This PDF file includes:

• Fig. S1. ER remodeling of the intestine through UPR^ER activation requires neuronal nonautonomous signaling.
• Fig. S2. LAMPro technology can be reliably used to quantify LDs using DHS-3::GFP.
• Fig. S3. ER remodeling is coincident with more intestinal lysosomes in neuronal xbp-1s animals.
• Fig. S4. Lipid depletion in neuronal xbp-1s is dependent on xbp-1 and ehbp-1.
• Fig. S5. Knockdown of lipophagic components does not affect chaperone induction by xbp-1s.
• Table S1. Statistics for all life-span data.
• Table S2. Organisms and strains used.
• Sequences used for cloning

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