gene_name #ID control1_Count control2_Count control3_Count suc-1_Count suc-2_Count suc-3_Count control1_FPKM control2_FPKM control3_FPKM suc-1_FPKM suc-2_FPKM suc-3_FPKM FDR log2FC regulated COG_class COG_class_annotation GO_annotation KEGG_annotation KEGG_pathway_annotation KOG_class KOG_class_annotation Pfam_annotation Swiss-Prot_annotation eggNOG_class eggNOG_class_annotation NR_annotation slc-36.4 gene2364 148 172 121 578 686 793 7.013629 8.384489 5.545389 27.67317 31.58915 37.94448 9.99180865598913e-18 2.21487101008989 up -- -- -- -- -- [E] Amino acid transport and metabolism Transmembrane amino acid transporter protein Protein H32K16.1 {ECO:0000313|EMBL:CAB10025.1} OS=Caenorhabditis elegans PE=4 SV=1 E Amino acid transport and metabolism Protein H32K16.1 [Caenorhabditis elegans] grl-9 gene35047 5094 3696 1802 233 781 439 241.2094 156.9681 77.39583 8.45036 32.40275 17.23264 0.00197485897654517 -2.87280769599064 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-9 {ECO:0000313|EMBL:CCD74346.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GRL-9 [Caenorhabditis elegans] tbcb-1 gene37952 2646 2367 1829 1042 1160 937 59.565169413 60.3927915810374 62.62766 51.2140243 51.593943 44.22109 9.47422133839819e-06 -1.13239037726443 down [D] Cell cycle control, cell division, chromosome partitioning Molecular Function: protein binding (GO:0005515);; K17262|6.13516e-166|cel:CELE_F53F4.3|F53F4.3; Protein F53F4.3; K17262 tubulin-folding cofactor B (A) -- [O] Posttranslational modification, protein turnover, chaperones CAP-Gly domain;; Ubiquitin-like domain Protein CBG11531 {ECO:0000313|EMBL:CAP30440.1} OS=Caenorhabditis briggsae PE=4 SV=1 S Function unknown Protein F53F4.3 [Caenorhabditis elegans] Y18D10A.23 gene3633 798 725 440 244 220 188 29.6963095 26.20266322885 15.959688143 9.0307587466 7.90924724280013 6.77638440041444 0.00043212960079477 -1.59933537219514 down -- -- Biological Process: amino acid transmembrane transport (GO:0003333);; -- -- [E] Amino acid transport and metabolism Transmembrane amino acid transporter protein;; Tryptophan/tyrosine permease family Protein Y18D10A.23 {ECO:0000313|EMBL:CAA22315.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein Y18D10A.23 [Caenorhabditis elegans] fat-4 gene19074 5771 5862 6119 10929 13478 18996 266.4555035394 264.470683124 275.63824908 490.2499503444 602.2059206121 864.3596131502 0.00289010950125402 1.28406577839434 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Fatty acid desaturase CRE-FAT-4 protein {ECO:0000313|EMBL:EFP04845.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein FAT-4, isoform a [Caenorhabditis elegans] F35E12.2 gene37997 28 22 30 8 5 0 8.30277582644 5.513035906537 7.12684135876 1.380697 1.31824 0.0442067 7.4567520412371e-06 -2.63444462989294 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.2, isoform a {ECO:0000313|EMBL:CAB04270.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.2, isoform a [Caenorhabditis elegans] col-40 gene4556 40722 33440 12250 2090 4773 3986 1956.792 1464.938 549.565 101.06 213.1437 181.9944 0.00391195485747002 -3.00078315070676 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Uncharacterized protein {ECO:0000313|EnsemblMetazoa:CJA03171} OS=Caenorhabditis japonica PE=4 SV=1 W Extracellular structures Protein COL-40 [Caenorhabditis elegans] tag-96 gene331 266 275 274 100 118 95 14.91219 14.82298 14.74965 6.1351 6.0030881955 5.44731 2.19687591682389e-06 -1.38805622676044 down [G] Carbohydrate transport and metabolism Molecular Function: ATP binding (GO:0005524);; Molecular Function: galactose binding (GO:0005534);; K18674|0|cel:CELE_M01D7.4|tag-96; Protein TAG-96; K18674 N-acetylgalactosamine kinase [EC:2.7.1.157] (A) -- [G] Carbohydrate transport and metabolism Galactokinase galactose-binding signature;; GHMP kinases C terminal;; GHMP kinases N terminal domain Protein TAG-96, isoform a {ECO:0000313|EMBL:CCD67952.1} OS=Caenorhabditis elegans PE=3 SV=3 R General function prediction only Protein TAG-96 [Caenorhabditis elegans] C35A5.11 gene36526 1601 1380 723 232 377 226 309.63770242875 231.77150133821 130.897671 45.494035 68.0656100019406 42.63822 0.000980812799039708 -2.15753479524594 down -- -- -- -- -- [G] Carbohydrate transport and metabolism -- Protein C35A5.11, isoform a {ECO:0000313|EMBL:CAI46564.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C35A5.11, isoform a [Caenorhabditis elegans] Y22D7AL.11 gene9797 31 50 36 76 75 104 1.34687700016 1.98271410000064 1.36113175 2.7730145546408 2.88402316 3.80305500061603 0.00586831161725568 1.11760253120767 up -- -- -- -- -- -- -- LicD family Protein Y22D7AL.11 {ECO:0000313|EMBL:CCD73752.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein Y22D7AL.11 [Caenorhabditis elegans] col-50 gene723 14255 11730 4164 696 1685 1400 483.2 384.971 138.5567 23.71944 55.2946 45.8932 0.0048006395358264 -3.0022801741348 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-50 {ECO:0000313|EMBL:CCD68366.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein COL-50 [Caenorhabditis elegans] gst-22 gene39092 71 75 108 150 176 243 9.78935 9.80395 14.3884 20.7268 23.3433 33.0836 0.00470307957937964 1.15828032148337 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-22 {ECO:0000313|EMBL:CAB07589.1} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein GST-22 [Caenorhabditis elegans] mltn-11 gene39267 82 70 47 0 19 6 2.159359 1.977224 1.237831 0.03554695226 0.48615453464 0.216897 3.26430154209539e-07 -2.99719181718722 down -- -- -- -- -- -- -- Moulting cycle Protein MLTN-11 {ECO:0000313|EMBL:CAB05642.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein MLTN-11 [Caenorhabditis elegans] ddo-2 gene35332 400 349 647 2211 2594 2848 22.64718 18.211687 36.39994 121.299 141.2906 154.6734 9.95443573661784e-27 2.44892642340044 up [E] Amino acid transport and metabolism Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00272|0|cbr:CBG04460|Hypothetical protein CBG04460; K00272 D-aspartate oxidase [EC:1.4.3.1] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Peroxisome (ko04146) [E] Amino acid transport and metabolism FAD dependent oxidoreductase CRE-DDO-2 protein {ECO:0000313|EMBL:EFP00640.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein DDO-2, isoform a [Caenorhabditis elegans] Y34F4.4 gene9620 558 533 404 244 235 227 49.83560676542 43.4465420479 33.559847285 17.9678721410498 16.89273483847 14.5131693300001 2.81462368824031e-05 -1.09065681759079 down -- -- -- -- -- -- -- Tight junction protein, Claudin-like Protein Y34F4.4 {ECO:0000313|EMBL:CCD68898.2} OS=Caenorhabditis elegans PE=4 SV=3 D Cell cycle control, cell division, chromosome partitioning Protein Y34F4.4 [Caenorhabditis elegans] F22E5.1 gene5108 1235 1244 1205 226 212 132 65.090136847 66.511566837 68.80606184 16.83747268 15.591628165387 10.074338096 1.31679785436053e-33 -2.70116881239305 down -- -- -- -- -- -- -- Protein of unknown function (DUF1647) Protein F22E5.1 {ECO:0000313|EMBL:CCD68448.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F22E5.1 [Caenorhabditis elegans] clec-82 gene13861 500 463 370 964 1179 1471 45.4551014432 47.8275343867 39.6215149913 89.6522285946 108.9766137018 112.8431186358 8.17586654280505e-06 1.43220880772909 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-82, isoform a {ECO:0000313|EMBL:CCD83494.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-82, isoform a [Caenorhabditis elegans] T05F1.9 gene2557 150 139 121 39 32 28 10.5193 9.87411 8.52998 2.82696 2.31776 2.01968 3.13097301945036e-09 -2.05906812809519 down -- -- -- -- -- -- -- -- Protein T05F1.9 {ECO:0000313|EMBL:CAB04693.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein T05F1.9 [Caenorhabditis elegans] C17H12.3 gene17794 107 181 175 73 81 63 4.996 8.262053826 8.0908990321 3.372496007 3.741701 2.8693247648 0.00478267428196088 -1.10031493755267 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain Protein C17H12.3 {ECO:0000313|EMBL:CCD64993.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17H12.3 [Caenorhabditis elegans] math-10 gene4837 3 2 3 115 110 162 0.1054622 0.209159219423 0.27884718896 6.55372 6.49466 9.98102 1.90925736084431e-23 5.5896134609245 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- MATH domain Protein MATH-10 {ECO:0000313|EMBL:CCD64677.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein MATH-10 [Caenorhabditis elegans] Y67D8B.2 gene13937 13 19 12 39 41 47 0.841763701500058 1.201787145 0.758765503371 2.5364786049 2.58956145528722 2.971053 0.00173341295709007 1.5222079107729 up -- -- Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor Protein Y67D8B.2 {ECO:0000313|EMBL:CCD73141.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein Y67D8B.2 [Caenorhabditis elegans] C13A2.5 gene35262 349 267 159 9 34 14 15.87833 12.20969 7.14291 0.510614 1.403968607 0.63995 5.65996733582501e-07 -3.77203194370976 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C13A2.5 {ECO:0000313|EMBL:CCD63107.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C13A2.5 [Caenorhabditis elegans] F32H2.11 gene2297 13 8 4 37 28 31 0.9891659173 0.6149207418 0.361255067 2.783998 2.144707 2.327802 0.000280050641467461 1.93099521031574 up -- -- -- -- -- -- -- Protein of unknown function, DUF273;; galactosyl transferase GMA12/MNN10 family Protein F32H2.11 {ECO:0000313|EMBL:CAH60774.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F32H2.11 [Caenorhabditis elegans] R05A10.4 gene22243 53 89 38 123 149 141 55.9472 82.4365 36.6537 146.453 144.35 155.784 0.000717803107545199 1.19077288847802 up -- -- -- -- -- -- -- Protein of unknown function (DUF1505) Protein CBG22343 {ECO:0000313|EMBL:CAP38962.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein R05A10.4 [Caenorhabditis elegans] slc-25A10 gene42990 2063 2079 2162 5364 5232 6479 83.1185120045102 77.9920974783955 77.4498196410412 248.241324944 235.201070787 277.518826413 8.79525706919897e-14 1.43063184350751 up -- -- -- K13577|0|cel:CELE_K11G12.5|K11G12.5; Protein K11G12.5; K13577 solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10 (A) -- [C] Energy production and conversion Mitochondrial carrier protein Protein K11G12.5 {ECO:0000313|EMBL:CCD70797.1} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein K11G12.5 [Caenorhabditis elegans] spp-18 gene18994 1606 2011 1524 620 625 953 756.6100239639 864.81000904928 673.3700131126 327.48530268468 278.0488104559 458.8320234652 1.4594206446531e-06 -1.23220312627136 down -- -- -- -- -- -- -- -- Protein SPP-18, isoform a {ECO:0000313|EMBL:CAA92462.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein SPP-18 [Caenorhabditis elegans] F49F1.7 gene14225 996 1147 996 321 234 74 103.476988562 109.78698012 96.991260013 33.6967492906 24.5574 7.955063 5.63510005378267e-25 -2.33019434030564 down -- -- -- -- -- -- -- ShK domain-like Protein F49F1.7, isoform a {ECO:0000313|EMBL:CCD66749.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49F1.7 [Caenorhabditis elegans] Y48E1B.8 gene8940 65 61 82 313 211 162 3.86001 3.752109 4.98728 19.21049 12.71837 9.61084 0.00141964823200445 1.71236936260651 up -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein Y48E1B.8 {ECO:0000313|EMBL:CAB07694.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein Y48E1B.8 [Caenorhabditis elegans] ztf-14 gene45735 147 135 85 231 228 341 3.69700843291486 3.637768494026 2.35041509506 5.31464061 5.79719110840033 8.3354599 0.00535765273486772 1.11695217467301 up [R] General function prediction only -- -- -- [R] General function prediction only Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger Protein ZTF-14 {ECO:0000313|EMBL:CAB01893.4} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown Protein ZTF-14 [Caenorhabditis elegans] T07D3.4 gene4474 311 292 259 130 137 102 16.9942579209 15.2256850397 12.8413494055 7.32896568 7.40421135164618 5.36539200056941 2.4312423948904e-05 -1.23243244012715 down -- -- -- -- -- -- -- LicD family Protein T07D3.4 {ECO:0000313|EMBL:CCD73269.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein T07D3.4 [Caenorhabditis elegans] T20D4.11 gene33918 1650 1469 716 248 287 473 124.4528 114.3861 44.19576 19.38734 19.08695 33.03723 0.00494795312510603 -1.93457778675683 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T20D4.11 {ECO:0000313|EMBL:CCD62940.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein T20D4.11 [Caenorhabditis elegans] C31C9.2 gene8957 4621 4417 3694 11938 12519 17490 297.8163 273.2373 234.2564 792.1188 778.0123 1105.131 3.23439820693992e-07 1.71333800394326 up [HE] Coenzyme transport and metabolism;; Amino acid transport and metabolism Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; K00058|0|cel:CELE_C31C9.2|C31C9.2; Protein C31C9.2; K00058 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] (A) Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain;; NAD binding domain of 6-phosphogluconate dehydrogenase;; Acetohydroxy acid isomeroreductase, catalytic domain Protein C31C9.2 {ECO:0000313|EMBL:CAB05694.1} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein C31C9.2 [Caenorhabditis elegans] Y51H7C.12 gene4671 51 57 51 17 19 27 2.972258292665 3.100298763 2.81802277606865 0.9591440591055 1.083062320226 1.5266910514031 0.00318196618133136 -1.34173582037654 down -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein Y51H7C.12, isoform a {ECO:0000313|EMBL:CCU83346.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Y51H7C.12, isoform a [Caenorhabditis elegans] dac-1 gene9556 74 83 63 169 193 234 3.66459125700709 4.05245935115157 2.57012645782158 7.11380935760011 8.15630579817503 9.71308601 6.16247922453408e-06 1.43104699675091 up -- -- -- -- -- [K] Transcription SKI/SNO/DAC family Protein DAC-1, isoform a {ECO:0000313|EMBL:CCD61864.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein DAC-1, isoform a [Caenorhabditis elegans] clec-28 gene39348 61 57 76 167 166 126 3.03613758062 2.7029008595 3.52619450258 7.860616 7.733175 5.93714248335 0.000296429315875328 1.23460682357038 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-28, isoform a {ECO:0000313|EMBL:CAB04417.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-28, isoform a [Caenorhabditis elegans] ttr-37 gene41026 91 133 60 192 258 276 13.518629621 20.28276 9.15178 30.77678 39.314619 40.91470127 0.00012090867648 1.34722195460001 up -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-37 {ECO:0000313|EMBL:CCD69803.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein TTR-37 [Caenorhabditis elegans] srr-3 gene39216 33 19 27 89 83 89 2.401629 1.393106 1.928499 6.34959 5.92222 6.35395 1.12076306590602e-05 1.71615352989298 up -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF267 Protein SRR-3 {ECO:0000313|EMBL:CAB04315.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein SRR-3 [Caenorhabditis elegans] F23F12.13 gene11151 101 101 105 184 248 224 4.04200898661 4.728860209 4.962707 9.612668776 13.9560337 13.0358 0.000577988454577693 1.08877888984475 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Sugar (and other) transporter;; Major Facilitator Superfamily Protein F23F12.13 {ECO:0000313|EMBL:CCD69932.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F23F12.13 [Caenorhabditis elegans] cut-5 gene44314 561 479 334 127 192 105 29.86782267 24.30671515 17.30011949 6.754136435 10.04155061 5.53828547 4.80975218721245e-05 -1.70459357803033 down -- -- -- -- -- -- -- Zona pellucida-like domain Protein CUT-5, isoform a {ECO:0000313|EMBL:CAA89068.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein CUT-5, isoform a [Caenorhabditis elegans] cut-1 gene8268 20843 16356 8078 841 2692 1505 853.527226 644.1229 321.4224 34.19730802 106.46539121 59.3998016 0.00018601100868366 -3.17474952012337 down -- -- -- -- -- -- -- Zona pellucida-like domain Protein CBR-CUT-1 {ECO:0000313|EMBL:CAP23673.1} OS=Caenorhabditis briggsae PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein CUT-1 [Caenorhabditis elegans] C17H12.6 gene17819 530 628 369 35 37 59 39.22663 43.43419 24.45416 2.4725123 2.40982246461356 5.895556 2.6757486581482e-13 -3.54957438948375 down -- -- -- -- -- -- -- CUB-like domain Protein C17H12.6, isoform a {ECO:0000313|EMBL:CDK13470.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only C17H12.6, isoform a [Caenorhabditis elegans] clec-73 gene14170 435 528 368 140 132 173 13.5315 16.197 11.288 4.37532 4.05405 5.34427 3.7550401574915e-09 -1.58783012780877 down -- -- -- -- -- -- -- Lectin C-type domain Protein CLEC-73 {ECO:0000313|EMBL:CCD71963.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-73 [Caenorhabditis elegans] hphd-1 gene8830 973 1053 1053 4373 5707 7626 35.67541 38.20912 37.85522 163.615 207.9391 281.67 1.38677277727073e-07 2.51802034381205 up [C] Energy production and conversion Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; K11173|0|cel:CELE_Y38F1A.6|Y38F1A.6; Protein Y38F1A.6; K11173 hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24] (A) -- [C] Energy production and conversion Iron-containing alcohol dehydrogenase;; Iron-containing alcohol dehydrogenase Putative uncharacterized protein {ECO:0000313|EMBL:EGT36044.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 C Energy production and conversion Protein Y38F1A.6 [Caenorhabditis elegans] clec-19 gene4787 308 300 92 6 39 19 16.7243 15.9233 4.96623 0.363479 2.07215 1.03994 0.00201960190697403 -3.45725602101637 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain;; UL45 protein Protein CLEC-19 {ECO:0000313|EMBL:CCD63740.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-19 [Caenorhabditis elegans] twk-28 gene42040 216 251 211 92 93 114 9.3787 10.80738 9.05947 4.08129 3.96698 4.9209 0.000127873193875344 -1.18806786657311 down [P] Inorganic ion transport and metabolism -- K05323|0|cel:CELE_C52B9.6|twk-28; Protein TWK-28; K05323 potassium channel subfamily K, invertebrate (A) -- [P] Inorganic ion transport and metabolism Ion channel;; Ion transport protein Protein TWK-28 {ECO:0000313|EMBL:CCD65414.1} OS=Caenorhabditis elegans PE=3 SV=4 K Transcription Protein TWK-28 [Caenorhabditis elegans] fbxa-69 gene38875 384 515 389 167 179 231 24.61431 32.16401 24.52623 10.88938 11.204022 14.70538 1.29205358159521e-05 -1.16500616435852 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-69 {ECO:0000313|EMBL:CAB07625.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-69 [Caenorhabditis elegans] C49G7.7 gene34130 283 340 330 158 135 157 21.0417 24.3374 23.6867 11.451 9.78925 11.4468 0.000156649387085023 -1.08994553716664 down -- -- -- -- -- -- -- -- Protein C49G7.7 {ECO:0000313|EMBL:CCD67694.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C49G7.7 [Caenorhabditis elegans] Y82E9BL.12 gene9706 40 30 24 11 11 9 1.30358276 0.9820962286 0.77714803 0.36400758 0.485598175 0.310596489 0.00258258576862206 -1.6092886603117 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein Y82E9BL.12 {ECO:0000313|EMBL:CCD73897.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y82E9BL.12 [Caenorhabditis elegans] srh-2 gene33106 14 9 20 159 195 189 0.663621717090401 0.71636616001623 0.861809887100001 7.0771226046 8.79209585030453 9.36456378316403 3.97538772830945e-24 3.65236114460359 up -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srh Protein SRH-2, isoform c {ECO:0000313|EMBL:CCD63244.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SRH-2, isoform c [Caenorhabditis elegans] pudl-1 gene13859 59 34 45 19 9 7 15.4611 8.18187 11.2689 5.12913 2.28152 2.00262 0.000141252810027541 -1.99081044375224 down -- -- -- -- -- -- -- -- Protein PUDL-1 {ECO:0000313|EMBL:CCD83531.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein PUDL-1 [Caenorhabditis elegans] M05D6.8 gene7302 478 348 548 44 51 134 7.43855 6.75583 8.79658 1.0798404 1.73465 1.728578 3.9450621903245e-10 -2.58898117644408 down -- -- -- -- -- -- -- ShK domain-like Protein M05D6.8, isoform b {ECO:0000313|EMBL:CBX53331.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein M05D6.8, isoform b [Caenorhabditis elegans] dos-3 gene9563 98 85 37 13 13 18 2.36235 2.06756 0.895062 0.318508 0.33589 0.443268 0.00489411833057308 -2.32993124930591 down -- -- -- -- -- -- -- -- Protein DOS-3 {ECO:0000313|EMBL:CCD61881.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein DOS-3 [Caenorhabditis elegans] T28A11.20 gene33867 63 62 47 7 5 7 2.73556 2.6849 2.03119 0.33184 0.239882 0.337672 2.48397390281772e-11 -3.18659330452744 down -- -- -- -- -- -- -- Peptidase family M13 Protein C17B7.10 {ECO:0000313|EMBL:CCD62957.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17B7.10 [Caenorhabditis elegans] lec-7 gene44147 55 71 39 134 164 180 9.40908 11.2606 6.37322 22.7713 26.2347 29.9542 4.61127987195828e-06 1.52751017985446 up -- -- Molecular Function: carbohydrate binding (GO:0030246);; -- -- [W] Extracellular structures Galactoside-binding lectin Galectin {ECO:0000256|RuleBase:RU102079} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein LEC-7 [Caenorhabditis elegans] F01D5.1 gene9076 2501 3545 2316 955 730 392 394.002806 530.466387060828 357.38729 161.55176 114.95292420272 69.871909 6.51740651140863e-07 -2.01940973314111 down -- -- -- -- -- -- -- ShK domain-like Protein F01D5.1 {ECO:0000313|EMBL:CAB04039.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F01D5.1 [Caenorhabditis elegans] bgnt-1.3 gene39105 28 33 34 91 72 79 1.45153 1.66961 1.71699 4.59388 3.60176 3.98705 0.000868918331437894 1.34122818217419 up -- -- -- -- -- [G] Carbohydrate transport and metabolism Glycosyl-transferase for dystroglycan Protein F21H7.10 {ECO:0000313|EMBL:CAB07595.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein F21H7.10 [Caenorhabditis elegans] T20G5.13 gene12392 84 85 44 11 8 4 9.02214 9.75157 5.190482 1.350129 0.940599 0.487169 1.03189557125519e-06 -3.22239749139405 down -- -- -- -- -- -- -- DB module Protein T20G5.13 {ECO:0000313|EMBL:CAD27184.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein T20G5.13 [Caenorhabditis elegans] cyp-29A3 gene32908 330 330 237 78 81 71 12.4877 12.3552 8.86583 2.95207 3.06356 2.7014 6.3768012819681e-12 -1.97170775221126 down -- -- Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17952|0|cel:CELE_Y38C9B.1|cyp-29A3; Protein CYP-29A3; K17952 cytochrome P450, family 29, subfamily A (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-29A3 {ECO:0000313|EMBL:CCD61789.1} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein CYP-29A3 [Caenorhabditis elegans] mks-2 gene6436 617 636 427 139 171 169 16.68258203 17.568092 11.4026119707 4.073293 4.5107763685 5.267786 8.47095554420508e-09 -1.81775117428459 down -- -- -- -- -- [S] Function unknown Predicted membrane protein Protein MKS-2 {ECO:0000313|EMBL:CCD66141.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein MKS-2 [Caenorhabditis elegans] F58G6.9 gene19016 89 95 76 579 428 260 21.81538 19.70725919 21.776719 133.8685 99.81598 75.08907 0.000469658669082672 2.27473924670373 up -- -- Molecular Function: copper ion transmembrane transporter activity (GO:0005375);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: copper ion transmembrane transport (GO:0035434);; -- -- [P] Inorganic ion transport and metabolism Ctr copper transporter family Protein F58G6.9, isoform a {ECO:0000313|EMBL:CAI59117.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein F58G6.9, isoform a [Caenorhabditis elegans] cht-1 gene41735 1042 695 1541 2736 2812 2349 32.4215 21.6606 47.9766 86.4798 87.6257 73.0337 4.22967286682934e-07 1.26138234103892 up [G] Carbohydrate transport and metabolism Cellular Component: extracellular region (GO:0005576);; Biological Process: carbohydrate metabolic process (GO:0005975);; Biological Process: chitin metabolic process (GO:0006030);; Molecular Function: chitin binding (GO:0008061);; K01183|0|cel:CELE_C04F6.3|cht-1; Protein CHT-1; K01183 chitinase [EC:3.2.1.14] (A) Amino sugar and nucleotide sugar metabolism (ko00520) [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 18;; Chitin binding Peritrophin-A domain CBN-CHT-1 protein {ECO:0000313|EMBL:EGT30253.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 I Lipid transport and metabolism Protein CHT-1 [Caenorhabditis elegans] Y71A12C.2 gene3944 3470 3219 3115 7914 7135 6370 94.24435 83.25143 82.61132 215.93025 189.9299 166.1739 1.13227300872416e-08 1.11908610957574 up [S] Function unknown -- -- -- [S] Function unknown SNARE associated Golgi protein Protein Y71A12C.2 {ECO:0000313|EMBL:CAA19559.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein Y71A12C.2 [Caenorhabditis elegans] F31F4.11 gene33082 16 13 7 36 29 43 1.055162083 0.82076263099 0.462948868 2.301097 1.87365903471 2.80567846 0.00201960190697403 1.57652734357371 up -- -- Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; -- -- -- -- Glycosyl transferase family 11 Protein F31F4.11 {ECO:0000313|EMBL:CCD70344.1} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown Protein F31F4.11 [Caenorhabditis elegans] kri-1 gene2071 98 117 82 190 163 249 2.659737 3.1491029 2.084825186 4.918599833 4.286839 6.55064 0.00242281550866174 1.01220363519838 up [R] General function prediction only Molecular Function: protein binding (GO:0005515);; K17705|0|cel:CELE_ZK265.1|kri-1; Protein KRI-1, isoform A; K17705 Krev interaction trapped protein 1 (A) -- -- -- Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; FERM central domain Protein KRI-1, isoform a {ECO:0000313|EMBL:CAB03514.2} OS=Caenorhabditis elegans PE=2 SV=1 W Extracellular structures Protein KRI-1, isoform a [Caenorhabditis elegans] elo-5 gene15431 1356 1544 1433 6276 5719 6220 133.9558 149.5021 141.8022 603.762 569.519 602.442 1.9230115150981e-27 2.06418045345819 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown ELO-5, isoform b [Caenorhabditis elegans] mltn-6 gene32965 197 151 70 8 23 2 3.90416 3.03369 1.41701 0.172613 0.471334 0.0585671 0.000211263305318749 -3.67225224723579 down -- -- -- -- -- -- -- Moulting cycle Protein MLTN-6 {ECO:0000313|EMBL:CCD74312.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein MLTN-6 [Caenorhabditis elegans] ZK596.3 gene19522 61 58 52 213 232 227 4.59439632841764 4.118281646 3.6992635482 15.062034 16.6290031534 16.84761 1.53040106066457e-10 1.96694086030065 up -- -- -- -- -- -- -- -- Protein ZK596.3 {ECO:0000313|EMBL:CAA93432.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein ZK596.3 [Caenorhabditis elegans] drd-5 gene43619 350 315 236 165 150 130 24.7616 22.84406 17.01556 11.84901 10.90736 9.41428 0.000496773473357379 -1.02659082386574 down [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase Protein F55E10.6 {ECO:0000313|EMBL:CCD70892.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein F55E10.6 [Caenorhabditis elegans] cyp-13A6 gene7787 1007 1480 1162 176 131 72 37.680178 55.85820155162 43.76290210866 6.75256250614 4.91561291382 2.73639211543 3.67589742581721e-20 -3.27702027511451 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.3|cyp-13A6; Protein CYP-13A6; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 CRE-CYP-13A6 protein {ECO:0000313|EMBL:EFP13149.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A6 [Caenorhabditis elegans] cyp-34A9 gene34103 1890 1903 1390 678 810 971 75.78944729 77.1205778 55.7707044 27.63207396 32.85698359 39.6832742 2.32103824146922e-05 -1.08260200617071 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17956|0|cbr:CBG01270|Hypothetical protein CBG01270; K17956 cytochrome P450, family 34, subfamily A (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-34A9, isoform b {ECO:0000313|EMBL:CCD61364.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CYP-34A9, isoform b [Caenorhabditis elegans] F45D11.14 gene4522 528 651 422 31 31 50 20.5732 25.8339 16.8049 1.26205 1.27232 2.03001 9.59958656218533e-21 -3.84386455104434 down -- -- -- -- -- -- -- Protein of unknown function (DUF684) Protein F45D11.14 {ECO:0000313|EMBL:CCD66368.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F45D11.14 [Caenorhabditis elegans] C27H5.6 gene6843 16 8 13 40 76 67 1.40881298 0.708818 1.10666 3.54662187886 7.36162 5.81819000001342 4.25597075325113e-05 2.3000206113473 up -- -- -- -- -- -- -- -- Protein C27H5.6 {ECO:0000313|EMBL:CCD65893.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C27H5.6 [Caenorhabditis elegans] fmo-1 gene19434 565 587 381 1145 1343 1744 20.64483 21.2291 13.77126 42.3475 50.2547 64.9087 2.06872258186627e-05 1.45813852877015 up [P] Inorganic ion transport and metabolism Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; K00485|0|cel:CELE_K08C7.2|fmo-1; Protein FMO-1; K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A) Drug metabolism - cytochrome P450 (ko00982) [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332} OS=Caenorhabditis elegans PE=2 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein FMO-1 [Caenorhabditis elegans] fat-1 gene20437 7461 7096 7624 12640 13603 18516 437.203608 412.19694 438.41675 711.425952 751.438814 1067.70143 0.000609077552014121 1.00650225517783 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; K10257|0|cel:CELE_Y67H2A.8|fat-1; Protein FAT-1; K10257 omega-3 fatty acid desaturase (delta-15 desaturase) [EC:1.14.19.-] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) -- -- Fatty acid desaturase Protein CBR-FAT-1 {ECO:0000313|EMBL:CAP22846.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein FAT-1 [Caenorhabditis elegans] ugt-31 gene411 1445 1861 1817 513 476 566 58.5043 76.25256 73.91344 21.52607 19.62959 23.38415 6.25185560991795e-17 -1.72698175435331 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-31 {ECO:0000313|EMBL:CCD69904.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein UGT-31 [Caenorhabditis elegans] T24C4.2 gene9574 509 740 889 393 306 302 43.3125532621 54.742417 61.3198948172854 20.796197 7.8278693 12.2688818 0.00517584706100143 -1.1023631714603 down -- -- -- -- -- -- -- -- Protein T24C4.2 {ECO:0000313|EMBL:CCD69956.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T24C4.2 [Caenorhabditis elegans] dod-19 gene32980 2970 4383 4044 2406 1757 1488 137.96 197.484 178.3316 105.2285 77.8287 67.1078 0.00093894541791184 -1.02069205295443 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein DOD-19 {ECO:0000313|EMBL:CCD74357.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein DOD-19 [Caenorhabditis elegans] mpc-2 gene764 929 1048 1062 2096 2356 2352 162.02222363402 158.421442 146.06534481 319.5988 356.872600000014 387.783843046 1.24704889711069e-08 1.15592232395182 up -- -- Cellular Component: mitochondrial inner membrane (GO:0005743);; Biological Process: mitochondrial pyruvate transport (GO:0006850);; -- -- [S] Function unknown Uncharacterised protein family (UPF0041) Putative uncharacterized protein {ECO:0000313|EMBL:EFP01380.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein F53F10.3 [Caenorhabditis elegans] dhs-30 gene46611 529 545 587 1132 1197 1322 33.30677 32.73032 35.3067 71.8479 73.2314 81.2165 2.87464082602281e-07 1.12938666246837 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; NADH(P)-binding;; Fungal family of unknown function (DUF1776);; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Protein DHS-30 {ECO:0000313|EMBL:CCD74455.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein DHS-30 [Caenorhabditis elegans] clec-218 gene35670 26 23 42 83 75 61 1.57176 1.38695 2.46814 4.90216 4.47153 3.64166 0.00252578669204159 1.25947850229115 up -- -- -- -- -- -- -- von Willebrand factor type A domain;; Lectin C-type domain Protein CLEC-218 {ECO:0000313|EMBL:CCD69843.1} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein CLEC-218 [Caenorhabditis elegans] F36A4.5 gene14276 66 99 75 30 36 35 10.332534 11.17078 11.92918 5.96577 4.435802 7.801099 0.00195146209181134 -1.25540811335887 down -- -- -- -- -- -- -- Caenorhabditis elegans protein of unknown function (DUF870) Protein F36A4.5, isoform a {ECO:0000313|EMBL:CCD69530.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F36A4.5 [Caenorhabditis elegans] Y105C5B.15 gene28922 4796 5457 5240 1045 827 460 234.126227575 265.39676242 259.325696099 52.36691708 40.380155473 22.522583392 2.23906122121613e-45 -2.74159089756798 down [R] General function prediction only Molecular Function: acid phosphatase activity (GO:0003993);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; -- -- [G] Carbohydrate transport and metabolism Calcineurin-like phosphoesterase;; Iron/zinc purple acid phosphatase-like protein C;; Calcineurin-like phosphoesterase superfamily domain;; PhoD-like phosphatase Purple acid phosphatase {ECO:0000256|RuleBase:RU361203} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein Y105C5B.15 [Caenorhabditis elegans] F46F5.11 gene4446 35 29 30 12 6 12 0.8636843986 0.781221696 0.774226 0.322181735 0.1642075603 0.31831922248 0.00192034624705221 -1.65601669991608 down -- -- -- -- -- -- -- Protein of unknown function, DUF288 Protein F46F5.11 {ECO:0000313|EMBL:CCD70109.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F46F5.11 [Caenorhabditis elegans] F49C12.1 gene18866 4 3 2 84 98 71 0.269914 0.2372789 0.1741776 5.3133148 6.23652 4.6332939 1.30631827809986e-21 4.8041627459062 up -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein F49C12.1 {ECO:0000313|EMBL:CAA92506.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F49C12.1 [Caenorhabditis elegans] Y39B6A.1 gene40194 9098 7423 6393 2536 2288 3666 144.8981166 107.54600211 94.012981159714 38.12932623 33.7671858697297 54.4310023900001 6.93972666772123e-07 -1.43951211570926 down -- -- -- -- -- -- -- -- Protein Y39B6A.1 {ECO:0000313|EMBL:CAC51077.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein Y39B6A.1 [Caenorhabditis elegans] irg-5 gene38005 3903 7768 3838 439 309 166 249.401 492.673 243.83 27.30819 19.54453 10.32783 5.73902788794604e-06 -4.09503530939827 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.5 {ECO:0000313|EMBL:CAB04272.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.5 [Caenorhabditis elegans] sptl-3 gene38068 1142 1143 1186 2591 2429 2087 41.710333021 40.277716433 42.2054320635 96.763225844484 87.89990233484 77.0393400001749 5.27385655976996e-07 1.02582510378351 up [H] Coenzyme transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; -- -- [O] Posttranslational modification, protein turnover, chaperones Aminotransferase class I and II Protein CBR-SPTL-3 {ECO:0000313|EMBL:CAP30518.2} OS=Caenorhabditis briggsae PE=3 SV=2 R General function prediction only Protein SPTL-3, isoform b [Caenorhabditis elegans] col-115 gene18410 396 424 410 829 851 795 17.42444 18.26254 17.71137 35.97983 36.54486 34.1287 2.51684905026618e-05 1.00124749560912 up -- -- -- -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies) Protein COL-115 {ECO:0000313|EMBL:CCD65704.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-115 [Caenorhabditis elegans] B0261.6 gene1141 99 141 167 71 77 56 29.05498 36.70414 45.52639 21.52049 20.50641 16.392444 0.00705023825706656 -1.00360346183525 down -- -- -- -- -- -- -- -- Protein B0261.6, isoform a {ECO:0000313|EMBL:CCD61574.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein B0261.6, isoform a [Caenorhabditis elegans] gst-12 gene8950 1203 1157 1222 278 202 273 198.5049 181.8309 197.1289 46.6346 34.1827 44.33662 1.10929591199421e-24 -2.2578424987276 down [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-12 {ECO:0000313|EMBL:CAB02288.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-12 [Caenorhabditis elegans] T02B11.4 gene33152 788 785 644 3473 4118 4786 89.252389 84.849507 71.7579199778 390.407100000105 447.596900098274 529.416500004518 6.41547407685754e-21 2.47414516680404 up -- -- -- -- -- -- -- -- Protein T02B11.4 {ECO:0000313|EMBL:CCD72449.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein T02B11.4 [Caenorhabditis elegans] W02B12.1 gene8334 258 278 229 114 90 102 15.60463 17.10247 13.94612 7.07556 5.555249 6.347221 8.58663457686801e-06 -1.33014167400003 down -- -- Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; -- -- [I] Lipid transport and metabolism GDSL-like Lipase/Acylhydrolase Protein W02B12.1 {ECO:0000313|EMBL:CAA91393.2} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein W02B12.1 [Caenorhabditis elegans] ptps-1 gene984 427 432 288 202 192 155 142.1780497514 131.0590306639 90.8617310727 71.4100442056 60.2327412988 51.9962274907 0.00052801694557129 -1.07183690997598 down [H] Coenzyme transport and metabolism -- K01737|2.85749e-97|cel:CELE_B0041.6|ptps-1; Protein PTPS-1, isoform B; K01737 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] (A) Folate biosynthesis (ko00790) [H] Coenzyme transport and metabolism 6-pyruvoyl tetrahydropterin synthase CBN-PTPS-1 protein {ECO:0000313|EMBL:EGT38975.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 K Transcription Protein PTPS-1, isoform a [Caenorhabditis elegans] F21C10.11 gene35987 216 236 181 60 121 133 1594.47 1644.1 1343.73 623.138 870.653 1215.91 0.00151102760906103 -1.01682534864261 down -- -- -- -- -- -- -- -- Protein F21C10.11, isoform a {ECO:0000313|EMBL:CCD61442.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein F21C10.11, isoform a [Caenorhabditis elegans] Y46G5A.38 gene8786 37 45 42 14 12 18 25.8281 28.0198 27.4228 10.9672 7.75219 13.1338 0.00210905313238016 -1.5014413089946 down -- -- -- -- -- -- -- -- Protein Y46G5A.38 {ECO:0000313|EMBL:CCE72293.1} OS=Caenorhabditis elegans PE=4 SV=1 -- -- Protein Y46G5A.38 [Caenorhabditis elegans] C54F6.18 gene35375 42 41 24 6 13 17 24.5357453161 10.9493831106 15.860649 11.8953232484003 16.9437021 21.75976487 0.00317434574843535 -1.57692026102366 down -- -- -- -- -- -- -- -- Protein C54F6.18 {ECO:0000313|EMBL:CCQ25693.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C54F6.18 [Caenorhabditis elegans] fbxa-188 gene39569 63 76 56 109 133 159 3.04679 3.5851707 2.62407 5.29702 6.3711 7.7210348 0.00424309835630232 1.03362001939327 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-188 {ECO:0000313|EMBL:CAB07207.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein FBXA-188 [Caenorhabditis elegans] bath-47 gene4721 169 191 170 326 440 560 3.12222000001742 3.764447 3.30039100118283 6.263444269 8.01074000000012 10.973157 0.000980812799039708 1.31718265129007 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- BTB/POZ domain;; MATH domain Protein BATH-46 {ECO:0000313|EMBL:CCD63704.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein BATH-47 [Caenorhabditis elegans] F45D3.3 gene37565 9293 8090 8377 2687 3398 5587 888.52470333398 729.87900251677 784.448667 252.25636303871 302.32872344269 509.246098 8.85108013995447e-06 -1.14760847623017 down -- -- -- -- -- -- -- -- Protein F45D3.3 {ECO:0000313|EMBL:CAB01502.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F45D3.3 [Caenorhabditis elegans] T06C10.3 gene18366 98 126 129 42 42 65 3.60139 4.78837 4.86208 1.62362 1.62854 2.49289 0.000593915283920628 -1.2501569235494 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein T06C10.3 {ECO:0000313|EMBL:CCD63310.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T06C10.3 [Caenorhabditis elegans] W01B6.8 gene19216 38327 35763 12286 2031 5327 4169 1729.782 1474.231 521.6593 92.5285 223.8862 180.564 0.00348114618436886 -2.91238657555626 down -- -- -- -- -- -- -- -- Protein W01B6.8 {ECO:0000313|EMBL:CAA92621.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein W01B6.8 [Caenorhabditis elegans] cyp-35B2 gene34086 83 96 49 17 27 24 3.26542 3.76384 1.94477 0.683738 1.06551 0.969515 0.00111130399027501 -1.75245075565573 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17957|0|cel:CELE_K07C6.3|cyp-35B2; Protein CYP-35B2; K17957 cytochrome P450, family 35 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-35B2 {ECO:0000313|EMBL:CCD72732.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein CYP-35B2 [Caenorhabditis elegans] Y116A8C.27 gene32449 1387 1486 1505 2915 3005 3306 131.613332 114.339083180038 129.663691898 232.233963599 252.41764 261.451169058001 8.96988600128674e-08 1.06844251644089 up [O] Posttranslational modification, protein turnover, chaperones Biological Process: proton-transporting ATP synthase complex assembly (GO:0043461);; K07556|2.82524e-174|cbr:CBG00425|Hypothetical protein CBG00425; K07556 ATP synthase mitochondrial F1 complex assembly factor 2 (A) -- [C] Energy production and conversion ATP12 chaperone protein Protein Y116A8C.27, isoform a {ECO:0000313|EMBL:CAB55134.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein Y116A8C.27, isoform a [Caenorhabditis elegans] Y47G6A.15 gene687 2041 2482 2668 1247 1114 1071 141.9521 171.6462 186.133 88.7803 78.04909 75.94288 1.26281792526856e-07 -1.07470484982455 down -- -- -- -- -- -- -- -- Protein Y47G6A.15 {ECO:0000313|EMBL:CCD72560.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y47G6A.15 [Caenorhabditis elegans] F27D9.2 gene43382 185 211 144 598 580 587 8.931907 10.422094 6.661615 29.14851 28.283372 28.13408 5.2842692751719e-12 1.70068271505056 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Major Facilitator Superfamily Protein F27D9.2 {ECO:0000313|EMBL:CCD67917.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F27D9.2 [Caenorhabditis elegans] F53C11.1 gene38019 773 910 646 448 324 321 38.6102968617 44.2164711894 31.2074260639 21.90682947661 15.8303995625 15.8188475814066 2.01391963623242e-05 -1.10042359781405 down -- -- -- -- -- -- -- CUB-like domain Protein F53C11.1, isoform a {ECO:0000313|EMBL:CAB02120.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F53C11.1 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_570 94 108 52 19 13 16 3.35782 3.83264 1.82791 0.706057 0.458933 0.587366 0.000107512355920025 -2.41289216925924 down -- -- -- -- -- [R] General function prediction only -- Protein F08F3.10 {ECO:0000313|EMBL:CCD65601.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism -- nlp-16 gene17240 648 609 442 1077 1233 1291 34.75904 31.64644 24.16378 58.576 64.6255 68.5643 1.18173003896955e-06 1.07618862920087 up -- -- -- -- -- -- -- -- Protein NLP-16, isoform a {ECO:0000313|EMBL:CCD72058.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein NLP-16 [Caenorhabditis elegans] C14C6.8 gene33034 105 104 99 11 13 2 4.475936 4.411867 4.264678 0.480575 0.543233 0.1271219502 9.82673088387276e-18 -3.57651679785294 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C14C6.8 {ECO:0000313|EMBL:CCD64464.2} OS=Caenorhabditis elegans PE=4 SV=3 K Transcription C14C6.8 [Caenorhabditis elegans] cysl-2 gene9193 6024 5699 6162 17022 15406 25943 281.0349 267.905 298.298 815.061 737.144 1226.045 0.000234773382152988 1.70019202211827 up [E] Amino acid transport and metabolism -- K01738|0|cel:CELE_K10H10.2|cysl-2; Protein CYSL-2; K01738 cysteine synthase A [EC:2.5.1.47] (A) Cysteine and methionine metabolism (ko00270);; Sulfur metabolism (ko00920);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Pyridoxal-phosphate dependent enzyme Cysteine synthase {ECO:0000256|RuleBase:RU003985} OS=Caenorhabditis elegans PE=1 SV=1 R General function prediction only Protein CYSL-2 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_477 10 5 13 32 51 69 0.677031 0.3305507 0.866826 2.046535 3.123479 4.253079 0.000549627937475022 2.43588386329408 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Eukaryotic aspartyl protease Putative uncharacterized protein {ECO:0000313|EMBL:EGT60508.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones PREDICTED: lysosomal aspartic protease-like isoform X1 [Musca domestica] catp-2 gene34391 117 122 128 40 41 44 2.133858841 2.241166 2.3459357094 0.754505462 0.76669692 0.815931369 1.16436481368858e-05 -1.56091679997622 down -- -- -- K01539|0|cel:CELE_C02E7.1|catp-2; Protein CATP-2; K01539 sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] (A) -- [P] Inorganic ion transport and metabolism E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase Protein CATP-2 {ECO:0000313|EMBL:CCD62583.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CATP-2 [Caenorhabditis elegans] F20G2.5 gene38018 577 767 391 124 95 167 27.0818 35.46881 17.78761 5.749252 4.387283 7.834501 0.00010235275205903 -2.17559863242714 down -- -- -- -- -- -- -- CUB-like domain Protein F20G2.5 {ECO:0000313|EMBL:CAB02085.4} OS=Caenorhabditis elegans PE=4 SV=4 O Posttranslational modification, protein turnover, chaperones Protein F20G2.5 [Caenorhabditis elegans] clec-65 gene8806 6208 7549 7062 2525 2580 3175 348.816 417.819 393.233 143.34 142.623 176.793 4.06180711043065e-12 -1.33682986926913 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain;; Lectin C-type domain Protein CLEC-65 {ECO:0000313|EMBL:CAB03057.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-65 [Caenorhabditis elegans] kin-5 gene19159 93 122 130 48 62 56 3.56993 4.68598 4.97991 1.92983 2.40773 2.18958 0.00450614360442619 -1.06173840494285 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein KIN-5 {ECO:0000313|EMBL:CAA93289.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein KIN-5 [Caenorhabditis elegans] K06H6.4 gene33043 29 37 37 4 3 2 1.18425 1.4672 1.46668 0.188605 0.146362 0.114995 1.5612096986901e-09 -3.52575284685034 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein K06H6.4 {ECO:0000313|EMBL:CCD64477.2} OS=Caenorhabditis elegans PE=4 SV=3 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.4 [Caenorhabditis elegans] K06H6.1 gene33049 270 237 254 27 12 7 15.4932 13.2193 14.2679 1.58115 0.674576 0.438753 2.16672095703056e-32 -4.06018029402236 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF268 Protein K06H6.1 {ECO:0000313|EMBL:CCD64472.1} OS=Caenorhabditis elegans PE=4 SV=1 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.1 [Caenorhabditis elegans] F09C8.1 gene46312 1693 1963 1277 550 595 843 87.219 98.1843 64.98353 27.65786 30.1407 41.90305 6.61648994919355e-05 -1.31782205979614 down -- -- Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; -- -- [I] Lipid transport and metabolism GDSL-like Lipase/Acylhydrolase;; GDSL-like Lipase/Acylhydrolase family Protein F09C8.1 {ECO:0000313|EMBL:CAA92221.2} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein F09C8.1 [Caenorhabditis elegans] cest-1 gene38172 372 343 346 677 878 1075 11.93047 11.08015 11.12529 22.05423 28.82155 35.39067 8.54107045365044e-05 1.30343270658308 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein T02B5.1 {ECO:0000313|EMBL:CAB03272.2} OS=Caenorhabditis elegans PE=3 SV=2 T Signal transduction mechanisms Protein T02B5.1 [Caenorhabditis elegans] col-84 gene8504 21284 16440 8424 803 2782 1353 1260.794 930.075 469.727 49.2176 157.587 76.6825 0.000117134361191181 -3.23122139008791 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-84 {ECO:0000313|EMBL:CAA88865.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-84 [Caenorhabditis elegans] clec-57 gene38306 815 1020 805 2052 2074 1983 27.32446491592 34.1044916972 28.1579355394117 59.86869236 64.284995304 58.24935825 4.13985488464021e-09 1.20281179512437 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms CUB domain;; Lectin C-type domain Protein CLEC-57 {ECO:0000313|EMBL:CAB01148.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-57 [Caenorhabditis elegans] C10C5.5 gene18899 8 7 16 38 35 36 0.458976 0.425708 0.957672 2.20163 2.01235 2.1208 0.000387299204154494 1.80757628325844 up [E] Amino acid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; K14677|0|cel:CELE_C10C5.5|C10C5.5; Protein C10C5.5; K14677 aminoacylase [EC:3.5.1.14] (A) Arginine and proline metabolism (ko00330);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Peptidase family M20/M25/M40;; Peptidase dimerisation domain Aminoacylase-1 {ECO:0000256|PIRNR:PIRNR036696} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein C10C5.5 [Caenorhabditis elegans] F10A3.4 gene39048 78 126 113 292 265 382 2.6193816 3.82184919118 3.40937939600009 8.927618147 7.9348173 11.904620384 5.7867435520594e-07 1.56041952477835 up -- -- -- -- -- -- -- CUB-like domain Protein F10A3.4 {ECO:0000313|EMBL:CAD54131.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F10A3.4 [Caenorhabditis elegans] col-35 gene1854 4404 3644 1424 187 569 379 225.794 175.839 72.7725 9.68165 28.6998 19.0502 0.00195146209181134 -3.06781798486249 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-35 {ECO:0000313|EMBL:CAB01959.3} OS=Caenorhabditis elegans PE=4 SV=3 W Extracellular structures Protein COL-35 [Caenorhabditis elegans] msp-10 gene19088 108 190 193 71 74 72 51.3394 81.0084 86.5193 36.2742 33.2508 34.4413 0.00627875175433618 -1.1845466214406 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=2 SV=1 B Chromatin structure and dynamics Protein MSP-10 [Caenorhabditis elegans] F58D2.2 gene20404 182 241 272 104 121 116 5.54422 7.32657 8.25108 3.2132 3.67556 3.54182 0.000947629379259123 -1.03365082985957 down -- -- -- -- -- -- -- -- Protein F58D2.2 {ECO:0000313|EMBL:CAB03147.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F58D2.2 [Caenorhabditis elegans] clec-43 gene4495 7 1 2 39 29 53 0.241474 0.0606727 0.0908197 1.30097 0.963347 1.72815 7.66763983015469e-08 3.58751573153059 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-43 {ECO:0000313|EMBL:CCD66376.1} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein CLEC-43 [Caenorhabditis elegans] F55A12.6 gene1168 27 27 29 7 7 5 0.819619 0.91834 0.893435 0.35864476 0.20235349 0.1342672428879 0.000144871696922186 -2.13533229345078 down -- -- -- -- -- -- -- -- Protein F55A12.6 {ECO:0000313|EMBL:CCD65441.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F55A12.6 [Caenorhabditis elegans] F17B5.1 gene3714 691 586 542 1163 1257 1581 14.38673 12.82953 11.61581 24.86404 27.23095 34.4765 2.03651560416142e-06 1.13019456576692 up -- -- Biological Process: cell redox homeostasis (GO:0045454);; -- -- [R] General function prediction only Thioredoxin-like;; Thioredoxin;; AhpC/TSA family Protein F17B5.1, isoform a {ECO:0000313|EMBL:CAB02969.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F17B5.1, isoform a [Caenorhabditis elegans] cpt-4 gene34420 687 460 701 340 299 263 18.93548 12.58357 17.554291 8.822553 8.169439 7.33406 0.000804734692077496 -1.04305091729158 down -- -- Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; -- -- [I] Lipid transport and metabolism Choline/Carnitine o-acyltransferase Protein CPT-4 {ECO:0000313|EMBL:CCD64399.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CPT-4 [Caenorhabditis elegans] cnc-8 gene44301 41 46 23 76 105 86 677.894 789.463 414.061 1928.69 1795.14 1895.45 0.00123226899130047 1.27160793985305 up -- -- -- -- -- -- -- -- Protein CNC-8 {ECO:0000313|EMBL:CAA92131.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CNC-8 [Caenorhabditis elegans] H20E11.3 gene17821 389 527 295 166 149 67 27.15461 37.00668 20.0986 11.64236 10.36795 4.886801 0.000859262553301954 -1.67463225591357 down -- -- -- -- -- -- -- CUB-like domain Protein H20E11.3, isoform b {ECO:0000313|EMBL:CCD63086.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein H20E11.3, isoform b [Caenorhabditis elegans] col-37 gene37367 33042 27272 9443 1905 4169 3522 1506.94 1203.17 424.236 87.0264 186.599 156.391 0.00743414873871433 -2.86907185023512 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-37 {ECO:0000313|EMBL:CAB01457.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-37 [Caenorhabditis elegans] mdh-2 gene11179 6643 6327 6858 18865 17822 17708 430.817 395.853 429.713 1215.54 1135.5 1128.73 2.6757486581482e-13 1.44826738586078 up [C] Energy production and conversion Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; K00026|0|cel:CELE_F20H11.3|mdh-2; Protein MDH-2; K00026 malate dehydrogenase [EC:1.1.1.37] (A) Citrate cycle (TCA cycle) (ko00020);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200) [C] Energy production and conversion lactate/malate dehydrogenase, alpha/beta C-terminal domain;; lactate/malate dehydrogenase, NAD binding domain Malate dehydrogenase {ECO:0000256|RuleBase:RU003405} OS=Caenorhabditis briggsae PE=3 SV=1 T Signal transduction mechanisms Protein MDH-2 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_547 21 29 27 0 0 0 0.949101 1.26911 1.16065 0.0409155 0.039501 0 2.56012071857403e-13 -Inf down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92;; Glycosyltransferase family 92 Protein C14C6.7 {ECO:0000313|EMBL:CCD64463.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription -- nas-3 gene36112 49 55 19 334 299 192 3.7796 4.1338 1.486902 24.99586 22.1136 14.24863 9.17971521825125e-09 2.73550880422159 up -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; K08076|0|cel:CELE_K06A4.1|nas-3; Protein NAS-3; K08076 astacin [EC:3.4.24.21] (A) -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein NAS-3 [Caenorhabditis elegans] nac-1 gene45890 649 643 479 1257 1358 1459 16.9261792743 19.78739344294 13.72285168276 43.56258 47.39128 47.8737 2.94938257231735e-08 1.19436073646286 up [P] Inorganic ion transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; K14445|0|cel:CELE_F31F6.6|nac-1; Protein NAC-1; K14445 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 (A) -- [P] Inorganic ion transport and metabolism Sodium:sulfate symporter transmembrane region;; Citrate transporter CBN-NAC-1 protein {ECO:0000313|EMBL:EGT40345.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 T Signal transduction mechanisms Protein NAC-1 [Caenorhabditis elegans] nhr-101 gene37099 556 613 528 1164 1391 1692 29.792797 32.63407216527 28.296729 63.18135 75.2762000000001 92.7101037 9.33319359661471e-07 1.31702298905902 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-101, isoform a {ECO:0000313|EMBL:CAC42310.2} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein NHR-101, isoform a [Caenorhabditis elegans] F07G11.3 gene35270 171 138 66 5 21 5 5.67061 4.24962000054709 2.408613 0.235242 0.729302 0.224795 7.23518229814281e-05 -3.6040881037071 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein F07G11.3 {ECO:0000313|EMBL:CCD64331.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein F07G11.3 [Caenorhabditis elegans] npax-3 gene19486 36 55 26 10 6 13 5.1682 7.71173 3.6625 1.48968 0.907188 1.93598 0.00372463815126718 -2.01983489500309 down -- -- Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; -- -- [K] Transcription 'Paired box' domain;; Homeodomain-like domain;; Helix-turn-helix domain Protein NPAX-3 {ECO:0000313|EMBL:CAA97441.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein NPAX-3 [Caenorhabditis elegans] F32D8.11 gene36702 1498 1451 1580 4695 5123 5664 77.0132016001313 79.321348225 83.6868231332815 203.063268510179 207.31357857031 228.330402000002 1.60138883322376e-20 1.76649733691785 up -- -- -- -- -- -- -- -- Protein F32D8.11 {ECO:0000313|EMBL:CBH29659.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F32D8.11 [Caenorhabditis elegans] alh-1 gene10722 9020 8313 9241 24941 26293 33780 346.0877340556 324.7778331313 357.1701561607 980.4490490123 1029.9400435379 1318.6660376077 1.47454907079436e-11 1.67110310121572 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00128|0|cbr:CBG23008|Cbr-alh-1; C. briggsae CBR-ALH-1 protein; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] (A) Glycolysis / Gluconeogenesis (ko00010);; Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Glycerolipid metabolism (ko00561);; Pyruvate metabolism (ko00620) [C] Energy production and conversion Aldehyde dehydrogenase family Protein ALH-1, isoform a {ECO:0000313|EMBL:CCD67408.1} OS=Caenorhabditis elegans PE=1 SV=3 W Extracellular structures Protein ALH-1, isoform a [Caenorhabditis elegans] nhr-161 gene35144 136 116 152 267 282 296 8.144569 7.393747 8.77099810568 16.8905780277 17.6378560569923 17.61011091 0.000392104176426241 1.05761595572992 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-161 {ECO:0000313|EMBL:CCD66536.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein NHR-161 [Caenorhabditis elegans] asm-3 gene13327 380 466 218 32 46 41 11.468116 13.62845 6.468444 0.938489 1.352292 1.2257676 2.55013333776215e-06 -3.16779926326748 down -- -- Molecular Function: hydrolase activity (GO:0016787);; K12350|0|cel:CELE_W03G1.7|asm-3; Protein ASM-3, isoform A; K12350 sphingomyelin phosphodiesterase [EC:3.1.4.12] (A) Sphingolipid metabolism (ko00600);; Lysosome (ko04142) [I] Lipid transport and metabolism Calcineurin-like phosphoesterase Sphingomyelin phosphodiesterase {ECO:0000256|PIRNR:PIRNR000948} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein ASM-3, isoform a [Caenorhabditis elegans] col-36 gene6836 47047 36300 19440 1828 6094 2882 2553.0012 1884.9484 1006.3157 100.157661 314.70352 150.72908 4.88990339648056e-05 -3.25704790405385 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Putative uncharacterized protein {ECO:0000313|EMBL:EGT55763.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein COL-36 [Caenorhabditis elegans] C35C5.8 gene44702 286 290 277 761 915 1468 14.2105140000009 13.065600000014 12.659225031 34.7594300105073 42.07613 64.49315 0.00173792764766332 1.87636922479048 up -- -- -- -- -- -- -- -- Protein C35C5.8, isoform a {ECO:0000313|EMBL:CAC42263.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C35C5.8, isoform a [Caenorhabditis elegans] C50F4.8 gene36128 780 878 854 1654 2129 2771 42.2545228 49.24205 45.768175 92.398404 120.702581 158.335641 0.000355565335109181 1.37776024317251 up -- -- -- -- -- -- -- -- Protein C50F4.8 {ECO:0000313|EMBL:CAA94743.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C50F4.8 [Caenorhabditis elegans] K08C7.4 gene19437 88 74 71 472 531 738 3.99485 3.41908 3.820543 25.79567 24.3366595 37.74531 1.61732234536405e-11 2.89495457006106 up -- -- -- -- -- -- -- -- Protein K08C7.4 {ECO:0000313|EMBL:CAA94294.2} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein K08C7.4 [Caenorhabditis elegans] clec-76 gene14174 516 648 243 14 8 7 28.5615 33.44625 12.05592 0.531849 0.4576417776 0.38131752354 2.86272039794147e-08 -5.61139496014771 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-76 {ECO:0000313|EMBL:CCD71387.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-76 [Caenorhabditis elegans] col-89 gene10583 1275 1211 563 212 353 254 75.22972 66.1781378324 31.091969928 12.110822 19.4282384425 14.2950807114 0.0048502857876268 -1.9042109852326 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-89 {ECO:0000313|EMBL:CAA84800.1} OS=Caenorhabditis elegans PE=4 SV=1 F Nucleotide transport and metabolism Protein COL-89 [Caenorhabditis elegans] T19D12.4 gene6625 7913 9776 6878 4495 3716 4124 144.588910867 178.638883618 122.155929918 81.294437153 67.368459094 75.119194626 3.5640684845195e-05 -1.00207704162231 down -- -- -- -- -- -- -- von Willebrand factor type A domain Protein T19D12.4, isoform a {ECO:0000313|EMBL:CCD71842.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein T19D12.4, isoform a [Caenorhabditis elegans] srh-237 gene39449 11 6 8 40 48 47 5.4838729 2.8686026 0.62079285471 5.907319 6.740318 4.72139 6.04835888823932e-07 2.42539911451685 up -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri;; Serpentine type 7TM GPCR chemoreceptor Str Protein SRH-237, isoform a {ECO:0000313|EMBL:CCM09376.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms hypothetical protein T05E12.7 - Caenorhabditis elegans B0379.7 gene2716 225 259 323 136 86 153 8.6083519412 9.6572039132 12.0030239953 5.19276944496 3.2379084403 5.76838973213 0.000288858584870044 -1.11254894357585 down -- -- -- -- -- -- -- -- Protein B0379.7 {ECO:0000313|EMBL:CAB54186.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein B0379.7 [Caenorhabditis elegans] col-95 gene12757 2199 1672 2745 7419 6662 4645 112.251 78.3883 130.045 356.458 315.187 219.135 1.88235910595765e-05 1.49262286187455 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Nematode cuticle collagen N-terminal domain;; Collagen triple helix repeat (20 copies) Protein COL-95 {ECO:0000313|EMBL:CAD66222.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein COL-95 [Caenorhabditis elegans] C05C8.8 gene35255 271 220 110 30 48 27 12.982521025 9.5545905 5.2298674 1.1889672012 1.654749 0.937791436 0.00106120463868382 -2.52561243283531 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C05C8.8 {ECO:0000313|EMBL:CCD63097.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C05C8.8 [Caenorhabditis elegans] cpr-1 gene37291 5493 5132 5703 11359 13572 17375 347.311 315.92 348.162 715.388 835.6 1070.26 1.36873354828576e-05 1.36736107962412 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_C52E4.1|cpr-1; Protein CPR-1; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein CBR-CPR-1 {ECO:0000313|EMBL:CAP39674.1} OS=Caenorhabditis briggsae PE=3 SV=1 G Carbohydrate transport and metabolism Protein CPR-1 [Caenorhabditis elegans] pmp-5 gene35017 257 265 236 1022 1185 1492 7.9484897 8.37923 7.189197 32.45218 37.845863 46.649617 4.53255865389503e-13 2.28036727996999 up [R] General function prediction only Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; -- -- [IR] Lipid transport and metabolism;; General function prediction only ABC transporter transmembrane region 2;; ABC transporter;; NACHT domain Protein PMP-5, isoform a {ECO:0000313|EMBL:CCD71212.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein PMP-5, isoform a [Caenorhabditis elegans] F36G3.2 gene44129 162 163 190 440 380 404 8.82291976859915 9.0682244606571 11.009562403 25.49654754 21.079316802 22.643548246 4.03496482263748e-06 1.24136949763422 up [KR] Transcription;; General function prediction only -- -- -- -- -- Acetyltransferase (GNAT) domain Protein CBG01897 {ECO:0000313|EMBL:CAP23096.2} OS=Caenorhabditis briggsae PE=4 SV=2 R General function prediction only Protein F36G3.2 [Caenorhabditis elegans] kat-1 gene6806 5184 5035 5368 13603 13854 15078 179.24 176.0218 199.2192 487.1597 524.7189 563.3977 1.8988381806715e-13 1.44116240835978 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; K00626|0|cel:CELE_T02G5.8|kat-1; Protein KAT-1; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] (A) Fatty acid degradation (ko00071);; Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Terpenoid backbone biosynthesis (ko00900);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Thiolase, N-terminal domain;; Thiolase, C-terminal domain;; Beta-ketoacyl synthase, N-terminal domain Protein KAT-1 {ECO:0000313|EMBL:CCD69179.1} OS=Caenorhabditis elegans PE=3 SV=2 C Energy production and conversion Protein KAT-1 [Caenorhabditis elegans] pho-1 gene6014 1089 1123 892 2481 2085 1955 54.9136 56.0712 44.3026 124.881 103.711 98.3124 2.31349899585106e-07 1.06233403545253 up -- -- Molecular Function: acid phosphatase activity (GO:0003993);; -- -- [I] Lipid transport and metabolism Histidine phosphatase superfamily (branch 2) Protein PHO-1 {ECO:0000313|EMBL:CCD66681.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein PHO-1 [Caenorhabditis elegans] ZK488.5 gene33051 49 38 48 10 4 0 1.92088 1.44645 1.83432 0.40536 0.176343 0.0376002 2.96185454677458e-10 -3.28391732088226 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein ZK488.5 {ECO:0000313|EMBL:CCD71524.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK488.5 [Caenorhabditis elegans] F17A9.4 gene34803 1422 1251 1371 3350 3193 3569 48.00708 42.28445 46.97868 129.9168 121.10311 136.56336 1.61321177532207e-11 1.31477736745099 up [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein F17A9.4 {ECO:0000313|EMBL:CCD69357.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein F17A9.4 [Caenorhabditis elegans] clec-4 gene8726 1246 1999 2013 229 180 167 51.6868 77.8487 78.8581 9.5294 7.00392 6.61735 4.76264457088275e-13 -3.19820304310733 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-4 {ECO:0000313|EMBL:CAB54396.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-4 [Caenorhabditis elegans] spp-14 gene43402 2066 2733 1298 3407 4524 4542 3532.9 4227.28 2124.88 7134.6 7358.2 8381.92 0.0017625917445813 1.0254875334329 up -- -- -- -- -- -- -- -- Protein SPP-14 {ECO:0000313|EMBL:CCD67566.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SPP-14 [Caenorhabditis elegans] fbxa-128 gene12635 239 251 262 120 104 105 17.7713725588 20.7694833697 21.3378146413 10.6456863604 8.9039639562 9.0649142092 7.16814923036714e-05 -1.20048254890015 down -- -- -- -- -- -- -- FTH domain Protein FBXA-128 {ECO:0000313|EMBL:CAB55092.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein FBXA-128 [Caenorhabditis elegans] K09D9.9 gene34115 106 87 35 4 6 3 9.95252 8.2019 3.31474 0.442681 0.60477 0.363827 0.000149040945089855 -4.14174349941945 down -- -- -- -- -- -- -- -- Protein K09D9.9 {ECO:0000313|EMBL:CCD61375.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K09D9.9 [Caenorhabditis elegans] C25A11.1 gene43950 37 37 50 85 104 107 3.740163676107 2.7455440149 4.44653716 9.7181903253374 6.4167483 6.92641159 0.00112045402894144 1.24906244189109 up -- -- -- -- -- -- -- -- Protein C25A11.1 {ECO:0000313|EMBL:CCD62267.1} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein C25A11.1 [Caenorhabditis elegans] Y53C10A.10 gene3346 104 111 138 50 55 62 0.8278054 0.8766823 1.0782184 0.379251 0.427621 0.4802844 0.00332763032694509 -1.0861675317255 down -- -- -- -- -- -- -- -- Protein Y53C10A.10 {ECO:0000313|EMBL:CAA22144.3} OS=Caenorhabditis elegans PE=4 SV=3 Q Secondary metabolites biosynthesis, transport and catabolism Protein Y53C10A.10 [Caenorhabditis elegans] ZK185.4 gene14376 246 180 106 13 39 12 25.1571453043 17.8510798786 11.241235417 1.5041559805 3.9457922075 2.147775 0.000103375680353633 -3.06316209296236 down -- -- -- -- -- [T] Signal transduction mechanisms Frag1/DRAM/Sfk1 family Protein ZK185.4, isoform a {ECO:0000313|EMBL:CCD70162.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK185.4 [Caenorhabditis elegans] pyk-2 gene19526 1095 1106 1039 2445 2535 2682 42.251621539 42.888939065 40.928569545 98.72563572 100.671442543 107.436532911 6.64192826001856e-10 1.23442222547367 up [G] Carbohydrate transport and metabolism Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: pyruvate kinase activity (GO:0004743);; Biological Process: glycolytic process (GO:0006096);; Molecular Function: potassium ion binding (GO:0030955);; K00873|0|cbr:CBG05956|Hypothetical protein CBG05956; K00873 pyruvate kinase [EC:2.7.1.40] (A) Glycolysis / Gluconeogenesis (ko00010);; Purine metabolism (ko00230);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [G] Carbohydrate transport and metabolism Pyruvate kinase, barrel domain;; Pyruvate kinase, alpha/beta domain;; HpcH/HpaI aldolase/citrate lyase family Pyruvate kinase {ECO:0000256|RuleBase:RU000504} OS=Caenorhabditis elegans PE=3 SV=2 G Carbohydrate transport and metabolism Protein PYK-2, isoform a [Caenorhabditis elegans] pals-31 gene33070 94 88 73 164 193 208 5.6789985953 5.890585518441 5.396123454 10.2650372847 12.922439 13.218270864033 0.000478371584509693 1.14059772076368 up -- -- -- -- -- -- -- -- Protein F48G7.2, isoform b {ECO:0000313|EMBL:CCD70360.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F48G7.2, isoform b [Caenorhabditis elegans] T24C4.8 gene9577 31 39 34 10 11 20 3.377875 4.5602108 3.513379 1.072793533 1.11671 2.121499 0.00980680787298092 -1.34820513527842 down -- -- -- -- -- -- -- Tight junction protein, Claudin-like Protein T24C4.8 {ECO:0000313|EMBL:CCD69962.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T24C4.8 [Caenorhabditis elegans] K02E11.7 gene38200 46 35 20 4 7 9 22.4084 15.2718 9.29758 2.4573 3.35024 4.71237 0.00178452418889321 -2.34269438547766 down -- -- -- -- -- -- -- -- Protein K02E11.7 {ECO:0000313|EMBL:CAB01224.2} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein K02E11.7 [Caenorhabditis elegans] R06C7.2 gene1802 982 1090 1066 270 274 191 37.1234226392 44.2918600242569 37.736573536164 8.66668602707 9.0578426287 6.1692730515806 5.40899572033532e-21 -2.10223406505577 down -- -- -- -- -- [DR] Cell cycle control, cell division, chromosome partitioning;; General function prediction only -- Protein R06C7.2 {ECO:0000313|EMBL:CAA95841.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein R06C7.2 [Caenorhabditis elegans] grd-2 gene40641 214 223 184 75 97 81 4.2248 4.35586 3.62914 1.48752 1.91813 1.59373 3.39609945623331e-05 -1.30277145885197 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; -- -- -- -- Ground-like domain;; Hint module Protein GRD-2 {ECO:0000313|EMBL:CAB04405.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein GRD-2 [Caenorhabditis elegans] M70.1 gene13710 112 119 137 55 56 72 2.371536 2.60909156761 2.9715037639 1.208496 1.2579440728 1.599827 0.00612906034672129 -1.01425137263438 down -- -- -- -- -- -- -- Domain of unknown function Protein M70.1, isoform b {ECO:0000313|EMBL:CDH93481.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown M70.1, isoform b [Caenorhabditis elegans] C04E12.5 gene33904 606 595 369 1038 1168 1305 25.615798 21.048109 10.032386 26.7526375 30.072332 34.14957495 1.748261240029e-07 1.15356202683318 up -- -- -- -- -- -- -- Domain of unknown function (DUF750) Protein C04E12.5 {ECO:0000313|EMBL:CCD62923.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C04E12.5 [Caenorhabditis elegans] F55G11.8 gene20329 1991 2096 1470 509 382 400 151.791 159.874 111.567 39.6966 29.2476 30.9121 1.31948562766968e-13 -2.11473279504932 down -- -- -- -- -- -- -- CUB-like domain Protein F55G11.8 {ECO:0000313|EMBL:CAB05220.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F55G11.8 [Caenorhabditis elegans] ilys-2 gene13760 3 0 0 87 145 228 1.2708 0 0 39.0624 56.4395 95.8002 1.13227300872416e-08 7.2506090206841 up -- -- Molecular Function: lysozyme activity (GO:0003796);; -- -- -- -- Destabilase Protein ILYS-2 {ECO:0000313|EMBL:CCD65530.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ILYS-2 [Caenorhabditis elegans] col-185 gene45400 6042 5705 2067 423 907 729 324.7222 284.25411 105.67079 22.3610026846 45.67573 37.6150088582 0.00324087278228521 -2.75325093238663 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-185 {ECO:0000313|EMBL:CAE11316.1} OS=Caenorhabditis elegans PE=4 SV=1 D Cell cycle control, cell division, chromosome partitioning Protein COL-185 [Caenorhabditis elegans] folt-2 gene33710 289 332 238 2439 2327 2015 15.7814945596428 17.7418340407703 12.533384746823 130.004305245258 120.777991156587 105.12233034449 4.7821554177508e-46 2.97242918189958 up -- -- Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; -- -- [H] Coenzyme transport and metabolism Reduced folate carrier Putative uncharacterized protein {ECO:0000313|EMBL:EGT30842.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein FOLT-2 [Caenorhabditis elegans] F02C12.1 gene45354 493 425 425 812 856 1145 10.34909 9.03939 8.97848 17.42079 18.16417 24.39306 0.000100911330827818 1.05988004563042 up -- -- -- -- -- -- -- Zinc finger, ZZ type Protein F02C12.1 {ECO:0000313|EMBL:CAA91022.4} OS=Caenorhabditis elegans PE=4 SV=5 R General function prediction only Protein F02C12.1 [Caenorhabditis elegans] Y71G12B.18 gene284 358 271 328 53 32 4 27.9045103303 20.31590762136 24.50610477716 4.18908329858 2.4384425327 0.4517376366 6.31811337658182e-29 -3.43937850188039 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein Y71G12B.18, isoform a {ECO:0000313|EMBL:CCD67988.1} OS=Caenorhabditis elegans PE=4 SV=3 V Defense mechanisms Protein Y71G12B.18 [Caenorhabditis elegans] Y53G8AM.5 gene10145 6839 6456 4197 184 142 142 916.62 825.749 541.866 24.8007 18.3563 18.7884 1.12959729068308e-24 -5.23327480089654 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein Y53G8AM.5 {ECO:0000313|EMBL:CCD73804.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y53G8AM.5 [Caenorhabditis elegans] F54B8.4 gene38876 1197 1889 1409 212 268 227 914.038800000003 1330.8031 1090.4345 181.004 196.5626 170.5379 1.61321177532207e-11 -2.67538991829604 down -- -- -- -- -- -- -- Death-associated protein Protein F54B8.4, isoform b {ECO:0000313|EMBL:CCG28143.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F54B8.4, isoform b [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_326 61 85 83 44 22 34 1.2656271754168 2.056354509 1.8195710207 0.993348 0.5073424556 0.773981 0.00358994701320143 -1.20374002986636 down -- -- -- -- -- -- -- -- Protein Y54G2A.13 {ECO:0000313|EMBL:CCD83501.2} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only -- best-7 gene19657 81 112 83 191 224 230 3.139247 4.13665 3.13422 7.3768 8.64495 8.53897 0.000105609119984449 1.21781007146066 up -- -- -- -- -- [R] General function prediction only Bestrophin, RFP-TM, chloride channel Protein BEST-7 {ECO:0000313|EMBL:CAA92730.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein BEST-7 [Caenorhabditis elegans] idh-1 gene18916 5127 5691 6315 15264 14056 14574 196.32604 213.6638 242.29928 594.62602 538.4369 557.13985 6.99881732414603e-12 1.3499049670654 up [C] Energy production and conversion Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; K00031|0|cbr:CBG21657|Hypothetical protein CBG21657; K00031 isocitrate dehydrogenase [EC:1.1.1.42] (A) Citrate cycle (TCA cycle) (ko00020);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230);; Peroxisome (ko04146) [C] Energy production and conversion Isocitrate/isopropylmalate dehydrogenase Isocitrate dehydrogenase [NADP] {ECO:0000256|PIRNR:PIRNR000108} OS=Caenorhabditis elegans PE=3 SV=1 C Energy production and conversion Protein IDH-1, isoform b [Caenorhabditis elegans] C14C6.5 gene33029 4779 7328 4978 1958 1835 1517 1149.0000371624 1611.0400563867 1116.0400534338 482.5150629763 412.6030523709 359.2730694329 7.72741719975687e-06 -1.69409266712108 down -- -- -- -- -- -- -- ShK domain-like;; CC domain Protein C14C6.5 {ECO:0000313|EMBL:CCD64469.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C14C6.5 [Caenorhabditis elegans] cat-4 gene36557 4442 4319 2569 1421 1301 937 335.90206 328.777 197.35100724331 112.76213 100.058130501 72.0404 0.000203933630685055 -1.6401168370423 down [H] Coenzyme transport and metabolism -- K01495|3.35098e-165|cel:CELE_F32G8.6|cat-4; Protein CAT-4; K01495 GTP cyclohydrolase I [EC:3.5.4.16] (A) Folate biosynthesis (ko00790) [H] Coenzyme transport and metabolism GTP cyclohydrolase I;; QueF-like protein CBN-CAT-4 protein {ECO:0000313|EMBL:EGT48556.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein CAT-4 [Caenorhabditis elegans] dgat-2 gene39686 300 264 167 479 430 647 20.5561 17.4543 11.2959 33.3804 28.8817 43.8681 0.00351195888352897 1.08225062236954 up -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [I] Lipid transport and metabolism Diacylglycerol acyltransferase Protein DGAT-2 {ECO:0000313|EMBL:CAB04533.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein DGAT-2 [Caenorhabditis elegans] K11H12.4 gene13374 325 390 443 32 13 13 17.6295 20.5309 23.3198 1.70827 0.739863 0.723119 1.12900032809014e-42 -4.32992992018377 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein K11H12.4 {ECO:0000313|EMBL:CCD70973.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein K11H12.4 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_251 13 13 13 34 52 65 0.60146253153 0.61789266174 0.5634718721 1.602168 2.58182 3.26536 0.000261974464762025 1.94747390536879 up -- -- -- K00036|2.97942e-11|cel:CELE_B0035.5|gspd-1; Protein GSPD-1; K00036 glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49] (A) Pentose phosphate pathway (ko00030);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200) -- -- -- Glucose-6-phosphate 1-dehydrogenase {ECO:0000256|RuleBase:RU000497} OS=Caenorhabditis briggsae PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones -- ttr-22 gene37405 20 27 20 75 89 106 7.69197 9.35079 7.18663 29.6879 31.0629 39.9748 2.477550902243e-07 2.00430548148303 up -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-22 {ECO:0000313|EMBL:CAB01580.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TTR-22 [Caenorhabditis elegans] T05G5.5 gene12215 3217 3235 3398 6007 6635 7661 169.39888 166.04826 176.5981 344.60155 371.17759 438.4658 1.66454335477804e-07 1.03683071289676 up [H] Coenzyme transport and metabolism Molecular Function: dephospho-CoA kinase activity (GO:0004140);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; K00859|9.74084e-154|cbr:CBG10005|Hypothetical protein CBG10005; K00859 dephospho-CoA kinase [EC:2.7.1.24] (A) Pantothenate and CoA biosynthesis (ko00770) [H] Coenzyme transport and metabolism Dephospho-CoA kinase Dephospho-CoA kinase 2 OS=Caenorhabditis elegans PE=3 SV=1 D Cell cycle control, cell division, chromosome partitioning Protein T05G5.5, isoform d [Caenorhabditis elegans] gln-3 gene29888 4184 3155 3696 9762 11220 14239 178.4562531374 125.3806020955 153.566480048814 425.799870026422 453.5743002311 579.56034362367 2.03093325256752e-08 1.66774506072991 up [E] Amino acid transport and metabolism Molecular Function: glutamate-ammonia ligase activity (GO:0004356);; Biological Process: glutamine biosynthetic process (GO:0006542);; Biological Process: nitrogen compound metabolic process (GO:0006807);; K01915|0|cbr:CBG13820|Cbr-gln-3; C. briggsae CBR-GLN-3 protein; K01915 glutamine synthetase [EC:6.3.1.2] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Glyoxylate and dicarboxylate metabolism (ko00630);; Nitrogen metabolism (ko00910);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Glutamine synthetase, catalytic domain;; Glutamine synthetase, beta-Grasp domain Glutamine synthetase {ECO:0000256|RuleBase:RU004356} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein GLN-3, isoform a [Caenorhabditis elegans] ugt-13 gene34378 1682 1982 1617 465 470 418 64.2677 75.574 61.3051 17.8726 17.8734 15.9623 1.37402473109464e-21 -1.97247011420471 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-13 {ECO:0000313|EMBL:CCD62606.1} OS=Caenorhabditis elegans PE=4 SV=2 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein UGT-13 [Caenorhabditis elegans] clec-31 gene39343 5 12 15 41 57 79 0.344383 0.814212 0.987246 2.784694 3.810916 5.291835 7.16814923036714e-05 2.46369572978297 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-31 {ECO:0000313|EMBL:CAB04414.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-31 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_31 0 0 0 22 29 31 0 0.0432618 0 1.255829 1.3832266977 1.450902034 8.0219300697499e-14 Inf up -- -- -- -- -- -- -- Domain of unknown function (DUF316) Protein F15H9.1 {ECO:0000313|EMBL:CAB04116.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown -- elo-6 gene15453 2202 2364 1858 9735 10916 12068 225.81120980923 236.930259744627 183.678422754 1016.09024072275 1106.40016876005 1250.93172000919 5.86122477898107e-34 2.34148853935934 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein ELO-6 [Caenorhabditis elegans] daf-28 gene40413 198 194 96 494 508 487 22.09344054 20.1188996854 12.49261 55.2128362333 54.4477449686 53.10900371215 3.5561689413882e-10 1.60081744891521 up -- -- -- -- -- -- -- Nematode insulin-related peptide beta type Protein DAF-28 {ECO:0000313|EMBL:CAB61047.2} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein DAF-28 [Caenorhabditis elegans] Y53G8AM.4 gene10144 67 76 70 11 10 3 6.90015 7.60991 6.83408 1.14653 1.02169 0.393798 1.56763663111878e-12 -3.15995812120095 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Zinc finger, C3HC4 type (RING finger) Protein Y53G8AM.4 {ECO:0000313|EMBL:CCD73803.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y53G8AM.4 [Caenorhabditis elegans] F43C9.1 gene42234 95 101 74 208 203 263 4.990089 4.459628 3.019885 8.80968 8.44586 10.36452 2.10386238945153e-05 1.31253427258925 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- F-box domain Protein F43C9.1 {ECO:0000313|EMBL:CCD67082.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F43C9.1 [Caenorhabditis elegans] T28A11.19 gene33865 470 431 165 15 23 72 75.1962 65.7929 25.8165 2.44902 3.62634 11.6098 0.000658228447519972 -3.28123902365607 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T28A11.19 {ECO:0000313|EMBL:CCD70575.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T28A11.19 [Caenorhabditis elegans] C03G6.5 gene35299 515 492 353 174 201 262 71.451 65.1354 47.2628 24.3682 26.6506 35.9273 0.000277201435600146 -1.10112382466217 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein C36C5.14 {ECO:0000313|EMBL:CCD66865.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C03G6.5 [Caenorhabditis elegans] Y46D2A.2 gene5374 293 360 315 148 129 79 15.535459 18.177754 15.913264 7.732261 6.51905993103 4.13867500001351 2.44174396570453e-07 -1.45220302042971 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein Y46D2A.2 {ECO:0000313|EMBL:CCD69508.2} OS=Caenorhabditis elegans PE=4 SV=5 R General function prediction only Protein Y46D2A.2 [Caenorhabditis elegans] T01G5.1 gene38551 209 220 182 90 93 83 8.4315700975 8.90523806457077 7.25680398533 3.65658212832423 3.69972300009935 3.3950520285 0.000145531593243995 -1.20764652591286 down -- -- Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain Protein T01G5.1 {ECO:0000313|EMBL:CAB03265.2} OS=Caenorhabditis elegans PE=4 SV=2 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein T01G5.1 [Caenorhabditis elegans] K04G2.7 gene2036 79 72 38 137 149 122 6.4783373624 6.12084727220003 3.6580802 11.9759779863001 12.5903108 10.4982664462 0.00196412157993607 1.10136199180612 up -- -- -- -- -- -- -- Tc5 transposase DNA-binding domain Protein K04G2.7, isoform a {ECO:0000313|EMBL:CAB00044.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein K04G2.7, isoform a [Caenorhabditis elegans] T10C6.15 gene38999 236 214 161 44 54 84 18.23902 16.71851 12.61664 3.717791 4.725642 6.8893 9.13873549040182e-08 -1.75344912462243 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain Protein T10C6.15, isoform a {ECO:0000313|EMBL:CBO25482.1} OS=Caenorhabditis elegans PE=4 SV=1 B Chromatin structure and dynamics Protein T10C6.15, isoform a [Caenorhabditis elegans] aqp-3 gene19548 47 50 45 10 12 5 2.813942 2.982561152 2.59262294447 0.5877050155322 0.7341128687 0.35429701179936 4.70038965199738e-07 -2.40371248969454 down [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|0|cel:CELE_Y69E1A.7|aqp-3; Protein AQP-3; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-3, isoform a {ECO:0000313|EMBL:CAA22259.1} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein AQP-3 [Caenorhabditis elegans] Y49G5A.1 gene34503 742 678 225 106 46 35 121.573 104.233 35.7428 17.599 7.2839 5.76696 0.00304737906792401 -3.14999840661395 down -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain Protein Y49G5A.1 {ECO:0000313|EMBL:CCD61496.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y49G5A.1 [Caenorhabditis elegans] cyp-13A12 gene13024 46 18 33 310 258 227 1.900778 0.71426703922 1.28528987608 12.81973 10.23717 9.02075 3.26997036847652e-22 3.02566201133864 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_F14F7.3|cyp-13A12; Protein CYP-13A12; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-13A12 {ECO:0000313|EMBL:CAB04113.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A12 [Caenorhabditis elegans] C10G11.6 gene1492 1852 1854 2093 3677 4305 4827 77.3094978668681 78.2457277337722 85.87163034074 150.3106321 169.122334185378 190.183169800001 6.23093212984656e-09 1.13684850397876 up -- -- -- -- -- -- -- -- Protein C10G11.6, isoform b {ECO:0000313|EMBL:CCD64189.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C10G11.6, isoform b [Caenorhabditis elegans] clec-198 gene32823 214 257 119 59 71 70 5.96989 6.72833 3.08223 1.50244 1.82587 1.81167 0.0076688992665172 -1.56841658288054 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-198 {ECO:0000313|EMBL:CAB05164.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein CLEC-198 [Caenorhabditis elegans] math-15 gene4835 56 54 61 344 342 328 3.6878955304 3.656222182333 4.16804260041 22.1154809021 22.79018285728 22.46519381085 3.95581898889939e-19 2.56050668835664 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- MATH domain Protein MATH-15 {ECO:0000313|EMBL:CCD64669.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein MATH-15 [Caenorhabditis elegans] T13F3.6 gene39111 32 30 21 89 149 199 8.0439 6.90098 4.95613 22.0802 34.4091 48.1826 0.000583272512986649 2.39066529670642 up -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T13F3.6 {ECO:0000313|EMBL:CAB07673.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T13F3.6 [Caenorhabditis elegans] gly-1 gene8131 51 74 70 29 35 14 2.121437 2.814176363 2.6659354374 0.888471 0.7933706 0.7915473976 0.00192474148905042 -1.33024937773136 down -- -- Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; -- -- [G] Carbohydrate transport and metabolism Core-2/I-Branching enzyme Protein GLY-1 {ECO:0000313|EMBL:CAA85457.1} OS=Caenorhabditis elegans PE=2 SV=1 R General function prediction only Protein GLY-1 [Caenorhabditis elegans] F32D8.8 gene36711 76 74 24 5 10 1 4.92423155674 4.821332 1.57311282445 0.37227258107 0.670440792879 0.128217259512 0.00201213391713479 -3.45312307935659 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF268 Protein F32D8.8 {ECO:0000313|EMBL:CAA98451.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F32D8.8 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_557 45 64 28 115 136 122 2.6385678751 3.692716762 1.599322634 6.793243805 7.9260965179 7.1391253545 5.51569498583674e-05 1.43719457374541 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- BTB/POZ domain Protein BTB-21 {ECO:0000313|EMBL:CCD64884.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription PREDICTED: speckle-type POZ protein A-like [Fopius arisanus] ugt-19 gene16953 1693 2635 2141 1177 745 443 66.4737 102.8432 82.8076 46.75487 29.07982 17.21702771 0.000354720112257854 -1.46181534980605 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-19 {ECO:0000313|EMBL:CCD72378.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein UGT-19 [Caenorhabditis elegans] nas-28 gene11045 587 552 240 64 112 88 23.0929 21.445 9.28711 2.5332 4.35018 3.41468 0.00178106783170063 -2.39257148359621 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; K08076|0|cel:CELE_F42A10.8|nas-28; Protein NAS-28; K08076 astacin [EC:3.4.24.21] (A) -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein NAS-28 [Caenorhabditis elegans] R03D7.5 gene8145 9498 9444 8054 3374 2656 2109 1198.634 1244.2813 1087.5534 457.36466 380.96506 297.03876 1.02333126566074e-19 -1.73907903617083 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; K03083|0|cel:CELE_R03D7.5|R03D7.5; Protein R03D7.5; K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26] (A) ErbB signaling pathway (ko04012);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340) [G] Carbohydrate transport and metabolism Protein kinase domain;; Protein tyrosine kinase;; Kinase-like Putative uncharacterized protein {ECO:0000313|EMBL:EGT40906.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 A RNA processing and modification Protein R03D7.5 [Caenorhabditis elegans] col-7 gene1861 282 398 363 209 138 149 10.06306 14.43437 13.30003 7.44143 4.60372838 5.175294 0.000133957898161451 -1.08077261305576 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-62 {ECO:0000313|EMBL:CAB01958.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-7 [Caenorhabditis elegans] C50F7.3 gene18308 24 35 42 14 14 7 2.11687 2.98011 3.57062 1.23466 1.26319 0.669114 0.00324255630332185 -1.5371103314522 down -- -- -- -- -- [S] Function unknown -- Protein C50F7.3 {ECO:0000313|EMBL:CCD67451.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C50F7.3 [Caenorhabditis elegans] T23F6.5 gene20256 415 390 226 58 96 55 12.0594 11.0975 6.53852 1.71392 2.74957 1.57826 9.80348556032095e-06 -2.31052567716649 down -- -- -- -- -- -- -- -- Protein T23F6.5 {ECO:0000313|EMBL:CAB05628.3} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein T23F6.5 [Caenorhabditis elegans] F11C7.2 gene46657 311 343 147 30 35 45 92.974 94.4052 43.3263 9.89863 10.0897 13.702 0.000119921145467765 -2.8716139038322 down -- -- -- -- -- -- -- Thrombospondin type 1 domain Protein F11C7.2 {ECO:0000313|EMBL:CCD66910.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F11C7.2 [Caenorhabditis elegans] spe-27 gene16438 497 400 278 99 176 118 77.0707000097484 55.5328 43.23402322391 13.7831376259 22.4198300003031 13.25945627132 0.000668114877987673 -1.58759858169149 down -- -- -- -- -- -- -- -- CRE-SPE-27 protein {ECO:0000313|EMBL:EFO87373.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 H Coenzyme transport and metabolism Protein SPE-27 [Caenorhabditis elegans] C13A2.4 gene35263 535 467 188 13 66 45 41.19248 36.04351 14.28133 1.074409 5.032843 3.58185 0.000550039973913516 -3.26831295763446 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C13A2.4 {ECO:0000313|EMBL:CCD63105.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C13A2.4 [Caenorhabditis elegans] ugt-36 gene35227 47 72 30 200 213 225 2.056439 3.1570416256 1.3145597848 8.616911 9.23515 9.7289402519 2.14197467263192e-11 2.09056066036242 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-36 {ECO:0000313|EMBL:CCD64426.1} OS=Caenorhabditis elegans PE=4 SV=2 P Inorganic ion transport and metabolism Protein UGT-36 [Caenorhabditis elegans] F59A7.2 gene33432 245 272 260 648 957 944 124.4159 125.8051 130.9076 372.9039 419.8553 488.2157 3.93432541982229e-08 1.70780990902078 up -- -- -- -- -- -- -- -- Protein F59A7.2 {ECO:0000313|EMBL:CCD72096.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F59A7.2 [Caenorhabditis elegans] alh-5 gene33425 907 1021 1082 2067 2304 2647 42.34953 46.8155 47.05406 95.0141 104.0389 118.3851 1.78190674881675e-09 1.21485443558496 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00129|0|cel:CELE_T08B1.3|alh-5; Protein ALH-5; K00129 aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] (A) Glycolysis / Gluconeogenesis (ko00010);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [C] Energy production and conversion Aldehyde dehydrogenase family;; Acyl-CoA reductase (LuxC) Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492} OS=Caenorhabditis elegans PE=3 SV=1 Z Cytoskeleton Protein ALH-5 [Caenorhabditis elegans] sqst-1 gene19992 15448 11754 16450 6144 6112 9636 397.9530988697 304.600112427 419.155116048 159.060835709 158.3512994319 248.728310623 0.0007505486197995 -1.00176143885157 down -- -- Molecular Function: zinc ion binding (GO:0008270);; -- -- [R] General function prediction only Zinc finger, ZZ type Protein SQST-1, isoform a {ECO:0000313|EMBL:CAA92982.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T12G3.1, isoform a [Caenorhabditis elegans] F18E3.11 gene35321 127 153 161 220 364 307 349.033 368.221 409.492 736.877 925.029 936.066 0.00504957603385347 1.00877012028305 up -- -- -- -- -- -- -- -- Protein F18E3.11 {ECO:0000313|EMBL:CCD69665.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F18E3.11 [Caenorhabditis elegans] fat-3 gene19075 2633 2608 2634 5269 6443 9568 126.18424544 126.62179783 125.74323716 249.60080721 307.51663326 459.52605232 0.00358994701320143 1.4284186209079 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Fatty acid desaturase;; Cytochrome b5-like Heme/Steroid binding domain CBN-FAT-3 protein {ECO:0000313|EMBL:EGT37896.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein FAT-3, isoform a [Caenorhabditis elegans] glb-19 gene19429 82 127 61 169 176 215 5.71741003429537 8.75991933192719 4.24457590000003 11.2168284865 11.8979292471605 14.356262311233 0.0015718566862102 1.04529176988692 up -- -- Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; -- -- [C] Energy production and conversion Globin Protein GLB-19, isoform a {ECO:0000313|EMBL:CAX65059.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein GLB-19, isoform a [Caenorhabditis elegans] C08E8.10 gene39916 229 242 194 77 76 150 68.6455 54.880891 48.10928 28.8143 15.8702616663 32.615038349 0.000265856878593308 -1.13987517081304 down -- -- -- -- -- -- -- -- Protein C08E8.10 {ECO:0000313|EMBL:CAQ35016.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C08E8.10 [Caenorhabditis elegans] T08H10.1 gene34272 2727 2779 2229 5273 5593 5804 174.83724781 174.9009024379 142.59505896 342.21948965 350.382046372 368.51197 1.86494014734825e-08 1.10026457186443 up [R] General function prediction only -- -- -- [R] General function prediction only Aldo/keto reductase family Protein T08H10.1 {ECO:0000313|EMBL:CCD72269.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T08H10.1 [Caenorhabditis elegans] gst-15 gene8948 745 608 402 170 148 251 69.601905 53.03313 38.87304 16.4863013 14.355363950639 23.703633 0.000856287309677504 -1.6324349219251 down [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-15 {ECO:0000313|EMBL:CAB02290.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-15 [Caenorhabditis elegans] Y17D7C.2 gene40047 35 34 27 65 83 102 2.403514 2.482382378432 1.809330149307 4.929881186965 6.131640398108 7.209480565656 0.000571243534765148 1.37428116410568 up -- -- -- -- -- -- -- -- Protein Y17D7C.2 {ECO:0000313|EMBL:CAA16296.4} OS=Caenorhabditis elegans PE=4 SV=4 K Transcription Protein Y17D7C.2 [Caenorhabditis elegans] ZK742.3 gene35484 563 713 525 296 258 154 28.2773 36.1653 26.6231 15.45 13.0976 7.92994 2.02442770090272e-06 -1.35632588227598 down [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein ZK742.3 {ECO:0000313|EMBL:CCD65779.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein ZK742.3 [Caenorhabditis elegans] col-163 gene40636 1283 1059 439 51 178 43 27.02 21.8804 9.05032 1.0792 3.6871 0.898061 0.000562172998422928 -3.36194991611318 down -- -- -- -- -- -- -- Collagen triple helix repeat (20 copies) Protein COL-163 {ECO:0000313|EMBL:CAD89742.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-163 [Caenorhabditis elegans] C47E12.9 gene19164 33 32 20 13 9 8 4.98559 4.60152 2.94715 1.94404 1.31741 1.27411 0.00649399650234948 -1.51247646445317 down -- -- -- -- -- -- -- -- Protein C47E12.9 {ECO:0000313|EMBL:CAA93103.2} OS=Caenorhabditis elegans PE=4 SV=2 J Translation, ribosomal structure and biogenesis Protein C47E12.9 [Caenorhabditis elegans] clec-74 gene14171 2456 2702 1202 29 37 4 119.2514 128.0606 56.2345 1.418118 1.767469 0.235738392672 1.31448895160207e-13 -6.51658190636543 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-74 {ECO:0000313|EMBL:CCD71968.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-74 [Caenorhabditis elegans] C16E9.1 gene43065 613 544 493 1053 1174 1344 17.71789114 16.9807500012471 15.133987 31.8927200000301 34.2359647 40.39146 5.62549133460179e-07 1.1067342899479 up -- -- -- -- -- [WV] Extracellular structures;; Defense mechanisms von Willebrand factor type A domain;; von Willebrand factor type A domain;; VWA domain containing CoxE-like protein Protein C16E9.1 {ECO:0000313|EMBL:CCD64766.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C16E9.1 [Caenorhabditis elegans] F40G12.10 gene38214 84 105 148 59 52 39 3.85517 4.95792 6.90976 2.82919 2.46764 1.87939 0.00894336767303607 -1.1755059805671 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein F40G12.10 {ECO:0000313|EMBL:CAB01189.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F40G12.10 [Caenorhabditis elegans] C33G8.13 gene35160 705 599 308 30 82 18 53.1706 45.3715 23.2993 2.29279 6.2663 1.40732 2.54236746319392e-06 -3.64068580244845 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C33G8.13 {ECO:0000313|EMBL:CCD66537.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C33G8.13 [Caenorhabditis elegans] K08D8.6 gene20295 2562 2994 2165 951 801 608 101.762157 122.5387844721 83.822959735047 38.8071496631368 32.0840875537 24.9282200892 6.38222885806506e-12 -1.71909090151475 down -- -- -- -- -- -- -- CUB-like domain Protein K08D8.6, isoform a {ECO:0000313|EMBL:CAA97438.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K08D8.6 [Caenorhabditis elegans] gst-32 gene9358 10 10 4 26 27 42 1.5228 1.47052 0.677637 4.04452 3.90049 6.30105 0.000219369181548813 1.97750493435136 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain Protein GST-32 {ECO:0000313|EMBL:CAB97240.2} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein GST-32 [Caenorhabditis elegans] thn-2 gene20130 197 141 299 2244 2826 4271 21.8098511816 14.923452 31.45762 244.8173 293.682 446.2924 6.92880245633049e-09 3.86942456581724 up -- -- -- -- -- -- -- Thaumatin family Protein THN-2 {ECO:0000313|EMBL:CAA94600.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein THN-2 [Caenorhabditis elegans] aco-2 gene11602 17876 16468 17494 36989 35627 38613 376.841 347.703 365.707 782.995 754.768 814.545 4.29418540845771e-07 1.09399600508977 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; K01681|0|cbr:CBG22943|Cbr-aco-2; C. briggsae CBR-ACO-2 protein; K01681 aconitate hydratase [EC:4.2.1.3] (A) Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [CE] Energy production and conversion;; Amino acid transport and metabolism Aconitase family (aconitate hydratase);; Aconitase C-terminal domain CBN-ACO-2 protein {ECO:0000313|EMBL:EGT51594.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein ACO-2, isoform a [Caenorhabditis elegans] C17F4.8 gene5330 20 23 20 61 46 45 0.642784 2.389594 1.556622 2.921304 1.839205 2.80733 0.00674555519897645 1.26204454499405 up -- -- Molecular Function: protein binding (GO:0005515);; Biological Process: protein homooligomerization (GO:0051260);; -- -- [P] Inorganic ion transport and metabolism BTB/POZ domain;; BTB/POZ domain Protein C17F4.8 {ECO:0000313|EMBL:CCD64912.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C17F4.8 [Caenorhabditis elegans] W03G1.2 gene13329 32 43 41 19 14 14 1.61761 2.14963 2.04533 0.993127 0.73452 0.721861 0.00957751694582355 -1.31162369133534 down -- -- -- -- -- -- -- Protein of unknown function (DUF851) Protein W03G1.2 {ECO:0000313|EMBL:CCD69082.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W03G1.2 [Caenorhabditis elegans] fbxa-79 gene9705 462 562 460 247 212 253 40.9197 49.3076 40.8155 22.49954 18.71417 22.89136 4.46797427574646e-05 -1.06710195976776 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-79 {ECO:0000313|EMBL:CCD73898.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein FBXA-79 [Caenorhabditis elegans] srd-64 gene9811 822 958 859 420 388 330 38.0650656557 42.1176600000005 34.7811310664621 20.188501 20.203549 18.5471330585 1.13976486844008e-07 -1.22162073732492 down -- -- -- K08473|0|cel:CELE_Y22D7AR.8|srd-64; Protein SRD-64; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Srd Protein SRD-64 {ECO:0000313|EMBL:CCD73763.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein SRD-64 [Caenorhabditis elegans] Y57E12B.4 gene35131 1279 1273 497 90 214 142 77.506876000002 73.013311 27.3780570665307 4.98284915003381 12.0569021700011 8.0456068822132 0.00113037096053376 -2.78033465896897 down -- -- -- -- -- -- -- -- Protein Y57E12B.4 {ECO:0000313|EMBL:CCD72908.1} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein Y57E12B.4 [Caenorhabditis elegans] C45E5.1 gene16145 9 15 11 350 381 261 0.724831 1.20439 0.850275 27.2287 29.008 20.4531 7.55146593261418e-34 4.81709536661496 up [G] Carbohydrate transport and metabolism -- -- -- [P] Inorganic ion transport and metabolism Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Mitochondrial PGP phosphatase Protein C45E5.1 {ECO:0000313|EMBL:CCD67369.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C45E5.1 [Caenorhabditis elegans] T20D4.12 gene33917 481 434 180 15 14 31 51.86048 44.3074 20.52965 1.3729 1.3170276 3.6907 9.49360668444953e-06 -4.19663116611579 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T20D4.12 {ECO:0000313|EMBL:CCD62941.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein T20D4.12 [Caenorhabditis elegans] klo-2 gene9982 143 138 133 65 54 56 5.970378 5.530528 5.516508 2.714347 2.334445 2.603703 0.000352769332113315 -1.25048102068719 down [G] Carbohydrate transport and metabolism Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolase family 1 Protein KLO-2 {ECO:0000313|EMBL:CCD68636.1} OS=Caenorhabditis elegans PE=3 SV=1 T Signal transduction mechanisms Protein KLO-2 [Caenorhabditis elegans] bli-6 gene17347 3188 3780 3868 1843 1369 1226 199.469 220.62 229.195 111.725 81.0351 73.0777 2.68599320763735e-11 -1.29642696226979 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein BLI-6 {ECO:0000313|EMBL:CCD74181.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein BLI-6 [Caenorhabditis elegans] C46H11.2 gene1091 316 372 239 652 606 715 16.48197 18.98375 12.264035 33.62449 31.815312 37.534737 1.09333611333909e-05 1.08203192070629 up -- -- Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD-NAD(P)-binding;; HI0933-like protein;; L-lysine 6-monooxygenase (NADPH-requiring);; FAD binding domain;; Glucose inhibited division protein A;; Pyridine nucleotide-disulphide oxidoreductase;; Thi4 family;; NAD(P)-binding Rossmann-like domain;; Lycopene cyclase protein;; Putative NAD(P)-binding;; FAD binding domain Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein C46H11.2 [Caenorhabditis elegans] Y54G2A.45 gene13851 2008 2284 1274 671 501 306 164.6750231855 180.7550116092 101.47900904671 56.61600460024 39.6631161683 24.70190955845 5.99475410317692e-05 -1.92345054017033 down -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein Y54G2A.45, isoform a {ECO:0000313|EMBL:CCD83539.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein Y54G2A.45 [Caenorhabditis elegans] C35A5.3 gene36525 419 398 309 1249 1437 1571 25.217828481 24.422191513 18.661678565 76.98616593 87.960170169 96.813244163 2.32803604466778e-19 1.91135982266396 up -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein C35A5.3 {ECO:0000313|EMBL:CAA94906.3} OS=Caenorhabditis elegans PE=4 SV=3 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C35A5.3 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_607 55 61 59 114 155 158 2.86598 3.181 3.01729 5.98741 8.05982 8.29006 0.000225626731449307 1.28059114718733 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-271 {ECO:0000313|EMBL:CAB07282.2} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones PREDICTED: hormone receptor 4 [Musca domestica] nhr-271 gene39237 2 0 0 21 21 24 0.11985699698 0 0.06499612829493 1.193161103 1.12316985 1.6954459441413 1.03055412420153e-09 5.03204158686556 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-271 {ECO:0000313|EMBL:CAB07282.2} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones Protein NHR-271 [Caenorhabditis elegans] ZK1248.5 gene6268 58 92 81 36 29 41 4.2755 6.81704 5.97964 2.69987 2.2044 3.13157 0.00649371352090543 -1.13059857029071 down -- -- -- -- -- -- -- Protein of unknown function (DUF1248) Protein ZK1248.5 {ECO:0000313|EMBL:CCD72507.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK1248.5 [Caenorhabditis elegans] best-24 gene11572 231 296 274 728 1031 1474 6.09385623700011 8.04077293 7.41535891812942 19.85820434 28.1461770000809 40.25972419 0.000757113211917777 2.00789063725333 up -- -- -- -- -- [R] General function prediction only Bestrophin, RFP-TM, chloride channel Putative uncharacterized protein {ECO:0000313|EMBL:EFP04239.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein BEST-24 [Caenorhabditis elegans] dhs-3 gene2064 1218 1150 960 2064 2321 3152 99.3382094160001 94.1318888797 78.719812179 170.178186981 188.026707544 258.646448897 0.00044879122979893 1.17269073284784 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- K15734|0|cbr:CBG04146|Cbr-dhs-3; C. briggsae CBR-DHS-3 protein; K15734 all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] (A) Retinol metabolism (ko00830) [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase Protein DHS-3, isoform b {ECO:0000313|EMBL:CAN86611.1} OS=Caenorhabditis elegans PE=3 SV=1 T Signal transduction mechanisms Protein DHS-3, isoform b [Caenorhabditis elegans] F13D12.6 gene8450 10424 11784 7933 4033 3123 1828 413.6119 455.7082 309.2382 161.1754 121.0362 70.9017 1.31215945677994e-07 -1.75645445359143 down -- -- Molecular Function: serine-type carboxypeptidase activity (GO:0004185);; Biological Process: proteolysis (GO:0006508);; K13289|0|cel:CELE_F13D12.6|F13D12.6; Protein F13D12.6; K13289 cathepsin A (carboxypeptidase C) [EC:3.4.16.5] (A) Lysosome (ko04142) [OE] Posttranslational modification, protein turnover, chaperones;; Amino acid transport and metabolism Serine carboxypeptidase Protein CBG03132 {ECO:0000313|EMBL:CAP23514.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein F13D12.6 [Caenorhabditis elegans] D2023.1 gene37210 191 188 106 373 382 335 21.14073980805 19.3728401444384 12.1895440037555 33.155339842292 26.37523710498 24.5869113961415 2.98186353641865e-05 1.15962478295671 up -- -- Biological Process: sensory perception of chemical stimulus (GO:0007606);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [C] Energy production and conversion C. elegans Sre G protein-coupled chemoreceptor;; Serpentine type 7TM GPCR receptor class ab chemoreceptor Protein D2023.1, isoform f {ECO:0000313|EMBL:CBI63213.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein D2023.1, isoform f [Caenorhabditis elegans] pqn-44 gene1184 8209 7059 8365 3067 2895 5718 247.74706585 203.97806326 256.72046315 85.2426538120079 79.0426455605365 167.31532603 0.000655126257254317 -1.0224527521459 down -- -- -- -- -- [S] Function unknown Domain of unknown function (DUF1693) Protein PQN-44, isoform a {ECO:0000313|EMBL:CCD65444.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein PQN-44, isoform a [Caenorhabditis elegans] ZC376.2 gene38175 120 146 115 268 310 312 3.66916 4.44353 3.453290276 8.2694546262 9.371087 9.899618 2.7817889212863e-05 1.21698432296352 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein ZC376.2, isoform b {ECO:0000313|EMBL:CCG28268.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZC376.2, isoform b [Caenorhabditis elegans] gst-38 gene38929 1262 1306 958 105 84 50 166.601 168.948 126.6 14.401 11.0381 6.64294 1.37409846516606e-36 -3.89297041202444 down -- -- Molecular Function: protein binding (GO:0005515);; K00799|3.36831e-154|cel:CELE_F35E8.8|gst-38; Protein GST-38; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain Protein GST-38 {ECO:0000313|EMBL:CAB04293.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GST-38 [Caenorhabditis elegans] cng-1 gene38508 864 1073 883 89 132 93 20.445272 24.023679 20.42627981 2.4655890839 3.4648102 2.45706254137 5.61405852500717e-40 -3.1738386892401 down -- -- -- -- -- [PT] Inorganic ion transport and metabolism;; Signal transduction mechanisms Cyclic nucleotide-binding domain;; Ion transport protein Protein CNG-1, isoform b {ECO:0000313|EMBL:CAP16270.2} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CNG-1, isoform b [Caenorhabditis elegans] C10H11.7 gene1004 3232 4324 4309 1425 1209 1009 126.237047716 175.8051238512 169.254836000083 56.824722828752 48.4329441190701 40.8170277152 1.69690764827762e-13 -1.71161336057179 down -- -- -- -- -- [U] Intracellular trafficking, secretion, and vesicular transport MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein C10H11.7 [Caenorhabditis elegans] got-2.2 gene42813 5861 5254 5475 12537 13258 15780 231.51174 203.3587035 211.55577325177 493.276246 518.3122132 619.71225 2.11724925104508e-11 1.31845400078687 up [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K14455|0|cbr:CBG05011|Hypothetical protein CBG05011; K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Aminotransferase class I and II Aspartate aminotransferase {ECO:0000256|RuleBase:RU000480} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein GOT-2.2, isoform a [Caenorhabditis elegans] F14F8.8 gene39288 2 0 3 26 49 38 29.2664 0 57.223 585.384 733.734 734.743 2.38437692764872e-09 4.49311413474211 up -- -- -- -- -- -- -- -- Protein F14F8.8 {ECO:0000313|EMBL:CAB07183.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F14F8.8 [Caenorhabditis elegans] ptr-22 gene40119 1702 1976 1496 272 268 420 36.0441296220025 40.7737091343743 30.8283706682932 5.7306560205595 5.5193459539966 8.73529332521922 3.53325476762233e-25 -2.43664034032608 down -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only Patched family;; Sterol-sensing domain of SREBP cleavage-activation Protein PTR-22, isoform a {ECO:0000313|EMBL:CCF23383.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein PTR-22, isoform a [Caenorhabditis elegans] asns-2 gene43802 4792 5294 4504 11373 12842 15643 152.17732803 165.117923669 141.731996112 359.688760144 403.175898786 490.929205439 8.77785546690164e-10 1.44325577331006 up [E] Amino acid transport and metabolism Molecular Function: asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);; Biological Process: asparagine biosynthetic process (GO:0006529);; K01953|0|cbr:CBG15441|Hypothetical protein CBG15441; K01953 asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] (A) Alanine, aspartate and glutamate metabolism (ko00250) [E] Amino acid transport and metabolism Asparagine synthase;; Glutamine amidotransferase domain;; Glutamine amidotransferase domain;; Aluminium induced protein;; Glutamine amidotransferases class-II Asparagine synthetase {ECO:0000256|PIRNR:PIRNR001589} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ASNS-2, isoform a [Caenorhabditis elegans] Y105C5A.24 gene28491 255 272 204 430 469 580 8.304479 8.745683 6.512058 13.800201 14.863076731 18.38429 0.000128965162684956 1.00971502918038 up [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; K04427|0|cel:CELE_Y105C5A.24|Y105C5A.24; Protein Y105C5A.24; K04427 mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] (A) MAPK signaling pathway (ko04010);; Wnt signaling pathway (ko04310) [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein Y105C5A.24 {ECO:0000313|EMBL:CAB55004.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y105C5A.24 [Caenorhabditis elegans] amt-4 gene42164 659 695 582 373 295 117 26.38202 28.00469 23.65317 15.5149 11.9506 4.73326 2.18988778324267e-05 -1.31290092315261 down [P] Inorganic ion transport and metabolism Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; -- -- [P] Inorganic ion transport and metabolism Ammonium Transporter Family Protein AMT-4 {ECO:0000313|EMBL:CCD63266.1} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein AMT-4 [Caenorhabditis elegans] F17E9.2 gene18545 282 221 180 57 103 74 15.1521439865 11.7579627 9.497765 3.48483898 9.215129 4.756998032 3.34708074620561e-05 -1.55253218507846 down -- -- -- -- -- -- -- -- Protein F17E9.2 {ECO:0000313|EMBL:CCD68526.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F17E9.2 [Caenorhabditis elegans] dod-17 gene20336 3307 3665 1738 941 589 149 235.697 262.339 123.398 69.0468 42.1651 10.7805 0.000378648698287755 -2.38783768442037 down -- -- -- -- -- -- -- CUB-like domain Protein DOD-17 {ECO:0000313|EMBL:CAB03521.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein DOD-17 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_579 76 76 104 46 33 32 2.25916 2.29763 3.10175 1.4165 1.01087 0.995749 0.0023992919715327 -1.21385555488165 down -- -- -- -- -- -- -- -- Protein K12B6.8 {ECO:0000313|EMBL:CCD70374.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown -- ttr-12 gene40640 25 44 34 17 2 14 6.30799526477 10.0361141847 8.1656856799 4.40398104128 0.64486614323 3.54390899544 0.00652505886525682 -1.65109353909688 down -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-12, isoform a {ECO:0000313|EMBL:CAB04401.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TTR-12, isoform a [Caenorhabditis elegans] grl-3 gene37002 825 656 357 37 144 29 59.629927 43.854991 24.757482 2.599437174122 8.789443 2.0214450883001 5.11418133455012e-05 -3.13740825502212 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-3 {ECO:0000313|EMBL:CAA98506.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein GRL-3 [Caenorhabditis elegans] C49A9.1 gene17217 11 27 21 53 65 56 0.678372 1.60798 1.26168 3.18385 3.87792 3.39152 0.000420857411746578 1.55402911003657 up -- -- -- -- -- -- -- Protein of unknown function (DUF272) Protein C49A9.1 {ECO:0000313|EMBL:CCD67620.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C49A9.1 [Caenorhabditis elegans] clec-125 gene5460 58 69 37 16 11 1 1.41486 1.71048 0.905053 0.395339 0.273802 0.047268 2.38814126594113e-05 -2.56312692537776 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-125 {ECO:0000313|EMBL:CCD73659.2} OS=Caenorhabditis elegans PE=4 SV=3 T Signal transduction mechanisms Protein CLEC-125 [Caenorhabditis elegans] mltn-7 gene32966 420 313 166 12 60 13 8.891579 6.7023 3.67297 0.2721845 1.2472735637 0.30413 0.000104795631909274 -3.41011579687852 down -- -- -- -- -- -- -- Moulting cycle Putative uncharacterized protein {ECO:0000313|EMBL:EFO95132.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only hypothetical protein CRE_09236 [Caenorhabditis remanei] F14F7.4 gene13025 54 63 70 21 30 24 4.0814044 4.89599 5.51391 1.703825 2.623728 2.008676 0.00225087938155992 -1.32448587464833 down -- -- -- -- -- -- -- -- Protein F14F7.4 {ECO:0000313|EMBL:CAB04110.2} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein F14F7.4 [Caenorhabditis elegans] vap-2 gene44454 411 432 493 104 125 223 17.8187268700004 19.0553174670219 21.7972574232 5.69187700000098 5.39652062800065 9.1703021078928 1.78190674881675e-09 -1.56847141140927 down -- -- -- -- -- [S] Function unknown Cysteine-rich secretory protein family Protein SCL-22 {ECO:0000313|EMBL:CAA92136.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein SCL-22 [Caenorhabditis elegans] T12B3.3 gene18166 534 571 509 994 1108 1232 18.87576 22.87643 18.35921 33.1605315 40.704605713 46.4139255899 3.90770336689746e-06 1.03970582819109 up [C] Energy production and conversion Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; -- -- [C] Energy production and conversion Glycerophosphoryl diester phosphodiesterase family;; Putative transmembrane protein (PGPGW) Protein T12B3.3 {ECO:0000313|EMBL:CCD67577.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein T12B3.3 [Caenorhabditis elegans] F56D2.5 gene10847 719 772 610 313 312 260 28.545703 31.919445542 25.50852249 13.11565823 13.00079 10.9747750796246 1.60978668802332e-07 -1.25556833686351 down -- -- Molecular Function: protein binding (GO:0005515);; K11971|0|cel:CELE_F56D2.5|F56D2.5; Protein F56D2.5; K11971 E3 ubiquitin-protein ligase RNF14 [EC:6.3.2.19] (A) -- [O] Posttranslational modification, protein turnover, chaperones IBR domain;; RWD domain Protein F56D2.5 {ECO:0000313|EMBL:CCD63137.1} OS=Caenorhabditis elegans PE=4 SV=2 A RNA processing and modification Protein F56D2.5 [Caenorhabditis elegans] aldo-2 gene10953 11334 10198 11927 21802 21863 25481 621.05286297 540.61543602 644.6049 1199.43466 1183.0069 1378.4088 6.93972666772123e-07 1.04026835473225 up [G] Carbohydrate transport and metabolism Molecular Function: fructose-bisphosphate aldolase activity (GO:0004332);; Biological Process: glycolytic process (GO:0006096);; K01623|0|cbr:CBG09060|Hypothetical protein CBG09060; K01623 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] (A) Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [G] Carbohydrate transport and metabolism Fructose-bisphosphate aldolase class-I Fructose-bisphosphate aldolase {ECO:0000256|RuleBase:RU003994} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 E Amino acid transport and metabolism Protein ALDO-2, isoform a [Caenorhabditis elegans] col-44 gene45434 4224 3474 1515 238 546 449 210.3561 157.9063 69.5859 11.37967 24.97525 20.94931 0.00109511159791957 -2.90845374482937 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-44 {ECO:0000313|EMBL:CAA94136.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-44 [Caenorhabditis elegans] gpdh-1 gene3956 425 282 305 2401 2695 1963 16.54652272271 10.2778660003264 11.4724696076 94.365153 102.0703114764 72.518379 7.0828386805237e-27 2.79374817039021 up [C] Energy production and conversion Molecular Function: glycerol-3-phosphate dehydrogenase [NAD+] activity (GO:0004367);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: glycerol-3-phosphate catabolic process (GO:0046168);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; K00006|0|cel:CELE_F47G4.3|gpdh-1; Protein GPDH-1; K00006 glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] (A) Glycerophospholipid metabolism (ko00564) [C] Energy production and conversion NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus;; NADP oxidoreductase coenzyme F420-dependent Glycerol-3-phosphate dehydrogenase [NAD(+)] {ECO:0000256|RuleBase:RU361243} OS=Caenorhabditis elegans PE=3 SV=1 Z Cytoskeleton Protein GPDH-1 [Caenorhabditis elegans] C42D4.13 gene18070 536 461 316 113 158 108 75.2991500000001 58.3668000002898 40.68595 15.811363692 19.031183538 15.014700777 1.27731600287802e-05 -1.80073936578096 down -- -- -- -- -- -- -- -- Protein C42D4.13, isoform a {ECO:0000313|EMBL:CDK13385.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only C42D4.13, isoform a [Caenorhabditis elegans] tmem-135 gene42192 244 299 216 690 629 690 14.01589973508 17.0465400761566 12.03553911 35.4066353 30.6965920004931 35.6108711200018 6.31990127507907e-09 1.39654903139417 up -- -- -- -- -- [S] Function unknown -- Protein TMEM-135 {ECO:0000313|EMBL:CCD68559.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein TMEM-135 [Caenorhabditis elegans] dao-4 gene44216 186 198 181 77 88 46 20.827 21.5285 19.8946 8.78728 9.67773 5.18965 8.17586654280505e-06 -1.42958610545167 down -- -- -- -- -- -- -- -- Protein DAO-4 {ECO:0000313|EMBL:CAA88978.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein DAO-4 [Caenorhabditis elegans] K09E2.1 gene43782 1329 1074 528 30 104 49 21.2639160125007 16.89720324621 8.182417329525 0.47727397348 1.63673986323 0.776502412400006 4.0830366503247e-06 -4.00845030631773 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain Protein K09E2.1 {ECO:0000313|EMBL:CCD69321.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein K09E2.1 [Caenorhabditis elegans] ges-1 gene33260 1215 1138 846 2174 2577 3037 40.67055 38.94049 28.67665 75.43336 87.69963 104.268364 5.89923413163476e-07 1.27657359033921 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; K01044|0|cel:CELE_R12A1.4|ges-1; Protein GES-1; K01044 carboxylesterase 1 [EC:3.1.1.1] (A) Drug metabolism - other enzymes (ko00983) [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family CRE-GES-1 protein {ECO:0000313|EMBL:EFO87676.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein GES-1 [Caenorhabditis elegans] C36H8.1 gene20259 189 204 271 109 94 114 7.5026 7.54182 9.99854 4.0074 3.42076 4.20081 0.000654726106775454 -1.07356827255179 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C36H8.1 [Caenorhabditis elegans] clec-10 gene4317 152 210 221 970 881 738 8.295386 10.9459 11.52358 51.34904 45.94905 39.00844 2.05196283332551e-20 2.14313325345001 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-10 {ECO:0000313|EMBL:CCD62818.1} OS=Caenorhabditis elegans PE=4 SV=2 JK Translation, ribosomal structure and biogenesis;; Transcription Protein CLEC-10 [Caenorhabditis elegans] ugt-53 gene33700 88 111 79 423 484 624 3.81315484969735 4.524521761 3.24778658551 17.537991688 19.62750825979 25.780541315 8.45072526848974e-13 2.45482850083307 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-53 {ECO:0000313|EMBL:CCD71811.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein UGT-53 [Caenorhabditis elegans] cut-6 gene12576 1437 1103 799 286 369 250 46.504984 34.3602472008 25.206792318 9.0096599414284 11.6093600586 7.9636866654 5.74895117553904e-05 -1.89198082542943 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; Zona pellucida-like domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain Protein CUT-6 {ECO:0000313|EMBL:CAA97806.2} OS=Caenorhabditis elegans PE=4 SV=2 TU Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport Protein CUT-6 [Caenorhabditis elegans] R11D1.3 gene37619 145 116 67 6 7 15 15.68451 11.56685 8.35531 0.71594 0.90998 1.527449 1.4594206446531e-06 -3.55624169178053 down -- -- -- -- -- -- -- -- Protein R11D1.3 {ECO:0000313|EMBL:CAA99900.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein R11D1.3 [Caenorhabditis elegans] hrg-7 gene37635 428 547 381 2547 2460 1507 22.983050416 29.4654087 20.2884934057 139.2770730071 132.2850294716 80.69920907552 1.46518347990206e-07 2.25520719933665 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-10, isoform a {ECO:0000313|EMBL:CAA99777.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein ASP-10, isoform a [Caenorhabditis elegans] acs-1 gene34964 1683 1376 1543 3638 2969 2859 38.2714665125893 31.5576186839412 35.3207783831677 83.5120295850027 68.5296326294081 65.6459612772072 2.44174396570453e-07 1.03197989790661 up [IQ] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; -- -- [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Protein ACS-1, isoform a {ECO:0000313|EMBL:CCD71310.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein ACS-1, isoform a [Caenorhabditis elegans] C25G4.8 gene20179 22 27 33 12 9 9 1.32355 1.65753 1.98986 0.736193 0.550309 0.576594 0.00969687782355981 -1.45854172476409 down -- -- -- -- -- -- -- Protein of unknown function (DUF1265) Protein C25G4.8 {ECO:0000313|EMBL:CAA94574.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein C25G4.8 [Caenorhabditis elegans] ZK285.2 gene39000 438 316 162 11 45 19 105.5442 70.0051 37.63636 2.845847 10.43486 4.534097 0.000129754996112679 -3.6173519943497 down -- -- -- -- -- -- -- -- Protein ZK285.2 {ECO:0000313|EMBL:CAE18058.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein ZK285.2 [Caenorhabditis elegans] R01H2.4 gene11311 48 41 30 8 17 13 2.4217222294 1.9804322755 1.3765443709 0.3725803018103 1.041309246 0.602440639 0.000796995332856578 -1.65346932088969 down -- -- -- -- -- -- -- -- Protein R01H2.4 {ECO:0000313|EMBL:CCD69285.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein R01H2.4 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_29 12 37 21 88 89 120 0.584977 1.75352 1.02261 4.25302 4.2377 5.74053 4.27640490777496e-08 2.07911799178145 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; FTH domain Protein FBXA-216 {ECO:0000313|EMBL:CAA21741.3} OS=Caenorhabditis elegans PE=4 SV=3 J Translation, ribosomal structure and biogenesis -- cyp-14A3 gene45302 53 138 133 6 10 2 2.21522 5.7859 5.45557 0.276404 0.426503 0.12235 1.43475709974872e-05 -4.17731185092507 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-14A3 {ECO:0000313|EMBL:CAA90617.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-14A3 [Caenorhabditis elegans] R09E12.9 gene33122 311 672 420 49 65 14 135.824 260.229 171.898 22.9276 26.2829 6.33915 1.05575523408611e-05 -3.46322240158197 down -- -- -- -- -- -- -- Domain of unknown function (DUF4440) Protein R09E12.9 {ECO:0000313|EMBL:CCD63255.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein R09E12.9 [Caenorhabditis elegans] C24B5.4 gene36018 316 271 270 914 937 1036 22.95845 19.21856 19.70517 66.8356 68.1511 75.6035 9.45787405715055e-15 1.74478656863689 up -- -- Cellular Component: nucleus (GO:0005634);; -- -- [S] Function unknown Domain of Unknown Function (DUF1907) Protein C24B5.4 {ECO:0000313|EMBL:CCD61431.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C24B5.4 [Caenorhabditis elegans] H24K24.3 gene33166 2442 2176 2533 4688 4848 5424 193.713924000782 177.359160035156 206.504046484057 403.705859933068 409.95569373 463.9311434315 7.66763983015469e-08 1.05787864448522 up [C] Energy production and conversion Biological Process: oxidation-reduction process (GO:0055114);; K00121|0|cel:CELE_H24K24.3|H24K24.3; Protein H24K24.3, isoform B; K00121 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Carbon metabolism (ko01200);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase Protein CBG17892 {ECO:0000313|EMBL:CAP35434.1} OS=Caenorhabditis briggsae PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein H24K24.3, isoform b [Caenorhabditis elegans] H11E01.2 gene41108 127 128 122 520 649 774 5.241650821 5.250677 4.9072186537 21.4932701297 26.26185454 31.497510082 3.24603323006291e-13 2.35931319182296 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein H11E01.2 {ECO:0000313|EMBL:CCD61776.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein H11E01.2 [Caenorhabditis elegans] pud-4 gene33542 399 376 613 35 19 60 87.4045810919 76.0703519233 130.01499 7.7458078039 4.323465 13.16106 1.57794652326995e-11 -3.61123797513793 down -- -- -- -- -- -- -- -- Protein PUD-4, isoform a {ECO:0000313|EMBL:CCU83358.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms PUD-4, isoform a [Caenorhabditis elegans] F49C12.2 gene18867 19 48 17 475 556 444 1.28113 3.17891 1.15947 31.83346 36.5608 29.8098 1.04607705282266e-44 4.12659333830524 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F49C12.2 {ECO:0000313|EMBL:CAA92507.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49C12.2 [Caenorhabditis elegans] W04C9.9 gene85 14 8 19 51 55 55 0.767838912961422 0.3183927 0.9457545893 2.588604980238 2.7613675 3.2249927387 1.32664755823503e-05 1.96673249716666 up -- -- -- -- -- [G] Carbohydrate transport and metabolism -- Protein W04C9.9 {ECO:0000313|EMBL:CDK13375.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only W04C9.9 [Caenorhabditis elegans] F49C12.5 gene18870 17 15 11 252 286 219 0.628684 0.536705 0.464289 8.934146 10.579909 8.384443 6.85051131891783e-33 4.12944272294319 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein Y97E10B.1 {ECO:0000313|EMBL:CCD70068.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F49C12.5, isoform a [Caenorhabditis elegans] pcca-1 gene43377 7143 6660 7104 16023 16131 17928 149.302319658982 140.799535100005 151.0323519 342.909434 342.019616 377.0254349 3.47671525526598e-10 1.253106727402 up [I] Lipid transport and metabolism Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; K01965|0|cel:CELE_F27D9.5|pcca-1; Protein PCCA-1; K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] (A) Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640) [IE] Lipid transport and metabolism;; Amino acid transport and metabolism Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain;; Biotin-lipoyl like;; D-ala D-ala ligase C-terminus;; ATP-grasp domain;; ATP-grasp domain;; RimK-like ATP-grasp domain CRE-PCCA-1 protein {ECO:0000313|EMBL:EFO82470.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 W Extracellular structures Protein PCCA-1 [Caenorhabditis elegans] pho-13 gene7421 52 80 56 163 136 95 3.40583 5.59717 3.381263 11.03097 8.28047 6.0825 0.00930774085888259 1.05852358417638 up -- -- Molecular Function: acid phosphatase activity (GO:0003993);; -- -- [I] Lipid transport and metabolism Histidine phosphatase superfamily (branch 2) Protein PHO-13, isoform a {ECO:0000313|EMBL:CAA92657.2} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein PHO-13, isoform a [Caenorhabditis elegans] srr-2 gene40197 22 13 29 37 54 62 1.66005 0.956266 2.09906 2.67861 3.98997 4.51213 0.0072905341918815 1.25203700775764 up -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF267 Protein SRR-2 {ECO:0000313|EMBL:CAB04849.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein SRR-2 [Caenorhabditis elegans] F44G3.10 gene39041 105 121 55 230 217 316 31.7096 33.8248 15.8859 72.8757 62.0167 95.4251 0.000144871696922186 1.43357776817605 up -- -- -- -- -- -- -- Tight junction protein, Claudin-like Protein F44G3.10 {ECO:0000313|EMBL:CAB05514.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F44G3.10 [Caenorhabditis elegans] col-123 gene19081 5783 4776 2432 229 725 227 263.809 209.714 108.491 10.3587 32.2103 10.1502 1.25549640069004e-05 -3.46712916213632 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-123 {ECO:0000313|EMBL:CAA94234.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-123 [Caenorhabditis elegans] C17B7.15 gene33899 54 30 25 0 13 5 5.68865 3.03915 2.56311000026556 0.142026 1.841803 0.791408 0.00516156245228303 -2.60296355250304 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein T28A11.2, isoform a {ECO:0000313|EMBL:CCD70561.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T28A11.2, isoform a [Caenorhabditis elegans] F44E7.2 gene34670 715 748 753 6912 7982 6920 33.4110767 74.1074720055002 34.34767122 306.214037017 374.2894795475 324.241691684 6.52511047624432e-63 3.29195185142652 up [G] Carbohydrate transport and metabolism -- K01101|0|cel:CELE_F44E7.2|F44E7.2; Protein F44E7.2; K01101 4-nitrophenyl phosphatase [EC:3.1.3.41] (A) -- [P] Inorganic ion transport and metabolism Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Haloacid dehalogenase-like hydrolase Protein F44E7.2 {ECO:0000313|EMBL:CCD67858.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F44E7.2 [Caenorhabditis elegans] pcp-1 gene11526 1162 1185 804 2060 2016 2326 42.6987260891 44.502566821101 29.461792222 78.548391138753 75.93102533164 88.0531537667003 9.33319359661471e-07 1.01495380183242 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; K01285|0|cel:CELE_ZK112.1|pcp-1; Protein PCP-1; K01285 lysosomal Pro-X carboxypeptidase [EC:3.4.16.2] (A) -- [OR] Posttranslational modification, protein turnover, chaperones;; General function prediction only Serine carboxypeptidase S28;; alpha/beta hydrolase fold CRE-PCP-1 protein {ECO:0000313|EMBL:EFP04208.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein PCP-1 [Caenorhabditis elegans] R08F11.4 gene34044 337 378 367 142 157 117 21.2032 23.8386 23.2728 9.26773 9.90965 7.43096 4.39318977905378e-07 -1.38678116580389 down [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only Biological Process: tRNA modification (GO:0006400);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: tRNA (guanine-N7-)-methyltransferase activity (GO:0008176);; -- -- [IR] Lipid transport and metabolism;; General function prediction only Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Methyltransferase domain;; Methyltransferase small domain;; Putative methyltransferase;; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Protein R08F11.4 {ECO:0000313|EMBL:CCD72309.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein R08F11.4 [Caenorhabditis elegans] mpst-4 gene5864 48 78 70 21 22 41 3.49092 5.63856 5.04242 1.60994 1.61671 3.04447 0.00547213535392937 -1.2273549634514 down [P] Inorganic ion transport and metabolism -- -- -- [V] Defense mechanisms Rhodanese-like domain Protein MPST-6 {ECO:0000313|EMBL:CCD74088.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein MPST-5 [Caenorhabditis elegans] col-175 gene43981 1908 2139 2348 1180 820 850 106.7772836 110.229580002962 129.72287 60.439195396 38.5566271361208 39.880751337623 8.54200557647906e-09 -1.17439674438556 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-175 {ECO:0000313|EMBL:CCD66768.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures COL-175 [Caenorhabditis elegans] W02H3.1 gene44567 11 20 22 100 84 84 2.681866 5.52922 4.17528 23.01811 20.17506 12.13793 3.44808533273372e-09 2.33111039708708 up -- -- -- -- -- -- -- -- Protein W02H3.1, isoform a {ECO:0000313|EMBL:CAR97852.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W02H3.1, isoform a [Caenorhabditis elegans] srd-11 gene37964 31 18 27 67 59 65 0.68947156902 0.42665223213 0.52289768676 3.18388939334 1.13633928661 1.17158289816 0.00221676903393536 1.32151381556933 up -- -- -- K08473|0|cbr:CBG11522|Cbr-srd-11; C. briggsae CBR-SRD-11 protein; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Str Protein SRD-11, isoform a {ECO:0000313|EMBL:CAB01205.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein SRD-11, isoform a [Caenorhabditis elegans] lipl-2 gene36235 1583 1629 1398 338 496 735 87.0921 90.7658 79.64481 19.22431 26.91912 40.88773 2.83705473638625e-13 -1.56031995406448 down [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 K Transcription Protein LIPL-2 [Caenorhabditis elegans] col-102 gene13353 29416 21694 10149 1031 3309 2126 841.513 611.469 292.179 30.0613 93.0851 59.6306 0.000738539469834853 -3.25077981504029 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-102 {ECO:0000313|EMBL:CCD63291.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-102 [Caenorhabditis elegans] gipc-1 gene10639 495 573 657 297 271 290 30.9377 35.9382 41.3955 19.1233 17.1675 18.3176 6.67123452143551e-05 -1.01470788134927 down -- -- -- -- -- [TU] Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport -- Protein GIPC-1 {ECO:0000313|EMBL:CCD66775.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein GIPC-1 [Caenorhabditis elegans] Y54G2A.49 gene13869 62 113 98 34 18 29 16.26950267847 26.74125219 24.1875285053 9.188649936 4.527020421471 7.54919267067 0.00025522028136869 -1.7607372536599 down -- -- -- -- -- -- -- -- Protein Y54G2A.49, isoform b {ECO:0000313|EMBL:CDH92959.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Y54G2A.49, isoform b [Caenorhabditis elegans] far-4 gene37756 10 8 2 49 67 103 1.30272 1.01665 0.345883 6.22983 8.16268 12.9671 1.32664755823503e-05 3.4455147972718 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein FAR-4 {ECO:0000313|EMBL:CAB01421.1} OS=Caenorhabditis elegans PE=4 SV=1 TZ Signal transduction mechanisms;; Cytoskeleton Protein FAR-4 [Caenorhabditis elegans] grd-7 gene43196 1810 1470 589 110 217 179 30.38337 23.13719 9.057688 1.690931 3.422134 2.726230314 0.00250638114671778 -2.94219956523482 down -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase;; Ground-like domain Protein GRD-7 {ECO:0000313|EMBL:CCD71363.1} OS=Caenorhabditis elegans PE=1 SV=2 C Energy production and conversion Protein GRD-7 [Caenorhabditis elegans] clec-67 gene14160 7436 8105 5612 2041 1568 1588 306.3514 319.5725 219.9806 81.75589 61.457303517 63.167162736 8.64649223633303e-13 -2.03398882085083 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-67 {ECO:0000313|EMBL:CCD70720.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-67 [Caenorhabditis elegans] ZK1193.2 gene40825 727 647 634 1316 1301 1436 9.8230811829 8.0927779648 8.2603223973 17.2090225005 15.4721531967328 14.88394076442 4.61127987195828e-06 1.00571965250471 up -- -- -- -- -- -- -- von Willebrand factor type A domain;; Lectin C-type domain;; von Willebrand factor type A domain;; Human growth factor-like EGF Protein ZK1193.2 {ECO:0000313|EMBL:CCD71634.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK1193.2 [Caenorhabditis elegans] rol-1 gene8576 3038 3374 3644 1699 1155 1117 91.8957 95.0219 102.1901 48.2738 32.7755 31.77233 4.63452455699016e-12 -1.34921658618557 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein ROL-1 {ECO:0000313|EMBL:CAB55014.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ROL-1 [Caenorhabditis elegans] pals-30 gene23652 30 29 21 12 5 8 1.3328 1.3335 0.953421 0.555451 0.248349 0.394541 0.00277873123940818 -1.68818632973481 down -- -- -- -- -- -- -- -- Protein Y57G11B.1 {ECO:0000313|EMBL:CAB16502.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y57G11B.1 [Caenorhabditis elegans] spe-11 gene1163 300 376 395 170 167 191 14.6721551965 17.437927009 333.465053164 10.02942644375 121.6268938816 9.05741201738 0.000275162313392332 -1.02708113304243 down -- -- -- -- -- -- -- -- CRE-SPE-11 protein {ECO:0000313|EMBL:EFP12555.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 G Carbohydrate transport and metabolism Protein SPE-11 [Caenorhabditis elegans] clec-265 gene41584 5591 8115 4960 1183 847 462 376.976 527.072 318.769 77.6083 54.9511 30.4489 1.30904155376645e-09 -2.91537626062013 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; UL45 protein Protein CLEC-265 {ECO:0000313|EMBL:CCD66488.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-265 [Caenorhabditis elegans] F23D12.11 gene45704 41 26 34 79 101 71 101.09 57.8966 82.9143 247.933 235.635 199.919 0.00108075450252344 1.30544173194401 up -- -- -- -- -- -- -- -- Protein F23D12.11 {ECO:0000313|EMBL:CAZ65487.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F23D12.11 [Caenorhabditis elegans] ZK596.1 gene19521 481 529 327 1077 1206 1119 56.8210876903 57.830993 36.3122145693 127.9727061991 135.428921427 129.4681 1.09782162459524e-09 1.33950751836227 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein ZK596.1 {ECO:0000313|EMBL:CAA93430.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK596.1 [Caenorhabditis elegans] cpr-4 gene35001 6640 5799 6139 19619 21324 24096 393.197 330.858 353.019 1152.263 1224.871 1369.876 8.71310792045875e-20 1.80069185846298 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_F44C4.3|cpr-4; Protein CPR-4; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease CBN-CPR-4 protein {ECO:0000313|EMBL:EGT47019.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 K Transcription Protein CPR-4 [Caenorhabditis elegans] nhr-155 gene33030 86 112 119 22 21 10 5.633254828 7.2566394014 7.552063774 1.484849174 1.3727783541 0.69064366 1.23662346546632e-11 -2.58924470263364 down -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-155 {ECO:0000313|EMBL:CCD64461.1} OS=Caenorhabditis elegans PE=3 SV=1 K Transcription Protein NHR-155 [Caenorhabditis elegans] C33D3.3 gene44357 54 60 70 144 102 136 2.7499025733 2.876576466 3.343870071 7.239886112 5.122493768 7.190356852 0.00417308089210633 1.04635046062635 up -- -- -- -- -- -- -- -- Protein C33D3.3 {ECO:0000313|EMBL:CAA90027.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C33D3.3 [Caenorhabditis elegans] col-172 gene42961 1091 953 480 190 286 243 43.1074 37.2943000000002 18.94188 7.65629 11.67677 9.65544 0.00531067125139227 -1.81943131505598 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-172, isoform a {ECO:0000313|EMBL:CCD68212.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-172, isoform a [Caenorhabditis elegans] C33H5.1 gene18344 7 12 5 143 197 150 0.543828 0.905462 0.417431 10.8813 14.6682 11.3236 4.68604891446933e-28 4.34419733905104 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C33H5.1 {ECO:0000313|EMBL:CCD66585.1} OS=Caenorhabditis elegans PE=4 SV=3 I Lipid transport and metabolism Protein C33H5.1 [Caenorhabditis elegans] W02G9.4 gene33642 1024 1014 584 280 346 328 87.77008025 81.4885736273 47.3502977024 23.5347255696 28.1555556337 27.3220116263 0.000925102199227086 -1.46636660884781 down -- -- -- -- -- -- -- CUB domain Protein W02G9.4 {ECO:0000313|EMBL:CCD74272.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein W02G9.4 [Caenorhabditis elegans] K09F6.5 gene4972 16 10 13 46 41 75 0.907833 0.552985 0.702818 2.57915 2.26194 4.14964 0.000761847411938343 2.04788953370607 up -- -- -- -- -- -- -- -- Protein K09F6.5 {ECO:0000313|EMBL:CCD61652.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K09F6.5 [Caenorhabditis elegans] dod-21 gene20318 6329 8090 6186 373 290 223 438.278 559.729 421.23 25.8876 20.1687 15.6104 1.98648863412992e-52 -4.54867772044019 down -- -- -- -- -- -- -- CUB-like domain Protein C32H11.9 {ECO:0000313|EMBL:CAB05135.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C32H11.9 [Caenorhabditis elegans] K11H12.3 gene13373 42 52 43 9 3 0 2.486511 3.66975 2.300008 0.40717 0.2040503 0 3.05523074030155e-11 -3.52791121352134 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein K11H12.3 {ECO:0000313|EMBL:CCD70972.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein K11H12.3 [Caenorhabditis elegans] his-70 gene10348 28 37 48 13 16 10 10.7131 12.4937 17.1227 5.42509 5.84053 4.03619 0.00215873513398801 -1.54177225933123 down [B] Chromatin structure and dynamics Molecular Function: DNA binding (GO:0003677);; -- -- [B] Chromatin structure and dynamics Core histone H2A/H2B/H3/H4 Histone H3 {ECO:0000256|RuleBase:RU004471} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 L Replication, recombination and repair Protein HIS-70 [Caenorhabditis elegans] ilys-3 gene13759 59 51 49 134 191 266 16.46526 14.37653 10.09607 31.9222 48.709 64.4684 0.000891434479164964 1.88835897328424 up -- -- Molecular Function: lysozyme activity (GO:0003796);; -- -- -- -- Destabilase Protein ILYS-3 {ECO:0000313|EMBL:CCD65531.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ILYS-3 [Caenorhabditis elegans] R02E4.3 gene41975 58 49 53 15 31 24 165.653 130.42 153.432 58.0457 87.3657 80.6267 0.0092556940152107 -1.19866039191492 down -- -- -- -- -- -- -- -- Protein R02E4.3 {ECO:0000313|EMBL:CCD69113.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein R02E4.3 [Caenorhabditis elegans] col-49 gene616 1643 1835 1952 921 638 585 105.636 110.837 123.115 58.4244 39.7064 36.7771 5.7628533797614e-11 -1.34946643404005 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-49 {ECO:0000313|EMBL:CCD67358.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein COL-49 [Caenorhabditis elegans] rhr-1 gene34544 5254 6354 5743 2211 1911 1597 230.5014 273.9213 244.05127 97.2965768 83.33262 68.44449 2.88110557013662e-17 -1.609533194114 down [P] Inorganic ion transport and metabolism Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; K06580|0|cel:CELE_F08F3.3|rhr-1; Protein RHR-1; K06580 ammonium transporter Rh (A) -- [UR] Intracellular trafficking, secretion, and vesicular transport;; General function prediction only Ammonium Transporter Family Protein RHR-1 {ECO:0000313|EMBL:CCD65593.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein RHR-1 [Caenorhabditis elegans] H23L24.4 gene18651 945 1456 1667 135 163 120 37.8213200466012 57.1484600000003 64.7169500000003 4.4379458918 7.054933 4.15329239 2.23448624286668e-11 -3.28942854809979 down -- -- Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srw Protein H23L24.4 {ECO:0000313|EMBL:CCD68983.1} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein H23L24.4 [Caenorhabditis elegans] F59B1.8 gene34009 387 470 431 222 244 94 19.98191 24.11964 22.13378 11.89207 12.59938 4.91506 2.64471307677467e-05 -1.21067798855833 down -- -- -- -- -- -- -- Protein of unknown function (DUF1679);; Ecdysteroid kinase;; Phosphotransferase enzyme family Protein F59B1.8 {ECO:0000313|EMBL:CCD72122.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms protein F59B1.8 [imported] - Caenorhabditis elegans F11C7.7 gene46658 69 120 50 197 253 298 47.08758 80.3046 36.27922 159.5435 176.142 233.915 2.14523067380532e-05 1.63944287427787 up -- -- -- -- -- -- -- Thrombospondin type 1 domain Protein F11C7.7 {ECO:0000313|EMBL:CCD66917.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F11C7.7 [Caenorhabditis elegans] K02E11.6 gene38197 120 156 103 69 50 65 51.745921248 63.028169 44.367546 31.5129007 18.170812 30.70371 0.00403569206063938 -1.05065777711691 down -- -- -- -- -- -- -- -- Protein K02E11.6 {ECO:0000313|EMBL:CAB01221.2} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein K02E11.6 [Caenorhabditis elegans] aagr-1 gene18552 1993 2059 1692 6084 7062 9710 40.76815 42.4636319 34.75968 125.39853 145.3277 198.4189 5.17226105002511e-07 1.98607148455697 up [G] Carbohydrate transport and metabolism Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; K01187|0|cel:CELE_D2096.3|aagr-1; Protein AAGR-1; K01187 alpha-glucosidase [EC:3.2.1.20] (A) Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500) [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 31;; Trefoil (P-type) domain;; Galactose mutarotase-like Protein AAGR-1 {ECO:0000313|EMBL:CCD68508.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein AAGR-1 [Caenorhabditis elegans] F48D6.4 gene42030 1638 1603 1601 3704 4030 4603 570.36416151 541.53303464 543.234901413 1298.049426737 1372.6464 1709.244 3.77764388585987e-12 1.34243533204546 up -- -- -- -- -- -- -- -- Protein F48D6.4, isoform a {ECO:0000313|EMBL:CCD67848.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein F48D6.4, isoform a [Caenorhabditis elegans] his-60 gene18221 36 35 45 14 13 12 38.404 34.0905 48.7316 18.578 13.3513 14.3788 0.00152159282481401 -1.58016434223682 down [B] Chromatin structure and dynamics Biological Process: DNA-templated transcription, initiation (GO:0006352);; K11254|1.53329e-51|spu:752187|histone H4-like; K11254 histone H4 (A) -- [B] Chromatin structure and dynamics Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; TATA box binding protein associated factor (TAF) Histone H4 {ECO:0000256|RuleBase:RU000528} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 B Chromatin structure and dynamics hypothetical protein CRE_08190 [Caenorhabditis remanei] E02C12.6 gene36076 17 40 23 57 85 57 0.942781 2.16404 1.25591 3.16814 4.64339 3.1503 0.00529277476944503 1.3080026694482 up -- -- -- -- -- -- -- Protein of unknown function (DUF1679);; Ecdysteroid kinase;; Phosphotransferase enzyme family;; Fructosamine kinase Protein E02C12.6 {ECO:0000313|EMBL:CCD68591.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein E02C12.6 [Caenorhabditis elegans] ugt-20 gene16963 490 732 683 168 148 104 20.3067 31.0918 28.3477 7.07423 6.27326 4.44647 1.01133415866436e-11 -2.18964641986317 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-20 {ECO:0000313|EMBL:CCD72379.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein UGT-20 [Caenorhabditis elegans] F35F10.5 gene33875 372 334 149 13 3 21 65.5319 54.0616 24.43394 2.15616 0.469354 4.036526 6.06821492381239e-07 -4.53815243772589 down -- -- -- -- -- -- -- -- Protein F35F10.5 {ECO:0000313|EMBL:CCD64818.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F35F10.5 [Caenorhabditis elegans] scl-1 gene20356 321 309 124 14 40 29 42.9756 38.6298 15.8686 1.91913 5.12178 3.79625 0.000291667333292875 -3.18991256452281 down [S] Function unknown -- -- -- [S] Function unknown Cysteine-rich secretory protein family Protein SCL-1 {ECO:0000313|EMBL:CAA94348.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein SCL-1 [Caenorhabditis elegans] Y105C5B.14 gene28918 28 25 31 4 5 1 4.01934 3.38838 4.37008 0.674541 0.759722 0.269446 2.71651677058768e-07 -3.07984985362839 down -- -- -- -- -- -- -- -- Protein Y105C5B.14 {ECO:0000313|EMBL:CAB60318.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only hypothetical protein Y105C5B.k - Caenorhabditis elegans lipl-8 gene38414 119 132 55 3 24 12 7.92944 8.89231 3.67366 0.259582 1.62087 0.853918 0.000271613576846051 -2.97723469876614 down [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 I Lipid transport and metabolism hypothetical protein Y50E8A.g - Caenorhabditis elegans swt-7 gene34421 2315 2618 2334 1370 1125 995 352.031 378.6236 338.9205 206.6405 163.5382 146.8152 1.584772171747e-07 -1.06666394772884 down -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only Sugar efflux transporter for intercellular exchange Sugar transporter SWEET {ECO:0000256|RuleBase:RU910715} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein SWT-7 [Caenorhabditis elegans] daao-1 gene13795 86 93 79 174 185 185 3.705345 3.490765 3.261709 8.03009 8.05539 7.1929 0.00128476422009797 1.06882096064057 up [E] Amino acid transport and metabolism Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00273|0|cel:CELE_Y69A2AR.5|daao-1; Protein DAAO-1; K00273 D-amino-acid oxidase [EC:1.4.3.3] (A) Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330);; D-Arginine and D-ornithine metabolism (ko00472);; Peroxisome (ko04146) [E] Amino acid transport and metabolism FAD dependent oxidoreductase Putative uncharacterized protein {ECO:0000313|EMBL:EGT48636.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein DAAO-1 [Caenorhabditis elegans] F32G8.2 gene36547 352 273 167 11 59 22 11.6670487 9.62105 5.85796 0.3796855461 2.09137 0.7562489441 7.85879293360039e-06 -3.11212462413193 down -- -- -- -- -- -- -- -- Protein F32G8.2 {ECO:0000313|EMBL:CAA96646.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein F32G8.2 [Caenorhabditis elegans] C31H1.5 gene16261 50 80 94 30 32 32 4.44837 7.02528 8.17803 2.67356 2.83947 2.92343 0.00541257854416165 -1.25901701909846 down -- -- -- -- -- -- -- -- Protein C31H1.5 {ECO:0000313|EMBL:CCD64150.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C31H1.5 [Caenorhabditis elegans] asp-14 gene42880 43236 50182 28739 5866 4956 4003 2113.462321886 2349.899239478 1300.241663 196.09820734 162.79274982 117.10805225 1.95621920632673e-10 -3.05190027895981 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease Protein ASP-14 {ECO:0000313|EMBL:CCD72625.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ASP-14 [Caenorhabditis elegans] T25B2.2 gene42767 271 347 388 140 149 200 11.894355 14.644597651779 15.1491065024699 5.88260687717003 4.619279655 6.55343790543193 0.000250089844002256 -1.04658492958139 down -- -- -- -- -- -- -- -- Protein T25B2.2, isoform a {ECO:0000313|EMBL:CCD66693.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T25B2.2, isoform a [Caenorhabditis elegans] nstp-7 gene33044 25 22 27 5 1 0 1.90494 1.64926 2.02004 0.436494 0.137996 0.0726308 4.41368600615715e-08 -3.64037472717865 down [GER] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [G] Carbohydrate transport and metabolism Nucleotide-sugar transporter;; Multidrug resistance efflux transporter;; EamA-like transporter family;; Triose-phosphate Transporter family Protein NSTP-7 {ECO:0000313|EMBL:CCD64474.2} OS=Caenorhabditis elegans PE=4 SV=2 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein NSTP-7 [Caenorhabditis elegans] col-138 gene32562 1317 1293 1575 748 508 493 88.5687 83.9342 102.692 51.7521 33.0897 32.2451 3.12158914358537e-09 -1.26742476647476 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-138 {ECO:0000313|EMBL:CAM36330.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-138 [Caenorhabditis elegans] tag-38 gene35999 229 281 239 67 65 55 9.36355 11.6964 9.86286 2.844581 2.710668 2.301829 1.92298506371827e-11 -2.00989125522749 down [E] Amino acid transport and metabolism Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; -- -- [E] Amino acid transport and metabolism Pyridoxal-dependent decarboxylase conserved domain;; Aminotransferase class-V;; DegT/DnrJ/EryC1/StrS aminotransferase family Protein TAG-38 {ECO:0000313|EMBL:CCD61417.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein TAG-38 [Caenorhabditis elegans] C50F7.5 gene18305 1226 1189 988 2992 3351 3662 81.4288 69.7419 59.7792 188.032 206.422 228.079 1.42563483686071e-15 1.54862185734798 up -- -- -- -- -- -- -- -- Protein C50F7.5 {ECO:0000313|EMBL:CCD67453.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown hypothetical protein C50F7.7 - Caenorhabditis elegans NA Caenorhabditis_elegans_newGene_541 54 37 66 6 3 4 0.961151 0.65565 1.14005 0.115964 0.064977 0.0853966 5.38949643524742e-10 -3.60316629013413 down -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Srz Protein SRZ-32 {ECO:0000313|EMBL:CCD62859.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only -- lys-6 gene19811 0 1 6 35 46 63 0 0.274345 0.956302 5.29324 6.83857 9.46795 8.51797363061687e-10 4.36122334182459 up -- -- Molecular Function: lysozyme activity (GO:0003796);; Biological Process: peptidoglycan catabolic process (GO:0009253);; Biological Process: cell wall macromolecule catabolic process (GO:0016998);; -- -- -- -- Glycosyl hydrolases family 25 Protein LYS-6 {ECO:0000313|EMBL:CAA97801.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein LYS-6 [Caenorhabditis elegans] oac-6 gene39127 2861 3036 2755 1275 1260 1348 81.242084 83.39032 74.15146981 35.35859037 34.29326027 37.33339 4.7538574896919e-09 -1.16327849708814 down -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-6 {ECO:0000313|EMBL:CAB05687.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein OAC-6 [Caenorhabditis elegans] T20G5.12 gene12393 134 128 52 6 28 7 17.4666 16.4386 6.75088 0.874113 3.6794 1.00288 0.00105900767479801 -2.94424973325032 down -- -- -- -- -- -- -- DB module Protein T20G5.12 {ECO:0000313|EMBL:CAA83014.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein T20G5.12 [Caenorhabditis elegans] F41E6.7 gene35770 64 50 41 107 135 165 5.15821 3.75124484462 3.188052 8.1477863 10.565716 13.8806 7.20367816256857e-05 1.38582504150197 up -- -- -- -- -- -- -- -- Protein F41E6.7 {ECO:0000313|EMBL:CCD64099.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein F41E6.7 [Caenorhabditis elegans] F26G1.3 gene5819 109 89 44 3 4 6 45.6867 33.699 17.262 1.6787 1.81025 2.84862 4.09341043113311e-06 -4.22523890784106 down -- -- -- -- -- -- -- Transthyretin-like family Protein F26G1.3 {ECO:0000313|EMBL:CCD65846.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F26G1.3 [Caenorhabditis elegans] vit-2 gene42324 32319 30497 44320 93320 98907 115998 281.67807 258.67898 377.02247 797.8635 845.603 989.7904 3.09965477408696e-11 1.5182494062239 up -- -- Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; -- -- [I] Lipid transport and metabolism Lipoprotein amino terminal region;; Domain of unknown function (DUF1943);; von Willebrand factor type D domain Protein VIT-2, isoform b {ECO:0000313|EMBL:CCD65571.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein VIT-2, isoform a [Caenorhabditis elegans] clec-8 gene8725 84 98 94 279 321 390 4.42399 4.95765 4.76452 14.6642 16.1078 19.7209 5.33010867317646e-11 1.83646858806186 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-8 {ECO:0000313|EMBL:CAB54395.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-8 [Caenorhabditis elegans] ZK896.4 gene20293 258 214 217 121 67 65 12.618775 10.12871 10.17143 5.834238 3.182262 3.118283 1.8402960673718e-06 -1.45553205688807 down -- -- -- -- -- -- -- CUB-like domain Protein ZK896.4 {ECO:0000313|EMBL:CAB05319.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein ZK896.4 [Caenorhabditis elegans] ugt-51 gene34471 262 216 249 595 625 971 8.66015700016628 6.21228271080702 8.57474441001542 17.2052494 15.2838050000059 23.71264 0.000442824667598084 1.58537830344013 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-51 {ECO:0000313|EMBL:CCD83358.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein UGT-51 [Caenorhabditis elegans] W01B6.2 gene19210 124 149 188 81 68 71 6.76269 8.06669 10.3921 4.59235 3.79017 3.96506 0.0018767213905955 -1.07457191025996 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein W01B6.2 {ECO:0000313|EMBL:CAA92625.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein W01B6.2 [Caenorhabditis elegans] nas-22 gene37046 25 39 50 16 16 10 1.58265949773 2.4610237829 3.135307 0.998661 1.022863 0.66768648724 0.00852760568583568 -1.44808433019911 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; -- -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis briggsae PE=3 SV=2 S Function unknown Protein NAS-22 [Caenorhabditis elegans] ZK1025.3 gene3158 165 228 99 3 2 1 9.25135 13.213549 5.823307 0.23797500787851 0.168936750047 0.120238725042 1.18167607864747e-10 -6.36884265279132 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein ZK1025.3 {ECO:0000313|EMBL:CAA18370.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein ZK1025.3 [Caenorhabditis elegans] Y60C6A.1 gene34331 16 21 15 36 49 52 2.44486 3.16102 2.33903 5.40018 7.23441 7.76635 0.00355165505832025 1.39120463196922 up -- -- -- -- -- -- -- CX module Protein Y60C6A.1 {ECO:0000313|EMBL:CCD65238.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y60C6A.1 [Caenorhabditis elegans] Y73F4A.1 gene18776 112 153 167 287 298 302 19.8325 25.0578 27.7887 50.4571 49.5428 52.5277 0.000494266239602384 1.03123557760802 up -- -- -- -- -- -- -- DOMON domain Putative uncharacterized protein {ECO:0000313|EMBL:EFP07937.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 R General function prediction only Protein Y73F4A.1 [Caenorhabditis elegans] F07C4.12 gene35427 80 55 61 221 258 495 3.71320961 2.5514626532504 2.840963263 10.133143 11.4251479 22.172611857 0.0076688992665172 2.3074181262333 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein F07C4.12, isoform b {ECO:0000313|EMBL:CCD64302.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein F07C4.12, isoform b [Caenorhabditis elegans] oac-41 gene35937 280 233 107 2 47 11 11.2064 9.31459 4.20452 0.113603 1.89648 0.471646 0.000209891082356598 -3.37493100026233 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-41 {ECO:0000313|EMBL:CCD65674.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein OAC-41 [Caenorhabditis elegans] AC7.3 gene15003 36 46 33 11 14 11 4.1833 5.3127 3.94163 1.35801 1.74035 1.37177 0.000740380644293657 -1.68295722759059 down -- -- -- -- -- -- -- -- Protein AC7.3 {ECO:0000313|EMBL:CCD61153.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein AC7.3 [Caenorhabditis elegans] Y47D3B.3 gene12681 395 399 231 79 108 102 20.95237140241 21.47906 14.221245 4.04231100879926 6.786754 4.6382534711 5.11879210825064e-05 -1.83388271264669 down -- -- -- -- -- -- -- -- Protein Y47D3B.3 {ECO:0000313|EMBL:CAA21038.4} OS=Caenorhabditis elegans PE=4 SV=4 O Posttranslational modification, protein turnover, chaperones Protein Y47D3B.3 [Caenorhabditis elegans] W03D2.9 gene14205 153 123 70 29 29 37 33.8598 24.26174 16.71076 5.339055 7.28749 7.53191 0.00276383341264079 -1.87282599327753 down -- -- -- -- -- -- -- -- Protein W03D2.9 {ECO:0000313|EMBL:CCD66767.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein W03D2.9 [Caenorhabditis elegans] W01C9.2 gene7323 1640 1296 684 146 309 177 48.14282 37.80966 19.88185 4.212745779 8.841861 5.31514724 0.000740380644293657 -2.52575557314366 down -- -- -- -- -- -- -- -- Protein W01C9.2 {ECO:0000313|EMBL:CAA90270.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein W01C9.2 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_325 23 26 27 8 7 8 1.23619 1.29345 1.36027 0.44111 0.36769 0.440165 0.0025289751734808 -1.73170751405277 down -- -- -- -- -- -- -- -- Protein Y69A2AR.12 {ECO:0000313|EMBL:CCD74138.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only -- K08D9.6 gene33848 590 500 247 35 82 27 20.3231 17.0329 8.45664 1.21674 2.83315 0.933115 4.51692764049786e-05 -3.22323283758597 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein K08D9.6 {ECO:0000313|EMBL:CCD72797.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein K08D9.6 [Caenorhabditis elegans] fut-2 gene34991 239 212 116 60 58 46 16.9291245 14.96481291377 8.02299713505 4.278627921132 4.1834190740291 3.175579239 0.00163103529946489 -1.7989782244241 down -- -- Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; -- -- -- -- Glycosyl transferase family 11 Protein FUT-2 {ECO:0000313|EMBL:CCD68841.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein FUT-2 [Caenorhabditis elegans] F47D12.3 gene11088 25 27 10 48 54 57 9.42688 9.21834 3.56339 18.5932 18.3918 20.8376 0.0030394584472563 1.35052072272353 up -- -- Biological Process: protein homooligomerization (GO:0051260);; -- -- [R] General function prediction only BTB/POZ domain Protein CBG17460 {ECO:0000313|EMBL:CAP35126.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein F47D12.3 [Caenorhabditis elegans] ZK484.7 gene1400 64 64 77 29 25 21 3.86641 3.8137 4.7087 1.80086 1.50548 1.28045 0.000513454686862552 -1.45883752365092 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain Protein ZK484.7 {ECO:0000313|EMBL:CCD65804.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK484.7 [Caenorhabditis elegans] C17H12.8 gene17816 4569 4512 4097 2248 1649 1771 279.6061 269.842 242.6577 134.1288 98.5926 106.9905 2.76619258590668e-10 -1.22586184361332 down -- -- -- -- -- -- -- CUB-like domain Protein C17H12.8 {ECO:0000313|EMBL:CCD64997.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C17H12.8 [Caenorhabditis elegans] F10D11.5 gene2128 47 58 76 26 21 23 1.6199 1.99428 2.59517 0.91741 0.73084 0.796556 0.0016142448182236 -1.37777432671051 down -- -- -- -- -- -- -- -- Protein F10D11.5 {ECO:0000313|EMBL:CAB02918.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F10D11.5 [Caenorhabditis elegans] bca-1 gene42778 763 789 698 1351 1621 1913 61.5744769301 56.5060164783 51.7441959022 84.1766402638 95.5766909199 118.8522856854 3.2768220604245e-06 1.11186333338488 up [P] Inorganic ion transport and metabolism Molecular Function: carbonate dehydratase activity (GO:0004089);; Molecular Function: zinc ion binding (GO:0008270);; -- -- [P] Inorganic ion transport and metabolism Carbonic anhydrase CBN-BCA-1 protein {ECO:0000313|EMBL:EGT43056.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 K Transcription Protein BCA-1 [Caenorhabditis elegans] asp-17 gene40149 36 31 33 173 158 326 1.912259 1.4467411192 1.5618045 8.77921 7.50729 15.62547 0.00086608601262572 2.71004234877289 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-17 {ECO:0000313|EMBL:CAD31821.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport hypothetical protein Y39B6B.j [imported] - Caenorhabditis elegans C02F5.12 gene11694 632 520 814 242 252 247 32.939786 25.696701007 41.54833 13.142838 13.431217081 12.8759415 9.58615550134852e-06 -1.41466253809814 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP09209.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein C02F5.12 [Caenorhabditis elegans] C44B7.7 gene6735 147 165 119 313 335 327 25.2697 26.6345 19.8498 55.173 54.9411 55.8744 4.06909315230913e-05 1.17006886657514 up -- -- -- K00682|2.17365e-139|cel:CELE_C44B7.7|C44B7.7; Protein C44B7.7; K00682 gamma-glutamylcyclotransferase [EC:2.3.2.4] (A) Glutathione metabolism (ko00480) [S] Function unknown AIG2-like family Protein C44B7.7 {ECO:0000313|EMBL:CCD61561.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein C44B7.7 [Caenorhabditis elegans] nlp-76 gene45106 6190 4699 7356 934 783 2483 314.378980000002 245.8181805 370.46787897 72.4803079525 71.7837615605 159.993441901098 6.36991260234045e-07 -2.12336424443693 down -- -- -- -- -- -- -- -- Protein C02B4.4 {ECO:0000313|EMBL:CAN86589.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein C02B4.4 [Caenorhabditis elegans] npax-2 gene41287 71 83 63 30 27 38 7.74944 8.42805 6.49868 3.25852 2.81468 4.12212 0.00427987315189322 -1.19878218953933 down -- -- Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; -- -- [K] Transcription 'Paired box' domain;; Homeodomain-like domain Protein NPAX-2 {ECO:0000313|EMBL:CCD68824.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein NPAX-2 [Caenorhabditis elegans] dos-1 gene12004 59 59 58 223 246 202 6.99917 7.01112 6.47459 24.78557 26.54281 23.43576 3.74328193890993e-10 1.9230522821319 up -- -- -- -- -- -- -- -- CRE-DOS-1 protein {ECO:0000313|EMBL:EFP09638.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein DOS-1 [Caenorhabditis elegans] comt-4 gene33442 13 7 8 53 67 61 1.7317 0.937211 1.05902 7.18546 8.59761 7.86229 2.8599916289943e-09 2.68461852436811 up [R] General function prediction only Molecular Function: O-methyltransferase activity (GO:0008171);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism O-methyltransferase;; Methyltransferase domain Protein COMT-4 {ECO:0000313|EMBL:CCD70634.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein COMT-4 [Caenorhabditis elegans] T21F4.1 gene42517 1797 1703 2022 657 678 829 79.6173 75.623 90.5352 29.30866 30.9338 36.71005 3.62830717686043e-11 -1.3581192934962 down [E] Amino acid transport and metabolism Molecular Function: metal ion binding (GO:0046872);; -- -- [E] Amino acid transport and metabolism Arginase family Protein T21F4.1, isoform b {ECO:0000313|EMBL:CCD69509.1} OS=Caenorhabditis elegans PE=4 SV=1 E Amino acid transport and metabolism Protein T21F4.1, isoform b [Caenorhabditis elegans] cld-9 gene38008 1023 1289 964 366 253 269 47.6023691522 59.110339976 43.3310409 16.7241864675 11.5601565282 12.36143806 1.69353105757672e-14 -1.89210270845379 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.8, isoform a {ECO:0000313|EMBL:CAB04278.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F35E12.8, isoform a [Caenorhabditis elegans] col-114 gene18098 4731 3677 1817 137 546 215 253.6 190.954 95.4482 7.41474 28.4213 11.3255 6.60192438642993e-05 -3.51627424897094 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-114 {ECO:0000313|EMBL:CCD63361.1} OS=Caenorhabditis elegans PE=4 SV=2 Z Cytoskeleton Protein COL-114 [Caenorhabditis elegans] pck-2 gene1973 16946 13449 15083 38993 40366 48336 508.671054762742 408.817050718826 457.414071899092 1201.2800864663 1237.3389553641 1471.21005929587 2.21627096884106e-12 1.48236048484217 up [C] Energy production and conversion Molecular Function: phosphoenolpyruvate carboxykinase activity (GO:0004611);; Biological Process: gluconeogenesis (GO:0006094);; K01596|0|cbr:CBG08279|Hypothetical protein CBG08279; K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] (A) Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; FoxO signaling pathway (ko04068) [C] Energy production and conversion Phosphoenolpyruvate carboxykinase Protein PCK-2, isoform a {ECO:0000313|EMBL:CAB05600.1} OS=Caenorhabditis elegans PE=1 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein PCK-2, isoform a [Caenorhabditis elegans] ech-7 gene4030 403 474 587 2369 2276 2611 37.1568 41.9287 53.3101 220.269 204.966 235.852 2.63170536202287e-30 2.30264036076684 up [I] Lipid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; -- -- [I] Lipid transport and metabolism Enoyl-CoA hydratase/isomerase family Protein ECH-7 {ECO:0000313|EMBL:CAC48118.1} OS=Caenorhabditis elegans PE=3 SV=1 P Inorganic ion transport and metabolism Protein ECH-7 [Caenorhabditis elegans] col-88 gene9389 384 462 696 197 122 173 23.0306 26.7456 40.6416 12.0153 7.15831 10.1845 0.00108069388706832 -1.65533808404776 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-88 {ECO:0000313|EMBL:CCD71750.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-88 [Caenorhabditis elegans] str-7 gene39023 5 7 3 34 54 38 0.526014 0.85340608 0.443092797827 3.306758 4.978265381 3.279993436 4.48851531332826e-09 3.06291753690857 up -- -- -- K08473|0|cel:CELE_F22B8.5|str-7; Protein STR-7; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri Protein STR-7 {ECO:0000313|EMBL:CAB05496.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein STR-7 [Caenorhabditis elegans] tatn-1 gene45849 13410 13181 10640 3386 3498 3135 447.909 430.538 350.8551 112.0441 112.6685 101.6473 5.27881271183003e-23 -1.90181342341958 down [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K00815|0|cel:CELE_F42D1.2|tatn-1; Protein TATN-1; K00815 tyrosine aminotransferase [EC:2.6.1.5] (A) Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Cysteine and methionine metabolism (ko00270);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Aminotransferase class I and II;; DegT/DnrJ/EryC1/StrS aminotransferase family;; Cys/Met metabolism PLP-dependent enzyme Protein TATN-1 {ECO:0000313|EMBL:CAB03090.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein TATN-1 [Caenorhabditis elegans] ins-5 gene6347 42 53 37 100 95 117 14.82219 11.597 5.35271138973 15.00392489 13.4228241235 19.42456 0.00109636113566782 1.23372402590839 up -- -- Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; -- -- -- -- Nematode insulin-related peptide beta type Protein DAF-28 {ECO:0000313|EMBL:CAB61047.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein INS-5 [Caenorhabditis elegans] fbxa-156 gene39776 42 31 33 67 67 98 2.8862 2.18837 2.28558 4.68847 4.6267 6.89045 0.00700601120150557 1.12318839125633 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain Protein FBXA-156 {ECO:0000313|EMBL:CAB07161.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein FBXA-156 [Caenorhabditis elegans] C14C6.3 gene33031 73 85 93 9 7 4 4.62711 4.681405 5.56937 0.589398 0.483955 0.36330076398 2.30881183150033e-16 -3.65898012158997 down -- -- Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; -- -- -- -- Glycosyl transferase family 11 Protein C14C6.3 {ECO:0000313|EMBL:CCD64460.1} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C14C6.3 [Caenorhabditis elegans] T21G5.1 gene1690 47 72 78 31 19 35 1.450980544872 2.352761 2.491985 0.98039941873 0.6142882286 1.13319149441 0.00467907751096942 -1.21934404295948 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein tyrosine kinase;; Protein kinase domain;; SH2 domain Protein T21G5.1 {ECO:0000313|EMBL:CCD67589.1} OS=Caenorhabditis elegans PE=4 SV=3 A RNA processing and modification Protein T21G5.1 [Caenorhabditis elegans] F20C5.7 gene18666 81 74 30 0 3 3 6.08066 5.61488 2.29433 0.0703082 0.277937 0.293082 5.63260483792682e-06 -4.94996669062742 down -- -- -- -- -- [MW] Cell wall/membrane/envelope biogenesis;; Extracellular structures -- Protein F20C5.7 {ECO:0000313|EMBL:CAD89736.1} OS=Caenorhabditis elegans PE=4 SV=1 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein F20C5.7 [Caenorhabditis elegans] F23D12.3 gene45710 80 76 86 154 174 213 12.7753 11.2178 12.7685 24.8008 25.9354 33.7266 0.000469075086359849 1.15422258680587 up -- -- -- -- -- -- -- -- Protein F23D12.3 {ECO:0000313|EMBL:CAA94915.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F23D12.3 [Caenorhabditis elegans] C17F4.3 gene5334 22 33 46 90 120 178 2.45905 3.5234 5.031 9.97316 12.7585 19.1089 0.00171502355283293 1.93745629856299 up -- -- -- -- -- -- -- -- Protein C17F4.3 {ECO:0000313|EMBL:CCD64908.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17F4.3 [Caenorhabditis elegans] F11D11.3 gene40070 51 76 69 26 22 18 3.088347 4.676701 4.052857 1.5512955949 1.2978095757 1.0584630685 0.000198162558192992 -1.5784652383179 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein F11D11.3 {ECO:0000313|EMBL:CAB04096.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein F11D11.3 [Caenorhabditis elegans] T07E3.4 gene11265 1026 814 1105 2804 2912 3311 51.49370937202 41.02150385659 56.41210599232 145.60180371758 148.93450410238 169.81050460201 1.68181122654635e-16 1.6090902892935 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- F-box domain Protein T07E3.4, isoform a {ECO:0000313|EMBL:CCD72023.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T07E3.4, isoform a [Caenorhabditis elegans] Y22D7AR.7 gene9808 74 71 79 23 17 6 1.2756107556 1.36049700000038 1.3872626500301 0.4739632595 0.49583725272 0.1378964 2.9313360779729e-08 -2.29450229692566 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- Protein-tyrosine phosphatase Protein Y22D7AR.7 {ECO:0000313|EMBL:CCD73762.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein Y22D7AR.7 [Caenorhabditis elegans] clec-232 gene38962 61 61 81 12 7 4 4.28499 4.01276 5.49936 0.840889 0.55738600069221 0.311202 3.52416750274146e-12 -3.15215476872844 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms -- Protein CLEC-232 {ECO:0000313|EMBL:CAB04330.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-232 [Caenorhabditis elegans] F07C4.6 gene35414 174 182 103 23 37 46 29.0036 29.1256 16.4759 3.99282 5.94717 7.63895 1.63588357664767e-05 -2.12061362912166 down -- -- -- -- -- -- -- ShK domain-like Protein F07C4.6 {ECO:0000313|EMBL:CCD64295.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F07C4.6 [Caenorhabditis elegans] slc-17.3 gene11562 88 113 68 228 190 206 3.791477467 5.007414037 3.1022811185 9.77732320486 8.23969370112383 8.811325 0.000139361543772738 1.20563005657328 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Putative uncharacterized protein {ECO:0000313|EMBL:EGT56567.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 C Energy production and conversion Protein C02C2.4 [Caenorhabditis elegans] cdr-4 gene37497 3179 3714 3100 1973 1478 1181 280.781 323.996 265.793 176.0148 129.7143 108.1131 1.59642923884858e-08 -1.1184751765298 down -- -- Molecular Function: protein binding (GO:0005515);; Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: protein targeting to mitochondrion (GO:0006626);; -- -- [T] Signal transduction mechanisms Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein CDR-4 {ECO:0000313|EMBL:CAA99876.1} OS=Caenorhabditis elegans PE=2 SV=1 P Inorganic ion transport and metabolism Protein CDR-4 [Caenorhabditis elegans] clec-12 gene3510 315 257 161 65 95 89 15.98631 12.19154 7.47393 3.263809 4.444454 4.176053 0.00251357747894776 -1.56514504638632 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms CUB domain;; Lectin C-type domain Protein CLEC-12 {ECO:0000313|EMBL:CAB04882.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-12 [Caenorhabditis elegans] F23A7.4 gene46326 77 80 78 27 27 19 1342.15 1512.03 1588.43 784.655 524.625 470.755 2.45310260455329e-05 -1.69504650729104 down -- -- -- -- -- -- -- -- Protein F23A7.4 {ECO:0000313|EMBL:CAB02978.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein F23A7.4 [Caenorhabditis elegans] F53F4.7 gene37961 251 194 95 21 40 38 17.5652 13.1653 6.50573 1.53432 2.7379 2.73153 0.00313203230069011 -2.4545434855837 down -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein F53F4.7 {ECO:0000313|EMBL:CAB01207.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F53F4.7 [Caenorhabditis elegans] F39G3.2 gene34318 82 95 97 41 25 28 3.68726 4.2361 4.30581 1.93223 1.1126 1.24961 5.75744295272513e-05 -1.55222707971388 down -- -- -- -- -- -- -- Glycosyltransferase family 92 Protein F39G3.2 {ECO:0000313|EMBL:CCD65241.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein F39G3.2 [Caenorhabditis elegans] C18E9.8 gene7490 116 113 134 39 62 70 4.1184 4.09242 4.81796 1.45756 2.26001 2.56105 0.00289010950125402 -1.09140212377827 down -- -- -- -- -- -- -- -- Protein C18E9.8 {ECO:0000313|EMBL:CAA93857.1} OS=Caenorhabditis elegans PE=1 SV=1 T Signal transduction mechanisms Protein C18E9.8 [Caenorhabditis elegans] Y51H7C.13 gene4674 1220 1472 1608 768 590 478 43.09954416 45.4695777800003 49.6134142 23.681628 17.89646613328 14.789586157528 1.85237845346027e-08 -1.23633192388683 down -- -- -- -- -- -- -- -- Protein Y51H7C.13 {ECO:0000313|EMBL:CCD71799.1} OS=Caenorhabditis elegans PE=4 SV=2 A RNA processing and modification Protein Y51H7C.13 [Caenorhabditis elegans] C49G7.10 gene34133 1167 1217 1273 458 394 345 90.8882354377 90.189840748 95.6939477158 35.7980468429 29.7518297156 26.3883433238 8.12241165851619e-14 -1.61948848660473 down -- -- -- -- -- -- -- -- Protein C49G7.10 {ECO:0000313|EMBL:CCD67695.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C49G7.10 [Caenorhabditis elegans] Y51B9A.8 gene7629 58 67 74 15 12 3 15.5206 16.3884 18.4876 4.13377 3.02097 1.01411 5.0506511299291e-10 -2.74030186815906 down -- -- -- -- -- -- -- CC domain;; ShK domain-like Protein Y51B9A.8 {ECO:0000313|EMBL:CAA19536.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y51B9A.8 [Caenorhabditis elegans] cdr-1 gene38933 217 301 184 80 98 19 24.1938 32.5466 20.0749 9.11584 10.8944 2.16426 0.000261421970127095 -1.84323466412113 down -- -- -- -- -- [T] Signal transduction mechanisms Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain Protein CDR-1 {ECO:0000313|EMBL:CAB04302.1} OS=Caenorhabditis elegans PE=2 SV=1 R General function prediction only Protein CDR-1 [Caenorhabditis elegans] snf-7 gene13018 35 46 30 16 14 14 1.12749 1.49655 0.997379 0.539036 0.480732 0.470164 0.00876922155056114 -1.34318431800096 down -- -- Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [T] Signal transduction mechanisms Sodium:neurotransmitter symporter family Transporter {ECO:0000256|RuleBase:RU003732} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein SNF-7 [Caenorhabditis elegans] col-90 gene11590 2056 2006 1646 5853 5226 4816 159.4782 157.3833 127.6823 459.217 415.311 382.752 1.60575396906966e-14 1.46902122287218 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-COL-90 {ECO:0000313|EMBL:CAP31295.1} OS=Caenorhabditis briggsae PE=4 SV=1 F Nucleotide transport and metabolism Protein COL-90 [Caenorhabditis elegans] C26G2.2 gene45800 269 281 384 151 142 118 4.2512441777703 4.71650416400003 7.02210202765402 1.92105159651551 2.17412303293 1.70045967400001 3.30694712270801e-05 -1.19185784606525 down -- -- -- -- -- -- -- -- Protein C26G2.2 {ECO:0000313|EMBL:CAB63433.3} OS=Caenorhabditis elegans PE=4 SV=3 T Signal transduction mechanisms Protein C26G2.2 [Caenorhabditis elegans] K08D8.3 gene20304 168 181 96 670 663 615 6.43608 6.93175 3.707251 26.20948 26.56405 24.27853 3.71482251860632e-18 2.12156443225547 up -- -- -- -- -- -- -- CUB-like domain Protein K08D8.3 {ECO:0000313|EMBL:CAA97434.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein K08D8.3 [Caenorhabditis elegans] mce-1 gene1899 771 649 734 1863 1990 2023 149.6492 117.4116 137.9382 369.061 370.522 392.4 1.57212198473869e-12 1.44049991316492 up [E] Amino acid transport and metabolism -- K05606|4.60372e-114|cel:CELE_D2030.5|mce-1; Protein MCE-1; K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] (A) Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200) [G] Carbohydrate transport and metabolism Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain Protein MCE-1 {ECO:0000313|EMBL:CAA98118.1} OS=Caenorhabditis elegans PE=2 SV=1 G Carbohydrate transport and metabolism Protein MCE-1 [Caenorhabditis elegans] B0554.1 gene32989 90 112 40 0 10 0 2576.86 3464.64 1275.99 0 316.278 0 1.70324989071908e-05 -4.60276693156745 down -- -- -- -- -- -- -- -- Protein B0554.1 {ECO:0000313|EMBL:CCD62227.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein B0554.1 [Caenorhabditis elegans] F14H12.3 gene42073 216 228 274 614 570 666 16.75558 16.87052 20.84963 46.55631 41.2331 49.60752 2.89873047702951e-08 1.35854625756793 up -- -- -- -- -- -- -- Thrombospondin type 1 domain Protein F14H12.3 {ECO:0000313|EMBL:CCD65401.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein F14H12.3 [Caenorhabditis elegans] clec-3 gene5236 4265 4135 2148 305 272 20 198.3367 182.2815 97.9465 13.52292 11.72916 0.899395 1.18734659940205e-09 -4.15560109674093 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-3 {ECO:0000313|EMBL:CCD62000.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein CLEC-3 [Caenorhabditis elegans] msp-38 gene19247 71 115 112 32 56 47 35.2085 51.1766 52.6619 17.0981 26.2737 23.3015 0.00417308089210633 -1.14775735698839 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein MSP-38 [Caenorhabditis elegans] T07G12.3 gene19386 53 67 63 21 18 14 1.832831 2.3400103307 2.201364 0.765652 0.64949717643 0.51335 3.24043014601245e-05 -1.79620189045548 down -- -- -- -- -- -- -- Protein of unknown function (DUF229) Protein T07G12.3 {ECO:0000313|EMBL:CAB05275.2} OS=Caenorhabditis elegans PE=4 SV=2 F Nucleotide transport and metabolism Protein T07G12.3 [Caenorhabditis elegans] cyp-13A4 gene7785 484 1064 827 21 19 0 18.56285161 41.005047482 31.902613 0.8591091 0.757055578 0.03846635 1.11112236619065e-12 -5.90286743861972 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.1|cyp-13A4; Protein CYP-13A4; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Putative uncharacterized protein {ECO:0000313|EMBL:EGT38206.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A4 [Caenorhabditis elegans] acer-1 gene6740 4332 3865 5542 22671 23724 27989 194.974 174.306 249.78 1041.71 1074.56 1265.62 5.38818209493198e-34 2.43027250495375 up [C] Energy production and conversion Molecular Function: catalytic activity (GO:0003824);; Biological Process: acetyl-CoA metabolic process (GO:0006084);; -- -- [C] Energy production and conversion Acetyl-CoA hydrolase/transferase C-terminal domain;; Acetyl-CoA hydrolase/transferase N-terminal domain Protein C44B7.10 {ECO:0000313|EMBL:CCD61564.1} OS=Caenorhabditis elegans PE=1 SV=3 T Signal transduction mechanisms Protein C44B7.10 [Caenorhabditis elegans] nas-33 gene42884 271 252 172 98 85 99 8.68617996 8.069399 5.57253591825706 3.060818603259 2.7562492722254 3.19612163311359 7.60762748655072e-05 -1.3096396111101 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; K08076|0|cel:CELE_K04E7.3|nas-33; Protein NAS-33; K08076 astacin [EC:3.4.24.21] (A) -- [O] Posttranslational modification, protein turnover, chaperones Astacin (Peptidase family M12A) Metalloendopeptidase {ECO:0000256|RuleBase:RU361183} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein NAS-33 [Caenorhabditis elegans] fat-2 gene20439 9437 9317 10553 17888 20504 27559 617.29604591 599.531349576 679.277134704 1181.5360570923 1328.624157156 1797.9830957403 0.000388843138161324 1.16412836611973 up [I] Lipid transport and metabolism Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (GO:0016717);; Biological Process: oxidation-reduction process (GO:0055114);; K10257|0|cel:CELE_W02A2.1|fat-2; Protein FAT-2; K10257 omega-3 fatty acid desaturase (delta-15 desaturase) [EC:1.14.19.-] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) -- -- Fatty acid desaturase;; Domain of unknown function (DUF3474) Putative uncharacterized protein {ECO:0000313|EMBL:EGT37131.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein FAT-2 [Caenorhabditis elegans] F59E11.2 gene35928 107 100 73 174 199 247 8.03018 7.61095 5.57944 13.3364 15.0039 18.6692 0.000354720112257854 1.13977677000612 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [R] General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase Protein F59E11.2 {ECO:0000313|EMBL:CCD72133.1} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein F59E11.2 [Caenorhabditis elegans] pqn-97 gene33057 27 56 24 114 118 115 8.04538 14.9624 6.56466 33.4818 32.0457 33.1595 2.89685516572677e-06 1.68977854205954 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein PQN-97 {ECO:0000313|EMBL:CCD71528.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein PQN-97 [Caenorhabditis elegans] cyp-37A1 gene9085 584 556 465 1738 2298 3842 21.3077166713079 19.8009846047 16.942250027 64.6472728074 82.885234 139.092063 0.002472201340219 2.28971327797477 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17959|0|cel:CELE_F01D5.9|cyp-37A1; Protein CYP-37A1; K17959 cytochrome P450, family 37 (A) -- [QI] Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism Cytochrome P450 Protein CYP-37A1 {ECO:0000313|EMBL:CAB04044.2} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein CYP-37A1 [Caenorhabditis elegans] Y11D7A.3 gene18847 558 726 873 1432 1584 1697 46.523101 55.9430023467834 82.343637 103.44705420891 109.460211 113.45316 1.35795663476109e-07 1.12141421753454 up -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [S] Function unknown Ion channel regulatory protein UNC-93;; Major Facilitator Superfamily Protein Y11D7A.3, isoform a {ECO:0000313|EMBL:CAA21581.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y11D7A.3, isoform a [Caenorhabditis elegans] col-72 gene5464 2392 2271 772 79 280 158 157.7465 151.0316 50.3002 5.83712 18.42478 12.04612 0.000968614797812836 -3.40078267387357 down -- -- -- -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies) Protein COL-72, isoform b {ECO:0000313|EMBL:CCD73660.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-72, isoform b [Caenorhabditis elegans] dex-1 gene10836 3737 3009 2053 1018 1141 930 45.729191007 36.78418979729 25.068274848 12.0010900000496 13.50548091562 11.14414725 0.000665288877549085 -1.5188029302691 down -- -- Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell-matrix adhesion (GO:0007160);; -- -- [W] Extracellular structures Nidogen-like;; EGF domain;; Calcium-binding EGF domain;; EGF-like domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT39872.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein DEX-1, isoform c [Caenorhabditis elegans] K01D12.10 gene37496 444 350 145 13 49 26 54.9823 42.29 18.057 1.71078 6.06227 3.26302 0.000777676947590439 -3.42238910026435 down -- -- -- -- -- -- -- -- Protein K01D12.10 {ECO:0000313|EMBL:CAA99869.2} OS=Caenorhabditis elegans PE=4 SV=2 P Inorganic ion transport and metabolism Protein K01D12.10 [Caenorhabditis elegans] dhs-19 gene37058 1023 954 887 1619 1845 2713 59.5873 53.17934 48.16457 91.2128 103.5868 158.3378 0.0087794334123912 1.10265212744106 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- K15734|0|cel:CELE_T11F9.11|dhs-19; Protein DHS-19; K15734 all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] (A) Retinol metabolism (ko00830) [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain Protein DHS-19 {ECO:0000313|EMBL:CAA98524.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein DHS-19 [Caenorhabditis elegans] hpx-2 gene38047 423 287 138 4 32 3 11.6663 7.85264 3.81327 0.132005 0.899858 0.107478 8.74302217397846e-05 -4.45001145658026 down -- -- -- -- -- [R] General function prediction only Animal haem peroxidase Protein F09F3.5 {ECO:0000313|EMBL:CAB02910.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein F09F3.5 [Caenorhabditis elegans] C04G6.2 gene5953 86 111 112 2 6 6 15.55872 20.13862 19.45799 0.5379592 0.776427 0.948949 9.28601575307945e-23 -4.46810312488417 down -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF282 Protein C04G6.2 {ECO:0000313|EMBL:CCD63060.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C04G6.2 [Caenorhabditis elegans] bah-1 gene3159 32 47 31 0 0 0 1.436864 1.929547 1.44582533214 0.04356030587 0 0 3.54144216213417e-17 -Inf down -- -- -- -- -- -- -- Glycosyltransferase family 92 Protein BAH-1 {ECO:0000313|EMBL:CAA18365.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein BAH-1 [Caenorhabditis elegans] Y53F4B.39 gene9333 886 906 927 2083 1879 1861 46.5190202788 44.0094037773282 47.476011124134 110.938907000441 99.2086093469419 93.410198141774 1.45714219553896e-07 1.09086567550889 up [R] General function prediction only -- -- -- [R] General function prediction only Metallo-beta-lactamase superfamily;; Beta-lactamase superfamily domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT40884.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein Y53F4B.39, isoform b [Caenorhabditis elegans] C13G3.1 gene36767 151 130 117 53 59 81 65.819 51.0827 46.2959 23.9058 24.1322 35.2049 0.00351195888352897 -1.05085902312492 down -- -- -- -- -- -- -- -- Protein C13G3.1 {ECO:0000313|EMBL:CAA98421.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C13G3.1 [Caenorhabditis elegans] F44B9.9 gene11618 23 42 28 83 92 99 1.307785273 1.56409268 1.6417313217 3.31957620017063 6.1829341 1.589227160719 5.91005115197116e-05 1.55223621654464 up [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; -- -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 D Cell cycle control, cell division, chromosome partitioning Protein F44B9.9 [Caenorhabditis elegans] F13E9.14 gene19516 28 16 7 94 73 87 3.51937 1.99208 0.921116 11.6933 8.82721 10.5695 7.7364601891553e-09 2.30619088748738 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein F13E9.14 {ECO:0000313|EMBL:CAM06587.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F13E9.14 [Caenorhabditis elegans] acdh-1 gene1555 29 21 18 2740 4438 5949 1.5521626318 1.179086 0.96613925847 144.33936 230.90598 311.590889 1.94098574977407e-17 7.58676023893546 up [I] Lipid transport and metabolism Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; K09478|0|cbr:CBG12644|Cbr-acdh-1; C. briggsae CBR-ACDH-1 protein; K09478 short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12] (A) Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, middle domain Protein ACDH-1, isoform a {ECO:0000313|EMBL:CCD68091.1} OS=Caenorhabditis elegans PE=3 SV=1 P Inorganic ion transport and metabolism Protein ACDH-1, isoform a [Caenorhabditis elegans] asp-2 gene36021 6385 6861 5397 13059 11980 12948 301.7765 320.5063 251.7575 614.068 564.755 608.958 4.54206625419745e-07 1.01900814602729 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal;; A1 Propeptide Protein ASP-2, isoform a {ECO:0000313|EMBL:CCD65451.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only hypothetical protein T18H9.2 - Caenorhabditis elegans C13A2.12 gene35256 15037 13599 4375 614 1661 1166 1445.78 1256.94 407.993 60.3068 156.653 113.891 0.00269651543628271 -3.26908271380286 down -- -- -- -- -- -- -- -- Protein C13A2.12 {ECO:0000313|EMBL:CCD63104.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C13A2.12 [Caenorhabditis elegans] grl-17 gene37935 4464 3341 1677 121 479 169 194.127004 144.24456837 73.5972700033033 5.587397 20.4460900000003 7.03928439000484 7.03610492043818e-05 -3.63138487221979 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-17 {ECO:0000313|EMBL:CAB01137.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein GRL-17 [Caenorhabditis elegans] sru-22 gene38961 204 272 293 30 21 17 6.921182 7.905606 7.964455 1.33355340310341 0.9020442 1.00268671 3.213163643003e-25 -3.5081671265252 down -- -- Molecular Function: transmembrane signaling receptor activity (GO:0004888);; Biological Process: sensory perception of chemical stimulus (GO:0007606);; Cellular Component: membrane (GO:0016020);; -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Sru;; Srg family chemoreceptor Protein SRU-22 {ECO:0000313|EMBL:CAB04335.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein SRU-22 [Caenorhabditis elegans] wrt-7 gene38661 204 214 72 3 12 3 9.08685 9.32278 3.15702 0.170599 0.524568 0.171334 1.7369502444786e-05 -4.77422445979692 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; -- -- [T] Signal transduction mechanisms Hint module Protein WRT-7 {ECO:0000313|EMBL:CAB03509.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein WRT-7 [Caenorhabditis elegans] F35E12.10 gene38007 1121 1234 918 461 453 383 44.702183277 45.745369751 35.57336257 17.70833274 17.425448575 14.66399269 1.21488963179448e-09 -1.34374250287836 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.10 {ECO:0000313|EMBL:CAB04277.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.10 [Caenorhabditis elegans] oac-14 gene44249 303 341 451 3348 3841 5471 9.6619983203 10.78025223 14.1237436164 106.8747288265 122.8495217757 174.6170135299 1.40802419948519e-12 3.52591993831524 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-14 {ECO:0000313|EMBL:CAA90058.1} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein OAC-14 [Caenorhabditis elegans] Y49E10.16 gene12918 685 697 574 1088 1241 1737 39.2748700010688 39.1169100004086 34.3464000000002 63.387000000458 70.6357 101.422400008001 0.00455249626435311 1.04930101384981 up -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein Y49E10.16, isoform a {ECO:0000313|EMBL:CAB11552.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein Y49E10.16, isoform a [Caenorhabditis elegans] F53F1.6 gene37892 94 78 77 269 348 627 5.9466541401 5.06019400026653 5.090038 16.755115 22.3110817 39.1749959 0.00651926639510429 2.31539448365064 up -- -- -- -- -- -- -- -- Protein F53F1.6, isoform b {ECO:0000313|EMBL:CCM09389.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F53F1.6, isoform b [Caenorhabditis elegans] C49G7.12 gene34132 879 1122 1063 230 217 97 80.78370870755 96.71070909224 91.3164237905 20.8656185828 18.86480783754 8.8454935882 5.71269819396279e-28 -2.50294710913819 down -- -- -- -- -- -- -- -- Protein C49G7.12 {ECO:0000313|EMBL:CCD67693.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C49G7.12 [Caenorhabditis elegans] ZK228.3 gene39974 526 673 501 235 203 170 35.190931 44.4640125 34.2357773215 15.973107 13.9110005018 11.3506936 1.90399249790962e-09 -1.4919521930807 down -- -- -- -- -- -- -- -- Protein ZK228.3 {ECO:0000313|EMBL:CAB04995.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein ZK228.3 [Caenorhabditis elegans] F11E6.6 gene32878 1858 2507 2195 5223 4715 4429 104.10082 135.059819 124.76475 294.967709 261.883532 243.706728 8.64775855846599e-09 1.12322968475877 up -- -- -- -- -- [S] Function unknown Frag1/DRAM/Sfk1 family Protein F11E6.6 {ECO:0000313|EMBL:CAB62801.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F11E6.6 [Caenorhabditis elegans] F28C10.3 gene40855 319 262 321 106 100 73 12.3010363198914 8.894818411 11.8591233 3.51639726606 3.5241257 2.38855160164063 2.44756667815692e-09 -1.70136588982538 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [RT] General function prediction only;; Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein F28C10.3 {ECO:0000313|EMBL:CCD61756.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein F28C10.3 [Caenorhabditis elegans] K11G9.1 gene35022 348 385 433 62 64 77 12.8707 14.3789 16.1444 2.38747 2.39316 2.90311 6.42259334453993e-20 -2.52851893088701 down [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein K11G9.1 {ECO:0000313|EMBL:CCD72924.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein K11G9.1 [Caenorhabditis elegans] oac-56 gene22832 258 207 143 8 40 21 9.806815 7.811302 5.28565957 0.3254779171 1.54352 0.80903856051 1.23837335777131e-08 -3.1451098976789 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-56 {ECO:0000313|EMBL:CAB60446.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein OAC-56 [Caenorhabditis elegans] F31E8.5 gene6695 108 159 172 68 67 66 4.83145 7.21736 7.78578 3.09491 3.08565 3.04242 0.00109609029473672 -1.13385822316433 down -- -- -- -- -- -- -- -- Protein F31E8.5 {ECO:0000313|EMBL:CCD62856.1} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein F31E8.5 [Caenorhabditis elegans] rol-6 gene7397 2229 2285 1884 4664 4546 4938 94.9038 94.1774 78.11408 195.3557 187.7461 203.4541 5.53780054839972e-09 1.13726765048363 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-ROL-6 {ECO:0000313|EMBL:CAP23494.1} OS=Caenorhabditis briggsae PE=4 SV=1 W Extracellular structures Protein ROL-6 [Caenorhabditis elegans] F38A1.9 gene13515 42 67 51 108 158 129 2.220776158906 2.86189200000479 1.841077971 6.234044 7.357055 6.378837 0.000247240872609265 1.29736080442991 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms -- Protein F38A1.9 {ECO:0000313|EMBL:CCD63953.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F38A1.9 [Caenorhabditis elegans] F15H10.8 gene36482 255 234 156 77 102 71 18.0168 16.0527 10.6376 5.39964 7.04947 5.0887 0.000269042766395443 -1.37557563487235 down -- -- -- -- -- -- -- -- Protein F15H10.8 {ECO:0000313|EMBL:CAB60280.2} OS=Caenorhabditis elegans PE=4 SV=1 DO Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones Protein F15H10.8 [Caenorhabditis elegans] faah-6 gene12749 104 109 84 221 277 298 3.509597567 3.5798546 2.80260114 7.678522 9.407447 9.939354 1.62140947805474e-06 1.41543449249901 up [J] Translation, ribosomal structure and biogenesis -- -- -- [JIT] Translation, ribosomal structure and biogenesis;; Lipid transport and metabolism;; Signal transduction mechanisms Amidase Protein FAAH-6 {ECO:0000313|EMBL:CAB63353.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein FAAH-6 [Caenorhabditis elegans] chil-22 gene7668 253 286 201 482 470 561 12.1952234 13.77605 9.57228 23.450821807 22.78887682 27.593006507 9.16944610158586e-05 1.02436411240043 up [G] Carbohydrate transport and metabolism Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 18 Protein CHIL-22 {ECO:0000313|EMBL:CAA93870.2} OS=Caenorhabditis elegans PE=3 SV=2 G Carbohydrate transport and metabolism Protein R09D1.10 [Caenorhabditis elegans] T24A6.7 gene33961 42 44 72 4 12 8 6.02656 6.1267 10.0858 0.67639 1.67634 1.23711 7.49206222553433e-06 -2.72311078693207 down -- -- -- K09935|3.14317e-153|cel:CELE_T24A6.7|T24A6.7; Protein T24A6.7; K09935 hypothetical protein (A) -- -- -- Domain of unknown function (DUF1768) Protein T24A6.7 {ECO:0000313|EMBL:CCD63571.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein T24A6.7 [Caenorhabditis elegans] clec-51 gene18472 98 104 95 250 222 296 8.77680000045266 9.18568 8.98427 22.2250000000004 19.5537000000001 26.4492057 4.87289375356241e-06 1.36347943326514 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-51, isoform a {ECO:0000313|EMBL:CCD61388.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein CLEC-51 [Caenorhabditis elegans] dhs-21 gene37630 852 876 936 1562 1705 2180 88.10741 88.82913 95.71880406 158.2395812 173.36080519 224.84851079 2.41660917756833e-05 1.02551313253008 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- K03331|0|cel:CELE_R11D1.11|dhs-21; Protein DHS-21; K03331 L-xylulose reductase [EC:1.1.1.10] (A) Pentose and glucuronate interconversions (ko00040) [Q] Secondary metabolites biosynthesis, transport and catabolism short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; Polysaccharide biosynthesis protein CRE-DHS-21 protein {ECO:0000313|EMBL:EFP05398.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 R General function prediction only Protein DHS-21 [Caenorhabditis elegans] spch-1 gene19230 316 374 395 203 164 154 54.7852 61.9217 66.9264 35.978 27.9718 26.7006 0.000145188142988143 -1.06641721695086 down -- -- -- -- -- -- -- -- Protein C04G2.8 {ECO:0000313|EMBL:CAA94670.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein C04G2.8 [Caenorhabditis elegans] oac-51 gene14306 229 202 270 431 402 576 8.1491295389 7.198708679473 9.45793 15.587135382 14.3284003227 20.0175518009 0.000588996687066595 1.00074949778037 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-51, isoform a {ECO:0000313|EMBL:CCD71912.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein OAC-51 [Caenorhabditis elegans] Y68A4B.3 gene39529 42 39 60 1 0 1 5.55848 4.93119 7.62011 0.247894 0 0.25042112 6.68023882020035e-18 -6.14775620295648 down -- -- -- -- -- -- -- -- Protein Y68A4B.3 {ECO:0000313|EMBL:CAA19556.2} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein Y68A4B.3 [Caenorhabditis elegans] T24B8.5 gene7533 30 21 55 7 7 0 55.3849 34.159 93.2691 16.4732 12.4278 1.88543 0.00634793155935403 -2.93089535133809 down -- -- -- -- -- -- -- ShK domain-like Protein T24B8.5 {ECO:0000313|EMBL:CAA92755.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein T24B8.5 [Caenorhabditis elegans] F35E12.6 gene38004 5045 6704 5286 1571 1389 1175 299.82561 396.70992 299.79617 90.19584 74.013537 61.06382 1.08303088057226e-17 -2.05084232134632 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.6 {ECO:0000313|EMBL:CAB04273.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F35E12.6 [Caenorhabditis elegans] F36F12.1 gene33456 55 61 73 154 163 217 1.960850199635 2.1467418141 2.54383 5.48036471298 5.71893 7.6412632693 4.30289310937798e-06 1.49243693670295 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein F36F12.1 {ECO:0000313|EMBL:CCD69870.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F36F12.1 [Caenorhabditis elegans] Y46G5A.36 gene8784 35 47 24 5 13 8 23.6297 28.1991 15.01 4.16182 8.60697 5.95089 0.000849966076673612 -2.03373185366738 down -- -- -- -- -- -- -- -- Protein Y46G5A.36 {ECO:0000313|EMBL:CAE18013.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein Y46G5A.36 [Caenorhabditis elegans] gmd-2 gene3442 316 218 303 46 18 8 15.4997 10.2919 14.4573 2.29196 0.88971 0.418617 1.60138883322376e-20 -3.55205068974677 down [M] Cell wall/membrane/envelope biogenesis Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; K01711|0|cel:CELE_F56H6.5|gmd-2; Protein GMD-2; K01711 GDPmannose 4,6-dehydratase [EC:4.2.1.47] (A) Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520) [G] Carbohydrate transport and metabolism NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; Polysaccharide biosynthesis protein Putative uncharacterized protein {ECO:0000313|EMBL:EGT46220.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 R General function prediction only Protein GMD-2 [Caenorhabditis elegans] lsy-2 gene41262 7524 6130 3283 817 1571 942 273.754527832318 227.159427852116 109.28358203277 25.065057269315 41.8047886132 26.1098211427007 0.000713956965917727 -2.35445269504272 down [R] General function prediction only -- -- -- [R] General function prediction only Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger Protein LSY-2, isoform a {ECO:0000313|EMBL:CCD71575.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein LSY-2, isoform a [Caenorhabditis elegans] T01D3.6 gene37995 8623 11923 13562 4071 3296 3096 149.115796 204.689389 230.03432176404 70.0805263445 56.5338784437 53.166248 1.69732654260819e-07 -1.7125095537526 down -- -- Molecular Function: calcium ion binding (GO:0005509);; -- -- [WV] Extracellular structures;; Defense mechanisms Fibrinogen beta and gamma chains, C-terminal globular domain;; von Willebrand factor type D domain;; Trypsin Inhibitor like cysteine rich domain;; Calcium-binding EGF domain Protein T01D3.6, isoform a {ECO:0000313|EMBL:CAB03262.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein T01D3.6, isoform a [Caenorhabditis elegans] F58A6.5 gene5977 61 61 50 29 13 27 5.72824 5.63028 4.67496 2.77211 1.28818 2.51798 0.00289010950125402 -1.32642319561971 down -- -- -- -- -- -- -- Interactor of ZYG-11 Protein F58A6.5 {ECO:0000313|EMBL:CCD65836.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein F58A6.5 [Caenorhabditis elegans] C35B1.5 gene14210 2751 2799 2523 7082 6051 5926 469.4802 434.1447 417.9375 1245.547 937.747 955.256 2.09206733752507e-10 1.23102193468671 up -- -- Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; K17609|3.8915e-106|cel:CELE_C35B1.5|C35B1.5; Protein C35B1.5; K17609 nucleoredoxin [EC:1.8.1.8] (A) -- [R] General function prediction only Thioredoxin-like;; Thioredoxin;; Thioredoxin;; AhpC/TSA family;; Redoxin;; SCO1/SenC Protein C35B1.5 {ECO:0000313|EMBL:CCD66740.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C35B1.5 [Caenorhabditis elegans] alg-4 gene12275 456 628 635 272 229 325 8.5449372555 11.900519 12.002547 5.166313244 4.324358 6.083207 3.49454617873522e-05 -1.06393531656364 down -- -- Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; -- -- [J] Translation, ribosomal structure and biogenesis Piwi domain;; PAZ domain;; Domain of unknown function (DUF1785) Protein ALG-3, isoform b {ECO:0000313|EMBL:CAA92619.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein TAG-76, isoform a [Caenorhabditis elegans] C31H2.4 gene42343 54 73 85 253 237 185 3.18961 4.125368391 4.89646 14.74281 13.67269 10.59082 5.18867838637091e-08 1.66320911306395 up [ER] Amino acid transport and metabolism;; General function prediction only -- K00457|0|cel:CELE_C31H2.4|C31H2.4; Protein C31H2.4; K00457 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] (A) Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360) [E] Amino acid transport and metabolism Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT29946.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein C31H2.4 [Caenorhabditis elegans] pud-3 gene33541 285 358 543 80 14 38 61.5005 71.0787 110.23 17.5153 2.87624 8.03362 7.78936121925469e-07 -3.17778851369318 down -- -- -- -- -- -- -- -- Protein PUD-3, isoform a {ECO:0000313|EMBL:CCD69543.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein PUD-3, isoform a [Caenorhabditis elegans] ptr-13 gene8224 1159 1052 976 1912 2217 3161 29.4535455 21.424507528573 20.7021471354183 41.6390140973106 50.8594743 70.070611861 0.00306542705418096 1.18741306681737 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [R] General function prediction only Patched family;; Sterol-sensing domain of SREBP cleavage-activation;; Protein export membrane protein Protein PTR-13 {ECO:0000313|EMBL:CAA87375.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein PTR-13 [Caenorhabditis elegans] str-112 gene35213 44 22 30 83 104 135 3.95725 1.941291 2.554608 6.99906 8.322089 12.02884 4.32568363692068e-05 1.7391541380582 up -- -- -- K08473|0|cel:CELE_F10D2.4|str-112; Protein STR-112; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri Protein STR-112 {ECO:0000313|EMBL:CCD69118.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein STR-112 [Caenorhabditis elegans] F49C12.3 gene18868 7 9 1 95 112 97 0.531464 0.659667 0.130529 6.81526 7.94912 6.94805 8.15909828536101e-21 4.15139524615728 up -- -- -- -- -- -- -- Nucleotide-diphospho-sugar transferase Protein F49C12.3 {ECO:0000313|EMBL:CAA92508.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown F49C12.3 [Caenorhabditis elegans] aco-1 gene44649 3432 3590 3551 10240 9837 10056 71.5283 73.335 72.6162 213.204 201.025 205.868 7.00703825424076e-15 1.50343605820168 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; K01681|0|cel:CELE_ZK455.1|aco-1; Protein ACO-1; K01681 aconitate hydratase [EC:4.2.1.3] (A) Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [AJ] RNA processing and modification;; Translation, ribosomal structure and biogenesis Aconitase family (aconitate hydratase);; Aconitase C-terminal domain CBN-ACO-1 protein {ECO:0000313|EMBL:EGT30572.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein ACO-1 [Caenorhabditis elegans] ZC376.3 gene38174 179 181 120 439 410 605 5.34647 5.54059 3.59778 13.3861 12.4874 18.4967 3.67129200189072e-06 1.59166144485144 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein ZC376.3 {ECO:0000313|EMBL:CAB00887.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZC376.3 [Caenorhabditis elegans] K11H3.3 gene12259 1240 1355 1453 2913 2944 3253 60.273 67.6298 73.4707 141.5838 139.2888 156.3014 4.35918756411805e-09 1.16332449627552 up -- -- -- K15100|0|cel:CELE_K11H3.3|K11H3.3; Protein K11H3.3; K15100 solute carrier family 25 (mitochondrial citrate transporter), member 1 (A) -- [C] Energy production and conversion Mitochondrial carrier protein Protein CBG09959 {ECO:0000313|EMBL:CAP29483.1} OS=Caenorhabditis briggsae PE=3 SV=1 C Energy production and conversion Protein K11H3.3 [Caenorhabditis elegans] F15D3.6 gene3194 807 793 996 1723 1665 1871 64.56573 58.29219262 73.95481 129.20570109495 121.23436628 145.79980258148 1.83133627040393e-06 1.01156584260069 up -- -- -- -- -- [U] Intracellular trafficking, secretion, and vesicular transport PRELI-like family Protein F15D3.6 {ECO:0000313|EMBL:CAB02955.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein F15D3.6 [Caenorhabditis elegans] E03H4.8 gene3491 1908 2091 1816 701 715 766 124.669603341393 137.622234324 119.214451704667 46.8247756293 47.057680982 50.5394749614 3.19689190565572e-12 -1.42144513196206 down [R] General function prediction only Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; -- -- [U] Intracellular trafficking, secretion, and vesicular transport Coatomer WD associated region Protein E03H4.8 {ECO:0000313|EMBL:CAB04024.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein E03H4.8 [Caenorhabditis elegans] mboa-4 gene19627 85 80 78 33 34 42 4.052433 3.814897 3.75178 1.59344214 1.63644355671 2.0202725924 0.00429268239700192 -1.16358783128548 down [S] Function unknown -- -- -- [S] Function unknown MBOAT, membrane-bound O-acyltransferase family Protein MBOA-4, isoform b {ECO:0000313|EMBL:CCG28249.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein MBOA-4, isoform b [Caenorhabditis elegans] F35E2.5 gene3271 66 70 59 30 22 29 1.9465522890597 1.993996492327 1.7265349389 0.832710801674231 0.625115026078934 0.813541153 0.00303227773225757 -1.27552375708212 down -- -- -- -- -- -- -- Domain of unknown function (DUF316) Protein F35E2.5 {ECO:0000313|EMBL:CAB04281.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F35E2.5 [Caenorhabditis elegans] col-137 gene31124 535 478 335 178 108 60 24.9579 21.3702 14.82434 8.02159 4.54719 2.64648 2.83538943516458e-06 -1.97352293874889 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-137 {ECO:0000313|EMBL:CAB61143.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein COL-137 [Caenorhabditis elegans] C02F5.5 gene11691 64 67 60 30 30 27 15.5222 14.8295 13.5324 7.31492 6.92559 6.38126 0.00938644429612497 -1.14236397989382 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP09385.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein C02F5.5 [Caenorhabditis elegans] K10D11.6 gene20339 540 726 389 281 223 210 21.42599798 28.070161 14.52626 10.768476 8.512165 8.1892130018 0.00982161009089447 -1.22179852912877 down -- -- -- -- -- -- -- CUB-like domain Protein K10D11.6 {ECO:0000313|EMBL:CAB03525.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K10D11.6 [Caenorhabditis elegans] ZK673.1 gene7990 133 142 122 290 353 334 46.7261 45.2104 39.069 98.4381 107.414 116.1545 4.91843750910425e-06 1.29212019268449 up -- -- -- -- -- -- -- ShK domain-like Putative uncharacterized protein {ECO:0000313|EMBL:EFO86236.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein ZK673.1, isoform a [Caenorhabditis elegans] irg-3 gene33618 809 689 497 265 203 195 110.272653308342 87.45937875 63.794816 34.99431051765 26.548964 26.166013610186 1.26460204271964e-05 -1.59871004380608 down -- -- -- -- -- -- -- -- Protein IRG-3 {ECO:0000313|EMBL:CCD66101.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein IRG-3 [Caenorhabditis elegans] W05E10.1 gene37159 595 658 450 117 116 99 35.8937 40.2538 27.1686 7.25485 7.14964 6.15054 7.35228369982295e-15 -2.36719171790046 down -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Major Facilitator Superfamily Protein W05E10.1 {ECO:0000313|EMBL:CAB01247.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W05E10.1 [Caenorhabditis elegans] F48G7.7 gene33064 76 84 44 13 4 18 19.7021 20.0637 10.7457 3.54867 1.13067 4.65957 2.14924553378839e-05 -2.55098034659858 down -- -- -- -- -- -- -- ShK domain-like Protein F48G7.7 {ECO:0000313|EMBL:CCD70352.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F48G7.7 [Caenorhabditis elegans] lys-2 gene36429 11827 14811 14820 3616 2666 2563 1005.35 1212.37 1195.29 304.558 216.876 212.525 7.00845921956403e-31 -2.23708330828659 down -- -- -- -- -- -- -- -- Protein LYS-2 {ECO:0000313|EMBL:CAA16324.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein LYS-2 [Caenorhabditis elegans] ugt-63 gene34449 1047 1480 1047 437 285 233 46.0822 64.87303 45.90688 19.51752 12.66832 10.43439 3.08856240413184e-08 -1.9135938028675 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-63 {ECO:0000313|EMBL:CCD63017.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein UGT-63 [Caenorhabditis elegans] lin-46 gene37741 47 80 66 129 150 144 2.354071932659 3.8146479 2.998450261797 6.298090290087 7.350410879281 6.713980670817 0.00140450891318021 1.12550349466975 up [H] Coenzyme transport and metabolism Biological Process: molybdopterin cofactor biosynthetic process (GO:0032324);; -- -- [H] Coenzyme transport and metabolism MoeA N-terminal region (domain I and II) Protein LIN-46 {ECO:0000313|EMBL:CAB01440.2} OS=Caenorhabditis elegans PE=2 SV=1 V Defense mechanisms Protein LIN-46 [Caenorhabditis elegans] F54H5.5 gene6623 79 101 100 30 30 41 4.51467 4.70943 5.10872 2.125299 2.3412211 3.13885 0.000117541891693352 -1.47730246941885 down -- -- -- -- -- -- -- -- Protein F54H5.5 {ECO:0000313|EMBL:CCD68191.1} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein F54H5.5 [Caenorhabditis elegans] C23H5.8 gene13682 202 171 166 1045 1356 1785 23.6675577982 19.048268 17.329059985 117.411947803 143.4005294787 197.2528799745 7.6515320147047e-10 2.95098869212067 up -- -- -- -- -- -- -- -- Protein C23H5.8, isoform a {ECO:0000313|EMBL:CCD65346.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C23H5.8, isoform a [Caenorhabditis elegans] C08E3.13 gene4736 360 363 133 684 1185 1202 1319.476123722 1165.955331628 488.013103148 3455.78744334 4372.29064748529 5057.38098303384 0.000364067508416195 1.83597542113786 up -- -- -- -- -- -- -- -- Protein C08E3.13 {ECO:0000313|EMBL:CCD63678.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C08E3.1 [Caenorhabditis elegans] bigr-1 gene8235 186 192 120 495 482 466 22.88100749292 21.2821265986 13.53200404806 60.8154205715 53.7796824334 56.65510439291 2.86402891123582e-09 1.52649851752188 up [R] General function prediction only -- -- -- [R] General function prediction only Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like Protein F37H8.3, isoform a {ECO:0000313|EMBL:CAB04344.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F37H8.3, isoform a [Caenorhabditis elegans] grl-19 gene13264 783 657 279 22 108 38 218.427 168.682 76.7289 6.82071 28.6509 10.8185 0.000354792186125858 -3.36188675907028 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-19 {ECO:0000313|EMBL:CCD73170.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GRL-19 [Caenorhabditis elegans] F26D11.2 gene35532 452 436 214 36 98 36 15.02116 14.21777011 7.42103 1.1923749275 3.520696 1.2332477401 8.95680560628099e-05 -2.70412856622684 down -- -- -- -- -- -- -- -- Protein F26D11.2 {ECO:0000313|EMBL:CCD70048.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein F26D11.2 [Caenorhabditis elegans] sqt-2 gene4198 2497 2767 2194 5081 5080 5061 176.2793 188.0412 153.6446 347.60106 339.52752 337.61542 2.31707883807763e-07 1.02158760978651 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein SQT-2 {ECO:0000313|EMBL:CCD61131.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein SQT-2 [Caenorhabditis elegans] C33H5.2 gene18342 17 19 15 366 420 368 0.737117 0.826466 0.627407 15.4353 17.6758 15.645 2.06205941762064e-44 4.49245137638876 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Putative uncharacterized protein {ECO:0000313|EMBL:EFP05639.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 I Lipid transport and metabolism Protein C33H5.2 [Caenorhabditis elegans] ckb-4 gene33460 175 160 174 448 483 396 9.4591471296 8.8241602551 9.1357572066 25.0417754074 26.394206 21.2234610088 1.65515596003449e-07 1.37467563234501 up [M] Cell wall/membrane/envelope biogenesis -- -- -- [M] Cell wall/membrane/envelope biogenesis Choline/ethanolamine kinase;; Phosphotransferase enzyme family Protein CKB-4 {ECO:0000313|EMBL:CCD67444.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein CKB-4 [Caenorhabditis elegans] W03D8.9 gene521 329 478 553 226 209 235 20.9408247892 29.9740553648 34.73400408 14.611709312 13.1188249574 14.798962794 0.00324642449983859 -1.02797864970813 down -- -- -- -- -- -- -- Interactor of ZYG-11 Protein W03D8.9 {ECO:0000313|EMBL:CCD73382.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein W03D8.9 [Caenorhabditis elegans] Y113G7B.12 gene40514 284 265 251 637 567 598 4.420052 4.22319 3.9620856015 10.06456471 9.058717 9.646715 2.87072583067042e-06 1.16353747458904 up -- -- -- -- -- [R] General function prediction only Reverse transcriptase (RNA-dependent DNA polymerase);; Endonuclease/Exonuclease/phosphatase family;; Endonuclease-reverse transcriptase Protein Y113G7B.12 {ECO:0000313|EMBL:CAB76739.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y113G7B.12 [Caenorhabditis elegans] C06B3.7 gene38075 422 493 507 191 146 159 30.2435 35.3081158 35.40865 13.80625 10.43915 10.37217444 3.08524973271869e-09 -1.52745942974247 down -- -- -- -- -- -- -- -- Protein C06B3.7 {ECO:0000313|EMBL:CAB01117.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein C06B3.7 [Caenorhabditis elegans] oac-3 gene38070 32 37 28 6 7 2 1.21057825239 1.2276662439 1.01213661976 0.1615424619 0.266864183 0.07067375651 9.55081765111816e-07 -2.70268354508899 down -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-3 {ECO:0000313|EMBL:CAB01113.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein OAC-3 [Caenorhabditis elegans] Y5H2A.1 gene33520 3 0 0 29 39 45 0.834709 0 0.233781 7.90237 9.83351 11.9758 4.65978819418334e-14 5.22387441206399 up -- -- -- -- -- -- -- Caenorhabditis protein of unknown function, DUF282 Protein Y5H2A.1 {ECO:0000313|EMBL:CCD70997.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y5H2A.1 [Caenorhabditis elegans] F55G1.9 gene18217 1192 1180 974 528 496 345 92.8137 91.6519 75.2369 42.2852 38.5941 27.0296 4.06008538788617e-09 -1.2982810241499 down [E] Amino acid transport and metabolism -- K00286|0|cel:CELE_F55G1.9|F55G1.9; Protein F55G1.9; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] (A) Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Pyrroline-5-carboxylate reductase dimerisation;; NADP oxidoreductase coenzyme F420-dependent Pyrroline-5-carboxylate reductase {ECO:0000256|RuleBase:RU003903} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 S Function unknown Protein F55G1.9 [Caenorhabditis elegans] gsto-1 gene11589 171 218 157 443 470 375 15.4595400017889 20.1480800006138 15.055056 40.813031 43.96976 34.96241 3.8589593316453e-06 1.23017716517281 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; K00799|0|cel:CELE_C29E4.7|gsto-1; Protein GSTO-1; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT56590.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 F Nucleotide transport and metabolism Protein GSTO-1 [Caenorhabditis elegans] ZK355.3 gene5198 187 155 61 11 30 14 49.7029 38.1824 14.9145 2.96753 7.64716 3.74551 0.00366005570168701 -2.8810023258895 down -- -- -- -- -- -- -- -- Protein ZK355.3 {ECO:0000313|EMBL:CCD73705.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK355.3 [Caenorhabditis elegans] Y54G2A.13 gene13854 63 83 97 40 37 34 1.373612 1.758113968 2.02865180200782 0.84363637 0.76822468 0.72605634116963 0.00542273337020623 -1.13767797239682 down -- -- -- -- -- -- -- -- Protein Y54G2A.13 {ECO:0000313|EMBL:CCD83501.2} OS=Caenorhabditis elegans PE=4 SV=3 TV Signal transduction mechanisms;; Defense mechanisms Y54G2A.13 [Caenorhabditis elegans] grl-23 gene37574 16706 14412 6690 760 2106 1462 1457.03463055566 1260.68440621 600.15109144753 70.507319 188.032370840791 131.114231037029 0.000117541891693352 -3.13362999402488 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-23, isoform b {ECO:0000313|EMBL:CCE72012.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GRL-23, isoform b [Caenorhabditis elegans] K08E4.7 gene20007 48 38 45 16 15 24 3.03528 2.39243 2.80399 1.03786 0.988274 1.52308 0.00987840509808248 -1.25857053799013 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- BTB/POZ domain Protein K08E4.7 {ECO:0000313|EMBL:CAL49438.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K08E4.7 [Caenorhabditis elegans] Y40C5A.3 gene18151 6822 5302 2368 249 875 586 63.682442055987 47.2131457414724 20.7071104976587 1.99298902064536 7.6246463208867 4.94537393059775 0.0010030254614063 -3.08969296495174 down -- -- -- -- -- -- -- -- Protein Y40C5A.3, isoform m {ECO:0000313|EMBL:CDM63548.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Y40C5A.3, isoform m [Caenorhabditis elegans] tre-3 gene37175 887 854 769 1976 2102 2794 22.8419805163009 22.1510212327701 20.4081168585488 55.89794352829 59.4092153924239 80.27488701954 2.38276436856174e-07 1.44630887524977 up [G] Carbohydrate transport and metabolism Molecular Function: alpha,alpha-trehalase activity (GO:0004555);; Biological Process: trehalose metabolic process (GO:0005991);; K01194|0|cel:CELE_W05E10.4|tre-3; Protein TRE-3, isoform A; K01194 alpha,alpha-trehalase [EC:3.2.1.28] (A) Starch and sucrose metabolism (ko00500) [G] Carbohydrate transport and metabolism Trehalase Trehalase {ECO:0000256|RuleBase:RU361180} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein TRE-3, isoform b [Caenorhabditis elegans] C28D4.10 gene19047 61 39 26 2 6 8 37.0686563512 20.928292 14.7568167012 1.88701 3.584215 19.42915 0.00066264779197409 -2.98253265251149 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- Ubiquitin family Protein C28D4.10, isoform a {ECO:0000313|EMBL:CAE17728.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein C28D4.10 [Caenorhabditis elegans] pept-1 gene42886 9616 9680 5779 3895 3113 2340 191.8217 192.6601 113.8908 78.877 63.3998 47.348 0.00075724011382478 -1.43335738864082 down [E] Amino acid transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K14206|0|cel:CELE_K04E7.2|pept-1; Protein PEPT-1; K14206 solute carrier family 15 (oligopeptide transporter), member 1 (A) -- [E] Amino acid transport and metabolism POT family CRE-PEPT-1 protein {ECO:0000313|EMBL:EFO82401.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein PEPT-1 [Caenorhabditis elegans] R02C2.7 gene32945 132 165 111 53 76 64 56.8141 64.2253 46.031 25.516 30.8251 28.0218 0.00226204909464571 -1.08693613317492 down -- -- -- -- -- -- -- Domain of unknown function (DUF4440);; SnoaL-like domain;; SnoaL-like domain Protein R02C2.7 {ECO:0000313|EMBL:CCD68555.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein R02C2.7 [Caenorhabditis elegans] pes-8 gene43989 376 482 412 237 194 184 14.81934 18.55205 15.92094 9.18542 7.40105 7.0642 0.00010170596519824 -1.05439273400162 down -- -- -- -- -- -- -- -- Protein PES-8 {ECO:0000313|EMBL:CCD61934.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein PES-8 [Caenorhabditis elegans] cpr-8 gene33207 62 43 69 478 460 331 4.55771 3.00249 4.76054 35.77954 32.8956 25.34012 3.8387361489889e-19 2.85825522576365 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_W07B8.1|W07B8.1; Protein W07B8.1; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein W07B8.1 {ECO:0000313|EMBL:CCD74286.1} OS=Caenorhabditis elegans PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein W07B8.1 [Caenorhabditis elegans] W02H5.8 gene33636 253 181 176 1222 1332 1577 8.48713 6.14882 6.04698 43.1841 45.2944 53.6414 1.51375042268832e-32 2.75221516029496 up [G] Carbohydrate transport and metabolism Molecular Function: glycerone kinase activity (GO:0004371);; Biological Process: glycerol metabolic process (GO:0006071);; K00863|0|cel:CELE_W02H5.8|W02H5.8; Protein W02H5.8; K00863 dihydroxyacetone kinase [EC:2.7.1.29] (A) Glycerolipid metabolism (ko00561);; Carbon metabolism (ko01200) [G] Carbohydrate transport and metabolism Dak1 domain;; DAK2 domain Protein W02H5.8 {ECO:0000313|EMBL:CCD71686.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein W02H5.8 [Caenorhabditis elegans] W10C8.4 gene547 2359 2245 2112 5545 5561 5990 60.9810306427471 54.2556543962 58.8686542345 153.562557272467 143.9881800733 161.473009055811 3.15617469387557e-12 1.34050905371176 up -- -- -- -- -- -- -- Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain Protein W10C8.4, isoform a {ECO:0000313|EMBL:CCD73396.1} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein W10C8.4, isoform a [Caenorhabditis elegans] F36D3.8 gene39222 62 74 81 23 20 28 2.416685 2.754341796 3.961469 1.35727 0.941566 2.00345177184 8.26042513884987e-05 -1.61839764414763 down -- -- -- -- -- -- -- Protein of unknown function (DUF1248) Protein F36D3.8 {ECO:0000313|EMBL:CAB04320.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F36D3.8 [Caenorhabditis elegans] lbp-6 gene1638 2051 2178 1662 4629 4915 4876 588.4398 591.267 476.4372 1391.328 1350.739 1416.939 2.76992105306756e-11 1.28384769680181 up -- -- -- -- -- [I] Lipid transport and metabolism Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family CRE-LBP-6 protein {ECO:0000313|EMBL:EFP03185.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 C Energy production and conversion Protein LBP-6 [Caenorhabditis elegans] F09C6.11 gene39356 31 50 27 10 17 9 86.30312 86.62105 102.23036 2.29997997 42.0364700116678 42.88847 0.00903967461815668 -1.59231978487984 down -- -- -- -- -- -- -- -- Protein F09C6.11, isoform a {ECO:0000313|EMBL:CCA65548.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F09C6.11, isoform a [Caenorhabditis elegans] H02F09.3 gene41095 921 1029 475 175 166 169 10.749258 11.544214 5.4606881646 1.993471 1.9303158755 2.14872282276732 0.000357993929988224 -2.25798353890451 down -- -- -- -- -- -- -- -- Protein H02F09.3 {ECO:0000313|EMBL:CCD61779.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein H02F09.3 [Caenorhabditis elegans] pqn-98 gene33053 63 97 38 177 206 239 17.0082 23.928 9.65327 48.2434 51.8625 63.5256 1.39500903871421e-07 1.64422579581487 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein PQN-98 {ECO:0000313|EMBL:CCD71526.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein PQN-98 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_542 49 46 29 104 77 79 0.2424818 0.2478441 0.159026 0.636672 0.487192 0.483827 0.00907176064768936 1.05879754052085 up -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- -- Protein Y113G7C.1 {ECO:0000313|EMBL:CAA22059.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones PREDICTED: tyrosine-protein phosphatase non-receptor type 22 isoform X3 [Ailuropoda melanoleuca] gpdh-2 gene12260 4903 4174 3903 8911 9551 10653 273.51688 236.96327 221.78864 527.26063 546.40268 619.091904 4.07592044378406e-09 1.15811444345515 up [C] Energy production and conversion Molecular Function: glycerol-3-phosphate dehydrogenase [NAD+] activity (GO:0004367);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: glycerol-3-phosphate catabolic process (GO:0046168);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; K00006|0|cbr:CBG09958|Cbr-gpdh-2; C. briggsae CBR-GPDH-2 protein; K00006 glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] (A) Glycerophospholipid metabolism (ko00564) [C] Energy production and conversion NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Glycerol-3-phosphate dehydrogenase [NAD(+)] {ECO:0000256|RuleBase:RU361243} OS=Caenorhabditis elegans PE=3 SV=1 C Energy production and conversion Protein GPDH-2, isoform b [Caenorhabditis elegans] nhr-127 gene39107 22 18 40 102 94 85 1.161299 1.003029 1.94992852 5.84903 4.97128 5.04561 2.4113056469715e-06 1.80557469457707 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) CRE-NHR-127 protein {ECO:0000313|EMBL:EFP12763.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 R General function prediction only Protein NHR-127 [Caenorhabditis elegans] Y55F3AM.11 gene13465 210 223 155 102 64 91 11.20487531 11.2195185251 8.3003003693 5.944528 3.559453 4.824699 0.000182253475717796 -1.20276135891638 down -- -- -- -- -- -- -- Methyltransferase domain;; Methyltransferase FkbM domain Protein Y55F3AM.11 {ECO:0000313|EMBL:CCD74069.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y55F3AM.11 [Caenorhabditis elegans] sodh-1 gene37245 3941 2959 4418 30149 35536 53900 250.834 185.024 278.929 1928.3 2233.02 3398.93 1.04390816941929e-08 3.39576451933753 up [R] General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K13953|0|cel:CELE_K12G11.3|sodh-1; Protein SODH-1; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase Protein CBR-SODH-1 {ECO:0000313|EMBL:CAP39759.1} OS=Caenorhabditis briggsae PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein SODH-1 [Caenorhabditis elegans] pho-4 gene6016 589 664 520 1160 1319 1629 27.2187 30.5885 23.9985 53.6899 60.5514 75.2453 1.79668814682478e-06 1.20557510678335 up -- -- Molecular Function: acid phosphatase activity (GO:0003993);; -- -- [I] Lipid transport and metabolism Histidine phosphatase superfamily (branch 2) Protein PHO-4 {ECO:0000313|EMBL:CCD68012.1} OS=Caenorhabditis elegans PE=4 SV=5 I Lipid transport and metabolism Protein PHO-4 [Caenorhabditis elegans] hacd-1 gene33272 495 619 505 7756 9563 12151 26.577644 32.74658 26.696764543 415.849901 504.520792428 641.290361498 2.6807248273057e-21 4.17997941136502 up [I] Lipid transport and metabolism Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Biological Process: fatty acid metabolic process (GO:0006631);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00022|0|cel:CELE_R09B5.6|hacd-1; Protein HACD-1; K00022 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] (A) Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Butanoate metabolism (ko00650);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; NADP oxidoreductase coenzyme F420-dependent;; NAD binding domain of 6-phosphogluconate dehydrogenase Protein HACD-1 {ECO:0000313|EMBL:CCD68882.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein HACD-1 [Caenorhabditis elegans] F49C12.4 gene18869 21 31 9 461 465 365 1.55465700000544 2.279363 0.669763 33.65338 33.19059 26.45813 1.76134859777087e-45 4.39447391126827 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F49C12.4 {ECO:0000313|EMBL:CAA92509.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49C12.4 [Caenorhabditis elegans] K07C5.2 gene36451 378 452 449 2033 2240 2628 30.6144 36.373 35.6709 162.715 179.995 213.223 3.08939109513868e-29 2.42535517602719 up [R] General function prediction only -- -- -- [R] General function prediction only Aldo/keto reductase family Protein K07C5.2 {ECO:0000313|EMBL:CAA94895.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K07C5.2 [Caenorhabditis elegans] F08F3.4 gene34538 741 835 1040 347 250 154 45.7977 51.0128 62.9316 21.1546 15.3273 9.49643 1.7965687996939e-09 -1.80980332113217 down [MG] Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; K15789|0|cel:CELE_F08F3.4|F08F3.4; Protein F08F3.4; K15789 threonine 3-dehydrogenase [EC:1.1.1.103] (A) Glycine, serine and threonine metabolism (ko00260) [R] General function prediction only NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; Male sterility protein;; 3-beta hydroxysteroid dehydrogenase/isomerase family Protein F08F3.4 {ECO:0000313|EMBL:CCD65594.1} OS=Caenorhabditis elegans PE=4 SV=2 Q Secondary metabolites biosynthesis, transport and catabolism Protein F08F3.4 [Caenorhabditis elegans] M6.11 gene40877 164 131 69 2 30 7 59.9491 42.8128 23.1423 1.06968 10.3446 2.80065 0.000107599913008318 -3.22826123411606 down -- -- Molecular Function: carbohydrate binding (GO:0030246);; -- -- [W] Extracellular structures Galactoside-binding lectin Galectin {ECO:0000256|RuleBase:RU102079} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein M6.11 [Caenorhabditis elegans] ugt-17 gene36350 115 111 122 738 731 745 4.758472 4.72500439725 5.1360405423 31.25306 31.08547 31.75333 1.19197489406316e-27 2.66211574689532 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-17, isoform b {ECO:0000313|EMBL:CAN86590.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein UGT-17, isoform b [Caenorhabditis elegans] F46C5.1 gene7427 138 167 166 541 777 1292 54.31596 66.13338 70.21467 244.2995 324.591 560.5541 0.00297051535499357 2.46561642003039 up -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFO85988.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein F46C5.1 [Caenorhabditis elegans] fat-5 gene39723 555 504 265 1355 1434 1018 27.6399570000003 23.16446233 13.83662958895 68.7888363525 67.6684801298 49.0081500000073 4.70038965199738e-07 1.51448061696752 up [I] Lipid transport and metabolism -- K00507|0|cel:CELE_W06D12.3|fat-5; Protein FAT-5; K00507 stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] (A) Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) [I] Lipid transport and metabolism Fatty acid desaturase CBN-FAT-5 protein {ECO:0000313|EMBL:EGT49222.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 I Lipid transport and metabolism Protein FAT-5 [Caenorhabditis elegans] ugt-9 gene34372 447 576 339 106 102 94 18.3311122931 23.615092 13.7704089414 4.3874019467 4.21942748808 3.88127541346 2.87279848410008e-07 -2.18134794670476 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-9, isoform a {ECO:0000313|EMBL:CCD66997.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein UGT-9, isoform a [Caenorhabditis elegans] F17C11.11 gene36729 1968 2038 2409 802 771 826 158.876000000419 167.5745 200.8013 66.72391 64.7616500003405 69.5249 1.54982258298072e-12 -1.42611734234574 down -- -- -- -- -- -- -- -- Protein F17C11.11, isoform a {ECO:0000313|EMBL:CAC35886.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F17C11.11, isoform a [Caenorhabditis elegans] F38B2.2 gene44629 77 54 53 23 20 34 15.6835 10.1813 10.4563 4.98206 3.95249 7.02799 0.00391770569149174 -1.26391323140976 down -- -- -- -- -- -- -- -- Protein F38B2.2 {ECO:0000313|EMBL:CAA90362.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F38B2.2 [Caenorhabditis elegans] clec-21 gene4715 156 120 75 32 40 19 8.12413 6.12777 3.84507 1.68372 2.08763 0.999379 0.00145661376288394 -1.95712698209413 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain;; Chordopoxvirus A33R protein;; UL45 protein Protein CLEC-21 {ECO:0000313|EMBL:CCD63699.1} OS=Caenorhabditis elegans PE=4 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-21 [Caenorhabditis elegans] T07A5.1 gene12419 93 114 102 32 38 59 5.4923682605 6.66717487366 5.94019656464 1.884467715 2.212791 3.432927 0.000779986602299682 -1.26577068799653 down -- -- -- -- -- -- -- LicD family Protein CBG24613 {ECO:0000313|EMBL:CAP21175.2} OS=Caenorhabditis briggsae PE=4 SV=2 R General function prediction only Protein T07A5.1 [Caenorhabditis elegans] C08A9.3 gene46577 168 129 53 14 23 22 5.025270859 3.807661033 1.602049 0.424167956 0.6867243328 0.660334785 0.00959713941051314 -2.57625093969965 down -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: dsRNA transport (GO:0033227);; Molecular Function: RNA transmembrane transporter activity (GO:0051033);; -- -- -- -- dsRNA-gated channel SID-1 Protein C08A9.3, isoform b {ECO:0000313|EMBL:CCD63620.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C08A9.3, isoform b [Caenorhabditis elegans] col-71 gene5451 4574 4929 4910 2332 1808 1785 180.379 179.412 181.27 87.7974 65.4732 65.4501 2.23448624286668e-11 -1.2908397904438 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-71 {ECO:0000313|EMBL:CCD64720.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-71 [Caenorhabditis elegans] nhr-156 gene34073 59 56 45 129 100 97 3.38662104365 3.200460477405 2.58944110121 7.6265 5.681379 5.617028 0.00789738319918616 1.01782601267803 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) CBN-NHR-284 protein {ECO:0000313|EMBL:EGT31079.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 K Transcription CBN-NHR-284 protein [Caenorhabditis brenneri] hmit-1.1 gene39987 430 471 432 7591 7965 9338 14.249838 14.949320192 14.47438247 271.7202 277.1607 330.2908 4.30673015101786e-84 4.21616765941825 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; K08150|0|cel:CELE_Y51A2D.4|hmit-1.1; Protein HMIT-1.1; K08150 MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 (A) -- [R] General function prediction only Sugar (and other) transporter;; Major Facilitator Superfamily Protein HMIT-1.1 {ECO:0000313|EMBL:CAA16400.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein HMIT-1.1 [Caenorhabditis elegans] Y105C5B.11 gene28887 36 39 37 12 23 10 0.73957896401 0.79737197264 0.829765 0.25289036446 0.500614 0.216374327 0.00967265495763712 -1.32264575847285 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Ring finger domain Protein Y105C5B.11, isoform b {ECO:0000313|EMBL:CCO25658.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y105C5B.11, isoform b [Caenorhabditis elegans] gst-16 gene8952 1036 993 902 196 173 222 143.1754 128.7718 119.1657 26.90136 22.36962 30.05577 2.60815663424785e-24 -2.3176472725225 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-16 {ECO:0000313|EMBL:CAB02291.1} OS=Caenorhabditis elegans PE=1 SV=1 O Posttranslational modification, protein turnover, chaperones Protein GST-16 [Caenorhabditis elegans] Y9C9A.16 gene14770 216 151 103 291 337 422 7.6919416 5.66412758600049 3.65892485964234 10.3231916015 11.5069625787699 14.8214137833 0.0015622481474418 1.15203676085782 up [R] General function prediction only Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [C] Energy production and conversion -- Protein Y9C9A.16, isoform b {ECO:0000313|EMBL:CCM09386.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y9C9A.16, isoform b [Caenorhabditis elegans] T28A11.17 gene33863 274 221 87 16 14 25 17.99661194561 13.16435485295 3.5589485779 0.606155446862 0.422060196034 0.64668346478 0.00101632628120277 -3.41144427161001 down -- -- -- -- -- -- -- Peptidase family M13 Protein T28A11.17 {ECO:0000313|EMBL:CCD70573.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein T28A11.17 [Caenorhabditis elegans] ZK228.4 gene39976 3040 3632 2688 755 605 314 197.3481 219.4375 173.52264 47.61323 35.61407 21.663492 1.95065648796411e-20 -2.49324756425135 down [KR] Transcription;; General function prediction only Molecular Function: N-acetyltransferase activity (GO:0008080);; -- -- -- -- Protein of unknown function (DUF1248);; Acetyltransferase (GNAT) domain Protein ZK228.4, isoform b {ECO:0000313|EMBL:CAN99701.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein ZK228.4, isoform b [Caenorhabditis elegans] amt-1 gene42165 78 43 24 473 600 732 3.57857 1.99464 1.11929 22.3025 27.5017 33.5378 5.6897500527281e-18 3.62979087690977 up [P] Inorganic ion transport and metabolism Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; K03320|0|cel:CELE_C05E11.4|amt-1; Protein AMT-1; K03320 ammonium transporter, Amt family (A) -- [P] Inorganic ion transport and metabolism Ammonium Transporter Family Protein CBR-AMT-1 {ECO:0000313|EMBL:CAP32998.1} OS=Caenorhabditis briggsae PE=4 SV=1 S Function unknown Protein AMT-1 [Caenorhabditis elegans] M60.7 gene43583 523 528 476 186 243 318 22.9681 22.29444 20.34778 7.82648 10.4954 13.78169 6.6798687579899e-05 -1.03754962062802 down [R] General function prediction only Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; -- -- [R] General function prediction only Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box Protein M60.7 {ECO:0000313|EMBL:CCD69430.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown hypothetical protein M60.7 - Caenorhabditis elegans col-54 gene1317 410 403 253 883 770 769 28.202464114 28.093629223 17.6111989643 61.3423927 52.683571 53.01627447 5.27385655976996e-07 1.1752402258494 up -- -- Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-54 {ECO:0000313|EMBL:CCD66436.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein COL-54 [Caenorhabditis elegans] Y54E2A.7 gene9265 65 51 76 23 27 32 3.41198 2.58849 4.01723 1.2637 1.42617 1.69765 0.00443592348797095 -1.23361492998106 down -- -- -- -- -- -- -- -- Protein Y54E2A.7 {ECO:0000313|EMBL:CAA21679.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Y54E2A.7 [Caenorhabditis elegans] ZK488.6 gene33050 84 80 97 16 7 0 3.32527 3.0869 3.72074 0.632816 0.286268 0.0382565 6.45638907410771e-16 -3.51824861002918 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein ZK488.6 {ECO:0000313|EMBL:CCD71525.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein ZK488.6 [Caenorhabditis elegans] oac-15 gene39078 15 7 10 111 111 149 0.493515 0.22457585 0.322094 3.639089 3.542732 4.822676 3.8387361489889e-19 3.52776916310251 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-15 {ECO:0000313|EMBL:CAB07360.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein OAC-15 [Caenorhabditis elegans] mpc-1 gene10456 717 619 615 1707 1907 1979 221.0022 174.5547 186.573 570.424 566.815 621.194 1.66289658753068e-13 1.51212484834796 up -- -- Cellular Component: mitochondrial inner membrane (GO:0005743);; Biological Process: mitochondrial pyruvate transport (GO:0006850);; -- -- [S] Function unknown Uncharacterised protein family (UPF0041) Putative uncharacterized protein {ECO:0000313|EMBL:EGT51965.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 B Chromatin structure and dynamics Protein R07E5.13 [Caenorhabditis elegans] C32H11.9 gene20317 4325 5390 4447 153 131 83 288.83 360.303 292.566 10.2334 8.8045 5.63631 1.67505971584316e-98 -5.27923824815238 down -- -- -- -- -- -- -- CUB-like domain Protein C32H11.9 {ECO:0000313|EMBL:CAB05135.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C32H11.9 [Caenorhabditis elegans] C54F6.5 gene35377 51 57 45 176 209 391 640.588877000033 360.634815000001 2.6678399894 21.1539026265 22.006657023 149.8406186023 0.00546493537527761 2.33717086024264 up -- -- -- -- -- -- -- -- Protein C54F6.5 {ECO:0000313|EMBL:CCD62987.2} OS=Caenorhabditis elegans PE=4 SV=3 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures C54F6.5 [Caenorhabditis elegans] npa-1 gene35186 16157 13874 9307 24947 26416 30843 214.7748 196.5427 130.1598 340.5258 342.6615 406.6118 3.3744393291567e-06 1.05555299815976 up -- -- -- -- -- -- -- Rab3 GTPase-activating protein catalytic subunit;; Phage uncharacterised protein (Phage_XkdX);; Protein of unknown function (DUF3775);; Drug resistance and apoptosis regulator;; Anti-Sigma Factor A;; Maintenance of mitochondrial structure and function Protein NPA-1, isoform a {ECO:0000313|EMBL:CCD70075.1} OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein NPA-1, isoform a [Caenorhabditis elegans] ant-1.4 gene18579 162 200 181 82 88 83 13.6625 16.4862 14.9327 7.15497 7.32509 6.99175 0.000776396163137581 -1.10902851439592 down -- -- -- K05863|0|cel:CELE_T01B11.4|ant-1.4; Protein ANT-1.4; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A) Calcium signaling pathway (ko04020) [C] Energy production and conversion Mitochondrial carrier protein Protein ANT-1.4 {ECO:0000313|EMBL:CCD65922.1} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein ANT-1.4 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_738 0 0 4 105 121 23 8.39442e-05 0.00044094 0.0733623 1.74967 1.98332 0.383508 0.00042804527558549 5.9551247234823 up -- -- -- -- -- -- -- -- Protein T20F7.5 {ECO:0000313|EMBL:CCD71065.1} OS=Caenorhabditis elegans PE=1 SV=3 I Lipid transport and metabolism -- F01D4.8 gene19360 226 170 109 506 562 739 9.95559800004276 6.78319834864 4.779511 24.2474570021482 26.30812698105 35.22213086334 1.42964035375566e-07 1.83166859281226 up [E] Amino acid transport and metabolism -- -- -- [E] Amino acid transport and metabolism Pyridoxal-phosphate dependent enzyme Protein F01D4.8 {ECO:0000313|EMBL:CAB02888.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F01D4.8 [Caenorhabditis elegans] C17F4.12 gene5335 4 13 15 52 83 82 0.23730015 1.605794 3.637465 10.6687 12.28994 18.59381 7.30898073675579e-09 2.75733846431355 up -- -- -- -- -- -- -- -- Protein C17F4.12 {ECO:0000313|EMBL:CCD64915.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C17F4.12 [Caenorhabditis elegans] prk-1 gene11294 781 731 651 1206 1346 1908 24.41081 23.353324 19.7953651000025 36.49311065989 40.477196 56.68070735 0.00467907751096942 1.03755126325835 up [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase;; Kinase-like Protein PRK-1, isoform d {ECO:0000313|EMBL:CCO25652.1} OS=Caenorhabditis elegans PE=3 SV=1 T Signal transduction mechanisms Protein PRK-1, isoform d [Caenorhabditis elegans] M02D8.5 gene43804 80 61 85 233 229 275 2.29834 1.71329235496 2.289814810782 6.64158 6.3846756 7.55784 1.35788349817235e-08 1.69838707427148 up -- -- -- -- -- -- -- CUB domain Protein M02D8.5 {ECO:0000313|EMBL:CCD68799.1} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein M02D8.5 [Caenorhabditis elegans] daf-9 gene42777 144 167 152 327 363 442 4.21486032597 4.86987600025065 4.1069678301566 9.219196 10.47836 13.054719 2.70544584291606e-06 1.28328849109408 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 CRE-DAF-9 protein {ECO:0000313|EMBL:EFO82524.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 K Transcription Protein DAF-9, isoform a [Caenorhabditis elegans] T22F3.8 gene33998 76 107 76 23 30 38 3.97165 5.51626 3.93116 1.24627 1.57652 2.01618 0.000109111904288833 -1.51496343898687 down [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein T22F3.8 {ECO:0000313|EMBL:CCD70904.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein T22F3.8 [Caenorhabditis elegans] R12H7.4 gene45281 20 16 7 35 47 39 1.31356 1.04217 0.467097 2.26819 2.96236 2.53785 0.0026239489614366 1.48408481100274 up -- -- -- -- -- -- -- -- Protein R12H7.4 {ECO:0000313|EMBL:CAA90634.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein R12H7.4 [Caenorhabditis elegans] R193.2 gene40999 510 624 392 2759 2506 1786 4.5192031 5.303347 3.312754802 23.32578 21.22430878 15.14438 6.53903925402982e-11 2.19898787924533 up -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain;; SEA domain Protein R193.2 {ECO:0000313|EMBL:CCD63165.2} OS=Caenorhabditis elegans PE=4 SV=5 R General function prediction only Protein R193.2 [Caenorhabditis elegans] col-41 gene46003 2952 3021 1782 9700 9414 8917 82.7835 80.7432 48.0061 264.753 253.401 238.371 4.68370742140917e-22 1.84530960821734 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-41 {ECO:0000313|EMBL:CAA96674.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-41 [Caenorhabditis elegans] F15H10.5 gene36489 328 331 125 7 15 17 27.1301 27.8095 10.4515 0.628726 1.32535 1.4658 9.77973555371638e-06 -4.33550959073088 down -- -- -- -- -- -- -- -- Protein F15H10.5 {ECO:0000313|EMBL:CAA98262.4} OS=Caenorhabditis elegans PE=4 SV=4 DO Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones Protein F15H10.5 [Caenorhabditis elegans] E02C12.8 gene36077 317 361 302 122 134 92 33.46931972 25.7091178907 18.3105649289 7.13564118688 9.61664836007746 6.195362127 8.26002803744676e-08 -1.50186219728315 down -- -- -- -- -- -- -- Protein of unknown function (DUF1679) Protein E02C12.8, isoform c {ECO:0000313|EMBL:CCD68594.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only E02C12.8, isoform c [Caenorhabditis elegans] pccb-1 gene41609 7200 6808 6832 16367 16658 17442 253.769306455034 236.50513981711 238.783333331 587.315243659074 586.554151641081 614.67817591307 2.01851162547276e-10 1.26858145235347 up [I] Lipid transport and metabolism -- K01966|0|cel:CELE_F52E4.1|pccb-1; Protein PCCB-1, isoform A; K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] (A) Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640) [EI] Amino acid transport and metabolism;; Lipid transport and metabolism Carboxyl transferase domain Protein PCCB-1, isoform a {ECO:0000313|EMBL:CCD66477.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein PCCB-1, isoform a [Caenorhabditis elegans] F41E6.5 gene35773 313 293 335 1356 1708 2336 19.510614 18.75493 21.32036 87.57246 107.93139 149.38105 1.31215945677994e-07 2.51494302834658 up [C] Energy production and conversion Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K11517|0|cbr:CBG01477|Hypothetical protein CBG01477; K11517 (S)-2-hydroxy-acid oxidase [EC:1.1.3.15] (A) Glyoxylate and dicarboxylate metabolism (ko00630);; Peroxisome (ko04146) [C] Energy production and conversion FMN-dependent dehydrogenase;; Nitronate monooxygenase;; IMP dehydrogenase / GMP reductase domain;; Thiazole biosynthesis protein ThiG Protein F41E6.5, isoform b {ECO:0000313|EMBL:CCD64095.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein F41E6.5, isoform b [Caenorhabditis elegans] R04B5.6 gene36342 140 135 76 10 20 6 10.7297 10.1869 5.79948 0.819831 1.56134 0.526343 4.46388654598129e-08 -3.29396902872457 down [ER] Amino acid transport and metabolism;; General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K00008|0|cel:CELE_R04B5.6|R04B5.6; Protein R04B5.6; K00008 L-iditol 2-dehydrogenase [EC:1.1.1.14] (A) Pentose and glucuronate interconversions (ko00040);; Fructose and mannose metabolism (ko00051) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase Protein R04B5.6 {ECO:0000313|EMBL:CAA94842.1} OS=Caenorhabditis elegans PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein R04B5.6 [Caenorhabditis elegans] F22B5.4 gene7295 289 269 220 530 653 775 59.6438 49.8176 39.1193 106.6267 118.5641 146.7313 2.08913401938334e-06 1.32476039149337 up -- -- -- -- -- -- -- -- Protein F22B5.4 {ECO:0000313|EMBL:CAA90356.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F22B5.4 [Caenorhabditis elegans] tre-5 gene4213 432 416 538 180 194 219 12.5783 12.1604 15.6823 5.32244 5.7195 6.46597 2.47652117781274e-06 -1.23134212535954 down [G] Carbohydrate transport and metabolism Molecular Function: alpha,alpha-trehalase activity (GO:0004555);; Biological Process: trehalose metabolic process (GO:0005991);; K01194|0|cel:CELE_C23H3.7|tre-5; Protein TRE-5; K01194 alpha,alpha-trehalase [EC:3.2.1.28] (A) Starch and sucrose metabolism (ko00500) [G] Carbohydrate transport and metabolism Trehalase;; Amylo-alpha-1,6-glucosidase Trehalase {ECO:0000256|RuleBase:RU361180} OS=Caenorhabditis elegans PE=2 SV=1 K Transcription Protein TRE-5 [Caenorhabditis elegans] pyc-1 gene37221 7860 6776 9434 15529 16798 18763 117.649551553 104.154290579 137.910562905 240.824223575 248.309623404 282.051931344 1.19384503518966e-07 1.0792081878311 up -- -- Molecular Function: catalytic activity (GO:0003824);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; K01958|0|cbr:CBG23262|Cbr-pyc-1; C. briggsae CBR-PYC-1 protein; K01958 pyruvate carboxylase [EC:6.4.1.1] (A) Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [C] Energy production and conversion Carbamoyl-phosphate synthase L chain, ATP binding domain;; Conserved carboxylase domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; HMGL-like;; ATP-grasp domain;; Biotin-requiring enzyme;; D-ala D-ala ligase C-terminus;; ATP-grasp domain;; Biotin-lipoyl like;; RimK-like ATP-grasp domain Pyruvate carboxylase {ECO:0000256|PIRNR:PIRNR001594} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 V Defense mechanisms Protein PYC-1, isoform a [Caenorhabditis elegans] cyp-35A4 gene34129 71 141 74 18 13 0 3.24905 6.59046 3.38698 0.836472 0.649576 0.0452444 0.000174764346957159 -3.21818985729547 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17957|0|cel:CELE_C49G7.8|cyp-35A4; Protein CYP-35A4; K17957 cytochrome P450, family 35 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-35A4 {ECO:0000313|EMBL:CCD67691.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein CYP-35A4 [Caenorhabditis elegans] Y110A2AL.2 gene5185 39 28 27 61 90 74 1.244081 0.880695000015238 0.822878000392635 1.884475 2.74765 2.19963 0.00250085187802696 1.2518410351347 up -- -- -- -- -- -- -- CC domain Protein Y110A2AL.2 {ECO:0000313|EMBL:CCD72971.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y110A2AL.2 [Caenorhabditis elegans] asp-16 gene40150 61 50 26 9 8 15 3.39896 2.64283 1.40578 0.523319 0.447241 0.836108 0.00399243893518043 -2.10541966098514 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-16 {ECO:0000313|EMBL:CAD31820.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein ASP-16 [Caenorhabditis elegans] pck-1 gene9394 11572 9803 10296 26266 27630 34799 289.019204 235.986376084325 254.88775118 658.42872896 670.91332 838.84124334 3.86244556774313e-11 1.47879338069087 up [C] Energy production and conversion Molecular Function: phosphoenolpyruvate carboxykinase activity (GO:0004611);; Biological Process: gluconeogenesis (GO:0006094);; K01596|0|cbr:CBG00466|Hypothetical protein CBG00466; K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] (A) Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; FoxO signaling pathway (ko04068) [C] Energy production and conversion Phosphoenolpyruvate carboxykinase Protein PCK-1, isoform a {ECO:0000313|EMBL:CCD71753.1} OS=Caenorhabditis elegans PE=3 SV=2 W Extracellular structures Protein PCK-1, isoform a [Caenorhabditis elegans] ZK813.2 gene41748 946 1142 1358 509 550 359 664.893 705.231 883.346 393.321 357.385 260.894 1.4594206446531e-06 -1.28871777761038 down -- -- -- -- -- -- -- -- Protein ZK813.2 {ECO:0000313|EMBL:CCD63035.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK813.2 [Caenorhabditis elegans] K01A6.7 gene19864 83 76 44 360 497 505 26.94226 26.88693 20.565705 170.79289 112.7578 169.72 1.35378426343785e-17 2.73882234813596 up -- -- -- -- -- -- -- -- Protein K01A6.7 {ECO:0000313|EMBL:CBI63226.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K01A6.7 [Caenorhabditis elegans] tag-293 gene35294 4 4 8 197 225 318 0.442806 0.482424 0.871861 21.3092 23.256 33.347 3.30671304010975e-20 5.52656935638704 up -- -- -- -- -- -- -- ShK domain-like Protein TAG-293 {ECO:0000313|EMBL:CCD62698.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein TAG-293 [Caenorhabditis elegans] clec-48 gene39844 628 497 370 1021 1386 2008 43.95249 33.0182 24.85781 70.69479 92.87613 134.9405 0.00646446645648286 1.55589725835697 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-48 {ECO:0000313|EMBL:CAB03881.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-48 [Caenorhabditis elegans] dhs-2 gene1175 220 212 195 701 1008 1616 15.3813712197 14.1911574624792 12.8758008317 46.6396355525 66.5453555124145 106.491018274403 0.00196297444928704 2.4015714164708 up [IQR] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only -- -- -- [QR] Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase Protein DHS-2, isoform a {ECO:0000313|EMBL:CCD65438.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein DHS-2, isoform a [Caenorhabditis elegans] mul-1 gene14224 1234 1482 1081 312 276 145 136.4716 138.903 106.4465 32.24824 26.26868 15.86699 5.48776337749325e-18 -2.38263084869655 down -- -- -- -- -- -- -- ShK domain-like Protein MUL-1 {ECO:0000313|EMBL:CCD66748.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F49F1.6 [Caenorhabditis elegans] K06H6.2 gene33047 423 390 419 51 23 5 28.6486 24.8996 27.2782 3.44255 1.50521 0.384517 2.08439055078732e-39 -3.97616762958855 down -- -- -- -- -- -- -- Methyltransferase domain;; Methyltransferase FkbM domain Protein K06H6.2 {ECO:0000313|EMBL:CCD64473.1} OS=Caenorhabditis elegans PE=4 SV=1 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K06H6.2 [Caenorhabditis elegans] C14C6.6 gene33032 170 160 161 22 13 2 5.85495 5.31932 5.311971 0.757097 0.4340606567 0.0977264287 9.81288724712558e-24 -3.74272526887167 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C14C6.6 {ECO:0000313|EMBL:CCD64462.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein C14C6.6 [Caenorhabditis elegans] C18H9.5 gene6645 113 138 95 25 32 65 6.34865 7.86729 5.38526 1.431651 1.861744 3.79512 0.000162227197666664 -1.50885809259673 down [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily;; Sugar (and other) transporter Protein C18H9.5 {ECO:0000313|EMBL:CCD65264.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C18H9.5 [Caenorhabditis elegans] mltn-1 gene8869 489 383 585 1473 1622 2340 11.186936049254 8.777738034 13.31238781223 34.5385500098766 36.846065001456 53.822304111 5.82319721366668e-06 1.89345985515059 up -- -- -- -- -- -- -- Moulting cycle Protein MLTN-1 {ECO:0000313|EMBL:CAE17802.2} OS=Caenorhabditis elegans PE=4 SV=2 L Replication, recombination and repair Protein MLTN-1 [Caenorhabditis elegans] clec-2 gene5237 3467 4233 1892 44 31 0 167.758 195.789 88.632 2.16506 1.47024 0 1.48040908013394e-15 -7.0123050966987 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-2 {ECO:0000313|EMBL:CCD61973.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-2 [Caenorhabditis elegans] nspc-9 gene45016 260 243 289 93 96 97 421.1408 321.7978 395.132 145.0325 138.9242 159.1454 5.20131864348039e-07 -1.47665930676899 down -- -- -- -- -- -- -- -- Protein NSPC-9 {ECO:0000313|EMBL:CAA92174.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein NSPC-9 [Caenorhabditis elegans] col-62 gene1862 406 500 623 272 211 218 15.14718 18.97808 23.36655 9.39943 8.00447 8.84711 0.000163745399310726 -1.13272312947985 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-62 {ECO:0000313|EMBL:CAB01958.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-62 [Caenorhabditis elegans] scl-6 gene20362 49 33 44 118 97 98 7.1159 4.55093 5.99616 17.2981 13.2968 14.0823 0.00051744011283305 1.30432646419061 up [S] Function unknown -- -- -- [S] Function unknown Cysteine-rich secretory protein family Protein SCL-6 {ECO:0000313|EMBL:CAA94330.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein SCL-6 [Caenorhabditis elegans] H25K10.1 gene30026 382 464 315 82 81 56 14.767396 17.061917 12.582298 3.329088 2.8898524 2.236416 4.72134063275198e-14 -2.41511153820216 down [R] General function prediction only Molecular Function: acid phosphatase activity (GO:0003993);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; -- -- [G] Carbohydrate transport and metabolism Calcineurin-like phosphoesterase;; Iron/zinc purple acid phosphatase-like protein C;; Calcineurin-like phosphoesterase superfamily domain;; PhoD-like phosphatase Purple acid phosphatase {ECO:0000256|RuleBase:RU361203} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein H25K10.1 [Caenorhabditis elegans] sdz-35 gene5316 38 51 58 16 15 8 4.90822 6.46015 7.261 2.0929 1.98699 1.12829 3.2532111272609e-05 -1.922780079622 down -- -- Molecular Function: protein binding (GO:0005515);; Biological Process: protein homooligomerization (GO:0051260);; -- -- [P] Inorganic ion transport and metabolism BTB/POZ domain;; BTB/POZ domain Protein SDZ-35 {ECO:0000313|EMBL:CCD64936.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein SDZ-35 [Caenorhabditis elegans] W03B1.3 gene14304 149 147 101 279 312 358 6.935969 4.893299 4.23338359864 9.438176 8.264739 11.52296 1.19700177339211e-05 1.24991829204791 up -- -- -- -- -- -- -- -- Protein W03B1.3 {ECO:0000313|EMBL:CCD71907.1} OS=Caenorhabditis elegans PE=4 SV=3 J Translation, ribosomal structure and biogenesis Protein W03B1.3 [Caenorhabditis elegans] K07A1.4 gene2531 56 46 69 21 26 25 5.17619 4.16972 6.30625 2.01172 2.39466 2.33902 0.00516156245228303 -1.2544135596036 down -- -- -- -- -- -- -- -- Protein K07A1.4 {ECO:0000313|EMBL:CAB03166.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K07A1.4 [Caenorhabditis elegans] grd-9 gene34723 596 507 294 27 93 53 15.2226 12.8409 7.41987 0.680709 2.33696 1.3462 1.90496736563789e-06 -3.01985687289702 down -- -- -- -- -- -- -- Ground-like domain Protein GRD-9 {ECO:0000313|EMBL:CCD62894.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein GRD-9 [Caenorhabditis elegans] Y39G8B.1 gene9064 1663 1461 1478 4189 4024 4402 83.059387589 67.101146028 69.118782907 221.85994234 195.94901 209.53104804 5.64478915775807e-14 1.44719906707298 up [R] General function prediction only -- K00011|0|cel:CELE_Y39G8B.1|Y39G8B.1; Protein Y39G8B.1, isoform A; K00011 aldehyde reductase [EC:1.1.1.21] (A) Pentose and glucuronate interconversions (ko00040);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Glycerolipid metabolism (ko00561) [R] General function prediction only Aldo/keto reductase family Protein Y39G8B.1, isoform b {ECO:0000313|EMBL:CAB60335.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein Y39G8B.1, isoform b [Caenorhabditis elegans] F14F9.4 gene34455 2746 3242 3186 789 817 671 46.8544 55.1942 53.6813 13.45577 13.95497 11.30824 5.3139094081347e-25 -2.01804534200126 down -- -- -- -- -- -- -- -- Protein F14F9.4 {ECO:0000313|EMBL:CCD62732.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F14F9.4 [Caenorhabditis elegans] clec-47 gene38579 1475 2130 641 84 121 165 457.662 600.099 184.089 27.0436 35.0341 51.3296 0.00144150692831588 -3.52695411614349 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-47 {ECO:0000313|EMBL:CAB05809.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein CLEC-47 [Caenorhabditis elegans] asp-12 gene35654 149 172 172 57 45 45 6.433318067 7.63247 7.50981 2.521507 1.95781773 2.07602 1.03899130997507e-07 -1.75390153676331 down -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal Protein ASP-12 {ECO:0000313|EMBL:CCD64748.1} OS=Caenorhabditis elegans PE=3 SV=1 S Function unknown Protein ASP-12 [Caenorhabditis elegans] W02B12.4 gene8337 247 261 232 115 106 101 8.3237240272906 9.23657255530077 8.10868200055647 4.18926761170305 3.88642855638538 3.51439720037 6.84129916115695e-05 -1.20848719490601 down [I] Lipid transport and metabolism -- -- -- [R] General function prediction only Carboxylesterase family Protein W02B12.4 {ECO:0000313|EMBL:CAA91397.3} OS=Caenorhabditis elegans PE=4 SV=3 I Lipid transport and metabolism Protein W02B12.4 [Caenorhabditis elegans] F22F7.2 gene33465 2505 2754 2512 7519 7283 7803 91.991004225 96.487714666 91.244140982 276.788302086 262.645495502 280.201517171 1.23230861690507e-15 1.53305394505091 up [S] Function unknown Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [S] Function unknown Saccharopine dehydrogenase Protein F22F7.2 {ECO:0000313|EMBL:CCD67441.1} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein F22F7.2 [Caenorhabditis elegans] C32H11.3 gene20309 118 87 64 38 32 36 7.791158 5.529073 4.173815 2.561938 2.143207 2.413359 0.00424309835630232 -1.35238104301622 down -- -- -- -- -- -- -- CUB-like domain Protein C32H11.3 {ECO:0000313|EMBL:CAB05130.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C32H11.3 [Caenorhabditis elegans] srj-38 gene33157 51 52 29 102 135 135 2.76343434279 2.691840898091 1.51991234858 5.606548 7.2718 7.43414 2.92881426172124e-05 1.48737290056651 up -- -- -- K08473|0|cel:CELE_T02B11.5|srj-38; Protein SRJ-38; K08473 nematode chemoreceptor (A) -- -- -- Serpentine type 7TM GPCR chemoreceptor Srj;; Serpentine type 7TM GPCR chemoreceptor Str;; Serpentine type 7TM GPCR chemoreceptor Srd;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Sri Protein SRJ-57 {ECO:0000313|EMBL:CCD71819.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein SRJ-38 [Caenorhabditis elegans] Y45G12B.3 gene33648 672 648 640 1696 1701 1741 24.6242010139969 22.7680004871806 23.3124000001413 63.81492979 60.67796 62.4984124900023 2.49509460547858e-11 1.38284372801368 up [R] General function prediction only Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00109|0|cel:CELE_Y45G12B.3|Y45G12B.3; Protein Y45G12B.3; K00109 2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] (A) Butanoate metabolism (ko00650) [S] Function unknown FAD dependent oxidoreductase Putative uncharacterized protein {ECO:0000313|EMBL:EGT30836.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y45G12B.3 [Caenorhabditis elegans] fil-1 gene38493 151 160 148 46 81 90 12.063 12.8153 11.8184 3.79044 6.52964 7.20691 0.00163103529946489 -1.08626471082213 down -- -- Molecular Function: hydrolase activity (GO:0016787);; -- -- -- -- Lipase (class 2) Protein FIL-1 {ECO:0000313|EMBL:CAB01664.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein FIL-1 [Caenorhabditis elegans] clec-186 gene20286 1450 1932 1548 796 719 675 76.11063 96.9451 77.38875 39.93781 35.74857 34.19382 2.03191450813892e-08 -1.17857784054575 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-186 {ECO:0000313|EMBL:CAB05324.2} OS=Caenorhabditis elegans PE=4 SV=2 G Carbohydrate transport and metabolism Protein CLEC-186 [Caenorhabditis elegans] F21D5.3 gene18660 692 843 652 2044 1903 2091 21.5920257210113 23.583893869 19.493013441 53.04907270779 51.77571056655 52.2781613895 7.22213250592977e-13 1.45753629009224 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Multicopper oxidase;; Multicopper oxidase;; Multicopper oxidase Protein F21D5.3, isoform a {ECO:0000313|EMBL:CAA91039.2} OS=Caenorhabditis elegans PE=4 SV=2 BD Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning Protein F21D5.3, isoform a [Caenorhabditis elegans] ugt-8 gene34376 1963 2064 1701 439 337 322 56.56948 54.826333 46.84858 11.77206 9.44423 8.2321 8.85201183974226e-31 -2.3919880763117 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-8 {ECO:0000313|EMBL:CCD62608.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein UGT-8 [Caenorhabditis elegans] T22C1.8 gene1999 107 142 186 74 62 76 3.04551 4.06387 5.33941 2.15182 1.7817 2.19876 0.00850462883141984 -1.0435909872604 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein T22C1.8 {ECO:0000313|EMBL:CAA99930.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein T22C1.8 [Caenorhabditis elegans] grl-20 gene13686 10537 9565 3848 486 1438 919 1302.15784000012 1067.42911 492.369408301 63.5505910169 195.902906738 111.260223713 0.000594814176305848 -3.08133544802459 down -- -- -- -- -- -- -- Ground-like domain Protein GRL-20 {ECO:0000313|EMBL:CCD65348.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GRL-20 [Caenorhabditis elegans] fbxa-127 gene39309 291 384 342 104 104 241 10.8331009737897 13.632295218744 12.0409427396768 4.63165442564655 4.29324609313108 8.75509708691457 0.00248885792900926 -1.18431455306384 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-127 {ECO:0000313|EMBL:CAD89750.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein FBXA-127 [Caenorhabditis elegans] B0393.4 gene10591 142 169 193 80 83 83 3.308647 3.91439 4.440789 1.891424 1.944985 1.93207 0.00211538884742014 -1.04160992502655 down -- -- Biological Process: regulation of gene silencing by miRNA (GO:0060964);; -- -- -- -- piRNA pathway germ-plasm component Protein B0393.4 {ECO:0000313|EMBL:CAA86057.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein B0393.4 [Caenorhabditis elegans] W08E12.2 gene13966 44 58 97 213 333 278 33.3997 39.71 70.9147 187.212 236.83 218.838 1.2253454316864e-07 2.04476975069747 up -- -- -- -- -- -- -- -- Protein W08E12.2 {ECO:0000313|EMBL:CCD74010.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein W08E12.2 [Caenorhabditis elegans] pgp-5 gene44477 9026 12707 10168 2025 2381 2048 153.934160038006 221.683169712051 174.929805864105 35.2651380650338 41.3863183000055 35.7091627076 4.82089133539533e-17 -2.31245720809061 down [V] Defense mechanisms Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; K05660|0|cel:CELE_C05A9.1|pgp-5; Protein PGP-5, isoform B; K05660 ATP-binding cassette, subfamily B (MDR/TAP), member 5 (A) ABC transporters (ko02010) [Q] Secondary metabolites biosynthesis, transport and catabolism ABC transporter;; ABC transporter transmembrane region;; RecF/RecN/SMC N terminal domain;; AAA domain;; AAA ATPase domain;; AAA domain;; AAA domain;; Protein of unknown function, DUF258;; P-loop containing region of AAA domain;; AAA domain;; ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; Molybdopterin guanine dinucleotide synthesis protein B;; Predicted ATPase of the ABC class Protein PGP-5, isoform a {ECO:0000313|EMBL:CAA94202.2} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein PGP-5, isoform a [Caenorhabditis elegans] ugt-47 gene36347 407 536 427 974 993 808 16.767948 21.71509 17.328398 39.60786 40.16032 33.52946 1.39466435129321e-05 1.01044043065467 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 CBN-UGT-47 protein {ECO:0000313|EMBL:EGT42702.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein UGT-47 [Caenorhabditis elegans] C13A2.1 gene35267 337 374 161 45 82 43 9.77595 12.31332 5.04631 1.2731308 2.99239 1.227851459 0.0009978504817088 -2.36681625649692 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C13A2.1 {ECO:0000313|EMBL:CCD63108.2} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown Protein C13A2.1 [Caenorhabditis elegans] C13A2.6 gene35260 272 240 99 3 30 10 10.59 9.2535 4.13756 0.1456614053 1.1589858819 0.451295 7.1132252671037e-05 -3.83470556413783 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein C13A2.6 {ECO:0000313|EMBL:CCD63100.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C13A2.6 [Caenorhabditis elegans] slc-36.5 gene6733 249 231 152 358 595 710 14.2301354968273 13.274825373673 9.0341443971 20.6382074402869 38.51045951 41.4106148399887 0.00964241912090834 1.38959297054411 up -- -- -- -- -- [E] Amino acid transport and metabolism Transmembrane amino acid transporter protein Protein C44B7.6, isoform a {ECO:0000313|EMBL:CCD61559.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein C44B7.6, isoform a [Caenorhabditis elegans] C31B8.12 gene33729 18 23 15 74 94 118 0.985804 1.23252 0.790643 3.85429 4.93657 6.24958 8.00941354855368e-09 2.3461828777305 up -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C31B8.12 {ECO:0000313|EMBL:CCD66303.1} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein C31B8.12 [Caenorhabditis elegans] C02F12.5 gene41809 215 226 240 617 769 739 48.05216 47.41121 52.8214 144.0427 170.5114 172.3413 5.95288106538326e-12 1.63508163921421 up -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT30633.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein C02F12.5 [Caenorhabditis elegans] oac-7 gene39129 247 297 274 59 78 44 8.23559 9.790674 8.90291 2.0031638 2.542613 1.484250671004 1.54759307259868e-13 -2.18381342251936 down -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-7 {ECO:0000313|EMBL:CAB05690.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein OAC-7 [Caenorhabditis elegans] C08E3.1 gene4737 70 59 21 161 312 360 289.3911 208.9573 87.2552 943.063 1357.141 1979.973 0.000469075086359849 2.46659204463288 up -- -- -- -- -- -- -- -- Protein C08E3.13 {ECO:0000313|EMBL:CCD63678.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C08E3.1 [Caenorhabditis elegans] gst-23 gene33852 39 23 22 63 68 69 5.67244 3.21095 3.1775 9.39649 9.65285 10.0505 0.00372762582136055 1.24329335098456 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-23 {ECO:0000313|EMBL:CCD70568.1} OS=Caenorhabditis elegans PE=1 SV=1 S Function unknown Protein GST-23 [Caenorhabditis elegans] C13A2.9 gene35257 1028 882 423 25 121 47 81.7249 70.3621 33.6638 2.06465 9.69612 3.85592 1.25866016329022e-05 -3.6020791998608 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C13A2.9 {ECO:0000313|EMBL:CCD63101.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C13A2.9 [Caenorhabditis elegans] hpo-15 gene34571 3646 4341 3390 1771 1807 1927 121.8295 145.742 112.098 60.2917 60.3859 63.69 9.80692446137648e-08 -1.05466370538472 down -- -- Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [H] Coenzyme transport and metabolism Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain Protein HPO-15 {ECO:0000313|EMBL:CCD65133.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein HPO-15 [Caenorhabditis elegans] F07G11.1 gene35274 643 549 261 22 74 18 48.8469536479001 41.810823 19.7949408928 1.903109843 5.64900729900001 1.42621725274 1.30570725600925e-05 -3.67981994896995 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F07G11.1 {ECO:0000313|EMBL:CCD64329.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein F07G11.1 [Caenorhabditis elegans] C05D12.2 gene8320 285 388 325 2318 2900 4091 4.6442181 6.3470765178 5.197926715 37.242805324 46.99320927 66.545510968 2.88762674113628e-09 3.21593258585442 up -- -- -- -- -- -- -- -- Protein C05D12.2 {ECO:0000313|EMBL:CAA90754.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C05D12.2 [Caenorhabditis elegans] dod-24 gene20320 32926 37669 20837 5228 3779 1404 1966.63 2157.08 1188.48 307.694 217.043 81.5248 2.66838369068472e-09 -3.14608126570552 down -- -- -- -- -- -- -- CUB-like domain Protein DOD-24 {ECO:0000313|EMBL:CAB05138.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein DOD-24 [Caenorhabditis elegans] K11G9.2 gene35021 97 95 78 163 169 215 4.04489 3.97876 3.286699 7.00116 7.1469 9.05109 0.00246862781657284 1.01151755337802 up [I] Lipid transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; -- -- [R] General function prediction only Carboxylesterase family;; alpha/beta hydrolase fold Protein K11G9.2 {ECO:0000313|EMBL:CCD72925.2} OS=Caenorhabditis elegans PE=3 SV=3 R General function prediction only Protein K11G9.2 [Caenorhabditis elegans] Y39B6A.29 gene40143 139 134 71 12 11 14 6.772113044 6.4801743024 3.5719283544 0.600659938316717 0.5343317132864 0.7296880037 4.97974171183741e-07 -3.22495490798806 down -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [S] Function unknown Ion channel regulatory protein UNC-93 Protein Y39B6A.29, isoform a {ECO:0000313|EMBL:CAC51051.2} OS=Caenorhabditis elegans PE=4 SV=2 U Intracellular trafficking, secretion, and vesicular transport Protein Y39B6A.29, isoform a [Caenorhabditis elegans] clec-85 gene13870 2961 3962 2671 978 987 662 257.25120504 331.291210298 223.915191967 86.238604076 82.69825041 56.816230362 1.35788349817235e-08 -1.87730894746914 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-85, isoform a {ECO:0000313|EMBL:CCD83493.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-85 [Caenorhabditis elegans] gpd-3 gene41618 22275 19706 19698 49462 47910 50222 653.637507 582.05812 619.326385 1473.514008 1437.597896 1465.906471 8.54200557647906e-09 1.25107957465884 up [G] Carbohydrate transport and metabolism Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620);; Biological Process: oxidation-reduction process (GO:0055114);; K00134|0|cel:CELE_K10B3.7|gpd-3; Protein GPD-3; K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] (A) Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [G] Carbohydrate transport and metabolism Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain;; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361160} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 R General function prediction only Protein GPD-3 [Caenorhabditis elegans] col-60 gene1761 1105 1155 1230 536 399 354 73.21463 75.1965 81.05351 35.78754 26.26912 23.75452249 3.44955898731503e-11 -1.44570985350415 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-60 {ECO:0000313|EMBL:CAA95812.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein COL-60 [Caenorhabditis elegans] tag-10 gene8956 408 360 337 1580 1618 1464 15.196511905 13.0720674731078 12.5521455992315 59.82687052 58.9487369 53.1311259000005 8.9018049041866e-23 2.06889436221445 up [U] Intracellular trafficking, secretion, and vesicular transport -- -- -- -- -- WD40-like Beta Propeller Repeat Protein TAG-10, isoform a {ECO:0000313|EMBL:CAB05698.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein TAG-10, isoform a [Caenorhabditis elegans] abhd-3.2 gene40960 153 194 180 738 642 483 10.62981 13.08275 10.886978918 48.93817 41.90748 31.31778 2.16300359384341e-09 1.81328831528554 up [R] General function prediction only -- K13696|0|cbr:CBG08080|Hypothetical protein CBG08080; K13696 abhydrolase domain-containing protein 1/3 (A) -- [R] General function prediction only Alpha/beta hydrolase family Putative uncharacterized protein {ECO:0000313|EMBL:EGT54838.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 G Carbohydrate transport and metabolism Protein C44C1.5, isoform a [Caenorhabditis elegans] pitr-4 gene36179 76 88 45 17 11 17 3.28088 3.83852 1.97116 0.745953 0.4842 0.758556 8.06134007129303e-05 -2.22410981945827 down [P] Inorganic ion transport and metabolism Molecular Function: inorganic phosphate transmembrane transporter activity (GO:0005315);; Biological Process: phosphate ion transport (GO:0006817);; Cellular Component: membrane (GO:0016020);; -- -- [P] Inorganic ion transport and metabolism Phosphate transporter family Protein PITR-4 {ECO:0000313|EMBL:CAB11776.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein PITR-4 [Caenorhabditis elegans] irg-1 gene33960 991 1259 965 180 226 168 85.36964 105.64289 81.43069 15.019951 17.410351 14.3372400000012 3.57190116867559e-24 -2.49317374197335 down -- -- -- -- -- -- -- Domain of unknown function (DUF1768) Protein IRG-1 {ECO:0000313|EMBL:CCD62487.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein IRG-1 [Caenorhabditis elegans] Y58A7A.3 gene34437 2177 2533 3050 981 882 777 42.5428886036 50.5712117736014 60.2058826436731 19.5021485352669 17.4901705927591 15.4754232011 4.08300758961146e-11 -1.56315960805914 down -- -- -- -- -- -- -- -- Protein Y58A7A.3 {ECO:0000313|EMBL:CCD63022.1} OS=Caenorhabditis elegans PE=4 SV=1 C Energy production and conversion Protein Y58A7A.3 [Caenorhabditis elegans] F43H9.4 gene35562 1808 1951 1561 483 615 585 144.1651 155.6084 123.785 38.30763 48.883 46.6201 5.07522375354146e-16 -1.66742232264313 down -- -- -- -- -- -- -- -- Protein F43H9.4 {ECO:0000313|EMBL:CCD71176.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein F43H9.4 [Caenorhabditis elegans] gst-25 gene262 47 46 34 123 99 110 6.00176 5.58424 4.30007 15.9622 12.0804 13.6999 0.000183318665067913 1.37782574571289 up -- -- -- K00799|2.2403e-104|cbr:CBG06825|Cbr-gst-1; C. briggsae CBR-GST-1 protein; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein GST-25 {ECO:0000313|EMBL:CCD70778.1} OS=Caenorhabditis elegans PE=3 SV=1 U Intracellular trafficking, secretion, and vesicular transport GST-25 [Caenorhabditis elegans] F35E12.9 gene38006 1254 1436 1186 692 592 609 51.9449400000242 59.0686000001272 49.006674 28.8689900133458 23.9429417328 25.1686607557865 2.15020340385511e-06 -1.04196908579516 down -- -- -- -- -- -- -- CUB-like domain Protein F35E12.9, isoform b {ECO:0000313|EMBL:CAI91173.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F35E12.9, isoform b [Caenorhabditis elegans] ugt-28 gene1007 439 451 499 219 218 192 17.68298 18.77018 20.73098 9.26979 9.206049 8.066767 1.24798262201633e-05 -1.15054039446684 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-28 {ECO:0000313|EMBL:CCD64216.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein UGT-28 [Caenorhabditis elegans] ZK84.1 gene6360 4502 3729 2932 1732 1779 1521 65.272697595 52.46037035 41.112022289 24.84655221 24.7359733295 21.065704 0.000101779374738146 -1.15805483486143 down -- -- -- -- -- -- -- -- Protein ZK84.1 {ECO:0000313|EMBL:CCD73326.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein ZK84.1 [Caenorhabditis elegans] gst-4 gene19246 4194 3692 3507 17659 14559 15644 277.131030284 227.492200000002 226.618000000071 1372.550799 1083.21444 1178.86012 2.37280238045292e-26 2.06240917987797 up [O] Posttranslational modification, protein turnover, chaperones Molecular Function: protein binding (GO:0005515);; K00799|6.36308e-150|cel:CELE_K08F4.7|gst-4; Protein GST-4; K00799 glutathione S-transferase [EC:2.5.1.18] (A) Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982) [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain Protein CBR-GST-4 {ECO:0000313|EMBL:CAP24347.1} OS=Caenorhabditis briggsae PE=3 SV=1 S Function unknown Protein GST-4 [Caenorhabditis elegans] cth-1 gene39024 223 193 223 2215 2956 2281 11.0988786850164 9.54064089900071 11.2959927 85.81987008 123.213810000027 91.432625 2.59386559106539e-32 3.53657535321492 up [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K01758|0|cel:CELE_F22B8.6|cth-1; Protein CTH-1, isoform B; K01758 cystathionine gamma-lyase [EC:4.4.1.1] (A) Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Selenocompound metabolism (ko00450);; Biosynthesis of amino acids (ko01230) [E] Amino acid transport and metabolism Cys/Met metabolism PLP-dependent enzyme;; Aminotransferase class I and II;; Methionine gamma-lyase;; DegT/DnrJ/EryC1/StrS aminotransferase family;; Aminotransferase class-V Protein CTH-1, isoform a {ECO:0000313|EMBL:CAB05492.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein CTH-1, isoform a [Caenorhabditis elegans] irg-4 gene20169 13352 18326 8129 241 174 48 929.649 1269.485 556.4788 16.97625 12.15328 3.40924 2.30440395162856e-13 -6.43775474222183 down -- -- -- -- -- -- -- CUB-like domain Protein F08G5.6 {ECO:0000313|EMBL:CAA94586.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F08G5.6 [Caenorhabditis elegans] Y38A10A.2 gene34790 283 325 161 94 103 80 9.52227 10.9819 5.37822 3.2069 3.4871 2.75417 0.0052940437743461 -1.48171138710818 down -- -- -- -- -- -- -- Protein of unknown function (DUF229) Protein Y38A10A.2 {ECO:0000313|EMBL:CCD69633.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y38A10A.2 [Caenorhabditis elegans] nhr-237 gene33315 129 169 100 76 65 49 8.488063 10.9819595120464 6.47519084840149 4.99705728 4.21179083200005 3.208272359 0.00857891197331695 -1.07592023600982 down -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-237 {ECO:0000313|EMBL:CCD69586.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein NHR-237 [Caenorhabditis elegans] T10B5.8 gene33384 145 164 155 85 95 47 6.37915 6.93472 6.624422 3.791718 4.247159 1.83593 0.00271267131564331 -1.04003973653979 down [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein T10B5.8 {ECO:0000313|EMBL:CCD74228.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T10B5.8 [Caenorhabditis elegans] H20J04.1 gene5715 77 80 96 38 30 40 1.74262 1.84538 2.17938 0.895036 0.708339 0.942865 0.00201213391713479 -1.23527193650244 down -- -- -- -- -- -- -- Domain of unknown function Protein H20J04.1 {ECO:0000313|EMBL:CCD61676.1} OS=Caenorhabditis elegans PE=4 SV=1 B Chromatin structure and dynamics Protein H20J04.1 [Caenorhabditis elegans] smf-2 gene42988 72 62 80 23 18 34 3.31847 2.87278 3.69989 1.12018 0.867847 1.63514 0.000240096234053617 -1.51896611678968 down [P] Inorganic ion transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K12347|0|cel:CELE_K11G12.3|smf-2; Protein SMF-2; K12347 natural resistance-associated macrophage protein (A) Lysosome (ko04142) [P] Inorganic ion transport and metabolism Natural resistance-associated macrophage protein Protein SMF-2 {ECO:0000313|EMBL:CCD70795.2} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein SMF-2 [Caenorhabditis elegans] Y17D7B.3 gene40084 29 31 36 5 6 9 2.93261 3.01565 3.44187 0.551909 0.618468 0.939868 2.42942241815434e-05 -2.26841871502647 down -- -- -- -- -- -- -- -- Protein Y17D7B.3 {ECO:0000313|EMBL:CAA16300.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y17D7B.3 [Caenorhabditis elegans] Y4C6B.4 gene15341 132 142 126 262 339 485 5.49521000048972 6.31650297209 4.7489212899 11.07715 13.3447809 19.5257 0.00366844635697994 1.4352208377982 up [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein Y4C6B.4, isoform a {ECO:0000313|EMBL:CCD71125.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein Y4C6B.4, isoform a [Caenorhabditis elegans] aman-3 gene1161 383 447 321 709 705 1073 6.92438 8.26479 5.82347 13.0822 13.0134 19.92 0.0045686512927976 1.10492535656834 up [G] Carbohydrate transport and metabolism Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 38 N-terminal domain;; Glycosyl hydrolases family 38 C-terminal domain;; Alpha mannosidase, middle domain Alpha-mannosidase {ECO:0000256|RuleBase:RU361199} OS=Caenorhabditis elegans PE=3 SV=2 G Carbohydrate transport and metabolism Protein AMAN-3 [Caenorhabditis elegans] C10G8.3 gene34506 163 124 79 22 32 29 23.15074 16.08991 9.31325 3.648812 4.506627 3.695667 0.000379620197687417 -2.14833723970757 down -- -- Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; -- -- [O] Posttranslational modification, protein turnover, chaperones Kunitz/Bovine pancreatic trypsin inhibitor domain Protein C10G8.3 {ECO:0000313|EMBL:CCD64158.1} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein C10G8.3 [Caenorhabditis elegans] col-174 gene43314 1472 1209 576 241 334 240 51.6864 38.9538000048692 20.0502 7.39162602436063 9.65501268660009 7.61774500045768 0.00811017087350452 -2.00728011906276 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-174 {ECO:0000313|EMBL:CCD71292.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein COL-174 [Caenorhabditis elegans] F14F9.3 gene34457 268 289 289 124 125 58 5.43669147 5.7326158758 5.95299101 2.44540438863 2.64038965 1.1636646877 3.96120405860799e-07 -1.47150476715512 down -- -- -- -- -- -- -- -- Protein F14F9.3 {ECO:0000313|EMBL:CCD62731.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F14F9.3 [Caenorhabditis elegans] fbxa-15 gene9710 512 613 482 205 209 239 26.17694835905 33.131048914 24.487285 12.024031265 12.7974250275918 13.919509935 2.26575871100025e-07 -1.30636396774074 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-15 {ECO:0000313|EMBL:CCD73896.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-15 [Caenorhabditis elegans] T05H10.3 gene7159 5009 4494 2522 853 1322 878 1437.06 1181.45 683.649 254.144 357.635 249.591 0.000354720112257854 -1.98581104117394 down -- -- -- -- -- [G] Carbohydrate transport and metabolism -- Protein CBG13422 {ECO:0000313|EMBL:CAP32197.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein T05H10.3 [Caenorhabditis elegans] F25A2.1 gene33219 315 331 289 89 82 75 30.21 29.2235 25.8963 8.49447 7.39819 6.86125 9.66679155391957e-12 -1.93447846010405 down -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein F25A2.1 {ECO:0000313|EMBL:CCD69965.1} OS=Caenorhabditis elegans PE=4 SV=3 I Lipid transport and metabolism Protein F25A2.1 [Caenorhabditis elegans] Y87G2A.16 gene3821 406 494 252 42 59 47 19.27982 23.0958 12.14386 2.071273 3.063625 2.45908 3.81683248731564e-07 -2.9680557505994 down -- -- Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [MW] Cell wall/membrane/envelope biogenesis;; Extracellular structures Sulfotransferase family Protein Y87G2A.16 {ECO:0000313|EMBL:CAD92405.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y87G2A.16 [Caenorhabditis elegans] C16D9.1 gene35648 378 368 230 709 810 648 19.59698 18.87359 11.68547 36.24928 41.77923 33.66777 1.93296411512692e-06 1.14237644299258 up -- -- -- -- -- -- -- PAN domain Protein C16D9.1 {ECO:0000313|EMBL:CCD64736.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C16D9.1 [Caenorhabditis elegans] F26A3.4 gene1917 5345 4612 5964 983 888 2236 320.204806 243.1956356274 315.4941682846 50.86773198196 46.3242087398 117.3945373318 4.96725551101308e-12 -1.95969641197577 down [T] Signal transduction mechanisms Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; -- -- [V] Defense mechanisms Dual specificity phosphatase, catalytic domain Protein F26A3.4 {ECO:0000313|EMBL:CAB01700.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein F26A3.4 [Caenorhabditis elegans] ugt-1 gene36480 342 350 207 166 124 97 13.49324828445 14.00011274378 8.22240497258 6.73653914427 4.9303064 3.8803072276 0.00483992880678338 -1.22597283266459 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1 Protein UGT-1 {ECO:0000313|EMBL:CAA94870.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein UGT-1 [Caenorhabditis elegans] oac-24 gene34312 312 287 143 21 62 26 11.1071 10.3396 5.04966 0.787422 2.23376 0.945498 8.96685604084909e-05 -2.77436590044134 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-24 {ECO:0000313|EMBL:CCD65246.2} OS=Caenorhabditis elegans PE=4 SV=3 O Posttranslational modification, protein turnover, chaperones Protein OAC-24 [Caenorhabditis elegans] aagr-2 gene5885 3311 3065 2534 11619 12666 16391 60.941497 57.0955 46.6623 216.4019 234.9373 302.2875 2.45431183472503e-13 2.18374655464516 up [G] Carbohydrate transport and metabolism Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; -- -- [G] Carbohydrate transport and metabolism Glycosyl hydrolases family 31;; Trefoil (P-type) domain Protein AAGR-2 {ECO:0000313|EMBL:CCD69278.1} OS=Caenorhabditis elegans PE=1 SV=3 G Carbohydrate transport and metabolism Protein AAGR-2 [Caenorhabditis elegans] lys-4 gene19808 80 81 107 1609 1885 2412 12.5139 12.2967 16.245 250.953 286.757 375.085 1.27685977403229e-26 4.45610882303964 up -- -- Molecular Function: lysozyme activity (GO:0003796);; Biological Process: peptidoglycan catabolic process (GO:0009253);; Biological Process: cell wall macromolecule catabolic process (GO:0016998);; -- -- -- -- Glycosyl hydrolases family 25 Protein LYS-4 {ECO:0000313|EMBL:CAA97797.1} OS=Caenorhabditis elegans PE=4 SV=1 Z Cytoskeleton Protein LYS-4 [Caenorhabditis elegans] nep-9 gene5411 28 26 40 4 11 15 0.817801 0.745498 1.145 0.137162 0.321172 0.446659 0.00192034624705221 -1.65097994697545 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; -- -- [E] Amino acid transport and metabolism Peptidase family M13;; Peptidase family M13 Protein NEP-9 {ECO:0000313|EMBL:CCD64731.1} OS=Caenorhabditis elegans PE=4 SV=3 E Amino acid transport and metabolism Protein NEP-9 [Caenorhabditis elegans] K02H11.4 gene33290 28 34 38 12 12 9 1.005129 1.271506 1.388254 0.412561680903 0.435622 0.3743469 0.00211508422693807 -1.60717248421162 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein K02H11.4 {ECO:0000313|EMBL:CCD67033.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K02H11.4 [Caenorhabditis elegans] F25E5.8 gene35333 1296 1206 1641 2814 3389 3652 95.34659425 87.0979580000156 120.222862976133 206.434961800257 243.48641643 264.574387651123 5.38949643524742e-10 1.24394272118018 up -- -- -- -- -- -- -- -- Protein F25E5.8, isoform a {ECO:0000313|EMBL:CCD65093.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F25E5.8, isoform a [Caenorhabditis elegans] F58G6.3 gene19017 150 172 167 858 647 422 13.2714 13.29603 14.564984 62.78565 49.6189 29.51548 0.000341203426813355 1.96902189734627 up -- -- Molecular Function: copper ion transmembrane transporter activity (GO:0005375);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: copper ion transmembrane transport (GO:0035434);; -- -- [P] Inorganic ion transport and metabolism Ctr copper transporter family Protein F58G6.3 {ECO:0000313|EMBL:CAA92470.2} OS=Caenorhabditis elegans PE=4 SV=2 P Inorganic ion transport and metabolism Protein F58G6.3 [Caenorhabditis elegans] sams-1 gene44869 5408 6199 4485 12976 11150 10669 130.2955 137.0081 104.9875 298.1183 262.2419 243.3949 2.85688680425244e-08 1.10408000587605 up [H] Coenzyme transport and metabolism Molecular Function: methionine adenosyltransferase activity (GO:0004478);; Biological Process: S-adenosylmethionine biosynthetic process (GO:0006556);; K00789|0|cel:CELE_C49F5.1|sams-1; Protein SAMS-1; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A) Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230) [H] Coenzyme transport and metabolism S-adenosylmethionine synthetase, C-terminal domain;; S-adenosylmethionine synthetase, central domain;; S-adenosylmethionine synthetase, N-terminal domain S-adenosylmethionine synthase {ECO:0000256|RuleBase:RU000541} OS=Caenorhabditis japonica PE=3 SV=1 BK Chromatin structure and dynamics;; Transcription Protein SAMS-1 [Caenorhabditis elegans] lipl-4 gene34978 87 66 36 113 161 156 5.2247550748 4.087452 2.1460005421 6.810945925 9.5148015855 9.3700183355 0.00187580476417599 1.17816978934773 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 I Lipid transport and metabolism Protein LIPL-4 [Caenorhabditis elegans] C49G7.13 gene34131 43 36 54 8 9 5 3.10016 2.58111 3.80136 0.611744 0.661005 0.415587 1.31215945677994e-07 -2.60390765743449 down -- -- -- -- -- -- -- CUB-like domain Protein C49G7.7 {ECO:0000313|EMBL:CCD67694.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C49G7.7 [Caenorhabditis elegans] K09C6.9 gene33147 240 173 233 38 19 49 38.9786 26.8177 36.6124 6.4139 3.04279 7.89685 2.45105831533084e-16 -2.61468968628022 down -- -- -- -- -- -- -- -- Protein K09C6.9 {ECO:0000313|EMBL:CCD71079.1} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein K09C6.9 [Caenorhabditis elegans] C12D5.9 gene35437 74 73 70 25 7 18 5.03315 5.11607 4.8498 1.77064 0.514052 1.27374 2.85192613175592e-07 -2.1273862042383 down -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein C12D5.9 {ECO:0000313|EMBL:CCD64277.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein C12D5.9 [Caenorhabditis elegans] C08F11.1 gene20614 286 327 223 713 769 922 43.4433 47.2401 32.4474 108.282 111.685 138.152 6.20942345437981e-11 1.51674919343408 up -- -- -- -- -- -- -- -- Protein C08F11.1 {ECO:0000313|EMBL:CAB62780.2} OS=Caenorhabditis elegans PE=4 SV=2 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C08F11.1 [Caenorhabditis elegans] T05E12.6 gene39448 267 378 289 817 871 1105 12.2900700805276 17.091215244 13.00592 36.819448501 40.64709 50.0664121 8.05434071414778e-10 1.57384027453383 up -- -- -- -- -- -- -- CUB-like domain Protein T05E12.6, isoform a {ECO:0000313|EMBL:CAB04684.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein T05E12.6, isoform a [Caenorhabditis elegans] acs-2 gene38765 1825 1306 2674 27542 33802 41200 170.7980559245 150.089222699582 251.9854605 672.941393579 807.040141897 977.3921408 3.44918976772618e-26 4.13726986045336 up [IQ] Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; K01897|0|cel:CELE_F28F8.2|acs-2; Protein ACS-2; K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A) Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; Peroxisome (ko04146) [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Protein ACS-2 {ECO:0000313|EMBL:CAB03012.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein ACS-2 [Caenorhabditis elegans] C30F2.4 gene46300 309 342 197 100 101 100 320.740566671 345.031016227 182.507818658 71.0802140046392 59.7448243737875 63.6864825268 0.000224009034244463 -1.50245499587547 down -- -- -- -- -- -- -- -- Protein C30F2.4 {ECO:0000313|EMBL:CAE17702.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C30F2.4 [Caenorhabditis elegans] pfk-1.2 gene36133 106 122 138 50 57 71 2.71597 3.20453 3.65091 1.33301 1.5141 1.88025 0.00453284288120845 -1.04596018164352 down [G] Carbohydrate transport and metabolism Molecular Function: 6-phosphofructokinase activity (GO:0003872);; Biological Process: glycolytic process (GO:0006096);; K00850|0|cel:CELE_C50F4.2|pfk-2; Protein PFK-2; K00850 6-phosphofructokinase 1 [EC:2.7.1.11] (A) Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018) [G] Carbohydrate transport and metabolism Phosphofructokinase Protein CBG19122 {ECO:0000313|EMBL:CAP36423.2} OS=Caenorhabditis briggsae PE=3 SV=2 R General function prediction only Protein PFK-2 [Caenorhabditis elegans] F55C10.4 gene36983 22 22 23 6 3 10 0.881449 0.866937 0.892755 0.255039 0.143547 0.415528 0.00234684339039582 -1.82432122423642 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Putative uncharacterized protein {ECO:0000313|EMBL:EFP06804.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein F55C10.4 [Caenorhabditis elegans] K07H8.5 gene18505 51 69 66 21 29 34 2.442196 3.48651 3.27557 0.9986611 1.346730656 1.5688828086 0.00908178726806788 -1.15241580647552 down -- -- -- -- -- -- -- -- Protein K07H8.5 {ECO:0000313|EMBL:CCD70611.1} OS=Caenorhabditis elegans PE=4 SV=2 MW Cell wall/membrane/envelope biogenesis;; Extracellular structures Protein K07H8.5 [Caenorhabditis elegans] acox-1.1 gene3646 1425 1397 1291 3373 3092 3255 29.2285354715 28.089244611 24.7804473811295 64.9839256403 61.7738850948992 66.8556803890001 3.45636093091703e-10 1.23292532293726 up [I] Lipid transport and metabolism Molecular Function: acyl-CoA oxidase activity (GO:0003997);; Cellular Component: peroxisome (GO:0005777);; Biological Process: fatty acid beta-oxidation (GO:0006635);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; K00232|0|cbr:CBG07943|Hypothetical protein CBG07943; K00232 acyl-CoA oxidase [EC:1.3.3.6] (A) Fatty acid degradation (ko00071);; alpha-Linolenic acid metabolism (ko00592);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; Peroxisome (ko04146) [I] Lipid transport and metabolism Acyl-CoA oxidase;; Acyl-coenzyme A oxidase N-terminal;; Acyl-CoA dehydrogenase, middle domain Acyl-coenzyme A oxidase {ECO:0000256|PIRNR:PIRNR000168} OS=Caenorhabditis elegans PE=3 SV=1 I Lipid transport and metabolism Protein ACOX-1, isoform a [Caenorhabditis elegans] nlp-77 gene7060 2144 2311 2146 4903 4851 4494 758.789 753.663 716.798 1856.5 1637.65 1588.74 1.75370215079733e-08 1.10227016816954 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein C06A8.3 {ECO:0000313|EMBL:CCD61461.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein C06A8.3 [Caenorhabditis elegans] papl-1 gene37645 429 424 443 970 1097 1466 20.748440718079 20.7312901174 21.7256418146 47.74508245571 52.8781259941 70.8328110692 7.59774148308312e-06 1.44060835783521 up [R] General function prediction only Molecular Function: acid phosphatase activity (GO:0003993);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; -- -- [G] Carbohydrate transport and metabolism Calcineurin-like phosphoesterase;; Iron/zinc purple acid phosphatase-like protein C Purple acid phosphatase {ECO:0000256|RuleBase:RU361203} OS=Caenorhabditis elegans PE=3 SV=1 D Cell cycle control, cell division, chromosome partitioning Protein F18E2.1, isoform a [Caenorhabditis elegans] F36A2.3 gene2247 925 906 912 2393 2350 2586 52.21616 51.5481 51.760414 136.89999149 133.70500217687 146.5543016 1.48137955462422e-12 1.41053447344685 up [C] Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- -- -- Malate/L-lactate dehydrogenase Protein F36A2.3 {ECO:0000313|EMBL:CAB03073.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F36A2.3 [Caenorhabditis elegans] sri-36 gene5071 572 579 546 309 239 256 68.8106000388105 63.163200018989 60.1041000420165 43.5060700873041 25.9130700029095 26.6564100601885 1.8519107034321e-05 -1.08605896415526 down -- -- -- -- -- -- -- Serpentine type 7TM GPCR chemoreceptor Sri;; Serpentine type 7TM GPCR chemoreceptor Srh;; Serpentine type 7TM GPCR chemoreceptor Srd Protein SRI-36 {ECO:0000313|EMBL:CCD68471.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein SRI-36 [Caenorhabditis elegans] W03D8.5 gene530 21 38 34 16 9 10 1.3737 2.40006 2.27357 1.05142 0.605114 0.690408 0.0087798877768564 -1.41855439046746 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein W03D8.5 [Caenorhabditis elegans] clec-166 gene13518 245 237 176 1984 2357 2625 12.091786 11.14712 8.411472 96.16495 111.91592 125.7155 2.9604617801373e-40 3.39702180922958 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain Protein CLEC-166 {ECO:0000313|EMBL:CCD63950.2} OS=Caenorhabditis elegans PE=4 SV=2 W Extracellular structures CLEC-166 [Caenorhabditis elegans] T02B11.3 gene33151 4842 5033 3149 1554 1591 1669 555.538 549.566 354.643 179.0999 175.4352 188.0467 3.64604930377834e-05 -1.44380817627999 down -- -- -- -- -- -- -- -- Protein T02B11.3, isoform a {ECO:0000313|EMBL:CCD72447.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein T02B11.3, isoform a [Caenorhabditis elegans] F22F7.3 gene33461 48 34 62 106 113 143 1.471035 1.027986 1.939469 3.26542 3.6121 4.37191 0.000252435385155047 1.32377580698062 up -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein F22F7.3 {ECO:0000313|EMBL:CCD67442.2} OS=Caenorhabditis elegans PE=4 SV=3 G Carbohydrate transport and metabolism Protein F22F7.3 [Caenorhabditis elegans] C31H5.1 gene2322 33 28 29 11 8 8 2.63797 2.28442 2.28117 0.916512 0.657008 0.68793 0.00126344677900535 -1.74589021704209 down -- -- -- -- -- -- -- Alpha/beta hydrolase of unknown function (DUF1057);; Alpha/beta hydrolase family;; Alpha/beta hydrolase family Protein C31H5.1 {ECO:0000313|EMBL:CAB07844.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C31H5.1 [Caenorhabditis elegans] C45B2.1 gene42729 374 586 641 168 183 109 689.329 977.364 1127.47 382.626 318.639 220.7 1.77779501283122e-05 -1.80683955033854 down -- -- -- -- -- -- -- -- Protein C45B2.1 {ECO:0000313|EMBL:CCD63809.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein C45B2.1 [Caenorhabditis elegans] T19C9.8 gene39528 200 146 146 738 747 1351 13.2219 9.22363 9.41929 48.5577 48.2729 88.1399 0.000203933630685055 2.5207984087807 up -- -- -- -- -- -- -- -- Protein T19C9.8 {ECO:0000313|EMBL:CAB07486.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein T19C9.8 [Caenorhabditis elegans] F41C3.4 gene5813 1733 1890 2285 6392 6715 9493 173.814173826 153.9588385295 207.702019213 352.222859746 355.9576982482 464.388251947 8.04090096590555e-08 1.929701895793 up -- -- -- -- -- [P] Inorganic ion transport and metabolism Got1/Sft2-like family Putative uncharacterized protein {ECO:0000313|EMBL:EFO91377.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein F41C3.4 [Caenorhabditis elegans] T05E11.8 gene19607 373 372 211 85 125 115 45.4115 42.338 24.7846 10.6272 14.5816 13.9535 0.000822596783719559 -1.56385635890377 down -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein T05E11.8 {ECO:0000313|EMBL:CAA92976.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein T05E11.8 [Caenorhabditis elegans] W01B6.3 gene19209 60 44 21 2 12 6 4.411859 2.308662 0.934042 0.13603399 0.679908000006213 0.38274057358291 0.00711214623765219 -2.65000270930566 down -- -- Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [R] General function prediction only Major Facilitator Superfamily Protein W01B6.3 {ECO:0000313|EMBL:CAA92626.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein W01B6.3 [Caenorhabditis elegans] col-33 gene14275 3053 2351 1033 205 435 370 163.25 117.298 52.5868 10.8351 21.9559 18.8323 0.00400603039597495 -2.67921496542191 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-33 {ECO:0000313|EMBL:CCD69526.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein COL-33 [Caenorhabditis elegans] tkt-1 gene19294 8771 8555 9167 18546 17080 18137 259.0507297 251.108587888571 267.55211208146 553.047911067 501.492806549 530.800972415 8.85877497666007e-07 1.01344471837374 up [G] Carbohydrate transport and metabolism Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; K00615|0|cel:CELE_F01G10.1|tkt-1; Protein TKT-1; K00615 transketolase [EC:2.2.1.1] (A) Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230) [G] Carbohydrate transport and metabolism Transketolase, thiamine diphosphate binding domain;; Transketolase, pyrimidine binding domain;; Transketolase, C-terminal domain;; Dehydrogenase E1 component Protein TKT-1 {ECO:0000313|EMBL:CAB02889.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein TKT-1 [Caenorhabditis elegans] F28A12.3 gene35789 826 829 731 2796 3155 3957 32.6964740242199 31.9363400068369 29.61230649023 117.377800000156 129.1748 163.6045 4.13959374252363e-13 2.0473382001521 up -- -- -- -- -- -- -- Activin types I and II receptor domain Protein F28A12.3 {ECO:0000313|EMBL:CCD70114.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F28A12.3 [Caenorhabditis elegans] oac-20 gene38964 2435 2579 2409 906 652 254 76.4067 80.185 73.9873 28.50763 20.20612 8.09475 1.83951460564936e-24 -2.04520326869646 down -- -- Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- [R] General function prediction only Acyltransferase family Protein OAC-20 {ECO:0000313|EMBL:CAB04331.3} OS=Caenorhabditis elegans PE=4 SV=3 S Function unknown Protein OAC-20 [Caenorhabditis elegans] Y45F10D.2 gene21094 32 44 21 81 72 79 7.37772 8.98615 4.49755 18.2758 15.416 17.4919 0.00230531718006978 1.24983805052758 up -- -- -- -- -- -- -- -- Protein Y45F10D.2 {ECO:0000313|EMBL:CAA16377.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y45F10D.2 [Caenorhabditis elegans] F23B12.1 gene38287 81 90 84 44 20 32 5.73619 6.16219 5.77498 3.16276 1.40275 2.2399 0.000334742756229195 -1.41850426741155 down [T] Signal transduction mechanisms Molecular Function: hydrolase activity (GO:0016787);; -- -- [TR] Signal transduction mechanisms;; General function prediction only Calcineurin-like phosphoesterase Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein F23B12.1 [Caenorhabditis elegans] clec-143 gene7999 85 109 79 10 10 14 5.01951 6.4152 4.6748 0.624437 0.600614 0.858775 2.32496807888362e-13 -3.01194680232459 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain Protein CLEC-143 {ECO:0000313|EMBL:CAA88487.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein CLEC-143 [Caenorhabditis elegans] fbxa-12 gene9925 54 69 43 108 127 139 4.11328439235 5.23554203084411 3.28510496024537 8.34614836988 9.82026520204 10.791383612 0.00130439239969099 1.16483628588502 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain;; F-box-like Protein FBXA-12 {ECO:0000313|EMBL:CCD67051.1} OS=Caenorhabditis elegans PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein FBXA-12 [Caenorhabditis elegans] xtr-2 gene45001 13 16 1 26 35 26 0.5621607878 0.7730479296 0.079774996662 1.13938597153 1.620755 1.1343427 0.00555382560708194 1.52681774609726 up -- -- -- -- -- -- -- -- Protein XTR-2 {ECO:0000313|EMBL:CAA92152.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein XTR-2 [Caenorhabditis elegans] fbxa-24 gene5586 226 228 165 80 95 99 25.7412 25.9619 18.9353 9.08349 10.9002 11.4024 0.000193597974354923 -1.18305702146845 down -- -- -- -- -- -- -- FTH domain Protein FBXA-24 {ECO:0000313|EMBL:CCD64808.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein FBXA-24 [Caenorhabditis elegans] aqp-1 gene6863 263 225 274 2785 3708 4898 25.042148362 21.3615585233 26.203071684 269.9220660672 351.5200844351 467.2240738588 8.64649223633303e-13 3.89623521109919 up [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|0|cel:CELE_F32A5.5|aqp-1; Protein AQP-1, isoform B; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-1, isoform a {ECO:0000313|EMBL:CCD66276.1} OS=Caenorhabditis elegans PE=3 SV=2 O Posttranslational modification, protein turnover, chaperones Protein AQP-1, isoform a [Caenorhabditis elegans] Y57E12B.11 gene35133 99 97 30 0 12 9 875.955 812.366 272.961 0 104.697 105.116 0.00258983690233113 -3.43193431458383 down -- -- -- -- -- -- -- -- Protein Y57E12B.11 {ECO:0000313|EMBL:CDH93307.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Y57E12B.11 [Caenorhabditis elegans] F17B5.4 gene3720 347 247 127 7 42 28 31.30117 22.43319 11.279912 0.683866282000001 3.856156 2.542672 0.000575567076194363 -3.23272229759571 down -- -- Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [MW] Cell wall/membrane/envelope biogenesis;; Extracellular structures Sulfotransferase family Protein F17B5.4 {ECO:0000313|EMBL:CAB02972.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F17B5.4 [Caenorhabditis elegans] nep-4 gene43031 77 97 103 43 46 42 3.738383 4.46189 4.58094 2.142207 2.05946 2.120954 0.00611874304410708 -1.08732841476048 down -- -- Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; -- -- [E] Amino acid transport and metabolism Peptidase family M13 Protein NEP-4 {ECO:0000313|EMBL:CCD67890.1} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein NEP-4 [Caenorhabditis elegans] ugt-21 gene18951 119 128 138 354 310 450 5.09798608672 5.51194613087 5.92784673716 15.47450962297 13.42430964778 19.61110989513 6.54937348429998e-08 1.52616029040414 up [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-21, isoform b {ECO:0000313|EMBL:CDR32712.1} OS=Caenorhabditis elegans PE=3 SV=1 C Energy production and conversion UGT-21, isoform b [Caenorhabditis elegans] msp-50 gene5999 71 92 122 44 36 53 32.5274 37.7011 53.0167 21.9832 15.5432 24.4308 0.0073662366723775 -1.10573223688119 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] cpr-5 gene33206 1470 1019 1375 16469 15558 15325 74.1298 48.4355 67.3356 825.957 744.1823 738.7947 1.65301528369761e-71 3.60737270490738 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_W07B8.5|cpr-5; Protein CPR-5; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein CBR-CPR-5 {ECO:0000313|EMBL:CAP22409.1} OS=Caenorhabditis briggsae PE=3 SV=1 O Posttranslational modification, protein turnover, chaperones Protein CPR-5 [Caenorhabditis elegans] ins-34 gene22075 68 73 144 3 4 2 28.88668 28.6397 59.7724 2.5390434615 1.722671187 1.81060576527 1.64292650820781e-06 -4.99162350465598 down -- -- -- -- -- -- -- -- Protein INS-34 {ECO:0000313|EMBL:CAB05196.2} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein INS-34 [Caenorhabditis elegans] T16H12.9 gene12363 254 257 189 444 550 661 15.707816 15.7852500000003 11.838476166272 27.94424 34.37381 40.87045 3.32599876076238e-05 1.2346606358014 up -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EGT33751.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 S Function unknown Protein T16H12.9 [Caenorhabditis elegans] F08B12.4 gene44666 1732 1903 2011 3494 4199 5786 1322.140525692 1424.9356150644 1454.921994986 3054.560564465 3054.55377440337 4666.8388779 0.00134451727688001 1.24967603826539 up -- -- -- -- -- -- -- -- Protein F08B12.4, isoform a {ECO:0000313|EMBL:CAR97820.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F08B12.4, isoform a [Caenorhabditis elegans] K04A8.21 gene34982 596 596 218 34 80 76 639.8625 557.8998 222.49949 40.65133 78.42357 85.68075 0.00154625254962992 -2.89805633742716 down -- -- -- -- -- -- -- -- Protein SPP-20 {ECO:0000313|EMBL:CCD68858.1} OS=Caenorhabditis elegans PE=4 SV=2 I Lipid transport and metabolism Protein SPP-20 [Caenorhabditis elegans] aat-7 gene4633 11 13 6 52 38 40 0.532223368 0.632492932 0.313191795824 2.44344 1.82143342504 1.93510530082 1.36559028766022e-05 2.10610967560308 up [E] Amino acid transport and metabolism Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; -- -- [E] Amino acid transport and metabolism Amino acid permease;; Amino acid permease Protein AAT-7 {ECO:0000313|EMBL:CCD71779.2} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein AAT-7 [Caenorhabditis elegans] hsp-17 gene35693 610 708 548 1322 1019 1436 130.0276 140.9832 121.424 310.0926 207.9494 323.9024 2.53719811983361e-05 1.00965818175714 up -- -- -- -- -- [O] Posttranslational modification, protein turnover, chaperones Hsp20/alpha crystallin family Protein HSP-17, isoform a {ECO:0000313|EMBL:CCD70808.1} OS=Caenorhabditis elegans PE=3 SV=1 C Energy production and conversion Protein HSP-17, isoform a [Caenorhabditis elegans] C09D4.3 gene1219 119 174 160 71 64 79 5.82719 8.33376 7.67254 3.44343 3.288155 3.86313 0.00167659173978657 -1.08870847385441 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein C09D4.3 {ECO:0000313|EMBL:CCD63888.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C09D4.3 [Caenorhabditis elegans] F46F2.5 gene46041 52 67 22 125 98 128 2.249516 2.83954 0.949972 5.29701 4.15686 5.41043 0.000332152376499209 1.30707310037327 up -- -- -- -- -- -- -- -- Protein F46F2.5 {ECO:0000313|EMBL:CAE17836.3} OS=Caenorhabditis elegans PE=4 SV=3 T Signal transduction mechanisms Protein F46F2.5 [Caenorhabditis elegans] F55G11.2 gene20331 16048 18341 8629 1201 943 97 1130.84766 1269.9264 594.68772 86.74607 67.028088 7.19265541462 3.18439805518119e-09 -4.27536436851542 down -- -- -- -- -- -- -- CUB-like domain Protein F55G11.2 {ECO:0000313|EMBL:CAB05218.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F55G11.2 [Caenorhabditis elegans] hpo-8 gene35092 2262 2452 2402 5256 5431 6892 265.601 280 271.091 613.88371 619.613 790.391 8.51797363061687e-10 1.29809459404048 up -- -- -- K10703|3.2693e-140|cel:CELE_T15B7.2|hpo-8; Protein HPO-8; K10703 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] (A) Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212) [R] General function prediction only Protein tyrosine phosphatase-like protein, PTPLA Protein CBR-HPO-8 {ECO:0000313|EMBL:CAP36344.1} OS=Caenorhabditis briggsae PE=4 SV=1 S Function unknown Protein HPO-8 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_599 26 35 34 63 67 89 1.861092 2.4194473402 2.38360462046 4.66351 4.99678 6.21576552 0.0043096815832716 1.19887778192177 up -- -- -- -- -- [L] Replication, recombination and repair RAI1 like PD-(D/E)XK nuclease Protein T26F2.3 {ECO:0000313|EMBL:CAN86644.3} OS=Caenorhabditis elegans PE=4 SV=3 L Replication, recombination and repair -- slc-25A21 gene46316 343 356 366 804 902 850 22.6068100296016 23.05301 24.07998 54.518377 58.2853 56.0854272569 5.6395300880033e-08 1.25589645863426 up -- -- -- K15110|0|cel:CELE_R11.1|R11.1; Protein R11.1; K15110 solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21 (A) -- [C] Energy production and conversion Mitochondrial carrier protein Protein R11.1 {ECO:0000313|EMBL:CAB04651.3} OS=Caenorhabditis elegans PE=3 SV=3 C Energy production and conversion Protein R11.1 [Caenorhabditis elegans] col-45 gene28 8798 5957 2775 271 902 436 558.7148 345.39934449 166.24573 18.329926 59.24862 29.027553 0.00141399298726237 -3.45297374164001 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-45, isoform a {ECO:0000313|EMBL:CCD71706.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein COL-45 [Caenorhabditis elegans] nhr-57 gene34170 488 368 341 1174 1562 1975 17.3173800339133 13.3799700255095 13.0975700340938 44.1277000080328 58.5894 70.6544000000062 2.50593078075161e-06 1.97006050891555 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Nuclear receptor NHR-57 {ECO:0000313|EMBL:AAK17978.1} (Fragment) OS=Caenorhabditis elegans PE=2 SV=1 K Transcription nuclear receptor NHR-57 [Caenorhabditis elegans] F53F1.2 gene37886 1068 1176 1327 3092 2792 2573 51.81925 53.66153 58.46633 139.1603357409 140.0642176831 119.34430869029 4.49703969567293e-10 1.23610462746023 up [R] General function prediction only -- -- -- [R] General function prediction only Aldo/keto reductase family Protein F53F1.2 {ECO:0000313|EMBL:CAB03127.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F53F1.2 [Caenorhabditis elegans] C32H11.4 gene20310 10284 11174 7337 2082 1546 144 666.043 705.842 464.019 133.649 97.1957 9.15254 3.59961890120231e-13 -2.94494568207919 down -- -- -- -- -- -- -- CUB-like domain Protein C32H11.4 {ECO:0000313|EMBL:CAB05131.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein C32H11.4 [Caenorhabditis elegans] W09C2.8 gene19007 92 78 51 1 14 7 665.596 532.602 373.458 18.9197 105.125 68.7424 1.52534310367332e-08 -3.33313791580827 down -- -- -- -- -- -- -- -- Protein W09C2.8 {ECO:0000313|EMBL:CAX65078.1} OS=Caenorhabditis elegans PE=4 SV=1 P Inorganic ion transport and metabolism Protein W09C2.8 [Caenorhabditis elegans] C03G6.6 gene35296 216 232 102 35 73 39 16.3491 17.5017 7.69146 2.67659 5.54937 3.02941 0.00636307363112853 -1.91124472835878 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C03G6.6 {ECO:0000313|EMBL:CCD62692.1} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C03G6.6 [Caenorhabditis elegans] nhr-221 gene33964 30 39 31 9 14 15 1.670303 2.1099286347 1.7048735827 0.5734968676 0.7967674103 0.874433 0.00788192423725088 -1.40173993264569 down -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- -- -- Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-221 {ECO:0000313|EMBL:CCD63572.1} OS=Caenorhabditis elegans PE=3 SV=2 K Transcription Protein NHR-221 [Caenorhabditis elegans] F56F4.3 gene1422 26 41 29 13 11 8 1.10825 1.7344 1.20556 0.56706 0.472666 0.369777 0.00265608510255621 -1.59370250263337 down -- -- Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [T] Signal transduction mechanisms Sodium:neurotransmitter symporter family Transporter {ECO:0000256|RuleBase:RU003732} OS=Caenorhabditis elegans PE=3 SV=2 P Inorganic ion transport and metabolism Protein F56F4.3 [Caenorhabditis elegans] spch-2 gene1485 100 131 126 65 49 58 16.8425 21.1275 20.9125 11.2124 8.14791 9.72394 0.00419777321225153 -1.06120867666711 down -- -- -- -- -- -- -- -- Protein T27A3.4 {ECO:0000313|EMBL:CCD72004.1} OS=Caenorhabditis elegans PE=4 SV=1 H Coenzyme transport and metabolism Protein T27A3.4 [Caenorhabditis elegans] Y42H9AR.5 gene18445 119 141 108 46 60 57 61.44383 70.24237 52.95695 27.56957 30.17995 27.34963 0.00110031570445061 -1.18170085219471 down -- -- -- -- -- -- -- -- Protein Y42H9AR.5 {ECO:0000313|EMBL:CCD71170.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y42H9AR.5 [Caenorhabditis elegans] acs-19 gene10303 5198 5028 7716 17814 17840 22890 133.172342 129.639969995 198.43716269 471.3029053 461.32229 592.41595 4.87911467927426e-12 1.70009212994448 up [I] Lipid transport and metabolism Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; K01895|0|cel:CELE_C36A4.9|acs-19; Protein ACS-19, isoform B; K01895 acetyl-CoA synthetase [EC:6.2.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200) [I] Lipid transport and metabolism AMP-binding enzyme;; AMP-binding enzyme C-terminal domain Acetyl-coenzyme A synthetase {ECO:0000256|RuleBase:RU361147} OS=Caenorhabditis elegans PE=3 SV=1 G Carbohydrate transport and metabolism Protein ACS-19, isoform a [Caenorhabditis elegans] Y70C5A.3 gene39256 96 111 113 255 206 281 2.85745 3.31179 3.33891 7.60816 6.18887 8.47702 7.12623040345965e-05 1.20622916298853 up -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein Y70C5A.3 {ECO:0000313|EMBL:CAP09189.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein Y70C5A.3 [Caenorhabditis elegans] C05D11.5 gene11122 738 670 435 1768 2003 2072 28.274364 20.90559113 16.7038593131 104.661170392591 109.694072123 118.502931009578 3.83769198983738e-16 1.65684103124826 up [G] Carbohydrate transport and metabolism -- -- -- [G] Carbohydrate transport and metabolism Xylose isomerase-like TIM barrel Hydroxypyruvate isomerase {ECO:0000256|PIRNR:PIRNR006241} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 S Function unknown Protein C05D11.5 [Caenorhabditis elegans] far-3 gene37755 2586 2069 2722 7932 7779 10275 497.891 374.43 496.751 1546.13 1437.69 1971.99 2.72531695800931e-13 1.80992191318935 up -- -- Molecular Function: lipid binding (GO:0008289);; -- -- -- -- Nematode fatty acid retinoid binding protein (Gp-FAR-1) Protein FAR-3 {ECO:0000313|EMBL:CAB01422.1} OS=Caenorhabditis elegans PE=4 SV=1 TZ Signal transduction mechanisms;; Cytoskeleton Protein FAR-3 [Caenorhabditis elegans] Y53C12B.7 gene7770 205 256 274 45 46 60 34.97458 40.66372 43.4201 7.74684 7.34271 10.0504 5.53433603967659e-14 -2.28939088344878 down -- -- -- -- -- -- -- -- Protein Y53C12B.7 {ECO:0000313|EMBL:CAE18037.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y53C12B.7 [Caenorhabditis elegans] cyp-14A2 gene45300 79 105 72 41 40 29 3.22494 4.36961 2.93345 1.72654 1.69354 1.20794 0.00212438251848848 -1.22716267558025 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-14A2 {ECO:0000313|EMBL:CAA90615.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-14A2 [Caenorhabditis elegans] oac-17 gene3717 6 12 9 39 54 26 0.196293 0.378638 0.289602 1.26046 1.71943 0.825882 0.000972560279615805 2.13249390990421 up [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-17 {ECO:0000313|EMBL:CAB02970.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein OAC-17 [Caenorhabditis elegans] K08D9.2 gene33846 400 312 152 17 53 24 16.6458 12.6324 6.15547 0.692193 2.13955 0.98572 0.000269951932074692 -3.20763669701782 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein K08D9.2 {ECO:0000313|EMBL:CCD72793.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein K08D9.2 [Caenorhabditis elegans] C29F3.7 gene38670 4299 5215 3093 1097 916 197 182.940926 210.64534 125.03129 45.888294 37.1390169404 8.264166 7.58524406493446e-08 -2.5235747027519 down -- -- -- -- -- -- -- CUB-like domain Protein C29F3.7, isoform a {ECO:0000313|EMBL:CAB02803.3} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein C29F3.7, isoform a [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_744 154 177 125 64 50 71 1.86638 2.09478 1.48392 0.765083 0.594994 0.847186 0.000117336092361482 -1.30922308264372 down -- -- -- -- -- [R] General function prediction only Reverse transcriptase (RNA-dependent DNA polymerase);; Endonuclease-reverse transcriptase;; Endonuclease/Exonuclease/phosphatase family Reverse transcriptase {ECO:0000313|EMBL:AAC72298.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown PREDICTED: craniofacial development protein 2-like [Camponotus floridanus] C18H9.6 gene6649 2315 2813 2052 1405 974 208 299.5414 333.49131 257.13812 175.53707 118.24335 28.67885 0.00108075450252344 -1.48454831857252 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFP07724.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein C18H9.6 [Caenorhabditis elegans] icl-1 gene33104 20137 13457 22406 64616 74530 94866 318.113061893 207.94482 346.7200867383 1009.3000499914 1153.500100021 1463.6000705664 2.63809342130072e-10 2.05692645718637 up [C] Energy production and conversion Molecular Function: isocitrate lyase activity (GO:0004451);; Molecular Function: malate synthase activity (GO:0004474);; Biological Process: glyoxylate cycle (GO:0006097);; Biological Process: carboxylic acid metabolic process (GO:0019752);; -- -- [C] Energy production and conversion Malate synthase;; Isocitrate lyase family;; Phosphoenolpyruvate phosphomutase Malate synthase {ECO:0000256|RuleBase:RU000555} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 R General function prediction only Protein ICL-1, isoform a [Caenorhabditis elegans] sdha-1 gene43718 5747 5080 4640 10693 10243 10891 126.1557 109.3261 102.5218 234.751 222.265 239.873 2.47040423900569e-07 1.03320174341696 up [C] Energy production and conversion Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; K00234|0|cel:CELE_C03G5.1|sdha-1; Protein SDHA-1; K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] (A) Citrate cycle (TCA cycle) (ko00020);; Oxidative phosphorylation (ko00190);; Carbon metabolism (ko01200) [C] Energy production and conversion FAD binding domain;; Fumarate reductase flavoprotein C-term;; Pyridine nucleotide-disulphide oxidoreductase;; Thi4 family;; Glucose inhibited division protein A CBN-SDHA-1 protein {ECO:0000313|EMBL:EGT34444.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 C Energy production and conversion Protein SDHA-1 [Caenorhabditis elegans] col-38 gene7335 2601 2992 3170 1580 1193 1007 186.491 207.368 223.202 115.816 84.0942 72.5258 6.90073148981186e-10 -1.22169419489216 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-38 {ECO:0000313|EMBL:CAA90250.1} OS=Caenorhabditis elegans PE=4 SV=2 J Translation, ribosomal structure and biogenesis Protein COL-38 [Caenorhabditis elegans] T05A8.6 gene5134 94 55 40 1 18 1 12.97031 7.13219 4.97966 0.27362400888 2.094307 0.270664 0.000959755145689388 -3.24699625138234 down -- -- -- -- -- -- -- Domain of unknown function (DUF281) Protein T05A8.6 {ECO:0000313|EMBL:CCD73589.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein T05A8.6 [Caenorhabditis elegans] T25B9.9 gene19472 5050 4889 4604 11776 10727 12140 208.3393 198.333437 190.72667 500.4873 450.6616 507.4449 2.39284137217861e-10 1.24458623253331 up -- -- Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: pentose-phosphate shunt (GO:0006098);; Biological Process: oxidation-reduction process (GO:0055114);; K00033|0|cbr:CBG17632|Hypothetical protein CBG17632; K00033 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] (A) Pentose phosphate pathway (ko00030);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200) [G] Carbohydrate transport and metabolism 6-phosphogluconate dehydrogenase, C-terminal domain;; NAD binding domain of 6-phosphogluconate dehydrogenase 6-phosphogluconate dehydrogenase, decarboxylating {ECO:0000256|PIRNR:PIRNR000109, ECO:0000256|RuleBase:RU000485} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 R General function prediction only Protein T25B9.9 [Caenorhabditis elegans] R05G9R.1 gene6568 525 437 358 160 192 164 8.75451 7.39817 5.6593 2.557264 3.155641 2.716854 6.61409826156145e-07 -1.36301534968182 down -- -- -- -- -- -- -- -- Protein R05G9R.1 {ECO:0000313|EMBL:CCD68211.1} OS=Caenorhabditis elegans PE=4 SV=4 R General function prediction only Protein R05G9R.1 [Caenorhabditis elegans] lipl-5 gene32971 4618 4276 4638 10343 11132 14027 251.3511658424 228.38408715337 253.346283300668 577.604351390432 597.972197359733 757.24116790501 2.06626638478574e-09 1.38492417799076 up [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; K01052|0|cbr:CBG01370|Hypothetical protein CBG01370; K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] (A) Steroid biosynthesis (ko00100);; Lysosome (ko04142) [I] Lipid transport and metabolism Partial alpha/beta-hydrolase lipase region;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family Lipase {ECO:0000256|PIRNR:PIRNR000862} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein LIPL-5, isoform a [Caenorhabditis elegans] glna-2 gene7142 254 209 228 471 532 594 8.70919537800037 7.281579772 7.86156243715813 16.385121617643 18.505274151302 20.7008978960011 2.38038086997871e-06 1.20162966088483 up [E] Amino acid transport and metabolism Molecular Function: glutaminase activity (GO:0004359);; Biological Process: glutamine metabolic process (GO:0006541);; K01425|0|cel:CELE_DH11.1|glna-2; Protein GLNA-2; K01425 glutaminase [EC:3.5.1.2] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; D-Glutamine and D-glutamate metabolism (ko00471) [E] Amino acid transport and metabolism Glutaminase;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat Putative uncharacterized protein {ECO:0000313|EMBL:EGT38648.1} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 TU Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport Protein GLNA-2 [Caenorhabditis elegans] pqn-60 gene33013 201 257 223 620 607 612 59.2508 69.4508 61.4307 191.354 168.593 180.942 5.6215091241179e-09 1.4258192932344 up -- -- -- -- -- -- -- Domain of unknown function DUF148 Protein PQN-60 {ECO:0000313|EMBL:CCD64483.1} OS=Caenorhabditis elegans PE=1 SV=1 K Transcription Protein PQN-60 [Caenorhabditis elegans] clec-20 gene4718 160 150 74 5 20 6 7.4762 6.78021 3.33752 0.260253 0.925161 0.309642 1.72669748763925e-06 -3.63783866574981 down -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms Lectin C-type domain;; CUB domain Protein CLEC-20 {ECO:0000313|EMBL:CCD63700.1} OS=Caenorhabditis elegans PE=4 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein CLEC-20 [Caenorhabditis elegans] cyp-33C1 gene33487 254 216 145 51 62 64 7.08052053 6.169921579 6.57525060391504 2.3258782923 3.58261733547534 1.72997007206607 2.97081486272633e-05 -1.8044869064725 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17955|0|cel:CELE_C45H4.2|cyp-33C1; Protein CYP-33C1; K17955 cytochrome P450, family 33 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-33C1 {ECO:0000313|EMBL:CCD67429.1} OS=Caenorhabditis elegans PE=3 SV=2 S Function unknown Protein CYP-33C1 [Caenorhabditis elegans] Y82E9BL.18 gene9713 79 108 106 56 27 18 4.60983267439 6.1941251987 5.94635468711 3.31837943217 1.40245193216 1.0967896299 7.91136142118152e-05 -1.54736187641404 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein Y82E9BL.18 {ECO:0000313|EMBL:CCD73905.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein Y82E9BL.18 [Caenorhabditis elegans] C49A9.10 gene17193 1023 1173 1220 535 564 519 90.1401267005852 118.1141243075 143.48706202264 107.01274812703 96.0952702944 91.08209006233 1.11446691035078e-06 -1.08532534096725 down -- -- -- -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion Oxidoreductase-like protein, N-terminal Protein C49A9.10 {ECO:0000313|EMBL:CCD67630.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C49A9.10 [Caenorhabditis elegans] F54H5.2 gene6624 68 86 78 34 31 42 11.797139000195 11.8718010006424 12.29919862715 5.01696100201825 4.361844 6.58500800000185 0.00682448313647308 -1.12325701333176 down [RTKL] General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; -- -- [T] Signal transduction mechanisms Protein kinase domain;; Protein tyrosine kinase Protein F54H5.2 {ECO:0000313|EMBL:CCD68187.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein F54H5.2 [Caenorhabditis elegans] F09C6.12 gene39357 75 80 38 8 18 17 105.4687 60.3255 22.54182 2.16378 4.271347127 38.3472 0.000880944464667923 -2.17235303332771 down -- -- -- -- -- -- -- -- Protein F09C6.12 {ECO:0000313|EMBL:CAI79123.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein F09C6.12 [Caenorhabditis elegans] oac-23 gene14138 139 139 87 33 37 31 4.26789 4.18286 2.536456 0.976558029 1.1649270817 0.943685 2.22945392427675e-06 -1.86181466496101 down [I] Lipid transport and metabolism Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; -- -- -- -- Acyltransferase family Protein OAC-23 {ECO:0000313|EMBL:CCD70193.1} OS=Caenorhabditis elegans PE=4 SV=1 H Coenzyme transport and metabolism Protein OAC-23 [Caenorhabditis elegans] F21G4.3 gene44164 41 41 46 6 5 20 2.7598 2.78451039 3.09624 0.442481000004601 0.371157000087212 1.395451506 2.29620344219817e-05 -2.049569239322 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein F21G4.3 {ECO:0000313|EMBL:CAB02666.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein F21G4.3 [Caenorhabditis elegans] F10F2.2 gene10531 711 626 610 1642 1745 2120 9.90096 8.80682 8.53562 23.33039 24.4895 29.7438 3.54000840617878e-13 1.49299316128202 up [F] Nucleotide transport and metabolism -- K01952|0|cel:CELE_F10F2.2|F10F2.2; Protein F10F2.2; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] (A) Purine metabolism (ko00230) [F] Nucleotide transport and metabolism CobB/CobQ-like glutamine amidotransferase domain;; AIR synthase related protein, C-terminal domain;; AIR synthase related protein, N-terminal domain Putative uncharacterized protein {ECO:0000313|EMBL:EGT52023.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 R General function prediction only Protein F10F2.2 [Caenorhabditis elegans] comt-5 gene33445 14 23 12 135 156 150 1.90575 2.97068 1.56482 18.3738 20.1206 19.7452 5.00908102461188e-18 3.16264845176251 up [R] General function prediction only Molecular Function: O-methyltransferase activity (GO:0008171);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism O-methyltransferase;; Methyltransferase domain Protein COMT-5 {ECO:0000313|EMBL:CCD70635.1} OS=Caenorhabditis elegans PE=4 SV=1 I Lipid transport and metabolism Protein COMT-5 [Caenorhabditis elegans] agxt-1 gene7437 885 824 802 1640 1842 2130 43.410855 39.47178 37.773983 79.721008 87.930732 104.201119 2.70130749267077e-08 1.15338176760067 up [E] Amino acid transport and metabolism Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; K00830|0|cel:CELE_T14D7.1|T14D7.1; Protein T14D7.1; K00830 alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51] (A) Alanine, aspartate and glutamate metabolism (ko00250);; Glycine, serine and threonine metabolism (ko00260);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; Peroxisome (ko04146) [R] General function prediction only Aminotransferase class-V;; Aminotransferase class I and II Serine--pyruvate aminotransferase {ECO:0000256|PIRNR:PIRNR000524} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein T14D7.1 [Caenorhabditis elegans] F55G11.7 gene20328 89 80 61 16 8 4 6.39896 5.61459 4.27214 1.15759 0.591203 0.345265 1.8810724911421e-12 -3.05047639916717 down -- -- -- -- -- -- -- CUB-like domain Protein F55G11.7 {ECO:0000313|EMBL:CAB05221.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F55G11.7 [Caenorhabditis elegans] K09H11.7 gene34665 419 286 239 3154 3444 4030 22.4106789 15.32784646 12.9990923 170.724445 187.364029 219.9425088 6.66952738291771e-49 3.48518756369449 up [G] Carbohydrate transport and metabolism -- K01101|0|cel:CELE_K09H11.7|K09H11.7; Protein K09H11.7; K01101 4-nitrophenyl phosphatase [EC:3.1.3.41] (A) -- [P] Inorganic ion transport and metabolism Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Haloacid dehalogenase-like hydrolase Protein K09H11.7 {ECO:0000313|EMBL:CCD67878.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein K09H11.7 [Caenorhabditis elegans] thn-1 gene20128 20 19 11 100 110 170 2.34118 2.17922 1.2655 11.7614 12.3636 19.139 2.41952938218638e-07 2.91913316823315 up -- -- -- -- -- -- -- Thaumatin family Protein THN-1 {ECO:0000313|EMBL:CAA94598.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein THN-1 [Caenorhabditis elegans] C18H7.11 gene13350 89 123 79 46 20 26 4.96189 6.70278 4.32353 2.52265 1.12091 1.44315 0.000101779374738146 -1.67148034279787 down -- -- -- -- -- -- -- Transmembrane glycoprotein Protein C18H7.11 {ECO:0000313|EMBL:CCD63296.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown C18H7.11 [Caenorhabditis elegans] C25F9.16 gene40286 49 40 36 19 13 19 78.5777 33.43715 38.55144 40.6215 18.32554 15.4292 0.00847135560885483 -1.30171394320129 down -- -- -- -- -- -- -- -- Protein C25F9.16 {ECO:0000313|EMBL:CBH29654.1} OS=Caenorhabditis elegans PE=4 SV=1 L Replication, recombination and repair Protein C25F9.16 [Caenorhabditis elegans] NA Caenorhabditis_elegans_newGene_583 23 33 24 4 8 6 1.24974 1.7818 1.28651 0.256953 0.446263 0.364341 0.000149040945089855 -2.15792673628293 down -- -- -- -- -- -- -- FTH domain Protein FBXA-223 {ECO:0000313|EMBL:CCD64072.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown -- ins-35 gene40559 456 544 338 146 211 248 576.6991 701.5407 458.844 255.9118 287.1496 355.0104 0.00201213391713479 -1.15136435740299 down -- -- -- -- -- -- -- -- Protein INS-35 {ECO:0000313|EMBL:CAB04546.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein INS-35 [Caenorhabditis elegans] D1081.5 gene2144 81 89 84 36 45 42 6.70893 7.14377 6.80542 3.00529 3.69566 3.50077 0.00994300733551342 -1.05301383940427 down -- -- -- -- -- -- -- -- Protein D1081.5 {ECO:0000313|EMBL:CAB00026.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein D1081.5 [Caenorhabditis elegans] sqt-1 gene8297 2232 2738 2229 5175 5258 5426 120.3100365465 140.571121433 115.1000516795 251.119 272.779669 284.6570824087 6.45101661023128e-09 1.13208504602062 up -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-SQT-1 {ECO:0000313|EMBL:CAP23687.1} OS=Caenorhabditis briggsae PE=4 SV=1 G Carbohydrate transport and metabolism Protein SQT-1 [Caenorhabditis elegans] cyp-13A2 gene7782 260 233 213 424 540 546 9.685332 8.953227 8.2047619817 16.50972 20.359057 20.98489 2.80000827659347e-05 1.08982294785377 up [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; K17861|0|cel:CELE_T10B9.7|cyp-13A2; Protein CYP-13A2; K17861 cytochrome P450, family 13 (A) -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 CRE-CYP-13A2 protein {ECO:0000313|EMBL:EFP13156.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-13A2 [Caenorhabditis elegans] fbxa-75 gene9704 55 66 26 5 10 18 4.08775 4.77866 1.9009 0.421726 0.739949 1.35501 0.0089207846609026 -2.16019982994829 down -- -- -- -- -- -- -- FTH domain Protein FBXA-75 {ECO:0000313|EMBL:CCD73909.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-75 [Caenorhabditis elegans] ugt-29 gene33096 2941 3747 3759 986 883 803 106.8927 136.5564 135.967 36.901827 32.4282300000046 29.2555400000113 3.57190116867559e-24 -1.97483931254034 down [GC] Carbohydrate transport and metabolism;; Energy production and conversion Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; -- -- [GC] Carbohydrate transport and metabolism;; Energy production and conversion UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain Protein UGT-29, isoform a {ECO:0000313|EMBL:CCD72462.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein UGT-29, isoform a [Caenorhabditis elegans] sulp-7 gene44560 254 250 249 529 519 543 10.394585448 8.9688351982 9.640964739 18.8511699049802 18.2858500004636 19.1241000113727 3.16299496869422e-05 1.07173350293672 up [P] Inorganic ion transport and metabolism Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [P] Inorganic ion transport and metabolism Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain Protein SULP-7, isoform d {ECO:0000313|EMBL:CAA92028.2} OS=Caenorhabditis elegans PE=2 SV=1 S Function unknown Protein SULP-7, isoform d [Caenorhabditis elegans] cts-1 gene12399 13970 14339 15894 39173 38835 39926 473.826319 468.11234 545.07531 1289.70730800004 1314.10471 1347.544711 2.26102875350515e-11 1.40853183412071 up [C] Energy production and conversion Molecular Function: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912);; K01647|0|cel:CELE_T20G5.2|cts-1; Protein CTS-1; K01647 citrate synthase [EC:2.3.3.1] (A) Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230) [C] Energy production and conversion Citrate synthase Citrate synthase {ECO:0000256|RuleBase:RU000441} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 C Energy production and conversion Protein CTS-1 [Caenorhabditis elegans] elo-1 gene18967 3406 4091 4051 7768 7804 8528 236.030242312 275.86926620312 277.91519 533.925743799 530.720520366 582.7283168609 1.08287860720022e-07 1.05444222401393 up -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis elegans PE=2 SV=1 T Signal transduction mechanisms Protein ELO-1, isoform a [Caenorhabditis elegans] C36E6.8 gene46668 44 56 45 14 21 17 26.71611 29.03387 23.05613 10.50540762196 9.17093 9.533384 0.00139790425373358 -1.4860929037125 down -- -- -- -- -- -- -- -- Protein C36E6.8 {ECO:0000313|EMBL:CCD66903.1} OS=Caenorhabditis elegans PE=4 SV=1 A RNA processing and modification Protein C36E6.8 [Caenorhabditis elegans] elo-4 gene12075 2014 1710 1012 366 589 361 197.242 162.847 97.4787 36.3148 57.2398 35.4386 0.000776396163137581 -1.85566386707688 down -- -- Cellular Component: integral component of membrane (GO:0016021);; -- -- [I] Lipid transport and metabolism GNS1/SUR4 family Elongation of very long chain fatty acids protein {ECO:0000256|RuleBase:RU361115} OS=Caenorhabditis brenneri (Nematode worm) PE=3 SV=1 R General function prediction only Protein ELO-4 [Caenorhabditis elegans] Y50D4B.4 gene33201 854 877 915 2067 1997 2021 19.8399268890287 22.015419013895 21.8920777531 48.5067095199 46.2892993276267 48.9106271703 5.58155906846826e-09 1.19397319368787 up -- -- Cellular Component: cytoplasm (GO:0005737);; Biological Process: glycoprotein catabolic process (GO:0006516);; -- -- -- -- Domain of unknown function (DUF750);; PQQ enzyme repeat Protein Y50D4B.4 {ECO:0000313|EMBL:CCD72851.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein Y50D4B.4 [Caenorhabditis elegans] clec-101 gene3189 699 826 335 57 118 106 41.6385 49.5806 20.1507 3.50544 7.08561 6.40222 0.000428473552558878 -2.73315715289009 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; Lectin C-type domain Protein CLEC-101 {ECO:0000313|EMBL:CAB02952.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein CLEC-101 [Caenorhabditis elegans] cyp-14A5 gene34541 3745 4671 4866 1211 1122 1091 162.885 206.626 210.22 53.3498 49.4837 48.3326 1.78648846813913e-24 -1.96312787607327 down [Q] Secondary metabolites biosynthesis, transport and catabolism Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [Q] Secondary metabolites biosynthesis, transport and catabolism Cytochrome P450 Protein CYP-14A5 {ECO:0000313|EMBL:CCD65596.1} OS=Caenorhabditis elegans PE=3 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein CYP-14A5 [Caenorhabditis elegans] msp-40 gene5850 260 398 386 164 168 162 120.573 164.561 168.036 81.5874 72.9687 75.2817 0.000252524709223807 -1.0864141070625 down -- -- -- -- -- -- -- MSP (Major sperm protein) domain Major sperm protein {ECO:0000256|RuleBase:RU003425} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein MSP-31 [Caenorhabditis elegans] col-158 gene37226 38804 28699 15022 1337 4879 2225 1959.734691 1425.0464 747.484046 69.948970127844 246.495356 113.73546 0.000151973356600572 -3.29634688040499 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-158 {ECO:0000313|EMBL:CAB02874.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein COL-158 [Caenorhabditis elegans] ttr-14 gene44453 1070 1453 1545 612 548 511 40.69338 56.78758 60.36243 24.74742 21.72862 20.59053 2.94998208718935e-07 -1.29108710594875 down -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein TTR-14 {ECO:0000313|EMBL:CAA92135.1} OS=Caenorhabditis elegans PE=4 SV=1 K Transcription Protein TTR-14 [Caenorhabditis elegans] D1044.1 gene10838 163 167 99 59 63 46 7.446598 7.56305900014579 4.67204800269521 2.91104000016931 2.90461700000163 2.23123500263854 0.000948703252849263 -1.36132770393755 down -- -- -- -- -- -- -- Protein of unknown function (DUF1679);; Ecdysteroid kinase;; Phosphotransferase enzyme family;; Choline/ethanolamine kinase Putative uncharacterized protein {ECO:0000313|EMBL:EFO86629.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 S Function unknown Protein D1044.1 [Caenorhabditis elegans] fbxa-166 gene4730 42 55 40 113 84 131 2.49571 3.36738 2.4691 7.02557 5.18083 8.14274 0.000774791465179727 1.25216322632582 up -- -- -- -- -- -- -- FTH domain Protein FBXA-166 {ECO:0000313|EMBL:CCD63673.1} OS=Caenorhabditis elegans PE=1 SV=2 R General function prediction only Protein FBXA-166 [Caenorhabditis elegans] fbxa-50 gene9698 119 144 93 31 47 33 5.1912600000001 6.4091 4.04091927 1.492929 2.076499 1.500509 2.42354747227309e-06 -1.68864173969714 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- -- -- FTH domain;; F-box domain Protein FBXA-50, isoform a {ECO:0000313|EMBL:CCD73939.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein FBXA-50, isoform a [Caenorhabditis elegans] aqp-7 gene41580 2068 2361 2009 6874 7008 7173 137.9974 146.0703 128.39924 470.8308 453.0857 467.6281 3.8387361489889e-19 1.70207198534923 up [G] Carbohydrate transport and metabolism Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; K09886|0|cel:CELE_M02F4.8|aqp-7; Protein AQP-7; K09886 aquaglyceroporin related protein, invertebrate (A) -- [G] Carbohydrate transport and metabolism Major intrinsic protein Protein AQP-7 {ECO:0000313|EMBL:CCD66489.1} OS=Caenorhabditis elegans PE=3 SV=2 TV Signal transduction mechanisms;; Defense mechanisms Protein AQP-7 [Caenorhabditis elegans] C27D9.2 gene5818 146 124 67 21 34 27 33.0857 25.5875 14.5216 5.0607 7.32392 6.09336 0.00138052771667905 -2.04673525168895 down -- -- Cellular Component: extracellular space (GO:0005615);; -- -- -- -- Transthyretin-like family Protein C27D9.2 {ECO:0000313|EMBL:CCD65843.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein C27D9.2 [Caenorhabditis elegans] nhr-270 gene33127 33 52 44 101 118 91 1.619228 2.457477 2.4457002373 5.21538 5.45912 4.68179 0.000878612970261873 1.25774389814042 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains) Protein NHR-270 {ECO:0000313|EMBL:CCD71087.1} OS=Caenorhabditis elegans PE=3 SV=2 R General function prediction only Protein NHR-270 [Caenorhabditis elegans] spp-17 gene196 90 98 172 807 650 283 149.591 147.739 270.695 1615.94 1019.47 504.376 0.0084169748593103 2.26401850603189 up -- -- -- -- -- -- -- -- Protein SPP-17 {ECO:0000313|EMBL:CCD68048.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein SPP-17 [Caenorhabditis elegans] F56C3.4 gene41030 0 3 0 21 28 21 0 0.248001 0 1.48783 1.91026 1.42669 2.08393395701624e-09 4.53723924289411 up -- -- -- -- -- -- -- -- Protein F56C3.4 {ECO:0000313|EMBL:CCD69809.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein F56C3.4 [Caenorhabditis elegans] gcy-18 gene20285 188 181 130 291 371 355 2.8256427461 2.840642 1.930070985 4.56255185 5.715187836 5.53926139 0.000373797638364357 1.01983528213042 up [T] Signal transduction mechanisms Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; K01769|0|cel:CELE_ZK896.8|gcy-18; Protein GCY-18; K01769 guanylate cyclase, other [EC:4.6.1.2] (A) Purine metabolism (ko00230) [T] Signal transduction mechanisms Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein kinase domain;; Protein tyrosine kinase Guanylate cyclase {ECO:0000256|RuleBase:RU003431} OS=Caenorhabditis elegans PE=2 SV=1 G Carbohydrate transport and metabolism Protein GCY-18 [Caenorhabditis elegans] F32H5.1 gene37875 524 443 401 1310 1407 1372 32.75195 28.09744 25.571202 82.11687 86.97491 84.85809 1.74433491085965e-13 1.57190242612158 up -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; K01363|0|cel:CELE_F32H5.1|F32H5.1; Protein F32H5.1; K01363 cathepsin B [EC:3.4.22.1] (A) Lysosome (ko04142) [O] Posttranslational modification, protein turnover, chaperones Papain family cysteine protease Protein F32H5.1 {ECO:0000313|EMBL:CAB04249.1} OS=Caenorhabditis elegans PE=3 SV=1 R General function prediction only Protein F32H5.1 [Caenorhabditis elegans] gst-20 gene8946 2438 2104 2013 343 300 418 322.9716 267.9433 260.9545 47.03972 38.8972 55.12901 1.82159334652223e-37 -2.63454804549762 down -- -- Molecular Function: protein binding (GO:0005515);; -- -- [O] Posttranslational modification, protein turnover, chaperones Glutathione S-transferase, N-terminal domain Protein GST-20 {ECO:0000313|EMBL:CAB07700.3} OS=Caenorhabditis elegans PE=1 SV=1 TV Signal transduction mechanisms;; Defense mechanisms Protein GST-20 [Caenorhabditis elegans] R107.5 gene11990 10995 8042 10089 2224 1936 5781 920.9494 652.133 824.3579 187.8399 157.527 480.2725 0.000133106804801056 -1.55572415658964 down -- -- -- -- -- -- -- -- Putative uncharacterized protein {ECO:0000313|EMBL:EFO96587.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 T Signal transduction mechanisms Protein R107.5, isoform b [Caenorhabditis elegans] F21C10.9 gene35978 62 83 34 157 179 129 5.20936 6.97373 2.86233 13.2539 14.9063 10.8094 4.95792227524298e-05 1.36864023307081 up -- -- -- -- -- -- -- Acetyltransferase (GNAT) domain Protein F21C10.9 {ECO:0000313|EMBL:CCD61440.1} OS=Caenorhabditis elegans PE=4 SV=3 Z Cytoskeleton Protein F21C10.9 [Caenorhabditis elegans] grl-25 gene11956 38389 30458 11151 1605 5078 3655 703.837960713059 554.681745414585 208.48177027703 30.2113309080115 93.2199620688337 66.5082416 0.00582815084805973 -2.95875033387442 down -- -- -- -- -- -- -- -- Protein GRL-25, isoform a {ECO:0000313|EMBL:CAD88221.2} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein GRL-25, isoform a [Caenorhabditis elegans] cyn-16 gene8552 5779 5314 5646 12801 12421 13412 236.2501 199.4225 216.5296 529.1959 517.7704 523.6748 1.40946534068969e-09 1.19921594449207 up [O] Posttranslational modification, protein turnover, chaperones Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; K12737|0|cel:CELE_Y17G7B.9|cyn-16; Protein CYN-16; K12737 peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8] (A) -- [O] Posttranslational modification, protein turnover, chaperones Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Protein CYN-16 {ECO:0000313|EMBL:CAA19454.2} OS=Caenorhabditis elegans PE=4 SV=2 O Posttranslational modification, protein turnover, chaperones Protein CYN-16 [Caenorhabditis elegans] bli-1 gene8087 1435 1431 1623 839 708 653 17.26184 16.66832 18.98304 9.64827 8.20661 7.6175 1.5066523579314e-06 -1.03701543511897 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Small acid-soluble spore protein O family;; Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain CRE-BLI-1 protein {ECO:0000313|EMBL:EFO86161.1} OS=Caenorhabditis remanei (Caenorhabditis vulgaris) PE=4 SV=1 J Translation, ribosomal structure and biogenesis Protein BLI-1 [Caenorhabditis elegans] ipla-4 gene730 61 82 88 38 25 42 2.2152993099 2.9689305641 3.18552825323 1.429983 0.9083608979 1.5458344916 0.00578539307421064 -1.14442276863861 down [R] General function prediction only Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Patatin-like phospholipase;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat Protein D1037.5 {ECO:0000313|EMBL:CCD68353.1} OS=Caenorhabditis elegans PE=4 SV=3 U Intracellular trafficking, secretion, and vesicular transport Protein D1037.5 [Caenorhabditis elegans] D2063.1 gene34221 155 143 169 87 63 65 10.2472 9.40864 11.2605 5.93934 4.17196 4.32408 0.0009978504817088 -1.12755867830025 down [R] General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K13953|0|cel:CELE_D2063.1|Protein D2063.1; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase Protein D2063.1 {ECO:0000313|EMBL:CCD68476.1} OS=Caenorhabditis elegans PE=1 SV=3 O Posttranslational modification, protein turnover, chaperones Protein D2063.1 [Caenorhabditis elegans] wrt-8 gene38664 106 123 71 30 44 36 3.67077 4.23041 2.44276 1.0604 1.53597 1.26764 0.00051744011283305 -1.45475939571878 down -- -- Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; -- -- [T] Signal transduction mechanisms Hint module Protein CBR-WRT-4 {ECO:0000313|EMBL:CAP27407.1} OS=Caenorhabditis briggsae PE=4 SV=1 R General function prediction only Protein WRT-8 [Caenorhabditis elegans] Y80D3A.8 gene40125 39 25 24 12 13 6 0.6579946705 0.381611600000002 0.3916446072 0.21063760583452 0.19814194 0.103019800000016 0.00577835446469402 -1.51508948614436 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- -- -- Protein-tyrosine phosphatase;; Domain of unknown function Protein Y80D3A.8 {ECO:0000313|EMBL:CAB60442.2} OS=Caenorhabditis elegans PE=4 SV=2 T Signal transduction mechanisms Protein Y80D3A.8 [Caenorhabditis elegans] F07G11.4 gene35268 597 523 289 52 120 52 23.025736456 19.8668834 10.9013219086 1.98664800000907 4.5749205 2.03839826887 3.01472751052683e-05 -2.66089610225913 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein F07G11.4 {ECO:0000313|EMBL:CCD64332.1} OS=Caenorhabditis elegans PE=4 SV=1 G Carbohydrate transport and metabolism Protein F07G11.4 [Caenorhabditis elegans] clec-42 gene39871 463 623 295 1313 1581 1342 16.0191 20.787 9.7646 44.3111 52.532 45.1194 3.17668234663045e-13 1.60911632928739 up -- -- -- -- -- [TV] Signal transduction mechanisms;; Defense mechanisms CUB domain;; Lectin C-type domain Protein CLEC-42 {ECO:0000313|EMBL:CAB04128.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-42 [Caenorhabditis elegans] fmo-2 gene19438 274 318 519 18958 26217 36964 11.1974 13.0486 21.0552 787.11 1080.02 1525.39 9.36521551076901e-17 6.2037634961505 up [P] Inorganic ion transport and metabolism Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; K00485|0|cel:CELE_K08C7.5|fmo-2; Protein FMO-2; K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A) Drug metabolism - cytochrome P450 (ko00982) [Q] Secondary metabolites biosynthesis, transport and catabolism Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain;; Pyridine nucleotide-disulphide oxidoreductase Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332} OS=Caenorhabditis elegans PE=2 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein FMO-2 [Caenorhabditis elegans] F18F11.4 gene13288 57 74 48 14 3 1 2.42522 3.08886 2.00282 0.595479 0.154137 0.0806535 2.59261944526904e-11 -3.3290998512003 down -- -- -- -- -- [S] Function unknown Glycosyltransferase family 92 Protein F18F11.4 {ECO:0000313|EMBL:CCD69673.1} OS=Caenorhabditis elegans PE=4 SV=4 S Function unknown Protein F18F11.4 [Caenorhabditis elegans] F49D11.6 gene2995 69 48 73 129 113 173 4.687189 3.385042 5.043800756974 9.097464 8.007309 11.93467 0.00156666038807113 1.12045172302582 up -- -- Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; -- -- [MW] Cell wall/membrane/envelope biogenesis;; Extracellular structures Sulfotransferase family Protein F49D11.6 {ECO:0000313|EMBL:CCD71539.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein F49D11.6 [Caenorhabditis elegans] drd-50 gene14222 355 526 396 174 143 33 35.25 49.6907 38.0323 17.0292 13.6015 3.25437 1.01385138521684e-05 -1.87812414792902 down -- -- -- -- -- -- -- ShK domain-like Protein F49F1.1 {ECO:0000313|EMBL:CCD66745.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein F49F1.1 [Caenorhabditis elegans] C13A2.10 gene35261 115 95 43 0 7 4 8.06372 6.6614 2.987073 0 0.515934 0.339039 7.87439032633393e-06 -4.52788416249305 down -- -- -- -- -- -- -- Methyltransferase FkbM domain Protein C13A2.10 {ECO:0000313|EMBL:CCD63102.2} OS=Caenorhabditis elegans PE=4 SV=2 S Function unknown Protein C13A2.10 [Caenorhabditis elegans] sodh-2 gene37246 238 305 259 72 63 55 13.91488 17.80181 14.60069 4.2734 3.56838 2.936596 1.71027649945909e-12 -2.08580177815373 down [R] General function prediction only Biological Process: oxidation-reduction process (GO:0055114);; K13953|0|cel:CELE_K12G11.4|sodh-2; Protein SODH-2; K13953 alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1] (A) Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Degradation of aromatic compounds (ko01220) [Q] Secondary metabolites biosynthesis, transport and catabolism Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase CBN-SODH-2 protein {ECO:0000313|EMBL:EGT60304.1} OS=Caenorhabditis brenneri (Nematode worm) PE=4 SV=1 Q Secondary metabolites biosynthesis, transport and catabolism Protein SODH-2 [Caenorhabditis elegans] Y57G11C.6 gene24554 67 100 103 42 56 34 2.483158 3.71248 3.82453 1.600253 2.046876 1.303287 0.00979154851459925 -1.0394229843855 down -- -- Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; -- -- [T] Signal transduction mechanisms Protein-tyrosine phosphatase Protein Y57G11C.6 {ECO:0000313|EMBL:CAB16508.1} OS=Caenorhabditis elegans PE=4 SV=1 U Intracellular trafficking, secretion, and vesicular transport Protein Y57G11C.6 [Caenorhabditis elegans] Y43F8B.20 gene40318 76 85 46 151 162 189 2.683517954 3.3350588663 2.6739395 5.430636 6.522424 6.308207 0.000134757995889711 1.2704955049003 up -- -- -- -- -- -- -- Domain of unknown function (DUF19) Protein Y43F8B.20 {ECO:0000313|EMBL:CAR31505.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein Y43F8B.20 [Caenorhabditis elegans] C49A9.6 gene17202 253 263 230 463 502 642 12.66851 12.509331 11.447620100162 22.8755500183068 24.299219 31.256695 1.79029053136301e-05 1.10042941541824 up -- -- -- -- -- -- -- Protein of unknown function (DUF272) Protein C49A9.6 {ECO:0000313|EMBL:CCD67625.1} OS=Caenorhabditis elegans PE=4 SV=1 CG Energy production and conversion;; Carbohydrate transport and metabolism Protein C49A9.6 [Caenorhabditis elegans] W06H8.2 gene34819 214 195 171 2541 2271 3562 9.232119 8.31096 6.983648 108.6236 95.49515 152.4018 1.89291524568324e-16 3.84480406509742 up [C] Energy production and conversion Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [CR] Energy production and conversion;; General function prediction only NADH:flavin oxidoreductase / NADH oxidase family Protein W06H8.2 {ECO:0000313|EMBL:CCD72164.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein W06H8.2 [Caenorhabditis elegans] clec-66 gene8807 2160 3176 3403 615 481 472 122.518 176.45 189.372 34.5478 26.7345 26.4991 1.47984542712782e-11 -2.48626368882511 down -- -- -- -- -- -- -- von Willebrand factor type A domain;; von Willebrand factor type A domain;; Lectin C-type domain Protein CLEC-66 {ECO:0000313|EMBL:CAB03059.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein CLEC-66 [Caenorhabditis elegans] Y49E10.18 gene12921 654 761 634 1163 1292 1883 47.5551 52.3107 43.4375 83.8391 88.8566 134.3 0.00656762441322238 1.07598244852637 up -- -- Biological Process: lipid metabolic process (GO:0006629);; -- -- [I] Lipid transport and metabolism Lipase (class 3) Protein Y49E10.18 {ECO:0000313|EMBL:CAB11554.2} OS=Caenorhabditis elegans PE=4 SV=2 K Transcription Protein Y49E10.18 [Caenorhabditis elegans] nhr-21 gene6888 901 736 1063 1840 2107 3054 37.8085628571359 30.9302790353903 44.07833515 76.8979402034098 89.0623730148666 130.308054310742 0.00142159454919043 1.36889435425032 up -- -- Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; -- -- [T] Signal transduction mechanisms Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor Protein NHR-21, isoform e {ECO:0000313|EMBL:CCD69793.1} OS=Caenorhabditis elegans PE=3 SV=1 E Amino acid transport and metabolism Protein NHR-21, isoform e [Caenorhabditis elegans] K09D9.1 gene34128 480 502 536 178 199 246 39.0818 40.0225 43.3364 14.6171 16.0883 20.075 4.30476986764979e-07 -1.29120873205853 down -- -- -- -- -- -- -- -- Protein K09D9.1 {ECO:0000313|EMBL:CCD61369.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein K09D9.1 [Caenorhabditis elegans] col-63 gene2074 2071 2214 2240 1192 883 884 83.0829 89.3976 90.2385 47.805 35.7571 35.6309 1.75298011475106e-08 -1.14934945275271 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein COL-63 {ECO:0000313|EMBL:CAB03513.1} OS=Caenorhabditis elegans PE=4 SV=1 W Extracellular structures Protein COL-63 [Caenorhabditis elegans] Y52E8A.3 gene5699 285 255 132 50 54 34 88.3397 72.9853 39.5785 16.5836 16.0025 10.8628 0.000379844862288125 -2.29330653986554 down [OC] Posttranslational modification, protein turnover, chaperones;; Energy production and conversion Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; -- -- [R] General function prediction only Thioredoxin-like;; AhpC/TSA family;; Thioredoxin;; Redoxin;; Thioredoxin-like domain;; SCO1/SenC;; Thioredoxin Protein Y52E8A.3 {ECO:0000313|EMBL:CCD62413.1} OS=Caenorhabditis elegans PE=4 SV=1 O Posttranslational modification, protein turnover, chaperones Protein Y52E8A.3 [Caenorhabditis elegans] K01A2.4 gene4291 71 116 79 397 450 352 6.98124 10.17081 9.02515 29.69160240712 37.94958 29.1631 1.41004853549313e-15 2.16483170977035 up -- -- -- -- -- -- -- -- Protein K01A2.4 {ECO:0000313|EMBL:CCD61953.1} OS=Caenorhabditis elegans PE=4 SV=2 R General function prediction only Protein K01A2.4 [Caenorhabditis elegans] T16G1.7 gene37723 1326 1669 1258 555 536 532 40.44724 54.27719 39.68521 17.96688 16.2497 15.41919 4.41695485191355e-11 -1.39753045466973 down -- -- -- -- -- -- -- Protein of unknown function (DUF1679);; Ecdysteroid kinase;; Phosphotransferase enzyme family Protein T16G1.7 {ECO:0000313|EMBL:CAB63314.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T16G1.7 [Caenorhabditis elegans] ZK1320.9 gene7749 1642 1610 2116 4439 5216 6460 55.73394678 52.92381254 69.40990911 149.75085 172.889299 214.8336373 4.82382460785843e-08 1.58003466170199 up [C] Energy production and conversion Molecular Function: catalytic activity (GO:0003824);; Biological Process: acetyl-CoA metabolic process (GO:0006084);; -- -- [C] Energy production and conversion Acetyl-CoA hydrolase/transferase C-terminal domain;; Acetyl-CoA hydrolase/transferase N-terminal domain Protein ZK1320.9 {ECO:0000313|EMBL:CAA87047.1} OS=Caenorhabditis elegans PE=1 SV=1 C Energy production and conversion Protein ZK1320.9 [Caenorhabditis elegans] T23F1.5 gene38721 2119 1528 1032 328 466 302 21.4221 14.7138 9.92739 3.13078 4.48103 2.89778 0.000508766616767008 -2.10249877138358 down -- -- -- -- -- -- -- Zona pellucida-like domain Protein T23F1.5 {ECO:0000313|EMBL:CAB03404.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein T23F1.5 [Caenorhabditis elegans] slc-17.9 gene44119 240 148 190 102 72 104 9.965145586 6.1262946078 8.19042 4.31395418 3.08538554 4.303910039594 0.00377169062093848 -1.06417933137965 down [GEPR] Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; -- -- [G] Carbohydrate transport and metabolism Major Facilitator Superfamily Protein SLC-17.9 {ECO:0000313|EMBL:CAA87340.1} OS=Caenorhabditis elegans PE=4 SV=1 V Defense mechanisms Protein T09B9.2 [Caenorhabditis elegans] F55G11.4 gene20334 55263 65837 40243 7857 6916 4334 4015.03 4756.56 2893.51 579.812 499.691 316.159 3.85102573443141e-13 -3.08753322457723 down -- -- -- -- -- -- -- CUB-like domain Protein F55G11.4 {ECO:0000313|EMBL:CAB05224.1} OS=Caenorhabditis elegans PE=4 SV=1 R General function prediction only Protein F55G11.4 [Caenorhabditis elegans] nspc-10 gene45017 560 593 638 224 270 206 1113.364 1043.365 1189.28 530.717 507.7939 430.7429 3.04386428650534e-08 -1.36264074168894 down -- -- -- -- -- -- -- -- Protein NSPC-10 {ECO:0000313|EMBL:CAD54145.1} OS=Caenorhabditis elegans PE=4 SV=1 S Function unknown Protein NSPC-10 [Caenorhabditis elegans] mltn-8 gene32968 123 78 61 7 9 10 2.4841800306 1.605334697 1.26066 0.173164000000012 0.211142570724 0.24072018712 6.42508441249428e-06 -3.34057455629195 down -- -- -- -- -- -- -- Moulting cycle Protein MLTN-8 {ECO:0000313|EMBL:CCD74311.1} OS=Caenorhabditis elegans PE=4 SV=3 R General function prediction only Protein MLTN-8 [Caenorhabditis elegans] col-43 gene35571 48977 39097 19565 1676 6233 2776 2736.32 2023.9 1019.305 89.4015 322.547 147.4593 6.09232418039147e-05 -3.33946276461348 down -- -- Molecular Function: structural constituent of cuticle (GO:0042302);; -- -- [W] Extracellular structures Collagen triple helix repeat (20 copies);; Nematode cuticle collagen N-terminal domain Protein CBR-COL-43 {ECO:0000313|EMBL:CAP30574.1} OS=Caenorhabditis briggsae PE=4 SV=1 W Extracellular structures C. briggsae CBR-COL-43 protein [Caenorhabditis briggsae] C06B8.2 gene38728 125 97 118 523 559 642 5.884515508 4.2092627 5.18994300018003 23.9535687 24.7529577492358 29.064653057 2.3265407691588e-20 2.33514922000448 up -- -- -- -- -- -- -- Protein of unknown function (DUF1647) Protein C06B8.2, isoform c {ECO:0000313|EMBL:CBL87047.1} OS=Caenorhabditis elegans PE=4 SV=1 T Signal transduction mechanisms Protein C06B8.2, isoform c [Caenorhabditis elegans]