pathway_name,pathway_source,num_overlapping_genes,overlapping_genes,num_all_pathway_genes,P_genes,Q_genes,, Purine metabolism - Homo sapiens (human),KEGG,2,ADCY6_HUMAN;RPA1_HUMAN,173 (174),0.00183,1,0.000543478,92 Glycerophospholipid catabolism,Reactome,1,PLPL6_HUMAN,7 (7),0.00278,1,, Inactivation of CDC42 and RAC1,Reactome,1,SRGP3_HUMAN,8 (8),0.00317,1,, Adenylate cyclase activating pathway,Reactome,1,ADCY6_HUMAN,10 (10),0.00397,1,, Nucleotide Excision Repair ,SMPDB,1,RPA1_HUMAN,11 (11),0.00436,1,, Adenylate cyclase inhibitory pathway,Reactome,1,ADCY6_HUMAN,14 (14),0.00555,1,, Inhibition of adenylate cyclase pathway,Reactome,1,ADCY6_HUMAN,14 (14),0.00555,1,, LPA4-mediated signaling events,PID,1,ADCY6_HUMAN,16 (16),0.00634,1,, PKA activation,Reactome,1,ADCY6_HUMAN,17 (17),0.00674,1,, PKA activation in glucagon signalling,Reactome,1,ADCY6_HUMAN,17 (17),0.00674,1,, PKA-mediated phosphorylation of CREB,Reactome,1,ADCY6_HUMAN,18 (18),0.00713,1,, Adrenaline_noradrenaline inhibits insulin secretion,Reactome,1,ADCY6_HUMAN,23 (23),0.00911,1,, tumor suppressor arf inhibits ribosomal biogenesis,BioCarta,1,RPA1_HUMAN,23 (24),0.00911,1,, Calmodulin induced events,Reactome,1,ADCY6_HUMAN,26 (26),0.0103,1,, CaM pathway,Reactome,1,ADCY6_HUMAN,26 (26),0.0103,1,, Ca-dependent events,Reactome,1,ADCY6_HUMAN,28 (28),0.0111,1,, Peroxisomal lipid metabolism,Reactome,1,ACBD5_HUMAN,29 (29),0.0115,1,, RNA Polymerase I Promoter Escape,Reactome,1,RPA1_HUMAN,30 (30),0.0119,1,, RNA Polymerase I Transcription Termination,Reactome,1,RPA1_HUMAN,31 (31),0.0123,1,, RNA polymerase - Homo sapiens (human),KEGG,1,RPA1_HUMAN,31 (31),0.0123,1,, DAG and IP3 signaling,Reactome,1,ADCY6_HUMAN,32 (32),0.0127,1,, Glucagon signaling in metabolic regulation,Reactome,1,ADCY6_HUMAN,33 (33),0.013,1,, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion,Reactome,1,ADCY6_HUMAN,35 (35),0.0138,1,, GPCR Adenosine A2A receptor,INOH,1,ADCY6_HUMAN,36 (36),0.0142,1,, Activation of GABAB receptors,Reactome,1,ADCY6_HUMAN,39 (39),0.0154,1,, GABA B receptor activation,Reactome,1,ADCY6_HUMAN,39 (39),0.0154,1,, Vasopressin regulates renal water homeostasis via Aquaporins,Reactome,1,ADCY6_HUMAN,40 (40),0.0158,1,, Eukaryotic Transcription Initiation,Wikipathways,1,RPA1_HUMAN,41 (41),0.0162,1,, Hedgehog _off_ state,Reactome,1,ADCY6_HUMAN,43 (44),0.017,1,, PLC beta mediated events,Reactome,1,ADCY6_HUMAN,44 (44),0.0174,1,, Vasopressin-regulated water reabsorption - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,44 (44),0.0174,1,, G-protein mediated events,Reactome,1,ADCY6_HUMAN,45 (45),0.0178,1,, Proton Pump Inhibitor Pathway_ Pharmacodynamics,PharmGKB,1,ADCY6_HUMAN,46 (46),0.0181,1,, Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,47 (47),0.0185,1,, G alpha (z) signalling events,Reactome,1,ADCY6_HUMAN,47 (47),0.0185,1,, RNA Polymerase I Transcription Initiation,Reactome,1,RPA1_HUMAN,48 (48),0.0189,1,, Ovarian steroidogenesis - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,49 (49),0.0193,1,, Aquaporin-mediated transport,Reactome,1,ADCY6_HUMAN,49 (49),0.0193,1,, Phosphodiesterases in neuronal function,Wikipathways,1,ADCY6_HUMAN,52 (52),0.0205,1,, Regulation of lipolysis in adipocytes - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,54 (54),0.0213,1,, GABA receptor activation,Reactome,1,ADCY6_HUMAN,55 (55),0.0217,1,, Longevity regulating pathway - multiple species - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,62 (62),0.0244,1,, Metabolism of lipids,Reactome,2,ACBD5_HUMAN;PLPL6_HUMAN,660 (664),0.0247,1,, LPA receptor mediated events,PID,1,ADCY6_HUMAN,63 (64),0.0248,1,, Endothelins,PID,1,ADCY6_HUMAN,64 (64),0.0252,1,, Cortisol synthesis and secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,64 (64),0.0252,1,, Renin secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,65 (65),0.0256,1,, Beta-agonist/Beta-blocker Pathway_ Pharmacodynamics,PharmGKB,1,ADCY6_HUMAN,65 (66),0.0256,1,, Signaling by ROBO receptors,Reactome,1,SRGP3_HUMAN,66 (66),0.026,1,, Regulation of insulin secretion,Reactome,1,ADCY6_HUMAN,70 (70),0.0275,1,, Bile secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,71 (71),0.0279,1,, Thyroid hormone synthesis - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,74 (74),0.0291,1,, Metabolism,Reactome,3,ADCY6_HUMAN;PLPL6_HUMAN;ACBD5_HUMAN,1954 (1972),0.0292,1,, Gastric acid secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,75 (75),0.0294,1,, Signaling by Hedgehog,Reactome,1,ADCY6_HUMAN,81 (82),0.0318,1,, Opioid Signalling,Reactome,1,ADCY6_HUMAN,81 (82),0.0318,1,, Taste transduction - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,83 (83),0.0325,1,, PI Metabolism,Reactome,1,PLPL6_HUMAN,84 (84),0.0329,1,, Pyrimidine metabolism,Wikipathways,1,RPA1_HUMAN,84 (84),0.0329,1,, Insulin secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,85 (85),0.0333,1,, GABAergic synapse - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,88 (88),0.0345,1,, Gap junction - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,88 (88),0.0345,1,, Longevity regulating pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,89 (89),0.0349,1,, Dilated cardiomyopathy (DCM) - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,89 (90),0.0349,1,, Salivary secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,90 (90),0.0353,1,, Morphine addiction - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,91 (91),0.0356,1,, RNA Polymerase I Chain Elongation,Reactome,1,RPA1_HUMAN,92 (92),0.036,1,, G Protein Signaling Pathways,Wikipathways,1,ADCY6_HUMAN,92 (92),0.036,1,, GnRH signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,93 (93),0.0364,1,, B-WICH complex positively regulates rRNA expression,Reactome,1,RPA1_HUMAN,94 (94),0.0368,1,, Integration of energy metabolism,Reactome,1,ADCY6_HUMAN,94 (94),0.0368,1,, Aldosterone synthesis and secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,96 (96),0.0376,1,, Circadian entrainment - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,96 (96),0.0376,1,, Pancreatic secretion - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,96 (96),0.0376,1,, Progesterone-mediated oocyte maturation - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,97 (99),0.038,1,, Glycerophospholipid metabolism - Homo sapiens (human),KEGG,1,PLPL6_HUMAN,97 (97),0.038,1,, Inflammatory mediator regulation of TRP channels - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,99 (99),0.0387,1,, Melanogenesis - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,101 (101),0.0395,1,, Pyrimidine metabolism - Homo sapiens (human),KEGG,1,RPA1_HUMAN,101 (101),0.0395,1,, Parathyroid hormone synthesis_ secretion and action - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,106 (106),0.0414,1,, Purine nucleotides nucleosides metabolism,INOH,1,ADCY6_HUMAN,107 (108),0.0418,1,, Thermogenesis,Wikipathways,1,ADCY6_HUMAN,108 (108),0.0422,1,, NoRC negatively regulates rRNA expression,Reactome,1,RPA1_HUMAN,108 (108),0.0422,1,, Positive epigenetic regulation of rRNA expression,Reactome,1,RPA1_HUMAN,109 (109),0.0426,1,, Negative epigenetic regulation of rRNA expression,Reactome,1,RPA1_HUMAN,111 (111),0.0433,1,, RNA Polymerase I Promoter Clearance,Reactome,1,RPA1_HUMAN,112 (112),0.0437,1,, Cholinergic synapse - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,112 (112),0.0437,1,, RNA Polymerase I Transcription,Reactome,1,RPA1_HUMAN,114 (114),0.0445,1,, Glutamatergic synapse - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,114 (114),0.0445,1,, Vascular smooth muscle contraction - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,121 (121),0.0472,1,, Platelet activation - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,123 (123),0.0479,1,, Oocyte meiosis - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,123 (125),0.0479,1,, Relaxin signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,130 (130),0.0506,1,, Pyrimidine metabolism,EHMN,1,RPA1_HUMAN,136 (136),0.0529,1,, Estrogen signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,137 (137),0.0533,1,, Apelin signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,137 (137),0.0533,1,, Rho GTPase cycle,Reactome,1,SRGP3_HUMAN,140 (144),0.0544,1,, Adrenergic signaling in cardiomyocytes - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,144 (144),0.0559,1,, Phospholipase D signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,145 (146),0.0563,1,, Retrograde endocannabinoid signaling - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,148 (148),0.0574,1,, Calcium Regulation in the Cardiac Cell,Wikipathways,1,ADCY6_HUMAN,149 (149),0.0578,1,, Epigenetic regulation of gene expression,Reactome,1,RPA1_HUMAN,151 (151),0.0586,1,, Oxytocin signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,152 (152),0.059,1,, Neurotransmitter receptors and postsynaptic signal transmission,Reactome,1,ADCY6_HUMAN,153 (153),0.0593,1,, Cushing syndrome - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,154 (154),0.0597,1,, Myometrial Relaxation and Contraction Pathways,Wikipathways,1,ADCY6_HUMAN,155 (155),0.0601,1,, cGMP-PKG signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,163 (163),0.0631,1,, Chemokine signaling pathway,Wikipathways,1,ADCY6_HUMAN,165 (165),0.0639,1,, Axon guidance - Homo sapiens (human),KEGG,1,SRGP3_HUMAN,175 (175),0.0676,1,, Fatty acid metabolism,Reactome,1,ACBD5_HUMAN,187 (189),0.0721,1,, Chemokine signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,189 (189),0.0729,1,, cAMP signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,199 (199),0.0766,1,, Rap1 signaling pathway - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,206 (206),0.0792,1,, Phospholipid metabolism,Reactome,1,PLPL6_HUMAN,215 (216),0.0826,1,, Human T-cell leukemia virus 1 infection - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,219 (219),0.084,1,, Purine metabolism,EHMN,1,RPA1_HUMAN,223 (223),0.0855,1,, Transmission across Chemical Synapses,Reactome,1,ADCY6_HUMAN,224 (224),0.0859,1,, Human cytomegalovirus infection - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,225 (225),0.0863,1,, Thermogenesis - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,229 (229),0.0877,1,, TNFalpha,NetPath,1,RPA1_HUMAN,234 (234),0.0896,1,, Intracellular signaling by second messengers,Reactome,1,ADCY6_HUMAN,245 (245),0.0936,1,, GPCR signaling-G alpha i,INOH,1,ADCY6_HUMAN,262 (262),0.0999,1,, GPCR signaling-pertussis toxin,INOH,1,ADCY6_HUMAN,262 (262),0.0999,1,, GPCR signaling-cholera toxin,INOH,1,ADCY6_HUMAN,270 (270),0.103,1,, GPCR signaling-G alpha s Epac and ERK,INOH,1,ADCY6_HUMAN,272 (272),0.104,1,, GPCR signaling-G alpha s PKA and ERK,INOH,1,ADCY6_HUMAN,285 (285),0.108,1,, Axon guidance,Reactome,1,SRGP3_HUMAN,356 (358),0.134,1,, Neuronal System,Reactome,1,ADCY6_HUMAN,368 (368),0.138,1,, G alpha (i) signalling events,Reactome,1,ADCY6_HUMAN,399 (400),0.149,1,, Signaling by Rho GTPases,Reactome,1,SRGP3_HUMAN,431 (435),0.16,1,, Pathways in cancer - Homo sapiens (human),KEGG,1,ADCY6_HUMAN,525 (526),0.192,1,, G alpha (s) signalling events,Reactome,1,ADCY6_HUMAN,581 (583),0.211,1,, Developmental Biology,Reactome,1,SRGP3_HUMAN,618 (620),0.223,1,, Transport of small molecules,Reactome,1,ADCY6_HUMAN,665 (666),0.238,1,, Signal Transduction,Reactome,2,ADCY6_HUMAN;SRGP3_HUMAN,2634 (2647),0.282,1,, GPCR downstream signalling,Reactome,1,ADCY6_HUMAN,1172 (1176),0.387,1,, Signaling by GPCR,Reactome,1,ADCY6_HUMAN,1235 (1240),0.403,1,, Gene expression (Transcription),Reactome,1,RPA1_HUMAN,1360 (1373),0.436,1,,