Pathway.Name IC.S.Typh.4day.SB1117.C_in.reach IC.S.Typh.4day.SL1344.C_in.reach IC.S.Typh.8hr.SB1117.C_in.reach IC.S.Typh.8hr.SL1344.C_in.reach Drug.AntibioticMix.C_in.reach Diet.Fiber.AX.C_in.reach Diet.Add.Probio.BALBc.C_in.reach Diet.Add.Probio.BALBc.SI_in.reach Diet.Add.Probio.C57BL6.C_in.reach Diet.Add.Probio.C57BL6.SI_in.reach IC.Colitis.C_in.reach Diet.Fat.20.DistalSI_in.reach Diet.Fat.30.DistalSI_in.reach Diet.Fat.45.DistalSI_in.reach Diet.Fat.60.DistalSI_in.reach IC.Flagellin.C_in.reach Diet.Fiber.FOS.C_in.reach Diet.Fiber.GG.C_in.reach Diet.Add.Heme.C_in.reach IC.G.Duodelis.SI_in.reach Diet.Fiber.IN.C_in.reach Drug.HerbalDrug.C_in.reach Drug.HerbalDrug.S_in.reach Diet.Fat.20.MiddleSI_in.reach Diet.Fat.30.MiddleSI_in.reach Diet.Fat.45.MiddleSI_in.reach Drug.Penicillin.SI_in.reach Diet.Fat.20.ProximalSI_in.reach Diet.Fat.30.ProximalSI_in.reach Diet.Fat.45.ProximalSI_in.reach Diet.Fat.60.ProximalSI_in.reach Diet.Fiber.RS.C_in.reach Drug.HerbalDrug.SPFree.C_in.reach Diet.Add.Quercetin.C_in.reach Diet.Add.Quercetin.I.SI_in.reach Diet.Add.Quercetin.J.SI_in.reach Diet.Add.PparAgonist.SI_in.reach IC.S.Typh.4day.SB1117.C_out.reach IC.S.Typh.4day.SL1344.C_out.reach IC.S.Typh.8hr.SB1117.C_out.reach IC.S.Typh.8hr.SL1344.C_out.reach Drug.AntibioticMix.C_out.reach Diet.Fiber.AX.C_out.reach Diet.Add.Probio.BALBc.C_out.reach Diet.Add.Probio.BALBc.SI_out.reach Diet.Add.Probio.C57BL6.C_out.reach Diet.Add.Probio.C57BL6.SI_out.reach IC.Colitis.C_out.reach Diet.Fat.20.DistalSI_out.reach Diet.Fat.30.DistalSI_out.reach Diet.Fat.45.DistalSI_out.reach Diet.Fat.60.DistalSI_out.reach IC.Flagellin.C_out.reach Diet.Fiber.FOS.C_out.reach Diet.Fiber.GG.C_out.reach Diet.Add.Heme.C_out.reach IC.G.Duodelis.SI_out.reach Diet.Fiber.IN.C_out.reach Drug.HerbalDrug.C_out.reach Drug.HerbalDrug.S_out.reach Diet.Fat.20.MiddleSI_out.reach Diet.Fat.30.MiddleSI_out.reach Diet.Fat.45.MiddleSI_out.reach Drug.Penicillin.SI_out.reach Diet.Fat.20.ProximalSI_out.reach Diet.Fat.30.ProximalSI_out.reach Diet.Fat.45.ProximalSI_out.reach Diet.Fat.60.ProximalSI_out.reach Diet.Fiber.RS.C_out.reach Drug.HerbalDrug.SPFree.C_out.reach Diet.Add.Quercetin.C_out.reach Diet.Add.Quercetin.I.SI_out.reach Diet.Add.Quercetin.J.SI_out.reach Diet.Add.PparAgonist.SI_out.reach "Activation,.translocation.and.oligomerization.of.BAX" 0.023 0.002 0.003 0.003 0 0.007 0.047 0.007 0.022 0.004 0.361 0.42 0.932 0.063 0.073 0.01 0.009 0.009 Activation.and.oligomerization.of.BAK.protein 0.028 0.001 0.003 0.004 0 0.007 0.023 0.01 0.029 0.005 0.332 0.43 0.965 0.08 0.114 0.004 0.101 0.006 Release.of.apoptotic.factors.from.the.mitochondria 0.036 0.001 0.003 0.003 0.008 0 0.01 0.044 0.023 0.001 0.402 0.568 0.945 0.07 0.121 0.152 0.009 0.005 Activation.of.caspases.through.apoptosome-mediated.cleavage 0.101 0.001 0.003 0 0.007 0 0.01 0.319 0.249 0.145 0.028 0.271 Transport.and.synthesis.of.PAPS 0.002 0 0 0.002 0.004 0 0 0 0 0 0.002 0 0.001 0 0.024 0.004 0 0.004 0.008 0 0.023 0.01 0.003 0 0.535 0.001 0.005 0.003 Activation.of.the.AP-1.family.of.transcription.factors 0.01 0.056 0.004 0.004 0.074 0.002 0.026 0.006 Regulation.of.Complement.cascade 0 0 0 0.013 0.001 0 0 0.002 0 0 0.005 0.002 0 0 0 0.06 0 0 0 0.007 0.001 0 0.013 0.135 0 0 0.031 0.004 0 0.004 0 0.005 A.tetrasaccharide.linker.sequence.is.required.for.GAG.synthesis 0.007 0.001 0 0 0.003 0.001 0 0.002 0 0.002 0 0 0.003 0.002 0.004 0 0 0 0.008 0.031 0.002 0 0 0.003 0.001 0.001 0.011 0 0.024 0 0 0.021 0.006 0.002 0 0 0 0.016 Chondroitin.sulfate.biosynthesis 0.008 0 0 0.001 0 0.002 0 0 0 0.069 0.006 0 0.031 0.03 0.053 0 0.003 0 Dermatan.sulfate.biosynthesis 0.003 0.005 0 0.002 0 0.023 0.267 0.023 0.029 0.048 "Synthesis,.secretion,.and.ictivation.of.Glucose-dependent.Insulinotropic.Polypeptide.(GIP)" 0 0 0.002 0.004 0 0.122 Fibronectin.matrix.formation 0.001 0.003 0.003 0 0.01 0.01 0.065 0.003 0 0.033 Laminin.interactions 0.003 0.002 0 0.128 0.016 0 0 0 0 0 0 0 0 0 0.001 0.004 0.001 0 0.003 0.04 0 0.004 0.002 0.027 0 0.001 0 0 0 0 0 0.001 0 0 0.001 0 Integrin.cell.surface.interactions 0 0.01 0 0.003 0.002 0 0 0 0 0.002 0 0.004 0.002 0.002 0.032 0 0 0.002 0.007 0.028 Scavenging.by.Class.A.Receptors 0.005 0.007 0.004 0.197 0.112 0.048 Scavenging.by.Class.B.Receptors 0 0.001 0.001 0.011 0.68 0.01 0.012 0.002 0.009 0.001 Digestion.of.dietary.lipid 0.003 0 0 0 0 0 0.02 0.003 0 0 0 0 0 0 0.002 0.002 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 Chylomicron-mediated.lipid.transport 0 0.016 0 0.027 0 0.002 0.013 0 0.982 0 0.037 0.502 0.103 0.009 0 0.002 0.002 0 0 0 0 0 0 0.001 0.002 0 0 0 0 0 0 0 0.005 0.012 HDL-mediated.lipid.transport 0.001 0 0.008 0.007 0 0.004 0 0.011 0.032 0.06 0.052 0.006 0.045 0.059 LDL.endocytosis 0 0 0 0 0 0.001 0 0.001 0.001 0 0 0.001 0.006 0.001 0.005 0.005 Siglling.to.ERK5 0.083 0.004 0.002 0.781 Ligand-receptor.interactions 0.01 0.074 0.004 0.01 0.014 0.003 0.027 0.008 0.02 0.014 0.005 0.027 Vitamins 0.031 0.001 0.005 0 0 0.002 0.006 0.005 0.086 0 0 0.013 Detoxification.of.Reactive.Oxygen.Species 0.131 0.005 0.665 0.386 0.034 0.009 0 0.016 0.001 0.009 0.012 0 0.001 0.005 0.001 0.001 0.612 0 0.001 0.014 0.003 0.002 HSF1.activation 0.006 0.01 0.008 0 0.001 0.027 Attenuation.phase 0.005 0.007 0 0.007 0.013 0.008 Regulation.of.HSF1-mediated.heat.shock.response 0.003 0.004 0.001 0.004 0.036 0.063 Vpr-mediated.induction.of.apoptosis.by.mitochondrial.outer.membrane.permeabilization 0.032 0.002 0.001 0.006 0 0.009 0.051 0.021 0.004 0.406 0.563 0.954 0.149 0.122 0.004 0.001 Sigling.by.activated.point.mutants.of.FGFR3 0.002 0.002 0.003 0.002 0.013 0 0 0.008 0 0 0.002 0.002 0.003 0.001 0 0.005 Retinoid.metabolism.and.transport 0.004 0.001 0 0 0 0 0.126 0.014 0.006 0 0 0 0 0 0 0.001 0 0.002 0 0 0 0 0.002 0.004 0 0 0 0 0 0 0 0.156 Organic.anion.transporters 0 0 0 0.004 0.008 0 0.003 0 0.254 0 0.176 0.002 0.019 0 0.008 0.029 0.227 0.042 0.276 0 0.013 0 0 0.006 0 0 0.002 0.006 0.241 0.104 Multifunctiol.anion.exchangers 0.005 0.001 0 0.004 0.008 0.002 0 0.001 0.001 0 0.003 0 0.006 0 0.01 0.018 0.001 0 0.003 0.016 0.001 0.024 0.013 0.002 0 0.576 0 0.002 0.001 0.051 Class.II.GLUTs 0.009 0.002 Transport.of.nucleotide.sugars 0 0 0 0.001 0.002 0.004 0 0 0 0 0.001 0.006 0 0.001 0 0.009 0.012 0.001 0 0 0.001 0.027 0.059 0 0 0 0.008 0.003 0 0.002 0.004 0.025 HuR.stabilizes.mR 0.001 0.012 Dimerization.of.procaspase-8 0.001 0.817 0 0.005 0 0.003 0.001 0 0 0.275 0.004 0.221 0.995 0.01 0.043 0 0.008 0.025 Activation.of.BID.and.translocation.to.mitochondria 0 0.001 0.01 0 0.001 0.006 0.001 0.001 0.272 0.217 0.985 0.022 0.039 0.001 0.006 0.017 Pentose.phosphate.pathway.(hexose.monophosphate.shunt) 0.023 0 0.1 0.003 0.004 0.024 0.013 0.006 0.003 0 0.008 0.807 0.002 0.004 0 0.008 0 0.006 0.071 0 0.123 0.012 0.009 0.008 0 0 0 0.015 0.002 0.001 0 0 0.032 0.028 IRAK2.mediated.activation.of.TAK1.complex.upon.TLR7/8.or.9.stimulation 0.086 0.01 0.003 0 0.011 0.282 0.005 0.003 0.002 0 0 0.007 TRAF6.mediated.NF-kB.activation 0.01 0.004 0.111 0.002 0.011 0.007 0.024 0.064 0.005 0.075 0 0.358 RIP-mediated.NFkB.activation.via.ZBP1 0.009 0.002 0.001 0.012 0.69 0.009 0.09 0.036 0.06 0.001 0.007 0.003 DEx/H-box.helicases.activate.type.I.IFN.and.inflammatory.cytokines.production 0.006 0.001 0.093 0.048 Role.of.phospholipids.in.phagocytosis 0.002 0.519 0 0.004 0 0 0 0 0 0 0.022 0.001 0 0 0 0.005 0.01 0.036 0.118 0 0 0 0.008 0 0 0.007 0.007 0.054 0 0.006 FCERI.mediated.Ca+2.mobilization 0 0.03 0 0.015 0.008 0 0.01 0.165 0.005 0.037 0.012 0 0 0.009 0 0.155 0.009 0.021 0.006 0.005 0 0 0.001 0.001 0.004 0.003 0.58 0.002 0.175 0.006 Interleukin-6.sigling 0.001 0.003 0 0 0.001 0 0.028 0 0 0.002 Growth.hormone.receptor.sigling 0.001 0 0.059 0.007 0 0 0.001 0.001 0 0 0 0.014 0 0.002 0.154 0.001 0 0.001 0 0.006 0.002 0 Prolactin.receptor.sigling 0 0 0.006 0 0 0.004 0 0 0 0.092 0.003 0.088 0.007 0 0.001 0.004 0 0 Transcriptiol.activation.of.mitochondrial.biogenesis 0 0 0.001 0 0.002 0.398 0 0.004 0.006 0 0 0.001 0 0.098 0.008 0.97 0.085 0.007 0.01 0.46 0.224 0.089 0.537 0.964 0.061 0.123 Other.semaphorin.interactions 0.005 0.005 0.039 0.007 Synthesis.of.IP3.and.IP4.in.the.cytosol 0 0.75 0 0 0.001 0.003 0.003 0.07 0 0.008 0 0.001 0 0.094 0.001 0.363 0.014 0 0.003 0 0.001 0 0 0.099 0.014 0.056 IPs.transport.between.cytosol.and.ER.lumen 0 0.844 0.001 0 0 0.002 0.003 0.168 0.002 0.024 0.021 0 0.003 0 0.056 0.003 0.333 0.005 0.001 0 0.001 0 0 0 0.008 0.205 0.005 0.054 "Synthesis,.secretion,.and.deacylation.of.Ghrelin" 0.014 0.002 0.531 0.008 0.005 0 0 0 0 0.014 0 0.004 0.029 0 0 0 0.007 0.439 0.001 0.048 0.008 0 0.001 0 0.036 0 0 0.019 0 0.014 0 0 Metabolism.of.Angiotensinogen.to.Angiotensins 0 0.998 0 0 0.006 0.001 0 0.001 0.001 0.001 0.002 0.041 0.004 0.027 0.043 0.006 Synthesis.of.IPs.in.the.ER.lumen 0 0.858 0.001 0 0.001 0.001 0.003 0.172 0 0.016 0.011 0 0.003 0 0.038 0.005 0.364 0.004 0 0.001 0 0 0 0 0.007 0.186 0.005 0.05 IPs.transport.between.ER.lumen.and.cytosol 0 0.883 0.005 0 0.001 0 0.002 0.162 0 0.013 0.023 0 0.003 0 0.042 0.009 0.345 0.005 0.001 0.002 0 0 0 0.001 0.007 0.201 0.003 0.056 Activation.of.Matrix.Metalloproteises 0.004 0 0.002 0 0.002 0 0.347 0 0 0 0 0.009 0.11 0 0.016 0.006 0.003 0.004 0.005 0.016 0.012 0.098 Smooth.Muscle.Contraction 0 0.002 0.826 0 0 0.009 0.176 0.007 0.022 0 0.006 0.007 0.001 0 0.006 0.001 0 0.336 0.013 0 0.699 0.201 0.156 0 0.116 0 0.395 0.119 0.01 0.341 0.664 0.089 0.234 0.024 NFG.and.proNGF.binds.to.p75NTR 0 0.008 0 0 0.003 0.046 0.024 0.05 0.031 0.044 p75NTR.recruits.siglling.complexes 0 0.001 0.015 0.048 NF-kB.is.activated.and.sigls.survival 0.001 0.003 0.629 0.006 0.002 0.01 Pre-NOTCH.Transcription.and.Translation 0 0.005 0 0 0.012 0 0 0 0.087 0 0 0.065 0 0.004 0 0 0.001 0 0 0 0.008 0 0.004 0 Pre-NOTCH.Processing.in.the.Endoplasmic.Reticulum 0.006 0.001 0.002 0 0 0.134 0 0 0 0.064 0 0 0.03 0.014 0 0.005 0 0 0.01 0 0 0 0.004 0 0.002 0 Pre-NOTCH.Processing.in.Golgi 0.005 0.001 0 0 0 0 0 0 0.109 0 0 0.022 0.018 0 0.002 0 0 0 0 0 0.003 0.001 0.005 0.001 Sigling.by.NOTCH3 0.01 0.026 0.001 0.001 0.025 0.009 0.092 0.005 0.001 0.009 0.044 0.002 0.098 0.003 G.alpha.(s).siglling.events 0.017 0.005 0.614 0.004 0.009 0 0.001 0 0 0.027 0 0.003 0.015 0 0 0 0.007 0.667 0.006 0.034 0.096 0 0.001 0 0.028 0 0 0.005 0 0.011 0 0.006 G.beta:gamma.siglling.through.PLC.beta 0.007 0.005 0 0 0.003 0.003 0 0.004 0 0.003 0.011 0.009 0 0 0 0.007 0.4 0.062 0 0.001 0 0.016 0 0 0.004 0.006 0.775 0.042 0.003 0.014 phospho-PLA2.pathway 0.166 0.01 0 0.02 0.049 0 0 0 0.005 0.006 EGFR.Transactivation.by.Gastrin 0.003 0.031 0.152 0.016 0.006 0.008 0.005 0.007 0.006 0.001 0.044 0.007 Ca2+.pathway 0.027 0.001 0.007 0.009 0 0.005 0.002 0 0.008 0 0.002 0.017 0 0 0 0.007 0.441 0.095 0.133 0 0 0 0.018 0.001 0 0.004 0.001 0.016 0.006 0.014 Activation.of.the.pre-replicative.complex 0.008 0.004 0.003 0 0.004 0 0 0.001 0.005 0 0.057 0.012 0 0.004 D.replication.initiation 0.01 0.025 0.006 0.007 0 0.062 0.005 0.003 0.01 0.001 0.008 0 0.006 0.006 Polymerase.switching 0.01 0 0 0.004 0 0.005 Activation.of.ATR.in.response.to.replication.stress 0.005 0.005 0.002 0.101 0.041 0.057 0.002 0.005 Cyclin.D.associated.events.in.G1 0.046 0.001 0.003 0.005 0.009 0.001 0 0.002 0 0.002 0 0.001 0.002 0.001 0 0 0.022 0.196 0.182 0 0.001 0 0 0 0.001 0.069 G1/S-Specific.Transcription 0.027 0.001 0 0.016 0.002 0.001 0.002 0 0 0 0.003 0 0.001 0.01 0.08 0.006 0.019 0 0 0 PPARA.activates.gene.expression 0 0.008 0.632 0.003 0 0.002 0.064 0 0.003 0.007 0 0 0.001 0 0.041 0.038 0.003 0.989 0.018 0.008 0.001 0.506 0.263 0.248 0.309 0.885 0.221 0.046 Alpha-oxidation.of.phytate 0.007 0.001 0 0 0 0 0 0.001 0.024 0 0.02 0.001 0 0 0.001 0 0 0 0.009 0 Plasmalogen.biosynthesis 0 0.316 0.001 0.001 0.001 0.026 0 0.003 0.027 0.004 0.008 0 0.01 0 0.07 0 0.138 0.01 0 0.002 0 0.013 0 0 0 0 0.019 0.023 Telomere.Extension.By.Telomerase 0 0.002 0.027 0 0.015 0 0.003 0 0.007 0.006 0.02 0.001 0 0.001 Telomere.C-strand.synthesis.initiation 0.001 0.004 0 0.002 0 0.007 0 0.001 0.014 0.003 0 0.004 0.002 0.002 0.052 0.005 0 0.002 0.006 0.001 Meiotic.recombition 0 0.021 0.005 0 0.009 0 0.029 0.114 0.001 0.003 0.176 0.001 0.102 0 0.008 0.01 DPH.regeneration 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.001 0.002 Synthesis.of.PA 0.002 0.339 0 0.002 0.004 0.024 0 0.003 0.019 0.003 0.012 0 0 0.074 0.001 0.108 0.015 0 0.003 0 0.021 0 0 0 0 0.015 Acyl.chain.remodeling.of.DAG.and.TAG 0.008 0 0.344 0.002 0.002 0.001 0.022 0 0.004 0.029 0.002 0.021 0 0.005 0 0.085 0.074 0.001 0.1 0.01 0 0.002 0 0.015 0 0 0 0 0.022 0.013 Synthesis.of.PE 0.001 0.339 0 0.003 0.003 0.027 0 0.002 0.018 0 0.019 0 0.001 0 0.059 0.001 0.128 0.01 0 0.004 0 0.008 0 0 0 0.001 0.024 0.014 Acyl.chain.remodelling.of.PE 0.001 0.342 0.001 0 0.002 0.028 0 0.02 0.002 0.011 0 0.01 0 0.057 0 0.156 0.006 0 0.001 0 0 0 0 0 0.033 0.013 Hydrolysis.of.LPE 0 0.357 0 0.001 0.001 0.021 0 0.005 0.025 0.002 0.019 0 0.006 0 0.069 0 0.142 0.011 0.001 0 0 0.011 0 0 0 0 0.029 0.012 Synthesis.of.PC 0.008 0 0.324 0.001 0 0.001 0.02 0 0.008 0.025 0.001 0.012 0 0.007 0 0.06 0.127 0 0.102 0.011 0 0.004 0 0.007 0 0.001 0 0 0.044 0.027 PI.and.PC.transport.between.ER.and.Golgi.membranes 0.005 0 0.323 0.001 0.001 0.004 0.021 0 0.004 0.025 0 0.02 0 0.008 0 0.08 0.055 0 0.159 0.006 0 0 0 0.009 0.001 0 0 0 0.032 0.017 Acyl.chain.remodelling.of.PC 0 0.316 0 0.001 0.004 0.018 0.001 0.008 0.015 0.003 0.012 0 0.005 0 0.078 0.001 0.195 0.015 0 0 0 0.007 0.001 0 0 0 0.02 0.016 Hydrolysis.of.LPC 0.001 0.328 0.002 0 0.002 0.021 0 0.02 0 0.011 0 0 0.068 0 0.147 0.01 0.001 0.001 0 0 0 0 0 0.018 Synthesis.of.PS 0.01 0 0.349 0.002 0.006 0.001 0.024 0.001 0.003 0.023 0.003 0.018 0 0 0.084 0.064 0 0.148 0.008 0 0.003 0 0.011 0 0 0 0.001 0.018 Acyl.chain.remodelling.of.PS 0.001 0.325 0 0.002 0.003 0.017 0 0.003 0.017 0 0.012 0 0.005 0 0.066 0 0.14 0.015 0 0 0 0.013 0 0 0 0 0.03 0.019 Synthesis.of.PI 0.006 0 0.309 0.001 0 0 0.025 0 0.007 0.028 0.001 0.012 0 0 0.092 0.047 0.001 0.148 0.005 0 0.004 0 0.015 0 0 0 0 0.021 Acyl.chain.remodelling.of.PI 0.01 0 0.309 0.001 0.002 0.003 0.014 0 0.003 0.027 0 0.013 0 0 0.063 0.058 0 0.143 0.012 0 0.006 0 0.01 0 0 0 0 0.022 Synthesis.of.PG 0.007 0 0.325 0 0.001 0.002 0.029 0 0.007 0.025 0.002 0.021 0 0.007 0 0.07 0.059 0 0.132 0.009 0 0 0 0.01 0 0 0 0 0.025 0.016 Synthesis.of.CL 0.008 0 0.323 0.004 0.002 0.001 0.019 0 0.006 0.022 0.001 0.014 0 0 0.082 0.059 0.002 0.131 0.009 0 0 0 0.011 0 0 0 0 0.013 Acyl.chain.remodeling.of.CL 0.001 0.314 0 0.002 0.002 0.024 0 0.007 0.023 0.001 0.018 0 0.002 0 0.065 0 0.141 0.002 0.001 0.001 0 0.009 0 0 0 0 0.027 0.013 Synthesis.of.PIPs.at.the.ER.membrane 0.001 0.326 0.001 0 0.003 0.033 0 0.004 0.024 0.001 0.017 0 0.006 0 0.057 0 0.131 0.012 0 0.001 0 0.007 0 0 0 0 0.033 0.022 Synthesis.of.PIPs.at.the.Golgi.membrane 0 0.792 0.001 0 0.001 0 0.003 0.069 0 0.008 0 0 0 0.013 0 0.341 0.026 0 0.001 0 0 0 0 0.032 0.024 0.063 PIPs.transport.between.Golgi.and.plasma.membranes 0 0.748 0.001 0 0 0.003 0 0.101 0 0.009 0 0.004 0 0.025 0.001 0.278 0.026 0 0.002 0 0 0 0 0.03 0.023 0.067 Synthesis.of.PIPs.at.the.plasma.membrane 0 0.778 0 0 0 0.004 0.001 0.068 0 0.005 0 0 0 0.022 0 0.26 0.021 0 0 0 0.001 0 0 0.021 0.022 0.058 PIPs.transport.between.plasma.and.early.endosome.membranes 0 0.762 0 0 0 0.007 0.001 0.096 0 0.006 0 0.001 0 0.021 0 0.274 0.02 0 0 0 0 0 0 0.024 0.024 0.059 Synthesis.of.PIPs.at.the.early.endosome.membrane 0 0.763 0.001 0 0.002 0.004 0 0.088 0 0.007 0 0.001 0 0.027 0 0.288 0.023 0 0.001 0 0 0 0 0.041 0.033 0.072 PIPs.transport.between.early.endosome.and.Golgi.membranes 0.002 0.778 0 0.001 0.002 0.005 0 0.076 0 0.007 0 0.002 0 0.021 0 0.288 0.025 0 0 0 0 0 0 0.034 0.021 0.075 PIPs.transport.between.early.and.late.endosome.membranes 0.009 0 0.764 0.001 0.001 0 0.002 0.001 0.07 0 0.011 0 0 0 0.656 0.025 0 0.3 0.025 0 0 0 0.001 0 0 0.041 0.025 0.066 Synthesis.of.PIPs.at.the.late.endosome.membrane 0.001 0.77 0 0.001 0.001 0.004 0 0.094 0 0.012 0 0.003 0 0.025 0.001 0.255 0.025 0 0.001 0 0 0 0 0.032 0.018 0.078 PIPs.transport.between.late.endosome.and.Golgi.membranes 0 0.759 0 0 0 0.011 0 0.076 0 0.006 0 0.001 0 0.021 0 0.293 0.02 0 0.003 0 0.001 0 0 0.016 0.016 0.07 Synthesis.of.Leukotrienes.(LT).and.Eoxins.(EX) 0.001 0.423 0.853 0.007 0 0.005 0.426 0.153 0.002 0.002 0.195 0.214 0.228 0.006 Synthesis.of.5-eicosatetraenoic.acids 0.003 0.005 0.008 0.013 0.002 0 0.021 0.003 Synthesis.of.epoxy.(EET).and.dihydroxyeicosatrienoic.acids.(DHET) 0.003 0.006 0 0.007 0 0.015 0.024 0.001 0.007 0 Acetylcholine.regulates.insulin.secretion 0.008 0 0.796 0.008 0 0.001 0.004 0.002 0.122 0 0.011 0 0 0 0.104 0.025 0.005 0.327 0 0 0.012 0 0 0.003 0 0.14 0 0.015 Fatty.Acids.bound.to.GPR40.(FFAR1).regulate.insulin.secretion 0.01 0 0.787 0.002 0 0 0.003 0 0.111 0 0.01 0.02 0 0.001 0 0.132 0.019 0.005 0.624 0 0 0.015 0 0 0 0 0.002 0.14 0.002 0.018 Insulin.effects.increased.synthesis.of.Xylulose-5-Phosphate 0 0.32 0.002 0 0.022 0.002 0.011 0 0.008 0.036 0.003 0.023 0 0 0.031 0 0.12 0.014 0.01 0 0 0 0.011 0 0.001 0 0 0.02 PP2A-mediated.dephosphorylation.of.key.metabolic.factors 0.002 0.363 0.001 0.002 0 0.007 0 0.007 0.04 0.003 0.022 0 0.004 0 0.037 0 0.122 0.015 0 0 0 0.02 0.001 0 0 0 0.051 0.017 ChREBP.activates.metabolic.gene.expression 0.002 0.348 0 0.002 0.001 0.005 0 0.005 0.038 0.001 0.035 0 0.007 0 0.027 0.001 0.137 0.01 0 0.002 0 0.016 0 0 0 0 0.032 0.018 Fatty.acids 0.001 0.004 0.013 0.004 0.002 0.017 0.004 0.002 0.002 0.002 0.01 0.005 0.003 0.009 0.006 0.003 Eicosanoids 0.005 0.002 0.003 0.014 0.01 0.005 0.046 0.012 0.003 0.008 0.015 0.007 Electron.transport.from.DPH.to.Ferredoxin 0.001 0.017 0.002 0.008 Prostacyclin.siglling.through.prostacyclin.receptor 0.007 0.002 0.595 0.006 0.009 0 0.001 0 0.001 0.026 0 0.004 0.02 0 0 0 0.006 0.678 0.005 0.048 0.121 0 0.002 0 0.034 0 0 0.008 0.002 0.008 0.002 0.008 Elevation.of.cytosolic.Ca2+.levels 0.002 0.003 0.726 0.004 0 0.002 0.002 0.008 0 0.038 0 0.003 0 0 0 0.537 0.316 0.002 0.019 0.735 0 0.005 0 0 0.002 0 0.733 0.308 0.001 0.009 Platelet.sensitization.by.LDL 0.746 0.058 0.005 0.008 0 0 ADP.siglling.through.P2Y.purinoceptor.1 0.01 0.002 0.44 0.004 0.008 0 0 0 0.001 0.012 0 0.002 0.014 0 0 0 0.001 0.33 0 0.136 0.015 0 0 0 0.087 0 0 0.009 0.001 0.017 0.001 0.002 "BMAL1:CLOCK,NPAS2.activates.circadian.gene.expression" 0 0.005 0.64 0.007 0 0.001 0.049 0 0.001 0.007 0 0 0 0 0.044 0.046 0.002 0.989 0.014 0.008 0.001 0.486 0.255 0.239 0.304 0.882 0.224 0.043 REV-ERBA.represses.gene.expression 0 0.002 0.657 0.007 0 0.004 0.066 0 0.001 0.009 0.002 0 0 0 0 0.037 0.046 0.002 0.984 0.013 0.013 0.003 0.493 0.247 0.588 0.263 0.317 0.878 0.238 0.039 RORA.activates.circadian.gene.expression 0 0.008 0.642 0.009 0 0 0.054 0.001 0.004 0.008 0.004 0 0 0 0 0.051 0.05 0.001 0.985 0.007 0.006 0.004 0.482 0.25 0.634 0.221 0.285 0.879 0.252 0.047 RSK.activation 0.006 0.006 0.003 0 0.008 0.112 0.059 0.058 0.005 0.079 Oxidative.Stress.Induced.Senescence 0 0.366 0.009 0.013 0.075 0.071 0.001 0.031 0.009 0.039 0.003 0.001 0 0 2-LTR.circle.formation 0.006 0.002 Rev-mediated.nuclear.export.of.HIV.R 0 0.024 0 0 0 0 0.024 0 0.008 0 0 0 0.022 0.01 Vpr-mediated.nuclear.import.of.PICs 0.002 0.026 0.001 0.004 Nuclear.import.of.Rev.protein 0 0.031 0 0 0 0.002 0 0.01 0 0 0.001 0.017 CaMK.IV-mediated.phosphorylation.of.CREB 0 0.002 0.008 0 0.004 0.667 0 0.003 0.004 0.001 0 0 0 0.071 0.007 0.981 0.061 0.023 0.009 0.416 0.157 0.073 0.524 0.936 0.037 0.094 FGFR2b.ligand.binding.and.activation 0.004 0.504 0.001 0.01 0 0.002 0 0 0.004 0 0.001 0.009 0.001 0 0 0.011 0.001 0.021 0.2 0 0 0 0.014 0 0 0.023 0.503 0.067 0.002 0.056 "Ictivation,.recovery.and.regulation.of.the.phototransduction.cascade" 0.004 0.001 0.891 0.003 0 0.009 0.014 0 0 0.003 0.008 0 0.958 0.94 0.001 0.753 0.022 0.079 0 0.043 0.614 0.167 0.465 0.037 Activated.NOTCH1.Transmits.Sigl.to.the.Nucleus 0.001 0 0.01 0.003 0.008 0.008 0 0 0 0 0.014 0.008 0.011 0 0 0.007 0.38 0.003 0 0 0 0 0.005 0 Constitutive.Sigling.by.NOTCH1.HD.Domain.Mutants 0.01 0 0 0.003 0.002 0 0.007 0 0.004 0.001 0.045 0.053 0.192 0.007 0.016 0.042 Hormone.ligand-binding.receptors 0.007 0.002 0.496 0.009 0.003 0 0 0 0 0.016 0 0.009 0.01 0 0 0 0.002 0.577 0.002 0.105 0.003 0 0 0 0.095 0 0 0.021 0 0.006 0 0.003 Opsins 0.006 0.005 0.486 0.009 0.004 0 0 0 0.001 0.013 0 0.005 0.013 0 0 0 0.008 0.505 0.002 0.077 0.003 0 0 0 0.04 0 0 0.026 0 0.022 0 0 Free.fatty.acid.receptors 0.006 0.006 0.504 0.004 0.004 0 0.001 0 0 0.015 0 0.002 0.011 0 0 0 0.005 0.448 0.002 0.075 0.007 0 0.001 0 0.045 0 0 0.021 0 0.008 0 0.002 Calcitonin-like.ligand.receptors 0.006 0.003 0.633 0.008 0.01 0 0 0 0 0.017 0 0.005 0.019 0 0 0 0.008 0.64 0.004 0.031 0.089 0 0 0 0.036 0 0 0.01 0 0.007 0.006 0.004 Passive.transport.by.Aquaporins 0.004 0.005 0 0 0.001 0.002 0.001 0.001 0.01 0 0 0.002 0.004 0.001 Digestion.of.dietary.carbohydrate 0.027 0.017 0 0.006 0.01 0 Glycolysis 0.019 0.007 0.001 0.09 0.007 0.01 0.025 0.02 0.003 0.004 0 0.01 0.719 0.001 0.001 0.013 0 0.004 0 0.003 0 0.089 0 0.081 0.23 0.001 0 0 0 0 0.012 0 0 0 0 0 0.014 0.011 PRC2.methylates.histones.and.D 0.006 0.002 0.02 0 0.01 0.008 0.002 0.004 0.002 0.011 SIRT1.negatively.regulates.rR.Expression 0 0.003 0.012 0.011 0.011 0.003 0.007 0.107 0.002 0.004 0 0.009 0.003 0.014 D.methylation 0 0 0.008 0.002 0.001 0.025 0 0.001 0 0.005 0.018 0.008 0.003 0.005 0 0.001 Fructose.catabolism 0.017 0.003 0.001 0.096 0.006 0.009 0.013 0.012 0.004 0.003 0 0.009 0.709 0 0 0.017 0 0.009 0 0.004 0 0.082 0 0.074 0.235 0 0 0 0 0 0.012 0.001 0 0 0 0 0.012 0.021 Caspase-mediated.cleavage.of.cytoskeletal.proteins 0.002 0 0.041 0.003 0 0 0.003 0.031 0.011 0.004 0.066 0.173 0.104 0.024 Stimulation.of.the.cell.death.response.by.PAK-2p34 0.005 0.021 Keratan.sulfate.biosynthesis 0.002 0 0 0 0 0 0 0 0 0.008 0 0.004 0.003 0.015 0 0 0.003 0.002 0.076 0 0 0 0.017 0 0.003 0.002 Termil.pathway.of.complement 0.01 0.006 0 0 0.064 0.017 0 0.014 HS-GAG.biosynthesis 0.002 0.002 0 0 0 0.002 0.001 0 0.001 0.002 0.001 0 0.002 0 0.005 0 0 0 0.001 0.024 0.001 0 0.005 0.001 0.002 0 0.001 0 ISG15.antiviral.mechanism 0 0 0.001 0.001 0.001 0.002 0.006 0.014 Activation.of.PPARGC1A.(PGC-1alpha).by.phosphorylation 0.001 0.002 0.019 0 0.007 0.009 0.069 0.083 0.005 0.002 0.048 0.15 Mitochondrial.translation.initiation 0.005 0.001 0.004 0 0 0.019 0.008 0.002 0.01 0 0 0.01 Sema4D.mediated.inhibition.of.cell.attachment.and.migration 0 0.001 0.003 0.027 0.014 0.129 0.028 0.006 Termition.of.O-glycan.biosynthesis 0.007 0.001 0.008 0.002 0 0 0 0 0.003 0.01 0.05 0.352 0.026 0.025 0.023 0.013 0.005 0.008 Syndecan.interactions 0.002 0 0 0.001 0.001 0.01 0 0.008 0.094 0.025 0.313 0 0.073 0.251 0.05 0.068 COPI.Mediated.Transport 0.001 0 0 0 Formation.of.annular.gap.junctions 0.011 0.004 Release.of.eIF4E 0 0.01 0.001 0.004 0 0.001 0 0.042 0.002 0.122 0.018 0.049 0.001 0.004 0.004 0.001 Regulation.of.AMPK.activity.via.LKB1 0.001 0.007 0.007 0.004 0 0 0 0.044 0 0.12 0.019 0.046 0.002 0.002 0.003 0.002 Regulation.of.Rheb.GTPase.activity.by.AMPK 0 0.007 0.002 0 0.002 0 0.033 0 0.122 0.042 0.002 0.002 0.009 0.006 NRIF.sigls.cell.death.from.the.nucleus 0 0.008 0.003 0.255 0.013 0 Downregulation.of.ERBB2:ERBB3.sigling 0.007 0.008 0 0.008 0.113 0.059 0.029 0.035 Downregulation.of.ERBB4.sigling 0.009 0.006 0.741 0.221 Import.of.palmitoyl-CoA.into.the.mitochondrial.matrix 0.046 0.004 0.004 0 0.008 0.001 0.001 0 0.259 0.009 0.062 0.041 0 0.014 0.002 0 0 0 Asymmetric.localization.of.PCP.proteins 0.008 0.004 Beta.oxidation.of.palmitoyl-CoA.to.myristoyl-CoA 0.029 0.134 0.002 0.007 0.403 0 0.017 0 0 0.03 0.076 0 0.216 0.931 0.004 0.004 0 0.003 0.004 0 0 0 0 0 0 0 0.005 0.001 Beta.oxidation.of.myristoyl-CoA.to.lauroyl-CoA 0.034 0.11 0.001 0.003 0.38 0.001 0.009 0 0 0.031 0.103 0 0.932 0.004 0.003 0.002 0 0.005 0 0 0 0 0 0.005 0 0 Beta.oxidation.of.lauroyl-CoA.to.decanoyl-CoA-CoA 0.04 0.122 0.003 0.008 0.376 0.001 0.018 0 0.001 0.031 0.098 0 0.94 0.002 0.004 0 0.001 0.006 0 0 0 0 0.001 0.004 0 0.001 Beta.oxidation.of.decanoyl-CoA.to.octanoyl-CoA-CoA 0.03 0.11 0.003 0.009 0.368 0.001 0.014 0 0 0.025 0 0.931 0.006 0.004 0.002 0 0.003 0 0 0.001 0 0.008 0 0.004 Beta.oxidation.of.octanoyl-CoA.to.hexanoyl-CoA 0.027 0.107 0.002 0.007 0.388 0.002 0.018 0.001 0 0.026 0 0.918 0.005 0.001 0.006 0 0.004 0 0 0.001 0 0.006 0 0.003 Beta.oxidation.of.hexanoyl-CoA.to.butanoyl-CoA 0.033 0.113 0.002 0.012 0.387 0.002 0.012 0 0 0.027 0.001 0.941 0.006 0.009 0.003 0 0.002 0 0.001 0.002 0 0.008 0 0.002 Beta.oxidation.of.butanoyl-CoA.to.acetyl-CoA 0.042 0.133 0.002 0.005 0.422 0.001 0.016 0 0 0.015 0 0.905 0.008 0.006 0.003 0 0 0 0 0.001 0 0.008 0 0.006 mitochondrial.fatty.acid.beta-oxidation.of.unsaturated.fatty.acids 0.041 0.027 0.002 0.003 0.125 0.002 0.004 0 0 0.018 0 0.006 0.966 0 0 0 0 0 0 0 0.007 0 0 0 0.001 0 Propionyl-CoA.catabolism 0.018 0.023 0.029 0.012 0.117 0.012 0.031 0.007 0.006 0.02 0.006 0 0.001 0 0 0 0.003 0.573 0.012 0.002 Condensation.of.Prometaphase.Chromosomes 0.001 0.002 0.006 0.007 0.033 0.003 Beta-oxidation.of.very.long.chain.fatty.acids 0.005 0.02 0.006 0 0 0 0.002 0 0 0.004 0 0.02 0.007 0.004 0.002 0 0 0.001 0 0 0.006 0.001 Vitamin.D.(calciferol).metabolism 0 0.006 0 0 0.005 0.006 0.002 0.002 0.024 0 0 0.021 0.034 0.02 Acyl.chain.remodelling.of.PG 0.008 0.01 eNOS.activation 0.034 0 0 0.001 0.001 0.008 0 0 0 0.002 0.005 0 0.014 0 NOSTRIN.mediated.eNOS.trafficking 0.002 0.004 0 0.004 0.056 0.006 0.005 0.003 Regulation.of.pyruvate.dehydrogese.(PDH).complex 0.028 0.057 0.011 0.131 0.01 0.048 0.005 0.046 0.017 0 0.004 0 0 0 0 0.005 0.005 0.002 Citric.acid.cycle.(TCA.cycle) 0.103 0.032 0.001 0.018 0.139 0.038 0.047 0.005 0.079 0.007 0.001 0.105 0.003 0.003 0 0.055 0 0.001 0.002 0 0 0 0.053 0 0 0.022 Respiratory.electron.transport 0.019 0.002 0.004 0.085 0 0.001 0 0 0 0.013 0 0 0 0 0 0 0.06 0 0 0 Synthesis.and.interconversion.of.nucleotide.di-.and.triphosphates 0 0.009 0.031 0.001 0.048 0 0.006 0.116 0.006 0 0.002 0.123 Vitamin.B2.(riboflavin).metabolism 0.004 0.012 0.002 0.011 0.018 0.008 0.006 0.001 0.006 0.007 Biotin.transport.and.metabolism 0.045 0.058 0.035 0.052 0.152 0.009 0.002 0.008 0.005 0.005 Branched-chain.amino.acid.catabolism 0.041 0.014 0.001 0.037 0.004 0.249 0.003 0.008 0.026 0.003 0 0.299 0.01 0 0.002 0 0.592 0.002 CYP2E1.reactions 0 0.003 0.001 0.007 Ethanol.oxidation 0.008 0.006 0 0.004 0 0 0.004 0 0.007 0.004 0.006 0.002 0.001 0 0.001 0.003 0 0.006 "Formation.of.the.active.cofactor,.UDP-glucurote" 0.015 0.001 0 0.005 Glutathione.synthesis.and.recycling 0 0.012 0 0 0.004 0.004 0.002 0.007 0.01 0 0.002 0.007 0.005 0.001 Aflatoxin.activation.and.detoxification 0.017 0 0.003 0 L13a-mediated.translatiol.silencing.of.Ceruloplasmin.expression 0.007 0.007 0.006 0 Intrinsic.Pathway 1 0.55 0.401 0 0 0 0.203 0.005 0.003 0.004 0.021 0 0 0.001 Common.Pathway 0 0 0 0.025 0.003 0.002 Dissolution.of.Fibrin.Clot 0.237 0.027 0.005 0.069 0.036 0.008 0.015 0.01 0.002 0.024 0.002 0.004 0.054 0.006 Kinesins 0.003 0 0.005 0.002 0.006 0.004 Nephrin.interactions 0.01 0.023 0.002 0.003 Binding.and.entry.of.HIV.virion 0 0 0 0.001 0.214 0 0 0.16 0 0.782 0.895 0.003 0.11 0 0 0 0 0.003 0.002 0 0.003 0 0.009 0.006 0.004 0.004 Uncoating.of.the.HIV.Virion 0 0.014 0 0 0 0 0.003 0.023 0 0 0 0 0 0 0 0.003 Minus-strand.D.synthesis 0 0.009 0 0.003 0.001 0 0 0.038 0 0 0 0 0.001 0 0 0.008 Plus-strand.D.synthesis 0.003 0.001 0.091 0.003 0 0 0 0.005 0.001 0 Membrane.binding.and.targetting.of.GAG.proteins 0.002 0.624 0.007 0.004 0.01 0.009 Constitutive.Sigling.by.NOTCH1.PEST.Domain.Mutants 0.001 0.012 0 0.142 0.001 0.004 0.022 0.004 0 0.009 0.004 0.454 Downregulation.of.SMAD2/3:SMAD4.transcriptiol.activity 0.007 0.006 0 0.001 0.067 0.002 0.011 0.028 0.001 0.001 0.008 0.165 Formation.of.the.Early.Elongation.Complex 0.002 0 0 0 0 0 0 0 0 0 0.009 0 0.005 0.001 0 0 0.001 0 0 0 0 0 0.084 0.003 Formation.of.R.Pol.II.elongation.complex 0.001 0 0 0 0.009 0 0 0 0 0 0 0.006 0 0.004 0.001 0 0 0.054 0.002 0 0 0 0 0 0.092 0.002 Cleavage.of.Growing.Transcript.in.the.Termition.Region 0.013 0.007 0 0 0 0 0 0 0 0.002 0.01 0 0.003 0.002 0.005 0.006 0.006 0.001 0 0 0 0 0 0.006 0.223 0 0.032 0.003 pre-mR.splicing 0.005 0 0 0 0 0.002 0 0 0 0 0 0 0.005 0.008 0.041 0 0 0.136 0 0 0 0 0 0 mR.3'-end.processing 0.011 0.006 0 0 0 0 0 0 0 0.003 0 0.009 0 0.006 0.005 0.005 0.002 0 0 0 0.001 0 0.015 0 0.151 0.007 Transport.of.Mature.mR.derived.from.an.Intron-Containing.Transcript 0.011 0.007 0 0 0 0 0.001 0 0 0.002 0.009 0 0.004 0.001 0.008 0.012 0.002 0.001 0 0 0 0.001 0 0.022 0.166 0 0.113 0.005 Transport.of.the.SLBP.Dependant.Mature.mR 0.01 0.008 0 0 0 0 0.001 0.002 0 0.003 0 0.003 0.001 0.015 0.019 0.001 0 0 0 0 0.003 0 0.02 0.002 0.09 0.009 Transport.of.the.SLBP.independent.Mature.mR 0 0 0 0 0 0 0 0.001 0 0.001 0.004 0 0.001 0 0 0 0.001 0 0.027 0.001 0.07 0.013 Transport.of.Mature.mR.Derived.from.an.Intronless.Transcript 0.015 0 0 0 0 0 0.001 0 0 0 0 0 0.004 0.003 0 0 0 0 0.001 0 0.02 0.001 0.083 0.013 SLBP.Dependent.Processing.of.Replication-Dependent.Histone.Pre-mRs 0.007 0 0 0 0 0 0.001 0 0.001 0 0.001 0.001 0.015 0.001 0.004 0 0 0 0 0 0.022 0 0.045 0.006 SLBP.independent.Processing.of.Histone.Pre-mRs 0.01 0.014 0 0 0 0 0 0 0 0.003 0.008 0 0.001 0.001 0.018 0.007 0.004 0 0 0 0 0 0 0.023 0.188 0 0.053 0.006 Processing.of.Intronless.Pre-mRs 0 0 0 0 0 0 0 0.003 0 0 0.001 0.004 0 0 0 0 0 0 0.017 0.001 0.02 0.007 Formation.of.the.Editosome 0.01 0.006 0 0 0 0 0 0.001 0 0.002 0 0.004 0.002 0.013 0.004 0 0.001 0 0 0 0 0 0.013 0 0.153 0.011 Gluconeogenesis 0.057 0.182 0.004 0.026 0.194 0.165 0.009 0.195 0.002 0.001 0.06 0.763 0.002 0.008 0.029 0 0 0.007 0 0.002 0.014 0 0 0.005 Formation.of.a.pool.of.free.40S.subunits 0.011 0.008 0 0 0 0 0 0 0 0.002 0 0.003 0 0.008 0.029 0.001 0 0 0.001 0 0.002 0 0.028 0 0.039 0.007 Translation.initiation.complex.formation 0 0.002 0.01 0.003 0.008 0.013 0.025 0.011 0.003 0.016 Ribosomal.scanning.and.start.codon.recognition 0 0.003 0 0 0.004 0.001 0.004 0 0.006 0.002 0 0 0 0 0.004 0 0.01 0 0.016 0.006 GTP.hydrolysis.and.joining.of.the.60S.ribosomal.subunit 0 0.002 0.002 0 0 0.021 0.003 0 0.012 0.005 0 0.003 0.001 0 0.001 0.007 0.02 0 0.005 0.007 Glycogen.synthesis 0.018 0.004 0.251 0.001 0.011 0.007 SRP-dependent.cotranslatiol.protein.targeting.to.membrane 0.006 0.03 0.001 0.002 0.003 0.015 0.002 0.002 0.012 0.02 Peptide.chain.elongation 0 0.007 0.003 0 0.001 0.051 0 0.003 0.001 0.005 0 0 0.004 0.003 0 0.018 Eukaryotic.Translation.Termition 0.01 0.002 0.047 0.002 Glycogen.breakdown.(glycogenolysis) 0 0.438 0.141 0.028 0.535 0 0.006 0.003 0 0.009 Rap1.siglling 0 0.014 0 0 0 0 0 0.002 0 0.033 0.02 0 0.002 0.025 Ficolins.bind.to.repetitive.carbohydrate.structures.on.the.target.cell.surface 0 0.195 0.002 0 0 0 0 0.011 0 0.032 0 0.003 0.01 0 0 0 0.001 0.003 0.009 0 0 0 0.002 0 0 0.007 0.003 0 0.457 0 0.008 0 Classical.antibody-mediated.complement.activation 0 0.207 0.001 0 0 0 0 0.008 0 0.004 0.004 0.008 0 0 0 0.001 0.004 0.002 0 0 0 0.001 0 0 0.001 0 0.498 0.001 0.002 0 Altertive.complement.activation 0 0 0.255 0 0 0 0.01 0 0 0 0.001 0.001 0 0.027 0 0 0.004 0 0 0 0 0.01 0 0 0.003 0 0.006 0.001 0.468 0.108 0.019 0 0 0 0.001 0.261 0.053 0 0 0.003 0.003 0 0.42 0.001 0.002 0.989 0.386 0.002 Activation.of.C3.and.C5 0.002 0.254 0 0 0 0 0 0.013 0 0.002 0.004 0 0 0 0.002 0.007 0.008 0 0 0 0.002 0 0 0.003 0 0.002 0.007 0.002 Regulation.of.sigling.by.CBL 0.005 0.007 0.004 0 0.001 0.005 0 0.044 0.006 0.02 0.016 0.001 0.001 0.006 0 0.004 BBSome-mediated.cargo-targeting.to.cilium 0 0 0.01 0 0 0.001 0.003 0.037 0.073 0.001 0 0.025 Trafficking.of.myristoylated.proteins.to.the.cilium 0.002 0.022 0.001 0.002 0 0.001 0.007 0.016 0.001 0.005 0.019 0.01 0 0 0.018 0.008 "POU5F1.(OCT4),.SOX2,.NOG.activate.genes.related.to.proliferation" 0.001 0.004 0.296 0 0 0.01 0 0 0 0 0 0 0.01 0 0 0.003 0 0.01 0.296 0 0.001 0 0.033 0 0 0 0.004 0 0 0.004 0.067 0 0.215 0.095 Regulation.of.IGF.Activity.by.IGFBP 0 0.004 0.003 0 0.01 0.008 0 0 0.001 0 0.001 0.001 0 0.004 0.065 0.023 0.361 0.175 0.524 0.129 0.298 0.368 0.853 0.04 0.408 0.529 0.002 0.181 Collagen.biosynthesis.and.modifying.enzymes 0.002 0.004 0 0 0.01 0 0.003 0 0.001 0.002 0.027 0 0 0.031 0.001 0.029 0.009 0.005 Molecules.associated.with.elastic.fibres 0 0 0 0.007 0.002 0 0.007 0 0 0 0.001 0.009 0.028 0.014 0.039 0 Collagen.degradation 0.838 0 0.001 0.007 0.028 0.612 0 0.004 0 0.152 0.001 0.006 NRAGE.sigls.death.through.JNK 0.003 0.001 0.004 0.001 0.003 0.007 0.164 0.196 0.002 0.028 0.006 0.17 0.581 0.004 Axol.growth.inhibition.(RHOA.activation) 0.094 0 0 0 Regulated.proteolysis.of.p75NTR 0 0 0.003 0.002 NOTCH2.Activation.and.Transmission.of.Sigl.to.the.Nucleus 0.002 0.132 0.15 0.158 0.009 0.347 0 0.005 0.004 0.008 0.017 0.009 G.alpha.(i).siglling.events 0.002 0.009 0.241 0.001 0 0 0 0 0.012 0 0.002 0.005 0 0 0 0.001 0.513 0.01 0.02 0 0 0 0.001 0 0 0.005 0.002 0 0.003 0.001 Recognition.and.association.of.D.glycosylase.with.site.containing.an.affected.pyrimidine 0.007 0.003 0.004 0.007 Cleavage.of.the.damaged.pyrimidine 0.008 0.01 0.009 0.007 0.009 0.004 Depolymerisation.of.the.Nuclear.Lami 0.004 0.001 0.002 0.176 Beta-oxidation.of.pristanoyl-CoA 0.004 0 0.001 0 0.003 0 0 0.006 0.001 0.001 0.001 0 0 0.025 0 0 0.008 0.001 Synthesis.of.bile.acids.and.bile.salts.via.7alpha-hydroxycholesterol 0.004 0.007 0 0 0 0 0.001 0.007 0.01 0.032 0.001 0.005 0.053 0.013 0.02 0.024 Recycling.of.bile.acids.and.salts 0 0 0 0.012 Synthesis.of.(16-20)-hydroxyeicosatetraenoic.acids.(HETE) 0.001 0 0.001 0 Glucagon-like.Peptide-1.(GLP1).regulates.insulin.secretion 0 0.307 0 0 0 0 0.001 0 0 0 0 0 0 0.003 0.005 0.07 0 0.006 0 0 0 0.018 0.002 0.022 0.006 0.004 PKA.activation.in.glucagon.siglling 0.071 0 0.023 0.172 0 0.014 0 0.003 0 0 0 0.006 0.004 0.079 0 0.001 0.028 0.001 Vitamin.C.(ascorbate).metabolism 0 0.02 0.839 0 0.01 0.006 0.006 0.009 0.014 0.2 Platelet.Adhesion.to.exposed.collagen 0.002 0.238 0 0 0 0 0 0.003 0 0.209 0 0.029 0 0 0.01 0 0.007 0.003 0.03 0 0.001 0 0.007 0 0 0.01 0 0.01 0.021 0.003 0.069 0 ADP.siglling.through.P2Y.purinoceptor.12 0.004 0.005 0.002 0 0 0 0 0.019 0 0.003 0.017 0 0 0 0.002 0.739 0.015 0 0 0 0.019 0 0 0.003 0.002 0.002 0.008 0.006 Thromboxane.siglling.through.TP.receptor 0 0.003 0.144 0.009 0 0 0 0 0.012 0 0.003 0.017 0 0 0 0 0.201 0 0.226 0 0.001 0 0.017 0 0 0.024 0.001 0.012 0.001 0 Thrombin.siglling.through.proteise.activated.receptors.(PARs) 0.002 0 0.055 0.007 0 0 0 0 0.003 0 0.035 0.002 0.01 0 0 0 0 0.199 0 0.134 0 0 0 0.033 0 0 0.005 0.03 0 0.001 0.002 0 GPVI-mediated.activation.cascade 0 0.252 0 0 0 0 0 0.002 0 0.001 0 0 0 0.004 0.005 0.028 0 0 0 0.005 0 0 0.001 0.021 0.002 0 Vpu.mediated.degradation.of.CD4 0.029 0.004 0.021 0 0.005 0.007 Toxicity.of.botulinum.toxin.type.D.(BoNT/D) 0.092 0.001 0.004 0.013 Toxicity.of.botulinum.toxin.type.F.(BoNT/F) 0.081 0 0.004 0.005 Uptake.and.function.of.anthrax.toxins 0.009 0.001 0.047 0.001 0.07 0.002 0.409 0.007 0.024 0.998 0.002 0 0.01 0.035 0.006 0.015 FGFR1b.ligand.binding.and.activation 0.001 0.551 0 0 0.001 0.001 0 0.002 0 0.057 0.001 0 0 0 0.013 0.005 0.037 0 0.001 0 0.013 0 0 0.007 0.012 0.078 0.004 0.07 FGFR1c.ligand.binding.and.activation 0.005 0.489 0 0 0 0 0 0.002 0 0.055 0.001 0 0 0 0.004 0.002 0.043 0 0 0 0.01 0 0 0.01 0.003 0.064 0 0.055 FGFR2c.ligand.binding.and.activation 0.007 0.501 0.001 0 0 0 0.001 0.003 0 0.071 0.001 0 0 0 0.007 0.004 0.06 0 0 0 0.014 0 0 0.004 0.012 0.053 0.001 0.06 FGFR3b.ligand.binding.and.activation 0.002 0.481 0 0 0.001 0 0 0.003 0 0.062 0.001 0 0 0 0.009 0.003 0.03 0 0 0 0.006 0 0 0.01 0.008 0.059 0.001 0.05 FGFR3c.ligand.binding.and.activation 0.006 0.518 0.001 0 0.002 0 0.001 0.003 0 0 0 0 0 0.005 0.002 0.037 0 0 0 0.01 0 0 0.005 0.049 0.003 0.066 FGFR4.ligand.binding.and.activation 0.006 0.513 0.001 0 0.001 0 0 0.004 0 0.002 0 0 0 0.012 0.005 0.047 0 0 0 0.012 0 0 0.01 0.049 0.003 0.049 FGFR1c.and.Klotho.ligand.binding.and.activation 0.008 0.542 0 0 0.001 0.001 0 0.001 0 0.003 0 0 0 0.007 0.007 0.03 0 0 0 0.004 0 0 0.008 0.065 0 0.058 Activated.point.mutants.of.FGFR2 0 0.001 0 0 0.001 0 0 0.012 0.001 0.042 0 0 0 0 0 0 0 0.005 0.009 0 0.008 0 Activation.of.the.phototransduction.cascade 0 0 Downregulation.of.TGF-beta.receptor.sigling 0.004 0 0 0.009 0 0.002 0.003 0 0 0.025 0.003 0.013 TGF-beta.receptor.sigling.in.EMT.(epithelial.to.mesenchymal.transition) 0 0.004 0 0.005 0 0.016 0.001 0.017 WNT.mediated.activation.of.DVL 0.005 0.007 0.015 0.004 0.03 0.003 binding.of.TCF/LEF:CTNNB1.to.target.gene.promoters 0.01 0.238 Chemokine.receptors.bind.chemokines 0.001 0.005 0.215 0.003 0 0 0 0 0.016 0 0.005 0.006 0 0 0 0 0.477 0.006 0.015 0 0 0 0.002 0 0 0.004 0.001 0 0.007 0 Vasopressin-like.receptors 0 0.077 0.002 0 0 0 0 0 0.003 0 0 0 0 0.001 0.003 0.179 0 0.002 0 0 0 0.043 0 0.016 0.003 0.001 Formyl.peptide.receptors.bind.formyl.peptides.and.many.other.ligands 0 0.004 0.249 0 0 0 0 0 0.016 0 0.065 0.001 0.003 0 0 0 0.001 0.482 0.006 0.016 0 0 0 0.001 0 0 0.008 0.004 0.002 0.001 0.006 0.001 Relaxin.receptors 0 0.007 0.256 0.001 0 0 0 0 0.007 0 0.001 0 0 0 0 0 0.556 0.004 0.039 0 0 0 0.002 0 0 0.003 0 0 0.003 0.001 Muscarinic.acetylcholine.receptors 0 0.003 0.125 0.003 0 0 0 0 0.003 0 0.05 0.003 0.002 0 0 0 0 0.394 0.002 0.077 0 0 0 0.003 0 0 0.004 0.013 0 0 0.001 0 Adrenoceptors 0.001 0.001 0.194 0 0 0 0 0.004 0 0.047 0.005 0.004 0 0 0 0.001 0.37 0 0 0 0 0.019 0 0 0.004 0.025 0 0.003 0.001 0 Dopamine.receptors 0 0.009 0.223 0.003 0 0 0 0 0.007 0 0 0.001 0 0 0 0.001 0.551 0.007 0.036 0 0 0 0.003 0 0 0.006 0 0 0.002 0 Histamine.receptors 0.002 0.006 0.141 0.004 0 0 0 0 0.003 0 0.037 0.001 0.002 0 0 0 0 0.436 0.001 0.11 0 0 0 0.007 0 0 0.004 0.019 0 0.001 0 0 Serotonin.receptors 0 0.01 0.163 0.003 0 0 0 0.001 0.002 0 0.041 0.002 0.001 0.005 0 0 0 0 0.436 0 0.106 0 0 0 0.014 0 0 0.003 0.012 0 0.32 0 0 0 Prostanoid.ligand.receptors 0.004 0.001 0.14 0.008 0 0 0 0.001 0.003 0 0.003 0.003 0 0 0 0.001 0.351 0 0.288 0 0 0 0.033 0 0 0.028 0 0.008 0.001 0 P2Y.receptors 0 0.122 0.003 0 0 0 0 0.006 0 0.043 0.003 0.001 0.005 0 0 0 0 0.002 0.062 0 0 0 0.006 0 0 0.004 0.018 0 0.252 0.001 0 0 Adenosine.P1.receptors 0 0.002 0.235 0.001 0 0 0 0 0.005 0 0.003 0.002 0 0 0 0 0.537 0.004 0.028 0 0 0 0.002 0 0 0.008 0 0.002 0.004 0.001 Hydroxycarboxylic.acid-binding.receptors 0.003 0.007 0.225 0 0 0 0 0.001 0.011 0 0.003 0.005 0 0 0 0.001 0.48 0.006 0.018 0 0 0 0.002 0 0 0.005 0 0.002 0.004 0.003 Glucagon-type.ligand.receptors 0.007 0 0.118 0.001 0 0 0 0 0 0 0 0 0 0 0.055 0 0.001 0.213 0 0.002 0 0 0 0.033 0 0.015 0.002 0 Class.C/3.(Metabotropic.glutamate/pheromone.receptors) 0 0.006 0.165 0.003 0 0 0 0 0.002 0 0.046 0.001 0.002 0.009 0 0 0 0.001 0.419 0 0.075 0 0 0 0.005 0 0 0.001 0.015 0 0.254 0.002 0 0 Vasopressin.regulates.rel.water.homeostasis.via.Aquaporins 0 0.259 0 0 0.001 0 0.005 0 0 0.005 0 0 0 0.003 0.006 0.075 0 0.001 0 0 0 0.02 0.001 0.015 0.005 0.007 Orphan.transporters 0.002 0.085 0 0.017 0.038 0.004 0.034 0.001 0.001 0.017 0.008 0.004 0.002 0 CD28.dependent.Vav1.pathway 0.037 0.078 0.003 0.001 0.007 0.028 Antigen.activates.B.Cell.Receptor.(BCR).leading.to.generation.of.second.messengers 0 0.705 0 0 0.001 0.001 0 0 0.001 0 0.065 0.007 0.214 0.001 0 0 0.026 0.047 0.048 0.003 Endosomal/Vacuolar.pathway 0.002 0.005 0.017 0.638 0.016 0.013 0.002 0.007 The.NLRP3.inflammasome 0 0.012 0.007 0.007 0 0.945 0.226 0 0 0.063 0.152 0.196 0.007 0.002 The.IPAF.inflammasome 0 0.014 0.003 0.01 0.009 0 0.925 0.167 0 0.002 0.052 0.005 0.033 0.26 0.008 0.003 The.AIM2.inflammasome 0 0.015 0.003 0.014 0.002 0.911 0.171 0 0 0.047 0.007 0.296 0.003 0.002 Interleukin-1.processing 0 0.018 0.005 0.015 0 0.935 0.175 0 0.001 0.042 0.005 0.237 0.01 0 SEMA3A-Plexin.repulsion.sigling.by.inhibiting.Integrin.adhesion 0.046 0.003 0.01 0.009 0.002 0.005 0.006 0.154 0.02 0.004 0.009 0.032 NCAM1.interactions 0.01 0.001 0.067 0.029 Anchoring.fibril.formation 0.007 0.001 0.014 0.003 0.017 0.032 0.01 0.055 ECM.proteoglycans 0 0.006 0.01 0.003 0.004 0.007 0 0.001 0.011 0.068 0.062 0.013 0.013 0 Hormone-sensitive.lipase.(HSL)-mediated.triacylglycerol.hydrolysis 0 0 0.001 0.001 0.002 0 0 0.003 0 0.018 Regulation.of.KIT.sigling 0.01 0 0 0 0 0.001 0.014 0 0.007 0.001 0.001 0.001 Rho.GTPase.cycle 0.006 0 0 0.004 0.003 0.027 0 0.003 0.001 0.004 0.016 0.001 0.012 0.009 0.001 0.014 WNT5A-dependent.interlization.of.FZD4 0.004 0.336 0.081 0.005 "WNT5A-dependent.interlization.of.FZD2,.FZD5.and.ROR2" 0.018 0.006 RA.biosynthesis.pathway 0.007 0.994 0.317 0.005 Assembly.of.the.ORC.complex.at.the.origin.of.replication 0.011 0.01 0.035 0.001 0.008 0.001 Cohesin.Loading.onto.Chromatin 0.099 0.001 0.008 0.008 0.005 0.004 0.004 0.001 0.026 0.029 Synthesis.of.bile.acids.and.bile.salts.via.24-hydroxycholesterol 0.007 0 0 0 0 0.005 0.03 0.013 0.03 0.039 0.039 0.037 Synthesis.of.bile.acids.and.bile.salts.via.27-hydroxycholesterol 0 0 0 0 0 0.003 0.001 0.013 0 0.002 0.04 0.009 0.013 0.022 alpha-linolenic.acid.(ALA).metabolism 0 0.001 0.001 0 0 0 0.002 0.028 0.01 0.034 0.003 0 Synthesis.of.Prostaglandins.(PG).and.Thromboxanes.(TX) 0 0.007 0.001 0.102 0.001 0.038 Nicotimide.salvaging 0.003 0.006 Lysine.catabolism 0.072 0.153 0.002 0.191 0.006 0.203 0.005 0.002 0.076 0.004 0.007 0.009 0.032 0.003 0 0.002 0.033 0 0.003 0.198 Regulation.of.ornithine.decarboxylase.(ODC) 0.01 0.005 0.001 0.001 0.033 0.004 Sterols.are.12-hydroxylated.by.CYP8B1 0.005 0 0 0 0 0.002 0.002 0.028 0.003 0.001 0.012 0.004 0.006 0.014 GRB2:SOS.provides.linkage.to.MAPK.sigling.for.Integrins 0.007 0.003 0.01 0.019 0.005 0.014 p130Cas.linkage.to.MAPK.sigling.for.integrins 0.002 0.001 0.001 0 0.011 0.009 0.002 0 Tie2.Sigling 0.01 0 0.001 0.007 0.002 0.01 Sigl.regulatory.protein.(SIRP).family.interactions 0 0.003 0.009 0 0.001 0.001 0.01 0.052 0 0.029 Constitutive.Sigling.by.EGFRvIII 0.006 0.006 0 0.009 0 0.059 0.031 0 0.146 0 SHC-mediated.cascade 0.004 0.005 0.001 0.06 0.012 0.018 Sialic.acid.metabolism 0.003 0 0.022 0.068 WNT.ligand.biogenesis.and.trafficking 0.007 0.003 0.003 0.002 0.041 0.005 0.037 0.014 0 0.003 Activation.of.BAD.and.translocation.to.mitochondria 0.007 0.004 0.04 0.031 Galactose.catabolism 0.002 0.034 0.001 0.015 0.212 0.302 0 0.001 0 0 0 0.001 0 0.223 PRPP.biosynthesis 0.001 0.001 0.022 0.002 0.002 0.006 0.003 0.263 Cross-presentation.of.particulate.exogenous.antigens.(phagosomes) 0.003 0.227 0.005 0.022 0.009 0.001 IKK.complex.recruitment.mediated.by.RIP1 0.003 0.009 0 0.002 0.088 0 0.008 0.005 0.584 0 0.01 0.201 0 0.007 0.006 0.327 0.029 0.005 TRIF-mediated.programmed.cell.death 0 0.007 0 0.007 0.005 0.22 0.001 0.008 0.205 0.76 TRAF3-dependent.IRF.activation.pathway 0 0.049 0.001 0.005 0 0.105 NF-kB.activation.through.FADD/RIP-1.pathway.mediated.by.caspase-8.and.-10 0.001 0.007 0.002 0.002 0.001 0.257 0.019 0.03 TRAF6.mediated.IRF7.activation 0.4 0 0.003 0.001 0.007 0 0.011 0.007 0 0.001 0 0.03 0.029 0 Negative.regulators.of.RIG-I/MDA5.sigling 0.001 0 0.001 0.002 0.004 0 0.001 0 IRF3.mediated.activation.of.type.1.IFN 0.003 0.024 0.313 0 0.001 0.001 0.11 0.008 0.004 0 0.002 0 Mitochondrial.translation.elongation 0.002 0.003 0 0 0.031 0.003 0.001 0 Mitochondrial.translation.termition 0.007 0 0.004 0.002 Intraflagellar.transport 0.004 0.004 0.001 0 0 0.008 0 0.001 0.005 0 0.003 0.002 0.02 0.042 0 0.002 0.165 0.002 0.008 0.038 0 0.005 Sema4D.induced.cell.migration.and.growth-cone.collapse 0.008 0.019 0.006 0.005 EPHA-mediated.growth.cone.collapse 0.003 0 0.007 0.001 0 0 0.001 0.005 0.054 0.018 0 0.021 0 0.004 0 0 0 0.009 EPHB-mediated.forward.sigling 0 0.004 0 0.001 0.016 0.198 0 0 Mitochondrial.protein.import 0 0.004 0 0 0.001 0 0 0 0 0.004 XBP1(S).activates.chaperone.genes 0 0.001 0 0.004 0.001 0.126 0.434 0 0 0 G-protein.activation 0.003 0.006 0.01 0.009 0.003 0.007 0.012 0.011 Polo-like.kise.mediated.events 0.016 0 0.009 0.003 0 0 0.012 0 0.023 0.006 0 0.007 0 0.001 0.007 0.002 0 0 0.024 0.01 0.015 0 Polymerase.switching.on.the.C-strand.of.the.telomere 0.001 0 0.004 0.005 0 0.008 0.01 0.002 0.004 0 0.002 0 0.011 0 Activation.of.gene.expression.by.SREBF.(SREBP) 0 0 0 0.018 0 0.002 0 0.024 0 0.006 0 0 0 0.004 0.001 0.822 0.031 0 0 0.007 Pyrimidine.salvage.reactions 0.113 0.01 0.01 0.004 0.076 0.503 "Cobalamin.(Cbl,.vitamin.B12).transport.and.metabolism" 0.014 0.058 0.017 0.008 0.092 0.033 0.004 0.023 0.001 0.005 0.002 0.003 0.004 0.005 0.001 0 0.002 0.001 Carnitine.synthesis 0 0.007 0 0.13 Glyoxylate.metabolism 0.01 0.007 Synthesis.of.GDP-mannose 0.004 0.001 0.009 0.003 COPII.(Coat.Protein.2).Mediated.Vesicle.Transport 0.004 0.008 0.01 0 0.002 0.002 0 0.001 0 0.013 0.016 0.009 0.043 0 0.002 0.032 0 0.004 0 0.009 +-dependent.glucose.transporters 0.029 0.007 0.009 0.005 0.008 0.017 Trafficking.and.processing.of.endosomal.TLR 0.004 0 0.002 0.014 0.001 0.008 IRAK2.mediated.activation.of.TAK1.complex 0.069 0 0.008 0.001 0.011 0.035 0.001 0.198 0.756 0.854 0 0.002 0.059 0.047 0.201 0 0.009 0.226 0 0 0.003 0 TRAF6.mediated.induction.of.TAK1.complex 0.148 0.025 0 0.003 0.003 0.004 0.004 0.169 0 0.002 0 0.369 0.021 0.2 0 0.134 0.001 0 Regulation.of.actin.dymics.for.phagocytic.cup.formation 0.008 0 0.01 0.026 0.108 0 0.011 0.008 CRMPs.in.Sema3A.sigling 0.002 0 0.001 0 0.009 0.01 0 0.164 0.138 0.018 0.014 0.076 0.038 0 Ictivation.of.Cdc42.and.Rac 0.002 0.128 Activation.of.Rac 0.005 0.031 Neurofascin.interactions 0.073 0.024 0.004 0.01 HDMs.demethylate.histones 0 0.004 0.001 0.002 0 0.009 0.078 0.044 0.063 0.003 PKMTs.methylate.histone.lysines 0 0.001 0.004 0.002 0.625 0 0.008 0 0.009 0.008 0.011 0.002 0 0.029 DE.modulates.death.siglling 0.004 0 0.049 0.001 Synthesis.of.very.long-chain.fatty.acyl-CoAs 0.003 0.009 0.006 0.006 0.003 0.004 0.01 0.002 0.006 0.006 Sulfide.oxidation.to.sulfate 0.008 0.004 0.001 0.042 0.06 0.017 0.005 0 0 0.007 0.006 0.008 Aromatic.amines.can.be.N-hydroxylated.or.N-dealkylated.by.CYP1A2 0 0 DSCAM.interactions 0.01 0.109 0.244 0.003 "Biosynthesis.of.A2E,.implicated.in.retil.degradation" 0.009 0.004 0.112 0.03 The.retinoid.cycle.in.cones.(daylight.vision) 0.013 0.027 0.007 0.005 0.006 0.008 Interaction.between.L1.and.Ankyrins 0.007 0.002 0.019 0.012 G.alpha.(z).siglling.events 0.005 0.016 Synthesis.of.Lipoxins.(LX) 0.009 0.009 Adreline.siglling.through.Alpha-2.adrenergic.receptor 0.006 0.01 Senescence-Associated.Secretory.Phenotype.(SASP) 0.001 0.008 0.025 0.011 0.002 0.345 0.013 0.061 0.173 0.077 0.004 0 0.013 0 0.009 0.002 Entry.of.Influenza.Virion.into.Host.Cell.via.Endocytosis 0.006 0.008 0.024 0.126 Presyptic.function.of.Kaite.receptors 0.002 0.028 Spry.regulation.of.FGF.sigling 0 0 0 0.003 0.033 0.007 0.004 0 0 0.002 0.001 0.04 Sigling.by.FGFR1.fusion.mutants 0 0.005 0.004 0.008 0.001 0.001 0.001 0.001 0.007 0.002 Hyaluron.uptake.and.degradation 0.014 0.014 0.021 0.007 0.009 0.009 HS-GAG.degradation 0.001 0.001 0 0.004 0.001 0.016 0.007 0.016 Condensation.of.Prophase.Chromosomes 0.001 0.005 0.004 0.018 0 0 0 0.006 0.038 0.001 0 0.006 Cholesterol.biosynthesis 0.004 0 0 0 0.012 0 0 0 0 0 0.002 0 Proline.catabolism 0.01 0.004 0.008 0.005 Urea.cycle 0.077 0.538 0.218 0.01 0.001 0.007 Synthesis.of.Dolichyl-phosphate 0.014 0.002 0 0 0.058 0.013 0.009 0.001 0 0 0.009 0.002 R.Polymerase.I.Transcription.Termition 0.003 0.001 0.009 0.001 0 0.003 0.009 0.135 0.006 0.034 0 0 0.046 0.724 Antigen.processing:.Ubiquitition.&.Proteasome.degradation 0.002 0.001 0.002 0.004 0.012 0 0.007 0.013 0 0.007 0.003 0.008 0 0.031 "Antigen.Presentation:.Folding,.assembly.and.peptide.loading.of.class.I.MHC" 0 0.007 0 0.002 0.006 0 0 0.006 0 0 0.003 0.002 0 0.006 0 0.006 0 0.003 TAK1.activates.NFkB.by.phosphorylation.and.activation.of.IKKs.complex 0.009 0.101 0.005 0.103 0.001 0.002 0.299 0.006 Dopamine.Neurotransmitter.Release.Cycle 0 0.008 0.002 0 0.009 0.014 0.024 0 VxPx.cargo-targeting.to.cilium 0.007 0.006 0 0 0 0 0 0.006 0.01 0.012 0 0 0 0.004 0 0.003 DCC.mediated.attractive.sigling 0.001 0.003 0.364 0.023 0.15 0 Synthesis.of.glycosylphosphatidylinositol.(GPI) 0 0.001 0.009 0.063 0.001 0.174 0.139 0.189 0.009 0.19 Insulin.processing 0 0.002 0.001 0.233 Insulin.receptor.recycling 0.048 0.034 0 0 0.001 0.005 0.001 0 0 0 Sigling.by.BMP 0 0.006 0 0.072 0.003 0.004 0.056 0.004 Transcriptiol..activation.of..cell.cycle.inhibitor.p21 0.002 0 0.005 0.001 0 0 0 0.001 0.004 0 0.038 0.002 0 0 0 0.002 SCF(Skp2)-mediated.degradation.of.p27/p21 0.001 0 0.005 0.002 0 0 0 0.004 0.001 0 0.016 0.005 0 0 0 0.007 Recruitment.of.NuMA.to.mitotic.centrosomes 0.001 0.003 0 0.005 0.004 0.031 0.113 0.012 Golgi.Cistere.Pericentriolar.Stack.Reorganization 0.006 0.002 0.01 0 0.004 0 0.008 0.015 0.019 0 0.01 0.02 Coenzyme.A.biosynthesis 0.221 0.07 0.067 0.002 0.002 0.008 Oxygen-dependent.proline.hydroxylation.of.Hypoxia-inducible.Factor.Alpha 0.001 0.013 0 0.005 0.004 0.006 Synthesis.of.UDP-N-acetyl-glucosamine 0.009 0.02 0.004 0.004 Beta-catenin.phosphorylation.cascade 0.02 0 0 0 0.002 0 0.005 0.001 0 0.001 0.472 0.013 0.007 0.001 degradation.of.AXIN 0.022 0.006 0.014 0 0.001 0 0.01 0.004 0.009 0 0.001 0 Norepinephrine.Neurotransmitter.Release.Cycle 0 0.005 0 0 0.069 0.009 0.011 0.013 0.001 0.005 +/Cl-.dependent.neurotransmitter.transporters 0.007 0.004 0.012 0.003 Zinc.efflux.and.compartmentalization.by.the.SLC30.family 0 0.006 Serotonin.Neurotransmitter.Release.Cycle 0 0.01 0.002 0 0.067 0.011 0.019 0.018 0 0.01 Small.interfering.R.(siR).biogenesis 0.01 0.037 Post-transcriptiol.silencing.by.small.Rs 0.003 0 0.003 0.032 0.765 0.267 MHC.class.II.antigen.presentation 0 0 0 0.005 0.014 0.001 0 0 0.12 0.009 0 0 0 0 0.012 0.005 0.067 0.007 0 0.001 0.004 0 Activation.of.IRF3/IRF7.mediated.by.TBK1/IKK.epsilon 0.006 0.039 0.004 0 0.008 0.002 0.001 0.581 0 0.003 0.006 0 0.01 0.002 0.033 0.004 Interleukin.receptor.SHC.sigling 0.009 0 0.009 0 0.001 0.005 0.009 0.043 0 0.011 Recycling.pathway.of.L1 0 0.002 0.001 0 0.011 0.002 Transcriptiol.regulation.of.white.adipocyte.differentiation 0.019 0.418 0.603 0.005 0.01 0 0.004 0 0.034 0.142 Lysosome.Vesicle.Biogenesis 0 0.004 0.004 0.02 0.004 0.001 0.001 0 0.004 0.003 IRS.activation 0 0 0.073 0.013 0 0 0.007 0.009 NGF.processing 0.004 0.001 0.343 0.141 0.013 0.357 0.027 0.001 0.001 0.006 0.008 0.005 TRKA.activation.by.NGF 0.01 0 0.139 0.016 0.018 0 0.008 0.01 G.beta:gamma.siglling.through.PI3Kgamma 0.005 0.006 0.131 0.001 0 0.002 0.009 0.262 Pyrimidine.catabolism 0.263 0.005 GP1b-IX-V.activation.siglling 0.008 0.014 0.001 0.269 0.019 0.001 0.008 0 0.006 0.007 Type.I.hemidesmosome.assembly 0 0.025 0.02 0.001 0.005 0.002 0.009 0.002 0.017 0.017 RAF.activation 0.053 0.001 0.017 0 0 0.002 Adenylate.cyclase.inhibitory.pathway 0 0.008 0.001 0.01 Organic.cation.transport 0.011 0.005 0.003 0.005 Transcriptiol.regulation.by.small.Rs 0.001 0.052 0.008 0.008 SMAC.binds.to.IAPs 0 0.003 0 0.002 0.005 0.002 0.001 0.307 0.697 0.477 0.021 0.062 0.136 0.615 SMAC-mediated.dissociation.of.IAP:caspase.complexes 0.001 0.006 0.001 0.006 0.009 0 0.065 0.428 0.204 0.037 0.05 0.246 Activation.of.D.fragmentation.factor 0.008 0.064 CTLA4.inhibitory.sigling 0.006 0.039 NrCAM.interactions 0 0.008 CDO.in.myogenesis 0.023 0.006 0.041 0 0.009 0 0.005 0 S6K1.siglling 0.007 0.004 0.01 0.038 0.031 0.038 DARPP-32.events 0.113 0.01 0 0.002 0 0.002 0.01 0.242 0.001 0.004 0.004 0.002 ATM.mediated.phosphorylation.of.repair.proteins 0 0 0 0.001 0 0.001 0 0 0 0 0 0.014 Repair.synthesis.of.patch.~27-30.bases.long..by.D.polymerase 0.009 0.003 0.01 0.016 0.001 0.011 Formation.of.transcription-coupled.NER.(TC-NER).repair.complex 0.003 0.024 0 0.017 0.009 0 Dual.incision.reaction.in.TC-NER 0.02 0.009 0.001 0.01 0.009 0.002 Mismatch.repair.(MMR).directed.by.MSH2:MSH6.(MutSalpha) 0.001 0 0 0.009 0.094 0 0.004 0 0 0 0 0.002 0 0 0 0.003 Mismatch.repair.(MMR).directed.by.MSH2:MSH3.(MutSbeta) 0.001 0.1 0 0.011 0.001 0.001 0 0.006 0.001 0.001 0 0.156 Removal.of.the.Flap.Intermediate 0.004 0.005 0.002 0 0.007 0.003 0 0 Amplification..of.sigl.from.uttached..kinetochores.via.a.MAD2..inhibitory.sigl 0.004 0 0.01 0.008 0 0.001 0 0 0 0.017 0 0 0 0.002 0 0.084 0.002 0 0.059 0 0.001 0.001 0.007 0 0 0.004 Ictivation.of.APC/C.via.direct.inhibition.of.the.APC/C.complex 0.002 0.001 0.006 0.025 0 0.001 0 0 0 0 0 0.001 0.007 0 0.03 0.006 0 0.008 0 0 0 0 0 0 G2.Phase 0.004 0.001 "Activation.of.NIMA.Kises.NEK9,.NEK6,.NEK7" 0.001 0.001 0.004 0 0 0 0 0 0.002 0.006 0 0.002 0 0 Removal.of.the.Flap.Intermediate.from.the.C-strand 0.003 0.001 0.007 0.003 0.009 0.002 0.006 0.003 Sphingolipid.de.novo.biosynthesis 0 0 0.009 0 0 0.045 0.014 0.002 Basigin.interactions 0.001 0.002 0.597 0.001 0.001 0.088 0.114 0.005 0.069 0.401 Tight.junction.interactions 0.021 0.002 0.004 0.177 0.008 0.001 0.014 0.006 Oncogene.Induced.Senescence 0.003 0.005 0.005 0.014 0.056 0.507 0.242 0.001 0.001 0.461 0.051 0.345 0.006 0.003 0.003 0.004 0.014 0.043 Formation.of.the.HIV-1.Early.Elongation.Complex 0.003 0.001 0.001 0.001 0 0 0.009 0 0.004 0.001 0 0.007 0 0 0.022 0.009 Formation.of.HIV-1.elongation.complex.containing.HIV-1.Tat 0.003 0.003 0.002 0.003 0.002 0 0 0.002 0.015 0.018 0 0.067 0.008 0 0.003 0.023 Formation.of.HIV.elongation.complex.in.the.absence.of.HIV.Tat 0.003 0.005 0.002 0.002 0.004 0 0.009 0 0.001 0.006 0.008 0 0.021 0.003 0 0.055 0.001 0.01 Uncoating.of.the.Influenza.Virion 0.049 0.006 0.009 0.021 PKA.activation 0.006 0.001 0 0.002 0.005 0.007 0.006 0.001 0.011 0.032 Sigling.by.FGFR1.amplification.mutants 0.008 0.004 0.038 0.009 Constitutive.PI3K/AKT.Sigling.in.Cancer 0.019 0.018 0.008 0 0.002 0.005 NOTCH1.Intracellular.Domain.Regulates.Transcription 0.003 0.001 0 0.008 0 0 0 0.007 0 0.008 0.007 0.002 0 0.001 0 0 0 0.009 0.002 0.175 Constitutive.Sigling.by.NOTCH1.HD+PEST.Domain.Mutants 0.001 0.002 0.002 0.003 0.038 0.009 0.002 0.003 0.179 0.009 SMAD2/SMAD3:SMAD4.heterotrimer.regulates.transcription 0 0.075 0 0 0.037 0 0.017 0.001 0.009 0.002 0 0.006 0 0 0.002 0 0 0.001 0.022 0.002 degradation.of.DVL 0.011 0.041 0.01 0 0.002 0.007 negative.regulation.of.TCF-dependent.sigling.by.DVL-interacting.proteins 0.006 0.007 0.141 0.136 R.Polymerase.I.Promoter.Opening 0.025 0.011 0.026 0 0.007 0.005 0.002 0.008 0 0.005 R.Polymerase.I.Transcription.Initiation 0.037 0.008 0.038 0 0.032 0.001 0.003 0.009 0 0.003 0.002 0.003 0.005 0 R.Polymerase.II.Pre-transcription.Events 0.01 0 0 0 0 0.005 0.007 0 0 0 0 0 0 0.008 0.005 0 0.008 0 0 0.033 0.041 0 0 0 0 0 0 0.059 R.Polymerase.II.Transcription.Pre-Initiation.And.Promoter.Opening 0 0 0.005 0 0.001 0.008 0 0.01 0 0 0 0 0 0 0.004 0 0.003 0.015 0 0.008 0 0.003 0 0.017 R.Polymerase.II.Transcription.Initiation 0 0.005 0 0 0 0 0.003 0 0.071 0 0 0 0.009 0 0.044 0 0.008 0 0 0.005 0 0.003 0 0.002 0 0.023 R.Polymerase.II.Promoter.Escape 0 0.001 0 0 0 0.001 0.006 0 0.031 0 0 0 0 0.04 0.002 0.011 0 0.006 0.02 0 0 0 0.003 0 R.Pol.II.CTD.phosphorylation.and.interaction.with.CE 0 0 0 0.004 0 0.006 0 0.001 0 0 0 0 0.058 0.002 0.009 0 0.019 0 0 0 0.006 0 mR.Capping 0 0 0 0 0.005 0 0.001 0 0 0.002 0 0 0.015 0.001 0 0.026 0 0 0 0.004 0.02 0 U12.Dependent.Splicing 0 0 0.005 0.008 0.011 0 0.04 0.002 Nonsense.Mediated.Decay.(NMD).enhanced.by.the.Exon.Junction.Complex.(EJC) 0.03 0.009 0.003 0.01 0.015 0.006 MicroR.(miR).biogenesis 0.003 0.004 NoRC.negatively.regulates.rR.expression 0.001 0.653 0.005 0.009 0 0 0.006 0.127 0.006 0.005 0.033 0 0.001 0.053 FasL/.CD95L.sigling 0.001 0.812 0 0 0.006 0 0.001 0 0.245 0.008 0.388 0.06 0.169 0 0.034 0.061 TRAIL..sigling 0.03 0 0.754 0 0 0.002 0 0.001 0 0.002 0.264 0.005 0.364 0.022 0.123 0 0.025 0.011 Activation.of.RAS.in.B.cells 0.017 0 0.004 0 activated.TAK1.mediates.p38.MAPK.activation 0.083 0 0.001 0.023 0 0.003 0.003 0.002 0.071 0 0.007 0.149 NOD1/2.Sigling.Pathway 0.003 0.003 0 0.002 0.002 0.001 0.013 0.003 0.042 0.002 0.008 0 0.002 0.019 0 0.002 0.003 0.005 Interleukin-7.sigling 0.003 0 0.02 0.001 0.009 0 0 0.008 0.002 0.01 0.059 0.128 0 0.001 Anchoring.of.the.basal.body.to.the.plasma.membrane 0 0 0 0.005 0.01 0 0 0 0 0.014 HATs.acetylate.histones 0 0.01 0 0.97 0.008 0.042 0.165 0.02 0 0.002 Prefoldin.mediated.transfer.of.substrate..to.CCT/TriC 0.002 0.001 0.006 0.003 Formation.of.tubulin.folding.intermediates.by.CCT/TriC 0 0.002 0.003 0.001 Post-chaperonin.tubulin.folding.pathway 0.001 0.001 0.002 0.001 Synthesis.of.diphthamide-EEF2 0.008 0 0.002 0.003 0 0.048 0.002 0.025 0.04 0 Golgi.Associated.Vesicle.Biogenesis 0.005 0.022 0 0.003 0 0.004 0.005 0 0 0.001 SHC.activation 0 0 0.001 0 p38MAPK.events 0.006 0.009 0.204 0.306 Retrograde.neurotrophin.siglling 0 0 Sigling.by.Hippo 0.155 0.004 0.002 0.005 0.007 0.007 0.01 0.01 0.052 0.258 0.073 0.078 D.Damage.Recognition.in.GG-NER 0.001 0 0.032 0.005 0.002 0 0.008 0.005 Formation.of.incision.complex.in.GG-NER 0.042 0 0 0.007 0.004 0 0 0.06 Ubiquitin.Mediated.Degradation.of.Phosphorylated.Cdc25A 0.042 0 0.001 0.004 0 0 0 0 0.002 0 0 0.01 0.01 0 0.001 0.013 0.036 0 0.001 0.249 0.005 0.046 0.035 0.005 Chk1/Chk2(Cds1).mediated.ictivation.of.Cyclin.B:Cdk1.complex 0.039 0 0.223 0.003 0.009 0 0 0 0 0.061 0 0 0.004 0.01 0 0.009 0 0.011 0.047 0 0 0.292 0.003 0.033 0.221 0.457 G2/M.D.replication.checkpoint 0.032 0 0.16 0.001 0.009 0 0 0 0 0.018 0 0 0.008 0.004 0 0.007 0 0.018 0.084 0 0 0.349 0.009 0.089 0.416 0.424 Regulation.of.PLK1.Activity.at.G2/M.Transition 0.001 0.083 0.007 0 0.34 0.001 0.001 0 0 0.007 Loss.of.Nlp.from.mitotic.centrosomes 0.081 0.001 0 0.001 0.006 0 0.002 0 MASTL.Facilitates.Mitotic.Progression 0 0.003 0.003 0.114 Separation.of.Sister.Chromatids 0.008 0 0.007 0 0 0 0 0.005 0.018 0 0.008 0 0 0 0 0.008 Phosphorylation.of.Emi1 0.004 0 0.003 0 0 0 0 0.006 0 0.021 0 0 0 0 SCF-beta-TrCP.mediated.degradation.of.Emi1 0.012 0 0 0 0 0 0.003 0.003 0 0.013 0 0 0 0 Cdc20:Phospho-APC/C.mediated.degradation.of.Cyclin.A 0.002 0 0.023 0 0.003 0 0 0 0 0 0 0.009 0.002 0.009 0 0.002 0 0.001 0 0 0 0.003 APC/C:Cdc20.mediated.degradation.of.Cyclin.B 0.007 0 0.004 0 0.005 0 0 0 0.002 0.02 0 0.012 0 0.002 0 0 0 0.007 APC/C:Cdc20.mediated.degradation.of.Securin 0 0.003 0 0.008 0 0 0 0.001 0 0.011 0 0.014 0 0 0 0.002 Conversion.from.APC/C:Cdc20.to.APC/C:Cdh1.in.late.aphase 0 0.01 0 0.01 0 0 0 0.005 0 0.019 0 0.011 0 0 0 0.01 APC/C:Cdh1.mediated.degradation.of.Cdc20.and.other.APC/C:Cdh1.targeted.proteins.in.late.mitosis/early.G1 0 0.013 0 0 0 0 0.002 0 0.009 0 0 0 0 0.005 Autodegradation.of.Cdh1.by.Cdh1:APC/C 0.001 0.005 0.001 0.001 0.001 0.007 0.003 0.004 0.004 0.005 0.005 0.022 PKA-mediated.phosphorylation.of.key.metabolic.factors 0.005 0 0.004 0.016 0.043 0.042 0.07 0.009 AMPK.inhibits.chREBP.transcriptiol.activation.activity 0.002 0.011 0.018 0.005 Formation.of.ATP.by.chemiosmotic.coupling 0.001 0.014 0.005 0.007 0.006 0.004 Cysteine.formation.from.homocysteine 0.001 0.008 0.004 0.007 Formation.of.Senescence-Associated.Heterochromatin.Foci.(SAHF) 0 0.008 0.002 0.001 0.093 0.02 0.011 0.188 HIV.Transcription.Initiation 0.001 0.005 0.078 0 0 0.005 0.001 0.003 0.01 0.002 0 0.001 R.Polymerase.II.HIV.Promoter.Escape 0.005 0.005 0 0.002 0.005 0.003 0.003 0.001 0 0.005 Abortive.elongation.of.HIV-1.transcript.in.the.absence.of.Tat 0.003 0 0.005 0.008 0.014 0 0.017 0.013 Tat-mediated.HIV.elongation.arrest.and.recovery 0.009 0.002 0 0.006 0.019 0.005 0 0.007 Pausing.and.recovery.of.Tat-mediated.HIV.elongation 0.006 0 0.008 0.005 0.003 0.008 Uptake.and.function.of.diphtheria.toxin 0.008 0.004 0.003 0.061 0.004 0 0.007 0 0 0.03 0.014 0.095 0.005 0.009 0.002 0 0.011 0 0 0.009 EGFR.downregulation 0 0.003 0 0.001 0.005 0.002 0.007 0 0.014 0.001 Constitutive.Sigling.by.Ligand-Responsive.EGFR.Cancer.Variants 0 0 0.008 0.004 0.007 0.001 0 0.029 0.006 0.034 regulation.of.FZD.by.ubiquitition 0.004 0.005 0.081 0.209 0.079 0 0.009 0 Amino.acid.transport.across.the.plasma.membrane 0.002 0.01 0 0.011 0.002 0.003 R.Polymerase.III.Abortive.And.Retractive.Initiation 0.01 0.004 0.007 0 0 0.009 0.001 0.005 0 0 R.Polymerase.III.Transcription.Initiation.From.Type.1.Promoter 0.009 0.005 0.002 0 0.06 0.142 0.016 0.003 R.Polymerase.III.Transcription.Initiation.From.Type.3.Promoter 0 0.002 0.003 0 0.002 0.011 0.075 0.008 Phosphorylation.of.CD3.and.TCR.zeta.chains 0.005 0 0 0.001 0 0.002 0.003 0.001 0.012 0 0.036 0 0.05 0.016 Translocation.of.ZAP-70.to.Immunological.sypse 0.007 0.009 0.002 0.002 0 0 0.007 0.006 0.03 0.002 0.095 0.019 0.091 0.008 Generation.of.second.messenger.molecules 0.016 0.001 0 0 0.007 0.001 0.002 0.025 0.084 0.021 Immunoregulatory.interactions.between.a.Lymphoid.and.a.non-Lymphoid.cell 0 0.006 0 0.172 0.008 0 0.044 0 0.005 0 0.007 0.036 0.002 0 JNK.(c-Jun.kises).phosphorylation.and..activation.mediated.by.activated.human.TAK1 0.657 0.357 0.097 0.009 0.006 0.006 0.002 0 FCGR.activation 0.004 0.003 0 0 0.02 0.002 0.019 0.001 0 0 0.001 0 Interleukin-1.sigling 0.003 0.01 0.001 0.034 0.001 0.009 0 0 0.001 0.005 0 0.006 0.21 0.024 IP3.and.IP4.transport.between.cytosol.and.nucleus 0.004 0.009 Synthesis.of.IPs.in.the.nucleus 0.004 0.009 IPs.transport.between.nucleus.and.cytosol 0.007 0.006 Synthesis.of.pyrophosphates.in.the.cytosol 0.006 0.009 IP6.and.IP7.transport.between.cytosol.and.nucleus 0.004 0.008 IPs.transport.between.ER.lumen.and.nucleus 0.006 0.007 IPs.transport.between.nucleus.and.ER.lumen 0.009 0.007 G.alpha.(12/13).siglling.events 0.001 0.001 0 0 0.084 0.006 0.015 0 0.338 0.008 Adenylate.cyclase.activating.pathway 0.003 0.066 Nuclear.Pore.Complex.(NPC).Disassembly 0 0.003 0.01 0.204 0.01 0.001 0 0.015 0.029 0.006 0.012 0.026 Reversible.hydration.of.carbon.dioxide 0.001 0.006 0.002 0.007 Nef.mediated.downregulation.of.MHC.class.I.complex.cell.surface.expression 0.008 0.026 0.012 0.003 0.003 0 0.012 0.001 0.01 0.005 0.003 0.003 0.001 0.006 RAF.phosphorylates.MEK 0.145 0.016 0.037 0.269 0.002 0.001 0.006 0.006 Sodium/Proton.exchangers 0.006 0.006 CS/DS.degradation 0.002 0.01 0.001 0.044 0.041 0.051 Processing.of.D.double-strand.break.ends 0.001 0.001 0.003 0.006 0.1 0.01 0.07 0.004 Creatine.metabolism 0.004 0.004 0.011 0.004 Negative.regulation.of.the.PI3K/AKT.network 0 0.002 0.001 0.001 0.013 0.457 Release.of.Hh-Np.from.the.secreting.cell 0 0.114 Transferrin.endocytosis.and.recycling 0.002 0.039 0.009 0.001 0.007 0.013 Butyrate.Response.Factor.1.(BRF1).destabilizes.mR 0 0.008 0 0.012 0 0.486 0.041 0.003 Downstream.TCR.sigling 0.041 0 0.205 0 0.004 0.032 0.001 0.017 CD28.dependent.PI3K/Akt.sigling 0.064 0.005 0 0.239 0.001 0.006 0.045 0.008 0.008 0.008 Gamma-carboxylation.of.protein.precursors 0.002 0.028 Transport.of.gamma-carboxylated.protein.precursors.from.the.endoplasmic.reticulum.to.the.Golgi.apparatus 0.001 0.014 Removal.of.aminotermil.propeptides.from.gamma-carboxylated.proteins 0.005 0.024 Crosslinking.of.collagen.fibrils 0 0.008 0.003 0.02 VEGFR2.mediated.vascular.permeability 0 0.001 0 0.02 Metabolism.of.folate.and.pterines 0.032 0.004 R.Polymerase.III.Transcription.Initiation.From.Type.2.Promoter 0.002 0 0.051 0 R.Polymerase.III.Chain.Elongation 0.008 0 0.022 0.006 R.Polymerase.III.Transcription.Termition 0.009 0 0.039 0.002 ER-Phagosome.pathway 0.002 0.01 0.02 0.01 0.027 0.005 IRAK1.recruits.IKK.complex.upon.TLR7/8.or.9.stimulation 0.009 0.024 TRAF6.mediated.IRF7.activation.in.TLR7/8.or.9.sigling 0.008 0.008 FCERI.mediated.NF-kB.activation 0.003 0.005 0.002 0 0.005 0.008 0.002 0.005 Sigl.transduction.by.L1 0.004 0.004 EPH-ephrin.mediated.repulsion.of.cells 0.025 0.004 0 0.006 0.025 0 O-glycosylation.of.TSR.domain-containing.proteins 0.01 0.007 0.023 0.231 "SUMO.is.transferred.from.E1.to.E2.(UBE2I,.UBC9)" 0.001 0.004 0.578 0.537 0.634 0.001 Sigling.by.NOTCH4 0 0.089 0 0.009 Assembly.of.the.RAD51-ssD.nucleoprotein.complex 0.009 0.003 0.039 0.03 Dual.incision.reaction.in.GG-NER 0 0 Repair.synthesis.for.gap-filling.by.D.polymerase.in.TC-NER 0.003 0 CDT1.association.with.the.CDC6:ORC:origin.complex 0.01 0 Orc1.removal.from.chromatin 0.102 0.001 0 0.003 Unwinding.of.D 0.012 0.002 Association.of.licensing.factors.with.the.pre-replicative.complex 0.013 0.005 0.009 0 G0.and.Early.G1 0.002 0.24 0.373 0.036 0.001 0.01 Establishment.of.Sister.Chromatid.Cohesion 0 0 0 0.003 0.001 0 0 0.023 Cyclin.B2.mediated.events 0.003 0.016 Clearance.of.Nuclear.Envelope.Membranes.from.Chromatin 0.029 0.01 Resolution.of.Sister.Chromatid.Cohesion 0 0 0 0.004 0 0 0 0.013 APC-Cdc20.mediated.degradation.of.Nek2A 0.007 0.006 0 0.012 0.001 0.01 0.002 0.001 Deposition.of.new.CENPA-containing.nucleosomes.at.the.centromere 0 0 0.004 0 0 0.002 Meiotic.sypsis 0.004 0 0.002 0.002 0.019 0.003 0.004 0.008 Purine.ribonucleoside.monophosphate.biosynthesis 0 0.002 0.004 0.002 0.002 0.214 Purine.salvage 0 0 0.004 0.028 0.014 0.275 Pyrimidine.biosynthesis 0.051 0.01 0.126 0.008 0.042 0.005 Catecholamine.biosynthesis 0 0.004 0 0.072 0.039 0.039 0.005 0.005 Heme.biosynthesis 0.008 0.005 0.111 0.126 0.015 0.004 Cytosolic.iron-sulfur.cluster.assembly 0 0.011 Platelet.degranulation 0.026 0.004 0.008 0.003 Integration.of.viral.D.into.host.genomic.D 0.002 0.002 Autointegration.results.in.viral.D.circles 0.006 0.003 Budding.and.maturation.of.HIV.virion 0.029 0.006 APOBEC3G.mediated.resistance.to.HIV-1.infection 0.008 0.002 0.002 0.007 0.008 0.011 Nef.Mediated.CD4.Down-regulation 0.019 0.009 ERK1.activation 0.004 0.124 0.016 0.037 0.02 0.002 0.004 0 ERK2.activation 0.006 0.21 0.024 0.006 Zinc.influx.into.cells.by.the.SLC39.gene.family 0.009 0.012 Cytosolic.tR.aminoacylation 0.006 0.007 0.008 0.012 Deadenylation.of.mR 0.001 0.002 mR.decay.by.5'.to.3'.exoribonuclease 0.004 0.004 Regulation.by.c-FLIP 0.008 0.01 0 0.007 0.011 0 VEGF.binds.to.VEGFR.leading.to.receptor.dimerization 0.008 0.188 Autodegradation.of.the.E3.ubiquitin.ligase.COP1 0.059 0.009 Sigling.by.activated.point.mutants.of.FGFR1 0.002 0.019 0.001 0.005 Lysosphingolipid.and.LPA.receptors 0.008 0.007 Transport.of.fatty.acids 0.008 0.018 snRNP.Assembly 0.011 0.012 0.01 0.009 Role.of.Abl.in.Robo-Slit.sigling 0.003 0.027 Purine.catabolism 0.003 0.002 Regulation.of.Glucokise.by.Glucokise.Regulatory.Protein 0.012 0.01 AUF1.(hnRNP.D0).destabilizes.mR 0.022 0.002 0.01 0.007 Translocation.of.GLUT4.to.the.plasma.membrane 0.004 0.1 Activation.of.PKB 0.01 0.482 p75NTR.negatively.regulates.cell.cycle.via.SC1 0.052 0.005 Ubiquitin-dependent.degradation.of.Cyclin.D1 0.007 0.004 0.007 0.005 0.003 0.016 Regulation.of.gene.expression.by.Hypoxia-inducible.Factor 0.001 0.023 Phagosomal.maturation.(early.endosomal.stage) 0.008 0.038 Striated.Muscle.Contraction 0.005 0.025 0 0.007 Linoleic.acid.(LA).metabolism 0.004 0.001 0.005 0 Abacavir.transmembrane.transport 0.014 0.009 ABCA.transporters.in.lipid.homeostasis 0.121 0.003 Sodium/Calcium.exchangers 0.003 0.004 Histidine.catabolism 0.001 0.001 0.001 0.001 disassembly.of.the.destruction.complex.and.recruitment.of.AXIN.to.the.membrane 0.006 0.005 0.003 0.529 0.539 0 Ion.transport.by.P-type.ATPases 0.005 0.005 Regulation.of.IF.sigling 0.002 0.003 0.063 0.04 Olfactory.Sigling.Pathway 0 0 Regulation.of.the.Fanconi.anemia.pathway 0.005 0.004 0.033 0.073 Miscellaneous.substrates 0.006 0.009 0.008 0.005 Viral.RNP.Complexes.in.the.Host.Cell.Nucleus 0.001 0.002 Transport.of.nucleosides.and.free.purine.and.pyrimidine.bases.across.the.plasma.membrane 0.003 0.011 Role.of.DCC.in.regulating.apoptosis 0.144 0.001 0.008 0.011 PD-1.sigling 0.003 0 0.005 0.006 Role.of.second.messengers.in.netrin-1.sigling 0.344 0.007 RMTs.methylate.histone.arginines 0.009 0 0.006 0.042 0.01 0.177 ER.Quality.Control.Compartment.(ERQC) 0 0.001 0.005 0.022 N-Glycan.antene.elongation 0.005 0.005 "Sodium-coupled.sulphate,.di-.and.tri-carboxylate.transporters" 0.012 0.002 0.01 0.003 Packaging.Of.Telomere.Ends 0 0.029 NEP/NS2.Interacts.with.the.Cellular.Export.Machinery 0 0 PIWI-interacting.R.(piR).biogenesis 0.001 0.007 0.006 0.003 CHL1.interactions 0.01 0.004 0.089 0.025 Regulation.of.gene.expression.in.late.stage.(branching.morphogenesis).pancreatic.bud.precursor.cells 0.318 0.009 Regulation.of.sigling.by.NODAL 0.027 0.005 CREB.phosphorylation.through.the.activation.of.Adenylate.Cyclase 0.007 0.058 AKT.phosphorylates.targets.in.the.nucleus 0.01 0.069 Tachykinin.receptors.bind.tachykinins 0.045 0.006 0.004 0.034 Glutamate.Neurotransmitter.Release.Cycle 0.001 0 0.006 0.002 Acetylcholine.Neurotransmitter.Release.Cycle 0 0 0.028 0.003 GLI3.is.processed.to.GLI3R.by.the.proteasome 0.003 0.001 Glucocorticoid.biosynthesis 0.01 0.01 Mineralocorticoid.biosynthesis 0.003 0.009 Androgen.biosynthesis 0.007 0.006 Astrocytic.Glutamate-Glutamine.Uptake.And.Metabolism 0.001 0.025 0 0.006 0.003 0.001 Serotonin.and.melatonin.biosynthesis 0.009 0 0.303 0.019 Highly.calcium.permeable.postsyptic.nicotinic.acetylcholine.receptors 0.01 0.02 Depolarization.of.the.Presyptic.Termil.Triggers.the.Opening.of.Calcium.Channels 0.152 0.006 0.001 0.006 0.009 0.002 YAP1-.and.WWTR1.(TAZ)-stimulated.gene.expression 0.009 0.102 Ephrin.sigling 0.012 0.01 0.007 0.076 HDACs.deacetylate.histones 0.756 0.008 0.004 0.008 0.039 0.026 ATF6-alpha.activates.chaperone.genes 0.006 0.49 vRNP.Assembly 0.003 0.017 Apoptotic.cleavage.of.cell.adhesion..proteins 0 0 0.005 0.004 Sperm.Motility.And.Taxes 0.168 0.008 Disinhibition.of.SRE.formation 0 0 Fusion.of.the.Influenza.Virion.to.the.Host.Cell.Endosome 0.002 0.022 repression.of.WNT.target.genes 0 0.001 deactivation.of.the.beta-catenin.transactivating.complex 0.001 0 KSRP.destabilizes.mR 0.004 0.013 Attachment.of.GPI.anchor.to.uPAR 0 0 0.006 0.001 0.011 0.008 0.017 0.002 SUMO.is.proteolytically.processed 0 0.096 SUMO.is.conjugated.to.E1.(UBA2:SAE1) 0.004 0.139 Scavenging.of.heme.from.plasma 0.08 0.002 Heme.degradation 0.012 0.006 Mtb.iron.assimilation.by.chelation 0.002 0.001 0 0.001 Synthesis.of.dolichyl-phosphate.mannose 0.001 0 0.01 0.001 0.314 0.295 0.26 0.147 IRF3-mediated.induction.of.type.I.IFN 0.076 0.002 0.862 0.007 0.032 0.007 Regulation.of.IFNG.sigling 0 0 Keratan.sulfate.degradation 0.003 0.001 Glycoprotein.hormones 0.008 0.3 Ubiquinol.biosynthesis 0.003 0.089 AKT.phosphorylates.targets.in.the.cytosol 0.007 0.044 Activation.of.NF-kappaB.in.B.cells 0.01 0.008 0.486 0.034 0.092 0.004 Molybdenum.cofactor.biosynthesis 0.001 0.027 Amyloids 0.002 0.013 Bicarbote.transporters 0.019 0.007 Processing.of.D.ends.prior.to.end.rejoining 0.006 0.002 Methylation 0.491 0.01 Transport.of.organic.anions 0 0.031