pathway_name,pathway_source,num_overlapping_genes,overlapping_genes,num_all_pathway_genes,P_genes,Q_genes,,
Hedgehog,INOH,5,PRS6B_HUMAN;GLI2_HUMAN;PRS4_HUMAN;PSMD2_HUMAN;KIF3A_HUMAN,72 (72),0.000197,0.603,0.00045045,111
FOXM1 transcription factor network,PID,4,CCNA2_HUMAN;XRCC1_HUMAN;NFAC3_HUMAN;CENPF_HUMAN,42 (42),0.000263,0.603,,
TNF alpha Signaling Pathway,Wikipathways,5,CASP7_HUMAN;PYGL_HUMAN;PSMD2_HUMAN;M3K8_HUMAN;THIO_HUMAN,92 (93),0.000615,0.942,,
Human papillomavirus infection - Homo sapiens (human),KEGG,9,TYK2_HUMAN;APC_HUMAN;LAMA5_HUMAN;TENR_HUMAN;PRS4_HUMAN;VATH_HUMAN;FOXO1_HUMAN;CCNA2_HUMAN;INADL_HUMAN,339 (339),0.000955,1,,
One Carbon Metabolism,Wikipathways,3,DNMT1_HUMAN;FOLH1_HUMAN;PUR2_HUMAN,28 (28),0.00115,1,,
DroToll-like,INOH,4,CASP7_HUMAN;PRS6B_HUMAN;PRS4_HUMAN;PSMD2_HUMAN,65 (65),0.0014,1,,
TNFalpha,NetPath,7,PRS4_HUMAN;CASP7_HUMAN;PSMD2_HUMAN;GSLG1_HUMAN;M3K8_HUMAN;FOXO1_HUMAN;THIO_HUMAN,234 (234),0.00182,1,,
E2F transcription factor network,PID,4,CASP7_HUMAN;CCNA2_HUMAN;XRCC1_HUMAN;E2F6_HUMAN,75 (75),0.00237,1,,
Notch,INOH,4,PRS6B_HUMAN;PSMD2_HUMAN;DLL3_HUMAN;PRS4_HUMAN,78 (79),0.00273,1,,
Apoptotic cleavage of cellular proteins,Reactome,3,CASP7_HUMAN;DBNL_HUMAN;APC_HUMAN,38 (38),0.00282,1,,
Sodium/Calcium exchangers,Reactome,2,NCKX4_HUMAN;NCKX2_HUMAN,11 (11),0.00291,1,,
NAD metabolism_ sirtuins and aging,Wikipathways,2,ROS1_HUMAN;FOXO1_HUMAN,11 (11),0.00291,1,,
Peroxisome - Homo sapiens (human),KEGG,4,ABCD2_HUMAN;ECH1_HUMAN;PRDX1_HUMAN;PM34_HUMAN,83 (83),0.00342,1,,
Pyrimidine catabolism,Reactome,2,UPP2_HUMAN;AGT2_HUMAN,12 (12),0.00347,1,,
Caspase-mediated cleavage of cytoskeletal proteins,Reactome,2,CASP7_HUMAN;DBNL_HUMAN,12 (12),0.00347,1,,
Kinesins,Reactome,3,KIF1C_HUMAN;CENPE_HUMAN;KIF3A_HUMAN,43 (43),0.00401,1,,
Proteasome - Homo sapiens (human),KEGG,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,45 (45),0.00456,1,,
JNK signaling in the CD4+ TCR pathway,PID,2,DBNL_HUMAN;M3K8_HUMAN,14 (14),0.00474,1,,
Regulation of sister chromatid separation at the metaphase-anaphase transition,Wikipathways,2,SMC3_HUMAN;CENPE_HUMAN,15 (15),0.00544,1,,
Apoptotic execution phase,Reactome,3,CASP7_HUMAN;DBNL_HUMAN;APC_HUMAN,52 (52),0.00685,1,,
UCH proteinases,Reactome,4,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN;HCFC1_HUMAN,102 (102),0.0071,1,,
internal ribosome entry pathway,BioCarta,2,CASP7_HUMAN;EIF3A_HUMAN,18 (18),0.00781,1,,
Metabolism of nucleotides,Reactome,4,PUR2_HUMAN;UPP2_HUMAN;AGT2_HUMAN;THIO_HUMAN,105 (105),0.00786,1,,
Golgi-to-ER retrograde transport,Reactome,4,KIF1C_HUMAN;CENPE_HUMAN;GALT2_HUMAN;KIF3A_HUMAN,116 (116),0.0111,1,,
TLR JNK,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,62 (62),0.0111,1,,
IL-1 JNK,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,62 (62),0.0111,1,,
Transcription factor regulation in adipogenesis,Wikipathways,2,TWST1_HUMAN;FOXO1_HUMAN,22 (22),0.0116,1,,
TLR p38,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,63 (63),0.0116,1,,
Proteasome Degradation,Wikipathways,3,PRS6B_HUMAN;PRS4_HUMAN;PSMD2_HUMAN,63 (64),0.0116,1,,
Wnt Canonical,INOH,4,PRS6B_HUMAN;APC_HUMAN;PRS4_HUMAN;PSMD2_HUMAN,119 (119),0.0121,1,,
Wnt Mammals,INOH,4,PRS6B_HUMAN;APC_HUMAN;PRS4_HUMAN;PSMD2_HUMAN,119 (119),0.0121,1,,
IL-1 NFkB,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,64 (64),0.0121,1,,
Visual signal transduction: Cones,PID,2,NCKX2_HUMAN;GUC2F_HUMAN,23 (23),0.0126,1,,
Intra-Golgi and retrograde Golgi-to-ER traffic,Reactome,5,KIF1C_HUMAN;GOGA4_HUMAN;CENPE_HUMAN;GALT2_HUMAN;KIF3A_HUMAN,186 (186),0.0127,1,,
IL-1 p38,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,66 (66),0.0132,1,,
TNF,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,67 (67),0.0137,1,,
TLR NFkB,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,69 (69),0.0148,1,,
glycine biosynthesis,HumanCyc,1,AGT2_HUMAN,2 (2),0.0149,1,,
Hydrolysis of LPE,Reactome,1,GPCP1_HUMAN,2 (3),0.0149,1,,
Parkin-Ubiquitin Proteasomal System pathway,Wikipathways,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,72 (73),0.0166,1,,
Epstein-Barr virus infection - Homo sapiens (human),KEGG,5,PRS6B_HUMAN;PSMD2_HUMAN;CCNA2_HUMAN;PRS4_HUMAN;TYK2_HUMAN,200 (201),0.0169,1,,
Gastric Cancer Network 1,Wikipathways,2,APC_HUMAN;CENPF_HUMAN,29 (29),0.0197,1,,
5-aminoimidazole ribonucleotide biosynthesis,HumanCyc,1,PUR2_HUMAN,3 (3),0.0222,1,,
tetrahydrofolate salvage from 5_10-methenyltetrahydrofolate,HumanCyc,1,PUR2_HUMAN,3 (3),0.0222,1,,
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes,Reactome,1,CCNA2_HUMAN,3 (3),0.0222,1,,
pyrimidine ribonucleosides degradation,HumanCyc,1,UPP2_HUMAN,3 (3),0.0222,1,,
Hedgehog _off_ state,Wikipathways,1,GLI2_HUMAN,3 (3),0.0222,1,,
Tumor suppressor activity of SMARCB1,Wikipathways,2,GLI2_HUMAN;DPF1_HUMAN,31 (31),0.0223,1,,
Deubiquitination,Reactome,6,APC_HUMAN;PRS6B_HUMAN;PSMD2_HUMAN;HCFC1_HUMAN;PRS4_HUMAN;CCNA2_HUMAN,296 (296),0.0234,1,,
COPI-dependent Golgi-to-ER retrograde traffic,Reactome,3,KIF1C_HUMAN;CENPE_HUMAN;KIF3A_HUMAN,82 (82),0.0234,1,,
Translocation of GLUT4 to the plasma membrane,Reactome,2,C2CD5_HUMAN;KIF3A_HUMAN,32 (32),0.0237,1,,
Apoptosis - multiple species - Homo sapiens (human),KEGG,2,CASP7_HUMAN;BIRC6_HUMAN,33 (33),0.0251,1,,
Retinoblastoma Gene in Cancer,Wikipathways,3,DNMT1_HUMAN;CCNA2_HUMAN;SMC3_HUMAN,87 (89),0.0273,1,,
Detoxification of Reactive Oxygen Species,Reactome,2,PRDX1_HUMAN;THIO_HUMAN,35 (36),0.028,1,,
Alanine_ aspartate and glutamate metabolism - Homo sapiens (human),KEGG,2,FOLH1_HUMAN;AGT2_HUMAN,35 (35),0.028,1,,
Neutrophil degranulation,Reactome,8,PSMD2_HUMAN;PYGL_HUMAN;CDK13_HUMAN;GRN_HUMAN;OST48_HUMAN;FRPD3_HUMAN;DBNL_HUMAN;MMP8_HUMAN,488 (490),0.0293,1,,
pyrimidine deoxyribonucleosides degradation,HumanCyc,1,UPP2_HUMAN,4 (4),0.0295,1,,
Resolution of AP sites via the single-nucleotide replacement pathway,Reactome,1,XRCC1_HUMAN,4 (4),0.0295,1,,
ALKBH3 mediated reversal of alkylation damage,Reactome,1,ALKB3_HUMAN,4 (4),0.0295,1,,
Regulation of gene expression in beta cells,Reactome,1,FOXO1_HUMAN,4 (4),0.0295,1,,
Regulation of beta-cell development,Reactome,1,FOXO1_HUMAN,4 (4),0.0295,1,,
AKT-mediated inactivation of FOXO1A,Reactome,1,FOXO1_HUMAN,4 (4),0.0295,1,,
Apoptosis Modulation and Signaling,Wikipathways,3,BIRC6_HUMAN;CASP7_HUMAN;PIDD1_HUMAN,90 (91),0.0297,1,,
Nucleobase catabolism,Reactome,2,UPP2_HUMAN;AGT2_HUMAN,37 (37),0.031,1,,
Validated transcriptional targets of AP1 family members Fra1 and Fra2,PID,2,CCNA2_HUMAN;NFAC3_HUMAN,37 (37),0.031,1,,
Purine Nucleoside Phosphorylase Deficiency,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Xanthine Dehydrogenase Deficiency (Xanthinuria),SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Adenylosuccinate Lyase Deficiency,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
AICA-Ribosiduria,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Adenine phosphoribosyltransferase deficiency (APRT),SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Mitochondrial DNA depletion syndrome,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Myoadenylate deaminase deficiency,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Purine Metabolism,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Molybdenum Cofactor Deficiency,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Adenosine Deaminase Deficiency,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Gout or Kelley-Seegmiller Syndrome,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Lesch-Nyhan Syndrome (LNS),SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Xanthinuria type I,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Xanthinuria type II,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,37 (37),0.031,1,,
Th1 and Th2 cell differentiation - Homo sapiens (human),KEGG,3,TYK2_HUMAN;DLL3_HUMAN;NFAC3_HUMAN,92 (92),0.0314,1,,
Hedgehog _on_ state,Reactome,2,GLI2_HUMAN;KIF3A_HUMAN,38 (39),0.0326,1,,
CD4 T cell receptor signaling-NFkB cascade,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,97 (97),0.036,1,,
Interleukin-4 and Interleukin-13 signaling,Wikipathways,3,TWST1_HUMAN;FOXO1_HUMAN;LAMA5_HUMAN,97 (97),0.036,1,,
RUNX2 regulates chondrocyte maturation,Reactome,1,GLI2_HUMAN,5 (5),0.0368,1,,
Activation of caspases through apoptosome-mediated cleavage,Reactome,1,CASP7_HUMAN,5 (5),0.0368,1,,
Cytochrome c-mediated apoptotic response,Reactome,1,CASP7_HUMAN,5 (5),0.0368,1,,
SMAC binds to IAPs ,Reactome,1,CASP7_HUMAN,5 (5),0.0368,1,,
SMAC-mediated dissociation of IAP:caspase complexes ,Reactome,1,CASP7_HUMAN,5 (5),0.0368,1,,
SMAC-mediated apoptotic response,Reactome,1,CASP7_HUMAN,5 (5),0.0368,1,,
G2 Phase,Reactome,1,CCNA2_HUMAN,5 (5),0.0368,1,,
Mitotic G2-G2-M phases,Wikipathways,1,CENPF_HUMAN,5 (5),0.0368,1,,
Hedgehog Signaling Pathway,Wikipathways,2,GLI2_HUMAN;KIF3A_HUMAN,43 (43),0.0409,1,,
Transport of inorganic cations/anions and amino acids/oligopeptides,Reactome,3,NCKX2_HUMAN;S38A3_HUMAN;NCKX4_HUMAN,105 (105),0.0438,1,,
Protein repair,Reactome,1,THIO_HUMAN,6 (6),0.044,1,,
Alpha-oxidation of phytanate,Reactome,1,PM34_HUMAN,6 (6),0.044,1,,
IL-10 signaling,INOH,1,TYK2_HUMAN,6 (6),0.044,1,,
Interleukin-10 signaling,Reactome,1,TYK2_HUMAN,6 (6),0.044,1,,
IL-23 signaling,INOH,1,TYK2_HUMAN,6 (6),0.044,1,,
Refsum Disease,SMPDB,1,ABCD2_HUMAN,6 (6),0.044,1,,
Phytanic Acid Peroxisomal Oxidation,SMPDB,1,ABCD2_HUMAN,6 (6),0.044,1,,
pyrimidine ribonucleosides degradation,HumanCyc,1,UPP2_HUMAN,6 (6),0.044,1,,
Somatroph axis (GH) and its relationship to dietary restriction and aging,Wikipathways,1,FOXO1_HUMAN,6 (6),0.044,1,,
a6b1 and a6b4 Integrin signaling,PID,2,CASP7_HUMAN;LAMA5_HUMAN,45 (45),0.0444,1,,
Cysteine and methionine metabolism - Homo sapiens (human),KEGG,2,DNMT1_HUMAN;AGT2_HUMAN,47 (47),0.048,1,,
IL6-mediated signaling events,PID,2,TYK2_HUMAN;FOXO1_HUMAN,47 (47),0.048,1,,
Hedgehog signaling pathway - Homo sapiens (human),KEGG,2,GLI2_HUMAN;KIF3A_HUMAN,47 (47),0.048,1,,
Mercaptopurine Action Pathway,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,47 (47),0.048,1,,
Thioguanine Action Pathway,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,47 (47),0.048,1,,
Azathioprine Action Pathway,SMPDB,2,PUR2_HUMAN;THIO_HUMAN,47 (47),0.048,1,,
Resolution of Sister Chromatid Cohesion,Reactome,3,SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,109 (109),0.0481,1,,
Hedgehog signaling events mediated by Gli proteins,PID,2,GLI2_HUMAN;KIF3A_HUMAN,48 (48),0.0499,1,,
Mitotic Prometaphase,Reactome,4,ALMS1_HUMAN;SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,186 (186),0.0505,1,,
Calcineurin activates NFAT,Reactome,1,NFAC3_HUMAN,7 (7),0.0511,1,,
Apoptotic factor-mediated response,Reactome,1,CASP7_HUMAN,7 (7),0.0511,1,,
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway,Reactome,1,XRCC1_HUMAN,7 (7),0.0511,1,,
GLI proteins bind promoters of Hh responsive genes to promote transcription,Reactome,1,GLI2_HUMAN,7 (7),0.0511,1,,
Zinc efflux and compartmentalization by the SLC30 family,Reactome,1,ZNT3_HUMAN,7 (7),0.0511,1,,
IL-12 signaling,INOH,1,TYK2_HUMAN,7 (7),0.0511,1,,
Oxidative Stress Regulatory Pathway (Erythrocyte),PharmGKB,1,THIO_HUMAN,7 (7),0.0511,1,,
Reversal of alkylation damage by DNA dioxygenases,Reactome,1,ALKB3_HUMAN,7 (7),0.0511,1,,
Chromatin organization,Reactome,5,KMT2C_HUMAN;RS2_HUMAN;KDM5D_HUMAN;HCFC1_HUMAN;JADE3_HUMAN,271 (272),0.0522,1,,
Chromatin modifying enzymes,Reactome,5,KMT2C_HUMAN;RS2_HUMAN;KDM5D_HUMAN;HCFC1_HUMAN;JADE3_HUMAN,271 (272),0.0522,1,,
Wnt Signaling,Wikipathways,3,CHD8_HUMAN;APC_HUMAN;NFAC3_HUMAN,114 (114),0.0536,1,,
TGF-beta super family signaling pathway canonical,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,115 (115),0.0548,1,,
stat3 signaling pathway,BioCarta,1,TYK2_HUMAN,8 (8),0.0582,1,,
west nile virus,BioCarta,1,CASP7_HUMAN,8 (8),0.0582,1,,
Nef Mediated CD8 Down-regulation,Reactome,1,VATH_HUMAN,8 (8),0.0582,1,,
DNA Damage Reversal,Reactome,1,ALKB3_HUMAN,8 (8),0.0582,1,,
Apoptosis,Reactome,3,CASP7_HUMAN;DBNL_HUMAN;APC_HUMAN,118 (118),0.0583,1,,
Signaling events mediated by PTP1B,PID,2,TYK2_HUMAN;THIO_HUMAN,53 (53),0.0595,1,,
Copper homeostasis,Wikipathways,2,APC_HUMAN;FOXO1_HUMAN,53 (55),0.0595,1,,
Transcriptional Regulation by TP53,Reactome,6,PIDD1_HUMAN;CDK13_HUMAN;RBP56_HUMAN;CCNA2_HUMAN;PRDX1_HUMAN;THIO_HUMAN,372 (374),0.0597,1,,
Programmed Cell Death,Reactome,3,CASP7_HUMAN;DBNL_HUMAN;APC_HUMAN,121 (121),0.0619,1,,
Formation of the ternary complex_ and subsequently_ the 43S complex,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,55 (61),0.0635,1,,
Role of Calcineurin-dependent NFAT signaling in lymphocytes,PID,2,M3K8_HUMAN;NFAC3_HUMAN,55 (56),0.0635,1,,
FSH,NetPath,1,FOXO1_HUMAN,9 (9),0.0653,1,,
AKT phosphorylates targets in the nucleus,Reactome,1,FOXO1_HUMAN,9 (9),0.0653,1,,
no2-dependent il-12 pathway in nk cells,BioCarta,1,TYK2_HUMAN,9 (9),0.0653,1,,
Interleukin-23 signaling,Reactome,1,TYK2_HUMAN,9 (9),0.0653,1,,
MAPK1 (ERK2) activation,Reactome,1,TYK2_HUMAN,9 (9),0.0653,1,,
Nef Mediated CD4 Down-regulation,Reactome,1,VATH_HUMAN,9 (9),0.0653,1,,
glycogenolysis,HumanCyc,1,PYGL_HUMAN,9 (9),0.0653,1,,
ECM proteoglycans,Reactome,2,LAMA5_HUMAN;TENR_HUMAN,56 (57),0.0656,1,,
Caspase Cascade in Apoptosis,PID,2,CASP7_HUMAN;PIDD1_HUMAN,57 (57),0.0676,1,,
Neurexins and neuroligins,Reactome,2,DBNL_HUMAN;HOME3_HUMAN,57 (57),0.0676,1,,
RNA Polymerase II Transcription,Reactome,14,ZNF67_HUMAN;PIDD1_HUMAN;ZNF14_HUMAN;KMT2C_HUMAN;CDK13_HUMAN;GLI2_HUMAN;E2F6_HUMAN;RNPS1_HUMAN;ELL2_HUMAN;RBP56_HUMAN;CCNA2_HUMAN;TWST1_HUMAN;PRDX1_HUMAN;THIO_HUMAN,1223 (1236),0.0696,1,,
Separation of Sister Chromatids,Reactome,3,SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,128 (129),0.0708,1,,
purine nucleotides <i>de novo</i> biosynthesis,HumanCyc,2,PUR2_HUMAN;VATH_HUMAN,59 (59),0.0718,1,,
rRNA processing in the nucleus and cytosol,Reactome,2,RS2_HUMAN;UTP20_HUMAN,59 (59),0.0718,1,,
rRNA modification in the nucleus and cytosol,Reactome,2,RS2_HUMAN;UTP20_HUMAN,59 (59),0.0718,1,,
BCR,NetPath,3,CASP7_HUMAN;FOXO1_HUMAN;NFAC3_HUMAN,129 (129),0.0721,1,,
MTHFR deficiency,Wikipathways,1,DNMT1_HUMAN,10 (10),0.0723,1,,
HDR through MMEJ (alt-NHEJ),Reactome,1,XRCC1_HUMAN,10 (10),0.0723,1,,
The NLRP3 inflammasome,Reactome,1,THIO_HUMAN,10 (10),0.0723,1,,
ifn alpha signaling pathway,BioCarta,1,TYK2_HUMAN,10 (10),0.0723,1,,
Activation of SMO,Reactome,1,KIF3A_HUMAN,10 (10),0.0723,1,,
Cohesin Loading onto Chromatin,Reactome,1,SMC3_HUMAN,10 (10),0.0723,1,,
Hydrolysis of LPC,Reactome,1,GPCP1_HUMAN,10 (11),0.0723,1,,
Interleukin-27 signaling,Reactome,1,TYK2_HUMAN,10 (10),0.0723,1,,
IL-13 signaling,INOH,1,TYK2_HUMAN,10 (10),0.0723,1,,
Beta Oxidation of Very Long Chain Fatty Acids,SMPDB,1,ABCD2_HUMAN,10 (10),0.0723,1,,
Interleukin-12 signaling,Reactome,1,TYK2_HUMAN,10 (10),0.0723,1,,
MAPK3 (ERK1) activation,Reactome,1,TYK2_HUMAN,10 (10),0.0723,1,,
Adrenoleukodystrophy_ X-linked,SMPDB,1,ABCD2_HUMAN,10 (10),0.0723,1,,
Carnitine-acylcarnitine translocase deficiency,SMPDB,1,ABCD2_HUMAN,10 (10),0.0723,1,,
Type III interferon signaling,Wikipathways,1,TYK2_HUMAN,10 (10),0.0723,1,,
Trans-sulfuration pathway,Wikipathways,1,DNMT1_HUMAN,10 (10),0.0723,1,,
CD4 T cell receptor signaling,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,130 (130),0.0734,1,,
Factors involved in megakaryocyte development and platelet production,Reactome,3,KIF1C_HUMAN;CENPE_HUMAN;KIF3A_HUMAN,131 (131),0.0747,1,,
Angiogenesis overview,Wikipathways,2,PLXD1_HUMAN;APC_HUMAN,61 (61),0.0761,1,,
Translation initiation complex formation,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,62 (68),0.0782,1,,
Ribosomal scanning and start codon recognition,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,62 (68),0.0782,1,,
B cell receptor signaling,INOH,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,134 (134),0.0788,1,,
Gene expression (Transcription),Reactome,15,ZNF67_HUMAN;PIDD1_HUMAN;RNPS1_HUMAN;KMT2C_HUMAN;CDK13_HUMAN;GLI2_HUMAN;E2F6_HUMAN;ZNF14_HUMAN;ELL2_HUMAN;RBP56_HUMAN;CCNA2_HUMAN;TWST1_HUMAN;PRDX1_HUMAN;DNMT1_HUMAN;THIO_HUMAN,1360 (1373),0.0791,1,,
CLEC7A (Dectin-1) induces NFAT activation,Reactome,1,NFAC3_HUMAN,11 (11),0.0792,1,,
Alpha6 beta4 integrin-ligand interactions,PID,1,LAMA5_HUMAN,11 (11),0.0792,1,,
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1,Reactome,1,CCNA2_HUMAN,11 (11),0.0792,1,,
apoptotic dna-fragmentation and tissue homeostasis,BioCarta,1,CASP7_HUMAN,11 (11),0.0792,1,,
Pyrimidine salvage,Reactome,1,UPP2_HUMAN,11 (11),0.0792,1,,
Establishment of Sister Chromatid Cohesion,Reactome,1,SMC3_HUMAN,11 (11),0.0792,1,,
il22 soluble receptor signaling pathway,BioCarta,1,TYK2_HUMAN,11 (11),0.0792,1,,
Gamma-glutamyl-transpeptidase deficiency,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
5-oxoprolinase deficiency,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
Gamma-Glutamyltransferase Deficiency,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
Glutathione Metabolism,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
Glutathione Synthetase Deficiency,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
5-Oxoprolinuria,SMPDB,1,CASP7_HUMAN,11 (11),0.0792,1,,
Signaling by NOTCH3,Wikipathways,1,PLXD1_HUMAN,11 (11),0.0792,1,,
Interleukin-6 signaling,Reactome,1,TYK2_HUMAN,11 (11),0.0792,1,,
BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation,Wikipathways,1,FOXO1_HUMAN,11 (11),0.0792,1,,
Activation of the mRNA upon binding of the cap-binding complex and eIFs_ and subsequent binding to 43S,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,63 (69),0.0804,1,,
Basal cell carcinoma - Homo sapiens (human),KEGG,2,GLI2_HUMAN;APC_HUMAN,63 (63),0.0804,1,,
JAK STAT pathway and regulation,INOH,5,PRS6B_HUMAN;TYK2_HUMAN;PRS4_HUMAN;M3K8_HUMAN;PSMD2_HUMAN,310 (310),0.0823,1,,
Ub-specific processing proteases,Reactome,4,PRS6B_HUMAN;PSMD2_HUMAN;CCNA2_HUMAN;PRS4_HUMAN,220 (220),0.0824,1,,
Regulation of retinoblastoma protein,PID,2,CCNA2_HUMAN;DNMT1_HUMAN,64 (64),0.0826,1,,
Integrated Breast Cancer Pathway,Wikipathways,2,GRN_HUMAN;FOXO1_HUMAN,64 (66),0.0826,1,,
G2/M Transition,Reactome,3,ALMS1_HUMAN;CCNA2_HUMAN;CENPF_HUMAN,137 (137),0.0829,1,,
rRNA processing,Reactome,2,RS2_HUMAN;UTP20_HUMAN,65 (65),0.0849,1,,
Oncostatin M Signaling Pathway,Wikipathways,2,CASP7_HUMAN;TYK2_HUMAN,65 (65),0.0849,1,,
Mitotic G2-G2/M phases,Reactome,3,ALMS1_HUMAN;CCNA2_HUMAN;CENPF_HUMAN,139 (139),0.0857,1,,
Mitotic Anaphase,Reactome,3,SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,139 (140),0.0857,1,,
IL9,NetPath,1,TYK2_HUMAN,12 (12),0.0861,1,,
TP53 Regulates Transcription of Caspase Activators and Caspases,Reactome,1,PIDD1_HUMAN,12 (12),0.0861,1,,
Purine ribonucleoside monophosphate biosynthesis,Reactome,1,PUR2_HUMAN,12 (12),0.0861,1,,
Oxidation of Branched Chain Fatty Acids,SMPDB,1,ABCD2_HUMAN,12 (12),0.0861,1,,
TCR signaling in na&#xef;ve CD4+ T cells,PID,2,DBNL_HUMAN;M3K8_HUMAN,66 (68),0.0871,1,,
AGE-RAGE pathway,Wikipathways,2,OST48_HUMAN;FOXO1_HUMAN,66 (66),0.0871,1,,
Mitotic Metaphase and Anaphase,Reactome,3,SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,140 (141),0.0872,1,,
RAC1-PAK1-p38-MMP2 Pathway,Wikipathways,2,CASP7_HUMAN;FOXO1_HUMAN,68 (68),0.0916,1,,
b cell survival pathway,BioCarta,1,CASP7_HUMAN,13 (13),0.0929,1,,
Antimetabolite Pathway - Folate Cycle_ Pharmacodynamics,PharmGKB,1,PUR2_HUMAN,13 (13),0.0929,1,,
Advanced glycosylation endproduct receptor signaling,Reactome,1,OST48_HUMAN,13 (13),0.0929,1,,
Innate Immune System,Reactome,12,NFAC3_HUMAN;PSMD2_HUMAN;PYGL_HUMAN;CDK13_HUMAN;M3K8_HUMAN;GRN_HUMAN;OST48_HUMAN;VATH_HUMAN;FRPD3_HUMAN;DBNL_HUMAN;MMP8_HUMAN;THIO_HUMAN,1067 (1077),0.0993,1,,
Ras signaling in the CD4+ TCR pathway,PID,1,M3K8_HUMAN,14 (14),0.0997,1,,
apoptotic signaling in response to dna damage,BioCarta,1,CASP7_HUMAN,14 (14),0.0997,1,,
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,Reactome,1,CCNA2_HUMAN,14 (14),0.0997,1,,
Mitotic Telophase/Cytokinesis,Reactome,1,SMC3_HUMAN,14 (14),0.0997,1,,
ERK Pathway in Huntington_s Disease,Wikipathways,1,CASP7_HUMAN,14 (14),0.0997,1,,
Wnt signaling pathway - Homo sapiens (human),KEGG,3,CHD8_HUMAN;APC_HUMAN;NFAC3_HUMAN,149 (149),0.1,1,,
Primary Focal Segmental Glomerulosclerosis FSGS,Wikipathways,2,KI67_HUMAN;LAMA5_HUMAN,72 (73),0.101,1,,
MicroRNAs in cancer - Homo sapiens (human),KEGG,3,DNMT1_HUMAN;APC_HUMAN;TENR_HUMAN,150 (299),0.102,1,,
IL6,NetPath,2,TYK2_HUMAN;FOXO1_HUMAN,74 (74),0.106,1,,
Interleukin-4 and 13 signaling,Reactome,1,TYK2_HUMAN,15 (15),0.106,1,,
Interleukin-20 family signaling,Reactome,1,TYK2_HUMAN,15 (15),0.106,1,,
IL-6-type cytokine receptor ligand interactions,Reactome,1,TYK2_HUMAN,15 (15),0.106,1,,
Inflammasomes,Reactome,1,THIO_HUMAN,15 (15),0.106,1,,
Validated nuclear estrogen receptor beta network,PID,1,ZNF14_HUMAN,15 (15),0.106,1,,
il12 and stat4 dependent signaling pathway in th1 development,BioCarta,1,TYK2_HUMAN,15 (15),0.106,1,,
Nucleobase biosynthesis,Reactome,1,PUR2_HUMAN,15 (15),0.106,1,,
Degradation of GLI2 by the proteasome,Reactome,1,GLI2_HUMAN,15 (15),0.106,1,,
Methotrexate Pathway (Cancer Cell)_ Pharmacodynamics,PharmGKB,1,PUR2_HUMAN,15 (15),0.106,1,,
mRNA decay by 5_ to 3_ exoribonuclease,Reactome,1,EDC3_HUMAN,15 (15),0.106,1,,
Transcriptional regulation by RUNX2,Reactome,2,GLI2_HUMAN;TWST1_HUMAN,75 (75),0.108,1,,
Hippo signaling pathway - Homo sapiens (human),KEGG,3,GLI2_HUMAN;APC_HUMAN;INADL_HUMAN,154 (154),0.108,1,,
SLC-mediated transmembrane transport,Reactome,4,NCKX2_HUMAN;S38A3_HUMAN;ZNT3_HUMAN;NCKX4_HUMAN,244 (245),0.11,1,,
Hedgehog Signaling Pathway,Wikipathways,1,GLI2_HUMAN,16 (16),0.113,1,,
Polo-like kinase mediated events,Reactome,1,CENPF_HUMAN,16 (16),0.113,1,,
eukaryotic protein translation,BioCarta,1,EIF3A_HUMAN,16 (17),0.113,1,,
MAP3K8 (TPL2)-dependent MAPK1/3 activation,Reactome,1,M3K8_HUMAN,16 (16),0.113,1,,
Glycogen breakdown (glycogenolysis),Reactome,1,PYGL_HUMAN,16 (16),0.113,1,,
Insulin Signaling,Wikipathways,3,FOXO1_HUMAN;M3K8_HUMAN;KIF3A_HUMAN,160 (160),0.118,1,,
Cellular senescence - Homo sapiens (human),KEGG,3,CCNA2_HUMAN;FOXO1_HUMAN;NFAC3_HUMAN,160 (160),0.118,1,,
RNA degradation - Homo sapiens (human),KEGG,2,PAP1L_HUMAN;EDC3_HUMAN,79 (79),0.118,1,,
Generic Transcription Pathway,Reactome,12,ZNF67_HUMAN;PIDD1_HUMAN;ZNF14_HUMAN;KMT2C_HUMAN;CDK13_HUMAN;GLI2_HUMAN;E2F6_HUMAN;RBP56_HUMAN;CCNA2_HUMAN;TWST1_HUMAN;PRDX1_HUMAN;THIO_HUMAN,1101 (1107),0.118,1,,
Zinc transporters,Reactome,1,ZNT3_HUMAN,17 (17),0.12,1,,
prion pathway,BioCarta,1,LAMA5_HUMAN,17 (19),0.12,1,,
Beta-catenin phosphorylation cascade,Reactome,1,APC_HUMAN,17 (17),0.12,1,,
NOTCH1 regulation of human endothelial cell calcification,Wikipathways,1,DLL3_HUMAN,17 (17),0.12,1,,
Regulation of Wnt-B-catenin Signaling by Small Molecule Compounds,Wikipathways,1,APC_HUMAN,17 (17),0.12,1,,
miR-509-3p alteration of YAP1-ECM axis,Wikipathways,1,TWST1_HUMAN,17 (18),0.12,1,,
Regulation of nuclear beta catenin signaling and target gene transcription,PID,2,CHD8_HUMAN;APC_HUMAN,80 (80),0.12,1,,
Signaling by Hedgehog,Reactome,2,GLI2_HUMAN;KIF3A_HUMAN,81 (82),0.123,1,,
ECM-receptor interaction - Homo sapiens (human),KEGG,2,TENR_HUMAN;LAMA5_HUMAN,82 (82),0.125,1,,
Selenium Micronutrient Network,Wikipathways,2,PRDX1_HUMAN;THIO_HUMAN,82 (83),0.125,1,,
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer_s disease models,Reactome,1,PRDX1_HUMAN,18 (18),0.126,1,,
Neurodegenerative Diseases,Reactome,1,PRDX1_HUMAN,18 (18),0.126,1,,
ABC transporters in lipid homeostasis,Reactome,1,ABCD2_HUMAN,18 (18),0.126,1,,
Degradation of beta catenin,PID,1,APC_HUMAN,18 (18),0.126,1,,
SCF(Skp2)-mediated degradation of p27/p21,Reactome,1,CCNA2_HUMAN,18 (18),0.126,1,,
regulation of cell cycle progression by plk3,BioCarta,1,CASP7_HUMAN,18 (18),0.126,1,,
Protein methylation,Reactome,1,RS2_HUMAN,18 (18),0.126,1,,
Glycogen synthetase deficiency,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Glycogenosis_ Type III. Cori disease_ Debrancher glycogenosis,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Mucopolysaccharidosis VI. Sly syndrome,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Sucrase-isomaltase deficiency,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Glycogenosis_ Type IV. Amylopectinosis_ Anderson disease,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Glycogenosis_ Type VI. Hers disease,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
Starch and Sucrose Metabolism,SMPDB,1,PYGL_HUMAN,18 (18),0.126,1,,
MET activates PTK2 signaling,Reactome,1,LAMA5_HUMAN,18 (18),0.126,1,,
RNA transport - Homo sapiens (human),KEGG,3,PAP1L_HUMAN;RNPS1_HUMAN;EIF3A_HUMAN,166 (171),0.127,1,,
ncRNAs involved in Wnt signaling in hepatocellular carcinoma,Wikipathways,2,CHD8_HUMAN;APC_HUMAN,84 (86),0.13,1,,
Global Genome Nucleotide Excision Repair (GG-NER),Reactome,2,XRCC1_HUMAN;CHD1L_HUMAN,84 (84),0.13,1,,
Interleukin-12 family signaling,Reactome,1,TYK2_HUMAN,19 (19),0.133,1,,
akt signaling pathway,BioCarta,1,FOXO1_HUMAN,19 (19),0.133,1,,
Other semaphorin interactions,Reactome,1,PLXD1_HUMAN,19 (19),0.133,1,,
ATM Signaling Pathway,Wikipathways,1,PIDD1_HUMAN,19 (19),0.133,1,,
Hematopoietic Stem Cell Gene Regulation by GABP alpha-beta Complex,Wikipathways,1,DNMT1_HUMAN,19 (19),0.133,1,,
Apoptosis Modulation by HSP70,Wikipathways,1,CASP7_HUMAN,19 (19),0.133,1,,
Mitochondrial Gene Expression,Wikipathways,1,HCFC1_HUMAN,19 (19),0.133,1,,
TP53 Regulates Metabolic Genes,Reactome,2,PRDX1_HUMAN;THIO_HUMAN,86 (86),0.135,1,,
One carbon pool by folate - Homo sapiens (human),KEGG,1,PUR2_HUMAN,20 (20),0.139,1,,
Canonical Wnt signaling pathway,PID,1,APC_HUMAN,20 (20),0.139,1,,
fas signaling pathway (cd95),BioCarta,1,CASP7_HUMAN,20 (20),0.139,1,,
NOTCH3 Intracellular Domain Regulates Transcription,Reactome,1,PLXD1_HUMAN,20 (20),0.139,1,,
S-Adenosylhomocysteine (SAH) Hydrolase Deficiency,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Methionine Metabolism,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Methionine Adenosyltransferase Deficiency,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Glycine N-methyltransferase Deficiency,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Hypermethioninemia,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Methylenetetrahydrofolate Reductase Deficiency (MTHFRD),SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism_ cblG complementation type,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Cystathionine Beta-Synthase Deficiency,SMPDB,1,DNMT1_HUMAN,20 (20),0.139,1,,
Globo Sphingolipid Metabolism,Wikipathways,1,GALT2_HUMAN,20 (20),0.139,1,,
Mitotic G1-G1-S phases,Wikipathways,1,CCNA2_HUMAN,20 (20),0.139,1,,
Nanomaterial induced apoptosis,Wikipathways,1,CASP7_HUMAN,20 (20),0.139,1,,
Protein-protein interactions at synapses,Reactome,2,DBNL_HUMAN;HOME3_HUMAN,88 (88),0.14,1,,
Androgen receptor signaling pathway,Wikipathways,2,PRDX1_HUMAN;FOXO1_HUMAN,89 (89),0.143,1,,
T-Cell antigen Receptor (TCR) Signaling Pathway,Wikipathways,2,DBNL_HUMAN;M3K8_HUMAN,90 (92),0.145,1,,
p53-Dependent G1 DNA Damage Response,Reactome,1,CCNA2_HUMAN,21 (21),0.146,1,,
p53-Dependent G1/S DNA damage checkpoint,Reactome,1,CCNA2_HUMAN,21 (21),0.146,1,,
IFN alpha signaling,INOH,1,TYK2_HUMAN,21 (21),0.146,1,,
Valproic Acid Pathway_ Pharmacokinetics,PharmGKB,1,ECH1_HUMAN,21 (21),0.146,1,,
mRNA surveillance pathway - Homo sapiens (human),KEGG,2,PAP1L_HUMAN;RNPS1_HUMAN,91 (91),0.148,1,,
mRNA Splicing - Major Pathway,Reactome,3,RNPS1_HUMAN;CWC25_HUMAN;ROA2_HUMAN,178 (178),0.148,1,,
Human Complement System,Wikipathways,2,LAMA5_HUMAN;THIO_HUMAN,92 (92),0.151,1,,
CD28 dependent PI3K/Akt signaling,Reactome,1,M3K8_HUMAN,22 (22),0.152,1,,
IGF-Core,Signalink,1,FOXO1_HUMAN,22 (22),0.152,1,,
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters,Reactome,1,VATH_HUMAN,22 (22),0.152,1,,
Interleukin-6 family signaling,Reactome,1,TYK2_HUMAN,22 (22),0.152,1,,
Fatty Acid Biosynthesis,Wikipathways,1,ECH1_HUMAN,22 (22),0.152,1,,
Wnt-beta-catenin Signaling Pathway in Leukemia,Wikipathways,1,APC_HUMAN,22 (22),0.152,1,,
Glycogen metabolism,Reactome,1,PYGL_HUMAN,22 (22),0.152,1,,
The human immune response to tuberculosis,Wikipathways,1,TYK2_HUMAN,22 (22),0.152,1,,
LncRNA involvement in canonical Wnt signaling and colorectal cancer,Wikipathways,2,CHD8_HUMAN;APC_HUMAN,93 (97),0.153,1,,
Regulation of TP53 Activity through Phosphorylation,Reactome,2,CCNA2_HUMAN;RBP56_HUMAN,93 (93),0.153,1,,
induction of apoptosis through dr3 and dr4/5 death receptors,BioCarta,1,CASP7_HUMAN,23 (23),0.159,1,,
Laminin interactions,Reactome,1,LAMA5_HUMAN,23 (23),0.159,1,,
Signaling events mediated by the Hedgehog family,PID,1,GLI2_HUMAN,23 (23),0.159,1,,
Signaling events mediated by PRL,PID,1,CCNA2_HUMAN,23 (23),0.159,1,,
tumor suppressor arf inhibits ribosomal biogenesis,BioCarta,1,TWST1_HUMAN,23 (24),0.159,1,,
Proximal tubule bicarbonate reclamation - Homo sapiens (human),KEGG,1,S38A3_HUMAN,23 (23),0.159,1,,
Nucleotide salvage,Reactome,1,UPP2_HUMAN,23 (23),0.159,1,,
caspase cascade in apoptosis,BioCarta,1,CASP7_HUMAN,23 (23),0.159,1,,
RAF-independent MAPK1/3 activation,Reactome,1,TYK2_HUMAN,23 (23),0.159,1,,
G1/S DNA Damage Checkpoints,Reactome,1,CCNA2_HUMAN,23 (23),0.159,1,,
Pyrimidine Metabolism,SMPDB,1,UPP2_HUMAN,23 (23),0.159,1,,
UMP Synthase Deiciency (Orotic Aciduria),SMPDB,1,UPP2_HUMAN,23 (23),0.159,1,,
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy),SMPDB,1,UPP2_HUMAN,23 (23),0.159,1,,
Beta Ureidopropionase Deficiency,SMPDB,1,UPP2_HUMAN,23 (23),0.159,1,,
Dihydropyrimidinase Deficiency,SMPDB,1,UPP2_HUMAN,23 (23),0.159,1,,
Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal,Reactome,2,CENPE_HUMAN;CENPF_HUMAN,96 (96),0.161,1,,
Amplification of signal from the kinetochores,Reactome,2,CENPE_HUMAN;CENPF_HUMAN,96 (96),0.161,1,,
mRNA Splicing,Reactome,3,RNPS1_HUMAN;CWC25_HUMAN;ROA2_HUMAN,186 (186),0.162,1,,
Visual signal transduction: Rods,PID,1,GUC2F_HUMAN,24 (24),0.165,1,,
Plexin-D1 Signaling,PID,1,PLXD1_HUMAN,24 (24),0.165,1,,
Vitamin digestion and absorption - Homo sapiens (human),KEGG,1,FOLH1_HUMAN,24 (24),0.165,1,,
Fluoropyrimidine Pathway_ Pharmacokinetics,PharmGKB,1,UPP2_HUMAN,24 (24),0.165,1,,
Transcriptional activation of mitochondrial biogenesis,Reactome,1,HCFC1_HUMAN,24 (27),0.165,1,,
Miscellaneous transport and binding events,Reactome,1,ADDB_HUMAN,24 (24),0.165,1,,
B Cell Receptor Signaling Pathway,Wikipathways,2,FOXO1_HUMAN;NFAC3_HUMAN,98 (98),0.166,1,,
G0 and Early G1,Reactome,1,CCNA2_HUMAN,25 (25),0.171,1,,
Alanine Aspartate Asparagine metabolism,INOH,1,AGT2_HUMAN,25 (25),0.171,1,,
mtor signaling pathway,BioCarta,1,EIF3A_HUMAN,25 (25),0.171,1,,
regulation of eif-4e and p70s6 kinase,BioCarta,1,PRS6B_HUMAN,25 (25),0.171,1,,
skeletal muscle hypertrophy is regulated via akt-mtor pathway,BioCarta,1,PRS6B_HUMAN,25 (25),0.171,1,,
Hedgehog,NetPath,1,GLI2_HUMAN,25 (25),0.171,1,,
Cyclin A/B1/B2 associated events during G2/M transition,Reactome,1,CCNA2_HUMAN,25 (25),0.171,1,,
Constitutive Signaling by AKT1 E17K in Cancer,Reactome,1,FOXO1_HUMAN,25 (25),0.171,1,,
Gap-filling DNA repair synthesis and ligation in GG-NER,Reactome,1,XRCC1_HUMAN,25 (25),0.171,1,,
T cell receptor signaling pathway - Homo sapiens (human),KEGG,2,M3K8_HUMAN;NFAC3_HUMAN,101 (101),0.174,1,,
Neural Crest Differentiation,Wikipathways,2,DLL3_HUMAN;TWST1_HUMAN,101 (101),0.174,1,,
Extracellular matrix organization,Reactome,4,TENR_HUMAN;MMP8_HUMAN;ATS14_HUMAN;LAMA5_HUMAN,293 (294),0.176,1,,
S Phase,Reactome,2,CCNA2_HUMAN;SMC3_HUMAN,102 (103),0.177,1,,
Insulin receptor recycling,Reactome,1,VATH_HUMAN,26 (26),0.177,1,,
IL27-mediated signaling events,PID,1,TYK2_HUMAN,26 (26),0.177,1,,
Other interleukin signaling,Reactome,1,TYK2_HUMAN,26 (26),0.177,1,,
Metal ion SLC transporters,Reactome,1,ZNT3_HUMAN,26 (26),0.177,1,,
Orc1 removal from chromatin,Reactome,1,CCNA2_HUMAN,26 (26),0.177,1,,
Regulation of IFNA signaling,Reactome,1,TYK2_HUMAN,26 (26),0.177,1,,
Glucagon signaling pathway - Homo sapiens (human),KEGG,2,FOXO1_HUMAN;PYGL_HUMAN,103 (103),0.18,1,,
Liver steatosis AOP,Wikipathways,2,ECH1_HUMAN;FOXO1_HUMAN,103 (103),0.18,1,,
IL-7,NetPath,1,FOXO1_HUMAN,27 (27),0.183,1,,
thrombin signaling and protease-activated receptors,BioCarta,1,BIG2_HUMAN,27 (27),0.183,1,,
CDK-mediated phosphorylation and removal of Cdc6,Reactome,1,CCNA2_HUMAN,27 (28),0.183,1,,
Cdc20:Phospho-APC/C mediated degradation of Cyclin A,Reactome,1,CCNA2_HUMAN,27 (28),0.183,1,,
MET promotes cell motility,Reactome,1,LAMA5_HUMAN,27 (27),0.183,1,,
Follicle Stimulating Hormone (FSH) signaling pathway,Wikipathways,1,FOXO1_HUMAN,27 (27),0.183,1,,
Canonical and Non-canonical Notch signaling,Wikipathways,1,DLL3_HUMAN,27 (27),0.183,1,,
Degradation of the extracellular matrix,Reactome,2,MMP8_HUMAN;LAMA5_HUMAN,105 (105),0.185,1,,
Formation of a pool of free 40S subunits,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,105 (115),0.185,1,,
JAK-STAT,Wikipathways,2,TWST1_HUMAN;FOXO1_HUMAN,106 (106),0.188,1,,
DNA Damage/Telomere Stress Induced Senescence,Reactome,1,CCNA2_HUMAN,28 (28),0.19,1,,
adp-ribosylation factor,BioCarta,1,BIG2_HUMAN,28 (28),0.19,1,,
Phototransduction - Homo sapiens (human),KEGG,1,GUC2F_HUMAN,28 (28),0.19,1,,
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint,Reactome,1,CCNA2_HUMAN,28 (29),0.19,1,,
NOTCH-Ncore,Signalink,1,DLL3_HUMAN,28 (28),0.19,1,,
Omega-6 fatty acid metabolism,EHMN,1,ECH1_HUMAN,28 (28),0.19,1,,
Regulation of RUNX2 expression and activity,Reactome,1,TWST1_HUMAN,28 (28),0.19,1,,
Insulin resistance - Homo sapiens (human),KEGG,2,FOXO1_HUMAN;PYGL_HUMAN,107 (107),0.19,1,,
Th17 cell differentiation - Homo sapiens (human),KEGG,2,TYK2_HUMAN;NFAC3_HUMAN,107 (107),0.19,1,,
Purine nucleotides nucleosides metabolism,INOH,2,PUR2_HUMAN;GUC2F_HUMAN,107 (108),0.19,1,,
p38 MAPK signaling pathway,PID,1,THIO_HUMAN,29 (29),0.196,1,,
Calcium signaling in the CD4+ TCR pathway,PID,1,NFAC3_HUMAN,29 (29),0.196,1,,
Peroxisomal lipid metabolism,Reactome,1,PM34_HUMAN,29 (29),0.196,1,,
Cyclin E associated events during G1/S transition ,Reactome,1,CCNA2_HUMAN,29 (29),0.196,1,,
Cyclin A:Cdk2-associated events at S phase entry,Reactome,1,CCNA2_HUMAN,29 (29),0.196,1,,
Disassembly of the destruction complex and recruitment of AXIN to the membrane,Reactome,1,APC_HUMAN,29 (29),0.196,1,,
The role of Nef in HIV-1 replication and disease pathogenesis,Reactome,1,VATH_HUMAN,29 (29),0.196,1,,
TP53 Regulates Transcription of Cell Death Genes,Wikipathways,1,PIDD1_HUMAN,29 (29),0.196,1,,
Nonsense-Mediated Decay (NMD),Reactome,2,RNPS1_HUMAN;RS2_HUMAN,109 (118),0.196,1,,
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC),Reactome,2,RNPS1_HUMAN;RS2_HUMAN,109 (118),0.196,1,,
TNF signaling pathway - Homo sapiens (human),KEGG,2,CASP7_HUMAN;M3K8_HUMAN,110 (110),0.198,1,,
Pathways in cancer - Homo sapiens (human),KEGG,6,APC_HUMAN;LAMA5_HUMAN;CASP7_HUMAN;GLI2_HUMAN;FOXO1_HUMAN;DLL3_HUMAN,525 (526),0.198,1,,
IL2 signaling events mediated by STAT5,PID,1,CCNA2_HUMAN,30 (30),0.202,1,,
Downstream signaling events of B Cell Receptor (BCR),Reactome,1,NFAC3_HUMAN,30 (30),0.202,1,,
Regulation of CDC42 activity,PID,1,APC_HUMAN,30 (30),0.202,1,,
Deactivation of the beta-catenin transactivating complex,Reactome,1,CHD8_HUMAN,30 (30),0.202,1,,
Dopaminergic Neurogenesis,Wikipathways,1,GLI2_HUMAN,30 (30),0.202,1,,
mucin core 1 and core 2 <i>O</i>-glycosylation,HumanCyc,1,GALT2_HUMAN,30 (30),0.202,1,,
APC/C:Cdc20 mediated degradation of mitotic proteins,Reactome,1,CCNA2_HUMAN,30 (31),0.202,1,,
Tight junction interactions,Reactome,1,INADL_HUMAN,30 (31),0.202,1,,
Extracellular vesicle-mediated signaling in recipient cells,Wikipathways,1,APC_HUMAN,30 (30),0.202,1,,
PI3K-AKT-mTOR signaling pathway and therapeutic opportunities,Wikipathways,1,FOXO1_HUMAN,30 (30),0.202,1,,
Mitotic Spindle Checkpoint,Reactome,2,CENPE_HUMAN;CENPF_HUMAN,112 (113),0.204,1,,
Nucleotide Excision Repair,Reactome,2,XRCC1_HUMAN;CHD1L_HUMAN,112 (113),0.204,1,,
Toxoplasmosis - Homo sapiens (human),KEGG,2,TYK2_HUMAN;LAMA5_HUMAN,113 (113),0.207,1,,
Transferrin endocytosis and recycling,Reactome,1,VATH_HUMAN,31 (31),0.208,1,,
Mucin type O-glycan biosynthesis - Homo sapiens (human),KEGG,1,GALT2_HUMAN,31 (31),0.208,1,,
Folate metabolism,INOH,1,PUR2_HUMAN,31 (31),0.208,1,,
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,Reactome,1,CCNA2_HUMAN,31 (32),0.208,1,,
Matrix Metalloproteinases,Wikipathways,1,MMP8_HUMAN,31 (31),0.208,1,,
Gastric Cancer Network 2,Wikipathways,1,CTF8A_HUMAN,31 (32),0.208,1,,
Trans-sulfuration and one carbon metabolism,Wikipathways,1,DNMT1_HUMAN,31 (31),0.208,1,,
miRNA regulation of prostate cancer signaling pathways,Wikipathways,1,FOXO1_HUMAN,31 (45),0.208,1,,
Nuclear Receptors Meta-Pathway,Wikipathways,4,PRDX1_HUMAN;NAV3_HUMAN;FOXO1_HUMAN;THIO_HUMAN,315 (316),0.209,1,,
SRP-dependent cotranslational protein targeting to membrane,Reactome,2,OST48_HUMAN;RS2_HUMAN,114 (124),0.209,1,,
Glutamatergic synapse - Homo sapiens (human),KEGG,2,HOME3_HUMAN;S38A3_HUMAN,114 (114),0.209,1,,
L13a-mediated translational silencing of Ceruloplasmin expression,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,115 (125),0.212,1,,
Ciliary landscape,Wikipathways,3,PRS6B_HUMAN;ZY11B_HUMAN;APC_HUMAN,213 (213),0.213,1,,
RUNX2 regulates bone development,Reactome,1,GLI2_HUMAN,32 (32),0.214,1,,
ROS_ RNS production in phagocytes,Reactome,1,VATH_HUMAN,32 (32),0.214,1,,
Amino acid transport across the plasma membrane,Reactome,1,S38A3_HUMAN,32 (32),0.214,1,,
Glyoxylate metabolism and glycine degradation,Reactome,1,AGT2_HUMAN,32 (32),0.214,1,,
Thiopurine Pathway_ Pharmacokinetics/Pharmacodynamics,PharmGKB,1,PUR2_HUMAN,32 (32),0.214,1,,
Constitutive Androstane Receptor Pathway,Wikipathways,1,FOXO1_HUMAN,32 (32),0.214,1,,
Initiation of transcription and translation elongation at the HIV-1 LTR,Wikipathways,1,NFAC3_HUMAN,32 (32),0.214,1,,
White fat cell differentiation,Wikipathways,1,FOXO1_HUMAN,32 (32),0.214,1,,
DNA Repair,Reactome,4,ALKB3_HUMAN;CCNA2_HUMAN;XRCC1_HUMAN;CHD1L_HUMAN,318 (320),0.214,1,,
GTP hydrolysis and joining of the 60S ribosomal subunit,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,116 (126),0.215,1,,
O-linked glycosylation,Reactome,2,ATS14_HUMAN;GALT2_HUMAN,116 (116),0.215,1,,
Inflammatory Response Pathway,Wikipathways,1,LAMA5_HUMAN,33 (33),0.219,1,,
CD28 co-stimulation,Reactome,1,M3K8_HUMAN,33 (33),0.219,1,,
Base excision repair - Homo sapiens (human),KEGG,1,XRCC1_HUMAN,33 (33),0.219,1,,
Nuclear Receptors in Lipid Metabolism and Toxicity,Wikipathways,1,ABCD2_HUMAN,33 (35),0.219,1,,
Fluoropyrimidine Activity,Wikipathways,1,UPP2_HUMAN,33 (34),0.219,1,,
Alpha 6 Beta 4 signaling pathway,Wikipathways,1,LAMA5_HUMAN,33 (33),0.219,1,,
Pregnane X Receptor pathway,Wikipathways,1,FOXO1_HUMAN,33 (33),0.219,1,,
Prion disease pathway,Wikipathways,1,SMC3_HUMAN,33 (33),0.219,1,,
Interconversion of nucleotide di- and triphosphates,Reactome,1,THIO_HUMAN,34 (34),0.225,1,,
ATM pathway,PID,1,SMC3_HUMAN,34 (34),0.225,1,,
SNARE interactions in vesicular transport - Homo sapiens (human),KEGG,1,VTI1B_HUMAN,34 (34),0.225,1,,
Amino acid synthesis and interconversion (transamination),Reactome,1,FOLH1_HUMAN,34 (35),0.225,1,,
COPI-independent Golgi-to-ER retrograde traffic,Reactome,1,GALT2_HUMAN,34 (34),0.225,1,,
Inactivation_ recovery and regulation of the phototransduction cascade,Reactome,1,GUC2F_HUMAN,34 (34),0.225,1,,
N-glycan trimming in the ER and Calnexin/Calreticulin cycle,Reactome,1,PRS4_HUMAN,34 (34),0.225,1,,
Melatonin metabolism and effects,Wikipathways,1,FOXO1_HUMAN,34 (34),0.225,1,,
AMPK signaling pathway - Homo sapiens (human),KEGG,2,CCNA2_HUMAN;FOXO1_HUMAN,120 (120),0.226,1,,
Cell Cycle,Wikipathways,2,CCNA2_HUMAN;SMC3_HUMAN,120 (120),0.226,1,,
Transport of small molecules,Reactome,7,NCKX4_HUMAN;ZNT3_HUMAN;ABCD2_HUMAN;NCKX2_HUMAN;S38A3_HUMAN;VATH_HUMAN;ADDB_HUMAN,665 (666),0.228,1,,
Transcriptional Regulation by E2F6,Reactome,1,E2F6_HUMAN,35 (35),0.231,1,,
Collagen degradation,Reactome,1,MMP8_HUMAN,35 (35),0.231,1,,
HIV-1 Nef: Negative effector of Fas and TNF-alpha,PID,1,CASP7_HUMAN,35 (35),0.231,1,,
Striated Muscle Contraction,Reactome,1,MYH7_HUMAN,35 (35),0.231,1,,
HIF-2-alpha transcription factor network,PID,1,TWST1_HUMAN,35 (35),0.231,1,,
Class I PI3K signaling events mediated by Akt,PID,1,FOXO1_HUMAN,35 (35),0.231,1,,
The phototransduction cascade,Reactome,1,GUC2F_HUMAN,35 (35),0.231,1,,
Regulation of APC/C activators between G1/S and early anaphase,Reactome,1,CCNA2_HUMAN,35 (36),0.231,1,,
Histidine metabolism,EHMN,1,S38A3_HUMAN,35 (35),0.231,1,,
RHO GTPases Activate Formins,Reactome,2,CENPE_HUMAN;CENPF_HUMAN,123 (123),0.234,1,,
Cap-dependent Translation Initiation,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,123 (133),0.234,1,,
Eukaryotic Translation Initiation,Reactome,2,RS2_HUMAN;EIF3A_HUMAN,123 (133),0.234,1,,
Glycogen Synthesis and Degradation,Wikipathways,1,PYGL_HUMAN,36 (36),0.237,1,,
Starch and sucrose metabolism - Homo sapiens (human),KEGG,1,PYGL_HUMAN,36 (36),0.237,1,,
Regulation of TP53 Degradation,Reactome,1,CCNA2_HUMAN,36 (36),0.237,1,,
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation,Wikipathways,1,ROA2_HUMAN,36 (36),0.237,1,,
Cell cycle - Homo sapiens (human),KEGG,2,CCNA2_HUMAN;SMC3_HUMAN,124 (124),0.237,1,,
mRNA Processing,Wikipathways,2,RNPS1_HUMAN;ROA2_HUMAN,125 (127),0.24,1,,
miR-targeted genes in leukocytes - TarBase,Wikipathways,2,PLXD1_HUMAN;M3K8_HUMAN,126 (154),0.242,1,,
MAPK6/MAPK4 signaling,Reactome,1,FOXO1_HUMAN,37 (39),0.243,1,,
IL23-mediated signaling events,PID,1,TYK2_HUMAN,37 (37),0.243,1,,
IL2 signaling events mediated by PI3K,PID,1,EIF3A_HUMAN,37 (37),0.243,1,,
ATR signaling pathway,PID,1,CCNA2_HUMAN,37 (37),0.243,1,,
trefoil factors initiate mucosal healing,BioCarta,1,CASP7_HUMAN,37 (37),0.243,1,,
Resolution of Abasic Sites (AP sites),Reactome,1,XRCC1_HUMAN,37 (37),0.243,1,,
Base Excision Repair,Reactome,1,XRCC1_HUMAN,37 (37),0.243,1,,
Regulation of TP53 Expression and Degradation,Reactome,1,CCNA2_HUMAN,37 (37),0.243,1,,
O-Glycan biosynthesis,EHMN,1,GALT2_HUMAN,37 (37),0.243,1,,
Zinc homeostasis,Wikipathways,1,ZNT3_HUMAN,37 (37),0.243,1,,
M Phase,Reactome,4,ALMS1_HUMAN;SMC3_HUMAN;CENPE_HUMAN;CENPF_HUMAN,338 (340),0.246,1,,
adenosine ribonucleotides <i>de novo</i> biosynthesis,HumanCyc,1,VATH_HUMAN,38 (38),0.248,1,,
Ovarian tumor domain proteases,Reactome,1,APC_HUMAN,38 (38),0.248,1,,
Parkinsons Disease Pathway,Wikipathways,1,CASP7_HUMAN,38 (71),0.248,1,,
Adipogenesis,Wikipathways,2,TWST1_HUMAN;FOXO1_HUMAN,130 (131),0.253,1,,
Degradation of beta-catenin by the destruction complex,Reactome,1,APC_HUMAN,39 (39),0.254,1,,
Signaling events mediated by HDAC Class III,PID,1,FOXO1_HUMAN,39 (39),0.254,1,,
Association of TriC/CCT with target proteins during biosynthesis,Reactome,1,BIG2_HUMAN,39 (39),0.254,1,,
O-glycosylation of TSR domain-containing proteins,Reactome,1,ATS14_HUMAN,39 (39),0.254,1,,
Neddylation,Reactome,3,PRS6B_HUMAN;PSMD2_HUMAN;PRS4_HUMAN,234 (235),0.255,1,,
Angiopoietin Like Protein 8 Regulatory Pathway,Wikipathways,2,FOXO1_HUMAN;M3K8_HUMAN,131 (131),0.256,1,,
FoxO signaling pathway - Homo sapiens (human),KEGG,2,FOXO1_HUMAN;HOME3_HUMAN,132 (132),0.259,1,,
CLEC7A (Dectin-1) signaling,Reactome,1,NFAC3_HUMAN,40 (40),0.259,1,,
Glycine_ serine and threonine metabolism - Homo sapiens (human),KEGG,1,AGT2_HUMAN,40 (40),0.259,1,,
APC/C-mediated degradation of cell cycle proteins,Reactome,1,CCNA2_HUMAN,40 (41),0.259,1,,
Regulation of mitotic cell cycle,Reactome,1,CCNA2_HUMAN,40 (41),0.259,1,,
Organelle biogenesis and maintenance,Reactome,3,ALMS1_HUMAN;HCFC1_HUMAN;KIF3A_HUMAN,237 (240),0.261,1,,
Metabolism of RNA,Reactome,6,CWC25_HUMAN;RNPS1_HUMAN;RS2_HUMAN;UTP20_HUMAN;ROA2_HUMAN;EDC3_HUMAN,577 (586),0.262,1,,
Glycine Serine metabolism,INOH,1,AGT2_HUMAN,41 (41),0.265,1,,
Dual Incision in GG-NER,Reactome,1,CHD1L_HUMAN,41 (41),0.265,1,,
Nucleotide-binding Oligomerization Domain (NOD) pathway,Wikipathways,1,CASP7_HUMAN,41 (41),0.265,1,,
TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway,Wikipathways,1,CASP7_HUMAN,41 (41),0.265,1,,
Intraflagellar transport,Reactome,1,KIF3A_HUMAN,41 (41),0.265,1,,
Processing of Capped Intron-Containing Pre-mRNA,Reactome,3,RNPS1_HUMAN;CWC25_HUMAN;ROA2_HUMAN,240 (240),0.267,1,,
Membrane Trafficking,Reactome,6,CENPE_HUMAN;C2CD5_HUMAN;GOGA4_HUMAN;KIF3A_HUMAN;KIF1C_HUMAN;GALT2_HUMAN,582 (582),0.268,1,,
Apoptosis - Homo sapiens (human),KEGG,2,CASP7_HUMAN;PIDD1_HUMAN,136 (136),0.27,1,,
Metabolic reprogramming in colon cancer,Wikipathways,1,PUR2_HUMAN,42 (42),0.271,1,,
actions of nitric oxide in the heart,BioCarta,1,GUC2F_HUMAN,42 (42),0.271,1,,
Non-integrin membrane-ECM interactions,Reactome,1,LAMA5_HUMAN,42 (42),0.271,1,,
N-Glycan biosynthesis,EHMN,1,OST48_HUMAN,42 (42),0.271,1,,
Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation,Wikipathways,1,CASP7_HUMAN,42 (43),0.271,1,,
Insulin signaling pathway - Homo sapiens (human),KEGG,2,FOXO1_HUMAN;PYGL_HUMAN,137 (137),0.273,1,,
Endocytosis - Homo sapiens (human),KEGG,3,KIF5C_HUMAN;SNX1_HUMAN;BIG2_HUMAN,244 (244),0.275,1,,
PAR1-mediated thrombin signaling events,PID,1,SNX1_HUMAN,43 (44),0.276,1,,
Syndecan-1-mediated signaling events,PID,1,LAMA5_HUMAN,43 (43),0.276,1,,
Intrinsic Pathway for Apoptosis,Reactome,1,CASP7_HUMAN,43 (43),0.276,1,,
Hedgehog _off_ state,Reactome,1,GLI2_HUMAN,43 (44),0.276,1,,
Formation of Incision Complex in GG-NER,Reactome,1,CHD1L_HUMAN,43 (43),0.276,1,,
IL-6 signaling pathway,Wikipathways,1,TYK2_HUMAN,43 (43),0.276,1,,
Homology Directed Repair,Reactome,2,CCNA2_HUMAN;XRCC1_HUMAN,140 (141),0.281,1,,
PLK1 signaling events,PID,1,CENPE_HUMAN,44 (44),0.281,1,,
Signaling by NOTCH3,Reactome,1,PLXD1_HUMAN,44 (44),0.281,1,,
TP53 Regulates Transcription of Cell Death Genes,Reactome,1,PIDD1_HUMAN,44 (44),0.281,1,,
ABC transporters - Homo sapiens (human),KEGG,1,ABCD2_HUMAN,44 (44),0.281,1,,
Heart Development,Wikipathways,1,NFAC3_HUMAN,44 (47),0.281,1,,
Interleukin-11 Signaling Pathway,Wikipathways,1,TYK2_HUMAN,44 (44),0.281,1,,
Structural Pathway of Interleukin 1 (IL-1),Wikipathways,1,M3K8_HUMAN,44 (44),0.281,1,,
Cell Cycle Checkpoints,Reactome,3,CCNA2_HUMAN;CENPE_HUMAN;CENPF_HUMAN,249 (250),0.285,1,,
Direct p53 effectors,PID,2,APC_HUMAN;PIDD1_HUMAN,142 (143),0.287,1,,
HATs acetylate histones,Reactome,2,HCFC1_HUMAN;JADE3_HUMAN,142 (142),0.287,1,,
NRF2 pathway,Wikipathways,2,PRDX1_HUMAN;THIO_HUMAN,142 (142),0.287,1,,
Basal transcription factors - Homo sapiens (human),KEGG,1,RBP56_HUMAN,45 (45),0.287,1,,
Switching of origins to a post-replicative state,Reactome,1,CCNA2_HUMAN,45 (46),0.287,1,,
Notch Signaling,Wikipathways,1,DLL3_HUMAN,45 (45),0.287,1,,
Glycolysis Gluconeogenesis,INOH,1,AGT2_HUMAN,45 (46),0.287,1,,
Cell Cycle_ Mitotic,Reactome,5,ALMS1_HUMAN;CCNA2_HUMAN;CENPE_HUMAN;SMC3_HUMAN;CENPF_HUMAN,479 (481),0.287,1,,
AndrogenReceptor,NetPath,2,CASP7_HUMAN;PRDX1_HUMAN,143 (143),0.289,1,,
TNF receptor signaling pathway ,PID,1,THIO_HUMAN,46 (46),0.292,1,,
Presenilin action in Notch and Wnt signaling,PID,1,APC_HUMAN,46 (46),0.292,1,,
RNA Polymerase II Promoter Escape,Reactome,1,RBP56_HUMAN,46 (46),0.292,1,,
Regulation of Microtubule Cytoskeleton,Wikipathways,1,APC_HUMAN,46 (46),0.292,1,,
Hepatitis B - Homo sapiens (human),KEGG,2,CCNA2_HUMAN;NFAC3_HUMAN,144 (144),0.292,1,,
Trans-sulfuration pathway,Wikipathways,1,DNMT1_HUMAN,47 (47),0.297,1,,
RNA Polymerase II HIV Promoter Escape,Reactome,1,RBP56_HUMAN,47 (47),0.297,1,,
RNA Polymerase II Transcription Initiation,Reactome,1,RBP56_HUMAN,47 (47),0.297,1,,
RNA Polymerase II Transcription Initiation And Promoter Clearance,Reactome,1,RBP56_HUMAN,47 (47),0.297,1,,
Nucleotide-binding domain_ leucine rich repeat containing receptor (NLR) signaling pathways,Reactome,1,THIO_HUMAN,47 (47),0.297,1,,
Energy Metabolism,Wikipathways,1,FOXO1_HUMAN,47 (47),0.297,1,,
Meiotic synapsis,Reactome,1,SMC3_HUMAN,47 (47),0.297,1,,
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,Reactome,1,RBP56_HUMAN,47 (47),0.297,1,,
HIV Transcription Initiation,Reactome,1,RBP56_HUMAN,47 (47),0.297,1,,
Breast cancer - Homo sapiens (human),KEGG,2,DLL3_HUMAN;APC_HUMAN,147 (147),0.301,1,,
Notch-mediated HES/HEY network,PID,1,TWST1_HUMAN,48 (48),0.303,1,,
Valine_ leucine and isoleucine degradation - Homo sapiens (human),KEGG,1,AGT2_HUMAN,48 (48),0.303,1,,
agrin in postsynaptic differentiation,BioCarta,1,LAMA5_HUMAN,48 (48),0.303,1,,
Notch signaling pathway - Homo sapiens (human),KEGG,1,DLL3_HUMAN,48 (48),0.303,1,,
Regulation of Actin Cytoskeleton,Wikipathways,2,APC_HUMAN;VILI_HUMAN,149 (151),0.306,1,,
N-Glycan biosynthesis - Homo sapiens (human),KEGG,1,OST48_HUMAN,49 (49),0.308,1,,
Calcineurin-regulated NFAT-dependent transcription in lymphocytes,PID,1,NFAC3_HUMAN,49 (49),0.308,1,,
FoxO family signaling,PID,1,FOXO1_HUMAN,49 (50),0.308,1,,
Retrograde transport at the Trans-Golgi-Network,Reactome,1,GOGA4_HUMAN,49 (49),0.308,1,,
Hepatitis C and Hepatocellular Carcinoma,Wikipathways,1,CASP7_HUMAN,49 (56),0.308,1,,
Angiopoietin receptor Tie2-mediated signaling,PID,1,FOXO1_HUMAN,50 (50),0.313,1,,
Vibrio cholerae infection - Homo sapiens (human),KEGG,1,VATH_HUMAN,50 (50),0.313,1,,
Mitochondrial biogenesis,Reactome,1,HCFC1_HUMAN,50 (53),0.313,1,,
Translation Factors,Wikipathways,1,EIF3A_HUMAN,50 (50),0.313,1,,
JAK STAT MolecularVariation 2,INOH,1,TYK2_HUMAN,50 (50),0.313,1,,
Photodynamic therapy-induced AP-1 survival signaling.,Wikipathways,1,CCNA2_HUMAN,50 (50),0.313,1,,
Vesicle-mediated transport,Reactome,6,CENPE_HUMAN;C2CD5_HUMAN;GOGA4_HUMAN;KIF3A_HUMAN;KIF1C_HUMAN;GALT2_HUMAN,620 (620),0.318,1,,
IL3,NetPath,1,FOXO1_HUMAN,51 (51),0.318,1,,
HDMs demethylate histones,Reactome,1,KDM5D_HUMAN,51 (51),0.318,1,,
Regulation of Androgen receptor activity,PID,1,FOXO1_HUMAN,51 (51),0.318,1,,
TP53 Regulates Transcription of Cell Cycle Genes,Reactome,1,CCNA2_HUMAN,51 (51),0.318,1,,
Aminosugars metabolism,EHMN,1,S38A3_HUMAN,51 (51),0.318,1,,
Wnt Signaling Pathway,Wikipathways,1,APC_HUMAN,51 (51),0.318,1,,
Breast cancer pathway,Wikipathways,2,DLL3_HUMAN;APC_HUMAN,154 (154),0.32,1,,
Amino acid and oligopeptide SLC transporters,Reactome,1,S38A3_HUMAN,52 (52),0.323,1,,
One carbon metabolism and related pathways,Wikipathways,1,AGT2_HUMAN,52 (52),0.323,1,,
Notch signaling pathway,PID,1,DLL3_HUMAN,53 (54),0.328,1,,
Posttranslational regulation of adherens junction stability and dissassembly,PID,1,SNX1_HUMAN,53 (53),0.328,1,,
hiv-1 nef: negative effector of fas and tnf,BioCarta,1,CASP7_HUMAN,53 (53),0.328,1,,
Apoptosis-related network due to altered Notch3 in ovarian cancer,Wikipathways,1,CASP7_HUMAN,53 (53),0.328,1,,
Interferon type I signaling pathways,Wikipathways,1,TYK2_HUMAN,54 (54),0.333,1,,
TCR signaling in na&#xef;ve CD8+ T cells,PID,1,M3K8_HUMAN,54 (56),0.333,1,,
IL-4 Signaling Pathway,Wikipathways,1,TYK2_HUMAN,54 (54),0.333,1,,
Epithelial to mesenchymal transition in colorectal cancer,Wikipathways,2,DLL3_HUMAN;TWST1_HUMAN,159 (160),0.334,1,,
Legionellosis - Homo sapiens (human),KEGG,1,CASP7_HUMAN,55 (55),0.338,1,,
Regulation of TP53 Activity,Reactome,2,CCNA2_HUMAN;RBP56_HUMAN,161 (162),0.339,1,,
EGF-EGFR Signaling Pathway,Wikipathways,2,TWST1_HUMAN;FOXO1_HUMAN,162 (162),0.342,1,,
Necroptosis - Homo sapiens (human),KEGG,2,TYK2_HUMAN;PYGL_HUMAN,162 (162),0.342,1,,
Deadenylation-dependent mRNA decay,Reactome,1,EDC3_HUMAN,56 (56),0.343,1,,
cGMP-PKG signaling pathway - Homo sapiens (human),KEGG,2,MYH7_HUMAN;NFAC3_HUMAN,163 (163),0.344,1,,
p53 pathway,PID,1,CCNA2_HUMAN,57 (58),0.348,1,,
mapkinase signaling pathway,BioCarta,1,M3K8_HUMAN,57 (57),0.348,1,,
Iron uptake and transport,Reactome,1,VATH_HUMAN,58 (58),0.353,1,,
Notch,NetPath,1,DLL3_HUMAN,58 (59),0.353,1,,
Viral myocarditis - Homo sapiens (human),KEGG,1,MYH7_HUMAN,58 (59),0.353,1,,
Endometrial cancer - Homo sapiens (human),KEGG,1,APC_HUMAN,58 (58),0.353,1,,
mRNA 3_-end processing,Reactome,1,RNPS1_HUMAN,58 (58),0.353,1,,
Hepatocellular carcinoma - Homo sapiens (human),KEGG,2,DPF1_HUMAN;APC_HUMAN,167 (168),0.355,1,,
DNA Double-Strand Break Repair,Reactome,2,CCNA2_HUMAN;XRCC1_HUMAN,168 (169),0.358,1,,
NOD-like receptor signaling pathway - Homo sapiens (human),KEGG,2,TYK2_HUMAN;THIO_HUMAN,168 (168),0.358,1,,
superpathway of purine nucleotide salvage,HumanCyc,1,VATH_HUMAN,59 (59),0.358,1,,
ABC-family proteins mediated transport,Reactome,1,ABCD2_HUMAN,59 (59),0.358,1,,
Lysine metabolism,EHMN,1,KMT2C_HUMAN,59 (60),0.358,1,,
Lysine degradation - Homo sapiens (human),KEGG,1,KMT2C_HUMAN,59 (59),0.358,1,,
Interleukin-1 signaling,Reactome,1,M3K8_HUMAN,60 (60),0.363,1,,
ATF-2 transcription factor network,PID,1,CCNA2_HUMAN,60 (60),0.363,1,,
Notch Signaling Pathway,Wikipathways,1,DLL3_HUMAN,61 (61),0.368,1,,
Coregulation of Androgen receptor activity,PID,1,PRDX1_HUMAN,61 (61),0.368,1,,
Signaling by MET,Reactome,1,LAMA5_HUMAN,61 (61),0.368,1,,
T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection,Wikipathways,1,M3K8_HUMAN,61 (63),0.368,1,,
TGF_beta_Receptor,NetPath,2,SNX1_HUMAN;FOXO1_HUMAN,173 (174),0.371,1,,
Purine metabolism - Homo sapiens (human),KEGG,2,PUR2_HUMAN;GUC2F_HUMAN,173 (174),0.371,1,,
Leptin,NetPath,1,FOXO1_HUMAN,62 (62),0.372,1,,
Longevity regulating pathway - multiple species - Homo sapiens (human),KEGG,1,FOXO1_HUMAN,62 (62),0.372,1,,
Endochondral Ossification,Wikipathways,1,KIF3A_HUMAN,63 (63),0.377,1,,
IL4,NetPath,1,TYK2_HUMAN,63 (63),0.377,1,,
IL12-mediated signaling events,PID,1,TYK2_HUMAN,63 (65),0.377,1,,
Synaptic vesicle cycle - Homo sapiens (human),KEGG,1,VATH_HUMAN,63 (63),0.377,1,,
Endometrial cancer,Wikipathways,1,APC_HUMAN,63 (63),0.377,1,,
Cell-cell junction organization,Reactome,1,INADL_HUMAN,63 (64),0.377,1,,
MECP2 and Associated Rett Syndrome,Wikipathways,1,SMC3_HUMAN,63 (63),0.377,1,,
Pathways Affected in Adenoid Cystic Carcinoma,Wikipathways,1,KMT2C_HUMAN,63 (63),0.377,1,,
Genotoxicity pathway,Wikipathways,1,CENPE_HUMAN,64 (64),0.382,1,,
Peroxisomal protein import,Reactome,1,ECH1_HUMAN,64 (64),0.382,1,,
Semaphorin interactions,Reactome,1,PLXD1_HUMAN,64 (64),0.382,1,,
Association Between Physico-Chemical Features and Toxicity Associated Pathways,Wikipathways,1,APC_HUMAN,64 (65),0.382,1,,
Interleukin-17 signaling,Reactome,1,M3K8_HUMAN,65 (65),0.386,1,,
IL4-mediated signaling events,PID,1,PAR14_HUMAN,65 (65),0.386,1,,
MAP kinase activation,Reactome,1,M3K8_HUMAN,65 (65),0.386,1,,
Folate Metabolism,Wikipathways,1,PUR2_HUMAN,65 (66),0.386,1,,
Translation,Reactome,3,OST48_HUMAN;RS2_HUMAN;EIF3A_HUMAN,299 (310),0.387,1,,
Beta1 integrin cell surface interactions,PID,1,LAMA5_HUMAN,66 (66),0.391,1,,
Histone Modifications,Wikipathways,1,KMT2C_HUMAN,66 (66),0.391,1,,
Focal Adhesion-PI3K-Akt-mTOR-signaling pathway,Wikipathways,3,LAMA5_HUMAN;FOXO1_HUMAN;TENR_HUMAN,302 (302),0.393,1,,
DNA methylation,Reactome,1,DNMT1_HUMAN,67 (67),0.396,1,,
Downstream signaling in na&#xef;ve CD8+ T cells,PID,1,NFAC3_HUMAN,67 (69),0.396,1,,
Cleavage of Growing Transcript in the Termination Region ,Reactome,1,RNPS1_HUMAN,67 (67),0.396,1,,
RNA Polymerase II Transcription Termination,Reactome,1,RNPS1_HUMAN,67 (67),0.396,1,,
O-linked glycosylation of mucins,Reactome,1,GALT2_HUMAN,67 (67),0.396,1,,
Gap-filling DNA repair synthesis and ligation in TC-NER,Reactome,1,XRCC1_HUMAN,67 (68),0.396,1,,
Non-genomic actions of 1_25 dihydroxyvitamin D3,Wikipathways,1,TYK2_HUMAN,68 (68),0.4,1,,
DNA Damage Response,Wikipathways,1,PIDD1_HUMAN,68 (68),0.4,1,,
Collagen biosynthesis and modifying enzymes,Reactome,1,ATS14_HUMAN,68 (68),0.4,1,,
Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human),KEGG,1,VATH_HUMAN,68 (68),0.4,1,,
Prolactin,NetPath,1,TYK2_HUMAN,68 (70),0.4,1,,
AMP-activated Protein Kinase (AMPK) Signaling,Wikipathways,1,CCNA2_HUMAN,68 (68),0.4,1,,
Endoderm Differentiation,Wikipathways,1,APC_HUMAN,68 (71),0.4,1,,
Wnt,NetPath,1,APC_HUMAN,68 (69),0.4,1,,
Transcriptional misregulation in cancer - Homo sapiens (human),KEGG,2,RBP56_HUMAN;FOXO1_HUMAN,185 (186),0.403,1,,
Herpes simplex infection - Homo sapiens (human),KEGG,2,TYK2_HUMAN;HCFC1_HUMAN,185 (185),0.403,1,,
IL-7 signaling,INOH,2,TYK2_HUMAN;M3K8_HUMAN,185 (185),0.403,1,,
TP53 Regulates Transcription of DNA Repair Genes,Reactome,1,CDK13_HUMAN,69 (70),0.405,1,,
Loss of Nlp from mitotic centrosomes,Reactome,1,ALMS1_HUMAN,69 (69),0.405,1,,
Loss of proteins required for interphase microtubule organization from the centrosome,Reactome,1,ALMS1_HUMAN,69 (69),0.405,1,,
EPO signaling,INOH,2,TYK2_HUMAN;M3K8_HUMAN,186 (186),0.406,1,,
Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human),KEGG,2,TYK2_HUMAN;NFAC3_HUMAN,186 (186),0.406,1,,
Cilium Assembly,Reactome,2,ALMS1_HUMAN;KIF3A_HUMAN,187 (187),0.409,1,,
RNA polymerase II transcribes snRNA genes,Reactome,1,ELL2_HUMAN,70 (77),0.409,1,,
AP-1 transcription factor network,PID,1,NFAC3_HUMAN,70 (70),0.409,1,,
Alpha6Beta4Integrin,NetPath,1,LAMA5_HUMAN,70 (71),0.409,1,,
B cell receptor signaling pathway - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,70 (71),0.409,1,,
Glucocorticoid Receptor Pathway,Wikipathways,1,NAV3_HUMAN,70 (71),0.409,1,,
Interferon alpha/beta signaling,Reactome,1,TYK2_HUMAN,70 (70),0.409,1,,
Cell Cycle,Reactome,5,ALMS1_HUMAN;CCNA2_HUMAN;CENPE_HUMAN;SMC3_HUMAN;CENPF_HUMAN,562 (564),0.411,1,,
Cellular Senescence,Reactome,2,CCNA2_HUMAN;THIO_HUMAN,188 (189),0.411,1,,
VEGF,INOH,2,TYK2_HUMAN;M3K8_HUMAN,188 (188),0.411,1,,
CDC42 signaling events,PID,1,APC_HUMAN,71 (71),0.414,1,,
TCF dependent signaling in response to WNT,Reactome,2,CHD8_HUMAN;APC_HUMAN,189 (190),0.414,1,,
PKMTs methylate histone lysines,Reactome,1,KMT2C_HUMAN,72 (73),0.418,1,,
p53 signaling pathway - Homo sapiens (human),KEGG,1,PIDD1_HUMAN,72 (72),0.418,1,,
AURKA Activation by TPX2,Reactome,1,ALMS1_HUMAN,72 (72),0.418,1,,
miRNA Regulation of DNA Damage Response,Wikipathways,1,PIDD1_HUMAN,72 (89),0.418,1,,
Transport of Mature mRNA derived from an Intron-Containing Transcript,Reactome,1,RNPS1_HUMAN,73 (73),0.422,1,,
Chromosomal and microsatellite instability in colorectal cancer,Wikipathways,1,APC_HUMAN,73 (73),0.422,1,,
RMTs methylate histone arginines,Reactome,1,RS2_HUMAN,74 (74),0.427,1,,
Synthesis of DNA,Reactome,1,CCNA2_HUMAN,74 (75),0.427,1,,
HIV Infection,Reactome,2,RBP56_HUMAN;VATH_HUMAN,195 (197),0.429,1,,
Costimulation by the CD28 family,Reactome,1,M3K8_HUMAN,75 (77),0.431,1,,
Signaling by Insulin receptor,Reactome,1,VATH_HUMAN,75 (75),0.431,1,,
Peptide GPCRs,Wikipathways,1,NMBR_HUMAN,75 (75),0.431,1,,
PRC2 methylates histones and DNA,Reactome,1,DNMT1_HUMAN,75 (75),0.431,1,,
Viral Acute Myocarditis,Wikipathways,1,CASP7_HUMAN,76 (76),0.435,1,,
Transcription of the HIV genome,Reactome,1,RBP56_HUMAN,76 (77),0.435,1,,
SUMOylation of DNA damage response and repair proteins,Reactome,1,SMC3_HUMAN,76 (76),0.435,1,,
Pertussis - Homo sapiens (human),KEGG,1,CASP7_HUMAN,76 (76),0.435,1,,
G1/S Transition,Reactome,1,CCNA2_HUMAN,76 (76),0.435,1,,
Leptin signaling pathway,Wikipathways,1,FOXO1_HUMAN,76 (76),0.435,1,,
IL2,NetPath,1,VILI_HUMAN,76 (76),0.435,1,,
Focal Adhesion,Wikipathways,2,LAMA5_HUMAN;TENR_HUMAN,198 (198),0.437,1,,
Focal adhesion - Homo sapiens (human),KEGG,2,TENR_HUMAN;LAMA5_HUMAN,199 (199),0.44,1,,
Regulation of nuclear SMAD2/3 signaling,PID,1,FOXO1_HUMAN,77 (78),0.44,1,,
Interleukin-1 family signaling,Reactome,1,M3K8_HUMAN,77 (77),0.44,1,,
insulin,INOH,1,FOXO1_HUMAN,78 (78),0.444,1,,
Cardiac muscle contraction - Homo sapiens (human),KEGG,1,MYH7_HUMAN,78 (78),0.444,1,,
Meiosis,Reactome,1,SMC3_HUMAN,78 (78),0.444,1,,
Glycine_ serine_ alanine and threonine metabolism,EHMN,1,S38A3_HUMAN,78 (78),0.444,1,,
Methionine and cysteine metabolism,EHMN,1,DNMT1_HUMAN,78 (78),0.444,1,,
Viral carcinogenesis - Homo sapiens (human),KEGG,2,CCNA2_HUMAN;PRS4_HUMAN,201 (201),0.445,1,,
Drug metabolism - other enzymes - Homo sapiens (human),KEGG,1,UPP2_HUMAN,79 (79),0.448,1,,
p73 transcription factor network,PID,1,CCNA2_HUMAN,79 (79),0.448,1,,
DNA Replication,Reactome,1,CCNA2_HUMAN,79 (80),0.448,1,,
Recruitment of NuMA to mitotic centrosomes,Reactome,1,ALMS1_HUMAN,79 (79),0.448,1,,
Alzheimers Disease,Wikipathways,1,CASP7_HUMAN,79 (145),0.448,1,,
Metabolism of amino acids and derivatives,Reactome,3,FOLH1_HUMAN;RS2_HUMAN;AGT2_HUMAN,330 (342),0.449,1,,
Recruitment of mitotic centrosome proteins and complexes,Reactome,1,ALMS1_HUMAN,80 (80),0.452,1,,
Centrosome maturation,Reactome,1,ALMS1_HUMAN,80 (80),0.452,1,,
Transcription-Coupled Nucleotide Excision Repair (TC-NER),Reactome,1,XRCC1_HUMAN,80 (81),0.452,1,,
Post-translational protein modification,Reactome,11,PRS4_HUMAN;SMC3_HUMAN;PRS6B_HUMAN;RS2_HUMAN;PSMD2_HUMAN;HCFC1_HUMAN;OST48_HUMAN;GALT2_HUMAN;APC_HUMAN;CCNA2_HUMAN;ATS14_HUMAN,1377 (1383),0.455,1,,
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met),PID,1,APC_HUMAN,81 (82),0.456,1,,
insulin Mam,INOH,1,FOXO1_HUMAN,82 (82),0.46,1,,
Signaling Pathways in Glioblastoma,Wikipathways,1,FOXO1_HUMAN,82 (83),0.46,1,,
Transport of Mature Transcript to Cytoplasm,Reactome,1,RNPS1_HUMAN,82 (82),0.46,1,,
Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human),KEGG,1,MYH7_HUMAN,83 (83),0.464,1,,
C-type lectin receptors (CLRs),Reactome,1,NFAC3_HUMAN,83 (83),0.464,1,,
Apoptosis,Wikipathways,1,CASP7_HUMAN,84 (87),0.468,1,,
CXCR4-mediated signaling events,PID,1,FOXO1_HUMAN,85 (87),0.472,1,,
Cellular responses to stress,Reactome,3,CCNA2_HUMAN;PRDX1_HUMAN;THIO_HUMAN,343 (345),0.474,1,,
Transport of bile salts and organic acids_ metal ions and amine compounds,Reactome,1,ZNT3_HUMAN,86 (87),0.476,1,,
Colorectal cancer - Homo sapiens (human),KEGG,1,APC_HUMAN,86 (86),0.476,1,,
MyD88 cascade initiated on plasma membrane,Reactome,1,M3K8_HUMAN,87 (87),0.48,1,,
Toll Like Receptor 10 (TLR10) Cascade,Reactome,1,M3K8_HUMAN,87 (87),0.48,1,,
RNA Polymerase II Pre-transcription Events,Reactome,1,RBP56_HUMAN,87 (88),0.48,1,,
Toll Like Receptor 5 (TLR5) Cascade,Reactome,1,M3K8_HUMAN,87 (87),0.48,1,,
Regulation of PLK1 Activity at G2/M Transition,Reactome,1,ALMS1_HUMAN,87 (87),0.48,1,,
Cytoplasmic Ribosomal Proteins,Wikipathways,1,RS2_HUMAN,88 (88),0.484,1,,
Host Interactions of HIV factors,Reactome,1,VATH_HUMAN,88 (89),0.484,1,,
GABAergic synapse - Homo sapiens (human),KEGG,1,S38A3_HUMAN,88 (88),0.484,1,,
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,Reactome,1,M3K8_HUMAN,88 (88),0.484,1,,
Cell junction organization,Reactome,1,INADL_HUMAN,88 (89),0.484,1,,
Dilated cardiomyopathy (DCM) - Homo sapiens (human),KEGG,1,MYH7_HUMAN,89 (90),0.488,1,,
Rheumatoid arthritis - Homo sapiens (human),KEGG,1,VATH_HUMAN,89 (90),0.488,1,,
Longevity regulating pathway - Homo sapiens (human),KEGG,1,FOXO1_HUMAN,89 (89),0.488,1,,
Human T-cell leukemia virus 1 infection - Homo sapiens (human),KEGG,2,CCNA2_HUMAN;NFAC3_HUMAN,219 (219),0.489,1,,
Toll Like Receptor 7/8 (TLR7/8) Cascade,Reactome,1,M3K8_HUMAN,90 (90),0.492,1,,
Protein digestion and absorption - Homo sapiens (human),KEGG,1,MEP1A_HUMAN,90 (90),0.492,1,,
MyD88 dependent cascade initiated on endosome,Reactome,1,M3K8_HUMAN,90 (90),0.492,1,,
ErbB Signaling Pathway,Wikipathways,1,FOXO1_HUMAN,91 (92),0.496,1,,
Allograft Rejection,Wikipathways,1,CASP7_HUMAN,91 (91),0.496,1,,
Purine metabolism,EHMN,2,GUC2F_HUMAN;PM34_HUMAN,223 (223),0.499,1,,
Collagen formation,Reactome,1,ATS14_HUMAN,92 (92),0.5,1,,
Peptide chain elongation,Reactome,1,RS2_HUMAN,92 (101),0.5,1,,
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function,Reactome,1,KMT2C_HUMAN,92 (94),0.5,1,,
Small cell lung cancer - Homo sapiens (human),KEGG,1,LAMA5_HUMAN,93 (93),0.503,1,,
Toll Like Receptor 9 (TLR9) Cascade,Reactome,1,M3K8_HUMAN,94 (94),0.507,1,,
NF-kappa B signaling pathway - Homo sapiens (human),KEGG,1,PIDD1_HUMAN,94 (95),0.507,1,,
PI3K/AKT Signaling in Cancer,Reactome,1,FOXO1_HUMAN,94 (94),0.507,1,,
Eukaryotic Translation Termination,Reactome,1,RS2_HUMAN,95 (104),0.511,1,,
Selenocysteine synthesis,Reactome,1,RS2_HUMAN,95 (104),0.511,1,,
Amoebiasis - Homo sapiens (human),KEGG,1,LAMA5_HUMAN,95 (96),0.511,1,,
Toll Like Receptor 3 (TLR3) Cascade,Reactome,1,M3K8_HUMAN,97 (97),0.518,1,,
Chaperonin-mediated protein folding,Reactome,1,BIG2_HUMAN,97 (97),0.518,1,,
Prostate cancer - Homo sapiens (human),KEGG,1,FOXO1_HUMAN,97 (97),0.518,1,,
Progesterone-mediated oocyte maturation - Homo sapiens (human),KEGG,1,CCNA2_HUMAN,97 (99),0.518,1,,
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC),Reactome,1,RS2_HUMAN,97 (106),0.518,1,,
Glycerophospholipid metabolism - Homo sapiens (human),KEGG,1,GPCP1_HUMAN,97 (97),0.518,1,,
Eukaryotic Translation Elongation,Reactome,1,RS2_HUMAN,97 (106),0.518,1,,
Anchoring of the basal body to the plasma membrane,Reactome,1,ALMS1_HUMAN,97 (97),0.518,1,,
MyD88:Mal cascade initiated on plasma membrane,Reactome,1,M3K8_HUMAN,97 (97),0.518,1,,
Toll Like Receptor TLR1:TLR2 Cascade,Reactome,1,M3K8_HUMAN,97 (97),0.518,1,,
Toll Like Receptor TLR6:TLR2 Cascade,Reactome,1,M3K8_HUMAN,97 (97),0.518,1,,
Toll Like Receptor 2 (TLR2) Cascade,Reactome,1,M3K8_HUMAN,97 (97),0.518,1,,
JAK STAT MolecularVariation 1,INOH,1,TYK2_HUMAN,98 (98),0.522,1,,
MAPK family signaling cascades,Reactome,2,TYK2_HUMAN;FOXO1_HUMAN,234 (237),0.524,1,,
Choline metabolism in cancer - Homo sapiens (human),KEGG,1,GPCP1_HUMAN,99 (99),0.525,1,,
AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human),KEGG,1,FOXO1_HUMAN,99 (99),0.525,1,,
Processing of DNA double-strand break ends,Reactome,1,CCNA2_HUMAN,99 (99),0.525,1,,
VEGFA-VEGFR2 Signaling Pathway,Wikipathways,2,FOXO1_HUMAN;THIO_HUMAN,236 (236),0.529,1,,
Metabolism of proteins,Reactome,15,ECH1_HUMAN;APC_HUMAN;GALT2_HUMAN;SMC3_HUMAN;BIG2_HUMAN;RS2_HUMAN;PSMD2_HUMAN;HCFC1_HUMAN;PRS6B_HUMAN;OST48_HUMAN;EIF3A_HUMAN;PRS4_HUMAN;CCNA2_HUMAN;ATS14_HUMAN;THIO_HUMAN,1991 (2008),0.529,1,,
Disease,Reactome,4,FOXO1_HUMAN;PRDX1_HUMAN;RBP56_HUMAN;VATH_HUMAN,508 (510),0.529,1,,
Pyrimidine metabolism - Homo sapiens (human),KEGG,1,UPP2_HUMAN,101 (101),0.532,1,,
TRIF(TICAM1)-mediated TLR4 signaling ,Reactome,1,M3K8_HUMAN,101 (101),0.532,1,,
MyD88-independent TLR4 cascade ,Reactome,1,M3K8_HUMAN,101 (101),0.532,1,,
Wnt Signaling Pathway and Pluripotency,Wikipathways,1,APC_HUMAN,101 (101),0.532,1,,
Toll-like Receptor Signaling Pathway,Wikipathways,1,M3K8_HUMAN,102 (102),0.536,1,,
Visual phototransduction,Reactome,1,GUC2F_HUMAN,102 (102),0.536,1,,
FCERI mediated Ca+2 mobilization,Reactome,1,NFAC3_HUMAN,103 (108),0.539,1,,
Protein folding,Reactome,1,BIG2_HUMAN,103 (103),0.539,1,,
TCR,NetPath,2,DBNL_HUMAN;HOME3_HUMAN,241 (245),0.54,1,,
Reproduction,Reactome,1,SMC3_HUMAN,104 (104),0.543,1,,
Toll-like receptor signaling pathway - Homo sapiens (human),KEGG,1,M3K8_HUMAN,104 (104),0.543,1,,
Mitotic G1-G1/S phases,Reactome,1,CCNA2_HUMAN,104 (104),0.543,1,,
C-type lectin receptor signaling pathway - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,104 (104),0.543,1,,
JAK-STAT-Core,Signalink,1,TYK2_HUMAN,104 (104),0.543,1,,
Urea cycle and metabolism of arginine_ proline_ glutamate_ aspartate and asparagine,EHMN,1,S38A3_HUMAN,104 (106),0.543,1,,
EGF-Core,Signalink,1,M3K8_HUMAN,105 (105),0.546,1,,
MAPK Signaling Pathway,Wikipathways,2,M3K8_HUMAN;NFAC3_HUMAN,246 (246),0.552,1,,
Hemostasis,Reactome,5,VTI1B_HUMAN;CENPE_HUMAN;KIF1C_HUMAN;GSLG1_HUMAN;KIF3A_HUMAN,662 (668),0.555,1,,
Thermogenesis,Wikipathways,1,DPF1_HUMAN,108 (108),0.557,1,,
NoRC negatively regulates rRNA expression,Reactome,1,DNMT1_HUMAN,108 (108),0.557,1,,
Infectious disease,Reactome,2,RBP56_HUMAN;VATH_HUMAN,251 (253),0.563,1,,
DNA Damage Response (only ATM dependent),Wikipathways,1,APC_HUMAN,110 (110),0.563,1,,
Negative epigenetic regulation of rRNA expression,Reactome,1,DNMT1_HUMAN,111 (111),0.567,1,,
Senescence-Associated Secretory Phenotype (SASP),Reactome,1,CCNA2_HUMAN,111 (112),0.567,1,,
Signaling by Interleukins,Reactome,2,TYK2_HUMAN;M3K8_HUMAN,254 (254),0.569,1,,
Spinal Cord Injury,Wikipathways,1,ROS1_HUMAN,115 (117),0.579,1,,
Thyroid hormone signaling pathway - Homo sapiens (human),KEGG,1,FOXO1_HUMAN,116 (116),0.583,1,,
ESC Pluripotency Pathways,Wikipathways,1,APC_HUMAN,116 (116),0.583,1,,
Signaling by NOTCH,Reactome,1,PLXD1_HUMAN,117 (120),0.586,1,,
miR-targeted genes in lymphocytes - TarBase,Wikipathways,3,PLXD1_HUMAN;VTI1B_HUMAN;M3K8_HUMAN,409 (489),0.594,1,,
SUMO E3 ligases SUMOylate target proteins,Reactome,1,SMC3_HUMAN,120 (120),0.595,1,,
miR-targeted genes in epithelium - TarBase,Wikipathways,2,VTI1B_HUMAN;M3K8_HUMAN,267 (333),0.596,1,,
Selenoamino acid metabolism,Reactome,1,RS2_HUMAN,121 (130),0.598,1,,
Cellular responses to external stimuli,Reactome,3,CCNA2_HUMAN;PRDX1_HUMAN;THIO_HUMAN,412 (414),0.599,1,,
miR-targeted genes in squamous cell - TarBase,Wikipathways,1,M3K8_HUMAN,122 (158),0.601,1,,
Oocyte meiosis - Homo sapiens (human),KEGG,1,SMC3_HUMAN,123 (125),0.604,1,,
Lysosome - Homo sapiens (human),KEGG,1,VATH_HUMAN,123 (123),0.604,1,,
Cell-Cell communication,Reactome,1,INADL_HUMAN,123 (124),0.604,1,,
Signaling by the B Cell Receptor (BCR),Reactome,1,NFAC3_HUMAN,124 (127),0.607,1,,
Integrin,INOH,1,SMC3_HUMAN,124 (124),0.607,1,,
Oxidative Stress Induced Senescence,Reactome,1,THIO_HUMAN,126 (126),0.613,1,,
SUMOylation,Reactome,1,SMC3_HUMAN,126 (126),0.613,1,,
Toll Like Receptor 4 (TLR4) Cascade,Reactome,1,M3K8_HUMAN,127 (127),0.616,1,,
Signaling by WNT,Reactome,2,CHD8_HUMAN;APC_HUMAN,277 (278),0.616,1,,
Immune System,Reactome,13,TYK2_HUMAN;NFAC3_HUMAN;PYGL_HUMAN;PSMD2_HUMAN;CDK13_HUMAN;M3K8_HUMAN;GRN_HUMAN;OST48_HUMAN;VATH_HUMAN;FRPD3_HUMAN;DBNL_HUMAN;MMP8_HUMAN;THIO_HUMAN,1825 (1840),0.618,1,,
Osteoclast differentiation - Homo sapiens (human),KEGG,1,TYK2_HUMAN,128 (128),0.619,1,,
Platelet degranulation ,Reactome,1,VTI1B_HUMAN,128 (129),0.619,1,,
Dopaminergic synapse - Homo sapiens (human),KEGG,1,KIF5C_HUMAN,131 (131),0.627,1,,
Measles - Homo sapiens (human),KEGG,1,TYK2_HUMAN,131 (132),0.627,1,,
Signaling by Rho GTPases,Reactome,3,RHG28_HUMAN;CENPE_HUMAN;CENPF_HUMAN,431 (435),0.629,1,,
Glycerophospholipid biosynthesis,Reactome,1,GPCP1_HUMAN,132 (133),0.63,1,,
Oxidative phosphorylation - Homo sapiens (human),KEGG,1,VATH_HUMAN,133 (133),0.633,1,,
Spliceosome - Homo sapiens (human),KEGG,1,PR40B_HUMAN,133 (134),0.633,1,,
Response to elevated platelet cytosolic Ca2+,Reactome,1,VTI1B_HUMAN,133 (134),0.633,1,,
Asparagine N-linked glycosylation,Reactome,2,OST48_HUMAN;PRS4_HUMAN,286 (286),0.634,1,,
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA),Reactome,1,CCNA2_HUMAN,134 (135),0.636,1,,
Ribosome - Homo sapiens (human),KEGG,1,RS2_HUMAN,135 (153),0.639,1,,
Pyrimidine metabolism,EHMN,1,UPP2_HUMAN,136 (136),0.641,1,,
Ubiquitin mediated proteolysis - Homo sapiens (human),KEGG,1,BIRC6_HUMAN,137 (137),0.644,1,,
Fluid shear stress and atherosclerosis - Homo sapiens (human),KEGG,1,THIO_HUMAN,138 (139),0.647,1,,
Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human),KEGG,1,APC_HUMAN,139 (139),0.649,1,,
Regulation of toll-like receptor signaling pathway,Wikipathways,1,M3K8_HUMAN,139 (143),0.649,1,,
MAPK signaling pathway - Homo sapiens (human),KEGG,2,M3K8_HUMAN;NFAC3_HUMAN,295 (295),0.651,1,,
Rho GTPase cycle,Reactome,1,RHG28_HUMAN,140 (144),0.652,1,,
Estrogen-dependent gene expression,Reactome,1,SMC3_HUMAN,141 (142),0.655,1,,
Late Phase of HIV Life Cycle,Reactome,1,RBP56_HUMAN,141 (143),0.655,1,,
RHO GTPase Effectors,Reactome,2,CENPE_HUMAN;CENPF_HUMAN,301 (301),0.662,1,,
Cell adhesion molecules (CAMs) - Homo sapiens (human),KEGG,1,GSLG1_HUMAN,144 (144),0.662,1,,
Adrenergic signaling in cardiomyocytes - Homo sapiens (human),KEGG,1,MYH7_HUMAN,144 (144),0.662,1,,
Brain-Derived Neurotrophic Factor (BDNF) signaling pathway,Wikipathways,1,APC_HUMAN,144 (144),0.662,1,,
Fc epsilon receptor (FCERI) signaling,Reactome,1,NFAC3_HUMAN,145 (150),0.665,1,,
EGFR1,NetPath,3,TYK2_HUMAN;RS2_HUMAN;FOXO1_HUMAN,455 (457),0.666,1,,
Gastric cancer - Homo sapiens (human),KEGG,1,APC_HUMAN,148 (149),0.672,1,,
Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human),KEGG,1,CASP7_HUMAN,149 (149),0.675,1,,
ESR-mediated signaling,Reactome,1,SMC3_HUMAN,149 (150),0.675,1,,
Epigenetic regulation of gene expression,Reactome,1,DNMT1_HUMAN,151 (151),0.68,1,,
Phagosome - Homo sapiens (human),KEGG,1,VATH_HUMAN,151 (152),0.68,1,,
mTOR signaling pathway - Homo sapiens (human),KEGG,1,VATH_HUMAN,151 (151),0.68,1,,
Oxytocin signaling pathway - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,152 (152),0.682,1,,
Nonalcoholic fatty liver disease,Wikipathways,1,CASP7_HUMAN,154 (155),0.687,1,,
HIV Life Cycle,Reactome,1,RBP56_HUMAN,154 (156),0.687,1,,
Toll-Like Receptors Cascades,Reactome,1,M3K8_HUMAN,154 (154),0.687,1,,
Cushing syndrome - Homo sapiens (human),KEGG,1,APC_HUMAN,154 (154),0.687,1,,
Hepatitis C - Homo sapiens (human),KEGG,1,TYK2_HUMAN,155 (155),0.689,1,,
Interferon Signaling,Reactome,1,TYK2_HUMAN,158 (158),0.696,1,,
JAK-STAT signaling pathway - Homo sapiens (human),KEGG,1,TYK2_HUMAN,162 (162),0.705,1,,
Protein processing in endoplasmic reticulum - Homo sapiens (human),KEGG,1,OST48_HUMAN,165 (165),0.712,1,,
Tight junction - Homo sapiens (human),KEGG,1,INADL_HUMAN,170 (170),0.723,1,,
PI3K-Akt Signaling Pathway,Wikipathways,2,LAMA5_HUMAN;TENR_HUMAN,339 (340),0.725,1,,
Alzheimer disease - Homo sapiens (human),KEGG,1,CASP7_HUMAN,171 (171),0.725,1,,
Influenza A - Homo sapiens (human),KEGG,1,TYK2_HUMAN,171 (171),0.725,1,,
Axon guidance - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,175 (175),0.733,1,,
Tuberculosis - Homo sapiens (human),KEGG,1,VATH_HUMAN,178 (179),0.739,1,,
Ion channel transport,Reactome,1,VATH_HUMAN,179 (179),0.741,1,,
PI3K-Akt signaling pathway - Homo sapiens (human),KEGG,2,LAMA5_HUMAN;TENR_HUMAN,353 (354),0.745,1,,
Vitamin D Receptor Pathway,Wikipathways,1,FOXO1_HUMAN,182 (184),0.747,1,,
Fatty acid metabolism,Reactome,1,PM34_HUMAN,187 (189),0.756,1,,
Neuronal System,Reactome,2,DBNL_HUMAN;HOME3_HUMAN,368 (368),0.766,1,,
Peptide ligand-binding receptors,Reactome,1,NMBR_HUMAN,194 (194),0.769,1,,
Signaling by Nuclear Receptors,Reactome,1,SMC3_HUMAN,194 (195),0.769,1,,
Muscle contraction,Reactome,1,MYH7_HUMAN,195 (195),0.771,1,,
Transcriptional regulation by RUNX1,Reactome,1,KMT2C_HUMAN,196 (198),0.773,1,,
Proteoglycans in cancer - Homo sapiens (human),KEGG,1,TWST1_HUMAN,198 (201),0.776,1,,
MAPK1/MAPK3 signaling,Reactome,1,TYK2_HUMAN,202 (203),0.783,1,,
Human immunodeficiency virus 1 infection - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,212 (212),0.799,1,,
G alpha (q) signalling events,Reactome,1,NMBR_HUMAN,213 (213),0.8,1,,
Regulation of actin cytoskeleton - Homo sapiens (human),KEGG,1,APC_HUMAN,213 (213),0.8,1,,
Cell surface interactions at the vascular wall,Reactome,1,GSLG1_HUMAN,213 (219),0.8,1,,
PIP3 activates AKT signaling,Reactome,1,FOXO1_HUMAN,214 (214),0.802,1,,
Phospholipid metabolism,Reactome,1,GPCP1_HUMAN,215 (216),0.803,1,,
Human cytomegalovirus infection - Homo sapiens (human),KEGG,1,NFAC3_HUMAN,225 (225),0.818,1,,
Thermogenesis - Homo sapiens (human),KEGG,1,DPF1_HUMAN,229 (229),0.823,1,,
Signaling by Receptor Tyrosine Kinases,Reactome,2,VATH_HUMAN;LAMA5_HUMAN,423 (423),0.829,1,,
Intracellular signaling by second messengers,Reactome,1,FOXO1_HUMAN,245 (245),0.844,1,,
Diseases of signal transduction,Reactome,1,FOXO1_HUMAN,248 (248),0.847,1,,
Platelet activation_ signaling and aggregation,Reactome,1,VTI1B_HUMAN,259 (260),0.859,1,,
GPCRs_ Class A Rhodopsin-like,Wikipathways,1,NMBR_HUMAN,260 (261),0.861,1,,
Cytokine Signaling in Immune system,Reactome,2,TYK2_HUMAN;M3K8_HUMAN,458 (458),0.861,1,,
GPCR signaling-G alpha i,INOH,1,DLL3_HUMAN,262 (262),0.863,1,,
GPCR signaling-pertussis toxin,INOH,1,DLL3_HUMAN,262 (262),0.863,1,,
Metabolism of carbohydrates,Reactome,1,PYGL_HUMAN,263 (264),0.864,1,,
GPCR signaling-cholera toxin,INOH,1,DLL3_HUMAN,270 (270),0.871,1,,
GPCR signaling-G alpha s Epac and ERK,INOH,1,DLL3_HUMAN,272 (272),0.873,1,,
GPCR signaling-G alpha q,INOH,1,DLL3_HUMAN,274 (274),0.875,1,,
Neuroactive ligand-receptor interaction - Homo sapiens (human),KEGG,1,NMBR_HUMAN,277 (277),0.878,1,,
GPCR signaling-G alpha s PKA and ERK,INOH,1,DLL3_HUMAN,285 (285),0.885,1,,
Signal Transduction,Reactome,15,CHD8_HUMAN;APC_HUMAN;SMC3_HUMAN;CENPE_HUMAN;LAMA5_HUMAN;TYK2_HUMAN;GUC2F_HUMAN;CENPF_HUMAN;RHG28_HUMAN;GLI2_HUMAN;PLXD1_HUMAN;VATH_HUMAN;KIF3A_HUMAN;FOXO1_HUMAN;NMBR_HUMAN,2634 (2647),0.91,1,,
Class A/1 (Rhodopsin-like receptors),Reactome,1,NMBR_HUMAN,330 (330),0.918,1,,
Axon guidance,Reactome,1,PLXD1_HUMAN,356 (358),0.933,1,,
Developmental Biology,Reactome,2,PLXD1_HUMAN;FOXO1_HUMAN,618 (620),0.949,1,,
G alpha (i) signalling events,Reactome,1,GUC2F_HUMAN,399 (400),0.952,1,,
Metabolism of lipids,Reactome,2,GPCP1_HUMAN;PM34_HUMAN,660 (664),0.961,1,,
Metabolism,Reactome,9,UPP2_HUMAN;GPCP1_HUMAN;AGT2_HUMAN;FOLH1_HUMAN;RS2_HUMAN;PYGL_HUMAN;PM34_HUMAN;PUR2_HUMAN;THIO_HUMAN,1954 (1972),0.966,1,,
Olfactory transduction - Homo sapiens (human),KEGG,1,NCKX4_HUMAN,446 (447),0.967,1,,
GPCR ligand binding,Reactome,1,NMBR_HUMAN,465 (466),0.971,1,,
Adaptive Immune System,Reactome,2,M3K8_HUMAN;NFAC3_HUMAN,722 (732),0.974,1,,
GPCR downstream signalling,Reactome,2,GUC2F_HUMAN;NMBR_HUMAN,1172 (1176),0.999,1,,
Signaling by GPCR,Reactome,2,GUC2F_HUMAN;NMBR_HUMAN,1235 (1240),0.999,1,,