"","E1","E2","E12","zscore","zscoreD12D1","zscoreD12D2","VarEta1","VarEta2","sdtotal","CovD12D12p","CovD12D1p2","CovD1D12","CovD1D12.1","vartotD12D1","vartotD12D2","pvalue","pvalueD12D1","pvalueD12D2","pvalueTotal","mysdtotal","pathway_name","metric","group1","group2","pvaluadj" "HALLMARK_PANCREAS_BETA_CELLS",0.0711541191757019,0.0823560346341179,0.0916293692413095,-4.60948757823418,10.0724919543304,3.5037062163086,2.7798445003134e-06,3.02596295134851e-06,0.00240952432062055,7.65477887415614e-05,0.000247790123462734,4.00247274963527e-05,4.00247274963527e-05,4.03223080298435e-06,6.90513475114461e-06,4.03662649239855e-06,0,0.000458831245452762,0,0.00203905178436263,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN25",7.01192430585037e-06 "HALLMARK_MYOGENESIS",0.0517935644305804,0.0647154101784875,0.0741956557842517,-6.61555825796338,10.3467354089492,3.76415676324428,1.85540433717388e-06,1.85978511114883e-06,0.00192748267134175,2.62860388279534e-05,0.000398564743189312,1.50398766485624e-05,1.50398766485624e-05,4.58781475113017e-06,6.24313236056959e-06,3.70152797302126e-11,0,0.000167112030015959,0,0.0020860981495896,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN25",9.82617809542437e-11 "HALLMARK_IL2_STAT5_SIGNALING",0.047849951194823,0.0519399686119973,0.0636402427917841,-2.28212819904233,10.4688691576348,5.50722117998251,1.323341741666e-06,1.78861908661645e-06,0.00176407506310884,3.59427080298498e-05,0.000186673068729346,2.79356472303147e-05,2.79356472303147e-05,2.17499662347089e-06,4.41364127405598e-06,0.0224817725916169,0,3.64542134256851e-08,0,0.00155141418613285,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN25",0.0291816385957411 "HALLMARK_ESTROGEN_RESPONSE_EARLY",0.0549660610348763,0.0627816052544171,0.0788690735125521,-3.74926224378246,12.1211208590941,5.68460633097936,1.99671460451586e-06,2.24865590309669e-06,0.00206042969004345,0.000111267941071258,0.000369457290418708,6.15927484086008e-05,6.15927484086008e-05,3.78883675884196e-06,7.90893220150287e-06,0.000177355550003311,0,1.31114326062942e-08,0,0.00217522013783028,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN25",0.000269122744263088 "HALLMARK_BILE_ACID_METABOLISM",0.054052772674304,0.0597841507040811,0.0710561145595794,-2.91161848281553,9.58349923998376,4.80177059195075,1.8903230215468e-06,1.88447593338861e-06,0.00194288418464287,3.3705873789096e-05,0.000227565471727718,2.73501635994558e-05,2.73501635994558e-05,3.04789580621157e-06,5.41056792529559e-06,0.00359561512051365,0,1.57268806377786e-06,0,0.00162092360439531,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN25",0.00496296171563856 "HALLMARK_MITOTIC_SPINDLE",0.0989643076637039,0.0896302041009672,0.111605524959553,2.36343973296456,6.77743701166777,5.11942347257666,3.55807105951202e-06,1.19394710012821e-05,0.00393669176603834,0.000488669657998141,0.000279630111840304,0.000201474752506325,0.000201474752506325,3.37893899586615e-06,1.83258842664993e-05,0.0181061713359345,1.22326593299249e-11,3.06471097832883e-07,3.66979779897747e-11,0.00345806132196706,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN25",0.0236062721630366 "HALLMARK_INFLAMMATORY_RESPONSE",0.0412617631535964,0.0513563505526463,0.0595427088058154,-6.03218499685115,10.9328289223813,4.2346914731558,1.46075757508481e-06,1.23969253897897e-06,0.00164330463215552,3.00819800854355e-05,0.000258530033276408,3.18146282452395e-05,3.18146282452395e-05,2.69596808951429e-06,3.63712774940561e-06,1.6175745187752e-09,0,2.28865707685433e-05,0,0.00188666985768413,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN25",3.78184420294162e-09 "HALLMARK_ESTROGEN_RESPONSE_LATE",0.0676585006223306,0.0689556637412176,0.0886427848196205,-0.539956780875984,10.911481648709,6.31024482356486,2.29619863254597e-06,3.3750686159613e-06,0.00238144226226614,0.000136619908517049,0.000363738193282665,8.35820917768505e-05,8.35820917768505e-05,3.5984594858757e-06,9.6335666283361e-06,0.589226838243129,0,2.78594480818128e-10,0,0.00224426510643691,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN25",0.628223718743354 "HALLMARK_ADIPOGENESIS",0.0439900925189429,0.0553894195645162,0.0651074968284837,-7.34026417713411,11.4949722035896,4.23115940853095,1.00514681803277e-06,1.30661850444153e-06,0.00152044905290322,1.64168409574035e-05,0.000345310268231692,1.48546571198454e-05,1.48546571198454e-05,3.27493349311229e-06,5.17523632024692e-06,2.1316282072803e-13,0,2.32489827680649e-05,0,0.00184758939005516,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN25",6.92484743580562e-13 "HALLMARK_P53_PATHWAY",0.0601869212454875,0.0705628354994589,0.0833094898801042,-4.82089268504316,11.2237501011814,4.55629956773862,1.89127302894954e-06,2.64103915691134e-06,0.00212892277592704,4.67858918374682e-05,0.00039981267544975,3.7272597770123e-05,3.7272597770123e-05,4.1442032882459e-06,7.72650523122918e-06,1.42917229251083e-06,0,5.20626711497663e-06,0,0.00212832049635792,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN25",2.5976918330645e-06 "HALLMARK_HEME_METABOLISM",0.0512313830199301,0.0588376147373609,0.0693266063794452,-3.74028192639866,9.84200674624597,4.53841944473664,1.85146552307123e-06,2.18405733866403e-06,0.00200886108572376,2.47383128975541e-05,0.000284704641610169,3.05370710266518e-05,3.05370710266518e-05,3.28034151898864e-06,5.24143830002611e-06,0.000183813964979018,0,5.66774389088032e-06,0,0.00189588046736004,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN25",0.000278563431463048 "HALLMARK_CHOLESTEROL_HOMEOSTASIS",0.0494624007780606,0.0614800746083769,0.0738854518858608,-6.52543662502995,12.2205810377875,4.35228075873623,1.08476188910935e-06,2.20697123746182e-06,0.0018143134036244,3.50797641913226e-05,0.000433439767728234,2.36558906891162e-05,2.36558906891162e-05,3.89407417451573e-06,8.02430365012269e-06,6.78037626045125e-11,0,1.34728574905374e-05,0,0.0020145473087593,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN25",1.76020363847476e-10 "HALLMARK_NOTCH_SIGNALING",0.0414518615522329,0.0476969159176227,0.0608530289222092,-2.64236127804975,9.11391249494819,5.87013501778478,3.53267187667541e-06,1.95316249307428e-06,0.00234218581025283,5.56965218143496e-05,0.00021713744804966,3.91786790423644e-05,3.91786790423644e-05,4.43154206235601e-06,4.92295178535623e-06,0.00823301837666657,0,4.35440372648088e-09,0,0.00191710541732409,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN25",0.0109649259467269 "HALLMARK_ALLOGRAFT_REJECTION",0.0422240911173675,0.0451671079718023,0.0536163080052655,-1.76275377448484,8.20215469592652,5.12202144612607,1.42421552260244e-06,1.26320306650619e-06,0.00163933480079837,2.17443194209248e-05,0.000125952867997165,2.41623529767597e-05,2.41623529767597e-05,1.82912592379987e-06,2.6211244154615e-06,0.0779420268488005,2.22044604925031e-16,3.02277501029735e-07,6.66133814775094e-16,0.0014211063764639,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN25",0.0960794796375151 "HALLMARK_INTERFERON_GAMMA_RESPONSE",0.0391233728413272,0.0554741861517145,0.0668582455505596,-10.39520040019,12.6392658122237,4.34379228569353,1.17568157727159e-06,1.19839414428804e-06,0.0015408035960367,1.85800504250927e-05,0.000499895671396432,1.1333833478512e-05,1.1333833478512e-05,4.71513712140701e-06,6.76840992036487e-06,0,0,1.40043936840417e-05,0,0.00219914840572074,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN25",0 "HALLMARK_ANDROGEN_RESPONSE",0.0489756766015759,0.0563807528772179,0.0707161917684306,-4.32338475028185,11.8637118996332,5.54005928355579,1.21150725634067e-06,1.62216301510025e-06,0.00168335090561681,7.16193669102654e-05,0.00034161401551163,3.55003234426914e-05,3.55003234426914e-05,3.25813753205075e-06,6.59565646819366e-06,1.53653422443334e-05,0,3.0236926962246e-08,0,0.00188960136350911,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN25",2.53076225200785e-05 "HALLMARK_TNFA_SIGNALING_VIA_NFKB",0.0500721696870788,0.0641557580292891,0.07610913308547,-6.88776967582193,11.8312268723513,4.46604869315778,2.02080087060055e-06,2.06009559094493e-06,0.00202012288278349,3.85679777123067e-05,0.000438788917534297,2.89714822694878e-05,2.89714822694878e-05,4.74307395012108e-06,7.06364713071902e-06,5.6674664961065e-12,0,7.96774824829427e-06,0,0.00224829729127972,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN25",1.62956982870935e-11 "HALLMARK_PEROXISOME",0.048178841278776,0.0539081472017112,0.0662526885844904,-3.33013864833868,11.4120504561604,5.11534447558063,8.93880950684247e-07,1.96603510242372e-06,0.00169112863292772,2.77537078009499e-05,0.000245240207033909,1.7990175574403e-05,1.7990175574403e-05,2.40826750304003e-06,5.72371548511191e-06,0.000868027495766865,0,3.13168893262272e-07,0,0.00150409721579246,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN25",0.00125405446562879 "HALLMARK_INTERFERON_ALPHA_RESPONSE",0.0531607932596956,0.0754280213897922,0.0903148733243285,-10.4850184102404,12.2999102019378,4.11587854911056,2.20933565659613e-06,2.20084483726825e-06,0.0021000429742899,3.12663840918385e-05,0.000985374381246271,2.66596994223612e-05,2.66596994223612e-05,9.02450143231035e-06,1.29821955145981e-05,0,0,3.85707379653155e-05,0,0.00307347261094128,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN25",0 "HALLMARK_TGF_BETA_SIGNALING",0.0496919984228251,0.061045672474625,0.0695443864832769,-5.40416923758324,9.84490011597149,3.39401338167175,2.01612914894066e-06,2.29769434694243e-06,0.00207697460164613,4.09977842309294e-05,0.000384106264151218,4.2318593204587e-05,4.2318593204587e-05,3.96633245973258e-06,6.1701701961965e-06,6.51094489434456e-08,0,0.000688763269165227,0,0.0022340577642929,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN25",1.3386138454107e-07 "HALLMARK_FATTY_ACID_METABOLISM",0.0428609711256576,0.0562917719677744,0.0674187387087552,-8.44267254888924,11.9116933471056,4.14632544779457,1.19709052420127e-06,1.23362848770465e-06,0.00155907633293111,2.28797199398958e-05,0.000438897608661849,1.69912053286504e-05,1.69912053286504e-05,4.15040937433177e-06,7.10156368397334e-06,0,0,3.37853521255038e-05,0,0.00195507337090654,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN25",0 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE",0.0686224407126257,0.0829681281229929,0.100388758770955,-5.87688446551157,11.4618471854595,4.64015139191827,2.17793934535151e-06,3.68071812420573e-06,0.00242046637439094,6.37884309791885e-05,0.000794709708935347,3.44092274504344e-05,3.44092274504344e-05,7.58111968057151e-06,1.39949469390548e-05,4.180597645842e-09,0,3.48154027229874e-06,0,0.00268482986940196,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN25",9.38240998379807e-09 "HALLMARK_MTORC1_SIGNALING",0.0588455096654909,0.0617293402259869,0.0756624138817756,-1.39573491748121,10.4615986421597,5.31714852831669,1.18647790972841e-06,2.98259520289231e-06,0.00204183082370228,5.36634897463544e-05,0.000274772548240965,3.97708230949383e-05,3.97708230949383e-05,2.48402072427316e-06,6.7665135587323e-06,0.162794335325751,0,1.05406024797361e-07,0,0.00183410502418977,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN25",0.191064010322438 "HALLMARK_UV_RESPONSE_UP",0.0548457837954904,0.0600502046091224,0.0726515784236398,-2.72984565890948,10.6480114358175,5.16300208711335,1.18522937821449e-06,2.34947105911841e-06,0.00188007990184803,4.19680386280806e-05,0.000293655612507652,3.43051936676463e-05,3.43051936676463e-05,2.69631248702982e-06,5.8570492222626e-06,0.00633639831776933,0,2.43020429335772e-07,0,0.00185645532207395,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN25",0.00851611933908198 "HALLMARK_ANGIOGENESIS",0.0645841693991745,0.0790893367035214,0.0986846380343182,-6.25541895888277,12.7769552271757,5.77631412356934,2.87379682223617e-06,2.40311210649413e-06,0.00229715235209385,0.000112307573960269,0.000649482906167835,5.24941150351369e-05,5.24941150351369e-05,7.02304928040992e-06,1.14080644966671e-05,3.96450205997212e-10,0,7.63547647331109e-09,0,0.00263709777788924,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN25",9.71303004693169e-10 "HALLMARK_MYC_TARGETS_V1",0.0871747345320246,0.0983640790609649,0.116898769330705,-3.05027404554131,10.1578068198475,4.17337772727119,4.4915514651811e-06,8.86493174604759e-06,0.00365465226953655,0.000172660477454309,0.000797024221306217,0.000112349510798256,0.000112349510798256,8.46279651709383e-06,1.9624012909291e-05,0.00228632643785165,0,3.00116758014113e-05,0,0.00328056707535257,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN25",0.00319325402721323 "HALLMARK_DNA_REPAIR",0.0702076500637652,0.0821183922126577,0.0989500031477643,-4.61823053370401,11.0282507168955,4.51626959385698,1.85066640922686e-06,4.70093825397352e-06,0.0025596102561133,8.50801508729942e-05,0.000753900425301704,4.87192043516207e-05,4.87192043516207e-05,6.69252708229462e-06,1.37896611246472e-05,3.8702614519881e-06,0,6.29385277406413e-06,0,0.0027687898311248,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN25",6.74285550746371e-06 "HALLMARK_KRAS_SIGNALING_UP",0.0562201964591611,0.0666536685062148,0.080088033044982,-4.81910568116,10.6095145951208,5.00339135225345,2.61800711560302e-06,1.96931514589216e-06,0.00214180350674267,5.21766701040869e-05,0.000430880622803891,4.35833747059857e-05,4.35833747059857e-05,4.96098537488255e-06,7.10950272036305e-06,1.442031582366e-06,0,5.63304198397674e-07,0,0.00224860452092047,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN25",2.61298789038893e-06 "HALLMARK_HYPOXIA",0.0474225779462575,0.05385310290652,0.0650374473647556,-3.56784970017532,10.9009697628571,5.21472324572789,1.44545181290757e-06,1.70302487691533e-06,0.00177439473900902,4.92116326865303e-05,0.00023797834218334,3.71626745672557e-05,3.71626745672557e-05,2.51113055052023e-06,4.5000074917099e-06,0.000359922849958672,0,1.84091874411152e-07,0,0.00181219369338426,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN25",0.000533084724875816 "HALLMARK_SPERMATOGENESIS",0.0637002379348352,0.0740759952748093,0.0899449935655188,-4.64216527668675,11.093531189993,4.8178740698407,1.96492996342039e-06,2.93079378637857e-06,0.00221262824482536,6.46872072455583e-05,0.000554314110083762,3.73373331748403e-05,3.73373331748403e-05,5.49687295920488e-06,1.07489607599187e-05,3.44776891902931e-06,0,1.45095895032199e-06,0,0.00228057467732065,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN25",6.0335956083013e-06 "HALLMARK_OXIDATIVE_PHOSPHORYLATION",0.0742550278774566,0.100467515105513,0.114441889726897,-9.21082087830661,11.1548427512244,3.26873164788493,3.3168923042095e-06,4.68189121288684e-06,0.00282821207074299,6.61603026971547e-05,0.00142294385109437,5.35306922438156e-05,5.35306922438156e-05,1.2879001508471e-05,1.81770553589476e-05,0,0,0.00108030706680862,0,0.00391166887836023,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN25",0 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION",0.0487361008537033,0.0633505536886542,0.0761873787916127,-7.76980921729964,12.2062188759215,4.49548193376009,1.64744956827069e-06,1.79044111685815e-06,0.0018541549787245,3.10717464907205e-05,0.000498042583289054,2.19909418104672e-05,2.19909418104672e-05,4.95781368766374e-06,8.05385032112484e-06,7.7715611723761e-15,0,6.94125519085098e-06,0,0.00219645201234766,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN25",2.85604873084822e-14 "HALLMARK_MYC_TARGETS_V2",0.0699540341799674,0.0873711284740008,0.102472567161599,-6.40174904926583,11.0140031053585,3.74385293766502,2.7904261257897e-06,4.51165967401484e-06,0.00270223718422431,9.01439771405742e-05,0.000928640812766654,6.11582154249352e-05,6.11582154249352e-05,8.61708941237835e-06,1.61704320593985e-05,1.53606904973458e-10,0,0.000181219746451022,0,0.00307205160473368,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN25",3.86813105457787e-10 "HALLMARK_E2F_TARGETS",0.0818839205213523,0.0779605614542278,0.0971333536585168,1.1925393647139,8.6723724645614,5.04591640089615,2.70900305564458e-06,8.01457033206908e-06,0.0032746867617703,0.000341255208972817,0.000304374660323195,0.000154911729028739,0.000154911729028739,2.99194355075122e-06,1.43374545081286e-05,0.233049825170498,0,4.51352740515887e-07,0,0.00295169099820301,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN25",0.266342657337713 "HALLMARK_IL6_JAK_STAT3_SIGNALING",0.0391278087622696,0.043709061400224,0.0521802004982534,-2.84074880179181,8.89847571775437,5.00327485563277,1.35454998570499e-06,1.14622524148776e-06,0.00158138395944589,2.73530229450616e-05,0.000152473719598663,2.22689110854113e-05,2.22689110854113e-05,2.05153769768104e-06,2.76665152700954e-06,0.00450077492410306,0,5.63644867002111e-07,0,0.0014910135528827,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN25",0.00612605475780694 "HALLMARK_PROTEIN_SECRETION",0.0615663822325598,0.080298300740067,0.0951674896195713,-7.52901463671729,11.5996401878739,4.01169283825312,2.75297586250454e-06,3.33698975349588e-06,0.0024677855692909,4.12981516725204e-05,0.000849265964410536,3.83139009313789e-05,3.83139009313789e-05,8.29108548096796e-06,1.36378639183632e-05,5.10702591327572e-14,0,6.02849047013354e-05,0,0.0028778009016043,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN25",1.74082970261225e-13 "HALLMARK_UV_RESPONSE_DN",0.047570105753559,0.0608241915193997,0.0748083332504974,-6.91633155194744,12.3997739042964,4.66994981287419,1.74473847242352e-06,1.82764432923542e-06,0.00189007481377297,4.91967798266421e-05,0.000475889580521856,3.22767903508793e-05,3.22767903508793e-05,4.72536481260255e-06,8.86700077465282e-06,4.6349590832051e-12,0,3.01273329239571e-06,0,0.0021074001603297,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN25",1.34918610936861e-11 "HALLMARK_APOPTOSIS",0.0519763665553804,0.063332961006391,0.0766632537180998,-6.005473431703,11.7649427784504,4.78916661007946,1.51862488827442e-06,1.95740989523637e-06,0.00186441271812622,3.77536089119918e-05,0.000433008667979708,2.50830122206164e-05,2.50830122206164e-05,4.30304400134029e-06,7.64746244891206e-06,1.90774396280347e-09,0,1.67475389734051e-06,0,0.00204132815758217,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN25",4.43380810327446e-09 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY",0.0421074373486542,0.0528087342495026,0.062100015976678,-5.91850629816074,10.9958660938048,4.15496131146461,1.50901581340529e-06,1.66023769677849e-06,0.00178023973390771,2.79139180885146e-05,0.000279834869028667,2.0681653268058e-05,2.0681653268058e-05,3.20581648164598e-06,4.90054441591318e-06,3.24878568491727e-09,0,3.25342587790267e-05,0,0.00183157685939858,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN25",7.34725377973597e-09 "HALLMARK_COMPLEMENT",0.0416732509125227,0.052771750381255,0.0623698107927162,-7.28897048428719,11.5371977162547,4.39005160081449,1.16051034459902e-06,1.05793118689147e-06,0.00148944336296836,2.07796161086999e-05,0.000318610214218014,1.98993574618079e-05,1.98993574618079e-05,3.11807126941558e-06,4.67999792688121e-06,3.12416759129519e-13,0,1.13323766297579e-05,0,0.00182250054714367,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN25",9.98375295479115e-13 "HALLMARK_APICAL_JUNCTION",0.0467409813713996,0.0567694944253306,0.0687650084109246,-5.6975759500067,11.4425511245362,4.77080751030456,1.37636455929085e-06,1.62171696671117e-06,0.00173149690326088,3.16881239541544e-05,0.00032748004810381,1.54677079495292e-05,1.54677079495292e-05,3.60465474497542e-06,6.22199188912523e-06,1.21522851781464e-08,0,1.83488825888922e-06,0,0.00175927332318816,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN25",2.65140767523194e-08 "HALLMARK_GLYCOLYSIS",0.0650122308992198,0.0652324037652092,0.08097678632442,-0.100676362141406,9.45497422155144,6.12898850962307,1.65978394950701e-06,3.02290969217626e-06,0.00216395324387642,6.17332725377394e-05,0.000244307450146392,4.10533820204137e-05,4.10533820204137e-05,2.75097205065894e-06,6.49893200159029e-06,0.919807376295594,0,8.84395223721413e-10,0,0.00183646090604161,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN25",0.936790645927455 "HALLMARK_PI3K_AKT_MTOR_SIGNALING",0.0461640483531542,0.0597711886736688,0.0683493248045487,-8.02244554116441,10.9400217523874,3.43781872132155,1.21044204211821e-06,1.56642752071714e-06,0.00166639417990923,1.70532495984864e-05,0.000428938965949244,1.82317543384672e-05,1.82317543384672e-05,4.01238076033105e-06,6.12615493100371e-06,1.11022302462516e-15,0,0.000586420140658017,0,0.00209352974955092,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN25",4.42583822698029e-15 "HALLMARK_G2M_CHECKPOINT",0.0959076730001498,0.0839662119372533,0.105589431700078,3.0486127202622,6.09364342087402,5.25204055333652,3.41952979974642e-06,1.18234749333712e-05,0.00390422908307358,0.000505248928784677,0.000215513412844533,0.000217433352241036,0.000217433352241036,2.42437827811454e-06,1.68505807676418e-05,0.00229900646452696,1.10369358097273e-09,1.50423331346516e-07,3.31108074291819e-09,0.00352867523365452,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN25",0.00320715492560345 "HALLMARK_APICAL_SURFACE",0.0565427754443983,0.0564786425689986,0.071065466987022,0.0325110743803353,8.50178330382115,6.13435374549427,1.34281053446699e-06,2.44852590171119e-06,0.00194713544371679,0.000183345087970991,0.000220255162822427,5.17365901604129e-05,5.17365901604129e-05,2.81792526033433e-06,5.55436549608414e-06,0.974064484620711,0,8.55060688920162e-10,0,0.00212836172816333,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN25",0.977388936786652 "HALLMARK_XENOBIOTIC_METABOLISM",0.0537185284077117,0.0610165996631119,0.0712233743343584,-3.90000447343236,10.7040830551416,4.52285461818503,1.42008825369807e-06,1.98166860776298e-06,0.00184438522588451,2.98108005846107e-05,0.000240895543896326,2.99741460818817e-05,2.99741460818817e-05,2.57434630934492e-06,4.99274344279644e-06,9.61909107071168e-05,0,6.10111481935682e-06,0,0.00173122957099605,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN25",0.000147869949008587 "HALLMARK_WNT_BETA_CATENIN_SIGNALING",0.055543579074023,0.0712722312307369,0.08622046561617,-5.94103942563528,10.8915858658922,4.53439548257079,3.97286748019251e-06,2.93616620421422e-06,0.00262850407730457,0.000119284390296378,0.000619827731433879,5.66099296802286e-05,5.66099296802286e-05,7.83305236248756e-06,1.07677841965907e-05,2.83220491503755e-09,0,5.77686988334492e-06,0,0.00280621553874592,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN25",6.49253992219134e-09 "HALLMARK_KRAS_SIGNALING_DN",0.0656416687845207,0.0792131736141425,0.0931253460980899,-5.93447776548325,10.8403600301168,4.62095652190037,2.55639387131979e-06,2.57347737459118e-06,0.00226492190724338,5.86841364778375e-05,0.000605944307908966,4.09408998580021e-05,4.09408998580021e-05,6.32779872587184e-06,8.96413034650569e-06,2.94782265264359e-09,0,3.81974827012854e-06,0,0.00261308253194339,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN25",6.73133871749295e-09 "HALLMARK_COAGULATION",0.0531330741087067,0.0630387859640964,0.0762027991826429,-5.14246303954857,11.17151618571,4.98817761572148,1.92995744677694e-06,1.68051339902039e-06,0.0019001239027488,3.37310892264686e-05,0.000372771802912872,2.75921364303634e-05,2.75921364303634e-05,4.16442616945679e-06,6.86454583857405e-06,2.71159799281051e-07,0,6.09515189653465e-07,0,0.00191550056232544,"HALLMARK_COAGULATION","kendall_tau","HN18","HN25",5.3147320659086e-07 "HALLMARK_HEDGEHOG_SIGNALING",0.0580313852159569,0.0639525881051557,0.0717978534697461,-2.88828636588262,8.49978381236243,3.69640904193847,1.45941790108715e-06,2.64338849394745e-06,0.00202553854444555,5.98738016893757e-05,0.000208323256743766,3.21493093264433e-05,3.21493093264433e-05,2.52318738784247e-06,4.40458958489047e-06,0.00387347050483999,0,0.000218670553536304,0,0.00191391347684479,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN25",0.00531528741387612 "CELL_CYCLE",0.0578870825417588,0.0604739460591778,0.0704865930089811,-1.31474302379904,8.63080071970923,4.54171390815964,1.31341517074861e-06,2.4579601916862e-06,0.00194200292544445,7.61622198243413e-05,0.000185791177713299,4.24489028925676e-05,4.24489028925676e-05,2.03110655592491e-06,4.76024608106815e-06,0.188596281820802,0,5.57987299276697e-06,0,0.00181322309956259,"CELL_CYCLE","kendall_tau","HN18","HN25",0.217867610433461 "PEMT",0.0815780726068496,0.100327446839623,0.118156501044561,-6.36427570623255,11.6708792639634,4.24856506597796,3.93465860359663e-06,4.64445922243364e-06,0.00292901311469073,0.00013855125316775,0.00096873814886636,8.50754446459507e-05,8.50754446459507e-05,9.72297259269788e-06,1.75105152645357e-05,1.96213489900288e-10,0,2.15144161239689e-05,0,0.00327098112008406,"PEMT","kendall_tau","HN18","HN25",4.89908841024922e-10 "EPI_DIFF1",0.0801683328661746,0.0998928914325615,0.119102043893089,-5.20483789226324,11.3237582180128,4.43888705395898,8.02719809314447e-06,6.23431404593445e-06,0.00377644172986674,0.000307659744875417,0.00114016503454744,0.000245420727349044,0.000245420727349044,1.17214412056637e-05,1.86270003077251e-05,1.94166027700504e-07,0,9.04252510958159e-06,0,0.00431460198040218,"EPI_DIFF1","kendall_tau","HN18","HN25",3.83763442984526e-07 "EPI_DIFF2",0.0857198812378668,0.0956115639619175,0.116337791561672,-3.20155337429319,10.5454718486872,4.98263841858588,3.54320841508303e-06,5.90273515618293e-06,0.00307342538078704,0.000107180518840778,0.000835468242023596,7.74825257031601e-05,7.74825257031601e-05,8.32983472804006e-06,1.72030148791765e-05,0.00136688749444502,0,6.27230915650756e-07,0,0.00295069944924765,"EPI_DIFF2","kendall_tau","HN18","HN25",0.00193436786217491 "STRESS",0.0672910861296235,0.0913189203480579,0.108088595823444,-8.62210326439824,12.2846710741579,3.92336699270982,4.14499835610827e-06,3.52109869916122e-06,0.00276877175933111,7.87333508372959e-05,0.00108973582418673,6.68721214327405e-05,6.68721214327405e-05,1.0929104289498e-05,1.81697013649575e-05,0,0,8.73199819706461e-05,0,0.00331156031078183,"STRESS","kendall_tau","HN18","HN25",0 "HYPOXIA",0.0665299936038447,0.0786452905262723,0.0962304719005907,-4.7688066370879,11.7730293778611,5.14808275897707,2.8492370719842e-06,3.50505624469379e-06,0.00252077236510519,9.93736480130458e-05,0.000602066477898297,6.25724879452184e-05,6.25724879452184e-05,6.26429689079405e-06,1.15681677512823e-05,1.85320429135771e-06,0,2.63162388325355e-07,0,0.00262253853251547,"HYPOXIA","kendall_tau","HN18","HN25",3.31715106032979e-06 "HALLMARK_PANCREAS_BETA_CELLS1",0.0711541191757019,0.0666050356191201,0.0840024380517338,1.46809443668972,8.36365863943305,6.35477314263894,2.7798445003134e-06,6.72167220847496e-06,0.00308245303431997,0.000230467044729291,7.02152456767552e-05,0.000110426747891003,0.000110426747891003,2.25993485941608e-06,7.39494959289526e-06,0.142078572562678,0,2.08734363127405e-10,0,0.00289171750021015,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN16",0.168262236992658 "HALLMARK_MYOGENESIS1",0.0517935644305804,0.0476061393486547,0.0624516066246727,1.74872980813414,8.96674110851163,8.32578460922969,1.85540433717388e-06,3.7784766480423e-06,0.00237357978277879,0.000123663374440874,5.03497292888518e-05,7.47267240133629e-05,7.47267240133629e-05,1.31281601382844e-06,3.07934312781111e-06,0.0803377349441452,0,0,0,0.00237886010758533,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN16",0.0987222322824606 "HALLMARK_IL2_STAT5_SIGNALING1",0.047849951194823,0.0392525605896687,0.0554698163857517,4.41143296584869,6.25595599206771,10.4809284360503,1.323341741666e-06,2.37482431639835e-06,0.00192306163657444,0.000119075922711348,3.41329163944435e-05,4.44871772224474e-05,4.44871772224474e-05,1.38356714172161e-06,2.29417131205145e-06,1.02688746945745e-05,3.95088184390602e-10,0,0,0.00196114270668542,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN16",1.72517094868851e-05 "HALLMARK_ESTROGEN_RESPONSE_EARLY1",0.0549660610348763,0.0438919749653701,0.0715109981497022,5.14085171790901,11.0323810000201,13.2373246255208,1.99671460451586e-06,2.54358086016867e-06,0.00213079690836188,0.000277346849362928,5.93472720597241e-05,9.32620072298359e-05,9.32620072298359e-05,2.14901182180518e-06,4.25327587832976e-06,2.73495837532778e-07,0,0,0,0.0026349302923349,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN16",5.35159908383605e-07 "HALLMARK_BILE_ACID_METABOLISM1",0.054052772674304,0.0458022264863311,0.0611952684575924,3.51557526058615,5.53735567494979,8.20336446127504,1.8903230215468e-06,3.51740645064396e-06,0.00232545253062512,0.00019563422342359,3.93505416494302e-05,7.97358170498376e-05,7.97358170498376e-05,1.56377711126926e-06,3.42099082363891e-06,0.000438802370309022,3.07072549610155e-08,2.22044604925031e-16,6.66133814775094e-16,0.00244507938892124,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN16",0.000645846792845318 "HALLMARK_MITOTIC_SPINDLE1",0.0989643076637039,0.0712586271397228,0.0982779693234786,7.60313283826125,-0.316786984790538,10.2167050606337,3.55807105951202e-06,9.62053501993632e-06,0.00363023498956312,0.000408685992979965,0.000145862568194361,0.000137818531860706,0.000137818531860706,4.59398675371198e-06,6.89403546950702e-06,2.88657986402541e-14,0.751405240610278,0,0,0.00382185756040166,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN16",1.00136221831678e-13 "HALLMARK_INFLAMMATORY_RESPONSE1",0.0412617631535964,0.0377023217422396,0.0505302792849682,1.8022754470426,8.54033783888957,9.30002408520055,1.46075757508481e-06,2.3397521512775e-06,0.00194948960663101,7.85428386069816e-05,2.49651191385407e-05,4.53460905371944e-05,4.53460905371944e-05,1.07779666038946e-06,1.80259732203024e-06,0.0715020795216086,0,0,0,0.00192284797287245,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN16",0.0884189753074781 "HALLMARK_ESTROGEN_RESPONSE_LATE1",0.0676585006223306,0.0496023578657877,0.0774773338523604,7.80793159389701,6.26966856781162,13.137962390685,2.29619863254597e-06,2.951635883009e-06,0.00229081525129264,0.000323799359725374,5.88473054912147e-05,0.00010798426091628,0.00010798426091628,2.35262189301358e-06,4.40166295003361e-06,5.77315972805081e-15,3.61817464877845e-10,0,0,0.00284054754188906,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN16",2.1484923544898e-14 "HALLMARK_ADIPOGENESIS1",0.0439900925189429,0.0366311316354432,0.0494359985133196,4.09415524430765,5.33345340171836,9.75731692540657,1.00514681803277e-06,2.12561079217967e-06,0.00176939470164586,7.58366243250354e-05,2.50928524868758e-05,3.35175443779302e-05,3.35175443779302e-05,9.42613324260935e-07,1.6222227139172e-06,4.2371035458455e-05,9.63623001393188e-08,0,0,0.00170424551150307,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN16",6.74267086591923e-05 "HALLMARK_P53_PATHWAY1",0.0601869212454875,0.0493229325702962,0.0703535585371526,4.26051322063158,7.04677310162538,10.1236016840005,1.89127302894954e-06,4.51084387945722e-06,0.00253024048430317,0.000225882116137406,6.09255404820357e-05,8.33466932852484e-05,8.33466932852484e-05,1.98148882575339e-06,4.21553159117289e-06,2.03958016657957e-05,1.83120185681673e-12,0,0,0.00259331901500309,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN16",3.33594753254183e-05 "HALLMARK_HEME_METABOLISM1",0.0512313830199301,0.0419389300627888,0.0563171794586615,4.32345305826652,4.62905429736576,9.20639318822485,1.85146552307123e-06,2.66807994821904e-06,0.00212592226369881,0.000123289747463427,2.6097908208515e-05,6.97413546989867e-05,6.97413546989867e-05,1.10707261407558e-06,2.3391189869481e-06,1.5360583351498e-05,3.67339449813819e-06,0,0,0.00222506459019823,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN16",2.53076225200785e-05 "HALLMARK_CHOLESTEROL_HOMEOSTASIS1",0.0494624007780606,0.0406353709074141,0.0591087062918049,4.04727319501837,6.26370419267946,11.0598000845391,1.08476188910935e-06,3.57192046936416e-06,0.00215793474379405,0.00012576019509951,8.28527038995788e-05,3.07401368173921e-05,3.07401368173921e-05,2.27169886515229e-06,2.68994779114164e-06,5.18177504136297e-05,3.75938391528052e-10,0,0,0.00208624013177094,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN16",8.14674792599312e-05 "HALLMARK_NOTCH_SIGNALING1",0.0414518615522329,0.03798435775946,0.0554962841565522,1.39038063842193,7.32985014164899,12.0577656959811,3.53267187667541e-06,2.58698557733443e-06,0.00247379414139694,0.000108248888396799,4.29996914659554e-05,4.69079455075938e-05,4.69079455075938e-05,3.57128066513113e-06,2.00927966351737e-06,0.164413322657539,2.30482299912182e-13,0,0,0.00248757691624477,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN16",0.192771752188699 "HALLMARK_ALLOGRAFT_REJECTION1",0.0422240911173675,0.0388726791268356,0.0480622274443094,1.67078297581063,4.92313086026079,7.81603349996802,1.42421552260244e-06,2.49939148057949e-06,0.0019808096837359,4.29963153638926e-05,3.69879578777433e-05,3.31110133440955e-05,3.31110133440955e-05,1.30626026143517e-06,1.28234201083268e-06,0.0947645523557334,8.51704568205491e-07,5.55111512312578e-15,1.66533453693773e-14,0.00183722851789482,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN16",0.115127183440437 "HALLMARK_INTERFERON_GAMMA_RESPONSE1",0.0391233728413272,0.0332405920844584,0.0484024098172802,3.34383255049459,9.40062083200939,10.7826156553919,1.17568157727159e-06,1.81942981706913e-06,0.00173063901329559,7.30519970859565e-05,1.49833223089648e-05,3.61974964463822e-05,3.61974964463822e-05,8.74300080851615e-07,1.87721680360673e-06,0.000826295951183331,0,0,0,0.00167677984059257,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN16",0.00119523251979286 "HALLMARK_ANDROGEN_RESPONSE1",0.0489756766015759,0.0409881511289962,0.0590658293193504,4.37198517371233,8.52886551456942,12.025688651045,1.21150725634067e-06,2.02634532091842e-06,0.00179940339481148,0.000134240744794753,4.20429307112103e-05,5.12013119952056e-05,5.12013119952056e-05,1.29962904440491e-06,2.15977599434359e-06,1.23121888291333e-05,0,0,0,0.00202398616906171,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN16",2.0450754326357e-05 "HALLMARK_TNFA_SIGNALING_VIA_NFKB1",0.0500721696870788,0.0432197203320425,0.0646520378552723,2.97558822375206,10.7521623634533,11.0489897232867,2.02080087060055e-06,3.18249682313687e-06,0.0022810738027818,0.000148557391756129,4.24109386692028e-05,6.79189841231221e-05,6.79189841231221e-05,1.73871985826724e-06,3.66264400452844e-06,0.00292427223538416,0,0,0,0.00232782522023195,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN16",0.00406014657474826 "HALLMARK_PEROXISOME1",0.048178841278776,0.040062802093352,0.0555142582125151,4.16040821938584,5.90224603445275,8.97096310677066,8.93880950684247e-07,2.81165981892086e-06,0.00192497812185103,0.000149368498679824,4.95403290291401e-05,4.24883765606284e-05,4.24883765606284e-05,1.4445962954658e-06,2.86661155833816e-06,3.176792629489e-05,3.58585872106687e-09,0,0,0.00197565979035903,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN16",5.09673687896189e-05 "HALLMARK_INTERFERON_ALPHA_RESPONSE1",0.0531607932596956,0.0422965153078158,0.0616506980570221,4.55339000630379,6.87044653156183,10.7728770031086,2.20933565659613e-06,3.38354443073285e-06,0.00236492707864936,0.000117696701008395,3.97039671191442e-05,7.63787105425751e-05,7.63787105425751e-05,1.42698830993465e-06,3.12764879307344e-06,5.27882778311728e-06,6.4002136923591e-12,0,0,0.00236195645565526,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN16",9.07587934641216e-06 "HALLMARK_TGF_BETA_SIGNALING1",0.0496919984228251,0.0372656624583279,0.053278370432237,5.54513116998585,2.87720996558604,10.0817349424562,2.01612914894066e-06,2.90570695637353e-06,0.00221852115277592,0.00013270222078182,3.60100855519908e-05,7.06119765496536e-05,7.06119765496536e-05,1.45370141379844e-06,2.42266171558577e-06,2.93733886103098e-08,0.00401208539968012,0,0,0.0023497907066629,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN16",6.24649276776208e-08 "HALLMARK_FATTY_ACID_METABOLISM1",0.0428609711256576,0.0348902736746205,0.0483725054511541,4.36669906566321,5.59117436065616,9.66955886976018,1.19709052420127e-06,2.03476470509329e-06,0.00179773614006465,0.000103796012606999,2.69309237617634e-05,5.06129497312843e-05,5.06129497312843e-05,8.71715121591519e-07,1.84406263990119e-06,1.26138327480874e-05,2.25538954179427e-08,0,0,0.0019203089735623,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN16",2.08927708616208e-05 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE1",0.0686224407126257,0.0551920273248241,0.0757139604033467,5.15245121495286,4.30627295074655,8.9770789486652,2.17793934535151e-06,4.51645866706696e-06,0.00258735347651195,0.000306804417479486,7.5448186407469e-05,9.87048456495858e-05,9.87048456495858e-05,2.61191153585521e-06,5.12596437592179e-06,2.57103513590096e-07,1.66028173673727e-05,0,0,0.00284295346006812,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN16",5.04764160236982e-07 "HALLMARK_MTORC1_SIGNALING1",0.0588455096654909,0.0476355014509166,0.0632179332275057,4.8441497732361,2.98932629226576,9.21840094352106,1.18647790972841e-06,4.06873493840804e-06,0.00229242510196875,0.000140718328910826,7.93587548535875e-05,4.44468191507126e-05,4.44468191507126e-05,2.03942865352806e-06,2.75732263517198e-06,1.2715499144722e-06,0.00279593376597842,0,0,0.00224469725839445,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN16",2.32919423585562e-06 "HALLMARK_UV_RESPONSE_UP1",0.0548457837954904,0.0412643940728578,0.0593089369901858,6.7590789442694,3.67839651446133,11.319672662166,1.18522937821449e-06,2.75227852461662e-06,0.00198431547462371,0.000119272928682702,4.60596807417149e-05,4.59797736433796e-05,4.59797736433796e-05,1.37219894819357e-06,2.44111333042279e-06,1.38871136812213e-11,0.000234704883967707,0,0,0.0020448344008111,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN16",3.84264604449794e-11 "HALLMARK_ANGIOGENESIS1",0.0645841693991745,0.0582638689278528,0.0867600044712721,1.95588861074594,9.79937634643001,10.3745537110591,2.87379682223617e-06,7.46828796600882e-06,0.00321591119097605,0.000353921812495918,0.000198301638437107,0.000111079238690926,0.000111079238690926,5.02109805766698e-06,7.44454561776432e-06,0.0504782772880303,0,0,0,0.00346971883309897,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN16",0.0636936202690168 "HALLMARK_MYC_TARGETS_V11",0.0871747345320246,0.0690738818985687,0.0892531142389589,4.66167733331631,0.92605034203328,7.69655140635829,4.4915514651811e-06,1.04854037845168e-05,0.00387000713819728,0.000251418187107933,0.000171251146744074,0.000131679918964706,0.000131679918964706,4.93710024212849e-06,6.77411720463791e-06,3.13642652494117e-06,0.354419818779778,1.3988810110277e-14,4.19664303308309e-14,0.00369291841797713,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN16",5.52161316366889e-06 "HALLMARK_DNA_REPAIR1",0.0702076500637652,0.0546771694659019,0.074780833407594,5.63995955543254,2.67795222788883,10.3876908995106,1.85066640922686e-06,5.63192774094414e-06,0.00273543308274412,0.000191082838583013,9.90917716428017e-05,6.28217366968773e-05,6.28217366968773e-05,2.81629582044145e-06,3.64552237255899e-06,1.70090110884757e-08,0.00740737823955007,0,0,0.00267301282016188,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN16",3.69733771535074e-08 "HALLMARK_KRAS_SIGNALING_UP1",0.0562201964591611,0.0463152704358734,0.0687173316534913,4.08950791216026,7.18071211232006,12.6585209252714,2.61800711560302e-06,3.14824017999967e-06,0.00240130116720138,0.000185147439087975,4.95306032978465e-05,5.98218666129531e-05,5.98218666129531e-05,2.92890676538834e-06,3.03191546760502e-06,4.32289323020196e-05,6.93445301180873e-13,0,0,0.00248009649445887,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN16",6.86989518745609e-05 "HALLMARK_HYPOXIA1",0.0474225779462575,0.0383701202188002,0.0553527774688331,4.66434047541002,6.06041339759863,9.80502649912037,1.44545181290757e-06,2.221174379618e-06,0.0019148436470181,0.000187686304723218,3.87336984632235e-05,6.01781918032145e-05,6.01781918032145e-05,1.61223641533079e-06,2.89994813034374e-06,3.09608400583805e-06,1.35772149079116e-09,0,0,0.00218882152717997,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN16",5.46695914544377e-06 "HALLMARK_SPERMATOGENESIS1",0.0637002379348352,0.0516480519022084,0.0697445610092544,5.44374838913989,5.54111086108892,10.5702806928364,1.96492996342039e-06,2.83664405871693e-06,0.0021912494203393,0.00017269357700017,3.05678017525953e-05,8.88689218329847e-05,8.88689218329847e-05,1.08987588010124e-06,2.83100508030038e-06,5.21708989342784e-08,3.00558855581556e-08,0,0,0.00243688650171244,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN16",1.08975092622933e-07 "HALLMARK_OXIDATIVE_PHOSPHORYLATION1",0.0742550278774566,0.062625568139051,0.0800800922483278,3.69960549313205,3.31052829035256,8.27790484804545,3.3168923042095e-06,6.46427488811382e-06,0.00312748576212959,0.00021696464501123,9.47660958066443e-05,0.000112186601104414,0.000112186601104414,2.99604205220487e-06,4.34605841948625e-06,0.000215934869143952,0.000931200386796949,2.22044604925031e-16,6.66133814775094e-16,0.00311297928728314,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN16",0.000325146486700753 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION1",0.0487361008537033,0.0474499459065953,0.063828341910761,0.526036018987028,10.2884789875088,9.64170447551121,1.64744956827069e-06,4.23054643479154e-06,0.00242445787817859,0.000105368235469028,8.35656087090882e-05,5.33835506516629e-05,5.33835506516629e-05,2.05181592164102e-06,2.78559318120581e-06,0.598863181171446,0,0,0,0.00241060053472642,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN16",0.637342172902824 "HALLMARK_MYC_TARGETS_V21",0.0699540341799674,0.0555108022606297,0.0719031673404005,4.81608820010817,1.23082979891997,7.83203253127112,2.7904261257897e-06,6.10330512960847e-06,0.0029822359489816,0.000181304013208602,9.51797846859212e-05,0.000105638718654013,0.000105638718654013,2.40776603485408e-06,4.28060677246306e-06,1.4639983310083e-06,0.218386527914031,4.88498130835069e-15,1.46549439250521e-14,0.00299325571998136,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN16",2.64871082656271e-06 "HALLMARK_E2F_TARGETS1",0.0818839205213523,0.0606869887923041,0.0804255792099943,6.75991857238279,-0.884819598789983,9.5380292637345,2.70900305564458e-06,7.02347697069406e-06,0.00311969229673996,0.000178180147934983,0.000103441425907068,9.87750756079892e-05,9.87750756079892e-05,2.61649487231503e-06,4.18267353421735e-06,1.38069555788434e-11,0.376253937228339,0,0,0.00312321902407779,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN16",3.82947635866033e-11 "HALLMARK_IL6_JAK_STAT3_SIGNALING1",0.0391278087622696,0.0303832080964805,0.0435044240314918,5.22487606784692,4.5005362898793,11.5340857533612,1.35454998570499e-06,1.3465459025822e-06,0.0016435011068713,6.15138859069726e-05,1.22808134852121e-05,3.92425381015693e-05,3.92425381015693e-05,8.45688714727033e-07,1.19414164681121e-06,1.7427179299645e-07,6.7782230830371e-06,0,0,0.00171804564146525,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN16",3.4677432921121e-07 "HALLMARK_PROTEIN_SECRETION1",0.0615663822325598,0.0515964206290374,0.0675595569028204,3.48152995140646,4.03806309137334,7.98060808932099,2.75297586250454e-06,5.34764436382762e-06,0.00284615885472546,0.000142307202247317,7.20740740908664e-05,9.38637421101724e-05,9.38637421101724e-05,2.10276247950574e-06,3.9009624382558e-06,0.000498558020934681,5.38943596741781e-05,1.55431223447522e-15,4.66293670342566e-15,0.00275243177579501,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN16",0.000730142257309072 "HALLMARK_UV_RESPONSE_DN1",0.047570105753559,0.0406298318270149,0.0592264054411942,3.32121465576739,9.35437028481641,10.4449247273489,1.74473847242352e-06,2.52202161977081e-06,0.00206561373257304,0.000186126559340489,5.01072166116411e-05,8.14531335254247e-05,8.14531335254247e-05,1.45271695507783e-06,3.06997062757321e-06,0.000896265765903292,0,0,0,0.00241576706836518,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN16",0.00129326201313162 "HALLMARK_APOPTOSIS1",0.0519763665553804,0.0417382243773198,0.0614915970981166,4.98012871205477,7.64380102224688,11.696931756552,1.51862488827442e-06,2.60768344461307e-06,0.00203133166491528,0.00016853035080144,4.1008351928701e-05,6.47638090668541e-05,6.47638090668541e-05,1.44960098504845e-06,2.75192831178814e-06,6.35419984185148e-07,2.1094237467878e-14,0,0,0.002230761967618,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN16",1.20137283183559e-06 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY1",0.0421074373486542,0.0357281524484558,0.0481392052593079,3.40261931073816,5.18354055329245,8.90541206618204,1.50901581340529e-06,1.90591897197266e-06,0.0018479542162559,0.000100531078460872,3.60058888598477e-05,5.1805786617452e-05,5.1805786617452e-05,1.25405480855059e-06,1.84226823638913e-06,0.00066743206733344,2.17712863070929e-07,0,0,0.00201327412960085,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN16",0.000971411028693224 "HALLMARK_COMPLEMENT1",0.0416732509125227,0.0341583323623498,0.0500776595760203,4.40554712077004,7.52465929588377,11.5410859276519,1.16051034459902e-06,1.64919394511451e-06,0.00167621725611972,9.71909186060823e-05,2.64781845238479e-05,3.78057090293766e-05,3.78057090293766e-05,1.1475002530525e-06,1.80263757803228e-06,1.05517210717831e-05,5.28466159721575e-14,0,0,0.00177797716826547,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN16",1.77016033957446e-05 "HALLMARK_APICAL_JUNCTION1",0.0467409813713996,0.038766205271832,0.0566401373062496,4.30533634468227,8.35940449942406,11.0339784281227,1.37636455929085e-06,1.95465209739998e-06,0.00182510730004864,0.000152712880515196,2.5918520659609e-05,5.35466823124811e-05,5.35466823124811e-05,1.30231522651213e-06,2.52407318499227e-06,1.6673221397534e-05,0,0,0,0.00202371992192172,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN16",2.73468735892608e-05 "HALLMARK_GLYCOLYSIS1",0.0650122308992198,0.0481756791191288,0.0698857170228109,7.27150378073203,3.25599822926476,11.251500235016,1.65978394950701e-06,3.60136449004008e-06,0.00229371934629045,0.000253287631886331,5.21009381948996e-05,7.21865101969742e-05,7.21865101969742e-05,2.14032563112419e-06,3.62306223693646e-06,3.55493412484975e-13,0.00112994456203097,0,0,0.00254711413623855,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN16",1.13295461539927e-12 "HALLMARK_PI3K_AKT_MTOR_SIGNALING1",0.0461640483531542,0.0361791997405679,0.0475256115447262,5.43814420332908,1.51632575151255,8.6427802276898,1.21044204211821e-06,2.06073476183068e-06,0.00180863948976817,9.3301536849747e-05,2.14084356792823e-05,5.15242047477971e-05,5.15242047477971e-05,7.06288718482109e-07,1.62349546095477e-06,5.38383932990882e-08,0.129437003219689,0,0,0.00193522936143502,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN16",1.12060089415447e-07 "HALLMARK_G2M_CHECKPOINT1",0.0959076730001498,0.0699030363083021,0.093237682375661,7.21133133623113,-1.32262153959119,9.50736286102968,3.41952979974642e-06,9.48428215342853e-06,0.00359218762777989,0.000281209123883727,0.000139209532830226,0.000119478450813327,0.000119478450813327,3.97519402117412e-06,5.92396301464297e-06,5.54001289287953e-13,0.185961267509361,0,0,0.00362125373787674,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN16",1.71448820053324e-12 "HALLMARK_APICAL_SURFACE1",0.0565427754443983,0.0390069805726537,0.0649748916330967,8.66265361033678,5.03275130213097,12.0568621456388,1.34281053446699e-06,2.65497302377326e-06,0.00199944581277919,0.000343782887218521,5.26721779750602e-05,6.41597667502885e-05,6.41597667502885e-05,2.70712805478303e-06,4.5387977662594e-06,0,4.8349018455518e-07,0,0,0.00248238784674607,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN16",0 "HALLMARK_XENOBIOTIC_METABOLISM1",0.0537185284077117,0.044946988463444,0.0626999914057208,4.447592548814,6.79676027824831,10.790965468186,1.42008825369807e-06,2.3694827411833e-06,0.00194668204771128,0.00017591640331551,3.51768322759431e-05,5.34064050502054e-05,5.34064050502054e-05,1.64618504643197e-06,2.60659356267894e-06,8.68380485830045e-06,1.06998854221274e-11,0,0,0.00213112505808481,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN16",1.46726357950594e-05 "HALLMARK_WNT_BETA_CATENIN_SIGNALING1",0.055543579074023,0.0368445282613217,0.0644188008422194,6.75593538076791,5.0349111470487,13.4134420369328,3.97286748019251e-06,3.58782712692719e-06,0.00274967172715575,0.000319687980496702,5.28674244086157e-05,0.000139780361615169,0.000139780361615169,3.00724004898164e-06,4.1259821181403e-06,1.41917588791785e-11,4.78070530718355e-07,0,0,0.00324393181046245,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN16",3.90854998639669e-11 "HALLMARK_KRAS_SIGNALING_DN1",0.0656416687845207,0.058651630074657,0.0749957035281199,2.65317203773955,5.7116936654848,7.99788897603202,2.55639387131979e-06,4.28470672392996e-06,0.00261554976921674,0.000209839043738514,8.14171053309474e-05,9.16967139204805e-05,9.16967139204805e-05,2.58205786511764e-06,4.07609018226946e-06,0.00797392177683309,1.11857305640228e-08,1.33226762955019e-15,3.99680288865056e-15,0.00277258328749936,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN16",0.0106318957024441 "HALLMARK_COAGULATION1",0.0531330741087067,0.0471657337757762,0.0615596379911068,2.53985004076489,6.95648910658918,7.98715466758517,1.92995744677694e-06,3.49012372434456e-06,0.00232810677829036,0.000113449705521458,4.17746445095348e-05,6.86483471025825e-05,6.86483471025825e-05,1.36730641521003e-06,3.14767848186955e-06,0.0110900007731172,3.48854278797717e-12,1.33226762955019e-15,3.99680288865056e-15,0.00227617092848154,"HALLMARK_COAGULATION","kendall_tau","HN18","HN16",0.0146151719539119 "HALLMARK_HEDGEHOG_SIGNALING1",0.0580313852159569,0.0491392049777658,0.0704759650339009,3.57985208367498,6.87995624827136,8.66179746215021,1.45941790108715e-06,4.6105989367447e-06,0.00246374041608118,0.000230516372107946,0.000101553843507397,4.77568473907742e-05,4.77568473907742e-05,3.17181788616962e-06,5.96793469051411e-06,0.000343788754816332,5.98698868259362e-12,0,0,0.00240542730873848,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN16",0.000509830486335443 "CELL_CYCLE1",0.0578870825417588,0.047158913074406,0.0611998150519277,4.67504129506807,3.31770177553802,8.95364569641719,1.31341517074861e-06,3.85257868045622e-06,0.00227288227834281,8.86760715646862e-05,5.28598483200758e-05,6.28009883007112e-05,6.28009883007112e-05,8.97006636392607e-07,2.35917935912721e-06,2.93894475933421e-06,0.000907613339422575,0,0,0.0022005373700709,"CELL_CYCLE","kendall_tau","HN18","HN16",5.20511903159191e-06 "PEMT1",0.0815780726068496,0.0705500071133874,0.0994488039347194,2.99370513070482,7.93495230520612,10.2030820705759,3.93465860359663e-06,9.53536583995352e-06,0.00367015319074697,0.000427169181074416,0.000206946062806268,0.000172494158261425,0.000172494158261425,4.97219579704898e-06,7.92226055346537e-06,0.00275612167563066,1.99840144432528e-15,0,0,0.00390282158831739,"PEMT","kendall_tau","HN18","HN16",0.00383573856868835 "EPI_DIFF11",0.0801683328661746,0.0541046684145276,0.0980110460744264,7.36667088005629,8.5489863438405,13.4126311822548,8.02719809314447e-06,4.39061368013162e-06,0.00352389156661724,0.00103438072094425,8.08405697999195e-05,0.000430436458413104,0.000430436458413104,4.2560468627329e-06,1.06158654544633e-05,1.74971148680925e-13,0,0,0,0.00510804556891438,"EPI_DIFF1","kendall_tau","HN18","HN16",5.77994581035864e-13 "EPI_DIFF21",0.0857198812378668,0.0618331402556755,0.0914443326626425,7.30996832902645,3.193036975812,10.3914025577119,3.54320841508303e-06,7.03461685452143e-06,0.00325235687918845,0.000566389976355103,9.62357265732721e-05,0.000204056314125721,0.000204056314125721,3.11410346837936e-06,8.02013881277987e-06,2.67119659724813e-13,0.0014078491794316,0,0,0.00386380882733616,"EPI_DIFF2","kendall_tau","HN18","HN16",8.60637588592821e-13 "STRESS1",0.0672910861296235,0.0540392788034752,0.0832582915968354,4.03909203518587,8.5733103516445,10.9714588084888,4.14499835610827e-06,6.51922566062622e-06,0.00326561234942767,0.000370384147657604,7.25696868190146e-05,0.000155541946836736,0.000155541946836736,3.36865205195524e-06,6.99254864789199e-06,5.36585091186481e-05,0,0,0,0.00342542625275711,"STRESS","kendall_tau","HN18","HN16",8.41365422980402e-05 "HYPOXIA1",0.0665299936038447,0.0543127658965543,0.0811355247543808,4.37162249698503,8.10162138360785,12.0945025793316,2.8492370719842e-06,4.8609247514585e-06,0.00277671781487473,0.000273516929503565,7.21840702872928e-05,9.34342717589971e-05,9.34342717589971e-05,3.15005585019536e-06,4.81847952130505e-06,1.23326625367515e-05,4.44089209850063e-16,0,0,0.002881287007076,"HYPOXIA","kendall_tau","HN18","HN16",2.04558690313395e-05 "HALLMARK_PANCREAS_BETA_CELLS2",0.0711541191757019,0.0582487986743306,0.119482046982047,5.63593888279486,27.9875797424277,23.9125928541127,2.7798445003134e-06,2.36345951447541e-06,0.00226788536191511,0.000214378300724384,0.00028130403750498,7.98644973762398e-05,7.98644973762398e-05,2.88171177202569e-06,6.457242699032e-06,1.74107124273348e-08,0,0,0,0.00323090858246453,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN17",3.77767487353243e-08 "HALLMARK_MYOGENESIS2",0.0517935644305804,0.0433837044668863,0.0944115327720855,4.48722777910627,34.4072079765792,23.6155278333707,1.85540433717388e-06,1.55713581383564e-06,0.00184730618767153,0.000190257410762049,0.000154873495024004,7.87319073741318e-05,7.87319073741318e-05,1.43421639606961e-06,4.56894606632079e-06,7.21559186089848e-06,0,0,0,0.00267208339805095,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN17",1.22623353011801e-05 "HALLMARK_IL2_STAT5_SIGNALING2",0.047849951194823,0.0359501037470673,0.0714374437120668,7.91259124680519,27.6130964687197,26.0413766369473,1.323341741666e-06,8.38412040759536e-07,0.00147029037350638,6.06109597022474e-05,4.13415119725133e-05,4.38155544926402e-05,4.38155544926402e-05,6.29681491614239e-07,1.75703041346097e-06,2.44249065417534e-15,0,0,0,0.00201248648239062,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN17",9.47976570729441e-15 "HALLMARK_ESTROGEN_RESPONSE_EARLY2",0.0549660610348763,0.0416806622224135,0.110354494333138,6.91838138330068,38.7455376873889,28.6614030581491,1.99671460451586e-06,1.59085471790633e-06,0.00189408799225965,0.000230783554709684,0.000229681999975539,8.39152958080772e-05,8.39152958080772e-05,1.94359474702905e-06,5.64100165037635e-06,4.56834570172759e-12,0,0,0,0.00333285178946109,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN17",1.33309542065302e-11 "HALLMARK_BILE_ACID_METABOLISM2",0.054052772674304,0.0500296841862191,0.0849604114782686,2.24019488032174,26.5437215246467,22.9817036806476,1.8903230215468e-06,1.23480953462695e-06,0.00176780444511653,7.54978698043838e-05,8.6405016452921e-05,5.02455864802602e-05,5.02455864802602e-05,1.25583871818992e-06,2.21020657192683e-06,0.0250782738989899,0,0,0,0.00205347620553273,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN17",0.0323023549892794 "HALLMARK_MITOTIC_SPINDLE2",0.0989643076637039,0.0844883216857984,0.125844162370293,5.81654662645117,23.1948824969784,21.7601064573029,3.55807105951202e-06,2.53585304958983e-06,0.00246858747244287,0.00019982105670148,0.000190478007069419,0.000151185671145422,0.000151185671145422,1.24297979953907e-06,3.51203272002636e-06,6.00757910085292e-09,0,0,0,0.00319375049730415,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN17",1.33300245709491e-08 "HALLMARK_INFLAMMATORY_RESPONSE2",0.0412617631535964,0.032999325922355,0.0739242442919921,5.26412712484306,32.2203016340604,25.9415794818294,1.46075757508481e-06,9.02805063827062e-07,0.00153738825249573,7.72240168292011e-05,7.9867945091544e-05,4.64361160520789e-05,4.64361160520789e-05,9.27635598411835e-07,2.38875882797634e-06,1.40856963204428e-07,0,0,0,0.00208787167723204,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN17",2.82193847918921e-07 "HALLMARK_ESTROGEN_RESPONSE_LATE2",0.0676585006223306,0.0483822696424001,0.109551884965955,9.89932455065417,35.1233478313893,28.6604843486322,2.29619863254597e-06,1.39549393727145e-06,0.00192137777904748,0.000207235990089901,0.000171924744383529,0.000104117525894282,0.000104117525894282,1.32265332438383e-06,4.45516851227475e-06,0,0,0,0,0.00327004454583683,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN17",0 "HALLMARK_ADIPOGENESIS2",0.0439900925189429,0.0399082285013679,0.0713180549609121,2.86352536387512,31.6984786034182,22.1246697726838,1.00514681803277e-06,9.26812444100388e-07,0.0013899493739461,3.89940961176821e-05,8.44783240218161e-05,3.13745702030842e-05,3.13745702030842e-05,6.43254705777752e-07,1.91547529611553e-06,0.00418955270253307,0,0,0,0.00169989754950923,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN17",0.00572896974206848 "HALLMARK_P53_PATHWAY2",0.0601869212454875,0.0504327851840949,0.106702546281189,4.99157422578523,35.8301049938379,25.4245479613022,1.89127302894954e-06,1.82731275605754e-06,0.00192836349918968,0.000113485002984876,0.000236441307439477,6.41541092449485e-05,6.41541092449485e-05,1.58539445369421e-06,4.79828062465862e-06,5.98891591874207e-07,0,0,0,0.00281072493904425,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN17",1.13413286963618e-06 "HALLMARK_HEME_METABOLISM2",0.0512313830199301,0.0374555938021136,0.0796429137027127,7.83931401331676,26.0258371214646,26.7226108905011,1.85146552307123e-06,1.13653138011851e-06,0.00172858233914088,7.75755660941957e-05,5.96624989865312e-05,5.23122857465225e-05,5.23122857465225e-05,1.09173542531775e-06,2.39233316417002e-06,4.44089209850063e-15,0,0,0,0.00235051679453238,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN17",1.66852687151333e-14 "HALLMARK_CHOLESTEROL_HOMEOSTASIS2",0.0494624007780606,0.0432496542085583,0.103037635571882,3.54234814419683,42.947420394459,26.8912821181393,1.08476188910935e-06,1.89122721726703e-06,0.00172510553485182,6.02668811220865e-05,0.000269040775514201,3.06024452818065e-05,3.06024452818065e-05,1.45615910924554e-06,4.84316108308233e-06,0.000396581688750564,0,0,0,0.00272746978809108,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN17",0.000584436172895567 "HALLMARK_NOTCH_SIGNALING2",0.0414518615522329,0.0318445510106457,0.0835492162407485,4.36513137643167,18.5903496939448,30.4782392116723,3.53267187667541e-06,1.21138260932817e-06,0.00217808505022269,0.000104169242824526,7.09457576557743e-05,-1.8764035527094e-05,-1.8764035527094e-05,5.02784034203615e-06,2.77792660771044e-06,1.27046378892715e-05,0,0,0,0.00253035366388765,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN17",2.10135782809891e-05 "HALLMARK_ALLOGRAFT_REJECTION2",0.0422240911173675,0.035556316312462,0.0659656259455758,4.44030332316173,24.0228441524844,22.358762053597,1.42421552260244e-06,7.30732681513445e-07,0.00146797418373617,6.07456354021563e-05,5.9117133191719e-05,4.06188570120291e-05,4.06188570120291e-05,8.7671697441356e-07,1.74976949508257e-06,8.98321711328975e-06,0,0,0,0.00171221822106435,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN17",1.51567623030542e-05 "HALLMARK_INTERFERON_GAMMA_RESPONSE2",0.0391233728413272,0.0324665004454995,0.0667390573948216,4.58659146203472,30.2639370668417,24.7104470352737,1.17568157727159e-06,8.30813010936255e-07,0.00141650788497906,4.85760721177274e-05,6.27713668074452e-05,3.43078072065003e-05,3.43078072065003e-05,7.32646720979643e-07,1.82367547843428e-06,4.505410769573e-06,0,0,0,0.00181369558679561,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN17",7.76886079914641e-06 "HALLMARK_ANDROGEN_RESPONSE2",0.0489756766015759,0.0410608749370838,0.0954632296995933,4.9051256463021,40.0440966727428,28.0059323709496,1.21150725634067e-06,1.29212593886654e-06,0.00158228733016706,7.62099047604773e-05,0.000198243948392586,3.88112619834043e-05,3.88112619834043e-05,1.24770975694296e-06,3.67342154600975e-06,9.33675525338629e-07,0,0,0,0.00254332763703634,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN17",1.73186501230004e-06 "HALLMARK_TNFA_SIGNALING_VIA_NFKB2",0.0500721696870788,0.0389103836396684,0.102242623289608,5.43338511061665,40.1988367736953,28.1859420982297,2.02080087060055e-06,2.09933477549648e-06,0.00202981172676114,9.54914737353527e-05,0.00017220437515234,5.74141186130582e-05,5.74141186130582e-05,1.58431087676413e-06,4.9487583225408e-06,5.52948906662465e-08,0,0,0,0.00303839103694517,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN17",1.14685699159622e-07 "HALLMARK_PEROXISOME2",0.048178841278776,0.0490163780672548,0.0833383685925091,-0.575410409969696,35.9630871895345,22.1532837982232,8.93880950684247e-07,1.12473557455698e-06,0.00142078025227029,3.68369908319557e-05,0.000167200989852031,2.82751266454636e-05,2.82751266454636e-05,8.55811218688962e-07,2.30031761303497e-06,0.565013765418171,0,0,0,0.00180759013676483,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN17",0.60405108011979 "HALLMARK_INTERFERON_ALPHA_RESPONSE2",0.0531607932596956,0.0408069614541672,0.0897777757969934,6.37021238375047,28.371375527321,25.3887526702962,2.20933565659613e-06,1.45159689110995e-06,0.00191335635669524,0.000112305511489221,0.000143013217891792,6.57706828110383e-05,6.57706828110383e-05,1.56572890304035e-06,3.62041958874325e-06,1.88766557940312e-10,0,0,0,0.00261784374458825,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN17",4.73325100507051e-10 "HALLMARK_TGF_BETA_SIGNALING2",0.0496919984228251,0.0400391803308972,0.0873133249233878,4.95673322552893,30.1158128001128,23.5714479042632,2.01612914894066e-06,1.67629717856474e-06,0.00192156871527026,6.68822431177914e-05,0.000173795833164,5.45985534897717e-05,5.45985534897717e-05,1.46055482567946e-06,3.92230350667104e-06,7.16883012730207e-07,0,0,0,0.00244421137233627,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN17",1.34458440665187e-06 "HALLMARK_FATTY_ACID_METABOLISM2",0.0428609711256576,0.0367795138446028,0.0764387334023712,3.93483619214414,36.0355819402056,24.3923847891562,1.19709052420127e-06,1.09161165722507e-06,0.0015128457229428,4.7395591130356e-05,0.000104652083225919,3.79580853946838e-05,3.79580853946838e-05,7.68241260211304e-07,2.543502968381e-06,8.32534581844957e-05,0,0,0,0.00198499028766155,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN17",0.000128993500428151 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE2",0.0686224407126257,0.0588164433529175,0.102221860079003,4.94528140945286,28.5074125685449,22.8476166651167,2.17793934535151e-06,1.65395214475087e-06,0.00195752177257429,0.000139873892302819,0.000107643406343684,7.74929594814762e-05,7.74929594814762e-05,1.28914615990773e-06,3.50915931517427e-06,7.60339462280157e-07,0,0,0,0.00254706988348456,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN17",1.42382039433354e-06 "HALLMARK_MTORC1_SIGNALING2",0.0588455096654909,0.0507147656862187,0.0949180284539581,4.91443861772624,39.0224610398301,23.7284291320409,1.18647790972841e-06,1.45076123677155e-06,0.0016239578647551,7.99879985864654e-05,0.000172847488174291,5.34477398816116e-05,5.34477398816116e-05,7.54522741637649e-07,3.37032922806474e-06,8.90372148676377e-07,0,0,0,0.00235631997512727,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN17",1.65939405204979e-06 "HALLMARK_UV_RESPONSE_UP2",0.0548457837954904,0.0404658449935616,0.0848521355756379,9.55216508260509,32.3721001258948,27.6349690372187,1.18522937821449e-06,9.81034291598975e-07,0.00147182324679747,8.39629080253528e-05,0.000102133683073409,4.67347820624145e-05,4.67347820624145e-05,7.59180957354239e-07,2.47976258256722e-06,0,0,0,0,0.00240018791220427,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN17",0 "HALLMARK_ANGIOGENESIS2",0.0645841693991745,0.0451974221883036,0.113886930529788,8.52808412710897,35.5746242131485,27.8505318167906,2.87379682223617e-06,2.19401799862818e-06,0.00225118076148148,0.000195618016937406,0.000189917756570278,0.000105905328543445,0.000105905328543445,1.82071019521963e-06,5.98294416976629e-06,0,0,0,0,0.00354077168900134,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN17",0 "HALLMARK_MYC_TARGETS_V12",0.0871747345320246,0.0651825751978353,0.106740234031235,7.80040658325666,13.4639259362043,19.7215945577223,4.4915514651811e-06,3.35724298020572e-06,0.00280156999651746,0.000175590470438984,0.000133680420378418,0.000144869584769816,0.000144869584769816,2.01173030071543e-06,4.3403591073608e-06,6.21724893790088e-15,0,0,0,0.00337892108646643,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN17",2.3064620665525e-14 "HALLMARK_DNA_REPAIR2",0.0702076500637652,0.0613165445128695,0.101882912962458,4.57746033924748,26.8227395788635,21.9704580379023,1.85066640922686e-06,1.82212115411833e-06,0.00191645181607709,0.000100286319543036,0.000170043381192336,6.25705470231564e-05,6.25705470231564e-05,1.29455032146848e-06,3.30921224360605e-06,4.70654985895713e-06,0,0,0,0.00251154265759588,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN17",8.10381059170364e-06 "HALLMARK_KRAS_SIGNALING_UP2",0.0562201964591611,0.0396944937481275,0.0926668455311671,8.59714895968185,24.0922832512036,30.2902447318686,2.61800711560302e-06,9.76963322821711e-07,0.00189604072699526,0.000143681931846119,9.03656866805824e-05,6.05359273191308e-05,6.05359273191308e-05,2.18854411956943e-06,2.95839055955636e-06,0,0,0,0,0.00279425383735796,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN17",0 "HALLMARK_HYPOXIA2",0.0474225779462575,0.0358540464133322,0.0796122495594857,7.2183693408114,32.5824299228679,27.1264641301526,1.44545181290757e-06,1.02304049770272e-06,0.00157114363143867,7.33660383076574e-05,8.42959786283414e-05,4.72115207352827e-05,4.72115207352827e-05,8.76036710719724e-07,2.50215153507536e-06,5.26245713672324e-13,0,0,0,0.00228137876402677,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN17",1.6392813032932e-12 "HALLMARK_SPERMATOGENESIS2",0.0637002379348352,0.0565625181461193,0.0962681916321698,4.04872983278933,29.3228645647586,23.799206471764,1.96492996342039e-06,1.04307278016937e-06,0.00173435946204637,0.000130947498447883,0.000118091385293723,7.43588841819335e-05,7.43588841819335e-05,1.13358237270113e-06,2.6834292083194e-06,5.14963482063369e-05,0,0,0,0.00227344043106949,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN17",8.10705562123857e-05 "HALLMARK_OXIDATIVE_PHOSPHORYLATION2",0.0742550278774566,0.0616551594818169,0.110118986642513,4.83005842479534,24.74480361675,19.5942527081276,3.3168923042095e-06,3.38809391211939e-06,0.00258939881368801,0.000145875736586774,0.00016936159291739,0.000100500899855071,0.000100500899855071,2.00062451791896e-06,6.01755671814769e-06,1.36492994307069e-06,0,0,0,0.00306031990809379,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN17",2.48861645434284e-06 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION2",0.0487361008537033,0.0395303444550745,0.101163775587896,4.92571353778587,36.2314116193599,27.376605305896,1.64744956827069e-06,1.74540621629119e-06,0.00184197062532546,0.000125703875885197,0.000213125951731704,4.19053580959939e-05,4.19053580959939e-05,1.99387466779107e-06,4.96843057084804e-06,8.40530616441626e-07,0,0,0,0.00289385167702343,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN17",1.57148490450771e-06 "HALLMARK_MYC_TARGETS_V22",0.0699540341799674,0.0560690394030163,0.0896275301629204,6.41089989110409,18.0091089913216,19.7047090968471,2.7904261257897e-06,1.8004444533123e-06,0.00214263169469277,0.000162336312289213,7.37705125554329e-05,0.000107804849875474,0.000107804849875474,1.09337965344283e-06,2.80044601408168e-06,1.44663170331683e-10,0,0,0,0.00262568845997413,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN17",3.65857824322707e-10 "HALLMARK_E2F_TARGETS2",0.0818839205213523,0.0731041149555384,0.103422983121476,4.00956046992494,21.674409298909,19.0556608311013,2.70900305564458e-06,1.98586058893158e-06,0.00216676340299908,0.000145604501715042,0.000159900765241406,0.00011711115739284,0.00011711115739284,8.87549915843976e-07,2.4315000522769e-06,6.08318737609359e-05,0,0,0,0.00267497199718971,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN17",9.50043606146887e-05 "HALLMARK_IL6_JAK_STAT3_SIGNALING2",0.0391278087622696,0.0267726981832324,0.0544872137574624,8.67329985952737,17.4112708838124,24.1850077833332,1.35454998570499e-06,5.74648598622642e-07,0.00138895593318422,6.00654638391548e-05,2.72560139664086e-05,4.15796172438883e-05,4.15796172438883e-05,6.78193930732823e-07,1.21317353263345e-06,0,0,0,0,0.00176020446932994,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN17",0 "HALLMARK_PROTEIN_SECRETION2",0.0615663822325598,0.051950392987627,0.101564569567859,4.22528852076085,28.2990023282938,22.1759729642757,2.75297586250454e-06,2.3263734023969e-06,0.00225374117078724,8.61804658260149e-05,0.000207342731501721,7.34693631948124e-05,7.34693631948124e-05,1.8977372632767e-06,4.90548551651117e-06,2.38634836458029e-05,0,0,0,0.00270241349188633,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN17",3.87616806180445e-05 "HALLMARK_UV_RESPONSE_DN2",0.047570105753559,0.0352653140612522,0.0876166783553147,6.9936134303166,36.2176124604376,27.1980636647741,1.74473847242352e-06,1.25086471785348e-06,0.0017307810925351,0.000118420083172833,0.000129894986527763,6.51559501933735e-05,6.51559501933735e-05,1.12261880371505e-06,3.6049302476865e-06,2.6789681584205e-12,0,0,0,0.0026419196768282,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN17",7.91574511131284e-12 "HALLMARK_APOPTOSIS2",0.0519763665553804,0.0428782436782635,0.0957781990266462,5.26793230427642,40.3541514066711,27.6061803855877,1.51862488827442e-06,1.36416886710757e-06,0.0016978791934004,0.000100615197040441,0.000146930190015009,5.6153210028209e-05,5.6153210028209e-05,1.0781704378028e-06,3.57196022319903e-06,1.37968963809243e-07,0,0,0,0.00259874152412208,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN17",2.77023632347488e-07 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY2",0.0421074373486542,0.0305115351644373,0.0685552698919951,7.53184984394404,22.4968999665708,27.5715084334441,1.50901581340529e-06,7.612976317555e-07,0.00150675593417142,6.22653805596451e-05,6.38855637502675e-05,3.02846579822583e-05,3.02846579822583e-05,1.28208520676329e-06,1.80390482993359e-06,4.9960036108132e-14,0,0,0,0.0020536976540672,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN17",1.70793611811521e-13 "HALLMARK_COMPLEMENT2",0.0416732509125227,0.0320263006590265,0.0722999343451534,6.65122087909244,32.7872741723972,27.5231183092544,1.16051034459902e-06,8.43158315793043e-07,0.00141551003542612,4.8055894652693e-05,7.91851432924151e-05,3.39910809244795e-05,3.39910809244795e-05,7.7254797394997e-07,2.04114637132815e-06,2.90671930969211e-11,0,0,0,0.00204096911816761,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN17",7.8222011629243e-11 "HALLMARK_APICAL_JUNCTION2",0.0467409813713996,0.0342925301648706,0.0791544073179752,7.83573022700986,31.4880037342898,27.9448985366156,1.37636455929085e-06,1.04753281516999e-06,0.00155688707826253,8.13842087718265e-05,6.87817634916783e-05,4.2226338648174e-05,4.2226338648174e-05,9.59643104051634e-07,2.47721000925377e-06,4.66293670342566e-15,0,0,0,0.00235201584927056,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN17",1.74637374625114e-14 "HALLMARK_GLYCOLYSIS2",0.0650122308992198,0.0496185977975972,0.0949090713526529,9.10301046304782,24.5947851873531,28.0832981994599,1.65978394950701e-06,1.09986141890955e-06,0.00166121803759066,9.93222608319348e-05,9.77856746091198e-05,4.50773018480337e-05,4.50773018480337e-05,1.37762598587954e-06,2.50086314333261e-06,0,0,0,0,0.00253556004105355,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN17",0 "HALLMARK_PI3K_AKT_MTOR_SIGNALING2",0.0461640483531542,0.0374506024202073,0.0661934058005487,5.85859397191389,23.5097766203009,20.2623299855488,1.21044204211821e-06,9.01598491064113e-07,0.00145328611538896,5.92794741444492e-05,6.43804212366985e-05,4.21093928226141e-05,4.21093928226141e-05,6.2583353378391e-07,1.91223862187241e-06,4.6680244114583e-09,0,0,0,0.00176899861246554,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN17",1.04166920453035e-08 "HALLMARK_G2M_CHECKPOINT2",0.0959076730001498,0.0842458798552031,0.116307298396746,4.66239092885287,19.2549818395251,18.4910238618116,3.41952979974642e-06,2.73670870944759e-06,0.00248117683956505,0.000182233848724072,0.000206640886527859,0.000151373513033291,0.000151373513033291,1.0224271371685e-06,2.90637775359814e-06,3.125567466844e-06,0,0,0,0.00310264641940596,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN17",5.51074563869348e-06 "HALLMARK_APICAL_SURFACE2",0.0565427754443983,0.0395299181498633,0.0893535551833649,11.3727287278163,26.4210916548706,30.2785993321319,1.34281053446699e-06,7.95009502097892e-07,0.00146212859782062,0.000160838895095806,9.2810377251392e-05,4.65757497372828e-05,4.65757497372828e-05,1.44216764580027e-06,2.60769218734344e-06,0,0,0,0,0.00271871637909705,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN17",0 "HALLMARK_XENOBIOTIC_METABOLISM2",0.0537185284077117,0.0394854349115014,0.0877092714655529,8.91883389015511,30.5383933300211,28.9420639485003,1.42008825369807e-06,1.0266391035251e-06,0.001564201827522,0.000113027138358446,8.29743763465854e-05,4.68994154223974e-05,4.68994154223974e-05,1.13887916255618e-06,2.6762880246954e-06,0,0,0,0,0.00255632022474387,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN17",0 "HALLMARK_WNT_BETA_CATENIN_SIGNALING2",0.055543579074023,0.0330011081660574,0.0994419305046483,9.47030374581686,22.5847428301212,30.570981490823,3.97286748019251e-06,1.59311488644775e-06,0.00235923342775577,0.000271487928140702,7.72226826772932e-05,8.63813590289836e-05,8.63813590289836e-05,3.67803626683741e-06,4.62336202847179e-06,0,0,0,0,0.00359550553556363,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN17",0 "HALLMARK_KRAS_SIGNALING_DN2",0.0656416687845207,0.056252546393854,0.105262277433882,4.50452526677124,31.4199703631966,23.2035076701638,2.55639387131979e-06,1.68822761787827e-06,0.00206024791935293,0.000163173649039026,0.000175241618849247,9.66991219547271e-05,9.66991219547271e-05,1.490123088669e-06,4.36125814815005e-06,6.65214832396011e-06,0,0,0,0.00270097228009247,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN17",1.13375745347494e-05 "HALLMARK_COAGULATION2",0.0531330741087067,0.040956776475856,0.0851678627655442,6.81204203655228,27.5068073534066,26.5710752028332,1.92995744677694e-06,1.16507940706231e-06,0.00175927168278218,9.46670134377037e-05,7.05063975323843e-05,5.47218853013806e-05,5.47218853013806e-05,1.25632371281923e-06,2.66849736591298e-06,9.62230295442623e-12,0,0,0,0.00239451376291313,"HALLMARK_COAGULATION","kendall_tau","HN18","HN17",2.70067500582464e-11 "HALLMARK_HEDGEHOG_SIGNALING2",0.0580313852159569,0.043784028118017,0.099251009494707,7.21630753065358,32.6912700159513,23.4201436066567,1.45941790108715e-06,2.33855264903435e-06,0.0019488382565317,6.69759027062261e-05,0.000220818465960924,3.91004889170035e-05,3.91004889170035e-05,1.48980724647977e-06,5.50905831541436e-06,5.34239319449625e-13,0,0,0,0.0028127835052365,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN17",1.65769245296243e-12 "CELL_CYCLE2",0.0578870825417588,0.061377518391058,0.097244881717609,-2.23297521684107,34.8656047186194,21.3694664711139,1.31341517074861e-06,1.02996764441957e-06,0.00153081116247831,0.000122370508683021,0.000177831769250876,5.43230630961076e-05,5.43230630961076e-05,1.17428686498362e-06,2.71716020882688e-06,0.0255505787374439,0,0,0,0.00198093647215582,"CELL_CYCLE","kendall_tau","HN18","HN17",0.0328387766068132 "PEMT2",0.0815780726068496,0.0662761575411479,0.177512759630941,4.8757389881676,42.7009765331907,27.4484506170975,3.93465860359663e-06,5.81476184710602e-06,0.00312240619566107,0.000244264377401208,0.000789133112131662,0.000109312832039155,0.000109312832039155,4.94749284492016e-06,1.63232747565198e-05,1.08401866172336e-06,0,0,0,0.005026173314253,"PEMT","kendall_tau","HN18","HN17",2.00441186507339e-06 "EPI_DIFF12",0.0801683328661746,0.0464511765904416,0.146717875726967,10.1879054926713,30.9733966918824,28.2502288592955,8.02719809314447e-06,2.82577605145866e-06,0.00329438524532319,0.000818723204505118,0.00033370821656558,0.00036294866264812,0.00036294866264812,4.51649621241614e-06,1.24970686105996e-05,0,0,0,0,0.00547699360258202,"EPI_DIFF1","kendall_tau","HN18","HN17",0 "EPI_DIFF22",0.0857198812378668,0.0693842542585289,0.129412602212602,6.5877097659758,29.0323571780785,23.7201972965464,3.54320841508303e-06,2.50576621433529e-06,0.00245946633020628,0.000229060071543816,0.000315454498869373,0.000138962276428071,0.000138962276428071,2.16492375201199e-06,6.30436666709356e-06,4.46662706821144e-11,0,0,0,0.00344242594662135,"EPI_DIFF2","kendall_tau","HN18","HN17",1.1724896054055e-10 "STRESS2",0.0672910861296235,0.0547433255313161,0.132279234896529,4.54048382711094,37.0490677906256,25.7470705390567,4.14499835610827e-06,3.39209645168668e-06,0.0027453769882832,0.000213036476198074,0.00036313167175301,0.000132656432422124,0.000132656432422124,2.97690269363169e-06,8.96880625736137e-06,5.61252841912996e-06,0,0,0,0.00379405980475127,"STRESS","kendall_tau","HN18","HN17",9.62147728993707e-06 "HYPOXIA2",0.0665299936038447,0.0544872438607883,0.129590707856014,5.23152182767876,32.8826665068114,27.8548178664622,2.8492370719842e-06,2.34977903528932e-06,0.00228013510724113,0.000181260847292423,0.000396879937215412,6.1910138197797e-05,6.1910138197797e-05,3.57776279483193e-06,7.16974689521334e-06,1.68120178445363e-07,0,0,0,0.00355620523766275,"HYPOXIA","kendall_tau","HN18","HN17",3.35100559070758e-07 "HALLMARK_PANCREAS_BETA_CELLS3",0.0711541191757019,0.0480557469590371,0.0776891387185505,7.11652611106453,4.10649678303345,8.96388501600929,2.7798445003134e-06,7.65496427001669e-06,0.00323029546176973,0.00044226641943389,1.67522789038289e-05,0.000127650526997242,0.000127650526997242,2.43250789217906e-06,1.08287419385687e-05,1.10689235555128e-12,4.01705053874046e-05,0,0,0.00303992199124236,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN22",3.35491085084615e-12 "HALLMARK_MYOGENESIS3",0.0517935644305804,0.0420113457187662,0.0672618992320546,3.5839909521284,12.3360138411875,8.78367655780526,1.85540433717388e-06,5.49433243928768e-06,0.00271103979617813,0.000195362942632111,8.76623824649656e-05,8.80321855951083e-05,8.80321855951083e-05,1.47230730086205e-06,8.16397766318243e-06,0.000338383811736342,0,0,0,0.00225189087996133,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN22",0.000502448690153963 "HALLMARK_IL2_STAT5_SIGNALING3",0.047849951194823,0.0368007893047348,0.0612237734289696,4.60905214294315,8.24037967896202,8.90877807921441,1.323341741666e-06,4.32358195375476e-06,0.00237632567116142,0.000230017270516318,9.45820695064095e-05,4.29493481779453e-05,4.29493481779453e-05,2.53400531847496e-06,7.41555700126512e-06,4.04508883433685e-06,2.22044604925031e-16,0,0,0.00206685307562553,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN22",7.01626027902675e-06 "HALLMARK_ESTROGEN_RESPONSE_EARLY3",0.0549660610348763,0.0417217049497595,0.0758676983356157,4.25108262419212,11.9153285520186,9.94272862811491,1.99671460451586e-06,7.60978419487775e-06,0.00309943523878038,0.000345106244453979,0.000137196320334426,9.23132051334208e-05,9.23132051334208e-05,2.97714931600054e-06,1.16941957464005e-05,2.12739662068806e-05,0,0,0,0.00267881395826812,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN22",3.46992846869509e-05 "HALLMARK_BILE_ACID_METABOLISM3",0.054052772674304,0.0435580324663076,0.0680309044467208,4.06366622834871,8.49701935945149,8.24991911583202,1.8903230215468e-06,4.67939272334531e-06,0.00256314567375561,0.000304904567131803,0.000117654510551755,8.57735909900758e-05,8.57735909900758e-05,2.60623212446721e-06,8.69975327036222e-06,4.83078908197765e-05,0,2.22044604925031e-16,0,0.00241763554552266,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN22",7.63576338764209e-05 "HALLMARK_MITOTIC_SPINDLE3",0.0989643076637039,0.0753491428084734,0.111875659811663,5.38043387927496,3.1988466548324,6.64572478529889,3.55807105951202e-06,1.56059687047878e-05,0.00437767515518224,0.00122282626123753,0.000457979583257946,-1.75771044028626e-06,-1.75771044028626e-06,1.61913325788971e-05,3.01086849185523e-05,7.430652826379e-08,0.00137978538856176,3.01727531848428e-11,9.05182595545284e-11,0.00410905510686046,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN22",1.51973003892551e-07 "HALLMARK_INFLAMMATORY_RESPONSE3",0.0412617631535964,0.031602112600324,0.0524439606815773,4.73121316671708,10.1766527189549,10.2695841121286,1.46075757508481e-06,2.607723170317e-06,0.00201704753176563,0.000108223220906845,3.51949819119585e-05,4.97754435012173e-05,4.97754435012173e-05,1.10738120347673e-06,4.01876239854584e-06,2.23182005387734e-06,0,0,0,0.00169207724173274,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN22",3.98273199295866e-06 "HALLMARK_ESTROGEN_RESPONSE_LATE3",0.0676585006223306,0.0485605638218152,0.0838655145475276,5.41749640775571,7.51190864283663,9.01973204395028,2.29619863254597e-06,1.00310686637637e-05,0.00351102083393273,0.000514821022106958,0.000161346784725336,9.71074975913188e-05,9.71074975913188e-05,4.55484705024149e-06,1.52208883523544e-05,6.04393635139644e-08,5.81756864903582e-14,0,0,0.00313972315373198,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN22",1.24695949986705e-07 "HALLMARK_ADIPOGENESIS3",0.0439900925189429,0.0330938335475744,0.0532899596259226,5.33194610999387,6.69193698113319,8.75034097710518,1.00514681803277e-06,3.07107281222877e-06,0.00201896498985533,0.000167855693674479,6.9837553325295e-05,3.35890096087575e-05,3.35890096087575e-05,1.831300265754e-06,5.22704288599633e-06,9.7165776979935e-08,2.20234941394892e-11,0,0,0.00181747285930354,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN22",1.98036314953906e-07 "HALLMARK_P53_PATHWAY3",0.0601869212454875,0.0454389451888412,0.0763146917058281,4.8734122524194,8.70618399952657,8.88242204709676,1.89127302894954e-06,7.16668283262745e-06,0.00300964380975174,0.000385553816714619,0.000139338611203842,8.69599709103636e-05,8.69599709103636e-05,3.33157096437838e-06,1.1982926232445e-05,1.09686998683856e-06,0,0,0,0.00269561569206393,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN22",2.01549860081585e-06 "HALLMARK_HEME_METABOLISM3",0.0512313830199301,0.0378211023784354,0.0595313632990885,5.60602167211456,5.95537938877356,8.76786487040084,1.85146552307123e-06,3.77077605255961e-06,0.00237112664689823,0.000228576800943376,6.83869192988815e-05,7.7575827989289e-05,7.7575827989289e-05,1.84238472422391e-06,6.03115633604722e-06,2.07030050880519e-08,2.59469201679963e-09,0,0,0.0022764281839405,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN22",4.44283466853084e-08 "HALLMARK_CHOLESTEROL_HOMEOSTASIS3",0.0494624007780606,0.0424846473959409,0.0697780333903276,2.71010067782336,9.66284184830788,8.50308604897496,1.08476188910935e-06,5.44442682290112e-06,0.00255522772214346,0.000243580776353003,0.000226117790437573,1.41568732062278e-05,1.41568732062278e-05,4.32029198521397e-06,1.02029522333334e-05,0.00672627877645704,0,0,0,0.00216393450140177,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN22",0.00898875436490168 "HALLMARK_NOTCH_SIGNALING3",0.0414518615522329,0.0303404303219374,0.0554483890330326,4.02241919791937,7.80222579351858,10.1824872365265,3.53267187667541e-06,3.99804513530041e-06,0.00274421519053733,0.000147463973857084,5.11713637156561e-05,6.64253629726408e-05,6.64253629726408e-05,3.11812992194599e-06,5.98016076881161e-06,5.76034184944785e-05,5.99520433297585e-15,0,0,0.00211328492844777,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN22",9.02018910113271e-05 "HALLMARK_ALLOGRAFT_REJECTION3",0.0422240911173675,0.0340806200565269,0.0482110856038322,4.41715837652322,5.34024398351479,8.64655696227382,1.42421552260244e-06,1.8746436659711e-06,0.00181627618730565,7.9100974409242e-05,4.63520406953168e-05,4.27647676413297e-05,4.27647676413297e-05,1.15688492564993e-06,2.57070873727648e-06,1.00006954451004e-05,9.28215746487382e-08,0,0,0.00165094524820022,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN22",1.68252043539887e-05 "HALLMARK_INTERFERON_GAMMA_RESPONSE3",0.0391233728413272,0.0290458811082174,0.0507568782046497,5.1325145902982,10.8366851815997,10.5131431707388,1.17568157727159e-06,2.5794971410895e-06,0.00193782835110881,0.000113947101926885,3.45324597157931e-05,4.29559122274441e-05,4.29559122274441e-05,1.05246640735845e-06,4.16475788618844e-06,2.85896557761234e-07,0,0,0,0.00162467324264634,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN22",5.58495601207992e-07 "HALLMARK_ANDROGEN_RESPONSE3",0.0489756766015759,0.0374515414794577,0.0618893011750155,4.61823497616539,8.91110100304964,8.9216470407021,1.21150725634067e-06,4.91528865310397e-06,0.00247523653605966,0.000225974306177463,7.75966878770922e-05,5.17164680374584e-05,5.17164680374584e-05,2.00006907819426e-06,7.40296126916256e-06,3.8701786135853e-06,0,0,0,0.00212758707408844,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN22",6.74285550746371e-06 "HALLMARK_TNFA_SIGNALING_VIA_NFKB3",0.0500721696870788,0.0380961279836012,0.0684149860949405,4.38121217278303,12.3616384448263,10.4046164431148,2.02080087060055e-06,5.35121916971442e-06,0.00271514641231646,0.000199207668226837,8.82829779771301e-05,7.29321572076054e-05,7.29321572076054e-05,2.10181063080293e-06,8.39128721975858e-06,1.18020874440017e-05,0,0,0,0.00219349847824242,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN22",1.96590011815099e-05 "HALLMARK_PEROXISOME3",0.048178841278776,0.0377547296106296,0.0601020191057577,4.76535440903858,7.13929044743354,8.29391753538287,8.93880950684247e-07,3.7911824798885e-06,0.00216450073471291,0.00027772057348448,0.000123617003027941,4.29532034395227e-05,4.29532034395227e-05,2.6891632935025e-06,7.15989407461049e-06,1.88521983335299e-06,9.38138455808257e-13,0,0,0.00217459941927441,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN22",3.36932906386492e-06 "HALLMARK_INTERFERON_ALPHA_RESPONSE3",0.0531607932596956,0.0372582289083985,0.0639544699142526,6.14164047496861,8.19102307041817,10.5898472121582,2.20933565659613e-06,4.39515120262435e-06,0.00256991962115948,0.000176723036294115,6.57677105001522e-05,8.35751695932737e-05,8.35751695932737e-05,1.63645090645344e-06,6.25507733987475e-06,8.16735568065496e-10,2.22044604925031e-16,0,0,0.00229901102478636,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN22",1.95617317320779e-09 "HALLMARK_TGF_BETA_SIGNALING3",0.0496919984228251,0.0323103764477756,0.0562952644370117,7.0966385436595,4.93927361438285,10.0723091035933,2.01612914894066e-06,3.8828206755302e-06,0.00242877537546618,0.000191771906064712,4.81827525997233e-05,7.36242643311642e-05,7.36242643311642e-05,1.68727514918243e-06,5.57044704464709e-06,1.27831079055341e-12,7.84141203524769e-07,0,0,0.00228180814504699,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN22",3.86450768558047e-12 "HALLMARK_FATTY_ACID_METABOLISM3",0.0428609711256576,0.032447008842743,0.0527012352953759,4.7819659500118,7.56544466132543,8.67717046330791,1.19709052420127e-06,3.4455372688468e-06,0.00215467579766611,0.000188565706415882,6.96294600414414e-05,5.3806450985443e-05,5.3806450985443e-05,1.59178276911249e-06,5.3484762743352e-06,1.73589087659742e-06,3.86357612569554e-14,0,0,0.00201382793360023,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN22",3.11665293263904e-06 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE3",0.0686224407126257,0.0517290058487894,0.0838978400240405,4.92286894077534,6.17973471955844,7.61247747605224,2.17793934535151e-06,9.49810345496811e-06,0.00341702250509411,0.000673792879033747,0.000232719625458116,0.000102770943476426,0.000102770943476426,6.01006005809902e-06,1.77574154574006e-05,8.52845718934958e-07,6.4209393357828e-10,2.68673971959288e-14,8.06021915877864e-14,0.00328440333620975,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN22",1.59197867534526e-06 "HALLMARK_MTORC1_SIGNALING3",0.0588455096654909,0.0474205881995077,0.0714340655860334,4.19442740870854,5.26728387914815,7.02725461214828,1.18647790972841e-06,6.13279047637927e-06,0.00270541464217736,0.000413342706402444,0.000227648274775446,1.54022998328238e-05,1.54022998328238e-05,5.61187081549246e-06,1.15772003322893e-05,2.73561738526329e-05,1.38457014298154e-07,2.10631512231885e-12,6.31894536695654e-12,0.00255638027295185,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN22",4.437360062165e-05 "HALLMARK_UV_RESPONSE_UP3",0.0548457837954904,0.0407477310721495,0.066578412680531,5.62838418514607,6.44151416403384,8.79732870440888,1.18522937821449e-06,4.98886132111835e-06,0.00248477176000792,0.00025119792004078,0.000137175529482083,3.20147352498475e-05,3.20147352498475e-05,3.21752905609066e-06,8.52124712117486e-06,1.81905575047381e-08,1.18287379891058e-10,0,0,0.00221484164332844,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN22",3.93961245406482e-08 "HALLMARK_ANGIOGENESIS3",0.0645841693991745,0.0434293491407863,0.0837609805827093,6.18680644664739,9.90639966250112,10.8270139630612,2.87379682223617e-06,8.71811740362774e-06,0.00340469003374227,0.000514717390428733,6.25903867052368e-05,0.000120014879088694,0.000120014879088694,3.64732270180004e-06,1.37763161502221e-05,6.13952666483897e-10,0,0,0,0.0030422357503789,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN22",1.48561385964005e-09 "HALLMARK_MYC_TARGETS_V13",0.0871747345320246,0.0713302600555415,0.102798666291551,4.05087645314613,4.2911194220612,6.89085776363659,4.4915514651811e-06,1.07072596481042e-05,0.00389856526343799,0.000737301133625178,0.000591034674777516,5.48745003208402e-05,5.48745003208402e-05,1.31568232069295e-05,2.07546509228154e-05,5.10261454058636e-05,1.77774672416309e-05,5.54578605260758e-12,1.66373581578227e-11,0.00387198699940758,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN22",8.04379986558922e-05 "HALLMARK_DNA_REPAIR3",0.0702076500637652,0.0568325963390769,0.0847044587065595,4.39462859353066,5.21566683689439,7.52185440287688,1.85066640922686e-06,7.31222805731788e-06,0.00302702733164812,0.000507953549810615,0.000343629398596417,2.593759614205e-05,2.593759614205e-05,7.62547388025602e-06,1.36303665700243e-05,1.10962303181417e-05,1.83157120359212e-07,5.39568389967826e-14,1.61870516990348e-13,0.00303232387130778,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN22",1.85357483723503e-05 "HALLMARK_KRAS_SIGNALING_UP3",0.0562201964591611,0.0422857685942802,0.0725648916487563,4.8312939666003,9.07262353756424,10.4543343497304,2.61800711560302e-06,5.6006142329224e-06,0.00286681379732368,0.000228816045580263,9.4014775668989e-05,6.63915283978054e-05,6.63915283978054e-05,3.14554676148263e-06,8.28868361111425e-06,1.3564854548509e-06,0,0,0,0.00236865800486593,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN22",2.47706039581468e-06 "HALLMARK_HYPOXIA3",0.0474225779462575,0.0358656907955244,0.0612274623417206,4.61198076035557,8.23908091273224,8.67650115381593,1.44545181290757e-06,4.73378368601892e-06,0.00248580681045943,0.000296079356363305,0.000111829630200697,6.27418793055787e-05,6.27418793055787e-05,2.70742402694571e-06,8.44417066661307e-06,3.98849919558408e-06,2.22044604925031e-16,0,0,0.00231405723870928,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN22",6.93857256509894e-06 "HALLMARK_SPERMATOGENESIS3",0.0637002379348352,0.0484391956441972,0.0726084726440132,5.50332161243015,5.73162339437381,8.2969495233879,1.96492996342039e-06,5.62493307005152e-06,0.00275497060482901,0.000322224439056943,8.34104885129895e-05,9.28145734343357e-05,9.28145734343357e-05,2.31561661917374e-06,8.38575370268049e-06,3.727016251176e-08,9.94739424164948e-09,0,0,0.00261552297253567,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN22",7.86888888937697e-08 "HALLMARK_OXIDATIVE_PHOSPHORYLATION3",0.0742550278774566,0.0562728269757935,0.0852381717115048,5.56123287745096,4.82038902990497,8.34762690093272,3.3168923042095e-06,7.03857691010271e-06,0.00321799148760717,0.000447788984993656,0.000224915398790017,0.000115989110694308,0.000115989110694308,5.09145583088157e-06,1.19401346405042e-05,2.67875457371503e-08,1.4327853949947e-06,0,0,0.00319198268178729,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN22",5.72766432488885e-08 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION3",0.0487361008537033,0.0393644336194575,0.0641647040725838,3.91127886694918,11.6609376835814,10.0868373591269,1.64744956827069e-06,3.99366423762949e-06,0.00237510290427598,0.000146103184908634,7.43362790771975e-05,5.82792346547393e-05,5.82792346547393e-05,1.65059737014819e-06,5.94509036512615e-06,9.18086922874206e-05,0,0,0,0.00196703123203369,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN22",0.000141503305543914 "HALLMARK_MYC_TARGETS_V23",0.0699540341799674,0.0540463132252193,0.0823580611918088,5.07689228248919,4.75552736118985,7.53892973717473,2.7904261257897e-06,6.92750611468053e-06,0.00311735981889647,0.000498725996910624,0.000326131316529551,8.36472752599278e-05,8.36472752599278e-05,6.7034318234353e-06,1.40030802004911e-05,3.83658229408113e-07,1.97929049550183e-06,4.72955008490317e-14,1.41886502547095e-13,0.00316581288207148,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN22",7.42075785828849e-07 "HALLMARK_E2F_TARGETS3",0.0818839205213523,0.063621740375399,0.0911289184472327,5.42408614931935,2.94722716803019,6.92943579804015,2.70900305564458e-06,8.52679466606864e-06,0.00335198414699611,0.000530617097026358,0.00034289116365511,-1.25733883851835e-05,-1.25733883851835e-05,9.73980319545246e-06,1.5657826963344e-05,5.82517840630459e-08,0.0032063755770686,4.22528678711842e-12,1.26758603613553e-11,0.00306640651370884,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN22",1.20393845444889e-07 "HALLMARK_IL6_JAK_STAT3_SIGNALING3",0.0391278087622696,0.0269314635998066,0.0436867850588511,6.56465613248833,4.81568048396146,10.4190399740252,1.35454998570499e-06,1.99716914284304e-06,0.00183077009166854,8.65661813964798e-05,1.57859305747088e-05,4.5825675511711e-05,4.5825675511711e-05,7.96229716981458e-07,2.4861286185204e-06,5.21531706709766e-11,1.466990996013e-06,0,0,0.00168216637992596,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN22",1.35690550241302e-10 "HALLMARK_PROTEIN_SECRETION3",0.0615663822325598,0.0456307143731712,0.0723553566163307,5.49095369314972,5.65215109304094,8.59988910682584,2.75297586250454e-06,5.56960087161897e-06,0.00288488764670715,0.000313865942432124,0.000171751306612499,0.000101309112932949,0.000101309112932949,3.54361765836823e-06,9.55690808722804e-06,3.9976916665907e-08,1.58452209131354e-08,0,0,0.00277788719306174,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN22",8.41017066173642e-08 "HALLMARK_UV_RESPONSE_DN3",0.047570105753559,0.0352100956537646,0.0609652893791549,4.81980267038904,9.83432119865865,9.52093939165847,1.74473847242352e-06,4.73152395225638e-06,0.002544850177256,0.000244974065439125,7.89965731575644e-05,8.41089832887246e-05,8.41089832887246e-05,1.75527616653409e-06,7.21762316222064e-06,1.4370028647015e-06,0,0,0,0.00234028650714919,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN22",2.60789408779161e-06 "HALLMARK_APOPTOSIS3",0.0519763665553804,0.0385908379564059,0.0665916009260847,5.01473632691227,8.96717839632854,9.15857280129713,1.51862488827442e-06,5.50621069516156e-06,0.00265044063948544,0.000278839472749334,0.00010802475126066,6.51583383412552e-05,6.51583383412552e-05,2.55643961715951e-06,9.24725577093281e-06,5.31062422259865e-07,0,0,0,0.00232780347460575,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN22",1.01545597803126e-06 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY3",0.0421074373486542,0.0325616252866878,0.0530796870089386,4.31689354407889,7.75884343191565,8.72197005911304,1.50901581340529e-06,3.28069394881796e-06,0.00218854055530695,0.00015118593874112,9.5524667791193e-05,5.22127846386694e-05,5.22127846386694e-05,1.89984982978907e-06,5.43405512516484e-06,1.58240427299283e-05,8.65973959207622e-15,0,0,0.00196761237874869,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN22",2.60266772732807e-05 "HALLMARK_COMPLEMENT3",0.0416732509125227,0.030843049723423,0.0529760386491694,5.1727597229566,8.66317091044929,9.68980788040367,1.16051034459902e-06,3.12306461555391e-06,0.00206967991731884,0.000147310589881454,6.61757087482076e-05,4.08310214745338e-05,4.08310214745338e-05,1.60222662303623e-06,5.11734794342142e-06,2.30661549638356e-07,0,0,0,0.00181082723038411,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN22",4.54368479689625e-07 "HALLMARK_APICAL_JUNCTION3",0.0467409813713996,0.0344037449746954,0.0600884072221853,5.22057459790445,9.70667171202303,9.73981473049323,1.37636455929085e-06,4.10832660081842e-06,0.00234194174993941,0.000213910291620108,6.18056642537248e-05,5.71491346415408e-05,5.71491346415408e-05,1.79083812525369e-06,6.85418638750488e-06,1.78368839476306e-07,0,0,0,0.00204002362382691,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN22",3.54327289229959e-07 "HALLMARK_GLYCOLYSIS3",0.0650122308992198,0.0467165364182854,0.0781638070181628,5.93957317245664,6.02405503155102,8.35581531465084,1.65978394950701e-06,7.72849239191954e-06,0.00306402942894264,0.000527414285420739,0.000170311562520462,7.67185398115895e-05,7.67185398115895e-05,4.66626016605059e-06,1.40640760765243e-05,2.85765100471735e-09,1.70100489249592e-09,0,0,0.00293897158610655,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN22",6.53812759055955e-09 "HALLMARK_PI3K_AKT_MTOR_SIGNALING3",0.0461640483531542,0.0346863386814961,0.0518514328808446,5.38109775438628,4.24565070733594,7.61405568664362,1.21044204211821e-06,3.23911072966883e-06,0.00210939630505674,0.000204796579156488,6.87436597574783e-05,5.44768233442317e-05,5.44768233442317e-05,1.69447189648884e-06,4.98229985363773e-06,7.40329757498159e-08,2.17959949164737e-05,2.66453525910038e-14,7.99360577730113e-14,0.00209012899142509,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN22",1.51677316170355e-07 "HALLMARK_G2M_CHECKPOINT3",0.0959076730001498,0.0742944461661677,0.106054118129664,5.29414314532463,2.58107770755648,6.34739864230375,3.41952979974642e-06,1.31471028576815e-05,0.00407021285161205,0.000970885433293808,0.000444079943598692,-4.43543635194193e-05,-4.43543635194193e-05,1.53534575128931e-05,2.49357419727265e-05,1.19575743084965e-07,0.00984924089965489,2.18986162536794e-10,6.56958487610382e-10,0.00373261578748857,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN22",2.42032829376797e-07 "HALLMARK_APICAL_SURFACE3",0.0565427754443983,0.035877267021045,0.0714788558129383,7.23538690821012,7.74779901330454,10.5405643975026,1.34281053446699e-06,6.71490711194871e-06,0.00283861192247473,0.000409948797575241,0.000134915127874813,6.25942431538634e-05,6.25942431538634e-05,3.61634985455633e-06,1.13080397953309e-05,4.6429526889824e-13,9.32587340685131e-15,0,0,0.00273332206944182,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN22",1.4638370944352e-12 "HALLMARK_XENOBIOTIC_METABOLISM3",0.0537185284077117,0.0422634537163814,0.068440855236567,4.45261616532471,8.32291614308573,8.71048774964938,1.42008825369807e-06,5.09849952751831e-06,0.00255315251820497,0.000292196232261679,0.000114995622799033,5.0560319886545e-05,5.0560319886545e-05,3.0289734016578e-06,8.93167123464954e-06,8.48303190625899e-06,0,0,0,0.00226486271648403,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN22",1.43592797685428e-05 "HALLMARK_WNT_BETA_CATENIN_SIGNALING3",0.055543579074023,0.0362668424128643,0.0683519400791675,5.92060472236015,7.28980384222975,10.4889465816734,3.97286748019251e-06,6.52784107414752e-06,0.00324047967966782,0.000372804098902936,9.98638119626156e-05,0.000157073417358812,0.000157073417358812,2.98713367355511e-06,9.25713691011473e-06,3.20759974137275e-09,3.10418357685194e-13,0,0,0.00313060569845476,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN22",7.26808727524923e-09 "HALLMARK_KRAS_SIGNALING_DN3",0.0656416687845207,0.054607160153672,0.0820863883728152,3.55491250700289,8.03180638328894,7.90594662230154,2.55639387131979e-06,6.97852727309232e-06,0.00308786676273639,0.000359751482259272,0.000213475317628029,9.89767542680237e-05,9.89767542680237e-05,4.09205028339651e-06,1.1980956102516e-05,0.000378104885968789,8.88178419700125e-16,2.66453525910038e-15,2.66453525910038e-15,0.00282235994846018,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN22",0.000557906331115803 "HALLMARK_COAGULATION3",0.0531330741087067,0.0407437596429873,0.0619965644050664,5.1130035130708,6.68903583725821,8.66973079416978,1.92995744677694e-06,3.84145204324344e-06,0.00240237580116442,0.000205030756483226,6.37598215029529e-05,7.96050332577377e-05,7.96050332577377e-05,1.65583014793145e-06,5.90926395408922e-06,3.17076399136695e-07,2.24644747248703e-11,0,0,0.0022275062806676,"HALLMARK_COAGULATION","kendall_tau","HN18","HN22",6.17354048650255e-07 "HALLMARK_HEDGEHOG_SIGNALING3",0.0580313852159569,0.045164386791606,0.0766738628224399,4.4988395025935,8.74520083925429,9.03615830403551,1.45941790108715e-06,6.62058571830363e-06,0.00284253471735892,0.0003741647348822,0.000190578278536877,4.51224923412891e-05,4.51224923412891e-05,4.44430722231709e-06,1.20594715618752e-05,6.83254145794621e-06,0,0,0,0.00252844354153929,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN22",1.16281747533209e-05 "CELL_CYCLE3",0.0578870825417588,0.0448368027231437,0.0665507354456934,5.72161148909922,6.1045871393384,9.28590823957966,1.31341517074861e-06,3.78897496774541e-06,0.00225884708169766,0.000127829952817496,0.000143206654163483,5.30517493239143e-05,5.30517493239143e-05,1.91413925778261e-06,5.36799615127383e-06,1.05518380699721e-08,1.03066755130499e-09,0,0,0.00216905436889906,"CELL_CYCLE","kendall_tau","HN18","HN22",2.31510477057596e-08 "PEMT3",0.0815780726068496,0.0597734070515726,0.108357239865643,5.10567600139805,10.2192962327117,9.76124514195966,3.93465860359663e-06,1.42039774073158e-05,0.0042589477586503,0.000712477927537399,0.000336184201541556,0.000177873478862531,0.000177873478862531,6.76676458524149e-06,2.4672686568988e-05,3.29614034955128e-07,0,0,0,0.00379207426907602,"PEMT","kendall_tau","HN18","HN22",6.39647038130743e-07 "EPI_DIFF13",0.0801683328661746,0.0533030921665019,0.104761037748433,5.21007738772282,10.4397252722323,10.0392674660623,8.02719809314447e-06,1.84612582303584e-05,0.00514669372738488,0.00117284048795783,0.000195713587293833,0.000441001051033493,0.000441001051033493,5.44925211452357e-06,2.61724658984656e-05,1.8876188012662e-07,0,0,0,0.005076387076113,"EPI_DIFF1","kendall_tau","HN18","HN22",3.73710388937551e-07 "EPI_DIFF23",0.0857198812378668,0.0587074275010466,0.099791013375047,6.65199592982103,5.32854547524249,8.55410150452478,3.54320841508303e-06,1.28469232228055e-05,0.004048472753754,0.00102965364765817,0.000265538369508191,0.000218958389246428,0.000218958389246428,6.87333821827447e-06,2.29668285138309e-05,2.89144264087327e-11,9.9002410713922e-08,0,0,0.00427145877737875,"EPI_DIFF2","kendall_tau","HN18","HN22",7.79893703134624e-11 "STRESS3",0.0672910861296235,0.0473715758738033,0.0889273824404578,5.12927384024413,10.4876738852711,10.3817203024996,4.14499835610827e-06,1.08365364877628e-05,0.00387059877071638,0.000472226210594293,0.000144641203775444,0.000160211011303912,0.000160211011303912,4.156057552304e-06,1.59222972145075e-05,2.90861975171808e-07,0,0,0,0.00332709034666983,"STRESS","kendall_tau","HN18","HN22",5.67253205310192e-07 "HYPOXIA3",0.0665299936038447,0.0503883995450113,0.086199687048598,4.77834818989312,9.20013241673322,9.56140465002083,2.8492370719842e-06,8.46211898902023e-06,0.00336323595083729,0.000434318934399398,0.000166971910932973,0.000100928961938123,0.000100928961938123,4.47095584999129e-06,1.39280231400688e-05,1.76741129043201e-06,0,0,0,0.00293954793108582,"HYPOXIA","kendall_tau","HN18","HN22",3.16840804504275e-06 "HALLMARK_PANCREAS_BETA_CELLS4",0.0711541191757019,0.0469384018164506,0.130224780529659,4.96063370635598,20.9522916922539,13.8644151607333,2.7798445003134e-06,2.09499533501288e-05,0.00487132403463804,0.000258979241073837,0.00012620227851334,-4.92154904440691e-06,-4.92154904440691e-06,7.84841626323634e-06,3.59865072651383e-05,7.02635773563998e-07,0,0,0,0.00486371815043956,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN28",1.3214614544687e-06 "HALLMARK_MYOGENESIS4",0.0517935644305804,0.0386590268415247,0.103078506644722,3.43737250691472,25.3414991363367,14.8344862689888,1.85540433717388e-06,1.26453864279999e-05,0.00380799038407056,5.61525680263832e-05,9.4709570814545e-05,1.9981719376682e-05,1.9981719376682e-05,3.99557737294778e-06,1.87577296454871e-05,0.000587387172847009,0,0,0,0.0044543772564085,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN28",0.000857031408521195 "HALLMARK_IL2_STAT5_SIGNALING4",0.047849951194823,0.0253116190709646,0.088533227986623,7.52291047496115,23.6820456467251,18.1298956840219,1.323341741666e-06,7.55242920943943e-06,0.00297922321270251,7.44601911692039e-05,5.27927479439839e-05,1.02082299902589e-05,1.02082299902589e-05,2.85116453464382e-06,1.20601932651362e-05,5.35127497869325e-14,0,0,0,0.00322947288287082,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN28",1.8188148482495e-13 "HALLMARK_ESTROGEN_RESPONSE_EARLY4",0.0549660610348763,0.0298062875352372,0.10786638331028,7.46474257862759,26.5112774428017,20.2947003667963,1.99671460451586e-06,9.26342798990488e-06,0.0033556135943253,0.000199456866295274,9.14189538271451e-05,6.19345365503923e-05,6.19345365503923e-05,3.88157890062077e-06,1.46942472341015e-05,8.34887714518118e-14,0,0,0,0.00450850923981954,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN28",2.82134469044054e-13 "HALLMARK_BILE_ACID_METABOLISM4",0.054052772674304,0.0274662946919044,0.0964850599105826,8.47238428104399,24.6890516818394,19.4164281605791,1.8903230215468e-06,7.85682180237724e-06,0.00312204177164945,3.75380729306686e-05,3.64968429008919e-05,6.8179559168189e-06,6.8179559168189e-06,2.85382027344993e-06,1.25355947880989e-05,0,0,0,0,0.00330279174665288,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN28",0 "HALLMARK_MITOTIC_SPINDLE4",0.0989643076637039,0.0398244882951342,0.128829382102148,14.4551665243481,21.964167950146,21.440083632666,3.55807105951202e-06,1.30803230487055e-05,0.00407901876781874,0.00029888389822099,4.63847071304722e-05,0.000177641006803475,0.000177641006803475,1.74883302981808e-06,1.71335529363637e-05,0,0,0,0,0.00386143056553577,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN28",0 "HALLMARK_INFLAMMATORY_RESPONSE4",0.0412617631535964,0.0292877915074263,0.0939841793347125,3.18325029426536,28.3155848735859,14.8028794384249,1.46075757508481e-06,1.25885398267357e-05,0.00374823924020607,3.0773996712273e-05,8.89032813024479e-05,1.68720561346796e-05,1.68720561346796e-05,3.36688580530406e-06,1.90015083622039e-05,0.00145631665738133,0,0,0,0.00445632368162598,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN28",0.00205597645747952 "HALLMARK_ESTROGEN_RESPONSE_LATE4",0.0676585006223306,0.0337243534746905,0.122731028837568,9.61987202155511,27.817416761831,21.2679706449951,2.29619863254597e-06,1.00470932534805e-05,0.00351330213417897,0.000189534851306137,0.00010319140641067,8.21565689044824e-05,8.21565689044824e-05,3.81955202988225e-06,1.74143108779558e-05,0,0,0,0,0.00454583196709328,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN28",0 "HALLMARK_ADIPOGENESIS4",0.0439900925189429,0.0239024390243902,0.0917547136785564,6.60091621337226,30.2931663284152,20.2084029033737,1.00514681803277e-06,8.15568455239219e-06,0.0030266865332282,3.80582282350477e-05,5.31645901111696e-05,6.56465165176003e-06,6.56465165176003e-06,2.38612714944602e-06,1.11736575554819e-05,4.08624245551437e-11,0,0,0,0.00366063542965494,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN28",1.08230205578489e-10 "HALLMARK_P53_PATHWAY4",0.0601869212454875,0.0312095845079054,0.124904058620629,7.2254563186927,33.1343856329005,19.5652698558379,1.89127302894954e-06,1.40924422171878e-05,0.00399796388754792,9.04607107951594e-05,8.27714249844527e-05,2.94475067326378e-05,2.94475067326378e-05,3.71487887150569e-06,2.28327571069507e-05,4.99378316476395e-13,0,0,0,0.00492650027152208,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN28",1.56605040046998e-12 "HALLMARK_HEME_METABOLISM4",0.0512313830199301,0.0262893736977571,0.098494318281302,7.68591134625412,28.7511544750004,19.8071465006371,1.85146552307123e-06,8.57959558686389e-06,0.00322971532955075,4.02721887742419e-05,3.71529905716997e-05,1.55054085692174e-05,1.55054085692174e-05,2.60228284265838e-06,1.31889311222499e-05,1.50990331349021e-14,0,0,0,0.00369567445433127,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN28",5.44676778117942e-14 "HALLMARK_CHOLESTEROL_HOMEOSTASIS4",0.0494624007780606,0.0266793689780659,0.111852688448078,7.17313992270981,30.080530804249,20.4488394566711,1.08476188910935e-06,8.90322310898626e-06,0.00316037735058578,3.26352064253053e-05,0.000134935133854715,1.42465694892378e-05,1.42465694892378e-05,4.20192648960805e-06,1.72488150091918e-05,7.32969240857528e-13,0,0,0,0.0047980079695398,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN28",2.26239324737127e-12 "HALLMARK_NOTCH_SIGNALING4",0.0414518615522329,0.0241787962234461,0.0843978307294594,4.67145383723324,18.9963092077293,18.367325830232,3.53267187667541e-06,1.00394118103095e-05,0.00368403090201276,7.12219716944287e-05,1.73453286880761e-05,-1.91291991418537e-05,-1.91291991418537e-05,5.01100559010159e-06,1.06491894136656e-05,2.99075318554998e-06,0,0,0,0.00394440961342215,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN28",5.28891089655154e-06 "HALLMARK_ALLOGRAFT_REJECTION4",0.0422240911173675,0.023572820941242,0.0712872434667777,6.8748040002411,20.8227122145315,16.6461725014709,1.42421552260244e-06,5.83609580121254e-06,0.00269449648799455,3.47303782947802e-05,1.29515028648207e-05,4.90286214139928e-06,4.90286214139928e-06,1.84809819158701e-06,8.11619167654166e-06,6.20747897528418e-12,0,0,0,0.00249600025584767,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN28",1.76328388283435e-11 "HALLMARK_INTERFERON_GAMMA_RESPONSE4",0.0391233728413272,0.0241889664686802,0.10189345685671,4.78535422464995,34.3324495541865,21.5799249653873,1.17568157727159e-06,8.46406702391754e-06,0.00310479445393558,4.37236198596921e-05,6.94782838339177e-05,-2.1035887535761e-06,-2.1035887535761e-06,3.24268797214656e-06,1.28655926379994e-05,1.70686033040823e-06,0,0,0,0.00494949825105743,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN28",3.06921674091756e-06 "HALLMARK_ANDROGEN_RESPONSE4",0.0489756766015759,0.0239950726779995,0.0979714919227114,8.65192026352428,25.3864578003818,21.6867378383673,1.21150725634067e-06,7.0249369991801e-06,0.00286992060090881,0.000169558985816805,8.33987340615322e-05,2.911529838448e-05,2.911529838448e-05,3.62489266610527e-06,1.15358510382747e-05,0,0,0,0,0.00391482501675195,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN28",0 "HALLMARK_TNFA_SIGNALING_VIA_NFKB4",0.0500721696870788,0.0342310332148548,0.115511818675258,3.64096853328154,27.4049849236755,16.5140908017943,2.02080087060055e-06,1.68086850490115e-05,0.00433929555568782,7.6059126587048e-05,0.000119423004500283,-4.37868693603863e-06,-4.37868693603863e-06,5.60194189457596e-06,2.41251484550395e-05,0.000271614335148884,0,0,0,0.00536687868564799,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN28",0.000405868434733276 "HALLMARK_PEROXISOME4",0.048178841278776,0.0219372901895781,0.0933416179637851,10.4586540648646,31.1946501540539,24.4616764586374,8.93880950684247e-07,5.30157815211407e-06,0.00248906791847838,5.54709130405166e-05,4.11564980920976e-05,1.04255099338769e-05,1.04255099338769e-05,1.99604707235655e-06,8.4207266758628e-06,0,0,0,0,0.00325366343702897,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN28",0 "HALLMARK_INTERFERON_ALPHA_RESPONSE4",0.0531607932596956,0.0345020673954166,0.133758909091199,4.24294519552423,33.5853709567546,20.701906348936,2.20933565659613e-06,1.70294466087196e-05,0.00438620362789004,6.31399900813817e-05,0.00011627111181756,-5.6985416839123e-06,-5.6985416839123e-06,5.65903183847011e-06,2.28879489965279e-05,2.20605323979495e-05,0,0,0,0.00641987092018351,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN28",3.59323907202058e-05 "HALLMARK_TGF_BETA_SIGNALING4",0.0496919984228251,0.0321453529000699,0.0972435883388483,4.16535213600835,25.6712709570585,14.7558435063167,2.01612914894066e-06,1.5629228657156e-05,0.00420063778563407,2.26461133918318e-05,6.34743279946948e-05,1.38224064139894e-05,1.38224064139894e-05,3.33111554553092e-06,1.93630255187663e-05,3.1087235604188e-05,0,0,0,0.00403211242080744,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN28",5.00117497544803e-05 "HALLMARK_FATTY_ACID_METABOLISM4",0.0428609711256576,0.0245431376751887,0.0954308570394765,6.2123309789357,33.983721280085,20.6919763297193,1.19709052420127e-06,7.39729793394906e-06,0.00293161874365517,2.90668738293903e-05,5.19779846503612e-05,1.32833612640345e-05,1.32833612640345e-05,2.29294216718975e-06,1.16364853933818e-05,5.22043297479513e-10,0,0,0,0.00410979324840866,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN28",1.27106194168925e-09 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE4",0.0686224407126257,0.031972172520953,0.131296875210203,8.37159481323694,28.6152457658525,22.292550801508,2.17793934535151e-06,1.68883444064149e-05,0.00436649559163483,0.000234317579858739,5.30722707189069e-05,1.57116180130468e-05,1.57116180130468e-05,4.69717859983157e-06,1.97515772218561e-05,0,0,0,0,0.00465655529594152,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN28",0 "HALLMARK_MTORC1_SIGNALING4",0.0588455096654909,0.0270704743228337,0.103007130600739,10.2899497468114,26.7261198270905,21.0876898112413,1.18647790972841e-06,8.24906834099525e-06,0.0030717334276795,0.000109808874126247,5.53050579248475e-05,2.41283595591359e-05,2.41283595591359e-05,2.63034916076612e-06,1.28671618159099e-05,0,0,0,0,0.00325414754325327,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN28",0 "HALLMARK_UV_RESPONSE_UP4",0.0548457837954904,0.0291982997333115,0.103099534499445,8.60708124196212,28.5108960434559,21.1954096692994,1.18522937821449e-06,7.59405024111176e-06,0.00296298491716145,4.38685460155824e-05,8.52506638504419e-05,2.8469562532339e-05,2.8469562532339e-05,2.76444454727322e-06,1.20568136452138e-05,0,0,0,0,0.00374543283582165,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN28",0 "HALLMARK_ANGIOGENESIS4",0.0645841693991745,0.0353735965931088,0.112003899120624,5.39225826218917,22.3203298614713,15.4971083855123,2.87379682223617e-06,2.63715183083295e-05,0.0054078937795195,0.000145270910253119,8.57303449918641e-05,5.56112896354915e-05,5.56112896354915e-05,4.41353621579336e-06,2.43511752989237e-05,6.9577668293519e-08,0,0,0,0.00432970522668491,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN28",1.42798146445337e-07 "HALLMARK_MYC_TARGETS_V14",0.0871747345320246,0.0414086941234876,0.156904684086324,10.2284576656991,26.7381969304318,24.1699683910372,4.4915514651811e-06,1.54285546639395e-05,0.00446319461026748,0.000143987749647835,9.04110056088384e-05,3.58454380609049e-05,3.58454380609049e-05,6.70102649633271e-06,2.2733981589307e-05,0,0,0,0,0.00535171441368241,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN28",0 "HALLMARK_DNA_REPAIR4",0.0702076500637652,0.0348584342486781,0.144829763732203,9.67472393774901,31.1429874591739,24.6020700332036,1.85066640922686e-06,1.13993686020456e-05,0.00364005975380521,7.77966418988828e-05,0.000144802700273294,1.03870517337273e-05,1.03870517337273e-05,5.64135697922408e-06,1.9880927775308e-05,0,0,0,0,0.00546600946502938,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN28",0 "HALLMARK_KRAS_SIGNALING_UP4",0.0562201964591611,0.0337291285201568,0.105647774825983,5.99779372723639,23.243593308494,19.2309826731907,2.61800711560302e-06,1.13436694209851e-05,0.0037365326890833,0.000102442925052263,5.31220007128266e-05,7.81845657256072e-06,7.81845657256072e-06,4.4220163750174e-06,1.38855662667063e-05,2.00016359030997e-09,0,0,0,0.00417813871599595,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN28",4.62120310845682e-09 "HALLMARK_HYPOXIA4",0.0474225779462575,0.0261233607059689,0.093625080979812,7.34456235211437,26.2166695145755,19.3577005472589,1.44545181290757e-06,6.86453746230574e-06,0.00288270520088567,0.0001062743415194,7.44525294821257e-05,3.5512814456423e-05,3.5512814456423e-05,3.00581776394234e-06,1.20596800360433e-05,2.06501482580279e-13,0,0,0,0.00384774784812378,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN28",6.72702890621629e-13 "HALLMARK_SPERMATOGENESIS4",0.0637002379348352,0.0357384592301152,0.131991891750282,6.92529703896319,35.6782526368365,21.290159250249,1.96492996342039e-06,1.42375162834665e-05,0.00402522623549123,0.000110984180806521,7.59909377038084e-05,3.66569845686553e-05,3.66569845686553e-05,3.56376920076203e-06,2.03397053997796e-05,4.35051994429614e-12,0,0,0,0.00526932100276287,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN28",1.27268941654036e-11 "HALLMARK_OXIDATIVE_PHOSPHORYLATION4",0.0742550278774566,0.0413519927798638,0.155777218723045,6.5150222277406,24.2626674107657,19.4352657624998,3.3168923042095e-06,2.20889762928089e-05,0.0050404234541374,0.000229842145244595,0.000275444789428668,1.70551655883488e-05,1.70551655883488e-05,1.11894970635392e-05,3.4562716088421e-05,7.26789739502465e-11,0,0,0,0.00655151541697494,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN28",1.87847194209868e-10 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION4",0.0487361008537033,0.0335881848265719,0.109971880307461,3.73777050204147,29.6902158383689,16.6403044107386,1.64744956827069e-06,1.46766100655566e-05,0.0040403043986595,7.41223263785364e-05,8.55084043574206e-05,3.80099071356586e-06,3.80099071356586e-06,4.15386586000136e-06,2.09706919675646e-05,0.00018565929638914,0,0,0,0.00498179029157156,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN28",0.000280997853994374 "HALLMARK_MYC_TARGETS_V24",0.0699540341799674,0.0362341935579065,0.142424817299767,7.98563781394162,32.7060301260579,22.0656159555318,2.7904261257897e-06,1.4939592976788e-05,0.00421070292262203,7.80188740036047e-05,8.3846519849079e-05,2.04003812423383e-05,2.04003812423383e-05,4.80987283123836e-06,2.30600894923465e-05,1.33226762955019e-15,0,0,0,0.00546507222894215,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN28",5.27524152306741e-15 "HALLMARK_E2F_TARGETS4",0.0818839205213523,0.0366073407193643,0.122964702971444,13.250260815486,22.8237457537948,23.0820176917843,2.70900305564458e-06,8.86711215695736e-06,0.00340236905884737,0.000152992403067544,9.64414699556708e-05,0.000105502111359812,0.000105502111359812,3.13969087037524e-06,1.3897523262633e-05,0,0,0,0,0.00375530770999034,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN28",0 "HALLMARK_IL6_JAK_STAT3_SIGNALING4",0.0391278087622696,0.0234080492368677,0.0811842265804947,6.24318969383257,24.3660076405764,19.0567642028021,1.35454998570499e-06,4.88529639327405e-06,0.00249796845035702,4.34617536586778e-05,5.69142860372702e-05,6.08897940845106e-06,6.08897940845106e-06,2.87917356100772e-06,9.0917729410996e-06,4.28736379731731e-10,0,0,0,0.0034848083605326,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN28",1.04822033797197e-09 "HALLMARK_PROTEIN_SECRETION4",0.0615663822325598,0.033604514334617,0.124605473286876,5.92526833244134,31.3124639471245,19.8507114915323,2.75297586250454e-06,1.94168239937245e-05,0.00470848169330932,4.82256178054342e-05,4.84550009034034e-05,1.14167120337716e-05,1.14167120337716e-05,3.95308207904823e-06,2.09155026964431e-05,3.11787839990529e-09,0,0,0,0.004939821191116,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN28",7.09211798508438e-09 "HALLMARK_UV_RESPONSE_DN4",0.047570105753559,0.0257200286163701,0.0988766484193313,6.44337123717251,30.1473035877753,20.6515456902692,1.74473847242352e-06,9.65477961815881e-06,0.00337631723784693,7.4896326662615e-05,4.56789775183791e-05,2.09125084326637e-05,2.09125084326637e-05,2.79633339625339e-06,1.2448798230111e-05,1.16848308806539e-10,0,0,0,0.00412177497875317,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN28",2.98725241644542e-10 "HALLMARK_APOPTOSIS4",0.0519763665553804,0.026967788971368,0.108039041703638,6.87842716480673,31.9626272758338,19.9778331730546,1.51862488827442e-06,1.16004083982663e-05,0.00362202060824352,8.86673506199573e-05,6.01169980379568e-05,2.2459165682177e-05,2.2459165682177e-05,2.97654090375442e-06,1.63678538260916e-05,6.0516036626268e-12,0,0,0,0.00432649312768102,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN28",1.72735094836144e-11 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY4",0.0421074373486542,0.0262855079984657,0.0932696367732807,5.30304316016846,28.7649867789352,18.8788130402542,1.50901581340529e-06,7.29259409276332e-06,0.00296675073205833,4.24373622804793e-05,6.24723401621528e-05,9.53187552489229e-06,9.53187552489229e-06,3.06351614269427e-06,1.24890933822512e-05,1.13887981489924e-07,0,0,0,0.00416700105886389,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN28",2.3091770040026e-07 "HALLMARK_COMPLEMENT4",0.0416732509125227,0.0253900594532725,0.0872024854795913,4.97158720938841,29.9697741018738,17.5280745945573,1.16051034459902e-06,9.4667528130563e-06,0.00325994833665433,2.75334509713208e-05,5.05453534710015e-05,1.33737976582291e-05,1.33737976582291e-05,2.20788284630892e-06,1.23360698537013e-05,6.64069804034995e-07,0,0,0,0.00368285458949997,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN28",1.25352502334696e-06 "HALLMARK_APICAL_JUNCTION4",0.0467409813713996,0.0250232258855252,0.0965407087703325,6.75793877757618,30.3544031358625,19.8392677375552,1.37636455929085e-06,8.85128213344885e-06,0.00319806921325035,7.53023551977716e-05,3.36804621052979e-05,5.04395891178216e-06,5.04395891178216e-06,2.59160009871909e-06,1.28949066663283e-05,1.39968037160543e-11,0,0,0,0.00381295717116642,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN28",3.86390637795301e-11 "HALLMARK_GLYCOLYSIS4",0.0650122308992198,0.0281412606268594,0.104414719569763,11.4801637536055,24.6726817075479,21.5590492622789,1.65978394950701e-06,8.55530475236943e-06,0.00319610523948703,0.00014621377281604,3.37158642119435e-05,3.7662423132123e-05,3.7662423132123e-05,2.45043696021459e-06,1.24166374752158e-05,0,0,0,0,0.00306117277432809,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN28",0 "HALLMARK_PI3K_AKT_MTOR_SIGNALING4",0.0461640483531542,0.0243160904136514,0.0927736723207107,7.95402395018239,31.1435361500718,23.7783506982759,1.21044204211821e-06,6.23436111215978e-06,0.00272851665823722,2.88068037091679e-05,3.47528701881827e-05,4.34015321658203e-06,4.34015321658203e-06,2.13983152833807e-06,8.18857083551047e-06,1.77635683940025e-15,0,0,0,0.00352608252376382,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN28",6.94018486091261e-15 "HALLMARK_G2M_CHECKPOINT4",0.0959076730001498,0.0395772766270376,0.123376499220843,15.1708379018003,18.3842522876414,22.8693372612955,3.41952979974642e-06,1.02673655282113e-05,0.0036995804259345,0.000258287160082853,6.73460234746435e-05,0.000167108917730299,0.000167108917730299,2.13248351787848e-06,1.33268093078577e-05,0,0,0,0,0.0038022840783502,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN28",0 "HALLMARK_APICAL_SURFACE4",0.0565427754443983,0.0334734182436962,0.100910582610809,5.69684923209176,21.1752406011457,13.6048055724492,1.34281053446699e-06,1.49555917136083e-05,0.00403712797023766,0.000248666896969368,0.000102681326366922,4.6664682269373e-05,4.6664682269373e-05,4.29014861372412e-06,2.44704959036938e-05,1.22041758920943e-08,0,0,0,0.003838997673571,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN28",2.65779830538943e-08 "HALLMARK_XENOBIOTIC_METABOLISM4",0.0537185284077117,0.0284225395269028,0.0977967494265754,6.50560788691951,27.985588850629,16.3714812999188,1.42008825369807e-06,1.35990680360182e-05,0.00387545562349981,6.67163165392441e-05,4.17109809208067e-05,1.86636091411129e-05,1.86636091411129e-05,2.38072839444362e-06,1.78564362184972e-05,7.73798802811143e-11,0,0,0,0.00341979495932863,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN28",1.99558638619716e-10 "HALLMARK_WNT_BETA_CATENIN_SIGNALING4",0.055543579074023,0.0348460383558539,0.123854443621589,4.99596271720044,25.136873024942,18.2355349845836,3.97286748019251e-06,1.30903661319674e-05,0.00413076670996558,0.000271052769909434,9.51883270940614e-05,3.30929772504656e-05,3.30929772504656e-05,7.28511157259304e-06,2.37245673192003e-05,5.85429709376584e-07,0,0,0,0.00590620390255812,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN28",1.11042796488204e-06 "HALLMARK_KRAS_SIGNALING_DN4",0.0656416687845207,0.0437108519277465,0.129084560918939,5.01443130608083,27.6879358998151,18.3983339280501,2.55639387131979e-06,1.64714599390335e-05,0.00436209282459157,7.93872083420868e-05,0.000118943869074122,3.05972557728892e-05,3.05972557728892e-05,5.15030802909831e-06,2.14323437686482e-05,5.31905512302089e-07,0,0,0,0.00528294009928356,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN28",1.01545597803126e-06 "HALLMARK_COAGULATION4",0.0531330741087067,0.0327961859481197,0.108916126090814,4.65585330486309,26.2490646687569,15.7461298781337,1.92995744677694e-06,1.70496934511494e-05,0.0043565641161271,6.09844938272847e-05,6.66168654164835e-05,-1.49056607363154e-05,-1.49056607363154e-05,4.41623859067626e-06,2.32694890786775e-05,3.22641607142238e-06,0,0,0,0.00438228069388307,"HALLMARK_COAGULATION","kendall_tau","HN18","HN28",5.66308253730256e-06 "HALLMARK_HEDGEHOG_SIGNALING4",0.0580313852159569,0.026923549907768,0.101787837086054,9.41379946824647,21.6816585887014,19.4665904330245,1.45941790108715e-06,9.36025669110676e-06,0.00328932737686505,0.000108534709338264,7.30003855496392e-05,1.48070061205003e-06,1.48070061205003e-06,3.97285730168682e-06,1.46900487097105e-05,0,0,0,0,0.00326328872398449,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN28",0 "CELL_CYCLE4",0.0578870825417588,0.0310071446169007,0.0965472670960476,8.0763685719216,23.2582541738486,16.765158611526,1.31341517074861e-06,9.66363856839999e-06,0.00331316370545565,8.88883103938067e-05,7.72568667084354e-05,4.09392097630223e-05,4.09392097630223e-05,2.66295378820355e-06,1.51826674919862e-05,6.66133814775094e-16,0,0,0,0.00322447065840286,"CELL_CYCLE","kendall_tau","HN18","HN28",2.72004641033163e-15 "PEMT4",0.0815780726068496,0.0458758314855876,0.167313923204167,6.13171390696067,26.3535832554397,17.9314626287549,3.93465860359663e-06,2.98674874667844e-05,0.00581396130623356,0.000315588290690685,0.000265767783802825,7.6548692413499e-05,7.6548692413499e-05,1.04838962507917e-05,4.57646873472886e-05,8.69373462109024e-10,0,0,0,0.00700044297913654,"PEMT","kendall_tau","HN18","HN28",2.06960160210569e-09 "EPI_DIFF14",0.0801683328661746,0.0438669623059867,0.159622866293598,5.71608595615958,26.3376895618186,16.6497127097325,8.02719809314447e-06,3.22046889774485e-05,0.00634286111077588,0.000487551358996339,0.000237906657511899,0.000290901029362198,0.000290901029362198,9.00085122121332e-06,4.82362343440323e-05,1.09005613424529e-08,0,0,0,0.00769979755134785,"EPI_DIFF1","kendall_tau","HN18","HN28",2.38716203700644e-08 "EPI_DIFF24",0.0857198812378668,0.0392707563439271,0.152555397177348,10.0531930130418,29.504925867258,21.8209696733654,3.54320841508303e-06,1.77042920184445e-05,0.00460950110462374,0.000268038864316075,7.77274855995151e-05,8.12800080660248e-05,8.12800080660248e-05,5.03127811857835e-06,2.68521846103235e-05,0,0,0,0,0.00516138954030703,"EPI_DIFF2","kendall_tau","HN18","HN28",0 "STRESS4",0.0672910861296235,0.0341771307466914,0.151499144864311,6.32139701569326,29.9235573060881,20.1080698169573,4.14499835610827e-06,2.31957521030005e-05,0.00522883834700489,0.000245383967466581,9.52463450938079e-05,1.40570721503079e-05,1.40570721503079e-05,7.81919193565748e-06,3.39422495677328e-05,2.59209098629753e-10,0,0,0,0.00660583529898102,"STRESS","kendall_tau","HN18","HN28",6.43101054828249e-10 "HYPOXIA4",0.0665299936038447,0.0379901554117582,0.138285686991511,5.96898885018152,28.0096107196728,17.5981126189979,2.8492370719842e-06,1.99120921433109e-05,0.00477088348372659,0.000110644670930388,0.000170660956345221,4.68676675945776e-05,4.68676675945776e-05,6.46294228295392e-06,3.23811190878694e-05,2.38728414814204e-09,0,0,0,0.00580156653401978,"HYPOXIA","kendall_tau","HN18","HN28",5.49402379298443e-09 "HALLMARK_PANCREAS_BETA_CELLS5",0.0711541191757019,0.0771979577949727,0.0916035171632187,-1.97369694074788,9.43969285127429,7.40458009495208,2.7798445003134e-06,6.49717421781423e-06,0.00304581987617909,0.000142545390352494,0.000247492963605173,0.000101465250878121,0.000101465250878121,4.59294352195573e-06,3.68494334177968e-06,0.0484162132455133,0,1.31672450720544e-13,0,0.00357835648533741,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN18","HN5",0.0611573219943325 "HALLMARK_MYOGENESIS5",0.0517935644305804,0.0654073624567887,0.0754475602961503,-4.67668822952473,11.7752657912024,6.31853142112644,1.85540433717388e-06,6.51846511175364e-06,0.00289376388963017,9.60943048593588e-05,0.000220632237889115,6.64855517137483e-05,6.64855517137483e-05,3.935223513162e-06,2.42494685809494e-06,2.91544990171921e-06,0,2.64060551202761e-10,0,0.00347014183951049,"HALLMARK_MYOGENESIS","kendall_tau","HN18","HN5",5.17129575327571e-06 "HALLMARK_IL2_STAT5_SIGNALING5",0.047849951194823,0.0517924539022566,0.065741085491423,-1.75154723595383,9.16899468022386,9.62248689083647,1.323341741666e-06,3.64306779660824e-06,0.002228544264374,9.00257289231689e-05,0.000186275727178118,3.63714415688725e-05,3.63714415688725e-05,3.70743335172261e-06,2.00130237552339e-06,0.0798516922181887,0,0,0,0.00273643425771239,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN18","HN5",0.0982276046533367 "HALLMARK_ESTROGEN_RESPONSE_EARLY5",0.0549660610348763,0.0648329617331342,0.084943986992532,-3.61277323785557,12.4970442762601,10.5143920216861,1.99671460451586e-06,5.36227683191947e-06,0.00271274610615062,0.000211407349554582,0.000296500053499816,7.97262688270748e-05,7.97262688270748e-05,5.65424763910809e-06,3.5584750051636e-06,0.000302939613822328,0,0,0,0.00382176056414699,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN18","HN5",0.000451529766609706 "HALLMARK_BILE_ACID_METABOLISM5",0.054052772674304,0.0620953382147412,0.0708918092246984,-3.55562193161744,8.83810717963041,6.5165935013183,1.8903230215468e-06,3.12600128117243e-06,0.00223971522804111,0.000113369089486442,0.000170669646005313,6.0106634976193e-05,6.0106634976193e-05,3.53007795360604e-06,1.72211460652168e-06,0.000377086009386352,0,7.1922023892057e-11,0,0.002964087924643,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN18","HN5",0.000557101943515514 "HALLMARK_MITOTIC_SPINDLE5",0.0989643076637039,0.0868388982451834,0.109306538020593,3.23871345154394,4.34620582512189,8.63054582734287,3.55807105951202e-06,1.03586933251022e-05,0.00373051797805804,0.000287829616584049,0.000276050269307644,0.000146007929460156,0.000146007929460156,5.5624950380706e-06,6.6770139324573e-06,0.00120070138594164,1.38512602803065e-05,0,0,0.00384740609385468,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN18","HN5",0.00170947315964572 "HALLMARK_INFLAMMATORY_RESPONSE5",0.0412617631535964,0.0567048611476995,0.0649313933064777,-5.53838567921235,9.82419538826396,6.54575814917367,1.46075757508481e-06,6.21427940401712e-06,0.00277038570944588,4.9244520976187e-05,0.000335099668043218,3.88209153899984e-05,3.88209153899984e-05,5.70482272507794e-06,1.47947839363763e-06,3.05272414014013e-08,0,5.91942050931493e-11,0,0.00358883921618908,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN18","HN5",6.48015088231912e-08 "HALLMARK_ESTROGEN_RESPONSE_LATE5",0.0676585006223306,0.0690578628102066,0.0920503717950092,-0.479555256653874,9.34697438622865,11.4911851927668,2.29619863254597e-06,6.11876814022956e-06,0.00290085621373682,0.000241211156570838,0.000369870460532443,9.90350947239101e-05,9.90350947239101e-05,6.71001596503854e-06,3.90352995288273e-06,0.631543668232297,0,0,0,0.00385157880659897,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN18","HN5",0.667891505252861 "HALLMARK_ADIPOGENESIS5",0.0439900925189429,0.0564948200342657,0.0642268975820605,-5.43941393855194,7.73042337823538,6.29130385605438,1.00514681803277e-06,4.17984410437868e-06,0.00227705751407632,5.50599189224491e-05,0.000407219051020763,2.53183634043893e-05,2.53183634043893e-05,6.75294642553113e-06,1.41046643794927e-06,5.345612374974e-08,1.06581410364015e-14,3.14810399970611e-10,3.19744231092045e-14,0.0034325097039263,"HALLMARK_ADIPOGENESIS","kendall_tau","HN18","HN5",1.11461704839883e-07 "HALLMARK_P53_PATHWAY5",0.0601869212454875,0.0727310000931841,0.0876223977027997,-4.35930358742571,9.40357383971925,8.30184362010635,1.89127302894954e-06,6.28897451580594e-06,0.00286011320488464,0.000159143005830161,0.000487707250099991,6.63275926688859e-05,6.63275926688859e-05,8.41214739668495e-06,3.11752420408003e-06,1.30477000723772e-05,0,0,0,0.00414325524104,"HALLMARK_P53_PATHWAY","kendall_tau","HN18","HN5",2.15506956251624e-05 "HALLMARK_HEME_METABOLISM5",0.0512313830199301,0.0592759591717066,0.0688671341783545,-3.28791263071886,7.54226164358885,7.53602706222531,1.85146552307123e-06,4.03493537264672e-06,0.00242619061405281,8.23933383275284e-05,0.000307184556114942,5.80084590734247e-05,5.80084590734247e-05,5.3674489444314e-06,1.5197900700131e-06,0.001009331575202,4.61852778244065e-14,4.84057238736568e-14,1.3855583347322e-13,0.00332403312303657,"HALLMARK_HEME_METABOLISM","kendall_tau","HN18","HN5",0.00144752918589945 "HALLMARK_CHOLESTEROL_HOMEOSTASIS5",0.0494624007780606,0.0651818153351582,0.0769434679882441,-5.93393489722368,9.72762787930873,8.09944195066826,1.08476188910935e-06,5.83281501051664e-06,0.00263012868499357,8.41151949543739e-05,0.000459087446635682,2.29848508032505e-05,2.29848508032505e-05,7.88092612958561e-06,2.00875684314524e-06,2.95759150503727e-09,0,4.44089209850063e-16,0,0.00386342992017591,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN18","HN5",6.74055738357332e-09 "HALLMARK_NOTCH_SIGNALING5",0.0414518615522329,0.0555105703155775,0.0644985040236605,-5.01534959707701,9.6961900606911,7.98375910699308,3.53267187667541e-06,4.22490151981498e-06,0.0027852420714348,6.04945948667881e-05,0.000197670173926125,4.77938022564531e-05,4.77938022564531e-05,5.54954002177167e-06,1.16737422934424e-06,5.29371216195784e-07,0,1.33226762955019e-15,0,0.00348137562986802,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN18","HN5",1.01390969095479e-06 "HALLMARK_ALLOGRAFT_REJECTION5",0.0422240911173675,0.0463594283966109,0.0538340491123568,-2.04424136598917,6.98235473309582,7.09075545266339,1.42421552260244e-06,2.56799086294755e-06,0.00199805064639263,3.02358916087655e-05,0.000127090369349195,3.05303984436621e-05,3.05303984436621e-05,2.66476026287676e-06,1.0112027439286e-06,0.0409297084947631,2.90278912018493e-12,1.33382194178466e-12,4.00146582535399e-12,0.00232838704288625,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN18","HN5",0.0520360402052339 "HALLMARK_INTERFERON_GAMMA_RESPONSE5",0.0391233728413272,0.0575941779952491,0.0677798409644965,-7.22312490526211,9.08598949565773,7.32478586781123,1.17568157727159e-06,5.2634699967264e-06,0.00253754833924361,4.22807127733972e-05,0.000608569463237531,2.49764422090388e-05,2.49764422090388e-05,9.84720035094426e-06,1.83369839820179e-06,5.08038056068472e-13,0,2.39364084109184e-13,0,0.00422637077752972,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN18","HN5",1.58897009025671e-12 "HALLMARK_ANDROGEN_RESPONSE5",0.0489756766015759,0.0549615558570782,0.0733583166418987,-2.79434421785043,9.99257268022158,10.1742759093223,1.21150725634067e-06,3.27726071299114e-06,0.00211867127448592,0.000116298449108545,0.000339096122042245,4.37280946824561e-05,4.37280946824561e-05,5.85397248035863e-06,3.16945753412039e-06,0.0052005090302536,0,0,0,0.00330749436803663,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN18","HN5",0.00703774294542949 "HALLMARK_TNFA_SIGNALING_VIA_NFKB5",0.0500721696870788,0.0661883137987541,0.0834286035722322,-5.26171550513595,11.6262530579112,10.1008525450236,2.02080087060055e-06,7.26059709165276e-06,0.00304653868550086,9.6285837079468e-05,0.000457330313304454,4.91004184828047e-05,4.91004184828047e-05,8.13151332193918e-06,2.81321850433598e-06,1.42717479389987e-07,0,0,0,0.00425372372730494,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN18","HN5",2.85434958779973e-07 "HALLMARK_PEROXISOME5",0.048178841278776,0.0575408956291522,0.0674894070075502,-4.79252631897357,8.2731573761259,7.4015133751048,8.93880950684247e-07,2.82216242884905e-06,0.00192770417324165,8.59163462490434e-05,0.000318472182787078,3.19464526136919e-05,3.19464526136919e-05,5.34812951021596e-06,1.70665465932789e-06,1.64694158155676e-06,2.22044604925031e-16,1.34559030584569e-13,6.66133814775094e-16,0.00311184702497447,"HALLMARK_PEROXISOME","kendall_tau","HN18","HN5",2.97055720845207e-06 "HALLMARK_INTERFERON_ALPHA_RESPONSE5",0.0531607932596956,0.0781150713643364,0.0884382504576832,-6.6786281262787,7.94650934466864,6.28905251381542,2.20933565659613e-06,1.1651631241234e-05,0.00372303194961178,5.41159670047822e-05,0.00123713332941848,5.08406950791218e-05,5.08406950791218e-05,1.96079635485687e-05,2.59436532938918e-06,2.41189290761668e-11,1.99840144432528e-15,3.19409387827818e-10,5.99520433297585e-15,0.00586374237011406,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN18","HN5",6.56570847073428e-11 "HALLMARK_TGF_BETA_SIGNALING5",0.0496919984228251,0.0611446294352518,0.0687004480442949,-3.6681048471585,7.57268120053495,5.76192721241575,2.01612914894066e-06,7.63212976520771e-06,0.00310616466307702,7.68524530715287e-05,0.000358720137487404,6.0141588037483e-05,6.0141588037483e-05,6.20077605832057e-06,1.61960029605045e-06,0.0002443549846185,3.66373598126302e-14,8.31588620187063e-09,1.0991207943789e-13,0.00367965398309971,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN18","HN5",0.00036653247692775 "HALLMARK_FATTY_ACID_METABOLISM5",0.0428609711256576,0.0570226495369786,0.0643939916180263,-6.19050096092401,8.3401906711971,6.72727839271157,1.19709052420127e-06,3.93623639481641e-06,0.00226568464686012,5.60671100597069e-05,0.000402944928180157,3.66025194025342e-05,3.66025194025342e-05,6.56588701880075e-06,1.10064421096181e-06,5.99732929984498e-10,0,1.72866165826235e-11,0,0.00355618749794954,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN18","HN5",1.45419778486963e-09 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE5",0.0686224407126257,0.0826319874827337,0.09740703713918,-4.59470146454819,7.62838004158248,6.22821121069546,2.17793934535151e-06,7.0188624738375e-06,0.00303262292730056,0.000269077318920879,0.000812766352911533,7.3239004446014e-05,7.3239004446014e-05,1.41382182988464e-05,5.52770384015451e-06,4.33369254215776e-06,2.37587727269783e-14,4.71790828626695e-10,7.1276318180935e-14,0.00489021327707441,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN18","HN5",7.49473886702578e-06 "HALLMARK_MTORC1_SIGNALING5",0.0588455096654909,0.061613676705554,0.0762578055522816,-1.21220486149218,6.94169112180142,7.9676919042806,1.18647790972841e-06,3.92826069551633e-06,0.00226157878599105,0.000135142737665,0.000340335515680393,3.63832757302313e-05,3.63832757302313e-05,6.19189557743715e-06,3.27801845558588e-06,0.225433971016224,3.87423426673195e-12,1.55431223447522e-15,4.66293670342566e-15,0.0031326310977355,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN18","HN5",0.258392153913332 "HALLMARK_UV_RESPONSE_UP5",0.0548457837954904,0.0611758968042069,0.0761546909655445,-2.63269231993358,7.98303400454394,9.9656797842058,1.18522937821449e-06,4.49603344891963e-06,0.00238353997808598,8.61741673242166e-05,0.000424402759179231,3.88536266903222e-05,3.88536266903222e-05,7.02502506508106e-06,2.15912285234357e-06,0.00847110483572644,1.33226762955019e-15,0,0,0.00347453014105256,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN18","HN5",0.0112565189681517 "HALLMARK_ANGIOGENESIS5",0.0645841693991745,0.0828383335846022,0.0973639455782313,-4.72008788518108,10.8503493793774,7.47852075341052,2.87379682223617e-06,1.19824882664085e-05,0.00385438517647687,0.000207381603434168,0.000491734991541138,9.33623727753614e-05,9.33623727753614e-05,9.02692585657005e-06,3.67257143404345e-06,2.3574276715177e-06,0,7.52731210695856e-14,0,0.00477535444460066,"HALLMARK_ANGIOGENESIS","kendall_tau","HN18","HN5",4.1941527105973e-06 "HALLMARK_MYC_TARGETS_V15",0.0871747345320246,0.0969650733463011,0.111591704835911,-2.5642657015637,5.66429161327956,5.9010088557647,4.4915514651811e-06,9.98549024413857e-06,0.00380487078746699,0.000158633174188851,0.00107457708963979,0.000111339005776739,0.000111339005776739,1.84819951402405e-05,6.04378637710372e-06,0.0103394360206721,1.47633152369764e-08,3.61285512617826e-09,1.08385653785348e-08,0.00543906986362294,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN18","HN5",0.0136619963598993 "HALLMARK_DNA_REPAIR5",0.0702076500637652,0.0877431465966066,0.0994896272881347,-5.32032197488507,6.68087767675186,5.4364744951521,1.85066640922686e-06,8.91259684834324e-06,0.00328074126647776,0.00011230123300547,0.00118806324776623,4.46187917589186e-05,4.46187917589186e-05,1.91102827319613e-05,4.56853725109731e-06,1.03583766453141e-07,2.37514452550158e-11,5.43451141865603e-08,7.12543357650475e-11,0.00540228367963741,"HALLMARK_DNA_REPAIR","kendall_tau","HN18","HN5",2.10751746278364e-07 "HALLMARK_KRAS_SIGNALING_UP5",0.0562201964591611,0.0653632732002873,0.0832093123756665,-2.9907612680361,9.79748720129837,10.0810780996836,2.61800711560302e-06,6.62789513970758e-06,0.0030407075254471,0.00011939932327767,0.000352602268046833,4.35827058728518e-05,4.35827058728518e-05,7.48835967554291e-06,3.03378880962626e-06,0.00278282958067111,0,0,0,0.00377293521521355,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN18","HN5",0.00386833048093289 "HALLMARK_HYPOXIA5",0.0474225779462575,0.0532235578616738,0.0681541422464133,-2.57488802656598,8.79848970445589,8.6333831160822,1.44545181290757e-06,3.53013228631673e-06,0.00223060173478465,0.000154088812759236,0.000298255881832667,5.4099031316869e-05,5.4099031316869e-05,5.45197990656655e-06,2.89082901684997e-06,0.0100272542691329,0,0,0,0.00326910178100568,"HALLMARK_HYPOXIA","kendall_tau","HN18","HN5",0.0132793367347976 "HALLMARK_SPERMATOGENESIS5",0.0637002379348352,0.0783677152669511,0.0905138585463465,-4.8607701877595,7.76839780004968,7.65812774555891,1.96492996342039e-06,7.04050452976945e-06,0.00300090561217607,9.29744843235422e-05,0.000739386536384761,6.47820742795645e-05,6.47820742795645e-05,1.18137369609279e-05,2.41554208024113e-06,1.16929933180465e-06,7.99360577730113e-15,1.88737914186277e-14,2.39808173319034e-14,0.00462160313784622,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN18","HN5",2.14523559157921e-06 "HALLMARK_OXIDATIVE_PHOSPHORYLATION5",0.0742550278774566,0.106907470666565,0.113636945360863,-8.11057933630603,6.86563576516984,2.60467498970443,3.3168923042095e-06,1.27910394996577e-05,0.00401346879941369,0.000140616757569148,0.00206368649398966,8.11943562056151e-05,8.11943562056151e-05,3.28027499217553e-05,6.57506115309876e-06,4.44089209850063e-16,6.61959376202503e-12,0.00919614474916997,1.33226762955019e-15,0.00728706385293241,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN18","HN5",1.82604514260026e-15 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION5",0.0487361008537033,0.0669159456259134,0.0773785612497455,-6.17755458592748,10.9221777286998,8.24561093885625,1.64744956827069e-06,6.91313403065802e-06,0.00292584750096937,6.05956313361007e-05,0.000392849172282916,4.08326194636416e-05,4.08326194636416e-05,6.7770497178305e-06,1.51003331494641e-06,6.51020792830082e-10,0,2.22044604925031e-16,0,0.00397099127221191,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN18","HN5",1.57207485085868e-09 "HALLMARK_MYC_TARGETS_V25",0.0699540341799674,0.0865534287534992,0.0963518549332673,-4.8225602530018,6.4071809188314,4.74429623793142,2.7904261257897e-06,8.95714083484625e-06,0.00342747238656068,0.000119791965254527,0.00104319967050836,8.19533630565831e-05,8.19533630565831e-05,1.6874702697651e-05,4.16549121897999e-06,1.41727197622288e-06,1.48234979846507e-10,2.09232467640597e-06,4.4470493953952e-10,0.00529901882677971,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN18","HN5",2.58004929417663e-06 "HALLMARK_E2F_TARGETS5",0.0818839205213523,0.0770090188893841,0.0945516522112187,1.53220822485012,4.61035215975837,8.41596811259601,2.70900305564458e-06,7.31369155411933e-06,0.00316586395945308,0.000144182767325552,0.000437508463742752,9.86706071723501e-05,9.86706071723501e-05,7.44969683097586e-06,4.24491624315219e-06,0.125471059551097,4.01987429277106e-06,0,0,0.00377857844238532,"HALLMARK_E2F_TARGETS","kendall_tau","HN18","HN5",0.150105764020437 "HALLMARK_IL6_JAK_STAT3_SIGNALING5",0.0391278087622696,0.0438505148675229,0.0535515086954961,-2.06639544987215,7.31807284926682,8.88594280851997,1.35454998570499e-06,3.76887024376819e-06,0.00226349734470204,4.19823122244111e-05,0.00020281751247386,3.138901822818e-05,3.138901822818e-05,3.78472160406573e-06,1.09186050618988e-06,0.0387911552273252,2.5157653738006e-13,0,0,0.00269504333265363,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN18","HN5",0.0494240504304816 "HALLMARK_PROTEIN_SECRETION5",0.0615663822325598,0.0808002451855555,0.0898526516851831,-5.73291479600661,6.9464790849752,4.86214442118249,2.75297586250454e-06,8.40297166938518e-06,0.00334005202532681,8.71270727545136e-05,0.00102174300524599,7.50323510357587e-05,7.50323510357587e-05,1.64814262389873e-05,3.36634979774949e-06,9.8719230567923e-09,3.7452263512705e-12,1.16120848425716e-06,1.12356790538115e-11,0.0053136080563318,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN18","HN5",2.17404148216999e-08 "HALLMARK_UV_RESPONSE_DN5",0.047570105753559,0.0636038919621009,0.0731413901190021,-6.11418887620609,9.93272486476977,7.61817630549694,1.74473847242352e-06,5.03218950276032e-06,0.00260325334441038,9.14254266198367e-05,0.000386998756303056,5.76133321863988e-05,5.76133321863988e-05,6.52778286901222e-06,1.46735327486413e-06,9.70493019281093e-10,0,2.57571741713036e-14,0,0.00386600074493978,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN18","HN5",2.3056561427769e-09 "HALLMARK_APOPTOSIS5",0.0519763665553804,0.0625952675920229,0.077842583334437,-4.05870409821881,9.82020862491399,9.7227972266124,1.51862488827442e-06,5.22654713579274e-06,0.00259714690074843,0.000110914032272545,0.000397017326577489,4.89530243350548e-05,4.89530243350548e-05,6.83784187775356e-06,2.35925934702313e-06,4.93457939598763e-05,0,0,0,0.00371794080990884,"HALLMARK_APOPTOSIS","kendall_tau","HN18","HN5",7.7893494895053e-05 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY5",0.0421074373486542,0.0563217049057965,0.0640882247938318,-6.4066921436931,7.87247303528997,6.00571401926989,1.50901581340529e-06,3.3134335879525e-06,0.00219600760503187,5.64626799002673e-05,0.000454680392954644,3.50956698877626e-05,3.50956698877626e-05,7.69586176618224e-06,1.57233631739224e-06,1.48710599390256e-10,3.5527136788005e-15,1.90491711293816e-09,1.06581410364015e-14,0.00368358240342784,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN18","HN5",3.75286834512749e-10 "HALLMARK_COMPLEMENT5",0.0416732509125227,0.0525110057109235,0.0634921929548068,-4.72084709862612,9.30947525910309,9.17917861293036,1.16051034459902e-06,4.00983135030971e-06,0.00227383853756346,5.33587604049472e-05,0.000316238248692733,3.03983728566579e-05,3.03983728566579e-05,5.39309326981541e-06,1.33116910523224e-06,2.3486444722387e-06,0,0,0,0.00324930516162316,"HALLMARK_COMPLEMENT","kendall_tau","HN18","HN5",4.18485742326169e-06 "HALLMARK_APICAL_JUNCTION5",0.0467409813713996,0.0582602519608445,0.0694392377666584,-4.87405336573189,10.1964942963759,8.41423694628888,1.37636455929085e-06,4.10922989403823e-06,0.00234213459334196,9.20205919919094e-05,0.000264711431764961,3.95191948642888e-05,3.95191948642888e-05,4.85545154083915e-06,1.66512446388417e-06,1.09331434794413e-06,0,0,0,0.00326139213375822,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN18","HN5",2.01210903471408e-06 "HALLMARK_GLYCOLYSIS5",0.0650122308992198,0.0608712876224109,0.0809328458319683,1.73577661325262,7.05401969261066,10.1299733286382,1.65978394950701e-06,3.93150843606003e-06,0.00236459137813852,0.000196489757047049,0.000249628675403173,6.28330892458477e-05,6.28330892458477e-05,4.99385221823934e-06,3.82204634048244e-06,0.0826033408215501,1.73816516735315e-12,0,0,0.00303954127819248,"HALLMARK_GLYCOLYSIS","kendall_tau","HN18","HN5",0.101189092506399 "HALLMARK_PI3K_AKT_MTOR_SIGNALING5",0.0461640483531542,0.0595589319469917,0.0647168201379289,-5.86923693184274,6.65629562798747,4.11811001949609,1.21044204211821e-06,3.89808117381495e-06,0.0022602042420837,6.24735472027124e-05,0.000476338314632737,3.84102707783572e-05,3.84102707783572e-05,7.66877244111237e-06,1.46872911527977e-06,4.37805414144066e-09,2.80815370956589e-11,3.81992329812064e-05,8.42446112869766e-11,0.00364434921261494,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN18","HN5",9.80684127682707e-09 "HALLMARK_G2M_CHECKPOINT5",0.0959076730001498,0.0825236312726,0.103920492655174,3.72666836586484,3.36047093049358,8.7625122897997,3.41952979974642e-06,9.37878791000238e-06,0.00357747364906421,0.000221341621479281,0.000285846455082433,0.000128848404781588,0.000128848404781588,5.58552338921198e-06,5.86269872024687e-06,0.000194027480541203,0.000778097184557236,0,0,0.00371883424380799,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN18","HN5",0.000292533739892891 "HALLMARK_APICAL_SURFACE5",0.0565427754443983,0.0562548587066589,0.0753067004151697,0.10035531819771,8.50830301019381,8.24940737144445,1.34281053446699e-06,6.78819779436889e-06,0.00285149229857559,0.000306813706702992,0.00020084881849656,6.18953974796119e-05,6.18953974796119e-05,4.76364064257817e-06,5.23369807886011e-06,0.920062241535893,0,2.22044604925031e-16,0,0.00314704633123862,"HALLMARK_APICAL_SURFACE","kendall_tau","HN18","HN5",0.936790645927455 "HALLMARK_XENOBIOTIC_METABOLISM5",0.0537185284077117,0.0641057617349525,0.074263891418714,-4.17503257112613,9.66249356575024,7.24782226466216,1.42008825369807e-06,4.66976051773683e-06,0.00246776189520685,0.000107329145532927,0.000228003180295915,4.09011597523878e-05,4.09011597523878e-05,4.42115298488082e-06,1.86432089486164e-06,2.97943422182811e-05,0,4.23439061592035e-13,0,0.0031376239813226,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN18","HN5",4.79974608886283e-05 "HALLMARK_WNT_BETA_CATENIN_SIGNALING5",0.055543579074023,0.058516939113954,0.0798675859131421,-0.818665878976427,8.25710766893651,10.804390904241,3.97286748019251e-06,9.1182510028429e-06,0.00361816507128066,0.000226162599934184,0.000420602657834528,0.000115082529879637,0.000115082529879637,8.57789394977478e-06,3.80500410729231e-06,0.412977069105023,2.22044604925031e-16,0,0,0.00430758921019392,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN18","HN5",0.454313408108051 "HALLMARK_KRAS_SIGNALING_DN5",0.0656416687845207,0.0818373358338507,0.0941618981427385,-5.01190560041253,8.50321652845309,6.81631292356654,2.55639387131979e-06,7.78580391739811e-06,0.00321592875989471,0.000159003698769885,0.000654037716661653,8.06479641792266e-05,8.06479641792266e-05,1.11496639939404e-05,3.16921866642644e-06,5.38936429483883e-07,0,9.34075039538129e-12,0,0.00470330333145773,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN18","HN5",1.0270524359954e-06 "HALLMARK_COAGULATION5",0.0531330741087067,0.0676891897901491,0.0747732710580692,-4.96041399347658,8.08653225562761,5.75514307961712,1.92995744677694e-06,6.58107347569357e-06,0.00291736712164762,6.41442958498476e-05,0.000412184318911183,5.17558437234788e-05,5.17558437234788e-05,7.06139735633058e-06,1.41514717047541e-06,7.03431012327727e-07,6.66133814775094e-16,8.656844130428e-09,1.99840144432528e-15,0.00382466048164814,"HALLMARK_COAGULATION","kendall_tau","HN18","HN5",1.3214614544687e-06 "HALLMARK_HEDGEHOG_SIGNALING5",0.0580313852159569,0.0671964851069329,0.0794266363261723,-4.0840457733934,9.39048056694933,7.76010821161614,1.45941790108715e-06,3.4766688608745e-06,0.00222173057816686,9.43673640729425e-05,0.000268730916560414,3.68648965529501e-05,3.68648965529501e-05,5.09109694534668e-06,2.38386563566859e-06,4.42583068602787e-05,0,8.43769498715119e-15,0,0.0031398716829475,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN18","HN5",7.01452410615737e-05 "CELL_CYCLE5",0.0578870825417588,0.0620674405749033,0.0728230384872176,-1.73782727823715,7.53448280448888,8.93424471848189,1.31341517074861e-06,4.37305526359356e-06,0.00238463213815929,6.92902600547213e-05,0.000239003493706383,5.41052436636678e-05,5.41052436636678e-05,3.82969781901054e-06,1.34928376814326e-06,0.0822412525944007,4.90718576884319e-14,0,0,0.00294467432159586,"CELL_CYCLE","kendall_tau","HN18","HN5",0.100850587123061 "PEMT5",0.0815780726068496,0.105093906043703,0.122066690357735,-5.48056774746013,9.82547922644286,7.48306906713393,3.93465860359663e-06,1.4376013770484e-05,0.00427909714473516,0.000287011282930757,0.000975930413585027,0.000128451896608624,0.000128451896608624,1.68808105830373e-05,5.04454152823261e-06,4.23963133489025e-08,0,7.26085858104852e-14,0,0.00606625167758234,"PEMT","kendall_tau","HN18","HN5",8.90322580326952e-08 "EPI_DIFF15",0.0801683328661746,0.0925990798989442,0.120625885722901,-2.44288511905171,11.2159811833871,8.72777415044363,8.02719809314447e-06,1.77661595076965e-05,0.00507871613706072,0.000682380557532787,0.000694571792941058,0.00036248340431819,0.00036248340431819,1.29114194160837e-05,1.02119360345932e-05,0.0145703745284951,0,0,0,0.00650402292581259,"EPI_DIFF1","kendall_tau","HN18","HN5",0.0191022970407026 "EPI_DIFF25",0.0857198812378668,0.0922882374171384,0.112392657922509,-1.87352544253117,7.19010434346765,7.87897957603628,3.54320841508303e-06,8.64798915638878e-06,0.00349158954796692,0.000363039712359689,0.000802055524593592,0.00015560362204088,0.00015560362204088,1.36615094240645e-05,6.41093214714188e-06,0.0609958627803209,6.47482067961391e-13,3.33066907387547e-15,9.99200722162641e-15,0.00514882430387874,"EPI_DIFF2","kendall_tau","HN18","HN5",0.0762286234109005 "STRESS5",0.0672910861296235,0.0876117851916326,0.106208221314156,-5.1107846890428,10.3239100807326,8.77245116003477,4.14499835610827e-06,1.15639186087062e-05,0.00396344761095873,0.000242021269242488,0.000767600263529466,0.00011271636364467,0.00011271636364467,1.41099745263215e-05,4.39383919045504e-06,3.20823457355957e-07,0,0,0,0.00557050433287353,"STRESS","kendall_tau","HN18","HN5",6.23617166695215e-07 "HYPOXIA5",0.0665299936038447,0.0791745998181354,0.0982921113137379,-3.68663748918065,9.63951030367185,9.8363431984088,2.8492370719842e-06,8.81462022237343e-06,0.00341523898056309,0.000189969083195072,0.000599210815057675,8.37419131441992e-05,8.37419131441992e-05,1.07569780058327e-05,3.67742085352098e-06,0.000227236696233701,0,0,0,0.00468578009703585,"HYPOXIA","kendall_tau","HN18","HN5",0.000341726796382139 "HALLMARK_PANCREAS_BETA_CELLS6",0.0823560346341179,0.0666050356191201,0.0934286977749244,5.01928815699195,3.72006981794812,7.71672683923166,3.02596295134851e-06,6.72167220847496e-06,0.00312212029874306,0.000484297603397375,5.62994096269115e-05,-4.44303513089531e-05,-4.44303513089531e-05,8.7593527456477e-06,1.19828639858166e-05,5.18633036072913e-07,0.000199167712352954,1.19904086659517e-14,3.59712259978551e-14,0.0023232226713344,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN25","HN16",9.94963214391102e-07 "HALLMARK_MYOGENESIS6",0.0647154101784875,0.0476061393486547,0.0773793103630408,7.14235320695467,4.21056944934487,10.5587392043583,1.85978511114883e-06,3.7784766480423e-06,0.00237450242349658,0.000623684708761949,5.27246557474473e-05,-5.65875955249075e-05,-5.65875955249075e-05,8.94593135051503e-06,7.85107880088645e-06,9.17488307550229e-13,2.54727800390597e-05,0,0,0.00232933048094043,"HALLMARK_MYOGENESIS","kendall_tau","HN25","HN16",2.79524935150018e-12 "HALLMARK_IL2_STAT5_SIGNALING6",0.0519399686119973,0.0392525605896687,0.0602397339863074,6.14458640696926,3.70338181806089,11.3677927542824,1.78861908661645e-06,2.37482431639835e-06,0.00204045176444208,0.000249707236051463,4.33303683961385e-05,-2.21192884180474e-05,-2.21192884180474e-05,4.92267006785062e-06,3.30843963301509e-06,8.01721355969676e-10,0.000212744313362823,0,0,0.0018996887620602,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN25","HN16",1.92413125432722e-09 "HALLMARK_ESTROGEN_RESPONSE_EARLY6",0.0627816052544171,0.0438919749653701,0.0750741092470974,8.54023309725042,4.39891611429936,13.2418977549381,2.24865590309669e-06,2.54358086016867e-06,0.00218911780479383,0.000479168019711915,4.25950886225419e-05,-4.30281850329504e-05,-4.30281850329504e-05,7.70889090670448e-06,5.44512338901659e-06,0,1.08792865174401e-05,0,0,0.00222660530206155,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN25","HN16",0 "HALLMARK_BILE_ACID_METABOLISM6",0.0597841507040811,0.0458022264863311,0.0727361428893382,5.96089254314173,4.60028992568053,10.9210790611328,1.88447593338861e-06,3.51740645064396e-06,0.00232419499698983,0.000468556827924071,2.76255211902748e-05,-6.88970319119193e-05,-6.88970319119193e-05,7.82688834510723e-06,5.98230106726159e-06,2.50863907425014e-09,4.21903313752026e-06,0,0,0.00192850431559871,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN25","HN16",5.76203037366829e-09 "HALLMARK_MITOTIC_SPINDLE6",0.0896302041009672,0.0712586271397228,0.107823242235985,3.94745465530312,3.33438402068873,10.7281979542041,1.19394710012821e-05,9.62053501993632e-06,0.0046432753548781,0.000848653510838016,0.000462699991751473,-0.00016349405294889,-0.00016349405294889,2.96700269400756e-05,1.15163170084084e-05,7.89864719210609e-05,0.000854885429587338,0,0,0.00446030505398534,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN25","HN16",0.000122705536300089 "HALLMARK_INFLAMMATORY_RESPONSE6",0.0513563505526463,0.0377023217422396,0.0592643577293017,7.11819162793911,3.92125862864763,11.3569794672471,1.23969253897897e-06,2.3397521512775e-06,0.0018919420419919,0.000290909333317069,3.33313344239592e-05,-2.91352190028796e-06,-2.91352190028796e-06,3.96708393040258e-06,3.50457322052663e-06,1.09356967925578e-12,8.80876560735988e-05,0,0,0.00195929223495316,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN25","HN16",3.32309545944392e-12 "HALLMARK_ESTROGEN_RESPONSE_LATE6",0.0689556637412176,0.0496023578657877,0.0798939304468527,7.63415537792938,3.4922096307138,12.7122703318064,3.3750686159613e-06,2.951635883009e-06,0.00251529411778629,0.00047431543536969,6.6534649280056e-05,-6.22689665128878e-05,-6.22689665128878e-05,9.71061890021983e-06,5.57802631511753e-06,2.26485497023532e-14,0.000479042125406615,0,0,0.00241807513551949,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN25","HN16",7.97445941615789e-14 "HALLMARK_ADIPOGENESIS6",0.0553894195645162,0.0366311316354432,0.0628373240921666,9.98087815001266,3.05166666116946,12.6664947549288,1.30661850444153e-06,2.12561079217967e-06,0.00185262767350086,0.000408281739601531,2.67101908134511e-05,-3.77492179526669e-05,-3.77492179526669e-05,5.85653935574157e-06,4.18050449078607e-06,0,0.00227574672511066,0,0,0.00197040385302675,"HALLMARK_ADIPOGENESIS","kendall_tau","HN25","HN16",0 "HALLMARK_P53_PATHWAY6",0.0705628354994589,0.0493229325702962,0.0836270008862898,7.88727770307364,4.06028520258581,12.558580283791,2.64103915691134e-06,4.51084387945722e-06,0.00267430047608128,0.000632413661093884,5.91888355163947e-05,-6.89574048053461e-05,-6.89574048053461e-05,1.02526196552907e-05,7.36122547882944e-06,3.10862446895044e-15,4.90128094479125e-05,0,0,0.00252082788781391,"HALLMARK_P53_PATHWAY","kendall_tau","HN25","HN16",1.20254683404135e-14 "HALLMARK_HEME_METABOLISM6",0.0588376147373609,0.0419389300627888,0.0686133711441377,7.59375470199153,3.7561564717765,11.9330659834065,2.18405733866403e-06,2.66807994821904e-06,0.00220275674709739,0.00042721288947022,2.62999129535067e-05,-3.11841268048618e-05,-3.11841268048618e-05,6.6735039962987e-06,4.89673793444213e-06,3.10862446895044e-14,0.000172542838666745,0,0,0.0021681213927056,"HALLMARK_HEME_METABOLISM","kendall_tau","HN25","HN16",1.07206521275241e-13 "HALLMARK_CHOLESTEROL_HOMEOSTASIS6",0.0614800746083769,0.0406353709074141,0.0745290733498451,8.59702116747398,3.85294078679064,13.0701189247358,2.20697123746182e-06,3.57192046936416e-06,0.00240393255039029,0.000640662984574207,8.28036044790955e-05,-0.000107731977288568,-0.000107731977288568,1.13701661559946e-05,6.62479339865268e-06,0,0.000116707621398815,0,0,0.00231400784408762,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN25","HN16",0 "HALLMARK_NOTCH_SIGNALING6",0.0476969159176227,0.03798435775946,0.0579921058609723,4.50886998702287,4.39841888581863,10.3741916910256,1.95316249307428e-06,2.58698557733443e-06,0.002130762321426,0.000252007075400899,5.60837495771687e-05,-2.52908553146202e-05,-2.52908553146202e-05,5.37867518028855e-06,3.61952845056485e-06,6.51738312251737e-06,1.09042365685763e-05,0,0,0.00195129306466275,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN25","HN16",1.11240095095507e-05 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"HALLMARK_ANDROGEN_RESPONSE6",0.0563807528772179,0.0409881511289962,0.0643803602559121,7.95028674154657,3.40828946065574,12.6231595537869,1.62216301510025e-06,2.02634532091842e-06,0.00191010689125469,0.000300757164194575,4.12622910384644e-05,-3.2197363313018e-05,-3.2197363313018e-05,5.40889381580092e-06,3.33404777260856e-06,1.77635683940025e-15,0.000653715095396912,0,0,0.00189410589813981,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN25","HN16",6.94018486091261e-15 "HALLMARK_TNFA_SIGNALING_VIA_NFKB6",0.0641557580292891,0.0432197203320425,0.0761926777042665,9.05771121474061,4.17317702740777,13.1070546811209,2.06009559094493e-06,3.18249682313687e-06,0.00228967080910811,0.000531496817141366,5.82135191071614e-05,-4.59988260299278e-05,-4.59988260299278e-05,8.21949775301095e-06,6.22856987701854e-06,0,3.00381362867697e-05,0,0,0.00235047543150727,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN25","HN16",0 "HALLMARK_PEROXISOME6",0.0539081472017112,0.040062802093352,0.0648196726008714,6.26897399966597,4.04503249124339,11.4594670011255,1.96603510242372e-06,2.81165981892086e-06,0.00218579388812042,0.000373769936872183,3.52051015807065e-05,-6.44996867985312e-05,-6.44996867985312e-05,7.17657327569706e-06,4.56726707734165e-06,3.63434837780119e-10,5.23158679208713e-05,0,0,0.00183666165653195,"HALLMARK_PEROXISOME","kendall_tau","HN25","HN16",8.92274257263924e-10 "HALLMARK_INTERFERON_ALPHA_RESPONSE6",0.0754280213897922,0.0422965153078158,0.0849052320733183,13.8963029322618,2.60606427038976,13.7073684351951,2.20084483726825e-06,3.38354443073285e-06,0.00236313124222949,0.00100713248114783,4.83160621404591e-05,-9.13741106611148e-05,-9.13741106611148e-05,1.31248521860252e-05,9.56248287925374e-06,0,0.00915892739889279,0,0,0.00295479680580296,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN25","HN16",0 "HALLMARK_TGF_BETA_SIGNALING6",0.061045672474625,0.0372656624583279,0.0714904013607811,10.3260634119538,3.43834008789011,13.2331684506264,2.29769434694243e-06,2.90570695637353e-06,0.00228109651337158,0.000646620451694958,5.65433200295021e-05,-4.04734741845303e-05,-4.04734741845303e-05,9.12776830350139e-06,6.58886769189481e-06,0,0.000585292116968228,0,0,0.00262313589756353,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN25","HN16",0 "HALLMARK_FATTY_ACID_METABOLISM6",0.0562917719677744,0.0348902736746205,0.0659603111272336,11.660919260706,3.30537846183816,13.10537185586,1.23362848770465e-06,2.03476470509329e-06,0.00180786979420475,0.000566733546911835,2.94035007737947e-05,-8.63982253135049e-05,-8.63982253135049e-05,8.456168631016e-06,5.52062818691402e-06,0,0.000948482301466269,0,0,0.00190809719078502,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN25","HN16",0 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE6",0.0829681281229929,0.0551920273248241,0.0955509174449683,9.64286546425552,3.20419441816761,12.4594358985176,3.68071812420573e-06,4.51645866706696e-06,0.00286307121659114,0.000985908215730497,4.35596837530389e-05,-0.000122923855566926,-0.000122923855566926,1.53211276176658e-05,1.03925650149067e-05,0,0.00135440982920243,0,0,0.00286157638685111,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN25","HN16",0 "HALLMARK_MTORC1_SIGNALING6",0.0617293402259869,0.0476355014509166,0.0727015781028329,5.27030665151364,3.67986767010701,11.5814764535339,2.98259520289231e-06,4.06873493840804e-06,0.00265543407775459,0.00038509667005247,8.80114291361969e-05,-5.67640138573128e-05,-5.67640138573128e-05,8.79049671786525e-06,4.58430181855984e-06,1.36196026012669e-07,0.000233355015945902,0,0,0.00238514201435229,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN25","HN16",2.74257751011814e-07 "HALLMARK_UV_RESPONSE_UP6",0.0600502046091224,0.0412643940728578,0.0689670521927908,8.23673734676326,3.26803351718409,12.7279371853341,2.34947105911841e-06,2.75227852461662e-06,0.00225870528926087,0.000408724577949809,5.3258892739376e-05,-4.00312538201466e-05,-4.00312538201466e-05,7.34474252710606e-06,4.63725582157854e-06,2.22044604925031e-16,0.00108297539685731,0,0,0.00225412925906204,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN25","HN16",9.39296602128909e-16 "HALLMARK_ANGIOGENESIS6",0.0790893367035214,0.0582638689278528,0.0945241932523833,6.59502877090255,4.33651528711534,10.8469026232873,2.40311210649413e-06,7.46828796600882e-06,0.00314187843057349,0.000809205597831823,5.9717735012078e-05,-0.000110060693260968,-0.000110060693260968,1.25684485395184e-05,1.10751120350705e-05,4.25173229956499e-11,1.4475936360725e-05,0,0,0.00254880331473487,"HALLMARK_ANGIOGENESIS","kendall_tau","HN25","HN16",1.12108457046826e-10 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"HALLMARK_KRAS_SIGNALING_UP6",0.0666536685062148,0.0463152704358734,0.0762488785864546,8.90396023510334,3.61630553263578,12.8388931744426,1.96931514589216e-06,3.14824017999967e-06,0.00226220143353589,0.00047009706403097,3.70282869313031e-05,-3.15258877543658e-05,-3.15258877543658e-05,6.94009863519565e-06,5.33579372132222e-06,0,0.000298837631073967,0,0,0.00229156735044146,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN25","HN16",0 "HALLMARK_HYPOXIA6",0.05385310290652,0.0383701202188002,0.0612192637562418,7.71817977183088,3.40839959809634,11.8253625938164,1.70302487691533e-06,2.221174379618e-06,0.00198095917588761,0.000300774978147492,3.04254971011737e-05,-6.51746787705323e-06,-6.51746787705323e-06,4.5706936741733e-06,3.63345498701613e-06,1.17683640610267e-14,0.000653451270197003,0,0,0.00203920884200305,"HALLMARK_HYPOXIA","kendall_tau","HN25","HN16",4.27148028881708e-14 "HALLMARK_SPERMATOGENESIS6",0.0740759952748093,0.0516480519022084,0.0839372747710046,9.25902383396224,2.95152841444753,12.4531615746905,2.93079378637857e-06,2.83664405871693e-06,0.00240154905115334,0.00061444038116876,4.61576316098328e-05,-9.70330430964499e-05,-9.70330430964499e-05,1.10627860018601e-05,6.62288897838628e-06,0,0.00316205451399187,0,0,0.00232048248200804,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN25","HN16",0 "HALLMARK_OXIDATIVE_PHOSPHORYLATION6",0.100467515105513,0.062625568139051,0.111553183622591,11.284211718594,2.42273474520789,12.3226749830269,4.68189121288684e-06,6.46427488811382e-06,0.00333858744096971,0.00160620459173305,0.000110519470295242,-8.7494590331404e-05,-8.7494590331404e-05,2.08368837172728e-05,1.5665150228936e-05,0,0.0154041698003482,0,0,0.00408291534227489,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN25","HN16",0 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION6",0.0633505536886542,0.0474499459065953,0.0772818475391462,6.4269212267727,4.66940824169246,11.713156371203,1.79044111685815e-06,4.23054643479154e-06,0.00245377006902637,0.000519153926951205,5.65004985502828e-05,-7.84205710482773e-05,-7.84205710482773e-05,8.80141839213502e-06,6.38655334845416e-06,1.30214283800001e-10,3.02068580237957e-06,0,0,0.00210105888488295,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN25","HN16",3.30738656044927e-10 "HALLMARK_MYC_TARGETS_V26",0.0873711284740008,0.0555108022606297,0.100442198658811,9.73318198813289,2.87843921778715,12.6615726017865,4.51165967401484e-06,6.10330512960847e-06,0.00325806151010433,0.00119239669261857,0.00012945305508931,-0.000177131291124904,-0.000177131291124904,2.05209261484061e-05,1.24928645718666e-05,0,0.00399648286762266,0,0,0.00329404615902818,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN25","HN16",0 "HALLMARK_E2F_TARGETS6",0.0779605614542278,0.0606869887923041,0.0904368319835397,4.43963475167286,2.87225342224985,10.9269998278179,8.01457033206908e-06,7.02347697069406e-06,0.00387789212108371,0.000521340428933084,0.000272878549943949,-0.000101149593781194,-0.000101149593781194,1.87679212654932e-05,7.31254750096237e-06,9.01116789253642e-06,0.00407555993430031,0,0,0.003591358372738,"HALLMARK_E2F_TARGETS","kendall_tau","HN25","HN16",1.51821396011788e-05 "HALLMARK_IL6_JAK_STAT3_SIGNALING6",0.043709061400224,0.0303832080964805,0.0488990408316235,8.27585619878167,3.05762150739278,12.6868257467876,1.14622524148776e-06,1.3465459025822e-06,0.00157885121023799,0.000172680396952386,1.5789591286191e-05,-4.14940724200981e-06,-4.14940724200981e-06,2.78113643264814e-06,2.0300046325727e-06,2.22044604925031e-16,0.00223101171702611,0,0,0.0016074142776004,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN25","HN16",9.39296602128909e-16 "HALLMARK_PROTEIN_SECRETION6",0.080298300740067,0.0515964206290374,0.0916447230120708,9.68386011115399,2.88338836358513,12.2333103304462,3.33698975349588e-06,5.34764436382762e-06,0.00294697032854481,0.000958533474756974,6.82140729288648e-05,-0.000131789929680715,-0.000131789929680715,1.53850139819525e-05,1.06171728937198e-05,0,0.00393422068399074,0,0,0.00286708985909639,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN25","HN16",0 "HALLMARK_UV_RESPONSE_DN6",0.0608241915193997,0.0406298318270149,0.0741026719059092,9.57340392635074,4.09273380789129,12.873835098805,1.82764432923542e-06,2.52202161977081e-06,0.00208558527732774,0.000647335198270815,3.74088924179035e-05,-0.000108565628507088,-0.000108565628507088,1.04261548565888e-05,6.66035093917289e-06,0,4.26317026351875e-05,0,0,0.0019993000124433,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN25","HN16",0 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"HALLMARK_ANDROGEN_RESPONSE8",0.0563807528772179,0.0374515414794577,0.070321070988323,7.34736872870941,5.35088311592536,12.1021718945235,1.62216301510025e-06,4.91528865310397e-06,0.00255684408367116,0.000400544125985511,7.60434371347976e-05,-4.81375071535858e-05,-4.81375071535858e-05,6.68725927582053e-06,7.27666975411774e-06,2.02060590481778e-13,8.75260430799329e-08,0,0,0.00240349296192951,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN25","HN22",6.61903215617191e-13 "HALLMARK_TNFA_SIGNALING_VIA_NFKB8",0.0641557580292891,0.0380961279836012,0.0799912613361553,9.50846178264806,5.41132331003148,13.4501216666045,2.06009559094493e-06,5.35121916971442e-06,0.00272237300175037,0.000587099230413866,5.09668343182173e-05,-5.33950507754198e-05,-5.33950507754198e-05,8.46360796940918e-06,9.60230065636405e-06,0,6.25607032844755e-08,0,0,0.00278065006123629,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN25","HN22",0 "HALLMARK_PEROXISOME8",0.0539081472017112,0.0377547296106296,0.0706907455055635,6.67450006642979,5.78488960307556,11.9260713143083,1.96603510242372e-06,3.7911824798885e-06,0.00239942025962777,0.000441612822773991,7.98369260177623e-05,-7.98601384709779e-05,-7.98601384709779e-05,8.31643645126798e-06,7.52688719841883e-06,2.48077114406442e-11,7.25599669237909e-09,0,0,0.00216129810585507,"HALLMARK_PEROXISOME","kendall_tau","HN25","HN22",6.73761400789782e-11 "HALLMARK_INTERFERON_ALPHA_RESPONSE8",0.0754280213897922,0.0372582289083985,0.0872649349642437,14.7506855424777,3.24176042304347,14.7322043515252,2.20084483726825e-06,4.39515120262435e-06,0.00256826712783009,0.00105818898040011,2.90536216793228e-05,-9.68378717064412e-05,-9.68378717064412e-05,1.32326083456659e-05,1.14218184640604e-05,0,0.00118793841552156,0,0,0.00361395954488426,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN25","HN22",0 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"HALLMARK_KRAS_SIGNALING_UP8",0.0666536685062148,0.0422857685942802,0.0804922131583975,8.79877920228188,5.06527473220778,12.8578684993125,1.96931514589216e-06,5.6006142329224e-06,0.00275135046455637,0.000507661471321621,5.47551711420017e-05,-3.83941443273562e-05,-3.83941443273562e-05,7.36405493769717e-06,8.7294833086753e-06,0,4.07811773683875e-07,0,0,0.00273307222490381,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN25","HN22",0 "HALLMARK_HYPOXIA8",0.05385310290652,0.0358656907955244,0.0674704624968566,7.03535151956931,5.83771568423502,11.5184208938969,1.70302487691533e-06,4.73378368601892e-06,0.00253708662897707,0.000356106997812716,7.07211583943768e-05,-1.29454203212959e-05,-1.29454203212959e-05,5.3412656920098e-06,7.42869020724109e-06,1.98752125868396e-12,5.29213628475134e-09,0,0,0.00236013887581553,"HALLMARK_HYPOXIA","kendall_tau","HN25","HN22",5.90233585912205e-12 "HALLMARK_SPERMATOGENESIS8",0.0740759952748093,0.0484391956441972,0.091194983313614,8.7138892811962,4.53902441754207,12.1780540120711,2.93079378637857e-06,5.62493307005152e-06,0.00292501741130375,0.000810831753352035,0.000100094557513856,-0.000144096898733178,-0.000144096898733178,1.4124307717944e-05,1.22263368405485e-05,0,5.65150921660873e-06,0,0,0.00289432916487003,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN25","HN22",0 "HALLMARK_OXIDATIVE_PHOSPHORYLATION8",0.100467515105513,0.0562728269757935,0.118378179087785,12.854427391013,3.79085071788218,13.7320722976058,4.68189121288684e-06,7.03857691010271e-06,0.00342351692313468,0.00179212933291096,9.53557438634206e-05,-0.000112746573678192,-0.000112746573678192,2.2222868847712e-05,2.03543599498181e-05,0,0.00015013217361437,0,0,0.00461824198073927,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN25","HN22",0 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"HALLMARK_PROTEIN_SECRETION8",0.080298300740067,0.0456307143731712,0.0998553781292564,11.5516333138574,4.48561436214632,13.5229025971015,3.33698975349588e-06,5.56960087161897e-06,0.00298439116489693,0.00121208747044156,0.000153462504433724,-0.000175445841479641,-0.000175445841479641,1.89092088128822e-05,1.59788097127011e-05,0,7.27041369441572e-06,0,0,0.0035888589720039,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN25","HN22",0 "HALLMARK_UV_RESPONSE_DN8",0.0608241915193997,0.0352100956537646,0.0784850027058104,9.92588034764246,5.14454579256343,13.4605535408712,1.82764432923542e-06,4.73152395225638e-06,0.00256108732406605,0.000752510744551994,5.53789694331223e-05,-0.000126501699567745,-0.000126501699567745,1.16849357816355e-05,1.02358559470506e-05,0,2.68168836026206e-07,0,0,0.00273363747321694,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN25","HN22",0 "HALLMARK_APOPTOSIS8",0.063332961006391,0.0385908379564059,0.0797610510784457,8.99646914323375,5.16865404447173,12.4778352065601,1.95740989523637e-06,5.50621069516156e-06,0.00273196277251319,0.000640083897461139,8.41129149952166e-05,-8.58031884740469e-05,-8.58031884740469e-05,1.00022758253054e-05,1.07864865174126e-05,0,2.35785898583529e-07,0,0,0.00273385323371893,"HALLMARK_APOPTOSIS","kendall_tau","HN25","HN22",0 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY8",0.0528087342495026,0.0325616252866878,0.0659580095310108,9.01794569768465,5.03439189093556,12.6730013168882,1.66023769677849e-06,3.28069394881796e-06,0.00222282065079404,0.000413274398368214,6.60079244251032e-05,-4.76672599776275e-05,-4.76672599776275e-05,6.72196672149516e-06,6.8444833091177e-06,0,4.79368113870393e-07,0,0,0.00226798925472724,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN25","HN22",0 "HALLMARK_COMPLEMENT8",0.052771750381255,0.030843049723423,0.0646562376316972,10.5984046790859,4.781862235143,13.1874870769141,1.05793118689147e-06,3.12306461555391e-06,0.00204474834697216,0.000436699308669825,3.56330288745887e-05,-4.89276744079291e-05,-4.89276744079291e-05,6.07684606329172e-06,6.4742791680028e-06,0,1.73678694204149e-06,0,0,0.00226641239682359,"HALLMARK_COMPLEMENT","kendall_tau","HN25","HN22",0 "HALLMARK_APICAL_JUNCTION8",0.0567694944253306,0.0344037449746954,0.0727015234204385,9.26291236656545,5.55725369675743,13.0340424821428,1.62171696671117e-06,4.10832660081842e-06,0.00239375094099816,0.000517286771348762,4.8996323374715e-05,-7.45459489565224e-05,-7.45459489565224e-05,8.11905202415624e-06,8.53353990074353e-06,0,2.74052298632199e-08,0,0,0.00236510159946956,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN25","HN22",0 "HALLMARK_GLYCOLYSIS8",0.0652324037652092,0.0467165364182854,0.0831250711876404,5.62083883078064,5.80045834605306,10.16757618234,3.02290969217626e-06,7.72849239191954e-06,0.00327893307099974,0.00050402731728987,0.000167450978933795,-4.10009373300437e-05,-4.10009373300437e-05,9.41536724289267e-06,1.27224653075296e-05,1.90032491964587e-08,6.61339005780803e-09,0,0,0.00279187424149755,"HALLMARK_GLYCOLYSIS","kendall_tau","HN25","HN22",4.10051762477714e-08 "HALLMARK_PI3K_AKT_MTOR_SIGNALING8",0.0597711886736688,0.0346863386814961,0.0731446999006262,11.325781401539,4.37808793393609,13.0738605847923,1.56642752071714e-06,3.23911072966883e-06,0.00219215379259439,0.00068398706899412,5.66542357255733e-05,-6.98130262136625e-05,-6.98130262136625e-05,9.23086557886529e-06,8.55314237497443e-06,0,1.19725047189601e-05,0,0,0.00272818782330963,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN25","HN22",0 "HALLMARK_G2M_CHECKPOINT8",0.0839662119372533,0.0742944461661677,0.120404962855164,1.93162847446336,5.82727780896866,7.93310746264666,1.18234749333712e-05,1.31471028576815e-05,0.00499705691292911,0.00107415570667753,0.000942482878252876,-0.000376610432605019,-0.000376610432605019,3.90016889494567e-05,3.36841738126746e-05,0.0534053787145796,5.6338784748533e-09,2.22044604925031e-15,6.66133814775094e-15,0.00368811894118767,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN25","HN22",0.0671708292709579 "HALLMARK_APICAL_SURFACE8",0.0564786425689986,0.035877267021045,0.0697805675550331,6.76877746823284,5.7537247991317,11.5548928441636,2.44852590171119e-06,6.71490711194871e-06,0.00302711628677524,0.000409186391560505,9.86101685449504e-05,3.63816854876131e-05,3.63816854876131e-05,5.24479210568834e-06,8.50898823249617e-06,1.298761098667e-11,8.72982286459489e-09,0,0,0.00293875766434148,"HALLMARK_APICAL_SURFACE","kendall_tau","HN25","HN22",3.61929633183031e-11 "HALLMARK_XENOBIOTIC_METABOLISM8",0.0610165996631119,0.0422634537163814,0.0799117231082038,6.99852996632072,6.44339907101167,11.9066760619968,1.98166860776298e-06,5.09849952751831e-06,0.00266085853349653,0.000509206905133873,8.74043574100097e-05,-6.64376803511798e-05,-6.64376803511798e-05,8.49942487585741e-06,9.89790391135856e-06,2.58659760277169e-12,1.16826992524466e-10,0,0,0.00239381160985652,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN25","HN22",7.66206242030103e-12 "HALLMARK_WNT_BETA_CATENIN_SIGNALING8",0.0712722312307369,0.0362668424128643,0.0844459370934395,11.3191797574062,3.74485646302264,13.505756234056,2.93616620421422e-06,6.52784107414752e-06,0.00307636267016126,0.000967491029938337,8.23017601712791e-05,-4.78095400278837e-05,-4.78095400278837e-05,1.22750103957912e-05,1.26256348192449e-05,0,0.000180496939013342,0,0,0.00371526588485763,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN25","HN22",0 "HALLMARK_KRAS_SIGNALING_DN8",0.0792131736141425,0.054607160153672,0.0981316611802688,7.92013339140762,5.50616490711266,11.8673069823545,2.57347737459118e-06,6.97852727309232e-06,0.00309063175543181,0.000782495413465076,0.000126055531907318,-7.4803589809277e-05,-7.4803589809277e-05,1.17052285490011e-05,1.33512687063057e-05,2.44249065417534e-15,3.66735017909292e-08,0,0,0.00309808620453564,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN25","HN22",9.47976570729441e-15 "HALLMARK_COAGULATION8",0.0630387859640964,0.0407437596429873,0.0767135494380266,9.40294516724724,4.68379189344749,12.9691343996862,1.68051339902039e-06,3.84145204324344e-06,0.00234988626155902,0.000519774477463647,4.1851923449081e-05,-8.41820112740975e-05,-8.41820112740975e-05,8.42402010457797e-06,7.59225757064254e-06,0,2.81615935771029e-06,0,0,0.00238165904784475,"HALLMARK_COAGULATION","kendall_tau","HN25","HN22",0 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"PEMT8",0.100327446839623,0.0597734070515726,0.128576679880455,9.31638507781884,5.65395152734319,13.0628319075307,4.64445922243364e-06,1.42039774073158e-05,0.00434147862251439,0.00171327197242882,0.000169131857310746,-0.000201414220105684,-0.000201414220105684,2.48637118481063e-05,2.76423673194613e-05,0,1.56800448181116e-08,0,0,0.00444921398007082,"PEMT","kendall_tau","HN25","HN22",0 "EPI_DIFF18",0.0998928914325615,0.0533030921665019,0.117479048607231,9.35629208564165,4.23335698155711,12.5403162203078,6.23431404593445e-06,1.84612582303584e-05,0.00496946398279461,0.00176694136609589,0.000127379552664984,0.000111675237341197,0.000111675237341197,1.71572708782503e-05,2.60895311614666e-05,0,2.30228614921391e-05,0,0,0.00558032175144133,"EPI_DIFF1","kendall_tau","HN25","HN22",0 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"HYPOXIA8",0.0786452905262723,0.0503883995450113,0.0962124398767713,8.13432586305877,4.97502834164168,12.1983438857656,3.50505624469379e-06,8.46211898902023e-06,0.00345936052381275,0.000792055857539416,0.000113097785075972,-6.70703132292809e-05,-6.70703132292809e-05,1.23684213108238e-05,1.40118844625407e-05,4.44089209850063e-16,6.52380942822717e-07,0,0,0.00335272112360375,"HYPOXIA","kendall_tau","HN25","HN22",1.82604514260026e-15 "HALLMARK_PANCREAS_BETA_CELLS9",0.0823560346341179,0.0469384018164506,0.105605377856925,7.21818682935154,11.3378028653221,9.75244002427448,3.02596295134851e-06,2.09499533501288e-05,0.00489652083641817,0.000596079711726634,0.000109579094788235,0.000202407111894091,0.000202407111894091,4.10497651738137e-06,3.60876874160211e-05,5.26911847487099e-13,0,0,0,0.0041788812196004,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN25","HN28",1.6392813032932e-12 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"HALLMARK_ESTROGEN_RESPONSE_EARLY9",0.0627816052544171,0.0298062875352372,0.0837782743349071,9.67684770846791,10.9545445828977,12.7121188724578,2.24865590309669e-06,9.26342798990488e-06,0.00339294619659693,0.000200854525655932,0.000106973446684634,9.32273887795897e-05,9.32273887795897e-05,3.57377160163718e-06,1.79260644803095e-05,0,0,0,0,0.00318893149267462,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN25","HN28",0 "HALLMARK_BILE_ACID_METABOLISM9",0.0597841507040811,0.0274662946919044,0.0800137970801422,10.3018769022414,12.3724025526116,13.065401089827,1.88447593338861e-06,7.85682180237724e-06,0.00312110521062105,0.000184944101170603,6.96521462553498e-05,8.00670297715087e-05,8.00670297715087e-05,2.57342803817277e-06,1.60755353897304e-05,0,0,0,0,0.0028584563598079,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN25","HN28",0 "HALLMARK_MITOTIC_SPINDLE9",0.0896302041009672,0.0398244882951342,0.105058817019206,9.93736287558788,5.12898902523513,13.7697545609918,1.19394710012821e-05,1.30803230487055e-05,0.00500197901334937,0.000370094580724512,0.000126256078131467,0.000295872109847301,0.000295872109847301,8.9487841182031e-06,2.23439864080552e-05,0,2.91302322930065e-07,0,0,0.00605650673158198,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN25","HN28",0 "HALLMARK_INFLAMMATORY_RESPONSE9",0.0513563505526463,0.0292877915074263,0.0800311997822118,5.91324638953414,15.679626534174,10.7337493724586,1.23969253897897e-06,1.25885398267357e-05,0.00371863313136893,9.76746693743388e-05,9.85401349195489e-05,3.77722062504682e-05,3.77722062504682e-05,3.244497362148e-06,2.22489110542837e-05,3.35429839459778e-09,0,0,0,0.00275150272315534,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN25","HN28",7.57131461045487e-09 "HALLMARK_ESTROGEN_RESPONSE_LATE9",0.0689556637412176,0.0337243534746905,0.0953709482980977,9.58088726168037,11.7601841461836,13.0888984709815,3.3750686159613e-06,1.00470932534805e-05,0.0036636268736652,0.000264890985034016,0.000145929069195515,0.000132856532789659,0.000132856532789659,4.94524595143446e-06,2.20825764522887e-05,0,0,0,0,0.00386801211338572,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN25","HN28",0 "HALLMARK_ADIPOGENESIS9",0.0553894195645162,0.0239024390243902,0.0739440171352907,10.1823908633037,12.0233192713264,13.3343918825136,1.30661850444153e-06,8.15568455239219e-06,0.00307608567124417,0.000151857015038375,5.38348940381048e-05,4.92920853508855e-05,4.92920853508855e-05,2.28152047388715e-06,1.39836610855867e-05,0,0,0,0,0.00237969418327491,"HALLMARK_ADIPOGENESIS","kendall_tau","HN25","HN28",0 "HALLMARK_P53_PATHWAY9",0.0705628354994589,0.0312095845079054,0.101711990970506,9.59165709220754,14.619694404246,13.3599802703398,2.64103915691134e-06,1.40924422171878e-05,0.00409065781679415,0.00029391179450868,0.000110603904933315,0.000103598212314828,0.000103598212314828,4.43958302591176e-06,2.77481435214953e-05,0,0,0,0,0.00350972788440662,"HALLMARK_P53_PATHWAY","kendall_tau","HN25","HN28",0 "HALLMARK_HEME_METABOLISM9",0.0588376147373609,0.0262893736977571,0.0811947387099312,9.87505634825962,13.4671039660522,13.3286194503283,2.18405733866403e-06,8.57959558686389e-06,0.00328080065312233,0.000186071010566135,6.37825405807287e-05,8.28217766801718e-05,8.28217766801718e-05,2.65602685003661e-06,1.68691164209828e-05,0,0,0,0,0.00298401343300615,"HALLMARK_HEME_METABOLISM","kendall_tau","HN25","HN28",0 "HALLMARK_CHOLESTEROL_HOMEOSTASIS9",0.0614800746083769,0.0266793689780659,0.0926316305883555,10.393970479146,12.5171607099996,14.1280390524324,2.20697123746182e-06,8.90322310898626e-06,0.00333319581579722,0.000216155724679635,0.000172477437783692,6.47613198934199e-05,6.47613198934199e-05,6.09366670749438e-06,2.16919258353723e-05,0,0,0,0,0.00336783175626961,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN25","HN28",0 "HALLMARK_NOTCH_SIGNALING9",0.0476969159176227,0.0241787962234461,0.0616374387895299,6.76305958990923,10.224907414716,10.829797525475,1.95316249307428e-06,1.00394118103095e-05,0.00346302964229067,0.000190267438439117,3.57019174474478e-05,8.32481221628161e-05,8.32481221628161e-05,1.75882865238625e-06,1.18636416585766e-05,1.35107480758734e-11,0,0,0,0.00290027241573478,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN25","HN28",3.75617960690948e-11 "HALLMARK_ALLOGRAFT_REJECTION9",0.0451671079718023,0.023572820941242,0.0580402995516133,8.04810749081143,12.4442186875123,11.0585765143165,1.26320306650619e-06,5.83609580121254e-06,0.00266445095051846,9.51351609360953e-05,2.16515460414748e-05,5.12925811301172e-05,5.12925811301172e-05,9.7013161812583e-07,9.61450274116445e-06,8.88178419700125e-16,0,0,0,0.00220633662067629,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN25","HN28",3.5527136788005e-15 "HALLMARK_INTERFERON_GAMMA_RESPONSE9",0.0554741861517145,0.0241889664686802,0.0783695850018202,10.0128924002575,13.6853752296862,13.3982932696234,1.19839414428804e-06,8.46406702391754e-06,0.0031084499623133,0.000197285878539225,7.11457670864108e-05,5.7186765305038e-05,5.7186765305038e-05,2.69887181077167e-06,1.62526807459021e-05,0,0,0,0,0.00255567277258414,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN25","HN28",0 "HALLMARK_ANDROGEN_RESPONSE9",0.0563807528772179,0.0239950726779995,0.0780995613212577,10.9501729065807,11.2888777754041,14.2182500046528,1.62216301510025e-06,7.0249369991801e-06,0.00294059518027905,0.000183980235684997,8.90890709869911e-05,5.24816455719562e-05,5.24816455719562e-05,3.60143773325476e-06,1.43801913481855e-05,0,0,0,0,0.00270275373748201,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN25","HN28",0 "HALLMARK_TNFA_SIGNALING_VIA_NFKB9",0.0641557580292891,0.0342310332148548,0.100532732830516,6.8708498547537,15.1764952772773,11.8625001861965,2.06009559094493e-06,1.68086850490115e-05,0.00434382097236482,0.000112316599745862,0.000153707155688862,3.35659186120607e-05,3.35659186120607e-05,5.64526646817644e-06,3.11389809661899e-05,6.38200603475525e-12,0,0,0,0.0032821509268091,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN25","HN28",1.8084913486439e-11 "HALLMARK_PEROXISOME9",0.0539081472017112,0.0219372901895781,0.0697448286696783,11.7785239101029,11.7557314136776,14.2705801826646,1.96603510242372e-06,5.30157815211407e-06,0.00269585111876338,0.000250232948879425,4.0982329216282e-05,0.000104460135286536,0.000104460135286536,1.71480118033531e-06,1.11230140436248e-05,0,0,0,0,0.00300567849763661,"HALLMARK_PEROXISOME","kendall_tau","HN25","HN28",0 "HALLMARK_INTERFERON_ALPHA_RESPONSE9",0.0754280213897922,0.0345020673954166,0.106417874635727,9.30849802011574,13.9262122673795,13.2220883544274,2.20084483726825e-06,1.70294466087196e-05,0.00438523562035016,0.000279813085331617,0.000120679488605285,7.97464556179552e-05,7.97464556179552e-05,4.85191313911751e-06,2.94834356801749e-05,0,0,0,0,0.00327257405853716,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN25","HN28",0 "HALLMARK_TGF_BETA_SIGNALING9",0.061045672474625,0.0321453529000699,0.0860548080276635,6.80678202361538,12.2275418850035,10.6811581608591,2.29769434694243e-06,1.5629228657156e-05,0.00423401972174179,9.04894662437398e-05,0.000103252810738068,4.71696682802026e-05,4.71696682802026e-05,4.08330030925426e-06,2.53737682168577e-05,9.98068294677523e-12,0,0,0,0.00292551119821824,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN25","HN28",2.79459122509706e-11 "HALLMARK_FATTY_ACID_METABOLISM9",0.0562917719677744,0.0245431376751887,0.0797021141796049,10.7447145966291,13.9126378195988,13.9806189102193,1.23362848770465e-06,7.39729793394906e-06,0.00293784383888145,0.00013029120196272,7.73074348004469e-05,4.55643039559556e-05,4.55643039559556e-05,2.73136960436914e-06,1.54660923536331e-05,0,0,0,0,0.00242481276611618,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN25","HN28",0 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE9",0.0829681281229929,0.031972172520953,0.0962709582795131,11.2169644838544,8.30469292347836,12.8218692034475,3.68071812420573e-06,1.68883444064149e-05,0.00453531283712828,0.000493618182833418,4.17783818852536e-05,0.000198236708570639,0.000198236708570639,2.46590714189946e-06,2.50479656597193e-05,0,0,0,0,0.00415412488012053,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN25","HN28",0 "HALLMARK_MTORC1_SIGNALING9",0.0617293402259869,0.0270704743228337,0.0807664459904181,10.2959757783647,10.261001074632,13.5586175795723,2.98259520289231e-06,8.24906834099525e-06,0.00335136741403976,0.000224229710770909,6.78614344829763e-05,9.94620675731092e-05,9.94620675731092e-05,3.34209124954978e-06,1.55838466764346e-05,0,0,0,0,0.0033259596970886,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN25","HN28",0 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"HALLMARK_PEROXISOME10",0.0539081472017112,0.0575408956291522,0.0629995792748795,-1.64308847631774,5.15337829025019,2.78238640835845,1.96603510242372e-06,2.82216242884905e-06,0.00218819503958691,6.92593685441079e-05,4.55645601217664e-05,5.04746500765195e-06,5.04746500765195e-06,3.01229352598366e-06,3.74893844166072e-06,0.100364628770797,2.55835141294014e-07,0.00539607510674567,7.67505423882042e-07,0.00184673289609394,"HALLMARK_PEROXISOME","kendall_tau","HN25","HN5",0.121428810117754 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"HALLMARK_HYPOXIA10",0.05385310290652,0.0532235578616738,0.0629329623165952,0.272605503206942,5.61329095126123,4.86138415879664,1.70302487691533e-06,3.53013228631673e-06,0.00228760948661087,0.000122807647844484,4.59930025385868e-05,2.6446511756447e-05,2.6446511756447e-05,2.51651447315316e-06,3.88901162469153e-06,0.785156481171691,1.98514393812133e-08,1.16567787489252e-06,5.95543181436398e-08,0.00204427358542706,"HALLMARK_HYPOXIA","kendall_tau","HN25","HN5",0.812802836142525 "HALLMARK_SPERMATOGENESIS10",0.0740759952748093,0.0783677152669511,0.0848214713965496,-1.35234857940392,5.06493184805468,2.41042948820107,2.93079378637857e-06,7.04050452976945e-06,0.00315773626450152,9.43027890179058e-05,5.87949645549021e-05,3.72297195677922e-06,3.72297195677922e-06,4.400949236383e-06,7.0686311938635e-06,0.176263830618521,4.0854648397648e-07,0.0159337509804427,1.22563945192944e-06,0.00226959189430974,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN25","HN5",0.205641135721608 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"HALLMARK_IL6_JAK_STAT3_SIGNALING10",0.043709061400224,0.0438505148675229,0.0511453224726051,-0.0631646354836296,5.14991563220263,4.66241635387816,1.14622524148776e-06,3.76887024376819e-06,0.00221700146261926,5.96563722827163e-05,5.24550070459236e-05,1.30421646453373e-05,1.30421646453373e-05,1.98501425486996e-06,2.34796710471993e-06,0.949635405318227,2.60603657986636e-07,3.12518123068983e-06,7.81810973959907e-07,0.00182199585383966,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN25","HN5",0.958959272440776 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"HALLMARK_APOPTOSIS10",0.063332961006391,0.0625952675920229,0.0746704677686934,0.273333094886108,5.45423551987339,4.54111279515861,1.95740989523637e-06,5.22654713579274e-06,0.00268029047512189,0.000151240113408576,6.68902088346067e-05,-4.56949537583524e-06,-4.56949537583524e-06,4.22083163091645e-06,6.97072748585048e-06,0.784597177526956,4.9183978445555e-08,5.59580817771632e-06,1.47551935336665e-07,0.00199812203036606,"HALLMARK_APOPTOSIS","kendall_tau","HN25","HN5",0.812802836142525 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY10",0.0528087342495026,0.0563217049057965,0.0626892152242227,-1.55960047539067,5.79524701506993,3.64812570041279,1.66023769677849e-06,3.3134335879525e-06,0.0022301729270913,8.0093764902308e-05,5.38619960977456e-05,8.54524852537258e-06,8.54524852537258e-06,2.80678070421363e-06,2.9464897883418e-06,0.118854324109483,6.82206935387342e-09,0.000264160396657553,2.04662080616203e-08,0.00195347588953483,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN25","HN5",0.14262518893138 "HALLMARK_COMPLEMENT10",0.052771750381255,0.0525110057109235,0.0621781227392018,0.114700197445035,5.84548893103642,4.46187041949649,1.05793118689147e-06,4.00983135030971e-06,0.00225116914895376,9.64030955259926e-05,3.35391280880605e-05,-7.08456731677827e-06,-7.08456731677827e-06,2.48942089561704e-06,4.59418331332968e-06,0.908682757423621,5.05082531354617e-09,8.12473535427571e-06,1.51524759406385e-08,0.00151426584011967,"HALLMARK_COMPLEMENT","kendall_tau","HN25","HN5",0.927844413220931 "HALLMARK_APICAL_JUNCTION10",0.0567694944253306,0.0582602519608445,0.0673576167762403,-0.61735855612315,5.64420670286927,3.55794196241051,1.62171696671117e-06,4.10922989403823e-06,0.00239393961092368,0.000105087995382008,5.86008420529463e-05,-4.64004037948641e-06,-4.64004037948641e-06,3.41910383988912e-06,6.43782817651114e-06,0.536998251616257,1.65944609165081e-08,0.000373771869633943,4.97833827495242e-08,0.00175535364290657,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN25","HN5",0.579366921009833 "HALLMARK_GLYCOLYSIS10",0.0652324037652092,0.0608712876224109,0.0726458770922009,1.64197694143479,3.70285084044027,5.38373468587505,3.02290969217626e-06,3.93150843606003e-06,0.00263712307794617,0.000157992672081455,6.56540735851458e-05,4.26612890117532e-05,4.26612890117532e-05,3.90839971609218e-06,4.68326287622636e-06,0.100594782851673,0.000213190237426497,7.29560172274546e-08,2.18868051682364e-07,0.0024812835985387,"HALLMARK_GLYCOLYSIS","kendall_tau","HN25","HN5",0.121582183590511 "HALLMARK_PI3K_AKT_MTOR_SIGNALING10",0.0597711886736688,0.0595589319469917,0.0675746452255697,0.0899804270053492,4.49264473792542,3.43705034247162,1.56642752071714e-06,3.89808117381495e-06,0.00233762886158861,0.000114650194354285,2.92212471149867e-05,-1.96974179905024e-06,-1.96974179905024e-06,2.91696226534743e-06,5.33891863173641e-06,0.928302768712691,7.03440780802644e-06,0.0005880862875971,2.11032234240793e-05,0.00163481215199456,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN25","HN5",0.942732345428432 "HALLMARK_G2M_CHECKPOINT10",0.0839662119372533,0.0825236312726,0.0959575556553093,0.312555566112662,2.88775845973557,4.31387610137293,1.18234749333712e-05,9.37878791000238e-06,0.00460459149581953,0.000271224287771418,0.000324027478433223,5.16141976790296e-05,5.16141976790296e-05,1.7143045485026e-05,9.59773837593111e-06,0.754618340892555,0.00387997693224751,1.60416871199942e-05,4.81250613599826e-05,0.00445434511417558,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN25","HN5",0.78672975965394 "HALLMARK_APICAL_SURFACE10",0.0564786425689986,0.0562548587066589,0.064596591998199,0.0732371628556101,4.81786564831568,3.14023137934583,2.44852590171119e-06,6.78819779436889e-06,0.00303919787050466,0.000155140435028123,6.91815561375047e-05,6.36410800256867e-05,6.36410800256867e-05,2.73911714947526e-06,6.95649928966479e-06,0.941617394095171,1.45102017645726e-06,0.00168814445096421,4.35306052937179e-06,0.00258243307789203,"HALLMARK_APICAL_SURFACE","kendall_tau","HN25","HN5",0.954762624776282 "HALLMARK_XENOBIOTIC_METABOLISM10",0.0610165996631119,0.0641057617349525,0.0727049342278333,-1.18889318489514,5.98101210662922,3.33341242971889,1.98166860776298e-06,4.66976051773683e-06,0.00257903647230895,0.000115730138240683,6.12676398662202e-05,1.36391252238566e-06,1.36391252238566e-06,3.71905493525239e-06,6.55480325433119e-06,0.234481702283275,2.21755391827116e-09,0.000857876721165773,6.65266175481349e-09,0.00199331034707866,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN25","HN5",0.267676597179255 "HALLMARK_WNT_BETA_CATENIN_SIGNALING10",0.0712722312307369,0.058516939113954,0.0797521829719777,3.65867084204512,3.33776417501231,6.13596200229809,2.93616620421422e-06,9.1182510028429e-06,0.00347194717803384,0.000357785668316203,0.000112782774465119,3.13172201505474e-05,3.13172201505474e-05,6.35469110454446e-06,1.1877031236866e-05,0.000253526710350727,0.000844553956026006,8.46453795944058e-10,2.53936138783217e-09,0.00283188153700662,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN25","HN5",0.000379805619582745 "HALLMARK_KRAS_SIGNALING_DN10",0.0792131736141425,0.0818373358338507,0.0921236741160183,-0.811408881507452,5.83313546444877,3.52885607482773,2.57347737459118e-06,7.78580391739811e-06,0.00321858374009273,0.000176648080309557,7.01775072922215e-05,4.70536630184544e-06,4.70536630184544e-06,4.79871341702863e-06,8.39676708558982e-06,0.417130900419333,5.43953704301714e-09,0.000417360049020044,1.63186111290514e-08,0.0023835922849335,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN25","HN5",0.458026086734954 "HALLMARK_COAGULATION10",0.0630387859640964,0.0676891897901491,0.0742404552476494,-1.60822316740155,5.7214083685219,2.61166328619969,1.68051339902039e-06,6.58107347569357e-06,0.00287429763154652,9.56920922735079e-05,6.31347639788353e-05,-1.32740401201882e-05,-1.32740401201882e-05,3.73318340433331e-06,6.19239571933543e-06,0.107786310945916,1.05644630821189e-08,0.00901029483627624,3.16933892463567e-08,0.00196317171562705,"HALLMARK_COAGULATION","kendall_tau","HN25","HN5",0.129608079419629 "HALLMARK_HEDGEHOG_SIGNALING10",0.0639525881051557,0.0671964851069329,0.0751080606000475,-1.30067820098929,4.93181411644972,3.80224572665212,2.64338849394745e-06,3.4766688608745e-06,0.00247387496749976,9.5268800869016e-05,9.07627347981627e-05,-1.02965484391352e-05,-1.02965484391352e-05,5.01637703291672e-06,4.22957823917494e-06,0.193368626930345,8.14694263606697e-07,0.000143390402094656,2.44408279082009e-06,0.00216965299560866,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN25","HN5",0.223161437949054 "CELL_CYCLE10",0.0604739460591778,0.0620674405749033,0.0699076192983522,-0.605274168099674,5.07691175407494,3.82080773878398,2.4579601916862e-06,4.37305526359356e-06,0.00261362113843605,0.000104003102151294,6.68652735897318e-05,2.94586741358431e-05,2.94586741358431e-05,3.35272849606968e-06,4.11057644238259e-06,0.544996842309359,3.83618929955531e-07,0.000133015317305141,1.15085678986659e-06,0.00232162892536986,"CELL_CYCLE","kendall_tau","HN25","HN5",0.586919676333156 "PEMT10",0.100327446839623,0.105093906043703,0.122352383266841,-1.0900503646894,6.18710314733488,4.1531136081719,4.64445922243364e-06,1.4376013770484e-05,0.00436124672460956,0.000384964930846509,0.000251451088419657,-4.36150764869716e-05,-4.36150764869716e-05,1.25722757420882e-05,1.71686077469043e-05,0.275690958950134,6.12798700672101e-10,3.27981801742094e-05,1.8383961020163e-09,0.00342458927133082,"PEMT","kendall_tau","HN25","HN5",0.311742853582074 "EPI_DIFF110",0.0998928914325615,0.0925990798989442,0.117180099052454,1.48573635095625,5.52615071759401,4.80718679323372,6.23431404593445e-06,1.77661595076965e-05,0.00489902781719301,0.000697624259204895,0.000204733180709314,0.000161141905304986,0.000161141905304986,9.68597822058803e-06,2.60467536262944e-05,0.137348871553125,3.27332960736726e-08,1.53068959574121e-06,9.81998882210178e-08,0.00424332633881438,"EPI_DIFF1","kendall_tau","HN25","HN5",0.163318779521208 "EPI_DIFF210",0.0956115639619175,0.0922882374171384,0.107887214762911,0.868247353822104,3.98377195314699,4.16795302891305,5.90273515618293e-06,8.64798915638878e-06,0.00381454116671609,0.000354441050509847,0.000111117587447203,2.71744172351575e-05,2.71744172351575e-05,9.39511244322489e-06,1.39070481866039e-05,0.385258935931559,6.78299668577242e-05,3.07347246291112e-05,9.22041738873336e-05,0.00314728143282988,"EPI_DIFF2","kendall_tau","HN25","HN5",0.42541268418358 "STRESS10",0.0913189203480579,0.0876117851916326,0.107438141447474,0.951329084454469,5.0543188315119,4.27649607486994,3.52109869916122e-06,1.15639186087062e-05,0.00388394352531901,0.000357491431390907,0.000168066385685358,-4.6015001115127e-05,-4.6015001115127e-05,1.007098084261e-05,2.13936244240884e-05,0.341437347098504,4.31929538358133e-07,1.89857902808122e-05,1.2957886150744e-06,0.0024784860874924,"STRESS","kendall_tau","HN25","HN5",0.379518261047108 "HYPOXIA10",0.0786452905262723,0.0791745998181354,0.0907413958920817,-0.150194620078804,4.92689669133098,4.10399503768342,3.50505624469379e-06,8.81462022237343e-06,0.00350993966715487,0.000180772425049758,0.000154108683144917,4.10923314037859e-05,4.10923314037859e-05,5.92759703368222e-06,7.84351104713047e-06,0.880611070304779,8.35458983328152e-07,4.06076176147074e-05,2.50637694998446e-06,0.00301913359118725,"HYPOXIA","kendall_tau","HN25","HN5",0.902089389092701 "HALLMARK_PANCREAS_BETA_CELLS11",0.0666050356191201,0.0582487986743306,0.0955722047271343,2.75719861500213,9.73955341907768,13.9866028356169,6.72167220847496e-06,2.36345951447541e-06,0.00301415522542393,0.000249116633993629,0.000203307903683796,3.72875097929947e-05,3.72875097929947e-05,8.74573697384816e-06,7.02095192379118e-06,0.0058298928438496,0,0,0,0.00396682156304575,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN16","HN17",0.00786233255087974 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"HALLMARK_ESTROGEN_RESPONSE_EARLY11",0.0438919749653701,0.0416806622224135,0.0773438993945399,1.07461377577949,15.4141757532574,15.9455232857323,2.54358086016867e-06,1.59085471790633e-06,0.00203333115307738,0.000128172322652527,0.000154995019401248,3.70471063942512e-06,3.70471063942512e-06,4.60979062580168e-06,4.90223362682907e-06,0.282547681663516,0,0,0,0.00321993075307688,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN16","HN17",0.31888298813464 "HALLMARK_BILE_ACID_METABOLISM11",0.0458022264863311,0.0500296841862191,0.0727495089290864,-1.91915127379456,13.9637999276453,13.7192093670149,3.51740645064396e-06,1.23480953462695e-06,0.00217995779437835,7.97299112901368e-05,8.56931474167598e-05,2.26477100179041e-05,2.26477100179041e-05,3.62411182702901e-06,2.64253252147585e-06,0.0549651920481187,0,0,0,0.00257666431649442,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN16","HN17",0.0689851289739462 "HALLMARK_MITOTIC_SPINDLE11",0.0712586271397228,0.0844883216857984,0.101578363434758,-3.77892754762897,11.5105196142663,7.44831656428151,9.62053501993632e-06,2.53585304958983e-06,0.00348660122031846,0.000201467250148126,0.00034520568722498,0.000118317123584353,0.000118317123584353,6.83842632213474e-06,5.16465594231393e-06,0.000157505239166689,0,9.45910016980633e-14,0,0.00360520572465297,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN16","HN17",0.000239930260699515 "HALLMARK_INFLAMMATORY_RESPONSE11",0.0377023217422396,0.032999325922355,0.0618807878595935,2.57238025745142,14.2662304952809,15.3015120488229,2.3397521512775e-06,9.02805063827062e-07,0.00180071019742338,0.000126584389315535,7.70524546046874e-05,2.81117786949353e-05,2.81117786949353e-05,2.77236098071603e-06,3.46262120405274e-06,0.010100188829838,0,0,0,0.00267326471293422,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN16","HN17",0.0133608797119117 "HALLMARK_ESTROGEN_RESPONSE_LATE11",0.0496023578657877,0.0483822696424001,0.0799835005158099,0.578563899311569,13.6951601892834,14.5709238387885,2.951635883009e-06,1.39549393727145e-06,0.00208497717500227,0.000143744642011624,0.000161293544359745,1.14264397889849e-05,1.14264397889849e-05,4.8212335352462e-06,4.60363725196695e-06,0.562883469603993,0,0,0,0.00302549474956621,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN16","HN17",0.602321164926565 "HALLMARK_ADIPOGENESIS11",0.0366311316354432,0.0399082285013679,0.0595715540886567,-1.84572510178898,13.4447145098361,11.8463516987834,2.12561079217967e-06,9.26812444100388e-07,0.00174711855244001,7.56142925871762e-05,0.000103827237828863,1.23157262858541e-05,1.23157262858541e-05,2.81138508762525e-06,2.65514650076079e-06,0.0649321305343054,0,0,0,0.00217454999372217,"HALLMARK_ADIPOGENESIS","kendall_tau","HN16","HN17",0.0808900270215499 "HALLMARK_P53_PATHWAY11",0.0493229325702962,0.0504327851840949,0.0863091031341084,-0.437405802444931,12.4725324351731,13.5755249066599,4.51084387945722e-06,1.82731275605754e-06,0.00251756958901135,0.000216108857612435,0.000286761601837902,-4.79339519415638e-06,-4.79339519415638e-06,8.69365559089046e-06,6.8839716336928e-06,0.66181707680483,0,0,0,0.00341747152051875,"HALLMARK_P53_PATHWAY","kendall_tau","HN16","HN17",0.696151057533524 "HALLMARK_HEME_METABOLISM11",0.0419389300627888,0.0374555938021136,0.0653133604428459,2.26888460442931,12.3522265780758,15.714353575814,2.66807994821904e-06,1.13653138011851e-06,0.0019505412911132,0.000102082776335837,6.69737066770985e-05,1.46956024409612e-05,1.46956024409612e-05,3.48089489242866e-06,3.04267557989534e-06,0.0232753441973301,0,0,0,0.00277828541931016,"HALLMARK_HEME_METABOLISM","kendall_tau","HN16","HN17",0.0301451594450003 "HALLMARK_CHOLESTEROL_HOMEOSTASIS11",0.0406353709074141,0.0432496542085583,0.084305033639396,-1.1083893753113,15.7415214879095,16.2133239907436,3.57192046936416e-06,1.89122721726703e-06,0.00233733773482379,0.000160058112518943,0.000232528116265152,-1.8906067959225e-05,-1.8906067959225e-05,7.59602132690809e-06,6.31203697165266e-06,0.267693691428426,0,0,0,0.00351411604687839,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN16","HN17",0.303575488061552 "HALLMARK_NOTCH_SIGNALING11",0.03798435775946,0.0318445510106457,0.0583493384549723,3.10966263115712,12.4004337420603,14.6433253503191,2.58698557733443e-06,1.21138260932817e-06,0.00194894027272839,0.000100696103748436,6.59509474895395e-05,2.85421647011133e-05,2.85421647011133e-05,2.59708263679971e-06,3.17619111300512e-06,0.00187301141613316,0,0,0,0.00276867487327636,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN16","HN17",0.00262534138900191 "HALLMARK_ALLOGRAFT_REJECTION11",0.0388726791268356,0.035556316312462,0.0591441935326294,1.81732174746538,13.0216425590925,14.1288290189815,2.49939148057949e-06,7.30732681513445e-07,0.00179725461804747,9.77731573854551e-05,6.92671571748509e-05,3.12913120299519e-05,3.12913120299519e-05,2.32348786201689e-06,2.68718231704573e-06,0.0691678618958924,0,0,0,0.00230577436109665,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN16","HN17",0.0858031704531324 "HALLMARK_INTERFERON_GAMMA_RESPONSE11",0.0332405920844584,0.0324665004454995,0.0557676533635265,0.466774213896138,13.1179136760728,14.862997412834,1.81942981706913e-06,8.30813010936255e-07,0.00162795664193043,6.70104680732422e-05,7.57647790470841e-05,2.55239797761903e-06,2.55239797761903e-06,2.8490323969264e-06,2.35777439612233e-06,0.640661426500733,0,0,0,0.00225999532502069,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN16","HN17",0.675711065080594 "HALLMARK_ANDROGEN_RESPONSE11",0.0409881511289962,0.0410608749370838,0.0706671020921981,-0.0393333236417449,15.0286338706137,14.6551150031387,2.02634532091842e-06,1.29212593886654e-06,0.00182166716493024,0.000105232457252708,0.000145482247978744,2.65196502117039e-06,2.65196502117039e-06,3.79994142300718e-06,3.98119806680938e-06,0.968624638740728,0,0,0,0.00278563633554574,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN16","HN17",0.974424786278098 "HALLMARK_TNFA_SIGNALING_VIA_NFKB11",0.0432197203320425,0.0389103836396684,0.0817881222158595,1.85757079799653,14.6341838090253,16.7797408364306,3.18249682313687e-06,2.09933477549648e-06,0.00229822357455347,0.000195340125229946,0.000144838883020471,-8.39916007811317e-06,-8.39916007811317e-06,6.84586401577217e-06,6.42970026902739e-06,0.0632299886436867,0,0,0,0.00386210033455627,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN16","HN17",0.07885309294271 "HALLMARK_PEROXISOME11",0.040062802093352,0.0490163780672548,0.0713124073807305,-4.45655911976301,14.5137255395421,12.5505891851127,2.81165981892086e-06,1.12473557455698e-06,0.0019840351290937,7.83631767618037e-05,0.000156526859178462,-2.59469090769593e-06,-2.59469090769593e-06,4.53587011901581e-06,3.05592609953806e-06,8.32856402621651e-06,0,0,0,0.00236013345677437,"HALLMARK_PEROXISOME","kendall_tau","HN16","HN17",1.41333207717614e-05 "HALLMARK_INTERFERON_ALPHA_RESPONSE11",0.0422965153078158,0.0408069614541672,0.0710192102470274,0.670511780613411,12.65199236144,14.7239632733191,3.38354443073285e-06,1.45159689110995e-06,0.00219889547769848,0.000127192375069488,0.000106715330862703,7.89000221681439e-06,7.89000221681439e-06,5.05385895646858e-06,4.11033501397303e-06,0.502531599155878,0,0,0,0.00299335235724033,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN16","HN17",0.545685282185885 "HALLMARK_TGF_BETA_SIGNALING11",0.0372656624583279,0.0400391803308972,0.0747473554453801,-1.28178466763696,15.7113487861132,15.3249850938278,2.90570695637353e-06,1.67629717856474e-06,0.00214056164006979,9.81669518245205e-05,0.000239980311937882,-1.02195018699337e-05,-1.02195018699337e-05,5.5912997313626e-06,5.02936304272038e-06,0.199918194163617,0,0,0,0.00308748841572676,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN16","HN17",0.230042853558135 "HALLMARK_FATTY_ACID_METABOLISM11",0.0348902736746205,0.0367795138446028,0.0621448303108692,-1.05179150200705,14.5262198419999,14.0156873392603,2.03476470509329e-06,1.09161165722507e-06,0.00176815620416251,8.20928307615947e-05,0.000106357058631568,1.65163466832969e-06,1.65163466832969e-06,3.42024603466958e-06,3.1753051548845e-06,0.292895218765499,0,0,0,0.00245391852879671,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN16","HN17",0.32929711019907 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE11",0.0551920273248241,0.0588164433529175,0.0796390168749324,-1.44740492090605,11.8192499079455,10.8066139681923,4.51645866706696e-06,1.65395214475087e-06,0.00248403116160362,0.00010619413906978,0.000133539731875245,3.97337210598248e-05,3.97337210598248e-05,4.17829712448057e-06,3.61269721695179e-06,0.147783548340119,0,0,0,0.00282043891920549,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN16","HN17",0.173967420268249 "HALLMARK_MTORC1_SIGNALING11",0.0476355014509166,0.0507147656862187,0.0775202538514167,-1.29896744804747,12.6694591856179,11.8231908975485,4.06873493840804e-06,1.45076123677155e-06,0.00234936080140527,0.000166647503509381,0.000191686787392515,2.72072451734354e-05,2.72072451734354e-05,5.4639493828822e-06,5.04017657297435e-06,0.193955100682253,0,0,0,0.00286901406987918,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN16","HN17",0.223618821963068 "HALLMARK_UV_RESPONSE_UP11",0.0412643940728578,0.0404658449935616,0.0644620482157139,0.407863162832084,12.188827188881,12.8778499946345,2.75227852461662e-06,9.81034291598975e-07,0.00193217825684267,0.000122771972614665,0.000112008533149463,2.30527915498222e-05,2.30527915498222e-05,3.52213221521354e-06,3.37214887905899e-06,0.683374138577422,0,0,0,0.00252027632516973,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN16","HN17",0.716263803000934 "HALLMARK_ANGIOGENESIS11",0.0582638689278528,0.0451974221883036,0.0879886389041318,4.18197367911768,11.4241690943976,13.833751278241,7.46828796600882e-06,2.19401799862818e-06,0.00310842499742828,0.00040158870688923,0.000153396496831023,0.000122817911801535,0.000122817911801535,6.66998583073021e-06,9.46818016726644e-06,2.88989431735942e-05,0,0,0,0.00427286005450727,"HALLMARK_ANGIOGENESIS","kendall_tau","HN16","HN17",4.66829082034983e-05 "HALLMARK_MYC_TARGETS_V111",0.0690738818985687,0.0651825751978353,0.0861117745723231,1.04213228284672,8.22052125375825,8.49638842147414,1.04854037845168e-05,3.35724298020572e-06,0.00372057075792445,0.000245997960803803,0.000113247533213083,0.000179233235064584,0.000179233235064584,4.19569109301585e-06,5.96787343300154e-06,0.297350353178099,2.22044604925031e-16,0,0,0.00412241194184828,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN16","HN17",0.333986643111217 "HALLMARK_DNA_REPAIR11",0.0546771694659019,0.0613165445128695,0.0812726583773319,-2.41566833266455,11.9880856404816,9.39817846871556,5.63192774094414e-06,1.82212115411833e-06,0.00273021041223245,0.000134575162498659,0.000182438899123729,5.78381040162073e-05,5.78381040162073e-05,4.82171298042125e-06,4.40883736749223e-06,0.0157063606925141,0,0,0,0.00291339483124576,"HALLMARK_DNA_REPAIR","kendall_tau","HN16","HN17",0.0205458066456024 "HALLMARK_KRAS_SIGNALING_UP11",0.0463152704358734,0.0396944937481275,0.0729945138202816,3.22095846274172,14.4920690696149,16.467242572821,3.14824017999967e-06,9.76963322821711e-07,0.00203105969947252,0.000147850503366671,0.000116202698078961,4.07124052556758e-05,4.07124052556758e-05,3.28911438986376e-06,3.98928354182803e-06,0.0012776266373149,0,0,0,0.00299375821964047,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN16","HN17",0.0018167943476207 "HALLMARK_HYPOXIA11",0.0383701202188002,0.0358540464133322,0.0657147656764403,1.37586647665727,13.0255012700121,15.6760036010719,2.221174379618e-06,1.02304049770272e-06,0.00180117041873353,0.000114044203794132,0.000100399609848549,-3.11435065173619e-06,-3.11435065173619e-06,4.30712838779566e-06,3.52852249490932e-06,0.168862975676536,0,0,0,0.00271508563339304,"HALLMARK_HYPOXIA","kendall_tau","HN16","HN17",0.197594884970752 "HALLMARK_SPERMATOGENESIS11",0.0516480519022084,0.0565625181461193,0.0753242012609221,-2.46348697291963,13.9972085492702,11.3275500262553,2.83664405871693e-06,1.04307278016937e-06,0.00196969968241006,8.05739886924547e-05,0.000133932093226024,2.86875979658542e-05,2.86875979658542e-05,2.76114109553427e-06,2.64328933562545e-06,0.0137592895389234,0,0,0,0.00232817693985863,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN16","HN17",0.0180590675198369 "HALLMARK_OXIDATIVE_PHOSPHORYLATION11",0.062625568139051,0.0616551594818169,0.0884798772376868,0.307603612677878,11.0681857101357,10.0501386704539,6.46427488811382e-06,3.38809391211939e-06,0.00313884832386549,0.000200206650853888,0.000137861092674789,7.71301816556384e-05,7.71301816556384e-05,5.35648541206817e-06,7.02403778010127e-06,0.758383970900328,0,0,0,0.0039056233654966,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN16","HN17",0.789955314241617 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"HALLMARK_E2F_TARGETS11",0.0606869887923041,0.0731041149555384,0.0860025174047269,-4.1141270185514,12.0601939034863,6.76894744725372,7.02347697069406e-06,1.98586058893158e-06,0.00300155585648937,0.000148274877278219,0.000202533785022315,9.61940296789815e-05,9.61940296789815e-05,4.30621231265484e-06,3.53102770156111e-06,3.8864740179223e-05,0,1.29722899089302e-11,0,0.00316553895902574,"HALLMARK_E2F_TARGETS","kendall_tau","HN16","HN17",6.20148364325187e-05 "HALLMARK_IL6_JAK_STAT3_SIGNALING11",0.0303832080964805,0.0267726981832324,0.0436774364606796,2.53959514257994,11.5483112647341,13.1222569126119,1.3465459025822e-06,5.74648598622642e-07,0.00138607160753146,5.71283598474696e-05,3.96883882321584e-05,1.85703071412635e-05,1.85703071412635e-05,1.22522404546228e-06,1.55958625803842e-06,0.0110980855058191,0,0,0,0.00191100955033589,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN16","HN17",0.0146151719539119 "HALLMARK_PROTEIN_SECRETION11",0.0515964206290374,0.051950392987627,0.0842105216359293,-0.126954057383179,12.3364761015275,13.0926922031331,5.34764436382762e-06,2.3263734023969e-06,0.00277020175550889,0.000174591939560525,0.000161611483471371,2.49777935736753e-05,2.49777935736753e-05,6.88921789623006e-06,5.97119627871958e-06,0.898976761129636,0,0,0,0.00352646345190832,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN16","HN17",0.919301453120393 "HALLMARK_UV_RESPONSE_DN11",0.0406298318270149,0.0352653140612522,0.0664665819195269,2.7259212938234,13.2268311180131,15.4877246459232,2.52202161977081e-06,1.25086471785348e-06,0.00194239191143916,0.000123494847050614,9.38646052065246e-05,1.47362689233532e-05,1.47362689233532e-05,3.71561152662269e-06,3.95853453822883e-06,0.00641222866001478,0,0,0,0.00294126739818064,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN16","HN17",0.00860819737919793 "HALLMARK_APOPTOSIS11",0.0417382243773198,0.0428782436782635,0.075337109945576,-0.564958042436294,15.3726296124516,15.3930203559874,2.60768344461307e-06,1.36416886710757e-06,0.00199295065461256,0.000125428864400262,0.000141365075023428,2.23093065871089e-06,2.23093065871089e-06,4.67697994948936e-06,4.34650726053856e-06,0.572102303041451,0,0,0,0.00296200521219489,"HALLMARK_APOPTOSIS","kendall_tau","HN16","HN17",0.61107384957016 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY11",0.0357281524484558,0.0305115351644373,0.0553605066047901,3.13593750031811,11.1703730482634,15.7451899638378,1.90591897197266e-06,7.612976317555e-07,0.001633161536324,8.68434707839883e-05,5.50759763652772e-05,5.44967286592426e-06,5.44967286592426e-06,2.98893952244772e-06,2.39069772706824e-06,0.00171305706527836,0,0,0,0.00239910266286304,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN16","HN17",0.00240975491479348 "HALLMARK_COMPLEMENT11",0.0341583323623498,0.0320263006590265,0.0588117018192394,1.32417886159223,15.2256852317292,16.0450214591745,1.64919394511451e-06,8.43158315793043e-07,0.00157871855025129,8.30479001015147e-05,6.93033542023408e-05,9.00097139009499e-06,9.00097139009499e-06,2.52179586346451e-06,2.68686355193406e-06,0.185443649448055,0,0,0,0.00244037692411047,"HALLMARK_COMPLEMENT","kendall_tau","HN16","HN17",0.214680660975333 "HALLMARK_APICAL_JUNCTION11",0.038766205271832,0.0342925301648706,0.0621281889601657,2.53998177431881,14.2957116917438,16.6716293169473,1.95465209739998e-06,1.04753281516999e-06,0.00173268142270008,7.64301803907221e-05,5.93923793777715e-05,1.13691662271087e-05,1.13691662271087e-05,2.57059401139813e-06,2.68770566588933e-06,0.0110858245653824,0,0,0,0.00265256041191495,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN16","HN17",0.0146151719539119 "HALLMARK_GLYCOLYSIS11",0.0481756791191288,0.0496185977975972,0.0768711604687258,-0.658515171108114,12.090247853398,13.3379652446084,3.60136449004008e-06,1.09986141890955e-06,0.00216823105524979,0.000152622953271081,0.000173335481516451,1.31886721559935e-05,1.31886721559935e-05,5.53321880165823e-06,4.07479861996533e-06,0.510207151730368,0,0,0,0.00276132774546185,"HALLMARK_GLYCOLYSIS","kendall_tau","HN16","HN17",0.55299871929485 "HALLMARK_PI3K_AKT_MTOR_SIGNALING11",0.0361791997405679,0.0374506024202073,0.056769056452155,-0.726535596423562,12.23695727278,11.8201441585851,2.06073476183068e-06,9.01598491064113e-07,0.00172114300768262,7.36417457503366e-05,9.60813539737913e-05,1.16789390196513e-05,1.16789390196513e-05,2.73112967108422e-06,2.57115562451008e-06,0.467510493764167,0,0,0,0.00215922259707977,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN16","HN17",0.510484995976472 "HALLMARK_G2M_CHECKPOINT11",0.0699030363083021,0.0842458798552031,0.0949216848218901,-4.08613248193248,10.732309299222,4.92653699115631,9.48428215342853e-06,2.73670870944759e-06,0.0034958533812041,0.000201626103824383,0.000275077566159689,0.00013886505414222,0.00013886505414222,5.3342714829912e-06,4.59588839021944e-06,4.38623388505643e-05,0,8.3699772579493e-07,0,0.00371032378998926,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN16","HN17",6.96114851393572e-05 "HALLMARK_APICAL_SURFACE11",0.0390069805726537,0.0395299181498633,0.0654688654703543,-0.277547131250488,12.4298418119458,13.9514127557416,2.65497302377326e-06,7.95009502097892e-07,0.00185741285821735,0.000132558554638947,0.000127819051559988,8.4687379487418e-06,8.4687379487418e-06,4.43221338225694e-06,3.35675276641243e-06,0.781360021158442,0,0,0,0.00248546401372042,"HALLMARK_APICAL_SURFACE","kendall_tau","HN16","HN17",0.810299281201347 "HALLMARK_XENOBIOTIC_METABOLISM11",0.044946988463444,0.0394854349115014,0.0693540193498435,2.9209418852572,12.5275065406558,15.5761401619189,2.3694827411833e-06,1.0266391035251e-06,0.00184285697890759,0.000133969164594678,8.22831192212395e-05,1.43764125457697e-05,1.43764125457697e-05,3.69577643390784e-06,3.57713511447391e-06,0.00348974916932421,0,0,0,0.00283379378260623,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN16","HN17",0.0048224970894539 "HALLMARK_WNT_BETA_CATENIN_SIGNALING11",0.0368445282613217,0.0330011081660574,0.0669455263237469,1.67248471388855,14.33949363432,17.3386332187081,3.58782712692719e-06,1.59311488644775e-06,0.00227616827439777,8.5692807357928e-05,9.39089762788435e-05,1.37178534401435e-05,1.37178534401435e-05,4.30650391749162e-06,3.73271934172898e-06,0.0944287796651939,0,0,0,0.00318060914220747,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN16","HN17",0.114837895435644 "HALLMARK_KRAS_SIGNALING_DN11",0.058651630074657,0.056252546393854,0.0911002503915311,0.973522747331436,15.5356907358753,14.613998750877,4.28470672392996e-06,1.68822761787827e-06,0.00244395874388424,0.000195152063765148,0.000134936019835592,5.64408391322564e-05,5.64408391322564e-05,4.26245878522947e-06,5.5860438745686e-06,0.330293560306879,0,0,0,0.00339877832347256,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN16","HN17",0.36782691943266 "HALLMARK_COAGULATION11",0.0471657337757762,0.040956776475856,0.0743382144487467,2.84730595398993,13.1656412900768,16.9505765674175,3.49012372434456e-06,1.16507940706231e-06,0.0021575919751906,0.000146401041602463,5.65956878550676e-05,2.77602222745698e-05,2.77602222745698e-05,4.15965612571419e-06,3.7782975994209e-06,0.00440909649164523,0,0,0,0.00310642229829687,"HALLMARK_COAGULATION","kendall_tau","HN16","HN17",0.0060151942855856 "HALLMARK_HEDGEHOG_SIGNALING11",0.0491392049777658,0.043784028118017,0.0893526219706833,2.0169976559306,15.0794870755671,17.2648671128917,4.6105989367447e-06,2.33855264903435e-06,0.00263612434945301,0.000164195868252302,0.000184647684939693,8.36257107234787e-06,8.36257107234787e-06,7.01162447402506e-06,6.86634173328718e-06,0.0436957579348702,0,0,0,0.00399572419800964,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN16","HN17",0.055492668824414 "CELL_CYCLE11",0.047158913074406,0.061377518391058,0.0801677121190566,-6.36988110948147,15.623637511749,10.55376167586,3.85257868045622e-06,1.02996764441957e-06,0.00220964846183183,0.00011159115479696,0.000159213125357525,2.73890959249508e-05,2.73890959249508e-05,4.36370144453842e-06,3.06991743061591e-06,1.89174675924164e-10,0,0,0,0.00232834243530504,"CELL_CYCLE","kendall_tau","HN16","HN17",4.73339189120887e-10 "PEMT11",0.0705500071133874,0.0662761575411479,0.145703324323043,1.08730953274956,14.3712500108093,17.0115534617777,9.53536583995352e-06,5.81476184710602e-06,0.00391792390011081,0.000629660428189016,0.000637333180999185,-0.000122682838161543,-0.000122682838161543,2.72468444369042e-05,2.16996837767182e-05,0.276900037078622,0,0,0,0.00664369117905398,"PEMT","kendall_tau","HN16","HN17",0.312809263789106 "EPI_DIFF111",0.0541046684145276,0.0464511765904416,0.101193725561203,2.82950982848431,14.0829794331175,16.8271604024604,4.39061368013162e-06,2.82577605145866e-06,0.00268633388311846,0.000370826170327814,0.000219425453902264,-1.42317911591174e-05,-1.42317911591174e-05,1.10802341566691e-05,1.04834767945082e-05,0.00466193680771498,0,0,0,0.00482134044484034,"EPI_DIFF1","kendall_tau","HN16","HN17",0.00633807824956395 "EPI_DIFF211",0.0618331402556755,0.0693842542585289,0.101431886082334,-2.43200174054966,11.773650632136,10.5843174498247,7.03461685452143e-06,2.50576621433529e-06,0.00308875105323442,0.000308632720456404,0.000506895923999606,3.02739417445547e-05,3.02739417445547e-05,1.1212030651012e-05,9.06782197503029e-06,0.0150156351569941,0,0,0,0.00376309513993608,"EPI_DIFF2","kendall_tau","HN16","HN17",0.0196641280006961 "STRESS11",0.0540392788034752,0.0547433255313161,0.106209982706073,-0.222513193583007,13.5521518031678,14.7948847242707,6.51922566062622e-06,3.39209645168668e-06,0.00314822523214476,0.000344115592602641,0.000419944901604725,-3.69400405801461e-05,-3.69400405801461e-05,1.47196135026493e-05,1.20012087028427e-05,0.823914403704103,0,0,0,0.00464670938344172,"STRESS","kendall_tau","HN16","HN17",0.850357102568689 "HYPOXIA11",0.0543127658965543,0.0544872438607883,0.102302863488157,-0.0645298999183618,14.9451914204963,16.6928388566824,4.8609247514585e-06,2.34977903528932e-06,0.00268527536516235,0.000205651717182164,0.00037380635674631,-2.34444511812764e-05,-2.34444511812764e-05,1.02109884970149e-05,8.10501112296324e-06,0.948548300026281,0,0,0,0.00409208078302727,"HYPOXIA","kendall_tau","HN16","HN17",0.958959272440776 "HALLMARK_PANCREAS_BETA_CELLS12",0.0666050356191201,0.0480557469590371,0.0639359029996975,4.87521109408934,-1.5921449748462,5.14999664455052,6.72167220847496e-06,7.65496427001669e-06,0.0037916535282765,0.000305889257905532,8.73741511950151e-05,0.000160704297126313,0.000160704297126313,2.71044496187527e-06,9.40814155859101e-06,1.08692162315016e-06,0.111352133578818,2.60491119341566e-07,7.81473358024698e-07,0.00421377740245346,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN16","HN22",2.00662453504645e-06 "HALLMARK_MYOGENESIS12",0.0476061393486547,0.0420113457187662,0.0509801463228083,1.82746549732062,2.13081275639246,3.5915103111301,3.7784766480423e-06,5.49433243928768e-06,0.00304512874725027,0.00017303080561392,0.000102805099743824,8.29309657101292e-05,8.29309657101292e-05,2.40727156718617e-06,6.13612055674749e-06,0.0676298092829244,0.033104571017764,0.00032876716633834,0.000986301499015019,0.00327102197567994,"HALLMARK_MYOGENESIS","kendall_tau","HN16","HN22",0.0840725747534028 "HALLMARK_IL2_STAT5_SIGNALING12",0.0392525605896687,0.0368007893047348,0.042771081112748,0.940321567100321,2.23250041615984,2.84125835530597,2.37482431639835e-06,4.32358195375476e-06,0.00258812794702138,9.53381899377831e-05,0.000102433622976291,3.89521170954818e-05,3.89521170954818e-05,2.38391700150469e-06,4.31539605519353e-06,0.347052640145937,0.0255819077536568,0.00449358922412402,0.0134807676723721,0.00273619400383191,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN16","HN22",0.385031985671342 "HALLMARK_ESTROGEN_RESPONSE_EARLY12",0.0438919749653701,0.0417217049497595,0.0474796785442183,0.677767219604204,2.04537698081367,2.46706145752869,2.54358086016867e-06,7.60978419487775e-06,0.00318643453644452,0.000109116042581959,0.000191448351200306,4.81473631871007e-05,4.81473631871007e-05,2.97670870079062e-06,5.34727625712529e-06,0.497919298403084,0.0408177065741664,0.0136226974335345,0.0408680923006035,0.00362479242114223,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN16","HN22",0.541176612682094 "HALLMARK_BILE_ACID_METABOLISM12",0.0458022264863311,0.0435580324663076,0.0501799501681144,0.779121361568139,2.56624815631391,2.85946923500989,3.51740645064396e-06,4.67939272334531e-06,0.0028630052696405,0.000128309584024363,0.000120274109077528,6.25731447786932e-05,6.25731447786932e-05,2.81004289622873e-06,5.26286298360017e-06,0.435908227785082,0.010280524943872,0.00424350576709331,0.0127305173012799,0.00296198130496567,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN16","HN22",0.477752167637704 "HALLMARK_MITOTIC_SPINDLE12",0.0712586271397228,0.0753491428084734,0.0822364901796234,-0.81281262443845,2.70489360237875,1.55909014203628,9.62053501993632e-06,1.56059687047878e-05,0.005022599299638,0.000375913148348408,0.000536705337530741,5.4202037806041e-05,5.4202037806041e-05,1.63715793592034e-05,1.94146840478205e-05,0.41632549630882,0.00683262702359233,0.118975046536074,0.020497881070777,0.00503677424949153,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN16","HN22",0.457568956690816 "HALLMARK_INFLAMMATORY_RESPONSE12",0.0377023217422396,0.031602112600324,0.0386450082298837,2.71523624727648,0.782750421891113,4.14733048810449,2.3397521512775e-06,2.607723170317e-06,0.00222429209448636,7.81204711562053e-05,5.19463017158179e-05,4.48394023561806e-05,4.48394023561806e-05,1.35040050822738e-06,2.78380052364173e-06,0.00662285069007207,0.433773686539474,3.36374343661294e-05,0.000100912303098388,0.00232593742386256,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN16","HN22",0.00886060570139335 "HALLMARK_ESTROGEN_RESPONSE_LATE12",0.0496023578657877,0.0485605638218152,0.0543525385240797,0.288026935296279,2.2859932141781,2.07270635039133,2.951635883009e-06,1.00310686637637e-05,0.00360315202937272,0.000148344370497051,0.00022932744139746,4.88166968577049e-05,4.88166968577049e-05,4.21787812754695e-06,7.7086823524119e-06,0.773326120546628,0.0222546555484,0.0381996164199196,0.0667639666452,0.00402884929367799,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN16","HN22",0.803384733006038 "HALLMARK_ADIPOGENESIS12",0.0366311316354432,0.0330938335475744,0.0390217935185218,1.53698505168131,1.67261596640724,3.05474844868745,2.12561079217967e-06,3.07107281222877e-06,0.00227962356638293,9.68240464812096e-05,7.8459121558295e-05,3.91523374395717e-05,3.91523374395717e-05,1.94288461637978e-06,3.66582053129898e-06,0.12429696999927,0.0944029216809954,0.00225249361655333,0.00675748084965999,0.00243375803696214,"HALLMARK_ADIPOGENESIS","kendall_tau","HN16","HN22",0.149004318775883 "HALLMARK_P53_PATHWAY12",0.0493229325702962,0.0454389451888412,0.0530570297338271,1.13175067272573,1.90147880254513,2.75546764574374,4.51084387945722e-06,7.16668283262745e-06,0.00341723963340072,0.000199956815048041,0.00017434217053563,8.93844284386739e-05,8.93844284386739e-05,3.75645485850064e-06,7.54365266895986e-06,0.257739271141466,0.0572393264152067,0.00586083006737592,0.0175824902021278,0.00369588291970012,"HALLMARK_P53_PATHWAY","kendall_tau","HN16","HN22",0.292851577644797 "HALLMARK_HEME_METABOLISM12",0.0419389300627888,0.0378211023784354,0.0439379582252605,1.61033889375478,1.40419906931283,3.0392661208936,2.66807994821904e-06,3.77077605255961e-06,0.00253749009865628,0.000104623052441995,8.56395683172225e-05,5.2089972246566e-05,5.2089972246566e-05,1.92665798133003e-06,3.95059697152745e-06,0.107323892740515,0.160259578932953,0.00237155262007049,0.00711465786021148,0.00269648665096679,"HALLMARK_HEME_METABOLISM","kendall_tau","HN16","HN22",0.129184132920005 "HALLMARK_CHOLESTEROL_HOMEOSTASIS12",0.0406353709074141,0.0424846473959409,0.0476272053997877,-0.612479302778175,3.44635453123141,2.05140592448521,3.57192046936416e-06,5.44442682290112e-06,0.00300272331263893,0.000141513947856812,0.00017939811381148,5.42572230578602e-05,5.42572230578602e-05,4.01587687841071e-06,6.18427507789326e-06,0.540220687601379,0.000568204384696402,0.0402274325885861,0.00170461315408921,0.0031726556222437,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN16","HN22",0.582309375452999 "HALLMARK_NOTCH_SIGNALING12",0.03798435775946,0.0303404303219374,0.0382823506503919,2.95641129129881,0.233956631309408,3.85325872979278,2.58698557733443e-06,3.99804513530041e-06,0.00256613146830688,0.000122589772741274,6.46950864360396e-05,5.91948517865628e-05,5.91948517865628e-05,1.52233705594332e-06,4.14809979015698e-06,0.00311241747938484,0.815018647526948,0.000116556112063959,0.000349668336191877,0.00282484954696069,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN16","HN22",0.00431627707046766 "HALLMARK_ALLOGRAFT_REJECTION12",0.0388726791268356,0.0340806200565269,0.0403357191653533,2.26554382218523,1.14784657058695,3.96615271697499,2.49939148057949e-06,1.8746436659711e-06,0.00209141940952803,7.659581268006e-05,5.50542850591841e-05,4.46634940124691e-05,4.46634940124691e-05,1.52459361079537e-06,2.38730776148275e-06,0.0234793280203076,0.251031908157816,7.30420720591596e-05,0.000219126216177479,0.00214029511010591,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN16","HN22",0.0303758963167016 "HALLMARK_INTERFERON_GAMMA_RESPONSE12",0.0332405920844584,0.0290458811082174,0.0348304011818549,1.97764151968044,1.37929534159028,3.35829209058905,1.81942981706913e-06,2.5794971410895e-06,0.00209736190443105,8.16401115429953e-05,5.67061662108419e-05,3.93565523679961e-05,3.93565523679961e-05,1.2285423922165e-06,2.86686463490592e-06,0.0479691618489542,0.167803712246105,0.000784256936301242,0.00235277080890373,0.00227584601347405,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN16","HN22",0.0606577788541614 "HALLMARK_ANDROGEN_RESPONSE12",0.0409881511289962,0.0374515414794577,0.0434808614013254,1.33275525701902,1.6717295131128,2.90920699715674,2.02634532091842e-06,4.91528865310397e-06,0.00263469808024039,9.31986767095992e-05,0.000107820059472691,3.76598989426519e-05,3.76598989426519e-05,2.12336921182871e-06,4.19523975135446e-06,0.182612133215722,0.0945776716684188,0.0036234685915375,0.0108704057746125,0.00290667492365446,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN16","HN22",0.211995921679851 "HALLMARK_TNFA_SIGNALING_VIA_NFKB12",0.0432197203320425,0.0380961279836012,0.0442900233205321,1.74371574561529,0.760686259871631,2.90525115804073,3.18249682313687e-06,5.35121916971442e-06,0.0029212524698922,0.000119732711093041,0.000111967355873917,6.97585958955292e-05,6.97585958955292e-05,1.87971344532271e-06,4.44527703871348e-06,0.0812086683774347,0.446844483584748,0.00366958510405624,0.0110087553121687,0.00320425857361667,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN16","HN22",0.0996883027263707 "HALLMARK_PEROXISOME12",0.040062802093352,0.0377547296106296,0.0431210796429961,0.891497115781835,2.01479945056106,2.68959377241419,2.81165981892086e-06,3.7911824798885e-06,0.00256959963784426,0.000102119978279777,9.95256133506863e-05,5.11604410283291e-05,5.11604410283291e-05,2.20404069638655e-06,3.88093066077922e-06,0.372662538186441,0.0439256666503827,0.00715390447671482,0.0214617134301445,0.00271928153192676,"HALLMARK_PEROXISOME","kendall_tau","HN16","HN22",0.411890173785014 "HALLMARK_INTERFERON_ALPHA_RESPONSE12",0.0422965153078158,0.0372582289083985,0.0435231464960243,1.79496377997761,0.83949825861406,2.91063285266783,3.38354443073285e-06,4.39515120262435e-06,0.00278903130734619,0.00014127546476153,0.000103880801044878,7.47511817950648e-05,7.47511817950648e-05,2.03495343136697e-06,4.53293141313348e-06,0.07265947090958,0.401189765984794,0.003606975863373,0.010820927590119,0.00305407777904789,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN16","HN22",0.0896616346166486 "HALLMARK_TGF_BETA_SIGNALING12",0.0372656624583279,0.0323103764477756,0.0379870376118676,1.88801536289949,0.557295278005939,3.03023128805859,2.90570695637353e-06,3.8828206755302e-06,0.0026054803073337,9.31601118644204e-05,7.55739439760063e-05,5.81732924136733e-05,5.81732924136733e-05,1.5755277807615e-06,3.40941225502786e-06,0.0590238880325868,0.57732570140227,0.0024436652658375,0.00733099579751251,0.00275358779248633,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN16","HN22",0.073842651410981 "HALLMARK_FATTY_ACID_METABOLISM12",0.0348902736746205,0.032447008842743,0.0374445047337012,1.0342884937951,1.89405795536297,2.70593254470823,2.03476470509329e-06,3.4455372688468e-06,0.00234100447969245,8.37242169650649e-05,8.21911704738042e-05,3.88028341830634e-05,3.88028341830634e-05,1.71858596812379e-06,3.31091549053525e-06,0.301001314310237,0.0582173176539853,0.00681128800051067,0.020433864001532,0.00252970648297359,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN16","HN22",0.337764833615304 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE12",0.0551920273248241,0.0517290058487894,0.0591159855643818,0.921767687918453,1.80822774107014,2.3296770829897,4.51645866706696e-06,9.49810345496811e-06,0.00374360282642738,0.000235759490629039,0.000202491863433425,8.7498224800202e-05,8.7498224800202e-05,4.60914971733713e-06,9.95408049196368e-06,0.356649765157211,0.0705710627439438,0.0198232246636443,0.0594696739909328,0.00403621046366373,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN16","HN22",0.395306431503186 "HALLMARK_MTORC1_SIGNALING12",0.0476355014509166,0.0474205881995077,0.0533790445897377,0.0669595344494838,2.41674283389472,2.13847229613039,4.06873493840804e-06,6.13279047637927e-06,0.00319398268855473,0.000180716359479908,0.000210186820796931,5.02725592798955e-05,5.02725592798955e-05,5.54805472033027e-06,7.66354855460097e-06,0.946613917696975,0.0156600767063204,0.0324784302848611,0.0469802301189612,0.00335853866223453,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN16","HN22",0.958018904657179 "HALLMARK_UV_RESPONSE_UP12",0.0412643940728578,0.0407477310721495,0.0457962690259698,0.184509087991886,2.43234116984431,2.17979157770174,2.75227852461662e-06,4.98886132111835e-06,0.00278229039565157,0.000119172721351831,0.000144090173349174,4.02959044993416e-05,4.02959044993416e-05,3.3714175478114e-06,5.26415490268821e-06,0.853614098366018,0.015001569370775,0.0292729145360826,0.045004708112325,0.00297230725094845,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN16","HN22",0.878259124828029 "HALLMARK_ANGIOGENESIS12",0.0582638689278528,0.0434293491407863,0.0562785677651342,3.67587616407391,-1.09140273105073,4.40277838523973,7.46828796600882e-06,8.71811740362774e-06,0.00402323319851541,0.000295078498588256,0.000163876978933992,0.000173817720668858,0.000173817720668858,3.20889298411031e-06,8.41725766248995e-06,0.000237034490413901,0.275095711228423,1.06873321450429e-05,3.20619964351287e-05,0.00450537783316029,"HALLMARK_ANGIOGENESIS","kendall_tau","HN16","HN22",0.000356005824682947 "HALLMARK_MYC_TARGETS_V112",0.0690738818985687,0.0713302600555415,0.0778733556791202,-0.488986525823851,2.50362391059051,1.73028849341774,1.04854037845168e-05,1.07072596481042e-05,0.00460354900404254,0.000368882131442663,0.000485353507548608,0.00013323946222519,0.00013323946222519,1.22530790902853e-05,1.4199784585802e-05,0.624851236214371,0.0122928626921623,0.0835787443406117,0.036878588076487,0.00478846425822425,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN16","HN22",0.662601491242651 "HALLMARK_DNA_REPAIR12",0.0546771694659019,0.0568325963390769,0.0622366966091076,-0.596795176727469,2.68417696792221,1.83982374762393,5.63192774094414e-06,7.31222805731788e-06,0.00359779874343494,0.000190951273773452,0.000329515311577905,5.784202997165e-05,5.784202997165e-05,7.83171261898493e-06,8.52768651153074e-06,0.550644138588592,0.00727086086296125,0.0657941177648125,0.0218125825888837,0.00379942521312776,"HALLMARK_DNA_REPAIR","kendall_tau","HN16","HN22",0.591917282431613 "HALLMARK_KRAS_SIGNALING_UP12",0.0463152704358734,0.0422857685942802,0.0489405348268846,1.35458990166342,1.67611976124647,3.0790383798882,3.14824017999967e-06,5.6006142329224e-06,0.00295784624565275,0.00011492014701189,0.00013127476966806,6.24225949687734e-05,6.24225949687734e-05,2.35321721109342e-06,4.57127466263992e-06,0.175548252628304,0.093714736749166,0.00207669926437126,0.00623009779311379,0.00324446525587249,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN16","HN22",0.20500967734944 "HALLMARK_HYPOXIA12",0.0383701202188002,0.0358656907955244,0.0414852550121896,0.942891192676453,2.13793125908661,2.66335375361763,2.221174379618e-06,4.73378368601892e-06,0.00263722544839021,0.000103511082520525,0.000107884819840524,4.54860220485622e-05,4.54860220485622e-05,2.02307928357162e-06,4.35192221891951e-06,0.345736560270199,0.0325223227654017,0.00773660333658222,0.0232098100097466,0.00289985417017289,"HALLMARK_HYPOXIA","kendall_tau","HN16","HN22",0.383934083926113 "HALLMARK_SPERMATOGENESIS12",0.0516480519022084,0.0484391956441972,0.0550274965434654,1.09666346772352,1.8380682027988,2.78061361801226,2.83664405871693e-06,5.62493307005152e-06,0.00290887901583556,0.000128716355382195,0.000142311130241758,4.55295929805183e-05,4.55295929805183e-05,3.28039483146156e-06,5.51391148918625e-06,0.272788531845849,0.0660523559436172,0.00542562701795446,0.0162768810538634,0.00315657260351312,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN16","HN22",0.308757760780288 "HALLMARK_OXIDATIVE_PHOSPHORYLATION12",0.062625568139051,0.0562728269757935,0.065038724360603,1.72244822966729,1.11397628246215,3.06645020024896,6.46427488811382e-06,7.03857691010271e-06,0.00367462267426419,0.000237590479823253,0.000197965368271065,0.000122147251599578,0.000122147251599578,4.59265889625838e-06,8.07186028263478e-06,0.0849883533040636,0.265289361702247,0.00216616888885657,0.0064985066665697,0.00389339316171944,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN16","HN22",0.103786400296551 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION12",0.0474499459065953,0.0393644336194575,0.0485720084622426,2.80243797883234,0.740190401495417,4.20968158878014,4.23054643479154e-06,3.99366423762949e-06,0.00286778846368086,0.00015587648633933,0.000104861107619283,9.06881297383067e-05,9.06881297383067e-05,2.19798527488094e-06,4.6840093452991e-06,0.00507179672553759,0.459184470922286,2.55730835543311e-05,7.67192506629932e-05,0.00310937821521577,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN16","HN22",0.00687939209830704 "HALLMARK_MYC_TARGETS_V212",0.0555108022606297,0.0540463132252193,0.0608518553762345,0.404147917486875,2.08771853091077,2.13373372302912,6.10330512960847e-06,6.92750611468053e-06,0.00360982149756591,0.000288233934099843,0.000256232761738463,0.000104212925091032,0.000104212925091032,6.44500378009738e-06,1.00729055904587e-05,0.68610395028567,0.0368232322444786,0.0328645839100081,0.0985937517300244,0.00385278817414054,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN16","HN22",0.718484635383747 "HALLMARK_E2F_TARGETS12",0.0606869887923041,0.063621740375399,0.0691046946620589,-0.741840271356851,2.54046251479066,1.61292944717625,7.02347697069406e-06,8.52679466606864e-06,0.00394338327287149,0.000242432126412925,0.000375160472711683,4.81317000915159e-05,4.81317000915159e-05,1.08789779012309e-05,1.14557598627798e-05,0.458184117715174,0.0110705960148128,0.106759836732013,0.0332117880444383,0.00396077805673088,"HALLMARK_E2F_TARGETS","kendall_tau","HN16","HN22",0.501698810459073 "HALLMARK_IL6_JAK_STAT3_SIGNALING12",0.0303832080964805,0.0269314635998066,0.031184828992193,1.86005179217942,0.77790474152175,3.14259722786291,1.3465459025822e-06,1.99716914284304e-06,0.00182858279698384,4.40725432739953e-05,4.39995182878454e-05,2.44084844782521e-05,2.44084844782521e-05,9.61903913754464e-07,1.73184169577411e-06,0.0628781987161431,0.43662517281902,0.0016745608830615,0.00502368264918451,0.00194883365020797,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN16","HN22",0.0784976238749302 "HALLMARK_PROTEIN_SECRETION12",0.0515964206290374,0.0456307143731712,0.0541134708145675,1.79731979345527,1.30676604789634,3.11926608898105,5.34764436382762e-06,5.56960087161897e-06,0.00330412548724267,0.000224268614829757,0.00014817823943594,0.000109010411124616,0.000109010411124616,3.61012092547699e-06,7.29552735175059e-06,0.0722848656731834,0.191292179406065,0.00181302150165052,0.00543906450495157,0.00350927830007414,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN16","HN22",0.0892930693609912 "HALLMARK_UV_RESPONSE_DN12",0.0406298318270149,0.0352100956537646,0.0425747960959229,1.99861780454207,1.33220079204219,3.59458979512429,2.52202161977081e-06,4.73152395225638e-06,0.0026932407192873,0.000106184935807815,0.000113310689351456,5.21545040089043e-05,5.21545040089043e-05,2.03149284676156e-06,4.09770098576663e-06,0.0456497224719554,0.182794216366916,0.000324903075832772,0.000974709227498316,0.00301326331882569,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN16","HN22",0.0577869468536271 "HALLMARK_APOPTOSIS12",0.0417382243773198,0.0385908379564059,0.0450710152401438,1.09818502185669,1.9679705610888,2.77264199744377,2.60768344461307e-06,5.50621069516156e-06,0.00284848979983686,0.000122211383437031,0.00012806304027786,4.68090926143017e-05,4.68090926143017e-05,2.76799855933992e-06,5.36243371907012e-06,0.272123705263611,0.0490714250434723,0.00556032545852547,0.0166809763755764,0.00309155252175713,"HALLMARK_APOPTOSIS","kendall_tau","HN16","HN22",0.30830200133912 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY12",0.0357281524484558,0.0325616252866878,0.0373085769336594,1.37719190445273,1.20899045750144,2.60284495561771,1.90591897197266e-06,3.28069394881796e-06,0.00227741364727417,8.26356117471297e-05,7.7674355512161e-05,3.75179108864996e-05,3.75179108864996e-05,1.60884138377264e-06,3.226082503136e-06,0.168452924096218,0.226666511480913,0.00924537539579817,0.0277361261873945,0.00247432259482804,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN16","HN22",0.197311393164495 "HALLMARK_COMPLEMENT12",0.0341583323623498,0.030843049723423,0.0360599437969429,1.50194972499732,1.56252332999308,3.04308085416777,1.64919394511451e-06,3.12306461555391e-06,0.00218454996753758,6.76749440175872e-05,7.21622125157057e-05,3.24407221572319e-05,3.24407221572319e-05,1.38112099918784e-06,2.83898286515656e-06,0.133110093277473,0.118164754224516,0.00234169405951468,0.00702508217854403,0.00238405749571216,"HALLMARK_COMPLEMENT","kendall_tau","HN16","HN22",0.15843873450841 "HALLMARK_APICAL_JUNCTION12",0.038766205271832,0.0344037449746954,0.040551957919554,1.75726052891533,1.4402705524388,3.23717301130256,1.95465209739998e-06,4.10832660081842e-06,0.00246231165741025,8.22301355463723e-05,7.86720997062338e-05,4.14755004619943e-05,4.14755004619943e-05,1.43728518880152e-06,3.50716476434543e-06,0.0788734123241195,0.149790869301214,0.00120720198883695,0.00362160596651084,0.00269327581943273,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN16","HN22",0.0971257936054079 "HALLMARK_GLYCOLYSIS12",0.0481756791191288,0.0467165364182854,0.0534810783985406,0.431595959991913,2.46876953316653,2.34169964012198,3.60136449004008e-06,7.72849239191954e-06,0.00336598527655122,0.000178560566457622,0.000192344411243438,5.70559024882667e-05,5.70559024882667e-05,4.51822459446975e-06,8.24477082954247e-06,0.666035095239549,0.0135578505743283,0.0191961564400136,0.040673551722985,0.00359549548279392,"HALLMARK_GLYCOLYSIS","kendall_tau","HN16","HN22",0.699336850001527 "HALLMARK_PI3K_AKT_MTOR_SIGNALING12",0.0361791997405679,0.0346863386814961,0.0389907425592122,0.642434304282911,1.96990365262965,2.27148330091716,2.06073476183068e-06,3.23911072966883e-06,0.00230213932929775,9.29938187123338e-05,9.26024890815511e-05,3.92566031636756e-05,3.92566031636756e-05,1.93703941867152e-06,3.49092993287862e-06,0.520591232193925,0.0488494137471638,0.0231177367431936,0.0693532102295809,0.00250971933941393,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN16","HN22",0.562697875974316 "HALLMARK_G2M_CHECKPOINT12",0.0699030363083021,0.0742944461661677,0.0803934633517927,-0.921066577624873,2.61703529456665,1.46373112552445,9.48428215342853e-06,1.31471028576815e-05,0.00475724552773031,0.000341094535019354,0.000514763749426273,4.69661144424137e-05,4.69661144424137e-05,1.59681980490351e-05,1.72618939136315e-05,0.357015668456949,0.00886971695189365,0.143267427526408,0.0266091508556809,0.00471764514033675,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN16","HN22",0.395339384280012 "HALLMARK_APICAL_SURFACE12",0.0390069805726537,0.035877267021045,0.0416534150807093,1.01702668776466,1.71392177960319,2.67363234981199,2.65497302377326e-06,6.71490711194871e-06,0.00306102599396378,0.000105878171869226,0.000148112635178748,5.51434266505191e-05,5.51434266505191e-05,2.28418695021212e-06,4.56738105622917e-06,0.309140733808018,0.0865430924968618,0.00750346616941377,0.0225103985082413,0.00345379582723262,"HALLMARK_APICAL_SURFACE","kendall_tau","HN16","HN22",0.34623762186498 "HALLMARK_XENOBIOTIC_METABOLISM12",0.044946988463444,0.0422634537163814,0.0492159281434989,0.975477305718264,2.50720793799554,3.04597643300338,2.3694827411833e-06,5.09849952751831e-06,0.0027327609241757,0.000108073578811459,0.000128617960449937,3.85777583757786e-05,3.85777583757786e-05,2.79907418202109e-06,5.10985603506223e-06,0.329323553541292,0.012168910069726,0.00231926013010586,0.00695778039031758,0.00294623526323658,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN16","HN22",0.367094311814748 "HALLMARK_WNT_BETA_CATENIN_SIGNALING12",0.0368445282613217,0.0362668424128643,0.0400568334513469,0.180741690241373,1.90140139530283,1.77735069315724,3.58782712692719e-06,6.52784107414752e-06,0.00318051382658128,0.000119246708069303,0.00018634428462322,7.24034250152226e-05,7.24034250152226e-05,2.75421038663245e-06,4.44705398421603e-06,0.856570333576919,0.0572494569262862,0.0755105578869348,0.171748370778859,0.00358751144328203,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN16","HN22",0.880530342907742 "HALLMARK_KRAS_SIGNALING_DN12",0.058651630074657,0.054607160153672,0.0632050877730904,1.19980491005588,2.27779373268831,3.20783472233544,4.28470672392996e-06,6.97852727309232e-06,0.00335607419420702,0.000161857493750475,0.000172960267677894,7.3157983587356e-05,7.3157983587356e-05,3.89626082191263e-06,7.08395497120597e-06,0.230215116805744,0.0227388699168891,0.00133738331857658,0.00401214995572974,0.00354534418269249,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN16","HN22",0.263358927396454 "HALLMARK_COAGULATION12",0.0471657337757762,0.0407437596429873,0.049260474574266,2.35574401790895,1.34771009859603,3.97209497206162,3.49012372434456e-06,3.84145204324344e-06,0.00270768827001706,0.000132375195530696,9.35687223512062e-05,6.78940684928036e-05,6.78940684928036e-05,2.31583693922371e-06,4.49732254001617e-06,0.0184856513669067,0.177751642756724,7.12433035086057e-05,0.000213729910525817,0.00287742479146304,"HALLMARK_COAGULATION","kendall_tau","HN16","HN22",0.0240743366638785 "HALLMARK_HEDGEHOG_SIGNALING12",0.0491392049777658,0.045164386791606,0.0523672932304653,1.18080887788836,1.88772605977075,2.8678613356449,4.6105989367447e-06,6.62058571830363e-06,0.0033512959664954,0.000169479502959567,0.000155511283985683,9.7273776491684e-05,9.7273776491684e-05,2.8242389420862e-06,6.20810987763819e-06,0.237678656469613,0.0590627360005882,0.00413256610312418,0.0123976983093725,0.00361214697329312,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN16","HN22",0.270580929340043 "CELL_CYCLE12",0.047158913074406,0.0448368027231437,0.0503526566409748,0.834581571068112,1.67431745370177,2.51588825545087,3.85257868045622e-06,3.78897496774541e-06,0.00276433602302644,0.000135606011233008,0.000152111128887763,6.21649323959057e-05,6.21649323959057e-05,3.53851756876347e-06,4.70665349983126e-06,0.403953341939958,0.0940682260761809,0.0118732821101681,0.0356198463305044,0.00292570161398856,"CELL_CYCLE","kendall_tau","HN16","HN22",0.44563708266547 "PEMT12",0.0705500071133874,0.0597734070515726,0.0728392697241082,2.20716409340349,0.916020044896215,3.35322755325526,9.53536583995352e-06,1.42039774073158e-05,0.00487230368996734,0.000424186524251019,0.000279479528880208,0.000207900232474849,0.000207900232474849,6.14570224406501e-06,1.50827390025588e-05,0.0273025973232897,0.35965638155421,0.000798750080000188,0.00239625024000056,0.00528024713283686,"PEMT","kendall_tau","HN16","HN22",0.0350522428517343 "EPI_DIFF112",0.0541046684145276,0.0533030921665019,0.0594481565566901,0.167315349180574,2.17735657873021,1.90915369848755,4.39061368013162e-06,1.84612582303584e-05,0.00478036315675807,0.000188083924387362,0.000470966534196906,9.00758180260837e-05,9.00758180260837e-05,5.92269103244083e-06,1.02602703777235e-05,0.867121927477287,0.0294539727636616,0.0562422672515122,0.0883619182909847,0.00561463602684734,"EPI_DIFF1","kendall_tau","HN16","HN22",0.889821454374598 "EPI_DIFF212",0.0618331402556755,0.0587074275010466,0.0665205134550619,0.699253398338414,1.76049636240181,2.17402912277967,7.03461685452143e-06,1.28469232228055e-05,0.00445887206335043,0.000328315790779432,0.000329025975103377,0.00013196494257089,0.00013196494257089,6.98906243048881e-06,1.28155971139784e-05,0.484393684873326,0.0783236837319061,0.029702948137559,0.0891088444126771,0.00487754323778245,"EPI_DIFF2","kendall_tau","HN16","HN22",0.52745090130651 "STRESS12",0.0540392788034752,0.0473715758738033,0.0558976811077477,1.59590426141797,0.943540604465212,2.83624820277721,6.51922566062622e-06,1.08365364877628e-05,0.0041660247416919,0.000249809931090927,0.000223740604733231,0.000144458457309129,0.000144458457309129,3.779343906186e-06,8.93676336142247e-06,0.110510169972897,0.345404456479525,0.00456469564061157,0.0136940869218347,0.00458121195942927,"STRESS","kendall_tau","HN16","HN22",0.132747660764175 "HYPOXIA12",0.0543127658965543,0.0503883995450113,0.0584015936720399,1.07113458129483,2.05196151273419,2.76314597146762,4.8609247514585e-06,8.46211898902023e-06,0.0036500744842371,0.00022279897667524,0.000198081607152629,0.00010282329518347,0.00010282329518347,3.87062812758095e-06,8.31014863438234e-06,0.2841089211043,0.0401734029310983,0.00572471581012945,0.0171741474303884,0.00400749511993898,"HYPOXIA","kendall_tau","HN16","HN22",0.320030738715188 "HALLMARK_PANCREAS_BETA_CELLS13",0.0666050356191201,0.0469384018164506,0.125807617992434,3.73189469619282,14.8704594373553,12.9062510761479,6.72167220847496e-06,2.09499533501288e-05,0.00526038264374406,0.000181265237602042,0.000124559211905299,-6.10135970980172e-05,-6.10135970980172e-05,1.57501190346635e-05,3.72434837293612e-05,0.000190044949244683,0,0,0,0.00258653928109429,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN16","HN28",0.000286897124918803 "HALLMARK_MYOGENESIS13",0.0476061393486547,0.0386590268415247,0.1008084824673,2.20103579123723,25.8732119954492,14.7648861070297,3.7784766480423e-06,1.26453864279999e-05,0.00405263655859272,5.39638688340748e-05,4.50390221921389e-05,2.67810622444726e-05,2.67810622444726e-05,4.12825163593149e-06,1.76179901286656e-05,0.0277334901623925,0,0,0,0.00297736526517442,"HALLMARK_MYOGENESIS","kendall_tau","HN16","HN28",0.03556661333803 "HALLMARK_IL2_STAT5_SIGNALING13",0.0392525605896687,0.0253116190709646,0.0765584967088966,4.40251766810797,23.7279514711494,15.8060196290426,2.37482431639835e-06,7.55242920943943e-06,0.00315075443756536,1.84931371316329e-05,2.70027690289923e-05,1.63649598456514e-05,1.63649598456514e-05,2.37192559045145e-06,1.04121073175273e-05,1.07001873037582e-05,0,0,0,0.00186200451515631,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN16","HN28",1.79251000986035e-05 "HALLMARK_ESTROGEN_RESPONSE_EARLY13",0.0438919749653701,0.0298062875352372,0.0951909754889183,4.0820348551767,26.6727128228318,18.431562937742,2.54358086016867e-06,9.26342798990488e-06,0.00343613283358975,3.0839860270665e-05,6.05366277398184e-05,1.51843420171296e-05,1.51843420171296e-05,3.5989923166493e-06,1.24842629312517e-05,4.46430993430447e-05,0,0,0,0.00247511493275183,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN16","HN28",7.06598719076992e-05 "HALLMARK_BILE_ACID_METABOLISM13",0.0458022264863311,0.0274662946919044,0.0960715402058583,5.4130400748852,23.6691300110159,20.0352381957822,3.51740645064396e-06,7.85682180237724e-06,0.00337256997748322,3.06974108041404e-05,2.3066599875424e-05,1.80502545874244e-06,1.80502545874244e-06,4.41067277111496e-06,1.16253448809277e-05,6.19636155718695e-08,0,0,0,0.00193736633293708,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN16","HN28",1.27616833472011e-07 "HALLMARK_MITOTIC_SPINDLE13",0.0712586271397228,0.0398244882951342,0.113341820749229,6.58303208073014,20.4542040883159,17.8107261780546,9.62053501993632e-06,1.30803230487055e-05,0.00476454174802172,0.000289979159307919,1.26747810970575e-05,0.00017538510724395,0.00017538510724395,4.13303842134751e-06,1.69379063671288e-05,4.6094905670202e-11,0,0,0,0.00427659299636487,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN16","HN28",1.20729641577188e-10 "HALLMARK_INFLAMMATORY_RESPONSE13",0.0377023217422396,0.0292877915074263,0.0854320877608045,2.17057633209445,27.9890054428613,13.4524499752323,2.3397521512775e-06,1.25885398267357e-05,0.00386371478994157,2.04825736984625e-05,5.73948629461491e-05,2.16559177273444e-05,2.16559177273444e-05,2.80806210783163e-06,1.73184101851385e-05,0.0299632127886624,0,0,0,0.00260632301268922,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN16","HN28",0.0383842464482212 "HALLMARK_ESTROGEN_RESPONSE_LATE13",0.0496023578657877,0.0337243534746905,0.105704156301949,4.38713841712867,27.149619606578,18.0369952632354,2.951635883009e-06,1.00470932534805e-05,0.00360537503409694,4.39317524492666e-05,7.02150602661534e-05,1.97552736479504e-05,1.97552736479504e-05,4.16998224201035e-06,1.58254943697594e-05,1.14851704022811e-05,0,0,0,0.00258089203710357,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN16","HN28",1.91582416923158e-05 "HALLMARK_ADIPOGENESIS13",0.0366311316354432,0.0239024390243902,0.0839894005325619,3.95055420737413,29.5394561047884,18.6769129308459,2.12561079217967e-06,8.15568455239219e-06,0.00320644590544919,2.32469632261024e-05,3.57625528200657e-05,1.51757783839802e-05,1.51757783839802e-05,2.47031676522059e-06,1.02502370807968e-05,7.79704353159882e-05,0,0,0,0.00224326488607032,"HALLMARK_ADIPOGENESIS","kendall_tau","HN16","HN28",0.000121287343824871 "HALLMARK_P53_PATHWAY13",0.0493229325702962,0.0312095845079054,0.11469587718738,4.18831921199573,29.0933074783321,18.539234256665,4.51084387945722e-06,1.40924422171878e-05,0.00431315268645164,3.30921785286886e-05,4.52980173948781e-05,2.01055656359559e-05,2.01055656359559e-05,4.9490526703936e-06,2.01790108645744e-05,2.81028051161147e-05,0,0,0,0.00279361506925428,"HALLMARK_P53_PATHWAY","kendall_tau","HN16","HN28",4.54592831039215e-05 "HALLMARK_HEME_METABOLISM13",0.0419389300627888,0.0262893736977571,0.0939679072103907,4.64567234224251,27.8735677467391,19.1042000662744,2.66807994821904e-06,8.57959558686389e-06,0.00335375543757784,2.62874959213056e-05,2.68695056662594e-05,5.49293432590067e-06,5.49293432590067e-06,3.38421907760078e-06,1.24500126674884e-05,3.38970650970438e-06,0,0,0,0.00204818992808483,"HALLMARK_HEME_METABOLISM","kendall_tau","HN16","HN28",5.94082690821513e-06 "HALLMARK_CHOLESTEROL_HOMEOSTASIS13",0.0406353709074141,0.0266793689780659,0.102624369945302,3.93554193741588,28.8770087530751,19.4532900264736,3.57192046936416e-06,8.90322310898626e-06,0.00353201692781199,3.97225023821245e-05,8.23209114786706e-05,2.89518157929663e-05,2.89518157929663e-05,4.50813122944876e-06,1.51409578002404e-05,8.30091667036736e-05,0,0,0,0.0030211432349878,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN16","HN28",0.000128784670242111 "HALLMARK_NOTCH_SIGNALING13",0.03798435775946,0.0241787962234461,0.0774987256346893,3.86991419690018,20.7170996723469,16.5681863762831,2.58698557733443e-06,1.00394118103095e-05,0.00355336423515012,7.57965554493293e-05,3.07614295426226e-05,1.53876464108315e-05,1.53876464108315e-05,3.53791180872307e-06,1.02568858340513e-05,0.0001088736641921,0,0,0,0.00238887795396349,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN16","HN28",0.000166930155267157 "HALLMARK_ALLOGRAFT_REJECTION13",0.0388726791268356,0.023572820941242,0.0683582883694981,5.26783687299421,18.9974263406563,15.2650925393304,2.49939148057949e-06,5.83609580121254e-06,0.00288712439666046,3.70902789988432e-05,1.15680269943286e-05,1.76607310290169e-05,1.76607310290169e-05,2.30896601400139e-06,8.50746647488516e-06,1.38040687547303e-07,0,0,0,0.0016995265621545,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN16","HN28",2.77023632347488e-07 "HALLMARK_INTERFERON_GAMMA_RESPONSE13",0.0332405920844584,0.0241889664686802,0.0890055212377089,2.80901957241696,33.0841430260632,18.8010628637089,1.81942981706913e-06,8.46406702391754e-06,0.00320678917937969,2.9599226439473e-05,5.2952670495033e-05,1.39652558963184e-05,1.39652558963184e-05,2.74107389888621e-06,1.17852161096103e-05,0.00496926254100272,0,0,0,0.00272336355244077,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN16","HN28",0.00674809786168498 "HALLMARK_ANDROGEN_RESPONSE13",0.0409881511289962,0.0239950726779995,0.0773155116954499,5.61734484262941,20.5245768389466,17.3910386664297,2.02634532091842e-06,7.0249369991801e-06,0.00300853491256102,2.63478952325681e-05,6.38973095161048e-05,1.63869792045167e-05,1.63869792045167e-05,3.03270330464841e-06,9.30018480379348e-06,1.93914169166476e-08,0,0,0,0.00203175246288724,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN16","HN28",4.17661287435486e-08 "HALLMARK_TNFA_SIGNALING_VIA_NFKB13",0.0432197203320425,0.0342310332148548,0.102274443326215,2.00536541635626,26.6408045396966,14.6026093620816,3.18249682313687e-06,1.68086850490115e-05,0.00447114994963806,2.86082877755164e-05,5.89705555114218e-05,3.72695354183741e-06,3.72695354183741e-06,4.8137674721392e-06,2.16125687647821e-05,0.044923996085563,0,0,0,0.00297314788943661,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN16","HN28",0.0569295467636013 "HALLMARK_PEROXISOME13",0.040062802093352,0.0219372901895781,0.0871069535897859,6.32460020347195,25.432008019072,23.4279576416909,2.81165981892086e-06,5.30157815211407e-06,0.00284837461915299,3.00182434920162e-05,2.34471291646887e-05,8.60111368328892e-06,8.60111368328892e-06,3.32176339494497e-06,7.63788187315984e-06,2.53889131940355e-10,0,0,0,0.00188660285321285,"HALLMARK_PEROXISOME","kendall_tau","HN16","HN28",6.31233867149804e-10 "HALLMARK_INTERFERON_ALPHA_RESPONSE13",0.0422965153078158,0.0345020673954166,0.118394195967441,1.720960347878,32.2526831652937,18.0652916935231,3.38354443073285e-06,1.70294466087196e-05,0.00451807381961079,4.99176588976968e-05,9.71542384775627e-05,1.7561048520064e-05,1.7561048520064e-05,5.46687077543297e-06,2.14651493812645e-05,0.0852580194693444,0,0,0,0.00399027789461974,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN16","HN28",0.104007708398287 "HALLMARK_TGF_BETA_SIGNALING13",0.0372656624583279,0.0321453529000699,0.0930855539399578,1.18612994332253,26.8624140436946,14.2735338673766,2.90570695637353e-06,1.5629228657156e-05,0.00430522190061436,3.18415830704282e-05,5.21223166156902e-05,7.2314152040568e-06,7.2314152040568e-06,4.21805229891432e-06,1.81282403150894e-05,0.235570987148316,0,0,0,0.003144632410329,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN16","HN28",0.268441357448081 "HALLMARK_FATTY_ACID_METABOLISM13",0.0348902736746205,0.0245431376751887,0.087418955083201,3.35140345888796,31.4323959792967,19.4726731950841,2.03476470509329e-06,7.39729793394906e-06,0.00307116633203777,1.76475823718868e-05,3.51634926807282e-05,7.95519527383879e-06,7.95519527383879e-06,2.69278835080594e-06,1.03259619988128e-05,0.000804030677986844,0,0,0,0.00237062066107679,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN16","HN28",0.00116445822329129 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE13",0.0551920273248241,0.031972172520953,0.117640417322657,5.00716340793355,26.3927138178811,20.6894789512037,4.51645866706696e-06,1.68883444064149e-05,0.00462653251079919,5.86228845266216e-05,3.00014390220548e-05,1.02122946715666e-05,1.02122946715666e-05,5.49853496731446e-06,1.70451240299453e-05,5.52380301499511e-07,0,0,0,0.00269693355467918,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN16","HN28",1.04943333532056e-06 "HALLMARK_MTORC1_SIGNALING13",0.0476355014509166,0.0270704743228337,0.0917976260553886,5.83588733439415,26.0583509957288,19.0786027440689,4.06873493840804e-06,8.24906834099525e-06,0.00350967281657469,4.74533697609504e-05,2.76923093124361e-05,4.6866593080873e-05,4.6866593080873e-05,2.77214299616096e-06,1.14101203042741e-05,5.35050426186956e-09,0,0,0,0.00243461800601835,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN16","HN28",1.1894504748504e-08 "HALLMARK_UV_RESPONSE_UP13",0.0412643940728578,0.0291982997333115,0.0919049379605003,3.73323107044932,28.4648939814208,19.0458108625347,2.75227852461662e-06,7.59405024111176e-06,0.00321657096388815,4.76294287072992e-05,4.45695220944869e-05,2.5651392610009e-05,2.5651392610009e-05,3.06502818372564e-06,1.07399705522998e-05,0.000189039019515391,0,0,0,0.00261906547715589,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN16","HN28",0.000285745355976992 "HALLMARK_ANGIOGENESIS13",0.0582638689278528,0.0353735965931088,0.118497979748409,3.92912893188887,21.3536098694839,14.9556119272017,7.46828796600882e-06,2.63715183083295e-05,0.00581719917781215,0.000196390289133977,2.29631201679476e-05,5.21415474599597e-05,5.21415474599597e-05,7.85687250842859e-06,3.07921756994653e-05,8.52541223563819e-05,0,0,0,0.00355388383736608,"HALLMARK_ANGIOGENESIS","kendall_tau","HN16","HN28",0.000131919536698822 "HALLMARK_MYC_TARGETS_V113",0.0690738818985687,0.0414086941234876,0.14785240653158,5.4241338902011,25.2382547193359,22.873418167479,1.04854037845168e-05,1.54285546639395e-05,0.00509057545356675,0.000150816915909711,3.98202433567682e-05,6.98944175626087e-05,6.98944175626087e-05,9.64309748096505e-06,2.15559822275642e-05,5.82362191803298e-08,0,0,0,0.00387622752025963,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN16","HN28",1.20393845444889e-07 "HALLMARK_DNA_REPAIR13",0.0546771694659019,0.0348584342486781,0.134971954836263,4.78829414828075,29.1308872422409,22.939137965124,5.63192774094414e-06,1.13993686020456e-05,0.00412689911955572,7.5030654189269e-05,0.000109700856321816,3.31372711171018e-05,3.31372711171018e-05,7.49743964661377e-06,1.89472061044311e-05,1.68204980921516e-06,0,0,0,0.00366817182805668,"HALLMARK_DNA_REPAIR","kendall_tau","HN16","HN28",3.02923518474277e-06 "HALLMARK_KRAS_SIGNALING_UP13",0.0463152704358734,0.0337291285201568,0.0888743168632826,3.29485691333283,23.8383586874954,15.5365751210099,3.14824017999967e-06,1.13436694209851e-05,0.00380682408327266,3.55848590841389e-05,3.52626163261129e-05,2.52429760060771e-05,2.52429760060771e-05,3.08735969789973e-06,1.24980889447693e-05,0.000984718064669377,0,0,0,0.00251414074575623,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN16","HN28",0.0014156826944391 "HALLMARK_HYPOXIA13",0.0383701202188002,0.0261233607059689,0.0813236053161721,4.04077604696533,25.3429785007374,16.7942348968675,2.221174379618e-06,6.86453746230574e-06,0.00301425145631942,2.59883689132752e-05,5.05705247045296e-05,1.86018791963178e-05,1.86018791963178e-05,2.77264198225276e-06,1.07034274039736e-05,5.32746151473695e-05,0,0,0,0.00218356935075221,"HALLMARK_HYPOXIA","kendall_tau","HN16","HN28",8.36461247173652e-05 "HALLMARK_SPERMATOGENESIS13",0.0516480519022084,0.0357384592301152,0.120058507970059,3.83902821570938,34.1890531401879,19.1183308918635,2.83664405871693e-06,1.42375162834665e-05,0.00413208910143325,5.29258583685938e-05,5.68250703797193e-05,1.8890797866363e-05,1.8890797866363e-05,3.90378570763101e-06,1.93518875364655e-05,0.000123522236501472,0,0,0,0.00297705002021242,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN16","HN28",0.000189005116644112 "HALLMARK_OXIDATIVE_PHOSPHORYLATION13",0.062625568139051,0.0413519927798638,0.145041376130694,3.9742348979766,22.4510087315022,17.778661683498,6.46427488811382e-06,2.20889762928089e-05,0.00534352422853333,0.000266388566177837,0.000244418085646594,4.97355997315339e-05,4.97355997315339e-05,1.33756376288311e-05,3.39149981801904e-05,7.06058550430377e-05,0,0,0,0.0046278247631295,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN16","HN28",0.000109976802027301 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION13",0.0474499459065953,0.0335881848265719,0.104390218008628,3.17950735398416,25.2699269316769,15.6376651629655,4.23054643479154e-06,1.46766100655566e-05,0.00434823602169295,7.36808774470053e-05,5.9042454140663e-05,3.07267631811659e-05,3.07267631811659e-05,4.9772798795195e-06,2.03997063091972e-05,0.00147525626013034,0,0,0,0.00303694495694343,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN16","HN28",0.00208021746032768 "HALLMARK_MYC_TARGETS_V213",0.0555108022606297,0.0362341935579065,0.132368762914643,4.19226158244029,32.3390498531684,21.4812851045998,6.10330512960847e-06,1.4939592976788e-05,0.00458725387420366,6.0765257896174e-05,3.59478309121426e-05,4.06041786905455e-05,4.06041786905455e-05,5.54837083323464e-06,1.99280493090188e-05,2.76187274794726e-05,0,0,0,0.00347203080207525,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN16","HN28",4.47377734378234e-05 "HALLMARK_E2F_TARGETS13",0.0606869887923041,0.0366073407193643,0.109420785783534,6.02168319408634,21.8900834583657,19.8391420329092,7.02347697069406e-06,8.86711215695736e-06,0.00398630018032403,0.000140604350922053,6.05820646995062e-05,9.98444435708987e-05,9.98444435708987e-05,4.85639220114466e-06,1.3370303651546e-05,1.72612502069569e-09,0,0,0,0.00349517414997011,"HALLMARK_E2F_TARGETS","kendall_tau","HN16","HN28",4.02762504828994e-09 "HALLMARK_IL6_JAK_STAT3_SIGNALING13",0.0303832080964805,0.0234080492368677,0.074025502727214,2.77197339942424,27.6836556398186,16.8567824305339,1.3465459025822e-06,4.88529639327405e-06,0.00249636581771507,1.7497747688033e-05,5.4133506590298e-05,9.37346993703505e-06,9.37346993703505e-06,2.38523966879544e-06,8.91677478081495e-06,0.00557175894884931,0,0,0,0.00219736182121465,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN16","HN28",0.00753148106189287 "HALLMARK_PROTEIN_SECRETION13",0.0515964206290374,0.033604514334617,0.117984829171865,3.60817498817282,26.5096123602603,18.2463213653548,5.34764436382762e-06,1.94168239937245e-05,0.00497639109772856,7.44130421061542e-05,2.58090954270724e-05,1.51516491065764e-05,1.51516491065764e-05,6.17159147760156e-06,2.12861024826518e-05,0.0003083584908119,0,0,0,0.00315560233435121,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN16","HN28",0.000459024791385815 "HALLMARK_UV_RESPONSE_DN13",0.0406298318270149,0.0257200286163701,0.0917290989860554,4.25529133512183,28.5024851248445,19.9753163836956,2.52202161977081e-06,9.65477961815881e-06,0.0034895273659809,3.72671148821616e-05,3.38356979814568e-05,1.34551773451645e-05,1.34551773451645e-05,3.11413332785912e-06,1.0819931133428e-05,2.08776991046378e-05,0,0,0,0.00239232620639332,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN16","HN28",3.41002418709084e-05 "HALLMARK_APOPTOSIS13",0.0417382243773198,0.026967788971368,0.0949514424831065,3.90483275911296,32.4674326861633,17.866481144452,2.60768344461307e-06,1.16004083982663e-05,0.00376936225943851,3.04243243427343e-05,3.05428345256462e-05,2.12096971392807e-05,2.12096971392807e-05,2.58622972373742e-06,1.43787460172948e-05,9.42905690448637e-05,0,0,0,0.00243468333313034,"HALLMARK_APOPTOSIS","kendall_tau","HN16","HN28",0.000145138362822984 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY13",0.0357281524484558,0.0262855079984657,0.0858739903603385,3.09661265585886,27.3300756402278,17.7456991421841,1.90591897197266e-06,7.29259409276332e-06,0.0030329050536962,3.04540477491606e-05,4.51391315021447e-05,3.00383277363403e-06,3.00383277363403e-06,3.26657363342641e-06,1.11755678013616e-05,0.00195745467216768,0,0,0,0.00232296891010939,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN16","HN28",0.00274043654103475 "HALLMARK_COMPLEMENT13",0.0341583323623498,0.0253900594532725,0.0787492246853839,2.618159430972,30.0503089620357,15.5133941603243,1.64919394511451e-06,9.4667528130563e-06,0.0033340586014902,2.17629264048095e-05,2.71879779816554e-05,9.17588753492201e-06,9.17588753492201e-06,2.10188403909167e-06,1.17305353969002e-05,0.00884054897695163,0,0,0,0.00218702505615996,"HALLMARK_COMPLEMENT","kendall_tau","HN16","HN28",0.0117341823892721 "HALLMARK_APICAL_JUNCTION13",0.038766205271832,0.0250232258855252,0.0898072723631901,4.16149577382077,28.3558395581895,18.6166903364693,1.95465209739998e-06,8.85128213344885e-06,0.00328723808551325,3.83448793888786e-05,2.00990104821906e-05,-2.7535572440238e-06,-2.7535572440238e-06,3.14007057462412e-06,1.20096388768298e-05,3.16169850298476e-05,0,0,0,0.0019750706630327,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN16","HN28",5.07945005397551e-05 "HALLMARK_GLYCOLYSIS13",0.0481756791191288,0.0281412606268594,0.0891490092234453,5.7225620198246,23.9402456253212,18.3119962236262,3.60136449004008e-06,8.55530475236943e-06,0.00348664154200134,3.83961849576182e-05,2.2952012610631e-05,3.32419514243202e-05,3.32419514243202e-05,2.82917501736012e-06,1.09993773450784e-05,1.04929520627906e-08,0,0,0,0.00219939384399895,"HALLMARK_GLYCOLYSIS","kendall_tau","HN16","HN28",2.30648815436293e-08 "HALLMARK_PI3K_AKT_MTOR_SIGNALING13",0.0361791997405679,0.0243160904136514,0.0901272550877498,4.09435695410762,32.0372460139754,23.0741951503877,2.06073476183068e-06,6.23436111215978e-06,0.00288012080892286,2.74978753860757e-05,2.61712130671266e-05,6.22626358949899e-06,6.22626358949899e-06,2.73557563778989e-06,8.03478409090559e-06,4.23341680662048e-05,0,0,0,0.00233865912865734,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN16","HN28",6.74267086591923e-05 "HALLMARK_G2M_CHECKPOINT13",0.0699030363083021,0.0395772766270376,0.109530726459505,6.80633639212086,18.8363292668969,18.82184975379,9.48428215342853e-06,1.02673655282113e-05,0.00444428258345932,0.000247726753787982,2.08517188129056e-05,0.000162519630022663,0.000162519630022663,4.32593437510726e-06,1.37131799475073e-05,1.00115471468598e-11,0,0,0,0.0041402257133264,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN16","HN28",2.79657468995419e-11 "HALLMARK_APICAL_SURFACE13",0.0390069805726537,0.0334734182436962,0.0801470764461985,1.31488751351914,23.1397666962886,10.4246685853842,2.65497302377326e-06,1.49555917136083e-05,0.00419649433901459,3.70411909665176e-05,6.0807543276027e-05,2.83800665774004e-05,2.83800665774004e-05,3.06091376012897e-06,1.99456050269087e-05,0.188547709811899,0,0,0,0.00273871810140422,"HALLMARK_APICAL_SURFACE","kendall_tau","HN16","HN28",0.217867610433461 "HALLMARK_XENOBIOTIC_METABOLISM13",0.044946988463444,0.0284225395269028,0.0910645291037807,4.122290852614,27.4084398626728,15.9252193420801,2.3694827411833e-06,1.35990680360182e-05,0.00399606691350402,2.5947923292283e-05,2.35142334732725e-05,1.02472406892122e-05,1.02472406892122e-05,2.73115500451382e-06,1.53724910612002e-05,3.75123145446299e-05,0,0,0,0.00204964683782264,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN16","HN28",5.99381547615282e-05 "HALLMARK_WNT_BETA_CATENIN_SIGNALING13",0.0368445282613217,0.0348460383558539,0.0984535010978024,0.487898364946789,27.6988371097603,14.9075349540433,3.58782712692719e-06,1.30903661319674e-05,0.00408389437411089,2.35974693362385e-05,5.89779048057824e-05,9.07752514016542e-06,9.07752514016542e-06,4.84726146598909e-06,1.81055780039994e-05,0.625621832706454,0,0,0,0.00350146682463917,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN16","HN28",0.662820968705216 "HALLMARK_KRAS_SIGNALING_DN13",0.058651630074657,0.0437108519277465,0.122040979672406,3.27156815900022,26.9654805708019,16.7644131778018,4.28470672392996e-06,1.64714599390335e-05,0.00455589361848622,5.08924974752037e-05,8.05572613494614e-05,2.73393529512632e-05,2.73393529512632e-05,5.42606847875234e-06,2.17313683673196e-05,0.00106952804524774,0,0,0,0.0032177338719945,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN16","HN28",0.00153012771436902 "HALLMARK_COAGULATION13",0.0471657337757762,0.0327961859481197,0.109619255606316,3.16293436040116,23.7064016146139,15.2747920898296,3.49012372434456e-06,1.70496934511494e-05,0.00453208750748416,7.93456778250753e-05,5.95413202420566e-05,-1.38534080315568e-05,-1.38534080315568e-05,6.84036949733989e-06,2.51948843274762e-05,0.00156187543287611,0,0,0,0.00266585262565049,"HALLMARK_COAGULATION","kendall_tau","HN16","HN28",0.00219971917252971 "HALLMARK_HEDGEHOG_SIGNALING13",0.0491392049777658,0.026923549907768,0.0992266367213323,5.9224154621872,18.6135587691988,20.3800188624422,4.6105989367447e-06,9.36025669110676e-06,0.00373776077723702,0.000150937698853618,2.3163404114547e-05,2.84782052603193e-06,2.84782052603193e-06,7.1410025021387e-06,1.24864865057946e-05,3.17246895420453e-09,0,0,0,0.00247547928627316,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN16","HN28",7.20236195008597e-09 "CELL_CYCLE13",0.047158913074406,0.0310071446169007,0.0902448740236442,4.37715417781793,22.4553202169046,15.528815660167,3.85257868045622e-06,9.66363856839999e-06,0.00367644083984174,6.51259831826474e-05,4.86951977238283e-05,4.21733575069177e-05,4.21733575069177e-05,3.58156999538093e-06,1.44519146238201e-05,1.20238923151383e-05,0,0,0,0.0025970580110623,"CELL_CYCLE","kendall_tau","HN16","HN28",2.00001377123093e-05 "PEMT13",0.0705500071133874,0.0458758314855876,0.154040057045897,3.92580224153906,24.5574672511073,17.4598535153016,9.53536583995352e-06,2.98674874667844e-05,0.00627716921125581,7.44971597996524e-05,0.000181286223295878,6.29719424372101e-05,6.29719424372101e-05,1.1458521747233e-05,3.82783322929451e-05,8.64411537122578e-05,0,0,0,0.00439852497959342,"PEMT","kendall_tau","HN16","HN28",0.00013358054765521 "EPI_DIFF113",0.0541046684145276,0.0438669623059867,0.135762780675182,1.69004170261706,29.1355450129115,14.5415928711387,4.39061368013162e-06,3.22046889774485e-05,0.0060494051490688,2.34678226935826e-05,0.000161504644839373,1.60668052310541e-05,1.60668052310541e-05,7.75511194744165e-06,3.98362733954438e-05,0.0910199766467594,0,0,0,0.0043136827924346,"EPI_DIFF1","kendall_tau","HN16","HN28",0.110806928091707 "EPI_DIFF213",0.0618331402556755,0.0392707563439271,0.133661833033183,4.52708582139189,29.0312515192657,19.6860941464932,7.03461685452143e-06,1.77042920184445e-05,0.00497382236041517,0.000119115751879027,3.9960767723779e-05,6.50602106426548e-05,6.50602106426548e-05,6.02159239214872e-06,2.28902007999081e-05,5.98026575215904e-06,0,0,0,0.00359836500529802,"EPI_DIFF2","kendall_tau","HN16","HN28",1.02343249641878e-05 "STRESS13",0.0540392788034752,0.0341771307466914,0.137991677208623,3.63754998631504,29.7747979566325,19.2736382214258,6.51922566062622e-06,2.31957521030005e-05,0.00545114462875704,7.2399579231771e-05,5.10922701197555e-05,1.65973966644506e-05,1.65973966644506e-05,7.85002637310831e-06,2.89127580658962e-05,0.000275243786542534,0,0,0,0.00370300281051179,"STRESS","kendall_tau","HN16","HN28",0.00041076991494165 "HYPOXIA13",0.0543127658965543,0.0379901554117582,0.125105116320703,3.27284459798322,26.3065784329708,15.7807451005479,4.8609247514585e-06,1.99120921433109e-05,0.00497724993292174,4.00223029360797e-05,0.000130784515911024,2.61409334035055e-05,2.61409334035055e-05,7.1417567582902e-06,3.03740715095604e-05,0.00106470998480201,0,0,0,0.00343125243552869,"HYPOXIA","kendall_tau","HN16","HN28",0.00152509006349229 "HALLMARK_PANCREAS_BETA_CELLS14",0.0666050356191201,0.0771979577949727,0.0785079803368641,-2.9025684878517,3.62489464160948,0.73650395770771,6.72167220847496e-06,6.49717421781423e-06,0.00363577315385451,7.35475622678549e-05,0.000525134294141074,8.72042175257791e-05,8.72042175257791e-05,1.06824649894406e-05,3.06378795004979e-06,0.00370116221948424,0.000289079277905557,0.461424059909487,0.000867237833716672,0.00461137759331178,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN16","HN5",0.00509668240060125 "HALLMARK_MYOGENESIS14",0.0476061393486547,0.0654073624567887,0.0625221810122718,-5.52073673685755,5.38228963466373,-2.15092927966226,3.7784766480423e-06,6.51846511175364e-06,0.0032088848156012,6.22482845195364e-05,0.000438709714293652,6.43066541657126e-05,6.43066541657126e-05,7.58020913937029e-06,1.69926030182586e-06,3.3758123851868e-08,7.3544302203743e-08,0.031481782076086,1.01274371555604e-07,0.00445326634302339,"HALLMARK_MYOGENESIS","kendall_tau","HN16","HN5",7.14020749097065e-08 "HALLMARK_IL2_STAT5_SIGNALING14",0.0392525605896687,0.0517924539022566,0.0501060378622142,-5.06982460227253,4.72548616370538,-1.48433640181055,2.37482431639835e-06,3.64306779660824e-06,0.00245313923636768,3.0876822290467e-05,0.000301889685103753,3.79895067463814e-05,3.79895067463814e-05,5.17527143176466e-06,1.19081728449628e-06,3.98182484984133e-07,2.2956546610331e-06,0.137719697726205,1.1945474549524e-06,0.00348219667635601,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN16","HN5",7.68904108934878e-07 "HALLMARK_ESTROGEN_RESPONSE_EARLY14",0.0438919749653701,0.0648329617331342,0.0614580522963778,-7.40104780372654,5.29904672367497,-2.20355795419788,2.54358086016867e-06,5.36227683191947e-06,0.00281173570807929,2.56396682026096e-05,0.000679666977017287,3.83415919689039e-05,3.83415919689039e-05,1.08888964982044e-05,2.24571525682858e-06,1.35003119794419e-13,1.16408845229898e-07,0.0275554469939667,4.05009359383257e-13,0.00480864323050922,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN16","HN5",4.47221602473906e-13 "HALLMARK_BILE_ACID_METABOLISM14",0.0458022264863311,0.0620953382147412,0.0602848636798605,-6.27428621200925,5.00923732608749,-1.23822077043807,3.51740645064396e-06,3.12600128117243e-06,0.00257748088873931,3.26534220505062e-05,0.000461656176431781,4.63052696830593e-05,4.63052696830593e-05,8.25895690870165e-06,2.03790632308505e-06,3.51241924434476e-10,5.46461536909959e-07,0.215634212046051,1.05372577330343e-09,0.00403259718417469,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN16","HN5",8.64143311997789e-10 "HALLMARK_MITOTIC_SPINDLE14",0.0712586271397228,0.0868388982451834,0.0857041989430017,-3.47697446362495,4.13089967656476,-0.415264181520218,9.62053501993632e-06,1.03586933251022e-05,0.00446981301007532,0.000181893578444729,0.000690956335402587,0.000184005387038811,0.000184005387038811,1.21286968536507e-05,7.36642367609369e-06,0.00050710611360949,3.6134626310691e-05,0.677948519140581,0.000108403878932073,0.00568626041503785,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN16","HN5",0.000741737300503433 "HALLMARK_INFLAMMATORY_RESPONSE14",0.0377023217422396,0.0567048611476995,0.0528580862835698,-6.45955208752509,5.29940764100147,-3.51893933125923,2.3397521512775e-06,6.21427940401712e-06,0.00292472760360595,2.69606882309491e-05,0.000498332626854829,3.68892005295856e-05,3.68892005295856e-05,8.07901573678044e-06,1.09500570986533e-06,1.05013331364034e-10,1.16178986653281e-07,0.000433275776953623,3.15039994092103e-10,0.00442983961896942,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN16","HN5",2.69641217650883e-10 "HALLMARK_ESTROGEN_RESPONSE_LATE14",0.0496023578657877,0.0690578628102066,0.0661947270512749,-6.42463222765416,5.07818862976607,-1.77838623452128,2.951635883009e-06,6.11876814022956e-06,0.00301171114538539,3.49489362577882e-05,0.000655800424973952,4.7147052622929e-05,4.7147052622929e-05,1.05757684874819e-05,2.4919803573793e-06,1.32188704426994e-10,3.810502833268e-07,0.0753404419421808,3.96566113280983e-10,0.00480759396366475,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN16","HN5",3.35029992254623e-10 "HALLMARK_ADIPOGENESIS14",0.0366311316354432,0.0564948200342657,0.0528717931117403,-7.84846823841764,5.28254039904094,-2.70025648681128,2.12561079217967e-06,4.17984410437868e-06,0.00251106648588968,2.35539072680475e-05,0.000588705147897738,3.35837485063756e-05,3.35837485063756e-05,9.3519577940695e-06,1.70025110607939e-06,4.21884749357559e-15,1.27404728544889e-07,0.00692860379200555,1.26565424807268e-14,0.00446616559408758,"HALLMARK_ADIPOGENESIS","kendall_tau","HN16","HN5",1.5952941004646e-14 "HALLMARK_P53_PATHWAY14",0.0493229325702962,0.0727310000931841,0.0691727715728104,-7.09015828092081,5.21096701154439,-1.988042037067,4.51084387945722e-06,6.28897451580594e-06,0.00328630771463403,5.03323576995385e-05,0.000878216698676642,6.95290735537733e-05,6.95290735537733e-05,1.44103313420385e-05,3.10343964608294e-06,1.33959510151271e-12,1.87858857136902e-07,0.046807040998472,4.01878530453814e-12,0.00552141893387187,"HALLMARK_P53_PATHWAY","kendall_tau","HN16","HN5",4.03939445994603e-12 "HALLMARK_HEME_METABOLISM14",0.0419389300627888,0.0592759591717066,0.0575001927865098,-6.64697359970191,5.11681319522444,-1.21475996341906,2.66807994821904e-06,4.03493537264672e-06,0.00258901821563035,2.77249805226438e-05,0.000555032000937588,3.89385744398261e-05,3.89385744398261e-05,9.14890984347077e-06,2.03693209397122e-06,2.99180680229938e-11,3.107411037373e-07,0.224457654934533,8.97542040689814e-11,0.00431981612113313,"HALLMARK_HEME_METABOLISM","kendall_tau","HN16","HN5",8.0327963458997e-11 "HALLMARK_CHOLESTEROL_HOMEOSTASIS14",0.0406353709074141,0.0651818153351582,0.0602999597545487,-7.96193404591413,5.54771489004729,-2.98716873770104,3.57192046936416e-06,5.83281501051664e-06,0.0030667141177294,3.74915800647434e-05,0.000764891955548429,5.41708140220616e-05,5.41708140220616e-05,1.24643918905043e-05,2.57085520433472e-06,1.77635683940025e-15,2.89427328770131e-08,0.00281574262560147,5.32907051820075e-15,0.00523014235150097,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN16","HN5",6.94018486091261e-15 "HALLMARK_NOTCH_SIGNALING14",0.03798435775946,0.0555105703155775,0.0518734699966772,-6.6663752543515,4.98297083829617,-2.92426320791832,2.58698557733443e-06,4.22490151981498e-06,0.00260995921369461,4.15383326341791e-05,0.000467716412063227,4.40864979124483e-05,4.40864979124483e-05,7.66912812567224e-06,1.44695485448144e-06,2.62199151279674e-11,6.26153902727467e-07,0.00345272660158757,7.86597453839022e-11,0.00419464647460838,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN16","HN5",7.08841843459532e-11 "HALLMARK_ALLOGRAFT_REJECTION14",0.0388726791268356,0.0463594283966109,0.0466470874357313,-3.29350244694695,4.11622424431459,0.225821752078176,2.49939148057949e-06,2.56799086294755e-06,0.00225108470376551,3.73624265909323e-05,0.000180690830543872,4.00302527515507e-05,4.00302527515507e-05,3.46727540170453e-06,1.52264869784414e-06,0.000989474803731571,3.8512961476167e-05,0.821340058323134,0.000115538884428501,0.00283843888853454,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN16","HN5",0.00142078433356328 "HALLMARK_INTERFERON_GAMMA_RESPONSE14",0.0332405920844584,0.0575941779952491,0.0527264520279722,-9.08684275670256,5.6059676287617,-3.45089691524006,1.81942981706913e-06,5.2634699967264e-06,0.00266137179172613,1.88942525749212e-05,0.000773551630135789,2.92718160205604e-05,2.92718160205604e-05,1.19819763734388e-05,1.8897030696347e-06,0,2.07094670301444e-08,0.000558726931897846,0,0.00508118467356064,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN16","HN5",0 "HALLMARK_ANDROGEN_RESPONSE14",0.0409881511289962,0.0549615558570782,0.0533244787585759,-6.0111892247628,4.89747818100917,-1.21269944905115,2.02634532091842e-06,3.27726071299114e-06,0.00230295593399213,2.42340498280099e-05,0.000381032235384758,3.21237583894582e-05,3.21237583894582e-05,6.24492905066819e-06,1.7223504805819e-06,1.84167281425118e-09,9.7074409177722e-07,0.22524475056597,5.52501844275355e-09,0.00363716763564811,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN16","HN5",4.28872718724632e-09 "HALLMARK_TNFA_SIGNALING_VIA_NFKB14",0.0432197203320425,0.0661883137987541,0.0620892564567635,-7.07376069332451,5.42268140845018,-2.94319391369065,3.18249682313687e-06,7.26059709165276e-06,0.00323157762010904,3.23258327875262e-05,0.000742471298233851,4.81174463954474e-05,4.81174463954474e-05,1.20086093599012e-05,1.83968065288012e-06,1.50790491204589e-12,5.87115804862037e-08,0.00324844874269559,4.52371473613766e-12,0.00522022434467535,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN16","HN5",4.52371473613766e-12 "HALLMARK_PEROXISOME14",0.040062802093352,0.0575408956291522,0.0554197265216297,-7.29914424942739,5.17873437234423,-1.35765626527486,2.81165981892086e-06,2.82216242884905e-06,0.00237356740956938,2.38699981287165e-05,0.000514627834037215,3.79030032290283e-05,3.79030032290283e-05,8.69348896037277e-06,2.34101771219118e-06,2.89546164822241e-13,2.2339628880097e-07,0.174572780376604,8.68638494466722e-13,0.00409299908002991,"HALLMARK_PEROXISOME","kendall_tau","HN16","HN5",9.30345054182938e-13 "HALLMARK_INTERFERON_ALPHA_RESPONSE14",0.0422965153078158,0.0781150713643364,0.0697614424806762,-9.20691939964052,5.6215383101394,-4.74678175595211,3.38354443073285e-06,1.1651631241234e-05,0.00387752184674269,2.97056212589441e-05,0.00153674657570064,5.26957005599531e-05,5.26957005599531e-05,2.37696776552498e-05,2.99707573770739e-06,0,1.89264515171317e-08,2.06678749070655e-06,0,0.00726796949909974,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN16","HN5",0 "HALLMARK_TGF_BETA_SIGNALING14",0.0372656624583279,0.0611446294352518,0.0560373201168692,-7.32131132629355,5.32459261681897,-3.90297076753388,2.90570695637353e-06,7.63212976520771e-06,0.0032462034319465,3.04935498810551e-05,0.000770195209131554,4.44060730271749e-05,4.44060730271749e-05,1.23288938638968e-05,1.61235468121704e-06,2.45581333047085e-13,1.01179539857554e-07,9.50191825570545e-05,7.36743999141254e-13,0.00532080619896945,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN16","HN5",7.95602335160803e-13 "HALLMARK_FATTY_ACID_METABOLISM14",0.0348902736746205,0.0570226495369786,0.052593477498061,-8.98251355443111,5.59128349927223,-3.43305508514056,2.03476470509329e-06,3.93623639481641e-06,0.00244356319744542,1.46498581554411e-05,0.000623717424824706,2.88508626563838e-05,2.88508626563838e-05,9.92491531830704e-06,1.56449906384647e-06,0,2.25397214226319e-08,0.000596820829742439,0,0.00457792920228639,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN16","HN5",0 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE14",0.0551920273248241,0.0826319874827337,0.0782715825678827,-8.04441170364456,5.31095092011283,-2.03088746520463,4.51645866706696e-06,7.0188624738375e-06,0.00339636881697269,4.97554732780967e-05,0.00116129322077225,6.68334664133746e-05,6.68334664133746e-05,1.87847089058053e-05,4.50979829317083e-06,8.88178419700125e-16,1.09054699493072e-07,0.0422664116182248,2.66453525910038e-15,0.00615892697748182,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN16","HN5",3.5527136788005e-15 "HALLMARK_MTORC1_SIGNALING14",0.0476355014509166,0.061613676705554,0.0606998836942755,-4.91234124987383,4.58087110961284,-0.512835647527436,4.06873493840804e-06,3.92826069551633e-06,0.00282789597296725,6.10696537493983e-05,0.000470852764586511,6.96323011498182e-05,6.96323011498182e-05,8.03357756584145e-06,3.07496727418017e-06,8.99952423472072e-07,4.63043163589916e-06,0.608066291660516,2.69985727041622e-06,0.00417551650971636,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN16","HN5",1.67459501582778e-06 "HALLMARK_UV_RESPONSE_UP14",0.0412643940728578,0.0611758968042069,0.0584842534438037,-7.34531194966063,5.25527504763789,-1.6621359688773,2.75227852461662e-06,4.49603344891963e-06,0.00269226892667435,3.47062275617683e-05,0.000666532226631593,4.53104800532361e-05,4.53104800532361e-05,1.06366377180609e-05,2.52241811425488e-06,2.05169214950729e-13,1.47803412620107e-07,0.0964855150480053,6.15507644852187e-13,0.00471748630411661,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN16","HN5",6.70219435505715e-13 "HALLMARK_ANGIOGENESIS14",0.0582638689278528,0.0828383335846022,0.0776669970069171,-5.55778910626672,4.61123916874278,-3.30379665613741,7.46828796600882e-06,1.19824882664085e-05,0.00441030341727384,9.84668025623059e-05,0.00103495715883337,0.000118867592030574,0.000118867592030574,1.76055003655569e-05,2.35007281254511e-06,2.73213209833756e-08,4.00275679224293e-06,0.000953849910348969,8.19639629501268e-08,0.00646749413579522,"HALLMARK_ANGIOGENESIS","kendall_tau","HN16","HN5",5.83119300843007e-08 "HALLMARK_MYC_TARGETS_V114",0.0690738818985687,0.0969650733463011,0.0937773070873934,-6.14950959215504,4.91663505865907,-1.04955277935555,1.04854037845168e-05,9.98549024413857e-06,0.00452447721053553,0.000126574587215685,0.00149082493763088,0.000166390046174484,0.000166390046174484,2.51451758132074e-05,9.12495747698805e-06,7.77228947868025e-10,8.80444626094601e-07,0.293923777107475,2.33168684360407e-09,0.00716571171985521,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN16","HN5",1.86916409548629e-09 "HALLMARK_DNA_REPAIR14",0.0546771694659019,0.0877431465966066,0.0820101799842183,-8.64059644818538,5.36238483827969,-2.22792738971805,5.63192774094414e-06,8.91259684834324e-06,0.00381372843675154,4.94976498352038e-05,0.00162800530019137,8.42499814689849e-05,8.42499814689849e-05,2.5881186479405e-05,6.52150573841679e-06,0,8.21303294262776e-08,0.0258853573704232,0,0.00720088729664703,"HALLMARK_DNA_REPAIR","kendall_tau","HN16","HN5",0 "HALLMARK_KRAS_SIGNALING_UP14",0.0463152704358734,0.0653632732002873,0.0623515641241437,-6.0611625261528,5.11204888687136,-2.20107685273005,3.14824017999967e-06,6.62789513970758e-06,0.00312668119892439,4.07263575666638e-05,0.000591680604768577,4.99198446517191e-05,4.99198446517191e-05,9.74051903828741e-06,1.77221457665706e-06,1.35141187129761e-09,3.18683324618263e-07,0.0277305836468682,4.05423561389284e-09,0.00474838828726547,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN16","HN5",3.17852072129199e-09 "HALLMARK_HYPOXIA14",0.0383701202188002,0.0532235578616738,0.0515100042994033,-6.14045491964067,4.99315938515184,-1.26526337180213,2.221174379618e-06,3.53013228631673e-06,0.00239818820486106,3.19889602010252e-05,0.000415956316079498,3.6473198963544e-05,3.6473198963544e-05,6.82519822928865e-06,1.73414428406943e-06,8.22854895332625e-10,5.93994980091495e-07,0.205776932096836,2.46856468599788e-09,0.003834907580652,"HALLMARK_HYPOXIA","kendall_tau","HN16","HN5",1.96682389616091e-09 "HALLMARK_SPERMATOGENESIS14",0.0516480519022084,0.0783677152669511,0.0737082280873702,-8.45917018140227,5.50109883097713,-2.69108983149399,2.83664405871693e-06,7.04050452976945e-06,0.00314279311894474,2.70267012390628e-05,0.00101947049613192,4.35240111603531e-05,4.35240111603531e-05,1.59812224100746e-05,2.89791870467319e-06,0,3.77431559339669e-08,0.00712190148552816,0,0.00580539922615401,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN16","HN5",0 "HALLMARK_OXIDATIVE_PHOSPHORYLATION14",0.062625568139051,0.106907470666565,0.0981222887379696,-10.0652868576253,5.53250150868016,-2.94365125837557,6.46427488811382e-06,1.27910394996577e-05,0.00438808778259637,7.05089549440582e-05,0.0026251667404993,9.89287922764891e-05,9.89287922764891e-05,4.10654988163465e-05,8.8069457170867e-06,0,3.15695727337584e-08,0.0032436527640014,0,0.00909579240731595,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN16","HN5",0 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION14",0.0474499459065953,0.0669159456259134,0.0639288834333534,-5.8052705612687,4.89448243516702,-2.01555729459594,4.23054643479154e-06,6.91313403065802e-06,0.00333821516164695,5.5537998003433e-05,0.000670305061320303,6.71254534446021e-05,6.71254534446021e-05,1.12356092257981e-05,2.09633323802813e-06,6.42621489355122e-09,9.85647790718858e-07,0.0438462891950795,1.92786446806537e-08,0.0050540532242031,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN16","HN5",1.42320691427801e-08 "HALLMARK_MYC_TARGETS_V214",0.0555108022606297,0.0865534287534992,0.080919245189151,-7.97264581633503,5.39724778060881,-2.37424818780356,6.10330512960847e-06,8.95714083484625e-06,0.00388077904092139,7.11011968566955e-05,0.00137901036417845,9.98410906323903e-05,9.98410906323903e-05,2.20621245024459e-05,5.53131413352366e-06,1.55431223447522e-15,6.7670904213557e-08,0.0175847261284892,4.66293670342566e-15,0.0068509770797388,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN16","HN5",6.13379593202301e-15 "HALLMARK_E2F_TARGETS14",0.0606869887923041,0.0770090188893841,0.0754939061269959,-4.29569226039353,4.37440322141103,-0.64405817085227,7.02347697069406e-06,7.31369155411933e-06,0.00378644536799534,0.000115279932381119,0.000659252765576055,0.000126543010613978,0.000126543010613978,1.13575478096448e-05,5.43400725701684e-06,1.74149030180981e-05,1.21765127389928e-05,0.519537713394841,3.65295382169784e-05,0.00518458789961033,"HALLMARK_E2F_TARGETS","kendall_tau","HN16","HN5",2.852357374552e-05 "HALLMARK_IL6_JAK_STAT3_SIGNALING14",0.0303832080964805,0.0438505148675229,0.0416557442297082,-5.8970698152361,4.98951753677218,-2.10850905373198,1.3465459025822e-06,3.76887024376819e-06,0.00226172857486268,1.70687275048845e-05,0.000312564703370393,2.21504589511218e-05,2.21504589511218e-05,5.00418216140594e-06,9.83496075421144e-07,3.70013331085772e-09,6.05302793665885e-07,0.0349869804533824,1.11003999325732e-08,0.00342033298502346,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN16","HN5",8.3359325164151e-09 "HALLMARK_PROTEIN_SECRETION14",0.0515964206290374,0.0808002451855555,0.0756104577188188,-7.84702770173799,5.25796842051942,-2.4729782469714,5.34764436382762e-06,8.40297166938518e-06,0.00370818230851893,5.66710949160502e-05,0.00128517270641786,8.10902828902792e-05,8.10902828902792e-05,2.07590443429003e-05,4.30411401299032e-06,4.21884749357559e-15,1.45655523642318e-07,0.0133992298620011,1.26565424807268e-14,0.00657578580247258,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN16","HN5",1.5952941004646e-14 "HALLMARK_UV_RESPONSE_DN14",0.0406298318270149,0.0636038919621009,0.059581500063947,-8.30400371907744,5.40882321411136,-2.72027593865935,2.52202161977081e-06,5.03218950276032e-06,0.00274849251818722,2.32754859195313e-05,0.000765508507672178,3.72471071341343e-05,3.72471071341343e-05,1.21769169086893e-05,2.08646657346035e-06,0,6.34402130827993e-08,0.00652274600983294,0,0.00504199956419952,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN16","HN5",0 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"HALLMARK_COMPLEMENT14",0.0341583323623498,0.0525110057109235,0.0494266400411278,-7.6475943171616,5.5561136278123,-2.70176731853504,1.64919394511451e-06,4.00983135030971e-06,0.00237887059240813,1.61370698798691e-05,0.00046704788778593,2.4774213689066e-05,2.4774213689066e-05,7.45161026760401e-06,1.20327430587488e-06,2.04281036531029e-14,2.75847338304658e-08,0.00689720114510584,6.12843109593086e-14,0.00405386828384146,"HALLMARK_COMPLEMENT","kendall_tau","HN16","HN5",7.2359788843521e-14 "HALLMARK_APICAL_JUNCTION14",0.038766205271832,0.0582602519608445,0.0549447257308193,-7.85190152324477,5.46488193100812,-2.65610512405993,1.95465209739998e-06,4.10922989403823e-06,0.00246249507439877,1.65156606091316e-05,0.000532142517869384,2.60111487294873e-05,2.60111487294873e-05,8.66427584556805e-06,1.45816848727746e-06,3.99680288865056e-15,4.63215015233942e-08,0.00790489680728235,1.19904086659517e-14,0.004271106307832,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN16","HN5",1.52111333237963e-14 "HALLMARK_GLYCOLYSIS14",0.0481756791191288,0.0608712876224109,0.0605487394974034,-4.59525382726596,4.49572355368665,-0.184044622684509,3.60136449004008e-06,3.93150843606003e-06,0.00274460797311749,5.04318856668438e-05,0.000437841541262103,5.98548098645867e-05,5.98548098645867e-05,7.47451915171311e-06,2.97144524378189e-06,4.32222799617854e-06,6.93337692414531e-06,0.853978448942497,1.29666839885356e-05,0.0039848443623211,"HALLMARK_GLYCOLYSIS","kendall_tau","HN16","HN5",7.4859206531752e-06 "HALLMARK_PI3K_AKT_MTOR_SIGNALING14",0.0361791997405679,0.0595589319469917,0.0552425729270379,-9.49829497898443,5.57712818748316,-2.71365454455819,2.06073476183068e-06,3.89808117381495e-06,0.00244106860527221,1.69156720685867e-05,0.000738655374103007,3.08858627683841e-05,3.08858627683841e-05,1.15836421336999e-05,2.43003192477444e-06,0,2.44521685122123e-08,0.00665455205136722,0,0.00485581205995414,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN16","HN5",0 "HALLMARK_G2M_CHECKPOINT14",0.0699030363083021,0.0825236312726,0.0821211533809472,-2.89818099505921,3.7952206400087,-0.151902628281145,9.48428215342853e-06,9.37878791000238e-06,0.00434316360081346,0.000175683910769229,0.000564184096301273,0.000179544659991502,0.000179544659991502,1.02641694734214e-05,6.92026461127619e-06,0.00375333917838905,0.000147512211293943,0.879263735283923,0.000442536633881829,0.00530755496160371,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN16","HN5",0.00516248757167897 "HALLMARK_APICAL_SURFACE14",0.0390069805726537,0.0562548587066589,0.0516951540424904,-5.58327894650615,4.86272585724945,-3.939552381574,2.65497302377326e-06,6.78819779436889e-06,0.00307297426252518,3.58332420994467e-05,0.000406018183129398,4.45762869510698e-05,4.45762869510698e-05,6.70829934707859e-06,1.23961397400809e-06,2.36025721189748e-08,1.15780150000688e-06,8.16337773907883e-05,7.08077163569243e-08,0.00423418623469228,"HALLMARK_APICAL_SURFACE","kendall_tau","HN16","HN5",5.05585151400989e-08 "HALLMARK_XENOBIOTIC_METABOLISM14",0.044946988463444,0.0641057617349525,0.0607940110474593,-7.1703706848987,5.23533187456153,-2.64033928584469,2.3694827411833e-06,4.66976051773683e-06,0.00265315722468913,2.02592311924379e-05,0.000555396554298579,3.34050379076816e-05,3.34050379076816e-05,9.06235086938043e-06,1.47324295247212e-06,7.47846229387505e-13,1.64688675585722e-07,0.00828230647082284,2.24353868816252e-12,0.00440870184765608,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN16","HN5",2.30227006743379e-12 "HALLMARK_WNT_BETA_CATENIN_SIGNALING14",0.0368445282613217,0.058516939113954,0.0542312240143934,-6.0561852569478,5.14012037656877,-3.06458666200047,3.58782712692719e-06,9.1182510028429e-06,0.00356455861640261,4.27765391381096e-05,0.000693205238682393,5.67119633582045e-05,5.67119633582045e-05,1.13416202504724e-05,1.85570245176229e-06,1.39387457132045e-09,2.74562512503351e-07,0.00217971013747786,4.18162371396136e-09,0.00525423841765266,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN16","HN5",3.27184929315939e-09 "HALLMARK_KRAS_SIGNALING_DN14",0.058651630074657,0.0818373358338507,0.0789875137744306,-6.64608543628837,5.39145368268813,-1.66381600317904,4.28470672392996e-06,7.78580391739811e-06,0.00347426404312166,5.70019114660026e-05,0.00086017561748283,6.74315311731902e-05,6.74315311731902e-05,1.41270330966624e-05,2.83376209690954e-06,3.00990343760077e-11,6.98899746964798e-08,0.0961492049046826,9.02971031280231e-11,0.00558374621520243,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN16","HN5",8.062975951295e-11 "HALLMARK_COAGULATION14",0.0471657337757762,0.0676891897901491,0.0646624873985168,-6.43523569177599,5.1340687425033,-2.13006937666859,3.49012372434456e-06,6.58107347569357e-06,0.00317351495979429,3.35023997235038e-05,0.000680312749349187,4.61792662194249e-05,4.61792662194249e-05,1.15142613401657e-05,1.91907263368474e-06,1.23281829189636e-10,2.83544453694162e-07,0.0331658861177855,3.69845487568909e-10,0.004965320072883,"HALLMARK_COAGULATION","kendall_tau","HN16","HN5",3.1448900461391e-10 "HALLMARK_HEDGEHOG_SIGNALING14",0.0491392049777658,0.0671964851069329,0.0660793558541769,-6.31077704978131,4.91116928152262,-0.505003593909329,4.6105989367447e-06,3.4766688608745e-06,0.00284381219450568,5.50100339625397e-05,0.000665753931307117,6.25557339074697e-05,6.25557339074697e-05,1.17977472888771e-05,4.79348104972277e-06,2.77637912660111e-10,9.05348841007125e-07,0.613556311748388,8.32913737980334e-10,0.00462383411374262,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN16","HN5",6.8737302165956e-10 "CELL_CYCLE14",0.047158913074406,0.0620674405749033,0.0594645636520768,-5.16685286765999,4.55196002914084,-1.86522802267718,3.85257868045622e-06,4.37305526359356e-06,0.00286803660089089,5.5795441976775e-05,0.000418214887715619,6.51817633685299e-05,6.51817633685299e-05,7.20823120462835e-06,1.84734725539997e-06,2.38068521118961e-07,5.31484346510958e-06,0.0621494492106942,7.14205563356884e-07,0.00412923444442335,"CELL_CYCLE","kendall_tau","HN16","HN5",4.68174884340968e-07 "PEMT14",0.0705500071133874,0.105093906043703,0.0992391435906256,-7.049572761196,5.16842286314628,-2.37038204744193,9.53536583995352e-06,1.4376013770484e-05,0.00488992633998074,0.000102855488106308,0.00187453386404113,0.000146441476209219,0.000146441476209219,3.07119280484825e-05,6.00073076757791e-06,1.79478654160903e-12,2.36077686288638e-07,0.0177697128388672,5.38435962482708e-12,0.00812456375199784,"PEMT","kendall_tau","HN16","HN5",5.34346575425878e-12 "EPI_DIFF114",0.0541046684145276,0.0925990798989442,0.0839040818103252,-8.1595570702534,5.81317479575585,-5.10684496027979,4.39061368013162e-06,1.77661595076965e-05,0.00470709817061723,3.39252822354301e-05,0.00167499345477415,6.55073909492663e-05,6.55073909492663e-05,2.61777796301705e-05,2.79890267688915e-06,4.44089209850063e-16,6.12989947690323e-09,3.27582307946273e-07,1.33226762955019e-15,0.00789524568876907,"EPI_DIFF1","kendall_tau","HN16","HN5",1.82604514260026e-15 "EPI_DIFF214",0.0618331402556755,0.0922882374171384,0.0867775081060765,-7.66603207108272,5.25172928526506,-2.26175478890486,7.03461685452143e-06,8.64798915638878e-06,0.00396012701954246,8.45763409757054e-05,0.00138402979542533,0.000114006994405056,0.000114006994405056,2.24600647880964e-05,5.83645418739688e-06,1.77635683940025e-14,1.50677812227329e-07,0.0237125575837942,5.32907051820075e-14,0.00688261409423405,"EPI_DIFF2","kendall_tau","HN16","HN5",6.36888915589846e-14 "STRESS14",0.0540392788034752,0.0876117851916326,0.0814632149169609,-7.87316354436775,5.36119455027932,-2.98677809058676,6.51922566062622e-06,1.15639186087062e-05,0.00425242804399233,6.05497075123074e-05,0.00160614378325208,9.36913805013604e-05,9.36913805013604e-05,2.60659460810293e-05,4.13781865533924e-06,3.5527136788005e-15,8.26734205539026e-08,0.00281934289343466,1.06581410364015e-14,0.00743923106666733,"STRESS","kendall_tau","HN16","HN5",1.35649067736019e-14 "HYPOXIA14",0.0543127658965543,0.0791745998181354,0.0754984343830856,-6.69851858306728,5.14319911365865,-1.97724085183174,4.8609247514585e-06,8.81462022237343e-06,0.00369804610217773,5.47475310110311e-05,0.00103958367056228,7.59823952426368e-05,7.59823952426368e-05,1.68674926014972e-05,3.35677366663605e-06,2.10542694389915e-11,2.70099088206521e-07,0.0480144119372687,6.31628083169744e-11,0.00604538122548329,"HYPOXIA","kendall_tau","HN16","HN5",5.75809787447767e-11 "HALLMARK_PANCREAS_BETA_CELLS15",0.0582487986743306,0.0480557469590371,0.0977719507131272,3.20440791109412,16.6519571858963,15.9763859828825,2.36345951447541e-06,7.65496427001669e-06,0.00316518937577076,0.000329303896145657,0.000181031752749148,-5.3691033953353e-05,-5.3691033953353e-05,5.5334257535981e-06,9.58364432687341e-06,0.001353405781644,0,0,0,0.00269308546811269,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN17","HN22",0.00191990976985928 "HALLMARK_MYOGENESIS15",0.0433837044668863,0.0420113457187662,0.0839533451571584,0.513180384193112,19.6272897210849,18.7524632216392,1.55713581383564e-06,5.49433243928768e-06,0.002655460083135,0.000167924601373638,0.000146278425953265,-7.23745443150688e-05,-7.23745443150688e-05,4.17249591625512e-06,4.90243685656528e-06,0.607825146068045,0,0,0,0.00250394520612093,"HALLMARK_MYOGENESIS","kendall_tau","HN17","HN22",0.645711266283668 "HALLMARK_IL2_STAT5_SIGNALING15",0.0359501037470673,0.0368007893047348,0.0667934535166282,-0.370846244789959,17.7442551578408,12.6786952753882,8.38412040759536e-07,4.32358195375476e-06,0.00227200219949592,0.000147540839345804,0.00013808733597122,-3.92280810055578e-05,-3.92280810055578e-05,2.92139516556979e-06,5.49604196609197e-06,0.710752055028786,0,0,0,0.00201598012841613,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN17","HN22",0.743633822699157 "HALLMARK_ESTROGEN_RESPONSE_EARLY15",0.0416806622224135,0.0417217049497595,0.0857149850346717,-0.0134579782066275,19.7626113776059,19.0757320654577,1.59085471790633e-06,7.60978419487775e-06,0.00303325549744562,0.000207534757544337,0.000181455367397598,-9.24105739327115e-05,-9.24105739327115e-05,4.86471111161538e-06,5.2187583561885e-06,0.989262411097255,0,0,0,0.00272797408473926,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN17","HN22",0.990104336553507 "HALLMARK_BILE_ACID_METABOLISM15",0.0500296841862191,0.0435580324663076,0.0802523323006516,2.63891937932885,18.4296325084935,16.0346871937473,1.23480953462695e-06,4.67939272334531e-06,0.00243191329162293,0.000120154453646614,9.35654346178125e-05,-1.68361881435946e-05,-1.68361881435946e-05,2.58925310387004e-06,5.13692345914728e-06,0.00831707574102336,0,0,0,0.00202168426955746,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN17","HN22",0.0110643451034428 "HALLMARK_MITOTIC_SPINDLE15",0.0844883216857984,0.0753491428084734,0.117197085503914,2.13979946091842,10.5402151012445,9.22661492426529,2.53585304958983e-06,1.56059687047878e-05,0.00425932174816339,0.00085097090948345,0.000483664677296249,-2.89661863148473e-05,-2.89661863148473e-05,9.53006711687172e-06,2.04713803236926e-05,0.0323709768097844,0,0,0,0.00325816660307537,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN17","HN22",0.0414235785944575 "HALLMARK_INFLAMMATORY_RESPONSE15",0.032999325922355,0.031602112600324,0.0638713498144342,0.735321636555464,19.9556397303561,19.2627966370968,9.02805063827062e-07,2.607723170317e-06,0.00187364036947971,9.66731889620208e-05,6.63227408474968e-05,-4.45682805226061e-05,-4.45682805226061e-05,2.29330966008158e-06,2.70632987636479e-06,0.462143634119165,0,0,0,0.00183118275845917,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN17","HN22",0.505093785988976 "HALLMARK_ESTROGEN_RESPONSE_LATE15",0.0483822696424001,0.0485605638218152,0.0905670829318479,-0.052515470259131,18.5852920442894,14.2715835427603,1.39549393727145e-06,1.00310686637637e-05,0.00338031989625763,0.000272748577288732,0.00022470409305823,-7.76900354191009e-05,-7.76900354191009e-05,5.0519718661247e-06,8.5634138638795e-06,0.958117968859586,0,0,0,0.0027362534570419,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN17","HN22",0.966335104098519 "HALLMARK_ADIPOGENESIS15",0.0399082285013679,0.0330938335475744,0.0668486169026385,3.36625804457061,16.2228875586225,16.4622528643975,9.26812444100388e-07,3.07107281222877e-06,0.00199947124418661,0.000173483397186322,8.47818793065711e-05,-4.06523100931837e-05,-4.06523100931837e-05,2.65772774944025e-06,4.10428466150476e-06,0.000761953939274251,0,0,0,0.0017156202040089,"HALLMARK_ADIPOGENESIS","kendall_tau","HN17","HN22",0.00110761165956307 "HALLMARK_P53_PATHWAY15",0.0504327851840949,0.0454389451888412,0.0998484445399905,1.65598826036486,19.2547140100771,17.3152564456163,1.82731275605754e-06,7.16668283262745e-06,0.0029989990978133,0.000435775344234215,0.000231757704959496,-0.000114767188593183,-0.000114767188593183,6.48650527887039e-06,9.77396545637602e-06,0.0977241962536244,0,0,0,0.0028727559038437,"HALLMARK_P53_PATHWAY","kendall_tau","HN17","HN22",0.118355978160929 "HALLMARK_HEME_METABOLISM15",0.0374555938021136,0.0378211023784354,0.0707238848942958,-0.16334108778174,20.3251147915778,16.2085801049456,1.13653138011851e-06,3.77077605255961e-06,0.0022152443279869,0.000113178330358575,9.54799827628597e-05,-2.45263004597274e-05,-2.45263004597274e-05,2.57913730431623e-06,4.02074091946078e-06,0.870249884917571,0,0,0,0.00215939104400923,"HALLMARK_HEME_METABOLISM","kendall_tau","HN17","HN22",0.892252715486542 "HALLMARK_CHOLESTEROL_HOMEOSTASIS15",0.0432496542085583,0.0424846473959409,0.095054788769535,0.280547055665396,22.5003839013648,20.7944721552048,1.89122721726703e-06,5.44442682290112e-06,0.00270844125654742,0.000256316300939372,0.000117209551482486,-0.000127726464131822,-0.000127726464131822,5.20109706009242e-06,6.29120118061121e-06,0.779057829061397,0,0,0,0.00281398484443298,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN17","HN22",0.808624895830717 "HALLMARK_NOTCH_SIGNALING15",0.0318445510106457,0.0303404303219374,0.0640691613888957,0.652767956633348,19.9470707747605,18.8565423819381,1.21138260932817e-06,3.99804513530041e-06,0.00228241708384523,9.57524873009923e-05,7.69509391913871e-05,-2.98378640743052e-05,-2.98378640743052e-05,2.50985928927075e-06,3.09945408504512e-06,0.513905884368797,0,0,0,0.00210084167714214,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN17","HN22",0.556470201081669 "HALLMARK_ALLOGRAFT_REJECTION15",0.035556316312462,0.0340806200565269,0.0611041545804925,0.89718732822553,17.3142897617551,17.4295510506502,7.30732681513445e-07,1.8746436659711e-06,0.00161411782329685,0.000100898354800623,7.38811227844263e-05,-3.46391186836202e-05,-3.46391186836202e-05,2.07720314837207e-06,2.30387511599998e-06,0.369618965789496,0,0,0,0.00163035026510085,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN17","HN22",0.408910539763356 "HALLMARK_INTERFERON_GAMMA_RESPONSE15",0.0324665004454995,0.0290458811082174,0.0618528057713901,1.82571087084739,20.2992489525434,18.2677045842565,8.30813010936255e-07,2.5794971410895e-06,0.00184670250772174,0.000109446590818007,5.14102348153907e-05,-3.31003458801703e-05,-3.31003458801703e-05,1.9957044404087e-06,3.12524776553671e-06,0.0678938248393945,0,0,0,0.0017193835248339,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN17","HN22",0.0843116557667666 "HALLMARK_ANDROGEN_RESPONSE15",0.0410608749370838,0.0374515414794577,0.0776933248965335,1.43714741510406,18.7832954778286,19.1049175953488,1.29212593886654e-06,4.91528865310397e-06,0.00249146836062,0.000204490785528175,0.000110775704486518,-7.10209422526745e-05,-7.10209422526745e-05,3.7035431650106e-06,4.33674124598079e-06,0.150676110938091,0,0,0,0.00222367002619893,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN17","HN22",0.177195106463195 "HALLMARK_TNFA_SIGNALING_VIA_NFKB15",0.0389103836396684,0.0380961279836012,0.0885039591898888,0.29632710395071,22.3625593916666,21.6668445566161,2.09933477549648e-06,5.35121916971442e-06,0.00272957028581623,0.000171709388906356,0.000124780596749438,-9.48730113750624e-05,-9.48730113750624e-05,4.81821859575878e-06,5.31258449974989e-06,0.766980288981684,0,0,0,0.00285785751506843,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN17","HN22",0.798202495435806 "HALLMARK_PEROXISOME15",0.0490163780672548,0.0377547296106296,0.0796802617694881,5.0283644800139,16.9241680033031,18.7287553735992,1.12473557455698e-06,3.7911824798885e-06,0.00221718696876143,0.000224113438749258,8.62394132110384e-05,-5.3971157171713e-05,-5.3971157171713e-05,3.18276400298937e-06,4.91117227575855e-06,4.94680933105229e-07,0,0,0,0.00182320738882389,"HALLMARK_PEROXISOME","kendall_tau","HN17","HN22",9.52119111835924e-07 "HALLMARK_INTERFERON_ALPHA_RESPONSE15",0.0408069614541672,0.0372582289083985,0.0791304496258269,1.45523622985697,20.4441079143803,18.6267437864996,1.45159689110995e-06,4.39515120262435e-06,0.00241800498215663,0.000151970453556132,0.000108686871834267,-4.85501446755429e-05,-4.85501446755429e-05,3.41393507659624e-06,4.95333520547935e-06,0.145603874097872,0,0,0,0.00232005114459208,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN17","HN22",0.171838471890523 "HALLMARK_TGF_BETA_SIGNALING15",0.0400391803308972,0.0323103764477756,0.0794496236967565,3.24891177462156,18.5494613827882,22.0198059976498,1.67629717856474e-06,3.8828206755302e-06,0.0023577781604924,0.000302509378680291,5.80377324521609e-05,-0.000109995591125517,-0.000109995591125517,4.41398419531834e-06,4.48287814173014e-06,0.00115847402562541,0,0,0,0.00217632978865345,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN17","HN22",0.00165335613365957 "HALLMARK_FATTY_ACID_METABOLISM15",0.0367795138446028,0.032447008842743,0.0683718510235814,2.01193317045615,18.7382803103323,18.7225392674056,1.09161165722507e-06,3.4455372688468e-06,0.00213005843254871,0.000143089132006582,6.89917372508836e-05,-5.2597529969852e-05,-5.2597529969852e-05,2.74252340327101e-06,3.58180037514334e-06,0.0442269822080288,0,0,0,0.00189232353380223,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN17","HN22",0.0561067217655252 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE15",0.0588164433529175,0.0517290058487894,0.087230606820943,2.11287258287238,13.7159589156493,11.859570090282,1.65395214475087e-06,9.49810345496811e-06,0.00333946935900286,0.00035027386781086,0.00015439545987446,-1.47471130643511e-05,-1.47471130643511e-05,4.19158183272375e-06,8.86103109686538e-06,0.0346116751008863,0,0,0,0.00242803392579479,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN17","HN22",0.0442427499115676 "HALLMARK_MTORC1_SIGNALING15",0.0507147656862187,0.0474205881995077,0.0899024675196712,1.18840914603652,16.193010240068,14.1892129439541,1.45076123677155e-06,6.13279047637927e-06,0.00275382492420103,0.000367594675468538,0.00025076721671902,-8.94805233102886e-05,-8.94805233102886e-05,5.75658443498215e-06,8.86377256847958e-06,0.234672254839976,0,0,0,0.00253334296042369,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN17","HN22",0.267676597179255 "HALLMARK_UV_RESPONSE_UP15",0.0404658449935616,0.0407477310721495,0.0743422252932098,-0.114415013685024,17.6933057603306,13.553822821842,9.81034291598975e-07,4.98886132111835e-06,0.00244333698304539,0.000205231670932803,0.000178403142678115,-3.82574627925711e-05,-3.82574627925711e-05,3.56586134059427e-06,6.04345392763943e-06,0.908908812951116,0,0,0,0.00226683248614616,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN17","HN22",0.927844413220931 "HALLMARK_ANGIOGENESIS15",0.0451974221883036,0.0434293491407863,0.0917642006297469,0.532800265357632,17.8729270591866,16.4183064685483,2.19401799862818e-06,8.71811740362774e-06,0.00330335214626838,0.000271449273911015,0.000251424925260136,-0.000128608743555227,-0.000128608743555227,6.68829991519411e-06,8.56690549431295e-06,0.594171850137265,0,0,0,0.00292550658299476,"HALLMARK_ANGIOGENESIS","kendall_tau","HN17","HN22",0.632922188189696 "HALLMARK_MYC_TARGETS_V115",0.0651825751978353,0.0713302600555415,0.100776879823181,-1.63346913206153,12.5712729233635,8.37382491878636,3.35724298020572e-06,1.07072596481042e-05,0.00375026700760225,0.000256954912265019,0.000503047976592277,3.6824788914494e-05,3.6824788914494e-05,7.91682707268572e-06,1.2265826372475e-05,0.102370367662442,0,0,0,0.00361736792885164,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN17","HN22",0.123474412688237 "HALLMARK_DNA_REPAIR15",0.0613165445128695,0.0568325963390769,0.0938714595465932,1.4755619147927,12.9705660959894,12.5512728354825,1.82212115411833e-06,7.31222805731788e-06,0.00302230858971023,0.00037185109168651,0.000279860226291109,-7.416123413521e-05,-7.416123413521e-05,6.19963330168952e-06,8.60842783611839e-06,0.140061535555388,0,0,0,0.00258194871090243,"HALLMARK_DNA_REPAIR","kendall_tau","HN17","HN22",0.166040691343887 "HALLMARK_KRAS_SIGNALING_UP15",0.0396944937481275,0.0422857685942802,0.0762708204489303,-1.00277617946096,20.341661237352,16.5383701444791,9.76963322821711e-07,5.6006142329224e-06,0.00256467884066292,0.000155476902603596,0.000127242114417527,-5.08030175316409e-05,-5.08030175316409e-05,3.1331610695157e-06,4.12270223940615e-06,0.315968864459481,0,0,0,0.00231766330184683,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN17","HN22",0.352876908456172 "HALLMARK_HYPOXIA15",0.0358540464133322,0.0358656907955244,0.0744127852145883,-0.00481155392940915,21.4546985861484,16.8083561277208,1.02304049770272e-06,4.73378368601892e-06,0.00239933828038516,0.00015764008092961,0.000109985381910161,-5.81627155016771e-05,-5.81627155016771e-05,3.12998723159055e-06,5.15935895802164e-06,0.996160950219266,0,0,0,0.00223712843002668,"HALLMARK_HYPOXIA","kendall_tau","HN17","HN22",0.996160950219266 "HALLMARK_SPERMATOGENESIS15",0.0565625181461193,0.0484391956441972,0.0821876510499807,3.12250636750623,13.7518301034562,14.1855193276943,1.04307278016937e-06,5.62493307005152e-06,0.00258224821622959,0.000274352704724234,0.000134968425319928,-2.99985755770737e-05,-2.99985755770737e-05,3.37225215863759e-06,5.56001161175116e-06,0.00179318226520153,0,0,0,0.00198881434264701,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN17","HN22",0.00251945321849104 "HALLMARK_OXIDATIVE_PHOSPHORYLATION15",0.0616551594818169,0.0562728269757935,0.095881023155094,1.65891831758355,14.1712258250867,16.1684579332958,3.38809391211939e-06,7.03857691010271e-06,0.00322903558701698,0.000229103259609349,0.000124118200856527,-5.01328412526956e-05,-5.01328412526956e-05,5.7330271082602e-06,5.9011285059517e-06,0.0971322529850627,0,0,0,0.00286059503736102,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN17","HN22",0.117760339701478 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION15",0.0395303444550745,0.0393644336194575,0.0923308348465014,0.0686598567424273,22.3364698271304,22.4841406305346,1.74540621629119e-06,3.99366423762949e-06,0.00239563570976905,0.000256441342558764,0.000173845465226733,-0.000124120389813554,-0.000124120389813554,5.48787702964913e-06,5.44942959722982e-06,0.945260372439044,0,0,0,0.00288831954438646,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN17","HN22",0.957473038749626 "HALLMARK_MYC_TARGETS_V215",0.0560690394030163,0.0540463132252193,0.0870555976886712,0.680780564636987,12.4390706151114,9.88108088529159,1.8004444533123e-06,6.92750611468053e-06,0.00295431050636063,0.000331275680489373,0.000383142301993231,-6.71726739349086e-06,-6.71726739349086e-06,6.1054147847435e-06,1.10599773156555e-05,0.496010349645928,0,0,0,0.0027902392896436,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN17","HN22",0.539600528384469 "HALLMARK_E2F_TARGETS15",0.0731041149555384,0.063621740375399,0.0990641384858459,2.91075115735781,10.2411675400359,10.2501188647885,1.98586058893158e-06,8.52679466606864e-06,0.00324232250940591,0.000407253380283277,0.000366701123654676,-1.98657822939128e-06,-1.98657822939128e-06,6.32556352493726e-06,1.18560685302706e-05,0.00360561051707764,0,0,0,0.00272399049843558,"HALLMARK_E2F_TARGETS","kendall_tau","HN17","HN22",0.00497092376094174 "HALLMARK_IL6_JAK_STAT3_SIGNALING15",0.0267726981832324,0.0269314635998066,0.0451519467109825,-0.0971297995736775,15.8815717855856,13.5523081599443,5.74648598622642e-07,1.99716914284304e-06,0.00160368879196236,6.08395581511195e-05,4.73148502607539e-05,-6.81916473262894e-06,-6.81916473262894e-06,1.23927122196778e-06,1.70756215253807e-06,0.922623316101442,0,0,0,0.00143297664011684,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN17","HN22",0.938585657210463 "HALLMARK_PROTEIN_SECRETION15",0.051950392987627,0.0456307143731712,0.0956776382801924,2.23490619235619,18.5515411953585,18.0301169653827,2.3263734023969e-06,5.56960087161897e-06,0.00280997762873939,0.00023714245842058,0.000183282714731874,-7.18238454640073e-05,-7.18238454640073e-05,5.45576985909247e-06,7.60473471568994e-06,0.0254235079472909,0,0,0,0.00275295404884228,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN17","HN22",0.0327112093501248 "HALLMARK_UV_RESPONSE_DN15",0.0352653140612522,0.0352100956537646,0.07249939726544,0.0223896236264197,20.1951276186251,18.4320221989384,1.25086471785348e-06,4.73152395225638e-06,0.00244589220328899,0.000131224912730671,0.000108059435207117,-6.12736443330957e-05,-6.12736443330957e-05,3.29928928968572e-06,3.99281891175329e-06,0.982137157425104,0,0,0,0.00227503111523036,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN17","HN22",0.983810304200956 "HALLMARK_APOPTOSIS15",0.0428782436782635,0.0385908379564059,0.0843628548257248,1.62392650187797,20.6232105674695,19.0304769459162,1.36416886710757e-06,5.50621069516156e-06,0.0026211408894352,0.000200913977900781,0.000126959837722879,-7.47815749333777e-05,-7.47815749333777e-05,3.94633182832557e-06,5.68496523047174e-06,0.104391495672613,0,0,0,0.00238091322386757,"HALLMARK_APOPTOSIS","kendall_tau","HN17","HN22",0.125783195605525 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY15",0.0305115351644373,0.0325616252866878,0.0621945439516316,-1.00732206530253,21.9032752759813,15.7178400185195,7.612976317555e-07,3.28069394881796e-06,0.00201047048736694,8.43075042412491e-05,8.39164535855579e-05,-2.23077219208172e-05,-2.23077219208172e-05,1.99235182890986e-06,3.45437405273866e-06,0.313780029544124,0,0,0,0.00197069214219507,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN17","HN22",0.351072015547237 "HALLMARK_COMPLEMENT15",0.0320263006590265,0.030843049723423,0.0628723498101198,0.586788054215128,20.8237752929373,18.0632826253551,8.43158315793043e-07,3.12306461555391e-06,0.00199153783075968,8.58107621528187e-05,6.04417523730229e-05,-3.98569969637494e-05,-3.98569969637494e-05,2.09421992857704e-06,3.0441375883541e-06,0.557346060707666,0,0,0,0.00181647076504039,"HALLMARK_COMPLEMENT","kendall_tau","HN17","HN22",0.596938950266134 "HALLMARK_APICAL_JUNCTION15",0.0342925301648706,0.0344037449746954,0.0664738768965786,-0.0485110587823994,20.948778475091,17.3830896631949,1.04753281516999e-06,4.10832660081842e-06,0.00227065176017557,8.93463088418416e-05,6.16875208673774e-05,-3.4916000499294e-05,-3.4916000499294e-05,2.25988598237339e-06,3.30367082650532e-06,0.961308951185545,0,0,0,0.00201631198308323,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN17","HN22",0.968722644896488 "HALLMARK_GLYCOLYSIS15",0.0496185977975972,0.0467165364182854,0.0885862791849947,0.971227336272346,18.2604495604569,13.0459386114509,1.09986141890955e-06,7.72849239191954e-06,0.0029712545853274,0.00031971494697244,0.000226241167191082,-3.99339233254905e-05,-3.99339233254905e-05,4.45392842593046e-06,1.02003011961618e-05,0.331435084022512,0,0,0,0.00251028503209779,"HALLMARK_GLYCOLYSIS","kendall_tau","HN17","HN22",0.368748967654185 "HALLMARK_PI3K_AKT_MTOR_SIGNALING15",0.0374506024202073,0.0346863386814961,0.0646955402207503,1.3423328839458,15.8657297034619,14.3393747216108,9.01598491064113e-07,3.23911072966883e-06,0.00203487326896123,0.0001740488128035,0.000109819709809723,-4.09998931731989e-05,-4.09998931731989e-05,2.84884224230597e-06,4.27974123712837e-06,0.179488085696307,0,0,0,0.00183035514707679,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN17","HN22",0.208988107701839 "HALLMARK_G2M_CHECKPOINT15",0.0842458798552031,0.0742944461661677,0.109708744895857,2.48911795714901,8.43620958514017,8.30675512000508,2.73670870944759e-06,1.31471028576815e-05,0.00398544998301686,0.000637302160200881,0.000493139062343745,-1.63413572446588e-05,-1.63413572446588e-05,9.01003016821505e-06,1.80758394181001e-05,0.0128060469839826,0,0,0,0.00312639540947291,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN17","HN22",0.0168267164839816 "HALLMARK_APICAL_SURFACE15",0.0395299181498633,0.035877267021045,0.0702666959537996,1.32409225409185,17.2145973614163,14.4792401996774,7.95009502097892e-07,6.71490711194871e-06,0.00274042270718344,0.000203227624973664,0.000150057715333811,-3.4336000749056e-05,-3.4336000749056e-05,3.08803394285609e-06,5.54102965058726e-06,0.18547240778141,0,0,0,0.00209396868584431,"HALLMARK_APICAL_SURFACE","kendall_tau","HN17","HN22",0.214680660975333 "HALLMARK_XENOBIOTIC_METABOLISM15",0.0394854349115014,0.0422634537163814,0.0773429958552631,-1.11342422860723,20.7666385193658,15.0111203650294,1.0266391035251e-06,5.09849952751831e-06,0.00247490174169469,0.000152440961461814,0.000132535171033984,-5.12327438254179e-05,-5.12327438254179e-05,3.22332529950345e-06,5.36111872145926e-06,0.265526274024785,0,0,0,0.00232906788237713,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN17","HN22",0.301408202947054 "HALLMARK_WNT_BETA_CATENIN_SIGNALING15",0.0330011081660574,0.0362668424128643,0.0743830865679605,-1.13898939315794,20.5896325256546,19.3686582936018,1.59311488644775e-06,6.52784107414752e-06,0.00284972910301931,0.000122807011673916,0.000151538201003026,-5.78152542775631e-05,-5.78152542775631e-05,3.93947856753547e-06,3.77276483081421e-06,0.254707578238014,0,0,0,0.0027054244329163,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN17","HN22",0.28968676209662 "HALLMARK_KRAS_SIGNALING_DN15",0.056252546393854,0.054607160153672,0.0958184143853335,0.555710277644053,18.1034406979089,16.5709467353901,1.68822761787827e-06,6.97852727309232e-06,0.00294393527289079,0.000183108717007252,0.000187156557238239,-7.10123958159821e-05,-7.10123958159821e-05,4.67660300929384e-06,6.0849617988191e-06,0.57840892947561,0,0,0,0.00259544389317748,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN17","HN22",0.617249456500288 "HALLMARK_COAGULATION15",0.040956776475856,0.0407437596429873,0.079372185854708,0.094265096794559,22.066431105947,17.961609025692,1.16507940706231e-06,3.84145204324344e-06,0.00223752797754704,8.97160058511582e-05,0.000119281283723585,-4.05418690139605e-05,-4.05418690139605e-05,2.93072641433799e-06,4.52512582064915e-06,0.924898575143407,0,0,0,0.00228730602285756,"HALLMARK_COAGULATION","kendall_tau","HN17","HN22",0.940087056498398 "HALLMARK_HEDGEHOG_SIGNALING15",0.043784028118017,0.045164386791606,0.0982574634131728,-0.458615260655094,21.7151409877404,18.0869484339123,2.33855264903435e-06,6.62058571830363e-06,0.00299318198032428,0.000211015839373392,0.000182392012589573,-0.000138773552609811,-0.000138773552609811,6.19280424267487e-06,8.51678355531524e-06,0.646510475822805,0,0,0,0.00308382888276605,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN17","HN22",0.681269103555213 "CELL_CYCLE15",0.061377518391058,0.0448368027231437,0.0896604908262662,7.45793198507736,15.030574556345,19.3156780311832,1.02996764441957e-06,3.78897496774541e-06,0.00219520901332082,0.00021952542789185,0.0001885147161317,-1.33176819662861e-05,-1.33176819662861e-05,3.44077994028265e-06,5.28511844232753e-06,8.79296635503124e-14,0,0,0,0.00199355761140038,"CELL_CYCLE","kendall_tau","HN17","HN22",2.96290212994749e-13 "PEMT15",0.0662761575411479,0.0597734070515726,0.160202524352257,1.44976199076842,23.5117960450215,23.8014774962674,5.81476184710602e-06,1.42039774073158e-05,0.00447423057680556,0.000790379736297156,0.000286614794803495,-0.000432344391461921,-0.000432344391461921,1.5858917722848e-05,1.77037487575842e-05,0.147124902196796,0,0,0,0.0048098173743762,"PEMT","kendall_tau","HN17","HN22",0.173365616215864 "EPI_DIFF115",0.0464511765904416,0.0533030921665019,0.116487304931155,-1.48161962028576,22.0792192700623,17.5549995225732,2.82577605145866e-06,1.84612582303584e-05,0.00461378741185775,0.000278948816236808,0.000502567988930972,-0.000170567993956588,-0.000170567993956588,9.96182674162257e-06,1.28543466307685e-05,0.138441535426126,0,0,0,0.00430619547110711,"EPI_DIFF1","kendall_tau","HN17","HN22",0.164451763294064 "EPI_DIFF215",0.0693842542585289,0.0587074275010466,0.11660603488411,2.71606499113418,14.8960429419799,13.8113856866088,2.50576621433529e-06,1.28469232228055e-05,0.003918250813455,0.000855289903364788,0.000445739199414468,-9.1261696202145e-05,-9.1261696202145e-05,9.94946373660179e-06,1.74736401548017e-05,0.00660629481849551,0,0,0,0.00336169477187004,"EPI_DIFF2","kendall_tau","HN17","HN22",0.00884852244481858 "STRESS15",0.0547433255313161,0.0473715758738033,0.120127724406137,1.94745844569606,20.5750889660485,20.9257039292963,3.39209645168668e-06,1.08365364877628e-05,0.00377208601962489,0.000550340967878206,0.000249298053594936,-0.000234625631507506,-0.000234625631507506,9.99868502977195e-06,1.1988690232566e-05,0.0514797969771779,0,0,0,0.00358208423780651,"STRESS","kendall_tau","HN17","HN22",0.0648877183763785 "HYPOXIA15",0.0544872438607883,0.0503883995450113,0.115249127330323,1.24082711054328,22.4881737225364,20.9491301313542,2.34977903528932e-06,8.46211898902023e-06,0.00328814507348893,0.000486195456454421,0.00018687425515531,-0.000149081979261509,-0.000149081979261509,7.20052478644305e-06,9.48587244920509e-06,0.214669623862604,0,0,0,0.0033253910114782,"HYPOXIA","kendall_tau","HN17","HN22",0.246294124548704 "HALLMARK_PANCREAS_BETA_CELLS16",0.0582487986743306,0.0469384018164506,0.108986258986259,2.3374669659843,25.3269037225202,12.417011221589,2.36345951447541e-06,2.09499533501288e-05,0.00482839651070666,7.11056383316793e-05,5.69395953926386e-05,4.49453030920786e-06,4.49453030920786e-06,3.91322260985305e-06,2.48700509298106e-05,0.0194149166562674,0,0,0,0.00560455010558302,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN17","HN28",0.0252565729953213 "HALLMARK_MYOGENESIS16",0.0433837044668863,0.0386590268415247,0.116205032925158,1.24929748340697,39.9903674149777,22.3644040176019,1.55713581383564e-06,1.26453864279999e-05,0.0037686233881665,0.000101250295379272,1.49174000462111e-05,-8.15218897525522e-05,-8.15218897525522e-05,3.21593803447263e-06,1.19227609271036e-05,0.211556288050358,0,0,0,0.0065314720255703,"HALLMARK_MYOGENESIS","kendall_tau","HN17","HN28",0.242959174557833 "HALLMARK_IL2_STAT5_SIGNALING16",0.0359501037470673,0.0253116190709646,0.0856219586476358,3.65093761275069,35.89088839788,20.7762216094392,8.38412040759536e-07,7.55242920943943e-06,0.00289669488386315,4.65976535151654e-05,2.03915424095103e-05,-2.79177318816856e-05,-2.79177318816856e-05,1.81536849440748e-06,8.32656178482608e-06,0.000261284708146015,0,0,0,0.00449439918312313,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN17","HN28",0.000390929792340602 "HALLMARK_ESTROGEN_RESPONSE_EARLY16",0.0416806622224135,0.0298062875352372,0.111234169740053,3.58772193748454,36.804479052545,27.2380031895327,1.59085471790633e-06,9.26342798990488e-06,0.00329458384440451,8.8103977423877e-05,3.37882252323986e-05,-6.5129287089215e-05,-6.5129287089215e-05,3.4713854262361e-06,8.83708208030608e-06,0.00033357975866144,0,0,0,0.00627985640928813,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN17","HN28",0.000495941588098424 "HALLMARK_BILE_ACID_METABOLISM16",0.0500296841862191,0.0274662946919044,0.109093982722031,7.44231489674409,37.2915974404239,25.2037781459525,1.23480953462695e-06,7.85682180237724e-06,0.00301523321436405,8.05632687105404e-05,1.60424303087391e-05,-4.44148275842013e-05,-4.44148275842013e-05,2.40858098642481e-06,1.03892321097639e-05,9.9031893796564e-14,0,0,0,0.00525222265976473,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN17","HN28",3.32747163156455e-13 "HALLMARK_MITOTIC_SPINDLE16",0.0844883216857984,0.0398244882951342,0.130576663806839,11.2663321706607,30.7099848488577,27.5498514889143,2.53585304958983e-06,1.30803230487055e-05,0.00395173077249645,0.000215919240623717,2.5853441004333e-05,0.000137646503295246,0.000137646503295246,2.15228304638082e-06,1.07511449624502e-05,0,0,0,0,0.00542548135388982,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN17","HN28",0 "HALLMARK_INFLAMMATORY_RESPONSE16",0.032999325922355,0.0292877915074263,0.0951165451962118,1.00675147667464,40.1265428641352,18.7449857362554,9.02805063827062e-07,1.25885398267357e-05,0.00367305661412437,3.79648498522699e-05,3.6969798105968e-05,-3.10904742432776e-05,-3.10904742432776e-05,2.29640668945973e-06,1.22327814978992e-05,0.314054217989535,0,0,0,0.00551272697569535,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN17","HN28",0.351072015547237 "HALLMARK_ESTROGEN_RESPONSE_LATE16",0.0483822696424001,0.0337243534746905,0.109677871991146,4.31440242728071,39.1979572999583,23.1795249852985,1.39549393727145e-06,1.00470932534805e-05,0.00338268934292701,4.11162572597334e-05,2.57880035838993e-05,-1.61892622689295e-05,-1.61892622689295e-05,2.34529783545624e-06,1.06370933956827e-05,1.60035195595487e-05,0,0,0,0.00563581793842376,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN17","HN28",2.62851103380297e-05 "HALLMARK_ADIPOGENESIS16",0.0399082285013679,0.0239024390243902,0.093205279041516,5.28197939715643,36.1547890133802,24.8726059821307,9.26812444100388e-07,8.15568455239219e-06,0.00301371813487801,4.82862661514271e-05,3.17262899203804e-05,-1.86555974288371e-05,-1.86555974288371e-05,2.07307486570152e-06,7.66353444883745e-06,1.27795572790745e-07,0,0,0,0.00479017346793146,"HALLMARK_ADIPOGENESIS","kendall_tau","HN17","HN28",2.58226105845217e-07 "HALLMARK_P53_PATHWAY16",0.0504327851840949,0.0312095845079054,0.124592413285942,4.80283608686779,39.1843486880009,25.1013621535212,1.82731275605754e-06,1.40924422171878e-05,0.00398995676333031,0.000113314005639385,2.97093626473663e-05,-4.83914379969946e-05,-4.83914379969946e-05,3.48187001668968e-06,1.37401077710851e-05,1.56433940445844e-06,0,0,0,0.00667009041909376,"HALLMARK_P53_PATHWAY","kendall_tau","HN17","HN28",2.82590344031201e-06 "HALLMARK_HEME_METABOLISM16",0.0374555938021136,0.0262893736977571,0.0937188919467998,3.56398691333413,41.208648425563,23.2161923918614,1.13653138011851e-06,8.57959558686389e-06,0.00311707025377716,3.92485580427582e-05,1.31423729492139e-05,-1.55188201818928e-05,-1.55188201818928e-05,1.76411899747432e-06,8.33564171056844e-06,0.000365264173238788,0,0,0,0.00516322901524009,"HALLMARK_HEME_METABOLISM","kendall_tau","HN17","HN28",0.000540315305319264 "HALLMARK_CHOLESTEROL_HOMEOSTASIS16",0.0432496542085583,0.0266793689780659,0.126333051759046,5.0202728627745,42.6129354722918,31.7624406556998,1.89122721726703e-06,8.90322310898626e-06,0.00328549088056158,7.29929502116186e-05,3.13344363628912e-05,-6.80414761947178e-05,-6.80414761947178e-05,3.70141768691701e-06,9.74371367376512e-06,5.15981313009561e-07,0,0,0,0.00733035396142578,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN17","HN28",9.91493503430138e-07 "HALLMARK_NOTCH_SIGNALING16",0.0318445510106457,0.0241787962234461,0.0644821543523353,2.27531638300898,20.165251048274,15.1093266552954,1.21138260932817e-06,1.00394118103095e-05,0.00335422038924661,4.00741750082598e-05,6.95791767634747e-05,4.21003395568741e-05,4.21003395568741e-05,2.51956544894073e-06,7.01528411518466e-06,0.0228869573466937,0,0,0,0.00397803428479508,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN17","HN28",0.0296748201099358 "HALLMARK_ALLOGRAFT_REJECTION16",0.035556316312462,0.023572820941242,0.0710471938242584,4.64113147483021,30.3580634836628,20.8123163515652,7.30732681513445e-07,5.83609580121254e-06,0.002562582385549,3.908858567941e-05,5.93655298067059e-06,-2.25028090684973e-05,-2.25028090684973e-05,1.26673823832872e-06,5.10328526009862e-06,3.46506557913351e-06,0,0,0,0.00343368915037506,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN17","HN28",6.05485456324072e-06 "HALLMARK_INTERFERON_GAMMA_RESPONSE16",0.0324665004454995,0.0241889664686802,0.104054497489746,2.70056946377233,45.6032453675488,25.1857320127936,8.30813010936255e-07,8.46406702391754e-06,0.00304875056947166,4.89465599241862e-05,4.05610181975352e-05,-3.26571745620377e-05,-3.26571745620377e-05,2.36427358671249e-06,9.9556375552384e-06,0.00692208803671113,0,0,0,0.00612698438392525,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN17","HN28",0.00923992682312405 "HALLMARK_ANDROGEN_RESPONSE16",0.0410608749370838,0.0239950726779995,0.0860072789984098,5.88228986759974,27.2150808247092,26.2970075432852,1.29212593886654e-06,7.0249369991801e-06,0.00288393185391865,9.79386064573172e-05,2.98360765129393e-05,-2.56507511769508e-05,-2.56507511769508e-05,2.62753697412448e-06,5.46085671283252e-06,4.04628885952718e-09,0,0,0,0.00446963941768097,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN17","HN28",9.09834741645117e-09 "HALLMARK_TNFA_SIGNALING_VIA_NFKB16",0.0389103836396684,0.0342310332148548,0.117520639041475,1.07329011989637,36.9619340281209,23.3318754473768,2.09933477549648e-06,1.68086850490115e-05,0.00434833529347818,0.000101104327393587,3.72025464739616e-05,-9.15868077546343e-05,-9.15868077546343e-05,4.42323383176436e-06,1.26433119569686e-05,0.283140966764672,0,0,0,0.00720477682436359,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN17","HN28",0.31924619071453 "HALLMARK_PEROXISOME16",0.0490163780672548,0.0219372901895781,0.0935521658056516,10.5998582648344,32.7754201139491,30.6634555178755,1.12473557455698e-06,5.30157815211407e-06,0.00253501750026919,6.27283296950089e-05,1.05267176797319e-05,-1.44220025463373e-05,-1.44220025463373e-05,1.74638278589521e-06,5.35461741304141e-06,0,0,0,0,0.00422391982036509,"HALLMARK_PEROXISOME","kendall_tau","HN17","HN28",0 "HALLMARK_INTERFERON_ALPHA_RESPONSE16",0.0408069614541672,0.0345020673954166,0.134755222513228,1.46265784041427,43.2233583118623,23.5453634529671,1.45159689110995e-06,1.70294466087196e-05,0.00429895842034202,6.28393764347916e-05,9.72865815539216e-05,-5.02812783733072e-05,-5.02812783733072e-05,4.6243327373659e-06,1.80294780703452e-05,0.143561027754927,0,0,0,0.00812224079941166,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN17","HN28",0.169846849738223 "HALLMARK_TGF_BETA_SIGNALING16",0.0400391803308972,0.0321453529000699,0.0989345311787404,1.89209986104286,31.6891907919532,20.2800253561646,1.67629717856474e-06,1.5629228657156e-05,0.00415999108601458,0.00010245227445092,3.61944903018805e-05,-3.99784508327205e-05,-3.99784508327205e-05,3.35413834550299e-06,1.07461401825702e-05,0.0584776768439208,0,0,0,0.00568368298545141,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN17","HN28",0.0732372182837602 "HALLMARK_FATTY_ACID_METABOLISM16",0.0367795138446028,0.0245431376751887,0.0930001497503852,4.17526268277128,40.6460987054681,26.2400189198191,1.09161165722507e-06,7.39729793394906e-06,0.00291357333718822,2.11981485366951e-05,1.79577920468039e-05,-1.80945209083444e-05,-1.80945209083444e-05,1.8131709251052e-06,6.70624521341738e-06,2.97642399744724e-05,0,0,0,0.00512078751875371,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN17","HN28",4.79974608886283e-05 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE16",0.0588164433529175,0.031972172520953,0.122705281699184,6.21730117408447,33.8589844060091,24.8434340171784,1.65395214475087e-06,1.68883444064149e-05,0.00430607670056697,0.000153242203584347,4.2360923609118e-05,-2.54852097612895e-05,-2.54852097612895e-05,3.46042735087198e-06,1.32385411600587e-05,5.0577830812415e-10,0,0,0,0.00585634354072491,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN17","HN28",1.23401512521577e-09 "HALLMARK_MTORC1_SIGNALING16",0.0507147656862187,0.0270704743228337,0.109507199708818,7.5529574973894,33.7768932026497,27.3105865961051,1.45076123677155e-06,8.24906834099525e-06,0.00311445494071865,0.000134113172873538,1.93357475351957e-05,-4.95790752136384e-05,-4.95790752136384e-05,2.92972687679124e-06,9.01128029993217e-06,4.2632564145606e-14,0,0,0,0.00535450362379303,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN17","HN28",1.46168791356363e-13 "HALLMARK_UV_RESPONSE_UP16",0.0404658449935616,0.0291982997333115,0.0942229389236041,3.82553741232816,36.3259460742727,23.2866586791912,9.81034291598975e-07,7.59405024111176e-06,0.00292832452653573,3.18931512059938e-05,4.18639558503048e-05,7.2473400641827e-07,7.2473400641827e-07,2.08996764363103e-06,7.69725157686831e-06,0.00013048711492436,0,0,0,0.00494869743176221,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN17","HN28",0.000199289411884478 "HALLMARK_ANGIOGENESIS16",0.0451974221883036,0.0353735965931088,0.1187099215148,1.83485017649662,32.8530529350651,19.6911716678912,2.19401799862818e-06,2.63715183083295e-05,0.00534467363895661,8.10143822906582e-05,6.86660660895247e-05,-6.53915413445713e-05,-6.53915413445713e-05,4.90692297009676e-06,1.78112366551088e-05,0.066527891660934,0,0,0,0.00690675875495288,"HALLMARK_ANGIOGENESIS","kendall_tau","HN17","HN28",0.0827902651780512 "HALLMARK_MYC_TARGETS_V116",0.0651825751978353,0.0414086941234876,0.144077639573411,5.47056798876172,42.0781834342061,24.58521750014,3.35724298020572e-06,1.54285546639395e-05,0.00433425860374589,6.1359307776742e-05,2.34235276854282e-05,5.76672642896622e-05,5.76672642896622e-05,3.41548868689701e-06,1.73393419339403e-05,4.48595571800325e-08,0,0,0,0.00774138475154,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN17","HN28",9.40371466019933e-08 "HALLMARK_DNA_REPAIR16",0.0613165445128695,0.0348584342486781,0.13582363015567,7.24907218607344,37.1388081418207,25.7018514226194,1.82212115411833e-06,1.13993686020456e-05,0.00363613665257013,4.37053913375958e-05,9.03525728987997e-05,1.92662306797656e-05,1.92662306797656e-05,3.92475295529821e-06,1.53317282626409e-05,4.19664303308309e-13,0,0,0,0.00674732497826028,"HALLMARK_DNA_REPAIR","kendall_tau","HN17","HN28",1.32668070078111e-12 "HALLMARK_KRAS_SIGNALING_UP16",0.0396944937481275,0.0337291285201568,0.0966659617452384,1.69264225380574,30.3000818153723,22.5801927132103,9.76963322821711e-07,1.13436694209851e-05,0.00351007588861079,6.73115468169672e-05,7.54960490785099e-05,-3.40727419517587e-05,-3.40727419517587e-05,3.4353076905595e-06,7.66880973685327e-06,0.0905235831138758,0,0,0,0.00520524581222829,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN17","HN28",0.110316822530485 "HALLMARK_HYPOXIA16",0.0358540464133322,0.0261233607059689,0.0930190847066077,3.44299102385613,36.5562364218059,23.3261797473176,1.02304049770272e-06,6.86453746230574e-06,0.00280848321341048,5.78650319076873e-05,3.36659708465269e-05,-2.68803869272476e-05,-2.68803869272476e-05,2.34533319124578e-06,8.12449954642713e-06,0.000575318408839953,0,0,0,0.00516863324583946,"HALLMARK_HYPOXIA","kendall_tau","HN17","HN28",0.000840465153783584 "HALLMARK_SPERMATOGENESIS16",0.0565625181461193,0.0357384592301152,0.124777782156123,5.30980900106159,45.7314037383401,22.4022885639324,1.04307278016937e-06,1.42375162834665e-05,0.00390903940420608,6.31267257563111e-05,3.50963455872724e-05,-2.85832999956034e-06,-2.85832999956034e-06,2.12502074171679e-06,1.56971566063785e-05,1.09740178944051e-07,0,0,0,0.00590088367047302,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN17","HN28",2.22891969668746e-07 "HALLMARK_OXIDATIVE_PHOSPHORYLATION16",0.0616551594818169,0.0413519927798638,0.142561825904816,4.01456397122106,34.8330826698527,20.6469958368569,3.38809391211939e-06,2.20889762928089e-05,0.00504748157053875,9.43604268027337e-05,0.000120253738093861,0.000108251160165614,0.000108251160165614,5.29491732695498e-06,2.39287775652474e-05,5.95557898168675e-05,0,0,0,0.0080421258801284,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN17","HN28",9.31351181178672e-05 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION16",0.0395303444550745,0.0335881848265719,0.113193537903858,1.46188359140764,36.8915097679294,24.1983229968587,1.74540621629119e-06,1.46766100655566e-05,0.00405240870123533,7.61264450426843e-05,4.03414568950679e-05,-7.64765014534879e-05,-7.64765014534879e-05,3.88701828284658e-06,1.07221614131209e-05,0.143773112171824,0,0,0,0.00670038284050743,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN17","HN28",0.169926813983984 "HALLMARK_MYC_TARGETS_V216",0.0560690394030163,0.0362341935579065,0.134312135564847,4.83345081165572,42.3707942450983,22.6987494628941,1.8004444533123e-06,1.4939592976788e-05,0.00409145908327339,5.99101937797039e-05,6.07001633409279e-05,1.25768952612976e-05,1.25768952612976e-05,3.31003506858364e-06,1.8569763906687e-05,1.34186445821527e-06,0,0,0,0.00703363321645479,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN17","HN28",2.45417201067054e-06 "HALLMARK_E2F_TARGETS16",0.0731041149555384,0.0366073407193643,0.113427631486886,11.0277897520829,27.0389357937222,24.4725535510734,1.98586058893158e-06,8.86711215695736e-06,0.00329438503303559,0.000105490180062794,4.87432558535887e-05,0.000113055791290052,0.000113055791290052,2.12401447235289e-06,9.75356346828834e-06,0,0,0,0,0.00482684728570073,"HALLMARK_E2F_TARGETS","kendall_tau","HN17","HN28",0 "HALLMARK_IL6_JAK_STAT3_SIGNALING16",0.0267726981832324,0.0234080492368677,0.0776683355154613,1.42693605302757,37.6299329895263,19.9950681704326,5.74648598622642e-07,4.88529639327405e-06,0.00233665251843245,2.05484997701502e-05,3.81294317078323e-05,-1.34009874849582e-05,-1.34009874849582e-05,1.72933913089862e-06,7.26407805758734e-06,0.153598327654678,0,0,0,0.00451439087340706,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN17","HN28",0.180451182139762 "HALLMARK_PROTEIN_SECRETION16",0.051950392987627,0.033604514334617,0.115186792507877,3.92536830369163,37.2366785241787,19.8030928730333,2.3263734023969e-06,1.94168239937245e-05,0.00466296015382089,5.39459767910679e-05,1.601147044159e-05,7.95206815156543e-06,7.95206815156543e-06,2.78398102377914e-06,1.68717102650949e-05,8.65971380321628e-05,0,0,0,0.0062636178347373,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN17","HN28",0.000133645976805543 "HALLMARK_UV_RESPONSE_DN16",0.0352653140612522,0.0257200286163701,0.102317840552319,2.87727374808967,38.7557529715259,28.6669596968069,1.25086471785348e-06,9.65477961815881e-06,0.00330236950325252,6.96414375078187e-05,3.0580361721393e-05,-5.65612688555968e-05,-5.65612688555968e-05,2.89335299562126e-06,7.03952725973155e-06,0.00401127446906901,0,0,0,0.00596281451197597,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN17","HN28",0.00549157016952871 "HALLMARK_APOPTOSIS16",0.0428782436782635,0.026967788971368,0.108454977551611,4.40184667083758,39.5635668322806,25.3297269673638,1.36416886710757e-06,1.16004083982663e-05,0.0036006356751793,7.308361934945e-05,2.14432335187611e-05,-4.44408016602345e-05,-4.44408016602345e-05,2.64731645962768e-06,1.02494590769139e-05,1.07333400451992e-05,0,0,0,0.00586300348353061,"HALLMARK_APOPTOSIS","kendall_tau","HN17","HN28",1.79550610144442e-05 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY16",0.0305115351644373,0.0262855079984657,0.0787179687035286,1.47995944403569,35.8885485101071,18.6965172003987,7.612976317555e-07,7.29259409276332e-06,0.00283793793528308,1.61970856016715e-05,4.49110102362232e-05,1.66249017225341e-05,1.66249017225341e-05,1.7042562426296e-06,7.7646437209198e-06,0.138884070186336,0,0,0,0.00452116864385643,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN17","HN28",0.164810965226166 "HALLMARK_COMPLEMENT16",0.0320263006590265,0.0253900594532725,0.0812712257232854,2.05683120192179,37.7474822427877,20.2554614095826,8.43158315793043e-07,9.4667528130563e-06,0.00321090503267371,1.64925684633848e-05,2.18618912704981e-05,-1.44868408870152e-05,-1.44868408870152e-05,1.60195072759893e-06,7.51108621901045e-06,0.0397024656023461,0,0,0,0.00454173866235265,"HALLMARK_COMPLEMENT","kendall_tau","HN17","HN28",0.0505304107666224 "HALLMARK_APICAL_JUNCTION16",0.0342925301648706,0.0250232258855252,0.0918577402905139,2.93138508203088,42.9075885501086,23.0119446712065,1.04753281516999e-06,8.85128213344885e-06,0.00314623822184825,2.95960340481512e-05,7.67650375728922e-06,-3.09758906002571e-05,-3.09758906002571e-05,1.69991490639851e-06,8.33519159755995e-06,0.00337454192115461,0,0,0,0.00518477601243703,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN17","HN28",0.00466877799915037 "HALLMARK_GLYCOLYSIS16",0.0496185977975972,0.0281412606268594,0.0982006027059454,6.87643115516062,34.0023147171315,24.8667101779493,1.09986141890955e-06,8.55530475236943e-06,0.00310727632683014,0.000108496105852552,1.72944008531156e-05,-7.50544319665265e-06,-7.50544319665265e-06,1.94142722125499e-06,7.83771394186598e-06,6.13709083552294e-12,0,0,0,0.00454880373830264,"HALLMARK_GLYCOLYSIS","kendall_tau","HN17","HN28",1.74751061079297e-11 "HALLMARK_PI3K_AKT_MTOR_SIGNALING16",0.0374506024202073,0.0243160904136514,0.0963923271850101,4.88276558665184,41.2712837592584,28.1178022276321,9.01598491064113e-07,6.23436111215978e-06,0.00267132169594452,3.41131460287677e-05,2.732300323109e-05,-2.21294533033749e-05,-2.21294533033749e-05,1.93962217141834e-06,6.47084863151605e-06,1.04608202122769e-06,0,0,0,0.00518891961635565,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN17","HN28",1.93731095584845e-06 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"HALLMARK_XENOBIOTIC_METABOLISM16",0.0394854349115014,0.0284225395269028,0.0946530806285678,2.88290761948719,35.0558662642609,20.4284627671417,1.0266391035251e-06,1.35990680360182e-05,0.0038243570883932,3.89353530383212e-05,3.87435184465573e-05,-2.36744773464549e-05,-2.36744773464549e-05,2.37655224814844e-06,1.04110289364476e-05,0.0039402297699771,0,0,0,0.00503738162451313,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN17","HN28",0.00540059464975882 "HALLMARK_WNT_BETA_CATENIN_SIGNALING16",0.0330011081660574,0.0348460383558539,0.0889934013372443,-0.479834624979884,37.7869795175038,16.0589662755605,1.59311488644775e-06,1.30903661319674e-05,0.00383190305441241,2.4902280348283e-05,1.88230336553158e-05,2.63826900515334e-06,2.63826900515334e-06,2.09569570564129e-06,1.12689262663519e-05,0.631344990097382,0,0,0,0.00557740403018403,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN17","HN28",0.667891505252861 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"EPI_DIFF216",0.0693842542585289,0.0392707563439271,0.165645232815964,6.68198691405937,38.9715083490441,28.1005231215456,2.50576621433529e-06,1.77042920184445e-05,0.00449555983530191,0.000430094389728713,4.47583956599204e-05,-9.07764630814507e-05,-9.07764630814507e-05,6.00107149829752e-06,2.01250651494311e-05,2.35724773034462e-11,0,0,0,0.00839164851636425,"EPI_DIFF2","kendall_tau","HN17","HN28",6.43184067490784e-11 "STRESS16",0.0547433255313161,0.0341771307466914,0.161633132005631,3.98104569493654,38.5156306474463,28.7607771232254,3.39209645168668e-06,2.31957521030005e-05,0.00515634061662796,0.000277948724526474,4.02187181956538e-05,-0.000196894697062328,-0.000196894697062328,7.60191204875785e-06,1.95389988549635e-05,6.86127563689354e-05,0,0,0,0.00945106216662999,"STRESS","kendall_tau","HN17","HN28",0.00010701406033139 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"HALLMARK_ESTROGEN_RESPONSE_EARLY17",0.0416806622224135,0.0648329617331342,0.0905720813474882,-8.71772449695962,14.4127186383062,16.1324083841585,1.59085471790633e-06,5.36227683191947e-06,0.00263687913068191,0.000129409225215387,0.000565527327544448,-8.11462275318825e-05,-8.11462275318825e-05,1.14073009032362e-05,2.44559296099432e-06,0,0,0,0,0.00478559532473377,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN17","HN5",0 "HALLMARK_BILE_ACID_METABOLISM17",0.0500296841862191,0.0620953382147412,0.0820398089987642,-5.71273351318936,12.7104695307142,17.1729131818859,1.23480953462695e-06,3.12600128117243e-06,0.00208825544792762,7.51178742554471e-05,0.000311048090280473,-1.13372605278373e-05,-1.13372605278373e-05,6.24236960650082e-06,1.24882959196531e-06,1.1117570641872e-08,0,0,0,0.0035389867744608,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN17","HN5",2.43016042283299e-08 "HALLMARK_MITOTIC_SPINDLE17",0.0844883216857984,0.0868388982451834,0.1145777803536,-0.652069428419501,9.09430128883916,11.3421936517883,2.53585304958983e-06,1.03586933251022e-05,0.00359089771153288,0.000300262024654434,0.000583898761379469,0.000108386192222787,0.000108386192222787,1.0846872832103e-05,5.88113759840943e-06,0.514356384843346,0,0,0,0.00454788269184721,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN17","HN5",0.556470201081669 "HALLMARK_INFLAMMATORY_RESPONSE17",0.032999325922355,0.0567048611476995,0.072383327030375,-8.82406850729894,12.6270139315899,12.6479271486435,9.02805063827062e-07,6.21427940401712e-06,0.00266778643595101,5.81817279338313e-05,0.000541799909954991,-3.81687996487625e-05,-3.81687996487625e-05,9.62833126747167e-06,1.43662685789916e-06,0,0,0,0,0.00411365466926435,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN17","HN5",0 "HALLMARK_ESTROGEN_RESPONSE_LATE17",0.0483822696424001,0.0690578628102066,0.0892127325910421,-7.4927987429239,14.3717894249188,14.0233013574222,1.39549393727145e-06,6.11876814022956e-06,0.0027412154379948,0.000112629743822345,0.000380553595872683,-4.57597056512356e-05,-4.57597056512356e-05,7.97136370609161e-06,1.96566294544415e-06,6.75015598972095e-14,0,0,0,0.0041578526010534,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN17","HN5",2.28766093484491e-13 "HALLMARK_ADIPOGENESIS17",0.0399082285013679,0.0564948200342657,0.0737213946915439,-7.2690504707845,11.7041199709266,13.4938699679875,9.26812444100388e-07,4.17984410437868e-06,0.00225979126214769,9.1029355925064e-05,0.000447409784412506,-3.01856011005585e-05,-3.01856011005585e-05,8.24630302745887e-06,1.52976437251364e-06,3.61932706027801e-13,0,0,0,0.00366985611904561,"HALLMARK_ADIPOGENESIS","kendall_tau","HN17","HN5",1.15035908726674e-12 "HALLMARK_P53_PATHWAY17",0.0504327851840949,0.0727310000931841,0.101535741802636,-7.7791525682629,14.2342959396766,15.2743318601144,1.82731275605754e-06,6.28897451580594e-06,0.00284890983919525,0.000255945497824624,0.000609823212907755,-8.94531858640635e-05,-8.94531858640635e-05,1.27890252131076e-05,3.45634206167316e-06,7.32747196252603e-15,0,0,0,0.00501747843773093,"HALLMARK_P53_PATHWAY","kendall_tau","HN17","HN5",2.70128746957073e-14 "HALLMARK_HEME_METABOLISM17",0.0374555938021136,0.0592759591717066,0.0746196848103021,-9.5037779876033,13.7708430989046,12.4754065864448,1.13653138011851e-06,4.03493537264672e-06,0.00227408591587153,5.61023516028004e-05,0.000378624742168735,-1.86127055923262e-05,-1.86127055923262e-05,7.18326261357911e-06,1.41269799502527e-06,0,0,0,0,0.0039164752121711,"HALLMARK_HEME_METABOLISM","kendall_tau","HN17","HN5",0 "HALLMARK_CHOLESTEROL_HOMEOSTASIS17",0.0432496542085583,0.0651818153351582,0.100341883862636,-7.84089855337027,15.1812973664215,16.7503996731767,1.89122721726703e-06,5.83281501051664e-06,0.00277921611750214,0.000184991914842666,0.000681069099428666,-0.000117629155148684,-0.000117629155148684,1.40428271578263e-05,4.30604651501819e-06,4.44089209850063e-15,0,0,0,0.00533771002588392,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN17","HN5",1.66852687151333e-14 "HALLMARK_NOTCH_SIGNALING17",0.0318445510106457,0.0555105703155775,0.0642836039742636,-10.0581018526963,16.7406536429659,7.28961684971043,1.21138260932817e-06,4.22490151981498e-06,0.00233158403861906,3.42242138760196e-05,0.000154464235335001,-2.83073645718441e-06,-2.83073645718441e-06,3.6548406536868e-06,1.34840557347068e-06,0,0,3.10862446895044e-13,0,0.00349764057927883,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN17","HN5",0 "HALLMARK_ALLOGRAFT_REJECTION17",0.035556316312462,0.0463594283966109,0.0617737229651343,-5.85991021644114,13.1774029440708,14.5567201060847,7.30732681513445e-07,2.56799086294755e-06,0.00181623884565357,5.70125494679607e-05,0.000176021508139724,-2.70366126766844e-05,-2.70366126766844e-05,3.85840118887724e-06,1.02129592841263e-06,4.63117499904797e-09,0,0,0,0.00274621034759835,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN17","HN5",1.03541098838031e-08 "HALLMARK_INTERFERON_GAMMA_RESPONSE17",0.0324665004454995,0.0575941779952491,0.0736014151256592,-10.0961740412546,12.114678830387,11.2145557424783,8.30813010936255e-07,5.2634699967264e-06,0.00246866016447438,5.94575288237805e-05,0.000674232580255494,-2.92868831135345e-05,-2.92868831135345e-05,1.14291527029278e-05,1.93736391245273e-06,0,0,0,0,0.00433974471572519,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN17","HN5",0 "HALLMARK_ANDROGEN_RESPONSE17",0.0410608749370838,0.0549615558570782,0.0772144283175491,-6.43289045335186,14.6352029337662,17.7183649107931,1.29212593886654e-06,3.27726071299114e-06,0.00213761237174977,0.000116029952114759,0.000251503286130521,-4.99076547260825e-05,-4.99076547260825e-05,6.00245351378065e-06,1.47733839229251e-06,1.25199850486979e-10,0,0,0,0.0036223253019767,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN17","HN5",3.1869052851231e-10 "HALLMARK_TNFA_SIGNALING_VIA_NFKB17",0.0389103836396684,0.0661883137987541,0.0961279884269834,-8.86885202508858,14.6104775208651,14.8740753720787,2.09933477549648e-06,7.26059709165276e-06,0.00305940057317593,0.000130803373633682,0.000777589355275577,-9.36482905461197e-05,-9.36482905461197e-05,1.52366507022607e-05,3.95167122303096e-06,0,0,0,0,0.00559746288788526,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN17","HN5",0 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"HALLMARK_UNFOLDED_PROTEIN_RESPONSE17",0.0588164433529175,0.0826319874827337,0.0989610527856797,-8.04064767211004,10.3834414746363,9.3627440073449,1.65395214475087e-06,7.0188624738375e-06,0.00294496428137734,0.000146147946350884,0.000845141751064584,-1.12803867673194e-05,-1.12803867673194e-05,1.48476126563051e-05,2.94169982836924e-06,8.88178419700125e-16,0,0,0,0.00480901047453465,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN17","HN5",3.5527136788005e-15 "HALLMARK_MTORC1_SIGNALING17",0.0507147656862187,0.061613676705554,0.0883933461972913,-4.65619958172214,12.9530558663648,15.3298706333208,1.45076123677155e-06,3.92826069551633e-06,0.00231927185389895,0.000186141557942599,0.000380367967569061,-5.52325637585135e-05,-5.52325637585135e-05,8.3614460295e-06,2.95164103151345e-06,3.22099707017465e-06,0,0,0,0.00388600262652806,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN17","HN5",5.66202175564333e-06 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"HALLMARK_KRAS_SIGNALING_UP17",0.0396944937481275,0.0653632732002873,0.084695801968052,-9.24746903822192,12.9969139471644,13.0869126649831,9.76963322821711e-07,6.62789513970758e-06,0.00275769078442985,0.000100807932355715,0.000673217224692248,-4.60495438312594e-05,-4.60495438312594e-05,1.18886364735703e-05,2.08224205925115e-06,0,0,0,0,0.00457589449508629,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN17","HN5",0 "HALLMARK_HYPOXIA17",0.0358540464133322,0.0532235578616738,0.0751740327599099,-8.05217145201716,15.502734319941,15.430045060092,1.02304049770272e-06,3.53013228631673e-06,0.00213381648321018,8.59547944287243e-05,0.00030460846179396,-4.15011689321588e-05,-4.15011689321588e-05,6.33294899578277e-06,1.92373411392964e-06,8.88178419700125e-16,0,0,0,0.00377823169311867,"HALLMARK_HYPOXIA","kendall_tau","HN17","HN5",3.5527136788005e-15 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"HALLMARK_APOPTOSIS17",0.0428782436782635,0.0625952675920229,0.0881512556500389,-7.62263395612586,14.2824737935811,17.7577712938612,1.36416886710757e-06,5.22654713579274e-06,0.00256723898437608,0.000112223030956267,0.000504246623334996,-5.91948808980102e-05,-5.91948808980102e-05,9.94782137073875e-06,1.97113513619536e-06,2.48689957516035e-14,0,0,0,0.00445423984873435,"HALLMARK_APOPTOSIS","kendall_tau","HN17","HN5",8.67832017919458e-14 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY17",0.0305115351644373,0.0563217049057965,0.0654591185021825,-12.6321304193815,13.7905636597148,8.32379550265431,7.612976317555e-07,3.3134335879525e-06,0.00201859634887909,3.0725743329814e-05,0.000358005166206517,-1.024920675493e-05,-1.024920675493e-05,6.32199944367632e-06,1.10504638035724e-06,0,0,0,0,0.00367428831655623,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN17","HN5",0 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"HALLMARK_XENOBIOTIC_METABOLISM17",0.0394854349115014,0.0641057617349525,0.0809104818529554,-10.2262087536432,13.4566270338523,12.2561441133127,1.0266391035251e-06,4.66976051773683e-06,0.00238671314180442,7.08379042621806e-05,0.000515501566916557,-3.64047734557277e-05,-3.64047734557277e-05,9.3766226383132e-06,1.7799870145452e-06,0,0,0,0,0.00423823652272368,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN17","HN5",0 "HALLMARK_WNT_BETA_CATENIN_SIGNALING17",0.0330011081660574,0.058516939113954,0.0761358186367287,-7.76013780231752,16.1072122020546,9.01102195904786,1.59311488644775e-06,9.1182510028429e-06,0.00327282231251418,7.02963134291855e-05,0.000317427557678693,-4.3534504748022e-05,-4.3534504748022e-05,7.07154972616706e-06,3.72303677550426e-06,8.43769498715119e-15,0,0,0,0.00435011536904183,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN17","HN5",3.09119292987221e-14 "HALLMARK_KRAS_SIGNALING_DN17",0.056252546393854,0.0818373358338507,0.102938264892634,-8.26864640242781,12.1381920028701,13.0967406248842,1.68822761787827e-06,7.78580391739811e-06,0.0030779914774535,9.81106168594752e-05,0.000807050612988601,-5.46204811383549e-05,-5.46204811383549e-05,1.46931304926364e-05,2.49583271564547e-06,2.22044604925031e-16,0,0,0,0.00502326434634229,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN17","HN5",9.39296602128909e-16 "HALLMARK_COAGULATION17",0.040956776475856,0.0676891897901491,0.0859942767329674,-9.54354628540662,13.4459457265954,12.4333991767969,1.16507940706231e-06,6.58107347569357e-06,0.00278319113299031,4.53401269984981e-05,0.000627484139819574,-3.72399699875088e-05,-3.72399699875088e-05,1.11193022295865e-05,2.06752361596027e-06,0,0,0,0,0.00461864155200183,"HALLMARK_COAGULATION","kendall_tau","HN17","HN5",0 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"PEMT17",0.0662761575411479,0.105093906043703,0.1670295172439,-8.61749455728278,16.7189092647993,19.7010985941981,5.81476184710602e-06,1.4376013770484e-05,0.00449341469459363,0.000597465166481514,0.00158470164195941,-0.000407459901611423,-0.000407459901611423,3.62164335627428e-05,9.78325421937054e-06,0,0,0,0,0.00910338596294589,"PEMT","kendall_tau","HN17","HN5",0 "EPI_DIFF117",0.0464511765904416,0.0925990798989442,0.124481417522123,-10.1449851438044,14.160066509192,12.6774115165183,2.82577605145866e-06,1.77661595076965e-05,0.00453783379589371,0.000148010496315626,0.00170244869076519,-0.000130561632633693,-0.000130561632633693,3.02665399027245e-05,6.22468844486157e-06,0,0,0,0,0.00772387989665641,"EPI_DIFF1","kendall_tau","HN17","HN5",0 "EPI_DIFF217",0.0693842542585289,0.0922882374171384,0.125392386095235,-6.82750898695425,10.856949963427,11.2529648760075,2.50576621433529e-06,8.64798915638878e-06,0.00333972384647654,0.000459866626302308,0.00145929370977914,-6.87015523153488e-05,-6.87015523153488e-05,2.65125506652572e-05,8.55427957842025e-06,8.64019966684282e-12,0,0,0,0.00620703121684112,"EPI_DIFF2","kendall_tau","HN17","HN5",2.4425179827421e-11 "STRESS17",0.0547433255313161,0.0876117851916326,0.129062784313043,-8.47079812149339,14.2461868492703,16.63758721377,3.39209645168668e-06,1.15639186087062e-05,0.00386730074604923,0.000394993733952874,0.00133505032967559,-0.000214483090401276,-0.000214483090401276,2.7114966519318e-05,6.10710820290421e-06,0,0,0,0,0.00717264559400122,"STRESS","kendall_tau","HN17","HN5",0 "HYPOXIA17",0.0544872438607883,0.0791745998181354,0.116459344177894,-7.3556416180793,16.4429338070896,18.8124865323776,2.34977903528932e-06,8.81462022237343e-06,0.00334131699448926,0.000352273646259118,0.000611105181136365,-0.00012923702306526,-0.00012923702306526,1.41047571563138e-05,3.82798603772243e-06,1.90070181815827e-13,0,0,0,0.00573845872755132,"HYPOXIA","kendall_tau","HN17","HN5",6.24364619596124e-13 "HALLMARK_PANCREAS_BETA_CELLS18",0.0480557469590371,0.0469384018164506,0.124361192510403,0.208549519190008,20.6522203246407,12.8676565642881,7.65496427001669e-06,2.09499533501288e-05,0.00534835653450156,8.86105109545801e-05,0.000139474261953369,-5.20627996039814e-05,-5.20627996039814e-05,1.35514117503696e-05,3.61025131893764e-05,0.834799921780744,0,0,0,0.00676249327233293,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN22","HN28",0.860407281344571 "HALLMARK_MYOGENESIS18",0.0420113457187662,0.0386590268415247,0.105447266049452,0.784939623232204,25.438781100743,17.0211703895568,5.49433243928768e-06,1.26453864279999e-05,0.00425907488397277,5.36207506800154e-05,2.20328373541079e-05,1.0826743721922e-05,1.0826743721922e-05,6.11838910102662e-06,1.52964696235009e-05,0.432488969034694,0,0,0,0.00565915265225406,"HALLMARK_MYOGENESIS","kendall_tau","HN22","HN28",0.474446854090299 "HALLMARK_IL2_STAT5_SIGNALING18",0.0368007893047348,0.0253116190709646,0.08069779621617,3.31995783732619,22.2467015341977,17.5669733237622,4.32358195375476e-06,7.55242920943943e-06,0.00344615889987595,5.12566249540151e-05,1.46549179837578e-05,3.92182771649474e-05,3.92182771649474e-05,3.79348550122974e-06,9.84051527878827e-06,0.000900310442341956,0,0,0,0.00413538561914343,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN22","HN28",0.00129750622572811 "HALLMARK_ESTROGEN_RESPONSE_EARLY18",0.0417217049497595,0.0298062875352372,0.0983122107771899,2.89219280052271,23.3435103298927,19.5697277925475,7.60978419487775e-06,9.26342798990488e-06,0.00410770156958641,9.15256795270027e-05,4.58684772697317e-05,0.000110689713800063,0.000110689713800063,5.77698825154814e-06,1.21542483464316e-05,0.00382563102297095,0,0,0,0.00568305041984254,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN22","HN28",0.00525577346146477 "HALLMARK_BILE_ACID_METABOLISM18",0.0435580324663076,0.0274662946919044,0.0957120488274413,4.52683277584307,24.601309279052,21.0105529138474,4.67939272334531e-06,7.85682180237724e-06,0.00354065170918046,2.22067814603828e-05,1.60374454267979e-05,2.56710489860319e-05,2.56710489860319e-05,4.39426913489591e-06,1.04505794322684e-05,5.98742821034115e-06,0,0,0,0.0044342775290648,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN22","HN28",1.02343249641878e-05 "HALLMARK_MITOTIC_SPINDLE18",0.0753491428084734,0.0398244882951342,0.130258553476544,6.62120450135346,11.5850127230903,20.7572889683256,1.56059687047878e-05,1.30803230487055e-05,0.00535595852798482,0.000620588064791212,2.92356409905756e-05,-2.47114375146289e-05,-2.47114375146289e-05,2.23646954288536e-05,1.88811641351984e-05,3.56283891278508e-11,0,0,0,0.00594590052796712,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN22","HN28",9.47940851003452e-11 "HALLMARK_INFLAMMATORY_RESPONSE18",0.031602112600324,0.0292877915074263,0.0857762834973133,0.591740020637991,29.833830063821,14.1235445034106,2.607723170317e-06,1.25885398267357e-05,0.00389823844794706,2.551800105563e-05,4.89200156800571e-05,2.43346094541234e-05,2.43346094541234e-05,3.19736120244067e-06,1.5896779427368e-05,0.554024692919985,0,0,0,0.00474135508084849,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN22","HN28",0.594464451527284 "HALLMARK_ESTROGEN_RESPONSE_LATE18",0.0485605638218152,0.0337243534746905,0.112474485565767,3.30279927643101,21.3840180013793,19.889930639497,1.00310686637637e-05,1.00470932534805e-05,0.00448086620166729,0.000133476833440326,4.91296636757847e-05,0.000104651549705548,0.000104651549705548,8.83330805641833e-06,1.55760285061304e-05,0.000957248810443234,0,0,0,0.00628177952527347,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN22","HN28",0.00137787588871633 "HALLMARK_ADIPOGENESIS18",0.0330938335475744,0.0239024390243902,0.0858557521105467,2.73104344619271,31.2051201872592,19.8642190869269,3.07107281222877e-06,8.15568455239219e-06,0.00335063536730289,2.67623106474128e-05,2.13645290275451e-05,3.14818949523044e-05,3.14818949523044e-05,2.75883729647633e-06,9.62716044260645e-06,0.00631341481910708,0,0,0,0.00447194950150485,"HALLMARK_ADIPOGENESIS","kendall_tau","HN22","HN28",0.00849493801747131 "HALLMARK_P53_PATHWAY18",0.0454389451888412,0.0312095845079054,0.119679500185906,3.07888635317559,28.316931720512,19.5925353000017,7.16668283262745e-06,1.40924422171878e-05,0.00461076187303305,6.82788208708086e-05,3.42015925673365e-05,5.35782085149235e-05,5.35782085149235e-05,6.77369143577743e-06,2.02896584472968e-05,0.00207775925521969,0,0,0,0.00631659340638784,"HALLMARK_P53_PATHWAY","kendall_tau","HN22","HN28",0.00290540414285179 "HALLMARK_HEME_METABOLISM18",0.0378211023784354,0.0262893736977571,0.0953570733355237,3.26815960803165,30.2484960363815,20.0475484443434,3.77077605255961e-06,8.57959558686389e-06,0.00351430955372794,3.76186025123886e-05,1.76827899296319e-05,2.97548595600211e-05,2.97548595600211e-05,3.51802297545174e-06,1.17693637676193e-05,0.00108249301355978,0,0,0,0.00478081605491951,"HALLMARK_HEME_METABOLISM","kendall_tau","HN22","HN28",0.00154679439118627 "HALLMARK_CHOLESTEROL_HOMEOSTASIS18",0.0424846473959409,0.0266793689780659,0.108331355948345,4.15818249220547,27.1838871788811,21.9313589273986,5.44442682290112e-06,8.90322310898626e-06,0.00378782918462374,6.10186517731835e-05,4.97652495663574e-05,4.17566319118939e-05,4.17566319118939e-05,5.76739091135089e-06,1.37612510697787e-05,3.20789712109359e-05,0,0,0,0.00551401979772434,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN22","HN28",5.13962808502189e-05 "HALLMARK_NOTCH_SIGNALING18",0.0303404303219374,0.0241787962234461,0.0854398210897262,1.63874076400196,22.7955538354201,19.7480134130478,3.99804513530041e-06,1.00394118103095e-05,0.00374665943816755,7.97682234445728e-05,2.58480852455105e-05,-1.31976828869414e-05,-1.31976828869414e-05,5.74242703710439e-06,9.52324824292199e-06,0.101267260523982,0,0,0,0.0047843498536972,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN22","HN28",0.122269300180907 "HALLMARK_ALLOGRAFT_REJECTION18",0.0340806200565269,0.023572820941242,0.0697241840681501,3.75980815538021,22.840471240706,16.1387316299302,1.8746436659711e-06,5.83609580121254e-06,0.00277682182849092,4.92903186800654e-05,1.04731735118746e-05,6.21754784818846e-06,6.21754784818846e-06,2.33529807603317e-06,8.07768289882601e-06,0.000170043705332912,0,0,0,0.00297131412228529,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN22","HN28",0.000258695210183059 "HALLMARK_INTERFERON_GAMMA_RESPONSE18",0.0290458811082174,0.0241889664686802,0.0894989654208707,1.45495114874742,36.3676130888725,19.6500924954652,2.5794971410895e-06,8.46406702391754e-06,0.00332318584569191,2.69203380342427e-05,4.22133913153024e-05,3.48713174295576e-05,3.48713174295576e-05,2.66316825555506e-06,1.09466388457432e-05,0.145682786118071,0,0,0,0.00509035528891022,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN22","HN28",0.171838471890523 "HALLMARK_ANDROGEN_RESPONSE18",0.0374515414794577,0.0239950726779995,0.0793043159614178,3.87805349580403,22.6861627286711,18.6733716281687,4.91528865310397e-06,7.0249369991801e-06,0.00345546316031355,9.98470351124686e-05,4.61928502969722e-05,0.00010643029883256,0.00010643029883256,3.30350521723822e-06,8.67303682968186e-06,0.000105295566752206,0,0,0,0.00451196573970124,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN22","HN28",0.000161654812663961 "HALLMARK_TNFA_SIGNALING_VIA_NFKB18",0.0380961279836012,0.0342310332148548,0.105473807858724,0.819216142220831,27.8247610533789,15.2503992934723,5.35121916971442e-06,1.68086850490115e-05,0.00470743074497394,6.70104466330666e-05,4.64122802981224e-05,3.81595247477724e-05,3.81595247477724e-05,5.76366590240505e-06,2.17232396118269e-05,0.412663106701828,0,0,0,0.00599874945504925,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN22","HN28",0.454313408108051 "HALLMARK_PEROXISOME18",0.0377547296106296,0.0219372901895781,0.0923702935228221,5.21690831144312,26.6422473567729,25.4589587605853,3.7911824798885e-06,5.30157815211407e-06,0.00301542047349993,5.29991766159629e-05,1.71168710681943e-05,1.6413042420494e-05,1.6413042420494e-05,4.10233946726472e-06,7.55369479419924e-06,1.81934259879668e-07,0,0,0,0.00442126107088704,"HALLMARK_PEROXISOME","kendall_tau","HN22","HN28",3.60800488395429e-07 "HALLMARK_INTERFERON_ALPHA_RESPONSE18",0.0372582289083985,0.0345020673954166,0.121900741480783,0.59406934313758,37.3354526731792,18.9354365663074,4.39515120262435e-06,1.70294466087196e-05,0.00462867127924893,4.28450574130584e-05,7.5076940111737e-05,4.60137369737287e-05,4.60137369737287e-05,5.03965834825677e-06,2.12038964843119e-05,0.552465734416328,0,0,0,0.0071314895362045,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN22","HN28",0.593333062715618 "HALLMARK_TGF_BETA_SIGNALING18",0.0323103764477756,0.0321453529000699,0.0970035301536885,0.0372635675289746,28.9633834585042,15.346481983998,3.8828206755302e-06,1.5629228657156e-05,0.00441724454073874,3.43976588739938e-05,4.71083218818655e-05,1.28462814976489e-05,1.28462814976489e-05,4.88905231155425e-06,1.77612484191717e-05,0.97027485420546,0,0,0,0.00568457410429467,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN22","HN28",0.975250622688565 "HALLMARK_FATTY_ACID_METABOLISM18",0.032447008842743,0.0245431376751887,0.0904865577335132,2.38932332753181,31.5482186168558,21.0687757560124,3.4455372688468e-06,7.39729793394906e-06,0.00329284606424228,2.8951284762645e-05,2.42440853785945e-05,2.96195311093668e-05,2.96195311093668e-05,3.28453004060024e-06,9.69635090872509e-06,0.0168794400627004,0,0,0,0.00490271647998886,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN22","HN28",0.0220313224347787 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE18",0.0517290058487894,0.031972172520953,0.120140063276464,3.83888831132441,25.391114735185,21.2404361083386,9.49810345496811e-06,1.68883444064149e-05,0.0051367740714755,9.55558171166927e-05,1.34745362802748e-05,0.000103248433435633,0.000103248433435633,7.15920516345208e-06,1.71303477910172e-05,0.000123592631547043,0,0,0,0.006287402819072,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN22","HN28",0.000189005116644112 "HALLMARK_MTORC1_SIGNALING18",0.0474205881995077,0.0270704743228337,0.0967559719070862,5.34754797136349,21.7882910066126,21.009160601878,6.13279047637927e-06,8.24906834099525e-06,0.00379234212820712,0.000103734558928746,1.08226542035808e-05,6.66813418333176e-05,6.66813418333176e-05,5.02708699321482e-06,1.09018927982093e-05,8.91537863534353e-08,0,0,0,0.00463111494058468,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN22","HN28",1.8202231380493e-07 "HALLMARK_UV_RESPONSE_UP18",0.0407477310721495,0.0291982997333115,0.0989169231815464,3.24303114312059,24.7538514875103,21.4657261793545,4.98886132111835e-06,7.59405024111176e-06,0.00354723999219536,9.48958219974348e-05,2.26805875802351e-05,2.72937845971939e-05,2.72937845971939e-05,5.42205212866149e-06,1.04488820658806e-05,0.00118265283165719,0,0,0,0.00505809932651539,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN22","HN28",0.00168581785458044 "HALLMARK_ANGIOGENESIS18",0.0434293491407863,0.0353735965931088,0.124765841295868,1.35799675392205,22.1741227905789,15.8490900110208,8.71811740362774e-06,2.63715183083295e-05,0.00592365053931756,0.00018358919770866,3.96343728321039e-05,-6.32855967357829e-05,-6.32855967357829e-05,1.33548227403246e-05,3.17120035283744e-05,0.174464714174715,0,0,0,0.0069333138788023,"HALLMARK_ANGIOGENESIS","kendall_tau","HN22","HN28",0.203946822931873 "HALLMARK_MYC_TARGETS_V118",0.0713302600555415,0.0414086941234876,0.160074513859219,5.84167032870958,24.2236487768428,25.7552593985039,1.07072596481042e-05,1.54285546639395e-05,0.00511231985619482,0.000351297211477388,1.20476391067166e-05,1.87922551153942e-05,1.87922551153942e-05,1.3321509470885e-05,2.11285059914474e-05,5.16800002792195e-09,0,0,0,0.00711029467750356,"HALLMARK_MYC_TARGETS_V1","kendall_tau","HN22","HN28",1.15105455167352e-08 "HALLMARK_DNA_REPAIR18",0.0568325963390769,0.0348584342486781,0.143482683027159,5.06640022732838,30.7112025072834,26.3383995863525,7.31222805731788e-06,1.13993686020456e-05,0.00432569031015438,0.000110406142635969,6.2416227897228e-05,5.65780809582989e-05,5.65780809582989e-05,7.86057355653573e-06,1.69088443790045e-05,4.05409083858999e-07,0,0,0,0.00692362104377932,"HALLMARK_DNA_REPAIR","kendall_tau","HN22","HN28",7.81575545275709e-07 "HALLMARK_KRAS_SIGNALING_UP18",0.0422857685942802,0.0337291285201568,0.0909737800864885,2.07259233481834,22.7389854372063,16.54309730288,5.6006142329224e-06,1.13436694209851e-05,0.00411634348104085,6.91070130188712e-05,3.08269326842036e-05,7.28463559804622e-05,7.28463559804622e-05,4.48460483394682e-06,1.18739153674209e-05,0.0382102350078601,0,0,0,0.00492077816249257,"HALLMARK_KRAS_SIGNALING_UP","kendall_tau","HN22","HN28",0.0487366988820429 "HALLMARK_HYPOXIA18",0.0358656907955244,0.0261233607059689,0.0830132163172905,2.84840061203369,24.3442098458868,17.9149207840709,4.73378368601892e-06,6.86453746230574e-06,0.00340563080035471,4.80487325083632e-05,3.26863364877869e-05,6.79478210218361e-05,6.79478210218361e-05,3.65082189616617e-06,9.98416350495938e-06,0.00439395752267102,0,0,0,0.00458638547970107,"HALLMARK_HYPOXIA","kendall_tau","HN22","HN28",0.00600150295779457 "HALLMARK_SPERMATOGENESIS18",0.0484391956441972,0.0357384592301152,0.125923376702764,2.84264082740028,31.9376454378234,20.8810292429273,5.62493307005152e-06,1.42375162834665e-05,0.00445673079212981,7.86140711461249e-05,4.07415268733093e-05,4.44242072733655e-05,4.44242072733655e-05,5.78600062940446e-06,1.85536584796001e-05,0.00447414599253459,0,0,0,0.00639337748315456,"HALLMARK_SPERMATOGENESIS","kendall_tau","HN22","HN28",0.00609686638148399 "HALLMARK_OXIDATIVE_PHOSPHORYLATION18",0.0562728269757935,0.0413519927798638,0.147305538147842,2.75992242063323,28.396193256759,19.79674446464,7.03857691010271e-06,2.20889762928089e-05,0.00539699483072863,6.64562291072292e-05,0.000217979838836528,8.14083885293717e-05,8.14083885293717e-05,1.01771976307681e-05,2.85446442125218e-05,0.00578150890407247,0,0,0,0.00769666315312642,"HALLMARK_OXIDATIVE_PHOSPHORYLATION","kendall_tau","HN22","HN28",0.00780603268793253 "HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION18",0.0393644336194575,0.0335881848265719,0.108509971460088,1.33324689555963,28.3655759390464,16.7607001876752,3.99366423762949e-06,1.46766100655566e-05,0.00432091128156852,9.98559491428661e-05,5.41604555739893e-05,9.27028205060208e-06,9.27028205060208e-06,5.84217046264763e-06,1.98816770481107e-05,0.18245079441707,0,0,0,0.00580309180514034,"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION","kendall_tau","HN22","HN28",0.211995921679851 "HALLMARK_MYC_TARGETS_V218",0.0540463132252193,0.0362341935579065,0.13967958038866,3.80039947693952,31.7817575745874,24.202417201528,6.92750611468053e-06,1.4939592976788e-05,0.00467622701453517,0.000123178888883066,1.76000147602551e-05,3.66524586787762e-05,3.66524586787762e-05,7.15987606289876e-06,1.81685790965403e-05,0.000144463012677898,0,0,0,0.006867249688524,"HALLMARK_MYC_TARGETS_V2","kendall_tau","HN22","HN28",0.000220348252800529 "HALLMARK_E2F_TARGETS18",0.063621740375399,0.0366073407193643,0.121317748297698,6.45880118214511,17.3997107860563,23.7442523698988,8.52679466606864e-06,8.86711215695736e-06,0.00417060029528436,0.000304244511503526,1.39347681083236e-05,1.57090065169988e-05,1.57090065169988e-05,1.08953097937069e-05,1.26278938146659e-05,1.05535580274818e-10,0,0,0,0.00518041190142279,"HALLMARK_E2F_TARGETS","kendall_tau","HN22","HN28",2.70391813514567e-10 "HALLMARK_IL6_JAK_STAT3_SIGNALING18",0.0269314635998066,0.0234080492368677,0.076201329593977,1.33339652810664,29.1101534272089,17.7559048986067,1.99716914284304e-06,4.88529639327405e-06,0.00262344535603795,3.06678218295955e-05,4.58882930245239e-05,1.81309602919283e-05,1.81309602919283e-05,2.7646645470356e-06,8.74039511053711e-06,0.182401711166062,0,0,0,0.00421617481593881,"HALLMARK_IL6_JAK_STAT3_SIGNALING","kendall_tau","HN22","HN28",0.211995921679851 "HALLMARK_PROTEIN_SECRETION18",0.0456307143731712,0.033604514334617,0.126259110833037,2.40109330508967,29.9172490450834,20.2058545326065,5.56960087161897e-06,1.94168239937245e-05,0.00499864230220001,0.000127539111143684,1.17941566505214e-05,-6.96919390137142e-06,-6.96919390137142e-06,7.1632790839838e-06,2.09271055166764e-05,0.0163461679393679,0,0,0,0.00648294364569163,"HALLMARK_PROTEIN_SECRETION","kendall_tau","HN22","HN28",0.0213589927741074 "HALLMARK_UV_RESPONSE_DN18",0.0352100956537646,0.0257200286163701,0.0941897851869157,2.49339158437258,26.8838964337893,21.6324308730315,4.73152395225638e-06,9.65477961815881e-06,0.00379292809982146,3.85544309916882e-05,3.17172970447331e-05,3.3202534082444e-05,3.3202534082444e-05,4.71305181236329e-06,9.91813589325079e-06,0.0126529218195035,0,0,0,0.00517580435372952,"HALLMARK_UV_RESPONSE_DN","kendall_tau","HN22","HN28",0.0166441119236422 "HALLMARK_APOPTOSIS18",0.0385908379564059,0.026967788971368,0.098385709002583,2.80202687082564,27.3688262877808,18.9508982357841,5.50621069516156e-06,1.16004083982663e-05,0.00413601488070678,6.56726931447128e-05,2.01617471243878e-05,5.58278762841061e-05,5.58278762841061e-05,4.67326472593466e-06,1.41021729272806e-05,0.00507826436620173,0,0,0,0.00532171088462478,"HALLMARK_APOPTOSIS","kendall_tau","HN22","HN28",0.00688022914130558 "HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY18",0.0325616252866878,0.0262855079984657,0.0903486008017521,1.9210644536294,30.5008964634196,19.6036041075445,3.28069394881796e-06,7.29259409276332e-06,0.00325165927513651,3.81184966323257e-05,2.73537676946517e-05,2.31656170577655e-05,2.31656170577655e-05,3.48950631203078e-06,1.05793287546554e-05,0.0547235822731107,0,0,0,0.00489120060046,"HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY","kendall_tau","HN22","HN28",0.0687552700354468 "HALLMARK_COMPLEMENT18",0.030843049723423,0.0253900594532725,0.0813748340206986,1.53075975543638,27.1815675557286,16.4258181630929,3.12306461555391e-06,9.4667528130563e-06,0.00354821327270645,3.42865775822526e-05,2.07059011466827e-05,1.66646732666746e-05,1.66646732666746e-05,3.35605201083839e-06,1.15167821737103e-05,0.125828779301635,0,0,0,0.00440522791920281,"HALLMARK_COMPLEMENT","kendall_tau","HN22","HN28",0.15038073623854 "HALLMARK_APICAL_JUNCTION18",0.0344037449746954,0.0250232258855252,0.0926661592446759,2.59574358105108,28.8312439333438,20.2291028300051,4.10832660081842e-06,8.85128213344885e-06,0.00359994565712696,3.4947609475363e-05,1.37053906875285e-05,2.2390326474447e-05,2.2390326474447e-05,3.98366579706692e-06,1.10812825257272e-05,0.00943864749591938,0,0,0,0.00492957975022056,"HALLMARK_APICAL_JUNCTION","kendall_tau","HN22","HN28",0.0125139227228875 "HALLMARK_GLYCOLYSIS18",0.0467165364182854,0.0281412606268594,0.0950040261158261,4.58910494615976,18.6768370962212,20.19206488688,7.72849239191954e-06,8.55530475236943e-06,0.00403531871656862,0.000109164551912714,8.54396666933113e-06,6.75273967098529e-05,6.75273967098529e-05,6.58440253778054e-06,1.08649638536547e-05,4.45150600891786e-06,0,0,0,0.0049002520435219,"HALLMARK_GLYCOLYSIS","kendall_tau","HN22","HN28",7.68718218280089e-06 "HALLMARK_PI3K_AKT_MTOR_SIGNALING18",0.0346863386814961,0.0243160904136514,0.0948329425578862,3.35161728553303,31.0917293480271,24.8208553708948,3.23911072966883e-06,6.23436111215978e-06,0.00307790055749509,4.12160021812623e-05,1.60867624067074e-05,9.98340448947347e-06,9.98340448947347e-06,3.64224712638051e-06,7.97146460333229e-06,0.000803409996109838,0,0,0,0.00483928405059863,"HALLMARK_PI3K_AKT_MTOR_SIGNALING","kendall_tau","HN22","HN28",0.00116445822329129 "HALLMARK_G2M_CHECKPOINT18",0.0742944461661677,0.0395772766270376,0.125203528402414,7.15940165777749,11.7621921553527,21.7665923152859,1.31471028576815e-05,1.02673655282113e-05,0.00483884990322006,0.000550596418309467,1.19312801892535e-05,-1.69074317680866e-05,-1.69074317680866e-05,1.86332873838499e-05,1.53750827819701e-05,8.10240763371439e-13,0,0,0,0.00543076047903836,"HALLMARK_G2M_CHECKPOINT","kendall_tau","HN22","HN28",2.48136233782503e-12 "HALLMARK_APICAL_SURFACE18",0.035877267021045,0.0334734182436962,0.0820466277574816,0.515196558515749,21.1045116135803,11.442966619388,6.71490711194871e-06,1.49555917136083e-05,0.00465515830295351,0.000102363000433452,5.04266599307334e-05,0.000122545922402072,0.000122545922402072,4.68582825882083e-06,1.79184047975736e-05,0.606415673672569,0,0,0,0.00535500532278844,"HALLMARK_APICAL_SURFACE","kendall_tau","HN22","HN28",0.644796412512605 "HALLMARK_XENOBIOTIC_METABOLISM18",0.0422634537163814,0.0284225395269028,0.0960408519333705,3.19237535115356,23.1318683735771,17.3442048671007,5.09849952751831e-06,1.35990680360182e-05,0.0043240684041232,5.35909596003185e-05,1.61611720686274e-05,1.89875524516086e-05,1.89875524516086e-05,5.30478159714649e-06,1.50991697637207e-05,0.00141107833576437,0,0,0,0.00469713141526275,"HALLMARK_XENOBIOTIC_METABOLISM","kendall_tau","HN22","HN28",0.00199450495535926 "HALLMARK_WNT_BETA_CATENIN_SIGNALING18",0.0362668424128643,0.0348460383558539,0.103157503334469,0.319963527068935,30.0472105452006,16.0987261375063,6.52784107414752e-06,1.30903661319674e-05,0.00442924454124119,9.90738502740784e-05,4.68619042932033e-05,0.000108512123997998,0.000108512123997998,4.85590136036534e-06,1.7905458018159e-05,0.748995979423207,0,0,0,0.00642577332261392,"HALLMARK_WNT_BETA_CATENIN_SIGNALING","kendall_tau","HN22","HN28",0.782255125934007 "HALLMARK_KRAS_SIGNALING_DN18",0.054607160153672,0.0437108519277465,0.12552569976504,2.24534997130941,26.4451507761192,18.2538935176033,6.97852727309232e-06,1.64714599390335e-05,0.00484251868474721,7.35034054969094e-05,4.80536659235621e-05,4.9879186433276e-05,4.9879186433276e-05,7.09163227313739e-06,1.99887645400608e-05,0.0247456743936769,0,0,0,0.00624591087826034,"HALLMARK_KRAS_SIGNALING_DN","kendall_tau","HN22","HN28",0.0319088959286887 "HALLMARK_COAGULATION18",0.0407437596429873,0.0327961859481197,0.11027882704779,1.7346685082711,28.1360172212272,15.8640951317757,3.84145204324344e-06,1.70496934511494e-05,0.00457068326340743,6.59325832147537e-05,4.99921399605991e-05,-1.16899633288356e-05,-1.16899633288356e-05,6.00776779504611e-06,2.37549340681379e-05,0.0827995373188037,0,0,0,0.00561812296888839,"HALLMARK_COAGULATION","kendall_tau","HN22","HN28",0.101323887499389 "HALLMARK_HEDGEHOG_SIGNALING18",0.045164386791606,0.026923549907768,0.107149143732098,4.54873212311568,20.1949165590318,23.7404065135302,6.62058571830363e-06,9.36025669110676e-06,0.00399760458392403,0.000194659126967813,1.65502913522554e-05,-1.96561817737383e-05,-1.96561817737383e-05,9.32075433635893e-06,1.13195654598322e-05,5.39700906254659e-06,0,0,0,0.0052228215603372,"HALLMARK_HEDGEHOG_SIGNALING","kendall_tau","HN22","HN28",9.26552212781721e-06 "CELL_CYCLE18",0.0448368027231437,0.0310071446169007,0.0962513224062722,3.75664292463766,22.0384131383132,16.9928872019723,3.78897496774541e-06,9.66363856839999e-06,0.00366778046455147,0.00012514020167167,3.16893038031316e-05,8.05709292958385e-06,8.05709292958385e-06,5.3426564968824e-06,1.46417545459107e-05,0.000172207937751745,0,0,0,0.00431933029614434,"CELL_CYCLE","kendall_tau","HN22","HN28",0.000261649269762341 "PEMT18",0.0597734070515726,0.0458758314855876,0.15451628397109,2.09106793770579,26.3204568311695,18.4130627949906,1.42039774073158e-05,2.98674874667844e-05,0.0066386342627155,0.00011415861333661,0.000128007278373792,0.0001614939352691,0.0001614939352691,1.28570546545283e-05,3.4712167383195e-05,0.0365219743440992,0,0,0,0.00874564726058201,"PEMT","kendall_tau","HN22","HN28",0.046633921638068 "EPI_DIFF118",0.0533030921665019,0.0438669623059867,0.139315661223839,1.32436490038593,23.180956353399,14.9624119704169,1.84612582303584e-05,3.22046889774485e-05,0.00711800163021946,0.000186353426211663,0.000128408816363945,0.000282371642914155,0.000282371642914155,1.3667691963514e-05,4.05946023414973e-05,0.185381885745087,0,0,0,0.00903584551309716,"EPI_DIFF1","kendall_tau","HN22","HN28",0.214680660975333 "EPI_DIFF218",0.0587074275010466,0.0392707563439271,0.134779067576772,3.51073491237872,25.353180108741,21.094456781542,1.28469232228055e-05,1.77042920184445e-05,0.00552731537378228,0.000103126784843539,2.51204280651458e-05,0.000161345094261932,0.000161345094261932,8.90286371458259e-06,2.03996119408024e-05,0.00044686977902364,0,0,0,0.00725246494609108,"EPI_DIFF2","kendall_tau","HN22","HN28",0.000656078477068415 "STRESS18",0.0473715758738033,0.0341771307466914,0.142049463199195,2.25843932241113,31.3353210417426,19.7448924206917,1.08365364877628e-05,2.31957521030005e-05,0.00583371996163369,0.000121679714682806,4.38302295842179e-05,0.000115994271536107,0.000115994271536107,9.02911797794431e-06,2.97476810288559e-05,0.0239182835029161,0,0,0,0.00823025405654155,"STRESS","kendall_tau","HN22","HN28",0.0309097817576147 "HYPOXIA18",0.0503883995450113,0.0379901554117582,0.129090195892527,2.32345536214676,26.2940119780619,17.0094192967627,8.46211898902023e-06,1.99120921433109e-05,0.00532674489086263,9.22791750002476e-05,8.25470386632311e-05,7.11619500541804e-05,7.11619500541804e-05,8.8589183263945e-06,2.85852187355141e-05,0.0201547029748554,0,0,0,0.00693139356309895,"HYPOXIA","kendall_tau","HN22","HN28",0.0261899786722983 "HALLMARK_PANCREAS_BETA_CELLS19",0.0480557469590371,0.0771979577949727,0.0731386409612924,-7.71938104231327,6.24975765419209,-2.21018509736623,7.65496427001669e-06,6.49717421781423e-06,0.00376193281277469,4.97947070371907e-05,0.000711367420237728,7.98282348727984e-05,7.98282348727984e-05,1.60075293564172e-05,3.2732506054138e-06,1.17683640610267e-14,4.11090050889129e-10,0.0270923188151901,3.530509218308e-14,0.00533700181383111,"HALLMARK_PANCREAS_BETA_CELLS","kendall_tau","HN22","HN5",4.27148028881708e-14 "HALLMARK_MYOGENESIS19",0.0420113457187662,0.0654073624567887,0.0642033603361093,-6.72232792351779,5.99431199230099,-0.704164989274688,5.49433243928768e-06,6.51846511175364e-06,0.00346594829030113,8.62868848520203e-05,0.000678634689346209,8.15798729767283e-05,8.15798729767283e-05,1.36061276681251e-05,2.82351715776087e-06,1.78843606590817e-11,2.0434871572661e-09,0.481330031398715,5.36530819772452e-11,0.0049951382566272,"HALLMARK_MYOGENESIS","kendall_tau","HN22","HN5",4.90256599885317e-11 "HALLMARK_IL2_STAT5_SIGNALING19",0.0368007893047348,0.0517924539022566,0.0527317384615288,-5.27841165441227,5.41730686627425,0.612146061007736,4.32358195375476e-06,3.64306779660824e-06,0.00282252542067614,8.2517923764079e-05,0.000388856842327059,6.76166466237369e-05,6.76166466237369e-05,8.54801489417265e-06,2.25442167722344e-06,1.30308464685314e-07,6.0503448251481e-08,0.540441124944904,1.81510344754443e-07,0.00391024054214345,"HALLMARK_IL2_STAT5_SIGNALING","kendall_tau","HN22","HN5",2.62852065986156e-07 "HALLMARK_ESTROGEN_RESPONSE_EARLY19",0.0417217049497595,0.0648329617331342,0.0644473527804582,-6.39221729141316,5.92065004685454,-0.195362181184089,7.60978419487775e-06,5.36227683191947e-06,0.00360167475305547,0.000144831064326324,0.000722059441724254,0.000147880446255644,0.000147880446255644,1.46330872525145e-05,3.79594866547659e-06,1.63497437810634e-10,3.20671578180054e-09,0.845109421173775,4.90492313431901e-10,0.00538795627143332,"HALLMARK_ESTROGEN_RESPONSE_EARLY","kendall_tau","HN22","HN5",4.10839715524156e-10 "HALLMARK_BILE_ACID_METABOLISM19",0.0435580324663076,0.0620953382147412,0.0625118946328027,-6.59302698192533,5.92171568206992,0.255895432148694,4.67939272334531e-06,3.12600128117243e-06,0.00279381352357628,6.32764610468128e-05,0.000462262165191667,5.84836610657462e-05,5.84836610657462e-05,1.01447256447456e-05,2.5498579484392e-06,4.30948610130599e-11,3.18600101856248e-09,0.798031581842113,1.2928458303918e-10,0.00413758878538024,"HALLMARK_BILE_ACID_METABOLISM","kendall_tau","HN22","HN5",1.13377084007513e-10 "HALLMARK_MITOTIC_SPINDLE19",0.0753491428084734,0.0868388982451834,0.0985308361700639,-2.25052963286797,4.16303037486501,2.73379467251906,1.56059687047878e-05,1.03586933251022e-05,0.00509555316230633,0.000557974603611426,0.000999552900424678,0.000128095069795717,0.000128095069795717,3.09078142945595e-05,1.8191158629502e-05,0.0244153446105162,3.14051570990959e-05,0.0062609073327442,9.42154712972876e-05,0.00622310516024233,"HALLMARK_MITOTIC_SPINDLE","kendall_tau","HN22","HN5",0.031517503031797 "HALLMARK_INFLAMMATORY_RESPONSE19",0.031602112600324,0.0567048611476995,0.0530964604647329,-8.40407856446761,6.55377891791409,-2.79260177234082,2.607723170317e-06,6.21427940401712e-06,0.00297018561277475,3.50663420173084e-05,0.000610384692964599,4.03489266842057e-05,4.03489266842057e-05,1.06563511681321e-05,1.56959637863913e-06,0,5.60989033004944e-11,0.00522860170034933,0,0.00453309155048764,"HALLMARK_INFLAMMATORY_RESPONSE","kendall_tau","HN22","HN5",0 "HALLMARK_ESTROGEN_RESPONSE_LATE19",0.0485605638218152,0.0690578628102066,0.0713699439124634,-5.08477961249728,5.40313290040911,0.963960197228254,1.00310686637637e-05,6.11876814022956e-06,0.00401868595488541,0.000197338309926653,0.000786174136509528,0.000169639516805644,0.000169639516805644,1.77211474930384e-05,5.65291456273249e-06,3.68053184596207e-07,6.54869019012239e-08,0.33506588160342,1.96460705703672e-07,0.00567451846476696,"HALLMARK_ESTROGEN_RESPONSE_LATE","kendall_tau","HN22","HN5",7.13065148410443e-07 "HALLMARK_ADIPOGENESIS19",0.0330938335475744,0.0564948200342657,0.0543210592421322,-8.63104555269982,6.35765906314271,-1.46513335552502,3.07107281222877e-06,4.17984410437868e-06,0.00269275266532362,4.67934196606242e-05,0.000608762956161456,4.46974790790512e-05,4.46974790790512e-05,1.10478728256853e-05,2.10124909759893e-06,0,2.04851469121081e-10,0.142884537828192,0,0.0044538436452547,"HALLMARK_ADIPOGENESIS","kendall_tau","HN22","HN5",0 "HALLMARK_P53_PATHWAY19",0.0454389451888412,0.0727310000931841,0.0719629188208697,-7.41269182334357,6.2114248032319,-0.377196343138075,7.16668283262745e-06,6.28897451580594e-06,0.00366819538035168,0.000119525972586389,0.000919448023508287,0.000111850236938924,0.000111850236938924,1.81345357689303e-05,4.04647837575981e-06,1.23678844943242e-13,5.25063104106493e-10,0.706027697689962,3.71036534829727e-13,0.00573796097124376,"HALLMARK_P53_PATHWAY","kendall_tau","HN22","HN5",4.13199777424014e-13 "HALLMARK_HEME_METABOLISM19",0.0378211023784354,0.0592759591717066,0.0585116003950519,-7.63053767939655,6.14996858151974,-0.454218517473801,3.77077605255961e-06,4.03493537264672e-06,0.00279387033077885,6.13741103182466e-05,0.000590315519514752,5.58858549497623e-05,5.58858549497623e-05,1.12186881417408e-05,2.73181476893353e-06,2.33146835171283e-14,7.74982966689208e-10,0.649671556331061,6.99440505513849e-14,0.00444353474409877,"HALLMARK_HEME_METABOLISM","kendall_tau","HN22","HN5",8.18449785556503e-14 "HALLMARK_CHOLESTEROL_HOMEOSTASIS19",0.0424846473959409,0.0651818153351582,0.0656785793110616,-6.72904102867889,5.90739003941786,0.2472561184167,5.44442682290112e-06,5.83281501051664e-06,0.00335816048357099,0.000113437193754113,0.000780353281502328,8.11951834869657e-05,8.11951834869657e-05,1.5315494589839e-05,3.93651057341385e-06,1.70785607878088e-11,3.47570172642975e-09,0.80471001698073,5.12356823634263e-11,0.00514450340851696,"HALLMARK_CHOLESTEROL_HOMEOSTASIS","kendall_tau","HN22","HN5",4.69261389870634e-11 "HALLMARK_NOTCH_SIGNALING19",0.0303404303219374,0.0555105703155775,0.0539122967434446,-8.72463115199086,6.25678881429652,-0.84553799175364,3.99804513530041e-06,4.22490151981498e-06,0.00286756807331847,4.31634667299621e-05,0.000742299628312883,4.00587037569899e-05,4.00587037569899e-05,1.40933512225031e-05,3.47302442036512e-06,0,3.92984977892752e-10,0.397810530015091,0,0.00481514472259091,"HALLMARK_NOTCH_SIGNALING","kendall_tau","HN22","HN5",0 "HALLMARK_ALLOGRAFT_REJECTION19",0.0340806200565269,0.0463594283966109,0.0472543176299934,-5.76105898325925,5.98899868752618,0.624205053785519,1.8746436659711e-06,2.56799086294755e-06,0.00210775580391056,5.14897533241705e-05,0.000225880299083759,2.79715683107261e-05,2.79715683107261e-05,4.73845763266019e-06,1.95534156458949e-06,8.35878211091767e-09,2.11136863548234e-09,0.532492928314447,6.33410590644701e-09,0.0028851034171946,"HALLMARK_ALLOGRAFT_REJECTION","kendall_tau","HN22","HN5",1.84426412053268e-08 "HALLMARK_INTERFERON_GAMMA_RESPONSE19",0.0290458811082174,0.0575941779952491,0.0533431714267951,-10.1295189597258,6.6032273074318,-2.88067339775422,2.5794971410895e-06,5.2634699967264e-06,0.00280052979591646,3.02731252824254e-05,0.000808044407674538,4.32785107479686e-05,4.32785107479686e-05,1.34395175884414e-05,2.07768724769134e-06,0,4.02302635649221e-11,0.00396826607076939,0,0.00499954229091485,"HALLMARK_INTERFERON_GAMMA_RESPONSE","kendall_tau","HN22","HN5",0 "HALLMARK_ANDROGEN_RESPONSE19",0.0374515414794577,0.0549615558570782,0.0557874999841637,-6.08054448209776,6.04008975153967,0.482681339245524,4.91528865310397e-06,3.27726071299114e-06,0.00286226297989809,9.70717655916012e-05,0.000440418404184595,9.48695952046408e-05,9.48695952046408e-05,9.11553283694448e-06,2.82806235315627e-06,1.19775123152976e-09,1.54028523269290e-09,0.629322015087374,3.59325369458929e-09,0.00423794977473295,"HALLMARK_ANDROGEN_RESPONSE","kendall_tau","HN22","HN5",2.82842459493776e-09 "HALLMARK_TNFA_SIGNALING_VIA_NFKB19",0.0380961279836012,0.0661883137987541,0.0627815075628992,-7.87919282468684,6.39437473227695,-2.09943814841745,5.35121916971442e-06,7.26059709165276e-06,0.00355131190707986,8.69732236773021e-05,0.000812697338380801,0.000101404750222518,0.000101404750222518,1.48033345834934e-05,2.53322941739092e-06,3.33066907387547e-15,1.61205715443202e-10,0.0357782947982159,9.99200722162641e-15,0.00545026820122821,"HALLMARK_TNFA_SIGNALING_VIA_NFKB","kendall_tau","HN22","HN5",1.275852387908e-14 "HALLMARK_PEROXISOME19",0.0377547296106296,0.0575408956291522,0.058528642582957,-7.63646153591139,6.13129090998137,0.505355907608825,3.7911824798885e-06,2.82216242884905e-06,0.00257164245351828,7.33557934676347e-05,0.000582875150412669,5.13927629102245e-05,5.13927629102245e-05,1.13797590008341e-05,3.72029327585076e-06,2.24265050974282e-14,8.71688499159973e-10,0.613308881844894,6.72795152922845e-14,0.00431720965567029,"HALLMARK_PEROXISOME","kendall_tau","HN22","HN5",7.91999098936202e-14 "HALLMARK_INTERFERON_ALPHA_RESPONSE19",0.0372582289083985,0.0781150713643364,0.0709478107923324,-10.1676784441652,6.64959337888223,-3.98805732474723,4.39515120262435e-06,1.1651631241234e-05,0.00400584353711654,5.12273759478606e-05,0.00156604872046564,7.82710884364652e-05,7.82710884364652e-05,2.55685338970863e-05,3.12985929535525e-06,0,2.93904900416919e-11,6.66165686820097e-05,0,0.00699040552308468,"HALLMARK_INTERFERON_ALPHA_RESPONSE","kendall_tau","HN22","HN5",0 "HALLMARK_TGF_BETA_SIGNALING19",0.0323103764477756,0.0611446294352518,0.0569446339817569,-8.46057781211493,6.18041695535346,-2.65938636565825,3.8828206755302e-06,7.63212976520771e-06,0.00339336859782988,4.78410702801726e-05,0.000912944664269569,6.31839739137119e-05,6.31839739137119e-05,1.57870551854983e-05,2.39422004325601e-06,0,6.3932525939947e-10,0.00782831325655753,0,0.0054169707945414,"HALLMARK_TGF_BETA_SIGNALING","kendall_tau","HN22","HN5",0 "HALLMARK_FATTY_ACID_METABOLISM19",0.032447008842743,0.0570226495369786,0.0549800175689704,-8.98467900843024,6.34709472678944,-1.27254997612246,3.4455372688468e-06,3.93623639481641e-06,0.00271694196913795,4.98567555740942e-05,0.00069483644210895,5.15202986358333e-05,5.15202986358333e-05,1.25034200231458e-05,2.47650242012721e-06,0,2.19418927471793e-10,0.20317777925643,0,0.0047081539369166,"HALLMARK_FATTY_ACID_METABOLISM","kendall_tau","HN22","HN5",0 "HALLMARK_UNFOLDED_PROTEIN_RESPONSE19",0.0517290058487894,0.0826319874827337,0.0797897214553429,-7.58096548010657,5.88520195486331,-1.27384585848737,9.49810345496811e-06,7.0188624738375e-06,0.00406410702723312,0.00012495802384733,0.00115597950211105,0.000153737721715373,0.000153737721715373,2.2633941775458e-05,4.87846764917867e-06,3.41948691584548e-14,3.9756822278747e-09,0.202718049271678,1.02584607475364e-13,0.00642694484298325,"HALLMARK_UNFOLDED_PROTEIN_RESPONSE","kendall_tau","HN22","HN5",1.17582357106266e-13 "HALLMARK_MTORC1_SIGNALING19",0.0474205881995077,0.061613676705554,0.0657358156642992,-4.45253756015965,5.29963584077094,1.84321360415381,6.13279047637927e-06,3.92826069551633e-06,0.00317191600959035,0.000172446973616162,0.00048882524468999,9.02703480111745e-05,9.02703480111745e-05,1.1843526470785e-05,4.90142685306188e-06,8.48613897885819e-06,1.16033878949651e-07,0.0652978293926174,3.48101636848952e-07,0.00440313854795946,"HALLMARK_MTORC1_SIGNALING","kendall_tau","HN22","HN5",1.43592797685428e-05 "HALLMARK_UV_RESPONSE_UP19",0.0407477310721495,0.0611758968042069,0.0627027718339929,-6.59835531197649,5.79598112830129,0.746691783366494,4.98886132111835e-06,4.49603344891963e-06,0.0030797556347928,0.000110812615195116,0.000733418325814411,7.78806027717052e-05,7.78806027717052e-05,1.42487665571864e-05,4.08142432011499e-06,4.15742995585333e-11,6.79229028577311e-09,0.455249630685458,1.247228986756e-10,0.004901214209612,"HALLMARK_UV_RESPONSE_UP","kendall_tau","HN22","HN5",1.09868261305248e-10 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