Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via ubiquitinating SREBP chaperone SCAP — RNF5 induces cholesterol biosynthesis by ubiquitinating SCAP — Ring finger protein 5 activates sterol regulatory element–binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP — RNF5 induces cholesterol biosynthesis by ubiquitinating SCAP