GO results of EGFR-MUT enrichment,,,,,, Analysis Type:,PANTHER Overrepresentation Test (Released 20190606),,,,, Annotation Version and Release Date:,GO Ontology database Released 2019-02-02,,,,, Analyzed List:,upload_1 (Homo sapiens),,,,, Reference List:,Homo sapiens (all genes in database),,,,, Test Type:,FISHER,,,,, Correction:,BONFERRONI,,,,, Bonferroni count:,8795,,,,, GO biological process complete,Homo sapiens - REFLIST (20996),upload_1 (1624),upload_1 (expected),upload_1 (over/under),upload_1 (fold Enrichment),upload_1 (P-value) proximal/distal pattern formation (GO:0009954),33,15,2.55,+,5.88,6.50E-03 collagen fibril organization (GO:0030199),46,18,3.56,+,5.06,3.06E-03 T cell costimulation (GO:0031295),53,18,4.1,+,4.39,1.63E-02 interferon-gamma-mediated signaling pathway (GO:0060333),71,24,5.49,+,4.37,3.55E-04 lymphocyte costimulation (GO:0031294),54,18,4.18,+,4.31,2.03E-02 embryonic skeletal system morphogenesis (GO:0048704),96,32,7.43,+,4.31,2.74E-06 cilium movement (GO:0003341),55,18,4.25,+,4.23,2.51E-02 embryonic skeletal system development (GO:0048706),128,41,9.9,+,4.14,2.62E-08 negative regulation of viral life cycle (GO:1903901),83,22,6.42,+,3.43,3.89E-02 cellular response to interferon-gamma (GO:0071346),160,39,12.38,+,3.15,6.90E-05 response to interferon-gamma (GO:0034341),182,44,14.08,+,3.13,9.60E-06 anterior/posterior pattern specification (GO:0009952),209,50,16.17,+,3.09,9.78E-07 extracellular matrix organization (GO:0030198),335,80,25.91,+,3.09,2.73E-12 skeletal system morphogenesis (GO:0048705),241,56,18.64,+,3,1.99E-07 extracellular structure organization (GO:0043062),381,88,29.47,+,2.99,4.98E-13 cartilage development (GO:0051216),175,39,13.54,+,2.88,5.49E-04 embryonic limb morphogenesis (GO:0030326),126,28,9.75,+,2.87,4.00E-02 embryonic appendage morphogenesis (GO:0035113),126,28,9.75,+,2.87,4.00E-02 positive regulation of leukocyte cell-cell adhesion (GO:1903039),217,47,16.78,+,2.8,7.73E-05 positive regulation of T cell activation (GO:0050870),204,44,15.78,+,2.79,2.59E-04 positive regulation of lymphocyte proliferation (GO:0050671),135,29,10.44,+,2.78,4.82E-02 positive regulation of leukocyte proliferation (GO:0070665),140,30,10.83,+,2.77,3.49E-02 regulation of T cell proliferation (GO:0042129),160,34,12.38,+,2.75,1.40E-02 embryonic organ morphogenesis (GO:0048562),289,61,22.35,+,2.73,8.06E-07 limb morphogenesis (GO:0035108),148,31,11.45,+,2.71,4.98E-02 appendage morphogenesis (GO:0035107),148,31,11.45,+,2.71,4.98E-02 skeletal system development (GO:0001501),495,101,38.29,+,2.64,3.54E-12 regionalization (GO:0003002),324,66,25.06,+,2.63,5.44E-07 regulation of leukocyte cell-cell adhesion (GO:1903037),295,60,22.82,+,2.63,4.54E-06 limb development (GO:0060173),178,36,13.77,+,2.61,1.38E-02 appendage development (GO:0048736),178,36,13.77,+,2.61,1.38E-02 regulation of lymphocyte proliferation (GO:0050670),214,42,16.55,+,2.54,4.44E-03 positive regulation of cell-cell adhesion (GO:0022409),255,50,19.72,+,2.54,3.25E-04 regulation of mononuclear cell proliferation (GO:0032944),215,42,16.63,+,2.53,4.79E-03 regulation of T cell activation (GO:0050863),314,61,24.29,+,2.51,1.54E-05 regulation of leukocyte proliferation (GO:0070663),224,43,17.33,+,2.48,4.80E-03 connective tissue development (GO:0061448),226,43,17.48,+,2.46,5.77E-03 T cell activation (GO:0042110),226,43,17.48,+,2.46,5.77E-03 pattern specification process (GO:0007389),422,80,32.64,+,2.45,1.43E-07 embryonic organ development (GO:0048568),425,80,32.87,+,2.43,1.74E-07 embryonic morphogenesis (GO:0048598),560,104,43.31,+,2.4,2.99E-10 positive regulation of cell adhesion (GO:0045785),404,74,31.25,+,2.37,3.91E-06 angiogenesis (GO:0001525),315,56,24.36,+,2.3,1.10E-03 regulation of angiogenesis (GO:0045765),288,51,22.28,+,2.29,5.41E-03 negative regulation of peptidase activity (GO:0010466),257,45,19.88,+,2.26,2.49E-02 regulation of cell-cell adhesion (GO:0022407),391,68,30.24,+,2.25,1.13E-04 blood vessel morphogenesis (GO:0048514),404,70,31.25,+,2.24,6.87E-05 ossification (GO:0001503),254,44,19.65,+,2.24,3.98E-02 regulation of vasculature development (GO:1901342),318,55,24.6,+,2.24,3.70E-03 lymphocyte activation (GO:0046649),372,64,28.77,+,2.22,4.49E-04 inflammatory response (GO:0006954),485,83,37.51,+,2.21,4.76E-06 animal organ morphogenesis (GO:0009887),930,154,71.93,+,2.14,1.75E-12 cytokine-mediated signaling pathway (GO:0019221),661,108,51.13,+,2.11,1.59E-07 response to lipopolysaccharide (GO:0032496),313,51,24.21,+,2.11,4.10E-02 response to molecule of bacterial origin (GO:0002237),327,53,25.29,+,2.1,2.66E-02 regulation of cell adhesion (GO:0030155),671,107,51.9,+,2.06,5.90E-07 blood vessel development (GO:0001568),486,77,37.59,+,2.05,4.31E-04 reproductive structure development (GO:0048608),421,66,32.56,+,2.03,6.42E-03 reproductive system development (GO:0061458),425,66,32.87,+,2.01,7.31E-03 vasculature development (GO:0001944),509,79,39.37,+,2.01,5.55E-04 embryo development (GO:0009790),948,147,73.33,+,2,9.93E-10 tube morphogenesis (GO:0035239),645,100,49.89,+,2,1.10E-05 negative regulation of immune system process (GO:0002683),440,68,34.03,+,2,7.00E-03 cardiovascular system development (GO:0072358),519,80,40.14,+,1.99,7.02E-04 chordate embryonic development (GO:0043009),610,94,47.18,+,1.99,4.12E-05 gland development (GO:0048732),417,63,32.25,+,1.95,3.41E-02 tube development (GO:0035295),837,126,64.74,+,1.95,3.88E-07 innate immune response (GO:0045087),752,113,58.17,+,1.94,3.73E-06 morphogenesis of an epithelium (GO:0002009),421,63,32.56,+,1.93,3.86E-02 embryo development ending in birth or egg hatching (GO:0009792),630,94,48.73,+,1.93,1.67E-04 defense response (GO:0006952),1320,196,102.1,+,1.92,2.36E-12 immune system development (GO:0002520),636,94,49.19,+,1.91,2.82E-04 tissue morphogenesis (GO:0048729),555,82,42.93,+,1.91,2.69E-03 response to cytokine (GO:0034097),1078,159,83.38,+,1.91,3.02E-09 cellular response to cytokine stimulus (GO:0071345),990,146,76.57,+,1.91,3.94E-08 hematopoietic or lymphoid organ development (GO:0048534),601,88,46.49,+,1.89,1.03E-03 positive regulation of cell migration (GO:0030335),487,71,37.67,+,1.88,2.28E-02 circulatory system development (GO:0072359),852,124,65.9,+,1.88,3.10E-06 positive regulation of cell motility (GO:2000147),509,73,39.37,+,1.85,2.55E-02 cell population proliferation (GO:0008283),663,95,51.28,+,1.85,7.99E-04 hemopoiesis (GO:0030097),552,79,42.7,+,1.85,1.25E-02 regulation of cytokine production (GO:0001817),685,98,52.98,+,1.85,5.62E-04 positive regulation of locomotion (GO:0040017),541,77,41.85,+,1.84,2.18E-02 anatomical structure formation involved in morphogenesis (GO:0048646),879,123,67.99,+,1.81,3.67E-05 response to bacterium (GO:0009617),681,95,52.67,+,1.8,2.46E-03 anatomical structure morphogenesis (GO:0009653),2102,293,162.59,+,1.8,5.30E-17 response to other organism (GO:0051707),957,133,74.02,+,1.8,1.13E-05 localization of cell (GO:0051674),1045,145,80.83,+,1.79,1.96E-06 cell motility (GO:0048870),1045,145,80.83,+,1.79,1.96E-06 response to external biotic stimulus (GO:0043207),959,133,74.18,+,1.79,1.19E-05 biological adhesion (GO:0022610),925,128,71.55,+,1.79,2.85E-05 cell adhesion (GO:0007155),919,127,71.08,+,1.79,3.67E-05 cell activation (GO:0001775),1048,144,81.06,+,1.78,4.31E-06 positive regulation of cell population proliferation (GO:0008284),934,128,72.24,+,1.77,4.83E-05 response to biotic stimulus (GO:0009607),985,134,76.19,+,1.76,3.82E-05 cell migration (GO:0016477),935,126,72.32,+,1.74,1.48E-04 negative regulation of developmental process (GO:0051093),933,125,72.17,+,1.73,2.75E-04 negative regulation of cell population proliferation (GO:0008285),683,91,52.83,+,1.72,3.03E-02 regulation of cell population proliferation (GO:0042127),1616,215,124.99,+,1.72,2.01E-09 leukocyte activation (GO:0045321),902,120,69.77,+,1.72,6.85E-04 locomotion (GO:0040011),1279,169,98.93,+,1.71,1.75E-06 regulation of cell migration (GO:0030334),827,109,63.97,+,1.7,4.63E-03 tissue development (GO:0009888),1730,228,133.81,+,1.7,6.82E-10 regulation of cell motility (GO:2000145),888,116,68.69,+,1.69,2.95E-03 regulation of locomotion (GO:0040012),963,124,74.49,+,1.66,2.25E-03 immune response (GO:0006955),1827,234,141.31,+,1.66,4.93E-09 positive regulation of developmental process (GO:0051094),1351,173,104.5,+,1.66,9.16E-06 negative regulation of multicellular organismal process (GO:0051241),1180,151,91.27,+,1.65,1.24E-04 regulation of cellular component movement (GO:0051270),969,122,74.95,+,1.63,8.46E-03 positive regulation of cell differentiation (GO:0045597),957,120,74.02,+,1.62,1.35E-02 animal organ development (GO:0048513),3138,392,242.72,+,1.62,1.32E-16 epithelium development (GO:0060429),1091,135,84.39,+,1.6,4.31E-03 movement of cell or subcellular component (GO:0006928),1511,186,116.87,+,1.59,3.21E-05 positive regulation of immune system process (GO:0002684),1130,139,87.4,+,1.59,3.73E-03 immune system process (GO:0002376),2740,337,211.93,+,1.59,1.50E-12 regulation of immune system process (GO:0002682),1629,200,126,+,1.59,8.08E-06 positive regulation of multicellular organismal process (GO:0051240),1720,210,133.04,+,1.58,4.67E-06 regulation of multicellular organismal development (GO:2000026),2014,245,155.78,+,1.57,1.89E-07 immune effector process (GO:0002252),1072,130,82.92,+,1.57,1.97E-02 response to external stimulus (GO:0009605),2076,251,160.57,+,1.56,1.48E-07 regulation of developmental process (GO:0050793),2551,305,197.31,+,1.55,2.03E-09 cellular response to organic substance (GO:0071310),2306,275,178.36,+,1.54,5.24E-08 regulation of multicellular organismal process (GO:0051239),3091,367,239.08,+,1.54,6.65E-12 reproduction (GO:0000003),1430,168,110.61,+,1.52,3.90E-03 reproductive process (GO:0022414),1427,167,110.38,+,1.51,4.95E-03 response to organic substance (GO:0010033),2922,332,226.01,+,1.47,4.86E-08 response to oxygen-containing compound (GO:1901700),1521,172,117.65,+,1.46,2.15E-02 regulation of cell differentiation (GO:0045595),1795,202,138.84,+,1.45,3.74E-03 anatomical structure development (GO:0048856),5342,594,413.19,+,1.44,1.79E-17 system development (GO:0048731),4367,485,337.78,+,1.44,1.32E-12 negative regulation of response to stimulus (GO:0048585),1594,177,123.29,+,1.44,4.33E-02 multi-organism process (GO:0051704),2508,278,193.99,+,1.43,4.14E-05 cell surface receptor signaling pathway (GO:0007166),2441,270,188.81,+,1.43,8.98E-05 multicellular organism development (GO:0007275),4963,548,383.88,+,1.43,9.15E-15 regulation of cell death (GO:0010941),1677,185,129.71,+,1.43,3.64E-02 response to stress (GO:0006950),3484,384,269.48,+,1.42,2.79E-08 cellular response to chemical stimulus (GO:0070887),2825,311,218.51,+,1.42,7.61E-06 developmental process (GO:0032502),5686,619,439.8,+,1.41,1.37E-16 cell differentiation (GO:0030154),3642,379,281.7,+,1.35,3.68E-05 cellular developmental process (GO:0048869),3734,384,288.82,+,1.33,9.42E-05 multicellular organismal process (GO:0032501),6886,703,532.62,+,1.32,2.40E-13 regulation of response to stimulus (GO:0048583),4388,438,339.4,+,1.29,1.82E-04 regulation of signal transduction (GO:0009966),3278,327,253.55,+,1.29,2.88E-02 negative regulation of cellular process (GO:0048523),4648,463,359.51,+,1.29,7.00E-05 positive regulation of biological process (GO:0048518),6102,607,471.98,+,1.29,3.86E-08 regulation of signaling (GO:0023051),3674,363,284.18,+,1.28,1.51E-02 regulation of cell communication (GO:0010646),3634,359,281.08,+,1.28,1.91E-02 positive regulation of cellular process (GO:0048522),5342,524,413.19,+,1.27,2.89E-05 negative regulation of biological process (GO:0048519),5221,512,403.83,+,1.27,5.38E-05 response to chemical (GO:0042221),4391,423,339.64,+,1.25,1.72E-02 response to stimulus (GO:0050896),8349,786,645.78,+,1.22,1.22E-07 regulation of biological process (GO:0050789),11621,1000,898.86,+,1.11,9.35E-03 biological regulation (GO:0065007),12307,1054,951.92,+,1.11,5.55E-03 Unclassified (UNCLASSIFIED),3214,195,248.6,-,0.78,0.00E+00 RNA metabolic process (GO:0016070),1662,73,128.55,-,0.57,1.04E-03 intracellular transport (GO:0046907),1551,63,119.97,-,0.53,1.54E-04 gene expression (GO:0010467),2001,81,154.77,-,0.52,5.45E-07 intracellular protein transport (GO:0006886),989,37,76.5,-,0.48,1.04E-02 protein ubiquitination (GO:0016567),689,21,53.29,-,0.39,1.12E-02 protein modification by small protein conjugation or removal (GO:0070647),976,27,75.49,-,0.36,3.39E-06 protein modification by small protein conjugation (GO:0032446),766,21,59.25,-,0.35,2.68E-04 amide biosynthetic process (GO:0043604),534,14,41.3,-,0.34,1.96E-02 detection of stimulus involved in sensory perception (GO:0050906),538,12,41.61,-,0.29,2.07E-03 peptide biosynthetic process (GO:0043043),417,8,32.25,-,0.25,1.27E-02 sensory perception of chemical stimulus (GO:0007606),534,10,41.3,-,0.24,1.63E-04 detection of chemical stimulus (GO:0009593),518,9,40.07,-,0.22,1.44E-04 ncRNA metabolic process (GO:0034660),470,7,36.35,-,0.19,1.28E-04 mRNA metabolic process (GO:0016071),680,9,52.6,-,0.17,5.61E-09 sensory perception of smell (GO:0007608),462,6,35.73,-,0.17,3.15E-05 mRNA processing (GO:0006397),471,6,36.43,-,0.16,2.32E-05 RNA processing (GO:0006396),865,11,66.91,-,0.16,1.33E-12 translation (GO:0006412),394,5,30.48,-,0.16,3.88E-04 detection of chemical stimulus involved in sensory perception (GO:0050907),482,5,37.28,-,0.13,1.77E-06 RNA splicing (GO:0008380),391,4,30.24,-,0.13,8.88E-05 detection of chemical stimulus involved in sensory perception of smell (GO:0050911),432,4,33.41,-,0.12,6.97E-06 ribosome biogenesis (GO:0042254),290,2,22.43,-,0.09,1.29E-03 ribonucleoprotein complex biogenesis (GO:0022613),443,3,34.27,-,0.09,4.20E-07 ncRNA processing (GO:0034470),384,2,29.7,-,0.07,1.94E-06 rRNA processing (GO:0006364),206,1,15.93,-,0.06,4.40E-02 ribonucleoprotein complex assembly (GO:0022618),228,1,17.64,-,0.06,9.38E-03 ribonucleoprotein complex subunit organization (GO:0071826),242,1,18.72,-,0.05,4.46E-03 ,,,,,, GO results of EGFR-WT enrichment,,,,,, Analysis Type:,PANTHER Overrepresentation Test (Released 20190606),,,,, Annotation Version and Release Date:,GO Ontology database Released 2019-02-02,,,,, Analyzed List:,upload_1 (Homo sapiens),,,,, Reference List:,Homo sapiens (all genes in database),,,,, Test Type:,FISHER,,,,, Correction:,BONFERRONI,,,,, Bonferroni count:,8795,,,,, GO biological process complete,Homo sapiens - REFLIST (20996),upload_1 (659),upload_1 (expected),upload_1 (over/under),upload_1 (fold Enrichment),upload_1 (P-value) ionotropic glutamate receptor signaling pathway (GO:0035235),25,9,0.78,+,11.47,4.95E-03 glutamate receptor signaling pathway (GO:0007215),46,13,1.44,+,9,1.68E-04 renal tubule morphogenesis (GO:0061333),69,17,2.17,+,7.85,6.65E-06 nephron tubule morphogenesis (GO:0072078),65,16,2.04,+,7.84,2.12E-05 nephron epithelium morphogenesis (GO:0072088),67,16,2.1,+,7.61,3.09E-05 nephron morphogenesis (GO:0072028),68,16,2.13,+,7.5,3.71E-05 positive regulation of synapse assembly (GO:0051965),68,16,2.13,+,7.5,3.71E-05 renal tubule development (GO:0061326),82,19,2.57,+,7.38,1.64E-06 nephron tubule development (GO:0072080),78,18,2.45,+,7.35,5.23E-06 branching involved in ureteric bud morphogenesis (GO:0001658),45,10,1.41,+,7.08,4.75E-02 kidney morphogenesis (GO:0060993),84,18,2.64,+,6.83,1.46E-05 membrane depolarization (GO:0051899),52,11,1.63,+,6.74,2.45E-02 nephron epithelium development (GO:0072009),96,20,3.01,+,6.64,2.81E-06 ureteric bud morphogenesis (GO:0060675),54,11,1.69,+,6.49,3.37E-02 mesonephric tubule morphogenesis (GO:0072171),55,11,1.73,+,6.37,3.93E-02 regulation of glutamate receptor signaling pathway (GO:1900449),62,12,1.95,+,6.17,1.96E-02 regulation of synapse assembly (GO:0051963),109,21,3.42,+,6.14,3.56E-06 regulation of postsynaptic membrane potential (GO:0060078),106,20,3.33,+,6.01,1.28E-05 metanephros development (GO:0001656),83,15,2.61,+,5.76,2.35E-03 nephron development (GO:0072006),124,22,3.89,+,5.65,5.40E-06 memory (GO:0007613),118,20,3.7,+,5.4,6.48E-05 action potential (GO:0001508),95,16,2.98,+,5.37,2.21E-03 kidney epithelium development (GO:0072073),128,21,4.02,+,5.23,4.57E-05 multicellular organismal signaling (GO:0035637),134,21,4.21,+,4.99,9.37E-05 cardiac conduction (GO:0061337),91,14,2.86,+,4.9,3.20E-02 cerebellum development (GO:0021549),106,16,3.33,+,4.81,8.20E-03 metencephalon development (GO:0022037),115,17,3.61,+,4.71,4.89E-03 regulation of synaptic plasticity (GO:0048167),183,26,5.74,+,4.53,1.10E-05 regulation of cation channel activity (GO:2001257),173,23,5.43,+,4.24,3.01E-04 adult behavior (GO:0030534),151,20,4.74,+,4.22,2.47E-03 regulation of membrane potential (GO:0042391),425,56,13.34,+,4.2,5.31E-14 learning (GO:0007612),145,19,4.55,+,4.17,5.67E-03 synapse organization (GO:0050808),268,35,8.41,+,4.16,1.26E-07 learning or memory (GO:0007611),257,33,8.07,+,4.09,7.27E-07 hindbrain development (GO:0030902),154,19,4.83,+,3.93,1.29E-02 regulation of synapse organization (GO:0050807),221,27,6.94,+,3.89,9.96E-05 regulation of heart contraction (GO:0008016),243,29,7.63,+,3.8,4.62E-05 cognition (GO:0050890),298,35,9.35,+,3.74,1.77E-06 regulation of synapse structure or activity (GO:0050803),230,27,7.22,+,3.74,2.13E-04 cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742),257,29,8.07,+,3.6,1.43E-04 locomotory behavior (GO:0007626),201,22,6.31,+,3.49,1.22E-02 regulation of ion transmembrane transporter activity (GO:0032412),251,27,7.88,+,3.43,1.09E-03 behavior (GO:0007610),577,62,18.11,+,3.42,6.14E-12 neuron projection guidance (GO:0097485),257,27,8.07,+,3.35,1.68E-03 trans-synaptic signaling (GO:0099537),429,45,13.46,+,3.34,1.43E-07 synaptic signaling (GO:0099536),439,46,13.78,+,3.34,8.76E-08 regulation of transmembrane transporter activity (GO:0022898),258,27,8.1,+,3.33,1.80E-03 chemical synaptic transmission (GO:0007268),411,43,12.9,+,3.33,4.43E-07 anterograde trans-synaptic signaling (GO:0098916),411,43,12.9,+,3.33,4.43E-07 calcium ion transmembrane transport (GO:0070588),202,21,6.34,+,3.31,4.41E-02 regulation of blood circulation (GO:1903522),289,30,9.07,+,3.31,4.49E-04 regulation of transporter activity (GO:0032409),270,28,8.47,+,3.3,1.28E-03 axon guidance (GO:0007411),255,26,8,+,3.25,4.77E-03 modulation of chemical synaptic transmission (GO:0050804),438,44,13.75,+,3.2,8.73E-07 regulation of trans-synaptic signaling (GO:0099177),439,44,13.78,+,3.19,9.33E-07 calcium ion transport (GO:0006816),254,25,7.97,+,3.14,1.42E-02 kidney development (GO:0001822),266,26,8.35,+,3.11,9.91E-03 renal system development (GO:0072001),282,27,8.85,+,3.05,8.92E-03 regulation of system process (GO:0044057),584,55,18.33,+,3,3.76E-08 regulation of ion transmembrane transport (GO:0034765),471,44,14.78,+,2.98,7.17E-06 axonogenesis (GO:0007409),366,34,11.49,+,2.96,7.00E-04 neuron projection development (GO:0031175),659,61,20.68,+,2.95,4.70E-09 neuron differentiation (GO:0030182),992,90,31.14,+,2.89,2.37E-14 neuron projection morphogenesis (GO:0048812),475,43,14.91,+,2.88,2.68E-05 plasma membrane bounded cell projection morphogenesis (GO:0120039),479,43,15.03,+,2.86,3.38E-05 cell morphogenesis involved in neuron differentiation (GO:0048667),424,38,13.31,+,2.86,2.88E-04 neuron development (GO:0048666),804,72,25.24,+,2.85,1.47E-10 cell projection morphogenesis (GO:0048858),481,43,15.1,+,2.85,3.79E-05 regulation of nervous system development (GO:0051960),914,81,28.69,+,2.82,4.85E-12 urogenital system development (GO:0001655),317,28,9.95,+,2.81,2.42E-02 cell part morphogenesis (GO:0032990),502,44,15.76,+,2.79,4.32E-05 axon development (GO:0061564),401,35,12.59,+,2.78,1.82E-03 regulation of ion transport (GO:0043269),684,59,21.47,+,2.75,1.66E-07 generation of neurons (GO:0048699),1513,128,47.49,+,2.7,1.30E-19 positive regulation of nervous system development (GO:0051962),532,45,16.7,+,2.69,7.84E-05 regulation of neuron differentiation (GO:0045664),649,54,20.37,+,2.65,6.42E-06 neurogenesis (GO:0022008),1612,134,50.6,+,2.65,4.50E-20 forebrain development (GO:0030900),390,32,12.24,+,2.61,2.06E-02 regulation of transmembrane transport (GO:0034762),552,45,17.33,+,2.6,2.84E-04 cell-cell adhesion (GO:0098609),494,40,15.51,+,2.58,2.05E-03 inorganic ion transmembrane transport (GO:0098660),649,52,20.37,+,2.55,3.20E-05 regulation of neurogenesis (GO:0050767),807,64,25.33,+,2.53,9.07E-07 ion transmembrane transport (GO:0034220),905,70,28.41,+,2.46,2.18E-07 inorganic cation transmembrane transport (GO:0098662),564,43,17.7,+,2.43,3.50E-03 regulation of hormone levels (GO:0010817),526,40,16.51,+,2.42,1.04E-02 brain development (GO:0007420),733,55,23.01,+,2.39,1.40E-04 cell-cell signaling (GO:0007267),1093,82,34.31,+,2.39,2.02E-08 central nervous system development (GO:0007417),963,72,30.23,+,2.38,4.73E-07 nervous system development (GO:0007399),2324,173,72.94,+,2.37,2.26E-22 cation transmembrane transport (GO:0098655),618,46,19.4,+,2.37,2.01E-03 metal ion transport (GO:0030001),636,47,19.96,+,2.35,1.73E-03 head development (GO:0060322),779,57,24.45,+,2.33,1.19E-04 cell morphogenesis (GO:0000902),697,51,21.88,+,2.33,8.18E-04 chemotaxis (GO:0006935),539,39,16.92,+,2.31,3.19E-02 regulation of cell development (GO:0060284),928,67,29.13,+,2.3,9.71E-06 cellular component morphogenesis (GO:0032989),797,55,25.02,+,2.2,1.74E-03 cell adhesion (GO:0007155),919,58,28.84,+,2.01,1.14E-02 cell development (GO:0048468),1603,101,50.31,+,2.01,7.16E-07 ion transport (GO:0006811),1337,84,41.96,+,2,4.44E-05 transmembrane transport (GO:0055085),1291,81,40.52,+,2,7.49E-05 biological adhesion (GO:0022610),925,58,29.03,+,2,1.29E-02 plasma membrane bounded cell projection organization (GO:0120036),1082,66,33.96,+,1.94,7.37E-03 regulation of multicellular organismal development (GO:2000026),2014,122,63.21,+,1.93,5.73E-08 nervous system process (GO:0050877),1366,81,42.87,+,1.89,1.03E-03 regulation of transport (GO:0051049),1829,108,57.41,+,1.88,5.58E-06 cell projection organization (GO:0030030),1122,66,35.22,+,1.87,1.89E-02 system process (GO:0003008),1937,113,60.8,+,1.86,4.13E-06 regulation of multicellular organismal process (GO:0051239),3091,180,97.02,+,1.86,2.41E-12 positive regulation of developmental process (GO:0051094),1351,78,42.4,+,1.84,5.06E-03 anatomical structure morphogenesis (GO:0009653),2102,120,65.98,+,1.82,3.26E-06 regulation of cell differentiation (GO:0045595),1795,102,56.34,+,1.81,1.31E-04 positive regulation of multicellular organismal process (GO:0051240),1720,95,53.99,+,1.76,1.33E-03 cellular developmental process (GO:0048869),3734,205,117.2,+,1.75,3.21E-12 regulation of developmental process (GO:0050793),2551,140,80.07,+,1.75,1.16E-06 cell differentiation (GO:0030154),3642,199,114.31,+,1.74,2.16E-11 system development (GO:0048731),4367,235,137.07,+,1.71,5.91E-14 regulation of localization (GO:0032879),2702,145,84.81,+,1.71,2.21E-06 multicellular organism development (GO:0007275),4963,248,155.77,+,1.59,2.66E-11 regulation of biological quality (GO:0065008),4007,200,125.77,+,1.59,8.90E-08 anatomical structure development (GO:0048856),5342,266,167.67,+,1.59,1.93E-12 developmental process (GO:0032502),5686,280,178.47,+,1.57,5.49E-13 multicellular organismal process (GO:0032501),6886,332,216.13,+,1.54,4.62E-16 animal organ development (GO:0048513),3138,145,98.49,+,1.47,2.16E-02 regulation of cell communication (GO:0010646),3634,167,114.06,+,1.46,3.51E-03 regulation of signaling (GO:0023051),3674,168,115.32,+,1.46,3.96E-03 cell communication (GO:0007154),5401,243,169.52,+,1.43,4.85E-06 signaling (GO:0023052),5293,237,166.13,+,1.43,1.56E-05 regulation of biological process (GO:0050789),11621,429,364.75,+,1.18,5.32E-03 biological regulation (GO:0065007),12307,452,386.28,+,1.17,2.14E-03 Unclassified (UNCLASSIFIED),3214,68,100.88,-,0.67,0.00E+00 cellular nitrogen compound metabolic process (GO:0034641),3404,64,106.84,-,0.6,2.18E-02 nucleobase-containing compound metabolic process (GO:0006139),2770,46,86.94,-,0.53,5.93E-03 nucleic acid metabolic process (GO:0090304),2263,36,71.03,-,0.51,2.89E-02 immune response (GO:0006955),1827,24,57.34,-,0.42,5.19E-03