Table S4,Top 10 GO terms and KEGG pathways enriched with mESCs essential genes,,,
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GO Term,Description,p-value,FDR corrected p-value,Enrichment (Odds ratio)
GO:0022613,Ribonucleoprotein complex biogenesis,6.21E-82,2.91E-79,7.18
GO:0006412,Translation,8.97E-137,8.98E-134,6.48
GO:0006364,rRNA processing,1.60E-88,8.00E-86,6.36
GO:0034470,ncRNA processing,3.15E-104,2.15E-101,5.22
GO:0022618,Ribonucleoprotein complex assembly,4.10E-52,1.34E-49,4.88
GO:0008380,RNA splicing,3.40E-69,1.38E-66,4.52
GO:0006396,RNA processing,2.39E-172,3.59E-169,4.51
GO:0051276,Chromosome organization,9.33E-42,2.46E-39,3.68
GO:0033044,Regulation of chromosome organization,2.02E-44,5.72E-42,3.56
GO:0006281,DNA repair,3.06E-53,1.07E-50,3.52
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KEGG ID,Description,p-value,FDR corrected p-value,Enrichment (Odds ratio)
mmu03010,Ribosome,4.39E-54,1.07E-51,110.3019442
mmu03040,Spliceosome,2.43E-48,2.95E-46,26.47126821
mmu03013,RNA transport,2.12E-40,1.72E-38,13.99637647
mmu00190,Oxidative phosphorylation,2.35E-29,1.43E-27,12.99147505
mmu03030,DNA replication,1.30E-23,6.34E-22,85.12772384
mmu05016,Huntington disease,2.13E-23,8.63E-22,7.594372566
mmu04110,Cell cycle,1.33E-22,4.62E-21,8.45083549
mmu03008,Ribosome biogenesis in eukaryotes,6.07E-21,1.64E-19,33.85144861
mmu03050,Proteasome,1.27E-19,3.09E-18,26.35601829
mmu03020,RNA polymerase,1.87E-19,4.13E-18,98.5641261