PTVYIG-KLP-FVFSHLTRSVDC-AT--S---THAWSVQDVRNVLVSFTCPSTPRGLFVASSDV---LVT--------PT--ILVPHGGPHSAVPLDYGYAIVFPNYRGSLGFTEDTLESLPGKAGTQDVEDLAYKNEPSVFGGSHGGFLTAHLTA-QYPDKFVAAAMRNPVTDIAAMVH-VTDIPDWCFVEAGLPIEDMAAMKKASP-LPFVHRVKSPTLVLIGDKDLRVPP-FQGRLWYYGLRENGETKLFTYPD-DSHPLA-SIACAWFGRFR- Schco3 FVELG-SIPVPVAGRFVQITYSVADYARKRSTSKTIAVLREVSHDV--TDAHDAFYSETAVVYVAEAKFEYTP--PGERYPGRKPAVFILFGQVLFSPLYATGYLGIVFCTNRPSGLWQLACRSPRISRQLY-YIACAVGGPHASTTSVELVLDVVFPGLYPDITLPYIVSTTAWRSISA-ED--GTVKDLSWAVLATRKIIGVRSALSIPYELAVLNDTGTTSVLEGLVHCASSPA--ILEPHGGPHATAVPAFGYTVLQPNYTGSLGFGEAAVRALPGNCGKLDVENATLRELIKYTGGSHGGFIGGHVVG-QYPDLFAASILRNPVISAGE-IS-TSDIPDWYFAEFGVDYETYARLHAASP-ISHVEKVRTPVLLALGDSDLRVSP-TNGLGYYHSLRAHARVRLLMFPG-MNHSLD-GLEESWLAKWGS Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar --MLA-EFPDID--------------------------------------------------------------------------------------------EAIVYC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSHGGFLGAHLIA-KYPDVYKAAVLRNPVTNLVEEVS-TADIPDWVYAEAGL--EDLDKLYALSPISNDLSKIKTPTLLLLGAKDRRVPP-SQGLQFYRGLQAAGKSKVYWFPT-QSHPLW-YHDAL------- Spipu1 YKSTA-TLPSFSASHIVSTV---RDLDRRTRLFTELVVLKSKSIEV--TEKHGDFYTESTVAYVAERKFKFKP--DGEKFTKKAPAIVLCVGQVLFGPLIFWGVYGILFCPNRLSGIYQTSARSPRFRKTLF-YISNPIGGPHFPCGELRIVLPEVFPGLFVD-RFAWIITHTNWRSVHA-ST--GKVIDLSWTLLGVNWVVAVRSDPGTPHEVHILQ-FTTYDSREAIL-LLPSPL--LVYPHGGPHGAFTSEFGIGIILVNYRGSIGFGKDGVDCLVGRVGDMEVEDFVAEQVRTIWGGSHGGFVSAWLIG-KYPDYYKACVLRNPVINMGSNLA-QSDIPDWSLAEAGITYEIYSKIWPKSP-ISVAQHVKTPSLLMLGENDRRVPP-YEGMNWYYYLKGRGDIRVMTYPD-NGHALD-GVEAEFLVEFIG Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 YKSLT-GLPSYTSAQFIIVTSSVQDHLRKRSFTKTLAILREAQLEV--TSVHGAFYSETALVYTAEARFRYVP--DGESMTGLKPTLFVAFGQAVFAGVVATGYLGTKGCFNRPSAIWELSARSPRVKTTVF-WLAHVTGGPHAACSALTSLIPIVFVGLFPDSGLPYLITPSAEGAIDADKP--CSVTHLSWNVLGTKSVLCWRSTASHAPELVLVDASSKVSIVETIL-IEHGPL--ITVVHGGPHGSNQASFGYTVSLPNFTGSLGYGDEFVQQLVGKCGTLDVDDASIKYLLEVQGGSHGGFITGHLLG-QYPGFFSAAVLRNPVIT-PE-PS-STDIPEWYYYEFGLPFSEYGKLWPMSP-ISHVDKVKAPVLLCLGLEDRRVAN-THGMAFYHALKGRGDVEMLQFKG-ESHPLE-GVEASLFEKHRI Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr YTAIS-AIPLATSGRIKSSTTNS-----------WFEIARK----------HGDIVDASRLVWVAEPKYEFSE--DGEVNTGVAPQLYLLLGQACFSPLVFGVVLGLVYCSNRAIKLYAVRAEAPIFGDELV-YLARTLARSHRCAAAVS------FTGIYGD-SLALLVT-TLVRSIDL-AAATATVLP-TCTLL--GHVLVASSSPATPSTVFILD---TTELVAHLL-YSEA-L--IVNPHGGPHSCYPDSFGYAVIKPNYRGSTGFGNAFVAKLPGHVGDMDVADAATAHALALVGGSHGGFLSGHSAL-RFGGTYAAAALRNPVTNIATMLG-ATDIPDWCW-------AA----FAASP-MAHVAASSVPMIIMIGLNDRRVPP-PQGTELYYALRARGAARLLHYPD-NTHALN-KPAAAFFDDVLS Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ustma22 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 --------------------------------MSQSLFSQ-------------------------------VE-------------------------------------YDERTK---------------------------------------------------------------------------SWVLQSV---LASNK---------------------------PT----IILPHGGPHAAMTPAFNITVVMPNYRGSTGFGEDYLKELLGNVGTYDVEDAAMDMTEKVYGGSHGGFLAAHLTA-QYPTRFKTAIVRNPVISLATNST-QSDIPDWCFVESGIPFTQYGKMDDVSP-LKLAQNVQAATLLLAGADDQRVPN-QQTRHWYHALRNHQDVDMLVFKG-TGHPLD-SVEAEWFEKYFK Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3875.fasta_al_trimmed; alignment length = 216] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 LLASAPTVVASSWGFTVSVQTKGAKEKIPLSKPVALGSSDTLKVILTASSAK--RAHQVFLLLRDPKTFTV-KDNGKSRLELTQKDLPVQFLSVPLDARLVIGAFPLIVARNRYGKLPEIHHIFK--SDPQSPPVIVTLVFIGMVLA-AFPVLGGLWLFIGVNIPHAVFLGSLVSIEWIFFLYYSHWTLFQILAAAGVVAFISGSRALGEVQGRRL Aurde31 AQLATSV--VRDLSIRFTIFTEGSAGPLSVSPPLNLTAQDTLKLTFSVDVADNAKPHQTFLRFYDPVTVRV-KADGKAKFDLNMAKPPIALPATPLQVWLVLGLFELYLPRTSFHPLPAIHHTFR--PDPKLPPRIISLVFAGAVLA-PWAILLALLARIPHPPKIAPFVALLAAFEALLFTYWLRLKLPDVLAILAIPTVAAGKRALSATVQWRL Batde5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Botbo1 PLLSLAV--RAALSIKVSINSAENSEALRLPDPVRVGATDTLKISFIVDTGKPVQPHQAFLRFWDGKALRV-DTNGKSKFELNMRRPPPSLPATPLNVSLILGLFAAYLPASTFHLQLEIVHTFR--PDQKHPPKLISAVFAGVALA-PWAVLFYLLSYLPITLSTAPFVALIAAFEGLLLWYWADLKLGQVLAALGLVTAAAGKHALGSL----- Botci1 VLAGAVT-AASSWGFIVSVSGKSAKDKLSLAKAVSLGAEDTLKIVLTARAAK--RPHQAFLLVRDQDTFSV-KESGKGKVDFSQKDLPIQLLTSPLRATLVLAVFDLALSLDRYGKLPEINHIFR--ADPQSGPKIFSLVFAAAVLA-TVPVLLGAWAYLGANISHALFYGSIIAMEGIFFLYYSSWNLFQTLGVVGLVAFLSGSKALSEVQSRRL Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 LLSSAVS-AASSWSFTVSVTSKGAKDSLSLGKSVSLGATDTLKLVLTTGTAK--RPHQAYLTLTDPVTFSV-KDSGKGKVDLSHKDLPHQFLTAPIAASIVIGVFDLNVTRDRFAAEPEIHHIFR--SDPKSPPKVITLVFAAAVAA-ALPMLLGAWAILGANVSHALFYSSILAMEGIFFLYYTTWNLFQTLAAVGIVAFLSGSRALSEVQERRL Coere1 GVLAGSSLVNGAVVVKVRVMERTGEQSVELESVPKVKASTPLVVTFSAQEGKALRLDQAMVNLQHTETARA-VTEGSYKMDITRKDFRRHFAAAQYHVALVLGVGNIEMAGGTYGPKSEIHHRFS--EPQQMPNIIVSLTFTALTVA-PLVVLLQTWTGLGVNAGSVVFMALIAAYMGLAVAYWVGLKLFPTLLALALPTYLAGQHALSKRIESKT Conco1 YFTSVST--GSGIELKLSITDSTGTEKLTLSSPLQLETSDVIRLSYKLSETKEYSYHQ----------VQTSGKVGQFKLNLPYKSLSKNIKAQNFNIYLLVRLASLSLPESEFGPLPLIHHTFR--PDEKVPLKALSLVFSGLVLA-PWALLLVGWTSNSVNVYNAGFIGTLVAYTVLNYLYWTKLNVFETITIITLFSVPFGYLTLKNHN---- Conpu1 WLLAAVQ--AAKIAVKVTISGKGATETLS-SESLTLGPTDTLKLTFQLPDGKGVQPHQTFLRFYDAASVRV-SSGGKAKFELNMAKPPPSLPPTPLSVSLILGLFDLHVPASQFAPQPEITHTFH--APQALPPRPVSAVGTALVFA-PWVVLVGLMSRISIPTETLPFTILLGAFEGLLVWYWVGLRIGDVLAVLAVPTVFAGNRALRATGRWRA Copci SLLA-TQAAASSLTLKVVVADNIGAEPFSIEKPVKLEGRDILKLTFQVEAGKGVQPHQTFIRFFDETTVKV-QPSGKAKFEVNLQKPPLYLPPTPLQVSLIIGLFDLQLPRSTFHPRPELFHTFR--PEQKLPPKFVSLVFAGIALA-PWAVLVGLWSQVAPAPTILPFVLSLGALEVLLFWYWVKLKLGQVLAILAIPTLLTGKQALSNISGQRT Croqu1 -FLAAALV-SADFVIQLAVVDSSGTLEVSSVKTLSLSPENTLKLSFQIKESKGIAPHQVHL-------VKV-RGANKAKWELDMARAPTDFFSLNIKLELLIALATLKLAPS--LPQPPLEWTFR--APRKPINPIFSLAFTIIALS-PWLILLSAWSTLANCPSTIIFLATIASQEILILTYWSSLRLYQYLFFLSLPLILSGRTALSELRARRK CryneH991 L-LTAVT-AKGTLGIKVAVTSPDGTYTLKLPSPIALSENTNFKLAFTVTSGESMYPQQAHLLLEGLQSITV-KSNGKAQITINAAKPHPALLTTKFHLTLILSLGELSIPESAFQPEQELFHTFK--EDPKTVGWTKSGAGIIVTLA-PWGVLFVFFGKLLPSVSSYVFLLVLAAIETLIFIYWVGLKLYQLLLALCAIAAYSGLIALREQRERRL Crypa2 LLLAAVQ-AASSWSFSISISNKKTKESFGLKTPVSLSAQDTLTVSLTAGKAK--RPHQAFLLLTDQSTLSV-RDNGKGKVQITQKDIPAQFFVSPLHASVVIGAFNIEIKPDRYGKQPQIHHIFR--EPTKYGYKIISIAVSLVIAA-TLPVVVGVWLLHGANVSYATFLGSIVAMEFVYFLYHRGLSLGHILAVLSTTTVLSGMRALGEVQSRRL Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 PILAAS---AAKLAVAVSVLSSEGAESYVPSTPLALGPTDRLKLTFSIKDSKGVQPHQTFLRFYDETTIRV-NSGGKAKFELNMARPPPSLPPSPLHVSLLIGFFDLSIPPSTFHPLPEIHHTFR--PEPKSPPRFISAVFAGVVLA-PWLVLFTLLVQIPHKPQILTFVGLLGAFEGLLLWYWVALHLGQVLAILGSVTILTGNRALNSLAKWRT Fusgr1 LLFLTAS-AASSWGFSVTVASKQGTAKFSVKDTLILGKADTIKVSLTTSEAK--RPHQAFIVITES-TLDV-KSSGKAVASISHKDISVPLLLSPLKVNLVLGVFNIQIYHVRYGRREEIHHVFK--VGETSPPKIISIVFVTAIVC-TFPLLLVGWSKLGANISHALFVGSIIAIEGSFFLYYVKWNLFQLLAGLSIVAFLSGVKALSEVQGRRF Galma1 LLLA-AQ--ASILTLRFTVSDSTGSEPLSVSTPVKLTGKETLRITFQVESGKGVQPHQTFLRFYDEKTVRV-TPGGKAKFDLNLSKPPLSLPPTPLKVTLLIGLFDLVLPRSTYHPLPEIKHTFR--PDNKLPPRFISAVSAIVVLA-PWVVLLGLWSQVAPRPSILPFILSLGAFEVLLFQYWVGLKLGQVLAILTIPTVFAGKQALSSIGKRRL Ganpr1 VLLAVAPAQVDEQTAEVVVDAVAGEPAATAPTPVQVVGDDVQRITPPASAADASLPHQAFVVFRDAKGLAATQGDADGKYTLDVD-FSNDKTRATYTLTVLLGL-------NAVK--PEIRHVFR--PPQKLPPSIVSLAATAAVLVVPWGFLLWAWSSL---PHAAFLVT-LGLFYVLLWAYWTVLNLGQLLAVLTPVTALTGRLALSEVAARRT Gloin1 LLLCTSAQESSERSFKLAVTTSDSTESVELDKPIELSHGDNLKIIFSLETKKGIQPHQSMIILSSKQTVTV-RDNGKARAELNMLDIPENLFLGSL--NLIIGIGTVNIDVPKYGPKPEIHHIFR--PDQKLPPTIISYSFVIIVLL-PWLFLIGAWIHLGVNV-IISFLFTLLAIEILFYNYWTHLNIFQTLSGLSILAFLSGQKALSDVQGWRL Hisca1 LLLSASSWAASSWGFVVSIAQTGAKQKLSLSKPVPFGESDILKLSLTTVAAK--RAHQVFLLLKELDSLSV-RESGKANLELAQKDLPTQFLQSPIKANFVIAVFQLDVIRDRYGKREEIHHIFK--ADPKSPLFIITLMFIVAVLA-GFPTLAGLFFYLGVNISHIFFIGSIVGLEGIFFLYYTTWNLFQTLLAMGAVAFVSGSRALSEVQDRRL Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 SLLA-AQ--ASLLSLRLTVSDSTGSETISSQIPVELAAKDILKLTFQVDSEKGVQPHQTFLRFYDEKSIRV-TPGGKAKFELNMAKPPLSLPPTPLKVTLLIGLFDLVVPRSSFHPLPEIKHTFR--PDQKLPPRPISAIFTVLVLS-PWVVLLSLWTQVVPIPNVLPFILSLGAFEGLLFWYWVDLKLGQVLAILSIPTFFAGKHALSNIASKRL Lenti61 LV---VQ--ASVLTLRLTISASDASEPLSPTPPPTLGSTDVLKLTFQVEEGKGVQPHQTFLRFYDPVSVKV-TAGGKAKFDLNMARPPASLPPTPLKVSLYIGLFDLVVPPSSFHVRPEIVHTFR--PEQKVPPKFISAVFTLFLAA-PWVVLLGLWAHIRPQPSILPFIATLGAFEALLVWYWVDLYLGQVLAILSIPTALTGKRALAAVGDWRL Malgl1 -------MTVSALSYRLSVSSFDGKKSLELT----MEPDDVVKLTFYA---RELLPHQAWVVMHDVETLQVRGSSSSVSWSMRIDRLSTAL---TFRLSLLLAFLDVQFAHAGFFPIPLHEHMFRVEPWQTMPPSSLSLGVALIVFGLPWALLLH--------TSAAVLLSCVWAMEVLAFLHWVGTPVRIVFGVAMLVALIGGRASLSETWIYRG Mellp23 -FLAAASV-TCDFVLQLVVADGSGKVDVSSNKILSVTSENVLKLTFHIKDSKGLTPHQVHL-------VKV-RGAGKAKWELDLARAPTDFFSLKIQLEIVLALATIQIPSNKYAPQPPIEWTFR--APRKPISPIISVAYTVVVLS-PWFILLSAWSTLSSATSTIIFLATIASQEVMILTYWTSLRLYQYLFLLALPLILSGRTALSELKARRK Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 LLASLA--IAESWKVNLIIAAPGGEHKLEVQD--TADSTDVFKFSFKIE-----KPHQAMVVFQSQDEASV-KSSGKGRFDLNFNKADAKFKYGKYAMTFLVGLGNIEVKGPDYQAQPEIHHQFR--SDQKLINTAISGLFTFLVLT-PFAVLFFLWSKLGIKINAVVFFGSIAGIEFVFYNYWTHVTLFPVLGGLSVVAFISGRYVLSAVQTRRL Mucci2 AFTAFAAGEEDV-----------------------------------------------------------------------------------------------------FELQHEIHHVFR--PAEKMPPASFSKLFTLVTLS-PWLVLIGGWLQLGITVSIAAFVTSLLAVEYLFYLYWTQLNLFQTLSGLTVITFFAGQRALSSIQSRRI Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 LLLAAAQ-AASSWSFSISVAAKKGKEKFSLTKPVGLGSTDTVKIILTAGKAK--RPHQAFVTIKEQETLTV-KDTGKAVVQISQKDLPVQFLLSPLKASVVIGVFDIEIQTDRYGKKPEIHHIFR--PDPQSPPKVISLFFALAVAA-TVPALFISWLLLGANLSHITFFGSIVAMEGVFFLYYTSWNLFQILGVVGIVTVLSGTKALGEVQSRRL Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 LLAAAPGAAATAWGFTVAVQPKGAKEQLALSKPISLFGADTLRVTLTASSPK--RPDQAFLLLKDAQTFNV-KDNGKSRVELSQKDLPIQFLSLPVDAHIVIGVFKLSIDRNRYGKKPEIHHIFK--DSASSPPIVITLAFVAMVGA-AIPALAGLWLFLGANLSHATFLGSLIAFEGIFFLYYTSWNLFQILAVVGAIAFVSGSRALGEVQGRRL Phybl2 ALAAHAAGNEDV-----------------------------------------------------------------------------------------------------FEMLPEINHVFR--QPEVMPSAWFSVLFGLLALS-PWALLISGWTSLGINVSIVAFLLSLASIEYILFLYWVKFNIFQTLFLLSIVAAATGQRALSQIQKIRT Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 LLLAAVQ--VSALSLQVTIKSSSSTESLSLAKPLTLGPTDTLKLTFQVEDGKGVQPHQTFLRFFDEVTVRV-TPGGKAKFELNMARPPLSLPPTPLKVSLLLGLFDLVLPASTFHPQPEIKHTFN--PPQKLPPKVISAVFAGLVIA-PWVPLLAVWGQIGPKPSILSFTTLLGAFEALLLWYWVDLKLGQVLAILAVPTALAGNKALGAIGKKRE Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 AILALPSG-SAELVVQLVVLDVNGSFEISLAPPFELNDENTLKATFEIQAGSLFSPHQVTL-------VKT-RSKGKAKWELDLARAPTDFLSLEVRLELIIGLATFKIPKSKHYIQPELKWTFQ--PPRKKDNPIFSLAFVGIVAS-PWLFLLTAWAKISQNLSTLLFILTMVSQEALILTYWARLKLYQYIFLMSFPLILCGRTALSELRLRRK Punst1 ---------------------------------LTLGPSDTLKLTFQVEDGKGVQPHQTFLRFYDEQTVRV-SSAGKAKFELNMARPPASLPPTPLLVELLLGLLSLTLPASTFHPLPPIAHTFR--PEQKVPPVFVSAVFVGIVLA-PWIVLLGLWSSIKPRPSILPFTALLTAFEGLLFTYWLRLRLGQVLALLAIPTVFAGKHALASASAWRQ Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 ALLAASSLARAAIVVKLSLIDAVGTTAFTPLPARQLSPTDALKLSFTVNDSAPFAPQQAAV-LVQPVNVKVRQNSGKARWDLDLSRADPSLLSLPLSFTLILGLGTFTLPSSRYKPMPEIQWTFR--EGEKKVNKVLALGGTAVVLA-PWLVLLVAFRYILPSPLILTFLASLTALELLFIVYWVRLRLIPTLLGLGAWNAWIGRRALGEVRRRRI Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 LGLAAA---AAQLTLRFTVTSEAGSEPISSMGLVTLSPTDTLKVAFQVETGEGVQPHQVFLRFYDPETIRV-SAGGKAKFELNMAKPPPSLPPTPLAVSLIIGIFDLVVPPSRFHLLPEIQHTFR--PDQKMPPKFISFVASLITLS-PWVVLIGLWSLVNPRPSILPFTVTLGAFESLLIWYWVDLKLGQVLAGLAVVTLFAGKHALVTISEGRT Schpo1 LLFAR----CASWNVTLQLSSQDLAYDLKQSSTVELTGDETLNLKFTC-NGTGAIPHQAHLLLSDTEHASV-SQGGVASLELRLFDIPTSLLRSTLTAKLLVALGQLSINVPEFSPLDEILHTFS--PPPKRANYFLSICFSVSVVV-SLIGLLGVWQKLLPKVSSSSFFASLAVAEILLFIYWTSLSIFQFGAGVAIMCGIAAKSL--------- Sorma LLLAAVQ-AASSWSFSVSVAAKKGKEKFSLTKPVGLGSTDTVKIILTAGKAK--RPHQAFVTIKEQETLTV-KDTGKAVVSISQKDLPVQFLLSPLKASVVIGVFDIELETDRYGKKPEIHHIFR--ADPQSPPKVISLFFALVVAA-TVPALFISWLLLGANLSHVTFFGSIVAMEGVFFMYYTSWNLFHVLGVVGIVTVLSGTKALGEVQSRRL Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 VLLALHVYARRVIPSTLKITGADGSETLTISKPLTLGSGSKLTLNVPVDKGKALSLQHLFLGARNDKTCAS-KGTGVFTCELDQS----TLDKLPHTLTLYAGLGTAEFSIAVFQPLPEITHKFR--PADKMPNKILSLTFSGLVLA-PWLLLLGSYIVLGANISGSAFMGSLSLCVLLYYVYWVKLNLFQLLSLLGLITAILGRQALVARAAMRS Sporo1 -----------------------------------------------------------------------------------------------------------------------------------------------MVLA-PWVVLISIFSYLSRSVLIL----SLISFELLFVTYWVKLRLIPTLAVLSGIAVLSGKRALGEMRRVRI Stehi1 PLLASAQ--AAQLALSYQVLSSDGSEQITQAKFVVLNSTETLKLSFQVGTEKGVQPHQAFLRFYDKSTVKV-GPTGKAKFELNMAKPPPSLPPSPLSVTLILGLFDVQIPPSSFYLLPEIKHTFR--PEQTVPPTVVSGFFTLLVLA-PWVVLIGLWTAVSPKLSIFPFTGTLVVIEALLFWYWTSLRLGQILSAAGAVAVVTGKWALASMGERRL Tapde11 ALLGV---RASSWTFKLDISGTPY-----SSEPISLWPEEKLKLLLTIDDAK--KPHQAMLLVKDSESIPV-KSTGRGSLTVAYKDLG-PLLTQSIDLTLVLGIATISLEETRYGALPEITHTFR--EAEKMPPKTISIFFSLVLLT-GLAGLAGAWLTLGVNITYTVFLGSLFALEGSLFLYWTQWRIMTALVTLSVPAYFSGRSALRETESRRL Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 LALSAID-ARSGLGVKVVISSPDGTYSLKLPSPIALTETSSFKLTFTVT-GSSVFPKQAHLLFEGIA-VSV-KPNGRASFTLNTSKPPSALLPTNFSLTLLLSIGHISIPPAAFRAQQELFHTFQ--PEEKTVSWIWSVLGTGVTLS-PWVVLLGLIRPATKETSVWPFLLCLTAIEVLTATYWVGLKIYQLLLGTSLLAGYTGKVALGSLRQRRL Trire2 VLALAAS-AASSWTFTVQVTSKAGA-KFSVQNILTLGHQDKLKVTLTTSQAK--RPHQAFLVVKEA-SLTV-KESGKGTVEITQKDLPVQLLLSPLEASLVLGVFDLAVKLDRYGKLAEIHHIFR--ADPKNPPKMVSIAFSLAVLA-TIPALFIGWFAIGGNISHVVFFGSIVAMEGVFFLYYTKWNLFQTLGVVGVAAFLSGTKALGEVQRRRL Umbra1 FTLASAAGVEDE-----------------------------------------------------------------------------------------------------FGVQPEIVHQFR--AQEKMPPKIVSQLASLLVLA-PWIALLAGWAQLGYTVSIFSFLGTLAAIEFLFFNYWTHLNLFQTLSVLSVVAFITGQRALTVVQQKRI Ustma22 LFLSVAALSEPKLSYKLALSAVDGSKDFSLSSP-QLENDDVIRLTLNLALGKEHVPHQAFVVLASEQDVVVKPSTGRVSWNLRMDRIPASLLRA---LSLLIALASLTPPPSGFHGLPEHKHTFGVSPTETMPSTKISGLASLVTAGVPWLFLLAA---LG--SKALVLFAALVGLEGLAVRYWIGLTLFQMLLGGGLVTAVVGRSTLGELRKKRL Walse1 GLLASAKLELSGSRIGLNIDQSKF----------ELENDANVQYTFYTSEGISITPDRASISFIDKSSVGIRQSDGRGRFSLRTAQFP---LKSGLDIKLFVAVGRLTFSKESFVPLPEIAHTFK--AEVEHTPAVVSGVATIIINGIPWLLFAILLSLLKFDTTNSAFICTLLAFEGLLIKYWVSLTLFQFIIVNGLAVFLSGNKALKVLKRRRT Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3877.fasta_al_trimmed; alignment length = 132] Allma1 LDQQIAKMRAAWEHF--N-LGKASPTMLDKVVVALPQVAQVSLKTLLVIVPDENFTKAVETAIRSS-GL-NLNPSLKVPVPKPTAELRQSLAKQVHKVAEDTKTKVRTVRQHEISQKFEKAVHTEQIDALAK Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------ Aurde31 MQGTVEHHRRELAALEMRGSGRVTPAILDAVRVQLQDVATVGVRTLLVSVYDESSLKHVEKAIYAA-KIPHVVPTLKIPMPKPTVEARKALAVQGAKLTEDLRVQLRRTREAGEKDEFHKLMTKAEIDKNLE Batde5 MQNAVEKLRKDLGLI--R-MGRANPALLDSVRVKLVDVAQITVKTLVIVVSDEQLVSVVEKAVRDA-NL-GLNPSLKVPVPRMAKEFRETIIKNIGRIAEACRVRIRSARADARTKDIQQLTDKKDTDAAVL Botbo1 MKGAVEWFRKEVAMLESRGSGRVTPAYLDPVRVVLQEIATIGVKTLVVTVFEESMLKEVERALHGA-NIPGVHPTLRIPVPKPTVEARTALLSSATKLAEDTRIKVRGAREGGMKVDLQALTDKAEIDKIVQ Botci1 ------------MSL--R------------------------------------HIKPILSTIQSS-TL-SLQPALNIPIPPPTKESRDAALQAASKAGEIASNGVRNARGAMQKKEMEKVVEKGEVKKIVE Caeel ------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------ Capow LSTTAKFLTTALAKL--R-TGRATPAMLDSVKVRLNEHGMVSVKTLVISVNDETVLDDIERAIREA-DL-NINPFVKCVIPKMTQEFREKLTKMAREQGEEYKIRLRRVRAKAITKDVGKAFDDKQIDTTVS Catan2 MANAVEHLKKDFAHI--N-VGKASPALLDRVLVKLDVVAQITIKTLMAIVPEQDNLKHVESAIRAA-NL-NLNPTLKIPIPKPSQDTRAAAAKRVQQSAEQHKALIRNARHDELVVEVEKVTKTDQCDALAK Cioin ------------------------------------------------------------------------------------------------------------------------------------ CocheC53 ------------------------------------------------------------------------------------------------------------------------------------ Coere1 MQTRVDRFASELQAT--R-VGRANPAILDHVRIKLPELALVTVKNLLVIPNDPEERSVIENAIRNA-GL-GLNPAVVVPVPKSTKESRERLIKGLGLSAEQARVHVRKVRQDAMKKDVQVVTDKDRIEQLLK Conco1 ADRIKQKFGQELNSL--R-VGKASPNLLDNLQINLNQVGQVSVKTLLISVFDPKLVTAVERAIQAA-DL-NLNPKVRVPIPKLTKETRQETIKLGQKFLELTKTNIRNVRQLGMKNEFDVDIKKKQVEDLFN Conpu1 MNSTVEWFRRETATLETRAIGRVTPALLAPVRVRLESVATVGVRTLVITAFEEESMKAIEQALYDA-KLPSIVPTIRIPIPKPTVESRNALYTSAARLAEDGRGQIRKHQQTSVKEEFQKLAKGAEVDAILA Copci MKNAVDWFKKECAGYETRASGRITPAILSPVRVKLEELATVGVRTLLITLFDEHNMKHIESALHTC-GIPGVVPTIKVPIPKPTVESRLSLYAAAKKKAEEIRVQVRRQHSTSLKEEFQKLTDRGEVDKILK Croqu1 MGTGVGRLRMEIKTLVNR-VGRLTPAYLDGVKVEIDNIAQVIVLTLSVVPYDASHQKPIEKALYDSPEL-KLAPSILLAVPKMTVESRQTLAKKAGQVCEQARGVIRQARQVAQKKVLDDITKVKQIDEIET CryneH991 MEKSVHWAKAVLFEGVERGRGRVSPALLDSVRVTLNALASVTTKALFVEVWDTASLKQVESAIHAA-NLPGISPTLKIPIARPTVEQRAEILRQLAETVEAAKTQIRVARTDGFKDEVQRVVDEKDLDGQLA Crypa2 ------------------------------------------------------------------------------------------------------------------------------------ Debha1 ------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------ Dicdi GDKTIEYVSRELGNI--R-FGRVGPELLERINVELPHMAMITIKTLNITLYDSSLLSNVERALTNS-GL-GLNPTIRVSLPKPTQDLRQKLIKQVNTISEDAKVSIRRHRKDGMDKNIQKITDDKSITKITE Dmel ------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------ Falba ISRTIEVFRTDLAQM--R-MGVANPAILESVTVDLRNLCQVSVLTLQLNVFDASMSEPIAEAIRGG-GM-GLNPIIKVPVPRVTKEYRESLVKQIEKDSEHSKISIRNIRQAALRKDIQKVIDDKEIDSMAT Fomme1 MKSAIDWFRREVASKEIQGSGRVTPDILKPVRVSLTELATVGVRTLIVTVFAEDTLKHVEKAIYAA-RIPHVVPTIKIPMPKPTVEARAELVKSATKLAEDTRVQLRRVEQTSVKDEFHELLQRKEADSILA Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------ Galma1 MQTSVDWFRKECAASEARALGRVTPALLSPVRVKLDELATVGVRTLLITLFDEHTVKHVEAALYDS-GIPGVVPTIKVPIPKPTIEARKELFAAAKRKAEDIRVQVRKQHAASLKEEFQKLTDKREVDKITA Ganpr1 SATVLDRLTADLATL--R-LGRANPAVLHNVTIPLTQIADVKLKTLLVLPHDEELLSAIAKAIRAS-QL-GLNPALKVPIPRLTQDARDQLTKQCKDYGEKAKSAARAVRHDAREKAIDDLANKKDVDAVVK Gloin1 ANIVTEKLKKDYSSM--R-IGRANPAILDPVSVPLKDIAQIIVKTLLVHVHEEELLKAVDKAIRSA-NL-NLNSSIKVPIPKITTEYREKMTKVASKIAESAKIKIRRIREDGMKKKLQSLIEKKDVDEILK Hisca1 ------------------------------------------------------------------------------------------------------------------------------------ Klula1 ------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 MKTAAEWFRKECASSEVRASGRVTPALLSPVRVKLEELATVGVRTLLITLFDEHTIKHVESALHTC-KIPGVVPTIKIPIPKPTVDARHALYAAAKRKAEEMRVQIRKQHSLSVKEEFQKLTDRGEVDKVLA Lenti61 MQGVLDWFRKEVAALETRATGRVTPMLLSPVRVKLEEIATVGVKTLIVTVFEEHTLKYVEQAIYEA-KLPGITPTIKIPIPKPTVETRNALYTTASRQAEDVRVQMRKLHQALLKATYQALSDKGELDKILA Malgl1 MESVVARCSEHVRTLVGS-LGRVDAALLDDVRVSLHNFATVGVRVLVITAYEPETLKHIEKAIYAV-GK-DLAPVMIVHVPKPTGETRKILLQKCIKECDHAKTMLRNVRQSAQKKKLEEITKKALLEQVAA Mellp23 MNSGVSKLRVEIKSIVNR-VGRLTPAYLDGLKVEIEGLAQVIVLKLSVVAYDASHTKMIEQALYDS-SL-NLTPSIHLAIPKLTTESRQLLSKKAGQVCEQARSVIRNSRQLAQKKVLDEITKAKLVDEIEN Mnele ------------------------------------------------------------------------------------------------------------------------------------ Monbr YHGQLQHLLNEYATI--R-TGEVTPNLLDGVKVKLSQAGMVSVKTLIVTTFDSDTAKAAYEAVVDA----NIAPVIRIQMPKLTKEYREQVVKRAKEMLEQTKNKMRHLRSHAVSEYLDAINTHAQADEMYE Morel2 MGQCLERLKKDFMTM--R-AGTANPAILDPVSVKLRDLAQVSIKTLMVNVNDVELTGAIEKAIREA-GL-NLNPAVRVPVPKPTKEFRESLTKLAAASTEKAKTIIRKLRQDGMKKKAQTLHDKKDAEEALK Mucci2 YEKLISQLKEHLSVM--R-MGRANPSLLDNVRVRLKDLAQVTVRTLLVTVHDADYMSAVDKSIREA-GL-NLNPVIRVPIPKPTKESRDKMAKLVSTTGEQTKHKVRSLRQDGMKKTVQNLTDKKSIDELLK Mydma ------------------------------------------------------------------------------------------------------------------------------------ Neucr2 ------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------ Phybl2 MSNANSSLKEQLTTI--R-VGRANPAMLDSVRVRLRDLAQVTIRTLVVTVHDTDYLSAVEKSIRES-GL-NLNPILRVPIPKPTKESRDKMAKLVVQAGEQAKAKIRSLRQDGMKKLVQTLTDKKSIDELIK Picst3 ------------------------------------------------------------------------------------------------------------------------------------ Plicr1 MSASFKWFQKECAGLETRATGRVTPALLDPVRVSLNEVATVGVRILTITAFDETTLKSIETGIWDA-KIPNVSPTLIVPVPKPTVDSRVALYNVAHRQAEETRVQIRKHHQASVKEEFQKLNDRADIDKTLA Polpo ------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 MDMTVARLRQNVNLIVNR-VGRLTPAYLDGIKL-INSVAQVIVVTLSVVPYDPSYTKSIEQALYGS-TL-NLAPSLSIAIPRLTIDTRKVLAKESGELCEQARAGIRNIRQAAQKKSLDNVSKTKLVDGIES Punst1 MDAAIQWFRKECATLEGRATGRVTPALLAPIRVKMEEVATVGVKMLVVTLFEEGSYKHVEDAILSA-RLPGITPTIRIPIPKPTVEARAALYTTAATQAEDVRNQIRKHRITAVKEAFQKLADKEEVDKILA Rhior3 YEQCIQSLKEHLSNI--R-VGRAAPSLLDSVKVRLKDLAQVTVRTLMVISHDEDYVSSIDKAIRDA-GL-NLNPGIRVPIPKTTKETRDKMAKLVNTTGEQSKTKIRSIRQDAMKKSVQNMTDKKAIDDLLK Rhoto1 MSEAIDRLRVSLKQIVGR-VDTVKPSLLDNVRVDLNEFAAVSVKELIVNCYEPSFVKLVSDAIYAS-PL-GLAPKLRVPVPKADDDKRHQLVRDAQTLCEKTRQAIRKVRTDGQKKKLDDATKKAEVDRIFE Rozal11 ------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------------------ Schco3 MKAAVEWFRKDCASAEARASGRVTPQLLSPVRVKLEEVATVGVRTLLVTLFDESTMKAVESALYES-KLPNIVPTIKIPIPKPTVEARQRLHTEAQRKAEDTRVQLRKQMQTSVKEEYQKLLDREEVDKTLA Schpo1 ------------------------------------------------------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------------------------------------------------------ Sphar ----------------------------------------------MISCYDPSSAPHVVSAILEA-DM-GLNPMIKVPIPKTTKETRQTLIKKCKEIAERAKVNLRGARGKGMDKRVQKEHDSKELDAIAH Spipu1 MHRGVTRFREDVGSI--R-LGRAVPSLLDSVVVALSAIAQVNVKTLMVIVNDEELVPIVDKAIRNA-DL-GLNPVLRIPIPKLTQAYKDTLLKQAAQLAEKTRNHVRTVRADARAKQIQVVTDKGQVDEALS Sporo1 MKEGIDKLRVNLKTVVGR-VGRVSPALLDNIRVELNEFATVSVKDLLVTCYEEAGVKAVTAALYAS-PL-NLTPSIRVPVPRPDWDKRQGLVRDAQDLCEKARIAIRQTRNDGQKKKLDDATKKAEVDKIFE Stehi1 MSTAVQWFRREVAQMETRASGRVTPQLLAPVRVKLEEVATVGVRTLIVTVFETDTLKDVETALYDA-KIPGVVPTIRIPIPKPTVDARLALYTSASKQSEDIRQQIRAHHSASLKDEFQKLEKKSEIDDILA Tapde11 ------------------------------------------------------------------------------------------------------------------------------------ Thetr MEDAVEGLARRVTGL--S-SGRAAPELLDSVRVDLAHIAQVATKMLSVTLFDPSLTSETEKAIRAA-GL-NLNPGLHVPVPKVTAELRRERLKQLAAWCEDARVAVRAARTDGMKKEFEAVVNGEQIETVRS Treme1 MNKAAEWARGQVWESVERGKGRVTPALLDSVKVTLQEIASITVRALQLEVWDPDLTKSVEAALHKA-NLPGLHPVLKIPVSRPTAEQRTEILRALGTSIETAKQQVRQARQAGLKNAVQKISEDGELDGLLA Trire2 ------------------------------------------------------------------------------------------------------------------------------------ Umbra1 MNQVSDWLKKDLAGI--R-IGRANPALLEGVSVSLHHITQITVKTLLVILHEPDYLSPVEKAIREA-GL-NLNPNLKVPIPKPTKEHRDNMVKIANKAAEQARTRIRSVRQDGMKKQVQKYTDSKEIDDILK Ustma22 MSRAVERFRSTASTLVGS-FGRADPSLLDSIKVELRDFATVGVRALIVTAFDADMVKHIERAIYAS-NL-NLTPVLRVAVPQPTTESRQALVKDLTKICENARVSIRDARHKAQKKKVEAETKKTQVDHLFE Walse1 QKEIVNKTKEDLETLVNR-VGRVTPDLLDSVSVELQSVASVSVKSLIISVFDASMIRDVEKAIFAA-NL-GLTPVLKCLVPRPAADTKSKLAKDAAGIAENARIALRLRRQALQKRTIDKMMDEKSIDDLLH Zygro1 ------------------------------------------------------------------------------------------------------------------------------------ [Cluster3881.fasta_al_trimmed; alignment length = 243] Allma1 ------ADGSTA--YRRRTKPFFRRRKTHTERLHLETNRLQSRLR-KLIEAEQE-LVWERDEDVLSCSQCSTTFSRKHHCRLCGCVVCGCSST-SRIRLCNACLHVL-SARKRSELYEEIKRHVDDTIPLLRETIDVLEALATTYKKDLEAMFAELTQLCQAVSLPTSTPMEAQLHGNLTSDYVQSRM-PALNRAAALEMHHTLIAQLAYFVHEATQARRLDDVRTLSANQDELAQEIVEMEL Ashgo11 RSHYKPKLTPRT-GSVDRTDEFIRHRTSKNEDKQLRILQLENRLV-RLVDLQKS-VTWKENSQASSCYLCSRPFNRKHHCKLCGLIVCECSKE-FRLRVCVVCIRSVFRARLQFSKYTELSRAILRIMPRFEQLLGDLNDELAHLRRKLLETFKLYDTIAKQIFIDPANTAELKIQQAISMSFIQDKM-LPLKNIPLYREQLVLKEQVEGMLENAKKQRRFEEVNTLKENTKELDNQILEETL Aspfu1 KDHWQVRLNATN-GVRDRMDEFKAVRKQTVDKATLEISRLEKRLT-RLTQLEQT-IVWQDDAGVPRCPFCQQEFTRRHHCRTCGRVVCGCSNE-VDIRLCKECKSTLFRRDFQVRAYENLERGIRQLLPKFQKLLATLQAEASKVRKRLTDSFAQYDVAARRIRMPTDSPTQQRLQKAIATNFLHLHM-LPLKALPALRERLVLEEQVSEMIADANRRRKFDEVSSLAMNIEDLSREIINGML Aurde31 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 RIHWQLTLGILS-GSRNRTQGFLKVRGMRIDRALLEANKIEKRLE-KIT-IDQA-VVWVPDDSSSQCYICGSQFGRRHHCRLCGRLVCGCSTM-IQIRSCSQCKELIGMRDNSVSLYQQIRSLVQETLPKFNSLLVDLRQIALRYRKQLLDYFTELERHAKQIKLPTSSTMTLRLHENVAIQFLQANM-LTLQLMPELDMTSALDEQLEGMLLDATSRRRLEDAVVLNTSLSELRQELVQQKM Botbo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 RTHWQKRLGAVN-GLRDHTNDFMAMRRKHVDKAYLEISRLEKRLT-KLTQLEQS-VVWEEDAKVPKCPFCQQEFGRRHHCRLCGRVVCSCSSE-IDIRMCRDCKTTVFKKDFAQRAYENLQKGIRLLLPNFQRLLVALQAEAAKVRKRLIDSFGKYDQAGRRIRLPTTSPTQQKIQKSISSTFLHLHM-LPLKSLPELREKLVLEEQVEGMVKDAGKRRKFDEVEALKANLQDVQREIVMGCI Caeel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 RSHWKQTLSVKN-G--DLTEQFKQKRLAKVEAQQLHRTRIQRNFI-KLTDMNKS-SVWSPNTK--NCSICFVEFNRRHHCRLCGSVVCDCSMN-VRFRCCIDCKNSLLDWK--LTMYEAMRQQIEKLMPQYEQLVGDND--SSKLRNKLVHVLKELEILVFQFRIRIGYEQYEKVITNIVAVFLQDNL-LKYKQITEMREQLVMNEQVENLIKEYTKARRFDELDSLIANKNELNETILESEL Cangl TSHHEVKLTKSN-GTVSKTSEFSRLRSSKMEDKQLRSLQLETRLL-KLIDYERS-IVWKDDSNVHTCNICTSEFGRKHHCRLCGNIVCDCSYQ-IQVRLCSTCIDNLLKRKFKLSRYETLADVIRTILPPFQDALQKIDADLSKLRVKLLRSFANYNSVNKQLCIKPSNFSEERVKNSLSSYFINENI-LPLRSLPQGREELVLEEQIESLVETAKRQRKFDEVATLATNLNELNQRALREKL Capow RAHWEDEFGFRE-RSRSWTKDFQAIRRKHNGDLELSTNQRLNRLD-KLLSAERA-VVWEDDSKVSVCRTCARSFGRRHHCRLCGFVVCGCS-D-MEVRVCHTCVQLMFRATQAAQIYERLRKQIEELFPRYREKANDVSGEGLQLKAELSSLFDQLDKLSQEIYRERKAVCQMQIQNNIAVAYRAENL-IQLELLSPHQQQQ--QQQQRAAPAASTQMRSFRQASGVNNNALSLQAQVLRREL Catan2 ------AASTVS--TVRKTKLFLRRRKTFTERLHLESNRLQTRLR-KLLDAEQA-IVWEPDTHVLACRQCNSTFSRKHHCRLCGRVVCGCSVK-DLIRLCVACVDTLGATRGAVLAYEQLRREIEDGVPKLKELISKLETLATTYKKDLDTHFASITQICQKLSYNPQSTTESKLKLALHTDLVQSLM-STVNSAADTEEYLTLIEQLEYFLKEATEQRQLETVRTLKVSLDEIVAEVVEVKL Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 RAHWQRTLGGGQ-PERNHFDEFAKIRQKHIDRERMEVSRLEKRLT-KLTQLEQS-IIWEEDAKVSNCPFCQQEFSRRSHCRMCGRVVCSCSTQ-VDVRMCKDCQHTLFRSDFEQRAYENLERGIRLLLPRFHKLLQALQTDATKVRKRLMDGFAQFDVAAKRIRLPTDSPTQRKLQKAVAYSFLSLHM-LPLRSLPELRERLVLEEQVSEMVSDATKHRRFDEVSSLVQNLDDLNGEIINGQL Coere1 RTHWQQSLTPQT-GTRSHMRGFVHMRRKAVSSTMLEGTRLEKRLE-KLALAEQA-VVWEEDVDVANCPFCAKTFGRRHHCRLCGRVVCGCSAL-LDIRACRTCEDVIIHRDLR---------LVEETLPTFNALATRLGPRAARIRRQLTAAFNGMDHASKCIALPVKDATSTRLHSAIVSQYLQLHM-FPLTMLPEKMSSLVLRDQVLGYISEAQKDRRLEDAMSLQASLGDLDVELIERSL Conco1 QTHWEKSLGLLN-GTRSWTEKLAKLRKQEVDKVHLEVNRLEKRLE-KLAKTEKM-IVWEDDEKVTNCPYCYKKFGRRHHCRVCGKIVCGCSSK-LEVIVCRDCNDRIYRNEIKAKLYPTLKEVILKTLPMFNELVFNLRQRTVKLRRDLMESFTSFDSINKKIRLAFNSHSQKVINKSIGHMFLQTYM-LSLSLLPEHRNQLVFREQLRLLQQEATKHRKLEDYQSLELSIQELNAEIIKDKL Conpu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 RKHWQRSLGPMA-GMVDHTKTFADIRRKKVERQNLEIQRLEKRLT-KLTQLEQS-VVWEEDAKVPRCPFCQQEF-RRHHCRMCGRVVCACSGE-VDVRMCRDCKTTIFKRDFAQRAYETLERGIKMLMPSFQRALVALQQEASKLRKRLTDSFTKYNLAAKRLRMKTTSPTQLRLQKNIASGFLHTYM-LPMKSVP----------------------------------------------- Debha1 RVHWKKSLNVKN-G--DLTNIFLQKRQLHVDTKELIRNKIQKRFI-KMVNLNNS-K-WQIDATITHCNICLTKFNRKHHCRLCGKIVCDCLIV-VSVRCCINCKNDLLEWKLKFLVYTEIKRKIQVMIPRYKALVTEPD--TNKLRIKLMTFMKDFESLTVLFKVKELYLPYARLINNICTIFLQDTL-VNVKVLNELRESLVMNEQVENLINQVTKQRKFDELTPLMENKNELNAAILELKL Dekbr2 RSHWQKKLGLKN-GEHDLTSSYRKIRSTKSDSSSLSNLNLENRLF-KLVDREKE-LVWNEDSSSNTCSVCHKKFTRRHHCRICGLAVCDCSMA-VSIRMCIKCKRVLFKRLSH-----EIRSEFVLTYTKFRALTGVID-------SKLINYFSQIEQMTKQMESGDDGQSEIRICESLMIGYIQENM-PRLRSIQLKREKLVSMEQIENLHERYKKQRKFDDLQALDDNLKDLNKEIIHQEI Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 RHHWQRSLGPLN-GLTDHTNAFVEIRRKKVERQNLEISRLEKRLT-KLTKIEQS-VVWEEDATVSKCPFCQQEFGRRHHCRICGRVVCGCSSE-VDIRMCRDCKHTIFARDFAQRAYETLERGIQQLLPSFHRVLLNLQQEAAKIRKRLVDSFGKYGTAAKRLRLPTESATQRRLQAAIASGFLHTNM-LPLKSLPELRERLVLEEQVESMIKTAHGSRRFEEVSALSRNVDELDAEILKNKV Galma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 SVVIGGGVGTGS-GTRSLTSLFASLRAPVANRVALETNKIERRVE-KLAKIEKS-ITWQSDHEVIACPFCRTPFTRRHHCRLCGRVVCSCSSD-VRTTACKECTRIVYSRHTALTLLQRAQRRIE------TESWPAFEIVASNARKKVAEEVQKVEVVVKTLSHPYPTPTDRRIADAILVPYIQTRV--------DLHAQLALSVQLRKQEDDARRGRRGEEVEALREARREVEGEVVRGEL Gloin1 KAHWKQSLNIIN-GTRSCTSIFIKYRTKGIERAHLEGNRLEQRLE-KLAKSEQS-IVWQDDASVTNCPLCRTSFGRKHHCRLCGRVICECSSK-IEIRACKECRSAVFRKEYNVMLYQKLRSAIDSTLPKFQDMLIMLKQLAARSRKELLDNFAQFDAISKRINLLTYSESERRLQSNIANQYLQQNM-LPLSVLPQLRQQLAFLEQLEEFIQEATRKRKFDDLKTLKTSLDEIKLEIKRKEL Hisca1 REHWQGRLTVSS-GERDHTAEFAELRRQKVDKAFLEVSRLEKRLT-RLTQLEQS-VVWEDDANVLRCPFCQQDFTRRHHCRTCGRVVCGCSSE-VDIRLCKECKSTIFRRDVALRAYKNLEKGIRLLLPRFQKLLSALQTEASKVRKRLMDSFAQYDIAARRIRLPTQSPTQAKLQKAIATNFLHLHM-LPLKSLPSLRERLVLEEQVTEMIADANRRRKYDEASSLVQNAEDLSKEIINGMI Klula1 TSHWKKKLNARN-GTRNITQAFAKIRKLKNEDGELITLQLENRLL-RLINLERS-IVWKDDQMATQCGICSQPFGRKHHCRLCGQIVCDCSSD-IGVRICSSCLRYVFKRKLQLQQYENLETLVVNLLPRFQKALDSIHQNLAQLRRKLLQNLTLYDKLSKSIVLDTKSTAEKKIQQSIASAFIEEKM-LPLKKIPKYREELVLNEQVENMLNSAAKERRFEEAISLKTNLSEIDQNILESKL Lacbi2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 KRHWVRGLGIRF-GNRSLTTDFMSIRIKSAEKKHLEVNRLEKRIE-KLAQAEQA-IVWEDDSTVPACYICLSIFNRKHHCRLCGRVICDCSTK-THTRACKECIHTAFRREHAVKYYGSLKARIDLALPRFQEMLTTLGQLAARTRKELLDDFALFDAISKKIALPTHSQHQKQLNTNLATQYLQTNM-FPLSVIPSL-AQLVMEDQVESYIEEASRKRKFDDVKSLKMSLEELENEIIRSGQ Mucci2 RDHWQRVVGVANNMTRSKTAFFLKQREKTIDRVYLESNRLEKRLE-KLARGEQS-VTWEDDRTVKACPYCENSFTRKHHCRLCGKVVCGCSKM-IDTRACRDCQRSVFRKLRNIQLYNQLRKNIEKQLPKFHETILMLEIKAAKIRKSLLDNFTLYDTLAKSIKLPVRSA------------YVTTHL-E---------------------IRKRQQQE-----------------EVQQGQ- Mydma KSHWLDVFGLTT-G---------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKQ-L------------------------------------------------LRKDI Neucr2 RHHWQRKLGPFS-GVRDHMAEFKAIRAKRVDRHKLEVQRLEKRLT-KLTRIEQS-VVWEEDGAVTNCPFCKQEFGRRHHCRICGKVVCACSTE-VDIRMCRDCKSTIFHRDFAQRAYETLERGIRMLMPSFQKALLALQQEAAKIRKRLTDAFAKYDLAARRLRMKTDSPTQLRLQQSVASAFLHANL-IPLKSVPEAKERLVLEEQVQEMLKSARAQRRFEEVSALNRNVEELEAEIAKEGV Orpsp11 KSHWEKQLGIRN-GFRDLTNSFMKTRKSNIEKLCLDENLLVLRLE-KLAKLEKS-IVWKEDASSIQCYICKSYFGRRHHCRLCGNLICSCIED-IETKACNQCKRIIFKKLMNVKLYEQIQGIIESTLPKYNDILLKLSQTATKLREKLIKNFHQIDLL------------------------------------------------------------------------------------ Pench1 REHWQTRLNATN-GVRNQTDAFKSIRKQTVDKEFLEISRLEKRLT-RLTQIEQT-IVWQDDASVSRCPFCQQDFSRRHHCRTCGRVVCGCSSE-VDVRLCKECKATLFRRDFKIRAYENLERGIRLHLPRFQKLLAALQADASKVRKRLIDSFAQYDVAARRIRMPTQSPTQQKLQKAIASNFLHLHM-LPLKSLPSLRDRLVLEEQVSEMIADANRRRKFDEVSSLAMNVEDLSREIVSGML Phybl2 REHWQRTLGRNGAGTRNLSKMFLEQRAKTIDRVYLDSNRLEKRLEKKLARGEQT-VAWQDDRTVTKCPLCLQSFTRKHHCRLCGDVVCGCSKM-IDTRACCKCQRAVFRKTKHFPLYHQLREKIEKQLPKFHDTIIMLEQVAAQIRKSLLDNFALYDTLSKSIRLPAPTAPMKRLQTNIANLYLQRNM-LPLQMLPDIRMQIAYKEQVEGFIRDAQKERRIDDVKTLKNSLDELRVEILQAQL Picst3 RTHWKHTLNVKN-G--DLTSQFAKKRQELLDDKQLARVKVQKRFI-KLADIQKT-LIWQSDKEATNCTICFVRFNRRHHCRLCGNIVCDCSIV-VKFRCCVDCKNSLLDWKLLFLIYNAIKHQISQLLPKYAKHIDTTS-YTNRLRIKIMTFLKDFENLTTQFRVIDDFAADSRLITNISIMFLQDNL-IWYKQLNELREQLVMNEQVENMIMESTKARRFEELSSLEQNKRELDMTILETEL Plicr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 RDHWQRTVGRSGAG------------------------------------GEQS-VTWEDDKLVKKCPYCEHVI----------------------------------RKLSNFRLYHQLRRAIENQLPKFHQFILALEIKATQIRKSLLDNFALYDTLVKSIKLPARSPCMKRLQTNISNIYLQQNM-LPLQMLP----QLTFIEQIEGFICDAASEGRTDDVKTLKLSLQELQHEIIRSKL Rhoto1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 --------------TTDHTYLFTSKARKFNERVSLEACRLLKRKE-KLLKIEEN-AVWQPNDEATHCPICFQAFNRRHHCRLCGRVICD------KLRQCKECVATITYMHKTCKIYKELIQFVDGTLPKFNGLLELFSHSANILRKSLSDSFVRIDKLSKQIKIPEDASQRHKLVNSLITLYLQNHM-FTLRMMPDDKEKLIFEFQVQNYLQDAMKSRRLDDVQSLRLSLKEIENEIIKNKN Sacce1 RSHWEKTLNNNI-GVIDLTPEFFKVRNIKREDKNLRLLQLENRFV-RLVDLERT-VTWRDDRSVLFCNICSEPFGRKHHCRLCGMVVCDCSNE-ISIRLCSHCIDMLFGRKFNFAKYDSMSKVIDSLLPIFEDSLNSLKNDLARLRHKLLNSFNLYNTLTRQLLVEPQSHLERQLQNSISAAYINEKI-LPLKSLPELREELVLKEQIESTIQDYKKQRRLEEIVTLNKNLEELHSRIVQSKL Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 KNHWQPLLNFIN-GIRSRFQTFETFRKPLADKRRIEFLRLSKRMK-KLEELEQS-IVWQDDSVVQICPECNNSFTRRRHCRLCGRVIC-CVLE-IPLLICMSCNQNYFNVLYQ-RHIEHLRQAMVNYYRLYEDSLSELLKIVKDRRKKFLELCVKYDGTMKKIAHPSSNDAEEQFKQNVAKRYLQETI-LRLQAIPKKQEELVLEEQVENMIEDAKAKRKFSEVETLLSSLAPLHEEIITEKI Sorma RHHWQKKLGPFS-GVRDHMAAFKAIRAKRVDRHKLEVQRLEKRLT-KLTRIEQS-VVWEEDGAVTNCPFASRSLGRRRRVR--------------DIRMCRDCKSTIFHRDFAQRAYETLERGIRMLMPSFQKALLALQQEAAKIRKRLTDAFAKYDLAAKRLRMKTDSPTQIKLQQSVASSFLHANL-IPLKSVPEAKERLVLEEQVQEMLKSARAQRRFEEVSALNRNVEELEAEIAKEGV Sphar --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 RSHWKRPLGLRA-GSRNRTQTFLRIRKNRIDNLQLEANKLEKRLE-KLSLAEQT-IVWEDDNSVTSCPLCSKTFGRRHHCRLCGRVVCGCSMM-IEIRVCSDCNRVVARREKWVKLYKMIRGLVEETLPKFNNLLMSMAQMANRYRKNLLDYFSELDKLCKTVKLPGSTPSVQRLHHNIVIQYLQSHM-FTLQLMPTIDPELVLEQQVEGFLQDSLKRRRFEDANALKESLQELGREIRKRS- Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 TDHWQVRARVTE-------------------------------------------------------------------------------------------------------QYDLLRKAIDSLLPRYQGLLTSLVEEARRLRKRIVDAFALFEALSRKIALPAETDTQGRLLHVIAITYLQSRV-LSLQTTSALRDELMFTEQLQQQADDARRRRKFDDLASLMRSLDEIDVEVRQNRL Thetr TSHWISEFSTTH-TMRDRSTAFKAARTARARERVVETNKLLRRLE-KLALFEAS-VVWKPEKAATQCGACEAPFSRKIHCRLCGNVFCSCTQNRVEVRTCSSCFQLATRARLEMRYYHAMRKLINNIVPEYESVTAALDARAVHLQKMLTKHFHKLEALGKRVALDTDSPLTAKVQRNISVVFTQELF--------AQRKAL-------------SRKR------------------------ Treme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 RSHWQRRLGPLN-GSVDHTDMFKAVRRKKVERHTLEVTRLEKRLT-KLTRIEQS-VVWEEDDKVPECPFCHQEFRRRHHCRICGRVVCGCSSE-VNIRMCKDCNDTIFARDFAQRAYETLERGIRQLLPSFHRALVALQQEASKIRKRLIDSFTKYGSAARRLRLKADNPTQQRLQLAVASSFLHTNM-LPLKNIPELKERLVLEEQVEEMVKSATGARRFEEVSALSRNLDELNGEILRKRI Umbra1 RDHWQRTLGRGSAGIRSRTALFLMRRMKTIDRVHLESNKLEKRLE-KLAKAEKT-VVWDDDRSVLNCPLCNKTFTRRHHCRLCGRIVCSCSSM-IETRACKDCKRMVFRKIQKLQLYQQLKANIEKMLPRFQDMVMMLEKLAGQVRKSLLDSFAAFDAISKRINLPAHSSSMRRLQANIANHYLQRNM-FPLQMLPDLTAQLAFDEQVAGFVKDAQRQRKFDDVRTLKLSLSELEREILQAEL Ustma22 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 KNHWQRSSKKSN-AFVDKTSSFIGLRETKNEDKRLRLLQLENRLV-RLVNLERT-VTWRNDRGVLDCSVCFKPFGWKHHCRLCGNIVCNCSSE-ISIRLCYKCIRSLYERKFKLSLCESLSKLITDTISHMEKFM--IRTESKKMRTKLLRSVAMYNSLARQVSITPANPTEAKIKRSVSSTFINEKI-LSLKRVPKYREELVLKEQVESMIEEAKKQRKFDEVATLSTNLNELSEQITQGNL [Cluster3884.fasta_al_trimmed; alignment length = 142] Allma1 LFQQMWQAKKEIRAYHGGNITERQFV-STWPMQALTFAPLERRLDVALFRSTFAPSVYAARQMVSHGKVMVNGKKYLLKDGDMYTVAPTAIPRPFQAPMFIPEYLEVNFNTCSGVFVRSPMCEIPSPFPP--EVHGLAHEYY Ashgo11 ---------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 LFQQRWLSKKLLRAYHGDYINEKIFK-RWYPVGSLMWSEVERRMDTVIFRACLTHSVYHAREMVIHGHVKLNGKVTRLAPGDMVTVNPDAILPAFAAPIFVPAYLEVSYATCSVVYVRHPTSEIPTPYDADGEIMRLAWEWY Batde5 VFQQKWIAKRELRGYHVPNIHERQFLNRHFPIQTLAFGELERRPDVVLFRSHFADSIWKARQMVASRCVLVNGERRRLQDGDMVTVIPKAIPKAYMSPMFTPAYLEVDYNTCSTVFLRSPVMEIPSPLPP--TFHQLAFEWY Botbo1 LFQQRWRSKRFVRAYHGDWIGENKFK-RWYPVGSLMFMEVERRLDVFLFRCCFATSAYQARQLVVHGKVTLNGVKALLNPGDMVSVDPAAMLPAFAAPLFVPAYIEPSFATCSAVYVRHPTSEIPSPYDADGEVMRFAWEWY Botci1 ---------------------------------------------------------------------------------------------------------------------------------------------- Caeel ---------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ---------------------------------------------------------------------------------------------------------------------------------------------- Cangl ---------------------------------------------------------------------------------------------------------------------------------------------- Capow ---------------------------------------------------------------------------------------------------------------------------------------------- Catan2 LFQQMWQAKKEARAYHGGNVTERQFY-KTWPMQTLTFSPLERRVDVAVFRACFMPSVYAARQAVSHGKVMVNGQVYLLRDGDMFSILPSAIPRPFQQPMFIPEYLEVNFNTCSGVFVRAPMSEVPSPFPP--EVHGLAHEYY Cioin ---------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ---------------------------------------------------------------------------------------------------------------------------------------------- Coere1 LFQHMWKAKRDTRGYHDANITERQWL-RMFNTASLMYACMERRLDFILFRSHFVSSIWMARQIIVHKKVKLNGKTHRVKDGDVIAVDPESVSQPYQQPMFLPEYLEVNYNTCSTVFLREPLTELPSPYPP--DFHALAYRFY Conco1 VFQQHWKAKKATRSYHDADITERQWK-KIFAVAALTYAELERRVDFILFRSHFAPSVYAARQLILHGKVFLNGEKLRVKDMDLIRVQPEAVPKPYSQPMFLPDYLEVDYKTCSVVFLRQPTTEVPSPFNP--NVHKLAYEYY Conpu1 LFQQRWTAKALVRAYHGDYINEKIFK-RWYPVGSLMLAEVERRIDVFLFRCCFAHSVYEARRLVVHGYVMLNGKKTRLAPGDMITVDPKAIPPAYSAPLFVPAFAEVSFATCSAVYVRHPTSEIPTPYDADGEIVRLAWEWY Copci LFQQRWKSKALVRAYHGDFIPEKIFK-RWYPVGSLMFQEVERRIDVFLFRCCFAHSVYEARRMVIHGDVLLNGRKTRLAPGDMVTVNPDAILPHYASPLFIPAYIEPSFSTCSAIYVRHPTSEIPTPYDADGALIRYAWEWY Croqu1 VFWQRWKSKAVTRGYHGDWIQEKKFK-RHYPLAALMYTEVERRLDVVLFRACFADSIYEARRMVLHNAVKLNGVKTRLHPGDMIIVEPSSILPPYVSPLFVPPYLEVSFRVCSLVYIRHPTCEIPTPWDADGEVMQLAWEWY CryneH991 PFQLRWIAKRLLRGYHGDHIGYTKFA-RWYPVGTMLFADIERRLDVLIFRSCFAQNVWEARRYVVQGHVKLNGQVIMLNPGDVFTVNPSQILPDYASPLFVPAYLLPSYLTCSAVYVRHPTSEIPSPYDAGGELMSLGWEWF Crypa2 ---------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ---------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ---------------------------------------------------------------------------------------------------------------------------------------------- Dicdi IYRKKIKKKKINLKKQQEPFTQRLFR-KFYGNEKVIIQQLEKRVDMVLLRSGFVRSLYEARQIINHKHLLVNGKIYMINVGDIISFKEGSMFKRFQNYATGPNYLEISHSLLLISLIEEPKTAIKYPFTLQPE--------- Dmel ---------------------------------------------------------------------------------------------------------------------------------------------- Enthi ---------------------------------------------------------------------------------------------------------------------------------------------- Falba ---------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 LFQQRWKAKRLTRAYHGDFINEKIFK-RWYPVASLMFEEVERRIDVFIFRCCFAHSVYEARRMVIHGDVLLNGKKTRIAPGDMVSVDPEAILPPFAAPIFIPAYIEVNFATCSAIFVRRPTSEIPSPYEADGEIMRLTWEWY Fusgr1 ---------------------------------------------------------------------------------------------------------------------------------------------- Galma1 LFQQRWRSKAAVRAYHGEYIPEKVFK-RWYPVGSLMFLEVERRLDVFLFRCCFVHSVYEARRLIIHGYVRLNGKKTRLAPGDMVSVDPNAILPQYASPLFVPAYIEVSFKTCTAIYVRHPTSEIPTPYDADGAVVRFAWEWY Ganpr1 TFEQTWLAKRETRGYHGEDISEDKFLRRHFPIATLCFAELERRLDVAIFRCLFARSVGHARGMVVQGHVRVNGEQYVLKDGDVFSVDPAVVPPPYLAALFLPEYLEVDFTTCSAVFLRSPTCELPSPLPA--ESHALAYEWY Gloin1 LFQQKWQAKKDTRAYHGAQLNEQQFR-RLFPVSVLTYASLERRLDFIVFRSCFASSIWAARQIIIHGKVSV----KLAKDGDIISIDPRAVPIPYMQPLFIPEYLEVNFNTCSIVFLRNPISEIPSPFPP--EIHSLAHEYY Hisca1 ---------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ---------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 LFQQRWRSKAAVRAYHGDYIPEKVFK-RWYPVGSLMFSEVERRIDVFIFRCCFAHSIYEARRLVIHGNVLLNGKKTRLAPGDMVSVDPSAILPTYASPLFIPAYIEPSFPTCSAIYVRHPTSEIPTPYDADGALVRYAWEWY Lenti61 LNWRRWTAKALLRGYHGDFINEKIFK-RWYPVGSLMFAEVERRIDVVIFRACLAHSVYDARRMVIHGSVLLNGKKTRLAPGDMVSVDPKAIPPPYASPLFVPAYLEPSFSTCSVIYLRHPTSEIPTPWDADGEVVRLAWEWY Malgl1 MYQQRWRSKRMLRGYHGDWIPERRFK-RWFPVKSLFMRDVERRIDTAVFRCCFAHSVYYARSLVLHGKVSLNGNVYLLQPGDLLSVEPSCVLPPFAAPLFVPPYLDVSFRTCSAIYLRHPTTDIPSPYPAGGDMFGLAWELY Mellp23 VYWQRCKSRAVTRAYHGDWIQEKKFK-RHYPLAAMMYTEVERRLDVVLFRSCFADSVYEARRMVLHNAVKLNGVRTRLHPGDMITVHPASILPAYASPLFIPPYLEVSFRVCSMVYLRHPTSEIPTPWNADGEVMRLAWEWY Mnele ---------------------------------------------------------------------------------------------------------------------------------------------- Monbr ---------------------------------------------------------------------------------------------------------------------------------------------- Morel2 LYQQKWASKKDTRSYHGDQITERQWQ-SMFPVFSLTFAEMERRLDFIVFRSNFAPSIYAARQLVGHGKVTVNGKPHRVTDGDIIQVEPTSVPKPFSQPLFVPDYLEVNYNTCSTCFLRSPITEIPSPFPP--QMHALAYEFY Mucci2 LFQQKWVAKRETRAYHGDEVTERQFKNKFFPVAVLSFAELERRLDFVVFRSNFCPSIYAARQLCVHGKVLVNGKKHKVKDGDVISVDPQAIPKPFSQPLFVPEYLEVNYNTCQTVFLRSPITEIPSPFPP--EFHSLAYEYY Mydma ---------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 ---------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ---------------------------------------------------------------------------------------------------------------------------------------------- Pench1 ---------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 LFQQKWLAKRETRAYHGDEVTERQFKSKFFPVAVLTFAELERRLDFVVFRSNFCPSVYAARQLCVHGKVKVNGKKHKLKDGDVITVDPHAIPKPFSQPLFVPEYLEVNYNTCQTVFLRSPISEIPSPFPP--EMHSLAYEYY Picst3 ---------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 LFKQRWKSKALVRAYHGDFIGETVFK-RWYPVGSLMFSEVERRMDIFLFRCCFVHSVYEARRLIIHGKVLLNGKKTRLAPGDMVSVDPEAILPPYSSPLFIPAYIEVSFATCSAIYLRHPTSEIPTPYDADGEVIRLAWEWY Polpo ---------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 VYWQKWRSKAVTRAYHGDWIQEKKFK-RHYPLAALMYQELERRLDVAIFRSCFADSVYEARRIVIHGAVKLNGVKTRLHPGDMFTVDPMAILPTYASPLFIPPYLEVSFRLCSSVYLRHPTCEIPTPWDADGEVMKLAWEWY Punst1 LFKQRWVSKALVRAYHGDFINEKIFK-RYYPVASLMFSDVERRVDVFIFRACLAHSVYEARRMVIHGDVKLNGKKTRIAPGDMVTVNPAAILPPYASPIFVPAYIEVSFLACSAIYVRHPTSEIPTPYDADGAVVRLAWEWY Rhior3 LFQQKWVSKRETRAYHGDEVTERQFKNKFFPVASLLYANLERRLDFVVFRSNFCSSVYAARQLCVHGKVLVNGKKHKLKDGDVVTVDPQAIPKPFSQPLFVPEYLEVNYNTCQTVFLREPITEIPSPFPP--EYHALAYEYY Rhoto1 MFAQKWKAKKLARAYHGDWIPETKFK-RHFPLASLMFSEIEKRLDTVIFRSCLAQSVYGARHLVLAGKVRVNGEKYRMQPGDLISVDPQHILPDYAAPLFVPPYLEVSWTTCSIVYLRHPTSEIPTPYEADGEVMRLTWEYY Rozal11 -----------------------------------ALEDLECRLDNIIYRSMLAHSVYEARRLCSFYSVVVNGKKYRVNEGDVI--------KTYGSPAFIPPNLEVNFRNMSIFVVYKPKDELPQPYDR--QVIESAINYY Sacce1 ---------------------------------------------------------------------------------------------------------------------------------------------- Salro ---------------------------------------------------------------------------------------------------------------------------------------------- Schco3 LFQQRWVSKRCARAYHGDHIKETIFK-RWYPVTSLMFADVERRIDVLIFRSCLAPSVYEARRLVVHGKVKLNGKQTRLAPGDMVTVDPAHILPPYAAPLFVPAYLETSFAACSFIYVRHPTSEIPTPYAADGDVMRFTWEWY Schpo1 LYQKKWNAKKETRSYHGPQLREYQLK-NAFPFMNQTYAFLESRLDMSIHRALFASSALQARQLVLHGKVHVNGKPRQLLPGDLVTVDQKSVPKPFMSLAFIPAYLEVCFRTCSFVYVRDPVTEVPSPFPE--DLHALAYTYY Sorma DFGTQLRAKQKLKGYYGD-VTEKQFK-RTYDTGQNLIGLLEQRLDMIVYRAKFAPTVWAARQLVSHGHVRVNGVKRRCYVGDEISLGTKAQ---------IPEYIGAD--GTKVTFNRVPTDEVPYPG-------------- Sphar ---------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 VFQQKWTAKRELRAYHVPNITERQLIQRHWPVQALAFAETERRLDVVVFRSHFASSIWQARSFVIQGHVKVNGKPRSLEDGDMVTVDYNVVRVDYMAPMFLPAYLEVDYQTCSTVFLRTPLVEVPSPFPP--DWHQLVYEWY Sporo1 MFQQKWKAKQLVRGYHGDWIPEQKFK-KGYPLASMMFAEVEKRLDTVVFRCCFADSVYKARQLVIHGKVKLNGQKIKLQPGDLISVEPEAVLPDFAAPLFIPPYLEPSFTTCSAVYLRHPTSEVPSPYEADGEVMRLAWVSI Stehi1 LYQQRWLSKKLVRAYHGDYIPEKIFK-RWYPVGSLMFMEVERRIDVVVFRCCFAHSIYEARRLVIHGRVLLNGKVTRLAPGDMITVDPKAVLPPYASPIFIPAYIEPSFKTCSAIYLRHPTSEIPTPYHADGEIVRLAWEWY Tapde11 MYQQKWEAKKETRAYHGDHLVERQFK-NLWPLASQTYASLEKRLDIAIFRALFASSTKQAKQMVVHGKVSVNGREHILKAGDLFEIDPAAVPKPYMSAAFIPSYLEVSFETCSAVYLRDPVTEVPSPHVA--GVHALAANFY Thetr ---------------------------------------------------------------------------------------------------------------------------------------------- Treme1 LFQRRWLAKRLTRGYHGDQITQTRFE-RWYPVGSLMFSEVERRLDTLIFRACFASSVYLARHYIIHGKVKLNGVVTLLNPGDLFSVDPKAILPPYASPIFVPAYILPSYLTCSAVYVRHPTSEIPTPFDAGGEIMKLSWEWF Trire2 ---------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 LFQQKWIAKRETRAYHGDEMTEKQFK-RVFPVAVLTFAELERRLDFIVFRSNFAPSIAAARQLVIHGKVNLNGKKHRAKDGDVISVDPNAIPKPFSQPLFVPEYLEVNYKTCSSVFLRAPITEIPSPFPA--ELHALAYEYY Ustma22 MYQQRWRSKRFLRAYHGDWIPEKRFK-RWFPTASLFMRDVERRLDVVVFRSCFARSAYESRSMVVQGKVTLNGVKQLLEPGDLISVQPSAVLPDYAAPLFIPPYLEVSFTTCSTVYVRHPTTDLPSPYPAGGELYAMAWEHY Walse1 LFQQRFLAKKLVRAYHGDYIQENIFR-KWFPVTSLMFTELERRIDHLVFRCCLASSIYEARRFVIQGHVKLNGYRTRLDPGDLVEVNPLIVLPPYAAPLFIPAYIEPSFQTCSFIYLRHPTSEIPSPYSADGDVMKLAWEWY Zygro1 ---------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3887.fasta_al_trimmed; alignment length = 248] Allma1 -----RCAALSSNWL-SSLPSFITLPSTFGNIHLGEPLNFALVVNNDVAHLTSVKVELQTSSAVNQS-TEFRAKHDIKELGMHILVVQV---------------------------------------------------------------------QMG--------------------------------------------------------------------------------------- Ashgo11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ---------------------------------------------------------MQTPSQRGQS-LQKIVRFDLKEEGNHILAVSISYRTFRKLYQF-VAQPCLSVRTKSSELRFALEAQLENVGVVVKQTKLNPK--PLNPRDVLQVAFLVEQE-LGQLSIEWRSAMGDKGFLTTGNLLTR--------------------------------------------------------------- Aurde31 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Batde5 HLLALKVMRLSHPSYAAGLGSLLTLPPAFGNIYLGETFSSYLCVNNEVLNL-TFKAELQTSTQPGQS-AEFVIHHDIKELGIHILVCSVHYKFFRKFYKFQVLNP-LSVKTKVNTLRIFLEAQVQNVSMYLEYMNFEPN--DLGQQDTRQYLYMLTPKGLGKLDISWRTVLGQSGRLQTSQLSRKPFEVFVVEQPIRVEQPFVVKIRITNHVMTNVLLRGNNIELNELDVDLEFFALAGLQKILTVVR Botbo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 HSVSLKVLRLSRPSLSFILSPLLTLPPAFGSAYVGETFSCTLCANNEISNI-TLTAEMKIPSTSQTS-LQKVLHFDLKEEGSHVLAVTVTYRTFRKLYQF-ICKGCLVVRTK---IKYALEAQLENITITLTLVHLATT--KLAPGDIRQVCFLVEEK-FGVLSIGWRGAMGNKGFLSTGNLGTR--------------------------------------------------------------- Caeel -------------------------------------------------------------------------------------------MYFRKFFKFPVSKP-IDVKTKFYSADVYLEAQIENTSMFLEKVELDPS--QLKPKDIRQFLFCLTP-SIGKLDMSWRTSMGEKGRLQTSALQRIDVRLSVEKTPVDVQKPFEVSCRLYNCS-RHLVFCSSGVSLGQLDFSLNVFPVTGIQSIIAQIF Canalb1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow HYLVLKVMRLSKPTLVFSLSSFLMLPQNFGNIFLGETFSSYISVHNDIRDV-AVKAELQTTSQPGAS-VDVVVHHEVKELGVHILVCSVSYKIFRKFFKFNVLHP-LAVKTKVYNVDIFLEAQVQNITMYIEAVKFEAM--PVNPQDIRQYLYRLSPKKIGKMDILWKTNMGEVGRLQTSQLPRKELAVTVVEVPVVLEVPFTVQCRITNYSMTGVLAAGSGQSLGELIIPLEFFPAVGLQRVFMDVL Catan2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin HPLALRVMRLTKPSIIYGTGETLILPHSFGNIFLGETFVSYLSVNNEVLNV-SLMADLQTGSQPGNS-LDEVINHEVKELGTHILVCTVSYKNFRKFFKFQVLKP-LDVKTKFYNIQVYLETQIQNITICMEKVNLDPA--AMKPSEVRQYLYWLKLKVIGKLDIVWKSSLGERGRLQTSQLQRADILVQVNQVPLKVLQPFEISCKVTNYSRTNLLW--SGYTLNKL-ITMSLLPTSGIQSVIHQVL CocheC53 HSVSLKVLRLSRPMLAFILSPVLNLPEAFGSAYVGETFSCTLCANNEISGV-RIQGDMQTPSNPGES-LQRILRFELKEEGNHVLAVTVTYRTFRKLYQF-VAQQLLSVRTKAGEMRYLLEAQLENMGVCLEAVDVSPK--PLSPRDVVQVAFLLTYK-LGQLAIQWRSALGDRGSLSTGWLTAR--------------------------------------------------------------- Coere1 HPLTLKVMRLSKPALAFVLAEALALPRSFGAMFLGETFTAQVCVCNEMRDV-SFKAVVQTATQGGQP-LNLQVSHEIKELGSHVLACSITYRVLQRSFRFQAANP-LVVKTKVNHLDVLLEVQVHNATMALERLRFDPA--PVLSGDVRQYLYRLRPQALGRLDILWRGPFGSVGRLQTSQLLRKLIEIERAWVVVCVETPFTARLRLRNASHPLVIPCGARYVLGKLELVLEFLPLAGVQRFTLDIL Conco1 QLLSLKVMKMSRPTL-LNSPPLLFLPQQFGNVYLGETFSCYLSVNNDVRQM-TLKAEVQTSSQPGHC-APLVIRHEIKELGIHILICSVHYKFFRKFYRFQVLNP-LAVKTKAHSTQVFLEVQISNVSMFLERLRLDSSRWDLPVNSTRQYLYKLTPKQLGKLDIAWRTELGAIGRLQTSQLTRRMIEIRPTSIPIYLEQPFTIEYRVQNKSMGSVLLSGLTKYLGMVDIELECLSLSGPHKVLTEIN Conpu1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 HLLAIKVLRAARPTF-A-SSTSLTLPNSFGLIHLGQTFHGLVSVQHEAENA-VLRVEMHTTANFGKPGLELAVKHEIKELGLHTLVCTVSYRNFRKLYKFQVSNP-LSVKTKVFVPLIYLEVQIMNQTIVFEHVKL-PT--ELYAGDASQFLFSIVHPVLGRLDLAWRGKMGEPGKVQTSALTRK-LLVEDFDRAIQVGKPFKVTYLIRFPSRSNISLEPNGVQPPLIKFCLNYLAFEGLWSLVGYIW CryneH991 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 HSISLKVLRLSRPSLVFLLSPVLNLPPSFGSAYVGETFSCTLCANHEIRDV-RIEAEMKTPSSPGRT-LQRIVHFDLKDEGNHVLGVTVSYRTFRKLYQF-VCKPSLIVRTKAGPLRWVLEAQLENCSMQLERVVLELE--PLHPSEVEQVCFVIEEE-FGTLGIGWRGEMGSRGWLATGKLGTR--------------------------------------------------------------- Debha1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi HLLNLKVMRLSKPNIPLGVTSMLQLQS--GVIYLGEMFCCYISLNNHVRNV-FLKVELQTTSSPGFS-SDFVVQREVKESGVNILVCAVNYKKFRKYFKFQVLNP-LVLKTRIHNLVVFLEACLENATLFIESILFEPI--ELKQGCSRQYLFQITPKPLGRLDITWRSYFGEIGRLKTAAIQRKDIECSLINIPIKLEKPFSVIAKLSNKSMDGIKINS---KLDPIQVEIEMFPLKGMQQIV-DTW Dmel HLVALKVMRLMRPTLVLAAGQVLLLPQSFGSIYLGETFASYICVHNTVECV-TVKADLQSNTSPGGT-IDDVIRYEVKEIGTHILVCEVNYQSLRKFFKFQVLKP-LDVKTKFYNAEIYLEAQIQNVTFCLEKVELDGS--ELQPNNSCQFLYCIKPKNVGKLDIVWRSNLGEKGRLQTSQLQRLTLRLEVLDAKIKIGTIFTFNCRVTNTS-PDSQYTGADFMLNLLEFPLSVCPSKGLVKIVVDVF Enthi -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 HSISLKVLRLSRPSLVFLLSPVVNLPVSFGSAYVGETFSCTLCANNDIRDV-RIEAEMKTPGMSGDT-MQKVVSFDLKEEGNHVLAVTVSYRTFRKLYQF-ICKASLIVRTKVGSLRWVLEAQLENCSVQLEKVVLDTE--PLHPGEVEQVCFVVA---FGSLGIGWRGEMGNRGFLATGKLGTR--------------------------------------------------------------- Galma1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 HPLHLKVMRLSAPAFVLAISGLLSLPTSFGSIYLGETFASYISINNEVQAV-GVKVEMQTSAHPHRS-SEHIVRHEIKELGTHILVCSVHYRTFRKFYKFQVSNP-LSVRTKVNSLRVFLEAQVHNAAMFIERMRFEPG--NLHPTDVRQYLYILHPRTLGKLDIQWRGPMGEVGRLQTSQLSRKTLDVLPGAISVPLERPFRITVRIRNNDMGSVLLRGSTYHVGDVEVQLEYVPVVGLHRVVAEVF Gloin1 HLLSLKVMRQSSPSTSLSENELSSLPSAIENIYLGATFDSYLIVNNDARDI-SIRAELQTEKQPHKA-YEFVIKHEIKELGIHNLVCMVQYRYLKKFYRFQVLNP-FAVKTKVNNMTVFLEVQIQNVAMYLERMNFEPG--ELNPQDIRQYLYMLTPKALGKLEIVWRSNYGETGRLQTSQLIRKEIEFSVTSIPIELEVPFKLGCRIRNRTMGSVLLSGSTNYLGELEFSLEFFPLSGLQKVLTDIF Hisca1 HSVSLKVLRLSRPSLSFILSPNVTLPPAFGSAYVGETFSCSLCANNEVSSV-RIVAEMQTPSQKSQS-LQKIVRFDLKEEGNHVLAVSVSYRTFRKLYQF-IAQPCLSVRTKATELRYALEAQLENVGISLGSTTLNPK--PLKPRDVLQVAFLVEQE-LGQLSIEWRGSMGDRGFLTTGNLMTK--------------------------------------------------------------- Klula1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 HLLSLKVLRAARPTF-APKSSTLTLPDSFGVIYLGQTFHGLLSVQYEVENV-ALKVELHTASHFGQNGLELSVKHEIKELGLHTLVCTVFYRSFRKVYKFQVLNP-LSVKTKVLVPQLYLEVQIQNQSIIFQHVKLNPE--ELSTNDSNQFLFLIISQILGRLEISWNSMMGESGRLMTNPLTRKDLLIESLNESIKVGIPFKVIYLINLSSRSS-TIETRSDQVGMVRVSVEYLALEGLKALTGYVW Mnele HALALRVMRLTKPAIIYPYGEVLTVPQNLGSIYLGETFSSFVNVQNDVRDV-VLKTDLQTSSQPGDN-ISEVITHEVKELGGQLLVCTVSYQMFRKYYKFQVLKP-LDVRTKFFTTEIFLEAQITNTTLHMQKVVLAPS--PISPDDTWQYLYKLSPKSVGKLDIMWLSNFGERGRLQSSQLQRLELVVTVQNMPIASDEQFQVVLRLRNTT-SGLIWVGVGEVL---DLQLDILPIKGVWDIIGQIL Monbr --MYKAACWLHSPTVAFGVSEVLKLPAAVGNVYLGQTLSCLISVHNEVSSI-VTKVELQTGSKPGQA-IDQIVEYQLQDPAVHIMVCILAYKQLRKHFKFEVTQP-LEIVPLCKTLDVMVQVNVQNIALILEYVRMTPT--KLPVSKTRNRIFVLKPQKVGQVMVSWRAMRGGRGYTSIATIQRRDVHLDVLDPPVQVGTLCTLRVRIINFT----------------VTELVVMPLRGSHKLLRDLV Morel2 HLISLKVMRLSHPSLVFGVSELLTMPASFGNIYLGETFTSYICANNEVRDV-ILKAELQTSTLSGKT-NEMIVSHEIKELGIHILVCSIQYKSFRKFYKFQVLNP-LSVKTKVNHSRVLLEAMVQNVSMWMERMRFEVA--DFAPNDVRQYLYVLTPKVLGKMDILWRSQFGETGRLQTSQLTRKEIAVQVVKIPIRLEEIFSIEIVVKNQSMGAILLSGNSRQLGPVRVRLDWFPLTGVQKILTHVF Mucci2 ----------------FGLSQMLKLPSAFGNIYLGENFSTFISINNEVQQV-GVKIELQTSSQTQAT-YDTTVSHEIKELGVHILVCSVHYRHFRKFYKFQVSNP-LAVKTKLNNMRVFLEAQLQNVSMFLERMKFEPS--EIHPQDVRQYLYMLSPRALGKLDIVWRSYMGDLGRLQTSQLTRKDLEVQPFWISIMLEQPFKLGIRIKNHSMGSVLLSGGSRQLGEVDTQIEFFPLTGLQRVICDIF Mydma HLLVLKVMRLTKPSIKMAVGEILSLPQAFGSIYLGETFSCYISILNDCKDI-SVKTDMQTATQPDQS-VDDVISYEVKELGTHILICAVTYLYMRRFYKFQVLKP-LEVKTKFYNGLVFLEAQVQNITMCMEQVTLEPS--QMNPMDTRQYLFKLLPKSIGKLDIVWRTNFGETGRLQTSQLQRMDVKLVLIEAPVSLEKQFQIKCRLENSS-NSMLWCGSGKILGPLDITLLLLAIRGFHSIIFKLL Neucr2 HSVSLKVLRLSRPSLVFILSPIVNLPPSFGSAYVGETFSCTLCANHNIRDV-KIEAEMQTPS-PSTT-LQKILNFGLKEEGTHVLGVTVSYRAFRKMYQF-ICKPSLIVRTKAGPLRWVLEAQLENCSILLEKAQLEVQ--RLQPGESEQLCFIIEEK-FGVMALAWRTEMGNRGSLLTLKLGTK--------------------------------------------------------------- Orpsp11 QPISLRVMRLSKPIFSYTDTEILKLPPNFGMIYLGETFVTYICLNNEVHSV-SVKIELQTSTQVKKN-LEYISQYEIKELGVHILICTVYYRSIKRFYKFQVHNP-IAVKTKVNSLRIFFEAQIQNTSMYLEKVSFEPH--ELLANNVRQYLFMLEQIKLGKLDIQWRTNFGEIGHLQTSTLTRKYLHVKVTSIKICVEEPFQCTIEFTNNSNSSILCKGYMKNV-KVSFTIQFIPIVGLHSLLTDIY Pench1 HMRSLSKVHLARPSLSFILTPLLTLPPSFGSVYVGETFGCTLSANNELTSV-RIVAEMQTPSSIGES-LQKIVRFDLKEEGNHILAVSVSYRTFRKLYQF-VAQPCLSVRTKASELRFALEAQLENVGVVVKQTKLNPK--PLNPRDVLQVAFLVEQE-LGQLSIEWRGAMGDKGFLTTGNLMSR--------------------------------------------------------------- Phybl2 ----------------FGLSQILQLPSSFGNIYLGESFGTFVSVNNEVHQV-GVKIELQTSSQPQTT-YDATVTHEIKELGVHILVCSTHYRHFRKFYKFQVSNP-LAVKTKLNHHRVFLEAQLQNVSMYLERMRFEPS--EIHPQDVRQYLYLLTPRALGKLDIVWRSAMGDTGRLQTSQLTRKDIEIQPFWLTVCLETPFQLGVRIRNYSMGSVLLSGSSRQLGDLETQLEFFPLTGLQRVLCDVF Picst3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo QLLNLKVMRLSKPHIPLGISPMLQLQS--GTIYLGEIFTSYISLNNHVTNV-FLKVELQTSTQPGFN-SDFVVQREVKESGVNILCCAVNYKKFKKFFKFQVMNP-LIIKTKIHHIQIFLEACLENATLFLESILFEPS--ELKESGSRQYLFKITPKSLGKLDITWRSYLGEIGRLKTAYIQRKEVECILTHIPVELEKPFVVTAKLVNKTMDGILVNG---KIGALDIDIEMFPIKGMQQILADVF Pucgr2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 HLLSLKVMRLSRPQFAFGLSQMLKLPSAFGNIYLGETFSTLVSINNEVHQV-TTKIELQTSSQPGAN-SDITVSHEIKELGVHILVCSVQY-------------------------RVFLEAQLQNVSMFLERMKFEPS--EIHPQDVRQYLYMLSPHALGKLDIVWRSAMGDMGRLQTSQLTRKDIEIQPFWVQVVLETPFRLGIRVTNHSMGSVLLSGGSRQLGELETELEFFPLTGLQRVLLDDF Rhoto1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 QPITFKVFRLNKPNIMAPVVPALSISQTFGNIYLGQNLSCLVSLLNGINVS-DMRIELHTTANEKGS-LQKTISYEIKEFGQHMMVCT---RNLRK----KVLNP-MSVKTKVNNISILLEVQLQNLMVVMEKLYLESN---FNPDDIRQYLFHLKPKVLGKLDIQWRSSGGEAGRLQTSALTRKDIQVSLEKLHVCFEKCFVASFSVKNNKMKSLLIQGVKKNISNLSLDYTFLPISGFFSLIADVY Sacce1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro HPLTLRVMQLAKPGFAANVTEALQLPSSQGKVYLGESFSAFINICNDVTNV-SLKVEMQTASQRTQT-LQTTIRHEIRSLGTHALLCAVSYRTFRKSFNFEVNQP-LDVIPHCTTITIVLEVQVKNQMIHFQSIKFTPQ--SVEPKESRSYLYKLTPAAIGKLDVMWRSSMGEFGHLQTSQLERPDLELHATNAPVTVGAPFEVECDVINFR--------------DVDASLNF----DLQQV----- Schco3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ---------------------------------------------------------MQTPS-SYTT-LQKILNFGLKEEGTHVLGVTVSYRAFRKMYQF-ICKPSLIVRTKAGPLRWVLEAQLENCSILLEKVKLEVQ--RLHPGESEQLCFIIEEK-FGVMALAWRTEMGNRGSLLTLKLGTK--------------------------------------------------------------- Sphar -------MRCVSPRL-----------------------RGWLC--------------------DGGS-VDTIVTHEVKEMGKHTLVCQVAYVFFRKSFKFVIKNP-LAVKTKVYNVEVFLEAQVQNLIMLVESVRFDPN--PINPNDIRQYLYRLTPKVVGKLDISWKTSMGEQGRLQTSQLPRKDLTLTATSVPIVIGKPFEVGCELSNLSMSDIVMNGSGQHLGEVTVTLSLFALTGLHPILKDVL Spipu1 HLLSLKVMRLSRPSFVFGLSDLLTVPSSFGNIYLGETFSSYLCVNNEVQDV-GIKAELQTASQPTQS-AEFIIHHEIKELGVHILVCSVHYRFFRKFYKFQVLNP-LAVKTKVNSLRVFLEAQVQNVAMYLEKMRFEAN--ELSPQDTRQYLYMLQPKTLGKLDIMWRTHLGQTGRLQTAQLSRKPYDIAVIATPIHAERPFSVTCRLRNNLMSSVLLMGSERSFGNIDFELNFFPLLGLHKILVDVY Sporo1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr TPLTLQVLRLGKPQFAMGLSPMMALPVSSAEVLLGETLMCFVSFHNSLADV-AIKIELHTKTQAGHS-ANYLVKHEVKELGRHMLRCSASYRVVPAKYKFEVINP-LSVTVRIPHHALFVEAELENATLFIDSVTLVPA--PLKPGCARQFLYRLTPASVGKLDIVWKTGFGEAGRLQTSQLARAGLAIEIDELPVAACSPFVAVLKVTNESDAAIALDGSGTAYGELRIPLHLFATRGMHPLLAVIF Treme1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 HLLALKVMRLSRPSLGFGLGEALVLPSAFGNIYLGETFSTYLCVNNETHEV-KMKAELQTSSQPGQS-NEFTISHEIKELGVHILVCSIQYRSFRKFYKFQVANP-LAVKTKVNNMKVFLEAQVQNVSMMLERMKFEPA--ELNQHDVRQYLYLLTPKTLGKLDIVWRTTMGEMGRLQTSQLTRKDLQVQAFNVPIRAEEPFSIGIRISNHSMGSVLLSGSTRQLGDLETNVEFFPLSGLQKILCDVF Ustma22 HLVSLKVMRTSAPSLAFPISELLVLPNSFGTLYLGETFRTYLCVRNEVREP-SLRVEMQVGASTAQA-LETSLAYDIKDLGPHVLVCTVGYRSFRKFYKFSVDRSPISVRTKVHQ-RVELEVQVQNTALVLNELTLKPA--PLADGDVRQYLFVLTPEALGHLDISWRMALGEAGRLQTSQLVRRDFDVAVCDVSEIVSSPRAVGKRVSSTTLSSLRVRGAAEARGELSIGSTLVPLAALMRLVAETL Walse1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3892.fasta_al_trimmed; alignment length = 133] Allma1 ------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 AVSAEASFPASEIFGLVNGHPTQAL-ITFVGGSLVRNLTATRY-GIEISVSYSFATEPQDLRLTIASTVYAHNGTVSVVEPETSLFDPQIIFLYFFLLACFAGTVYFFYPYF-PQAEE--YNAEWIP-AHHIN Aurde31 DVQATAAFPESNPFHVVNGERNAVT-ISVVAGSVIKNLTALSY-NVPLQVPYTFYSEPGDLQLKLWVRVQAFESVVSVVEPPASLFDLKMLATYIIVAGVLGGLGYAAFNYG-PGAAEPVYSEDWIP-EHHLK Batde5 DIKIDYKFPDN----FPSGKTGKVK-FTLVTTTYTKKVSLSPSMDLSFTYNHVFATDAQKANLQIAFRIIAMNTPVEVIFSD-SLFDLKSIMMYIFSTTLFGLVSYLFYVFFYKDAPSPSLDPEWIS-GHTLQ Botbo1 EIVASAEFAESNPFGVVNGERNQML-VTVFGGSFLRNTTTQAY-NVVLSLPYLFYSEPSDVRLTLWARVIAHDSIVTVVEPEASIFDLKLLSVYIIVAGLLGGGSYLAYSFL-TPVSAPVYQEEWIP-EHHLK Botci1 AVSVFAAFPEAEIFGLVNGHASRAL-LTFVGGSLVRNLTSTRY-DVEISLTYTFTTDPQDLRLNILAQIQAYNETVAVVEAATSIFDPQIIFLYLFLLAVTGGTLYFVYSLF-PQKDQVSYDESWIP-DHHIN Caeel ------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------- CocheC53 AVSV--SFPQSEIFGLVNGHATEAR-LSVVGGSLVRNLTSKRY-SIEITVPYSFTLDPQNLRLELITTIPAYNETVSVVEAPNSFFDPQILFLYLVVLGAFGGTVYFIYTFF-PQADQVAYDESWIP-ASHLQ Coere1 ------------------------------------------------------------------------------------------------------------------------------------- Conco1 ------------------------------------------------------------------------------------------------------------------------------------- Conpu1 EIEVEAVFPESNPFGIVNGERNQIL-LAIIAGSFLRNTTALNY-GLRLQLPYTFHSEPGDIRLNVWLRIMAYDSIVTVVEPEASWFDFKLISTYLIVAGLLGGGAYYAYAYA-PQVSSPVYQEEWIP-AHHLK Copci EITASAAFPEDNAFNIVNGRKNALT-VTVILGSLVKNLTEAKYNGFPLQIPYVFYSDPGEHRLNLWVRVEAYDSVVSVVEPEFSIFDIKLILTYLIVAGILGGAGFLTYSYV-PQASTPVYEEEWIP-AHHLK Croqu1 NVEITASFPLENQFGVFNGQPNKII-LKLVWNEFLRKGNPTPS-KRTLTLPYYFSAEEGNLNLKIWVRTLAYDSTVTITEPPTRWFDPQLILLYIIFASLAAGIGYMAYSYLTTPVSTPTYEADWIPSNHQQR CryneH991 DVLVSASFPETNAFGVVNGEDNNIL-IHLASASYVKNATTLKY-GVPLSAPYHVYSEPQELGLTVTVSITAMNRTVSIVEAPGSWLDFQLIFLYLILGTALTLGGWWAYSYFAPKVQAVVYEEEWIP-EQLLK Crypa2 KIDIATSFPDS-TFGLVNGRPTKAV-VEIMGGMLLRNLSAMSY-DVDITLPFPFVLDPQDVVLNLLAQVEAHSGLASIVEAPTSIFDPQIIFLYVFLTGAFGGTLYFIYALF-PQPEPLSYDESWIP-DHH-R Debha1 ------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------- Fomme1 EISVTASFPEDNPFGIVNGERNRIN-LLIVSGSFVKNTSTLPY-GLRLQLPYQFHSEPGDIRLNLWLRVTAYDSIVTVVEPDFSFFDYQVLSTYLFTAVFLGGLGYLAYTFV-PKISSPVYEEEWIP-EHHLK Fusgr1 KAEIKTTFPETDILGLVNGRPTKAV-IEIVSGSLVRNLTAVQY-NIEVELPFSFAQDPQEVRIELQAEVLVHNGSASIVEAPTSFLDPQIIFLYLFLSAAFAGTLYFVYALF-PQAEPLSYDESWIP-DHHIN Galma1 EVIATAAFPETNAFNVVNGEKNGLT-ITVIAGSLLKNLTSQAY-GIPLQIPYTFYSQPGDHRLNVWLKVEAFDSIVTVVDPELSIFDLKLLSTYVMVAGILGSLVYLAYTFV-PQVSAPVYQEEWIP-EHHLR Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------- Gloin1 TVEISGEFTDN-PFNIINGQKNTVK-LTFVTGQLYRNLTAYKY-SVAAEVNYNFYAEPQELGLNIYVRGVGYNDTVTVVDPEVSIFDLQLVFMYLILIGFFGGMGYLIFSFF-GGTEDNNFDESWLP-EQHLK Hisca1 DVAVSASFPNSEVFGLVNGNPTNAL-LSIIGGSLVRNLTSSRY-NIAISMEYPLVTEPQDLRLHLAATVRAYNGTVSIVEAETSIFDPKVLFLYFFLLSAFVGTVYFFYPYF-PQSEQASYDTEWIP-AHHIH Klula1 ------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 EVVATAAFPETNIFNVVNGEKNTIT-LTVIAGSLIKNLTSLKY-GVPLQLPYTFYSEPGDHRLNIWLKVEAYDSVITVVEPELSIFDLKLLSTYAIVAGLLGSLVYFAFSFF-PQVSAPVYQEEWIP-EHHLR Lenti61 VVLAIAQFPESNAFGIVNGERNTIY-LSIIAGSLVKNLTKMDY-SIPLQLPYAFHSEPGEYRLNIWARVTAYDSVVTVVEPEGSVFDLKLLLTYVIVTGILGGLGYYTYTLA-PQVSAPVYQEEWIP-EHHLK Malgl1 EINVATTFPNN-PFNVKNGEATRVV-FTFLTGAFLRNMTTRVMHDDMLQLPFDVYSEPQKLDVEFRANVLLYRGSVTVEEPPQSLWDWQLLSVYAIVLALLGGVGYWMYAYIAPM-AKTTYDEDWIP-E---- Mellp23 NVEISASFPLENQFGVFNGQPNKMI-LKLVWNEFLRKGNPTPS-KRTLSIPYHFSAEEGNLNLKIWVRSLAYDSTVTITEPPTRWFDPQLILLYVIILSTVGGIGYMVLSYSSNAISTPTYEADWIPPTHSQR Mnele ------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------- Morel2 ---------------IVSGEANNLK-VTFIIGTVIRNLTAYRY-GTTLILPYAIKMESREVGLTLMAPVLVYNSTVNFTEPVQSWIDLQLIFLYVLIAGIFAAIGMFIKAMA-PESMTPELDEDWIP-EHHKK Mucci2 NIEVTAQFPDN-PFGIVNGQRNKVV-LDIVTGQVVRNLTATRY-GKALQIPYNFYSEPGEHGLTVFVRVVGYNGTITVTEPEGSWFDAQLLVLYAVLIAGAAGVAYVVRAFF-VDTERPALDQSWIP-EQHLN Mydma ------------------------------------------------------------------------------------------------------------------------------------- Neucr2 KADIETTFPDADIFGLVNGKVTKAL-IDIVGGALVRNLTATRF-QIEITLPYNFVLDPQDVVVELLAEIQLHNGTASIVEAPTSIFDPQIIFLYLFLTGVFGATLYFVYALF-PQSEPLSFDESWIP-SHHLN Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------- Pench1 AVSAQASFPASEIFGLVNGHPTQAL-IAIVGGSLVRNLTATRY-AIEVTISYSFATEPQDLQMTLSAPILAHNGTVSIVEADTSIFDPQIIFLYFFLLACVSGTGYFFYPYF-PQTEE--YNADWIP-SHHIN Phybl2 NLEITAEFPDN-PFGIVNGQRNKVV-LDLVSGRIIRNLTALRY-ELTINVPYTFYSEPGELGLEVFVRVVGYSGNITVSEPESSWFDPQLLFLYAVLAAGAAGVAYIVRAYF-GGVERPALDQSWIP-EHHLK Picst3 ------------------------------------------------------------------------------------------------------------------------------------- Plicr1 EILVSASFPEDNPFGVVNGEKNKLT-LVVVAGSVIKNTTSLTY-GLSLSVPYTFHSEPGDVRLNVWLRVTAYDSIVKVVEPELSIFDFKLISTYLMVAALLSGLGYFAYTFV-PQVSAPVYQEEWIP-EHHLK Polpo ------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 KLEISAAFPTNNQFGVFNGQPNKIL-LKVVWNEFLRKGAPVPS-KRTLIIPYMFSAEEGNIGLRIWVQSIAYDSTVTIQEPPTRWFDPQLILLYIILASTFGGIGYMVYSYVVPVVSTPTYEEEWIPAGHSVR Punst1 EVVVHAAFPEENVFGVVNGERNKML-LLIAGGSIVKNVSQLTY-GLPLQLPFTFYSEPGDHRLKLWLQVDAYDGIITVVEPEVSWFDIKLILTYIFTTAILGGLGYVAYSFV-PQVSEPVYQEEWIP-EHHLK Rhior3 QVEITAEFPDN-PFGIVNGQRNKVL-LDIISGQIVRNLTATRY-GSPLQIPYHFYSEPGDHGLIVYVRVVGYNGTITVTDPEGSWFDIQLLFLYAVLLAGAAGVAYVIRAFF-GDTERPTLDETWIP-EQHLG Rhoto1 DVEATVKFPDDNPFGVSNGRSDNLLHVRVVRAEYIRDTTNLRL-GLAVLIPYRFHSEIGDVGLRVFVTVTGYDSTVTIIEQPGSWFDPALLFAFLLLSGLLGGIGYLVYSYFAPPVDEQTVDESWVP-DHHLR Rozal11 QITAKGIFPRN-PFGLVSGEKTDML-IGFVRGSFLSNLTFSRV-EALLTVKYTFMPEEQDVRFIATAQITVYDDVIKIVES-TSGFDFQMAFLYLMGCVILG----FTFTYM-PQPQAPTLDTDWLPTELQRK Sacce1 ------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------- Schco3 LVAVSAFWPEENPFGIVNGEKNLLV-INVIAGSVIRNLTTFPY-GVSLKLPYEFFSETGDIRLNVWLRVSAFEDIVQVVEPELSFFDFKLWTTYLIVAGILGTAGYLTYSYA-PPVSTPVYQEEWVP-EHHLK Schpo1 ------------------------------------------------------------------------------------------------------------------------------------- Sorma KADVQTTFPDADIFGLVNGKVTRAL-IDIVGGALVRNLTATRF-QTEITLPYNFVLDPQDVVVELIAEIQLHNGPAAIVEAPTSIFDPQIIFLYLFLTGVFGATLYFVYALF-PQSEPLSFDESWIP-SHHLN Sphar ------------------------------------------------------------------------------------------------------------------------------------- Spipu1 GVSFAHEFPKH-RFGIPTGEEVEIL-ITVISGVLVRNLTAYRY-RTDVTVPFRFIVEPMELNLIVFVRAIGYKGIVTVVEND-SLFDLQSISIYLLGAGFFAGVGYFVYSFF---VAVVKPDMEWIP-EHLVQ Sporo1 DVDVVVKFPEKNPFGVTNGVSNNLLNLRVVHGQYLRQTTNFPL-SVDLLIPYRFHSEIGQVGLRVFVSYLGYEGTVEIVEPASSWFDLEL------------------------------------------- Stehi1 EVLVVASFPESNPFGVVNGERNQMW-LNIAAGEFLKTLSNLTY-GINLRLPYSFHSEPGDLKLNLWVIVPAFDGIVTVVEPELSVFDLKMLSTYATVLALLSGLGYIAYTYV-PQVSAPVYQEEWIP-EHHRK Tapde11 ------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------- Treme1 DVIVSASFLETNPFGVVNGENTGLL-LHLAGASYTRNASTLRY-NIPLSAPFSLYSEPQEVGLTVWITLTALNQTVSVVETQAKWYDPQTLFLYLVLISFLGAGAWLAYTFF-PTVKAVVYEEEWIP-VQQLK Trire2 NADIRTTFPDSDILGLVNGRPTTAL-IEVANGALVRNLTAVQY-SLEISIPYSFALDPQDVRLRLLAQVPAYDGETSIVEAPTSFLDPQIIFLYLVLTAVFGGTLFFVYALF-PQADALSYDESWIP-DHHIN Umbra1 AIDIYGEFPNN-PFGIVNGHKNKLN-VYFISGALVRNLSVYKY-DLTIAIPYQFHSEPQDLGLTVIIRGIAYNGTVTVTDPEHSIFDVQLLFLYAVLAAILAGVGYIIQAFF-GSAAPVKLDESWIP-EQHLK Ustma22 ELNIVTTFPNN-PGSVKNGQANTVV-FSIITGAFLRNMTTTSFKSRPLHLPFDFVPEPQELEVEFSLRIHAYRGKVQVVEPPKNWFDLQLISVYVIGFAVIVGGAYFILSYVFGEIAKPS-QDEWIP-EHHLR Walse1 QIELKSAIINS-ISGIINGQTNNLL-INSISGVFVKDAPSVTNIGKTLPYVYSFPSETGDLKLEVSVVLDAFTGVLKVVEPKQT-LDLEMLSIY----ALLAGIAYFVLTYINPLPIRPVGNDDWLPELAKLK Zygro1 ------------------------------------------------------------------------------------------------------------------------------------- [Cluster3896.fasta_al_trimmed; alignment length = 75] Allma1 -----STVARIPLCARASIIPEGTPIKGINYMQGGQDPVALRDEEYPEWLWT-VGKYLKFRRTEAIKLKNFMKGR Ashgo11 SLRSS-VSCRVYDQQAQSSCPAGTPL-NLLIKKGGKEPLALEDSDYPEWLWKVLDKALRRMNREHIKQQNFLAKM Aspfu1 --------------------------------------------------------------------------- Aurde31 LCRQAKPETSPARIPHESSCPANTVMAGLNYLKDQPPVLALPDEEYPDWLWTITSMRMRMENRKLIKDQNFMSKQ Batde5 -----------------SSCKKGTVLKGINVLKDGQDPVAMDDSEYPAWLWKLLDNYLRTITRAKIRANTLAKQT Botbo1 LRRSSESNATSGTAS--SSCPENTILTGIAYLKNQTPVVALPDAEYPPWLWTLLTKKLRKDNRERIKMSNFMKSQ Botci1 --------------------------------------------------------------------------- Caeel --------------------------------------------------------------------------- Canalb1 LKRVSTTTTSTT--TTTSSCPAGTVL-NLKVFKKGDEPVAKEDSEYPEWLWTMLDIKLSKENNSTIKNNNFLSKL Cangl MLRLL---------EAKSSCLAGTPL-SLNVKKTGKDPVALEDSEYPEWLWTVLDKQIRQSNREKIKQRNFLNQL Capow --------------------------------------------------------------------------- Catan2 LAR--ATSTSFAV-ARSSTLAEGTEIP-INYIKGGKHPVALKDEEYPEWLWT-IANYLKFERTEAIKLKNFIKSR Cioin --------------------------------------------------------------------------- CocheC53 --------------------------------------------------------------------------- Coere1 LSRRGDTTTQPAVEKKSSSVVQGTILKGLNIYKDANDPVAQRDEDYPDWLWTLLD---RMDRSQEIKKSNFMRGR Conco1 ---MLSDKVEVKTYP--SSCAEGTKLKGINYLKTQQDPIAKADTEYPSWLWTLLE---RNANKKRIKGSNFLKQK Conpu1 LRRTAAAQATPKV----SSCPANTVLTGLNYLKGQPPVIALPDEEYPPWLWDIQKAQLKKDRQQRIKDANFMKTQ Copci ARRTSAAAKKPGQAA--SSCPPETVLKGLNYLKGQPPVLALPDDQYPDWLWTVLSVARKKERQQAIKDRNFMSTQ Croqu1 QARTS----QSGTISSGSSVKEGTPLKGLGIIKGLGDPIAKSDDQYPSWLWNLIERELNKENRNKIRNANFLKGN CryneH991 SLRPLSACASPKTKPGRSSCPAGTPLANLSVLKDKPDPVALPDDQYPAWLWTLLEKKLKNLNRQNIKGANYLKST Crypa2 --------------------------------------------------------------------------- Debha1 ISRS-------------SSCKAGTVL-NLKMRKSGDEPVALEDHEYPEWLWDCLDKQITKANTAKINNNNFLAKM Dekbr2 --------------TRRSSCKEGTPI-HLDIYKSAQPLIAKKDEEYPNWLWTLLNKLMKKRNVARCKNNNFMAKM Dicdi --------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------- Falba SLRP-------------RAAYSGGIVPNVRVTQTGGDPPHLPDDQYPAWLWDFESKFLKRQRLETIRGENFLRDK Fomme1 TTLRRKDPDTGKRKS-ESSCPENTIIVGVNYLKGQEPILAKKDEDYPAWLWSLLKMRLRAANKKRIKEQNFLKTQ Fusgr1 --------------------------------------------------------------------------- Galma1 LRRRPSSNASPSSA---SSCLPSTLLKGANYLKGQPPVLALEDSAYPEWLWDTLKMERRVANRQAIKDRNFMQTQ Ganpr1 LSRTATCSHSPSADDTASSVPKGTPLKGLNFFVGKSDPVAMDDSEYPPWVFALADAYLRMQNNRKIVYANAQRGK Gloin1 FLSK-SNLKSQQQIQRTSSVPAGTILKGLNFYKDGADPIALPDDEYPNWLWEILDYHHKEKRKQLIKNNNFDRNK Hisca1 --------------------------------------------------------------------------- Klula1 MLRVT-QVKSEASGQAASSCPAGTPL-NLQIKKSGKEPVALEDSEYPEWLWTVLDKQLRIANRANIKQNNFLAKI Lacbi2 LRRPTAAAKKPSPASIGSACPEDTVLTGLNYLKGQPTVLALPDKDYPKWLWTVLQVKRRAANRQAIKDRNFMLTQ Lenti61 LRRQASSASSPKPKS-ESSCPENMVLQGLAYLKGQQEVVAMADDQYPPWLWTLLKVRLRKANRQRIRDQNFMKTQ Malgl1 --------------------------------------------------------------------------- Mellp23 QLKKP---VSSSSAGQSSSVKAGTPLKGLGIIKGVGDPVAKPDEEYPSWLWSLIERELNRENRNKIRNSNFLKGN Mnele --------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------- Morel2 FTSTADD-SAPKAKRTVSSAPEGTVLKGINYMKDGKDPVALADDAYPEWLWEINDKHHKEARRQAIKAENFIRDK Mucci2 LVRSSAS-TPSTTTQRKSSAPKGTVLKGIQYLKDKQDPVALDDSEYPEWLWDLLDQYHRKQSREAIKAMNFMKDK Mydma --------------------------------------------------------------------------- Neucr2 --------------------------------------------------------------------------- Orpsp11 --------------------------------------------------------------------------- Pench1 --------------------------------------------------------------------------- Phybl2 LARTCES-SAPTTPARTSAAPAGTPLKGLNYLKDRQDPVALEDSEYPDWLWNLLDQFHRKQNRDAIKALNFMKDK Picst3 RSRSS------------SSCKAGTKL-NLKVRKNGDEPVALEDTEYPDWLWDMLDKQLGNENSNKIKANNFLANM Plicr1 LRCACSAPASPKKS--DSSCEPNTVLEGINYLKGQNPVIALPDEEYPPWLWTILDYRMRKENRQRIKDSNFLKTQ Polpo --------------------------------------------------------------------------- Pucgr2 LIRTGTQEKKTSQAKKTSTIPAGSPIKGLAYIKGESDPIAKADDEYPSWLWTLLERELNRENRNNIRKSNFLKAK Punst1 LTRRASYAVKPAKKSAESSCPPGTVLTGLNYLKDQEPVVALADEEYPPWLWTLLKMRLKKERQTKIKDTNFMKTQ Rhior3 FVRS-------------SSAPKGTTLKGIQFLKDGKDPVALDDSEYPDWLWDLLDQYHRKQNREAIKASNFMKDK Rhoto1 TCRT-EK-ASPAAKSS-SSCPAGTVLKGLNYLKDASDPVAMEDSEYPSWVWQL--E-----TRLRAEKKELKRQR Rozal11 --------------------------------------------------------------------------- Sacce1 MLARS---------TVKSSCPAGTSL-NLNIWKSGKDAVALEDKEYPNWLWSVLDKNIRKANRQRIKQNNFLSQL Salro --------------------------------------------------------------------------- Schco3 TRRQAAKAAEPAPAA--SSCPADTVLVGLNYLKGQPPVLAKPDEEYPEWLWTILEAKRRIETKQRIKDENFMSTQ Schpo1 LSRAIATSSAQKVANKTSSVLPGTILKGLCIKAGGVDPVAREDHEYPEWLWSLLDTARSHARKSAIRAANFLTKK Sorma --------------------------------------------------------------------------- Sphar --------------------------------------------------------------------------- Spipu1 ALRL-TSQEPPSTVKPKSSCKEGTVLKGLNILKDGKDPVALADDAYPDWLWSLLDKYLRKLTKEKIKANSIAKRA Sporo1 --------------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------------- Tapde11 --------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------- Treme1 --------------------------------------------------------------------------- Trire2 --------------------------------------------------------------------------- Umbra1 -----------------SSAPQGTVLKGINYMKEGKDPVALDDSEYPEWLWDLLDQYHRKQNRDAIRASNFMKDK Ustma22 --------------------------------------------------------------------------- Walse1 MYRNI------------SSCIAGTPLPGLQILKDDPEKVAREDEAYPDWLWTILEKNINKQHKIDIKAKNFLKST Zygro1 YFRVSFVSTSPVLGQAVSSCPAGTII-NVNTKKSGKDPVALEDNEYPDWLWEVLDKQLRKDNREKIKQNNFLKQI [Cluster3904.fasta_al_trimmed; alignment length = 168] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 I-VVRHYV-YCKDCFAKFRKVM---LTLAFSAGLGAVLLD-LVTAIYVAARIEDALHAYLDAMSARITAIESLLIM-RAAPSRGP--I-LFGTQLTALAVTLIAGVAHGAGFTL----PPRVVRPLQDVGAKEC---SITGLTREFMTRLDRDFPSTVSAVARTCAKV Batde5 I-IVKRAE-FCRSCFHRFRGNLSKSLMVAFSGGPSSALLQ-TMCVCYVIVSLEALVQQMFGTLTSKEDLLHYLTLV-REAKAQGC-AI-LLGDTATSVAINVISNTCKGRGLSLPADIDVHILRPMRDILSKEIGIFSISRLSQDFIVGLEKEFPATVSTVARTAFKI Botbo1 V-VIRHAV-YCKKCFIKFRRGLESTLLIGLSGGLGSVLLD-LVMVGYVPLRIENALQSFIASLTAVASLLRTLLLL-YAARSTGS-SL-LLGTSLTSFSVSLISSIAQGGGFNVREEQDVRLIRPLRELGGKECATYGIGKLTRDFIVGLEKNFPSTVSTVARTCGKL Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow VKTASQTF-YCRSCFKNTRLGV--GSKIFTTAG-----LV-HIEALSATARIEDKFLTMLAGV-AREDLVRVLLIV-HIAKSRGY-RV-AFGDSADRIAQNMISFVAQGRGASLAYDTDAILGRPFRALALKDLALYSISTLTEAFVNALQRDFTGTVSTVQRTSTKL Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin I-VVGTNGTFCKDCFHKFRASMGRNVALAYSGGNNSALLN-LI-LIFVIVKLEEKLEKLFNSITSKQETLYRLLLS-RKAKELGY-DV-FMGETSTRLAINILSNFSLGRGVHLPQDTGVKLLRPMREMSMKEIAVYSVQNLTENFILGLVAGFPSTEMTVFRTSNKL CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Coere1 V-TIRQSL-YCKECFVKFRTGQSRLALVAFSGGATSAMLK-LVVIGHITVGVEEYLKALFSSLTDREAMLDVILIL-QLARETGC-GV-LMGDSGTRIATKTVALTSRGRGFSLPIEVDVSVWRPMRDFVAKEIVFFSIDRLAEAFIAELDQDFSSTVPTVCRTMQKL Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 I-VIRHAV-YCKDCFTKFRKALESTVLVALSGGLGSVLLS-VLGVVYIPRRLEDALRAYLSALTAAQSAVQTLIAL-HAAHARRA-SL-LFGTPLTSVSVSLIAGIAQGDGYAVREELTVRLVRPLRDVTMKECAMYSIYGLTKDFIMGLEKDYPSTVSAIFRTLAKV Copci I-VIRHAV-YCKQCFTRFKKTLEPVLVIGFSGGLGSVLLD-LVAVCYVPLRIEDALQTYLSYLTAKESAIQTLLLL-HVSASRDA-SL-LLGTSLTTLSVNLIAGISQGAGFSVSEESKVRIVRPLRDIGIKECGFWSIVSLTRDFIMGLEQDYPSTVSTIARTCAKV Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 Y-IIRNVT-FCKTCFSRFTKSLHPPALIALSTGCGSTLLDLLLWVCYVGLRAEDHLRNLLTSLSSRPQLLSHILLT-TVAHTLPHISV-LMGETSTRQAERLISGTALGRGWQLPLELGFTWLKPMSDLTAKEAAIYSLEMLTENFIAGLGASHPATVSTINRTGGKL Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi I-NFR-SEQLCWECYKKFKLNIVKVLLVALSGGTCSMLLE-LLKCVHIIIPLEDQLKLQFAQLTSKEDLLLYYLLI-QVAHKLNC-KV-ILGTSSNRLAVQLVASTSKGRGFSVPNETDIKFYQPMRDFLLKEIFIYSINTLCEDFLHCLQDISNQTVHTLLRSVDKL Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba --QFRVQESFCAECFLKFRVAIGSSFAVAYSGGFGSVLLDMLLLVLHICAPLELQLREAFAACSARDDLREQLLLR-RLSRAFGC-NL-FSGDTKTTLASKTLSLCALGRGFMLPVEADFLVTRPLRDVSTKEACIYSLIGLSNAFIARLQQEFPSTVSTVTATALKV Fomme1 I-VIRHAV-YCKNCFAKFRRCLDPYLLVGFSGGLGSVLLD-ITYVCYVPVRLEDLLRAYLSSLTAVQSAISSFILI-HTANHLQC-SL-LLGTSLTSLSVSLITAVAQGSGSQICEEFSVKVVRPLRDIGMKECAAWTIGSLTKKFIVGLEKDYPSTVSTIVRTCAKL Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 V-VIRYAV-YCKSCFTRFRKSLEPSILIGLSGGTSSAMLD-LVGVCYVPIRLEDSLKAYLSSLTAFFSAIQILLLL-HTAASRSA-SL-VLGTSLTSLSVNLISGIAQGAGFAVGEEATVRVIRPLRDVGMKECAIWAIGALTRDFIFGLESDYPATVSTVARTCAKL Ganpr1 V-SARSVH-FCNECFVRFKTNLNTGNAHASSSNDHSNILL-AID--NARSSLDDLHQILTSPPTSLALLRRHLALLSLCAHNSAS-YV--LACTASRISARTLACLAQGRGWSLADDISVRMLRPLKEITDHEIWSYTLPALSRRLIGTLTAGFPSTATTVSKTAER- Gloin1 I-LIRHST-YCKKCFGKFRKNVEKSIMVGFSGGPSSAMLQ-LIVVCHIGLYLQDKLSNLLNNITVKEDFIWYLYLI-DTARKNGC-TL-FLGDCSTRLSIKIISLTSKGRGFSLPLETDVIITRPMKDMLSKEIGIYSIERLTEDFIVGLEKEFPSTVSTIARTGAKL Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 V-VIRHAV-YCKSCFTRFRKSLEPSLLVGLSGGLGSVMLD-LVAVCYVPLRLEDALQAYLSSLTAIHSATQTLLLL-YTAASRRA-SV-LLGTSLTSLSVNLISGIAQGAGFSVAEEAPIRIVRPLRDVGMKECAIWGIGSLTRNFITGLERDYPATVSTIARTCAKL Lenti61 I-VIRHAV-YCKNCFHKFRRTLEPSLLVGLSGGLGSVLLD-LITVCYVPLRIQDALRTYLSSLTAIHTSIQILLLL-HTALQTSS-SL-LLGTSLTSLAVSLISGVAQGAGFNVREETTVRVVRPLRDIGMKECAAWGIGTLTKDFILGLEQDYPSTVSTIVRTCGKL Malgl1 I-SVREAS-YCTPCYEKLRANLDHAYAVACDGSLNSVLVH-TMDVLYVPLTLGHLLRAVGTSVTRAEDIRRILVLH-DTAQSRQC-AL-LFPNDATQTAAYVLDALAKGAGHKLPVEGDVLHLHPLSVYLPHELAFYSMGALSQSLITALQHGVSSTSNTVIGTASKL Mellp23 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Mnele V-VIRQGDPFCGTCFHKFRQGLGKTLLVNVSGNVSSAMLR-LLKIVVVVVPFQL-----FSNISAREDIHRSLILS-TLAGILHS-TI-MMSDTSTDLAARLLSSVAVGRGANLPHETGVTFINCMREFTPKECAYYSVNRLTDTFISGLQATFPSTISTVMKTSAKL Monbr V-LLQKDLPYCRDCCRKSRSELGKNIALAFSGGNRSALLG-IITVIHIVLRLEERVCALFADLTARQDFLRTMLLR-AATQQLDC-HL-MVGDCHDQIAMRILVQTTQGRGGNMTRFSGTAMLRPLRAISARELGYYSFESLIQAFVANLTVDFPSTTAAIYRTSEKI Morel2 I-TVRYAE-YCNPCFSKFRTALRNAVMLAFSGGPSSALIH-LFHVCHIGVAIEDKLKALLGACTAKETVLQHFLLI-QLAKRGQC-TL-ALGDSATRVAIQIIELTSIGRGYSLPHETDCKVIRPLKDCLVKELDTFSIRRLTDDFITGLDKEFPSTVATVCRTAAKL Mucci2 ---------------------MTNE-----------AMVN-LTIVCHISYRLEEQLKQLFTNITAKEDLLWNIMLV-TVARREGC-PI-FMADSATRQAIKMISMTSKGRGYSVALDVDLCIMRPMKDMLSKEIGFYSIDRLTEEFIVSIEREFPSTVSTICRTVMKL Mydma -------------------------IL---------------------C-----QFSQ-----------------------------V-MIGDTASDLSITLLCNILQGNGNAIPFEIDIVIIRPLREFSSKEVALYCIQRQTEQFVNSLQAGFPSTVNTIFRTGDKL Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 I-NIRENYPLCKECFHKFRTNIGQAVLIALSGGNCS------------------------------------------------------------------------------------------------------------------------------------ Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Phybl2 V-LIRHAY-YCKVCFGKYRSIITKSVLLACSGGPSSAMLN-LTVICHLSNRLEDRLKHLFANITSKEDLHWHIMLV-SIARREGC-SI-FMADSSTRQAIKMISMTSKGRGYSIPMDVDLVIMRPMKDMLAKEIALYSIDRLTEEFITTLDRDFPSTVSTVSRTASKL Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 I-VIRHAV-YCKDCFSKFRRCLDPSLLIGYSGGLGSVLSD-LVTVCYVPLRIEDSLQLYLSSLTAIPTSIHTLLLL-HTANTTES-SL-VLGTSLTSLSIALISSISQGGGYVVREEASIKVIRPLRDVGMKECAAWGIGGLTKDFIVGLEKDYPSTVSAIARTCGKL Polpo I-VFRTTDTLCWPCYKKFKNNISKSFAVSLSGGPSSVMLD-LIHAIHIIVPLENQLVEVFEQMTSKEDLLEHFLVY-ETAHKLGL-GI-LNGSSSNRLAIRLLSSTSKGRGNSVPNETSTTVCHPMRDFLLKEIAIYSINTLCENFINTLQDISSQTIHTLLRSVDKL Pucgr2 LSTIRNTT-WCRQCFIKFFQGLKIALVIHFKNDLSSLTLQ-LMEVISIILNLDDAMKPLARTLTSRRSFIESLRLL-DFCKHKPR-NVLVKPTTSTQMAIDTLAGVSLGNGWSLDQQIDVLVCRPLAQIVDAELFQYDIPALITDFVVKLEENYPMTSSVINQTVNKI Punst1 A-VFRHAV-YCKDCFYKFGKALEPYLCIGYSGGMGSVLLD-LVTVCFVPISLEDRLNVFLNSMTARMAMVSTLLLL-YTAHSRGS-SL-LLGNSSTSLSIGLISGIAQGGGFAINAELSVRMVRPLSDISMKECGMYSIGGLTRDFIIGLERDYPSTVSTIARTCGKL Rhior3 -------------------------------------------IVCHISHGLDDSLQALFSSITAKEDLLWHIMLL-TVARREGC-TI-FFGDSATRQAIKMISWTAKGRGYSLPLDIDVGIMRPMKDMLSKEIGLYSIDRLTEGFINRLEREFPSTVSTVCRTTLKL Rhoto1 V-VARGTA-YCDDHFSRFRRGTDGALVVAFSGGCSSTLLD-LVEVVFVALKLEDTHLVSLLSNTSLASLRAALLILSHVRQTSSS-PVLLLGDSGTRSAITTLSGMSLGRGFSIGEESEVLVVRPLVHATLGELEHYTIQGLVEDFILSLETSFPSTVSTVTRTSHKL Rozal11 I-LIRHNE-LCKECFSKYKTIVTKCVLIAFSGGFCSAMVH-LSTMCFV----ED--KAQFCDYNLKDDLYQSVIIV-EKAKEASC-SA-LFGDSATKTAANILANVSDGRGFSLPLDTNLMIVRPMSDHIEKEISLYNTHSLTMNFIRGLDKDFPSTVSTVVRTGLKV Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro T-LRKLD-AYCRECFRKARRDMGQHVMLAYSGGNRSCLLA-LIFVVHIVYALEDR--SVFAALTAKEEMLRILLLV-RIAHLHGT-TV-MLGDCATQLAMHCLTLLTRGRGAAIAHLTGVHFMKAFRLLSAKEVALYSYERLTEHFIAGLEVDFPSTSASVIRIAQKL Schco3 I-VIRHAV-YCRDCFYRSRRILDLSLMIGYSGGLGSVLLD-LVYATYISLRLENALRQYLSSLTAVHSAVQTLLLL-HTAVSRGC-SL-ALGTSLTSLSVSLIASISQGGGFAVREEL-LKIIRPLHEIGMKECAAWGITSLTKDFIVGLEKDYPSTVSTIARTCAKL Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Spipu1 V-DMKRVM-YCKTCFYRFRGNLMRAALVAFSGGASSLLLH-LLLICHVHIPLESRLRRSIHGLTAKEDLLHHFALL-NTARKEGC-NL-ILGDNATRMAIRILALTSKGGGFGLPIEVGLVVARPLRDVLSKEVAVYSIDRMTEEFLVGLQRDFPMTVNTVVRTAAKV Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 I-VIRHAV-YCKNCFAKFRKTLEPHLLVGISGGLGSVLLD-LVRVCYVALRVQDSLQTYLRSLTAIPTSISTLLLC-YTAKSTGS-SL-VLGTSLTSLSIALISSISQGGGFVVPQESEVRVVRPLREIGMKECAAWTVGGLTKDFIVGLEKDFPSTVSTIARTCGKL Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Thetr V-ALRNRV-LCGSCVARTRRTLFRS-----SGLLASVALAFLAQGVFITISAE-RVASMLAAESAREELLHLLALV-AYARRVGA-DL-ICGTSATALAVDAFMMLVNGRGEQVPDAVNLWLLRPLLSNLHVEMRGVTLRQLTATFMAGLQDEFPATLNAIAKTVRKL Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 V-ILRHSP-FCQPCFGKYRTVINRSVLLAVSGGHSSAMLE-LTSVCHICEKLEDKLKALFQHISAREDIYWHLMLY-RRAQKEKC-DI-FLGESSTRQAIKMISMTSKGRGYSAALDVNMAIIRPMKDMLAKEIAVYSIERLTEEFITGLDRDFPSTVSTVSRTASKL Ustma22 T-ILRDSI-YCQACAQKAKAGLEYAIAIAFSGGISSALLR-SAYVFYIGLKLHDALKDLFSSLTRIEDLHRIFLLR-RTAKQYDC-AL-LLGDTATRISIRLIEDLAKGAGHKIPVQGDLLIVRPLKTHLLQEVVFYSIARLTETFILNLEKGVPSTVTTIGKTGSKL Walse1 I-QVRHAL-YCRNCFGKFLKWFLATFYIGVSGGPSSYLLH--VVVIYVEVDVDS--DLFDSTLSSLESHLSLLLIL-REAR-----KL-FLATSATRVTIKLLSSMSRGRGWSL----GMRIYQPLLNTSSKEIAYFSIDRLTEELVVSLERGFPSTVSTVAKTGNKI Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3906.fasta_al_trimmed; alignment length = 50] Allma1 -------------------------------------------------- Ashgo11 KYRCPRCSRRTCSLACSRQHKNCSGTSQTTEYIPRGVLKVQRDYNFLIGL Aspfu1 -------------------------------------------------- Aurde31 -------------------------------------------------- Batde5 KYTCPKCRVKTCSLPCVQSHKSCDGKRDKAGYIAKKKYDLTSDYCFLEDV Botbo1 -------------------------------------------------- Botci1 -------------------------------------------------- Caeel KYKCPRCEMRTCSLDCSKKHKNCDGVR--QAFTKVDKLSSIDDQKFMHLM Canalb1 KYTCPACEIKTCSLSCYNKHKDCTGKVDSNKYLNRNELALNRDYNFLNNV Cangl KYKCPRCFKKTCSLACSKQHKSCSGKSDPTAYIPRTDIKVQRDYNYLINM Capow SYRCPACARATCSVACVRKHKDCDGVRVRSSFVELSNMTMAEDVRLLEDA Catan2 KYRCPGCSTLTCSLRCVQSHKNCSGQRNKTAYVPLERYTLYSDYSLLEDT Cioin KYKCPKCSIRTCSVECVKHHKECDGIRCKTEYVAKENFTLLSDYKFLEEV CocheC53 -------------------------------------------------- Coere1 KYKCPGCMVRTCSLTCSKDHKGCSG---------------QRD------- Conco1 KYKCPSCQFKSCSLNCSKLHKNCTGERDPTKFVKKKQYTLTEDFNYLESL Conpu1 -------------------------------------------------- Copci -------------------------------------------------- Croqu1 IYTCPACSIRTCSLACSNQHKPCAGKRNRVEAIPMNKYSLMQDYTYLEDV CryneH991 -------------------------------------------------- Crypa2 -------------------------------------------------- Debha1 KYTCPACGVKTCSINCVKRHKECSGLVDQSKFVPKKILSINRDYNFLMNV Dekbr2 KYMCPSCGTRTCSLNCFKRHKNCTGKSNKTRYAPKGQITVQRDYNFLMKM Dicdi KYKCPGCSILFCSLICSNKHKKCTGVRKDNHFIPLNKFKIVNDFNFLDKI Dmel CYACPKCEVKTCSLPCVQIHKNCDGQRDRTKFVPLSEMTFMSDYCFLEEC Enthi KYQCPKCNILYCSIECYKAHKNCKKKESP--FIPLQQMNIGEDLMLLSKT Falba KYRCPSCRAVTCSLICVRQHRACSGSRPDNQMVKLAHFDLQRDLTFLHEI Fomme1 -------------------------------------------------- Fusgr1 -------------------------------------------------- Galma1 -------------------------------------------------- Ganpr1 -------------------------------------------------- Gloin1 KYKCPKCNFHSCSLKCCKSHKSCEGIRSKVKYVPLEQYGLMSDYVFLEDI Hisca1 -------------------------------------------------- Klula1 KYKCPRCLKKSCSLACSKKHKNCSGISNATEYVSSQNLKVQRDYNFLIGM Lacbi2 -------------------------------------------------- Lenti61 -------------------------------------------------- Malgl1 -------------------------------------------------- Mellp23 IYTCPSCSIRTCSLKCSNQHKNCNGKRNRVTHVPINQYTLMQDYSYLEEV Mnele KYCCPRCKKRTCSLDCVNVHKNCSGVADKASFVKLSEFDMISDYKFLENI Monbr KYRCPKCERKTCSLACVKAHKECDGIRRSRMTREKSELTLWRDYCFLEDA Morel2 KYKCPGCFCQTCSLACSKQHKTCSGVRSRTHFVERKQYTMMSDYNFLEEV Mucci2 IYTCPRCLAHTCSLKCVKQHKACSGERDKTAYVPLQKYTMMSDYTYLEDV Mydma KYTCPACKMKTCCLFCSKKHKNCSGEREKVKYVARSDFNLLNDLRFLEDV Neucr2 -------------------------------------------------- Orpsp11 KYTCPKCLMHTCSLICVKDHKNCDGKRDKVKYVSMNEYNLRNDYYFLEDV Pench1 -------------------------------------------------- Phybl2 KYKCPRCDMRTCSLACVKQHKECSGERSKTHFVPMKQYTMMSDYVYLEDT Picst3 KYTCPACGIRTCCIVCVKRHKECTGVVDKTKFVGRKELVLNRDYNFLLNV Plicr1 -------------------------------------------------- Polpo KYKCPACFVLFCSAECSKQHRDCNGVK--KKFLKLNNSRNNNSYHLI--- Pucgr2 -------------------------------------------------- Punst1 -------------------------------------------------- Rhior3 ---------------------------SRTNRDFISSYTLNRQANYL--- Rhoto1 -------------------------------------------------- Rozal11 KYKCPRCSIKTCSLNCVKKHKECSGQLSRTHFIKVSDFTFKRDIDFISQG Sacce1 KYKCPRCLVQTCSLECSKKHKNCSGQTDPKEYISSEALKVQRDYNYLTQL Salro KYRCPACGTLSCSLPCVKAHKGCTGVRRSQPVKARDNLTLFQDFRLLEEA Schco3 -------------------------------------------------- Schpo1 KYRCPRCDSRFCCLECNLEHKKCSGERDPATFVPKSKLVLNSDFNFLSGV Sorma -------------------------------------------------- Sphar RYTCPGCGVLSCSLVCVTKHKECTGIRVKTSYVSLNSFTLASDYQFLEDV Spipu1 KYKCPGCLCRTCSLACSRSHKGCTGQRDKTQFIKVADYTMTSDYTFLEDI Sporo1 -------------------------------------------------- Stehi1 -------------------------------------------------- Tapde11 KYKCPACVSHTCSLTCSKRHKNCSGKRNQTTFIPRSKFDINNDYNFLTTL Thetr IYTCPRCMVRSCSVACVKRHKGCSGKRDRTKFVPRSAMSVVNDYLLLEDA Treme1 -------------------------------------------------- Trire2 -------------------------------------------------- Umbra1 KYKCPRCAFKSCSLDCSKTHKGCSGERSKTHYVPLKQYSMMSDYGYLEDM Ustma22 -------------------------------------------------- Walse1 -------------------------------------------------- Zygro1 KYKCPKCFKKTCSLPCIKEHKNCSGKSDPTKYVDRGTLKVQRDYQFLTKL [Cluster3909.fasta_al_trimmed; alignment length = 63] Allma1 --------------------------------------------------------------- Ashgo11 QLKGKLIEQQVRRETPKFINALVELCFAQLLGGDLEAFARHAGREV-VASDDVMLRLRKNPEL Aspfu1 RLKSALIGKIVDEETPQFIGALTEMVWTQIVSQDLEFFAKHAGRST-INVSDVMLLARRNEGL Aurde31 --------------------------------------------------------------- Batde5 QLSEPIIRKAIMDATPEFVYALGEVVVRHAMGADLESFAKHAKRSV-ISVDDVKLFARRNIGL Botbo1 --------------------------------------------------------------- Botci1 RLKAALIGKIVEEETNQFIGALTEMVWHQIVTMDLESFSRHAGRST-ITTDDVLLVTRRNDAL Caeel --------------------------------------------------------------- Canalb1 QLKSAVVAKIVEAKTPTFIAQLVELVYNQLLGEDLELFCQHANRDI-VEPSDLFMVTRKNPTL Cangl QLKGKLVDRLLARESQKFVSALVELVYVQLVGETLESYAQHGGRDV-VSMADLRLLLRRSPEL Capow RIKASVVGKICQRESKQFLAALAELTYGKCLASDLESFAKHAKRST-IQVEDVKLCARKNPSL Catan2 ALKTAVVGRIV-------TAAVAKVTHAQLWAQDLAAFAKHRGRST-VSTDDVLLLARRNPSL Cioin KFTQVITGKICKKISKESIAMIADLASRQSFAHDLELFAKHAKRKR-ITADDLFLLTRKTPSL CocheC53 RLKSALIGQFVDDKTPQFIGALTELVYTQITARDLEVFSKHAGRKT-INPDDVLLLGRRNEQL Coere1 --RAAIVAQLCSADTPAFVDALSRVVLSQAMASDLECFARHAKRAK-ISVDDVKLCARRNNSM Conco1 QLKASIVGKICDEESTNFKTVLSQLVTEQLFVKDLEMFSKHAKRSV-INNDDIKLCLRRNPDL Conpu1 --------------------------------------------------------------- Copci --------------------------------------------------------------- Croqu1 ALKAAIVAQIVQEETEPFVASLTELVYAQCLALDLKAFAAHANRST-IRAEDVKLMARKTPEL CryneH991 --------------------------------------------------------------- Crypa2 RLKAALVGKMVDDDTPQFIGALTEMVWTQIVAQDLESFSRHAGRTT-VQTDDVLLLARRNADL Debha1 QLKSAIVSKMVEQDTPTFVASLVELVYNQLLGEDLELFANHAGRST-IKPADLYMVTRKNDIL Dekbr2 -LKASIITKIVEEQTPQLVAALVELVYRQLVGEDLALFANHAGRKT-ITPNDMMMIVRKNPGL Dicdi KIKQSLVIKVSEEQTKETMSSLSELIFNVTVSKDLVSFAQHAKRPTKITVDDVKLLARRNDSL Dmel --------------------------------------------------------------- Enthi --------------------------------------------------------------- Falba LVREAVVASVLEHEEAGFADALAEMVLQQALASDLEGFAWHARRVV-INGDDVRLCARRNPAL Fomme1 --------------------------------------------------------------- Fusgr1 RLKAALVGQIVDEETPQFIGALTELVWTQIVATDLESFSNHAGRST-VTTDDVLLLARKNPDL Galma1 --------------------------------------------------------------- Ganpr1 RLRAALVGKICSNESQQFIAALSELVLTHAMATDLEAFAKHAKRSS-INQDDVRLTCRRNQDM Gloin1 FLKAATVNDICNEETQQFIASLTELVYKQALATNLENFANHANRST-ISINDVKLCSRRNDEL Hisca1 RLKSALIGRIVDDETPQFIGALMEMVWAQIVGQDLEAFAKHAGRST-INLSDVMLLARRNEGL Klula1 QLRGKLVESIIKRENSKYVNTLTELVYQQIVGGDLEAFAQHANRNV-VTSEDMLLRTRKNKDL Lacbi2 --------------------------------------------------------------- Lenti61 --------------------------------------------------------------- Malgl1 --------------------------------------------------------------- Mellp23 ALKSAIVAQIVQEETEPFVASLTDLVYAQCLALDLKAFAAHANRNT-IRAEDVKLVARKTTAL Mnele --------------------------------------------------------------- Monbr --------------------------------------------------------------- Morel2 RLKAAVVGEICNAETPQLIASLAEIVFAQALGKDLEMFAKHAKRST-VNVDDVKLAARRNSSL Mucci2 RLQTAVVNEIVKDQSEAFVASLAEVVMTQMMATDLEAFAVHGKRAV-ISMEDVKLCARRNDSL Mydma QLKAALVGKICEMKSKAFIACLTETVANEVFATDLEAFAKHAKRTT-INIEDVKLLVRRNPGL Neucr2 RLKSALIGKMVDDETPQFIGALTELVWTQIVAIDLETFSQHAGRTT-VTTDDVLLLARRNSDL Orpsp11 --------------------------------------------------------------- Pench1 RLKSALIGKIVDEETPQFIGALTEMVWAQIISQDLESFAKHAGRST-VNVSDVMLLARRNEGL Phybl2 ALYDAMVEQQVIEETPEFIASLTEVVCRQAMALDLEAFAKHAKRNT-ISMDDVKLCARRNPGL Picst3 QLKSTVVAKMVEEQTPIFIASLVDLVYNQILGEDLELFAQHANRST-VKPDDLYMVTRKNDIL Plicr1 --------------------------------------------------------------- Polpo KLKQSFVAKICERETPHAIKTVSELIYQIAVSRDLAMFSKHAKRQI-INGDDVLLMARKNDSV Pucgr2 SLKAAVVAQIAQEESEPFVASLTELVYAQALALELKAFAAHAGRST-IREEDVKLVCRKSSVL Punst1 --------------------------------------------------------------- Rhior3 LLA-------------ALLYNVREIVGKE-MAQDLESFAKHGRRSV-ISMEDVKVK------- Rhoto1 SLKAAVVTKIAQEESEHFVATLAEVVFQQALGKDLERFANHAGRLT-INVDDVKLAARRSEPL Rozal11 --------------------------------------------------------------- Sacce1 QLKARLVEERLQQVTPRFINSLLELAYLQLMGSDLQAFARHAGRGV-VNKSDLMLYLRKQPDL Salro --------------------------------------------------------------- Schco3 --------------------------------------------------------------- Schpo1 RFKAEITQEVCNRTDELFCVGVTEMVWEQILAKDIEAFAEHAGRKT-VQPQDVLLCCRRNEGL Sorma RLKSALIGKMVDDETPQFIGALTELVWTQIVAIDLETFSQHAGRTT-VTTDDVLLLARRNSDL Sphar RLKAAVVGNICDEESREFVAVLALLTFEHAIAGDLEAFSRHAKRNT-VNGDDVLLQMRNSPEI Spipu1 RLRAAVVGKICDEESPHFIHALSELVYQQAMALDLECFSRHGRRTV-ISTEDVKLCARRNDSV Sporo1 --------------------------------------------------------------- Stehi1 --------------------------------------------------------------- Tapde11 --------------------------------------------------------------- Thetr VLTEEMTGVLCEAESTALVGILASLAAGYTVGTDALSFARHGKRKN-VTEKDVLLCARRLPKV Treme1 --------------------------------------------------------------- Trire2 RLKSALIGQIVDEETPQFIGALTEMVWAQIVAIDLETFCNHAGRTT-VTTDDVLLLARKNPDL Umbra1 RLKSAVVGRIAEAESPQFIASLADVVYKQILAMDVEMFAR----------------------- Ustma22 --------------------------------------------------------------- Walse1 --------------------------------------------------------------- Zygro1 --------------------------------------------------------------- [Cluster3911.fasta_al_trimmed; alignment length = 60] Allma1 SFTYQALSYYRYGAKSD--CTAKWEQFKFCLSVKAEEARER-RAVLEAEAKS-LDVWELR Ashgo11 SIGGLVRHYYRHGEFNG--CSKEIERFKFCILHGPVR---QWYREEWEMNKS-EDVWSLR Aspfu1 ------------------------------------------------------------ Aurde31 LLHSQARSLYRYGTRAQ--CSRMFEDWKWCMAFNPERRRER-RAEWWARRRS-EDVWEYR Batde5 TMLPQLKSYYRYGTWKD--CSPQWKEFRLCVSLQPKKEKQRAHAKLKKLEKS-LDVWKLR Botbo1 ALGPQMKSLYRHGTLGN--CDSKLSEFKFCLSLKPEEKRKR-RAKWWASRRS-EDVWEMR Botci1 ------------------------------------------------------------ Caeel ------------------------------------------------------------ Canalb1 ------------------------------------------------------------ Cangl SIGGQFRNYYRYGEFSA--CEKQVNKFKFCILNAPVK---EWYHNQVEENKS-DIVWKER Capow ------------------------------------------------------------ Catan2 ------------------------------------------------------------ Cioin ------------------------------------------------------------ CocheC53 ------------------------------------------------------------ Coere1 TVGSQLRSYYRYGQKSS--CGKHWSKFKMCMGMKSEESGKEFRNKEEAKR-NVMDVWTRR Conco1 ------------------------------------------------------------ Conpu1 VLGTQVKSLYRFGRMAE--CKQKMEDFKFCMSNKPEQRREH-RAEWWAQRRS-EFVWDKR Copci ALRSQVKAIYRYGGRPQ--CSEKADDFKFCLSLKPEEQRER-RAEWWAHRRS-EDVWDIR Croqu1 SLSNQLKSIYRYGELNHT-CSSKLDDFKFCLSLK-DKRAGR-KAE------S-EDVWDRR CryneH991 ALVPQLRNIYRHGELHN--CSWKFQDFKYCMSLKPEGKRKR-RAEWWARRRS-EDVWAVR Crypa2 ------------------------------------------------------------ Debha1 ------------------------------------------------------------ Dekbr2 SMGGQIRNYYRYGDFTM--CDKQTKKLDFCIRNKPNEVKERYYKDRL-IEKS-EDVWESR Dicdi ------------------------------------------------------------ Dmel ------------------------------------------------------------ Enthi ------------------------------------------------------------ Falba ------------------------------------------------------------ Fomme1 ------------------------------------------------------------ Fusgr1 ------------------------------------------------------------ Galma1 VIRAQVKSIYRFGERTS--CERKFQEFKFCLSLKPEEQRDR-RAEWWANRRS-EDVWDMR Ganpr1 AVIPQMRSFYRHGKRKD--CSHYRSEFAFCSRVRNSEDAQQEHERERYIRNSVGTIWELR Gloin1 TIGGQAINYYRYGERKS--CKSKWEDLKFCLQLKPIDIRKLERESLKEEQKS-LDVWEIR Hisca1 ------------------------------------------------------------ Klula1 SLGGQFRNYYRHGHMNE--CLKEFEKFKFCVIHSPVK---EWHKEQWQKNQS-DDIWKER Lacbi2 VIRSQIKSLYRYGERPE--CASKLEDFKFCLTLKPEEQYER-RAEWWAGRRS-EDVWDIR Lenti61 VMSSQFKSLYRYGEMAT--CSPKLEEFKFCMSLKPEEKRDR-RAEWWARRRS-EDIWDVR Malgl1 ALGEQFRSVYRYGTIAN--CAPRREDFKFCLTLRPETRRAR-RAEASAHQRS-EAVWEMR Mellp23 ------------------------------------------------------------ Mnele ------------------------------------------------------------ Monbr ------------------------------------------------------------ Morel2 SLGSNIRNYYRYGTFKD--CAARYDHLKFCLSIKSSQVAQKRDADLRAHKKS-EDVWSLR Mucci2 TLGSQAINYYRYGTKKD--CSGKWDDFKFCLKTKSSEIADKEHQAAKESLKS-EEVWEAR Mydma ------------------------------------------------------------ Neucr2 ------------------------------------------------------------ Orpsp11 ------------------------------------------------------------ Pench1 ------------------------------------------------------------ Phybl2 TLGSQAVNYYRYGEKKD--CSVRWDDFKFCMSAKSSEVADRQRAKEKERLKS-EEVWEAY Picst3 ------------------------------------------------------------ Plicr1 VLGVQLKSLYRFGHTSV--CAPKMEDFKFCMSIKPEEKRDR-RAEWWAQRRS-EDVWDIR Polpo ------------------------------------------------------------ Pucgr2 SVSNQIKAIYRFGNLDYERCNHSFRDLKFCLNLKDDQQSFR-KAE------S-QDVWEAR Punst1 ILGKQLKSLYRYGRTSD--CSQKLSDFKFCMSNKPEEKRDR-RAEWWAGRRS-EDVWEVR Rhior3 RVKEQAKHYYRYGTKKD--CEAKWDYFSVCFSTKSAEKADKAHREATEEKKS-EDIWERR Rhoto1 SLGSQFKSIYRHGSTRD--CTPKFEDFKFCMSMRDEKREDR-RAEWWARRRS-EDVWDAR Rozal11 ------------------------------------------------------------ Sacce1 SIGGQFRSYYRYGDFTS--CDKQVSKFKFCIIHGPVK---EWYKDQVSNNKS-GVIWQER Salro ------------------------------------------------------------ Schco3 SLRENVKAIYRYGHQTS--CSEKAAEFKWCISNVDEERHDR-RAEWWARRRS-EDVWEAR Schpo1 TVFSQMNHYYRYGEYNR--CKGNFKDFKWCLSTKAHEEAQKRRLQQWMKFRS-EDIWKMR Sorma ------------------------------------------------------------ Sphar ------------------------------------------------------------ Spipu1 TVLPQVKHYYRYGSWRD--CSEAREEFNFCLRMKNRKEAEREREETKYDKKS-RAVWELR Sporo1 SLASQTKSVYRHGAPRN--CSPKFEDFKFCMSVKEERKEQR-RAEWWAERRS-EDVWDAK Stehi1 LLGNQFRSLWRYGQSAN--CTTKLQDFKFCMSIAPDEKRER-RAEWWARRRS-ENVWEAR Tapde11 TPKSQLRNWYRYGEKKD--CAERWRDLKWCMTTKDEDASQERKVFMDAKVHS-EDVWDLR Thetr APGNYFTTYYRTGSFVD--CSAEWAAFKACTRVAGAYRAKR----------N-GHVLKLR Treme1 ALVPQIRNMYRHGELRD--CSHKLQDFKYCLSLREDAKRQR-RAAWWASRRS-EDVWDLR Trire2 ------------------------------------------------------------ Umbra1 TLGEQAINYYRYGEKKD--CSGKWDYFKLCISTKSPLHAKDEHKAKTEEEKS-EDVWTLK Ustma22 ALGPQLKAVYRYGGLQD--CKAKLDDFKHCLTMKTEDKYER-KAEKTAEKRA-ENVWELR Walse1 TLRPQLLSIYRYAEYKK--CDRPWDDFKWCFFNNDEQKLKR-RADWWARRRS-EDVWDAR Zygro1 SVGGQFRTYYRYGEFNA--CQKQLAKLKFCMFHGPIA---QWHKEQIEFNQA-DDIWQER [Cluster3913.fasta_al_trimmed; alignment length = 85] Allma1 IGRAVLILGLLVLCHAAYSAFEHVSYLKTIEALLAMIVSTVGILLVADPLQDISLENELKQKTR-HAFESRPSFRSF-GHRGPHF Ashgo11 ------------------------------------------------------------------------------------- Aspfu1 ------------------------------------------------------------------------------------- Aurde31 LGNALLLVAMVLTLHTAFSTYEHLSILKALEAFAALFLGIFGAALKTPALKEITWASEMKARSI-DEFDSRLSFMTL-NHRGAKL Batde5 LACLLFSAGIILLLHAGYSAINHFAYLKTIEILVSIVVFSQGAVMVAGDLKPISLQLELSQKTM-DWVDATPGFKIV-NHRGSAL Botbo1 LGRSLLALSTLILFHAAYSAYEHLTFLKAIESLLALLLFTFGAVFNAPPLKEITWASEMSKRSI-DEMDSRLGFMSV-NHRGKML Botci1 ------------------------------------------------------------------------------------- Caeel IYRLITIVSLLSLLHCAYSAAQHRFYLRLTQTVISLIALIYGTSFLANPFLFIKKDQHHDR----DEALNCPSFITF-DNRAKAM Canalb1 ------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------- Capow LTRVAFVLGALLLFNAAYSTVQYRNFLKMAQTLAAMVLATWAIVEYTAPFKNIHGSNERVR----DAVDNRPIFYSF-QHRGALL Catan2 FGRLVILLSLALLAHAGYSAFEHIAYLKSTEALVATALCLVGLVLVADPLMEIALESELSKQSR-DVFDARPSYRSL-GHRGRHF Cioin ------------------------------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------------- Coere1 -ARGVAVAAFLAMLHSGFSAREYLRYSKSIECLISLVIMTVAVVVGVGILRPVSYEAEMKRYSI-DGIYSRPSFQVF-NHRGRFL Conco1 ------------------------------------------------------------------------------------- Conpu1 FGRLFLVVATFALIHAAYSTYEHLSRLKALESVFALILGILGAALNAPTLKDITWAGEMKKRTI-DEMDTRLGFANY-NTRARHL Copci LGRALLLFSTCLILHAAFSTYEHLSYLKALETLIAMVLGILGASLNAPPLKEITWASEMRKRSI-DEMDSRLGFASY-INRGRNI Croqu1 LNRILILVGSGLFFNSAYSIYFERIVLHS-QMGISFILLIIGTILSSPPLKDIHWKTQLKQRSI-DEFDAKMGFINL-NNRGHLL CryneH991 IGRLLVGLACLALFHAAFSTYEHLSILKAL------------------------------------------------------- Crypa2 ------------------------------------------------------------------------------------- Debha1 ------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------- Dicdi IAKIFCVIGISIFLHTVYSALQHRKYLRLTECIISLFLFAWGIIN-SQFLIPIKASTHLAKKSF-DSYDYRPNFTVF-NHRGKYL Dmel FNKLLLIAGFASLAHAAFSAAHHRTYLRLTQTVISLVIVIYNIIEIVGNFKEIRATVDMQQKTW-DTLGNFPSFYSF-NHRGRAL Enthi ------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------- Fomme1 LGRVLLTVAILALLHAAFSTYEHLSHLKALEALVSLILGIIGASLNAPELKEITWRSEMRKRKI-DDMDSRLSFASW-TNRGNEL Fusgr1 ------------------------------------------------------------------------------------- Galma1 LGRVFLFVATIAIFHAAFSTYEHLSRLKALETFIALLLGILGACLTTPPFKEITWSSEMRKHKI-DEMDSRLGFASY-VNRGKQM Ganpr1 LARLALLSGFILLLHSAYSAAEHVAFLKAVECLVGTLLAILGIVGTSGTLKPVLLEHEMDKKPY-DSIDNNVSFRPM-MHRRRAR Gloin1 IGKILGWIGFITLIHSTYSTYEHLSYLKAVECLFSVIIFAISVILVAGPLKPILMKSEMVKKSI-DKVDTRPSFNTF-NHRGRII Hisca1 ------------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------------- Lacbi2 ------------------------------ETLLAVVLGIIGASLNAPKLKEITWASEMRKHKI-DEMDSRLGFANY-VSRGKIL Lenti61 LGGLMLIVATIALLHAAYSTYEHLSHLKALEAAAALVFAIVGATVRSPPLREVTWRSEMKRRALEEEEDPRMSFAKF-AQRAGIV Malgl1 RGRLTTIAGIVLFLHAAYSAYEVLSQGKSIETLVAFVVLVVGCAMTTPKLRQMTWTARMRETDI-DLVDARPSFATV-YHRGAKL Mellp23 FNRMLLLIGSGLFLNSAYSVYAERILLHG-QLSISFIIITIGIILSSPNLQDIYWKTQLKKRSI-DEFDSKLGFINL-QNRSSIL Mnele ---MLMI------LHAGLGSAHHRANLRLSQCVIGFVIACFGISKVAGEFKDISATNDLNRKTL-DSITNVPSFYHF-AHRGRSI Monbr VSLALGLLGCLSMFHAAYGASQYRNFLKVTESLAGLTLIMVATVLAKIDFTLIHIAAQLRDKVY-YTACGKPSLRPLRTSRLTYM Morel2 FGRLVCLVAFFLFFHSGYSTFEHLSYLKAVELLTSVALFGLGIVLVADDFKEILMETEMAKQSI-ESLDARPSFYAF-NHRGRAV Mucci2 IGKLIALIGALFLAHSAYSTYEHLAYIKAVECLASALVALVGVVFSVDAFKPIAVETEVAKMTI-DKIDTRPSFVTF-NH--RKV Mydma LGRCLVTVGIISLIHCGYSAIQYRTYLKLIQVLVSVLISIFGIIRIAGELKDIHAAAELASKSW-ETLGNRASFFTF-THRGQQL Neucr2 ------------------------------------------------------------------------------------- Orpsp11 ------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------- Phybl2 LGRLIGLIGTLFLAHAAYSTYEHLAYLKAVECLVSAIVTLIGVLLSADSFKNILMEAEIAKQTI-DKIDTRPSFITF-NH--RKV Picst3 ------------------------------------------------------------------------------------- Plicr1 LGRIFVVLATLAIFHAAFSTYEHLSHLKALEALLALVFGTIGASCNAPELKEITWASEMKKCSI-DGMDSRMGFANF-VSRGKSF Polpo LSLIICTIGIALLAHSVLSALQHRSYLRLTESIVALLVSSWGIINLAPKLIPIKATHHLSKRSY-ESIDYRPDFIQF-NNRARYL Pucgr2 LHQLLISLGGVLFCHGAYSVYVERILLHG-QLAASFLLLVTGITLSAPPLKNIHWKAELKQRSI-DGFDSKMGFINL-NTKLATL Punst1 FAQVLLFLATLSLLH-------DLSHLKALEAIVSLVLGTIGASMRAPTLKEITWASEMKTRTV-EEMNTRLGF----------- Rhior3 ------------------------------------------------------------------------------------- Rhoto1 LARLVILVSSMVLLHSAYSAWQARIAADTGEAVSSFITLVIGILWSAPALKGVTFASEMSSRSV-DSTDSGIAFANV-RHRGSLL Rozal11 ------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------- Salro GGWVGVSISVVLLLHAAYSASRYHSYLKINQTVAAMIVGMVAIVALNTNFADIHLTSRLKSKTW-ETACPKAAFRTF-HNTRHSL Schco3 LGRLMLFAALLLVLHTAYSTYEHLSHLKAMEAFIALILGTLGACLRIPPLKEISWASEMRTRTI-DDFDSRLGFASY-VNRGKHI Schpo1 ------------------------------------------------------------------------------------- Sorma ------------------------------------------------------------------------------------- Sphar ------------------------------------------------------------------------------------- Spipu1 IGRLFYTIGAILLVHSGYSAFEHLAYIKVIECLLSVLLCILGVVLVAGDLRPISLEKQLSRMTL-DTIDMRPSFRTL-HHRGKAI Sporo1 ------------------------------------------------------------------------------------- Stehi1 ------------------------------------------------------------------------------------- Tapde11 ------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------- Treme1 LGRILAGVACVALFHSAFSTYEYLSILKTLEVIGALGLFLVGTALGTAELKDVTFRGELARRDT-EDYDPQMAFTIL-SPRAKPL Trire2 ------------------------------------------------------------------------------------- Umbra1 IGRLLSLVGITFLIHSAYSTYQHLSYLNAVECLISVVVSLVGVVLCAGDLKNILMENEMRKQTI-DKLDTAPSFITF-NHRGRRA Ustma22 TGRLLLAIGTLVFFHAAYSTYEHLSLRKSLETLVAFIVILIGIALTAAPLKNVTWASEMRTKSI-DEVDSRSNFASL-THRGQIL Walse1 ------------------------------------------------------------------------------------- Zygro1 ------------------------------------------------------------------------------------- [Cluster3916.fasta_al_trimmed; alignment length = 187] Allma1 PRPDL-AVHAAA--YAAILLHALKHV-HKPVFGVLLATTT------AISRVVPVSHTPLARTACLLEVALEQVRKYTAADKNVVVAGLYYADAGA-DADA--NVATQVLESLGV--EGVLLRLNTTKLPYALAPTR------------IRLVEPPKNLPKVLG-PLNQLFDFDDHLEDVA-RDWLSN Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 -MASY-TLSHQA--YLKVVFHAAQHP-HKPVNGVLLGQ--GSGGRVEIVDTVPLLHHWTSLSP-SMEIGLDLAYGH-AEAAGLNIVGYYQATDRT-D-DT--ALGERVASRIKEP-SAVALVIDGEALSIALVPY----SQAGAGWKR--LASPARTLELIRDNGLHRLADFDDHLEDVA-LDWLRN Batde5 SVSSY-HISNKA--YAKILLHSAKYS-MDPVYGVLLGSLNSSDGSVVVSDVVPMFHSHWILSP-SMQFGMEQIEIY-AKQTGLAIVGSYSGNE---A-ST-LSVVAKAASDIDAQGGALLLMLDVACITFAVIPLT----LQNTTWKPTPATHDDSYAMGLIKRSLYNIYDLDNHLEDIS-LNWLTN Botbo1 MPASY-QLSNLA--YLKLYLHAAKFP-HAPANGVLLGSL-TSPDQVLISDAIPLLHEWTSLSP-MMEIGLDLARGH-AEGSGLTLVGYYQASEQS-DNDT--SLGERVANIVRES-DAIALVIDAKKIDPALVPFLPTTSDP-KVWRPARLVDPSRALASVRDDSLHQLYDFDEHLEDVK-LDWLRN Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel --MKH-QVETQALPYSTIILHCLKYP-AKGVFGLLIGNKK--GDKVTVTSCVPLCHESTPLAP-PLELATALVHG----KFGASLVGVYFSNA---S-DT--SLATRLADRISSS-AAILVQVMNERLQDRLVAYE----KDGDSWKE-------RGLQAVIQKKLYRLSDFENHLDNPE-FDFYNT Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow --MRTVQLARDA--YAKIILHAARFP-SSGVNGILLGTPISSKRDFKVTDAIPLFHSQLNLAP-MLEFALHAVYAY-AQKHQLSIVGYYQASETI-G-SG--SIAQVVGDRIRAP-DAVVFMVDNRSINLALNPFI----HTGSAWRQLRLSPIDKFVVDHIKRKTFRIVDFQTHLEDVS-LDWLN- Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ---HPVEVSCKA--FTKLQLHAAKYP-HCAINGLLVACKQKESKAIEIVDAIPLFHQCIELTP-MLEIALTHVDAH-CHANDLFVAGYYEAPQHLPS-SI--EPGSKIADKIHGE-SVLLVVIDNKRIDSVNFFEK----ANEGKWKRITFQEN-PVLMHLLNRKVARIVDFDNHLDDIS-AHWLNH CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 -MSKR-TISVQA--YAKAVLHCAKYP-WATVHGLLLSEKKG---KVRYVDAIPLAHTWTHLTP-MFDVALQQVQLY-AKANGLSIGGYYVAHEDV-S-AT--QLSALLAKTILGD-DVVAFVIDAKKLEPGIIPYV----NTDSQWKAFALENNRATAKRLVAERAEVIHDFDEHLDDVT-LDWLQN Conco1 MSKRLQFVSPQS--YRKIVAHSFRFQ-NNNVFGFLLGKLN--NEAYTVHDYTPVSHNWTSLSP-ITEAALQQVTIH-AKEKNLSILGLYYASEDL-N-GT--EFLKLLMNQLSAEFKPILLTIDPSKLEVVLIGYT----LTKDQYTPSVITPGEGLIKSLDSRASAPINDFESSLDNVDDVNWLDQ Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci PAPNL-TVASKA--YLKIYFHAAKHL-HQTINGVLLGNQ--TGGKIVVEDAIPLLHHWTSLSP-MMEIGLDLAEQY-AAEANLKIVGYYQGRAAV-G-DV--GLGEKITQRIKEA-DAFALTLDGEDFKAALVTY----TEN--QWRRIQLDSPDKALSYVRDKSLHLFGDFDDHLEDVK-IDWIHN Croqu1 -MSTF-TLSNKS--ATKSILHATKYS-HSTVIGLLLGNLDEETKTISISDVIPLIHHWSDLSP-ILEAGLNIANEY-AVSIGLIIVGTYIAKERI-D-DT--SLSKSINQSIS-D-QPIALVIDNNKLQNPFLSFVFSE----------------PPFNEMHQ--LCNISDFDDHLNDIG-LDWLVN CryneH991 PSYSY-SITPTA--YSLPILHAAAQP-SSTVIGVLLSSSSPQDSKQVVDDAVPILHHYTSLSP-MMEAGLSIVGKY-AEINRKRIVGVYVARDE----GN--GLVERVWKILREE-GAFALAIDNGKLQPAYIPYLPTEASP-YLLHAFSVSSQSSLLKVIREKKIHRLRDFDDHLEDSK-LND--- Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi -MNNNISITTEA--LSKAHLHSFKHH-ASSVNGILLGKAD--KNSILITDIIPLFHTQT-LLP-MFEVAMIQIEKY-CRDNNIDMVGYYHSNQNE-L-EP--EPAKKIADRLNNN-NMCFLMISKIE-PSGLVSID---KVGSD-WLKTLITIDTEILKRNLQNIKESIYDFEEYLSNPT-RDWLNK Dmel -MCDY-KVSERA--YAKLIFHAAKYP-HQAVNGLLLAEK-SKGSQVEIVDAIPLFHQCLYVTP-MAEVALMLIDAH-AEREGLVIAGYYAAPENFYD-NQ--VDAAKIADKIQEK-NACFVVVDNKLMRAAIQVFNC-PGDSGARWSKFTLSQASEGVSLLLKRGAMRLVDFDNHLDNPD-KNWTND Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba ----MFRLQQAS--ISPVACHAAAHG-DAVVQGALIGRIRLAPVFIDIIDAIPLSHTSPGTSP-TLEFGLSLAANF-AASQGMQLVGTYYFGA-----SLWPLVASAEGDSLPEA-QAVLVTSNNLMLLPSLLPAAPGSSSSSQQQQPASLLSPAGPLSPTAGAGAGALRDFDQSLDDPR-ADWTNP Fomme1 ---SF-VVHKQA--YAKIAFHAAKYP-HRQVNGLLVGKE-KSGS-IEFTDAIPLLHHWTNLSP-SMEIGLDLASNY-AQSNGLEVAGFYQVSEHI-T-DT--TLGEKVADTIRKP-NAVAFVVDGSKLEPALIKY----STS---WRPFKLSTPNSILRLIREDRIHQLGDFDEHLEDVS-IDWLRN Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 SKASY-TISPEA--YYKVFFHAAKHP-HQPVNGVLLGTQDSAGA-VDIQDAVPLLHHWTSLSP-MMEIGLDLATQH-AESLDMKVVGYYQACERV-D-DT--ALGEKVASKIKAD-DAVAFAIDNQKLQSALVPYLASSSMS--GWRPFKLSLSDEAAKYVQEQNLHFFGDFDDHLEDVT-IDWLRN Ganpr1 -MSNY-TVNLKS--YKKVILHACKYPYASNINGLLIGTKRGEGEDIAVLDAIPLFHTNVNLTP-MLEIATSQAEQY-ATSKGLQIVGYYHANLA----DK--APATKIAATLDHGYNVLLLMVDPWKLDYAVVAYT----RDGAAWKNFQIADK---------RADIELHDFDEHLDNLK-LDWLSN Gloin1 -MPEY-IINKEA--YLKIILHACKYP-SSTVNGVLLAQEEDDSNKIIIADAIPLFHHWNTLTP-MLEVGLQQIEIY-AERNKLNIIGYYHANERV-D-DN--KLGQKIASKILENINAISLLVQNSKLEIAIMPYI----FKENQWRPFALDNNDKLVSSSICKKHFELYDFDEHLENIE-LDWLNN Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 MPASY-TISAQA--YYKIFFHAAKHP-HRAVNGVLVGKQTSSGGEVEISDAIPLLHHWTSLSP-MMEIGLDLAGEY-ATSSGMKLVGYYQACERL-D-ET--ALGEKVAGRVQAG-DAIAFVIDGEKIVAALIPYTFQPSSK--AWRPFKLASNDQAISLVQDQHLHQFGDFDDHLEDVA-IDWLQN Lenti61 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 SASQSVDVSPLA--YRKIVYHSAKYL-SSTVVGVLVGTKSSNKPNTTVTDIIPLVHHWHTLSP-MTEAGMALVEAH-LGKTGGTLLGLYEVPERL---DQ-KIPTTALAETLEKGTAPLVLHMNGAKLIHATV---------------AQVARPELALSQELDQGAWKLYDWDDHLENTQ-LDWLTN Mellp23 -MFAY-SLLPKS--AIKAILHASKYP-HSTVIGLLLGSIENE--SVSISDAIPLVHHWSDLSP-MLEAGLAIADGH-ARSSNLMIVGTYVARARL-D-DR--ALSQQLNSLLE-K-HPIALVIDNTKLENPFIPFLMTDSQG--SW---------KTLTSCQP----TLADFDDHLEDIG-LDWLVN Mnele ----------------------MQYP-YTAVNGILLTKDGEDKEMIDVVDCVPLFHYNIPLSP-MFIVALTQIEEY-ASNRDLKICGYYHANE---S-DS--EVATKIADKIAEE-DSALLIVENDKLDLPLKAFLPSKTNERVDWRSPRLQYGEQMGPEVVKKQLYRVVDMDCHYDNIS-LHWDNR Monbr ----MALITSDA--YFKLLAHACKYP-FDTCLGLLVGQR-GADGSVTVQDVVPVLHSQHQLAM-VMHAALAQVDMH-YQDSPVSLVGLYQVHDRV---DAKLQMARKIAARLRQP-HAVALVFDSQNLAAALFP------QEKDEWMHLQFTDSDQRLSKMLESRSYEIHDFEEFLADGT-SDYLNA Morel2 ----M-KFSHKA--YLKPLAHATKYP-TGPVNGVFLAET-NSAN---VIDAVPFFHFWGALTP-MLEVAMTQVDLH-CKANGLRIIGYYEANERL-E-DE--AFGQKIASQIHHP-EAFAVVIKNNKIEVAFLPY----QFKEGQWRVFSLENSSVVAKALRG-GLSELADFDNHLENIK-EDWLTN Mucci2 -MVQTNTVDLHA--YAIPLLHAAKYP-SSDVCGVLLGKN--SADGLLVNTAIPFFHHWTTVTP-MLEIALKQVDLY-AKKNDLSIVGWYHGNARN-D-DN--ALAIKVTETIKRQDKAIIFLINNKQFESAITPFV----HADNQWRKATLSEKDSKVRGLFSSSAYNIYDFDEHVDDVS-LNWLEI Mydma --MDI-SFSPRS--YSKILLHATRYP-HKAVNGVLLGVCDNDNGKMRILDAIPLFHQCLGLAP-MLEVALTQIDFY-CQRQKINIVGYYQANENI-E-DK--SPAYKIAEKVNDK-RSILVMLDNSKMEVALDVYS----ISDNKWR-WQLVGGDALVSELIIGKTFQLIDFDNHLDDIS-QDWLNI Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 --MEY-HISTEA--YLKIFAHCIKYP-VNQVTGILVGKKTGSPSKLNVINAIPVSHESILLSH-NIEIALKQ------------------------------------------------------------------------------------------------------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 MSIQY-KVSPRA--YALPILHAAKYS-SSTVCGVLLGKV--DAQEVEVVSAIPFFHHWTALTP-MLETALQQAEIY-ATLNDLKIVGWYQANEHD-D-DV--TVAIKVTDLIRQP-QAVIFIVDDRKTESSILPYI----FSENQWRAFGFTYEEPKVRGLFSTSAYNVVDFDDHLEDVS-LDWFTS Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 SGNTY-TVAYNA--YLKIFLHAAKHP-HKPVNGVLLGNASGSGK-VTIDDAIPLLHHWTSLSP-MMEIGLDLARTH-ASARGLQLVGYYQACERL-D-ET--ALGERVAGKLRED-GAIAFVIDGEKLDAALIPYLPSSATS-ASWRP--LADPSRAVAAVHARA-HAFGDFDDHLEDVS-VDWLKN Polpo --MSEITISLQS--FLKIHSHSFKYC-TNAVNGILLGYVE--KSVLNITDVIPLSHSMT-LLP-MFEVALIQIEAY-CKINQIEMIGYYYANENT-F-EKDLEPAKRVADKLYNN-SMCFLGVTEIN-PLGLIPIG---RNNENQWVKLRLTGDKSMIQAHVKDGKLTFNDFEDYLNNPT-LDWLNR Pucgr2 MAKSY-VIQSLP--ALKILRHLAKYP-HSTVIGLLVGTIDGD--RVTILDAIPLVHHWLDLSP-MLEAGLALAKIH-VESKNLKLLGTYVAHSRT-D-LK--SLSQRLNESLQ-D-SSIALVIDSTKLDNPFIPYTRSK-DS--EW---------KDWLHCE-----GIGDFDDHLEDLG-VDWLVN Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 -MVDY-SIASLA--YLKLVLHAAKFP-SSTCVGLLIGTV--AGSSCTITDAVPLLHHWTNLSP-MAEAGLGLAELY-AKQQQLVFLGLYVANERL-G-NQ--AVAQKMAEAIRRP-EAVVLVVDNEKLEPALIPYLPPKSPS-AAWQPISLADSSKALEQVRQGR-HKLGDFDEHLEDVR-VDWLRN Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -----MRIHAAA--YVKAVCHASKHS-FGAVNGVLLGLVHNGRQEVEVVDVLPMLHQHTTLNM-LAQMALSQADAY-ARSKDMRIVGYYHASARA---SS-CELGPLIADKIHSN-GAVALVANFGKLDCRLFPFK---KGSDGKWKRVMLPTEEQTAAEFVASGAHELVDFDDHVADVS-RDWLNE Schco3 -MPSY-TFSDDA--YLKLFFHCAKYP-HRAVNGVLLGTE--AGDEVQITDAVPLLHHWTHLSP-MMEIGLDLAATY-AASVGMKLVGYYQACERL-D-DT--ALGEKVARRIRDA-NAAAFVIDGEQISAALVPYTFNTSTS--SWTRYRLTSTDRAVKLVRQEQREKFGDFDDHLEDVT-IDWLRN Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar --MLY-QVEKKA--HAKMVLHALKNA-HTAVNGVLIGTST--ADKVTVADAIPLFHTRLMLPA-MAEVALAQSAAY-SDEKGLEIVGYYHGDESMPT-DN-TNAANKIHDKCR---SACVLMLNNANF-----P-------------------------------------FDSVLQKE-------- Spipu1 -MSQSYTLHTLA--YTVFLLHSAKYA-VHSVSGVLLGKKT--SKGIEITDAVPCFHGEV-LKG-SLEIAFQQIEIY-ATQTSTQIIGFYTANLNA-A-DK--EPVTRIMDTIDES-GAVLLVVS-------------------------------SILVH--------------------------- Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 SGPSY-AVSDLA--YTKIILHALKHP-HQPVNGVLLGSPSSSGV-VEIVDTIPLLHHWTSLSP-MMEIGLDLARSH-AEGRALKLVGYYQATDRI-T-EA--VLGERVASSVRDA-DAVAIVVDGGKLESPLVPYLPSSSSTPASWRP--LRLSMRAPGLLQD-----FGDFDDHLEDVT-VDWLRN Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ----MVELSKGA--AGKIVCHARQHV-TRAVVGLLLGQ--DA-----VTDVVPLAHTLLALTA-VEEAALNMIEAH-AASQDLAIVGVYYGNARQDDCSVPPAVSSAVGGCI-----VAAAVADHIPLLP---PLALT----------AAAAAAAAALAPTVA-----IADYDDHMDSLV-HDWRNP Treme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 -MVKY-TVNERA--YALPLLHAAKYP-SSEVCGILLAEASSDSETVNITQAVPLFHHWTTLTP-MLEVALQQVDLY-ATKNKLEIVGWYVANENN-T-DR--SLTIKTIDKISRK-NAVVFLIDNDNIESAILPHI----KNGGQWQHFQLTNVDAKVRGLISNGQYKLVDFDIHLEDVS-ADWLTN Ustma22 TTASV-RVSPLA--YKKLILHTAKYP-TARVLGFLVAES-TSSQSIDIVDSIPLSHHWTALAP-MAEVALALASSY-ASSKNLAIVGLYEAPELI-A-ER--DPASKLAEKIASA-EALLLLVNNATLHHSLSGYSVAATSGKGEAKPVALQDPRELESAVRNDSTWDIVDFDDHLEDPS-LDWLHN Walse1 -----MSINAQI--HSKIIAHAGKYP-ECAINGILIGRLD--DKNVELVDAIPVQHLWNKLSP-VLEMALQLVEIH-ANSLNLQIVGLYEASELI---DQHPTLTTHILNKIKSSKHVVGIAVDNRIIEAGLH----------------SLASHNQ------------------------------- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3927.fasta_al_trimmed; alignment length = 174] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aurde31 LLLVLADGNLPTGAFVASSGLESFIAHGDFIRDSLESYASSALSFVQQVHTTC-LNTVTRRASTAQGVALLTLYTRGLALIDELKLLVRKGHLPVCWALLTACLGLSCDRTLYLHLFLHARGVLSAAIRLNTIGPYAAQQLLLVRPLLDPACTWPLGEILAARHDLQHSRIFNS Batde5 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Botbo1 LLLLLSDGNLPTGSFVASSGLESLVKHGNFIRDSLQSNAHSTLPFISHAESMT-LNHVTRRASKAQGVALLTLFSKGFAVVDAFKTMVRRGHLPTCWAVLTASLGLSLSRSQHLHLFLHARAVLSASIRLNTMGPYAAQQLLLVRPLVDPATTWPLGEILAARHDLQHSRIFNS Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CocheC53 ALLLLADSALPLGSFAFSSGLESYLAHHTFLRLSLSTLASTSLPYVFAGDAST-PCTVARRASIAQGRALLAVWDRSFRALASFSAALRTAHLAPLWGLITSILHVPLQQAAYLFLFSHARTVVSAAVRASVMGPYQAQAVLALQERIRAGQSVPVMDLWVGRHEKLYSRIFNS Coere1 LLWLLADSQLPTGGFVASAGLEAAMQAGEFIRRSTQNQVRFALPFCSQAHAMVSSNSVAMRASVAQGGGLLSLFNRGYAVAKRLQRLSRLAHWPTVFGFVCVALGIGLEHAQQLYMFQFVRQIFSAAIRLNLVGPLRAQALECMQQLVDAVYTEPILELFQGMHDRLYSRIFNS Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Conpu1 ILLLLSDSNLPTGSFVASAGLESYGKHGTFVRESLATYARSALPFVSDAETTT-LNHVAKRASAAQGVALLTLYSKGFSLIDKFKMMVRRGHLPVCWGVLTGALGLSLERAQYLHLFLHARGLLSSAVRLNTMGPYSAQQHILVKPWIEPATTWPLGEILAARHDLQHSRIFNS Copci LLLLLSDSNLPTGAFVASSGLESYLKHGAFLRDSLASYGRTSLPFVSDVEAQT-LNHVARRASKAQGAALLTLYTKGFSVVEQFKLRVRRGHMPICWGVLTAALSLSLDRSQYLHLFLHARGLLSAAIRLNEVGPYNAQQTLLVQPLIKPANTWPLGEILATRHDLQHSRIFNS Croqu1 LINILSDSNLPVGGFVSSSGLESFISHSSFTRSSLLNYASLAIPFMNGLHAMC-LNPVTRRSSLAQGSAMILLYTKAFSIIRHLKDRLQPIHLPIAYALVSGLLGLSRARAIDLHMFLYVRSILSAAVRLNLIGPYLSQRILFVRPMLDPTSTWPLGDILAARHDLCHVRLFNS CryneH991 LLYVLTDSNLPTGGFVSSSGLESFAKHGDFARAEVSNYASTTGGFVMDGECTL-LSHVGRRSSKAQGVAMLTLFSRGLSIVEGYKKMVILGHLAVCWGVITAALGLPVDRALHLHLFLHARSLLSSAVRLNIIGPYASSQLLLYRDIINPATTWPLGEVLMGRHDIQHSRIFNS Crypa2 FLLLLSDSALPLGSFAFSSGLESYLAHSLFLPLSLSSYASTTLPFLLAADAAV-VCTVGKRASTAQGRALLGIWDRSFAALASYSELLRSAHLAPLFGLITSIVGLSLHQAAYVFMLGHVKALVSAAVRANLMGPYAAQKVLATQAMITAGQSVPVMDLWVGRHELLYSRIFNS Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fomme1 IMLLLADGNLPTGSFVASSGLESYLKHGNFVEDNLGSYAHSALPFVSDAHSMT-LNTVTRRASKAQGVALLTLFSKGLTLVADYKLRVRRGHLPICWGILTAALGLSLERSQYLHLFLQARSLLSAAIRLNSLGPYAAQQILLVKDLVEAATTWPLGEILAARHDLQHSRIFNS Fusgr1 FLLLLSDSALPLGSFAFSSGLESYLAHQSFLPASLSSFAATTLPFVLAGDAAI-ICTVGRRASVAQGRALLGIWDRSFRALKEFAAMLRQAHLAPLFGAVCALVGLGLRQTAYVFMLSHVKALISAAVRANVFGPYHAQKVLAVQRMIDAGQTVPAMDLWIGRHEILYSRIFNS Galma1 ILLLLSDSNLPTGSFVASSGLESYLKHGDFIRDSLASYARSALPFVSDAQAMT-LNHVARRASMSQGVALLTLYSKGFSLLDQFKLMVRKGHLPICWGALTAALGLALERSQYLHLFLHARSLLSASVRLNDLGPYGAQQILLVRPLVAPANTWPLGEILAGRHDLQHSRIFNS Ganpr1 LLYQLADSALPTGGFIASAGLEAATTSGRFLASSIHTYAHSTTPYVERAEACT-SSAVARRASSAQGGAMLMLFSKSFAIVDAFKLAVRRGHLPVCFGIIARCLDLELANATHLNLFLHTRTLLSSAVRLNLVGPYLAQRVL-------------------------------- Gloin1 LLWQFADSALPTGGFVASSGLEVAVQSGIFLSSSIENYAYSALPFVTDSETCT-SNVITKRASKAQGVAMLTLFSKSFGIIDKFKFEVRKGHLPVAFGLVSKCLGISLERAQHLFLFLFSRAALSAAVRLNIVGPYYAQRILTCHSYVEAVQTSPILDILQGRHDKLYSRLFNS Hisca1 ALLLLSDSALPLGAFAYSSGLESYLAHILFLSFSLASLASTTLPYVLTADAST-PCTVTRRASIAQGLALLSAWERAFRALSSFSTTLKTGHLPPLWAVVCVAMDIDITSTAYVYMLNHAKAVLSAAVRASVMGPYQAQAVLALREVIEAGQVVPTIDLWVGRHELLYSRIFNS Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 LLLLLADSNLPTGSFVASSGLESYLKHGAFITDSLASYARSTLPFVSDANSMT-LNHVARRASKAQGVALLTLYSKGFALFSQFKLSVRKGHLPTCWGALTAALGLALDRAQYLHLFLHARSLLSASVRLNDIGPYGAQQILLLRPLITPANTWPLGEILASRHDLQHSRIFNS Lenti61 ILLLLSDSNLPTGSFVASAGLESYVTHGNFLRDSLSTYGHSALPFVLDTETMT-LNHIARRASKTQGVALLTLFSRGFAFVDRLKLLVRRGHLPICWGVLTAALGLSVERSQYLHLFLQARSLLSSSVRLNTIGPYAAQQLLLVRPLVDPAMTWPLGEILAARHDLQHSRIFNS Malgl1 LVLILSDSNPPTGGFIASAGLESYYSHGSFVEHTLANYATSVLPYMCAAHTLL-LNHVSRRASLIQGMALLTLYMRSFALVEQLRLRIRRGHLAICTGVFSCCVGLSVERMIHVNLFLQARNLMSCSIRLNTLGPYLAHQLLALRHVVSACTTWPLGDIVQARHDQLHSRLFNS Mellp23 LINILSDSNLPIGGFVSSSGLESYLAHSEFARLNVVNYASLSIPFMNGVHAMC-LNTVTRRSSLAQGAAMVMLYTKSFSVMDVLKTRVRALHFPIAYALTSGLLGLSCARSIDLHLFLYIRSILSAAVRLNLIGPYLSQRILFIRPMLDATTTWPLGDILSARHDLCHVRLFNS Mnele ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Morel2 LLWQFLDSALPTGGFIASNGLEAFAK--AYVNWSVHSCGYTNLPFVTAVDVFM-NNAIQNAASRKQGDGIVMMGVKCFAILKPFKALLRSGHYPIAFAMIARLLGFDLATTRYLHLHLHARTLLSSAIRLALVGPFQAQHIMT------AAQTFLLGDICSGVHGRLWTRLFNS Mucci2 LLYILTDSALPTGGFVASSGLEASWQAGAWVTTSAHNYASNTNCFVRAGDAVMAANTVARRASLAQGIAMLTLYLKCFTVVKKWKSMIRGGHFAICYGLICRYLKVDLDNTLHLWLYLFTRTIYSSAVRLNVVGPYEAQKLLLSRKPIECCQTNPLLDVCQGMHDRLYSRLF-- Mydma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Neucr2 FLLLLSDSALPLGSFAFSSGLESYLAHNSFLPLSLSSYASTTLPYVLAADATI-VCTVGRRASVAQGRALLSIWDRSLSILKPFSALLRSAHLPPLFGAICALVGLSLEQTAYVYLLSHVKALVSAAVRAGMFGPYQAQKTLAVQEMIGAGQSVPVMDLWIGRHEVLYSRIFNS Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pench1 ALLLLSDSALPLGSFAYSSGLESYLAHNRFLKLSIASIASTSLPYVLAGDAST-PCIVAQRASIAQGRALIGVWERAFRAIDDLSDALKSGHFAPLWGVVCRAMGLDLQQTAYVFVMNHAKAVLSAAVRAGVMGPYQAQNVLALQDTMMAGQVVPALDLWVGRHELLYSRIFNS Phybl2 LLYILTDSALPTGGFVASSGLEATYQAGDFVTTSAHSYAWQTNGFVRAGDAVMVANTVARRASLAQGVAMLTLYLKCFTVVKSWKNKIRAGHFSVCFGLICRYLDVDLENTLHLWLYLFTRSLYSSAVRLNIIGPYEAQRLLLSRGSVECCQTNPLLDVCQGMHDRLYSRLFNS Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 ILLLLSDSNLPTGAFVASNGLESYVKHGSFVRDSLATYARSALPFASDAETMT-LNHVAKRASKSQGVALLNLFSKGFSLVDRLKLMVRKGHLPLCWGVLTGALGLSLERSQYLHLFLHARSLLSASVRLNTLGPYGAQQILLVKPLVQPATTWPLGEILAARHDLQHSRIFNS Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Pucgr2 TLLLLSDSSLPVGGFVSSSGLESFTNHGTFTFSNAQSYANLCAAFFYHIDSMC-LSPVNRRNSYAQGAAFLLLYSKSFGLIDSLKREIRRIHYPISFAFVTGLLQLSFDRAIHLHIFLHIRSILSAAVRLNIIGPYLSQKIMFMKSMLEPATSWPFGEIIQTRHDSCHVRLFNS Punst1 ILLLLADGNLPTGSFVASSGLESYITHGEFVEDSLGTYARTASPFVTDADAMT-LNHVARRASQGQGVALLTLYSKGFSIVDKMKFTIRKGHLPICWGILTAALGLGVERSLRLHLFLHARGLLSAAVRLNAIGPYAAQQLLLIKPLVQPATTWPLGEILATRHDLQHSRVFNS Rhior3 LLYILTDSALPTGGFVSSSGLEASYQAGAFVSSSAHNFASNSNCFVRAGDAVTAANAVAKRASLAQGIAMLTLFLKCFSMVKNWKNRIRAGHFAICFGLICRCLKVDLENTLHLWLYLFTRTIYSSAVRLNIVGPYEAQKLLLSREPIECCQTNPLLDVCQGMHDRLYSRLFNS Rhoto1 LLLVLSDSNLPTGGFVASSGLESWIQHGGFVRHSLHSYARLNVPLLCAAEALT-LNHVARRASIAQGVALLTLYERAFSLVTEYRNKVRKGHMSVAFAVLTAAVGVTLDSALPLFLFLHARSLLSSAVRLNIVGPYLAHRMLLLKPLVDPVTTWPLGEIVASRHDQLFSKVFNS Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 LLLVLADSNLPTGSFVASSGLESYFKHSAFVRDSLASYARTALPFVAGAEATM-LNHVSRRASRAQGVALLTLYAKGLAALDQYKLRVRRGHLPVCWGALTAALGLPLARAVHLHLFLHARGLLSAAVRLNALGPYAAQQLLLVRPLVEPVNTWPLGEILAARHDLQHSRIFNS Schpo1 LSLILSDTAFPLSSFSYSYGLESYLSHQNFLPLSLNSVLHTNLPTVKAAESTQ-TCTIAQKVSTMQGKSLLNIWTKSLSYLDEYERRVRSGHFPVVWGVVCRALGLSLERTCYLFLLGHAKSICSAAVRLDVLTSFQYVSTLATESLLRTAQSWYTLDLWQGRHSLLYSRIFNS Sorma FLLLLSDSALPLGSFAFSSGLESYLAHNSFLPLSLSSYASTTLPYVLAADATI-VCTVGRRASVAQGRALLSIWERSLSILKPFSVLLRSAHLPPLFGAICALVGLSLEQTAYVYLLSHVKALVSAAVRAGMFGPYQAQKTLAAQEMIAAGQSVPVMDLWVGRHEVLYSRIFNS Sphar VLWQLIDSAFPSGGFAHSGGLEAASQYGGAVTTAVQQVASQSLPIMHQVDCSL-TNNVANKASRSQGEALLSSAIDCFPYLSQMKAEGRAFHFAVIFAAVCRELKIPVDDMCDAFLFISLRGLTGAAVRLGLIGPIQAQRLQFLTPATSSASTDPILDLVHSNHDSLFFKLFIS Spipu1 LLWMEV-----IGGFVASAGLEAAVQAGSFVTASLHSYAHSAVPYVRAADGLTGSNHVARRASRTQGAAFLTLLVRGFPVVSVFKTEVRAGHLPICFGVVSNCLGISLERTSHLFLFLHVRAILSAAIRLNLVGPYQGQQLLLLQKSVEAWQTAPVVDILQGLHDRLYSRMFNS Sporo1 LLLLLSDSNLPTGGFVASSGLESFIQHGEFVKMSLHNYSRLNSQFVKQSEEMI-LNRISHRASIAQGNALLSLYSRALALIDKVRSEIRNGHQSTSFGIVMAAVGLSLNRALHLFLFLHARSILSSAVRLNLVGPYSAHRLLLVRQLVDPVTTWPLGEIVASRHDQLFTKVFNS Stehi1 LLLLLSDGNLPTGSFVASSGLESLFAHASSIRDSLSSYARSAIPFVRDTECST-LNHVARRASSTQGVALLTLYSKGFALVDRLKFLVRRGHLPVCWGVLAGALGLSLARTTHLHLFLHARSLLSAAIRMNILGPYASQQILLVRPLVEPANTWPLGEIVAARHDLLHSRIFNS Tapde11 FLLILADSQLPIGSFAYSSGLESCSIHNDFLKHSIDSLCHTTIPFIRAADANT-PCQVARRASLTQGRALLKLIVKTFLQVLAYKAAVHSGHFGVVSGLAGRVLGIGLDRLTFAFLQSHAKAVLSAAVRLSLIGPYESTHLLATRQAIQCGQTFSIVDVWQGRHELLYSRIFSA Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Treme1 LLYILLDSNLPTGGFVSSSGLESYAKH-HFVESEMDNFASTTCPFVCDGESTL-LSVVGRRASKAQGVALLTLFTRSLCVVEEYKRSIRRGHLAVCWGVIMSALGLDLGTSLHLYLFLHCRSVLSSAVRLNLVGPYASTRLLLQGAIDRPSTTWPLGEILLARHDMQHSRIFNS Trire2 FLLLLSDSALPIGSFAFSSGLESFAAHNSFLPLSLSSYASSTLPFVLAADAAV-ICTVGRRASVAQGRALLSIWERSFKVLSNFSALLRRAHLGPLFGVIAAVVGLSLRQTAYVFMLSHVKALVSAAVRANMFGPYQAQKMLAVQALINAGQSVPVMDLWVGRHELLYSRIFNS Umbra1 LLYLLTDSALPTGGFVASSGLEASFQAGDFTLSAAHSFAFNTVPFVRAGEALMIGNTVARRASLAQGVAMLTLHIKCFSVVKQWKKLIRSGHFAVCFGLVCRQLSVSIENTSHLWLYLFTRTLYSSAVRMNIIGPYEAQRMLLAKEGIEACQTNPLLDVCQGMHDRLYTRLFNS Ustma22 LLLLLSDSNLPTGGFVASSGLESFYAHGSFAQSTLHSYARSSFGYIARVHTLL-LNHVARRASKAQGIALLTLYSKAFALVDRMKLDIRRGHLPVCWAVFAACLGVGLKKSVFLHLFLQARSLFSSSIRLNTLGPYLAHQVMRMRPVVQPATTFPLGEIIQARHDQLHSRLFNS Walse1 LKLLLSDSNLPTGGFVASSGLESFVGHGDFLAFSSENTSRTTLPFIKAVEAQM-LNNVNKRASKAQGIAMLTLYTKSFGLIGRFKLLTRKGHLAICWALMTATLGLPLYDSQQLSLFLQARSVLSAAVRLNIVGPYAAQKVLLVRQLVEPATTWPLIELLSSRHDMLHTRIFNS Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3938.fasta_al_trimmed; alignment length = 61] Allma1 ------------------------------------------------------------- Ashgo11 LCRSVACPLLHAEDCPAFHA-GSCP-HLCHRVH-DHLCRPFSFCFRGFLHLKLCPDFYSTG Aspfu1 ICKEFLCDLSHSPVCVHFLR-NRCS-NDCRYSHVAPVCRDFGYCDKGQRHVHECPDYAASG Aurde31 ------------------------------------------------------------- Batde5 LCFSFLCKLSHTPFCVHFER-GRCS-NDCHYLHVAHVCADFGYCEKGQRHIFLCPDYEKNG Botbo1 ------------------------------------------------------------- Botci1 VCKAFLCDLSHTPNCLHFAK-GNCS-NDCRYTHVAMVCRSFGYCDKGERHVHECPDFSNTG Caeel ------------------------------------------------------------- Canalb1 ------------------------------------------------------------- Cangl ------------------------------------------------------------- Capow ICKPFLCLLSHMPVCSFFLQ-GRCS-NACPYSHVAPVCENFGHCPDGKKHTFVCEDFRRTG Catan2 ------------------------------------------------------------- Cioin -----------MPVCSFFLR-GKCA-TDCPYLHVAALCKSFGYCAKAEKHIRACYEFYETG CocheC53 VCKRWFCSLSHAPTCLHFQA-GRCA-NGCRFAHVALNCEAFGYCEKGELHAHECPSFANTG Coere1 LCTKHLCRYSHVPICRHYQN-DNCL-KDCPFSHVAPICRPFGYCAKGHRHVIECPDWVEKG Conco1 ------------------------------------------------------------- Conpu1 ------------------------------------------------------------- Copci ------------------------------------------------------------- Croqu1 ------------------------------------------------------------- CryneH991 ACPNFLCPLSHTPSCTRFQALSYC--TNCPYPHVAPICEDFGWCDTANLHSYDCPEFWSTG Crypa2 ACKEYLCDLSHTPHCVHYAK-GNCS-KDCPYTHRALVCRDFGYCDKGNRHSFECPDFSNDG Debha1 LCRQYLCLLSHTPLCRYFLE-NKCV-NQCTYEHVIWVCRPFGSCSRGFMHLFVCPDFQENG Dekbr2 LCPNIMCHLSHAPSCKFFQE-GKCS-NNCVFSHKTPVCRPFGYCDLGYRHVFDCPDMQEYG Dicdi ------------------------------------------------------------- Dmel ICVSFLCLLSHMPVCRYYLR-GVCV-RDCPYLHKTEICIDFGYCPLAKRHEFSCPELERKG Enthi ------------------------------------------------------------- Falba VCHRFLCRFSHVPHCQKYLR-GRCVDHPCRFVHLAPTCPAFGFCAKGKLHTWDCPDWQKSN Fomme1 ------------------------------------------------------------- Fusgr1 LCKNILCDLSHTPNCLHFAK-GHCA-KDCPYTHSALVCRSFGYCEKGERHVFECPDFSNTG Galma1 ------------------------------------------------------------- Ganpr1 LCTRYLCTFSHAPLCSHFQT-GNCR-RDCLYLHSAPVCSDFGWCDRGERHVYECPSFSATG Gloin1 ICKKWLCYRQHIPHCSHFAK-GMCL-KECRYTHVADYCKEFGFCDAGKKHE-----WANI- Hisca1 ICKEFLCDLSHSPSCLHFLR-GRCS-NSCRYAHVAPVCHDFGYCSKGQRHVHECPDYANTG Klula1 ------------------------------------------------------------- Lacbi2 ------------------------------------------------------------- Lenti61 ------------------------------------------------------------- Malgl1 LCPGVLCLLSHVPHCVHFLRLHSCR-NACAFTHAAPVCRAFGWCDQGHRHAKECPDFTAKG Mellp23 ------------------------------------------------------------- Mnele LCSRFICPYQHMPLCLYFYA-NQCS-KDCPFLHVVPVCEKFGHCDKGKRHTRDCETHFKTG Monbr ------------------------------------------------------------- Morel2 ICKNFLCKLSHVPACVHFQR-AACN-KDCVYPHVAPICRPFGWCEAGDRHVWICPDFGTEA Mucci2 ------------------------------------------------------------- Mydma VCTRFLCIFSHMPVCSYFLL-GQCT-RKCPYRHVAPICEAFGFCPNGKKHTLECEEFLRSG Neucr2 ICKDFLCDLSHTPTCLHFIK-DSCT-KDCKFTHAASVCREFGYCEKGNRHVFECPDFSNTG Orpsp11 ------------------------------------------------------------- Pench1 MCKDFLCDLSHSPTCMHFLR-GRCA-NECRYAHVAPVCRAFGYCEKGEKHVHECPDYANTG Phybl2 ICPRFVCLLSHMPHCLYFQR-GRCK-NSCIFPHVAPVCKLFGYCPKGSKHVHVCPEFAETA Picst3 VCQQNLCLFCHTPVCRYYIE-GKCT-NACKFMHHVWVCRPFGWCSRGFIHLFNCPDFEEDG Plicr1 ------------------------------------------------------------- Polpo VCPKYLCTLQHMPVCYQFLR-GMCT-HNCPYLHVAEVCPDFGYCPNGLRHTYS-------- Pucgr2 ------------------------------------------------------------- Punst1 ------------------------------------------------------------- Rhior3 ------------------------------------------------------------- Rhoto1 ICPLFLCPLSHSPHCLHF---PNCT-RTCPYAHVAPVCRDFGWCEKGKRHVRECWRFAETG Rozal11 ------------------------------------------------------------- Sacce1 ------------------------------------------------------------- Salro VCPRYLCPRQHVPDCVFFSR-GKCD-RNCRYRHVALVCEDFGKCKDANIHEYICPGYFAGG Schco3 ------------------------------------------------------------- Schpo1 ICPKFLCNLSHIPACRYFLL-GKCN-NNCRYVHIAPICFEFGFCELGNQHILQCTDYAMFG Sorma VCKDFLCDLSHIPTCLHFIK-DSCT-KDCKFTHAAPVCREFGYCEKGDRHVFECPDFSNTG Sphar LCRPFVCPLQHMPICTSFFIKGSCD-RKCYDLHQIAVCKKYGYCPNGERHHWICPDFEFRA Spipu1 VCPAFLCKLSHMPTCLHFER-GRCR-NNCPYLHVAAICRDFGFCEAGNRHVYQCPDFAE-G Sporo1 -----------------------CT-RQCPYAHIAKVCRDFGWCEVGKRHVRECWRFSETG Stehi1 ------------------------------------------------------------- Tapde11 ----------H---------------S---------------------------------- Thetr ------------------------------------------------------------- Treme1 -----------------------------------------GWCDKVDLHIWECEEWRKTG Trire2 LCKDFMCDLSHVPNCLHYAK-GQCS-RDCPFTHSAPVCEAFGYCDKGNRHVFECPNFSNTG Umbra1 ICPKYLCLLSHMPHCSHFQR-GKCD-RNCPYPHVAPVCKAFGYCAKGNKHIHVCPDFAETG Ustma22 LCPKVLCPLSHVPHCVHYLRSRNCR-NDCLYTHATNICRDFGWCGRGQRHTYECPEFVEKG Walse1 ICPHFLCPLSHMPNCSHFESPNGCRAGECLFTHVASVCRDFGFCDKGSKHVRECPDYAENG Zygro1 ------------------------------------------------------------- [Cluster3954.fasta_al_trimmed; alignment length = 102] Allma1 QIYIFDNVLSCDALIADAEPAEKNPRKGFAFRDSGRISLLDIADRLALNPHIRLYRYVKGQSFGQHYDESVTAFTLLVYLLAGGETVFYSYSPKKGSVLLHR Ashgo11 KVILVRKFFTCEQLIAHFSVLELFGSRDYAERLNDRASVTDTALKLGLNPQLRLYRYQKGHHFGKHYDESVTQWTVLIYLLEGGDTVFYAVHPMPGLALLHK Aspfu1 QIYLIRNFLPCKTYAFFLAPLTTTPKKGEAVRVNDRFQIQDFAERLGLNANIRVYRYSRGQFFAQHYDDSNTTWTLLVYLCTGGETVFYAVAPEVGMALLHR Aurde31 GLALVPDFFSCTALIALFSGLQPPPAKDEAARTNWRWSGQDFADVLGMNSGIRVYRYAQGQSFGRHYDDSISEWTLLVYLVQGGETVFYRIALRRGLALLHR Batde5 ------------------------------------------------------------------------------------------------------ Botbo1 QIILIDEFLSCKQFSALIEPLQATAKRGEAERVNHRMSVQDFAAMMSLNSNIRLYRYHPGQYFGPHYDDSVSEWTLLLYIVVGGQTVFHVPSLNRGTALLHR Botci1 QIITIPNFWTCKNYVSFLKPLTTTPKKGDALRVNDRFRIDDFAERLGLNPAIRIYRYSKGQFFDCHYDESNTTWTLLLYLCLGGETVFYVIGLETGMVLLHK Caeel ------------------------------------------------------------------------------------------------------ Canalb1 QIIIIKNFFNCNELIKSFENMETTKSKEYAARFNDRSSMNDSANILGLNPQLRVYRYTRGHHFGKHYDDSVTKWTLLIYLFKGGGTIFYNIHPNKGMALLHK Cangl ------------------------------------------------------------------------------------------------------ Capow ------------------------------------------------------------------------------------------------------ Catan2 QLFVIEHALPCTALIDAAEPAEKNPKKGFAFRDSGRIALPGLTKRLALYNLIRLYKYERGQSFGCHYDDSVTEYTLLVYLLAGGETVFYSVAPIQGRALLHR Cioin ------------------------------------------------------------------------------------------------------ CocheC53 QIITIPNFWPCKTYVSFLSPLTTTPKKGDAVRVNDRFQIDDFAEKLGLNPNIRIYRYTKGQFFDQHYDDANTTWTLLLYLCIGGETVFYQVDLQVGLALLHR Coere1 HIFLVRGFLDCEGFIKIADP----PKRGEAFRNNARWSITDCAQSLGLFENIRLYRYGPGERFGKHYDDYFSEYTLLVYLPSGGETVFYSVKPEAGLALLHK Conco1 ------------------------------------------------------------------------------------------------------ Conpu1 QILVLDDLMSCKLFVKFIDPLELTKKKGEAERVNYRFSTTSFAERLSCNSNIRMYKYTPSQHFGPHYDDAISEWTLLIYLVEGGETIFYTPPLRRGTALLHR Copci QILVVDDFLSCKEYVKFIDPLELTKKRGEAERVNHRFSVTSFAQKLSFNSNIRVYKYTAGQYFGPHYDDSVSEWTLLVYLVEGGETLFYTPPLKRGSALLHR Croqu1 ------------------------------------------------------------------------------------------------------ CryneH991 QIYTVDDFFSLRAVLAWAQSLELEPGKGEAERTGRRASLHSIASSLGLSPNIRVYHYPPHTFFGQHYDMPQSCWTVLVYLVTGGGTTFYTVEPKAGRMLLHW Crypa2 RVLLVRNFWPCRDYVSFLRSLTTTPKRGEAARVNDRFQVLDFAKRLGLSPNIRVYRYSPGQFFDAHYDDSNTTWTLLLYLCQGGETVFFAVPPETGMLLLHK Debha1 QIIIVEKFFSCNELIKSFEKMETTKSKDYAARFNDRGFSVDASRNLALNSQLRIYRYRKGHHFGQHYDESVTKWTLLIYLFKGGGTIFYNVHPSKGMALLHK Dekbr2 ------------------------------------------------------------------------------------------------------ Dicdi ------------------------------------------------------------------------------------------------------ Dmel ------------------------------------------------------------------------------------------------------ Enthi ------------------------------------------------------------------------------------------------------ Falba ------------------------------------------------------------------------------------------------------ Fomme1 KILLIQDAFDCKQFIKFMEPLELTPKKGEAVRVNYRINIQSFAEALSFNSNIRMYKYTEGQHFGSHYDDSVSEWTLLIYLVVGGETIFYVPELRRGMALLHR Fusgr1 KVVLIPSFFPCRDYVAFLKPLQTTPKRGEAVRVNDRFQVDSFATRLGLSPNIRIYRYSKGQFFDCHYDDSNTTWTLLLYLCVGGETVFYAVPLDTGMLLLHK Galma1 QIIVIDDFFSCKTFAKFIDPLELTKKRGEAERVNQRFSVTSFAQKLFCNSNIRVYKYAPSQFFGPHYDDSVSEWTLLIYLVEGGETLFYTPPLKRGTALLHR Ganpr1 ------------------------------------------------------------------------------------------------------ Gloin1 QIVIIPSFFTCANMINFINSLESAPKKGEAYRDNDRFSIEDFSQELGLNPNIRIYKYSKGQKFGQHYDDSVSEWTLLIYLLYGGETVFYVIKPERGMALLHK Hisca1 QIPIIRNLFTCKTYVSFLSPLVTTPKKDEAVRVNDRFQMHDF--------------------------------------C--GSGVF------IGV----- Klula1 KVILINKFFDCDVLIRHISVMESFGTKDFAARANDRFSITDIASIIGLNPQLRVYRYEKGHHFGRHYDESVTQWTLLIYLLIGGDTIFYNVHPSKGLALLHK Lacbi2 ------------------------------------------------------------------------------------------------------ Lenti61 QILLIDEFFSCKKYVKFIDPLELTKKRGEADRVNHRMSISSFAQRLSLNSNIRVYKYTPGQHFGPHYDDSVSEWTLLIYLVEGGETIFYVPPLTRGTALLHR Malgl1 ------------------------------------------------------------------------------------------------------ Mellp23 ------------------------------------------------------------------------------------------------------ Mnele ------------------------------------------------------------------------------------------------------ Monbr ------------------------------------------------------------------------------------------------------ Morel2 QVLVFPNFLSTRALTDYLLKLDPTPRPGYAFRDNDRIQFDSFASMVGLSRNIRMYRYQQGQSFGAHYDESVSEYTVLIYLLKGGETVFYAVKPERGLLLVHK Mucci2 QIYVIPKFLNCDQLVQYFEPIASAPRRGYAFRNNDRQSIQDVASTLGLNSNIRIYRYRKGHSFGAHYDESVTDWTLLIYLMKGGETVFYVVQPKKGMALLHR Mydma ------------------------------------------------------------------------------------------------------ Neucr2 KVVVLRNFFPCRDYVSFLSPLITTPKRGMAVRVNDRFQIDDFADRLGLNPNIRIYRYTKGQFFDAHYDDSNTTWTLLLYLCIGGETVFYAVAPETGMLLLHK Orpsp11 ------------------------------------------------------------------------------------------------------ Pench1 QIYLIRNFLSCKTYASFLAPLTTTPKKDEALRVNDRFQIDDFAEMLGLNPNIRIYRYSAGQFFGQHYDEANTTWTLLVYLCTGGETIFYAVAPEVGMALLHR Phybl2 QIYLIHDFFTCNSLIQHFEPLQQVPRPGEAFRSNDRQSFEDFAQRLGLNSNLRIYRYRPGQMFQAHYDESVTEWTLLIYLMEGGETVFYVVQPQQGMALLHA Picst3 QIVVIEKFFACNELIRSFETLETTKSKEYAVRFNDRCSLTDSAEILGLNPQLRIYRYRSGHHFNPHYDESVTKWTLLIYLFKGGGTIFHNIHPGKGMALLHK Plicr1 QILLLDDVLTCKIFVKFIEPLELTKKRGEADRVNHRYSITSFADKLSFNSNIRLYKYTPSQHFGPHYDDAVSEWTLLIYLVEGGETLFYTAPLARGMALLHR Polpo ------------------------------------------------------------------------------------------------------ Pucgr2 QIMTMRELLTCKRVIRALDRFETTPKRGEAFRYNDRISIHDFADTLGLNPNLRFYRYRVGHKFEKHFDESVTEHTLLIYLLRGGETVFYSVSPVAGLALIHR Punst1 QIILLDGLFDCKRYVKFIDPLELTPKRGEAERVNHRISASSFAEKLSLNSNIRMYKYTPEQYFGPHYDDSVSEWTLLIYLVEGGETLFYTPPLRRGMALLHR Rhior3 QIYVIPNFLNCQAVITYFAPKINTPKRGEAFRNNDRQSMDDVASALGLNSNIRIYRYRKGHSFGAHYDESVTEWTLLIYLMQGGETVFYVVKPARGMALLHR Rhoto1 GIILVEDFFPRKAFLSFLTPLRLNPKRGEAERTNARTSVQDFAKRLGLNPNIRVYRYGEGDFFGPHYDDDISEWTLLIYLVVGGETAFYVPELRAGRALLHR Rozal11 ------------------------------------------------------------------------------------------------------ Sacce1 ------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------ Schco3 QIILIKNFLSCKAYAHFIDPLELTKKRGEASRVNYRYSITSFAKRLSMNSNIRMYKYTQGQYFGQHYDDSVSEWTLLVYIVQGGETIFQVPPLSRGMALLHR Schpo1 ------------------------------------------------------------------------------------------------------ Sorma KVVVLRNFFPCRDYVSFLSPLITTPKRGMAVRVNDRFQIDDFADRLGLNPNIRIYRYTKGQFFDAHYDDSNTTWTLLLYLCTGGETVFYAVAPETGMLLLHK Sphar TIYTLTNFLSCAAWIEFGEGFEASQNRECAHRDNGRISIESIAQAFSCNTNIRLYKYGPGQRFGRHVDESVSVYTVLVYLLVGGETKFYAVRPKKGQALLHG Spipu1 WIFLIPSLLTCSQLLAACTPLQLSQTRSVAFRDNDRSAFTSLSHLIGLNNMWRLYRYREGQRFGPHYDEEAGYFTLLIYLLEGGETVFYSVAPVTGMALLHA Sporo1 GIVVVDQFFSLTAFLAFLQAISWTPKKGEATRTNYRFQIQDFARQLGLNGNIRCYRYEKGSYFGPHYDDDFSEWTLLVYLVVGGETAFYVPELKAGRALLHR Stehi1 ------------------------------------------------------------------------------------------------------ Tapde11 QICLIDAFLTRQHLLSLFEPLLSRPRRGEATRTNGRFAVHDFAESLGLNPNIRIYRYPVGTFFGPHFDDSVSEWTLLVYLLQGGETAFQAPAPRHGLALIHR Thetr ------------------------------------------------------------------------------------------------------ Treme1 QIYIVDDILTLLGLMEWTKSMEMEAGKGEAERTSRRSAVHSIASKLQLSPNIRLYHYPPKTYFRPHYDTPQSSWTILIYLI-GGSTVFHLVEAKAGRVCFHW Trire2 NIVLLSSFFPCRDYVAFLKPLQTTPKKGEAVRVNDRFQIDDFARRLGLNPNIRIYRYSKGQYFDCHYDDSNTTWTLLLYLCVGGETVFYVISLETGMLLLHK Umbra1 QIYTISDFFSCDSLISYIEHLQTTPKRGEALRSNDRISLSDFADTLGLNSNIRIYRYTPGQKFECHYDDTVSEWTLLIYLMAGGETVFYVVRPMKGTALLHR Ustma22 ------------------------------------------------------------------------------------------------------ Walse1 ------------------------------------------------------------------------------------------------------ Zygro1 ------------------------------------------------------------------------------------------------------ [Cluster3960.fasta_al_trimmed; alignment length = 145] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 SLLTL--AVVSFFVIRW-FLKRDPAQVEQIAQMFPQLSTREIMWDLQRNGGNVAATTERIL-SGRGLDMPPPSFTTTAP----TAAMSGAS-DLIARYNLSSKINAWSQSKEERQRLLQKRRDDMILAARRRMEQK----QRQAD Aurde31 NVLVA--FAFIYLLVRWL--SKTEDMIMTVHAAFPDIPRANIHYDLLKTG-NAQVTSNKILERGV-LDAPPASY-----QTAQPAASSSPA-DLISRFHLEERVAKWETSAEKREASLRERKAQMILEARRRMAEKLQAS----- Batde5 TILVS--LVLLFFVVRYVLFGGPLSSVDAVFSMFPHIPRATIELDLSNTG-SVEETCDRIL-SGA-LVAP---------VTPVPV-SLPVF-PY-----LKSELEVWEPSPDARQLSLRQRKEFMVQQARRKFLETQ-------- Botbo1 NFAVA--IAVMYGVYRWW--SSTHDMVNMVSSAFPQEPKENIHYDLLKTG-SVERTINNLLEKGY-LERPSAAY-GYAPTVATPAVQTTKA-NLIARYNLQERVSTWEDTAEKREASLKERKAQMVLAARQRLAAQKLKAA---- Botci1 QLLII--ILVGAFAVRYLFFSGREADVERIQQMFPQVPRRSIMWDLQRNGGNVVATTERIL-SGRGLEVPPQSFPAAASSTSIQ-----SS-DLITRYNLKAKLAEWSSNKNERQALLQKRREEMILAARRKMEARVAKE-EQGG Caeel ------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 QVLVF--IVVTFLAVRW-YFSKNLAQIDQVAEMLPQLNRRDIAWDLQRNGGNVAATTERAL-SGRGLDTAPPSFASPAPARPAA-----PA-DLITRYNLSSKINEWSADKNERQANLQRRREEMILAARRKLEAQ---EAKASG Coere1 VFFIV--LGVVFMVLRWL-LG-RREHVEAIQAMFPDIPETAIRADLGRTG-SPAITTDNILRNGGTLPLPPVAGSSQAASDFPRSHGVILN-PLVNRLRVATKGDTWETDSDKREDILRKRKEFMLMEARKKYLEKQSSSSKGPA Conco1 KILIT--VVGLFLVFRWV-LG-TPDMVEAVKAMFPHIHTAAIQADLALTG-SVEATADKILRLGN-LPMPA---ATANANNNNTEPNNSGA-NLAQKFNVDEKEEIWSAESTERQDALFKRKQFMIQQARQRMLSKQNSESEAS- Conpu1 NVVVA--FAVLVFVFKWA--TSTQQMVDQVHSMFPDIPPDNIRYDLLRTG-SIEVTTNKILERGY-LEAPPAAY-TPAAPAAPASASSSVL-SLISRYNLQSRVDSWQDTAQKREATLQERKAQMILAARQRMLAQQKAA----- Copci NILVA--FAVIIFLFRWV--TSSQDMISTVSNMFPDIPIANIHYDLLRTG-NVEQTTNKVLERGF-LEAPPAAFTNTSSTRAPAAA-SKPA-SLIERYQLEERIKKWEDSPEKREASLRERKAQMILAARQRMLAQQVQS----- Croqu1 SVLAA--IGIIALVYRWF-TTSSQTQVERLRTTFPQLTEHEIRYALVTTAGGVEAVAERVLVHGG-LPPPPPNFATPVSNTSSSGTGSKST-TLISRLCLGKRQQDAGASPDQSSGVLRDRKAKMVLESRWRLLQKERKG----- CryneH991 ATIIL--ISAVYFFVKWLIGTKTPSMVETVHSAFPHVPVPNIVYHLSRTR-SAQATSEEILERGV-LPPPPPTF-QP---APTPFS---AS-SLIDRYNLSSHKGKWEESKEKRELGLKERKERMILEARKRMLEKQAKE----- Crypa2 SLVVI--IVLGGLL--YKWLSSREVAVERIQQMFPQYDRRTILWDLQRNGGSIAATTEKIL-SGR-IETPPITFGSNMGSSTSTTQRQTAE-NLIQRYNLQDKI--WSTNKDERQSLLQKRRDEMILAARRKMEAKLAAE-SAAG Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------- Dmel ------------------------------------------------------------------------------------------------------------------------------------------------- Enthi ------------------------------------------------------------------------------------------------------------------------------------------------- Falba ------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 NVVVA--LAVIVFVVRWA--TSTPEMTETISSMFPDMPRENIHYDLLRTG-SVEMTTNKIIERGF-LDPPPQAYQRPASRAQTPNTSSAPA-SLIARYHLEERTKEWEETPEKREASLRERKAQMILAARKRLIEQQKAAAGPSG Fusgr1 YLLAI--LAISGLVIRYMFFSAREIAVERIQQMFPQADRRSILWDLQRNGGNIQTTTERIL-SGR-LDTPPVTFGQAATSGSAT--RQ-PE-DLITRYNLKNKL--WSSNKDERQASLQRRRDEMILAARRKMEAKLAAE-AAQG Galma1 NVLVA--FAVIVFLFRWA--TSTQEMVDTISHMFPDIPADNIRYDLLRTG-NVELTTNKILERGY-LDAPPAAY-VSAAALAGAAG-TPAK-TLISRYGLNDRAQKWEDSAEKREASLKERKAKMILAARQRFLAQQKAT----- Ganpr1 IFSVAFLLIALVAAYKLI-FSGPRAKIDAVASMFPDLARDAIEYDLARSG-SVERTVDNII-NGR-LQSPPPT-SSSSSSSSGPSRELDAI-PRV-----------WTDTPESRAKNLRDRKLLMIEQARRKFAQKSAES----- Gloin1 SLLFA--ICLI----VWI-IKKTPEMVETVCSMFPNIPPAAVQYDLQKTG-SVEVTCDNVLQNGG-LPLP----VASFTIPSTTQAGISTS-SLIEKYKLQDAVKRWEATAEKRQELLQWKKDAMVLQARERYLEKQKKKAKTKN Hisca1 SLITL--AVFSFFVIRW-FLGRDPAHVEQLSQMFPQLDRRDLMWDLQRNGGNMAATTERVL-SGRGLDTPPPSFT------AETQAPAS---DLISRYNLADRIQSWSQNRAERQRHLQKRRDEMILAARRRLMEK----DRAAE Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 NVLVA--FAVIVFLFRWV--TSTQDMINTISNMFPDIPTDNVRYDLLRTG-SVELTTNKILERGF-LDAPPPAY-TSSSTTHRSSNPTPKA-TLITRYHLEDRVLNWEESSEKREASLRERKAQMILAARQRMLAQQEAK----- Lenti61 NVLVA--VAVIVLVVRWA--SSTPEMVETVHSMFPDIPSDNIRYDLLRTG-NVQQTSNKILERGF-LPAPPPAY-EPAAPAQPPAA-SSKA-NLISRYHLEGKTSIWEDTAEKREASLRERKARMVLAARERLLAQQAKE----- Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 SVLAA--IGIIALVYRWF-TTSSQSQVDRLLTTFPQLTENEIRYALVTTTGGVEAVAERVLIQGG-LPPPPANFATSNSNTSSSTGGSPSS-SLISRLCLEKRDQDSSGSTDQNSNALKDRKAKMVLESRWRMLQKDRKG----- Mnele ------------------------------------------------------------------------------------------------------------------------------------------------- Monbr ------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 SLTIV--IVIIFMVFRW--LS-NPEMVETVRAMFPHIPTAAIHYDLQKTG-SVEQTCDNILRDGT-LPMP----TPPTAATSSAAPGSSSGGNLVQRFKLQEAAEKWAESAEKRQEVFKSRKEFMVLQARKRFLEEEARKAKAKE Mucci2 SILVA--VFLILIALRWM-LG-TPQMIEMVRAMFPDIPTAAILADLQRTG-SVETTVDNALRDGG-LPLPS---GSPNSNATNNSS--RKS-NLVQRYKIDVQQDTWEASPDKRQEMLRKRKEFMVLQARKKLMEQQQKKMEHQG Mydma ------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 SLVIV--LLVTGLAVRYFFFSGREAAVETIQQMFPQVDRRTILWDLQRHGGNLQATTERIL-AGR-TETPPITFSSPETTAAAQQSSKYAE-DLITRYNLRDKLASWSSNREERQSLLRKRRDQMIIEARRKMEAKIAAESAAAG Orpsp11 ------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 SLLTL--AVVSYFVIRW-FFNRDPAQVEQIAQMFPQLSTRDIMWDLQRNGGSVAATTERIL-TGRGLETPPPSFTNIPPTQTATAA------DLISRYNLSAK--AWSQNKEERQRILQKRRDDMILAARRKMMQK------NLG Phybl2 --------------MRWM-LG-TPQMVEMVLAMFPDIPQPAIIADLQRTG-AVETTVDNALRNGG-LPMP----STPPSGSSSSSN--RKS-NLIQRYNLDSKNTEWEASADKRQEMLRKRKEFMVLQARKKLAEEQKRKAE--- Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 NVVVA--FAVIVFLFRWV--TSTQEQVETVHSMFPDIPIDNIRFDLLRSG-NVEHTTNKILERGF-LDAPPAGYQSSAAPVARPVA----K-NLIARYKLQDRIAAWEDSAEKREKSLQERKAQMIIAARQRFLAQQAKASN--G Polpo ------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 NVIFA--LAAIFFAFRWL--TSTDEMAHRVADIYPDIPRDNIRYDLLRTG-DVAVTSEKILTKGY-LDAPPSAYESSSAPHAQPSS---PA-SLISRYHLEDRLASWEDTPEKREASLRERKAQMILAARQ-------------- Rhior3 ---------------MW--LG-TPQMIETVRAMFPDIPIAAIQADLQRTG-SVETTVDNALRDGG-LPLP----PSTNTAASNNSNSARKT-NLVQRYKIDVDHSEWESNPDKRQEMLRKRKEFMVLQARK-------------- Rhoto1 GWAVA--AGLCYAAYKLV-FGSPQASIDQITSMFPHVSQAAARWELERNGGSVERAVERALREGG-LPQPPAS---ASTSTPRPATSTSSA-SLIARMGLQNKVVSWSPNAAEREKNLRARKEKLVLEARRKLLEKEQRRRQAQG Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------- Salro ------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 NVLVA--FAVIVVIFRWA--TSTQGMVDQVLAMFPDMPPDNVRFDLLRTG-SVQLTTNKILERGF-LDPPPQAY-QPAAPSSTTAA---AA-NLIARYHLEERLKRWEESAEKREASLRERKAQMILAARQRLLAAQKGKA---- Schpo1 GCAVV--LTVTVLTLRWM-FRVNSEHVHLVKTVFPHLESSAIAYDLQKTK-NVDATIENAL-RGQPLPLPPRNSASSHSEETTPSHSSASS-SLIETYNLSSRISSLPSSKKEREELFRKRKEEMILAARKRMEGKIKGE----- Sorma SLVIV--LLITGLAVRYFFFSGREAAVETIQQMFPQVDRRTILWDLQRHGGNLQATTERIL-AGR-TETPPITFTSPETTAAAQQSNKPAE-DLITRYNLKDKLASWSSNREERQSLLQKRRDQMIIEARRKMEAKIAAEAAAAG Sphar ------------------------------------------------------------------------------------------------------------------------------------------------- Spipu1 VISVA--LIILFFRY-IV-FGGSPDKVDTVLSMFPAFPRSTIEADLARTG-SVEQTCENIL-TGV-LVPPPQP-GSSSSST-----PLSE--PRM-----------WEQTAEAREKSLRARKEYMLRQARQKMLEKQQRSE---- Sporo1 GWAVA--AGLCYTAYTLI-FGSDQTKIDRVSEMFPHLSQRSIRWELDRNGHSVERTIERALREGG-LPEPPAS-TSSNTGTQTPPTSSSST-SLIKRLGLNNKLGSWANSREEREERLKKRKENLVLEARRYI-------ATPFA Stehi1 NAIVA--FAVIIFIFRWV--TSSDEMTNQICGMFPDIPRENVHYDLLRTG-SVERTTEKILERGF-LDAPPPAY-APTAPQARPGASSASA-TLISRFKLEELEKQWEDTAEKRERSLRERKERMILAARQRMLEKQQQQ----- Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 SSLFV--VALLAILIRWW--SKTPAMVESVHSTFPHIQKKDIIWSLSKTG-SAQATSEEILEKGF-LPSAPASF-NPVHVAPQKIS------SLIEKYGLASRKGKWEDTREKRERELRERKERMILEARRRLLESQSRQ----- Trire2 FFAIV--LLVSGLIVRYLFFSGREVAVQRIQQMFPQVERRSILWDLQRNGGNIQSTTERIL-AGR-LETPPITFTQSPPSGSSG--KQ-PE-DLITRYNLKSKVTEWSSNREERQAALQRRRDEMILAARRKMEAKLAAE-AAQG Umbra1 --------------------------------------------------------------------MPA---SPPTASGNSRNISAASG-NLLQRYNLESKLSSWETDAQKRQEMLRKRKEHMILQARRKMMESQQQAAEGSG Ustma22 GALLA--IVVLWSILRFA-FGGPQHMVDSIKALFPHIPDASIRYDLQRSG-SVEETCERILNEGG-LPSPPAG-STAETSTSPNAASATSA-NLISRFGLQSRLTSWATTPEERARILKDRKEKMILEARRKMLERQKANTTPAA Walse1 SILIA--VGAIYGFYRWF--SSRQADVQALRTLFPQIDNASLVYDLVQTR-SIERTAENVLRRGR-LAQPPSGF-LPSHLDVEPLT-RAAT-NLIEKYHLK-----WGNTTTEREKAFKDRKAKMILEARKKLIDKKKSE----- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3964.fasta_al_trimmed; alignment length = 68] Allma1 ALLWDACLEILKVVRDRPEIILFGTGKLQALLKELCISYEVQNTRNACSTFNVLADEGRNVAAC-LLP Ashgo11 -------------------------------------------------------------------- Aspfu1 -------------------------------------------------------------------- Aurde31 VFLWDDLFAPFEVVVPKPELVIVGTGAVRTALNEMGLALDIMDTRNACSTFNLLLEEGRRVAAA-LVP Batde5 -------------------------------------------------------------------- Botbo1 VFLWDERYKIFEVVVPKPEILLLGTGRLRAYLNHIGIQIDIMDTRNACSTYNLLAEEGRRVAAA-LLP Botci1 -------------------------------------------------------------------- Caeel -------------------------------------------------------------------- Canalb1 -------------------------------------------------------------------- Cangl -------------------------------------------------------------------- Capow PLLWNESLTLFHLVNPKIELLLIGTGSVRQMLKEKRISLEVLDTPHAATTFNFLSQEGRLVAAA-LIP Catan2 AVLWDDTVRVFELMKNKPEIVVFGTGRLRQVFTSNGMQVEVASTRNACSTFNVLVAEGRHVAAC-LLP Cioin -------------------------------------------------------------------- CocheC53 -------------------------------------------------------------------- Coere1 -----DALAILSIVTPKPELVVVGGGAAREYLTSIGLNVELANSKNASSTYNTLSEEGR--NAA-LLA Conco1 PYQWNDSLRSLELVRPKPDLLIFGTGLLIKYLTNLGIQIEVMDTRNACSTFNLLIEEGRLVAGAFFLP Conpu1 VWLWDDCFKLFEVVVPRPEILIVGTGELRKYLNGLGIQVDAMDTRNACSTYNLLAEEGRHVAAA-VLP Copci VFLWDEHFELFDTVVPAPEILLFGTGKLRTYLNQKGVQLDIVDTRNACSTYNLLSEEGRRVAAA-LLP Croqu1 PLLWKDSLQLFQIIHPRPDLLIIGTGSIRTWVHSLGIQLSVLDSRNAASTYNLLVDEGRSVAVA-LQA CryneH991 VLLWDERFGALEMLVPRPEILLLGTGQLREYISGLGIQLDVMDSRNAASTYNLLVEEGRRVAAA-LCP Crypa2 -------------------------------------------------------------------- Debha1 -------------------------------------------------------------------- Dekbr2 IFEVNKFLDLLRALYPKPELIVLGLGKTREGFNKLGIRLEISDTEHAAMNYDMLATE-RTPAGALLLP Dicdi LFLWDDTLATLDIVEPPTEFLLIGTGAIKDISTRYKVNVETMTTINAIGTYNILAEEERRVSAF-ILP Dmel -------------------------------------------------------------------- Enthi -------------------------------------------------------------------- Falba -------------------------------------------------------------------- Fomme1 VFLWNEQFEMFEVVVPKPEILILGTGKIRMYLNSIGIQLDVMDTWNACTTYNLLAEEGRHVAAA-LLP Fusgr1 -------------------------------------------------------------------- Galma1 VFLWDDNFQLLDMVTPRPEILLLGTGKLRPYLSKLGIQLDVMDTRNACSTYNILSEEGRRVAAA-LLP Ganpr1 VLLWDDAFKVFEVLEHTPEILVFGTGALRRYLHSLGIQCEVQKTRTASSTYNVLLSEGRVVAAA-LLP Gloin1 LIMWDDFLKVFEVIKPRPELLIFGTGKIRQYLNGLGIQIEIVDTRNALATFNVLAEEGRNVATA-LLP Hisca1 -------------------------------------------------------------------- Klula1 -------------------------------------------------------------------- Lacbi2 VYLWDDHFELFDVVVPKPEILLLGTGKMRTYLNDRGIQLDVMDTVQK-RVRDVQPSSGRR-------P Lenti61 VFLWNEHFEIFETVVPKPEILLLGTGELRQYLNKAGIQVDVMNTRNACSTYNLLEEEGRRVAAA-LLP Malgl1 -----DVWTIFDITSPKP-------GNIRARLHSMGIQLDVQNTRQACSTFNLLVEEGRNVAAA-LLP Mellp23 PLIWKDSLEIFKFLFPRP-----GTGEIREWIHSLGIQLTVLDTRNAASTYNLLIDEGRSVGVA-LQA Mnele -------------------------------------------------------------------- Monbr -------------------------------------------------------------------- Morel2 VFLWDEIFKVFELMNPRPEILIVGTGKVRAVVRSLGLQVDMMSTANAAATYNMLAEEGREVAAA-LLP Mucci2 PFLWNEAFKIFELVSPRPELIMFGTGRIRQYFFKLGIQVDQMNSKHAAATYNVLAEEGRRIAAA-LLP Mydma YLSWKESLQLFTVIEPKIEILVIGTGEVQMYFKKFNISYEVSDTPNACATYNFLLEEGRLTGAV-LIP Neucr2 -------------------------------------------------------------------- Orpsp11 -------------------------------------------------------------------- Pench1 -------------------------------------------------------------------- Phybl2 AFLWRDVFKIFEVVTPKPELIMFGTGKVRQYFYKLGIQVDVMNTKNAAATYNVLAEEGRRVAAA-LLP Picst3 -------------------------------------------------------------------- Plicr1 VFLWDEHFEIFETVVPKPELLLFGTGKLRLHLNKIGIQTEISDTRNACSTYNLLAEEGRRVAAA-LLP Polpo CLLWDESMAALAIVDPPIEFVIVGTGELDQLKRRYHINIEVMSTVNALGTYNILAEEGRRVAAF-LIC Pucgr2 GMLWNSQFKLFEIIHPRPEMVILGAGKIKSYLNSIGIQLDVLDTRNGCSNYNLLVEEGRSVALT-LEP Punst1 VLLWDERFEVFDIVVPKPEILLIGTGKIRQYLNEIGIQIDVMDTWNACSTYNLLAEEGRRVAAA-LLP Rhior3 AFLWNDAFKIFDIVSPRPELVLFGTGKIRKYFFKKGMQVDQMNTKHAAATYNVLAEEGRRVALA-LLP Rhoto1 CFMWDEKLRLFEVLNPRPEILLIGTGSVKRYLNGLGIQVDVLDSRNACSTYNLLQEEGRRVAAA-IYP Rozal11 -------------------------------------------------------------------- Sacce1 -------------------------------------------------------------------- Salro -------------------------------------------------------------------- Schco3 VFLWDKHFEVFETVLPRPEILLLGTGKIRNYLKSLGIQLEVTSTRDACSTYNLLTEEGRRVAAA-LLP Schpo1 -------------------------------------------------------------------- Sorma -------------------------------------------------------------------- Sphar -------------------------------------------------------------------- Spipu1 VFMWDDHFKLFEVTQPVPELLVIGTGALRSYLHKLGLQLEVMASRQAASTYNILLQEGRRPAAA-FLP Sporo1 AFMWDEKLRVFEVINPRPEILLVGTGKFKQYLNKLGIQVDVLDSRNAASTYNLLSEEGRRVAAA-LYP Stehi1 VFLWDERFELFEVVVPKPEILVIGTGKLRRYLSELGIQVDVMDTWNACTTYNLLAEEGRRVAAA-LFP Tapde11 -------------------------------------------------------------------- Thetr ALLWDDALILPRILHPRMDLLLIGTGKLLDPLRARGIAVEAMDSINAAATFNFLAEEGRAVGAA-LMP Treme1 -----ERFAIFESVSPRP-------GQIKEYVSSLGVQMDVMDSRNAASTYNLLIEEGRRIAVA-LCP Trire2 -------------------------------------------------------------------- Umbra1 AFMWNEMLKIFEVTAPKPELILFGTGKLRTYLFKLGIQVDQMSTKNAASTYNVLAEEGRRIAAA-MLP Ustma22 VFLWDEVFAIFQIVDQRPEILLFGTGKIRQYINELGIQLDVQSTHDAASTFNMLSEEGRKVAAV-LIP Walse1 VFLWKDAFKVFETLTPRPEILLLGTGKFNKYLNSLGIQVDVIDTKNACSTYNILVEEDRNVAAA-IFP Zygro1 -------------------------------------------------------------------- [Cluster3973.fasta_al_trimmed; alignment length = 174] Allma1 EFGVDFAS--WETGFRGLKFVPPG-LHFIRTGFFILVCEWDAKNEDDPFLGTYPRQSKNITAQLDLILIHFTDFDLKDPSRVGITRYSMDKSW-LLKSVMLLGELQLAFLCLLVGQNFEGFEQWKKLMHLICRSVEAIDQFFVKFMAVLRDQLARDFFVDVVSQDAQKRFEVEL Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Aspfu1 LVGIDLVT--FTSTFHGIRDLPNG-WHFLRSGGWIFVWKWNSETESRGGLFRYRDLTNNISRLLSRIVFSFLPVDLKREGAIGRTEAAQDRSW-ALGDLIILGELQFTFLMVMTLMNYSCLQQWKRLLELVLTCQNAIKDFMVSVLRLLLLQLKDDVEGGLFDIDVKDEYDWEL Aurde31 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Batde5 ELGIDYNV--WETGFKGLSGVPCG-MHFIRSGFFIHVWHWCPKTETLPHMGPYPRLSSYISQLVARTLIHFVPITLKPPGSTGVTKYSLDKSY-LLETLILLGEFQLAFVIFLLGQVYDGFDQWKALVQLVCLSCESIATFFVKFIDLLRIQLEQDFFYDALASGMKTRFNWDV Botbo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Caeel EFGIDYKS--WKTGFMGLKMIPPG-VHFVRIGFFILVKKWNTESETDSSLAPYPGLTDFITDTVERIHIRFQDIP-PSQNRVGYS----DRLYRLLRALGLLAEMQIAFVCFLQGQVFEGFEQWKRIIHLMSCCPNSLGSLFMSFIRVLFFQLKTDFFVDIVSRDLTNQFKWDF Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Capow MLHMDLQP--FHVAFRGFKLIPPG-LHLVRTGFFTVVKHYNPATESDKFMAVYPNLVPHVQSTVTRVLFRFAKIA-KPPNATPRTRYSLDTSY-QLRQTVFLGEWELGFVMFVLGQQLEGFEAWKASLRIISHAEEQLPLFFTPMFGTLLAQLQENFFQDALSQHCRKTFEWQL Catan2 EFGIDFAE--WAIGFMGIKFIPPG-LHFFRNGFFTIVFEWNPSSEEDRNLGTYPRLTRHITNLLHRILIQFTSFDLKDPALHGVTKHSLDKSW-LLLQTVFLGELQLAFICLLVGHNYEGFEQWKRIMHLVCQSRDAVGSLFADVLDVVHDQLAKDFFIDLLSSGCRKRFGMEL Cioin EFGMDWNS--WSIGFEGVKMVPPG-IHYVRTGFFIVVKRWLPESEEDKNLAPYPSMSNHCTHLVDKLSIRFSKIP-EPEGAEAITKHSMDSSY-VMKAIILLGELQFSFLCFILGQVMDAFDHWKKLVRIICYCENSLHDFYLLLISVLYHQIVSDFFVDITSSDLTKKLKWKF CocheC53 LAGIDLLS--FTSSFRGVRNVPHG-LHFVRHGAWVFVKKWDQSTEDD-GLTPYRKLTTHITTILSRICLRFLPIDLKREGATGRTEAAQDRSW-FLGDLIILGELQFAFLMVLTLNNNSCLEQWKRLLRLLLTCRQAVKELFLDLFKCLRIQLGVDAEGDLFDMNMEREFGWQP Coere1 EFGIDLDT--WETGFKGLKMIPPG-IHYIRSGFFVVVRKWSKENEEDTGLGAYQLLTEHITKLLHRILFHFTHINIRPKDAKPIRLFSQDKSW-LLRHILLLGEFELSFLVILVGQNFTGIEHWKRILHLVLGSIQILEDLFVPILRILLCQLGHEFVASVLEQDLLAGFGWSL Conco1 EFSIDLLS--WKVDFKGLKFIPPG-VHLISTSLVTWVLEFDPETETDPFMGYYTKLSNYITPLVSKALLKLVEVDYKKDQHYDITKNMMDKSK-YLEYLILLGSYQLSFLTLYLGQKYTGLTYWKQVTELICQSPTYLEDFVVDYLETITQQFYEDFFASDLTNQLKNRFGFEA Conpu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Copci ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Croqu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ CryneH991 EFGIDGTF--HTVRFSGIKFLPPG-LHFIRQAFVRYAVHYNKDTENDKELAPYPSLTSHITTISQTVILMFVRFSLKRDGAVGVTVYSKDKSW-LLGNVILLGHLQLSFILFLQLSSYSSFLAYKRMLALLCQSSSFLISLYKELLKSLRVEIEDGVFDTLPEMDAWKKWMWDI Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Debha1 LMGIDTQF--FNINFRGIKLIPAG-IHLFRLGFWVLILRWDDALERYSYMVSYP-LNTSISEVIQEFLLRYTIIQFKENTESVVTENYLDKSW-YLSQL-MFGELQLSFINFVILGNFCSGLQWLNIIKLILMSKNFMKSVALDFLTIFQHHLDKEYLIDDLALNNKSKFNIDF Dekbr2 QVGIDTLF--YKTDFQGIKLIPPG-CHLIRVGRFVILISSEHSKDAKSIMDGFDNDTGNVTTTLE---MSVIDISDKVKAESKKMEDYLDRTW-IIEKEFYLAEFKFSFILAAILNNQGAYQQWKTLLDLFLRSGRLLKQESYEFLKNVNMQLKDDYQEDTFNIDLNSSFGMEI Dicdi TIGIDNKV--WTSGFKGVKMIPPG-VHMF-SSFIVFIKRWNKEEEDDKNLAPYPLLTSHITSLLDRILPYFSKIP-KIQNSTALSKWNIDKSE-CIEFIILLGEIEFCFVLFIFGMTWSGFQQWKELVTLFLSCDELVLKLFIEFFKILKNQLQNDMFESELSNRQQQN----- Dmel EFGIDLCA--YTIGFRGVKMIPPG-VHYVRVGFVIVVREWDHELEEERVLAPYDELTGSVTSCVDRCRPRFTTVPLRPQDALPVSRHALDCID-AVDKLLLIEELQLAYAFFLVGYSVESLAHWRKLLGLLAHSQTAVTKTYMKYSEVLAHQLPEELMVP-----LEKKLGWEF Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Falba TFGIDLAA--WSVKFRGVRMVPPG-VHVVRSAIFIRILHWADGDELSDVLAPFPGL-----SIFSQIRPAFPRLDILSASEQPRTLALQDRSP-QVEGHILLSQQALAFILLLVAPSSRALAHWRDAVGAWSACERLIASKYADFLYLLSGQLAADLFEDILNEAATERLGFEA Fomme1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Galma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Ganpr1 SLGIDFYH--WHTGFRGLKFIPPG-LHFVRTGFFVFVGRWDPAAEDAQNLGVYPSLTRHTDDTVRRILLAFLTFDLRPPDATGRTTYSLDKSW-LLRHVVLLGELELTFLLFHPANIFDGFEHYLNIVELVFAAEEAIRAFFHEFAEILTAQTSEEFVEESVSGNVRERFDWDI Gloin1 EFGIDNNC--WKIGFKGVKLIPPG-LHFVKTGFFIVIKYWDCTLEDDPFLGPYPHLTNFITRLISIILILFTKFDLKRPGATGVTKYSQDKSW-LLSDLFLLGELQLAFICFLIAENYAGFMQWKNIVLLICSCQEAIEKIFTDFLDVLKYQLERDFFHNIVTENLNQRFNWEI Hisca1 LIGIDLLS--FTSTFHGIKNLPPG-PHFLRNGEWIRLRQWDAGAEASGGLLAYDQLTDHITALLSRILLRFLPVDLKRAGAVGRTEAAQDRSW-ALGDLVILGELQFTFLMVLTLMNFSCQEQWKRLLGLVLTCRAAVLVFFVQVLRLLRLQLKDDVEGGLFDLDVKGRYGWEL Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lacbi2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Lenti61 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Malgl1 YVSIDQHA--YRTDFEGFKLVPPG-IHCLRSALFVLSRTYDPASDADKSLAPYPSMTRYLQATLARIFLAFTPFSLAPPDAHGRTRWSMDKSW-LLEDVMLLREFELSFLLFRCTNNAAALDHWAAIISLFCRAASYLGAAHLGWLEALVAQWQPHIW-TLASYESHARFAWSL Mellp23 QFSIDGHT--SITGFKGLKLLPPG-FHLIKHGLIIIIRRYDENEERDSNLAPYPSLTCFITELVEEVFTNWPKINLKPKDSIGLSKWSQDKSY-LFHQFIFLGHIQLSYLTFLLVHSFQSLETYQTLLNLLTKSS--------------------------------------- Mnele EFGVDYAS--WSTGFRGLKMIPPG-LHFIRTGFFIVVKRYDVQQETDKMLAPYPSLTTHITTTVTRLQMRFSKVD-KTVGYTALTEYYMDTTS-ALNSLILLGELQISFVVFLLGHVYSAFEQWKLLVDTICRAQQSLVQFYKAFIRTLHFHLKSDFFVDIVSRNLEKYYSWDF Monbr EFGIDYKS--WHTAFKGVKLVPAG-VHYVRIGYFVLIFKWDPTEEHDPYLAAYPSLTSKITATLARLQIPFVQVP-RPPGATPVTQHSLDRSY-TLQQVLLLAELQYAFVCFLVGQVYEAFETWKQLVALLCNSGQAIADLYIDFMGVLHYQLKSDFFFDIVASNAHQFKSWNF Morel2 EFGIDVNC--WNTGFKGIKIIPPG-AHFVRTGFWVVVMKWNAYNEEDPFLGSYPKLSNHIKPTISSVFISFTPINLRRKGAVGVTRYSLDKSW-LLNNLFFLGEYQAAFVTMLLSYHLGAFRQWKTMTILVCQSTEATSSLFSEFIQTLHHQLTSSFFMDLLFASVLESFEWKI Mucci2 EFGIDYNA--WTIGFKGVKLIPPG-LHFIRTGFFILVREWNPQIEDDRNMGPYPKLTNYITGLVRRVLMDFTAFDLRPTGASGVTRWSLDKSW-LAGQLLMLGELQLSFVCLLMAQNFSGFNQWKKLVHLLCSCHELMTELFIEFMDVLQFQLDEDFYRDILSEGIVNKFDWKV Mydma EVGIDYHS--WYTGFKGISNIPPG-FHMLRTSYFLLYRKYDKQLEDAKYLAPYPQHTNYINDLLQRVQIRFSKIP-DPLSTTPKTLHCIDSTY-FLKQFIILGELQFAFICFLLGQVYDAFDHWKALINLIASCQNYLSEFFCKFIDIVERQLEEDFFVDIVAQNIIERFHWDL Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Orpsp11 ----------------------------------------------EEALQTY---------------------------------------------------------------------------------------LFKDFLVILNDQLKHDFFYDILSGSLSKTFKWDL Pench1 LVGIDLIT--FTSTFHGIRDLSPG-WHFLRSGAWIYIWKWDANTESSGGLFKYRGLTDRISSLLSRVIFGFIPVDLKREGAVGRTEAAKDRSW-ALGDLILLGELQFTFLMVLTMMNYSCLQQWKRLLELILTSRSAILDFMSEVLRILSLQLQDDADGGLFEIDVKAEYDWEL Phybl2 EFGIDYHA--WTIGFKGVKMIPPG-LHFIRTGFFVAVREWNTHTEDDRNMGPYPTLTEHITGLVRRILMEFTPFDLRPKNATAITKWSIDKSW-LARDLLMLGEMQLSFVCLLMAQNFSGFHQWKQMVRLFCSCQEWMEEVFIDFIDTFEHQLEEDFFRDILSENLVSRFKWEL Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Plicr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Polpo SITLDNKQ--TVSGFKGYKMIPHG-VHLFQSRFFVGVEELDDDHDDDRNLAAYPSLTKHIAELLERLLPYYSVIP-SPKNSTPVSKWNMDKSD-SLQYVLIIGEIEFCYTLFIYGLAYSAFVQWKSLITLMLQCDRLVDELFGTLLEVLTLQMESDLFISDISSNVEQKFQWSL Pucgr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Punst1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhior3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Rhoto1 DFGIDGRL--WTVDFSGVKLLPPG-LHFFRHGILTVVEEWDNVQEEDKSLAAYPGLTSFVTETLARVVLEFVKFDVKPEGAVGLTRWSRDKSW-QLSHVVLLGELQLAFILFALLHNFSSLTAYKALFALICRSATLAQPLFASFLSLFLAQIQADFFATLPSLETMERFGWDL Rozal11 EFYAD-----------------------------------------DPFLGPYPKLTSHISKVVDKVLIIFTSIDLRPQNPSNLAKYGMDKSH-LLRSLILLGELQLAYLALLTAFNYDGFEQWKKIVALICYSEEAINQLFENFISILRVQLEDDFMVDLFSSELKTQFGWSF Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Salro ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schco3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Schpo1 YVGIDQSS--YEASLPGIRNVKGG-IHLFISGVFKYSIDFDSKSETDENF--YPLLTKFITQDLQRIFLNFAEFNLRSPSATGRSKQAIDKSF-LFQRLVALAELSISFLSYSILSHYGALEHWKNMLSLLLQSYELAETFYASFLELFKLQLSSDLETSAIFEKISELLNSHE Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Sphar EFGLDYKS--WTVGFKGVKFLPHG-IHMARTAFFVVVRKWDCDSEDDPFLGTYPNLTHFVTAVVQRHQFRFTEIP-RPSNATSVTQSYMDKTG-LLKHLLLLGELQFAFVSFLVGQCFDAFEHWKTMVHLLSWCDSAYVELFCDFVATLHWQLKEDFFIDIISKNVSDRFQWDF Spipu1 EFGVDCYS--WTTGFKGLKLIPPG-IHFVRTGFFVVVKRWNPSAEDDRFLGVYPRLTTHITQLIDRILLNFTPIDLKPSGASGVTKYSMDKSY-LLRQLLLLGELQLAFIIFLLGEVYDGYEQWKTFIHLLCQSDEAIDDLFYEFIGIFHAQLETDFFYDALSADVESRFKWDI Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Stehi1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Tapde11 QVGIDLLS--WTTGFRGIREIPRG-LHCLKFATWVLAYKWDRTTEAGHGI----RNSGHLSEVVQSIVFRFLPIDLKKPGSLGITRMSLDKSW-LLEDSIFLGQFEFCFLSVLLFTSITAFEQWNIMLRLVCSCRATIPKFYTAFLNLLQAQIEEELYADIFELTI-------- Thetr VVGVDGVG--WRVTFAGIKMLPLDMLHFVPTGFWVAVYRYEPKSEIDARLQPFPALSAPLTGLVAALMPRLAKFE-RLAQVTGRSAVGHDNSP-MLRAVAVVGEFAFAFLGVFLVSSGACFVGWRARFEAFAAARHIWADTFEVLLDLVVAQLDNELFADLLIEDARDRFGWEL Treme1 SVSLDGSS--NVISFSGYKFLPPG-LHLFRSAFIRIIISYSPKTETDPHLAGYDLLTSEIDRVLDDVIMNFPMFDLRKDGAVGVTRYSMDKSW-LLGNVILLAHFQLSFILFLHISSYSCLTVYRRLLSLFCRSSSFFMTFALTLLSTLSAQLKPDVFQTLPDMDCMRK-GWSL Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Umbra1 EFGIDYNA--WSTGFKGVKLIPPG-LHFVRTGFFVLVRKWSNETEDDNNLGPYPALTNYITSLLHRIFVEFTAFDPRPPGASGITKWSMDKTW-LTKELLLLGELQLAFVATLLGQNFTSFNQWKKIVQLLCSCQELVDELFSDFLDVLTKQMNQDFFYDILSENLQEKFHWEI Ustma22 QITVDAHSETYVINFSGIKSLPTG-WHCIRNVLLTAVRELDRLQQTEPRLLPYPQATRHLSQVVARVVLAFTRFELRPANSIGITRWSQDKSW-LLRDVALLCEFELAFVVFITANNAYAFEQWMDMVALFCRASSLIGAAHIAFLNTLHTHVFTDFWSSTTQQETSSRFGWSL Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ [Cluster3978.fasta_al_trimmed; alignment length = 243] Allma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 PAFSPLIALFEEHLASGE-ELGADICVNINGETVVELWGGYADNATKPWTRGTITPVWSVTKIVTALAALTLVDRLDPYAKVAQYWPEFAAHGKQDIEVRHVLSHTAGLPAW-DNTPLATQKLIQQQPWWTPGSASGYHLSTQGFLLGELVRRGKSLTQFIADEL-AAPLGA--DFQLGR-TADEQGASGGFGNARAINKIASMVTLGGFLSPQ-TGWGGSIADRKVTVTYTLNKMRAVYAAL Aurde31 ARFAEVEKIFQSLLDDGK-ELGASFFVNIDGKPVIDLWGGYADAATRPWERDTITTVWSTTKTITALAALILIDRLDPDEKVSKYWPEFAANGKENVLVKHFMSHTSGVAGW-DDLPSATAKLAAQAPWWEPGTASGYHSFCYGHLIGELVRRGKSLRQFVAEEI-AGPLGT-NDFQIGR-VAEDIGAGNGHGNARGVVRLLSVLALGGLLSPA-TGWGGSVGGRRITIGYVMNKMAAFYKAL Batde5 DGFDNVLDAFKANFEEGN-EVGASFAAYVGDTPVVELYGGYHNKRSKPYDKDSLQLVFSSSKFVEGIVITYLIDQLDFNERITTYWPEFGQGNKENVTVQCLLGHRAGVTYL--NLDQLAKLLAAQPHNFNGTLIQGYHAVTRGWYLNEIVRRKRTIGQIVRQEF-MPLLDA--EYYLAR-LSKEGPSYSGITNAKSLAKFAALMAQQGIISPE-TGVGGSMVDLHISFAYVMNSLAALVKAV Botbo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Botci1 PRLMELLEAFQGYLETGE-ELSASIVANIDEENVVDVWGGFHTHDTENWEHDTIVNVFSTTKTICALNSLILIDRLSINDTVHKFRAE-------------LESHA--------QIRL--------------------------------------------------------DFQAG--------------NCK----------------------------------------------- Caeel PGYEKVEKVFRRNFADGWEREGASITVYHKDRVIVDLQGGYADKAGRKWTPDTRTVVFSTTKAVGAVCVAMLVDRISYDDKMSKIWPEFAQNGKENITIDWLMSHRAGLAAL-DDFEKMSEVIASQKPNWEPGTKSGYHAITYGWIVDQIVRRGRSVGRFFKEEV-ADVHGI--DFHIGT-VSREQVAALGITKSRDLARLFSLVQQGKKFRAP-QGYGGSTVEDGITIAYVSNGLDSVFECL Canalb1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 PRFTKVKTIAQSYLNTGE-ELGFSLCVNVDGTDVVDLWGGYADAATKPWEKDTITCVWSSSKIVAALALLICIDRVDPSEKISTYWPEFAANGKEGVLVRHLLSHATGLSGW-HDLEKSTNLLAQQAPWWEPGTASGYHAYTMGHLITGLIQRHLPVDAFVKREI-TTPLDA--DFQFGR-VAEVLLASNGYSNARALVRIFSALSQSAFLSQK-TGWGGSQGERKITIGYVMNKMAAIYEAL Coere1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conco1 DKYVKVIDLFKSHFDNHI-DIGASVSVIHKDKVIFEVSGGYKDFEKDPYTKDTLQAIFSSSKVVTSIVVAWLVDQLDYDAPVSKYWPEFSQGGKDKVLLKDVMRHDAGLAWV-DDPEKLYNRLAQQAHVFDGEDKRSYHAFTQGFILNGIAQRKRTIGTILKEEI-TDKLGA--EFYYGD-VDPEIPAGNGHSTATSLAKIVSQAISENLFEEA-TGAGGSYVELEFVFAYVTNANKVFYEEF Conpu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Copci --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Croqu1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CryneH991 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Crypa2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fomme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Fusgr1 PQFQGVRDLLENYIKSNE-ELGASLTINVNDEVVVDIWGGHKDQEKEPWEENTIVNVFSSTKTVTSLAVLILVDRIDVNERVSKYWPEFGQNGKEDVLVRHLLSYASGVSGW-EDLDKSTPMLARQAPWWTPGTASGYHALTYGHLLGELIRRGKSLREFVATEI-AGPLDA--DFQIGR-VTPEIGAANGHANSRSLVRIMSAITLRGILKEE-TGWGGSFVDRRMTISYTMNKMKAIYDAV Galma1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ganpr1 EEFSDVRTAFFDNFRRGD-ELGAGFVVYYKNKMVVDLWGGYETPTSKLYTGTSLNVVHSSGKAIMSMVVCHFVSRFSWDTKVADIWPEFGEGGKENVTVKELLEHQGGVGFL-DNLDRLEQKIAGQPHNYSGKTTKSYHAVTRGWFLNALVRRKKTHGQLLRDWI-NPALGI--EVYCGR-VAPETPSGYTVTNARGLAKLAAVMVNGGLMDKK-TGMGGSCIEHHVAVGYVPNLMSAVVACV Gloin1 PEFSEIKNIFKKNIESGS-EIGASVTIYYNDKIIADLSGGIADWNGKLYDKDTLQLVFSSTKVLTSLVVAKFVEKLDYDEKISTYWPEFAQGNKENVTLSHLMTHSAGVGWF-DDLDSFSKILESQPHNFGGVPKRSYHACTRGYYLNEIIRRHRTIGQIVQEEI-MPTYDI--EFYYSR-VAQEGPSYSGITNSRSMAKLAAIMANNGLLNND-TGSGGSLFELKIGFAYCMNAFKETVNTV Hisca1 AAFAPVKDLLQKFIDAGE-ELGASITVNIDGRNVVDIWGGHRDTATSPWTRDTVTTVWSTTKAVTNLAALMLVDRLDLFEKVATYWPEFAANGKQDIEVRQLLAHTSGVSSW-EDLKISTERLAAQKPWWEPGTASGYHMQNQGHLVGELVRRGKSLKQFIAEEI-AGPLGA--DFQLGR-VAEAIGALNGHSNSRGVNGVLSAITLGGLLSQK-TGWGGSIAERRMTITYVMNKMKAIYAAV Klula1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lenti61 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Malgl1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mnele --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Monbr --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 EYYGQVLGYYTDLIAKSE-DLGGSLAVFVDGQPVIDVYTGFKDLATQAYDNTTLQQVYSSGKAVEGIIIARLVDQLDYEAKIVEYWPEFGQNGKEEVRLRDLMVHESGVPAL-DDEEKFSARLARQPHVFGGKPTRAYHAITRGWFLNEIVKRGRTIGQIAQQDLMTNYEDL--ELYYSR-LSPEGTSFSLKTNAHSLARLMSMMANKGLLSAK-TGAGGSMIELGIGFSYVTNAFRVVYARK Mucci2 DEYKEVYDLFVDSIKQGH-EVGASLAVYVDGKQVIGLQGGWQDVKKIEYTNNTLQMVFSSTKVLAAIVIAQLVDQLSYDERIATYWPEFAQNNKENVTLMDLMRHTAGVGAL-DDHAAFTKILAEQPHNFDGIPTHAYHAITQGWYQNEIVRRHRTIDDFAR-EF-KDKYGS--EWYLKR-IAPEGPSYSGHTNANSMAKLGAMMANRGLFAKDGTGAGGSLFKYNIAVAYAMNGYKAVFEKV Mydma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Neucr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pench1 PAFNRVRDLLQERLTSGE-EVGASLCVNINGKNVLDIWGGHANAATRSWEKDTLTVVFSSTKVVTALAALILVDRLNVEEKVSKYWPEFAANGKEDTEVWHILSHASGLPHW-DDTKASTDLLAAQAPWFKAGEASAYQLIDHGHLIGEIVRRGKPLKQFIADEI-AGPLGA--DFSLGR-TADEIGAINGFANARSLARIGSMVSLKGYLGLK-TGWGGSMLDRRMTIGYAMNKMNAIYEIM Phybl2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Picst3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Polpo --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Punst1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhior3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rhoto1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schco3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Schpo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar PGWEGVLDPIKKNFEEGY-EIGGHFTVYRKGEKVVDITFGYPDDSTTPYAKDTVQLVFSSTKFVCAMAMAMLVDRLAIDEPIATYWPAFAQNGKESVTVGDLMSHAGGVHGV-STLRSILEKTEMDPRTWRQMGNQGYHGISRGLYANEICKIHRSINTFLEEEV-LVPMGI-HDFRIGR-IGEHSPSTNGFTRAAVLARIANVFAHSGFMKPG-TGAGGSLITHEMAVAYTMNRYAEALEIS Spipu1 RGFEGVREAFERNFKEGE-EVGAGFYAWMDGKPVVELVGGFFDRDKKPYTEDSLNLVFSSSKAVTGIAIAHLISQLSYTDRIAKYWPEFAQGNKENVTVADLMGHRAGVSFL-DDLDALAEKIASQPHNFGGKPTVGYHATTRGWYINELVRRHRSLGTYIRQEL-ATPLNI--SYHLGL-VSPESGSFSGMTNAKGLSRFAAIMANGGVISSS-TGAGGSMIKEKLAIGYVMNSVKAFMDAV Sporo1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr AAAGAVAAAVRAAVAGNG-EAAARVAVYADGELVVDVSGGAAAATDAP--DDDLFVVFSCTKVLESLAVAILADRLDYDAPITDVWPGFAP-GNGSATLAHLMRHELGLPAL-DERTALAETLAVQMPMSAPGERTFYHAITRGLFVDEIVRRGRSLAHFVQEEI-AAPLGLVGELAIGR----GLTSAAGVTHARALAKIGSVLAGGGLLSPA-GGAGGAVFKINTAFAYTPSLLRAYLDAL Treme1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Trire2 PQFEALKALFQKNLDSKA-EIGASITVNLGGKNVVDLYGGFTDEATRPWEADTIVGVWSSTKGVTSLALLMLIDRVDPYEKVAKYWPEFAANGKEDIEIRHLLSHTSGLSAW-ENQDFAASKLAAQAPLWKPGSASAYHVFTFGVLITEVIRRGKSLKEFVAEEI-AGPLGA--DFQIGR-TSDDLGSLNGFTNARGMNRIFSVLALGGLLSQK-TGWGGSLFDRGLTFTYAMNQMRAVYESL Umbra1 PEYAHVKDLMLDNIIKGD-DVGAGVALYVDGQLKMDMYAGWMDRENLVYTNETLQMVFSCSKAMTGIVIARLVDKLSYDQTIATYWPEFAQGNKENVTLKDLMEHAGGVAWL-EDREKFSSRLAAQPHNWNGTKTRAYHALTRGWYLNEIVRRHRTIGQIAREEI-NHPYNV--EWHYNR-IATESPSFSGHTNARSIAKMAAMMANRGLLSAN-TGAGGSLFEFKIGFGYCMNSYEAIVTEL Ustma22 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster3981.fasta_al_trimmed; alignment length = 117] Allma1 --------------------------------------------------------------------------------------------------------------------- Ashgo11 --------------------------------------------------------------------------------------------------------------------- Aspfu1 KPPSPADFPPRATHPNILLLLHGDTAAA-FTSFARALN--LPETTIVTIQAVDEVIQGVLGYRPREILILGFGQGGMAALVAARLSGAISIGA--PTPVLLKQVFEFVEEMMPVMQF Aurde31 PPPTRKGLPSADGTDNLLILLHGDTEAP-FGKLGKSLN--LPQTATLALRGLSTALAHLTGWAPERVHLFGFAQGGSVAGEFAVLGSVVSVCGPLLTRVMLRRGFERVDEWTPIMAF Batde5 -MPTLKTISSNDKVNNILILLHGDTAAN-FVQFGVKMQ--LPQTAICAIAGTRSLICSFLGWPAERVFLLGFSQGGIMALDVALLGGVVSISGWI-TSVLVKSVLRRF--------- Botbo1 PVPQAPGIASDDGTDNLLILLHGDTHLH-FAKLGRQLR--LPQTATLALRALGKVLAYLISWSARQIHLFGFAQGGSVAAELGVLGSVVSVEGPLLTPVLVRKGYGAVEDWQEIMRF Botci1 RLPTVDDLPSRDGKNNILILLHGDTKNG-FTQLAKNLS--LPQTASLIPQATSMI--EMLNYPPRNIFMFGFGQGGMLALSTLALGGAISIGGRLPTPILIKSTFAEVEEVLPLMRF Caeel --------------------------------------------------------------------------------------------------------------------- Canalb1 --------------------------------------------------------------------------------------------------------------------- Cangl --------------------------------------------------------------------------------------------------------------------- Capow PHVQSSDISSRDGIDNLLILLHGDKCAP-FFKFAERMQ--LPQTAILALQALESLINDVLGWQRDRIFLLGFAQGGTVALDLALLAGVISISGTLTTPILLHNRFDRLEEMRAVMTF Catan2 --------------------------------------------------------------------------------------------------------------------- Cioin --------------------------------------------------------------------------------------------------------------------- CocheC53 RLPATTDFPPPSSQPNVLILLHGDTHEP-FTKLGQQLN--LPETACIAVQALDDVIRKGLGYKAREIMIFGFAQGGMVGLQVAALGGVISVGG--PTPVLVKDVFEYVEEMMPIMHF Coere1 --------------------------------------------------------------------------------------------------------------------- Conco1 --------------------------------------------------------------------------------------------------------------------- Conpu1 --------------------------------------------------------------------------------------------------------------------- Copci EQPRKNAIPSDDGTDNLLILLHG----------------------------MKKVIDHLVHWSLNQIHLFGFAQGGSVAAEYALFGSLVTVSGSLITPTLVKKGFQSVEEWEPIMKF Croqu1 AIPHFDDFPSADGVDNLLILFHGDTPKP-FTNLAKTLK--LPQTAFLILRALNHILNHLTGWHPSSIHLFGFAQGGSCAAEFVLLGSLVTISGPLLTPTLLSKGFAFVREWEPVMQF CryneH991 PIPSPSLLSSPDGKDNLLIMFHGDNKTS-FFNLAKQLN--LPSTAVLSLTALRKLLETLIGWRLEDIHLFGWGQGGTVALELGILGSIISICAPLLTPVLYKRGYREVEEWYGLMKF Crypa2 RIPKAEDFPSPPESTAILILFHGDADTS-FASFARSMN--LPGVLAITVRGVNRLIRETLGWELPDILLFGFGQGGSLAVGLASLKGVISIGGALPTPVLIRQEFVDVEEMLPVMQF Debha1 --------------------------------------------------------------------------------------------------------------------- Dekbr2 --------------------------------------------------------------------------------------------------------------------- Dicdi --------------------------------------------------------------------------------------------------------------------- Dmel --------------------------------------------------------------------------------------------------------------------- Enthi --------------------------------------------------------------------------------------------------------------------- Falba --------------------------------------------------------------------------------------------------------------------- Fomme1 PAPSKETIPSDDGTDNLLILLHGDTHQP-FGKLGRQLR--LPQTATLALRALSSVISHLTSWTPNQIHLFGFAQGGSVALETCLLGSVVSVGGPLLTPALIRKFFGGVEEWSPVMEF Fusgr1 RVPTEEDFPDPPESTTFLILFHGDHDVP-YAGFAKNLN--LPGVLGISVRGMEKLITEVLGWEMRDIMFFGFGQGGSLALGLAAFKGLISLGGPLPTSVLVKQEFDDVDEVLPLMQF Galma1 PSPKASRIASDDGTDNLLILLHGDTELP-FSKLGKSLK--LPQTAVLALRALSKVIDHLMAWTVSRIHLFGFAQGGSVAAEFGIFGSITTISGPLLTPVLVKKAYQSVQEWEPIMRF Ganpr1 KPPSRSNPPSPDGVDNLLVFFHGDSPRP-FMDLGRKMN--LPQTAIMSLKALARFFSDYVGWPAERVTLFGFSQGGSIAIDLALFSGVISIAGHLLTRILIKKAFDVTAEWAAIMQT Gloin1 --------------------------------------------------------------------------------------------------------------------- Hisca1 --------------------------------------------------------------------------------------------------------------------- Klula1 --------------------------------------------------------------------------------------------------------------------- Lacbi2 PLPKKSSIPSDDGVDNLLIFLHGDTHAP-FSKLGRQLK--LPQTAVLALCALSKVVDHLTQWPLNRIHFFGFAQGGSVAAEFGILGSIVTISGPLITPVLVSKAYQIIEEWEPIMQF Lenti61 TPPKSSAIPSDDGTDNLLILLHGDTQIP-FGKLGRQLH--LPQTATLALRAMDKVIAHLTAWPPHRIHFFGFAQGGTVAAEFALLGSIVSVSGPLLTPVLIKKGFAKVDEFEPIMRF Malgl1 PRPSSAGLPAPCGIDNLLLLLHGDTADP-FFSLGQRLQQTLPQTAVLSVQAITHLLTYLTGWAYEHMHALGFAQGGSVLLETLIFGSAVS-----------RRVFASSDHLRCRVRL Mellp23 PHPRLNQIPSPDDIDNLIVMFHGDTPKP-FSNLAKTLK--LPQTAFLIIRALNAVLDHLIGWHASTIHLFGFAQGGSCAAELLVLGSLVTVSGPLLTPTLLAKGFAFVQEWDPIMKY Mnele --------------------------------------------------------------------------------------------------------------------- Monbr DFPNAEWLPQRHRPDNLLILLHGDDEQK-FAALGRNMA--LPGMEVLSVRGLHGLLDELTGWHMRGVFLLGFGQGALTALDAGLLGGVMALSGGCFLPLHVKPWCKKLAQVRELFEY Morel2 PAPQKSSTPSIDNVDNLVIFFHGDKIEPNFTKLARSLQ--LPQTAAVCIQALIKFLKHCVGFNHRQIVLFGFSQGAEIALDLAALRAVISIAGYMMTKIMVRERIKPVPGWRPLMEF Mucci2 TPPNAKKTPSQDGIDNLLILLHGDSKAP-FAKLGQQLK--LPQTATLSVQAMDEMLQHLIGFNPSNIFFFGFSQGGTVALDAVCLGGVVSISGYLLGYILIEKRVRTI--------- Mydma --------------------------------------------------------------------------------------------------------------------- Neucr2 RIPQPEDFPSPPESTAILLLFHGDSDTP-FLSFARNLS--LPGVLAISVRGMGKLIGEVLGWELGDILLFGFGQGGGVALGLGSFKGIVSIGGALPTPVLVKREFENVEEVLPMMEF Orpsp11 ALKSSDFNDSKDKFNNILILFHGDNPTN-FINFGKKIS--LPQTAVVALRAVSRFVEVLVKYNYRQIFFFGFSQGGTAALDAAIIGGVISISGYLLVPIFIQDNAQFIVETRAIMEF Pench1 KTPTPSDFPSKSTSPNILLLLHGDTAAS-FTKFAEAIR--LPETTVVTVQGVSDVVRSTLGYALREIMVLGFGQGGMAALAIARLSGVISIGA--PTPVLLKQVFEFVEEMLPVMQF Phybl2 TPPQQSACPSSDGIDNLLILLHGDTKTP-FSALGPKLN--LAQTATIAVQAMAELLQHMVGFAPSNIFFFGFSQGGSVALDTVLLGGVVSISGYLLGYILVEKKFKAIGEWRVIHTF Picst3 --------------------------------------------------------------------------------------------------------------------- Plicr1 PAPNAARVPSDDGTDNLLILLHGDSHVP-FAKLGRALK--LPQTATLALRALDQLIT---AWPPHRIHLLGFAQGGSVAVEFAILGSVITVSGPLLTPTLVNKAFTHLEEWEPIMRF Polpo --------------------------------------------------------------------------------------------------------------------- Pucgr2 PAPSFPQLPSADGIDNLLIFFHGDTQIP-FSQLARKLK--LPQTACMSIRALIGMLDRLTGWTPEDIHLFGFAQGASCLSELALLASIVSVSGPLLTPVFLERGFQSVQEWKPILEF Punst1 PPPQPHSIPSDDGTDNLLVLLHGDSHEP-FASLGRQLR--LPQTAVLALRALTKVLRYLTHWRTDKIHLLGFAQGGSVAAEVALLGSVVTISGPLLTHVLLKKGFATLEEWEPIMRF Rhior3 IPPNSKKVSSQDGIDNLLILLHGDSKAP-FTRLGQQLK--LPQTATLSVQAMDELLDHLIGWNPPNIFLFGFSQGGTIALDTVLLGGVISISGYLLGYILIENKFKEIKEWRLIHTF Rhoto1 PKPQLAKVPSRDGVDNLLVLFHGDTAKP-FAHLGQSLN--LPQTAVLSLQALLALLDHLTGWHPSQIHFFGFAQGGSCAAELALLASLVAVSAPLLTKVCLKKGFEHVDEWREIMRF Rozal11 --------------------------------------------------------------------------------------------------------------------- Sacce1 --------------------------------------------------------------------------------------------------------------------- Salro PPPVPKCAPSTGGTRNVLILLHDGTEQE-MATLAARMQ--LSHFHCISVAALLRLVDSLVGYSPKGIFLLGIGQGGMAACQCALGGGDGSAVGPDPADVTL-------TAMRAIFGF Schco3 PKPSKSKVESDDGTDNLLIILHGDTHTP-FARMAKQLK--LPQTAVLALRALTRVVEYLTAWAPHQLHFFGFAQGGSVAAEFGLLGSIVTISGPLLTSVLVKKGFKEVEEWEPIMRF Schpo1 VLPSNACA---EGKDNVVILMHGDSHKS-FANMAKNVP--LPNTSYISLRGISNLIGNLLGILSSRIFFFGFGQGAMVALYSCYLGGIFSFGGTLPVPVYLRKTFKPFREWYTFVQS Sorma RIPQQEDFPSPPESTAILLLFHGDTNTP-FLSFASQLA--LPGVLAISIRGMDKLVGEVLGWETSDVLLFGFGQGGGVALGLGSFKGIVSIGGALPTPVLVEREFENVEEVLPMMEF Sphar --------------------------------------------------------------------------------------------------------------------- Spipu1 PPNPAHFPPSHDGVDNLLILFHGDTPEN-FINFGKKMR--LPQTSLLAIKGLVN----LLRWPAENIFLFGFSQGGVCAIDLALLGGAVSVSGWPSVKLLIKKRMTFLVEMRAIMAF Sporo1 --------------------------------------------------------------------------------------------------------------------- Stehi1 PVPKATCIPSDDGTDNLLILLHGDTHTP-FSSLGRSLK--LPQTATLALRALHDLVSHLTGWQLNQIHLFGFAQGGTVCAEFALLGSVVSISGPLLTPILVKKGFSSVEEWEGIMRF Tapde11 --------------------------------------------------------------------------------------------------------------------- Thetr --------------------------------------------------------------------------------------------------------------------- Treme1 PIPSPTLLSSPSGKDNLLIMFHGDTKQP-FFNLGKSLN--LPHTAILSLQALLELLSILTGWEMNKIHLFGWGQGGSMVLEIGYLGSITSICASLLTPICLRRAFKVVEEWMEIMRF Trire2 RIPSEADFPSPREATSILILLHGDNEAP-FAAFARNMS--LPGVLAISVRGMNKLVKEVLGWEMNDILLFGFGQGGSLALGLASFKGVVSIGGPLPTPVLVKREFADVEEMFPIMKF Umbra1 KSPDKKKTSSADNVNNILILLHGDTQEP-YKKLGINLK--LPQTATMAVQALSKLIQHLIHYQPSNIFFFGFSQGGTVALDQVLLGGVVSISGYLLGNILVEKKLEIILEWRAIHTF Ustma22 PLLASAALPSSSGVDNLLILLHGDNDSG-FFNLGQNLQKTLPQTAILTLQAVVALLDHLVGWSAGSIHIFGFGQGATLALEVLILGSIVSIHGSFITPVLHRKSTSALSEWDSVMSF Walse1 ELAQKRAIPSADGVDNLIIYLHGDNISQ-FINLSKKLH--LPQTASLVLEGLNDLIQTLTGWDHRNIHLFGFAQGGSVAVEYA-LGSVVNVLGPLLTPICINKAFIEVGEWSGILKF Zygro1 --------------------------------------------------------------------------------------------------------------------- [Cluster3997.fasta_al_trimmed; alignment length = 59] Allma1 ----------------------------------------------------------- Ashgo11 MENPHEKVQVGILARIVGNVERLNQSVATLNQELERILELMGQMCEHYGRATAFNLKTT Aspfu1 ----------------------------------------------------------- Aurde31 MENPHTERQAVLLERVLKNLENCHEAISELNRCIDDVISVAADLAQRYRKNVAYNLEAT Batde5 ----------------------------------------------------------- Botbo1 MESPHEEIQAVLLERIIKNADKLLEAIRELNHCVEEIVDIAAELFLNYRRNVQYNLGAR Botci1 ----------------------------------------------------------- Caeel ----------------------------------------------------------- Canalb1 MENPHEQTHNALLSRIINNMESLNESVVAVNKSLQQITEILSQMWENYIRNSEYNLEVT Cangl VENPYEEVQVNVLSRIIANVEKLNQSVRTLNQELENVLEVMGQICENYHRSVQFNLEAT Capow ----------------------------------------------------------- Catan2 ----------------------------------------------------------- Cioin ----------------------------------------------------------- CocheC53 MESPHEHQQSQLLSRIIVNVEKLNEAIMMLNKNLQEITELVAQMFKNYQSNVLFHLEAT Coere1 ----------------------------------------------------------- Conco1 ----------------------------------------------------------- Conpu1 MENPHAERQAVLLERIVKNASVCTEMMMEMNSCVEEIVKIAAELSTKYRKNVQYNLEAT Copci MENPHAERQAVLLERILKNTSKCTEMILELNHCLEEIVKIAADLSTKYRKNVQYNLEAT Croqu1 ----------------------------------------------------------- CryneH991 MENPHEAEQAVLLERIIKNVDKSNEAIIELNHCLKEYIHITSQLFSNYSRNVLYNLETV Crypa2 MESPHEHQQNLLLSRIITNVEKLNESIVVMNKTLQEIIELVAQMFKNYQSNVLFHLEAT Debha1 MENPHEQVQNALLSRIISNMENLNESIVTMNKSLQDITEMVAQMWENYSKNSEFNLEAT Dekbr2 ----------------------------------------------------------- Dicdi ----------------------------------------------------------- Dmel ----------------------------------------------------------- Enthi ----------------------------------------------------------- Falba ----------------------------------------------------------- Fomme1 MENPHAERQAVLLERIVKNSEKCIEVISELNHCLEEIVRTAASLVTKYRKNVQYNLDAT Fusgr1 MESPHEHQQNLLLSRIITNVEKLNEAVMVMNKSLQDIVELVAQMFKNYQSNVLFHLEAT Galma1 MENPHAERQAVLLERILKNTSKCTEMILELNHCLEEIVKIAADLATKYRKNVQYNMEAT Ganpr1 ----------------------------------------------------------- Gloin1 IGNPHEEQQRMLLGRIVNNVKKLNDALEDMNNRIQEIVVVLSKFWSNYNRNVTYNLENI Hisca1 ----------------------------------------------------------- Klula1 MENPYEKVQSNILARIIGNVERLNQSVVILNQELRRVLELMSQMCENYRESVDFQLQAT Lacbi2 MENPHAERQAVLLERIVKNTSKCTEMILELNHCLEEIVKTAADLATKYRKNVQYNLEAT Lenti61 MENPHAERQNVLLQRIMKNADKCTEAILELNRCLEEIVKTAADLVTKYRKNVQYNLEAT Malgl1 IENPYEERQTLLLERIIKNVDLLNEALMEMNRSFADIITIVAEMWNGYHRNVDFNMESN Mellp23 MQNPFEEQQTVLLSRMIGNIEKLSEAMEELTNALEECVFEFHQALEHYNLNVKYNLENQ Mnele ----------------------------------------------------------- Monbr ----------------------------------------------------------- Morel2 -MNPHQEQQAALLNRIALNVEKLNESLVQLNQKLEQVTMLIAQVWNSYSKSAHINLEGL Mucci2 MENPHEQQQIALLSRIIANVSKLNKSMEDMNTKLESIVVLISDMWNAYNGSVRIHIDDA Mydma ----------------------------------------------------------- Neucr2 MESPHEHQQNLLLSRIITNVEKLNEAVVVMNKALQEIIELVAQMFKNYQSNVLFHLEAT Orpsp11 ----------------------------------------------------------- Pench1 EESPHEHQQTVLLSRIITNVEKLNEAIMVMNKGLQEVVELVAQMFKNYQSNVLFHLEAT Phybl2 ----------------------------------------------------------- Picst3 MENPHEQAQNALLSRIINNMENLNESVVTINKCLQEVTEILSQMWESYLRNAEFNLEAT Plicr1 MENPHAERQAVLLERILKNTSKCTEMIVELNQCVEEIVKTAADLAQKYRKNVQYNLEAT Polpo ----------------------------------------------------------- Pucgr2 MQNPFEEQQTALLSRMLGNVEKLSEAMTELILTLESIASDLNQAVQNYALNVKYNLQNQ Punst1 MENPHNERQAVLLERIVKNSNKATELFMELNRALEEIIRTAADLVTKYRQNVKFNFEVQ Rhior3 ----------------------------------------------------------- Rhoto1 MNNPYEEEQQVVISRILGTVEKLNESMLELNRSIEQVTAEIVELWTSYMRNVQWNLQSQ Rozal11 ----------------------------------------------------------- Sacce1 MENPHEQVQANILSRIIGNVKRLNESVAILNQELVTILEIMGAICDNYHSSVQFNLEAT Salro ----------------------------------------------------------- Schco3 MENPHAERQAALLQRILKNVSKCNEAFHEVNTCMDEIVKTAAELAMKYKRNVLYNLEAG Schpo1 MNNPMEEQQSALLGRIISNVEKLNESITRLNHSLQLIVELASQMWANYARNVKFHLEET Sorma ----------------------------------------------------------- Sphar MDNPHSEQQHLLVDRIANNVEKLNDTVTSINTVMSDLIEKTAVVWSNYCRNM--NLKAG Spipu1 ----------------------------------------------------------- Sporo1 ----------------------------------------------------------- Stehi1 MENPHAERQAILLERIVKSADKCTELILEFNHCIQEIVNIAADLVTKYRKNVQYNLEAM Tapde11 MENPHQEQQNAIMSRIISNVEKLNEAVIELNRSLQVIVELVSQMWANYGRNAGFYLEGA Thetr ----------------------------------------------------------- Treme1 MENPHEAEQAVLLERIIKNVDKCNEAVLEMNHCIKEFTHVAAQLFANYSRNVNYNLEAL Trire2 QESPHEHQQSLLLSRIITNVEKLNEAIVVMNKSLQEIVELVAQMFKNYQSNVLFHLEAT Umbra1 MENPHEQQQNALLSRIVANVVKLNQVVTDLNERLEDIIALIAQMWSTYGSSVQIHLEST Ustma22 MENPHEERQSLLLERITKSVHRLNEALLELDRSVVEIITIVAELSEAYRRNAAFNMEAV Walse1 MSNPFEERQTVLLERIIKNVERCNEAFTELNKCVEDVTVITSKLFDNYNRNVNYNLKAI Zygro1 MENPHEQVQINILSRILSNVERLNQSVSTLNQELANILEIMGQICENYHNSIQFNLDTT [Cluster4000.fasta_al_trimmed; alignment length = 337] Allma1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Ashgo11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aspfu1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Aurde31 RIRARKKAQAKHEPAQFRDQVLKHLDDALFTRL-VSAGSSLEFLKYADELYEILIIGGLLQPGGCSFALVQAPNKKYVDVLNRLIR-RYKYLQKPLE-ESTLLQYVQK-WTPEQRDRLAYATGLMMAGLTGAGVLQSLTKEHLIKDDVSLNLLTRIIRAYLSEQNVDHLATTLRKGG--IKD-LTLFFPPN-KRTATHLQDHFMPQVAERQELISKLKEDALISSIWQAMMASVDWARPDQIEALALREVPVLEPFCT-TAKTQVALVNVVQLYCYE-DRRIMKAFQILKVLYNTDCISDQAIIYWYQKGAKPQGKQHFLAATEPLVKYLEA-QESD Batde5 KLKQRKEAVQKYEPEVFREQFLALIPDHYAEVI-EANDAKLDIKRYAEAFFELFLTGGLVAPGGNPFSIFAATTKARANILTKLAR-RLKYIPRKLE-ETHLLQYIHK-F-GDDADKLATSVGILTAGTLPLTVLGNTVKEHIVNDGKTLRFLTIALEAYIQEQSMDHLITAMRKSG--MDAKMPEFFPES-KRKDRDMAEHFLNKIADKEMTRQGLKDE-TMAIVWDGLMDSVDWSRGDQIETLAIKTVPLLVQFCT-SPKTEIALLTKIQVYFHN-ESRLMKHYAVVQNLYKHDVVSESGILYWFEKGVAPQGKTVFLKQMEPFVNWLKE-ADED Botbo1 RIKARKKAQAKHEPEIFQAQLYKHLEDNFAVKL-VSAGQTLEFLKYADALFEILLVGGLLQPGGSPFSIINAKEKKYVEVINKLIR-RYKYLQKTLD-QSNLLQYTSK-WGPALREKLAVAVSLFMSGLTSSAPLSTLTKDHLIKDEVSINFITVVFKTYLLDQSMEHLSATLKRGG--VKD-LLNFFPEN-KRDPKHLETHFLPQIAEKEAIVQKLKVD-LVGSIWQGLMGSVDWARPDQIEGLALREVSILEKFCN-GPKTEVALLNAVQVYCYE-DTRIMKAFQMLKVLYNKDVLSAQAIIYWHQKGAKPQGKQHFLKQTEALVKFLQE-QDSD Botci1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Caeel ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Canalb1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cangl ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Capow ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Catan2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Cioin ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- CocheC53 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Coere1 RIRTRKKAKAKYEPEVFRDSIFQLIESKISDAL-DAGGNTLDYHRYGDVFFDILVTGGLIAPGGVPFSLFVLGRRHWGDLIHKLTR-RYKYLESKFA-ESHVLRHIHR-YSEEENKILATGVAVLVSGFLTMEPLKALKEDHLTKDGLALRFLTEMLRVYLADNSINQLHKALVRAK--VGD-LIMFFPPN-KRDEDCFARHFMPELIERGELIDKVASQ-TIVLVWDGIMNAVNWFKAEHIEAQVLKQIEVLEVLTT-EPKSEIALLKHVQLYAHG-EPRLTKYFRIVLELYNTDVLSDSAIIFWFTKGAKPEGKSGFLKQTEALVRKLEA-LEAD Conco1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Conpu1 KIRARKKAHAKYEPSVFRDHLYKHLEDQITNKL-IQAGSTLDFSKYADALFEIILVGGLIQPGGSPFTIFNAKDRKYVDVLNKLIR-RYKYLQKPLE-TTGLLQYIHR-WEPSQKDKLSITIGLLMSGLASASCISGLAKDHLVKDDVAINVITIIFRSYLTDQSMEHLAGALKKGG--IKD-LLAFFPVS-RRGSKILEEHFLPQVADREGVISELQEE-LIQCIWVGLMQSVDWTRPDQIEGLALREVPVLEAFCS-GPKTEVALINTVQVFCYE-DTRIMKVFQMLKVLYNKDCVSDQAIIYWHQKGAKPQGKQHFLKATETLVKFLQD-QESD Copci RIKARKKAQAKHEPTVFRDQLYKYFEDAYTTKL-IQAGSSLEFLKYADVLFEIILVGGLLQPGGSPFTIFNASEKQYVEVLNKLIR-RYKYLQKPLE-ESGLLQYVNR-WTDAQKNKLCIAVGLLIAGLANASCLASLTKDHLVKNDVSISAITLIFRAYLSEQSMDHLSATLKRGG--IKD-LSAFFPPN-KRDNRVLEEHFLPQVAEKESIIRELAEE-VIGCIWQGLMSSVDWTRADQNEGLALREVPILEAFTS-GAKAQITLINIVQVHCYE-DTRIMKAFQILKVLYNKDVVSDQAIIYWHQKGSRPQGRQHFLKATEALVKFLQE-QEEE Croqu1 RNKQRKKAAAKFEPEEFRDQILKNLSESIASKL-DSLGNQLDYRKYEGPLFEILLVGGILAPGGSPFSIITSTKKKHVDVFNKLIR-RYKYLQKLFE-ENGLLQYINK-FEGPNMERLAYALALFISGLSSANVLLTLQKEHLVKDGISLKFVTKVFRAYLQVESADHLSGSLRRGG--VTD-IYGFFPPH-KRERIDLDSHFLDAIVTRDETLAHLKED-FIALVWAGLMHSLDMSRPDQIVDMVVKEVPVLAVFCS-NGRTQISLINTIQVWAYE-NTKVMAAFRILKELYAHDVVSDQAVLYWHSKGSKPQARQHFLKSSEPLVKFLQE-QDDD CryneH991 RIKQRKKATAKFEPEAFRDALLLHLADALVAKL-VQAGSTLEFLKYSEQLFELLFVGGLLQPGGSPVYILQPDDKGMIEVLKRVMQ-RYKYLQKPLE-ENGVLSYLPK-WDVKSREKLAEAIALLTILQISSRCLQSLAKEHVVKDNVALNFLTAFIKTYLSRQSIDQFGSTLRRSG--LKS-ILAVFPLQ-IRDRKHLEAHFLQVVNDKDETVQAVERD-ISEWIWLALMGTVDWARSDQIDTFVISHISILETFCQ-SAKAQVNLINAVQVYCYT-DTRIIKSFQILKVLYNADVVSDQAIIYWHQKGAKPNGKGHFLKVAEPLVKFLSE-QESD Crypa2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Debha1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dekbr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dicdi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Dmel RIKTRKDEREKYDPTGFRDAVIAGLEEQISKYL-DSAGNKLDYRRYGEVLFDILIAGGLLVPGGTSYCIFDAPERNHEQVFVKLIR-RYKYLEKMFE-EEKVLLFVKG-FTPSERIKLARMTALWLVGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQEKGIAYLIQALKKGG--LESKLMDFFPPN-KRTEEYFKQVFLNEIVKKRELQQALIDE-IIVIIWSTIMSLGEWKKEELVTDQAVRHLPLLQAFAS-TDRSELALILKVQEFCYE-NMNFMKAFKIILLFYKTEVLSEEIILRWYKEGHSNKGKMHFLEQMRKFVEWLQSAEEES Enthi ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Falba RDRRRKDIRARFDPEQFQELLLGVIKDALMRTF-NSNADRLQFEQSSSVFLEILFVGGILDAGGSPLSVIACADRHMVDIFLTIIA-RYRYMQDTLK-ETSLLIGLQANLTPEQISKLVTAFAMLCSMRVPVSALSALLKGYLVKDGIALKYLTAILKTMREASGIDALTLSLRRSD--LDTKLLEFFPEN-RRTYAELKSHFLSEITRREELQARLEAD-VTLVVWNAIMRSVTWSKSDLYEKQALRQVKLL-AFCTRSPTSELALMNAVQMFCHE-DQRFVRIFQLVAILYNEDAVSSEAIRYWYDKGAVNKGREGFRKQVDTLLKQIES-AEED Fomme1 KIKARKQASAKHEPAVFRDQLYKHLEDGYYNKL-VQAGSTLEFLKYADAFYEIFFTGGLLQPGGSPFSILKARDKKYIDVLNKLVR-RYKYLQRPLE-ETGLFQYCNR-WPAEQRDKFAIATGLIMAGLSTSAPLLSLAKDHLVKDFLALNVLTVIFRTYLVDQTMEHLNSTLRKGG--VKN-ILLFLPAN-KRDAKTLEDHFLPQVAERESVVKTLKED-FVGCIWQGLTGIIDWTRADQIEAVVLREVPVLEPFCE-SAKTQVALINAVQVYAYE-ETRVMKTFQILKILYNKDCISAQAIIYWHQKGAKPQGKQHFLKATEALVKFLEA-QEDE Fusgr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Galma1 RIKARKKAQAKHEPAVFRDQLYKHLEDAFATKL-VQAGSTLEFLKYADPLFEIILVGGLLQPGGSPFTIFNAKEKKYVEVINKLTR-RYKYLQKPLE-ESGLLQYIHR-WEPAQKDKLSIAIGLLISGLANASCLQSLVKDHLVKNDVAISVVTIVFRAYLVDQAMDHLSATLKRGG--VKD-LLAFFPPN-KRDGKHLEEHFLTQVAEKESVIKDLSEE-LIQCIWQGLLGSVDWARPDQIEGLALREVPILEPFCE-NGKTQIALINAVQVYCYE-DTRIIKAFQILKVLYNKDCLSDQAIIYWHQKGSKPQGRQHFLKSTEALVKFLQE-QESS Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 KIKTRKKAQAKYEPIVFRDSILKILSEEISQTL-DAAGNTVDFRKYGETLFEILLTGGVLAPGGSPFSIFSAQDKKHVEVFDKLIRQRYKYLQRSFE-DTNLLQYINK-WRSEENYKLATAIGLFASQMTNLNFLTVLFKEHLVKEGLSLQFVTAVFKAYLGEQSIEHLGGSLKKAG--IDNKLLEFFPPN-KRDEEYFARYFMKQLVEKEQTIDHVKED-FVQIVWDALMQAVDWTRPEMIENQASRQIEILAAFAS-NPKSEVALLQKIQIYCHE-DTRLMKHFLIVKILYEKDVVSENAIFYWYEKGAKPYGKGLFLKQMESFVNWLRTVETDS Hisca1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Klula1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Lacbi2 RIKARKKAQAKHEPSIFRDQLYKHLEDSFATKL-VQAGSTLEFLKYADALFEIILVGGLLQPGGSPFTIFNSEDKKYIEVLNKLIR-RYKYLQKPLE-ESGLLQYIHR-WSPAQKDKLSLAVGLLISGLANASCLQSLTKDHLVKNDVSVSVISLIFRAYLVDQSMDHLSATLKRGG--IKD-LLAFFPPN-KREGKYLEDHFLSQVAEKESIVKELSEE-LIQCIWQGLMTSVDWARPDQIEGLALREVPILEPFCT-GAKTQVSLINVVQVYCYE-DTRIIKAFQILKVLYNKDCISDQAIIYWHQKGSKPQGRQHFLKSTEPLVKFLQE-QEDS Lenti61 RIRARKKASAKHEPTVFRDQLLKHIEDAITNKL-VQAGSTLEFLKYADALFEILLVGGLLQPGGSPFSFLNAKAKQYVEVLNKLIR-RYKYLQRPLE-ETNLLQYLNR-WPEDQREKIAIAIGLLIAGLASASCLQSLTKDHLVKNDLSATTITLVFRAYLSMQSMEHLAGALKRGG--IKD-LTAFFPPN-KRDDKTVDDHFLPQIADKDGIIKALQEE-LMSCIWQGLISSVEWARQDQNEALALREIDILEPFCN-GPKTEVALINTVQVYCYE-DTRIIKAFQVLKVLYNKDCISDQAIIYWHQKGSKPQGRQHFLQAAQPLVKFLQE-QESE Malgl1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Mellp23 RNKQRKKAAAKFEPEEFRDQILKHLSEAVAAKL-DSLGNQLDYRKYEGPLFEILLVGGILAPGGSPFSIITSTKKKHVDVFNKLIR-RYKYLQKLFE-ENGLLQYINK-FEGPDMERLAYALALFMSGLASSNVLLTLQKEHLVKDGISLKFVTKVFRAYLQVETSDHLSGSLRRGG--VTD-IYGFFPPH-QRERSDLEAHFLDAIITRDETLAHLKEE-FIALVWAGLMHSLDMSRPDQIVDMVVKEVPVLACFCE-NGRTQISLINTIQVWAYE-NTKIMGAFRILKELYAHDVVSDQAVLYWHSKGSKPQARQHFLKSSEPLVKFLQE-QDDD Mnele RNKTRKDEKERYEPQVFRDAIIAGLEDQLLKYLCDTATGKLDVKRYGETLLDVLFVGGIISAGGTNICLISQEPKSFTNIFIQFIR-RYKWLQNRLG-EEKIIMVMRACLNDDERGLLGSATALLLIGIIPPTLLSGLTQDHLIKDDVSVTFATSLFRTWLQERDMASLTSTLKKAS--LDPSLQDIFPVGPKRSLDHIESYFLNEMVQRKLFVSRIKLY-AIQILFSAIANSGDWASSDIIQDDFYKELTLFKGIVK-THKLQIEFMNKIQEFCYD-NINFLKTFKVIFMLYHANVLEEDAIVEWYKSAHSNRGQTEFLSQMEKMVDWLENAEEED Monbr RIKSRKDEKVKFDPVAFSESLITRLNAE---YL-EEAGNSLDYRRYSDQFFDIFIAGGILAPGGSEFCVFRAGAKQYSTMLDKVLR-RFKYLQVLLE-EHKVLKFLKA-FTEEQRVALAKFMAQIMSGMCSAKPLNSLFQDQLVKDGFSEEFMFSLFRGWLAVSSINSLATSFRKGSIVIDKLL-LIYPLN-KRSEDHLIERILDDIVTKSELQATLTDD-VVTILWTALMDAVEWKKSDLIVEQALRQVRLLAHFTQNSEKAQLLLINKTQNYCYD-NQTIMKVFKIIMLLYHHGVIEEEAIRAWYDGRNSSKGRTVFLEQTAPLIEWLDTADVE- Morel2 KIRPRKKATAKFEPTVFRDAFISVLADEISVKL-DAAGNTLEYRRYAETLFEILIAGRLLAPGGSPFSIFQAQDRKHVDVFHKLMR-RYKYLQRGFE-DTNLLQYINK-FTPEDTNKLAMATGLFCSGLATLNVLSVLFKEHLVKEGLSLQFVTTVFKTYLIDQNVDQFGLNLYKAG--MSDRLLDFFPPN-KRDEDSFARHFMKQLVTKESVVENVKTE-FIPLVWTGMMASVDWTRSDQIDNQILKQVKLLAAFCT-SPKTEIALMQTIQVNFYE-DARFIKQFAVSQLLYKNDVLSESAILYWAEKGSKTQGRTVFMKQMEPFIHWLK--NASD Mucci2 RIKQRKKANAKHEPEIFRDQLLAQLKEAISSKL-DILGNTLEYRKYGDSLFEILITGGILEPGGSPFCLFAAEDKKYVEVFNKLIR-RYKYLQRIFG-ETNILQFINK-WQPEENSKLAKSTGFFICQLVPSSVLKVLLQDYLVKDGHALNFTTTVFRTVLDEQNIEQLGRILASEG--LNSRIIEFFPPN-KRDEDCLVRHFMKELVDKGSLLADLTED-VIPIIWQSMMNTVDLGRADQIEAQVLRAIKVLEFFCG-SPKTEIVLLQKVQSTCYD-DVRLAKYFRIIQTLYKNDVLSDNAILYWNDKAHLPQGKTIFLKQLEPFVVWLRD-N-ES Mydma RIKTRKDEKEKYDPTNFRDQIVAGLNEQASKFL-IQAGSKLDFRRYAEALFDILITGGILGPGGTSLCIFETEKRNMTSVFERMIR-QYKYLEKSLD-DEKVLMFMKG-FSDVQRERLAIAVYLLISGLSSPVCLSQIVNEHLTKDGIGLDFARTLFSVWLSEKDFPSLISMLKKSE--IDGKLLELFPLN-KRTIENFEAYFLNQIVEIQELKSRLKKE-VCILLWTSLMNAVEWKKEDLLAEQALRHLSVLQAFTP-ENEVELLLLQRIQEYCYD-NMNFMKLFKIIMLFYKTDVIGEDAIIRWYKDGHSAKGKSVFLSQMEKMVEWLQSAEEES Neucr2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Orpsp11 ------AKVVKHDPGSFQSSLLSPVIDKYLRII-EEQSNNLDFKRYSETLCELLIIGGQLVPGGNPMCLFQTDERKHVEVFEKLKR-RLKYLERAME-NSHILQHINN-WTELQNLKLETFIGIACAQLLPLSILSCLNKDYLVKEGASLRFITQVFKVYLQEQSIEHFTHNLKKSK--LDGNLLLFFPQN-KRSDEYLSRHFLQQIVDKKLTIKTLKTD-IVKCVWD----SIDFNKPDQMEANIKRQLPILEVFTT-SPKTEINLLCKVQKTCYE-DVKLMKYFHTIYCLYQGDVLSEAAILYWSDKAMLPSGKA-------------------- Pench1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Phybl2 RIKQRKKAQAKHEPEIFRDQVLKLLEEDISLKL-DAGGNTLEYRKYNDSLFEILITGGILEPGGCPFSIFGCADKNAVDVFNKLIR-RYKYLTRSFE-ETNILQYINR-WQPAENHKLAVATGYFVTQLGSLSVLKVLFKDYLVKDGLSLEFATTVFRTILSVQTIEQLGKSLINSG--LDSKLIELFPPN-KREDECLVRHFMKPLVEKDELAYKLKEE-IIQIIWVAILSTLDLARPDQVEAQTFRALKLMEAFAT-SPKTEIVLLQKAQLTCYE-DAKFTKFFQIVQLLYKNDVLSDNAILYWADKAHKPQGKTMFIKQMEPFVQWLKD-N-ED Picst3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Plicr1 RIKARKKAHAKHEPTVFRDQLYKHLEDSFATKL-VQAGGTLEFLKYADALFEIILVGGLIQPGGSPFTIFNSKEKKYIEVLNKLIR-RYKYLQKPLE-ESGLLQYIHR-WSSAQKDKLAIATGLLISGLANASCLSALTKDHLVKNDVSVSVITIIFRSYLVDQTMDHLSSTLKKGG--IKD-LLAFFPPG-KREGKSLEEHFLPQVADKEGIVRDLTEE-LVQCIWAGLMASVDWSRPDQIEALALREVPILEPFCN-GAKTEVALINVVQVYCYE-DTRIIKAFQILKVLYNKDCISDQAIIYWHQKGSKPQGRQHFLKATEPLVKFLQE-QEDS Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 RNKQRKKAAAKFEPEEFRDQILKHLSDAVAAKL-DTLGNQLDYRKYEGPLFEVLLVGGILAPGGSPFSILTSTQKKHVDVFNKLIR-RYKYLQKIFE-ENGLLQYINK-FEGPDLEKLAYSLALFISGLTSSNVLLTLQKEHLVKDGVSLNFITKVFTAYLQVESADHLSGALRRGG--VVD-MYGFFPPH-KREPSDLEAHFLDPIVARDETLVRLRED-FIALVWHGLMDRLDMSRPDQIVDMVVRAVPVLAAFCK-NARTQISMINTIQVWAYE-NTKVMGAFKIIKELYAHDALSEQAILYWHSKGSKAQARQHFLKSTEPLVKFLKE-QDED Punst1 RIKARKKASAKHEPTVFRDQLYKHLEDGFATKL-IQAGSTLEYIKYADVLFELLLVGGLLQPGGSPFSVFRAKEKNYVEVLNKLIR-RYKYLQKPLE-EQGLLQYIHR-WTPEQRDKLSIAIGLMLAGLASASCLQSLTKDHLVKNDVASNVLVTIFKAYLSEQSMDHLATALRKGG--VRD-LLAFFPPN-KREDKMLDEHFLPQVAERETIIAELKEE-LVACIWQGFVASIDWARPDQIEGLAMREVPVLEPFCN-GAKTEVALINVVQTYCYE-QTKIMKAFNILKVLYNKDCISDQAIIYWYQKGSKPQGRQHFLKATEPLVKFLQE-QEES Rhior3 RIKQRKKANAKHEPEIFRDNLLAQFKEAISSKL-DILGNTLDYRKYGDSLFEILITGGIIEPGGSPFCLFAAENKKYVEVFNRLIR-RYKYLQRILG-ETNILQYINK-YQPEETSRLAKSTGFFICQLISCSVLKVLLKDYLVKDGYALDFTTTVFRTILEEQSIEQLGRFLSSED--LNGRVIEFFPPN-KRDEDCLVRHFMKEFVDKGSLLNELSDE-VVPIIWQSVMSTVDVARPDQIESQVLRAIKTLEAFCT-SPKTEIVLLQKVQLTCYE-DVKLNKYFKMIQTLYKNDALSDNAILYWNDKAHLAQGKTLFLKQMEPFVTWLKE-NEES Rhoto1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Rozal11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sacce1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Salro -IRSRKDEKVKFDPNTFRDELVSGINEEVKNYL-VAQGDSMDYRRYAEQFFDIFIAGGILAPGGAEFCVFKTDGKEYFTALNEVLQ-RFKYLMVSLEKEEKVLRFIKA-FSPENMHKLATFVALLNSDLCSSKVLEALFIEALTKDDTAEKFIAAYFQAWLRNASLSSLASSFKKNK--LDKRLEELFPAN-KRSFEYMRERFLDDIISKKELQQQVVAD-MVPLVFSAVFSSVSWKKFDLMTEQALKQIKFLRAYTR-TQPAQVILLLRLQNYCVDSNQALMKIFVVLLLLF-----------------------KLLLFKLLLLLLLLLLLLLLL Schco3 RIKARKKAQAKHEPAVFRDQLYKHLEDAFTTKL-VQAGSTLEFLKYADALFEIILVGGLLQPGGSPFTIFNAPEKPYVDVLNKLIR-RYKYLQKPLE-ESTLLQYIHR-WTPAQKDKLALTTGLLIGGLASASCLQSLTKDHLLKNDVSIDVLTLVFRAFLTEQGMEHLASALKKGG--IKD-LLLFFPAN-KRDAKSLEEHFLPQVSDKDSLTADLRED-LVQCLWHGLMSSVDWARADQIESLALREVPILEPFCS-GPKSQVALINIVQVYCYE-DSRVMKAFQILKVLYNKDCISDQAIIYWFQKGSKPQGRQHFLKATEPLVKFLQE-QEEE Schpo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sorma ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Sphar RLRTRKDEKQKFDPGEFRDAVVTGLNDKSSRFL-DLAGNKLDFNRYGETLFDILFAGGILSAGGTTFCVFEMETLKMVETFDKLTR-RYKYLIRTMN-DNKNFKYLNI-FSEVHLERLAKFIGHVLSQMIEPTVLNGLLVEHLVKEEMSLNFITIVFKNWLSKASIESFAQVMKKAG--LDGRLIDFFPNG-KNNAAAIEEHFLPKVIEKYQFKQDIKQD-MIGLIFNSMMGTVDWKSTDLLEKDALNFIKILLAFCE-TPRAQLTLMLRIQGYCYD-NGPFMKIFKITMLLYNNDILEEPAIQKWYRDGHSIKGKSVFLKQMAPMIEWLNNAESES Spipu1 KLKQRKETVTKYEPEAFRDSLLKIIPEKYASIL-ELNESKVDYKRYGEPFFEFLIVGGLIAPGGNPFSIFAAEDRARVDIINKLTR-RYKYLQKRLE-ECHLLQYVNK-F-GENSHKLSRAVGRLISQLLPISVLTNLMKEHLVKDGASLQFVTGVFRSYLEDQPIDHLSTILKKAG--LDDKLLEFFPPG-KRQAEYVARHFLKPLVDKEQVKSKLNED-VVPIMWDALISSVEWGRPEQLESQIKTTLKVLAVFCT-SPKTEIGLMLKVQQMCYE-DGRFQKHYTIIRYLYDEDVVSESAIIYWFEKGAGASGKTLFVKQMEPFVNWLKS-QDDD Sporo1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Stehi1 RIKARKKAHAKHEPTIFRDQLYKHLEEVVTSKL-VQAGSTLEFLKYADALFDILIVGGLLQPGGSPFSVFQAKERKYVEVFNKLIR-RYKYLQKPLE-TSTLLQYVNK-WDQIQTTKFAMCTGLLIANLANASCLLSLTREHLVKNDHAIFVLAQIFRAYLAEASMEHLSTALKKAN--IKD-LSLFFPPN-KRDNKSLEEFFIPQVAEKEEITKIVHDE-VIACLWQGLMSAVDWARADQIEGLALREVPILEPFCN-GPKTEVSLINSVQVYCYE-DTRIMKAFQILKVLYNKDCISDQAIIYWHQKGSKPQGRQHFLKSTETLVKFLQE-QEEE Tapde11 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Thetr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Treme1 RIKQRKKAASKFEPESFRDALLLHLSDSLVAKL-VQAGATLEFLRYYEQLFEVLFLGGLLQPGGSPVYIVKEGE--IVETLKRVIQ-RYKYLQKPLE-ENSILGYIHR-WSPEARTKLAEALALIIVLQISPRCLSSLVKDHVVKDNIALDFLTSFFKTFLSKQNVDVLGSTLRKSG--LKD-IALVFPIQ-IRDKRHLAEHFLEKINEEKETVANVSRD-LVEWIWHGLMRALDLARADQSDSMVVHHIPVLEAFCN-GARAEVNLINAVQVYCYT-DTRVIKAFQILKVLYNADCISDQAILYWHSKGAKPQGKQHFIKVTEPLVKFLEA-QESE Trire2 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Umbra1 KIKQRKKAQAKHEPEIFRDSFLKPLNDDLSQKL-DVAGNTLDYRKYSDSLFEILIIGGILEPGGSPFSIFSATDRKHVEVFNKLIR-RYKYLQRSFE-ETNILQYINK-WTPEENNKLATAVGFFITQLASLSVLKTLLKDYLVKDGHSLQFVTATFKAILLDQSMEQLGRALISCG--LDSRLIDLFPPN-KRDEECLARHFMKPLVEKDEILDHMKED-AIQMTWTAIIDSVDLARPDQIEQTVMGYLSVLETFSN-SPKTEIILLQKVQLSCYE-NAKLTKFYQIVTLLYKEDVVSDTAIVYWSEKGIKPQGKNVFLKQMEPFIKWLRD-NAED Ustma22 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Walse1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Zygro1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- [Cluster899.fasta_al_trimmed; alignment length = 147] Allma1 LEKLVLNICVGESGDKLTRAAKVLEQLTGQTPVYSKARYTVRSFGIRRNEKIAVHVTVRGAKAEEILERGLKVKEYELNFSKMGHFGFGITEHIDLDIKYDPSIGIYGLDFYCVMGRAGFRVSRRKVGASHRITKDETIQWFKKKYD Ashgo11 IEKLVLNISVGESGDRLTRASKVLEQLSGQTPVHSKARYTVRTFGIRRNEKIAVHVTIRGPKSEEILERGLKVKEYQLNFSETGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMGRPGGRVSRRKVGNSHKTSKEDTIAWFKQRYD Aspfu1 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVAKRRIGSSHKITQAETIKWFKNRFD Aurde31 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFFVVMGRPGARVAKRKIGFSHRVKKEETQSWFKQRFD Batde5 LEKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRTFGIRRNEKISVHCTVRGPKAEEILERGLKVKEYELNFSQTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMGRPGLKIANKKVGAPHRVTKVETENWFKKRFD Botbo1 IDKLVINISVGESGDRLTRASKVLEQLTGQSPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPTIGIFGMDFYVVMGRPGARVARRKIGFSHRVKKEDTMSWFKQRFD Botci1 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPAIGIYGMDFYACMTRPGERVAKRRIGANHKIRRDETVKWFKNRFE Caeel ------------------------------------------------------------------------------------------------------------MDFYVVLNRNGVRVSKRRIGPSHRVDKEETIKWFQQKYD Canalb1 IEKLVLNICVGESGDRLTRAAKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLNFSATGNFGFGIDEHIDLGIKYDPSIGIYGMDFYVVMGRAGARVTRRKIGNSHKTNKEDTIQWFKTRYD Cangl IEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLNFSTTGNFGFGIQEHIDLGIKYDPSIGIFGMDFYIVMGRPGNRIARRKVGNSHKTSKEDTIAWFKQRYD Capow IEKLVVSICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTIRSFSIRRNEKIAVYATVRGPQALDILEKGLKVKEFELNFSDTGNFGFGIEEHIDLGLKYDPSIGIYGMDFYIVMGRPGQNINKKRVGVSHRISKAETMKWFQKKFD Catan2 LEKLVLNICVGESGDKLTRAAKVLEQLTGQTPVYSKAKYTVRSFGIRRNEKIAVHVTVRGAKAEEILERGLKVKEYELNFSQTGHFGFGITEHIDLDIKYDPTIGIYGMDFYCVMGRAGFRVSRRRVGAPHRITKDETIEWFKKKYD Cioin IQKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIACHCTVRGPKAEEILERGLKVREYELNFSKTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVMLARPGYNVRYRRVGFPHRLTKPDGMRWFQQKYD CocheC53 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSESGNFGFGISEHIDLGIKYDPSIGIYGMDFYVCMTRPGERVAKRRIGPSHRVNQAETIKWYKNRFE Coere1 IEKLVLNISVGESGDRLTRARKVLEELSGQSPIDSKARYTVRTFGIRRNEKIATHVTVRGPKAEEILERGLKVKEYELNFSATGNFGFGVDEHIDLGIKYDPSIGIFGLDFYLVMGRPGFRISRRKVGAPHRINKEETIEWYKKKFD Conco1 IEKLVLNICVGESGDRLTRAAKVLEALTGQTPVYSKARLTVRSFSIRRNEKIAVHVTVRGAKAEEILERGLKVKEYELNFSNNGNFGFGIQEHIDLGIKYDPSIGIYGLDFFVVLGRPGFRVGRRKVGVQHRLVKGDALNWFKTKYD Conpu1 IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFFVVMGRPGARVARRKVGCQHRVHKDDTMSWFKQRFD Copci IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPTIGIFGMDFYVVMGRPGGRVAKRKIGFQHRVKRDDTMAWFKQRFD Croqu1 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRSFGIRRNEKIACHVTIRGPKAEEILERALKVKEYELNFSETGNFGFGITEHIDLGIKYDPGIGIFGMDFFVVMGRPGFSVARRKVGSKHRVKKEDTMAWFRSRFD CryneH991 IEKLVINISVGESGDRLTRAAKVLEQLTGQTPVTSKARYTIRSFQIRRNEKIAAHVTIRGPKAEEVLERALKVKEYELNFSQTGNFGFGIEEHIDLGIKYDPGIGIFGMDFYVVMGRPGMRVATRKVGASHRVRPEQTVAWFKQRFD Crypa2 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVVRRRIGASHRITRDDTVRWFKQRFD Debha1 IEKLVLNICVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKISVHVTIRGPKAEEILERGLKVKEYQLNFSATGNFGFGVDEHIDLGIKYDPGIGIYGMDFYVVLGRAGARVTRRKIGNNHKTNKEDSIQWFKQRYD Dekbr2 IEKLVLNICVGESGDRLTRASKVLEQLSGQTPVQSKARYTIRSFGIRRNEKISVHVTVRGPKADEILERGSKVKEYQLNFSESGNFGFGIAEHIDLGIKYDPNIGIFGMNFYIVLGRPGFRVARRRIGRSHKVTKEDAINWFKAKYD Dicdi IEKLVLNICVGESGDRLVRAAKVLEQLTGQTPVYSKARYTVRSFNIRRNEQIAAHVTVRGEKAAEILEKGLKVREFELNFSTQGSFGFGIQEHIDLGIKYDPSIGIYGMDFFVVLSRPGFRVAHKKVGFQHKIGKEDAVNWFKTTYD Dmel IRKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILERGLKVREYELNFSSTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGYNVNHRKVGFQHRLTKEDAMKWFQQKYD Enthi IDKLVLNISVGESGDRLTRAAKVLETLTGQTPVLSEARYTVRAFSIRRNDQIACHVTVRGAKAAEILEKGLKVKEFELNFSATGNFGFGIEEHIDLGLKYDPQVGIYGMDFFVVLARPGFRVSRRKIGRDHLLTKEDAINWFKETYE Falba IAKLCLNICVGESGDRLTRAAKVLEQLTGQTPMFSRARYTVRQFNIRRNEKISCWVTVRGPKAAELLEKGLKVKEYELNFCDTGNFGFGIDEHIDLGIKYDPSTGIYGLDFYVVMNRPGFRVAQRRVGAPQRISKEETIQWFQKTFD Fomme1 ISKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSAMGNFGFGITEHIDLGARYDPNIGIFGMDFYVVMGRPGDRVSKRKIGFQHRVKREDTMAWFKTRYE Fusgr1 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPSIGIYGMDFYCCMTRPGERVTRRRIGASHRIKREETVKWFKSRFD Galma1 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGARVARRRIGFSHRIKKEDTMAWFKQRFD Ganpr1 LEKLCINICVGESGDRLTRAGKVLEQLTGQTPVQSKARYTVRTFGIRRNEKIAVHATVRGEKAMQILEQGLKVKEFELNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMGRPGFRVARRRVGAPHKVKKEETVEWFKKKFD Gloin1 IEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRSFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVLGRPGARVSRRRIGFNHRVTKDETIKWFKQRFD Hisca1 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMSRPGERVAKRRIGASHRINQAETIKWFKTPFQ Klula1 IEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLNFSATGNFGFGIQEHIDLGIKYDPGIGIYGMDFYIVMGRPGARVTRRKIGNSHKTSKEDTIAWFKQRYD Lacbi2 IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGARVARRRIGFQHRIKKDDTMAWFKQRFD Lenti61 IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRQFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPTIGIFGMDFYVVMGRPGARVARRKVGFQHRIKKEDTMGWFKQRFD Malgl1 VDKLVINISVGESGDRLTRATKVLEQLTGQTPVTTKARYTLRGFGIRRNEKIACHVTVRGAKAEEILERGLKVKEYELNFSDTGNFGFGITEHIDLGIKYDPGIGIFGMDFYVCMTRPGVRVSRRKVGAPHRVRKEETAAWFKQRFD Mellp23 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRSFGIRRNEKIACHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGITEHIDLGIKYDPGIGIFGMDFYVVMGRPGFRVARRKVGYKHKVKKEDTMTWFRSRFD Mnele ITKLCLNICVGESGDRLTRAAKVLEQLSGQEPCFSKARFTVRSFGIRRNEKISCWCTVRGAKAEEILERGLKVKEYELCFSEEGNFGFGIDEHIDLGIKYDPGIGIYGMDFYVVLGRPGYRVRYRRIGPKHKVTKEEAQKWFQTKFD Monbr LEKLCLNLCVGESGDKLTRAAKVLEQLTGQQPVFSKARYTVRTFGIRRNEKIAVSCTVRGQKALEILERGLKVKEYELNFSATGNFGFGIDEHIDLGIKYDPGIGIFGMDFYVVMGRKGFRVARRKVGAPHRIDKTDTMKWFQQQYD Morel2 LEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGIKYDPSIGIYGMDFFVCMNRPGNRITKRRVGANHRVNKEETMNWFKQRYD Mucci2 IEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRTFSIRRNEKISVHVTVRGPKAEEILERGLKVKEYELNFSQTGNFGFGIDEHIDLGIKYDPSIGIYGMDYYIVMGRPGNRVSRRKVGVNHQIKKEEAMEWFKQRFD Mydma IQKLCINICVGESGDRLVRAGKVLEALTGQTPVFSKARYTVRSFSIRRNEKIAVHCTVRGAKAEEILEKGLKVKEYELNFSATGNFGFGIAEHIDLGIKYDPSIGIYGMDFYVVLARPGYNIAYRKVGFPHRLTKADSMKWFQQKYD Neucr2 IQKLVLNICVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVSRRRVGATHRITRDDTVKWFKSRFD Orpsp11 LEKLCLNISVGESGDRLTRASKVLEQLTGQVPVMSKARYTVRTFGIRRNEKIAVHCTVRGPKAEEILDRGLKVKEYELNFSSTGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMGRPGFRVARRKVGFPHRNTKEETINWFKKRFD Pench1 LSKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTIRGAKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFFVCMDRPGARVAKRRIGVNHRITTAETMKWYKTKYD Phybl2 IEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGIDEHIDLGIKYDPSIGIYGMDYYIVMGRPGNRVARRKVGATHRIKKEESVEWFKTRFD Picst3 IEKLVLNICVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYQLNFSATGNFGFGIDEHIDLGIKYDPGIGIYGMDFYVVMNRAGARIARRKVGNSHRTNKEDTIQWFKQRYD Plicr1 IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGARIARRKIGFSHRVKKDDTMSWFKQRFD Polpo IEKLILNICVGESGDRLVRAAKVLEQLTGQTPVYSKARYTVRSFSIRRNEQIAVHVTVRGEKAAEILEKGLKVREFELNFSNNGSFGFGIQEHIDLGVKYDPSTGIYGMDFFVVLGRPGFRVCRRKVGFQHRITKEDTIQWYKSTYE Pucgr2 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRHFGIRRNEKIACHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGITEHIDLGIKYDPGIGIFGMDFFVVMGRPGYRVSRRKVGFNHRVKKEETMTWFRSRFD Punst1 LEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGMRVARRKIGFSHRVKKEDTMAWFKQRFD Rhior3 IEKLVLNISVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRSFSIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGIDEHIDLGIKYDPSIGIYGMDYYVVMGRPGYRVSRRKVGVTHRIKKEESIEWFKNRFD Rhoto1 IEKLVINISVGESGDRLTRAAKVLEQLTGQTPVTSKARYTVRHFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIAEHIDLGIKYDPGIGIFGMDFYVVMGRPGGRVARRKVGFSHRVKREETMAWFKQRFD Rozal11 IWKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKAAITIRQFGVRRNEKIAVHCTVRGPKAKEILERGLKVKEYELNFSNTGNFGFGIQEHIDLGIKYDPNIGIYGMDFYVVLSRPGFRVARRKVGRPHKLTKQDAIEWYKKTFD Sacce1 IEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLNFSATGNFGFGIDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKVGNSHKTTKEDTVSWFKQKYD Salro LEKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFRKARYTVRTFGIRRNEKIAVCCTVRGPKALEILERGLKVKEYELSFSTSGNFGFGINEHIDLGIKYDPSIGIYGLDFYVVMGRKGFRVARRKVGAPHRNSRDETMKWFQQKYD Schco3 IDKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTIRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGARVARRKIGFQHRVKKEDTMAWFKQRFD Schpo1 ISKLVLNISLGESGDRLTRAAKVLEQLSGQTPVFSKARYTIRRFGIRRNEKIACHVTVRGPKAEEILERGLKVKEYELNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMDRPGMRVARRKVGYTHKINAEDTINWFKQKYD Sorma IQKLVLNICVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPGIGIYGMDFYCCMTRPGERVSRRRVGATHRINRDDTVKWFKSRFD Sphar VRKLCVNICVGESGDRLTRAAKVLESLTGQEPVFSKARYTVRSFSIRRNEKIAVHATVRGPKAEEILEKGLKVLEYELNFSQTGNFGFGVQEHIDLGIKYDPSIGIYGMDFFIVMGRPGYCIAKRKVGYPHRCTKEETMKWFQQKFD Spipu1 LEKLCLNICVGESGDRLTRAAKVLEQLTGQQPVYSKARYTVRTFGIRRNEKIAVHCTVRGPKAEEILERGLKVLEYELNFSATGNFGFGIQEHIDLGIKYDPSIGIYGMDFYVVMGRPGHRIARKKVGAPHRVNKEETINWFKRRFD Sporo1 ------DISVGESGDRLTRAAKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSATGNFGFGINEHIDMGIKYDPGIGIFGMDFYTVMGRPGARVSRRKVGFSHRVKREETMAWFKTRFD Stehi1 IEKLVINISVGESGDRLTRASKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIAVHVTIRGPKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGARYDPGIGIFGMDFYVVMGRPGSRVAKRKIGPTHKVKKDDTMSWFKSRFD Tapde11 --------------------------------------------------------------------------------------------------------------------------------------------------- Thetr IAKLCVNICVGESGDRLMRAAKVLEQLTGQKPCMSKARYTVRSFSIRRGEKISVWCTVRGPKAYEILENALKVKEYELNFSDNGHFGFGIDEHIDLGLKYDPSVGIYGMDIFCVLGRRGERVGRKKVGTNHRITKEEGIKWFQQTFE Treme1 IEKLVVNISVGESGDRLTRASKVLEQLTGQSPVHSKARYTVRSFGIRRNEKIACHVTIRGPKAEEVLERALKVKEYELNFSETGNFGFGIEEHIDLGIKYDPGIGIFGMDFYVVMGRPGFRVGRRKVGYSHKVKPEQTIAWCKQRFD Trire2 IQKLVLNISVGESGDRLTRAAKVLEQLSGQTPVYSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGISEHIDLGIKYDPSIGIYGMDFYCCMTRPGERVTRRRIGASHRIKRDETVRWFKSRFD Umbra1 LEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRTFGIRRNEKISVHVTVRGAKAEEILERGLKVKEYELNFSETGNFGFGIQEHIDLGIKYDPSIGIYGMDFFCVMGRPGYRVARRRVGIQHKVKKDETIQWYKSRFD Ustma22 VDKLVVNISVGESGDRLTRATKVLEQLTGQTPVTSKARYTLRGFGIRRNEKIACHVTIRGPKAEEIIERGLKVKEYELNFSDTGNFGFGITEHIDLGIKYDPSIGIFGMDFFVCMTRAGARVARRKVGAPHRVKKEETAAWFKQRFD Walse1 VEKLVINISVGESGDRLTRAAKVLEQLTGQTPVTSKARYTVRTFGIRRNEKIACHVTVRGPKAEEILERGLKVKEYELNFSETGNFGFGVDEHIDLGIKYDPGIGIFGADFYVVMSRPGYRVAKRKIGFQHKVKKEEAQAWFRQRFD Zygro1 IEKLVLNISVGESGDRLTRGSKVLEQLSGQTPVHSKARYTVRTFGIRRNEKISVHVTVRGPKAEEILERGLKVKEYQLNFSETGNFGFGIQEHIDLGIKYDPSIGIFGMDFYVVVGRPGNRIARRKVGNSHKTSKEDTINWFKQKYD [Cluster989.fasta_al_trimmed; alignment length = 181] Allma1 MGAYKYLEELQKKKQSDLMRFLARVRVWERHLNAIHRASRPTRPDKARRLGYKAKQGFVVYRVRVRRGSRKRPVPK--GQTYGKPGVNQLKFQRSLQSVAEERVGRRCGNLRVLNSYWVNQDAVYKYFEVILVDPQHKAIRRDARINWITHKHRELRGLTSAGRKNRGWKRRNTLSLPRYR Ashgo11 MGAYKYLEELQRKKQSDVLRFLQRIRVWERQKTVIHRASRPSRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPK--GATYGKPGVNQLKYQRALRATAEERVGRRAANLRVLNSYWINQDSTYKYFEVILVDPSHKAIRRDARINWIVHKHREARGLTATGKKSRGWKRQNTLSLWRYR Aspfu1 MGALKYVEEIQKKKQSDVIRFLLRVRCWERQLNAIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPK--GATYGKPGVNQLKYQRALRATAEERVGRRCANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDPRINWIVHKHRESRGLTATGKKSRGWKIHNTQSYWRYR Aurde31 MGAYKYVSELYKKKQSDVLRFLMRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKHVPK--GATYGKPGVNHLKPQRGLRVLAEERVGRRCGNLRVLNSYWVNQDGVYKYYEVILVDPSHKAIKRDPRINWIVHKRREARGLTATGKKNRGWKRHNTLSLRRYR Batde5 MGAYKYLEELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKRQVAK--GATFGKPGVSQLKFQRSHKSVGEERVGRRCPNLRVLNSYWVNQDATYKFYEVILVDPQHKAIRRDPRINWIVHKHREARGLTAIGKKNRGWLRRNTLSLKRYR Botbo1 MGAYKYVSELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYLIYRIRVRRGNRKKPVPK--GATYGKPGVNHLKFQRSLQSTAEERVGRRCGNLRVLNSYWINQDGVYKYYEVILVDPHHKAITRDPKINWIVHKRREARGLTSTGKKNRGWKKHNTLSLRRYR Botci1 MGALKYLEEIQKKKQSDVLRFLLRVRCWERQLNVVHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPK--GATYGKPGVNQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYFEIILVDPQHKAIRRDPRINWIVHKHRESRGLTATGKKSRGWKKHNTLKLQRYR Caeel MGAYKYMQEIWRKKQSDALRYLLRIRTWHRQLSAVHRVPRPTRPEKARRLGYRAKQGFVVYRVRVRRGNRKRPVCK--GQTYGKPGVNELKNAKSKQAVAEGRAGRRLGSLRVLNSYWVAEDSTYKFYEVVLIDPFHKAIRRNPDTQWIVHKHREQRGLTSAGRKSRGWKRKNTKVFHRKR Canalb1 MGAYKYLEELQRKKQSDVMRFLYRVRCWERQKNVIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGGRKRPVPK--GATYGKPGVNQLKYQKSLRSTAEERVGRRASNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARYNWIVHKHREARGLTSAGKKSRGWKKHNTLSLWRYR Cangl MGAYKYLEELQRKKQSDVLRFLQRVRVWERQKNVIHRASRPSRPDKARRMGYKAKQGFVIYRVRVRRGNRKRPVPK--GATYGKPGVNELKYQRSLRATAEERVGRRASNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARYNWIVHKHREARGLTATGKKSRGWKRHNTLSLWRYR Capow MGAYKYLEELYKKKQSDVLRFLVRLRCWQRQLPAIHRASRPTRPDKARRLGYKAKQGYVIYRIRLRRGGRKRPVFK--GIIYGKPGVTQLKNQRSHRAIAEERIGRAIGGLRVLNSYWICQDSTFKYYEVIMVDTAHKAIRRDPRINWIVHKHRELRGLTAAGRKHRGWKRRNTLSLRRYR Catan2 MGAYKYIEELYKKKQSDVLRFLARVRVWERHLTS--------------------------------------------------------------------------------------------------------------------------------------------------- Cioin MGAYKYMSEVWRKKQSDVLRYLLRIRCWHRQLSSVHRASRPTRPDKARKLGYKAKQGFVIYRARVRRGGRKKPVPK--GATYGKPGVNQLKFARNLQSVAEERVGRHCGALRVLNSYWVAEDSTYKYFEVILADPMHKTIRRDPNIQWITMKHREMRGLTSAGKSSRGWKRRNTTQMRRKR CocheC53 MGALKYVEELQKKKQSDMMRFLMRVR---RQLKVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPAPKYTNKPTGKPGINQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYYEVICVDPQHKAIRRDPRINWIVHKHRESRGLTATGKKSRGWKRNNTLSLWRYR Coere1 MGAYKYLEEISKKKQSDVMRFLLRVRCWERQLHAIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKRPNPK--GQVYGKPGISELKLQKSKRAVAEQRVGKRCANLRVFNSYWVNQDSTFKFYEVILVDPSHKAIRRDPRINWIVHKRREARGLTSAGRKNRGWKRNNTLSLPRYR Conco1 MGAYKYVEELAKKKQSDIMRYLLRVRCWERQLNAIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGGRKRQQPK--GAVFGKPGINQLKSPRSHRATAEMRVGRRCGNLRVLNSYWVNQDGTFKYYEVILVDPSHKAIRRDARIQWIVHKHRESRGLTAAGRKNRGWKRRNTISLRRYR Conpu1 MGAYKYVTELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVPK--GATYGKPGVNHLKFQRGLRSVAEERVGRRCGNLRVLNSYWINQDGVYKYYEVILVDPSHKAIRRDPRINWIVHKRREARGLTSIGKQNRGWKKHNTLSLRRYR Copci MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGNRKKPVPK--GATYGKPGVNQLKPQRGLRSVAEERVGRRCGNLRVLNSYWVNEDSVYKYYEVILVDPNHKAIRRDPRINWIVHKRREARGLTSVGKQNRGWKRHNTLSLRRYR Croqu1 MGAYKYIEELQKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVKK--GATFGKPGVNHLKFQRSLRSTAEERVARRCGNLRVLNSYWINQDGVYKYYEVILVDPSHKAVRRDPRMNWIVHKRRESRGLTAAGKKNRGWRRNNTLSLRRYR CryneH991 MGAYKYLQELYTKKQSDVLQFVSRVRCWERQLAVIHRASRPSRPDKARRLGYKAKQGYLIYRVRVRRGNRKKQAPK--GATYGKPGVNHLKSPRGLKATAEERVARRCGNLRVLNSYWVNQDGVYKYYEVILVDPSHKAIRRDARINWIVHKHREMRGLTAEGKKNRGWKKHNTLSLRRYR Crypa2 MGALKYVEELQKKKQSDVLQFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPK--GATYGKPGVNQLKYQRSLAATAEERVGRRCANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRIDPRINWIVHKHREARGLTATGKKSRGWKKHNTLSLWRYR Debha1 MGAYKYLEELQRKKQSDVMRFLHRVRCWERQKTVIHRASRPSRPDKARRLGYKAKQGFVIYRVRVRRGGRKRPAPK--GATYGKPGVNQLKYQRALRATAEERVGRRASNLRVLNSYWVNEDSTYKYFEVILLDPSHKAIRRDARYNWIVHKHREARGLTSTGKKSRGWKRNNTLSLWRYR Dekbr2 MGAYKYVEELHRKKQSDVMRFLSRVRCWERQKNVIHRASRPTRPETARKLGYKAKQGFVVYRVRIRRGNRKRPVRK--GVNYGKPGINELKYQKPMRATAEERVGRRVSNLRVLNSYWVNQDSSYKYFEVICVDPFHKAIRRDPRYNWIVHKHREQRGLTSAGKKYRGWKVHNTLSLWRYR Dicdi MGAYKYLQELYKKKQSDAVRFLLRVRCWERNLPVCHRASHPTRVDKARRLGYKATQGFVVYRIRVRRGGRKRQVPG--GRTGGKPGVNELKPSRNLRSVAEERVGRRCPNLRVLNSYWVNQDSTYKYYEVILVDNSHNAIRNDPRYNWIVHKHRELRGLTSAGIKARGYKRRNTVVFHRYR Dmel MGAYRYMQELYRKKQSDVMRYLLRIRVWQRQLTKLHRSPRPTRPDKARRLGYRAKQGFVIYRIRVRRGGRKRPVPK--GCTYGKPGVNQLKPYRGLQSIAEERVGRRLGGLRVLNSYWIAQDASYKYFEVILIDTHHSAIRRDPKINWIVHKHRELRGLTSAGKSSRGWKRKNREHMHRKR Enthi MGAYKYINALNRKKQSDVLRFLRRIRCWERHLPRIHRVARPTNPERARRLGYKPKSGFVIYSVRIHRGNRKVSARK--GIVHRKPGIHKIKRVKSLQAIAEQRVGKHCGALRVLNSYFIGQDSTYRFFEVILVDPFNAAIRNDPKMNWIKQKRREARGLTSAAKKSRGLKRRNLLQLKRYR Falba MGAYKYLEELYKKKQSDVLRFILRVRCWERQLNTIHRASRPSRPEKARRLGYKAKQGYVIYRVRVRRGGRKRPVTK--GQTMGKPGVNQLKNSRNHRAIAEQRVGKVCGNLRVLNSYWINQDAMFKFFEVILVDPSHKAIKIDPRINWINHKHRECRGLTAAGRSSRGWKRRNAKVFHRYR Fomme1 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVPK--GATYGKPGVNHLKFQRGLRSIAEERVGRRCGNLRVLNSYWINQDGIYKYYEVILVDPNHKAIRRDARINWIVHKRREARGLTSIGKQNRGWKRHNTLSLRRYR Fusgr1 MGALKYVEELQKKKQSDVVAFLLRVRCWERQLNVIHRASRPSRLDKARRLGYKAKQGYVIYRVRVRRGGRKRPAPK--GATYGKPGINQLKYQRSLKATAEERVGRRCANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRIDPRINWIVHKHREARGLTATGKKSRGWKRHNTLSLWRYR Galma1 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVVHRASRPSRPDKARRLGYKAKQGYVVYRIRVRRGNRKKPVPK--GATFGKPGVNHLKFQRGLRSTAEERVGKRCGNLRVLNSYWVNQDGVYKYYEVILVDPNHKAIRRDARINWIVHKRREARGLTSIGKQNRGWKKHNTLSLRRYR Ganpr1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Gloin1 -----------------------------------------------------AKQGYVVYRIRVRRGGRKRPVPK--GATYGKPGVNQLKYQRSLKATAEERIGRRCSNLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDPRINWIKHKHREARGLTSIGKKNRGWLRRNTLSLRRYR Hisca1 MGALKYVEELQKKKQSDVIRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRQAPK--GATYGKPGVNQLKYQRSLRCTAEERVGRRCANLRVLNSYWINEDSTYKYFEVILVDPQHKAIRRDPRINWIVHKHRESRGLTAAGKKSRGWKRLNTQSYWRYR Klula1 MGAYKYLEELQRKKQSDVLRFLQRVRVWERQKNVIHRASRPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVSK--GATYGKPGVNQLKYQRSLRATAEERVGRRAANLRVLNSYWINQDSTYKYFEVILVDPSHKAIRRDAKYNWIVHKHREARGLTATGKKSRGWKRQNTLSLWRYR Lacbi2 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRVRVRRGNRKKHVPK--GATYGKPGVNHLKFQRGLRSTAEERVGKRCGNLRVLNSYWVNQDGVYKYYEVILVDPHHKAIRRDPRINWIVHTRREARGLTSIGKQNRGWKKHNTLSLRRYR Lenti61 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRVRVRRGNRKKHVPK--GATYGKPGVTQLKPQRGLRSVAEERVGRRCGNLRVLNSYWVNQDGVYKYYEVILVDPNHKAIRRDPRINWIVHKRREARGLTSVGKQNRGWKKHNTLSLRRYR Malgl1 MGAYKYLEELYKKKQSDVLRFLLRVRCWERQLNVVHRASRPSRPDKARRLGYKSKQGYVIYRVRVRRGNRKKHAPK--GATYGKPGVNKLKPQRSLRALAEERVGRKVSNLRVLNSYWVNQDGVYKYFEVICVDPHHKAIRRDARINWIVHKHRECRGLTGAGKKSRGYRKRQTLQLRRYR Mellp23 MGAYKYIEELQKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVKK--GATFGKPGVNHLKFQRSLRSTAEERVARRCGNLRVLNSYWINQDGVYKYFEVILVDPSHKVVRRDPRMNWIVHKRRESRGLTGAGKKNRGWRRNNTLSLRRYR Mnele MGAYKYMEELYKKKQSDLMRFLLRVRCWQRQLAAIHRASRPTRPDKARRLGYKNKQGVCIYRTRVKRGGRKKPVAK--GICYGKPGVNQLKFQRSIQSVAEERVGRACGGLRVLNSYWVGQDAVYKYYEVICVDPAHKAVRRDPRINWIVHKHRELRGLTSAGRKNRGWKRRNTLSLRRYR Monbr ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Morel2 MGAYKYLEELAKKKQSDVMRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKKPVAK--GATFGKPGVNQLKYQRSLQATAEERVGRKCGNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARINWIVHKRREARGLTSATKKNRGWKRRNTLSLRRYR Mucci2 MGAYKYLEELARKKQSDVSRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGGRKRPVPK--GATYGKPGVSQLKYQRSLRSTAEERIGRKCANLRVLNSYWVNQDATYKYFEVILVDPSHKAIRRDAHINWIVHKRREARGLTAIGKKSRGWKRRNTLSLRRYR Mydma MGAYKYLEELYKKKQSDLLRFLFRIRCWQRHLNAIHRASRPTRPDKARRLGYKAKQGFVIYRVRVRRGGRKRPVAK--GITYGKPGVNQLKFQRSIRSVAEERAGRYCGGLRVLNSYWIAQDSTYKYFEVIMVDPAHKAVRRDPRINWIVHKHRELRGLTAAGKKNRGWKKHNLVSLRRYR Neucr2 MGALKYLEELQKKKQSDVVRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRARVRRGGRKKPVPK--GATYGKPGVNQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYFEVILVDPQHKAIRRDPRINWIVHKHRESRGLTSTGKRSRGWKRHNTLSLWRYR Orpsp11 MGAYKYIEELYKRKQSDVLGFLGRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPNPK--GIVYGKPGIAELKYQRSTRATAEERVARKCGNLRVLNSYWVNEDATYKYYEVILVDPSHKAIRRDARINWIVHKHREAR------------------------ Pench1 MGALKYVEEIQKKKQSDVIRFLLRVRCWERQLNAIHRASRPSRPDKARRLGYKAKQGYVIYRARVRRGGRKRPAPK--GATYGKPGVNQLKYQRALKSTAEERVGRRAANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDARINWIVHKHRESRGLTATGKKSRGWKRQNTQSYWRYR Phybl2 MGAYKYIEELYKKKQSDVFRFLLRVRCWERQMNVIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGGRKRPVHK--GATFGKPGVNQLKYQRSLRSTAEERVGRKCANLRVLNSYWINQDATYKYFEVILVDPSHKAIRRDPRINWIVHKRREARGLTAIGKKSRGWKRRNTLSLTRYR Picst3 MGAYKYLEELQRKKQSDVMRFLHRVRCWERNKTVIHRASRPSRPDKARRLGYKAKQGFVIFRVRVRRGGRKRPVPK--GATYGKPGVNQLKYQRSLRSTAEERVGRRASNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARYNWIVHKRREARGLTSTGKKSRGWKRQNTLSLWRYR Plicr1 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRVRVRRGNRKKAVPK--GATFGKPGVNHLKFQRGLRSTAEERVGKRCGNLRVLNSYWVNQDGVYKYYEVILVDPNHKAIRRDARINWIVHKRREARGLTSIGKQNRGWKKHNTLSLRRYR Polpo ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Pucgr2 MGAYKYIEELQKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGNRKKPVKK--GATFGKPGVNHLKFQRSLRSTAEERVARRCGNLRVLNSYWVNQDGVYKYYEVILVDPSHKAIRRDPRMNWIVHKRRESRGLTGAGKKNRGWRRHNTLSLRRYR Punst1 MGAYKYVSELYKKKQSDVLRFLLRVRAWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKQAPK--GATYGKPGVNHIKPQRSLQSVAEERVGRRCGNLRVLNSYWVNQDGVYKYYEVILVDPSHKAVRRDPRINWIVHKHRELRGLTSTGKRNRGWKKHNTLSLRRYR Rhior3 MGAYKYLEELARKKQSDVSRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPK--GATYGKPGVSQLKYQRSLRSTAEERVGRKCRNLRVLNSYWINQDATYKYFEVILVDPSHKAIRNDARINWIVHKRREARGLTAVGKKSRGWKRRNTLSLRRYR Rhoto1 MGAYKYLTELQKRKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGFVVYRVRVRRGNRKRPVPK--GATYGKPGVNQLKFQRSLRSTAEERVARRCGNLRVLNSYWINQDGVYKYYEVILVDPSHKAIRRDARINWIVHKRRESRGLTSAGKQNRGWKRTNTLSLRRYR Rozal11 MGAYKYIEELYKKKQSDVLRFLMRIRCWERQLPAIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPNPK--GQVYGKPGINQLKAKRSHRALAEERVGRRCGNLRVLNSYWICQDATYKVYEVILVDPSHKAIRRDPRINWITHKHRECRGVTGAGKKSRGWKRRNTLSLRRYR Sacce1 MGAYKYLEELQRKKQSDVLRFLQRVRVWERQKNVIHRAARPTRPDKARRLGYKAKQGFVIYRVRVRRGNRKRPVPK--GATYGKPGVNELKYQRSLRATAEERVGRRAANLRVLNSYWVNQDSTYKYFEVILVDPQHKAIRRDARYNWIVHKHREARGLTATGKKSRGWKRQNTLSLWRYR Salro MGVYKYVEELYKRKQCDVLRFVLRIRAWKRQLTSVHRASQPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRKVSK--GAVCGKPGVNHLKFQRSKQSVAEERAGRRCGGLRVLNSYWVAQDATYKYYEVILVDPAHKAIRRDARINWIVHKHREMRALTSAGRKNRGWKRRNTLNWRRYR Schco3 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVPK--GATYGKPGVNHLKPQRGLRSVAEERVGRRCGNLRVLNSYWINQDGVYKYYEVILVDPNHKAIRRDPRINWIVHTRREARGLTSIGKQNRGWKRHNTLSLPRYR Schpo1 MGAYKYLEELAKKKQSDVNLFLSRVRAWERQMNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPK--GQTYGKPGVNHLKYQRSARCTAEERVGRYCSNLRVLNSYWVNQDATYKFFEVILVDPSHKAIRRDPRINWIVHKHRESRGLTSIGKKSRGWLRHNTLSLRRYR Sorma MGALKYLEELQKKKQSDVVRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKKPVPK--GATYGKPGVNQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYYEVILVDPQHKAIRRDPRINWIVHKHRESRGLTATGKRSRGWKRHNTLSLWRYR Sphar MGAYKYLEELYKRKQCDVLRFLLRMRAWQRQLTSIHRAPRPTRPDKARRLGYKAKQGVVIYRVRVRRGGRKRPVAK--GITYGKPGINELKWQKSHQALAEMRAGRACGNLRVLNSYWVTQDSTYKYYEVIMIDIHHKAIRKDPSMNWIVHKRREQRGLTSAGRKNRGWKKHNTLSLRRYR Spipu1 MGAYKYLEELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGNRKRLAPK--GQVYGKPGISELKYQRAARATAEERVGRKCPNLRVLNSYWVNQDATYKFFEVILVDPQHKAIRRDPRINWIVHKHRESRGLTAIGKKNRGWLRRNTLSLRRYR Sporo1 MGAYKYISELHKRKQSDVLRFLLRVRCWERQLNVCHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGNRKKPVSK--GATYGKPGVNHLKFQRSLRSTAEERVARRCGGLRVLNSYWINQDGVYKYYEVILVDPHHKAIRRDARINWIVHKRREARGLTSAGKQNRGWKKHNTLSLRRYR Stehi1 MGAYKYIGELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKHAPK--GATYGKPGVNHLKFQRGLRSVAEERVGRRCGNLRVLNSYWINQDGVYKYYEVILVDPNHKAIRRDPKINWIVHKRREARGLTSIGKQNRGWKKHNTLSLRRYR Tapde11 MGSYKYLQELYKKKQSDILRFLLRVRCWERQLAVVHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGGRKKPAPK--GATFGKPGINHLKYQRSLRTTAEERVSRRCSNLRVLNSYWINQDATYKFFEVIMVDPSHKAIRRDPRINWIVHKGRAQRGLTSIGKKSRGWKKHNTLSVRRYR Thetr MGAYKYLEELWKKKQSDALRFLQRVRCWERQLPSVHRLTRPTRPDKARRLGYRAKQGYVVYRVRVKRGDRKRRVRK--GAVTGKPGVRKIKQRRSKRSVAEERAGRRCGNLRVLNSYWVNEDAANRYFEVILVDPHHTVIRNDPRINWIVHKHRELRGLTAAGKKARGWKRHNTLSLRRYR Treme1 MGAYKYLTELYHRKQSDLLQFVSRVRCWERQLAIIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGNRKKPVPK--GATYGKPGVNHLKFQRGLKSIAEERVGRRCANLRVLNSYWINQDGVYKYYEVILIDPSHKAIRRDARVNWIVHKHRESRGLTSEGKKNRGWKKHNTLSLRRYR Trire2 MGALKYVEELQKKKQSDLVRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPAPK--GATYGKPGINQLKYQRSLKATAEERVGRRCANLRVLNSYWINQDSTYKYYEVILVDPSHKAIRIDPRINWIVHKHREARGLTATGKRSRGWKRHNTLSLWRYR Umbra1 MGAYKYLEELYKKKQSDVFRFLLRVRCWERQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRIRVRRGNRKRTAPK--GATFGKPGINHLKYQRSLQATAEERVGRKCANLRVLNSYWVNQDATYKYFEVILVDPQHKAIRRDARINWIVHKHREARGLTAIGKKNRGWKRRNTLSLRRYR Ustma22 MGAYKYVEELYKKKQSDVLRFLLRVRCWERQLNVIHRASRPSRLDKAHRLGYKAKQGYVVYRIRVRRGNRKKPVPK--GATYGKPGVNHLKYQRSLRATAEERVGRKCSNLRILNSYWINQDGVYKYFEVIAVDPQHKAIRRDARINWIVHKRRECRGLTATGKKSRGIRKRDTLQLRRYR Walse1 VGAYKYVQSINQHKQSDLVQFRLRVMAWYRQLTVISRAPGPSNVVRARQLGYKRKQGYVIYRVRVRRGNRKRQAPK--GATYGKPGVNHLKPSRGHRAIAEERVGRRCSNLRVLNSYWINQDGVYKFYEVILVDPSHKAIRRDARINWIVHKHRESRGLTAEGKKNRGWRKHNTLSLPRYR Zygro1 MGAYKYLEELQRKKQSDALRFLQRIRVWERQKNVVHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGNRKRPVPK--GATYGKPGVNELKYQRAMRATAEERVARRASNLRVLNSYWVNQDSTYKYFEVILVDPFHKAIRRDAHYNWIVHKHREARGLTATGKRSRGWKRHNTLSLWRYR END;