>CYP1A1_Hum NM_000499 MLFPISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPW GWPLIGHMLTLGKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDD FKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLE EHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYDHNHQELLSLV NLNNNFGEVVGSGNPADFIPILRYLPNPSLNAFKDLNEKFYSFMQKMVKEHYKTFEKG HIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLV MNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTR DTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIF GMGKRKCIGETIARWEVFLFLAILLQRVEFSVPLGVKVDMTPIYGLTMKHACCEHFQM QLRS >CYP1B1_Hum NM_000104 MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRR RQLRSAPPGPFAWPLIGNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERA IHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQP RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDD PEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKF LRHCESLRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDT LSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFS SFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDG LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYG LTIKPKSFKVNVTLRESMELLDSAVQNLQAKETCQ >CYP2A6_Hum NM_000762 MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMK ISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGY GVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTG GANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQ LYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQE EEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVE AKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPK GTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIG KRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR >CYP2B6_Hum NT_011109.13 + strand MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLR FREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGY GVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSK GALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQ LFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEK EKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVA ERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPK DTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGK GKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR >CYP2C8_Hum M17397 MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTN FSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKG LGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIEDRVQEEAHCLVEELRKTK ASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQ VCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFMDCFLIKMEQ EKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPK GTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSA GKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV >CYP2D6_Hum NM_000106 MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQ LRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQ GVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHS GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLRE VLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEK AKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQ RRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKG TTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR MELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR >CYP2E1_Hum J02843 MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGN LFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGD LPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRK TQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLY NNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKE KHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIG PSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPT LDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL LCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS >CYP2F1_Hum J02906 MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLLLLCSQDMLTSLTK LSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGN GIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLADVRKTE GEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGE LYDILDPRFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASSPRDFIQCFLTKMA EEKEDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQ ARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPK GTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSA GRRLCLGELLARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNLPRPFQLCLRPR >CYP2J2_Hum NM_000775 chr 1 NT_032977.5 (build 33) MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQL FVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKN GLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEEN GQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQ LYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSK HTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQ EKVQVEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPQNVPREVTVDTTLAGYHLPK GTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSI GKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLC >CYP2S1_Hum AC011510 one exon per line 78% to Mmus 2s1 49% to 2B6 47% to 2A13 MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMR LSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGH GVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTE GRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQ TYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQ EEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQ KWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQ GTEVFPLLGSILHEPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSL GKRVCLGEGLAKAEVFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR >CYP2W1_Hum AC073957.7 chromosome 7 clone RP11-449P15 40% to 2F1 MALLLLLFLGLLGLWGLLCACAQDPSPAARWPPGPRPLPLVGNLHLLRLSQQDRSLME LSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGG GIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYR GRPFPLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQ LFNVYPWLGALLQLHRPVLRKIEEVRAILRTLLEARRPHVCPGDPVCSYVDALIQQGQ GDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQ GRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPK GTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSA GRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPRAQALCAVPRP* >CYP3A4_Hum J04449 MAVIPDLAMETWLLLAVSLVLLYL YGTHSHGLFKKLGIPGPTPLPFLGNILSYHK GFCMFDMECHKKYGKVCG FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRR PFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKE MVPIIAQYGDVLVRNLRREAETGKPVTLKD VFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLS IIFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQK HRVDFLQLMIDSQNSKETESHK ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPER FSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQ IPLKLSLGGLLQPEKPVVLKVESRDGTVSGA >CYP3A7_Hum NM_000765 MDLIPNLAVETWLLLAVSLILLYL YGTRTHGLFKKLGIPGPTPLPFLGNALSFRK GYWTFDMECYKKYRKVWG IYDCQQPMLAITDPDMIKTVLVKECYSVFTNRR PFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKE MVPIIAQYGDVLVRNLRREAETGKPVTLKH VFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLS IKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQK HRVDFLQLMIDSQNSKDSETHK ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNK APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPER FSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQ IPLKLRFGGLLLTEKPIVLKAESRDETVSGA >CYP4A11_Hum NT_04852.13 MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQE LQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRS DPKSHGSYRFLAPWI GYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVML DKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDR NSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHT DQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAK MENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITW NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPK GIMVLLSIYGLHHNPKVWPNPE VFDPFRFAPGSAQHSHAFLPFSGGSR NCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL* >CYP4B1_Hum NM_000779 MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRRTLAKAMDKFPGPPTHWLFGHALE IQETGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRG DPKAPDVYDFFLQWIG RGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIML DKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHR DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHT DQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGAR DEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQW DDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPA GSLISMHIYALHRNSAVWPDPE VFDSLRFSTENASKRHPFAFMPFSAGPR NCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGSGK >CYP4F2_Hum NM_001082 revised exon 2 and C-terminal MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGM IHSSEEGLLYTQSLACTFGDMGCWWVGPWQAVIHIFLPTCIKPVLFAS AAIAPKDKFFYSFLEPWLG DGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMH AKWQLLASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQE KPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGV DDFLQAKAKSKTLDFIDVLLLSK DEDGKKLSDEDIRAEADTFMFE GHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW DDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPK GIICLISVFGTHHNPAVWPDPE VYDPFRFDPENIKERSPLAFIPFSAGPR NCIGQTFAMAEMKVVLALTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS >CYP4V2_Hum formerly CYP4AH1 AC012525 MAGLWLGLVWQKLLLWGAASAVSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHALLMKPDGR EFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEG ILTSSKQIDKSSMYKFLEPWLGLGLLT STGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIIC ETAMGKNIGAQSNDDSEYVRAVYR MSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSV IAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFE GHDTTAAAINWSLYLLGSNPEVQKKVDHELDDV KSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED YFLTAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQG RHPYAYVPFSAGPRNCIG QKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRNADER* >CYP4X1_Hum R56515, R53456, AA652746, AC026935.2 contig 141552-178731 MEFSWLETRWARPFYLAFVFCLALGLLQAIKLYLRRQRLLRDLRPFPAPPTHWFLGHQK FIQDDNMEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPDYAKTLLSRT DPKSQYLQKFSPPLLG KGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMAHSVKMML DKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTN STHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQ KLSRVLNQYTDTIIQERKKSLQAGVKQDNTPKRKYQDFLDIVLSAK DESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPA GITVVLSIWGLHHNPAVWKNPK VFDPLRFSQENSDQRHPYAYLPFSAGSR NCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKL >CYP4Z1_Hum intact mRNA = AY262056 MEPSWLQELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHKE FYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQ DPKSAVSHKILESWV GRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMML NKWEEHIAQNSRLELFQHVSLMTLDSIMKCAFSHQGSIQLD STLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFT EKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAK SENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITW EHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPA GITVFINIWALHHNPYFWEDPQ VFNPLRFSRENSEKIHPYAFIPFSAGL RNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGIHVFAKKVC* >CYP5A1_Hum NM_001061 this gene is 197000 bases long MMEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLG LRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLV ENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQAC DLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFGTPVDSWQAPEDPFVKHCKRFF EFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERR RDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVG QAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLP YLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPE TQVPLQLESKSALGPKNGVYIKIVSR >CYP7A1_Hum NM_000780 AC009927.10 chromosome 8 MMTTSLIWGIAIAACCCLWLILGIRRR QTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAK AFGHRSIDPMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSN SKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPA LVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKA KTHLVVLWASQANTIPATFWSLFQMIR NPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVL DSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDSIIALYPQLMHLDPEIYPDPL TFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFA IHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL* >CYP7B1_Hum NM_004820 AC104939.7 chr 8 MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTR RPGEPPLIKGWLPYLGVVLNLRKDPLRFMKTLQKQHGDTFTVLLG GKYITFILDPFQYQLVIKNHKQLSFRVFSNKLLEKAFSISQLQKNHDMNDELHLCYQFLQGKSLDILLESMMQN LKQVFEPQLLKTTSWDTAELYPFCSSIIFEITFTTIYGKVIVCDNNKFISELRDDFLK FDDKFAYLVSNIPIELLGNVKSIREKIIKCFSSEKLAKMQGWSEVFQSRQDVLEKYYVHEDLEIG AHHLGFLWASVANTIPTMFWAMYYLLRHPEAMAAVRDEIDRLLQSTGQKKGSGFPIHLTREQLDSLICL ESSIFEALRLSSYSTTIRFVEEDLTLSSETGDYCVRKGDLVAIFPPVLHGDPEIFEAPE EFRYDRFIEDGKKKTTFFKRGKKLKCYLMPFGTGTSKCP GRFFALMEIKQLLVILLTYFDLEIIDDKPIGLNYSRLLFGIQYPDSDVLFRYKVKS* >CYP8A1_Hum D83402 AL118525.17 chr 20 MAWAALLGLLVALLLLLLLSRRRTR RPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEKHGDIFT ILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKL TLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLR AGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSV GDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQ GNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVL DSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPE VFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQ FVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP* >CYP8B1_Hum AF090318 AC010192 MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGT VPWLGHAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDP LSFGPILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNE TMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQA GELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQHLFHKMLSVSHSQEKEGISNWLGN MLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQV LGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQE YLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTM PWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSH DVRFRYRLHPTE >CYP11A1_Hum NM_000781 MLAKGLPPRSVLVKGYQTFLSAPREGLGRLRVPTGEGAGISTRS PRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVI DPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMA PEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGER QGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSK ADIYTQNFYWELRQKGSVHHDYRGMLYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMT LQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISV TLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYF RNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPIS FTFWPFNQEATQQ >CYP11B1_Hum NM_000497 MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRR PGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQ VDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPM VDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSS ASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQ ELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNP NVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL QNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQC LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMCPLLTFRAIN >CYP17_Hum NM_000102 MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLP RHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATL DIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATH NGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLV PWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNG NAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQ NVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEV IINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQ ELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAEGST >CYP19_Hum NM_000103 MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGT SSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSS MFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRM VTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQ GYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECM DFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIK EIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGT NIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAI LVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRNSDRCLEH >CYP20A1_Hum AC011737.10 chr 2 (exons 1-11) AC080075.7 (exons 12, 13) MLDFAIFAVTFLLALVGAVLYLYP ASRQAAGIPGITPTEEK DGNLPDIVNSGSLHEFLVNLHERYGPVVSFWFGRRLVVSLGTVDVLKQHINPNKTS DPFETMLKSLLRYQSGGGSVSENHMRKKLYENGVTDSLKSNFALLLK LSEELLDKWLSYPETQHVPLSQHMLGFAMKSVTQMVMGSTFEDDQEVIRFQKNHGT VWSEIGKGFLDGSLDKNMTRKKQYED ALMQLESVLRNIIKERKGRNFSQHIFIDSLVQGNLNDQQ ILEDSMIFSLASCIITAK LCTWAICFLTTSEEVQKKLYEEINQVFGNGPVTPEKIEQLR YCQHVLCETVRTAKLTPVSAQLQDIEGKIDRFIIPRE TLVLYALGVVLQDPNTWPSPHK FDPDRFDDELVMKTFSSLGFSGTQECPELR FAYMVTTVLLSVLVKRLHLLSVEGQVIETKYELVTSSREEAWITVSKRY* >CYP21A2_Hum M26856 MLLLGLLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPD LPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVS RNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVA IEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRF FPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQ LLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSR VPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA HLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAF TLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ >CYP24_Hum NM_000782 MSSPISKSRSLAAFLQQLRSPRQPPRLVTSTAYTSPQPREVPVC PLTAGGETQNAAALPGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLG SFESVHLGSPCLLEALYRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSA FQKKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYSELNKWSFESICLVL YEKRFGLLQKNAGDEAVNFIMAIKTMMSTFGRMMVTPVELHKSLNTKVWQGHTLAWDT IFKSVKACIDNRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSL MWILYNLSRNPQVQQKLLKEIQSVLPENQRPREEDLRNMPYLKACLKESMRLTPGVPF TTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFA HLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLHSGTLVPSRELPI AFCQR >CYP26A1_Hum NM_000783 MGLPALLASALCTFVLPLLLFLAAIKLWDLYCVSGRDRSCALPL PPGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILL GDDRLVSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEV GSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMT RNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICGLRASEAGQGCKDALQLLIE HSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKG LLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGW NVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI LLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFTHFHGEI >CYP26B1_Hum AC007002 MLFEGLDLVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQ GSGFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNTVSNS IGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQ KLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRR GIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIF AAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLD CVIKEVMRLFTPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDP DRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI TLVPVLHPVDGLSVKFFGLDSNQNEILPETEAMLSATV >CYP26C1_Hum AL358613.16 522 amino acids, 6 exons MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQ GSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRK VLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRL DEAQCATLARTFEQLVENLFSLPLDVPFSGLRK GIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELK ESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPD CGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELD GYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRLHYIPFGGGARSCLG QELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL* >CYP27A1_Hum NM_000784 MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAP GAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGP QMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQA LNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAIC YILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWN AIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLM AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE TLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGEL KSVARIVLVPNKKVGLQFLQRQC >CYP27B1_Hum NM_000785 MTQTLKYASRVFHRVRWAPELGASLGYREYHSARRSLADIPGPS TPSFLAELFCKGGLSRLHELQVQGAAHFGPVWLASFGTVRTVYVAAPALVEELLRQEG PRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNN VVCDLVRRLRRQRGRGTGPPALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDT ETFIRAVGSVFVSTLLTMAMPHWLRHLVPGPWGRLCRDWDQMFAFAQRHVE RREAEAA MRNGGQPEKDLESGAHLTHFLFREELPAQSILGNVTELLLAGVD TVSNTLSWALYELS RHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPD KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGF GKRSCMGRRLAELELQMALAQ ILTHFEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR >CYP27C1_Hum AC027142 43% identical to 27A1 assembled gene MQTSAMALLARILRAGLRPAPERGGLLGGGAPRRPQPAGARLPAGARAEDKGAGRPGSPPG GGRAEGPRSLAAMPGPRTLANLAEFFCRDGFSRIHEIQ QKHTREYGKIFKSHFGPQFVVSIADRDMVAQVLRAEGAAPQRANMESWREYRDLRGRATGLISA EGEQWLKMRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSME GVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFC RSWDGLFKFS QIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDT TSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLR LFPVLPGNGRVTQEDLVIGGYLIPKG TQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQ LLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK* >CYP39A1_Hum AC008104 AL035670 note heme region exon corrected 1/18/02 MELISPTVIIILGCLALFLLLQRKNLRRPPCIKGWIPWIGVGFEFGKAPLEFIEKARIK YGPIFTVFAMGNRMTFVTEEEGINVFLKSKKVDFELAVQNIVYRT ASIPKNVFLALHEKLYIMLKGKMGTVNLHQFTGQLTEELHEQLENLGTHGTMDLNNLVR HLLYPVTVNMLFNKSLFSTNKKKIKEFHQYFQVYDEDFEYGSQLPECLLR NWSKSKKWFLELFEKNIPDIKACKSAKDNSM TLLQATLDIVETETSKENSPNYGLLLLWASLSNAVP VAFWTLAYVLSHPDIHKAIMEGISSVFGKAG KDKIKVSEDDLENLLLIKWCVLETIRLKAPGVITRKVVKPVEIL NYIIPSGDLLMLSPFWLHRNPKYFPEPELFKPERW KKANLEKHSFLDCFMAFGSGKFQCPARW FALLEVQMCIILILYKYDCSLLDPLPKQ SYLHLVGVPQPEGQCRIEYKQRI >CYP46_Hum NM_006668 MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPS FLLGHLPCFWKKDEVGGRVLQDVFLDW AKKYGPVVRVNVFHKTSVIVTSPESVK KFLMSTKYNKDSKMYRALQTVFGER LFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAK AAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAK FLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILK AEEGAQDDEGLLDNFVTFFIA GHETSANHLAFTVMELSRQPEIVAR LQAEVDEVIGSKRYLDFEDLGRLQYLSQ VLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLL FSTYVMGRMDTYFEDPLTFNPDRFGPGAPK PRFTYFPFSLGHRSCIGQQFAQ MEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPPPC >CYP51_Hum NM_000786 MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTL SLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVF SFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLE QKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHG KEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQK RRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLA RDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMART PQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGA GRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRS K >CYP1A_Danre NM_131879 AF210727 AY398333 AB078927 AF057713 MALTILPILGPISVSESLVAIITICLVYLLMRLNRTKIPDGLQK LPGPKPLPIIGNVLEIGNNPHLSLTAMSKCYGPVFQIQIGMRPVVVLSGNDVIRQALL KQGEEFSGRPELYSTKFISDGKSLAFSTDQVGVWRARRKLALNALRTFSTVQGKSPKY SCALEEHISNEGLYLVQRLHSVMKADGSFDPFRHIVVSVANVICGICFGRRHSHDDDE LVRLVNMSDEFGKIVGSGNPADFIPFLRILPSTTMKKFLDINERFSKFMKRLVMEHYD TFDKDNIRDITDSLINHCEDRKLDENSNLQVSDEKIVGIVNDLFGAGFDTISTALSWA VVYLVHYPEVQERLQRELDEKIGKDRTPLLSDRANLPLLESFILEIFRHSSFLPFTIP HCTSKDTSLNGYFIPKDTCVFVNQWQVNHDPELWKDPSSFIPDRFLTADGTELNKLEG EKVLVFGLGKRRCIGESIGRAEVFLFLAILLQRLKFTGMPGEMLDMTPEYGLTMKHKR CLLRVTPQPGF >CYP1B_Danre AJ249074 MMDVLLALRDLLQLSTRSVLLSLMVCLMLMFRRRQLVPGPFSWPVIGNAAQLGNTP HFYLSRMAQKYGDVFQIKLGSRNVVVLNGDAIKEALVKKATDFAGRPDFASFRFVSNGKS MAFGNYTPWWKLHRKVAQSTVRNFSTANIQTKQTFEKHIVSEIGELIRLFLNKSREQQFF QPHRYLVVSVANTMSAVCFGNRYAYDDAEFQQVVGRNDQFTKTVGAGSMVDVMPWMQYFP NPIRTLFDQFKELNKEFCAFIELKVSEHRKTISPSHVRDMTDAFIVALDKGLSGGSGVSL DKEFVPPTISDIF GASQDTLSTALQWIILLLVR YPEIQKRLQEDVDRVVDRSRLPTIADQPHLPYLMAFIYEVMRFTSFTPLTIPHS TTKDTSINGYPIPKDTVIFVNQWSLNHDPTKWDQPEVFNPQRFLDEDGSLNKDLTTNVLI FSLGKRRCIGEDVSKIQLFLFTSVLVHQCSFKAESTPNMDYEYGLTLKPKPFKVSVTARD SSDLLDSLVGTSQTPTEKR >CYP1C1_Danre NA17619 79% to CYP1C2 MEAEFGLKSSSIMREWSGQ VQPALIASFIILFFLEACLWVRNLTFKKRLPGPFAWPLVGNAMQLGQMPHITFSKLAKKY GNVYQIRLGCSDIVVLNGDAAIRKALVQHSTEFAGRPNFVSFQMISGGRSLTFTNYSKQW KTHRKVAQSTLRAFSMANSQTRKTFEQHVVGEAMDLVQKFLRLSADGRHFNPAHEATVA AANVICALCFGKRYGHDDPEFRTLLGRVNKFGETVGAGSLVDVMPWLQS FPNPVRSVYQNFKTINKEFFNYVKDKVLQHRDTYDPDVTRDMSDAIIGVIEHGKESTLT KDFVESTVTDLIGAGQDTVSTAMQWMLLLLVKYPSIQSKLQEQIDKVVGRDRLPSIED RCNLAYLDAF IYETMRFTSFVPVTIPHSTTSDVTIEGLHIPKDTVVFINQWSVNHDPQKWSDPHIFNPSR FLDENGALNKDLTSSVMIFSTGKRRCIGEQIAKVEVFLFSAILLHQCKFERDPSQDLSMD CSYGLALKPLHYTISAKLRGKLFGLVSPA >CYP1D1_Danre Danio rerio (zebrafish) GenEMBL NM_001007310 5 introns MNLENISHTATSEVTLILCAFALLLLALHGRRRAPGVPVPPGPRPWPIVG NFLQMEEQVHLSLTNLRVQYGDVFQVKMGSLVVVVLSGYTTIKEALVRQGDA FAGRPDLYTFSAVANGTSMTFSEKYGEAWVLHKKICKNALRTFSQTEPKDSNASCLLE ERICVEAIDMVETLKAQGEEFGDSGIDPVQLLVTSVANVVCTLCFGKRYSHNDKEFLT IVHINNEVLRLFAAGNLADFFPIFRYLPSPSLRKMVEFINRMNNFMERNIMEHLVNFDT NCIRDITDALIAMCEDRQEDKESAVLSNSQIVHSVIDIFGA GFDTIITGLQWSLLYLIKFPNIQDKIVQEI DNQVGMDRLPQFKDRPNMPYTEAFINEVFRHASYMPFTIPHC TTENITLNGYFIPKDTCVFINQYQVNHDI EIWDDPESFRPERFLTLSGHLNKSLTEKVMIFGMGIRRCLGDNIARLEM FVFLTTLLHRLHIENVPGQELDLSSTFGLTMKPRPYRIKIIPRN* >CYP2K6_Danre AF283813 MALIEAFLLQGSPTGTILGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNLHILDLKKTYLSLLE LSKKYGPIYTVYLGPKKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFNRGY GIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFX GNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQ IYNMFPWLRPIVANRNQIVKNLRDTFKQNEELINGVMKTLDPFNPRGIVDSFLIRQQKDE ESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQ AKVQDEIERVIGGRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKK GTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGA GRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTPVVGFTLNPKPHQLCAVKRS >CYP2N13_Danre ctg24224.a Z35723-a834b06.q1c zfishC-a2756d10.q1c 55% to 2N2 MAYTAILETLDVKGILLFMVAFLLVADYLKNRNPPKYPPSPFSVPLLGNIFNVDSKEPHLYLTK LGHAYNNIFSLRLGSDKTVFITGYKMVKEALVTQAENFVDRPNSPVLARVYSGNA GLFFSNGEMWKKQRRFALSTLRNFGLGKKTMELAICEESRFLLEEIDEQK GAAFDPTILLYNAVSNIICQMVFGQRFDYADHQFKTMLKYISKSIQLEGSVWGQ IYEAFPAIMKHLPGPHNDIFSNYDLLKSFVHEVIVKHKAKLDPSEPRDYIDTFLIEMKE KPHERVNGFEEPNLVACVLDLFLAGTESTSNTLCWGLIYLIMYPDVQ EKVQEEIDRVIGNSREPSIADKPNMPYTEAVIHEIMRFGDVIPLNGLRVAARDTTLGECFIPK GTTVLPILHSVLFDENEWETPYKFNPGHFLDKEGKFVRRDAFMPFSA GKRVCLGEQIARIELFLFFVSLFRKFRFSATEGEKLNMDGVIGITRTPHPFKICATAR >CYP2P6_Danre ctg24224.g 77% TO 2p9 MDLLHIYEWIDIKAVLFFACVFLLLSNYIQNKTPKNFPPGPWPLPIIGNLYHIDFNKIHLEVEK LSEKYGSVVSVHLFGQRTVILNGYKQVKEVYIQQGDNVADRPELPMIHDIAGDN GLVAPSGYKWKQQRRFALSTLRNFGLGKKSLEPSINLECHYLNEAISNEN GRPFDPHLLLNNAISNVICVLVFGNRFDYSDHHFQTLLNNINEAMYLDGTIWAQ LYNSHPRIMRLLPGPHKKNITLWNKVIDFARERVKEHRVDYDPSNPRDYVDCFLAEMEK LKDDTAAGFDVENLCICTLDLFVAGTETTSTTLSWSLLYMIKYPEIQ AKVQEEIDRVIGSSRQPSVSDRDNMPYTNAVIHEIQRFGNIAALNLPRAAVKDIQVGKYLIPK GTIVIGNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFS GKRVCLGEQLARMELFLFFTSLLQHFTFSSPAGVEPSFNYKLGTTRAPKPFKLCAVSR >CYP2R1_Danre AL954331.8 zfishG-a628h11.q1cz 77% to 2R1 MISIKRLTSPLSLSW EQTLICLLGLFTTLLILLVIRQLVKQRRPRGFPPGPTPLPIIGNM LSLATEPHVYMKRQSDIHGQ IFSLDLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTK KLAVNCFRYFGTGQRMFERISEECLYFLDAIDQHQGKPFNPKHLVTNAVSNITNLIIFG QRFTYDDGDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLPFGKHQRLFRNANEVYKFL LQIIRRFSQGRVPQSPQHYIDAYLDEMEQSTPDKATSFSQDNLIFSVGELIIAGTETTTN CLRWAMLYMALYPRIQ EKVQMEIDSVLNGRQPAFED RQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRGYTIPKGTMVITNLYSVHFDEKYW SDPSIFCPERFLDCNGKFIRHEAFLPFSI GKRHCLGEQLARLEMFLFFTTLLQRFHLQFSEGFIPSLSAKLGMTLQPQPYSICAIRRQQ* >CYP2U1_Danre ctg13442 63% to 2U1 fugu 57% to 2U1 human zfishG-a1404f04.q1c MDVSAGLLLEYVFSP ANIAGLTALVLVFYVLQEYQWHQTYANIPPGPKPWPIVGNFGGFLVPPLIIKRFXKNSQE FAKVVSNPLSPQAGLIEMSKLYGNIFSIFVGPQLMVVLTGYDAVRDAMLNHTETFSDRPH IPLVTIITKRK GIVFAPYGPLWRTNRRFCHSTLRSFGFGRMSLEPCIHEGLAIIKTELQSLIETAGPSGID LTPLISNAVSNIISLMSLGQRFHHEDKEFRNMRDLMSHGLEISVNTSILLVNVFPWLYYL PFGVFKELRRAELDITAFLKRIIARHRATLDPENPRDFIDMYLVEMLAKQKEGSSEENLF SEDDLFYIIGDLFIAGTDTTTNSMLWSILYMSLYPDVQ EKVQKEIDAVVGSERVPSLTDKSSLPYTEATIMEVIRMTVVVPLSIPHMASETT EFRGFTIPKGTVIIPNLWSVHRDPTVWENPDDFNPSRFLDDQGKILRKDCFIPFGL GRRVCMGEQLAKMELFLMFTSLMQTFTFRFPEGATAPSMHGRFGLTLAPCPFTVCVKTR* >CYP2V1_Danre AB026158 zfishC-a1007a08.p1c zfishK-a1019e01.q1c MALENILLHLNSKVWTDAGTILLLFILFLLVSVKLRNRNKPTKT FLLGPTPLPFIGNVFNLDTSQPHICLTKMSDHYGNIFSLRLGSLNTVVVNTYSMVKKV LNDQGNSFMYRPSNDITERILSKCQGLTFNNGYSWKQHRRFTLSTLKFFGVGKRSLEF IIMEEYKFLHQSILDTNGLPFNPHYIINNGVSNIICSMVFGRRFEYTDQRFLNMLSLI SKALKLQTSVFIQLYAAFPRLMDLLPGPHKELFSCFHQVRAFIKEEVDKHRADWDPSS PRDFIDCYLTEIEKMKDDLEAGFHDEGLQYAVLDLFVAGTETTSTTLLWAFVYMMKYQ KSKKVQAEIDKVVGRYRRPSMDDRPCMPYTDAVIHEIQRMGNVVPLSVPRMTNEDTLL EGLFHSLRVLQIIPNLTSVLFDQTKWKTQHSFDPQNFLNAQGKLKSLKLLSPFSLGKR SCPGESLARMELFLFFTSFLQSFSLSAPDETQTSLDFKCGMTLSPKPFKICFTPR >CYP2X6_Danre ctg22265.a 66% to CYP2X1 MLGSSLLVVICILLIFFLIRVKKPKNFPPGPPPVPIFGNLLQLNLANPLKDFEK FAEKYGEIFSLYTGSRPAVILNSFAVIKEALVTKAQDFSGRPQDFMISHATENKGN IVLADYGPVLKGHRRFALMTMRNFGLGKQSMEERILGEISHVVDYLDKNA GKRVDPHIMFHNVASNVISLLLFGCRFDYNSEFLQCYIQLINEISKIINGPWNM IYDTFPLLRILPLPFKKAFDHVKVIKSMNLKLIDEHKSTRVPGEPRDFIDCYLDELDK GKNCVSTFSEDKLLMSIMDLHFAGTDTISNTLLTAFLYLMNHPEVQ VKCQQEIDDVLEGKDQVTYEDRHNMPYTLAVIHEVQRVANTVPLSVFHCTTRDTELMGYSIPK GTIIIPNLTRVLKEEGQWKFPYEFNPANFLNEQGQFEKPEAFIPFST GLRMCLGEGLARMELFLIFVTLLRRFQFVWPEDAGKPDYTPVFGLTLTPKPYRMHIRRRETVKQ* >CYP2X7_Danre ctg22265.b CYP2X1 Missing C-term CK030199 AI959373 BC053412 MLEVSVLILICIFLVFFLIRIKRPKNFPPGPPPVPIFGNLLQINMVDPLKEFER LAEKYGNIFSLYTGSKPAVFLNNFEVIKEALVTKAQDFSGRPQDLMISHL TGNKG VVLADYGPLWKDHRRFALMTLRNFGLGKQSMEERILGEISHIVDFLDKNT GKTVDPQIMFHNIASNVINLVLFGCRFDYNNEFLRGYIQRIAENLRILNGPWNM IYDTFPLLRILPLPFKKAFDNVKIIKSMNRKLIDEHKSTRVPGQPRDFIDCYLDELDK VKNCVST FSEDQLIMNIMDMSFAGTDTTSNTLLAAFLYLMNHPDVQ VKCQQEIDDVLEGKDQVTYEDRHNMPYTLAVIHEVQRVANIVPLSVLHCTTRDTELMGYSIPK GTVIIPNLTVVLKEEGQWKFPHEFNPANFLNEQGQFEKPEAFIPFST GPRVCLGEGLARMELFLIFVTLLRRF QFVWPEDAGKPDYTPVFGLTMTPKPYRMHIRRRNTVKQ >CYP2Y3_Danre ESTs CK016257, CK869788, CK706387, CB891035 NA1608 MELSSSLLLVLVLTVLMLIRWRRKENGLSLPPGPLALPLIGNLLTLDKSAPFKSFMK WRKTYGSVMTVHLGPQRMVVLVGYETVKEALVDQAEDFAPRAPIAFMNRIVKGY GLAISNGERWRQLRRFTLTTLRDFGMGRKQMEQWIQEESRYLLKSFEETK SKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQ LYNIFPQVMERFSSRHHAILKDVENIRTFIRNKVKEHEQRLDFSDPSDFIDCFLIRLTQ EKDKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQ EQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPK DTVIIPMLHSVLRDEGQWETPWTFNPEHFLDSNGNFKKNPAFMPFSA GKRSCVGESLARMELFLFTVSLLQKFTFSSPNGPDGIDLSPELSSFANMPRFYELIASPR* >CYP2AA1_Danre _AF497969 74% to 2AA2 MLVGLVKLDLASVGLTLFLGLIFLVLFEIFRINSYKFRFPPGPT PLPFVGNLPHFLKSPMEFIRSMPQYGEMTTIFFGRKPVIMLNTIQLAKEAYVQDAFSG RPAIPLFDWITNGLGIVMVTFNNSWRQQRRFALHTLRNFGLGKKTVEDRVLEESRYLI AEMLKEEGKSMNPQHALQNAISNIICSIVFGDRFEYDNKRFEYLLKTLNENIMLAGSA AGQIFNLVPFIKHFPGPHQKIKQNADELLGFIRDEAKEHKQTLDPDSPRDFIDAYLLE IEKQKSSKDSTFHEENLVVSASDLFLAGTDTTETTIRWGLINLIQNPDVQERCHEEIV RVLGYDRLPSMDDRDKLPYTLATVYEIQRCANIAPNVMHQTILPTRLHGYDIPQGTII LTNLAAIFSNKDHWKHPDAFNPENFLDENGHFSKPESFIPFSLGPRVCLGETLARTEL FLFITALLQRIRFSWPPDAKPIDMDGIMGLVRSPQTFNVVCHSRDNVK >CYP2AA2_Danre AI657973 fc19c11.y1, AI958603 fc94a10.y1, AI544967 fb69h12.y1 MFGALVKLDLSSVGLTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLRDPMGFNRL MAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQEAFAGRPCLPAIDWTSNGC GIIMATFNNSWKQQRRFALHTLRNFGLGKKSLESRVLEESQYLIAEMLKDE GRPMNPQHAVQNALSNIICSIVFGDRFDYNNKRFEYLLKILNESIILTGSAAGQ IFNFAPIIKHFPGPHQMINENANEVYSFVRHEVEEHRKTLDPGSPRDFIDGYLLEMEK QKSNKDSTFHEDNLITTTVDLFLAGSDSTSSSIRWGLLFLIQNPDVQ ERCHEEIVQVLGYDRLPCMDDRDRLPYTLATVHEIQRCGNIAPFGLFHETVQPTKLRGYNIPQ GTIIMTNYTAIFSNKEHWKHPDTFNPENFLDENGQFSKPKCFIAFGV GPRICLGDTLAKTALFLFITSLLQRIRFSLPPDAKPMDMDGILSIIRYPETFSIICCSRDTKE* >CYP2AA3v2 Danio rerio (zebrafish) ctg14330 (7 aa diffs MFTALLKLDLASVGLTLFLGLIILVLFEIFRIHSYKRRTPPGPTPLPFVGTIPHFLKNPLGFIRS MSQYGDMSTMYLGRKPAIFLNTIQLAKETLVQDTFSGKPYLPVIEWISKGF GIAMVTFNHSWRQQRRFALHTLKNFGLGKKSVEDRVLEESRYLIAEMLKDE GKPVDPHHPIQNAVSNIICSIVFGDRFEYNNKRFEYLLKMLNETIMLAGSASGR IFNLVPFIKHFPGPHQKIKKNTDDLLIFLGDEVEEHRKTLDPGSPRDFIDAYLLEIEK QKFNKDSTFHEGNLLASAGDLFMAGTDTTETTIRWGLLFLIQNPDVQ ERCHEEIVQVLGYDRLPSMDDRDRLPYTLATVHEIQRYGNIIPILIHETILPTKLQGYSIPQ GTTIVTNIQAIFSSKDHWKHPDSFNPENFLEDRHFIKPESFIMFSL GPRSCLGEILARTELFLFITSLLQRIHFSWPPDAKPIDMDGIFGLVHSPQAFNVICRSRDTK >CYP2AD2_Danre ctg24224.c AF248042, BC045948, NM_152954, AI497156 fb62g08.y MILHLIYDSFDFKSWIIFFVVFLIIAEMIKNRTPSNYPPGPWPLPFLGTVFTKMDFKNINK LAKVYGKVFSLRVGSEKMIIVSGYKMVKEALVTQNDSFVLRPPVPLFHKVYKGI GLTMSNGYIWRSHRRFAASHLRTFGEGKKNLELGIQQECVYLCDAFKAEK EPFNPIFILHGAVSNTVACLTFGQRFDYNDEWYQEILRLDNQCVQLAGSPRVQ LYNAFPKLLDYLPGPHQKVFSNYKKITQSLKDEIIKHREDWDPANPRDFIDNYLTEMEK KKSDPQAGFNIESLIISCLDIVEAGTETGATTLRWGLLFMIKFPEIQ EKVQAEIDRVIGQSRQPCLDDRVNMPYTEAVLHEIQRFGDVVPLGFPKQAAVDTKIGNYFIPK GTSITTNLSSVLHDPNEWETPDTFNPGHFLDKNGQFRKRDAFLPFSA GKRACVGELLARNVLFLFFTSLLQQFTLSKCPGEEPSLEGEIWFTYAPAPFRISVSVR >CYP2AE1_Danre chr23:39385089-39398315 (+) exon 9 corrected MSSVFSQLIGQWLDVQGFLIFLCVLLLVKHFRDVYSKNMPPGPFPLPFVGNLTNIGFSDP LGSFQR IAEKYGDVCTLYLGTKPCILMTGYDTLKEAFVEQADIFTDRPYFPIVDKLGN AGLIMSSGHMWRQQRRFALATLKYFGVGKKTLENAILQECRFLCDSLQAER GLPFDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGR LYNEFPTLMSLLPGKHQTAFASMSKLQPFLKEEITKHQQDREPSSPRDYIDCYLEEIEK QCKDSDAEFTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQ EKVQSEIDQVIGQTRQPLMDDRTNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPK GVIVLPMLKPILLDKKEYSTPYDFNPDHFLDQNGKFLKKENFIPFSI GKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQKLSLKGTTSVSSAPQPFQIRAVPR* >CYP3A65_Danre ESTs CF266016 CF999879 CF996069 CD014436 MFFSAETWTLLAFLVALLVI YGSWPHRYFKKLGIPGPKTIPFFGTMLRYKD GFHVFDMDCFEKYGRIWG IYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRR NFRLNGALYDAVSIAEDDDWRRIRSVLSPSFTSGRLKE MFGIMKKHSHILVDSMGKTAKRGESADIKE FFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLI AFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTK KRVDFLQLMVDSQTGVKHKSDGETHEK GLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQAPVD YETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEING LLIPKDLVVMVPTYVLHRDPDYWSEPESFKPER YETMMSMDYLDAALSESLRLYPVAARLERVCKKTVEING LLIPKDLVVMVPTYALHRDPDYWSEPESFKPER FTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQ VPLELGFNGLLSPKDPIKLKLQPRKLSQSPDVCNNNQKS* >CYP3C1_Danre NM_212673 AW076890, BF717373 fd45a03.y1 38092657-38099400 (-) MFDLSSLSVTWTLVVLVITLLLI YGVWPHGFFKKLGIPGPRPLPFVGTALSYSK GICNFDIECSKKYGKVWGIYDGRLPLLLVTDLEMIKTILVKDCYSTFT NRRNMNPDLVGPFADGITLVKDERWRRIRSSLSPYFTSGRLKEIFPIAMTHADRFIKN MEKKDPNLPLKIKDVVAPYSLDVVASSSFSVDFDSINNPDDPFVTSIKSFFNINPLSP LFLLLAFCPSAANLLAKMGISVFSRSTTDFYYKALRKIKDEHNESNGRVDFLKLMIQN QIPDDQVKDTASEQPVKGLTDHEILSQSFIFILGGYETTSTTLSYLLYNLATNPDCLE KLVEEIDKNFPLDIPITYDALMRMDYLEMAIHESMRVFPAGPRLERVCKKTVEINGIT IPKNTLVGIPLYVLSRDPDLWESPNEFKPERFSPESKTEINQCAFMPFGLGPRNCIGM RFALMMMKLLVVKLLQKYTVETCKETQIPVQLNFFFQPKVPITLKLIPRSHKEKQ >CYP4F43_Danre BG799227 (exons 1-4) NA16252 (exon 2) NA2909 (exons 3-12) MMLFGLSVTGILALSGAALLCALVTRIIINRRALRCFNQPPLRNWIMGHMGL MGHNEEGLQRVDDLVCKYGHSCSWFLGPFYNMVRLFHPDYIRSLLTAS ASITLKDRIFYGFMKPWL GNCLLLQSGQEWSRHRRLLTPAFHFDILKKYVHIFNQSTNIMH DEWRRLLASGEHSVDMFEQISSLTLDSLLKCTFSCDTHSQE KPRQYISAILDLSRLLVQRQHYLPYHWD WLYWRSAQGRRFQQACAVVHQFTADIVQERRTQLDQQSDPESHPENTGRYRKRKNTDLIDLLLLAK DDKGEALTNEEIKAHADMFMFA GHDTTASALSWIFYNLAMNQDYQERCRAEVRDLLADRDTHTIGW EDLSQLTFTTMCIKESLRLHSPVLALTRYYSQNMKTPGDCVIPH GCLCLISIYGVHRNPQVWPDPL VFDPTRFDPHNSDSRSPHAFIPFSAGPR NCIGQNFAMAEMKVVVALTLARFKILPGPKPVRRLYQLVLRAEGGMILHFQELNEE* >CYP4T8_Danre BC056734, NM_199216, CF943677 AI959112 fd24f08.y1 AI558878 MLLYGISPFVLSVNHVFALIFLACLLTVVKLLIVRRKGVKTMER FPGPPAHWLFGHVKEFRQDGHDLEKIVKWMELYQFAFPLWFGPSLAVLNIHHPSYAKT ILTTTEPKDDYAYKFFIPWLGDGLLVSTGQKWFRHRRLLTPGFHYDVLKPYVKLISDS TKVMLDKWEVHSRSEESFELFKHVSLMTLDSIMKCAFSCNSNCQTDSGTNPYIQAVFD LCHLVNLRFRVFPYHSKAIFHLSPHGYRFRKAASIAHNHTAEVIRKRKEVLKMEEEQG IVKNRRYLDFLDILLSARDEHQQGLSDEDIRAEVDTFMFEGHDTTASGISWIFYNLAC NPEHQEKCRQEIQQALDGKDTLEWEDLNKIPYTTMCIKESLRLHPPVPGISRKLTKPL TFFDGRTVPEGCTIGVSIYGIHMNSTVWENPYKFDPLRFLPENAANRSPHAFVPFSAG PRFVTRSV >CYP4V7_Danre ctg12974 69% to CYP4V 70% to 4V5 fugu, 70% to 4V6 396649 MGILFGLYILGILFTAVLLLLLASTAYNPLKNYIGKWNEMRPIPGMAGAYPIIGNALQFKTNAG DFFNQIIEGTNENRHLPLAKVWVGPVPFLILYHAENIE VVLSNSRHLDKSYSYRFLHPWLGTGLLT STGEKWRNRRKMLTPTFHFSILSDFLEVMNEQTDILIQKMQKLEDGEPFNCFNFITLCALDIIC ETAMGKKIYAQSNADSEYVQSVYK MSDIITKRQRAPWLWPDWIYNKLKEGKEHAKRLKILHSFTAN VIRERAEFMSSEPDSDSDQGGRKRQAFLDMLLKTTYENGQKLSHEDIQEEVDTFMFE GHDTTAASMNWALHLIGSHPEVQKAVQAELQEVF GSSERHVGVEDLKKLRYLECVIKESLRIFPSVPLFARSICEACHI DGFKVPKGVNAVIIPYALHRDPRYFPEPEEFQPERFMPENSKGRHPYAYIPFSAGPRNCI GQRFAMMEEKVVLATILRHFDVEACQSREELRPLGELILRPEKGIWIKLQRRSK* >CYP5A1_Danre AY398422 BG728082 BF718045 AW595283 MQLLVDGLKWFGVEASGLSLTVCLFLLFLSLLYWYSISPFSNLE RCGIKHPKPLPFIGNLMMFRNGFFKSQADLINKYGRICGYYIGRRSTVIIADPDMLRQ VMVKEFNKFPNRMTARGITKPMSDSLIMLKGEQWKRVRSILTPTFSAAKMKEMVPLIN TATETLLRNLKSHAESENSFNIHKCFGCFTMDVIASVAFGTQVDSQNNPDDPFVHQAS KFFAFSFFRPIMIFFMAFPFLLRPLAGLLPNKSRDEMNSFFTQCIQKMIKQRDDLSPE QRRKDFLQLMLDVRTNNKFLSVEHFDVVNDADEEAYDGHENSPANESTKRSQQKRMMT EDEIVGQSFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHEMVDYAN VQELKYLDMVICESLRLYPPAFRVARDVEEDTVLNGQFLPKGASLEIPTGFLHYDPEH WTEPTKFIPERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNV LACEDTEIPLELKSHTTLGPKNGVMVKITERENLEDAS >CYP7A1_Danre BC054571 BF718169 fd57d07.y1 BF717505 fd45f11.y1 MILTISFIWAIVVGLCCCLWLITGIRRRHPAEPPLENGWIPFLG CALQFGANPLEFLRSRQKKHGHIFTCKIAGQYVHFLCDPFSYHAVIRQGRHLDWKKFH FDASAKAFGHESMDPSQGYTTENLHQTFLKTLQGDALSSLIETMMENLQGTMLQSGML KATTSEWQSDGIYAFCYKVMFEAGYLTLFGKELDGDQSIARQQAQKALVLNALDNFKE FDKIFPALIAGLPIHVFKSAYSAREKLAKTMLHENLSRRANVSDLISLRMLLNDTLST FNELSKARTHVAILWASQANTLPATFWTLFHMIRCPAAMKAASEEVRQTFESSNQKVD PTNSRLVLTREQLDNMPVLDSIIKEAMRLSSASLNVRMAKSDFLLQLDNKESYHIRKD DVIAMYPPMIHFDPEIYDDPLEFKYDRYIDEKGQEKTAFYRNGRKLRYYYMPFGSGVT KCPGRFFAVHEIKQFLSLLLSYFEMELLDSDVKEPPLDQSRAGLGVLQPTYDVDFRYR LKSL >CYP7C1_Danre 51% TO 71C1 FUGU ctg22254 BI473289 fp42a01.y3 MLEYLLTILLGFISVLLLYSFCGRRR KDGEPPLIKGWIPFLGKALEFRKNSQEFLTRLQKEHGDDFTVL CVSLGRYITFIMNPLQYPSVIKHGKQLDFHTFSDSAASRTFDYPPIRSGHFPGLSDQIQR SYTLLQGPALDPLTFSMMGNLQKVLRQLFLSGDEADDHWQQAELYKFCKSAMFQSTFKT LYGHSPHLDLDQLREDFEKFDDMFPLLMARIPIGLLGKTKEIREKLIHFFYPQRMM EWTAPCEFVQTRTALFQDYDTLQDRDKA AHHFAMLWASVGNTIPAALWCLYHLISCLEALAAVREEITNVLGEKNMQLIFKEDIAITR QQLEQMVYL ESSVNESLRLYSVSMNIRVVQEDFCLRLDGQRSINMRKDDIIALYPQSTHLDPEIYKEPK FQFDRFVKDGKEKTDFYKSGQKVRYYRMPFGSGATQCPGRFFAMNELKQFVCVTLLMCEM QLLDGQQEASMDNSRAGLGILPPANPIPFKYKTR >CYP7D1_Danre BG883457 fp29f09.x1 381-502 54% to 7A Z35725-a6349d05.p1c MLIITVFVCRKPGEPPLVTGWLPFIGVTKDYVSNPLGFLTETQKKHGNVFTCLIAGKYFTFV TDPFSFSSVVRQGKNLDFQKFAINFSQR VFGHADFNSPQLSGNYREIHSIFRQTLQGPSLQHLTQSMLCNLQTVLERCLPHEH DWLEEGVQSFTNRIMFEAGFLTLFGKEDIRFLQDHGMSGNRISMPKATQDFLVFDHAFPL LAAGVPIGLCTKAWRAREALAEELLHDELHRRKCISDLIQRRMDIFDRMLLDETGKART DVCMLWASQANTLPAAFWSLYYTLK SVDAFTAARTEVNRVLLGQSLNNKDQTVYLSKDQLDSMTVL ESIIEEALRLSSASMMIRVASDDFTLTLESDQTAAIRKGDYIALYPQLLHLDPEIYPNPT EFKYNRFLDENDQPKTNFFKSGRRLRNFLMPFGSG ASECPGRFFAVYEIKLFLALTLWHYDLQLRDPDVPVVQDSARAGLGIMPPSQDVLLRFR KKQRTPGNEHKDTK* >CYP8A1_Danre BX546446.15 02-SEP-2004 clone DKEY-7K24 in linkage group 6 MMWTALLLVGLSILVIVLYGRRTR RRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFT VRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEM HFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFK TGYLTVFGAENNDSAALTQIYEEFRRFDKLLPKLARTTINK EEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQ GNAGPAAFWVMGYLLTHPEALRAVREEIQGGKHLRLEERQKNTPVF DSVLWETLRLTAAALITRDVTQDKKIRLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPE MFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKE LVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIRF* >CYP8B1_Danre 68% to 8B1 fugu 91% to CYP8B.b AI558624 chr2:2632344-2633870 (-) MALVQILLALLISVIGALYLLGSFRRRRTGEPPLEKGPIPWLGHVLEFRKDTAKFLNRMKA KHGDIFTVQLGGFYFTFITDPLSFGAVVKEARAKLDFTKFAEQLVQRVFGYHSIQSEHKV LQASSTKHLMGDGLVVMTQAMMYNLQNLMLHSVGSGNGKVWQESGLFAYSYNIVFRAGY LSLFGNESPKGTGKESVEKAKEIDRQESNDLFWEFRKYDQLFPNLAYGVLGPSEKMEAER LKRLFWSTLSVQKMRARDNISGWVSDQQQVRAEHGMQEFMQDRYMFLLLWASQGNTGPSA FWLLLYLMKHPEAMSAVRKEVEEILKEAGQEVKPGGPLIDLSRDMLLKTPILDSAVEETL RLTAAPILTRAVMQDMTIIMANGQEYKIREGDRVAVFPYVVHVDPEVHPDPLTFKYDRF LNADGSRKTDFYKGGKKLKYYSMPWGAGTTMCPGRFFATNELKQFVFLMLSYFDFELTNP NEQIPGIDIRRWGFGSMQPDRDIQFRYRPRI* >CYP11A1_Danre BC054701 MARWNVTFARLDQSLSSLKNLLQVKVTRSGRAPQNSTVQPFNKI PGRWRNSLLSVLAFTKMGGLRNVHRIMVHNFKTFGPIYREKVGIYDSVYIIKPEDGAI LFKAEGHHPNRINVDAWTAYRDYRNQKYGVLLKEGKAWKTDRMILNKELLLPKLQGTF VPLLEEVGQDFVARVNKQIERSGQKQWTTDLTHDLFKFSLESVSAVLYGERLGLLLDN IDPEFQHFIDCVSVMFKTTSPMLYLPPGLLRSIGSNIWKNHVEAWDGIFNQADRYIQN IFKQWKENPEGNGKYPGVLAILLMQDKLSIEDIKASVTELMAGGVDSVTFTLLWTLYE LARQPDLQDELRAEISAARIAFKGDMVQMVKMIPLLKAALKETLRLHPVAMSLPRFIT EDTVIQNYHIPAGTLVQLGVYAMGRDHQFFPKPEQYCPSRWISSKRQYFKSLGFGFGP RQCLGRRIAETEMQIFLIHMLENFRIEKQKQIEVRSKFELLLMPEKPIMLTIKPLNASR >CYP11B1_Danre 70% to Fugu 11B1 BI880530 AL916948 Z35724-a4708b08.q1c MFSSCAGSVCARPHLCVRASVCVRPLHQSSRSA GAARLFQEIPDTGSNGWMNLLRFWRDGRFSRMHKHMEESFRRLGPIYR EHLGSQSSVNIMLPMDTGELFRSEGLHPRRMTLQPWATHRETRRHSKGVFLK NGTEWRADRLLLNREVMVSSSVHRFLPLLDEVAQDF CRSLRRRVQADGFEKAGQHTLTLDPSPDLFRFALE ASCHVLYGERIGLFSSCPSDESERFISAVERMLATTP PLLYLPPRLLLRLRASLWTTHATAWDDIFSH AEQRIQRSYQRLQARASAAPDCSFPGVLGKLMEAGQLSLELIQIHITELMAGGVDT TAVPLQFALFELARNPDVQECVRAQVLSSWRQASGDPLNALQGAPLLKGTLKETLR LYPVGITVQRYPVRDIVLQNYHVPAG TLVQVCLYPLGRSAEVFSRPECFDPSRWSADADAGSAGGFRSLAFGFGSRQCVGRRI AENEMQLLLMH ILRTFKLTVSSTEELSTKYTLILQPECPPRITFSTLTHQH* >CYP17A1_Danre NM_212806 NM_201173 AI883222 fd17f05.y1 MAEALILPWLLCLSLFSAVTLAALYLKQKMNGFVPAGNRSPPSL PSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKK GKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIIC REASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAELESMLQYSRGI VDTVAKDSLVDIFPW LQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLL DALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAGVETTTTVLKWSIAYLVHNPQ VQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRIRPVSPLLIPHVALQDSS V GEYTVQKGTRVVINLWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGV RVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVRA DWEKSPLMQHC >CYP19A1_Danre = 19a AF183906 AF004521 AF226620 AF183907 (alt splice) ovarian MAGDLLQPCGMKPVRLGEAVVDLLIQRAHNGTERAQDNACGATA TILLLLLCLLLAIRHHRPHKSHIPGPSFFFGLGPIVSYCRFIWSGIGTASNYYNSKYG DIVRVWINGEETLILNRSSAVYHVLRKSLYTSRFGSKLGLQCIGMHEQGIIFNSNVAL WKKVRAFYAKALTGPGLQRTMEICTTSTNSHLDDLSQLTDAQGQLDILNLLRCIVVDV SNRLFLGVPLNEHDLLQKIHKYFDTWQTVLIKPDVYFRLDWLHKKHKRDAQELQDAIT ALIEQKKVQLAHAEKLDHLDFTAELIFAQSHGELSAENVRQCVLEMVIAAPDTLSISL FFMLLLLKQNPDVELKILQEMDSVLAGQSLQHSHLSKLQILESFINESLRFHPVVDFT MRRALDDDVIEGYNVKKGTNIILNVGRMHRSEFFSKPNQFSLDNFQKNVPSRFFQPFG SGPRSCVGKHIAMVMMKSILVALLSRFSVCPMKACTVENIPQTNNLSQQPVEEPSSLS VQLILRNTL >CYP20A1_Danre Danio rerio (zebrafish) ctg10765 74% to fugu MLDFAIFAVTFVIILIGAVLYLYP SSRRASGVPGLNPTEEK DGNLQDIVNKGSLPEFLVGLH DEFGSVASFWFGARPVVSLGAVNQLRQHINPNWT TDSFETMLKSLLGYQSGSGVGLTESMMRKKVYEGAINKTLENNFPLLLQ QVEELVDKWASYPKSQHTPLCAHFL GLAMKAVTQLAMGSRFRDDAEVIRFRKNHEA IWSEIGKGYLDGSLEKSSSRKAHYES ALAEMESVLKSVAKQRPGQGSSQSFVNYLLQANLTERQ VMEDGMVFTLAGCVITAN LCIWAVHFLSVSEAVQDRLYHELVEVLGDELVSLEKIPQLR YCQQVLNETVRTAKLTPVAARLQEVEGKVDQHVIPKE TLVIYALGVVLQDADTWSLPYR FNPDRFAEESVMKSFSLLGFSGSQACPELR FAYTVATVLLSTLVRRLRMHRVDGQVVEARYELVTTPKDDTWITVSKRN* >CYP21A1_Danre AL953915.4 Zebrafish exon 7 boundaries not certain, MCFSVVSVVLLLFILWMLVVKFWRQSHRRTDG IVILICVSFYCPIAVFPKLLHSLYKLFFSTVSPTISGPRSL PLLGNMLDLAQDHLPIHLTALA KCYGNIYRLNCGSTS 5738 AMVVLNNSEIIREALVKKWSDFAGRPYSYTG XDIVSGGGRTISLGDFSEEWKAHRRVTHSALQRCTTDSLHSVIEKQAQHLCQ VLRDYSGKAVDLSEDFTVASSNVITTLTFSKA YDKSSAELQKLQECLNEIVSLWGSPWISALDSFPLLR KFPNPPFSRLMKEVARRDELIGKHIEEFK KSEHKEGGTLTSSLLKCLEPQQGAANHT TLTDTHVHMTTVDLLIGGTETIAALLNWTVAFLLHRPE VQDKVYEELCCVLDVRYPQYSDRHKLPYLCALISEMLRLRPVAPLAVPHRAIRNS SIAGHFIPKNTIIIPNLYGAHHDPEVWDDPYSFKP ERFLEGGGGSLRSLIPFGGGARLCLGEAVAKMEMFLFTAYLLREFKFLPASKEEPLP ELRGVASVVLKVKPYTVIAHPREQ* >CYP24A1_Danre ctg12249 CN507760.1 69% to human CYP24 76% to fugu CYP24 MRAHLQRAPQILELLKKKTAGLQHCKPTSSVCVLDSKDAAGSAPCAHS LDSIPGPTNWPLFGSLIEVIRNGGLKRQHETL IHFHKKFGKIFRMKLGSFESVHIGSPCLLEALYRKEGSYPERLEIKPWKAYRDMRDEAYGLLIL SEVAADLIKRIGKVNGKMDDLYFELNKWSFET ICYVIYDKRFGLLQDSVSKEGMDFITAVKT MMSTFGTMMVTPVELHKTLNTKTWKDHTEAWDRIFST AKHYIDKNLQKQSNGEADDFLSDIFHNGNLTKKELYAATTELQVGGVET TANSMLWVIFNLSRNPCAQGKLLKEIQDVVPAGQTPRAEHIKNMPYLKACLKESMR VSPSVPFTSRTLDKDTVLGDYTLPKG TVLMLNSQAIGVSEEYFDNGRQFRPERWLEEKSSINPFAH VPFGVGKRMCIGRRLAELQIQLGLCWILRDYK IVATDLEPVDSLHSGTLVPSRELPVAFVPR >CYP26A1_Danre U68234 MGLYTLMVTFLCTIVLPVLLFLAAVKLWEMLMIRRVDPNCRSPL PPGTMGLPFIGETLQLILQRRKFLRMKRQKYGCIYKTHLFGNPTVRVMGADNVRQILL GEHKLVSVQWPASVRTILGSDTLSNVHGVQHKNKKKAIMRAFSRDALEHYIPVIQQEV KSAIQEWLQKDSCVLVYPEMKKLMFRIAMRILLGFEPEQIKTDEQELVEAFEEMIKNL FSLPIDVPFSGLYRGLRARNFIHSKIEENIRKKIQDDDNENEQKYKDALQLLIENSRR SDEPFSLQAMKEAATELLFGGHETTASTATSLVMFLGLNTEVVQKVREEVQEKVEMGM YTPGKGLSMELLDQLKYTGCVIKETLRINPPVPGGFRVALKTFELNGYQIPKGWNVIY SICDTHDVADVFPNKEEFQPERFMSKGLEDGSRFNYIPFGGGSRMCVGKEFAKVLLKI FLVELTQHCNWILSNGPPTMKTGPTIYPVDNLPTKFTSYVRN >CYP26B1_Danre NM_212666 87% to fugu 26B1 AI721901 fc26h10.y1, MLFESFDLVSALATLAACLVSMALLLAVSQQLWQLRWTATRDKS CKLPMPKGSMGFPIIGETCHWFFQGAGFHASRRQKYGNVFKTHLLGRPLIRVTGAENV RKVLMGEHSLVTVDWPQSTSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPK IQQVIQETLRVWSSNPDPINVYRESQRLSFNMAVRVLLGFRIPEEEMHCLFSTFQEFV ENVFSLPIDLPFSGYRKGIRARDSLQKSIEKAIREKPLHTQGKDYTDALDVLLESAKE NNTELTMQELKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHD GCLCQGELRLDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDGVQVPKGWSVM YSIRDTHDTSAVFKDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFL KLLAVELAGGSRFELSTRTFPRMISVPVVHPTDGLRVKFFGLDSNQNQIMAKSDEMLD ATV >CYP26C1_Danre ctg13279 ZEBRAFISH EXON 5 HIGHLY VARAIBLE IN LENGTH MFDHGFCLVSALLSVADAVLPTVLLLAVSRLLWEFRWSITRDKTCKLPLPQGSMGWPLVGETFHWLFQ GSSFHISRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQWPQSTRIILGP NTLVNSVGDLHKRKRK VLAKVFSRGAQ*APFIRLQDVVEFDIAKWCNKTGFVEVTSAAESLTFRITVGVVLGMHLK DQQITYLSKALEQLMNNLFSLPIDTPVSGLRK GIRAREILHSAMEKIIEEKLKKQQASDYCDAFDYMLSSARENDYELTMQELK SPAVELIFAAHSTTASASTSLIMQLLRHPDVSERARAELESEGL ITDGHGHCRSRCNGNEEGEAAEKSTSDRRSAINKATYFEAGDKEEGR RSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTFELN GYQIPKGWSVMYSIRDTHETAEAYQNPEFFDPDRFCVGREESKSERFSYVPFGGGVRR CIGRELALIVLKTLAVELLATADCTLATQTYPRMQTVPIVHPVNGLHVFFNYR TQGIERNRRESTHI* >CYP27A3_Danre _ctg11505 EST = CD283382 chr9:22363585-22376631 (+) MFSNSLLRTGLFLCKQDCSGIKCLTSMFLNARTTSTLIGGDKQKTMDDLDGPS FLTSLYWLFGKGYFQTTHQMQIEHSKIYGPLWKSKYGPLVIVNVASAHLIKQVLRQ EGRHPIRTDMPHWRGYRKLRNHAYGPLTEM GPEWQRIRSILNPRMLKPKHVSNYTNAINGVVSDFIEKMAKLKTTKGNDVMVYDVAGELYKFAFE GISSVLFETRMGCLNDEIPEETQKFIFSVGEMFRLSPIVILFPKFLWPYMPF WKHFVAVWDHLFKV ADELVQQKMTEIQEKVKTGSPVEGEYLTHLLISEQMSFTEVLGSITELLLAGVDTVSI TISWALYHLAREPEIQQKLHEEVVSVCPGDKTPSSDDITRMPLLKAIVRETLR LYPVVPANARVVAQNEIVVGDHLFPK QTLFHLCHFAVSYDETVFPDPFAFLPQRWIREQKQLSQH PFGSVPFGFGIRACLGRRVAELEMYLLLSR LIKRYEVRPDPSGKTVKPITRTLLVPATSIDLQFIDR* >CYP27B1_Danre ctg10726 72% TO 27B1 FUGU from multiple contigs MMMVLHQALKVTGRSALPLLRFAERWADVIRAPPTPQVKTLEQMPGPSPARFIRDLFMKRGFS RLHQLQ LEGRQKYGPMWKASFGPILTVHVAEPELIQQVLRQEGQHPMRSELSSWKDYRALRGEG YGLLT SEGEEWQCVRSLLSKHMLRPQAVEAYDGALNAVVSDLLQKLKLRSQESSSRIVSDISAEF YRFGLEG ISSVLFESRIGCLDAVVPVETERFIQSINTMFVMTLLTMAMPQWLHRLLPKPWDTFC RCWDVMFEF AKGHIDQRLQQEKQKLECGEQLEGRYLTYFLSQAGLPLTSVYSNVTELLLAGVDT ISSTLSWSLYELSRHPDVQTALRXEVLSVMKGRRSVPQASDVAAMPLLKAVVKEIL RLYPVIPANARVINKDIEVGGYVIPKN TLITLCHYATSRDP QQFRDPDSFRPQRWGDRSDRSHPYATVPFGVGKRSCIGRRIAELEVYLALSR ILMHFTVEPARQDDTVHPMTRTLLVPERQIDLRFTER* >CYP27C1_Danre ctg14633 70% TO FUGU CYP27C1 MARKNLLQESCRQLLIQTHGLHKSVASGSLEIAAHSQADLKEESAVSPAEEVQ KAARVKSLKEMPGPSTVANLLEFFYRDGFSRIHEIQ MEHAKKYGKIFKSRFGPQFVVSIADRDMVAQV LRSESATPQRGNMESWKEYRDLRGRSTGLISA EGDEWLKMRSVLRQLIMRPRDVAVFSSDVT DVVADLVKRVKTLRSQQDDSQTVLNINDLFFKYAME GVATILYETRLGCLENEIPKMSQEYITALHLMFSSFKTTMYAGAIPKW LRPIIPKPWEEFCSSWDGLFKFS IHVDKRLSEIKKQMEKSEEIKGGLLTHMLVTREMNLEEIYANMTEMLLAGVDT TSFTLSWSTYLLARHPTIQQQIFEEVDRVLGGRVPTGEDVPYLPLIRGLVKETLR LFPVLPGNGRVTHDDLIVGGYLIPKG TQLALCHYSTSMDEENFPRPEEFRPDRWIRKDASDRVDNFGSIPFGYGIRSCVGRRIAEL EMHLALTQ LLQNFHIEVSPQTTEVHAKTHGLLCPGASINLRFTDRK* >CYP39A1_Danre ctg9833 48% to 39A1 AL929058.4 96727-71438 MEWITLILTVSVVIISFHLLFGKSHPNAPPCIRGWIPWFGAAFEFGKAPLHFIQQARAK YGPVFTVVAAGKRMTFVTLNEDFRVFFTSKDVDFEQAVQEPVHNT ASISKDNFFESHPTCSAIIKGRLTPGNTAMLSPHLCEEFNDHLESLGSEGSGQLNELIK SVMYPSVMSNLLGRCNSPSSALSRQEFLEKFTTYDEGFEYGSQLPEMFLK EWSNSKHWLLSL LRKMVIKSEETLYSESDRK TLLQHLAASISEQYLPNYGLLLLWASLANAIP VTFWAVAFILSNPTAYKIVMDQINSVLGRQG KQKTKVTLDDLQQMPYVKWCIMEAIRLRAPGAITRKVVRPLKLX NYVIPPGDMLMLSPYWAHRNPKYFPDPEDFKP ERWETADLEKNVLLEGFVAFGGGKNQCPGR WYAIMELHMFVALILYKFEFAQLDPMPK >CYP46A1_Danre chr20:4947279-4961022 (+) XM_001331518.2 (8 aa DIFFS) BC109436.1 MIFEWVLYIVFSLLAAVFTAFLGYCLYIHHLHQKYDHIPGPPRD SFLLGHSSSLTKAVYSDNNLIHDLFLYW AEKYGPVYRINTLHYVTIVVYCPEATK TIMMSPKYTKDPFVYRRVFNLFGKR FLGYGLITAVDHDIWYRQRRIMDPAFSSS YLRSLISTFDEMSERLMDKLEEIANNKTPAVMHDLVNCVTLDVICK VAFGVDLNFLTQKDSPFQNAVELCLKGMTFDVRDPLFR IIPKNWKLIQQVREATELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAGM QNVTSTEDFEQMLDNFVTFFMA GQETTANQLSFAIMELGRNPEIYKR AKAEVDEVLGTKREISNEDLGKLTYLSQ VLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVM FSSYVSQRLEKFFKDPLKFDPERFDVNAPK PYYTYYPLALGPRTCIGQVFSQ MEAKLVLAKLLQRFEFSLVPGQSFDIKDNGTLRPKSGVICNIKQCS* >CYP51A1_Danre AY496939 MTILEVGSQLIESAVLQMSLTSVLLTASVFTLTLGYISKLLFTQ HSSEHTKYPPHIPSSLPFLGQAVAFGRSPIEFLEKAYEQYGPVVSFTMVGKTFTYLLG SDAAALMFNSKNEDLNAEDVYARLTTPVFGKGVAYDVPNPLFLEQKKMLKTGLNIAQF KQHVEIIEEETKDYFRRWGESGERNLFDALSELIILTASRCLHGCEIRSLLDERVAQL YADLDGGFTHAAWLLPGWLPLPSFRRRDRAHLEIKKIFYNVIKKRREDTEKHDDILQT LIDATYKDGRPLSDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQK SVCGEELPPLHYDQLKDLSLLDRCLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQ VCVSPTVNHRLQDTWAERLDFDPDRYLHDNPAAGEKFAYIPFGAGRHRCIGENFAYVQ IKTIWSTLLRMFDFELVDGHFPPVNYTTMIHTPHNPIIRYTRRNAQPQQ >CYP1_Mmus NP_034123.1 cytochrome P450 1A2 [Mus musculus] MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIG STPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYL EEHVSKEANHLVSKLQKAMAEVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPV LRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLIPEEKIVNIVNDIFGAGFDTV TTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIP KERCIYINQWQVNHDEKQWKDPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFS VPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK >CYP2E1_Mmus MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKLAKRFGPVFTL HLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGK QGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLL STPWIQAYNYFSDYLQYLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQ EPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYM DAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGSIPREFKLCVI PRS >CYP4X1_Mmus MEASWLETRWARPLHLALVFCLALVLMQAMKLYLRRQRLLRDLSPFPGPPAHWLLGHQKFLQEDNMETLD EIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQHRCLL TPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYE SYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEKIIQDRKKILKNQVKQDDTQT SQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD GSSITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWND PKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLTRPPAFSSHTV LRPKHGIYLHLKKLLEC >CYP11A1_Mmus MLAKGLSLRSVLVKGCQPFLSPTWQGPVLSTGKGAGTSTSSPRSFNEIPSPGDNGWLNLYHFWRESGTQK IHYHQMQSFQKYGPIYREKLGTLESVYIVDPKDASILFSCEGPNPERFLVPPWVAYHQYYQRPIGVLFKS SDAWKKDRIVLNQEVMAPGAIKNFVPLLEGVAQDFIKVLHRRIKQQNSGNFSGVISDDLFRFSFESISSV IFGERMGMLEEIVDPEAQRFINAVYQMFHTSVPMLNLPPDFFRLLRTKTWKDHAAAWDVIFNKADEYTQN FYWDLRQKRDFSQYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRA EVLAARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYTVNDLVLRNYKIPAKTLVQVASFAMGR DPGFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEVQNLRDVG TKFSLILMPENPILFNFQPLKQDLGPAVTRKDNTVN >CYP17_Mmus MWELVGLLLLILAYFFWPKSKTPNAKFPRSLPFLPLVGSLPFLPRRGHMHANFFKLQEKYGPIYSLRLGT TTAVIVGHYQLAREVLVKKGKEFSGRPQMVTLGLLSDQGKGVAFADSSSSWQLHRKLVFSTFSLFRDDQK LEKMICQEANSLCDLILTYDGESRDLSTLIFKSVINIICTICFNISFENKDPILTTIQTFTEGIVDVLGH SDLVDIFPWLKIFPNKNLEMIKEHTKIREKTLVEMFEKCKEKFNSESLSSLTDILIQAKMNAENNNTGEG QDPSVFSDKHILVTVGDIFGAGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLL MLEATIREVLRIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDRFMPERFLDPT GSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRFDFDVSDDKQLPCLVGDPKVVFLIDPFKV KITVRQAWKDAQVEVST >CYP21_Mmus MLLPGLLLLLLLLAGTRWLWGQWKLRKLHLPPLAPGFLHFLQPNLPIYLLGLTQKLGPIY RIRLGMQDVVVLNSNRTIEEALIQKWVDFAGRPHMLNGKMDLDLSLGDYSLMWKAHKKLS RSALMLGMRDSMEPLIEQLTQEFCERMRAQAGTPVAIHKEFSFLTCSIISCLTFGDKDST LVQTLHDCVQDLLQAWNHWSIQILTIIPLLRFLPNPGLQKLKQIQESRDHIVKQQLKQHK DSLVAGQWKDMIDYMLQGVEKQRDGKDEERLHEGHVHMSVVDLFIGGTETTATTLSWAVA FLLHHPEIQKRLQEELDLKLGPGSQLLYRNRMQLPLLMATIAEVLRLRPVVPLALPHRAT RASSISGYDIPKDMVIIPNIQGANLDEMVWELPSKFWPDRFLEPGKNPRTPSFGCGARVC LGEPLARLELFVVLARLLQAFTLLPPPDGTLPSLQPQPYAGINLPIPPFQVRLQPRNLAP QDQGERP >CYP24A1_Mmus MSCPIDKRRPLIAFLRRLRDLGQPPRSVTSKAHVKRAPKEVPLCPLMTDGETRNVTSLPGPTNWPLLGSL LEIFWKGGLKKQHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEALYRTESAHPQRLEIKPWKAYRDH RNEAYGLMILEGQEWQRVRSAFQKKLMKPVEIMKLDKKINEVLADFMGQIDELRDERGRIQDLYSELNKW SFESICLVLYEKRFGLLQKDTEEEALTFIAAIKTMMSTFGKMMVTPVELHKRLNTKVWQAHTLAWDTIFK SVKPCIDHRLERYSQQPGADFLCDIYQQDHLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQ RLLREIQSVLPDNQTPRAEDVRNMPYLKACLKESMRLTPSVPFTTRTLDKPTVLGEYTLPKGTVLTLNTQ VLGSSEDNFEDADKFRPERWLEKEKKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDS EPVEMLHLGILVPSRELPIAFCPR >CYP27A1_Mmus MAAWSRTRLRWTLLDPRVVGRGLCPQGARAKATIPAALQAQESTEGPGTGQDRPRLRSPAELPGTGTLQF LFQLFLQGYVLHLPDLQVLNKTKYGPMWTTSFGTYTNVNLASAPLLEQVMRQEGKYPIRDHMDQWKDHRD HKGLTYGIFIAQGEQWYHLRQALKQRLLKPDEAALYTDALNEVISDFITRLDQVRAESESGDQVPDMAHL LYHLALEAITYILFEKRIGCLKPSIPEDTAAFIRSVAIMFQNSVYITFLPKWNRPLLPFWKRYLNGWDNI FSFGKKLIDEKVQELKAQLQETGPDGVRVSGYLHFLLTNELLSTQETIGTFPELLLAGVDTTSNTLTWAL YHLSKSPEIQEALHKEVTGVVPFGKVPQHKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFL FPKNTQFVLCHYVVSRDPSVFPEPNSFQPHRWLRKKEADNPGILHPFGSVPFGYGVRSCLGRRIAELEMQ LMLSRLVQKYEIALAPGMGEVKTVSRIVLVPSKKVRLHFLQRQ >CYP46_Mmus MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVLQDVFLDWAKK YGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDYGRWYKQRKV MDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKP LSQAVKVMLEGISASRNTLAKFMPGKRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDVPADILTQIL KAEEGAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRL QYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA PKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRG WQPAPPPPPC >CYP11A1_Ggal MLSRAAPIAGSFQACRCAGGIPALAGVHYPLPSSSGARPFDQVPGEWRAGWLNLYHFWKEGGFHNVHNIM ASKFQRFGPIYREKLGVYESVNIISPRDAATLFKSEGMLPERFSVPPWVAYRDYRNKPYGVLLKTGEAWR SDRLTLNKEVLSPQVVDSFVPLLDQVSQDFLRRARAQVQQSGRERWTADFSHELFRFALESVCHVLYGER LGLLQDFVDPEAQQFIDAVTLMFHTTSPMLYVPPALLRHLNTKTWRDHVHAWDAIFTQADKCIQNVYRDI RLQRKSTEEHTGILFSLLVQDKLPLDDIKASVTEMMAGGVDTTSMTLQWAMLELARSPGIQERLRAEVLA AKQEAQGDRVKMLKSIRLLKAAIKETLRLHPVAVTLQRYTTQEVILQDYRIPPKTLVQVGLYAMGRDPEV FPKPEQFNPERWLVMGSKHFKGLSFGFGPRQCLGRRIAELEMQLFLMHILENFKIETKRAVEVGTKFDLI LVPEKPIYLRLRPLQPQE >CYP17_Ggal gi|50053695|ref|NP_001001901.1| steroid 17-alpha-hydroxylase/17,20 lyase precursor [Gallus gallus] MPPLAVLLLALALLCAWRLSYSQGPTGTGTGRPRSLPALPLVGSLLQLAGHPQLHLRLWRLQGRYGSLYGLWMGSHYVVV VNSYQHAREVLLKKGKAFAGRPRTVTTDLLSRGGKDIAFASYGPLWKFQRKLVHAALSMFGEGSVALEKIICREAASLCE TLGAAQDMALDMAPELTRAVTNVVCSLCFNSSYRRGDPEFEAMLEYSQGIVDTVAKESLVDIFPWLQIFPNRDLALLKRC LKVRDQLLQQKFTEHKEAFCGDTVRDLMDALLQVRLNAENNSPLEPGLELTDDHLLMTVGDIFGAGVETTTTVLKWAVLY LLHYPEVQKKIQEEMDQKIGLARHPHLSDRPLLPYLEATISEGLRIRPVSPLLIPHVSLADTSIGEYSIPKGARVVINLW SVHHDEKEWDKPEEFNPGRFLDEQGQHIHSPSPSYLPFGAGIRVCLGEVLAKMELFLFLAWVLQRFTLECPQDQPLPSLE GKFGVVLQVQKFRVKARLREAWRGEMVR >CYP17_Xlae gi|285026523|ref|NP_001090540.2| cytochrome P450 family 17 subfamily A member 1 [Xenopus laevis] MISYVAGALLLAFGLALISVWKFAGGKHRGAKYPNSLPCLPFIGSLLHIGNHLPPHILFCKLQEKYGSLYSFRMGSHYIV IVNHHEHAKEVLLKKGKTFGGRPRAVTTDILTRNAKDIAFANYSPSWKFHRKVVHAALSMFGEGTVAIEKIISREATSLC QSLISFQDNPLDMAPELTRAVTNVVCALCFNTRYKRCDPEFEEMLAYSKGIVDTVAKDSLVDIFPWLQIFPNKDLDILKR SVAIRDKLLQKKLKEHKEAFCNEEVNDLLDALLKAKLSMENNNSNISQEVGLTDDHLLMTVGDIFVAGVETTTTVLKWTM AYLLHYPEVQTKIQEELDFKVGFGRHPVLSDRRILPYLDATISEVLRIRPVAPLLIPHVALQESSIAEYTIPQDARVVIN LWSLHHDPNEWENPEEFNPERFLDENGNHVYSPSQSYLPFGAGIRVCLGEALAKMEVFLFLSWILQRFTLELPAGDSLPD LDGKFGVVLQVKKFRVTTKLREAWKNIDLTT >CYP27B1_Xlae MAQTLKLGSSRSSQLFRGLQELWAETVLKNSEKVIKGHKSLADMPGPSTVSFISDLFCRRGLARLHELQL EGKAKFGPVWKASFGPILTVHVAEPSLIEQVLRQEGKHPIRSDLSSWKDYRQCRGHSYGLLTAEGEEWQQ FRSILGKHMLKPKEVEAYSDVLNDVVGDLIKKINYQRSQNQNNVVKDIAKEFYMFGLEGISSVLFESRIG CLEPTVPKETEKFIQSINTMFVMTLLTMAMPKFLHKIFRKPWQKFCESWDYMFAFAKGHIDKRMKDVAQK LAQGEKVEGKYLTYYLAQEKIPMKSIYGNVTELLLAGVDTISSTLSWSLYELAQHPDIQSAVYSEVEEIL QGKQIPSPSDVARMPLLKAVVKEVLRLYPVIPGNARVVADRDIQVGDYIIPKKTLITLCHYATSRDENVF SNPNEFQPDRWLKKEDTHHPYASLPFGFGKRSCIGRRIAELEVYLALARILSHFEVKPEQPGSLVMPMTR TLLVPEKEINLQFLER >CYP3_Rnor NP_671739.2 cytochrome P450 3A9 [Rattus norvegicus] MDLIPNFSMETWLLLVISLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFWEFDKYCHKKYGKLWGLYDGRQP VLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNM RQGSEEGKPTSMKDIFGAYSMDVITATSFGVNVDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSM FPRDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAGYETTSSALSFVLYL LAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFA LHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIPLKLSKQ GLLQPEKPLLLKVVSRDETVNGA >CYP46_Rnor MSPGLLLLGSAVLLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEACGRVLQDVFLDWAKK YGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRAIQTVFGERLFGQGLVSECDYGRWYKQRRV MDLAFSRSSLVSLMGTFNEKAEQLMEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKP LSQAVKVMLEGISASRNTLAKFMPGKRKQLREIRESIRLLRQVGKDWVQRRREALKRGEDVPADILTQIL KAEEGAQDDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRL QYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA PKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRG WQPAPPPPPC