The PDFset includes:

• Fig. S1. TNFα depletion in CBA/J mice results in fungal persistence and dysregulated immunity during C. neo infection.
• Fig. S2. Schematic of BMDC experiments and testing model.
• Fig. S3. TNFRI and TNFRII are both required for optimal DC1 programming.
• Fig. S4. TNFα results in sustained DC1 profile at the protein level in pulmonary DCs during C. neo infection.
• Fig. S5. MLL1 is uniquely induced in TNFα-programmed DC1.
• Fig. S6. DC1 from control C. neo–infected mice epigenetically resemble TNFα-programmed DC1.
• Fig. S7. Assessment of total and myeloid precursor populations in the BM during C. neo infection.

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Other Supplementary Material for this manuscript includes the following:

• Supplemental file 1. C.neo H3K4me3 Peaks.xlsx
• Supplemental file 2. 52D Infected Unique and Shared Peaks.xlsx
• Supplemental file 3. 52D Infected Gene Ontology.xlsx