The PDF file includes:

• Fig. S1. Incubated cocaine craving during prolonged abstinence following extended-access cocaine self-administration.
• Fig. S2. Experimental timeline and tissue collection.
• Fig. S3. Custom HSV vectors made to manipulate INO80.
• Fig. S4. Cue-induced food seeking and locomotor activity following food self-administration.
• Fig. S5. Custom HSV vectors made to manipulate TRIM3.
• Fig. S6. Expression of TRIM3 and synaptic substrates during abstinence following extended-access self-administration.
• Fig. S7. Similar cocaine-seeking behavior in rats that received intra-NAc injections of HSV-TRIM3 or HSV-NLS-TRIM3.
• Fig. S8. Schematic of INO80 signaling in the NAc.
• Table S1. Primer list for qPCR.
• Table S2. Primer list for ChIP.
• Legend for data S1

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Other Supplementary Material for this manuscript includes the following:

• Data S1 (Microsoft Excel format). INO80 ChIP-seq data tables.