pathway_name,pathway_source,num_overlapping_genes,overlapping_genes,num_all_pathway_genes,P_genes,Q_genes,,
Beta-catenin independent WNT signaling,Reactome,3,KGP1_HUMAN;ITPR3_HUMAN;DVL1_HUMAN,92 (92),0.000974,1,0.000704225,71
CLEC7A (Dectin-1) signaling,Reactome,2,ITPR3_HUMAN;NFKB2_HUMAN,40 (40),0.00329,1,,
Ca2+ pathway,Reactome,2,KGP1_HUMAN;ITPR3_HUMAN,53 (53),0.00571,1,,
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA,Reactome,1,IF2B2_HUMAN,3 (3),0.00642,1,,
Long-term depression - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,60 (60),0.00727,1,,
Lung fibrosis,Wikipathways,2,GREM1_HUMAN;STN1_HUMAN,63 (64),0.00799,1,,
PKMTs methylate histone lysines,Reactome,2,KMT2B_HUMAN;NFKB2_HUMAN,72 (73),0.0103,1,,
pyrimidine deoxyribonucleosides salvage,HumanCyc,1,DCK_HUMAN,5 (5),0.0107,1,,
Negative regulation of TCF-dependent signaling by DVL-interacting proteins,Reactome,1,DVL1_HUMAN,5 (5),0.0107,1,,
Alternative NF-kappaB pathway,PID,1,NFKB2_HUMAN,6 (6),0.0128,1,,
C-type lectin receptors (CLRs),Reactome,2,ITPR3_HUMAN;NFKB2_HUMAN,83 (83),0.0136,1,,
MicroRNAs in cardiomyocyte hypertrophy,Wikipathways,2,KGP1_HUMAN;DVL1_HUMAN,83 (102),0.0136,1,,
Interleukin-1 processing,Reactome,1,NFKB2_HUMAN,7 (7),0.0149,1,,
Gap junction - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,88 (88),0.0151,1,,
Platelet homeostasis,Reactome,2,KGP1_HUMAN;ITPR3_HUMAN,89 (89),0.0155,1,,
Salivary secretion - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,90 (90),0.0158,1,,
NIK-->noncanonical NF-kB signaling,Reactome,1,NFKB2_HUMAN,8 (8),0.017,1,,
Dectin-1 mediated noncanonical NF-kB signaling,Reactome,1,NFKB2_HUMAN,8 (8),0.017,1,,
Transport of fatty acids,Reactome,1,S27A6_HUMAN,8 (8),0.017,1,,
Phase I biotransformations_ non P450,Wikipathways,1,PON3_HUMAN,8 (8),0.017,1,,
ApoE and miR-146 in inflammation and atherosclerosis,Wikipathways,1,NFKB2_HUMAN,8 (8),0.017,1,,
Circadian entrainment - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,96 (96),0.0179,1,,
Synthesis of 5-eicosatetraenoic acids,Reactome,1,PON3_HUMAN,9 (9),0.0191,1,,
WNT mediated activation of DVL,Reactome,1,DVL1_HUMAN,9 (9),0.0191,1,,
Neural Crest Differentiation,Wikipathways,2,NFKB2_HUMAN;DVL1_HUMAN,101 (101),0.0196,1,,
Chromatin organization,Reactome,3,ARI1B_HUMAN;KMT2B_HUMAN;NFKB2_HUMAN,271 (272),0.0197,1,,
Chromatin modifying enzymes,Reactome,3,ARI1B_HUMAN;KMT2B_HUMAN;NFKB2_HUMAN,271 (272),0.0197,1,,
C-type lectin receptor signaling pathway - Homo sapiens (human),KEGG,2,ITPR3_HUMAN;NFKB2_HUMAN,104 (104),0.0208,1,,
Signaling by WNT,Reactome,3,KGP1_HUMAN;ITPR3_HUMAN;DVL1_HUMAN,277 (278),0.0209,1,,
Cohesin Loading onto Chromatin,Reactome,1,STAG2_HUMAN,10 (10),0.0213,1,,
Gemcitabine Pathway_ Pharmacodynamics,PharmGKB,1,DCK_HUMAN,10 (10),0.0213,1,,
Thermogenesis,Wikipathways,2,KGP1_HUMAN;ARI1B_HUMAN,108 (108),0.0223,1,,
DNA Damage Response (only ATM dependent),Wikipathways,2,NFKB2_HUMAN;DVL1_HUMAN,110 (110),0.023,1,,
CLEC7A (Dectin-1) induces NFAT activation,Reactome,1,ITPR3_HUMAN,11 (11),0.0234,1,,
Pyrimidine salvage,Reactome,1,DCK_HUMAN,11 (11),0.0234,1,,
Establishment of Sister Chromatid Cohesion,Reactome,1,STAG2_HUMAN,11 (11),0.0234,1,,
SeMet incorporation into proteins,Reactome,1,SYIC_HUMAN,11 (11),0.0234,1,,
Degradation of DVL,Reactome,1,DVL1_HUMAN,12 (12),0.0255,1,,
Vascular smooth muscle contraction - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,121 (121),0.0275,1,,
DEx/H-box helicases activate type I IFN and inflammatory cytokines production ,Reactome,1,NFKB2_HUMAN,13 (13),0.0275,1,,
Purine salvage,Reactome,1,DCK_HUMAN,13 (13),0.0275,1,,
purine deoxyribonucleosides salvage,HumanCyc,1,DCK_HUMAN,13 (13),0.0275,1,,
Gemcitabine Action Pathway,SMPDB,1,DCK_HUMAN,13 (13),0.0275,1,,
Gemcitabine Metabolism Pathway,SMPDB,1,DCK_HUMAN,13 (13),0.0275,1,,
MFAP5-mediated ovarian cancer cell motility and invasiveness,Wikipathways,1,ITPR3_HUMAN,13 (13),0.0275,1,,
Platelet activation - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,123 (123),0.0284,1,,
Mitotic Telophase/Cytokinesis,Reactome,1,STAG2_HUMAN,14 (14),0.0296,1,,
GPR40 Pathway,Wikipathways,1,ITPR3_HUMAN,15 (15),0.0317,1,,
Rap1 signalling,Reactome,1,KGP1_HUMAN,16 (16),0.0338,1,,
Elevation of cytosolic Ca2+ levels,Reactome,1,ITPR3_HUMAN,16 (16),0.0338,1,,
Estrogen signaling pathway - Homo sapiens (human),KEGG,2,K1C17_HUMAN;ITPR3_HUMAN,137 (137),0.0346,1,,
superpathway of pyrimidine deoxyribonucleoside salvage,HumanCyc,1,DCK_HUMAN,17 (17),0.0359,1,,
Canonical and Non-Canonical TGF-B signaling,Wikipathways,1,GREM1_HUMAN,17 (17),0.0359,1,,
Degradation of beta catenin,PID,1,DVL1_HUMAN,18 (18),0.0379,1,,
Lamivudine Pathway_ Pharmacokinetics/Pharmacodynamics,PharmGKB,1,DCK_HUMAN,18 (18),0.0379,1,,
Lamivudine Metabolism Pathway,SMPDB,1,DCK_HUMAN,18 (18),0.0379,1,,
cGMP effects,Reactome,1,KGP1_HUMAN,18 (18),0.0379,1,,
Breast cancer - Homo sapiens (human),KEGG,2,DVL1_HUMAN;NFKB2_HUMAN,147 (147),0.0393,1,,
VEGFR2 mediated cell proliferation,Reactome,1,ITPR3_HUMAN,19 (19),0.04,1,,
Canonical Wnt signaling pathway,PID,1,DVL1_HUMAN,20 (20),0.0421,1,,
Receptor-type tyrosine-protein phosphatases,Reactome,1,LIPB2_HUMAN,20 (20),0.0421,1,,
Breast cancer pathway,Wikipathways,2,NFKB2_HUMAN;DVL1_HUMAN,154 (154),0.0428,1,,
Cushing syndrome - Homo sapiens (human),KEGG,2,ITPR3_HUMAN;DVL1_HUMAN,154 (154),0.0428,1,,
TSLP,NetPath,1,NFKB2_HUMAN,21 (21),0.0441,1,,
cGMP-PKG signaling pathway - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ITPR3_HUMAN,163 (163),0.0474,1,,
RANKL,NetPath,1,NFKB2_HUMAN,23 (23),0.0482,1,,
Nucleotide salvage,Reactome,1,DCK_HUMAN,23 (23),0.0482,1,,
RIP-mediated NFkB activation via ZBP1,Reactome,1,NFKB2_HUMAN,23 (23),0.0482,1,,
Acyl chain remodelling of PS,Reactome,1,OSBL8_HUMAN,23 (23),0.0482,1,,
EBV LMP1 signaling,Wikipathways,1,NFKB2_HUMAN,23 (23),0.0482,1,,
Hepatocellular carcinoma - Homo sapiens (human),KEGG,2,ARI1B_HUMAN;DVL1_HUMAN,167 (168),0.0495,1,,
segmentation clock,BioCarta,1,DVL1_HUMAN,24 (24),0.0503,1,,
Cytosolic tRNA aminoacylation,Reactome,1,SYIC_HUMAN,24 (24),0.0503,1,,
Nitric oxide stimulates guanylate cyclase,Reactome,1,KGP1_HUMAN,25 (25),0.0523,1,,
TRAF6 mediated NF-kB activation,Reactome,1,NFKB2_HUMAN,26 (26),0.0544,1,,
ZBP1(DAI) mediated induction of type I IFNs,Reactome,1,NFKB2_HUMAN,27 (27),0.0564,1,,
Effects of PIP2 hydrolysis,Reactome,1,ITPR3_HUMAN,27 (27),0.0564,1,,
TWEAK,NetPath,1,NFKB2_HUMAN,28 (28),0.0584,1,,
multi-step regulation of transcription by pitx2,BioCarta,1,DVL1_HUMAN,28 (28),0.0584,1,,
GPCR GroupI metabotropic glutamate receptor,INOH,1,ITPR3_HUMAN,28 (28),0.0584,1,,
Transcriptional regulation of pluripotent stem cells,Reactome,1,FOXP1_HUMAN,28 (28),0.0584,1,,
Platelet calcium homeostasis,Reactome,1,ITPR3_HUMAN,28 (28),0.0584,1,,
Disassembly of the destruction complex and recruitment of AXIN to the membrane,Reactome,1,DVL1_HUMAN,29 (29),0.0604,1,,
Interaction between L1 and Ankyrins,Reactome,1,SPTB1_HUMAN,29 (29),0.0604,1,,
VEGF,INOH,2,KGP1_HUMAN;ITPR3_HUMAN,188 (188),0.061,1,,
Regulation of p38-alpha and p38-beta,PID,1,KGP1_HUMAN,31 (31),0.0645,1,,
wnt signaling pathway,BioCarta,1,DVL1_HUMAN,31 (31),0.0645,1,,
Toll-like Receptor Signaling,Wikipathways,1,NFKB2_HUMAN,31 (31),0.0645,1,,
Tumor suppressor activity of SMARCB1,Wikipathways,1,ARI1B_HUMAN,31 (31),0.0645,1,,
Peptide ligand-binding receptors,Reactome,2,KELL_HUMAN;PENK_HUMAN,194 (194),0.0645,1,,
Transcriptional regulation by RUNX1,Reactome,2,ARI1B_HUMAN;KMT2B_HUMAN,196 (198),0.0657,1,,
Noncanonical Wnt signaling pathway,PID,1,DVL1_HUMAN,32 (32),0.0665,1,,
TAK1 activates NFkB by phosphorylation and activation of IKKs complex,Reactome,1,NFKB2_HUMAN,32 (32),0.0665,1,,
DAG and IP3 signaling,Reactome,1,ITPR3_HUMAN,32 (32),0.0665,1,,
Photodynamic therapy-induced NF-kB survival signaling,Wikipathways,1,NFKB2_HUMAN,35 (35),0.0725,1,,
miRNAs involvement in the immune response in sepsis,Wikipathways,1,NFKB2_HUMAN,36 (64),0.0745,1,,
Wnt Signaling in Kidney Disease,Wikipathways,1,DVL1_HUMAN,36 (37),0.0745,1,,
G13 Signaling Pathway,Wikipathways,1,ACK1_HUMAN,38 (38),0.0785,1,,
tRNA charging,HumanCyc,1,SYIC_HUMAN,38 (38),0.0785,1,,
Intracellular Signalling Through Adenosine Receptor A2b and Adenosine,SMPDB,1,NFKB2_HUMAN,38 (38),0.0785,1,,
Intracellular Signalling Through Adenosine Receptor A2a and Adenosine,SMPDB,1,NFKB2_HUMAN,38 (38),0.0785,1,,
Transport of vitamins_ nucleosides_ and related molecules,Reactome,1,S27A6_HUMAN,39 (39),0.0805,1,,
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known,Reactome,1,ARI1B_HUMAN,39 (40),0.0805,1,,
O-glycosylation of TSR domain-containing proteins,Reactome,1,ATS5_HUMAN,39 (39),0.0805,1,,
inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages,BioCarta,1,DVL1_HUMAN,40 (40),0.0824,1,,
Oxidative Damage,Wikipathways,1,ACK1_HUMAN,40 (40),0.0824,1,,
BMP receptor signaling,PID,1,GREM1_HUMAN,41 (41),0.0844,1,,
TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,41 (41),0.0844,1,,
Thermogenesis - Homo sapiens (human),KEGG,2,KGP1_HUMAN;ARI1B_HUMAN,229 (229),0.086,1,,
tRNA Aminoacylation,Reactome,1,SYIC_HUMAN,42 (42),0.0864,1,,
CD4 T cell receptor signaling-ERK cascade,INOH,1,ITPR3_HUMAN,42 (42),0.0864,1,,
actions of nitric oxide in the heart,BioCarta,1,KGP1_HUMAN,42 (42),0.0864,1,,
Hair Follicle Development- Induction (Part 1 of 3),Wikipathways,1,DVL1_HUMAN,42 (42),0.0864,1,,
PLK1 signaling events,PID,1,STAG2_HUMAN,44 (44),0.0903,1,,
Aminoacyl-tRNA biosynthesis - Homo sapiens (human),KEGG,1,SYIC_HUMAN,44 (66),0.0903,1,,
PLC beta mediated events,Reactome,1,ITPR3_HUMAN,44 (44),0.0903,1,,
Tacrolimus/Cyclosporine Pathway_ Pharmacodynamics,PharmGKB,1,NFKB2_HUMAN,44 (44),0.0903,1,,
WNT-Core,Signalink,1,DVL1_HUMAN,44 (44),0.0903,1,,
G-protein mediated events,Reactome,1,ITPR3_HUMAN,45 (45),0.0923,1,,
Notch Signaling,Wikipathways,1,DVL1_HUMAN,45 (45),0.0923,1,,
Intra-Golgi traffic,Reactome,1,GOGA5_HUMAN,45 (45),0.0923,1,,
Presenilin action in Notch and Wnt signaling,PID,1,DVL1_HUMAN,46 (46),0.0942,1,,
Regulation of Microtubule Cytoskeleton,Wikipathways,1,DVL1_HUMAN,46 (46),0.0942,1,,
ion channels and their functional role in vascular endothelium,BioCarta,1,KGP1_HUMAN,47 (47),0.0962,1,,
Meiotic synapsis,Reactome,1,STAG2_HUMAN,47 (47),0.0962,1,,
PCP/CE pathway,Reactome,1,DVL1_HUMAN,47 (47),0.0962,1,,
Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,47 (47),0.0962,1,,
agrin in postsynaptic differentiation,BioCarta,1,DVL1_HUMAN,48 (48),0.0981,1,,
Notch signaling pathway - Homo sapiens (human),KEGG,1,DVL1_HUMAN,48 (48),0.0981,1,,
TNFR2 non-canonical NF-kB pathway,Reactome,1,NFKB2_HUMAN,50 (50),0.102,1,,
Vitamin B12 Metabolism,Wikipathways,1,NFKB2_HUMAN,50 (51),0.102,1,,
Protein alkylation leading to liver fibrosis,Wikipathways,1,NFKB2_HUMAN,50 (50),0.102,1,,
Cytosolic sensors of pathogen-associated DNA ,Reactome,1,NFKB2_HUMAN,51 (51),0.104,1,,
Wnt Signaling Pathway,Wikipathways,1,DVL1_HUMAN,51 (51),0.104,1,,
Pyrimidine nucleotides nucleosides metabolism,INOH,1,DCK_HUMAN,51 (51),0.104,1,,
Ion homeostasis,Reactome,1,ITPR3_HUMAN,52 (52),0.106,1,,
Regulation of lipolysis in adipocytes - Homo sapiens (human),KEGG,1,KGP1_HUMAN,54 (54),0.11,1,,
Cardiac Hypertrophic Response,Wikipathways,1,KGP1_HUMAN,54 (54),0.11,1,,
CD4 T cell receptor signaling-JNK cascade,INOH,1,ITPR3_HUMAN,55 (55),0.112,1,,
Legionellosis - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,55 (55),0.112,1,,
RANKL-RANK (Receptor activator of NFKB (ligand)) Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,55 (55),0.112,1,,
DDX58/IFIH1-mediated induction of interferon-alpha/beta,Reactome,1,NFKB2_HUMAN,56 (56),0.114,1,,
Thromboxane A2 receptor signaling,PID,1,KGP1_HUMAN,56 (57),0.114,1,,
NCAM signaling for neurite out-growth,Reactome,1,SPTB1_HUMAN,59 (59),0.119,1,,
Lysine degradation - Homo sapiens (human),KEGG,1,KMT2B_HUMAN,59 (59),0.119,1,,
Interleukin-1 signaling,Reactome,1,NFKB2_HUMAN,60 (60),0.121,1,,
Arachidonic acid metabolism,Reactome,1,PON3_HUMAN,61 (62),0.123,1,,
Endochondral Ossification,Wikipathways,1,ATS5_HUMAN,63 (63),0.127,1,,
IL12-mediated signaling events,PID,1,NFKB2_HUMAN,63 (65),0.127,1,,
Basal cell carcinoma - Homo sapiens (human),KEGG,1,DVL1_HUMAN,63 (63),0.127,1,,
Cortisol synthesis and secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,64 (64),0.129,1,,
Association Between Physico-Chemical Features and Toxicity Associated Pathways,Wikipathways,1,DVL1_HUMAN,64 (65),0.129,1,,
Extracellular matrix organization,Reactome,2,ATS5_HUMAN;P3H2_HUMAN,293 (294),0.13,1,,
Folate Metabolism,Wikipathways,1,NFKB2_HUMAN,65 (66),0.131,1,,
Renin secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,65 (65),0.131,1,,
Histone Modifications,Wikipathways,1,KMT2B_HUMAN,66 (66),0.132,1,,
Long-term potentiation - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,67 (67),0.134,1,,
EGFR Inhibitor Pathway_ Pharmacodynamics,PharmGKB,1,NFKB2_HUMAN,67 (67),0.134,1,,
Non-genomic actions of 1_25 dihydroxyvitamin D3,Wikipathways,1,NFKB2_HUMAN,68 (68),0.136,1,,
Collagen biosynthesis and modifying enzymes,Reactome,1,P3H2_HUMAN,68 (68),0.136,1,,
Wnt,NetPath,1,DVL1_HUMAN,68 (69),0.136,1,,
PPAR signaling pathway,Wikipathways,1,S27A6_HUMAN,68 (68),0.136,1,,
AP-1 transcription factor network,PID,1,PENK_HUMAN,70 (70),0.14,1,,
Regulation of insulin secretion,Reactome,1,ITPR3_HUMAN,70 (70),0.14,1,,
Glucocorticoid Receptor Pathway,Wikipathways,1,NFKB2_HUMAN,70 (71),0.14,1,,
CDC42 signaling events,PID,1,ACK1_HUMAN,71 (71),0.142,1,,
Androgen Receptor Network in Prostate Cancer,Wikipathways,1,ARI1B_HUMAN,71 (72),0.142,1,,
Developmental Biology,Reactome,3,K1C17_HUMAN;SPTB1_HUMAN;FOXP1_HUMAN,618 (620),0.145,1,,
RMTs methylate histone arginines,Reactome,1,ARI1B_HUMAN,74 (74),0.147,1,,
PPAR signaling pathway - Homo sapiens (human),KEGG,1,S27A6_HUMAN,74 (74),0.147,1,,
Thyroid hormone synthesis - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,74 (74),0.147,1,,
Gastric acid secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,75 (75),0.149,1,,
Viral Acute Myocarditis,Wikipathways,1,NFKB2_HUMAN,76 (76),0.151,1,,
SUMOylation of DNA damage response and repair proteins,Reactome,1,STAG2_HUMAN,76 (76),0.151,1,,
Interleukin-1 family signaling,Reactome,1,NFKB2_HUMAN,77 (77),0.153,1,,
Meiosis,Reactome,1,STAG2_HUMAN,78 (78),0.155,1,,
Alzheimers Disease,Wikipathways,1,ITPR3_HUMAN,79 (145),0.157,1,,
Class A/1 (Rhodopsin-like receptors),Reactome,2,KELL_HUMAN;PENK_HUMAN,330 (330),0.157,1,,
Glucocorticoid receptor regulatory network,PID,1,K1C17_HUMAN,80 (80),0.158,1,,
Opioid Signalling,Reactome,1,ITPR3_HUMAN,81 (82),0.16,1,,
Selenium Micronutrient Network,Wikipathways,1,NFKB2_HUMAN,82 (83),0.162,1,,
Taste transduction - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,83 (83),0.164,1,,
COPI-mediated anterograde transport,Reactome,1,SPTB1_HUMAN,83 (83),0.164,1,,
ncRNAs involved in Wnt signaling in hepatocellular carcinoma,Wikipathways,1,DVL1_HUMAN,84 (86),0.166,1,,
Pyrimidine metabolism,Wikipathways,1,DCK_HUMAN,84 (84),0.166,1,,
Post-translational protein modification,Reactome,5,ATS5_HUMAN;PENK_HUMAN;SPTB1_HUMAN;UBP24_HUMAN;STAG2_HUMAN,1377 (1383),0.166,1,,
Insulin secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,85 (85),0.167,1,,
MyD88 cascade initiated on plasma membrane,Reactome,1,NFKB2_HUMAN,87 (87),0.171,1,,
Toll Like Receptor 10 (TLR10) Cascade,Reactome,1,NFKB2_HUMAN,87 (87),0.171,1,,
Toll Like Receptor 5 (TLR5) Cascade,Reactome,1,NFKB2_HUMAN,87 (87),0.171,1,,
Retinoblastoma Gene in Cancer,Wikipathways,1,DCK_HUMAN,87 (89),0.171,1,,
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,Reactome,1,NFKB2_HUMAN,88 (88),0.173,1,,
Protein-protein interactions at synapses,Reactome,1,LIPB2_HUMAN,88 (88),0.173,1,,
Toll Like Receptor 7/8 (TLR7/8) Cascade,Reactome,1,NFKB2_HUMAN,90 (90),0.176,1,,
MyD88 dependent cascade initiated on endosome,Reactome,1,NFKB2_HUMAN,90 (90),0.176,1,,
Amino Acid metabolism,Wikipathways,1,SYIC_HUMAN,91 (91),0.178,1,,
VEGFA-VEGFR2 Pathway,Reactome,1,ITPR3_HUMAN,92 (92),0.18,1,,
Collagen formation,Reactome,1,P3H2_HUMAN,92 (92),0.18,1,,
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function,Reactome,1,KMT2B_HUMAN,92 (94),0.18,1,,
TNF alpha Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,92 (93),0.18,1,,
LncRNA involvement in canonical Wnt signaling and colorectal cancer,Wikipathways,1,DVL1_HUMAN,93 (97),0.182,1,,
GnRH signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,93 (93),0.182,1,,
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers,Reactome,1,ITPR3_HUMAN,94 (97),0.183,1,,
Toll Like Receptor 9 (TLR9) Cascade,Reactome,1,NFKB2_HUMAN,94 (94),0.183,1,,
Integration of energy metabolism,Reactome,1,ITPR3_HUMAN,94 (94),0.183,1,,
NF-kappa B signaling pathway - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,94 (95),0.183,1,,
Aldosterone synthesis and secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,96 (96),0.187,1,,
Pancreatic secretion - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,96 (96),0.187,1,,
Toll Like Receptor 3 (TLR3) Cascade,Reactome,1,NFKB2_HUMAN,97 (97),0.189,1,,
CD4 T cell receptor signaling-NFkB cascade,INOH,1,ITPR3_HUMAN,97 (97),0.189,1,,
MyD88:Mal cascade initiated on plasma membrane,Reactome,1,NFKB2_HUMAN,97 (97),0.189,1,,
Toll Like Receptor TLR1:TLR2 Cascade,Reactome,1,NFKB2_HUMAN,97 (97),0.189,1,,
Toll Like Receptor TLR6:TLR2 Cascade,Reactome,1,NFKB2_HUMAN,97 (97),0.189,1,,
Toll Like Receptor 2 (TLR2) Cascade,Reactome,1,NFKB2_HUMAN,97 (97),0.189,1,,
Phosphatidylinositol signaling system - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,99 (99),0.192,1,,
Inflammatory mediator regulation of TRP channels - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,99 (99),0.192,1,,
Signaling by VEGF,Reactome,1,ITPR3_HUMAN,100 (100),0.194,1,,
Wnt Signaling Pathway and Pluripotency,Wikipathways,1,DVL1_HUMAN,101 (101),0.196,1,,
Melanogenesis - Homo sapiens (human),KEGG,1,DVL1_HUMAN,101 (101),0.196,1,,
Pyrimidine metabolism - Homo sapiens (human),KEGG,1,DCK_HUMAN,101 (101),0.196,1,,
L1CAM interactions,Reactome,1,SPTB1_HUMAN,101 (103),0.196,1,,
TRIF(TICAM1)-mediated TLR4 signaling ,Reactome,1,NFKB2_HUMAN,101 (101),0.196,1,,
MyD88-independent TLR4 cascade ,Reactome,1,NFKB2_HUMAN,101 (101),0.196,1,,
Toll-like Receptor Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,102 (102),0.197,1,,
S Phase,Reactome,1,STAG2_HUMAN,102 (103),0.197,1,,
Role of phospholipids in phagocytosis,Reactome,1,ITPR3_HUMAN,103 (108),0.199,1,,
FCERI mediated Ca+2 mobilization,Reactome,1,ITPR3_HUMAN,103 (108),0.199,1,,
Glucagon signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,103 (103),0.199,1,,
Reproduction,Reactome,1,STAG2_HUMAN,104 (104),0.201,1,,
Metabolism of nucleotides,Reactome,1,DCK_HUMAN,105 (105),0.203,1,,
Degradation of the extracellular matrix,Reactome,1,ATS5_HUMAN,105 (105),0.203,1,,
Parathyroid hormone synthesis_ secretion and action - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,106 (106),0.204,1,,
Insulin resistance - Homo sapiens (human),KEGG,1,S27A6_HUMAN,107 (107),0.206,1,,
Post-translational protein phosphorylation,Reactome,1,PENK_HUMAN,108 (110),0.208,1,,
Resolution of Sister Chromatid Cohesion,Reactome,1,STAG2_HUMAN,109 (109),0.21,1,,
G alpha (i) signalling events,Reactome,2,PENK_HUMAN;ITPR3_HUMAN,399 (400),0.211,1,,
Cholinergic synapse - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,112 (112),0.215,1,,
Wnt Signaling,Wikipathways,1,DVL1_HUMAN,114 (114),0.218,1,,
Glutamatergic synapse - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,114 (114),0.218,1,,
Serotonergic synapse - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,115 (115),0.22,1,,
O-linked glycosylation,Reactome,1,ATS5_HUMAN,116 (116),0.221,1,,
ESC Pluripotency Pathways,Wikipathways,1,DVL1_HUMAN,116 (116),0.221,1,,
Wnt Canonical,INOH,1,DVL1_HUMAN,119 (119),0.226,1,,
Wnt Mammals,INOH,1,DVL1_HUMAN,119 (119),0.226,1,,
SUMO E3 ligases SUMOylate target proteins,Reactome,1,STAG2_HUMAN,120 (120),0.228,1,,
Cell Cycle,Wikipathways,1,STAG2_HUMAN,120 (120),0.228,1,,
Selenoamino acid metabolism,Reactome,1,SYIC_HUMAN,121 (130),0.23,1,,
RHO GTPases Activate Formins,Reactome,1,DVL1_HUMAN,123 (123),0.233,1,,
Oocyte meiosis - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,123 (125),0.233,1,,
Signaling by the B Cell Receptor (BCR),Reactome,1,ITPR3_HUMAN,124 (127),0.235,1,,
Cell cycle - Homo sapiens (human),KEGG,1,STAG2_HUMAN,124 (124),0.235,1,,
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs),Reactome,1,PENK_HUMAN,125 (127),0.236,1,,
SUMOylation,Reactome,1,STAG2_HUMAN,126 (126),0.238,1,,
Toll Like Receptor 4 (TLR4) Cascade,Reactome,1,NFKB2_HUMAN,127 (127),0.24,1,,
Osteoclast differentiation - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,128 (128),0.241,1,,
Separation of Sister Chromatids,Reactome,1,STAG2_HUMAN,128 (129),0.241,1,,
Keratinization,Reactome,1,K1C17_HUMAN,129 (129),0.243,1,,
CD4 T cell receptor signaling,INOH,1,ITPR3_HUMAN,130 (130),0.245,1,,
Adipogenesis,Wikipathways,1,DVL1_HUMAN,130 (131),0.245,1,,
Ebola Virus Pathway on Host,Wikipathways,1,NFKB2_HUMAN,130 (130),0.245,1,,
Cardiac conduction,Reactome,1,ITPR3_HUMAN,131 (131),0.246,1,,
Dopaminergic synapse - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,131 (131),0.246,1,,
Metabolism of proteins,Reactome,6,STAG2_HUMAN;SYIC_HUMAN;SPTB1_HUMAN;ATS5_HUMAN;PENK_HUMAN;UBP24_HUMAN,1991 (2008),0.247,1,,
Glycerophospholipid biosynthesis,Reactome,1,OSBL8_HUMAN,132 (133),0.248,1,,
B cell receptor signaling,INOH,1,ITPR3_HUMAN,134 (134),0.251,1,,
Apoptosis - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,136 (136),0.254,1,,
Pyrimidine metabolism,EHMN,1,DCK_HUMAN,136 (136),0.254,1,,
EGFR1,NetPath,2,K1C17_HUMAN;ACK1_HUMAN,455 (457),0.255,1,,
Apelin signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,137 (137),0.256,1,,
ER to Golgi Anterograde Transport,Reactome,1,SPTB1_HUMAN,137 (137),0.256,1,,
Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human),KEGG,1,DVL1_HUMAN,139 (139),0.259,1,,
Ectoderm Differentiation,Wikipathways,1,LIPB2_HUMAN,139 (142),0.259,1,,
Mitotic Anaphase,Reactome,1,STAG2_HUMAN,139 (140),0.259,1,,
Regulation of toll-like receptor signaling pathway,Wikipathways,1,NFKB2_HUMAN,139 (143),0.259,1,,
Mitotic Metaphase and Anaphase,Reactome,1,STAG2_HUMAN,140 (141),0.261,1,,
Estrogen-dependent gene expression,Reactome,1,STAG2_HUMAN,141 (142),0.263,1,,
GPCR ligand binding,Reactome,2,KELL_HUMAN;PENK_HUMAN,465 (466),0.263,1,,
Fc epsilon receptor (FCERI) signaling,Reactome,1,ITPR3_HUMAN,145 (150),0.269,1,,
Retrograde endocannabinoid signaling - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,148 (148),0.274,1,,
Gastric cancer - Homo sapiens (human),KEGG,1,DVL1_HUMAN,148 (149),0.274,1,,
Calcium Regulation in the Cardiac Cell,Wikipathways,1,ITPR3_HUMAN,149 (149),0.275,1,,
Wnt signaling pathway - Homo sapiens (human),KEGG,1,DVL1_HUMAN,149 (149),0.275,1,,
ESR-mediated signaling,Reactome,1,STAG2_HUMAN,149 (150),0.275,1,,
MicroRNAs in cancer - Homo sapiens (human),KEGG,1,FOXP1_HUMAN,150 (299),0.277,1,,
mTOR signaling pathway - Homo sapiens (human),KEGG,1,DVL1_HUMAN,151 (151),0.278,1,,
Oxytocin signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,152 (152),0.28,1,,
Toll-Like Receptors Cascades,Reactome,1,NFKB2_HUMAN,154 (154),0.283,1,,
Fcgamma receptor (FCGR) dependent phagocytosis,Reactome,1,ITPR3_HUMAN,154 (159),0.283,1,,
Hippo signaling pathway - Homo sapiens (human),KEGG,1,DVL1_HUMAN,154 (154),0.283,1,,
Myometrial Relaxation and Contraction Pathways,Wikipathways,1,ITPR3_HUMAN,155 (155),0.285,1,,
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways,Wikipathways,1,NFKB2_HUMAN,156 (159),0.286,1,,
Cellular senescence - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,160 (160),0.292,1,,
EGF-EGFR Signaling Pathway,Wikipathways,1,ACK1_HUMAN,162 (162),0.295,1,,
NOD-like receptor signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,168 (168),0.305,1,,
Transport to the Golgi and subsequent modification,Reactome,1,SPTB1_HUMAN,168 (168),0.305,1,,
Alzheimer disease - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,171 (171),0.309,1,,
Pathways in cancer - Homo sapiens (human),KEGG,2,DVL1_HUMAN;NFKB2_HUMAN,525 (526),0.312,1,,
Purine metabolism - Homo sapiens (human),KEGG,1,DCK_HUMAN,173 (174),0.312,1,,
Vitamin D Receptor Pathway,Wikipathways,1,ATS5_HUMAN,182 (184),0.325,1,,
Calcium signaling pathway - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,185 (186),0.33,1,,
IL-7 signaling,INOH,1,KGP1_HUMAN,185 (185),0.33,1,,
Signal Transduction,Reactome,7,STAG2_HUMAN;KELL_HUMAN;SPTB1_HUMAN;KGP1_HUMAN;PENK_HUMAN;ITPR3_HUMAN;DVL1_HUMAN,2634 (2647),0.33,1,,
Mitotic Prometaphase,Reactome,1,STAG2_HUMAN,186 (186),0.331,1,,
EPO signaling,INOH,1,KGP1_HUMAN,186 (186),0.331,1,,
Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,186 (186),0.331,1,,
Intra-Golgi and retrograde Golgi-to-ER traffic,Reactome,1,GOGA5_HUMAN,186 (186),0.331,1,,
Fatty acid metabolism,Reactome,1,PON3_HUMAN,187 (189),0.333,1,,
TCF dependent signaling in response to WNT,Reactome,1,DVL1_HUMAN,189 (190),0.336,1,,
Signaling by Nuclear Receptors,Reactome,1,STAG2_HUMAN,194 (195),0.343,1,,
Muscle contraction,Reactome,1,ITPR3_HUMAN,195 (195),0.344,1,,
RAF/MAP kinase cascade,Reactome,1,SPTB1_HUMAN,196 (197),0.346,1,,
Proteoglycans in cancer - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,198 (201),0.349,1,,
Focal Adhesion,Wikipathways,1,ACK1_HUMAN,198 (198),0.349,1,,
Epstein-Barr virus infection - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,200 (201),0.351,1,,
Viral carcinogenesis - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,201 (201),0.353,1,,
MAPK1/MAPK3 signaling,Reactome,1,SPTB1_HUMAN,202 (203),0.354,1,,
Membrane Trafficking,Reactome,2,SPTB1_HUMAN;GOGA5_HUMAN,582 (582),0.357,1,,
Human immunodeficiency virus 1 infection - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,212 (212),0.368,1,,
G alpha (q) signalling events,Reactome,1,ITPR3_HUMAN,213 (213),0.37,1,,
Phospholipid metabolism,Reactome,1,OSBL8_HUMAN,215 (216),0.372,1,,
Human T-cell leukemia virus 1 infection - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,219 (219),0.378,1,,
Ub-specific processing proteases,Reactome,1,UBP24_HUMAN,220 (220),0.379,1,,
Purine metabolism,EHMN,1,DCK_HUMAN,223 (223),0.383,1,,
Human cytomegalovirus infection - Homo sapiens (human),KEGG,1,ITPR3_HUMAN,225 (225),0.386,1,,
Vesicle-mediated transport,Reactome,2,SPTB1_HUMAN;GOGA5_HUMAN,620 (620),0.387,1,,
TNFalpha,NetPath,1,NFKB2_HUMAN,234 (234),0.398,1,,
MAPK family signaling cascades,Reactome,1,SPTB1_HUMAN,234 (237),0.398,1,,
VEGFA-VEGFR2 Signaling Pathway,Wikipathways,1,KGP1_HUMAN,236 (236),0.4,1,,
TCR,NetPath,1,GOGA5_HUMAN,241 (245),0.407,1,,
SLC-mediated transmembrane transport,Reactome,1,S27A6_HUMAN,244 (245),0.411,1,,
Metabolism,Reactome,5,SYIC_HUMAN;DCK_HUMAN;OSBL8_HUMAN;PON3_HUMAN;ITPR3_HUMAN,1954 (1972),0.411,1,,
Intracellular signaling by second messengers,Reactome,1,ITPR3_HUMAN,245 (245),0.412,1,,
MAPK Signaling Pathway,Wikipathways,1,NFKB2_HUMAN,246 (246),0.413,1,,
Metabolism of lipids,Reactome,2,OSBL8_HUMAN;PON3_HUMAN,660 (664),0.418,1,,
Hemostasis,Reactome,2,KGP1_HUMAN;ITPR3_HUMAN,662 (668),0.419,1,,
Signaling by Interleukins,Reactome,1,NFKB2_HUMAN,254 (254),0.424,1,,
Generic Transcription Pathway,Reactome,3,ZNF28_HUMAN;ARI1B_HUMAN;KMT2B_HUMAN,1101 (1107),0.425,1,,
Platelet activation_ signaling and aggregation,Reactome,1,ITPR3_HUMAN,259 (260),0.43,1,,
GPCR signaling-G alpha q,INOH,1,ITPR3_HUMAN,274 (274),0.448,1,,
Asparagine N-linked glycosylation,Reactome,1,SPTB1_HUMAN,286 (286),0.463,1,,
Adaptive Immune System,Reactome,2,KGP1_HUMAN;ITPR3_HUMAN,722 (732),0.464,1,,
MAPK signaling pathway - Homo sapiens (human),KEGG,1,NFKB2_HUMAN,295 (295),0.473,1,,
Deubiquitination,Reactome,1,UBP24_HUMAN,296 (296),0.474,1,,
Translation,Reactome,1,SYIC_HUMAN,299 (310),0.478,1,,
RHO GTPase Effectors,Reactome,1,DVL1_HUMAN,301 (301),0.48,1,,
JAK STAT pathway and regulation,INOH,1,KGP1_HUMAN,310 (310),0.49,1,,
RNA Polymerase II Transcription,Reactome,3,ZNF28_HUMAN;ARI1B_HUMAN;KMT2B_HUMAN,1223 (1236),0.496,1,,
Nuclear Receptors Meta-Pathway,Wikipathways,1,NFKB2_HUMAN,315 (316),0.496,1,,
Signaling by GPCR,Reactome,3,KELL_HUMAN;PENK_HUMAN;ITPR3_HUMAN,1235 (1240),0.502,1,,
Metabolism of amino acids and derivatives,Reactome,1,SYIC_HUMAN,330 (342),0.512,1,,
M Phase,Reactome,1,STAG2_HUMAN,338 (340),0.521,1,,
Human papillomavirus infection - Homo sapiens (human),KEGG,1,DVL1_HUMAN,339 (339),0.522,1,,
Axon guidance,Reactome,1,SPTB1_HUMAN,356 (358),0.54,1,,
Neuronal System,Reactome,1,LIPB2_HUMAN,368 (368),0.552,1,,
Gene expression (Transcription),Reactome,3,ZNF28_HUMAN;ARI1B_HUMAN;KMT2B_HUMAN,1360 (1373),0.57,1,,
Signaling by Receptor Tyrosine Kinases,Reactome,1,ITPR3_HUMAN,423 (423),0.603,1,,
Signaling by Rho GTPases,Reactome,1,DVL1_HUMAN,431 (435),0.61,1,,
Olfactory transduction - Homo sapiens (human),KEGG,1,KGP1_HUMAN,446 (447),0.623,1,,
Cytokine Signaling in Immune system,Reactome,1,NFKB2_HUMAN,458 (458),0.633,1,,
Cell Cycle_ Mitotic,Reactome,1,STAG2_HUMAN,479 (481),0.65,1,,
Innate Immune System,Reactome,2,ITPR3_HUMAN;NFKB2_HUMAN,1067 (1077),0.68,1,,
Cell Cycle,Reactome,1,STAG2_HUMAN,562 (564),0.709,1,,
Metabolism of RNA,Reactome,1,IF2B2_HUMAN,577 (586),0.719,1,,
GPCR downstream signalling,Reactome,2,PENK_HUMAN;ITPR3_HUMAN,1172 (1176),0.731,1,,
Transport of small molecules,Reactome,1,S27A6_HUMAN,665 (666),0.769,1,,
Immune System,Reactome,3,KGP1_HUMAN;ITPR3_HUMAN;NFKB2_HUMAN,1825 (1840),0.772,1,,