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{"sheet":"Table S3","index":0,"n_rows":62,"n_cols":28,"rows_kept":62,"cut":false,"hidden":false,"merged":[]}
[]
[null,"Table S3. Findings from trans-ethnic, fixed-effects inverse variance-weighted meta-analyses (P < 1 x 10-5, PCochran's Q > 0.10) with Illumina 450K Infinium Methylation BeadChip annotation"]
[null,"Chr","Position (B37)","CpG","Pollutant","Duration","Beta","SE","P value","FDR","nobs","Direction","PCochran's Q","Infinium Design Type","Strand","Probe SNPs","Probe SNPs within 10 bases","UCSC RefGene Name","UCSC RefGene Accession","UCSC RefGene Group","UCSC CpG Islands Name","Relation to UCSC CpG Island","Phantom","Enhancer","HMM Island","Regulatory Feature Name","Regulatory Feature Group","DHS"]
[null,20,43926884,"cg19004594","PM10","28 days",3.1577789534449402E-4,5.7176334845443198E-5,3.3349218902709501E-8,7.7535766726137901E-3,8622,"+-++++-+++++",0.62844651970899201,"I","R",null,null,"MATN4;MATN4;MATN4","NM_030592;NM_030590;NM_003833","Body;Body;Body","chr20:43926594-43927171","Island",null,null,"20:43360020-43360585"]
[null,3,35785890,"cg24102420","PM10","1 month",-4.9565304029880399E-4,9.1385201005717598E-5,5.8352355819041098E-8,2.7133436989363401E-2,8575,"------------",0.418855716369395,"II","F",null,null,"MIR128-2;ARPP-21","NR_029824;NM_016300","TSS200;Body"]
[null,7,117299297,"cg12124767","PM2.5-10","1 month",-5.3975855586929297E-4,1.01315091422291E-4,9.9560763448299296E-8,4.6295058078115001E-2,8577,"---------+--",0.83822560523936795,"II","R",null,null,"CFTR","NM_000492","Body",null,null,null,true]
[null,19,55013954,"cg19547155","PM10","1 month",-1.20526346789452E-3,2.3139163701434799E-4,1.9010697766269599E-7,4.4199206932154997E-2,7476,"-?----------",0.99666659859838103,"II","R",null,null,"LAIR2;LAIR2","NM_002288;NM_021270","TSS200;TSS200"]
[null,7,73183394,"cg12169661","PM10","7 days",7.1537409366712404E-4,1.3981722446224201E-4,3.1126595973318199E-7,0.14473649241421099,8619,"+-+++--+--++",0.11138904496018601,"II","R",null,null,"CLDN3;CLDN3","NM_001306;NM_001306","3'UTR;1stExon","chr7:73183379-73185115","Island",null,true,"7:72820924-72823026"]
[null,9,132383003,"cg09731694","PM2.5","1 month",-5.2291120377991095E-4,1.02282697018753E-4,3.1807255138143702E-7,4.93005032948362E-2,8580,"-+++-+------",0.196124439907741,"II","F",null,null,"C9orf50;C9orf50","NM_199350;NM_199350","1stExon;5'UTR","chr9:132382432-132383004","Island",null,true,"9:131421972-131422825","9:132381722-132383326","Unclassified"]
[null,11,114493710,"cg20057398","PM10","28 days",2.6635095058846899E-4,5.2941367056149303E-5,4.8778716065756599E-7,5.6704403798910903E-2,8617,"++++++++++++",0.51081222546932203,"II","F",{"$nulls":9},"11:113998908-113999055"]
[null,7,107385716,"cg14590325","PM2.5-10","1 month",-8.25784051901066E-4,1.6454022221076999E-4,5.2012379368520203E-7,0.120926961598532,8574,"--+---------",0.74728307400592198,"II","F",null,null,"CBLL1;CBLL1","NM_024814;NR_024199","Body;Body","chr7:107383657-107385021","S_Shore"]
[null,2,64682236,"cg01948201","PM2.5","12 months",-6.4060701435041697E-4,1.29042508565164E-4,6.8945747629360495E-7,0.24490439571394301,8575,"+-----+-+---",0.266904787297641,"II","F",null,null,"HSPC159","NM_014181","Body","chr2:64681011-64682237","Island",null,null,"2:64534584-64535741"]
[null,6,159466542,"cg16180082","PM10","365 days",-9.8523069617453504E-4,2.0058225854585599E-4,9.0219390072927199E-7,0.209756924240903,8617,"---+-+----+-",0.12439179154468499,"II","F",null,null,"TAGAP;TAGAP;TAGAP","NM_152133;NM_138810;NM_054114","TSS1500;TSS1500;TSS1500",{"$nulls":5},"6:159465693-159466558","Promoter_Associated"]
[null,5,88307760,"cg02412399","PM2.5-10","1 month",-4.6875913355168698E-4,9.56730348601903E-5,9.6034354587285795E-7,0.14885100880868599,8575,"-++---------",0.21163083210140701,"II","F",{"$nulls":8},true]
[null,22,30639730,"cg07316313","PM2.5","12 months",-6.7318802563670198E-4,1.3838353029095601E-4,1.14657072828134E-6,0.24490439571394301,8568,"------+-----",0.73097244603480205,"II","R",null,null,"LIF","NM_002309","Body","chr22:30639729-30639994","Island",null,true]
[null,10,102473022,"cg13583895","PM10","1 month",-4.0959880037236702E-4,8.4997008174650396E-5,1.4429471436036601E-6,0.22365344038189899,8582,"------+--+--",0.94406803012930796,"II","F",{"$nulls":5},"chr10:102473206-102474026","N_Shore"]
[null,7,27225396,"cg24988255","PM2.5","12 months",-7.7435712499980005E-4,1.6129633355735801E-4,1.5800521451760099E-6,0.24490439571394301,8581,"+-----------",0.45474513997117,"II","F",null,"rs61741589","HOXA11AS;HOXA11","NR_002795;NM_005523","Body;TSS1500","chr7:27225050-27225629","Island",null,null,"7:27190555-27192145"]
[null,19,18549689,"cg01065977","PM2.5-10","1 month",1.02946952866023E-3,2.15709404137909E-4,1.81968202207577E-6,0.16922788049821499,8578,"+++-++-+++++",0.55582804501146699,"I","F",null,null,"ISYNA1;ISYNA1;ISYNA1","NM_016368;NM_001170938;NM_001170939","TSS1500;TSS1500;TSS1500","chr19:18543828-18549161","S_Shore",null,true]
[null,10,135342413,"cg25330361","PM10","365 days",9.9125521617054492E-4,2.0800462790070899E-4,1.88344744892612E-6,0.23338615462708301,8617,"-+++++++++++",0.69379765076255095,"I","R",null,null,"CYP2E1","NM_000773","Body","chr10:135341255-135342561","Island",null,null,"10:135192257-135192927","10:135342406-135343123","Unclassified_Cell_type_specific",true]
[null,7,15726411,"cg18580296","PM2.5","1 month",-2.9628991784940302E-4,6.2294192883019801E-5,1.9717263559112699E-6,0.22920973835356301,8578,"-----+------",0.40047427621548098,"II","R","rs917442",null,"MEOX2","NM_005924","TSS200",{"$nulls":4},"7:15692873-15693735"]
[null,8,144790656,"cg09754549","PM10","365 days",1.73767969093267E-3,3.6562313709555402E-4,2.0076530582359999E-6,0.23338615462708301,8618,"+--++-++++++",0.403461562805003,"II","F",null,null,"LOC100130274","NM_001162914","TSS1500","chr8:144788491-144791059","Island",null,null,"8:144860480-144863032"]
[null,4,8230847,"cg01945624","PM10","2 days",-2.2815181003117601E-4,4.8114740852585802E-5,2.1179874154606801E-6,0.98484932227730804,8619,"-----++-+---",0.51220969793802196,"II","R",null,null,"SH3TC1","NM_018986","Body",null,null,null,true,null,"4:8229970-8231542","Unclassified",true]
[null,18,11855,"cg25023094","PM2.5-10","12 months",1.0273457910027399E-3,2.17402445683205E-4,2.2949510249857001E-6,0.36400091619059999,8578,"+++-++++-+++",0.58759368866916795,"I","F","rs6505962",{"$nulls":4},"chr18:11708-12372","Island",null,null,"18:1668-2363","18:11623-11949","Unclassified_Cell_type_specific",true]
[null,5,35617730,"cg11438448","PM10","28 days",-3.8815992506740398E-4,8.22738459725147E-5,2.3828947067930801E-6,0.22160587167916701,8625,"------------",0.96996524663058503,"II","F",null,null,"SPEF2;SPEF2","NM_024867;NM_144722","TSS1500;TSS1500","chr5:35617855-35618339","N_Shore",null,null,null,"5:35617465-35618744","Promoter_Associated"]
[null,6,30421218,"cg26690915","PM10","7 days",-3.3678207078513799E-4,7.1659170734528199E-5,2.6044665351259399E-6,0.60552935378390704,8621,"-----++-----",0.36918462285544501,"II","R",{"$nulls":5},"chr6:30418844-30419630","S_Shore",null,null,"6:30528709-30529646","6:30420915-30421864","Unclassified"]
[null,7,48963408,"cg05563813","PM2.5-10","12 months",-5.3727165415037403E-4,1.14497725372732E-4,2.6998938570502899E-6,0.36400091619059999,8554,"------------",0.49558329051762601,"II","R",null,null,"CDC14C","NR_003595","TSS1500","chr7:48963967-48964348","N_Shore"]
[null,1,104068488,"cg07878955","PM2.5-10","1 month",-3.0901654816738601E-4,6.59690392948637E-5,2.8096451720887802E-6,0.217744222917513,8581,"+-----+-----",0.57648534244330696,"II","R",null,null,"RNPC3","NM_017619","TSS200","chr1:104068487-104068913","Island","high-CpG:103840904-103841449",null,"1:103840702-103841560","1:104067619-104069204","Promoter_Associated_Cell_type_specific"]
[null,10,131592483,"cg02656060","PM2.5-10","12 months",3.4373274630381499E-4,7.3730462985149798E-5,3.1312378138217101E-6,0.36400091619059999,8575,"+-++++++++++",0.72157688232089801,"II","F",{"$nulls":5},"chr10:131592393-131592616","Island",null,null,"10:131482384-131482606"]
[null,7,2968595,"cg22989995","PM10","28 days",2.1306310543519E-4,4.57511645923315E-5,3.2085276283399602E-6,0.248657147914114,8620,"++++++-+++++",0.67214613177091098,"II","F",null,null,"CARD11","NM_032415","Body","chr7:2968234-2968596","Island"]
[null,1,71512973,"cg15201877","PM2.5","12 months",-6.5444492800376098E-4,1.4080089064414701E-4,3.3514136048647902E-6,0.25037804679363102,8577,"-+-+----+---",0.58357642767487605,"II","F",null,null,"PTGER3;PTGER3;PTGER3;PTGER3;PTGER3;PTGER3;PTGER3;PTGER3;PTGER3;PTGER3","NM_198718;NR_028294;NM_198714;NR_028293;NM_198716;NM_198717;NR_028292;NM_001126044;NM_198719;NM_198715","1stExon;Body;1stExon;Body;1stExon;1stExon;Body;1stExon;1stExon;1stExon","chr1:71512224-71513804","Island",null,true,"1:71284815-71286418","1:71512684-71513685","Unclassified_Cell_type_specific",true]
[null,19,40736427,"cg15153957","PM2.5-10","1 month",-6.5731283044044597E-4,1.4158273320215699E-4,3.4404222321035501E-6,0.22785288223907699,8576,"------------",0.31280479209765,"II","F","rs79228552",null,"AKT2","NM_001626","3'UTR","chr19:40732075-40732665","S_Shelf"]
[null,17,57233042,"cg02573089","PM2.5","12 months",1.21955148245566E-4,2.63759813300953E-5,3.76918862768992E-6,0.25037804679363102,8578,"++-+++++++-+",0.53059505781716099,"I","F","rs80342392",null,"PRR11;SKA2;SKA2","NM_018304;NM_001100595;NM_182620","TSS200;TSS1500;TSS1500","chr17:57231855-57232655","S_Shore",null,null,"17:54586469-54588061","17:57232097-57233543","Promoter_Associated",true]
[null,12,131865279,"cg00014484","PM10","28 days",3.4080783818458E-4,7.3738006762591102E-5,3.80287439303894E-6,0.25261571037747999,8601,"+++++-++++++",0.560238422033564,"I","F",{"$nulls":8},true,"12:130431230-130431297"]
[null,6,49755105,"cg21080533","PM2.5-10","1 month",-5.1307775645114296E-4,1.11162292689696E-4,3.9201085992963797E-6,0.22785288223907699,8575,"----+-------",0.458056020924966,"II","R",null,null,"PGK2","NM_138733","TSS200"]
[null,5,167719548,"cg15232798","PM2.5","12 months",-4.70173809382598E-4,1.02330380564782E-4,4.33445215928099E-6,0.25193623911256802,8580,"+--+-++-----",0.18431753029883199,"II","F",null,null,"WWC1;WWC1;WWC1","NM_001161662;NM_015238;NM_001161661","Body;Body;Body","chr5:167718523-167719688","Island",null,null,"5:167651074-167652234"]
[null,9,44745070,"cg14641231","PM10","365 days",-6.3498760199888103E-4,1.3850990360061901E-4,4.5524787555411204E-6,0.37902793415707697,8613,"------------",0.62064565507216196,"II","F","rs10908153",{"$nulls":4},"chr9:44743987-44744258","S_Shore"]
[null,2,32853039,"cg19757253","PM2.5-10","12 months",-1.39217712881455E-4,3.0423217190500099E-5,4.7387083832512E-6,0.377381886143138,8570,"-----+------",0.89428650834817303,"I","R",null,null,"TTC27","NM_017735","TSS200","chr2:32853007-32853270","Island",null,null,"2:32706435-32707015","2:32852291-32853612","Promoter_Associated"]
[null,20,57583188,"cg12787553","PM2.5-10","12 months",3.86371454148466E-4,8.4725346959274001E-5,5.1085030295165996E-6,0.377381886143138,8568,"++-+++++++++",0.34698648920917002,"II","F",null,"rs79270271","CTSZ","NM_001336","TSS1500","chr20:57581902-57582595","S_Shore"]
[null,19,43969886,"cg24950222","PM2.5-10","1 month",7.4551010815830903E-4,1.63956359106687E-4,5.4415141827564804E-6,0.269099499400832,8577,"++++++++++++",0.80191033180595594,"II","F",null,null,"LYPD3","NM_014400","TSS200","chr19:43967247-43968625","S_Shore"]
[null,4,38667430,"cg22453435","PM2.5","12 months",6.6523824276318105E-4,1.4632756729622299E-4,5.4616298630721197E-6,0.28217996165772202,8578,"++++++++-+++",0.27588772486561403,"II","F",null,null,"FLJ13197;KLF3","NR_026804;NM_016531","TSS1500;5'UTR","chr4:38664649-38666531","S_Shore"]
[null,17,17929033,"cg21187669","PM10","365 days",-7.2859938581780795E-4,1.6045274527467501E-4,5.6015400477502804E-6,0.37902793415707697,8618,"------------",0.65976167565354504,"II","R",null,null,"ATPAF2","NM_145691","Body",null,null,null,true,null,null,null,true]
[null,11,115088907,"cg16061656","PM2.5-10","1 month",-5.3321326573529005E-4,1.17602777521815E-4,5.7871731273552997E-6,0.269099499400832,8569,"---------+--",0.730473457427262,"II","R",null,null,"CADM1;CADM1","NM_001098517;NM_014333","Body;Body"]
[null,7,958244,"cg27572072","PM10","7 days",-2.2373159168825201E-4,4.9419347725577901E-5,5.9768531516605496E-6,0.64471750930929295,8618,"---+-+------",0.52857017959452202,"II","F","rs1534410",null,"ADAP1","NM_006869","Body","chr7:959724-959959","N_Shore"]
[null,19,46456210,"cg21632975","PM2.5","12 months",-7.0344750609589203E-4,1.55545577634684E-4,6.1127170555580402E-6,0.28423706418151001,8577,"---+--+-----",0.96171305533496698,"II","R",null,null,"NOVA2","NM_002516","Body","chr19:46456209-46456503","Island",null,true,"19:51147814-51148279",null,null,true]
[null,5,140700583,"cg15351446","PM10","28 days",-6.1081293152028698E-4,1.3547222394072299E-4,6.5204929793546499E-6,0.33871728191994299,8619,"------+-----",0.87523196582296403,"II","R",null,null,"TAF7","NM_005642","TSS1500","chr5:140699898-140700495","S_Shore",null,null,"5:140680760-140680833","5:140699328-140700860","Promoter_Associated",true]
[null,"X",19141251,"cg16641638","PM2.5-10","1 month",9.8118329245781909E-4,2.1763322467719599E-4,6.5310334848616499E-6,0.27608044120238801,8565,"+++-++++++++",0.71049154204267495,"I","R",null,null,"GPR64;GPR64;GPR64;GPR64","NM_005756;NM_001079859;NM_001079860;NM_001079858","TSS1500;TSS1500;TSS1500;TSS1500","chrX:19139937-19140629","S_Shore",null,null,"X:19049688-19051204"]
[null,5,67583609,"cg24797508","PM10","28 days",-5.7308949776070596E-4,1.27360967262379E-4,6.8041001904801896E-6,0.33871728191994299,8620,"------------",0.933028649824441,"II","R",null,null,"PIK3R1;PIK3R1","NM_181523;NM_181524","Body;TSS1500","chr5:67584213-67584451","N_Shore",null,null,null,"5:67583598-67584704","Promoter_Associated"]
[null,3,133393119,"cg24405999","PM2.5-10","12 months",-1.14904016151482E-3,2.5542174939261901E-4,6.8402571347223303E-6,0.377381886143138,8579,"---+--------",0.80102640477215803,"II","R",null,"rs79353799",null,null,null,"chr3:133393118-133393657","Island",null,null,"3:134875552-134876347"]
[null,6,28698008,"cg09294156","PM10","7 days",4.0459051964908703E-4,8.9994020546029497E-5,6.9325506976373098E-6,0.64471750930929295,8619,"++--++++-+++",0.10414643323353601,"I","R",{"$nulls":9},"6:28805742-28805992"]
[null,1,90231240,"cg12857520","PM2.5-10","12 months",7.5511478526390499E-4,1.6799254808513601E-4,6.9592756900197902E-6,0.377381886143138,8568,"+--+-++-++++",0.52239100615448497,"II","R",{"$nulls":5},"chr1:90228744-90229173","S_Shelf",null,null,null,"1:90231189-90231313","Unclassified_Cell_type_specific"]
[null,13,30088615,"cg09750646","PM2.5-10","12 months",2.4574717299920003E-4,5.4797725432512398E-5,7.3042754950897002E-6,0.377381886143138,8577,"-+++++++-+-+",0.11267906648901101,"II","F",null,null,"SLC7A1","NM_003045","3'UTR","chr13:30088558-30088772","Island",null,null,"13:28986598-28986848"]
[null,16,31235824,"cg10085057","PM10","28 days",2.6617824378775902E-4,5.94360556516339E-5,7.5205698365866998E-6,0.33871728191994299,8614,"++++++++++++",0.94545143560918399,"II","R",null,null,"TRIM72","NM_001008274","Body","chr16:31235525-31236104","Island",null,null,"16:31143042-31143605","16:31235797-31235920","Unclassified_Cell_type_specific"]
[null,2,32852828,"cg26189067","PM2.5-10","1 month",2.12497143455615E-4,4.7671473850092199E-5,8.2908474805093503E-6,0.289446461786667,8582,"+-+-+-++++++",0.11077417997192,"II","R",null,null,"TTC27","NM_017735","TSS1500","chr2:32853007-32853270","N_Shore",null,null,"2:32706200-32706369","2:32852291-32853612","Promoter_Associated"]
[null,1,38260988,"cg02851558","PM2.5-10","1 month",8.6903168611749998E-4,1.95095805778031E-4,8.4134300568210099E-6,0.289446461786667,8577,"-++-+++++-++",0.102121643165481,"II","F",null,null,"MANEAL;MANEAL;MANEAL","NM_001113482;NM_001031740;NM_152496","Body;Body;TSS200","chr1:38259095-38260427","S_Shore"]
[null,7,149809179,"cg21015808","PM10","365 days",1.20971142797624E-3,2.7158398947260898E-4,8.4174763855134897E-6,0.37902793415707697,8604,"+-+++-++++++",0.33122631944520398,"II","R",{"$nulls":9},"7:149439733-149440113"]
[null,19,15488783,"cg03654623","PM10","28 days",-5.1596983849312402E-4,1.1585281395697899E-4,8.4416046224228607E-6,0.33871728191994299,8620,"--++----+---",0.49403971764478599,"II","F","rs34428373",null,"AKAP8","NM_005858","Body","chr19:15489856-15491258","N_Shore",null,null,null,"19:15488773-15489081","Unclassified_Cell_type_specific"]
[null,7,142045032,"cg12155684","PM10","28 days",-5.3561435914492399E-4,1.2046628953627899E-4,8.7412227346203406E-6,0.33871728191994299,8620,"-++------+--",0.36627655409547799,"II","F","rs2855868"]
[null,20,30619137,"cg27531587","PM10","365 days",-1.0994527427016401E-3,2.4738252729445803E-4,8.8160959953206707E-6,0.37902793415707697,8587,"+--+-+---+--",0.21689237019509,"II","F",null,null,"C20orf160","NM_080625","3'UTR","chr20:30618793-30619138","Island",null,true,"20:30082455-30082986","20:30618596-30620114","Unclassified"]
[null,5,33936752,"cg02341815","PM2.5","1 month",-3.8308535504908803E-4,8.6378329682150807E-5,9.2084842858210202E-6,0.465632864564761,8562,"-+----------",0.942278457886917,"II","R",null,null,"RXFP3;RXFP3","NM_016568;NM_016568","1stExon;5'UTR","chr5:33936168-33938309","Island",null,true,"5:33971926-33974929",null,null,true]
[null,13,19919758,"cg03941975","PM10","1 month",-3.2598438296004901E-4,7.37439857752654E-5,9.8478385791092006E-6,0.91586506676930002,8576,"---------+--",0.705694689901044,"II","F",null,null,"LOC100101938","NR_027248","TSS1500","chr13:19918585-19919221","S_Shore"]
[null,2,27166550,"cg18990157","PM10","1 month",-5.0885754881421796E-4,1.15113623900064E-4,9.8481597225044193E-6,0.91586506676930002,8575,"----+----+--",0.34397804841646501,"II","R",null,"rs34064589","DPYSL5","NM_020134","Body",null,null,null,true]
[null,"Abbreviations: B37, build 37; Chr, chromosome; CpG, cytosine-phosphate-guanine site; DHS, DNase 1 hypersensitivity site; F, forward; FDR, false discovery rate;HMM, Hiden Markov Model; PM, particulate matter; R, reverse; SE, standard error; SNP, single nucleotide polymorphism; UCSC, University of California Santa Cruz"]