This PDF file includes:

• Section S1. Description of bicarbonate uptake of Microcystis PCC 7941
• Section S2. Description of the mathematical model
• Section S3. Extrapolation of the model to lakes
• Fig. S1. Carbon uptake kinetics of Microcystis PCC 7941 acclimated to either low or high pCO₂.
• Fig. S2. Population density, inorganic carbon chemistry, and pH in chemostat experiments with Microcystis PCC 7941 at low and at high pCO₂.
• Table S1. Steady-state characteristics of the chemostat experiments with Microcystis PCC 7806 and Microcystis PCC 7941.
• Table S2. Kinetic parameters estimated from the carbon uptake experiments with Microcystis PCC 7806 and Microcystis PCC 7941.
• Table S3. Tests of significant differences between kinetic parameters estimated at low versus high pCO₂.
• Table S4. System parameters applied in the chemostat experiments.
• Table S5. Species parameters measured experimentally.
• Table S6. System parameters applied in the lake model.
• References (52–59)

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