"GeneProgram Topic-Modeling Results from 773 cells, and 33088 nonzero-expression genes. The FPKM values of each gene are discretized into 4 levels." "Overall number of cells from each time pt- hesc_: 53, stage1_: 63, stage2_: 68, stage3_: 70, St4_3_: 87, stage4: 70, St5_3_: 73, stage5_: 64, stage6.2_: 82, stage6.7_: 76, stage6.14_: 67" --------------------------------------------- "EP #1: 773 cells, 1119 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 1, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 1, St5_3_: 1, stage5_: 1, stage6.2_: 1, stage6.7_: 1, stage6.14_: 1, " Top Genes: 3.978 MT-ATP6/ENSG00000198899.2 3.977 RPS27/ENSG00000177954.7 3.973 RPS19/ENSG00000105372.2 3.973 RPS11/ENSG00000142534.2 3.973 FTL/ENSG00000087086.9 3.972 RPL21/ENSG00000122026.6 3.972 EEF1A1/ENSG00000156508.13 3.971 RPL3/ENSG00000100316.11 3.97 RPL23/ENSG00000125691.8 3.969 RPS29/ENSG00000213741.4 3.969 MT-CO3/ENSG00000198938.2 3.968 RPL41/ENSG00000229117.4 3.968 MT-ATP8/ENSG00000228253.1 3.963 MT-ND4L/ENSG00000212907.2 3.963 RPS3/ENSG00000149273.10 3.962 MT-CYB/ENSG00000198727.2 3.961 RPL5/ENSG00000122406.8 3.961 RPS18/ENSG00000231500.2 3.96 MT-ND4/ENSG00000198886.2 3.96 MT-CO2/ENSG00000198712.1 3.958 RPL15/ENSG00000174748.14 3.954 ACTB/ENSG00000075624.9 3.954 MT-CO1/ENSG00000198804.2 3.953 RPL34/ENSG00000109475.12 3.952 RPL37A/ENSG00000197756.5 3.951 GNB2L1/ENSG00000204628.7 3.95 MYL6/ENSG00000092841.14 3.95 MT-ND1/ENSG00000198888.2 3.949 MT-ND2/ENSG00000198763.3 3.939 RPL18A/ENSG00000105640.8 3.938 RPL9/ENSG00000163682.11 3.937 RPL19/ENSG00000108298.5 3.935 RPL30/ENSG00000156482.6 3.934 UBB/ENSG00000170315.9 3.933 RPLP0/ENSG00000089157.11 3.932 RPS14/ENSG00000164587.7 3.932 SERF2/ENSG00000140264.15 3.932 GAPDH/ENSG00000111640.10 3.931 HSP90AB1/ENSG00000096384.15 3.93 MORF4L1/ENSG00000185787.10 3.929 RPL23A/ENSG00000198242.9 3.927 RPL35/ENSG00000136942.10 3.927 RPL13A/ENSG00000142541.12 3.926 SRP14/ENSG00000140319.6 3.925 H3F3B/ENSG00000132475.4 3.924 CALM2/ENSG00000143933.11 3.924 RPS6/ENSG00000137154.8 3.923 RP5-940J5.9/ENSG00000269968.1 3.92 RPS3A/ENSG00000145425.5 3.919 PPIA/ENSG00000196262.9 3.918 RPL35A/ENSG00000182899.10 3.917 RPL7/ENSG00000147604.9 3.916 NPM1/ENSG00000181163.9 3.912 ACTG1/ENSG00000184009.5 3.912 RPS23/ENSG00000186468.8 3.911 RPL36/ENSG00000130255.8 3.91 RPS27A/ENSG00000143947.8 3.904 RPL10/ENSG00000147403.12 3.902 RPL39/ENSG00000198918.7 3.901 COX6A1/ENSG00000111775.2 3.898 RPL27/ENSG00000131469.8 3.898 RPL4/ENSG00000174444.10 3.897 RPL32/ENSG00000144713.8 3.897 RPLP1/ENSG00000137818.7 3.897 MALAT1/ENSG00000251562.3 3.896 RPS28/ENSG00000233927.4 3.881 RPS13/ENSG00000110700.2 3.879 SKP1/ENSG00000113558.12 3.877 COX7C/ENSG00000127184.6 3.876 RPS25/ENSG00000118181.6 3.876 RPL8/ENSG00000161016.11 3.876 RPL12/ENSG00000197958.8 3.873 RPS15A/ENSG00000134419.11 3.871 COX4I1/ENSG00000131143.4 3.868 RPL38/ENSG00000172809.8 3.863 TPT1/ENSG00000133112.12 3.861 RPL31/ENSG00000071082.6 3.851 PFDN5/ENSG00000123349.9 3.848 RPL11/ENSG00000142676.8 3.844 RPS24/ENSG00000138326.14 3.837 EEF1G/ENSG00000254772.5 3.834 RPL24/ENSG00000114391.8 3.832 RPL17/ENSG00000265681.1 3.829 RPS20/ENSG00000008988.5 3.828 HSPA8/ENSG00000109971.9 3.828 RPL14/ENSG00000188846.9 3.827 RPL7A/ENSG00000148303.12 3.824 MT-ND5/ENSG00000198786.2 3.82 RPL27A/ENSG00000166441.8 3.816 RP11-138I1.4/ENSG00000265401.1 3.809 ATP5J2/ENSG00000241468.3 3.807 MT-ND6/ENSG00000198695.2 3.805 RPL29/ENSG00000162244.6 3.805 NDUFS5/ENSG00000168653.6 3.801 RPS8/ENSG00000142937.7 3.795 RPS21/ENSG00000171858.13 3.793 RPS5/ENSG00000083845.4 3.79 RPS15/ENSG00000115268.5 3.788 RPS10/ENSG00000124614.9 3.782 RPL36A/ENSG00000241343.5 3.761 RPL26/ENSG00000161970.8 3.746 ATP5B/ENSG00000110955.3 3.745 TPI1/ENSG00000111669.9 3.74 COX6C/ENSG00000164919.5 3.735 SNRPD2/ENSG00000125743.6 3.725 PRDX2/ENSG00000167815.7 3.717 ATP5L/ENSG00000167283.3 3.715 RPS16/ENSG00000105193.4 3.712 RPL18/ENSG00000063177.8 3.711 RPSA/ENSG00000168028.9 3.709 SON/ENSG00000159140.13 3.702 RPS12/ENSG00000112306.7 3.697 SRP9/ENSG00000143742.8 3.694 DYNLL1/ENSG00000088986.6 3.69 PTMA/ENSG00000187514.10 3.681 STMN1/ENSG00000117632.16 3.677 DDX5/ENSG00000108654.7 3.67 PSMB5/ENSG00000100804.14 3.666 UBA52/ENSG00000221983.3 3.646 GABARAP/ENSG00000170296.5 3.645 RPS7/ENSG00000171863.8 3.645 TMA7/ENSG00000232112.3 3.629 NACA/ENSG00000196531.6 3.626 PPP1CB/ENSG00000213639.5 3.617 H3F3A/ENSG00000163041.5 3.613 RPL6/ENSG00000089009.10 3.61 PSMB4/ENSG00000159377.6 3.608 HIST1H4C/ENSG00000197061.3 3.604 YWHAE/ENSG00000108953.12 3.598 ATP5G2/ENSG00000135390.13 3.597 MT-ND3/ENSG00000198840.2 3.59 COX7A2/ENSG00000112695.7 3.573 SLIRP/ENSG00000119705.5 3.55 EIF1/ENSG00000173812.6 3.534 ATP5I/ENSG00000169020.5 3.527 RPL37/ENSG00000145592.9 3.521 UBL5/ENSG00000198258.6 3.515 PSMB1/ENSG00000008018.8 3.5 OST4/ENSG00000228474.1 3.499 RPLP2/ENSG00000177600.4 3.495 ATP5A1/ENSG00000152234.11 3.486 PSMB6/ENSG00000142507.5 3.476 HSP90AA1/ENSG00000080824.14 3.457 TMSB10/ENSG00000034510.4 3.449 SSR4/ENSG00000180879.8 3.446 NGFRAP1/ENSG00000166681.9 3.443 HNRNPA2B1/ENSG00000122566.16 3.432 EEF1B2/ENSG00000114942.9 3.404 HNRNPH1/ENSG00000169045.13 3.357 TBCA/ENSG00000171530.9 3.34 H2AFZ/ENSG00000164032.7 3.339 RPL10A/ENSG00000198755.6 3.332 ATP5O/ENSG00000241837.2 3.321 TCEB2/ENSG00000103363.10 3.311 ATP5F1/ENSG00000116459.6 3.293 GSTP1/ENSG00000084207.11 3.285 HMGN2/ENSG00000198830.6 3.282 ATP5C1/ENSG00000165629.15 3.266 UBC/ENSG00000150991.10 3.245 HNRNPC/ENSG00000092199.13 3.218 PPIB/ENSG00000166794.4 3.126 USMG5/ENSG00000173915.8 3.12 MDH1/ENSG00000014641.13 3.111 YWHAZ/ENSG00000164924.13 3.104 OSTC/ENSG00000198856.8 3.104 NEDD8/ENSG00000129559.8 3.084 TXNDC17/ENSG00000129235.6 3.075 FAU/ENSG00000149806.6 3.059 HINT1/ENSG00000169567.7 3.033 HSP90B1/ENSG00000166598.8 3.006 ATP6V1G1/ENSG00000136888.6 2.981 CAPZA1/ENSG00000116489.8 2.98 C11ORF58/ENSG00000110696.5 2.936 CD63/ENSG00000135404.7 2.926 TMEM258/ENSG00000134825.8 2.924 NDUFB4/ENSG00000065518.7 2.919 HNRNPA1/ENSG00000135486.13 2.886 EIF3L/ENSG00000100129.12 2.876 HMGB1/ENSG00000189403.10 2.843 MORF4L2/ENSG00000123562.11 2.828 ATP6V0E1/ENSG00000113732.4 2.823 SNRPG/ENSG00000143977.9 2.783 GNAS/ENSG00000087460.18 2.782 SLC25A5/ENSG00000005022.5 2.771 MYL12A/ENSG00000101608.6 2.753 "SNRPN,SNURF/ENSG00000214265.6" 2.752 COX6B1/ENSG00000126267.4 2.751 "C7ORF76,SHFM1/ENSG00000127922.5" 2.742 ATP5J/ENSG00000154723.8 2.741 HSBP1/ENSG00000230989.2 2.727 NDUFA13/ENSG00000186010.12 2.726 EIF4A2/ENSG00000156976.10 2.726 PCBP2/ENSG00000197111.11 2.723 RPL13/ENSG00000167526.9 2.705 PSMA1/ENSG00000129084.13 2.69 SET/ENSG00000119335.12 2.682 EIF4G2/ENSG00000110321.11 2.661 DYNLT1/ENSG00000146425.6 2.658 SRSF6/ENSG00000124193.10 2.642 C6ORF62/ENSG00000112308.8 2.617 MTRNR2L12/ENSG00000269028.2 2.585 ROMO1/ENSG00000125995.11 2.583 RPS26/ENSG00000197728.5 2.555 NDUFC2/ENSG00000151366.8 2.545 AL590762.1/ENSG00000255591.1 2.538 RAB11A/ENSG00000103769.5 2.526 SEC61B/ENSG00000106803.5 2.525 NDUFB2/ENSG00000090266.8 2.521 CD24P4/ENSG00000185275.6 2.498 ATP5G3/ENSG00000154518.5 2.497 XRCC5/ENSG00000079246.11 2.496 ATPIF1/ENSG00000130770.13 2.494 ARPC2/ENSG00000163466.11 2.48 RPL28/ENSG00000108107.8 2.463 NOP10/ENSG00000182117.4 2.456 UQCR11/ENSG00000127540.7 2.448 NDUFB9/ENSG00000147684.3 2.411 MYL12B/ENSG00000118680.8 2.401 ANXA5/ENSG00000164111.10 2.395 PSMB3/ENSG00000108294.4 2.395 PET100/ENSG00000229833.4 2.391 SEPW1/ENSG00000178980.10 2.381 NDUFB8/ENSG00000166136.11 2.35 LUC7L3/ENSG00000108848.10 2.338 PRDX3/ENSG00000165672.5 2.324 BTF3/ENSG00000145741.11 2.32 EDF1/ENSG00000107223.8 2.316 RBM39/ENSG00000131051.15 2.306 COMMD6/ENSG00000188243.8 2.28 RAN/ENSG00000132341.6 2.268 TMSB4X/ENSG00000205542.6 2.267 NAP1L1/ENSG00000187109.9 2.264 BRK1/ENSG00000254999.2 2.246 STRAP/ENSG00000023734.6 2.245 NONO/ENSG00000147140.10 2.233 RPL36AL/ENSG00000165502.6 2.23 ARPC3/ENSG00000111229.11 2.224 HNRPDL/ENSG00000152795.13 2.216 GTF2A2/ENSG00000140307.6 2.207 DAD1/ENSG00000129562.6 2.206 SRSF3/ENSG00000112081.11 2.174 PSMA3/ENSG00000100567.8 2.16 PSMA7/ENSG00000101182.10 2.153 HMGN3/ENSG00000118418.10 2.145 CUTA/ENSG00000112514.10 2.135 SEC61G/ENSG00000132432.9 2.122 SUB1/ENSG00000113387.7 2.102 C14ORF2/ENSG00000156411.5 2.09 PARK7/ENSG00000116288.8 2.088 PSMA2/ENSG00000106588.6 2.063 ENO1/ENSG00000074800.9 2.052 RP5-857K21.11/ENSG00000198744.5 2.047 CFL1/ENSG00000172757.7 2.045 RPS4X/ENSG00000198034.6 2.033 NDUFA3/ENSG00000170906.11 2.032 UBE2V1/ENSG00000244687.7 2.026 CSNK1A1/ENSG00000113712.11 2.014 ENY2/ENSG00000120533.8 2.014 GNG5/ENSG00000174021.6 2.002 C8ORF59/ENSG00000176731.7 1.988 CLIC1/ENSG00000213719.4 1.986 LAMTOR5/ENSG00000134248.9 1.982 MATR3/ENSG00000015479.13 1.972 SF3B14/ENSG00000115128.6 1.962 CAPZA2/ENSG00000198898.7 1.948 CDC42/ENSG00000070831.11 1.946 POMP/ENSG00000132963.7 1.942 UQCRB/ENSG00000156467.5 1.931 ACP1/ENSG00000143727.11 1.93 UBE2L3/ENSG00000185651.10 1.915 EIF3E/ENSG00000104408.5 1.908 EMC4/ENSG00000128463.8 1.904 UQCRQ/ENSG00000164405.6 1.895 SF3B1/ENSG00000115524.10 1.894 SSR2/ENSG00000163479.9 1.887 UFC1/ENSG00000143222.7 1.885 PSMB7/ENSG00000136930.8 1.875 MGST3/ENSG00000143198.7 1.874 PPP2R5C/ENSG00000078304.14 1.858 SRSF11/ENSG00000116754.9 1.857 PSMA6/ENSG00000100902.6 1.855 KRTCAP2/ENSG00000163463.6 1.824 UBE2D3/ENSG00000109332.15 1.822 SRSF10/ENSG00000188529.10 1.81 SEPT7/ENSG00000122545.13 1.798 GDI2/ENSG00000057608.11 1.788 RP11-742N3.1/ENSG00000227097.4 1.786 PSMA4/ENSG00000041357.11 1.778 NDUFV2/ENSG00000178127.8 1.776 SAP18/ENSG00000150459.7 1.774 VPS29/ENSG00000111237.14 1.774 LDHB/ENSG00000111716.8 1.771 PSME1/ENSG00000092010.10 1.77 COPZ1/ENSG00000111481.5 1.76 C17ORF76-AS1/ENSG00000175061.12 1.76 NDUFA11/ENSG00000174886.8 1.758 RNF7/ENSG00000114125.9 1.758 UQCR10/ENSG00000184076.10 1.751 SLC25A3/ENSG00000075415.8 1.743 ZFAS1/ENSG00000177410.8 1.739 GAS5/ENSG00000234741.2 1.739 CCNI/ENSG00000118816.5 1.738 BEX1/ENSG00000133169.5 1.732 CCT3/ENSG00000163468.9 1.731 UQCRH/ENSG00000173660.7 1.731 DBI/ENSG00000155368.12 1.729 SEP15/ENSG00000183291.11 1.724 NDUFB3/ENSG00000119013.4 1.722 WDR83OS/ENSG00000105583.5 1.721 RPS4Y1/ENSG00000129824.9 1.709 SUMO2/ENSG00000188612.7 1.706 EIF6/ENSG00000242372.2 1.703 COX16/ENSG00000133983.10 1.702 DYNLRB1/ENSG00000125971.12 1.694 FTH1/ENSG00000167996.11 1.693 ANAPC16/ENSG00000166295.4 1.69 DSTN/ENSG00000125868.10 1.679 PPP1R12A/ENSG00000058272.11 1.673 ZFAND6/ENSG00000086666.14 1.66 SSBP1/ENSG00000106028.6 1.66 TMED10/ENSG00000170348.4 1.657 DPY30/ENSG00000162961.9 1.641 MNF1/ENSG00000137288.4 1.64 GTF3C6/ENSG00000155115.6 1.639 SARS/ENSG00000031698.8 1.633 SOD1/ENSG00000142168.10 1.63 COX8A/ENSG00000176340.3 1.63 VDAC3/ENSG00000078668.9 1.63 ATOX1/ENSG00000177556.7 1.629 HSPD1/ENSG00000144381.12 1.609 CDV3/ENSG00000091527.11 1.607 SEC31A/ENSG00000138674.12 1.606 CCNC/ENSG00000112237.8 1.606 PFDN1/ENSG00000113068.5 1.596 SNRPC/ENSG00000124562.5 1.594 NDUFA6/ENSG00000184983.5 1.586 EIF1B/ENSG00000114784.3 1.585 NDUFC1/ENSG00000109390.7 1.583 PSENEN/ENSG00000205155.3 1.579 COA3/ENSG00000183978.7 1.579 NDUFB5/ENSG00000136521.8 1.576 YBX1/ENSG00000065978.13 1.573 CTTN/ENSG00000085733.11 1.56 CCT6A/ENSG00000146731.6 1.557 TRA2A/ENSG00000164548.6 1.554 ATP6V1F/ENSG00000128524.4 1.551 TAX1BP1/ENSG00000106052.8 1.549 ARL6IP1/ENSG00000170540.10 1.548 ATP5H/ENSG00000167863.7 1.548 COPS6/ENSG00000168090.5 1.538 RHOA/ENSG00000067560.6 1.536 THOC2/ENSG00000125676.14 1.534 CSDE1/ENSG00000009307.11 1.527 ATP6V0B/ENSG00000117410.9 1.527 RBM8A/ENSG00000131795.7 1.521 PABPC1/ENSG00000070756.9 1.517 NHP2L1/ENSG00000100138.9 1.516 CALM1/ENSG00000198668.6 1.515 SPCS2/ENSG00000118363.7 1.513 UQCRC1/ENSG00000010256.6 1.507 PNISR/ENSG00000132424.10 1.501 COX5B/ENSG00000135940.2 1.499 CTC-425F1.4/ENSG00000267458.1 1.498 COX7A2L/ENSG00000115944.9 1.496 ARL3/ENSG00000138175.7 1.493 PSMD1/ENSG00000173692.8 1.488 SH3BGRL3/ENSG00000142669.9 1.483 CHP1/ENSG00000187446.7 1.48 ARF4/ENSG00000168374.6 1.472 SRP19/ENSG00000153037.7 1.464 SNW1/ENSG00000100603.9 1.458 BCLAF1/ENSG00000029363.11 1.451 SSR1/ENSG00000124783.8 1.45 PAPOLA/ENSG00000090060.13 1.449 ARPC4/ENSG00000241553.7 1.447 C19ORF53/ENSG00000104979.4 1.445 GPX4/ENSG00000167468.12 1.443 PSMC4/ENSG00000013275.3 1.441 SEC62/ENSG00000008952.12 1.431 PRRC2C/ENSG00000117523.11 1.428 TLK1/ENSG00000198586.9 1.425 RAB18/ENSG00000099246.12 1.421 ARPC1A/ENSG00000241685.4 1.413 TOB1/ENSG00000141232.4 1.411 MRPL27/ENSG00000108826.11 1.406 NDUFA1/ENSG00000125356.6 1.405 EIF3I/ENSG00000084623.7 1.405 JKAMP/ENSG00000050130.13 1.404 MRPL20/ENSG00000242485.1 1.401 ATF4/ENSG00000128272.10 1.4 HSPA5/ENSG00000044574.7 1.39 "RBM14-RBM4,RBM4/ENSG00000173933.15" 1.389 SPCS1/ENSG00000114902.9 1.385 EIF5/ENSG00000100664.6 1.38 ARF1/ENSG00000143761.9 1.379 HNRNPR/ENSG00000125944.13 1.375 RPS2/ENSG00000140988.11 1.373 C14ORF166/ENSG00000087302.4 1.372 SNX6/ENSG00000129515.14 1.371 CNBP/ENSG00000169714.12 1.365 SUMO1/ENSG00000116030.12 1.364 CCT8/ENSG00000156261.8 1.36 CHMP5/ENSG00000086065.9 1.358 TMEM33/ENSG00000109133.8 1.354 RBM3/ENSG00000102317.13 1.353 SMIM7/ENSG00000214046.4 1.347 HIGD2A/ENSG00000146066.2 1.341 PTP4A2/ENSG00000184007.13 1.339 TUBA1A/ENSG00000167552.9 1.335 SLTM/ENSG00000137776.12 1.334 EBP/ENSG00000147155.6 1.332 DDX17/ENSG00000100201.14 1.329 SEPT2/ENSG00000168385.13 1.324 OCIAD1/ENSG00000109180.10 1.32 MARCKS/ENSG00000155130.5 1.319 RTN4/ENSG00000115310.13 1.317 HDLBP/ENSG00000115677.12 1.309 TCEAL8/ENSG00000180964.12 1.309 TTTY15/ENSG00000233864.3 1.299 RPL22/ENSG00000116251.5 1.299 RARS/ENSG00000113643.4 1.295 COPS5/ENSG00000121022.9 1.294 MRPS21/ENSG00000187145.10 1.294 TBL1XR1/ENSG00000177565.11 1.282 ANAPC11/ENSG00000141552.13 1.28 HIGD1A/ENSG00000181061.9 1.275 CTNNB1/ENSG00000168036.12 1.274 RBX1/ENSG00000100387.8 1.273 PHPT1/ENSG00000054148.13 1.265 TOMM7/ENSG00000196683.6 1.263 TIMM8B/ENSG00000150779.7 1.263 TSPYL1/ENSG00000189241.6 1.259 SELT/ENSG00000198843.8 1.25 RPL7L1/ENSG00000146223.10 1.243 CCT2/ENSG00000166226.7 1.237 TSG101/ENSG00000074319.8 1.235 SRRM2/ENSG00000167978.12 1.234 PKM/ENSG00000067225.13 1.233 DNAJA1/ENSG00000086061.11 1.223 KTN1/ENSG00000126777.13 1.218 RDX/ENSG00000137710.10 1.215 CANX/ENSG00000127022.10 1.215 SRSF5/ENSG00000100650.11 1.213 MTCH2/ENSG00000109919.5 1.212 CHD4/ENSG00000111642.10 1.208 SAR1A/ENSG00000079332.9 1.197 CNOT7/ENSG00000198791.7 1.192 TXN2/ENSG00000100348.5 1.19 MRPL33/ENSG00000243147.3 1.187 DMKN/ENSG00000161249.16 1.185 SELK/ENSG00000113811.6 1.182 EIF2S3/ENSG00000130741.5 1.178 NDUFAB1/ENSG00000004779.5 1.176 MTIF3/ENSG00000122033.10 1.176 PSMC2/ENSG00000161057.6 1.17 PPP6R3/ENSG00000110075.10 1.166 CCT5/ENSG00000150753.7 1.162 LINC00493/ENSG00000232388.1 1.159 COX7B/ENSG00000131174.4 1.157 MCFD2/ENSG00000180398.7 1.147 FAM211A/ENSG00000181350.7 1.144 STT3A/ENSG00000134910.8 1.143 ZBTB8OS/ENSG00000176261.11 1.142 EID1/ENSG00000255302.3 1.131 NEMF/ENSG00000165525.13 1.122 MINOS1/ENSG00000173436.9 1.119 QARS/ENSG00000172053.10 1.115 TMEM14C/ENSG00000111843.9 1.11 PSMD8/ENSG00000099341.7 1.11 ZNF638/ENSG00000075292.13 1.11 CAP1/ENSG00000131236.12 1.109 UXT/ENSG00000126756.7 1.107 OAZ1/ENSG00000104904.7 1.103 VDAC2/ENSG00000165637.9 1.101 SH3D19/ENSG00000109686.12 1.099 VPS35/ENSG00000069329.11 1.089 PGK1/ENSG00000102144.9 1.077 MRFAP1/ENSG00000179010.10 1.073 DNAJC3/ENSG00000102580.10 1.073 PSMD7/ENSG00000103035.6 1.068 DDOST/ENSG00000244038.4 1.065 CTB-89H12.4/ENSG00000230551.3 1.063 LAMTOR1/ENSG00000149357.5 1.063 HNRNPH2/ENSG00000126945.8 1.063 ALDOA/ENSG00000149925.12 1.063 RAB1A/ENSG00000138069.12 1.062 DDX24/ENSG00000089737.11 1.056 EPCAM/ENSG00000119888.6 1.055 DDB1/ENSG00000167986.9 1.053 CHD2/ENSG00000173575.13 1.05 SNRPE/ENSG00000182004.8 1.048 GOSR1/ENSG00000108587.10 1.044 ACTR2/ENSG00000138071.9 1.04 MRPL32/ENSG00000106591.3 1.04 SRRM1/ENSG00000133226.12 1.038 RP11-138C9.1/ENSG00000264558.1 1.037 WBP5/ENSG00000185222.7 1.035 CCAR1/ENSG00000060339.9 1.032 RBM34/ENSG00000188739.10 1.03 TPM3/ENSG00000143549.14 1.029 RBM25/ENSG00000119707.9 1.029 SAP30BP/ENSG00000161526.10 1.027 LSM12/ENSG00000161654.5 1.027 NSRP1/ENSG00000126653.11 1.024 TOMM6/ENSG00000214736.3 1.02 BUD31/ENSG00000106245.5 1.017 EPRS/ENSG00000136628.12 1.016 COPB1/ENSG00000129083.8 1.015 TTC37/ENSG00000198677.6 1.007 DNAJC19/ENSG00000205981.2 1.007 ATG12/ENSG00000145782.8 1.007 LAMTOR2/ENSG00000116586.7 1.005 NKTR/ENSG00000114857.13 1.001 DNAJA2/ENSG00000069345.7 1 SARNP/ENSG00000205323.4 1 EIF4B/ENSG00000063046.13 0.991 TRAPPC2L/ENSG00000167515.6 0.991 SSR3/ENSG00000114850.2 0.99 EIF2A/ENSG00000144895.7 0.983 SLC35B1/ENSG00000121073.8 0.982 PRDX1/ENSG00000117450.9 0.982 CPNE1/ENSG00000214078.7 0.98 TCP1/ENSG00000120438.7 0.976 PSMD13/ENSG00000185627.13 0.976 EIF3H/ENSG00000147677.6 0.97 DERL2/ENSG00000072849.6 0.963 MTRNR2L9/ENSG00000255633.3 0.961 SRP54/ENSG00000100883.7 0.957 PCM1/ENSG00000078674.13 0.956 SCAF11/ENSG00000139218.12 0.956 TMBIM4/ENSG00000155957.12 0.946 RP11-703G6.1/ENSG00000249614.1 0.943 MTRNR2L2/ENSG00000271043.1 0.94 MTRNR2L8/ENSG00000255823.1 0.937 SCFD1/ENSG00000092108.16 0.935 EIF3M/ENSG00000149100.8 0.931 MAGED1/ENSG00000179222.12 0.93 UBE2K/ENSG00000078140.9 0.93 C4ORF3/ENSG00000164096.10 0.928 EAPP/ENSG00000129518.4 0.928 IK/ENSG00000113141.10 0.926 SSB/ENSG00000138385.11 0.925 ADAR/ENSG00000160710.11 0.921 SF3B2/ENSG00000087365.10 0.918 CNPY2/ENSG00000257727.1 0.915 WAC/ENSG00000095787.16 0.911 TCEAL4/ENSG00000133142.13 0.909 NDUFB7/ENSG00000099795.2 0.9 HECTD1/ENSG00000092148.8 0.899 BCAP31/ENSG00000185825.10 0.895 YWHAB/ENSG00000166913.8 0.888 CHMP2A/ENSG00000130724.4 0.885 NSA2/ENSG00000164346.5 0.883 NUTF2/ENSG00000102898.6 0.881 DYNC1H1/ENSG00000197102.6 0.88 KARS/ENSG00000065427.10 0.876 PCBP1/ENSG00000169564.5 0.875 IMMT/ENSG00000132305.16 0.875 ANAPC15/ENSG00000110200.4 0.874 LAMTOR4/ENSG00000188186.6 0.872 CSNK2B/ENSG00000204435.9 0.871 MNAT1/ENSG00000020426.6 0.87 SPINT2/ENSG00000167642.8 0.87 H2AFV/ENSG00000105968.14 0.866 TAF7/ENSG00000178913.5 0.86 SRSF9/ENSG00000111786.4 0.86 EWSR1/ENSG00000182944.13 0.858 ESD/ENSG00000139684.8 0.855 TMX2/ENSG00000213593.5 0.853 SEC22B/ENSG00000223380.3 0.852 SMC3/ENSG00000108055.9 0.852 TUBA1B/ENSG00000123416.11 0.851 PDZD11/ENSG00000120509.6 0.849 USP8/ENSG00000138592.9 0.849 CALR/ENSG00000179218.8 0.835 UBXN4/ENSG00000144224.12 0.83 FAM213A/ENSG00000122378.9 0.829 EZR/ENSG00000092820.13 0.828 ZRANB2/ENSG00000132485.8 0.828 COMMD9/ENSG00000110442.7 0.827 NOP56/ENSG00000101361.10 0.825 COX20/ENSG00000203667.5 0.825 SEC13/ENSG00000157020.13 0.819 SNHG14/ENSG00000224078.6 0.818 POLR1C/ENSG00000171453.13 0.81 HNRNPL/ENSG00000104824.11 0.809 PRPF8/ENSG00000174231.12 0.806 POLR2J/ENSG00000005075.11 0.802 ACTR3/ENSG00000115091.7 0.798 RPS27L/ENSG00000185088.8 0.796 RAB13/ENSG00000143545.4 0.796 PHF14/ENSG00000106443.10 0.793 NDUFA9/ENSG00000139180.5 0.788 NRD1/ENSG00000078618.15 0.784 TXNDC9/ENSG00000115514.7 0.781 NFU1/ENSG00000169599.8 0.778 MYEOV2/ENSG00000172428.5 0.773 PPHLN1/ENSG00000134283.12 0.772 SNHG5/ENSG00000203875.5 0.772 SUGT1/ENSG00000165416.9 0.767 YIPF5/ENSG00000145817.11 0.766 QRICH1/ENSG00000198218.6 0.762 ADAM10/ENSG00000137845.10 0.756 SEPT11/ENSG00000138758.7 0.756 SMIM14/ENSG00000163683.6 0.753 ZFR/ENSG00000056097.11 0.752 G3BP2/ENSG00000138757.10 0.752 CHCHD5/ENSG00000125611.11 0.746 BIRC6/ENSG00000115760.9 0.746 TUG1/ENSG00000253352.4 0.745 TXNL1/ENSG00000091164.8 0.742 SHOC2/ENSG00000108061.7 0.738 BRD2/ENSG00000204256.7 0.733 C9ORF78/ENSG00000136819.10 0.732 RSL1D1/ENSG00000171490.8 0.73 SCNM1/ENSG00000163156.7 0.729 DNAJC7/ENSG00000168259.9 0.723 DPCD/ENSG00000166171.8 0.722 ATAD1/ENSG00000138138.9 0.721 MAGED2/ENSG00000102316.11 0.721 FAM96A/ENSG00000166797.6 0.72 EIF4E/ENSG00000151247.8 0.719 HUWE1/ENSG00000086758.11 0.716 MED4/ENSG00000136146.10 0.715 IGBP1/ENSG00000089289.11 0.715 ACAA2/ENSG00000167315.13 0.71 UNC50/ENSG00000115446.7 0.709 DIABLO/ENSG00000184047.11 0.708 HP1BP3/ENSG00000127483.13 0.703 SNRNP200/ENSG00000144028.10 0.702 SDHAF2/ENSG00000167985.2 0.701 PDIA3/ENSG00000167004.8 0.701 FNTA/ENSG00000168522.8 0.7 ARMC8/ENSG00000114098.13 0.699 SND1/ENSG00000197157.6 0.698 DNAJC16/ENSG00000116138.8 0.698 MRPS11/ENSG00000181991.11 0.697 NDUFA2/ENSG00000131495.4 0.695 FAM103A1/ENSG00000169612.3 0.694 DYNC1LI2/ENSG00000135720.8 0.693 UBR4/ENSG00000127481.10 0.692 CLK1/ENSG00000013441.11 0.69 UFSP2/ENSG00000109775.6 0.688 UGP2/ENSG00000169764.10 0.688 ERGIC2/ENSG00000087502.13 0.685 WSB1/ENSG00000109046.10 0.685 NDUFA10/ENSG00000130414.7 0.679 LYPLAL1/ENSG00000143353.7 0.679 ENSA/ENSG00000143420.13 0.675 PJA2/ENSG00000198961.5 0.674 RNF181/ENSG00000168894.5 0.674 UPF3A/ENSG00000169062.10 0.674 TRAM1/ENSG00000067167.3 0.672 DNAJC8/ENSG00000126698.6 0.671 DCTN2/ENSG00000175203.11 0.669 MPHOSPH10/ENSG00000124383.3 0.668 UBE2B/ENSG00000119048.3 0.664 FAM219B/ENSG00000178761.10 0.663 CDC42SE2/ENSG00000158985.9 0.663 DYNC1I2/ENSG00000077380.11 0.661 DNAJC10/ENSG00000077232.11 0.661 ANKRD17/ENSG00000132466.13 0.659 TUFM/ENSG00000178952.4 0.658 SEC63/ENSG00000025796.9 0.655 RSF1/ENSG00000048649.9 0.655 PSMD6/ENSG00000163636.6 0.655 RNF216P1/ENSG00000196204.7 0.654 PLEKHA5/ENSG00000052126.10 0.651 ZSWIM7/ENSG00000214941.3 0.651 ZCRB1/ENSG00000139168.3 0.648 DPH3/ENSG00000154813.5 0.645 TMEM50A/ENSG00000183726.6 0.644 ZFAND5/ENSG00000107372.8 0.644 SYF2/ENSG00000117614.5 0.639 ZMYM6NB/ENSG00000243749.1 0.633 CCDC167/ENSG00000198937.8 0.63 YIPF6/ENSG00000181704.7 0.629 BLOC1S1/ENSG00000135441.3 0.627 BFAR/ENSG00000103429.6 0.618 LAPTM4A/ENSG00000068697.6 0.615 RN7SL1/ENSG00000258486.1 0.615 SETD5/ENSG00000168137.11 0.615 DST/ENSG00000151914.13 0.613 ATP5E/ENSG00000124172.5 0.613 MIER1/ENSG00000198160.10 0.611 TFG/ENSG00000114354.8 0.607 NUPL2/ENSG00000136243.12 0.607 ASNSD1/ENSG00000138381.4 0.606 USP14/ENSG00000101557.9 0.603 ZC3H15/ENSG00000065548.13 0.603 TDG/ENSG00000139372.10 0.602 FAM104B/ENSG00000182518.9 0.602 CDK2AP1/ENSG00000111328.2 0.601 LSM14A/ENSG00000257103.3 0.601 TCEA1/ENSG00000187735.8 0.6 TMCO1/ENSG00000143183.12 0.6 CHMP4A/ENSG00000254505.3 0.597 OGT/ENSG00000147162.9 0.596 NDUFA4/ENSG00000189043.5 0.596 BANF1/ENSG00000175334.3 0.593 DDX6/ENSG00000110367.6 0.593 UBE2A/ENSG00000077721.11 0.591 C9ORF123/ENSG00000137038.7 0.589 ITGB1BP1/ENSG00000119185.8 0.588 AGPAT1/ENSG00000204310.6 0.588 DRAM2/ENSG00000156171.10 0.588 EIF2AK1/ENSG00000086232.8 0.587 ETF1/ENSG00000120705.8 0.585 TSTD1/ENSG00000215845.6 0.583 RP11-286N22.8/ENSG00000256591.1 0.583 MAD2L1BP/ENSG00000124688.9 0.579 IDH3B/ENSG00000101365.16 0.576 AP2M1/ENSG00000161203.9 0.576 COMMD2/ENSG00000114744.4 0.573 SREK1IP1/ENSG00000153006.9 0.572 PPP2R2A/ENSG00000221914.4 0.571 FUS/ENSG00000089280.14 0.567 NCOR1/ENSG00000141027.16 0.566 PPP1R10/ENSG00000204569.5 0.566 CCDC25/ENSG00000147419.12 0.564 AHCYL1/ENSG00000168710.13 0.564 CETN2/ENSG00000147400.8 0.562 ARL14EP/ENSG00000152219.4 0.562 SREK1/ENSG00000153914.11 0.562 SUGP2/ENSG00000064607.12 0.562 LARP4/ENSG00000161813.16 0.561 FNBP1L/ENSG00000137942.12 0.561 PSME4/ENSG00000068878.10 0.557 SLC25A36/ENSG00000114120.7 0.555 IVD/ENSG00000128928.4 0.555 ZC3H11A/ENSG00000058673.11 0.554 CTNNA1/ENSG00000044115.15 0.553 PRRC1/ENSG00000164244.16 0.551 UBXN1/ENSG00000162191.9 0.549 MRPS18B/ENSG00000204568.7 0.547 STT3B/ENSG00000163527.5 0.545 PSMC6/ENSG00000100519.6 0.545 ERP29/ENSG00000089248.6 0.542 NAGK/ENSG00000124357.7 0.541 MIF/ENSG00000240972.1 0.54 PEX2/ENSG00000164751.10 0.54 EIF3K/ENSG00000178982.5 0.539 TCTN3/ENSG00000119977.15 0.539 LSM1/ENSG00000175324.5 0.539 SFPQ/ENSG00000116560.6 0.539 KRT8/ENSG00000170421.7 0.537 PSMD11/ENSG00000108671.5 0.536 PDCD6IP/ENSG00000170248.9 0.534 CGGBP1/ENSG00000163320.6 0.534 APPL1/ENSG00000157500.6 0.533 AAMDC/ENSG00000087884.10 0.529 TRNT1/ENSG00000072756.12 0.528 CLTC/ENSG00000141367.6 0.528 CLINT1/ENSG00000113282.9 0.526 SPTBN1/ENSG00000115306.11 0.524 WIPI2/ENSG00000157954.10 0.517 ATP6V1H/ENSG00000047249.12 0.516 NARF/ENSG00000141562.12 0.516 STAM/ENSG00000136738.10 0.515 LAMTOR3/ENSG00000109270.8 0.514 GDE1/ENSG00000006007.7 0.512 ECI2/ENSG00000198721.8 0.511 CPNE3/ENSG00000085719.7 0.511 IFT43/ENSG00000119650.8 0.508 DHX36/ENSG00000174953.9 0.507 GRSF1/ENSG00000132463.9 0.505 NCKAP1/ENSG00000061676.9 0.504 NUCB2/ENSG00000070081.10 0.504 CHMP2B/ENSG00000083937.4 0.502 NME7/ENSG00000143156.9 0.501 SNRPD3/ENSG00000100028.7 0.5 TIMM10B/ENSG00000132286.7 0.5 GGNBP2/ENSG00000005955.8 0.499 BLOC1S6/ENSG00000104164.6 0.498 YPEL5/ENSG00000119801.8 0.497 TMEM66/ENSG00000133872.9 0.496 SIPA1L1/ENSG00000197555.5 0.494 RP11-78A19.3/ENSG00000267165.1 0.494 POLR2L/ENSG00000177700.5 0.493 RP11-622K12.1/ENSG00000204272.6 0.491 SYNJ2BP/ENSG00000213463.3 0.491 HCG18/ENSG00000231074.4 0.491 ARHGAP1/ENSG00000175220.7 0.49 TMEM208/ENSG00000168701.14 0.489 SPCS3/ENSG00000129128.8 0.487 CBY1/ENSG00000100211.6 0.486 KDELR1/ENSG00000105438.4 0.483 TOMM20/ENSG00000173726.6 0.483 MLEC/ENSG00000110917.3 0.482 RAD17/ENSG00000152942.14 0.481 TTC17/ENSG00000052841.10 0.48 NEDD4/ENSG00000069869.11 0.48 KIF5B/ENSG00000170759.10 0.48 PSMD5/ENSG00000095261.9 0.479 VPS36/ENSG00000136100.8 0.478 CCDC59/ENSG00000133773.7 0.476 OSBPL9/ENSG00000117859.14 0.475 PCYOX1/ENSG00000116005.7 0.474 FUBP1/ENSG00000162613.12 0.474 MEAF6/ENSG00000163875.11 0.473 LRRFIP1/ENSG00000124831.14 0.473 EXOSC1/ENSG00000171311.8 0.473 LDOC1/ENSG00000182195.6 0.472 RMDN1/ENSG00000176623.7 0.471 NUCKS1/ENSG00000069275.12 0.47 MED21/ENSG00000152944.4 0.47 ILK/ENSG00000166333.9 0.469 ANAPC5/ENSG00000089053.8 0.469 HIBCH/ENSG00000198130.10 0.469 VIMP/ENSG00000131871.10 0.467 RAB10/ENSG00000084733.6 0.466 MRPS5/ENSG00000144029.7 0.463 FAF2/ENSG00000113194.8 0.462 RBFOX2/ENSG00000100320.18 0.458 NDUFS6/ENSG00000145494.7 0.457 GON4L/ENSG00000116580.13 0.457 GOLGA4/ENSG00000144674.12 0.456 RCN1/ENSG00000049449.4 0.454 C7ORF55/ENSG00000164898.8 0.454 HDHD2/ENSG00000167220.7 0.453 NDUFA7/ENSG00000267855.1 0.453 RP11-259O2.3/ENSG00000249731.1 0.452 NSDHL/ENSG00000147383.6 0.452 AC009120.6/ENSG00000259972.1 0.451 THUMPD3/ENSG00000134077.11 0.447 MPZL1/ENSG00000197965.7 0.447 AP2B1/ENSG00000006125.12 0.445 SPAG16/ENSG00000144451.14 0.444 FUNDC1/ENSG00000069509.5 0.443 ALDH7A1/ENSG00000164904.11 0.442 PPIG/ENSG00000138398.11 0.442 SLC39A11/ENSG00000133195.7 0.441 RP3-430N8.10/ENSG00000269972.1 0.441 LIMA1/ENSG00000050405.9 0.441 DSG2/ENSG00000046604.8 0.44 UBE2W/ENSG00000104343.15 0.439 ATPBD4/ENSG00000134146.7 0.439 NREP/ENSG00000134986.9 0.438 AP5M1/ENSG00000053770.7 0.438 VPS8/ENSG00000156931.10 0.437 MDP1/ENSG00000213920.4 0.437 GUCD1/ENSG00000138867.12 0.437 KIAA1429/ENSG00000164944.7 0.435 C8ORF76/ENSG00000189376.7 0.433 COG2/ENSG00000135775.8 0.433 FNBP4/ENSG00000109920.8 0.432 CSTF3/ENSG00000176102.7 0.432 CCDC82/ENSG00000149231.7 0.431 C11ORF31/ENSG00000211450.5 0.43 GPBP1L1/ENSG00000159592.6 0.429 HDAC8/ENSG00000147099.15 0.428 LRBA/ENSG00000198589.6 0.427 UBE3A/ENSG00000114062.13 0.426 KPNB1/ENSG00000108424.5 0.425 ELOF1/ENSG00000130165.6 0.425 MAP4/ENSG00000047849.17 0.424 GFM2/ENSG00000164347.13 0.423 PPCS/ENSG00000127125.7 0.422 IQGAP1/ENSG00000140575.8 0.422 TFRC/ENSG00000072274.8 0.421 UQCC/ENSG00000101019.17 0.421 ARL8B/ENSG00000134108.8 0.421 MRPS18C/ENSG00000163319.6 0.419 ATG5/ENSG00000057663.8 0.418 UTP23/ENSG00000147679.7 0.418 PCNP/ENSG00000081154.7 0.417 TEFM/ENSG00000172171.6 0.415 ZC3H13/ENSG00000123200.12 0.415 SERP1/ENSG00000120742.6 0.415 DDX1/ENSG00000079785.10 0.414 MRPL49/ENSG00000149792.4 0.413 FBXO11/ENSG00000138081.15 0.411 RPL3P4/ENSG00000232573.1 0.409 CUL3/ENSG00000036257.8 0.409 ACADM/ENSG00000117054.9 0.405 CTR9/ENSG00000198730.3 0.404 VPS4B/ENSG00000119541.5 0.404 CCNH/ENSG00000134480.9 0.403 RFWD2/ENSG00000143207.15 0.403 DENR/ENSG00000139726.6 0.402 SRRT/ENSG00000087087.14 0.4 VAPA/ENSG00000101558.9 0.398 PRDX5/ENSG00000126432.9 0.397 C1ORF131/ENSG00000143633.8 0.394 CKAP5/ENSG00000175216.10 0.394 TMEM41B/ENSG00000166471.6 0.393 TOR1AIP2/ENSG00000169905.7 0.392 SUCLG1/ENSG00000163541.7 0.392 TDP2/ENSG00000111802.9 0.392 ARPP19/ENSG00000128989.6 0.391 RAB21/ENSG00000080371.4 0.39 LMAN1/ENSG00000074695.5 0.39 SLMO2/ENSG00000101166.11 0.389 HSD17B11/ENSG00000198189.6 0.387 NIT1/ENSG00000158793.9 0.387 EIF3D/ENSG00000100353.13 0.385 C1GALT1C1/ENSG00000171155.7 0.384 SKA2/ENSG00000182628.8 0.384 ZC3HAV1/ENSG00000105939.8 0.382 DCUN1D1/ENSG00000043093.9 0.381 DDX42/ENSG00000198231.7 0.381 TIAL1/ENSG00000151923.13 0.38 TRAPPC13/ENSG00000113597.13 0.379 AKAP13/ENSG00000170776.15 0.377 DALRD3/ENSG00000178149.12 0.375 PFDN4/ENSG00000101132.5 0.374 B9D1/ENSG00000108641.10 0.373 UIMC1/ENSG00000087206.12 0.373 EIF2AK2/ENSG00000055332.11 0.373 RP11-96D1.11/ENSG00000262160.1 0.373 USP16/ENSG00000156256.10 0.372 PHF3/ENSG00000118482.7 0.372 BLMH/ENSG00000108578.10 0.371 AP3S1/ENSG00000177879.10 0.371 CTD-2545M3.2/ENSG00000268854.1 0.369 TMEM106B/ENSG00000106460.13 0.368 C1ORF56/ENSG00000143443.9 0.368 KRCC1/ENSG00000172086.7 0.367 SH3GLB1/ENSG00000097033.10 0.366 GFPT1/ENSG00000198380.7 0.365 USP34/ENSG00000115464.10 0.363 NKIRAS2/ENSG00000168256.13 0.363 ERGIC3/ENSG00000125991.14 0.362 RAB3GAP1/ENSG00000115839.13 0.361 TMEM170A/ENSG00000166822.8 0.359 USP7/ENSG00000187555.10 0.358 C20ORF111/ENSG00000132823.6 0.357 SPINT1/ENSG00000166145.10 0.357 ZNF143/ENSG00000166478.5 0.357 SUN1/ENSG00000164828.13 0.356 NUP98/ENSG00000110713.11 0.356 COX17/ENSG00000138495.2 0.356 FRYL/ENSG00000075539.9 0.354 AC007192.6/ENSG00000269145.1 0.354 FAM229B/ENSG00000203778.3 0.354 MED11/ENSG00000161920.5 0.353 XRCC6/ENSG00000196419.8 0.351 RNF187/ENSG00000168159.8 0.351 HDGF/ENSG00000143321.14 0.351 AC040977.1/ENSG00000269871.1 0.349 S100A13/ENSG00000189171.8 0.349 HACL1/ENSG00000131373.10 0.347 SLMAP/ENSG00000163681.10 0.347 PLS3/ENSG00000102024.11 0.347 DCAF6/ENSG00000143164.11 0.347 MCTS1/ENSG00000232119.2 0.347 ZNF585A/ENSG00000196967.6 0.346 PPP1CC/ENSG00000186298.7 0.346 PFN2/ENSG00000070087.9 0.344 ISY1/ENSG00000240682.5 0.343 ERH/ENSG00000100632.6 0.343 MRPS18A/ENSG00000096080.7 0.342 NAPG/ENSG00000134265.7 0.341 C12ORF65/ENSG00000130921.3 0.34 HSPA9/ENSG00000113013.8 0.339 ARIH1/ENSG00000166233.8 0.339 RBPJ/ENSG00000168214.16 0.338 TTC28-AS1/ENSG00000235954.2 0.337 BRCC3/ENSG00000185515.10 0.337 WSB2/ENSG00000176871.4 0.337 RAB8A/ENSG00000167461.7 0.337 CHD9/ENSG00000177200.11 0.337 RAB6A/ENSG00000175582.14 0.337 SMIM20/ENSG00000250317.4 0.337 AP2S1/ENSG00000042753.7 0.337 EIF2B4/ENSG00000115211.11 0.336 NSMCE2/ENSG00000156831.3 0.336 SUPT5H/ENSG00000196235.9 0.335 ECD/ENSG00000122882.5 0.335 CCNL1/ENSG00000163660.7 0.335 BLCAP/ENSG00000166619.7 0.334 BTF3L4/ENSG00000134717.13 0.334 PRR14L/ENSG00000183530.9 0.334 APEH/ENSG00000164062.8 0.333 GALNT1/ENSG00000141429.9 0.332 DAPK1/ENSG00000196730.8 0.331 LARP1/ENSG00000155506.12 0.331 TMEM165/ENSG00000134851.7 0.331 MAP3K4/ENSG00000085511.15 0.327 PPP6C/ENSG00000119414.7 0.326 ANAPC7/ENSG00000196510.8 0.326 RAC1/ENSG00000136238.13 0.325 TMEM199/ENSG00000244045.5 0.325 SENP6/ENSG00000112701.13 0.324 ZFC3H1/ENSG00000133858.11 0.324 BIRC2/ENSG00000110330.4 0.324 MOV10/ENSG00000155363.14 0.323 YTHDC1/ENSG00000083896.8 0.322 ANP32A/ENSG00000140350.11 0.322 ZNF451/ENSG00000112200.12 0.32 WBP11/ENSG00000084463.2 0.319 VPS25/ENSG00000131475.2 0.319 EXOC4/ENSG00000131558.10 0.318 DNAJC21/ENSG00000168724.10 0.317 ZNF271/ENSG00000257267.1 0.317 RP11-571M6.7/ENSG00000257342.1 0.316 SUMF2/ENSG00000129103.13 0.316 ZNF277/ENSG00000198839.5 0.315 RAD50/ENSG00000113522.9 0.314 TRPT1/ENSG00000149743.9 0.312 KDM5A/ENSG00000073614.7 0.311 TYW1/ENSG00000198874.8 0.31 CRCP/ENSG00000241258.2 0.31 AMZ2/ENSG00000196704.7 0.309 MTPN/ENSG00000105887.10 0.309 MTERFD2/ENSG00000122085.11 0.309 SECISBP2/ENSG00000187742.10 0.309 EIF4G3/ENSG00000075151.15 0.308 FAIM/ENSG00000158234.8 0.307 RP3-430N8.11/ENSG00000269987.1 0.307 MTDH/ENSG00000147649.5 0.307 TMEM9/ENSG00000116857.11 0.307 NFE2L2/ENSG00000116044.11 0.306 ATP5S/ENSG00000125375.10 0.304 CBWD2/ENSG00000136682.10 0.303 TLN1/ENSG00000137076.14 0.303 DHDDS/ENSG00000117682.12 0.302 CDKN2AIPNL/ENSG00000237190.3 0.301 BSDC1/ENSG00000160058.14 0.301 "HYPK,SERF2/ENSG00000242028.1" 0.3 JAGN1/ENSG00000171135.10 0.3 FOXRED1/ENSG00000110074.6 0.299 RP11-658F2.8/ENSG00000258297.1 0.299 MAT2A/ENSG00000168906.8 0.299 CASK/ENSG00000147044.15 0.298 TARBP2/ENSG00000139546.6 0.298 GTF2F1/ENSG00000125651.9 0.297 EIF3A/ENSG00000107581.7 0.297 HSD17B7/ENSG00000132196.8 0.297 AAGAB/ENSG00000103591.8 0.295 RSPRY1/ENSG00000159579.9 0.294 S100A11/ENSG00000163191.5 0.294 PDCD5/ENSG00000105185.6 0.293 MRPL47/ENSG00000136522.9 0.293 APLP2/ENSG00000084234.12 0.293 URI1/ENSG00000105176.13 0.292 MLF2/ENSG00000089693.6 0.292 SMCHD1/ENSG00000101596.9 0.29 CCNK/ENSG00000090061.13 0.289 CCDC43/ENSG00000180329.9 0.287 TNPO1/ENSG00000083312.13 0.287 ZNF7/ENSG00000147789.11 0.287 WDR11/ENSG00000120008.11 0.285 KIAA0196/ENSG00000164961.11 0.285 MYO10/ENSG00000145555.10 0.285 HPS1/ENSG00000107521.14 0.284 DECR1/ENSG00000104325.2 0.283 AC016683.6/ENSG00000189223.8 0.283 BCAP29/ENSG00000075790.6 0.283 RABGAP1/ENSG00000011454.12 0.282 TAF11/ENSG00000064995.12 0.281 ILF2/ENSG00000143621.12 0.281 RBM19/ENSG00000122965.6 0.281 C5ORF51/ENSG00000205765.4 0.281 SPOP/ENSG00000121067.13 0.281 ARHGAP12/ENSG00000165322.13 0.28 USP9X/ENSG00000124486.7 0.279 ODC1/ENSG00000115758.8 0.278 TAF10/ENSG00000166337.5 0.278 SUPT7L/ENSG00000119760.11 0.277 FAM206A/ENSG00000119328.7 0.276 CHD1L/ENSG00000131778.13 0.276 CCDC91/ENSG00000123106.6 0.276 SNX27/ENSG00000143376.8 0.276 LMBRD1/ENSG00000168216.6 0.276 MTA3/ENSG00000057935.9 0.274 MRPS14/ENSG00000120333.4 0.274 MIA3/ENSG00000154305.12 0.274 DNAL1/ENSG00000119661.9 0.274 FH/ENSG00000091483.6 0.273 PLGRKT/ENSG00000107020.5 0.273 ASH1L/ENSG00000116539.6 0.272 MED7/ENSG00000155868.7 0.271 PUS3/ENSG00000110060.4 0.271 APIP/ENSG00000149089.8 0.271 PLSCR3/ENSG00000187838.12 0.271 RBP1/ENSG00000114115.5 0.271 PIGC/ENSG00000135845.4 0.27 RALB/ENSG00000144118.9 0.27 DCTN3/ENSG00000137100.11 0.27 ARFGAP3/ENSG00000242247.6 0.27 XIAP/ENSG00000101966.8 0.269 SENP2/ENSG00000163904.8 0.267 CXORF40B/ENSG00000197021.4 0.266 IFNAR1/ENSG00000142166.8 0.266 SLC37A4/ENSG00000137700.11 0.266 EIF4G1/ENSG00000114867.14 0.265 CIR1/ENSG00000138433.11 0.265 NDUFB6/ENSG00000165264.6 0.264 USO1/ENSG00000138768.10 0.263 ATMIN/ENSG00000166454.5 0.263 USP22/ENSG00000124422.7 0.263 ITM2B/ENSG00000136156.7 0.262 DMXL1/ENSG00000172869.10 0.261 JPX/ENSG00000225470.2 0.26 NAA35/ENSG00000135040.11 0.259 RP11-572P18.1/ENSG00000220842.5 0.259 EIF4E2/ENSG00000135930.9 0.258 FAM135A/ENSG00000082269.12 0.258 COA6/ENSG00000168275.10 0.258 PPP4R1/ENSG00000154845.11 0.257 NUMB/ENSG00000133961.15 0.257 UBE3B/ENSG00000151148.9 0.255 YY1/ENSG00000100811.5 0.255 TOM1L1/ENSG00000141198.9 0.255 SECISBP2L/ENSG00000138593.4 0.255 EHBP1/ENSG00000115504.10 0.255 SERPINB1/ENSG00000021355.8 0.254 HEBP2/ENSG00000051620.5 0.253 FXR1/ENSG00000114416.12 0.252 GSK3B/ENSG00000082701.10 0.252 CWC15/ENSG00000150316.7 0.252 BAG5/ENSG00000166170.9 0.252 TRAPPC2/ENSG00000196459.9 0.251 RAP1GDS1/ENSG00000138698.9 0.251 CUL4B/ENSG00000158290.12 0.251 PDRG1/ENSG00000088356.4 0.25 ITCH/ENSG00000078747.8 0.25 NRAS/ENSG00000213281.4 Overrepresented GO terms in EP #1: Term Pvalue SRP-dependent cotranslational protein targeting to membrane 1.53E-85 translational initiation 4.17E-84 "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay " 1.24E-70 peptide biosynthetic process 1.29E-61 viral transcription 2.03E-55 mRNA catabolic process 5.19E-55 interspecies interaction between organisms 6.73E-53 cellular macromolecule catabolic process 6.75E-48 establishment of protein localization to membrane 5.04E-45 organonitrogen compound metabolic process 2.21E-43 ribonucleoprotein complex biogenesis 4.09E-43 establishment of protein localization to organelle 6.58E-43 intracellular protein transport 1.22E-39 rRNA processing 2.17E-38 nucleobase-containing compound catabolic process 1.97E-37 cellular macromolecule localization 7.65E-36 RNA processing 4.01E-32 posttranscriptional regulation of gene expression 3.29E-31 ncRNA metabolic process 4.67E-31 single-organism intracellular transport 1.70E-30 cellular macromolecular complex assembly 3.63E-30 organic substance catabolic process 1.59E-29 cellular amide metabolic process 1.69E-28 ATP synthesis coupled electron transport 1.41E-27 single-organism membrane organization 1.48E-27 ribonucleoprotein complex subunit organization 2.23E-26 electron transport chain 3.73E-23 ATP metabolic process 1.76E-20 cellular macromolecule biosynthetic process 8.04E-20 modification-dependent protein catabolic process 9.32E-20 purine nucleoside monophosphate metabolic process 1.55E-19 ribonucleoside monophosphate metabolic process 1.61E-19 ribonucleoside triphosphate metabolic process 3.83E-19 cellular respiration 7.32E-19 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition 1.65E-18 purine nucleoside triphosphate metabolic process 1.81E-18 organic substance transport 2.00E-17 negative regulation of ubiquitin-protein transferase activity 2.06E-17 "RNA splicing, via transesterification reactions " 2.46E-17 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 4.76E-17 anaphase-promoting complex-dependent catabolic process 5.20E-17 regulation of ubiquitin protein ligase activity 5.30E-17 positive regulation of ubiquitin-protein transferase activity 1.62E-16 "mitochondrial electron transport, NADH to ubiquinone " 1.97E-16 purine nucleoside metabolic process 2.75E-16 regulation of cellular amide metabolic process 3.47E-16 negative regulation of protein modification by small protein conjugation or removal 5.23E-16 ribonucleoside metabolic process 9.41E-16 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 2.05E-15 single-organism localization 2.72E-15 cytoplasmic translation 5.10E-15 regulation of cellular amino acid metabolic process 5.10E-15 protein complex subunit organization 1.40E-14 nucleic acid metabolic process 2.03E-14 regulation of cellular protein catabolic process 2.94E-14 cellular nitrogen compound biosynthetic process 2.96E-14 regulation of mRNA stability 5.06E-14 mitochondrial ATP synthesis coupled proton transport 5.11E-14 cellular component assembly 6.59E-14 mRNA metabolic process 6.86E-14 glycosyl compound metabolic process 8.28E-14 positive regulation of proteolysis involved in cellular protein catabolic process 8.99E-14 "Wnt signaling pathway, planar cell polarity pathway " 9.77E-14 nucleobase-containing compound metabolic process 1.36E-13 NIK/NF-kappaB signaling 3.56E-13 mitochondrial respiratory chain complex I assembly 5.69E-13 positive regulation of protein catabolic process 9.02E-13 protein complex biogenesis 9.52E-13 hydrogen transport 1.87E-12 establishment of planar polarity 2.03E-12 antigen processing and presentation of peptide antigen via MHC class I 2.36E-12 positive regulation of cellular catabolic process 3.56E-12 purine nucleotide metabolic process 4.63E-12 organic substance biosynthetic process 5.03E-12 ribonucleotide metabolic process 5.17E-12 "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent " 1.53E-11 stimulatory C-type lectin receptor signaling pathway 1.67E-11 regulation of catabolic process 2.56E-11 positive regulation of canonical Wnt signaling pathway 3.17E-11 cellular protein metabolic process 3.49E-11 Fc-epsilon receptor signaling pathway 3.52E-11 positive regulation of protein modification by small protein conjugation or removal 6.58E-11 antigen processing and presentation of exogenous peptide antigen 1.15E-10 "energy coupled proton transport, down electrochemical gradient " 1.31E-10 protein polyubiquitination 2.96E-10 nucleoside phosphate metabolic process 3.46E-10 cellular protein complex assembly 3.87E-10 formation of translation preinitiation complex 5.32E-10 mitochondrion organization 1.20E-09 tumor necrosis factor-mediated signaling pathway 1.75E-09 antigen processing and presentation 1.97E-09 regulation of morphogenesis of an epithelium 2.25E-09 nucleobase-containing compound biosynthetic process 2.26E-09 viral process 4.61E-09 protein modification by small protein conjugation 5.84E-09 immune response-activating cell surface receptor signaling pathway 2.11E-08 cellular amine metabolic process 4.17E-08 mitotic cell cycle process 6.96E-08 ribosomal small subunit assembly 8.23E-08 negative regulation of canonical Wnt signaling pathway 1.42E-07 intracellular transport 1.43E-07 ATP biosynthetic process 1.58E-07 hydrogen ion transmembrane transport 2.58E-07 "mitochondrial electron transport, cytochrome c to oxygen " 3.34E-07 regulation of translational initiation 4.76E-07 cell cycle 5.10E-07 "mRNA splicing, via spliceosome " 5.26E-07 regulation of organ morphogenesis 5.55E-07 ER to Golgi vesicle-mediated transport 6.01E-07 T cell receptor signaling pathway 6.49E-07 cellular component organization 7.93E-07 innate immune response-activating signal transduction 8.08E-07 regulation of cell cycle phase transition 8.69E-07 purine nucleoside triphosphate biosynthetic process 1.46E-06 membrane budding 1.51E-06 immune response-regulating signaling pathway 1.70E-06 response to endoplasmic reticulum stress 2.26E-06 organelle organization 2.53E-06 response to tumor necrosis factor 2.77E-06 regulation of proteolysis 2.94E-06 ribonucleoside triphosphate biosynthetic process 6.24E-06 protein folding 7.73E-06 regulation of mitotic cell cycle 1.12E-05 positive regulation of innate immune response 1.47E-05 nucleocytoplasmic transport 1.60E-05 cellular protein catabolic process 1.61E-05 ribosomal large subunit assembly 1.87E-05 "nucleotide-excision repair, DNA damage recognition " 1.87E-05 gene expression 1.97E-05 cell-cell signaling by wnt 1.99E-05 mitochondrial transport 2.21E-05 macromolecular complex disassembly 2.29E-05 generation of precursor metabolites and energy 2.72E-05 "nucleotide-excision repair, preincision complex assembly " 2.98E-05 protein monoubiquitination 3.25E-05 positive regulation of viral process 3.29E-05 activation of immune response 4.17E-05 translational elongation 4.19E-05 macroautophagy 4.62E-05 nitrogen compound metabolic process 5.54E-05 cellular macromolecule metabolic process 5.60E-05 multivesicular body assembly 6.71E-05 positive regulation of protein localization to Cajal body 7.82E-05 global genome nucleotide-excision repair 9.77E-05 ephrin receptor signaling pathway 0.000105833 "nucleotide-excision repair, DNA duplex unwinding " 0.000129044 protein targeting to ER 0.0001791 purine nucleoside monophosphate biosynthetic process 0.000219284 protein localization to nuclear body 0.000221222 Fc receptor signaling pathway 0.000222142 virion assembly 0.000241027 endoplasmic reticulum tubular network organization 0.000249967 regulation of Wnt signaling pathway 0.000259636 cytochrome complex assembly 0.000261665 regulation of mRNA metabolic process 0.000271833 cellular response to unfolded protein 0.000363697 cell surface receptor signaling pathway involved in cell-cell signaling 0.000461268 G2/M transition of mitotic cell cycle 0.000463447 maturation of LSU-rRNA 0.000478175 transcription-coupled nucleotide-excision repair 0.000485299 ER-associated ubiquitin-dependent protein catabolic process 0.000485299 "DNA damage response, detection of DNA damage " 0.000508866 cotranslational protein targeting to membrane 0.000594914 protein-DNA complex subunit organization 0.000610745 regulation of chromosome organization 0.000615638 RNA transport 0.000663273 purine nucleoside biosynthetic process 0.000702672 establishment of protein localization 0.000741317 IRE1-mediated unfolded protein response 0.000806003 Fc-gamma receptor signaling pathway involved in phagocytosis 0.000806003 cap-independent translational initiation 0.000832392 positive regulation of telomerase RNA localization to Cajal body 0.000832392 "regulation of symbiosis, encompassing mutualism through parasitism " 0.001023653 termination of RNA polymerase II transcription 0.001338258 RNA localization 0.001340703 RNA localization to Cajal body 0.001394609 telomerase RNA localization 0.001394609 regulation of protein metabolic process 0.001442581 negative regulation of translation 0.001471397 "regulation of gene expression, epigenetic " 0.00156549 endosomal transport 0.001814712 negative regulation of cellular protein metabolic process 0.001828891 ribonucleoprotein complex export from nucleus 0.001903469 ribonucleoside monophosphate biosynthetic process 0.00197449 DNA geometric change 0.00197449 regulation of protein dephosphorylation 0.00197449 protein folding in endoplasmic reticulum 0.002043116 protein localization to endoplasmic reticulum 0.00210049 cellular protein complex disassembly 0.002250826 RNA splicing 0.002343304 "vesicle targeting, to, from or within Golgi " 0.002358116 negative regulation of mRNA metabolic process 0.002383516 positive regulation of organelle organization 0.002406041 nucleobase-containing compound transport 0.002473492 substantia nigra development 0.002504191 negative regulation of catalytic activity 0.002685954 RNA-dependent DNA biosynthetic process 0.002703615 regulation of transferase activity 0.00304446 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) " 0.003104536 ribonucleoside biosynthetic process 0.003160401 exosomal secretion 0.003446319 telomere organization 0.003489009 Arp2/3 complex-mediated actin nucleation 0.003634986 regulation of organelle assembly 0.00391663 COPII vesicle coating 0.003946681 negative regulation of epidermal growth factor receptor signaling pathway 0.003967099 mRNA 3'-end processing 0.004269661 positive regulation of establishment of protein localization to telomere 0.004743118 positive regulation of viral genome replication 0.004821074 mRNA splice site selection 0.005359337 "mitochondrial electron transport, ubiquinol to cytochrome c " 0.005911858 proteasome assembly 0.005911858 positive regulation of viral release from host cell 0.005911858 regulation of type I interferon production 0.005957565 cellular ketone metabolic process 0.006060726 cellular response to organic substance 0.006105048 cellular process 0.006296665 positive regulation of telomere maintenance via telomerase 0.006313757 positive regulation of cellular protein localization 0.006420341 negative regulation of macromolecule metabolic process 0.00684737 protein stabilization 0.007179895 positive regulation of telomere maintenance 0.007492507 protein transmembrane transport 0.007949862 endosome organization 0.007962298 "regulation of alternative mRNA splicing, via spliceosome " 0.008172079 regulation of viral life cycle 0.008979992 "regulation of mRNA splicing, via spliceosome " 0.009309206 spliceosomal complex assembly 0.009339858 protein K11-linked ubiquitination 0.009760252 transcription elongation from RNA polymerase II promoter 0.009845556 negative regulation of macromolecule biosynthetic process 0.010068058 cell redox homeostasis 0.010390838 viral gene expression 0.010625277 histone H2A K63-linked deubiquitination 0.01067528 single-organism organelle organization 0.01086879 regulation of DNA-templated transcription in response to stress 0.011032673 positive regulation of translation 0.011219764 microtubule-based movement 0.011278579 organelle assembly 0.011575325 localization 0.011827438 cytokinesis 0.012322754 nucleus organization 0.012322754 glycosyl compound biosynthetic process 0.013081969 pore complex assembly 0.014040304 protein targeting to mitochondrion 0.014041111 RNA polymerase II transcriptional preinitiation complex assembly 0.014585408 response to unfolded protein 0.014913904 ER-nucleus signaling pathway 0.01528168 viral latency 0.015532655 regulation of establishment of protein localization to chromosome 0.015532655 regulation of cellular macromolecule biosynthetic process 0.016551323 histone ubiquitination 0.016643842 response to virus 0.017373041 monovalent inorganic cation transport 0.017587013 regulation of actin polymerization or depolymerization 0.018789224 negative regulation of nitrogen compound metabolic process 0.01928196 regulation of protein phosphatase type 2A activity 0.019768236 cell separation after cytokinesis 0.02047985 regulation of translational initiation in response to stress 0.02047985 negative regulation of cell death 0.020497341 toxin transport 0.020707221 IRES-dependent viral translational initiation 0.021115456 positive regulation of phosphorylation of RNA polymerase II C-terminal domain 0.021115456 negative regulation of RNA catabolic process 0.021115456 gene silencing by RNA 0.022507112 negative regulation of apoptotic process 0.02283965 proteasome-mediated ubiquitin-dependent protein catabolic process 0.025433855 negative regulation of RNA splicing 0.026314845 viral budding 0.026314845 multi-organism organelle organization 0.026314845 ATP hydrolysis coupled proton transport 0.027319128 cellular oxidant detoxification 0.027425992 cell cycle phase transition 0.027876567 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 0.028996615 regulation of defense response 0.029062907 mRNA export from nucleus 0.029510036 positive regulation of protein complex assembly 0.02982102 ribosomal small subunit biogenesis 0.029973194 gene silencing by miRNA 0.031532733 positive regulation of macromolecule metabolic process 0.033917663 establishment of organelle localization 0.033966797 DNA repair 0.034076411 multi-organism membrane organization 0.034320919 regulation of transcription from RNA polymerase II promoter in response to hypoxia 0.034320919 cytoskeleton-dependent intracellular transport 0.035587892 regulation of establishment of protein localization to mitochondrion 0.035587892 positive regulation of mitochondrion organization 0.037707144 regulation of protein polymerization 0.037707144 regulation of telomere maintenance via telomere lengthening 0.038479825 mitochondrial respiratory chain complex IV assembly 0.038660502 "regulation of protein localization to chromosome, telomeric region " 0.038660502 outer mitochondrial membrane organization 0.039999959 ribosome disassembly 0.039999959 mitochondrial respiratory chain complex III assembly 0.039999959 establishment of integrated proviral latency 0.039999959 regulation of proteasomal ubiquitin-dependent protein catabolic process 0.041046736 phosphorylation 0.044786688 mitochondrial translational termination 0.045032273 protein modification by small protein removal 0.047583429 establishment of chromosome localization 0.049963224 --------------------------------------------- "EP #2: 176 cells, 343 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0.0804597701149425, stage4: 0.2, St5_3_: 0.246575342465753, stage5_: 0.4375, stage6.2_: 0.414634146341463, stage6.7_: 0.407894736842105, stage6.14_: 0.656716417910448, " Top Genes: 2.776 CLU/ENSG00000120885.15 2.744 INS/ENSG00000254647.2 2.626 GCG/ENSG00000115263.10 2.244 SERPINI1/ENSG00000163536.8 2.166 ALDH1A1/ENSG00000165092.8 2.088 TTR/ENSG00000118271.5 2.05 HEPACAM2/ENSG00000188175.5 2.023 SCG5/ENSG00000166922.4 1.97 AGT/ENSG00000135744.7 1.968 SERPINA1/ENSG00000197249.8 1.918 ABCC8/ENSG00000006071.7 1.9 ISL1/ENSG00000016082.10 1.888 TMEM176B/ENSG00000106565.13 1.867 SLC30A8/ENSG00000164756.8 1.84 SPTSSB/ENSG00000196542.4 1.77 SEC11C/ENSG00000166562.4 1.746 FAM46A/ENSG00000112773.11 1.665 ASPH/ENSG00000198363.11 1.645 GAST/ENSG00000184502.3 1.594 AMBP/ENSG00000106927.7 1.585 AL590714.1/ENSG00000268387.1 1.573 CPE/ENSG00000109472.9 1.491 CDH18/ENSG00000145526.7 1.49 ERO1LB/ENSG00000086619.9 1.446 APOA2/ENSG00000158874.6 1.425 CAPN2/ENSG00000162909.13 1.413 FXYD2/ENSG00000137731.8 1.406 BTG1/ENSG00000133639.3 1.399 PYY/ENSG00000131096.6 1.398 SST/ENSG00000157005.3 1.371 PEMT/ENSG00000133027.13 1.34 SEBOX/ENSG00000109072.7 1.305 CHGA/ENSG00000100604.8 1.282 SPINK1/ENSG00000164266.6 1.277 CDH1/ENSG00000039068.13 1.273 GPX3/ENSG00000211445.6 1.27 GLUL/ENSG00000135821.11 1.269 F10/ENSG00000126218.7 1.235 ITGB1/ENSG00000150093.14 1.218 PRDX4/ENSG00000123131.8 1.206 REEP3/ENSG00000165476.8 1.203 PCP4/ENSG00000183036.6 1.199 KCNK16/ENSG00000095981.6 1.179 SMARCA2/ENSG00000080503.15 1.17 AC132217.4/ENSG00000240801.1 1.159 CRYBA2/ENSG00000163499.7 1.156 RGS4/ENSG00000117152.9 1.148 QPCT/ENSG00000115828.11 1.143 SAT1/ENSG00000130066.12 1.113 NAA20/ENSG00000173418.7 1.112 NUCB2/ENSG00000070081.10 1.1 ELL2/ENSG00000118985.10 1.097 GLS/ENSG00000115419.8 1.079 NPC2/ENSG00000119655.4 1.045 CTSB/ENSG00000164733.16 1.043 SCN7A/ENSG00000136546.9 1.021 PDK4/ENSG00000004799.7 1.007 DPP4/ENSG00000197635.5 1 CHGB/ENSG00000089199.5 1 SEZ6L/ENSG00000100095.14 0.974 PPY/ENSG00000108849.3 0.972 PAX6/ENSG00000007372.15 0.971 TIMP1/ENSG00000102265.7 0.967 RPS6KA3/ENSG00000177189.8 0.965 SMC2/ENSG00000136824.14 0.946 TSTD1/ENSG00000215845.6 0.916 FKBP11/ENSG00000134285.6 0.915 GRB14/ENSG00000115290.5 0.914 MOB1B/ENSG00000173542.4 0.911 TMED4/ENSG00000158604.10 0.906 PLK2/ENSG00000145632.10 0.903 TMEM176A/ENSG00000002933.3 0.889 CDC42EP3/ENSG00000163171.6 0.873 KIAA1244/ENSG00000112379.8 0.858 REXO2/ENSG00000076043.5 0.83 PDIA6/ENSG00000143870.8 0.827 FBXW7/ENSG00000109670.9 0.814 MPC2/ENSG00000143158.6 0.805 MAGI2-AS3/ENSG00000234456.2 0.804 FKBP2/ENSG00000173486.8 0.803 RFX6/ENSG00000185002.5 0.799 CST3/ENSG00000101439.4 0.769 SLC7A8/ENSG00000092068.14 0.768 TMEM45B/ENSG00000151715.3 0.764 B2M/ENSG00000166710.12 0.76 IGF2/ENSG00000167244.12 0.757 ETV1/ENSG00000006468.9 0.757 AKAP12/ENSG00000131016.12 0.756 RAD21/ENSG00000164754.8 0.754 CTD-2290C23.1/ENSG00000224282.3 0.745 TMEM59/ENSG00000116209.7 0.74 GPR119/ENSG00000147262.2 0.737 FGD4/ENSG00000139132.10 0.734 PPAPDC1B/ENSG00000147535.12 0.723 MYH10/ENSG00000133026.8 0.707 ETFDH/ENSG00000171503.7 0.704 XBP1/ENSG00000100219.12 0.701 SCGN/ENSG00000079689.9 0.694 CD59/ENSG00000085063.10 0.687 NEFM/ENSG00000104722.9 0.685 HERPUD1/ENSG00000051108.10 0.677 DPYSL2/ENSG00000092964.11 0.664 C10ORF10/ENSG00000165507.8 0.651 CD46/ENSG00000117335.14 0.65 ESYT1/ENSG00000139641.8 0.649 LOXL4/ENSG00000138131.3 0.649 IMMP1L/ENSG00000148950.5 0.643 APOC3/ENSG00000110245.7 0.634 SEC61G/ENSG00000132432.9 0.625 IQGAP2/ENSG00000145703.11 0.62 ASAH1/ENSG00000104763.13 0.618 SPINT2/ENSG00000167642.8 0.617 C12ORF75/ENSG00000235162.4 0.614 C12ORF57/ENSG00000111678.5 0.606 DSP/ENSG00000096696.9 0.605 AFP/ENSG00000081051.3 0.603 ITM2B/ENSG00000136156.7 0.603 AC040977.1/ENSG00000269871.1 0.6 CD164/ENSG00000135535.10 0.599 VPS13C/ENSG00000129003.11 0.593 SPOCK3/ENSG00000196104.6 0.59 CACNB2/ENSG00000165995.14 0.587 MBOAT2/ENSG00000143797.7 0.584 GS1-358P8.4/ENSG00000260822.1 0.581 RPN2/ENSG00000118705.12 0.578 HIGD1A/ENSG00000181061.9 0.577 GRIA3/ENSG00000125675.13 0.574 "AC011897.1,FAM84A/ENSG00000162981.12" 0.57 PDZK1/ENSG00000174827.9 0.569 NR3C1/ENSG00000113580.10 0.563 EGFEM1P/ENSG00000206120.7 0.562 NEBL/ENSG00000078114.14 0.56 TSTD2/ENSG00000136925.10 0.556 VSTM2A/ENSG00000170419.6 0.555 BEX5/ENSG00000184515.6 0.555 MGST3/ENSG00000143198.7 0.554 SPATS2L/ENSG00000196141.7 0.55 TMED3/ENSG00000166557.8 0.55 ATP6AP2/ENSG00000182220.9 0.547 LINC00261/ENSG00000259974.1 0.546 PLD3/ENSG00000105223.14 0.543 MAFB/ENSG00000204103.2 0.542 CYSTM1/ENSG00000120306.5 0.537 PDK3/ENSG00000067992.8 0.537 MAN1A1/ENSG00000111885.5 0.533 APOC1/ENSG00000130208.5 0.528 CD63/ENSG00000135404.7 0.527 SLC7A2/ENSG00000003989.12 0.526 AC090627.1/ENSG00000235300.3 0.526 CTD-2003C8.1/ENSG00000247271.2 0.525 HPS1/ENSG00000107521.14 0.523 WIPI1/ENSG00000070540.8 0.522 GULP1/ENSG00000144366.11 0.521 LDB2/ENSG00000169744.8 0.517 KRT19/ENSG00000171345.9 0.516 SUMF2/ENSG00000129103.13 0.515 DAAM1/ENSG00000100592.11 0.514 SLC39A9/ENSG00000029364.7 0.512 USH1C/ENSG00000006611.10 0.509 HSPA5/ENSG00000044574.7 0.509 TMED2/ENSG00000086598.6 0.508 FXYD3/ENSG00000089356.12 0.508 SCD/ENSG00000099194.5 0.506 LAMP2/ENSG00000005893.11 0.506 DMKN/ENSG00000161249.16 0.505 PDXDC1/ENSG00000179889.14 0.505 RSBN1L-AS1/ENSG00000214293.4 0.503 PCSK2/ENSG00000125851.5 0.501 GNAI1/ENSG00000127955.11 0.498 SH3YL1/ENSG00000035115.17 0.496 CBFB/ENSG00000067955.9 0.496 GCH1/ENSG00000131979.14 0.493 TMEM147/ENSG00000105677.7 0.49 ATP2B1/ENSG00000070961.10 0.488 GHRL/ENSG00000157017.11 0.487 PIGT/ENSG00000124155.11 0.487 FAM174B/ENSG00000185442.7 0.483 VIM/ENSG00000026025.9 0.48 SYNE1/ENSG00000131018.17 0.478 ATP1B1/ENSG00000143153.7 0.476 ANXA4/ENSG00000196975.9 0.473 DPM3/ENSG00000179085.7 0.473 RBMX2/ENSG00000134597.9 0.472 PPP1R1A/ENSG00000135447.12 0.47 VLDLR/ENSG00000147852.10 0.47 ALCAM/ENSG00000170017.8 0.468 MANBA/ENSG00000109323.4 0.466 GPX7/ENSG00000116157.5 0.465 CAPZB/ENSG00000077549.13 0.463 LDHA/ENSG00000134333.9 0.463 MCFD2/ENSG00000180398.7 0.462 LRPAP1/ENSG00000163956.6 0.462 IFI27L2/ENSG00000119632.3 0.461 CADM1/ENSG00000182985.11 0.46 SLC29A1/ENSG00000112759.12 0.46 MDK/ENSG00000110492.11 0.458 TSC22D1/ENSG00000102804.10 0.455 PPIB/ENSG00000166794.4 0.453 KCNK17/ENSG00000124780.9 0.453 C14ORF105/ENSG00000100557.5 0.451 NT5DC3/ENSG00000111696.7 0.451 SAR1B/ENSG00000152700.9 0.45 MGST2/ENSG00000085871.4 0.448 S100A6/ENSG00000197956.5 0.447 PALLD/ENSG00000129116.13 0.446 TFF3/ENSG00000160180.14 0.436 PLP2/ENSG00000102007.6 0.433 PRKAR1A/ENSG00000108946.8 0.431 RP11-1100L3.8/ENSG00000259884.1 0.43 ACVR1C/ENSG00000123612.10 0.429 CDC42SE2/ENSG00000158985.9 0.429 COX17/ENSG00000138495.2 0.429 MEIS1/ENSG00000143995.14 0.427 TSPAN1/ENSG00000117472.5 0.426 PARM1/ENSG00000169116.7 0.426 VWA5A/ENSG00000110002.11 0.426 RP11-101E14.2/ENSG00000237767.1 0.425 NOSTRIN/ENSG00000163072.10 0.424 TMOD1/ENSG00000136842.8 0.422 TNFSF10/ENSG00000121858.6 0.421 SSTR2/ENSG00000180616.4 0.418 KCNMA1/ENSG00000156113.16 0.418 NR0B2/ENSG00000131910.4 0.417 GC/ENSG00000145321.8 0.417 CACUL1/ENSG00000151893.10 0.416 HM13/ENSG00000101294.12 0.415 CALM1/ENSG00000198668.6 0.414 RP11-16E23.4/ENSG00000259924.1 0.412 CHKA/ENSG00000110721.7 0.41 U47924.27/ENSG00000257084.1 0.408 SSR4/ENSG00000180879.8 0.408 CNIH4/ENSG00000143771.7 0.402 NEDD4L/ENSG00000049759.12 0.4 DUSP1/ENSG00000120129.5 0.393 CHST9/ENSG00000154080.8 0.393 SRPRB/ENSG00000144867.6 0.387 APOA1/ENSG00000118137.5 0.387 COX8A/ENSG00000176340.3 0.387 EDEM1/ENSG00000134109.6 0.382 LBH/ENSG00000213626.7 0.38 ABCD3/ENSG00000117528.7 0.38 TMEM14A/ENSG00000096092.5 0.378 ZDHHC8P1/ENSG00000133519.8 0.376 CLIP4/ENSG00000115295.15 0.375 GPATCH8/ENSG00000186566.7 0.374 ARX/ENSG00000004848.6 0.371 RP11-1143G9.4/ENSG00000257764.2 0.37 ELP4/ENSG00000109911.13 0.368 EXOSC7/ENSG00000075914.8 0.365 MGST1/ENSG00000008394.7 0.365 DNAJC3/ENSG00000102580.10 0.359 C11ORF1/ENSG00000137720.3 0.359 KCTD3/ENSG00000136636.8 0.358 PDE3B/ENSG00000152270.4 0.358 SYT4/ENSG00000132872.7 0.357 CXCL1/ENSG00000163739.4 0.357 CD81/ENSG00000110651.7 0.356 RABAC1/ENSG00000105404.6 0.355 GLYATL1P2/ENSG00000254717.2 0.352 HINT1/ENSG00000169567.7 0.35 FGFR1/ENSG00000077782.15 0.347 NCALD/ENSG00000104490.13 0.345 ABLIM1/ENSG00000099204.14 0.344 COX5A/ENSG00000178741.7 0.342 LGALSL/ENSG00000119862.7 0.341 MYO3A/ENSG00000095777.10 0.341 PEG10/ENSG00000242265.1 0.339 TUSC3/ENSG00000104723.16 0.339 RASSF4/ENSG00000107551.15 0.339 SH3KBP1/ENSG00000147010.13 0.334 DAPK1-IT1/ENSG00000236709.1 0.333 P4HB/ENSG00000185624.9 0.325 DHRS7/ENSG00000100612.9 0.324 CTD-2545M3.2/ENSG00000268854.1 0.323 PSAP/ENSG00000197746.9 0.323 NRXN3/ENSG00000021645.13 0.323 ERP29/ENSG00000089248.6 0.323 LPAR1/ENSG00000198121.9 0.323 P4HA2/ENSG00000072682.13 0.322 ASAP1/ENSG00000153317.10 0.321 ATP5E/ENSG00000124172.5 0.32 TSPAN2/ENSG00000134198.5 0.32 COA6/ENSG00000168275.10 0.32 NRCAM/ENSG00000091129.15 0.318 LRP11/ENSG00000120256.4 0.318 SELK/ENSG00000113811.6 0.316 SDC2/ENSG00000169439.7 0.315 SNX29/ENSG00000048471.9 0.313 MYO1B/ENSG00000128641.13 0.309 IFI6/ENSG00000126709.10 0.308 JTB/ENSG00000143543.10 0.306 SCARNA22/ENSG00000249784.1 0.306 DCC/ENSG00000187323.7 0.305 HMGN3/ENSG00000118418.10 0.304 FAM214A/ENSG00000047346.8 0.304 SNAP25/ENSG00000132639.8 0.304 SLC14A1/ENSG00000141469.12 0.304 FN1/ENSG00000115414.14 0.303 HSD17B14/ENSG00000087076.4 0.302 APCDD1/ENSG00000154856.7 0.302 RP11-379K17.12/ENSG00000268220.1 0.301 MAN2A1/ENSG00000112893.5 0.301 PAM/ENSG00000145730.16 0.299 CTNND2/ENSG00000169862.14 0.298 PCSK1N/ENSG00000102109.6 0.294 IDH2/ENSG00000182054.5 0.293 PHTF2/ENSG00000006576.12 0.293 LPPR5/ENSG00000117598.7 0.292 VCL/ENSG00000035403.12 0.291 HEXB/ENSG00000049860.9 0.29 SSR3/ENSG00000114850.2 0.29 MYO10/ENSG00000145555.10 0.288 MLN/ENSG00000096395.6 0.287 SH3BP5/ENSG00000131370.11 0.286 MAOA/ENSG00000189221.5 0.285 SLC12A2/ENSG00000064651.9 0.283 TMSB15B/ENSG00000158427.10 0.283 GRIA4/ENSG00000152578.8 0.281 CEACAM1/ENSG00000079385.17 0.277 NEAT1/ENSG00000245532.3 0.276 CD74/ENSG00000019582.10 0.274 FOS/ENSG00000170345.5 0.273 RP11-499P20.2/ENSG00000240291.1 0.273 TTC8/ENSG00000165533.14 0.272 FHL1/ENSG00000022267.12 0.272 RCN1/ENSG00000049449.4 0.27 FNDC3A/ENSG00000102531.12 0.268 RNASEK/ENSG00000219200.5 0.268 MAP2/ENSG00000078018.15 0.267 CD55/ENSG00000196352.9 0.263 CSGALNACT1/ENSG00000147408.10 0.261 RP11-5N11.5/ENSG00000248378.1 0.26 AGA/ENSG00000038002.4 0.26 ANXA7/ENSG00000138279.10 0.259 APOM/ENSG00000204444.6 0.257 MMP16/ENSG00000156103.11 0.257 LCLAT1/ENSG00000172954.9 0.256 ZNF608/ENSG00000168916.10 0.255 SEPP1/ENSG00000250722.1 0.255 B3GNT7/ENSG00000156966.6 0.254 NDUFB1/ENSG00000183648.4 0.253 KLF10/ENSG00000155090.10 0.252 MTMR7/ENSG00000003987.9 Overrepresented GO terms in EP #2: Term Pvalue response to oxygen-containing compound 1.27E-06 establishment of localization 1.58E-06 platelet degranulation 4.50E-06 regulation of biological quality 7.45E-06 single-organism process 1.48E-05 single-organism localization 1.66E-05 protein-lipid complex remodeling 0.000120154 response to glucose 0.000180811 regulation of secretion by cell 0.000233802 negative regulation of proteolysis 0.000254108 high-density lipoprotein particle remodeling 0.000274858 negative regulation of very-low-density lipoprotein particle remodeling 0.000279583 insulin processing 0.000279583 response to monosaccharide 0.000314047 regulation of plasma lipoprotein particle levels 0.000324311 positive regulation of cholesterol esterification 0.000361413 chemical homeostasis 0.000364338 reverse cholesterol transport 0.000393312 signaling 0.000577474 high-density lipoprotein particle clearance 0.000640366 negative regulation of protein secretion 0.000740621 neuron projection development 0.000863739 regulation of catalytic activity 0.00087239 response to external stimulus 0.000940502 regulation of peptide transport 0.001088845 negative regulation of very-low-density lipoprotein particle clearance 0.001101834 cellular lipid metabolic process 0.001234019 plasma lipoprotein particle organization 0.001234548 protein processing 0.001265947 negative regulation of lipid catabolic process 0.001307773 secretion 0.001321251 positive regulation of insulin secretion 0.001340562 negative regulation of secretion 0.001440293 negative regulation of molecular function 0.001497951 regulation of cardiac conduction 0.001502691 hormone transport 0.001521509 central nervous system development 0.001625425 IRE1-mediated unfolded protein response 0.00168086 protein-lipid complex assembly 0.001688683 response to nutrient levels 0.001746038 positive regulation of peptide secretion 0.001852903 positive regulation of hormone secretion 0.002062299 negative regulation of endopeptidase activity 0.002117985 locomotion 0.002534279 amide transport 0.002595782 movement of cell or subcellular component 0.003039725 regulation of peptide hormone secretion 0.003224226 phospholipid efflux 0.003412025 sterol esterification 0.003412025 response to organonitrogen compound 0.003498021 cholesterol efflux 0.003955048 response to corticosteroid 0.004523431 negative regulation of lipase activity 0.004702331 import into cell 0.005176084 cellular oxidant detoxification 0.006673679 localization of cell 0.007342865 regulation of localization 0.007531929 cell migration 0.008357729 multicellular organismal signaling 0.008389336 lipid transport 0.009063334 signal release 0.009090022 regulation of peptidase activity 0.00916705 ion transport 0.009672111 protein folding 0.009799626 regulation of cell shape 0.010294156 regulation of cellular component organization 0.010369667 response to hormone 0.01052747 detoxification 0.011024645 single-organism carbohydrate metabolic process 0.011362231 organic hydroxy compound transport 0.011382747 lipoprotein metabolic process 0.011632265 regulation of fatty acid biosynthetic process 0.011983048 protein localization 0.012413866 feeding behavior 0.012906526 lysine import 0.014165232 negative regulation of cholesterol import 0.014165232 L-arginine import into cell 0.014165232 L-lysine import into cell 0.014165232 exocytosis 0.01416802 cellular homeostasis 0.015682232 myofibril assembly 0.016043454 positive regulation of nitric-oxide synthase activity 0.016834234 response to corticosterone 0.016834234 animal organ development 0.017272298 multicellular organism development 0.017604923 hormone metabolic process 0.01848627 negative regulation of hydrolase activity 0.018501903 regulation of protein transport 0.019630157 high-density lipoprotein particle assembly 0.021485852 vesicle-mediated transport 0.022634089 regulation of lipid metabolic process 0.023165753 signal transduction 0.025140973 cellular component organization or biogenesis 0.026019986 small molecule metabolic process 0.027593776 positive regulation of transport 0.028458809 single-organism catabolic process 0.029374466 negative regulation of sterol transport 0.030243822 triglyceride-rich lipoprotein particle remodeling 0.030243822 regulation of high voltage-gated calcium channel activity 0.030243822 signal peptide processing 0.030313456 extracellular matrix disassembly 0.032453794 organophosphate metabolic process 0.033772207 cellular response to unfolded protein 0.035203439 response to cold 0.035669316 protein deglycosylation 0.036126218 negative regulation of fatty acid metabolic process 0.036126218 muscle contraction 0.036172861 cell morphogenesis 0.036238331 regulation of protein stability 0.036921745 extracellular structure organization 0.038668492 positive regulation of protein kinase activity 0.039163634 regulation of multicellular organismal process 0.04010062 lipid biosynthetic process 0.040471954 retinoid metabolic process 0.04061337 response to lipid hydroperoxide 0.041936529 regulation of collagen catabolic process 0.041936529 regulation of sterol import 0.041936529 phosphatidylcholine metabolic process 0.04282932 multi-multicellular organism process 0.044983416 regulation of kinase activity 0.047674224 oxidation-reduction process 0.047692584 developmental process 0.04863464 --------------------------------------------- "EP #3: 773 cells, 1234 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 1, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 1, St5_3_: 1, stage5_: 1, stage6.2_: 1, stage6.7_: 1, stage6.14_: 1, " Top Genes: 2.326 SNRPD1/ENSG00000167088.5 2.289 UBE2N/ENSG00000177889.5 2.259 PRDX1/ENSG00000117450.9 2.251 IDH1/ENSG00000138413.9 2.113 TUBB/ENSG00000196230.8 2.074 NME1/ENSG00000239672.3 2.025 PRDX6/ENSG00000117592.8 2.012 XRCC6/ENSG00000196419.8 1.989 ILF2/ENSG00000143621.12 1.916 HNRNPD/ENSG00000138668.14 1.898 "NME1-NME2,NME2/ENSG00000011052.16" 1.861 APEX1/ENSG00000100823.7 1.841 SRSF7/ENSG00000115875.14 1.794 FAM60A/ENSG00000139146.9 1.789 HSD17B4/ENSG00000133835.10 1.784 EIF3M/ENSG00000149100.8 1.782 CCT5/ENSG00000150753.7 1.777 CDC123/ENSG00000151465.9 1.744 HDAC2/ENSG00000196591.7 1.711 SNHG5/ENSG00000203875.5 1.706 NOP58/ENSG00000055044.6 1.691 SRI/ENSG00000075142.9 1.686 RSL1D1/ENSG00000171490.8 1.683 HMGN1/ENSG00000205581.6 1.683 LARS/ENSG00000133706.13 1.662 CLNS1A/ENSG00000074201.3 1.652 CCNG1/ENSG00000113328.14 1.65 G3BP1/ENSG00000145907.10 1.649 FDPS/ENSG00000160752.10 1.636 HSPE1/ENSG00000115541.6 1.625 SNRPF/ENSG00000139343.6 1.621 PDHB/ENSG00000168291.8 1.621 CACYBP/ENSG00000116161.13 1.621 VDAC1/ENSG00000213585.6 1.62 FKBP3/ENSG00000100442.6 1.619 CNBP/ENSG00000169714.12 1.612 EXOSC8/ENSG00000120699.8 1.611 GPI/ENSG00000105220.9 1.609 PAFAH1B2/ENSG00000168092.9 1.604 RBMX/ENSG00000147274.10 1.601 PDHA1/ENSG00000131828.9 1.6 AHCY/ENSG00000101444.7 1.596 MRPL51/ENSG00000111639.3 1.595 PTGES3/ENSG00000110958.11 1.594 SSB/ENSG00000138385.11 1.582 BANF1/ENSG00000175334.3 1.58 THYN1/ENSG00000151500.10 1.579 PSMA5/ENSG00000143106.8 1.572 IMPDH2/ENSG00000178035.7 1.568 NCL/ENSG00000115053.11 1.563 NDUFA4/ENSG00000189043.5 1.563 CKS2/ENSG00000123975.4 1.562 CCT4/ENSG00000115484.10 1.559 SNRPE/ENSG00000182004.8 1.557 PEBP1/ENSG00000089220.4 1.553 HSPD1/ENSG00000144381.12 1.552 LSM12/ENSG00000161654.5 1.547 SNRPA1/ENSG00000131876.12 1.539 TUBA1B/ENSG00000123416.11 1.538 EIF4A1/ENSG00000161960.10 1.532 TRMT112/ENSG00000173113.2 1.531 SF3A3/ENSG00000183431.7 1.522 ZNF121/ENSG00000197961.6 1.518 MRPL13/ENSG00000172172.3 1.514 AKR1A1/ENSG00000117448.9 1.511 RBBP4/ENSG00000162521.13 1.506 HNRNPF/ENSG00000169813.12 1.505 LSM5/ENSG00000106355.5 1.503 COA1/ENSG00000106603.13 1.491 ENO1/ENSG00000074800.9 1.489 SARNP/ENSG00000205323.4 1.479 PAICS/ENSG00000128050.4 1.479 CNIH4/ENSG00000143771.7 1.475 SUMO1/ENSG00000116030.12 1.472 EIF4E/ENSG00000151247.8 1.472 SNHG1/ENSG00000255717.1 1.468 MRPL42/ENSG00000198015.8 1.457 TCERG1/ENSG00000113649.7 1.448 ADH5/ENSG00000197894.6 1.447 MTPAP/ENSG00000107951.7 1.441 RPN2/ENSG00000118705.12 1.441 MRPL39/ENSG00000154719.9 1.433 COPS8/ENSG00000198612.6 1.432 PSMA4/ENSG00000041357.11 1.426 HMGB3/ENSG00000029993.10 1.419 GNL3/ENSG00000163938.12 1.419 PABPC1/ENSG00000070756.9 1.416 NHP2/ENSG00000145912.4 1.416 RPS9/ENSG00000170889.9 1.415 UBE2V2/ENSG00000169139.7 1.411 PGD/ENSG00000142657.16 1.409 MMADHC/ENSG00000168288.8 1.398 EIF2S1/ENSG00000134001.8 1.398 DGUOK/ENSG00000114956.15 1.394 NAE1/ENSG00000159593.10 1.388 TOMM5/ENSG00000175768.8 1.386 CCT7/ENSG00000135624.11 1.38 PCNP/ENSG00000081154.7 1.378 PA2G4/ENSG00000170515.9 1.378 PSMD14/ENSG00000115233.7 1.377 BZW1/ENSG00000082153.13 1.374 NUDT5/ENSG00000165609.8 1.373 CYCS/ENSG00000172115.4 1.372 CFDP1/ENSG00000153774.4 1.369 GAS5/ENSG00000234741.2 1.363 TCEB1/ENSG00000154582.12 1.359 PSMC5/ENSG00000087191.8 1.353 THRAP3/ENSG00000054118.9 1.348 GLRX3/ENSG00000108010.7 1.343 TPM3/ENSG00000143549.14 1.342 TAF9/ENSG00000085231.9 1.339 SSBP1/ENSG00000106028.6 1.337 CCT8/ENSG00000156261.8 1.332 EIF3I/ENSG00000084623.7 1.327 EIF3E/ENSG00000104408.5 1.325 NASP/ENSG00000132780.12 1.322 POLR2I/ENSG00000105258.4 1.321 SNRPD3/ENSG00000100028.7 1.321 TMEM167A/ENSG00000174695.5 1.318 SERBP1/ENSG00000142864.10 1.314 ATIC/ENSG00000138363.10 1.311 C14ORF166/ENSG00000087302.4 1.304 ANKRD10/ENSG00000088448.10 1.302 STIP1/ENSG00000168439.12 1.298 NOP56/ENSG00000101361.10 1.296 SDCBP/ENSG00000137575.7 1.296 TAF1D/ENSG00000166012.10 1.294 BCCIP/ENSG00000107949.12 1.291 PHB/ENSG00000167085.6 1.289 PAIP2/ENSG00000120727.6 1.287 RPS4Y1/ENSG00000129824.9 1.286 RAN/ENSG00000132341.6 1.285 PPA1/ENSG00000180817.6 1.285 U2SURP/ENSG00000163714.12 1.282 EIF3K/ENSG00000178982.5 1.281 C11ORF48/ENSG00000162194.8 1.28 SRRM1/ENSG00000133226.12 1.276 SH3D19/ENSG00000109686.12 1.274 GLO1/ENSG00000124767.6 1.274 MRPL21/ENSG00000197345.8 1.268 TXN/ENSG00000136810.8 1.266 SNHG6/ENSG00000245910.3 1.265 MEA1/ENSG00000124733.3 1.262 AKR1B1/ENSG00000085662.9 1.261 HNRNPK/ENSG00000165119.14 1.259 SUMO2/ENSG00000188612.7 1.256 DDX47/ENSG00000213782.3 1.253 DANCR/ENSG00000226950.2 1.249 S100A11/ENSG00000163191.5 1.242 ANP32E/ENSG00000143401.10 1.234 HN1/ENSG00000189159.11 1.227 TALDO1/ENSG00000177156.6 1.226 STOML2/ENSG00000165283.11 1.218 FAM136A/ENSG00000035141.3 1.215 PSMD11/ENSG00000108671.5 1.215 SNHG16/ENSG00000163597.9 1.209 PCMT1/ENSG00000120265.12 1.208 SNRPC/ENSG00000124562.5 1.204 IARS/ENSG00000196305.13 1.203 HBS1L/ENSG00000112339.10 1.203 CAMTA1/ENSG00000171735.14 1.2 HNRNPU/ENSG00000153187.12 1.196 ZNF207/ENSG00000010244.12 1.195 ADSL/ENSG00000239900.6 1.195 TARS/ENSG00000113407.9 1.194 SDHD/ENSG00000204370.4 1.188 SUPT16H/ENSG00000092201.5 1.187 UQCRH/ENSG00000173660.7 1.186 DHX15/ENSG00000109606.8 1.185 PPT1/ENSG00000131238.11 1.182 PSMA6/ENSG00000100902.6 1.181 PRPF40A/ENSG00000196504.11 1.181 FDFT1/ENSG00000079459.8 1.178 LSM6/ENSG00000164167.5 1.176 TCP1/ENSG00000120438.7 1.176 NUTF2/ENSG00000102898.6 1.172 APRT/ENSG00000198931.6 1.17 PARP1/ENSG00000143799.8 1.169 HSPA9/ENSG00000113013.8 1.166 DLD/ENSG00000091140.8 1.162 DRG1/ENSG00000185721.7 1.147 C12ORF57/ENSG00000111678.5 1.142 COPS3/ENSG00000141030.8 1.142 TIMM23/ENSG00000138297.9 1.14 RPS4X/ENSG00000198034.6 1.139 PSMD4/ENSG00000159352.10 1.136 MRPL52/ENSG00000172590.14 1.133 RPP21/ENSG00000241370.1 1.133 PHAX/ENSG00000164902.9 1.129 BTF3/ENSG00000145741.11 1.127 EXOSC7/ENSG00000075914.8 1.119 SRSF2/ENSG00000161547.10 1.116 DAP3/ENSG00000132676.10 1.113 LAPTM4A/ENSG00000068697.6 1.113 C11ORF73/ENSG00000149196.11 1.107 PHF20/ENSG00000025293.11 1.106 SNRPB2/ENSG00000125870.6 1.104 BZW2/ENSG00000136261.10 1.103 NDUFS4/ENSG00000164258.7 1.102 NOLC1/ENSG00000166197.12 1.099 PDIA6/ENSG00000143870.8 1.098 MRPL3/ENSG00000114686.4 1.097 MRPS7/ENSG00000125445.6 1.097 TRIAP1/ENSG00000170855.3 1.096 DNAJC8/ENSG00000126698.6 1.095 CCT6A/ENSG00000146731.6 1.094 ALDOA/ENSG00000149925.12 1.093 UBE2G1/ENSG00000132388.8 1.092 GNPDA1/ENSG00000113552.11 1.088 C4ORF27/ENSG00000056050.6 1.087 ST13/ENSG00000100380.8 1.087 EIF3H/ENSG00000147677.6 1.082 VBP1/ENSG00000155959.6 1.078 TOMM6/ENSG00000214736.3 1.076 SAE1/ENSG00000142230.7 1.074 GPBP1/ENSG00000062194.11 1.074 STARD7/ENSG00000084090.9 1.071 MRPL47/ENSG00000136522.9 1.07 CALU/ENSG00000128595.12 1.069 MTF2/ENSG00000143033.13 1.069 NCBP2/ENSG00000114503.6 1.068 MRPL15/ENSG00000137547.4 1.067 CCT3/ENSG00000163468.9 1.066 TMED2/ENSG00000086598.6 1.063 TIMM10/ENSG00000134809.4 1.061 EIF3D/ENSG00000100353.13 1.06 EIF4E2/ENSG00000135930.9 1.059 SYPL1/ENSG00000008282.3 1.058 AZIN1/ENSG00000155096.8 1.055 XPO1/ENSG00000082898.12 1.049 DKC1/ENSG00000130826.11 1.049 BROX/ENSG00000162819.7 1.048 SRP72/ENSG00000174780.11 1.045 SYNCRIP/ENSG00000135316.12 1.045 CTB-43P18.1/ENSG00000249758.1 1.045 BUB3/ENSG00000154473.13 1.044 POLR2F/ENSG00000100142.8 1.044 SEC11A/ENSG00000140612.9 1.044 UQCRC2/ENSG00000140740.6 1.043 PNRC2/ENSG00000189266.7 1.043 EEF1E1/ENSG00000124802.7 1.041 OLA1/ENSG00000138430.11 1.04 WDR12/ENSG00000138442.4 1.039 MYL6B/ENSG00000196465.5 1.035 TOMM22/ENSG00000100216.4 1.034 NARS/ENSG00000134440.7 1.034 PSMA3/ENSG00000100567.8 1.031 LYPLA1/ENSG00000120992.13 1.028 SMS/ENSG00000102172.11 1.028 GPN1/ENSG00000198522.8 1.027 PPP2R1A/ENSG00000105568.13 1.025 ERH/ENSG00000100632.6 1.024 METAP2/ENSG00000111142.9 1.024 POLR2K/ENSG00000147669.6 1.023 HNRNPH3/ENSG00000096746.13 1.022 EIF1AX/ENSG00000173674.6 1.02 TPRKB/ENSG00000144034.10 1.018 GNL2/ENSG00000134697.7 1.018 AEBP2/ENSG00000139154.10 1.017 PSMB2/ENSG00000126067.7 1.017 PSMA2/ENSG00000106588.6 1.013 RP11-742N3.1/ENSG00000227097.4 1.012 PSMC3/ENSG00000165916.4 1.01 KPNA2/ENSG00000182481.4 1.009 HIF1A/ENSG00000100644.12 1.006 MRPL45/ENSG00000174100.5 1.003 ARF4/ENSG00000168374.6 1.003 SNX5/ENSG00000089006.11 0.999 CSE1L/ENSG00000124207.12 0.992 UROD/ENSG00000126088.8 0.992 SF3B5/ENSG00000169976.5 0.988 SCD/ENSG00000099194.5 0.986 CBX3/ENSG00000122565.14 0.985 SUCLA2/ENSG00000136143.9 0.985 DDX3X/ENSG00000215301.5 0.985 CNOT2/ENSG00000111596.7 0.983 CSNK2A1/ENSG00000101266.11 0.98 SMARCE1/ENSG00000073584.14 0.977 PSMD2/ENSG00000175166.12 0.977 CHCHD3/ENSG00000106554.7 0.976 C14ORF119/ENSG00000179933.4 0.974 CCT2/ENSG00000166226.7 0.969 NOL11/ENSG00000130935.5 0.967 ITGAE/ENSG00000083457.7 0.966 THOC7/ENSG00000163634.7 0.965 TIMM13/ENSG00000099800.3 0.963 GART/ENSG00000159131.12 0.963 CNOT1/ENSG00000125107.12 0.962 TARDBP/ENSG00000120948.11 0.961 MAPRE1/ENSG00000101367.8 0.956 VDAC2/ENSG00000165637.9 0.955 RAD21/ENSG00000164754.8 0.952 PGK1/ENSG00000102144.9 0.946 IPO5/ENSG00000065150.14 0.942 UCHL3/ENSG00000118939.12 0.942 ECHS1/ENSG00000127884.4 0.942 PTGR1/ENSG00000106853.12 0.941 VTA1/ENSG00000009844.10 0.938 CAPRIN1/ENSG00000135387.15 0.936 TRA2B/ENSG00000136527.13 0.934 FKBP1A/ENSG00000088832.10 0.934 ZCCHC17/ENSG00000121766.10 0.934 PSME2/ENSG00000100911.9 0.931 FIBP/ENSG00000172500.8 0.928 HAUS1/ENSG00000152240.8 0.927 PPIL1/ENSG00000137168.7 0.925 DNTTIP2/ENSG00000067334.9 0.922 NAA15/ENSG00000164134.8 0.921 M6PR/ENSG00000003056.3 0.919 LCMT1/ENSG00000205629.7 0.919 ING3/ENSG00000071243.11 0.917 RPA2/ENSG00000117748.5 0.915 UBA3/ENSG00000144744.12 0.912 QARS/ENSG00000172053.10 0.912 AHSA1/ENSG00000100591.3 0.908 ATXN10/ENSG00000130638.11 0.907 TMEM14B/ENSG00000137210.8 0.903 BCAS2/ENSG00000116752.5 0.903 YWHAQ/ENSG00000134308.9 0.903 UFD1L/ENSG00000070010.13 0.903 PPP1CA/ENSG00000172531.10 0.901 HLTF/ENSG00000071794.11 0.899 MRPS23/ENSG00000181610.8 0.899 CDK7/ENSG00000134058.6 0.899 LDHA/ENSG00000134333.9 0.898 C6ORF211/ENSG00000146476.6 0.898 RPL22L1/ENSG00000163584.13 0.896 SF3B3/ENSG00000189091.8 0.895 API5/ENSG00000166181.8 0.895 SS18L2/ENSG00000008324.6 0.895 BAG4/ENSG00000156735.6 0.895 ELP2/ENSG00000134759.9 0.894 UTP6/ENSG00000108651.5 0.893 TSN/ENSG00000211460.7 0.893 RP11-973H7.2/ENSG00000267411.1 0.892 PAPSS1/ENSG00000138801.4 0.891 CIAPIN1/ENSG00000005194.10 0.891 PRKDC/ENSG00000253729.3 0.89 PDCD10/ENSG00000114209.10 0.89 OAZ1/ENSG00000104904.7 0.889 CLDND1/ENSG00000080822.12 0.888 LSM7/ENSG00000130332.9 0.888 GTF2F2/ENSG00000188342.7 0.887 SRPK1/ENSG00000096063.10 0.887 PDCD5/ENSG00000105185.6 0.882 RNPS1/ENSG00000205937.7 0.88 RSL24D1/ENSG00000137876.5 0.877 MRPS18A/ENSG00000096080.7 0.876 ANXA7/ENSG00000138279.10 0.876 DNAJA1/ENSG00000086061.11 0.875 UTP11L/ENSG00000183520.7 0.874 NUP54/ENSG00000138750.10 0.872 VPS26A/ENSG00000122958.10 0.872 EML4/ENSG00000143924.14 0.868 TPM4/ENSG00000167460.10 0.866 GLUL/ENSG00000135821.11 0.863 HNRNPA3/ENSG00000170144.14 0.861 ORC3/ENSG00000135336.8 0.861 HSPA4/ENSG00000170606.9 0.859 CPSF3/ENSG00000119203.9 0.857 PCID2/ENSG00000126226.16 0.857 BRIX1/ENSG00000113460.8 0.853 DHX9/ENSG00000135829.12 0.85 TMEM126B/ENSG00000171204.8 0.849 PSMD6/ENSG00000163636.6 0.848 PSMD7/ENSG00000103035.6 0.846 ALDH7A1/ENSG00000164904.11 0.844 PPIG/ENSG00000138398.11 0.844 PMPCB/ENSG00000105819.9 0.843 MDH2/ENSG00000146701.6 0.842 PRDX3/ENSG00000165672.5 0.84 PSMB7/ENSG00000136930.8 0.84 MRPS9/ENSG00000135972.4 0.838 POLR2G/ENSG00000168002.7 0.837 MEST/ENSG00000106484.9 0.836 TTC1/ENSG00000113312.6 0.835 ZNF814/ENSG00000204514.5 0.833 RQCD1/ENSG00000144580.9 0.832 PABPC4/ENSG00000090621.9 0.831 GTPBP4/ENSG00000107937.14 0.83 SRSF3/ENSG00000112081.11 0.83 SNRNP40/ENSG00000060688.8 0.826 RPL26L1/ENSG00000037241.3 0.824 C22ORF28/ENSG00000100220.7 0.823 PBDC1/ENSG00000102390.6 0.817 EIF4B/ENSG00000063046.13 0.817 MAPK1IP1L/ENSG00000168175.9 0.816 DNMT1/ENSG00000130816.10 0.815 RP11-466H18.1/ENSG00000244398.1 0.814 WRB/ENSG00000182093.9 0.814 IGF2BP3/ENSG00000136231.9 0.813 KPNB1/ENSG00000108424.5 0.813 PIH1D1/ENSG00000104872.6 0.811 NSL1/ENSG00000117697.10 0.809 EIF2S2/ENSG00000125977.6 0.809 CCDC90B/ENSG00000137500.5 0.805 CEP95/ENSG00000258890.2 0.804 FRG1/ENSG00000109536.7 0.803 PSMC1/ENSG00000100764.9 0.802 FABP5/ENSG00000164687.6 0.801 PWP1/ENSG00000136045.7 0.801 RCHY1/ENSG00000163743.9 0.799 GNAI3/ENSG00000065135.7 0.798 MRPS27/ENSG00000113048.12 0.797 DDOST/ENSG00000244038.4 0.796 EIF3A/ENSG00000107581.7 0.794 LYRM4/ENSG00000214113.5 0.793 RUVBL1/ENSG00000175792.7 0.793 SDAD1/ENSG00000198301.7 0.79 PQBP1/ENSG00000102103.11 0.789 FXR1/ENSG00000114416.12 0.785 PSMD10/ENSG00000101843.14 0.784 DPM1/ENSG00000000419.8 0.783 MAGOHB/ENSG00000111196.5 0.782 C16ORF80/ENSG00000070761.3 0.78 PDCL3/ENSG00000115539.9 0.78 NAP1L4/ENSG00000205531.8 0.78 SNX2/ENSG00000205302.2 0.778 SEPT2/ENSG00000168385.13 0.778 AP1M2/ENSG00000129354.7 0.776 YTHDF2/ENSG00000198492.10 0.776 TIMM17A/ENSG00000134375.6 0.775 GPATCH4/ENSG00000160818.12 0.775 MARS/ENSG00000166986.8 0.772 MPHOSPH6/ENSG00000135698.5 0.772 PPP1R7/ENSG00000115685.10 0.771 NOP16/ENSG00000048162.15 0.771 PTRHD1/ENSG00000184924.4 0.769 CNDP2/ENSG00000133313.10 0.766 CASP3/ENSG00000164305.13 0.766 PGM3/ENSG00000013375.10 0.766 C17ORF76-AS1/ENSG00000175061.12 0.764 TATDN1/ENSG00000147687.11 0.763 SRSF1/ENSG00000136450.7 0.76 SSU72/ENSG00000160075.10 0.759 PNN/ENSG00000100941.4 0.758 DDX39B/ENSG00000198563.9 0.755 SUB1/ENSG00000113387.7 0.754 MRPL16/ENSG00000166902.4 0.754 ORC4/ENSG00000115947.8 0.753 ZNHIT3/ENSG00000108278.7 0.753 MTAP/ENSG00000099810.13 0.75 CYB5B/ENSG00000103018.12 0.749 EIF1AY/ENSG00000198692.5 0.749 FLAD1/ENSG00000160688.14 0.748 MRPS15/ENSG00000116898.7 0.747 TOP2B/ENSG00000077097.9 0.746 ALG8/ENSG00000159063.8 0.744 BEX4/ENSG00000102409.9 0.744 BTF3L4/ENSG00000134717.13 0.743 VKORC1/ENSG00000167397.10 0.743 STARD3NL/ENSG00000010270.9 0.742 MRPL22/ENSG00000082515.12 0.742 IST1/ENSG00000182149.14 0.741 NUP88/ENSG00000108559.7 0.741 PLRG1/ENSG00000171566.7 0.74 PRMT5/ENSG00000100462.11 0.74 DDX1/ENSG00000079785.10 0.739 CHURC1/ENSG00000258289.2 0.739 THUMPD1/ENSG00000066654.8 0.734 NUDCD2/ENSG00000170584.5 0.733 AGTRAP/ENSG00000177674.11 0.731 COPS4/ENSG00000138663.4 0.729 SFT2D1/ENSG00000198818.5 0.727 ACTR10/ENSG00000131966.8 0.727 ZC3H15/ENSG00000065548.13 0.725 TMEM14C/ENSG00000111843.9 0.724 REXO2/ENSG00000076043.5 0.723 RSU1/ENSG00000148484.13 0.722 AP2M1/ENSG00000161203.9 0.722 MOB4/ENSG00000115540.10 0.722 MAT2A/ENSG00000168906.8 0.721 RFC1/ENSG00000035928.10 0.721 CHORDC1/ENSG00000110172.7 0.72 RNF5/ENSG00000204308.6 0.72 KIAA1191/ENSG00000122203.10 0.719 NGDN/ENSG00000129460.11 0.718 C12ORF45/ENSG00000151131.5 0.716 EEF1D/ENSG00000104529.13 0.715 COMMD1/ENSG00000173163.6 0.715 METAP1/ENSG00000164024.7 0.715 C12ORF10/ENSG00000139637.9 0.715 EIF2S3/ENSG00000130741.5 0.714 PFN2/ENSG00000070087.9 0.712 ABCE1/ENSG00000164163.6 0.712 ZNF195/ENSG00000005801.12 0.711 MRPS6/ENSG00000243927.1 0.71 PRDX4/ENSG00000123131.8 0.71 DPY30/ENSG00000162961.9 0.71 PTPN2/ENSG00000175354.13 0.709 GMFB/ENSG00000197045.8 0.709 WARS/ENSG00000140105.12 0.708 RP5-1085F17.3/ENSG00000260257.1 0.708 MKI67IP/ENSG00000155438.7 0.708 EEF2/ENSG00000167658.11 0.708 DARS/ENSG00000115866.6 0.707 SPAG7/ENSG00000091640.3 0.704 SSRP1/ENSG00000149136.3 0.704 MRPL55/ENSG00000162910.14 0.702 DROSHA/ENSG00000113360.12 0.702 CRBN/ENSG00000113851.9 0.702 STRN3/ENSG00000196792.7 0.701 GLOD4/ENSG00000167699.9 0.698 RP11-632C17__A.1/ENSG00000230202.1 0.697 PRMT1/ENSG00000126457.16 0.697 WDR43/ENSG00000163811.7 0.697 MRPS24/ENSG00000062582.9 0.696 SYNC/ENSG00000162520.10 0.695 STX8/ENSG00000170310.8 0.694 WBSCR22/ENSG00000071462.7 0.693 RBBP7/ENSG00000102054.13 0.692 ERAL1/ENSG00000132591.7 0.692 GSKIP/ENSG00000100744.10 0.69 YWHAB/ENSG00000166913.8 0.69 COA4/ENSG00000181924.6 0.689 CAPZB/ENSG00000077549.13 0.688 PPID/ENSG00000171497.4 0.687 PHB2/ENSG00000215021.3 0.686 MTHFD1/ENSG00000100714.10 0.684 SMYD3/ENSG00000185420.14 0.682 MRPS18C/ENSG00000163319.6 0.682 COPS2/ENSG00000166200.10 0.682 AARSD1/ENSG00000266967.2 0.681 METTL5/ENSG00000138382.9 0.679 TPR/ENSG00000047410.8 0.679 PIN4/ENSG00000102309.8 0.679 MRPS22/ENSG00000175110.7 0.678 GEMIN7/ENSG00000142252.6 0.678 STRA13/ENSG00000169689.10 0.677 HMGCS1/ENSG00000112972.10 0.677 PAK1IP1/ENSG00000111845.4 0.676 EIF3G/ENSG00000130811.6 0.676 IMMP1L/ENSG00000148950.5 0.674 MRPL14/ENSG00000180992.5 0.673 TBPL1/ENSG00000028839.4 0.673 MRPL10/ENSG00000159111.8 0.672 MSMO1/ENSG00000052802.8 0.671 SNRPB/ENSG00000125835.13 0.67 SIVA1/ENSG00000184990.8 0.67 TROVE2/ENSG00000116747.8 0.668 HSPH1/ENSG00000120694.15 0.668 POLD2/ENSG00000106628.6 0.667 NT5DC2/ENSG00000168268.6 0.666 TMEM256/ENSG00000205544.3 0.666 VDAC3/ENSG00000078668.9 0.666 WFDC2/ENSG00000101443.13 0.664 HDDC2/ENSG00000111906.12 0.662 CS/ENSG00000062485.14 0.661 AMD1/ENSG00000123505.10 0.658 PCCB/ENSG00000114054.9 0.657 WTAP/ENSG00000146457.10 0.656 NDUFAF4/ENSG00000123545.5 0.655 MRPL48/ENSG00000175581.9 0.654 NOL8/ENSG00000198000.7 0.654 DNM1L/ENSG00000087470.13 0.654 C7ORF73/ENSG00000243317.3 0.653 PTS/ENSG00000150787.3 0.653 CHP1/ENSG00000187446.7 0.652 SLC38A2/ENSG00000134294.9 0.651 LRPPRC/ENSG00000138095.14 0.649 ZNF146/ENSG00000167635.7 0.648 XRN2/ENSG00000088930.6 0.647 ACAA2/ENSG00000167315.13 0.647 MAPK6/ENSG00000069956.7 0.647 ABCF1/ENSG00000204574.8 0.646 NAA38/ENSG00000128534.3 0.645 ZFAS1/ENSG00000177410.8 0.643 ACADM/ENSG00000117054.9 0.643 MRPS35/ENSG00000061794.8 0.642 MARCH7/ENSG00000136536.9 0.642 PSMB3/ENSG00000108294.4 0.642 ST6GALNAC2/ENSG00000070731.5 0.641 NOB1/ENSG00000141101.8 0.641 SNRNP27/ENSG00000124380.6 0.64 CDC23/ENSG00000094880.6 0.64 TMEM97/ENSG00000109084.9 0.639 TPGS2/ENSG00000134779.10 0.637 SKIV2L2/ENSG00000039123.11 0.637 FAM76A/ENSG00000009780.11 0.636 MTX2/ENSG00000128654.9 0.635 KHDRBS1/ENSG00000121774.12 0.635 POLR1D/ENSG00000186184.11 0.635 TUBG1/ENSG00000131462.3 0.634 KIAA0020/ENSG00000080608.9 0.632 POLR2H/ENSG00000163882.5 0.631 FAM96B/ENSG00000166595.7 0.63 MRPS16/ENSG00000182180.9 0.63 WDR75/ENSG00000115368.5 0.629 MYSM1/ENSG00000162601.5 0.627 MED6/ENSG00000133997.7 0.626 NAA50/ENSG00000121579.7 0.625 EIF5B/ENSG00000158417.5 0.625 DCTPP1/ENSG00000179958.4 0.623 LTA4H/ENSG00000111144.5 0.623 NTPCR/ENSG00000135778.6 0.622 HN1L/ENSG00000206053.8 0.622 C1ORF123/ENSG00000162384.9 0.621 RPP14/ENSG00000163684.6 0.62 MED28/ENSG00000118579.6 0.62 FAM133B/ENSG00000234545.3 0.619 FARSB/ENSG00000116120.8 0.617 CDK4/ENSG00000135446.12 0.617 CTB-63M22.1/ENSG00000229119.3 0.616 SSR3/ENSG00000114850.2 0.614 HMGN3/ENSG00000118418.10 0.613 TTLL5/ENSG00000119685.14 0.611 CCBL2/ENSG00000137944.12 0.611 MRPL19/ENSG00000115364.9 0.611 NUP93/ENSG00000102900.7 0.608 MRPS28/ENSG00000147586.4 0.607 OARD1/ENSG00000124596.12 0.606 EMC2/ENSG00000104412.3 0.606 CEBPZ/ENSG00000115816.9 0.604 MRPS31/ENSG00000102738.6 0.603 DDX10/ENSG00000178105.5 0.601 MRPS10/ENSG00000048544.5 0.601 LEO1/ENSG00000166477.8 0.6 AC007347.1/ENSG00000214696.3 0.6 ACLY/ENSG00000131473.12 0.599 PRPF38A/ENSG00000134748.11 0.598 WDR1/ENSG00000071127.12 0.597 DNAJC2/ENSG00000105821.10 0.596 CDC26/ENSG00000176386.4 0.594 RPS26/ENSG00000197728.5 0.593 TWISTNB/ENSG00000105849.5 0.593 UMPS/ENSG00000114491.9 0.592 SLC38A1/ENSG00000111371.11 0.591 TMEM216/ENSG00000187049.5 0.591 BLOC1S2/ENSG00000196072.7 0.59 SHMT2/ENSG00000182199.6 0.589 FAM45A/ENSG00000119979.11 0.587 C17ORF75/ENSG00000108666.5 0.586 MRS2/ENSG00000124532.10 0.585 FARSA/ENSG00000179115.6 0.585 ASNS/ENSG00000070669.12 0.583 KIAA1033/ENSG00000136051.9 0.583 HMGCR/ENSG00000113161.11 0.583 HDAC3/ENSG00000171720.4 0.583 PRR13/ENSG00000205352.6 0.581 TXLNG2P/ENSG00000131002.7 0.579 F11R/ENSG00000158769.12 0.577 EIF2B3/ENSG00000070785.12 0.577 RNF4/ENSG00000063978.11 0.576 MRPS17/ENSG00000239789.1 0.576 PSMD12/ENSG00000197170.5 0.576 ANAPC10/ENSG00000164162.8 0.574 TRMT11/ENSG00000066651.12 0.574 HMBS/ENSG00000256269.2 0.574 TRMT10C/ENSG00000174173.6 0.573 TSNAX/ENSG00000116918.9 0.572 TIA1/ENSG00000116001.11 0.572 ARIH2/ENSG00000177479.15 0.571 TMA16/ENSG00000198498.5 0.569 EBNA1BP2/ENSG00000117395.6 0.569 CCNB1IP1/ENSG00000100814.13 0.569 MDM2/ENSG00000135679.17 0.569 USP10/ENSG00000103194.11 0.568 POP5/ENSG00000167272.6 0.567 RBM7/ENSG00000076053.6 0.566 MRPL18/ENSG00000112110.5 0.566 KIF2A/ENSG00000068796.12 0.566 DTWD1/ENSG00000104047.10 0.563 ZMPSTE24/ENSG00000084073.4 0.563 STAU2/ENSG00000040341.13 0.562 CTNNA1/ENSG00000044115.15 0.561 PMS1/ENSG00000064933.12 0.559 CTPS1/ENSG00000171793.9 0.559 DENR/ENSG00000139726.6 0.558 EFTUD2/ENSG00000108883.8 0.557 RARS2/ENSG00000146282.13 0.556 RPE/ENSG00000197713.10 0.556 DFFA/ENSG00000160049.7 0.555 EMG1/ENSG00000126749.8 0.554 SCAMP1/ENSG00000085365.13 0.554 MRPL50/ENSG00000136897.6 0.554 FBL/ENSG00000105202.3 0.552 CD24P4/ENSG00000185275.6 0.551 KRR1/ENSG00000111615.8 0.55 MITD1/ENSG00000158411.6 0.548 ZFAND1/ENSG00000104231.6 0.547 FTSJ2/ENSG00000122687.13 0.545 RNF181/ENSG00000168894.5 0.544 DDX18/ENSG00000088205.8 0.544 FUNDC2/ENSG00000165775.13 0.543 MAGOH/ENSG00000162385.6 0.542 TPP2/ENSG00000134900.7 0.54 CMC2/ENSG00000103121.4 0.539 IFT52/ENSG00000101052.8 0.538 CSTF1/ENSG00000101138.7 0.538 NIP7/ENSG00000132603.9 0.537 FASTKD2/ENSG00000118246.9 0.536 PPAPDC1B/ENSG00000147535.12 0.535 LTV1/ENSG00000135521.8 0.534 ATP6V1B2/ENSG00000147416.6 0.533 C11ORF1/ENSG00000137720.3 0.532 AC004696.2/ENSG00000166770.6 0.531 PPWD1/ENSG00000113593.7 0.531 PTP4A2/ENSG00000184007.13 0.531 USP39/ENSG00000168883.15 0.53 TRAPPC4/ENSG00000196655.5 0.529 NDUFA8/ENSG00000119421.5 0.525 METTL17/ENSG00000165792.13 0.524 TSFM/ENSG00000123297.12 0.523 BDH2/ENSG00000164039.10 0.523 SMU1/ENSG00000122692.7 0.523 MRPL9/ENSG00000143436.6 0.522 CTB-12A17.3/ENSG00000269292.1 0.521 TMEM69/ENSG00000159596.6 0.521 UBAP2L/ENSG00000143569.14 0.519 RRM1/ENSG00000167325.10 0.519 MRPL44/ENSG00000135900.3 0.519 DAXX/ENSG00000204209.6 0.518 MRPL32/ENSG00000106591.3 0.518 RN7SL1/ENSG00000258486.1 0.518 PPIL4/ENSG00000131013.3 0.517 ZNF644/ENSG00000122482.16 0.517 FAR1/ENSG00000197601.8 0.515 IMMP2L/ENSG00000184903.5 0.515 KARS/ENSG00000065427.10 0.515 PARP2/ENSG00000129484.9 0.513 SMARCC1/ENSG00000173473.6 0.513 TRNAU1AP/ENSG00000180098.5 0.512 MRPS21/ENSG00000187145.10 0.51 FOPNL/ENSG00000133393.8 0.509 C1ORF174/ENSG00000198912.6 0.509 ATP5SL/ENSG00000105341.14 0.508 C14ORF1/ENSG00000133935.6 0.508 MRPL1/ENSG00000169288.13 0.508 OTUB1/ENSG00000167770.7 0.507 HNRNPAB/ENSG00000197451.6 0.506 EXOSC3/ENSG00000107371.7 0.506 YARS/ENSG00000134684.6 0.506 SLC30A9/ENSG00000014824.8 0.505 DDX21/ENSG00000165732.8 0.505 NUDT21/ENSG00000167005.9 0.504 APOO/ENSG00000184831.9 0.504 NFYB/ENSG00000120837.3 0.5 TBRG4/ENSG00000136270.9 0.5 FADS1/ENSG00000149485.11 0.499 RSRC2/ENSG00000111011.13 0.498 MAK16/ENSG00000198042.6 0.496 AAAS/ENSG00000094914.8 0.496 SAAL1/ENSG00000166788.5 0.495 SMARCA4/ENSG00000127616.12 0.495 PARK7/ENSG00000116288.8 0.494 STAU1/ENSG00000124214.15 0.494 PGRMC1/ENSG00000101856.8 0.493 "GJA9,MYCBP/ENSG00000214114.4" 0.493 COPB2/ENSG00000184432.4 0.492 TIMM21/ENSG00000075336.7 0.491 RHOA/ENSG00000067560.6 0.49 AZI2/ENSG00000163512.9 0.489 RP11-3P17.5/ENSG00000269888.1 0.489 AC010761.8/ENSG00000264577.1 0.489 C11ORF31/ENSG00000211450.5 0.489 TXNL1/ENSG00000091164.8 0.489 DCTN6/ENSG00000104671.3 0.487 SNAPC5/ENSG00000174446.7 0.487 ACTR1A/ENSG00000138107.7 0.487 PAM16/ENSG00000217930.3 0.486 U2AF1/ENSG00000160201.7 0.485 TFB1M/ENSG00000029639.6 0.484 TXNRD1/ENSG00000198431.11 0.483 ACP1/ENSG00000143727.11 0.483 GHITM/ENSG00000165678.15 0.483 ZCCHC7/ENSG00000147905.13 0.482 FAM49B/ENSG00000153310.14 0.482 PEX19/ENSG00000162735.13 0.481 EXOSC9/ENSG00000123737.8 0.481 MTHFD2/ENSG00000065911.7 0.481 C1ORF52/ENSG00000162642.9 0.48 CEP57/ENSG00000166037.6 0.48 BLVRA/ENSG00000106605.6 0.48 MCRS1/ENSG00000187778.9 0.479 RPA3/ENSG00000106399.7 0.478 TFAM/ENSG00000108064.6 0.477 ACTL6A/ENSG00000136518.12 0.476 YWHAH/ENSG00000128245.10 0.476 ELP5/ENSG00000170291.9 0.476 RRP15/ENSG00000067533.5 0.475 PTRH2/ENSG00000141378.13 0.474 RNMT/ENSG00000101654.13 0.474 TCTEX1D2/ENSG00000213123.5 0.474 ITGB3BP/ENSG00000142856.12 0.473 FASTKD1/ENSG00000138399.13 0.473 TM2D2/ENSG00000169490.12 0.472 PSMG2/ENSG00000128789.15 0.472 C1GALT1/ENSG00000106392.5 0.471 CACUL1/ENSG00000151893.10 0.471 RPF2/ENSG00000197498.7 0.471 FAM192A/ENSG00000172775.12 0.47 LAP3/ENSG00000002549.7 0.47 FBXO22/ENSG00000167196.9 0.47 ARPP19/ENSG00000128989.6 0.469 MRPS33/ENSG00000090263.11 0.469 GOT1/ENSG00000120053.9 0.469 VPS72/ENSG00000163159.7 0.467 WAPAL/ENSG00000062650.13 0.467 TMEM18/ENSG00000151353.10 0.467 NUP205/ENSG00000155561.9 0.467 SNAP23/ENSG00000092531.5 0.466 POLE3/ENSG00000148229.8 0.466 MRPL43/ENSG00000055950.12 0.465 NUP37/ENSG00000075188.4 0.464 ABT1/ENSG00000146109.3 0.463 QTRTD1/ENSG00000151576.6 0.462 TXLNA/ENSG00000084652.11 0.462 MMS19/ENSG00000155229.16 0.461 PRPF4B/ENSG00000112739.12 0.461 TAF12/ENSG00000120656.7 0.461 STAG2/ENSG00000101972.14 0.46 CISD2/ENSG00000145354.5 0.46 ORC5/ENSG00000164815.6 0.46 HADH/ENSG00000138796.11 0.46 TMEM87A/ENSG00000103978.11 0.459 CTNNBL1/ENSG00000132792.14 0.458 TCEA1/ENSG00000187735.8 0.458 ACTR6/ENSG00000075089.5 0.458 SS18/ENSG00000141380.9 0.458 YEATS4/ENSG00000127337.2 0.458 ELOVL6/ENSG00000170522.5 0.458 RAE1/ENSG00000101146.8 0.457 PPM1G/ENSG00000115241.9 0.457 ZNF721/ENSG00000182903.11 0.457 GRPEL1/ENSG00000109519.8 0.456 MFAP1/ENSG00000140259.6 0.455 CLDN7/ENSG00000181885.14 0.455 PITPNB/ENSG00000180957.13 0.454 C5ORF22/ENSG00000082213.13 0.454 RP11-603J24.17/ENSG00000257553.1 0.452 CENPV/ENSG00000166582.5 0.452 PFDN4/ENSG00000101132.5 0.452 GNB1/ENSG00000078369.12 0.451 TMEM254/ENSG00000133678.9 0.451 POLR2D/ENSG00000144231.6 0.45 DPH5/ENSG00000117543.15 0.45 GTF2I/ENSG00000077809.8 0.447 KIAA1551/ENSG00000174718.7 0.447 GPN3/ENSG00000111231.3 0.446 SEC23B/ENSG00000101310.10 0.446 C21ORF33/ENSG00000160221.12 0.445 NSFL1C/ENSG00000088833.12 0.445 SLC31A1/ENSG00000136868.9 0.444 TTC9C/ENSG00000162222.9 0.441 GEMIN2/ENSG00000092208.12 0.44 RCN2/ENSG00000117906.9 0.44 PAIP1/ENSG00000172239.9 0.439 MRPL17/ENSG00000158042.8 0.438 COQ5/ENSG00000110871.10 0.438 PIGU/ENSG00000101464.6 0.438 KDM1A/ENSG00000004487.11 0.437 NDUFA6/ENSG00000184983.5 0.437 SNHG3/ENSG00000242125.1 0.436 INTS8/ENSG00000164941.9 0.436 MRP63/ENSG00000173141.4 0.436 SMARCA5/ENSG00000153147.5 0.435 NIF3L1/ENSG00000196290.10 0.434 TMEM11/ENSG00000178307.5 0.434 SNRNP25/ENSG00000161981.6 0.434 ZC3H14/ENSG00000100722.14 0.434 PSMC6/ENSG00000100519.6 0.434 SPTLC1/ENSG00000090054.9 0.433 GTF2H1/ENSG00000110768.6 0.433 GSPT1/ENSG00000103342.8 0.432 MLH1/ENSG00000076242.10 0.432 SLC20A1/ENSG00000144136.6 0.431 ZCCHC10/ENSG00000155329.7 0.429 HSD17B10/ENSG00000072506.8 0.429 GOT2/ENSG00000125166.8 0.428 FUBP1/ENSG00000162613.12 0.427 ILF3/ENSG00000129351.13 0.427 EXOSC2/ENSG00000130713.11 0.427 LRRC40/ENSG00000066557.5 0.427 RPN1/ENSG00000163902.7 0.426 CORO1C/ENSG00000110880.6 0.424 PRKCI/ENSG00000163558.8 0.423 PFDN2/ENSG00000143256.4 0.423 IFI27L2/ENSG00000119632.3 0.423 RPF1/ENSG00000117133.6 0.423 KAT7/ENSG00000136504.7 0.422 POLR2E/ENSG00000099817.7 0.421 THAP9-AS1/ENSG00000251022.1 0.42 TKT/ENSG00000163931.11 0.42 CNIH/ENSG00000100528.7 0.419 POLR3E/ENSG00000058600.11 0.418 PIGL/ENSG00000108474.10 0.416 PPP2R1B/ENSG00000137713.11 0.416 SAMM50/ENSG00000100347.10 0.416 RP11-770J1.5/ENSG00000254873.1 0.416 H3F3AP4/ENSG00000235655.2 0.416 UBA1/ENSG00000130985.12 0.416 ALDH3A2/ENSG00000072210.14 0.416 UCHL5/ENSG00000116750.8 0.415 AIMP2/ENSG00000106305.5 0.414 NUP85/ENSG00000125450.6 0.414 DUSP11/ENSG00000144048.6 0.414 UBE2D3/ENSG00000109332.15 0.413 HNRNPM/ENSG00000099783.7 0.412 C11ORF49/ENSG00000149179.8 0.412 AQR/ENSG00000021776.6 0.411 NSMCE1/ENSG00000169189.12 0.41 CBX1/ENSG00000108468.10 0.41 PRPF39/ENSG00000185246.13 0.409 UBA2/ENSG00000126261.7 0.407 EIF3F/ENSG00000175390.8 0.407 INO80C/ENSG00000153391.11 0.407 PARN/ENSG00000140694.12 0.406 FAM118B/ENSG00000197798.4 0.406 IWS1/ENSG00000163166.9 0.406 MRPL36/ENSG00000171421.8 0.404 AC006011.4/ENSG00000244563.1 0.404 PAWR/ENSG00000177425.6 0.404 VCL/ENSG00000035403.12 0.402 RPAP3/ENSG00000005175.5 0.402 PSMG3/ENSG00000157778.4 0.402 CWC15/ENSG00000150316.7 0.402 ALKBH5/ENSG00000091542.8 0.401 RIOK2/ENSG00000058729.6 0.4 PSMC2/ENSG00000161057.6 0.399 AC009120.6/ENSG00000259972.1 0.398 POLR2B/ENSG00000047315.10 0.396 ZCCHC9/ENSG00000131732.7 0.396 NAMPT/ENSG00000105835.7 0.395 MOSPD1/ENSG00000101928.8 0.394 BCAP31/ENSG00000185825.10 0.393 VMA21/ENSG00000160131.9 0.393 OGFOD1/ENSG00000087263.12 0.393 ADK/ENSG00000156110.9 0.393 SACM1L/ENSG00000211456.6 0.389 SMEK1/ENSG00000100796.13 0.389 MTMR2/ENSG00000087053.14 0.389 AARS/ENSG00000090861.11 0.388 KIAA0391/ENSG00000100890.11 0.388 HSPA14/ENSG00000187522.9 0.388 PISD/ENSG00000241878.5 0.387 THAP4/ENSG00000176946.7 0.387 SEH1L/ENSG00000085415.11 0.387 TSTA3/ENSG00000104522.11 0.385 TAF15/ENSG00000172660.7 0.384 PPAT/ENSG00000128059.4 0.383 MYO19/ENSG00000141140.12 0.382 PHGDH/ENSG00000092621.7 0.382 SNRPG/ENSG00000143977.9 0.381 UBE2G2/ENSG00000184787.14 0.379 COMMD2/ENSG00000114744.4 0.379 CELF1/ENSG00000149187.13 0.377 TMEM177/ENSG00000144120.8 0.377 KRAS/ENSG00000133703.7 0.376 TAF1B/ENSG00000115750.11 0.374 GORASP2/ENSG00000115806.8 0.373 UCK2/ENSG00000143179.7 0.372 TIMP1/ENSG00000102265.7 0.372 SIKE1/ENSG00000052723.7 0.37 SEPT7/ENSG00000122545.13 0.37 TBCD/ENSG00000141556.15 0.369 MTERFD1/ENSG00000156469.4 0.369 RP11-111M22.3/ENSG00000255135.2 0.369 S100A13/ENSG00000189171.8 0.368 PARL/ENSG00000175193.8 0.368 NUP35/ENSG00000163002.8 0.366 YME1L1/ENSG00000136758.14 0.366 MRE11A/ENSG00000020922.7 0.365 MTRR/ENSG00000124275.10 0.364 CRK/ENSG00000167193.7 0.364 UBLCP1/ENSG00000164332.6 0.364 MRPL35/ENSG00000132313.10 0.364 GEMIN6/ENSG00000152147.5 0.363 DHPS/ENSG00000095059.11 0.363 TIMM8B/ENSG00000150779.7 0.363 CEP70/ENSG00000114107.4 0.362 ATP1B3/ENSG00000069849.6 0.361 ABCB7/ENSG00000131269.11 0.361 PSME3/ENSG00000131467.6 0.361 MRPL46/ENSG00000259494.1 0.359 ABHD4/ENSG00000100439.6 0.359 TRIM28/ENSG00000130726.7 0.359 GTF3C2/ENSG00000115207.9 0.358 GTF2H3/ENSG00000111358.9 0.356 SLC25A17/ENSG00000100372.10 0.356 GOLGA7/ENSG00000147533.12 0.356 OAT/ENSG00000065154.7 0.356 DCUN1D4/ENSG00000109184.10 0.355 ASUN/ENSG00000064102.10 0.355 MRPL30/ENSG00000185414.14 0.355 RP4-564F22.2/ENSG00000196756.6 0.354 MRRF/ENSG00000148187.12 0.354 ATG10/ENSG00000152348.11 0.354 TMEM126A/ENSG00000171202.2 0.352 BCS1L/ENSG00000074582.8 0.351 STXBP3/ENSG00000116266.6 0.351 CDK5RAP1/ENSG00000101391.15 0.35 NMRAL1/ENSG00000153406.9 0.349 DPAGT1/ENSG00000172269.12 0.349 NUDCD1/ENSG00000120526.6 0.349 FTSJ1/ENSG00000068438.10 0.349 SRSF4/ENSG00000116350.11 0.348 G6PC3/ENSG00000141349.4 0.347 IPO7/ENSG00000205339.5 0.347 EPRS/ENSG00000136628.12 0.347 MOB1A/ENSG00000114978.12 0.346 KXD1/ENSG00000105700.6 0.345 RPAP1/ENSG00000103932.7 0.345 CHCHD7/ENSG00000170791.13 0.343 ZMYM1/ENSG00000197056.5 0.342 TBCE/ENSG00000116957.8 0.342 MRPL11/ENSG00000174547.9 0.342 TYW3/ENSG00000162623.10 0.341 PRPF38B/ENSG00000134186.7 0.34 WIBG/ENSG00000170473.12 0.339 PUF60/ENSG00000179950.9 0.338 YES1/ENSG00000176105.9 0.338 CUL2/ENSG00000108094.10 0.337 TIMMDC1/ENSG00000113845.5 0.337 ETFA/ENSG00000140374.11 0.337 ARL1/ENSG00000120805.9 0.337 CBWD1/ENSG00000172785.14 0.337 ERCC8/ENSG00000049167.9 0.337 TAF11/ENSG00000064995.12 0.336 MAT2B/ENSG00000038274.11 0.336 MFF/ENSG00000168958.15 0.336 UBR5/ENSG00000104517.8 0.335 IARS2/ENSG00000067704.8 0.335 FGFR1OP/ENSG00000213066.6 0.335 SLC11A2/ENSG00000110911.10 0.334 C12ORF5/ENSG00000078237.4 0.333 POLB/ENSG00000070501.7 0.333 WDR54/ENSG00000005448.12 0.333 RPP30/ENSG00000148688.9 0.332 DDX6/ENSG00000110367.6 0.33 NOL10/ENSG00000115761.11 0.33 NRBF2/ENSG00000148572.10 0.33 RBM18/ENSG00000119446.9 0.329 DCAF13/ENSG00000164934.9 0.328 CYP20A1/ENSG00000119004.10 0.327 KPNA6/ENSG00000025800.9 0.327 C2ORF43/ENSG00000118961.10 0.326 PAAF1/ENSG00000175575.8 0.326 TMEM41B/ENSG00000166471.6 0.325 KNOP1/ENSG00000103550.9 0.325 SEPHS1/ENSG00000086475.10 0.325 UBL7/ENSG00000138629.11 0.323 TIMM22/ENSG00000177370.3 0.321 WDR3/ENSG00000065183.10 0.321 GOLPH3L/ENSG00000143457.6 0.32 IQCB1/ENSG00000173226.12 0.319 RTFDC1/ENSG00000022277.8 0.319 SOX4/ENSG00000124766.4 0.319 NUP50/ENSG00000093000.13 0.318 "RPL17,RPL17-C18ORF32/ENSG00000215472.4" 0.317 SDR39U1/ENSG00000100445.12 0.316 YY1/ENSG00000100811.5 0.316 CAAP1/ENSG00000120159.7 0.315 DDX50/ENSG00000107625.8 0.314 C6ORF203/ENSG00000130349.5 0.314 RNF168/ENSG00000163961.4 0.314 PDRG1/ENSG00000088356.4 0.314 GNPAT/ENSG00000116906.7 0.313 FTO/ENSG00000140718.14 0.313 KIAA1586/ENSG00000168116.9 0.313 GMPR2/ENSG00000100938.13 0.313 C12ORF29/ENSG00000133641.13 0.313 TIMM50/ENSG00000105197.5 0.312 SLC25A13/ENSG00000004864.9 0.312 NEK3/ENSG00000136098.11 0.312 TMEM258/ENSG00000134825.8 0.311 NUDT15/ENSG00000136159.3 0.31 WDR77/ENSG00000116455.9 0.309 ZNRD1/ENSG00000066379.10 0.309 ADD3/ENSG00000148700.9 0.308 GTPBP8/ENSG00000163607.10 0.308 TSR1/ENSG00000167721.5 0.308 ZNF232/ENSG00000167840.9 0.308 AP3M1/ENSG00000185009.8 0.307 CUL4A/ENSG00000139842.10 0.307 LSM3/ENSG00000170860.3 0.307 GSS/ENSG00000100983.5 0.306 PPP1CC/ENSG00000186298.7 0.306 MKLN1/ENSG00000128585.13 0.305 DNAJB6/ENSG00000105993.10 0.305 NTMT1/ENSG00000148335.10 0.305 GOSR2/ENSG00000108433.10 0.305 PAK1/ENSG00000149269.5 0.304 RABEPK/ENSG00000136933.12 0.303 MOB4/ENSG00000270757.1 0.303 NUDCD3/ENSG00000015676.12 0.303 ACY1/ENSG00000243989.3 0.303 COMMD4/ENSG00000140365.11 0.303 EXOSC1/ENSG00000171311.8 0.302 CMSS1/ENSG00000184220.6 0.301 TMEM251/ENSG00000153485.5 0.301 C1ORF109/ENSG00000116922.9 0.301 XPNPEP1/ENSG00000108039.13 0.301 TIMM17B/ENSG00000126768.7 0.3 RAC1/ENSG00000136238.13 0.3 MRPS12/ENSG00000128626.7 0.3 PPIH/ENSG00000171960.6 0.299 XPO5/ENSG00000124571.13 0.299 CLP1/ENSG00000172409.5 0.299 TTC4/ENSG00000243725.2 0.298 HOMER1/ENSG00000152413.10 0.298 USP46/ENSG00000109189.7 0.297 SLC25A3/ENSG00000075415.8 0.297 RNASEH1/ENSG00000171865.5 0.297 MLLT11/ENSG00000213190.2 0.294 ALG6/ENSG00000088035.11 0.293 ASH2L/ENSG00000129691.11 0.293 MRPL37/ENSG00000116221.11 0.293 SMIM15/ENSG00000188725.3 0.293 UBE4B/ENSG00000130939.14 0.293 LARP1/ENSG00000155506.12 0.292 NOC3L/ENSG00000173145.7 0.291 RPP40/ENSG00000124787.9 0.29 C8ORF33/ENSG00000182307.8 0.289 TECR/ENSG00000099797.7 0.289 C17ORF49/ENSG00000258315.1 0.289 EED/ENSG00000074266.13 0.289 HDHD1/ENSG00000130021.9 0.288 NXN/ENSG00000167693.12 0.288 HIAT1/ENSG00000156875.9 0.288 FAM120AOS/ENSG00000188938.11 0.287 MLF2/ENSG00000089693.6 0.287 ASCC1/ENSG00000138303.13 0.287 CDYL/ENSG00000153046.13 0.287 ESF1/ENSG00000089048.10 0.286 DDX27/ENSG00000124228.10 0.286 RP11-139H15.1/ENSG00000225973.3 0.286 QKI/ENSG00000112531.12 0.286 LAMTOR1/ENSG00000149357.5 0.285 TNPO3/ENSG00000064419.9 0.285 MESDC2/ENSG00000117899.6 0.285 ZNF138/ENSG00000197008.5 0.285 RP11-513I15.6/ENSG00000225339.2 0.285 DBF4/ENSG00000006634.3 0.284 LRIF1/ENSG00000121931.11 0.284 MANF/ENSG00000145050.11 0.283 KATNBL1/ENSG00000134152.6 0.283 DNAJC11/ENSG00000007923.11 0.283 WDR74/ENSG00000133316.10 0.283 MYH10/ENSG00000133026.8 0.283 MRPL2/ENSG00000112651.7 0.282 STAMBP/ENSG00000124356.11 0.282 GSTZ1/ENSG00000100577.14 0.281 CWC22/ENSG00000163510.9 0.281 RPUSD4/ENSG00000165526.4 0.28 FIP1L1/ENSG00000145216.11 0.279 HAT1/ENSG00000128708.8 0.279 LSG1/ENSG00000041802.6 0.279 NDUFB10/ENSG00000140990.10 0.279 EXOSC5/ENSG00000077348.4 0.279 NPC2/ENSG00000119655.4 0.278 SMC3/ENSG00000108055.9 0.278 NRBP1/ENSG00000115216.9 0.278 MIF4GD/ENSG00000125457.9 0.277 PANK2/ENSG00000125779.16 0.277 CPSF6/ENSG00000111605.12 0.276 TOX4/ENSG00000092203.8 0.276 RPSAP58/ENSG00000205246.4 0.276 APEH/ENSG00000164062.8 0.276 CCNT2/ENSG00000082258.8 0.276 CWC27/ENSG00000153015.11 0.275 PNKD/ENSG00000127838.9 0.275 EFCAB2/ENSG00000203666.8 0.275 RPL15P3/ENSG00000212802.3 0.275 KANSL2/ENSG00000139620.8 0.274 TGIF2/ENSG00000118707.4 0.274 NMT1/ENSG00000136448.7 0.274 VPS4B/ENSG00000119541.5 0.273 WDYHV1/ENSG00000156795.2 0.273 USP48/ENSG00000090686.11 0.272 SARS2/ENSG00000104835.10 0.271 CUTC/ENSG00000119929.8 0.271 CWF19L1/ENSG00000095485.12 0.271 AIMP1/ENSG00000164022.12 0.271 POLG2/ENSG00000256525.2 0.27 BBS4/ENSG00000140463.9 0.27 CSNK2B/ENSG00000204435.9 0.27 C1QBP/ENSG00000108561.4 0.27 SEPW1/ENSG00000178980.10 0.27 GEMIN8/ENSG00000046647.9 0.27 COMMD10/ENSG00000145781.4 0.27 RABL3/ENSG00000144840.4 0.269 TRAPPC8/ENSG00000153339.9 0.269 NEDD1/ENSG00000139350.7 0.269 RP11-138C9.1/ENSG00000264558.1 0.269 APOPT1/ENSG00000256053.3 0.269 OMA1/ENSG00000162600.7 0.269 USP22/ENSG00000124422.7 0.268 USP7/ENSG00000187555.10 0.268 NOP2/ENSG00000111641.6 0.267 NREP/ENSG00000134986.9 0.266 EZR/ENSG00000092820.13 0.265 GMNN/ENSG00000112312.5 0.265 CBX5/ENSG00000094916.9 0.265 ZNF28/ENSG00000198538.6 0.264 CKS1B/ENSG00000173207.8 0.264 AK2/ENSG00000004455.12 0.263 MRPL27/ENSG00000108826.11 0.263 METTL6/ENSG00000206562.7 0.263 ZNF93/ENSG00000184635.9 0.262 UBAC1/ENSG00000130560.4 0.262 NDUFAF7/ENSG00000003509.11 0.262 NUP43/ENSG00000120253.8 0.262 GOLT1B/ENSG00000111711.5 0.261 TRIT1/ENSG00000043514.11 0.261 NDUFS2/ENSG00000158864.8 0.261 SC5D/ENSG00000109929.5 0.261 EIF3J/ENSG00000104131.8 0.261 USB1/ENSG00000103005.6 0.26 TTI2/ENSG00000129696.8 0.26 AL139819.1/ENSG00000256545.1 0.257 RNF138/ENSG00000134758.9 0.257 METTL13/ENSG00000010165.14 0.256 MED27/ENSG00000160563.8 0.256 UPRT/ENSG00000094841.9 0.256 CIRH1A/ENSG00000141076.12 0.256 AAR2/ENSG00000131043.7 0.256 MED20/ENSG00000124641.10 0.255 LMAN2L/ENSG00000114988.7 0.255 ARG2/ENSG00000081181.3 0.253 PPP6C/ENSG00000119414.7 0.253 RP11-216F19.2/ENSG00000270674.1 0.253 SLC5A6/ENSG00000138074.9 0.253 VPS4A/ENSG00000132612.13 0.253 DNAJB4/ENSG00000162616.8 0.252 NPRL2/ENSG00000114388.8 0.252 RAD1/ENSG00000113456.14 0.251 WDR89/ENSG00000140006.7 0.251 SLC25A26/ENSG00000144741.12 0.251 ZNF511/ENSG00000198546.10 0.251 IMPA1/ENSG00000133731.5 0.251 NAT10/ENSG00000135372.4 0.251 SLC25A14/ENSG00000102078.11 0.251 CCNB1/ENSG00000134057.10 0.25 SETD5/ENSG00000168137.11 Overrepresented GO terms in EP #3: Term Pvalue amide biosynthetic process 8.62E-51 peptide metabolic process 3.31E-49 cellular nitrogen compound metabolic process 9.61E-41 organonitrogen compound biosynthetic process 1.68E-38 mitochondrial translational elongation 3.61E-37 mitochondrial translational termination 2.20E-36 "RNA splicing, via transesterification reactions " 1.24E-35 mRNA metabolic process 2.93E-32 organic substance metabolic process 7.59E-29 mitochondrion organization 3.89E-26 protein complex subunit organization 1.43E-25 cellular biosynthetic process 1.20E-24 nucleic acid metabolic process 1.23E-23 "mRNA splicing, via spliceosome " 4.43E-23 macromolecular complex disassembly 2.01E-22 cellular protein complex disassembly 2.19E-22 cellular component organization or biogenesis 9.95E-21 ribonucleoprotein complex subunit organization 4.34E-20 macromolecule biosynthetic process 6.67E-19 regulation of mRNA stability 3.94E-18 posttranscriptional regulation of gene expression 5.77E-18 ribonucleoprotein complex biogenesis 5.47E-17 cellular macromolecular complex assembly 7.36E-16 RNA localization 3.26E-15 tRNA metabolic process 5.62E-15 cellular macromolecule metabolic process 1.11E-14 RNA processing 5.00E-14 tRNA aminoacylation for protein translation 5.66E-14 regulation of cellular amino acid metabolic process 6.05E-13 amino acid activation 6.05E-13 RNA transport 1.08E-12 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.67E-12 negative regulation of protein modification by small protein conjugation or removal 1.59E-11 negative regulation of ubiquitin-protein transferase activity 1.65E-11 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition 1.87E-11 primary metabolic process 2.36E-11 anaphase-promoting complex-dependent catabolic process 3.99E-11 mRNA export from nucleus 6.25E-11 protein folding 1.15E-10 cellular process 1.80E-10 nucleobase-containing compound transport 2.31E-10 regulation of ubiquitin protein ligase activity 2.34E-10 carboxylic acid metabolic process 3.30E-10 positive regulation of ubiquitin-protein transferase activity 3.66E-10 transcription-coupled nucleotide-excision repair 4.85E-10 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 4.93E-10 ribonucleoprotein complex export from nucleus 5.71E-10 termination of RNA polymerase II transcription 6.26E-10 gene silencing by RNA 9.98E-10 "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent " 1.00E-09 regulation of translational initiation 1.51E-09 macromolecule catabolic process 1.81E-09 nucleocytoplasmic transport 3.12E-09 cellular amine metabolic process 3.18E-09 ncRNA metabolic process 4.08E-09 positive regulation of telomerase RNA localization to Cajal body 1.22E-08 protein sumoylation 1.25E-08 organic acid metabolic process 1.92E-08 positive regulation of protein localization to Cajal body 3.03E-08 formation of translation preinitiation complex 3.57E-08 RNA localization to Cajal body 3.66E-08 telomerase RNA localization 3.66E-08 establishment of protein localization to organelle 4.60E-08 nucleic acid phosphodiester bond hydrolysis 1.20E-07 protein localization to nuclear body 2.55E-07 positive regulation of establishment of protein localization to telomere 2.55E-07 positive regulation of protein modification by small protein conjugation or removal 2.67E-07 DNA repair 3.28E-07 RNA catabolic process 3.67E-07 tRNA export from nucleus 3.68E-07 regulation of cell cycle phase transition 3.74E-07 regulation of cellular protein catabolic process 3.90E-07 regulation of cellular response to heat 4.10E-07 RNA capping 4.23E-07 7-methylguanosine mRNA capping 6.10E-07 transcription elongation from RNA polymerase II promoter 7.13E-07 stimulatory C-type lectin receptor signaling pathway 7.67E-07 modification-dependent macromolecule catabolic process 8.68E-07 spliceosomal snRNP assembly 1.02E-06 antigen processing and presentation of peptide antigen via MHC class I 1.04E-06 "regulation of protein localization to chromosome, telomeric region " 1.21E-06 protein polyubiquitination 1.31E-06 rRNA processing 1.64E-06 mitotic cell cycle process 2.21E-06 regulation of chromosome organization 2.32E-06 ncRNA transcription 2.76E-06 intracellular transport 2.83E-06 regulation of establishment of protein localization to chromosome 4.09E-06 "Wnt signaling pathway, planar cell polarity pathway " 4.17E-06 intracellular transport of virus 4.33E-06 cellular component assembly 4.44E-06 multi-organism transport 5.16E-06 multi-organism cellular localization 5.67E-06 positive regulation of proteolysis involved in cellular protein catabolic process 6.35E-06 aromatic compound catabolic process 6.49E-06 heterocycle catabolic process 6.74E-06 mitotic nuclear envelope disassembly 7.04E-06 snRNA metabolic process 7.26E-06 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 8.64E-06 response to heat 9.32E-06 positive regulation of cellular catabolic process 1.10E-05 NIK/NF-kappaB signaling 1.14E-05 mRNA 3'-end processing 1.28E-05 cellular nitrogen compound catabolic process 1.37E-05 membrane disassembly 1.39E-05 regulation of mitotic cell cycle 1.41E-05 Fc-epsilon receptor signaling pathway 1.45E-05 organic cyclic compound catabolic process 1.60E-05 multi-organism cellular process 1.69E-05 transcription elongation from RNA polymerase I promoter 2.14E-05 termination of RNA polymerase I transcription 2.14E-05 ribosomal small subunit biogenesis 2.27E-05 establishment of planar polarity 2.66E-05 "symbiosis, encompassing mutualism through parasitism " 2.91E-05 positive regulation of protein catabolic process 3.49E-05 ubiquitin-dependent protein catabolic process 4.67E-05 maturation of 5.8S rRNA 4.86E-05 transcription initiation from RNA polymerase I promoter 4.86E-05 positive regulation of canonical Wnt signaling pathway 5.80E-05 regulation of catabolic process 6.41E-05 nucleoside metabolic process 6.66E-05 cellular ketone metabolic process 6.75E-05 nuclear polyadenylation-dependent tRNA catabolic process 7.72E-05 cytoplasmic translation 8.46E-05 regulation of mRNA processing 8.83E-05 protein-DNA complex subunit organization 9.52E-05 nuclear envelope organization 0.000110193 protein complex assembly 0.000117125 maturation of LSU-rRNA 0.000121934 rRNA modification 0.000135073 U4 snRNA 3'-end processing 0.000139168 protein import 0.00014305 "RNA phosphodiester bond hydrolysis, exonucleolytic " 0.000146115 chaperone-mediated protein folding 0.000155315 ribosome biogenesis 0.00017505 regulation of RNA splicing 0.000181745 T cell receptor signaling pathway 0.000193063 translation 0.000200041 snRNA transcription from RNA polymerase II promoter 0.000266328 cellular response to stress 0.000273573 nuclear import 0.000310398 protein stabilization 0.000374707 RNA-dependent DNA biosynthetic process 0.000385074 "nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' " 0.000391364 nucleoside monophosphate metabolic process 0.000426935 'de novo' IMP biosynthetic process 0.00043481 polyadenylation-dependent ncRNA catabolic process 0.00043481 nuclear ncRNA surveillance 0.00043481 nuclear polyadenylation-dependent rRNA catabolic process 0.00043481 protein localization to cytoplasmic stress granule 0.00043481 protein localization to nucleus 0.000527809 antigen processing and presentation of exogenous peptide antigen 0.000564871 spliceosomal complex assembly 0.000568098 telomere organization 0.000570825 RNA splicing 0.00061504 nuclear-transcribed mRNA poly(A) tail shortening 0.000694839 coenzyme metabolic process 0.000713194 ribosome assembly 0.000720249 cofactor biosynthetic process 0.000777883 establishment of ribosome localization 0.000917236 positive regulation of translation 0.001018638 cleavage involved in rRNA processing 0.001050586 histone mRNA metabolic process 0.001050586 intracellular protein transmembrane transport 0.001062033 negative regulation of translation 0.001189486 RNA 3'-end processing 0.001336276 snoRNA 3'-end processing 0.001429037 DNA replication 0.001535151 positive regulation of viral process 0.001906089 "alternative mRNA splicing, via spliceosome " 0.001988099 protein peptidyl-prolyl isomerization 0.002223712 nucleobase-containing compound metabolic process 0.002263855 cellular respiration 0.002272832 organelle organization 0.002406739 chromosome separation 0.002503766 regulation of nitrogen compound metabolic process 0.002557444 regulation of translational fidelity 0.00262016 protein import into mitochondrial matrix 0.00262016 translational elongation 0.0026465 nuclear chromosome segregation 0.002953439 purine ribonucleoside monophosphate metabolic process 0.003203558 nuclear mRNA surveillance 0.003547934 rRNA-containing ribonucleoprotein complex export from nucleus 0.003547934 "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) " 0.003578819 snRNA processing 0.003805351 regulation of DNA metabolic process 0.003894745 tumor necrosis factor-mediated signaling pathway 0.004173064 negative regulation of protein metabolic process 0.0042705 negative regulation of metabolic process 0.004473032 transcription initiation from RNA polymerase II promoter 0.00472988 nucleobase-containing compound biosynthetic process 0.004866104 purine ribonucleoside metabolic process 0.004866193 ribosomal small subunit export from nucleus 0.004951285 regulation of telomere maintenance via telomere lengthening 0.004991844 nuclear-transcribed mRNA catabolic process 0.005344766 negative regulation of mRNA metabolic process 0.005410151 macromolecule methylation 0.005481607 regulation of translation 0.005538605 positive regulation of viral transcription 0.006023019 "DNA damage response, detection of DNA damage " 0.007001472 RNA secondary structure unwinding 0.007561079 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly 0.007563136 aldehyde catabolic process 0.007563136 DNA-templated transcriptional preinitiation complex assembly 0.007665141 regulation of morphogenesis of an epithelium 0.007820563 regulation of mitochondrion organization 0.007851401 ATP-dependent chromatin remodeling 0.007961629 protein export from nucleus 0.008720801 nucleobase metabolic process 0.008968088 regulation of mitotic metaphase/anaphase transition 0.009418739 "negative regulation of mRNA splicing, via spliceosome " 0.00948373 cellular macromolecule localization 0.01013174 RNA surveillance 0.010140665 alpha-amino acid biosynthetic process 0.010442538 cell cycle 0.010643751 ribonucleoside biosynthetic process 0.011223697 positive regulation of telomere maintenance via telomerase 0.01317872 RNA stabilization 0.01317872 catabolic process 0.013193745 ribosomal large subunit biogenesis 0.013459882 'de novo' protein folding 0.01366843 rRNA methylation 0.01366843 ribosomal large subunit export from nucleus 0.013984234 methylglyoxal metabolic process 0.013984234 protein import into mitochondrial outer membrane 0.013984234 cellular lipid biosynthetic process 0.013984234 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter 0.013984234 tRNA 5'-leader removal 0.014209036 nucleobase-containing small molecule interconversion 0.014263516 mRNA polyadenylation 0.01430221 formation of cytoplasmic translation initiation complex 0.014326552 U1 snRNA 3'-end processing 0.014326552 U5 snRNA 3'-end processing 0.014326552 purine nucleoside triphosphate metabolic process 0.014452293 histone H4 acetylation 0.014767465 cap-independent translational initiation 0.015851944 nuclear pore organization 0.015851944 glycosyl compound biosynthetic process 0.016482341 "RNA phosphodiester bond hydrolysis, endonucleolytic " 0.017446337 positive regulation of telomere maintenance 0.017447746 proteasomal protein catabolic process 0.017792718 tricarboxylic acid cycle 0.018973118 binding of sperm to zona pellucida 0.018973118 protein modification by small protein conjugation 0.019347829 mitochondrial respiratory chain complex I assembly 0.01948073 ribonucleoside monophosphate biosynthetic process 0.020428398 viral transcription 0.020721164 negative regulation of sister chromatid segregation 0.021562942 viral gene expression 0.022524394 mitotic sister chromatid segregation 0.022787113 protein modification by small protein removal 0.022856013 nucleoside salvage 0.023791015 positive regulation of cellular protein localization 0.024851172 nucleotide metabolic process 0.026216458 cellular protein metabolic process 0.026947376 ribonucleoside triphosphate metabolic process 0.027657925 methylation 0.028122741 IRES-dependent viral translational initiation 0.030724498 protein localization to nuclear envelope 0.030724498 gene expression 0.031042569 peptidyl-amino acid modification 0.031412989 "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) " 0.0338719 DNA recombination 0.034338942 G1/S transition of mitotic cell cycle 0.034544492 monosaccharide biosynthetic process 0.034969244 positive regulation of proteasomal protein catabolic process 0.034969244 generation of precursor metabolites and energy 0.036465968 tRNA modification 0.037826946 protein targeting to mitochondrion 0.039114406 lactate metabolic process 0.039419979 snoRNA metabolic process 0.039419979 RNA interference 0.039419979 negative regulation of intracellular estrogen receptor signaling pathway 0.039419979 mitotic spindle checkpoint 0.041042432 negative regulation of metaphase/anaphase transition of cell cycle 0.041042432 negative regulation of mitotic sister chromatid separation 0.041042432 respiratory electron transport chain 0.041702906 toxin transport 0.041876697 antigen processing and presentation 0.042840749 "regulation of gene expression, epigenetic " 0.042969727 tRNA processing 0.047378547 sister chromatid cohesion 0.047468383 "regulation of DNA-templated transcription, elongation " 0.047941995 inner mitochondrial membrane organization 0.048541467 negative regulation of canonical Wnt signaling pathway 0.049555546 --------------------------------------------- "EP #4: 158 cells, 171 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.0428571428571429, St4_3_: 0.0229885057471264, stage4: 0.0857142857142857, St5_3_: 0.73972602739726, stage5_: 0.390625, stage6.2_: 0.475609756097561, stage6.7_: 0.328947368421053, stage6.14_: 0.0597014925373134, " Top Genes: 2.058 RP11-834C11.4/ENSG00000250742.1 1.95 GSTA1/ENSG00000243955.1 1.536 MEIS1/ENSG00000143995.14 1.482 APOC1/ENSG00000130208.5 1.391 SAT1/ENSG00000130066.12 1.367 GRB14/ENSG00000115290.5 1.192 TMEM176B/ENSG00000106565.13 1.175 LINC00261/ENSG00000259974.1 1.147 ANXA2/ENSG00000182718.11 1.146 RGS4/ENSG00000117152.9 1.113 SHH/ENSG00000164690.3 1.081 B3GNT7/ENSG00000156966.6 1.06 CDC42EP3/ENSG00000163171.6 1.022 AMBP/ENSG00000106927.7 1.012 AC132217.4/ENSG00000240801.1 1.008 CPM/ENSG00000135678.7 0.994 IGF2/ENSG00000167244.12 0.986 RARRES2/ENSG00000106538.5 0.951 S100A6/ENSG00000197956.5 0.944 FXYD3/ENSG00000089356.12 0.939 PDHA1/ENSG00000131828.9 0.922 ZFP36L1/ENSG00000185650.8 0.916 CTC-340A15.2/ENSG00000241956.5 0.882 ANXA4/ENSG00000196975.9 0.851 TRIM45/ENSG00000134253.5 0.849 PDLIM1/ENSG00000107438.4 0.845 EZR/ENSG00000092820.13 0.818 MECOM/ENSG00000085276.13 0.812 NREP/ENSG00000134986.9 0.803 VSIG1/ENSG00000101842.9 0.779 SPINK1/ENSG00000164266.6 0.773 CTC-535M15.1/ENSG00000253512.1 0.725 IRF2BP2/ENSG00000168264.6 0.716 RAI14/ENSG00000039560.9 0.706 CD9/ENSG00000010278.7 0.697 ANXA3/ENSG00000138772.8 0.685 TMEM176A/ENSG00000002933.3 0.68 ADA/ENSG00000196839.8 0.67 ETNK1/ENSG00000139163.11 0.667 FDFT1/ENSG00000079459.8 0.664 FZD5/ENSG00000163251.3 0.659 GSTA4/ENSG00000170899.6 0.623 LRAT/ENSG00000121207.7 0.618 EHBP1/ENSG00000115504.10 0.617 SPTBN1/ENSG00000115306.11 0.612 TPD52/ENSG00000076554.11 0.607 LAMB2/ENSG00000172037.9 0.599 CDH1/ENSG00000039068.13 0.595 SOX11/ENSG00000176887.5 0.589 MUC1/ENSG00000185499.12 0.57 TTC39C/ENSG00000168234.8 0.567 CSMD3/ENSG00000164796.13 0.567 SKAP2/ENSG00000005020.8 0.561 PRSS1/ENSG00000204983.8 0.561 MAN1A2/ENSG00000198162.8 0.551 TTLL7/ENSG00000137941.12 0.549 MFAP2/ENSG00000117122.9 0.543 OCLN/ENSG00000197822.6 0.543 ATP1A1/ENSG00000163399.11 0.54 INSIG2/ENSG00000125629.10 0.536 CXCR7/ENSG00000144476.5 0.536 SPAG16/ENSG00000144451.14 0.53 ABP1/ENSG00000002726.15 0.528 TSC22D1/ENSG00000102804.10 0.521 POGLUT1/ENSG00000163389.6 0.521 RP11-96D1.11/ENSG00000262160.1 0.519 IDH1/ENSG00000138413.9 0.508 MTTP/ENSG00000138823.8 0.507 C9ORF38/ENSG00000215066.3 0.505 FAM214A/ENSG00000047346.8 0.499 ASAH1/ENSG00000104763.13 0.497 TMEM14A/ENSG00000096092.5 0.492 FOXA1/ENSG00000129514.4 0.485 CD47/ENSG00000196776.10 0.484 ZNF165/ENSG00000197279.3 0.471 RP1-152L7.5/ENSG00000216775.2 0.47 C12ORF75/ENSG00000235162.4 0.464 SLC39A11/ENSG00000133195.7 0.457 TAGLN2/ENSG00000158710.10 0.455 PAM/ENSG00000145730.16 0.453 GCNT1/ENSG00000187210.8 0.452 MTUS1/ENSG00000129422.9 0.444 FTSJ1/ENSG00000068438.10 0.433 RP11-379K17.12/ENSG00000268220.1 0.429 JARID2/ENSG00000008083.9 0.424 GPATCH8/ENSG00000186566.7 0.422 C3ORF58/ENSG00000181744.4 0.417 GATA4/ENSG00000136574.13 0.416 PLSCR1/ENSG00000188313.8 0.413 TGIF1/ENSG00000177426.15 0.41 FRZB/ENSG00000162998.4 0.409 TMEM97/ENSG00000109084.9 0.409 HOTAIRM1/ENSG00000233429.5 0.408 C19ORF33/ENSG00000167644.7 0.404 MEIS2/ENSG00000134138.14 0.399 NTS/ENSG00000133636.6 0.399 NFE2L2/ENSG00000116044.11 0.399 SNX5/ENSG00000089006.11 0.398 CCNYL1/ENSG00000163249.5 0.397 CCDC12/ENSG00000160799.7 0.396 MAGI1/ENSG00000151276.17 0.396 ZCCHC9/ENSG00000131732.7 0.393 PRSS3P2/ENSG00000250606.4 0.388 WLS/ENSG00000116729.9 0.387 ID3/ENSG00000117318.8 0.386 C6ORF211/ENSG00000146476.6 0.385 TTTY14/ENSG00000176728.3 0.383 EFEMP1/ENSG00000115380.14 0.38 UHRF2/ENSG00000147854.12 0.379 TMEM248/ENSG00000106609.11 0.377 PTPRD/ENSG00000153707.11 0.376 STARD4-AS1/ENSG00000246859.2 0.371 SCNN1A/ENSG00000111319.8 0.366 AC007098.1/ENSG00000226605.1 0.365 MDK/ENSG00000110492.11 0.365 MTAP/ENSG00000099810.13 0.365 MCM3/ENSG00000112118.12 0.361 ST3GAL6/ENSG00000064225.8 0.359 KLF5/ENSG00000102554.9 0.351 DNAJB1/ENSG00000132002.3 0.348 IGFBP5/ENSG00000115461.4 0.347 ONECUT1/ENSG00000169856.6 0.346 SDC4/ENSG00000124145.5 0.341 PRCP/ENSG00000137509.5 0.34 CLDN18/ENSG00000066405.8 0.336 CDH26/ENSG00000124215.12 0.329 AKAP7/ENSG00000118507.11 0.329 PTPN13/ENSG00000163629.8 0.328 IGFBP6/ENSG00000167779.3 0.324 SEC23A/ENSG00000100934.10 0.324 FRYL/ENSG00000075539.9 0.319 RP11-30B1.1/ENSG00000224593.1 0.317 CCNB1IP1/ENSG00000100814.13 0.317 MDM2/ENSG00000135679.17 0.315 PLTP/ENSG00000100979.10 0.314 SYPL1/ENSG00000008282.3 0.314 MITD1/ENSG00000158411.6 0.313 MYLIP/ENSG00000007944.10 0.304 LAMP2/ENSG00000005893.11 0.303 LITAF/ENSG00000189067.8 0.3 ZNF761/ENSG00000160336.10 0.299 TTF2/ENSG00000116830.6 0.299 PPP1R3B/ENSG00000173281.4 0.299 STT3B/ENSG00000163527.5 0.296 RP11-6N17.6/ENSG00000264019.1 0.296 GYPC/ENSG00000136732.10 0.296 AC005154.6/ENSG00000196295.6 0.294 HS3ST3B1/ENSG00000125430.4 0.293 MET/ENSG00000105976.10 0.29 ABCC5/ENSG00000114770.12 0.287 C5ORF42/ENSG00000197603.9 0.287 IQCA1/ENSG00000132321.12 0.282 SELENBP1/ENSG00000143416.15 0.281 S100A4/ENSG00000196154.7 0.279 MICAL1/ENSG00000135596.13 0.276 IRF9/ENSG00000213928.4 0.275 RBP1/ENSG00000114115.5 0.274 COL22A1/ENSG00000169436.12 0.274 LGALS3BP/ENSG00000108679.7 0.274 PIGT/ENSG00000124155.11 0.269 PALLD/ENSG00000129116.13 0.269 PDE3A/ENSG00000172572.6 0.269 CDCP1/ENSG00000163814.3 0.268 ADM/ENSG00000148926.5 0.264 UCP2/ENSG00000175567.3 0.262 LIFR/ENSG00000113594.5 0.261 ACSL3/ENSG00000123983.9 0.261 KIAA1551/ENSG00000174718.7 0.257 TAPBP/ENSG00000231925.7 0.254 PELI2/ENSG00000139946.5 0.254 TMEM41B/ENSG00000166471.6 Overrepresented GO terms in EP #4: Term Pvalue single-multicellular organism process 0.000132926 negative regulation of hemopoiesis 0.000242012 epithelium development 0.000845214 digestive system development 0.001492887 anatomical structure morphogenesis 0.001725823 cardiovascular system development 0.002798254 epithelial-mesenchymal signaling involved in prostate gland development 0.003132912 cellular developmental process 0.003493285 blood vessel development 0.005511149 negative regulation of cell differentiation 0.006474172 response to organic cyclic compound 0.006826188 embryonic eye morphogenesis 0.006847883 cell adhesion 0.00704957 embryo development 0.007626448 embryonic digestive tract development 0.007769603 angiogenesis 0.009226394 protein-lipid complex subunit organization 0.009875884 mesenchyme development 0.009959927 gland development 0.010384071 terpenoid metabolic process 0.011304108 post-embryonic animal organ development 0.012112865 epithelial cell development 0.01217291 lung alveolus development 0.015270196 response to oxygen-containing compound 0.017841582 sulfur compound biosynthetic process 0.017934387 negative regulation of dendritic cell differentiation 0.018566966 tube development 0.019864521 stem cell differentiation 0.023837083 plasma lipoprotein particle assembly 0.025098517 receptor internalization 0.026120092 response to hormone 0.02835809 regulation of low-density lipoprotein particle receptor catabolic process 0.030754832 response to drug 0.032218792 response to wounding 0.033606179 lipid metabolic process 0.033893178 labyrinthine layer morphogenesis 0.033980354 tissue morphogenesis 0.037771028 post-embryonic eye morphogenesis 0.045849038 --------------------------------------------- "EP #5: 64 cells, 904 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 1, stage2_: 0.0147058823529412, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0, stage5_: 0, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0, " Top Genes: 3.889 CER1/ENSG00000147869.4 3.88 IFITM1/ENSG00000185885.11 3.88 TDGF1/ENSG00000241186.3 3.797 RP11-426L16.8/ENSG00000215866.3 3.795 IFITM3/ENSG00000142089.11 3.765 RP11-148B6.1/ENSG00000249532.1 3.501 CTSL2/ENSG00000136943.6 3.412 AL590714.1/ENSG00000268387.1 3.324 OTX2/ENSG00000165588.12 3.31 SHISA2/ENSG00000180730.4 3.204 SLC2A3/ENSG00000059804.11 3.111 ANXA2/ENSG00000182718.11 3.086 LINC00458/ENSG00000234787.2 3.023 APOA2/ENSG00000158874.6 2.89 RP11-161H23.5/ENSG00000258232.2 2.884 LDHA/ENSG00000134333.9 2.862 LAPTM4B/ENSG00000104341.12 2.696 ZIC2/ENSG00000043355.6 2.693 SERPINB9/ENSG00000170542.5 2.683 PTGR1/ENSG00000106853.12 2.629 AC107016.1/ENSG00000225410.1 2.602 LEFTY2/ENSG00000143768.7 2.575 CTD-2501M5.1/ENSG00000253507.1 2.534 WARS/ENSG00000140105.12 2.429 APOC1/ENSG00000130208.5 2.411 RP11-431J24.2/ENSG00000238178.2 2.356 MGST2/ENSG00000085871.4 2.323 CCKBR/ENSG00000110148.5 2.317 RP11-3P17.5/ENSG00000269888.1 2.283 PHACTR2/ENSG00000112419.10 2.233 CXCR4/ENSG00000121966.6 2.19 L1TD1/ENSG00000240563.1 2.14 FAM159B/ENSG00000145642.7 2.136 GJA1/ENSG00000152661.7 2.126 PLSCR1/ENSG00000188313.8 2.052 RHOBTB3/ENSG00000164292.8 2.051 FZD5/ENSG00000163251.3 2.037 SFRP1/ENSG00000104332.7 2.021 SPARC/ENSG00000113140.6 2.019 FAM184A/ENSG00000111879.14 2.004 CNTNAP2/ENSG00000174469.13 1.99 PRDX5/ENSG00000126432.9 1.963 MFAP4/ENSG00000166482.7 1.961 TRMT44/ENSG00000155275.14 1.891 LEPREL1/ENSG00000090530.5 1.87 PDLIM1/ENSG00000107438.4 1.862 PGAM1/ENSG00000171314.8 1.859 GSTO1/ENSG00000148834.8 1.854 LEFTY1/ENSG00000243709.1 1.842 RP11-114G22.1/ENSG00000256995.2 1.838 VAMP8/ENSG00000118640.6 1.823 S100A10/ENSG00000197747.4 1.817 RP11-449P1.1/ENSG00000256923.1 1.817 KIT/ENSG00000157404.11 1.808 CDH2/ENSG00000170558.4 1.797 LIN28A/ENSG00000131914.6 1.792 GPC4/ENSG00000076716.7 1.775 DHCR24/ENSG00000116133.7 1.762 CYP26A1/ENSG00000095596.7 1.742 CCNG1/ENSG00000113328.14 1.726 SERPINE2/ENSG00000135919.8 1.723 CALM3/ENSG00000160014.12 1.721 PKM/ENSG00000067225.13 1.72 UCHL1/ENSG00000154277.8 1.712 CA2/ENSG00000104267.5 1.705 APLP2/ENSG00000084234.12 1.695 MYCT1/ENSG00000120279.6 1.693 AK4/ENSG00000162433.10 1.693 BNIP3/ENSG00000176171.7 1.684 FAM126A/ENSG00000122591.7 1.665 PSAT1/ENSG00000135069.9 1.662 KRT18/ENSG00000111057.6 1.661 CWC27/ENSG00000153015.11 1.648 MRPL22/ENSG00000082515.12 1.636 ZNF90/ENSG00000213988.5 1.62 CTC-260E6.6/ENSG00000267383.2 1.612 AKR1B1/ENSG00000085662.9 1.601 PRDM1/ENSG00000057657.10 1.595 MIF/ENSG00000240972.1 1.574 PDHA1/ENSG00000131828.9 1.569 CTSC/ENSG00000109861.11 1.562 TOMM20/ENSG00000173726.6 1.559 LRIG3/ENSG00000139263.7 1.555 NODAL/ENSG00000156574.5 1.549 FGF17/ENSG00000158815.6 1.515 NPC2/ENSG00000119655.4 1.51 MRPS6/ENSG00000243927.1 1.503 YPEL5/ENSG00000119801.8 1.49 HAS2/ENSG00000170961.6 1.483 MGST1/ENSG00000008394.7 1.477 PLRG1/ENSG00000171566.7 1.458 CAMKMT/ENSG00000143919.10 1.455 EFNA5/ENSG00000184349.8 1.449 ACAT2/ENSG00000120437.7 1.438 SAMD3/ENSG00000164483.12 1.438 RP5-857K21.11/ENSG00000198744.5 1.432 SERINC3/ENSG00000132824.9 1.429 MAGED2/ENSG00000102316.11 1.42 C6ORF211/ENSG00000146476.6 1.418 PGK1/ENSG00000102144.9 1.414 MDH2/ENSG00000146701.6 1.398 S100A11/ENSG00000163191.5 1.396 SEMA3E/ENSG00000170381.8 1.395 DBNDD2/ENSG00000244274.3 1.393 NUDT4/ENSG00000173598.9 1.388 AC011558.5/ENSG00000267020.1 1.386 KRT8/ENSG00000170421.7 1.384 ITGB5/ENSG00000082781.6 1.356 TMEM141/ENSG00000244187.2 1.35 RAP2B/ENSG00000181467.2 1.333 FN1/ENSG00000115414.14 1.332 TRDN/ENSG00000186439.8 1.329 SEC11C/ENSG00000166562.4 1.312 GLIPR2/ENSG00000122694.11 1.308 MSH6/ENSG00000116062.8 1.292 AC005276.1/ENSG00000197462.3 1.271 ATPAF2/ENSG00000171953.11 1.27 TUBA1C/ENSG00000167553.10 1.266 MAP1B/ENSG00000131711.10 1.261 ENSA/ENSG00000143420.13 1.245 IDH1/ENSG00000138413.9 1.242 PRSS1/ENSG00000204983.8 1.238 DMKN/ENSG00000161249.16 1.236 SH3BGRL3/ENSG00000142669.9 1.217 BCAT1/ENSG00000060982.10 1.217 TMEM14B/ENSG00000137210.8 1.204 CCDC141/ENSG00000163492.9 1.204 PIM2/ENSG00000102096.9 1.197 FERMT2/ENSG00000073712.9 1.197 ACOX3/ENSG00000087008.11 1.196 PSIP1/ENSG00000164985.10 1.193 TUBB2A/ENSG00000137267.5 1.188 CTC-425F1.4/ENSG00000267458.1 1.163 ZC3HAV1/ENSG00000105939.8 1.163 CNN2/ENSG00000064666.9 1.163 HMGA1/ENSG00000137309.15 1.161 MTHFD2/ENSG00000065911.7 1.15 TGIF1/ENSG00000177426.15 1.146 MANEA/ENSG00000172469.10 1.132 MTRNR2L2/ENSG00000271043.1 1.13 DAAM1/ENSG00000100592.11 1.129 NFKBIA/ENSG00000100906.6 1.127 SSBP3/ENSG00000157216.11 1.125 TRMT112/ENSG00000173113.2 1.118 FDFT1/ENSG00000079459.8 1.115 SALL4/ENSG00000101115.8 1.107 AP000350.4/ENSG00000218537.1 1.098 MAGED1/ENSG00000179222.12 1.098 GTF2I/ENSG00000077809.8 1.097 ANGPT2/ENSG00000091879.9 1.088 ARL6IP1/ENSG00000170540.10 1.084 CD200/ENSG00000091972.13 1.082 AC040977.1/ENSG00000269871.1 1.081 MYO10/ENSG00000145555.10 1.081 CCDC90B/ENSG00000137500.5 1.08 ZBTB8OS/ENSG00000176261.11 1.079 SEC61G/ENSG00000132432.9 1.073 EOMES/ENSG00000163508.8 1.072 SLC3A2/ENSG00000168003.12 1.07 TMSB15B/ENSG00000158427.10 1.057 FAM162A/ENSG00000114023.11 1.053 UQCRB/ENSG00000156467.5 1.052 RPA1/ENSG00000132383.7 1.048 TOMM7/ENSG00000196683.6 1.042 PPFIBP2/ENSG00000166387.7 1.037 NXN/ENSG00000167693.12 1.036 PLAUR/ENSG00000011422.7 1.034 TUBB4B/ENSG00000188229.5 1.032 CST1/ENSG00000170373.4 1.03 MYL6B/ENSG00000196465.5 1.028 MANF/ENSG00000145050.11 1.027 PPFIA1/ENSG00000131626.11 1.024 S100A13/ENSG00000189171.8 1.023 DLC1/ENSG00000164741.10 1.021 ECH1/ENSG00000104823.4 1.009 HDLBP/ENSG00000115677.12 1.006 ZMYM2/ENSG00000121741.11 1.006 WFDC2/ENSG00000101443.13 1.001 RBM8A/ENSG00000131795.7 1 EIF4EBP1/ENSG00000187840.4 0.999 ME2/ENSG00000082212.7 0.998 PODXL/ENSG00000128567.12 0.995 PDIA6/ENSG00000143870.8 0.993 PFN1/ENSG00000108518.7 0.989 TMEM50B/ENSG00000142188.12 0.986 CLTC/ENSG00000141367.6 0.985 KRT19/ENSG00000171345.9 0.985 TNFAIP8/ENSG00000145779.6 0.983 PHGDH/ENSG00000092621.7 0.982 CXCR7/ENSG00000144476.5 0.981 "NME1-NME2,NME2/ENSG00000011052.16" 0.976 RBM3/ENSG00000102317.13 0.974 VAT1/ENSG00000108828.11 0.972 ERBB4/ENSG00000178568.9 0.972 CALB1/ENSG00000104327.3 0.971 PFDN4/ENSG00000101132.5 0.964 SLC5A9/ENSG00000117834.8 0.963 NME4/ENSG00000103202.8 0.962 FZD7/ENSG00000155760.1 0.961 PPAP2A/ENSG00000067113.12 0.96 SHMT2/ENSG00000182199.6 0.959 CPE/ENSG00000109472.9 0.957 CTC-260E6.10/ENSG00000271524.1 0.956 PERP/ENSG00000112378.10 0.955 CCNYL1/ENSG00000163249.5 0.95 CPNE1/ENSG00000214078.7 0.945 ASNS/ENSG00000070669.12 0.944 TRAPPC2L/ENSG00000167515.6 0.944 IQGAP1/ENSG00000140575.8 0.943 SDCBP/ENSG00000137575.7 0.94 TMEM219/ENSG00000149932.12 0.939 PAN3/ENSG00000152520.9 0.936 FARP1/ENSG00000152767.11 0.935 IFITM2/ENSG00000185201.12 0.932 DPPA4/ENSG00000121570.8 0.93 FST/ENSG00000134363.7 0.928 UCP2/ENSG00000175567.3 0.925 SRGAP2/ENSG00000163486.8 0.924 ATP6V1E1/ENSG00000131100.8 0.922 FLVCR1/ENSG00000162769.8 0.921 DDIT3/ENSG00000175197.5 0.919 RNF181/ENSG00000168894.5 0.919 PRPF40A/ENSG00000196504.11 0.913 DNMT3A/ENSG00000119772.12 0.911 CELF2/ENSG00000048740.12 0.91 CEP70/ENSG00000114107.4 0.907 HIGD1A/ENSG00000181061.9 0.904 CALR/ENSG00000179218.8 0.903 TSTD1/ENSG00000215845.6 0.9 CNDP2/ENSG00000133313.10 0.9 VCP/ENSG00000165280.11 0.899 RP11-511B23.1/ENSG00000257345.2 0.894 GTF2A2/ENSG00000140307.6 0.885 CTD-2311M21.2/ENSG00000260266.1 0.884 MSH2/ENSG00000095002.8 0.877 DBI/ENSG00000155368.12 0.874 COPB2/ENSG00000184432.4 0.871 DERA/ENSG00000023697.8 0.863 SLC7A3/ENSG00000165349.7 0.862 ATP6V1B2/ENSG00000147416.6 0.855 PDIA4/ENSG00000155660.6 0.853 PDHB/ENSG00000168291.8 0.851 MCM6/ENSG00000076003.4 0.851 RPS3AP34/ENSG00000242607.1 0.85 NCOA4/ENSG00000138293.15 0.848 PRKD3/ENSG00000115825.5 0.847 MIXL1/ENSG00000185155.7 0.844 UQCRC1/ENSG00000010256.6 0.836 PSMD9/ENSG00000110801.8 0.835 GEMIN7/ENSG00000142252.6 0.833 TRAPPC1/ENSG00000170043.7 0.827 RPS2/ENSG00000140988.11 0.827 HSPA5/ENSG00000044574.7 0.825 RP11-632C17__A.1/ENSG00000230202.1 0.818 MAP2K6/ENSG00000108984.9 0.817 CDK7/ENSG00000134058.6 0.816 APOE/ENSG00000130203.5 0.816 C12ORF57/ENSG00000111678.5 0.815 SERPINB6/ENSG00000124570.13 0.813 DDT/ENSG00000099977.9 0.812 YARS/ENSG00000134684.6 0.811 CTD-2306M5.1/ENSG00000248605.1 0.811 CKS1B/ENSG00000173207.8 0.808 EIF3F/ENSG00000175390.8 0.806 ALDOA/ENSG00000149925.12 0.806 AC005062.2/ENSG00000243004.1 0.803 RP11-393B14.1/ENSG00000240024.1 0.8 SSR3/ENSG00000114850.2 0.796 CCND2/ENSG00000118971.3 0.793 ATP5H/ENSG00000167863.7 0.79 MTRNR2L9/ENSG00000255633.3 0.787 TMSB4XP8/ENSG00000187653.10 0.783 C3/ENSG00000125730.12 0.782 MRPS25/ENSG00000131368.3 0.781 SLC40A1/ENSG00000138449.6 0.779 CTD-2007L18.5/ENSG00000260808.1 0.779 MTRNR2L1/ENSG00000256618.1 0.778 HIATL1/ENSG00000148110.11 0.778 CAPNS1/ENSG00000126247.6 0.778 ADD1/ENSG00000087274.12 0.778 TMEM97/ENSG00000109084.9 0.776 LRRC16A/ENSG00000079691.15 0.776 CDA/ENSG00000158825.5 0.775 GPX3/ENSG00000211445.6 0.774 GLRX/ENSG00000173221.9 0.774 FUT8/ENSG00000033170.12 0.77 GLMN/ENSG00000174842.12 0.769 RAB25/ENSG00000132698.9 0.765 FLNB/ENSG00000136068.10 0.765 BST2/ENSG00000130303.8 0.765 TCF7L1/ENSG00000152284.4 0.764 ADH5/ENSG00000197894.6 0.76 COMMD2/ENSG00000114744.4 0.759 ATF4/ENSG00000128272.10 0.758 MTRNR2L8/ENSG00000255823.1 0.754 UBE2L3/ENSG00000185651.10 0.751 NR6A1/ENSG00000148200.12 0.75 RNASEK/ENSG00000219200.5 0.748 "PMF1,PMF1-BGLAP/ENSG00000160783.13" 0.747 CANX/ENSG00000127022.10 0.747 FRZB/ENSG00000162998.4 0.746 CRIP1/ENSG00000213145.5 0.743 BIK/ENSG00000100290.2 0.742 SALL1/ENSG00000103449.7 0.733 ATL2/ENSG00000119787.9 0.73 ERP29/ENSG00000089248.6 0.729 LRRFIP1/ENSG00000124831.14 0.728 RBM6/ENSG00000004534.10 0.728 ASH2L/ENSG00000129691.11 0.728 RP4-559A3.6/ENSG00000248322.1 0.724 FABP5/ENSG00000164687.6 0.722 PSME4/ENSG00000068878.10 0.721 SKIL/ENSG00000136603.9 0.719 NAMPT/ENSG00000105835.7 0.717 FAM174B/ENSG00000185442.7 0.714 XYLT2/ENSG00000015532.5 0.712 RAB18/ENSG00000099246.12 0.712 KLF8/ENSG00000102349.10 0.71 DNAJC15/ENSG00000120675.4 0.709 ESYT1/ENSG00000139641.8 0.707 TTC39B/ENSG00000155158.15 0.705 TRNAU1AP/ENSG00000180098.5 0.705 AKAP13/ENSG00000170776.15 0.704 PRDX6/ENSG00000117592.8 0.703 CFLAR/ENSG00000003402.14 0.699 TLN2/ENSG00000171914.10 0.695 RNA28S5/ENSG00000226958.1 0.695 RND2/ENSG00000108830.7 0.695 PCK2/ENSG00000100889.7 0.689 DDX39A/ENSG00000123136.10 0.688 AGL/ENSG00000162688.11 0.686 PTPN13/ENSG00000163629.8 0.685 GPSM2/ENSG00000121957.7 0.684 ATRX/ENSG00000085224.16 0.684 RCHY1/ENSG00000163743.9 0.682 SLC16A1/ENSG00000155380.7 0.68 BPTF/ENSG00000171634.12 0.679 MCC/ENSG00000171444.13 0.679 SMARCA5/ENSG00000153147.5 0.674 RP11-758I14.3/ENSG00000241358.1 0.671 SLC25A13/ENSG00000004864.9 0.671 EIF2S2/ENSG00000125977.6 0.669 PARD3/ENSG00000148498.11 0.669 UNC50/ENSG00000115446.7 0.669 PDE4DIP/ENSG00000178104.14 0.666 SREK1IP1/ENSG00000153006.9 0.665 TCF7L1-IT1/ENSG00000231134.1 0.664 ATP6V0D1/ENSG00000159720.7 0.663 SLU7/ENSG00000164609.5 0.656 TMEM123/ENSG00000152558.10 0.656 FGF13/ENSG00000129682.9 0.655 PALLD/ENSG00000129116.13 0.655 NUCKS1/ENSG00000069275.12 0.655 GCNT1/ENSG00000187210.8 0.653 RP11-946L20.4/ENSG00000253103.1 0.652 ESRP1/ENSG00000104413.11 0.648 RRP9/ENSG00000114767.6 0.648 TTC3/ENSG00000182670.9 0.647 GARS/ENSG00000106105.9 0.647 TPM2/ENSG00000198467.8 0.647 NPEPPS/ENSG00000141279.9 0.647 RNF5/ENSG00000204308.6 0.645 C14ORF119/ENSG00000179933.4 0.643 LAPTM4A/ENSG00000068697.6 0.641 BEX2/ENSG00000133134.7 0.64 MARCH3/ENSG00000173926.5 0.636 LEPREL1-AS1/ENSG00000225764.1 0.636 CCDC104/ENSG00000163001.7 0.635 GLB1/ENSG00000170266.11 0.634 AC010761.8/ENSG00000264577.1 0.633 HAX1/ENSG00000143575.10 0.633 MKRN1/ENSG00000133606.6 0.632 EFCAB14/ENSG00000159658.6 0.632 COPZ1/ENSG00000111481.5 0.632 HDGF/ENSG00000143321.14 0.63 MOB4/ENSG00000270757.1 0.63 KLF6/ENSG00000067082.10 0.63 SMIM4/ENSG00000168273.3 0.629 ATRAID/ENSG00000138085.11 0.628 MSN/ENSG00000147065.11 0.628 RP11-112J1.1/ENSG00000213598.3 0.627 AIF1L/ENSG00000126878.8 0.625 RP11-867G2.6/ENSG00000255666.1 0.624 CRABP1/ENSG00000166426.7 0.624 NAGK/ENSG00000124357.7 0.623 ZCCHC11/ENSG00000134744.9 0.62 ZDHHC2/ENSG00000104219.8 0.619 PPP1R3B/ENSG00000173281.4 0.619 AC130352.1/ENSG00000205873.2 0.615 RP11-494M8.4/ENSG00000254951.2 0.614 ADD3/ENSG00000148700.9 0.614 RP5-1085F17.3/ENSG00000260257.1 0.613 RPN1/ENSG00000163902.7 0.613 WDR54/ENSG00000005448.12 0.612 PPM1K/ENSG00000163644.9 0.609 CCDC81/ENSG00000149201.5 0.609 ARL4D/ENSG00000175906.4 0.609 RP11-56G10.2/ENSG00000257386.1 0.608 ZNF260/ENSG00000254004.2 0.606 FIS1/ENSG00000214253.4 0.604 EMB/ENSG00000170571.7 0.601 NUDT1/ENSG00000106268.11 0.601 STMN2/ENSG00000104435.9 0.599 VPS35/ENSG00000069329.11 0.598 RP11-15H20.5/ENSG00000269837.1 0.596 SH3RF1/ENSG00000154447.10 0.596 FUOM/ENSG00000148803.7 0.594 CTSL1/ENSG00000135047.10 0.594 RP11-580I16.2/ENSG00000263766.1 0.594 MRPS18A/ENSG00000096080.7 0.593 JUP/ENSG00000173801.12 0.589 CDC42/ENSG00000070831.11 0.588 TRIM28/ENSG00000130726.7 0.587 RP11-386G11.10/ENSG00000258017.1 0.583 GPX8/ENSG00000164294.9 0.583 AKAP9/ENSG00000127914.12 0.578 CLTA/ENSG00000122705.12 0.575 MCF2L2/ENSG00000053524.7 0.575 UPP1/ENSG00000183696.9 0.575 NMRK1/ENSG00000106733.16 0.574 COL4A3BP/ENSG00000113163.11 0.573 CCDC53/ENSG00000120860.6 0.573 RAD21/ENSG00000164754.8 0.572 COL4A3/ENSG00000169031.14 0.571 TMEM179B/ENSG00000185475.4 0.571 RP11-789C1.1/ENSG00000250266.1 0.57 PARP6/ENSG00000137817.12 0.569 ITGA5/ENSG00000161638.6 0.569 SPTBN1/ENSG00000115306.11 0.569 REEP5/ENSG00000129625.8 0.567 S100PBP/ENSG00000116497.13 0.566 USP11/ENSG00000102226.4 0.566 RAB34/ENSG00000109113.13 0.565 SEMA3A/ENSG00000075213.5 0.561 FAM84B/ENSG00000168672.3 0.561 RHOC/ENSG00000155366.11 0.56 PLXNA2/ENSG00000076356.6 0.56 CTC-260E6.2/ENSG00000224864.3 0.559 OPTN/ENSG00000123240.12 0.557 TAF9B/ENSG00000187325.4 0.556 PGM1/ENSG00000079739.11 0.555 PAPSS1/ENSG00000138801.4 0.552 RP11-1085N6.6/ENSG00000270163.1 0.551 OCLN/ENSG00000197822.6 0.549 AC002480.4/ENSG00000232949.1 0.549 TPRG1L/ENSG00000158109.10 0.545 LAMTOR2/ENSG00000116586.7 0.545 RP11-638I2.10/ENSG00000258581.2 0.541 RP11-718G2.3/ENSG00000258644.1 0.538 PPP2CB/ENSG00000104695.8 0.536 DCTN1/ENSG00000204843.8 0.534 AIDA/ENSG00000186063.8 0.533 FAM104B/ENSG00000182518.9 0.531 ANK2/ENSG00000145362.12 0.53 TIPRL/ENSG00000143155.8 0.53 EPSTI1/ENSG00000133106.10 0.528 RAB5A/ENSG00000144566.6 0.528 ACAP2/ENSG00000114331.8 0.528 NRP2/ENSG00000118257.12 0.528 COA5/ENSG00000183513.4 0.527 AC068490.2/ENSG00000231200.1 0.525 CCPG1/ENSG00000260916.1 0.523 NDUFB10/ENSG00000140990.10 0.523 DUSP10/ENSG00000143507.13 0.522 LINC00371/ENSG00000226792.2 0.518 CCL2/ENSG00000108691.4 0.518 EFCAB11/ENSG00000140025.11 0.517 AC093673.5/ENSG00000232533.1 0.517 VIM/ENSG00000026025.9 0.517 CBS/ENSG00000160200.13 0.516 TUBB2B/ENSG00000137285.9 0.516 PPFIBP1/ENSG00000110841.9 0.514 PCDH7/ENSG00000169851.11 0.514 PNPLA3/ENSG00000100344.6 0.512 TNC/ENSG00000041982.10 0.512 FAM214A/ENSG00000047346.8 0.51 HIST1H2BK/ENSG00000197903.6 0.509 S100A16/ENSG00000188643.6 0.509 CRABP2/ENSG00000143320.4 0.508 TMEM135/ENSG00000166575.12 0.508 ZIC3/ENSG00000156925.7 0.507 ROR2/ENSG00000169071.10 0.507 ACLY/ENSG00000131473.12 0.506 ANP32A/ENSG00000140350.11 0.506 CEP170/ENSG00000143702.11 0.505 RNF213/ENSG00000173821.15 0.504 RBMS1/ENSG00000153250.13 0.502 B9D1/ENSG00000108641.10 0.502 FLRT3/ENSG00000125848.9 0.502 ACTR3/ENSG00000115091.7 0.501 AC002055.4/ENSG00000184319.11 0.501 RAB2A/ENSG00000104388.10 0.5 PDCD10/ENSG00000114209.10 0.499 FBLN1/ENSG00000077942.13 0.498 GABRB3/ENSG00000166206.8 0.498 B4GALT4/ENSG00000121578.8 0.497 MRPL47/ENSG00000136522.9 0.496 ATXN7L3B/ENSG00000253719.2 0.495 PAFAH1B1/ENSG00000007168.7 0.491 RP11-380D23.2/ENSG00000250103.1 0.49 CISD1/ENSG00000122873.7 0.489 ENO2/ENSG00000111674.3 0.488 WDR44/ENSG00000131725.9 0.488 ALAD/ENSG00000148218.11 0.487 CD9/ENSG00000010278.7 0.486 MYO1B/ENSG00000128641.13 0.485 WWC2/ENSG00000151718.11 0.484 POLR2I/ENSG00000105258.4 0.48 NEBL/ENSG00000078114.14 0.478 DCAF5/ENSG00000139990.13 0.477 UBAP2/ENSG00000137073.16 0.477 GGA2/ENSG00000103365.11 0.477 ASB5/ENSG00000164122.4 0.476 HERPUD1/ENSG00000051108.10 0.474 NT5DC3/ENSG00000111696.7 0.473 61E3.4/ENSG00000185864.12 0.473 DOCK1/ENSG00000150760.8 0.472 SLC50A1/ENSG00000169241.12 0.469 HAT1/ENSG00000128708.8 0.469 PABPN1/ENSG00000100836.6 0.469 LINC00467/ENSG00000153363.8 0.468 GATA6/ENSG00000141448.4 0.468 BLOC1S1/ENSG00000135441.3 0.465 EXOSC6/ENSG00000223496.1 0.465 CTD-2301A4.3/ENSG00000240729.1 0.464 LARP1B/ENSG00000138709.13 0.463 GCSH/ENSG00000140905.5 0.463 RP11-72I8.1/ENSG00000260735.1 0.463 CLPP/ENSG00000125656.4 0.463 FANCL/ENSG00000115392.7 0.463 MRPL28/ENSG00000086504.11 0.461 TCN2/ENSG00000185339.4 0.458 ABCC4/ENSG00000125257.9 0.455 PTPN12/ENSG00000127947.11 0.455 SEMA5A/ENSG00000112902.7 0.454 FLOT2/ENSG00000132589.11 0.453 DNAJB11/ENSG00000090520.6 0.452 CYP51A1/ENSG00000001630.11 0.452 TTN/ENSG00000155657.19 0.451 WDR45/ENSG00000196998.10 0.451 RIMS2/ENSG00000176406.16 0.451 LINC00665/ENSG00000232677.2 0.45 RP11-346D14.1/ENSG00000259380.1 0.45 HYOU1/ENSG00000149428.14 0.45 SERAC1/ENSG00000122335.8 0.449 RPL28/ENSG00000108107.8 0.449 CDK16/ENSG00000102225.11 0.449 ELMO1/ENSG00000155849.11 0.449 PIGP/ENSG00000185808.8 0.448 FLII/ENSG00000177731.11 0.448 CCNDBP1/ENSG00000166946.9 0.447 MLLT10/ENSG00000078403.12 0.446 RP11-139K1.2/ENSG00000227560.1 0.445 AC005682.5/ENSG00000228649.3 0.445 LUZP6/ENSG00000267697.1 0.445 COL4A6/ENSG00000197565.11 0.444 HSPA4/ENSG00000170606.9 0.443 CRTAP/ENSG00000170275.9 0.443 ZNF93/ENSG00000184635.9 0.443 ACVR2B/ENSG00000114739.8 0.443 NUAK1/ENSG00000074590.9 0.442 GLCE/ENSG00000138604.5 0.441 AP3D1/ENSG00000065000.11 0.441 SACM1L/ENSG00000211456.6 0.44 CAPZB/ENSG00000077549.13 0.44 PLOD2/ENSG00000152952.7 0.44 STARD4/ENSG00000164211.8 0.44 CLMP/ENSG00000166250.7 0.439 PLEKHB2/ENSG00000115762.12 0.439 DNMT3B/ENSG00000088305.13 0.439 RP11-90D4.2/ENSG00000226091.3 0.438 AC119673.1/ENSG00000268313.1 0.437 PELI1/ENSG00000197329.6 0.436 IDI1/ENSG00000067064.6 0.436 RBBP4/ENSG00000162521.13 0.434 ARF5/ENSG00000004059.6 0.431 PEPD/ENSG00000124299.8 0.43 S1PR3/ENSG00000213694.3 0.429 BOLA3/ENSG00000163170.7 0.429 TCP11L1/ENSG00000176148.11 0.429 ATP6V0A2/ENSG00000185344.8 0.428 RNF216/ENSG00000011275.14 0.428 P4HA1/ENSG00000122884.8 0.426 HUWE1/ENSG00000086758.11 0.424 GPR37/ENSG00000170775.2 0.423 AP2B1/ENSG00000006125.12 0.423 ITM2A/ENSG00000078596.6 0.423 IGF1R/ENSG00000140443.9 0.422 UBBP5/ENSG00000228074.1 0.422 NINL/ENSG00000101004.10 0.421 SMAGP/ENSG00000170545.12 0.42 CAP2/ENSG00000112186.7 0.42 ALDOC/ENSG00000109107.9 0.419 ASS1/ENSG00000130707.13 0.419 FAM122C/ENSG00000156500.10 0.418 CDC16/ENSG00000130177.10 0.418 BAZ2A/ENSG00000076108.7 0.417 ARHGEF10/ENSG00000104728.11 0.416 STC1/ENSG00000159167.7 0.415 EPHA4/ENSG00000116106.7 0.415 PMAIP1/ENSG00000141682.11 0.413 PRMT2/ENSG00000160310.12 0.412 TP53BP1/ENSG00000067369.9 0.412 APOBEC3G/ENSG00000239713.3 0.41 SLC4A8/ENSG00000050438.12 0.409 HTATIP2/ENSG00000109854.9 0.409 DUSP6/ENSG00000139318.7 0.408 PCDH10/ENSG00000138650.6 0.407 APOBEC3C/ENSG00000244509.2 0.407 BBS4/ENSG00000140463.9 0.407 RP11-665C16.1/ENSG00000239686.1 0.407 AP3S1/ENSG00000177879.10 0.405 MAP4K4/ENSG00000071054.11 0.405 TUBB6/ENSG00000176014.8 0.404 GLS/ENSG00000115419.8 0.404 CLINT1/ENSG00000113282.9 0.404 MAPK10/ENSG00000109339.14 0.404 GRB10/ENSG00000106070.13 0.404 RMDN1/ENSG00000176623.7 0.403 RP11-87C12.2/ENSG00000256950.1 0.402 RAB7A/ENSG00000075785.8 0.402 RNF10/ENSG00000022840.11 0.402 IWS1/ENSG00000163166.9 0.401 RNF8/ENSG00000112130.12 0.4 ZYX/ENSG00000159840.11 0.399 GPR108/ENSG00000125734.9 0.399 HNRNPH2/ENSG00000126945.8 0.399 GPM6A/ENSG00000150625.12 0.397 ACTN1/ENSG00000072110.9 0.397 STYXL1/ENSG00000127952.12 0.396 SNHG5/ENSG00000203875.5 0.394 RRAGC/ENSG00000116954.7 0.394 RCAN3/ENSG00000117602.6 0.393 TMEM45A/ENSG00000181458.6 0.392 TDRD7/ENSG00000196116.6 0.391 KDM5B/ENSG00000117139.12 0.391 CTD-2058B24.2/ENSG00000259048.1 0.39 SEMA6D/ENSG00000137872.11 0.389 TFAP2C/ENSG00000087510.5 0.387 COPG1/ENSG00000181789.10 0.385 ATG13/ENSG00000175224.12 0.385 RP11-15H20.6/ENSG00000213971.3 0.384 FAM45A/ENSG00000119979.11 0.383 OAZ2/ENSG00000180304.9 0.382 SLITRK2/ENSG00000185985.7 0.382 RGS5/ENSG00000143248.7 0.382 MDM4/ENSG00000198625.8 0.381 BLVRB/ENSG00000090013.5 0.381 LRRC48/ENSG00000171962.13 0.381 ZNF614/ENSG00000142556.14 0.38 SQLE/ENSG00000104549.7 0.38 RHPN2/ENSG00000131941.3 0.379 CREBBP/ENSG00000005339.8 0.378 NDRG4/ENSG00000103034.10 0.378 HLTF/ENSG00000071794.11 0.377 CAPG/ENSG00000042493.11 0.376 PLIN3/ENSG00000105355.4 0.375 SMAD2/ENSG00000175387.11 0.374 FAM210A/ENSG00000177150.8 0.373 CTD-2562J17.7/ENSG00000254429.1 0.373 VEGFB/ENSG00000173511.5 0.373 ERRFI1/ENSG00000116285.8 0.373 C1ORF54/ENSG00000118292.4 0.372 VANGL1/ENSG00000173218.9 0.372 ARHGAP42/ENSG00000165895.13 0.372 LHFPL2/ENSG00000145685.9 0.372 CA14/ENSG00000118298.5 0.371 SWAP70/ENSG00000133789.10 0.37 DZANK1/ENSG00000089091.11 0.368 MYH10/ENSG00000133026.8 0.368 TANGO6/ENSG00000103047.3 0.367 HHEX/ENSG00000152804.6 0.367 METTL5/ENSG00000138382.9 0.365 HSPB1/ENSG00000106211.8 0.365 RP11-123C21.2/ENSG00000270986.1 0.365 RCOR3/ENSG00000117625.9 0.364 PLCD1/ENSG00000187091.9 0.364 COX14/ENSG00000178449.3 0.364 PDLIM2/ENSG00000120913.19 0.364 ANO10/ENSG00000160746.8 0.364 NTN4/ENSG00000074527.7 0.363 TRIM36-IT1/ENSG00000250472.1 0.362 COL4A1/ENSG00000187498.10 0.361 SERPINI1/ENSG00000163536.8 0.361 OR5E1P/ENSG00000170688.3 0.36 AC007362.1/ENSG00000180672.4 0.36 NUDT19/ENSG00000213965.3 0.359 STEAP1B/ENSG00000105889.10 0.359 HSD17B14/ENSG00000087076.4 0.358 SPRY2/ENSG00000136158.6 0.357 NFASC/ENSG00000163531.11 0.356 PLTP/ENSG00000100979.10 0.355 LARP7/ENSG00000174720.11 0.354 DCAF8/ENSG00000132716.12 0.354 DDX42/ENSG00000198231.7 0.354 CDK5RAP2/ENSG00000136861.13 0.353 PYCR1/ENSG00000183010.12 0.352 CRMP1/ENSG00000072832.10 0.352 PIK3CB/ENSG00000051382.4 0.352 BEX1/ENSG00000133169.5 0.352 LRIG1/ENSG00000144749.9 0.352 ETS2/ENSG00000157557.7 0.35 SHISA3/ENSG00000178343.4 0.35 MTA3/ENSG00000057935.9 0.35 PRKAR1A/ENSG00000108946.8 0.35 TPM4/ENSG00000167460.10 0.349 USP24/ENSG00000162402.8 0.349 PPCDC/ENSG00000138621.7 0.348 MRPS23/ENSG00000181610.8 0.348 RP11-97O12.2/ENSG00000249487.2 0.348 LINC00340/ENSG00000238274.2 0.347 HBP1/ENSG00000105856.8 0.347 VASP/ENSG00000125753.9 0.346 FAM177A1/ENSG00000151327.8 0.345 KIF13B/ENSG00000197892.8 0.345 PHF5A/ENSG00000100410.3 0.344 HS6ST1/ENSG00000136720.6 0.344 RP11-235G24.2/ENSG00000220913.1 0.343 MYADM/ENSG00000179820.11 0.343 TUBB3/ENSG00000258947.2 0.342 PKP2/ENSG00000057294.9 0.341 NPY1R/ENSG00000164128.2 0.341 CTB-179K24.3/ENSG00000267176.1 0.34 CCSER2/ENSG00000107771.11 0.34 MYL12A/ENSG00000101608.6 0.34 WIBG/ENSG00000170473.12 0.339 YBX3/ENSG00000060138.8 0.338 CAMK2D/ENSG00000145349.12 0.338 JAZF1/ENSG00000153814.7 0.338 PDCL3/ENSG00000115539.9 0.337 ZNF138/ENSG00000197008.5 0.337 STT3B/ENSG00000163527.5 0.337 NCR1/ENSG00000189430.8 0.336 HMGB1P21/ENSG00000248909.1 0.336 FANCA/ENSG00000187741.9 0.336 CPNE8/ENSG00000139117.9 0.336 PKIG/ENSG00000168734.9 0.336 PAQR5/ENSG00000137819.9 0.334 UST/ENSG00000111962.7 0.333 GPATCH11/ENSG00000152133.9 0.333 RP11-1144P22.1/ENSG00000254277.1 0.332 SEPT6/ENSG00000125354.18 0.332 RPS2P5/ENSG00000240342.2 0.331 PIFO/ENSG00000173947.9 0.331 LRRN1/ENSG00000175928.5 0.331 YIF1B/ENSG00000167645.12 0.33 RP11-643A5.2/ENSG00000259669.1 0.33 ALG14/ENSG00000172339.7 0.329 PAICS/ENSG00000128050.4 0.327 CTBP2P4/ENSG00000251102.1 0.327 RPA3/ENSG00000106399.7 0.327 SERPINF1/ENSG00000132386.6 0.327 GRPR/ENSG00000126010.5 0.326 TRIM36/ENSG00000152503.5 0.325 CNN3/ENSG00000117519.11 0.325 BCAR3/ENSG00000137936.12 0.323 BBS7/ENSG00000138686.5 0.323 REST/ENSG00000084093.11 0.323 PDK1/ENSG00000152256.8 0.322 COPE/ENSG00000105669.8 0.322 IGDCC4/ENSG00000103742.7 0.322 RP11-805J14.5/ENSG00000254721.1 0.32 SPAG9/ENSG00000008294.16 0.318 ANXA11/ENSG00000122359.13 0.317 SCGB3A2/ENSG00000164265.4 0.316 NDUFB1/ENSG00000183648.4 0.316 EHHADH/ENSG00000113790.6 0.316 TIMP1/ENSG00000102265.7 0.316 DEC1/ENSG00000173077.10 0.316 RP11-474J18.2/ENSG00000249990.1 0.315 FAM154B/ENSG00000188659.5 0.315 LDHAP4/ENSG00000214110.3 0.314 CENPN/ENSG00000166451.9 0.314 GATA4/ENSG00000136574.13 0.314 MED28/ENSG00000118579.6 0.312 USP53/ENSG00000145390.7 0.311 ADCY2/ENSG00000078295.11 0.311 PDLIM7/ENSG00000196923.9 0.311 IARS/ENSG00000196305.13 0.311 CLVS2/ENSG00000146352.7 0.311 PTPN9/ENSG00000169410.5 0.31 MTUS1/ENSG00000129422.9 0.31 SEPT10/ENSG00000186522.10 0.309 APC/ENSG00000134982.12 0.309 DHCR7/ENSG00000172893.11 0.309 PTPRM/ENSG00000173482.12 0.308 ZNF518B/ENSG00000178163.3 0.308 CHEK2/ENSG00000183765.16 0.307 RAP1GDS1/ENSG00000138698.9 0.307 HCFC1R1/ENSG00000103145.6 0.307 CYB5R2/ENSG00000166394.10 0.306 RP11-69I8.2/ENSG00000236673.1 0.306 LONRF1/ENSG00000154359.8 0.306 PLCG2/ENSG00000197943.5 0.306 TMEM150C/ENSG00000249242.2 0.305 TNNT1/ENSG00000105048.12 0.305 RPL39L/ENSG00000163923.5 0.305 OR52A1/ENSG00000182070.4 0.305 SHC1/ENSG00000160691.13 0.304 DYNC2H1/ENSG00000187240.9 0.304 SERHL2/ENSG00000183569.13 0.303 FBXO25/ENSG00000147364.12 0.302 RPL32P29/ENSG00000244270.1 0.302 TMEM256P2/ENSG00000226726.1 0.301 SLC35A3/ENSG00000117620.8 0.301 KIAA1467/ENSG00000084444.9 0.301 NARS/ENSG00000134440.7 0.3 TRIP10/ENSG00000125733.13 0.3 TRAF5/ENSG00000082512.10 0.3 GAL/ENSG00000069482.6 0.299 POLE4/ENSG00000115350.7 0.298 CYP11A1/ENSG00000140459.13 0.298 RP11-148B6.2/ENSG00000250046.3 0.298 NSF/ENSG00000073969.14 0.297 LINC00504/ENSG00000248360.2 0.297 EMC9/ENSG00000100908.9 0.297 ZNF649/ENSG00000198093.6 0.296 RNASEH2A/ENSG00000104889.4 0.296 FAM85B/ENSG00000253893.2 0.296 RP11-37B2.1/ENSG00000251136.3 0.295 CCDC127/ENSG00000164366.2 0.295 ARL8B/ENSG00000134108.8 0.294 FTSJ3/ENSG00000108592.11 0.293 MYEOV2/ENSG00000172428.5 0.293 C9ORF135/ENSG00000204711.4 0.292 ATF2/ENSG00000115966.12 0.291 PCBP1/ENSG00000169564.5 0.291 TMEM63A/ENSG00000196187.7 0.29 FKBP9/ENSG00000122642.6 0.29 FBXO34/ENSG00000178974.5 0.289 LARP1/ENSG00000155506.12 0.289 TYRO3/ENSG00000092445.7 0.288 SORCS1/ENSG00000108018.11 0.288 CTC-210G5.1/ENSG00000250328.1 0.287 EXD2/ENSG00000081177.14 0.287 UBE2Q1/ENSG00000160714.5 0.287 LINC00261/ENSG00000259974.1 0.286 UROD/ENSG00000126088.8 0.284 CDR1/ENSG00000184258.5 0.283 CRNDE/ENSG00000245694.4 0.283 NDUFA7/ENSG00000267855.1 0.283 MRPL32/ENSG00000106591.3 0.282 TAL2/ENSG00000186051.4 0.281 MGMT/ENSG00000170430.9 0.281 WNT3/ENSG00000108379.5 0.281 CTD-2058B24.3/ENSG00000258696.1 0.28 GSTO2/ENSG00000065621.9 0.279 DENND2C/ENSG00000175984.10 0.278 PDIA5/ENSG00000065485.13 0.278 MBOAT1/ENSG00000172197.9 0.277 SPTAN1/ENSG00000197694.9 0.277 ARL1/ENSG00000120805.9 0.276 XIAP/ENSG00000101966.8 0.276 RALB/ENSG00000144118.9 0.275 ZNF702P/ENSG00000242779.2 0.275 SLC39A8/ENSG00000138821.8 0.275 OIP5-AS1/ENSG00000247556.2 0.274 SLC36A2/ENSG00000186335.4 0.274 SMAP1/ENSG00000112305.10 0.273 ROR1/ENSG00000185483.7 0.272 SH3KBP1/ENSG00000147010.13 0.272 CLDN6/ENSG00000184697.6 0.272 FNDC3B/ENSG00000075420.8 0.271 AXL/ENSG00000167601.7 0.27 GNPDA1/ENSG00000113552.11 0.27 ZNF75A/ENSG00000262554.1 0.268 UBA1/ENSG00000130985.12 0.268 ZFR2/ENSG00000105278.6 0.268 LMCD1/ENSG00000071282.7 0.266 NFU1/ENSG00000169599.8 0.266 RAB3B/ENSG00000169213.6 0.266 SP1/ENSG00000185591.5 0.266 RP11-10A14.6/ENSG00000253252.2 0.265 GFPT2/ENSG00000131459.8 0.265 ZNF114/ENSG00000178150.4 0.265 SSR1/ENSG00000124783.8 0.264 AFF1/ENSG00000172493.16 0.264 HESX1/ENSG00000163666.4 0.264 HMGB3/ENSG00000029993.10 0.263 TARS/ENSG00000113407.9 0.262 MINOS1/ENSG00000173436.9 0.262 IGBP1/ENSG00000089289.11 0.261 ZFAND2A/ENSG00000178381.7 0.261 RP1-288L1.4/ENSG00000237316.1 0.261 CERS4/ENSG00000090661.7 0.259 UNC45A/ENSG00000140553.12 0.259 RGS16/ENSG00000143333.6 0.259 PWWP2A/ENSG00000170234.8 0.257 REC8/ENSG00000100918.8 0.256 NEK2/ENSG00000117650.8 0.256 USP2/ENSG00000036672.11 0.256 CDK6/ENSG00000105810.5 0.256 OSTF1/ENSG00000134996.11 0.255 ZNF134/ENSG00000213762.6 0.255 ALPL/ENSG00000162551.9 0.254 GMPPB/ENSG00000173540.8 0.254 AC026806.2/ENSG00000268913.1 0.254 RP11-771K4.1/ENSG00000256232.1 0.254 NSD1/ENSG00000165671.14 0.254 ST6GAL2/ENSG00000144057.11 0.252 VIMP/ENSG00000131871.10 0.252 EIF4B/ENSG00000063046.13 0.251 GMEB1/ENSG00000162419.8 0.25 ACSL1/ENSG00000151726.9 Overrepresented GO terms in EP #5: Term Pvalue cytoskeleton organization 1.18E-06 response to topologically incorrect protein 6.60E-05 cellular component morphogenesis 8.58E-05 morphogenesis of an epithelium 9.57E-05 developmental growth involved in morphogenesis 0.000100885 cellular response to unfolded protein 0.000119933 actin filament-based process 0.000206255 tissue development 0.000371207 pyridine-containing compound metabolic process 0.000504599 heart development 0.000543363 reproductive structure development 0.000560318 positive regulation of cellular process 0.000642147 developmental cell growth 0.000684849 biological adhesion 0.000735915 oxidation-reduction process 0.000742986 nicotinamide nucleotide metabolic process 0.000819175 cell-cell adhesion 0.000834176 vasculature development 0.00087727 regulation of cell morphogenesis 0.000918203 movement of cell or subcellular component 0.000941585 cellular response to endogenous stimulus 0.001016286 cell morphogenesis involved in differentiation 0.001133088 response to chemical 0.001186621 actomyosin structure organization 0.001234149 embryo development 0.001408628 cellular response to stress 0.001542116 NADH metabolic process 0.001549171 negative regulation of cellular process 0.001673328 single-organism biosynthetic process 0.001821201 regulation of cellular component size 0.001916801 regulation of multicellular organismal development 0.002002156 response to endoplasmic reticulum stress 0.002320857 phosphorus metabolic process 0.002504377 protein complex subunit organization 0.002557143 single-organism metabolic process 0.002560953 IRE1-mediated unfolded protein response 0.002617893 regulation of cellular protein metabolic process 0.002670799 positive regulation of metabolic process 0.002777772 regulation of cell motility 0.003163124 oxidoreduction coenzyme metabolic process 0.003251325 growth 0.003342821 cellular component organization or biogenesis 0.003402255 regulation of catalytic activity 0.003410487 response to hormone 0.003568708 cell junction organization 0.003760438 programmed cell death 0.003978181 platelet degranulation 0.004950205 endoderm development 0.005444996 localization of cell 0.005679856 single organism signaling 0.005803946 cell communication 0.006286333 negative regulation of actin filament polymerization 0.006393284 regulation of protein complex disassembly 0.006492042 negative regulation of cellular component movement 0.006738525 regulation of extent of cell growth 0.007214188 circulatory system development 0.007309328 cellular response to organic substance 0.007491557 regulation of protein serine/threonine kinase activity 0.008142641 negative regulation of response to stimulus 0.008210343 enzyme linked receptor protein signaling pathway 0.008399137 organic acid metabolic process 0.008850529 actin filament organization 0.009096732 regulation of epithelial cell migration 0.009236878 blood vessel morphogenesis 0.009245717 single-organism organelle organization 0.009451216 male gonad development 0.009456516 single-organism catabolic process 0.009657008 cellular response to growth factor stimulus 0.009754619 regulation of peptidase activity 0.009763972 cellular response to glucocorticoid stimulus 0.00983455 establishment of protein localization to plasma membrane 0.010170347 negative regulation of cell proliferation 0.010228515 PERK-mediated unfolded protein response 0.01027863 regulation of cell death 0.010418052 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 0.011137352 regulation of apoptotic process 0.011675703 negative regulation of viral genome replication 0.011704523 negative regulation of protein depolymerization 0.012065563 positive regulation of cholesterol esterification 0.012136471 positive regulation of collateral sprouting 0.012136471 positive regulation of ryanodine-sensitive calcium-release channel activity 0.012136471 cellular protein complex disassembly 0.014425816 negative regulation of locomotion 0.014514609 L-serine biosynthetic process 0.016091999 positive regulation of mesoderm development 0.016091999 regulation of actin filament depolymerization 0.016329101 anatomical structure formation involved in morphogenesis 0.016386783 actin-mediated cell contraction 0.016445429 establishment of planar polarity 0.016905656 gastrulation 0.017348491 positive regulation of multicellular organismal process 0.017393302 single organism reproductive process 0.018473429 regulation of cell-substrate adhesion 0.018704058 generation of precursor metabolites and energy 0.019495122 cellular response to stimulus 0.019852778 response to corticosteroid 0.020177545 male sex differentiation 0.020177545 multi-organism process 0.020178478 regulation of axonogenesis 0.020330254 actin filament bundle assembly 0.02035232 "Wnt signaling pathway, planar cell polarity pathway " 0.020658212 positive regulation of protein metabolic process 0.020857076 macromolecular complex disassembly 0.020888902 regulation of cell communication by electrical coupling involved in cardiac conduction 0.021002333 vesicle-mediated transport 0.021446203 ribonucleoside metabolic process 0.021588714 positive regulation of substrate adhesion-dependent cell spreading 0.021768717 regulation of phosphate metabolic process 0.021871918 regulation of protein phosphorylation 0.022603118 response to oxygen-containing compound 0.023066507 positive regulation of molecular function 0.023733755 monosaccharide biosynthetic process 0.024132615 cellular response to ketone 0.024529073 regulation of actin cytoskeleton organization 0.025760885 hexose catabolic process 0.025993325 protein complex biogenesis 0.027414555 Wnt signaling pathway 0.028300627 nucleobase-containing small molecule metabolic process 0.028969587 regulation of actin filament-based process 0.029159986 organ growth 0.029860476 negative regulation of protein complex assembly 0.030170671 endodermal cell differentiation 0.030174956 cell communication by electrical coupling 0.030196404 regulation of developmental growth 0.030371128 regulation of cysteine-type endopeptidase activity 0.032375805 axis specification 0.033344697 pyrimidine ribonucleoside catabolic process 0.033654917 negative regulation of ryanodine-sensitive calcium-release channel activity 0.033654917 primitive streak formation 0.033654917 phosphorylation 0.033879812 regulation of angiogenesis 0.034095763 negative regulation of cell development 0.034839486 negative regulation of endopeptidase activity 0.036743246 cell-cell junction assembly 0.037000191 vascular endothelial growth factor receptor signaling pathway 0.037000191 pyruvate metabolic process 0.037118182 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.037325733 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 0.038109228 response to arsenic-containing substance 0.038109228 canonical glycolysis 0.038109228 response to extracellular stimulus 0.038279006 regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry 0.038766059 cellular component assembly 0.039074655 gluconeogenesis 0.039596736 glycosyl compound metabolic process 0.039962733 ameboidal-type cell migration 0.040452864 reproduction 0.04073185 digestive tract development 0.040762962 response to nitrogen compound 0.042145706 positive regulation of developmental process 0.042790535 regulation of signal transduction 0.043313587 negative regulation of intracellular signal transduction 0.044980883 sterol biosynthetic process 0.045656302 negative regulation of cell migration 0.047063622 glycolytic process through fructose-6-phosphate 0.047520454 membrane assembly 0.047520454 regulation of cardiac muscle cell contraction 0.047520454 MAPK cascade 0.048422981 cell communication involved in cardiac conduction 0.048438923 response to interferon-alpha 0.049622714 --------------------------------------------- "EP #6: 351 cells, 494 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.0285714285714286, St4_3_: 0.471264367816092, stage4: 0.557142857142857, St5_3_: 0.342465753424658, stage5_: 0.828125, stage6.2_: 0.865853658536585, stage6.7_: 0.763157894736842, stage6.14_: 0.925373134328358, " Top Genes: 3.049 SCGN/ENSG00000079689.9 2.829 STMN2/ENSG00000104435.9 2.401 CHGA/ENSG00000100604.8 2.383 MIR7-3HG/ENSG00000176840.7 2.079 TSPAN7/ENSG00000156298.8 1.971 BEX2/ENSG00000133134.7 1.796 CPE/ENSG00000109472.9 1.688 FDFT1/ENSG00000079459.8 1.659 UCHL1/ENSG00000154277.8 1.635 FOS/ENSG00000170345.5 1.61 RBP1/ENSG00000114115.5 1.535 QDPR/ENSG00000151552.7 1.511 BEX1/ENSG00000133169.5 1.484 NEUROD1/ENSG00000162992.3 1.481 TUBA1A/ENSG00000167552.9 1.471 APLP1/ENSG00000105290.6 1.43 IRF2BP2/ENSG00000168264.6 1.423 S100A6/ENSG00000197956.5 1.415 EGR1/ENSG00000120738.7 1.413 CADPS/ENSG00000163618.13 1.381 HMGCS1/ENSG00000112972.10 1.33 SCG2/ENSG00000171951.4 1.328 ATP6V0B/ENSG00000117410.9 1.294 ABCA5/ENSG00000154265.11 1.243 PTPRN/ENSG00000054356.8 1.238 HERPUD1/ENSG00000051108.10 1.234 IDI1/ENSG00000067064.6 1.23 SCG3/ENSG00000104112.4 1.223 TSPAN3/ENSG00000140391.10 1.213 SMIM6/ENSG00000259120.2 1.208 TUBA4A/ENSG00000127824.9 1.184 TPD52/ENSG00000076554.11 1.183 CKB/ENSG00000166165.8 1.182 RAB3B/ENSG00000169213.6 1.177 RTN4/ENSG00000115310.13 1.175 C3ORF14/ENSG00000114405.6 1.171 MSMO1/ENSG00000052802.8 1.17 TTR/ENSG00000118271.5 1.163 RHBDD2/ENSG00000005486.12 1.152 SCG5/ENSG00000166922.4 1.151 RP5-1085F17.3/ENSG00000260257.1 1.134 RP4-781K5.2/ENSG00000228830.1 1.134 FDPS/ENSG00000160752.10 1.116 ANXA7/ENSG00000138279.10 1.109 A1CF/ENSG00000148584.9 1.1 DYNLRB1/ENSG00000125971.12 1.096 KCNK16/ENSG00000095981.6 1.086 MYL6B/ENSG00000196465.5 1.065 BEX4/ENSG00000102409.9 1.065 CALCOCO2/ENSG00000136436.9 1.054 CYCS/ENSG00000172115.4 1.05 ELL2/ENSG00000118985.10 1.036 ALDH1A1/ENSG00000165092.8 1.027 SCD/ENSG00000099194.5 1.011 RUFY3/ENSG00000018189.7 1.003 QPCT/ENSG00000115828.11 0.977 POLR2I/ENSG00000105258.4 0.974 PCMT1/ENSG00000120265.12 0.971 CYP51A1/ENSG00000001630.11 0.963 EID1/ENSG00000255302.3 0.963 VKORC1/ENSG00000167397.10 0.959 FABP5/ENSG00000164687.6 0.959 DDC/ENSG00000132437.13 0.951 GNG2/ENSG00000186469.4 0.951 IMMP1L/ENSG00000148950.5 0.95 CACNA2D1/ENSG00000153956.11 0.949 MAP1B/ENSG00000131711.10 0.948 AL358333.1/ENSG00000267802.1 0.947 GSTA4/ENSG00000170899.6 0.938 DPYSL2/ENSG00000092964.11 0.927 ACLY/ENSG00000131473.12 0.925 MTSS1/ENSG00000170873.14 0.923 ATP6V1B2/ENSG00000147416.6 0.899 HTATSF1/ENSG00000102241.7 0.898 CRYBA2/ENSG00000163499.7 0.882 MAGED1/ENSG00000179222.12 0.877 CD200/ENSG00000091972.13 0.875 RTN3/ENSG00000133318.9 0.872 RP11-5A11.1/ENSG00000255105.1 0.858 SNRPN/ENSG00000128739.16 0.853 ST18/ENSG00000147488.7 0.851 PDHB/ENSG00000168291.8 0.848 RAB3D/ENSG00000105514.3 0.844 SORBS2/ENSG00000154556.13 0.831 LRRFIP1/ENSG00000124831.14 0.831 PSMC5/ENSG00000087191.8 0.827 VDAC3/ENSG00000078668.9 0.825 PTS/ENSG00000150787.3 0.822 BSCL2/ENSG00000168000.10 0.822 AC132217.4/ENSG00000240801.1 0.812 AC007192.6/ENSG00000269145.1 0.811 C22ORF42/ENSG00000205856.3 0.804 RIMS2/ENSG00000176406.16 0.8 WBSCR22/ENSG00000071462.7 0.798 REXO2/ENSG00000076043.5 0.793 ICA1/ENSG00000003147.13 0.775 RP11-16E23.4/ENSG00000259924.1 0.768 SNAP25/ENSG00000132639.8 0.764 C11ORF49/ENSG00000149179.8 0.754 CCDC28B/ENSG00000160050.10 0.75 AC140481.1/ENSG00000178162.4 0.75 ACTR10/ENSG00000131966.8 0.749 FAM96B/ENSG00000166595.7 0.741 REC8/ENSG00000100918.8 0.739 SEC61B/ENSG00000106803.5 0.734 SC5D/ENSG00000109929.5 0.732 LYRM2/ENSG00000083099.6 0.732 SEC11C/ENSG00000166562.4 0.729 DLK1/ENSG00000185559.9 0.728 NME1/ENSG00000239672.3 0.727 ATP1B1/ENSG00000143153.7 0.725 KCNJ6/ENSG00000157542.7 0.715 PDE4DIP/ENSG00000178104.14 0.714 TCTA/ENSG00000145022.4 0.712 GCH1/ENSG00000131979.14 0.71 RAB11A/ENSG00000103769.5 0.709 GNAS/ENSG00000087460.18 0.704 GCNT1/ENSG00000187210.8 0.703 TBCB/ENSG00000105254.6 0.699 PAIP2/ENSG00000120727.6 0.696 FIBP/ENSG00000172500.8 0.694 TUSC3/ENSG00000104723.16 0.692 PLCXD2/ENSG00000240891.2 0.689 ARL3/ENSG00000138175.7 0.687 SQLE/ENSG00000104549.7 0.687 MAGED2/ENSG00000102316.11 0.681 BTG2/ENSG00000159388.5 0.68 PRMT2/ENSG00000160310.12 0.68 CUTA/ENSG00000112514.10 0.677 SLC25A14/ENSG00000102078.11 0.675 PLD3/ENSG00000105223.14 0.674 MRFAP1/ENSG00000179010.10 0.671 GDAP1/ENSG00000104381.8 0.669 "SNRPN,SNURF/ENSG00000214265.6" 0.669 ERGIC3/ENSG00000125991.14 0.666 CAMTA1/ENSG00000171735.14 0.663 RABL5/ENSG00000128581.11 0.66 BACE1/ENSG00000186318.11 0.658 PTEN/ENSG00000171862.5 0.657 ENPP2/ENSG00000136960.8 0.644 PCMTD2/ENSG00000203880.6 0.644 RP11-834C11.4/ENSG00000250742.1 0.643 TTC39C/ENSG00000168234.8 0.638 SMARCA1/ENSG00000102038.10 0.633 SERPINB6/ENSG00000124570.13 0.631 RGPD5/ENSG00000015568.8 0.629 COX7B/ENSG00000131174.4 0.628 TSPAN13/ENSG00000106537.7 0.628 RP11-463J10.3/ENSG00000259007.1 0.626 FOXP1/ENSG00000114861.14 0.622 ASNS/ENSG00000070669.12 0.62 BNIP3/ENSG00000176171.7 0.613 CAMK2N1/ENSG00000162545.5 0.609 SCAMP1/ENSG00000085365.13 0.601 PAX6/ENSG00000007372.15 0.6 MACF1/ENSG00000127603.19 0.598 NUCB2/ENSG00000070081.10 0.595 UQCR11/ENSG00000127540.7 0.594 FXYD6/ENSG00000137726.11 0.591 PRUNE2/ENSG00000106772.13 0.59 GNG4/ENSG00000168243.6 0.589 SMDT1/ENSG00000183172.7 0.584 ADK/ENSG00000156110.9 0.582 TERF2IP/ENSG00000166848.4 0.58 PQBP1/ENSG00000102103.11 0.579 RGS2/ENSG00000116741.6 0.578 VIL1/ENSG00000127831.6 0.578 C14ORF132/ENSG00000227051.4 0.576 SLC25A4/ENSG00000151729.5 0.575 H2AFY/ENSG00000113648.12 0.572 GPI/ENSG00000105220.9 0.569 SCAPER/ENSG00000140386.8 0.568 PGRMC1/ENSG00000101856.8 0.567 LCOR/ENSG00000196233.7 0.567 EIF1AY/ENSG00000198692.5 0.566 ATP6V0D1/ENSG00000159720.7 0.565 IDS/ENSG00000010404.13 0.565 GAS2L3/ENSG00000139354.6 0.564 ANKS1B/ENSG00000185046.14 0.564 STXBP1/ENSG00000136854.13 0.563 RNASEK/ENSG00000219200.5 0.563 TMEM66/ENSG00000133872.9 0.559 CTD-3035D6.1/ENSG00000213315.4 0.558 SDCCAG8/ENSG00000054282.11 0.557 AC004696.2/ENSG00000166770.6 0.553 YPEL5/ENSG00000119801.8 0.552 KLF6/ENSG00000067082.10 0.55 SSBP2/ENSG00000145687.11 0.55 ACYP2/ENSG00000170634.7 0.548 FAM127B/ENSG00000203950.6 0.547 VEZT/ENSG00000028203.13 0.547 ID2/ENSG00000115738.5 0.545 CPEB4/ENSG00000113742.8 0.542 GBA2/ENSG00000070610.10 0.542 CAPZA2/ENSG00000198898.7 0.536 RAB3C/ENSG00000152932.6 0.535 GNG3/ENSG00000162188.5 0.534 ADIPOR1/ENSG00000159346.8 0.532 RP11-662M24.2/ENSG00000256725.1 0.53 RAB3IP/ENSG00000127328.17 0.527 KIAA1033/ENSG00000136051.9 0.525 MEAF6/ENSG00000163875.11 0.523 TCEB1/ENSG00000154582.12 0.523 SEC22B/ENSG00000223380.3 0.523 AL358781.1/ENSG00000176868.1 0.523 SLC4A8/ENSG00000050438.12 0.52 ARHGAP1/ENSG00000175220.7 0.52 TCTEX1D2/ENSG00000213123.5 0.519 ZKSCAN1/ENSG00000106261.12 0.518 ANKRD39/ENSG00000213337.4 0.517 NBEA/ENSG00000172915.14 0.515 AC007347.1/ENSG00000214696.3 0.513 CCDC53/ENSG00000120860.6 0.513 ALCAM/ENSG00000170017.8 0.512 KIFAP3/ENSG00000075945.8 0.509 NFU1/ENSG00000169599.8 0.509 MYEF2/ENSG00000104177.13 0.508 ACVR1C/ENSG00000123612.10 0.504 ORMDL1/ENSG00000128699.9 0.503 RP11-143K11.1/ENSG00000260248.1 0.502 DPP6/ENSG00000130226.12 0.499 SERINC1/ENSG00000111897.5 0.499 SMYD3/ENSG00000185420.14 0.499 ANKRD36B/ENSG00000196912.8 0.494 HMGCR/ENSG00000113161.11 0.494 MAPRE1/ENSG00000101367.8 0.493 SDR39U1/ENSG00000100445.12 0.492 KIF5C/ENSG00000168280.12 0.49 FAM46A/ENSG00000112773.11 0.489 FAM171B/ENSG00000144369.8 0.488 MRPS35/ENSG00000061794.8 0.488 GIPR/ENSG00000010310.4 0.488 POGLUT1/ENSG00000163389.6 0.487 KCNH6/ENSG00000173826.10 0.487 HARS/ENSG00000170445.8 0.486 USP11/ENSG00000102226.4 0.484 BEX5/ENSG00000184515.6 0.483 C16ORF45/ENSG00000166780.6 0.481 DGUOK/ENSG00000114956.15 0.48 CPNE1/ENSG00000214078.7 0.476 A1BG/ENSG00000121410.7 0.476 AHSA1/ENSG00000100591.3 0.475 GNAZ/ENSG00000128266.7 0.474 DAAM1/ENSG00000100592.11 0.473 AC040977.1/ENSG00000269871.1 0.471 SUCLA2/ENSG00000136143.9 0.469 COPS3/ENSG00000141030.8 0.469 KIF3A/ENSG00000131437.11 0.468 ATP6V0E1/ENSG00000113732.4 0.467 C15ORF48/ENSG00000166920.6 0.466 TCEAL1/ENSG00000172465.9 0.465 RP11-732M18.3/ENSG00000236537.1 0.461 COX7A2L/ENSG00000115944.9 0.46 THOC7/ENSG00000163634.7 0.46 ACAT2/ENSG00000120437.7 0.46 CTAGE5/ENSG00000150527.12 0.459 ENO2/ENSG00000111674.3 0.459 C7ORF55/ENSG00000164898.8 0.458 FGF14/ENSG00000102466.11 0.457 HECTD4/ENSG00000173064.6 0.457 C1GALT1C1/ENSG00000171155.7 0.456 POLR2K/ENSG00000147669.6 0.454 SLC9A3R1/ENSG00000109062.5 0.453 RP11-18I14.10/ENSG00000269609.1 0.451 PRR4/ENSG00000111215.6 0.451 PKIB/ENSG00000135549.8 0.451 KLHDC8B/ENSG00000185909.10 0.449 PIGP/ENSG00000185808.8 0.447 VAT1/ENSG00000108828.11 0.446 MRPL13/ENSG00000172172.3 0.442 PJA2/ENSG00000198961.5 0.441 SLC39A6/ENSG00000141424.8 0.441 CRIP2/ENSG00000182809.6 0.441 PPP1R7/ENSG00000115685.10 0.441 PCLO/ENSG00000186472.14 0.44 CISD2/ENSG00000145354.5 0.44 MAP1LC3B/ENSG00000140941.8 0.438 YIF1A/ENSG00000174851.10 0.437 "HYPK,SERF2/ENSG00000242028.1" 0.436 DCX/ENSG00000077279.12 0.436 MLLT3/ENSG00000171843.11 0.435 SNCA/ENSG00000145335.11 0.434 TCEAL2/ENSG00000184905.4 0.434 CLK1/ENSG00000013441.11 0.432 CHM/ENSG00000188419.8 0.429 FADS1/ENSG00000149485.11 0.427 CLDND1/ENSG00000080822.12 0.427 RRAGD/ENSG00000025039.9 0.425 FRMD4B/ENSG00000114541.10 0.424 MORN4/ENSG00000171160.13 0.423 BLVRA/ENSG00000106605.6 0.423 GRIA3/ENSG00000125675.13 0.421 PIPOX/ENSG00000179761.7 0.421 LINC00643/ENSG00000186369.5 0.42 CDKN1C/ENSG00000129757.8 0.42 ATP6V1G1/ENSG00000136888.6 0.417 GPBAR1/ENSG00000179921.10 0.416 AZI2/ENSG00000163512.9 0.415 TMCO3/ENSG00000150403.13 0.413 PPP1R14C/ENSG00000198729.4 0.413 AMPD2/ENSG00000116337.11 0.412 WDR6/ENSG00000178252.12 0.41 EDEM3/ENSG00000116406.14 0.407 GABRB3/ENSG00000166206.8 0.407 ATP5E/ENSG00000124172.5 0.407 COX17/ENSG00000138495.2 0.407 YIPF6/ENSG00000181704.7 0.406 ATP6V1F/ENSG00000128524.4 0.404 MXRA7/ENSG00000182534.9 0.404 C12ORF76/ENSG00000174456.9 0.404 EIF4A2/ENSG00000156976.10 0.403 GSTM3/ENSG00000134202.6 0.399 HAGH/ENSG00000063854.8 0.397 PREPL/ENSG00000138078.11 0.397 NAV3/ENSG00000067798.9 0.396 STON2/ENSG00000140022.5 0.395 CBX6/ENSG00000183741.7 0.395 RIMBP2/ENSG00000060709.9 0.395 ATP6V1A/ENSG00000114573.5 0.394 C14ORF1/ENSG00000133935.6 0.394 WRB/ENSG00000182093.9 0.394 COPS8/ENSG00000198612.6 0.392 MAP9/ENSG00000164114.14 0.392 CHGB/ENSG00000089199.5 0.39 SLC25A32/ENSG00000164933.7 0.388 AK1/ENSG00000106992.13 0.384 CCT4/ENSG00000115484.10 0.382 PDE5A/ENSG00000138735.11 0.381 DUSP10/ENSG00000143507.13 0.38 LINC00667/ENSG00000263753.1 0.379 PARP6/ENSG00000137817.12 0.378 IMPA1/ENSG00000133731.5 0.376 PNKD/ENSG00000127838.9 0.375 SPOCK3/ENSG00000196104.6 0.375 MGAT4A/ENSG00000071073.6 0.375 OAZ2/ENSG00000180304.9 0.374 JUND/ENSG00000130522.4 0.373 NKIRAS1/ENSG00000197885.6 0.372 AC005154.6/ENSG00000196295.6 0.372 KPNA6/ENSG00000025800.9 0.37 INA/ENSG00000148798.5 0.369 BUB3/ENSG00000154473.13 0.368 SNRNP27/ENSG00000124380.6 0.366 SCARB2/ENSG00000138760.4 0.364 MTERFD2/ENSG00000122085.11 0.363 PLCB4/ENSG00000101333.11 0.36 SELK/ENSG00000113811.6 0.359 PABPN1/ENSG00000100836.6 0.358 CISD1/ENSG00000122873.7 0.358 GNAI1/ENSG00000127955.11 0.357 CXXC4/ENSG00000168772.9 0.356 SLC35G2/ENSG00000168917.8 0.356 HINT2/ENSG00000137133.6 0.354 AARSD1/ENSG00000266967.2 0.354 SBDSP1/ENSG00000225648.1 0.352 CALM1/ENSG00000198668.6 0.348 ESYT1/ENSG00000139641.8 0.348 BOLA3/ENSG00000163170.7 0.347 TTLL7/ENSG00000137941.12 0.347 KIAA1324/ENSG00000116299.12 0.346 UBE2J1/ENSG00000198833.6 0.346 MAN1A1/ENSG00000111885.5 0.346 RNF8/ENSG00000112130.12 0.344 NIPSNAP1/ENSG00000184117.7 0.343 DHRS1/ENSG00000157379.9 0.343 RFX6/ENSG00000185002.5 0.343 FKBP9/ENSG00000122642.6 0.342 RIIAD1/ENSG00000178796.8 0.341 DCP1A/ENSG00000162290.11 0.341 CRMP1/ENSG00000072832.10 0.341 COL4A3BP/ENSG00000113163.11 0.341 CLASP1/ENSG00000074054.13 0.339 ABHD14A/ENSG00000248487.4 0.339 REEP1/ENSG00000068615.11 0.338 MIEN1/ENSG00000141741.7 0.337 ERC1/ENSG00000082805.14 0.337 ATP6V0A1/ENSG00000033627.10 0.337 RIC3/ENSG00000166405.10 0.336 SELT/ENSG00000198843.8 0.332 RP11-571M6.7/ENSG00000257342.1 0.331 ETNK1/ENSG00000139163.11 0.33 ASH1L/ENSG00000116539.6 0.326 C14ORF142/ENSG00000170270.4 0.326 RGS9/ENSG00000108370.11 0.326 DPY30/ENSG00000162961.9 0.326 SVIP/ENSG00000198168.4 0.325 CDK5/ENSG00000164885.8 0.325 EHBP1/ENSG00000115504.10 0.324 DDAH1/ENSG00000153904.14 0.322 NAV1/ENSG00000134369.11 0.322 FAM219B/ENSG00000178761.10 0.322 RUNDC3A/ENSG00000108309.8 0.322 STT3B/ENSG00000163527.5 0.321 RAD21/ENSG00000164754.8 0.32 ISYNA1/ENSG00000105655.12 0.319 PMM1/ENSG00000100417.7 0.318 AMACR/ENSG00000242110.3 0.318 UBR3/ENSG00000144357.12 0.317 SLC25A53/ENSG00000176274.6 0.316 DMXL2/ENSG00000104093.9 0.316 LYRM5/ENSG00000205707.5 0.315 ITGAE/ENSG00000083457.7 0.314 SMPDL3A/ENSG00000172594.8 0.314 FSD1L/ENSG00000106701.7 0.313 GLRX/ENSG00000173221.9 0.311 DNAJB9/ENSG00000128590.4 0.31 MPZL3/ENSG00000160588.5 0.308 TPPP3/ENSG00000159713.6 0.308 AC023590.1/ENSG00000225885.2 0.308 SLC25A20/ENSG00000178537.5 0.307 TMX4/ENSG00000125827.4 0.307 PTGES3/ENSG00000110958.11 0.305 KIF21A/ENSG00000139116.13 0.305 AIF1/ENSG00000204472.8 0.305 AC093673.5/ENSG00000232533.1 0.304 CPNE3/ENSG00000085719.7 0.304 PPP3CB/ENSG00000107758.11 0.303 NRXN1/ENSG00000179915.16 0.302 ZNF655/ENSG00000197343.5 0.3 SLC46A1/ENSG00000076351.8 0.299 PDRG1/ENSG00000088356.4 0.299 TMEM248/ENSG00000106609.11 0.298 PTP4A1/ENSG00000112245.6 0.297 TSNAX/ENSG00000116918.9 0.297 ANKRD36C/ENSG00000174501.10 0.296 ZNF721/ENSG00000182903.11 0.296 TCEAL4/ENSG00000133142.13 0.296 NRSN2/ENSG00000125841.7 0.296 COPG1/ENSG00000181789.10 0.295 ARL6IP5/ENSG00000144746.6 0.293 EMC9/ENSG00000100908.9 0.293 LAMB1/ENSG00000091136.9 0.293 RP11-531A24.3/ENSG00000260838.2 0.292 PTPRN2/ENSG00000155093.13 0.292 UBE2G1/ENSG00000132388.8 0.291 TXLNA/ENSG00000084652.11 0.288 PLXNA2/ENSG00000076356.6 0.287 ARF1/ENSG00000143761.9 0.287 OLA1/ENSG00000138430.11 0.286 KPNA1/ENSG00000114030.8 0.286 HOOK1/ENSG00000134709.6 0.286 SERPINB1/ENSG00000021355.8 0.284 DTNA/ENSG00000134769.17 0.284 MRP63/ENSG00000173141.4 0.284 RP11-318M2.3/ENSG00000253851.1 0.284 NOP58/ENSG00000055044.6 0.283 SYT11/ENSG00000132718.7 0.283 RP4-594I10.3/ENSG00000264443.1 0.283 PVRL3/ENSG00000177707.6 0.282 BAALC/ENSG00000164929.12 0.281 GRIA2/ENSG00000120251.14 0.28 LYST/ENSG00000143669.9 0.28 MANF/ENSG00000145050.11 0.279 RP11-513I15.6/ENSG00000225339.2 0.278 CMAS/ENSG00000111726.8 0.278 FSTL5/ENSG00000168843.9 0.277 NGRN/ENSG00000182768.7 0.275 MARS/ENSG00000166986.8 0.274 RP11-676J15.1/ENSG00000263958.1 0.273 TTC8/ENSG00000165533.14 0.273 FAM174A/ENSG00000174132.8 0.271 ITFG1/ENSG00000129636.8 0.27 MAPRE2/ENSG00000166974.8 0.27 BTBD3/ENSG00000132640.10 0.269 SGCB/ENSG00000163069.8 0.269 LDLR/ENSG00000130164.7 0.269 BPNT1/ENSG00000162813.13 0.269 SUSD4/ENSG00000143502.9 0.268 FBXO3/ENSG00000110429.9 0.267 TUBB4B/ENSG00000188229.5 0.264 PDXDC2P/ENSG00000196696.7 0.263 CLGN/ENSG00000153132.8 0.262 C1ORF210/ENSG00000253313.1 0.261 UNC13B/ENSG00000198722.8 0.261 YWHAH/ENSG00000128245.10 0.26 SLC41A2/ENSG00000136052.5 0.259 FOXO1/ENSG00000150907.6 0.257 PCSK2/ENSG00000125851.5 0.257 ARHGDIA/ENSG00000141522.7 0.256 TARS/ENSG00000113407.9 0.255 INPP1/ENSG00000151689.8 0.254 PIGK/ENSG00000142892.10 0.254 ARIH2/ENSG00000177479.15 0.254 CD47/ENSG00000196776.10 0.254 PLXNC1/ENSG00000136040.4 0.253 TMEM17/ENSG00000186889.5 0.252 RP11-393B14.1/ENSG00000240024.1 0.251 TTC39A/ENSG00000085831.11 0.251 MAST3/ENSG00000099308.5 0.251 DZIP3/ENSG00000198919.8 0.251 CSRP1/ENSG00000159176.9 0.251 AC140481.7/ENSG00000240253.1 0.251 GOT1/ENSG00000120053.9 0.25 MAPK1IP1L/ENSG00000168175.9 Overrepresented GO terms in EP #6: Term Pvalue alcohol biosynthetic process 3.29E-06 hydrogen ion transmembrane transport 8.31E-06 phagosome acidification 1.68E-05 cholesterol biosynthetic process 2.79E-05 hydrogen transport 2.80E-05 small molecule metabolic process 7.83E-05 transferrin transport 0.0001468 synaptic vesicle cycle 0.000176275 trivalent inorganic cation transport 0.000229352 synaptic vesicle transport 0.000498012 ATP hydrolysis coupled proton transport 0.00065049 pH reduction 0.000744347 vesicle-mediated transport in synapse 0.0012646 steroid biosynthetic process 0.001290595 regulation of synaptic vesicle recycling 0.001360891 response to organonitrogen compound 0.001769984 isoprenoid biosynthetic process 0.00230794 iron ion transport 0.003568587 neuron projection extension 0.003883766 regulation of high voltage-gated calcium channel activity 0.003905367 secondary alcohol metabolic process 0.003931362 regulation of macroautophagy 0.005004224 establishment of vesicle localization 0.005842339 sterol metabolic process 0.007917165 nucleoside triphosphate metabolic process 0.008129695 synaptic vesicle priming 0.00880644 neurotransmitter secretion 0.009848047 regulation of synaptic plasticity 0.010574647 monovalent inorganic cation transport 0.012795222 regulation of microtubule polymerization 0.013013387 inositol phosphate metabolic process 0.013655258 amide transport 0.014430879 methylglyoxal metabolic process 0.01445298 regulation of axon extension 0.016021279 regulation of intracellular pH 0.016021279 signal release 0.017394145 cellular monovalent inorganic cation homeostasis 0.019523789 negative regulation of microtubule polymerization or depolymerization 0.019627764 cation transmembrane transport 0.021463617 motor neuron axon guidance 0.023751531 response to peptide hormone 0.0243962 response to glucose 0.024399158 pancreatic A cell differentiation 0.024770908 tetrahydrobiopterin biosynthetic process 0.024770908 cellular chemical homeostasis 0.026082564 organelle localization 0.02649466 establishment of protein localization 0.026688347 insulin secretion 0.027140054 ER-associated ubiquitin-dependent protein catabolic process 0.027721643 ergosterol biosynthetic process 0.027790836 phytosteroid metabolic process 0.027790836 dihydrobiopterin metabolic process 0.027790836 localization 0.028036479 single-organism biosynthetic process 0.029300356 purine ribonucleotide metabolic process 0.029616701 cerebral cortex radial glia guided migration 0.029640124 purine ribonucleoside metabolic process 0.029794124 regulated exocytosis 0.030383344 cellular ion homeostasis 0.035627508 insulin receptor signaling pathway 0.037881786 relaxation of cardiac muscle 0.03791506 response to monosaccharide 0.038001362 single-organism cellular process 0.038548346 inorganic ion transmembrane transport 0.045009836 purine-containing compound metabolic process 0.046103969 positive regulation of calcium ion transmembrane transporter activity 0.046964269 positive regulation of calcium ion-dependent exocytosis 0.047686077 negative regulation of synaptic transmission 0.047786275 regulation of neurotransmitter transport 0.047786275 purine ribonucleoside triphosphate metabolic process 0.048784069 --------------------------------------------- "EP #7: 59 cells, 748 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 0.0793650793650794, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0.0136986301369863, stage5_: 0, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0, " Top Genes: 3.885 TDGF1/ENSG00000241186.3 3.845 DPPA4/ENSG00000121570.8 3.83 IFITM1/ENSG00000185885.11 3.75 RP11-148B6.1/ENSG00000249532.1 3.706 ESRG/ENSG00000265992.1 3.398 LINC00678/ENSG00000254934.1 3.347 RP11-1144P22.1/ENSG00000254277.1 3.273 IFITM3/ENSG00000142089.11 3.267 ABRACL/ENSG00000146386.7 3.247 TERF1/ENSG00000147601.9 3.199 DNMT3B/ENSG00000088305.13 3.17 L1TD1/ENSG00000240563.1 3.169 PMAIP1/ENSG00000141682.11 3.027 SKIL/ENSG00000136603.9 2.985 UGP2/ENSG00000169764.10 2.97 MGST1/ENSG00000008394.7 2.823 AASS/ENSG00000008311.10 2.624 RP11-380P13.2/ENSG00000251292.1 2.596 PIM2/ENSG00000102096.9 2.57 LITAF/ENSG00000189067.8 2.543 GJA1/ENSG00000152661.7 2.532 SNHG14/ENSG00000224078.6 2.52 MT1X/ENSG00000187193.8 2.511 SLC2A3/ENSG00000059804.11 2.507 LIN28A/ENSG00000131914.6 2.436 RP4-792G4.2/ENSG00000230798.1 2.416 CTSC/ENSG00000109861.11 2.375 RP11-267L5.1/ENSG00000254339.1 2.349 UCHL1/ENSG00000154277.8 2.244 SLC16A1/ENSG00000155380.7 2.228 CKB/ENSG00000166165.8 2.142 SCGB3A2/ENSG00000164265.4 2.129 PSIP1/ENSG00000164985.10 2.104 CD9/ENSG00000010278.7 2.094 PDLIM1/ENSG00000107438.4 2.05 DNAJB6/ENSG00000105993.10 2.04 AC005062.2/ENSG00000243004.1 2 FDFT1/ENSG00000079459.8 1.978 RPL39L/ENSG00000163923.5 1.962 MTHFD2/ENSG00000065911.7 1.925 HMGCS1/ENSG00000112972.10 1.922 USP44/ENSG00000136014.7 1.865 TSTD1/ENSG00000215845.6 1.836 PLS3/ENSG00000102024.11 1.832 SOX4/ENSG00000124766.4 1.829 RP11-132A1.3/ENSG00000232301.1 1.807 SNRPN/ENSG00000128739.16 1.788 SFRP2/ENSG00000145423.4 1.785 SPP1/ENSG00000118785.9 1.771 FABP5/ENSG00000164687.6 1.725 HHLA1/ENSG00000132297.7 1.696 PSAT1/ENSG00000135069.9 1.695 GULP1/ENSG00000144366.11 1.685 ZIC2/ENSG00000043355.6 1.683 ACAT2/ENSG00000120437.7 1.669 SPARC/ENSG00000113140.6 1.662 ANXA2/ENSG00000182718.11 1.662 PTPRZ1/ENSG00000106278.7 1.661 GGCT/ENSG00000006625.13 1.658 MAD2L2/ENSG00000116670.10 1.656 PGAM1/ENSG00000171314.8 1.647 MSMO1/ENSG00000052802.8 1.646 TOMM7/ENSG00000196683.6 1.636 PFDN4/ENSG00000101132.5 1.622 ACOT13/ENSG00000112304.5 1.621 DPYSL2/ENSG00000092964.11 1.617 PFN1/ENSG00000108518.7 1.614 RNA28S5/ENSG00000226958.1 1.605 RP11-701H24.2/ENSG00000257151.1 1.6 RP11-256I9.2/ENSG00000260834.1 1.566 HMGA1/ENSG00000137309.15 1.533 VCAN/ENSG00000038427.11 1.531 RBPMS/ENSG00000157110.11 1.528 RPL22/ENSG00000116251.5 1.515 LDB2/ENSG00000169744.8 1.496 PHGDH/ENSG00000092621.7 1.492 CXADR/ENSG00000154639.14 1.487 GLDC/ENSG00000178445.8 1.486 LAPTM4B/ENSG00000104341.12 1.483 LECT1/ENSG00000136110.8 1.473 DNMT3A/ENSG00000119772.12 1.456 CRABP1/ENSG00000166426.7 1.455 RP11-701H24.5/ENSG00000270704.1 1.451 TKT/ENSG00000163931.11 1.447 HMGN5/ENSG00000198157.6 1.426 PHC1/ENSG00000111752.5 1.42 RBPJ/ENSG00000168214.16 1.409 IDO1/ENSG00000131203.8 1.409 SALL2/ENSG00000165821.7 1.404 JMJD1C/ENSG00000171988.13 1.371 DANCR/ENSG00000226950.2 1.371 NDUFAF2/ENSG00000164182.6 1.368 CDH1/ENSG00000039068.13 1.365 PTTG1/ENSG00000164611.8 1.362 RABGAP1L/ENSG00000152061.17 1.361 SEMA6A/ENSG00000092421.12 1.36 SLC7A3/ENSG00000165349.7 1.327 CTSL2/ENSG00000136943.6 1.323 FAM162A/ENSG00000114023.11 1.319 AC074289.1/ENSG00000225889.2 1.311 RBPMS2/ENSG00000166831.4 1.308 RP11-161H23.5/ENSG00000258232.2 1.306 LDHA/ENSG00000134333.9 1.302 ATP5G1/ENSG00000159199.8 1.291 TARS/ENSG00000113407.9 1.287 CLU/ENSG00000120885.15 1.284 IDI1/ENSG00000067064.6 1.278 PRDM14/ENSG00000147596.3 1.269 CYP51A1/ENSG00000001630.11 1.269 CBR1/ENSG00000159228.8 1.267 SLC39A10/ENSG00000196950.9 1.265 TFDP2/ENSG00000114126.13 1.259 NQO1/ENSG00000181019.8 1.235 DUT/ENSG00000128951.9 1.233 PODXL/ENSG00000128567.12 1.226 MTA3/ENSG00000057935.9 1.208 RP11-108M9.4/ENSG00000238142.1 1.203 CCND2/ENSG00000118971.3 1.2 CLDN10/ENSG00000134873.5 1.179 CYCS/ENSG00000172115.4 1.178 RP11-301L7.1/ENSG00000271051.1 1.175 ASNS/ENSG00000070669.12 1.169 CSRP2/ENSG00000175183.5 1.156 CLIC4/ENSG00000169504.10 1.156 RP11-329L6.1/ENSG00000266402.1 1.156 ATP5H/ENSG00000167863.7 1.15 EIF5A/ENSG00000132507.13 1.15 DNAJA2/ENSG00000069345.7 1.149 FXYD5/ENSG00000089327.10 1.149 POMP/ENSG00000132963.7 1.141 RPA3/ENSG00000106399.7 1.137 C9ORF123/ENSG00000137038.7 1.133 CCDC169/ENSG00000242715.3 1.132 HESX1/ENSG00000163666.4 1.132 ZBTB8OS/ENSG00000176261.11 1.131 PCBP1/ENSG00000169564.5 1.13 POLR3G/ENSG00000113356.6 1.128 RP11-69I8.2/ENSG00000236673.1 1.128 ACOT7/ENSG00000097021.14 1.124 C1QBP/ENSG00000108561.4 1.123 CISD1/ENSG00000122873.7 1.123 PLA2G16/ENSG00000176485.6 1.117 YBX3/ENSG00000060138.8 1.115 B3GNT7/ENSG00000156966.6 1.112 MLF1/ENSG00000178053.13 1.111 USP28/ENSG00000048028.7 1.106 MAT2B/ENSG00000038274.11 1.104 PHACTR2/ENSG00000112419.10 1.097 NANOG/ENSG00000111704.6 1.097 DCAF13/ENSG00000164934.9 1.09 MYO10/ENSG00000145555.10 1.089 ZNF738/ENSG00000172687.9 1.087 SQLE/ENSG00000104549.7 1.079 CDCA7L/ENSG00000164649.15 1.07 RARRES2/ENSG00000106538.5 1.067 ENAH/ENSG00000154380.11 1.06 OCIAD2/ENSG00000145247.7 1.055 CALD1/ENSG00000122786.15 1.052 OAZ2/ENSG00000180304.9 1.042 METTL3/ENSG00000165819.7 1.026 ARL2/ENSG00000213465.3 1.024 RP11-366M4.3/ENSG00000248329.1 1.022 SF3B14/ENSG00000115128.6 1.018 S100A10/ENSG00000197747.4 1.017 RP11-132A1.4/ENSG00000232445.1 1.011 CTC-210G5.1/ENSG00000250328.1 1.002 RP11-701H24.8/ENSG00000270246.1 1.001 GABRB3/ENSG00000166206.8 1 LARP7/ENSG00000174720.11 0.997 AXL/ENSG00000167601.7 0.991 TUBB2B/ENSG00000137285.9 0.986 IFITM2/ENSG00000185201.12 0.982 ITM2A/ENSG00000078596.6 0.981 CNN3/ENSG00000117519.11 0.978 OIP5-AS1/ENSG00000247556.2 0.978 CEBPZ/ENSG00000115816.9 0.976 ABHD12B/ENSG00000131969.10 0.972 SC5D/ENSG00000109929.5 0.969 PIR/ENSG00000087842.6 0.968 SNHG3/ENSG00000242125.1 0.966 MSH2/ENSG00000095002.8 0.966 BOLA3/ENSG00000163170.7 0.964 SEC61G/ENSG00000132432.9 0.962 PTBP2/ENSG00000117569.13 0.958 BEX2/ENSG00000133134.7 0.956 BCAT1/ENSG00000060982.10 0.954 JPX/ENSG00000225470.2 0.951 COMMD10/ENSG00000145781.4 0.948 USP9X/ENSG00000124486.7 0.946 FAM126A/ENSG00000122591.7 0.946 CHEK2/ENSG00000183765.16 0.944 YBX1/ENSG00000065978.13 0.938 DHCR24/ENSG00000116133.7 0.936 DMKN/ENSG00000161249.16 0.934 AKIRIN1/ENSG00000174574.11 0.932 CTC-260E6.6/ENSG00000267383.2 0.931 ARL4A/ENSG00000122644.8 0.929 ZFP42/ENSG00000179059.5 0.921 ZMYND8/ENSG00000101040.15 0.921 VCAN-AS1/ENSG00000249835.2 0.918 VSIG10/ENSG00000176834.9 0.917 JARID2/ENSG00000008083.9 0.916 RP11-18I14.10/ENSG00000269609.1 0.915 POU5F1/ENSG00000204531.10 0.91 EIF4EBP1/ENSG00000187840.4 0.909 BUB1/ENSG00000169679.10 0.908 PLP1/ENSG00000123560.9 0.902 UQCRB/ENSG00000156467.5 0.901 NR6A1/ENSG00000148200.12 0.901 TCEAL8/ENSG00000180964.12 0.9 AC107016.1/ENSG00000225410.1 0.897 FBL/ENSG00000105202.3 0.89 ARID2/ENSG00000189079.11 0.89 CBS/ENSG00000160200.13 0.879 SNHG8/ENSG00000269893.1 0.877 USO1/ENSG00000138768.10 0.877 GMPS/ENSG00000163655.10 0.876 FGFR1/ENSG00000077782.15 0.874 RPL22L1/ENSG00000163584.13 0.873 COX17/ENSG00000138495.2 0.872 VAT1/ENSG00000108828.11 0.871 DDX21/ENSG00000165732.8 0.867 IQGAP1/ENSG00000140575.8 0.867 SEPHS1/ENSG00000086475.10 0.861 ITGB1/ENSG00000150093.14 0.852 TALDO1/ENSG00000177156.6 0.847 RAB34/ENSG00000109113.13 0.844 KRT18/ENSG00000111057.6 0.843 SMIM14/ENSG00000163683.6 0.837 CYP2S1/ENSG00000167600.9 0.835 PLK1S1/ENSG00000088970.11 0.834 ZFP36L1/ENSG00000185650.8 0.834 PAN3/ENSG00000152520.9 0.833 PMEL/ENSG00000185664.10 0.829 CMC1/ENSG00000187118.8 0.828 RNF10/ENSG00000022840.11 0.825 PDPN/ENSG00000162493.12 0.818 COX7B/ENSG00000131174.4 0.818 PAICS/ENSG00000128050.4 0.817 RP11-562F9.2/ENSG00000249152.1 0.817 ALDOC/ENSG00000109107.9 0.815 CENPW/ENSG00000203760.4 0.813 BST2/ENSG00000130303.8 0.812 SSBP2/ENSG00000145687.11 0.809 PHF17/ENSG00000077684.11 0.809 NDUFB1/ENSG00000183648.4 0.802 TMSB4XP8/ENSG00000187653.10 0.8 LTA4H/ENSG00000111144.5 0.799 ID1/ENSG00000125968.7 0.795 ELOVL6/ENSG00000170522.5 0.793 VSNL1/ENSG00000163032.7 0.792 VASH2/ENSG00000143494.11 0.791 RPS2/ENSG00000140988.11 0.79 SOX2/ENSG00000181449.2 0.789 RPF2/ENSG00000197498.7 0.786 VRK1/ENSG00000100749.3 0.785 PPAT/ENSG00000128059.4 0.785 TNRC6A/ENSG00000090905.13 0.785 TNNI3/ENSG00000129991.8 0.784 AC011558.5/ENSG00000267020.1 0.782 SMIM20/ENSG00000250317.4 0.78 UNG/ENSG00000076248.6 0.78 PAK1/ENSG00000149269.5 0.779 HMGN4/ENSG00000182952.4 0.776 THY1/ENSG00000154096.9 0.771 ZNF589/ENSG00000164048.9 0.77 NDUFAF4/ENSG00000123545.5 0.77 CRABP2/ENSG00000143320.4 0.769 ZMYM2/ENSG00000121741.11 0.768 CRMP1/ENSG00000072832.10 0.768 COMMD6/ENSG00000188243.8 0.762 NME4/ENSG00000103202.8 0.762 RCC2/ENSG00000179051.9 0.76 HPRT1/ENSG00000165704.10 0.758 TMX1/ENSG00000139921.8 0.757 HAUS1/ENSG00000152240.8 0.752 RP11-701H24.4/ENSG00000261069.1 0.749 AP1S2/ENSG00000182287.9 0.747 SPG20/ENSG00000133104.8 0.746 REXO2/ENSG00000076043.5 0.744 APOC1/ENSG00000130208.5 0.743 AC007390.5/ENSG00000218739.4 0.741 CA14/ENSG00000118298.5 0.74 ELOVL5/ENSG00000012660.9 0.737 LGALS1/ENSG00000100097.7 0.736 PROSER1/ENSG00000120685.14 0.736 NDUFS6/ENSG00000145494.7 0.733 TCF7L1/ENSG00000152284.4 0.73 "SNRPN,SNURF/ENSG00000214265.6" 0.73 ACLY/ENSG00000131473.12 0.729 STRBP/ENSG00000165209.14 0.729 SMIM4/ENSG00000168273.3 0.729 ATRX/ENSG00000085224.16 0.726 COQ3/ENSG00000132423.6 0.719 HRSP12/ENSG00000132541.6 0.717 BPTF/ENSG00000171634.12 0.714 COA6/ENSG00000168275.10 0.714 GYG1/ENSG00000163754.13 0.712 MIF/ENSG00000240972.1 0.711 PGRMC1/ENSG00000101856.8 0.711 CTD-2306M5.1/ENSG00000248605.1 0.71 AP002856.5/ENSG00000231698.1 0.709 ATPBD4/ENSG00000134146.7 0.706 KLHL7/ENSG00000122550.12 0.704 CXCL12/ENSG00000107562.12 0.704 ZWILCH/ENSG00000174442.7 0.701 COX20/ENSG00000203667.5 0.7 TMEM135/ENSG00000166575.12 0.7 RP11-660L16.2/ENSG00000254682.1 0.699 ALPL/ENSG00000162551.9 0.695 FGGY/ENSG00000172456.12 0.694 TMTC3/ENSG00000139324.7 0.694 HDAC1/ENSG00000116478.7 0.693 NUCKS1/ENSG00000069275.12 0.691 TRIM71/ENSG00000206557.4 0.691 MIS18A/ENSG00000159055.3 0.689 SHISA2/ENSG00000180730.4 0.688 GPN3/ENSG00000111231.3 0.684 CDKN3/ENSG00000100526.15 0.683 PPAP2A/ENSG00000067113.12 0.682 NMU/ENSG00000109255.7 0.681 PIP4K2A/ENSG00000150867.9 0.68 TNNT1/ENSG00000105048.12 0.678 SPATS2L/ENSG00000196141.7 0.676 CRYZ/ENSG00000116791.9 0.675 CETN3/ENSG00000153140.4 0.674 MAP1B/ENSG00000131711.10 0.672 RP11-469A15.2/ENSG00000230623.2 0.669 VAMP8/ENSG00000118640.6 0.669 NDUFA5/ENSG00000128609.10 0.666 CNN2/ENSG00000064666.9 0.66 HNRNPAB/ENSG00000197451.6 0.66 TAF9B/ENSG00000187325.4 0.658 HSPB1/ENSG00000106211.8 0.658 CCDC59/ENSG00000133773.7 0.657 SCD/ENSG00000099194.5 0.655 TRIM24/ENSG00000122779.12 0.654 RRAS2/ENSG00000133818.8 0.65 RSRC2/ENSG00000111011.13 0.65 CHORDC1/ENSG00000110172.7 0.65 UBE2L6/ENSG00000156587.11 0.649 RTN3/ENSG00000133318.9 0.648 TGIF1/ENSG00000177426.15 0.648 ZFP36L2/ENSG00000152518.5 0.648 LINC00263/ENSG00000235823.1 0.648 KIAA1551/ENSG00000174718.7 0.646 SCG5/ENSG00000166922.4 0.646 RP11-436H22.1/ENSG00000270348.1 0.643 ITM2C/ENSG00000135916.11 0.642 SFRP1/ENSG00000104332.7 0.639 GLS/ENSG00000115419.8 0.638 MSH6/ENSG00000116062.8 0.638 MRPL11/ENSG00000174547.9 0.633 FERMT2/ENSG00000073712.9 0.633 SSSCA1/ENSG00000173465.3 0.632 ZFYVE21/ENSG00000100711.9 0.632 CRTAP/ENSG00000170275.9 0.632 KNOP1/ENSG00000103550.9 0.627 RP11-426L16.8/ENSG00000215866.3 0.626 HMMR/ENSG00000072571.14 0.625 NMRK2/ENSG00000077009.9 0.622 CDCA7/ENSG00000144354.9 0.622 RTN4IP1/ENSG00000130347.8 0.621 RND2/ENSG00000108830.7 0.621 GRPR/ENSG00000126010.5 0.619 LSM4/ENSG00000130520.4 0.619 RP11-304L19.5/ENSG00000260260.1 0.618 RP11-122C9.1/ENSG00000137970.7 0.617 AP3S2/ENSG00000157823.12 0.614 SLC25A4/ENSG00000151729.5 0.612 YWHAH/ENSG00000128245.10 0.611 OLFML3/ENSG00000116774.7 0.61 BLVRB/ENSG00000090013.5 0.61 FAM98A/ENSG00000119812.14 0.609 EEF1E1/ENSG00000124802.7 0.608 CISD2/ENSG00000145354.5 0.607 TMSB15A/ENSG00000158164.6 0.606 RP11-46C20.1/ENSG00000250337.1 0.606 GSTO2/ENSG00000065621.9 0.606 TSC22D1/ENSG00000102804.10 0.605 RP11-265N6.1/ENSG00000261684.1 0.603 OTX2/ENSG00000165588.12 0.6 COX5A/ENSG00000178741.7 0.595 GPRC5B/ENSG00000167191.7 0.595 CYB5R2/ENSG00000166394.10 0.594 NDUFB5/ENSG00000136521.8 0.593 CDKN2AIPNL/ENSG00000237190.3 0.593 RHEB/ENSG00000106615.5 0.592 RP11-44F21.5/ENSG00000260265.1 0.591 CTD-2501M5.1/ENSG00000253507.1 0.587 FDPS/ENSG00000160752.10 0.587 LDHB/ENSG00000111716.8 0.585 GDF3/ENSG00000184344.3 0.585 "HYPK,SERF2/ENSG00000242028.1" 0.585 SKA3/ENSG00000165480.11 0.583 M6PR/ENSG00000003056.3 0.581 RMST/ENSG00000255794.2 0.579 ZIC3/ENSG00000156925.7 0.577 IFI30/ENSG00000216490.2 0.577 SLC29A1/ENSG00000112759.12 0.576 RP11-363E7.4/ENSG00000260912.1 0.575 LINC00116/ENSG00000175701.6 0.575 MAPKAPK5-AS1/ENSG00000234608.2 0.575 POP7/ENSG00000172336.4 0.572 BCL11A/ENSG00000119866.16 0.572 PLGRKT/ENSG00000107020.5 0.572 SLC1A5/ENSG00000105281.8 0.571 METTL22/ENSG00000067365.10 0.57 CHCHD1/ENSG00000172586.7 0.57 CENPN/ENSG00000166451.9 0.569 VWDE/ENSG00000146530.7 0.566 SETD5-AS1/ENSG00000206573.4 0.566 SALL4/ENSG00000101115.8 0.566 COTL1/ENSG00000103187.5 0.566 SAAL1/ENSG00000166788.5 0.563 DNAH14/ENSG00000185842.10 0.563 ZCRB1/ENSG00000139168.3 0.561 GCSH/ENSG00000140905.5 0.561 SCG3/ENSG00000104112.4 0.557 PSMG1/ENSG00000183527.7 0.556 ZNF880/ENSG00000221923.4 0.555 GPX8/ENSG00000164294.9 0.555 RP4-816N1.7/ENSG00000258092.1 0.553 NUP35/ENSG00000163002.8 0.553 LDLR/ENSG00000130164.7 0.552 TRIML2/ENSG00000179046.4 0.552 UBE2I/ENSG00000103275.14 0.551 MST4/ENSG00000134602.11 0.55 TMEM64/ENSG00000180694.9 0.548 DNAJC19/ENSG00000205981.2 0.548 CAPG/ENSG00000042493.11 0.548 AP3S1/ENSG00000177879.10 0.548 C1ORF54/ENSG00000118292.4 0.546 NFU1/ENSG00000169599.8 0.544 MCM6/ENSG00000076003.4 0.543 SLC25A39/ENSG00000013306.11 0.542 NAP1L1/ENSG00000187109.9 0.54 RP11-849F2.9/ENSG00000269947.1 0.539 IQGAP2/ENSG00000145703.11 0.538 AK4/ENSG00000162433.10 0.537 SLC7A8/ENSG00000092068.14 0.535 ZC3HC1/ENSG00000091732.11 0.534 CTA-29F11.1/ENSG00000260708.1 0.532 ATP1B3/ENSG00000069849.6 0.531 DHFR/ENSG00000228716.2 0.531 SNHG9/ENSG00000255198.2 0.529 STOM/ENSG00000148175.8 0.527 ZNF883/ENSG00000228623.2 0.527 AIG1/ENSG00000146416.12 0.527 CPVL/ENSG00000106066.9 0.525 AC004057.1/ENSG00000196656.6 0.523 MND1/ENSG00000121211.3 0.523 UPF3B/ENSG00000125351.6 0.522 MT1H/ENSG00000205358.3 0.52 FKBP1B/ENSG00000119782.9 0.517 DDX3Y/ENSG00000067048.12 0.514 LSM10/ENSG00000181817.5 0.509 GPM6B/ENSG00000046653.10 0.509 RP11-673C5.1/ENSG00000259781.1 0.508 RP1-241P17.1/ENSG00000229335.1 0.507 UBA6/ENSG00000033178.7 0.506 CTD-2142D14.1/ENSG00000258649.1 0.506 HTATIP2/ENSG00000109854.9 0.506 RP11-498P14.5/ENSG00000203279.2 0.505 NUDT1/ENSG00000106268.11 0.505 UBBP4/ENSG00000263563.1 0.505 AC087645.1/ENSG00000268310.1 0.504 NUP37/ENSG00000075188.4 0.504 RP11-640N20.6/ENSG00000264164.1 0.504 KDM5B/ENSG00000117139.12 0.503 NME1-NME2/ENSG00000243678.6 0.5 ETV1/ENSG00000006468.9 0.5 FLVCR1-AS1/ENSG00000198468.3 0.499 RGS10/ENSG00000148908.10 0.499 RIMKLB/ENSG00000166532.11 0.499 SUCLG2/ENSG00000172340.10 0.498 ACBD6/ENSG00000135847.5 0.498 CASP3/ENSG00000164305.13 0.497 PPM1N/ENSG00000213889.6 0.496 DDX25/ENSG00000109832.8 0.496 ZNF90/ENSG00000213988.5 0.491 PDGFA/ENSG00000197461.9 0.49 METTL5/ENSG00000138382.9 0.488 MT1G/ENSG00000125144.9 0.487 AC073346.2/ENSG00000214194.4 0.486 TIMM8A/ENSG00000126953.5 0.48 ITGB5/ENSG00000082781.6 0.478 GFPT2/ENSG00000131459.8 0.477 C1D/ENSG00000197223.7 0.477 FLVCR1/ENSG00000162769.8 0.477 PPM1B/ENSG00000138032.16 0.477 OAT/ENSG00000065154.7 0.475 PSMB10/ENSG00000205220.7 0.474 PPP2R2B/ENSG00000156475.14 0.472 DIDO1/ENSG00000101191.12 0.47 ZNF649/ENSG00000198093.6 0.47 S100A6/ENSG00000197956.5 0.468 QSER1/ENSG00000060749.10 0.466 PHF5A/ENSG00000100410.3 0.465 IMPA2/ENSG00000141401.7 0.464 INPP5F/ENSG00000198825.7 0.462 TLK1/ENSG00000198586.9 0.462 AP000459.4/ENSG00000228592.1 0.462 DPYSL3/ENSG00000113657.8 0.461 C16ORF62/ENSG00000103544.10 0.461 RP5-1172N10.3/ENSG00000270155.1 0.461 IPO7/ENSG00000205339.5 0.455 DNAJC18/ENSG00000170464.5 0.454 FAM171B/ENSG00000144369.8 0.454 AC119673.1/ENSG00000268313.1 0.454 S100PBP/ENSG00000116497.13 0.454 SRM/ENSG00000116649.5 0.454 EIF2D/ENSG00000143486.11 0.454 PLTP/ENSG00000100979.10 0.452 FZD7/ENSG00000155760.1 0.45 PPIAP22/ENSG00000198618.4 0.448 TP53/ENSG00000141510.11 0.446 ITGA6/ENSG00000091409.10 0.446 TTC39C/ENSG00000168234.8 0.443 FABP3/ENSG00000121769.3 0.44 NFYB/ENSG00000120837.3 0.435 ZDHHC13/ENSG00000177054.9 0.434 TRAP1/ENSG00000126602.6 0.433 PPP1CC/ENSG00000186298.7 0.433 ESCO1/ENSG00000141446.6 0.43 XRCC4/ENSG00000152422.11 0.43 NUDT21/ENSG00000167005.9 0.429 TUBA4A/ENSG00000127824.9 0.428 TRA2A/ENSG00000164548.6 0.426 C8ORF59/ENSG00000176731.7 0.425 TCEAL7/ENSG00000182916.7 0.424 MCM3/ENSG00000112118.12 0.422 TPM2/ENSG00000198467.8 0.419 CTB-151G24.1/ENSG00000267696.2 0.418 LRAT/ENSG00000121207.7 0.416 ZNF22/ENSG00000165512.4 0.415 AC012146.7/ENSG00000234327.2 0.415 FGFBP3/ENSG00000174721.9 0.415 TBC1D7/ENSG00000145979.12 0.414 CPT1C/ENSG00000169169.10 0.414 LINC00599/ENSG00000253230.1 0.413 UCP2/ENSG00000175567.3 0.412 CARHSP1/ENSG00000153048.6 0.411 FBXO3/ENSG00000110429.9 0.411 CTB-63M22.1/ENSG00000229119.3 0.41 CDH3/ENSG00000062038.9 0.41 GTF2I/ENSG00000077809.8 0.41 UBE2E3/ENSG00000170035.11 0.408 IFT27/ENSG00000100360.10 0.406 ZNF826P/ENSG00000231205.7 0.406 GPC4/ENSG00000076716.7 0.405 HPS3/ENSG00000163755.4 0.403 AKAP7/ENSG00000118507.11 0.402 C16ORF13/ENSG00000130731.11 0.399 CCDC152/ENSG00000198865.5 0.398 RABGGTB/ENSG00000137955.11 0.397 SLC39A1/ENSG00000143570.13 0.397 FAM64A/ENSG00000129195.10 0.394 RAB5A/ENSG00000144566.6 0.394 AIF1L/ENSG00000126878.8 0.393 MFAP4/ENSG00000166482.7 0.392 CCDC34/ENSG00000109881.12 0.392 SSU72/ENSG00000160075.10 0.392 UGT8/ENSG00000174607.6 0.392 FOXN3/ENSG00000053254.11 0.391 AL358113.1/ENSG00000269295.1 0.391 SLC6A15/ENSG00000072041.12 0.391 TNRC6B/ENSG00000100354.15 0.39 MIER1/ENSG00000198160.10 0.39 AMD1/ENSG00000123505.10 0.39 SYT6/ENSG00000134207.8 0.39 APOO/ENSG00000184831.9 0.389 GLRX/ENSG00000173221.9 0.388 AEBP2/ENSG00000139154.10 0.388 RPL18AP3/ENSG00000213442.4 0.386 G3BP2/ENSG00000138757.10 0.385 SELM/ENSG00000198832.6 0.384 TATDN3/ENSG00000203705.5 0.381 CTD-2006C1.2/ENSG00000219665.4 0.381 SAMHD1/ENSG00000101347.7 0.378 RP11-148B6.2/ENSG00000250046.3 0.378 ATP1B2/ENSG00000129244.4 0.375 ROR1/ENSG00000185483.7 0.374 SNX27/ENSG00000143376.8 0.374 CDA/ENSG00000158825.5 0.373 RP1-46F2.2/ENSG00000185847.3 0.373 TMPO/ENSG00000120802.9 0.371 DCP2/ENSG00000172795.11 0.371 LINC00545/ENSG00000236094.1 0.37 CD200/ENSG00000091972.13 0.369 ASS1/ENSG00000130707.13 0.368 MYO1E/ENSG00000157483.4 0.367 MRPS30/ENSG00000112996.5 0.367 CCND1/ENSG00000110092.3 0.366 MRPS34/ENSG00000074071.9 0.366 PROCR/ENSG00000101000.4 0.365 DCPS/ENSG00000110063.4 0.365 MIR4454/ENSG00000253348.1 0.365 POLE4/ENSG00000115350.7 0.365 CAMLG/ENSG00000164615.3 0.363 PRPS1/ENSG00000147224.6 0.363 SNCA/ENSG00000145335.11 0.362 GLO1/ENSG00000124767.6 0.362 BBS7/ENSG00000138686.5 0.361 ZNF260/ENSG00000254004.2 0.359 FAM96A/ENSG00000166797.6 0.359 NPM3/ENSG00000107833.6 0.359 ARHGEF10/ENSG00000104728.11 0.357 NTHL1/ENSG00000065057.2 0.356 ZFR2/ENSG00000105278.6 0.354 CWC27/ENSG00000153015.11 0.351 BNIP1/ENSG00000113734.13 0.35 MSN/ENSG00000147065.11 0.35 RP11-145P16.3/ENSG00000270523.1 0.349 PBX1/ENSG00000185630.13 0.349 RPS27L/ENSG00000185088.8 0.348 CCDC88A/ENSG00000115355.11 0.348 TMEM45A/ENSG00000181458.6 0.347 OTUD6B/ENSG00000155100.6 0.347 SUPV3L1/ENSG00000156502.9 0.346 RP11-543P15.1/ENSG00000227081.4 0.346 CENPH/ENSG00000153044.5 0.346 RP11-122A3.2/ENSG00000253250.2 0.346 ZNF431/ENSG00000196705.4 0.345 MRS2/ENSG00000124532.10 0.344 XPOT/ENSG00000184575.7 0.34 KLK8/ENSG00000129455.11 0.34 ALG6/ENSG00000088035.11 0.34 MBOAT1/ENSG00000172197.9 0.339 KCTD14/ENSG00000151364.11 0.338 WDHD1/ENSG00000198554.7 0.338 DHCR7/ENSG00000172893.11 0.337 RP11-572P18.1/ENSG00000220842.5 0.337 CTBP2/ENSG00000175029.12 0.335 TCEAL2/ENSG00000184905.4 0.333 HK1/ENSG00000156515.16 0.333 EAF2/ENSG00000145088.4 0.331 PYCR1/ENSG00000183010.12 0.331 CRIP3/ENSG00000146215.9 0.329 EIF4B/ENSG00000063046.13 0.328 HAX1/ENSG00000143575.10 0.328 ZNF134/ENSG00000213762.6 0.327 RN7SL1/ENSG00000258486.1 0.327 AFMID/ENSG00000183077.11 0.326 PKIB/ENSG00000135549.8 0.326 RP11-277P12.10/ENSG00000256288.1 0.324 RPRD1A/ENSG00000141425.13 0.323 HHLA3/ENSG00000197568.9 0.323 CTB-13H5.1/ENSG00000214485.5 0.323 MT2A/ENSG00000125148.6 0.322 L3MBTL3/ENSG00000198945.3 0.321 ARGLU1/ENSG00000134884.9 0.321 NTS/ENSG00000133636.6 0.32 METTL18/ENSG00000171806.7 0.319 HLA-DPB2/ENSG00000224557.3 0.317 DPY30/ENSG00000162961.9 0.317 SRGAP2/ENSG00000163486.8 0.316 BCL2L12/ENSG00000126453.5 0.314 OSBPL10/ENSG00000144645.9 0.313 ELL3/ENSG00000128886.7 0.313 ARHGEF9/ENSG00000131089.9 0.313 CPSF6/ENSG00000111605.12 0.313 GRTP1/ENSG00000139835.9 0.312 TRAF3IP2-AS1/ENSG00000231889.2 0.312 SWAP70/ENSG00000133789.10 0.31 CLDN6/ENSG00000184697.6 0.309 NFE2L3/ENSG00000050344.7 0.309 RP11-431J24.2/ENSG00000238178.2 0.308 MCM4/ENSG00000104738.12 0.307 GPR19/ENSG00000183150.3 0.307 MLK4/ENSG00000143674.6 0.306 ANKRD18CP/ENSG00000159712.10 0.306 AL021707.1/ENSG00000203583.2 0.305 ZNF57/ENSG00000171970.8 0.305 UBE2D2/ENSG00000131508.11 0.304 RP3-399L15.3/ENSG00000228624.2 0.303 NPEPPS/ENSG00000141279.9 0.303 BBX/ENSG00000114439.14 0.3 CTD-2058B24.2/ENSG00000259048.1 0.3 BBS9/ENSG00000122507.16 0.3 TUBG1/ENSG00000131462.3 0.3 MFAP2/ENSG00000117122.9 0.299 ENO2/ENSG00000111674.3 0.298 SMIM19/ENSG00000176209.6 0.298 C1ORF21/ENSG00000116667.7 0.298 FADS2/ENSG00000134824.9 0.296 TIMM9/ENSG00000100575.9 0.296 C19ORF33/ENSG00000167644.7 0.295 TXLNG/ENSG00000086712.8 0.294 AC003029.1/ENSG00000248594.2 0.292 EEF1A1P5/ENSG00000196205.7 0.291 MKRN1/ENSG00000133606.6 0.29 AP000688.14/ENSG00000230212.2 0.29 FILIP1/ENSG00000118407.9 0.289 KIAA1467/ENSG00000084444.9 0.288 YIF1B/ENSG00000167645.12 0.287 RP11-452F19.3/ENSG00000228106.1 0.287 PRICKLE1/ENSG00000139174.6 0.285 FOXH1/ENSG00000160973.7 0.285 HMGN3/ENSG00000118418.10 0.284 NDUFAB1/ENSG00000004779.5 0.284 DPPA5/ENSG00000203909.3 0.283 ACAD8/ENSG00000151498.7 0.282 CALB1/ENSG00000104327.3 0.281 NME3/ENSG00000103024.3 0.28 DLGAP5/ENSG00000126787.8 0.28 TUBA1C/ENSG00000167553.10 0.279 KRTCAP3/ENSG00000157992.8 0.279 AC140481.1/ENSG00000178162.4 0.278 ZNF114/ENSG00000178150.4 0.278 RP11-508N12.4/ENSG00000242631.1 0.277 NDUFA7/ENSG00000267855.1 0.276 MIR17HG/ENSG00000215417.5 0.276 TMEM256/ENSG00000205544.3 0.276 HEY2/ENSG00000135547.4 0.276 PRKCQ-AS1/ENSG00000237943.1 0.274 LRRN1/ENSG00000175928.5 0.273 SLC25A1/ENSG00000100075.5 0.273 FRAT2/ENSG00000181274.5 0.272 MGME1/ENSG00000125871.9 0.272 ATM/ENSG00000149311.12 0.272 PIM1/ENSG00000137193.9 0.272 KIAA0146/ENSG00000164808.12 0.27 CYB5A/ENSG00000166347.13 0.27 PARD6B/ENSG00000124171.4 0.27 TUBB6/ENSG00000176014.8 0.269 SUZ12P/ENSG00000264538.2 0.268 FXYD6/ENSG00000137726.11 0.266 RP11-568A7.2/ENSG00000228648.1 0.266 RP11-1100L3.7/ENSG00000257663.1 0.265 RAB31/ENSG00000168461.8 0.264 EMC2/ENSG00000104412.3 0.264 NANOGP8/ENSG00000255192.3 0.263 MAP4K1/ENSG00000104814.8 0.263 CDO1/ENSG00000129596.4 0.261 PSMD1/ENSG00000173692.8 0.261 RBM26/ENSG00000139746.11 0.261 CNTNAP2/ENSG00000174469.13 0.258 DDX18/ENSG00000088205.8 0.257 GPR176/ENSG00000166073.4 0.256 PPP1R1C/ENSG00000150722.6 0.255 MSL3P1/ENSG00000224287.2 0.254 TMSB4X/ENSG00000205542.6 0.254 DPPA2/ENSG00000163530.4 0.253 APOBEC3C/ENSG00000244509.2 0.252 CALM1/ENSG00000198668.6 0.251 PPP1R14B/ENSG00000173457.6 0.251 ZNF239/ENSG00000196793.9 Overrepresented GO terms in EP #7: Term Pvalue somatic stem cell population maintenance 1.73E-06 organic acid metabolic process 3.94E-06 nitrogen compound metabolic process 8.52E-06 nucleoside metabolic process 9.74E-05 small molecule biosynthetic process 0.000260233 nucleobase-containing compound metabolic process 0.00028498 G1/S transition of mitotic cell cycle 0.000307456 cell cycle phase transition 0.000352792 nucleoside triphosphate metabolic process 0.000386894 mitotic cell cycle process 0.000504845 purine ribonucleoside monophosphate metabolic process 0.000527835 maintenance of cell number 0.000545383 purine nucleobase biosynthetic process 0.000730408 nucleoside monophosphate metabolic process 0.000897672 oxidation-reduction process 0.000936451 cellular component organization or biogenesis 0.001044429 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 0.001184394 purine ribonucleoside triphosphate metabolic process 0.00137475 cellular process 0.001514359 S-adenosylmethioninamine metabolic process 0.002213939 respiratory electron transport chain 0.002583586 purine ribonucleoside metabolic process 0.002858146 cellular amino acid biosynthetic process 0.002925275 cofactor metabolic process 0.003254864 alpha-amino acid biosynthetic process 0.003399456 cellular biosynthetic process 0.003911704 oxidative phosphorylation 0.004015965 energy derivation by oxidation of organic compounds 0.004307211 alcohol biosynthetic process 0.004959292 cell cycle 0.005082681 guanosine-containing compound biosynthetic process 0.005084729 response to X-ray 0.005625447 single-organism process 0.005753793 carboxylic acid metabolic process 0.006588292 mitochondrial ATP synthesis coupled electron transport 0.007550166 secondary alcohol metabolic process 0.008309378 cholesterol biosynthetic process via desmosterol 0.008594452 cholesterol biosynthetic process via lathosterol 0.008594452 organonitrogen compound biosynthetic process 0.009535695 glutamine metabolic process 0.009804254 response to vitamin 0.010639307 cholesterol biosynthetic process 0.011717833 monocarboxylic acid metabolic process 0.013680414 cellular nitrogen compound biosynthetic process 0.013943858 deoxyribonucleotide catabolic process 0.014239052 fatty acid biosynthetic process 0.017823204 sterol metabolic process 0.017823204 response to interferon-alpha 0.019078663 deoxyribose phosphate catabolic process 0.019078663 protein tetramerization 0.020251373 organic cyclic compound biosynthetic process 0.020403578 organophosphate metabolic process 0.021788784 apoptotic process 0.022983466 viral latency 0.023007599 negative regulation of cell cycle process 0.02321946 organonitrogen compound catabolic process 0.024178886 pigment metabolic process 0.024936279 negative regulation of response to DNA damage stimulus 0.025354555 negative regulation of cellular process 0.026585163 purine nucleoside biosynthetic process 0.026926355 cell death 0.029586812 coenzyme biosynthetic process 0.030556684 negative regulation of cellular macromolecule biosynthetic process 0.030580444 serine family amino acid metabolic process 0.031372254 long-chain fatty-acyl-CoA biosynthetic process 0.031372254 glycosyl compound biosynthetic process 0.033002878 macromolecular complex subunit organization 0.033282241 determination of adult lifespan 0.033437033 cellular response to X-ray 0.033437033 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0.033437033 response to inorganic substance 0.035686417 purine nucleotide metabolic process 0.037278956 negative regulation of nitrogen compound metabolic process 0.039148859 negative regulation of developmental process 0.039754062 cell communication by electrical coupling involved in cardiac conduction 0.041068836 regulation of mitotic cell cycle phase transition 0.042321845 cell division 0.04341123 negative regulation of cell projection organization 0.04375817 mitochondrial respiratory chain complex I assembly 0.048369767 --------------------------------------------- "EP #8: 272 cells, 358 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 0.285714285714286, stage2_: 0.573529411764706, stage3_: 0.457142857142857, St4_3_: 0.390804597701149, stage4: 0.228571428571429, St5_3_: 0.26027397260274, stage5_: 0.15625, stage6.2_: 0.207317073170732, stage6.7_: 0.328947368421053, stage6.14_: 0.134328358208955, " Top Genes: 2.958 HMGB2/ENSG00000164104.7 2.649 CKS1B/ENSG00000173207.8 2.632 NUSAP1/ENSG00000137804.8 2.491 UBE2C/ENSG00000175063.12 2.269 PTTG1/ENSG00000164611.8 2.117 CDK1/ENSG00000170312.11 2.081 CCNB1/ENSG00000134057.10 1.913 MAD2L1/ENSG00000164109.8 1.891 CCNB2/ENSG00000157456.3 1.878 KIAA0101/ENSG00000166803.5 1.792 CENPF/ENSG00000117724.8 1.704 TOP2A/ENSG00000131747.10 1.697 KPNA2/ENSG00000182481.4 1.683 UBE2T/ENSG00000077152.5 1.682 AURKB/ENSG00000178999.8 1.681 TPX2/ENSG00000088325.11 1.627 BIRC5/ENSG00000089685.9 1.558 PCNA/ENSG00000132646.6 1.469 RP11-161H23.5/ENSG00000258232.2 1.444 CKS2/ENSG00000123975.4 1.386 KIF23/ENSG00000137807.9 1.372 SMC4/ENSG00000113810.11 1.358 ZWINT/ENSG00000122952.12 1.297 MLF1IP/ENSG00000151725.7 1.272 TMSB15A/ENSG00000158164.6 1.271 TUBB4B/ENSG00000188229.5 1.267 TRIM59/ENSG00000213186.3 1.236 CENPW/ENSG00000203760.4 1.218 DLGAP5/ENSG00000126787.8 1.212 CENPK/ENSG00000123219.8 1.207 PRC1/ENSG00000198901.9 1.186 CDKN3/ENSG00000100526.15 1.181 CENPN/ENSG00000166451.9 1.174 CDC20/ENSG00000117399.9 1.161 GMNN/ENSG00000112312.5 1.156 BUB3/ENSG00000154473.13 1.15 ORC6/ENSG00000091651.4 1.148 ANP32E/ENSG00000143401.10 1.148 KIF22/ENSG00000079616.8 1.082 RRM1/ENSG00000167325.10 1.049 RAD51AP1/ENSG00000111247.10 1.039 HELLS/ENSG00000119969.10 1.025 FANCD2/ENSG00000144554.6 1.002 ARL6IP1/ENSG00000170540.10 0.995 NDC80/ENSG00000080986.7 0.993 TK1/ENSG00000167900.7 0.978 CKAP2/ENSG00000136108.10 0.955 CCDC150/ENSG00000144395.13 0.935 RNASEH2A/ENSG00000104889.4 0.927 BUB1B/ENSG00000156970.8 0.922 AC087645.1/ENSG00000268310.1 0.922 VRK1/ENSG00000100749.3 0.921 RRM2/ENSG00000171848.9 0.92 NUP107/ENSG00000111581.5 0.914 PLK1/ENSG00000166851.10 0.906 MCM3/ENSG00000112118.12 0.905 TMPO/ENSG00000120802.9 0.9 DEPDC1B/ENSG00000035499.8 0.894 TUBA1B/ENSG00000123416.11 0.888 FANCI/ENSG00000140525.13 0.886 KNSTRN/ENSG00000128944.8 0.873 KNTC1/ENSG00000184445.7 0.866 TMEM97/ENSG00000109084.9 0.863 BUB1/ENSG00000169679.10 0.855 TUBA1C/ENSG00000167553.10 0.853 RFC4/ENSG00000163918.6 0.848 SKA2/ENSG00000182628.8 0.837 EXOSC8/ENSG00000120699.8 0.834 MKI67/ENSG00000148773.8 0.833 TTK/ENSG00000112742.5 0.828 DEK/ENSG00000124795.10 0.815 CSE1L/ENSG00000124207.12 0.8 LBR/ENSG00000143815.10 0.797 ECT2/ENSG00000114346.9 0.794 CHEK1/ENSG00000149554.8 0.792 NUF2/ENSG00000143228.8 0.776 CSRP2/ENSG00000175183.5 0.773 ANLN/ENSG00000011426.6 0.772 PARPBP/ENSG00000185480.7 0.76 MELK/ENSG00000165304.3 0.759 CDCA3/ENSG00000111665.7 0.758 HMMR/ENSG00000072571.14 0.755 HAT1/ENSG00000128708.8 0.751 TMEM106C/ENSG00000134291.7 0.749 GGH/ENSG00000137563.7 0.733 MCM7/ENSG00000166508.13 0.728 RANBP1/ENSG00000099901.12 0.726 ZNF93/ENSG00000184635.9 0.724 AURKA/ENSG00000087586.13 0.719 CENPM/ENSG00000100162.10 0.717 B2M/ENSG00000166710.12 0.713 RFC3/ENSG00000133119.8 0.706 CTC-260E6.10/ENSG00000271524.1 0.696 DDX39A/ENSG00000123136.10 0.695 PRIM1/ENSG00000198056.8 0.679 DTYMK/ENSG00000168393.8 0.673 KIF20A/ENSG00000112984.7 0.657 PTPLAD1/ENSG00000074696.7 0.655 CDCA8/ENSG00000134690.6 0.653 CKAP5/ENSG00000175216.10 0.652 MCM4/ENSG00000104738.12 0.65 EBP/ENSG00000147155.6 0.646 LSM5/ENSG00000106355.5 0.642 CTB-175P5.4/ENSG00000269416.1 0.633 GGCT/ENSG00000006625.13 0.63 CENPV/ENSG00000166582.5 0.627 KIF18A/ENSG00000121621.6 0.625 HIST1H1B/ENSG00000184357.3 0.625 CKAP2L/ENSG00000169607.8 0.624 NEK2/ENSG00000117650.8 0.623 FANCL/ENSG00000115392.7 0.623 TROAP/ENSG00000135451.8 0.615 MIS18BP1/ENSG00000129534.9 0.614 CTSL2/ENSG00000136943.6 0.613 CDC25C/ENSG00000158402.14 0.613 BLM/ENSG00000197299.6 0.604 CCDC77/ENSG00000120647.5 0.601 H2AFV/ENSG00000105968.14 0.598 MGST1/ENSG00000008394.7 0.596 RFC5/ENSG00000111445.9 0.592 ACTL6A/ENSG00000136518.12 0.589 DCP2/ENSG00000172795.11 0.588 CTC-260E6.6/ENSG00000267383.2 0.586 SPC25/ENSG00000152253.4 0.58 DNMT1/ENSG00000130816.10 0.577 MNF1/ENSG00000137288.4 0.576 CENPE/ENSG00000138778.7 0.573 NIF3L1/ENSG00000196290.10 0.572 RHNO1/ENSG00000171792.5 0.568 GINS2/ENSG00000131153.4 0.562 SKA1/ENSG00000154839.5 0.561 TYMS/ENSG00000176890.11 0.56 KIF2C/ENSG00000142945.8 0.56 ESRP1/ENSG00000104413.11 0.555 NCAPG/ENSG00000109805.5 0.554 MPHOSPH9/ENSG00000051825.9 0.552 KIF20B/ENSG00000138182.10 0.541 KIF4A/ENSG00000090889.10 0.538 G2E3/ENSG00000092140.10 0.536 AC004257.3/ENSG00000270143.1 0.533 RP11-673C5.1/ENSG00000259781.1 0.532 NUCKS1/ENSG00000069275.12 0.531 SRGAP2/ENSG00000163486.8 0.53 DCLRE1C/ENSG00000152457.13 0.528 ZNF165/ENSG00000197279.3 0.524 FOXM1/ENSG00000111206.8 0.523 PLK4/ENSG00000142731.6 0.522 SPAG5/ENSG00000076382.10 0.522 NUDT1/ENSG00000106268.11 0.521 ENY2/ENSG00000120533.8 0.517 FUBP1/ENSG00000162613.12 0.511 ESCO2/ENSG00000171320.10 0.511 ASPM/ENSG00000066279.12 0.509 UQCRC1/ENSG00000010256.6 0.507 ZWILCH/ENSG00000174442.7 0.506 ITGB3BP/ENSG00000142856.12 0.504 ACAT2/ENSG00000120437.7 0.501 NCAPD2/ENSG00000010292.8 0.501 ANAPC15/ENSG00000110200.4 0.499 AKR1B1/ENSG00000085662.9 0.496 ALDH7A1/ENSG00000164904.11 0.495 RPA3/ENSG00000106399.7 0.494 SAE1/ENSG00000142230.7 0.488 TMEM209/ENSG00000146842.12 0.488 CDC45/ENSG00000093009.5 0.486 WDHD1/ENSG00000198554.7 0.481 FEN1/ENSG00000168496.3 0.48 SRSF10/ENSG00000188529.10 0.477 KIF15/ENSG00000163808.12 0.474 MMS22L/ENSG00000146263.7 0.474 CDC7/ENSG00000097046.8 0.47 TMEM237/ENSG00000155755.14 0.47 PPIH/ENSG00000171960.6 0.469 KIAA1524/ENSG00000163507.9 0.469 PHGDH/ENSG00000092621.7 0.468 RP11-480I12.5/ENSG00000214796.4 0.462 NCAPH/ENSG00000121152.5 0.461 FAM64A/ENSG00000129195.10 0.458 LIG1/ENSG00000105486.9 0.453 CBX3/ENSG00000122565.14 0.451 CASC5/ENSG00000137812.15 0.451 SGOL2/ENSG00000163535.13 0.449 FBLN1/ENSG00000077942.13 0.449 RPA1/ENSG00000132383.7 0.445 ANKRD20A11P/ENSG00000215559.4 0.445 SMC2/ENSG00000136824.14 0.442 HJURP/ENSG00000123485.6 0.441 H2AFZ/ENSG00000164032.7 0.441 RP11-192H23.4/ENSG00000258472.3 0.44 DTL/ENSG00000143476.13 0.44 NRM/ENSG00000137404.10 0.434 BOLA3/ENSG00000163170.7 0.434 SNRPB/ENSG00000125835.13 0.434 ANAPC11/ENSG00000141552.13 0.433 AC119673.1/ENSG00000268313.1 0.432 HIST1H2BH/ENSG00000197459.2 0.43 DBF4/ENSG00000006634.3 0.429 RP11-360L9.7/ENSG00000253174.2 0.425 CDCA2/ENSG00000184661.9 0.423 NASP/ENSG00000132780.12 0.422 DNA2/ENSG00000138346.10 0.421 CENPJ/ENSG00000151849.10 0.417 MND1/ENSG00000121211.3 0.415 RFC2/ENSG00000049541.6 0.414 ID3/ENSG00000117318.8 0.413 SGOL1/ENSG00000129810.10 0.409 HILPDA/ENSG00000135245.9 0.409 BRCA1/ENSG00000012048.14 0.408 LDHA/ENSG00000134333.9 0.407 CDC6/ENSG00000094804.5 0.407 ACOT7/ENSG00000097021.14 0.406 CENPO/ENSG00000138092.6 0.405 RPP30/ENSG00000148688.9 0.404 DDX6/ENSG00000110367.6 0.404 LRR1/ENSG00000165501.12 0.403 PAICS/ENSG00000128050.4 0.402 HIST1H3B/ENSG00000124693.2 0.401 C19ORF48/ENSG00000167747.9 0.401 TIMELESS/ENSG00000111602.7 0.396 MYBL2/ENSG00000101057.11 0.394 DEPDC1/ENSG00000024526.12 0.391 ZNF738/ENSG00000172687.9 0.391 FABP5/ENSG00000164687.6 0.388 HAUS7/ENSG00000213397.5 0.387 CTDSPL2/ENSG00000137770.9 0.387 DNAJC9/ENSG00000213551.4 0.384 TFAM/ENSG00000108064.6 0.384 WEE1/ENSG00000166483.6 0.383 C3ORF14/ENSG00000114405.6 0.382 HIST1H1E/ENSG00000168298.4 0.381 PBK/ENSG00000168078.5 0.379 SPDL1/ENSG00000040275.12 0.377 INIP/ENSG00000148153.9 0.375 GINS4/ENSG00000147536.7 0.375 LSM3/ENSG00000170860.3 0.374 PSRC1/ENSG00000134222.12 0.373 SMC3/ENSG00000108055.9 0.373 EXOSC9/ENSG00000123737.8 0.369 CHD1/ENSG00000153922.6 0.365 DDAH1/ENSG00000153904.14 0.364 C4ORF21/ENSG00000138658.11 0.363 GLA/ENSG00000102393.4 0.363 SKA3/ENSG00000165480.11 0.361 BRCA2/ENSG00000139618.10 0.359 GEN1/ENSG00000178295.10 0.359 C18ORF54/ENSG00000166845.9 0.358 RPL39L/ENSG00000163923.5 0.354 ARHGAP11B/ENSG00000187951.5 0.354 CLSPN/ENSG00000092853.9 0.353 PDS5B/ENSG00000083642.14 0.351 C1ORF112/ENSG00000000460.12 0.349 CDK2AP1/ENSG00000111328.2 0.347 HIST1H2BD/ENSG00000158373.7 0.344 CASP2/ENSG00000106144.15 0.344 RAD54L/ENSG00000085999.7 0.343 CENPQ/ENSG00000031691.6 0.34 C11ORF82/ENSG00000165490.8 0.339 EMC9/ENSG00000100908.9 0.339 RAD54B/ENSG00000197275.8 0.338 SIVA1/ENSG00000184990.8 0.337 ZNF519/ENSG00000175322.6 0.336 PSAT1/ENSG00000135069.9 0.336 PRIM2/ENSG00000146143.12 0.334 SKP2/ENSG00000145604.11 0.334 KIF11/ENSG00000138160.4 0.333 RACGAP1/ENSG00000161800.8 0.332 ZNF90/ENSG00000213988.5 0.33 USP1/ENSG00000162607.8 0.33 FAM111A/ENSG00000166801.11 0.33 MTHFD1/ENSG00000100714.10 0.329 YEATS4/ENSG00000127337.2 0.328 RNF138/ENSG00000134758.9 0.326 RP11-138C9.1/ENSG00000264558.1 0.326 PSIP1/ENSG00000164985.10 0.325 SUV39H2/ENSG00000152455.11 0.325 RP11-303E16.2/ENSG00000261061.1 0.322 PSMC3IP/ENSG00000131470.10 0.322 GCA/ENSG00000115271.6 0.319 RND3/ENSG00000115963.9 0.319 DHFR/ENSG00000228716.2 0.319 TMEM48/ENSG00000058804.10 0.316 BARD1/ENSG00000138376.6 0.316 CASP6/ENSG00000138794.5 0.316 BORA/ENSG00000136122.11 0.315 HMGA2/ENSG00000149948.9 0.314 PTOV1/ENSG00000104960.11 0.312 PHIP/ENSG00000146247.12 0.311 LSM4/ENSG00000130520.4 0.31 NDUFB6/ENSG00000165264.6 0.308 MRE11A/ENSG00000020922.7 0.307 ZNF695/ENSG00000197472.10 0.305 CHEK2/ENSG00000183765.16 0.302 ARHGAP11A/ENSG00000198826.6 0.302 TRAIP/ENSG00000183763.4 0.302 TTF2/ENSG00000116830.6 0.3 NAA16/ENSG00000172766.14 0.298 PRR11/ENSG00000068489.8 0.298 CDK5RAP2/ENSG00000136861.13 0.297 RFC1/ENSG00000035928.10 0.297 AP2S1/ENSG00000042753.7 0.297 ESYT1/ENSG00000139641.8 0.297 RP11-386G11.10/ENSG00000258017.1 0.296 MIS18A/ENSG00000159055.3 0.296 CTPS1/ENSG00000171793.9 0.296 GINS1/ENSG00000101003.8 0.296 RSRC1/ENSG00000174891.8 0.294 FAM83D/ENSG00000101447.9 0.292 SMS/ENSG00000102172.11 0.292 MCM6/ENSG00000076003.4 0.292 RTKN2/ENSG00000182010.6 0.29 RNFT2/ENSG00000135119.10 0.289 PRCP/ENSG00000137509.5 0.289 DSN1/ENSG00000149636.10 0.289 ORC1/ENSG00000085840.7 0.288 C4ORF46/ENSG00000205208.4 0.287 TRIM28/ENSG00000130726.7 0.286 RAD18/ENSG00000070950.5 0.286 RAD51C/ENSG00000108384.10 0.286 POLE2/ENSG00000100479.7 0.285 MCM5/ENSG00000100297.10 0.284 PIF1/ENSG00000140451.8 0.284 ZDHHC6/ENSG00000023041.7 0.283 DCK/ENSG00000156136.5 0.281 SFR1/ENSG00000156384.10 0.281 SPC24/ENSG00000161888.7 0.279 TACC3/ENSG00000013810.14 0.279 FANCG/ENSG00000221829.5 0.278 EFCAB11/ENSG00000140025.11 0.277 OIP5/ENSG00000104147.4 0.276 ZNF331/ENSG00000130844.12 0.274 DPYSL2/ENSG00000092964.11 0.274 SEPT10/ENSG00000186522.10 0.273 CCDC18/ENSG00000122483.13 0.271 CCNF/ENSG00000162063.8 0.271 CEP78/ENSG00000148019.8 0.27 CTD-2291D10.4/ENSG00000267886.1 0.27 MCM10/ENSG00000065328.12 0.269 CDCA7L/ENSG00000164649.15 0.268 MGME1/ENSG00000125871.9 0.265 PRPS2/ENSG00000101911.8 0.265 LSM2/ENSG00000204392.6 0.264 HIST1H1C/ENSG00000187837.2 0.264 CCDC14/ENSG00000175455.10 0.264 MYEF2/ENSG00000104177.13 0.264 ARHGAP19/ENSG00000269891.1 0.264 FBXO5/ENSG00000112029.5 0.264 ASF1B/ENSG00000105011.4 0.262 COMMD4/ENSG00000140365.11 0.262 GABPB1/ENSG00000104064.11 0.261 CEP152/ENSG00000103995.9 0.26 AUNIP/ENSG00000127423.6 0.26 CUL1/ENSG00000055130.11 0.258 BAZ1B/ENSG00000009954.6 0.257 AC010620.1/ENSG00000256240.1 0.252 POC1A/ENSG00000164087.3 0.251 PHF19/ENSG00000119403.9 0.25 SMC1A/ENSG00000072501.12 0.25 NUPL1/ENSG00000139496.11 Overrepresented GO terms in EP #8: Term Pvalue organelle fission 3.82E-68 cell division 8.37E-56 sister chromatid cohesion 3.96E-38 nuclear chromosome segregation 1.65E-30 cell cycle 6.10E-29 cell cycle phase transition 4.72E-26 mitotic nuclear division 4.88E-24 cellular component organization 4.75E-18 telomere maintenance via recombination 4.74E-17 chromatin assembly or disassembly 9.93E-17 metaphase/anaphase transition of cell cycle 1.15E-15 DNA replication initiation 1.36E-15 cellular response to stress 1.48E-15 G2/M transition of mitotic cell cycle 1.60E-15 DNA packaging 2.10E-15 mitotic sister chromatid separation 2.69E-15 protein-DNA complex subunit organization 3.66E-15 spindle checkpoint 1.01E-14 DNA synthesis involved in DNA repair 2.70E-14 mitotic cell cycle process 7.53E-14 DNA repair 8.77E-13 CENP-A containing nucleosome assembly 1.53E-12 mitotic sister chromatid segregation 1.98E-12 negative regulation of cell cycle phase transition 5.87E-12 double-strand break repair via homologous recombination 9.66E-12 telomere organization 1.31E-11 ATP-dependent chromatin remodeling 1.41E-11 heterocycle metabolic process 2.07E-11 cellular aromatic compound metabolic process 2.21E-11 mitotic cell cycle checkpoint 2.70E-11 mitotic spindle organization 3.90E-11 organic cyclic compound metabolic process 9.80E-11 spindle organization 1.15E-10 "DNA damage response, detection of DNA damage " 2.41E-10 negative regulation of mitotic metaphase/anaphase transition 5.55E-10 G1/S transition of mitotic cell cycle 6.41E-10 DNA conformation change 8.30E-10 negative regulation of nuclear division 1.10E-09 negative regulation of mitotic sister chromatid segregation 1.26E-09 cell cycle DNA replication 1.26E-09 DNA replication 1.34E-09 nucleic acid metabolic process 2.11E-09 cellular nitrogen compound metabolic process 2.37E-09 postreplication repair 2.47E-09 error-prone translesion synthesis 2.54E-09 negative regulation of chromosome segregation 2.69E-09 DNA strand elongation involved in DNA replication 3.84E-09 chromosome localization 1.06E-08 "nucleotide-excision repair, DNA gap filling " 2.08E-08 anaphase-promoting complex-dependent catabolic process 2.26E-08 regulation of DNA-dependent DNA replication 2.59E-08 single-organism organelle organization 5.13E-08 chromosome segregation 5.55E-08 regulation of transcription involved in G1/S transition of mitotic cell cycle 7.51E-08 error-free translesion synthesis 9.68E-08 interstrand cross-link repair 1.27E-07 cellular macromolecular complex assembly 1.28E-07 negative regulation of chromosome organization 1.38E-07 DNA recombination 1.80E-07 mitotic spindle assembly checkpoint 2.34E-07 DNA duplex unwinding 3.22E-07 regulation of cell cycle 3.33E-07 centrosome organization 3.48E-07 mitotic cytokinesis 8.12E-07 mitotic DNA replication 9.72E-07 mitotic DNA integrity checkpoint 1.25E-06 meiosis I 1.34E-06 regulation of attachment of spindle microtubules to kinetochore 1.48E-06 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition 1.73E-06 strand displacement 1.75E-06 regulation of signal transduction by p53 class mediator 2.23E-06 protein sumoylation 3.24E-06 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36E-06 regulation of ubiquitin protein ligase activity 4.94E-06 protein localization to kinetochore 5.30E-06 chromosome organization 5.75E-06 reproduction 6.14E-06 anatomical structure homeostasis 6.43E-06 double-strand break repair via break-induced replication 7.72E-06 mitotic chromosome condensation 9.11E-06 positive regulation of cell cycle process 1.01E-05 negative regulation of DNA replication 1.37E-05 regulation of cell cycle G2/M phase transition 1.72E-05 centrosome separation 1.93E-05 protein localization to chromosome 2.37E-05 nucleic acid phosphodiester bond hydrolysis 2.44E-05 positive regulation of ubiquitin-protein transferase activity 2.66E-05 "nucleotide-excision repair, DNA incision, 5'-to lesion " 2.81E-05 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 2.99E-05 attachment of spindle microtubules to kinetochore 3.32E-05 regulation of mitotic centrosome separation 3.80E-05 histone-serine phosphorylation 3.80E-05 spindle elongation 3.80E-05 cellular macromolecule metabolic process 5.57E-05 regulation of chromosome segregation 7.41E-05 meiotic chromosome segregation 8.20E-05 regulation of chromosome organization 8.42E-05 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8.78E-05 positive regulation of cytokinesis 9.88E-05 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.000106367 positive regulation of DNA-directed DNA polymerase activity 0.000111924 mitotic nuclear envelope disassembly 0.000118165 regulation of mitotic sister chromatid segregation 0.000119865 positive regulation of DNA metabolic process 0.000136442 DNA double-strand break processing 0.000144782 DNA-dependent DNA replication 0.000152529 membrane disassembly 0.00016917 regulation of mitotic cell cycle phase transition 0.000179913 regulation of mitotic spindle checkpoint 0.000184 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.000184056 cell cycle checkpoint 0.000225275 negative regulation of ubiquitin-protein transferase activity 0.000239079 regulation of mitotic metaphase/anaphase transition 0.000239584 signal transduction in response to DNA damage 0.000281737 positive regulation of protein modification by small protein conjugation or removal 0.00029124 regulation of cell cycle arrest 0.000373862 regulation of centrosome cycle 0.000405505 negative regulation of G2/M transition of mitotic cell cycle 0.000439244 positive regulation of proteolysis involved in cellular protein catabolic process 0.000440741 mitotic spindle midzone assembly 0.000504647 regulation of mitotic spindle organization 0.000504647 macromolecule biosynthetic process 0.000573006 mitotic G2 DNA damage checkpoint 0.000591965 kinetochore organization 0.000591965 protein complex biogenesis 0.000615149 mitotic spindle assembly 0.000695964 chromatin modification 0.000721923 transcription-coupled nucleotide-excision repair 0.00076189 lagging strand elongation 0.000892886 microtubule polymerization or depolymerization 0.000956298 regulation of mitotic nuclear division 0.001223672 positive regulation of mitotic nuclear division 0.00122937 mitotic metaphase plate congression 0.001279363 "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest " 0.001338249 meiotic chromosome condensation 0.001418879 "DNA replication, removal of RNA primer " 0.001418879 DNA unwinding involved in DNA replication 0.001462803 positive regulation of chromosome segregation 0.001493919 intracellular signal transduction involved in G1 DNA damage checkpoint 0.001515476 "retrograde vesicle-mediated transport, Golgi to ER " 0.001634319 signal transduction involved in mitotic cell cycle checkpoint 0.001711864 signal transduction involved in mitotic DNA damage checkpoint 0.001711864 response to ionizing radiation 0.001780184 regulation of cell division 0.001789065 G2 DNA damage checkpoint 0.001825169 response to UV 0.002088738 signal transduction involved in DNA integrity checkpoint 0.002168618 regulation of cellular protein catabolic process 0.002252921 primary metabolic process 0.002271087 cellular biosynthetic process 0.002283644 regulation of mitotic cell cycle 0.002287249 positive regulation of protein catabolic process 0.00261409 mitotic recombination 0.002755438 centromere complex assembly 0.002861508 deoxyribonucleotide biosynthetic process 0.003331729 chromosome breakage 0.003490263 negative regulation of DNA endoreduplication 0.003490263 spindle assembly involved in meiosis 0.003490263 mitotic G1 DNA damage checkpoint 0.003769535 protein ubiquitination 0.003818981 spindle localization 0.003954123 regulation of double-strand break repair 0.004634476 nucleobase-containing compound biosynthetic process 0.004712588 cytokinesis 0.004744773 single organism reproductive process 0.004847278 replication fork processing 0.004996617 antigen processing and presentation of exogenous antigen 0.005334145 positive regulation of mitotic cell cycle phase transition 0.005513329 serine family amino acid biosynthetic process 0.006510543 cytokinetic process 0.006510543 regulation of centriole replication 0.006510543 regulation of DNA metabolic process 0.006628196 base-excision repair 0.007246281 regulation of cell cycle G1/S phase transition 0.007819196 chromosome condensation 0.008148397 cell proliferation 0.010523063 response to abiotic stimulus 0.010605118 antigen processing and presentation of peptide antigen 0.010644688 protein localization to microtubule cytoskeleton 0.010762688 regulation of cyclin-dependent protein serine/threonine kinase activity 0.010833786 nuclear envelope organization 0.010833786 DNA replication checkpoint 0.01143916 deoxyribonucleoside monophosphate biosynthetic process 0.011827527 positive regulation of mitotic cell cycle spindle assembly checkpoint 0.011827527 regulation of response to DNA damage stimulus 0.012707488 organelle assembly 0.01272212 centriole assembly 0.012776729 macromolecular complex subunit organization 0.015183187 microtubule cytoskeleton organization 0.015942707 protein modification by small protein conjugation or removal 0.016216694 actomyosin contractile ring assembly 0.016776808 spindle assembly involved in female meiosis I 0.016776808 peptidyl-amino acid modification 0.017042908 protein complex subunit organization 0.017223495 metaphase plate congression 0.01726196 positive regulation of cellular catabolic process 0.017573015 signal transduction by p53 class mediator 0.018266077 attachment of mitotic spindle microtubules to kinetochore 0.018621256 protein K6-linked ubiquitination 0.018621256 regulation of organelle organization 0.018958952 regulation of microtubule cytoskeleton organization 0.019282919 negative regulation of protein modification by small protein conjugation or removal 0.020009127 mismatch repair 0.020546409 regulation of DNA replication 0.022905458 meiotic nuclear division 0.025818658 negative regulation of G1/S transition of mitotic cell cycle 0.026227616 negative regulation of cell cycle process 0.026228699 regulation of single stranded viral RNA replication via double stranded DNA intermediate 0.027485441 modification-dependent macromolecule catabolic process 0.030856334 response to cadmium ion 0.031413488 microtubule-based movement 0.035282413 macromolecule catabolic process 0.036481799 inner cell mass cell proliferation 0.038638 negative regulation of centrosome duplication 0.038638 heterochromatin assembly 0.038638 meiotic sister chromatid segregation 0.038638 positive regulation of cell cycle checkpoint 0.038638 regulation of cell cycle checkpoint 0.040183305 histone H3-K9 modification 0.040718659 oocyte maturation 0.041503391 chromatin silencing 0.045409799 double-strand break repair via nonhomologous end joining 0.045894543 cellular response to ionizing radiation 0.045894543 DNA replication-independent nucleosome assembly 0.046697709 nucleosome assembly 0.047196199 establishment of mitotic spindle localization 0.049393266 establishment or maintenance of microtubule cytoskeleton polarity 0.049609401 U1 snRNA 3'-end processing 0.049609401 U5 snRNA 3'-end processing 0.049609401 mitochondrial DNA repair 0.049609401 mitotic telomere maintenance via semi-conservative replication 0.049609401 --------------------------------------------- "EP #9: 109 cells, 339 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0158730158730159, stage2_: 1, stage3_: 0.457142857142857, St4_3_: 0.0689655172413793, stage4: 0.0142857142857143, St5_3_: 0, stage5_: 0, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0.0149253731343284, " Top Genes: 3.636 NPY/ENSG00000122585.3 3.539 TTR/ENSG00000118271.5 3.437 AL590714.1/ENSG00000268387.1 3.412 APOA2/ENSG00000158874.6 2.776 DLK1/ENSG00000185559.9 2.641 IGFBP3/ENSG00000146674.10 2.525 FLRT3/ENSG00000125848.9 2.216 ID2/ENSG00000115738.5 2.186 ANXA2/ENSG00000182718.11 2.083 FLRT2/ENSG00000185070.6 1.995 SLC2A3/ENSG00000059804.11 1.884 SEBOX/ENSG00000109072.7 1.882 CTSC/ENSG00000109861.11 1.857 CTSL1/ENSG00000135047.10 1.854 COL4A6/ENSG00000197565.11 1.801 GSTA2/ENSG00000244067.1 1.794 LINC00261/ENSG00000259974.1 1.765 KRT19/ENSG00000171345.9 1.718 SPARC/ENSG00000113140.6 1.683 EFNA5/ENSG00000184349.8 1.653 RP11-366M4.3/ENSG00000248329.1 1.641 GPC3/ENSG00000147257.9 1.624 RGS2/ENSG00000116741.6 1.612 FN1/ENSG00000115414.14 1.581 AC107016.1/ENSG00000225410.1 1.503 IFITM3/ENSG00000142089.11 1.484 GRB14/ENSG00000115290.5 1.48 SEMA3E/ENSG00000170381.8 1.465 ID3/ENSG00000117318.8 1.462 PLK2/ENSG00000145632.10 1.459 S100A11/ENSG00000163191.5 1.439 ABCA1/ENSG00000165029.11 1.42 SHISA2/ENSG00000180730.4 1.411 CGN/ENSG00000143375.9 1.401 HPX/ENSG00000110169.6 1.4 CTSL2/ENSG00000136943.6 1.387 KRT8/ENSG00000170421.7 1.38 LAMB1/ENSG00000091136.9 1.368 DMD/ENSG00000198947.9 1.354 LIN28A/ENSG00000131914.6 1.328 CADPS/ENSG00000163618.13 1.322 VCAN/ENSG00000038427.11 1.282 TAC3/ENSG00000166863.7 1.241 EFNA1/ENSG00000169242.7 1.233 SPTSSB/ENSG00000196542.4 1.228 KRT18/ENSG00000111057.6 1.168 PROM1/ENSG00000007062.7 1.15 RNA28S5/ENSG00000226958.1 1.134 S100A10/ENSG00000197747.4 1.134 ARRDC3/ENSG00000113369.4 1.133 APOC1/ENSG00000130208.5 1.127 GCA/ENSG00000115271.6 1.12 CA14/ENSG00000118298.5 1.094 GLRX/ENSG00000173221.9 1.062 RGS5/ENSG00000143248.7 1.061 IGDCC4/ENSG00000103742.7 1.059 MUSTN1/ENSG00000243696.3 1.057 LYPD6B/ENSG00000150556.12 1.023 DNMT3A/ENSG00000119772.12 1.022 PRTG/ENSG00000166450.7 0.999 HLA-B/ENSG00000234745.5 0.993 TMEM141/ENSG00000244187.2 0.99 HHEX/ENSG00000152804.6 0.989 CLU/ENSG00000120885.15 0.974 ADD3/ENSG00000148700.9 0.964 SSBP2/ENSG00000145687.11 0.938 TMEM14B/ENSG00000137210.8 0.927 FAM162A/ENSG00000114023.11 0.911 CST3/ENSG00000101439.4 0.898 RP11-161H23.5/ENSG00000258232.2 0.868 SLC16A1/ENSG00000155380.7 0.868 ENPP2/ENSG00000136960.8 0.863 CXXC4/ENSG00000168772.9 0.853 CDH2/ENSG00000170558.4 0.847 VAMP8/ENSG00000118640.6 0.843 FOXP1/ENSG00000114861.14 0.819 HAS2/ENSG00000170961.6 0.818 RPS2/ENSG00000140988.11 0.817 ALCAM/ENSG00000170017.8 0.815 AXL/ENSG00000167601.7 0.815 COL4A5/ENSG00000188153.8 0.808 FAM46A/ENSG00000112773.11 0.798 RHOBTB3/ENSG00000164292.8 0.794 TMEM135/ENSG00000166575.12 0.79 TRIM5/ENSG00000132256.14 0.786 SNHG14/ENSG00000224078.6 0.782 TTC39C/ENSG00000168234.8 0.776 ROBO2/ENSG00000185008.13 0.772 CAMK2D/ENSG00000145349.12 0.769 GLYATL1P2/ENSG00000254717.2 0.766 ID1/ENSG00000125968.7 0.764 SPATS2L/ENSG00000196141.7 0.761 NUDT4/ENSG00000173598.9 0.761 CADM1/ENSG00000182985.11 0.761 KIT/ENSG00000157404.11 0.758 RP11-511B23.1/ENSG00000257345.2 0.758 CDH1/ENSG00000039068.13 0.75 TES/ENSG00000135269.13 0.749 ANXA3/ENSG00000138772.8 0.744 ZFP36L1/ENSG00000185650.8 0.736 MGST1/ENSG00000008394.7 0.735 SMAGP/ENSG00000170545.12 0.725 CSPP1/ENSG00000104218.9 0.725 KANK1/ENSG00000107104.14 0.719 APOM/ENSG00000204444.6 0.716 ELMO1/ENSG00000155849.11 0.715 AK4/ENSG00000162433.10 0.71 TRA2A/ENSG00000164548.6 0.708 PCDH7/ENSG00000169851.11 0.705 AGL/ENSG00000162688.11 0.703 BCAS3/ENSG00000141376.16 0.702 DGKB/ENSG00000136267.9 0.7 ZNF761/ENSG00000160336.10 0.695 SLC39A10/ENSG00000196950.9 0.691 ZNF518B/ENSG00000178163.3 0.676 DPPA4/ENSG00000121570.8 0.668 GSTA1/ENSG00000243955.1 0.664 MRPS9/ENSG00000135972.4 0.663 TLN2/ENSG00000171914.10 0.656 FNDC3B/ENSG00000075420.8 0.656 C5/ENSG00000106804.6 0.649 MMD/ENSG00000108960.3 0.647 SC5D/ENSG00000109929.5 0.647 PRDX6/ENSG00000117592.8 0.646 LPPR1/ENSG00000148123.10 0.646 PGAM1/ENSG00000171314.8 0.641 RP11-466H18.1/ENSG00000244398.1 0.637 UNC5D/ENSG00000156687.6 0.633 CALM3/ENSG00000160014.12 0.632 MAP4K4/ENSG00000071054.11 0.628 PRIM2/ENSG00000146143.12 0.623 GPR126/ENSG00000112414.10 0.622 RP3-368A4.5/ENSG00000271430.1 0.612 VIL1/ENSG00000127831.6 0.611 IFNGR2/ENSG00000159128.10 0.604 ODC1/ENSG00000115758.8 0.598 RP11-449P1.1/ENSG00000256923.1 0.591 FAM126A/ENSG00000122591.7 0.59 VCAN-AS1/ENSG00000249835.2 0.585 RP11-771K4.1/ENSG00000256232.1 0.58 MOV10/ENSG00000155363.14 0.579 RAB25/ENSG00000132698.9 0.577 ZFP36L2/ENSG00000152518.5 0.575 FZD4/ENSG00000174804.3 0.573 PAQR5/ENSG00000137819.9 0.571 SLC40A1/ENSG00000138449.6 0.571 DNAJC15/ENSG00000120675.4 0.57 AC012215.1/ENSG00000233863.1 0.569 CNKSR2/ENSG00000149970.10 0.569 MDH2/ENSG00000146701.6 0.554 TGFB2/ENSG00000092969.7 0.548 ATP2B1/ENSG00000070961.10 0.545 QKI/ENSG00000112531.12 0.545 RAB3C/ENSG00000152932.6 0.543 CDK14/ENSG00000058091.12 0.542 DLC1/ENSG00000164741.10 0.541 SRGAP2/ENSG00000163486.8 0.54 XBP1/ENSG00000100219.12 0.539 EIF4B/ENSG00000063046.13 0.539 FERMT2/ENSG00000073712.9 0.535 RP11-789C1.1/ENSG00000250266.1 0.535 GSTK1/ENSG00000197448.9 0.532 HEPH/ENSG00000089472.12 0.528 ZNF90/ENSG00000213988.5 0.527 MEIS2/ENSG00000134138.14 0.523 ZNF611/ENSG00000213020.4 0.52 AGO1/ENSG00000092847.6 0.517 HMGA1/ENSG00000137309.15 0.516 LITAF/ENSG00000189067.8 0.504 OTX2/ENSG00000165588.12 0.504 DSCR6/ENSG00000183145.4 0.5 DKK1/ENSG00000107984.5 0.497 CTC-260E6.6/ENSG00000267383.2 0.494 ARL15/ENSG00000185305.6 0.493 PTPN13/ENSG00000163629.8 0.493 RP11-480I12.5/ENSG00000214796.4 0.491 TNFAIP8/ENSG00000145779.6 0.489 RP11-122C9.1/ENSG00000137970.7 0.486 CRABP2/ENSG00000143320.4 0.485 BAMBI/ENSG00000095739.7 0.485 CTB-63M22.1/ENSG00000229119.3 0.485 ALDH2/ENSG00000111275.8 0.482 NT5C2/ENSG00000076685.14 0.477 ARHGAP24/ENSG00000138639.13 0.475 PPFIBP2/ENSG00000166387.7 0.469 HABP2/ENSG00000148702.10 0.469 DLG5/ENSG00000151208.12 0.468 MGST2/ENSG00000085871.4 0.468 ADAMTS19/ENSG00000145808.4 0.467 CD200/ENSG00000091972.13 0.467 RP11-572P18.1/ENSG00000220842.5 0.466 CTC-260E6.10/ENSG00000271524.1 0.462 PLD3/ENSG00000105223.14 0.459 SALL1/ENSG00000103449.7 0.456 CD59/ENSG00000085063.10 0.455 PDGFA/ENSG00000197461.9 0.452 FZD5/ENSG00000163251.3 0.448 MCC/ENSG00000171444.13 0.447 TPM2/ENSG00000198467.8 0.446 EIF2AK4/ENSG00000128829.6 0.439 SH3RF1/ENSG00000154447.10 0.437 PRDX4/ENSG00000123131.8 0.437 CTC-524C5.2/ENSG00000263272.1 0.436 GSTO1/ENSG00000148834.8 0.434 UTRN/ENSG00000152818.13 0.429 TRIM6/ENSG00000121236.15 0.426 PEG10/ENSG00000242265.1 0.425 HMGCS2/ENSG00000134240.7 0.424 SMAD9/ENSG00000120693.9 0.423 TTC3/ENSG00000182670.9 0.421 CHST9/ENSG00000154080.8 0.421 TMEFF1/ENSG00000241697.3 0.42 C3ORF58/ENSG00000181744.4 0.419 THOC5/ENSG00000100296.9 0.416 REST/ENSG00000084093.11 0.416 CTB-13H5.1/ENSG00000214485.5 0.416 TTTY14/ENSG00000176728.3 0.415 FOLR1/ENSG00000110195.7 0.413 EPHA4/ENSG00000116106.7 0.41 MTERFD2/ENSG00000122085.11 0.408 SEMA6A/ENSG00000092421.12 0.397 TUFT1/ENSG00000143367.11 0.397 CCKBR/ENSG00000110148.5 0.397 RPL18AP3/ENSG00000213442.4 0.394 ITLN2/ENSG00000158764.6 0.392 FAM184A/ENSG00000111879.14 0.392 CDKAL1/ENSG00000145996.7 0.391 AC007192.6/ENSG00000269145.1 0.39 FKBP7/ENSG00000079150.13 0.388 MEIS1/ENSG00000143995.14 0.387 LPHN2/ENSG00000117114.15 0.385 ID4/ENSG00000172201.6 0.385 SGIP1/ENSG00000118473.16 0.384 NUAK1/ENSG00000074590.9 0.384 EXOC6/ENSG00000138190.12 0.384 LINC00340/ENSG00000238274.2 0.382 PIK3R1/ENSG00000145675.10 0.382 SFRP1/ENSG00000104332.7 0.38 CCNB2/ENSG00000157456.3 0.378 TYRO3/ENSG00000092445.7 0.378 RDX/ENSG00000137710.10 0.378 MAGED1/ENSG00000179222.12 0.374 AC010761.8/ENSG00000264577.1 0.37 TCF7L1/ENSG00000152284.4 0.369 F3/ENSG00000117525.9 0.366 ZBTB16/ENSG00000109906.9 0.364 ONECUT1/ENSG00000169856.6 0.361 EFCAB11/ENSG00000140025.11 0.36 RP11-114G22.1/ENSG00000256995.2 0.359 DFNA5/ENSG00000105928.9 0.358 RP11-701H24.5/ENSG00000270704.1 0.358 C1ORF168/ENSG00000187889.8 0.358 SKA1/ENSG00000154839.5 0.356 NQO1/ENSG00000181019.8 0.354 AGXT2L1/ENSG00000164089.4 0.353 PLS3/ENSG00000102024.11 0.35 FAM117B/ENSG00000138439.10 0.349 FXYD6/ENSG00000137726.11 0.349 ZNF765/ENSG00000196417.8 0.348 KDM1A/ENSG00000004487.11 0.345 ACN9/ENSG00000196636.7 0.345 TRIM59/ENSG00000213186.3 0.344 CXCR4/ENSG00000121966.6 0.344 DDHD1/ENSG00000100523.10 0.344 SP3/ENSG00000172845.9 0.342 USP3/ENSG00000140455.12 0.341 STYX/ENSG00000198252.7 0.34 DNPEP/ENSG00000123992.14 0.339 MAATS1/ENSG00000183833.12 0.338 FAT3/ENSG00000165323.11 0.337 TTL/ENSG00000114999.6 0.336 SSBP3/ENSG00000157216.11 0.333 COMMD8/ENSG00000169019.9 0.329 PSTPIP2/ENSG00000152229.14 0.328 COBLL1/ENSG00000082438.11 0.327 TFF3/ENSG00000160180.14 0.326 ARHGAP26/ENSG00000145819.11 0.323 WDR72/ENSG00000166415.10 0.32 PMEL/ENSG00000185664.10 0.319 AC006978.6/ENSG00000235859.4 0.319 ABCF2/ENSG00000033050.3 0.317 IFITM1/ENSG00000185885.11 0.317 CHL1/ENSG00000134121.5 0.317 FLNB/ENSG00000136068.10 0.313 GATA3/ENSG00000107485.11 0.312 WWC2/ENSG00000151718.11 0.312 PLCXD2/ENSG00000240891.2 0.311 RP11-296O14.3/ENSG00000203739.3 0.31 LTA4H/ENSG00000111144.5 0.31 PRSS1/ENSG00000204983.8 0.309 DOCK1/ENSG00000150760.8 0.308 KIAA1456/ENSG00000250305.4 0.307 RHOU/ENSG00000116574.4 0.306 GLDC/ENSG00000178445.8 0.306 SNORD3A/ENSG00000263934.1 0.306 PGA5/ENSG00000256713.3 0.305 AGK/ENSG00000006530.11 0.303 GALNT7/ENSG00000109586.7 0.301 AKR1C3/ENSG00000196139.7 0.301 EDEM2/ENSG00000088298.7 0.3 FBLN1/ENSG00000077942.13 0.3 EHMT2/ENSG00000204371.7 0.298 LMO3/ENSG00000048540.10 0.298 SYTL5/ENSG00000147041.7 0.296 ZNF702P/ENSG00000242779.2 0.294 LGI2/ENSG00000153012.7 0.294 NDUFA9P1/ENSG00000237406.1 0.294 GGCT/ENSG00000006625.13 0.294 SCG5/ENSG00000166922.4 0.291 SLC2A1/ENSG00000117394.15 0.288 NRP2/ENSG00000118257.12 0.288 MAF/ENSG00000178573.6 0.287 KEL/ENSG00000197993.3 0.287 PCDH17/ENSG00000118946.7 0.285 CDH3/ENSG00000062038.9 0.283 RP11-253M7.1/ENSG00000259426.1 0.283 NUDT1/ENSG00000106268.11 0.282 RP11-216F19.2/ENSG00000270674.1 0.282 FOXA1/ENSG00000129514.4 0.28 AJUBA/ENSG00000129474.11 0.277 ZNF826P/ENSG00000231205.7 0.275 ISL1/ENSG00000016082.10 0.274 CDC37L1/ENSG00000106993.7 0.273 SMAD1/ENSG00000170365.5 0.272 SORD/ENSG00000140263.9 0.27 ERO1L/ENSG00000197930.8 0.267 LRRN1/ENSG00000175928.5 0.265 RP11-3P17.3/ENSG00000234851.3 0.264 RP11-11N9.4/ENSG00000247134.2 0.262 LGMN/ENSG00000100600.10 0.259 RP11-1069G10.1/ENSG00000259370.1 0.257 NEK2/ENSG00000117650.8 0.256 ADAM28/ENSG00000042980.8 0.256 RP11-148B6.1/ENSG00000249532.1 0.255 LBH/ENSG00000213626.7 0.255 OLFML2B/ENSG00000162745.6 0.254 CDR1/ENSG00000184258.5 0.253 IFITM2/ENSG00000185201.12 0.252 KIAA1324/ENSG00000116299.12 Overrepresented GO terms in EP #9: Term Pvalue biological adhesion 1.29E-10 regulation of cell motility 4.71E-08 localization of cell 6.35E-08 cell morphogenesis 4.72E-07 single organism signaling 9.53E-07 positive regulation of cellular component movement 2.69E-06 positive regulation of locomotion 2.83E-06 single-organism developmental process 4.50E-06 regulation of multicellular organismal development 5.78E-06 cell communication 5.88E-06 blood vessel morphogenesis 7.10E-06 cellular response to chemical stimulus 1.06E-05 central nervous system development 1.46E-05 response to wounding 1.52E-05 ameboidal-type cell migration 1.63E-05 cell development 1.80E-05 cell-cell adhesion 2.11E-05 epithelium migration 2.36E-05 response to external stimulus 2.41E-05 head development 3.31E-05 vasculature development 3.55E-05 negative regulation of response to stimulus 4.07E-05 glutathione derivative biosynthetic process 5.07E-05 regulation of neurogenesis 5.92E-05 substrate adhesion-dependent cell spreading 9.36E-05 regulation of anatomical structure morphogenesis 0.000106923 reproductive structure development 0.000107995 cell-cell junction organization 0.000112023 enzyme linked receptor protein signaling pathway 0.000130003 negative regulation of cell-substrate adhesion 0.0001301 heart development 0.0001593 positive regulation of macromolecule metabolic process 0.000165563 regulation of localization 0.000190455 tissue development 0.000210358 epithelial cell differentiation 0.000221245 cell-cell signaling by wnt 0.000231061 positive regulation of binding 0.000255894 negative chemotaxis 0.000278733 cellular response to stimulus 0.000436874 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.000448384 anatomical structure formation involved in morphogenesis 0.000577643 response to interferon-alpha 0.000611196 apoptotic process 0.000625704 gland development 0.000647321 positive regulation of signal transduction 0.000665853 regulation of biological quality 0.000719198 myeloid leukocyte differentiation 0.000729002 cellular response to endogenous stimulus 0.000732773 cellular oxidant detoxification 0.000747519 regulation of protein metabolic process 0.000838487 regulation of phosphorylation 0.000844913 negative regulation of cell communication 0.001027572 negative regulation of signaling 0.001093709 regulation of cell adhesion 0.00115617 response to glucocorticoid 0.001209493 cell death 0.001242417 cellular response to extracellular stimulus 0.001341421 negative regulation of neuron differentiation 0.001341421 detoxification 0.001341799 taxis 0.001453714 cellular response to organic cyclic compound 0.001453714 regulation of cell-matrix adhesion 0.001471997 single-multicellular organism process 0.001475574 cell surface receptor signaling pathway involved in cell-cell signaling 0.0016572 axon development 0.001994389 development of primary sexual characteristics 0.002001984 positive regulation of epithelial cell migration 0.002105511 regulation of phosphorus metabolic process 0.002114058 endoderm development 0.002136441 regulation of B cell differentiation 0.002219841 regulation of response to stress 0.002391935 negative regulation of nervous system development 0.002663099 regulation of DNA binding 0.002718087 pharyngeal system development 0.002760564 glutathione metabolic process 0.002834872 circulatory system development 0.002844064 extracellular matrix organization 0.002865124 negative regulation of cell differentiation 0.003033535 "Wnt signaling pathway, calcium modulating pathway " 0.003147586 regulation of signal transduction 0.003245394 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 0.003397263 male gonad development 0.003824064 adherens junction assembly 0.00382893 cell morphogenesis involved in neuron differentiation 0.00385711 regulation of immune response 0.00388318 secretion 0.004301117 response to steroid hormone 0.004434133 regulation of cell proliferation 0.004907385 positive regulation of cell proliferation 0.004931796 single-organism metabolic process 0.005005 metanephros development 0.005021361 forebrain development 0.005138533 tube development 0.005278931 response to transforming growth factor beta 0.005392475 cell-substrate junction assembly 0.005481005 platelet degranulation 0.005525241 hematopoietic or lymphoid organ development 0.006502402 regulation of Wnt signaling pathway 0.006865777 reverse cholesterol transport 0.007066243 regulation of substrate adhesion-dependent cell spreading 0.007140547 embryonic morphogenesis 0.007296986 cellular response to starvation 0.007388126 midbrain development 0.007680226 actin cytoskeleton organization 0.007918545 biological phase 0.008157673 regulation of cellular response to growth factor stimulus 0.008257576 axon guidance 0.008440164 animal organ morphogenesis 0.008564324 vascular endothelial growth factor receptor signaling pathway 0.009024835 negative regulation of viral entry into host cell 0.009102507 positive regulation of multicellular organismal process 0.00977077 regulation of angiogenesis 0.009974482 focal adhesion assembly 0.01000158 cellular response to corticosteroid stimulus 0.010256032 cellular component organization or biogenesis 0.010389001 ureteric bud development 0.010556309 renal system development 0.010741698 positive regulation of cellular protein metabolic process 0.011182368 mesonephric epithelium development 0.011398051 regulation of adherens junction organization 0.01150252 natural killer cell differentiation 0.011528596 neuron projection morphogenesis 0.012443738 developmental growth involved in morphogenesis 0.01266338 positive regulation of ryanodine-sensitive calcium-release channel activity 0.012868296 regulation of response to external stimulus 0.013488459 male sex differentiation 0.014151543 embryonic hemopoiesis 0.014385128 response to thyroid hormone 0.014385128 stem cell differentiation 0.014637702 synapse organization 0.014642205 signal transduction by protein phosphorylation 0.014705123 morphogenesis of an epithelium 0.015346156 plasma membrane organization 0.015350573 regulation of wound healing 0.015361837 positive regulation of kidney development 0.015465323 negative regulation of cellular process 0.015491878 organic hydroxy compound metabolic process 0.015749937 muscle cell differentiation 0.016333944 response to organic substance 0.016437592 regulation of protein modification process 0.016991387 regulation of cytoskeleton organization 0.017263558 retinal ganglion cell axon guidance 0.017713435 response to interferon-beta 0.017713435 positive regulation of fat cell differentiation 0.017719802 negative regulation of multicellular organismal process 0.017721068 intracellular signal transduction 0.017744871 negative regulation of locomotion 0.01802686 regulation of actin filament bundle assembly 0.018481835 regulation of MAPK cascade 0.018489132 high-density lipoprotein particle assembly 0.019030611 regulation of cell communication by electrical coupling involved in cardiac conduction 0.019030611 regulation of lamellipodium morphogenesis 0.019030611 regulation of programmed cell death 0.020299059 negative regulation of cellular amide metabolic process 0.020702563 protein-lipid complex assembly 0.021555408 tube morphogenesis 0.022051073 developmental cell growth 0.022346317 animal organ development 0.022798187 negative regulation of intracellular signal transduction 0.023206927 exocytosis 0.024342292 positive regulation of cellular component organization 0.02494861 regulation of actin filament-based process 0.025378494 extracellular matrix disassembly 0.025435839 homophilic cell adhesion via plasma membrane adhesion molecules 0.025457172 response to other organism 0.026169754 response to axon injury 0.026284874 negative regulation of ryanodine-sensitive calcium-release channel activity 0.026804078 nephric duct morphogenesis 0.026804078 phosphatidylinositol-mediated signaling 0.026880281 regulation of protein localization 0.02710684 negative regulation of molecular function 0.02728704 regulation of axonogenesis 0.02815242 embryo development 0.029279061 B cell activation 0.029419165 positive regulation of transport 0.029797292 response to growth factor 0.030264104 regulation of cell projection organization 0.030822117 blood coagulation 0.031012447 regulation of cell shape 0.03278297 negative regulation of macromolecule metabolic process 0.03418473 response to nutrient 0.034249676 cell part morphogenesis 0.034434344 negative regulation of cellular biosynthetic process 0.035737614 regulation of biological process 0.03577179 positive regulation of cell migration 0.035874653 L-ascorbic acid metabolic process 0.036337538 negative regulation of epithelial to mesenchymal transition 0.036587757 canonical Wnt signaling pathway 0.038127715 establishment of protein localization to plasma membrane 0.038502878 negative regulation of transcription by transcription factor localization 0.038609642 prostate gland stromal morphogenesis 0.038609642 transforming growth factor beta receptor signaling pathway 0.039500494 cellular response to cytokine stimulus 0.040876541 regulation of cardiac muscle contraction 0.041133493 cell migration 0.041258193 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 0.041760888 regulation of immune effector process 0.042181237 negative regulation of cell morphogenesis involved in differentiation 0.042450888 response to oxygen-containing compound 0.043232832 positive regulation of cell differentiation 0.043392139 entry into host cell 0.04345429 entry into other organism involved in symbiotic interaction 0.04345429 movement of cell or subcellular component 0.043965803 cellular response to lipid 0.046280916 cellular carbohydrate catabolic process 0.04652972 leukocyte activation 0.047631988 3'-UTR-mediated mRNA destabilization 0.047769637 hepatocyte apoptotic process 0.047769637 negative regulation of stem cell differentiation 0.047769637 positive regulation of endothelial cell migration 0.048602049 mesenchyme development 0.048623505 negative regulation of epithelial cell proliferation 0.048814603 negative regulation of cellular protein metabolic process 0.048959978 regulation of hormone metabolic process 0.049958617 --------------------------------------------- "EP #10: 773 cells, 766 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 1, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 1, St5_3_: 1, stage5_: 1, stage6.2_: 1, stage6.7_: 1, stage6.14_: 1, " Top Genes: 2.464 ATP5G1/ENSG00000159199.8 2.036 B2M/ENSG00000166710.12 1.945 COX14/ENSG00000178449.3 1.849 ECH1/ENSG00000104823.4 1.792 NDUFB1/ENSG00000183648.4 1.774 CYB5A/ENSG00000166347.13 1.764 NDUFA7/ENSG00000267855.1 1.705 DBI/ENSG00000155368.12 1.632 LAMTOR4/ENSG00000188186.6 1.617 SCP2/ENSG00000116171.12 1.589 SAT1/ENSG00000130066.12 1.586 HIGD1A/ENSG00000181061.9 1.562 MINOS1/ENSG00000173436.9 1.548 PRDX5/ENSG00000126432.9 1.543 SPCS1/ENSG00000114902.9 1.538 ATRAID/ENSG00000138085.11 1.529 TXN/ENSG00000136810.8 1.523 RP11-6N17.6/ENSG00000264019.1 1.516 UQCRQ/ENSG00000164405.6 1.495 HSPE1/ENSG00000115541.6 1.491 ASAH1/ENSG00000104763.13 1.485 GABARAPL2/ENSG00000034713.3 1.477 TMEM59/ENSG00000116209.7 1.464 TOMM5/ENSG00000175768.8 1.452 SNHG8/ENSG00000269893.1 1.444 TAF9/ENSG00000085231.9 1.443 C1ORF43/ENSG00000143612.14 1.429 ETNK1/ENSG00000139163.11 1.418 CYSTM1/ENSG00000120306.5 1.402 MPC2/ENSG00000143158.6 1.402 CD59/ENSG00000085063.10 1.372 LINC00657/ENSG00000260032.1 1.37 NDUFA1/ENSG00000125356.6 1.365 RP11-622K12.1/ENSG00000204272.6 1.34 RDH11/ENSG00000072042.8 1.336 AC040977.1/ENSG00000269871.1 1.334 PHPT1/ENSG00000054148.13 1.332 PSME2/ENSG00000100911.9 1.326 NDUFA2/ENSG00000131495.4 1.312 ETFB/ENSG00000105379.5 1.308 MRPL33/ENSG00000243147.3 1.284 COX8A/ENSG00000176340.3 1.276 ATP5H/ENSG00000167863.7 1.266 MDH2/ENSG00000146701.6 1.265 REEP5/ENSG00000129625.8 1.257 SDHB/ENSG00000117118.5 1.256 CD46/ENSG00000117335.14 1.247 NDUFC1/ENSG00000109390.7 1.244 UQCR10/ENSG00000184076.10 1.236 VPS25/ENSG00000131475.2 1.231 TMEM208/ENSG00000168701.14 1.215 TMEM14B/ENSG00000137210.8 1.213 LSMD1/ENSG00000183011.9 1.202 ALDOA/ENSG00000149925.12 1.199 MRPL22/ENSG00000082515.12 1.196 FIS1/ENSG00000214253.4 1.186 VMP1/ENSG00000062716.5 1.182 C6ORF48/ENSG00000204387.8 1.173 NAA20/ENSG00000173418.7 1.168 AKR1A1/ENSG00000117448.9 1.157 CD164/ENSG00000135535.10 1.152 NDUFA3/ENSG00000170906.11 1.146 ETFA/ENSG00000140374.11 1.142 COX5B/ENSG00000135940.2 1.142 BSCL2/ENSG00000168000.10 1.141 CISD1/ENSG00000122873.7 1.138 GHITM/ENSG00000165678.15 1.134 NDUFA5/ENSG00000128609.10 1.117 POLR2H/ENSG00000163882.5 1.117 CNIH/ENSG00000100528.7 1.113 NDUFB8/ENSG00000166136.11 1.111 N4BP2L2/ENSG00000244754.4 1.106 ALG5/ENSG00000120697.4 1.105 ATPIF1/ENSG00000130770.13 1.102 PSMF1/ENSG00000125818.12 1.095 PDCD4/ENSG00000150593.11 1.093 NPC2/ENSG00000119655.4 1.093 TRMT112/ENSG00000173113.2 1.091 ANAPC13/ENSG00000129055.8 1.091 ESD/ENSG00000139684.8 1.087 NDUFB3/ENSG00000119013.4 1.086 IER3IP1/ENSG00000134049.3 1.084 NDUFA11/ENSG00000174886.8 1.078 ATP6V1E1/ENSG00000131100.8 1.075 ORMDL2/ENSG00000123353.5 1.075 NDUFS4/ENSG00000164258.7 1.073 DAD1/ENSG00000129562.6 1.072 PDCD5/ENSG00000105185.6 1.066 COA3/ENSG00000183978.7 1.059 PTPLAD1/ENSG00000074696.7 1.055 POLR1D/ENSG00000186184.11 1.053 SCOC/ENSG00000153130.12 1.047 PPA2/ENSG00000138777.15 1.047 "NME1-NME2,NME2/ENSG00000011052.16" 1.046 PEBP1/ENSG00000089220.4 1.044 MRPL36/ENSG00000171421.8 1.033 HADHB/ENSG00000138029.9 1.03 ANAPC11/ENSG00000141552.13 1.03 MRPL51/ENSG00000111639.3 1.027 HRSP12/ENSG00000132541.6 1.02 NDUFV2/ENSG00000178127.8 1.019 SF3B5/ENSG00000169976.5 1.016 NDUFAF2/ENSG00000164182.6 1.013 ZNF706/ENSG00000120963.7 1.01 SOD1/ENSG00000142168.10 1.007 ACOT13/ENSG00000112304.5 1.004 SLC50A1/ENSG00000169241.12 1 COX17/ENSG00000138495.2 0.979 AC073346.2/ENSG00000214194.4 0.979 HSPB11/ENSG00000081870.6 0.977 MIEN1/ENSG00000141741.7 0.976 ARRDC3/ENSG00000113369.4 0.974 OCIAD2/ENSG00000145247.7 0.967 APOC1/ENSG00000130208.5 0.965 NOP10/ENSG00000182117.4 0.963 ARPC5/ENSG00000162704.11 0.962 UFM1/ENSG00000120686.7 0.96 ACAT1/ENSG00000075239.9 0.957 TRAPPC4/ENSG00000196655.5 0.954 TECR/ENSG00000099797.7 0.954 TXNDC12/ENSG00000117862.6 0.952 ROMO1/ENSG00000125995.11 0.944 RPL36AL/ENSG00000165502.6 0.942 RHOA/ENSG00000067560.6 0.941 TMEM256/ENSG00000205544.3 0.939 PRKAR1A/ENSG00000108946.8 0.939 C14ORF2/ENSG00000156411.5 0.938 SH3BGRL/ENSG00000131171.8 0.935 VPS28/ENSG00000160948.9 0.934 RAB1A/ENSG00000138069.12 0.929 CHCHD2/ENSG00000106153.12 0.929 PSMA5/ENSG00000143106.8 0.925 MPV17/ENSG00000115204.9 0.924 PFN2/ENSG00000070087.9 0.921 OXA1L/ENSG00000155463.8 0.919 TMCO1/ENSG00000143183.12 0.919 SRPRB/ENSG00000144867.6 0.916 C11ORF48/ENSG00000162194.8 0.914 NDUFB2/ENSG00000090266.8 0.912 ERO1L/ENSG00000197930.8 0.908 CHURC1/ENSG00000258289.2 0.906 HAX1/ENSG00000143575.10 0.905 CAPNS1/ENSG00000126247.6 0.905 SEC11C/ENSG00000166562.4 0.903 MNF1/ENSG00000137288.4 0.901 ATP6V1A/ENSG00000114573.5 0.9 COA4/ENSG00000181924.6 0.9 REEP3/ENSG00000165476.8 0.9 C7ORF73/ENSG00000243317.3 0.893 ARL6IP5/ENSG00000144746.6 0.89 CLTC/ENSG00000141367.6 0.89 SEC11A/ENSG00000140612.9 0.888 RNA28S5/ENSG00000226958.1 0.887 CDH1/ENSG00000039068.13 0.886 GARS/ENSG00000106105.9 0.884 CDC42BPA/ENSG00000143776.14 0.884 LCLAT1/ENSG00000172954.9 0.884 RPS27L/ENSG00000185088.8 0.88 SLC25A5/ENSG00000005022.5 0.879 POLR2G/ENSG00000168002.7 0.879 TMEM230/ENSG00000089063.10 0.877 SDF2/ENSG00000132581.4 0.877 TMEM205/ENSG00000105518.9 0.875 TMEM14A/ENSG00000096092.5 0.866 NDUFB10/ENSG00000140990.10 0.866 HADHA/ENSG00000084754.6 0.864 SAP18/ENSG00000150459.7 0.862 TMBIM4/ENSG00000155957.12 0.858 COX5A/ENSG00000178741.7 0.858 C18ORF32/ENSG00000177576.6 0.856 PLEKHB2/ENSG00000115762.12 0.855 CDKN1C/ENSG00000129757.8 0.854 RPAIN/ENSG00000129197.10 0.854 RAB2A/ENSG00000104388.10 0.852 NDUFB6/ENSG00000165264.6 0.844 SAR1B/ENSG00000152700.9 0.841 MRPL42/ENSG00000198015.8 0.84 LAMP2/ENSG00000005893.11 0.84 SDHD/ENSG00000204370.4 0.84 ARL1/ENSG00000120805.9 0.833 NDUFB9/ENSG00000147684.3 0.83 ANAPC5/ENSG00000089053.8 0.828 ARL2/ENSG00000213465.3 0.827 CBR4/ENSG00000145439.7 0.825 RAB25/ENSG00000132698.9 0.821 FAM96A/ENSG00000166797.6 0.82 SEC62/ENSG00000008952.12 0.817 TMEM167A/ENSG00000174695.5 0.817 MRPS33/ENSG00000090263.11 0.815 CHMP2A/ENSG00000130724.4 0.811 LIN7C/ENSG00000148943.7 0.811 CHCHD1/ENSG00000172586.7 0.805 ELOVL5/ENSG00000012660.9 0.802 MYEOV2/ENSG00000172428.5 0.802 OAT/ENSG00000065154.7 0.8 AC011933.1/ENSG00000257073.1 0.798 METTL5/ENSG00000138382.9 0.797 GSTK1/ENSG00000197448.9 0.794 ARPC3/ENSG00000111229.11 0.785 ATP6AP2/ENSG00000182220.9 0.785 MTRNR2L12/ENSG00000269028.2 0.784 NDUFAF3/ENSG00000178057.10 0.784 LAMTOR2/ENSG00000116586.7 0.783 VAPA/ENSG00000101558.9 0.782 RAB7A/ENSG00000075785.8 0.779 BNIP3L/ENSG00000104765.10 0.779 GRHPR/ENSG00000137106.12 0.774 ATP5J/ENSG00000154723.8 0.772 HDLBP/ENSG00000115677.12 0.771 TRAP1/ENSG00000126602.6 0.771 PTCD3/ENSG00000132300.14 0.771 HMGCL/ENSG00000117305.10 0.769 C19ORF53/ENSG00000104979.4 0.765 GSTA4/ENSG00000170899.6 0.762 PARK7/ENSG00000116288.8 0.762 GCA/ENSG00000115271.6 0.757 PLIN2/ENSG00000147872.5 0.757 C5ORF15/ENSG00000113583.6 0.754 ATP5G3/ENSG00000154518.5 0.753 NMD3/ENSG00000169251.8 0.75 LAMTOR5/ENSG00000134248.9 0.748 MRPL40/ENSG00000185608.4 0.743 NDUFS8/ENSG00000110717.6 0.742 FAM200B/ENSG00000237765.2 0.742 POLR2L/ENSG00000177700.5 0.741 FAM162A/ENSG00000114023.11 0.74 STX8/ENSG00000170310.8 0.738 XBP1/ENSG00000100219.12 0.737 GGCT/ENSG00000006625.13 0.736 GOLGA7/ENSG00000147533.12 0.736 LINC00493/ENSG00000232388.1 0.731 BCAP31/ENSG00000185825.10 0.728 SDHA/ENSG00000073578.12 0.727 TMEM138/ENSG00000149483.7 0.724 MRPS36/ENSG00000134056.7 0.723 NDUFS3/ENSG00000213619.5 0.722 NDUFA8/ENSG00000119421.5 0.722 UQCRB/ENSG00000156467.5 0.72 ERVK3-1/ENSG00000142396.5 0.719 POLR2F/ENSG00000100142.8 0.717 EI24/ENSG00000149547.10 0.716 ORMDL1/ENSG00000128699.9 0.716 USP15/ENSG00000135655.9 0.713 ATP6V1F/ENSG00000128524.4 0.713 TAGLN2/ENSG00000158710.10 0.711 PIGF/ENSG00000151665.8 0.709 NDUFB11/ENSG00000147123.10 0.707 DHRS7/ENSG00000100612.9 0.706 APOA1BP/ENSG00000163382.7 0.703 COA5/ENSG00000183513.4 0.703 NIT2/ENSG00000114021.6 0.7 SRP19/ENSG00000153037.7 0.694 ECI2/ENSG00000198721.8 0.694 MRPL14/ENSG00000180992.5 0.692 COX15/ENSG00000014919.8 0.692 ARCN1/ENSG00000095139.9 0.692 RNASEK/ENSG00000219200.5 0.692 ITM2B/ENSG00000136156.7 0.691 CMC2/ENSG00000103121.4 0.69 CKLF/ENSG00000217555.7 0.689 NDUFA10/ENSG00000130414.7 0.689 EIF3K/ENSG00000178982.5 0.687 TM9SF2/ENSG00000125304.8 0.686 ID2/ENSG00000115738.5 0.686 HSD17B10/ENSG00000072506.8 0.686 TMEM219/ENSG00000149932.12 0.685 MTCH2/ENSG00000109919.5 0.684 NDUFC2/ENSG00000151366.8 0.683 CMC1/ENSG00000187118.8 0.682 OFD1/ENSG00000046651.10 0.682 COPS6/ENSG00000168090.5 0.678 SMIM11/ENSG00000205670.6 0.672 RAC1/ENSG00000136238.13 0.667 COX11/ENSG00000166260.6 0.667 SETD5-AS1/ENSG00000206573.4 0.667 SBDS/ENSG00000126524.5 0.666 TVP23B/ENSG00000171928.9 0.664 BBIP1/ENSG00000214413.3 0.662 RP11-316M1.12/ENSG00000259357.1 0.66 RNF10/ENSG00000022840.11 0.658 CANX/ENSG00000127022.10 0.656 AC079742.4/ENSG00000232581.1 0.655 LINC00116/ENSG00000175701.6 0.655 HEXA/ENSG00000213614.5 0.652 ATOX1/ENSG00000177556.7 0.651 PFDN2/ENSG00000143256.4 0.651 SNX2/ENSG00000205302.2 0.649 EIF4A3/ENSG00000141543.5 0.648 MRPS18B/ENSG00000204568.7 0.648 RABGGTB/ENSG00000137955.11 0.645 MTHFS/ENSG00000136371.5 0.645 C15ORF40/ENSG00000169609.9 0.644 TMEM60/ENSG00000135211.5 0.641 VPS29/ENSG00000111237.14 0.639 SCAMP3/ENSG00000116521.6 0.638 COX7A2L/ENSG00000115944.9 0.637 MRPL53/ENSG00000204822.6 0.637 SHISA5/ENSG00000164054.11 0.635 ZDHHC4/ENSG00000136247.10 0.635 CNPY2/ENSG00000257727.1 0.635 GPX3/ENSG00000211445.6 0.634 SMIM4/ENSG00000168273.3 0.633 PPIE/ENSG00000084072.12 0.633 CRYZ/ENSG00000116791.9 0.632 TMEM179B/ENSG00000185475.4 0.632 VAMP8/ENSG00000118640.6 0.631 LRRC42/ENSG00000116212.10 0.627 YIPF3/ENSG00000137207.7 0.627 NDUFA9/ENSG00000139180.5 0.625 VAMP3/ENSG00000049245.8 0.624 DPM3/ENSG00000179085.7 0.623 MRPL18/ENSG00000112110.5 0.622 FRA10AC1/ENSG00000148690.10 0.621 TIMM17A/ENSG00000134375.6 0.621 ZNHIT1/ENSG00000106400.7 0.619 SAT2/ENSG00000141504.7 0.615 TALDO1/ENSG00000177156.6 0.612 DAP3/ENSG00000132676.10 0.611 KDELR2/ENSG00000136240.5 0.611 CASP6/ENSG00000138794.5 0.61 DERA/ENSG00000023697.8 0.609 TMEM126B/ENSG00000171204.8 0.609 NDUFV3/ENSG00000160194.12 0.606 SNX3/ENSG00000112335.10 0.605 IFT20/ENSG00000109083.9 0.605 PEMT/ENSG00000133027.13 0.601 SNHG6/ENSG00000245910.3 0.601 SLMO2/ENSG00000101166.11 0.6 MRPL20/ENSG00000242485.1 0.599 CDC26/ENSG00000176386.4 0.599 C14ORF119/ENSG00000179933.4 0.596 SNHG15/ENSG00000232956.3 0.595 GLB1/ENSG00000170266.11 0.593 CTSA/ENSG00000064601.11 0.593 RP11-18I14.10/ENSG00000269609.1 0.593 BECN1/ENSG00000126581.8 0.592 EPCAM/ENSG00000119888.6 0.59 DECR1/ENSG00000104325.2 0.59 NHP2L1/ENSG00000100138.9 0.589 TMEM141/ENSG00000244187.2 0.588 FBXO7/ENSG00000100225.13 0.588 IP6K2/ENSG00000068745.10 0.585 MRPL43/ENSG00000055950.12 0.583 MYL12B/ENSG00000118680.8 0.582 SRA1/ENSG00000213523.5 0.581 BRK1/ENSG00000254999.2 0.581 IDI1/ENSG00000067064.6 0.58 GSTO1/ENSG00000148834.8 0.579 LGMN/ENSG00000100600.10 0.578 CASC4/ENSG00000166734.14 0.577 PGAM1/ENSG00000171314.8 0.576 ISCA1/ENSG00000135070.9 0.572 NDUFA13/ENSG00000186010.12 0.569 MAP3K13/ENSG00000073803.9 0.563 CALM3/ENSG00000160014.12 0.561 LETMD1/ENSG00000050426.10 0.56 SLC39A9/ENSG00000029364.7 0.56 CHMP3/ENSG00000115561.10 0.56 MRPL34/ENSG00000130312.2 0.559 MRPS16/ENSG00000182180.9 0.557 MRPS24/ENSG00000062582.9 0.556 RPL26L1/ENSG00000037241.3 0.555 ATG3/ENSG00000144848.6 0.555 COPB2/ENSG00000184432.4 0.555 RTFDC1/ENSG00000022277.8 0.554 PGRMC2/ENSG00000164040.11 0.549 SRPR/ENSG00000182934.7 0.549 TTC32/ENSG00000183891.5 0.548 CHID1/ENSG00000177830.13 0.546 EEF1E1/ENSG00000124802.7 0.544 CTSL1/ENSG00000135047.10 0.543 PTEN/ENSG00000171862.5 0.541 TM9SF3/ENSG00000077147.10 0.54 RAP1B/ENSG00000127314.13 0.54 RP11-488L18.10/ENSG00000259865.1 0.539 PGK1/ENSG00000102144.9 0.538 GLUD1/ENSG00000148672.7 0.538 COX6B1/ENSG00000126267.4 0.537 CYP51A1/ENSG00000001630.11 0.535 AK2/ENSG00000004455.12 0.534 ZFAND2A/ENSG00000178381.7 0.534 AKAP9/ENSG00000127914.12 0.532 ADD1/ENSG00000087274.12 0.532 JPX/ENSG00000225470.2 0.529 CCNH/ENSG00000134480.9 0.528 TOMM7/ENSG00000196683.6 0.525 BNIP3/ENSG00000176171.7 0.523 TMX1/ENSG00000139921.8 0.523 UQCR11/ENSG00000127540.7 0.521 ALDH9A1/ENSG00000143149.8 0.521 WDR83OS/ENSG00000105583.5 0.519 CCNB1IP1/ENSG00000100814.13 0.518 DDX3Y/ENSG00000067048.12 0.518 C1ORF85/ENSG00000198715.6 0.516 RWDD2B/ENSG00000156253.2 0.513 MED8/ENSG00000159479.12 0.51 CSNK2B/ENSG00000204435.9 0.51 PLA2G16/ENSG00000176485.6 0.509 TIMMDC1/ENSG00000113845.5 0.508 SUPT20H/ENSG00000102710.15 0.508 UCP2/ENSG00000175567.3 0.507 USMG5/ENSG00000173915.8 0.507 TMEM161B-AS1/ENSG00000247828.2 0.507 C10ORF32/ENSG00000166275.11 0.506 NARS/ENSG00000134440.7 0.504 RAB5A/ENSG00000144566.6 0.503 TPD52/ENSG00000076554.11 0.503 MKKS/ENSG00000125863.12 0.502 C1D/ENSG00000197223.7 0.5 BOLA3/ENSG00000163170.7 0.5 LAMTOR3/ENSG00000109270.8 0.499 MTFR1L/ENSG00000117640.13 0.498 COMMD8/ENSG00000169019.9 0.498 ECHDC1/ENSG00000093144.14 0.495 AP1G2/ENSG00000213983.7 0.494 TCF25/ENSG00000141002.13 0.493 CAMLG/ENSG00000164615.3 0.492 HMOX2/ENSG00000103415.7 0.492 AK3/ENSG00000147853.11 0.492 ALG13/ENSG00000101901.6 0.492 TXNL4A/ENSG00000141759.10 0.487 C11ORF54/ENSG00000182919.10 0.487 C1ORF63/ENSG00000117616.13 0.486 FGD5-AS1/ENSG00000225733.1 0.484 TWF1/ENSG00000151239.9 0.482 NECAP1/ENSG00000089818.12 0.481 DYRK4/ENSG00000010219.8 0.48 CRYZL1/ENSG00000205758.7 0.48 EPS15/ENSG00000085832.12 0.479 MCTS1/ENSG00000232119.2 0.479 KPNA2/ENSG00000182481.4 0.479 ATP6V1C1/ENSG00000155097.7 0.477 LEPROTL1/ENSG00000104660.13 0.477 TMED7/ENSG00000134970.13 0.476 COA6/ENSG00000168275.10 0.475 MOCS2/ENSG00000164172.14 0.474 ZCCHC10/ENSG00000155329.7 0.474 NUDC/ENSG00000090273.9 0.472 EMC2/ENSG00000104412.3 0.47 SNHG9/ENSG00000255198.2 0.469 CCNDBP1/ENSG00000166946.9 0.469 COQ9/ENSG00000088682.9 0.468 NCOA4/ENSG00000138293.15 0.468 UBE2L6/ENSG00000156587.11 0.468 UQCRH/ENSG00000173660.7 0.467 RN7SL1/ENSG00000258486.1 0.464 EIF2B5/ENSG00000145191.7 0.464 SETD3/ENSG00000183576.8 0.464 TP53TG1/ENSG00000182165.12 0.462 TIMM9/ENSG00000100575.9 0.462 RBX1/ENSG00000100387.8 0.461 DYNC2LI1/ENSG00000138036.14 0.46 CCDC12/ENSG00000160799.7 0.459 C12ORF73/ENSG00000204954.5 0.457 PHYH/ENSG00000107537.9 0.456 GNG10/ENSG00000242616.3 0.455 PCNP/ENSG00000081154.7 0.454 UBE2V2/ENSG00000169139.7 0.453 BRE/ENSG00000158019.16 0.453 NDUFS7/ENSG00000115286.14 0.452 DDX39A/ENSG00000123136.10 0.451 RP11-113K21.5/ENSG00000246067.2 0.451 TPM1/ENSG00000140416.15 0.45 TM2D3/ENSG00000184277.8 0.448 RPN1/ENSG00000163902.7 0.448 PSAP/ENSG00000197746.9 0.444 SPAG9/ENSG00000008294.16 0.443 TRIM26/ENSG00000234127.4 0.442 C5ORF45/ENSG00000161010.10 0.441 IBTK/ENSG00000005700.10 0.44 CCDC104/ENSG00000163001.7 0.44 CCDC53/ENSG00000120860.6 0.439 MRFAP1L1/ENSG00000178988.10 0.438 ZNF330/ENSG00000109445.6 0.438 PIGP/ENSG00000185808.8 0.437 NEU1/ENSG00000204386.6 0.435 STOML2/ENSG00000165283.11 0.434 PIGT/ENSG00000124155.11 0.434 SUCLG1/ENSG00000163541.7 0.433 DSCR3/ENSG00000157538.9 0.432 TXNIP/ENSG00000117289.7 0.431 NDUFA6/ENSG00000184983.5 0.431 ATP5E/ENSG00000124172.5 0.43 ARFGAP2/ENSG00000149182.10 0.429 PDCD10/ENSG00000114209.10 0.428 DHPS/ENSG00000095059.11 0.427 "HYPK,SERF2/ENSG00000242028.1" 0.427 SIKE1/ENSG00000052723.7 0.427 TM2D1/ENSG00000162604.7 0.426 GTF2B/ENSG00000137947.7 0.426 LSM1/ENSG00000175324.5 0.425 ENOPH1/ENSG00000145293.10 0.424 NPTN/ENSG00000156642.12 0.423 COPA/ENSG00000122218.10 0.422 CLTA/ENSG00000122705.12 0.421 USP47/ENSG00000170242.13 0.419 MAPKAPK5-AS1/ENSG00000234608.2 0.419 ARFIP1/ENSG00000164144.10 0.419 PERP/ENSG00000112378.10 0.419 C2ORF74/ENSG00000237651.2 0.417 ERLEC1/ENSG00000068912.9 0.415 PDLIM5/ENSG00000163110.10 0.414 DYNLT1/ENSG00000146425.6 0.413 SEC22C/ENSG00000093183.9 0.413 ELP6/ENSG00000163832.11 0.412 RAP2C/ENSG00000123728.5 0.412 IFNGR2/ENSG00000159128.10 0.411 HSDL2/ENSG00000119471.10 0.41 SNHG16/ENSG00000163597.9 0.409 SELK/ENSG00000113811.6 0.408 IFI27L1/ENSG00000165948.6 0.408 DGUOK/ENSG00000114956.15 0.407 DNAJB11/ENSG00000090520.6 0.407 DNAJB6/ENSG00000105993.10 0.407 ZNF91/ENSG00000167232.9 0.405 EIF2B2/ENSG00000119718.6 0.403 OTUB1/ENSG00000167770.7 0.402 FASTKD3/ENSG00000124279.7 0.402 GALT/ENSG00000213930.7 0.401 IDH3A/ENSG00000166411.9 0.401 MRPL24/ENSG00000143314.8 0.399 COQ10B/ENSG00000115520.4 0.399 AC107016.1/ENSG00000225410.1 0.398 MORN2/ENSG00000188010.8 0.397 MRPS23/ENSG00000181610.8 0.397 ATXN3/ENSG00000066427.17 0.396 NIPSNAP3A/ENSG00000136783.9 0.396 POLR2C/ENSG00000102978.8 0.395 PDXDC1/ENSG00000179889.14 0.394 CAPZB/ENSG00000077549.13 0.394 TRAPPC12/ENSG00000171853.11 0.393 AASDHPPT/ENSG00000149313.6 0.39 COMMD1/ENSG00000173163.6 0.389 PPIL3/ENSG00000240344.4 0.388 DARS/ENSG00000115866.6 0.386 ID3/ENSG00000117318.8 0.385 MED31/ENSG00000108590.6 0.385 XPNPEP1/ENSG00000108039.13 0.384 IDH3G/ENSG00000067829.13 0.384 CAST/ENSG00000153113.18 0.383 RABGAP1L/ENSG00000152061.17 0.383 VCP/ENSG00000165280.11 0.381 PEPD/ENSG00000124299.8 0.381 RNF13/ENSG00000082996.14 0.38 DEGS1/ENSG00000143753.8 0.38 LYPLA1/ENSG00000120992.13 0.378 RNF34/ENSG00000170633.12 0.377 AC007390.5/ENSG00000218739.4 0.377 ERBB3/ENSG00000065361.10 0.375 NIPSNAP1/ENSG00000184117.7 0.373 FAM204A/ENSG00000165669.9 0.372 MRPS28/ENSG00000147586.4 0.372 TIPRL/ENSG00000143155.8 0.37 ATXN2/ENSG00000204842.9 0.37 PIGS/ENSG00000087111.16 0.37 AMZ2/ENSG00000196704.7 0.37 OCIAD1/ENSG00000109180.10 0.369 HLA-A/ENSG00000206503.7 0.367 POP4/ENSG00000105171.5 0.367 DAZAP2/ENSG00000183283.10 0.366 GMPR2/ENSG00000100938.13 0.366 TANK/ENSG00000136560.9 0.366 TOMM20/ENSG00000173726.6 0.366 SLC3A2/ENSG00000168003.12 0.365 DNPEP/ENSG00000123992.14 0.365 TOMM6/ENSG00000214736.3 0.364 COMMD10/ENSG00000145781.4 0.363 UBE2B/ENSG00000119048.3 0.362 BLOC1S2/ENSG00000196072.7 0.36 CNOT10/ENSG00000182973.14 0.36 PMM1/ENSG00000100417.7 0.359 PDRG1/ENSG00000088356.4 0.358 C2CD5/ENSG00000111731.8 0.358 NDUFS2/ENSG00000158864.8 0.357 FAM92A1/ENSG00000188343.8 0.357 TMED5/ENSG00000117500.8 0.356 TOPORS-AS1/ENSG00000235453.3 0.356 ZNF226/ENSG00000167380.12 0.356 KCTD6/ENSG00000168301.8 0.356 TRAPPC2P1/ENSG00000256060.2 0.355 GLA/ENSG00000102393.4 0.355 ACN9/ENSG00000196636.7 0.353 MPC1/ENSG00000060762.14 0.353 GOLT1B/ENSG00000111711.5 0.351 RP4-594I10.3/ENSG00000264443.1 0.35 ITFG1/ENSG00000129636.8 0.35 ABHD10/ENSG00000144827.4 0.35 SNX13/ENSG00000071189.16 0.349 SERINC3/ENSG00000132824.9 0.349 VPS13A/ENSG00000197969.7 0.348 RP11-349A22.5/ENSG00000257621.3 0.348 APTX/ENSG00000137074.14 0.348 CDC16/ENSG00000130177.10 0.348 SNHG12/ENSG00000197989.8 0.348 SCPEP1/ENSG00000121064.8 0.347 LYRM2/ENSG00000083099.6 0.347 DRAM2/ENSG00000156171.10 0.346 APRT/ENSG00000198931.6 0.344 CALCOCO2/ENSG00000136436.9 0.344 LZIC/ENSG00000162441.7 0.344 GNL3/ENSG00000163938.12 0.343 TOM1L1/ENSG00000141198.9 0.341 B4GALT3/ENSG00000158850.10 0.341 GLT8D1/ENSG00000016864.12 0.341 ITPA/ENSG00000125877.7 0.339 PPP2CB/ENSG00000104695.8 0.339 SCFD1/ENSG00000092108.16 0.339 PCBD1/ENSG00000166228.4 0.338 CCDC47/ENSG00000108588.8 0.337 HIST1H2BK/ENSG00000197903.6 0.337 CMPK1/ENSG00000162368.9 0.337 FAM98A/ENSG00000119812.14 0.336 RBMX2/ENSG00000134597.9 0.334 IFNGR1/ENSG00000027697.8 0.334 TRIQK/ENSG00000205133.7 0.334 MRPS7/ENSG00000125445.6 0.334 TMEM50A/ENSG00000183726.6 0.334 LAMC1/ENSG00000135862.5 0.333 GSTT1/ENSG00000184674.8 0.333 LMAN1/ENSG00000074695.5 0.333 TMEM126A/ENSG00000171202.2 0.332 ZFAND1/ENSG00000104231.6 0.331 NDUFS1/ENSG00000023228.8 0.331 TMEM98/ENSG00000006042.7 0.331 PLS1/ENSG00000120756.8 0.331 LYRM5/ENSG00000205707.5 0.331 DDX24/ENSG00000089737.11 0.33 DDT/ENSG00000099977.9 0.33 UBE2G2/ENSG00000184787.14 0.33 CTD-2003C8.1/ENSG00000247271.2 0.33 ACO2/ENSG00000100412.11 0.327 GALK2/ENSG00000156958.10 0.327 AKTIP/ENSG00000166971.11 0.327 ERCC1/ENSG00000012061.11 0.327 FAM127A/ENSG00000134590.9 0.325 SS18L2/ENSG00000008324.6 0.325 PHKB/ENSG00000102893.11 0.325 CRHR1-IT1/ENSG00000204650.9 0.324 TIMM10/ENSG00000134809.4 0.323 LSM10/ENSG00000181817.5 0.323 PHKG2/ENSG00000156873.11 0.322 NABP2/ENSG00000139579.8 0.322 DCAF7/ENSG00000136485.9 0.321 SCAMP2/ENSG00000140497.12 0.32 PTGES3/ENSG00000110958.11 0.32 NDUFB5/ENSG00000136521.8 0.319 RNF14/ENSG00000013561.13 0.319 MCEE/ENSG00000124370.6 0.319 MLX/ENSG00000108788.7 0.318 RP11-220I1.1/ENSG00000233137.2 0.318 GRSF1/ENSG00000132463.9 0.317 LYRM1/ENSG00000102897.5 0.316 CCPG1/ENSG00000260916.1 0.316 GOT2/ENSG00000125166.8 0.314 PSMD4/ENSG00000159352.10 0.311 AIFM1/ENSG00000156709.9 0.311 LRRC28/ENSG00000168904.10 0.311 FBXL5/ENSG00000118564.10 0.311 PFKM/ENSG00000152556.11 0.31 RP11-11N9.4/ENSG00000247134.2 0.31 RWDD1/ENSG00000111832.8 0.307 GFM1/ENSG00000168827.10 0.307 DEF8/ENSG00000140995.12 0.307 SLC39A7/ENSG00000112473.12 0.306 AIG1/ENSG00000146416.12 0.305 CKS1B/ENSG00000173207.8 0.305 ERI3/ENSG00000117419.10 0.304 MAGEH1/ENSG00000187601.3 0.303 SCRN3/ENSG00000144306.9 0.303 SLU7/ENSG00000164609.5 0.303 TCAIM/ENSG00000179152.14 0.302 GSTO2/ENSG00000065621.9 0.302 SLC35A1/ENSG00000164414.12 0.301 SCARB2/ENSG00000138760.4 0.301 ZCCHC17/ENSG00000121766.10 0.3 SNAPC5/ENSG00000174446.7 0.3 ME2/ENSG00000082212.7 0.299 RBP1/ENSG00000114115.5 0.298 HTATIP2/ENSG00000109854.9 0.298 MRPL54/ENSG00000183617.4 0.295 CD63/ENSG00000135404.7 0.294 RNF6/ENSG00000127870.12 0.294 PEF1/ENSG00000162517.8 0.294 METTL23/ENSG00000181038.9 0.293 SFXN4/ENSG00000183605.12 0.293 GOLM1/ENSG00000135052.12 0.293 MAL2/ENSG00000147676.9 0.292 PLIN3/ENSG00000105355.4 0.291 TES/ENSG00000135269.13 0.291 SOD2/ENSG00000112096.11 0.291 POP5/ENSG00000167272.6 0.29 EPHX2/ENSG00000120915.9 0.289 C22ORF28/ENSG00000100220.7 0.288 ACYP1/ENSG00000119640.4 0.288 RP4-717I23.3/ENSG00000223745.3 0.287 OBFC1/ENSG00000107960.6 0.286 SNHG5/ENSG00000203875.5 0.286 NUDCD2/ENSG00000170584.5 0.285 BRD7/ENSG00000166164.11 0.285 MRPS15/ENSG00000116898.7 0.284 KLF13/ENSG00000169926.5 0.284 TMEM80/ENSG00000177042.9 0.283 PAAF1/ENSG00000175575.8 0.282 ANKRD46/ENSG00000186106.7 0.282 RNF113A/ENSG00000125352.4 0.281 LINC00467/ENSG00000153363.8 0.281 DPAGT1/ENSG00000172269.12 0.281 PHLDB2/ENSG00000144824.15 0.28 MGST2/ENSG00000085871.4 0.278 EMC7/ENSG00000134153.5 0.278 RSBN1L-AS1/ENSG00000214293.4 0.278 AP3D1/ENSG00000065000.11 0.278 ACSL3/ENSG00000123983.9 0.277 CHKB/ENSG00000100288.15 0.277 BTD/ENSG00000169814.8 0.277 PTBP3/ENSG00000119314.11 0.276 BTG1/ENSG00000133639.3 0.276 TTC19/ENSG00000011295.10 0.276 CHCHD7/ENSG00000170791.13 0.276 ACADVL/ENSG00000072778.15 0.275 SNRNP35/ENSG00000184209.14 0.275 MMAB/ENSG00000139428.6 0.274 HSPA9/ENSG00000113013.8 0.273 UQCRFS1/ENSG00000169021.4 0.273 ATXN7L3B/ENSG00000253719.2 0.273 PREB/ENSG00000138073.9 0.273 KRTCAP2/ENSG00000163463.6 0.273 TMEM135/ENSG00000166575.12 0.272 DNM1L/ENSG00000087470.13 0.272 TERF2/ENSG00000132604.5 0.27 ZNF561/ENSG00000171469.6 0.27 OSGEP/ENSG00000092094.6 0.27 UGGT2/ENSG00000102595.14 0.268 SPCS3/ENSG00000129128.8 0.266 STARD4/ENSG00000164211.8 0.266 GTF3A/ENSG00000122034.8 0.266 SUMF2/ENSG00000129103.13 0.264 FAM188A/ENSG00000148481.9 0.264 RANGRF/ENSG00000108961.9 0.262 COX10/ENSG00000006695.6 0.262 YIF1A/ENSG00000174851.10 0.261 DCTN3/ENSG00000137100.11 0.261 ACBD3/ENSG00000182827.8 0.26 EMC3/ENSG00000125037.8 0.259 NDUFB4/ENSG00000065518.7 0.259 COASY/ENSG00000068120.10 0.259 ZC3H7A/ENSG00000122299.7 0.259 UBE2T/ENSG00000077152.5 0.258 UBAC2/ENSG00000134882.11 0.258 C10ORF118/ENSG00000165813.12 0.258 EIF3J/ENSG00000104131.8 0.258 PNP/ENSG00000198805.7 0.256 TMEM120A/ENSG00000189077.6 0.256 CNOT4/ENSG00000080802.14 0.255 PEX11B/ENSG00000131779.6 0.255 RABGGTA/ENSG00000100949.10 0.255 SSX2IP/ENSG00000117155.12 0.255 LIPA/ENSG00000107798.13 0.254 MTUS1/ENSG00000129422.9 0.254 KIAA0907/ENSG00000132680.6 0.253 DLEU1/ENSG00000176124.7 0.253 EIF3A/ENSG00000107581.7 0.251 LGALS3BP/ENSG00000108679.7 0.251 APPL2/ENSG00000136044.7 0.251 TRAPPC2L/ENSG00000167515.6 0.25 TXNDC5/ENSG00000239264.3 Overrepresented GO terms in EP #10: Term Pvalue ATP synthesis coupled electron transport 9.44E-43 energy derivation by oxidation of organic compounds 1.26E-37 mitochondrial respiratory chain complex I assembly 1.56E-34 "mitochondrial electron transport, NADH to ubiquinone " 1.04E-33 purine nucleoside triphosphate metabolic process 2.53E-31 ribonucleoside triphosphate metabolic process 4.11E-31 mitochondrion organization 1.02E-30 ATP metabolic process 1.37E-29 ribonucleoside monophosphate metabolic process 7.55E-28 purine nucleoside monophosphate metabolic process 7.86E-28 purine nucleoside metabolic process 2.02E-26 ribonucleoside metabolic process 8.03E-26 glycosyl compound metabolic process 2.36E-25 purine nucleotide metabolic process 1.35E-20 nucleoside phosphate metabolic process 1.41E-20 ribonucleotide metabolic process 6.73E-20 small molecule metabolic process 8.27E-20 protein complex subunit organization 2.73E-17 organonitrogen compound metabolic process 2.79E-16 mitochondrial translational elongation 1.23E-15 mitochondrial translational termination 2.65E-14 cellular protein complex assembly 1.99E-11 protein complex biogenesis 8.66E-11 macromolecular complex assembly 1.69E-10 hydrogen transport 2.33E-10 cellular protein complex disassembly 6.01E-09 organonitrogen compound biosynthetic process 1.19E-08 hydrogen ion transmembrane transport 3.69E-08 macromolecular complex disassembly 1.25E-07 establishment of localization in cell 1.50E-06 peptide metabolic process 3.02E-06 translation 4.32E-06 oxoacid metabolic process 5.53E-06 amide biosynthetic process 7.73E-06 macroautophagy 7.86E-06 response to endoplasmic reticulum stress 3.12E-05 respiratory chain complex IV assembly 3.42E-05 ER to Golgi vesicle-mediated transport 3.60E-05 protein transport 4.75E-05 metabolic process 7.01E-05 "mitochondrial electron transport, cytochrome c to oxygen " 8.18E-05 mitochondrial transport 9.45E-05 aerobic respiration 0.000196406 mitochondrial ATP synthesis coupled proton transport 0.000210786 protein homotetramerization 0.000297914 protein folding 0.000438739 glutathione derivative biosynthetic process 0.000475857 "mitochondrial electron transport, ubiquinol to cytochrome c " 0.000521848 purine nucleoside monophosphate biosynthetic process 0.000967181 purine nucleoside biosynthetic process 0.000979583 small molecule biosynthetic process 0.001120943 ribonucleoside monophosphate biosynthetic process 0.001155664 cellular component organization 0.001248666 ATP biosynthetic process 0.002279931 ribonucleoside biosynthetic process 0.002291513 single-organism catabolic process 0.002355587 "energy coupled proton transport, down electrochemical gradient " 0.002440949 coenzyme metabolic process 0.002487144 oxidation-reduction process 0.002815082 macromolecule localization 0.002880095 tricarboxylic acid cycle 0.004180576 protein K11-linked ubiquitination 0.004180576 cofactor biosynthetic process 0.006205164 dicarboxylic acid metabolic process 0.006556601 cellular protein localization 0.006924979 cytochrome complex assembly 0.007360886 glycosyl compound biosynthetic process 0.00766129 mitochondrial respiratory chain complex III assembly 0.007685365 mitochondrial fragmentation involved in apoptotic process 0.007685365 respiratory electron transport chain 0.008184997 mitophagy 0.00829741 protein N-linked glycosylation via asparagine 0.009689164 regulation of protein catabolic process 0.009925926 protein import into mitochondrial inner membrane 0.011320556 regulation of ubiquitin-specific protease activity 0.011320556 membrane budding 0.01644213 purine nucleoside triphosphate biosynthetic process 0.017096996 monocarboxylic acid catabolic process 0.018087403 organelle disassembly 0.018087403 phosphorus metabolic process 0.018365885 glutathione metabolic process 0.019669068 mitochondrial membrane organization 0.021806193 single-organism process 0.024055441 positive regulation of cellular protein catabolic process 0.024902076 7-methylguanosine RNA capping 0.027988803 glycolipid metabolic process 0.028558804 regulation of autophagy 0.03152528 cellular catabolic process 0.032600958 L-ascorbic acid metabolic process 0.032635022 ribonucleoside triphosphate biosynthetic process 0.033322786 transcription-coupled nucleotide-excision repair 0.033464172 fatty acid beta-oxidation 0.033464172 intracellular protein transmembrane transport 0.035038563 organic acid catabolic process 0.03551674 positive regulation of organelle organization 0.036115797 organic substance catabolic process 0.038781341 antigen processing and presentation of exogenous antigen 0.044214386 carboxylic acid biosynthetic process 0.045265741 protein exit from endoplasmic reticulum 0.046076495 cytosolic transport 0.047306168 organophosphate biosynthetic process 0.047306804 protein targeting to vacuole 0.04732135 --------------------------------------------- "EP #11: 128 cells, 220 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0476190476190476, stage2_: 0.0294117647058824, stage3_: 0.271428571428571, St4_3_: 0.275862068965517, stage4: 0.3, St5_3_: 0.232876712328767, stage5_: 0.09375, stage6.2_: 0.109756097560976, stage6.7_: 0.25, stage6.14_: 0.119402985074627, " Top Genes: 2.292 ANXA3/ENSG00000138772.8 2.112 TAGLN/ENSG00000149591.12 1.705 ANXA2/ENSG00000182718.11 1.495 KRT18/ENSG00000111057.6 1.391 TPM1/ENSG00000140416.15 1.347 CALD1/ENSG00000122786.15 1.338 ANKRD1/ENSG00000148677.6 1.306 EZR/ENSG00000092820.13 1.304 TAGLN2/ENSG00000158710.10 1.265 C12ORF75/ENSG00000235162.4 1.232 AC107016.1/ENSG00000225410.1 1.205 TPM4/ENSG00000167460.10 1.182 KRT8/ENSG00000170421.7 1.135 AC011558.5/ENSG00000267020.1 1.002 VCL/ENSG00000035403.12 0.988 ACTA1/ENSG00000143632.10 0.983 PDLIM1/ENSG00000107438.4 0.981 CNN3/ENSG00000117519.11 0.967 ILK/ENSG00000166333.9 0.918 ATF4/ENSG00000128272.10 0.912 RHOC/ENSG00000155366.11 0.903 FDFT1/ENSG00000079459.8 0.897 CNN2/ENSG00000064666.9 0.889 SDC4/ENSG00000124145.5 0.873 UBD/ENSG00000213886.3 0.871 SKIL/ENSG00000136603.9 0.869 LITAF/ENSG00000189067.8 0.841 MSMO1/ENSG00000052802.8 0.837 TAX1BP3/ENSG00000213977.3 0.831 ITGAV/ENSG00000138448.7 0.83 VIM/ENSG00000026025.9 0.818 PLK2/ENSG00000145632.10 0.815 RP11-244F12.2/ENSG00000259627.1 0.804 RP11-161H23.5/ENSG00000258232.2 0.791 CSRP1/ENSG00000159176.9 0.769 B2M/ENSG00000166710.12 0.764 HMGCS1/ENSG00000112972.10 0.758 DDAH1/ENSG00000153904.14 0.742 LIMA1/ENSG00000050405.9 0.733 TPM2/ENSG00000198467.8 0.726 GPR126/ENSG00000112414.10 0.718 MYH10/ENSG00000133026.8 0.713 NPPB/ENSG00000120937.8 0.71 NABP1/ENSG00000173559.7 0.71 LDLR/ENSG00000130164.7 0.703 CXCL1/ENSG00000163739.4 0.701 ARPC5/ENSG00000162704.11 0.696 KLF6/ENSG00000067082.10 0.681 LPP/ENSG00000145012.8 0.68 F3/ENSG00000117525.9 0.678 QKI/ENSG00000112531.12 0.673 MYL12A/ENSG00000101608.6 0.672 CYP51A1/ENSG00000001630.11 0.668 RDX/ENSG00000137710.10 0.663 DTNA/ENSG00000134769.17 0.662 SLC12A2/ENSG00000064651.9 0.651 TNFRSF12A/ENSG00000006327.9 0.651 PLS3/ENSG00000102024.11 0.646 RP5-1085F17.3/ENSG00000260257.1 0.644 IDI1/ENSG00000067064.6 0.616 MYL12B/ENSG00000118680.8 0.616 MTHFD2/ENSG00000065911.7 0.614 FLNB/ENSG00000136068.10 0.612 PPFIBP2/ENSG00000166387.7 0.609 SPARC/ENSG00000113140.6 0.607 SDCBP/ENSG00000137575.7 0.59 RND3/ENSG00000115963.9 0.587 SC5D/ENSG00000109929.5 0.587 RP3-363L9.1/ENSG00000227064.1 0.577 WEE1/ENSG00000166483.6 0.575 RP11-16E23.4/ENSG00000259924.1 0.574 CYSTM1/ENSG00000120306.5 0.572 TMSB4XP8/ENSG00000187653.10 0.569 PDE3A/ENSG00000172572.6 0.562 SBDS/ENSG00000126524.5 0.562 ENC1/ENSG00000171617.9 0.56 COTL1/ENSG00000103187.5 0.559 RAB11FIP1/ENSG00000156675.11 0.557 IL32/ENSG00000008517.12 0.539 JAG1/ENSG00000101384.7 0.538 DSTN/ENSG00000125868.10 0.536 ACTR3/ENSG00000115091.7 0.534 CAP1/ENSG00000131236.12 0.528 SVIL/ENSG00000197321.10 0.526 FAM107B/ENSG00000065809.9 0.526 FZD5/ENSG00000163251.3 0.524 TJP1/ENSG00000104067.12 0.523 CORO1C/ENSG00000110880.6 0.521 REXO2/ENSG00000076043.5 0.518 ANXA4/ENSG00000196975.9 0.515 IQGAP1/ENSG00000140575.8 0.505 THBS1/ENSG00000137801.9 0.505 UGCG/ENSG00000148154.5 0.502 SMS/ENSG00000102172.11 0.497 CGA/ENSG00000135346.4 0.494 IL6ST/ENSG00000134352.15 0.49 ACTN4/ENSG00000130402.7 0.488 MYADM/ENSG00000179820.11 0.485 PARD6B/ENSG00000124171.4 0.483 VMP1/ENSG00000062716.5 0.481 MYOF/ENSG00000138119.12 0.472 AC093673.5/ENSG00000232533.1 0.471 ZYX/ENSG00000159840.11 0.471 ACTC1/ENSG00000159251.6 0.469 F11R/ENSG00000158769.12 0.466 NFKBIA/ENSG00000100906.6 0.463 PHACTR2/ENSG00000112419.10 0.461 TES/ENSG00000135269.13 0.457 RAP1B/ENSG00000127314.13 0.456 PICALM/ENSG00000073921.13 0.454 S100A10/ENSG00000197747.4 0.454 CCNYL1/ENSG00000163249.5 0.451 STX7/ENSG00000079950.8 0.446 OPTN/ENSG00000123240.12 0.441 ERRFI1/ENSG00000116285.8 0.44 ELOVL5/ENSG00000012660.9 0.439 RTN4/ENSG00000115310.13 0.436 ELMSAN1/ENSG00000156030.8 0.434 RSU1/ENSG00000148484.13 0.434 TUBB6/ENSG00000176014.8 0.431 S100A11/ENSG00000163191.5 0.431 SPTBN1/ENSG00000115306.11 0.425 KIAA1551/ENSG00000174718.7 0.424 PALLD/ENSG00000129116.13 0.423 ANXA5/ENSG00000164111.10 0.422 MYL7/ENSG00000106631.4 0.413 CLIC1/ENSG00000213719.4 0.408 UGP2/ENSG00000169764.10 0.407 MAP1LC3B/ENSG00000140941.8 0.405 ZCCHC10/ENSG00000155329.7 0.401 SULF2/ENSG00000196562.10 0.4 NEDD9/ENSG00000111859.12 0.397 PRPS2/ENSG00000101911.8 0.396 NPC1/ENSG00000141458.7 0.392 AJUBA/ENSG00000129474.11 0.389 RP5-977B1.11/ENSG00000259716.1 0.387 RP4-564F22.2/ENSG00000196756.6 0.387 PSTPIP2/ENSG00000152229.14 0.384 SOCS2/ENSG00000120833.9 0.382 KRT19/ENSG00000171345.9 0.379 CLIC4/ENSG00000169504.10 0.379 FLRT3/ENSG00000125848.9 0.378 ABRACL/ENSG00000146386.7 0.378 TUBA1C/ENSG00000167553.10 0.376 TPM3/ENSG00000143549.14 0.374 TGIF1/ENSG00000177426.15 0.373 RAPGEF2/ENSG00000109756.4 0.368 CREB3/ENSG00000107175.6 0.368 TUFT1/ENSG00000143367.11 0.364 CAPG/ENSG00000042493.11 0.364 ITGB1/ENSG00000150093.14 0.359 JUND/ENSG00000130522.4 0.357 TNFRSF9/ENSG00000049249.4 0.356 NEDD4L/ENSG00000049759.12 0.35 FAM76A/ENSG00000009780.11 0.349 ACAT2/ENSG00000120437.7 0.347 BMP2/ENSG00000125845.6 0.346 MYH9/ENSG00000100345.16 0.345 PROM1/ENSG00000007062.7 0.342 B3GNT7/ENSG00000156966.6 0.341 RP11-14N7.2/ENSG00000232527.3 0.339 PRSS23/ENSG00000150687.7 0.338 DIAPH1/ENSG00000131504.11 0.336 ACOT7/ENSG00000097021.14 0.336 LAMB2/ENSG00000172037.9 0.334 ASPH/ENSG00000198363.11 0.332 S100A6/ENSG00000197956.5 0.332 CXADR/ENSG00000154639.14 0.33 TLN1/ENSG00000137076.14 0.329 TOMM34/ENSG00000025772.7 0.329 LRRC1/ENSG00000137269.10 0.329 RNF19A/ENSG00000034677.7 0.326 RBPMS/ENSG00000157110.11 0.325 YBX3/ENSG00000060138.8 0.322 KDM6A/ENSG00000147050.10 0.321 TNFRSF21/ENSG00000146072.6 0.321 GJA1/ENSG00000152661.7 0.316 ADAM9/ENSG00000168615.7 0.315 TANC1/ENSG00000115183.9 0.315 NUAK1/ENSG00000074590.9 0.314 PCSK7/ENSG00000160613.8 0.313 KLHL5/ENSG00000109790.12 0.312 VAMP8/ENSG00000118640.6 0.312 DYNLT3/ENSG00000165169.6 0.311 CTTN/ENSG00000085733.11 0.306 STK38L/ENSG00000211455.3 0.305 LINC00152/ENSG00000222041.6 0.305 AC068491.1/ENSG00000172965.8 0.305 EDN1/ENSG00000078401.6 0.305 SPATS2L/ENSG00000196141.7 0.303 ID1/ENSG00000125968.7 0.301 DUSP3/ENSG00000108861.4 0.301 WWC2/ENSG00000151718.11 0.297 CTGF/ENSG00000118523.5 0.293 RASSF1/ENSG00000068028.13 0.292 CNN1/ENSG00000130176.3 0.292 CLIP1/ENSG00000130779.15 0.288 DDX39A/ENSG00000123136.10 0.286 RAI14/ENSG00000039560.9 0.285 SWAP70/ENSG00000133789.10 0.285 SPTAN1/ENSG00000197694.9 0.285 TXNDC9/ENSG00000115514.7 0.284 KIAA1033/ENSG00000136051.9 0.283 CARS/ENSG00000110619.12 0.28 TNFAIP1/ENSG00000109079.5 0.277 RAB9A/ENSG00000123595.5 0.277 STX3/ENSG00000166900.10 0.274 ELOVL1/ENSG00000066322.8 0.272 AMOTL2/ENSG00000114019.10 0.266 NEAT1/ENSG00000245532.3 0.264 CKB/ENSG00000166165.8 0.264 HSPB8/ENSG00000152137.2 0.258 TIMP3/ENSG00000100234.11 0.256 FAM114A1/ENSG00000197712.7 0.255 B4GALT1/ENSG00000086062.8 0.255 PAPD4/ENSG00000164329.9 0.255 LTBP1/ENSG00000049323.11 0.255 TOR1AIP2/ENSG00000169905.7 0.252 XRCC4/ENSG00000152422.11 0.252 FHL2/ENSG00000115641.13 Overrepresented GO terms in EP #11: Term Pvalue localization of cell 1.49E-11 cell-cell adhesion 2.68E-09 movement of cell or subcellular component 6.06E-09 cell-cell junction organization 1.45E-08 actin filament organization 3.68E-07 epithelium development 9.78E-07 cell projection organization 1.04E-06 positive regulation of locomotion 1.19E-06 regulation of cell motility 1.89E-06 positive regulation of cell migration 2.17E-06 actomyosin structure organization 2.76E-06 locomotion 2.83E-06 epithelial cell development 3.98E-06 positive regulation of cellular component movement 5.48E-06 organelle organization 7.39E-06 endothelial cell differentiation 7.62E-06 cell junction assembly 8.10E-06 muscle contraction 9.02E-06 regulation of cell junction assembly 1.04E-05 cardiovascular system development 1.58E-05 cellular component organization or biogenesis 1.98E-05 muscle filament sliding 2.02E-05 actin polymerization or depolymerization 2.16E-05 blood vessel development 2.43E-05 positive regulation of multicellular organismal process 2.55E-05 system process 2.61E-05 response to growth factor 3.43E-05 cell migration 3.83E-05 neuron projection morphogenesis 4.24E-05 muscle cell differentiation 4.51E-05 signal transduction 5.51E-05 establishment of protein localization to plasma membrane 5.77E-05 sarcomere organization 8.05E-05 cellular response to organic substance 9.58E-05 in utero embryonic development 0.000101578 actin-mediated cell contraction 0.000112441 angiogenesis 0.000118996 actin filament bundle assembly 0.000135824 cell adhesion 0.000174427 regulation of anatomical structure size 0.000182463 platelet aggregation 0.000182888 regulation of actin filament length 0.000224267 exocytosis 0.000263262 positive regulation of osteoblast differentiation 0.000341846 integrin-mediated signaling pathway 0.000532227 positive regulation of developmental process 0.000545173 Rap protein signal transduction 0.000690689 single-organism developmental process 0.000758271 cell-matrix adhesion 0.000779902 cell development 0.00083781 developmental cell growth 0.000881555 positive regulation of actin filament bundle assembly 0.000936563 cell-substrate adherens junction assembly 0.001006037 plasma membrane organization 0.001089676 negative regulation of transport 0.001209075 regulation of protein depolymerization 0.00122066 secretion 0.001318361 cholesterol biosynthetic process 0.001539016 regulation of apoptotic process 0.001552763 establishment of endothelial intestinal barrier 0.001584298 endocytosis 0.001758014 wound healing 0.001795533 response to stress 0.001862272 cell morphogenesis involved in neuron differentiation 0.001979135 response to abiotic stimulus 0.002148564 negative regulation of intracellular signal transduction 0.002182674 renal filtration cell differentiation 0.002205752 cellular component morphogenesis 0.002237996 actin cytoskeleton organization 0.002466106 positive regulation of response to stimulus 0.002519265 response to external stimulus 0.002655016 cellular response to transforming growth factor beta stimulus 0.002798581 membrane raft organization 0.002806766 glomerular epithelial cell differentiation 0.002806766 cardiocyte differentiation 0.002875744 cardiac muscle tissue development 0.003135991 growth 0.003200771 nervous system development 0.003310769 cell part morphogenesis 0.003459781 programmed cell death 0.003602013 regulation of protein localization 0.003642828 regulation of actin cytoskeleton organization 0.003669597 muscle tissue development 0.003868939 protein localization to cell periphery 0.004051208 regulation of cell differentiation 0.004394699 negative regulation of protein complex disassembly 0.004445167 regulation of multicellular organismal development 0.004603186 axon development 0.005111779 cell activation 0.005329566 transmembrane receptor protein serine/threonine kinase signaling pathway 0.005459829 regulation of protein localization to cell periphery 0.0058693 regulation of cell proliferation 0.005943978 secondary alcohol metabolic process 0.006097568 ossification 0.006201549 protein localization to membrane 0.00621211 negative regulation of interleukin-10 secretion 0.006242305 "substrate-dependent cell migration, cell extension " 0.006461748 regulation of neuron projection development 0.007045269 animal organ development 0.007523806 actin filament-based process 0.007836756 embryo development ending in birth or egg hatching 0.008080025 signaling 0.008144363 response to lipopolysaccharide 0.008469439 tissue morphogenesis 0.008569095 establishment or maintenance of cell polarity 0.008595597 striated muscle cell development 0.008679804 response to chemical 0.008915367 cytoskeletal anchoring at plasma membrane 0.00914138 cell-cell adhesion mediated by integrin 0.00914138 developmental growth involved in morphogenesis 0.009252069 response to tumor necrosis factor 0.009452902 sterol metabolic process 0.010101528 single-organism localization 0.01037297 anatomical structure development 0.010766704 bicellular tight junction assembly 0.010914335 negative regulation of multicellular organismal process 0.011216335 regulation of plasma membrane organization 0.011472113 response to bacterium 0.011769098 regulation of focal adhesion assembly 0.01341395 regulation of cell-substrate adhesion 0.013577816 biological regulation 0.013589583 regulation of actin filament polymerization 0.015264129 platelet degranulation 0.015377063 regulation of cell morphogenesis involved in differentiation 0.015567722 glomerular visceral epithelial cell development 0.016435415 stress fiber assembly 0.016684107 positive regulation of cell development 0.017225839 axon extension 0.017278106 negative regulation of actin filament depolymerization 0.017901452 viral entry into host cell 0.018296454 response to calcium ion 0.018296454 regulation of localization 0.018611027 cell morphogenesis 0.018903644 epithelial cell morphogenesis 0.019446561 response to endogenous stimulus 0.019542734 generation of neurons 0.019586348 establishment of endothelial barrier 0.020989132 transepithelial transport 0.021158833 multicellular organism development 0.021582695 heart morphogenesis 0.021627236 response to inorganic substance 0.021963007 substrate adhesion-dependent cell spreading 0.02205007 negative regulation of developmental process 0.022637364 negative regulation of cell communication 0.022795918 entry into host 0.022858274 entry into cell of other organism involved in symbiotic interaction 0.022858274 positive regulation of organelle organization 0.023107773 receptor metabolic process 0.023446417 glomerulus development 0.023541042 cardiac muscle cell development 0.023541042 negative regulation of signaling 0.023781697 regulation of cellular component biogenesis 0.024363344 single-organism cellular process 0.025786058 regulation of body fluid levels 0.0271367 cellular macromolecule localization 0.02779166 regulation of neurogenesis 0.028256702 ameboidal-type cell migration 0.028589382 blood coagulation 0.029410562 negative regulation of cell death 0.029641264 regulation of cell morphogenesis 0.029748653 positive regulation of intracellular signal transduction 0.032173792 positive regulation of protein localization to plasma membrane 0.036066804 negative regulation of secretion by cell 0.0363547 response to organic cyclic compound 0.036616203 mesenchyme migration 0.036804401 positive regulation of protein localization to early endosome 0.036804401 positive regulation of extracellular exosome assembly 0.036804401 negative regulation of metalloendopeptidase activity 0.036804401 organic hydroxy compound biosynthetic process 0.037908172 multi-organism process 0.038054352 cellular response to metal ion 0.038266876 negative regulation of cell adhesion 0.038398358 microvillus assembly 0.040237649 cellular response to platelet-derived growth factor stimulus 0.040237649 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.040237649 negative regulation of adherens junction organization 0.040237649 hippo signaling 0.040304199 single organismal cell-cell adhesion 0.040603921 keratinocyte differentiation 0.041350823 actin filament capping 0.044878774 response to cAMP 0.046413404 negative regulation of protein polymerization 0.048241356 negative regulation of receptor-mediated endocytosis 0.048387342 response to lipoprotein particle 0.048387342 positive regulation of cell-matrix adhesion 0.049804526 --------------------------------------------- "EP #12: 190 cells, 189 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.714285714285714, St4_3_: 0.436781609195402, stage4: 0.114285714285714, St5_3_: 0.219178082191781, stage5_: 0.390625, stage6.2_: 0.378048780487805, stage6.7_: 0.144736842105263, stage6.14_: 0.164179104477612, " Top Genes: 1.944 PIFO/ENSG00000173947.9 1.795 C1ORF192/ENSG00000188931.3 1.53 C1ORF194/ENSG00000179902.8 1.295 RGS2/ENSG00000116741.6 1.254 CAPSL/ENSG00000152611.7 1.221 MORN2/ENSG00000188010.8 1.169 MLF1/ENSG00000178053.13 1.069 FAM183A/ENSG00000186973.6 1.048 EFHC1/ENSG00000096093.9 1.045 ARMC3/ENSG00000165309.9 1.042 TCTEX1D1/ENSG00000152760.4 0.993 SPAG6/ENSG00000077327.11 0.963 TPPP3/ENSG00000159713.6 0.958 OSCP1/ENSG00000116885.14 0.939 RABL5/ENSG00000128581.11 0.891 C9ORF24/ENSG00000164972.8 0.814 FAM229B/ENSG00000203778.3 0.796 UCP2/ENSG00000175567.3 0.779 CETN2/ENSG00000147400.8 0.757 CC2D2A/ENSG00000048342.11 0.744 NEK11/ENSG00000114670.9 0.707 C6ORF118/ENSG00000112539.9 0.695 SPAG17/ENSG00000155761.9 0.693 TMEM67/ENSG00000164953.11 0.691 RSPH4A/ENSG00000111834.8 0.678 TTC18/ENSG00000156042.13 0.67 KIF9/ENSG00000088727.8 0.668 DNAH7/ENSG00000118997.9 0.665 SPAG16/ENSG00000144451.14 0.662 SPAG1/ENSG00000104450.8 0.661 EFCAB1/ENSG00000034239.6 0.661 POLR2I/ENSG00000105258.4 0.648 DPCD/ENSG00000166171.8 0.638 IK/ENSG00000113141.10 0.635 C9ORF135/ENSG00000204711.4 0.631 IFT57/ENSG00000114446.4 0.63 IQCK/ENSG00000174628.12 0.627 TCTEX1D2/ENSG00000213123.5 0.626 ADPRHL2/ENSG00000116863.10 0.62 DNALI1/ENSG00000163879.9 0.618 FAM154B/ENSG00000188659.5 0.617 DRC1/ENSG00000157856.6 0.606 RP11-620J15.3/ENSG00000257698.1 0.606 SPATA17/ENSG00000162814.6 0.578 NPHP1/ENSG00000144061.8 0.575 TTLL5/ENSG00000119685.14 0.566 MORN5/ENSG00000185681.8 0.566 CCDC30/ENSG00000186409.10 0.566 MAPK10/ENSG00000109339.14 0.561 EFCAB2/ENSG00000203666.8 0.558 WDR54/ENSG00000005448.12 0.554 AC130352.1/ENSG00000205873.2 0.545 LRRC49/ENSG00000137821.7 0.535 ZNF474/ENSG00000164185.4 0.532 TEKT2/ENSG00000092850.7 0.53 LRRIQ1/ENSG00000133640.13 0.529 SPEF2/ENSG00000152582.8 0.527 IFT52/ENSG00000101052.8 0.514 RSPH1/ENSG00000160188.5 0.511 CCDC19/ENSG00000213085.5 0.505 NME5/ENSG00000112981.3 0.503 IQCG/ENSG00000114473.9 0.501 DNAL1/ENSG00000119661.9 0.481 "APITD1,APITD1-CORT/ENSG00000175279.17" 0.481 CTC-340A15.2/ENSG00000241956.5 0.477 FAM76A/ENSG00000009780.11 0.472 BUD31/ENSG00000106245.5 0.471 ENKUR/ENSG00000151023.12 0.469 NUDC/ENSG00000090273.9 0.465 C10ORF10/ENSG00000165507.8 0.461 HYDIN/ENSG00000157423.13 0.46 C11ORF74/ENSG00000166352.11 0.457 ANXA4/ENSG00000196975.9 0.456 C21ORF59/ENSG00000159079.14 0.454 WRB/ENSG00000182093.9 0.452 UFC1/ENSG00000143222.7 0.452 CPE/ENSG00000109472.9 0.44 C11ORF49/ENSG00000149179.8 0.432 ZMYND10/ENSG00000004838.9 0.426 RP11-56G10.2/ENSG00000257386.1 0.425 PACRG/ENSG00000112530.7 0.423 B9D1/ENSG00000108641.10 0.421 MOB1B/ENSG00000173542.4 0.415 C1ORF158/ENSG00000157330.5 0.412 C20ORF85/ENSG00000124237.5 0.408 ULK4/ENSG00000168038.6 0.397 RPGR/ENSG00000156313.8 0.394 ANKRD54/ENSG00000100124.7 0.393 C9ORF116/ENSG00000160345.8 0.392 RIIAD1/ENSG00000178796.8 0.39 IGF2/ENSG00000167244.12 0.388 NME7/ENSG00000143156.9 0.387 SLC38A6/ENSG00000139974.11 0.382 RP11-18C24.6/ENSG00000248008.2 0.381 DYX1C1/ENSG00000256061.3 0.381 MAP3K19/ENSG00000176601.7 0.374 WDR63/ENSG00000162643.8 0.374 TTLL10/ENSG00000162571.9 0.37 TP53INP1/ENSG00000164938.9 0.367 PPIL6/ENSG00000185250.10 0.367 FANK1/ENSG00000203780.6 0.366 UBXN11/ENSG00000158062.16 0.365 TUBB4B/ENSG00000188229.5 0.365 LRRC6/ENSG00000129295.4 0.363 TTC26/ENSG00000105948.9 0.363 CDHR3/ENSG00000128536.11 0.361 SIM1/ENSG00000112246.5 0.36 EFCAB10/ENSG00000185055.6 0.357 ITGB3BP/ENSG00000142856.12 0.351 RP11-446H18.3/ENSG00000243701.1 0.349 MAK/ENSG00000111837.7 0.348 C14ORF142/ENSG00000170270.4 0.348 IFT43/ENSG00000119650.8 0.346 FLJ27352/ENSG00000261652.2 0.345 ARL4A/ENSG00000122644.8 0.344 BBS4/ENSG00000140463.9 0.344 IFT46/ENSG00000118096.3 0.34 EFHC2/ENSG00000183690.11 0.338 FAM227A/ENSG00000184949.10 0.337 ZBBX/ENSG00000169064.8 0.333 C12ORF55/ENSG00000188596.4 0.333 FAM81B/ENSG00000153347.5 0.329 MNS1/ENSG00000138587.5 0.329 MYO10/ENSG00000145555.10 0.328 VWA3A/ENSG00000175267.10 0.328 MAATS1/ENSG00000183833.12 0.328 TEX9/ENSG00000151575.10 0.327 WDR78/ENSG00000152763.12 0.326 TMEM232/ENSG00000186952.10 0.322 CIB1/ENSG00000185043.6 0.321 CCDC65/ENSG00000139537.6 0.319 C6ORF165/ENSG00000213204.3 0.319 CDADC1/ENSG00000102543.10 0.318 BCO2/ENSG00000197580.7 0.316 LINC00539/ENSG00000244054.1 0.315 CCDC57/ENSG00000176155.13 0.313 TEKT1/ENSG00000167858.8 0.311 TCTN1/ENSG00000204852.11 0.311 DIXDC1/ENSG00000150764.9 0.31 TMEM231/ENSG00000205084.5 0.308 TMX4/ENSG00000125827.4 0.307 DIO1/ENSG00000211452.6 0.305 FOS/ENSG00000170345.5 0.303 SYS1/ENSG00000204070.5 0.3 WDR52/ENSG00000206530.4 0.298 DZIP3/ENSG00000198919.8 0.295 RUVBL2/ENSG00000183207.8 0.29 PELI2/ENSG00000139946.5 0.288 STK33/ENSG00000130413.11 0.287 LRRC23/ENSG00000010626.10 0.287 DCDC1/ENSG00000170959.10 0.286 AL365202.1/ENSG00000203286.4 0.285 DNAH6/ENSG00000115423.14 0.284 SERPINB1/ENSG00000021355.8 0.283 JKAMP/ENSG00000050130.13 0.28 CCDC181/ENSG00000117477.8 0.279 GPATCH2/ENSG00000092978.6 0.278 LYRM5/ENSG00000205707.5 0.278 C7ORF57/ENSG00000164746.9 0.277 LRTOMT/ENSG00000184154.8 0.276 WDR96/ENSG00000197748.8 0.275 WDR60/ENSG00000126870.11 0.274 DYNC2H1/ENSG00000187240.9 0.271 RP11-98D18.15/ENSG00000269621.1 0.271 GALNS/ENSG00000141012.8 0.268 LRRC9/ENSG00000131951.6 0.268 ERCC4/ENSG00000175595.10 0.267 CDK10/ENSG00000185324.17 0.267 TTC21A/ENSG00000168026.12 0.266 ARL6/ENSG00000113966.5 0.266 RIMS2/ENSG00000176406.16 0.266 WDR16/ENSG00000166596.10 0.265 CRIP2/ENSG00000182809.6 0.265 DYNLRB2/ENSG00000168589.10 0.265 CEP41/ENSG00000106477.13 0.264 PIBF1/ENSG00000083535.11 0.263 STX2/ENSG00000111450.9 0.261 ARL3/ENSG00000138175.7 0.26 CCDC146/ENSG00000135205.10 0.259 AC005339.2/ENSG00000268565.1 0.257 LRRC37B/ENSG00000185158.8 0.257 TTLL9/ENSG00000131044.12 0.257 DUSP18/ENSG00000167065.9 0.256 RFX2/ENSG00000087903.8 0.255 PDLIM5/ENSG00000163110.10 0.254 CCDC41/ENSG00000173588.9 0.254 ALCAM/ENSG00000170017.8 0.253 PSMD10/ENSG00000101843.14 0.252 C7ORF63/ENSG00000105792.15 Overrepresented GO terms in EP #12: Term Pvalue cell part morphogenesis 5.25E-24 cell projection organization 8.23E-24 cell morphogenesis 1.52E-20 microtubule cytoskeleton organization 5.26E-15 cilium assembly 1.67E-13 anatomical structure formation involved in morphogenesis 1.96E-13 microtubule-based process 4.03E-11 spermatogenesis 5.61E-10 cellular developmental process 1.13E-09 cellular component assembly 1.71E-09 multi-organism reproductive process 3.31E-08 gamete generation 5.42E-08 smoothened signaling pathway 1.09E-07 determination of left/right symmetry 9.65E-07 single-organism organelle organization 1.12E-06 axoneme assembly 1.48E-06 inner dynein arm assembly 1.58E-06 specification of symmetry 2.04E-06 movement of cell or subcellular component 2.08E-06 reproduction 2.16E-06 intraciliary transport 9.02E-06 cilium movement 1.79E-05 anatomical structure development 2.02E-05 cellular component organization or biogenesis 2.38E-05 cilium morphogenesis 4.46E-05 spermatid development 4.46E-05 transport along microtubule 4.96E-05 protein localization to cilium 0.000255187 epithelial cilium movement 0.000568441 sperm axoneme assembly 0.001085216 intraciliary retrograde transport 0.001617971 ventricular system development 0.002096321 cilium-dependent cell motility 0.002139006 cellular process involved in reproduction in multicellular organism 0.002230937 axonemal central apparatus assembly 0.002450864 cilium movement involved in cell motility 0.003139824 motile cilium assembly 0.004161122 nonmotile primary cilium assembly 0.004852434 outer dynein arm assembly 0.008450919 protein localization to ciliary transition zone 0.014545857 protein localization to centrosome 0.014883191 axonemal dynein complex assembly 0.022263801 left/right pattern formation 0.023822072 flagellated sperm motility 0.029870847 cellular macromolecular complex assembly 0.037043204 cellular process 0.049320111 --------------------------------------------- "EP #13: 697 cells, 413 genes" "Fraction of cells from each time pt- hesc_: 0.943396226415094, stage1_: 0.968253968253968, stage2_: 0.897058823529412, stage3_: 0.742857142857143, St4_3_: 0.931034482758621, stage4: 0.714285714285714, St5_3_: 0.958904109589041, stage5_: 0.984375, stage6.2_: 1, stage6.7_: 1, stage6.14_: 0.761194029850746, " Top Genes: 1.506 P4HB/ENSG00000185624.9 1.426 FTH1/ENSG00000167996.11 1.422 MIF/ENSG00000240972.1 1.347 CALM1/ENSG00000198668.6 1.287 NDUFB7/ENSG00000099795.2 1.187 PFN1/ENSG00000108518.7 1.185 RABAC1/ENSG00000105404.6 1.175 EIF5A/ENSG00000132507.13 1.109 COX5A/ENSG00000178741.7 1.099 TMEM147/ENSG00000105677.7 1.094 GPX4/ENSG00000167468.12 1.064 AP000350.4/ENSG00000218537.1 1.05 RPS2/ENSG00000140988.11 1.039 HM13/ENSG00000101294.12 1.029 NDUFAB1/ENSG00000004779.5 0.971 MDK/ENSG00000110492.11 0.948 TIMM13/ENSG00000099800.3 0.941 TBCB/ENSG00000105254.6 0.914 AURKAIP1/ENSG00000175756.9 0.91 EIF5/ENSG00000100664.6 0.89 GUK1/ENSG00000143774.12 0.888 POLR2E/ENSG00000099817.7 0.884 EIF3F/ENSG00000175390.8 0.88 ARF5/ENSG00000004059.6 0.856 GPX1/ENSG00000233276.2 0.855 APRT/ENSG00000198931.6 0.853 SPINT2/ENSG00000167642.8 0.838 LSM4/ENSG00000130520.4 0.838 UQCRC1/ENSG00000010256.6 0.835 KRT8/ENSG00000170421.7 0.812 C11ORF31/ENSG00000211450.5 0.806 SPAG7/ENSG00000091640.3 0.806 FKBP1A/ENSG00000088832.10 0.8 NDUFB10/ENSG00000140990.10 0.797 PDCD6/ENSG00000249915.3 0.791 TMED4/ENSG00000158604.10 0.782 KRT19/ENSG00000171345.9 0.778 ARL2/ENSG00000213465.3 0.767 CTTN/ENSG00000085733.11 0.765 SNRPB/ENSG00000125835.13 0.765 OAZ1/ENSG00000104904.7 0.759 EIF4EBP1/ENSG00000187840.4 0.754 FKBP2/ENSG00000173486.8 0.753 UBXN1/ENSG00000162191.9 0.748 RPL13/ENSG00000167526.9 0.747 CFL1/ENSG00000172757.7 0.739 CUEDC2/ENSG00000107874.6 0.729 PSMA7/ENSG00000101182.10 0.727 LSM7/ENSG00000130332.9 0.713 ARL6IP4/ENSG00000182196.8 0.698 TUFM/ENSG00000178952.4 0.693 CCT7/ENSG00000135624.11 0.69 MRPL28/ENSG00000086504.11 0.69 ARF1/ENSG00000143761.9 0.684 YWHAQ/ENSG00000134308.9 0.679 MRPS24/ENSG00000062582.9 0.678 APOA1BP/ENSG00000163382.7 0.677 NUDC/ENSG00000090273.9 0.674 NDUFS8/ENSG00000110717.6 0.669 LYPLA2/ENSG00000011009.6 0.668 EBP/ENSG00000147155.6 0.668 SLC25A3/ENSG00000075415.8 0.664 ARL16/ENSG00000214087.4 0.658 CNPY2/ENSG00000257727.1 0.647 VCP/ENSG00000165280.11 0.635 DCXR/ENSG00000169738.2 0.624 EIF4G1/ENSG00000114867.14 0.623 PLEKHJ1/ENSG00000104886.4 0.62 GNG5/ENSG00000174021.6 0.62 AC107016.1/ENSG00000225410.1 0.618 SEC13/ENSG00000157020.13 0.617 PDIA3/ENSG00000167004.8 0.616 NDUFB11/ENSG00000147123.10 0.616 ATXN10/ENSG00000130638.11 0.613 DCTN2/ENSG00000175203.11 0.606 PUF60/ENSG00000179950.9 0.604 PPP4C/ENSG00000149923.9 0.602 MTG1/ENSG00000148824.13 0.601 TIMM17B/ENSG00000126768.7 0.601 NAA10/ENSG00000102030.11 0.597 RPS19BP1/ENSG00000187051.4 0.588 AC009005.3/ENSG00000267276.1 0.587 MRPL55/ENSG00000162910.14 0.586 ISCU/ENSG00000136003.11 0.585 TUBB3/ENSG00000258947.2 0.583 NDUFS3/ENSG00000213619.5 0.582 PSMD2/ENSG00000175166.12 0.581 CTSB/ENSG00000164733.16 0.58 PTPMT1/ENSG00000110536.9 0.579 MRPL52/ENSG00000172590.14 0.575 JTB/ENSG00000143543.10 0.572 SLC3A2/ENSG00000168003.12 0.572 AC011933.1/ENSG00000257073.1 0.572 EIF4A1/ENSG00000161960.10 0.572 TMEM66/ENSG00000133872.9 0.566 HINT2/ENSG00000137133.6 0.566 MRPL9/ENSG00000143436.6 0.563 IMP4/ENSG00000136718.5 0.558 QPRT/ENSG00000103485.12 0.557 C21ORF33/ENSG00000160221.12 0.556 MLF2/ENSG00000089693.6 0.555 PAFAH1B3/ENSG00000079462.3 0.554 AP2S1/ENSG00000042753.7 0.554 CNP/ENSG00000173786.11 0.553 PYURF/ENSG00000145337.4 0.552 TSC22D1/ENSG00000102804.10 0.55 PPP2R1A/ENSG00000105568.13 0.547 SLC25A39/ENSG00000013306.11 0.546 COPE/ENSG00000105669.8 0.544 LMAN2/ENSG00000169223.10 0.539 EMC6/ENSG00000127774.6 0.537 MRFAP1/ENSG00000179010.10 0.536 LRPAP1/ENSG00000163956.6 0.536 SNF8/ENSG00000159210.4 0.532 MFF/ENSG00000168958.15 0.531 FAM96B/ENSG00000166595.7 0.529 TRAPPC6A/ENSG00000007255.6 0.528 KRT18/ENSG00000111057.6 0.525 ZDHHC12/ENSG00000160446.14 0.524 ITPA/ENSG00000125877.7 0.519 PPP1CA/ENSG00000172531.10 0.519 BID/ENSG00000015475.14 0.518 CHCHD2/ENSG00000106153.12 0.516 EIF3G/ENSG00000130811.6 0.514 NHP2/ENSG00000145912.4 0.508 IDH3B/ENSG00000101365.16 0.508 TECR/ENSG00000099797.7 0.507 PSMD8/ENSG00000099341.7 0.507 CLPP/ENSG00000125656.4 0.504 CD320/ENSG00000167775.6 0.504 RHEB/ENSG00000106615.5 0.5 TMED2/ENSG00000086598.6 0.498 ZNF706/ENSG00000120963.7 0.497 FAM32A/ENSG00000105058.7 0.496 PRDX5/ENSG00000126432.9 0.496 PKIG/ENSG00000168734.9 0.495 COLGALT1/ENSG00000130309.6 0.494 PTTG1IP/ENSG00000183255.7 0.492 NOSIP/ENSG00000142546.9 0.488 PGAM1/ENSG00000171314.8 0.488 FAM127B/ENSG00000203950.6 0.488 SRA1/ENSG00000213523.5 0.487 UXT/ENSG00000126756.7 0.485 SSNA1/ENSG00000176101.7 0.485 CPSF1/ENSG00000071894.10 0.483 RNPS1/ENSG00000205937.7 0.483 BRD3/ENSG00000169925.12 0.481 CALR/ENSG00000179218.8 0.474 SIVA1/ENSG00000184990.8 0.474 MRPL34/ENSG00000130312.2 0.474 SNX17/ENSG00000115234.6 0.473 PRDX4/ENSG00000123131.8 0.471 ZNF32/ENSG00000169740.9 0.471 RPUSD3/ENSG00000156990.10 0.468 SLC25A1/ENSG00000100075.5 0.466 PTOV1/ENSG00000104960.11 0.465 CDK4/ENSG00000135446.12 0.464 PHB2/ENSG00000215021.3 0.461 GCHFR/ENSG00000137880.4 0.46 MRPL38/ENSG00000204316.8 0.459 NDUFV1/ENSG00000167792.7 0.459 SDR39U1/ENSG00000100445.12 0.458 CCDC124/ENSG00000007080.6 0.458 ATP1B3/ENSG00000069849.6 0.458 TRIM28/ENSG00000130726.7 0.456 PPA1/ENSG00000180817.6 0.455 CCNL2/ENSG00000221978.7 0.455 EEF1D/ENSG00000104529.13 0.455 UQCRFS1/ENSG00000169021.4 0.454 NDUFS7/ENSG00000115286.14 0.453 CYC1/ENSG00000179091.4 0.449 NGRN/ENSG00000182768.7 0.446 RAP1B/ENSG00000127314.13 0.445 NME4/ENSG00000103202.8 0.442 MRPS34/ENSG00000074071.9 0.441 DGCR6L/ENSG00000128185.5 0.441 RPN2/ENSG00000118705.12 0.439 EHMT1/ENSG00000181090.13 0.435 TXLNA/ENSG00000084652.11 0.433 POLR2L/ENSG00000177700.5 0.433 PMPCA/ENSG00000165688.7 0.432 RANBP1/ENSG00000099901.12 0.43 DHRS3/ENSG00000162496.4 0.428 FAM195B/ENSG00000225663.3 0.425 LINC00665/ENSG00000232677.2 0.422 SMARCA4/ENSG00000127616.12 0.421 PARP1/ENSG00000143799.8 0.421 ALKBH7/ENSG00000125652.3 0.42 MZT2B/ENSG00000152082.9 0.419 IMP3/ENSG00000177971.7 0.418 SURF2/ENSG00000148291.5 0.417 NDUFS6/ENSG00000145494.7 0.417 TFG/ENSG00000114354.8 0.416 AL645728.2/ENSG00000215791.2 0.416 PHB/ENSG00000167085.6 0.413 RP11-138C9.1/ENSG00000264558.1 0.411 HERPUD1/ENSG00000051108.10 0.41 CREB3/ENSG00000107175.6 0.409 DDX41/ENSG00000183258.7 0.407 BSG/ENSG00000172270.14 0.406 UBE2B/ENSG00000119048.3 0.405 RHBDD2/ENSG00000005486.12 0.405 UBE2F/ENSG00000184182.14 0.403 PDIA4/ENSG00000155660.6 0.403 TSPAN3/ENSG00000140391.10 0.401 C16ORF13/ENSG00000130731.11 0.401 EXOSC4/ENSG00000178896.6 0.4 FUCA2/ENSG00000001036.8 0.398 PCBP1/ENSG00000169564.5 0.398 PEPD/ENSG00000124299.8 0.397 ALG3/ENSG00000214160.5 0.396 FLII/ENSG00000177731.11 0.392 PDIA6/ENSG00000143870.8 0.391 MRPL37/ENSG00000116221.11 0.389 DNPH1/ENSG00000112667.8 0.386 QDPR/ENSG00000151552.7 0.384 GPS2/ENSG00000132522.11 0.384 RP11-252A24.7/ENSG00000260539.1 0.384 YIF1A/ENSG00000174851.10 0.383 C19ORF10/ENSG00000074842.3 0.383 GRN/ENSG00000030582.12 0.382 MLST8/ENSG00000167965.13 0.38 PSMG3/ENSG00000157778.4 0.379 SNRNP40/ENSG00000060688.8 0.379 EPB41L4A-AS1/ENSG00000224032.2 0.378 AP1G2/ENSG00000213983.7 0.375 C6ORF48/ENSG00000204387.8 0.374 YIF1B/ENSG00000167645.12 0.373 GCSH/ENSG00000140905.5 0.37 MPLKIP/ENSG00000168303.5 0.37 SLC25A4/ENSG00000151729.5 0.368 COX5B/ENSG00000135940.2 0.367 UBL7/ENSG00000138629.11 0.365 STK25/ENSG00000115694.10 0.364 PRPF31/ENSG00000105618.9 0.364 NOL12/ENSG00000256872.1 0.364 AP3S1/ENSG00000177879.10 0.363 GNAI2/ENSG00000114353.12 0.363 CAPN1/ENSG00000014216.11 0.362 PIN1/ENSG00000127445.9 0.361 NARF/ENSG00000141562.12 0.36 CALM3/ENSG00000160014.12 0.357 SFXN1/ENSG00000164466.8 0.357 COQ4/ENSG00000167113.5 0.356 SLC25A37/ENSG00000147454.9 0.356 YWHAB/ENSG00000166913.8 0.355 UROS/ENSG00000188690.8 0.355 NCOR1/ENSG00000141027.16 0.354 ZFYVE21/ENSG00000100711.9 0.354 RAD23A/ENSG00000179262.4 0.352 GADD45GIP1/ENSG00000179271.1 0.352 CDK2AP2/ENSG00000167797.3 0.352 PLD3/ENSG00000105223.14 0.352 FAU/ENSG00000149806.6 0.351 CCDC12/ENSG00000160799.7 0.35 IDH2/ENSG00000182054.5 0.35 SURF4/ENSG00000148248.9 0.349 PSMD9/ENSG00000110801.8 0.349 ISCA2/ENSG00000165898.9 0.349 CD81/ENSG00000110651.7 0.345 TSEN15/ENSG00000198860.7 0.344 C21ORF59/ENSG00000159079.14 0.343 TRAPPC5/ENSG00000181029.7 0.342 SYNGR2/ENSG00000108639.3 0.34 DUS1L/ENSG00000169718.13 0.34 AP2M1/ENSG00000161203.9 0.34 CDK10/ENSG00000185324.17 0.338 NINJ1/ENSG00000131669.5 0.337 CHCHD5/ENSG00000125611.11 0.337 MRPL53/ENSG00000204822.6 0.337 CCDC167/ENSG00000198937.8 0.336 DDT/ENSG00000099977.9 0.336 TCF25/ENSG00000141002.13 0.335 CDC37/ENSG00000105401.2 0.335 SLC25A11/ENSG00000108528.9 0.335 ADRM1/ENSG00000130706.8 0.334 PPCS/ENSG00000127125.7 0.333 PARL/ENSG00000175193.8 0.333 APLP2/ENSG00000084234.12 0.332 INTS10/ENSG00000104613.6 0.332 C9ORF16/ENSG00000171159.4 0.331 MRPS26/ENSG00000125901.5 0.331 TBC1D1/ENSG00000065882.11 0.331 DDX56/ENSG00000136271.6 0.33 DIABLO/ENSG00000184047.11 0.33 MALSU1/ENSG00000156928.4 0.329 C1QBP/ENSG00000108561.4 0.329 STXBP2/ENSG00000076944.10 0.328 PPP2CA/ENSG00000113575.5 0.326 HOOK2/ENSG00000095066.7 0.326 DTD1/ENSG00000125821.7 0.326 TMEM9/ENSG00000116857.11 0.326 POP7/ENSG00000172336.4 0.324 MRPL46/ENSG00000259494.1 0.323 NFYC/ENSG00000066136.15 0.322 KLHL12/ENSG00000117153.11 0.321 DNAH14/ENSG00000185842.10 0.318 DMKN/ENSG00000161249.16 0.318 TBCC/ENSG00000124659.5 0.317 TOR1A/ENSG00000136827.11 0.316 MRPS2/ENSG00000122140.6 0.314 FLOT1/ENSG00000137312.10 0.314 ATP6AP2/ENSG00000182220.9 0.313 NUTM2A-AS1/ENSG00000223482.3 0.312 RQCD1/ENSG00000144580.9 0.311 MAP1LC3B/ENSG00000140941.8 0.31 ETFA/ENSG00000140374.11 0.31 POR/ENSG00000127948.9 0.308 POLR2D/ENSG00000144231.6 0.305 SRP68/ENSG00000167881.10 0.304 MZT2A/ENSG00000173272.9 0.304 RER1/ENSG00000157916.13 0.302 CTC-425F1.4/ENSG00000267458.1 0.302 SUZ12P/ENSG00000264538.2 0.302 USP22/ENSG00000124422.7 0.301 COMMD5/ENSG00000170619.8 0.301 GGH/ENSG00000137563.7 0.301 TMED3/ENSG00000166557.8 0.3 RUVBL2/ENSG00000183207.8 0.3 "PMF1,PMF1-BGLAP/ENSG00000160783.13" 0.3 NELFE/ENSG00000204356.7 0.297 VIMP/ENSG00000131871.10 0.296 NUBP2/ENSG00000095906.12 0.295 TKT/ENSG00000163931.11 0.295 HSPA5/ENSG00000044574.7 0.295 BABAM1/ENSG00000105393.11 0.294 EAF1/ENSG00000144597.9 0.294 GUCD1/ENSG00000138867.12 0.294 ITGB1BP1/ENSG00000119185.8 0.294 LSM10/ENSG00000181817.5 0.293 CCDC47/ENSG00000108588.8 0.293 RP11-667K14.4/ENSG00000262533.1 0.292 BAD/ENSG00000002330.9 0.291 SCAND1/ENSG00000171222.6 0.29 TMEM223/ENSG00000168569.7 0.29 C17ORF62/ENSG00000178927.11 0.29 MTCH1/ENSG00000137409.14 0.289 TMEM134/ENSG00000172663.4 0.289 COQ6/ENSG00000119723.11 0.288 ELOF1/ENSG00000130165.6 0.288 ICT1/ENSG00000167862.5 0.288 RNH1/ENSG00000023191.12 0.288 GPAA1/ENSG00000197858.6 0.287 PSMG1/ENSG00000183527.7 0.287 LRRC16A/ENSG00000079691.15 0.286 MTHFS/ENSG00000136371.5 0.286 WIBG/ENSG00000170473.12 0.285 ISOC1/ENSG00000066583.7 0.284 FKBP1B/ENSG00000119782.9 0.283 RAP1GDS1/ENSG00000138698.9 0.283 NUDT16L1/ENSG00000168101.10 0.283 LSMD1/ENSG00000183011.9 0.282 CSTB/ENSG00000160213.5 0.281 CNPY3/ENSG00000137161.12 0.281 NRD1/ENSG00000078618.15 0.28 MEA1/ENSG00000124733.3 0.279 WDR18/ENSG00000065268.5 0.279 TBC1D7/ENSG00000145979.12 0.279 MRPL3/ENSG00000114686.4 0.278 BRMS1/ENSG00000174744.9 0.278 ECHS1/ENSG00000127884.4 0.278 ASCC2/ENSG00000100325.10 0.278 TIMM44/ENSG00000104980.3 0.277 CBR1/ENSG00000159228.8 0.276 ISYNA1/ENSG00000105655.12 0.275 MRPS30/ENSG00000112996.5 0.275 TM7SF2/ENSG00000149809.10 0.274 ACBD6/ENSG00000135847.5 0.273 GTF3A/ENSG00000122034.8 0.273 C7ORF50/ENSG00000146540.10 0.273 HIST1H1E/ENSG00000168298.4 0.272 DCUN1D5/ENSG00000137692.7 0.272 SNX3/ENSG00000112335.10 0.272 ABHD11/ENSG00000106077.14 0.271 LUC7L/ENSG00000007392.12 0.27 MRPL54/ENSG00000183617.4 0.27 SUMO3/ENSG00000184900.11 0.269 LLGL2/ENSG00000073350.9 0.267 CDK5/ENSG00000164885.8 0.267 MTFP1/ENSG00000242114.1 0.267 IFT27/ENSG00000100360.10 0.266 NRBP1/ENSG00000115216.9 0.266 EHMT2/ENSG00000204371.7 0.266 CRYM/ENSG00000103316.6 0.266 CARD10/ENSG00000100065.10 0.264 NAPA/ENSG00000105402.3 0.264 ANKRD40/ENSG00000154945.6 0.263 CLTA/ENSG00000122705.12 0.263 C1ORF43/ENSG00000143612.14 0.262 AAMP/ENSG00000127837.5 0.261 CENPT/ENSG00000102901.8 0.261 COPS7A/ENSG00000111652.5 0.26 WASF2/ENSG00000158195.6 0.259 MRPS15/ENSG00000116898.7 0.258 WDR13/ENSG00000101940.11 0.257 WDR46/ENSG00000227057.3 0.256 MECR/ENSG00000116353.11 0.256 EIF2B1/ENSG00000111361.7 0.254 ARPC1B/ENSG00000130429.8 0.254 NTHL1/ENSG00000065057.2 0.254 NOC2L/ENSG00000188976.6 0.253 ARL8B/ENSG00000134108.8 0.253 SQSTM1/ENSG00000161011.15 0.252 AK1/ENSG00000106992.13 0.252 TRPT1/ENSG00000149743.9 0.252 TEN1/ENSG00000257949.2 0.252 DICER1-AS1/ENSG00000235706.3 0.252 CLPTM1L/ENSG00000049656.9 0.251 TM9SF1/ENSG00000100926.10 0.251 C2ORF68/ENSG00000168887.6 0.251 ZMAT5/ENSG00000100319.11 0.251 AC006011.4/ENSG00000244563.1 0.25 TRMT61B/ENSG00000171103.6 Overrepresented GO terms in EP #13: Term Pvalue mitochondrion organization 9.15E-17 translation 2.60E-13 mitochondrial translational elongation 2.66E-13 mitochondrial translational termination 5.59E-12 amide biosynthetic process 6.43E-11 peptide metabolic process 1.27E-10 cellular protein complex disassembly 1.28E-08 macromolecular complex disassembly 2.81E-08 protein complex subunit organization 4.85E-08 organonitrogen compound biosynthetic process 6.66E-08 oxidative phosphorylation 7.01E-08 purine ribonucleoside triphosphate metabolic process 3.58E-07 energy derivation by oxidation of organic compounds 4.20E-07 small molecule metabolic process 1.09E-06 nucleoside triphosphate metabolic process 2.91E-06 nucleotide metabolic process 4.84E-06 purine ribonucleoside monophosphate metabolic process 5.58E-06 nucleoside monophosphate metabolic process 6.98E-06 establishment of localization in cell 1.59E-05 purine ribonucleoside metabolic process 2.28E-05 "mitochondrial electron transport, NADH to ubiquinone " 5.78E-05 purine ribonucleotide metabolic process 0.000103282 nucleoside metabolic process 0.000104718 ribose phosphate metabolic process 0.00012129 ER to Golgi vesicle-mediated transport 0.000163836 purine-containing compound metabolic process 0.000195895 posttranscriptional regulation of gene expression 0.000239795 mitochondrial respiratory chain complex I assembly 0.000273658 intracellular protein transport 0.00034382 regulation of protein metabolic process 0.000375784 interspecies interaction between organisms 0.000685232 "regulation of symbiosis, encompassing mutualism through parasitism " 0.00112074 protein maturation by protein folding 0.00154255 cellular component assembly 0.001827761 macromolecule catabolic process 0.002211877 negative regulation of ryanodine-sensitive calcium-release channel activity 0.002520539 substantia nigra development 0.002538247 protein complex assembly 0.002573757 regulation of cellular amide metabolic process 0.003077478 cofactor metabolic process 0.003339535 establishment of protein localization 0.003821815 multi-organism cellular process 0.00385274 cellular macromolecule localization 0.004074342 positive regulation of cyclic-nucleotide phosphodiesterase activity 0.005282161 primary metabolic process 0.005461295 cellular nitrogen compound metabolic process 0.005601921 protein folding in endoplasmic reticulum 0.005710987 regulation of translational initiation 0.005782612 cellular macromolecular complex assembly 0.007002288 cellular component organization 0.007489755 membrane budding 0.008012805 positive regulation of sequestering of calcium ion 0.008087951 RNA splicing 0.008128625 single-organism catabolic process 0.008461663 response to endoplasmic reticulum stress 0.009242416 regulation of mitochondrion organization 0.010955846 cellular catabolic process 0.011066724 proteasome assembly 0.011101972 negative regulation of intrinsic apoptotic signaling pathway 0.013032408 negative regulation of calcium ion transport into cytosol 0.014843604 positive regulation of cellular protein metabolic process 0.015748379 cell redox homeostasis 0.015964179 nucleobase-containing compound catabolic process 0.018415107 regulation of apoptotic signaling pathway 0.01908879 positive regulation of viral transcription 0.02005715 negative regulation of protein phosphatase type 2B activity 0.022178314 COPII vesicle coating 0.022354929 mRNA catabolic process 0.024631691 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.024882064 iron-sulfur cluster assembly 0.024882064 negative regulation of cell communication 0.024895237 "retrograde vesicle-mediated transport, Golgi to ER " 0.025009639 apoptotic process 0.026116417 negative regulation of signaling 0.026341176 mitochondrial transport 0.026987049 regulation of protein dephosphorylation 0.027236636 positive regulation of ryanodine-sensitive calcium-release channel activity 0.027974979 negative regulation of intracellular steroid hormone receptor signaling pathway 0.028370888 mitochondrial ATP synthesis coupled electron transport 0.030079997 ribonucleoprotein complex biogenesis 0.030638777 organonitrogen compound metabolic process 0.031514639 respiratory electron transport chain 0.033078487 antigen processing and presentation of peptide antigen 0.03654337 "vesicle targeting, to, from or within Golgi " 0.036614676 chaperone-mediated protein folding 0.036991777 positive regulation of viral process 0.037983922 regulation of cell communication by electrical coupling involved in cardiac conduction 0.041191193 "nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay " 0.04810483 --------------------------------------------- "EP #14: 181 cells, 246 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0.0147058823529412, stage3_: 0.985714285714286, St4_3_: 0.781609195402299, stage4: 0.414285714285714, St5_3_: 0.123287671232877, stage5_: 0.046875, stage6.2_: 0.024390243902439, stage6.7_: 0, stage6.14_: 0, " Top Genes: 2.39 AL590714.1/ENSG00000268387.1 2.301 RP11-834C11.4/ENSG00000250742.1 2.272 AC132217.4/ENSG00000240801.1 2.22 APOA2/ENSG00000158874.6 2.119 TTR/ENSG00000118271.5 2.087 AMBP/ENSG00000106927.7 1.926 HOXA1/ENSG00000105991.7 1.85 ANGPT2/ENSG00000091879.9 1.731 DHRS3/ENSG00000162496.4 1.716 FLRT2/ENSG00000185070.6 1.652 SKAP2/ENSG00000005020.8 1.648 PRSS1/ENSG00000204983.8 1.561 SERPINA1/ENSG00000197249.8 1.557 SHISA2/ENSG00000180730.4 1.466 IGF2/ENSG00000167244.12 1.419 MEIS1/ENSG00000143995.14 1.369 SERPINB6/ENSG00000124570.13 1.288 NR6A1/ENSG00000148200.12 1.243 HOTAIRM1/ENSG00000233429.5 1.223 CPB1/ENSG00000153002.7 1.197 CALB1/ENSG00000104327.3 1.174 LINC00261/ENSG00000259974.1 1.125 DUSP6/ENSG00000139318.7 1.125 PLK2/ENSG00000145632.10 1.096 DPP6/ENSG00000130226.12 1.074 RP11-325F22.5/ENSG00000225329.1 1.063 GATA4/ENSG00000136574.13 1.063 CALD1/ENSG00000122786.15 1.044 PDHA1/ENSG00000131828.9 1.035 RABGAP1L/ENSG00000152061.17 1.008 GIF/ENSG00000134812.3 1.006 S100A11/ENSG00000163191.5 1.003 MTTP/ENSG00000138823.8 0.999 SEBOX/ENSG00000109072.7 0.987 FLRT3/ENSG00000125848.9 0.981 CTSB/ENSG00000164733.16 0.954 PRKAR1A/ENSG00000108946.8 0.914 APOA1/ENSG00000118137.5 0.898 CADM1/ENSG00000182985.11 0.893 MGST1/ENSG00000008394.7 0.875 LMO3/ENSG00000048540.10 0.843 ONECUT2/ENSG00000119547.4 0.835 VAMP8/ENSG00000118640.6 0.833 SERPINF1/ENSG00000132386.6 0.819 TFF3/ENSG00000160180.14 0.816 FN1/ENSG00000115414.14 0.808 PDGFA/ENSG00000197461.9 0.802 CAMK2D/ENSG00000145349.12 0.797 RBP1/ENSG00000114115.5 0.79 DLK1/ENSG00000185559.9 0.761 SPATS2L/ENSG00000196141.7 0.744 LYPD6B/ENSG00000150556.12 0.73 CYP26A1/ENSG00000095596.7 0.729 LRRC42/ENSG00000116212.10 0.718 SLITRK2/ENSG00000185985.7 0.715 PRSS3P2/ENSG00000250606.4 0.702 C5/ENSG00000106804.6 0.693 TMEM144/ENSG00000164124.6 0.681 CXXC4/ENSG00000168772.9 0.672 BAALC/ENSG00000164929.12 0.653 CCNG1/ENSG00000113328.14 0.624 GSTA2/ENSG00000244067.1 0.619 ELMO1/ENSG00000155849.11 0.608 FAM184A/ENSG00000111879.14 0.607 CGA/ENSG00000135346.4 0.605 GLYATL1P2/ENSG00000254717.2 0.596 TRIM5/ENSG00000132256.14 0.592 AMHR2/ENSG00000135409.6 0.59 FAM162A/ENSG00000114023.11 0.589 CDC42EP3/ENSG00000163171.6 0.582 GPC3/ENSG00000147257.9 0.581 NUAK1/ENSG00000074590.9 0.58 ALCAM/ENSG00000170017.8 0.573 WDR77/ENSG00000116455.9 0.572 DMD/ENSG00000198947.9 0.572 PRDM1/ENSG00000057657.10 0.566 DECR1/ENSG00000104325.2 0.565 RBFOX2/ENSG00000100320.18 0.563 EFHC1/ENSG00000096093.9 0.562 PDGFRA/ENSG00000134853.7 0.557 ARMC3/ENSG00000165309.9 0.554 AGO1/ENSG00000092847.6 0.548 SERPING1/ENSG00000149131.11 0.543 SORBS2/ENSG00000154556.13 0.531 VPS13D/ENSG00000048707.9 0.526 MEIS2/ENSG00000134138.14 0.523 IQGAP2/ENSG00000145703.11 0.518 CGN/ENSG00000143375.9 0.516 LAPTM4B/ENSG00000104341.12 0.512 TAF1A/ENSG00000143498.13 0.504 SOX11/ENSG00000176887.5 0.502 DCX/ENSG00000077279.12 0.497 RARB/ENSG00000077092.14 0.496 RIN2/ENSG00000132669.8 0.495 GNAI1/ENSG00000127955.11 0.491 NUMB/ENSG00000133961.15 0.483 ECH1/ENSG00000104823.4 0.482 RFX6/ENSG00000185002.5 0.481 VIL1/ENSG00000127831.6 0.479 PRTG/ENSG00000166450.7 0.478 SH3YL1/ENSG00000035115.17 0.478 ELMO2/ENSG00000062598.13 0.475 LPPR1/ENSG00000148123.10 0.47 CTC-273B12.8/ENSG00000269751.1 0.468 GSTA4/ENSG00000170899.6 0.465 ARL15/ENSG00000185305.6 0.463 COL4A6/ENSG00000197565.11 0.459 IVNS1ABP/ENSG00000116679.11 0.454 SMIM6/ENSG00000259120.2 0.452 CRYM/ENSG00000103316.6 0.451 PLIN2/ENSG00000147872.5 0.451 CDH18/ENSG00000145526.7 0.45 JKAMP/ENSG00000050130.13 0.447 ITSN1/ENSG00000205726.9 0.447 VSIG10/ENSG00000176834.9 0.446 AASS/ENSG00000008311.10 0.441 BMPR1B/ENSG00000138696.6 0.439 PDE11A/ENSG00000128655.11 0.439 AHI1/ENSG00000135541.16 0.436 PLEKHH2/ENSG00000152527.9 0.431 GALM/ENSG00000143891.12 0.428 TBPL1/ENSG00000028839.4 0.424 CCKBR/ENSG00000110148.5 0.424 RAB3B/ENSG00000169213.6 0.423 YAF2/ENSG00000015153.10 0.42 GNPDA1/ENSG00000113552.11 0.414 GSTA1/ENSG00000243955.1 0.411 SNCAIP/ENSG00000064692.14 0.409 LINC00305/ENSG00000179676.6 0.407 CACNB2/ENSG00000165995.14 0.405 RP11-318M2.3/ENSG00000253851.1 0.404 CLCN3/ENSG00000109572.9 0.403 PRCP/ENSG00000137509.5 0.403 TNFAIP8/ENSG00000145779.6 0.399 FRMD4B/ENSG00000114541.10 0.399 CBLL1/ENSG00000105879.6 0.399 BEX2/ENSG00000133134.7 0.399 IGDCC4/ENSG00000103742.7 0.399 RAD51C/ENSG00000108384.10 0.397 GCNT1/ENSG00000187210.8 0.397 PFKM/ENSG00000152556.11 0.395 F2/ENSG00000180210.10 0.395 IFT122/ENSG00000163913.7 0.395 LYST/ENSG00000143669.9 0.393 RP11-139K1.2/ENSG00000227560.1 0.392 ADAM28/ENSG00000042980.8 0.392 IFI16/ENSG00000163565.14 0.392 ABCA1/ENSG00000165029.11 0.388 NPY1R/ENSG00000164128.2 0.386 RP11-11N9.4/ENSG00000247134.2 0.385 BTG1/ENSG00000133639.3 0.385 ONECUT1/ENSG00000169856.6 0.383 SMIM20/ENSG00000250317.4 0.382 FRG1/ENSG00000109536.7 0.381 SERPINB9/ENSG00000170542.5 0.379 FAM126A/ENSG00000122591.7 0.375 TAGLN2/ENSG00000158710.10 0.372 GULP1/ENSG00000144366.11 0.371 LINC00607/ENSG00000235770.1 0.37 SPAG17/ENSG00000155761.9 0.367 KIF13B/ENSG00000197892.8 0.365 SCN7A/ENSG00000136546.9 0.362 CA14/ENSG00000118298.5 0.357 GPM6A/ENSG00000150625.12 0.355 POLR2G/ENSG00000168002.7 0.355 NEK11/ENSG00000114670.9 0.354 CASP6/ENSG00000138794.5 0.35 ACSL1/ENSG00000151726.9 0.348 PRSS3P1/ENSG00000250591.2 0.348 CTSL2/ENSG00000136943.6 0.344 NNAT/ENSG00000053438.7 0.343 KLF3/ENSG00000109787.8 0.34 RP11-771K4.1/ENSG00000256232.1 0.338 CTB-12O2.1/ENSG00000254226.1 0.336 ZFP36L2/ENSG00000152518.5 0.335 PRICKLE1/ENSG00000139174.6 0.335 RNF157/ENSG00000141576.10 0.335 FAM122C/ENSG00000156500.10 0.334 GFRA1/ENSG00000151892.10 0.333 MRPS31/ENSG00000102738.6 0.333 GSTK1/ENSG00000197448.9 0.331 ARHGAP26/ENSG00000145819.11 0.329 PRKAB2/ENSG00000131791.6 0.328 CAP2/ENSG00000112186.7 0.327 RP11-834C11.6/ENSG00000249388.1 0.326 CDHR3/ENSG00000128536.11 0.325 CCDC93/ENSG00000125633.6 0.325 PIFO/ENSG00000173947.9 0.32 DKK3/ENSG00000050165.13 0.32 CAPN6/ENSG00000077274.7 0.319 DDC/ENSG00000132437.13 0.318 CALCOCO2/ENSG00000136436.9 0.312 SLC25A27/ENSG00000153291.11 0.311 DYNC2LI1/ENSG00000138036.14 0.311 NUDT19/ENSG00000213965.3 0.307 WLS/ENSG00000116729.9 0.307 FAT3/ENSG00000165323.11 0.305 KCTD14/ENSG00000151364.11 0.305 PTN/ENSG00000105894.7 0.304 SCMH1/ENSG00000010803.12 0.301 TMEM206/ENSG00000065600.8 0.301 HNF1A-AS1/ENSG00000241388.2 0.3 NUP62CL/ENSG00000198088.6 0.299 APOM/ENSG00000204444.6 0.299 ELAVL4/ENSG00000162374.12 0.297 DDAH2/ENSG00000213722.4 0.295 ADD3/ENSG00000148700.9 0.295 RP11-168A11.4/ENSG00000251050.1 0.294 ERRFI1/ENSG00000116285.8 0.293 HABP2/ENSG00000148702.10 0.293 UCHL1/ENSG00000154277.8 0.293 TMEM56/ENSG00000152078.5 0.293 SLC30A4/ENSG00000104154.5 0.291 TTC18/ENSG00000156042.13 0.289 ABT1/ENSG00000146109.3 0.287 CEP70/ENSG00000114107.4 0.285 PLEKHB1/ENSG00000021300.9 0.281 PPIL1/ENSG00000137168.7 0.279 WIPF3/ENSG00000122574.6 0.279 CNR1/ENSG00000118432.11 0.276 CCDC88A/ENSG00000115355.11 0.274 BACE1/ENSG00000186318.11 0.273 RASSF6/ENSG00000169435.9 0.273 HSPB11/ENSG00000081870.6 0.273 HADHB/ENSG00000138029.9 0.27 PMM1/ENSG00000100417.7 0.27 LSMD1/ENSG00000183011.9 0.27 HMGCL/ENSG00000117305.10 0.269 LIN28A/ENSG00000131914.6 0.268 NPY/ENSG00000122585.3 0.267 CKAP2/ENSG00000136108.10 0.266 BSCL2/ENSG00000168000.10 0.266 RP4-742J24.2/ENSG00000236526.1 0.265 ELL2/ENSG00000118985.10 0.264 SPTLC3/ENSG00000172296.8 0.263 CTAGE5/ENSG00000150527.12 0.262 TET2/ENSG00000168769.8 0.259 BAMBI/ENSG00000095739.7 0.258 UNC5D/ENSG00000156687.6 0.257 PLD1/ENSG00000075651.11 0.257 NME7/ENSG00000143156.9 0.256 RPGR/ENSG00000156313.8 0.255 DPPA4/ENSG00000121570.8 0.253 PLCXD2/ENSG00000240891.2 0.253 PTGIS/ENSG00000124212.5 0.253 KANSL3/ENSG00000114982.13 Overrepresented GO terms in EP #14: Term Pvalue movement of cell or subcellular component 2.31E-05 high-density lipoprotein particle assembly 0.000176576 epithelial cell differentiation 0.000228775 glutathione derivative biosynthetic process 0.000271541 protein-lipid complex assembly 0.000352253 retinoid metabolic process 0.000741979 cell migration 0.001172435 enzyme linked receptor protein signaling pathway 0.001396476 heart development 0.001951347 acute inflammatory response 0.002205626 reverse cholesterol transport 0.002356737 negative regulation of cellular process 0.002493099 terpenoid metabolic process 0.00294797 response to stimulus 0.002991734 plasma lipoprotein particle organization 0.00306579 localization of cell 0.003210903 carboxylic acid catabolic process 0.003403835 signal transduction 0.003792828 response to organic substance 0.004495723 negative regulation of proteolysis 0.004831867 single-multicellular organism process 0.004858498 single-organism cellular process 0.005322566 negative regulation of endopeptidase activity 0.006380073 cell projection organization 0.006576839 cellular response to endogenous stimulus 0.006647047 positive regulation of polarized epithelial cell differentiation 0.007375132 negative regulation of anti-Mullerian hormone signaling pathway 0.007375132 kidney development 0.0074153 tissue development 0.007449355 negative regulation of hydrolase activity 0.008239601 high-density lipoprotein particle clearance 0.008260416 locomotion 0.009225173 urogenital system development 0.01081697 single-organism developmental process 0.015322551 cellular response to growth factor stimulus 0.015502831 negative regulation of blood coagulation 0.015989907 regulation of catalytic activity 0.018645131 retina development in camera-type eye 0.019558284 regulation of peptidase activity 0.021157716 regulation of cell communication 0.0218487 negative regulation of very-low-density lipoprotein particle remodeling 0.021915743 cellular response to chemical stimulus 0.021942498 eye morphogenesis 0.022780759 maternal placenta development 0.023167086 small molecule catabolic process 0.025029162 negative regulation of immune system process 0.026525483 phospholipid efflux 0.026955746 negative regulation of response to external stimulus 0.027206102 digestive system development 0.027730733 cellular component morphogenesis 0.028481619 tube development 0.029305317 regulation of plasma lipoprotein particle levels 0.034230664 lipid modification 0.03435688 regulation of stem cell differentiation 0.034425219 regulation of signaling 0.034973165 regulation of cellular response to growth factor stimulus 0.03680982 glutathione metabolic process 0.040546408 high-density lipoprotein particle remodeling 0.041985275 negative regulation of gliogenesis 0.043778759 regulation of lipid metabolic process 0.044366937 actin filament-based process 0.048584195 lipid catabolic process 0.048691167 regulation of multicellular organismal development 0.049597584 --------------------------------------------- "EP #15: 110 cells, 268 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0, stage5_: 0.28125, stage6.2_: 0.414634146341463, stage6.7_: 0.407894736842105, stage6.14_: 0.402985074626866, " Top Genes: 2.386 TPH1/ENSG00000129167.5 2.33 RP11-551L14.1/ENSG00000177359.13 2.097 PRPS2/ENSG00000101911.8 1.774 DNAJC12/ENSG00000108176.9 1.592 S100A11/ENSG00000163191.5 1.554 SPINK1/ENSG00000164266.6 1.545 ARHGAP24/ENSG00000138639.13 1.483 ID3/ENSG00000117318.8 1.456 PITHD1/ENSG00000057757.5 1.349 FXYD2/ENSG00000137731.8 1.344 EVL/ENSG00000196405.8 1.285 PLAC8/ENSG00000145287.6 1.22 MME/ENSG00000196549.6 1.206 CHGB/ENSG00000089199.5 1.202 HEPACAM2/ENSG00000188175.5 1.179 COL5A2/ENSG00000204262.7 1.174 VSTM2A/ENSG00000170419.6 1.159 RAB3C/ENSG00000152932.6 1.157 SLC18A1/ENSG00000036565.10 1.145 ADH6/ENSG00000172955.13 1.126 ZDHHC8P1/ENSG00000133519.8 1.106 NELL1/ENSG00000165973.13 1.101 PSME4/ENSG00000068878.10 1.045 SYT13/ENSG00000019505.3 1.037 PAPSS2/ENSG00000198682.8 1.005 FAM5C/ENSG00000162670.7 0.988 LXN/ENSG00000079257.3 0.983 ADH5/ENSG00000197894.6 0.983 LMX1A/ENSG00000162761.10 0.968 USH1C/ENSG00000006611.10 0.959 FBXW7/ENSG00000109670.9 0.953 NTM/ENSG00000182667.10 0.948 ID1/ENSG00000125968.7 0.944 KCNJ3/ENSG00000162989.3 0.94 QDPR/ENSG00000151552.7 0.924 NFKBIZ/ENSG00000144802.7 0.918 CTC-340A15.2/ENSG00000241956.5 0.897 CBLN1/ENSG00000102924.7 0.89 CD74/ENSG00000019582.10 0.872 AC140481.1/ENSG00000178162.4 0.863 GRIA4/ENSG00000152578.8 0.861 JAK1/ENSG00000162434.7 0.857 FEV/ENSG00000163497.2 0.855 ADAMTS9/ENSG00000163638.9 0.854 MGAT4A/ENSG00000071073.6 0.842 GPC3/ENSG00000147257.9 0.84 MGST3/ENSG00000143198.7 0.837 C9ORF3/ENSG00000148120.10 0.832 SCARNA22/ENSG00000249784.1 0.828 IGFBP3/ENSG00000146674.10 0.82 TTC29/ENSG00000137473.13 0.802 VPS41/ENSG00000006715.11 0.794 ANXA4/ENSG00000196975.9 0.79 AC133106.2/ENSG00000228073.1 0.787 ASS1/ENSG00000130707.13 0.774 MGLL/ENSG00000074416.9 0.773 NPY1R/ENSG00000164128.2 0.773 NR3C1/ENSG00000113580.10 0.761 MPP1/ENSG00000130830.9 0.753 MBNL2/ENSG00000139793.14 0.747 GCLC/ENSG00000001084.6 0.746 PARP1/ENSG00000143799.8 0.746 STC1/ENSG00000159167.7 0.729 NAGK/ENSG00000124357.7 0.719 ALCAM/ENSG00000170017.8 0.713 CCNY/ENSG00000108100.13 0.705 HDAC9/ENSG00000048052.16 0.699 ID2/ENSG00000115738.5 0.692 RGS2/ENSG00000116741.6 0.691 HIF1A/ENSG00000100644.12 0.689 MGST2/ENSG00000085871.4 0.688 CPEB4/ENSG00000113742.8 0.685 ARPP21/ENSG00000172995.12 0.685 "AKAP2,PALM2-AKAP2/ENSG00000241978.5" 0.669 KRT19/ENSG00000171345.9 0.668 PPAPDC1B/ENSG00000147535.12 0.661 ACSF2/ENSG00000167107.8 0.65 CTD-2003C8.1/ENSG00000247271.2 0.647 SSTR1/ENSG00000139874.5 0.642 CXXC5/ENSG00000171604.7 0.634 PALM2/ENSG00000243444.3 0.63 VDAC1/ENSG00000213585.6 0.628 CCS/ENSG00000173992.4 0.626 LGALS2/ENSG00000100079.5 0.619 RP11-547I7.2/ENSG00000237457.2 0.616 RP11-127I20.4/ENSG00000267795.1 0.607 SNAP25/ENSG00000132639.8 0.606 GCG/ENSG00000115263.10 0.6 PKIB/ENSG00000135549.8 0.6 SCN3A/ENSG00000153253.10 0.6 ARPP19/ENSG00000128989.6 0.599 DACH1/ENSG00000165659.12 0.593 ANKS1B/ENSG00000185046.14 0.591 NEFM/ENSG00000104722.9 0.588 SPATA20/ENSG00000006282.14 0.58 ABLIM1/ENSG00000099204.14 0.578 RP1-56K13.3/ENSG00000265784.1 0.577 CTSB/ENSG00000164733.16 0.576 TRIM2/ENSG00000109654.10 0.57 PAH/ENSG00000171759.4 0.569 NEBL/ENSG00000078114.14 0.565 SH3YL1/ENSG00000035115.17 0.564 FSTL4/ENSG00000053108.12 0.562 TBRG1/ENSG00000154144.8 0.559 FAM49B/ENSG00000153310.14 0.554 EPB41L3/ENSG00000082397.11 0.549 TSPAN5/ENSG00000168785.3 0.541 UBE2E3/ENSG00000170035.11 0.539 ADRA2A/ENSG00000150594.5 0.539 ZNF711/ENSG00000147180.12 0.538 TDP2/ENSG00000111802.9 0.534 AMER3/ENSG00000178171.6 0.521 C11ORF92/ENSG00000196167.5 0.518 AL590714.1/ENSG00000268387.1 0.518 SCG2/ENSG00000171951.4 0.516 PDE4D/ENSG00000113448.12 0.515 SNX14/ENSG00000135317.8 0.514 ASCL1/ENSG00000139352.3 0.506 CYSTM1/ENSG00000120306.5 0.506 HGD/ENSG00000113924.7 0.497 ARHGAP5/ENSG00000100852.8 0.497 PCSK1/ENSG00000175426.6 0.492 MOB1B/ENSG00000173542.4 0.49 WSB2/ENSG00000176871.4 0.488 KCTD12/ENSG00000178695.4 0.485 RP11-254I22.3/ENSG00000249746.1 0.484 C3ORF58/ENSG00000181744.4 0.481 PTPRM/ENSG00000173482.12 0.48 RPE/ENSG00000197713.10 0.478 DDC/ENSG00000132437.13 0.477 RHEB/ENSG00000106615.5 0.477 CEACAM1/ENSG00000079385.17 0.476 SAAL1/ENSG00000166788.5 0.474 PLCG2/ENSG00000197943.5 0.472 ZPLD1/ENSG00000170044.4 0.471 ERRFI1/ENSG00000116285.8 0.465 FAM134B/ENSG00000154153.9 0.464 CXCL12/ENSG00000107562.12 0.457 DPP10/ENSG00000175497.12 0.442 PPCS/ENSG00000127125.7 0.441 SLC38A1/ENSG00000111371.11 0.441 EFNA5/ENSG00000184349.8 0.438 RAB38/ENSG00000123892.7 0.437 UBR3/ENSG00000144357.12 0.437 CA2/ENSG00000104267.5 0.434 ARHGAP18/ENSG00000146376.6 0.434 CAMK2D/ENSG00000145349.12 0.433 RP11-21F16.1/ENSG00000267586.2 0.427 PON1/ENSG00000005421.4 0.427 RP11-56G10.2/ENSG00000257386.1 0.427 RP11-491F9.1/ENSG00000260614.1 0.426 SUMF2/ENSG00000129103.13 0.423 ANPEP/ENSG00000166825.9 0.422 RP11-17M24.1/ENSG00000265356.1 0.415 MSRA/ENSG00000175806.10 0.414 RPGR/ENSG00000156313.8 0.412 CD68/ENSG00000129226.9 0.411 HIPK2/ENSG00000064393.11 0.41 GRAMD3/ENSG00000155324.5 0.407 ITIH1/ENSG00000055957.6 0.407 SAMSN1/ENSG00000155307.13 0.404 CTNNA2/ENSG00000066032.13 0.403 PIP5K1B/ENSG00000107242.13 0.402 TTR/ENSG00000118271.5 0.402 PPM1G/ENSG00000115241.9 0.401 SEPHS2/ENSG00000179918.15 0.399 FAM126A/ENSG00000122591.7 0.399 CNTNAP2/ENSG00000174469.13 0.398 CCDC50/ENSG00000152492.9 0.398 ERBB3/ENSG00000065361.10 0.396 ABHD3/ENSG00000158201.5 0.396 PRR13/ENSG00000205352.6 0.392 TNFSF10/ENSG00000121858.6 0.392 INIP/ENSG00000148153.9 0.392 RNASE4/ENSG00000181784.11 0.39 EMB/ENSG00000170571.7 0.389 GNB1/ENSG00000078369.12 0.389 TUG1/ENSG00000253352.4 0.388 UBAC2/ENSG00000134882.11 0.387 PARP9/ENSG00000138496.12 0.386 RP1-60O19.1/ENSG00000235142.2 0.385 MT1F/ENSG00000198417.5 0.385 VAMP8/ENSG00000118640.6 0.384 SLC8A1-AS1/ENSG00000227028.2 0.384 EIF2AK1/ENSG00000086232.8 0.381 AC140481.7/ENSG00000240253.1 0.38 AC004540.4/ENSG00000225792.1 0.379 RNF220/ENSG00000187147.12 0.375 LDHA/ENSG00000134333.9 0.373 C2ORF54/ENSG00000172478.13 0.367 DIO1/ENSG00000211452.6 0.364 ADCY2/ENSG00000078295.11 0.363 RP1-34H18.1/ENSG00000231121.2 0.36 TMED3/ENSG00000166557.8 0.357 INHBA/ENSG00000122641.9 0.357 ADAMTSL3/ENSG00000156218.8 0.356 APPL1/ENSG00000157500.6 0.354 TAX1BP1/ENSG00000106052.8 0.35 PDK4/ENSG00000004799.7 0.35 PCSK2/ENSG00000125851.5 0.347 RAB13/ENSG00000143545.4 0.346 EIF4E2/ENSG00000135930.9 0.344 RP11-329L6.1/ENSG00000266402.1 0.343 ABCC3/ENSG00000108846.11 0.343 B2M/ENSG00000166710.12 0.34 RTN4IP1/ENSG00000130347.8 0.34 CDHR3/ENSG00000128536.11 0.339 RPA3/ENSG00000106399.7 0.338 RNF5/ENSG00000204308.6 0.336 STRADB/ENSG00000082146.8 0.335 GLIS3/ENSG00000107249.17 0.335 SPATA13/ENSG00000182957.10 0.332 CRYBB1/ENSG00000100122.5 0.33 LPP/ENSG00000145012.8 0.328 RP11-384F7.2/ENSG00000239268.2 0.326 LAP3/ENSG00000002549.7 0.322 RNASE4/ENSG00000258818.1 0.318 CNFN/ENSG00000105427.5 0.31 CAST/ENSG00000153113.18 0.309 NUDT2/ENSG00000164978.13 0.308 RP11-96H19.1/ENSG00000257261.1 0.308 MDP1/ENSG00000213920.4 0.308 ACOX2/ENSG00000168306.8 0.307 LCORL/ENSG00000178177.9 0.297 GCNT2/ENSG00000111846.11 0.295 ANKZF1/ENSG00000163516.9 0.293 ACSL1/ENSG00000151726.9 0.292 SNTG1/ENSG00000147481.9 0.291 STX7/ENSG00000079950.8 0.291 TBC1D1/ENSG00000065882.11 0.288 SH3GLB1/ENSG00000097033.10 0.287 SLC43A3/ENSG00000134802.12 0.283 PDZRN3/ENSG00000121440.10 0.283 ZMAT4/ENSG00000165061.10 0.282 SERPINB6/ENSG00000124570.13 0.281 RP1-163G9.1/ENSG00000177133.5 0.278 CMIP/ENSG00000153815.11 0.276 JAKMIP1/ENSG00000152969.12 0.275 KCNS3/ENSG00000170745.7 0.274 TMEFF2/ENSG00000144339.7 0.274 VCAN/ENSG00000038427.11 0.274 RP11-413B19.2/ENSG00000257228.1 0.274 ZC3HAV1/ENSG00000105939.8 0.273 PLS3/ENSG00000102024.11 0.273 SCO2/ENSG00000130489.8 0.271 C3ORF14/ENSG00000114405.6 0.271 RP11-3N13.2/ENSG00000254043.1 0.271 RP11-696N14.1/ENSG00000246090.2 0.27 MUT/ENSG00000146085.7 0.267 RP11-119F19.2/ENSG00000226381.3 0.267 SEBOX/ENSG00000109072.7 0.266 PSMD2/ENSG00000175166.12 0.265 SLC37A4/ENSG00000137700.11 0.265 MOSPD2/ENSG00000130150.7 0.264 CTSC/ENSG00000109861.11 0.263 HDAC3/ENSG00000171720.4 0.263 MRPL35/ENSG00000132313.10 0.261 RHOU/ENSG00000116574.4 0.26 FKBP11/ENSG00000134285.6 0.258 PTCHD4/ENSG00000244694.3 0.257 INSM1/ENSG00000173404.3 0.257 ATF7/ENSG00000170653.14 0.256 NEUROD4/ENSG00000123307.3 0.256 ITPR1/ENSG00000150995.13 0.256 MESP1/ENSG00000166823.5 0.255 S100A6/ENSG00000197956.5 0.251 TMEM66/ENSG00000133872.9 0.251 SHOC2/ENSG00000108061.7 Overrepresented GO terms in EP #15: Term Pvalue cellular response to organonitrogen compound 0.001610636 response to stimulus 0.002861835 response to nitrogen compound 0.00304484 response to peptide 0.004309854 regulation of homeostatic process 0.005967051 hemoglobin biosynthetic process 0.0064598 regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway 0.0064598 cellular response to oxygen-containing compound 0.006498187 adrenal chromaffin cell differentiation 0.008158442 cellular response to peptide hormone stimulus 0.009514652 cellular response to follicle-stimulating hormone stimulus 0.013536205 system process 0.018103286 L-phenylalanine catabolic process 0.018405481 cellular developmental process 0.019487745 response to hormone 0.019597288 response to glucagon 0.022292422 regulation of plasma membrane organization 0.023282591 noradrenergic neuron development 0.024231314 serotonin biosynthetic process 0.024231314 epithelial cell differentiation involved in mammary gland alveolus development 0.024231314 negative regulation of endodermal cell differentiation 0.024231314 T cell mediated cytotoxicity 0.024263193 regulation of transport 0.027436665 neurogenesis 0.027507416 neuron differentiation 0.029422378 developmental process 0.029751137 small molecule metabolic process 0.029997669 neuron apoptotic process 0.030956189 epithelial cell differentiation 0.038572435 neuron death in response to oxidative stress 0.039267052 aminergic neurotransmitter loading into synaptic vesicle 0.047980055 negative regulation of B cell differentiation 0.047980055 indolalkylamine biosynthetic process 0.047980055 voluntary musculoskeletal movement 0.047980055 protein localization to juxtaparanode region of axon 0.047980055 negative regulation of hepatocyte proliferation 0.047980055 --------------------------------------------- "EP #16: 227 cells, 298 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.157142857142857, St4_3_: 0.540229885057471, stage4: 0.557142857142857, St5_3_: 0.356164383561644, stage5_: 0.703125, stage6.2_: 0.402439024390244, stage6.7_: 0.131578947368421, stage6.14_: 0.238805970149254, " Top Genes: 2.523 HEPACAM2/ENSG00000188175.5 1.879 DCX/ENSG00000077279.12 1.856 NNAT/ENSG00000053438.7 1.727 MEIS1/ENSG00000143995.14 1.604 RGS4/ENSG00000117152.9 1.595 CADPS/ENSG00000163618.13 1.457 GCA/ENSG00000115271.6 1.343 RUNX1T1/ENSG00000079102.12 1.317 MLLT11/ENSG00000213190.2 1.277 UCP2/ENSG00000175567.3 1.272 CXXC4/ENSG00000168772.9 1.26 RP11-5A11.1/ENSG00000255105.1 1.204 SEZ6L/ENSG00000100095.14 1.204 CDKN1C/ENSG00000129757.8 1.181 LINC00643/ENSG00000186369.5 1.141 NREP/ENSG00000134986.9 1.134 SEC11C/ENSG00000166562.4 1.12 SOX11/ENSG00000176887.5 1.109 ARRDC3/ENSG00000113369.4 1.096 RABGAP1L/ENSG00000152061.17 1.077 C10ORF82/ENSG00000165863.12 1.049 MDK/ENSG00000110492.11 1.048 ELAVL4/ENSG00000162374.12 1.045 GHRL/ENSG00000157017.11 1.031 GDAP1/ENSG00000104381.8 1.029 LINC00261/ENSG00000259974.1 1.012 CD200/ENSG00000091972.13 1.006 CACNB2/ENSG00000165995.14 0.995 GABARAPL2/ENSG00000034713.3 0.98 GUSBP3/ENSG00000253203.2 0.98 FAM214A/ENSG00000047346.8 0.965 RIMS2/ENSG00000176406.16 0.962 RP11-136K7.2/ENSG00000250387.2 0.958 TAGLN3/ENSG00000144834.8 0.954 PTBP2/ENSG00000117569.13 0.943 RBP1/ENSG00000114115.5 0.941 STARD3NL/ENSG00000010270.9 0.932 DPP10/ENSG00000175497.12 0.911 PMCHL2/ENSG00000169040.10 0.903 FMNL2/ENSG00000157827.15 0.902 PAM/ENSG00000145730.16 0.896 PTPRS/ENSG00000105426.10 0.881 DCC/ENSG00000187323.7 0.875 TRA2A/ENSG00000164548.6 0.874 SRPRB/ENSG00000144867.6 0.868 MOB1B/ENSG00000173542.4 0.866 TUBB3/ENSG00000258947.2 0.856 RPAIN/ENSG00000129197.10 0.844 PLD3/ENSG00000105223.14 0.826 MAP2/ENSG00000078018.15 0.824 REEP3/ENSG00000165476.8 0.823 RP11-974F13.6/ENSG00000250763.1 0.821 AASS/ENSG00000008311.10 0.815 MAP1B/ENSG00000131711.10 0.812 ING3/ENSG00000071243.11 0.796 PRKAR1A/ENSG00000108946.8 0.789 CDKAL1/ENSG00000145996.7 0.785 C10ORF35/ENSG00000171224.7 0.773 KCNK17/ENSG00000124780.9 0.764 CTC-340A15.2/ENSG00000241956.5 0.748 FSTL5/ENSG00000168843.9 0.747 SMARCA2/ENSG00000080503.15 0.729 TRIM36-IT1/ENSG00000250472.1 0.722 RBFOX2/ENSG00000100320.18 0.705 CBFA2T2/ENSG00000078699.16 0.705 C9ORF16/ENSG00000171159.4 0.701 SLC38A3/ENSG00000188338.10 0.698 C7/ENSG00000112936.14 0.689 DCAF13/ENSG00000164934.9 0.684 LRRC42/ENSG00000116212.10 0.682 CTTN/ENSG00000085733.11 0.681 GSTA4/ENSG00000170899.6 0.672 RP11-1023L17.1/ENSG00000215158.5 0.665 LPPR1/ENSG00000148123.10 0.663 PPP3CA/ENSG00000138814.12 0.661 DNAJC12/ENSG00000108176.9 0.656 CCDC23/ENSG00000177868.7 0.653 ARF5/ENSG00000004059.6 0.651 PRICKLE2/ENSG00000163637.7 0.644 TP53INP1/ENSG00000164938.9 0.64 GUSBP9/ENSG00000215630.5 0.631 TOX/ENSG00000198846.5 0.623 SHISA2/ENSG00000180730.4 0.623 TFDP2/ENSG00000114126.13 0.62 DACH1/ENSG00000165659.12 0.617 RND3/ENSG00000115963.9 0.615 MARCKS/ENSG00000155130.5 0.613 PTS/ENSG00000150787.3 0.609 JKAMP/ENSG00000050130.13 0.607 MRPS9/ENSG00000135972.4 0.604 MYH10/ENSG00000133026.8 0.601 TSG101/ENSG00000074319.8 0.6 TES/ENSG00000135269.13 0.592 RFX3/ENSG00000080298.11 0.586 DCTN3/ENSG00000137100.11 0.578 BTG1/ENSG00000133639.3 0.571 DHRS7/ENSG00000100612.9 0.569 PAX4/ENSG00000106331.10 0.567 RP11-98J23.2/ENSG00000198237.7 0.566 RQCD1/ENSG00000144580.9 0.566 FLRT3/ENSG00000125848.9 0.566 BNIP3L/ENSG00000104765.10 0.564 DIRAS3/ENSG00000162595.4 0.557 FLRT2/ENSG00000185070.6 0.553 CCDC90B/ENSG00000137500.5 0.548 ZNF330/ENSG00000109445.6 0.545 SYT4/ENSG00000132872.7 0.541 SKAP2/ENSG00000005020.8 0.539 C18ORF32/ENSG00000177576.6 0.536 RAP2B/ENSG00000181467.2 0.532 SEC62/ENSG00000008952.12 0.532 ZNF93/ENSG00000184635.9 0.531 FKBP1A/ENSG00000088832.10 0.53 GUSBP1/ENSG00000183666.11 0.525 TSPAN2/ENSG00000134198.5 0.518 CRMP1/ENSG00000072832.10 0.516 FAM126A/ENSG00000122591.7 0.513 SOX5/ENSG00000134532.11 0.506 MED27/ENSG00000160563.8 0.505 RTN1/ENSG00000139970.12 0.505 MAD2L2/ENSG00000116670.10 0.502 LRRC49/ENSG00000137821.7 0.498 HDAC2/ENSG00000196591.7 0.494 DNM1L/ENSG00000087470.13 0.493 TSPAN6/ENSG00000000003.10 0.492 GNB1/ENSG00000078369.12 0.492 SERPINI1/ENSG00000163536.8 0.487 AMER3/ENSG00000178171.6 0.485 CADM1/ENSG00000182985.11 0.478 NECAP1/ENSG00000089818.12 0.475 C1ORF56/ENSG00000143443.9 0.475 RP11-1415C14.4/ENSG00000254701.2 0.473 AP3S1/ENSG00000177879.10 0.472 BCAR3/ENSG00000137936.12 0.469 LIG4/ENSG00000174405.9 0.469 RASSF6/ENSG00000169435.9 0.462 CPE/ENSG00000109472.9 0.462 KAT6B/ENSG00000156650.8 0.46 FAM105A/ENSG00000145569.5 0.46 AGO1/ENSG00000092847.6 0.456 FRMD4B/ENSG00000114541.10 0.451 CTC-524C5.2/ENSG00000263272.1 0.451 PHTF1/ENSG00000116793.11 0.448 VBP1/ENSG00000155959.6 0.445 ETV1/ENSG00000006468.9 0.442 TBCC/ENSG00000124659.5 0.442 FGD4/ENSG00000139132.10 0.441 DLG5/ENSG00000151208.12 0.441 SGCD/ENSG00000170624.9 0.439 PEG10/ENSG00000242265.1 0.439 NEUROD1/ENSG00000162992.3 0.435 RMST/ENSG00000255794.2 0.431 RAP1GAP2/ENSG00000132359.9 0.431 ACTR1A/ENSG00000138107.7 0.43 FOXP2/ENSG00000128573.18 0.43 TUBB/ENSG00000196230.8 0.43 HIST1H2BK/ENSG00000197903.6 0.427 SSTR2/ENSG00000180616.4 0.426 FBXO8/ENSG00000164117.8 0.422 SRP9P1/ENSG00000180581.6 0.421 TPP2/ENSG00000134900.7 0.42 SNRPB2/ENSG00000125870.6 0.419 TBPL1/ENSG00000028839.4 0.417 DCTN2/ENSG00000175203.11 0.416 TMSB4X/ENSG00000205542.6 0.413 MSN/ENSG00000147065.11 0.409 FUT8/ENSG00000033170.12 0.408 TXLNA/ENSG00000084652.11 0.407 ACOT7/ENSG00000097021.14 0.404 ABCA1/ENSG00000165029.11 0.403 CFL2/ENSG00000165410.10 0.402 ACADM/ENSG00000117054.9 0.401 PRMT1/ENSG00000126457.16 0.4 RAPGEF4/ENSG00000091428.13 0.398 SPAG9/ENSG00000008294.16 0.395 PELI2/ENSG00000139946.5 0.393 USP22/ENSG00000124422.7 0.392 ENPP2/ENSG00000136960.8 0.391 PROX1/ENSG00000117707.10 0.391 SPAG7/ENSG00000091640.3 0.39 RP11-469M7.1/ENSG00000260006.1 0.388 CCDC88A/ENSG00000115355.11 0.385 RAB7A/ENSG00000075785.8 0.384 ROBO1/ENSG00000169855.15 0.382 MEIS2/ENSG00000134138.14 0.382 MRPL9/ENSG00000143436.6 0.379 AAED1/ENSG00000158122.7 0.379 RFX6/ENSG00000185002.5 0.379 VWA5B2/ENSG00000145198.10 0.377 F10/ENSG00000126218.7 0.372 NOSIP/ENSG00000142546.9 0.369 TTTY15/ENSG00000233864.3 0.367 TNFRSF21/ENSG00000146072.6 0.365 MMP16/ENSG00000156103.11 0.365 SRP72/ENSG00000174780.11 0.364 SMARCAD1/ENSG00000163104.13 0.359 AL365202.1/ENSG00000203286.4 0.355 CACUL1/ENSG00000151893.10 0.353 FAM110B/ENSG00000169122.7 0.352 MPHOSPH9/ENSG00000051825.9 0.35 PAPOLG/ENSG00000115421.8 0.348 CEP41/ENSG00000106477.13 0.348 PDGFA/ENSG00000197461.9 0.347 PEX19/ENSG00000162735.13 0.344 APPL2/ENSG00000136044.7 0.343 PLK1S1/ENSG00000088970.11 0.342 ABHD13/ENSG00000139826.5 0.339 RP11-268I9.1/ENSG00000243303.1 0.338 WDR45/ENSG00000196998.10 0.336 KIF5A/ENSG00000155980.7 0.334 DYNLT1/ENSG00000146425.6 0.333 KLC1/ENSG00000126214.16 0.328 BTBD3/ENSG00000132640.10 0.328 SRSF3/ENSG00000112081.11 0.328 RGS9/ENSG00000108370.11 0.327 HID1/ENSG00000167861.11 0.327 EFCAB2/ENSG00000203666.8 0.322 COPE/ENSG00000105669.8 0.321 RPS6KB1/ENSG00000108443.9 0.32 NDUFA9/ENSG00000139180.5 0.32 WEE1/ENSG00000166483.6 0.318 KALRN/ENSG00000160145.10 0.318 TTC8/ENSG00000165533.14 0.317 RP11-358L16.2/ENSG00000242639.2 0.316 GRB2/ENSG00000177885.9 0.315 MICAL1/ENSG00000135596.13 0.315 ENY2/ENSG00000120533.8 0.311 SNX24/ENSG00000064652.6 0.31 RP11-395P17.3/ENSG00000234771.2 0.309 HECW2/ENSG00000138411.5 0.307 DMAP1/ENSG00000178028.9 0.306 PDE6D/ENSG00000156973.9 0.304 TRAF3IP2/ENSG00000056972.14 0.303 GIPR/ENSG00000010310.4 0.303 PTER/ENSG00000165983.10 0.303 COQ4/ENSG00000167113.5 0.302 PPP1R3C/ENSG00000119938.8 0.302 NEO1/ENSG00000067141.12 0.302 NIPSNAP1/ENSG00000184117.7 0.301 SIM1/ENSG00000112246.5 0.299 TET2/ENSG00000168769.8 0.299 PCDH9/ENSG00000184226.10 0.298 AK1/ENSG00000106992.13 0.298 MLXIPL/ENSG00000009950.11 0.298 CTC-535M15.1/ENSG00000253512.1 0.295 GOLGA7/ENSG00000147533.12 0.295 C17ORF75/ENSG00000108666.5 0.294 BRD3/ENSG00000169925.12 0.293 AC007740.1/ENSG00000237750.2 0.292 AK9/ENSG00000155085.10 0.29 YPEL1/ENSG00000100027.10 0.287 ZFAND4/ENSG00000172671.15 0.287 RP11-83M16.5/ENSG00000249736.1 0.287 TMEM200A/ENSG00000164484.7 0.285 ERO1LB/ENSG00000086619.9 0.284 CHN1/ENSG00000128656.9 0.283 RP11-631F7.2/ENSG00000230205.1 0.282 SPTBN2/ENSG00000173898.7 0.282 RP11-82O19.2/ENSG00000265713.1 0.281 NKIRAS2/ENSG00000168256.13 0.281 PTPRK/ENSG00000152894.10 0.281 SLC35B1/ENSG00000121073.8 0.28 STXBP5L/ENSG00000145087.8 0.28 NAV3/ENSG00000067798.9 0.278 BPGM/ENSG00000172331.7 0.278 KCNH7/ENSG00000184611.7 0.277 THSD4/ENSG00000187720.10 0.276 WAC/ENSG00000095787.16 0.274 HARS/ENSG00000170445.8 0.274 TMEM196/ENSG00000173452.9 0.273 PDE9A/ENSG00000160191.13 0.272 INSM1/ENSG00000173404.3 0.271 KIT/ENSG00000157404.11 0.27 EML4/ENSG00000143924.14 0.267 ZNF195/ENSG00000005801.12 0.267 TRIM59/ENSG00000213186.3 0.267 SLC25A13/ENSG00000004864.9 0.266 ESRRG/ENSG00000196482.12 0.266 MATN2/ENSG00000132561.9 0.264 TMED8/ENSG00000100580.7 0.263 TSPAN5/ENSG00000168785.3 0.263 RP11-626E13.1/ENSG00000235902.1 0.263 CLCN3/ENSG00000109572.9 0.262 COPS4/ENSG00000138663.4 0.262 GLS/ENSG00000115419.8 0.261 GS1-251I9.4/ENSG00000253738.1 0.261 ZNF669/ENSG00000188295.10 0.259 RP5-1085F17.3/ENSG00000260257.1 0.259 ZSCAN2/ENSG00000176371.9 0.259 ATL1/ENSG00000198513.7 0.258 WSB2/ENSG00000176871.4 0.258 VPS72/ENSG00000163159.7 0.256 RASA4/ENSG00000105808.12 0.256 IRGQ/ENSG00000167378.4 0.255 RPS7P8/ENSG00000213183.3 0.255 ELL2/ENSG00000118985.10 0.254 CIRH1A/ENSG00000141076.12 0.252 RP11-499P20.2/ENSG00000240291.1 Overrepresented GO terms in EP #16: Term Pvalue generation of neurons 2.64E-07 neuron projection morphogenesis 7.81E-06 cell projection organization 1.23E-05 cell part morphogenesis 3.33E-05 cellular component organization or biogenesis 0.000172308 cell morphogenesis 0.000183643 axon guidance 0.000241051 cell morphogenesis involved in neuron differentiation 0.000271885 metencephalon development 0.000541028 pancreas development 0.000764516 central nervous system development 0.000841192 axon development 0.001686647 multicellular organism development 0.001914072 secretion by cell 0.001938025 single-organism process 0.002364766 pancreatic A cell differentiation 0.004887122 regulation of cell development 0.004894911 lens morphogenesis in camera-type eye 0.005943239 regulation of protein secretion 0.006152947 regulation of peptide hormone secretion 0.007485523 nervous system development 0.008529212 negative regulation of insulin secretion 0.009180225 regulation of peptide transport 0.009854717 single-organism organelle organization 0.010200047 amide transport 0.011502109 regulation of neuron differentiation 0.0121131 hormone secretion 0.014802773 negative regulation of peptide secretion 0.017098612 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.018899781 cell differentiation 0.02096004 protein transport 0.02333403 neuron development 0.02472262 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.026362959 cerebellar cortex development 0.02646385 anatomical structure morphogenesis 0.026616029 dendrite development 0.026886321 insulin processing 0.027344721 endocrine system development 0.027980327 glandular epithelial cell differentiation 0.032374105 locomotion 0.03921289 dentate gyrus development 0.046770007 small GTPase mediated signal transduction 0.046795376 positive regulation of nervous system development 0.047037979 --------------------------------------------- "EP #17: 772 cells, 751 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 1, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 1, St5_3_: 1, stage5_: 1, stage6.2_: 1, stage6.7_: 0.986842105263158, stage6.14_: 1, " Top Genes: 2.025 SOX4/ENSG00000124766.4 1.873 TTC3/ENSG00000182670.9 1.825 AKAP9/ENSG00000127914.12 1.796 DPYSL2/ENSG00000092964.11 1.792 PON2/ENSG00000105854.8 1.7 TIA1/ENSG00000116001.11 1.516 WSB1/ENSG00000109046.10 1.49 BRD8/ENSG00000112983.13 1.484 DNMT3A/ENSG00000119772.12 1.437 N4BP2L2/ENSG00000244754.4 1.357 CPNE1/ENSG00000214078.7 1.323 LAMB1/ENSG00000091136.9 1.299 BAZ2B/ENSG00000123636.13 1.294 SREK1/ENSG00000153914.11 1.28 RP11-252A24.7/ENSG00000260539.1 1.232 SCARNA22/ENSG00000249784.1 1.214 TMED4/ENSG00000158604.10 1.212 DSP/ENSG00000096696.9 1.209 GTF2I/ENSG00000077809.8 1.201 RP11-770J1.5/ENSG00000254873.1 1.2 RBM6/ENSG00000004534.10 1.199 PTPLAD1/ENSG00000074696.7 1.196 RSRC2/ENSG00000111011.13 1.165 RP11-349A22.5/ENSG00000257621.3 1.148 PCMTD1/ENSG00000168300.9 1.143 TMEM59/ENSG00000116209.7 1.142 ATRX/ENSG00000085224.16 1.136 CTNND1/ENSG00000198561.8 1.121 TSC22D1/ENSG00000102804.10 1.11 RBM39/ENSG00000131051.15 1.1 CD46/ENSG00000117335.14 1.096 RBM5/ENSG00000003756.12 1.09 CLK1/ENSG00000013441.11 1.084 DAAM1/ENSG00000100592.11 1.066 PNISR/ENSG00000132424.10 1.051 OCIAD2/ENSG00000145247.7 1.039 SMARCE1/ENSG00000073584.14 1.032 SRSF6/ENSG00000124193.10 1.026 KDM5B/ENSG00000117139.12 1.024 TCF12/ENSG00000140262.13 1.022 "RBM14-RBM4,RBM4/ENSG00000173933.15" 1.018 MLL5/ENSG00000005483.15 1.003 PIAS1/ENSG00000033800.9 0.994 CASP2/ENSG00000106144.15 0.992 HNRNPU/ENSG00000153187.12 0.991 DNAJA1/ENSG00000086061.11 0.989 BPTF/ENSG00000171634.12 0.958 ARID2/ENSG00000189079.11 0.94 CCNL1/ENSG00000163660.7 0.939 PCBD1/ENSG00000166228.4 0.935 BZW1/ENSG00000082153.13 0.934 CHD6/ENSG00000124177.10 0.931 PAN3/ENSG00000152520.9 0.923 FAM213A/ENSG00000122378.9 0.919 SMARCC2/ENSG00000139613.7 0.913 ITGB1/ENSG00000150093.14 0.91 ANKRD10/ENSG00000088448.10 0.908 CDK5RAP3/ENSG00000108465.9 0.904 RSRC1/ENSG00000174891.8 0.899 ATXN7L3B/ENSG00000253719.2 0.898 CACUL1/ENSG00000151893.10 0.897 PAFAH1B2/ENSG00000168092.9 0.886 CRBN/ENSG00000113851.9 0.886 TROVE2/ENSG00000116747.8 0.881 ZKSCAN1/ENSG00000106261.12 0.877 MYO6/ENSG00000196586.8 0.876 ANAPC13/ENSG00000129055.8 0.872 TNRC6B/ENSG00000100354.15 0.866 RBBP4/ENSG00000162521.13 0.865 PRKRA/ENSG00000180228.8 0.865 ZNF518A/ENSG00000177853.10 0.859 ERO1L/ENSG00000197930.8 0.856 ZC3H11A/ENSG00000058673.11 0.855 SDCCAG8/ENSG00000054282.11 0.854 YAE1D1/ENSG00000241127.3 0.851 IP6K2/ENSG00000068745.10 0.85 FNBP1L/ENSG00000137942.12 0.85 SRSF5/ENSG00000100650.11 0.839 ZMYM2/ENSG00000121741.11 0.836 ADNP/ENSG00000101126.10 0.835 USP33/ENSG00000077254.10 0.834 FOXP1/ENSG00000114861.14 0.832 C7ORF73/ENSG00000243317.3 0.83 SDCBP/ENSG00000137575.7 0.818 ETNK1/ENSG00000139163.11 0.817 UBA6/ENSG00000033178.7 0.814 DCAF8/ENSG00000132716.12 0.809 USP47/ENSG00000170242.13 0.809 PTBP2/ENSG00000117569.13 0.807 NDUFS2/ENSG00000158864.8 0.804 SERINC1/ENSG00000111897.5 0.801 APEX1/ENSG00000100823.7 0.799 UBE2B/ENSG00000119048.3 0.799 THRAP3/ENSG00000054118.9 0.797 THUMPD1/ENSG00000066654.8 0.794 ZNF3/ENSG00000166526.12 0.793 CBR4/ENSG00000145439.7 0.784 ERVK3-1/ENSG00000142396.5 0.782 C22ORF28/ENSG00000100220.7 0.778 CTB-89H12.4/ENSG00000230551.3 0.774 SLC39A9/ENSG00000029364.7 0.773 CEP95/ENSG00000258890.2 0.768 FAM32A/ENSG00000105058.7 0.765 RP11-15H20.5/ENSG00000269837.1 0.765 CNP/ENSG00000173786.11 0.754 MAPK1IP1L/ENSG00000168175.9 0.753 MDM4/ENSG00000198625.8 0.751 PBRM1/ENSG00000163939.14 0.75 BBIP1/ENSG00000214413.3 0.75 OCLN/ENSG00000197822.6 0.748 ZFR/ENSG00000056097.11 0.745 DDX3X/ENSG00000215301.5 0.743 SRSF11/ENSG00000116754.9 0.742 STRN3/ENSG00000196792.7 0.74 TNRC6A/ENSG00000090905.13 0.737 NPEPPS/ENSG00000141279.9 0.737 THYN1/ENSG00000151500.10 0.735 ADD1/ENSG00000087274.12 0.733 PPIP5K2/ENSG00000145725.13 0.732 PTPRF/ENSG00000142949.12 0.731 EXOC7/ENSG00000182473.15 0.726 PDS5B/ENSG00000083642.14 0.726 PHIP/ENSG00000146247.12 0.723 CHD1/ENSG00000153922.6 0.722 PAPD4/ENSG00000164329.9 0.721 ADH5/ENSG00000197894.6 0.716 RP11-488L18.10/ENSG00000259865.1 0.713 ACTL6A/ENSG00000136518.12 0.712 CLASP1/ENSG00000074054.13 0.711 MAP4K4/ENSG00000071054.11 0.709 PTOV1/ENSG00000104960.11 0.705 BCLAF1/ENSG00000029363.11 0.704 H3F3AP4/ENSG00000235655.2 0.702 RBPJ/ENSG00000168214.16 0.702 FAM133B/ENSG00000234545.3 0.701 TRIM13/ENSG00000204977.5 0.699 TPR/ENSG00000047410.8 0.693 COMMD3/ENSG00000148444.11 0.692 SLC30A7/ENSG00000162695.7 0.691 MARCH7/ENSG00000136536.9 0.69 GLTP/ENSG00000139433.5 0.688 PDCD4/ENSG00000150593.11 0.688 NXF1/ENSG00000162231.8 0.683 WHSC1L1/ENSG00000147548.11 0.681 R3HDM2/ENSG00000179912.15 0.681 RBMX/ENSG00000147274.10 0.676 SLU7/ENSG00000164609.5 0.669 GOLGB1/ENSG00000173230.11 0.668 ZNF738/ENSG00000172687.9 0.667 RWDD2B/ENSG00000156253.2 0.664 STAT2/ENSG00000170581.9 0.663 TGFBR1/ENSG00000106799.7 0.66 TUBGCP4/ENSG00000137822.8 0.659 RP11-56G10.2/ENSG00000257386.1 0.658 BDH2/ENSG00000164039.10 0.656 CNEP1R1/ENSG00000205423.7 0.651 UBR2/ENSG00000024048.6 0.651 UBXN4/ENSG00000144224.12 0.65 CCNDBP1/ENSG00000166946.9 0.648 TAF9B/ENSG00000187325.4 0.648 NELFCD/ENSG00000101158.8 0.646 SRPK2/ENSG00000135250.12 0.645 PBX1/ENSG00000185630.13 0.643 METTL17/ENSG00000165792.13 0.641 ZNF326/ENSG00000162664.11 0.641 HN1/ENSG00000189159.11 0.638 IST1/ENSG00000182149.14 0.638 ZNF33A/ENSG00000189180.11 0.637 RBM23/ENSG00000100461.13 0.636 DEDD/ENSG00000158796.11 0.634 NVL/ENSG00000143748.13 0.63 RP11-658F2.8/ENSG00000258297.1 0.629 PAIP1/ENSG00000172239.9 0.629 EAF1/ENSG00000144597.9 0.626 PNN/ENSG00000100941.4 0.623 ZNF644/ENSG00000122482.16 0.622 BBX/ENSG00000114439.14 0.621 CCDC104/ENSG00000163001.7 0.619 KIAA0232/ENSG00000170871.7 0.612 TARBP1/ENSG00000059588.5 0.611 HBP1/ENSG00000105856.8 0.608 DAZAP2/ENSG00000183283.10 0.607 SSBP2/ENSG00000145687.11 0.606 SKIL/ENSG00000136603.9 0.605 POLB/ENSG00000070501.7 0.605 SATB1/ENSG00000182568.11 0.602 NAA20/ENSG00000173418.7 0.6 SSBP3/ENSG00000157216.11 0.599 ODF2L/ENSG00000122417.11 0.596 KANSL2/ENSG00000139620.8 0.595 PAPSS1/ENSG00000138801.4 0.593 FARP1/ENSG00000152767.11 0.592 STRBP/ENSG00000165209.14 0.592 TRIM33/ENSG00000197323.6 0.592 ST13/ENSG00000100380.8 0.592 DHX9/ENSG00000135829.12 0.591 TSPYL1/ENSG00000189241.6 0.581 CDS2/ENSG00000101290.9 0.58 RP11-473I1.10/ENSG00000263244.1 0.578 DNAJB6/ENSG00000105993.10 0.575 BTF3L4/ENSG00000134717.13 0.575 SEC22B/ENSG00000223380.3 0.572 FBXO3/ENSG00000110429.9 0.572 DCAF7/ENSG00000136485.9 0.572 CAMK2D/ENSG00000145349.12 0.571 MRPL42/ENSG00000198015.8 0.571 NDUFA5/ENSG00000128609.10 0.57 RSF1/ENSG00000048649.9 0.57 EXOSC10/ENSG00000171824.9 0.567 HNRNPR/ENSG00000125944.13 0.567 ZNF91/ENSG00000167232.9 0.567 ACADVL/ENSG00000072778.15 0.566 FAM192A/ENSG00000172775.12 0.565 ZNF292/ENSG00000188994.8 0.565 MLLT10/ENSG00000078403.12 0.565 ZC2HC1A/ENSG00000104427.6 0.562 ERBB2IP/ENSG00000112851.10 0.562 C2ORF68/ENSG00000168887.6 0.561 DICER1/ENSG00000100697.10 0.561 NEDD4L/ENSG00000049759.12 0.557 MED23/ENSG00000112282.13 0.555 SMAD2/ENSG00000175387.11 0.555 RP1-40E16.11/ENSG00000228170.1 0.555 RARS2/ENSG00000146282.13 0.555 RB1CC1/ENSG00000023287.8 0.553 CNOT4/ENSG00000080802.14 0.552 CHD9/ENSG00000177200.11 0.552 PHACTR2/ENSG00000112419.10 0.551 ATF2/ENSG00000115966.12 0.55 MMADHC/ENSG00000168288.8 0.55 CCDC66/ENSG00000180376.12 0.55 CWC15/ENSG00000150316.7 0.549 MARCKS/ENSG00000155130.5 0.547 TERF1/ENSG00000147601.9 0.545 STAG3L4/ENSG00000106610.10 0.541 MLLT4/ENSG00000130396.16 0.54 PLXNB1/ENSG00000164050.8 0.54 PIP4K2A/ENSG00000150867.9 0.54 MEAF6/ENSG00000163875.11 0.539 ZNF260/ENSG00000254004.2 0.539 THAP5/ENSG00000177683.9 0.537 PUM1/ENSG00000134644.11 0.536 COPB1/ENSG00000129083.8 0.535 TMSB15B/ENSG00000158427.10 0.534 WDR48/ENSG00000114742.9 0.533 SCOC/ENSG00000153130.12 0.533 AP1G2/ENSG00000213983.7 0.532 UPF3B/ENSG00000125351.6 0.53 POLR2B/ENSG00000047315.10 0.528 SENP5/ENSG00000119231.6 0.527 LARP4B/ENSG00000107929.9 0.525 ING4/ENSG00000111653.15 0.524 ZNF84/ENSG00000198040.6 0.524 ZDHHC6/ENSG00000023041.7 0.519 PPP4R1/ENSG00000154845.11 0.517 ZNF286A/ENSG00000187607.11 0.516 SH3BGRL2/ENSG00000198478.6 0.516 LCOR/ENSG00000196233.7 0.516 C9ORF72/ENSG00000147894.10 0.515 DCAF5/ENSG00000139990.13 0.514 WDR19/ENSG00000157796.13 0.513 CBFB/ENSG00000067955.9 0.512 CCDC126/ENSG00000169193.7 0.512 HDGFRP3/ENSG00000166503.4 0.511 SERINC3/ENSG00000132824.9 0.511 RANBP9/ENSG00000010017.9 0.508 NIPBL/ENSG00000164190.12 0.506 UBA1/ENSG00000130985.12 0.505 ZNF664/ENSG00000179195.11 0.504 EXOSC6/ENSG00000223496.1 0.502 MRFAP1L1/ENSG00000178988.10 0.5 FYTTD1/ENSG00000122068.7 0.499 USP3/ENSG00000140455.12 0.499 PCNXL4/ENSG00000126773.8 0.499 YPEL5/ENSG00000119801.8 0.497 NCOA4/ENSG00000138293.15 0.497 KIAA1324L/ENSG00000164659.10 0.496 INSR/ENSG00000171105.9 0.496 MAP4K5/ENSG00000012983.7 0.495 KIAA1598/ENSG00000187164.13 0.493 MIER1/ENSG00000198160.10 0.493 PAXBP1/ENSG00000159086.10 0.492 IFT81/ENSG00000122970.11 0.492 FAM92A1/ENSG00000188343.8 0.491 PIK3R3/ENSG00000117461.10 0.49 PPIL4/ENSG00000131013.3 0.489 TM2D3/ENSG00000184277.8 0.488 USP9Y/ENSG00000114374.8 0.485 DDX3Y/ENSG00000067048.12 0.485 BAZ1B/ENSG00000009954.6 0.485 ZNF33B/ENSG00000196693.9 0.484 PHF14/ENSG00000106443.10 0.483 UBA3/ENSG00000144744.12 0.482 POGZ/ENSG00000143442.17 0.482 IRF2BP2/ENSG00000168264.6 0.48 SBNO1/ENSG00000139697.7 0.479 PSMD12/ENSG00000197170.5 0.479 GPATCH2/ENSG00000092978.6 0.477 TP53INP1/ENSG00000164938.9 0.475 PSMC1/ENSG00000100764.9 0.474 RAE1/ENSG00000101146.8 0.473 ZMYND8/ENSG00000101040.15 0.471 ZNF254/ENSG00000213096.5 0.471 C5ORF15/ENSG00000113583.6 0.471 IFT74/ENSG00000096872.11 0.471 CCDC23/ENSG00000177868.7 0.471 ZNF711/ENSG00000147180.12 0.47 FLJ20373/ENSG00000233404.2 0.47 PDS5A/ENSG00000121892.10 0.47 ZFX/ENSG00000005889.11 0.468 AES/ENSG00000104964.10 0.466 EYA3/ENSG00000158161.11 0.465 PTEN/ENSG00000171862.5 0.465 BRWD1/ENSG00000185658.9 0.464 CXADR/ENSG00000154639.14 0.464 RBBP6/ENSG00000122257.14 0.464 RBM7/ENSG00000076053.6 0.463 ZNF512/ENSG00000243943.4 0.462 ARID1A/ENSG00000117713.13 0.46 TMEM67/ENSG00000164953.11 0.457 CHMP1B/ENSG00000255112.2 0.456 COMMD1/ENSG00000173163.6 0.455 AHI1/ENSG00000135541.16 0.455 CCAR1/ENSG00000060339.9 0.455 ZC3H14/ENSG00000100722.14 0.454 ROCK1/ENSG00000067900.5 0.454 COMMD10/ENSG00000145781.4 0.453 FAM204A/ENSG00000165669.9 0.45 ATG13/ENSG00000175224.12 0.45 ABI2/ENSG00000138443.10 0.449 USP40/ENSG00000085982.9 0.449 AUP1/ENSG00000115307.12 0.447 PRKAA1/ENSG00000132356.7 0.445 NSD1/ENSG00000165671.14 0.444 RUFY3/ENSG00000018189.7 0.443 KANSL1/ENSG00000120071.8 0.443 CEP57/ENSG00000166037.6 0.443 CIRBP/ENSG00000099622.9 0.443 HDAC2/ENSG00000196591.7 0.442 CD164/ENSG00000135535.10 0.441 PAPOLA/ENSG00000090060.13 0.438 ZNF706/ENSG00000120963.7 0.437 TRA2B/ENSG00000136527.13 0.437 HNRPLL/ENSG00000143889.10 0.435 TMEM230/ENSG00000089063.10 0.433 BPHL/ENSG00000137274.8 0.431 DHRS7/ENSG00000100612.9 0.43 FNDC3A/ENSG00000102531.12 0.43 CASD1/ENSG00000127995.12 0.43 TRIP11/ENSG00000100815.8 0.43 ZNF562/ENSG00000171466.5 0.43 DYNC1I2/ENSG00000077380.11 0.43 SYS1/ENSG00000204070.5 0.428 COPB2/ENSG00000184432.4 0.428 SPATA7/ENSG00000042317.12 0.427 USP22/ENSG00000124422.7 0.424 PSIP1/ENSG00000164985.10 0.424 SRPK1/ENSG00000096063.10 0.423 MLLT11/ENSG00000213190.2 0.423 FBXO21/ENSG00000135108.10 0.423 CDH2/ENSG00000170558.4 0.423 PIBF1/ENSG00000083535.11 0.422 RUFY2/ENSG00000204130.8 0.422 DHX36/ENSG00000174953.9 0.421 CTBP2/ENSG00000175029.12 0.42 NR2C1/ENSG00000120798.11 0.419 ERC1/ENSG00000082805.14 0.419 IWS1/ENSG00000163166.9 0.419 PDRG1/ENSG00000088356.4 0.419 EIF5B/ENSG00000158417.5 0.418 GPATCH8/ENSG00000186566.7 0.417 VPS13C/ENSG00000129003.11 0.417 ZBED5/ENSG00000236287.3 0.416 CEP170/ENSG00000143702.11 0.415 NAA16/ENSG00000172766.14 0.415 MAPK10/ENSG00000109339.14 0.414 DECR1/ENSG00000104325.2 0.413 SPIN1/ENSG00000106723.12 0.413 RP11-344E13.3/ENSG00000233098.3 0.413 SENP7/ENSG00000138468.11 0.412 TMEM209/ENSG00000146842.12 0.411 RAB3D/ENSG00000105514.3 0.41 PSMD4/ENSG00000159352.10 0.41 CCT2/ENSG00000166226.7 0.409 MLL3/ENSG00000055609.13 0.409 TCEB3/ENSG00000011007.7 0.409 TP53BP1/ENSG00000067369.9 0.407 ARID4A/ENSG00000032219.14 0.405 SETD2/ENSG00000181555.15 0.405 MKL2/ENSG00000186260.12 0.404 CIR1/ENSG00000138433.11 0.404 DPF2/ENSG00000133884.5 0.402 PHLDB2/ENSG00000144824.15 0.402 TOX3/ENSG00000103460.12 0.401 GNPAT/ENSG00000116906.7 0.401 KIAA0146/ENSG00000164808.12 0.4 VPS41/ENSG00000006715.11 0.399 CREBBP/ENSG00000005339.8 0.399 PILRB/ENSG00000121716.13 0.398 C1ORF52/ENSG00000162642.9 0.398 ACIN1/ENSG00000100813.10 0.397 DYNC1LI2/ENSG00000135720.8 0.397 ATP6V0D1/ENSG00000159720.7 0.395 CDK13/ENSG00000065883.10 0.394 INSIG2/ENSG00000125629.10 0.393 ITM2C/ENSG00000135916.11 0.393 PPME1/ENSG00000214517.4 0.393 DYNC1LI1/ENSG00000144635.4 0.391 HELZ/ENSG00000198265.7 0.39 TAOK1/ENSG00000160551.5 0.389 CLIP1/ENSG00000130779.15 0.388 EXOC1/ENSG00000090989.13 0.388 ZNF24/ENSG00000172466.11 0.386 ATP13A3/ENSG00000133657.10 0.385 EFCAB14/ENSG00000159658.6 0.385 FAM127A/ENSG00000134590.9 0.384 EXOC5/ENSG00000070367.11 0.384 ZNF252P/ENSG00000196922.6 0.383 SUDS3/ENSG00000111707.7 0.383 VPS45/ENSG00000136631.8 0.383 MLF1/ENSG00000178053.13 0.383 ARL6IP5/ENSG00000144746.6 0.383 TMEM179B/ENSG00000185475.4 0.383 SUPT20H/ENSG00000102710.15 0.382 AASDHPPT/ENSG00000149313.6 0.382 KATNBL1/ENSG00000134152.6 0.381 NPIP/ENSG00000183426.11 0.381 CLK4/ENSG00000113240.8 0.381 IFT57/ENSG00000114446.4 0.38 ZNF140/ENSG00000196387.5 0.379 ANKZF1/ENSG00000163516.9 0.379 KRR1/ENSG00000111615.8 0.378 MED13/ENSG00000108510.5 0.378 RP11-283I3.6/ENSG00000261799.1 0.378 CUEDC2/ENSG00000107874.6 0.378 THAP6/ENSG00000174796.8 0.378 INTS3/ENSG00000143624.9 0.377 PIK3C3/ENSG00000078142.7 0.377 PHKB/ENSG00000102893.11 0.377 DCTN4/ENSG00000132912.8 0.377 FAM173B/ENSG00000150756.9 0.377 FOXA2/ENSG00000125798.9 0.376 MED17/ENSG00000042429.6 0.375 SEMA6A/ENSG00000092421.12 0.375 STK4/ENSG00000101109.7 0.374 CUX1/ENSG00000257923.4 0.373 GULP1/ENSG00000144366.11 0.373 ARFGAP2/ENSG00000149182.10 0.373 TTC21B/ENSG00000123607.10 0.372 SYNC/ENSG00000162520.10 0.372 GAPVD1/ENSG00000165219.17 0.369 HMGN1/ENSG00000205581.6 0.369 LYRM2/ENSG00000083099.6 0.368 S100PBP/ENSG00000116497.13 0.368 ZMYM5/ENSG00000132950.14 0.367 KLHL24/ENSG00000114796.10 0.367 DMXL2/ENSG00000104093.9 0.366 ZNF451/ENSG00000112200.12 0.365 RBBP5/ENSG00000117222.9 0.364 EVL/ENSG00000196405.8 0.364 RBM26/ENSG00000139746.11 0.362 SNX24/ENSG00000064652.6 0.362 NT5C2/ENSG00000076685.14 0.362 IGF2BP2/ENSG00000073792.11 0.362 VMP1/ENSG00000062716.5 0.362 AP001877.1/ENSG00000256885.1 0.359 LBR/ENSG00000143815.10 0.359 DYNC2H1/ENSG00000187240.9 0.359 YWHAQ/ENSG00000134308.9 0.358 RIOK3/ENSG00000101782.10 0.357 NGDN/ENSG00000129460.11 0.356 CEP350/ENSG00000135837.11 0.356 CLUAP1/ENSG00000103351.8 0.355 OS9/ENSG00000135506.11 0.353 ANKIB1/ENSG00000001629.5 0.353 GGPS1/ENSG00000152904.7 0.353 LRP6/ENSG00000070018.4 0.353 PLEKHA1/ENSG00000107679.10 0.352 TJP1/ENSG00000104067.12 0.352 CETN3/ENSG00000153140.4 0.351 L3MBTL3/ENSG00000198945.3 0.35 PRPF3/ENSG00000117360.8 0.35 STXBP4/ENSG00000166263.9 0.35 MSL1/ENSG00000188895.6 0.35 C1ORF27/ENSG00000157181.10 0.35 SCAPER/ENSG00000140386.8 0.349 RNF213/ENSG00000173821.15 0.349 STK36/ENSG00000163482.7 0.347 DCUN1D4/ENSG00000109184.10 0.347 DSC2/ENSG00000134755.10 0.347 SCYL2/ENSG00000136021.13 0.346 STRIP1/ENSG00000143093.9 0.345 TMTC3/ENSG00000139324.7 0.345 VEZF1/ENSG00000136451.4 0.344 CCNT2/ENSG00000082258.8 0.344 IFT43/ENSG00000119650.8 0.344 HSF2/ENSG00000025156.7 0.344 USF1/ENSG00000158773.10 0.343 DCTN5/ENSG00000166847.5 0.343 ZNF493/ENSG00000196268.7 0.343 SSR2/ENSG00000163479.9 0.342 PPP2R5E/ENSG00000154001.9 0.342 XRRA1/ENSG00000166435.11 0.341 FXYD6/ENSG00000137726.11 0.341 ELMSAN1/ENSG00000156030.8 0.341 VPS13B/ENSG00000132549.14 0.34 SELENBP1/ENSG00000143416.15 0.34 SORT1/ENSG00000134243.7 0.34 CDO1/ENSG00000129596.4 0.339 GSE1/ENSG00000131149.13 0.338 TOP2B/ENSG00000077097.9 0.338 YIPF1/ENSG00000058799.9 0.337 JUP/ENSG00000173801.12 0.336 KIF13B/ENSG00000197892.8 0.336 CLHC1/ENSG00000162994.11 0.336 BTRC/ENSG00000166167.13 0.336 YLPM1/ENSG00000119596.12 0.335 MSL3/ENSG00000005302.13 0.335 KIF3A/ENSG00000131437.11 0.335 ILF2/ENSG00000143621.12 0.335 CTNNA1/ENSG00000044115.15 0.334 CTNNBL1/ENSG00000132792.14 0.333 SLC39A10/ENSG00000196950.9 0.333 ZNF22/ENSG00000165512.4 0.333 OARD1/ENSG00000124596.12 0.332 KRBOX4/ENSG00000147121.11 0.332 LINC00665/ENSG00000232677.2 0.331 CWC27/ENSG00000153015.11 0.331 SPECC1L/ENSG00000100014.15 0.33 RP5-930J4.4/ENSG00000203394.2 0.33 ARMCX5/ENSG00000125962.9 0.329 LANCL1/ENSG00000115365.7 0.329 HDAC1/ENSG00000116478.7 0.329 PKN2/ENSG00000065243.14 0.328 LINC00657/ENSG00000260032.1 0.328 ZNF207/ENSG00000010244.12 0.327 CMTM6/ENSG00000091317.7 0.327 PRPSAP2/ENSG00000141127.10 0.327 HIPK2/ENSG00000064393.11 0.327 MED10/ENSG00000133398.3 0.327 TGOLN2/ENSG00000152291.9 0.327 LTN1/ENSG00000198862.8 0.326 VIPAS39/ENSG00000151445.11 0.326 TUBD1/ENSG00000108423.10 0.325 TBC1D24/ENSG00000162065.7 0.324 KLHL9/ENSG00000198642.5 0.324 TRAPPC11/ENSG00000168538.11 0.324 MORN2/ENSG00000188010.8 0.324 FER/ENSG00000151422.8 0.324 STAM2/ENSG00000115145.5 0.324 MED19/ENSG00000156603.10 0.323 RP11-690G19.3/ENSG00000266753.2 0.322 DDX52/ENSG00000141141.10 0.322 GTF2B/ENSG00000137947.7 0.321 CBWD2/ENSG00000136682.10 0.32 SMG1/ENSG00000157106.12 0.32 ASB8/ENSG00000177981.6 0.32 UHRF2/ENSG00000147854.12 0.32 INIP/ENSG00000148153.9 0.32 NCOR1/ENSG00000141027.16 0.32 MARK3/ENSG00000075413.13 0.319 PSMC6/ENSG00000100519.6 0.319 MAP9/ENSG00000164114.14 0.319 WDR33/ENSG00000136709.7 0.319 TMEM222/ENSG00000186501.9 0.318 NUMA1/ENSG00000137497.13 0.318 SETD5/ENSG00000168137.11 0.317 TMTC4/ENSG00000125247.11 0.317 DCTN1/ENSG00000204843.8 0.317 ZNF544/ENSG00000198131.9 0.317 FYN/ENSG00000010810.12 0.317 KIN/ENSG00000151657.6 0.315 ZNF429/ENSG00000197013.5 0.315 IK/ENSG00000113141.10 0.315 XRCC1/ENSG00000073050.7 0.315 SYAP1/ENSG00000169895.5 0.315 RRAGB/ENSG00000083750.8 0.314 COG5/ENSG00000164597.8 0.314 MLL/ENSG00000118058.16 0.313 RIT1/ENSG00000143622.5 0.313 DNALI1/ENSG00000163879.9 0.313 ESYT1/ENSG00000139641.8 0.313 CCT6P3/ENSG00000234585.2 0.312 SUPV3L1/ENSG00000156502.9 0.31 CTBP1/ENSG00000159692.11 0.31 ZNF655/ENSG00000197343.5 0.309 GHITM/ENSG00000165678.15 0.309 RERE/ENSG00000142599.13 0.308 ZC3H8/ENSG00000144161.7 0.308 CCDC174/ENSG00000154781.11 0.307 TNKS/ENSG00000173273.11 0.306 RNF216/ENSG00000011275.14 0.306 ZFP90/ENSG00000184939.10 0.306 TSEN2/ENSG00000154743.13 0.305 DOPEY1/ENSG00000083097.10 0.305 NKTR/ENSG00000114857.13 0.305 KIF21A/ENSG00000139116.13 0.304 ZNF627/ENSG00000198551.5 0.304 WBP1/ENSG00000239779.2 0.304 CRYBB2P1/ENSG00000100058.7 0.303 WDR26/ENSG00000162923.10 0.303 ZNF430/ENSG00000118620.8 0.302 FKBP7/ENSG00000079150.13 0.301 ABCC5/ENSG00000114770.12 0.301 TULP4/ENSG00000130338.8 0.3 GABARAPL2/ENSG00000034713.3 0.3 GPR22/ENSG00000172209.4 0.3 ARMC8/ENSG00000114098.13 0.3 ZDHHC2/ENSG00000104219.8 0.3 RP11-363E7.4/ENSG00000260912.1 0.3 LRCH3/ENSG00000186001.8 0.299 RNPC3/ENSG00000185946.11 0.298 MAP3K13/ENSG00000073803.9 0.298 TRAPPC1/ENSG00000170043.7 0.297 NECAP2/ENSG00000157191.15 0.297 CTSB/ENSG00000164733.16 0.296 RP11-974F13.6/ENSG00000250763.1 0.296 CRYZL1/ENSG00000205758.7 0.295 TOR1AIP2/ENSG00000169905.7 0.295 KIF9/ENSG00000088727.8 0.294 AC004057.1/ENSG00000196656.6 0.294 RCOR3/ENSG00000117625.9 0.293 RBP1/ENSG00000114115.5 0.293 PRRC2C/ENSG00000117523.11 0.292 FBXO7/ENSG00000100225.13 0.292 ZNF626/ENSG00000188171.10 0.292 PIN4/ENSG00000102309.8 0.291 KDM3A/ENSG00000115548.12 0.291 METTL14/ENSG00000145388.9 0.291 DCAF16/ENSG00000163257.6 0.291 DNAJC9/ENSG00000213551.4 0.291 BBS7/ENSG00000138686.5 0.291 MNAT1/ENSG00000020426.6 0.29 IPO9/ENSG00000198700.5 0.29 ZDHHC17/ENSG00000186908.10 0.289 NHSL1/ENSG00000135540.7 0.289 WNK1/ENSG00000060237.12 0.289 PHC3/ENSG00000173889.10 0.288 CTCF/ENSG00000102974.10 0.288 KIAA0430/ENSG00000166783.15 0.288 DPP10/ENSG00000175497.12 0.288 ICA1/ENSG00000003147.13 0.287 TMEM245/ENSG00000106771.8 0.287 PPP1R9A/ENSG00000158528.7 0.286 NEMF/ENSG00000165525.13 0.285 ANKRD36/ENSG00000135976.12 0.285 MAPRE2/ENSG00000166974.8 0.284 EIF4G2/ENSG00000110321.11 0.284 FAM117B/ENSG00000138439.10 0.283 ALG11/ENSG00000253710.1 0.283 KBTBD4/ENSG00000123444.9 0.283 FGFR1OP2/ENSG00000111790.9 0.283 RAB33B/ENSG00000172007.5 0.283 ST3GAL6/ENSG00000064225.8 0.281 MLLT3/ENSG00000171843.11 0.28 FIP1L1/ENSG00000145216.11 0.28 FOXA1/ENSG00000129514.4 0.28 IFT46/ENSG00000118096.3 0.279 SMU1/ENSG00000122692.7 0.278 RNF214/ENSG00000167257.6 0.277 KHDRBS1/ENSG00000121774.12 0.276 DLD/ENSG00000091140.8 0.276 CTC-429P9.3/ENSG00000269044.1 0.276 RALGAPA1/ENSG00000174373.11 0.276 UBE2R2/ENSG00000107341.4 0.276 C15ORF41/ENSG00000186073.7 0.275 DHX40/ENSG00000108406.5 0.275 WDR70/ENSG00000082068.4 0.275 DCUN1D1/ENSG00000043093.9 0.274 UBE2H/ENSG00000186591.7 0.274 RPF1/ENSG00000117133.6 0.274 SOS1/ENSG00000115904.8 0.274 DUSP11/ENSG00000144048.6 0.273 ANAPC7/ENSG00000196510.8 0.273 SPATS2/ENSG00000123352.13 0.273 NFE2L2/ENSG00000116044.11 0.273 FNIP1/ENSG00000217128.6 0.273 ATE1/ENSG00000107669.13 0.273 EIF4G3/ENSG00000075151.15 0.272 YME1L1/ENSG00000136758.14 0.272 BRCC3/ENSG00000185515.10 0.272 PATZ1/ENSG00000100105.13 0.272 DYNC1H1/ENSG00000197102.6 0.271 KANSL3/ENSG00000114982.13 0.271 TUBB4B/ENSG00000188229.5 0.269 FSD1L/ENSG00000106701.7 0.269 MUT/ENSG00000146085.7 0.269 SHPRH/ENSG00000146414.11 0.269 ALS2/ENSG00000003393.10 0.269 FKBP3/ENSG00000100442.6 0.269 TADA2A/ENSG00000108264.12 0.269 HERC2P9/ENSG00000206149.6 0.269 SEC24C/ENSG00000176986.10 0.268 UPF2/ENSG00000151461.15 0.268 ELL2/ENSG00000118985.10 0.268 RNF20/ENSG00000155827.7 0.267 N4BP2/ENSG00000078177.9 0.267 PHF10/ENSG00000130024.10 0.267 RAB14/ENSG00000119396.6 0.267 CHD7/ENSG00000171316.7 0.267 RP5-821D11.7/ENSG00000184068.2 0.266 WHSC1/ENSG00000109685.13 0.266 UBE4A/ENSG00000110344.5 0.266 SLC25A27/ENSG00000153291.11 0.266 SAR1B/ENSG00000152700.9 0.266 EPB41/ENSG00000159023.14 0.266 YTHDF3/ENSG00000185728.12 0.266 LYRM1/ENSG00000102897.5 0.266 C20ORF112/ENSG00000197183.8 0.265 DDX17/ENSG00000100201.14 0.264 CARD8/ENSG00000105483.12 0.264 RAB2B/ENSG00000129472.8 0.263 ZNF737/ENSG00000237440.4 0.263 N6AMT2/ENSG00000150456.6 0.263 THADA/ENSG00000115970.14 0.263 SIAH1/ENSG00000196470.7 0.261 CTB-25J19.9/ENSG00000269163.1 0.261 ADAM17/ENSG00000151694.8 0.261 TAF8/ENSG00000137413.11 0.261 TMEM237/ENSG00000155755.14 0.261 KIAA0100/ENSG00000007202.10 0.26 EBAG9/ENSG00000147654.10 0.26 RHOBTB3/ENSG00000164292.8 0.26 PHC2/ENSG00000134686.12 0.26 SPTAN1/ENSG00000197694.9 0.259 TVP23B/ENSG00000171928.9 0.259 NOL9/ENSG00000162408.10 0.259 TEAD1/ENSG00000187079.10 0.259 DUSP6/ENSG00000139318.7 0.259 KLHL28/ENSG00000179454.8 0.258 KDM4A/ENSG00000066135.8 0.257 NME7/ENSG00000143156.9 0.257 ALG14/ENSG00000172339.7 0.257 CEP164P1/ENSG00000226937.3 0.257 CBWD1/ENSG00000172785.14 0.256 PHACTR4/ENSG00000204138.8 0.256 TOP1/ENSG00000198900.5 0.255 SMC5/ENSG00000198887.7 0.254 CNTRL/ENSG00000119397.12 0.254 TRAPPC2/ENSG00000196459.9 0.253 RAB22A/ENSG00000124209.3 0.253 INO80D/ENSG00000114933.11 0.253 SEL1L/ENSG00000071537.9 0.253 RPGR/ENSG00000156313.8 0.253 TRPM7/ENSG00000092439.9 0.252 GPBP1L1/ENSG00000159592.6 0.252 SAMD8/ENSG00000156671.7 0.252 TMEM9/ENSG00000116857.11 0.251 HSPA13/ENSG00000155304.4 0.25 RAPGEF2/ENSG00000109756.4 0.25 MYEF2/ENSG00000104177.13 Overrepresented GO terms in EP #17: Term Pvalue RNA metabolic process 6.32E-25 gene expression 1.44E-20 nucleic acid-templated transcription 5.09E-20 heterocycle metabolic process 3.58E-17 cellular aromatic compound metabolic process 3.94E-17 organic cyclic compound metabolic process 2.01E-15 cellular nitrogen compound metabolic process 1.63E-14 nucleobase-containing compound biosynthetic process 1.76E-14 primary metabolic process 1.11E-13 macromolecule biosynthetic process 2.42E-13 regulation of macromolecule metabolic process 8.17E-11 regulation of nucleobase-containing compound metabolic process 1.59E-10 regulation of biosynthetic process 5.70E-09 cellular biosynthetic process 7.27E-09 protein modification by small protein conjugation or removal 7.33E-09 regulation of RNA biosynthetic process 1.37E-08 "regulation of transcription, DNA-templated " 1.87E-08 protein modification process 4.21E-08 negative regulation of biosynthetic process 1.68E-06 cellular protein metabolic process 2.95E-06 chromatin modification 5.89E-06 positive regulation of nucleobase-containing compound metabolic process 6.20E-06 macromolecular complex subunit organization 7.13E-06 "mRNA splicing, via spliceosome " 9.81E-06 cell cycle 1.04E-05 "RNA splicing, via transesterification reactions " 1.35E-05 positive regulation of macromolecule metabolic process 1.58E-05 protein acylation 2.04E-05 regulation of RNA splicing 2.07E-05 negative regulation of nucleobase-containing compound metabolic process 2.38E-05 positive regulation of RNA biosynthetic process 3.76E-05 regulation of transcription from RNA polymerase II promoter 4.26E-05 peptidyl-lysine acetylation 5.25E-05 modification-dependent macromolecule catabolic process 6.91E-05 negative regulation of RNA biosynthetic process 7.41E-05 chromatin remodeling 9.41E-05 "negative regulation of transcription, DNA-templated " 9.58E-05 peptidyl-amino acid modification 0.000136312 ubiquitin-dependent protein catabolic process 0.00016054 proteolysis involved in cellular protein catabolic process 0.000166225 cellular response to stress 0.000169899 "positive regulation of transcription, DNA-templated " 0.000214158 positive regulation of cellular process 0.000216545 regulation of mRNA processing 0.00027515 histone modification 0.000429675 protein polyubiquitination 0.000434527 protein alkylation 0.000487113 negative regulation of macromolecule metabolic process 0.00049043 mRNA export from nucleus 0.000685644 histone acetylation 0.000865002 RNA localization 0.000903045 cellular metabolic process 0.001067234 cellular component organization or biogenesis 0.0010999 microtubule-based process 0.001280694 cellular localization 0.001291071 positive regulation of biosynthetic process 0.001586306 mitotic cell cycle process 0.001589649 macromolecule metabolic process 0.00160554 RNA transport 0.001787456 "regulation of alternative mRNA splicing, via spliceosome " 0.002070872 internal protein amino acid acetylation 0.002428055 regulation of mitotic cell cycle 0.002431832 histone H4-K16 acetylation 0.002569754 protein ubiquitination 0.002650721 ribonucleoprotein complex export from nucleus 0.003316063 protein catabolic process 0.003730823 regulation of chromatin organization 0.003934117 mRNA processing 0.004172321 "regulation of gene expression, epigenetic " 0.005327887 peptidyl-lysine methylation 0.007274401 regulation of biological process 0.009296446 maintenance of chromatin silencing 0.01085692 intraciliary retrograde transport 0.012657844 posttranscriptional regulation of gene expression 0.014055769 histone H4-K5 acetylation 0.01494656 histone H4-K8 acetylation 0.01494656 regulation of histone methylation 0.017763897 cilium assembly 0.018411298 cell projection morphogenesis 0.018802047 positive regulation of cell death 0.018812439 gene silencing 0.019596446 nucleobase-containing compound transport 0.019819938 histone H3-K36 methylation 0.020384078 regulation of RNA export from nucleus 0.020384078 positive regulation of apoptotic process 0.02073097 cellular response to alcohol 0.021528103 regulation of mRNA stability 0.021926186 negative regulation of cellular process 0.025309247 macromolecule methylation 0.026075541 chromosome segregation 0.026270048 polynucleotide dephosphorylation 0.026277449 intraciliary transport 0.026604852 intra-Golgi vesicle-mediated transport 0.027670942 regulation of cell cycle process 0.027683584 ER-associated ubiquitin-dependent protein catabolic process 0.030051763 maintenance of mitotic sister chromatid cohesion 0.030952143 ER to Golgi vesicle-mediated transport 0.031431961 negative regulation of cell cycle 0.03373665 transcription from RNA polymerase II promoter 0.034234971 cellular component assembly 0.035198701 Golgi to endosome transport 0.035763148 regulation of cellular macromolecule biosynthetic process 0.036346922 negative regulation of translation 0.037294281 androgen receptor signaling pathway 0.038585383 regulation of hematopoietic progenitor cell differentiation 0.044865202 single-organism organelle organization 0.047739819 smoothened signaling pathway 0.049078286 --------------------------------------------- "EP #18: 37 cells, 170 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.1, St4_3_: 0.229885057471264, stage4: 0.0285714285714286, St5_3_: 0.0958904109589041, stage5_: 0.015625, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0, " Top Genes: 1.641 FLRT2/ENSG00000185070.6 1.601 C10ORF10/ENSG00000165507.8 1.493 NPY/ENSG00000122585.3 1.328 RFX6/ENSG00000185002.5 1.235 KRT19/ENSG00000171345.9 1.213 ACTC1/ENSG00000159251.6 1.178 SLITRK2/ENSG00000185985.7 1.108 CTB-118N6.3/ENSG00000248445.1 1.08 CELA3A/ENSG00000142789.15 1.073 TFPI2/ENSG00000105825.7 1.033 RP5-831C21.1/ENSG00000236168.1 1.011 LINC00340/ENSG00000238274.2 0.985 ASAH1/ENSG00000104763.13 0.926 USP18/ENSG00000184979.9 0.916 STARD4-AS1/ENSG00000246859.2 0.916 CHD7/ENSG00000171316.7 0.9 DOCK5/ENSG00000147459.13 0.893 RP11-1143G9.4/ENSG00000257764.2 0.891 MFAP4/ENSG00000166482.7 0.857 GADD45A/ENSG00000116717.7 0.854 CPE/ENSG00000109472.9 0.848 OPRK1/ENSG00000082556.6 0.834 BTG2/ENSG00000159388.5 0.834 GCNT1/ENSG00000187210.8 0.822 FAM13A/ENSG00000138640.10 0.818 DUSP10/ENSG00000143507.13 0.814 KRT15/ENSG00000171346.9 0.781 CACNA2D1/ENSG00000153956.11 0.776 EMP2/ENSG00000213853.5 0.771 PGA5/ENSG00000256713.3 0.748 ORMDL3/ENSG00000172057.5 0.747 MUC15/ENSG00000169550.8 0.738 CELA3B/ENSG00000219073.3 0.731 L1TD1/ENSG00000240563.1 0.717 FRA10AC1/ENSG00000148690.10 0.713 CALCOCO2/ENSG00000136436.9 0.712 CCDC150/ENSG00000144395.13 0.712 PTHLH/ENSG00000087494.11 0.701 GOLPH3L/ENSG00000143457.6 0.693 ZNF326/ENSG00000162664.11 0.692 RP11-438E5.1/ENSG00000249307.1 0.684 GRIA3/ENSG00000125675.13 0.678 NEDD1/ENSG00000139350.7 0.667 ZFAND4/ENSG00000172671.15 0.667 ZNF232/ENSG00000167840.9 0.665 OLFML2B/ENSG00000162745.6 0.663 NEUROG3/ENSG00000122859.4 0.663 KLK12/ENSG00000186474.11 0.653 UBXN11/ENSG00000158062.16 0.652 GSTA1/ENSG00000243955.1 0.648 COBLL1/ENSG00000082438.11 0.642 GPC3/ENSG00000147257.9 0.639 TGFB2/ENSG00000092969.7 0.634 RP11-6N17.10/ENSG00000264701.1 0.629 LPHN3/ENSG00000150471.10 0.625 FRYL/ENSG00000075539.9 0.609 ARPC5/ENSG00000162704.11 0.599 SEMA6A/ENSG00000092421.12 0.599 CBLB/ENSG00000114423.14 0.596 ENC1/ENSG00000171617.9 0.596 HIST1H2BD/ENSG00000158373.7 0.594 AMPD2/ENSG00000116337.11 0.592 BAZ2B/ENSG00000123636.13 0.565 SLC30A7/ENSG00000162695.7 0.561 SLC12A2/ENSG00000064651.9 0.542 FRZB/ENSG00000162998.4 0.54 SLC39A11/ENSG00000133195.7 0.526 CCDC12/ENSG00000160799.7 0.52 PTPRG/ENSG00000144724.14 0.517 UFM1/ENSG00000120686.7 0.511 CACUL1/ENSG00000151893.10 0.496 AHR/ENSG00000106546.8 0.493 RP11-631M6.3/ENSG00000251682.1 0.489 RP11-96L7.2/ENSG00000227269.1 0.481 RP11-497H16.8/ENSG00000253333.1 0.48 CALCOCO1/ENSG00000012822.11 0.471 TIMP3/ENSG00000100234.11 0.471 YARS2/ENSG00000139131.8 0.47 GSDMB/ENSG00000073605.14 0.46 S100A6/ENSG00000197956.5 0.454 RP11-343J3.2/ENSG00000236154.1 0.452 GNG11/ENSG00000127920.4 0.45 TBPL1/ENSG00000028839.4 0.45 SULF2/ENSG00000196562.10 0.444 SNHG1/ENSG00000255717.1 0.441 C8ORF56/ENSG00000236939.2 0.439 LYZ/ENSG00000090382.2 0.439 TMEM60/ENSG00000135211.5 0.437 RP11-344E13.3/ENSG00000233098.3 0.434 TRIO/ENSG00000038382.13 0.434 DAP3/ENSG00000132676.10 0.431 LPAR6/ENSG00000139679.11 0.423 CLPS/ENSG00000137392.5 0.418 PBXIP1/ENSG00000163346.12 0.415 GFRA1/ENSG00000151892.10 0.411 RP4-781K5.2/ENSG00000228830.1 0.411 TACC2/ENSG00000138162.13 0.411 DAB2/ENSG00000153071.10 0.405 PRICKLE2/ENSG00000163637.7 0.404 RABGAP1L/ENSG00000152061.17 0.402 NPTX1/ENSG00000171246.5 0.402 FAM64A/ENSG00000129195.10 0.397 FAM46C/ENSG00000183508.4 0.396 SLAIN1/ENSG00000139737.16 0.392 DSEL/ENSG00000171451.13 0.392 ZBTB48/ENSG00000204859.7 0.377 APOC3/ENSG00000110245.7 0.371 BAALC/ENSG00000164929.12 0.367 HSPA12A/ENSG00000165868.8 0.366 CEP63/ENSG00000182923.11 0.364 SFRP1/ENSG00000104332.7 0.364 CLPTM1L/ENSG00000049656.9 0.359 DLL1/ENSG00000198719.7 0.357 AKT1/ENSG00000142208.11 0.357 HTATSF1/ENSG00000102241.7 0.352 WIPI1/ENSG00000070540.8 0.351 RP11-318M2.3/ENSG00000253851.1 0.339 NET1/ENSG00000173848.14 0.335 PRPF38A/ENSG00000134748.11 0.332 MATN2/ENSG00000132561.9 0.331 EXOC7/ENSG00000182473.15 0.331 CWF19L1/ENSG00000095485.12 0.33 PHTF2/ENSG00000006576.12 0.328 CDCP1/ENSG00000163814.3 0.327 ICK/ENSG00000112144.11 0.325 STARD10/ENSG00000214530.2 0.32 UBA5/ENSG00000081307.8 0.317 SUSD2/ENSG00000099994.10 0.315 SPAG6/ENSG00000077327.11 0.314 AL358781.1/ENSG00000176868.1 0.313 RPS27L/ENSG00000185088.8 0.313 EPHA1/ENSG00000146904.4 0.31 IGF2R/ENSG00000197081.7 0.31 ELMO1/ENSG00000155849.11 0.306 ZSWIM6/ENSG00000130449.5 0.304 KIAA0355/ENSG00000166398.7 0.304 LDB1/ENSG00000198728.6 0.303 BET1/ENSG00000105829.6 0.302 RP11-129B9.1/ENSG00000237774.3 0.299 RP11-573N10.1/ENSG00000269189.1 0.291 XBP1/ENSG00000100219.12 0.29 EPHA4/ENSG00000116106.7 0.29 ROR1/ENSG00000185483.7 0.29 CCDC80/ENSG00000091986.11 0.289 SLC7A2/ENSG00000003989.12 0.289 RP11-73M18.9/ENSG00000269963.1 0.287 SLC38A5/ENSG00000017483.10 0.283 NIPAL3/ENSG00000001461.12 0.283 MEST/ENSG00000106484.9 0.283 PDK2/ENSG00000005882.6 0.28 UBQLN1/ENSG00000135018.9 0.277 CADM1/ENSG00000182985.11 0.277 PRDX1/ENSG00000117450.9 0.276 EIF1AY/ENSG00000198692.5 0.274 ATP6V1E1/ENSG00000131100.8 0.274 BRD7P3/ENSG00000169075.7 0.273 RGL1/ENSG00000143344.10 0.273 PTK2/ENSG00000169398.15 0.271 HEPH/ENSG00000089472.12 0.271 PTCD3/ENSG00000132300.14 0.269 ANKRD28/ENSG00000206560.6 0.268 TIMM50/ENSG00000105197.5 0.263 HIST2H2BE/ENSG00000184678.8 0.262 CTD-2583A14.8/ENSG00000269867.1 0.258 KIAA0247/ENSG00000100647.7 0.257 PSMB2/ENSG00000126067.7 0.257 VPS52/ENSG00000223501.4 0.257 IQCK/ENSG00000174628.12 0.255 SDAD1/ENSG00000198301.7 0.254 NEUROD1/ENSG00000162992.3 Overrepresented GO terms in EP #18: Term Pvalue endocrine pancreas development 0.001895179 response to insulin-like growth factor stimulus 0.002954561 positive regulation of non-canonical Wnt signaling pathway 0.005483692 "regulation of Wnt signaling pathway, planar cell polarity pathway " 0.005483692 neuron projection development 0.007118276 regulation of organ morphogenesis 0.008547228 positive regulation of cell-substrate adhesion 0.008633077 regulation of stress-activated MAPK cascade 0.011966357 neurogenesis 0.012226685 regulation of cell development 0.013441085 cell adhesion involved in heart morphogenesis 0.017516305 signal transduction 0.017893071 neuron differentiation 0.018472198 signaling 0.019707544 establishment of planar polarity 0.022767638 tissue morphogenesis 0.028323937 cell migration 0.028691434 glial cell-derived neurotrophic factor receptor signaling pathway 0.029019716 protein K69-linked ufmylation 0.029019716 regulation of nervous system development 0.029651134 cell death 0.034540237 epithelium development 0.034645339 regulation of cell-matrix adhesion 0.042265137 protein ufmylation 0.043270126 innervation 0.046578928 regulation of neuron migration 0.046578928 transmembrane receptor protein tyrosine kinase signaling pathway 0.047315162 central nervous system development 0.047931638 positive regulation of fat cell differentiation 0.048810542 --------------------------------------------- "EP #19: 351 cells, 231 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0158730158730159, stage2_: 0.705882352941177, stage3_: 0.957142857142857, St4_3_: 0.770114942528736, stage4: 0.585714285714286, St5_3_: 0.808219178082192, stage5_: 0.34375, stage6.2_: 0.292682926829268, stage6.7_: 0.197368421052632, stage6.14_: 0.104477611940299, " Top Genes: 2.034 CDH6/ENSG00000113361.8 1.826 MEIS1/ENSG00000143995.14 1.742 IFITM3/ENSG00000142089.11 1.538 FABP5/ENSG00000164687.6 1.521 GPC3/ENSG00000147257.9 1.504 FN1/ENSG00000115414.14 1.493 DHRS3/ENSG00000162496.4 1.401 VCAN/ENSG00000038427.11 1.382 LRRC16A/ENSG00000079691.15 1.336 CYB5A/ENSG00000166347.13 1.303 AC107016.1/ENSG00000225410.1 1.27 RBP1/ENSG00000114115.5 1.174 FZD5/ENSG00000163251.3 1.149 ZFP36L2/ENSG00000152518.5 1.128 AC132217.4/ENSG00000240801.1 1.101 CDH1/ENSG00000039068.13 1.083 MECOM/ENSG00000085276.13 1.073 KRT8/ENSG00000170421.7 1.052 KRT18/ENSG00000111057.6 1.049 ID2/ENSG00000115738.5 1.019 PDGFA/ENSG00000197461.9 1.008 ARRDC3/ENSG00000113369.4 1 ANXA2/ENSG00000182718.11 0.986 S100A10/ENSG00000197747.4 0.952 MEIS2/ENSG00000134138.14 0.941 TSPAN6/ENSG00000000003.10 0.929 WEE1/ENSG00000166483.6 0.91 AXL/ENSG00000167601.7 0.882 CCND2/ENSG00000118971.3 0.88 SOX11/ENSG00000176887.5 0.874 BMPR1B/ENSG00000138696.6 0.865 SCARNA22/ENSG00000249784.1 0.862 TES/ENSG00000135269.13 0.858 CD59/ENSG00000085063.10 0.85 HOXA3/ENSG00000105997.17 0.847 SEMA3C/ENSG00000075223.9 0.833 ZFP36L1/ENSG00000185650.8 0.792 ABRACL/ENSG00000146386.7 0.792 MAATS1/ENSG00000183833.12 0.776 CTSB/ENSG00000164733.16 0.772 RQCD1/ENSG00000144580.9 0.752 LYPD6B/ENSG00000150556.12 0.745 NPC2/ENSG00000119655.4 0.74 KIAA1217/ENSG00000120549.11 0.728 CAST/ENSG00000153113.18 0.717 DPYSL2/ENSG00000092964.11 0.714 PLEKHA5/ENSG00000052126.10 0.713 FNDC3B/ENSG00000075420.8 0.694 SMC3/ENSG00000108055.9 0.684 TRA2A/ENSG00000164548.6 0.677 ANXA3/ENSG00000138772.8 0.676 C1ORF56/ENSG00000143443.9 0.673 PBX1/ENSG00000185630.13 0.665 C3ORF58/ENSG00000181744.4 0.647 ASAH1/ENSG00000104763.13 0.647 KRT19/ENSG00000171345.9 0.646 RND3/ENSG00000115963.9 0.629 APPL2/ENSG00000136044.7 0.624 TTC39C/ENSG00000168234.8 0.623 SCUBE3/ENSG00000146197.7 0.619 CD47/ENSG00000196776.10 0.615 APOA1/ENSG00000118137.5 0.609 SSBP2/ENSG00000145687.11 0.605 EXPH5/ENSG00000110723.7 0.602 S100A11/ENSG00000163191.5 0.601 PDLIM1/ENSG00000107438.4 0.599 CADM1/ENSG00000182985.11 0.597 PTPRS/ENSG00000105426.10 0.584 KIAA1551/ENSG00000174718.7 0.578 TECR/ENSG00000099797.7 0.576 WFDC2/ENSG00000101443.13 0.574 RPN2/ENSG00000118705.12 0.572 PLD1/ENSG00000075651.11 0.572 CRABP2/ENSG00000143320.4 0.569 VCAN-AS1/ENSG00000249835.2 0.569 CLU/ENSG00000120885.15 0.566 PPP3CA/ENSG00000138814.12 0.564 RP11-344E13.3/ENSG00000233098.3 0.562 REEP3/ENSG00000165476.8 0.557 CA2/ENSG00000104267.5 0.544 HNF1A-AS1/ENSG00000241388.2 0.543 B2M/ENSG00000166710.12 0.543 LAPTM4A/ENSG00000068697.6 0.534 GCA/ENSG00000115271.6 0.532 PLD3/ENSG00000105223.14 0.525 GPX8/ENSG00000164294.9 0.525 BEX5/ENSG00000184515.6 0.515 HES1/ENSG00000114315.3 0.514 ANP32E/ENSG00000143401.10 0.511 RIMKLB/ENSG00000166532.11 0.508 ARGLU1/ENSG00000134884.9 0.507 SDC4/ENSG00000124145.5 0.5 SH3BGRL/ENSG00000131171.8 0.497 SNAPIN/ENSG00000143553.6 0.497 ODC1/ENSG00000115758.8 0.494 FOXP1/ENSG00000114861.14 0.493 ING3/ENSG00000071243.11 0.492 DCLRE1C/ENSG00000152457.13 0.492 BARD1/ENSG00000138376.6 0.484 REC8/ENSG00000100918.8 0.48 PDCD4/ENSG00000150593.11 0.476 FXYD6/ENSG00000137726.11 0.476 B4GALT1/ENSG00000086062.8 0.473 UCP2/ENSG00000175567.3 0.471 RBBP8/ENSG00000101773.12 0.469 SYNE2/ENSG00000054654.11 0.466 FKBP9/ENSG00000122642.6 0.465 PIP4K2A/ENSG00000150867.9 0.464 GOLIM4/ENSG00000173905.4 0.46 RARB/ENSG00000077092.14 0.459 SPRY2/ENSG00000136158.6 0.458 SRPRB/ENSG00000144867.6 0.458 GGCT/ENSG00000006625.13 0.457 CDC42/ENSG00000070831.11 0.456 IFITM2/ENSG00000185201.12 0.456 PCM1/ENSG00000078674.13 0.455 C11ORF49/ENSG00000149179.8 0.438 RP11-206L10.5/ENSG00000240618.1 0.437 ZC3HAV1/ENSG00000105939.8 0.435 IFT57/ENSG00000114446.4 0.433 FAM111A/ENSG00000166801.11 0.431 ANKRD36B/ENSG00000196912.8 0.43 TMEM106C/ENSG00000134291.7 0.428 SPINT2/ENSG00000167642.8 0.424 CETN2/ENSG00000147400.8 0.424 SERPING1/ENSG00000149131.11 0.421 MAT2B/ENSG00000038274.11 0.417 CHMP3/ENSG00000115561.10 0.416 DDAH1/ENSG00000153904.14 0.414 GNG5/ENSG00000174021.6 0.411 MSH6/ENSG00000116062.8 0.41 RP11-96D1.11/ENSG00000262160.1 0.409 CD164/ENSG00000135535.10 0.409 GALNT7/ENSG00000109586.7 0.408 CAMTA1/ENSG00000171735.14 0.407 PHGDH/ENSG00000092621.7 0.405 PROM1/ENSG00000007062.7 0.405 FAT1/ENSG00000083857.9 0.4 IQGAP1/ENSG00000140575.8 0.399 BEX2/ENSG00000133134.7 0.399 SPARC/ENSG00000113140.6 0.389 RAB25/ENSG00000132698.9 0.389 CDH2/ENSG00000170558.4 0.388 GLB1/ENSG00000170266.11 0.388 STON2/ENSG00000140022.5 0.386 CLDN6/ENSG00000184697.6 0.385 INSR/ENSG00000171105.9 0.384 PER2/ENSG00000132326.7 0.381 ZNF518B/ENSG00000178163.3 0.377 DENND2C/ENSG00000175984.10 0.376 GLYATL1P2/ENSG00000254717.2 0.372 RIN2/ENSG00000132669.8 0.368 ANK3/ENSG00000151150.15 0.364 CLNS1A/ENSG00000074201.3 0.364 RP11-139K1.2/ENSG00000227560.1 0.361 IDH1/ENSG00000138413.9 0.36 RP11-611O2.3/ENSG00000256664.1 0.36 LBR/ENSG00000143815.10 0.359 CCNYL1/ENSG00000163249.5 0.358 SNHG1/ENSG00000255717.1 0.347 PHACTR2/ENSG00000112419.10 0.346 BIRC2/ENSG00000110330.4 0.346 PLSCR1/ENSG00000188313.8 0.346 REST/ENSG00000084093.11 0.345 AMOT/ENSG00000126016.9 0.343 CDK4/ENSG00000135446.12 0.341 SLC12A2/ENSG00000064651.9 0.341 THAP9-AS1/ENSG00000251022.1 0.337 C12ORF75/ENSG00000235162.4 0.336 PSAT1/ENSG00000135069.9 0.335 RAB3B/ENSG00000169213.6 0.331 CTC-340A15.2/ENSG00000241956.5 0.323 CTNND1/ENSG00000198561.8 0.323 ZNF141/ENSG00000131127.9 0.322 ITGAV/ENSG00000138448.7 0.322 TMEM87A/ENSG00000103978.11 0.32 LINC00340/ENSG00000238274.2 0.319 NIT2/ENSG00000114021.6 0.318 C2CD5/ENSG00000111731.8 0.315 MGST1/ENSG00000008394.7 0.313 PAM/ENSG00000145730.16 0.309 ZNF75A/ENSG00000162086.10 0.308 NRP1/ENSG00000099250.12 0.308 TCTEX1D2/ENSG00000213123.5 0.307 MOV10/ENSG00000155363.14 0.305 AC106827.1/ENSG00000203647.1 0.304 C9ORF116/ENSG00000160345.8 0.301 CDCA7L/ENSG00000164649.15 0.3 HMGA1/ENSG00000137309.15 0.3 RP11-509E16.1/ENSG00000261452.1 0.3 LRPAP1/ENSG00000163956.6 0.299 SKA2/ENSG00000182628.8 0.296 HNRNPK/ENSG00000165119.14 0.295 PDGFC/ENSG00000145431.6 0.295 FGD5-AS1/ENSG00000225733.1 0.295 EPHA4/ENSG00000116106.7 0.294 EPB41L4A/ENSG00000129595.8 0.294 PLOD2/ENSG00000152952.7 0.293 EID1/ENSG00000255302.3 0.293 SUCLG2/ENSG00000172340.10 0.293 ATF7IP2/ENSG00000166669.9 0.292 C1ORF198/ENSG00000119280.12 0.29 TTC6/ENSG00000139865.12 0.289 GPC6/ENSG00000183098.6 0.287 CST3/ENSG00000101439.4 0.283 EFNA1/ENSG00000169242.7 0.282 MTTP/ENSG00000138823.8 0.281 TCF7L1/ENSG00000152284.4 0.28 PCNA/ENSG00000132646.6 0.28 PCYOX1/ENSG00000116005.7 0.276 NOP58/ENSG00000055044.6 0.274 CDK14/ENSG00000058091.12 0.274 SLC39A10/ENSG00000196950.9 0.273 CEP41/ENSG00000106477.13 0.269 ONECUT2/ENSG00000119547.4 0.268 UGGT2/ENSG00000102595.14 0.267 DNAJC16/ENSG00000116138.8 0.262 RP11-384F7.2/ENSG00000239268.2 0.26 MDK/ENSG00000110492.11 0.26 IMMP1L/ENSG00000148950.5 0.259 FUT10/ENSG00000172728.11 0.259 MFAP2/ENSG00000117122.9 0.256 DDX50/ENSG00000107625.8 0.256 HNRNPA0/ENSG00000177733.4 0.256 UXS1/ENSG00000115652.10 0.254 RP11-611O2.5/ENSG00000257181.1 0.254 PRTG/ENSG00000166450.7 0.253 EFEMP1/ENSG00000115380.14 0.252 SPG20/ENSG00000133104.8 0.252 RP11-469M7.1/ENSG00000260006.1 0.251 DCX/ENSG00000077279.12 Overrepresented GO terms in EP #19: Term Pvalue biological adhesion 2.58E-06 regulation of multicellular organismal development 7.34E-06 developmental process 1.36E-05 negative regulation of nervous system development 2.84E-05 regulation of cell differentiation 4.03E-05 negative regulation of cell development 5.99E-05 response to wounding 0.0002038 embryonic morphogenesis 0.00020751 negative regulation of biological process 0.000216895 renal system development 0.000249172 single-multicellular organism process 0.000378269 embryonic organ development 0.000416031 immune system development 0.000532977 adherens junction organization 0.000759493 hemopoiesis 0.000896807 signaling 0.000897699 blood vessel development 0.000906517 regulation of neurogenesis 0.001112779 cell morphogenesis involved in differentiation 0.001213808 negative regulation of viral process 0.001218895 reproductive system development 0.001350282 regulation of localization 0.001449287 exocrine system development 0.001633588 embryonic eye morphogenesis 0.00167877 signal transduction 0.001691595 cardiovascular system development 0.001852983 positive regulation of DNA replication 0.002048048 regulation of vesicle-mediated transport 0.002212911 cellular component morphogenesis 0.002356028 cell junction organization 0.002521422 positive regulation of cell migration 0.002747283 gland development 0.00290544 retinoid metabolic process 0.003229134 regulation of binding 0.00325429 neuronal stem cell population maintenance 0.00338162 multi-organism cellular process 0.003683959 regulation of anatomical structure morphogenesis 0.004179547 adrenal gland development 0.004183987 positive regulation of transport 0.004242886 response to external biotic stimulus 0.004574086 tube development 0.004931899 positive regulation of cellular component movement 0.005158262 positive regulation of locomotion 0.005308822 interspecies interaction between organisms 0.005353533 positive regulation of cell proliferation 0.00545751 angiogenesis 0.005621452 negative regulation of neuron projection development 0.006025353 programmed cell death 0.006097636 appendage development 0.006243806 response to inorganic substance 0.006265992 cellular component organization or biogenesis 0.006718536 tissue development 0.00698554 central nervous system development 0.007164726 immune effector process 0.007182806 response to virus 0.007702525 response to organic substance 0.007871045 cell-cell adhesion 0.008638229 regulation of cell size 0.009172376 response to glucocorticoid 0.009942173 kidney epithelium development 0.009942173 biological regulation 0.010247955 terpenoid metabolic process 0.010662581 animal organ regeneration 0.010858485 positive regulation of multicellular organismal process 0.010866259 negative regulation of viral genome replication 0.011556661 single organism cell adhesion 0.011800435 cell differentiation involved in embryonic placenta development 0.012142485 membrane assembly 0.012142485 response to endogenous stimulus 0.012422267 limb morphogenesis 0.012891299 placenta development 0.014254505 animal organ morphogenesis 0.014285508 platelet degranulation 0.014457534 morphogenesis of a branching epithelium 0.014982516 negative regulation of stem cell differentiation 0.015949436 positive regulation of fibroblast proliferation 0.017125021 epithelial tube morphogenesis 0.017829294 bone cell development 0.01870929 peptidyl-amino acid modification 0.019589605 single organismal cell-cell adhesion 0.019823966 heart morphogenesis 0.019965892 reproductive process 0.020612898 tissue morphogenesis 0.021007354 response to stimulus 0.021591926 extracellular matrix organization 0.021964325 skeletal system development 0.022223759 cell division 0.022433696 regulation of cell cycle 0.022586653 response to steroid hormone 0.023481601 negative regulation of cell proliferation 0.023689167 "regulation of symbiosis, encompassing mutualism through parasitism " 0.024172185 positive regulation of substrate adhesion-dependent cell spreading 0.024285748 epithelial cell development 0.025453473 negative regulation of cell death 0.025819413 low-density lipoprotein receptor particle metabolic process 0.025885085 eye development 0.026877399 mitotic cell cycle phase transition 0.028022415 neural tube development 0.028665586 cell activation 0.029997931 glycosaminoglycan catabolic process 0.031437506 negative regulation of neuron differentiation 0.031589155 cell motility 0.031590614 post-embryonic animal organ development 0.032046179 regulation of apoptotic process 0.032235658 positive regulation of developmental process 0.0344221 regulation of axonogenesis 0.035483247 L-serine biosynthetic process 0.036061743 negative regulation of cellular component organization 0.037986502 exocytosis 0.038315654 establishment or maintenance of cell polarity 0.038549437 circulatory system development 0.038700245 salivary gland morphogenesis 0.038800906 response to cadmium ion 0.038800906 regulation of cell motility 0.041484954 regulation of cell projection organization 0.041780842 cardiac septum morphogenesis 0.042827616 blood vessel remodeling 0.043209434 lymphocyte activation 0.044386699 regulation of receptor binding 0.0469802 telencephalon development 0.049134721 positive regulation of cell adhesion 0.04994918 --------------------------------------------- "EP #20: 713 cells, 328 genes" "Fraction of cells from each time pt- hesc_: 0.169811320754717, stage1_: 0.968253968253968, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 1, St5_3_: 1, stage5_: 0.953125, stage6.2_: 0.98780487804878, stage6.7_: 0.960526315789474, stage6.14_: 0.895522388059702, " Top Genes: 1.315 HIF1A/ENSG00000100644.12 1.296 NEDD4/ENSG00000069869.11 1.28 RGPD5/ENSG00000015568.8 1.228 AC144530.1/ENSG00000234742.1 1.159 SFPQ/ENSG00000116560.6 1.154 RP11-946L20.4/ENSG00000253103.1 1.112 GUSBP3/ENSG00000253203.2 1.075 RP3-368A4.5/ENSG00000271430.1 1.054 RP11-259O2.3/ENSG00000249731.1 1.043 RP11-129M6.1/ENSG00000251363.2 1.03 GPBP1/ENSG00000062194.11 1.027 LINC00504/ENSG00000248360.2 1.005 PTK2/ENSG00000169398.15 0.998 ANKRD10/ENSG00000088448.10 0.984 TOB1/ENSG00000141232.4 0.974 BLOC1S6/ENSG00000104164.6 0.966 RP11-703G6.1/ENSG00000249614.1 0.961 RP4-798C17.6/ENSG00000244479.2 0.924 PRR4/ENSG00000111215.6 0.923 PCM1/ENSG00000078674.13 0.917 MACF1/ENSG00000127603.19 0.901 TTTY15/ENSG00000233864.3 0.891 ABCD4/ENSG00000119688.16 0.891 RP11-573N10.1/ENSG00000269189.1 0.891 CERS5/ENSG00000139624.8 0.887 CHD7/ENSG00000171316.7 0.873 PRPF39/ENSG00000185246.13 0.871 AC004257.3/ENSG00000270143.1 0.871 RP11-346D14.1/ENSG00000259380.1 0.87 DST/ENSG00000151914.13 0.862 LUC7L/ENSG00000007392.12 0.83 REV3L/ENSG00000009413.11 0.817 NUTM2A-AS1/ENSG00000223482.3 0.813 ARID4B/ENSG00000054267.16 0.803 FUBP1/ENSG00000162613.12 0.802 USP34/ENSG00000115464.10 0.796 SEC31A/ENSG00000138674.12 0.792 CNOT2/ENSG00000111596.7 0.788 CBWD5/ENSG00000147996.12 0.779 RP11-349A22.5/ENSG00000257621.3 0.777 MTF2/ENSG00000143033.13 0.776 YIPF3/ENSG00000137207.7 0.776 KIAA1328/ENSG00000150477.10 0.771 RP11-206L10.5/ENSG00000240618.1 0.769 RP11-379K17.12/ENSG00000268220.1 0.761 RP11-234A1.1/ENSG00000242299.1 0.736 FSIP2/ENSG00000188738.9 0.735 JPX/ENSG00000225470.2 0.728 TCERG1/ENSG00000113649.7 0.727 CCNL2/ENSG00000221978.7 0.723 GLG1/ENSG00000090863.7 0.72 DNAJC16/ENSG00000116138.8 0.715 CHD2/ENSG00000173575.13 0.697 COPA/ENSG00000122218.10 0.693 MGEA5/ENSG00000198408.9 0.675 61E3.4/ENSG00000185864.12 0.665 SETD5-AS1/ENSG00000206573.4 0.663 NKTR/ENSG00000114857.13 0.663 UQCRC2/ENSG00000140740.6 0.663 RBM5/ENSG00000003756.12 0.654 VPS28/ENSG00000160948.9 0.644 JMJD1C/ENSG00000171988.13 0.641 DMTF1/ENSG00000135164.14 0.639 ZCCHC11/ENSG00000134744.9 0.638 RNF10/ENSG00000022840.11 0.636 FAM214A/ENSG00000047346.8 0.634 ELP2/ENSG00000134759.9 0.632 GIGYF2/ENSG00000204120.10 0.628 RP11-123C21.2/ENSG00000270986.1 0.628 AF131215.4/ENSG00000254556.1 0.622 RBM4B/ENSG00000173914.6 0.614 MED31/ENSG00000108590.6 0.608 TTC19/ENSG00000011295.10 0.602 ZNF638/ENSG00000075292.13 0.596 DDX42/ENSG00000198231.7 0.596 TOX4/ENSG00000092203.8 0.596 ATXN2/ENSG00000204842.9 0.585 AC159540.1/ENSG00000230606.5 0.585 AFF4/ENSG00000072364.8 0.579 ZNF207/ENSG00000010244.12 0.565 BRD8/ENSG00000112983.13 0.563 XRN1/ENSG00000114127.6 0.559 HERPUD1/ENSG00000051108.10 0.555 WSB1/ENSG00000109046.10 0.554 ZNF814/ENSG00000204514.5 0.554 RP11-5A11.1/ENSG00000255105.1 0.553 ITPA/ENSG00000125877.7 0.55 RANBP2/ENSG00000153201.11 0.547 SYNC/ENSG00000162520.10 0.547 PRPF38B/ENSG00000134186.7 0.545 CTD-2301A4.3/ENSG00000240729.1 0.539 ATP2B1/ENSG00000070961.10 0.532 EIF1AD/ENSG00000175376.4 0.531 POLR3E/ENSG00000058600.11 0.531 SNX14/ENSG00000135317.8 0.529 EXOC4/ENSG00000131558.10 0.529 UBAP2L/ENSG00000143569.14 0.525 WDR59/ENSG00000103091.10 0.524 PPFIA1/ENSG00000131626.11 0.523 DLG1/ENSG00000075711.15 0.522 ANKHD1/ENSG00000131503.16 0.519 WDR11/ENSG00000120008.11 0.516 MKRN1/ENSG00000133606.6 0.516 RP11-848P1.4/ENSG00000266340.1 0.511 POLR2J3/ENSG00000168255.13 0.507 CNOT1/ENSG00000125107.12 0.507 WTAP/ENSG00000146457.10 0.499 CELF1/ENSG00000149187.13 0.498 UBE2W/ENSG00000104343.15 0.497 SRSF2/ENSG00000161547.10 0.497 TMEM45A/ENSG00000181458.6 0.496 RP11-214K3.19/ENSG00000270061.1 0.496 FBXO38/ENSG00000145868.12 0.494 IFRD1/ENSG00000006652.9 0.49 ZC3H7A/ENSG00000122299.7 0.488 IFT20/ENSG00000109083.9 0.488 UGDH-AS1/ENSG00000249348.1 0.487 ARGLU1/ENSG00000134884.9 0.485 USP4/ENSG00000114316.8 0.485 TAF15/ENSG00000172660.7 0.484 SEC63/ENSG00000025796.9 0.484 PMPCB/ENSG00000105819.9 0.483 USP15/ENSG00000135655.9 0.482 DNAJC7/ENSG00000168259.9 0.477 SMIM15/ENSG00000188725.3 0.475 RP11-473M20.14/ENSG00000263072.1 0.473 PRPF40A/ENSG00000196504.11 0.472 RAF1/ENSG00000132155.7 0.472 FMNL2/ENSG00000157827.15 0.472 RP11-16E23.4/ENSG00000259924.1 0.471 C9ORF38/ENSG00000215066.3 0.47 RP11-1023L17.1/ENSG00000215158.5 0.47 VPS13A/ENSG00000197969.7 0.468 OXR1/ENSG00000164830.13 0.468 NUPL1/ENSG00000139496.11 0.467 RBM6/ENSG00000004534.10 0.463 TASP1/ENSG00000089123.11 0.462 CASC3/ENSG00000108349.10 0.462 RP11-72I8.1/ENSG00000260735.1 0.461 CCNT1/ENSG00000129315.5 0.461 RP11-46C20.1/ENSG00000250337.1 0.457 MUM1/ENSG00000160953.10 0.456 PUM2/ENSG00000055917.11 0.454 TTC17/ENSG00000052841.10 0.453 ATP9B/ENSG00000166377.15 0.452 GON4L/ENSG00000116580.13 0.452 NINL/ENSG00000101004.10 0.448 AEBP2/ENSG00000139154.10 0.444 RP11-33B1.1/ENSG00000245958.2 0.443 YAF2/ENSG00000015153.10 0.443 RP11-658F2.8/ENSG00000258297.1 0.443 MTG1/ENSG00000148824.13 0.44 KDM5A/ENSG00000073614.7 0.436 RP11-268I9.1/ENSG00000243303.1 0.435 TMX3/ENSG00000166479.5 0.435 FBXW4/ENSG00000107829.9 0.433 ORC4/ENSG00000115947.8 0.432 DCLRE1C/ENSG00000152457.13 0.428 PHKB/ENSG00000102893.11 0.426 TM9SF2/ENSG00000125304.8 0.423 FBXW7/ENSG00000109670.9 0.42 ITCH/ENSG00000078747.8 0.42 ANAPC5/ENSG00000089053.8 0.418 HM13/ENSG00000101294.12 0.416 SAT2/ENSG00000141504.7 0.415 METTL3/ENSG00000165819.7 0.414 CSNK2A1/ENSG00000101266.11 0.412 RP11-274B21.10/ENSG00000271553.1 0.412 ZNF431/ENSG00000196705.4 0.409 TAF2/ENSG00000064313.7 0.407 TRIM27/ENSG00000204713.6 0.406 AGK/ENSG00000006530.11 0.406 PDXDC1/ENSG00000179889.14 0.402 HEXA/ENSG00000213614.5 0.402 PPAPDC1B/ENSG00000147535.12 0.401 CCT7/ENSG00000135624.11 0.397 IGF1R/ENSG00000140443.9 0.397 HERC4/ENSG00000148634.10 0.396 GGNBP2/ENSG00000005955.8 0.395 TMEM182/ENSG00000170417.10 0.393 SEC23A/ENSG00000100934.10 0.392 C5ORF42/ENSG00000197603.9 0.39 INADL/ENSG00000132849.14 0.39 NCSTN/ENSG00000162736.11 0.389 ATF6B/ENSG00000213676.6 0.384 AL645728.2/ENSG00000215791.2 0.379 SNHG14/ENSG00000224078.6 0.378 METTL22/ENSG00000067365.10 0.377 AC011933.1/ENSG00000257073.1 0.37 AC007743.1/ENSG00000233251.3 0.37 C5ORF45/ENSG00000161010.10 0.369 RP3-449O17.1/ENSG00000244627.1 0.367 USP22/ENSG00000124422.7 0.367 TCF25/ENSG00000141002.13 0.364 GPATCH8/ENSG00000186566.7 0.364 RP1-179N16.3/ENSG00000237719.1 0.363 RP11-110G21.2/ENSG00000253475.1 0.362 DENND5A/ENSG00000184014.3 0.361 RP11-452L6.1/ENSG00000261474.1 0.358 MARCH6/ENSG00000145495.9 0.358 SMEK1/ENSG00000100796.13 0.356 RP11-106J23.2/ENSG00000255185.1 0.355 RIC3/ENSG00000166405.10 0.352 NT5C3A/ENSG00000122643.13 0.351 AC068831.15/ENSG00000259661.1 0.351 DDHD1/ENSG00000100523.10 0.349 NUMB/ENSG00000133961.15 0.349 CASC4/ENSG00000166734.14 0.348 GPS2/ENSG00000132522.11 0.347 MSI2/ENSG00000153944.6 0.346 AC040977.1/ENSG00000269871.1 0.345 AC069513.3/ENSG00000242086.3 0.345 GUSBP1/ENSG00000183666.11 0.343 UTY/ENSG00000183878.11 0.34 ZDHHC13/ENSG00000177054.9 0.339 STAG3L3/ENSG00000174353.12 0.338 MGA/ENSG00000174197.12 0.337 SMC1A/ENSG00000072501.12 0.336 MKLN1/ENSG00000128585.13 0.335 CPNE1/ENSG00000214078.7 0.335 DDX6/ENSG00000110367.6 0.334 STARD4-AS1/ENSG00000246859.2 0.334 FTX/ENSG00000230590.3 0.333 BDP1/ENSG00000145734.14 0.331 AC069277.2/ENSG00000189229.10 0.328 IARS/ENSG00000196305.13 0.328 ELF2/ENSG00000109381.15 0.326 RP11-894P9.1/ENSG00000246451.2 0.326 LYPLA2/ENSG00000011009.6 0.325 WDR73/ENSG00000177082.8 0.324 SPG7/ENSG00000197912.9 0.324 TRIP12/ENSG00000153827.9 0.322 AKAP13/ENSG00000170776.15 0.321 ANKRD26/ENSG00000107890.12 0.32 HOOK2/ENSG00000095066.7 0.32 RP11-73M18.10/ENSG00000269910.1 0.32 CLDND1/ENSG00000080822.12 0.319 ZNF587/ENSG00000198466.8 0.318 AC009948.5/ENSG00000223960.2 0.318 RP4-742J24.2/ENSG00000236526.1 0.317 KLHDC2/ENSG00000165516.6 0.316 CTC-273B12.8/ENSG00000269751.1 0.315 ZNF75A/ENSG00000162086.10 0.315 CACNB2/ENSG00000165995.14 0.315 BAZ2B/ENSG00000123636.13 0.314 EML4/ENSG00000143924.14 0.314 WDFY3/ENSG00000163625.11 0.313 HMBOX1/ENSG00000147421.12 0.311 TMEM50B/ENSG00000142188.12 0.311 LRPPRC/ENSG00000138095.14 0.311 NDUFV1/ENSG00000167792.7 0.31 CIRBP/ENSG00000099622.9 0.309 GOLGA8B/ENSG00000215252.7 0.309 MTFR1L/ENSG00000117640.13 0.307 RP11-264L1.4/ENSG00000260733.1 0.307 TMCC1/ENSG00000172765.12 0.306 AKAP8L/ENSG00000011243.12 0.304 AC004166.7/ENSG00000160828.13 0.303 CREB1/ENSG00000118260.9 0.303 CTD-2349P21.10/ENSG00000265791.1 0.299 MOB1B/ENSG00000173542.4 0.298 ZCCHC6/ENSG00000083223.13 0.297 BBS4/ENSG00000140463.9 0.297 RICTOR/ENSG00000164327.8 0.297 DNAJC18/ENSG00000170464.5 0.296 RSPRY1/ENSG00000159579.9 0.295 KAT6A/ENSG00000083168.5 0.295 ABHD16A/ENSG00000204427.7 0.294 NBEAL1/ENSG00000144426.14 0.292 DDX17/ENSG00000100201.14 0.291 CDK11A/ENSG00000008128.18 0.291 PEX1/ENSG00000127980.11 0.289 SNX13/ENSG00000071189.16 0.288 CBWD6/ENSG00000204790.8 0.287 NSFL1C/ENSG00000088833.12 0.285 RP11-159D12.2/ENSG00000264112.1 0.284 FRYL/ENSG00000075539.9 0.284 SNX24/ENSG00000064652.6 0.283 PPP1R10/ENSG00000204569.5 0.282 TRAF3IP2-AS1/ENSG00000231889.2 0.281 DNAJB11/ENSG00000090520.6 0.28 SF1/ENSG00000168066.16 0.28 CCZ1B/ENSG00000146574.10 0.279 TOPBP1/ENSG00000163781.8 0.279 EFNA5/ENSG00000184349.8 0.278 TP53BP1/ENSG00000067369.9 0.276 ALG13/ENSG00000101901.6 0.276 AP000462.1/ENSG00000256315.1 0.276 EGR1/ENSG00000120738.7 0.275 CTD-2003C8.1/ENSG00000247271.2 0.275 RP11-488C13.5/ENSG00000258301.2 0.274 RAD54L2/ENSG00000164080.8 0.273 CRLF3/ENSG00000176390.10 0.273 MPHOSPH9/ENSG00000051825.9 0.273 PPOX/ENSG00000143224.12 0.273 AGO3/ENSG00000126070.13 0.271 APP/ENSG00000142192.16 0.271 SLC35F5/ENSG00000115084.8 0.269 SLC25A37/ENSG00000147454.9 0.269 MPRIP-AS1/ENSG00000225442.2 0.269 GTF3C3/ENSG00000119041.6 0.269 ZNF266/ENSG00000174652.13 0.268 FAM208B/ENSG00000108021.15 0.266 CLASP2/ENSG00000163539.11 0.266 DNAJB9/ENSG00000128590.4 0.263 USP54/ENSG00000166348.13 0.263 OSCP1/ENSG00000116885.14 0.263 AC005154.6/ENSG00000196295.6 0.263 QSER1/ENSG00000060749.10 0.261 UBXN4/ENSG00000144224.12 0.261 TBC1D8B/ENSG00000133138.15 0.261 SPPL3/ENSG00000157837.11 0.26 RP11-583F2.1/ENSG00000264057.1 0.26 IK/ENSG00000113141.10 0.259 HBS1L/ENSG00000112339.10 0.259 RP11-640M9.2/ENSG00000225241.3 0.258 ATF6/ENSG00000118217.5 0.258 HPS4/ENSG00000100099.16 0.257 CHKA/ENSG00000110721.7 0.256 MORF4L2/ENSG00000123562.11 0.255 CTC-436K13.3/ENSG00000253424.1 0.254 EVL/ENSG00000196405.8 0.254 RC3H1/ENSG00000135870.7 0.253 SETX/ENSG00000107290.9 0.252 LONP2/ENSG00000102910.8 0.252 VEZT/ENSG00000028203.13 0.251 RNFT1/ENSG00000189050.10 0.25 AC005562.1/ENSG00000214719.5 Overrepresented GO terms in EP #20: Term Pvalue ribonucleoprotein complex subunit organization 3.81E-06 nucleic acid metabolic process 6.22E-06 regulation of cellular macromolecule biosynthetic process 3.41E-05 regulation of cellular amide metabolic process 7.09E-05 heterocycle metabolic process 0.000112183 cellular aromatic compound metabolic process 0.000180401 regulation of biosynthetic process 0.000311604 negative regulation of translation 0.000342552 cellular macromolecular complex assembly 0.000387621 cellular macromolecule catabolic process 0.000472955 posttranscriptional regulation of gene expression 0.000499337 cellular nitrogen compound biosynthetic process 0.000567177 organic cyclic compound metabolic process 0.000899853 mRNA splice site selection 0.001117658 "transcription, DNA-templated " 0.00370123 RNA biosynthetic process 0.004284727 protein localization to Golgi apparatus 0.004525445 nitrogen compound metabolic process 0.005899817 negative regulation of nitrogen compound metabolic process 0.007307476 regulation of gene expression 0.007381839 posttranscriptional gene silencing by RNA 0.009180527 regulation of cytoplasmic mRNA processing body assembly 0.009581884 stress granule assembly 0.009581884 stem cell population maintenance 0.010374012 regulation of nucleobase-containing compound metabolic process 0.013226291 regulation of mRNA metabolic process 0.015916606 "regulation of gene expression, epigenetic " 0.016059151 "mRNA splicing, via spliceosome " 0.016416841 ribonucleoprotein complex biogenesis 0.016717539 regulation of nucleic acid-templated transcription 0.016969193 negative regulation of macromolecule biosynthetic process 0.018598744 "RNA splicing, via transesterification reactions " 0.018690503 mRNA metabolic process 0.020012022 transport along microtubule 0.023722629 peptide biosynthetic process 0.025286605 RNA processing 0.02635989 proteolysis involved in cellular protein catabolic process 0.02736703 cellular component organization 0.029200301 regulation of organelle organization 0.035148821 intracellular transport 0.035219592 positive regulation of multicellular organism growth 0.036570614 protein modification by small protein conjugation or removal 0.036844798 regulation of transcription from RNA polymerase II promoter 0.040092836 negative regulation of cellular biosynthetic process 0.041770893 gene silencing 0.041834374 organic substance catabolic process 0.043087452 ubiquitin-dependent protein catabolic process 0.043220384 cellular response to topologically incorrect protein 0.046296128 microtubule anchoring at centrosome 0.047980055 --------------------------------------------- "EP #21: 49 cells, 34 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0158730158730159, stage2_: 0.0441176470588235, stage3_: 0.0857142857142857, St4_3_: 0.137931034482759, stage4: 0.0428571428571429, St5_3_: 0.0821917808219178, stage5_: 0.078125, stage6.2_: 0.024390243902439, stage6.7_: 0.0789473684210526, stage6.14_: 0.0746268656716418, " Top Genes: 2.024 RP11-713H12.2/ENSG00000270606.1 1.84 RP11-713H12.1/ENSG00000244604.1 0.465 NAT1/ENSG00000171428.9 0.461 RP11-105C19.1/ENSG00000260905.1 0.445 DICER1-AS1/ENSG00000235706.3 0.436 LONRF1/ENSG00000154359.8 0.386 KDM4C/ENSG00000107077.13 0.368 RP11-1105G2.3/ENSG00000258365.1 0.365 SEC31B/ENSG00000075826.12 0.351 RP11-93L9.1/ENSG00000249464.1 0.34 COPG1/ENSG00000181789.10 0.335 RP11-767L7.1/ENSG00000239835.1 0.334 TSSC2/ENSG00000223756.2 0.334 RP11-159G9.5/ENSG00000229729.3 0.32 ZBTB26/ENSG00000171448.8 0.319 CEP44/ENSG00000164118.8 0.319 WWOX/ENSG00000186153.12 0.319 CTD-3195I5.1/ENSG00000262758.1 0.312 ZNF114/ENSG00000178150.4 0.31 TMPRSS2/ENSG00000184012.7 0.309 RP11-3D4.3/ENSG00000259408.1 0.284 DHRS7B/ENSG00000109016.13 0.283 RP11-123K19.1/ENSG00000224842.2 0.283 ULK2/ENSG00000083290.15 0.281 VN1R1/ENSG00000178201.3 0.275 L3MBTL4/ENSG00000154655.10 0.264 PPIAP16/ENSG00000213509.4 0.263 NABP2/ENSG00000139579.8 0.257 KRT8P39/ENSG00000233560.2 0.257 AC090519.7/ENSG00000203576.1 0.257 RP11-771F20.1/ENSG00000239344.1 0.255 DCP1B/ENSG00000151065.9 0.252 RP11-133N21.7/ENSG00000257243.1 0.25 SPRY2/ENSG00000136158.6 Overrepresented GO terms in EP #21: Term Pvalue NA NA --------------------------------------------- "EP #22: 90 cells, 165 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0.0114942528735632, stage4: 0.5, St5_3_: 0.0958904109589041, stage5_: 0.390625, stage6.2_: 0.158536585365854, stage6.7_: 0.0657894736842105, stage6.14_: 0.0597014925373134, " Top Genes: 2.779 GC/ENSG00000145321.8 2.337 TM4SF4/ENSG00000169903.6 1.871 AL590714.1/ENSG00000268387.1 1.786 SEBOX/ENSG00000109072.7 1.785 APOA2/ENSG00000158874.6 1.761 ALDH1A1/ENSG00000165092.8 1.74 AMBP/ENSG00000106927.7 1.661 SCG2/ENSG00000171951.4 1.323 SERPINA1/ENSG00000197249.8 1.292 ANKS1B/ENSG00000185046.14 1.292 C22ORF42/ENSG00000205856.3 1.259 RGS2/ENSG00000116741.6 1.257 S100A10/ENSG00000197747.4 1.219 APOC3/ENSG00000110245.7 1.214 PLS3/ENSG00000102024.11 1.178 SNCG/ENSG00000173267.9 1.161 CDH18/ENSG00000145526.7 1.146 TTR/ENSG00000118271.5 1.135 APOA1/ENSG00000118137.5 1.06 RP11-21F16.1/ENSG00000267586.2 1.054 NEFM/ENSG00000104722.9 1.052 GUSBP3/ENSG00000253203.2 1.032 KCTD12/ENSG00000178695.4 1.009 PKIB/ENSG00000135549.8 0.987 CLU/ENSG00000120885.15 0.969 IDH1/ENSG00000138413.9 0.967 RP11-363E7.4/ENSG00000260912.1 0.951 PDZK1/ENSG00000174827.9 0.945 DHRS3/ENSG00000162496.4 0.922 ZDHHC8P1/ENSG00000133519.8 0.868 RP11-974F13.6/ENSG00000250763.1 0.834 GUSBP1/ENSG00000183666.11 0.817 DDC/ENSG00000132437.13 0.779 HIST1H2BK/ENSG00000197903.6 0.744 RP11-1023L17.1/ENSG00000215158.5 0.734 PEMT/ENSG00000133027.13 0.722 DLK1/ENSG00000185559.9 0.7 ADH1A/ENSG00000187758.3 0.666 ACAT2/ENSG00000120437.7 0.658 RP11-98J23.2/ENSG00000198237.7 0.619 GAST/ENSG00000184502.3 0.61 GUSBP2/ENSG00000241549.4 0.603 PDGFA/ENSG00000197461.9 0.601 GAS2L3/ENSG00000139354.6 0.566 TFF3/ENSG00000160180.14 0.563 HIPK3/ENSG00000110422.7 0.557 GSTM2/ENSG00000213366.7 0.555 NRP1/ENSG00000099250.12 0.553 GUCA2B/ENSG00000044012.3 0.551 AC090627.1/ENSG00000235300.3 0.542 ANXA4/ENSG00000196975.9 0.535 ATP2B1/ENSG00000070961.10 0.53 KRT18/ENSG00000111057.6 0.527 ID2/ENSG00000115738.5 0.526 MPC2/ENSG00000143158.6 0.521 GSKIP/ENSG00000100744.10 0.516 GPX7/ENSG00000116157.5 0.514 NEBL/ENSG00000078114.14 0.511 CPM/ENSG00000135678.7 0.501 DIRAS3/ENSG00000162595.4 0.495 UCP2/ENSG00000175567.3 0.492 TSTD1/ENSG00000215845.6 0.49 FKBP1B/ENSG00000119782.9 0.48 VPS25/ENSG00000131475.2 0.479 RP11-1415C14.4/ENSG00000254701.2 0.473 AAED1/ENSG00000158122.7 0.471 TRIM2/ENSG00000109654.10 0.471 HMGB2/ENSG00000164104.7 0.466 SEZ6L/ENSG00000100095.14 0.453 TMEM14A/ENSG00000096092.5 0.45 AS3MT/ENSG00000214435.3 0.45 ID3/ENSG00000117318.8 0.441 PLXNC1/ENSG00000136040.4 0.439 RALYL/ENSG00000184672.7 0.435 GTF2H2/ENSG00000145736.10 0.433 OCLN/ENSG00000197822.6 0.432 ABLIM1/ENSG00000099204.14 0.431 "AC011897.1,FAM84A/ENSG00000162981.12" 0.427 FAM172A/ENSG00000113391.12 0.427 STARD7/ENSG00000084090.9 0.426 IFI27L2/ENSG00000119632.3 0.425 GUSBP9/ENSG00000215630.5 0.424 AC009961.3/ENSG00000226266.1 0.421 HABP2/ENSG00000148702.10 0.419 TTC29/ENSG00000137473.13 0.406 AC068535.3/ENSG00000225765.1 0.404 MRPS5/ENSG00000144029.7 0.402 ROBO1/ENSG00000169855.15 0.4 MAOA/ENSG00000189221.5 0.399 CMC2/ENSG00000103121.4 0.398 ID1/ENSG00000125968.7 0.395 TBL1XR1/ENSG00000177565.11 0.392 EFNA5/ENSG00000184349.8 0.391 FABP1/ENSG00000163586.5 0.387 FABP7/ENSG00000164434.7 0.386 ASCC3/ENSG00000112249.9 0.385 CALD1/ENSG00000122786.15 0.385 GRIK2/ENSG00000164418.15 0.385 THSD7A/ENSG00000005108.10 0.384 SEC22A/ENSG00000121542.7 0.384 CASK/ENSG00000147044.15 0.383 GALT/ENSG00000213930.7 0.383 NRCAM/ENSG00000091129.15 0.381 CD36/ENSG00000135218.13 0.376 SCN3A/ENSG00000153253.10 0.376 ITIH1/ENSG00000055957.6 0.373 RP11-103G8.2/ENSG00000240137.1 0.369 CALML4/ENSG00000129007.10 0.366 CXORF57/ENSG00000147231.9 0.365 AKAP12/ENSG00000131016.12 0.364 C10ORF32/ENSG00000166275.11 0.361 RP11-444D3.1/ENSG00000255864.1 0.357 FBXL5/ENSG00000118564.10 0.341 RFX2/ENSG00000087903.8 0.34 RP11-6N17.6/ENSG00000264019.1 0.339 SOAT1/ENSG00000057252.8 0.339 GAP43/ENSG00000172020.8 0.339 IRF9/ENSG00000213928.4 0.339 ZC3HC1/ENSG00000091732.11 0.338 CNTNAP2/ENSG00000174469.13 0.335 IGFBP5/ENSG00000115461.4 0.332 SFRP1/ENSG00000104332.7 0.33 NAIP/ENSG00000249437.3 0.321 RP11-279F6.1/ENSG00000245750.3 0.32 SMYD3/ENSG00000185420.14 0.314 TMSB4X/ENSG00000205542.6 0.312 ANK1/ENSG00000029534.15 0.311 FGF13/ENSG00000129682.9 0.307 ONECUT3/ENSG00000205922.4 0.307 YPEL3/ENSG00000090238.7 0.307 ATP9A/ENSG00000054793.9 0.305 SOX5/ENSG00000134532.11 0.303 RP11-618K13.2/ENSG00000255498.1 0.303 TMEM144/ENSG00000164124.6 0.302 DUSP1/ENSG00000120129.5 0.302 SLC25A12/ENSG00000115840.9 0.297 MRPL27/ENSG00000108826.11 0.296 RP11-499F3.2/ENSG00000259692.1 0.296 LRRC16A/ENSG00000079691.15 0.295 ASCL1/ENSG00000139352.3 0.293 LMO3/ENSG00000048540.10 0.293 SSNA1/ENSG00000176101.7 0.291 IRX2/ENSG00000170561.8 0.289 DHCR24/ENSG00000116133.7 0.287 FAM171B/ENSG00000144369.8 0.283 ANK3/ENSG00000151150.15 0.283 CSNK1G3/ENSG00000151292.13 0.281 NPSR1-AS1/ENSG00000197085.7 0.278 MYT1L/ENSG00000186487.13 0.276 GTF2H2B/ENSG00000226259.6 0.275 USH1C/ENSG00000006611.10 0.274 FSIP2/ENSG00000188738.9 0.271 RAMP1/ENSG00000132329.6 0.27 RNF217/ENSG00000146373.11 0.27 HLA-DQA2/ENSG00000237541.3 0.263 CNOT8/ENSG00000155508.9 0.262 DPY19L3/ENSG00000178904.12 0.261 ABT1/ENSG00000146109.3 0.261 OSTF1/ENSG00000134996.11 0.26 PNPO/ENSG00000108439.5 0.258 TMTC3/ENSG00000139324.7 0.256 FAM110B/ENSG00000169122.7 0.255 UNC80/ENSG00000144406.13 0.253 GABRB3/ENSG00000166206.8 0.252 EBP/ENSG00000147155.6 Overrepresented GO terms in EP #22: Term Pvalue negative regulation of very-low-density lipoprotein particle remodeling 2.20E-05 negative regulation of lipase activity 0.000172189 reverse cholesterol transport 0.000308943 neutral lipid catabolic process 0.000347425 transmission of nerve impulse 0.000520296 negative regulation of osteoblast differentiation 0.000533193 plasma lipoprotein particle assembly 0.000644987 glycerolipid catabolic process 0.001266322 negative regulation of apoptotic process 0.001533613 high-density lipoprotein particle clearance 0.001780229 response to chemical 0.002258569 triglyceride-rich lipoprotein particle remodeling 0.002527286 negative regulation of cholesterol import 0.002613537 triglyceride catabolic process 0.003209998 negative regulation of catalytic activity 0.003388377 intestinal lipid absorption 0.003453303 epithelial cell proliferation 0.003599158 diterpenoid metabolic process 0.003826789 negative regulation of cell death 0.005147648 phospholipid efflux 0.005911191 steroid esterification 0.005911191 cholesterol esterification 0.005911191 positive regulation of cell-substrate adhesion 0.006192015 negative regulation of protein secretion 0.006192015 regulation of sterol import 0.007796596 platelet degranulation 0.009096916 high-density lipoprotein particle remodeling 0.009287155 acylglycerol metabolic process 0.010097723 positive regulation of stress fiber assembly 0.010832469 neurogenesis 0.011666149 protein localization 0.011738499 single-organism metabolic process 0.01198561 cholesterol efflux 0.011991071 negative chemotaxis 0.011991071 regeneration 0.012323529 response to wounding 0.013526775 regulation of actin filament bundle assembly 0.015308512 substrate-dependent cerebral cortex tangential migration 0.015505717 cholesterol biosynthetic process via desmosterol 0.015505717 cholesterol biosynthetic process via lathosterol 0.015505717 negative regulation of B cell differentiation 0.015505717 cell recognition 0.015720204 alcohol metabolic process 0.015932518 positive regulation of cell morphogenesis involved in differentiation 0.017249255 localization 0.017755753 organophosphate ester transport 0.018397095 response to organic cyclic compound 0.018693557 lipid digestion 0.019289988 regulation of phosphate metabolic process 0.019414966 developmental process 0.020279085 isoprenoid metabolic process 0.020653678 actin filament bundle organization 0.020653678 regulation of substrate adhesion-dependent cell spreading 0.020878861 response to vitamin 0.021932548 cellular oxidant detoxification 0.021932548 retinal ganglion cell axon guidance 0.022552767 regulation of cellular component organization 0.02553604 negative regulation of cytokine secretion involved in immune response 0.025697981 regulation of intestinal cholesterol absorption 0.025697981 regulation of Cdc42 protein signal transduction 0.025697981 asymmetric neuroblast division 0.025697981 regulation of smooth muscle cell migration 0.026733258 regulation of insulin secretion involved in cellular response to glucose stimulus 0.026733258 taxis 0.027210831 regulation of biological quality 0.028953593 protein-lipid complex remodeling 0.030087937 detoxification 0.030504439 regulation of cell-matrix adhesion 0.032145516 axon development 0.033784856 negative regulation of signal transduction 0.035039474 organic hydroxy compound transport 0.036930347 sterol import 0.037156764 regulation of neuron death 0.03737483 axon choice point recognition 0.038331011 secretion by cell 0.039418303 cerebral cortex development 0.041355966 positive regulation of lipid catabolic process 0.044103432 regulation of protein metabolic process 0.04703874 cellular component assembly 0.047417035 regulation of extent of cell growth 0.047744558 negative regulation of transporter activity 0.047875141 retinol metabolic process 0.049546267 negative regulation of MAPK cascade 0.049676653 --------------------------------------------- "EP #23: 105 cells, 89 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0.0147058823529412, stage3_: 0.242857142857143, St4_3_: 0.0459770114942529, stage4: 0.542857142857143, St5_3_: 0.191780821917808, stage5_: 0.125, stage6.2_: 0.121951219512195, stage6.7_: 0.0789473684210526, stage6.14_: 0.104477611940299, " Top Genes: 2.672 SPINK1/ENSG00000164266.6 1.978 DLK1/ENSG00000185559.9 1.941 IGF2/ENSG00000167244.12 1.74 AMBP/ENSG00000106927.7 1.656 AC132217.4/ENSG00000240801.1 1.649 SERPINA1/ENSG00000197249.8 1.571 ANXA4/ENSG00000196975.9 1.329 CLU/ENSG00000120885.15 1.313 TM4SF4/ENSG00000169903.6 1.31 FLRT2/ENSG00000185070.6 1.053 SEBOX/ENSG00000109072.7 1.034 RP11-325F22.5/ENSG00000225329.1 1.006 SOX9/ENSG00000125398.5 0.99 GSTM3/ENSG00000134202.6 0.869 C14ORF105/ENSG00000100557.5 0.825 ID3/ENSG00000117318.8 0.815 ID2/ENSG00000115738.5 0.721 F3/ENSG00000117525.9 0.695 SLC4A4/ENSG00000080493.9 0.686 MEIS1/ENSG00000143995.14 0.654 SORBS2/ENSG00000154556.13 0.645 FN1/ENSG00000115414.14 0.64 CDKN1C/ENSG00000129757.8 0.633 RP11-834C11.4/ENSG00000250742.1 0.629 WASF3/ENSG00000132970.8 0.615 PLSCR1/ENSG00000188313.8 0.594 PHGDH/ENSG00000092621.7 0.57 CKB/ENSG00000166165.8 0.562 ONECUT1/ENSG00000169856.6 0.547 MEST/ENSG00000106484.9 0.544 ALDH3A2/ENSG00000072210.14 0.54 CHST9/ENSG00000154080.8 0.517 AKAP7/ENSG00000118507.11 0.503 HMGA2/ENSG00000149948.9 0.499 PDE3A/ENSG00000172572.6 0.499 SEC11C/ENSG00000166562.4 0.48 HOGA1/ENSG00000241935.4 0.461 LAP3/ENSG00000002549.7 0.447 GNL2/ENSG00000134697.7 0.444 ATP10D/ENSG00000145246.9 0.43 SVIL/ENSG00000197321.10 0.418 STAT1/ENSG00000115415.14 0.418 TTLL7/ENSG00000137941.12 0.397 GPR126/ENSG00000112414.10 0.395 CALD1/ENSG00000122786.15 0.394 AL358113.1/ENSG00000269295.1 0.389 CRYZ/ENSG00000116791.9 0.388 GMNN/ENSG00000112312.5 0.386 CCDC101/ENSG00000176476.4 0.382 ACSM3/ENSG00000005187.7 0.379 SLC44A3/ENSG00000143036.12 0.379 DUSP6/ENSG00000139318.7 0.368 ZBTB20/ENSG00000181722.11 0.36 C8ORF47/ENSG00000177459.6 0.359 RP11-30B1.1/ENSG00000224593.1 0.359 CADPS/ENSG00000163618.13 0.357 RP11-1143G9.4/ENSG00000257764.2 0.354 MTERF/ENSG00000127989.8 0.351 ITFG2/ENSG00000111203.7 0.345 HABP2/ENSG00000148702.10 0.327 CCDC167/ENSG00000198937.8 0.326 BTG1/ENSG00000133639.3 0.314 FGB/ENSG00000171564.7 0.307 LYPD6B/ENSG00000150556.12 0.304 CAMK2N1/ENSG00000162545.5 0.302 CPA2/ENSG00000158516.7 0.295 FRMD6/ENSG00000139926.11 0.292 VAMP8/ENSG00000118640.6 0.292 BICC1/ENSG00000122870.7 0.289 LSAMP/ENSG00000185565.6 0.283 UBQLN4/ENSG00000160803.6 0.283 VIL1/ENSG00000127831.6 0.282 SIVA1/ENSG00000184990.8 0.279 SPOCK1/ENSG00000152377.8 0.279 CCND2/ENSG00000118971.3 0.278 AC107016.1/ENSG00000225410.1 0.27 CDH6/ENSG00000113361.8 0.269 IFNGR2/ENSG00000159128.10 0.267 RBP1/ENSG00000114115.5 0.267 PLA2G16/ENSG00000176485.6 0.266 IGDCC4/ENSG00000103742.7 0.263 WDR6/ENSG00000178252.12 0.261 HDAC6/ENSG00000094631.14 0.26 DECR1/ENSG00000104325.2 0.259 TOX3/ENSG00000103460.12 0.258 CCND1/ENSG00000110092.3 0.257 NDFIP1/ENSG00000131507.8 0.255 AC078941.1/ENSG00000236780.1 0.255 GLS/ENSG00000115419.8 Overrepresented GO terms in EP #23: Term Pvalue negative regulation of cellular process 0.000634453 endoderm development 0.001107896 endodermal cell differentiation 0.00220425 platelet degranulation 0.006559508 glial cell differentiation 0.007357716 regulation of multicellular organismal process 0.008329987 anatomical structure development 0.009855673 protein activation cascade 0.012935305 single-multicellular organism process 0.013978658 regulation of peptidase activity 0.015666302 negative regulation of proteolysis 0.015714523 negative regulation of catalytic activity 0.017978992 oligodendrocyte development 0.018814592 regulation of cell cycle 0.020070531 negative regulation of endopeptidase activity 0.022124891 metanephros development 0.026893229 negative regulation of epithelial cell differentiation 0.026995595 single-organism developmental process 0.032420753 xenobiotic catabolic process 0.032743357 positive regulation of cell cycle process 0.036859573 Notch signaling pathway 0.039039328 regulation of myoblast differentiation 0.043010786 negative regulation of macromolecule metabolic process 0.049046664 circulatory system development 0.049296822 acute-phase response 0.049429412 --------------------------------------------- "EP #24: 98 cells, 221 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0, stage5_: 0.21875, stage6.2_: 0.365853658536585, stage6.7_: 0.342105263157895, stage6.14_: 0.417910447761194, " Top Genes: 2.603 SLC30A8/ENSG00000164756.8 2.309 ERO1LB/ENSG00000086619.9 2.218 CALB2/ENSG00000172137.14 2.155 ASPH/ENSG00000198363.11 2.105 DLK1/ENSG00000185559.9 1.866 ACVR1C/ENSG00000123612.10 1.688 PCP4/ENSG00000183036.6 1.636 HADH/ENSG00000138796.11 1.563 PCSK1/ENSG00000175426.6 1.528 ISL1/ENSG00000016082.10 1.5 NR3C1/ENSG00000113580.10 1.453 PCDH7/ENSG00000169851.11 1.308 PAX6/ENSG00000007372.15 1.289 IGF1R/ENSG00000140443.9 1.283 MFAP4/ENSG00000166482.7 1.274 FNDC3A/ENSG00000102531.12 1.247 NEFM/ENSG00000104722.9 1.173 ABCC8/ENSG00000006071.7 1.135 GRIA4/ENSG00000152578.8 1.134 HEPACAM2/ENSG00000188175.5 1.121 CHRNA3/ENSG00000080644.11 1.104 SCG3/ENSG00000104112.4 1.069 TMED3/ENSG00000166557.8 1.001 NTM/ENSG00000182667.10 0.987 SCN7A/ENSG00000136546.9 0.972 CLU/ENSG00000120885.15 0.966 SURF4/ENSG00000148248.9 0.924 ABLIM1/ENSG00000099204.14 0.883 CHODL/ENSG00000154645.9 0.839 SPINK1/ENSG00000164266.6 0.828 ST6GALNAC5/ENSG00000117069.10 0.816 LSAMP/ENSG00000185565.6 0.797 G6PC2/ENSG00000152254.6 0.797 SPINT2/ENSG00000167642.8 0.787 DANCR/ENSG00000226950.2 0.785 RBMX2/ENSG00000134597.9 0.782 RP11-650L12.2/ENSG00000261762.1 0.769 VLDLR/ENSG00000147852.10 0.762 SEMA3A/ENSG00000075213.5 0.754 CHST9/ENSG00000154080.8 0.743 CCSER1/ENSG00000184305.10 0.742 PAPSS2/ENSG00000198682.8 0.737 AACS/ENSG00000081760.12 0.734 FKBP11/ENSG00000134285.6 0.731 CXCL12/ENSG00000107562.12 0.72 FGD4/ENSG00000139132.10 0.716 PLXNA2/ENSG00000076356.6 0.714 TSPAN5/ENSG00000168785.3 0.713 CDH1/ENSG00000039068.13 0.699 RGS9/ENSG00000108370.11 0.677 TTC8/ENSG00000165533.14 0.672 KIF5C/ENSG00000168280.12 0.666 CADM1/ENSG00000182985.11 0.662 RPSAP43/ENSG00000216471.3 0.654 FGF12/ENSG00000114279.8 0.651 FAM13C/ENSG00000148541.8 0.65 MAFB/ENSG00000204103.2 0.64 CD74/ENSG00000019582.10 0.637 CCS/ENSG00000173992.4 0.634 LMO1/ENSG00000166407.9 0.611 MAN1A1/ENSG00000111885.5 0.611 GPR119/ENSG00000147262.2 0.607 FKBP2/ENSG00000173486.8 0.598 SLC7A2/ENSG00000003989.12 0.596 PDZK1/ENSG00000174827.9 0.593 SUSD4/ENSG00000143502.9 0.59 MYH10/ENSG00000133026.8 0.589 SCARNA22/ENSG00000249784.1 0.585 IGSF1/ENSG00000147255.13 0.584 CTD-2545M3.2/ENSG00000268854.1 0.577 PLAGL1/ENSG00000118495.13 0.576 SEC24D/ENSG00000150961.10 0.574 RAB7L1/ENSG00000117280.8 0.57 MANF/ENSG00000145050.11 0.554 TIMP1/ENSG00000102265.7 0.551 MPP6/ENSG00000105926.10 0.549 PAX4/ENSG00000106331.10 0.543 HPS1/ENSG00000107521.14 0.541 RCN1/ENSG00000049449.4 0.536 PPP1R1A/ENSG00000135447.12 0.53 CUEDC2/ENSG00000107874.6 0.529 ENTPD3/ENSG00000168032.4 0.528 RP11-30B1.1/ENSG00000224593.1 0.528 IGDCC4/ENSG00000103742.7 0.525 SAMSN1/ENSG00000155307.13 0.52 RNF8/ENSG00000112130.12 0.513 CTD-2165H16.3/ENSG00000248791.1 0.503 SH3KBP1/ENSG00000147010.13 0.494 IAPP/ENSG00000121351.3 0.487 ASS1/ENSG00000130707.13 0.482 MGAT4A/ENSG00000071073.6 0.479 NECAP1/ENSG00000089818.12 0.478 MPHOSPH9/ENSG00000051825.9 0.477 ASB9/ENSG00000102048.11 0.477 CTD-2017D11.1/ENSG00000268362.1 0.475 CDH8/ENSG00000150394.9 0.466 SMARCC2/ENSG00000139613.7 0.463 LINC00643/ENSG00000186369.5 0.462 GBA3/ENSG00000249948.1 0.458 DKK3/ENSG00000050165.13 0.457 GALNT14/ENSG00000158089.10 0.455 TSC22D3/ENSG00000157514.12 0.453 GNAT3/ENSG00000214415.3 0.451 FAM213A/ENSG00000122378.9 0.446 PLCE1/ENSG00000138193.9 0.44 PLK2/ENSG00000145632.10 0.44 IFI30/ENSG00000216490.2 0.439 NPTX2/ENSG00000106236.3 0.437 CDKN1C/ENSG00000129757.8 0.437 ESYT1/ENSG00000139641.8 0.435 TMEM135/ENSG00000166575.12 0.43 SELM/ENSG00000198832.6 0.428 EBF1/ENSG00000164330.12 0.426 FAM46C/ENSG00000183508.4 0.425 SMC2/ENSG00000136824.14 0.423 ANXA10/ENSG00000109511.6 0.423 FXYD6/ENSG00000137726.11 0.423 MPP1/ENSG00000130830.9 0.422 TMEM9/ENSG00000116857.11 0.42 EPB41L4A-AS1/ENSG00000224032.2 0.42 TMEM132B/ENSG00000139364.6 0.417 TMEM123/ENSG00000152558.10 0.416 PPA1/ENSG00000180817.6 0.415 VKORC1/ENSG00000167397.10 0.414 TMEM45A/ENSG00000181458.6 0.413 MAGEH1/ENSG00000187601.3 0.412 C22ORF29/ENSG00000215012.4 0.412 VAC14/ENSG00000103043.10 0.411 PRR15L/ENSG00000167183.2 0.4 RP11-279F6.1/ENSG00000245750.3 0.397 IQSEC3/ENSG00000120645.7 0.396 CTB-63M22.1/ENSG00000229119.3 0.395 CERS6-AS1/ENSG00000227617.3 0.392 DNAJC12/ENSG00000108176.9 0.391 WSCD2/ENSG00000075035.5 0.391 TMEM196/ENSG00000173452.9 0.389 SUMF2/ENSG00000129103.13 0.388 CHRNB4/ENSG00000117971.6 0.385 LYPLAL1/ENSG00000143353.7 0.383 FKBP7/ENSG00000079150.13 0.383 PFN2/ENSG00000070087.9 0.381 KIAA1324/ENSG00000116299.12 0.38 TTC39C/ENSG00000168234.8 0.38 ASAP1/ENSG00000153317.10 0.378 LBH/ENSG00000213626.7 0.378 C12ORF10/ENSG00000139637.9 0.37 PRKCA/ENSG00000154229.7 0.368 MTUS2/ENSG00000132938.14 0.367 MIF4GD/ENSG00000125457.9 0.357 TBC1D24/ENSG00000162065.7 0.356 WLS/ENSG00000116729.9 0.354 MTMR7/ENSG00000003987.9 0.352 PPP1R1C/ENSG00000150722.6 0.352 EDARADD/ENSG00000186197.8 0.351 AKT1/ENSG00000142208.11 0.351 HECTD4/ENSG00000173064.6 0.35 SSX2IP/ENSG00000117155.12 0.349 AHCY/ENSG00000101444.7 0.346 HOPX/ENSG00000171476.17 0.342 ENO1P1/ENSG00000244457.2 0.341 ABAT/ENSG00000183044.7 0.341 DSP/ENSG00000096696.9 0.341 PKIB/ENSG00000135549.8 0.336 TMCC3/ENSG00000057704.6 0.333 CTB-191K22.5/ENSG00000267815.1 0.333 ISX/ENSG00000175329.8 0.331 CAMK2N1/ENSG00000162545.5 0.331 CTPS1/ENSG00000171793.9 0.328 DENR/ENSG00000139726.6 0.323 STARD3NL/ENSG00000010270.9 0.322 TM2D3/ENSG00000184277.8 0.322 AC104698.1/ENSG00000256261.1 0.322 SLC38A4/ENSG00000139209.11 0.32 ELP4/ENSG00000109911.13 0.316 RP11-443O13.3/ENSG00000236556.1 0.316 GAS5/ENSG00000234741.2 0.314 UCK2/ENSG00000143179.7 0.311 BCKDHA/ENSG00000248098.5 0.309 LRCH3/ENSG00000186001.8 0.308 PHC2/ENSG00000134686.12 0.308 ARHGEF3/ENSG00000163947.7 0.307 CEP170/ENSG00000143702.11 0.306 CTB-12A17.3/ENSG00000269292.1 0.304 KCNMA1/ENSG00000156113.16 0.303 SEMA3C/ENSG00000075223.9 0.303 HIBCH/ENSG00000198130.10 0.302 MLLT11/ENSG00000213190.2 0.301 ARL4C/ENSG00000188042.5 0.3 EEF2/ENSG00000167658.11 0.295 CYB5R1/ENSG00000159348.8 0.294 ELAVL2/ENSG00000107105.10 0.293 PDX1/ENSG00000139515.5 0.293 RGS16/ENSG00000143333.6 0.292 LGALS3BP/ENSG00000108679.7 0.29 TMEM54/ENSG00000121900.13 0.288 NAV2/ENSG00000166833.15 0.288 SLC17A6/ENSG00000091664.7 0.286 PHACTR2/ENSG00000112419.10 0.286 RP11-701H24.5/ENSG00000270704.1 0.285 RP11-552E20.3/ENSG00000204092.2 0.284 RP5-1033H22.2/ENSG00000224093.1 0.283 LPPR5/ENSG00000117598.7 0.283 MED27/ENSG00000160563.8 0.283 SAMD12/ENSG00000177570.9 0.28 FUT8/ENSG00000033170.12 0.28 WIPI1/ENSG00000070540.8 0.28 MAN2A1/ENSG00000112893.5 0.278 TMEM41A/ENSG00000163900.6 0.276 SGCD/ENSG00000170624.9 0.274 RP11-5N11.5/ENSG00000248378.1 0.267 ARHGAP26/ENSG00000145819.11 0.267 FNDC5/ENSG00000160097.10 0.265 CTD-2290C23.1/ENSG00000224282.3 0.263 PTPRM/ENSG00000173482.12 0.263 C19ORF10/ENSG00000074842.3 0.258 CNOT8/ENSG00000155508.9 0.257 RP11-713H12.2/ENSG00000270606.1 0.255 CTNNA2/ENSG00000066032.13 0.255 NEBL/ENSG00000078114.14 0.255 PYCR1/ENSG00000183010.12 0.25 SMAD9/ENSG00000120693.9 Overrepresented GO terms in EP #24: Term Pvalue regulation of peptide transport 0.000620923 secretion by cell 0.001009973 gland development 0.002030811 amide transport 0.002343708 regulation of peptide hormone secretion 0.002581326 N-glycan processing 0.003435366 endocrine system development 0.003513531 neuron projection development 0.003556917 single-organism process 0.00428811 response to nicotine 0.004622026 regulation of hormone levels 0.006036139 platelet degranulation 0.007727156 pancreas development 0.007845571 chaperone-mediated protein folding 0.007947699 nervous system development 0.008077665 exocrine system development 0.010669497 hormone secretion 0.012646397 synaptic transmission involved in micturition 0.014803882 regulation of axon extension involved in axon guidance 0.021035953 regulation of secretion 0.029182405 axon guidance 0.029234282 sensory system development 0.029377949 negative regulation of trophoblast cell migration 0.029377949 multicellular organism development 0.031460834 hindbrain development 0.031597095 locomotory behavior 0.031903714 regulation of protein secretion 0.033069279 positive regulation of insulin secretion 0.033625261 regulation of system process 0.039265181 neuron projection extension involved in neuron projection guidance 0.040022477 negative regulation of peptide secretion 0.048383876 dichotomous subdivision of terminal units involved in salivary gland branching 0.048583552 --------------------------------------------- "EP #25: 250 cells, 364 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0.228571428571429, St5_3_: 0.136986301369863, stage5_: 0.765625, stage6.2_: 0.841463414634146, stage6.7_: 0.723684210526316, stage6.14_: 0.761194029850746, " Top Genes: 2.841 INS/ENSG00000254647.2 2.588 CRYBA2/ENSG00000163499.7 2.137 TMEM176B/ENSG00000106565.13 1.968 DDC/ENSG00000132437.13 1.855 SCG5/ENSG00000166922.4 1.76 AC132217.4/ENSG00000240801.1 1.744 TMEM176A/ENSG00000002933.3 1.697 ABCC8/ENSG00000006071.7 1.681 AMBP/ENSG00000106927.7 1.594 PCBD1/ENSG00000166228.4 1.57 TTR/ENSG00000118271.5 1.523 APOC3/ENSG00000110245.7 1.467 GUSBP3/ENSG00000253203.2 1.431 KCNK16/ENSG00000095981.6 1.428 TSPAN1/ENSG00000117472.5 1.4 IGF2/ENSG00000167244.12 1.375 PPP1R14C/ENSG00000198729.4 1.356 TPH1/ENSG00000129167.5 1.302 FXYD2/ENSG00000137731.8 1.289 SERGEF/ENSG00000129158.5 1.283 CHGA/ENSG00000100604.8 1.238 SGPL1/ENSG00000166224.12 1.206 TMEM37/ENSG00000171227.6 1.205 SLC7A8/ENSG00000092068.14 1.18 TAGLN2/ENSG00000158710.10 1.147 DUSP1/ENSG00000120129.5 1.147 HIST1H2BK/ENSG00000197903.6 1.122 KCNK17/ENSG00000124780.9 1.122 TSTD1/ENSG00000215845.6 1.113 COTL1/ENSG00000103187.5 1.09 NEUROD1/ENSG00000162992.3 1.074 TP53INP1/ENSG00000164938.9 1.049 RP11-974F13.6/ENSG00000250763.1 1.027 CALB2/ENSG00000172137.14 1.02 P4HTM/ENSG00000178467.12 1.013 FCGRT/ENSG00000104870.8 1.002 PEMT/ENSG00000133027.13 0.989 ATP6V1H/ENSG00000047249.12 0.981 CD81/ENSG00000110651.7 0.977 ACADVL/ENSG00000072778.15 0.953 MAFB/ENSG00000204103.2 0.951 IGFBP5/ENSG00000115461.4 0.919 BCAT2/ENSG00000105552.10 0.887 PTHLH/ENSG00000087494.11 0.886 OCIAD2/ENSG00000145247.7 0.885 CTB-43P18.1/ENSG00000249758.1 0.876 ORMDL3/ENSG00000172057.5 0.873 CTC-340A15.2/ENSG00000241956.5 0.853 PAX4/ENSG00000106331.10 0.849 CRISPLD1/ENSG00000121005.4 0.84 GDAP1/ENSG00000104381.8 0.834 C12ORF10/ENSG00000139637.9 0.834 APOA1/ENSG00000118137.5 0.829 MSRB1/ENSG00000198736.7 0.828 USH1C/ENSG00000006611.10 0.799 LINC00261/ENSG00000259974.1 0.786 SLC29A1/ENSG00000112759.12 0.785 DCAF13/ENSG00000164934.9 0.779 F10/ENSG00000126218.7 0.776 FAM214A/ENSG00000047346.8 0.77 KIF9/ENSG00000088727.8 0.769 DANCR/ENSG00000226950.2 0.766 GSTM2/ENSG00000213366.7 0.761 RPP21/ENSG00000241370.1 0.757 VMP1/ENSG00000062716.5 0.753 LLGL2/ENSG00000073350.9 0.741 C19ORF70/ENSG00000174917.4 0.736 UCP2/ENSG00000175567.3 0.733 C1ORF122/ENSG00000197982.11 0.732 FARP1/ENSG00000152767.11 0.729 IFI6/ENSG00000126709.10 0.714 SMC2/ENSG00000136824.14 0.706 RPL22L1/ENSG00000163584.13 0.7 UCHL1/ENSG00000154277.8 0.7 SMARCA2/ENSG00000080503.15 0.698 RASSF6/ENSG00000169435.9 0.696 PLP2/ENSG00000102007.6 0.688 GCH1/ENSG00000131979.14 0.686 PPP1R1A/ENSG00000135447.12 0.685 SMIM5/ENSG00000204323.5 0.681 TFDP2/ENSG00000114126.13 0.68 SSTR2/ENSG00000180616.4 0.671 AACS/ENSG00000081760.12 0.67 ETFDH/ENSG00000171503.7 0.66 FKBP1B/ENSG00000119782.9 0.656 GCHFR/ENSG00000137880.4 0.652 RP11-161H23.5/ENSG00000258232.2 0.649 FMNL2/ENSG00000157827.15 0.647 STX1A/ENSG00000106089.7 0.644 DALRD3/ENSG00000178149.12 0.64 PLAC8/ENSG00000145287.6 0.636 S100A6/ENSG00000197956.5 0.629 MTRNR2L8/ENSG00000255823.1 0.628 F3/ENSG00000117525.9 0.627 C8ORF56/ENSG00000236939.2 0.626 COQ10A/ENSG00000135469.9 0.61 DMAP1/ENSG00000178028.9 0.609 ALKBH5/ENSG00000091542.8 0.606 RP11-660L16.2/ENSG00000254682.1 0.603 JTB/ENSG00000143543.10 0.603 RP11-98J23.2/ENSG00000198237.7 0.601 ALG2/ENSG00000119523.8 0.601 UGDH/ENSG00000109814.7 0.601 RABAC1/ENSG00000105404.6 0.6 PLEKHA1/ENSG00000107679.10 0.599 CALML4/ENSG00000129007.10 0.597 HIST1H2AC/ENSG00000180573.8 0.593 TXNL4A/ENSG00000141759.10 0.592 SLC25A3/ENSG00000075415.8 0.59 XBP1/ENSG00000100219.12 0.589 TM4SF4/ENSG00000169903.6 0.577 AIF1/ENSG00000204472.8 0.568 TOMM34/ENSG00000025772.7 0.562 COMMD3/ENSG00000148444.11 0.559 MLXIPL/ENSG00000009950.11 0.554 SAMD3/ENSG00000164483.12 0.554 RP11-123K19.1/ENSG00000224842.2 0.553 TAPBP/ENSG00000231925.7 0.552 CDC42EP3/ENSG00000163171.6 0.552 CST3/ENSG00000101439.4 0.548 CTC-535M15.1/ENSG00000253512.1 0.546 GSTK1/ENSG00000197448.9 0.545 EPHX2/ENSG00000120915.9 0.541 SPAG16/ENSG00000144451.14 0.537 AIG1/ENSG00000146416.12 0.536 VEGFA/ENSG00000112715.16 0.533 HPN/ENSG00000105707.9 0.532 MTRNR2L2/ENSG00000271043.1 0.529 BCAR3/ENSG00000137936.12 0.528 POR/ENSG00000127948.9 0.526 FEV/ENSG00000163497.2 0.521 DNAJC12/ENSG00000108176.9 0.517 FAHD1/ENSG00000180185.7 0.517 PSMD1/ENSG00000173692.8 0.516 GOLT1A/ENSG00000174567.7 0.515 STARD10/ENSG00000214530.2 0.514 DICER1/ENSG00000100697.10 0.509 STX3/ENSG00000166900.10 0.507 PRPS2/ENSG00000101911.8 0.505 RP11-21F16.1/ENSG00000267586.2 0.505 RP11-788H18.1/ENSG00000257729.1 0.504 FLYWCH2/ENSG00000162076.8 0.502 UBE2QL1/ENSG00000215218.3 0.501 FAM174B/ENSG00000185442.7 0.498 PPID/ENSG00000171497.4 0.498 SPG21/ENSG00000090487.6 0.497 PRKCH/ENSG00000027075.9 0.494 ALDOC/ENSG00000109107.9 0.493 SLCO3A1/ENSG00000176463.8 0.489 MRPS11/ENSG00000181991.11 0.488 RGS16/ENSG00000143333.6 0.486 RP11-667K14.4/ENSG00000262533.1 0.485 TXLNG2P/ENSG00000131002.7 0.478 INSM1/ENSG00000173404.3 0.476 RGS9/ENSG00000108370.11 0.475 RP11-620J15.3/ENSG00000257698.1 0.475 WFS1/ENSG00000109501.9 0.474 PLEKHB1/ENSG00000021300.9 0.473 POLD2/ENSG00000106628.6 0.468 DEF8/ENSG00000140995.12 0.465 LYSMD2/ENSG00000140280.9 0.464 DDIT3/ENSG00000175197.5 0.462 NOP16/ENSG00000048162.15 0.457 CYSTM1/ENSG00000120306.5 0.456 TMEM86B/ENSG00000180089.4 0.456 RPS6KB1/ENSG00000108443.9 0.454 IRF9/ENSG00000213928.4 0.454 RP5-1121A15.4/ENSG00000235029.1 0.451 FAM105A/ENSG00000145569.5 0.451 COX5A/ENSG00000178741.7 0.45 TMED8/ENSG00000100580.7 0.448 PITRM1/ENSG00000107959.11 0.448 FAM47E/ENSG00000189157.8 0.448 WDR45/ENSG00000196998.10 0.447 RP11-1415C14.4/ENSG00000254701.2 0.447 NHP2/ENSG00000145912.4 0.447 AHCYL1/ENSG00000168710.13 0.445 RNA28S5/ENSG00000226958.1 0.445 EVL/ENSG00000196405.8 0.444 ATP2A3/ENSG00000074370.13 0.444 HIST1H2BD/ENSG00000158373.7 0.44 APMAP/ENSG00000101474.7 0.44 COMT/ENSG00000093010.7 0.44 INSIG1/ENSG00000186480.8 0.439 MRPL17/ENSG00000158042.8 0.438 LINC00116/ENSG00000175701.6 0.436 RDH10/ENSG00000121039.5 0.431 RP11-136K7.2/ENSG00000250387.2 0.429 RBBP7/ENSG00000102054.13 0.428 REXO2/ENSG00000076043.5 0.428 MAPK3/ENSG00000102882.7 0.425 ARPC5/ENSG00000162704.11 0.424 DNPH1/ENSG00000112667.8 0.423 HNF1A-AS1/ENSG00000241388.2 0.423 ABRACL/ENSG00000146386.7 0.423 ST6GAL1/ENSG00000073849.10 0.422 NOSIP/ENSG00000142546.9 0.422 PCSK1N/ENSG00000102109.6 0.421 HIPK3/ENSG00000110422.7 0.421 CYFIP2/ENSG00000055163.14 0.421 TIMM8B/ENSG00000150779.7 0.42 VIL1/ENSG00000127831.6 0.417 C9ORF16/ENSG00000171159.4 0.417 CCDC91/ENSG00000123106.6 0.416 SLC29A4/ENSG00000164638.5 0.412 YARS/ENSG00000134684.6 0.412 ARHGAP24/ENSG00000138639.13 0.412 EPB41L4B/ENSG00000095203.10 0.409 PROC/ENSG00000115718.13 0.408 SRSF9/ENSG00000111786.4 0.407 MAP6/ENSG00000171533.7 0.406 GSTM3/ENSG00000134202.6 0.402 HSPH1/ENSG00000120694.15 0.402 TUSC3/ENSG00000104723.16 0.4 ITM2C/ENSG00000135916.11 0.398 SERPINB6/ENSG00000124570.13 0.397 RP11-1023L17.1/ENSG00000215158.5 0.397 FBXO9/ENSG00000112146.11 0.396 KCNMA1/ENSG00000156113.16 0.395 DPM3/ENSG00000179085.7 0.395 GSE1/ENSG00000131149.13 0.393 CXCL12/ENSG00000107562.12 0.391 CUL4A/ENSG00000139842.10 0.389 AHI1/ENSG00000135541.16 0.387 SSU72/ENSG00000160075.10 0.385 IMPA2/ENSG00000141401.7 0.379 DCXR/ENSG00000169738.2 0.379 WNK1/ENSG00000060237.12 0.376 PNPO/ENSG00000108439.5 0.375 CHORDC1/ENSG00000110172.7 0.375 NOL4/ENSG00000101746.11 0.374 AL139385.1/ENSG00000255831.1 0.374 GRB14/ENSG00000115290.5 0.369 REV3L/ENSG00000009413.11 0.369 ID1/ENSG00000125968.7 0.368 RP11-206L10.11/ENSG00000228794.3 0.366 RP11-489N22.3/ENSG00000269909.1 0.365 C10ORF10/ENSG00000165507.8 0.364 PROSC/ENSG00000147471.7 0.361 LCOR/ENSG00000196233.7 0.36 CNTNAP2/ENSG00000174469.13 0.359 ZNF714/ENSG00000160352.11 0.358 CTPS1/ENSG00000171793.9 0.357 ROCK1/ENSG00000067900.5 0.357 BAALC/ENSG00000164929.12 0.357 NT5C3B/ENSG00000141698.11 0.355 LDLRAP1/ENSG00000157978.7 0.351 HELLS/ENSG00000119969.10 0.351 WDR90/ENSG00000161996.13 0.351 MANBA/ENSG00000109323.4 0.35 RP11-358L16.2/ENSG00000242639.2 0.348 FBL/ENSG00000105202.3 0.348 REC8/ENSG00000100918.8 0.347 EMC7/ENSG00000134153.5 0.347 KLC1/ENSG00000126214.16 0.347 VLDLR/ENSG00000147852.10 0.346 SRM/ENSG00000116649.5 0.345 RP11-125B21.2/ENSG00000236404.4 0.344 AL035252.1/ENSG00000268302.1 0.342 GTF3C1/ENSG00000077235.13 0.337 CCDC50/ENSG00000152492.9 0.335 RAB17/ENSG00000124839.8 0.334 AIP/ENSG00000110711.4 0.333 BX936347.1/ENSG00000197180.1 0.333 CPT1C/ENSG00000169169.10 0.331 LPCAT3/ENSG00000111684.6 0.33 RFX6/ENSG00000185002.5 0.329 ST6GALNAC4/ENSG00000136840.14 0.329 MRPS12/ENSG00000128626.7 0.329 RALGAPA1/ENSG00000174373.11 0.327 PMS2P1/ENSG00000078319.7 0.325 GOLM1/ENSG00000135052.12 0.325 C9ORF135/ENSG00000204711.4 0.324 IFRD1/ENSG00000006652.9 0.322 GTF2E1/ENSG00000153767.5 0.322 RRAGA/ENSG00000155876.4 0.32 COG6/ENSG00000133103.12 0.319 VEGFB/ENSG00000173511.5 0.318 PDXP/ENSG00000241360.1 0.318 RP4-717I23.3/ENSG00000223745.3 0.318 HSD17B14/ENSG00000087076.4 0.316 ZFAND5/ENSG00000107372.8 0.316 CLINT1/ENSG00000113282.9 0.315 PAK3/ENSG00000077264.9 0.315 TFDP1/ENSG00000198176.8 0.313 EMB/ENSG00000170571.7 0.31 CDKN1C/ENSG00000129757.8 0.309 SLC25A46/ENSG00000164209.12 0.309 GLT8D1/ENSG00000016864.12 0.309 CAMK2N1/ENSG00000162545.5 0.309 ATP5E/ENSG00000124172.5 0.306 IMPDH2/ENSG00000178035.7 0.305 RASGRP1/ENSG00000172575.7 0.305 FARSA/ENSG00000179115.6 0.303 MKNK1/ENSG00000079277.15 0.302 SCGN/ENSG00000079689.9 0.302 PIGG/ENSG00000174227.11 0.302 C12ORF76/ENSG00000174456.9 0.302 MPC1/ENSG00000060762.14 0.3 LSM10/ENSG00000181817.5 0.299 DHRS4-AS1/ENSG00000215256.3 0.298 PDGFA/ENSG00000197461.9 0.297 SLC18B1/ENSG00000146409.6 0.297 SRGAP3/ENSG00000196220.10 0.297 RAB27A/ENSG00000069974.11 0.296 AK5/ENSG00000154027.14 0.295 RP11-127I20.4/ENSG00000267795.1 0.295 SLC30A8/ENSG00000164756.8 0.291 UNC45A/ENSG00000140553.12 0.291 C6ORF1/ENSG00000186577.7 0.289 TMEM101/ENSG00000091947.5 0.289 SNHG3/ENSG00000242125.1 0.288 PDZRN3/ENSG00000121440.10 0.288 PAM16/ENSG00000217930.3 0.286 GALNT14/ENSG00000158089.10 0.286 TMEM42/ENSG00000169964.5 0.286 LDOC1/ENSG00000182195.6 0.285 CCDC153/ENSG00000248712.3 0.285 TMEM200A/ENSG00000164484.7 0.285 HSD17B7/ENSG00000132196.8 0.284 DCTD/ENSG00000129187.10 0.284 TMEM190/ENSG00000160472.4 0.284 AARS/ENSG00000090861.11 0.282 FAM115A/ENSG00000198420.5 0.282 CLPTM1L/ENSG00000049656.9 0.281 COBLL1/ENSG00000082438.11 0.281 MNX1/ENSG00000130675.10 0.28 DNALI1/ENSG00000163879.9 0.28 CRELD1/ENSG00000163703.13 0.279 GUSBP2/ENSG00000241549.4 0.279 SEPHS2/ENSG00000179918.15 0.278 WDR19/ENSG00000157796.13 0.278 SLC27A5/ENSG00000083807.5 0.277 TESC/ENSG00000088992.13 0.277 DCTN3/ENSG00000137100.11 0.276 RUNX1T1/ENSG00000079102.12 0.276 NR0B1/ENSG00000169297.6 0.275 IKBKE/ENSG00000143466.8 0.271 BRI3/ENSG00000164713.5 0.271 C11ORF71/ENSG00000180425.6 0.27 ARFIP2/ENSG00000132254.8 0.27 RNASE4/ENSG00000258818.1 0.269 PSMD2/ENSG00000175166.12 0.269 KLF10/ENSG00000155090.10 0.268 GOLGA5/ENSG00000066455.8 0.266 MSL3/ENSG00000005302.13 0.265 EIF2B4/ENSG00000115211.11 0.264 ZFP36L2/ENSG00000152518.5 0.263 COG1/ENSG00000166685.6 0.262 CNGA3/ENSG00000144191.7 0.26 NFASC/ENSG00000163531.11 0.259 SYNJ2/ENSG00000078269.9 0.258 CACYBP/ENSG00000116161.13 0.258 CMPK1/ENSG00000162368.9 0.256 LEPREL4/ENSG00000141696.8 0.255 VPS13C/ENSG00000129003.11 0.255 VPS11/ENSG00000160695.10 0.255 GTF2H2/ENSG00000145736.10 0.254 STXBP5L/ENSG00000145087.8 0.254 RP11-497H16.8/ENSG00000253333.1 0.254 FTCD/ENSG00000160282.9 0.253 RAMP1/ENSG00000132329.6 0.252 ZBTB8OS/ENSG00000176261.11 0.25 MARCH8/ENSG00000165406.10 Overrepresented GO terms in EP #25: Term Pvalue organic acid metabolic process 0.000218994 single-organism biosynthetic process 0.00134782 estrogen metabolic process 0.001661567 carboxylic acid metabolic process 0.002595208 negative regulation of molecular function 0.006514392 platelet-derived growth factor receptor signaling pathway 0.006788141 vesicle-mediated transport 0.00718689 pancreatic A cell differentiation 0.009129468 regulation of fatty acid biosynthetic process 0.011797233 response to toxic substance 0.012183204 response to carbohydrate 0.016244235 organonitrogen compound metabolic process 0.016528227 response to organonitrogen compound 0.01738584 lipid homeostasis 0.017855268 organonitrogen compound biosynthetic process 0.017905857 hormone metabolic process 0.017969011 response to hexose 0.019863871 single-organism transport 0.019978814 adrenal gland development 0.020452689 regulation of biological quality 0.020871029 protein maturation by protein folding 0.021273864 Leydig cell differentiation 0.021273864 pancreas development 0.021339441 glucose homeostasis 0.023387494 regulation of cholesterol metabolic process 0.02487413 actin polymerization or depolymerization 0.027860756 ATF6-mediated unfolded protein response 0.029946941 negative regulation of hydrolase activity 0.031937629 negative regulation of fatty acid metabolic process 0.03567302 organic hydroxy compound biosynthetic process 0.037627542 establishment of localization 0.038908615 negative regulation of very-low-density lipoprotein particle remodeling 0.041654109 serotonin biosynthetic process 0.041654109 pyridoxal phosphate metabolic process 0.041654109 cellular detoxification of nitrogen compound 0.041654109 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding 0.041654109 cellular response to glucose stimulus 0.043601147 --------------------------------------------- "EP #26: 143 cells, 47 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0476190476190476, stage2_: 0.0735294117647059, stage3_: 0.0714285714285714, St4_3_: 0.28735632183908, stage4: 0.128571428571429, St5_3_: 0.287671232876712, stage5_: 0.578125, stage6.2_: 0.353658536585366, stage6.7_: 0.118421052631579, stage6.14_: 0, " Top Genes: 0.828 ZNF124/ENSG00000196418.7 0.707 ACAT2/ENSG00000120437.7 0.707 RCHY1/ENSG00000163743.9 0.664 RP5-1022P6.3/ENSG00000233578.1 0.59 C22ORF29/ENSG00000215012.4 0.579 MDM2/ENSG00000135679.17 0.528 KHDRBS3/ENSG00000131773.9 0.526 CDK5RAP1/ENSG00000101391.15 0.524 HMGCR/ENSG00000113161.11 0.504 NSDHL/ENSG00000147383.6 0.468 MYO10/ENSG00000145555.10 0.414 TMEM97/ENSG00000109084.9 0.408 TMEM41B/ENSG00000166471.6 0.405 SLC35B1/ENSG00000121073.8 0.401 RP11-701H24.5/ENSG00000270704.1 0.398 MMAB/ENSG00000139428.6 0.391 SPOCK3/ENSG00000196104.6 0.387 CTD-3236F5.1/ENSG00000240808.1 0.378 MSMO1/ENSG00000052802.8 0.374 IGF1R/ENSG00000140443.9 0.36 GAL/ENSG00000069482.6 0.359 TTC28-AS1/ENSG00000235954.2 0.355 RP11-613C6.4/ENSG00000235183.3 0.355 TSPAN2/ENSG00000134198.5 0.347 IFT46/ENSG00000118096.3 0.347 F11R/ENSG00000158769.12 0.34 AC073283.4/ENSG00000234690.2 0.334 FAM213A/ENSG00000122378.9 0.324 STRIP1/ENSG00000143093.9 0.313 RP11-611O2.5/ENSG00000257181.1 0.298 DHRS3/ENSG00000162496.4 0.296 RP11-121A13.3/ENSG00000266839.1 0.292 NTM/ENSG00000182667.10 0.29 MVD/ENSG00000167508.6 0.287 RP11-665C16.1/ENSG00000239686.1 0.284 RAB3C/ENSG00000152932.6 0.282 LDLR/ENSG00000130164.7 0.282 PPFIBP1/ENSG00000110841.9 0.28 WDR54/ENSG00000005448.12 0.275 DKK3/ENSG00000050165.13 0.272 RP5-867C24.1/ENSG00000239291.1 0.272 RNF14/ENSG00000013561.13 0.271 FDPS/ENSG00000160752.10 0.268 WI2-89927D4.1/ENSG00000248155.1 0.267 SEC16A/ENSG00000148396.14 0.262 CUEDC2/ENSG00000107874.6 0.252 EIF3C/ENSG00000184110.10 Overrepresented GO terms in EP #26: Term Pvalue cholesterol biosynthetic process 3.99E-06 secondary alcohol metabolic process 1.28E-05 sterol metabolic process 1.98E-05 steroid biosynthetic process 3.51E-05 alcohol biosynthetic process 0.000137158 isoprenoid biosynthetic process 0.00117934 regulation of glucocorticoid metabolic process 0.005709559 lipid metabolic process 0.017160768 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.022124077 response to immobilization stress 0.041980859 --------------------------------------------- "EP #27: 60 cells, 86 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0.157142857142857, St5_3_: 0.0821917808219178, stage5_: 0.265625, stage6.2_: 0.158536585365854, stage6.7_: 0.0789473684210526, stage6.14_: 0.104477611940299, " Top Genes: 2.054 GNG3/ENSG00000162188.5 1.184 PPP1R17/ENSG00000106341.6 1.041 RTN1/ENSG00000139970.12 1.009 TFF3/ENSG00000160180.14 0.9 NEBL/ENSG00000078114.14 0.887 MYT1L/ENSG00000186487.13 0.877 MAP1B/ENSG00000131711.10 0.862 CLU/ENSG00000120885.15 0.856 SPAG16/ENSG00000144451.14 0.818 PCSK1/ENSG00000175426.6 0.805 LCORL/ENSG00000178177.9 0.8 SNCG/ENSG00000173267.9 0.795 GRIA4/ENSG00000152578.8 0.784 CTC-535M15.1/ENSG00000253512.1 0.76 CA2/ENSG00000104267.5 0.748 AC004540.4/ENSG00000225792.1 0.709 TCEAL7/ENSG00000182916.7 0.653 GAP43/ENSG00000172020.8 0.626 FABP7/ENSG00000164434.7 0.618 SNAP25/ENSG00000132639.8 0.593 SYT11/ENSG00000132718.7 0.569 MARCKSL1/ENSG00000175130.6 0.561 MAP2K6/ENSG00000108984.9 0.555 INA/ENSG00000148798.5 0.537 FGF9/ENSG00000102678.6 0.529 EMC3/ENSG00000125037.8 0.522 NNAT/ENSG00000053438.7 0.491 KIF5A/ENSG00000155980.7 0.488 TSHR/ENSG00000165409.11 0.483 CTC-304I17.3/ENSG00000265775.1 0.475 SLC35A1/ENSG00000164414.12 0.469 ANK2/ENSG00000145362.12 0.465 AC063980.1/ENSG00000249612.1 0.459 SERGEF/ENSG00000129158.5 0.456 PAFAH1B3/ENSG00000079462.3 0.451 SGCD/ENSG00000170624.9 0.446 PRKAG2/ENSG00000106617.9 0.434 KRT7/ENSG00000135480.10 0.428 CASZ1/ENSG00000130940.10 0.427 SYT13/ENSG00000019505.3 0.418 GNAI2/ENSG00000114353.12 0.411 KIAA0408/ENSG00000189367.10 0.405 FAXC/ENSG00000146267.10 0.403 DCTPP1/ENSG00000179958.4 0.398 MAST4/ENSG00000069020.14 0.396 CRMP1/ENSG00000072832.10 0.387 FAM89A/ENSG00000182118.5 0.368 HN1/ENSG00000189159.11 0.36 EBF1/ENSG00000164330.12 0.354 AC007098.1/ENSG00000226605.1 0.351 ENO2/ENSG00000111674.3 0.35 HDAC9/ENSG00000048052.16 0.343 HSD17B14/ENSG00000087076.4 0.335 AKAP6/ENSG00000151320.6 0.321 VIM/ENSG00000026025.9 0.319 FGFR1/ENSG00000077782.15 0.316 NETO1/ENSG00000166342.14 0.316 CTNNBIP1/ENSG00000178585.10 0.315 ASS1/ENSG00000130707.13 0.309 MYO1D/ENSG00000176658.11 0.309 RAB8B/ENSG00000166128.8 0.308 CA13/ENSG00000185015.3 0.307 PAPPA2/ENSG00000116183.6 0.306 RCAN1/ENSG00000159200.12 0.303 HIST1H2AG/ENSG00000196787.2 0.301 RP11-71H17.7/ENSG00000260391.2 0.298 CLASP2/ENSG00000163539.11 0.292 VCAN/ENSG00000038427.11 0.286 C1ORF228/ENSG00000198520.6 0.283 SLC38A11/ENSG00000169507.5 0.282 CTD-3116E22.4/ENSG00000267106.1 0.28 AC024560.3/ENSG00000214135.4 0.277 ECE2/ENSG00000145194.13 0.273 CTD-2636A23.2/ENSG00000261604.1 0.272 TYW1B/ENSG00000254184.2 0.268 NSF/ENSG00000073969.14 0.266 CHAC1/ENSG00000128965.7 0.263 STMN4/ENSG00000015592.12 0.262 PHAX/ENSG00000164902.9 0.262 RP11-265D17.2/ENSG00000254680.1 0.26 STON2/ENSG00000140022.5 0.256 ZFYVE20/ENSG00000131381.8 0.252 CCZ1B/ENSG00000146574.10 0.252 RP13-104F24.3/ENSG00000265298.1 0.251 PHACTR3/ENSG00000087495.12 0.25 RP11-613C6.4/ENSG00000235183.3 Overrepresented GO terms in EP #27: Term Pvalue central nervous system development 0.00247984 multicellular organismal process 0.004506891 cell differentiation 0.005319485 multicellular organism development 0.006354267 positive regulation of cardiac muscle tissue growth 0.007632831 muscle cell development 0.013209246 secretion 0.013795783 regulation of mesenchymal cell proliferation 0.017119861 establishment of vesicle localization 0.017545816 single-organism cellular localization 0.024914029 vesicle-mediated transport in synapse 0.024959088 regulation of transport 0.027160876 positive regulation of organ growth 0.027725081 anterograde trans-synaptic signaling 0.029001787 synaptic signaling 0.029001787 regulation of secretion by cell 0.030522392 lung-associated mesenchyme development 0.031749741 cardiac muscle tissue development 0.036377046 single-organism membrane fusion 0.039333153 synaptic vesicle cycle 0.041577011 modulation of synaptic transmission 0.044998928 exocytosis 0.045895982 regulation of heart growth 0.047302556 regulation of striated muscle tissue development 0.047952166 --------------------------------------------- "EP #28: 63 cells, 174 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0.0571428571428571, St4_3_: 0.471264367816092, stage4: 0.114285714285714, St5_3_: 0.123287671232877, stage5_: 0, stage6.2_: 0, stage6.7_: 0.0131578947368421, stage6.14_: 0, " Top Genes: 2.442 C10ORF10/ENSG00000165507.8 2.368 ISL1/ENSG00000016082.10 1.96 AMPH/ENSG00000078053.12 1.906 SEBOX/ENSG00000109072.7 1.777 RGS5/ENSG00000143248.7 1.768 ST18/ENSG00000147488.7 1.576 NEUROD1/ENSG00000162992.3 1.526 ALDH1A1/ENSG00000165092.8 1.231 CTD-2545M3.8/ENSG00000268518.1 1.162 SLC2A1/ENSG00000117394.15 1.161 ENPP1/ENSG00000197594.7 1.11 TAGLN3/ENSG00000144834.8 1.108 APOA1/ENSG00000118137.5 1.07 EPHA4/ENSG00000116106.7 1.066 FLRT2/ENSG00000185070.6 1.062 SST/ENSG00000157005.3 1.039 STARD4-AS1/ENSG00000246859.2 1.028 TMEM256P2/ENSG00000226726.1 0.989 PRCP/ENSG00000137509.5 0.965 KRT19/ENSG00000171345.9 0.962 RGS4/ENSG00000117152.9 0.956 SEMA3A/ENSG00000075213.5 0.928 CRH/ENSG00000147571.3 0.92 RAP2B/ENSG00000181467.2 0.903 RAB3C/ENSG00000152932.6 0.901 NUDT4/ENSG00000173598.9 0.876 CHL1/ENSG00000134121.5 0.868 SRP19/ENSG00000153037.7 0.862 MPRIP-AS1/ENSG00000225442.2 0.837 CTSC/ENSG00000109861.11 0.82 PSMF1/ENSG00000125818.12 0.819 ZEB2/ENSG00000169554.11 0.814 SCG3/ENSG00000104112.4 0.806 DPP10/ENSG00000175497.12 0.801 AAED1/ENSG00000158122.7 0.765 GRSF1/ENSG00000132463.9 0.761 RP11-642D21.1/ENSG00000254141.1 0.76 DCAKD/ENSG00000172992.7 0.758 ABCA5/ENSG00000154265.11 0.744 MGAT4C/ENSG00000182050.9 0.726 ALCAM/ENSG00000170017.8 0.709 ZNF330/ENSG00000109445.6 0.697 USP11/ENSG00000102226.4 0.689 SPTSSB/ENSG00000196542.4 0.68 FH/ENSG00000091483.6 0.679 ACOT7/ENSG00000097021.14 0.663 NEFM/ENSG00000104722.9 0.651 FLRT3/ENSG00000125848.9 0.644 GUSBP2/ENSG00000241549.4 0.596 VCAN/ENSG00000038427.11 0.584 CTB-95D12.1/ENSG00000270442.1 0.582 ATAT1/ENSG00000137343.13 0.576 TNFRSF19/ENSG00000127863.11 0.572 DMD/ENSG00000198947.9 0.563 DPCD/ENSG00000166171.8 0.559 INPP1/ENSG00000151689.8 0.558 RRAGD/ENSG00000025039.9 0.557 RP11-306K13.1/ENSG00000224348.2 0.557 BRD7P3/ENSG00000169075.7 0.555 HMGB2/ENSG00000164104.7 0.553 CXORF57/ENSG00000147231.9 0.549 B3GNT7/ENSG00000156966.6 0.545 ANKS1B/ENSG00000185046.14 0.533 CRCP/ENSG00000241258.2 0.525 C12ORF10/ENSG00000139637.9 0.519 ADAM28/ENSG00000042980.8 0.508 RP11-490K7.4/ENSG00000229447.2 0.506 TMSB15A/ENSG00000158164.6 0.501 OLFML3/ENSG00000116774.7 0.498 SERPINI1/ENSG00000163536.8 0.494 SLC44A5/ENSG00000137968.12 0.49 RP11-26M5.3/ENSG00000254314.1 0.49 RP1-34H18.1/ENSG00000231121.2 0.476 SMIM4/ENSG00000168273.3 0.474 DUSP6/ENSG00000139318.7 0.472 CLEC4A/ENSG00000111729.8 0.468 SLC2A3/ENSG00000059804.11 0.467 ELMO1/ENSG00000155849.11 0.462 CTD-2290C23.1/ENSG00000224282.3 0.458 ITGB8/ENSG00000105855.4 0.457 RNASEH1P1/ENSG00000265790.1 0.455 INTS9/ENSG00000104299.10 0.452 SLC35F1/ENSG00000196376.6 0.448 USB1/ENSG00000103005.6 0.446 NMD3/ENSG00000169251.8 0.443 CCNJP2/ENSG00000223896.2 0.442 IGDCC4/ENSG00000103742.7 0.441 ZNF271/ENSG00000257267.1 0.439 RP11-90K6.1/ENSG00000239482.1 0.438 RSBN1L-AS1/ENSG00000214293.4 0.436 RBM3/ENSG00000102317.13 0.43 PPM1K/ENSG00000163644.9 0.43 CYB5R1/ENSG00000159348.8 0.429 HOXA1/ENSG00000105991.7 0.429 PPP1R1A/ENSG00000135447.12 0.424 CSRNP3/ENSG00000178662.11 0.422 SFRP1/ENSG00000104332.7 0.42 PCDH9/ENSG00000184226.10 0.419 FAM110B/ENSG00000169122.7 0.416 HNRNPH2/ENSG00000126945.8 0.416 SCGN/ENSG00000079689.9 0.415 NDUFAF4/ENSG00000123545.5 0.412 ATP10D/ENSG00000145246.9 0.411 WIPI1/ENSG00000070540.8 0.41 SULF2/ENSG00000196562.10 0.409 CTNNAL1/ENSG00000119326.10 0.409 CCDC150/ENSG00000144395.13 0.404 APOC3/ENSG00000110245.7 0.403 THBS3/ENSG00000169231.8 0.401 HSPA12A/ENSG00000165868.8 0.395 CRTAM/ENSG00000109943.4 0.393 ARX/ENSG00000004848.6 0.393 IMMP1L/ENSG00000148950.5 0.392 ZSCAN9/ENSG00000137185.7 0.39 VASP/ENSG00000125753.9 0.389 ZNF532/ENSG00000074657.9 0.387 FCHSD2/ENSG00000137478.10 0.376 TSHR/ENSG00000165409.11 0.371 IDS/ENSG00000010404.13 0.362 S100Z/ENSG00000171643.9 0.354 DICER1-AS1/ENSG00000235706.3 0.354 RNU4ATAC/ENSG00000264229.1 0.353 NRP1/ENSG00000099250.12 0.349 PPP1R11/ENSG00000204619.3 0.344 EML4/ENSG00000143924.14 0.342 RP11-101E14.2/ENSG00000237767.1 0.34 RP3-508I15.9/ENSG00000228274.2 0.338 AMIGO2/ENSG00000139211.5 0.337 RP11-631M6.2/ENSG00000250461.1 0.336 FREM1/ENSG00000164946.15 0.334 RNF19A/ENSG00000034677.7 0.333 LYRM1/ENSG00000102897.5 0.328 MAFB/ENSG00000204103.2 0.325 AC073283.4/ENSG00000234690.2 0.322 C18ORF8/ENSG00000141452.5 0.321 MED6/ENSG00000133997.7 0.321 DBC1/ENSG00000078725.8 0.32 NIPSNAP1/ENSG00000184117.7 0.318 CTC-273B12.8/ENSG00000269751.1 0.315 GDI1/ENSG00000203879.7 0.315 NHEJ1/ENSG00000187736.8 0.311 NR6A1/ENSG00000148200.12 0.311 RP11-1143G9.2/ENSG00000257818.1 0.309 CRNDE/ENSG00000245694.4 0.306 CDHR3/ENSG00000128536.11 0.305 CRHR1-IT1/ENSG00000204650.9 0.303 CCDC162P/ENSG00000203799.6 0.303 RP11-627G18.3/ENSG00000266010.1 0.298 TP53INP1/ENSG00000164938.9 0.29 SCML2/ENSG00000102098.13 0.289 RP3-399L15.3/ENSG00000228624.2 0.287 SNCA/ENSG00000145335.11 0.286 GFRA3/ENSG00000146013.6 0.285 CTD-2369P2.2/ENSG00000175898.4 0.283 EMP2/ENSG00000213853.5 0.276 DCTN6/ENSG00000104671.3 0.276 NPY/ENSG00000122585.3 0.271 RP3-471C18.2/ENSG00000237404.1 0.27 NAPA/ENSG00000105402.3 0.267 AC073871.2/ENSG00000182648.7 0.267 LYSMD1/ENSG00000163155.7 0.267 CTD-2291D10.4/ENSG00000267886.1 0.266 SHOC2/ENSG00000108061.7 0.266 PSME4/ENSG00000068878.10 0.264 LINC00616/ENSG00000248307.1 0.264 FOXP1/ENSG00000114861.14 0.262 RP11-363E7.4/ENSG00000260912.1 0.261 F10/ENSG00000126218.7 0.26 NR2F1/ENSG00000175745.7 0.26 RP4-633I8.4/ENSG00000228423.1 0.259 TMEM11/ENSG00000178307.5 0.256 MBOAT4/ENSG00000177669.3 0.254 FAM49B/ENSG00000153310.14 0.253 SERPING1/ENSG00000149131.11 Overrepresented GO terms in EP #28: Term Pvalue trigeminal nerve development 0.001138891 neuron projection guidance 0.001868243 central nervous system development 0.002147904 motor neuron axon guidance 0.002232501 hormone-mediated apoptotic signaling pathway 0.002531547 gonadotrophin-releasing hormone neuronal migration to the hypothalamus 0.002531547 hypothalamus gonadotrophin-releasing hormone neuron differentiation 0.002531547 facioacoustic ganglion development 0.002531547 cellular response to fibroblast growth factor stimulus 0.003896874 localization of cell 0.00516777 taxis 0.006458348 epithelial cell fate commitment 0.007133906 axon regeneration 0.007374372 negative regulation of very-low-density lipoprotein particle remodeling 0.007552691 trunk segmentation 0.007552691 ventral trunk neural crest cell migration 0.007552691 nerve development 0.007750659 central nervous system neuron development 0.007750659 neuron projection development 0.008345762 high-density lipoprotein particle remodeling 0.008862634 diencephalon development 0.010266798 "blood coagulation, intrinsic pathway " 0.010840913 reverse cholesterol transport 0.010840913 negative chemotaxis 0.011287132 substrate-dependent cerebral cortex tangential migration 0.015021997 hypothalamus cell migration 0.015021997 sensory system development 0.015021997 trigeminal ganglion development 0.015021997 dehydroascorbic acid transport 0.015021997 sympathetic neuron projection extension 0.015021997 sympathetic neuron projection guidance 0.015021997 neural crest cell migration involved in autonomic nervous system development 0.015021997 regulation of macrophage colony-stimulating factor production 0.015021997 neuron differentiation 0.016173859 cell migration 0.020421246 retinal ganglion cell axon guidance 0.021532692 neurogenesis 0.022785968 trigeminal nerve structural organization 0.024898544 regulation of Cdc42 protein signal transduction 0.024898544 axonogenesis involved in innervation 0.024898544 dichotomous subdivision of terminal units involved in salivary gland branching 0.024898544 axonal fasciculation 0.024967583 exploration behavior 0.024967583 sympathetic nervous system development 0.024967583 limbic system development 0.025510196 cranial nerve morphogenesis 0.028732802 protein-lipid complex remodeling 0.028732802 regionalization 0.032193957 cell adhesion 0.036144776 pallium development 0.036630775 digestion 0.041010708 head development 0.042218494 hormone-mediated signaling pathway 0.044237085 axonogenesis 0.045477915 --------------------------------------------- "EP #29: 176 cells, 333 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0.0147058823529412, stage3_: 0.0142857142857143, St4_3_: 0, stage4: 0.0571428571428571, St5_3_: 0.506849315068493, stage5_: 0.3125, stage6.2_: 0.475609756097561, stage6.7_: 0.657894736842105, stage6.14_: 0.358208955223881, " Top Genes: 2.86 S100A10/ENSG00000197747.4 2.766 GSTA1/ENSG00000243955.1 2.55 IFITM3/ENSG00000142089.11 2.494 FGB/ENSG00000171564.7 2.492 ANXA2/ENSG00000182718.11 2.156 MGST1/ENSG00000008394.7 2.116 PDLIM1/ENSG00000107438.4 2.098 FN1/ENSG00000115414.14 1.833 AC132217.4/ENSG00000240801.1 1.798 TNFSF10/ENSG00000121858.6 1.665 ANXA4/ENSG00000196975.9 1.589 S100A11/ENSG00000163191.5 1.581 GPX2/ENSG00000176153.10 1.573 FOS/ENSG00000170345.5 1.551 RARRES2/ENSG00000106538.5 1.542 APOC1/ENSG00000130208.5 1.523 SPINK1/ENSG00000164266.6 1.513 NQO1/ENSG00000181019.8 1.497 TMEM14A/ENSG00000096092.5 1.469 CD9/ENSG00000010278.7 1.465 ID2/ENSG00000115738.5 1.403 ABRACL/ENSG00000146386.7 1.354 S100A6/ENSG00000197956.5 1.337 TFRC/ENSG00000072274.8 1.319 MRPL16/ENSG00000166902.4 1.311 CKB/ENSG00000166165.8 1.301 WFDC2/ENSG00000101443.13 1.273 PSME1/ENSG00000092010.10 1.27 TSPAN7/ENSG00000156298.8 1.263 IFITM1/ENSG00000185885.11 1.231 MTUS1/ENSG00000129422.9 1.23 AGR2/ENSG00000106541.7 1.199 GSTA2/ENSG00000244067.1 1.198 SLC25A37/ENSG00000147454.9 1.183 IGF2/ENSG00000167244.12 1.171 TM4SF4/ENSG00000169903.6 1.169 RP11-161H23.5/ENSG00000258232.2 1.154 S100A16/ENSG00000188643.6 1.145 TCN1/ENSG00000134827.3 1.142 LDHB/ENSG00000111716.8 1.12 LYPD6B/ENSG00000150556.12 1.113 SULT1E1/ENSG00000109193.6 1.04 ZFP36L2/ENSG00000152518.5 1.032 GOLM1/ENSG00000135052.12 1 SAT1/ENSG00000130066.12 0.998 NTS/ENSG00000133636.6 0.962 SUCLG1/ENSG00000163541.7 0.96 UPK1B/ENSG00000114638.3 0.953 TSPAN3/ENSG00000140391.10 0.938 EGR1/ENSG00000120738.7 0.93 UGDH/ENSG00000109814.7 0.928 CTSC/ENSG00000109861.11 0.926 ELF3/ENSG00000163435.11 0.926 CTSE/ENSG00000196188.6 0.912 LGALS3BP/ENSG00000108679.7 0.899 FGG/ENSG00000171557.12 0.895 KRT8/ENSG00000170421.7 0.893 VMP1/ENSG00000062716.5 0.875 AC107016.1/ENSG00000225410.1 0.875 AGR3/ENSG00000173467.4 0.867 GIF/ENSG00000134812.3 0.859 RP11-1143G9.4/ENSG00000257764.2 0.851 DANCR/ENSG00000226950.2 0.847 KRT18/ENSG00000111057.6 0.831 RPL22L1/ENSG00000163584.13 0.831 FABP5/ENSG00000164687.6 0.812 ETHE1/ENSG00000105755.3 0.808 SERPINB6/ENSG00000124570.13 0.799 ELOVL6/ENSG00000170522.5 0.799 TSPAN6/ENSG00000000003.10 0.796 CTSH/ENSG00000103811.11 0.792 CAMK2D/ENSG00000145349.12 0.788 RAMP1/ENSG00000132329.6 0.784 LAMA1/ENSG00000101680.9 0.772 LGALS3/ENSG00000131981.11 0.759 ARHGAP26/ENSG00000145819.11 0.758 RNASE1/ENSG00000129538.9 0.758 SOX4/ENSG00000124766.4 0.756 KLF5/ENSG00000102554.9 0.735 RHBDD2/ENSG00000005486.12 0.732 DECR1/ENSG00000104325.2 0.727 NOP16/ENSG00000048162.15 0.722 CA4/ENSG00000167434.5 0.718 TBL1XR1/ENSG00000177565.11 0.718 BLVRB/ENSG00000090013.5 0.717 TMEM176A/ENSG00000002933.3 0.716 NEDD4L/ENSG00000049759.12 0.712 EEF1D/ENSG00000104529.13 0.708 PABPC1/ENSG00000070756.9 0.708 TXNRD1/ENSG00000198431.11 0.706 NFE2L2/ENSG00000116044.11 0.702 RBP1/ENSG00000114115.5 0.691 C17ORF76-AS1/ENSG00000175061.12 0.69 ASPH/ENSG00000198363.11 0.688 DAZAP2/ENSG00000183283.10 0.686 DCTPP1/ENSG00000179958.4 0.684 LAMC1/ENSG00000135862.5 0.681 CALB1/ENSG00000104327.3 0.676 TMSB4X/ENSG00000205542.6 0.675 PDLIM5/ENSG00000163110.10 0.674 RPS2/ENSG00000140988.11 0.669 NEAT1/ENSG00000245532.3 0.668 RP4-781K5.2/ENSG00000228830.1 0.654 LAMB1/ENSG00000091136.9 0.646 RPS27L/ENSG00000185088.8 0.642 SULT1C2/ENSG00000198203.5 0.64 HMGCS2/ENSG00000134240.7 0.638 EIF6/ENSG00000242372.2 0.631 CRIP1/ENSG00000213145.5 0.623 ANXA10/ENSG00000109511.6 0.619 ATP1B1/ENSG00000143153.7 0.619 AIG1/ENSG00000146416.12 0.615 ADD3/ENSG00000148700.9 0.613 PLD1/ENSG00000075651.11 0.607 CNN3/ENSG00000117519.11 0.604 MRPS25/ENSG00000131368.3 0.598 TMSB15A/ENSG00000158164.6 0.596 SNHG3/ENSG00000242125.1 0.593 HERPUD1/ENSG00000051108.10 0.587 KLF13/ENSG00000169926.5 0.586 FILIP1L/ENSG00000168386.14 0.583 TSPAN13/ENSG00000106537.7 0.582 FBL/ENSG00000105202.3 0.573 VIL1/ENSG00000127831.6 0.558 ERGIC3/ENSG00000125991.14 0.556 AMBP/ENSG00000106927.7 0.556 MLLT3/ENSG00000171843.11 0.553 IRF2BP2/ENSG00000168264.6 0.553 PSMB10/ENSG00000205220.7 0.546 NTF3/ENSG00000185652.6 0.545 IMPDH2/ENSG00000178035.7 0.544 TUBB4B/ENSG00000188229.5 0.544 PTPRF/ENSG00000142949.12 0.541 MCM7/ENSG00000166508.13 0.532 RPL18AP3/ENSG00000213442.4 0.532 PPA1/ENSG00000180817.6 0.522 ABCG2/ENSG00000118777.6 0.521 NDUFV1/ENSG00000167792.7 0.521 MRPS35/ENSG00000061794.8 0.518 RP11-770J1.5/ENSG00000254873.1 0.515 TES/ENSG00000135269.13 0.512 ATF7IP2/ENSG00000166669.9 0.508 CPM/ENSG00000135678.7 0.507 RAB31/ENSG00000168461.8 0.507 FMNL2/ENSG00000157827.15 0.506 CKS1B/ENSG00000173207.8 0.504 ACY1/ENSG00000243989.3 0.503 PRDX4/ENSG00000123131.8 0.502 WEE1/ENSG00000166483.6 0.501 PTRH2/ENSG00000141378.13 0.498 SMIM14/ENSG00000163683.6 0.498 TAGLN2/ENSG00000158710.10 0.498 GGCT/ENSG00000006625.13 0.496 "ARHGAP8,PRR5-ARHGAP8/ENSG00000241484.5" 0.495 AHI1/ENSG00000135541.16 0.495 LYZ/ENSG00000090382.2 0.493 TACC1/ENSG00000147526.15 0.491 TKT/ENSG00000163931.11 0.49 PRKAA1/ENSG00000132356.7 0.489 PDHA1/ENSG00000131828.9 0.488 VDAC1/ENSG00000213585.6 0.487 PLA2G16/ENSG00000176485.6 0.486 SLC4A7/ENSG00000033867.12 0.482 EIF2S3/ENSG00000130741.5 0.479 UGCG/ENSG00000148154.5 0.479 MRPS12/ENSG00000128626.7 0.476 EHBP1/ENSG00000115504.10 0.474 NDUFAF2/ENSG00000164182.6 0.473 PKP2/ENSG00000057294.9 0.473 HEBP1/ENSG00000013583.4 0.47 COL2A1/ENSG00000139219.13 0.467 ANXA3/ENSG00000138772.8 0.464 ALDH1A1/ENSG00000165092.8 0.46 GLUD1/ENSG00000148672.7 0.457 DUSP1/ENSG00000120129.5 0.457 MPZL2/ENSG00000149573.3 0.455 B2M/ENSG00000166710.12 0.449 SHH/ENSG00000164690.3 0.446 SLC40A1/ENSG00000138449.6 0.445 MAT2B/ENSG00000038274.11 0.445 HEXB/ENSG00000049860.9 0.444 APOE/ENSG00000130203.5 0.442 EPCAM/ENSG00000119888.6 0.438 CDK14/ENSG00000058091.12 0.438 MTRNR2L8/ENSG00000255823.1 0.437 NDUFAF4/ENSG00000123545.5 0.436 NME1/ENSG00000239672.3 0.433 SMC3/ENSG00000108055.9 0.432 MYC/ENSG00000136997.10 0.43 RP11-122C9.1/ENSG00000137970.7 0.429 HES1/ENSG00000114315.3 0.428 EFNA1/ENSG00000169242.7 0.428 SGK1/ENSG00000118515.7 0.426 TMEM123/ENSG00000152558.10 0.423 TUBA1C/ENSG00000167553.10 0.421 CA2/ENSG00000104267.5 0.42 GCG/ENSG00000115263.10 0.419 SMIM20/ENSG00000250317.4 0.418 STAP2/ENSG00000178078.7 0.416 NME6/ENSG00000172113.4 0.414 COBLL1/ENSG00000082438.11 0.411 COLGALT1/ENSG00000130309.6 0.41 PHGDH/ENSG00000092621.7 0.409 TPD52/ENSG00000076554.11 0.407 SAMM50/ENSG00000100347.10 0.406 APOC1P1/ENSG00000214855.5 0.406 NTRK2/ENSG00000148053.11 0.406 EBNA1BP2/ENSG00000117395.6 0.404 TAPBP/ENSG00000231925.7 0.404 CCNL1/ENSG00000163660.7 0.403 MDK/ENSG00000110492.11 0.401 ADK/ENSG00000156110.9 0.401 CLU/ENSG00000120885.15 0.401 GSTA4/ENSG00000170899.6 0.399 LLGL2/ENSG00000073350.9 0.398 ZFAS1/ENSG00000177410.8 0.396 RP11-466H18.1/ENSG00000244398.1 0.394 LGALS8/ENSG00000116977.14 0.393 NFIB/ENSG00000147862.9 0.393 ZNF124/ENSG00000196418.7 0.392 BOLA3/ENSG00000163170.7 0.39 SP100/ENSG00000067066.12 0.389 RP11-632C17__A.1/ENSG00000230202.1 0.387 C9ORF123/ENSG00000137038.7 0.387 MYO1B/ENSG00000128641.13 0.384 RAB34/ENSG00000109113.13 0.383 USP3/ENSG00000140455.12 0.381 CLDN4/ENSG00000189143.8 0.377 FUT8/ENSG00000033170.12 0.376 TRIM5/ENSG00000132256.14 0.374 MEIS1/ENSG00000143995.14 0.372 ITLN1/ENSG00000179914.4 0.372 PRSS8/ENSG00000052344.11 0.369 TFF1/ENSG00000160182.2 0.368 PRR15L/ENSG00000167183.2 0.368 RHPN2/ENSG00000131941.3 0.363 GTF2E2/ENSG00000197265.4 0.36 PGAP2/ENSG00000148985.15 0.359 CTB-63M22.1/ENSG00000229119.3 0.358 SH3RF1/ENSG00000154447.10 0.358 B4GALT4/ENSG00000121578.8 0.357 MEIS2/ENSG00000134138.14 0.357 NIT2/ENSG00000114021.6 0.356 PLCXD2/ENSG00000240891.2 0.355 PDIA4/ENSG00000155660.6 0.355 WDR3/ENSG00000065183.10 0.354 SLC4A4/ENSG00000080493.9 0.351 RRBP1/ENSG00000125844.10 0.348 EPHX2/ENSG00000120915.9 0.347 GDF15/ENSG00000130513.5 0.345 SNHG5/ENSG00000203875.5 0.344 MOV10/ENSG00000155363.14 0.343 YAP1/ENSG00000137693.9 0.34 ACOT9/ENSG00000123130.12 0.34 RP11-627G18.3/ENSG00000266010.1 0.34 ACTR3/ENSG00000115091.7 0.338 FKBP9/ENSG00000122642.6 0.337 BAZ1A/ENSG00000198604.6 0.337 TTC39C/ENSG00000168234.8 0.335 ITGA4/ENSG00000115232.9 0.335 MTHFD2/ENSG00000065911.7 0.335 ETFB/ENSG00000105379.5 0.334 BZW2/ENSG00000136261.10 0.332 MRRF/ENSG00000148187.12 0.331 SMAGP/ENSG00000170545.12 0.33 NUDT19/ENSG00000213965.3 0.33 APOBEC3B/ENSG00000179750.11 0.328 UGT8/ENSG00000174607.6 0.327 ROBO1/ENSG00000169855.15 0.324 LETMD1/ENSG00000050426.10 0.323 POLE3/ENSG00000148229.8 0.321 ATP5G1/ENSG00000159199.8 0.32 GSTM3/ENSG00000134202.6 0.317 ALG8/ENSG00000159063.8 0.316 IFITM2/ENSG00000185201.12 0.313 TMX2/ENSG00000213593.5 0.31 PGM2/ENSG00000169299.9 0.307 CCND2/ENSG00000118971.3 0.307 CKS2/ENSG00000123975.4 0.307 KRTCAP3/ENSG00000157992.8 0.306 DYNLT3/ENSG00000165169.6 0.305 WBSCR22/ENSG00000071462.7 0.302 P4HA2/ENSG00000072682.13 0.3 ERBB2IP/ENSG00000112851.10 0.298 C19ORF77/ENSG00000095932.5 0.298 VAMP8/ENSG00000118640.6 0.298 SLC44A4/ENSG00000204385.6 0.294 DUSP5/ENSG00000138166.5 0.293 TBC1D23/ENSG00000036054.8 0.291 RP11-572P18.1/ENSG00000220842.5 0.289 VSIG1/ENSG00000101842.9 0.289 FAR1/ENSG00000197601.8 0.289 RP11-6N17.6/ENSG00000264019.1 0.288 DNAJB11/ENSG00000090520.6 0.288 C1ORF116/ENSG00000182795.12 0.287 HADH/ENSG00000138796.11 0.287 FGA/ENSG00000171560.10 0.285 HDHD3/ENSG00000119431.5 0.285 GK/ENSG00000198814.8 0.284 TMEM144/ENSG00000164124.6 0.284 SNHG8/ENSG00000269893.1 0.283 NOLC1/ENSG00000166197.12 0.282 ZNF880/ENSG00000221923.4 0.281 ATP13A3/ENSG00000133657.10 0.28 PLGRKT/ENSG00000107020.5 0.279 REC8/ENSG00000100918.8 0.279 HMGA1/ENSG00000137309.15 0.278 LGMN/ENSG00000100600.10 0.277 LDLR/ENSG00000130164.7 0.275 DUSP6/ENSG00000139318.7 0.275 ACAA1/ENSG00000060971.12 0.271 SERPINB1/ENSG00000021355.8 0.271 FAM211A/ENSG00000181350.7 0.27 RASSF4/ENSG00000107551.15 0.268 MAP3K8/ENSG00000107968.5 0.266 TAX1BP3/ENSG00000213977.3 0.266 CLIC1/ENSG00000213719.4 0.264 TARBP1/ENSG00000059588.5 0.263 LSM10/ENSG00000181817.5 0.263 GSTO1/ENSG00000148834.8 0.26 TMPRSS4/ENSG00000137648.12 0.259 INS/ENSG00000254647.2 0.258 TMEM176B/ENSG00000106565.13 0.258 GALE/ENSG00000117308.10 0.256 GPRC5C/ENSG00000170412.12 0.255 AK2/ENSG00000004455.12 0.255 CHCHD10/ENSG00000250479.4 0.254 EMG1/ENSG00000126749.8 0.253 ENOSF1/ENSG00000132199.13 0.252 ARRDC3/ENSG00000113369.4 0.251 EBF4/ENSG00000088881.15 0.251 FARSB/ENSG00000116120.8 0.25 GUCD1/ENSG00000138867.12 Overrepresented GO terms in EP #29: Term Pvalue negative regulation of cell death 3.47E-05 glutathione metabolic process 4.03E-05 glutathione derivative biosynthetic process 6.08E-05 negative regulation of apoptotic process 7.92E-05 cellular amide metabolic process 9.43E-05 detoxification 0.000253098 negative regulation of hemopoiesis 0.000269269 tissue development 0.00048725 substrate adhesion-dependent cell spreading 0.000863809 cellular oxidant detoxification 0.000956755 platelet degranulation 0.001257094 positive regulation of cellular protein metabolic process 0.001377383 cell-cell adhesion 0.001479845 small molecule metabolic process 0.001684759 lipid catabolic process 0.00210016 negative regulation of stem cell differentiation 0.002306018 regulation of programmed cell death 0.002647784 biological adhesion 0.003053823 organonitrogen compound metabolic process 0.004765607 negative regulation of viral entry into host cell 0.010258245 plasminogen activation 0.012986082 glucosylceramide biosynthetic process 0.013878105 endoderm formation 0.01519668 response to metal ion 0.016640229 positive regulation of macromolecule metabolic process 0.016812445 ferrous iron transport 0.02085395 regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.020899834 epithelial cell differentiation 0.021356721 cellular response to xenobiotic stimulus 0.021722834 regulation of apoptotic signaling pathway 0.022361107 purine nucleoside triphosphate biosynthetic process 0.023129776 negative regulation of extrinsic apoptotic signaling pathway 0.023279318 receptor internalization 0.026154592 single-organism cellular process 0.026560572 organonitrogen compound biosynthetic process 0.027067175 immune system process 0.027798698 cellular homeostasis 0.028896909 limb bud formation 0.029358809 cell proliferation involved in metanephros development 0.029358809 nucleoside triphosphate metabolic process 0.036407458 GTP biosynthetic process 0.039782807 positive regulation of heterotypic cell-cell adhesion 0.039782807 oxidation-reduction process 0.040281559 single-organism carbohydrate catabolic process 0.040828959 regulation of phosphatidylcholine catabolic process 0.041092093 positive regulation of peptide hormone secretion 0.044208503 developmental process 0.045327714 establishment of protein localization to plasma membrane 0.047876791 fibrinolysis 0.048171883 nucleobase-containing small molecule metabolic process 0.049495703 --------------------------------------------- "EP #30: 17 cells, 107 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0, stage5_: 0, stage6.2_: 0.0121951219512195, stage6.7_: 0.0789473684210526, stage6.14_: 0.149253731343284, " Top Genes: 3.37 CXCL14/ENSG00000145824.8 2.409 AGR2/ENSG00000106541.7 1.941 FABP1/ENSG00000163586.5 1.866 AGR3/ENSG00000173467.4 1.773 FATE1/ENSG00000147378.7 1.559 NEFL/ENSG00000104725.9 1.539 PRAC/ENSG00000159182.3 1.358 CSRP2/ENSG00000175183.5 1.285 TAC1/ENSG00000006128.7 1.177 TWIST1/ENSG00000122691.8 1.148 AC123023.1/ENSG00000236452.1 1.061 ADD3/ENSG00000148700.9 1.056 LZIC/ENSG00000162441.7 0.987 MLN/ENSG00000096395.6 0.845 LIMS1/ENSG00000169756.12 0.841 HDX/ENSG00000165259.8 0.788 ACBD5/ENSG00000107897.14 0.76 LRRN1/ENSG00000175928.5 0.704 MUCL1/ENSG00000172551.6 0.693 SLC2A2/ENSG00000163581.9 0.69 CTNNBIP1/ENSG00000178585.10 0.681 ANKRD13C/ENSG00000118454.8 0.668 GRIA3/ENSG00000125675.13 0.664 NMD3/ENSG00000169251.8 0.655 C12ORF29/ENSG00000133641.13 0.633 NEFM/ENSG00000104722.9 0.625 ITGA1/ENSG00000213949.3 0.588 COPS7A/ENSG00000111652.5 0.569 TSPAN13/ENSG00000106537.7 0.568 DYNLT3/ENSG00000165169.6 0.558 AOAH/ENSG00000136250.7 0.556 RARRES1/ENSG00000118849.5 0.553 HABP2/ENSG00000148702.10 0.552 MCEE/ENSG00000124370.6 0.544 DUS4L/ENSG00000105865.6 0.529 KRT19/ENSG00000171345.9 0.527 ELMO1/ENSG00000155849.11 0.52 UGT2B7/ENSG00000171234.9 0.518 POU6F2-AS1/ENSG00000224122.1 0.518 DNER/ENSG00000187957.7 0.515 CBLN4/ENSG00000054803.3 0.508 AC010980.2/ENSG00000237732.5 0.496 NENF/ENSG00000117691.5 0.496 GBA3/ENSG00000269541.1 0.472 RP11-413E6.1/ENSG00000243422.1 0.469 NR1H4/ENSG00000012504.9 0.467 ACPP/ENSG00000014257.11 0.461 AC011306.2/ENSG00000226702.1 0.46 TRAK2/ENSG00000115993.7 0.458 FHL1/ENSG00000022267.12 0.456 P2RX6P/ENSG00000206145.4 0.451 GKN2/ENSG00000183607.5 0.443 RP11-690J15.1/ENSG00000258312.1 0.443 PMP22/ENSG00000109099.9 0.442 CNTN1/ENSG00000018236.10 0.425 ME3/ENSG00000151376.12 0.403 MAPK1/ENSG00000100030.10 0.402 SGMS1/ENSG00000198964.7 0.395 ACY1/ENSG00000243989.3 0.386 LINC00470/ENSG00000132204.9 0.385 LXN/ENSG00000079257.3 0.385 RP11-379K17.12/ENSG00000268220.1 0.384 LHFP/ENSG00000183722.7 0.381 RP11-254I22.3/ENSG00000249746.1 0.38 EPHA5/ENSG00000145242.9 0.377 ACTA1/ENSG00000143632.10 0.376 RP1-309F20.4/ENSG00000270951.1 0.356 GATS/ENSG00000239521.2 0.351 COLQ/ENSG00000206561.8 0.35 RP11-643G5.6/ENSG00000255429.1 0.343 RGL1/ENSG00000143344.10 0.34 C9ORF135/ENSG00000204711.4 0.337 NRP2/ENSG00000118257.12 0.334 FAM89A/ENSG00000182118.5 0.334 RP11-182I10.2/ENSG00000233877.2 0.333 EYS/ENSG00000188107.9 0.321 SALL2/ENSG00000165821.7 0.319 IMP4/ENSG00000136718.5 0.317 CALB1/ENSG00000104327.3 0.317 SRGAP3-AS2/ENSG00000228723.2 0.312 AK7/ENSG00000140057.4 0.303 RP11-498E2.8/ENSG00000270102.1 0.302 CTD-2201E18.3/ENSG00000177738.3 0.299 COPG1/ENSG00000181789.10 0.298 CDR1/ENSG00000184258.5 0.297 VNN3/ENSG00000093134.9 0.295 RP11-121M22.1/ENSG00000175773.8 0.294 GALNT13/ENSG00000144278.10 0.292 SORL1/ENSG00000137642.8 0.291 CABYR/ENSG00000154040.16 0.29 MZT1/ENSG00000204899.5 0.288 RP11-565N2.1/ENSG00000261453.1 0.286 CTB-85P21.2/ENSG00000259787.1 0.286 BBOX1/ENSG00000129151.4 0.284 APOA2/ENSG00000158874.6 0.284 RP11-98D18.2/ENSG00000232937.1 0.279 REPS2/ENSG00000169891.13 0.275 STK32A/ENSG00000169302.10 0.274 MMACHC/ENSG00000132763.10 0.271 SLC9B2/ENSG00000164038.10 0.269 S100A14/ENSG00000189334.4 0.269 DLG3-AS1/ENSG00000231651.1 0.268 NRG4/ENSG00000169752.12 0.264 PDE1C/ENSG00000154678.12 0.264 PJA1/ENSG00000181191.11 0.258 FAM110A/ENSG00000125898.7 0.256 APBB2/ENSG00000163697.12 Overrepresented GO terms in EP #30: Term Pvalue cardiac neural crest cell development involved in heart development 0.024886081 ERBB signaling pathway 0.027077888 sensory perception of pain 0.029386022 positive regulation of fatty acid beta-oxidation 0.031891724 outer ear morphogenesis 0.031891724 --------------------------------------------- "EP #31: 628 cells, 507 genes" "Fraction of cells from each time pt- hesc_: 1, stage1_: 1, stage2_: 1, stage3_: 1, St4_3_: 1, stage4: 0.928571428571429, St5_3_: 0.945205479452055, stage5_: 0.75, stage6.2_: 0.560975609756098, stage6.7_: 0.552631578947368, stage6.14_: 0.253731343283582, " Top Genes: 2.34 MDK/ENSG00000110492.11 2.313 NREP/ENSG00000134986.9 2.247 CKB/ENSG00000166165.8 2.043 TUBA1A/ENSG00000167552.9 2.027 MFAP2/ENSG00000117122.9 1.884 LDHB/ENSG00000111716.8 1.723 TSPAN6/ENSG00000000003.10 1.563 GLUL/ENSG00000135821.11 1.542 AASS/ENSG00000008311.10 1.509 ERGIC3/ENSG00000125991.14 1.465 CSRP2/ENSG00000175183.5 1.443 TBL1XR1/ENSG00000177565.11 1.441 TMEM98/ENSG00000006042.7 1.404 CNN3/ENSG00000117519.11 1.396 UCHL1/ENSG00000154277.8 1.338 AC011558.5/ENSG00000267020.1 1.328 EIF2S3/ENSG00000130741.5 1.294 TUBB/ENSG00000196230.8 1.277 TMSB15A/ENSG00000158164.6 1.249 UBE2E3/ENSG00000170035.11 1.246 FN1/ENSG00000115414.14 1.243 TMSB4X/ENSG00000205542.6 1.242 PPA2/ENSG00000138777.15 1.24 MCM7/ENSG00000166508.13 1.214 ENAH/ENSG00000154380.11 1.211 UGDH/ENSG00000109814.7 1.203 HNRPDL/ENSG00000152795.13 1.197 TCF7L2/ENSG00000148737.11 1.171 SOX4/ENSG00000124766.4 1.133 SOX11/ENSG00000176887.5 1.107 MYH10/ENSG00000133026.8 1.104 CBX5/ENSG00000094916.9 1.095 AL358781.1/ENSG00000176868.1 1.083 SFPQ/ENSG00000116560.6 1.08 SRSF7/ENSG00000115875.14 1.077 NASP/ENSG00000132780.12 1.054 HELLS/ENSG00000119969.10 1.051 CTNNB1/ENSG00000168036.12 1.045 USP22/ENSG00000124422.7 1.035 MAGED2/ENSG00000102316.11 1.032 TFDP2/ENSG00000114126.13 1.028 C10ORF82/ENSG00000165863.12 1.026 PTBP2/ENSG00000117569.13 0.993 SET/ENSG00000119335.12 0.989 TPM1/ENSG00000140416.15 0.978 CXADR/ENSG00000154639.14 0.971 PCMTD2/ENSG00000203880.6 0.965 QKI/ENSG00000112531.12 0.955 ZNF286A/ENSG00000187607.11 0.945 TP53/ENSG00000141510.11 0.945 VEZT/ENSG00000028203.13 0.945 NONO/ENSG00000147140.10 0.932 ACVR2A/ENSG00000121989.10 0.925 NR6A1/ENSG00000148200.12 0.923 PAFAH1B3/ENSG00000079462.3 0.92 ILF3/ENSG00000129351.13 0.918 SERPINB6/ENSG00000124570.13 0.918 EEF1D/ENSG00000104529.13 0.916 DCP2/ENSG00000172795.11 0.911 SLC35F2/ENSG00000110660.10 0.907 CCDC14/ENSG00000175455.10 0.906 RAP2B/ENSG00000181467.2 0.895 IGF1R/ENSG00000140443.9 0.892 SAR1A/ENSG00000079332.9 0.884 MARCKS/ENSG00000155130.5 0.883 MAD2L2/ENSG00000116670.10 0.875 CSDE1/ENSG00000009307.11 0.867 APLP2/ENSG00000084234.12 0.866 LRRC16A/ENSG00000079691.15 0.865 RABL5/ENSG00000128581.11 0.863 RIMKLB/ENSG00000166532.11 0.858 SLC38A1/ENSG00000111371.11 0.856 FAM60A/ENSG00000139146.9 0.855 C6ORF62/ENSG00000112308.8 0.846 NAP1L1/ENSG00000187109.9 0.844 PAIP2/ENSG00000120727.6 0.842 GSTO1/ENSG00000148834.8 0.837 HNRNPA1/ENSG00000135486.13 0.834 GDI2/ENSG00000057608.11 0.833 TGIF2/ENSG00000118707.4 0.832 RBMX/ENSG00000147274.10 0.832 CNN2/ENSG00000064666.9 0.831 SERPING1/ENSG00000149131.11 0.824 BNIP3L/ENSG00000104765.10 0.819 XRCC5/ENSG00000079246.11 0.815 PTCD3/ENSG00000132300.14 0.813 RBM8A/ENSG00000131795.7 0.806 IVNS1ABP/ENSG00000116679.11 0.787 HMGB1/ENSG00000189403.10 0.782 CALD1/ENSG00000122786.15 0.778 RTN3/ENSG00000133318.9 0.766 PDLIM5/ENSG00000163110.10 0.764 TSPAN3/ENSG00000140391.10 0.762 TMEM123/ENSG00000152558.10 0.759 FGFR1/ENSG00000077782.15 0.749 ZNF714/ENSG00000160352.11 0.738 MGEA5/ENSG00000198408.9 0.738 OFD1/ENSG00000046651.10 0.737 RBM25/ENSG00000119707.9 0.734 RNF34/ENSG00000170633.12 0.725 CAPZA1/ENSG00000116489.8 0.723 ZNF253/ENSG00000256771.2 0.723 RPAIN/ENSG00000129197.10 0.722 CBX1/ENSG00000108468.10 0.719 PSAP/ENSG00000197746.9 0.717 CTC-359D24.3/ENSG00000242615.1 0.717 WBP5/ENSG00000185222.7 0.714 EEF1A1P5/ENSG00000196205.7 0.713 CTB-43P18.1/ENSG00000249758.1 0.712 BRD7/ENSG00000166164.11 0.711 DMTF1/ENSG00000135164.14 0.708 SNRPE/ENSG00000182004.8 0.706 AL590762.1/ENSG00000255591.1 0.704 RP5-1085F17.3/ENSG00000260257.1 0.698 ECHDC1/ENSG00000093144.14 0.693 SEPP1/ENSG00000250722.1 0.693 SLC38A2/ENSG00000134294.9 0.69 PON2/ENSG00000105854.8 0.69 THOC1/ENSG00000079134.7 0.689 SALL4/ENSG00000101115.8 0.685 PAN3/ENSG00000152520.9 0.683 TPGS2/ENSG00000134779.10 0.682 MATR3/ENSG00000015479.13 0.677 MARCH6/ENSG00000145495.9 0.677 HP1BP3/ENSG00000127483.13 0.674 ZNF124/ENSG00000196418.7 0.674 DCAF13/ENSG00000164934.9 0.674 PABPN1/ENSG00000100836.6 0.672 TGIF1/ENSG00000177426.15 0.67 CALU/ENSG00000128595.12 0.667 ORMDL1/ENSG00000128699.9 0.667 CCDC23/ENSG00000177868.7 0.661 SEPW1/ENSG00000178980.10 0.651 NUP107/ENSG00000111581.5 0.65 DEK/ENSG00000124795.10 0.649 NUDT4/ENSG00000173598.9 0.649 ANKRD40/ENSG00000154945.6 0.648 RANBP17/ENSG00000204764.7 0.645 TSPYL1/ENSG00000189241.6 0.64 RHOC/ENSG00000155366.11 0.635 PPIL3/ENSG00000240344.4 0.632 SGPL1/ENSG00000166224.12 0.628 RAI14/ENSG00000039560.9 0.627 TRA2A/ENSG00000164548.6 0.626 LEPROTL1/ENSG00000104660.13 0.621 ILF2/ENSG00000143621.12 0.618 MARCKSL1/ENSG00000175130.6 0.615 NME6/ENSG00000172113.4 0.614 SNRNP200/ENSG00000144028.10 0.613 EIF4EBP2/ENSG00000148730.6 0.61 ALDH6A1/ENSG00000119711.8 0.608 ZNF43/ENSG00000198521.7 0.604 FAM221A/ENSG00000188732.6 0.599 YWHAZ/ENSG00000164924.13 0.599 ENY2/ENSG00000120533.8 0.598 ZNF638/ENSG00000075292.13 0.597 C1ORF198/ENSG00000119280.12 0.597 EWSR1/ENSG00000182944.13 0.596 SRSF10/ENSG00000188529.10 0.594 GSTP1/ENSG00000084207.11 0.593 SMARCA1/ENSG00000102038.10 0.593 ARID2/ENSG00000189079.11 0.583 RAB3IP/ENSG00000127328.17 0.582 JMJD1C/ENSG00000171988.13 0.581 PARD6B/ENSG00000124171.4 0.579 ACOT13/ENSG00000112304.5 0.573 LAPTM4B/ENSG00000104341.12 0.573 USP11/ENSG00000102226.4 0.572 CTD-2369P2.2/ENSG00000175898.4 0.57 POGLUT1/ENSG00000163389.6 0.57 AKAP13/ENSG00000170776.15 0.569 PPIE/ENSG00000084072.12 0.566 FANCL/ENSG00000115392.7 0.564 F11R/ENSG00000158769.12 0.56 SUPT16H/ENSG00000092201.5 0.558 SH3BGRL/ENSG00000131171.8 0.558 PRMT2/ENSG00000160310.12 0.557 DCBLD2/ENSG00000057019.11 0.555 OLA1/ENSG00000138430.11 0.551 KNTC1/ENSG00000184445.7 0.551 PNRC2/ENSG00000189266.7 0.549 ASF1A/ENSG00000111875.6 0.548 MGST1/ENSG00000008394.7 0.547 CFL1/ENSG00000172757.7 0.545 ZNF761/ENSG00000160336.10 0.545 DCP1A/ENSG00000162290.11 0.544 ZNF649/ENSG00000198093.6 0.544 TRIM59/ENSG00000213186.3 0.543 TRO/ENSG00000067445.15 0.541 BNIP2/ENSG00000140299.6 0.539 OGT/ENSG00000147162.9 0.539 ATF7IP/ENSG00000171681.8 0.537 ANP32E/ENSG00000143401.10 0.535 TMEM219/ENSG00000149932.12 0.533 ABRACL/ENSG00000146386.7 0.532 RMND1/ENSG00000155906.12 0.531 H2AFY/ENSG00000113648.12 0.529 ZNF880/ENSG00000221923.4 0.528 KDM6A/ENSG00000147050.10 0.526 PHF6/ENSG00000156531.12 0.52 XRN2/ENSG00000088930.6 0.52 PDIA6/ENSG00000143870.8 0.517 RFXANK/ENSG00000064490.7 0.516 IP6K2/ENSG00000068745.10 0.515 SMARCAD1/ENSG00000163104.13 0.514 PKM/ENSG00000067225.13 0.513 NNAT/ENSG00000053438.7 0.513 TGFBR1/ENSG00000106799.7 0.512 NUP160/ENSG00000030066.9 0.51 PTPN12/ENSG00000127947.11 0.508 RCN2/ENSG00000117906.9 0.505 WTAP/ENSG00000146457.10 0.505 VPS25/ENSG00000131475.2 0.503 ERCC3/ENSG00000163161.8 0.502 SMARCC1/ENSG00000173473.6 0.501 MYL6B/ENSG00000196465.5 0.5 CBX3/ENSG00000122565.14 0.498 SAT1/ENSG00000130066.12 0.496 CREB1/ENSG00000118260.9 0.494 SPATS2/ENSG00000123352.13 0.493 BRE/ENSG00000158019.16 0.491 DCTD/ENSG00000129187.10 0.49 RWDD3/ENSG00000122481.12 0.489 MSH2/ENSG00000095002.8 0.489 "ARHGAP8,PRR5-ARHGAP8/ENSG00000241484.5" 0.488 CLIC4/ENSG00000169504.10 0.487 C22ORF29/ENSG00000215012.4 0.486 LPHN2/ENSG00000117114.15 0.485 HAUS1/ENSG00000152240.8 0.484 DDX39B/ENSG00000198563.9 0.483 TOMM34/ENSG00000025772.7 0.483 CPVL/ENSG00000106066.9 0.482 SALL2/ENSG00000165821.7 0.481 POGZ/ENSG00000143442.17 0.479 GPRC5B/ENSG00000167191.7 0.476 ODF2L/ENSG00000122417.11 0.476 MUM1/ENSG00000160953.10 0.475 RCC2/ENSG00000179051.9 0.474 TLK1/ENSG00000198586.9 0.473 ZNF146/ENSG00000167635.7 0.473 SPG21/ENSG00000090487.6 0.472 BRD8/ENSG00000112983.13 0.47 NXF1/ENSG00000162231.8 0.468 SF3B1/ENSG00000115524.10 0.468 FAM172A/ENSG00000113391.12 0.463 RBFOX2/ENSG00000100320.18 0.462 NOSIP/ENSG00000142546.9 0.462 IGF2BP1/ENSG00000159217.5 0.462 CTNNA1/ENSG00000044115.15 0.459 HNRNPH1/ENSG00000169045.13 0.456 NIPSNAP1/ENSG00000184117.7 0.455 SKIL/ENSG00000136603.9 0.453 PTPRS/ENSG00000105426.10 0.452 CHD1L/ENSG00000131778.13 0.452 BAG4/ENSG00000156735.6 0.451 MTA3/ENSG00000057935.9 0.451 HNRNPC/ENSG00000092199.13 0.45 ZNF561/ENSG00000171469.6 0.448 ZNF677/ENSG00000197928.6 0.442 NUP50/ENSG00000093000.13 0.441 CD200/ENSG00000091972.13 0.44 WDR41/ENSG00000164253.8 0.439 TSPAN14/ENSG00000108219.9 0.438 ITSN1/ENSG00000205726.9 0.438 TMSB10/ENSG00000034510.4 0.437 SNRPN/ENSG00000128739.16 0.437 ESRP1/ENSG00000104413.11 0.436 ZNF83/ENSG00000167766.13 0.43 IQCK/ENSG00000174628.12 0.43 FSTL1/ENSG00000163430.5 0.427 COLGALT1/ENSG00000130309.6 0.427 PTPRK/ENSG00000152894.10 0.426 TMEM243/ENSG00000135185.7 0.424 PRPF3/ENSG00000117360.8 0.424 PXDN/ENSG00000130508.6 0.421 RAB34/ENSG00000109113.13 0.421 DERA/ENSG00000023697.8 0.418 GMPS/ENSG00000163655.10 0.418 HMGN4/ENSG00000182952.4 0.416 PAPOLG/ENSG00000115421.8 0.415 COX15/ENSG00000014919.8 0.415 CYFIP2/ENSG00000055163.14 0.413 OTUB1/ENSG00000167770.7 0.412 ZC4H2/ENSG00000126970.11 0.41 LCLAT1/ENSG00000172954.9 0.41 UNG/ENSG00000076248.6 0.409 HARS/ENSG00000170445.8 0.408 MCM3/ENSG00000112118.12 0.408 MYO1B/ENSG00000128641.13 0.408 HNRNPA0/ENSG00000177733.4 0.407 PTPN13/ENSG00000163629.8 0.406 NARG2/ENSG00000128915.7 0.404 EXTL2/ENSG00000162694.9 0.404 ATXN3/ENSG00000066427.17 0.398 HILPDA/ENSG00000135245.9 0.398 GRHPR/ENSG00000137106.12 0.397 TMEM106C/ENSG00000134291.7 0.395 GTF2E1/ENSG00000153767.5 0.395 TRIM24/ENSG00000122779.12 0.394 EIF5/ENSG00000100664.6 0.393 PRPF38A/ENSG00000134748.11 0.393 MRPS6/ENSG00000243927.1 0.393 ZC3H13/ENSG00000123200.12 0.393 MCRS1/ENSG00000187778.9 0.39 RP11-265N6.1/ENSG00000261684.1 0.39 DERL2/ENSG00000072849.6 0.39 ORC6/ENSG00000091651.4 0.389 FUS/ENSG00000089280.14 0.389 DMAP1/ENSG00000178028.9 0.388 AGO1/ENSG00000092847.6 0.388 SNX7/ENSG00000162627.12 0.386 SYNE2/ENSG00000054654.11 0.386 HMGN5/ENSG00000198157.6 0.386 HMGB2/ENSG00000164104.7 0.384 KIAA1009/ENSG00000135315.7 0.383 ICA1/ENSG00000003147.13 0.383 ABLIM1/ENSG00000099204.14 0.382 FGD4/ENSG00000139132.10 0.381 C20ORF111/ENSG00000132823.6 0.381 BAZ1A/ENSG00000198604.6 0.38 HTATSF1/ENSG00000102241.7 0.377 BRD3/ENSG00000169925.12 0.377 CTNNAL1/ENSG00000119326.10 0.377 C19ORF48/ENSG00000167747.9 0.376 SRGAP2/ENSG00000163486.8 0.374 DDHD1/ENSG00000100523.10 0.374 ARL6IP1/ENSG00000170540.10 0.372 PTGFRN/ENSG00000134247.9 0.372 TAX1BP3/ENSG00000213977.3 0.37 ZC3HC1/ENSG00000091732.11 0.369 KRIT1/ENSG00000001631.10 0.366 BSG/ENSG00000172270.14 0.366 ZNF85/ENSG00000105750.10 0.365 TRIM45/ENSG00000134253.5 0.365 ATAT1/ENSG00000137343.13 0.364 PUM2/ENSG00000055917.11 0.364 PDIA4/ENSG00000155660.6 0.362 RP11-732M18.3/ENSG00000236537.1 0.362 EZH2/ENSG00000106462.6 0.362 RAP2C/ENSG00000123728.5 0.361 CRYZ/ENSG00000116791.9 0.36 "PMF1,PMF1-BGLAP/ENSG00000160783.13" 0.36 SEC22A/ENSG00000121542.7 0.359 SRP72/ENSG00000174780.11 0.358 SLC16A1/ENSG00000155380.7 0.358 NEO1/ENSG00000067141.12 0.357 HNRNPF/ENSG00000169813.12 0.356 DDX52/ENSG00000141141.10 0.356 OXA1L/ENSG00000155463.8 0.353 YTHDC1/ENSG00000083896.8 0.353 SNAP23/ENSG00000092531.5 0.352 CASP2/ENSG00000106144.15 0.352 SDC4/ENSG00000124145.5 0.349 RP11-701H24.4/ENSG00000261069.1 0.348 SCAF11/ENSG00000139218.12 0.348 SDF2/ENSG00000132581.4 0.347 KPNA3/ENSG00000102753.5 0.347 CMTM3/ENSG00000140931.15 0.346 RP11-301L7.1/ENSG00000271051.1 0.346 SMIM19/ENSG00000176209.6 0.345 TEAD2/ENSG00000074219.9 0.342 ATP11C/ENSG00000101974.10 0.342 FBXL5/ENSG00000118564.10 0.341 DLG3/ENSG00000082458.7 0.34 UBLCP1/ENSG00000164332.6 0.339 GPR125/ENSG00000152990.9 0.339 RAF1/ENSG00000132155.7 0.338 POLR3C/ENSG00000186141.4 0.338 FMR1/ENSG00000102081.9 0.338 TMEFF1/ENSG00000241697.3 0.336 RIF1/ENSG00000080345.12 0.336 TXNDC12/ENSG00000117862.6 0.335 CARHSP1/ENSG00000153048.6 0.333 KPNA1/ENSG00000114030.8 0.333 CAPRIN2/ENSG00000110888.13 0.332 ZNF528/ENSG00000167555.9 0.332 C3ORF58/ENSG00000181744.4 0.33 ZFP62/ENSG00000196670.9 0.33 PDE9A/ENSG00000160191.13 0.33 PIGC/ENSG00000135845.4 0.33 CREB3L4/ENSG00000143578.11 0.329 WDR45/ENSG00000196998.10 0.329 PSEN1/ENSG00000080815.14 0.329 SVIL/ENSG00000197321.10 0.329 ADAM17/ENSG00000151694.8 0.328 ELP6/ENSG00000163832.11 0.328 LPAR2/ENSG00000064547.9 0.328 DIS3L/ENSG00000166938.8 0.327 SRSF3/ENSG00000112081.11 0.327 BCL10/ENSG00000142867.8 0.327 UBE2I/ENSG00000103275.14 0.324 FXYD6/ENSG00000137726.11 0.323 KNOP1/ENSG00000103550.9 0.322 ZNF766/ENSG00000196214.6 0.322 ERCC1/ENSG00000012061.11 0.322 CHEK1/ENSG00000149554.8 0.321 ZNF280B/ENSG00000198477.3 0.321 ASNA1/ENSG00000198356.7 0.321 VAT1/ENSG00000108828.11 0.321 LPP/ENSG00000145012.8 0.32 RP11-119F7.5/ENSG00000260400.1 0.32 OPA1/ENSG00000198836.4 0.319 OIP5-AS1/ENSG00000247556.2 0.319 C1ORF106/ENSG00000163362.6 0.319 ZNF577/ENSG00000161551.8 0.318 EIF3L/ENSG00000100129.12 0.318 UBE2L6/ENSG00000156587.11 0.318 C7ORF55-LUC7L2/ENSG00000146963.12 0.316 FAM126A/ENSG00000122591.7 0.316 NUP43/ENSG00000120253.8 0.315 TADA1/ENSG00000152382.5 0.314 CTC-273B12.8/ENSG00000269751.1 0.312 FAM13A/ENSG00000138640.10 0.311 ZNF195/ENSG00000005801.12 0.31 AAMP/ENSG00000127837.5 0.31 ZNF609/ENSG00000180357.5 0.309 XYLT2/ENSG00000015532.5 0.309 DDX19B/ENSG00000157349.11 0.309 TCF7L1-IT1/ENSG00000231134.1 0.308 PRKD3/ENSG00000115825.5 0.308 NSMAF/ENSG00000035681.3 0.307 RP11-110G21.2/ENSG00000253475.1 0.305 RYK/ENSG00000163785.7 0.305 DAAM1/ENSG00000100592.11 0.304 ECI2/ENSG00000198721.8 0.304 IFT122/ENSG00000163913.7 0.303 FBLIM1/ENSG00000162458.8 0.301 RPSAP58/ENSG00000205246.4 0.301 CPSF6/ENSG00000111605.12 0.3 DPYSL2/ENSG00000092964.11 0.299 TUG1/ENSG00000253352.4 0.298 LRRC8A/ENSG00000136802.7 0.297 MORC2-AS1/ENSG00000235989.2 0.297 PSIP1/ENSG00000164985.10 0.295 TMPO/ENSG00000120802.9 0.293 ZNF738/ENSG00000172687.9 0.292 LRRN1/ENSG00000175928.5 0.292 RP11-15H20.6/ENSG00000213971.3 0.289 FGD6/ENSG00000180263.9 0.289 RBM4B/ENSG00000173914.6 0.289 ZNF426/ENSG00000130818.6 0.288 B4GALT1/ENSG00000086062.8 0.288 FGF13/ENSG00000129682.9 0.288 UBXN2B/ENSG00000215114.3 0.288 CPSF3/ENSG00000119203.9 0.287 HAT1/ENSG00000128708.8 0.286 MSH6/ENSG00000116062.8 0.286 HUWE1/ENSG00000086758.11 0.286 ANKRD20A11P/ENSG00000215559.4 0.285 ADNP/ENSG00000101126.10 0.284 C16ORF62/ENSG00000103544.10 0.284 ZDHHC4/ENSG00000136247.10 0.284 MRFAP1L1/ENSG00000178988.10 0.284 SLC48A1/ENSG00000211584.9 0.284 POLI/ENSG00000101751.6 0.284 UACA/ENSG00000137831.10 0.283 LAMA1/ENSG00000101680.9 0.283 MXI1/ENSG00000119950.16 0.282 EIF2B4/ENSG00000115211.11 0.28 STK38L/ENSG00000211455.3 0.28 CASP8AP2/ENSG00000118412.8 0.28 RAD50/ENSG00000113522.9 0.279 SLC44A2/ENSG00000129353.10 0.277 EFCAB2/ENSG00000203666.8 0.277 KIF22/ENSG00000079616.8 0.277 CEP70/ENSG00000114107.4 0.276 SLC35B4/ENSG00000205060.6 0.275 LBH/ENSG00000213626.7 0.275 C3ORF38/ENSG00000179021.4 0.275 LGR4/ENSG00000205213.9 0.275 LTBP1/ENSG00000049323.11 0.274 TUSC3/ENSG00000104723.16 0.273 HNRNPM/ENSG00000099783.7 0.273 HIBCH/ENSG00000198130.10 0.273 PRDX6/ENSG00000117592.8 0.271 ZBTB44/ENSG00000196323.7 0.27 NLN/ENSG00000123213.18 0.27 C11ORF74/ENSG00000166352.11 0.27 PRTFDC1/ENSG00000099256.14 0.27 NME4/ENSG00000103202.8 0.267 EYA3/ENSG00000158161.11 0.267 RP11-216F19.2/ENSG00000270674.1 0.267 HINFP/ENSG00000172273.8 0.267 RAB13/ENSG00000143545.4 0.266 CTD-2561J22.5/ENSG00000268119.1 0.266 KAT6B/ENSG00000156650.8 0.265 PTPRG/ENSG00000144724.14 0.264 MACF1/ENSG00000127603.19 0.261 RPL15P3/ENSG00000212802.3 0.26 PSMC6/ENSG00000100519.6 0.26 COL4A5/ENSG00000188153.8 0.259 PEF1/ENSG00000162517.8 0.257 FAM117B/ENSG00000138439.10 0.257 SLC19A1/ENSG00000173638.14 0.256 YY1/ENSG00000100811.5 0.255 HNRNPA2B1/ENSG00000122566.16 0.255 AC006116.27/ENSG00000267459.1 0.255 TDP1/ENSG00000042088.9 0.253 PRRC2B/ENSG00000130723.13 0.253 FAM175A/ENSG00000163322.9 0.253 LTA4H/ENSG00000111144.5 0.252 ZNF669/ENSG00000188295.10 0.252 ZNF135/ENSG00000176293.15 0.252 GCDH/ENSG00000105607.8 0.251 SLC39A6/ENSG00000141424.8 0.25 DDAH2/ENSG00000213722.4 0.25 GJC1/ENSG00000182963.5 Overrepresented GO terms in EP #31: Term Pvalue "RNA splicing, via transesterification reactions " 9.93E-11 cellular nitrogen compound metabolic process 3.79E-09 heterocycle metabolic process 5.36E-08 cellular aromatic compound metabolic process 7.14E-08 RNA transport 4.24E-07 mRNA metabolic process 1.91E-06 organic cyclic compound metabolic process 2.37E-06 nucleobase-containing compound transport 2.38E-06 RNA localization 2.61E-06 mRNA export from nucleus 8.65E-06 protein-DNA complex subunit organization 9.11E-06 cellular component organization or biogenesis 2.71E-05 chromatin assembly or disassembly 3.93E-05 ribonucleoprotein complex export from nucleus 4.95E-05 cellular response to stress 6.04E-05 nucleocytoplasmic transport 7.55E-05 nucleic acid-templated transcription 0.000111075 RNA processing 0.000297524 negative regulation of nucleobase-containing compound metabolic process 0.000297524 chromatin modification 0.00030215 "regulation of mRNA splicing, via spliceosome " 0.000374948 cellular macromolecule biosynthetic process 0.00058327 cellular macromolecular complex assembly 0.000924376 cellular component assembly 0.000972015 DNA repair 0.000984373 nucleobase-containing compound biosynthetic process 0.001045283 RNA metabolic process 0.002114249 negative regulation of macromolecule metabolic process 0.002133388 chromatin remodeling 0.003365129 regulation of nucleobase-containing compound metabolic process 0.003427783 meiotic mismatch repair 0.003765929 histone modification 0.004287581 intracellular transport of virus 0.004673557 multi-organism cellular localization 0.005270372 double-strand break repair 0.005896462 negative regulation of biosynthetic process 0.0059589 ribonucleoprotein complex subunit organization 0.006476449 peptidyl-lysine modification 0.007754654 "mRNA splicing, via spliceosome " 0.008248871 regulation of mRNA metabolic process 0.008522178 nucleosome assembly 0.008548848 regulation of DNA recombination 0.010027149 multi-organism transport 0.010344038 "alternative mRNA splicing, via spliceosome " 0.010947668 regulation of RNA polymerase II transcriptional preinitiation complex assembly 0.011716719 male sex differentiation 0.012394013 organic substance biosynthetic process 0.01303106 gene expression 0.014752103 nucleic acid metabolic process 0.014888772 negative regulation of RNA biosynthetic process 0.018866084 biological regulation 0.019328757 chromosome organization 0.019601063 negative regulation of cell cycle process 0.020607181 DNA packaging 0.022378351 negative regulation of telomere maintenance 0.022579831 negative regulation of RNA splicing 0.022579831 somatic diversification of immune receptors via germline recombination within a single locus 0.02445159 negative regulation of organelle organization 0.025139198 regulation of cellular process 0.02703988 mRNA splice site selection 0.027536803 regulation of macromolecule metabolic process 0.027677184 negative regulation of apoptotic signaling pathway 0.030435001 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition 0.032269878 posttranscriptional regulation of gene expression 0.03398184 "regulation of transcription, DNA-templated " 0.034764228 negative regulation of cellular process 0.035308058 sister chromatid cohesion 0.036888276 male gonad development 0.036888276 spliceosomal complex assembly 0.038152202 "negative regulation of transcription, DNA-templated " 0.038418844 nucleosome disassembly 0.039163167 regulation of RNA biosynthetic process 0.039462164 internal peptidyl-lysine acetylation 0.044801974 metabolic process 0.048887598 --------------------------------------------- "EP #32: 60 cells, 30 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0.0634920634920635, stage2_: 0.161764705882353, stage3_: 0.142857142857143, St4_3_: 0.0919540229885057, stage4: 0.0857142857142857, St5_3_: 0.0273972602739726, stage5_: 0.078125, stage6.2_: 0.134146341463415, stage6.7_: 0.0263157894736842, stage6.14_: 0.0149253731343284, " Top Genes: 0.734 STAU2/ENSG00000040341.13 0.645 ZNF165/ENSG00000197279.3 0.558 NDUFA9P1/ENSG00000237406.1 0.457 SLC4A8/ENSG00000050438.12 0.445 AL136218.1/ENSG00000215462.1 0.438 GAPDHP62/ENSG00000251013.1 0.417 SNCA/ENSG00000145335.11 0.405 RWDD2A/ENSG00000013392.5 0.398 NOVA1/ENSG00000139910.15 0.387 TSTD2/ENSG00000136925.10 0.36 PTPN6/ENSG00000111679.11 0.327 OVGP1/ENSG00000085465.11 0.318 TRMT12/ENSG00000183665.4 0.304 FDX1L/ENSG00000267673.2 0.301 ADAT2/ENSG00000189007.10 0.301 TAF12/ENSG00000120656.7 0.297 CLCP1/ENSG00000232305.1 0.296 PGAP2/ENSG00000148985.15 0.286 WDR67/ENSG00000156787.12 0.278 TBCK/ENSG00000145348.11 0.277 IL10RB/ENSG00000243646.4 0.275 CPXM1/ENSG00000088882.7 0.272 MDM1/ENSG00000111554.10 0.266 EIF4ENIF1/ENSG00000184708.12 0.256 RP11-569A2.2/ENSG00000219150.2 0.256 VAMP5/ENSG00000168899.4 0.255 XRCC4/ENSG00000152422.11 0.254 CTD-2147F2.1/ENSG00000259485.1 0.251 AL035252.1/ENSG00000268302.1 0.25 RNF139/ENSG00000170881.4 Overrepresented GO terms in EP #32: Term Pvalue protein destabilization 0.033929004 tRNA wobble adenosine to inosine editing 0.048494645 negative regulation of dopamine uptake involved in synaptic transmission 0.048494645 negative regulation of norepinephrine uptake 0.048494645 negative regulation of thrombin receptor signaling pathway 0.048494645 positive regulation of glutathione peroxidase activity 0.048494645 positive regulation of hydrogen peroxide catabolic process 0.048494645 --------------------------------------------- "EP #33: 66 cells, 397 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0, stage4: 0, St5_3_: 0, stage5_: 0, stage6.2_: 0.0487804878048781, stage6.7_: 0.526315789473684, stage6.14_: 0.328358208955224, " Top Genes: 3.076 AFP/ENSG00000081051.3 2.026 TSPAN8/ENSG00000127324.4 1.936 FABP1/ENSG00000163586.5 1.903 AGR2/ENSG00000106541.7 1.732 PTP4A1/ENSG00000112245.6 1.727 MBOAT1/ENSG00000172197.9 1.721 ACE2/ENSG00000130234.6 1.715 MGLL/ENSG00000074416.9 1.679 TM4SF1/ENSG00000169908.6 1.675 APOA1/ENSG00000118137.5 1.574 PLAC8/ENSG00000145287.6 1.517 CA2/ENSG00000104267.5 1.493 CEACAM6/ENSG00000086548.8 1.462 CEACAM7/ENSG00000007306.10 1.449 CDH17/ENSG00000079112.5 1.443 GCNT3/ENSG00000140297.8 1.43 ALDH1A1/ENSG00000165092.8 1.429 AL590714.1/ENSG00000268387.1 1.421 TMEM45B/ENSG00000151715.3 1.412 CD44/ENSG00000026508.12 1.406 ATP1A1/ENSG00000163399.11 1.406 S100P/ENSG00000163993.6 1.396 PRSS3/ENSG00000010438.12 1.392 LDHA/ENSG00000134333.9 1.348 GSTO1/ENSG00000148834.8 1.34 CYCS/ENSG00000172115.4 1.319 HGD/ENSG00000113924.7 1.312 PLIN2/ENSG00000147872.5 1.311 LGALS3/ENSG00000131981.11 1.297 IDH1/ENSG00000138413.9 1.28 RDH10/ENSG00000121039.5 1.276 S100A14/ENSG00000189334.4 1.264 CTSB/ENSG00000164733.16 1.264 FXYD3/ENSG00000089356.12 1.255 DHRS3/ENSG00000162496.4 1.252 TCF7L2/ENSG00000148737.11 1.238 IL32/ENSG00000008517.12 1.227 MUC13/ENSG00000173702.3 1.22 NAMPT/ENSG00000105835.7 1.201 SLC7A7/ENSG00000155465.14 1.198 SLPI/ENSG00000124107.5 1.196 MTTP/ENSG00000138823.8 1.187 CALML4/ENSG00000129007.10 1.187 SEBOX/ENSG00000109072.7 1.175 MGST2/ENSG00000085871.4 1.17 SERPINB6/ENSG00000124570.13 1.16 RHOC/ENSG00000155366.11 1.14 CASP3/ENSG00000164305.13 1.138 APOA2/ENSG00000158874.6 1.128 AADAC/ENSG00000114771.8 1.123 RP11-139K1.2/ENSG00000227560.1 1.12 TFF1/ENSG00000160182.2 1.111 IFI27/ENSG00000165949.8 1.11 PSME2/ENSG00000100911.9 1.108 PTGR1/ENSG00000106853.12 1.105 CLDN7/ENSG00000181885.14 1.104 SCARNA22/ENSG00000249784.1 1.095 AGR3/ENSG00000173467.4 1.092 FAM13A/ENSG00000138640.10 1.073 TOB1/ENSG00000141232.4 1.069 PDGFA/ENSG00000197461.9 1.054 HSD17B11/ENSG00000198189.6 1.046 RBP2/ENSG00000114113.2 1.029 PON2/ENSG00000105854.8 1.026 HPGD/ENSG00000164120.9 1.007 S100A13/ENSG00000189171.8 0.999 SPTBN1/ENSG00000115306.11 0.994 GPRC5A/ENSG00000013588.5 0.984 ALB/ENSG00000163631.12 0.984 RAP2B/ENSG00000181467.2 0.981 STOM/ENSG00000148175.8 0.98 TNFAIP2/ENSG00000185215.4 0.977 KRT19/ENSG00000171345.9 0.975 KLF6/ENSG00000067082.10 0.943 LMO7/ENSG00000136153.14 0.941 TNFRSF11B/ENSG00000164761.4 0.938 SLC16A1/ENSG00000155380.7 0.928 BLNK/ENSG00000095585.12 0.925 CEACAM1/ENSG00000079385.17 0.914 OCLN/ENSG00000197822.6 0.903 PSMB8/ENSG00000204264.4 0.902 LIMA1/ENSG00000050405.9 0.902 FABP3/ENSG00000121769.3 0.898 HSD17B2/ENSG00000086696.4 0.892 TAPBP/ENSG00000231925.7 0.886 PLAUR/ENSG00000011422.7 0.88 SLC9A3R1/ENSG00000109062.5 0.875 CHP1/ENSG00000187446.7 0.861 IFNGR1/ENSG00000027697.8 0.859 CEACAM5/ENSG00000105388.10 0.859 PSMB9/ENSG00000240065.3 0.858 SCGN/ENSG00000079689.9 0.852 OAS1/ENSG00000089127.8 0.848 OTC/ENSG00000036473.5 0.843 TMEM176B/ENSG00000106565.13 0.836 HLA-A/ENSG00000206503.7 0.83 ISG20/ENSG00000172183.10 0.826 LRRC16A/ENSG00000079691.15 0.821 ANXA10/ENSG00000109511.6 0.821 DPP4/ENSG00000197635.5 0.82 PLSCR1/ENSG00000188313.8 0.814 PDE4D/ENSG00000113448.12 0.811 SERPINA1/ENSG00000197249.8 0.811 B4GALT1/ENSG00000086062.8 0.808 AL358113.1/ENSG00000269295.1 0.807 ANPEP/ENSG00000166825.9 0.802 MSRB1/ENSG00000198736.7 0.788 CDH1/ENSG00000039068.13 0.78 CYP2C9/ENSG00000138109.9 0.773 CTNND1/ENSG00000198561.8 0.76 INPP1/ENSG00000151689.8 0.759 GMNN/ENSG00000112312.5 0.753 C19ORF33/ENSG00000167644.7 0.75 SLC15A1/ENSG00000088386.11 0.744 COX7B/ENSG00000131174.4 0.742 MSMB/ENSG00000138294.9 0.734 SPATS2L/ENSG00000196141.7 0.733 TMEM106C/ENSG00000134291.7 0.732 DHRS7/ENSG00000100612.9 0.723 GLRX/ENSG00000173221.9 0.718 ARL4A/ENSG00000122644.8 0.715 ACY1/ENSG00000243989.3 0.701 LACTB2/ENSG00000147592.4 0.693 C20ORF24/ENSG00000101084.12 0.692 RARRES3/ENSG00000133321.6 0.679 SMIM15/ENSG00000188725.3 0.674 TMEM141/ENSG00000244187.2 0.674 C8ORF4/ENSG00000176907.3 0.673 CYC1/ENSG00000179091.4 0.67 LIPC/ENSG00000166035.6 0.669 GBP3/ENSG00000117226.7 0.657 AKR1C2/ENSG00000151632.12 0.657 TFPI/ENSG00000003436.10 0.65 NFKBIZ/ENSG00000144802.7 0.65 CP/ENSG00000047457.9 0.647 LIPH/ENSG00000163898.5 0.647 PI3/ENSG00000124102.4 0.646 TTR/ENSG00000118271.5 0.643 PIP5K1B/ENSG00000107242.13 0.641 ATP1B3/ENSG00000069849.6 0.638 S100A6/ENSG00000197956.5 0.637 FLNB/ENSG00000136068.10 0.635 APOC3/ENSG00000110245.7 0.633 RP11-363E7.4/ENSG00000260912.1 0.63 RP11-325F22.5/ENSG00000225329.1 0.629 VDAC1/ENSG00000213585.6 0.622 DNASE1/ENSG00000213918.6 0.619 EML4/ENSG00000143924.14 0.618 SLC25A39/ENSG00000013306.11 0.618 CD2AP/ENSG00000198087.7 0.617 ANXA1/ENSG00000135046.9 0.616 RHOF/ENSG00000139725.2 0.616 CD164/ENSG00000135535.10 0.616 JUP/ENSG00000173801.12 0.61 CLIC1/ENSG00000213719.4 0.607 PRR13/ENSG00000205352.6 0.606 PCK2/ENSG00000100889.7 0.606 MAOA/ENSG00000189221.5 0.605 HERPUD1/ENSG00000051108.10 0.597 UQCRC2/ENSG00000140740.6 0.594 ADK/ENSG00000156110.9 0.594 GPR128/ENSG00000144820.3 0.592 RCAN1/ENSG00000159200.12 0.591 PFN1/ENSG00000108518.7 0.591 POMP/ENSG00000132963.7 0.584 EPCAM/ENSG00000119888.6 0.582 CAB39/ENSG00000135932.6 0.58 GSKIP/ENSG00000100744.10 0.577 PCDH7/ENSG00000169851.11 0.577 SDHD/ENSG00000204370.4 0.575 GSTM4/ENSG00000168765.11 0.574 SLC19A3/ENSG00000135917.9 0.568 FNDC3B/ENSG00000075420.8 0.567 NQO1/ENSG00000181019.8 0.566 MGAT4A/ENSG00000071073.6 0.565 SIAE/ENSG00000110013.8 0.563 FUT2/ENSG00000176920.10 0.561 APOB/ENSG00000084674.9 0.56 RP1-179N16.3/ENSG00000237719.1 0.554 MRPS10/ENSG00000048544.5 0.553 PNRC2/ENSG00000189266.7 0.548 CFLAR/ENSG00000003402.14 0.546 SERPINB1/ENSG00000021355.8 0.545 NHSL1/ENSG00000135540.7 0.531 CLRN3/ENSG00000180745.4 0.531 LAP3/ENSG00000002549.7 0.526 TMEM176A/ENSG00000002933.3 0.522 TNFSF10/ENSG00000121858.6 0.519 GLTP/ENSG00000139433.5 0.519 MPZL3/ENSG00000160588.5 0.518 PPARG/ENSG00000132170.15 0.517 SEC23A/ENSG00000100934.10 0.509 TJP3/ENSG00000105289.10 0.505 GLS/ENSG00000115419.8 0.504 MPC1/ENSG00000060762.14 0.504 RBM47/ENSG00000163694.10 0.504 IL2RG/ENSG00000147168.8 0.503 MUC3A/ENSG00000169894.13 0.502 BMP2K/ENSG00000138756.13 0.501 MRPL18/ENSG00000112110.5 0.501 CHCHD3/ENSG00000106554.7 0.5 NCOA4/ENSG00000138293.15 0.492 SOX9/ENSG00000125398.5 0.492 GK/ENSG00000198814.8 0.491 IL18/ENSG00000150782.7 0.486 CCL20/ENSG00000115009.7 0.482 PARP14/ENSG00000173193.9 0.473 EHF/ENSG00000135373.8 0.47 SULT1A2/ENSG00000197165.6 0.47 ARHGAP26-IT1/ENSG00000230789.1 0.467 FKBP11/ENSG00000134285.6 0.467 PTPRR/ENSG00000153233.8 0.467 SLC18B1/ENSG00000146409.6 0.46 CASP1/ENSG00000137752.18 0.459 P2RX4/ENSG00000135124.10 0.457 C1ORF106/ENSG00000163362.6 0.456 CIDEB/ENSG00000136305.7 0.454 SLC1A5/ENSG00000105281.8 0.452 SLCO3A1/ENSG00000176463.8 0.447 AKAP13/ENSG00000170776.15 0.447 GPI/ENSG00000105220.9 0.442 FUCA2/ENSG00000001036.8 0.442 XRCC4/ENSG00000152422.11 0.438 CORO2A/ENSG00000106789.8 0.438 FAR2/ENSG00000064763.5 0.436 S100A4/ENSG00000196154.7 0.436 FAM46A/ENSG00000112773.11 0.435 GBP1/ENSG00000117228.9 0.435 ZNF165/ENSG00000197279.3 0.432 GPR126/ENSG00000112414.10 0.431 HAVCR1/ENSG00000113249.8 0.431 TMEM37/ENSG00000171227.6 0.431 CLIC5/ENSG00000112782.11 0.43 NME1-NME2/ENSG00000243678.6 0.428 SPAG9/ENSG00000008294.16 0.427 RP11-59D5__B.2/ENSG00000236345.1 0.426 MDM2/ENSG00000135679.17 0.423 GDA/ENSG00000119125.12 0.422 CDR2L/ENSG00000109089.7 0.422 BAIAP2L1/ENSG00000006453.9 0.419 GAREM/ENSG00000141441.11 0.418 FAM32A/ENSG00000105058.7 0.418 KIAA1217/ENSG00000120549.11 0.416 C3/ENSG00000125730.12 0.414 UBE2L6/ENSG00000156587.11 0.413 RHOU/ENSG00000116574.4 0.412 ABCC3/ENSG00000108846.11 0.41 ATP1B1/ENSG00000143153.7 0.406 GSDMB/ENSG00000073605.14 0.405 CARD16/ENSG00000204397.3 0.405 AVPI1/ENSG00000119986.6 0.405 RP11-268I9.1/ENSG00000243303.1 0.405 AK8/ENSG00000165695.5 0.402 CXADR/ENSG00000154639.14 0.399 ACSL5/ENSG00000197142.6 0.397 AUP1/ENSG00000115307.12 0.396 PCSK5/ENSG00000099139.9 0.394 LGALS2/ENSG00000100079.5 0.394 UGT8/ENSG00000174607.6 0.393 PDHA1/ENSG00000131828.9 0.391 F2RL1/ENSG00000164251.4 0.388 PARD6B/ENSG00000124171.4 0.388 SOD2/ENSG00000112096.11 0.388 CGN/ENSG00000143375.9 0.388 TDO2/ENSG00000151790.4 0.383 GIPC2/ENSG00000137960.5 0.379 CEBPG/ENSG00000153879.3 0.379 LAD1/ENSG00000159166.9 0.377 CTSS/ENSG00000163131.5 0.376 PROCR/ENSG00000101000.4 0.373 IFI30/ENSG00000216490.2 0.373 CD55/ENSG00000196352.9 0.372 ANXA11/ENSG00000122359.13 0.372 RP11-569G9.7/ENSG00000225854.2 0.371 ANXA13/ENSG00000104537.12 0.37 SLC51B/ENSG00000186198.3 0.37 DDAH1/ENSG00000153904.14 0.369 PAQR3/ENSG00000163291.10 0.362 DDC/ENSG00000132437.13 0.36 CD9/ENSG00000010278.7 0.359 SLC30A7/ENSG00000162695.7 0.359 RPL7AP34/ENSG00000213312.3 0.356 HEPH/ENSG00000089472.12 0.356 CBWD5/ENSG00000147996.12 0.355 CPD/ENSG00000108582.7 0.354 ABHD11/ENSG00000106077.14 0.351 ERBB3/ENSG00000065361.10 0.35 AGPAT2/ENSG00000169692.8 0.349 C12ORF75/ENSG00000235162.4 0.348 DMBT1/ENSG00000187908.11 0.348 AC107016.1/ENSG00000225410.1 0.348 PNPO/ENSG00000108439.5 0.347 CTB-118N6.3/ENSG00000248445.1 0.343 CHMP2B/ENSG00000083937.4 0.343 EFNB2/ENSG00000125266.6 0.34 ASS1/ENSG00000130707.13 0.338 HLA-B/ENSG00000234745.5 0.334 IFI35/ENSG00000068079.3 0.334 ACOX2/ENSG00000168306.8 0.333 ASL/ENSG00000126522.12 0.333 RHOG/ENSG00000177105.9 0.333 MYO1E/ENSG00000157483.4 0.331 MUC3A/ENSG00000228273.2 0.329 CLCN3/ENSG00000109572.9 0.326 BSG/ENSG00000172270.14 0.321 KYNU/ENSG00000115919.10 0.321 PSEN1/ENSG00000080815.14 0.319 USH1C/ENSG00000006611.10 0.319 CD58/ENSG00000116815.11 0.318 PSMB10/ENSG00000205220.7 0.316 BCL10/ENSG00000142867.8 0.316 LY6G5C/ENSG00000204428.8 0.315 GNG12/ENSG00000172380.5 0.315 CTSA/ENSG00000064601.11 0.314 TTC22/ENSG00000006555.6 0.314 INTS12/ENSG00000138785.10 0.313 CLDN18/ENSG00000066405.8 0.313 MACC1/ENSG00000183742.8 0.31 HLA-C/ENSG00000204525.10 0.309 CASP8/ENSG00000064012.17 0.309 HADHA/ENSG00000084754.6 0.307 TMEM2/ENSG00000135048.9 0.307 TAPBPL/ENSG00000139192.7 0.305 RNF128/ENSG00000133135.9 0.304 CTSE/ENSG00000196188.6 0.304 LY6E/ENSG00000160932.6 0.304 MIR22HG/ENSG00000186594.6 0.302 FER1L6/ENSG00000214814.2 0.301 HNF4G/ENSG00000164749.7 0.3 TPMT/ENSG00000137364.4 0.298 RIOK3/ENSG00000101782.10 0.297 IL1RAP/ENSG00000196083.5 0.296 CYP3A5/ENSG00000106258.9 0.295 RP11-161H23.5/ENSG00000258232.2 0.293 NCOA7/ENSG00000111912.14 0.293 CREB3L3/ENSG00000060566.9 0.292 NR1H4/ENSG00000012504.9 0.292 HIGD2A/ENSG00000146066.2 0.292 RP11-106J23.2/ENSG00000255185.1 0.288 "AC011897.1,FAM84A/ENSG00000162981.12" 0.288 A1CF/ENSG00000148584.9 0.286 CASP7/ENSG00000165806.15 0.286 CTSH/ENSG00000103811.11 0.284 C11ORF24/ENSG00000171067.6 0.283 VAMP8/ENSG00000118640.6 0.283 QRSL1/ENSG00000130348.7 0.283 TM4SF5/ENSG00000142484.5 0.281 RGS16/ENSG00000143333.6 0.281 MUC1/ENSG00000185499.12 0.28 GSTK1/ENSG00000197448.9 0.28 LGALS3BP/ENSG00000108679.7 0.279 PHYHIPL/ENSG00000165443.7 0.278 MYBPC1/ENSG00000196091.8 0.277 MRPS36/ENSG00000134056.7 0.277 RAB27B/ENSG00000041353.5 0.277 C19ORF40/ENSG00000131944.5 0.276 TJP2/ENSG00000119139.11 0.276 SLC35D2/ENSG00000130958.7 0.273 SCPEP1/ENSG00000121064.8 0.273 RP11-73M18.10/ENSG00000269910.1 0.273 ST7/ENSG00000004866.14 0.271 PSAT1/ENSG00000135069.9 0.271 EDEM1/ENSG00000134109.6 0.27 AC064853.4/ENSG00000240115.1 0.27 GALM/ENSG00000143891.12 0.27 ZNF503-AS1/ENSG00000226051.2 0.269 SLC5A5/ENSG00000105641.3 0.268 CFI/ENSG00000205403.8 0.267 RP11-48O20.4/ENSG00000224259.1 0.267 SPINT1/ENSG00000166145.10 0.267 RP11-571F15.3/ENSG00000233668.1 0.266 PPARGC1B/ENSG00000155846.12 0.265 RP11-242C19.2/ENSG00000241886.1 0.265 ZNF609/ENSG00000180357.5 0.264 PRKCA/ENSG00000154229.7 0.263 PNKD/ENSG00000127838.9 0.263 TFF2/ENSG00000160181.4 0.263 TMCC3/ENSG00000057704.6 0.262 COPG1/ENSG00000181789.10 0.262 GATM/ENSG00000171766.11 0.262 AHR/ENSG00000106546.8 0.261 RAB14/ENSG00000119396.6 0.261 MPRIP-AS1/ENSG00000225442.2 0.26 EFEMP1/ENSG00000115380.14 0.259 KLF3/ENSG00000109787.8 0.258 ETFDH/ENSG00000171503.7 0.257 ALG2/ENSG00000119523.8 0.257 C1ORF21/ENSG00000116667.7 0.256 FBXO34/ENSG00000178974.5 0.254 TMEM87A/ENSG00000103978.11 0.254 KLF4/ENSG00000136826.10 0.252 SLC20A1/ENSG00000144136.6 0.251 VSNL1/ENSG00000163032.7 0.251 CDKN1A/ENSG00000124762.8 0.25 CALCOCO2/ENSG00000136436.9 0.25 RNF213/ENSG00000173821.15 0.25 MXD1/ENSG00000059728.6 Overrepresented GO terms in EP #33: Term Pvalue oxoacid metabolic process 2.17E-09 regulation of peptidase activity 5.59E-09 cellular ketone metabolic process 2.70E-07 neutral lipid catabolic process 1.82E-06 cellular response to chemical stimulus 3.21E-06 monocarboxylic acid metabolic process 4.32E-06 regulation of cysteine-type endopeptidase activity 7.59E-06 glycerolipid catabolic process 2.01E-05 oxidation-reduction process 3.81E-05 negative regulation of endopeptidase activity 4.08E-05 cellular lipid metabolic process 5.36E-05 response to interferon-gamma 6.19E-05 biological adhesion 8.28E-05 antigen processing and presentation of peptide antigen via MHC class I 0.000134513 negative regulation of proteolysis 0.000142023 organic anion transport 0.00017096 response to stress 0.000182313 acylglycerol metabolic process 0.000183846 cellular amine metabolic process 0.00022411 response to bacterium 0.00028312 urea metabolic process 0.000377183 negative regulation of very-low-density lipoprotein particle remodeling 0.000432421 protein processing 0.000453103 wound healing 0.000505431 terpenoid metabolic process 0.000541647 retinoid metabolic process 0.000569764 small molecule metabolic process 0.000622875 monocarboxylic acid transport 0.000640464 response to organic substance 0.000947099 cellular catabolic process 0.001219627 triglyceride catabolic process 0.001439162 response to external biotic stimulus 0.001598965 entry into host 0.001613558 entry into cell of other organism involved in symbiotic interaction 0.001613558 xenobiotic metabolic process 0.001749858 positive regulation of endopeptidase activity 0.001753798 interaction with host 0.001761224 response to lipopolysaccharide 0.001767118 regulation of immune response 0.00177778 response to organonitrogen compound 0.001827725 triglyceride-rich lipoprotein particle remodeling 0.001852738 arginine metabolic process 0.001992816 plasma lipoprotein particle assembly 0.001992816 regulation of catalytic activity 0.002004302 viral process 0.002765002 leukocyte migration 0.00289114 single-organism metabolic process 0.003168059 regulation of sodium ion transport 0.003182835 interferon-gamma-mediated signaling pathway 0.003182835 single-multicellular organism process 0.003400498 carboxylic acid biosynthetic process 0.003563543 response to toxic substance 0.003675429 cholesterol homeostasis 0.003706687 regulation of protein stability 0.003780722 acute inflammatory response 0.0038623 hemostasis 0.003903448 negative regulation of molecular function 0.004002963 oligopeptide transmembrane transport 0.00417786 multi-organism process 0.004226291 protein-lipid complex remodeling 0.004264378 hormone metabolic process 0.004618873 regulation of defense response 0.004640644 cellular response to tumor necrosis factor 0.00491288 response to xenobiotic stimulus 0.004968183 positive regulation of response to stimulus 0.005514165 regulation of cellular amino acid metabolic process 0.005541553 type I interferon signaling pathway 0.005716998 viral entry into host cell 0.005822882 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.005855046 cell-cell junction assembly 0.006116759 interleukin-2 production 0.006279052 cell motility 0.006887632 single organism signaling 0.007646172 response to type I interferon 0.007752117 response to estrogen 0.007752117 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.007907343 negative regulation of lipase activity 0.008210329 bile acid and bile salt transport 0.009877875 regulation of sodium ion transmembrane transporter activity 0.010038356 cytokine biosynthetic process 0.01017019 regulation of fatty acid metabolic process 0.010346642 homeostatic process 0.01047337 antigen processing and presentation 0.010695943 high-density lipoprotein particle remodeling 0.010994031 post-embryonic animal organ development 0.010994031 "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent " 0.011249333 negative regulation of cytokine secretion 0.011534641 positive regulation of proteolysis 0.011767434 lipid homeostasis 0.012184825 epithelial cell differentiation 0.012219771 regulation of signaling 0.012227906 response to hormone 0.013323196 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0.013610753 negative regulation of hydrolase activity 0.013738587 cellular response to cytokine stimulus 0.013850411 negative regulation of programmed cell death 0.013939075 interleukin-1 alpha production 0.014128701 reverse cholesterol transport 0.014394597 small molecule catabolic process 0.014947057 activation of immune response 0.01496015 cell surface receptor signaling pathway 0.015534525 intestinal absorption 0.016853567 regulation of tissue remodeling 0.017163892 response to organic cyclic compound 0.017381248 regulation of blood coagulation 0.017667531 digestion 0.017732397 relaxation of cardiac muscle 0.018484807 pyridoxine biosynthetic process 0.018935973 cytidine to uridine editing 0.018935973 tryptophan catabolic process to acetyl-CoA 0.018935973 arginine biosynthetic process via ornithine 0.018935973 negative regulation of cholesterol import 0.018935973 regulation of cholesterol transporter activity 0.018935973 regulation of cardiac muscle contraction 0.018973379 negative regulation of cell adhesion 0.019001892 organic substance catabolic process 0.020030981 cell communication 0.020528433 positive regulation of transport 0.020808088 single organismal cell-cell adhesion 0.021217692 regulation of protein localization 0.0212644 "antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent " 0.022221584 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c 0.022221584 triglyceride homeostasis 0.023223679 positive regulation of sodium ion transmembrane transport 0.023338628 positive regulation of establishment of protein localization 0.025216775 negative regulation of coagulation 0.027511696 antigen processing and presentation of exogenous peptide antigen 0.027903437 response to metal ion 0.029021157 lipid digestion 0.029030844 immune effector process 0.029744737 positive regulation of immune system process 0.030076754 regulation of calcium-mediated signaling 0.03042609 regulation of systemic arterial blood pressure mediated by a chemical signal 0.031243604 tissue development 0.032071945 innate immune response 0.032424364 regulation of cytokine secretion involved in immune response 0.03276631 high-density lipoprotein particle clearance 0.03276631 sterol import 0.03276631 regulation of interleukin-8 biosynthetic process 0.03276631 regulation of biological quality 0.033264174 actin filament-based process 0.03418125 glutamine family amino acid biosynthetic process 0.035636726 glutathione derivative biosynthetic process 0.035636726 organonitrogen compound metabolic process 0.036258513 lipid catabolic process 0.03673798 regulation of protein transport 0.040343236 response to nutrient 0.040407909 lipid transport 0.040547932 tissue homeostasis 0.04085858 single-organism biosynthetic process 0.041279849 cell-cell adhesion 0.041860777 regulation of response to wounding 0.042444104 response to immobilization stress 0.043231712 pyridine-containing compound biosynthetic process 0.043231712 second-messenger-mediated signaling 0.045364998 regulation of triglyceride catabolic process 0.046014984 low-density lipoprotein particle remodeling 0.046014984 sodium ion export from cell 0.046014984 regulation of phospholipid biosynthetic process 0.046014984 interleukin-8 production 0.04675751 immune system process 0.047273869 localization 0.049714467 --------------------------------------------- "EP #34: 18 cells, 58 genes" "Fraction of cells from each time pt- hesc_: 0.0188679245283019, stage1_: 0, stage2_: 0.205882352941176, stage3_: 0.0285714285714286, St4_3_: 0.0114942528735632, stage4: 0, St5_3_: 0, stage5_: 0, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0, " Top Genes: 1.99 TPD52L1/ENSG00000111907.16 1.611 RP11-189B4.6/ENSG00000231817.2 1.262 SCN7A/ENSG00000136546.9 1.11 GLYATL1/ENSG00000166840.9 1.019 FAM46A/ENSG00000112773.11 1.019 C1ORF54/ENSG00000118292.4 0.95 STOM/ENSG00000148175.8 0.857 EPHX2/ENSG00000120915.9 0.819 AL356740.1/ENSG00000234603.2 0.763 ISL1/ENSG00000016082.10 0.728 GLYATL1P2/ENSG00000254717.2 0.708 RNASE4/ENSG00000258818.1 0.705 LAMB2/ENSG00000172037.9 0.689 NCOA2/ENSG00000140396.8 0.675 RTN1/ENSG00000139970.12 0.638 RNASE1/ENSG00000129538.9 0.513 RP11-388M20.6/ENSG00000260304.1 0.504 C1QTNF3/ENSG00000082196.15 0.488 SFI1/ENSG00000198089.10 0.475 RP11-318C24.2/ENSG00000227740.1 0.47 DUTP6/ENSG00000225171.2 0.469 HNMT/ENSG00000150540.9 0.465 CNTN5/ENSG00000149972.6 0.461 SETMAR/ENSG00000170364.8 0.46 RP11-860B13.3/ENSG00000256512.1 0.449 SCML1/ENSG00000047634.10 0.412 PTMAP1/ENSG00000228415.2 0.408 THADA/ENSG00000115970.14 0.399 ADAMTS1/ENSG00000154734.9 0.395 RP11-460E7.8/ENSG00000235893.5 0.394 VN1R108P/ENSG00000230772.1 0.374 LCP1/ENSG00000136167.9 0.372 ZNF19/ENSG00000157429.11 0.361 WNT5A/ENSG00000114251.9 0.359 TAGLN3/ENSG00000144834.8 0.339 PIN4P1/ENSG00000227973.1 0.339 AMPH/ENSG00000078053.12 0.336 GPHA2/ENSG00000149735.2 0.336 PCOLCE2/ENSG00000163710.3 0.334 SLC25A1/ENSG00000100075.5 0.33 PGAP2/ENSG00000148985.15 0.321 KCTD2/ENSG00000180901.6 0.321 RP11-47J17.2/ENSG00000203258.3 0.314 FOXP1-IT1/ENSG00000242094.1 0.303 OXCT1/ENSG00000083720.8 0.296 AL445989.1/ENSG00000226974.2 0.294 ELL2/ENSG00000118985.10 0.294 HMGB1P41/ENSG00000253516.1 0.291 LINC00618/ENSG00000225163.3 0.287 RP11-473M10.3/ENSG00000237378.1 0.285 RP1-89D4.1/ENSG00000241255.1 0.283 RP1-127B20.4/ENSG00000223730.1 0.283 AC091729.9/ENSG00000229043.2 0.281 HIBADH/ENSG00000106049.3 0.278 RP11-119H12.1/ENSG00000241002.1 0.277 ADPRHL2/ENSG00000116863.10 0.265 RP11-277I20.3/ENSG00000220739.2 0.252 FBXO27/ENSG00000161243.4 Overrepresented GO terms in EP #34: Term Pvalue positive regulation of establishment of protein localization 0.001659632 regulation of protein localization 0.012625038 positive regulation of protein secretion 0.024285748 regulation of intracellular protein transport 0.02646603 regulation of cellular localization 0.0323482 regulation of interleukin-6 production 0.033906599 --------------------------------------------- "EP #35: 21 cells, 24 genes" "Fraction of cells from each time pt- hesc_: 0.0754716981132075, stage1_: 0.111111111111111, stage2_: 0.0147058823529412, stage3_: 0.0285714285714286, St4_3_: 0.0344827586206897, stage4: 0.0142857142857143, St5_3_: 0, stage5_: 0.03125, stage6.2_: 0, stage6.7_: 0, stage6.14_: 0.0149253731343284, " Top Genes: 2.953 MT1X/ENSG00000187193.8 2.634 MT1G/ENSG00000125144.9 2.557 MT2A/ENSG00000125148.6 2.106 MT1E/ENSG00000169715.10 1.989 MT1F/ENSG00000198417.5 1.477 MT1H/ENSG00000205358.3 0.558 PIGA/ENSG00000165195.9 0.45 CYB5R1/ENSG00000159348.8 0.444 CTB-151G24.1/ENSG00000267696.2 0.437 JMJD8/ENSG00000161999.6 0.427 MT1M/ENSG00000205364.3 0.387 TUBGCP2/ENSG00000130640.9 0.366 FUT11/ENSG00000196968.5 0.356 RP11-52I18.1/ENSG00000223450.1 0.349 ZNF383/ENSG00000188283.7 0.343 ZFAND4/ENSG00000172671.15 0.306 ALDH1B1/ENSG00000137124.6 0.299 RP11-196G18.23/ENSG00000264207.1 0.295 ZNF200/ENSG00000010539.7 0.293 RP11-789C1.1/ENSG00000250266.1 0.283 RUSC1/ENSG00000160753.11 0.259 RP11-199F11.2/ENSG00000262251.1 0.258 AC008264.4/ENSG00000224545.1 0.255 BNIP3P1/ENSG00000197358.8 Overrepresented GO terms in EP #35: Term Pvalue cellular response to zinc ion 1.42E-16 cellular response to cadmium ion 3.58E-11 cellular response to inorganic substance 1.24E-09 negative regulation of growth 2.30E-08 response to transition metal nanoparticle 4.80E-07 response to metal ion 6.72E-05 cellular response to erythropoietin 0.00020555 response to copper ion 0.006448563 --------------------------------------------- "EP #36: 15 cells, 57 genes" "Fraction of cells from each time pt- hesc_: 0, stage1_: 0, stage2_: 0, stage3_: 0, St4_3_: 0.0114942528735632, stage4: 0.0285714285714286, St5_3_: 0.0136986301369863, stage5_: 0, stage6.2_: 0.0853658536585366, stage6.7_: 0.0394736842105263, stage6.14_: 0.0149253731343284, " Top Genes: 3.17 IL32/ENSG00000008517.12 1.8 RNU4ATAC/ENSG00000264229.1 1.627 CTSE/ENSG00000196188.6 1.502 UBD/ENSG00000213886.3 1.468 TM4SF1/ENSG00000169908.6 1.428 PLAU/ENSG00000122861.11 1.118 CCL2/ENSG00000108691.4 1.113 APOBEC3B/ENSG00000179750.11 1.09 CALD1/ENSG00000122786.15 1.028 GPRC5B/ENSG00000167191.7 0.957 GXYLT2/ENSG00000172986.8 0.952 NPPB/ENSG00000120937.8 0.818 SVIL/ENSG00000197321.10 0.801 IL23A/ENSG00000110944.4 0.763 SLAIN2/ENSG00000109171.10 0.714 PPAP2C/ENSG00000141934.4 0.697 TNFAIP2/ENSG00000185215.4 0.642 ACTA2/ENSG00000107796.8 0.625 CALCB/ENSG00000175868.9 0.615 BIRC3/ENSG00000023445.9 0.574 ATP10D/ENSG00000145246.9 0.564 APOBEC3G/ENSG00000239713.3 0.56 RP11-473M20.7/ENSG00000261971.2 0.552 MFN1/ENSG00000171109.14 0.526 UNC93A/ENSG00000112494.5 0.506 NNMT/ENSG00000166741.3 0.503 EDN1/ENSG00000078401.6 0.481 LCP1/ENSG00000136167.9 0.478 AC090673.2/ENSG00000267942.1 0.461 RP11-3K24.1/ENSG00000241157.1 0.46 TNFRSF9/ENSG00000049249.4 0.459 MMP12/ENSG00000110347.7 0.432 NECAB3/ENSG00000125967.11 0.428 PLAT/ENSG00000104368.13 0.416 CFL2/ENSG00000165410.10 0.401 MMP10/ENSG00000166670.5 0.377 SERPINA3/ENSG00000196136.11 0.37 CXCL5/ENSG00000163735.6 0.367 SMG9/ENSG00000105771.9 0.358 CSRP2/ENSG00000175183.5 0.352 RP11-211A18.1/ENSG00000236636.2 0.338 MMP7/ENSG00000137673.4 0.322 SPOCK3/ENSG00000196104.6 0.315 RP11-154B12.3/ENSG00000259177.1 0.311 GAPDHP66/ENSG00000250933.1 0.31 RP11-460N20.3/ENSG00000239985.2 0.307 ZBTB20/ENSG00000181722.11 0.306 LCK/ENSG00000182866.12 0.293 PSMB8/ENSG00000204264.4 0.292 RP11-236P24.1/ENSG00000235224.1 0.286 KIAA0040/ENSG00000235750.5 0.283 SLC43A3/ENSG00000134802.12 0.28 IL8/ENSG00000169429.6 0.279 RHOU/ENSG00000116574.4 0.278 ADPRHL2/ENSG00000116863.10 0.254 DUSP10/ENSG00000143507.13 0.254 RP11-115H15.1/ENSG00000257979.1 Overrepresented GO terms in EP #36: Term Pvalue response to external biotic stimulus 1.27E-05 immune effector process 0.000240453 chemokine-mediated signaling pathway 0.00050838 innate immune response 0.000645807 positive regulation of leukocyte chemotaxis 0.001385749 cellular response to tumor necrosis factor 0.001573915 regulation of defense response to virus 0.00354391 regulation of granulocyte chemotaxis 0.00359131 maternal process involved in parturition 0.004813422 response to virus 0.005311745 response to lipopolysaccharide 0.005311745 response to bacterium 0.007228374 negative regulation of transposition 0.011485481 positive regulation of renal sodium excretion 0.011485481 regulation of single stranded viral RNA replication via double stranded DNA intermediate 0.011485481 negative regulation of blood coagulation 0.012159415 positive regulation of response to external stimulus 0.017044384 regulation of response to stress 0.017481822 positive regulation of tumor necrosis factor production 0.01973686 regulation of leukocyte migration 0.020265823 positive regulation of urine volume 0.020935151 localization of cell 0.024908586 positive regulation of cell migration 0.025346157 neutrophil migration 0.027044214 regulation of cell motility 0.027699051 negative regulation of response to external stimulus 0.028526953 cellular response to interleukin-1 0.029813771 negative regulation of interleukin-10 production 0.033113753 positive regulation of cellular component movement 0.034075788 response to cytokine 0.034240358 positive regulation of locomotion 0.034542837 regulation of inflammatory response 0.034822573 negative regulation of response to wounding 0.037508814 regulation of nitric-oxide synthase biosynthetic process 0.037771391 "regulation of symbiosis, encompassing mutualism through parasitism " 0.040700527 multi-organism cellular process 0.044408438 animal organ regeneration 0.04449216 regulation of chemotaxis 0.046069761 positive regulation of defense response to virus by host 0.047973227 vascular smooth muscle contraction 0.047973227 regulation of excretion 0.047973227 positive regulation of neutrophil chemotaxis 0.047973227