# Electronic Supplementary Material (ESI) for Chemical Science. # This journal is © The Royal Society of Chemistry 2019 ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_2-27_THF_oX_100K_2-fold_publ _database_code_depnum_ccdc_archive 'CCDC 1915299' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2019-05-07 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C14 H20 O8, 8.75(O)' _chemical_formula_sum 'C14 H20 O16.75' _chemical_formula_weight 456.30 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system cubic _space_group_IT_number 201 _space_group_name_H-M_alt 'P n -3' _space_group_name_Hall '-P 2ab 2bc 3' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+1/2, -y+1/2, z' '-x+1/2, y, -z+1/2' 'x, -y+1/2, -z+1/2' 'z, x, y' 'z, -x+1/2, -y+1/2' '-z+1/2, -x+1/2, y' '-z+1/2, x, -y+1/2' 'y, z, x' '-y+1/2, z, -x+1/2' 'y, -z+1/2, -x+1/2' '-y+1/2, -z+1/2, x' '-x, -y, -z' 'x-1/2, y-1/2, -z' 'x-1/2, -y, z-1/2' '-x, y-1/2, z-1/2' '-z, -x, -y' '-z, x-1/2, y-1/2' 'z-1/2, x-1/2, -y' 'z-1/2, -x, y-1/2' '-y, -z, -x' 'y-1/2, -z, x-1/2' '-y, z-1/2, x-1/2' 'y-1/2, z-1/2, -x' _cell_length_a 11.4074(5) _cell_length_b 11.4074(5) _cell_length_c 11.4074(5) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 1484.4(2) _cell_formula_units_Z 2 _cell_measurement_reflns_used 6150 _cell_measurement_temperature 200 _cell_measurement_theta_max 29.768 _cell_measurement_theta_min 2.525 _shelx_estimated_absorpt_T_max 0.964 _shelx_estimated_absorpt_T_min 0.963 _exptl_absorpt_coefficient_mu 0.097 _exptl_absorpt_correction_T_max 0.7461 _exptl_absorpt_correction_T_min 0.4751 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ? _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.021 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description prism _exptl_crystal_F_000 476 _exptl_crystal_size_max 0.397 _exptl_crystal_size_mid 0.385 _exptl_crystal_size_min 0.379 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0579 _diffrn_reflns_av_unetI/netI 0.0236 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 1.000 _diffrn_reflns_limit_h_max 16 _diffrn_reflns_limit_h_min -12 _diffrn_reflns_limit_k_max 16 _diffrn_reflns_limit_k_min -16 _diffrn_reflns_limit_l_max 14 _diffrn_reflns_limit_l_min -16 _diffrn_reflns_number 15739 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 1.000 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 30.472 _diffrn_reflns_theta_min 1.785 _diffrn_ambient_temperature 200 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 656 _reflns_number_total 761 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'ShelXT (Sheldrick, 2015)' _refine_diff_density_max 0.338 _refine_diff_density_min -0.420 _refine_diff_density_rms 0.110 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.196 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 76 _refine_ls_number_reflns 761 _refine_ls_number_restraints 36 _refine_ls_R_factor_all 0.0928 _refine_ls_R_factor_gt 0.0859 _refine_ls_restrained_S_all 1.271 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1422P)^2^+0.1067P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.2151 _refine_ls_wR_factor_ref 0.2255 _refine_special_details ; Refined as a 2-component twin. ; _olex2_refinement_description ; 1. Twinned data refinement Scales: 0.506(13) 0.494(13) 2. Fixed Uiso At 1.2 times of: All C(H,H) groups At 1.5 times of: All O(H) groups 3. Restrained distances H1-H2_$1 2.1 with sigma of 0.04 H2-H1_$2 2.1 with sigma of 0.04 4. Restrained planarity H2_$1, O2_$1, C3, O1, H1 with sigma of 0.001 H2, O2, C3, O1_$2, H1_$2 with sigma of 0.001 5. Uiso/Uaniso restraints and constraints Uanis(O5S) \\sim Ueq, Uanis(O4S) \\sim Ueq, Uanis(O2S) \\sim Ueq, Uanis(O3S) \\sim Ueq, Uanis(O1S) \\sim Ueq: with sigma of 0.01 and sigma for terminal atoms of 0.02 6. Others Fixed Sof: O1(0.33333) H1(0.33333) O2(0.33333) H2(0.33333) H1A(0.5) H1B(0.5) O1S(0.125) O2S(0.125) O3S(0.125) O4S(0.25) O5S(0.04167) O6S(0.0625) 7.a Secondary CH2 refined with riding coordinates: C1(H1A,H1B) 7.b Idealised tetrahedral OH refined as rotating group: O1(H1), O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.6142(7) 0.5875(7) 0.4913(4) 0.073(2) Uani 0.3333 1 d . . . A 1 H1 H 0.5647 0.5420 0.4612 0.110 Uiso 0.3333 1 calc DGR . . A 1 O2 O 0.5430(8) 0.6449(5) 0.5151(7) 0.101(4) Uani 0.3333 1 d . . . A 2 H2 H 0.5031 0.5952 0.4781 0.151 Uiso 0.3333 1 calc DGR . . A 2 C1 C 0.7500 0.7500 0.59417(12) 0.0307(5) Uani 1 2 d S T P . . H1A H 0.7997 0.7003 0.5433 0.037 Uiso 0.5 1 calc R . . . . H1B H 0.7003 0.7997 0.5433 0.037 Uiso 0.5 1 calc R . . . . C2 C 0.67231(8) 0.67231(8) 0.67231(8) 0.0289(5) Uani 1 3 d S T P . . C3 C 0.59580(9) 0.59580(9) 0.59580(9) 0.0339(5) Uani 1 3 d S T P . . O1S O 0.357(4) 0.811(4) 0.460(4) 0.142(13) Uani 0.125 1 d . U . B 5 O2S O 0.420(3) 0.854(2) 0.429(3) 0.093(7) Uani 0.125 1 d . U . C 3 O3S O 0.389(3) 0.868(3) 0.4776(19) 0.078(6) Uani 0.125 1 d . U . D 4 O4S O 0.5146(14) 0.9500(11) 0.4279(11) 0.101(4) Uani 0.25 1 d . U . . 2 O5S O 0.5000 1.0000 0.5000 0.092(6) Uani 0.25 6 d S TU P E 1 O6S O 0.7500 0.881(4) 0.2500 0.26(4) Uani 0.125 2 d S T P F 6 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.100(5) 0.087(5) 0.0327(17) -0.021(2) 0.017(3) -0.060(4) O2 0.158(9) 0.049(2) 0.095(5) 0.025(3) -0.100(6) -0.033(4) C1 0.0290(9) 0.0361(11) 0.0269(7) 0.000 0.000 -0.0018(5) C2 0.0289(5) 0.0289(5) 0.0289(5) -0.0022(3) -0.0022(3) -0.0022(3) C3 0.0339(5) 0.0339(5) 0.0339(5) -0.0029(3) -0.0029(3) -0.0029(3) O1S 0.15(2) 0.125(18) 0.15(2) 0.032(15) -0.024(15) 0.066(15) O2S 0.094(13) 0.105(13) 0.080(13) 0.045(12) -0.004(9) 0.017(12) O3S 0.092(13) 0.089(13) 0.055(10) 0.015(9) -0.014(10) 0.026(11) O4S 0.087(7) 0.098(7) 0.119(8) 0.062(6) -0.021(7) 0.003(6) O5S 0.092(6) 0.092(6) 0.092(6) 0.023(5) -0.023(5) 0.023(5) O6S 0.59(13) 0.15(3) 0.047(13) 0.000 -0.06(4) 0.000 _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 H1 0.8400 . ? O1 C3 1.215(5) . ? O2 H2 0.8400 . ? O2 C3 1.235(5) . ? C1 H1A 0.9900 . ? C1 H1B 0.9900 . ? C1 C2 1.5380(10) . ? C1 C2 1.5380(10) 2_665 ? C2 C1 1.5380(10) 5 ? C2 C1 1.5380(10) 9 ? C2 C3 1.512(2) . ? C3 O1 1.215(5) 5 ? C3 O1 1.215(5) 9 ? C3 O2 1.235(5) 5 ? C3 O2 1.235(5) 9 ? O4S O4S 1.019(14) 18_665 ? O4S O4S 1.76(2) 12_665 ? O4S O4S 1.76(2) 6_566 ? O4S O4S 1.019(14) 24_566 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C3 O1 H1 109.5 . . ? C3 O2 H2 109.5 . . ? H1A C1 H1B 108.3 . . ? C2 C1 H1A 109.8 2_665 . ? C2 C1 H1A 109.8 . . ? C2 C1 H1B 109.8 2_665 . ? C2 C1 H1B 109.8 . . ? C2 C1 C2 109.16(13) 2_665 . ? C1 C2 C1 109.63(7) . 9 ? C1 C2 C1 109.63(7) . 5 ? C1 C2 C1 109.63(7) 9 5 ? C3 C2 C1 109.32(7) . 5 ? C3 C2 C1 109.32(7) . . ? C3 C2 C1 109.32(7) . 9 ? O1 C3 O1 96.1(3) 9 . ? O1 C3 O1 96.1(3) . 5 ? O1 C3 O1 96.1(3) 9 5 ? O1 C3 C2 120.8(2) . . ? O1 C3 C2 120.8(2) 5 . ? O1 C3 C2 120.8(2) 9 . ? O2 C3 O2 101.3(3) . 5 ? O2 C3 O2 101.3(3) 5 9 ? O2 C3 O2 101.3(3) . 9 ? O2 C3 C2 116.8(2) . . ? O2 C3 C2 116.8(2) 9 . ? O2 C3 C2 116.8(2) 5 . ? O4S O4S O4S 119.1(5) 18_665 24_566 ? O4S O4S O4S 30.5(2) 24_566 6_566 ? O4S O4S O4S 90.002(5) 18_665 6_566 ? O4S O4S O4S 30.5(2) 18_665 12_665 ? O4S O4S O4S 60.001(4) 12_665 6_566 ? O4S O4S O4S 90.002(2) 24_566 12_665 ? _shelx_res_file ; pc_thf_ox_100k.res created by SHELXL-2014/7 TITL pc_thf_ox_100k_a.res in Pn-3 REM Old TITL PC_THF_oX_100K in P2(1)3 REM SHELXT solution in Pn-3 REM R1 0.388, Rweak 0.024, Alpha 0.082, Orientation as input REM Formula found by SHELXT: C8 O6S CELL 0.71073 11.4074 11.4074 11.4074 90 90 90 ZERR 2 0.0005 0.0005 0.0005 0 0 0 LATT 1 SYMM 0.5-X,0.5-Y,+Z SYMM 0.5-X,+Y,0.5-Z SYMM +X,0.5-Y,0.5-Z SYMM +Z,+X,+Y SYMM +Z,0.5-X,0.5-Y SYMM 0.5-Z,0.5-X,+Y SYMM 0.5-Z,+X,0.5-Y SYMM +Y,+Z,+X SYMM 0.5-Y,+Z,0.5-X SYMM +Y,0.5-Z,0.5-X SYMM 0.5-Y,0.5-Z,+X SFAC C H O UNIT 28 40 33.5 EQIV $1 +Z,+X,+Y EQIV $2 +Y,+Z,+X DANG 2.1 H1 H2_$1 DANG 2.1 H2 H1_$2 FLAT 0.001 H2_$1 O2_$1 C3 O1 H1 FLAT 0.001 H2 O2 C3 O1_$2 H1_$2 ISOR 0.01 0.02 O5S O4S O2S O3S O1S L.S. 20 PLAN 20 SIZE 0.397 0.385 0.379 TEMP -173.15 FREE O1 O1_$1 FREE O1 O1_$2 BOND $H list 4 fmap 2 53 acta TWIN -1 0 0 0 0 1 0 1 0 2 REM REM REM WGHT 0.142200 0.106700 BASF 0.49416 FVAR 1.29704 PART 1 O1 3 0.614197 0.587487 0.491257 10.33333 0.09958 0.08738 = 0.03272 -0.02117 0.01687 -0.05971 AFIX 147 H1 2 0.564723 0.541999 0.461166 10.33333 -1.50000 AFIX 0 PART 0 PART 2 O2 3 0.542987 0.644856 0.515067 10.33333 0.15772 0.04863 = 0.09547 0.02493 -0.09960 -0.03262 AFIX 147 H2 2 0.503086 0.595220 0.478100 10.33333 -1.50000 AFIX 0 PART 0 C1 1 0.750000 0.750000 0.594171 10.50000 0.02904 0.03605 = 0.02686 0.00000 0.00000 -0.00182 AFIX 23 H1A 2 0.799734 0.700266 0.543329 10.50000 -1.20000 H1B 2 0.700266 0.799734 0.543329 10.50000 -1.20000 AFIX 0 C2 1 0.672308 0.672308 0.672308 10.33333 0.02894 0.02894 = 0.02894 -0.00217 -0.00217 -0.00217 C3 1 0.595798 0.595798 0.595798 10.33333 0.03389 0.03389 = 0.03389 -0.00294 -0.00294 -0.00294 PART 5 O1S 3 0.357342 0.811336 0.460193 10.12500 0.15030 0.12455 = 0.15018 0.03222 -0.02377 0.06622 PART 0 PART 3 O2S 3 0.420354 0.854244 0.429138 10.12500 0.09352 0.10462 = 0.07980 0.04518 -0.00371 0.01724 PART 0 PART 4 O3S 3 0.389230 0.868489 0.477571 10.12500 0.09213 0.08883 = 0.05451 0.01519 -0.01446 0.02650 PART 0 PART 2 O4S 3 0.514583 0.950000 0.427851 10.25000 0.08697 0.09767 = 0.11945 0.06172 -0.02103 0.00295 PART 0 PART 1 O5S 3 0.500000 1.000000 0.500000 10.04167 0.09157 0.09157 = 0.09157 0.02349 -0.02349 0.02349 PART 0 PART 6 O6S 3 0.750000 0.880549 0.250000 10.06250 0.58716 0.14944 = 0.04712 0.00000 -0.06026 0.00000 HKLF 4 REM pc_thf_ox_100k_a.res in Pn-3 REM R1 = 0.0859 for 656 Fo > 4sig(Fo) and 0.0928 for all 761 data REM 76 parameters refined using 36 restraints END WGHT 0.1433 0.1239 REM Highest difference peak 0.338, deepest hole -0.420, 1-sigma level 0.110 Q1 1 0.7500 1.0036 0.2500 10.50000 0.05 0.34 Q2 1 0.7994 0.9660 0.2530 11.00000 0.05 0.32 Q3 1 0.8560 0.8583 0.2562 11.00000 0.05 0.22 Q4 1 0.3201 0.7243 0.4197 11.00000 0.05 0.21 Q5 1 0.4634 0.8115 0.3985 11.00000 0.05 0.17 Q6 1 0.4393 0.7973 0.4157 11.00000 0.05 0.17 Q7 1 0.4501 0.8717 0.4518 11.00000 0.05 0.17 Q8 1 0.3551 0.8140 0.5190 11.00000 0.05 0.16 Q9 1 0.4031 0.8194 0.4788 11.00000 0.05 0.15 Q10 1 0.4718 0.8395 0.4909 11.00000 0.05 0.15 Q11 1 0.3724 0.8048 0.4939 11.00000 0.05 0.13 Q12 1 0.3033 0.8973 0.4239 11.00000 0.05 0.13 Q13 1 0.3978 0.8981 0.5031 11.00000 0.05 0.12 Q14 1 0.6320 0.7283 0.4032 11.00000 0.05 0.09 Q15 1 0.6765 0.9049 0.5949 11.00000 0.05 0.08 Q16 1 0.2765 0.8739 0.3420 11.00000 0.05 0.08 Q17 1 0.7293 0.8415 0.3730 11.00000 0.05 0.08 Q18 1 0.3980 0.8060 0.5579 11.00000 0.05 0.08 Q19 1 0.5625 0.8344 0.5548 11.00000 0.05 0.07 Q20 1 0.7098 0.7959 0.1609 11.00000 0.05 0.07 ; _shelx_res_checksum 59100 _olex2_submission_special_instructions 'No special instructions were received' loop_ _twin_individual_id _twin_individual_mass_fraction_refined 1 0.506(13) 2 0.494(13) ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_2-2_THF_4-fold_publ _database_code_depnum_ccdc_archive 'CCDC 1915301' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2018-12-06 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C14 H16 O8, 0.25(C4 H8 O)' _chemical_formula_sum 'C15 H18 O8.25' _chemical_formula_weight 330.29 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system tetragonal _space_group_IT_number 88 _space_group_name_H-M_alt 'I 41/a' _space_group_name_Hall '-I 4ad' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+1/2, -y, z+1/2' '-y+3/4, x+1/4, z+1/4' 'y+3/4, -x+3/4, z+3/4' 'x+1/2, y+1/2, z+1/2' '-x+1, -y+1/2, z+1' '-y+5/4, x+3/4, z+3/4' 'y+5/4, -x+5/4, z+5/4' '-x, -y, -z' 'x-1/2, y, -z-1/2' 'y-3/4, -x-1/4, -z-1/4' '-y-3/4, x-3/4, -z-3/4' '-x+1/2, -y+1/2, -z+1/2' 'x, y+1/2, -z' 'y-1/4, -x+1/4, -z+1/4' '-y-1/4, x-1/4, -z-1/4' _cell_length_a 16.4008(15) _cell_length_b 16.4008(15) _cell_length_c 22.397(2) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 6024.5(13) _cell_formula_units_Z 16 _cell_measurement_reflns_used 9946 _cell_measurement_temperature 100 _cell_measurement_theta_max 29.134 _cell_measurement_theta_min 2.484 _shelx_estimated_absorpt_T_max 0.987 _shelx_estimated_absorpt_T_min 0.985 _exptl_absorpt_coefficient_mu 0.120 _exptl_absorpt_correction_T_max 0.7458 _exptl_absorpt_correction_T_min 0.4879 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. wR2(int) was 0.1044 before and 0.0737 after correction. The Ratio of minimum to maximum transmission is 0.6542. The \l/2 correction factor is 0.00150. ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.457 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 2784 _exptl_crystal_size_max 0.124 _exptl_crystal_size_mid 0.118 _exptl_crystal_size_min 0.106 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0493 _diffrn_reflns_av_unetI/netI 0.0317 _diffrn_reflns_Laue_measured_fraction_full 0.999 _diffrn_reflns_Laue_measured_fraction_max 0.999 _diffrn_reflns_limit_h_max 22 _diffrn_reflns_limit_h_min -22 _diffrn_reflns_limit_k_max 15 _diffrn_reflns_limit_k_min -22 _diffrn_reflns_limit_l_max 28 _diffrn_reflns_limit_l_min -30 _diffrn_reflns_number 40618 _diffrn_reflns_point_group_measured_fraction_full 0.999 _diffrn_reflns_point_group_measured_fraction_max 0.999 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 29.134 _diffrn_reflns_theta_min 2.484 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.999 _diffrn_measured_fraction_theta_max 0.999 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 3187 _reflns_number_total 4055 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.485 _refine_diff_density_min -0.271 _refine_diff_density_rms 0.061 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.053 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 238 _refine_ls_number_reflns 4055 _refine_ls_number_restraints 14 _refine_ls_R_factor_all 0.0686 _refine_ls_R_factor_gt 0.0549 _refine_ls_restrained_S_all 1.058 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0725P)^2^+8.5815P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1517 _refine_ls_wR_factor_ref 0.1635 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H,H) groups 2. Restrained distances O7-H7 = O5-H5 = O2-H2 = O4-H4 0.82 with sigma of 0.01 C16-C16_$3 1.51 with sigma of 0.01 3. Rigid body (RIGU) restrains O9, C15, C16 with sigma for 1-2 distances of 0.002 and sigma for 1-3 distances of 0.002 4. Others Fixed Sof: O9(0.25) C15(0.5) H15A(0.5) H15B(0.5) C16(0.5) H16A(0.5) H16B(0.5) 5.a Secondary CH2 refined with riding coordinates: C8(H8A,H8B), C9(H9A,H9B), C2(H2A,H2B), C4(H4A,H4B), C6(H6A,H6B), C7(H7A,H7B), C15(H15A,H15B), C16(H16A,H16B) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O8 O 0.60206(8) 0.71971(7) 0.50630(5) 0.0256(3) Uani 1 1 d . . . . . O7 O 0.64225(8) 0.78721(7) 0.42456(5) 0.0247(3) Uani 1 1 d D . . . . O3 O 0.77747(7) 0.58178(8) 0.24742(5) 0.0268(3) Uani 1 1 d . . . . . O5 O 0.59538(9) 0.34945(7) 0.42386(6) 0.0307(3) Uani 1 1 d D . . . . O6 O 0.62549(9) 0.41762(7) 0.50713(5) 0.0298(3) Uani 1 1 d . . . . . O4 O 0.84384(7) 0.54642(9) 0.33048(5) 0.0309(3) Uani 1 1 d D . . . . O1 O 0.47472(7) 0.55365(9) 0.24134(5) 0.0318(3) Uani 1 1 d . . . . . O2 O 0.40596(7) 0.59421(9) 0.32177(6) 0.0333(3) Uani 1 1 d D . . . . C8 C 0.61757(8) 0.56819(8) 0.45455(6) 0.0158(3) Uani 1 1 d . . . . . H8A H 0.6646 0.5654 0.4822 0.019 Uiso 1 1 calc R . . . . H8B H 0.5670 0.5708 0.4787 0.019 Uiso 1 1 calc R . . . . C5 C 0.61600(8) 0.49213(8) 0.41473(6) 0.0155(3) Uani 1 1 d . . . . . C3 C 0.54739(8) 0.57276(8) 0.33399(6) 0.0156(3) Uani 1 1 d . . . . . C13 C 0.61254(9) 0.41616(9) 0.45368(7) 0.0184(3) Uani 1 1 d . . . . . C1 C 0.70013(8) 0.56474(9) 0.33761(6) 0.0165(3) Uani 1 1 d . . . . . C9 C 0.54962(8) 0.64934(8) 0.37357(6) 0.0163(3) Uani 1 1 d . . . . . H9A H 0.4990 0.6528 0.3976 0.020 Uiso 1 1 calc R . . . . H9B H 0.5532 0.6987 0.3483 0.020 Uiso 1 1 calc R . . . . C2 C 0.62546(8) 0.56936(9) 0.29624(6) 0.0170(3) Uani 1 1 d . . . . . H2A H 0.6291 0.6186 0.2708 0.020 Uiso 1 1 calc R . . . . H2B H 0.6241 0.5209 0.2699 0.020 Uiso 1 1 calc R . . . . C14 C 0.62288(9) 0.72062(9) 0.45395(7) 0.0174(3) Uani 1 1 d . . . . . C10 C 0.62447(8) 0.64466(8) 0.41536(6) 0.0152(3) Uani 1 1 d . . . . . C4 C 0.54150(9) 0.49564(9) 0.37330(6) 0.0168(3) Uani 1 1 d . . . . . H4A H 0.4909 0.4973 0.3973 0.020 Uiso 1 1 calc R . . . . H4B H 0.5399 0.4464 0.3477 0.020 Uiso 1 1 calc R . . . . C6 C 0.69493(9) 0.48791(9) 0.37693(6) 0.0173(3) Uani 1 1 d . . . . . H6A H 0.7431 0.4849 0.4035 0.021 Uiso 1 1 calc R . . . . H6B H 0.6942 0.4386 0.3515 0.021 Uiso 1 1 calc R . . . . C7 C 0.70301(8) 0.64133(9) 0.37784(6) 0.0169(3) Uani 1 1 d . . . . . H7A H 0.7512 0.6388 0.4044 0.020 Uiso 1 1 calc R . . . . H7B H 0.7075 0.6910 0.3529 0.020 Uiso 1 1 calc R . . . . C12 C 0.77749(9) 0.56451(9) 0.30020(7) 0.0198(3) Uani 1 1 d . . . . . C11 C 0.47299(9) 0.57386(9) 0.29368(7) 0.0185(3) Uani 1 1 d . . . . . O9 O 0.5000 0.7500 0.2291(3) 0.0850(19) Uani 0.5 2 d S TU P . . C15 C 0.5688(5) 0.7532(4) 0.1904(3) 0.0836(18) Uani 0.5 1 d . U . . . H15A H 0.5969 0.6998 0.1904 0.100 Uiso 0.5 1 calc R . . . . H15B H 0.6076 0.7950 0.2047 0.100 Uiso 0.5 1 calc R . . . . C16 C 0.5412(4) 0.7741(6) 0.1270(4) 0.0810(18) Uani 0.5 1 d D U . . . H16A H 0.5797 0.7533 0.0964 0.097 Uiso 0.5 1 calc R . . . . H16B H 0.5330 0.8334 0.1214 0.097 Uiso 0.5 1 calc R . . . . H5 H 0.5935(18) 0.3098(12) 0.4465(11) 0.067(9) Uiso 1 1 d D . . . . H7 H 0.642(2) 0.8242(14) 0.4497(11) 0.083(10) Uiso 1 1 d D . . . . H2 H 0.3695(14) 0.5948(19) 0.2960(10) 0.073(9) Uiso 1 1 d D . . . . H4 H 0.8828(13) 0.545(2) 0.3069(11) 0.078(10) Uiso 1 1 d D . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O8 0.0361(6) 0.0186(5) 0.0220(6) -0.0036(4) 0.0049(5) -0.0015(5) O7 0.0352(6) 0.0158(5) 0.0232(6) -0.0008(4) -0.0017(5) -0.0031(4) O3 0.0198(5) 0.0396(7) 0.0211(6) 0.0033(5) 0.0030(4) 0.0016(5) O5 0.0524(8) 0.0144(5) 0.0252(6) 0.0020(4) -0.0058(5) -0.0031(5) O6 0.0503(8) 0.0185(5) 0.0207(6) 0.0025(4) -0.0034(5) -0.0020(5) O4 0.0165(5) 0.0512(8) 0.0250(6) 0.0068(5) 0.0027(4) 0.0062(5) O1 0.0210(6) 0.0509(8) 0.0234(6) -0.0090(5) -0.0044(4) 0.0072(5) O2 0.0167(6) 0.0567(9) 0.0266(6) -0.0111(6) -0.0034(5) 0.0050(5) C8 0.0173(6) 0.0146(6) 0.0156(7) -0.0005(5) 0.0002(5) 0.0007(5) C5 0.0163(6) 0.0135(6) 0.0167(7) 0.0006(5) -0.0001(5) 0.0003(5) C3 0.0142(6) 0.0158(6) 0.0168(7) -0.0003(5) -0.0016(5) 0.0006(5) C13 0.0183(7) 0.0154(6) 0.0215(7) 0.0010(5) 0.0008(5) 0.0015(5) C1 0.0141(6) 0.0185(6) 0.0169(7) 0.0002(5) 0.0009(5) 0.0015(5) C9 0.0157(6) 0.0150(6) 0.0183(7) -0.0016(5) -0.0016(5) 0.0020(5) C2 0.0153(6) 0.0197(7) 0.0161(7) -0.0001(5) -0.0003(5) 0.0026(5) C14 0.0166(6) 0.0155(6) 0.0201(7) -0.0015(5) -0.0034(5) 0.0009(5) C10 0.0156(6) 0.0135(6) 0.0166(7) -0.0010(5) -0.0010(5) 0.0003(5) C4 0.0170(6) 0.0149(6) 0.0185(7) -0.0010(5) -0.0012(5) -0.0017(5) C6 0.0165(6) 0.0169(6) 0.0186(7) 0.0006(5) 0.0006(5) 0.0037(5) C7 0.0151(6) 0.0171(6) 0.0186(7) 0.0005(5) 0.0001(5) -0.0011(5) C12 0.0164(6) 0.0212(7) 0.0217(7) -0.0010(5) 0.0003(5) 0.0014(5) C11 0.0170(6) 0.0187(7) 0.0198(7) -0.0009(5) -0.0013(5) 0.0007(5) O9 0.111(4) 0.074(4) 0.070(3) 0.000 0.000 -0.046(3) C15 0.104(4) 0.061(4) 0.086(3) 0.019(3) -0.001(3) -0.023(3) C16 0.081(5) 0.079(5) 0.083(3) 0.005(3) 0.007(3) -0.003(4) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O8 C14 1.2213(19) . ? O7 C14 1.3140(18) . ? O7 H7 0.827(10) . ? O3 C12 1.2155(19) . ? O5 C13 1.3123(18) . ? O5 H5 0.825(10) . ? O6 C13 1.2162(19) . ? O4 C12 1.3161(18) . ? O4 H4 0.830(10) . ? O1 C11 1.2184(19) . ? O2 C11 1.3100(18) . ? O2 H2 0.832(10) . ? C8 H8A 0.9900 . ? C8 H8B 0.9900 . ? C8 C5 1.5336(19) . ? C8 C10 1.5351(19) . ? C5 C13 1.5220(19) . ? C5 C4 1.5355(19) . ? C5 C6 1.5483(19) . ? C3 C9 1.5378(19) . ? C3 C2 1.5353(19) . ? C3 C4 1.5440(19) . ? C3 C11 1.5180(19) . ? C1 C2 1.5376(19) . ? C1 C6 1.5397(19) . ? C1 C7 1.547(2) . ? C1 C12 1.520(2) . ? C9 H9A 0.9900 . ? C9 H9B 0.9900 . ? C9 C10 1.5456(19) . ? C2 H2A 0.9900 . ? C2 H2B 0.9900 . ? C14 C10 1.5165(19) . ? C10 C7 1.5389(19) . ? C4 H4A 0.9900 . ? C4 H4B 0.9900 . ? C6 H6A 0.9900 . ? C6 H6B 0.9900 . ? C7 H7A 0.9900 . ? C7 H7B 0.9900 . ? O9 C15 1.424(8) . ? O9 C15 1.424(8) 6_564 ? C15 H15A 0.9900 . ? C15 H15B 0.9900 . ? C15 C16 1.529(11) . ? C16 C16 1.566(8) 6_564 ? C16 H16A 0.9900 . ? C16 H16B 0.9900 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C14 O7 H7 106(2) . . ? C13 O5 H5 111(2) . . ? C12 O4 H4 108(2) . . ? C11 O2 H2 106(2) . . ? H8A C8 H8B 108.2 . . ? C5 C8 H8A 109.8 . . ? C5 C8 H8B 109.8 . . ? C5 C8 C10 109.47(11) . . ? C10 C8 H8A 109.8 . . ? C10 C8 H8B 109.8 . . ? C8 C5 C4 109.53(11) . . ? C8 C5 C6 109.90(11) . . ? C13 C5 C8 109.47(11) . . ? C13 C5 C4 110.32(11) . . ? C13 C5 C6 107.94(11) . . ? C4 C5 C6 109.66(11) . . ? C9 C3 C4 109.99(11) . . ? C2 C3 C9 109.09(11) . . ? C2 C3 C4 109.66(11) . . ? C11 C3 C9 110.63(11) . . ? C11 C3 C2 110.07(11) . . ? C11 C3 C4 107.37(11) . . ? O5 C13 C5 113.51(13) . . ? O6 C13 O5 123.70(14) . . ? O6 C13 C5 122.78(13) . . ? C2 C1 C6 109.93(11) . . ? C2 C1 C7 109.59(11) . . ? C6 C1 C7 109.46(11) . . ? C12 C1 C2 109.43(11) . . ? C12 C1 C6 111.06(11) . . ? C12 C1 C7 107.32(11) . . ? C3 C9 H9A 109.9 . . ? C3 C9 H9B 109.9 . . ? C3 C9 C10 109.12(11) . . ? H9A C9 H9B 108.3 . . ? C10 C9 H9A 109.9 . . ? C10 C9 H9B 109.9 . . ? C3 C2 C1 109.53(11) . . ? C3 C2 H2A 109.8 . . ? C3 C2 H2B 109.8 . . ? C1 C2 H2A 109.8 . . ? C1 C2 H2B 109.8 . . ? H2A C2 H2B 108.2 . . ? O8 C14 O7 123.96(13) . . ? O8 C14 C10 122.82(13) . . ? O7 C14 C10 113.14(13) . . ? C8 C10 C9 109.17(11) . . ? C8 C10 C7 110.18(11) . . ? C14 C10 C8 110.12(11) . . ? C14 C10 C9 106.90(11) . . ? C14 C10 C7 110.78(11) . . ? C7 C10 C9 109.62(11) . . ? C5 C4 C3 109.00(11) . . ? C5 C4 H4A 109.9 . . ? C5 C4 H4B 109.9 . . ? C3 C4 H4A 109.9 . . ? C3 C4 H4B 109.9 . . ? H4A C4 H4B 108.3 . . ? C5 C6 H6A 109.9 . . ? C5 C6 H6B 109.9 . . ? C1 C6 C5 108.82(11) . . ? C1 C6 H6A 109.9 . . ? C1 C6 H6B 109.9 . . ? H6A C6 H6B 108.3 . . ? C1 C7 H7A 109.9 . . ? C1 C7 H7B 109.9 . . ? C10 C7 C1 108.75(11) . . ? C10 C7 H7A 109.9 . . ? C10 C7 H7B 109.9 . . ? H7A C7 H7B 108.3 . . ? O3 C12 O4 123.63(14) . . ? O3 C12 C1 122.35(13) . . ? O4 C12 C1 113.98(13) . . ? O1 C11 O2 123.43(14) . . ? O1 C11 C3 123.39(13) . . ? O2 C11 C3 113.07(13) . . ? C15 O9 C15 104.9(7) 6_564 . ? O9 C15 H15A 109.7 . . ? O9 C15 H15B 109.7 . . ? O9 C15 C16 109.9(6) . . ? H15A C15 H15B 108.2 . . ? C16 C15 H15A 109.7 . . ? C16 C15 H15B 109.7 . . ? C15 C16 C16 98.2(4) . 6_564 ? C15 C16 H16A 112.1 . . ? C15 C16 H16B 112.1 . . ? C16 C16 H16A 112.1 6_564 . ? C16 C16 H16B 112.1 6_564 . ? H16A C16 H16B 109.8 . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O5 H5 O8 0.825(10) 1.822(11) 2.6431(16) 173(3) 14_546 O7 H7 O6 0.827(10) 1.832(12) 2.6440(16) 167(3) 14_556 O2 H2 O3 0.832(10) 1.807(12) 2.6236(16) 167(3) 10_556 O4 H4 O1 0.830(10) 1.860(11) 2.6851(17) 172(3) 10_656 _shelx_res_file ; pc_ht_8_i22_100k.res created by SHELXL-2014/7 TITL pc_ht_8_i22_100k_a.res in I4(1)/a REM Old TITL PC_HT_8_i22_100K in I4(1)/a REM SHELXT solution in I4(1)/a REM R1 0.230, Rweak 0.003, Alpha 0.020, Orientation as input REM Formula found by SHELXT: C22 CELL 0.71073 16.4008 16.4008 22.3972 90 90 90 ZERR 16 0.0015 0.0015 0.0022 0 0 0 LATT 2 SYMM 0.5-X,-Y,0.5+Z SYMM 0.75-Y,0.25+X,0.25+Z SYMM 0.75+Y,0.75-X,0.75+Z SFAC C H O UNIT 240 288 132 EQIV $1 -0.25+Y,1.25-X,0.25-Z EQIV $2 1.25-Y,0.25+X,0.25-Z EQIV $3 1-X,1.5-Y,+Z EQIV $4 +X,0.5+Y,1-Z EQIV $5 +X,-0.5+Y,1-Z EQIV $6 0.5+X,+Y,0.5-Z EQIV $7 -0.5+X,+Y,0.5-Z DFIX 0.82 0.01 O7 H7 O5 H5 O2 H2 O4 H4 DFIX 1.51 0.01 C16 C16_$3 RIGU 0.002 0.002 O9 C15 C16 L.S. 15 PLAN 20 SIZE 0.106 0.118 0.124 TEMP -173.15 HTAB O7 O6_$4 HTAB O5 O8_$5 HTAB O4 O1_$6 HTAB O2 O3_$7 FREE C15 C16_$1 FREE C15 H16b_$1 FREE C16 C16_$1 FREE C16 C16_$2 FREE C16 H16a_$2 FREE C16 H16b_$1 FREE C16 C15_$2 BOND $H list 4 fmap 2 53 ACTA REM REM REM WGHT 0.072500 8.581500 FVAR 0.20385 O8 3 0.602064 0.719714 0.506303 11.00000 0.03614 0.01861 = 0.02202 -0.00362 0.00492 -0.00154 O7 3 0.642246 0.787206 0.424564 11.00000 0.03521 0.01580 = 0.02315 -0.00079 -0.00174 -0.00309 O3 3 0.777475 0.581784 0.247424 11.00000 0.01984 0.03957 = 0.02110 0.00330 0.00300 0.00157 O5 3 0.595381 0.349447 0.423859 11.00000 0.05242 0.01438 = 0.02524 0.00201 -0.00584 -0.00313 O6 3 0.625490 0.417616 0.507131 11.00000 0.05030 0.01847 = 0.02067 0.00253 -0.00335 -0.00202 O4 3 0.843836 0.546418 0.330482 11.00000 0.01650 0.05121 = 0.02499 0.00680 0.00271 0.00624 O1 3 0.474721 0.553647 0.241342 11.00000 0.02103 0.05086 = 0.02337 -0.00896 -0.00437 0.00717 O2 3 0.405956 0.594209 0.321769 11.00000 0.01674 0.05672 = 0.02658 -0.01114 -0.00340 0.00504 C8 1 0.617568 0.568189 0.454552 11.00000 0.01727 0.01459 = 0.01562 -0.00051 0.00025 0.00066 AFIX 23 H8A 2 0.664594 0.565355 0.482186 11.00000 -1.20000 H8B 2 0.567049 0.570797 0.478669 11.00000 -1.20000 AFIX 0 C5 1 0.616001 0.492133 0.414735 11.00000 0.01630 0.01349 = 0.01669 0.00056 -0.00014 0.00029 C3 1 0.547387 0.572756 0.333990 11.00000 0.01424 0.01575 = 0.01684 -0.00026 -0.00159 0.00061 C13 1 0.612537 0.416155 0.453675 11.00000 0.01832 0.01544 = 0.02152 0.00096 0.00084 0.00154 C1 1 0.700131 0.564743 0.337610 11.00000 0.01406 0.01853 = 0.01693 0.00016 0.00086 0.00148 C9 1 0.549625 0.649342 0.373565 11.00000 0.01565 0.01504 = 0.01827 -0.00163 -0.00163 0.00201 AFIX 23 H9A 2 0.499043 0.652805 0.397554 11.00000 -1.20000 H9B 2 0.553232 0.698714 0.348272 11.00000 -1.20000 AFIX 0 C2 1 0.625457 0.569364 0.296242 11.00000 0.01526 0.01972 = 0.01607 -0.00014 -0.00030 0.00259 AFIX 23 H2A 2 0.629146 0.618599 0.270813 11.00000 -1.20000 H2B 2 0.624063 0.520929 0.269883 11.00000 -1.20000 AFIX 0 C14 1 0.622879 0.720624 0.453951 11.00000 0.01664 0.01551 = 0.02013 -0.00155 -0.00344 0.00086 C10 1 0.624469 0.644664 0.415359 11.00000 0.01560 0.01353 = 0.01655 -0.00098 -0.00103 0.00026 C4 1 0.541498 0.495643 0.373296 11.00000 0.01696 0.01485 = 0.01847 -0.00100 -0.00118 -0.00170 AFIX 23 H4A 2 0.490856 0.497286 0.397321 11.00000 -1.20000 H4B 2 0.539884 0.446414 0.347744 11.00000 -1.20000 AFIX 0 C6 1 0.694927 0.487912 0.376931 11.00000 0.01646 0.01689 = 0.01863 0.00060 0.00065 0.00367 AFIX 23 H6A 2 0.743087 0.484860 0.403485 11.00000 -1.20000 H6B 2 0.694170 0.438552 0.351494 11.00000 -1.20000 AFIX 0 C7 1 0.703009 0.641334 0.377842 11.00000 0.01512 0.01713 = 0.01858 0.00048 0.00009 -0.00105 AFIX 23 H7A 2 0.751175 0.638833 0.404422 11.00000 -1.20000 H7B 2 0.707476 0.690957 0.352887 11.00000 -1.20000 AFIX 0 C12 1 0.777489 0.564511 0.300201 11.00000 0.01635 0.02120 = 0.02170 -0.00098 0.00031 0.00144 C11 1 0.472995 0.573855 0.293676 11.00000 0.01697 0.01870 = 0.01983 -0.00087 -0.00132 0.00065 O9 3 0.500000 0.750000 0.229108 10.25000 0.11140 0.07364 = 0.06995 0.00000 0.00000 -0.04567 C15 1 0.568756 0.753176 0.190357 10.50000 0.10366 0.06148 = 0.08568 0.01904 -0.00108 -0.02333 AFIX 23 H15A 2 0.596938 0.699796 0.190400 10.50000 -1.20000 H15B 2 0.607602 0.795001 0.204730 10.50000 -1.20000 AFIX 0 C16 1 0.541244 0.774054 0.126959 10.50000 0.08055 0.07947 = 0.08307 0.00542 0.00678 -0.00348 AFIX 23 H16A 2 0.579661 0.753325 0.096430 10.50000 -1.20000 H16B 2 0.532978 0.833369 0.121427 10.50000 -1.20000 AFIX 0 H5 2 0.593536 0.309766 0.446455 11.00000 0.06684 H7 2 0.642080 0.824212 0.449659 11.00000 0.08294 H2 2 0.369474 0.594819 0.295962 11.00000 0.07347 H4 2 0.882834 0.544707 0.306893 11.00000 0.07847 HKLF 4 REM pc_ht_8_i22_100k_a.res in I4(1)/a REM R1 = 0.0549 for 3187 Fo > 4sig(Fo) and 0.0686 for all 4055 data REM 238 parameters refined using 14 restraints END WGHT 0.0725 8.5808 REM Highest difference peak 0.485, deepest hole -0.271, 1-sigma level 0.061 Q1 1 0.6144 0.4568 0.4318 11.00000 0.05 0.48 Q2 1 0.6237 0.6807 0.4366 11.00000 0.05 0.46 Q3 1 0.7339 0.5638 0.3181 11.00000 0.05 0.44 Q4 1 0.5092 0.5738 0.3142 11.00000 0.05 0.41 Q5 1 0.6612 0.5642 0.3193 11.00000 0.05 0.40 Q6 1 0.6242 0.6055 0.4306 11.00000 0.05 0.40 Q7 1 0.6531 0.4889 0.3936 11.00000 0.05 0.38 Q8 1 0.5751 0.4922 0.3989 11.00000 0.05 0.38 Q9 1 0.6148 0.5272 0.4366 11.00000 0.05 0.38 Q10 1 0.5520 0.8053 0.1012 11.00000 0.05 0.38 Q11 1 0.5487 0.6124 0.3559 11.00000 0.05 0.37 Q12 1 0.5469 0.5317 0.3522 11.00000 0.05 0.36 Q13 1 0.6957 0.5255 0.3563 11.00000 0.05 0.35 Q14 1 0.5590 0.3678 0.4484 11.00000 0.05 0.34 Q15 1 0.5640 0.7294 0.4865 11.00000 0.05 0.34 Q16 1 0.5851 0.5705 0.3104 11.00000 0.05 0.34 Q17 1 0.6878 0.7684 0.4496 11.00000 0.05 0.34 Q18 1 0.4658 0.6591 0.2659 11.00000 0.05 0.34 Q19 1 0.6625 0.6433 0.3958 11.00000 0.05 0.33 Q20 1 0.7000 0.6024 0.3578 11.00000 0.05 0.33 ; _shelx_res_checksum 10859 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_2-34_THF-1-2-dimethoxybenzene_publ _database_code_depnum_ccdc_archive 'CCDC 1915303' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2018-12-05 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety '2(C14 H16 O8), 4(C8 H10 O2)' _chemical_formula_sum 'C60 H72 O24' _chemical_formula_weight 1177.17 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system tetragonal _space_group_IT_number 88 _space_group_name_H-M_alt 'I 41/a' _space_group_name_Hall '-I 4ad' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+1/2, -y, z+1/2' '-y+3/4, x+1/4, z+1/4' 'y+3/4, -x+3/4, z+3/4' 'x+1/2, y+1/2, z+1/2' '-x+1, -y+1/2, z+1' '-y+5/4, x+3/4, z+3/4' 'y+5/4, -x+5/4, z+5/4' '-x, -y, -z' 'x-1/2, y, -z-1/2' 'y-3/4, -x-1/4, -z-1/4' '-y-3/4, x-3/4, -z-3/4' '-x+1/2, -y+1/2, -z+1/2' 'x, y+1/2, -z' 'y-1/4, -x+1/4, -z+1/4' '-y-1/4, x-1/4, -z-1/4' _cell_length_a 16.2380(2) _cell_length_b 16.2380(2) _cell_length_c 22.3825(3) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 5901.65(17) _cell_formula_units_Z 4 _cell_measurement_temperature 100.01(10) _cell_measurement_reflns_used 8969 _cell_measurement_theta_min 2.4890 _cell_measurement_theta_max 30.0790 _shelx_estimated_absorpt_T_max 0.993 _shelx_estimated_absorpt_T_min 0.989 _exptl_absorpt_coefficient_mu 0.103 _exptl_absorpt_correction_T_min 0.71430 _exptl_absorpt_correction_T_max 1.00000 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; CrysAlisPro 1.171.39.46e (Rigaku Oxford Diffraction, 2018) Empirical absorption correction using spherical harmonics, implemented in SCALE3 ABSPACK scaling algorithm. ; _oxdiff_exptl_absorpt_empirical_full_min 0.643 _oxdiff_exptl_absorpt_empirical_full_max 1.395 _oxdiff_exptl_absorpt_empirical_details ; Empirical correction (ABSPACK) includes: - Absorption correction using spherical harmonics - Frame scaling ; _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.325 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 2496 _exptl_crystal_size_max 0.11 _exptl_crystal_size_mid 0.09 _exptl_crystal_size_min 0.07 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0789 _diffrn_reflns_av_unetI/netI 0.0286 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 1.000 _diffrn_reflns_limit_h_max 20 _diffrn_reflns_limit_h_min -20 _diffrn_reflns_limit_k_max 16 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 27 _diffrn_reflns_limit_l_min -27 _diffrn_reflns_number 45910 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 1.000 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.360 _diffrn_reflns_theta_min 2.509 _diffrn_ambient_temperature 100.0 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_orient_matrix_type 'CrysAlisPro convention (1999,Acta A55,543-557)' _diffrn_orient_matrix_UB_11 -0.0227345000 _diffrn_orient_matrix_UB_12 -0.0050706000 _diffrn_orient_matrix_UB_13 -0.0267912000 _diffrn_orient_matrix_UB_21 -0.0353263000 _diffrn_orient_matrix_UB_22 -0.0107974000 _diffrn_orient_matrix_UB_23 0.0168476000 _diffrn_orient_matrix_UB_31 -0.0119427000 _diffrn_orient_matrix_UB_32 0.0419919000 _diffrn_orient_matrix_UB_33 0.0011003000 _diffrn_measurement_details ; List of Runs (angles in degrees, time in seconds): # Type Start End Width t~exp~ \w \q \k \f Frames #-------------------------------------------------------------------------- 1 \w -109.00 16.00 1.00 10.00 -- -20.00 -68.00 0.00 125 2 \w -109.00 16.00 1.00 10.00 -- -20.00 -68.00 120.00 125 3 \w -109.00 16.00 1.00 10.00 -- -20.00 -68.00 240.00 125 4 \w -109.00 16.00 1.00 10.00 -- -20.00 -30.00 90.00 125 5 \w -90.00 90.00 1.00 1.00 -- 0.00 0.00 0.00 180 ; _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type Rigaku_AFC12K_724P_007HF_Mo _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 2383 _reflns_number_total 3006 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement ; 'CrysAlisPro 1.171.39.46e (Rigaku OD, 2018)' ; _computing_data_collection ; 'CrysAlisPro 1.171.39.46e (Rigaku OD, 2018)' ; _computing_data_reduction ; 'CrysAlisPro 1.171.39.46e (Rigaku OD, 2018)' ; _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'ShelXL (Sheldrick, 2015)' _computing_structure_solution ? _refine_diff_density_max 0.330 _refine_diff_density_min -0.250 _refine_diff_density_rms 0.049 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.064 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 195 _refine_ls_number_reflns 3006 _refine_ls_number_restraints 0 _refine_ls_R_factor_all 0.0639 _refine_ls_R_factor_gt 0.0511 _refine_ls_restrained_S_all 1.064 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0692P)^2^+4.1353P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1334 _refine_ls_wR_factor_ref 0.1421 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups, All C(H,H) groups At 1.5 times of: All C(H,H,H) groups, All O(H) groups 2. Others Fixed Sof: H9A(0.5) H9B(0.5) H14A(0.5) H14B(0.5) 3.a Secondary CH2 refined with riding coordinates: C9(H9A,H9B), C14(H14A,H14B), C11(H11A,H11B), C16(H16A,H16B) 3.b Aromatic/amide H refined with riding coordinates: C6(H6), C5(H5), C3(H3), C4(H4) 3.c Idealised Me refined as rotating group: C8(H8A,H8B,H8C), C7(H7A,H7B,H7C) 3.d Idealised tetrahedral OH refined as rotating group: O4(H4A), O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O3 O 0.29084(7) 0.80209(7) 0.19561(5) 0.0294(3) Uani 1 1 d . . . . . O4 O 0.34305(8) 0.69253(8) 0.24158(6) 0.0346(3) Uani 1 1 d . . . . . H4A H 0.2987 0.6954 0.2608 0.052 Uiso 1 1 calc GR . . . . O1 O 0.45331(8) 0.58832(8) 0.50700(6) 0.0345(3) Uani 1 1 d . . . . . O2 O 0.55998(8) 0.54210(7) 0.55886(6) 0.0351(3) Uani 1 1 d . . . . . H2 H 0.5526 0.5005 0.5372 0.053 Uiso 1 1 calc GR . . . . O5 O 0.35617(10) 0.78393(10) 0.40124(7) 0.0516(4) Uani 1 1 d . . . . . O6 O 0.30306(10) 0.92945(10) 0.42300(9) 0.0617(5) Uani 1 1 d . . . . . C13 C 0.34585(9) 0.75214(10) 0.20227(6) 0.0194(3) Uani 1 1 d . . . . . C9 C 0.5000 0.7500 0.54559(9) 0.0185(5) Uani 1 2 d S T P . . H9A H 0.4507 0.7468 0.5197 0.022 Uiso 0.5 1 calc R . . . . H9B H 0.5493 0.7532 0.5197 0.022 Uiso 0.5 1 calc R . . . . C14 C 0.5000 0.7500 0.20463(9) 0.0183(4) Uani 1 2 d S T P . . H14A H 0.5012 0.7994 0.2305 0.022 Uiso 0.5 1 calc R . . . . H14B H 0.4988 0.7006 0.2305 0.022 Uiso 0.5 1 calc R . . . . C15 C 0.42280(9) 0.75183(9) 0.16441(6) 0.0176(3) Uani 1 1 d . . . . . C11 C 0.42707(9) 0.66840(9) 0.62481(6) 0.0180(3) Uani 1 1 d . . . . . H11A H 0.3775 0.6655 0.5992 0.022 Uiso 1 1 calc R . . . . H11B H 0.4288 0.6183 0.6500 0.022 Uiso 1 1 calc R . . . . C12 C 0.50521(9) 0.59658(9) 0.54674(6) 0.0194(3) Uani 1 1 d . . . . . C10 C 0.50500(9) 0.67292(9) 0.58553(6) 0.0180(3) Uani 1 1 d . . . . . C16 C 0.42372(9) 0.82878(9) 0.12489(6) 0.0181(3) Uani 1 1 d . . . . . H16A H 0.4236 0.8789 0.1501 0.022 Uiso 1 1 calc R . . . . H16B H 0.3740 0.8298 0.0993 0.022 Uiso 1 1 calc R . . . . C1 C 0.30447(13) 0.79022(13) 0.44919(9) 0.0406(5) Uani 1 1 d . . . . . C6 C 0.27880(13) 0.72547(13) 0.48469(9) 0.0422(5) Uani 1 1 d . . . . . H6 H 0.2969 0.6711 0.4761 0.051 Uiso 1 1 calc R . . . . C2 C 0.27657(13) 0.87009(13) 0.46177(11) 0.0453(5) Uani 1 1 d . . . . . C5 C 0.22670(13) 0.73933(15) 0.53280(10) 0.0481(6) Uani 1 1 d . . . . . H5 H 0.2089 0.6944 0.5567 0.058 Uiso 1 1 calc R . . . . C3 C 0.22591(13) 0.88302(14) 0.51021(11) 0.0500(6) Uani 1 1 d . . . . . H3 H 0.2080 0.9373 0.5193 0.060 Uiso 1 1 calc R . . . . C4 C 0.20066(13) 0.81773(16) 0.54602(11) 0.0515(6) Uani 1 1 d . . . . . H4 H 0.1657 0.8273 0.5793 0.062 Uiso 1 1 calc R . . . . C8 C 0.38648(16) 0.70448(15) 0.38680(10) 0.0538(6) Uani 1 1 d . . . . . H8A H 0.4218 0.7081 0.3514 0.081 Uiso 1 1 calc GR . . . . H8B H 0.3401 0.6675 0.3786 0.081 Uiso 1 1 calc GR . . . . H8C H 0.4185 0.6830 0.4205 0.081 Uiso 1 1 calc GR . . . . C7 C 0.26800(16) 1.00885(15) 0.42766(18) 0.0743(9) Uani 1 1 d . . . . . H7A H 0.2916 1.0448 0.3969 0.111 Uiso 1 1 calc GR . . . . H7B H 0.2798 1.0317 0.4673 0.111 Uiso 1 1 calc GR . . . . H7C H 0.2083 1.0052 0.4220 0.111 Uiso 1 1 calc GR . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O3 0.0265(6) 0.0314(7) 0.0304(6) 0.0094(5) 0.0083(5) 0.0068(5) O4 0.0291(7) 0.0422(8) 0.0326(7) 0.0186(6) 0.0144(5) 0.0116(6) O1 0.0419(7) 0.0298(7) 0.0318(7) -0.0115(5) -0.0161(6) 0.0083(6) O2 0.0409(8) 0.0280(7) 0.0363(7) -0.0137(5) -0.0144(6) 0.0116(6) O5 0.0561(10) 0.0487(9) 0.0498(9) 0.0045(7) -0.0047(7) 0.0048(8) O6 0.0502(10) 0.0371(9) 0.0977(14) 0.0093(9) 0.0012(9) -0.0013(7) C13 0.0204(8) 0.0222(8) 0.0155(7) -0.0012(6) -0.0002(6) -0.0010(6) C9 0.0204(11) 0.0210(11) 0.0140(10) 0.000 0.000 0.0007(9) C14 0.0213(11) 0.0210(11) 0.0127(9) 0.000 0.000 0.0018(9) C15 0.0186(8) 0.0206(8) 0.0135(7) -0.0002(6) 0.0009(6) 0.0006(6) C11 0.0189(7) 0.0190(7) 0.0160(7) -0.0002(6) 0.0004(6) -0.0012(6) C12 0.0220(8) 0.0204(8) 0.0156(7) 0.0008(6) 0.0025(6) 0.0004(6) C10 0.0197(7) 0.0204(8) 0.0138(7) -0.0001(6) -0.0002(6) -0.0007(6) C16 0.0188(7) 0.0200(8) 0.0155(7) 0.0004(6) 0.0001(6) 0.0007(6) C1 0.0359(11) 0.0429(11) 0.0431(11) -0.0005(9) -0.0152(9) -0.0010(9) C6 0.0410(11) 0.0406(11) 0.0451(11) 0.0000(9) -0.0162(9) 0.0014(9) C2 0.0318(11) 0.0406(12) 0.0633(14) -0.0007(10) -0.0143(10) -0.0031(9) C5 0.0377(11) 0.0568(14) 0.0499(13) 0.0081(11) -0.0147(10) -0.0033(10) C3 0.0357(11) 0.0450(12) 0.0693(15) -0.0121(11) -0.0167(11) 0.0005(10) C4 0.0302(11) 0.0716(16) 0.0526(13) -0.0070(12) -0.0113(10) 0.0021(11) C8 0.0671(15) 0.0565(14) 0.0377(11) -0.0040(10) -0.0119(11) 0.0133(12) C7 0.0449(14) 0.0378(13) 0.140(3) 0.0081(15) 0.0001(16) -0.0022(11) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O3 C13 1.2159(19) . ? O4 H4A 0.8400 . ? O4 C13 1.3088(19) . ? O1 C12 1.2325(19) . ? O2 H2 0.8400 . ? O2 C12 1.2834(19) . ? O5 C1 1.366(3) . ? O5 C8 1.418(3) . ? O6 C2 1.366(3) . ? O6 C7 1.413(3) . ? C13 C15 1.510(2) . ? C9 H9A 0.9900 . ? C9 H9B 0.9900 . ? C9 C10 1.5402(18) 6_564 ? C9 C10 1.5402(18) . ? C14 H14A 0.9900 . ? C14 H14B 0.9900 . ? C14 C15 1.5435(18) . ? C14 C15 1.5435(18) 6_564 ? C15 C16 1.544(2) 12_766 ? C15 C16 1.531(2) . ? C11 H11A 0.9900 . ? C11 H11B 0.9900 . ? C11 C10 1.530(2) 15_566 ? C11 C10 1.543(2) . ? C12 C10 1.514(2) . ? C10 C11 1.530(2) 12_767 ? C16 C15 1.544(2) 15_565 ? C16 H16A 0.9900 . ? C16 H16B 0.9900 . ? C1 C6 1.382(3) . ? C1 C2 1.402(3) . ? C6 H6 0.9500 . ? C6 C5 1.388(3) . ? C2 C3 1.377(3) . ? C5 H5 0.9500 . ? C5 C4 1.374(3) . ? C3 H3 0.9500 . ? C3 C4 1.391(3) . ? C4 H4 0.9500 . ? C8 H8A 0.9800 . ? C8 H8B 0.9800 . ? C8 H8C 0.9800 . ? C7 H7A 0.9800 . ? C7 H7B 0.9800 . ? C7 H7C 0.9800 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C13 O4 H4A 109.5 . . ? C12 O2 H2 109.5 . . ? C1 O5 C8 117.40(18) . . ? C2 O6 C7 118.0(2) . . ? O3 C13 O4 123.39(14) . . ? O3 C13 C15 122.78(14) . . ? O4 C13 C15 113.80(13) . . ? H9A C9 H9B 108.3 . . ? C10 C9 H9A 109.9 . . ? C10 C9 H9A 109.9 6_564 . ? C10 C9 H9B 109.9 6_564 . ? C10 C9 H9B 109.9 . . ? C10 C9 C10 109.04(16) . 6_564 ? H14A C14 H14B 108.3 . . ? C15 C14 H14A 110.0 6_564 . ? C15 C14 H14A 110.0 . . ? C15 C14 H14B 110.0 . . ? C15 C14 H14B 110.0 6_564 . ? C15 C14 C15 108.66(16) 6_564 . ? C13 C15 C14 110.18(12) . . ? C13 C15 C16 107.99(12) . 12_766 ? C13 C15 C16 109.25(12) . . ? C14 C15 C16 109.27(11) . 12_766 ? C16 C15 C14 110.16(11) . . ? C16 C15 C16 109.96(10) . 12_766 ? H11A C11 H11B 108.3 . . ? C10 C11 H11A 109.8 15_566 . ? C10 C11 H11A 109.8 . . ? C10 C11 H11B 109.8 . . ? C10 C11 H11B 109.8 15_566 . ? C10 C11 C10 109.16(14) 15_566 . ? O1 C12 O2 123.46(14) . . ? O1 C12 C10 120.09(13) . . ? O2 C12 C10 116.42(13) . . ? C9 C10 C11 109.04(11) . . ? C11 C10 C9 110.11(11) 12_767 . ? C11 C10 C11 109.78(10) 12_767 . ? C12 C10 C9 109.44(12) . . ? C12 C10 C11 111.54(12) . 12_767 ? C12 C10 C11 106.85(12) . . ? C15 C16 C15 108.89(14) . 15_565 ? C15 C16 H16A 109.9 15_565 . ? C15 C16 H16A 109.9 . . ? C15 C16 H16B 109.9 15_565 . ? C15 C16 H16B 109.9 . . ? H16A C16 H16B 108.3 . . ? O5 C1 C6 125.4(2) . . ? O5 C1 C2 115.17(19) . . ? C6 C1 C2 119.4(2) . . ? C1 C6 H6 119.8 . . ? C1 C6 C5 120.4(2) . . ? C5 C6 H6 119.8 . . ? O6 C2 C1 115.0(2) . . ? O6 C2 C3 125.5(2) . . ? C3 C2 C1 119.5(2) . . ? C6 C5 H5 119.8 . . ? C4 C5 C6 120.3(2) . . ? C4 C5 H5 119.8 . . ? C2 C3 H3 119.5 . . ? C2 C3 C4 120.9(2) . . ? C4 C3 H3 119.5 . . ? C5 C4 C3 119.4(2) . . ? C5 C4 H4 120.3 . . ? C3 C4 H4 120.3 . . ? O5 C8 H8A 109.5 . . ? O5 C8 H8B 109.5 . . ? O5 C8 H8C 109.5 . . ? H8A C8 H8B 109.5 . . ? H8A C8 H8C 109.5 . . ? H8B C8 H8C 109.5 . . ? O6 C7 H7A 109.5 . . ? O6 C7 H7B 109.5 . . ? O6 C7 H7C 109.5 . . ? H7A C7 H7B 109.5 . . ? H7A C7 H7C 109.5 . . ? H7B C7 H7C 109.5 . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O4 H4A O3 0.84 1.75 2.5905(16) 176.5 13_565 O2 H2 O1 0.84 1.75 2.5893(16) 174.8 9_666 _shelx_res_file ; pc_ht_8_i234_100k.res created by SHELXL-2014/7 TITL exp_18_a.res in I4(1)/a REM Old TITL exp_18 in I4(1)/a REM SHELXT solution in I4(1)/a REM R1 0.201, Rweak 0.057, Alpha 0.028, Orientation as input REM Formula found by SHELXT: C16 N O4 CELL 0.71073 16.238 16.238 22.3825 90 90 90 ZERR 4 0.0002 0.0002 0.0003 0 0 0 LATT 2 SYMM 0.5-X,-Y,0.5+Z SYMM 0.75-Y,0.25+X,0.25+Z SYMM 0.75+Y,0.75-X,0.75+Z SFAC C H O UNIT 240 288 96 EQIV $1 0.5-X,1.5-Y,0.5-Z EQIV $2 1-X,1-Y,1-Z L.S. 99 PLAN 20 SIZE 0.11 0.09 0.07 TEMP -173.15 HTAB O4 O3_$1 HTAB O2 O1_$2 BOND $H list 4 fmap 2 53 acta SHEL 999 0.8 OMIT 0 1 1 REM REM REM WGHT 0.069200 4.135300 FVAR 0.18721 O3 3 0.290837 0.802095 0.195610 11.00000 0.02647 0.03141 = 0.03044 0.00935 0.00831 0.00684 O4 3 0.343046 0.692526 0.241576 11.00000 0.02907 0.04224 = 0.03262 0.01858 0.01440 0.01160 AFIX 147 H4A 2 0.298696 0.695361 0.260785 11.00000 -1.50000 AFIX 0 O1 3 0.453308 0.588324 0.507004 11.00000 0.04186 0.02982 = 0.03179 -0.01150 -0.01608 0.00830 O2 3 0.559978 0.542095 0.558858 11.00000 0.04091 0.02797 = 0.03628 -0.01372 -0.01437 0.01158 AFIX 147 H2 2 0.552605 0.500506 0.537190 11.00000 -1.50000 AFIX 0 O5 3 0.356172 0.783926 0.401237 11.00000 0.05614 0.04871 = 0.04983 0.00449 -0.00469 0.00478 O6 3 0.303060 0.929446 0.422995 11.00000 0.05022 0.03712 = 0.09770 0.00929 0.00122 -0.00128 C13 1 0.345849 0.752136 0.202273 11.00000 0.02040 0.02225 = 0.01555 -0.00122 -0.00019 -0.00104 C9 1 0.500000 0.750000 0.545590 10.50000 0.02037 0.02099 = 0.01402 0.00000 0.00000 0.00072 AFIX 23 H9A 2 0.450688 0.746805 0.519683 10.50000 -1.20000 H9B 2 0.549312 0.753196 0.519683 10.50000 -1.20000 AFIX 0 C14 1 0.500000 0.750000 0.204629 10.50000 0.02128 0.02097 = 0.01273 0.00000 0.00000 0.00182 AFIX 23 H14A 2 0.501168 0.799418 0.230520 10.50000 -1.20000 H14B 2 0.498830 0.700583 0.230521 10.50000 -1.20000 AFIX 0 C15 1 0.422800 0.751826 0.164415 11.00000 0.01863 0.02062 = 0.01350 -0.00018 0.00087 0.00064 C11 1 0.427067 0.668400 0.624813 11.00000 0.01889 0.01898 = 0.01604 -0.00016 0.00038 -0.00119 AFIX 23 H11A 2 0.377458 0.665463 0.599190 11.00000 -1.20000 H11B 2 0.428840 0.618291 0.649975 11.00000 -1.20000 AFIX 0 C12 1 0.505207 0.596576 0.546736 11.00000 0.02205 0.02044 = 0.01562 0.00083 0.00248 0.00038 C10 1 0.504995 0.672922 0.585526 11.00000 0.01975 0.02037 = 0.01379 -0.00014 -0.00023 -0.00067 C16 1 0.423719 0.828781 0.124887 11.00000 0.01884 0.01999 = 0.01548 0.00039 0.00011 0.00067 AFIX 23 H16A 2 0.423592 0.878851 0.150124 11.00000 -1.20000 H16B 2 0.374004 0.829838 0.099295 11.00000 -1.20000 AFIX 0 C1 1 0.304472 0.790218 0.449188 11.00000 0.03592 0.04290 = 0.04311 -0.00047 -0.01522 -0.00099 C6 1 0.278799 0.725467 0.484686 11.00000 0.04096 0.04060 = 0.04509 -0.00004 -0.01623 0.00139 AFIX 43 H6 2 0.296939 0.671121 0.476094 11.00000 -1.20000 AFIX 0 C2 1 0.276571 0.870087 0.461766 11.00000 0.03182 0.04062 = 0.06334 -0.00066 -0.01431 -0.00314 C5 1 0.226697 0.739329 0.532796 11.00000 0.03766 0.05685 = 0.04992 0.00809 -0.01469 -0.00327 AFIX 43 H5 2 0.208945 0.694369 0.556706 11.00000 -1.20000 AFIX 0 C3 1 0.225909 0.883016 0.510207 11.00000 0.03566 0.04500 = 0.06927 -0.01211 -0.01669 0.00049 AFIX 43 H3 2 0.207956 0.937272 0.519288 11.00000 -1.20000 AFIX 0 C4 1 0.200663 0.817725 0.546019 11.00000 0.03015 0.07157 = 0.05265 -0.00703 -0.01127 0.00207 AFIX 43 H4 2 0.165710 0.827269 0.579343 11.00000 -1.20000 AFIX 0 C8 1 0.386481 0.704483 0.386801 11.00000 0.06710 0.05654 = 0.03766 -0.00400 -0.01188 0.01328 AFIX 137 H8A 2 0.421774 0.708064 0.351379 11.00000 -1.50000 H8B 2 0.340134 0.667528 0.378571 11.00000 -1.50000 H8C 2 0.418482 0.682952 0.420478 11.00000 -1.50000 AFIX 0 C7 1 0.268002 1.008851 0.427658 11.00000 0.04490 0.03777 = 0.14012 0.00807 0.00011 -0.00223 AFIX 137 H7A 2 0.291637 1.044765 0.396931 11.00000 -1.50000 H7B 2 0.279790 1.031686 0.467275 11.00000 -1.50000 H7C 2 0.208269 1.005160 0.422002 11.00000 -1.50000 AFIX 0 HKLF 4 REM exp_18_a.res in I4(1)/a REM R1 = 0.0511 for 2383 Fo > 4sig(Fo) and 0.0639 for all 3006 data REM 195 parameters refined using 0 restraints END WGHT 0.0691 4.1380 REM Highest difference peak 0.330, deepest hole -0.250, 1-sigma level 0.049 Q1 1 0.5043 0.7060 0.5681 11.00000 0.05 0.33 Q2 1 0.4573 0.7468 0.1830 11.00000 0.05 0.30 Q3 1 0.2758 1.0192 0.4801 11.00000 0.05 0.29 Q4 1 0.4169 0.7172 0.1431 11.00000 0.05 0.28 Q5 1 0.5051 0.6413 0.5713 11.00000 0.05 0.28 Q6 1 0.5390 0.6748 0.6011 11.00000 0.05 0.28 Q7 1 0.3875 0.7479 0.1801 11.00000 0.05 0.28 Q8 1 0.4685 0.6720 0.6034 11.00000 0.05 0.26 Q9 1 0.4229 0.7868 0.1452 11.00000 0.05 0.23 Q10 1 0.2910 0.9400 0.4645 11.00000 0.05 0.22 Q11 1 0.5150 0.5266 0.5821 11.00000 0.05 0.22 Q12 1 0.2701 0.8701 0.4916 11.00000 0.05 0.20 Q13 1 0.3555 0.7475 0.2616 11.00000 0.05 0.20 Q14 1 0.5023 0.5959 0.4911 11.00000 0.05 0.19 Q15 1 0.2871 0.7583 0.1758 11.00000 0.05 0.19 Q16 1 0.3012 0.8276 0.4591 11.00000 0.05 0.18 Q17 1 0.2167 0.8658 0.5406 11.00000 0.05 0.18 Q18 1 0.3116 1.0431 0.4450 11.00000 0.05 0.17 Q19 1 0.2142 0.7821 0.5328 11.00000 0.05 0.17 Q20 1 0.2075 1.0045 0.4364 11.00000 0.05 0.17 ; _shelx_res_checksum 16830 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_3-38_ethanol-tetradecane_3-fold_publ _database_code_depnum_ccdc_archive 'CCDC 1915300' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # end Validation Reply Form _audit_creation_date 2018-12-05 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C14 H16 O8, 0.43(C14 H30)' _chemical_formula_sum 'C20 H28.9 O8' _chemical_formula_weight 397.29 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system orthorhombic _space_group_IT_number 70 _space_group_name_H-M_alt 'F d d d' _space_group_name_Hall '-F 2uv 2vw' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+3/4, -y+3/4, z' '-x+3/4, y, -z+3/4' 'x, -y+3/4, -z+3/4' 'x, y+1/2, z+1/2' '-x+3/4, -y+5/4, z+1/2' '-x+3/4, y+1/2, -z+5/4' 'x, -y+5/4, -z+5/4' 'x+1/2, y, z+1/2' '-x+5/4, -y+3/4, z+1/2' '-x+5/4, y, -z+5/4' 'x+1/2, -y+3/4, -z+5/4' 'x+1/2, y+1/2, z' '-x+5/4, -y+5/4, z' '-x+5/4, y+1/2, -z+3/4' 'x+1/2, -y+5/4, -z+3/4' '-x, -y, -z' 'x-3/4, y-3/4, -z' 'x-3/4, -y, z-3/4' '-x, y-3/4, z-3/4' '-x, -y+1/2, -z+1/2' 'x-3/4, y-1/4, -z+1/2' 'x-3/4, -y+1/2, z-1/4' '-x, y-1/4, z-1/4' '-x+1/2, -y, -z+1/2' 'x-1/4, y-3/4, -z+1/2' 'x-1/4, -y, z-1/4' '-x+1/2, y-3/4, z-1/4' '-x+1/2, -y+1/2, -z' 'x-1/4, y-1/4, -z' 'x-1/4, -y+1/2, z-3/4' '-x+1/2, y-1/4, z-3/4' _cell_length_a 7.3713(11) _cell_length_b 22.951(4) _cell_length_c 23.585(4) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 3990.0(11) _cell_formula_units_Z 8 _cell_measurement_reflns_used 1322 _cell_measurement_temperature 200 _cell_measurement_theta_max 25.694 _cell_measurement_theta_min 2.477 _shelx_estimated_absorpt_T_max 0.995 _shelx_estimated_absorpt_T_min 0.989 _exptl_absorpt_coefficient_mu 0.102 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4564 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. wR2(int) was 0.0979 before and 0.0743 after correction. The Ratio of minimum to maximum transmission is 0.6123. The \l/2 correction factor is 0.00150.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.323 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 1703 _exptl_crystal_preparation ? _exptl_crystal_size_max 0.11 _exptl_crystal_size_mid 0.08 _exptl_crystal_size_min 0.05 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0818 _diffrn_reflns_av_unetI/netI 0.0561 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 0.998 _diffrn_reflns_limit_h_max 7 _diffrn_reflns_limit_h_min -9 _diffrn_reflns_limit_k_max 28 _diffrn_reflns_limit_k_min -28 _diffrn_reflns_limit_l_max 29 _diffrn_reflns_limit_l_min -27 _diffrn_reflns_number 8009 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 0.998 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.377 _diffrn_reflns_theta_min 2.477 _diffrn_ambient_temperature 200 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 0.998 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 628 _reflns_number_total 1028 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.332 _refine_diff_density_min -0.260 _refine_diff_density_rms 0.063 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.039 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 67 _refine_ls_number_reflns 1028 _refine_ls_number_restraints 3 _refine_ls_R_factor_all 0.1034 _refine_ls_R_factor_gt 0.0634 _refine_ls_restrained_S_all 1.044 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1230P)^2^+3.7672P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1830 _refine_ls_wR_factor_ref 0.2143 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H,H) groups At 1.5 times of: All O(H) groups 2. Rigid body (RIGU) restrains C7, C6 with sigma for 1-2 distances of 0.002 and sigma for 1-3 distances of 0.002 3. Others Fixed Sof: H4A(0.5) H4B(0.5) H3A(0.5) H3B(0.5) H1A(0.5) H1B(0.5) 4.a Secondary CH2 refined with riding coordinates: C4(H4A,H4B), C3(H3A,H3B), C1(H1A,H1B) 4.b Idealised tetrahedral OH refined as rotating group: O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O2 O 0.2324(3) 0.48604(10) 0.48359(9) 0.0519(7) Uani 1 1 d . . . . . O1 O -0.0263(3) 0.45076(11) 0.44997(9) 0.0514(8) Uani 1 1 d . . . . . C4 C 0.3750 0.3750 0.45035(13) 0.0267(9) Uani 1 2 d S T P . . C5 C 0.1395(3) 0.45206(12) 0.45024(10) 0.0302(7) Uani 1 1 d . . . . . C2 C 0.2539(3) 0.41363(11) 0.41262(9) 0.0272(7) Uani 1 1 d . . . . . C3 C 0.3750 0.45273(16) 0.3750 0.0293(9) Uani 1 2 d S T P . . C1 C 0.1335(5) 0.3750 0.3750 0.0272(8) Uani 1 2 d S T P . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O2 0.0281(11) 0.0662(16) 0.0614(14) -0.0346(11) 0.0023(10) -0.0012(11) O1 0.0195(11) 0.0728(17) 0.0618(14) -0.0323(12) 0.0020(9) 0.0017(10) C4 0.0192(18) 0.034(2) 0.0264(17) 0.000 0.000 -0.0021(15) C5 0.0221(13) 0.0362(16) 0.0324(14) -0.0024(10) -0.0003(10) -0.0012(12) C2 0.0165(12) 0.0329(14) 0.0322(13) -0.0017(10) 0.0007(10) 0.0007(11) C3 0.0226(18) 0.031(2) 0.0341(19) 0.000 -0.0004(14) 0.000 C1 0.0193(18) 0.0321(19) 0.0302(17) -0.0025(15) 0.000 0.000 _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O2 C5 1.302(3) . ? O1 C5 1.222(3) . ? C4 C2 1.541(3) . ? C4 C2 1.541(3) 2 ? C5 C2 1.508(3) . ? C2 C3 1.546(3) . ? C2 C1 1.536(3) . ? C3 C2 1.546(3) 3 ? C1 C2 1.536(3) 4 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C2 C4 C2 109.5(3) 2 . ? O2 C5 C2 114.3(2) . . ? O1 C5 O2 122.9(3) . . ? O1 C5 C2 122.8(2) . . ? C4 C2 C3 109.30(16) . . ? C5 C2 C4 108.70(19) . . ? C5 C2 C3 108.7(2) . . ? C5 C2 C1 110.8(2) . . ? C1 C2 C4 109.64(17) . . ? C1 C2 C3 109.69(16) . . ? C2 C3 C2 109.0(3) . 3 ? C2 C1 C2 109.5(3) 4 . ? _shelx_res_file ; pc_8_338_200k_fddd.res created by SHELXL-2014/7 TITL pc_8_338_200k_fddd_a.res in Fddd REM Old TITL PC_8_338_200K_Fddd in Fddd REM SHELXT solution in Fddd REM R1 0.266, Rweak 0.008, Alpha 0.030, Orientation as input REM Formula found by SHELXT: C7 O4 CELL 0.71073 7.3713 22.9506 23.5851 90 90 90 ZERR 8 0.0011 0.0038 0.0039 0 0 0 LATT 4 SYMM 0.75-X,0.75-Y,+Z SYMM 0.75-X,+Y,0.75-Z SYMM +X,0.75-Y,0.75-Z SFAC C H O UNIT 160 230.86 64 EQIV $1 -X,1-Y,1-Z RIGU 0.002 0.002 C7 C6 L.S. 50 PLAN 20 SIZE 0.11 0.08 0.05 TEMP -73.15 HTAB O2 O1_$1 BOND $H list 4 fmap 2 acta REM REM REM WGHT 0.123000 3.767200 FVAR 0.21648 O2 3 0.232440 0.486039 0.483586 11.00000 0.02813 0.06615 = 0.06137 -0.03464 0.00230 -0.00122 AFIX 147 H2 2 0.161253 0.504428 0.504875 11.00000 -1.50000 AFIX 0 O1 3 -0.026267 0.450756 0.449972 11.00000 0.01953 0.07276 = 0.06182 -0.03231 0.00199 0.00169 C4 1 0.375000 0.375000 0.450348 10.50000 0.01921 0.03436 = 0.02639 0.00000 0.00000 -0.00207 AFIX 23 H4A 2 0.451662 0.399803 0.474952 10.50000 -1.20000 H4B 2 0.298337 0.350196 0.474951 10.50000 -1.20000 AFIX 0 C5 1 0.139514 0.452057 0.450237 11.00000 0.02211 0.03623 = 0.03239 -0.00237 -0.00034 -0.00121 C2 1 0.253850 0.413628 0.412622 11.00000 0.01650 0.03290 = 0.03223 -0.00168 0.00071 0.00070 C3 1 0.375000 0.452728 0.375000 10.50000 0.02256 0.03116 = 0.03414 0.00000 -0.00042 0.00000 AFIX 23 H3A 2 0.451728 0.477993 0.399134 10.50000 -1.20000 H3B 2 0.298275 0.477994 0.350866 10.50000 -1.20000 AFIX 0 C1 1 0.133534 0.375000 0.375000 10.50000 0.01929 0.03211 = 0.03021 -0.00253 0.00000 0.00000 AFIX 23 H1A 2 0.054818 0.350274 0.399037 10.50000 -1.20000 H1B 2 0.054813 0.399724 0.350963 10.50000 -1.20000 AFIX 0 C7 1 0.375000 0.375000 0.610638 10.50000 0.22734 0.15391 = 0.11124 0.00000 0.00000 -0.04155 C6 1 0.206145 0.378764 0.646050 11.00000 0.22972 0.16679 = 0.11996 0.03044 0.00396 0.00099 HKLF 4 REM pc_8_338_200k_fddd_a.res in Fddd REM R1 = 0.0634 for 628 Fo > 4sig(Fo) and 0.1034 for all 1028 data REM 67 parameters refined using 3 restraints END WGHT 0.1229 3.7791 REM Highest difference peak 0.332, deepest hole -0.260, 1-sigma level 0.063 Q1 1 0.1751 0.3317 0.6730 11.00000 0.05 0.33 Q2 1 0.3560 0.4214 0.5783 11.00000 0.05 0.27 Q3 1 0.2662 0.4112 0.6206 11.00000 0.05 0.26 Q4 1 0.2436 0.4215 0.6796 11.00000 0.05 0.24 Q5 1 0.0011 0.4176 0.4829 11.00000 0.05 0.20 Q6 1 0.3750 0.3750 0.6851 10.50000 0.05 0.19 Q7 1 0.3139 0.4266 0.3989 11.00000 0.05 0.18 Q8 1 0.2067 0.4283 0.4245 11.00000 0.05 0.18 Q9 1 0.2796 0.4103 0.5714 11.00000 0.05 0.18 Q10 1 0.5165 0.4376 0.5680 11.00000 0.05 0.16 Q11 1 0.3217 0.4302 0.6420 11.00000 0.05 0.16 Q12 1 0.3379 0.4190 0.6516 11.00000 0.05 0.16 Q13 1 0.1559 0.4505 0.5062 11.00000 0.05 0.15 Q14 1 0.0850 0.4292 0.6495 11.00000 0.05 0.14 Q15 1 0.1277 0.4086 0.6849 11.00000 0.05 0.14 Q16 1 0.1107 0.4155 0.4893 11.00000 0.05 0.14 Q17 1 0.2890 0.3695 0.7227 11.00000 0.05 0.14 Q18 1 0.1250 0.4381 0.6250 10.50000 0.05 0.13 Q19 1 0.4763 0.4168 0.5993 11.00000 0.05 0.13 Q20 1 0.2495 0.4481 0.6420 11.00000 0.05 0.12 ; _shelx_res_checksum 26456 _olex2_submission_special_instructions 'No special instructions were received' # start Validation Reply Form _vrf_PLAT043_ADTA_3-38_ethanol-tetradecane_3-fold_publ ; PROBLEM: Calculated and Reported Mol. Weight Differ by .. 12.96 Check RESPONSE: Due to disorder, the tetradecane solvent molecule was modelled without riding H-atoms. However, H-atoms for this molecule were included in the refined formula_sum. ; _vrf_PLAT260_ADTA_3-38_ethanol-tetradecane_3-fold_publ ; PROBLEM: Large Average Ueq of Residue Including C6 0.168 Check RESPONSE: C6 was modelled as a tetradecane solvent molecule that was disordered in the 1-D voids in the crystal structure. ; ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_1-12_MeOH-Acetone_P-1_publ _database_code_depnum_ccdc_archive 'CCDC 1915305' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT043_TMA_1-12_MeOH-Acetone_P-1_publ ; PROBLEM: Calculated and Reported Mol. Weight Differ by .. 2.52 Check RESPONSE: Disordered solvent in large 1-D pores in the structure could not be resolved and was tentatively modelled at disordered H2O. H atoms for these molecules were only added to the unit cell atom count, but not refined as part of the structure. ; # end Validation Reply Form _audit_creation_date 2018-05-30 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6, 2.25(H2 O)' _chemical_formula_sum 'C9 H10.50 O8.25' _chemical_formula_weight 250.67 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system triclinic _space_group_IT_number 2 _space_group_name_H-M_alt 'P -1' _space_group_name_Hall '-P 1' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, -y, -z' _cell_length_a 3.5960(9) _cell_length_b 8.934(2) _cell_length_c 17.937(4) _cell_angle_alpha 77.839(7) _cell_angle_beta 86.729(7) _cell_angle_gamma 88.967(7) _cell_volume 562.4(2) _cell_formula_units_Z 2 _cell_measurement_reflns_used 903 _cell_measurement_temperature 100 _cell_measurement_theta_max 26.265 _cell_measurement_theta_min 2.326 _shelx_estimated_absorpt_T_max 0.988 _shelx_estimated_absorpt_T_min 0.971 _exptl_absorpt_coefficient_mu 0.134 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4925 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. wR2(int) was 0.0757 before and 0.0545 after correction. The Ratio of minimum to maximum transmission is 0.6607. The \l/2 correction factor is 0.00150. ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.480 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 261 _exptl_crystal_size_max 0.22 _exptl_crystal_size_mid 0.176 _exptl_crystal_size_min 0.09 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0655 _diffrn_reflns_av_unetI/netI 0.1317 _diffrn_reflns_Laue_measured_fraction_full 0.995 _diffrn_reflns_Laue_measured_fraction_max 0.987 _diffrn_reflns_limit_h_max 4 _diffrn_reflns_limit_h_min -3 _diffrn_reflns_limit_k_max 11 _diffrn_reflns_limit_k_min -11 _diffrn_reflns_limit_l_max 21 _diffrn_reflns_limit_l_min -22 _diffrn_reflns_number 5370 _diffrn_reflns_point_group_measured_fraction_full 0.995 _diffrn_reflns_point_group_measured_fraction_max 0.987 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.659 _diffrn_reflns_theta_min 2.327 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.995 _diffrn_measured_fraction_theta_max 0.987 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 1156 _reflns_number_total 2353 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.374 _refine_diff_density_min -0.380 _refine_diff_density_rms 0.086 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 0.916 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 196 _refine_ls_number_reflns 2353 _refine_ls_number_restraints 30 _refine_ls_R_factor_all 0.1470 _refine_ls_R_factor_gt 0.0676 _refine_ls_restrained_S_all 0.931 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0991P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1598 _refine_ls_wR_factor_ref 0.1898 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All O(H) groups, All O(H,H) groups 2. Uiso/Uaniso restraints and constraints Uanis(O1S) \\sim Ueq, Uanis(O2S) \\sim Ueq, Uanis(O3S) \\sim Ueq, Uanis(O4S) \\sim Ueq, Uanis(O5S) \\sim Ueq: with sigma of 0.01 and sigma for terminal atoms of 0.02 3. Others Fixed Sof: O5S(0.25) O3S(0.25) O2S(0.25) O1S(0.25) O4S(0.25) 4.a Free rotating group: O7(H7A,H7B) 4.b Aromatic/amide H refined with riding coordinates: C2(H2), C6(H6), C4(H4A) 4.c Idealised tetrahedral OH refined as rotating group: O1(H1), O5(H5), O4(H4) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O6 O 0.3009(8) 0.9394(3) 0.60273(16) 0.0274(7) Uani 1 1 d . . . . . O1 O 0.7608(8) 0.4231(3) 0.57737(15) 0.0299(7) Uani 1 1 d . . . . . H1 H 0.7978 0.3485 0.5561 0.045 Uiso 1 1 calc GR . . . . O2 O 1.0249(8) 0.2674(3) 0.67501(16) 0.0312(7) Uani 1 1 d . . . . . O5 O 0.3510(8) 1.0012(3) 0.71606(15) 0.0328(8) Uani 1 1 d . . . . . H5 H 0.2486 1.0826 0.6941 0.049 Uiso 1 1 calc GR . . . . O7 O 0.9844(9) 0.2043(3) 0.50979(16) 0.0313(8) Uani 1 1 d . . . . . H7A H 1.0863 0.1357 0.5427 0.047 Uiso 1 1 d G . . . . H7B H 0.8439 0.1624 0.4837 0.047 Uiso 1 1 d G . . . . O3 O 1.0305(8) 0.4242(3) 0.92410(15) 0.0313(7) Uani 1 1 d . . . . . O4 O 0.7563(8) 0.6464(3) 0.93541(15) 0.0327(8) Uani 1 1 d . . . . . H4 H 0.8417 0.6238 0.9790 0.049 Uiso 1 1 calc GR . . . . C7 C 0.8637(11) 0.3860(4) 0.6478(2) 0.0226(9) Uani 1 1 d . . . . . C9 C 0.3882(11) 0.9068(4) 0.6689(2) 0.0204(9) Uani 1 1 d . . . . . C3 C 0.7682(10) 0.5799(4) 0.8153(2) 0.0198(8) Uani 1 1 d . . . . . C2 C 0.8412(11) 0.4708(4) 0.7708(2) 0.0223(9) Uani 1 1 d . . . . . H2 H 0.9405 0.3736 0.7933 0.027 Uiso 1 1 calc R . . . . C1 C 0.7697(10) 0.5032(4) 0.6939(2) 0.0202(8) Uani 1 1 d . . . . . C6 C 0.6214(11) 0.6456(4) 0.6606(2) 0.0217(9) Uani 1 1 d . . . . . H6 H 0.5695 0.6677 0.6081 0.026 Uiso 1 1 calc R . . . . C5 C 0.5492(10) 0.7560(4) 0.7050(2) 0.0193(8) Uani 1 1 d . . . . . C8 C 0.8605(11) 0.5439(4) 0.8970(2) 0.0234(9) Uani 1 1 d . . . . . C4 C 0.6254(10) 0.7225(4) 0.7819(2) 0.0226(9) Uani 1 1 d . . . . . H4A H 0.5794 0.7975 0.8119 0.027 Uiso 1 1 calc R . . . . O5S O 1.148(12) 0.017(3) 0.9684(18) 0.111(9) Uani 0.25 1 d . U P A 5 O3S O 1.770(15) 0.038(3) 0.945(2) 0.144(10) Uani 0.25 1 d . U P B 3 O2S O 1.710(9) 0.070(2) 0.8737(14) 0.122(8) Uani 0.25 1 d . U P C 2 O1S O 2.194(11) 0.054(3) 0.8948(16) 0.144(9) Uani 0.25 1 d . U P D 1 O4S O 1.431(16) 0.021(3) 0.965(2) 0.138(12) Uani 0.25 1 d . U P E 4 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O6 0.0327(18) 0.0253(13) 0.0237(17) -0.0045(11) -0.0046(13) 0.0094(12) O1 0.0429(19) 0.0252(13) 0.0236(17) -0.0097(11) -0.0063(14) 0.0119(13) O2 0.0364(18) 0.0213(12) 0.0369(19) -0.0081(11) -0.0062(14) 0.0121(12) O5 0.045(2) 0.0214(13) 0.0345(18) -0.0089(11) -0.0129(14) 0.0128(12) O7 0.044(2) 0.0241(13) 0.0270(18) -0.0069(11) -0.0103(14) 0.0100(13) O3 0.0370(19) 0.0299(13) 0.0260(18) -0.0035(11) -0.0081(14) 0.0126(12) O4 0.042(2) 0.0320(14) 0.0264(18) -0.0095(12) -0.0099(15) 0.0132(13) C7 0.019(2) 0.0183(16) 0.030(2) -0.0043(14) 0.0001(18) 0.0020(15) C9 0.018(2) 0.0217(17) 0.022(2) -0.0062(15) 0.0022(18) 0.0004(15) C3 0.013(2) 0.0248(17) 0.021(2) -0.0036(14) -0.0004(16) 0.0004(15) C2 0.018(2) 0.0213(16) 0.027(2) -0.0025(15) -0.0004(17) 0.0020(15) C1 0.013(2) 0.0203(16) 0.027(2) -0.0031(14) 0.0002(17) -0.0008(14) C6 0.017(2) 0.0211(16) 0.026(2) -0.0044(15) -0.0007(17) 0.0004(15) C5 0.013(2) 0.0205(16) 0.023(2) -0.0023(14) 0.0003(17) -0.0008(14) C8 0.015(2) 0.0240(17) 0.031(3) -0.0056(16) 0.0019(18) 0.0028(15) C4 0.018(2) 0.0230(17) 0.029(2) -0.0097(15) -0.0003(18) 0.0016(15) O5S 0.135(18) 0.073(11) 0.135(18) -0.049(12) -0.003(14) 0.012(14) O3S 0.171(19) 0.076(12) 0.21(2) -0.071(14) -0.025(17) -0.004(14) O2S 0.197(19) 0.060(10) 0.125(15) -0.049(11) -0.029(14) -0.025(11) O1S 0.22(2) 0.107(13) 0.121(16) -0.071(13) 0.032(15) 0.003(14) O4S 0.15(2) 0.076(13) 0.19(2) -0.052(15) 0.005(18) 0.001(15) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O6 C9 1.220(4) . ? O1 H1 0.8400 . ? O1 C7 1.309(4) . ? O2 C7 1.220(4) . ? O5 H5 0.8400 . ? O5 C9 1.314(4) . ? O7 H7A 0.8500 . ? O7 H7B 0.8503 . ? O3 C8 1.243(4) . ? O4 H4 0.8400 . ? O4 C8 1.296(4) . ? C7 C1 1.488(5) . ? C9 C5 1.488(4) . ? C3 C2 1.397(5) . ? C3 C8 1.487(5) . ? C3 C4 1.391(5) . ? C2 H2 0.9500 . ? C2 C1 1.386(5) . ? C1 C6 1.397(5) . ? C6 H6 0.9500 . ? C6 C5 1.404(5) . ? C5 C4 1.392(5) . ? C4 H4A 0.9500 . ? O5S O5S 1.49(7) 2_757 ? O4S O4S 1.35(7) 2_857 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C7 O1 H1 109.5 . . ? C9 O5 H5 109.5 . . ? H7A O7 H7B 109.5 . . ? C8 O4 H4 109.5 . . ? O1 C7 C1 114.1(3) . . ? O2 C7 O1 124.6(3) . . ? O2 C7 C1 121.3(4) . . ? O6 C9 O5 123.6(3) . . ? O6 C9 C5 123.6(3) . . ? O5 C9 C5 112.8(3) . . ? C2 C3 C8 119.3(3) . . ? C4 C3 C2 119.6(3) . . ? C4 C3 C8 121.0(3) . . ? C3 C2 H2 119.8 . . ? C1 C2 C3 120.5(3) . . ? C1 C2 H2 119.8 . . ? C2 C1 C7 118.9(3) . . ? C2 C1 C6 119.9(3) . . ? C6 C1 C7 121.2(3) . . ? C1 C6 H6 120.1 . . ? C1 C6 C5 119.9(3) . . ? C5 C6 H6 120.1 . . ? C6 C5 C9 119.3(3) . . ? C4 C5 C9 121.0(3) . . ? C4 C5 C6 119.7(3) . . ? O3 C8 O4 124.1(4) . . ? O3 C8 C3 120.8(3) . . ? O4 C8 C3 115.1(3) . . ? C3 C4 C5 120.4(3) . . ? C3 C4 H4A 119.8 . . ? C5 C4 H4A 119.8 . . ? _shelx_res_file ; pc_ht_1_i112.res created by SHELXL-2014/7 TITL pc_ht_1_i112_a.res in P-1 REM Old TITL PC_HT_1_i112 in P-1 REM SHELXT solution in P-1 REM R1 0.197, Rweak 0.010, Alpha 0.050, Orientation as input REM Formula found by SHELXT: C9 O7 CELL 0.71073 3.596 8.9338 17.9368 77.839 86.729 88.967 ZERR 2 0.0009 0.0022 0.0044 0.007 0.007 0.007 LATT 1 SFAC C H O UNIT 18 21 16.5 ISOR 0.01 0.02 O1S O2S O3S O4S O5S L.S. 20 0 0 PLAN 20 SIZE 0.09 0.176 0.22 TEMP -173.15 BOND $H list 4 fmap 2 53 acta OMIT 0 1 2 REM REM REM WGHT 0.099100 FVAR 0.74760 O6 3 0.300912 0.939423 0.602728 11.00000 0.03270 0.02534 = 0.02372 -0.00449 -0.00457 0.00944 O1 3 0.760820 0.423097 0.577367 11.00000 0.04291 0.02523 = 0.02362 -0.00967 -0.00630 0.01190 AFIX 147 H1 2 0.797774 0.348515 0.556080 11.00000 -1.50000 AFIX 0 O2 3 1.024916 0.267408 0.675009 11.00000 0.03641 0.02132 = 0.03692 -0.00814 -0.00620 0.01212 O5 3 0.350969 1.001190 0.716058 11.00000 0.04466 0.02137 = 0.03446 -0.00889 -0.01290 0.01277 AFIX 147 H5 2 0.248616 1.082614 0.694135 11.00000 -1.50000 AFIX 6 O7 3 0.984415 0.204336 0.509786 11.00000 0.04389 0.02413 = 0.02702 -0.00688 -0.01027 0.00999 H7A 2 1.086264 0.135673 0.542671 11.00000 -1.50000 H7B 2 0.843892 0.162359 0.483681 11.00000 -1.50000 AFIX 0 O3 3 1.030453 0.424240 0.924099 11.00000 0.03701 0.02991 = 0.02604 -0.00346 -0.00814 0.01260 O4 3 0.756279 0.646409 0.935408 11.00000 0.04155 0.03203 = 0.02645 -0.00954 -0.00989 0.01324 AFIX 147 H4 2 0.841662 0.623797 0.979020 11.00000 -1.50000 AFIX 0 C7 1 0.863651 0.385993 0.647790 11.00000 0.01937 0.01828 = 0.02959 -0.00427 0.00014 0.00204 C9 1 0.388201 0.906804 0.668944 11.00000 0.01791 0.02170 = 0.02194 -0.00616 0.00223 0.00041 C3 1 0.768234 0.579852 0.815301 11.00000 0.01272 0.02484 = 0.02132 -0.00363 -0.00043 0.00039 C2 1 0.841188 0.470757 0.770763 11.00000 0.01778 0.02130 = 0.02650 -0.00248 -0.00037 0.00202 AFIX 43 H2 2 0.940546 0.373585 0.793341 11.00000 -1.20000 AFIX 0 C1 1 0.769700 0.503231 0.693897 11.00000 0.01289 0.02030 = 0.02658 -0.00314 0.00023 -0.00084 C6 1 0.621382 0.645644 0.660605 11.00000 0.01745 0.02114 = 0.02609 -0.00436 -0.00070 0.00036 AFIX 43 H6 2 0.569460 0.667742 0.608059 11.00000 -1.20000 AFIX 0 C5 1 0.549229 0.756028 0.704965 11.00000 0.01334 0.02047 = 0.02300 -0.00234 0.00032 -0.00077 C8 1 0.860506 0.543901 0.896954 11.00000 0.01477 0.02405 = 0.03077 -0.00561 0.00192 0.00277 C4 1 0.625350 0.722479 0.781938 11.00000 0.01794 0.02305 = 0.02859 -0.00972 -0.00029 0.00158 AFIX 43 H4A 2 0.579446 0.797464 0.811904 11.00000 -1.20000 AFIX 0 PART 5 O5S 3 1.147507 0.016808 0.968406 10.25000 0.13497 0.07270 = 0.13530 -0.04944 -0.00285 0.01187 PART 0 PART 3 O3S 3 1.769584 0.038046 0.944813 10.25000 0.17110 0.07628 = 0.20548 -0.07063 -0.02466 -0.00407 PART 0 PART 2 O2S 3 1.709858 0.070026 0.873692 10.25000 0.19691 0.06016 = 0.12542 -0.04895 -0.02872 -0.02457 PART 0 PART 1 O1S 3 2.194117 0.053677 0.894813 10.25000 0.22103 0.10700 = 0.12107 -0.07106 0.03250 0.00313 PART 0 PART 4 O4S 3 1.430710 0.021240 0.965023 10.25000 0.15253 0.07644 = 0.19317 -0.05220 0.00467 0.00083 HKLF 4 REM pc_ht_1_i112_a.res in P-1 REM R1 = 0.0676 for 1156 Fo > 4sig(Fo) and 0.1470 for all 2353 data REM 196 parameters refined using 30 restraints END WGHT 0.0991 0.0000 REM Highest difference peak 0.374, deepest hole -0.380, 1-sigma level 0.086 Q1 1 1.5332 0.0721 0.8937 11.00000 0.05 0.37 Q2 1 1.5118 0.0980 0.8842 11.00000 0.05 0.37 Q3 1 1.9226 0.0639 0.8888 11.00000 0.05 0.37 Q4 1 1.6660 0.0075 0.9834 11.00000 0.05 0.37 Q5 1 2.3314 -0.0331 0.9026 11.00000 0.05 0.37 Q6 1 1.8131 0.0757 0.8409 11.00000 0.05 0.30 Q7 1 0.8334 0.2799 0.5249 11.00000 0.05 0.30 Q8 1 1.2550 0.0646 1.0052 11.00000 0.05 0.28 Q9 1 0.8865 0.3200 0.6831 11.00000 0.05 0.28 Q10 1 1.4305 0.0000 1.0055 11.00000 0.05 0.28 Q11 1 1.4336 0.1536 0.8585 11.00000 0.05 0.27 Q12 1 0.9762 0.2849 0.6249 11.00000 0.05 0.26 Q13 1 0.5714 0.6233 0.5323 11.00000 0.05 0.25 Q14 1 0.9582 0.0402 0.9663 11.00000 0.05 0.25 Q15 1 2.0462 0.0746 0.8426 11.00000 0.05 0.25 Q16 1 1.9178 0.0045 0.9780 11.00000 0.05 0.25 Q17 1 1.2596 0.4891 0.9021 11.00000 0.05 0.24 Q18 1 0.1813 1.0251 0.6183 11.00000 0.05 0.23 Q19 1 0.8269 0.4434 0.6756 11.00000 0.05 0.23 Q20 1 1.1545 0.2635 0.5400 11.00000 0.05 0.23 ; _shelx_res_checksum 9699 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_7-38_dioxane-tetradecane_3-fold_publ _database_code_depnum_ccdc_archive 'CCDC 1915302' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT043_ADTA_7-38_dioxane-tetradecane_3-fold_publ ; PROBLEM: Calculated and Reported Mol. Weight Differ by .. 12.79 Check RESPONSE: Due to disorder, the tetradecane solvent molecule was modelled without riding H-atoms. However, H-atoms for this molecule were included in the refined formula_sum. ; # end Validation Reply Form _audit_creation_date 2018-12-06 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C14 H16 O8, 0.43(C14 H30)' _chemical_formula_sum 'C20.02 H28.86 O8' _chemical_formula_weight 397.50 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system tetragonal _space_group_IT_number 141 _space_group_name_H-M_alt 'I 41/a m d' _space_group_name_Hall '-I 4bd 2' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+1/2, -y, z+1/2' '-y+1/4, x+3/4, z+1/4' 'y+1/4, -x+1/4, z+3/4' '-x+1/2, y, -z+1/2' 'x, -y, -z' 'y+1/4, x+3/4, -z+1/4' '-y+1/4, -x+1/4, -z+3/4' 'x+1/2, y+1/2, z+1/2' '-x+1, -y+1/2, z+1' '-y+3/4, x+5/4, z+3/4' 'y+3/4, -x+3/4, z+5/4' '-x+1, y+1/2, -z+1' 'x+1/2, -y+1/2, -z+1/2' 'y+3/4, x+5/4, -z+3/4' '-y+3/4, -x+3/4, -z+5/4' '-x, -y, -z' 'x-1/2, y, -z-1/2' 'y-1/4, -x-3/4, -z-1/4' '-y-1/4, x-1/4, -z-3/4' 'x-1/2, -y, z-1/2' '-x, y, z' '-y-1/4, -x-3/4, z-1/4' 'y-1/4, x-1/4, z-3/4' '-x+1/2, -y+1/2, -z+1/2' 'x, y+1/2, -z' 'y+1/4, -x-1/4, -z+1/4' '-y+1/4, x+1/4, -z-1/4' 'x, -y+1/2, z' '-x+1/2, y+1/2, z+1/2' '-y+1/4, -x-1/4, z+1/4' 'y+1/4, x+1/4, z-1/4' _cell_length_a 16.429(3) _cell_length_b 16.429(3) _cell_length_c 7.3580(12) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 1986.0(7) _cell_formula_units_Z 4 _cell_measurement_reflns_used 2537 _cell_measurement_temperature 200 _cell_measurement_theta_max 25.936 _cell_measurement_theta_min 2.478 _shelx_estimated_absorpt_T_max 0.987 _shelx_estimated_absorpt_T_min 0.985 _exptl_absorpt_coefficient_mu 0.102 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4644 _exptl_absorpt_correction_type ? _exptl_absorpt_process_details ; Reflections not merged 7998 Corrected reflections written to file PC_8_638_200K_0m.hkl Estimated minimum and maximum transmission: 0.4644 0.7454 The ratio of these values is more reliable than their absolute values! Additional spherical absorption correction applied with mu*r = 0.2000 Lambda/2 correction factor = 0.00150 ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.329 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 852 _exptl_crystal_size_max 0.15 _exptl_crystal_size_mid 0.15 _exptl_crystal_size_min 0.13 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0598 _diffrn_reflns_av_unetI/netI 0.0356 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 1.000 _diffrn_reflns_limit_h_max 20 _diffrn_reflns_limit_h_min -20 _diffrn_reflns_limit_k_max 19 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 6 _diffrn_reflns_limit_l_min -9 _diffrn_reflns_number 7390 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 1.000 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.377 _diffrn_reflns_theta_min 2.479 _diffrn_ambient_temperature 200 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 407 _reflns_number_total 554 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'ShelXT (Sheldrick, 2015)' _refine_diff_density_max 0.241 _refine_diff_density_min -0.242 _refine_diff_density_rms 0.060 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.135 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 47 _refine_ls_number_reflns 554 _refine_ls_number_restraints 1 _refine_ls_R_factor_all 0.0842 _refine_ls_R_factor_gt 0.0650 _refine_ls_restrained_S_all 1.134 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0935P)^2^+3.5705P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1850 _refine_ls_wR_factor_ref 0.1993 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H,H) groups 2. Restrained distances O2-H2 0.82 with sigma of 0.02 3. Others Fixed Sof: H3A(0.5) H3B(0.5) H1A(0.25) H1B(0.25) 4.a Secondary CH2 refined with riding coordinates: C3(H3A,H3B), C1(H1A,H1B) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.65056(17) 0.2500 0.2242(3) 0.0489(10) Uani 1 2 d S T P . . O2 O 0.71998(17) 0.2500 0.4818(4) 0.0515(10) Uani 1 2 d DS T P . . C4 C 0.6520(2) 0.2500 0.3892(4) 0.0275(8) Uani 1 2 d S T P . . C2 C 0.57633(19) 0.2500 0.5038(4) 0.0235(8) Uani 1 2 d S T P . . C3 C 0.57611(14) 0.32611(14) 0.6250 0.0255(8) Uani 1 2 d S T P . . H3A H 0.6256 0.3266 0.7018 0.031 Uiso 0.5 1 calc R . . . . H3B H 0.5766 0.3756 0.5482 0.031 Uiso 0.5 1 calc R . . . . C1 C 0.5000 0.2500 0.3834(6) 0.0244(11) Uani 1 4 d S T P . . H1A H 0.5000 0.2988 0.3046 0.029 Uiso 0.5 2 calc RS T P . . H1B H 0.5000 0.2012 0.3046 0.029 Uiso 0.5 2 calc RS T P . . C5 C 0.7653(7) 0.0196(7) 0.560(3) 0.195(10) Uani 0.754(18) 1 d . . . . . H2 H 0.760(3) 0.2500 0.413(8) 0.10(2) Uiso 1 2 d DS T P . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0335(15) 0.095(3) 0.0180(13) 0.000 0.0020(11) 0.000 O2 0.0288(15) 0.102(3) 0.0241(14) 0.000 0.0009(12) 0.000 C4 0.0277(18) 0.0368(19) 0.0180(15) 0.000 -0.0002(13) 0.000 C2 0.0228(17) 0.0331(17) 0.0146(14) 0.000 0.0017(13) 0.000 C3 0.0304(12) 0.0304(12) 0.0157(14) 0.0004(9) -0.0004(9) -0.0038(14) C1 0.027(2) 0.033(3) 0.0129(19) 0.000 0.000 0.000 C5 0.190(14) 0.094(11) 0.30(3) -0.002(9) -0.085(16) -0.003(7) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C4 1.214(4) . ? O2 C4 1.309(4) . ? O2 H2 0.84(2) . ? C4 C2 1.502(4) . ? C2 C3 1.536(3) 27_566 ? C2 C3 1.536(3) . ? C2 C1 1.535(4) . ? C3 C2 1.536(3) 20_657 ? C3 H3A 0.9900 . ? C3 H3B 0.9900 . ? C1 C2 1.535(4) 10_554 ? C1 H1A 0.9900 . ? C1 H1B 0.9900 . ? C5 C5 1.09(3) 6_556 ? C5 C5 1.928(6) 12_554 ? C5 C5 1.928(6) 11_534 ? C5 C5 1.25(4) 16 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C4 O2 H2 111(5) . . ? O1 C4 O2 122.5(3) . . ? O1 C4 C2 123.1(3) . . ? O2 C4 C2 114.4(3) . . ? C4 C2 C3 109.15(18) . 27_566 ? C4 C2 C3 109.15(18) . . ? C4 C2 C1 110.6(3) . . ? C3 C2 C3 109.0(2) . 27_566 ? C1 C2 C3 109.45(16) . 27_566 ? C1 C2 C3 109.45(16) . . ? C2 C3 C2 109.9(3) 20_657 . ? C2 C3 H3A 109.7 . . ? C2 C3 H3A 109.7 20_657 . ? C2 C3 H3B 109.7 . . ? C2 C3 H3B 109.7 20_657 . ? H3A C3 H3B 108.2 . . ? C2 C1 C2 109.5(4) 10_554 . ? C2 C1 H1A 109.8 . . ? C2 C1 H1A 109.8 10_554 . ? C2 C1 H1B 109.8 10_554 . ? C2 C1 H1B 109.8 . . ? H1A C1 H1B 108.2 . . ? C5 C5 C5 110.3(17) 6_556 16 ? C5 C5 C5 125.2(17) 16 11_534 ? C5 C5 C5 37.6(15) 6_556 11_534 ? C5 C5 C5 127(2) 6_556 12_554 ? C5 C5 C5 155.5(7) 12_554 11_534 ? C5 C5 C5 32.1(12) 16 12_554 ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O2 H2 O1 0.84(2) 1.78(2) 2.612(4) 177(8) 5_655 _shelx_res_file ; pc_8_638_i41amd_200k.res created by SHELXL-2014/7 TITL pc_8_638_i41amd_200k_a.res in I4(1)/amd REM Old TITL PC_8_638_I41amd_200K in I4(1)/amd REM SHELXT solution in I4(1)/amd REM R1 0.258, Rweak 0.007, Alpha 0.019, Orientation as input REM Formula found by SHELXT: C7 O4 CELL 0.71073 16.429 16.429 7.358 90 90 90 ZERR 4 0.0026 0.0026 0.0012 0 0 0 LATT 2 SYMM 0.5-X,-Y,0.5+Z SYMM 0.25-Y,0.75+X,0.25+Z SYMM 0.25+Y,0.25-X,0.75+Z SYMM 0.5-X,+Y,0.5-Z SYMM +X,-Y,-Z SYMM 0.25+Y,0.75+X,0.25-Z SYMM 0.25-Y,0.25-X,0.75-Z SFAC C H O UNIT 80.07 115.43 32 EQIV $1 1.5-X,+Y,0.5-Z DFIX 0.82 O2 H2 L.S. 50 PLAN 20 SIZE 0.15 0.15 0.13 TEMP -73.15 HTAB O2 O1_$1 BOND $H list 4 fmap 2 53 acta REM REM REM WGHT 0.093500 3.570500 FVAR 0.43736 O1 3 0.650564 0.250000 0.224154 10.50000 0.03353 0.09506 = 0.01803 0.00000 0.00204 0.00000 O2 3 0.719977 0.250000 0.481802 10.50000 0.02880 0.10160 = 0.02411 0.00000 0.00087 0.00000 C4 1 0.651969 0.250000 0.389160 10.50000 0.02772 0.03679 = 0.01803 0.00000 -0.00016 0.00000 C2 1 0.576334 0.250000 0.503796 10.50000 0.02278 0.03311 = 0.01456 0.00000 0.00167 0.00000 C3 1 0.576113 0.326113 0.625000 10.50000 0.03041 0.03041 = 0.01574 0.00035 -0.00035 -0.00376 AFIX 23 H3A 2 0.625578 0.326636 0.701836 10.50000 -1.20000 H3B 2 0.576634 0.375578 0.548165 10.50000 -1.20000 AFIX 0 C1 1 0.500000 0.250000 0.383449 10.25000 0.02738 0.03274 = 0.01293 0.00000 0.00000 0.00000 AFIX 23 H1A 2 0.500000 0.298820 0.304578 10.25000 -1.20000 H1B 2 0.499999 0.201180 0.304578 10.25000 -1.20000 AFIX 0 C5 1 0.765299 0.019582 0.559946 0.75358 0.18987 0.09363 = 0.30284 -0.00155 -0.08522 -0.00284 H2 2 0.760297 0.250000 0.412634 10.50000 0.10418 HKLF 4 REM pc_8_638_i41amd_200k_a.res in I4(1)/amd REM R1 = 0.0650 for 407 Fo > 4sig(Fo) and 0.0842 for all 554 data REM 47 parameters refined using 1 restraints END WGHT 0.1038 3.5757 REM Highest difference peak 0.241, deepest hole -0.242, 1-sigma level 0.060 Q1 1 0.8494 0.0000 0.5000 10.50000 0.05 0.24 Q2 1 0.7703 0.0889 0.6223 11.00000 0.05 0.19 Q3 1 0.6106 0.2500 0.4597 10.50000 0.05 0.19 Q4 1 0.6955 0.2992 0.4300 11.00000 0.05 0.19 Q5 1 0.8479 0.1084 0.4032 11.00000 0.05 0.18 Q6 1 0.7480 0.0885 0.5076 11.00000 0.05 0.17 Q7 1 0.6678 0.1976 0.2823 11.00000 0.05 0.17 Q8 1 0.5000 0.3780 0.2980 10.50000 0.05 0.16 Q9 1 0.7692 0.0855 0.5035 11.00000 0.05 0.16 Q10 1 0.8451 0.0167 0.5762 11.00000 0.05 0.15 Q11 1 0.7298 0.2500 0.3050 10.50000 0.05 0.14 Q12 1 0.7240 0.2020 0.4091 11.00000 0.05 0.14 Q13 1 0.5467 0.2500 0.4447 10.50000 0.05 0.14 Q14 1 0.7909 0.0826 0.5033 11.00000 0.05 0.14 Q15 1 0.5000 0.2500 0.3180 10.25000 0.05 0.13 Q16 1 0.8503 0.0613 0.4986 11.00000 0.05 0.13 Q17 1 0.7869 0.2500 0.3619 10.50000 0.05 0.13 Q18 1 0.5000 0.3368 0.3963 10.50000 0.05 0.12 Q19 1 0.5943 0.2500 0.1470 10.50000 0.05 0.11 Q20 1 0.7644 0.0251 0.5156 11.00000 0.05 0.11 ; _shelx_res_checksum 58809 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_3-31_EtOH-cyclohexanone_publ _database_code_depnum_ccdc_archive 'CCDC 1915304' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT922_TMA_3-31_EtOH-cyclohexanone_publ ; PROBLEM: wR2 in the CIF and FCF Differ by ............... 0.0064 Check RESPONSE: The following WGHT scheme was used during refinement: 'w=1/[\s^2^(Fo^2^)+(0.1529P)^2^+3.7273P] where P=(Fo^2^+2Fc^2^)/3' ; # end Validation Reply Form _audit_creation_date 2018-05-30 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.18 svn.r3508 for OlexSys, GUI svn.r5497) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6, C6 H10 O' _chemical_formula_sum 'C15 H16 O7' _chemical_formula_weight 308.28 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 15 _space_group_name_H-M_alt 'C 1 2/c 1' _space_group_name_Hall '-C 2yc' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z+1/2' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y, z-1/2' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z-1/2' _cell_length_a 27.254(3) _cell_length_b 16.7260(16) _cell_length_c 6.7365(6) _cell_angle_alpha 90 _cell_angle_beta 100.207(3) _cell_angle_gamma 90 _cell_volume 3022.3(5) _cell_formula_units_Z 8 _cell_measurement_reflns_used 4792 _cell_measurement_temperature 100 _cell_measurement_theta_max 26.390 _cell_measurement_theta_min 2.436 _shelx_estimated_absorpt_T_max 0.995 _shelx_estimated_absorpt_T_min 0.991 _exptl_absorpt_coefficient_mu 0.109 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.5145 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. wR2(int) was 0.0862 before and 0.0623 after correction. The Ratio of minimum to maximum transmission is 0.6902. The \l/2 correction factor is 0.00150.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.355 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 1296 _exptl_crystal_size_max 0.085 _exptl_crystal_size_mid 0.058 _exptl_crystal_size_min 0.047 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0463 _diffrn_reflns_av_unetI/netI 0.0442 _diffrn_reflns_Laue_measured_fraction_full 0.999 _diffrn_reflns_Laue_measured_fraction_max 0.998 _diffrn_reflns_limit_h_max 34 _diffrn_reflns_limit_h_min -34 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 6 _diffrn_reflns_limit_l_min -8 _diffrn_reflns_number 16923 _diffrn_reflns_point_group_measured_fraction_full 0.999 _diffrn_reflns_point_group_measured_fraction_max 0.998 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.450 _diffrn_reflns_theta_min 1.435 _diffrn_ambient_temperature 100.0 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.999 _diffrn_measured_fraction_theta_max 0.998 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 2261 _reflns_number_total 3117 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.767 _refine_diff_density_min -0.485 _refine_diff_density_rms 0.082 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.065 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 257 _refine_ls_number_reflns 3117 _refine_ls_number_restraints 116 _refine_ls_R_factor_all 0.0943 _refine_ls_R_factor_gt 0.0731 _refine_ls_restrained_S_all 1.121 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1529P)^2^+3.7273P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.2250 _refine_ls_wR_factor_ref 0.2492 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups, All C(H,H) groups, All C(H,H,H,H) groups At 1.5 times of: All O(H) groups 2. Restrained distances C13-C14 = C15-C14 = C10-C15 = C11-C10 = C12-C11 = C16-C11 = C13-C12 = C17-C16 = C17-C18 = C19-C18 = C19-C10 1.52 with sigma of 0.02 O9-C19 1.23 with sigma of 0.02 C10-C18 2.56 with sigma of 0.04 C17-C11 2.56 with sigma of 0.04 C15-C13 2.56 with sigma of 0.04 C12-C10 2.56 with sigma of 0.04 C19-C17 2.56 with sigma of 0.04 C10-O9 \\sim O9-C18 with sigma of 0.02 3. Restrained planarity H5, O5, C8, O6, H6 with sigma of 0.01 4. Rigid body (RIGU) restrains C13, O8, C14, C15, C10, C12, O7, C11, C19, C16, C18, C17, O9 with sigma for 1-2 distances of 0.004 and sigma for 1-3 distances of 0.004 5. Others Fixed Sof: H5(0.5) H6(0.5) O8(0.6) O7(0.25) C14(0.75) C15(0.75) H15A(0.75) H15B(0.75) H10A(0.75) H10B(0.75) H11A(0.75) H11B(0.75) H11C(0.25) H11D(0.25) C12(0.75) H12A(0.75) H12B(0.75) C13(0.75) H13A(0.75) H13B(0.75) C18(0.25) H18A(0.25) H18B(0.25) C19(0.25) C17(0.25) H17A(0.25) H17B(0.25) C16(0.25) H16A(0.25) H16B(0.25) O9(0.15) 6.a Secondary CH2 refined with riding coordinates: C15(H15A,H15B), C10(H10A,H10B), C11(H11A,H11B), C11(H11C,H11D), C12(H12A, H12B), C13(H13A,H13B), C18(H18A,H18B), C17(H17A,H17B), C16(H16A,H16B) 6.b Aromatic/amide H refined with riding coordinates: C1(H1), C3(H3A), C5(H5A) 6.c Idealised tetrahedral OH refined as rotating group: O2(H2), O3(H3), O5(H5), O6(H6) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.30334(6) 0.32744(10) 0.3622(3) 0.0284(5) Uani 1 1 d . . . . . O2 O 0.23521(6) 0.39558(10) 0.2201(3) 0.0301(5) Uani 1 1 d . . . . . H2 H 0.2227 0.3496 0.2059 0.045 Uiso 1 1 calc GR . . . . O3 O 0.23591(6) 0.68559(10) 0.2090(3) 0.0299(5) Uani 1 1 d . . . . . H3 H 0.2230 0.7313 0.1981 0.045 Uiso 1 1 calc GR . . . . O4 O 0.30315(7) 0.75388(10) 0.3594(3) 0.0335(5) Uani 1 1 d . . . . . O5 O 0.45521(7) 0.60751(10) 0.6428(3) 0.0347(5) Uani 1 1 d . . . . . H5 H 0.4846 0.6004 0.7032 0.052 Uiso 0.5 1 calc GR . P . . O6 O 0.45582(7) 0.47351(10) 0.6382(3) 0.0295(5) Uani 1 1 d . . . . . H6 H 0.4852 0.4807 0.6986 0.044 Uiso 0.5 1 calc GR . P . . C1 C 0.28170(9) 0.54060(13) 0.3100(3) 0.0216(5) Uani 1 1 d . . . . . H1 H 0.2475 0.5405 0.2490 0.026 Uiso 1 1 calc R . . . . C2 C 0.30713(9) 0.61243(13) 0.3534(3) 0.0221(5) Uani 1 1 d . . . . . C3 C 0.35739(9) 0.61288(14) 0.4433(3) 0.0226(5) Uani 1 1 d . . . . . H3A H 0.3746 0.6621 0.4722 0.027 Uiso 1 1 calc R . . . . C4 C 0.38213(9) 0.54080(13) 0.4904(4) 0.0219(5) Uani 1 1 d . . . . . C5 C 0.35720(9) 0.46847(13) 0.4467(3) 0.0213(5) Uani 1 1 d . . . . . H5A H 0.3743 0.4193 0.4779 0.026 Uiso 1 1 calc R . . . . C6 C 0.30701(9) 0.46885(13) 0.3571(3) 0.0214(5) Uani 1 1 d . . . . . C7 C 0.28155(9) 0.69073(14) 0.3059(4) 0.0238(5) Uani 1 1 d . . . . . C8 C 0.43476(9) 0.54069(13) 0.5974(4) 0.0232(5) Uani 1 1 d . . . . . C9 C 0.28115(9) 0.39055(13) 0.3132(4) 0.0223(5) Uani 1 1 d . . . . . O8 O 0.3407(5) 0.0427(6) 0.466(2) 0.192(5) Uani 0.6 1 d . U P A 1 O7 O 0.4349(9) 0.2514(14) 0.800(3) 0.148(7) Uani 0.25 1 d . U P B 2 C14 C 0.3785(4) 0.0880(5) 0.4798(13) 0.113(2) Uani 0.75 1 d D U P A 1 C15 C 0.3999(4) 0.1277(5) 0.6726(13) 0.110(3) Uani 0.75 1 d D U P A 1 H15A H 0.3738 0.1318 0.7575 0.132 Uiso 0.75 1 calc R . P A 1 H15B H 0.4273 0.0943 0.7457 0.132 Uiso 0.75 1 calc R . P A 1 C10 C 0.4184(3) 0.2045(4) 0.6443(11) 0.131(2) Uani 1 1 d D U . . . H10A H 0.4441 0.2157 0.7646 0.157 Uiso 0.75 1 calc R . P B 1 H10B H 0.3906 0.2421 0.6501 0.157 Uiso 0.75 1 calc R . P B 1 C11 C 0.4398(3) 0.2281(5) 0.4715(11) 0.133(2) Uani 1 1 d D U . . . H11A H 0.4408 0.2872 0.4623 0.160 Uiso 0.75 1 calc R . P C 1 H11B H 0.4744 0.2078 0.4857 0.160 Uiso 0.75 1 calc R . P C 1 H11C H 0.4189 0.2727 0.4077 0.160 Uiso 0.25 1 calc R . P D 2 H11D H 0.4727 0.2518 0.5274 0.160 Uiso 0.25 1 calc R . P D 2 C12 C 0.4104(3) 0.1964(5) 0.2964(13) 0.105(2) Uani 0.75 1 d D U P A 1 H12A H 0.4285 0.2057 0.1834 0.126 Uiso 0.75 1 calc R . P A 1 H12B H 0.3794 0.2283 0.2679 0.126 Uiso 0.75 1 calc R . P A 1 C13 C 0.3957(4) 0.1106(5) 0.2901(13) 0.125(3) Uani 0.75 1 d D U P A 1 H13A H 0.3686 0.1012 0.1738 0.149 Uiso 0.75 1 calc R . P A 1 H13B H 0.4245 0.0769 0.2725 0.149 Uiso 0.75 1 calc R . P A 1 C18 C 0.4391(16) 0.0650(14) 0.481(3) 0.145(10) Uani 0.25 1 d D U P B 2 H18A H 0.4622 0.0211 0.5323 0.174 Uiso 0.25 1 calc R . P B 2 H18B H 0.4063 0.0394 0.4338 0.174 Uiso 0.25 1 calc R . P B 2 C19 C 0.4326(13) 0.1119(11) 0.664(3) 0.125(7) Uani 0.25 1 d D U P B 2 C17 C 0.456(2) 0.0924(14) 0.294(5) 0.195(18) Uani 0.25 1 d D U P B 2 H17A H 0.4910 0.0791 0.2953 0.233 Uiso 0.25 1 calc R . P B 2 H17B H 0.4348 0.0696 0.1723 0.233 Uiso 0.25 1 calc R . P B 2 C16 C 0.4483(11) 0.1775(14) 0.309(3) 0.113(6) Uani 0.25 1 d D U P B 2 H16A H 0.4778 0.2012 0.2641 0.135 Uiso 0.25 1 calc R . P B 2 H16B H 0.4198 0.1891 0.1991 0.135 Uiso 0.25 1 calc R . P B 2 O9 O 0.4587(13) 0.0919(17) 0.831(4) 0.157(10) Uani 0.15 1 d D U P B 2 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0285(9) 0.0199(8) 0.0351(10) 0.0012(7) 0.0008(7) -0.0001(7) O2 0.0242(9) 0.0233(9) 0.0395(11) 0.0018(7) -0.0032(8) -0.0031(7) O3 0.0255(9) 0.0225(9) 0.0387(10) -0.0004(7) -0.0027(8) 0.0044(7) O4 0.0303(10) 0.0213(9) 0.0437(11) -0.0036(7) -0.0074(8) 0.0029(7) O5 0.0268(9) 0.0271(10) 0.0462(12) -0.0054(8) -0.0051(8) -0.0020(7) O6 0.0242(9) 0.0274(9) 0.0349(10) 0.0034(7) 0.0000(7) 0.0029(7) C1 0.0208(11) 0.0254(12) 0.0182(11) -0.0003(9) 0.0020(9) 0.0005(9) C2 0.0237(12) 0.0214(11) 0.0204(11) -0.0006(8) 0.0021(9) 0.0011(9) C3 0.0257(12) 0.0210(11) 0.0206(11) -0.0013(8) 0.0026(9) 0.0002(9) C4 0.0219(12) 0.0241(11) 0.0196(11) -0.0005(8) 0.0035(9) 0.0010(9) C5 0.0247(12) 0.0204(11) 0.0188(11) -0.0002(8) 0.0041(9) 0.0019(9) C6 0.0234(12) 0.0223(12) 0.0186(11) 0.0001(8) 0.0042(9) -0.0003(9) C7 0.0255(12) 0.0224(12) 0.0231(12) -0.0016(9) 0.0030(9) 0.0005(9) C8 0.0239(12) 0.0219(11) 0.0234(12) -0.0015(9) 0.0031(9) -0.0005(9) C9 0.0236(12) 0.0215(12) 0.0217(11) 0.0008(8) 0.0040(9) -0.0003(9) O8 0.167(8) 0.131(8) 0.263(13) 0.014(6) -0.002(8) -0.014(6) O7 0.174(17) 0.154(12) 0.124(9) -0.034(9) 0.046(10) -0.028(12) C14 0.125(6) 0.086(5) 0.115(5) 0.017(4) -0.009(4) 0.000(4) C15 0.120(6) 0.111(5) 0.110(5) 0.014(4) 0.055(5) -0.006(4) C10 0.159(6) 0.132(5) 0.106(4) -0.004(4) 0.035(4) -0.020(5) C11 0.153(6) 0.136(5) 0.117(4) 0.020(4) 0.041(4) 0.000(4) C12 0.104(5) 0.105(5) 0.105(5) 0.023(4) 0.020(4) 0.028(4) C13 0.162(8) 0.102(5) 0.103(5) -0.009(4) 0.006(5) 0.042(5) C18 0.23(3) 0.117(11) 0.094(11) 0.010(8) 0.050(14) -0.011(12) C19 0.161(19) 0.133(8) 0.088(10) 0.004(7) 0.043(11) -0.034(8) C17 0.31(5) 0.159(12) 0.142(16) 0.035(9) 0.10(3) 0.017(13) C16 0.096(16) 0.145(11) 0.101(10) 0.019(8) 0.029(10) 0.006(11) O9 0.18(2) 0.195(19) 0.102(12) 0.016(10) 0.038(13) -0.028(16) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C9 1.232(3) . ? O2 H2 0.8400 . ? O2 C9 1.300(3) . ? O3 H3 0.8400 . ? O3 C7 1.301(3) . ? O4 C7 1.232(3) . ? O5 H5 0.8400 . ? O5 C8 1.262(3) . ? O6 H6 0.8400 . ? O6 C8 1.270(3) . ? C1 H1 0.9500 . ? C1 C2 1.392(3) . ? C1 C6 1.393(3) . ? C2 C3 1.396(3) . ? C2 C7 1.492(3) . ? C3 H3A 0.9500 . ? C3 C4 1.390(3) . ? C4 C5 1.393(3) . ? C4 C8 1.487(3) . ? C5 H5A 0.9500 . ? C5 C6 1.394(3) . ? C6 C9 1.492(3) . ? O8 C14 1.269(14) . ? O7 C10 1.32(2) . ? C14 C15 1.483(11) . ? C14 C13 1.485(11) . ? C15 H15A 0.9900 . ? C15 H15B 0.9900 . ? C15 C10 1.406(9) . ? C10 H10A 0.9900 . ? C10 H10B 0.9900 . ? C10 C11 1.447(8) . ? C10 C19 1.597(17) . ? C11 H11A 0.9900 . ? C11 H11B 0.9900 . ? C11 H11C 0.9900 . ? C11 H11D 0.9900 . ? C11 C12 1.408(10) . ? C11 C16 1.436(16) . ? C12 H12A 0.9900 . ? C12 H12B 0.9900 . ? C12 C13 1.489(11) . ? C13 H13A 0.9900 . ? C13 H13B 0.9900 . ? C18 H18A 0.9900 . ? C18 H18B 0.9900 . ? C18 C19 1.500(17) . ? C18 C17 1.479(18) . ? C19 O9 1.264(19) . ? C17 H17A 0.9900 . ? C17 H17B 0.9900 . ? C17 C16 1.443(18) . ? C16 H16A 0.9900 . ? C16 H16B 0.9900 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C9 O2 H2 109.5 . . ? C7 O3 H3 109.5 . . ? C8 O5 H5 109.5 . . ? C8 O6 H6 109.5 . . ? C2 C1 H1 120.4 . . ? C2 C1 C6 119.2(2) . . ? C6 C1 H1 120.4 . . ? C1 C2 C3 120.6(2) . . ? C1 C2 C7 121.1(2) . . ? C3 C2 C7 118.3(2) . . ? C2 C3 H3A 120.2 . . ? C4 C3 C2 119.5(2) . . ? C4 C3 H3A 120.2 . . ? C3 C4 C5 120.4(2) . . ? C3 C4 C8 119.9(2) . . ? C5 C4 C8 119.6(2) . . ? C4 C5 H5A 120.3 . . ? C4 C5 C6 119.5(2) . . ? C6 C5 H5A 120.3 . . ? C1 C6 C5 120.7(2) . . ? C1 C6 C9 120.9(2) . . ? C5 C6 C9 118.3(2) . . ? O3 C7 C2 114.7(2) . . ? O4 C7 O3 124.6(2) . . ? O4 C7 C2 120.6(2) . . ? O5 C8 O6 124.6(2) . . ? O5 C8 C4 117.6(2) . . ? O6 C8 C4 117.8(2) . . ? O1 C9 O2 124.7(2) . . ? O1 C9 C6 120.5(2) . . ? O2 C9 C6 114.8(2) . . ? O8 C14 C15 121.2(11) . . ? O8 C14 C13 117.7(11) . . ? C15 C14 C13 120.3(8) . . ? C14 C15 H15A 109.1 . . ? C14 C15 H15B 109.1 . . ? H15A C15 H15B 107.8 . . ? C10 C15 C14 112.7(7) . . ? C10 C15 H15A 109.1 . . ? C10 C15 H15B 109.1 . . ? O7 C10 C11 110.3(11) . . ? O7 C10 C19 117.7(16) . . ? C15 C10 H10A 106.2 . . ? C15 C10 H10B 106.2 . . ? C15 C10 C11 124.4(7) . . ? H10A C10 H10B 106.4 . . ? C11 C10 H10A 106.2 . . ? C11 C10 H10B 106.2 . . ? C11 C10 C19 101.8(10) . . ? C10 C11 H11A 110.0 . . ? C10 C11 H11B 110.0 . . ? C10 C11 H11C 105.7 . . ? C10 C11 H11D 105.7 . . ? H11A C11 H11B 108.3 . . ? H11C C11 H11D 106.1 . . ? C12 C11 C10 108.7(7) . . ? C12 C11 H11A 110.0 . . ? C12 C11 H11B 110.0 . . ? C16 C11 C10 126.6(12) . . ? C16 C11 H11C 105.7 . . ? C16 C11 H11D 105.7 . . ? C11 C12 H12A 107.3 . . ? C11 C12 H12B 107.3 . . ? C11 C12 C13 119.9(7) . . ? H12A C12 H12B 106.9 . . ? C13 C12 H12A 107.3 . . ? C13 C12 H12B 107.3 . . ? C14 C13 C12 110.2(7) . . ? C14 C13 H13A 109.6 . . ? C14 C13 H13B 109.6 . . ? C12 C13 H13A 109.6 . . ? C12 C13 H13B 109.6 . . ? H13A C13 H13B 108.1 . . ? H18A C18 H18B 105.8 . . ? C19 C18 H18A 105.0 . . ? C19 C18 H18B 105.0 . . ? C17 C18 H18A 105.0 . . ? C17 C18 H18B 105.0 . . ? C17 C18 C19 129(2) . . ? C18 C19 C10 120.1(17) . . ? O9 C19 C10 114.9(17) . . ? O9 C19 C18 118(2) . . ? C18 C17 H17A 111.7 . . ? C18 C17 H17B 111.7 . . ? H17A C17 H17B 109.4 . . ? C16 C17 C18 101(2) . . ? C16 C17 H17A 111.7 . . ? C16 C17 H17B 111.7 . . ? C11 C16 C17 132(2) . . ? C11 C16 H16A 104.1 . . ? C11 C16 H16B 104.1 . . ? C17 C16 H16A 104.1 . . ? C17 C16 H16B 104.1 . . ? H16A C16 H16B 105.5 . . ? _shelx_res_file ; pc_ht_1_i331_100k.res created by SHELXL-2014/7 TITL pc_ht_1_i331_100k_a.res in C2/c REM Old TITL PC_HT_1_i331_100K in C2/c REM SHELXT solution in C2/c REM R1 0.161, Rweak 0.002, Alpha 0.076, Orientation as input REM Formula found by SHELXT: C13 O6 CELL 0.71073 27.2542 16.726 6.7365 90 100.207 90 ZERR 8 0.0027 0.0016 0.0006 0 0.003 0 LATT 7 SYMM -X,+Y,0.5-Z SFAC C H O UNIT 120 128 56 DFIX 1.52 C13 C14 C15 C14 C10 C15 C11 C10 C12 C11 C16 C11 C13 C12 C17 C16 = C17 C18 C19 C18 C19 C10 DFIX 1.23 O9 C19 SADI C10 O9 O9 C18 DANG 2.56 C10 C18 DANG 2.56 C17 C11 DANG 2.56 C15 C13 DANG 2.56 C12 C10 DANG 2.56 C19 C17 FLAT 0.01 H5 O5 C8 O6 H6 RIGU C13 O8 C14 C15 C10 C12 O7 C11 C19 C16 C18 C17 O9 L.S. 50 PLAN 20 SIZE 0.047 0.058 0.085 TEMP -173.15 BOND $H list 4 fmap 2 acta OMIT 2 2 2 REM REM REM WGHT 0.152900 3.727300 FVAR 0.34623 O1 3 0.303341 0.327444 0.362172 11.00000 0.02845 0.01990 = 0.03507 0.00116 0.00079 -0.00006 O2 3 0.235206 0.395577 0.220105 11.00000 0.02421 0.02331 = 0.03945 0.00179 -0.00318 -0.00305 AFIX 147 H2 2 0.222665 0.349605 0.205942 11.00000 -1.50000 AFIX 0 O3 3 0.235912 0.685593 0.209000 11.00000 0.02552 0.02249 = 0.03870 -0.00044 -0.00267 0.00439 AFIX 147 H3 2 0.222962 0.731314 0.198055 11.00000 -1.50000 AFIX 0 O4 3 0.303148 0.753877 0.359435 11.00000 0.03029 0.02135 = 0.04369 -0.00364 -0.00742 0.00291 O5 3 0.455208 0.607510 0.642790 11.00000 0.02680 0.02706 = 0.04616 -0.00544 -0.00508 -0.00203 AFIX 147 H5 2 0.484589 0.600356 0.703196 10.50000 -1.50000 AFIX 0 O6 3 0.455822 0.473513 0.638170 11.00000 0.02421 0.02738 = 0.03485 0.00340 0.00002 0.00294 AFIX 147 H6 2 0.485194 0.480720 0.698610 10.50000 -1.50000 AFIX 0 C1 1 0.281698 0.540603 0.309981 11.00000 0.02082 0.02535 = 0.01817 -0.00028 0.00197 0.00050 AFIX 43 H1 2 0.247485 0.540528 0.248980 11.00000 -1.20000 AFIX 0 C2 1 0.307126 0.612426 0.353353 11.00000 0.02373 0.02144 = 0.02036 -0.00064 0.00212 0.00106 C3 1 0.357388 0.612881 0.443341 11.00000 0.02569 0.02102 = 0.02058 -0.00127 0.00261 0.00023 AFIX 43 H3A 2 0.374560 0.662106 0.472227 11.00000 -1.20000 AFIX 0 C4 1 0.382128 0.540804 0.490374 11.00000 0.02191 0.02411 = 0.01965 -0.00050 0.00351 0.00102 C5 1 0.357198 0.468472 0.446745 11.00000 0.02474 0.02037 = 0.01878 -0.00017 0.00406 0.00191 AFIX 43 H5A 2 0.374266 0.419288 0.477854 11.00000 -1.20000 AFIX 0 C6 1 0.307010 0.468846 0.357080 11.00000 0.02341 0.02228 = 0.01863 0.00006 0.00425 -0.00029 C7 1 0.281550 0.690733 0.305906 11.00000 0.02546 0.02238 = 0.02306 -0.00156 0.00300 0.00052 C8 1 0.434764 0.540694 0.597382 11.00000 0.02390 0.02192 = 0.02343 -0.00150 0.00307 -0.00050 C9 1 0.281151 0.390551 0.313238 11.00000 0.02364 0.02150 = 0.02166 0.00077 0.00401 -0.00028 PART 1 O8 3 0.340747 0.042662 0.466163 10.60000 0.16697 0.13104 = 0.26335 0.01410 -0.00183 -0.01403 PART 0 PART 2 O7 3 0.434902 0.251373 0.800016 10.25000 0.17401 0.15351 = 0.12435 -0.03425 0.04585 -0.02840 PART 0 PART 1 C14 1 0.378545 0.087960 0.479762 10.75000 0.12532 0.08633 = 0.11474 0.01727 -0.00937 0.00023 C15 1 0.399900 0.127704 0.672603 10.75000 0.12030 0.11134 = 0.11016 0.01359 0.05468 -0.00612 AFIX 23 H15A 2 0.373842 0.131788 0.757505 10.75000 -1.20000 H15B 2 0.427261 0.094312 0.745652 10.75000 -1.20000 AFIX 0 PART 0 C10 1 0.418396 0.204532 0.644270 11.00000 0.15896 0.13205 = 0.10613 -0.00362 0.03544 -0.02008 PART 1 AFIX 23 H10A 2 0.444056 0.215697 0.764597 10.75000 -1.20000 H10B 2 0.390614 0.242094 0.650096 10.75000 -1.20000 AFIX 0 PART 0 C11 1 0.439846 0.228147 0.471532 11.00000 0.15264 0.13624 = 0.11678 0.01985 0.04129 0.00000 PART 1 AFIX 23 H11A 2 0.440790 0.287183 0.462332 10.75000 -1.20000 H11B 2 0.474396 0.207765 0.485718 10.75000 -1.20000 AFIX 23 PART 0 PART 2 H11C 2 0.418874 0.272719 0.407745 10.25000 -1.20000 H11D 2 0.472694 0.251788 0.527429 10.25000 -1.20000 AFIX 0 PART 0 PART 1 C12 1 0.410444 0.196373 0.296396 10.75000 0.10426 0.10506 = 0.10515 0.02261 0.02027 0.02796 AFIX 23 H12A 2 0.428536 0.205664 0.183368 10.75000 -1.20000 H12B 2 0.379421 0.228342 0.267936 10.75000 -1.20000 AFIX 0 C13 1 0.395703 0.110576 0.290135 10.75000 0.16229 0.10186 = 0.10291 -0.00908 0.00575 0.04229 AFIX 23 H13A 2 0.368579 0.101161 0.173802 10.75000 -1.20000 H13B 2 0.424504 0.076927 0.272499 10.75000 -1.20000 AFIX 0 PART 0 PART 2 C18 1 0.439053 0.065017 0.480587 10.25000 0.23215 0.11713 = 0.09353 0.00977 0.04989 -0.01066 AFIX 23 H18A 2 0.462160 0.021089 0.532317 10.25000 -1.20000 H18B 2 0.406287 0.039430 0.433837 10.25000 -1.20000 AFIX 0 C19 1 0.432641 0.111920 0.663977 10.25000 0.16072 0.13290 = 0.08786 0.00361 0.04279 -0.03430 C17 1 0.455613 0.092443 0.294459 10.25000 0.30680 0.15854 = 0.14160 0.03543 0.10365 0.01699 AFIX 23 H17A 2 0.491035 0.079086 0.295272 10.25000 -1.20000 H17B 2 0.434775 0.069628 0.172261 10.25000 -1.20000 AFIX 0 C16 1 0.448250 0.177529 0.308601 10.25000 0.09635 0.14528 = 0.10066 0.01918 0.02880 0.00551 AFIX 23 H16A 2 0.477796 0.201180 0.264136 10.25000 -1.20000 H16B 2 0.419816 0.189147 0.199070 10.25000 -1.20000 AFIX 0 O9 3 0.458705 0.091883 0.830831 10.15000 0.17924 0.19544 = 0.10174 0.01619 0.03821 -0.02754 HKLF 4 REM pc_ht_1_i331_100k_a.res in C2/c REM R1 = 0.0731 for 2261 Fo > 4sig(Fo) and 0.0943 for all 3117 data REM 257 parameters refined using 116 restraints END WGHT 0.1533 3.5663 REM Highest difference peak 0.767, deepest hole -0.485, 1-sigma level 0.082 Q1 1 0.4703 0.0447 0.8392 11.00000 0.05 0.77 Q2 1 0.3549 0.0575 0.1430 11.00000 0.05 0.69 Q3 1 0.4477 0.0739 0.6839 11.00000 0.05 0.50 Q4 1 0.3731 0.1399 0.5916 11.00000 0.05 0.50 Q5 1 0.4591 0.1286 0.3685 11.00000 0.05 0.50 Q6 1 0.4253 0.1344 0.2901 11.00000 0.05 0.45 Q7 1 0.4524 0.0626 0.4867 11.00000 0.05 0.32 Q8 1 0.2977 0.6390 0.3317 11.00000 0.05 0.29 Q9 1 0.2957 0.4462 0.3322 11.00000 0.05 0.26 Q10 1 0.4859 0.0231 0.6188 11.00000 0.05 0.26 Q11 1 0.4916 0.0148 0.5107 11.00000 0.05 0.24 Q12 1 0.4705 0.0597 0.1726 11.00000 0.05 0.23 Q13 1 0.4066 0.2208 0.3770 11.00000 0.05 0.21 Q14 1 0.4119 0.0936 0.6188 11.00000 0.05 0.21 Q15 1 0.2821 0.7975 0.3727 11.00000 0.05 0.20 Q16 1 0.2977 0.5825 0.3138 11.00000 0.05 0.20 Q17 1 0.4098 0.5398 0.5180 11.00000 0.05 0.20 Q18 1 0.3418 0.1518 0.5142 11.00000 0.05 0.19 Q19 1 0.3827 0.0983 0.8748 11.00000 0.05 0.17 Q20 1 0.3820 0.1601 0.4415 11.00000 0.05 0.17 ; _shelx_res_checksum 17080 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_2-33_Pentane_Activated_C2c_200K_publ _database_code_depnum_ccdc_archive 'CCDC 1915307' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT602_TMA_2-33_Pentane_Activated_C2c_200K_publ ; PROBLEM: VERY LARGE Solvent Accessible VOID(S) in Structure ! Info RESPONSE: There are large 1-D voids in the crystal structure which contain no ordered electron density. ; _vrf_PLAT049_TMA_2-33_Pentane_Activated_C2c_200K_publ ; PROBLEM: Calculated Density Less Than 1.0 gcm-3 ......... 0.8872 Check RESPONSE: There are large 1-D voids in the crystal structure which contain no ordered electron density, accounting a crystal density < 1 g/cm3. ; # end Validation Reply Form _audit_creation_date 2018-05-21 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.18 svn.r3508 for OlexSys, GUI svn.r5497) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6' _chemical_formula_sum 'C9 H6 O6' _chemical_formula_weight 210.14 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 12 _space_group_name_H-M_alt 'C 1 2/m 1' _space_group_name_Hall '-C 2y' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z' '-x, -y, -z' 'x, -y, z' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z' _cell_length_a 26.075(2) _cell_length_b 16.4837(12) _cell_length_c 3.6749(3) _cell_angle_alpha 90 _cell_angle_beta 95.076(2) _cell_angle_gamma 90 _cell_volume 1573.3(2) _cell_formula_units_Z 4 _cell_measurement_reflns_used 3425 _cell_measurement_temperature 200 _cell_measurement_theta_max 26.318 _cell_measurement_theta_min 2.471 _shelx_estimated_absorpt_T_max 0.993 _shelx_estimated_absorpt_T_min 0.989 _exptl_absorpt_coefficient_mu 0.077 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4499 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2008/1 (Bruker,2008) was used for absorption correction. wR2(int) was 0.0920 before and 0.0644 after correction. The Ratio of minimum to maximum transmission is 0.6036. The \l/2 correction factor is 0.0015.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 0.887 _exptl_crystal_density_meas . _exptl_crystal_density_method ? _exptl_crystal_description hexagonal _exptl_crystal_F_000 432 _exptl_crystal_size_max 0.15 _exptl_crystal_size_mid 0.14 _exptl_crystal_size_min 0.09 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0430 _diffrn_reflns_av_unetI/netI 0.0357 _diffrn_reflns_Laue_measured_fraction_full 0.998 _diffrn_reflns_Laue_measured_fraction_max 0.994 _diffrn_reflns_limit_h_max 31 _diffrn_reflns_limit_h_min -32 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 3 _diffrn_reflns_limit_l_min -4 _diffrn_reflns_number 8938 _diffrn_reflns_point_group_measured_fraction_full 0.998 _diffrn_reflns_point_group_measured_fraction_max 0.994 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.686 _diffrn_reflns_theta_min 2.471 _diffrn_ambient_temperature 200 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.998 _diffrn_measured_fraction_theta_max 0.994 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 1324 _reflns_number_total 1723 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v7.68A (Bruker, 2009)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v7.68A (Bruker, 2009)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.209 _refine_diff_density_min -0.230 _refine_diff_density_rms 0.034 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.042 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 75 _refine_ls_number_reflns 1723 _refine_ls_number_restraints 0 _refine_ls_R_factor_all 0.0547 _refine_ls_R_factor_gt 0.0406 _refine_ls_restrained_S_all 1.042 _refine_ls_shift/su_max 0.001 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0633P)^2^+0.2903P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1101 _refine_ls_wR_factor_ref 0.1206 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All O(H) groups 2. Others Fixed Sof: H1(0.5) 3.a Aromatic/amide H refined with riding coordinates: C3(H3), C5(H5) 3.b Idealised tetrahedral OH refined as rotating group: O1(H1), O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.45408(4) 0.56771(6) 0.8196(3) 0.0555(3) Uani 1 1 d . . . . . H1 H 0.4848 0.5606 0.9035 0.083 Uiso 0.5 1 calc GR . . . . O2 O 0.30489(4) 0.28432(5) 0.2673(3) 0.0534(3) Uani 1 1 d . . . . . H2 H 0.2882 0.2439 0.1835 0.080 Uiso 1 1 calc GR . . . . O3 O 0.24020(3) 0.35097(6) -0.0406(3) 0.0502(3) Uani 1 1 d . . . . . C1 C 0.43358(6) 0.5000 0.7390(5) 0.0355(4) Uani 1 2 d S T P . . C2 C 0.38121(6) 0.5000 0.5399(4) 0.0337(4) Uani 1 2 d S T P . . C3 C 0.35689(5) 0.42658(7) 0.4486(3) 0.0346(3) Uani 1 1 d . . . . . H3 H 0.3736 0.3767 0.5117 0.042 Uiso 1 1 calc R . . . . C4 C 0.30786(4) 0.42702(7) 0.2640(3) 0.0341(3) Uani 1 1 d . . . . . C5 C 0.28330(6) 0.5000 0.1725(4) 0.0342(4) Uani 1 2 d S T P . . H5 H 0.2498 0.5000 0.0476 0.041 Uiso 1 2 calc RS T P . . C6 C 0.28199(5) 0.34918(7) 0.1551(3) 0.0373(3) Uani 1 1 d . . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0394(5) 0.0516(6) 0.0708(7) -0.0006(5) -0.0208(5) -0.0069(4) O2 0.0536(6) 0.0341(5) 0.0679(7) -0.0003(4) -0.0200(5) -0.0008(4) O3 0.0442(5) 0.0431(5) 0.0589(6) -0.0013(4) -0.0198(4) -0.0052(4) C1 0.0320(8) 0.0383(9) 0.0349(8) 0.000 -0.0039(7) 0.000 C2 0.0298(8) 0.0397(8) 0.0305(8) 0.000 -0.0041(6) 0.000 C3 0.0337(6) 0.0358(6) 0.0332(6) 0.0011(5) -0.0040(5) 0.0026(4) C4 0.0338(6) 0.0358(6) 0.0315(6) -0.0007(5) -0.0038(5) -0.0011(4) C5 0.0298(8) 0.0390(8) 0.0324(8) 0.000 -0.0058(6) 0.000 C6 0.0354(6) 0.0353(6) 0.0392(6) -0.0001(5) -0.0069(5) 0.0000(5) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 H1 0.8400 . ? O1 C1 1.2615(12) . ? O2 H2 0.8400 . ? O2 C6 1.2753(14) . ? O3 C6 1.2516(15) . ? C1 O1 1.2615(12) 6_565 ? C1 C2 1.491(2) . ? C2 C3 1.3934(14) . ? C2 C3 1.3934(14) 6_565 ? C3 H3 0.9500 . ? C3 C4 1.3933(16) . ? C4 C5 1.3901(14) . ? C4 C6 1.4878(16) . ? C5 C4 1.3902(14) 6_565 ? C5 H5 0.9500 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C1 O1 H1 109.5 . . ? C6 O2 H2 109.5 . . ? O1 C1 O1 124.45(15) . 6_565 ? O1 C1 C2 117.77(8) . . ? O1 C1 C2 117.77(8) 6_565 . ? C3 C2 C1 119.72(7) 6_565 . ? C3 C2 C1 119.71(7) . . ? C3 C2 C3 120.57(15) 6_565 . ? C2 C3 H3 120.3 . . ? C4 C3 C2 119.42(11) . . ? C4 C3 H3 120.3 . . ? C3 C4 C6 120.08(10) . . ? C5 C4 C3 120.36(11) . . ? C5 C4 C6 119.54(11) . . ? C4 C5 C4 119.86(15) . 6_565 ? C4 C5 H5 120.1 6_565 . ? C4 C5 H5 120.1 . . ? O2 C6 C4 116.60(10) . . ? O3 C6 O2 124.37(11) . . ? O3 C6 C4 119.02(10) . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O1 H1 O1 0.84 1.82 2.6325(17) 163.1 2_657 O2 H2 O3 0.84 1.79 2.6222(13) 171.5 7 _shelx_res_file ; pc_ht_1_i233_pentane_200k.res created by SHELXL-2014/7 TITL pc_ht_1_i233_pentane_200k_a.res in C2/m REM Old TITL PC_HT_1_i233_pentane_200K in C2/m #12 REM SHELXT solution in C2/m REM R1 0.169, Rweak 0.005, Alpha 0.043, Orientation as input REM Formula found by SHELXT: C9 O6 CELL 0.71073 26.0746 16.4837 3.6749 90 95.076 90 ZERR 4 0.002 0.0012 0.0003 0 0.002 0 LATT 7 SYMM -X,+Y,-Z SFAC C H O UNIT 36 24 24 EQIV $1 0.5-X,0.5-Y,-Z EQIV $2 1-X,+Y,2-Z L.S. 20 PLAN 20 SIZE 0.09 0.14 0.15 TEMP -73.15 HTAB O2 O3_$1 HTAB O1 O1_$2 BOND $H list 4 fmap 2 53 acta OMIT 2 0 0 OMIT 1 1 0 REM REM REM WGHT 0.063300 0.290300 FVAR 0.77772 O1 3 0.454080 0.567713 0.819642 11.00000 0.03943 0.05158 = 0.07077 -0.00063 -0.02080 -0.00687 AFIX 147 H1 2 0.484775 0.560625 0.903532 10.50000 -1.50000 AFIX 0 O2 3 0.304888 0.284317 0.267291 11.00000 0.05363 0.03410 = 0.06794 -0.00033 -0.02004 -0.00081 AFIX 147 H2 2 0.288152 0.243891 0.183450 11.00000 -1.50000 AFIX 0 O3 3 0.240202 0.350974 -0.040623 11.00000 0.04418 0.04315 = 0.05891 -0.00133 -0.01982 -0.00524 C1 1 0.433581 0.500000 0.738966 10.50000 0.03198 0.03833 = 0.03493 0.00000 -0.00392 0.00000 C2 1 0.381208 0.500000 0.539927 10.50000 0.02980 0.03970 = 0.03045 0.00000 -0.00414 0.00000 C3 1 0.356889 0.426581 0.448623 11.00000 0.03372 0.03579 = 0.03317 0.00106 -0.00404 0.00258 AFIX 43 H3 2 0.373592 0.376668 0.511717 11.00000 -1.20000 AFIX 0 C4 1 0.307861 0.427016 0.263983 11.00000 0.03382 0.03583 = 0.03148 -0.00066 -0.00382 -0.00112 C5 1 0.283300 0.500000 0.172457 10.50000 0.02978 0.03898 = 0.03236 0.00000 -0.00579 0.00000 AFIX 43 H5 2 0.249800 0.500000 0.047629 10.50000 -1.20000 AFIX 0 C6 1 0.281989 0.349182 0.155055 11.00000 0.03545 0.03535 = 0.03920 -0.00009 -0.00690 -0.00001 HKLF 4 REM pc_ht_1_i233_pentane_200k_a.res in C2/m REM R1 = 0.0406 for 1324 Fo > 4sig(Fo) and 0.0547 for all 1723 data REM 75 parameters refined using 0 restraints END WGHT 0.0633 0.2903 REM Highest difference peak 0.209, deepest hole -0.230, 1-sigma level 0.034 Q1 1 0.2989 0.3947 0.2079 11.00000 0.05 0.21 Q2 1 0.3991 0.5000 0.6060 10.50000 0.05 0.19 Q3 1 0.3212 0.4240 0.4076 11.00000 0.05 0.14 Q4 1 0.2247 0.3098 -0.1268 11.00000 0.05 0.14 Q5 1 0.2998 0.4595 0.1773 11.00000 0.05 0.12 Q6 1 0.3634 0.4603 0.5248 11.00000 0.05 0.12 Q7 1 0.3327 0.4274 0.2816 11.00000 0.05 0.12 Q8 1 0.4798 0.5796 0.9272 11.00000 0.05 0.12 Q9 1 0.3738 0.4672 0.4498 11.00000 0.05 0.11 Q10 1 0.4627 0.5404 0.6689 11.00000 0.05 0.10 Q11 1 0.3647 0.2597 0.4605 11.00000 0.05 0.09 Q12 1 0.4635 0.7458 0.8363 11.00000 0.05 0.09 Q13 1 0.3980 0.3356 0.5704 11.00000 0.05 0.08 Q14 1 0.4541 0.6724 0.8120 11.00000 0.05 0.08 Q15 1 0.4436 0.6594 0.7782 11.00000 0.05 0.08 Q16 1 0.3206 0.2583 0.5870 11.00000 0.05 0.08 Q17 1 0.2403 0.5000 0.1675 10.50000 0.05 0.08 Q18 1 0.1853 0.4180 -0.2345 11.00000 0.05 0.08 Q19 1 0.2789 0.4598 0.5449 11.00000 0.05 0.07 Q20 1 0.2346 0.4012 0.3600 11.00000 0.05 0.07 ; _shelx_res_checksum 98835 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_2-33_Pentane_Activated_C2c_350K_publ _database_code_depnum_ccdc_archive 'CCDC 1915306' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT602_TMA_2-33_Pentane_Activated_C2c_350K_publ ; PROBLEM: VERY LARGE Solvent Accessible VOID(S) in Structure ! Info RESPONSE: There are large 1-D voids in the crystal structure which contain no ordered electron density. ; _vrf_PLAT049_TMA_2-33_Pentane_Activated_C2c_350K_publ ; PROBLEM: Calculated Density Less Than 1.0 gcm-3 ......... 0.8645 Check RESPONSE: There are large 1-D voids in the crystal structure which contain no ordered electron density, accounting a crystal density < 1 g/cm3. ; # end Validation Reply Form _audit_creation_date 2018-05-21 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.18 svn.r3508 for OlexSys, GUI svn.r5497) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6' _chemical_formula_sum 'C9 H6 O6' _chemical_formula_weight 210.14 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 12 _space_group_name_H-M_alt 'C 1 2/m 1' _space_group_name_Hall '-C 2y' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z' '-x, -y, -z' 'x, -y, z' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z' _cell_length_a 26.240(5) _cell_length_b 16.529(3) _cell_length_c 3.7452(7) _cell_angle_alpha 90 _cell_angle_beta 96.283(6) _cell_angle_gamma 90 _cell_volume 1614.6(5) _cell_formula_units_Z 4 _cell_measurement_reflns_used 3253 _cell_measurement_temperature 350 _cell_measurement_theta_max 25.796 _cell_measurement_theta_min 2.465 _shelx_estimated_absorpt_T_max 0.993 _shelx_estimated_absorpt_T_min 0.989 _exptl_absorpt_coefficient_mu 0.075 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4607 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2008/1 (Bruker,2008) was used for absorption correction. wR2(int) was 0.0824 before and 0.0597 after correction. The Ratio of minimum to maximum transmission is 0.6181. The \l/2 correction factor is 0.0015.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 0.864 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description hexagonal _exptl_crystal_F_000 432 _exptl_crystal_size_max 0.15 _exptl_crystal_size_mid 0.14 _exptl_crystal_size_min 0.09 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0379 _diffrn_reflns_av_unetI/netI 0.0327 _diffrn_reflns_Laue_measured_fraction_full 0.998 _diffrn_reflns_Laue_measured_fraction_max 0.997 _diffrn_reflns_limit_h_max 31 _diffrn_reflns_limit_h_min -32 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 3 _diffrn_reflns_limit_l_min -4 _diffrn_reflns_number 9783 _diffrn_reflns_point_group_measured_fraction_full 0.998 _diffrn_reflns_point_group_measured_fraction_max 0.997 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.472 _diffrn_reflns_theta_min 2.464 _diffrn_ambient_temperature 350 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.998 _diffrn_measured_fraction_theta_max 0.997 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 1183 _reflns_number_total 1731 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v7.68A (Bruker, 2009)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v7.68A (Bruker, 2009)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution ? _refine_diff_density_max 0.148 _refine_diff_density_min -0.158 _refine_diff_density_rms 0.026 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.020 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 75 _refine_ls_number_reflns 1731 _refine_ls_number_restraints 0 _refine_ls_R_factor_all 0.0622 _refine_ls_R_factor_gt 0.0423 _refine_ls_restrained_S_all 1.020 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0654P)^2^+0.2603P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1190 _refine_ls_wR_factor_ref 0.1342 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All O(H) groups 2. Others Fixed Sof: H1(0.5) 3.a Aromatic/amide H refined with riding coordinates: C3(H3), C5(H5) 3.b Idealised tetrahedral OH refined as rotating group: O1(H1), O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.45376(4) 0.56714(6) 0.8205(4) 0.0937(5) Uani 1 1 d . . . . . H1 H 0.4837 0.5600 0.9032 0.141 Uiso 0.5 1 calc GR . . . . O2 O 0.30475(4) 0.28517(6) 0.2582(4) 0.0960(4) Uani 1 1 d . . . . . H2 H 0.2893 0.2462 0.1635 0.144 Uiso 1 1 calc GR . . . . O3 O 0.23986(4) 0.35158(7) -0.0385(3) 0.0904(4) Uani 1 1 d . . . . . C1 C 0.43317(7) 0.5000 0.7387(5) 0.0624(5) Uani 1 2 d S T P . . C2 C 0.38097(7) 0.5000 0.5387(5) 0.0574(5) Uani 1 2 d S T P . . C3 C 0.35674(5) 0.42702(8) 0.4468(4) 0.0602(4) Uani 1 1 d . . . . . H3 H 0.3731 0.3783 0.5091 0.072 Uiso 1 1 calc R . . . . C4 C 0.30778(5) 0.42719(8) 0.2608(4) 0.0590(4) Uani 1 1 d . . . . . C5 C 0.28344(7) 0.5000 0.1686(5) 0.0597(5) Uani 1 2 d S T P . . H5 H 0.2507 0.5000 0.0448 0.072 Uiso 1 2 calc RS T P . . C6 C 0.28211(5) 0.34957(8) 0.1527(4) 0.0662(4) Uani 1 1 d . . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0638(7) 0.0787(8) 0.1280(11) -0.0011(6) -0.0373(7) -0.0084(5) O2 0.0882(8) 0.0564(6) 0.1315(10) -0.0011(6) -0.0416(7) -0.0019(5) O3 0.0746(7) 0.0678(7) 0.1175(9) -0.0018(6) -0.0405(6) -0.0080(5) C1 0.0518(10) 0.0611(11) 0.0700(12) 0.000 -0.0120(9) 0.000 C2 0.0482(9) 0.0614(10) 0.0592(10) 0.000 -0.0094(8) 0.000 C3 0.0544(7) 0.0581(7) 0.0644(8) 0.0009(6) -0.0102(6) 0.0038(6) C4 0.0544(7) 0.0577(8) 0.0613(8) -0.0011(6) -0.0101(6) -0.0025(6) C5 0.0495(9) 0.0633(11) 0.0621(11) 0.000 -0.0128(8) 0.000 C6 0.0595(8) 0.0567(8) 0.0771(9) -0.0008(7) -0.0170(7) -0.0006(6) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 H1 0.8200 . ? O1 C1 1.2574(13) . ? O2 H2 0.8200 . ? O2 C6 1.2613(16) . ? O3 C6 1.2528(16) . ? C1 O1 1.2574(13) 6_565 ? C1 C2 1.487(2) . ? C2 C3 1.3892(16) . ? C2 C3 1.3892(16) 6_565 ? C3 H3 0.9300 . ? C3 C4 1.3929(18) . ? C4 C5 1.3882(15) . ? C4 C6 1.4845(18) . ? C5 C4 1.3882(16) 6_565 ? C5 H5 0.9300 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C1 O1 H1 109.5 . . ? C6 O2 H2 109.5 . . ? O1 C1 O1 123.91(17) . 6_565 ? O1 C1 C2 118.04(9) 6_565 . ? O1 C1 C2 118.04(9) . . ? C3 C2 C1 119.74(8) . . ? C3 C2 C1 119.74(8) 6_565 . ? C3 C2 C3 120.52(16) 6_565 . ? C2 C3 H3 120.2 . . ? C2 C3 C4 119.63(13) . . ? C4 C3 H3 120.2 . . ? C3 C4 C6 120.06(12) . . ? C5 C4 C3 120.00(13) . . ? C5 C4 C6 119.92(12) . . ? C4 C5 C4 120.22(16) . 6_565 ? C4 C5 H5 119.9 . . ? C4 C5 H5 119.9 6_565 . ? O2 C6 C4 117.38(12) . . ? O3 C6 O2 123.95(13) . . ? O3 C6 C4 118.66(11) . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O1 H1 O1 0.82 1.85 2.642(2) 163.4 2_657 O2 H2 O3 0.82 1.83 2.6354(15) 168.0 7 _shelx_res_file ; pc_ht_1_i233_pentane_activated.res created by SHELXL-2014/7 TITL PC_HT_1_i233_pentane_activated.res in C2/m REM Old TITL PC_HT_1_i233_pentane_200K in C2/m #12 REM SHELXT solution in C2/m REM R1 0.169, Rweak 0.005, Alpha 0.043, Orientation as input REM Formula found by SHELXT: C9 O6 CELL 0.71073 26.24 16.5291 3.7452 90 96.283 90 ZERR 8 0.0053 0.0033 0.0007 0 0.006 0 LATT 7 SYMM -X,+Y,-Z SFAC C H O UNIT 36 24 24 EQIV $1 0.5-X,0.5-Y,-Z EQIV $2 1-X,+Y,2-Z L.S. 20 PLAN 20 SIZE 0.09 0.14 0.15 TEMP 76.85 HTAB O2 O3_$1 HTAB O1 O1_$2 BOND $H list 4 fmap 2 53 acta OMIT 2 0 0 OMIT 1 1 0 REM REM REM WGHT 0.065400 0.260300 FVAR 0.81303 O1 3 0.453757 0.567137 0.820539 11.00000 0.06382 0.07869 = 0.12802 -0.00112 -0.03729 -0.00839 AFIX 147 H1 2 0.483663 0.560018 0.903233 10.50000 -1.50000 AFIX 0 O2 3 0.304750 0.285166 0.258195 11.00000 0.08823 0.05637 = 0.13150 -0.00112 -0.04158 -0.00191 AFIX 147 H2 2 0.289315 0.246241 0.163468 11.00000 -1.50000 AFIX 0 O3 3 0.239856 0.351584 -0.038540 11.00000 0.07458 0.06776 = 0.11746 -0.00177 -0.04054 -0.00799 C1 1 0.433166 0.500000 0.738716 10.50000 0.05180 0.06113 = 0.07003 0.00000 -0.01203 0.00000 C2 1 0.380972 0.500000 0.538747 10.50000 0.04825 0.06138 = 0.05916 0.00000 -0.00942 0.00000 C3 1 0.356743 0.427024 0.446782 11.00000 0.05444 0.05811 = 0.06443 0.00087 -0.01024 0.00381 AFIX 43 H3 2 0.373122 0.378334 0.509070 11.00000 -1.20000 AFIX 0 C4 1 0.307779 0.427187 0.260756 11.00000 0.05439 0.05774 = 0.06133 -0.00110 -0.01010 -0.00253 C5 1 0.283442 0.500000 0.168647 10.50000 0.04947 0.06335 = 0.06208 0.00000 -0.01284 0.00000 AFIX 43 H5 2 0.250725 0.499999 0.044820 10.50000 -1.20000 AFIX 0 C6 1 0.282108 0.349573 0.152722 11.00000 0.05949 0.05666 = 0.07714 -0.00082 -0.01701 -0.00056 HKLF 4 REM PC_HT_1_i233_pentane_activated.res in C2/m REM R1 = 0.0423 for 1183 Fo > 4sig(Fo) and 0.0622 for all 1731 data REM 75 parameters refined using 0 restraints END WGHT 0.0666 0.2507 REM Highest difference peak 0.148, deepest hole -0.158, 1-sigma level 0.026 Q1 1 0.2224 0.3081 -0.1193 11.00000 0.05 0.15 Q2 1 0.2982 0.3999 0.2112 11.00000 0.05 0.14 Q3 1 0.3937 0.5000 0.6157 10.50000 0.05 0.13 Q4 1 0.4643 0.5406 0.6445 11.00000 0.05 0.12 Q5 1 0.4821 0.5770 0.9402 11.00000 0.05 0.12 Q6 1 0.3015 0.4557 0.2095 11.00000 0.05 0.10 Q7 1 0.3799 0.3563 0.5524 11.00000 0.05 0.09 Q8 1 0.4398 0.6568 0.7394 11.00000 0.05 0.09 Q9 1 0.3787 0.5190 0.4574 11.00000 0.05 0.08 Q10 1 0.2255 0.3528 0.1898 11.00000 0.05 0.08 Q11 1 0.2474 0.5000 -0.0716 10.50000 0.05 0.07 Q12 1 0.4499 0.5571 0.8747 11.00000 0.05 0.06 Q13 1 0.4574 0.6688 0.8338 11.00000 0.05 0.06 Q14 1 0.2081 0.4202 -0.1584 11.00000 0.05 0.06 Q15 1 0.3485 0.5000 0.7476 10.50000 0.05 0.06 Q16 1 0.2124 0.4297 -0.1282 11.00000 0.05 0.06 Q17 1 0.2280 0.5000 0.1964 10.50000 0.05 0.06 Q18 1 0.4430 0.5400 0.9939 11.00000 0.05 0.06 Q19 1 0.3567 0.5000 0.8557 10.50000 0.05 0.05 Q20 1 0.3571 0.2750 0.4645 11.00000 0.05 0.05 ; _shelx_res_checksum 38008 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_7-35_Dioxane-1-3-dimethoxybenzene_C2m_100K_publ _database_code_depnum_ccdc_archive 'CCDC 1915308' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2019-02-05 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O0, 7.5(O)' _chemical_formula_sum 'C9 H6 O13.50' _chemical_formula_weight 330.14 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 12 _space_group_name_H-M_alt 'C 1 2/m 1' _space_group_name_Hall '-C 2y' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z' '-x, -y, -z' 'x, -y, z' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z' _cell_length_a 25.869(4) _cell_length_b 16.419(3) _cell_length_c 3.6060(6) _cell_angle_alpha 90 _cell_angle_beta 93.617(4) _cell_angle_gamma 90 _cell_volume 1528.6(4) _cell_formula_units_Z 4 _cell_measurement_reflns_used 5675 _cell_measurement_temperature 100 _cell_measurement_theta_max 27.495 _cell_measurement_theta_min 2.481 _shelx_estimated_absorpt_T_max 0.987 _shelx_estimated_absorpt_T_min 0.976 _exptl_absorpt_coefficient_mu 0.143 _exptl_absorpt_correction_T_max 0.745552 _exptl_absorpt_correction_T_min 0.461222 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; TWINABS-2012/1 (Bruker,2012) was used for absorption correction. Final HKLF 4 output contains 16286 reflections, Rint = 0.0561 (11151 with I > 3sig(I), Rint = 0.0547) ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.435 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 672 _exptl_crystal_size_max 0.17 _exptl_crystal_size_mid 0.11 _exptl_crystal_size_min 0.09 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents ? _diffrn_reflns_av_unetI/netI 0.0431 _diffrn_reflns_Laue_measured_fraction_full 0.993 _diffrn_reflns_Laue_measured_fraction_max 0.994 _diffrn_reflns_limit_h_max 32 _diffrn_reflns_limit_h_min -31 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min 0 _diffrn_reflns_limit_l_max 4 _diffrn_reflns_limit_l_min 0 _diffrn_reflns_number 1664 _diffrn_reflns_point_group_measured_fraction_full 0.993 _diffrn_reflns_point_group_measured_fraction_max 0.994 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.370 _diffrn_reflns_theta_min 2.481 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.993 _diffrn_measured_fraction_theta_max 0.994 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 1533 _reflns_number_total 1664 _reflns_special_details ; _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution ? _refine_diff_density_max 0.317 _refine_diff_density_min -0.415 _refine_diff_density_rms 0.072 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.070 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 137 _refine_ls_number_reflns 1664 _refine_ls_number_restraints 1 _refine_ls_R_factor_all 0.0727 _refine_ls_R_factor_gt 0.0688 _refine_ls_restrained_S_all 1.069 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1231P)^2^+2.1499P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1992 _refine_ls_wR_factor_ref 0.2049 _refine_special_details ; Refined as a 2-component twin. ; _olex2_refinement_description ; 1. Twinned data refinement Scales: 0.930(4) 0.070(4) 2. Fixed Uiso At 1.2 times of: All C(H) groups 3. Restrained distances O2-H2 0.83 with sigma of 0.01 4. Others Fixed Sof: O1S(0.25) O9S(0.5) O2S(0.25) O8S(0.5) O3S(0.25) O6S(0.25) O15S(0.25) O10S(0.25) O7S(0.25) O5S(0.25) H3(0.5) O4S(0.25) O13S(0.125) O14S(0.125) O11S(0.125) O12S(0.125) 5.a Aromatic/amide H refined with riding coordinates: C3(H3A), C1(H1) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.75944(6) 0.65018(9) 1.0312(4) 0.0304(5) Uani 1 1 d . . . . . O2 O 0.69473(6) 0.71677(9) 0.7191(4) 0.0323(5) Uani 1 1 d D . . . . O3 O 0.54555(7) 0.43169(10) 0.1814(5) 0.0364(5) Uani 1 1 d . . . . . C6 C 0.71836(8) 0.65127(11) 0.8362(5) 0.0229(5) Uani 1 1 d . . . . . C2 C 0.69222(8) 0.57340(11) 0.7248(5) 0.0217(5) Uani 1 1 d . . . . . C3 C 0.64285(8) 0.57376(11) 0.5452(5) 0.0221(5) Uani 1 1 d . . . . . H3A H 0.6260 0.6238 0.4845 0.027 Uiso 1 1 calc R . . . . C1 C 0.71705(10) 0.5000 0.8140(7) 0.0213(6) Uani 1 2 d S T P . . H1 H 0.7507 0.5000 0.9351 0.026 Uiso 1 2 calc RS T P . . C4 C 0.61844(10) 0.5000 0.4556(7) 0.0220(6) Uani 1 2 d S T P . . C5 C 0.56603(11) 0.5000 0.2605(7) 0.0221(6) Uani 1 2 d S T P . . O1S O 0.8486(9) 0.5000 0.524(6) 0.183(7) Uiso 0.5 2 d S T P A 1 O9S O 0.5669(6) 0.7705(10) 0.551(6) 0.196(6) Uiso 0.5 1 d . . . B 10 O2S O 0.8523(9) 0.5000 0.948(6) 0.184(7) Uiso 0.5 2 d S T P C 2 O8S O 0.5789(10) 0.7824(16) 0.196(9) 0.247(8) Uiso 0.5 1 d . . . D 13 O3S O 0.6319(19) 0.088(3) 0.416(13) 0.237(16) Uiso 0.25 1 d . . . E 4 O6S O 0.4090(17) 0.189(3) 0.147(15) 0.235(15) Uiso 0.25 1 d . . . F 6 O15S O 0.5030(15) 1.0000 0.722(9) 0.290(16) Uiso 0.5 2 d S T P G 15 O10S O 0.5604(11) 0.7649(17) 0.927(10) 0.159(8) Uiso 0.25 1 d . . . H 8 O7S O 0.6034(15) 0.863(2) 0.531(13) 0.202(12) Uiso 0.25 1 d . . . I 12 H2 H 0.7086(13) 0.7597(14) 0.801(10) 0.067(11) Uiso 1 1 d D . . . . O5S O 0.3936(15) 0.857(3) 0.778(13) 0.208(13) Uiso 0.25 1 d . . . J 5 H3 H 0.517(2) 0.430(3) 0.082(17) 0.038(16) Uiso 0.5 1 d . . . . . O4S O 0.3790(14) 0.910(2) 0.104(11) 0.210(12) Uiso 0.25 1 d . . . K 3 O13S O 0.556(3) 0.956(4) 0.08(2) 0.23(3) Uiso 0.125 1 d . . . L 16 O14S O 0.477(4) 0.907(7) 0.57(4) 0.31(5) Uiso 0.125 1 d . . . M 14 O11S O 0.5139(18) 0.768(3) 0.646(11) 0.143(13) Uiso 0.125 1 d . . . N 9 O12S O 0.5000 0.760(4) 1.0000 0.24(2) Uiso 0.25 2 d S T P O 7 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0294(9) 0.0249(8) 0.0352(8) -0.0001(6) -0.0106(6) -0.0024(5) O2 0.0350(9) 0.0192(8) 0.0409(9) -0.0002(6) -0.0114(6) 0.0002(6) O3 0.0279(9) 0.0359(10) 0.0436(10) 0.0001(6) -0.0117(7) -0.0063(6) C6 0.0252(9) 0.0209(10) 0.0221(9) -0.0005(6) -0.0020(7) 0.0003(7) C2 0.0242(10) 0.0214(11) 0.0191(8) -0.0003(6) -0.0007(7) -0.0012(7) C3 0.0249(10) 0.0217(10) 0.0195(8) 0.0001(7) -0.0007(7) 0.0020(7) C1 0.0195(12) 0.0240(13) 0.0198(12) 0.000 -0.0025(9) 0.000 C4 0.0212(13) 0.0263(14) 0.0183(12) 0.000 -0.0002(10) 0.000 C5 0.0220(13) 0.0233(13) 0.0209(12) 0.000 -0.0004(10) 0.000 _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C6 1.237(3) . ? O2 C6 1.295(2) . ? O2 H2 0.836(10) . ? O3 C5 1.265(2) . ? O3 H3 0.80(6) . ? C6 C2 1.490(3) . ? C2 C3 1.395(3) . ? C2 C1 1.394(2) . ? C3 H3A 0.9500 . ? C3 C4 1.394(2) . ? C1 C2 1.394(2) 6_565 ? C1 H1 0.9500 . ? C4 C3 1.394(2) 6_565 ? C4 C5 1.488(4) . ? C5 O3 1.265(2) 6_565 ? O15S O15S 1.60(6) 5_676 ? O13S O13S 1.44(14) 6_575 ? O14S O14S 1.3(2) 2_656 ? O11S O11S 1.24(8) 2_656 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C6 O2 H2 114(3) . . ? C5 O3 H3 120(4) . . ? O1 C6 O2 124.65(18) . . ? O1 C6 C2 120.01(17) . . ? O2 C6 C2 115.33(17) . . ? C3 C2 C6 120.56(17) . . ? C1 C2 C6 119.01(18) . . ? C1 C2 C3 120.39(18) . . ? C2 C3 H3A 120.3 . . ? C4 C3 C2 119.47(18) . . ? C4 C3 H3A 120.3 . . ? C2 C1 C2 119.7(2) 6_565 . ? C2 C1 H1 120.2 6_565 . ? C2 C1 H1 120.2 . . ? C3 C4 C3 120.6(2) . 6_565 ? C3 C4 C5 119.71(12) 6_565 . ? C3 C4 C5 119.70(12) . . ? O3 C5 O3 124.9(3) . 6_565 ? O3 C5 C4 117.57(13) 6_565 . ? O3 C5 C4 117.57(13) . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O2 H2 O1 0.836(10) 1.782(11) 2.618(2) 178(4) 7_667 O3 H3 O3 0.80(6) 1.83(6) 2.622(3) 175(6) 2_655 _shelx_res_file ; tma_7-36_dioxane-1,3-dimethoxybenzene__c2c_100k.res created by SHELXL-2014/7 TITL TMA_7-36_Dioxane-dimethoxybenzene_C2c_100K_TWIN5.res in C2/m REM Old TITL TMA_Diox_DMB_100K_C2-c in C2/m REM SHELXT solution in C2/m REM R1 0.177, Rweak 0.013, Alpha 0.062, Orientation as input REM Formula found by SHELXT: C9 O6 CELL 0.71073 25.869 16.4191 3.606 90 93.617 90 ZERR 4 0.0044 0.0028 0.0006 0 0.004 0 LATT 7 SYMM -X,+Y,-Z SFAC C H O UNIT 36 24 54 EQIV $1 1.5-X,1.5-Y,2-Z EQIV $2 1-X,+Y,-Z DFIX 0.83 0.01 O2 H2 L.S. 20 0 0 PLAN 20 SIZE 0.17 0.11 0.09 TEMP -173.15 HTAB O2 O1_$1 HTAB O3 O3_$2 BOND $H list 4 fmap 2 53 acta SHEL 999 0.8 OMIT 1 1 0 REM REM REM WGHT 0.123100 2.149900 BASF 0.07013 FVAR 0.74707 O1 3 0.759437 0.650179 1.031229 11.00000 0.02938 0.02494 = 0.03520 -0.00011 -0.01065 -0.00242 O2 3 0.694731 0.716773 0.719112 11.00000 0.03499 0.01916 = 0.04092 -0.00016 -0.01136 0.00021 O3 3 0.545547 0.431689 0.181425 11.00000 0.02789 0.03595 = 0.04365 0.00014 -0.01171 -0.00634 C6 1 0.718364 0.651272 0.836230 11.00000 0.02518 0.02093 = 0.02210 -0.00052 -0.00198 0.00032 C2 1 0.692217 0.573405 0.724750 11.00000 0.02423 0.02140 = 0.01910 -0.00033 -0.00065 -0.00123 C3 1 0.642847 0.573757 0.545218 11.00000 0.02489 0.02173 = 0.01953 0.00009 -0.00073 0.00204 AFIX 43 H3A 2 0.625990 0.623850 0.484521 11.00000 -1.20000 AFIX 0 C1 1 0.717051 0.500000 0.813975 10.50000 0.01946 0.02402 = 0.01984 0.00000 -0.00255 0.00000 AFIX 43 H1 2 0.750748 0.500001 0.935057 10.50000 -1.20000 AFIX 0 C4 1 0.618443 0.500000 0.455578 10.50000 0.02119 0.02629 = 0.01826 0.00000 -0.00018 0.00000 C5 1 0.566029 0.500000 0.260517 10.50000 0.02202 0.02325 = 0.02094 0.00000 -0.00043 0.00000 PART 1 O1S 3 0.848568 0.500000 0.524368 10.25000 0.18289 PART 0 PART 10 O9S 3 0.566912 0.770521 0.550656 10.50000 0.19566 PART 0 PART 2 O2S 3 0.852309 0.500000 0.948212 10.25000 0.18424 PART 0 PART 13 O8S 3 0.578916 0.782370 0.195642 10.50000 0.24688 PART 0 PART 4 O3S 3 0.631905 0.087813 0.416225 10.25000 0.23747 PART 0 PART 6 O6S 3 0.408952 0.189066 0.147165 10.25000 0.23510 PART 0 PART 15 O15S 3 0.502955 1.000000 0.721917 10.25000 0.29040 PART 0 PART 8 O10S 3 0.560397 0.764918 0.926681 10.25000 0.15899 PART 0 PART 12 O7S 3 0.603391 0.863331 0.531228 10.25000 0.20163 PART 0 H2 2 0.708595 0.759703 0.800726 11.00000 0.06678 PART 5 O5S 3 0.393552 0.857498 0.778398 10.25000 0.20837 PART 0 H3 2 0.517213 0.429778 0.081527 10.50000 0.03785 PART 3 O4S 3 0.378969 0.910163 0.103784 10.25000 0.20958 PART 0 PART 16 O13S 3 0.556368 0.956061 0.081979 10.12500 0.22516 PART 0 PART 14 O14S 3 0.477147 0.907171 0.574020 10.12500 0.31082 PART 0 PART 9 O11S 3 0.513934 0.767557 0.645789 10.12500 0.14337 PART 0 PART 7 O12S 3 0.500000 0.760277 1.000000 10.12500 0.23780 HKLF 5 REM TMA_7-36_Dioxane-dimethoxybenzene_C2c_100K_TWIN5.res in C2/m REM R1 = 0.0688 for 1533 Fo > 4sig(Fo) and 0.0727 for all 1664 data REM 137 parameters refined using 1 restraints END WGHT 0.1229 2.1521 REM Highest difference peak 0.317, deepest hole -0.415, 1-sigma level 0.072 Q1 1 0.8596 0.5333 0.2636 11.00000 0.05 0.32 Q2 1 0.6018 0.5000 0.3588 10.50000 0.05 0.30 Q3 1 0.5823 0.7962 0.6641 11.00000 0.05 0.30 Q4 1 0.3808 0.9118 -0.1086 11.00000 0.05 0.29 Q5 1 0.6143 0.8796 0.6705 11.00000 0.05 0.28 Q6 1 0.5000 1.0000 0.5000 10.25000 0.05 0.28 Q7 1 0.7037 0.6101 0.7817 11.00000 0.05 0.27 Q8 1 0.5790 0.7801 0.1036 11.00000 0.05 0.26 Q9 1 0.5625 0.9683 0.3894 11.00000 0.05 0.26 Q10 1 0.4009 0.1605 -0.0153 11.00000 0.05 0.25 Q11 1 0.8596 0.5255 0.8657 11.00000 0.05 0.24 Q12 1 0.5070 1.0000 0.9038 10.50000 0.05 0.22 Q13 1 0.4193 0.9147 0.6728 11.00000 0.05 0.20 Q14 1 0.4752 0.7579 0.7326 11.00000 0.05 0.20 Q15 1 0.6804 0.5760 0.6631 11.00000 0.05 0.18 Q16 1 0.4814 0.8422 0.6766 11.00000 0.05 0.17 Q17 1 0.7018 0.5441 0.7705 11.00000 0.05 0.16 Q18 1 0.7264 0.7984 0.8985 11.00000 0.05 0.16 Q19 1 0.6585 0.7172 0.5266 11.00000 0.05 0.14 Q20 1 0.7426 0.5761 0.8885 11.00000 0.05 0.14 ; _shelx_res_checksum 9493 _olex2_submission_special_instructions 'No special instructions were received' loop_ _twin_individual_id _twin_individual_mass_fraction_refined 1 0.930(4) 2 0.070(4) ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_tma_6-18 _database_code_depnum_ccdc_archive 'CCDC 1915310' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2019-02-17 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2018/3 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6, C3 H8 O' _chemical_formula_sum 'C12 H14 O7' _chemical_formula_weight 270.23 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system triclinic _space_group_IT_number 2 _space_group_name_H-M_alt 'P -1' _space_group_name_Hall '-P 1' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, -y, -z' _cell_length_a 9.1671(17) _cell_length_b 9.4589(18) _cell_length_c 9.6179(17) _cell_angle_alpha 93.220(5) _cell_angle_beta 116.280(5) _cell_angle_gamma 118.728(5) _cell_volume 616.2(2) _cell_formula_units_Z 2 _cell_measurement_reflns_used 2579 _cell_measurement_temperature 100.0 _cell_measurement_theta_max 31.078 _cell_measurement_theta_min 2.514 _shelx_estimated_absorpt_T_max 0.990 _shelx_estimated_absorpt_T_min 0.952 _exptl_absorpt_coefficient_mu 0.121 _exptl_absorpt_correction_T_max 0.7462 _exptl_absorpt_correction_T_min 0.4729 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2016/2 (Bruker,2016/2) was used for absorption correction. wR2(int) was 0.0821 before and 0.0498 after correction. The Ratio of minimum to maximum transmission is 0.6337. The \l/2 correction factor is Not present.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.457 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 284 _exptl_crystal_size_max 0.408 _exptl_crystal_size_mid 0.315 _exptl_crystal_size_min 0.079 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0833 _diffrn_reflns_av_unetI/netI 0.0798 _diffrn_reflns_Laue_measured_fraction_full 0.998 _diffrn_reflns_Laue_measured_fraction_max 0.990 _diffrn_reflns_limit_h_max 12 _diffrn_reflns_limit_h_min -13 _diffrn_reflns_limit_k_max 13 _diffrn_reflns_limit_k_min -13 _diffrn_reflns_limit_l_max 13 _diffrn_reflns_limit_l_min -8 _diffrn_reflns_number 8579 _diffrn_reflns_point_group_measured_fraction_full 0.998 _diffrn_reflns_point_group_measured_fraction_max 0.990 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 31.139 _diffrn_reflns_theta_min 2.513 _diffrn_ambient_temperature 100.0 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.998 _diffrn_measured_fraction_theta_max 0.990 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 2510 _reflns_number_total 3929 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT V8.38A (?, 2016)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT V8.38A (?, 2016)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'ShelXL (Sheldrick, 2015)' _computing_structure_solution 'SHELXT 2018/2 (Sheldrick, 2018)' _refine_diff_density_max 0.302 _refine_diff_density_min -0.330 _refine_diff_density_rms 0.066 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 0.912 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 189 _refine_ls_number_reflns 3929 _refine_ls_number_restraints 3 _refine_ls_R_factor_all 0.0759 _refine_ls_R_factor_gt 0.0486 _refine_ls_restrained_S_all 0.914 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0559P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1107 _refine_ls_wR_factor_ref 0.1203 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups, All C(H,H) groups At 1.5 times of: All C(H,H,H) groups 2. Restrained distances O3-H3 = O1-H1 = O6-H6 0.83 with sigma of 0.01 3.a Secondary CH2 refined with riding coordinates: C11(H11A,H11B), C12(H12A,H12B) 3.b Aromatic/amide H refined with riding coordinates: C2(H2), C4(H4), C6(H6A) 3.c Idealised Me refined as rotating group: C10(H10A,H10B,H10C) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.24490(14) 0.24062(13) 0.71886(12) 0.0244(2) Uani 1 1 d D . . . . H1 H 0.301(2) 0.262(2) 0.8234(12) 0.049(6) Uiso 1 1 d D . . . . O2 O 0.54398(13) 0.34081(13) 0.76165(11) 0.0255(2) Uani 1 1 d . . . . . O3 O 0.59758(14) 0.35982(13) 0.26695(12) 0.0261(2) Uani 1 1 d D . . . . H3 H 0.655(3) 0.374(3) 0.214(2) 0.073(8) Uiso 1 1 d D . . . . O4 O 0.33042(14) 0.27029(13) 0.01930(11) 0.0253(2) Uani 1 1 d . . . . . O5 O -0.32876(14) 0.04364(13) 0.18307(11) 0.0247(2) Uani 1 1 d . . . . . O6 O -0.29773(14) 0.06839(13) -0.03488(11) 0.0235(2) Uani 1 1 d D . . . . H6 H -0.4167(15) 0.034(2) -0.080(2) 0.057(6) Uiso 1 1 d D . . . . C1 C 0.36937(19) 0.28164(17) 0.66983(16) 0.0196(3) Uani 1 1 d . . . . . C2 C 0.38515(18) 0.28727(16) 0.41815(15) 0.0189(3) Uani 1 1 d . . . . . H2 H 0.521698 0.333085 0.484952 0.023 Uiso 1 1 calc R . . . . C3 C 0.27292(18) 0.24904(16) 0.48894(15) 0.0182(3) Uani 1 1 d . . . . . C4 C 0.07292(18) 0.18181(16) 0.39097(16) 0.0190(3) Uani 1 1 d . . . . . H4 H -0.003870 0.154872 0.438988 0.023 Uiso 1 1 calc R . . . . C5 C -0.01457(18) 0.15405(17) 0.22225(16) 0.0190(3) Uani 1 1 d . . . . . C6 C 0.09619(18) 0.19124(16) 0.15145(15) 0.0190(3) Uani 1 1 d . . . . . H6A H 0.035756 0.171220 0.036240 0.023 Uiso 1 1 calc R . . . . C7 C 0.29670(18) 0.25817(16) 0.24927(15) 0.0185(3) Uani 1 1 d . . . . . C8 C 0.40951(19) 0.29612(17) 0.16745(15) 0.0193(3) Uani 1 1 d . . . . . C9 C -0.22916(19) 0.08376(17) 0.12112(16) 0.0199(3) Uani 1 1 d . . . . . O7 O -0.22770(14) 0.41116(14) 0.10713(12) 0.0260(2) Uani 1 1 d . . . . . H7 H -0.304(3) 0.385(2) 0.005(2) 0.041(5) Uiso 1 1 d . . . . . C10 C 0.2554(2) 0.81948(19) 0.42380(19) 0.0317(4) Uani 1 1 d . . . . . H10A H 0.329965 0.831078 0.372124 0.048 Uiso 1 1 calc GR . . . . H10B H 0.340794 0.852270 0.543348 0.048 Uiso 1 1 calc GR . . . . H10C H 0.208782 0.894445 0.400714 0.048 Uiso 1 1 calc GR . . . . C11 C 0.0788(2) 0.63314(18) 0.35389(17) 0.0243(3) Uani 1 1 d . . . . . H11A H 0.125633 0.557767 0.382306 0.029 Uiso 1 1 calc R . . . . H11B H 0.000848 0.621716 0.403328 0.029 Uiso 1 1 calc R . . . . C12 C -0.04883(19) 0.57898(18) 0.16944(17) 0.0248(3) Uani 1 1 d . . . . . H12A H -0.081703 0.662935 0.140333 0.030 Uiso 1 1 calc R . . . . H12B H 0.023182 0.575548 0.118634 0.030 Uiso 1 1 calc R . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0247(5) 0.0378(6) 0.0152(4) 0.0119(4) 0.0139(4) 0.0174(4) O2 0.0201(4) 0.0344(6) 0.0160(4) 0.0081(4) 0.0095(4) 0.0118(4) O3 0.0193(4) 0.0376(6) 0.0176(5) 0.0088(4) 0.0114(4) 0.0122(4) O4 0.0254(5) 0.0379(6) 0.0157(4) 0.0109(4) 0.0133(4) 0.0176(4) O5 0.0218(4) 0.0369(6) 0.0190(5) 0.0122(4) 0.0127(4) 0.0170(4) O6 0.0203(4) 0.0368(6) 0.0152(4) 0.0094(4) 0.0100(4) 0.0167(4) C1 0.0215(6) 0.0210(6) 0.0170(6) 0.0068(5) 0.0126(5) 0.0103(5) C2 0.0189(6) 0.0207(6) 0.0159(6) 0.0066(5) 0.0097(5) 0.0100(5) C3 0.0196(6) 0.0193(6) 0.0152(6) 0.0058(5) 0.0101(5) 0.0100(5) C4 0.0200(6) 0.0224(6) 0.0166(6) 0.0068(5) 0.0115(5) 0.0117(5) C5 0.0194(6) 0.0218(6) 0.0169(6) 0.0068(5) 0.0104(5) 0.0118(5) C6 0.0213(6) 0.0215(6) 0.0146(5) 0.0070(5) 0.0103(5) 0.0118(5) C7 0.0208(6) 0.0200(6) 0.0157(6) 0.0068(5) 0.0109(5) 0.0111(5) C8 0.0202(6) 0.0217(6) 0.0161(6) 0.0061(5) 0.0106(5) 0.0111(5) C9 0.0220(6) 0.0242(7) 0.0164(6) 0.0082(5) 0.0118(5) 0.0135(5) O7 0.0207(5) 0.0344(6) 0.0168(5) 0.0078(4) 0.0105(4) 0.0113(4) C10 0.0289(7) 0.0296(8) 0.0299(8) 0.0075(6) 0.0156(6) 0.0125(6) C11 0.0248(6) 0.0278(7) 0.0210(6) 0.0094(6) 0.0128(5) 0.0148(6) C12 0.0229(6) 0.0309(7) 0.0218(6) 0.0107(6) 0.0144(5) 0.0135(6) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C1 1.3214(16) . ? O2 C1 1.2194(16) . ? O3 C8 1.3141(16) . ? O4 C8 1.2212(15) . ? O5 C9 1.2274(15) . ? O6 C9 1.3115(16) . ? C1 C3 1.4897(18) . ? C2 C3 1.3940(18) . ? C2 C7 1.3930(17) . ? C3 C4 1.3913(18) . ? C4 C5 1.3937(18) . ? C5 C6 1.3836(18) . ? C5 C9 1.4945(18) . ? C6 C7 1.3956(18) . ? C7 C8 1.4876(18) . ? O7 C12 1.4451(17) . ? C10 C11 1.530(2) . ? C11 C12 1.5041(19) . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag O1 C1 C3 112.40(11) . . ? O2 C1 O1 124.18(12) . . ? O2 C1 C3 123.42(12) . . ? C7 C2 C3 119.87(12) . . ? C2 C3 C1 119.39(11) . . ? C4 C3 C1 120.59(12) . . ? C4 C3 C2 120.02(12) . . ? C3 C4 C5 119.89(12) . . ? C4 C5 C9 118.45(12) . . ? C6 C5 C4 120.26(12) . . ? C6 C5 C9 121.29(12) . . ? C5 C6 C7 120.00(12) . . ? C2 C7 C6 119.97(12) . . ? C2 C7 C8 122.04(12) . . ? C6 C7 C8 117.99(11) . . ? O3 C8 C7 114.77(11) . . ? O4 C8 O3 123.78(12) . . ? O4 C8 C7 121.46(12) . . ? O5 C9 O6 124.47(12) . . ? O5 C9 C5 121.03(12) . . ? O6 C9 C5 114.50(11) . . ? C12 C11 C10 109.95(13) . . ? O7 C12 C11 109.47(12) . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A _geom_hbond_publ_flag O1 H1 O4 0.858(9) 1.773(11) 2.5951(14) 159.8(18) 1_556 yes O3 H3 O7 0.857(10) 1.729(10) 2.5847(14) 178(2) 1_655 yes O6 H6 O5 0.841(9) 1.786(9) 2.6266(15) 178(2) 2_455 yes O7 H7 O2 0.85(2) 2.01(2) 2.8493(15) 173.0(17) 1_454 yes _shelx_res_file ; TITL TMA_6-18.res in P-1 tma_6-18.res created by SHELXL-2018/3 at 11:11:05 on 17-Feb-2019 REM Old TITL test in P-1 REM SHELXT solution in P-1: R1 0.120, Rweak 0.003, Alpha 0.019 REM 0.000 for 0 systematic absences, Orientation as input REM Formula found by SHELXT: C12 O7 CELL 0.71073 9.1671 9.4589 9.6179 93.22 116.28 118.728 ZERR 2 0.0017 0.0018 0.0017 0.005 0.005 0.005 LATT 1 SFAC C H O UNIT 24 28 14 EQIV $1 -1-X,-Y,-Z EQIV $2 1+X,+Y,+Z EQIV $3 +X,+Y,1+Z EQIV $4 -1+X,+Y,-1+Z DFIX 0.83 0.01 O3 H3 O1 H1 O6 H6 L.S. 40 PLAN 20 SIZE 0.408 0.315 0.079 TEMP -173.15 HTAB O6 O5_$1 HTAB O3 O7_$2 HTAB O1 O4_$3 HTAB O7 O2_$4 list 4 fmap 2 53 acta REM REM REM WGHT 0.055900 FVAR 0.62355 O1 3 0.244904 0.240618 0.718860 11.00000 0.02466 0.03785 = 0.01523 0.01193 0.01390 0.01737 H1 2 0.301182 0.261892 0.823434 11.00000 0.04861 O2 3 0.543981 0.340810 0.761646 11.00000 0.02008 0.03439 = 0.01601 0.00811 0.00949 0.01181 O3 3 0.597579 0.359818 0.266952 11.00000 0.01926 0.03759 = 0.01757 0.00878 0.01142 0.01218 H3 2 0.654594 0.373849 0.213512 11.00000 0.07279 O4 3 0.330418 0.270294 0.019303 11.00000 0.02538 0.03786 = 0.01567 0.01090 0.01326 0.01756 O5 3 -0.328756 0.043640 0.183070 11.00000 0.02180 0.03689 = 0.01903 0.01221 0.01274 0.01703 O6 3 -0.297730 0.068388 -0.034877 11.00000 0.02031 0.03683 = 0.01523 0.00935 0.01005 0.01672 H6 2 -0.416704 0.034183 -0.080294 11.00000 0.05708 C1 1 0.369368 0.281639 0.669828 11.00000 0.02150 0.02101 = 0.01704 0.00682 0.01258 0.01035 C2 1 0.385155 0.287273 0.418152 11.00000 0.01893 0.02074 = 0.01588 0.00657 0.00973 0.01002 AFIX 43 H2 2 0.521698 0.333085 0.484952 11.00000 -1.20000 AFIX 0 C3 1 0.272920 0.249044 0.488939 11.00000 0.01961 0.01932 = 0.01515 0.00576 0.01009 0.00998 C4 1 0.072923 0.181811 0.390968 11.00000 0.02002 0.02242 = 0.01658 0.00683 0.01152 0.01172 AFIX 43 H4 2 -0.003870 0.154872 0.438988 11.00000 -1.20000 AFIX 0 C5 1 -0.014569 0.154051 0.222253 11.00000 0.01942 0.02180 = 0.01690 0.00683 0.01042 0.01181 C6 1 0.096194 0.191242 0.151445 11.00000 0.02130 0.02153 = 0.01462 0.00701 0.01026 0.01180 AFIX 43 H6A 2 0.035756 0.171220 0.036240 11.00000 -1.20000 AFIX 0 C7 1 0.296701 0.258167 0.249268 11.00000 0.02076 0.02004 = 0.01565 0.00682 0.01091 0.01107 C8 1 0.409510 0.296124 0.167449 11.00000 0.02020 0.02167 = 0.01605 0.00608 0.01058 0.01106 C9 1 -0.229161 0.083765 0.121125 11.00000 0.02196 0.02416 = 0.01644 0.00824 0.01176 0.01346 O7 3 -0.227698 0.411160 0.107126 11.00000 0.02067 0.03443 = 0.01679 0.00782 0.01053 0.01132 H7 2 -0.304309 0.385282 0.004733 11.00000 0.04112 C10 1 0.255450 0.819475 0.423801 11.00000 0.02888 0.02956 = 0.02990 0.00750 0.01564 0.01254 AFIX 137 H10A 2 0.329965 0.831078 0.372124 11.00000 -1.50000 H10B 2 0.340794 0.852270 0.543348 11.00000 -1.50000 H10C 2 0.208782 0.894445 0.400714 11.00000 -1.50000 AFIX 0 C11 1 0.078758 0.633144 0.353894 11.00000 0.02481 0.02779 = 0.02104 0.00941 0.01280 0.01475 AFIX 23 H11A 2 0.125633 0.557767 0.382306 11.00000 -1.20000 H11B 2 0.000848 0.621716 0.403328 11.00000 -1.20000 AFIX 0 C12 1 -0.048829 0.578983 0.169441 11.00000 0.02286 0.03093 = 0.02179 0.01074 0.01445 0.01353 AFIX 23 H12A 2 -0.081703 0.662935 0.140333 11.00000 -1.20000 H12B 2 0.023182 0.575548 0.118634 11.00000 -1.20000 AFIX 0 HKLF 4 REM TMA_6-18.res in P-1 REM wR2 = 0.1203, GooF = S = 0.912, Restrained GooF = 0.914 for all data REM R1 = 0.0486 for 2510 Fo > 4sig(Fo) and 0.0759 for all 3929 data REM 189 parameters refined using 3 restraints END WGHT 0.0559 0.0000 REM Highest difference peak 0.302, deepest hole -0.330, 1-sigma level 0.066 Q1 1 0.3559 0.2804 0.3410 11.00000 0.05 0.30 Q2 1 0.2085 0.2510 0.1965 11.00000 0.05 0.30 Q3 1 0.0241 0.1752 0.2986 11.00000 0.05 0.30 Q4 1 0.3029 0.2640 0.5570 11.00000 0.05 0.28 Q5 1 -0.3753 -0.0768 -0.1013 11.00000 0.05 0.25 Q6 1 0.1640 0.1753 0.4424 11.00000 0.05 0.25 Q7 1 0.2185 0.2026 -0.0228 11.00000 0.05 0.25 Q8 1 0.3012 0.3579 0.0005 11.00000 0.05 0.24 Q9 1 -0.2169 0.1200 -0.1194 11.00000 0.05 0.24 Q10 1 -0.2385 0.1971 0.0197 11.00000 0.05 0.24 Q11 1 0.4788 0.4592 0.2195 11.00000 0.05 0.23 Q12 1 0.2967 0.1454 -0.0159 11.00000 0.05 0.23 Q13 1 0.3208 0.1366 0.0800 11.00000 0.05 0.23 Q14 1 -0.2280 0.5242 0.1060 11.00000 0.05 0.22 Q15 1 0.1409 0.7363 0.3831 11.00000 0.05 0.22 Q16 1 0.3441 0.3658 0.1133 11.00000 0.05 0.22 Q17 1 0.4788 0.4051 0.7181 11.00000 0.05 0.22 Q18 1 0.5238 0.2345 0.1992 11.00000 0.05 0.22 Q19 1 0.1875 0.2629 0.4343 11.00000 0.05 0.21 Q20 1 0.1594 0.2982 0.6613 11.00000 0.05 0.21 ; _shelx_res_checksum 5598 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_3-36_EtOH_Ph2O_publ _database_code_depnum_ccdc_archive 'CCDC 1915309' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2018-05-21 _audit_creation_method ; Olex2 1.2 (compiled 2018.04.26 svn.r3504 for OlexSys, GUI svn.r5492) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety '3(C9 H6 O6), 2(C12 H10 O)' _chemical_formula_sum 'C51 H38 O20' _chemical_formula_weight 970.81 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0028 0.0015 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0101 0.0057 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system triclinic _space_group_IT_number 2 _space_group_name_H-M_alt 'P -1' _space_group_name_Hall '-P 1' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, -y, -z' _cell_length_a 10.50240(6) _cell_length_b 15.88590(7) _cell_length_c 16.60930(7) _cell_angle_alpha 113.7260(4) _cell_angle_beta 98.4480(4) _cell_angle_gamma 106.8020(4) _cell_volume 2316.46(2) _cell_formula_units_Z 2 _cell_measurement_reflns_used 21452 _cell_measurement_temperature 200 _cell_measurement_theta_max 35.6992161017 _cell_measurement_theta_min 1.35437565248 _shelx_estimated_absorpt_T_max 0.998 _shelx_estimated_absorpt_T_min 0.992 _exptl_absorpt_coefficient_mu 0.100 _exptl_absorpt_correction_T_max 1.0 _exptl_absorpt_correction_T_min 0.995896160689 _exptl_absorpt_correction_type empirical _exptl_absorpt_process_details ; CCP4 7.0.052: AIMLESS, version 0.6.2 : 15/01/18 Scaling & analysis of unmerged intensities, absorption correction using spherical harmonics ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.392 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 1008 _exptl_crystal_size_max 0.078 _exptl_crystal_size_mid 0.028 _exptl_crystal_size_min 0.024 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0281 _diffrn_reflns_av_unetI/netI 0.0317 _diffrn_reflns_Laue_measured_fraction_full 0.992 _diffrn_reflns_Laue_measured_fraction_max 0.988 _diffrn_reflns_limit_h_max 14 _diffrn_reflns_limit_h_min -14 _diffrn_reflns_limit_k_max 21 _diffrn_reflns_limit_k_min -21 _diffrn_reflns_limit_l_max 22 _diffrn_reflns_limit_l_min -22 _diffrn_reflns_number 36998 _diffrn_reflns_point_group_measured_fraction_full 0.992 _diffrn_reflns_point_group_measured_fraction_max 0.988 _diffrn_reflns_theta_full 24.415 _diffrn_reflns_theta_max 28.152 _diffrn_reflns_theta_min 1.361 _diffrn_ambient_temperature 200 _diffrn_detector 'Photon counting pixel array' _diffrn_detector_area_resol_mean PILATUS_2M_S_N_24_0107_Diamond _diffrn_detector_type PILATUS_2M_S_N_24_0107_Diamond _diffrn_measured_fraction_theta_full 0.992 _diffrn_measured_fraction_theta_max 0.988 _diffrn_measurement_device 'Fixed \c 3-circle diffractometer' _diffrn_measurement_device_type 'Fluid Film Devices' _diffrn_measurement_method 'shutterless scans' _diffrn_radiation_collimation '0.3 x 1.5 Double Pinhole' _diffrn_radiation_monochromator 'Silicon 111' _diffrn_radiation_source 'Diamond Light Source Beamline I19-1' _diffrn_radiation_probe x-ray _diffrn_radiation_type ? _diffrn_radiation_wavelength 0.6889 _diffrn_source Synchrotron _diffrn_source_type 'Undulator, I19, DLS, RAL' _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 8999 _reflns_number_total 12320 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'DIALS 2theta refinement, DIALS 1.9.3-gb491019a-release' _computing_data_collection 'Diamond I19 GDA, (Diamond, RAL, Didcot, UK)' _computing_data_reduction ; aimless (Evans, P. R. and Murshudov, G. N., 2013) ccp4 (Winn, M. D. et al., 2011) DIALS 1.9.3-gb491019a-release (Winter, G. et al., 2018) pointless (Evans, P., 2006) XIA2 0.5.546-gdf2e0b53-dials-1.9 (Winter, G., 2010) ; _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2014)' _computing_structure_solution 'XT (Sheldrick, 2014)' _refine_diff_density_max 0.306 _refine_diff_density_min -0.380 _refine_diff_density_rms 0.110 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.100 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 700 _refine_ls_number_reflns 12320 _refine_ls_number_restraints 196 _refine_ls_R_factor_all 0.0559 _refine_ls_R_factor_gt 0.0429 _refine_ls_restrained_S_all 1.113 _refine_ls_shift/su_max 0.001 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0900P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1345 _refine_ls_wR_factor_ref 0.1429 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups 2. Restrained distances O17-H17 = O14-H14 = O1-H1 = O16-H16 = O8-H8 = O9-H9 = O3-H3 = O12-H12 = O6-H6 0.82 with sigma of 0.02 C16-H8 1.79 with sigma of 0.04 3. Rigid body (RIGU) restrains O20, C40, C46, C41, C45, C47, C51, C42, C44, C48, C50, C43, C49 with sigma for 1-2 distances of 0.004 and sigma for 1-3 distances of 0.004 O19, C28, C34, C29, C33, C35, C39, C30, C32, C36, C38, C31, C37 with sigma for 1-2 distances of 0.004 and sigma for 1-3 distances of 0.004 4.a Aromatic/amide H refined with riding coordinates: C29(H29), C30(H30), C31(H31), C32(H32), C33(H33), C35(H35), C36(H36), C37(H37), C38(H38), C39(H39), C45(H45), C44(H44), C43(H43), C42(H42), C41(H41), C47(H47), C48(H48), C49(H49), C50(H50), C51(H51) 4.b Fitted hexagon refined as free rotating group: C40(C45,C44,C43,C42,C41) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.25801(8) 0.57341(5) 0.54135(5) 0.04235(18) Uani 1 1 d D . . . . O2 O 0.10812(8) 0.44126(6) 0.54189(5) 0.0470(2) Uani 1 1 d . . . . . O3 O 0.10033(8) 0.43518(5) 0.83190(5) 0.04244(18) Uani 1 1 d D . . . . O4 O 0.25003(8) 0.56189(5) 0.96519(5) 0.04090(18) Uani 1 1 d . . . . . O5 O 0.53110(8) 0.87065(5) 0.96739(5) 0.04156(18) Uani 1 1 d . . . . . O6 O 0.54199(8) 0.87047(5) 0.83362(5) 0.03993(17) Uani 1 1 d D . . . . C1 C 0.25567(9) 0.57752(7) 0.68467(6) 0.02832(18) Uani 1 1 d . . . . . C2 C 0.20907(9) 0.52540(7) 0.73197(6) 0.02850(18) Uani 1 1 d . . . . . C3 C 0.25462(9) 0.57341(6) 0.82783(6) 0.02687(17) Uani 1 1 d . . . . . C4 C 0.34808(9) 0.67258(6) 0.87663(6) 0.02744(18) Uani 1 1 d . . . . . C5 C 0.39438(9) 0.72371(6) 0.82848(6) 0.02682(17) Uani 1 1 d . . . . . C6 C 0.34838(9) 0.67695(7) 0.73288(6) 0.02839(18) Uani 1 1 d . . . . . C7 C 0.20324(10) 0.52678(7) 0.58217(6) 0.03074(19) Uani 1 1 d . . . . . C8 C 0.20104(9) 0.52140(6) 0.88053(6) 0.02857(18) Uani 1 1 d . . . . . C9 C 0.49595(9) 0.82943(6) 0.88263(6) 0.02862(18) Uani 1 1 d . . . . . O7 O 0.62380(8) 0.60519(5) 0.58729(5) 0.04253(18) Uani 1 1 d . . . . . O8 O 0.47613(8) 0.47564(5) 0.59321(5) 0.04299(19) Uani 1 1 d D . . . . O9 O 0.48372(8) 0.47075(5) 0.88187(5) 0.04130(18) Uani 1 1 d D . . . . O10 O 0.61357(8) 0.60638(5) 1.01624(4) 0.04148(18) Uani 1 1 d . . . . . O11 O 0.89943(8) 0.91133(5) 1.01300(5) 0.04050(18) Uani 1 1 d . . . . . O12 O 0.91164(8) 0.90681(5) 0.87789(5) 0.03699(16) Uani 1 1 d D . . . . C10 C 0.62547(9) 0.61354(6) 0.73299(6) 0.02575(17) Uani 1 1 d . . . . . C11 C 0.57933(9) 0.56276(6) 0.78152(6) 0.02654(17) Uani 1 1 d . . . . . C12 C 0.62454(9) 0.61288(6) 0.87737(6) 0.02586(17) Uani 1 1 d . . . . . C13 C 0.71615(9) 0.71260(6) 0.92497(6) 0.02592(17) Uani 1 1 d . . . . . C14 C 0.76342(9) 0.76194(6) 0.87585(6) 0.02492(17) Uani 1 1 d . . . . . C15 C 0.71815(9) 0.71299(6) 0.77980(6) 0.02637(17) Uani 1 1 d . . . . . C16 C 0.57421(9) 0.56301(6) 0.63053(6) 0.02870(18) Uani 1 1 d D . . . . C17 C 0.57290(9) 0.56191(6) 0.93128(6) 0.02850(18) Uani 1 1 d . . . . . C18 C 0.86452(9) 0.86752(6) 0.92867(6) 0.02687(17) Uani 1 1 d . . . . . O13 O 0.00803(8) 0.35640(5) -0.06402(5) 0.04282(18) Uani 1 1 d . . . . . O14 O 0.15207(8) 0.48760(5) 0.06888(5) 0.04148(18) Uani 1 1 d D . . . . O15 O 0.15080(8) 0.48565(5) 0.36168(5) 0.04171(18) Uani 1 1 d . . . . . O16 O 0.01252(9) 0.34936(6) 0.36295(5) 0.04576(19) Uani 1 1 d D . . . . O17 O -0.28777(8) 0.05573(5) 0.07374(5) 0.04145(18) Uani 1 1 d D . . . . O18 O -0.26623(8) 0.04966(5) -0.06065(5) 0.04480(19) Uani 1 1 d . . . . . C19 C 0.00457(9) 0.34806(6) 0.07480(6) 0.02694(17) Uani 1 1 d . . . . . C20 C -0.09069(9) 0.24953(6) 0.02752(6) 0.02841(18) Uani 1 1 d . . . . . C21 C -0.13669(9) 0.19972(6) 0.07653(6) 0.02754(18) Uani 1 1 d . . . . . C22 C -0.08882(9) 0.24749(6) 0.17221(6) 0.02828(18) Uani 1 1 d . . . . . C23 C 0.00654(9) 0.34641(6) 0.21927(6) 0.02734(17) Uani 1 1 d . . . . . C24 C 0.05309(9) 0.39681(6) 0.17050(6) 0.02749(18) Uani 1 1 d . . . . . C25 C 0.05554(9) 0.39872(6) 0.02063(6) 0.02874(18) Uani 1 1 d . . . . . C26 C -0.23778(10) 0.09394(6) 0.02355(6) 0.03033(19) Uani 1 1 d . . . . . C27 C 0.06058(10) 0.39771(7) 0.32142(6) 0.02985(18) Uani 1 1 d . . . . . O19 O 0.35697(17) 0.90722(9) 0.67133(8) 0.1064(5) Uani 1 1 d . U . . . C28 C 0.29553(16) 0.87566(10) 0.57951(9) 0.0616(3) Uani 1 1 d . U . . . C29 C 0.30960(17) 0.93773(10) 0.53983(9) 0.0629(4) Uani 1 1 d . U . . . H29 H 0.3657 1.0068 0.5755 0.075 Uiso 1 1 calc R . . . . C30 C 0.24087(17) 0.89807(12) 0.44737(10) 0.0694(4) Uani 1 1 d . U . . . H30 H 0.2483 0.9404 0.4196 0.083 Uiso 1 1 calc R . . . . C31 C 0.16127(16) 0.79720(13) 0.39500(11) 0.0743(4) Uani 1 1 d . U . . . H31 H 0.1142 0.7702 0.3314 0.089 Uiso 1 1 calc R . . . . C32 C 0.15093(15) 0.73697(11) 0.43539(12) 0.0732(4) Uani 1 1 d . U . . . H32 H 0.0982 0.6674 0.3992 0.088 Uiso 1 1 calc R . . . . C33 C 0.21543(15) 0.77528(10) 0.52742(11) 0.0681(4) Uani 1 1 d . U . . . H33 H 0.2050 0.7329 0.5552 0.082 Uiso 1 1 calc R . . . . C34 C 0.44349(19) 1.00698(11) 0.72701(9) 0.0728(4) Uani 1 1 d . U . . . C35 C 0.5784(2) 1.04051(13) 0.72622(11) 0.0792(4) Uani 1 1 d . U . . . H35 H 0.6128 0.9962 0.6866 0.095 Uiso 1 1 calc R . . . . C36 C 0.66357(19) 1.13793(13) 0.78262(11) 0.0807(4) Uani 1 1 d . U . . . H36 H 0.7571 1.1617 0.7818 0.097 Uiso 1 1 calc R . . . . C37 C 0.6147(2) 1.20129(13) 0.84024(10) 0.0805(5) Uani 1 1 d . U . . . H37 H 0.6746 1.2690 0.8795 0.097 Uiso 1 1 calc R . . . . C38 C 0.4792(2) 1.16792(15) 0.84207(11) 0.0848(5) Uani 1 1 d . U . . . H38 H 0.4463 1.2126 0.8825 0.102 Uiso 1 1 calc R . . . . C39 C 0.39026(19) 1.06868(15) 0.78473(11) 0.0808(5) Uani 1 1 d . U . . . H39 H 0.2966 1.0444 0.7853 0.097 Uiso 1 1 calc R . . . . O20 O 0.75604(13) 0.74226(8) 0.28618(8) 0.0871(4) Uani 1 1 d . U . . . C40 C 0.70607(10) 0.75272(7) 0.35964(6) 0.0642(4) Uani 1 1 d . U . . . C45 C 0.58124(10) 0.76650(8) 0.35952(7) 0.0811(4) Uani 1 1 d G U . . . H45 H 0.5316 0.7696 0.3088 0.097 Uiso 1 1 calc R . . . . C44 C 0.52912(10) 0.77573(9) 0.43355(9) 0.0927(6) Uani 1 1 d G U . . . H44 H 0.4438 0.7852 0.4335 0.111 Uiso 1 1 calc R . . . . C43 C 0.60182(13) 0.77119(8) 0.50770(7) 0.0859(5) Uani 1 1 d G U . . . H43 H 0.5662 0.7775 0.5583 0.103 Uiso 1 1 calc R . . . . C42 C 0.72665(11) 0.75741(7) 0.50782(6) 0.0805(5) Uani 1 1 d G U . . . H42 H 0.7763 0.7543 0.5585 0.097 Uiso 1 1 calc R . . . . C41 C 0.77877(8) 0.74817(7) 0.43379(8) 0.0698(4) Uani 1 1 d G U . . . H41 H 0.8641 0.7388 0.4339 0.084 Uiso 1 1 calc R . . . . C46 C 0.84611(14) 0.82709(10) 0.28982(9) 0.0574(3) Uani 1 1 d . U . . . C47 C 0.89302(14) 0.92053(9) 0.36457(8) 0.0577(3) Uani 1 1 d . U . . . H47 H 0.8637 0.9296 0.4179 0.069 Uiso 1 1 calc R . . . . C48 C 0.98282(18) 1.00046(11) 0.36088(10) 0.0724(4) Uani 1 1 d . U . . . H48 H 1.0145 1.0652 0.4117 0.087 Uiso 1 1 calc R . . . . C49 C 1.02746(19) 0.98765(15) 0.28409(12) 0.0814(5) Uani 1 1 d . U . . . H49 H 1.0908 1.0430 0.2825 0.098 Uiso 1 1 calc R . . . . C50 C 0.97931(18) 0.89401(15) 0.21009(11) 0.0770(5) Uani 1 1 d . U . . . H50 H 1.0090 0.8849 0.1569 0.092 Uiso 1 1 calc R . . . . C51 C 0.88900(16) 0.81361(12) 0.21221(9) 0.0676(4) Uani 1 1 d . U . . . H51 H 0.8561 0.7491 0.1608 0.081 Uiso 1 1 calc R . . . . H15 H 0.7477(12) 0.7484(9) 0.7432(8) 0.036(3) Uiso 1 1 d . . . . . H6A H 0.3790(12) 0.7127(8) 0.6992(8) 0.035(3) Uiso 1 1 d . . . . . H13 H 0.7461(11) 0.7466(8) 0.9925(8) 0.037(3) Uiso 1 1 d . . . . . H24 H 0.1156(13) 0.4635(10) 0.2013(8) 0.043(3) Uiso 1 1 d . . . . . H11 H 0.5158(13) 0.4945(9) 0.7504(8) 0.039(3) Uiso 1 1 d . . . . . H2 H 0.1482(12) 0.4561(9) 0.6969(8) 0.037(3) Uiso 1 1 d . . . . . H4 H 0.3792(12) 0.7063(9) 0.9441(8) 0.037(3) Uiso 1 1 d . . . . . H20 H -0.1240(12) 0.2161(9) -0.0408(9) 0.042(3) Uiso 1 1 d . . . . . H22 H -0.1153(13) 0.2148(9) 0.2077(9) 0.046(3) Uiso 1 1 d . . . . . H12 H 0.9759(15) 0.9723(10) 0.9126(10) 0.064(4) Uiso 1 1 d D . . . . H9 H 0.4566(15) 0.4454(11) 0.9187(9) 0.058(4) Uiso 1 1 d D . . . . H6 H 0.6025(17) 0.9345(11) 0.8741(11) 0.081(5) Uiso 1 1 d D . . . . H17 H -0.3486(16) -0.0102(11) 0.0358(11) 0.085(5) Uiso 1 1 d D . . . . H3 H 0.0737(18) 0.4118(13) 0.8677(11) 0.085(5) Uiso 1 1 d D . . . . H14 H 0.1819(15) 0.5123(10) 0.0323(9) 0.073(5) Uiso 1 1 d D . . . . H8 H 0.464(6) 0.448(3) 0.5341(14) 0.41(3) Uiso 1 1 d D . . . . H1 H 0.216(3) 0.5414(19) 0.4788(12) 0.163(10) Uiso 1 1 d D . . . . H16 H 0.048(3) 0.380(2) 0.4184(12) 0.178(12) Uiso 1 1 d D . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0559(4) 0.0391(4) 0.0228(3) 0.0158(3) 0.0109(3) 0.0045(3) O2 0.0508(4) 0.0396(4) 0.0248(3) 0.0111(3) 0.0029(3) -0.0070(3) O3 0.0484(4) 0.0345(4) 0.0304(3) 0.0172(3) 0.0076(3) -0.0037(3) O4 0.0533(4) 0.0367(4) 0.0241(3) 0.0166(3) 0.0083(3) 0.0040(3) O5 0.0518(4) 0.0308(3) 0.0246(3) 0.0099(3) 0.0058(3) -0.0001(3) O6 0.0502(4) 0.0290(3) 0.0308(3) 0.0149(3) 0.0116(3) 0.0011(3) C1 0.0289(4) 0.0301(4) 0.0207(4) 0.0110(3) 0.0071(3) 0.0060(3) C2 0.0289(4) 0.0279(4) 0.0235(4) 0.0116(3) 0.0069(3) 0.0050(3) C3 0.0279(4) 0.0280(4) 0.0235(4) 0.0136(3) 0.0078(3) 0.0068(3) C4 0.0293(4) 0.0291(4) 0.0211(4) 0.0118(3) 0.0067(3) 0.0077(3) C5 0.0274(4) 0.0254(4) 0.0239(4) 0.0113(3) 0.0071(3) 0.0060(3) C6 0.0306(4) 0.0297(4) 0.0227(4) 0.0138(3) 0.0082(3) 0.0066(3) C7 0.0333(4) 0.0316(4) 0.0219(4) 0.0127(3) 0.0074(3) 0.0056(3) C8 0.0320(4) 0.0279(4) 0.0241(4) 0.0135(3) 0.0088(3) 0.0070(3) C9 0.0316(4) 0.0261(4) 0.0241(4) 0.0117(3) 0.0074(3) 0.0063(3) O7 0.0512(4) 0.0386(4) 0.0235(3) 0.0162(3) 0.0069(3) -0.0020(3) O8 0.0498(4) 0.0312(3) 0.0242(3) 0.0085(3) 0.0047(3) -0.0064(3) O9 0.0515(4) 0.0286(3) 0.0285(3) 0.0148(3) 0.0087(3) -0.0055(3) O10 0.0518(4) 0.0351(4) 0.0234(3) 0.0149(3) 0.0080(3) -0.0024(3) O11 0.0515(4) 0.0263(3) 0.0240(3) 0.0083(3) 0.0063(3) -0.0037(3) O12 0.0467(4) 0.0240(3) 0.0287(3) 0.0127(3) 0.0098(3) -0.0017(3) C10 0.0278(4) 0.0248(4) 0.0197(4) 0.0102(3) 0.0059(3) 0.0043(3) C11 0.0285(4) 0.0232(4) 0.0230(4) 0.0112(3) 0.0064(3) 0.0037(3) C12 0.0275(4) 0.0240(4) 0.0232(4) 0.0126(3) 0.0071(3) 0.0042(3) C13 0.0282(4) 0.0246(4) 0.0206(4) 0.0106(3) 0.0064(3) 0.0048(3) C14 0.0263(4) 0.0210(4) 0.0224(4) 0.0095(3) 0.0063(3) 0.0038(3) C15 0.0293(4) 0.0243(4) 0.0229(4) 0.0123(3) 0.0072(3) 0.0052(3) C16 0.0326(4) 0.0254(4) 0.0204(4) 0.0099(3) 0.0054(3) 0.0033(3) C17 0.0317(4) 0.0259(4) 0.0239(4) 0.0135(3) 0.0076(3) 0.0034(3) C18 0.0297(4) 0.0220(4) 0.0236(4) 0.0105(3) 0.0066(3) 0.0039(3) O13 0.0539(4) 0.0413(4) 0.0245(3) 0.0176(3) 0.0105(3) 0.0042(3) O14 0.0541(4) 0.0311(3) 0.0304(4) 0.0170(3) 0.0112(3) 0.0015(3) O15 0.0513(4) 0.0339(3) 0.0235(3) 0.0092(3) 0.0055(3) 0.0037(3) O16 0.0517(4) 0.0494(4) 0.0251(3) 0.0208(3) 0.0072(3) 0.0019(3) O17 0.0499(4) 0.0304(3) 0.0324(4) 0.0147(3) 0.0121(3) 0.0002(3) O18 0.0560(4) 0.0315(3) 0.0266(3) 0.0076(3) 0.0108(3) -0.0006(3) C19 0.0312(4) 0.0277(4) 0.0227(4) 0.0132(3) 0.0098(3) 0.0096(3) C20 0.0327(4) 0.0289(4) 0.0218(4) 0.0119(3) 0.0089(3) 0.0091(3) C21 0.0303(4) 0.0243(4) 0.0243(4) 0.0107(3) 0.0082(3) 0.0067(3) C22 0.0318(4) 0.0288(4) 0.0241(4) 0.0139(3) 0.0093(3) 0.0090(3) C23 0.0308(4) 0.0295(4) 0.0207(4) 0.0121(3) 0.0082(3) 0.0096(3) C24 0.0316(4) 0.0255(4) 0.0229(4) 0.0111(3) 0.0079(3) 0.0083(3) C25 0.0345(4) 0.0276(4) 0.0235(4) 0.0129(3) 0.0101(3) 0.0092(3) C26 0.0345(5) 0.0272(4) 0.0257(4) 0.0122(3) 0.0091(3) 0.0073(3) C27 0.0337(4) 0.0306(4) 0.0219(4) 0.0126(3) 0.0073(3) 0.0079(3) O19 0.1539(12) 0.0685(7) 0.0637(7) 0.0427(6) -0.0065(7) 0.0007(7) C28 0.0739(9) 0.0527(7) 0.0560(7) 0.0293(6) 0.0129(6) 0.0191(6) C29 0.0904(10) 0.0439(6) 0.0518(7) 0.0239(5) 0.0161(7) 0.0227(6) C30 0.0875(10) 0.0698(9) 0.0586(8) 0.0369(7) 0.0195(7) 0.0318(8) C31 0.0629(9) 0.0796(10) 0.0561(8) 0.0216(7) 0.0047(6) 0.0161(7) C32 0.0510(7) 0.0558(8) 0.0847(10) 0.0235(7) 0.0082(7) 0.0029(6) C33 0.0620(8) 0.0535(7) 0.0866(10) 0.0400(7) 0.0135(7) 0.0132(6) C34 0.0977(12) 0.0656(8) 0.0451(7) 0.0316(6) 0.0064(7) 0.0175(8) C35 0.1077(13) 0.0756(10) 0.0561(8) 0.0299(8) 0.0272(8) 0.0378(10) C36 0.0855(11) 0.0853(11) 0.0596(9) 0.0317(8) 0.0125(8) 0.0252(9) C37 0.0983(12) 0.0708(9) 0.0436(7) 0.0165(7) -0.0090(7) 0.0240(9) C38 0.1124(15) 0.1014(13) 0.0434(7) 0.0273(8) 0.0127(8) 0.0599(12) C39 0.0821(11) 0.1141(14) 0.0546(8) 0.0491(9) 0.0150(8) 0.0380(10) O20 0.1037(9) 0.0487(5) 0.0750(7) 0.0077(5) 0.0375(6) 0.0098(5) C40 0.0671(8) 0.0393(6) 0.0725(9) 0.0207(6) 0.0216(7) 0.0098(6) C45 0.0782(10) 0.0804(11) 0.0960(12) 0.0504(9) 0.0231(9) 0.0339(9) C44 0.0856(12) 0.0928(13) 0.1267(16) 0.0622(12) 0.0532(12) 0.0443(10) C43 0.0998(13) 0.0627(9) 0.1001(13) 0.0459(9) 0.0487(11) 0.0174(9) C42 0.0850(11) 0.0513(8) 0.0922(11) 0.0441(8) 0.0137(9) 0.0001(7) C41 0.0583(8) 0.0446(7) 0.0961(11) 0.0344(7) 0.0157(8) 0.0074(6) C46 0.0575(7) 0.0557(7) 0.0473(7) 0.0172(6) 0.0122(5) 0.0182(6) C47 0.0640(8) 0.0528(7) 0.0410(6) 0.0173(5) 0.0145(5) 0.0096(6) C48 0.0830(10) 0.0609(8) 0.0512(7) 0.0246(6) 0.0143(7) 0.0035(7) C49 0.0814(11) 0.0957(12) 0.0712(10) 0.0529(10) 0.0267(8) 0.0179(9) C50 0.0877(11) 0.1139(14) 0.0562(9) 0.0506(9) 0.0331(8) 0.0535(10) C51 0.0793(10) 0.0810(10) 0.0421(7) 0.0220(6) 0.0159(6) 0.0416(8) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C7 1.2695(11) . ? O1 H1 0.917(17) . ? O2 C7 1.2566(11) . ? O3 C8 1.2917(11) . ? O3 H3 0.859(14) . ? O4 C8 1.2345(11) . ? O5 C9 1.2299(11) . ? O6 C9 1.2969(11) . ? O6 H6 0.917(14) . ? C1 C2 1.3945(12) . ? C1 C6 1.3957(12) . ? C1 C7 1.4882(12) . ? C2 C3 1.3905(12) . ? C2 H2 0.963(12) . ? C3 C4 1.3953(12) . ? C3 C8 1.4912(11) . ? C4 C5 1.3944(11) . ? C4 H4 0.979(12) . ? C5 C6 1.3873(12) . ? C5 C9 1.4947(11) . ? C6 H6A 0.971(12) . ? O7 C16 1.2375(11) . ? O8 C16 1.2904(11) . ? O8 H8 0.870(19) . ? O9 C17 1.2967(11) . ? O9 H9 0.894(12) . ? O10 C17 1.2325(11) . ? O11 C18 1.2239(11) . ? O12 C18 1.3090(10) . ? O12 H12 0.932(13) . ? C10 C11 1.3955(11) . ? C10 C15 1.3957(11) . ? C10 C16 1.4872(12) . ? C11 C12 1.3903(12) . ? C11 H11 0.958(13) . ? C12 C13 1.3956(11) . ? C12 C17 1.4912(11) . ? C13 C14 1.3911(11) . ? C13 H13 0.979(12) . ? C14 C15 1.3931(12) . ? C14 C18 1.4909(11) . ? C15 H15 1.006(12) . ? O13 C25 1.2318(11) . ? O14 C25 1.2988(11) . ? O14 H14 0.893(13) . ? O15 C27 1.2623(11) . ? O16 C27 1.2748(11) . ? O16 H16 0.812(17) . ? O17 C26 1.3002(11) . ? O17 H17 0.931(13) . ? O18 C26 1.2265(11) . ? C19 C20 1.3936(12) . ? C19 C24 1.3890(12) . ? C19 C25 1.4894(11) . ? C20 C21 1.3912(12) . ? C20 H20 0.991(13) . ? C21 C22 1.3886(12) . ? C21 C26 1.4932(12) . ? C22 C23 1.3982(12) . ? C22 H22 0.951(13) . ? C23 C24 1.3957(11) . ? C23 C27 1.4839(12) . ? C24 H24 0.937(13) . ? O19 C28 1.3792(17) . ? O19 C34 1.3906(18) . ? C28 C29 1.3769(18) . ? C28 C33 1.3782(19) . ? C29 H29 0.9500 . ? C29 C30 1.382(2) . ? C30 H30 0.9500 . ? C30 C31 1.383(2) . ? C31 H31 0.9500 . ? C31 C32 1.362(2) . ? C32 H32 0.9500 . ? C32 C33 1.369(2) . ? C33 H33 0.9500 . ? C34 C35 1.366(2) . ? C34 C39 1.382(3) . ? C35 H35 0.9500 . ? C35 C36 1.363(2) . ? C36 H36 0.9500 . ? C36 C37 1.364(2) . ? C37 H37 0.9500 . ? C37 C38 1.377(3) . ? C38 H38 0.9500 . ? C38 C39 1.394(3) . ? C39 H39 0.9500 . ? O20 C40 1.3665(13) . ? O20 C46 1.3765(17) . ? C40 C45 1.3900 . ? C40 C41 1.3900 . ? C45 H45 0.9500 . ? C45 C44 1.3900 . ? C44 H44 0.9500 . ? C44 C43 1.3900 . ? C43 H43 0.9500 . ? C43 C42 1.3900 . ? C42 H42 0.9500 . ? C42 C41 1.3900 . ? C41 H41 0.9500 . ? C46 C47 1.3792(18) . ? C46 C51 1.3836(19) . ? C47 H47 0.9500 . ? C47 C48 1.376(2) . ? C48 H48 0.9500 . ? C48 C49 1.382(2) . ? C49 H49 0.9500 . ? C49 C50 1.375(2) . ? C50 H50 0.9500 . ? C50 C51 1.370(2) . ? C51 H51 0.9500 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C7 O1 H1 113.7(18) . . ? C8 O3 H3 109.3(12) . . ? C9 O6 H6 106.9(11) . . ? C2 C1 C6 120.44(8) . . ? C2 C1 C7 119.37(8) . . ? C6 C1 C7 120.18(8) . . ? C1 C2 H2 118.7(7) . . ? C3 C2 C1 119.55(8) . . ? C3 C2 H2 121.7(7) . . ? C2 C3 C4 120.44(8) . . ? C2 C3 C8 120.85(8) . . ? C4 C3 C8 118.67(7) . . ? C3 C4 H4 120.2(7) . . ? C5 C4 C3 119.43(8) . . ? C5 C4 H4 120.4(7) . . ? C4 C5 C9 118.19(8) . . ? C6 C5 C4 120.64(8) . . ? C6 C5 C9 121.16(8) . . ? C1 C6 H6A 119.6(7) . . ? C5 C6 C1 119.49(8) . . ? C5 C6 H6A 120.9(7) . . ? O1 C7 C1 117.38(8) . . ? O2 C7 O1 124.42(8) . . ? O2 C7 C1 118.19(8) . . ? O3 C8 C3 115.45(7) . . ? O4 C8 O3 124.24(8) . . ? O4 C8 C3 120.29(8) . . ? O5 C9 O6 124.89(8) . . ? O5 C9 C5 120.06(8) . . ? O6 C9 C5 115.05(7) . . ? C16 O8 H8 108(3) . . ? C17 O9 H9 109.8(9) . . ? C18 O12 H12 113.0(9) . . ? C11 C10 C16 120.42(7) . . ? C15 C10 C11 120.58(8) . . ? C15 C10 C16 118.99(7) . . ? C10 C11 H11 121.6(7) . . ? C12 C11 C10 119.28(8) . . ? C12 C11 H11 119.1(7) . . ? C11 C12 C13 120.67(8) . . ? C11 C12 C17 120.60(7) . . ? C13 C12 C17 118.71(7) . . ? C12 C13 H13 119.3(7) . . ? C14 C13 C12 119.54(8) . . ? C14 C13 H13 121.2(7) . . ? C13 C14 C15 120.47(7) . . ? C13 C14 C18 118.26(7) . . ? C15 C14 C18 121.27(7) . . ? C10 C15 H15 119.0(7) . . ? C14 C15 C10 119.45(8) . . ? C14 C15 H15 121.5(7) . . ? O7 C16 O8 124.65(8) . . ? O7 C16 C10 120.33(8) . . ? O8 C16 C10 115.01(7) . . ? O9 C17 C12 114.82(7) . . ? O10 C17 O9 124.70(8) . . ? O10 C17 C12 120.47(8) . . ? O11 C18 O12 124.31(8) . . ? O11 C18 C14 120.92(8) . . ? O12 C18 C14 114.77(7) . . ? C25 O14 H14 110.9(9) . . ? C27 O16 H16 113(2) . . ? C26 O17 H17 109.4(11) . . ? C20 C19 C25 118.69(7) . . ? C24 C19 C20 120.33(8) . . ? C24 C19 C25 120.97(8) . . ? C19 C20 H20 119.1(7) . . ? C21 C20 C19 119.74(8) . . ? C21 C20 H20 121.2(7) . . ? C20 C21 C26 118.27(8) . . ? C22 C21 C20 120.53(8) . . ? C22 C21 C26 121.20(8) . . ? C21 C22 C23 119.46(8) . . ? C21 C22 H22 122.7(8) . . ? C23 C22 H22 117.8(8) . . ? C22 C23 C27 120.00(8) . . ? C24 C23 C22 120.29(8) . . ? C24 C23 C27 119.70(8) . . ? C19 C24 C23 119.65(8) . . ? C19 C24 H24 119.3(7) . . ? C23 C24 H24 121.0(7) . . ? O13 C25 O14 124.12(8) . . ? O13 C25 C19 120.59(8) . . ? O14 C25 C19 115.28(7) . . ? O17 C26 C21 114.77(8) . . ? O18 C26 O17 125.16(8) . . ? O18 C26 C21 120.06(8) . . ? O15 C27 O16 124.15(8) . . ? O15 C27 C23 118.49(8) . . ? O16 C27 C23 117.36(8) . . ? C28 O19 C34 118.44(11) . . ? C29 C28 O19 124.06(12) . . ? C29 C28 C33 120.42(13) . . ? C33 C28 O19 115.52(12) . . ? C28 C29 H29 120.5 . . ? C28 C29 C30 119.01(13) . . ? C30 C29 H29 120.5 . . ? C29 C30 H30 119.7 . . ? C29 C30 C31 120.53(14) . . ? C31 C30 H30 119.7 . . ? C30 C31 H31 120.3 . . ? C32 C31 C30 119.40(14) . . ? C32 C31 H31 120.3 . . ? C31 C32 H32 119.5 . . ? C31 C32 C33 120.91(14) . . ? C33 C32 H32 119.5 . . ? C28 C33 H33 120.1 . . ? C32 C33 C28 119.70(14) . . ? C32 C33 H33 120.1 . . ? C35 C34 O19 120.00(16) . . ? C35 C34 C39 121.94(16) . . ? C39 C34 O19 118.01(17) . . ? C34 C35 H35 120.2 . . ? C36 C35 C34 119.64(16) . . ? C36 C35 H35 120.2 . . ? C35 C36 H36 119.9 . . ? C35 C36 C37 120.16(18) . . ? C37 C36 H36 119.9 . . ? C36 C37 H37 119.7 . . ? C36 C37 C38 120.57(17) . . ? C38 C37 H37 119.7 . . ? C37 C38 H38 119.9 . . ? C37 C38 C39 120.21(17) . . ? C39 C38 H38 119.9 . . ? C34 C39 C38 117.46(17) . . ? C34 C39 H39 121.3 . . ? C38 C39 H39 121.3 . . ? C40 O20 C46 117.56(9) . . ? O20 C40 C45 119.86(9) . . ? O20 C40 C41 120.14(9) . . ? C45 C40 C41 120.0 . . ? C40 C45 H45 120.0 . . ? C40 C45 C44 120.0 . . ? C44 C45 H45 120.0 . . ? C45 C44 H44 120.0 . . ? C45 C44 C43 120.0 . . ? C43 C44 H44 120.0 . . ? C44 C43 H43 120.0 . . ? C44 C43 C42 120.0 . . ? C42 C43 H43 120.0 . . ? C43 C42 H42 120.0 . . ? C41 C42 C43 120.0 . . ? C41 C42 H42 120.0 . . ? C40 C41 H41 120.0 . . ? C42 C41 C40 120.0 . . ? C42 C41 H41 120.0 . . ? O20 C46 C47 123.84(12) . . ? O20 C46 C51 115.57(12) . . ? C47 C46 C51 120.59(14) . . ? C46 C47 H47 120.5 . . ? C48 C47 C46 119.09(13) . . ? C48 C47 H47 120.5 . . ? C47 C48 H48 119.6 . . ? C47 C48 C49 120.77(15) . . ? C49 C48 H48 119.6 . . ? C48 C49 H49 120.3 . . ? C50 C49 C48 119.34(15) . . ? C50 C49 H49 120.3 . . ? C49 C50 H50 119.6 . . ? C51 C50 C49 120.72(14) . . ? C51 C50 H50 119.6 . . ? C46 C51 H51 120.3 . . ? C50 C51 C46 119.48(14) . . ? C50 C51 H51 120.3 . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O12 H12 O11 0.932(13) 1.716(13) 2.6426(9) 172.7(15) 2_777 O9 H9 O10 0.894(12) 1.729(12) 2.6196(9) 174.0(14) 2_667 O6 H6 O18 0.917(14) 1.712(14) 2.6205(10) 170.6(17) 1_666 O17 H17 O5 0.931(13) 1.713(14) 2.6426(9) 176.4(16) 1_444 O3 H3 O13 0.859(14) 1.793(14) 2.6506(9) 176.1(18) 1_556 O14 H14 O4 0.893(13) 1.729(13) 2.6213(9) 176.4(14) 1_554 O8 H8 O7 0.870(19) 1.81(3) 2.6338(10) 158(6) 2_666 O1 H1 O15 0.917(17) 1.706(17) 2.6218(10) 176(3) . O16 H16 O2 0.812(17) 1.791(17) 2.5993(10) 173(3) . _shelx_res_file ; pc_ht_1_ii329_etoh_ph2o.res created by SHELXL-2014/7 TITL PC_HT_1_ii329.res in P-1 REM Old TITL shelxt in P -1 REM SHELXT solution in P-1 REM R1 0.167, Rweak 0.002, Alpha 0.063, Orientation as input REM Formula found by SHELXT: C53 O18 CELL 0.6889 10.5024 15.8859 16.6093 113.726 98.448 106.802 ZERR 2 0.000056 0.000074 0.000071 0.000376 0.000425 0.00042 LATT 1 SFAC C H O DISP C 0.0028 0.0015 10.64 DISP H -0 0 0.67 DISP O 0.0101 0.0057 29.59 UNIT 102 76 40 EQIV $1 +X,+Y,1+Z EQIV $2 1+X,1+Y,1+Z EQIV $3 1-X,1-Y,1-Z EQIV $4 1-X,1-Y,2-Z EQIV $5 2-X,2-Y,2-Z EQIV $6 +X,+Y,-1+Z EQIV $7 -1+X,-1+Y,-1+Z DFIX 0.82 O17 H17 O14 H14 O1 H1 O16 H16 O8 H8 O9 H9 O3 H3 O12 H12 O6 H6 DANG 1.79 C16 H8 RIGU O20 C40 C46 C41 C45 C47 C51 C42 C44 C48 C50 C43 C49 RIGU O19 C28 C34 C29 C33 C35 C39 C30 C32 C36 C38 C31 C37 L.S. 30 PLAN 20 SIZE 0.078 0.028 0.024 TEMP -73.15 HTAB O1 O15 HTAB O3 O13_$1 HTAB O6 O18_$2 HTAB O8 O7_$3 HTAB O9 O10_$4 HTAB O12 O11_$5 HTAB O14 O4_$6 HTAB O16 O2 HTAB O17 O5_$7 BOND $H LIST 6 fmap 2 acta SHEL 999 0.73 OMIT -1 -2 6 OMIT -2 -1 5 REM REM REM WGHT 0.090000 FVAR 0.30138 O1 3 0.258007 0.573410 0.541348 11.00000 0.05586 0.03909 = 0.02282 0.01581 0.01090 0.00448 O2 3 0.108120 0.441257 0.541889 11.00000 0.05082 0.03965 = 0.02478 0.01112 0.00289 -0.00699 O3 3 0.100326 0.435175 0.831898 11.00000 0.04837 0.03446 = 0.03040 0.01722 0.00758 -0.00372 O4 3 0.250032 0.561889 0.965195 11.00000 0.05332 0.03667 = 0.02406 0.01662 0.00826 0.00400 O5 3 0.531100 0.870653 0.967390 11.00000 0.05180 0.03081 = 0.02459 0.00989 0.00575 -0.00010 O6 3 0.541994 0.870471 0.833621 11.00000 0.05018 0.02895 = 0.03082 0.01494 0.01158 0.00105 C1 1 0.255674 0.577521 0.684668 11.00000 0.02892 0.03012 = 0.02073 0.01101 0.00707 0.00598 C2 1 0.209068 0.525402 0.731972 11.00000 0.02890 0.02790 = 0.02346 0.01164 0.00694 0.00501 C3 1 0.254620 0.573415 0.827829 11.00000 0.02789 0.02800 = 0.02347 0.01361 0.00780 0.00682 C4 1 0.348080 0.672583 0.876634 11.00000 0.02926 0.02909 = 0.02108 0.01184 0.00669 0.00772 C5 1 0.394380 0.723714 0.828484 11.00000 0.02743 0.02543 = 0.02388 0.01125 0.00706 0.00600 C6 1 0.348380 0.676949 0.732882 11.00000 0.03064 0.02974 = 0.02273 0.01379 0.00817 0.00665 C7 1 0.203242 0.526784 0.582170 11.00000 0.03327 0.03164 = 0.02189 0.01266 0.00737 0.00557 C8 1 0.201040 0.521396 0.880531 11.00000 0.03200 0.02785 = 0.02406 0.01348 0.00880 0.00704 C9 1 0.495946 0.829431 0.882631 11.00000 0.03162 0.02608 = 0.02406 0.01166 0.00744 0.00627 O7 3 0.623804 0.605189 0.587291 11.00000 0.05121 0.03860 = 0.02349 0.01618 0.00692 -0.00201 O8 3 0.476129 0.475644 0.593214 11.00000 0.04982 0.03123 = 0.02415 0.00849 0.00469 -0.00640 O9 3 0.483719 0.470749 0.881870 11.00000 0.05149 0.02858 = 0.02846 0.01476 0.00871 -0.00547 O10 3 0.613568 0.606383 1.016237 11.00000 0.05177 0.03506 = 0.02339 0.01486 0.00804 -0.00235 O11 3 0.899427 0.911334 1.013002 11.00000 0.05151 0.02631 = 0.02401 0.00828 0.00634 -0.00368 O12 3 0.911640 0.906811 0.877895 11.00000 0.04670 0.02397 = 0.02869 0.01271 0.00983 -0.00167 C10 1 0.625471 0.613541 0.732988 11.00000 0.02779 0.02477 = 0.01969 0.01022 0.00593 0.00435 C11 1 0.579326 0.562762 0.781524 11.00000 0.02853 0.02322 = 0.02302 0.01119 0.00644 0.00365 C12 1 0.624538 0.612881 0.877372 11.00000 0.02752 0.02403 = 0.02320 0.01259 0.00713 0.00420 C13 1 0.716155 0.712600 0.924971 11.00000 0.02822 0.02455 = 0.02062 0.01057 0.00644 0.00483 C14 1 0.763416 0.761939 0.875848 11.00000 0.02632 0.02097 = 0.02241 0.00954 0.00626 0.00379 C15 1 0.718154 0.712991 0.779801 11.00000 0.02925 0.02426 = 0.02289 0.01234 0.00722 0.00515 C16 1 0.574212 0.563012 0.630534 11.00000 0.03263 0.02536 = 0.02037 0.00990 0.00543 0.00330 C17 1 0.572904 0.561909 0.931276 11.00000 0.03169 0.02590 = 0.02392 0.01354 0.00762 0.00344 C18 1 0.864516 0.867519 0.928669 11.00000 0.02972 0.02198 = 0.02361 0.01047 0.00657 0.00390 O13 3 0.008029 0.356399 -0.064025 11.00000 0.05395 0.04132 = 0.02451 0.01759 0.01054 0.00423 O14 3 0.152073 0.487597 0.068882 11.00000 0.05406 0.03106 = 0.03040 0.01699 0.01115 0.00150 O15 3 0.150799 0.485648 0.361679 11.00000 0.05129 0.03394 = 0.02355 0.00916 0.00551 0.00370 O16 3 0.012521 0.349358 0.362952 11.00000 0.05175 0.04937 = 0.02506 0.02084 0.00716 0.00189 O17 3 -0.287769 0.055728 0.073742 11.00000 0.04995 0.03037 = 0.03242 0.01469 0.01207 0.00017 O18 3 -0.266225 0.049657 -0.060654 11.00000 0.05600 0.03154 = 0.02660 0.00757 0.01078 -0.00056 C19 1 0.004572 0.348062 0.074798 11.00000 0.03124 0.02774 = 0.02268 0.01322 0.00981 0.00964 C20 1 -0.090686 0.249533 0.027516 11.00000 0.03266 0.02887 = 0.02185 0.01185 0.00887 0.00911 C21 1 -0.136694 0.199719 0.076530 11.00000 0.03032 0.02432 = 0.02428 0.01067 0.00815 0.00666 C22 1 -0.088824 0.247490 0.172209 11.00000 0.03181 0.02882 = 0.02410 0.01387 0.00934 0.00896 C23 1 0.006536 0.346409 0.219267 11.00000 0.03077 0.02952 = 0.02075 0.01208 0.00824 0.00964 C24 1 0.053094 0.396809 0.170502 11.00000 0.03160 0.02551 = 0.02293 0.01109 0.00793 0.00830 C25 1 0.055536 0.398718 0.020633 11.00000 0.03451 0.02760 = 0.02351 0.01286 0.01007 0.00923 C26 1 -0.237782 0.093936 0.023552 11.00000 0.03450 0.02717 = 0.02569 0.01217 0.00914 0.00731 C27 1 0.060580 0.397707 0.321421 11.00000 0.03369 0.03056 = 0.02187 0.01256 0.00730 0.00795 O19 3 0.356967 0.907215 0.671334 11.00000 0.15395 0.06847 = 0.06367 0.04274 -0.00650 0.00067 C28 1 0.295527 0.875662 0.579511 11.00000 0.07392 0.05273 = 0.05600 0.02929 0.01294 0.01914 C29 1 0.309600 0.937731 0.539828 11.00000 0.09038 0.04386 = 0.05177 0.02389 0.01610 0.02275 AFIX 43 H29 2 0.365727 1.006791 0.575487 11.00000 -1.20000 AFIX 0 C30 1 0.240873 0.898074 0.447374 11.00000 0.08746 0.06975 = 0.05855 0.03692 0.01950 0.03182 AFIX 43 H30 2 0.248343 0.940419 0.419552 11.00000 -1.20000 AFIX 0 C31 1 0.161274 0.797203 0.394996 11.00000 0.06286 0.07958 = 0.05607 0.02158 0.00472 0.01611 AFIX 43 H31 2 0.114247 0.770180 0.331426 11.00000 -1.20000 AFIX 0 C32 1 0.150927 0.736974 0.435386 11.00000 0.05105 0.05583 = 0.08474 0.02350 0.00817 0.00288 AFIX 43 H32 2 0.098231 0.667429 0.399203 11.00000 -1.20000 AFIX 0 C33 1 0.215428 0.775281 0.527418 11.00000 0.06201 0.05350 = 0.08657 0.03996 0.01346 0.01323 AFIX 43 H33 2 0.205017 0.732860 0.555240 11.00000 -1.20000 AFIX 0 C34 1 0.443485 1.006983 0.727007 11.00000 0.09769 0.06557 = 0.04513 0.03159 0.00640 0.01746 C35 1 0.578436 1.040513 0.726216 11.00000 0.10769 0.07558 = 0.05613 0.02989 0.02715 0.03782 AFIX 43 H35 2 0.612757 0.996190 0.686580 11.00000 -1.20000 AFIX 0 C36 1 0.663566 1.137925 0.782618 11.00000 0.08546 0.08532 = 0.05958 0.03173 0.01251 0.02516 AFIX 43 H36 2 0.757147 1.161723 0.781781 11.00000 -1.20000 AFIX 0 C37 1 0.614692 1.201288 0.840241 11.00000 0.09826 0.07084 = 0.04365 0.01648 -0.00898 0.02401 AFIX 43 H37 2 0.674639 1.269033 0.879451 11.00000 -1.20000 AFIX 0 C38 1 0.479235 1.167917 0.842072 11.00000 0.11240 0.10141 = 0.04343 0.02726 0.01274 0.05989 AFIX 43 H38 2 0.446280 1.212646 0.882528 11.00000 -1.20000 AFIX 0 C39 1 0.390265 1.068677 0.784734 11.00000 0.08210 0.11414 = 0.05456 0.04911 0.01497 0.03804 AFIX 43 H39 2 0.296632 1.044392 0.785325 11.00000 -1.20000 AFIX 0 O20 3 0.756039 0.742263 0.286176 11.00000 0.10372 0.04870 = 0.07505 0.00775 0.03745 0.00977 AFIX 66 C40 1 0.706066 0.752715 0.359642 11.00000 0.06706 0.03926 = 0.07247 0.02072 0.02164 0.00984 C45 1 0.581241 0.766497 0.359523 11.00000 0.07816 0.08041 = 0.09598 0.05041 0.02307 0.03393 AFIX 43 H45 2 0.531551 0.769602 0.308846 11.00000 -1.20000 AFIX 65 C44 1 0.529119 0.775735 0.433554 11.00000 0.08557 0.09276 = 0.12670 0.06218 0.05318 0.04428 AFIX 43 H44 2 0.443807 0.785154 0.433472 11.00000 -1.20000 AFIX 65 C43 1 0.601823 0.771191 0.507703 11.00000 0.09980 0.06273 = 0.10010 0.04587 0.04871 0.01740 AFIX 43 H43 2 0.566200 0.777505 0.558299 11.00000 -1.20000 AFIX 65 C42 1 0.726648 0.757410 0.507823 11.00000 0.08496 0.05130 = 0.09217 0.04408 0.01365 0.00006 AFIX 43 H42 2 0.776337 0.754305 0.558501 11.00000 -1.20000 AFIX 65 C41 1 0.778771 0.748172 0.433793 11.00000 0.05825 0.04462 = 0.09605 0.03442 0.01572 0.00739 AFIX 43 H41 2 0.864084 0.738753 0.433874 11.00000 -1.20000 AFIX 0 C46 1 0.846106 0.827086 0.289816 11.00000 0.05747 0.05574 = 0.04729 0.01723 0.01216 0.01823 C47 1 0.893020 0.920527 0.364573 11.00000 0.06396 0.05276 = 0.04100 0.01730 0.01448 0.00958 AFIX 43 H47 2 0.863736 0.929574 0.417886 11.00000 -1.20000 AFIX 0 C48 1 0.982821 1.000464 0.360879 11.00000 0.08299 0.06087 = 0.05124 0.02461 0.01431 0.00350 AFIX 43 H48 2 1.014508 1.065226 0.411709 11.00000 -1.20000 AFIX 0 C49 1 1.027461 0.987647 0.284093 11.00000 0.08144 0.09566 = 0.07120 0.05293 0.02668 0.01786 AFIX 43 H49 2 1.090793 1.042987 0.282457 11.00000 -1.20000 AFIX 0 C50 1 0.979306 0.894008 0.210088 11.00000 0.08771 0.11395 = 0.05616 0.05057 0.03313 0.05347 AFIX 43 H50 2 1.008961 0.884948 0.156902 11.00000 -1.20000 AFIX 0 C51 1 0.888999 0.813608 0.212214 11.00000 0.07928 0.08101 = 0.04208 0.02197 0.01593 0.04160 AFIX 43 H51 2 0.856106 0.749126 0.160813 11.00000 -1.20000 AFIX 0 H15 2 0.747651 0.748381 0.743205 11.00000 0.03611 H6A 2 0.379029 0.712660 0.699173 11.00000 0.03545 H13 2 0.746101 0.746575 0.992480 11.00000 0.03657 H24 2 0.115624 0.463518 0.201342 11.00000 0.04322 H11 2 0.515805 0.494512 0.750413 11.00000 0.03900 H2 2 0.148178 0.456072 0.696939 11.00000 0.03681 H4 2 0.379207 0.706272 0.944113 11.00000 0.03655 H20 2 -0.123973 0.216061 -0.040805 11.00000 0.04190 H22 2 -0.115336 0.214833 0.207707 11.00000 0.04633 H12 2 0.975887 0.972347 0.912616 11.00000 0.06416 H9 2 0.456571 0.445405 0.918661 11.00000 0.05835 H6 2 0.602480 0.934476 0.874088 11.00000 0.08134 H17 2 -0.348562 -0.010224 0.035809 11.00000 0.08455 H3 2 0.073689 0.411772 0.867726 11.00000 0.08549 H14 2 0.181862 0.512325 0.032315 11.00000 0.07276 H8 2 0.464121 0.447910 0.534148 11.00000 0.40577 H1 2 0.216325 0.541417 0.478839 11.00000 0.16307 H16 2 0.048330 0.379953 0.418445 11.00000 0.17773 HKLF 4 REM PC_HT_1_ii329.res in P-1 REM R1 = 0.0429 for 8999 Fo > 4sig(Fo) and 0.0559 for all 12320 data REM 700 parameters refined using 196 restraints END WGHT 0.0885 0.0273 REM Highest difference peak 0.306, deepest hole -0.380, 1-sigma level 0.110 Q1 1 0.4350 0.9191 0.6481 11.00000 0.05 0.31 Q2 1 0.6375 0.7700 0.5011 11.00000 0.05 0.30 Q3 1 0.4368 0.7714 0.8516 11.00000 0.05 0.27 Q4 1 0.5991 0.5856 0.9028 11.00000 0.05 0.26 Q5 1 0.9762 0.8496 0.2334 11.00000 0.05 0.26 Q6 1 0.6425 0.7719 0.3669 11.00000 0.05 0.25 Q7 1 0.5081 1.0321 0.6996 11.00000 0.05 0.25 Q8 1 0.6059 0.5902 0.7561 11.00000 0.05 0.24 Q9 1 0.8087 0.8102 0.8967 11.00000 0.05 0.24 Q10 1 0.5963 1.0997 0.7387 11.00000 0.05 0.24 Q11 1 0.5588 0.7473 0.3957 11.00000 0.05 0.24 Q12 1 -0.1840 0.1506 0.0509 11.00000 0.05 0.23 Q13 1 0.3035 0.8076 0.5379 11.00000 0.05 0.23 Q14 1 0.8038 0.9507 0.4253 11.00000 0.05 0.23 Q15 1 0.1544 0.6473 0.3861 11.00000 0.05 0.22 Q16 1 0.6452 0.8031 0.6095 11.00000 0.05 0.22 Q17 1 0.5854 0.7779 0.4583 11.00000 0.05 0.22 Q18 1 0.2365 0.5483 0.8558 11.00000 0.05 0.21 Q19 1 0.9421 1.0970 0.3034 11.00000 0.05 0.21 Q20 1 0.3601 0.8875 0.5586 11.00000 0.05 0.21 ; _shelx_res_checksum 8088 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_8-35_butanol-1-3-dimethoxybenzene_publ _database_code_depnum_ccdc_archive 'CCDC 1915314' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2018-07-02 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6, 5.38(H2 O)' _chemical_formula_sum 'C9 H16.75 O11.38' _chemical_formula_weight 306.97 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 12 _space_group_name_H-M_alt 'C 1 2/m 1' _space_group_name_Hall '-C 2y' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z' '-x, -y, -z' 'x, -y, z' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z' _cell_length_a 25.768(4) _cell_length_b 16.425(2) _cell_length_c 3.6006(5) _cell_angle_alpha 90 _cell_angle_beta 93.333(4) _cell_angle_gamma 90 _cell_volume 1521.3(4) _cell_formula_units_Z 4 _cell_measurement_reflns_used 3371 _cell_measurement_temperature 100 _cell_measurement_theta_max 26.450 _cell_measurement_theta_min 2.480 _shelx_estimated_absorpt_T_max 0.987 _shelx_estimated_absorpt_T_min 0.974 _exptl_absorpt_coefficient_mu 0.127 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4482 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2008/1 (Bruker,2008) was used for absorption correction. wR2(int) was 0.1020 before and 0.0711 after correction. The Ratio of minimum to maximum transmission is 0.6013. The \l/2 correction factor is 0.0015.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.340 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 647 _exptl_crystal_size_max 0.21 _exptl_crystal_size_mid 0.11 _exptl_crystal_size_min 0.1 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0521 _diffrn_reflns_av_unetI/netI 0.0433 _diffrn_reflns_Laue_measured_fraction_full 0.994 _diffrn_reflns_Laue_measured_fraction_max 0.994 _diffrn_reflns_limit_h_max 27 _diffrn_reflns_limit_h_min -32 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 4 _diffrn_reflns_limit_l_min -4 _diffrn_reflns_number 8267 _diffrn_reflns_point_group_measured_fraction_full 0.994 _diffrn_reflns_point_group_measured_fraction_max 0.994 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.371 _diffrn_reflns_theta_min 2.480 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.994 _diffrn_measured_fraction_theta_max 0.994 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 1293 _reflns_number_total 1618 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v7.68A (Bruker, 2009)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v7.68A (Bruker, 2009)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'ShelXT (Sheldrick, 2015)' _refine_diff_density_max 0.588 _refine_diff_density_min -0.433 _refine_diff_density_rms 0.118 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.785 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 115 _refine_ls_number_reflns 1618 _refine_ls_number_restraints 0 _refine_ls_R_factor_all 0.1014 _refine_ls_R_factor_gt 0.0887 _refine_ls_restrained_S_all 1.785 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1000P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.2374 _refine_ls_wR_factor_ref 0.2458 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All O(H) groups 2. Others Fixed Sof: H1(0.5) O1W(0.25) O2W(0.25) O3W(0.25) O4W(0.25) O5W(0.5) O6W(0.25) O7W(0.5) O8W(0.25) O9W(0.125) O10W(0.0625) 3.a Aromatic/amide H refined with riding coordinates: C3(H3), C6(H6) 3.b Idealised tetrahedral OH refined as rotating group: O1(H1), O2(H2) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.45458(7) 0.56825(12) 0.8180(6) 0.0373(6) Uani 1 1 d . . . . . H1 H 0.4855 0.5613 0.8999 0.056 Uiso 0.5 1 calc GR . . . . O2 O 0.30514(7) 0.71676(11) 0.2787(5) 0.0335(6) Uani 1 1 d . . . . . H2 H 0.2902 0.7575 0.1808 0.050 Uiso 1 1 calc GR . . . . O3 O 0.23999(6) 0.65025(11) -0.0300(5) 0.0311(6) Uani 1 1 d . . . . . C1 C 0.43416(12) 0.5000 0.7382(9) 0.0236(8) Uani 1 2 d S T P . . C2 C 0.38133(12) 0.5000 0.5434(9) 0.0238(8) Uani 1 2 d S T P . . C3 C 0.35683(10) 0.57359(15) 0.4546(7) 0.0246(6) Uani 1 1 d . . . . . H3 H 0.3737 0.6237 0.5155 0.030 Uiso 1 1 calc R . . . . C4 C 0.30752(9) 0.57324(14) 0.2761(7) 0.0227(6) Uani 1 1 d . . . . . C5 C 0.28131(9) 0.65110(15) 0.1646(7) 0.0244(6) Uani 1 1 d . . . . . C6 C 0.28262(13) 0.5000 0.1860(9) 0.0227(7) Uani 1 2 d S T P . . H6 H 0.2489 0.5000 0.0639 0.027 Uiso 1 2 calc RS T P . . O1W O 0.1500(12) 0.5000 0.498(9) 0.289(19) Uani 0.5 2 d S T P A 1 O2W O 0.1465(6) 0.5000 0.056(10) 0.225(11) Uani 0.5 2 d S T P B 2 O3W O 0.1182(19) 0.581(3) -0.014(12) 0.233(15) Uiso 0.25 1 d . . . C 3 O4W O 0.489(2) 0.763(4) 1.249(13) 0.30(2) Uiso 0.25 1 d . . . D 4 O5W O 0.4202(13) 0.783(2) 0.809(13) 0.307(15) Uiso 0.5 1 d . . . E 5 O6W O 0.4270(12) 0.774(2) 1.059(14) 0.171(10) Uiso 0.25 1 d . . . F 6 O7W O 0.4300(7) 0.7760(12) 0.419(8) 0.212(6) Uiso 0.5 1 d . . . G 7 O8W O 0.3949(16) 0.877(2) 0.581(11) 0.217(13) Uiso 0.25 1 d . . . H 8 O9W O 0.4963(17) 1.0000 0.345(9) 0.178(15) Uiso 0.25 2 d S T P I 9 O10W O 0.5000 1.0000 0.0000 0.22(3) Uiso 0.25 4 d S T P J 10 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0269(10) 0.0407(13) 0.0425(12) 0.0004(9) -0.0147(8) -0.0063(8) O2 0.0348(10) 0.0219(11) 0.0418(11) 0.0008(8) -0.0135(8) -0.0013(8) O3 0.0277(10) 0.0274(11) 0.0365(10) -0.0001(7) -0.0136(7) 0.0022(7) C1 0.0204(15) 0.0274(19) 0.0224(16) 0.000 -0.0031(12) 0.000 C2 0.0196(16) 0.0306(19) 0.0205(15) 0.000 -0.0039(12) 0.000 C3 0.0254(12) 0.0269(14) 0.0210(11) -0.0011(9) -0.0037(9) -0.0035(9) C4 0.0243(12) 0.0224(14) 0.0209(11) -0.0008(9) -0.0038(9) 0.0007(9) C5 0.0239(12) 0.0242(14) 0.0244(12) 0.0002(9) -0.0045(9) -0.0010(9) C6 0.0217(15) 0.0254(18) 0.0204(15) 0.000 -0.0058(12) 0.000 O1W 0.17(2) 0.48(6) 0.20(3) 0.000 -0.07(2) 0.000 O2W 0.060(7) 0.24(3) 0.37(4) 0.000 -0.016(13) 0.000 _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 H1 0.8400 . ? O1 C1 1.264(2) . ? O2 H2 0.8400 . ? O2 C5 1.296(3) . ? O3 C5 1.240(3) . ? C1 O1 1.264(2) 6_565 ? C1 C2 1.495(4) . ? C2 C3 1.392(3) 6_565 ? C2 C3 1.392(3) . ? C3 H3 0.9500 . ? C3 C4 1.390(4) . ? C4 C5 1.490(3) . ? C4 C6 1.393(3) . ? C6 C4 1.393(3) 6_565 ? C6 H6 0.9500 . ? O9W O9W 1.12(7) 5_676 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C1 O1 H1 109.5 . . ? C5 O2 H2 109.5 . . ? O1 C1 O1 124.9(3) . 6_565 ? O1 C1 C2 117.53(16) . . ? O1 C1 C2 117.54(16) 6_565 . ? C3 C2 C1 119.75(15) . . ? C3 C2 C1 119.76(15) 6_565 . ? C3 C2 C3 120.5(3) . 6_565 ? C2 C3 H3 120.2 . . ? C4 C3 C2 119.5(2) . . ? C4 C3 H3 120.2 . . ? C3 C4 C5 120.6(2) . . ? C3 C4 C6 120.5(2) . . ? C6 C4 C5 118.9(2) . . ? O2 C5 C4 115.5(2) . . ? O3 C5 O2 124.3(2) . . ? O3 C5 C4 120.2(2) . . ? C4 C6 C4 119.5(3) . 6_565 ? C4 C6 H6 120.3 6_565 . ? C4 C6 H6 120.3 . . ? _shelx_res_file ; pc_ht_1_i836.res created by SHELXL-2014/7 TITL pc_ht_1_i836_a.res in C2/m REM Old TITL pc_ht_1_i836_a.res in C2/m REM SHELXT solution in C2/m REM R1 0.195, Rweak 0.008, Alpha 0.072, Orientation as input REM Formula found by SHELXT: C9 O6 CELL 0.71073 25.7678 16.4251 3.6006 90 93.333 90 ZERR 4 0.0035 0.0024 0.0005 0 0.004 0 LATT 7 SYMM -X,+Y,-Z SFAC C H O UNIT 36 67 45.5 L.S. 20 PLAN 20 SIZE 0.21 0.1 0.11 TEMP -173.15 BOND $H list 4 fmap 2 53 acta SHEL 999 0.8 OMIT 9 3 0 OMIT 1 1 0 REM REM REM WGHT 0.100000 FVAR 0.60450 O1 3 0.454584 0.568245 0.817966 11.00000 0.02689 0.04069 = 0.04247 0.00042 -0.01466 -0.00632 AFIX 147 H1 2 0.485460 0.561343 0.899898 10.50000 -1.50000 AFIX 0 O2 3 0.305137 0.716759 0.278668 11.00000 0.03478 0.02192 = 0.04184 0.00081 -0.01355 -0.00134 AFIX 147 H2 2 0.290180 0.757542 0.180822 11.00000 -1.50000 AFIX 0 O3 3 0.239992 0.650254 -0.030038 11.00000 0.02766 0.02739 = 0.03648 -0.00008 -0.01356 0.00216 C1 1 0.434162 0.500000 0.738236 10.50000 0.02043 0.02744 = 0.02235 0.00000 -0.00305 0.00000 C2 1 0.381332 0.500000 0.543415 10.50000 0.01962 0.03065 = 0.02050 0.00000 -0.00387 0.00000 C3 1 0.356829 0.573590 0.454605 11.00000 0.02536 0.02691 = 0.02103 -0.00105 -0.00368 -0.00349 AFIX 43 H3 2 0.373685 0.623678 0.515517 11.00000 -1.20000 AFIX 0 C4 1 0.307517 0.573239 0.276146 11.00000 0.02430 0.02236 = 0.02087 -0.00081 -0.00381 0.00068 C5 1 0.281308 0.651105 0.164638 11.00000 0.02385 0.02421 = 0.02437 0.00016 -0.00450 -0.00098 C6 1 0.282615 0.500000 0.185951 10.50000 0.02167 0.02536 = 0.02036 0.00000 -0.00577 0.00000 AFIX 43 H6 2 0.248922 0.500001 0.063907 10.50000 -1.20000 AFIX 0 PART 1 O1W 3 0.150037 0.500000 0.497519 10.25000 0.17023 0.48241 = 0.20470 0.00000 -0.06766 0.00000 PART 0 PART 2 O2W 3 0.146535 0.500000 0.055983 10.25000 0.05978 0.24479 = 0.36678 0.00000 -0.01572 0.00000 PART 0 PART 3 O3W 3 0.118191 0.580645 -0.014114 10.25000 0.23279 PART 0 PART 4 O4W 3 0.489455 0.762799 1.248613 10.25000 0.29628 PART 0 PART 5 O5W 3 0.420217 0.783336 0.809377 10.50000 0.30704 PART 0 PART 6 O6W 3 0.427021 0.774464 1.059245 10.25000 0.17091 PART 0 PART 7 O7W 3 0.430014 0.776043 0.418899 10.50000 0.21234 PART 0 PART 8 O8W 3 0.394916 0.876548 0.581461 10.25000 0.21720 PART 0 PART 9 O9W 3 0.496335 1.000000 0.345431 10.12500 0.17819 PART 0 PART 10 O10W 3 0.500000 1.000000 0.000000 10.06250 0.22186 HKLF 4 REM pc_ht_1_i836_a.res in C2/m REM R1 = 0.0887 for 1293 Fo > 4sig(Fo) and 0.1014 for all 1618 data REM 115 parameters refined using 0 restraints END WGHT 0.1853 1.4093 REM Highest difference peak 0.588, deepest hole -0.433, 1-sigma level 0.118 Q1 1 0.5210 0.7615 1.0541 11.00000 0.05 0.53 Q2 1 0.0994 0.5000 0.4017 10.50000 0.05 0.51 Q3 1 0.3776 0.9152 0.5009 11.00000 0.05 0.46 Q4 1 0.3381 0.5000 0.3476 10.50000 0.05 0.46 Q5 1 0.4236 0.7822 0.6993 11.00000 0.05 0.45 Q6 1 0.3888 0.8847 0.3062 11.00000 0.05 0.45 Q7 1 0.4014 0.8484 0.6102 11.00000 0.05 0.44 Q8 1 0.4217 0.9205 0.6913 11.00000 0.05 0.43 Q9 1 0.3969 0.8538 0.7763 11.00000 0.05 0.43 Q10 1 0.3991 0.8393 0.9886 11.00000 0.05 0.43 Q11 1 0.3032 0.5935 0.2216 11.00000 0.05 0.42 Q12 1 0.2786 0.8053 0.1269 11.00000 0.05 0.40 Q13 1 0.4786 1.0734 -0.0933 11.00000 0.05 0.36 Q14 1 0.2587 0.5776 0.0361 11.00000 0.05 0.34 Q15 1 0.3830 0.6559 0.5548 11.00000 0.05 0.34 Q16 1 0.4517 1.0000 -0.1702 10.50000 0.05 0.32 Q17 1 0.4374 0.9623 0.6595 11.00000 0.05 0.31 Q18 1 0.3783 0.9057 0.7442 11.00000 0.05 0.31 Q19 1 0.3374 0.6527 0.3657 11.00000 0.05 0.30 Q20 1 0.3605 0.7198 0.4339 11.00000 0.05 0.29 ; _shelx_res_checksum 97662 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_tma_8-32_butanol_mesitylene_100k _database_code_depnum_ccdc_archive 'CCDC 1915313' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2019-02-11 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety '2(C9 H6 O6), 8(O)' _chemical_formula_sum 'C18 H12 O20' _chemical_formula_weight 548.28 _chemical_absolute_configuration ? _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system trigonal _space_group_IT_number 154 _space_group_name_H-M_alt 'P 32 2 1' _space_group_name_Hall 'P 32 2"' loop_ _space_group_symop_operation_xyz 'x, y, z' '-y, x-y, z+2/3' '-x+y, -x, z+1/3' 'x-y, -y, -z+1/3' '-x, -x+y, -z+2/3' 'y, x, -z' _cell_length_a 16.5230(16) _cell_length_b 16.5230(16) _cell_length_c 19.400(2) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 120 _cell_volume 4586.9(10) _cell_formula_units_Z 6 _cell_measurement_reflns_used 7663 _cell_measurement_temperature 100 _cell_measurement_theta_max 26.13 _cell_measurement_theta_min 2.47 _shelx_estimated_absorpt_T_max 0.996 _shelx_estimated_absorpt_T_min 0.985 _exptl_absorpt_coefficient_mu 0.113 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4679 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS Estimated minimum and maximum transmission: 0.4679 0.7454 The ratio of these values is more reliable than their absolute values! Additional spherical absorption correction applied with mu*r = 0.2000 Lambda/2 correction factor = 0.00150 ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.191 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 1680 _exptl_crystal_size_max 0.134 _exptl_crystal_size_mid 0.063 _exptl_crystal_size_min 0.039 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0919 _diffrn_reflns_av_unetI/netI 0.0909 _diffrn_reflns_Laue_measured_fraction_full 0.998 _diffrn_reflns_Laue_measured_fraction_max 0.999 _diffrn_reflns_limit_h_max 20 _diffrn_reflns_limit_h_min -19 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 20 _diffrn_reflns_limit_l_min -24 _diffrn_reflns_number 25344 _diffrn_reflns_point_group_measured_fraction_full 0.999 _diffrn_reflns_point_group_measured_fraction_max 0.999 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.373 _diffrn_reflns_theta_min 1.050 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.998 _diffrn_measured_fraction_theta_max 0.999 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.809 _reflns_Friedel_fraction_full 1.000 _reflns_Friedel_fraction_max 1.000 _reflns_number_gt 3656 _reflns_number_total 6239 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution ? _refine_diff_density_max 0.379 _refine_diff_density_min -0.312 _refine_diff_density_rms 0.071 _refine_ls_abs_structure_details ; Flack x determined using 1100 quotients [(I+)-(I-)]/[(I+)+(I-)] (Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259). ; _refine_ls_abs_structure_Flack -0.3(10) _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 0.981 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 363 _refine_ls_number_reflns 6239 _refine_ls_number_restraints 230 _refine_ls_R_factor_all 0.1344 _refine_ls_R_factor_gt 0.0777 _refine_ls_restrained_S_all 0.977 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1325P)^2^] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1893 _refine_ls_wR_factor_ref 0.2266 _refine_special_details ; Refined as a 2-component twin. ; _olex2_refinement_description ; 1. Twinned data refinement Scales: 0.541(4) 0.459(4) 2. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All C(H,H,H) groups, All O(H) groups 3. Restrained distances O10-H10 0.83 with sigma of 0.01 O4-H4 = O1-H1 0.83 with sigma of 0.01 O6-H6 0.83 with sigma of 0.01 H11-O12 2.25 with sigma of 0.02 C17-H10 1.84 with sigma of 0.02 H12-C18 1.84 with sigma of 0.02 C16-H7 1.84 with sigma of 0.02 4. Restrained planarity O9, O10, C17, H10 with sigma of 0.001 O11, O12, C18, H11, H12 with sigma of 0.001 O7, O8, C16, H7 with sigma of 0.001 O3, O4, C8, H4, H3 with sigma of 0.001 5. Rigid body (RIGU) restrains All non-hydrogen atoms with sigma for 1-2 distances of 0.002 and sigma for 1-3 distances of 0.002 6. Others Fixed Sof: H3(0.5) H4(0.5) O1S(0.5) O2S(0.5) O3S(0.5) O4S(0.5) O5S(0.5) O6S(0.25) O7S(0.5) H11(0.5) H12(0.5) O8S(0.5) O9S(0.5) O10S(0.5) O11S(0.5) O12S(0.25) O13S(0.25) O14S(0.5) O15S(0.5) O16S(0.5) O17S(0.25) O18S(0.25) O19S(0.25) 7.a Aromatic/amide H refined with riding coordinates: C2(H2), C4(H4A), C6(H6A), C11(H11A), C13(H13), C15(H15) 7.b Idealised tetrahedral OH refined as rotating group: O3(H3), O7(H7), O11(H11), O12(H12) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary ? _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O -0.0224(4) 0.4998(5) 0.5061(4) 0.0291(16) Uani 1 1 d D U . . . O2 O -0.0254(4) 0.3635(5) 0.5022(5) 0.046(2) Uani 1 1 d . U . . . O3 O 0.2727(5) 0.3637(5) 0.5046(4) 0.0351(16) Uani 1 1 d . U . . . H3 H 0.3098 0.3430 0.5014 0.053 Uiso 0.5 1 calc GR . . . . O4 O 0.4073(5) 0.4996(5) 0.5049(4) 0.0357(19) Uani 1 1 d D U . . . O5 O 0.4072(4) 0.7957(4) 0.4994(4) 0.0238(13) Uani 1 1 d . U . . . O6 O 0.2718(5) 0.7927(5) 0.5008(5) 0.0390(19) Uani 1 1 d D U . . . C1 C 0.1212(5) 0.5025(7) 0.5063(5) 0.0232(16) Uani 1 1 d . U . . . C2 C 0.1687(7) 0.4533(6) 0.5073(4) 0.0236(16) Uani 1 1 d . U . . . H2 H 0.1356 0.3869 0.5088 0.028 Uiso 1 1 calc R . . . . C3 C 0.2666(7) 0.5034(6) 0.5062(4) 0.0210(16) Uani 1 1 d . U . . . C4 C 0.3157(6) 0.5972(7) 0.5049(4) 0.0218(16) Uani 1 1 d . U . . . H4A H 0.3821 0.6293 0.5052 0.026 Uiso 1 1 calc R . . . . C5 C 0.2669(6) 0.6478(6) 0.5029(4) 0.0203(16) Uani 1 1 d . U . . . C6 C 0.1700(7) 0.6010(7) 0.5019(5) 0.0256(19) Uani 1 1 d . U . . . H6A H 0.1372 0.6344 0.4984 0.031 Uiso 1 1 calc R . . . . C7 C 0.0165(6) 0.4512(8) 0.5051(4) 0.0234(16) Uani 1 1 d . U . . . C8 C 0.3178(8) 0.4505(7) 0.5070(4) 0.0274(19) Uani 1 1 d . U . . . C9 C 0.3184(7) 0.7525(5) 0.4999(4) 0.0186(14) Uani 1 1 d . U . . . H1 H -0.079(2) 0.479(6) 0.497(5) 0.028 Uiso 1 1 d DR . . . . H4 H 0.440(9) 0.475(10) 0.5017(9) 0.028 Uiso 0.5 1 d DR . . . . H6 H 0.310(5) 0.8489(19) 0.493(5) 0.028 Uiso 1 1 d DR . . . . O1S O 0.7593(19) 0.5898(19) 0.4658(14) 0.126(9) Uiso 0.5 1 d . U . A 1 O2S O 0.749(3) 0.623(3) 0.511(2) 0.177(12) Uiso 0.5 1 d . U . B 2 O3S O 0.777(2) 0.673(2) 0.5845(14) 0.151(9) Uiso 0.5 1 d . U . C 3 O4S O 0.811(3) 0.764(3) 0.706(2) 0.222(17) Uiso 0.5 1 d . U . D 4 O5S O 0.7661(18) 0.7225(19) 0.6400(15) 0.130(9) Uiso 0.5 1 d . U . E 5 O6S O 0.6762(14) 0.6762(14) 0.5000 0.068(6) Uiso 0.5 2 d S TU P F 6 O7S O 0.708(3) 0.649(3) 0.457(2) 0.181(13) Uiso 0.5 1 d . U . G 7 O7 O 0.4217(4) 0.3890(5) 0.6560(4) 0.0347(17) Uani 1 1 d . U . . . H7 H 0.4004 0.4256 0.6589 0.052 Uiso 1 1 calc DGR . . . . O8 O 0.5572(5) 0.5222(5) 0.6659(4) 0.0399(19) Uani 1 1 d . U . . . O9 O 0.8533(4) 0.5223(5) 0.6671(3) 0.0275(14) Uani 1 1 d . U . . . O10 O 0.8503(5) 0.3851(5) 0.6599(4) 0.0400(18) Uani 1 1 d D U . . . O11 O 0.5577(5) 0.0914(4) 0.6677(4) 0.0351(17) Uani 1 1 d . U . . . H11 H 0.5211 0.0334 0.6658 0.053 Uiso 0.5 1 calc DGR . . . . O12 O 0.4213(5) 0.0917(5) 0.6665(5) 0.051(2) Uani 1 1 d D U . . . H12 H 0.4002 0.0338 0.6648 0.076 Uiso 0.5 1 calc DGR . . . . C10 C 0.5602(7) 0.3823(7) 0.6597(5) 0.0275(18) Uani 1 1 d . U . . . C11 C 0.6586(7) 0.4313(6) 0.6585(4) 0.0231(15) Uani 1 1 d . U . . . H11A H 0.6922 0.4976 0.6565 0.028 Uiso 1 1 calc R . . . . C12 C 0.7067(6) 0.3811(7) 0.6603(4) 0.0203(15) Uani 1 1 d . U . . . C13 C 0.6587(7) 0.2860(7) 0.6623(4) 0.0224(17) Uani 1 1 d . U . . . H13 H 0.6923 0.2532 0.6610 0.027 Uiso 1 1 calc R . . . . C14 C 0.5614(7) 0.2358(6) 0.6660(4) 0.0235(15) Uani 1 1 d . U . . . C15 C 0.5123(6) 0.2840(6) 0.6622(4) 0.0193(16) Uani 1 1 d . U . . . H15 H 0.4459 0.2502 0.6612 0.023 Uiso 1 1 calc R . . . . C16 C 0.5117(7) 0.4361(7) 0.6594(4) 0.0228(17) Uani 1 1 d D U . . . C17 C 0.8106(6) 0.4326(7) 0.6629(4) 0.0223(17) Uani 1 1 d D U . . . C18 C 0.5102(7) 0.1340(6) 0.6684(4) 0.0260(17) Uani 1 1 d D U . . . H10 H 0.9084(12) 0.409(3) 0.6605(9) 0.03(3) Uiso 1 1 d D . . . . O8S O 0.931(3) 0.893(3) 0.514(3) 0.27(2) Uiso 0.5 1 d . U . H 8 O9S O 0.234(3) 0.121(3) 0.616(2) 0.226(18) Uiso 0.5 1 d . U . I 9 O10S O 0.731(4) 0.793(4) 0.700(2) 0.238(17) Uiso 0.5 1 d . U . J 10 O11S O 0.024(4) 0.726(4) 0.385(3) 0.29(2) Uiso 0.5 1 d . U . K 11 O12S O 0.012(7) 0.179(6) 0.381(4) 0.20(3) Uiso 0.25 1 d . U . L 12 O13S O 0.134(3) 0.165(3) 0.383(2) 0.087(11) Uiso 0.25 1 d . U . M 13 O14S O 0.152(3) 0.237(3) 0.314(2) 0.193(14) Uiso 0.5 1 d . U . N 14 O15S O 0.285(2) 0.225(2) 0.7875(17) 0.141(9) Uiso 0.5 1 d . U . O 15 O16S O 0.286(3) 0.231(3) 0.871(2) 0.195(14) Uiso 0.5 1 d . U . P 16 O17S O 0.142(3) 0.924(3) 0.580(2) 0.101(13) Uiso 0.25 1 d . U . Q 17 O18S O 0.111(5) 0.889(5) 0.498(4) 0.19(3) Uiso 0.25 1 d . U . R 18 O19S O 0.835(5) 0.826(5) 0.345(4) 0.19(3) Uiso 0.25 1 d . U . S 19 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.019(3) 0.033(4) 0.035(4) -0.001(3) -0.003(3) 0.013(3) O2 0.027(4) 0.025(3) 0.075(5) -0.004(3) 0.006(4) 0.005(3) O3 0.036(4) 0.030(3) 0.045(4) 0.001(3) 0.007(4) 0.020(2) O4 0.022(3) 0.037(4) 0.048(5) 0.004(4) 0.001(3) 0.015(3) O5 0.023(3) 0.017(3) 0.026(3) 0.000(3) 0.003(3) 0.006(2) O6 0.028(3) 0.021(3) 0.070(5) 0.010(4) 0.010(4) 0.015(3) C1 0.023(3) 0.024(3) 0.022(4) 0.005(3) 0.003(3) 0.012(3) C2 0.027(3) 0.026(3) 0.015(4) 0.005(3) 0.004(3) 0.011(3) C3 0.024(3) 0.021(3) 0.016(4) -0.001(3) 0.001(3) 0.010(3) C4 0.020(3) 0.021(3) 0.020(4) -0.001(3) -0.002(3) 0.007(3) C5 0.020(3) 0.019(3) 0.018(4) 0.001(2) 0.003(3) 0.007(2) C6 0.022(3) 0.024(3) 0.030(5) 0.003(3) 0.002(3) 0.011(3) C7 0.023(3) 0.026(3) 0.019(4) -0.001(3) 0.001(3) 0.010(3) C8 0.021(3) 0.026(3) 0.036(5) -0.003(3) 0.002(3) 0.012(3) C9 0.022(3) 0.021(3) 0.013(3) -0.002(2) 0.004(3) 0.011(3) O7 0.024(3) 0.035(3) 0.051(5) -0.009(3) -0.007(3) 0.019(2) O8 0.037(4) 0.027(3) 0.059(5) -0.004(3) -0.011(4) 0.019(3) O9 0.029(3) 0.023(3) 0.028(3) 0.001(3) -0.004(3) 0.011(2) O10 0.025(3) 0.035(4) 0.061(5) -0.003(4) -0.003(3) 0.016(3) O11 0.042(4) 0.025(3) 0.037(4) 0.002(3) -0.003(3) 0.016(3) O12 0.028(3) 0.025(3) 0.091(6) -0.004(4) 0.002(3) 0.007(2) C10 0.028(3) 0.027(3) 0.031(5) -0.001(3) -0.003(3) 0.016(3) C11 0.029(3) 0.023(3) 0.019(4) -0.001(3) -0.001(3) 0.014(3) C12 0.023(3) 0.023(3) 0.015(4) -0.004(3) -0.003(2) 0.012(2) C13 0.025(3) 0.025(3) 0.017(4) -0.004(3) -0.009(3) 0.013(3) C14 0.022(3) 0.028(3) 0.018(3) 0.000(2) -0.007(3) 0.011(3) C15 0.021(3) 0.027(3) 0.009(3) 0.000(3) -0.003(3) 0.011(3) C16 0.025(3) 0.023(3) 0.021(4) -0.002(3) -0.006(3) 0.013(2) C17 0.021(3) 0.020(3) 0.022(4) -0.001(3) -0.001(3) 0.008(3) C18 0.026(3) 0.028(3) 0.021(4) 0.001(3) 0.000(3) 0.012(3) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C7 1.254(12) . ? O1 H1 0.833(14) . ? O2 C7 1.257(13) . ? O3 H3 0.8400 . ? O3 C8 1.244(12) . ? O4 C8 1.284(13) . ? O4 H4 0.832(14) . ? O5 C9 1.271(11) . ? O6 C9 1.244(12) . ? O6 H6 0.834(14) . ? C1 C2 1.384(14) . ? C1 C6 1.412(14) . ? C1 C7 1.499(11) . ? C2 H2 0.9500 . ? C2 C3 1.401(13) . ? C3 C4 1.343(13) . ? C3 C8 1.489(12) . ? C4 H4A 0.9500 . ? C4 C5 1.424(13) . ? C5 C6 1.387(12) . ? C5 C9 1.500(10) . ? C6 H6A 0.9500 . ? O7 H7 0.8400 . ? O7 C16 1.290(11) . ? O8 C16 1.239(12) . ? O9 C17 1.286(11) . ? O10 C17 1.252(12) . ? O10 H10 0.836(14) . ? O11 H11 0.8400 . ? O11 C18 1.290(13) . ? O12 H12 0.8400 . ? O12 C18 1.274(12) . ? C10 C11 1.407(13) . ? C10 C15 1.408(13) . ? C10 C16 1.465(11) . ? C11 H11A 0.9500 . ? C11 C12 1.407(12) . ? C12 C13 1.362(12) . ? C12 C17 1.487(11) . ? C13 H13 0.9500 . ? C13 C14 1.395(13) . ? C14 C15 1.394(13) . ? C14 C18 1.458(11) . ? C15 H15 0.9500 . ? O8S O8S 1.24(9) 6_556 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C7 O1 H1 124(7) . . ? C8 O3 H3 109.5 . . ? C8 O4 H4 121(10) . . ? C9 O6 H6 106(6) . . ? C2 C1 C6 121.0(8) . . ? C2 C1 C7 120.1(10) . . ? C6 C1 C7 118.9(10) . . ? C1 C2 H2 120.7 . . ? C1 C2 C3 118.6(8) . . ? C3 C2 H2 120.7 . . ? C2 C3 C8 118.7(9) . . ? C4 C3 C2 122.3(8) . . ? C4 C3 C8 119.0(9) . . ? C3 C4 H4A 120.5 . . ? C3 C4 C5 119.1(8) . . ? C5 C4 H4A 120.5 . . ? C4 C5 C9 121.1(9) . . ? C6 C5 C4 120.5(8) . . ? C6 C5 C9 118.3(8) . . ? C1 C6 H6A 120.8 . . ? C5 C6 C1 118.4(9) . . ? C5 C6 H6A 120.8 . . ? O1 C7 O2 125.1(7) . . ? O1 C7 C1 117.0(10) . . ? O2 C7 C1 117.9(10) . . ? O3 C8 O4 124.3(8) . . ? O3 C8 C3 119.2(10) . . ? O4 C8 C3 116.3(9) . . ? O5 C9 C5 118.6(9) . . ? O6 C9 O5 123.4(7) . . ? O6 C9 C5 118.0(9) . . ? C16 O7 H7 109.5 . . ? C17 O10 H10 123(3) . . ? C18 O11 H11 109.5 . . ? C18 O12 H12 109.5 . . ? C11 C10 C15 119.0(8) . . ? C11 C10 C16 118.4(9) . . ? C15 C10 C16 122.5(9) . . ? C10 C11 H11A 120.3 . . ? C12 C11 C10 119.4(7) . . ? C12 C11 H11A 120.3 . . ? C11 C12 C17 119.6(9) . . ? C13 C12 C11 120.4(9) . . ? C13 C12 C17 119.9(8) . . ? C12 C13 H13 119.3 . . ? C12 C13 C14 121.3(9) . . ? C14 C13 H13 119.3 . . ? C13 C14 C18 121.3(10) . . ? C15 C14 C13 119.0(8) . . ? C15 C14 C18 119.6(10) . . ? C10 C15 H15 119.7 . . ? C14 C15 C10 120.6(8) . . ? C14 C15 H15 119.7 . . ? O7 C16 C10 116.7(9) . . ? O8 C16 O7 123.6(8) . . ? O8 C16 C10 119.6(9) . . ? O9 C17 C12 118.3(9) . . ? O10 C17 O9 124.6(7) . . ? O10 C17 C12 117.2(8) . . ? O11 C18 C14 118.0(10) . . ? O12 C18 O11 123.4(7) . . ? O12 C18 C14 118.4(10) . . ? _shelx_res_file ; tma_8-32_butanol_mesitylene_100k.res created by SHELXL-2014/7 TITL trig_a.res in P3(2)21 REM Old TITL Trig in P-3 REM SHELXT solution in P3(2)21 REM R1 0.406, Rweak 0.031, Alpha 0.371, Orientation as input REM Flack x = 0.466 ( 0.070 ) from Parsons' quotients REM Formula found by SHELXT: C36 Cl CELL 0.71073 16.523 16.523 19.4003 90 90 120 ZERR 6 0.0016 0.0016 0.002 0 0 0 LATT -1 SYMM -Y,+X-Y,0.667+Z SYMM +Y-X,-X,0.333+Z SYMM -Y+X,-Y,0.333-Z SYMM -X,-X+Y,0.667-Z SYMM +Y,+X,-Z SFAC C H O UNIT 108 72 120 DFIX 0.83 0.01 O10 H10 DFIX 0.83 0.01 O4 H4 O1 H1 DFIX 0.83 0.01 O6 H6 DANG 2.25 0.02 H11 O12 DANG 1.84 0.02 C17 H10 DANG 1.84 0.02 H12 C18 DANG 1.84 0.02 C16 H7 FLAT 0.001 O9 O10 C17 H10 FLAT 0.001 O11 O12 C18 H11 H12 FLAT 0.001 O7 O8 C16 H7 FLAT 0.001 O3 O4 C8 H4 H3 RIGU 0.002 0.002 L.S. 99 PLAN 20 SIZE 0.134 0.063 0.039 TEMP -173.15 BOND $H list 4 fmap 2 acta TWIN -1 0 0 0 -1 0 0 0 1 2 OMIT 0 1 0 OMIT 0 1 1 REM REM REM WGHT 0.132500 BASF 0.45906 FVAR 0.33006 O1 3 -0.022366 0.499804 0.506142 11.00000 0.01948 0.03320 = 0.03507 -0.00084 -0.00319 0.01347 O2 3 -0.025416 0.363513 0.502184 11.00000 0.02716 0.02460 = 0.07460 -0.00352 0.00564 0.00503 O3 3 0.272685 0.363669 0.504570 11.00000 0.03552 0.02992 = 0.04501 0.00138 0.00675 0.02011 AFIX 147 H3 2 0.309815 0.343036 0.501371 10.50000 -1.50000 AFIX 0 O4 3 0.407301 0.499587 0.504877 11.00000 0.02203 0.03708 = 0.04820 0.00446 0.00054 0.01494 O5 3 0.407207 0.795737 0.499419 11.00000 0.02328 0.01691 = 0.02600 0.00011 0.00283 0.00607 O6 3 0.271780 0.792699 0.500799 11.00000 0.02845 0.02146 = 0.06991 0.00976 0.01011 0.01468 C1 1 0.121246 0.502533 0.506308 11.00000 0.02297 0.02405 = 0.02230 0.00459 0.00276 0.01155 C2 1 0.168717 0.453282 0.507346 11.00000 0.02693 0.02585 = 0.01541 0.00452 0.00442 0.01114 AFIX 43 H2 2 0.135622 0.386922 0.508807 11.00000 -1.20000 AFIX 0 C3 1 0.266595 0.503371 0.506198 11.00000 0.02411 0.02127 = 0.01593 -0.00144 0.00134 0.01011 C4 1 0.315713 0.597189 0.504879 11.00000 0.02038 0.02090 = 0.01990 -0.00112 -0.00164 0.00717 AFIX 43 H4A 2 0.382090 0.629307 0.505238 11.00000 -1.20000 AFIX 0 C5 1 0.266868 0.647814 0.502937 11.00000 0.02044 0.01852 = 0.01810 0.00110 0.00270 0.00690 C6 1 0.169965 0.601015 0.501918 11.00000 0.02182 0.02439 = 0.03021 0.00326 0.00180 0.01127 AFIX 43 H6A 2 0.137165 0.634428 0.498353 11.00000 -1.20000 AFIX 0 C7 1 0.016532 0.451222 0.505141 11.00000 0.02281 0.02575 = 0.01853 -0.00119 0.00144 0.00987 C8 1 0.317778 0.450529 0.507008 11.00000 0.02080 0.02570 = 0.03581 -0.00262 0.00150 0.01161 C9 1 0.318430 0.752531 0.499948 11.00000 0.02228 0.02088 = 0.01270 -0.00189 0.00351 0.01073 H1 2 -0.078667 0.479256 0.497320 11.00000 -1.50000 H4 2 0.440163 0.474675 0.501671 10.50000 -1.50000 H6 2 0.309556 0.848914 0.492910 11.00000 -1.50000 PART 1 O1S 3 0.759316 0.589796 0.465785 10.50000 0.12635 PART 0 PART 2 O2S 3 0.749311 0.622565 0.510914 10.50000 0.17662 PART 0 PART 3 O3S 3 0.776711 0.672626 0.584534 10.50000 0.15073 PART 0 PART 4 O4S 3 0.810600 0.764064 0.706423 10.50000 0.22241 PART 0 PART 5 O5S 3 0.766140 0.722470 0.639997 10.50000 0.12956 PART 0 PART 6 O6S 3 0.676157 0.676157 0.500000 10.25000 0.06828 PART 0 PART 7 O7S 3 0.707576 0.648552 0.456852 10.50000 0.18136 PART 0 O7 3 0.421720 0.388980 0.655999 11.00000 0.02409 0.03459 = 0.05114 -0.00926 -0.00670 0.01903 AFIX 147 H7 2 0.400403 0.425570 0.658868 11.00000 -1.50000 AFIX 0 O8 3 0.557235 0.522230 0.665861 11.00000 0.03724 0.02718 = 0.05867 -0.00445 -0.01064 0.01864 O9 3 0.853343 0.522300 0.667135 11.00000 0.02874 0.02336 = 0.02798 0.00078 -0.00399 0.01123 O10 3 0.850286 0.385052 0.659918 11.00000 0.02488 0.03511 = 0.06118 -0.00317 -0.00279 0.01595 O11 3 0.557743 0.091384 0.667661 11.00000 0.04217 0.02482 = 0.03674 0.00186 -0.00263 0.01560 AFIX 147 H11 2 0.521052 0.033413 0.665825 10.50000 -1.50000 AFIX 0 O12 3 0.421275 0.091698 0.666540 11.00000 0.02771 0.02482 = 0.09077 -0.00425 0.00154 0.00685 AFIX 147 H12 2 0.400180 0.033751 0.664834 10.50000 -1.50000 AFIX 0 C10 1 0.560249 0.382327 0.659734 11.00000 0.02755 0.02714 = 0.03138 -0.00063 -0.00329 0.01626 C11 1 0.658581 0.431294 0.658541 11.00000 0.02872 0.02316 = 0.01881 -0.00147 -0.00112 0.01407 AFIX 43 H11A 2 0.692167 0.497627 0.656549 11.00000 -1.20000 AFIX 0 C12 1 0.706695 0.381146 0.660323 11.00000 0.02327 0.02338 = 0.01454 -0.00395 -0.00253 0.01177 C13 1 0.658746 0.286015 0.662258 11.00000 0.02499 0.02547 = 0.01711 -0.00411 -0.00863 0.01297 AFIX 43 H13 2 0.692268 0.253169 0.661006 11.00000 -1.20000 AFIX 0 C14 1 0.561420 0.235818 0.666039 11.00000 0.02219 0.02836 = 0.01789 0.00008 -0.00690 0.01110 C15 1 0.512322 0.283982 0.662196 11.00000 0.02074 0.02664 = 0.00904 -0.00005 -0.00277 0.01074 AFIX 43 H15 2 0.445948 0.250172 0.661230 11.00000 -1.20000 AFIX 0 C16 1 0.511700 0.436139 0.659374 11.00000 0.02510 0.02268 = 0.02148 -0.00214 -0.00623 0.01265 C17 1 0.810554 0.432634 0.662881 11.00000 0.02096 0.02025 = 0.02247 -0.00101 -0.00095 0.00797 C18 1 0.510233 0.133958 0.668393 11.00000 0.02637 0.02764 = 0.02143 0.00135 -0.00025 0.01154 H10 2 0.908373 0.408929 0.660523 11.00000 0.02937 PART 8 O8S 3 0.931324 0.892726 0.514487 10.50000 0.27086 PART 0 PART 9 O9S 3 0.234127 0.121184 0.615810 10.50000 0.22637 PART 0 PART 10 O10S 3 0.730726 0.792610 0.699501 10.50000 0.23809 PART 0 PART 11 O11S 3 0.024484 0.725755 0.385041 10.50000 0.28716 PART 0 PART 12 O12S 3 0.012093 0.178675 0.380776 10.25000 0.19937 PART 0 PART 13 O13S 3 0.134080 0.164940 0.382618 10.25000 0.08688 PART 0 PART 14 O14S 3 0.151786 0.236602 0.313851 10.50000 0.19292 PART 0 PART 15 O15S 3 0.284519 0.225302 0.787501 10.50000 0.14065 PART 0 PART 16 O16S 3 0.285687 0.231179 0.870527 10.50000 0.19497 PART 0 PART 17 O17S 3 0.141790 0.924349 0.579884 10.25000 0.10127 PART 0 PART 18 O18S 3 0.110738 0.888721 0.497991 10.25000 0.18789 PART 0 PART 19 O19S 3 0.835189 0.826192 0.345262 10.25000 0.19080 HKLF 4 REM trig_a.res in P3(2)21 REM R1 = 0.0777 for 3656 Fo > 4sig(Fo) and 0.1344 for all 6239 data REM 363 parameters refined using 230 restraints END WGHT 0.1302 0.0000 REM Highest difference peak 0.379, deepest hole -0.312, 1-sigma level 0.071 Q1 1 0.6966 0.7526 0.6133 11.00000 0.05 0.38 Q2 1 0.8961 0.8964 0.2771 11.00000 0.05 0.31 Q3 1 0.1114 0.1496 0.4469 11.00000 0.05 0.31 Q4 1 0.0586 0.2000 0.4326 11.00000 0.05 0.27 Q5 1 0.1237 0.8719 0.4485 11.00000 0.05 0.27 Q6 1 0.0992 0.7087 0.3363 11.00000 0.05 0.26 Q7 1 0.7085 0.6466 0.5003 11.00000 0.05 0.25 Q8 1 0.8799 0.7703 0.6822 11.00000 0.05 0.25 Q9 1 0.8033 0.7170 0.6830 11.00000 0.05 0.25 Q10 1 0.8238 0.2774 0.6806 11.00000 0.05 0.24 Q11 1 0.8419 0.6497 0.4809 11.00000 0.05 0.24 Q12 1 1.0103 0.9978 0.5748 11.00000 0.05 0.24 Q13 1 0.7882 0.6754 0.7535 11.00000 0.05 0.24 Q14 1 1.0000 0.8803 0.3333 10.50000 0.05 0.24 Q15 1 0.0939 0.3141 0.5013 11.00000 0.05 0.24 Q16 1 0.1160 0.0635 0.3897 11.00000 0.05 0.23 Q17 1 0.1324 0.9427 0.5340 11.00000 0.05 0.23 Q18 1 0.1800 1.0099 0.5293 11.00000 0.05 0.23 Q19 1 0.1468 0.2591 0.4883 11.00000 0.05 0.23 Q20 1 0.7514 0.6604 0.5452 11.00000 0.05 0.23 ; _shelx_res_checksum 92153 _olex2_submission_special_instructions 'No special instructions were received' loop_ _twin_individual_id _twin_individual_mass_fraction_refined 1 0.541(4) 2 0.459(4) ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_ADTA_2-35_THF-1-3-dimethoxybenzene_publ _database_code_depnum_ccdc_archive 'CCDC 1915312' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2019-01-07 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety '(C14 H20 O8), 17.5(O)' _chemical_formula_sum 'C14 H20 O25.50' _chemical_formula_weight 596.30 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system tetragonal _space_group_IT_number 134 _space_group_name_H-M_alt 'P 42/n n m' _space_group_name_Hall '-P 4ac 2bc' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x+1/2, -y+1/2, z' '-y+1/2, x, z+1/2' 'y, -x+1/2, z+1/2' '-x+1/2, y, -z+1/2' 'x, -y+1/2, -z+1/2' 'y, x, -z' '-y+1/2, -x+1/2, -z' '-x, -y, -z' 'x-1/2, y-1/2, -z' 'y-1/2, -x, -z-1/2' '-y, x-1/2, -z-1/2' 'x-1/2, -y, z-1/2' '-x, y-1/2, z-1/2' '-y, -x, z' 'y-1/2, x-1/2, z' _cell_length_a 11.4331(8) _cell_length_b 11.4331(8) _cell_length_c 11.4312(8) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 90 _cell_volume 1494.2(2) _cell_formula_units_Z 2 _cell_measurement_reflns_used 5245 _cell_measurement_temperature 200 _cell_measurement_theta_max 26.358 _cell_measurement_theta_min 2.519 _shelx_estimated_absorpt_T_max ? _shelx_estimated_absorpt_T_min ? _exptl_absorpt_coefficient_mu 0.134 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4951 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. Estimated minimum and maximum transmission: 0.4951 0.7454 Additional spherical absorption correction applied with mu*r = 0.2000 Lambda/2 correction factor = 0.00150 ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.325 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description prism _exptl_crystal_F_000 616 _exptl_crystal_size_max 0.135 _exptl_crystal_size_mid 0.11 _exptl_crystal_size_min 0.11 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0453 _diffrn_reflns_av_unetI/netI 0.0193 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 1.000 _diffrn_reflns_limit_h_max 14 _diffrn_reflns_limit_h_min -14 _diffrn_reflns_limit_k_max 14 _diffrn_reflns_limit_k_min -14 _diffrn_reflns_limit_l_max 14 _diffrn_reflns_limit_l_min -10 _diffrn_reflns_number 17215 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 1.000 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.360 _diffrn_reflns_theta_min 1.781 _diffrn_ambient_temperature 200 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 1.000 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 682 _reflns_number_total 829 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection 'CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011)' _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'ShelXT (Sheldrick, 2015)' _refine_diff_density_max 0.177 _refine_diff_density_min -0.398 _refine_diff_density_rms 0.084 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.142 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 98 _refine_ls_number_reflns 829 _refine_ls_number_restraints 6 _refine_ls_R_factor_all 0.0860 _refine_ls_R_factor_gt 0.0760 _refine_ls_restrained_S_all 1.148 _refine_ls_shift/su_max 0.001 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1228P)^2^+0.2939P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1852 _refine_ls_wR_factor_ref 0.2009 _refine_special_details ; Refined as a 2-component twin with the TWINLAW TWIN -1 0 0 0 0 1 0 1 0 2 ; _olex2_refinement_description ; 1. Twinned data refinement Scales: 0.532(12) 0.468(12) 2. Fixed Uiso At 1.2 times of: All C(H,H) groups At 1.5 times of: All O(H) groups 3. Uiso/Uaniso restraints and constraints Uanis(O1) \\sim Ueq: with sigma of 0.01 and sigma for terminal atoms of 0.02 4. Others Fixed Sof: O1(0.16667) H1(0.16667) O2(0.33333) H2(0.33333) O3(0.33333) H3(0.33333) O4(0.16667) H4(0.16667) H1A(0.5) H1B(0.5) H3B(0.25) H3A(0.25) O1S(0.125) O3S(0.125) O4S(0.25) O6S(0.125) O7S(0.0625) O5S(0.125) O9S(0.25) O10S(0.25) O11S(0.25) O12S(0.125) O13S(0.25) O8S(0.125) O2S(0.125) Fixed X: H1(0.443999) H2(0.402549) H3(0.44502) H4(0.516469) Fixed Y: H1(0.556009) H2(0.497789) H3(0.45899) H4(0.499439) Fixed Z: H1(0.45728) H2(0.486819) H3(0.55843) H4(0.60143) 5.a Secondary CH2 refined with riding coordinates: C1(H1A,H1B), C3(H3B,H3A) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.3989(7) 0.6011(7) 0.4880(6) 0.066(4) Uani 0.3333 2 d S TU P A 1 H1 H 0.4440 0.5560 0.4573 0.099 Uiso 0.3333 2 d RS T P B 1 O2 O 0.3518(8) 0.5322(14) 0.5257(13) 0.088(3) Uani 0.3333 1 d . . . A 3 H2 H 0.4025 0.4978 0.4868 0.132 Uiso 0.3333 1 d R . . C 3 O3 O 0.3992(12) 0.4883(7) 0.6025(10) 0.073(3) Uani 0.3333 1 d . . . A 2 H3 H 0.4450 0.4590 0.5584 0.109 Uiso 0.3333 1 d R . . D 2 O4 O 0.4691(6) 0.5309(6) 0.6451(8) 0.079(6) Uani 0.3333 2 d S T P A 1 H4 H 0.5165 0.4994 0.6014 0.118 Uiso 0.1667 1 d R . . E 1 C1 C 0.4062(3) 0.7500 0.7500 0.0308(9) Uani 1 2 d S T P . . H1A H 0.4568 0.7003 0.7996 0.037 Uiso 0.5 1 calc R . . . . H1B H 0.4568 0.7996 0.7004 0.037 Uiso 0.5 1 calc R . . . . C2 C 0.3275(2) 0.6725(2) 0.6725(2) 0.0298(8) Uani 1 2 d S T P A . C3 C 0.2500 0.7500 0.5951(3) 0.0323(13) Uani 1 4 d S T P . . H3B H 0.2004 0.7004 0.5444 0.039 Uiso 0.5 2 calc RS T P . . H3A H 0.2996 0.7996 0.5444 0.039 Uiso 0.5 2 calc RS T P . . C4 C 0.4047(2) 0.5953(2) 0.5966(3) 0.0354(9) Uani 1 2 d S T P . . O1S O 0.647(5) 0.787(5) 0.422(4) 0.139(14) Uiso 0.125 1 d . . . F 1 O3S O 0.517(7) 0.806(5) 0.329(5) 0.166(15) Uiso 0.125 1 d . . . G 3 O4S O 0.463(2) 0.887(2) 0.3526(18) 0.132(5) Uiso 0.25 1 d . . . H 4 O6S O 0.630(3) 0.370(3) 0.787(3) 0.173(13) Uiso 0.25 2 d S T P I 6 O7S O 0.319(7) 0.681(7) 0.263(12) 0.23(4) Uiso 0.125 2 d S T P J 7 O5S O 0.5373(13) 0.4627(13) 0.9147(16) 0.086(5) Uiso 0.25 2 d S T P K 5 O9S O 0.5170(13) 0.9573(13) 0.4718(11) 0.096(4) Uiso 0.25 1 d . . . L 9 O10S O 0.5216(14) 0.8957(13) 0.4242(12) 0.089(4) Uiso 0.25 1 d . . . M 10 O11S O 0.580(4) 0.834(4) 0.414(3) 0.191(11) Uiso 0.25 1 d . . . N 11 O12S O 0.708(4) 0.792(4) 0.5000 0.26(3) Uiso 0.25 2 d S T P O 12 O13S O 0.6051(16) 0.8949(16) 0.5000 0.188(7) Uiso 0.5 2 d S T P P 13 O8S O 0.422(6) 0.774(10) 0.272(9) 0.22(3) Uiso 0.125 1 d . . . Q 8 O2S O 0.759(10) 0.613(6) 0.692(5) 0.23(3) Uiso 0.125 1 d . . . R 2 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.093(6) 0.093(6) 0.012(3) -0.007(2) 0.007(2) 0.042(8) O2 0.052(6) 0.118(10) 0.094(7) -0.082(6) -0.002(4) 0.003(5) O3 0.104(8) 0.046(6) 0.068(6) -0.009(3) 0.054(4) -0.005(4) O4 0.107(9) 0.107(9) 0.022(4) -0.006(2) 0.006(2) 0.075(11) C1 0.028(2) 0.039(2) 0.0252(19) 0.0001(8) 0.000 0.000 C2 0.0339(18) 0.0339(18) 0.0217(18) -0.0024(5) 0.0024(5) -0.0017(13) C3 0.037(2) 0.037(2) 0.022(2) 0.000 0.000 0.0058(18) C4 0.041(2) 0.041(2) 0.025(2) -0.0002(6) 0.0002(6) 0.0041(15) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 H1 0.809(10) . ? O1 C4 1.245(8) . ? O2 H2 0.830(8) . ? O2 C4 1.242(7) . ? O3 H3 0.800(6) . ? O3 C4 1.228(8) . ? O4 H4 0.821(9) . ? O4 C4 1.180(12) . ? C1 H1A 0.9900 . ? C1 H1B 0.9900 . ? C1 C2 1.542(2) . ? C1 C2 1.542(2) 12_667 ? C2 C1 1.542(2) 11_567 ? C2 C3 1.533(5) . ? C2 C4 1.520(3) . ? C3 C2 1.533(5) 2_565 ? C3 H3B 0.9900 . ? C3 H3A 0.9900 . ? C4 O2 1.242(7) 15_665 ? C4 O3 1.228(8) 15_665 ? O4S O4S 1.22(4) 16_565 ? O7S O7S 1.60(14) 11_566 ? O7S O7S 1.60(14) 12_666 ? O9S O9S 0.77(3) 8_666 ? O9S O9S 1.233(18) 9_676 ? O9S O9S 0.97(3) 16_565 ? O12S O12S 1.35(12) 2_665 ? O8S O8S 0.74(19) 6_565 ? O2S O2S 1.35(13) 5_656 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C4 O1 H1 111.5(10) . . ? C4 O2 H2 106.6(8) . . ? C4 O3 H3 110.5(7) . . ? C4 O4 H4 113.6(9) . . ? H1A C1 H1B 108.3 . . ? C2 C1 H1A 110.0 12_667 . ? C2 C1 H1A 110.0 . . ? C2 C1 H1B 110.0 12_667 . ? C2 C1 H1B 110.0 . . ? C2 C1 C2 108.6(3) 12_667 . ? C1 C2 C1 109.9(2) . 11_567 ? C3 C2 C1 109.66(17) . 11_567 ? C3 C2 C1 109.66(17) . . ? C4 C2 C1 108.83(19) . . ? C4 C2 C1 108.83(19) . 11_567 ? C4 C2 C3 110.0(3) . . ? C2 C3 C2 109.6(3) . 2_565 ? C2 C3 H3B 109.8 2_565 . ? C2 C3 H3B 109.8 . . ? C2 C3 H3A 109.8 . . ? C2 C3 H3A 109.8 2_565 . ? H3B C3 H3A 108.2 . . ? O1 C4 C2 120.5(6) . . ? O2 C4 O2 98.0(17) 15_665 . ? O2 C4 C2 115.3(5) . . ? O2 C4 C2 115.3(5) 15_665 . ? O3 C4 O3 95.7(13) 15_665 . ? O3 C4 C2 121.2(3) . . ? O3 C4 C2 121.2(3) 15_665 . ? O4 C4 O1 122.3(7) . . ? O4 C4 C2 117.2(5) . . ? O7S O7S O7S 88(4) 11_566 12_666 ? O9S O9S O9S 89.997(3) 8_666 16_565 ? O9S O9S O9S 38.4(15) 16_565 9_676 ? O9S O9S O9S 51.6(15) 8_666 9_676 ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O1 H1 O4 0.809(10) 1.830(9) 2.622(13) 165.9(7) 7_556 O2 H2 O2 0.830(8) 2.237(12) 2.98(2) 148.3(12) 7_556 O3 H3 O3 0.800(6) 2.024(7) 2.750(14) 150.8(10) 7_556 O4 H4 O1 0.821(9) 1.817(9) 2.622(13) 166.4(2) 7_556 _shelx_res_file ; pc_8_235_200k_tetp.res created by SHELXL-2014/7 TITL pc_8_235_200k_tetp_a.res in P4(2)/nnm REM Old TITL PC_8_235_200K_TetP in P4(2)/nnm REM SHELXT solution in P4(2)/nnm REM R1 0.457, Rweak 0.034, Alpha 0.073, Orientation as input REM Formula found by SHELXT: C7 CELL 0.71073 11.4331 11.4331 11.4312 90 90 90 ZERR 2 0.0008 0.0008 0.0008 0 0 0 LATT 1 SYMM 0.5-X,0.5-Y,+Z SYMM 0.5-Y,+X,0.5+Z SYMM +Y,0.5-X,0.5+Z SYMM 0.5-X,+Y,0.5-Z SYMM +X,0.5-Y,0.5-Z SYMM +Y,+X,-Z SYMM 0.5-Y,0.5-X,-Z SFAC C H O UNIT 28 40 51 EQIV $1 1-Y,1-X,+Z EQIV $2 +Y,+X,1-Z ISOR 0.01 0.02 O1 L.S. 10 PLAN 20 TEMP -73.15 HTAB O1 O4_$2 HTAB O2 O2_$2 HTAB O3 O3_$2 HTAB O4 O1_$2 FREE O3 O3_$1 BOND $H list 4 fmap 2 53 acta TWIN -1 0 0 0 0 1 0 1 0 2 REM REM REM WGHT 0.122800 0.293900 BASF 0.46779 FVAR 1.13976 PART 1 O1 3 0.398908 0.601092 0.488017 10.16667 0.09307 0.09307 = 0.01234 -0.00712 0.00712 0.04164 H1 2 10.443999 10.556009 10.457280 10.16667 -1.50000 PART 0 PART 3 O2 3 0.351811 0.532176 0.525737 10.33333 0.05248 0.11846 = 0.09370 -0.08245 -0.00220 0.00264 H2 2 10.402549 10.497789 10.486819 10.33333 -1.50000 PART 0 PART 2 O3 3 0.399168 0.488276 0.602470 10.33333 0.10432 0.04643 = 0.06795 -0.00921 0.05433 -0.00542 H3 2 10.445020 10.458990 10.558430 10.33333 -1.50000 PART 0 PART 1 O4 3 0.469050 0.530950 0.645140 10.16667 0.10660 0.10660 = 0.02250 -0.00594 0.00594 0.07471 H4 2 10.516469 10.499439 10.601430 10.16667 -1.50000 PART 0 C1 1 0.406156 0.750000 0.750000 10.50000 0.02800 0.03908 = 0.02522 0.00013 0.00000 0.00000 AFIX 23 H1A 2 0.456841 0.700350 0.799645 10.50000 -1.20000 H1B 2 0.456843 0.799650 0.700356 10.50000 -1.20000 AFIX 0 C2 1 0.327479 0.672521 0.672486 10.50000 0.03393 0.03393 = 0.02169 -0.00241 0.00241 -0.00175 C3 1 0.250000 0.750000 0.595120 10.25000 0.03741 0.03741 = 0.02194 0.00000 0.00000 0.00580 AFIX 23 H3B 2 0.200394 0.700395 0.544352 10.25000 -1.20000 H3A 2 0.299605 0.799606 0.544352 10.25000 -1.20000 AFIX 0 C4 1 0.404650 0.595350 0.596620 10.50000 0.04055 0.04055 = 0.02508 -0.00015 0.00015 0.00413 PART 1 O1S 3 0.647261 0.786513 0.422333 10.12500 0.13887 PART 0 PART 3 O3S 3 0.516990 0.805944 0.328985 10.12500 0.16625 PART 0 PART 4 O4S 3 0.463224 0.887471 0.352628 10.25000 0.13176 PART 0 PART 6 O6S 3 0.629946 0.370054 0.787388 10.12500 0.17301 PART 0 PART 7 O7S 3 0.318935 0.681065 0.262990 10.06250 0.23238 PART 0 PART 5 O5S 3 0.537334 0.462666 0.914687 10.12500 0.08568 PART 0 PART 9 O9S 3 0.517038 0.957291 0.471848 10.25000 0.09640 PART 0 PART 10 O10S 3 0.521624 0.895687 0.424198 10.25000 0.08898 PART 0 PART 11 O11S 3 0.580121 0.834152 0.414071 10.25000 0.19127 PART 0 PART 12 O12S 3 0.708380 0.791620 0.500000 10.12500 0.25771 PART 0 PART 13 O13S 3 0.605133 0.894867 0.500000 10.25000 0.18827 PART 0 PART 8 O8S 3 0.421938 0.773877 0.271902 10.12500 0.22473 PART 0 PART 2 O2S 3 0.758613 0.613008 0.691524 10.12500 0.22880 HKLF 4 REM pc_8_235_200k_tetp_a.res in P4(2)/nnm REM R1 = 0.0760 for 682 Fo > 4sig(Fo) and 0.0860 for all 829 data REM 98 parameters refined using 6 restraints END WGHT 0.1214 0.3053 REM Highest difference peak 0.177, deepest hole -0.398, 1-sigma level 0.084 Q1 1 0.8205 0.5790 0.7493 11.00000 0.05 0.18 Q2 1 0.7500 0.6610 0.7500 10.50000 0.05 0.17 Q3 1 0.8466 0.6106 0.7541 11.00000 0.05 0.17 Q4 1 0.8061 0.7271 0.7311 11.00000 0.05 0.16 Q5 1 0.8154 0.7289 0.7392 11.00000 0.05 0.16 Q6 1 0.7500 0.7500 0.6651 10.50000 0.05 0.16 Q7 1 0.3760 0.8760 0.6252 10.50000 0.05 0.15 Q8 1 0.8701 0.7500 0.7500 10.50000 0.05 0.14 Q9 1 0.2965 0.6394 0.6995 11.00000 0.05 0.13 Q10 1 0.5852 0.7983 0.7600 11.00000 0.05 0.13 Q11 1 0.5252 0.7434 0.7869 11.00000 0.05 0.12 Q12 1 0.3568 0.6432 0.6549 10.50000 0.05 0.12 Q13 1 0.8661 0.6989 0.6838 11.00000 0.05 0.12 Q14 1 0.5021 0.8229 0.1969 11.00000 0.05 0.12 Q15 1 0.5193 0.7500 0.2500 10.50000 0.05 0.12 Q16 1 0.7949 0.6335 0.6600 11.00000 0.05 0.12 Q17 1 0.4384 0.4593 0.7457 11.00000 0.05 0.12 Q18 1 0.5163 0.9085 0.2552 11.00000 0.05 0.12 Q19 1 0.3016 0.6625 0.6825 11.00000 0.05 0.11 Q20 1 0.7585 0.5858 0.6685 11.00000 0.05 0.11 ; _shelx_res_checksum 73584 _olex2_submission_special_instructions 'No special instructions were received' loop_ _twin_individual_id _twin_individual_mass_fraction_refined 1 0.532(12) 2 0.468(12) ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_TMA_2-33_THF-butylbenzene_publ _database_code_depnum_ccdc_archive 'CCDC 1915315' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; # start Validation Reply Form _vrf_PLAT043_TMA_2-33_THF-bultybenzene_publ ; PROBLEM: Calculated and Reported Mol. Weight Differ by .. 4.03 Check RESPONSE: Disordered electron density was tentatively modelled as disordered H2O, these were refined without H-atoms, however, H-atoms for these were still included in the unit cell atom count. ; _vrf_PLAT601_TMA_2-33_THF-bultybenzene_publ ; PROBLEM: Structure Contains Solvent Accessible VOIDS of . 150 Ang**3 RESPONSE: These are likely to contain disordered solvent molecules which could not be resolved during refinement. ; # end Validation Reply Form _audit_creation_date 2018-05-21 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.18 svn.r3508 for OlexSys, GUI svn.r5497) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety 'C9 H6 O6, 2(H2 O)' _chemical_formula_sum 'C9 H10 O8' _chemical_formula_weight 246.17 _chemical_absolute_configuration ? _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system trigonal _space_group_IT_number 152 _space_group_name_H-M_alt 'P 31 2 1' _space_group_name_Hall 'P 31 2"' loop_ _space_group_symop_operation_xyz 'x, y, z' '-y, x-y, z+1/3' '-x+y, -x, z+2/3' 'x-y, -y, -z+2/3' '-x, -x+y, -z+1/3' 'y, x, -z' _cell_length_a 16.5141(6) _cell_length_b 16.5141(6) _cell_length_c 9.7096(4) _cell_angle_alpha 90 _cell_angle_beta 90 _cell_angle_gamma 120 _cell_volume 2293.20(19) _cell_formula_units_Z 6 _cell_measurement_reflns_used 9919 _cell_measurement_temperature 100 _cell_measurement_theta_max 29.105 _cell_measurement_theta_min 2.535 _shelx_estimated_absorpt_T_max 0.996 _shelx_estimated_absorpt_T_min 0.987 _exptl_absorpt_coefficient_mu 0.097 _exptl_absorpt_correction_T_max 0.7458 _exptl_absorpt_correction_T_min 0.4428 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details 'SADABS-2008/1 (Bruker,2008) was used for absorption correction. wR2(int) was 0.0968 before and 0.0703 after correction. The Ratio of minimum to maximum transmission is 0.5937. The \l/2 correction factor is 0.0015.' _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.070 _exptl_crystal_density_meas . _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 768 _exptl_crystal_size_max 0.134 _exptl_crystal_size_mid 0.063 _exptl_crystal_size_min 0.039 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0516 _diffrn_reflns_av_unetI/netI 0.0348 _diffrn_reflns_Laue_measured_fraction_full 0.986 _diffrn_reflns_Laue_measured_fraction_max 0.987 _diffrn_reflns_limit_h_max 20 _diffrn_reflns_limit_h_min -20 _diffrn_reflns_limit_k_max 20 _diffrn_reflns_limit_k_min -20 _diffrn_reflns_limit_l_max 12 _diffrn_reflns_limit_l_min -8 _diffrn_reflns_number 24980 _diffrn_reflns_point_group_measured_fraction_full 0.988 _diffrn_reflns_point_group_measured_fraction_max 0.990 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.370 _diffrn_reflns_theta_min 2.535 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 0.986 _diffrn_measured_fraction_theta_max 0.987 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type Rigaku_AFC12K_724P_007HF_Mo _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.813 _reflns_Friedel_fraction_full 0.992 _reflns_Friedel_fraction_max 0.993 _reflns_number_gt 2533 _reflns_number_total 3095 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v7.68A (Bruker, 2009)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v7.68A (Bruker, 2009)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'XL (Sheldrick, 2008)' _computing_structure_solution 'XT (Sheldrick, 2015)' _refine_diff_density_max 0.405 _refine_diff_density_min -0.272 _refine_diff_density_rms 0.074 _refine_ls_abs_structure_details ; Flack x determined using 1021 quotients [(I+)-(I-)]/[(I+)+(I-)] (Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259). ; _refine_ls_abs_structure_Flack -2.0(10) _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.062 _refine_ls_hydrogen_treatment constr _refine_ls_matrix_type full _refine_ls_number_parameters 174 _refine_ls_number_reflns 3095 _refine_ls_number_restraints 6 _refine_ls_R_factor_all 0.0740 _refine_ls_R_factor_gt 0.0638 _refine_ls_restrained_S_all 1.061 _refine_ls_shift/su_max 0.000 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.1641P)^2^+0.3647P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.2062 _refine_ls_wR_factor_ref 0.2217 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All O(H) groups 2. Restrained planarity H5, C9, O6, O5, H6 with sigma of 0.001 H4, O4, C8, O3, H3 with sigma of 0.1 O1, C7, O2, H2, H1 with sigma of 0.001 3. Others Fixed Sof: H5(0.5) H1(0.5) H4(0.5) H3(0.5) H2(0.5) H6(0.5) O1W(0.125) O7W(0.25) O2W(0.25) O6W(0.25) O5W(0.125) O3W(0.25) O4W(0.25) O8W(0.25) O9W(0.25) 4.a Aromatic/amide H refined with riding coordinates: C4(H4A), C2(H2A), C6(H6A) 4.b Idealised tetrahedral OH refined as rotating group: O5(H5), O1(H1), O4(H4), O3(H3), O2(H2), O6(H6) ; _atom_sites_solution_hydrogens geom _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O5 O 0.85082(19) 0.4629(2) 0.4973(2) 0.0299(8) Uani 1 1 d . . . . . H5 H 0.9088 0.4842 0.4945 0.045 Uiso 0.5 1 calc GR . . A 1 O1 O 0.5555(2) 0.0327(2) 0.5151(3) 0.0352(8) Uani 1 1 d . . . . . H1 H 0.5200 -0.0255 0.5140 0.053 Uiso 0.5 1 calc GR . . B 2 O4 O 0.5553(2) 0.4641(2) 0.5092(3) 0.0301(8) Uani 1 1 d . . . . . H4 H 0.5193 0.4862 0.5142 0.045 Uiso 0.5 1 calc GR . . C 1 O3 O 0.4193(2) 0.3287(2) 0.5068(3) 0.0382(8) Uani 1 1 d . . . . . H3 H 0.3976 0.3651 0.5081 0.057 Uiso 0.5 1 calc GR . . D 2 O2 O 0.4195(2) 0.0320(2) 0.5054(3) 0.0396(9) Uani 1 1 d . . . . . H2 H 0.3980 -0.0261 0.5053 0.059 Uiso 0.5 1 calc GR . . E 2 O6 O 0.8492(2) 0.3263(2) 0.5041(3) 0.0347(8) Uani 1 1 d . . . . . H6 H 0.9074 0.3617 0.5006 0.052 Uiso 0.5 1 calc GR . . F 2 C3 C 0.5599(3) 0.3235(3) 0.5124(3) 0.0242(7) Uani 1 1 d . . . . . C7 C 0.5065(3) 0.0729(2) 0.5106(3) 0.0244(6) Uani 1 1 d . . . . . C4 C 0.6569(3) 0.37205(19) 0.5099(3) 0.0214(7) Uani 1 1 d . . . . . H4A H 0.6905 0.4385 0.5102 0.026 Uiso 1 1 calc R . . . . C5 C 0.70469(19) 0.3225(3) 0.5071(3) 0.0218(6) Uani 1 1 d . . . . . C2 C 0.5101(2) 0.2260(3) 0.5127(3) 0.0245(7) Uani 1 1 d . . . . . H2A H 0.4436 0.1931 0.5137 0.029 Uiso 1 1 calc R . . . . C9 C 0.8093(2) 0.3750(3) 0.5029(3) 0.0233(6) Uani 1 1 d . . . . . C8 C 0.5076(3) 0.3757(3) 0.5097(3) 0.0243(7) Uani 1 1 d . . . . . C6 C 0.6569(3) 0.2253(3) 0.5082(3) 0.0244(8) Uani 1 1 d . . . . . H6A H 0.6900 0.1920 0.5066 0.029 Uiso 1 1 calc R . . . . C1 C 0.5590(3) 0.17750(19) 0.5115(3) 0.0229(6) Uani 1 1 d . . . . . O1W O 0.218(2) 0.0000 0.3333 0.117(10) Uiso 0.25 2 d S T P G 1 O7W O 0.7470(16) 0.0411(15) 0.268(2) 0.098(6) Uiso 0.25 1 d . . . H 7 O2W O 0.232(2) 0.058(2) 0.347(2) 0.117(7) Uiso 0.25 1 d . . . I 2 O6W O 0.076(3) 0.023(3) 0.414(5) 0.218(18) Uiso 0.25 1 d . . . J 6 O5W O 0.278(3) 0.0000 0.8333 0.128(12) Uiso 0.25 2 d S T P K 5 O3W O 0.335(2) 0.133(2) 0.882(3) 0.126(8) Uiso 0.25 1 d . . . L 3 O4W O 0.320(2) 0.127(2) 0.800(4) 0.145(10) Uiso 0.25 1 d . . . M 4 O8W O 0.771(2) 0.036(2) 0.140(3) 0.147(10) Uiso 0.25 1 d . . . N 8 O9W O 0.791(2) 0.105(2) 0.343(3) 0.141(9) Uiso 0.25 1 d . . . O 1 loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O5 0.0249(16) 0.0282(18) 0.0332(13) -0.0002(11) -0.0007(10) 0.0107(13) O1 0.0329(18) 0.0267(17) 0.0462(16) 0.0025(12) 0.0031(13) 0.0149(13) O4 0.0353(18) 0.0242(17) 0.0358(14) -0.0001(10) -0.0015(12) 0.0185(15) O3 0.0256(17) 0.0301(17) 0.0592(19) 0.0010(14) -0.0021(13) 0.0141(15) O2 0.0275(18) 0.0219(16) 0.0591(18) -0.0013(13) -0.0060(13) 0.0045(13) O6 0.0241(16) 0.0355(17) 0.0484(17) 0.0049(13) 0.0037(12) 0.0177(14) C3 0.0241(19) 0.029(2) 0.0193(12) -0.0006(14) -0.0014(13) 0.0130(13) C7 0.027(2) 0.0229(14) 0.0243(13) -0.0010(10) -0.0009(14) 0.0131(18) C4 0.020(2) 0.0204(14) 0.0182(11) -0.0002(9) 0.0014(13) 0.0054(17) C5 0.0217(15) 0.0240(19) 0.0175(11) 0.0003(12) -0.0002(9) 0.0098(17) C2 0.0232(14) 0.030(2) 0.0223(13) 0.0019(16) -0.0013(10) 0.0143(19) C9 0.0233(14) 0.027(2) 0.0196(12) 0.0011(15) 0.0003(10) 0.0131(18) C8 0.024(2) 0.025(2) 0.0225(14) 0.0002(14) -0.0012(14) 0.0114(12) C6 0.031(2) 0.026(2) 0.0190(13) -0.0030(14) -0.0024(15) 0.0161(13) C1 0.026(2) 0.0204(13) 0.0220(13) -0.0006(10) -0.0003(14) 0.0113(18) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O5 H5 0.8400 . ? O5 C9 1.259(6) . ? O1 H1 0.8400 . ? O1 C7 1.278(6) . ? O4 H4 0.8400 . ? O4 C8 1.266(6) . ? O3 H3 0.8400 . ? O3 C8 1.265(6) . ? O2 H2 0.8400 . ? O2 C7 1.246(6) . ? O6 H6 0.8400 . ? O6 C9 1.271(6) . ? C3 C4 1.388(6) . ? C3 C2 1.395(7) . ? C3 C8 1.494(4) . ? C7 C1 1.496(4) . ? C4 H4A 0.9500 . ? C4 C5 1.392(6) . ? C5 C9 1.497(4) . ? C5 C6 1.390(6) . ? C2 H2A 0.9500 . ? C2 C1 1.394(6) . ? C6 H6A 0.9500 . ? C6 C1 1.401(7) . ? O7W O7W 1.73(4) 4 ? O2W O2W 1.67(6) 4 ? O6W O6W 1.70(9) 4 ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C9 O5 H5 109.5 . . ? C7 O1 H1 109.5 . . ? C8 O4 H4 109.5 . . ? C8 O3 H3 109.5 . . ? C7 O2 H2 109.5 . . ? C9 O6 H6 109.5 . . ? C4 C3 C2 120.7(3) . . ? C4 C3 C8 120.0(4) . . ? C2 C3 C8 119.2(4) . . ? O1 C7 C1 116.5(4) . . ? O2 C7 O1 125.3(3) . . ? O2 C7 C1 118.2(4) . . ? C3 C4 H4A 120.3 . . ? C3 C4 C5 119.4(3) . . ? C5 C4 H4A 120.3 . . ? C4 C5 C9 119.2(3) . . ? C6 C5 C4 121.1(2) . . ? C6 C5 C9 119.6(3) . . ? C3 C2 H2A 120.4 . . ? C1 C2 C3 119.1(3) . . ? C1 C2 H2A 120.4 . . ? O5 C9 O6 125.1(3) . . ? O5 C9 C5 118.4(4) . . ? O6 C9 C5 116.5(4) . . ? O4 C8 C3 117.4(4) . . ? O3 C8 O4 124.7(3) . . ? O3 C8 C3 117.9(4) . . ? C5 C6 H6A 120.7 . . ? C5 C6 C1 118.7(3) . . ? C1 C6 H6A 120.7 . . ? C2 C1 C7 119.7(4) . . ? C2 C1 C6 120.9(2) . . ? C6 C1 C7 119.3(4) . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O5 H5 O1 0.84 1.78 2.605(4) 166.2 6_656 O4 H4 O4 0.84 1.79 2.613(5) 164.3 6_556 O2 H2 O6 0.84 1.79 2.615(5) 166.2 6_546 _shelx_res_file ; pc_ht_1_i233_100k.res created by SHELXL-2014/7 TITL pc_ht_1_i233_100k_a.res in P3(2)21 REM Old TITL PC_HT_1_i233_100k in P3221 #154 REM SHELXT solution in P3(2)21 REM R1 0.206, Rweak 0.006, Alpha 0.056, Orientation as input REM Flack x = -0.002 ( 0.549 ) from Parsons' quotients REM Formula found by SHELXT: C7 O1W CELL 0.71073 16.5141 16.5141 9.7096 90 90 120 ZERR 6 0.0006 0.0006 0.0004 0 0 0 LATT -1 SYMM -Y,+X-Y,0.333+Z SYMM +Y-X,-X,0.667+Z SYMM -Y+X,-Y,0.667-Z SYMM -X,-X+Y,0.333-Z SYMM +Y,+X,-Z SFAC C H O UNIT 54 60 48 EQIV $1 1+Y,+X,1-Z EQIV $2 +Y,+X,1-Z EQIV $3 +Y,-1+X,1-Z FLAT 0.001 H5 C9 O6 O5 H6 FLAT H4 O4 C8 O3 H3 FLAT 0.001 O1 C7 O2 H2 H1 L.S. 20 PLAN 20 SIZE 0.134 0.063 0.039 TEMP -173.15 HTAB O5 O1_$1 HTAB O4 O4_$2 HTAB O2 O6_$3 BOND $H list 4 fmap 2 acta SHEL 11 0.8 OMIT 0 3 1 OMIT 0 5 0 OMIT 2 2 0 OMIT -2 4 0 OMIT 2 3 0 OMIT -2 5 0 OMIT 2 3 1 OMIT -2 5 1 OMIT -2 3 1 REM REM REM WGHT 0.164100 0.364700 FVAR 0.91261 O5 3 0.850820 0.462920 0.497324 11.00000 0.02486 0.02824 = 0.03319 -0.00019 -0.00072 0.01072 PART 1 AFIX 147 H5 2 0.908837 0.484180 0.494499 10.50000 -1.50000 AFIX 0 PART 0 O1 3 0.555504 0.032746 0.515088 11.00000 0.03287 0.02667 = 0.04616 0.00248 0.00308 0.01495 PART 2 AFIX 147 H1 2 0.519996 -0.025520 0.513970 10.50000 -1.50000 AFIX 0 PART 0 O4 3 0.555284 0.464136 0.509222 11.00000 0.03526 0.02421 = 0.03578 -0.00012 -0.00154 0.01852 PART 1 AFIX 147 H4 2 0.519273 0.486206 0.514216 10.50000 -1.50000 AFIX 0 PART 0 O3 3 0.419260 0.328681 0.506831 11.00000 0.02561 0.03011 = 0.05923 0.00102 -0.00214 0.01412 PART 2 AFIX 147 H3 2 0.397608 0.365132 0.508126 10.50000 -1.50000 AFIX 0 PART 0 O2 3 0.419464 0.031963 0.505448 11.00000 0.02748 0.02191 = 0.05908 -0.00128 -0.00596 0.00453 PART 2 AFIX 147 H2 2 0.397996 -0.026117 0.505324 10.50000 -1.50000 AFIX 0 PART 0 O6 3 0.849227 0.326262 0.504097 11.00000 0.02410 0.03548 = 0.04843 0.00488 0.00372 0.01775 PART 2 AFIX 147 H6 2 0.907450 0.361746 0.500566 10.50000 -1.50000 AFIX 0 PART 0 C3 1 0.559888 0.323546 0.512399 11.00000 0.02415 0.02888 = 0.01927 -0.00062 -0.00138 0.01296 C7 1 0.506477 0.072898 0.510638 11.00000 0.02693 0.02286 = 0.02435 -0.00099 -0.00091 0.01310 C4 1 0.656928 0.372051 0.509937 11.00000 0.01952 0.02042 = 0.01821 -0.00021 0.00139 0.00539 AFIX 43 H4A 2 0.690457 0.438476 0.510181 11.00000 -1.20000 AFIX 0 C5 1 0.704686 0.322478 0.507107 11.00000 0.02171 0.02401 = 0.01746 0.00034 -0.00021 0.00982 C2 1 0.510056 0.226023 0.512694 11.00000 0.02317 0.02955 = 0.02232 0.00191 -0.00129 0.01435 AFIX 43 H2A 2 0.443635 0.193103 0.513715 11.00000 -1.20000 AFIX 0 C9 1 0.809286 0.375024 0.502922 11.00000 0.02333 0.02731 = 0.01964 0.00112 0.00031 0.01306 C8 1 0.507600 0.375704 0.509668 11.00000 0.02410 0.02520 = 0.02246 0.00017 -0.00124 0.01140 C6 1 0.656894 0.225295 0.508151 11.00000 0.03087 0.02577 = 0.01899 -0.00303 -0.00243 0.01606 AFIX 43 H6A 2 0.689971 0.191954 0.506643 11.00000 -1.20000 AFIX 0 C1 1 0.558995 0.177504 0.511471 11.00000 0.02590 0.02039 = 0.02198 -0.00057 -0.00028 0.01132 PART 1 O1W 3 0.217776 0.000000 0.333333 10.12500 0.11714 PART 0 PART 7 O7W 3 0.747047 0.041087 0.267665 10.25000 0.09843 PART 0 PART 2 O2W 3 0.232468 0.057763 0.347260 10.25000 0.11691 PART 0 PART 6 O6W 3 0.076315 0.022829 0.414153 10.25000 0.21788 PART 0 PART 5 O5W 3 0.278488 0.000000 0.833333 10.12500 0.12844 PART 0 PART 3 O3W 3 0.334999 0.133304 0.881746 10.25000 0.12625 PART 0 PART 4 O4W 3 0.319537 0.126807 0.800434 10.25000 0.14462 PART 0 PART 8 O8W 3 0.770773 0.036011 0.139671 10.25000 0.14693 PART 0 PART 1 O9W 3 0.790590 0.104557 0.343328 10.25000 0.14065 HKLF 4 REM pc_ht_1_i233_100k_a.res in P3(2)21 REM R1 = 0.0638 for 2533 Fo > 4sig(Fo) and 0.0740 for all 3095 data REM 174 parameters refined using 6 restraints END WGHT 0.1641 0.3647 REM Highest difference peak 0.405, deepest hole -0.272, 1-sigma level 0.074 Q1 1 0.2955 0.1742 0.7360 11.00000 0.05 0.40 Q2 1 0.5368 0.1313 0.5064 11.00000 0.05 0.36 Q3 1 0.2026 0.0961 0.2750 11.00000 0.05 0.31 Q4 1 0.7458 0.3419 0.5075 11.00000 0.05 0.30 Q5 1 0.1987 0.0489 0.2397 11.00000 0.05 0.29 Q6 1 0.5365 0.3418 0.5053 11.00000 0.05 0.29 Q7 1 0.3109 0.0711 0.7958 11.00000 0.05 0.26 Q8 1 0.2475 0.0617 0.8574 11.00000 0.05 0.26 Q9 1 0.2519 -0.0334 0.7823 11.00000 0.05 0.26 Q10 1 0.6091 0.2013 0.5040 11.00000 0.05 0.25 Q11 1 0.8011 0.1386 0.2831 11.00000 0.05 0.24 Q12 1 0.1937 0.0332 0.4284 11.00000 0.05 0.23 Q13 1 0.6157 0.3519 0.5029 11.00000 0.05 0.22 Q14 1 0.7948 0.0796 0.2232 11.00000 0.05 0.21 Q15 1 0.2971 0.1245 0.9760 11.00000 0.05 0.21 Q16 1 0.8558 0.4729 0.6314 11.00000 0.05 0.20 Q17 1 0.2370 0.1081 0.8275 11.00000 0.05 0.20 Q18 1 0.5717 0.5511 0.4448 11.00000 0.05 0.20 Q19 1 0.6150 0.4916 0.4862 11.00000 0.05 0.20 Q20 1 0.7427 0.0297 0.3645 11.00000 0.05 0.19 ; _shelx_res_checksum 54663 _olex2_submission_special_instructions 'No special instructions were received' ####################################################################### # # This file contains crystal structure data downloaded from the # Cambridge Structural Database (CSD) hosted by the Cambridge # Crystallographic Data Centre (CCDC). # # Full information about CCDC data access policies and citation # guidelines are available at http://www.ccdc.cam.ac.uk/access/V1 # # Audit and citation data items may have been added by the CCDC. # Please retain this information to preserve the provenance of # this file and to allow appropriate attribution of the data. # ####################################################################### data_pc_ht_1_i418_100k _database_code_depnum_ccdc_archive 'CCDC 1915311' loop_ _audit_author_name _audit_author_address 'Marc Little' ;Chemistry Department, University of Liverpool United Kingdom ; _audit_update_record ; 2019-05-10 deposited with the CCDC. 2019-08-20 downloaded from the CCDC. ; _audit_creation_date 2018-05-30 _audit_creation_method ; Olex2 1.2 (compiled 2018.05.18 svn.r3508 for OlexSys, GUI svn.r5497) ; _shelx_SHELXL_version_number 2014/7 _chemical_name_common ? _chemical_name_systematic ? _chemical_formula_moiety '2(C9 H6 O6), 2(C3 H8 O)' _chemical_formula_sum 'C24 H28 O14' _chemical_formula_weight 540.46 _chemical_melting_point ? loop_ _atom_type_symbol _atom_type_description _atom_type_scat_dispersion_real _atom_type_scat_dispersion_imag _atom_type_scat_source C C 0.0033 0.0016 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' O O 0.0106 0.0060 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4' _shelx_space_group_comment ; The symmetry employed for this shelxl refinement is uniquely defined by the following loop, which should always be used as a source of symmetry information in preference to the above space-group names. They are only intended as comments. ; _space_group_crystal_system monoclinic _space_group_IT_number 15 _space_group_name_H-M_alt 'C 1 2/c 1' _space_group_name_Hall '-C 2yc' loop_ _space_group_symop_operation_xyz 'x, y, z' '-x, y, -z+1/2' 'x+1/2, y+1/2, z' '-x+1/2, y+1/2, -z+1/2' '-x, -y, -z' 'x, -y, z-1/2' '-x+1/2, -y+1/2, -z' 'x+1/2, -y+1/2, z-1/2' _cell_length_a 19.0126(17) _cell_length_b 9.6004(8) _cell_length_c 27.383(2) _cell_angle_alpha 90 _cell_angle_beta 90.563(2) _cell_angle_gamma 90 _cell_volume 4998.0(8) _cell_formula_units_Z 8 _cell_measurement_reflns_used 7992 _cell_measurement_temperature 100 _cell_measurement_theta_max 26.369 _cell_measurement_theta_min 2.487 _shelx_estimated_absorpt_T_max 0.991 _shelx_estimated_absorpt_T_min 0.978 _exptl_absorpt_coefficient_mu 0.120 _exptl_absorpt_correction_T_max 0.7454 _exptl_absorpt_correction_T_min 0.4737 _exptl_absorpt_correction_type multi-scan _exptl_absorpt_process_details ; SADABS-2014/5 (Bruker,2014/5) was used for absorption correction. wR2(int) was 0.0956 before and 0.0675 after correction. The Ratio of minimum to maximum transmission is 0.6355. The \l/2 correction factor is 0.00150. ; _exptl_absorpt_special_details ? _exptl_crystal_colour colourless _exptl_crystal_colour_primary colourless _exptl_crystal_density_diffrn 1.437 _exptl_crystal_density_meas ? _exptl_crystal_density_method ? _exptl_crystal_description block _exptl_crystal_F_000 2272 _exptl_crystal_size_max 0.188 _exptl_crystal_size_mid 0.101 _exptl_crystal_size_min 0.079 _exptl_transmission_factor_max ? _exptl_transmission_factor_min ? _diffrn_reflns_av_R_equivalents 0.0488 _diffrn_reflns_av_unetI/netI 0.0437 _diffrn_reflns_Laue_measured_fraction_full 1.000 _diffrn_reflns_Laue_measured_fraction_max 0.998 _diffrn_reflns_limit_h_max 23 _diffrn_reflns_limit_h_min -23 _diffrn_reflns_limit_k_max 8 _diffrn_reflns_limit_k_min -12 _diffrn_reflns_limit_l_max 33 _diffrn_reflns_limit_l_min -34 _diffrn_reflns_number 23878 _diffrn_reflns_point_group_measured_fraction_full 1.000 _diffrn_reflns_point_group_measured_fraction_max 0.998 _diffrn_reflns_theta_full 25.242 _diffrn_reflns_theta_max 26.446 _diffrn_reflns_theta_min 1.487 _diffrn_ambient_temperature 100 _diffrn_detector CCD _diffrn_detector_area_resol_mean 28.5714 _diffrn_detector_type 'Rigaku Saturn724+' _diffrn_measured_fraction_theta_full 1.000 _diffrn_measured_fraction_theta_max 0.998 _diffrn_measurement_device 'AFC12 (Right): Kappa 3 circle' _diffrn_measurement_device_type 'Rigaku Saturn724+ (2x2 bin mode)' _diffrn_measurement_method 'profile data from \w-scans' _diffrn_measurement_specimen_support 'Mitegen 50um' _diffrn_radiation_collimation 0.3 _diffrn_radiation_monochromator Confocal _diffrn_radiation_probe x-ray _diffrn_radiation_type MoK\a _diffrn_radiation_wavelength 0.71073 _diffrn_source 'Rotating Anode' _diffrn_source_current 24.0 _diffrn_source_power 1.2 _diffrn_source_target Mo _diffrn_source_type 'Rotating Anode' _diffrn_source_voltage 50.0 _diffrn_standards_number 0 _reflns_Friedel_coverage 0.000 _reflns_Friedel_fraction_full . _reflns_Friedel_fraction_max . _reflns_number_gt 4122 _reflns_number_total 5145 _reflns_special_details ; Reflections were merged by SHELXL according to the crystal class for the calculation of statistics and refinement. _reflns_Friedel_fraction is defined as the number of unique Friedel pairs measured divided by the number that would be possible theoretically, ignoring centric projections and systematic absences. ; _reflns_threshold_expression 'I > 2\s(I)' _computing_cell_refinement 'SAINT v8.34A (Bruker, 2013)' _computing_data_collection ; CrystalClear-SM Expert 2.0 r7 (Rigaku, 2011) ; _computing_data_reduction 'SAINT v8.34A (Bruker, 2013)' _computing_molecular_graphics 'Olex2 (Dolomanov et al., 2009)' _computing_publication_material 'Olex2 (Dolomanov et al., 2009)' _computing_structure_refinement 'ShelXL (Sheldrick, 2015)' _computing_structure_solution 'ShelXT (Sheldrick, 2015)' _refine_diff_density_max 0.651 _refine_diff_density_min -0.317 _refine_diff_density_rms 0.072 _refine_ls_extinction_coef . _refine_ls_extinction_method none _refine_ls_goodness_of_fit_ref 1.036 _refine_ls_hydrogen_treatment mixed _refine_ls_matrix_type full _refine_ls_number_parameters 373 _refine_ls_number_reflns 5145 _refine_ls_number_restraints 3 _refine_ls_R_factor_all 0.0687 _refine_ls_R_factor_gt 0.0564 _refine_ls_restrained_S_all 1.039 _refine_ls_shift/su_max 0.001 _refine_ls_shift/su_mean 0.000 _refine_ls_structure_factor_coef Fsqd _refine_ls_weighting_details 'w=1/[\s^2^(Fo^2^)+(0.0939P)^2^+4.7971P] where P=(Fo^2^+2Fc^2^)/3' _refine_ls_weighting_scheme calc _refine_ls_wR_factor_gt 0.1501 _refine_ls_wR_factor_ref 0.1624 _refine_special_details ? _olex2_refinement_description ; 1. Fixed Uiso At 1.2 times of: All C(H) groups At 1.5 times of: All H(H) groups, All C(H,H,H) groups, All O(H) groups 2. Restrained distances O1-H1 = O11-H11 0.82 with sigma of 0.02 H11-C17 1.85 with sigma of 0.02 3. Others Fixed Sof: H5(0.5) H6(0.5) H7(0.5) H8(0.5) 4.a Ternary CH refined with riding coordinates: C20(H20), C23(H23) 4.b Aromatic/amide H refined with riding coordinates: C2(H2), C4(H4), C6(H6A), C11(H11A), C13(H13), C15(H15) 4.c Idealised Me refined as rotating group: C19(H19A,H19B,H19C), C21(H21A,H21B,H21C), C22(H22A,H22B,H22C), C24(H24A,H24B, H24C) 4.d Idealised tetrahedral OH refined as rotating group: O5(H5), O6(H6), O7(H7), O8(H8) ; _atom_sites_solution_hydrogens mixed _atom_sites_solution_primary dual _atom_sites_solution_secondary ? loop_ _atom_site_label _atom_site_type_symbol _atom_site_fract_x _atom_site_fract_y _atom_site_fract_z _atom_site_U_iso_or_equiv _atom_site_adp_type _atom_site_occupancy _atom_site_site_symmetry_order _atom_site_calc_flag _atom_site_refinement_flags_posn _atom_site_refinement_flags_adp _atom_site_refinement_flags_occupancy _atom_site_disorder_assembly _atom_site_disorder_group O1 O 0.69648(8) 0.36151(14) 0.55617(5) 0.0267(3) Uani 1 1 d D . . . . O2 O 0.71555(8) 0.44888(14) 0.63107(5) 0.0262(3) Uani 1 1 d . . . . . O3 O 0.71761(7) 0.96892(14) 0.64556(5) 0.0231(3) Uani 1 1 d . . . . . O4 O 0.69764(8) 1.09830(14) 0.57887(5) 0.0267(3) Uani 1 1 d . . . . . O5 O 0.63354(7) 0.87680(14) 0.42412(4) 0.0230(3) Uani 1 1 d . . . . . H5 H 0.6264 0.8704 0.3939 0.034 Uiso 0.5 1 calc GR . P A 1 O6 O 0.63714(7) 0.64380(14) 0.41790(5) 0.0249(3) Uani 1 1 d . . . . . H6 H 0.6269 0.6627 0.3887 0.037 Uiso 0.5 1 calc GR . P B 2 C1 C 0.68848(9) 0.60339(19) 0.56528(6) 0.0174(4) Uani 1 1 d . . . . . C2 C 0.66979(9) 0.61385(19) 0.51612(6) 0.0177(4) Uani 1 1 d . . . . . H2 H 0.6643 0.5321 0.4969 0.021 Uiso 1 1 calc R . . . . C3 C 0.65911(9) 0.74486(19) 0.49505(6) 0.0171(4) Uani 1 1 d . . . . . C4 C 0.66828(9) 0.86457(19) 0.52286(6) 0.0173(4) Uani 1 1 d . . . . . H4 H 0.6613 0.9537 0.5085 0.021 Uiso 1 1 calc R . . . . C5 C 0.68773(9) 0.85356(19) 0.57194(6) 0.0174(4) Uani 1 1 d . . . . . C6 C 0.69699(9) 0.72309(19) 0.59357(6) 0.0178(4) Uani 1 1 d . . . . . H6A H 0.7090 0.7159 0.6272 0.021 Uiso 1 1 calc R . . . . C7 C 0.70166(9) 0.46362(19) 0.58799(6) 0.0177(4) Uani 1 1 d . . . . . C8 C 0.64173(9) 0.75493(19) 0.44223(6) 0.0166(4) Uani 1 1 d . . . . . C9 C 0.70145(9) 0.9855(2) 0.59939(6) 0.0189(4) Uani 1 1 d . . . . . O7 O 0.61573(7) 1.34422(14) 0.82386(5) 0.0239(3) Uani 1 1 d . . . . . H7 H 0.6200 1.3376 0.8543 0.036 Uiso 0.5 1 calc GR . P C 2 O8 O 0.61683(7) 1.11103(14) 0.82912(4) 0.0218(3) Uani 1 1 d . . . . . H8 H 0.6246 1.1295 0.8587 0.033 Uiso 0.5 1 calc GR . P D 1 O9 O 0.55576(8) 0.83243(14) 0.68981(5) 0.0284(3) Uani 1 1 d . . . . . O10 O 0.53336(7) 0.92163(14) 0.61570(5) 0.0248(3) Uani 1 1 d . . . . . O11 O 0.53088(8) 1.44126(14) 0.60270(5) 0.0252(3) Uani 1 1 d D . . . . O12 O 0.54648(8) 1.56819(14) 0.67016(5) 0.0264(3) Uani 1 1 d . . . . . C10 C 0.59063(9) 1.21422(19) 0.75269(6) 0.0162(4) Uani 1 1 d . . . . . C11 C 0.57868(9) 1.33437(18) 0.72549(6) 0.0165(4) Uani 1 1 d . . . . . H11A H 0.5836 1.4232 0.7404 0.020 Uiso 1 1 calc R . . . . C12 C 0.55949(9) 1.32448(19) 0.67633(6) 0.0172(4) Uani 1 1 d . . . . . C13 C 0.55156(9) 1.19518(19) 0.65422(6) 0.0169(4) Uani 1 1 d . . . . . H13 H 0.5393 1.1889 0.6206 0.020 Uiso 1 1 calc R . . . . C14 C 0.56178(9) 1.07457(19) 0.68186(6) 0.0170(4) Uani 1 1 d . . . . . C15 C 0.58206(9) 1.08374(18) 0.73074(6) 0.0157(4) Uani 1 1 d . . . . . H15 H 0.5901 1.0013 0.7492 0.019 Uiso 1 1 calc R . . . . C16 C 0.60917(9) 1.22306(18) 0.80543(6) 0.0160(4) Uani 1 1 d . . . . . C17 C 0.54518(9) 1.45685(18) 0.64924(6) 0.0184(4) Uani 1 1 d D . . . . C18 C 0.54894(9) 0.93554(19) 0.65871(6) 0.0185(4) Uani 1 1 d . . . . . O13 O 0.75891(7) 0.70756(14) 0.81418(5) 0.0236(3) Uani 1 1 d . . . . . C19 C 0.63194(11) 0.7285(2) 0.80337(7) 0.0286(5) Uani 1 1 d . . . . . H19A H 0.6247 0.6397 0.8203 0.043 Uiso 1 1 calc GR . . . . H19B H 0.5947 0.7417 0.7788 0.043 Uiso 1 1 calc GR . . . . H19C H 0.6306 0.8049 0.8271 0.043 Uiso 1 1 calc GR . . . . C20 C 0.70270(10) 0.7270(2) 0.77855(6) 0.0222(4) Uani 1 1 d . . . . . H20 H 0.7097 0.8183 0.7617 0.027 Uiso 1 1 calc R . . . . C21 C 0.70957(11) 0.6120(2) 0.74193(7) 0.0289(5) Uani 1 1 d . . . . . H21A H 0.7562 0.6159 0.7271 0.043 Uiso 1 1 calc GR . . . . H21B H 0.6734 0.6227 0.7165 0.043 Uiso 1 1 calc GR . . . . H21C H 0.7035 0.5220 0.7583 0.043 Uiso 1 1 calc GR . . . . O14 O 0.50478(7) 0.67657(14) 0.56196(5) 0.0255(3) Uani 1 1 d . . . . . C22 C 0.46024(11) 0.8183(2) 0.49502(7) 0.0332(5) Uani 1 1 d . . . . . H22A H 0.4668 0.9041 0.5139 0.050 Uiso 1 1 calc GR . . . . H22B H 0.4205 0.8298 0.4723 0.050 Uiso 1 1 calc GR . . . . H22C H 0.5030 0.7985 0.4766 0.050 Uiso 1 1 calc GR . . . . C23 C 0.44554(10) 0.6992(2) 0.52922(6) 0.0231(4) Uani 1 1 d . . . . . H23 H 0.4388 0.6131 0.5092 0.028 Uiso 1 1 calc R . . . . C24 C 0.37896(11) 0.7241(2) 0.55774(7) 0.0313(5) Uani 1 1 d . . . . . H24A H 0.3716 0.6467 0.5805 0.047 Uiso 1 1 calc GR . . . . H24B H 0.3388 0.7304 0.5351 0.047 Uiso 1 1 calc GR . . . . H24C H 0.3833 0.8113 0.5761 0.047 Uiso 1 1 calc GR . . . . H14 H 0.5145(9) 0.766(2) 0.5742(6) 0.003(4) Uiso 1 1 d . . . . . H3 H 0.7268(15) 1.052(3) 0.6574(10) 0.054(8) Uiso 1 1 d . . . . . H13A H 0.7657(16) 0.784(3) 0.8298(11) 0.057(9) Uiso 1 1 d . . . . . H9 H 0.547(2) 0.744(4) 0.6802(13) 0.085 Uiso 1 1 d R . . . . H1 H 0.7013(16) 0.279(2) 0.5683(10) 0.051(8) Uiso 1 1 d D . . . . H11 H 0.5194(17) 1.526(2) 0.5908(8) 0.077 Uiso 1 1 d DR . . . . loop_ _atom_site_aniso_label _atom_site_aniso_U_11 _atom_site_aniso_U_22 _atom_site_aniso_U_33 _atom_site_aniso_U_23 _atom_site_aniso_U_13 _atom_site_aniso_U_12 O1 0.0452(9) 0.0133(7) 0.0215(7) 0.0005(5) -0.0048(6) 0.0013(6) O2 0.0410(8) 0.0181(7) 0.0194(7) 0.0028(5) -0.0052(6) 0.0019(6) O3 0.0338(8) 0.0172(7) 0.0182(6) -0.0014(5) -0.0036(5) 0.0006(6) O4 0.0402(8) 0.0143(7) 0.0256(7) -0.0001(5) -0.0059(6) -0.0010(6) O5 0.0307(7) 0.0214(7) 0.0167(6) 0.0052(5) -0.0041(5) 0.0022(6) O6 0.0308(8) 0.0235(7) 0.0201(6) -0.0013(5) -0.0060(6) -0.0006(6) C1 0.0170(9) 0.0164(9) 0.0189(8) 0.0022(7) 0.0011(6) 0.0003(7) C2 0.0158(9) 0.0184(9) 0.0189(8) 0.0008(7) 0.0003(6) -0.0005(7) C3 0.0156(9) 0.0194(9) 0.0164(8) 0.0019(7) -0.0014(7) -0.0002(7) C4 0.0155(9) 0.0188(9) 0.0175(8) 0.0014(7) 0.0010(6) 0.0012(7) C5 0.0177(9) 0.0162(9) 0.0183(8) 0.0002(7) 0.0000(7) -0.0002(7) C6 0.0169(9) 0.0196(9) 0.0171(8) 0.0016(7) 0.0013(7) 0.0007(7) C7 0.0186(9) 0.0160(9) 0.0184(8) 0.0004(7) 0.0001(7) -0.0007(7) C8 0.0136(9) 0.0187(9) 0.0175(8) 0.0022(7) -0.0004(6) -0.0001(7) C9 0.0194(9) 0.0199(9) 0.0173(8) 0.0002(7) -0.0005(7) 0.0023(7) O7 0.0323(8) 0.0176(7) 0.0215(6) -0.0053(5) -0.0067(6) -0.0017(5) O8 0.0296(7) 0.0197(7) 0.0160(6) 0.0028(5) -0.0040(5) 0.0016(5) O9 0.0492(9) 0.0122(7) 0.0235(7) -0.0011(5) -0.0072(6) -0.0036(6) O10 0.0363(8) 0.0174(7) 0.0208(6) -0.0029(5) -0.0042(5) -0.0005(6) O11 0.0394(8) 0.0155(7) 0.0205(7) 0.0016(5) -0.0053(6) 0.0024(6) O12 0.0406(8) 0.0116(7) 0.0268(7) 0.0001(5) -0.0067(6) 0.0009(6) C10 0.0150(9) 0.0174(9) 0.0162(8) 0.0004(7) -0.0009(6) -0.0009(7) C11 0.0168(9) 0.0128(8) 0.0198(8) 0.0001(6) 0.0000(6) -0.0015(7) C12 0.0157(8) 0.0159(9) 0.0202(8) 0.0043(7) 0.0007(7) 0.0010(7) C13 0.0183(9) 0.0158(9) 0.0166(8) 0.0010(7) 0.0003(7) 0.0001(7) C14 0.0172(9) 0.0157(9) 0.0181(8) -0.0015(7) 0.0004(6) -0.0001(7) C15 0.0160(9) 0.0136(8) 0.0175(8) 0.0013(6) 0.0005(6) 0.0003(6) C16 0.0155(9) 0.0150(9) 0.0174(8) 0.0010(6) -0.0011(6) -0.0008(6) C17 0.0194(9) 0.0132(9) 0.0226(8) 0.0019(7) -0.0004(7) -0.0005(7) C18 0.0175(9) 0.0162(9) 0.0217(9) -0.0040(7) 0.0008(7) -0.0006(7) O13 0.0319(8) 0.0168(7) 0.0220(7) -0.0010(5) -0.0082(6) -0.0003(6) C19 0.0322(12) 0.0274(11) 0.0261(10) -0.0018(8) -0.0007(8) 0.0079(9) C20 0.0303(11) 0.0181(9) 0.0182(8) 0.0018(7) -0.0057(7) -0.0016(8) C21 0.0274(11) 0.0334(12) 0.0258(10) -0.0076(8) 0.0009(8) -0.0035(9) O14 0.0358(8) 0.0150(7) 0.0255(7) 0.0011(5) -0.0099(6) 0.0010(6) C22 0.0292(11) 0.0416(13) 0.0286(10) 0.0109(9) -0.0013(8) -0.0015(10) C23 0.0291(10) 0.0229(10) 0.0172(8) -0.0005(7) -0.0061(7) 0.0006(8) C24 0.0319(12) 0.0340(12) 0.0280(10) -0.0027(9) 0.0015(8) -0.0018(9) _geom_special_details ; All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. ; loop_ _geom_bond_atom_site_label_1 _geom_bond_atom_site_label_2 _geom_bond_distance _geom_bond_site_symmetry_2 _geom_bond_publ_flag O1 C7 1.315(2) . ? O1 H1 0.859(17) . ? O2 C7 1.214(2) . ? O3 C9 1.308(2) . ? O3 H3 0.88(3) . ? O4 C9 1.222(2) . ? O5 H5 0.8400 . ? O5 C8 1.280(2) . ? O6 H6 0.8400 . ? O6 C8 1.260(2) . ? C1 C2 1.393(2) . ? C1 C6 1.394(3) . ? C1 C7 1.499(2) . ? C2 H2 0.9500 . ? C2 C3 1.398(3) . ? C3 C4 1.389(3) . ? C3 C8 1.484(2) . ? C4 H4 0.9500 . ? C4 C5 1.394(2) . ? C5 C6 1.396(3) . ? C5 C9 1.495(2) . ? C6 H6A 0.9500 . ? O7 H7 0.8400 . ? O7 C16 1.274(2) . ? O8 H8 0.8400 . ? O8 C16 1.264(2) . ? O9 C18 1.311(2) . ? O9 H9 0.90(4) . ? O10 C18 1.219(2) . ? O11 C17 1.309(2) . ? O11 H11 0.901(17) . ? O12 C17 1.213(2) . ? C10 C11 1.391(2) . ? C10 C15 1.398(2) . ? C10 C16 1.486(2) . ? C11 H11A 0.9500 . ? C11 C12 1.394(2) . ? C12 C13 1.389(2) . ? C12 C17 1.495(2) . ? C13 H13 0.9500 . ? C13 C14 1.396(2) . ? C14 C15 1.392(2) . ? C14 C18 1.497(2) . ? C15 H15 0.9500 . ? O13 C20 1.452(2) . ? O13 H13A 0.86(3) . ? C19 H19A 0.9800 . ? C19 H19B 0.9800 . ? C19 H19C 0.9800 . ? C19 C20 1.513(3) . ? C20 H20 1.0000 . ? C20 C21 1.499(3) . ? C21 H21A 0.9800 . ? C21 H21B 0.9800 . ? C21 H21C 0.9800 . ? O14 C23 1.449(2) . ? O14 H14 0.940(19) . ? C22 H22A 0.9800 . ? C22 H22B 0.9800 . ? C22 H22C 0.9800 . ? C22 C23 1.506(3) . ? C23 H23 1.0000 . ? C23 C24 1.513(3) . ? C24 H24A 0.9800 . ? C24 H24B 0.9800 . ? C24 H24C 0.9800 . ? loop_ _geom_angle_atom_site_label_1 _geom_angle_atom_site_label_2 _geom_angle_atom_site_label_3 _geom_angle _geom_angle_site_symmetry_1 _geom_angle_site_symmetry_3 _geom_angle_publ_flag C7 O1 H1 115(2) . . ? C9 O3 H3 107.0(19) . . ? C8 O5 H5 109.5 . . ? C8 O6 H6 109.5 . . ? C2 C1 C6 120.31(17) . . ? C2 C1 C7 120.38(16) . . ? C6 C1 C7 119.29(15) . . ? C1 C2 H2 120.0 . . ? C1 C2 C3 119.90(16) . . ? C3 C2 H2 120.0 . . ? C2 C3 C8 119.41(16) . . ? C4 C3 C2 120.10(16) . . ? C4 C3 C8 120.41(16) . . ? C3 C4 H4 120.1 . . ? C3 C4 C5 119.76(17) . . ? C5 C4 H4 120.1 . . ? C4 C5 C6 120.55(16) . . ? C4 C5 C9 117.64(16) . . ? C6 C5 C9 121.75(15) . . ? C1 C6 C5 119.35(16) . . ? C1 C6 H6A 120.3 . . ? C5 C6 H6A 120.3 . . ? O1 C7 C1 112.41(15) . . ? O2 C7 O1 124.83(17) . . ? O2 C7 C1 122.76(16) . . ? O5 C8 C3 117.55(16) . . ? O6 C8 O5 124.17(16) . . ? O6 C8 C3 118.28(16) . . ? O3 C9 C5 114.92(16) . . ? O4 C9 O3 124.38(17) . . ? O4 C9 C5 120.70(16) . . ? C16 O7 H7 109.5 . . ? C16 O8 H8 109.5 . . ? C18 O9 H9 120(2) . . ? C17 O11 H11 107.2(16) . . ? C11 C10 C15 119.68(15) . . ? C11 C10 C16 120.62(16) . . ? C15 C10 C16 119.64(15) . . ? C10 C11 H11A 120.0 . . ? C10 C11 C12 120.03(16) . . ? C12 C11 H11A 120.0 . . ? C11 C12 C17 117.76(16) . . ? C13 C12 C11 120.53(16) . . ? C13 C12 C17 121.67(15) . . ? C12 C13 H13 120.3 . . ? C12 C13 C14 119.42(16) . . ? C14 C13 H13 120.3 . . ? C13 C14 C18 119.27(15) . . ? C15 C14 C13 120.31(16) . . ? C15 C14 C18 120.40(16) . . ? C10 C15 H15 120.0 . . ? C14 C15 C10 119.99(16) . . ? C14 C15 H15 120.0 . . ? O7 C16 C10 117.31(15) . . ? O8 C16 O7 124.30(15) . . ? O8 C16 C10 118.39(15) . . ? O11 C17 C12 114.89(15) . . ? O12 C17 O11 124.31(16) . . ? O12 C17 C12 120.79(16) . . ? O9 C18 C14 112.55(15) . . ? O10 C18 O9 124.49(17) . . ? O10 C18 C14 122.96(17) . . ? C20 O13 H13A 109(2) . . ? H19A C19 H19B 109.5 . . ? H19A C19 H19C 109.5 . . ? H19B C19 H19C 109.5 . . ? C20 C19 H19A 109.5 . . ? C20 C19 H19B 109.5 . . ? C20 C19 H19C 109.5 . . ? O13 C20 C19 110.55(15) . . ? O13 C20 H20 108.8 . . ? O13 C20 C21 106.64(15) . . ? C19 C20 H20 108.8 . . ? C21 C20 C19 113.01(16) . . ? C21 C20 H20 108.8 . . ? C20 C21 H21A 109.5 . . ? C20 C21 H21B 109.5 . . ? C20 C21 H21C 109.5 . . ? H21A C21 H21B 109.5 . . ? H21A C21 H21C 109.5 . . ? H21B C21 H21C 109.5 . . ? C23 O14 H14 103.4(11) . . ? H22A C22 H22B 109.5 . . ? H22A C22 H22C 109.5 . . ? H22B C22 H22C 109.5 . . ? C23 C22 H22A 109.5 . . ? C23 C22 H22B 109.5 . . ? C23 C22 H22C 109.5 . . ? O14 C23 C22 110.53(16) . . ? O14 C23 H23 108.1 . . ? O14 C23 C24 110.71(15) . . ? C22 C23 H23 108.1 . . ? C22 C23 C24 111.24(17) . . ? C24 C23 H23 108.1 . . ? C23 C24 H24A 109.5 . . ? C23 C24 H24B 109.5 . . ? C23 C24 H24C 109.5 . . ? H24A C24 H24B 109.5 . . ? H24A C24 H24C 109.5 . . ? H24B C24 H24C 109.5 . . ? loop_ _geom_hbond_atom_site_label_D _geom_hbond_atom_site_label_H _geom_hbond_atom_site_label_A _geom_hbond_distance_DH _geom_hbond_distance_HA _geom_hbond_distance_DA _geom_hbond_angle_DHA _geom_hbond_site_symmetry_A O5 H5 O8 0.84 1.79 2.6202(18) 169.5 6_575 O6 H6 O7 0.84 1.79 2.6056(18) 163.8 6_575 O7 H7 O6 0.84 1.78 2.6056(18) 168.8 6_576 O8 H8 O5 0.84 1.80 2.6202(19) 165.1 6_576 O14 H14 O10 0.940(19) 1.909(19) 2.8251(19) 164.2(16) . O3 H3 O13 0.88(3) 1.70(3) 2.5795(19) 174(3) 4_656 O13 H13A O2 0.86(3) 1.94(3) 2.7993(19) 176(3) 4_656 O9 H9 O12 0.90(4) 1.71(4) 2.5989(19) 167(4) 1_545 O1 H1 O4 0.859(17) 1.765(19) 2.6023(19) 164(3) 1_545 O11 H11 O14 0.901(17) 1.671(16) 2.5658(18) 172(3) 1_565 _shelx_res_file ; pc_ht_1_i418_100k.res created by SHELXL-2014/7 TITL pc_ht_1_i418_100k_a.res in C2/c REM Old TITL PC_HT_1_i418_100K in C2/c REM SHELXT solution in C2/c REM R1 0.125, Rweak 0.002, Alpha 0.022, Orientation as input REM Formula found by SHELXT: C24 O14 CELL 0.71073 19.0126 9.6004 27.3832 90 90.563 90 ZERR 8 0.0017 0.0008 0.0024 0 0.002 0 LATT 7 SYMM -X,+Y,0.5-Z SFAC C H O UNIT 192 224 112 EQIV $1 +X,-1+Y,+Z EQIV $2 1.5-X,0.5+Y,1.5-Z EQIV $3 +X,2-Y,-0.5+Z EQIV $4 +X,2-Y,0.5+Z EQIV $5 +X,1+Y,+Z DFIX 0.82 O1 H1 O11 H11 DANG 1.85 0.02 H11 C17 L.S. 20 PLAN 20 SIZE 0.079 0.101 0.188 TEMP -173.15 HTAB O1 O4_$1 HTAB O3 O13_$2 HTAB O5 O8_$3 HTAB O6 O7_$3 HTAB O7 O6_$4 HTAB O8 O5_$4 HTAB O9 O12_$1 HTAB O11 O14_$5 HTAB O13 O2_$2 HTAB O14 O10 BOND $H list 4 fmap 2 53 ACTA REM REM REM WGHT 0.093900 4.797100 FVAR 0.16667 O1 3 0.696477 0.361507 0.556165 11.00000 0.04516 0.01331 = 0.02153 0.00047 -0.00481 0.00131 O2 3 0.715548 0.448880 0.631070 11.00000 0.04096 0.01806 = 0.01938 0.00276 -0.00517 0.00190 O3 3 0.717611 0.968922 0.645557 11.00000 0.03376 0.01721 = 0.01824 -0.00145 -0.00359 0.00061 O4 3 0.697645 1.098299 0.578872 11.00000 0.04017 0.01427 = 0.02564 -0.00008 -0.00591 -0.00101 O5 3 0.633536 0.876798 0.424121 11.00000 0.03067 0.02145 = 0.01670 0.00521 -0.00407 0.00219 PART 1 AFIX 147 H5 2 0.626366 0.870427 0.393885 10.50000 -1.50000 AFIX 0 PART 0 O6 3 0.637136 0.643798 0.417900 11.00000 0.03082 0.02353 = 0.02012 -0.00128 -0.00599 -0.00059 PART 2 AFIX 147 H6 2 0.626869 0.662747 0.388743 10.50000 -1.50000 AFIX 0 PART 0 C1 1 0.688477 0.603387 0.565284 11.00000 0.01696 0.01644 = 0.01890 0.00222 0.00106 0.00025 C2 1 0.669789 0.613851 0.516119 11.00000 0.01578 0.01839 = 0.01895 0.00077 0.00029 -0.00049 AFIX 43 H2 2 0.664311 0.532064 0.496926 11.00000 -1.20000 AFIX 0 C3 1 0.659106 0.744859 0.495052 11.00000 0.01556 0.01936 = 0.01642 0.00188 -0.00136 -0.00017 C4 1 0.668279 0.864575 0.522860 11.00000 0.01549 0.01884 = 0.01750 0.00137 0.00102 0.00119 AFIX 43 H4 2 0.661325 0.953655 0.508498 11.00000 -1.20000 AFIX 0 C5 1 0.687733 0.853557 0.571938 11.00000 0.01772 0.01621 = 0.01830 0.00019 0.00000 -0.00023 C6 1 0.696990 0.723091 0.593575 11.00000 0.01689 0.01960 = 0.01706 0.00162 0.00129 0.00071 AFIX 43 H6A 2 0.708973 0.715926 0.627243 11.00000 -1.20000 AFIX 0 C7 1 0.701664 0.463624 0.587995 11.00000 0.01857 0.01601 = 0.01837 0.00040 0.00008 -0.00071 C8 1 0.641726 0.754930 0.442230 11.00000 0.01356 0.01871 = 0.01748 0.00216 -0.00036 -0.00011 C9 1 0.701449 0.985494 0.599393 11.00000 0.01942 0.01987 = 0.01730 0.00022 -0.00048 0.00226 O7 3 0.615727 1.344215 0.823864 11.00000 0.03234 0.01763 = 0.02149 -0.00528 -0.00666 -0.00168 PART 2 AFIX 147 H7 2 0.620033 1.337649 0.854336 10.50000 -1.50000 AFIX 0 PART 0 O8 3 0.616833 1.111027 0.829122 11.00000 0.02958 0.01968 = 0.01603 0.00283 -0.00404 0.00162 PART 1 AFIX 147 H8 2 0.624577 1.129477 0.858675 10.50000 -1.50000 AFIX 0 PART 0 O9 3 0.555761 0.832435 0.689809 11.00000 0.04922 0.01223 = 0.02353 -0.00112 -0.00718 -0.00356 O10 3 0.533360 0.921631 0.615704 11.00000 0.03628 0.01735 = 0.02078 -0.00287 -0.00423 -0.00051 O11 3 0.530877 1.441262 0.602695 11.00000 0.03937 0.01548 = 0.02050 0.00157 -0.00528 0.00239 O12 3 0.546480 1.568190 0.670164 11.00000 0.04063 0.01164 = 0.02682 0.00015 -0.00667 0.00093 C10 1 0.590633 1.214218 0.752690 11.00000 0.01501 0.01737 = 0.01615 0.00036 -0.00085 -0.00093 C11 1 0.578684 1.334367 0.725485 11.00000 0.01677 0.01280 = 0.01982 0.00012 0.00001 -0.00150 AFIX 43 H11A 2 0.583600 1.423228 0.740397 11.00000 -1.20000 AFIX 0 C12 1 0.559493 1.324482 0.676332 11.00000 0.01566 0.01585 = 0.02024 0.00434 0.00068 0.00099 C13 1 0.551563 1.195178 0.654223 11.00000 0.01832 0.01583 = 0.01659 0.00100 0.00031 0.00006 AFIX 43 H13 2 0.539294 1.188861 0.620581 11.00000 -1.20000 AFIX 0 C14 1 0.561775 1.074572 0.681863 11.00000 0.01721 0.01569 = 0.01806 -0.00145 0.00039 -0.00007 C15 1 0.582065 1.083737 0.730744 11.00000 0.01602 0.01361 = 0.01751 0.00127 0.00047 0.00028 AFIX 43 H15 2 0.590087 1.001345 0.749188 11.00000 -1.20000 AFIX 0 C16 1 0.609169 1.223057 0.805432 11.00000 0.01553 0.01503 = 0.01735 0.00097 -0.00110 -0.00084 C17 1 0.545184 1.456854 0.649242 11.00000 0.01939 0.01321 = 0.02256 0.00194 -0.00044 -0.00054 C18 1 0.548944 0.935540 0.658713 11.00000 0.01750 0.01620 = 0.02169 -0.00397 0.00084 -0.00057 O13 3 0.758905 0.707561 0.814184 11.00000 0.03194 0.01677 = 0.02197 -0.00096 -0.00819 -0.00031 C19 1 0.631935 0.728482 0.803369 11.00000 0.03215 0.02742 = 0.02612 -0.00179 -0.00071 0.00792 AFIX 137 H19A 2 0.624735 0.639746 0.820290 11.00000 -1.50000 H19B 2 0.594663 0.741703 0.778832 11.00000 -1.50000 H19C 2 0.630582 0.804927 0.827059 11.00000 -1.50000 AFIX 0 C20 1 0.702699 0.727045 0.778550 11.00000 0.03029 0.01806 = 0.01822 0.00178 -0.00568 -0.00157 AFIX 13 H20 2 0.709718 0.818261 0.761652 11.00000 -1.20000 AFIX 0 C21 1 0.709568 0.611956 0.741929 11.00000 0.02741 0.03341 = 0.02582 -0.00759 0.00091 -0.00346 AFIX 137 H21A 2 0.756243 0.615930 0.727123 11.00000 -1.50000 H21B 2 0.673403 0.622717 0.716460 11.00000 -1.50000 H21C 2 0.703549 0.521966 0.758256 11.00000 -1.50000 AFIX 0 O14 3 0.504780 0.676567 0.561955 11.00000 0.03577 0.01499 = 0.02547 0.00108 -0.00988 0.00098 C22 1 0.460239 0.818317 0.495020 11.00000 0.02924 0.04159 = 0.02864 0.01085 -0.00130 -0.00149 AFIX 137 H22A 2 0.466768 0.904125 0.513912 11.00000 -1.50000 H22B 2 0.420502 0.829793 0.472310 11.00000 -1.50000 H22C 2 0.503013 0.798542 0.476583 11.00000 -1.50000 AFIX 0 C23 1 0.445535 0.699200 0.529223 11.00000 0.02915 0.02285 = 0.01722 -0.00048 -0.00613 0.00060 AFIX 13 H23 2 0.438776 0.613064 0.509185 11.00000 -1.20000 AFIX 0 C24 1 0.378962 0.724111 0.557744 11.00000 0.03188 0.03399 = 0.02795 -0.00269 0.00151 -0.00181 AFIX 137 H24A 2 0.371603 0.646726 0.580467 11.00000 -1.50000 H24B 2 0.338839 0.730429 0.535112 11.00000 -1.50000 H24C 2 0.383319 0.811317 0.576129 11.00000 -1.50000 AFIX 0 H14 2 0.514460 0.766160 0.574164 11.00000 0.00282 H3 2 0.726791 1.051913 0.657432 11.00000 0.05436 H13A 2 0.765667 0.783725 0.829840 11.00000 0.05677 H9 2 0.547086 0.744383 0.680236 11.00000 -1.50000 H1 2 0.701316 0.279455 0.568252 11.00000 0.05143 H11 2 0.519436 1.525831 0.590786 11.00000 -1.50000 HKLF 4 REM pc_ht_1_i418_100k_a.res in C2/c REM R1 = 0.0564 for 4122 Fo > 4sig(Fo) and 0.0687 for all 5145 data REM 373 parameters refined using 3 restraints END WGHT 0.0939 4.7697 REM Highest difference peak 0.651, deepest hole -0.317, 1-sigma level 0.072 Q1 1 0.5545 1.6262 0.6998 11.00000 0.05 0.65 Q2 1 0.5357 1.5490 0.6214 11.00000 0.05 0.51 Q3 1 0.5368 1.0247 0.6049 11.00000 0.05 0.49 Q4 1 0.4631 0.6053 0.4858 11.00000 0.05 0.45 Q5 1 0.5820 1.1553 0.7397 11.00000 0.05 0.41 Q6 1 0.4568 0.7764 0.5252 11.00000 0.05 0.37 Q7 1 0.5994 1.2191 0.7780 11.00000 0.05 0.37 Q8 1 0.7184 0.5571 0.6537 11.00000 0.05 0.36 Q9 1 0.6164 1.1435 0.8256 11.00000 0.05 0.34 Q10 1 0.5597 1.1264 0.6802 11.00000 0.05 0.34 Q11 1 0.4609 0.9087 0.4985 11.00000 0.05 0.33 Q12 1 0.5497 1.2750 0.6619 11.00000 0.05 0.33 Q13 1 0.7165 0.8043 0.7440 11.00000 0.05 0.32 Q14 1 0.5457 0.8842 0.6811 11.00000 0.05 0.32 Q15 1 0.6951 0.6706 0.5811 11.00000 0.05 0.31 Q16 1 0.5569 1.5642 0.6616 11.00000 0.05 0.29 Q17 1 0.5904 1.2516 0.7429 11.00000 0.05 0.29 Q18 1 0.7619 0.8198 0.7981 11.00000 0.05 0.29 Q19 1 0.5492 1.0148 0.6623 11.00000 0.05 0.28 Q20 1 0.5156 0.7994 0.5581 11.00000 0.05 0.28 ; _shelx_res_checksum 5461 _olex2_submission_special_instructions 'No special instructions were received'