Analysis Type: PANTHER Overrepresentation Test (Released 20190711) Annotation Version and Release Date: GO Ontology database Released 2019-07-03 Analyzed List: 100_id.txt (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20996) 100_id.txt (30) 100_id.txt (expected) 100_id.txt (over/under) 100_id.txt (fold Enrichment) 100_id.txt (raw P-value) 100_id.txt (FDR) chromatin silencing at rDNA (GO:0000183) 12 4 .02 + > 100 6.05E-09 3.85E-06 innate immune response in mucosa (GO:0002227) 20 5 .03 + > 100 2.17E-10 1.72E-07 nucleosome assembly (GO:0006334) 116 26 .17 + > 100 8.78E-54 1.40E-49 DNA replication-dependent nucleosome assembly (GO:0006335) 10 2 .01 + > 100 1.29E-04 3.41E-02 DNA replication-dependent nucleosome organization (GO:0034723) 10 2 .01 + > 100 1.29E-04 3.36E-02 chromatin assembly (GO:0031497) 133 26 .19 + > 100 2.18E-52 1.74E-48 nucleosome positioning (GO:0016584) 17 3 .02 + > 100 2.94E-06 1.20E-03 chromatin assembly or disassembly (GO:0006333) 154 26 .22 + > 100 7.14E-51 3.79E-47 depurination (GO:0045007) 12 2 .02 + > 100 1.77E-04 4.34E-02 mucosal immune response (GO:0002385) 30 5 .04 + > 100 1.31E-09 9.49E-07 nucleosome organization (GO:0034728) 157 26 .22 + > 100 1.13E-50 4.51E-47 organ or tissue specific immune response (GO:0002251) 33 5 .05 + > 100 2.02E-09 1.40E-06 negative regulation of chromatin silencing (GO:0031936) 20 3 .03 + > 100 4.55E-06 1.77E-03 DNA packaging (GO:0006323) 177 26 .25 + > 100 2.03E-49 6.45E-46 protein-DNA complex assembly (GO:0065004) 200 26 .29 + 90.98 3.93E-48 1.04E-44 antibacterial humoral response (GO:0019731) 39 5 .06 + 89.73 4.35E-09 2.88E-06 protein-DNA complex subunit organization (GO:0071824) 242 26 .35 + 75.19 4.18E-46 9.49E-43 regulation of megakaryocyte differentiation (GO:0045652) 54 5 .08 + 64.80 1.98E-08 1.21E-05 DNA conformation change (GO:0071103) 294 26 .42 + 61.89 5.13E-44 1.02E-40 protein heterotetramerization (GO:0051290) 34 3 .05 + 61.75 1.97E-05 6.67E-03 negative regulation of gene silencing (GO:0060969) 36 3 .05 + 58.32 2.31E-05 7.67E-03 regulation of chromatin silencing (GO:0031935) 38 3 .05 + 55.25 2.69E-05 8.74E-03 positive regulation of gene expression, epigenetic (GO:0045815) 64 5 .09 + 54.68 4.39E-08 2.49E-05 antimicrobial humoral immune response mediated by antimicrobial peptide (GO:0061844) 66 5 .09 + 53.02 5.08E-08 2.78E-05 chromosome condensation (GO:0030261) 43 3 .06 + 48.83 3.82E-05 1.21E-02 chromatin silencing (GO:0006342) 60 4 .09 + 46.66 2.02E-06 8.91E-04 chromatin organization involved in negative regulation of transcription (GO:0097549) 60 4 .09 + 46.66 2.02E-06 8.66E-04 negative regulation of DNA recombination (GO:0045910) 45 3 .06 + 46.66 4.34E-05 1.35E-02 negative regulation of chromatin organization (GO:1905268) 63 4 .09 + 44.44 2.42E-06 1.01E-03 negative regulation of gene expression, epigenetic (GO:0045814) 81 5 .12 + 43.20 1.34E-07 6.65E-05 chromatin organization involved in regulation of transcription (GO:0034401) 70 4 .10 + 39.99 3.61E-06 1.44E-03 regulation of gene silencing (GO:0060968) 127 7 .18 + 38.58 6.57E-10 4.98E-07 double-strand break repair via nonhomologous end joining (GO:0006303) 56 3 .08 + 37.49 8.07E-05 2.33E-02 defense response to Gram-positive bacterium (GO:0050830) 94 5 .13 + 37.23 2.71E-07 1.31E-04 non-recombinational repair (GO:0000726) 62 3 .09 + 33.86 1.08E-04 3.01E-02 regulation of gene silencing by miRNA (GO:0060964) 86 4 .12 + 32.55 7.90E-06 2.99E-03 regulation of posttranscriptional gene silencing (GO:0060147) 89 4 .13 + 31.45 9.00E-06 3.33E-03 regulation of gene silencing by RNA (GO:0060966) 89 4 .13 + 31.45 9.00E-06 3.25E-03 antimicrobial humoral response (GO:0019730) 113 5 .16 + 30.97 6.51E-07 3.05E-04 chromatin organization (GO:0006325) 695 29 .99 + 29.20 6.27E-42 1.11E-38 telomere organization (GO:0032200) 101 4 .14 + 27.72 1.46E-05 5.15E-03 regulation of gene expression, epigenetic (GO:0040029) 234 9 .33 + 26.92 3.67E-11 3.08E-08 negative regulation of chromosome organization (GO:2001251) 139 5 .20 + 25.18 1.74E-06 7.93E-04 cellular protein-containing complex assembly (GO:0034622) 838 26 1.20 + 21.71 1.48E-32 2.13E-29 chromosome organization (GO:0051276) 1056 29 1.51 + 19.22 9.28E-37 1.48E-33 gene silencing (GO:0016458) 152 4 .22 + 18.42 6.87E-05 2.03E-02 regulation of myeloid cell differentiation (GO:0045637) 228 5 .33 + 15.35 1.82E-05 6.29E-03 regulation of chromatin organization (GO:1902275) 191 4 .27 + 14.66 1.63E-04 4.05E-02 protein-containing complex assembly (GO:0065003) 1566 27 2.24 + 12.07 1.47E-27 1.95E-24 defense response to bacterium (GO:0042742) 327 5 .47 + 10.70 9.81E-05 2.79E-02 protein-containing complex subunit organization (GO:0043933) 1851 27 2.64 + 10.21 1.24E-25 1.52E-22 protein ubiquitination (GO:0016567) 687 10 .98 + 10.19 2.48E-08 1.46E-05 humoral immune response (GO:0006959) 344 5 .49 + 10.17 1.24E-04 3.40E-02 regulation of chromosome organization (GO:0033044) 351 5 .50 + 9.97 1.36E-04 3.49E-02 negative regulation of organelle organization (GO:0010639) 382 5 .55 + 9.16 2.01E-04 4.84E-02 protein modification by small protein conjugation (GO:0032446) 782 10 1.12 + 8.95 8.23E-08 4.22E-05 protein modification by small protein conjugation or removal (GO:0070647) 992 11 1.42 + 7.76 6.52E-08 3.46E-05 cellular component assembly (GO:0022607) 2528 27 3.61 + 7.47 4.79E-22 5.08E-19 negative regulation of cellular component organization (GO:0051129) 705 7 1.01 + 6.95 5.11E-05 1.56E-02 cellular component biogenesis (GO:0044085) 2758 27 3.94 + 6.85 4.79E-21 4.76E-18 organelle organization (GO:0006996) 3410 29 4.87 + 5.95 3.60E-22 4.09E-19 negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 1433 9 2.05 + 4.40 1.25E-04 3.38E-02 cellular component organization (GO:0016043) 5658 29 8.08 + 3.59 7.16E-16 6.70E-13 cellular component organization or biogenesis (GO:0071840) 5850 29 8.36 + 3.47 1.86E-15 1.64E-12 cellular protein metabolic process (GO:0044267) 3730 15 5.33 + 2.81 5.79E-05 1.74E-02 cellular macromolecule metabolic process (GO:0044260) 5088 17 7.27 + 2.34 1.45E-04 3.67E-02